diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1.json
index d8c0b52e44e..40991961779 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1.json
@@ -1 +1 @@
-{"AFINITOR": 499.4579594245425}
\ No newline at end of file
+{"BUPRENORPHINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10.json
index 302f0c26a54..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.685337015620538, "ACLIDINIUM": 1.9639961023471737, "ADALIMUMAB": 3.04602412329072, "ADCIRCA": 3.6878005562341896, "ADEMPAS": 4.511819407257338, "ADENURIC": 1.221297759781698, "AFINITOR": 1.5448171867706, "AIMOVIG": 3.292372458892356, "ALL": 2.357130840705633, "AMBRISENTAN": 1.4052485897836675, "ANTIBIOTICS": 2.102098540673646, "APREMILAST": 3.0218247559599405, "APREPITANT": 1.9837146168346984, "ARANESP": 18.733780709178777, "AZATHIOPRINE": 1.101613009995066, "AZILECT": 1.6147084852640148, "BARACLUDE": 1.2042064533510008, "BETMIGA": 1.727295769170437, "BIKTARVY": 1.877315517480224, "BISMUTH": 855.8100398003756, "BOSENTAN": 2.7564731483093547, "BRINTELLIX": 1.0961948479771535, "BYDUREON": 1.9188214066743488, "BYETTA": 1.7803940742468998, "CAPECITABINE": 1.1211039027934229, "CARBIDOPA": 4.538216519995293, "CEFUROXIME": 4.352179191775153, "CELECOXIB": 1.4210348447853016, "CELSENTRI": 2.213128316038894, "CETROTIDE": 18.80638548583657, "CHAMPIX": 2.825945050029496, "CHORIOGONADOTROPIN": 42.00036500958727, "CINRYZE": 1.3763235145558637, "CLOPIDOGREL": 2.158310917430628, "COMBIVIR": 2.1397018103290275, "CRIXIVAN": 3.458816071396651, "DAPAGLIFLOZIN": 4.480299620257311, "DARBEPOETIN": 19.936035137679664, "DARUNAVIR": 1.0222517275205674, "DULAGLUTIDE": 2.7440667201091835, "DULOXETINE": 1.0529803976555414, "ELLAONE": 6.230438585629753, "EMTRIVA": 2.7034248483745524, "ENOXAPARIN": 1.6503002669727185, "ENTRESTO": 1.34005041881419, "ENTYVIO": 2.6594084829990634, "EPCLUSA": 1.1398650796537009, "EPIVIR": 1.3761320389603031, "ESBRIET": 1.5237297544541455, "ESMYA": 2.532660524676507, "EUCREAS": 1.8568890697032885, "EXJADE": 2.024984914461906, "FASLODEX": 1.053859804493678, "FLUTICASONE": 15.486935086367971, "FOLLITROPIN": 36.76873033829075, "FORSTEO": 3.0141542916084347, "GALVUS": 2.431940454828467, "GENVOYA": 1.6861952222140455, "GLIVEC": 1.393935452548264, "GONALF": 27.44436965826181, "HARVONI": 1.3369599575995703, "HIZENTRA": 1.8901012231202787, "HYQVIA": 5.002028226268736, "IBUPROFEN": 1.0093356329647656, "IMATINIB": 1.4663251913140047, "INSULIN": 1.7714639254889204, "JAKAVI": 1.51797189164106, "JANUMET": 1.5123646425960566, "JANUVIA": 1.1642483854722945, "KAFTRIO": 2.9832252135417776, "KALETRA": 1.7460079612393749, "KETOCONAZOLE": 3.0062006333038283, "LONSURF": 2.029979046351197, "LUTROPIN": 72.30939874493079, "LUVERIS": 63.366491315461104, "MACITENTAN": 2.328803829800042, "MELATONIN": 1.740970931181735, "METFORMIN": 2.2104922963478755, "MOVYMIA": 2.8812252249388832, "MULTAQ": 1.1131207187764798, "NAGLAZYME": 1.1263296874569966, "NEXAVAR": 1.2136738830796154, "NORVIR": 1.6149612953740868, "OCALIVA": 4.050580729989552, "OCTREOTIDE": 3.718576062726355, "OFEV": 2.052415346549608, "OMALIZUMAB": 1.672613942251384, "OPSUMIT": 2.411093440593049, "ORGALUTRAN": 10.029114237798856, "OVITRELLE": 7.14126767522207, "OXYBUTYNIN": 2.377770569090449, "OZEMPIC": 2.5039593129162188, "PANTOPRAZOLE": 2.0025006641349647, "PEGASYS": 1.2565272180654747, "PEGINTRON": 1.136322389616669, "PUREGON": 19.11235954591917, "RANEXA": 1.4035902431641456, "REVESTIVE": 11.63332394511703, "RINVOQ": 1.0643359349074075, "RISPERIDONE": 1.0275569859099007, "ROTATEQ": 3.046152572389491, "RUBRACA": 1.750767517185991, "RUCONEST": 1.6492323207940858, "RYBELSUS": 6.12684179855822, "SAXENDA": 5.957598101981265, "SEMAGLUTIDE": 3.803648615338737, "SPIRONOLACTONE": 1.3583832182951552, "SPRYCEL": 1.078988458251104, "STIVARGA": 1.0270714893206263, "SUTENT": 1.8292583960373532, "TASIGNA": 1.3633406398631382, "TEDUGLUTIDE": 11.791425764328764, "TELMISARTAN": 1.743443210306645, "TICAGRELOR": 1.2223265249444455, "TOVIAZ": 1.3489225201944322, "TRACLEER": 1.9568605337689848, "TRESIBA": 1.1905722045128009, "TRIUMEQ": 1.9331064432690028, "TRULICITY": 6.419063795242743, "VELTASSA": 1.1000214640869244, "VEMLIDY": 4.0675649462136025, "VICTOZA": 4.147193277436177, "XALKORI": 1.240093759081429, "XELJANZ": 1.373024289152618, "XELODA": 1.7002613667813404, "ZEJULA": 2.6997288950118885, "null": 1.2474454258335952}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/100.json
index 654ada09b45..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/100.json
@@ -1 +1 @@
-{"BYETTA": 39.49797397591037, "SPIKEVAX": 1.522707257340836}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1000.json
index 2ed3a82a1b4..f94cca6c0f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1000.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1000.json
@@ -1 +1 @@
-{"null": 1.2519833288791404}
\ No newline at end of file
+{"CICLOSPORIN": 1.551093363976306, "CLOPIDOGREL": 3.003646984661253, "COMIRNATY": 0.5618620090267846, "CRIXIVAN": 28.06281448725047, "ELIQUIS": 5.638720305088707, "NOVOSEVEN": 55.73916270229012, "PLAVIX": 1.6229803477511684, "SPIKEVAX": 0.2570988326544607, "SUTENT": 0.7587209350685515, "TASIGNA": 5.012696767103374, "TOZINAMERAN": 0.2739453593062467, "VAXZEVRIA": 1.4090352259939587, "null": 0.7779317029878025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10000.json
new file mode 100644
index 00000000000..9bc2c6e415a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10000.json
@@ -0,0 +1 @@
+{"null": 1.481424803110106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10001.json
new file mode 100644
index 00000000000..97632c4a65a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10001.json
@@ -0,0 +1 @@
+{"null": 3.482047862237891}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10002.json
new file mode 100644
index 00000000000..b0af9301688
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10002.json
@@ -0,0 +1 @@
+{"null": 12.773112339438317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10003.json
new file mode 100644
index 00000000000..14e5325cb96
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10003.json
@@ -0,0 +1 @@
+{"AVASTIN": 22.27213658821236, "BEVACIZUMAB": 26.963045148026183, "COMIRNATY": 0.5234739578237659, "VAXZEVRIA": 0.6286132522729895, "null": 0.742379838672145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10004.json
new file mode 100644
index 00000000000..c8f0186ae40
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10004.json
@@ -0,0 +1 @@
+{"ADVAGRAF": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10005.json
new file mode 100644
index 00000000000..834055c00ef
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10005.json
@@ -0,0 +1 @@
+{"null": 0.6774515293431573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10006.json
new file mode 100644
index 00000000000..3eb51d8c4f1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10006.json
@@ -0,0 +1 @@
+{"AMIKACIN": 49.7260167254742, "STIVARGA": 14.51458307726868, "null": 0.7394223373919517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10007.json
new file mode 100644
index 00000000000..db47c14c9ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10007.json
@@ -0,0 +1 @@
+{"ABATACEPT": 1.3638648091385814, "ABILIFY": 1.9571560749031296, "ADCIRCA": 6.701267320435047, "AFINITOR": 1.2380337513566546, "ANORO": 2.913883770873646, "APIXABAN": 1.7823763678037094, "ARAVA": 3.164521806788984, "AVANDIA": 1.878490921952356, "BENLYSTA": 1.3386764472235262, "BUMETANIDE": 30.546038460782796, "BUPRENORPHINE": 4.3754424630309945, "CICLOSPORIN": 1.0444327409044416, "CLOPIDOGREL": 0.589634379262599, "COMIRNATY": 0.1508694207543613, "COSENTYX": 0.5076337830940343, "CYMBALTA": 0.602595457165847, "DULOXETINE": 1.709154438345473, "ELIQUIS": 0.4881013724914145, "EMPAGLIFLOZIN": 8.528371870009366, "ENTRESTO": 4.078697337071549, "FASENRA": 1.9519517957938255, "FENTANYL": 4.154797709035227, "GARDASIL": 0.2795915588515516, "IBRANCE": 0.7357314322031872, "IBUPROFEN": 0.9993504881244976, "INCRUSE": 10.464569005109356, "JAKAVI": 0.9725184753644442, "KEYTRUDA": 0.7169629964871778, "KYPROLIS": 4.6360577124864655, "LANTUS": 0.4601702948832265, "MEPOLIZUMAB": 2.03500240364784, "MULTAQ": 3.612147838508995, "NUCALA": 5.166053914677019, "OLANZAPINE": 6.1286943350854735, "OMALIZUMAB": 2.3896043423336053, "OPSUMIT": 4.968408846512941, "PANTOPRAZOLE": 2.639258865723499, "PEGINTRON": 1.3652034686346008, "PLAVIX": 0.9883477762139916, "REVATIO": 1.7516198164674233, "SHINGRIX": 0.5109685876105997, "SOLIRIS": 0.7417725708129325, "SPIKEVAX": 0.3367897253737674, "SPIRONOLACTONE": 5.502253863263049, "SPRYCEL": 2.073864447408475, "SUTENT": 0.1622115939920043, "SYNAGIS": 4.909881061699684, "TAMIFLU": 0.9766222078636398, "TOZINAMERAN": 0.6107853744712163, "TRACLEER": 3.4119826193508467, "TRELEGY": 12.502590078334284, "UMECLIDINIUM": 20.0200781157964, "VAXZEVRIA": 0.0740162620583765, "VIAGRA": 1.2256975945676096, "XELJANZ": 0.93878343520434, "XOLAIR": 6.035381876711719, "null": 1.5787953012967793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10008.json
new file mode 100644
index 00000000000..64e6540c01b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10008.json
@@ -0,0 +1 @@
+{"null": 1.1187061430061025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10009.json
new file mode 100644
index 00000000000..5362dc2227c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10009.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.0375072804255414, "ABILIFY": 0.9367034252542292, "ABRAXANE": 1.9152568636123255, "ACTOS": 0.5372362097336191, "ACTRAPID": 1.255880945651109, "ADALIMUMAB": 0.2083184408825423, "ADVAGRAF": 1.513352851537245, "AFINITOR": 0.8946042224353126, "AIMOVIG": 0.5575554499151112, "ALEMTUZUMAB": 0.3861468441006683, "ALIMTA": 1.690354492209511, "AMIKACIN": 0.7671629764764344, "AMINOSALICYLIC": 0.567209875284327, "ANAKINRA": 5.380179312431662, "ANORO": 7.344083260581602, "APIDRA": 0.1410714519572563, "APIXABAN": 3.053703760980751, "ARANESP": 0.628648737055007, "ARAVA": 0.0741122956800205, "ARIPIPRAZOLE": 0.2220175533333298, "ARIXTRA": 3.0498742035085766, "ASPARAGINASE": 1.0610555642709398, "ATAZANAVIR": 0.275501643863423, "ATRIPLA": 0.0104072606117146, "AUBAGIO": 0.4110999484305627, "AVANDAMET": 0.7571087587636456, "AVANDIA": 0.8332000935793786, "AVASTIN": 4.483784087047567, "AVELUMAB": 1.5745595700834036, "AXITINIB": 1.2149484155698125, "AZACITIDINE": 0.3624988336092279, 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2.609819612221366, "LONSURF": 0.5637682513237049, "LOPINAVIR": 0.8091826665586649, "LOXAPINE": 2.5113314247839105, "LYNPARZA": 1.0564912205010433, "LYRICA": 0.1944709612488362, "MABTHERA": 0.8242842081445033, "MEKINIST": 1.567190818949629, "MEPOLIZUMAB": 0.4319309772492896, "METFORMIN": 0.6122997465278621, "METHOTREXATE": 0.8127909099777222, "MICARDIS": 0.1446999603654954, "MIDAZOLAM": 0.2620697896690577, "MODERNA": 1.0097376276131305, "MVASI": 2.0226646515951123, "NEULASTA": 0.740075739691425, "NEXAVAR": 0.5122812571748913, "NOT": 0.3544819599550166, "NOVORAPID": 0.1402120373371889, "NOVOSEVEN": 16.17265945187263, "NOXAFIL": 0.5664769887552683, "NPLATE": 3.889300773120176, "NUCALA": 0.3224563007862732, "OCRELIZUMAB": 0.1883361215157159, "OFEV": 1.9471853272808, "OLANZAPINE": 2.331033351649644, "OLAPARIB": 1.496888717058475, "OLYSIO": 0.6425813132693123, "OMALIZUMAB": 0.4540918997898388, "ONCASPAR": 1.5839038833151504, "OPDIVO": 0.544856028559698, "OPSUMIT": 0.617451619153582, 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0.8537678991480627, "RUXOLITINIB": 0.5028438550953148, "SHINGRIX": 0.2289662575773726, "SIMPONI": 0.7340820011724818, "SKYRIZI": 1.4273212180903143, "SOLIRIS": 1.0892963100541009, "SOMAVERT": 5.5440660845432586, "SPIKEVAX": 0.8981021110611127, "SPRYCEL": 0.8313714040756998, "STELARA": 1.1084586170737898, "STIVARGA": 0.452347433874496, "SUBOXONE": 0.3007562573490898, "SUTENT": 0.9584829908543604, "SYCREST": 0.9082876161010076, "TAGRISSO": 3.061761150380486, "TAMIFLU": 0.122701140235649, "TASIGNA": 0.2665381724424506, "TEMODAL": 3.933902126670397, "TEMOZOLOMIDE": 1.7973037201836353, "TESTOSTERONE": 9.053819098044029, "THALIDOMIDE": 8.641650065482954, "TOCILIZUMAB": 1.1896358133586789, "TOFACITINIB": 5.458139007201937, "TORISEL": 1.0841098398776166, "TOZINAMERAN": 0.8726941562691469, "TRACLEER": 0.8570821619316956, "TRELEGY": 0.3781712795665737, "TREMFYA": 0.8167187194395233, "TRIUMEQ": 0.5906082522973296, "TRODELVY": 0.756209653317345, "TRULICITY": 0.2176667235653183, "TRUVADA": 0.0371870021202965, "UPADACITINIB": 5.712447604030968, "VAXZEVRIA": 1.5543965051747912, "VECTIBIX": 1.252736268119898, "VEKLURY": 0.8662899260735643, "VFEND": 0.1854765496377513, "VIAGRA": 0.3245267734922167, "VICTOZA": 0.3134631687609729, "VOTRIENT": 1.0622566974403571, "XALKORI": 3.251779859054128, "XARELTO": 4.876961422887843, "XELJANZ": 1.8929640428342485, "XOFIGO": 0.6515794564806983, "XOLAIR": 1.2729682122357848, "XTANDI": 0.3564305417875328, "YERVOY": 0.8216208353867495, "YESCARTA": 0.2885413022337592, "YONDELIS": 2.0523336845785307, "ZOSTAVAX": 0.3915739338815607, "ZYPADHERA": 0.847596904441029, "ZYPREXA": 2.1530327472684765, "null": 0.7960945611579433}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1001.json
index 7afe4e65e3c..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1001.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1001.json
@@ -1 +1 @@
-{"ABEMACICLIB": 6.925106015555614, "ACLIDINIUM": 13.905472518328969, "AFINITOR": 1.2315654542321488, "AGENERASE": 18.615332890126915, "ALOXI": 9.843290135730951, "APTIVUS": 17.35154857583515, "ASPARAGINASE": 5.86583937435927, "ATAZANAVIR": 10.424721826464426, "AVANDIA": 2.208542461144458, "AVASTIN": 1.175182306149608, "AXITINIB": 2.821920756991148, "AZACITIDINE": 1.1254053404457982, "AZATHIOPRINE": 1.600492290139525, "BARACLUDE": 4.681813342421798, "BEDAQUILINE": 2.5543675093740186, "BETAFERON": 1.567615907376938, "BEVACIZUMAB": 1.415581110153082, "BOSUTINIB": 4.059157401059607, "BUSULFAN": 3.486862881073948, "CANCIDAS": 6.821098364381569, "CAPECITABINE": 1.738823256139766, "CASPOFUNGIN": 5.071409616957467, "CELLCEPT": 1.7197782851538412, "CICLOSPORIN": 3.449422219636036, "COMBIVIR": 5.720541165596119, "COTELLIC": 2.102718310832065, "CRIXIVAN": 4.582089590566693, "CUBICIN": 1.1851269292837296, "CYTARABINE": 3.3476088037624203, "DACLATASVIR": 4.212472746770841, "DEFITELIO": 8.40632416116314, "DELAMANID": 4.261407411350907, "DEXAMETHASONE": 1.0411402876563929, "EBIXA": 2.2125006369891635, "EFAVIRENZ": 2.169721055902599, "EMTRICITABINE": 2.901572515512855, "EMTRIVA": 12.182984772246114, "ENTECAVIR": 5.079653263444774, "EPCLUSA": 4.663020411974359, "EPIVIR": 3.3208884934792406, "ERBITUX": 2.170288278862958, "ESOMEPRAZOLE": 1.1348823794204577, "EXJADE": 8.492450775917291, "EXVIERA": 35.93051297311714, "FASLODEX": 1.6994946127516426, "FASTURTEC": 9.020605055814965, "FULVESTRANT": 1.77077428960819, "GALVUS": 2.4439085118506894, "GLIVEC": 4.727285422385485, "HALAVEN": 1.010562645762734, "HARVONI": 4.98981893630443, "HEPSERA": 3.3453950080861063, "HERCEPTIN": 1.2697346731087105, "HUMAN": 1.2266823630156571, "HYCAMTIN": 2.9637077820045667, "IBUPROFEN": 1.5376037152670656, "IMATINIB": 1.5340240693756229, "INCIVO": 2.1171747402475107, "INTRONA": 1.4245721283942072, "IRINOTECAN": 1.571884344065, "ISENTRESS": 1.8512057282964407, "JAKAVI": 2.0635651738702587, "KAFTRIO": 11.870065083431642, "KALETRA": 3.004924032435068, "KISQALI": 5.722674809795118, "KIVEXA": 3.808926616883882, "KYMRIAH": 1.0386591687938371, "LAMIVUDINE": 2.4118946503528287, "LENVIMA": 5.396399218810838, "LEVOFLOXACIN": 1.5381528168301568, "LONSURF": 2.6460735743371093, "LOPINAVIR": 1.9685859539694417, "MABTHERA": 1.510605819101524, "MANNITOL": 6.658724086828021, "MAVENCLAD": 1.931876673164748, "MERCAPTOPURINE": 3.315554842848549, "MICARDIS": 1.7534496084194002, "MULTAQ": 6.128848835164764, "MYCAMINE": 7.456684090815462, "NEXAVAR": 11.522375727930156, "NILOTINIB": 10.102352696042926, "NORVIR": 9.56020195014718, "NOXAFIL": 3.69024215970927, "NUBEQA": 4.915613131664772, "OCALIVA": 30.106597693477987, "OFEV": 1.0060178397401174, "OLYSIO": 31.52470415886541, "ONCASPAR": 5.677846040567617, "OPSUMIT": 1.7437706618931106, "PAZOPANIB": 7.800948825404019, "PEGASYS": 2.3129320299976044, "PEGINTERFERON": 2.3208578132636024, "PEGINTRON": 2.3804710663731603, "POSACONAZOLE": 2.3390358965387645, "PRIVIGEN": 1.6384316523248807, "RASBURICASE": 11.154015452356177, "REBETOL": 4.853563273059305, "REMDESIVIR": 4.199809219536897, "REVOLADE": 8.652710491189472, "REYATAZ": 29.99183083400323, "RIBAVIRIN": 5.363175651413097, "RIBOCICLIB": 4.362074356800702, "ROACTEMRA": 1.2907313066979764, "RUBRACA": 1.1384211610197266, "RUXOLITINIB": 1.767574052705102, "SIMEPREVIR": 14.569413886960778, "SOLIRIS": 3.417550672733784, "SOTORASIB": 9.164748462552684, "SOVALDI": 7.412695506256812, "STIVARGA": 18.143605970705973, "SUTENT": 1.462032323878348, "TACROLIMUS": 1.5026272517177324, "TAMIFLU": 1.1737129851641246, "TASIGNA": 12.354251044771951, "TIGECYCLINE": 5.640249190247344, "TIVICAY": 1.8902035576474585, "TOPOTECAN": 4.701416267631148, "TRACLEER": 13.98380988349298, "TRODELVY": 1.1515702554447915, "TWINRIX": 1.0304041431965707, "VEKLURY": 2.126614091533756, "VENCLYXTO": 1.8894926384694368, "VFEND": 6.415889435040623, "VIRAMUNE": 5.303939711692982, "VORICONAZOLE": 2.3244721819495124, "VOTRIENT": 7.609380045347937, "XALKORI": 2.1730741132294216, "XELODA": 2.362730285734237, "YERVOY": 1.5057251926753807, "YONDELIS": 4.467904246632971, "ZELBORAF": 3.5236908294593285, "ZEPATIER": 3.230507347985777, "ZIAGEN": 2.7379674010269577, "null": 1.3236496515952287}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10010.json
new file mode 100644
index 00000000000..28e992af301
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10010.json
@@ -0,0 +1 @@
+{"OPSUMIT": 300.28204308032525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10011.json
new file mode 100644
index 00000000000..15fb076e1cd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10011.json
@@ -0,0 +1 @@
+{"CUBICIN": 497.9393578332279, "MEPOLIZUMAB": 19.22118185609669, "null": 2.4141518704002145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10012.json
new file mode 100644
index 00000000000..6c7cd8194aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10012.json
@@ -0,0 +1 @@
+{"ABATACEPT": 2.4149388750349767, "ADALIMUMAB": 5.0953028542528, "AFINITOR": 1.31647053436585, "ALIMTA": 2.1651331781184164, "AMINOSALICYLIC": 1.0862832304163204, "ANAKINRA": 7.993712524655476, "ANORO": 46.04009724517306, "APIXABAN": 7.02506369561232, "ARAVA": 2.688794797124445, "AVANDIA": 0.5145408032541487, "AVASTIN": 1.0400344351152269, "AZATHIOPRINE": 4.398464435583432, "BENLYSTA": 0.7300874905509712, "BRILIQUE": 0.7353268456000503, "BUDESONIDE": 6.524570934354902, "BUSULFAN": 0.6904853792457873, "BYETTA": 0.4390302965690764, "CELLCEPT": 3.00605712829682, "CHLORMETHINE": 31.862610923958854, "CIALIS": 4.237300140028569, "CICLOSPORIN": 0.3297961070403853, "CIMZIA": 1.3501656836121618, "COMIRNATY": 0.0591507628096235, "COSENTYX": 0.7204018938203041, "CYMBALTA": 0.4866423035024864, "CYTARABINE": 0.4366912109605802, "DEXAMETHASONE": 0.5142323806951348, "DOCETAXEL": 1.3191848143266367, "DOXORUBICIN": 1.8817513244626016, "ELIQUIS": 0.4726856467019957, "ENBREL": 3.015225721887317, "ESBRIET": 10.169314943310932, "EXFORGE": 1.139907773183974, "EXJADE": 0.5824073826290896, "FASENRA": 1.2756177931816226, "FASLODEX": 0.5401064504458216, "FIRDAPSE": 3.287769988996234, "FORSTEO": 1.1965344994266265, "GLIVEC": 2.498061624517764, "HERCEPTIN": 2.1951484717100342, "HUMALOG": 0.3830871488229071, "HUMIRA": 1.1606557368054315, "IBRANCE": 0.9671118179010222, "INCIVO": 1.330073280636188, "IRESSA": 2.571176689742857, "JANUMET": 1.163118235785669, "JANUVIA": 1.379617198195246, "KEPPRA": 0.1760074438946863, "KEYTRUDA": 0.9319153053331356, "LANTUS": 0.1506378377989454, "LEFLUNOMIDE": 2.838213403350176, "LYRICA": 1.3850781111594173, "MABTHERA": 5.333651518425477, "METHOTREXATE": 2.6304581231572906, "MICARDIS": 1.6789933496426583, "MULTAQ": 8.012815510561927, "NEULASTA": 1.900360934545795, "NEXAVAR": 0.2943135693414798, "NPLATE": 0.9449756616856476, "NUCALA": 1.8845561460418836, "OFEV": 10.79908655657334, "OLANZAPINE": 0.3431107686347855, "OPSUMIT": 1.7436955699026522, "OPTIMARK": 1.53010535377926, "PANTOPRAZOLE": 1.319383652914739, "PEGASYS": 1.190182422224959, "PEGINTERFERON": 1.679637935980256, "PEGINTRON": 1.4562645637864708, "PEMBROLIZUMAB": 2.343701687445632, "PLAVIX": 0.8570788807780397, "RAPAMUNE": 5.705139472265844, "REVATIO": 6.60847289045028, "RIBAVIRIN": 0.9971112256234468, "RINVOQ": 0.7088469147199781, "RITUXIMAB": 1.806676760662492, "ROACTEMRA": 2.313453030865216, "SHINGRIX": 0.2787490789660365, "SIMPONI": 1.0323590416787476, "SPIKEVAX": 0.0637944262417789, "STELARA": 0.761537673072132, "SUTENT": 0.2649909736926221, "TAGRISSO": 1.440647758918172, "TASIGNA": 0.8675554629793057, "TORISEL": 3.1487357653292696, "TOZINAMERAN": 0.1053151300963297, "TRACLEER": 5.972027503145929, "TRELEGY": 2.350258167574648, "VAXZEVRIA": 0.0339756006946556, "VFEND": 0.657847379374197, "XELJANZ": 2.2102969357954225, "XOLAIR": 0.4918810360116372, "ZOSTAVAX": 0.8237851391100826, "null": 1.606222759202436}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10013.json
new file mode 100644
index 00000000000..e962eab351c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10013.json
@@ -0,0 +1 @@
+{"ALENDRONATE": 555.3912433028696, "APIXABAN": 23.400966819978624, "AVAMYS": 21.705037768862503, "BUDESONIDE": 115.04014530067928, "COMIRNATY": 0.0422164221371834, "ELIQUIS": 1.146036447378869, "ENTRESTO": 5.357829792949751, "ESBRIET": 34.55818621173127, "MEPOLIZUMAB": 10.887217656256176, "NUCALA": 119.65099636851362, "null": 0.2963110572696117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10014.json
new file mode 100644
index 00000000000..e097ef52266
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10014.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 1.6513225336860715, "CELLCEPT": 1.8132444440509865, "CICLOSPORIN": 1.9747339975626068, "COMIRNATY": 0.3885630273663383, "ESBRIET": 29.515108095434044, "FASENRA": 21.714929745635786, "FENTANYL": 1.79459080853451, "KAFTRIO": 28.02499813926206, "KALYDECO": 190.13814207809693, "NUCALA": 5.464333052638083, "OFEV": 16.866008493366138, "OMALIZUMAB": 7.835922399951188, "ORKAMBI": 366.0563109608832, "PIRFENIDONE": 46.75724283173488, "SPIKEVAX": 0.1272529922988897, "TOBI": 166.51235418965229, "TRELEGY": 5.027332136716083, "VAXZEVRIA": 0.1315659286588535, "XOLAIR": 11.295100128559682, "null": 1.210939720275011}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10015.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10015.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10016.json
new file mode 100644
index 00000000000..3ac5a7357a5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10016.json
@@ -0,0 +1 @@
+{"IRBESARTAN": 33.05367305716744, "JANUMET": 11.627887569794746, "PEGASYS": 2.546950649512058, "SPIKEVAX": 0.3719577894948948, "null": 0.7032713700814729}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10017.json
new file mode 100644
index 00000000000..16fc3073cd5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10017.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 45.71872649689318, "null": 1.0117238947796094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10018.json
new file mode 100644
index 00000000000..6407da2f8d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10018.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 9.09943350663765, "AMIKACIN": 11.089191250638232, "AMINOSALICYLIC": 1.692571061133446, "ANGIOX": 62.2819798164794, "APIXABAN": 0.916133351455405, "ASPARAGINASE": 6.85738638256523, "AVASTIN": 2.306302203067307, "BEDAQUILINE": 5.979520117147652, "BRILIQUE": 8.158403992756023, "BRIVARACETAM": 17.43455959639538, "BUSULFAN": 10.833685167464573, "CELLCEPT": 1.8140914732674305, "CICLOSPORIN": 2.91503060076964, "CLOPIDOGREL": 8.592541123741503, "COMIRNATY": 0.0531011005849574, "CYTARABINE": 5.385205252880625, "DEFITELIO": 87.19483393321273, "DEXAMETHASONE": 5.057718222039113, "ELIQUIS": 5.986500817145729, "ENOXAPARIN": 5.888996357594936, "FEBUXOSTAT": 15.529225430457023, "FENTANYL": 2.598923430401069, "INTEGRILIN": 40.508386290727714, "JAKAVI": 1.9519993005999892, "KAFTRIO": 7.277039496858859, "KEYTRUDA": 1.0828072824439, "NEXAVAR": 0.7714506650531628, "NOVOSEVEN": 16.943045039242946, "NPLATE": 4.167726210467282, "OPSUMIT": 2.5587902781767435, "PLAVIX": 5.627381722238279, "RAPAMUNE": 6.99616499210777, "REVATIO": 2.8356317966961444, "SOLIRIS": 6.177247818407656, "SPIKEVAX": 0.0645361220380341, "SUTENT": 1.768281440892974, "TICAGRELOR": 14.73140373657302, "TRACLEER": 5.261708859275798, "VAXZEVRIA": 0.089391544391376, "VFEND": 3.072916918495556, "VOTRIENT": 2.8514412085888394, "XARELTO": 8.910864175538967, "XELJANZ": 0.4064930266358391, "null": 1.1224516258802653}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10019.json
new file mode 100644
index 00000000000..03e6aa80ef8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10019.json
@@ -0,0 +1 @@
+{"null": 4.045079320151362}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1002.json
index 596210d40fb..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1002.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1002.json
@@ -1 +1 @@
-{"SPIKEVAX": 52.301057913101545}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10020.json
new file mode 100644
index 00000000000..c358436bf86
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10020.json
@@ -0,0 +1 @@
+{"null": 0.358317703186629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10021.json
new file mode 100644
index 00000000000..753ec05e81b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10021.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.454946001173915, "ADCIRCA": 17.367461238321393, "ADEMPAS": 15.367376900273689, "AFINITOR": 0.4017697649970728, "AMBRISENTAN": 23.393007946377143, "ANAKINRA": 1.3200401007269624, "APIXABAN": 0.7350096337314945, "ARAVA": 0.1144598743594104, "AVANDAMET": 4.95285884304413, "AVANDIA": 7.998518804061009, "BEDAQUILINE": 2.5720151919328944, "BENLYSTA": 0.6646939949772366, "BORTEZOMIB": 2.7486597628446803, "BOSENTAN": 35.76278630176294, "BOSULIF": 10.091001338829225, "BOSUTINIB": 11.291134283732966, "BUMETANIDE": 3.4243357696157606, "BUSULFAN": 6.152317406385167, "CARFILZOMIB": 7.909881017508173, "CELLCEPT": 1.4295379717904635, "CICLOSPORIN": 0.4603258482320607, "CLOPIDOGREL": 0.6461752879787093, "COMIRNATY": 0.0751494372845869, "CUBICIN": 1.4543443655089496, "CYMBALTA": 0.3705537430239947, "CYTARABINE": 0.4927564147432429, "DAPAGLIFLOZIN": 4.894571905108378, "DASATINIB": 19.216775396516987, "DEXAMETHASONE": 0.9818239624049446, "DOCETAXEL": 0.8363815198441731, "ELIQUIS": 1.0268039270275269, "ENTRESTO": 3.667162414004477, "EPIVIR": 3.183165601144518, "ESBRIET": 4.034309557336277, "ESOMEPRAZOLE": 2.538660839197544, "EXJADE": 2.266171219091458, "FASLODEX": 0.6094573411081918, "FENTANYL": 0.9745414968466788, "FORSTEO": 0.3201948915227504, "GANCICLOVIR": 2.3506556572309822, "GLIVEC": 3.956278344060807, "HERCEPTIN": 1.596354844335064, "HUMALOG": 0.2775998909754454, "IBRANCE": 0.213401326736609, "ICLUSIG": 4.181125461880895, "INVIRASE": 6.968597543299654, "IRON": 3.700827929861738, "JAKAVI": 5.021567313279503, "JARDIANCE": 0.5656166481504724, "KYPROLIS": 26.788262446063747, "LIXIANA": 1.8156546928390864, "LYRICA": 0.6006917398128122, "MACITENTAN": 34.204404234736465, "MELPHALAN": 6.042918517704777, "MICARDIS": 1.3845763599084322, "MULTAQ": 1.632452442966656, "NAGLAZYME": 12.240760215941242, "NILOTINIB": 6.39518956726823, "NPLATE": 1.350914159559944, "OFEV": 8.38786401808802, "OPSUMIT": 31.73413759343223, "OPTIMARK": 0.9232274412097964, "PEGASYS": 0.9999724939214186, "PEGINTRON": 1.1783950330434692, "PLAVIX": 0.241860074915988, "REBETOL": 2.5768268485475616, "REVATIO": 100.21136138757144, "RIOCIGUAT": 102.00807033669888, "SILDENAFIL": 25.660831726918104, "SOLIRIS": 1.7847764932946748, "SPIKEVAX": 0.0888820930733477, "SPRYCEL": 36.72715378548201, "STELARA": 0.4639966900210188, "SUTENT": 0.1820467447898559, "SYNAGIS": 5.552956579381494, "TAGRISSO": 1.0543888352114748, "TASIGNA": 2.275414375557695, "THALIDOMIDE": 2.786863653378804, "TOBRAMYCIN": 4.374604381434981, "TOZINAMERAN": 0.0760673838809094, "TRACLEER": 49.42326982649671, "TRACTOCILE": 24.30728274357121, "TRELEGY": 0.8271461550190802, "VAXZEVRIA": 0.035537490870647, "VIAGRA": 4.155967594779621, "XELJANZ": 0.657282394344697, "XOLAIR": 0.7613613305624203, "ZOSTAVAX": 1.1216328451909672, "ZYPREXA": 0.4970639094029303, "null": 0.8961479715241178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10022.json
new file mode 100644
index 00000000000..c5efe751a0c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10022.json
@@ -0,0 +1 @@
+{"MIDAZOLAM": 82.22632099169203, "SILDENAFIL": 154.8397607935615, "TRACLEER": 157.9687662366876, "null": 0.2227338004811896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10023.json
new file mode 100644
index 00000000000..f3334cca111
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10023.json
@@ -0,0 +1 @@
+{"MICARDIS": 33.597946141138486, "null": 3.3601769526731515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10024.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10024.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10025.json
new file mode 100644
index 00000000000..96224049692
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10025.json
@@ -0,0 +1 @@
+{"ACTRAPID": 53.37005354475439, "COMIRNATY": 1.339683771666654, "ELIQUIS": 1.262148780779234, "SPIKEVAX": 1.0236247180352118, "TOZINAMERAN": 0.6648518361489589, "VAXZEVRIA": 1.1659042735555918, "ZYPREXA": 2.2766425526113023, "null": 0.8494314840161333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10026.json
new file mode 100644
index 00000000000..979462817b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10026.json
@@ -0,0 +1 @@
+{"null": 3.888684653270179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10027.json
new file mode 100644
index 00000000000..5eccd0fcd6e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10027.json
@@ -0,0 +1 @@
+{"null": 4.061925730769543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10028.json
new file mode 100644
index 00000000000..73ba622168e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10028.json
@@ -0,0 +1 @@
+{"ABRAXANE": 23.2670822950978, "ACLIDINIUM": 9.542625971180897, "ADALIMUMAB": 0.7222622344478695, "AFINITOR": 5.010346545702173, "ALIMTA": 1.3961495722791586, "AMIKACIN": 5.923889203078185, "ANORO": 2.2727299723518404, "APIXABAN": 0.4890408806118441, "ARAVA": 2.499158986894849, "AVAMYS": 7.129125920356038, "AVASTIN": 1.7772768088402264, "AXITINIB": 3.929755940829143, "AZATHIOPRINE": 3.330459350855796, "BENLYSTA": 1.044126969354095, "BENRALIZUMAB": 6.740545125336133, "BEVACIZUMAB": 1.5356912941783247, "BUDESONIDE": 8.880624013407303, "BUPRENORPHINE": 1.655075102299591, "BYETTA": 7.945015212628883, "CABOMETYX": 2.655555117196493, "CAPECITABINE": 4.213353277376842, "CASPOFUNGIN": 6.206885209668884, "CELLCEPT": 0.7821372821787925, "CICLOSPORIN": 3.128172674049954, "CIMZIA": 1.3245628401046594, "CLOFARABINE": 15.478337669749374, "COMIRNATY": 0.069864327749684, "COSENTYX": 1.1951023609878615, "CYMBALTA": 0.5205473632022515, "CYTARABINE": 3.13730654094062, "DABRAFENIB": 6.528449299665128, "DEXAMETHASONE": 1.3069765449523176, "DOCETAXEL": 2.9177652190086456, "DULOXETINE": 4.304011357253837, "ELIQUIS": 0.4956769895970435, "ENBREL": 2.174711136073681, "ENTRESTO": 0.5617949667867344, "ENTYVIO": 1.3325622810088282, "FASENRA": 2.1914141895990418, "FASLODEX": 2.8399964324246088, "FIRDAPSE": 7.148871893842365, "FULVESTRANT": 5.036649763590992, "GARDASIL": 0.3061295421636669, "GEFITINIB": 6.943093835059006, "GLYCOPYRRONIUM": 16.43957354278706, "HUMALOG": 0.4251863885622599, "HUMIRA": 1.3641183583931862, "IBRANCE": 2.181105469812254, "IBUPROFEN": 1.5376484109970776, "INLYTA": 1.2321627488494633, "INSULIN": 2.909853517320088, "IPILIMUMAB": 2.518144752577629, "IRESSA": 3.188748393657633, "IRINOTECAN": 3.7491853002540503, "JAKAVI": 2.019084831100026, "JANUMET": 8.059404802022135, "JANUVIA": 6.848373101185476, "KEYTRUDA": 1.6663312042152336, "KISQALI": 2.3870699690185435, "LANTUS": 0.3704216445470398, "MEKINIST": 2.807526969748478, "MEPOLIZUMAB": 9.732759694776211, "METHOTREXATE": 1.905844307726904, "MYCOPHENOLATE": 3.2598455729153497, "NEULASTA": 1.6915696385935175, "NEXAVAR": 2.852158342263045, "NOXAFIL": 4.456824297816995, "NUCALA": 6.687326595817944, "OMALIZUMAB": 0.7249580299292616, "OPSUMIT": 0.9646189832863612, "PAZOPANIB": 4.235672980853655, "PEGASYS": 1.2746266526790728, "PEGINTRON": 0.9726292578229208, "PEMBROLIZUMAB": 1.74016825473474, "PLAVIX": 0.4624067347796684, "RIBOCICLIB": 5.1817882879946335, "RINVOQ": 0.99164854619785, "RITUXIMAB": 1.2824859524792738, "SIMPONI": 1.5174735847198302, "SPIKEVAX": 0.201573142161913, "STELARA": 1.1129308482772549, "STIVARGA": 2.998664571389495, "SUTENT": 1.6487924538361842, "TAGRISSO": 2.911086503171793, "TOZINAMERAN": 0.1980285615932331, "TRELEGY": 6.803645507795789, "TRULICITY": 0.8417345945396086, "VAXZEVRIA": 0.0401827794447024, "VFEND": 0.8225571162390081, "VORICONAZOLE": 4.282430518265219, "VOTRIENT": 4.092971664586369, "XELJANZ": 2.1886254155836475, "XOLAIR": 3.007078089172426, "ZOSTAVAX": 3.502273027625037, "null": 0.6331222332252407}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10029.json
new file mode 100644
index 00000000000..d16915cb8d8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10029.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3843819800197352, "null": 2.805853187951373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1003.json
index 09eab82190a..a1f70ae9a07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1003.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1003.json
@@ -1 +1 @@
-{"CYTARABINE": 12.071573834927326, "EXJADE": 6.156810747961655, "KAFTRIO": 25.482286294343577, "KALETRA": 16.717448987301786, "REYATAZ": 91.59487959699156, "ROACTEMRA": 8.625370382212012, "TASIGNA": 16.73196857723267, "null": 1.0312028854936863}
\ No newline at end of file
+{"null": 1.6950053364439617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10030.json
new file mode 100644
index 00000000000..ab1dd257387
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10030.json
@@ -0,0 +1 @@
+{"MYCOPHENOLATE": 94.65333735805204, "VORICONAZOLE": 127.70810980739692, "null": 0.2665945559457354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10031.json
new file mode 100644
index 00000000000..060d30c36ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10031.json
@@ -0,0 +1 @@
+{"null": 0.7670283829336809}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10032.json
new file mode 100644
index 00000000000..94ba60fc671
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10032.json
@@ -0,0 +1 @@
+{"FASENRA": 152.6776725873966, "null": 0.2638364935603558}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10033.json
new file mode 100644
index 00000000000..6559acfc779
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10033.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.3315801083055889, "ACTOS": 5.1786890260967535, "ADCIRCA": 8.874527907168225, "ADEMPAS": 2.947523623401387, "AFINITOR": 1.2172727810597128, "ALEMTUZUMAB": 0.6314447536633356, "ALIMTA": 1.002912807771425, "AMBRISENTAN": 2.965118152980926, "AMIKACIN": 1.1821275295065974, "APIDRA": 0.5028059112682296, "APIXABAN": 0.3765280171570325, "APROVEL": 0.8461047954064305, "ARANESP": 0.6610261963936154, "ARAVA": 0.0739647997898052, "ARIPIPRAZOLE": 0.2473062940282558, "ASENAPINE": 24.87733847429288, "ATOSIBAN": 4.591047642145907, "ATRIPLA": 0.0322289101980157, "AVAMYS": 1.4896469867657471, "AVANDAMET": 7.573494377602544, "AVANDIA": 10.48716253994342, "AVASTIN": 0.3283184369948982, "AZACITIDINE": 0.8949996874222322, "AZATHIOPRINE": 0.4516022983971046, "BEDAQUILINE": 2.300310554403805, "BENLYSTA": 0.2993866503255183, "BORTEZOMIB": 4.260994729700002, "BOSENTAN": 8.244730395300698, "BOSULIF": 10.764792796666097, "BRIDION": 8.726714111525514, "BRILIQUE": 1.6320105108776684, "BUDESONIDE": 0.1625711629341602, "BUMETANIDE": 1.9539879895706145, "BUPIVACAINE": 1.1024336756387814, "BUPRENORPHINE": 3.321221564743533, "BUSULFAN": 1.050190501226353, "BYETTA": 0.406671102711075, "CABOMETYX": 0.3776690852512511, "CAPECITABINE": 0.5439428684107778, "CARFILZOMIB": 3.373550944249354, "CELECOXIB": 0.9223720938792522, "CELLCEPT": 1.2911749170903626, "CHAMPIX": 0.2055549295298203, "CICLOSPORIN": 0.9195044582584954, "CIMZIA": 0.1757370123965557, "CLOPIDOGREL": 1.2469219053414269, "COMIRNATY": 0.1447449991198864, "COSENTYX": 0.3157951517959969, "CUBICIN": 0.8298507655543872, "CYMBALTA": 0.0986189774359144, "CYTARABINE": 1.602979827515985, "DAPAGLIFLOZIN": 7.934219779640464, "DARZALEX": 1.5236757871359898, "DEXAMETHASONE": 1.9162464982445109, "DOCETAXEL": 0.2973705497096446, "DULOXETINE": 1.827421295670626, "ELIQUIS": 1.55959893780363, "ENBREL": 0.1611921665248087, "ENOXAPARIN": 1.0577100356331277, "ENTRESTO": 3.815012638596467, "EPIVIR": 1.1779960883758764, "ESBRIET": 2.9301475046574064, 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0.6470697669191191, "JANUMET": 0.3493548003528718, "JANUVIA": 0.6152004975854809, "JARDIANCE": 0.7491238054751311, "KALETRA": 1.5710417249338493, "KEPPRA": 0.1886465349496046, "KEYTRUDA": 0.7243888872665992, "KISQALI": 0.765838463321036, "KYMRIAH": 1.6342021998234064, "KYPROLIS": 7.657442046480595, "LANTUS": 0.9592406160451988, "LEMTRADA": 0.7034981594448121, "LEVEMIR": 0.8686828515543421, "LEVETIRACETAM": 0.4268292213720586, "LEVOFLOXACIN": 0.5226732721545336, "LYRICA": 0.5754168167942512, "MACITENTAN": 11.202686820306052, "MEKINIST": 1.1168616548592532, "MEPOLIZUMAB": 0.3294689854449834, "METHOTREXATE": 0.7610421464991847, "MICARDIS": 0.9116229460038398, "MIDAZOLAM": 2.899131160840824, "MIMPARA": 1.237359746797473, "MIRCERA": 2.248599058525283, "MULTAQ": 3.857376190703645, "NAGLAZYME": 2.429627327010325, "NALOXONE": 8.184674553034494, "NEXAVAR": 0.3533237409413832, "NOVORAPID": 0.3538789625451516, "NOVOSEVEN": 2.61511181731344, "NPLATE": 0.4803067274591028, "NUCALA": 0.8756053601404598, "OFEV": 0.5278216681244873, "OLANZAPINE": 1.324941766088369, "OLYSIO": 1.0352590786719489, "OPDIVO": 0.455749041617107, "OPSUMIT": 7.696881425543332, "OPTIMARK": 0.7029772537778374, "PEGASYS": 0.6111527945619039, "PEGINTRON": 0.8092424433478766, "PLAVIX": 0.7571444754720269, "PREGABALIN": 0.6327242775371006, "PRIVIGEN": 1.5827212150564174, "RAPAMUNE": 1.8549727398151343, "RASILEZ": 2.349717784580712, "RELVAR": 1.156824869450306, "REVATIO": 5.421716243309108, "REVLIMID": 1.2106402007721666, "RINVOQ": 0.5349348672490113, "ROACTEMRA": 0.5284736720351413, "SILDENAFIL": 5.906138990817183, "SIMPONI": 0.6015244921260837, "SOLIRIS": 2.056905172934631, "SPIKEVAX": 0.1866948451285323, "SPIRONOLACTONE": 2.291952274525096, "SPRYCEL": 35.807546041200844, "STELARA": 0.2668830660328304, "SUBOXONE": 0.7138860991947102, "SUTENT": 2.313770840339474, "SYNAGIS": 0.6043156082280438, "TAGRISSO": 2.7454816572585274, "TAMIFLU": 0.4935106934236256, "TASIGNA": 2.1490143394567154, "TORISEL": 2.302386819844626, "TOVIAZ": 0.6190481950074689, "TOZINAMERAN": 0.3104870435885321, "TRACLEER": 5.328578210636702, "TRACTOCILE": 44.54136136343621, "TRELEGY": 2.698971519573068, "VALSARTAN": 2.102668079936036, "VAXZEVRIA": 0.080414430397837, "VELTASSA": 4.812157422565927, "VFEND": 1.1115567673240077, "VIAGRA": 0.9449675998596428, "VIRAMUNE": 2.8201162941153752, "VOTRIENT": 1.2758822612097425, "XALKORI": 4.487361241282023, "XARELTO": 0.6205192209399303, "XELJANZ": 0.8799979150165467, "XOLAIR": 0.5159871561175777, "XTANDI": 0.6465602053284226, "YESCARTA": 0.806630415036117, "ZOSTAVAX": 0.2840368009793404, "ZYPREXA": 1.0261730812935124, "null": 1.5659946060339998}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10034.json
new file mode 100644
index 00000000000..f7f0b195b01
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10034.json
@@ -0,0 +1 @@
+{"null": 34.29733529043406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10035.json
new file mode 100644
index 00000000000..e99cd185e39
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10035.json
@@ -0,0 +1 @@
+{"BENLYSTA": 2.634514958563839, "COMIRNATY": 2.945199896537581, "ENBREL": 4.150344048008377, "ESBRIET": 2.864463701596189, "FASENRA": 3.2044042328476188, "HUMIRA": 3.317677667088817, "IBRANCE": 0.6367640691213432, "KAFTRIO": 3.698830111308748, "MEPOLIZUMAB": 1.3896050607201098, "NUCALA": 1.8376391391275289, "OPSUMIT": 1.1805171768049547, "SPIKEVAX": 2.2230210246420308, "TOZINAMERAN": 2.737885444071809, "TRELEGY": 3.932391688170632, "VAXZEVRIA": 2.7103256645219425, "XELJANZ": 0.9187645651614682, "null": 0.2508804815288527}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10036.json
new file mode 100644
index 00000000000..439c968904e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10036.json
@@ -0,0 +1 @@
+{"DOCETAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10037.json
new file mode 100644
index 00000000000..c12d274b236
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10037.json
@@ -0,0 +1 @@
+{"null": 1.308269228709178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10038.json
new file mode 100644
index 00000000000..e357fc21fcd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10038.json
@@ -0,0 +1 @@
+{"null": 4.03230985466176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10039.json
new file mode 100644
index 00000000000..7ac3f7d6bfa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10039.json
@@ -0,0 +1 @@
+{"ANORO": 132.97758905116666, "null": 1.065215303527589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1004.json
index 2964343b296..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1004.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1004.json
@@ -1 +1 @@
-{"BIKTARVY": 8.257055944504613, "CLOPIDOGREL": 1.628495267051692, "COVID19": 1.4195124848833915, "ELIQUIS": 4.001715132464055, "NPLATE": 15.059613537086902, "PEGASYS": 1.8465895348851704, "PLAVIX": 1.9995861277928415, "SUTENT": 3.5004321521275648, "TOZINAMERAN": 1.0699120744438757, "XELJANZ": 1.1651343377965742, "null": 1.0829745127688288}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10040.json
new file mode 100644
index 00000000000..d0da7a58d9e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10040.json
@@ -0,0 +1 @@
+{"ARAVA": 1.4328186372706422, "CIMZIA": 4.116729663645673, "COMIRNATY": 0.3493136121221518, "KEYTRUDA": 6.5257167053251335, "PEGASYS": 8.894496582030062, "PEGINTERFERON": 44.70135045759712, "PEGINTRON": 8.498278330957756, "SIMPONI": 8.972081263787974, "null": 0.270959740480144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10041.json
new file mode 100644
index 00000000000..6c4bdb17132
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10041.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1464498155149085, "ELIQUIS": 3.944396943799364, "null": 0.639277439638116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10042.json
new file mode 100644
index 00000000000..556b0c0ec3b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10042.json
@@ -0,0 +1 @@
+{"null": 0.9062558297406124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10043.json
new file mode 100644
index 00000000000..f2f3bcac596
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10043.json
@@ -0,0 +1 @@
+{"VIRAMUNE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10044.json
new file mode 100644
index 00000000000..c011867b8f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10044.json
@@ -0,0 +1 @@
+{"ANAKINRA": 55.85209685346519, "CIMZIA": 1.020481446165824, "COMIRNATY": 0.2933384935213276, "ELIQUIS": 7.26675020418226, "ENBREL": 1.4820410050519557, "ESBRIET": 4.370560536414549, "EVISTA": 4.559255692432718, "FASLODEX": 1.7555755030144544, "HUMALOG": 0.5872708669819249, "HUMIRA": 1.0693550860005274, "IBRANCE": 8.37846341871662, "INLYTA": 2.2595050961575143, "JARDIANCE": 0.5471733557820707, "KEYTRUDA": 0.5860224168511409, "LYRICA": 3.140868460168761, "METHOTREXATE": 1.178137184475367, "MISOPROSTOL": 50.67295901262548, "OMALIZUMAB": 6.217827858317635, "OPSUMIT": 2.932123591514781, "PEGASYS": 0.3377272509011115, "PEGFILGRASTIM": 17.390031690283337, "PLAVIX": 0.4961605466782067, "REVATIO": 4.929919761129982, "REVLIMID": 6.988043949799658, "RINVOQ": 3.466796007833671, "SPIKEVAX": 0.7367840704405688, "STELARA": 1.0792680590939203, "SUTENT": 1.884541646886509, "TOZINAMERAN": 2.9183628753895667, "TRELEGY": 2.3398603130346225, "VAXZEVRIA": 0.613076064134492, "VIAGRA": 1.9262275783006728, "VOTRIENT": 2.405848850274854, "XALKORI": 4.601415207929729, "XARELTO": 5.562793845876686, "XELJANZ": 4.894234048440405, "XOLAIR": 1.5775729595065155, "XTANDI": 1.0722629039497034, "null": 0.8572824026338648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10045.json
new file mode 100644
index 00000000000..022dc11ace6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10045.json
@@ -0,0 +1 @@
+{"ABATACEPT": 1.6947999816971613, "ADALIMUMAB": 0.44956354875733, "AFINITOR": 4.730866619484466, "ALIMTA": 4.386769903852649, "ARAVA": 8.333437664968427, "BEVACIZUMAB": 4.825233068341156, "BUSULFAN": 2.652808012912645, "CARMUSTINE": 8.267271925146948, "CIMZIA": 1.91847312122098, "CLOPIDOGREL": 0.5230977109665973, "CUBICIN": 6.436333795181152, "DEXAMETHASONE": 1.1748258941256575, "DOXORUBICIN": 3.965623405448583, "ENBREL": 8.968469862417994, "ENTYVIO": 3.493734622774224, "IBRANCE": 1.5809653266073136, "IPILIMUMAB": 5.0893657882930885, "IRESSA": 6.662793842786507, "KEYTRUDA": 9.430856986995682, "LEFLUNOMIDE": 5.852073812441962, "LYNPARZA": 2.831017124228476, "MEKINIST": 1.5402377381457877, "METHOTREXATE": 2.1067961956225303, "MIDAZOLAM": 2.897872365273095, "MULTAQ": 8.409473394434361, "NEULASTA": 6.231656427254602, "OPDIVO": 15.986156831300322, "PEMBROLIZUMAB": 8.068596274511483, "PEMETREXED": 7.914760144598592, "RITUXIMAB": 10.926416862664292, "TAGRISSO": 63.23391072785357, "VECTIBIX": 12.159814541873336, "null": 1.4024742275751665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10046.json
new file mode 100644
index 00000000000..af13f95535b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10046.json
@@ -0,0 +1 @@
+{"ABACAVIR": 4.683215957035845, "ADALIMUMAB": 0.6593903238474497, "AMINOSALICYLIC": 37.58363606480747, "ARAVA": 0.6041338279090901, "BEDAQUILINE": 59.616926898268304, "CELLCEPT": 11.189429596879986, "CICLOSPORIN": 7.798180270125339, "CIMZIA": 3.239175881053755, "COMBIVIR": 9.36722900056363, "COMIRNATY": 0.0837901444822579, "DELAMANID": 20.908291992416935, "DEXAMETHASONE": 2.6530379537710003, "EFAVIRENZ": 16.97020560875137, "HUMIRA": 4.383475672448549, "INFLIXIMAB": 18.702202370765622, "JAKAVI": 9.13927380027386, "KALETRA": 9.929214700693889, "KEYTRUDA": 1.864132449279968, "LAMIVUDINE": 11.216014152130064, "LEVOFLOXACIN": 4.924636436529361, "METHOTREXATE": 5.989371586418247, "MYCOPHENOLATE": 9.78638286146358, "NEXAVAR": 2.0155529752909755, "PEGASYS": 2.913748357730022, "PEGINTERFERON": 9.361609573384415, "PEGINTRON": 3.2402997459025897, "REMICADE": 12.228488732351382, "ROACTEMRA": 6.056390365464915, "RUXOLITINIB": 14.872243484455126, "SIMPONI": 20.243695058917236, "SIRTURO": 70.57367086101097, "STELARA": 1.1730599970579736, "TREMFYA": 6.424505021479531, "null": 0.5845690613971791}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10047.json
new file mode 100644
index 00000000000..e2849ddce9f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10047.json
@@ -0,0 +1 @@
+{"CYMBALTA": 28.80605927402258, "null": 0.5545908350269357}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10048.json
new file mode 100644
index 00000000000..26f85a24756
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10048.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 49.94088352231433, "COMIRNATY": 0.1365086838511696, "null": 2.0737079682447668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10049.json
new file mode 100644
index 00000000000..314e55022cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10049.json
@@ -0,0 +1 @@
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1005.json
index 5badf4752bb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1005.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1005.json
@@ -1 +1 @@
-{"CAPRELSA": 2023.5237525885243}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10050.json
new file mode 100644
index 00000000000..821201f9372
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10050.json
@@ -0,0 +1 @@
+{"ISENTRESS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10051.json
new file mode 100644
index 00000000000..bfb20985bce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10051.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 40.59039606917415, "KEPPRA": 3.267486369505759, "null": 7.217907337983956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10052.json
new file mode 100644
index 00000000000..6fc85fc7c3d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10052.json
@@ -0,0 +1 @@
+{"null": 13.436489546152847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10053.json
new file mode 100644
index 00000000000..b9332a3720b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10053.json
@@ -0,0 +1 @@
+{"METHOTREXATE": 20.1561043239718, "MIDAZOLAM": 73.88885032846771, "null": 0.9378442589214228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10054.json
new file mode 100644
index 00000000000..ad02454995d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10054.json
@@ -0,0 +1 @@
+{"LYRICA": 189.40649565766608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10055.json
new file mode 100644
index 00000000000..e7bc8d28229
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10055.json
@@ -0,0 +1 @@
+{"ANORO": 1051.319867986339, "APIXABAN": 98.64336981947288, "AZATHIOPRINE": 62.81142884676834, "HUMIRA": 12.091787183714588, "null": 0.1827448522903228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10056.json
new file mode 100644
index 00000000000..5b06f1dfb31
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10056.json
@@ -0,0 +1 @@
+{"BUSULFAN": 113.45779562216876, "OPSUMIT": 50.87624731714959, "TRACLEER": 23.360554708260626, "null": 0.9516457478709924}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10057.json
new file mode 100644
index 00000000000..b2ab27db4d1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10057.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.6615872322303011, "ELIQUIS": 3.148486595723456, "ROACTEMRA": 25.17143602732152, "SPIKEVAX": 0.6254600790776457, "SUTENT": 1.71689256577298, "VAXZEVRIA": 0.3118131966722449, "null": 0.3251016724825632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10058.json
new file mode 100644
index 00000000000..5057228c58a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10058.json
@@ -0,0 +1 @@
+{"ATRIPLA": 6.945347866172387, "null": 1.022072236146629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10059.json
new file mode 100644
index 00000000000..7fcf3819c9c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10059.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.4933609412424458, "GARDASIL": 1.9182632482901625, "JANUMET": 2.4061764889428754, "NIMENRIX": 3.518928172618143, "SPIKEVAX": 0.9821789964679684, "SUBOXONE": 1.8931567836813292, "TOZINAMERAN": 1.067770037402804, "TWINRIX": 5.638753836212602, "VAXZEVRIA": 1.1022237321374442, "ZOSTAVAX": 1.291581034790639, "null": 1.2459343901634914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1006.json
index 356594eb8a3..0aaf06c4ed1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1006.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1006.json
@@ -1 +1 @@
-{"FORSTEO": 11.403199381818732, "IRBESARTAN": 24.73191768451817, "MIMPARA": 155.49474724300757, "SUTENT": 2.5777052270661347, "ZOSTAVAX": 4.667163838601329, "null": 1.728735975260394}
\ No newline at end of file
+{"AMINOSALICYLIC": 1.2704060955385224, "ANORO": 94.04125245024495, "APIXABAN": 12.279589019510942, "ARANESP": 1.2492663459838786, "AVANDAMET": 44.49856676448125, "AVANDIA": 29.9932414377477, "AZATHIOPRINE": 6.046876709575552, "BOSULIF": 3.1740392819132848, "BRILIQUE": 1.6377019699692346, "BUDESONIDE": 0.5680622999391779, "BUPRENORPHINE": 0.855306513887117, "BYETTA": 5.57568813475133, "CICLOSPORIN": 2.2974106702995, "CLOPIDOGREL": 1.8255863972534887, "COMIRNATY": 0.1727828115964069, "CYMBALTA": 0.5122797782385806, "DOCETAXEL": 1.1506372405313765, "DULOXETINE": 1.8337723885545327, "ELIQUIS": 1.1602245476464224, "ENTRESTO": 1.94040861919125, "EXFORGE": 1.8967387768281392, "EXJADE": 1.1459130390432826, "FORSTEO": 1.341335560583472, "HUMALOG": 1.7733302268920643, "IBRANCE": 0.3284761917132068, "IBUPROFEN": 1.3051388062523837, "ICLUSIG": 6.599810202144397, "INSULIN": 1.6201927813223194, "JANUMET": 5.584793707089239, "JANUVIA": 4.084677463673096, "KALETRA": 1.2995209122476847, "KEYTRUDA": 0.727042928487816, "LANTUS": 0.7366833325611725, "NILOTINIB": 8.397776624493467, "OPTIMARK": 2.02031240214266, "PLAVIX": 1.1727710402902518, "PREGABALIN": 3.525741811301765, "RINVOQ": 1.2311797215122495, "ROSIGLITAZONE": 25.98107655929585, "SPIKEVAX": 0.1295585786888309, "SPRYCEL": 1.3813826141822825, "STELARA": 0.4856883476409965, "SUBOXONE": 0.6326313798717328, "SUTENT": 0.4439674759027592, "TASIGNA": 80.4511118495703, "TESTOSTERONE": 10.676505452687696, "TOZINAMERAN": 0.188459389705146, "TRUVADA": 0.1899039918584948, "VAXZEVRIA": 0.0870126237994617, "VIAGRA": 0.9367752052181952, "XELJANZ": 0.3866094538753204, "ZOMETA": 9.835765219158038, "ZOSTAVAX": 3.138886773829273, "ZYPREXA": 0.926724630826242, "null": 0.8513508795838673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10060.json
new file mode 100644
index 00000000000..744d5b843aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10060.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 3.5508766527768394, "BUPRENORPHINE": 2.7410714448794997, "COMIRNATY": 0.1952246940451207, "CYTARABINE": 3.5795845893407408, "FENTANYL": 10.95348581911285, "GARDASIL": 0.8674763081436531, "GLUCAGON": 88.60645199749415, "IBUPROFEN": 1.930072246092705, "KALETRA": 3.3576071084727213, "MIDAZOLAM": 11.997571134563415, "MIRCERA": 44.575794100875946, "OLANZAPINE": 5.014290362477306, "SPIKEVAX": 0.2982357873261543, "TOZINAMERAN": 0.1817173791256618, "VAXZEVRIA": 0.0558134359802707, "null": 3.2253566730283683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10061.json
new file mode 100644
index 00000000000..d92e8cef423
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10061.json
@@ -0,0 +1 @@
+{"null": 1.655389132201088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10062.json
new file mode 100644
index 00000000000..ab7fc4e66f1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10062.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.648753427249641, "VAXZEVRIA": 1.056561100174203, "null": 0.6156577272746339}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10063.json
new file mode 100644
index 00000000000..3b13ea1d963
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10063.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.730860511511366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10064.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10064.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10065.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10065.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10066.json
new file mode 100644
index 00000000000..17a9c003f32
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10066.json
@@ -0,0 +1 @@
+{"BORTEZOMIB": 36.52636557711005, "BRIDION": 52.308664320776586, "BUPIVACAINE": 13.449411807082342, "CARFILZOMIB": 12.876809938230435, "COMIRNATY": 0.1067568385097867, "DEXAMETHASONE": 2.4693297994600703, "FENTANYL": 16.11195103358149, "FESOTERODINE": 1101.004184712733, "GLUCAGON": 64.35217573762536, "IBUPROFEN": 5.761632120987281, "MIDAZOLAM": 15.489969248305824, "OFEV": 14.659397352398202, "OPSUMIT": 4.880473474470437, "REMDESIVIR": 51.171587333413214, "SPIKEVAX": 0.3186010627922544, "TRACLEER": 3.031727869409328, "VAXZEVRIA": 0.0710063956134438, "null": 1.9115547939602773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10067.json
new file mode 100644
index 00000000000..6eb0de9fda2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10067.json
@@ -0,0 +1 @@
+{"NEVANAC": 158.59345767120948, "ZOSTAVAX": 24.863961726118525, "null": 2.2620312213427742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10068.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10068.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10069.json
new file mode 100644
index 00000000000..3ccbae04967
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10069.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8827709579365846, "VAXZEVRIA": 5.684479689874633}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1007.json
index 140ff9a798c..e83cb84fb1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1007.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1007.json
@@ -1 +1 @@
-{"ABILIFY": 1.525446083287243, "AFINITOR": 1.470454638808447, "ALIMTA": 1.547419285551456, "AMBROXOL": 312.51976967612313, "AMINOSALICYLIC": 15.655533377231198, "AMLODIPINE": 264.26574021931714, "BEDAQUILINE": 15.0832713668674, "CABOMETYX": 3.887987592434971, "CAFFEINE": 189.47457383055595, "CAPRELSA": 16.183524073014254, "CEFUROXIME": 75.65609615152682, "CYTARABINE": 1.599156442331806, "DELAMANID": 28.8577423156231, "ENTRESTO": 1.0513238116697377, "EVENITY": 13.234423592449104, "EXJADE": 6.663526877428926, "FENTANYL": 1.3492953147959046, "FORSTEO": 2.4195198182046336, "IBRANCE": 3.067188052037176, "KYMRIAH": 5.421222115419543, "LEMTRADA": 1.9546783069348332, "LEVOFLOXACIN": 88.41403438728841, "MEKINIST": 1.2256497086938298, "MIDAZOLAM": 2.305060839480027, "MIMPARA": 39.458404272688206, "NATPAR": 160.57237064988138, "OPSUMIT": 1.2295596794231127, "OZEMPIC": 19.014919689314556, "SOLIRIS": 3.1813955358978463, "SUTENT": 1.94812466283146, "VENETOCLAX": 5.576604509235185, "XTANDI": 1.247426626602811, "null": 1.1535741115965368}
\ No newline at end of file
+{"ABACAVIR": 0.738873421074763, "ACTRAPID": 16.767488677491823, "ANORO": 134.87173287386997, "APIXABAN": 20.58191002661052, "ARAVA": 0.1300253286692164, "ARIPIPRAZOLE": 5.498023834693302, "AVANDAMET": 51.45619721533965, "AVANDIA": 40.77317616096587, "AZATHIOPRINE": 7.775479516190434, "BUMETANIDE": 45.42836115240488, "BUPRENORPHINE": 3.371046948802795, "BYETTA": 7.340670388812847, "CHAMPIX": 0.7088897646305036, "CLOPIDOGREL": 2.1193245847616207, "COMBIVIR": 3.210630654223092, "COMIRNATY": 0.120830070487564, "DULOXETINE": 6.047192765712661, "ELIQUIS": 0.5584714960806306, "ENTRESTO": 1.7984539858592068, "ESBRIET": 4.783489840720489, "ICLUSIG": 4.056785561356703, "IRBESARTAN": 3.5859000766069, "JANUMET": 6.835829532451952, "JANUVIA": 7.126013386007306, "KEYTRUDA": 0.8895377957538447, "OLANZAPINE": 2.298743249804787, "PEGASYS": 0.9984081480419176, "PLAVIX": 1.3135930887480691, "PREGABALIN": 3.750352120746581, "SPIKEVAX": 0.1592087756281605, "TASIGNA": 6.378952193153356, "TOZINAMERAN": 0.0868341153465645, "VAXZEVRIA": 0.082509757386221, "ZOSTAVAX": 7.703473999972534, "ZYPREXA": 1.28159340881802, "null": 0.8792040903950542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10070.json
new file mode 100644
index 00000000000..558aed6150f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10070.json
@@ -0,0 +1 @@
+{"BETAFERON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10071.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10071.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10072.json
new file mode 100644
index 00000000000..3bfa6d1c075
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10072.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.3513473106733978, "SPIKEVAX": 2.9844699880524823, "null": 0.3763141476721929}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10073.json
new file mode 100644
index 00000000000..d46eb37b7b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10073.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.742314225298307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10074.json
new file mode 100644
index 00000000000..e546b1b10dd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10074.json
@@ -0,0 +1 @@
+{"ANGIOX": 603.795835892118, "CLOPIDOGREL": 17.0136229974328, "ELIQUIS": 6.519466087568056, "PLAVIX": 10.86325334049841, "null": 1.472590842057554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10075.json
new file mode 100644
index 00000000000..f9a1949fbb9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10075.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.912350940055606, "SPIKEVAX": 1.247886227983103, "null": 0.5255354764252819}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10076.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10076.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10077.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10077.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10078.json
new file mode 100644
index 00000000000..6be027aa19c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10078.json
@@ -0,0 +1 @@
+{"COMIRNATY": 6.81818455681856, "SPIKEVAX": 2.202286113585584, "VAXZEVRIA": 1.0664638708011076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10079.json
new file mode 100644
index 00000000000..f230e6382bd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10079.json
@@ -0,0 +1 @@
+{"COMIRNATY": 9.116959604817644, "SPIKEVAX": 2.123557960909207, "VAXZEVRIA": 1.637061544622438, "null": 0.1029393947084849}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1008.json
index 5168b2d3550..b0ff16d5e21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1008.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1008.json
@@ -1 +1 @@
-{"ACLIDINIUM": 9.75717599082466, "AFINITOR": 2.3403314432368343, "ARANESP": 9.826084718517018, "BONVIVA": 5.643798392857228, "BUDESONIDE": 20.55414381138715, "BYETTA": 1.813403089470724, "CARFILZOMIB": 13.519652356514186, "DENOSUMAB": 21.03030882339737, "EVENITY": 8.554528081514452, "EVISTA": 5.674320322379011, "FASLODEX": 1.554688906526179, "FORSTEO": 45.7803592108281, "IBRANCE": 2.0534482496794126, "INLYTA": 3.3685091442003534, "LEVOFLOXACIN": 2.6597231874285816, "MEKINIST": 2.577697898592423, "MIMPARA": 74.11910324376421, "NUCALA": 3.115085452267677, "PREOTACT": 121.49477305195362, "SUTENT": 2.3029227123000924, "TIVICAY": 10.782368581468528, "XTANDI": 1.075277231438423, "null": 1.6916001503677212}
\ No newline at end of file
+{"null": 0.6044606722756386}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10080.json
new file mode 100644
index 00000000000..2736c7f636e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10080.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.068857063625577, "SPIKEVAX": 2.7029194172027804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10081.json
new file mode 100644
index 00000000000..7891d5b06f2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10081.json
@@ -0,0 +1 @@
+{"KEPPRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10082.json
new file mode 100644
index 00000000000..b9bfaf7b78b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10082.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.918566212770695, "SPIKEVAX": 4.2626844448210806, "VAXZEVRIA": 0.8771535135428984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10083.json
new file mode 100644
index 00000000000..76669627fea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10083.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.086344314666861, "SPIKEVAX": 2.3260495576509728, "null": 0.3476500171942541}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10084.json
new file mode 100644
index 00000000000..40991961779
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10084.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10085.json
new file mode 100644
index 00000000000..61473373b45
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10085.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1290594428793303, "FENTANYL": 11.73105339968992, "GARDASIL": 1.7703965323268829, "GLUCAGON": 82.10159750584485, "NALOXONE": 95.07926110935236, "OLANZAPINE": 3.6035198468433984, "SPIKEVAX": 0.1718284413310319, "VAXZEVRIA": 0.1992092359671467, "null": 3.058620235068862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10086.json
new file mode 100644
index 00000000000..0722d6147ee
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10086.json
@@ -0,0 +1 @@
+{"null": 5.190975369480786}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10087.json
new file mode 100644
index 00000000000..4e0d5c2b3f9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10087.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2498764494953693, "null": 1.9330921244749968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10088.json
new file mode 100644
index 00000000000..f59c453dd0b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10088.json
@@ -0,0 +1 @@
+{"BUDESONIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10089.json
new file mode 100644
index 00000000000..cd25105d447
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10089.json
@@ -0,0 +1 @@
+{"null": 3.008591304009134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1009.json
index 129b5314f04..87438e2a572 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1009.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1009.json
@@ -1 +1 @@
-{"SPIKEVAX": 19.006821888465364}
\ No newline at end of file
+{"AIMOVIG": 5.793285441238239, "AVANDIA": 1.5725447802966062, "BRIDION": 41.87458609189188, "BUPIVACAINE": 7.462088978442651, "CAPECITABINE": 12.150336396887974, "CICLOSPORIN": 0.9593786933423948, "COMIRNATY": 0.0794060418677037, "ENBREL": 2.427378200962125, "FENTANYL": 6.207012823058885, "MIDAZOLAM": 6.970379619846817, "SPIKEVAX": 0.0783963688379957, "TASIGNA": 3.099328238618958, "TOZINAMERAN": 0.2381317771534822, "VAXZEVRIA": 0.0484083621040796, "null": 4.161089980614428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10090.json
new file mode 100644
index 00000000000..3276a3639b2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10090.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 1.9964047992136311, "COMIRNATY": 0.126103528184423, "FENTANYL": 3.051473379297884, "JETREA": 415.64417923908906, "MIDAZOLAM": 17.40187898653534, "VAXZEVRIA": 0.0705716962204052, "null": 3.7607656619179872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10091.json
new file mode 100644
index 00000000000..44d622cef96
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10091.json
@@ -0,0 +1 @@
+{"null": 3.7777276889172513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10092.json
new file mode 100644
index 00000000000..b7a2ebdac24
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10092.json
@@ -0,0 +1 @@
+{"null": 1.913393433494604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10093.json
new file mode 100644
index 00000000000..4658b69fcba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10093.json
@@ -0,0 +1 @@
+{"null": 9.065714050550593}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10094.json
new file mode 100644
index 00000000000..07bc649a54d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10094.json
@@ -0,0 +1 @@
+{"ADEMPAS": 2.712762989969136, "ALIMTA": 2.9734339382927057, "ANAKINRA": 1.1954927688658223, "APIDRA": 0.5651832437995029, "ARAVA": 0.1208575439563841, "ATRIPLA": 0.0712007227632839, "AVASTIN": 0.7252284632124931, "BETMIGA": 2.520140639626995, "BRILIQUE": 3.610607202377466, "CANCIDAS": 3.0718095777952747, "CHAMPIX": 0.3562476412824021, "CICLOSPORIN": 0.7938220926599978, "CIMZIA": 0.2270333635495107, "CIRCADIN": 10.53706242415973, "CLOPIDOGREL": 3.764648514036423, "COMIRNATY": 0.4596352431092027, "COTELLIC": 7.653219576577805, "CUBICIN": 2.030812692706112, "CYMBALTA": 0.3493711013111158, "DEXAMETHASONE": 0.674901453192385, "ELIQUIS": 2.157444559748862, "ENOXAPARIN": 4.226771395374707, "ENTRESTO": 0.4454503987624805, "EXJADE": 0.5952104105510645, "FASENRA": 0.8515849514801187, "GARDASIL": 0.4617217333020807, "IBUPROFEN": 0.6119521759399515, "INCIVO": 1.1249417926014644, "IRESSA": 2.414375016645368, "JAKAVI": 0.6744355506754424, "JANUVIA": 0.8111483110106833, "JARDIANCE": 0.3941346060603948, "KEPPRA": 0.4744657102612485, "KEYTRUDA": 0.610849803103629, "LANTUS": 0.2816495880546139, "LEMTRADA": 1.0080768354834502, "LEVETIRACETAM": 0.9432870420571594, "LEVOFLOXACIN": 1.859344024551156, "LIXIANA": 3.008567848157621, "METHOTREXATE": 0.5043575324506004, "MICARDIS": 0.8934490659591913, "MIMPARA": 3.4626281311087963, "MMRVAXPRO": 0.7667228416127386, "NEXAVAR": 1.345244396559795, "NOVONORM": 4.640106985486704, "NPLATE": 4.146955793793382, "NUCALA": 0.5272842695206654, "PEGASYS": 1.0703372448336672, "PEGINTERFERON": 1.0783618243471158, "PEGINTRON": 1.0587707795861023, "PLAVIX": 4.3207026578143655, "PREVENAR": 6.652964799963264, "ROACTEMRA": 1.083035915448773, "SHINGRIX": 0.3129405178407122, "SPIKEVAX": 0.2477550534287982, "STELARA": 0.2477520386647674, "STIVARGA": 0.543133069470954, "SUTENT": 0.948079393347976, "TAGRISSO": 1.3290459366813194, "TAMIFLU": 1.0059141063049428, "TEMODAL": 4.5105509531288135, "TICAGRELOR": 2.5606403193661684, "TOZINAMERAN": 0.4384813868104376, "VAXZEVRIA": 0.5578831182124269, "VOTRIENT": 0.4284108357209365, "XARELTO": 3.444562522533756, "XOLAIR": 0.7158908389221373, "ZOSTAVAX": 0.3457777289751799, "ZYPREXA": 0.2654081626019792, "null": 2.433556713770333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10095.json
new file mode 100644
index 00000000000..c01f068e336
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10095.json
@@ -0,0 +1 @@
+{"null": 1.185351215009184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10096.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10096.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10097.json
new file mode 100644
index 00000000000..4ce6dc1818f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10097.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6297370698202258, "null": 1.795369400727517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10098.json
new file mode 100644
index 00000000000..927542d2f87
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10098.json
@@ -0,0 +1 @@
+{"CELECOXIB": 986.279486566102, "DEXAMETHASONE": 22.53477599001124, "null": 0.613338291998829}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10099.json
new file mode 100644
index 00000000000..2555ddddcde
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10099.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 4.024197317040237, "COMIRNATY": 0.3935599443448904, "SUTENT": 2.7821604541876006, "null": 1.467486975909712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/101.json
index 51f3918f30c..2d25fea8fb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/101.json
@@ -1 +1 @@
-{"APIXABAN": 325.4498570287546, "BUDESONIDE": 117.87009940609104}
\ No newline at end of file
+{"null": 2.212712716221833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1010.json
index 199e79048bc..1c7308a8d0f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1010.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1010.json
@@ -1 +1 @@
-{"null": 2.3523687945817944}
\ No newline at end of file
+{"COMIRNATY": 0.3140210902483517, "null": 0.9174639563767572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10100.json
new file mode 100644
index 00000000000..0d1e55286ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10100.json
@@ -0,0 +1 @@
+{"AMINOSALICYLIC": 17.430934757856942, "ARAVA": 0.587943417181428, "CICLOSPORIN": 7.7165435993478, "COMIRNATY": 0.1359795069866322, "FENTANYL": 3.076882998450793, "HUMIRA": 4.03396463675811, "IBUPROFEN": 10.317530946977111, "IRON": 32.42946803969209, "LEVOFLOXACIN": 3.2039377315656603, "RINVOQ": 6.189888923183759, "null": 1.3316570783487238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10101.json
new file mode 100644
index 00000000000..63a755acd72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10101.json
@@ -0,0 +1 @@
+{"RITUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10102.json
new file mode 100644
index 00000000000..d99553a519f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10102.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 2.514800850119804, "ARAVA": 2.681353727273892, "AUBAGIO": 2.4652773125089773, "CICLOSPORIN": 7.246508017429618, "CIMZIA": 6.989717702918098, "COMIRNATY": 0.2300908509552116, "COSENTYX": 23.164050341267984, "ENBREL": 2.031763340781198, "HUMIRA": 4.93071027387284, "NEXAVAR": 2.572310224818957, "SIMPONI": 17.7407088716539, "SPIKEVAX": 0.0834970549007641, "STELARA": 34.08286598345405, "TOZINAMERAN": 0.3218126723053763, "TREMFYA": 30.30379757164036, "VAXZEVRIA": 0.0811586785816893, "null": 0.8664396784815727}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10103.json
new file mode 100644
index 00000000000..c1618199d75
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10103.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.1065839101178898, "ARANESP": 0.9393122896420536, "ARAVA": 0.2220349335794695, "AUBAGIO": 0.8564006128528409, "CICLOSPORIN": 2.548352128960863, "CIMZIA": 0.8621773574834638, "COMIRNATY": 0.5809834337370229, "COSENTYX": 6.537763833755762, "DEXAMETHASONE": 0.96418960046044, "ELIQUIS": 0.8585062663725698, "ENBREL": 0.9609803746171895, "ENTRESTO": 1.9891586407800328, "ENTYVIO": 1.4090825799429956, "FASENRA": 2.391768157154317, "INCIVO": 3.872909193914136, "JARDIANCE": 2.0364804151905327, "KEYTRUDA": 0.5062512795820907, "LANTUS": 0.5398644875241595, "LEVOFLOXACIN": 1.921558814821428, "MMRVAXPRO": 0.8533736294655244, "NEXAVAR": 2.446503208664056, "OMALIZUMAB": 1.4430298619061366, "PEGASYS": 0.3902489712304047, "RINVOQ": 8.319022454219752, "ROACTEMRA": 4.75500304798542, "SHINGRIX": 6.67860217576878, "SIMPONI": 1.6456015121844187, "SPIKEVAX": 0.501858604477436, "STELARA": 2.0523916506131923, "STIVARGA": 1.8570119058244527, "TAGRISSO": 2.946345586943139, "TOZINAMERAN": 0.3240514852222818, "TREMFYA": 2.6556441451594037, "VAXZEVRIA": 0.2237725761336872, "XELJANZ": 0.5954735196028647, "XOLAIR": 0.8741711714048845, "null": 1.7831420060042005}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10104.json
new file mode 100644
index 00000000000..9b7b3acf93e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10104.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 10.7139145146855, "COMIRNATY": 0.5249087613500744, "ELIQUIS": 40.68768422843074, "PLAVIX": 9.197430563161886, "null": 0.6276013819731098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10105.json
new file mode 100644
index 00000000000..9abac0083ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10105.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5089563597081296, "null": 0.487300345991527}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10106.json
new file mode 100644
index 00000000000..d70a39a7e04
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10106.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 62.71274736489988, "COMBIVIR": 24.966858157739416, "KALETRA": 27.602525332808696, "null": 1.185721404619997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10107.json
new file mode 100644
index 00000000000..9cf2cbedaea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10107.json
@@ -0,0 +1 @@
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10108.json
new file mode 100644
index 00000000000..b80ee3428cd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10108.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.072893906840536, "ADVAGRAF": 24.11309473041598, "AMIKACIN": 4.239618964789491, "ATRIPLA": 0.5621934926486939, "AUBAGIO": 0.8804480887041828, "BEDAQUILINE": 4.991611056082786, "BENLYSTA": 2.23970263059006, "BYETTA": 1.5768576698027958, "CELLCEPT": 9.586933559499982, "CICLOSPORIN": 2.10432192419197, "CIMZIA": 1.968905423197803, "COMBIVIR": 6.442216334082375, "COMIRNATY": 0.3875564101516895, "COSENTYX": 1.7629092144754228, "CRIXIVAN": 6.738935631121545, "CYMBALTA": 0.3741274892848717, "ELIQUIS": 0.3024262581540672, "EMPAGLIFLOZIN": 8.135602444809566, "ENBREL": 2.116918341867629, "EXJADE": 1.2245880094364152, "FORSTEO": 1.324612004284015, "FORXIGA": 33.60963417318678, "GARDASIL": 1.5299670197875526, "HUMALOG": 1.92047683631337, "HUMIRA": 1.465310826833315, "IBRANCE": 0.4838331922380294, "INVOKANA": 20.150744044135763, "JAKAVI": 1.7198413808408124, "JANUMET": 1.045781038195389, "JANUVIA": 1.064671768038865, "JARDIANCE": 24.79983701896609, "KEYTRUDA": 2.8259934171817886, "LYRICA": 1.2172493751831348, "MEPOLIZUMAB": 1.4975195147896814, "METHOTREXATE": 2.090334608606345, "MYCOPHENOLATE": 3.543776549256607, "NEXAVAR": 0.5942466490716722, "OMALIZUMAB": 2.136356078653054, "PEGASYS": 1.5566995170713942, "PEGINTRON": 2.421579526196039, "REMICADE": 4.266567860485032, "ROACTEMRA": 3.8594621780833593, "SIMPONI": 4.7746033542922905, "SOLIRIS": 2.1867712711530545, "SPIKEVAX": 0.1262347410397114, "STELARA": 1.647918448648, "STIVARGA": 1.237502705675029, "SUTENT": 0.2868594961568694, "TELMISARTAN": 6.255679723179492, "TOVIAZ": 2.459373624519442, "TRUVADA": 0.3670931631839468, "VAXZEVRIA": 0.1035198376468546, "XELJANZ": 1.6178888551415676, "XOLAIR": 0.8987384730402704, "ZOSTAVAX": 0.6357384635996315, "ZYPREXA": 0.5340481486926707, "null": 0.6267437072108772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10109.json
new file mode 100644
index 00000000000..45d45a36981
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10109.json
@@ -0,0 +1 @@
+{"CELECOXIB": 42.67883411725485, "CELLCEPT": 9.86140304445184, "COMIRNATY": 0.2994862335930289, "FORXIGA": 54.7364002623841, "JARDIANCE": 17.500154265704257, "PEGASYS": 1.6520557508716636, "SIMPONI": 2.824849547637675, "XELJANZ": 2.0291378587991566, "null": 0.6508236657294806}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1011.json
index 6b023145317..295b71cea97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1011.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1011.json
@@ -1 +1 @@
-{"null": 1.009551223095855}
\ No newline at end of file
+{"VELTASSA": 291.3353824941928, "null": 0.5049055256884603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10110.json
new file mode 100644
index 00000000000..c48b0d2973f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10110.json
@@ -0,0 +1 @@
+{"BEDAQUILINE": 101.42117345549948, "FORXIGA": 45.58790470114312, "null": 0.6085433431850994}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10111.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10111.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10112.json
new file mode 100644
index 00000000000..c1bbb4b698c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10112.json
@@ -0,0 +1 @@
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10113.json
new file mode 100644
index 00000000000..9875c031653
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10113.json
@@ -0,0 +1 @@
+{"null": 3.844384524859244}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10114.json
new file mode 100644
index 00000000000..a3bfc9f841c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10114.json
@@ -0,0 +1 @@
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10115.json
new file mode 100644
index 00000000000..2d96df81101
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10115.json
@@ -0,0 +1 @@
+{"CELLCEPT": 19.305992922623037, "null": 0.5982711438637125}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10116.json
new file mode 100644
index 00000000000..32894cc29ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10116.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 2.840154798548823, "ARAVA": 0.499323705482037, "CICLOSPORIN": 12.161400148153012, "CIMZIA": 1.930794455461032, "COMIRNATY": 0.1956792293397838, "COSENTYX": 5.889162061940557, "ENTYVIO": 34.64187758209252, "HUMIRA": 6.123685467308383, "JAKAVI": 6.270867534750741, "ROACTEMRA": 11.484992139874665, "SIMPONI": 6.1649861325745885, "STELARA": 13.10155046679694, "SUTENT": 5.948685801636843, "VOTRIENT": 4.510479234840365, "null": 0.4318614520354965}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10117.json
new file mode 100644
index 00000000000..48575307729
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10117.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 34.13502684743326, "null": 1.2501220717670978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10118.json
new file mode 100644
index 00000000000..c8eaa7dd093
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10118.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 56.19290957740202, "CYTARABINE": 44.54872015749093, "null": 0.5868878430062934}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10119.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10119.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1012.json
index d178859d8ce..e26ca121dd2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1012.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1012.json
@@ -1 +1 @@
-{"BEDAQUILINE": 41.89213916216588, "CELECOXIB": 35.98760026635491, "DELAMANID": 42.32635729167484, "EMEND": 33.369018037201094, "ENTRESTO": 4.229118504721679, "EXJADE": 6.042427153229768, "MICARDIS": 11.733266164072802, "OLANZAPINE": 3.002825638621942, "ZYPREXA": 2.3126415676723826, "null": 1.93237772527366}
\ No newline at end of file
+{"null": 0.882049050778564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10120.json
new file mode 100644
index 00000000000..2762ddf0fc6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10120.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2968911513736388, "null": 1.9739382080054144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10121.json
new file mode 100644
index 00000000000..3ef9f8e0f35
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10121.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.0636605429430603, "ABASAGLAR": 0.0439222244924425, "ABATACEPT": 0.2680763928332544, "ABILIFY": 0.0768332666404051, "ABRAXANE": 0.4324275675414341, "ACCOFIL": 1.2456900731190157, "ACLASTA": 0.4655088417948456, "ACLIDINIUM": 0.1357172539602003, "ACTOS": 0.3201529961033741, "ACTRAPID": 0.152409355262741, "ADALIMUMAB": 0.205646601958316, "ADCETRIS": 0.539740788777937, "ADCIRCA": 0.1903228230918266, "ADEMPAS": 0.1104721334886585, "ADENURIC": 0.314966211171451, "ADVAGRAF": 0.1779950063901711, "ADVATE": 0.1747263571977239, "AERIUS": 0.19164333557503, "AFINITOR": 0.5366845229817427, "AFLIBERCEPT": 0.2216046418773031, "AIMOVIG": 0.0984693982573179, "ALDARA": 0.8995224450934856, "ALEMTUZUMAB": 0.6904018593532956, "ALIGN": 1.1328849981359437, "ALIMTA": 0.5319021522307973, "ALL": 0.1132825246082468, "ALOXI": 0.223981618853567, "ALPELISIB": 0.3511636176384886, "AMBIRIX": 1.817212528509832, "AMBRISENTAN": 0.1730389200284428, "AMGEVITA": 0.5271365257412596, "AMIKACIN": 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0.8897990965700645, "VIRAMUNE": 1.8664251090916404, "VIREAD": 0.062027115329755, "VORICONAZOLE": 0.3622427911883846, "VOTRIENT": 0.1723156739498726, "VYXEOS": 1.2152847341141613, "XALKORI": 0.2913806186437711, "XARELTO": 0.0900377945690116, "XELJANZ": 0.2464960067127679, "XELODA": 0.3048916828893953, "XOFIGO": 0.2167226294623432, "XOLAIR": 0.3553931902601593, "XTANDI": 0.1052518934059104, "YERVOY": 0.4061638991072032, "YESCARTA": 1.283122945857286, "YONDELIS": 0.2850591997338894, "ZALTRAP": 0.5099504826759201, "ZARZIO": 0.8449911299885939, "ZAVESCA": 0.3260420741212856, "ZEJULA": 0.1427593842267326, "ZELBORAF": 0.7233122603839143, "ZEPATIER": 0.1263115663676277, "ZIAGEN": 2.4477482129329, "ZINBRYTA": 0.1862961521465976, "ZOLEDRONIC": 0.4751434295677869, "ZOMETA": 0.3673308794640532, "ZONISAMIDE": 0.3325258448573913, "ZOSTAVAX": 0.1636407404601812, "ZYCLARA": 0.6210107524622692, "ZYPADHERA": 0.1443428363817943, "ZYPREXA": 0.2779702855594463, "null": 0.3331986791748449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10122.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10122.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10123.json
new file mode 100644
index 00000000000..bb6b15e329b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10123.json
@@ -0,0 +1 @@
+{"null": 2.730503190934328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10124.json
new file mode 100644
index 00000000000..d26f11b4236
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10124.json
@@ -0,0 +1 @@
+{"null": 5.085740202851119}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10125.json
new file mode 100644
index 00000000000..90eef23deff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10125.json
@@ -0,0 +1 @@
+{"ENOXAPARIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10126.json
new file mode 100644
index 00000000000..6f8d2407763
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10126.json
@@ -0,0 +1 @@
+{"CELECOXIB": 29.260658892586427, "CELLCEPT": 9.141311021764157, "COMIRNATY": 0.099809125084543, "FORXIGA": 10.644355551112712, "null": 1.3202207312941834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10127.json
new file mode 100644
index 00000000000..75f5adb7d81
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10127.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4436086879719903, "SPIKEVAX": 0.4857438454946572, "TOZINAMERAN": 1.3312807097406103, "VAXZEVRIA": 7.397398860313045, "null": 0.1096378587062549}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10128.json
new file mode 100644
index 00000000000..ac4ae485134
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10128.json
@@ -0,0 +1 @@
+{"null": 2.27387390745382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10129.json
new file mode 100644
index 00000000000..b031d66d21b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10129.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8211459394097795, "null": 0.966937321188353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1013.json
index fc8ace0ee5c..8bed1b2bf75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1013.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1013.json
@@ -1 +1 @@
-{"BEDAQUILINE": 16.422352830707872, "CARBIDOPA": 66.95389642497081, "ENTRESTO": 16.278540927303148, "EXJADE": 13.48837494653984, "KYMRIAH": 10.89032492788458, "LACOSAMIDE": 59.27522587770058, "LEVETIRACETAM": 104.64334134233098, "OLANZAPINE": 3.0919741061681267}
\ No newline at end of file
+{"null": 1.3534383220088049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10130.json
new file mode 100644
index 00000000000..509fec4ee8f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10130.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 4.792505042597516, "BUPRENORPHINE": 9.833412644520626, "CLOPIDOGREL": 4.069683823479804, "COMIRNATY": 0.8655014756196975, "CYTARABINE": 4.3491671698186, "FENTANYL": 6.943831080255423, "GARDASIL": 1.7010309434695736, "KEPPRA": 2.1763510756146363, "OLANZAPINE": 3.937358061498183, "SPIKEVAX": 0.2328318156394445, "TWINRIX": 16.515962612042877, "VAXZEVRIA": 0.5701770261779406, "null": 1.0628513183686044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10131.json
new file mode 100644
index 00000000000..7310edcd277
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10131.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 2.4020829520188363, "CLOPIDOGREL": 3.245209106698548, "COMIRNATY": 0.447062732566207, "DEXAMETHASONE": 4.809409898683318, "DOXORUBICIN": 18.82003183202208, "LEMTRADA": 7.707385639263836, "MIDAZOLAM": 12.418059419626864, "NAGLAZYME": 23.55633315203572, "PLAVIX": 1.8412970572769052, "SPIKEVAX": 0.1133996400691908, "VAXZEVRIA": 0.2529820486111587, "null": 2.0622360741909893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10132.json
new file mode 100644
index 00000000000..daa23757385
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10132.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.7243728782548453, "ADALIMUMAB": 0.3692566405992414, "AIMOVIG": 2.3882073898692138, "ANAKINRA": 9.720849353731792, "ARAVA": 0.2192566197479651, "ATRIPLA": 13.159943557925674, "AVANDIA": 0.5325146806730886, "AZATHIOPRINE": 2.807306579869609, "BUPRENORPHINE": 0.8847448405920759, "CELECOXIB": 3.693080239636271, "CICLOSPORIN": 1.5559432517596097, "CIMZIA": 2.4713719824224247, "COMIRNATY": 0.4331142707545324, "COSENTYX": 0.4446242361842808, "CYMBALTA": 0.2658905951776599, "ELIQUIS": 0.2691250109310086, "ENTACAPONE": 10.613974978487114, "ENTRESTO": 0.7215380399224646, "FENTANYL": 1.1794268693050711, "GARDASIL": 1.4089989880731169, "HYDROCORTISONE": 2.325508704833434, "KEYTRUDA": 0.6654124058029974, "LANTUS": 0.3065263414338234, "LYRICA": 1.0832164723178193, "MEPOLIZUMAB": 1.7144764213872723, "METHOTREXATE": 1.3751235772137886, "NUCALA": 7.689225857265576, "OMALIZUMAB": 2.652828409914864, "OPSUMIT": 0.6299308681122292, "OPTIMARK": 10.337816255591784, "SOLIRIS": 1.1557362357345882, "SPIKEVAX": 0.1920741652772033, "STRIBILD": 8.731561370371342, "SUBOXONE": 0.6544055736010451, "SUTENT": 0.874202450962457, "TOZINAMERAN": 0.3673945583130777, "TRUVADA": 7.574126414369448, "VAXZEVRIA": 0.0770137321580129, "VIREAD": 8.559122373653844, "VOTRIENT": 1.4162512075308988, "XELJANZ": 0.3999219171812125, "XOLAIR": 1.2236200745323924, "XTANDI": 1.6001516691830076, "ZOSTAVAX": 2.0273077566428004, "ZYPREXA": 0.4247436679655537, "null": 0.898977585202013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10133.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10133.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10134.json
new file mode 100644
index 00000000000..989719190c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10134.json
@@ -0,0 +1 @@
+{"BENLYSTA": 49.69031446954102, "NUCALA": 86.03756735730167, "null": 0.3326831664830164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10135.json
new file mode 100644
index 00000000000..0f20649561a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10135.json
@@ -0,0 +1 @@
+{"PACLITAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10136.json
new file mode 100644
index 00000000000..bac674c2fa1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10136.json
@@ -0,0 +1 @@
+{"null": 1.2435810430680123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10137.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10137.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10138.json
new file mode 100644
index 00000000000..ca6844595bc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10138.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.2989062203694044, "MIRABEGRON": 1483.774764809838, "null": 0.7764183008908029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10139.json
new file mode 100644
index 00000000000..cd12dfb602b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10139.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.0786507081855037, "SPIKEVAX": 0.8030970324014318, "null": 0.8169529309548748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1014.json
index 7d2f66dcd68..5a85e49b959 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1014.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1014.json
@@ -1 +1 @@
-{"SPIKEVAX": 36.95909529489059}
\ No newline at end of file
+{"ARANESP": 31.45558775969433, "null": 0.8498952565577536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10140.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10140.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10141.json
new file mode 100644
index 00000000000..5d311e4bb17
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10141.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.3926350039239344, "null": 1.7513232568098986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10142.json
new file mode 100644
index 00000000000..cd6a488d6b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10142.json
@@ -0,0 +1 @@
+{"null": 1.0160645214141928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10143.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10143.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10144.json
new file mode 100644
index 00000000000..ed0aca61250
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10144.json
@@ -0,0 +1 @@
+{"OPDIVO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10145.json
new file mode 100644
index 00000000000..ef80608db89
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10145.json
@@ -0,0 +1 @@
+{"METHOTREXATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10146.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10146.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10147.json
new file mode 100644
index 00000000000..4f26f607923
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10147.json
@@ -0,0 +1 @@
+{"IBRANCE": 19.61400538964656, "KEYTRUDA": 6.785229501095956, "null": 0.7683205756822835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10148.json
new file mode 100644
index 00000000000..47c7bf06b18
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10148.json
@@ -0,0 +1 @@
+{"HUMALOG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10149.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10149.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1015.json
index 69215890275..68871f067c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1015.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1015.json
@@ -1 +1 @@
-{"ABATACEPT": 12.165598739048407, "ADALIMUMAB": 13.545587801759297, "BELIMUMAB": 502.00280067980657, "CLOPIDOGREL": 35.45634961220281}
\ No newline at end of file
+{"OPTIMARK": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10150.json
new file mode 100644
index 00000000000..47c7bf06b18
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10150.json
@@ -0,0 +1 @@
+{"HUMALOG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10151.json
new file mode 100644
index 00000000000..d8ff5fb4e76
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10151.json
@@ -0,0 +1 @@
+{"null": 0.607446179040787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10152.json
new file mode 100644
index 00000000000..85b74d8d7c5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10152.json
@@ -0,0 +1 @@
+{"IPILIMUMAB": 112.07697226903947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10153.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10153.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10154.json
new file mode 100644
index 00000000000..ed0aca61250
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10154.json
@@ -0,0 +1 @@
+{"OPDIVO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10155.json
new file mode 100644
index 00000000000..ff225af61de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10155.json
@@ -0,0 +1 @@
+{"null": 0.3643902650883761}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10156.json
new file mode 100644
index 00000000000..67c09efec54
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10156.json
@@ -0,0 +1 @@
+{"FASLODEX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10157.json
new file mode 100644
index 00000000000..7807b460e1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10157.json
@@ -0,0 +1 @@
+{"ADEMPAS": 54.69337486707991, "ALIMTA": 26.29113537833904, "IMFINZI": 1927.4831366743665, "IRESSA": 56.526177196016455, "KEYTRUDA": 32.06996900287799, "OPDIVO": 32.73041213859531, "null": 0.2967937488911819}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10158.json
new file mode 100644
index 00000000000..314e55022cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10158.json
@@ -0,0 +1 @@
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10159.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10159.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1016.json
index bf1cbe054ca..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1016.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1016.json
@@ -1 +1 @@
-{"BELIMUMAB": 60.07266253242842, "BENLYSTA": 3.3069041875687133, "BYDUREON": 5.854940637230367, "CYMBALTA": 1.2374518891016402, "GLYCOPYRRONIUM": 34.820862400272105, "HUMALOG": 1.0143169302432642, "JANUMET": 7.850364523430417, "JANUVIA": 3.6104248793646816, "MICARDIS": 7.818801728442826, "SOMAVERT": 125.68558345530217, "SUTENT": 1.3587867871604802, "XELJANZ": 3.745905280483345, "ZOSTAVAX": 47.089015037076656, "ZYPREXA": 18.721964369663095, "null": 1.4444133062503577}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10160.json
new file mode 100644
index 00000000000..354c7b90694
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10160.json
@@ -0,0 +1 @@
+{"XTANDI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10161.json
new file mode 100644
index 00000000000..a716267088c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10161.json
@@ -0,0 +1 @@
+{"ISENTRESS": 87.4089110720285, "null": 0.761730982527073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10162.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10162.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10163.json
new file mode 100644
index 00000000000..20353746d6a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10163.json
@@ -0,0 +1 @@
+{"null": 2.6158037147864275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10164.json
new file mode 100644
index 00000000000..b4ff0d48e6c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10164.json
@@ -0,0 +1 @@
+{"null": 3.8035161185409874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10165.json
new file mode 100644
index 00000000000..f85f4bd7366
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10165.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4331918606204053, "SPINRAZA": 83.89137901624666, "null": 0.7435408029974562}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10166.json
new file mode 100644
index 00000000000..8a2cde9f400
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10166.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.8498616159167385, "SPIKEVAX": 0.935938370656052, "TOZINAMERAN": 4.140196979606087, "VAXZEVRIA": 1.729627526073015, "null": 0.1574363920595643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10167.json
new file mode 100644
index 00000000000..2eb1cc5178d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10167.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 16.814992095198797, "ALIGN": 226.210064349624, "AMINOSALICYLIC": 123.76427984701807, "ATRIPLA": 0.2912299708284009, "AVAMYS": 63.86569190091807, "BUDESONIDE": 91.9818607997044, "CICLOSPORIN": 0.4567138115413716, "COMIRNATY": 0.3399377967312811, "CYMBALTA": 0.3299731915969643, "GARDASIL": 0.8695497883132981, "HYDROCORTISONE": 8.930861243177445, "IPILIMUMAB": 2.3856552349305784, "KEYTRUDA": 0.5644075938343963, "PREGABALIN": 35.468713699487, "SHINGRIX": 1.1844091572202953, "SPIKEVAX": 0.1384663136120798, "SUFENTANIL": 5.971469817310013, "TOZINAMERAN": 0.1587474658741907, "TRUVADA": 0.3320977668692675, "TWINRIX": 4.7313983632975045, "VAXZEVRIA": 0.1651881808777663, "ZOSTAVAX": 2.1724806883659715, "null": 0.2104879122271146}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10168.json
new file mode 100644
index 00000000000..3a9d0cf08cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10168.json
@@ -0,0 +1 @@
+{"null": 2.118328606160788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10169.json
new file mode 100644
index 00000000000..14f8d5fa251
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10169.json
@@ -0,0 +1 @@
+{"AUBAGIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1017.json
index aed74939c7e..cd238ae8376 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1017.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1017.json
@@ -1 +1 @@
-{"DENOSUMAB": 127.25585428435734, "PLAVIX": 6.074325505852805, "null": 1.6132096345615383}
\ No newline at end of file
+{"BASILIXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10170.json
new file mode 100644
index 00000000000..b947388cdb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10170.json
@@ -0,0 +1 @@
+{"BYDUREON": 6.813425837090988, "BYETTA": 13.138150580608652, "JANUMET": 29.395175491097792, "JANUVIA": 30.19286576594793, "KEYTRUDA": 21.861577801103493, "NEULASTA": 34.391378622403955, "PEMBROLIZUMAB": 31.935016428110057, "TRACLEER": 5.300263592362989, "VOTRIENT": 22.116721311726277, "null": 0.963457838092671}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10171.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10171.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10172.json
new file mode 100644
index 00000000000..c0a5e9f5891
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10172.json
@@ -0,0 +1 @@
+{"JANUMET": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10173.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10173.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10174.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10174.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10175.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10175.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10176.json
new file mode 100644
index 00000000000..567ea79a01a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10176.json
@@ -0,0 +1 @@
+{"ATRIPLA": 21.679125616598764, "ENTRESTO": 4.409715182969413, "EVENITY": 101.206244799868, "EVISTA": 17.44173877223233, "FORSTEO": 5.2058989634648105, "NUCALA": 4.711926207484267, "STRIBILD": 5.277221955770337, "TRUVADA": 10.440973052944384, "null": 0.5565725927362872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10177.json
new file mode 100644
index 00000000000..a0ab6d3da04
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10177.json
@@ -0,0 +1 @@
+{"AFINITOR": 2.577428377861485, "APIXABAN": 1.8090938250464863, "ARAVA": 0.2138243767097516, "ATAZANAVIR": 4.205662357104036, "BENRALIZUMAB": 97.09260983396833, "BIKTARVY": 6.495677077113978, "BUDESONIDE": 9.169499734078244, "BUPIVACAINE": 9.965619968069872, "CELLCEPT": 3.077323551518436, "CICLOSPORIN": 3.087094945357062, "CLOPIDOGREL": 4.223166489829046, "COMIRNATY": 0.1816850071911543, "CUBICIN": 3.57432013906676, "ELIQUIS": 0.3278880492808001, "ENTRESTO": 5.769772770862655, "ESBRIET": 2.6405380964200096, "EXJADE": 2.675232185901105, "FENTANYL": 1.4987528630602798, "INSULIN": 19.27915013532489, "IRBESARTAN": 4.144111679596472, "IVABRADINE": 30.680095877063952, "LEVOFLOXACIN": 1.6752596239823216, "MEPOLIZUMAB": 21.555265529438767, "MICARDIS": 2.4995400933993293, "MYCOPHENOLATE": 3.842133121245576, "NUCALA": 2.927705215072991, "OMALIZUMAB": 1.4373927915818805, "OPSUMIT": 1.6903243430031758, "ORKAMBI": 6.697439608737049, "PEGINTERFERON": 2.1896283999018222, "RIVAROXABAN": 13.940389525255403, "SPIKEVAX": 0.1318783731119615, "SPIRONOLACTONE": 6.715525512405667, "SYNAGIS": 3.298053290958874, "TOZINAMERAN": 0.1617218058742985, "TRACLEER": 1.2682503893023371, "VAXZEVRIA": 0.037614554086458, "XOLAIR": 2.939297022574942, "null": 1.620750347602087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10178.json
new file mode 100644
index 00000000000..e100a72c0ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10178.json
@@ -0,0 +1 @@
+{"SAMSCA": 5993.302475013472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10179.json
new file mode 100644
index 00000000000..d7528228bca
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10179.json
@@ -0,0 +1 @@
+{"null": 2.880590035536887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1018.json
index 510a842453e..6ec01afe9b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1018.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1018.json
@@ -1 +1 @@
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\ No newline at end of file
+{"AVANDIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10180.json
new file mode 100644
index 00000000000..8d72122062e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10180.json
@@ -0,0 +1 @@
+{"null": 1.4484020503348496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10181.json
new file mode 100644
index 00000000000..e67b8184075
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10181.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10182.json
new file mode 100644
index 00000000000..b6485425a30
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10182.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10183.json
new file mode 100644
index 00000000000..55e1348afb4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10183.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5087615871331784, "null": 0.5916947803524273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10184.json
new file mode 100644
index 00000000000..bc5e78ff7e8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10184.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10185.json
new file mode 100644
index 00000000000..4c5c7ff769c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10185.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.2880194032678083, "ABASAGLAR": 1.702724383580082, "ABILIFY": 0.1520963884054693, "ADENURIC": 2.9871620941197548, "AERIUS": 3.788264273179748, "AFINITOR": 0.2412878998623516, "AIMOVIG": 0.0972192794153338, "ALEMTUZUMAB": 0.4601788494447033, "ALIMTA": 3.498597603812271, "ALPELISIB": 4.030981195593474, "AMIKACIN": 8.859653169574724, "APIXABAN": 0.1897102973890314, "APROVEL": 1.4293357521702628, "ARANESP": 1.208863967058763, "ARAVA": 0.2232601180426159, "ARIXTRA": 17.28816975892597, "ASPARAGINASE": 0.8386261483699788, "ATRIPLA": 0.0712441339544193, "AUBAGIO": 0.2615442541216705, "AZACITIDINE": 0.5938093043093153, "AZTREONAM": 3.864900755734383, "BEVACIZUMAB": 0.2950196268111273, "BEXSERO": 1.2264640966311484, "BIKTARVY": 1.2756407244478745, "BINOCRIT": 6.885778303271618, "BORTEZOMIB": 0.8956364337694138, "BRAFTOVI": 0.5933718886674914, "BRIDION": 1.705485441286868, "BRILIQUE": 4.689011455180608, "BRINTELLIX": 0.1936485862619752, "BUDESONIDE": 0.4196925166988255, "BUSILVEX": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10186.json
new file mode 100644
index 00000000000..89d602bf857
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10186.json
@@ -0,0 +1 @@
+{"null": 1.5265352755504136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10187.json
new file mode 100644
index 00000000000..c7c2e80cb72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10187.json
@@ -0,0 +1 @@
+{"AERIUS": 2.213243393714444, "AMIKACIN": 2.793935905518331, "BEXSERO": 4.887741439454701, "BUDESONIDE": 0.9443492136328586, "CANCIDAS": 6.611616611287412, "COMIRNATY": 0.1180561030498028, "COTELLIC": 3.659702749891444, "DEXAMETHASONE": 0.5154536074822732, "ELIQUIS": 0.264562190562078, "INFANRIX": 2.5648335564520037, "KEPPRA": 0.2966832229226359, "LEVETIRACETAM": 0.7374406698909902, "LEVOFLOXACIN": 0.8245361535925684, "LIXIANA": 2.5655028597435705, "LYRICA": 0.6393685178182825, "MMRVAXPRO": 223.28548270895348, "NEXAVAR": 0.4302022552562303, "NIMENRIX": 3.5595553197714955, "PANTOPRAZOLE": 1.0277981482842309, "PEGASYS": 0.188270670385776, "PREVENAR": 10.67803554030242, "RIBAVIRIN": 1.7235242698772817, "SPIKEVAX": 0.0722337675285091, "SUFENTANIL": 4.77817246800226, "TAMIFLU": 3.810495463954853, "TOZINAMERAN": 0.2469788264210199, "VAXZEVRIA": 0.0780203202962056, "null": 2.3080786535534408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10188.json
new file mode 100644
index 00000000000..4a7f9a32eb3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10188.json
@@ -0,0 +1 @@
+{"null": 3.281272127559184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10189.json
new file mode 100644
index 00000000000..792daed4e35
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10189.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1019.json
index 7d11da5f9fa..0a636aa5fa8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1019.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1019.json
@@ -1 +1 @@
-{"null": 3.106548277458922}
\ No newline at end of file
+{"ELIQUIS": 4.3684327273159385, "HUMALOG": 8.959563217532247, "null": 1.123015281959476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10190.json
new file mode 100644
index 00000000000..d5c9c34f38f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10190.json
@@ -0,0 +1 @@
+{"null": 1.7085592046425129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10191.json
new file mode 100644
index 00000000000..9a3685450f8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10191.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 2.645049380968972, "ABATACEPT": 0.2820187082281151, "ADALIMUMAB": 0.2671449805563918, "AERIUS": 1.095366276818499, "AFINITOR": 0.4107314567195124, "AIMOVIG": 0.9573731661386912, "ALEMTUZUMAB": 0.5647212675737516, "ALIMTA": 1.772189770130102, "ANAKINRA": 0.3220613119581556, "APIDRA": 0.6175922100217691, "APIXABAN": 0.1057458737042549, "APREMILAST": 2.1632925714268985, "ARANESP": 0.4280769496511599, "ARAVA": 0.2392945206309047, "ATRIPLA": 0.0173164560443077, "AUBAGIO": 0.8354812223648952, "AVASTIN": 0.2186134903781338, "BENLYSTA": 0.58988818194601, "BETMIGA": 1.2645643009968444, "BIKTARVY": 0.5527971687815032, "BOSULIF": 1.3544901382597392, "BRAFTOVI": 0.3166481626986647, "BRILIQUE": 1.3555799206140176, "BRINTELLIX": 1.1004105201407564, "BRIVIACT": 0.691661096464124, "BUDESONIDE": 0.3116333069222899, "BYDUREON": 0.8311471597109628, "BYETTA": 0.1503793100069949, "CABOMETYX": 0.6724301151556972, "CELECOXIB": 0.4333836830117479, "CELLCEPT": 0.1347918528257182, "CHAMPIX": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10192.json
new file mode 100644
index 00000000000..6cd15dfae0b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10192.json
@@ -0,0 +1 @@
+{"AERIUS": 5.536016946949363, "ALIMTA": 1.8862529632048692, "ARAVA": 0.1120566199866317, "CHAMPIX": 1.5569145760866945, "CICLOSPORIN": 0.9445106724331775, "CIMZIA": 0.8075377730945118, "CLOPIDOGREL": 0.5071490481432297, "COMIRNATY": 0.3893763021285997, "COSENTYX": 1.0580215852826758, "COTELLIC": 11.840390810471607, "ENTYVIO": 1.681097830141845, "ERBITUX": 10.305356744041344, "GARDASIL": 0.4045846393675917, "GEFITINIB": 14.735475412541208, "IBUPROFEN": 1.2925212522104323, "IRESSA": 6.458981539309405, "IRINOTECAN": 4.362594473551276, "JARDIANCE": 0.6271159258980901, "KEPPRA": 1.1920172226811634, "KEYTRUDA": 0.4353320336891962, "LEVETIRACETAM": 1.1963107084225668, "LIXIANA": 4.269600279974583, "MEKINIST": 2.5134924073567397, "MMRVAXPRO": 1.3521884259168433, "NEXAVAR": 1.212912520334607, "OMALIZUMAB": 1.21395923712959, "PANITUMUMAB": 38.03705630434703, "PANTOPRAZOLE": 4.142917816608933, "PEGASYS": 1.923322399199337, "PLAVIX": 0.9163638510272888, "RINVOQ": 5.490306524150304, "ROACTEMRA": 1.7787767551454323, "SHINGRIX": 5.395340133803078, "SIMPONI": 1.5620971688543648, "SPIKEVAX": 0.3243966291354598, "STELARA": 2.5973101387200765, "SUTENT": 0.2347292597700376, "TOZINAMERAN": 0.142651729818155, "VAXZEVRIA": 0.1489127260798494, "VECTIBIX": 45.27706100547796, "XELJANZ": 0.5215136336093124, "ZELBORAF": 6.526124254759968, "ZOSTAVAX": 1.06239056931013, "null": 2.100538460550661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10193.json
new file mode 100644
index 00000000000..1ee225ca6ef
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10193.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1840829791507364, "MMRVAXPRO": 506.8084816369881, "null": 1.0835553831257816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10194.json
new file mode 100644
index 00000000000..3898f4e21ed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10194.json
@@ -0,0 +1 @@
+{"null": 3.4992262404136047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10195.json
new file mode 100644
index 00000000000..a46b6e8d89c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10195.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.2281691322734816, "AIMOVIG": 0.4011180415401929, "APROVEL": 2.316157012955151, "ARAVA": 0.2756291365497483, "BENLYSTA": 0.8196309888947786, "BRILIQUE": 1.023110034286203, "CHAMPIX": 0.32426783449911, "CICLOSPORIN": 0.6045833051540368, "CIMZIA": 0.2004857053233858, "COMIRNATY": 0.6844689303855755, "COSENTYX": 0.3443395470217258, "CYMBALTA": 0.1605806650465004, "DUPIXENT": 9.657588786118367, "ELIQUIS": 0.244318101822519, "FASLODEX": 0.8408593914254304, "GARDASIL": 0.6040838730640222, "INCIVO": 1.6969311343664524, "JAKAVI": 0.9352559160517914, "JARDIANCE": 0.8703271891962298, "KEYTRUDA": 0.3964637555027473, "MMRVAXPRO": 26.97762269354571, "NEXAVAR": 1.0662225438844048, "NIMENRIX": 2.379259540249586, "OMALIZUMAB": 0.8937619238389771, "PEGASYS": 0.4881301741263947, "PEGINTERFERON": 0.9815492457871704, "PEGINTRON": 0.5899721184616749, "RINVOQ": 0.9863090409007416, "ROACTEMRA": 1.7683711196878724, "SHINGRIX": 37.9863897226526, "SPIKEVAX": 0.5304134903219001, "STELARA": 0.4181354323422197, "STIVARGA": 1.6168382227848714, "SUTENT": 0.1231240968798134, "TOZINAMERAN": 0.6358431849531075, "VAXZEVRIA": 0.4798336116283321, "XELJANZ": 0.2444210104753963, "XOLAIR": 0.3942448261148148, "ZOSTAVAX": 29.708326729029046, "null": 1.3994479761745913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10196.json
new file mode 100644
index 00000000000..9977cee8e6f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10196.json
@@ -0,0 +1 @@
+{"null": 0.800415278061176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10197.json
new file mode 100644
index 00000000000..6b96f078e78
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10197.json
@@ -0,0 +1 @@
+{"AIMOVIG": 10.592901540881485, "AUBAGIO": 1.6869613548833846, "BENLYSTA": 2.549651254156743, "BETAFERON": 6.364718809565585, "COMIRNATY": 1.202168309536397, "ERENUMAB": 55.37720285797511, "EXFORGE": 2.516973718853111, "FASLODEX": 1.9200644165410816, "GARDASIL": 3.866568026699421, "LEFLUNOMIDE": 6.070559598029222, "LYRICA": 2.059392153594191, "METHOTREXATE": 1.1513942798494832, "PEGASYS": 1.6765907003794738, "PEGINTRON": 2.2664341551497014, "REVATIO": 3.034748316644695, "SIMPONI": 1.4195513668727555, "SPIKEVAX": 0.915438002281065, "STELARA": 1.042116141132692, "TOZINAMERAN": 1.40565468768742, "TRACLEER": 2.0397808543979017, "VAXZEVRIA": 1.1479187326856524, "XELJANZ": 0.8295269904109207, "XOLAIR": 0.7946958892479056, "ZOSTAVAX": 0.8833881165458032, "null": 0.9302416096715176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10198.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10198.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10199.json
new file mode 100644
index 00000000000..536d51d6a63
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10199.json
@@ -0,0 +1 @@
+{"null": 3.484806290653003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/102.json
index 88a8533af39..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/102.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 12.322723808550412, "COMBIVIR": 24.0434142335154, "CRIZOTINIB": 302.8494243972876, "DASATINIB": 74.04215963479666, "DOXORUBICIN": 33.07876840221489, "ERLOTINIB": 1461.8004258303438, "FULVESTRANT": 15.66309242300454, "GEFITINIB": 1332.9235146927251, "IRESSA": 69.7042989401872, "LAMIVUDINE": 33.238896139176376, "OSIMERTINIB": 1267.3087728740286, "TAGRISSO": 14.86060427971434}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1020.json
index e287ad16d60..a88548bcc0f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1020.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1020.json
@@ -1 +1 @@
-{"null": 2.0954861709124013}
\ No newline at end of file
+{"BEOVU": 93.67428826407624, "COMIRNATY": 0.5671262557679609, "SUBOXONE": 8.110760571375518, "TASIGNA": 16.568050196726247, "VAXZEVRIA": 0.3463376735473702, "null": 1.3333358353327571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10200.json
new file mode 100644
index 00000000000..a6e0e76eb00
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10200.json
@@ -0,0 +1 @@
+{"null": 3.06722183943413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10201.json
new file mode 100644
index 00000000000..6e5d229755e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10201.json
@@ -0,0 +1 @@
+{"APIDRA": 3.45542894978559, "BRINTELLIX": 17.125858481015793, "CLOPIDOGREL": 3.674654909838543, "COMIRNATY": 0.366919200566646, "GREPID": 197.4792364666786, "HEXYON": 158.01937603946033, "INFANRIX": 16.409262317848658, "MMRVAXPRO": 26.152224523580703, "PREVENAR": 27.348134156084345, "TOZINAMERAN": 1.0146632995833178, "VAXZEVRIA": 0.0686240238175913, "XELJANZ": 1.0648049452462018, "null": 2.816423534624055}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10202.json
new file mode 100644
index 00000000000..f93aedc0530
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10202.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 0.4551575514124741, "null": 0.9651982255024328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10203.json
new file mode 100644
index 00000000000..b9b7249ed4b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10203.json
@@ -0,0 +1 @@
+{"null": 2.653709282728216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10204.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10204.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10205.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10205.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10206.json
new file mode 100644
index 00000000000..76a45584b20
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10206.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4561108480268974, "null": 4.539416534563436}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10207.json
new file mode 100644
index 00000000000..45104be6e9b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10207.json
@@ -0,0 +1 @@
+{"NEXAVAR": 74.97237136613865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10208.json
new file mode 100644
index 00000000000..f7be4ec590f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10208.json
@@ -0,0 +1 @@
+{"null": 2.7373792987157866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10209.json
new file mode 100644
index 00000000000..35e518926a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10209.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2819242403505747, "GARDASIL": 3.653497583362144, "KEPPRA": 2.9139069923185583, "LANTUS": 1.968554072776224, "SPIKEVAX": 0.2140915494371843, "SUBOXONE": 10.20428945040482, "TOZINAMERAN": 0.7050046438665079, "VAXZEVRIA": 0.2084063051515612, "null": 2.381181248441305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1021.json
index d599d081baa..b1f291e4729 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1021.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1021.json
@@ -1 +1 @@
-{"AFINITOR": 51.08027883029757, "null": 2.467786338083004}
\ No newline at end of file
+{"COMIRNATY": 1.1479371445386235, "SPIKEVAX": 0.607510995801925, "null": 0.8313760879426951}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10210.json
new file mode 100644
index 00000000000..f376c167bb9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10210.json
@@ -0,0 +1 @@
+{"PANTOPRAZOLE": 201.8805340352618, "null": 1.9593720167416744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10211.json
new file mode 100644
index 00000000000..08a931031f8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10211.json
@@ -0,0 +1 @@
+{"AIMOVIG": 3.088697520970923, "ARIPIPRAZOLE": 5.104471160542829, "CICLOSPORIN": 6.317665971432981, "EFAVIRENZ": 14.25731724137022, "METHOTREXATE": 6.5436668042252055, "MIRVASO": 236.9391005386156, "OLANZAPINE": 6.25558060300266, "PLAVIX": 2.2484792954503834, "TENOFOVIR": 118.93981745434986, "null": 2.294384884340864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10212.json
new file mode 100644
index 00000000000..dca6a956fcb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10212.json
@@ -0,0 +1 @@
+{"null": 3.857120493859071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10213.json
new file mode 100644
index 00000000000..697d1f43cb9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10213.json
@@ -0,0 +1 @@
+{"COSENTYX": 161.2229417425015, "null": 0.4588045923273245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10214.json
new file mode 100644
index 00000000000..f393b3b55a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10214.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 106.8802633669788, "null": 1.1619192809764267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10215.json
new file mode 100644
index 00000000000..e1419248e0f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10215.json
@@ -0,0 +1 @@
+{"ALIMTA": 104.6420389196962, "CAPECITABINE": 50.10321851502408, "null": 0.277200086260331}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10216.json
new file mode 100644
index 00000000000..72542a53040
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10216.json
@@ -0,0 +1 @@
+{"VEKLURY": 59.47804175195003, "null": 57.29679367665796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10217.json
new file mode 100644
index 00000000000..ba4bec8f5fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10217.json
@@ -0,0 +1 @@
+{"CHAMPIX": 9.627420371106616, "HIZENTRA": 34.94568930985255, "IKERVIS": 223.1545420209044, "PRIVIGEN": 29.219136501435766, "VEKLURY": 83.13770294081219, "null": 8.225159035195468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10218.json
new file mode 100644
index 00000000000..39f6703118f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10218.json
@@ -0,0 +1 @@
+{"CIMZIA": 18.38263412236862, "ENTYVIO": 16.54140683664536, "PEGASYS": 5.259920454766123, "STELARA": 29.601740175848995, "SUTENT": 2.9271107066077224, "VOTRIENT": 12.622624450274008, "null": 0.335079122974743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10219.json
new file mode 100644
index 00000000000..c812402a8a9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10219.json
@@ -0,0 +1 @@
+{"BEVACIZUMAB": 47.87036523999608, "STELARA": 10.040194709607931, "STIVARGA": 49.00619672516794, "null": 0.1728989544698904}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1022.json
index 8306c5ea876..5ec79597266 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1022.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1022.json
@@ -1 +1 @@
-{"null": 1.2061406860951298}
\ No newline at end of file
+{"ABACAVIR": 0.1067825470820392, "ABASAGLAR": 0.1895026232307687, "ABATACEPT": 1.7782219966881074, "ABILIFY": 0.1521704746446708, "ABRAXANE": 0.283614755579585, "ACCOFIL": 1.1140641419599933, "ACETAMINOPHEN": 1.543898178348843, "ACLASTA": 1.4263823070646366, "ACLIDINIUM": 0.2367411426629639, "ADALIMUMAB": 1.3947297285405496, "ADCIRCA": 0.2522154429926096, "ADEFOVIR": 0.5131130957956538, "ADEMPAS": 0.629523248995703, "ADENURIC": 0.7460536848856453, "ADVATE": 0.353021188968146, "AERIUS": 0.2286472651197867, "AFINITOR": 0.3410068253772869, "AIMOVIG": 0.7073200249662395, "ALDARA": 1.0973368582439922, "ALEMTUZUMAB": 0.1566530438363255, "ALIMTA": 0.1345142011082987, "ALL": 0.1681305325069535, "AMBRISENTAN": 0.305465524853616, "AMIKACIN": 0.1021621349168139, "AMINOSALICYLIC": 0.4488241326834543, "ANAKINRA": 1.768385061960153, "ANORO": 0.0530174696987273, "APIDRA": 0.1289606388479956, "APIXABAN": 0.6144995636401512, "APREMILAST": 0.9878833591840114, "APREPITANT": 1.940709269161168, "APROVEL": 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0.4097877150750183, "BINOCRIT": 0.3022543095185359, "BLINCYTO": 0.3069836479373021, "BOCEPREVIR": 0.2351324542033983, "BONVIVA": 2.0490172957917334, "BOSENTAN": 0.1736442962591596, "BOSULIF": 0.5538440950090965, "BOSUTINIB": 0.4573890693474289, "BRAFTOVI": 0.6488413548199884, "BRILIQUE": 0.244621012545192, "BRINTELLIX": 0.9709678098626684, "BRIVIACT": 0.0744225600871479, "BRODALUMAB": 1.779302395175968, "BRUKINSA": 0.3019656201034623, "BUDESONIDE": 0.1988507505176027, "BUMETANIDE": 0.1310928699189678, "BUPIVACAINE": 0.2547985352591718, "BUPRENORPHINE": 0.1614546780982377, "BUSULFAN": 0.0298245962441116, "BUVIDAL": 0.3054990139720848, "BYDUREON": 0.9682508927516992, "BYETTA": 0.1952494249002876, "CABAZITAXEL": 0.1953488655243048, "CABOMETYX": 0.2249881828145006, "CABOTEGRAVIR": 0.391172850804773, "CAPECITABINE": 0.1390700650244888, "CAPRELSA": 0.2163919734153598, "CARFILZOMIB": 0.0801766929325628, "CASPOFUNGIN": 0.1243768353751357, "CELECOXIB": 0.5567342875583461, "CELLCEPT": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10220.json
new file mode 100644
index 00000000000..cdce5f2795f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10220.json
@@ -0,0 +1 @@
+{"AVASTIN": 8.654258959954422, "BEVACIZUMAB": 6.480852971909566, "ELIQUIS": 3.435335544291492, "HUMALOG": 2.0436252451464925, "JAKAVI": 4.393145243569486, "JARDIANCE": 1.7285965307265705, "MEPOLIZUMAB": 8.68915438638606, "SIMPONI": 3.135697264374766, "SPRYCEL": 5.135921517206346, "STELARA": 8.522347655480072, "STIVARGA": 49.09719744174818, "VECTIBIX": 32.906129050448705, "XELJANZ": 1.630036766133701, "null": 1.1671887003065309}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10221.json
new file mode 100644
index 00000000000..6cee7dce661
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10221.json
@@ -0,0 +1 @@
+{"AVASTIN": 51.1635121695772, "STIVARGA": 113.54632127258456, "null": 0.1963597593875509}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10222.json
new file mode 100644
index 00000000000..9e72bcd510e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10222.json
@@ -0,0 +1 @@
+{"AMINOSALICYLIC": 21.2759915879959, "null": 1.3841120534681108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10223.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10223.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10224.json
new file mode 100644
index 00000000000..277755a9615
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10224.json
@@ -0,0 +1 @@
+{"null": 0.721517212041183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10225.json
new file mode 100644
index 00000000000..9999d47e1f7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10225.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 3.683858190920003, "ADEMPAS": 1.3597940927922827, "AFINITOR": 0.3178967294490938, "AIMOVIG": 0.6591245851782536, "ALIGN": 39.60665694701842, "ALIMTA": 0.5480789836504809, "AMINOSALICYLIC": 20.57362400976395, "APIXABAN": 0.7274371474046262, "ARANESP": 0.5269681777411497, "ARAVA": 0.1752173081408782, "ARIXTRA": 6.291578025545048, "AUBAGIO": 0.3445759804176208, "AVAMYS": 10.580093144170958, "AVASTIN": 4.668556507379652, "AZATHIOPRINE": 0.9323020555852456, "AZILECT": 2.3938827784808345, "BEVACIZUMAB": 2.966031959831046, "BRAFTOVI": 2.3203354058294963, "BRILIQUE": 13.944299533675526, "BRINTELLIX": 0.632792555353528, "BUDESONIDE": 12.822351893438196, "BUPRENORPHINE": 0.218746216947352, "BUSULFAN": 0.5156737379867437, "BYETTA": 0.4679626444963248, "CABOMETYX": 0.3737419434003661, "CAPECITABINE": 0.4754053741918204, "CELLCEPT": 0.2626965293579187, "CHAMPIX": 1.2185351415815078, "CICLOSPORIN": 0.2646345073240116, "CIMZIA": 0.6715596792621273, "CINACALCET": 4.418707178753816, "CLOPIDOGREL": 5.52257751579966, "COMIRNATY": 0.1040755037042873, "COSENTYX": 1.115327302085288, "CYMBALTA": 0.6317240763290235, "CYTARABINE": 0.2196502715472644, "DABIGATRAN": 10.832610386304449, "DASATINIB": 4.753150628198638, "DEXAMETHASONE": 0.5093150347092136, "DIFICLIR": 4.142357476857005, "DUOPLAVIN": 18.933622390184794, "EFIENT": 5.9834468760417, "ELIQUIS": 10.781191874762293, "ENBREL": 0.1259266213495723, "ENOXAPARIN": 2.61097523996635, "ENTRESTO": 0.4162721137518344, "ENTYVIO": 5.318721343461029, "ESBRIET": 0.3103946047754048, "EXJADE": 1.4844219013270248, "FORSTEO": 0.6487740641721913, "GARDASIL": 0.2128968163127468, "HUMALOG": 0.1291737257756556, "HUMIRA": 3.059760340326412, "HYDROCORTISONE": 0.4007398678733662, "IBRANCE": 0.4287389005926219, "IBUPROFEN": 1.4727001076381203, "INCIVO": 4.506706422843994, "INFLECTRA": 6.264399374177301, "INFLIXIMAB": 17.368947854851182, "INLYTA": 0.7752494210083555, "IRBESARTAN": 0.8224711008110167, "JAKAVI": 0.2356850669583796, "JANUMET": 0.2548428564498759, "JARDIANCE": 0.11747042412718, "JEVTANA": 1.0042769281262751, "KALETRA": 0.6189665935156254, "KEPPRA": 0.3171598188237176, "KEYTRUDA": 0.24135689309601, "LANTUS": 0.0888001632804148, "LATUDA": 0.3556490971080986, "LEVOFLOXACIN": 0.1957517395899206, "LIXIANA": 14.00433180472529, "LONSURF": 1.7181646826494577, "MEKINIST": 0.3167893332303815, "METHOTREXATE": 0.2794079545772001, "MULTAQ": 0.8748473177380769, "MVASI": 4.942017048857083, "NEULASTA": 0.3744017673027205, "NEXAVAR": 1.1855620991548794, "NPLATE": 1.0072872851203396, "OCTREOTIDE": 6.984364082233032, "OFEV": 1.3336790006568569, "OLANZAPINE": 0.1979220942141428, "OPSUMIT": 0.4529534590188002, "PANTOPRAZOLE": 0.7469992290512284, "PEGASYS": 1.5887974107334275, "PEGINTERFERON": 1.8201151168505052, "PEGINTRON": 0.9417506934264068, "PLAVIX": 20.23558244392888, "PRADAXA": 21.964013991013093, "PRASUGREL": 11.713073360486606, "PREGABALIN": 6.6301361324604144, "REMICADE": 1.6699302898936357, "REVATIO": 0.6543079535626393, "RIBAVIRIN": 0.7372817397844426, "RINVOQ": 0.7905368133683629, "RITUXIMAB": 0.2420794594039605, "ROACTEMRA": 1.136069941087518, "ROTATEQ": 2.403234445151947, "RUBRACA": 0.6502832389689495, "RUCONEST": 1.646754243341796, "SAXENDA": 0.6337529818921533, "SIMPONI": 0.5940435522512594, "SOLIRIS": 0.7015509371886143, "SPIKEVAX": 0.095378017321728, "SPRYCEL": 1.3317048159772589, "STELARA": 0.8940083539850058, "STIVARGA": 1.8308355803710823, "SUTENT": 1.9463330475223, "TAMIFLU": 0.9236814243242348, "TASIGNA": 0.3852813546006228, "TICAGRELOR": 4.633215208097326, "TOVIAZ": 0.4271213208337607, "TOZINAMERAN": 0.2955386716707376, "TRACLEER": 0.7306809413092914, "TRULICITY": 0.2990172007008994, "VAXZEVRIA": 0.1482354930386801, "VELTASSA": 1.623090853833386, "VIAGRA": 0.3261468823638456, "VICTOZA": 0.5367577247972514, "VOTRIENT": 1.694569427916368, "XARELTO": 19.42164022474268, "XELJANZ": 3.449714732944801, "XOLAIR": 0.3325869116214479, "XTANDI": 0.6864643747140162, "YERVOY": 1.2154944990210983, "ZOSTAVAX": 0.3063210615995226, "ZYPREXA": 0.7296429745679748, "null": 1.2443407916523204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10226.json
new file mode 100644
index 00000000000..811d6156f06
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10226.json
@@ -0,0 +1 @@
+{"null": 3.160631548089909}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10227.json
new file mode 100644
index 00000000000..3c89f02cbfc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10227.json
@@ -0,0 +1 @@
+{"null": 0.4245000520692621}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10228.json
new file mode 100644
index 00000000000..9d6290e6d36
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10228.json
@@ -0,0 +1 @@
+{"null": 0.6967559409027245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10229.json
new file mode 100644
index 00000000000..09625d32d70
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10229.json
@@ -0,0 +1 @@
+{"null": 1.5345798162876387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1023.json
index ba3461faf4d..ebf8d203316 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1023.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1023.json
@@ -1 +1 @@
-{"KEYTRUDA": 23.02016556257564}
\ No newline at end of file
+{"ABACAVIR": 0.5207121866132853, "ABATACEPT": 5.742169223621758, "ABILIFY": 0.2897975018363046, "ACLASTA": 8.015668489391434, "ADALIMUMAB": 4.965949794510359, "AFINITOR": 0.2435453646628233, "AIMOVIG": 0.8188417171356166, "ALISKIREN": 14.818245905344613, "AMINOSALICYLIC": 2.52395774711242, "ANAKINRA": 3.010158760308475, "APIDRA": 0.2303363343979761, "ARAVA": 2.6019215335975114, "ATRIPLA": 0.8086752830126714, "AUBAGIO": 0.5426443688553872, "AVAMYS": 2.3688772918395093, "AVANDIA": 0.1070491750174446, "AVASTIN": 0.2333130502912452, "AVELUMAB": 4.3810188036593765, "AZATHIOPRINE": 2.2400656863007464, "BARICITINIB": 65.7265361981178, "BELIMUMAB": 11.67689489268312, "BENLYSTA": 2.818988549588164, "BIKTARVY": 0.3965284191483014, "BONVIVA": 1.229164500630474, "BOSULIF": 0.51475922687308, "BOTULINUM": 0.7751262012247254, "BRAFTOVI": 1.0184516012158609, "BUDESONIDE": 0.8089594894279345, "BYDUREON": 1.233801169126697, "BYETTA": 2.191877763533141, "CANNABIDIOL": 3.9038755677663466, "CELECOXIB": 3.4023720723841264, "CELLCEPT": 0.5742745307184555, "CHAMPIX": 0.1567427313626504, "CIALIS": 1.2347332930941584, "CICLOSPORIN": 1.1130984801781392, "CIMZIA": 2.0668807812810552, "CLOPIDOGREL": 1.0943157502354088, "COMIRNATY": 0.6016039701697437, "COSENTYX": 5.9382700498600665, "CYMBALTA": 0.6605590981267194, "DARUNAVIR": 1.695763712398257, "DASATINIB": 1.3922247815090136, "DEXAMETHASONE": 0.2649914999777463, "DOCETAXEL": 0.2113239488558369, "DULOXETINE": 0.6270740852540436, "DUPIXENT": 1.490330130310469, "ELIQUIS": 0.9995776444073688, "EMPAGLIFLOZIN": 1.3569397456679897, "ENBREL": 3.9782962012870393, "ENTRESTO": 0.2880103708883585, "ENTYVIO": 2.1640076405611333, "ERELZI": 5.06118021101964, "ESBRIET": 0.2228973950325995, "ESOMEPRAZOLE": 2.184281163993944, "ETANERCEPT": 2.171971249831496, "EVENITY": 0.9463497781634492, "EVISTA": 1.814816309850581, "EXFORGE": 0.5418612079072718, "EXJADE": 0.2293764121263069, "FASENRA": 1.069103655141585, "FASLODEX": 1.6362340285838504, "FENTANYL": 0.5258406727707465, "FLUTICASONE": 2.421022889394436, "FORSTEO": 0.6573845534337465, "FORXIGA": 0.2641143527955493, "GARDASIL": 0.7429056215416953, "GLYCOPYRRONIUM": 3.065367556652224, "GOLIMUMAB": 6.00074716211868, "HIZENTRA": 0.552573839699496, "HUMALOG": 3.2926881945950206, "HUMIRA": 5.591365302742274, "HYDROCORTISONE": 1.27143983061637, "IBRANCE": 1.4525113308302466, "IBUPROFEN": 0.8240831028761719, "IDACIO": 12.91222712264465, "ILARIS": 3.642187158944324, "INFLECTRA": 3.0589052773900134, "INFLIXIMAB": 1.4195369010977772, "INLYTA": 0.5645655702162626, "INSULIN": 0.9164862771939696, "INTRONA": 0.8050923708996068, "IPILIMUMAB": 5.236890875852426, "ISENTRESS": 0.9055164598955112, "JANUMET": 1.8184218380802757, "JANUVIA": 1.5903398294811029, "JARDIANCE": 0.0754021722284155, "KAFTRIO": 0.562602455517647, "KEPPRA": 0.2383086109839427, "KEYTRUDA": 1.5429048895713764, "LANTUS": 1.3941235188403585, "LEFLUNOMIDE": 5.491057816260588, "LEVEMIR": 1.3236826530549894, "LEVOFLOXACIN": 0.6623004698512472, "LYRICA": 1.3170580045465607, "MEKINIST": 0.3705389358781134, "MEPOLIZUMAB": 1.5298885916467004, "METHOTREXATE": 3.651873205586637, "MICARDIS": 0.4033364472443396, "MMRVAXPRO": 0.949253279928264, "MODERNA": 0.3243217960162788, "MYCOPHENOLATE": 0.6810467048428882, "NEXAVAR": 0.0839126130066938, "NIMENRIX": 0.4989768955785431, "NPLATE": 0.5260916557780032, "NUCALA": 0.5275866516723605, "OFEV": 0.3750738717420096, "OMALIZUMAB": 1.3267820872324805, "OPDIVO": 1.6585852928383196, "OPSUMIT": 0.6816457371675841, "OPTIMARK": 0.1989623716005877, "ORENCIA": 3.425918491940197, "OXYBUTYNIN": 1.6720183725286712, "PANTOPRAZOLE": 0.4764275808912839, "PEGASYS": 0.9415139332083114, "PEGINTRON": 0.8295780148097617, "PEMBROLIZUMAB": 1.768062087236013, "PLAVIX": 0.4385175947692855, "PROLIA": 3.1474188356173176, "REMICADE": 1.3576747023406657, "REVATIO": 1.1364568774721473, "RINVOQ": 3.239781860498574, "RITUXIMAB": 1.650957885230226, "ROACTEMRA": 4.569417940440983, "RUBRACA": 0.8149588035435082, "SHINGRIX": 0.9561476872115438, "SIMPONI": 5.309385647707847, "SKYRIZI": 2.6536412187940126, "SOLIRIS": 0.3721297873726514, "SPIKEVAX": 0.376710398374793, "SPRYCEL": 0.2536575715155709, "STELARA": 3.033935403295335, "STRIBILD": 0.60020974471422, "SUBOXONE": 0.365021061295918, "SUTENT": 0.5010606413921248, "TASIGNA": 0.727088156657595, "TOCILIZUMAB": 4.69499557032757, "TOVIAZ": 1.4621524311973704, "TOZINAMERAN": 1.1878778144916404, "TRELEGY": 0.5940127811126027, "TREMFYA": 3.6619584120971513, "TRULICITY": 0.6901932250859575, "TRUVADA": 0.5350987643902502, "TWINRIX": 1.6449567751950855, "USTEKINUMAB": 5.884095841308956, "VAXZEVRIA": 0.4615941631582295, "VEDOLIZUMAB": 4.097538891715336, "VIAGRA": 1.2139265931098584, "VICTOZA": 0.5100614682022842, "VIREAD": 0.4038775876244952, "XARELTO": 0.7652141609941534, "XELJANZ": 4.122081558731002, "XOLAIR": 1.3863581255101256, "XTANDI": 0.8788112569358478, "XYREM": 2.431628755455323, "ZOMETA": 2.0453810811446984, "ZOSTAVAX": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10230.json
new file mode 100644
index 00000000000..56ab14f86ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10230.json
@@ -0,0 +1 @@
+{"AVASTIN": 181.97170946830076, "KEYTRUDA": 10.672636963476972, "null": 0.5336009134479851}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10231.json
new file mode 100644
index 00000000000..1f20b2a6513
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10231.json
@@ -0,0 +1 @@
+{"null": 5.374717832091051}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10232.json
new file mode 100644
index 00000000000..651037d7505
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10232.json
@@ -0,0 +1 @@
+{"ACLASTA": 225.0546184347296, "MIRABEGRON": 320.3578260631208, "null": 1.404769050491121}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10233.json
new file mode 100644
index 00000000000..1aca93182d1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10233.json
@@ -0,0 +1 @@
+{"null": 1.9278468846850445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10234.json
new file mode 100644
index 00000000000..943f17f8d2e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10234.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1601225980609471, "ENTYVIO": 11.864065952640306, "INCIVO": 33.8738037951446, "LANTUS": 3.1311924691670328, "VEDOLIZUMAB": 167.032954129367, "null": 1.43039230472952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10235.json
new file mode 100644
index 00000000000..6b4804b3460
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10235.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 4.17733007051339, "PEGASYS": 1.9578516551790488, "SUTENT": 3.145071589462309, "null": 1.4102971606259669}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10236.json
new file mode 100644
index 00000000000..a413379346a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10236.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 13.956680819426806, "ELIQUIS": 12.140180069307052, "null": 0.8125144528876719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10237.json
new file mode 100644
index 00000000000..69732ff7864
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10237.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": 21.326550053487267, "null": 0.8102443015074874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10238.json
new file mode 100644
index 00000000000..c51be745f40
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10238.json
@@ -0,0 +1 @@
+{"null": 0.3036851220416282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10239.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10239.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1024.json
index 46140a40142..b49973be1eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1024.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1024.json
@@ -1 +1 @@
-{"ATAZANAVIR": 54.7351435884485, "BUDESONIDE": 13.218166422979383, "KEYTRUDA": 32.04578747602121, "OPDIVO": 62.27091645409207, "null": 1.0192337198319297}
\ No newline at end of file
+{"null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10240.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10240.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10241.json
new file mode 100644
index 00000000000..53c19939544
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10241.json
@@ -0,0 +1 @@
+{"BRIDION": 7063.147091676085, "SUGAMMADEX": 1591.5272849619423, "null": 0.2486167999940189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10242.json
new file mode 100644
index 00000000000..cde86f41b6d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10242.json
@@ -0,0 +1 @@
+{"AFINITOR": 6.722234962891587, "BUSULFAN": 12.877251636730543, "CAPECITABINE": 35.540432407836505, "COMIRNATY": 0.0378009967871722, "CYTARABINE": 4.344231902568605, "FASLODEX": 12.050339317952336, "HERCEPTIN": 12.4395004226943, "IMATINIB": 26.60677371133636, "KEYTRUDA": 8.020189305006207, "LYNPARZA": 34.686911872857614, "MEKINIST": 14.22219484898548, "NEULASTA": 19.03528406823949, "RITUXIMAB": 10.232998949904122, "RUBRACA": 42.9710601906414, "TAGRISSO": 10.40935008333442, "TEMODAL": 24.547397118912546, "TEMOZOLOMIDE": 27.349213887157944, "VOTRIENT": 7.1166075887003535, "null": 0.5994886970639964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10243.json
new file mode 100644
index 00000000000..b8adcd16b7e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10243.json
@@ -0,0 +1 @@
+{"ADENURIC": 75.97041186478117, "ARANESP": 8.723705557334297, "CICLOSPORIN": 5.910104567285263, "COMBIVIR": 24.448978223515923, "COMIRNATY": 0.0995077838856435, "PEGASYS": 6.155601416996599, "SUTENT": 2.321015019291003, "null": 1.096434479339737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10244.json
new file mode 100644
index 00000000000..aa38c531f9c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10244.json
@@ -0,0 +1 @@
+{"null": 1.2714126242747026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10245.json
new file mode 100644
index 00000000000..bca69927eaf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10245.json
@@ -0,0 +1 @@
+{"IBRANCE": 14.155550118731448, "KEYTRUDA": 3.7391436938121454, "PEGASYS": 3.7122073522632566, "null": 0.9770504967657448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10246.json
new file mode 100644
index 00000000000..f6b8eb5cee7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10246.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.7739552238354577, "ADALIMUMAB": 1.066930761542659, "ADENURIC": 3.825161184222963, "AFINITOR": 2.3737943282564853, "ALEMTUZUMAB": 0.8310815444901052, "ALIMTA": 1.7153356594958793, "AMINOSALICYLIC": 2.3403199476624468, "ARANESP": 1.6622223632632749, "ARAVA": 0.2932308953839781, "ARIPIPRAZOLE": 2.692430227343563, "AUBAGIO": 0.3614890137201618, "AVANDIA": 0.3045222012463022, "AVASTIN": 1.2748101677630477, "BEDAQUILINE": 1.752064600144597, "BEVACIZUMAB": 2.5022512432525645, "BLINCYTO": 12.054738877525292, "BOCEPREVIR": 4.92110523420947, "BOSULIF": 2.492275087211099, "BRAFTOVI": 0.867725361737343, "BRILIQUE": 1.7338779128153277, "CABOMETYX": 0.6974908715618722, "CAPECITABINE": 1.8878620535326749, "CELLCEPT": 0.8730232572708189, "CICLOSPORIN": 0.939731011530932, "CIMZIA": 0.2008602081531137, "CLOPIDOGREL": 1.353141194451172, "COMBIVIR": 1.4086370586306665, "COMIRNATY": 0.0728926163802517, "COMTAN": 2.3194771085177304, "COSENTYX": 0.2542611707756005, "CYMBALTA": 0.2018170242413837, "CYTARABINE": 0.5581009055839451, "DARZALEX": 1.3475949172818575, "DEXAMETHASONE": 1.3063367156251553, "DOCETAXEL": 1.82006592817303, "DOXORUBICIN": 3.606995105170477, "ELIQUIS": 1.1722223677239691, "ENBREL": 0.46789154600341, "ENTRESTO": 1.752081784804584, "ENTYVIO": 0.5817813156198675, "EXFORGE": 0.7274418602625438, "EXJADE": 5.257653590865671, "FASLODEX": 4.756003783202669, "FORSTEO": 1.175181492104447, "FULVESTRANT": 4.045702736729371, "GANCICLOVIR": 1.9321533301976503, "GARDASIL": 0.1431746783613318, "GLIVEC": 2.623605299030118, "HALAVEN": 2.330319721118961, "HERCEPTIN": 2.6331414665676496, "HUMIRA": 0.8118661549653398, "HYCAMTIN": 59.5453019001828, "IBRANCE": 16.875308788060785, "ICLUSIG": 2.3439505318834817, "INCIVO": 1.19522186726591, "INFERGEN": 16.823621327997, "INTELENCE": 6.131405407137554, "JAKAVI": 6.556104982169239, "KEPPRA": 0.5029524790834108, "KEYTRUDA": 0.6380157678465033, "KISQALI": 2.487172250706836, "KYMRIAH": 5.592592327324308, "LANTUS": 0.1116158502570439, "LEMTRADA": 3.3692793669814365, "LEVOFLOXACIN": 0.3325939626704222, "LONSURF": 8.974819528740571, "LYNPARZA": 5.51348373286463, "LYRICA": 0.6349730693350717, "MABTHERA": 1.8703111315133645, "MEPOLIZUMAB": 1.1465486742152118, "METFORMIN": 7.5991257544354385, "METHOTREXATE": 1.242441771143436, "NEULASTA": 2.408527315012829, "NINLARO": 2.693605988565964, "OLANZAPINE": 0.4569147288722259, "OLAPARIB": 5.355463297249801, "OMALIZUMAB": 0.6915852827888173, "OPSUMIT": 1.6908997621341428, "OZEMPIC": 7.234020149227523, "PEGASYS": 19.262463026304136, "PEGINTERFERON": 2.1769398448989614, "PEGINTRON": 7.588078949916194, "PEMETREXED": 1.969032523216012, "PLAVIX": 1.8608709554170515, "PRADAXA": 3.816201780561157, "RASILEZ": 1.8018691426527444, "REVLIMID": 3.9319069787608902, "RIBAVIRIN": 2.548765900302668, "RINVOQ": 0.8000624250861356, "RITUXIMAB": 0.3989916528996338, "RUBRACA": 18.509743577598037, "RUXOLITINIB": 6.181037183481511, "SOLIRIS": 3.362311482217105, "SPIKEVAX": 0.037748496609769, "SPRYCEL": 3.0576929227133136, "STIVARGA": 0.508087527952557, "SUTENT": 3.086688881851058, "TAMIFLU": 0.5001153593603113, "TASIGNA": 1.4093494697187925, "TEGAFUR": 15.814446673867652, "TOPOTECAN": 8.22848145155893, "TOZINAMERAN": 0.2044774485640453, "TRACLEER": 0.910070046129873, "VAXZEVRIA": 0.015058866881256, "VFEND": 0.72385253508897, "VOTRIENT": 0.8527059512639211, "XARELTO": 1.0121288246694375, "XELJANZ": 1.503489929687304, "XOFIGO": 3.675930822729843, "XTANDI": 0.7230657533985765, "ZIAGEN": 5.033734481746527, "ZOMETA": 4.146037488744774, "ZOSTAVAX": 0.3575816460847121, "ZYPREXA": 1.0291824052457803, "null": 1.0355043931218089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10247.json
new file mode 100644
index 00000000000..6ccdafe277d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10247.json
@@ -0,0 +1 @@
+{"BEDAQUILINE": 15.872177732558368, "COMIRNATY": 0.2551605712314874, "JAKAVI": 21.943196076681197, "JARDIANCE": 3.485486109505033, "KEYTRUDA": 2.2000650695922754, "MEPOLIZUMAB": 9.140829037386766, "OLANZAPINE": 3.3469815599066566, "PEGASYS": 2.1716365869484715, "SUTENT": 1.0816035221351614, "TOZINAMERAN": 0.8886343992802235, "VAXZEVRIA": 0.1345366759138752, "null": 0.8430614924821966}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10248.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10248.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10249.json
new file mode 100644
index 00000000000..7235cffca44
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10249.json
@@ -0,0 +1 @@
+{"ZYPREXA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1025.json
index b9628684524..7344c5157ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1025.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1025.json
@@ -1 +1 @@
-{"KEYTRUDA": 31.93314759589543, "null": 1.1478113270909147}
\ No newline at end of file
+{"ADALIMUMAB": 0.3732191833078223, "ARAVA": 1.7481617866066252, "CASPOFUNGIN": 15.579829609146616, "CELLCEPT": 2.011428569992564, "CICLOSPORIN": 1.598220513414094, "CIMZIA": 3.5163504461458084, "COMIRNATY": 0.03804358547989, "COSENTYX": 3.3910701691494656, "DAPTOMYCIN": 61.70225519680322, "ELIQUIS": 1.2647598073697788, "ENBREL": 3.0330760683879, "FENTANYL": 2.8711047605091102, "HUMIRA": 5.979335821705668, "METHOTREXATE": 11.703663942173794, "PEGASYS": 2.023159462034352, "PEGINTRON": 2.976347410812122, "RINVOQ": 3.579710145998364, "ROACTEMRA": 52.76024810048053, "SIMPONI": 9.186060613551158, "SPIKEVAX": 0.0845410637446171, "STELARA": 1.4133293267323928, "VAXZEVRIA": 0.1180925495022592, "XELJANZ": 3.644751005460785, "null": 1.0415597047268486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10250.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10250.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10251.json
new file mode 100644
index 00000000000..9250588bf59
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10251.json
@@ -0,0 +1 @@
+{"PEGASYS": 20.63941900416405, "null": 0.4491125594149601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10252.json
new file mode 100644
index 00000000000..fdbe166898c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10252.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 80.51313070162348, "SOLIRIS": 57.93569704911656, "null": 0.5244048682933069}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10253.json
new file mode 100644
index 00000000000..188e2bb9138
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10253.json
@@ -0,0 +1 @@
+{"ABATACEPT": 30.0403683165922, "ADALIMUMAB": 14.774755516347254, "APREMILAST": 447.2689026325131, "null": 0.1275183902611697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10254.json
new file mode 100644
index 00000000000..9be419f935d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10254.json
@@ -0,0 +1 @@
+{"ABATACEPT": 11.229667801459438, "ACLASTA": 62.00997749526741, "ADALIMUMAB": 13.83176222551922, "ANAKINRA": 160.41481570885662, "APREMILAST": 5.828459560207387, "ARAVA": 21.833924620604584, "AZATHIOPRINE": 21.615674350925325, "CELLCEPT": 3.021997516263152, "CERTOLIZUMAB": 73.63894661296554, "CICLOSPORIN": 4.07576413751004, "CIMZIA": 5.548144461721787, "COSENTYX": 5.640356935166621, "ENBREL": 45.70794230793286, "VAXZEVRIA": 0.0410718541222782, "null": 0.0538575036949801}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10255.json
new file mode 100644
index 00000000000..423d527d97b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10255.json
@@ -0,0 +1 @@
+{"ANAKINRA": 72.47265481154687, "CARIPRAZINE": 2121.8609380328053, "HUMIRA": 38.96867419144685, "null": 0.5041573185859929}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10256.json
new file mode 100644
index 00000000000..29363649465
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10256.json
@@ -0,0 +1 @@
+{"ABATACEPT": 5.467282779962984, "ADALIMUMAB": 4.041393089831988, "AMIKACIN": 3.918920902624868, "ANAKINRA": 56.95258659095852, "APREMILAST": 6.650550715651783, "ARAVA": 5.355240860022168, "AZATHIOPRINE": 3.5418457837800763, "BUDESONIDE": 1.862477576321848, "CELLCEPT": 0.9967125645526136, "CHAMPIX": 0.4392415690363377, "CICLOSPORIN": 4.476865567359869, "CIMZIA": 1.8421102963692184, "CLOPIDOGREL": 0.4966344096028836, "COAPROVEL": 2.434359530230981, "COMBIVIR": 1.9893679870621264, "COMIRNATY": 0.2145535626632737, "COMTAN": 11.715200002693567, "COSENTYX": 3.835069659565691, "CYMBALTA": 0.246308123744785, "DEXAMETHASONE": 0.7943193279090702, "ELIQUIS": 0.1991226104667976, "ENBREL": 26.93217104467422, "ENTRESTO": 1.190245770417906, "ENTYVIO": 1.7780856333014152, "EXFORGE": 2.223274593071863, "FORSTEO": 0.7370978448026361, "GARDASIL": 0.9263180950700228, "HUMIRA": 9.502806104864453, "KEPPRA": 0.5830635782534382, "LEFLUNOMIDE": 12.453092877441405, "LEVOFLOXACIN": 0.9470640722266648, "METHOTREXATE": 3.390278011525089, "NEXAVAR": 0.5492766281895222, "OLANZAPINE": 1.0501378764933504, "PEGASYS": 0.8306910497810184, "PEGINTRON": 0.6110298527959026, "PLAVIX": 0.4475530894051869, "RINVOQ": 2.379149599534041, "RITUXIMAB": 1.363744433932086, "ROACTEMRA": 1.37447012300721, "SIMPONI": 2.2621064168753464, "SPIKEVAX": 0.1139882837777011, "STELARA": 0.5987064453667637, "SUTENT": 0.1490500456576461, "TELMISARTAN": 9.898958802959395, "TOZINAMERAN": 0.6610229597127024, "VAXZEVRIA": 0.1074697382764747, "XELJANZ": 7.056912201663936, "XOLAIR": 1.0126776447584818, "ZOSTAVAX": 0.5188723567183828, "ZYPREXA": 0.4936334035061955, "null": 0.8820715951452008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10257.json
new file mode 100644
index 00000000000..0d49d3f7af6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10257.json
@@ -0,0 +1 @@
+{"EXJADE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10258.json
new file mode 100644
index 00000000000..100f0a54d16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10258.json
@@ -0,0 +1 @@
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10259.json
new file mode 100644
index 00000000000..b4e7144340e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10259.json
@@ -0,0 +1 @@
+{"PRIVIGEN": 457.4290938374648, "null": 1.1414082821232734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1026.json
index c67d4c392f3..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1026.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1026.json
@@ -1 +1 @@
-{"ABACAVIR": 1.3960511230350103, "AFINITOR": 1.7902133183868572, "ATRIPLA": 4.103694418045182, "CICLOSPORIN": 1.3841221604784528, "CLOPIDOGREL": 1.836058877653047, "DENOSUMAB": 20.313165597450908, "ENTRESTO": 13.36585830485748, "EXJADE": 2.4061117849041787, "FORXIGA": 12.144871828577896, "JARDIANCE": 3.140052707638863, "KEYTRUDA": 1.1069036211219168, "RASILEZ": 7.777418992279464, "REVATIO": 5.492073195898689, "STRIBILD": 3.9269584221099176, "SUTENT": 2.75239839647671, "TRUVADA": 7.446884595025429, "null": 1.0292150492484766}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10260.json
new file mode 100644
index 00000000000..05fc4b93476
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10260.json
@@ -0,0 +1 @@
+{"ELIQUIS": 29.06653824658213, "KEYTRUDA": 4.1600996866476585, "OPSUMIT": 26.231119369316023, "PEGASYS": 2.3889335889434657, "PEGINTERFERON": 11.510305786449738, "PEGINTRON": 4.520038591047882, "SOLIRIS": 24.23960366575733, "TRACLEER": 16.84039354442232, "null": 0.4948239631383519}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10261.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10261.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10262.json
new file mode 100644
index 00000000000..c8feef5a16d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10262.json
@@ -0,0 +1 @@
+{"null": 1.1251644291338774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10263.json
new file mode 100644
index 00000000000..002850202a3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10263.json
@@ -0,0 +1 @@
+{"ADENURIC": 109.21631177962252, "ALEMTUZUMAB": 46.00479487808789, "COMIRNATY": 0.1825303676179422, "LEMTRADA": 46.658476293052544, "null": 0.8797037733824712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10264.json
new file mode 100644
index 00000000000..1eb0db42793
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10264.json
@@ -0,0 +1 @@
+{"null": 0.6017316018275947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10265.json
new file mode 100644
index 00000000000..bf159948e81
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10265.json
@@ -0,0 +1 @@
+{"ABATACEPT": 69.3679888439009, "ADALIMUMAB": 4.952821055672592, "COMIRNATY": 0.3702118786176727, "null": 0.2435226415735424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10266.json
new file mode 100644
index 00000000000..033e6c1ec2c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10266.json
@@ -0,0 +1 @@
+{"ABATACEPT": 2.506582333461751, "ADALIMUMAB": 0.3825488931787463, "AFINITOR": 6.215444124540385, "AIMOVIG": 2.428190349482612, "ALEMTUZUMAB": 8.266113922647603, "ARAVA": 2.0390502973786004, "ARIPIPRAZOLE": 21.72571102155434, "AVASTIN": 3.7881876508101664, "CICLOSPORIN": 1.856650439965148, "CIMZIA": 0.9568012500651438, "COMIRNATY": 0.0690902367219972, "COSENTYX": 1.6442785425676436, "DOCETAXEL": 7.109199533740688, "DULOXETINE": 11.593225283906843, "EMEND": 22.663905494117028, "ENBREL": 1.8835541455089109, "ENTRESTO": 11.609380249174064, "EXJADE": 13.174959563335372, "IBRANCE": 7.305769321759988, "JAKAVI": 15.070755496723075, "KEYTRUDA": 1.3529566813531215, "KYMRIAH": 9.114433446266275, "LEMTRADA": 9.215695086589596, "METHOTREXATE": 3.889591593812476, "OLANZAPINE": 1.6234215805825207, "PEGASYS": 1.6311945981470504, "RIVAROXABAN": 29.471489672709158, "RUXOLITINIB": 18.3639300344472, "SOLIRIS": 4.153040394037764, "SUTENT": 1.1601778503600295, "TOZINAMERAN": 0.2403805858839064, "VOTRIENT": 2.5339163914717275, "XELJANZ": 3.271306591614134, "ZOSTAVAX": 2.25227618085038, "null": 0.3860003250460489}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10267.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10267.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10268.json
new file mode 100644
index 00000000000..e58c6ad1f02
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10268.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3337845630774006, "DULOXETINE": 33.313117930687774, "OLANZAPINE": 11.513979003407526, "TOZINAMERAN": 0.8196047387057283, "VAXZEVRIA": 0.1584219879614279, "ZYPREXA": 6.65388253231199, "null": 1.9286812440553869}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10269.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10269.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1027.json
index ab8490a5858..5027eeaaeba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1027.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1027.json
@@ -1 +1 @@
-{"null": 2.569455383556475}
\ No newline at end of file
+{"CASPOFUNGIN": 633.1345390859295, "null": 0.5033462095138237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10270.json
new file mode 100644
index 00000000000..1737d5c7b68
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10270.json
@@ -0,0 +1 @@
+{"null": 1.4672362888092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10271.json
new file mode 100644
index 00000000000..60a9fbdfe88
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10271.json
@@ -0,0 +1 @@
+{"INFANRIX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10272.json
new file mode 100644
index 00000000000..d112725e096
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10272.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3147322969270982, "CYMBALTA": 3.0824454475329643, "VAXZEVRIA": 0.241385019161297, "null": 1.813184828284205}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10273.json
new file mode 100644
index 00000000000..5b291695cb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10273.json
@@ -0,0 +1 @@
+{"ACTOS": 43.2603399575675, "COMIRNATY": 0.277395536847231, "COSENTYX": 7.209975275695566, "FORSTEO": 5.97991362414407, "GARDASIL": 2.867914524971113, "SUTENT": 7.967462976393679, "TOZINAMERAN": 0.747185185050734, "VAXZEVRIA": 0.4101854180535112, "null": 1.2003253736657455}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10274.json
new file mode 100644
index 00000000000..0e7166f2ae7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10274.json
@@ -0,0 +1 @@
+{"MEPOLIZUMAB": 56.08987901972864, "null": 1.0172532373180796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10275.json
new file mode 100644
index 00000000000..c75bb2665ca
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10275.json
@@ -0,0 +1 @@
+{"AMINOSALICYLIC": 46.7131363565164, "null": 1.637266105240185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10276.json
new file mode 100644
index 00000000000..230d411951b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10276.json
@@ -0,0 +1 @@
+{"ELTROMBOPAG": 3205.272250944176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10277.json
new file mode 100644
index 00000000000..bc9cb93746c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10277.json
@@ -0,0 +1 @@
+{"CYTARABINE": 133.0906916254109}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10278.json
new file mode 100644
index 00000000000..9263fa5f5ac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10278.json
@@ -0,0 +1 @@
+{"SYNAGIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10279.json
new file mode 100644
index 00000000000..429ac5dc0c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10279.json
@@ -0,0 +1 @@
+{"ABILIFY": 10.88302855754626, "DACLATASVIR": 164.33060163135738, "EYLEA": 13.901648158701931, "NPLATE": 28.88365778285081, "null": 1.4250011344096505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1028.json
index 9c3843db0b5..7f85ff3f926 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1028.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1028.json
@@ -1 +1 @@
-{"null": 1.6089106389006531}
\ No newline at end of file
+{"ARAVA": 7.513257798899215, "CIMZIA": 3.4372175831677723, "COMIRNATY": 0.0414150698019485, "CYMBALTA": 1.1099583580039212, "ELIQUIS": 1.0040253747707355, "ENBREL": 3.883871485230878, "HUMIRA": 5.917856987651562, "ILARIS": 363.0507514653518, "IRON": 22.43218102530886, "METHOTREXATE": 4.323509405664458, "ROACTEMRA": 12.05821172968112, "SIMPONI": 7.436339310365863, "SUBOXONE": 2.4928157894274574, "SUTENT": 0.6052467492970766, "XELJANZ": 14.234747362683532, "null": 0.926214143768222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10280.json
new file mode 100644
index 00000000000..06d2016b155
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10280.json
@@ -0,0 +1 @@
+{"null": 1.5954830777607971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10281.json
new file mode 100644
index 00000000000..c4a4d7a83e8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10281.json
@@ -0,0 +1 @@
+{"APREPITANT": 58.52446894248711, "CLOPIDOGREL": 3.095153148062004, "COMIRNATY": 0.1408719893709024, "JANUMET": 3.118602151108715, "ROTATEQ": 47.10181395724627, "SAXENDA": 5.1606517877427525, "SPIKEVAX": 0.1250734729971861, "SUTENT": 1.6327936827627154, "TRULICITY": 5.142525928562297, "VAXZEVRIA": 0.1037423547608511, "VOTRIENT": 2.9108483682325774, "XTANDI": 2.222294789879967, "null": 2.175749998761863}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10282.json
new file mode 100644
index 00000000000..27292f3fdcd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10282.json
@@ -0,0 +1 @@
+{"ARANESP": 7.601391093911192, "INCRUSE": 48.49524189841461, "OPSUMIT": 20.04430785900896, "TRELEGY": 30.597670684622624, "VELTASSA": 45.52358652067237, "VOTRIENT": 11.638223904488884, "null": 2.009575679377955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10283.json
new file mode 100644
index 00000000000..55c409669be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10283.json
@@ -0,0 +1 @@
+{"STELARA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10284.json
new file mode 100644
index 00000000000..166589e4f64
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10284.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5530338257805416, "null": 0.6096614320622229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10285.json
new file mode 100644
index 00000000000..ae2b709d184
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10285.json
@@ -0,0 +1 @@
+{"AUBAGIO": 37.09277527668204, "COMIRNATY": 0.9061266313578832, "GARDASIL": 7.419074552804084, "KESIMPTA": 141.534833756436, "SPIKEVAX": 0.6374095769926913, "null": 0.21132153007929}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10286.json
new file mode 100644
index 00000000000..49bb5770829
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10286.json
@@ -0,0 +1 @@
+{"KYMRIAH": 95.7618000705373, "RIBAVIRIN": 59.43979644407972, "RITUXIMAB": 132.9172752129024, "SIMEPREVIR": 615.722476591015, "null": 0.1269585889764614}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10287.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10287.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10288.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10288.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10289.json
new file mode 100644
index 00000000000..851600929ef
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10289.json
@@ -0,0 +1 @@
+{"SKYRIZI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1029.json
index 980450bfe62..de664275ac6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1029.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1029.json
@@ -1 +1 @@
-{"HEPSERA": 37.52840267058623, "KEYTRUDA": 2.0888918106477794, "OLANZAPINE": 3.908728399079709, "ZYPREXA": 2.370075140237085, "null": 1.743346267146675}
\ No newline at end of file
+{"COMIRNATY": 2.983283030680931, "GARDASIL": 4.487941083354287, "SPIKEVAX": 1.7630396234078285, "TOZINAMERAN": 3.6002155017639565, "VAXZEVRIA": 1.315774392030676, "null": 0.3083338637251893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10290.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10290.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10291.json
new file mode 100644
index 00000000000..5a45fa881a7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10291.json
@@ -0,0 +1 @@
+{"HIZENTRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10292.json
new file mode 100644
index 00000000000..8ec824599be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10292.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 78.90608863814782}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10293.json
new file mode 100644
index 00000000000..372802cc4d6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10293.json
@@ -0,0 +1 @@
+{"ATRIPLA": 1.7499796226134294, "FORXIGA": 16.18712503379913, "INVOKANA": 85.79578053450582, "JARDIANCE": 15.967653044820963, "ROACTEMRA": 14.472874538595448, "XALKORI": 63.46430004001686, "null": 0.4924510578364075}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10294.json
new file mode 100644
index 00000000000..fec1d876ba1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10294.json
@@ -0,0 +1 @@
+{"null": 0.68141364394783}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10295.json
new file mode 100644
index 00000000000..330605f0492
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10295.json
@@ -0,0 +1 @@
+{"null": 0.4398222174996861}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10296.json
new file mode 100644
index 00000000000..4fa6cc0fd6a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10296.json
@@ -0,0 +1 @@
+{"ATAZANAVIR": 32.286381991134014, "KEPPRA": 7.225910540702944, "null": 3.5684123221757886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10297.json
new file mode 100644
index 00000000000..de610208962
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10297.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 38.848734903639006, "null": 0.5143141970941679}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10298.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10298.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10299.json
new file mode 100644
index 00000000000..cadab3aff7f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10299.json
@@ -0,0 +1 @@
+{"PONATINIB": 9805.99548923163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/103.json
index d8cb69960b8..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/103.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 19.142103368940788, "CANCIDAS": 36.188647529063, "CLOPIDOGREL": 9.340626889969094, "ELIQUIS": 2.2248903548264574, "LANTUS": 1.9925101067161213, "PEGASYS": 3.138899803904076, "PLAVIX": 3.172403983703888}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1030.json
index 714621034c7..0ac75ae8154 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1030.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1030.json
@@ -1 +1 @@
-{"null": 1.227233003937942}
\ No newline at end of file
+{"ANAKINRA": 211.63000129851383, "ARAVA": 8.73143915907816, "CIMZIA": 14.202457832095291, "COSENTYX": 19.10659964237278, "ENBREL": 14.803946389568535, "HUMIRA": 8.700235070892633, "METHOTREXATE": 14.669640549769095, "null": 0.3189401663583887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10300.json
new file mode 100644
index 00000000000..a00c5ce4e60
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10300.json
@@ -0,0 +1 @@
+{"null": 1.3080303508864288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10301.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10301.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10302.json
new file mode 100644
index 00000000000..f45076cfd04
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10302.json
@@ -0,0 +1 @@
+{"null": 1.3810435918610997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10303.json
new file mode 100644
index 00000000000..300229ae4d9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10303.json
@@ -0,0 +1 @@
+{"MICARDIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10304.json
new file mode 100644
index 00000000000..3060a0eb998
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10304.json
@@ -0,0 +1 @@
+{"ATRIPLA": 1.5055234187276887, "AVANDIA": 3.5803294054449943, "CELECOXIB": 180.81444083313244, "CELLCEPT": 10.267382864777602, "EXFORGE": 8.552600639720499, "ICLUSIG": 64.84892343925344, "MICARDIS": 16.87768020449559, "PLAVIX": 4.384983350925937, "PONATINIB": 587.1133236146788, "RASILEZ": 26.609534044480124, "TASIGNA": 9.94499183112089, "null": 1.2247992076166996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10305.json
new file mode 100644
index 00000000000..75c7f7927e5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10305.json
@@ -0,0 +1 @@
+{"PONATINIB": 3435.407529657426, "null": 0.5861542665449329}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10306.json
new file mode 100644
index 00000000000..6c4b5a68a20
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10306.json
@@ -0,0 +1 @@
+{"LONSURF": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10307.json
new file mode 100644
index 00000000000..4bfc0e37856
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10307.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3850425307836702, "VAXZEVRIA": 0.9563227589282906, "null": 0.6405320364292142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10308.json
new file mode 100644
index 00000000000..595d92a1288
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10308.json
@@ -0,0 +1 @@
+{"ATRIPLA": 7.678270354128946, "TRUVADA": 3.9737051115854354, "null": 0.7668789651908365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10309.json
new file mode 100644
index 00000000000..3e6618c7606
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10309.json
@@ -0,0 +1 @@
+{"AFINITOR": 5.492545130616508, "ATRIPLA": 0.8346567886842627, "BYETTA": 0.5385623543075233, "CABOMETYX": 4.804725309300088, "CELLCEPT": 0.7833293219112992, "CHAMPIX": 0.1799076539224209, "CICLOSPORIN": 0.2882592213294053, "CIMZIA": 0.1941758875006217, "COMIRNATY": 0.0107066418709853, "COSENTYX": 0.3212431684678907, "ELIQUIS": 0.3846654336785051, "ENTRESTO": 0.4990403981777784, "FORXIGA": 0.6392802899081753, "HUMALOG": 1.191042318195067, "INLYTA": 13.607273977950364, "JANUMET": 0.5015262514498023, "JARDIANCE": 0.8259383446302172, "LANTUS": 1.0247402620007895, "LEVEMIR": 0.6278515347449796, "NEXAVAR": 3.4458437632729155, "PAZOPANIB": 3.280296527797834, "RINVOQ": 0.5472140367017715, "SIMPONI": 0.6407494683301643, "STELARA": 1.094994726255866, "SUTENT": 8.196200363992443, "TORISEL": 11.200809613314249, "TRELEGY": 0.850471032940598, "TRULICITY": 0.4644881329780709, "TRUVADA": 0.3141771589977963, "VIAGRA": 0.4163620656274049, "VOTRIENT": 12.652953125544244, "XELJANZ": 0.2665398966797216, "XOLAIR": 0.306956481433364, "ZOSTAVAX": 0.4046557646400497, "null": 6.925040283904693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1031.json
index ba35dedd1f1..472340840a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1031.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1031.json
@@ -1 +1 @@
-{"null": 1.0176359081603588}
\ No newline at end of file
+{"null": 0.8277566403541591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10310.json
new file mode 100644
index 00000000000..7f77d176de5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10310.json
@@ -0,0 +1 @@
+{"AFINITOR": 4.803927229847031, "CABOMETYX": 39.12781870906797, "INLYTA": 32.32716797200273, "NEXAVAR": 4.367835073890012, "SUTENT": 99.11193749236809, "TORISEL": 55.3993001874512, "VOTRIENT": 55.86992310414446, "null": 0.1605714288652617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10311.json
new file mode 100644
index 00000000000..0051cdbc3a7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10311.json
@@ -0,0 +1 @@
+{"VOTRIENT": 67.3760101099884, "null": 0.5419238235720434}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10312.json
new file mode 100644
index 00000000000..90ea7b6a2d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10312.json
@@ -0,0 +1 @@
+{"null": 2.03982116708144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10313.json
new file mode 100644
index 00000000000..ee640751074
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10313.json
@@ -0,0 +1 @@
+{"null": 1.9001059167326195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10314.json
new file mode 100644
index 00000000000..37c8f54500c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10314.json
@@ -0,0 +1 @@
+{"null": 1.7924900272218691}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10315.json
new file mode 100644
index 00000000000..42b2e70c958
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10315.json
@@ -0,0 +1 @@
+{"SUTENT": 61.73362945749711, "VOTRIENT": 28.274708536600084, "null": 0.6096614320622229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10316.json
new file mode 100644
index 00000000000..10cafec00e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10316.json
@@ -0,0 +1 @@
+{"AFINITOR": 9.649330194788348, "ARAVA": 0.0713779628012249, "ATRIPLA": 0.282557644716042, "AXITINIB": 7.94735710109713, "AZATHIOPRINE": 1.5733335450798154, "BYETTA": 0.8217850810673284, "CABOMETYX": 63.29657073028297, "CELLCEPT": 1.1266896763684553, "CICLOSPORIN": 1.4373603166299391, "ELIQUIS": 0.1392258325527932, "EVEROLIMUS": 22.852939290475664, "INLYTA": 24.345961508837025, "NEXAVAR": 27.15587457743393, "PAZOPANIB": 29.374748934370736, "PEGASYS": 0.1355878134527489, "SIMPONI": 0.4136744094070965, "SORAFENIB": 15.910019249109528, "STELARA": 0.7010359225470795, "SUTENT": 136.52478622060704, "TORISEL": 84.2343429833472, "TRUVADA": 0.2731104399888942, "VOTRIENT": 17.74960585889205, "XOLAIR": 0.5145614639032646, "null": 0.2097008901147183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10317.json
new file mode 100644
index 00000000000..0641668b374
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10317.json
@@ -0,0 +1 @@
+{"CABOMETYX": 143.72010923692048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10318.json
new file mode 100644
index 00000000000..a3c87786068
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10318.json
@@ -0,0 +1 @@
+{"SUTENT": 33.897925219235326, "VOTRIENT": 72.01231778799871, "null": 0.6305172096516187}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10319.json
new file mode 100644
index 00000000000..fa29bc67b4b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10319.json
@@ -0,0 +1 @@
+{"ATAZANAVIR": 6.481790813694071, "ATRIPLA": 0.6146469446006081, "BIKTARVY": 8.771942670261758, "COMBIVIR": 8.644779808125227, "COMIRNATY": 0.4673243736700925, "CRIXIVAN": 98.84856729281594, "EXJADE": 2.2673169375475566, "FORSTEO": 5.665711244064321, "FORXIGA": 4.396921057243385, "ISENTRESS": 9.761984086275744, "JARDIANCE": 1.7612928663782754, "KIVEXA": 40.01624325571736, "NORVIR": 126.2362430253976, "PEGASYS": 1.6563825709173907, "REYATAZ": 435.5994258054364, "SAXENDA": 5.149954318320227, "SIMPONI": 1.8636641600243176, "SPIKEVAX": 0.2327588529498678, "TRUVADA": 0.7194113097889114, "VAXZEVRIA": 0.2853574825337047, "XOLAIR": 1.9047613722477224, "null": 0.7733632815407484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1032.json
index ef095318e74..9f1dfa34567 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1032.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1032.json
@@ -1 +1 @@
-{"ABILIFY": 3.0012784991716672, "ACTOS": 2.284566022785265, "ADEFOVIR": 15.445436409911636, "ADENURIC": 3.2755392050165577, "AERIUS": 1.0767166220133484, "APROVEL": 4.43351102993234, "ARIPIPRAZOLE": 3.559795083745246, "AZACITIDINE": 1.126382879450768, "BARACLUDE": 6.307651211340066, "BENZODIAZEPINE": 2.9166141255154985, "BENZODIAZEPINES": 7.491816820058973, "BIKTARVY": 1.738238581689251, "BRAFTOVI": 2.787053910458048, "BRIDION": 1.0298359906770835, "BRILIQUE": 1.1449271690986882, "CABOMETYX": 1.156264323538697, "CARBIDOPA": 2.0663930192786464, "CELLCEPT": 1.0559598549365596, "CELSENTRI": 6.3268085511644445, "CICLOSPORIN": 1.9562514537628248, "COAPROVEL": 1.7064608269719288, "COBIMETINIB": 12.510191807163729, "COMBIVIR": 2.7927875189024887, "COMTAN": 5.882001423050908, "COMTESS": 9.679262533508048, "COTELLIC": 6.72026706243508, "CRIXIVAN": 1.6230326548734846, "CUBICIN": 54.64423165305575, "DABRAFENIB": 5.361261175640397, "DAPTOMYCIN": 7.132789688702759, "DULOXETINE": 1.598600292980215, "EMTRICITABINE": 1.0610687233965133, "EMTRIVA": 3.789295374980386, "ENTACAPONE": 4.588567024552758, "ENTECAVIR": 5.632796378609466, "EPIVIR": 4.994035138708592, "FEBUXOSTAT": 3.293127864291897, "FENTANYL": 1.366097367674761, "GLIVEC": 2.186224402457388, "HARVONI": 1.3994363996743493, "HEPSERA": 2.592709736848435, "HYDROCHLOROTHIAZIDE": 2.109052229109457, "IBUPROFEN": 1.0066443270084282, "INTELENCE": 3.475451418412697, "INVEGA": 4.477519818808439, "INVIRASE": 3.2467921984801187, "INVOKANA": 1.7669139290279074, "IRBESARTAN": 1.154653384572592, "ISENTRESS": 3.477553295064985, "ISOPHANE": 5.515483665600753, "KAFTRIO": 6.204739312870132, "KALETRA": 1.2397216613885271, "KEPPRA": 1.270099120211208, "KEYTRUDA": 1.8170194583861976, "LAMIVUDINE": 1.1730818842424522, "LATUDA": 1.605689132357488, "LEVETIRACETAM": 1.4075759412906188, "LEVODOPA": 2.4012481087550515, "LEVOFLOXACIN": 1.107784902233483, "LYRICA": 1.6568742842302806, "MEKINIST": 6.735145285361813, "METFORMIN": 2.1680684738045417, "MICARDIS": 5.519030324085107, "MIDAZOLAM": 2.304687369559464, "NEXAVAR": 1.1554687241495731, "NILOTINIB": 1.398383599816425, "NORVIR": 2.002202934435132, "OLANZAPINE": 7.899807788702598, "OPDIVO": 2.1419227580911206, "ORKAMBI": 5.952503525734808, "PALIPERIDONE": 5.758346355844452, "PANTOPRAZOLE": 1.884807724355171, "PROTELOS": 3.1172410031194104, "RASILEZ": 2.1304693899691984, "REBETOL": 1.4608175596514872, "REYATAZ": 2.505911739982772, "RINVOQ": 9.48199002843258, "RISPERIDONE": 3.7414610368613226, "RIVAROXABAN": 2.569324450883228, "SEMAGLUTIDE": 5.964969262642309, "SIFROL": 2.2590907344583733, "SOVALDI": 1.8549890209660385, "SPINRAZA": 1.4787587065259746, "STALEVO": 1.7102154998605938, "SYCREST": 4.372535158103086, "TAGRISSO": 2.6123542299220905, "TAMIFLU": 3.2068567682790445, "TELMISARTAN": 3.496464806514477, "TENOFOVIR": 4.284897958206766, "TICAGRELOR": 1.5198851652302003, "TIVICAY": 3.699981670724645, "TRIUMEQ": 1.835229247804263, "UPADACITINIB": 15.949778588386271, "VFEND": 2.763092579095522, "VILDAGLIPTIN": 5.777031937086752, "VIRAMUNE": 2.801894823126513, "VIREAD": 1.9539994697049052, "VORICONAZOLE": 1.044342279110221, "XALKORI": 1.1692019132576696, "YONDELIS": 19.163283829621587, "ZIAGEN": 5.953186378966396, "ZONISAMIDE": 3.452511679802398, "ZYPADHERA": 1.5833725381217023, "ZYPREXA": 9.383103472940888, "null": 2.801613084082044}
\ No newline at end of file
+{"ENBREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10320.json
new file mode 100644
index 00000000000..b90100fdde3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10320.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10321.json
new file mode 100644
index 00000000000..856b17ef7aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10321.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10322.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10322.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10323.json
new file mode 100644
index 00000000000..57a24b12268
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10323.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10324.json
new file mode 100644
index 00000000000..2057f6f84f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10324.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10325.json
new file mode 100644
index 00000000000..ad093562883
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10325.json
@@ -0,0 +1 @@
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diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10326.json
new file mode 100644
index 00000000000..d0fbd4de6f3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10326.json
@@ -0,0 +1 @@
+{"ATAZANAVIR": 67.51693748792914, "KALETRA": 46.49926162897162, "null": 2.9811975919172777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10327.json
new file mode 100644
index 00000000000..92cd1de9878
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10327.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10328.json
new file mode 100644
index 00000000000..d911ccfc79c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10328.json
@@ -0,0 +1 @@
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0.2075148964833788, "SOLIRIS": 1.5281271496093929, "SORAFENIB": 0.5394540679915291, "SOVALDI": 0.6478572991773037, "SPIKEVAX": 0.034735586222164, "SPIRONOLACTONE": 0.6499884834118073, "SPRYCEL": 0.911484686076958, "STALEVO": 0.4187499188948034, "STELARA": 0.3230106584407359, "STIVARGA": 0.322907726943004, "STRIBILD": 16.00421654754964, "SUBOXONE": 0.2620446313238576, "SUNITINIB": 1.1476851184801484, "SUSTIVA": 1.3619115170850462, "SUTENT": 1.1833147934078772, "SYNAGIS": 0.120842503143133, "TACROLIMUS": 0.7597435945496998, "TAGRISSO": 0.3125755105865851, "TAMIFLU": 0.7285433196720796, "TASIGNA": 0.6791995457584804, "TAXOTERE": 0.5188145913382771, "TELMISARTAN": 1.632986808602377, "TENOFOVIR": 3.5900369824311653, "THALIDOMIDE": 1.3150312715237742, "TICAGRELOR": 0.1870201219816026, "TIVICAY": 2.317494151286797, "TOBRAMYCIN": 1.5373140395682745, "TOPOTECAN": 0.6476039856670336, "TORISEL": 3.3586739360783544, "TOUJEO": 0.5825340740566298, "TOVIAZ": 0.3661564766980579, "TOZINAMERAN": 0.0578920593651981, "TRACLEER": 1.3227367625049835, "TRELEGY": 0.3674342543828703, "TREMFYA": 0.1084880115236221, "TRISENOX": 2.459959758845987, "TRIUMEQ": 0.5313355149473005, "TRODELVY": 0.3575493672756232, "TRULICITY": 0.953852699147124, "TRUVADA": 22.710740840214225, "UNSPECIFIED": 0.9521778163213588, "VALSARTAN": 1.186431295844248, "VAXZEVRIA": 0.020615733470965, "VEKLURY": 1.8003829974565455, "VELCADE": 1.4929474757894552, "VELMETIA": 3.589475444829251, "VELTASSA": 2.843566311214428, "VENCLYXTO": 0.9554001469522708, "VENETOCLAX": 0.9324168781303008, "VFEND": 1.6025413961833297, "VIAGRA": 0.4116119982466428, "VICTOZA": 1.739022237113005, "VIMPAT": 0.1887879446562954, "VIRAMUNE": 0.6861474682322397, "VIREAD": 15.05628439390915, "VISTIDE": 4.997215000637539, "VORICONAZOLE": 0.7926993886822062, "VOTRIENT": 0.6718286949042683, "XALKORI": 0.9980959007402916, "XARELTO": 1.0212836609957214, "XELJANZ": 0.3563351172844429, "XELODA": 0.6828525962533055, "XENICAL": 2.9713598274169324, "XOFIGO": 0.3927028491767607, "XOLAIR": 0.1833161843973191, "XTANDI": 0.5128901911358051, "YERVOY": 0.8712798333827432, "YESCARTA": 0.3209486926912369, "YONDELIS": 3.931701952138176, "ZELBORAF": 1.6781807825519326, "ZIAGEN": 0.6835250449078366, "ZOMETA": 0.5755544690711443, "ZOSTAVAX": 0.1860073507931887, "ZYPREXA": 0.7586739596702626, "null": 0.7213395926479207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10329.json
new file mode 100644
index 00000000000..3a288e202fc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10329.json
@@ -0,0 +1 @@
+{"null": 3.4921856886974405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1033.json
index 14f3c4760b2..69b074544e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1033.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1033.json
@@ -1 +1 @@
-{"ATRIPLA": 4.260021302812305, "CELLCEPT": 2.56393174908664, "ELIQUIS": 3.74005847984047, "ENTRESTO": 3.678835301739419, "EXJADE": 5.858515577669999, "FORXIGA": 4.117532216656451, "INCIVO": 5.753007920460614, "JAKAVI": 5.264979656927025, "JANUMET": 2.974079607251851, "JARDIANCE": 1.8845373236955665, "KALETRA": 4.242224377420899, "KEYTRUDA": 3.534098452022449, "SOLIRIS": 15.802140752682744, "STRIBILD": 7.6005497975066785, "SUTENT": 3.4524950848508937, "TRUVADA": 7.110318382294442, "VIREAD": 10.09269997643117, "VOTRIENT": 2.4498793095629003}
\ No newline at end of file
+{"ABACAVIR": 0.4663994828815239, "ABATACEPT": 14.991597381683468, "ACETAMINOPHEN": 17.368259943870395, "ACETYLSALICYLIC": 16.52024151786227, "ADALIMUMAB": 22.016279658851648, "ADVATE": 1.9608579087639808, "AFINITOR": 0.0919948050459286, "AIMOVIG": 1.0117397276438655, "AMINOSALICYLIC": 2.329512758318693, "ANAKINRA": 12.857519718516471, "APIDRA": 0.545512038292013, "APREMILAST": 12.876044526087918, "APREPITANT": 21.884931133281384, "ARAVA": 25.815791582631608, "ATRIPLA": 0.124000346088612, "AUBAGIO": 0.4651776431901515, "AVAMYS": 0.245928300195756, "AZATHIOPRINE": 1.235619226714856, "BELIMUMAB": 5.827965804454518, "BENLYSTA": 0.9403682321389302, "BOSULIF": 0.5218935129826725, "BUDESONIDE": 0.5073341578559728, "BYDUREON": 0.4003586217842408, "BYETTA": 0.8748493353236431, "CABOMETYX": 0.3014072279843752, "CELECOXIB": 1.4892654803906926, "CELLCEPT": 0.1567340672168451, "CHAMPIX": 0.1084205777763462, "CICLOSPORIN": 0.2040320096814014, "CIMZIA": 4.304498566760303, "CLOPIDOGREL": 0.1325993849317727, "COMBIVIR": 0.3781151628198684, "COMIRNATY": 0.0760742051736678, "COSENTYX": 3.758900560676495, "CYMBALTA": 0.4161367599711685, "CYTARABINE": 0.159916687670054, "DEXAMETHASONE": 0.1610885337381551, "DULOXETINE": 1.0019931217296296, "ELIQUIS": 3.321101085097465, "EMPAGLIFLOZIN": 0.918583373061854, "ENBREL": 7.197340132974272, "ENTRESTO": 0.1395500752028565, "ENTYVIO": 0.6984118468425096, "ERELZI": 4.6874100847383655, "ETANERCEPT": 1.5353333373602258, "EVENITY": 0.8166523611620746, "EVISTA": 1.2332770692666686, "EXFORGE": 0.4073059863022005, "EXJADE": 0.1683231884375178, "FAMPYRA": 0.8336055791734199, "FASLODEX": 0.3107096024875299, "FENTANYL": 0.1559389024073119, "FORSTEO": 0.4868026525732326, "GARDASIL": 0.3323346278194899, "GLYCOPYRRONIUM": 1.5815440786454418, "HEMLIBRA": 1.5054037364451742, "HIZENTRA": 0.2548671866033352, "HUMALOG": 0.6681238606745303, "HUMAN": 0.6516220683799157, "HUMIRA": 2.612836024360378, "HYDROCORTISONE": 0.3303469728630324, "IBRANCE": 0.7645218733156693, "IBUPROFEN": 0.3350313675179759, "INLYTA": 0.2248140305261544, "INSULIN": 0.2752634987654602, "IRON": 0.9481895353164888, "JANUMET": 0.3009008222663016, "JANUVIA": 0.301962800175674, "KEYTRUDA": 0.1066522223096407, "LANTUS": 1.1864262831165486, "LEFLUNOMIDE": 2.8960090160883434, "LEVEMIR": 0.2573109298902395, "LEVOFLOXACIN": 0.2596258010448158, "LYRICA": 1.454471586998252, "MEKINIST": 0.1842739313155959, "MELATONIN": 0.9282052908276746, "MEPOLIZUMAB": 0.521025180752957, "METHOTREXATE": 1.764292605170525, "MICARDIS": 0.3867633976048245, "MYCOPHENOLATE": 1.379849968289686, "NUCALA": 0.2039797712569795, "OCEAN": 17.62765613959282, "OFEV": 0.2710147626473297, "OPSUMIT": 0.2016961107533088, "OPTIMARK": 0.2167750228727219, "ORENCIA": 2.3190781281418658, "PEGASYS": 0.1191817413387292, "PEGINTRON": 0.0623431055887575, "PLAVIX": 0.3247289242729498, "RAPAMUNE": 0.8410447855919246, "REMICADE": 1.0865989035707366, "REVATIO": 0.9094966354552584, "REVLIMID": 0.608162235394207, "RINVOQ": 1.688364240274398, "RITUXIMAB": 2.557854891706039, "ROACTEMRA": 0.9808926675403764, "SHINGRIX": 0.1468423332303712, "SIMPONI": 1.4220188359648214, "SKYRIZI": 1.413234128135234, "SPIKEVAX": 0.0397870625722903, "SPRYCEL": 0.7825270564024518, "STELARA": 1.141599936112312, "STRIBILD": 0.0941574065321593, "SUBOXONE": 1.1599161831816365, "SUTENT": 0.3233378409641409, "TASIGNA": 0.2717710021588079, "TOVIAZ": 1.5614990669014193, "TOZINAMERAN": 0.1697754392656152, "TRELEGY": 0.2118840019361346, "TREMFYA": 1.5875338586711607, "TRULICITY": 0.1945899340726326, "TRUVADA": 0.2057736289787594, "TWINRIX": 0.444851412773443, "VAXZEVRIA": 0.0286639993553578, "VFEND": 0.2313754888332374, "VIAGRA": 2.790431530259921, "VICTOZA": 0.263195641366917, "XELJANZ": 3.1560072853776484, "XOLAIR": 0.7104405424052247, "XTANDI": 0.1654741332258248, "ZOMETA": 2.430895632992411, "ZOSTAVAX": 0.8762700399725597, "null": 0.3130256528794502}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10330.json
new file mode 100644
index 00000000000..60412a970ce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10330.json
@@ -0,0 +1 @@
+{"ABACAVIR": 2.818740823808979, "AFINITOR": 2.125634340628813, "AMLODIPINE": 236.61149787421976, "ATRIPLA": 0.9424512610947255, "CAFFEINE": 431.05760751341165, "CICLOSPORIN": 1.1233567064564134, "CLOPIDOGREL": 1.982256880558512, "COMIRNATY": 0.0864715625129032, "CYMBALTA": 0.6402665756659972, "ELIQUIS": 2.258555662301856, "ENTRESTO": 5.806817070336124, "EXJADE": 10.870881320319434, "FORXIGA": 2.89107839537477, "HEPSERA": 23.30656627631284, "IBRANCE": 1.2632154105048052, "JARDIANCE": 2.1643422458353574, "KEYTRUDA": 1.1960177605112812, "LANTUS": 0.5823167435605773, "LEVOFLOXACIN": 32.88684619467331, "LIXIANA": 9.606183613855508, "OPSUMIT": 1.717783010688966, "ROACTEMRA": 2.5913103854349058, "RUBRACA": 28.269337352129163, "STELARA": 1.0811972483128094, "STRIBILD": 1.4087122384686324, "SUTENT": 1.4386985719239662, "TRUVADA": 2.0454385329692077, "VOTRIENT": 1.868823335578717, "XELJANZ": 1.3886395501187658, "null": 0.7166494553397136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10331.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10331.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10332.json
new file mode 100644
index 00000000000..bcaf7489635
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10332.json
@@ -0,0 +1 @@
+{"LEVETIRACETAM": 59.24527710191733, "null": 1.2381422337952954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10333.json
new file mode 100644
index 00000000000..cf416bfbcac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10333.json
@@ -0,0 +1 @@
+{"HEPSERA": 1245.135526670312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10334.json
new file mode 100644
index 00000000000..8b09f6dfb77
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10334.json
@@ -0,0 +1 @@
+{"ELIQUIS": 6.940120959425043, "PLAVIX": 13.70178300273248, "null": 1.821165965575345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10335.json
new file mode 100644
index 00000000000..5d849e919f8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10335.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 6.352348354278576, "COMIRNATY": 0.0597029046977528, "ELIQUIS": 16.13751761965343, "HEMLIBRA": 44.88643496986472, "INLYTA": 12.302893054259268, "LIXIANA": 13.868630299621929, "PLAVIX": 8.940780619981064, "SUTENT": 4.499013754315997, "VOTRIENT": 7.647369860480371, "XARELTO": 49.003750226858166, "null": 0.9025679769777176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10336.json
new file mode 100644
index 00000000000..950d0c7d016
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10336.json
@@ -0,0 +1 @@
+{"null": 0.6786973626991607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10337.json
new file mode 100644
index 00000000000..6ae4cdb7776
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10337.json
@@ -0,0 +1 @@
+{"null": 1.2773650972063433}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10338.json
new file mode 100644
index 00000000000..33a815832f2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10338.json
@@ -0,0 +1 @@
+{"null": 1.0680910332943785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10339.json
new file mode 100644
index 00000000000..944996ba84a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10339.json
@@ -0,0 +1 @@
+{"ABACAVIR": 24.746920393446317, "null": 2.3270705297912806}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1034.json
index 810af19a3b0..91debe3b820 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1034.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1034.json
@@ -1 +1 @@
-{"ABILIFY": 4.443707301634298, "AFINITOR": 2.568708812284544, "AMINOSALICYLIC": 10.297877025771236, "ARIPIPRAZOLE": 3.466555725128508, "BEDAQUILINE": 43.18891062902315, "BEXTRA": 159.54988924297095, "CICLOSPORIN": 1.6561180055881444, "ENBREL": 3.705325774906325, "ENTRESTO": 2.5258460839354218, "EXJADE": 7.373393112307101, "HUMIRA": 5.162526622884266, "IBRANCE": 1.7093689443311733, "JARDIANCE": 2.604213913054723, "KEYTRUDA": 2.8285443080813675, "SOLIRIS": 5.051875513251869, "SUTENT": 1.7272771437795742}
\ No newline at end of file
+{"AMINOSALICYLIC": 12.697509728922162, "BUDESONIDE": 2.547574073810134, "CELECOXIB": 29.73875828067373, "CICLOSPORIN": 5.602985701010941, "CIMZIA": 1.4649011515092794, "COMIRNATY": 0.2926454418295121, "COSENTYX": 2.004346349618986, "CYMBALTA": 1.7700440660731922, "ELIQUIS": 0.8551457969083247, "ENBREL": 3.054132312708799, "GARDASIL": 1.860666574861835, "HUMALOG": 2.278585449235568, "HUMIRA": 2.949295139401982, "IBRANCE": 4.025651508926505, "OMALIZUMAB": 4.197146191587922, "PEGASYS": 0.9324034800582052, "RITUXIMAB": 3.479257796286234, "SIMPONI": 4.812431365779908, "SPIKEVAX": 0.294149447579064, "STELARA": 2.377503199083008, "TOZINAMERAN": 0.8424633137352848, "VAXZEVRIA": 0.06600327100562, "XELJANZ": 4.090575124560802, "ZOSTAVAX": 13.503982961890406, "null": 0.7357053871548328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10340.json
new file mode 100644
index 00000000000..9f97e221baa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10340.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.8618396916810871, "ABATACEPT": 0.1556727146241215, "ABILIFY": 0.6581775650045134, "ABRAXANE": 0.8437252352526099, "ACE": 4.018657817045645, "ACTOS": 1.8258960862138345, "ADALIMUMAB": 0.0450725696122683, "ADCIRCA": 0.9347995586707146, "ADEFOVIR": 7.132376516903422, "ADENURIC": 2.3911841859346668, "AFINITOR": 1.858665753538118, "ALEMTUZUMAB": 1.3765559918328454, "ALIMTA": 3.1511603449487717, "AMIKACIN": 2.0960871129045366, "AMINOSALICYLIC": 1.1369697902257043, "ANAKINRA": 0.2868669704169063, "ANIDULAFUNGIN": 3.5051184866331315, "APIDRA": 0.3383204238894812, "APIXABAN": 0.3460147880635452, "APROVEL": 1.256487183023009, "ARANESP": 1.288917527329421, "ARAVA": 0.219826845202429, "ARIPIPRAZOLE": 0.2189879627880729, "ASPARAGINASE": 0.6193522569732581, "ATAZANAVIR": 0.8150784155816861, "ATRIPLA": 6.5226978716165815, "AUBAGIO": 0.3563658529662578, "AVAMYS": 0.1087304502047937, "AVANDAMET": 0.332863087449789, "AVANDIA": 0.3083551803813622, "AVASTIN": 1.0377677451571736, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10341.json
new file mode 100644
index 00000000000..f0fa6873756
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10341.json
@@ -0,0 +1 @@
+{"null": 3.4980592963929578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10342.json
new file mode 100644
index 00000000000..32f977abd6b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10342.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6784528721024926, "ELIQUIS": 4.132926955508696, "SPIKEVAX": 0.53369951517732, "VAXZEVRIA": 0.8804594162436948, "null": 0.8042904305075085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10343.json
new file mode 100644
index 00000000000..a6a93ba5e6e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10343.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.1072076336028639, "ADEFOVIR": 3.734831100977009, "AMIKACIN": 0.3510259625978608, "AMINOSALICYLIC": 0.1208286594235494, "ATRIPLA": 99.81186483714768, "AVANDIA": 0.2594742231527691, "BIKTARVY": 0.1621123235723011, "BYETTA": 0.526345302835447, "CICLOSPORIN": 0.1423941810351102, "CLOPIDOGREL": 0.0857834493624224, "COMIRNATY": 0.0021692096639593, "DEXAMETHASONE": 0.0571994857129302, "ELIQUIS": 0.0383617374575592, "ENTECAVIR": 1.010925810454812, "ENTRESTO": 0.1839925714510245, "FILGRASTIM": 0.5878969120298525, "FORXIGA": 0.1502336905736003, "GENVOYA": 1.2919026289344742, "HEPSERA": 0.8186396094185922, "HUMALOG": 0.120993118922933, "INVOKANA": 2.2548012230903014, "JARDIANCE": 0.1643130142987132, "KALETRA": 8.144871338373962, "KEYTRUDA": 0.0417754573949319, "LANTUS": 0.0342780273908736, "OPTIMARK": 0.1529640738025801, "PANTOPRAZOLE": 0.5754478896500563, "PAZOPANIB": 0.5663071912099553, "PLAVIX": 0.0496779747404346, "SOLIRIS": 0.0756930312564768, "SPIKEVAX": 0.0045970263917853, "SPIRONOLACTONE": 0.3999469839359845, "STELARA": 0.0561835217873792, "STRIBILD": 25.85561510833812, "SUTENT": 0.0519857807249676, "TENOFOVIR": 1.036809292081216, "TRUVADA": 42.92517582116043, "VAXZEVRIA": 0.0017065122736131, "VIREAD": 16.73859373631145, "null": 0.0392957017796381}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10344.json
new file mode 100644
index 00000000000..57c61d1bca6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10344.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2267079992276429, "MIDAZOLAM": 56.06908197653861, "null": 0.9382339658085088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10345.json
new file mode 100644
index 00000000000..1b9a21c507b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10345.json
@@ -0,0 +1 @@
+{"RYBELSUS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10346.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10346.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10347.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10347.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10348.json
new file mode 100644
index 00000000000..d9592523046
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10348.json
@@ -0,0 +1 @@
+{"AFINITOR": 5.286385652006783, "APIXABAN": 16.573163253191524, "ASPARAGINASE": 11.9801263927708, "ATRIPLA": 5.437123618537491, "AZATHIOPRINE": 34.59385373289434, "CICLOSPORIN": 6.621422592325883, "INLYTA": 8.194431613520164, "JANUVIA": 4.9056993141748535, "LANTUS": 2.236584808133062, "STELARA": 4.032780761220399, "TRUVADA": 1.4458166141523148, "null": 0.5933602828619453}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10349.json
new file mode 100644
index 00000000000..debd3d84d1f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10349.json
@@ -0,0 +1 @@
+{"null": 0.650251090361271}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1035.json
index cc795d139cc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1035.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1035.json
@@ -1 +1 @@
-{"ACLASTA": 1.2393474683102326, "ACTOS": 1.0306943976074685, "ACTRAPID": 1.2363551941247797, "ADCIRCA": 1.5035788617018675, "ADEFOVIR": 12.223504211243814, "ADENURIC": 1.5857892968227554, "ADVAGRAF": 4.2624158150112335, "AFINITOR": 2.77306004088811, "AGENERASE": 8.397804156873724, "ALIMTA": 2.987016799152558, "ALISKIREN": 1.2880797777610982, "ALPELISIB": 2.401949180903367, "AMIKACIN": 1.5569689764644317, "ANTIBIOTICS": 1.260109401778735, "APROVEL": 4.451078524061699, "ATAZANAVIR": 2.095571234344709, "ATEZOLIZUMAB": 1.6824711423095648, "ATRIPLA": 8.230139590679972, "AXITINIB": 1.1236673055867274, "AZATHIOPRINE": 1.5932439801415172, "BARACLUDE": 3.239209824122114, "BASILIXIMAB": 5.074184380603878, "BAVENCIO": 2.1602848864651096, "BEDAQUILINE": 2.749508125605104, "BEVACIZUMAB": 1.31854616712993, "BEXTRA": 2.8211783586784347, "BIKTARVY": 2.550198041659546, "BOSULIF": 1.7447782835911574, "BRAFTOVI": 1.618922389305933, "BRILIQUE": 1.185960604299769, "BUDESONIDE": 1.2270352691558333, "BUMETANIDE": 7.811397544718428, "CAPRELSA": 1.6921878273740862, "CASPOFUNGIN": 1.099119126303243, "CELECOXIB": 6.124796620013664, "CELLCEPT": 4.746346279625621, "CELSENTRI": 2.358429670540305, "CICLOSPORIN": 5.633299543175313, "CIDOFOVIR": 5.193897657878051, "CLOPIDOGREL": 1.009806701476, "COAPROVEL": 3.3341121808779857, "COBIMETINIB": 2.1760195622491394, "COLISTIMETHATE": 4.721646151499575, "COTELLIC": 2.293544211276965, "CRESEMBA": 4.09909814621109, "CRIXIVAN": 5.674368572236696, "CUBICIN": 3.57564811076335, "DAKLINZA": 1.0741916176304545, "DAPAGLIFLOZIN": 1.9644239839660196, "DAPTOMYCIN": 1.6936568938297552, "DARUNAVIR": 1.1167373026692131, "DASATINIB": 1.5415662636102334, "DELAMANID": 4.342163333465987, "DELTYBA": 6.356461844484439, "DESCOVY": 1.8228617769468345, "DOLUTEGRAVIR": 1.4372472112828572, "DOXORUBICIN": 1.0343258863530356, "EBIXA": 1.1163372517864425, "EFAVIRENZ": 1.117135117582333, "EMPAGLIFLOZIN": 2.3925308951798296, "EMTRICITABINE": 2.549051849328, "EMTRIVA": 6.0784234169184375, "ENBREL": 1.0977158799297877, "ENTECAVIR": 7.8563184200077245, "ENTRESTO": 9.478057482141944, "EPCLUSA": 1.034673708925817, "EPIVIR": 2.6522426184794075, "ESOMEPRAZOLE": 1.090161896708927, "EUCREAS": 1.501268845573629, "EVEROLIMUS": 1.6829982775349297, "EXFORGE": 2.7584972517523774, "EXJADE": 10.89301595912391, "FEBUXOSTAT": 2.9787129082923007, "FORXIGA": 3.71974371891938, "FULVESTRANT": 1.331542246086451, "GALVUS": 1.2583151488479745, "GANCICLOVIR": 1.3292652987882476, "GENVOYA": 5.129126880869724, "GLIVEC": 2.113209105200056, "HARVONI": 2.042799798905388, "HEPSERA": 8.54923707554949, "HYDROCHLOROTHIAZIDE": 4.936031143424768, "IBUPROFEN": 1.4602351537431075, "INCIVO": 3.3260236428981806, "INLYTA": 1.7027223282346655, "INTEGRILIN": 2.3902030808793446, "INVIRASE": 1.572176802085428, "INVOKANA": 1.1703683947557342, "IRBESARTAN": 1.91251832950249, "ISENTRESS": 1.3770022104765856, "ISOPHANE": 3.748518540921511, "JAKAVI": 1.3291726543103315, "JANUMET": 1.0515184499088814, "JARDIANCE": 1.918313402103912, "KALETRA": 2.280655492006956, "KEYTRUDA": 1.1769607189927285, "KISQALI": 2.1884418505127563, "KIVEXA": 2.252735372748044, "KYPROLIS": 2.000381789456292, "LAMIVUDINE": 1.2663964235508414, "LENVIMA": 1.1218762091106147, "LEVOFLOXACIN": 1.055046270155952, "LIRAGLUTIDE": 1.338198594178277, "LOPINAVIR": 1.5406948922165289, "LUPKYNIS": 11.126481027574018, "LYNPARZA": 2.732543476246841, "MELPHALAN": 1.075896073138613, "MEMANTINE": 1.3173791786392963, "MERCAPTOPURINE": 1.320228682619271, "MICARDIS": 4.062612593620676, "MICARDISPLUS": 1.8709333505951145, "MIMPARA": 1.031506084420443, "MULTAQ": 10.203298766751136, "MYCOPHENOLATE": 3.06481573361942, "NEVIRAPINE": 1.1395945249436863, "NEXAVAR": 1.1935468796448572, "NORVIR": 2.241142161003636, "NOT": 1.0465452081238102, "NOXAFIL": 1.005461362490039, "NUBEQA": 1.957960868720116, "OLAPARIB": 1.4172474933511603, "OLYSIO": 1.689862075480195, "ONGLYZA": 1.2818939206115956, "PAZOPANIB": 1.3680743245611502, "PEGINTERFERON": 2.1289510188418657, "PEMETREXED": 2.65723815982791, "PONATINIB": 10.010033682439452, "POSACONAZOLE": 1.830696162612718, "PROTELOS": 1.866364849156843, "RANEXA": 2.1424472983394653, "RANOLAZINE": 2.227887020088801, "RAPAMUNE": 4.45681864788023, "RASILEZ": 11.644014727329289, "REMDESIVIR": 9.449955324404542, "REYATAZ": 4.057703972461057, "RIBOCICLIB": 2.0874397691908726, "RIVAROXABAN": 1.513884796809016, "RUBRACA": 7.525438598676626, "RUXOLITINIB": 1.4149832644658882, "SAMSCA": 7.059129899999058, "SIMEPREVIR": 3.510474653105271, "SIMULECT": 10.554728842142492, "SOLIRIS": 4.373496698708891, "SPIRONOLACTONE": 4.861131845862096, "STRIBILD": 6.959423137482869, "SUNITINIB": 1.6668211042574266, "SUTENT": 2.315404100599315, "TACROLIMUS": 3.813735773258565, "TASIGNA": 1.1203254038652493, "TEKTURNA": 9.11414697954562, "TELAPREVIR": 20.323346852892215, "TELMISARTAN": 2.3743380964573357, "TENOFOVIR": 9.830290059793509, "THALIDOMIDE": 1.5093616226526925, "TIVICAY": 4.0523572205468845, "TOBRAMYCIN": 6.760496047570615, "TOCOPHEROL": 6.501998249629692, "TORISEL": 7.317667885973548, "TRIUMEQ": 2.5162463048154478, "TRUVADA": 7.88866961075191, "VALSARTAN": 7.221032473508703, "VEKLURY": 1.9088633576534744, "VENETOCLAX": 1.4285019883628898, "VFEND": 1.2485443858853078, "VIREAD": 10.32024122744794, "VISTIDE": 13.879377033623626, "VORICONAZOLE": 1.7323004526934027, "VOTRIENT": 1.2909341659538318, "XALKORI": 1.29222678549206, "YONDELIS": 1.6198339760405127, "ZELBORAF": 1.5819114262629963, "ZIAGEN": 2.7379568590437056, "ZOMETA": 5.489353047981829, "null": 1.1659692091017548}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10350.json
new file mode 100644
index 00000000000..929377b779c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10350.json
@@ -0,0 +1 @@
+{"ATRIPLA": 1.6736923420823449, "COMIRNATY": 0.0653686236574705, "LANTUS": 2.0469751060077703, "OMALIZUMAB": 13.809862839549446, "STELARA": 4.589965377935189, "SUTENT": 1.3432790321832164, "VOTRIENT": 10.66152154585468, "null": 0.8025083716312735}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10351.json
new file mode 100644
index 00000000000..fb5a17f0407
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10351.json
@@ -0,0 +1 @@
+{"null": 1.1637784968729086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10352.json
new file mode 100644
index 00000000000..3fa1b5f0962
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10352.json
@@ -0,0 +1 @@
+{"AIMOVIG": 0.5221878002588132, "ATRIPLA": 1.1268282498742408, "AUBAGIO": 0.4578774326901065, "AZATHIOPRINE": 1.3858270341337144, "BENLYSTA": 2.015184507114773, "BIKTARVY": 1.1528845805335977, "BYDUREON": 1.959038181396262, "CHAMPIX": 1.7124206032208669, "CLOPIDOGREL": 0.2845605841439269, "COMIRNATY": 1.46059349646462, "CRIXIVAN": 13.240787367702504, "CYMBALTA": 0.3255797223124296, "ELIQUIS": 0.2236063781772482, "ENTRESTO": 0.7763309563554891, "EXFORGE": 1.235407096635163, "EXJADE": 0.6842542794411354, "FASENRA": 0.8911208470844, "FORSTEO": 3.127244615048202, "FORXIGA": 2.677960035299016, "GARDASIL": 0.3013512819483936, "HIZENTRA": 0.9147042112087264, "HUMALOG": 0.2374858368218435, "JANUVIA": 0.4888983434702271, "JARDIANCE": 2.7924191633344835, "LANTUS": 0.3974952686396942, "LEVOFLOXACIN": 0.757395724356179, "MODERNA": 0.826269374896904, "OCRELIZUMAB": 2.877842697758765, "OLANZAPINE": 0.3638787566171244, "PEGASYS": 1.0216862880730633, "PEGINTRON": 0.2533328103011507, "PLAVIX": 0.4054420805929637, "PRIVIGEN": 1.1515211935751914, "REYATAZ": 3.8921833196092233, "RINVOQ": 0.7354276044045417, "SAXENDA": 0.7947931954670773, "SHINGRIX": 0.32746917339583, "SIMPONI": 0.606879851269634, "SOLIRIS": 0.5382995279300491, "SPIKEVAX": 1.7626377470276695, "STELARA": 0.5497986641945212, "STRIBILD": 1.4255560022005265, "SUBOXONE": 0.4279035465159004, "SUTENT": 0.6523002204474329, "TOVIAZ": 1.1295182672534247, "TOZINAMERAN": 1.7369485954044876, "TRUVADA": 1.2759892366663232, "VAXZEVRIA": 2.825816310675893, "XELJANZ": 0.797154697461421, "XTANDI": 0.3875499732735205, "ZOSTAVAX": 0.361837145894517, "null": 0.5428569856855365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10353.json
new file mode 100644
index 00000000000..289b1ceca00
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10353.json
@@ -0,0 +1 @@
+{"null": 1.068453339061557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10354.json
new file mode 100644
index 00000000000..289b1ceca00
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10354.json
@@ -0,0 +1 @@
+{"null": 1.068453339061557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10355.json
new file mode 100644
index 00000000000..0ac41087ca8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10355.json
@@ -0,0 +1 @@
+{"null": 1.1384427691239858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10356.json
new file mode 100644
index 00000000000..a90abaea230
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10356.json
@@ -0,0 +1 @@
+{"VOTRIENT": 65.51764541373763, "null": 0.7117380530925279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10357.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10357.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10358.json
new file mode 100644
index 00000000000..9e612129650
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10358.json
@@ -0,0 +1 @@
+{"APIDRA": 4.629901401500473, "ARANESP": 44.59099995659517, "ATRIPLA": 4.142540604227387, "CICLOSPORIN": 4.446970304258014, "CYMBALTA": 1.0614043120490813, "HUMALOG": 4.122826716448303, "LANTUS": 19.756297126474763, "LEVEMIR": 7.962074110426474, "MIMPARA": 47.82512990416674, "SOLIRIS": 18.430307852359977, "TRUVADA": 5.06634876579056, "VELTASSA": 58.12345243109648, "VIREAD": 11.51444411457478, "ZOSTAVAX": 1.781027673292395, "null": 0.7163953911685962}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10359.json
new file mode 100644
index 00000000000..6b3b30a7b5e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10359.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 31.61018801777916, "CELLCEPT": 29.00662466095116, "CICLOSPORIN": 87.16684546691214, "MYCOPHENOLATE": 134.16107115004408, "SOLIRIS": 46.27658008751978, "null": 0.2620024696275372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1036.json
index 8b1279a323f..42666b6d569 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1036.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1036.json
@@ -1 +1 @@
-{"SPIKEVAX": 35.01662930204063}
\ No newline at end of file
+{"COMIRNATY": 0.4894093506379953, "SPIKEVAX": 0.6161644750038097, "VAXZEVRIA": 0.4960251361861235, "null": 0.6776605754656471}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10360.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10360.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10361.json
new file mode 100644
index 00000000000..0c20c9b90b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10361.json
@@ -0,0 +1 @@
+{"ATRIPLA": 4.802352385306294, "EMTRICITABINE": 28.0202350520218, "EXJADE": 14.132654913896944, "HEPSERA": 57.90662626641055, "IBUPROFEN": 9.5684513474475, "JARDIANCE": 2.040667833458631, "KALETRA": 15.663358772859036, "KEYTRUDA": 2.5977353359869477, "LEVETIRACETAM": 6.02518641997147, "LOPINAVIR": 43.550412656620615, "NORVIR": 32.84003602602806, "SPINRAZA": 16.411660718642572, "TENOFOVIR": 160.38798791436352, "TRUVADA": 5.421255522672472, "VIREAD": 48.93393444774176, "null": 1.067297757102358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10362.json
new file mode 100644
index 00000000000..e238061a243
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10362.json
@@ -0,0 +1 @@
+{"CELLCEPT": 12.50718494812206, "CICLOSPORIN": 46.24240803702973, "MYCOPHENOLATE": 30.744578105931502, "TRUVADA": 2.142987850356737, "null": 1.271973079336215}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10363.json
new file mode 100644
index 00000000000..8b03124a57a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10363.json
@@ -0,0 +1 @@
+{"ATAZANAVIR": 5.915773150942504, "ATRIPLA": 2.6997633626583184, "BASILIXIMAB": 15.117970114902938, "CELLCEPT": 5.984436146997695, "CICLOSPORIN": 2.234630039444764, "DOLUTEGRAVIR": 22.02158730724053, "EMTRICITABINE": 12.369877000471435, "EXJADE": 11.188366386069177, "HEPSERA": 98.07129314915124, "INTELENCE": 36.19940474362985, "ISENTRESS": 10.850847695665406, "KALETRA": 10.350931277314428, "KEYTRUDA": 0.8796744976531538, "NORVIR": 79.18725397218712, "PANITUMUMAB": 35.64491850837888, "STRIBILD": 5.482068065821315, "TENOFOVIR": 435.4851892212097, "TRUVADA": 13.40839534215308, "VIREAD": 58.145386047958354, "null": 0.8333021835686611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10364.json
new file mode 100644
index 00000000000..8962fcc8839
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10364.json
@@ -0,0 +1 @@
+{"ABACAVIR": 4.546955439109031, "ATAZANAVIR": 18.06212367267128, "ATRIPLA": 6.675297066340862, "EMTRICITABINE": 57.13217686600649, "EXJADE": 5.08523625607752, "HEPSERA": 103.9915162946266, "STRIBILD": 5.2914957233283, "TENOFOVIR": 371.5404758912924, "TRUVADA": 17.296448026875595, "VIREAD": 178.77414151084986, "null": 0.5666520968275669}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10365.json
new file mode 100644
index 00000000000..36ecaa28455
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10365.json
@@ -0,0 +1 @@
+{"ATRIPLA": 13.385585876153572, "BUSULFAN": 49.368869753501215, "CICLOSPORIN": 11.51957130152732, "TRUVADA": 5.101837965715749, "null": 0.6395239542711297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10366.json
new file mode 100644
index 00000000000..91a671d8db1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10366.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.1625340239041704, "AFINITOR": 0.9247278537736974, "ALIMTA": 4.194583772143596, "AMIKACIN": 3.884189364934071, "APROVEL": 5.4774667936326, "ASPARAGINASE": 2.8616712700174745, "ATAZANAVIR": 7.595659462682406, "ATRIPLA": 3.3588408399980456, "AVASTIN": 1.5140717145473912, "BASILIXIMAB": 27.10429770032339, "BYETTA": 2.024606950689963, "CELLCEPT": 4.137641942556373, "CELSENTRI": 24.838953255165272, "CICLOSPORIN": 3.864394772508887, "CLOPIDOGREL": 0.4480550307542164, "COMIRNATY": 0.0100917393108974, "CUBICIN": 3.827711585342008, "EFAVIRENZ": 3.957310258464496, "EMTRICITABINE": 10.414453272042175, "ENBREL": 0.9050800265271278, "ENTRESTO": 1.2351698576095835, "EPIVIR": 8.437768423092422, "EXJADE": 3.0605772355299328, "FEBUXOSTAT": 12.729132856234658, "IBUPROFEN": 4.582575040064681, "INVOKANA": 6.47294286560612, "IRBESARTAN": 8.814977681348017, "JARDIANCE": 0.7546759590154847, "KALETRA": 8.266553250087705, "KEYTRUDA": 1.2261583178649331, "LOPINAVIR": 11.673616049739843, "METHOTREXATE": 1.4761548492679333, "MICARDIS": 2.112114062594691, "MYCOPHENOLATE": 7.743604056053625, "NORVIR": 6.1356269078419645, "PEGASYS": 0.8969838103214874, "PEGINTERFERON": 1.8501503701571065, "PEMBROLIZUMAB": 8.047633531453819, "PEMETREXED": 13.187362614981147, "RAPAMUNE": 6.25641670946037, "REYATAZ": 7.764222364023111, "SOLIRIS": 2.4203481696228786, "STRIBILD": 2.957742685840929, "TACROLIMUS": 6.980908071945522, "TENOFOVIR": 22.580582914456304, "TOBRAMYCIN": 76.80143955603143, "TRUVADA": 4.684604416254127, "VIREAD": 23.450904354446305, "null": 1.5565360250530995}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10367.json
new file mode 100644
index 00000000000..b875c0411fd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10367.json
@@ -0,0 +1 @@
+{"null": 0.5063454530123213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10368.json
new file mode 100644
index 00000000000..620c00d6e04
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10368.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3622448246081002, "null": 0.6795978015750531}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10369.json
new file mode 100644
index 00000000000..326a00da659
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10369.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3887102753095121, "SUTENT": 3.407507734319413, "VAXZEVRIA": 1.3866470198709129, "null": 0.3970339065048533}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1037.json
index af1bdc8a3f2..1f8ec2c6826 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1037.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1037.json
@@ -1 +1 @@
-{"SPIKEVAX": 11.423906227210628}
\ No newline at end of file
+{"null": 0.8441661466746129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10370.json
new file mode 100644
index 00000000000..5db20dc5145
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10370.json
@@ -0,0 +1 @@
+{"null": 2.846137987720282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10371.json
new file mode 100644
index 00000000000..6d51e116733
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10371.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 54.88882740040719, "null": 0.8420635730178451}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10372.json
new file mode 100644
index 00000000000..8679cb18d1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10372.json
@@ -0,0 +1 @@
+{"ENTRESTO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10373.json
new file mode 100644
index 00000000000..dc495472cab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10373.json
@@ -0,0 +1 @@
+{"null": 2.30259427927768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10374.json
new file mode 100644
index 00000000000..96a7b8341ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10374.json
@@ -0,0 +1 @@
+{"RASILEZ": 277.7919181710361, "null": 2.080820559517006}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10375.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10375.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10376.json
new file mode 100644
index 00000000000..a24fc24e095
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10376.json
@@ -0,0 +1 @@
+{"null": 1.2565735543080117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10377.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10377.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10378.json
new file mode 100644
index 00000000000..a37f242f7f1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10378.json
@@ -0,0 +1 @@
+{"ANGIOX": 2923.133191845433, "null": 0.5450858387780103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10379.json
new file mode 100644
index 00000000000..b89a77509e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10379.json
@@ -0,0 +1 @@
+{"null": 3.140006312087862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1038.json
index 156bbdea239..46afd973877 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1038.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1038.json
@@ -1 +1 @@
-{"OPSUMIT": 79.30190455036674, "SPIKEVAX": 2.650084345537598}
\ No newline at end of file
+{"JANUMET": 18.61263505834481, "ZOSTAVAX": 11.368611215740655, "null": 1.332940354102636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10380.json
new file mode 100644
index 00000000000..cb4c8ceb16c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10380.json
@@ -0,0 +1 @@
+{"OCEAN": 10922.780900207154}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10381.json
new file mode 100644
index 00000000000..7b5e68536c4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10381.json
@@ -0,0 +1 @@
+{"EPCLUSA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10382.json
new file mode 100644
index 00000000000..311ac39002a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10382.json
@@ -0,0 +1 @@
+{"null": 1.796628255485857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10383.json
new file mode 100644
index 00000000000..4c076974747
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10383.json
@@ -0,0 +1 @@
+{"null": 3.440318901667623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10384.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10384.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10385.json
new file mode 100644
index 00000000000..569137efd5f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10385.json
@@ -0,0 +1 @@
+{"TOVIAZ": 467.9031164856961, "null": 2.054152875503416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10386.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10386.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10387.json
new file mode 100644
index 00000000000..15ca6d41d09
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10387.json
@@ -0,0 +1 @@
+{"CELECOXIB": 313.39479916085634, "DEXAMETHASONE": 30.33998188847294, "null": 0.3526035643047444}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10388.json
new file mode 100644
index 00000000000..f6338f44c88
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10388.json
@@ -0,0 +1 @@
+{"CIMZIA": 1.8954560496447592, "CLOPIDOGREL": 0.5496821857979579, "COMIRNATY": 1.1863802495939686, "CYMBALTA": 0.661639577413288, "ELIQUIS": 0.9572825721894074, "ESBRIET": 1.7741890231274182, "FENTANYL": 1.67626396882656, "HARVONI": 3.522637375767661, "INSULIN": 15.384672251217475, "JARDIANCE": 0.600174140667151, "KEYTRUDA": 0.3678824546534387, "LEVOFLOXACIN": 0.7257598055922762, "MEPOLIZUMAB": 5.8901757780222646, "MIDAZOLAM": 4.332763125685568, "MMRVAXPRO": 4.477757732942134, "NUCALA": 3.4636639907880054, "OLANZAPINE": 1.584448590312513, "OMALIZUMAB": 2.9660082018884024, "OPSUMIT": 2.0067228312096104, "ORKAMBI": 45.7458022871807, "SPIKEVAX": 0.7125825640529305, "SYNAGIS": 4.112746645026419, "TOZINAMERAN": 1.0036327425896254, "TRELEGY": 2.2661315987433364, "VAXZEVRIA": 1.0041990034213737, "XELJANZ": 0.5529872509660744, "ZOSTAVAX": 1.0166838211853169, "null": 1.1069108899459306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10389.json
new file mode 100644
index 00000000000..00b009b681a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10389.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 4.604598589189398, "BUDESONIDE": 1.7816285275391857, "BUPIVACAINE": 7.120707709980858, "BUPRENORPHINE": 3.092783595545366, "CICLOSPORIN": 0.9154882832870468, "COMIRNATY": 0.0558065061605913, "DEXAMETHASONE": 3.051617448480653, "ELIQUIS": 0.5283055950099175, "FENTANYL": 18.08010571177577, "GLIBENCLAMIDE": 22.66230604191093, "HYDROCORTISONE": 7.050838417565642, "IBUPROFEN": 4.929587209630282, "JARDIANCE": 4.166758531801063, "KEPPRA": 2.016555852265231, "LACOSAMIDE": 7.003539522978501, "LEVOFLOXACIN": 1.8344612266365043, "MIDAZOLAM": 12.830893590626342, "OLANZAPINE": 3.5409656295284937, "ZYPREXA": 1.7807454920225034, "null": 3.11661346326793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1039.json
index 8d56f6963d9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1039.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1039.json
@@ -1 +1 @@
-{"ASPARAGINASE": 13.16169259847029, "BUSILVEX": 103.77352728849492, "BUSULFAN": 27.83480096752594, "CASPOFUNGIN": 62.59636559945123, "CICLOSPORIN": 2.656992934445338, "CYTARABINE": 20.62004837738728, "EPIVIR": 26.825761801253947, "EXJADE": 5.538900191804967, "OPSUMIT": 17.568811855734396, "TRACLEER": 19.469518111938108, "null": 1.1161172797462455}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10390.json
new file mode 100644
index 00000000000..7a46073476a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10390.json
@@ -0,0 +1 @@
+{"ACTRAPID": 90.13850669911108, "COMIRNATY": 0.1801861090458385, "NALOXONE": 399.3790692786419, "null": 2.216074212144823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10391.json
new file mode 100644
index 00000000000..e69146bd5a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10391.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10392.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10392.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10393.json
new file mode 100644
index 00000000000..c87625f1929
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10393.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 8.266064383478582, "BENZODIAZEPINE": 8.277436106554003, "BRIDION": 6.5374224362745945, "BUCCOLAM": 166.99216145940065, "BUDESONIDE": 0.2683574300205593, "BUPIVACAINE": 15.270348013377712, "BUPRENORPHINE": 14.340294111879576, "BUVIDAL": 12.637224958243204, "COMIRNATY": 0.0221744845620982, "CYMBALTA": 1.1399142000044291, "DEXMEDETOMIDINE": 28.73982369144186, "DULOXETINE": 5.308398001884131, "FENTANYL": 25.49779144819928, "GLUCAGON": 17.646401564870867, "HUMIRA": 0.6740980267985691, "HYDROCORTISONE": 1.6374820727132169, "IBUPROFEN": 1.9801165375554377, "KEPPRA": 1.1017501513122758, "LEVETIRACETAM": 0.7884761594137074, "LYRICA": 3.503742198403054, "MIDAZOLAM": 30.64796143763205, "NALOXONE": 18.967529158242627, "OLANZAPINE": 4.4541621120866735, "PEGASYS": 0.1196935388812608, "PREGABALIN": 12.98200079121052, "RISPERIDONE": 37.90971896698693, "SPIKEVAX": 0.0137246474463784, "SUBOXONE": 6.121845755922591, "SUFENTANIL": 21.54729923188729, "VFEND": 0.6113243086573852, "XYREM": 8.265027129324123, "ZALVISO": 255.73332124954285, "ZYPREXA": 3.803655832250898, "null": 4.565055469770228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10394.json
new file mode 100644
index 00000000000..4dfa958879e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10394.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5676311169672802, "SPIKEVAX": 1.6807471667483376, "VAXZEVRIA": 0.9652589920728752, "null": 0.5626422200777647}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10395.json
new file mode 100644
index 00000000000..030666f2ec4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10395.json
@@ -0,0 +1 @@
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10396.json
new file mode 100644
index 00000000000..b22d9a9726c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10396.json
@@ -0,0 +1 @@
+{"ABATACEPT": 5.853704660088353, "ACLIDINIUM": 13.193316309498613, "ADALIMUMAB": 0.2147095752906883, "AFINITOR": 0.7940471237089971, "AIMOVIG": 0.3801774899445583, "ALEMTUZUMAB": 3.0986990965992365, "AMINOSALICYLIC": 1.2595671197346046, "ANORO": 3.073818100741375, "ARAVA": 6.309059389354301, "ARIPIPRAZOLE": 0.3938623325141798, "ASPARAGINASE": 1.3746166076315294, "AUBAGIO": 0.3838969433962302, "AVAMYS": 1.378966146967309, "AVANDIA": 0.5668770088159453, "BENLYSTA": 1.879719468877224, "BRAFTOVI": 0.757294510512043, "BRIDION": 2.1228158710547325, "BRILIQUE": 0.6739618739329625, "BUDESONIDE": 0.9277954909948236, "BUPRENORPHINE": 0.5290512205655928, "BUSULFAN": 2.182677422179451, "CELLCEPT": 0.6108310329471284, "CHAMPIX": 0.4681030635756369, "CHLORHEXIDINE": 1.4893496646737887, "CICLOSPORIN": 1.224290145989818, "CIMZIA": 1.6586914527041017, "CLOPIDOGREL": 0.4348455100109608, "COMBIVIR": 1.8176472749533477, "COMIRNATY": 0.4896400714990785, "COSENTYX": 0.5690277234367677, "CYMBALTA": 0.1521962501189444, "CYTARABINE": 0.8047711827457666, "DARZALEX": 2.398370254602616, "DEXAMETHASONE": 0.7961699971621009, "DUAKLIR": 37.45509240286375, "ELIQUIS": 0.6073829353854433, "ENBREL": 0.3045595656751368, "ENTRESTO": 0.5438599590644908, "ERENUMAB": 6.717266146899371, "ESBRIET": 3.011688579061909, "ESOMEPRAZOLE": 0.9678561615548644, "EXFORGE": 0.6348419501062429, "EXJADE": 0.4981702187989221, "FASENRA": 2.1432737176251244, "FASLODEX": 0.6290285652186545, "FENTANYL": 1.5973856061634957, "FORSTEO": 1.5174550816691152, "GARDASIL": 0.3469021943047004, "GLYCOPYRRONIUM": 4.817130224566473, "HARVONI": 0.6507317653976312, "HIZENTRA": 1.6863100262997135, "HUMALOG": 0.177962831417824, "HUMIRA": 0.4142124372443402, "HYDROCORTISONE": 3.568656818210146, "IBRANCE": 0.8540155448105996, "IBUPROFEN": 1.025598284913294, "INSULIN": 0.784219535460025, "JANUMET": 1.0194205847225997, "JANUVIA": 0.5993886251192939, "JARDIANCE": 0.2752894661702643, "KAFTRIO": 0.8896529586103561, "KALETRA": 1.5751020910533444, "KEPPRA": 0.5960178984285756, "KEYTRUDA": 0.3454203444024628, "KYMRIAH": 1.3881511244244624, "LANTUS": 0.8900914068460525, "LEVOFLOXACIN": 0.6191344900520548, "LYRICA": 0.4686499654821653, "MEPOLIZUMAB": 4.636085107492743, "METHOTREXATE": 0.9758905844024552, "MIDAZOLAM": 2.538642061891472, "MULTAQ": 1.1710178924557386, "NAGLAZYME": 10.744914177809369, "NEULASTA": 0.7724646561959341, "NEXAVAR": 0.5537609903571185, "NOT": 1.1383463640027922, "NUCALA": 2.868820589208949, "OFEV": 2.173575047090299, "OLANZAPINE": 0.663594538450637, "OMALIZUMAB": 3.536288290223366, "OPSUMIT": 1.8015761974636584, "ORKAMBI": 3.1851075493451675, "PEGASYS": 0.3789118606936157, "PEGINTERFERON": 1.0160456071946615, "PEGINTRON": 1.25464018506442, "PEMBROLIZUMAB": 0.717296233011378, "PLAVIX": 0.7054831273242829, "PRIVIGEN": 0.6262995319982151, "RELVAR": 3.513107506681759, "REMDESIVIR": 5.038094676562073, "REVATIO": 1.65943285335186, "RITUXIMAB": 0.4411167322439779, "SIMPONI": 1.4244664316944062, "SOLIRIS": 0.4513256707855383, "SPIKEVAX": 0.2280981341314095, "SPINRAZA": 19.68683494139902, "SPRYCEL": 0.881948266109031, "STELARA": 0.5074216621435812, "SUBOXONE": 0.2948248560833837, "SUTENT": 0.5148404000885005, "SYNAGIS": 10.79803298265356, "TAMIFLU": 0.4883141091262732, "TOBRAMYCIN": 5.513658245695871, "TOZINAMERAN": 0.515538929289962, "TRACLEER": 1.4455776955762214, "TRELEGY": 2.1565536742881704, "TREMFYA": 1.1904680634166012, "VAXZEVRIA": 0.4060648908524518, "VEKLURY": 6.422839772711661, "VFEND": 0.6847815319703134, "VOTRIENT": 0.503234161028948, "XALKORI": 0.9045237945376444, "XELJANZ": 1.1613049861391256, "XOLAIR": 3.409257585453896, "XTANDI": 0.475133577762336, "ZOSTAVAX": 0.6200345494953332, "ZYPREXA": 0.4976625137892859, "null": 1.1784396438072826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10397.json
new file mode 100644
index 00000000000..851fc3a9812
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10397.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 14.336940713770767, "CYMBALTA": 4.110527010473364, "LEVEMIR": 29.518148860235986, "SUBOXONE": 10.604332462773012, "ZYPREXA": 4.234480986408012, "null": 2.586880359946778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10398.json
new file mode 100644
index 00000000000..ee142b2d8aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10398.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.256615927407433, "ACTRAPID": 1.863750858098035, "ADCIRCA": 2.0510171629656075, "AERIUS": 2.2905075644742032, "AFINITOR": 0.7493266928496651, "AIMOVIG": 0.1493141618225993, "ALEMTUZUMAB": 1.1677378561813885, "ALIMTA": 1.319447098723156, "AMIKACIN": 3.08836736286121, "AMINOSALICYLIC": 1.0513861482991125, "APIDRA": 0.6256788747370825, "ARANESP": 0.3842209391715431, "ARAVA": 0.0687547618452809, "ARIPIPRAZOLE": 0.3123045860988249, "ASPARAGINASE": 1.981973618736516, "ATOSIBAN": 9.197036250336888, "AVAMYS": 1.3225091454054436, "AVANDIA": 0.4464822115393219, "AZACITIDINE": 2.457462934831252, "BEDAQUILINE": 4.531881974107412, "BRIDION": 1.056077966931981, "BRILIQUE": 0.4824369612227703, "BUDESONIDE": 0.9868118704362542, "BUPIVACAINE": 0.7287832893281517, "BUPRENORPHINE": 0.4749898079870858, "BUSULFAN": 2.2382076058041607, "CAELYX": 1.467254827058798, "CANCIDAS": 2.1981751754294296, "CASPOFUNGIN": 2.833815884556932, "CELECOXIB": 1.5647380064713807, "CELLCEPT": 0.5725122104896988, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10399.json
new file mode 100644
index 00000000000..d4d9b0a5481
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10399.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.2469587765933037, "ABILIFY": 0.8394896025259034, "ACTRAPID": 24.603194314622364, "ADALIMUMAB": 0.0184135692339256, "ADCIRCA": 2.3918983790054686, "ADEMPAS": 2.543170700643128, "AFINITOR": 1.4989336753673514, "ALEMTUZUMAB": 3.9103554922225823, "ALENDRONIC": 27.315720864440745, "ALIMTA": 2.7729638301706743, "AMIKACIN": 3.2289665668490297, "AMINOSALICYLIC": 7.278916083457141, "ANGIOX": 4.717831041274878, "ANIDULAFUNGIN": 4.206302224861135, "ANTIBIOTICS": 2.8123856319576745, "APIXABAN": 0.5699336925393858, "APREPITANT": 1.654319947865675, "ARANESP": 0.1859755534738123, "ARAVA": 0.1571887235050651, "ARIPIPRAZOLE": 0.5148223271381934, "ASPARAGINASE": 1.825634670869833, "ATAZANAVIR": 0.4843155219025635, "ATRIPLA": 0.0222607571991478, "AUBAGIO": 0.1849338143891355, "AVANDAMET": 1.7556707377609924, "AVANDIA": 3.0817669396131757, "AVASTIN": 1.1985223594697445, "AXITINIB": 1.1125806285133124, "AZACITIDINE": 2.8077252696461543, "AZATHIOPRINE": 0.7720231392581299, "BASILIXIMAB": 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2.269743185292916, "ENTRESTO": 0.7061305771697549, "ENTYVIO": 0.3369931963767001, "EPCLUSA": 0.8572609350103733, "EPIVIR": 0.7407286071670104, "ERBITUX": 1.1093390501738092, "ESBRIET": 4.337873811246519, "ESOMEPRAZOLE": 2.267260404584704, "EVEROLIMUS": 2.4105774657978736, "EVISTA": 0.3959206333274944, "EXFORGE": 0.7491147544550517, "EXJADE": 1.9125166355574967, "FASENRA": 1.7494603772828614, "FASLODEX": 0.8083187333050418, "FASTURTEC": 5.107167888920843, "FEBUXOSTAT": 1.891833743985177, "FENTANYL": 1.854111490329393, "FILGRASTIM": 2.0478365526759195, "FIRDAPSE": 2.0039097184111743, "FORSTEO": 1.4826633408538608, "FORXIGA": 0.2799966453247119, "FULVESTRANT": 0.6503310655310592, "GANCICLOVIR": 8.32610468249326, "GARDASIL": 0.2279026759210945, "GAZYVARO": 2.447808065294266, "GEFITINIB": 2.752943612368452, "HALAVEN": 1.7246046382428697, "HARVONI": 1.0336912829214528, "HERCEPTIN": 1.502531813775946, "HIZENTRA": 0.4183425395343074, "HUMALOG": 0.2384181541569299, "HUMAN": 2.1763832499451805, 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0.5603102922133962, "LAMIVUDINE": 1.5275058448519183, "LANTUS": 0.2195037041972757, "LEMTRADA": 0.442343790119854, "LENVIMA": 0.5179771915406706, "LEVETIRACETAM": 2.297251502401876, "LEVOFLOXACIN": 1.9463931724928227, "LONSURF": 0.6367564740998607, "LOPINAVIR": 2.28957457415554, "LYNPARZA": 0.3307201125485063, "LYRICA": 1.3856535446820648, "MABTHERA": 1.7028887355469329, "MANNITOL": 3.8669756186899074, "MEKINIST": 0.5652527102012479, "MELPHALAN": 3.8323219097854153, "MEPOLIZUMAB": 0.7133336908106381, "MERCAPTOPURINE": 1.3055996859889096, "METHOTREXATE": 1.2935155628874933, "MICAFUNGIN": 7.315716756677744, "MICARDIS": 0.7609262188284975, "MIDAZOLAM": 5.498225988630641, "MIRCERA": 0.911433150416157, "MULTAQ": 0.8023267804256387, "MYCAMINE": 3.365628513251994, "MYCOPHENOLATE": 2.507749399276135, "NAGLAZYME": 6.039885750628067, "NALOXONE": 3.3168000889422515, "NEULASTA": 0.6069718111942576, "NEXAVAR": 0.7660570949713266, "NORVIR": 0.6141653543933782, "NOT": 1.0655446010384813, "NOVONORM": 1.166606695734834, "NOVOSEVEN": 1.238937038356688, "NOXAFIL": 2.229926230001312, "NPLATE": 3.5674427997462823, "NUCALA": 0.8756581618520296, "OBINUTUZUMAB": 1.6155991043456723, "OFEV": 4.068429121951681, "OLANZAPINE": 1.132142400192737, "OMALIZUMAB": 0.185283937635719, "ONCASPAR": 1.0035179914427468, "ONGLYZA": 2.1984272934319566, "OPDIVO": 1.1600510277267229, "OPSUMIT": 4.967973681548554, "OPTIMARK": 0.4188343799528646, "ORKAMBI": 3.85124361039721, "OSELTAMIVIR": 4.056413338837996, "OSIMERTINIB": 4.806146009318086, "OXYBUTYNIN": 1.7492452033291133, "PACLITAXEL": 0.9321623175109012, "PANTOPRAZOLE": 0.3096896301250026, "PEGASYS": 0.5919669477597861, "PEGINTRON": 1.138390522002341, "PEMBROLIZUMAB": 2.170282112165836, "PEMETREXED": 4.325080090343241, "PLAVIX": 1.060957569298495, "POSACONAZOLE": 4.212917138258193, "PRADAXA": 1.2088589458007046, "PRAXBIND": 4.29714759175005, "PREGABALIN": 0.6171147507648459, "PRIALT": 9.2616198754291, "PRIVIGEN": 1.122042785967955, "QARZIBA": 4.897998665940421, "RAPAMUNE": 2.5002341475725047, "RASBURICASE": 10.89825260181389, "RELVAR": 0.6566751766411163, "REMDESIVIR": 10.433139685262187, "REMICADE": 0.6036189264086628, "REVATIO": 4.63222267073336, "REVLIMID": 1.1303073795786511, "RIBAVIRIN": 0.6776065456035049, "RILUTEK": 3.777063594567253, "RINVOQ": 0.5985451449961471, "RISPERIDONE": 0.8358661058679601, "RITUXIMAB": 1.944943954677821, "ROACTEMRA": 1.3571169677847197, "ROTATEQ": 0.3592039123788444, "RUXOLITINIB": 2.512734333567904, "SHINGRIX": 0.0890932408175725, "SILDENAFIL": 2.6556613471057844, "SIMPONI": 0.2933054303847471, "SIRTURO": 11.78429460621224, "SOLIRIS": 2.466861979280231, "SOVALDI": 0.5025535938071561, "SPIKEVAX": 0.1963696550943772, "SPINRAZA": 9.519181722401813, "SPRYCEL": 1.71994615562502, "STELARA": 0.310680679817836, "STIVARGA": 0.393663491086162, "SUBOXONE": 0.6757480226138531, "SUGAMMADEX": 24.706460043659813, "SUTENT": 1.3081257187854387, "SYNAGIS": 7.962491396878717, "TACROLIMUS": 2.0172091985146725, "TAGRISSO": 2.934155550665392, "TAMIFLU": 2.899678028254671, "TASIGNA": 0.6686722415020311, "TAXOTERE": 1.80726744292396, "TEMODAL": 1.38383519950582, "THALIDOMIDE": 1.3697589532393957, "TICAGRELOR": 0.8005886030959001, "TOBRAMYCIN": 1.910018192286017, "TOCILIZUMAB": 2.244455095856854, "TOPOTECAN": 2.036617416230893, "TORISEL": 1.6750431596924038, "TOZINAMERAN": 0.1222850567947467, "TRACLEER": 10.224176765992247, "TRELEGY": 2.586302110750671, "TRULICITY": 0.2382978168651847, "TRUVADA": 0.073405050196056, "VAXZEVRIA": 0.0817040209446468, "VEKLURY": 12.782518229360257, "VELTASSA": 0.5537627278470296, "VENCLYXTO": 1.9265764155854583, "VENETOCLAX": 1.1147444953425658, "VFEND": 3.3646688480188804, "VIAGRA": 0.6173726658027202, "VORICONAZOLE": 3.9545349684794857, "VOTRIENT": 0.840781743782349, "XALKORI": 4.1897008015920125, "XARELTO": 2.8779032054692766, "XELJANZ": 0.430143711695068, "XOLAIR": 1.4297748446961798, "XTANDI": 0.6718521015660094, "YERVOY": 1.1962937879179427, "YESCARTA": 1.340213908512469, "YONDELIS": 1.835945610604877, "ZAVESCA": 9.326005181766714, "ZOSTAVAX": 0.4162625006342842, "ZYPREXA": 1.5363688613403637, "null": 1.3943092804010837}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/104.json
index f7a4d2d0278..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/104.json
@@ -1 +1 @@
-{"ATRIPLA": 4.597739131253828, "BIKTARVY": 23.28897853761737, "ISENTRESS": 65.64099724312108, "KALETRA": 61.78360871536852, "VIAGRA": 11.27570503361228}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1040.json
index bcdc214ed4f..a3eafced072 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1040.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1040.json
@@ -1 +1 @@
-{"BUDESONIDE": 1.9618354418914237, "BUPRENORPHINE": 4.677106849785689, "CARFILZOMIB": 13.588368742216788, "CELLCEPT": 2.663199032723325, "CLOPIDOGREL": 1.0554303306368995, "CYTARABINE": 6.377455557356458, "DEXAMETHASONE": 3.12477553573266, "ELIQUIS": 3.0479205858603358, "EXFORGE": 2.2341301141439827, "EXJADE": 2.46488971672355, "HUMALOG": 1.205569520644691, "HUMIRA": 1.6750127905599006, "IBRANCE": 3.10317920404061, "JAKAVI": 2.4033965640844133, "JANUVIA": 1.6645619862810923, "LANTUS": 1.2775118367292393, "LEVOFLOXACIN": 1.2950442820741923, "LYRICA": 2.31766545575503, "METHOTREXATE": 1.607347016539414, "PEGASYS": 2.9058122341275303, "PEGINTERFERON": 9.098414215858968, "PEGINTRON": 7.340849029817821, "PLAVIX": 2.44863060689101, "REVATIO": 4.327913353740692, "ROACTEMRA": 1.890941605239316, "SPRYCEL": 5.0115704348312615, "SUTENT": 3.284611634510012, "VFEND": 6.716272222252268, "VIAGRA": 1.701896400419257, "XELJANZ": 1.8359266375252223, "ZOSTAVAX": 3.5760586578067883, "null": 1.0101096901691096}
\ No newline at end of file
+{"NPLATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10400.json
new file mode 100644
index 00000000000..a2b752fcbb6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10400.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.8444973325082936, "SPIKEVAX": 1.6365173635784689, "VAXZEVRIA": 0.872781941381554, "null": 0.6250597875159594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10401.json
new file mode 100644
index 00000000000..88de0a9ff8c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10401.json
@@ -0,0 +1 @@
+{"null": 0.9899765831711672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10402.json
new file mode 100644
index 00000000000..c192e552139
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10402.json
@@ -0,0 +1 @@
+{"AVAMYS": 64.98299537735419, "MEPOLIZUMAB": 39.50302951491969, "null": 1.4136643433025375}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10403.json
new file mode 100644
index 00000000000..154e4f800c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10403.json
@@ -0,0 +1 @@
+{"null": 1.645098405709401}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10404.json
new file mode 100644
index 00000000000..ac3da746dc2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10404.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3850425307836702, "null": 0.5847242997146401}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10405.json
new file mode 100644
index 00000000000..b23ca03e3a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10405.json
@@ -0,0 +1 @@
+{"CELECOXIB": 1255.7592321339732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10406.json
new file mode 100644
index 00000000000..653162460c8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10406.json
@@ -0,0 +1 @@
+{"null": 7.11388722272033}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10407.json
new file mode 100644
index 00000000000..234fc37e101
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10407.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 2.07891403883624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10408.json
new file mode 100644
index 00000000000..71498d28ffd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10408.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 5.968839978998704, "COMIRNATY": 0.2120539847686932, "FENTANYL": 10.210525473832822, "IBUPROFEN": 3.916039449757093, "KEPPRA": 2.2494053746424214, "LYRICA": 9.057045799591208, "MIDAZOLAM": 6.054258652488604, "OMALIZUMAB": 4.997436598096935, "SPIKEVAX": 0.1166346601385055, "SUBOXONE": 2.0823832776314752, "TOBRAMYCIN": 25.097384826881523, "TOZINAMERAN": 0.8184954293658544, "VAXZEVRIA": 0.2567435257850454, "ZYPREXA": 2.668268690365525, "null": 2.6537546884337413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10409.json
new file mode 100644
index 00000000000..f4752adb9e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10409.json
@@ -0,0 +1 @@
+{"AFINITOR": 3.131052273949986, "BEVACIZUMAB": 1.9849908892533243, "BUDESONIDE": 1.0556711537284822, "CICLOSPORIN": 0.4591088256423818, "CLOPIDOGREL": 6.172391619655951, "COMIRNATY": 0.4914845912748257, "CYMBALTA": 0.9235783223809771, "ENTRESTO": 0.900133727500312, "ESBRIET": 1.9847074378171528, "EXJADE": 0.958690476024608, "FASENRA": 1.9250330646695537, "FENTANYL": 1.3712741999445783, "FLEBOGAMMA": 40.62222287428656, "GARDASIL": 0.7063781313707903, "HYDROCORTISONE": 3.853196918532487, "INSULIN": 1.7681377251726054, "KALETRA": 2.1251294359659343, "KEPPRA": 0.6891127205462074, "KYMRIAH": 3.822219750053017, "LACOSAMIDE": 6.409744742454692, "LEVOFLOXACIN": 1.2211108197125249, "MEPOLIZUMAB": 2.139448631381805, "METHOTREXATE": 1.4824694195172272, "MIDAZOLAM": 6.4124608686099975, "NAGLAZYME": 5.705635668774408, "OFEV": 3.1611292400371265, "OLANZAPINE": 1.0442717222592166, "OMALIZUMAB": 7.518202008120821, "PRIVIGEN": 14.939767562216788, "RITUXIMAB": 1.5478889806659528, "SPIKEVAX": 0.3405210793017824, "STIVARGA": 1.8941806167938215, "SUTENT": 0.4098206094896092, "SYNAGIS": 8.809528506131956, "TICAGRELOR": 6.941773923038289, "TOZINAMERAN": 1.2448534035664442, "VALSARTAN": 5.760275060467538, "VAXZEVRIA": 0.6396045252436007, "XOLAIR": 5.157380116918331, "ZOSTAVAX": 0.6307363383437267, "ZYPREXA": 0.7439694759093023, "null": 1.5023681769091186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1041.json
index 1aac1c254bf..d89cd5b70e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1041.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1041.json
@@ -1 +1 @@
-{"null": 1.2243969595857331}
\ No newline at end of file
+{"null": 0.5447738916505026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10410.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10410.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10411.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10411.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10412.json
new file mode 100644
index 00000000000..dd6c4e48c72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10412.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 41.88759750196953, "ANORO": 199.92470116922703, "APIXABAN": 5.473447712300132, "AVAMYS": 4.034955638732342, "AZATHIOPRINE": 16.936624015530686, "BUDESONIDE": 4.246787092756077, "COMIRNATY": 1.0312244021040384, "GLYCOPYRRONIUM": 25.36879956410619, "IBUPROFEN": 4.261932366142071, "JANUMET": 4.049809171163564, "MEPOLIZUMAB": 10.724366934752467, "METHOTREXATE": 17.52584556303686, "MIDAZOLAM": 6.967604002117082, "NUCALA": 12.578101933184485, "ORKAMBI": 23.92436941742956, "SPIKEVAX": 0.5428657428250796, "TOZINAMERAN": 0.5664509231441386, "VAXZEVRIA": 0.5425595079869683, "null": 0.3637559447676837}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10413.json
new file mode 100644
index 00000000000..dc546e7727e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10413.json
@@ -0,0 +1 @@
+{"SYNAGIS": 12149.277701894092, "null": 0.0645205004753906}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10414.json
new file mode 100644
index 00000000000..651b6bfc07a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10414.json
@@ -0,0 +1 @@
+{"SYNAGIS": 2095.93597987918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10415.json
new file mode 100644
index 00000000000..b810b2f977d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10415.json
@@ -0,0 +1 @@
+{"CIMZIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10416.json
new file mode 100644
index 00000000000..93488c683d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10416.json
@@ -0,0 +1 @@
+{"ADCIRCA": 24.41211866780808, "ALEMTUZUMAB": 4.161180326374071, "APREPITANT": 11.862777383961882, "BUDESONIDE": 5.0553232680204365, "BUSULFAN": 3.965564028614153, "CELLCEPT": 1.1795398325859263, "CICLOSPORIN": 2.3759041033642254, "CYTARABINE": 2.9732110193388244, "DEXAMETHASONE": 1.2290896878332571, "ELIQUIS": 0.4196075904815001, "HIZENTRA": 4.198888362557592, "HUMIRA": 3.071752106648076, "IBRANCE": 0.5054964920856161, "METFORMIN": 11.58714688475367, "OPSUMIT": 3.4780098603198635, "ORKAMBI": 10.525695005938278, "ROTATEQ": 5.095594102355359, "SPINRAZA": 45.103951379338014, "SYNAGIS": 2194.961432432083, "TADALAFIL": 47.11616481082915, "TRACLEER": 2.4661660381695563, "XELJANZ": 0.4195973284375135, "XOLAIR": 0.676799729338451, "null": 0.3421252662753438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10417.json
new file mode 100644
index 00000000000..25a747e0107
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10417.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 7.837596646279589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10418.json
new file mode 100644
index 00000000000..82d54650d55
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10418.json
@@ -0,0 +1 @@
+{"APIXABAN": 15.402543134457806, "SYNAGIS": 4984.922324601891}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10419.json
new file mode 100644
index 00000000000..d9108a619ce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10419.json
@@ -0,0 +1 @@
+{"null": 5.097785270049668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1042.json
index c322daee2a4..82da9c827b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1042.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1042.json
@@ -1 +1 @@
-{"null": 1.835218829352996}
\ No newline at end of file
+{"null": 2.037957290839981}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10420.json
new file mode 100644
index 00000000000..914da7c6aa4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10420.json
@@ -0,0 +1 @@
+{"ABATACEPT": 2.87375404461545, "ARAVA": 6.739397877362917, "CELLCEPT": 3.059440141374164, "CICLOSPORIN": 1.1719966227136625, "CIMZIA": 1.4999982554802525, "COMIRNATY": 0.1078076619976516, "COSENTYX": 3.044667913102903, "ELIQUIS": 1.2690468875150582, "ENBREL": 1.3527088895046224, "FASENRA": 2.917625099394084, "GARDASIL": 0.743698388615894, "HIZENTRA": 2.994839541279018, "HUMIRA": 2.643049216343457, "IBRANCE": 1.358744152342013, "INCRUSE": 12.982931428156302, "JANUVIA": 1.4136263593079543, "MEPOLIZUMAB": 14.83630991418676, "METHOTREXATE": 2.6041421242068084, "NUCALA": 2.9106930629131647, "OMALIZUMAB": 20.16810379728515, "OPSUMIT": 4.498632647076335, "PEGASYS": 2.5453298115621683, "REVATIO": 5.1630924645837615, "SPIKEVAX": 0.9319504367371214, "SPRYCEL": 3.682723173175603, "SUTENT": 0.6216792264800826, "SYNAGIS": 20.37157531997831, "TOZINAMERAN": 0.9224987856012652, "TRELEGY": 4.384575882807394, "VAXZEVRIA": 0.0392886926864885, "XELJANZ": 3.105213828048882, "XOLAIR": 11.02649695039315, "null": 0.8391035296364547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10421.json
new file mode 100644
index 00000000000..59acf436a9c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10421.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 28.54392114751265, "COMIRNATY": 0.3157292447731318, "ENOXAPARIN": 26.94783589277099, "PLAVIX": 11.71276628851296, "SPIKEVAX": 0.3503036742035642, "TICAGRELOR": 38.35344174403821, "null": 0.7501957403783551}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10422.json
new file mode 100644
index 00000000000..583196c8637
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10422.json
@@ -0,0 +1 @@
+{"PRIVIGEN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10423.json
new file mode 100644
index 00000000000..84adc192a76
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10423.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.1058623499835827, "AFINITOR": 0.8536302058336466, "AIMOVIG": 0.626429246782851, "APIXABAN": 0.7763458573697047, "ARAVA": 0.381166615517031, "ARZERRA": 14.017825957177514, "AUBAGIO": 1.415003999069812, "AVAMYS": 16.880285945499573, "AZACITIDINE": 2.3763094965132394, "AZTREONAM": 18.13877969437827, "BENLYSTA": 2.5195299821805874, "BORTEZOMIB": 3.701934198328236, "BUDESONIDE": 2.056813947757735, "BUPRENORPHINE": 1.2446465977233152, "CARFILZOMIB": 4.526327821667148, "CELLCEPT": 2.0306064037897342, "CHAMPIX": 0.5890211919984695, "CICLOSPORIN": 1.8444805626844507, "CIMZIA": 1.4408408842152345, "CLOPIDOGREL": 0.2278582991643065, "COMIRNATY": 0.2125539660958771, "COSENTYX": 3.142004953379431, "CYTARABINE": 0.8024437631927751, "DARATUMUMAB": 9.363441124372097, "DARZALEX": 2.1134895642540177, "DEXAMETHASONE": 1.7080482320295536, "DULOXETINE": 1.7891354710821918, "ELIQUIS": 0.4102494213263301, "ENBREL": 1.968474683621432, "ENTRESTO": 1.174287758212515, "ESBRIET": 3.217179197535148, "EXJADE": 0.5097918186175, "FASENRA": 1.907551445394119, "FLUTICASONE": 11.920756091004456, "FORSTEO": 1.218157277157652, "FULVESTRANT": 1.330726438294939, "GARDASIL": 0.3573751486282076, "GAZYVARO": 10.827224774667783, "HIZENTRA": 21.68055403648957, "HUMALOG": 0.2409226829696001, "HUMAN": 2.492866455782184, "HUMIRA": 0.9559145246594388, "HYQVIA": 10.073441185151372, "IBRANCE": 0.9328891776403154, "INCIVO": 2.2636438948909268, "INCRUSE": 9.707100258518134, "INFANRIX": 2.5450952612485733, "JAKAVI": 4.0697262845954, "JANUVIA": 0.5549210570021575, "JARDIANCE": 0.6709064045070527, "KEPPRA": 0.7555658331905816, "KESIMPTA": 3.871728013760523, "KEYTRUDA": 0.7285758125473663, "KYPROLIS": 6.063136943316445, "LACOSAMIDE": 1.649367325297178, "LANTUS": 0.6863936871538563, "LEVETIRACETAM": 0.9330765889019346, "LEVOFLOXACIN": 1.1234634696002184, "MABTHERA": 2.403266910951043, "MEPOLIZUMAB": 6.455759477256253, "METHOTREXATE": 5.380784836710125, "MMRVAXPRO": 2.498024128645964, "MYCOPHENOLATE": 1.6508529287581286, "NAGLAZYME": 6.334084435864783, "NEXAVAR": 0.7466312999432937, "NPLATE": 1.736472379611234, "NUCALA": 6.310682643521073, "OFEV": 1.8610907113663289, "OMALIZUMAB": 21.579277049734447, "OPSUMIT": 1.8455811348101547, "ORKAMBI": 5.24819095864479, "PEGASYS": 1.0565463416899523, "PEGINTERFERON": 0.8407289358643774, "PEGINTRON": 0.4322228781861736, "PRIVIGEN": 2.176885876082865, "RELVAR": 4.927005773753839, "REVATIO": 1.1388183166121664, "RINVOQ": 4.802190196783728, "RITUXIMAB": 2.9592777501163483, "ROACTEMRA": 3.2535090173111576, "ROTATEQ": 1.7783734577486614, "RUCONEST": 4.417830492592935, "SIMPONI": 4.767905110851841, "SOLIRIS": 4.524754743733026, "SPIKEVAX": 0.1029217122238192, "SPINRAZA": 31.54222771694424, "SPRYCEL": 1.1397318310062736, "STELARA": 2.9986910778153164, "SUTENT": 0.1922820965390957, "SYNAGIS": 15.948728751093402, "TOZINAMERAN": 0.154733921264879, "TRACLEER": 4.215746945787666, "TRELEGY": 2.378655061929241, "TREMFYA": 4.388196650206216, "VAXZEVRIA": 0.0541127999852571, "VENCLYXTO": 4.994230510786925, "VFEND": 1.486129603512787, "VOTRIENT": 0.5761806644140979, "XELJANZ": 5.279282044852707, "XOLAIR": 4.308261556089283, "XTANDI": 0.5353431768269045, "ZOSTAVAX": 0.4032599832205729, "null": 0.8520364750868805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10424.json
new file mode 100644
index 00000000000..293d104f9ba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10424.json
@@ -0,0 +1 @@
+{"null": 0.594660458766305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10425.json
new file mode 100644
index 00000000000..1d505696b0b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10425.json
@@ -0,0 +1 @@
+{"BUSULFAN": 41.7443111865362, "OMALIZUMAB": 27.66823789647862, "null": 0.4871418973371245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10426.json
new file mode 100644
index 00000000000..4c2c21892c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10426.json
@@ -0,0 +1 @@
+{"ARAVA": 2.4297915697564094, "CICLOSPORIN": 2.688166166967562, "OPSUMIT": 5.846808365901286, "SIMPONI": 4.62300943454808, "SOLIRIS": 6.818974218135487, "SPINRAZA": 47.9386322924686, "SYNAGIS": 28.712924966134054, "TRACLEER": 8.63540280505277, "null": 0.8651426235175133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10427.json
new file mode 100644
index 00000000000..082451d784a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10427.json
@@ -0,0 +1 @@
+{"AVAMYS": 27.92944448162877, "COMIRNATY": 0.4043114966742816, "NUCALA": 17.543568887843726, "null": 1.0212203828098814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10428.json
new file mode 100644
index 00000000000..9916fc68683
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10428.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9302974062553176, "QUTENZA": 112.0339539867263, "SPIKEVAX": 0.5876473837962397, "TOZINAMERAN": 1.0759226102836226, "VAXZEVRIA": 0.5738674012207268, "null": 2.003055295261916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10429.json
new file mode 100644
index 00000000000..6f57bfc689b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10429.json
@@ -0,0 +1 @@
+{"DULOXETINE": 179.52236981638814, "null": 1.722962529067409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1043.json
index 722c93ac6a5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1043.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1043.json
@@ -1 +1 @@
-{"PEGASYS": 3.5058034967179688, "null": 1.4752344021968995}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10430.json
new file mode 100644
index 00000000000..28a31734969
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10430.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.762822865868362, "RUCONEST": 268.59597081081745, "SPIKEVAX": 0.4499834992446258, "TOZINAMERAN": 1.6123993493495905, "VAXZEVRIA": 0.1559445694916644, "null": 1.3761002101990385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10431.json
new file mode 100644
index 00000000000..ad74792f2a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10431.json
@@ -0,0 +1 @@
+{"NUCALA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10432.json
new file mode 100644
index 00000000000..7ae26a3475d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10432.json
@@ -0,0 +1 @@
+{"SPINRAZA": 1034.927608000197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10433.json
new file mode 100644
index 00000000000..13c480c971c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10433.json
@@ -0,0 +1 @@
+{"MERCAPTOPURINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10434.json
new file mode 100644
index 00000000000..f23c5534766
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10434.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.2409720988589985, "SPIKEVAX": 3.192804128051728, "VAXZEVRIA": 2.438351307747542, "null": 0.1923423140629272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10435.json
new file mode 100644
index 00000000000..920525fded3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10435.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 14.274465229510971, "COMIRNATY": 0.1308642493603938, "ENTACAPONE": 234.97208418261712, "OLANZAPINE": 34.26942861664295, "SPIKEVAX": 0.2278976444414202, "VAXZEVRIA": 0.2448679508310804, "null": 2.0290686720628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10436.json
new file mode 100644
index 00000000000..b4ff0a3a755
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10436.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7981841352364151, "VAXZEVRIA": 1.3777908778276386, "null": 1.223520181574243}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10437.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10437.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10438.json
new file mode 100644
index 00000000000..4bbac641e47
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10438.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.921978349099547, "AIMOVIG": 1.9347172857442927, "ARIPIPRAZOLE": 2.8839581706793047, "AUBAGIO": 1.0412861508769742, "BRINTELLIX": 6.115806096278832, "BUPRENORPHINE": 0.8186975892027251, "BYDUREON": 1.582824247070272, "CARBIDOPA": 6.669665471513686, "CHAMPIX": 0.910474219064062, "CIRCADIN": 10.03443665016759, "COMIRNATY": 0.5403060778486649, "COSENTYX": 0.3713885656468067, "CYMBALTA": 3.075192488312809, "CYTARABINE": 0.6632317626974148, "ELIQUIS": 0.3985412267668388, "ENBREL": 2.000614616833089, "ENZALUTAMIDE": 4.468926961792873, "FAMPYRA": 3.873817295404484, "FASLODEX": 0.897947840306769, "FENTANYL": 0.6193552091326665, "FIRDAPSE": 2.5400433727668816, "FORSTEO": 1.665473051659692, "GARDASIL": 0.7999878647696741, "HUMIRA": 0.6932719696710615, "IBRANCE": 0.4727323818692164, "IBUPROFEN": 0.7311320926479676, "JANUVIA": 0.4929359993152566, "KEPPRA": 0.5669820833527778, "LATUDA": 5.713083208448298, "LYRICA": 1.6886276454854752, "MELATONIN": 2.561572875498012, "METHOTREXATE": 0.6025976682944276, "MIRABEGRON": 13.378735557660166, "NEUPRO": 44.914537122909735, "OCRELIZUMAB": 2.3147052682139906, "OLANZAPINE": 2.7536926975378235, "OXYBUTYNIN": 5.103425248562036, "PANTOPRAZOLE": 1.147791928673758, "PEGASYS": 0.3881271109043078, "SIFROL": 28.826429076411973, "SPIKEVAX": 0.5020821096390486, "STELARA": 0.3668874240172945, "SUBOXONE": 2.4325764990381638, "SYCREST": 12.21988547548867, "TASIGNA": 0.7835227809002949, "TOZINAMERAN": 0.7910753192101191, "VAXZEVRIA": 0.9542844579168815, "XELJANZ": 0.5922376703722971, "XOLAIR": 0.7082547192110731, "XTANDI": 5.586587972308941, "XYREM": 4.735675121532666, "ZOSTAVAX": 4.208132013531711, "ZYPADHERA": 5.691738086625223, "ZYPREXA": 2.030360964883424, "null": 1.7592399490562665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10439.json
new file mode 100644
index 00000000000..50780f83e60
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10439.json
@@ -0,0 +1 @@
+{"ABILIFY": 4.188663766654194, "AERIUS": 2.0273885633136373, "AIMOVIG": 1.528958998252493, "ARIPIPRAZOLE": 3.140797179027577, "ATRIPLA": 0.066359681984742, "AUBAGIO": 0.2561319202001538, "AXURA": 15.078464057384542, "AZILECT": 6.917255517134564, "BENLYSTA": 0.2690880779961622, "BENZODIAZEPINE": 1.7068738427629169, "BETMIGA": 0.9165810495973628, "BEXSERO": 2.3905148195120827, "BRIDION": 0.8326129734474111, "BRINTELLIX": 4.044732120258892, "BRIVIACT": 1.9687915150800608, "BUDESONIDE": 0.1962654158755656, "BUPIVACAINE": 0.6505794225703896, "BUPRENORPHINE": 1.6287181697192723, "CANNABIDIOL": 3.7253722683522814, "CAPECITABINE": 0.4369926184831035, "CELLCEPT": 0.2015427934245735, "CHAMPIX": 3.5071847484222296, "CICLOSPORIN": 0.1451461022774153, "CIRCADIN": 8.214509521560892, "CLOPIDOGREL": 0.3166601385701015, "COMIRNATY": 0.6937825358609009, "COMTAN": 2.429789615765583, "COSENTYX": 0.3209477309226489, "CYMBALTA": 2.364455528251644, "DEXAMETHASONE": 0.8010445447095531, "DEXMEDETOMIDINE": 2.887796844041424, "DULOXETINE": 1.1071213393554913, "ELIQUIS": 0.3422192361850831, "ENTACAPONE": 2.3831185347366843, "ENTRESTO": 0.3256215582281016, "ENTYVIO": 0.2042036300710372, "EXELON": 3.4826921022358106, "EXFORGE": 0.3234288573731561, "FAMPYRA": 1.1776529221157137, "FASENRA": 0.4346219282083588, "FENTANYL": 1.381011362110217, "FORSTEO": 0.5962884626174799, "FORXIGA": 0.2695595367284506, "FYCOMPA": 5.022475043473767, "GARDASIL": 0.7880239906268526, "HEXACIMA": 15.066447653870318, "HEXYON": 14.785199530569392, "HUMALOG": 0.1187345745798607, "HYDROCHLOROTHIAZIDE": 2.075239952543037, "HYDROCORTISONE": 0.9923641367069796, "IBRANCE": 0.1636324131097261, "IBUPROFEN": 0.295355427881134, "INFANRIX": 12.654633772801732, "INVEGA": 2.83979137097494, "IRON": 2.440893830961534, "JANUMET": 0.2114742225885528, "JARDIANCE": 0.2678244965131396, "KAFTRIO": 2.0368500877271343, "KEPPRA": 1.9069622935435624, "KETOCONAZOLE": 4.638658723211905, "KEYTRUDA": 0.1681971857490029, "KIOVIG": 1.26574996246081, "LANTUS": 0.3114706656907527, "LATUDA": 8.107327859828523, "LEMTRADA": 0.4151605195649701, "LEVETIRACETAM": 1.4381032744817297, "LEVODOPA": 3.786702710786704, "LEVOFLOXACIN": 1.2244858206171052, "LYRICA": 1.970647104514076, "MELATONIN": 1.6445819115824682, "MICARDIS": 0.5008974517340842, "MIDAZOLAM": 2.085828060093996, "MIRCERA": 1.5454825462593405, "MMRVAXPRO": 4.237609547414271, "MULTAQ": 0.6608698993175045, "NEXAVAR": 0.0948651830672205, "NIMENRIX": 2.1349906125743776, "NOT": 0.5674110700136081, "OCRELIZUMAB": 0.3339313448343345, "OLANZAPINE": 3.226822623022316, "PANTOPRAZOLE": 0.4426552067375535, "PEGASYS": 0.2996633442181848, "PEGINTRON": 0.185671279386241, "PLAVIX": 0.1408566773873854, "PREGABALIN": 0.9628441148590456, "PREVENAR": 8.421711360481714, "PRIVIGEN": 0.7453555722551705, "PROPRANOLOL": 2.4330846415611385, "REAGILA": 22.96105733939289, "RELVAR": 0.7499214997069885, "RISPERIDONE": 2.822311877252325, "ROACTEMRA": 0.2736964305783528, "ROTATEQ": 6.300355761948159, "SAXENDA": 0.3499484446329607, "SHINGRIX": 0.5145467818799712, "SIFROL": 3.698603996491606, "SIMPONI": 0.0999753278159167, "SOLIRIS": 0.1652412271374954, "SPIKEVAX": 0.4719004352369794, "STALEVO": 1.119742980727795, "STELARA": 0.2026270298565913, "SUBOXONE": 2.5983832599891765, "SUTENT": 0.2087746781735334, "SYCREST": 6.105658585660609, "SYNAGIS": 0.7814129937304163, "TAMIFLU": 3.1185272726100086, "TELMISARTAN": 1.130740579628989, "TOVIAZ": 0.497330708582324, "TOZINAMERAN": 0.4354583249652923, "TRUVADA": 0.0348185289765065, "TWINRIX": 0.7645804516741815, "VALDOXAN": 15.99707350382211, "VAXZEVRIA": 0.617374998688677, "VFEND": 3.5784392930744198, "VIMPAT": 1.8819833072486536, "VORICONAZOLE": 2.12146036490312, "XELJANZ": 0.1335730687555502, "XEPLION": 8.82870357852778, "XOLAIR": 0.3519227939393126, "XTANDI": 0.4097379945322061, "XYREM": 0.8301863523739924, "ZOSTAVAX": 0.1014649906393316, "ZYPADHERA": 13.4418961201057, "ZYPREXA": 3.253754722018797, "null": 2.3679645863024867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1044.json
index d3df5c25dc7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1044.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1044.json
@@ -1 +1 @@
-{"FENTANYL": 1060.8809749451864}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10440.json
new file mode 100644
index 00000000000..fbac92640bc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10440.json
@@ -0,0 +1 @@
+{"null": 1.2946196262185097}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10441.json
new file mode 100644
index 00000000000..39f6e11ce1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10441.json
@@ -0,0 +1 @@
+{"AVAMYS": 20.29497736654046, "NUCALA": 14.665423541525032, "OMALIZUMAB": 12.298080668952414, "null": 0.9830081323202178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10442.json
new file mode 100644
index 00000000000..4e613f8e43a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10442.json
@@ -0,0 +1 @@
+{"BRIDION": 17.91107453233407, "COMIRNATY": 0.6604928799942434, "FENTANYL": 3.054935513065892, "INFANRIX": 21.22073000274764, "KEPPRA": 3.737895731426117, "MIDAZOLAM": 10.406395131228765, "SPIKEVAX": 0.989230183368682, "TRACLEER": 9.112999858904097, "VAXZEVRIA": 0.1605620822524174, "null": 1.4729846457624258}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10443.json
new file mode 100644
index 00000000000..093c4b3085e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10443.json
@@ -0,0 +1 @@
+{"null": 2.275852999197769}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10444.json
new file mode 100644
index 00000000000..8439249f9b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10444.json
@@ -0,0 +1 @@
+{"STELARA": 6.983670274392944, "null": 15.320769091454585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10445.json
new file mode 100644
index 00000000000..0c403eccdd9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10445.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.8091435908992763, "ADEMPAS": 2.6671319913359435, "AFINITOR": 0.5655573570229068, "AIMOVIG": 0.3182081332012978, "BENLYSTA": 0.885316875861359, "BRINTELLIX": 1.955767781240315, "BUPRENORPHINE": 0.6081455074831813, "BYDUREON": 0.5786225016044251, "BYETTA": 1.0927545587639726, "CAPECITABINE": 0.9324959829720536, "CHAMPIX": 2.1300898234943406, "CIMZIA": 0.3126641454768803, "CLOPIDOGREL": 1.2224520381410646, "COMIRNATY": 0.6419316772331458, "CYMBALTA": 0.8195735061153944, "DEXAMETHASONE": 0.8104524651791846, "ELIQUIS": 0.3107035390534409, "ESBRIET": 1.2418372609347763, "EXJADE": 0.6428769759721293, "FASLODEX": 0.8117454382247611, "FENTANYL": 0.683348562836704, "FORSTEO": 1.5167313658010793, "GARDASIL": 0.9752198063110004, "GONALF": 6.3100895518501545, "HUMALOG": 0.6883534586873569, "IBRANCE": 1.335120337233339, "IBUPROFEN": 3.055541230683626, "INSULIN": 0.6995753014343086, "IRINOTECAN": 1.432393007527164, "JANUMET": 1.4877883302272803, "JARDIANCE": 0.8298219983417998, "KEPPRA": 0.5527652299360759, "LANTUS": 0.7812189456300141, "LEVOFLOXACIN": 0.6203429245091115, "LYRICA": 0.715083897663953, "MMRVAXPRO": 0.851867969677852, "NEXAVAR": 0.3248637254958274, "NIMENRIX": 1.174361549707677, "OFEV": 1.0348987187175105, "OLANZAPINE": 0.3055660667924471, "OPSUMIT": 1.0236466277255274, "PEGASYS": 1.2205288854692526, "PEGINTRON": 1.0039086556127643, "PLAVIX": 0.4107428424664482, "PRIVIGEN": 1.0819136119626098, "ROTATEQ": 2.35156960741533, "SAXENDA": 0.7467550528413466, "SHINGRIX": 0.4743731650770657, "SPIKEVAX": 0.7779639356037157, "STELARA": 0.2435841314911261, "SUBOXONE": 0.3550530273257533, "SUTENT": 2.907189859546843, "TAMIFLU": 1.326101256890914, "TOZINAMERAN": 0.9040020222658678, "TRELEGY": 2.3979612135348294, "TRULICITY": 2.473882452579214, "VAXZEVRIA": 0.9366502721786972, "VICTOZA": 2.2572951491565862, "VIMPAT": 1.1252202810631002, "VOTRIENT": 1.7765678829408376, "XELJANZ": 0.2879697607945898, "XELODA": 2.153909571237612, "XOLAIR": 0.7447310592325617, "XTANDI": 1.406297639558207, "ZOSTAVAX": 0.2422306075645816, "ZYPREXA": 0.2919541949351766, "null": 1.892249007737025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10446.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10446.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10447.json
new file mode 100644
index 00000000000..6f67beeb341
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10447.json
@@ -0,0 +1 @@
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10448.json
new file mode 100644
index 00000000000..86138c9639e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10448.json
@@ -0,0 +1 @@
+{"ARANESP": 193.1956313031387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10449.json
new file mode 100644
index 00000000000..855699bfd93
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10449.json
@@ -0,0 +1 @@
+{"ARANESP": 111.9777727390904, "CICLOSPORIN": 5.886978633261736, "MIRCERA": 169.81047159311254, "PEGASYS": 3.308455097905944, "null": 0.888600408405927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1045.json
index e722cd9c56f..92cd1de9878 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1045.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1045.json
@@ -1 +1 @@
-{"FENTANYL": 58.98155573860414, "null": 1.9662913221615863}
\ No newline at end of file
+{"null": 1.026910336749472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10450.json
new file mode 100644
index 00000000000..1711a653820
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10450.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 11.124090875657998, "EXJADE": 23.22915423843535, "JAKAVI": 14.126711586317986, "PRIVIGEN": 31.62206682594228, "SOLIRIS": 112.8348654957322, "null": 0.6481127871428313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10451.json
new file mode 100644
index 00000000000..d22ea2347d8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10451.json
@@ -0,0 +1 @@
+{"JAKAVI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10452.json
new file mode 100644
index 00000000000..f764acd0480
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10452.json
@@ -0,0 +1 @@
+{"ARANESP": 66.71399294464669, "null": 0.4101139344244706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10453.json
new file mode 100644
index 00000000000..f4f5c9b4cf6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10453.json
@@ -0,0 +1 @@
+{"SOLIRIS": 45.09404940967795, "null": 1.395388393775952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10454.json
new file mode 100644
index 00000000000..9174c7c7e0c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10454.json
@@ -0,0 +1 @@
+{"null": 0.3495521067868478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10455.json
new file mode 100644
index 00000000000..b4d60c04508
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10455.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8458431782217796, "VAXZEVRIA": 1.0489227983827965, "null": 0.3851805820481266}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10456.json
new file mode 100644
index 00000000000..7caa5ff48e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10456.json
@@ -0,0 +1 @@
+{"AVASTIN": 3.3248211410057165, "BEOVU": 226.58917402096003, "BROLUCIZUMAB": 189.09444054438305, "COMIRNATY": 0.8091603610570621, "ELIQUIS": 0.9818247112498092, "EVISTA": 7.219316153187682, "EYLEA": 94.06121448711548, "HUMALOG": 0.8208862176694982, "ICLUSIG": 7.683465024856064, "LANTUS": 0.944835655455905, "PEGASYS": 1.9812567329697452, "PEGINTRON": 5.978729605743709, "RINVOQ": 3.2205726395740206, "SPIKEVAX": 0.4941132692314486, "TOZINAMERAN": 0.7266114057472959, "VAXZEVRIA": 0.6704876249001012, "VIAGRA": 10.442709032943352, "ZOSTAVAX": 1.1290111781371213, "null": 0.7746648887599001}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10457.json
new file mode 100644
index 00000000000..db7aae691de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10457.json
@@ -0,0 +1 @@
+{"null": 1.358446126336236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10458.json
new file mode 100644
index 00000000000..8dac72697b3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10458.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7090124428221841, "PEGASYS": 4.077166531413983, "PEGINTRON": 16.190850188273497, "VAXZEVRIA": 0.8656257590477695, "VIAGRA": 19.101362640800307, "null": 0.2512166165395845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10459.json
new file mode 100644
index 00000000000..ade5a105f3a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10459.json
@@ -0,0 +1 @@
+{"CARFILZOMIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1046.json
index 28d063c3018..8d052bfebcb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1046.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1046.json
@@ -1 +1 @@
-{"ASPARAGINASE": 17.833106748120954, "CYTARABINE": 13.54617772855821, "DEXAMETHASONE": 5.652027845801441, "JAKAVI": 8.740466280210347, "KYMRIAH": 66.71422532841393, "ROACTEMRA": 28.473692933584942, "null": 1.1807231569557386}
\ No newline at end of file
+{"ABACAVIR": 0.8225221862565613, "ABASAGLAR": 1.4906567939184865, "ABRAXANE": 10.14915246132696, "ACLIDINIUM": 1.7582497135720154, "ADALIMUMAB": 0.299660854166742, "ADCIRCA": 8.199063021325125, "ADEMPAS": 2.994572045662028, "ADENURIC": 2.187343758074655, "AFINITOR": 5.301072828596213, "ALEMTUZUMAB": 1.792437080519588, "ALIMTA": 1.3273225370098023, "AMBRISENTAN": 3.427845662302708, "AMINOSALICYLIC": 1.250189514981529, "APIXABAN": 0.2053908296053716, "ARANESP": 43.554514796245314, "ARAVA": 0.0523456518827239, "ASPARAGINASE": 2.9117593433638747, "ATRIPLA": 0.0715432008880196, "AVANDIA": 1.2860679964480726, "AVASTIN": 3.743761523494976, "AZATHIOPRINE": 1.419994857606694, "BARACLUDE": 6.507745034903077, "BASILIXIMAB": 2.88510586472433, "BEDAQUILINE": 2.4510172527365754, "BEMFOLA": 161.00914269102768, "BENLYSTA": 0.4289212684916949, "BEVACIZUMAB": 4.262528384897177, "BOCEPREVIR": 9.402611649064644, "BORTEZOMIB": 3.767389091003765, "BOSULIF": 0.8373699581777031, "BRAFTOVI": 1.3861775378904917, "BUDESONIDE": 0.1879398756115083, "BUSULFAN": 3.592103124567649, "BYDUREON": 0.457339569487288, "BYETTA": 5.16060959947885, "CABOMETYX": 3.794009366499808, "CAELYX": 4.495874422105774, "CAPECITABINE": 3.827954703293005, "CARFILZOMIB": 2.2309839200119974, "CELLCEPT": 2.308168225319864, "CETROTIDE": 89.61599178002868, "CICLOSPORIN": 2.0162898706578165, "CIMZIA": 0.1072494974914539, "CLOPIDOGREL": 0.4906064911490323, "COMBIVIR": 2.9933114466888284, "COMIRNATY": 0.0523579807180853, "COSENTYX": 0.7017363277120117, "CRIXIVAN": 1.7315016646412813, "CYMBALTA": 0.2961490652971488, "CYTARABINE": 2.2716440856686604, "DACLATASVIR": 15.145343648683788, "DAKLINZA": 4.298027711624499, "DARBEPOETIN": 45.03706912035207, "DARUNAVIR": 3.261998555537949, "DEFITELIO": 8.375447960336, "DEXAMETHASONE": 0.8969066065571119, "DOCETAXEL": 1.3949800062154571, "ELIQUIS": 0.3158364545221658, "EMTRICITABINE": 2.9907718284534512, "ENBREL": 0.1665602885794576, "ENTRESTO": 1.6895710685217418, "ENTYVIO": 0.3326951736747239, "ENVARSUS": 22.175002988121147, "EPCLUSA": 13.8641180105857, "EPIVIR": 2.423103024940346, "ESOMEPRAZOLE": 0.7860081024019623, "EVEROLIMUS": 2.765764743568304, "EXFORGE": 0.5155398600676588, "EXJADE": 1.7475585659519826, "EXVIERA": 38.64683858815975, "FASLODEX": 3.364064570154216, "FENTANYL": 0.3170034559008968, "FLUTICASONE": 10.210597010696176, "FOLLITROPIN": 20.367545688404647, "FULVESTRANT": 2.561487870201096, "GANCICLOVIR": 1.970222675013314, "GLIVEC": 3.7386500859838, "GONALF": 105.59424441643765, "HALAVEN": 1.490877899091061, "HARVONI": 15.005517187332382, "HEPSERA": 2.3581492124856798, "HERCEPTIN": 1.574622375685576, "HUMALOG": 0.1187644926377069, "HUMIRA": 0.2397144006876055, "IBRANCE": 1.9121970511211808, "IBUPROFEN": 0.2528052971222236, "ICLUSIG": 0.876663813194848, "INCIVO": 6.281502988457305, "INFLIXIMAB": 1.3735550545495392, "INLYTA": 1.2428404524098566, "INSULIN": 1.0767462040463365, "INTRONA": 5.518125061279705, "IPILIMUMAB": 0.6286859209635771, "IRESSA": 0.6344526790610371, "IRINOTECAN": 2.860073684042282, "ISENTRESS": 3.731413501676079, "JAKAVI": 4.26574108970212, "JANUMET": 2.008794100403612, "JANUVIA": 2.9548622956717066, "JARDIANCE": 0.1226583468274014, "JEVTANA": 1.1873116707185498, "KALETRA": 1.9992077293007071, "KEYTRUDA": 2.281806779520439, "KISQALI": 1.3146302690575022, "KYMRIAH": 0.7266164116836351, "LAMIVUDINE": 3.254510077463169, "LANTUS": 0.4039293643401722, "LENVIMA": 11.947432428003705, "LEVETIRACETAM": 0.3606786972682265, "LEVOFLOXACIN": 0.2127878216289169, "LONSURF": 6.352302478703547, "LUTATHERA": 5.0770647999392216, "LUVERIS": 23.48742004773497, "LYNPARZA": 3.709310540159764, "MABTHERA": 1.4683384331893126, "MACITENTAN": 5.767481095904413, "MEKINIST": 0.6028550104857396, "MELATONIN": 2.205383080995745, "MELPHALAN": 3.146105082320292, "METHOTREXATE": 0.6195052113689401, "MIDAZOLAM": 0.6961009903726599, "MIDOSTAURIN": 12.16445840759628, "MYCOPHENOLATE": 0.8138537191650227, "NEULASTA": 0.6948887379935228, "NEXAVAR": 14.769718058471272, "NPLATE": 1.828969276955752, "OCALIVA": 15.496527183662744, "OLYSIO": 11.281419352584866, "ONCASPAR": 4.633524375200259, "OPDIVO": 1.2177713568640771, "OPSUMIT": 4.27093406355438, "OPTIMARK": 0.3621094608175088, "ORGALUTRAN": 102.59086172730392, "OVITRELLE": 133.2724701498231, "PACLITAXEL": 2.0264143546980544, "PANTOPRAZOLE": 0.7055858212396481, "PAZOPANIB": 2.204751588921844, "PEGASYS": 4.447282353762029, "PEGINTERFERON": 3.7841851538138807, "PEGINTRON": 3.2844314620525217, "PEMBROLIZUMAB": 1.5843976598429268, "PEMETREXED": 1.1016005954653318, "PLAVIX": 0.1408920446411426, "PUREGON": 12.860592918138916, "RAPAMUNE": 1.998287820557341, "REBETOL": 6.4896854900750505, "REVATIO": 2.539587105426261, "RIBAVIRIN": 8.615231177692301, "RITUXIMAB": 0.7201829731214755, "ROACTEMRA": 0.393840079179668, "RUBRACA": 4.4295438950554695, "SILDENAFIL": 2.1585014095108868, "SIMEPREVIR": 7.538686831364737, "SIMPONI": 0.1822296192485027, "SOFOSBUVIR": 5.870984986841708, "SOLIRIS": 2.339815984259176, "SORAFENIB": 5.550053398271658, "SOVALDI": 9.094616982559542, "SPIKEVAX": 0.0505916317091019, "SPIRONOLACTONE": 2.1123389108606587, "SPRYCEL": 2.69201418445554, "STELARA": 0.2414951039838474, "STIVARGA": 7.269938269043571, "SUBOXONE": 0.1890054159326201, "SUTENT": 4.017895439174292, "TAMIFLU": 0.3130458053304407, "TASIGNA": 1.0905498510269236, "TORISEL": 3.935584745180045, "TOZINAMERAN": 0.0263430847703385, "TRACLEER": 5.747668120628645, "TRODELVY": 1.6989136810832492, "VAXZEVRIA": 0.0214120365370526, "VFEND": 0.3864984528750526, "VIRAMUNE": 6.555868611360491, "VIREAD": 0.8322654172048239, "VOTRIENT": 1.801816983628868, "XALKORI": 1.132337885771065, "XARELTO": 0.6335362393312461, "XELODA": 1.2982650080741345, "XTANDI": 0.2168447996240714, "YERVOY": 1.180958496205376, "ZEPATIER": 5.837390909391751, "ZYPREXA": 0.2764825875447901, "null": 0.6458180045725012}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10460.json
new file mode 100644
index 00000000000..09625d32d70
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10460.json
@@ -0,0 +1 @@
+{"null": 1.5345798162876387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10461.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10461.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10462.json
new file mode 100644
index 00000000000..06c9a921416
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10462.json
@@ -0,0 +1 @@
+{"BEOVU": 96.41387334931284, "COMIRNATY": 0.1626361355141603, "EYLEA": 65.43664434958252, "GANCICLOVIR": 36.80243120887074, "LUXTURNA": 8002.012273288915, "MELPHALAN": 124.06161256418096, "VIAGRA": 15.485430529342086, "ZOSTAVAX": 11.904801075722716, "null": 0.7640102861503596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10463.json
new file mode 100644
index 00000000000..1ffe9145aed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10463.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 19.43908723938297, "null": 0.4140489676554496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10464.json
new file mode 100644
index 00000000000..fa089303f3d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10464.json
@@ -0,0 +1 @@
+{"LUXTURNA": 9965.152892245856, "null": 1.250315058628196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10465.json
new file mode 100644
index 00000000000..1d3310ac221
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10465.json
@@ -0,0 +1 @@
+{"APIDRA": 2.757465254488096, "AVANDIA": 0.7190703769098735, "AVASTIN": 1.753721111014384, "AZATHIOPRINE": 2.3889214086128563, "BRAFTOVI": 23.58744299445615, "BYDUREON": 1.732455151663297, "BYETTA": 1.6429172542761514, "CHAMPIX": 0.4992452117742146, "CICLOSPORIN": 0.8007535192136793, "CIMZIA": 0.3958363248718997, "COBIMETINIB": 19.79946613171682, "COMIRNATY": 0.4052958849008589, "COTELLIC": 15.115697027713354, "CYMBALTA": 1.1847312422123633, "ELIQUIS": 0.6840450301599039, "EXFORGE": 1.7177033263350323, "EYLEA": 26.493331315625667, "GANCICLOVIR": 15.433064259091855, "HUMALOG": 8.587286504986132, "IBRANCE": 0.4588171252063275, "INSULIN": 2.7961704635819347, "JARDIANCE": 0.7811835258578231, "JETREA": 309.59997281586044, "KEYTRUDA": 0.6414299009613796, "LANTUS": 6.718018692208738, "LUXTURNA": 305.5062079943043, "MEKINIST": 13.607838636615742, "OMALIZUMAB": 1.2572259535815424, "PEGASYS": 4.440742394406674, "PEGINTRON": 3.3842548095876235, "PLAVIX": 0.4591672474021094, "RINVOQ": 2.342646398939883, "SHINGRIX": 0.7657519276850162, "SPIKEVAX": 0.4037502278515349, "STELARA": 0.5991031749299637, "STIVARGA": 1.1735360059619004, "SUTENT": 0.5798234802905224, "TAMIFLU": 1.2923625627101658, "TASIGNA": 1.2514081928820189, "TOZINAMERAN": 0.2918289401448297, "TRULICITY": 2.1693043300112214, "VAXZEVRIA": 0.3519361562308731, "VIAGRA": 6.72645592197961, "VOTRIENT": 4.794891790434898, "XELJANZ": 0.8497072951586582, "ZOSTAVAX": 2.503870392008266, "null": 0.8106134471009526}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10466.json
new file mode 100644
index 00000000000..a9c88ba34d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10466.json
@@ -0,0 +1 @@
+{"BEOVU": 26.523705641859674, "COMIRNATY": 0.1203470757485444, "EYLEA": 15.35556104109066, "HUMALOG": 10.5216878081244, "LANTUS": 12.23238895315426, "PEGASYS": 3.690120327247411, "PEGINTRON": 4.0169389983323285, "SPIKEVAX": 0.1158418189472632, "VIAGRA": 5.300067416047055, "VIGABATRIN": 495.6011520809989, "ZOSTAVAX": 2.976871779690246, "null": 1.2169283524733945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10467.json
new file mode 100644
index 00000000000..b2aac13a93d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10467.json
@@ -0,0 +1 @@
+{"BEOVU": 293.47867579839766, "ZOSTAVAX": 23.581240933544937, "null": 0.6659916929566059}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10468.json
new file mode 100644
index 00000000000..e3032baefd2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10468.json
@@ -0,0 +1 @@
+{"BEOVU": 101.652823916932, "COMIRNATY": 0.0808922164544129, "EYLEA": 24.197769892587285, "INTRONA": 31.436448157819083, "PEGASYS": 36.38676998837902, "PEGINTERFERON": 64.12214875453809, "PEGINTRON": 94.25267125992168, "VAXZEVRIA": 0.1513622858222856, "null": 0.3224551191653643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10469.json
new file mode 100644
index 00000000000..1ac8fbdcc29
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10469.json
@@ -0,0 +1 @@
+{"null": 0.3298069902451951}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1047.json
index 765ac575561..7876e227e96 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1047.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1047.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 3.199922434612168, "COVID19": 1.2940704344447702, "KYMRIAH": 50.14012708155608, "VAXZEVRIA": 3.1328476950571247}
\ No newline at end of file
+{"null": 1.7192814246570212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10470.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10470.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10471.json
new file mode 100644
index 00000000000..03a45551a6f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10471.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.129114088644366, "APIDRA": 3.028321620644721, "AVANDIA": 1.2472562313021265, "AVASTIN": 2.7184359044385493, "BEOVU": 56.89751892785781, "BRILIQUE": 3.503909727910103, "BROLUCIZUMAB": 50.36075305203824, "CICLOSPORIN": 1.6147944114494484, "CLOPIDOGREL": 3.538563226128125, "COMIRNATY": 0.2056347460913891, "CYTARABINE": 1.551144111855305, "ELIQUIS": 4.070245309094513, "EVISTA": 9.03686149142727, "EYLEA": 76.52883799662915, "HUMALOG": 5.029519128158021, "INSULIN": 1.470445759204693, "INTRONA": 33.485233373825295, "LANTUS": 6.27677733383914, "NEXAVAR": 1.1788640428145143, "NOVORAPID": 1.4702249208847478, "PEGASYS": 8.884964568376708, "PEGINTERFERON": 8.071470233191773, "PEGINTRON": 24.14369905346032, "PLAVIX": 8.53118637722105, "RIBAVIRIN": 1.6614280027412878, "SPIKEVAX": 0.1234255124243695, "SPRYCEL": 2.575983980954837, "SUTENT": 0.2367074873226701, "TOZINAMERAN": 0.1621294642342235, "TRULICITY": 1.730204429891185, "VAXZEVRIA": 0.1605169922495864, "VFEND": 6.022153089526001, "VIAGRA": 8.816283129497826, "null": 0.7225529932772815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10472.json
new file mode 100644
index 00000000000..566b1dfa67a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10472.json
@@ -0,0 +1 @@
+{"null": 0.6745724308500136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10473.json
new file mode 100644
index 00000000000..9c21761c4fe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10473.json
@@ -0,0 +1 @@
+{"null": 0.5610331033905649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10474.json
new file mode 100644
index 00000000000..277b427234a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10474.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1398415559265132, "HUMALOG": 9.023831652987186, "JETREA": 1680.568291975413, "LANTUS": 6.2988308178496215, "PEGASYS": 2.335385519740654, "VAXZEVRIA": 0.2100877065251344, "null": 0.943777988522767}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10475.json
new file mode 100644
index 00000000000..73ce94c7716
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10475.json
@@ -0,0 +1 @@
+{"BEOVU": 384.2242388195816, "COMIRNATY": 0.231416917259222, "EYLEA": 23.228933000531068, "PEGASYS": 3.854736152723765, "PEGINTERFERON": 87.61303857610712, "PEGINTRON": 22.977075856824367, "VAXZEVRIA": 0.2158232924351446, "null": 0.4344724965356093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10476.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10476.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10477.json
new file mode 100644
index 00000000000..2d0ef8f2bab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10477.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3680159453671393, "SPIKEVAX": 0.8087792516607463, "TOZINAMERAN": 6.998478303758776, "VAXZEVRIA": 8.88023104873806}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10478.json
new file mode 100644
index 00000000000..6e3eb854582
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10478.json
@@ -0,0 +1 @@
+{"EYLEA": 130.0874016000184, "null": 0.2862409193252258}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10479.json
new file mode 100644
index 00000000000..8f0ce7b3d46
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10479.json
@@ -0,0 +1 @@
+{"BEOVU": 3097.1492635585246, "BROLUCIZUMAB": 1008.7292465087723, "null": 0.3015661597751082}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1048.json
index 3cef8a5e528..45845a2148c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1048.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1048.json
@@ -1 +1 @@
-{"BARICITINIB": 5597.03623549758}
\ No newline at end of file
+{"ANAKINRA": 99.00280369832056, "ARAVA": 2.4766110911144734, "null": 0.6475402268229129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10480.json
new file mode 100644
index 00000000000..fe4914cd853
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10480.json
@@ -0,0 +1 @@
+{"AVASTIN": 10.128870024310418, "BEOVU": 208.7182510189823, "BRAFTOVI": 40.14540824223618, "BROLUCIZUMAB": 250.10108620946292, "COMIRNATY": 0.2128693102304361, "EYLEA": 120.5495704471347, "JETREA": 295.54086089338927, "LANTUS": 1.8841751816313608, "null": 0.7597384372759275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10481.json
new file mode 100644
index 00000000000..2eab4be67c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10481.json
@@ -0,0 +1 @@
+{"null": 1.27627354505167}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10482.json
new file mode 100644
index 00000000000..6e61f079902
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10482.json
@@ -0,0 +1 @@
+{"BEOVU": 505.3975975475827, "null": 5.208308729976399}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10483.json
new file mode 100644
index 00000000000..85fcd54570f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10483.json
@@ -0,0 +1 @@
+{"BEOVU": 154.33354710152312, "BROLUCIZUMAB": 366.5736579907837, "EYLEA": 2407.0856342317343, "null": 0.1480917854307774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10484.json
new file mode 100644
index 00000000000..0a1ae0b65e6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10484.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5057018808544654, "EYLEA": 57.25718063344213, "null": 0.9390831921603298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10485.json
new file mode 100644
index 00000000000..149c957f285
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10485.json
@@ -0,0 +1 @@
+{"null": 2.276080430552108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10486.json
new file mode 100644
index 00000000000..d07689a57a9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10486.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 109.2740254531544, "EYLEA": 140.03188575034645, "null": 0.3697163517313966}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10487.json
new file mode 100644
index 00000000000..e843a8fc3e6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10487.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5110193354651107, "EYLEA": 36.77513999591394, "HUMALOG": 5.771815404008092, "JETREA": 547.28167322381, "LUXTURNA": 709.9379170442716, "PEGASYS": 2.89043483767409, "SPIKEVAX": 0.2788299679522548, "TOZINAMERAN": 0.95714921292823, "VAXZEVRIA": 0.408541856969409, "VIAGRA": 12.81989975830042, "VOTRIENT": 9.127293484818644, "ZOSTAVAX": 6.911935323526174, "null": 0.8009397186095403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10488.json
new file mode 100644
index 00000000000..d4bea763f44
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10488.json
@@ -0,0 +1 @@
+{"EYLEA": 334.7205018796414}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10489.json
new file mode 100644
index 00000000000..33c8884b2a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10489.json
@@ -0,0 +1 @@
+{"ARAVA": 1.3456255904420185, "EFAVIRENZ": 68.61216477661677, "HUMIRA": 30.249776185190637, "VIGABATRIN": 363.0742873900012, "null": 1.2935185751943523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1049.json
index 01b7fb3d4a8..21ee463d824 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1049.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1049.json
@@ -1 +1 @@
-{"null": 1.403295159162802}
\ No newline at end of file
+{"APTIVUS": 209.5312950032599, "KEYTRUDA": 4.529578160979906, "NEXAVAR": 8.290245484033543, "OCALIVA": 79.22118340654633, "PEGASYS": 2.097610924178935, "QARZIBA": 262.8945304909362, "null": 0.5980993001555625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10490.json
new file mode 100644
index 00000000000..1786a17dfaf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10490.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2066468070905811, "EYLEA": 29.075074191409005, "VIAGRA": 28.04830552645352, "null": 0.5439966345665105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10491.json
new file mode 100644
index 00000000000..dbcdccd2998
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10491.json
@@ -0,0 +1 @@
+{"AVASTIN": 9.162941672827689, "BEOVU": 1085.3663207639063, "BROLUCIZUMAB": 337.6209236249197, "COMIRNATY": 0.5137437555256974, "EYLEA": 25.032764668497386, "PEGASYS": 1.6329548913627674, "TOPOTECAN": 66.39421643281551, "VAXZEVRIA": 0.1825397866402765, "VIAGRA": 9.724317708831189, "null": 0.6872963754668245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10492.json
new file mode 100644
index 00000000000..472102692aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10492.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.504870824020662, "EVISTA": 47.758186534802206, "PEGASYS": 2.4073594416780324, "PEGINTRON": 5.725431121513322, "SPIKEVAX": 0.6355204509876734, "VAXZEVRIA": 1.3127287602660092, "null": 0.3194759612376068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10493.json
new file mode 100644
index 00000000000..88faf44471e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10493.json
@@ -0,0 +1 @@
+{"BEOVU": 1958.8201216085724, "BROLUCIZUMAB": 1058.3681285443824, "COMIRNATY": 0.0551531896697335, "EYLEA": 39.34327991532334, "TOZINAMERAN": 0.3357139051871738, "null": 1.1906018039433968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10494.json
new file mode 100644
index 00000000000..c07faec3d44
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10494.json
@@ -0,0 +1 @@
+{"BEOVU": 38.83457347859932, "COMIRNATY": 1.491893880586748, "COTELLIC": 12.765318213638976, "ELIQUIS": 0.5075152152285627, "EVISTA": 51.93797886780008, "EYLEA": 13.584451709170647, "FASLODEX": 2.071914513698653, "INTRONA": 15.613812942114516, "LANTUS": 0.8328620910349057, "MEKINIST": 3.3326379020841856, "NEXAVAR": 1.3752686693851064, "PEGASYS": 1.4726458510556122, "PEGINTERFERON": 3.3561024058885565, "PEGINTRON": 11.679088892669055, "RINVOQ": 5.782430950692493, "SILDENAFIL": 5.921573342203902, "SPIKEVAX": 0.8447785157880198, "STELARA": 0.7473991474251326, "TOZINAMERAN": 1.774519782633667, "VAXZEVRIA": 1.8414829663548733, "VIAGRA": 10.096454587330792, "XELJANZ": 0.673861252009972, "ZOSTAVAX": 0.8415994863775919, "null": 0.3885889896632601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10495.json
new file mode 100644
index 00000000000..192f4f26efb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10495.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.292055134441792, "EVISTA": 110.84675997302188, "NEXAVAR": 3.3760254092020348, "PEGASYS": 3.852955619705516, "PEGINTRON": 9.97927039068865, "SPIKEVAX": 0.5793187629233219, "VAXZEVRIA": 1.3246771445003769, "VIAGRA": 11.930644124753902, "null": 0.3786496247812099}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10496.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10496.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10497.json
new file mode 100644
index 00000000000..628cff9a1ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10497.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": 13.564566377877211}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10498.json
new file mode 100644
index 00000000000..de55d62633b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10498.json
@@ -0,0 +1 @@
+{"BEOVU": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10499.json
new file mode 100644
index 00000000000..6cb35fad31d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10499.json
@@ -0,0 +1 @@
+{"ABATACEPT": 7.381688407250523, "ADALIMUMAB": 25.66693133718008, "CICLOSPORIN": 7.953734482482344, "COMIRNATY": 0.0877457039664412, "ENBREL": 9.633753311094074, "GANCICLOVIR": 56.1019253052003, "PEGASYS": 3.638104008018494, "PEGINTRON": 4.925367400351732, "null": 0.2777323097463512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/105.json
index f687fd82dc4..6ebfdf73768 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/105.json
@@ -1 +1 @@
-{"ZOSTAVAX": 489.9709026207715}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1050.json
index 6da6e667bec..7f0c8c6ca30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1050.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1050.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"null": 1.9473445026686216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10500.json
new file mode 100644
index 00000000000..f64dab7cb17
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10500.json
@@ -0,0 +1 @@
+{"UMECLIDINIUM": 926.4739005449812, "VIAGRA": 70.52044323766061, "null": 0.6341789296864849}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10501.json
new file mode 100644
index 00000000000..11dea922652
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10501.json
@@ -0,0 +1 @@
+{"BUSULFAN": 479.0125204868015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10502.json
new file mode 100644
index 00000000000..990535eaff8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10502.json
@@ -0,0 +1 @@
+{"TOPOTECAN": 3095.191333454762, "null": 0.5234282361212452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10503.json
new file mode 100644
index 00000000000..66d693a98f3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10503.json
@@ -0,0 +1 @@
+{"JETREA": 1513.6379296903715, "VIGABATRIN": 2065.285641059615, "null": 2.5038413653903167}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10504.json
new file mode 100644
index 00000000000..f1bd0acfaad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10504.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10505.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10505.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10506.json
new file mode 100644
index 00000000000..f92b7bbefcd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10506.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10507.json
new file mode 100644
index 00000000000..013f7ee1dea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10507.json
@@ -0,0 +1 @@
+{"null": 1.2362229223707628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10508.json
new file mode 100644
index 00000000000..49492e7bd67
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10508.json
@@ -0,0 +1 @@
+{"ANTHRACYCLINES": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10509.json
new file mode 100644
index 00000000000..9cc521fcbb4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10509.json
@@ -0,0 +1 @@
+{"null": 2.755514165265037}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1051.json
index b0071345a64..2d5c6dd4520 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1051.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1051.json
@@ -1 +1 @@
-{"null": 4.060989426796331}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10510.json
new file mode 100644
index 00000000000..67efd886a83
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10510.json
@@ -0,0 +1 @@
+{"LANTUS": 20.9942897144762, "null": 0.6487643009059564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10511.json
new file mode 100644
index 00000000000..65b0fa474f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10511.json
@@ -0,0 +1 @@
+{"null": 1.7424497548446465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10512.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10512.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10513.json
new file mode 100644
index 00000000000..04d446d71ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10513.json
@@ -0,0 +1 @@
+{"null": 0.489587685703479}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10514.json
new file mode 100644
index 00000000000..f0ad5b64d03
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10514.json
@@ -0,0 +1 @@
+{"CANNABIDIOL": 2835.8261528496346}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10515.json
new file mode 100644
index 00000000000..6b63f0a8ed1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10515.json
@@ -0,0 +1 @@
+{"KEPPRA": 13.163256598537629, "TRUVADA": 5.59164034990184, "null": 3.8478079667303136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10516.json
new file mode 100644
index 00000000000..eef80547ce1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10516.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5559292800504115, "VAXZEVRIA": 0.1931106815719682, "null": 1.6928034197335546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10517.json
new file mode 100644
index 00000000000..84f2423cde9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10517.json
@@ -0,0 +1 @@
+{"SILODOSIN": 777.6218048306735, "SILODYX": 2112.8729472760488, "UROREC": 2970.1814121982547, "null": 1.8469769415543489}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10518.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10518.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10519.json
new file mode 100644
index 00000000000..114085192f5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10519.json
@@ -0,0 +1 @@
+{"null": 0.7705428455000378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1052.json
index c348fd39613..85f4041c5e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1052.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1052.json
@@ -1 +1 @@
-{"BUSULFAN": 190.06893961592425, "DOXORUBICIN": 185.46856782293065, "SOMATROPIN": 128.62945455890866, "null": 1.1410188114864512}
\ No newline at end of file
+{"SPIKEVAX": 28.53033660629104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10520.json
new file mode 100644
index 00000000000..aacada42562
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10520.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 5.4751955530122345, "null": 3.7908698054073326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10521.json
new file mode 100644
index 00000000000..cbed33b657c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10521.json
@@ -0,0 +1 @@
+{"APREMILAST": 19.220423831318243, "BRILIQUE": 6.062882995713654, "BUDESONIDE": 1.337033048659945, "CLOPIDOGREL": 18.075791158665453, "COMIRNATY": 0.0355054788225432, "EFIENT": 27.170701029616268, "ELIQUIS": 6.3577309048513495, "ENOXAPARIN": 107.98889786794795, "PLAVIX": 11.3300107677197, "XARELTO": 10.66453769730496, "null": 3.02300056348654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10522.json
new file mode 100644
index 00000000000..4b592f8d358
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10522.json
@@ -0,0 +1 @@
+{"APIXABAN": 1.757175440609199, "BUDESONIDE": 1.1452964694959689, "CLOPIDOGREL": 17.70716166016248, "EFIENT": 28.871328669811827, "ELIQUIS": 5.045084565701544, "ENOXAPARIN": 34.67923751944798, "INTEGRILIN": 163.9798936559638, "PLAVIX": 16.622110260283872, "XARELTO": 13.873805144048994, "null": 3.3708096844275155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10523.json
new file mode 100644
index 00000000000..b0c6cdc0fc3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10523.json
@@ -0,0 +1 @@
+{"ADCIRCA": 103.74743064531977, "NEXAVAR": 22.06095574041033, "STIVARGA": 16.280993968272302, "null": 0.1862161389768827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10524.json
new file mode 100644
index 00000000000..f98727b5f2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10524.json
@@ -0,0 +1 @@
+{"null": 0.6150315419721749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10525.json
new file mode 100644
index 00000000000..37f565f86fc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10525.json
@@ -0,0 +1 @@
+{"null": 0.8145643285262828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10526.json
new file mode 100644
index 00000000000..4e8aa3433db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10526.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8798573920970705, "null": 1.5687787135911493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10527.json
new file mode 100644
index 00000000000..9469134ead8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10527.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.626573297646525, "VAXZEVRIA": 1.9178097868560475, "null": 0.3773868520040616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10528.json
new file mode 100644
index 00000000000..d625df1095f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10528.json
@@ -0,0 +1 @@
+{"AVAMYS": 94.12050615838189, "BUDESONIDE": 37.97060983587777, "DULOXETINE": 368.2123052702108, "MEPOLIZUMAB": 165.7006865641942, "NUCALA": 13.901269795794256, "null": 0.271889124138904}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10529.json
new file mode 100644
index 00000000000..cd4dc692ec8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10529.json
@@ -0,0 +1 @@
+{"AIMOVIG": 5.032125993473026, "CHAMPIX": 4.025814187258132, "CICLOSPORIN": 3.157751558221252, "COMIRNATY": 0.1926471514169512, "DULOXETINE": 34.84893835710709, "ERENUMAB": 84.96753267042453, "SPIKEVAX": 0.2034891192214085, "null": 2.2454823445576086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1053.json
index e88e42e5429..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1053.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1053.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 27.086967440957697, "null": 1.6132096345615383}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10530.json
new file mode 100644
index 00000000000..c23dfc88d1a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10530.json
@@ -0,0 +1 @@
+{"null": 1.122026655990208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10531.json
new file mode 100644
index 00000000000..88aaa245d33
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10531.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": 41.50299562260962, "null": 2.082075459237711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10532.json
new file mode 100644
index 00000000000..96639dd8a53
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10532.json
@@ -0,0 +1 @@
+{"METHOTREXATE": 595.147822894265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10533.json
new file mode 100644
index 00000000000..58e74704b03
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10533.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.3061001670890864, "ABILIFY": 2.3289161958441773, "ABIRATERONE": 27.94208360278053, "ACTOS": 2.356739891110976, "ACTRAPID": 1.222535869209162, "ADENURIC": 5.020321492051533, "AERIUS": 4.118021162239319, "AFINITOR": 0.1630251198160274, "ALIMTA": 0.3642252882147893, "ALLI": 17.955012444715173, "APIDRA": 0.4823942193944355, "APROVEL": 3.719814650151701, "ARAVA": 0.0223077978669764, "ARIPIPRAZOLE": 1.2981688412210677, "ATAZANAVIR": 1.399884776198714, "ATRIPLA": 0.2293605361187052, "AUBAGIO": 0.1640901365999173, "AVANDIA": 0.1518364726671542, "AVASTIN": 0.3912554958960088, "AVONEX": 3.1727553854225774, "BARACLUDE": 1.25802137483908, "BENZODIAZEPINE": 7.114819133205719, "BIKTARVY": 0.9758341692191884, "BRAFTOVI": 1.965340398575522, "BRILIQUE": 4.0125640447204844, "BRINTELLIX": 0.4343917508673119, "BUDESONIDE": 0.2058206836193347, "BUPRENORPHINE": 1.181292714007211, "BYDUREON": 0.2207030511040715, "CABOMETYX": 0.6709428837014395, "CANCIDAS": 1.1405029075635182, "CELECOXIB": 0.9063803297781796, "CELLCEPT": 0.8703299782233669, "CHAMPIX": 0.2201575125668378, "CICLOSPORIN": 3.3508372073967547, "CLOPIDOGREL": 0.8860991970228632, "COAPROVEL": 2.5437810653694246, "COMBIVIR": 1.3689638220536138, "COMIRNATY": 0.0698722206545844, "COMTAN": 5.59982229076503, "COMTESS": 10.68367494008711, "COTELLIC": 5.010526842130283, "CRIXIVAN": 1.7203077304974577, "CUBICIN": 29.34515103572772, "CYMBALTA": 0.658975880747963, "DABRAFENIB": 2.4133314712281444, "DACLATASVIR": 2.1838001674814382, "DAPTOMYCIN": 9.308087919250143, "DESCOVY": 1.833067745863858, "DEXAMETHASONE": 0.7935336989040181, "DULOXETINE": 2.136868535775965, "EBIXA": 1.868713641994694, "ELIQUIS": 0.1533039249611454, "EMTRICITABINE": 1.792111931505044, "ENTACAPONE": 3.907979611635122, "ENTECAVIR": 3.788695308583685, "ENTRESTO": 0.6996664313673588, "ESOMEPRAZOLE": 7.046750182093179, "EVISTA": 0.4661984176677295, "EXFORGE": 0.8104745538184732, "EXVIERA": 1.8247668453879329, "FASLODEX": 0.2032561315883917, "FEBUXOSTAT": 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"PEGINTRON": 1.438044181885073, "PEMBROLIZUMAB": 0.4951400439694192, "PLAVIX": 1.1774290164444738, "POSACONAZOLE": 4.701720694925154, "PREGABALIN": 3.391803948352101, "PROPRANOLOL": 2.0982165674416087, "RANEXA": 3.551616840388013, "RANOLAZINE": 4.685660491757384, "RAPAMUNE": 0.8250043865884021, "REYATAZ": 1.7496726398784666, "RINVOQ": 0.6346626572481766, "RISPERIDONE": 2.862704163174849, "RIVAROXABAN": 2.11602140541644, "SIFROL": 2.720041660178831, "SILDENAFIL": 0.513058095341352, "SIMPONI": 0.1292861231698383, "SOLIRIS": 0.2992252742283184, "SOVALDI": 1.2478141442424062, "SPIKEVAX": 0.0844843844786591, "SPIRONOLACTONE": 0.8046935278077103, "SPRYCEL": 0.4253731482514739, "STALEVO": 2.870390291627024, "STELARA": 0.175974574678638, "STIVARGA": 0.5447129459708443, "STRIBILD": 0.4058264114193364, "SUBOXONE": 0.6039205748293339, "SUFENTANIL": 1.127654624196125, "SUTENT": 0.4323910696717108, "SYCREST": 7.34031382418971, "TAGRISSO": 0.6909769314775835, "TAMIFLU": 3.450854041752684, "TASIGNA": 0.5808602038643624, "TELMISARTAN": 2.479783272090896, "TESTOSTERONE": 1.677814070659341, "TICAGRELOR": 12.100416845817044, "TIVICAY": 1.4099638075115313, "TOZINAMERAN": 0.1400533531593665, "TRABECTEDIN": 36.30981724335528, "TRACLEER": 0.1721134815837966, "TRIUMEQ": 2.276912589685794, "TRUVADA": 0.2471519940802636, "VAXZEVRIA": 0.029796931465507, "VFEND": 3.031479370740858, "VIAGRA": 0.4564120626930279, "VICTOZA": 0.492912010646746, "VILDAGLIPTIN": 3.732917095042711, "VIMPAT": 1.1478598294588809, "VIREAD": 1.133650374579738, "VORICONAZOLE": 2.861615606029979, "VOTRIENT": 0.2015120541288232, "XEPLION": 11.90145791408296, "XOLAIR": 0.1192898898003846, "XTANDI": 0.1843191442739237, "YONDELIS": 49.58194982393093, "ZOSTAVAX": 0.1158871289427491, "ZYPADHERA": 0.5329809571372522, "ZYPREXA": 6.191222633861633, "ZYTIGA": 11.56432057170765, "null": 3.244381289549749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10534.json
new file mode 100644
index 00000000000..ce2ea68c7f5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10534.json
@@ -0,0 +1 @@
+{"VOTRIENT": 48.498195511699386, "null": 1.247995696386685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10535.json
new file mode 100644
index 00000000000..5be285b64fd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10535.json
@@ -0,0 +1 @@
+{"JETREA": 1503.9515480011232, "null": 0.2446933670843351}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10536.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10536.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10537.json
new file mode 100644
index 00000000000..6cf1cbff9f3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10537.json
@@ -0,0 +1 @@
+{"ABILIFY": 2169.1921145904967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10538.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10538.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10539.json
new file mode 100644
index 00000000000..08859f864b5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10539.json
@@ -0,0 +1 @@
+{"ARAVA": 0.7956635137328625, "COMIRNATY": 2.8690511326291657, "COMTAN": 14.523453796676922, "COSENTYX": 3.4168401051092285, "ELIQUIS": 0.6865113453634104, "ENTRESTO": 1.8399301374357868, "FASENRA": 4.988184396201542, "FORSTEO": 5.344742168332026, "GARDASIL": 1.7910520726580763, "KEYTRUDA": 2.1512294188501757, "METHOTREXATE": 2.5640638288053124, "RINVOQ": 5.935076745649219, "SIMPONI": 5.4111503365378, "SPIKEVAX": 1.2938986072809937, "STELARA": 1.0106990347865057, "TOZINAMERAN": 0.4492622714358592, "VAXZEVRIA": 0.598119086005641, "XOLAIR": 1.2976692911900338, "null": 0.3426138181440064}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1054.json
index 9a9fd5d6e57..c3d902ecb64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1054.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1054.json
@@ -1 +1 @@
-{"COVID19": 4.083143474442781}
\ No newline at end of file
+{"VFEND": 54.06000265178909, "null": 0.5911558561831666}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10540.json
new file mode 100644
index 00000000000..bced0f26a13
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10540.json
@@ -0,0 +1 @@
+{"ABATACEPT": 13.65517488085094, "ADALIMUMAB": 37.429979790053125, "AMINOSALICYLIC": 5.271767300810192, "APREMILAST": 156.28610650017237, "ARAVA": 31.356341581121704, "CIMZIA": 12.879379333162904, "COMIRNATY": 0.0619290141829816, "COSENTYX": 6.045326451066462, "RITUXIMAB": 1.847920755997588, "null": 0.0209928938531432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10541.json
new file mode 100644
index 00000000000..c7bbe0dda16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10541.json
@@ -0,0 +1 @@
+{"null": 1.2052203392349996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10542.json
new file mode 100644
index 00000000000..e7f81565344
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10542.json
@@ -0,0 +1 @@
+{"ABACAVIR": 13.68568399991304, "ABATACEPT": 6.101438062329308, "ABILIFY": 0.1692504715899118, "ACLASTA": 6.655821182683525, "ADALIMUMAB": 7.22940361909431, "ADCIRCA": 0.625357063812088, "AIMOVIG": 0.2768425547978146, "ALIMTA": 0.1327574899030386, "ANAKINRA": 14.801589004658808, "APIDRA": 0.2255076894179672, "APREMILAST": 7.7303399343699954, "APREPITANT": 0.3554885101279692, "ARAVA": 26.074845031587152, "ATRIPLA": 0.08004290017729, "AUBAGIO": 0.1262718320536688, "AZATHIOPRINE": 1.2211450947704083, "BENLYSTA": 0.6381770964725064, "BONVIVA": 0.4096649970052748, "BUDESONIDE": 0.2864265531089302, "BYDUREON": 0.1575218846381554, "BYETTA": 0.1610600023189748, "CELECOXIB": 1.4179978667143336, "CELLCEPT": 0.6879049009527377, "CERTOLIZUMAB": 9.303008597753555, "CHAMPIX": 0.0865875421724432, "CICLOSPORIN": 0.7297200127698316, "CIMZIA": 19.281644836320517, "COMIRNATY": 0.2183808917045972, "COSENTYX": 2.483252149875841, "CYMBALTA": 0.984824135391011, "DACLIZUMAB": 23.010481461671752, "DULOXETINE": 0.4598672601507173, "ELIQUIS": 0.2559348011133768, "ENBREL": 24.088334555396862, "ENTRESTO": 0.1148939418007942, "ENTYVIO": 0.2240037987296073, "ERELZI": 13.17249183248548, "ESBRIET": 0.1616847174432888, "ESOMEPRAZOLE": 0.4907712339478493, "ETANERCEPT": 5.573465511015581, "EVENITY": 0.4892094066032381, "FASENRA": 0.1987439546232781, "FASLODEX": 0.0890744179209649, "FENTANYL": 0.1380710913364814, "FORSTEO": 0.2891692038540357, "GARDASIL": 0.28888409738989, "GOLIMUMAB": 6.935613258051929, "HERCEPTIN": 0.2361001584835883, "HIZENTRA": 0.5448712535744649, "HUMALOG": 0.287524860577991, "HUMIRA": 9.134133762900312, "IBRANCE": 0.1026544987664651, "IBUPROFEN": 0.157840022291672, "INLYTA": 0.129800422210507, "INSULIN": 0.2146637985043813, "IPILIMUMAB": 0.3215369145697495, "JANSSEN": 1.6827038984586096, "JANUMET": 0.1499840232201267, "JANUVIA": 0.4398765825586197, "JARDIANCE": 0.0546944746798139, "KEVZARA": 11.266127632936591, "KEYTRUDA": 0.8277159681811318, "LANTUS": 0.2545485549727169, "LEFLUNOMIDE": 13.246104118282505, "LEMTRADA": 0.1898539697199769, "LEVEMIR": 0.4984918606306017, "LEVOFLOXACIN": 0.1048773221799018, "LYRICA": 0.4282074948265485, "MABTHERA": 0.4666046411784122, "MEPOLIZUMAB": 0.2451304629036938, "METFORMIN": 1.6344636288171668, "METHOTREXATE": 8.408070142072477, "MICARDIS": 0.1486154766101499, "MODERNA": 0.0704779632441917, "NEXAVAR": 0.0668604713363657, "NUCALA": 0.1962752010974719, "OFEV": 0.3927154392996848, "OMALIZUMAB": 0.1801700122462329, "OPDIVO": 0.4293876420587295, "OPSUMIT": 0.1218985996888914, "ORENCIA": 10.99652474063949, "PANTOPRAZOLE": 0.8218663031696085, "PEGASYS": 0.3938321049734447, "PEGINTERFERON": 0.1163388117398625, "PEGINTRON": 0.5286776415691408, "PEMBROLIZUMAB": 0.683024592973471, "REBETOL": 0.4264519111012721, "REMICADE": 2.548970405139753, "RINVOQ": 7.010658667884783, "RITUXIMAB": 2.359531260077865, "ROACTEMRA": 3.8882814236022334, "SHINGRIX": 0.6486699879066951, "SILDENAFIL": 0.357185108354741, "SIMPONI": 11.58805494083403, "SOLIRIS": 0.0957167456006467, "SOVALDI": 0.5768602663628316, "SPIKEVAX": 0.1425917494790405, "STELARA": 0.5204658765000933, "SUBOXONE": 0.0842794727564978, "SUTENT": 0.0301088350409116, "TASIGNA": 0.122027916255449, "TOCILIZUMAB": 1.9536873083806556, "TOFACITINIB": 4.11645173799976, "TOVIAZ": 0.3271499318855923, "TOZINAMERAN": 0.4251828264925806, "TRELEGY": 0.2750349780397671, "TREMFYA": 0.7774744566825471, "TRULICITY": 0.099229984520104, "TRUVADA": 0.0524071831856845, "TWINRIX": 0.4133382808862846, "VAXZEVRIA": 0.0936947719667324, "VFEND": 0.1228259071065143, "VIAGRA": 0.226414112929835, "XELJANZ": 9.682948023637778, "XOLAIR": 0.3898526490001981, "ZOSTAVAX": 0.6136187553960322, "null": 0.214446801279267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10543.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10543.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10544.json
new file mode 100644
index 00000000000..dd5e2eec71d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10544.json
@@ -0,0 +1 @@
+{"ARAVA": 2.8822192279413748, "COMIRNATY": 1.044402168031378, "SIMPONI": 11.108732282452252, "SPIKEVAX": 0.2855781837478822, "TOZINAMERAN": 0.8885414639541501, "XELJANZ": 4.314249188528619, "null": 0.4437507685624521}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10545.json
new file mode 100644
index 00000000000..9b6c79cb36f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10545.json
@@ -0,0 +1 @@
+{"ARAVA": 54.05395257023845, "CICLOSPORIN": 16.03716928016131, "CIMZIA": 32.11349524032114, "ENBREL": 17.445539103306672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10546.json
new file mode 100644
index 00000000000..9de1b1b62fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10546.json
@@ -0,0 +1 @@
+{"ABATACEPT": 13.035815573804806, "ADALIMUMAB": 24.49737391704179, "ANAKINRA": 19.17093532128361, "APREMILAST": 69.50122848091762, "ARAVA": 57.67830202675936, "BUDESONIDE": 1.8605500500379828, "CELLCEPT": 0.8639694725223881, "CICLOSPORIN": 0.8857270122314685, "CIMZIA": 3.0030154392470445, "COMIRNATY": 0.01571626349439, "COSENTYX": 2.986512725010092, "ENBREL": 7.449593170170464, "HUMIRA": 6.006983877141806, "METHOTREXATE": 2.505831804615381, "RITUXIMAB": 2.053813475488952, "null": 0.025420113550909}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10547.json
new file mode 100644
index 00000000000..b1e9232177a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10547.json
@@ -0,0 +1 @@
+{"ABATACEPT": 15.615580203277398, "ADALIMUMAB": 9.477204621579125, "ARAVA": 7.327788556006872, "ENBREL": 26.516109430127504, "XELJANZ": 15.223563629562108, "null": 0.376169405529513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10548.json
new file mode 100644
index 00000000000..6cc0aea1106
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10548.json
@@ -0,0 +1 @@
+{"SIMPONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10549.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10549.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1055.json
index 99b4fd02ef8..0a148859003 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1055.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1055.json
@@ -1 +1 @@
-{"ABASAGLAR": 67.53836703459412, "ACTRAPID": 7.130757524787525, "ADENURIC": 4.063265812431441, "AFINITOR": 1.151328107063778, "ALPELISIB": 9.06533303656946, "APIDRA": 31.09160162049538, "ARIPIPRAZOLE": 1.334328130375008, "BYDUREON": 7.297975957081946, "BYETTA": 4.729786886055354, "DULAGLUTIDE": 19.629489300989093, "EMPAGLIFLOZIN": 4.100697428310465, "EUCREAS": 4.7680095273092045, "FIASP": 48.16387219679721, "FORXIGA": 4.774778028303274, "GALVUS": 4.378626138673745, "GLUCAGON": 6.807152851030573, "HUMALOG": 41.51751871314652, "INSULATARD": 19.79542384290868, "INSULIN": 21.827265417373628, "INSUMAN": 32.15073150275138, "ISOPHANE": 20.3566449972741, "JANUMET": 12.312648526595048, "JANUVIA": 7.728435781967854, "JARDIANCE": 7.688193206084235, "LANTUS": 21.267595568300774, "LEVEMIR": 15.898193397272356, "LIPROLOG": 53.4575286452238, "LYUMJEV": 35.67015555704494, "MIXTARD": 21.036016878035117, "NOVORAPID": 39.75551157948605, "OZEMPIC": 10.328735218500436, "TOUJEO": 31.597072799389988, "TRESIBA": 24.78087972701366, "TRULICITY": 10.467575420659744, "VICTOZA": 4.417699145759358}
\ No newline at end of file
+{"ALEMTUZUMAB": 14.969159915456345, "AMIKACIN": 18.113661635648967, "ASPARAGINASE": 46.20120275181276, "AZACITIDINE": 10.788052278201825, "AZATHIOPRINE": 4.296953895506367, "BASILIXIMAB": 24.4099178951502, "BLINATUMOMAB": 42.72199471662792, "BORTEZOMIB": 6.431472475851303, "BUDESONIDE": 6.0440470551298615, "BUSULFAN": 23.45629891576169, "CANCIDAS": 36.52320069456084, "CARMUSTINE": 17.246744755243064, "CASPOFUNGIN": 123.17096430585688, "CELLCEPT": 10.019641054440182, "CICLOSPORIN": 23.20960903153845, "CIMZIA": 1.3179539860195677, "CLADRIBINE": 23.72396171552516, "CLOFARABINE": 31.13863881843494, "CRESEMBA": 37.95264855299348, "CYTARABINE": 15.935425382432026, "DEXAMETHASONE": 10.386760328861705, "DOXORUBICIN": 5.890724589947423, "ESOMEPRAZOLE": 4.914861960065954, "GANCICLOVIR": 6.04004687555517, "HYDROCORTISONE": 4.03508640411214, "IBRUTINIB": 55.08954281720174, "JAKAVI": 4.387693849812149, "LEVOFLOXACIN": 2.2400627302207523, "MEPOLIZUMAB": 5.674142225687422, "METHOTREXATE": 3.069323690797092, "MICAFUNGIN": 77.7193910044586, "MYCOPHENOLATE": 22.9935490410116, "NOXAFIL": 30.32686296215917, "OMALIZUMAB": 1.3266701772082985, "OPDIVO": 1.4262668994433956, "POSACONAZOLE": 30.36901757396796, "RITUXIMAB": 4.614899114539711, "ROACTEMRA": 3.69058786739076, "SOLIRIS": 3.880147154559228, "TACROLIMUS": 13.91952464524402, "TAMIFLU": 1.5444390594965158, "VFEND": 38.75906954946362, "VORICONAZOLE": 57.90992094083037, "XOLAIR": 1.2211064904199287, "YESCARTA": 5.149610333616589, "null": 0.3420395866368706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10550.json
new file mode 100644
index 00000000000..6b0a7abf5cc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10550.json
@@ -0,0 +1 @@
+{"ABATACEPT": 12.427355017890552, "ADALIMUMAB": 4.629829863930944, "ARAVA": 34.1196640099793, "CICLOSPORIN": 3.73864900382675, "CIMZIA": 1.9557908764919665, "COSENTYX": 5.593564588302574, "ENBREL": 69.33143999834049, "LEFLUNOMIDE": 22.908391574775177, "METHOTREXATE": 17.943195945349952, "ROACTEMRA": 15.54361075446031, "XELJANZ": 3.206025865469213, "null": 0.0805759251684929}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10551.json
new file mode 100644
index 00000000000..faa6172baa6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10551.json
@@ -0,0 +1 @@
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10552.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10552.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10553.json
new file mode 100644
index 00000000000..ecc5be39470
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10553.json
@@ -0,0 +1 @@
+{"SIMPONI": 69.3848263262437, "null": 0.6671588520219112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10554.json
new file mode 100644
index 00000000000..e7205867910
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10554.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 44.776707830639154, "AVAMYS": 25.89613634342738, "BAQSIMI": 681.5825439883189, "COMIRNATY": 0.7477634086615265, "COSENTYX": 2.054292359822527, "SPIKEVAX": 0.735929540616869, "SUTENT": 1.5855283928721309, "TOZINAMERAN": 0.7895222996280428, "VAXZEVRIA": 0.692747686873816, "null": 1.442891687916508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10555.json
new file mode 100644
index 00000000000..0156d9673c7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10555.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 1.0673034656250826, "AIMOVIG": 0.7035283863185071, "ANORO": 1.642813767920711, "AVAMYS": 4.125751884008887, "BENLYSTA": 2.836004513993525, "BUDESONIDE": 0.4641846268263307, "CHAMPIX": 0.6301919203722404, "CIMZIA": 0.2090504234772471, "COMIRNATY": 1.3621036433178055, "COSENTYX": 2.094240818275633, "CYMBALTA": 0.2816434917382153, "DEXAMETHASONE": 0.4436452270413805, "ENTYVIO": 1.0183463911827553, "EXFORGE": 1.2733096845663208, "FASENRA": 4.304935102377101, "GARDASIL": 1.0031865481629754, "HIZENTRA": 1.1296223045380185, "HUMALOG": 0.2933031329541152, "INFANRIX": 3.098262815554304, "JANUVIA": 0.6037877486617185, "KEPPRA": 0.5760136032460244, "LANTUS": 0.3145799085246167, "LEVOFLOXACIN": 0.4696682692159295, "MEPOLIZUMAB": 7.535323452131012, "METHOTREXATE": 1.7450020562706758, "MICARDIS": 1.1545985418892246, "MMRVAXPRO": 5.836410905507463, "MODERNA": 0.6787967715628911, "NIMENRIX": 3.795879919456345, "NUCALA": 4.079836784001023, "OMALIZUMAB": 1.1168434110251515, "PEGINTRON": 1.1755372333269023, "PRIVIGEN": 1.5912021103572072, "RELVAR": 5.308669703196212, "RINVOQ": 1.1507217378647714, "ROACTEMRA": 0.972635179386108, "ROTATEQ": 3.664601465994487, "SIMPONI": 2.6347781649567064, "SPIKEVAX": 0.6167343476658693, "STELARA": 0.6791902716498086, "SUTENT": 0.1979705370985272, "SYNAGIS": 6.431888217628884, "TOZINAMERAN": 0.3971467579756518, "TRELEGY": 1.4119981255536995, "VAXZEVRIA": 0.9340197596607344, "XELJANZ": 0.4104297707320499, "XOLAIR": 2.456566342968939, "ZOSTAVAX": 1.4933299834603195, "null": 1.385456309075532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10556.json
new file mode 100644
index 00000000000..5fdf69df781
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10556.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 73.9618636737396, "AIMOVIG": 0.7602816044487558, "ANORO": 4.193257042989371, "APIXABAN": 113.38250694989956, "AVAMYS": 20.081912436125357, "BUDESONIDE": 28.36692963226757, "COMIRNATY": 0.2654318550883631, "EFAVIRENZ": 5.643928260125612, "ELIQUIS": 3.076646219833263, "ESOMEPRAZOLE": 5.443084436197959, "FLUTICASONE": 11.770730484843506, "GARDASIL": 1.0269842957852215, "GLYCOPYRRONIUM": 175.31064955010729, "HUMALOG": 2.931640416771561, "KALETRA": 2.2084140933921854, "MEPOLIZUMAB": 1.3797257665565263, "NUCALA": 33.92274209504966, "OMALIZUMAB": 1.3668759059875988, "SIMPONI": 0.7312312295757545, "SPIKEVAX": 0.1301734571867864, "TOZINAMERAN": 0.2026704808342364, "VAXZEVRIA": 0.1169522824732384, "XOLAIR": 1.7830712801293769, "ZOSTAVAX": 13.31298309012348, "null": 0.5830689907731724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10557.json
new file mode 100644
index 00000000000..345f343827e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10557.json
@@ -0,0 +1 @@
+{"null": 2.588873808515698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10558.json
new file mode 100644
index 00000000000..3a8ce374d53
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10558.json
@@ -0,0 +1 @@
+{"null": 0.1806242094116615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10559.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10559.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1056.json
index 1b51aafc86e..a121cce2018 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1056.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1056.json
@@ -1 +1 @@
-{"ABASAGLAR": 19.4507735038502, "ACTOS": 9.874235775866737, "ACTRAPHANE": 13.51894874585776, "ACTRAPID": 8.137205291976633, "APIDRA": 23.342584118340607, "AVANDIA": 1.150762414993023, "BAQSIMI": 49.68690995851325, "BYDUREON": 8.964189560419271, "BYETTA": 10.095433237694916, "DULAGLUTIDE": 30.379715554242512, "ENTRESTO": 1.0883821525915378, "FIASP": 18.604139531717763, "FORXIGA": 2.314089912872085, "GALVUS": 2.4125704585516154, "GLIBENCLAMIDE": 6.087563785479241, "GLUCAGON": 48.71665973824195, "HUMALOG": 61.93563622436351, "INSULATARD": 12.703666656704058, "INSULIN": 21.955601983491853, "INSUMAN": 11.79215330665054, "INVOKANA": 4.678144224379471, "JANUMET": 3.414958301115501, "JANUVIA": 3.6641696805155335, "JARDIANCE": 2.371039581134648, "LANTUS": 32.53224215992403, "LEVEMIR": 29.189055914170343, "LYUMJEV": 12.020110699608816, "MIXTARD": 7.097214063538854, "NOVONORM": 2.889050155628556, "NOVORAPID": 13.582459517961498, "ONGLYZA": 3.954800841711125, "OZEMPIC": 9.544324458130914, "REPAGLINIDE": 5.147961219419824, "RYBELSUS": 2.552622505883805, "SAXENDA": 1.5394577208122853, "SPINRAZA": 1.1347292441570336, "SUTENT": 1.4738670543395054, "TOUJEO": 27.680425353446108, "TRESIBA": 21.925609170856852, "TRULICITY": 7.216397246987838, "VELTASSA": 2.6863316790540908, "VICTOZA": 6.525767397011831}
\ No newline at end of file
+{"null": 0.4985262316515511}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10560.json
new file mode 100644
index 00000000000..d8cf4724861
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10560.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.2432580772005949, "ACLIDINIUM": 1.479722656044943, "AERIUS": 0.9486691236897976, "AFINITOR": 0.9727106355998352, "AIMOVIG": 0.493282862780476, "ALEMTUZUMAB": 0.3598049801297039, "AMBRISENTAN": 1.7413501519425074, "ANORO": 2.513492137373364, "APIXABAN": 3.9667844266015866, "ARAVA": 0.4764508181688268, "ASPARAGINASE": 2.687526536131911, "ATRIPLA": 0.0232627008521577, "AUBAGIO": 0.6541252336894442, "AVAMYS": 11.876380358729463, "AVASTIN": 0.6590195911990511, "BENLYSTA": 2.959161850835874, "BEVACIZUMAB": 0.471848504196897, "BEXSERO": 1.305371921907518, "BIKTARVY": 0.4461480786064077, "BRINTELLIX": 0.283965185177622, "BUDESONIDE": 4.815145659535723, "BUPRENORPHINE": 0.450001002266527, "BYDUREON": 0.8505154765196347, "CELLCEPT": 0.2005800700264895, "CHAMPIX": 0.6443060562670195, "CICLOSPORIN": 0.3209216324844613, "CIMZIA": 0.4510784627496231, "CLOPIDOGREL": 0.1750863213398632, "COMIRNATY": 1.36050191605405, "COSENTYX": 2.54288679212018, "CYMBALTA": 0.2120169843584003, "CYTARABINE": 1.511472157814521, "DARZALEX": 3.3710487144258328, "DEXAMETHASONE": 0.5040522203273252, "DULOXETINE": 1.1525189038359225, "ELIQUIS": 0.4872156115170414, "ENBREL": 0.4916640827317359, "ENTRESTO": 1.0011132611294908, "ENTYVIO": 0.8243196335130403, "ESBRIET": 1.5288352071886595, "EVEROLIMUS": 1.1376953351803554, "EXFORGE": 0.6845499046081154, "EXJADE": 0.3459456850106906, "EYLEA": 0.623345726937804, "FASENRA": 1.4416260987693523, "FASLODEX": 0.6382899339212063, "FLUCELVAX": 5.865614095846057, "FLUTICASONE": 4.646828692250423, "FORXIGA": 0.5392400162488192, "GALAFOLD": 5.519666429598175, "GARDASIL": 0.517774999202115, "HERCEPTIN": 0.956918411638766, "HIZENTRA": 0.8524369139774627, "HUMALOG": 0.1461216283434818, "HUMIRA": 1.5477819282084349, "IBRANCE": 1.6708805134458953, "IBUPROFEN": 0.6555254537198366, "INCRUSE": 2.681956772739372, "INFANRIX": 1.2178002096770486, "INLYTA": 0.6721020746637288, "INSULIN": 2.599670084640165, "IRON": 1.688447913112326, "JANUMET": 0.6995608935177543, "JANUVIA": 0.7921241562176891, "JARDIANCE": 0.2160018734862951, "KAFTRIO": 1.1261274500018403, "KALETRA": 0.304043226559074, "KEPPRA": 0.3011549659128071, "KESIMPTA": 3.2106796698796525, "KEYTRUDA": 0.1673933738539361, "LANTUS": 0.1373511211608574, "LEFLUNOMIDE": 1.446295224517095, "LIXIANA": 0.6538161041642866, "LYRICA": 0.3848023182521295, "MENVEO": 1.5956148093959306, "MEPOLIZUMAB": 5.112885384448852, "METHOTREXATE": 1.0866864074488187, "MICARDIS": 0.8235008763803794, "MMRVAXPRO": 2.561623267502285, "MODERNA": 0.8257750441857669, "NAGLAZYME": 8.644132215498562, "NEULASTA": 0.3878056873455458, "NEXAVAR": 0.1195921595010039, "NIMENRIX": 1.878163654745356, "NUCALA": 7.340765599905777, "OCRELIZUMAB": 1.9203553671774705, "OFEV": 1.219960966945714, "OMALIZUMAB": 3.647360537415581, "OPSUMIT": 1.4661128786304536, "ORKAMBI": 0.9814634281478968, "PANTOPRAZOLE": 0.5360508449048251, "PEGASYS": 0.2126155106616208, "PEGINTRON": 0.210261518206621, "PLAVIX": 0.2532949104708303, "PREVENAR": 5.3202770547123865, "RELVAR": 4.440984642980419, "REVATIO": 1.515499202712625, "RINVOQ": 0.6104095071739983, "RITUXIMAB": 1.3174480673888325, "ROACTEMRA": 0.3918641220573545, "ROTATEQ": 1.4625855363405678, "SAXENDA": 0.348276897314276, "SHINGRIX": 0.4769563426561818, "SIMPONI": 0.7987489240994163, "SOLIRIS": 0.5664046619606968, "SPIKEVAX": 0.9659167406487356, "SPINRAZA": 0.8284962149754979, "SPRYCEL": 0.2853976354281171, "STELARA": 0.7523583146607723, "SUBOXONE": 1.2418146913563757, "SUTENT": 0.3356923875283185, "SYNAGIS": 7.858839977660247, "SYNFLORIX": 6.683469626978567, "TAGRISSO": 0.6383998656507788, "TAMIFLU": 1.1142478344118862, "TASIGNA": 0.3524545212382458, "TOPOTECAN": 1.6799586635558963, "TOZINAMERAN": 3.1708358649199666, "TRACLEER": 0.3386816331233092, "TRELEGY": 2.1180682317428574, "TWINRIX": 0.5589623820851748, "VAXZEVRIA": 1.342385980751597, "VIAGRA": 0.3254159307793822, "VOTRIENT": 0.4639738915230323, "XELJANZ": 2.305155560770383, "XOLAIR": 2.344692654500089, "XTANDI": 0.8164820314089587, "ZOSTAVAX": 0.6006994150408674, "ZYPREXA": 0.0848479403979316, "null": 0.7453025558763057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10561.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10561.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10562.json
new file mode 100644
index 00000000000..345f343827e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10562.json
@@ -0,0 +1 @@
+{"null": 2.588873808515698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10563.json
new file mode 100644
index 00000000000..1b60c274cd4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10563.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.5938786540268517, "ALEMTUZUMAB": 7.192764305775098, "ASPARAGINASE": 102.53648638889446, "BENRALIZUMAB": 92.49649448687278, "BUSULFAN": 16.99197113677949, "CICLOSPORIN": 1.6654922386202509, "CYTARABINE": 49.558251283999525, "ORKAMBI": 27.60171613281335, "SPINRAZA": 215.56437940435765, "SYNAGIS": 180.1941662888103, "TRACLEER": 11.829268524495577, "null": 0.4280640270552889}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10564.json
new file mode 100644
index 00000000000..520f6eff379
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10564.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 31.808943393275914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10565.json
new file mode 100644
index 00000000000..590d9bafbb1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10565.json
@@ -0,0 +1 @@
+{"BIKTARVY": 21.339886093385932, "BUDESONIDE": 5.612586226939975, "CLOPIDOGREL": 3.253162436980803, "COMIRNATY": 0.2131287081647566, "MELATONIN": 36.050176963731566, "NUCALA": 8.89771712146486, "XOLAIR": 9.19097870107115, "null": 1.4713190369955855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10566.json
new file mode 100644
index 00000000000..4abe702e912
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10566.json
@@ -0,0 +1 @@
+{"BUPIVACAINE": 227.08604670742065, "FENTANYL": 31.21746979070176, "null": 2.973936754233856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10567.json
new file mode 100644
index 00000000000..7356d33a96c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10567.json
@@ -0,0 +1 @@
+{"null": 1.0958409605194477}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10568.json
new file mode 100644
index 00000000000..cbd09332702
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10568.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.4776621674654251, "AIMOVIG": 4.93392906608817, "APIDRA": 0.7647285091988559, "ARAVA": 0.1955288652873243, "ATRIPLA": 14.367078261012106, "AUBAGIO": 0.522854977024665, "AVANDIA": 0.4448796634945819, "BENLYSTA": 0.8841711187757587, "BONVIVA": 3.260998281005002, "BUPRENORPHINE": 2.644110365144293, "BYETTA": 0.8266278814479768, "CIMZIA": 0.3524597913991203, "CLOPIDOGREL": 0.32494866411237, "COMIRNATY": 0.0523277818140273, "COSENTYX": 0.4520745036601997, "CYMBALTA": 0.7991111561671431, "DEXAMETHASONE": 1.353002552411886, "ELIQUIS": 1.455365848660469, "ENTRESTO": 0.475743103361252, "ESBRIET": 2.7305056769596114, "EVENITY": 5.490175872880482, "EVISTA": 10.43618475420748, "EXFORGE": 1.891952762462656, "EXJADE": 0.5738332484097995, "FASLODEX": 1.7259222698096046, "FENTANYL": 0.6194625907865718, "FIRDAPSE": 10.17001388322952, "FORSTEO": 5.246461201054666, "HEPSERA": 16.381379774631004, "HUMALOG": 2.152803621970888, "HUMIRA": 0.6197236747734126, "IBRANCE": 1.9554275324491277, "INCRUSE": 6.063877870495214, "IRON": 4.399690000498744, "JARDIANCE": 0.5909645959779461, "KEPPRA": 0.8869493395089617, "KEYTRUDA": 0.2997496861471105, "LANTUS": 1.392111868094884, "LYRICA": 0.9480844675557056, "METHOTREXATE": 0.6027021131027159, "MICARDIS": 1.2088958547200326, "NINLARO": 3.5169239498910576, "NORVIR": 2.2766374056063348, "NUCALA": 0.508347047745371, "OPSUMIT": 0.6404880750301952, "PEGASYS": 0.3881944859574076, "PEGINTERFERON": 0.9463435786127964, "PLAVIX": 0.2875395226441452, "REVATIO": 1.4515337919337574, "SIMPONI": 1.4372045191601197, "SPIKEVAX": 0.0931707055322556, "STELARA": 0.3312381926170585, "STRIBILD": 12.038808566425972, "SUBOXONE": 5.799742982182621, "SUTENT": 0.5752422174472646, "TOZINAMERAN": 0.1413652241815667, "TRACLEER": 0.7772631499668751, "TRELEGY": 3.3966645977653016, "TREMFYA": 1.431823483444121, "TRUVADA": 10.124787128807911, "VAXZEVRIA": 0.02915470252282, "VFEND": 0.788783188038008, "VIAGRA": 1.8187403747344768, "VIMPAT": 1.5485485129082572, "VIREAD": 7.506233451525775, "XELJANZ": 4.5024582124805255, "XOLAIR": 1.4688985217270385, "XTANDI": 2.897442286644785, "ZOSTAVAX": 0.7504249435840596, "ZYPREXA": 0.6317106126649723, "null": 0.8585265460426521}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10569.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10569.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1057.json
index 8a9942bece3..ae0987c2b9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1057.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1057.json
@@ -1 +1 @@
-{"null": 7.408067933199498}
\ No newline at end of file
+{"null": 1.6587268853734356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10570.json
new file mode 100644
index 00000000000..6b64f8773a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10570.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 33.71190430521264, "CYTARABINE": 14.632347746663056, "DOXORUBICIN": 109.25620126299856, "IMBRUVICA": 176.60604268410717, "RITUXIMAB": 50.94132659808098, "VENCLYXTO": 427.98059946162687, "VENETOCLAX": 582.5897667451836, "null": 0.2075540843561511}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10571.json
new file mode 100644
index 00000000000..d127a37fb95
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10571.json
@@ -0,0 +1 @@
+{"null": 2.487321148740122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10572.json
new file mode 100644
index 00000000000..72c99e9d59d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10572.json
@@ -0,0 +1 @@
+{"null": 7.976638727347073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10573.json
new file mode 100644
index 00000000000..374a796ef2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10573.json
@@ -0,0 +1 @@
+{"BUMETANIDE": 556.5390627621568, "IBUPROFEN": 68.13190629996535, "null": 0.3105256303692887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10574.json
new file mode 100644
index 00000000000..6347bf8a506
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10574.json
@@ -0,0 +1 @@
+{"ENTRESTO": 21.581307794944863, "null": 1.6077817761786228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10575.json
new file mode 100644
index 00000000000..9c0c36011b6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10575.json
@@ -0,0 +1 @@
+{"ALENDRONATE": 12944.022537291452, "APIXABAN": 290.1765638991612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10576.json
new file mode 100644
index 00000000000..db7aae691de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10576.json
@@ -0,0 +1 @@
+{"null": 1.358446126336236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10577.json
new file mode 100644
index 00000000000..c6835180ec8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10577.json
@@ -0,0 +1 @@
+{"null": 3.1560025990362823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10578.json
new file mode 100644
index 00000000000..d9c31e9c671
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10578.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2201292785542039, "IBUPROFEN": 33.74201514650552, "OPSUMIT": 15.828299040356326, "SPIKEVAX": 0.5358307679101065, "null": 0.8953638838054971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10579.json
new file mode 100644
index 00000000000..4b65da52058
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10579.json
@@ -0,0 +1 @@
+{"BEDAQUILINE": 28.69246175133772, "COMIRNATY": 0.1736090808235507, "DASATINIB": 115.5225267784365, "ENTRESTO": 9.651148461207525, "MEPOLIZUMAB": 11.43245582346952, "OPSUMIT": 28.881470385082352, "SILDENAFIL": 46.2597280487371, "SPIKEVAX": 0.2542120253630833, "TRACLEER": 19.92864815176336, "VAXZEVRIA": 0.1994122004024794, "null": 0.6680743789312537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1058.json
index 277b1e6475a..8c904b41142 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1058.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1058.json
@@ -1 +1 @@
-{"ABASAGLAR": 29.97973339863641, "ACTOS": 4.793153217274795, "ACTRAPID": 35.44021146286171, "ANAKINRA": 2.1190273500288237, "APIDRA": 35.05051604653073, "BYDUREON": 8.447441990114704, "BYETTA": 6.160157910798752, "CAPECITABINE": 1.1111986087261607, "COAPROVEL": 2.14268050708492, "EMPAGLIFLOZIN": 3.053651763666667, "FIASP": 67.73853125733328, "FORXIGA": 6.830270971858616, "GALVUS": 7.83069628745645, "HUMALOG": 30.054909609116542, "INSULATARD": 10.586122428393352, "INSULIN": 39.69045422631204, "INSUMAN": 44.4145866971573, "JANUMET": 5.73702176649127, "JANUVIA": 3.8786111760741258, "JARDIANCE": 1.1950865188586066, "LANTUS": 33.10225696034378, "LEVEMIR": 49.34411776392753, "LIPROLOG": 41.27105490551752, "LYUMJEV": 29.7734680108193, "MIXTARD": 19.7366608186142, "NOVORAPID": 56.583154744522645, "ONGLYZA": 5.801736209922603, "TOUJEO": 36.943233230655885, "TRESIBA": 25.67302017667002, "TRULICITY": 2.718203392811243, "VICTOZA": 3.3877568447712973}
\ No newline at end of file
+{"ABILIFY": 1.6471367249000757, "ACTRAPID": 12.634981242525924, "ARIPIPRAZOLE": 2.1169998358524684, "BUDESONIDE": 3.017685138202077, "BUPRENORPHINE": 12.83491888556228, "CHAMPIX": 0.8907141073981477, "CLOPIDOGREL": 0.8844372527283492, "COMIRNATY": 0.1301504026586232, "CYMBALTA": 0.5685523807442503, "DARZALEX": 7.798539548111271, "DEXAMETHASONE": 0.879838231653565, "ELIQUIS": 0.213959203788876, "ENTRESTO": 1.080028687818476, "EXFORGE": 4.232353464507827, "FENTANYL": 2.9110379010938736, "GARDASIL": 0.4388521659592936, "HUMALOG": 0.3270199544559086, "IBRANCE": 0.3423000044517527, "INSULIN": 1.2993650296686294, "KEPPRA": 0.4570927883449951, "KEYTRUDA": 0.5418045825923393, "LANTUS": 0.4100418644184175, "LYRICA": 0.9752334555586096, "MEPOLIZUMAB": 3.855459047678411, "NUCALA": 2.0573221726643487, "OLANZAPINE": 2.433319362479616, "OMALIZUMAB": 1.5782250599624243, "PLAVIX": 0.5446377019660436, "PREGABALIN": 2.827547709636631, "RELVAR": 6.064662161264986, "RISPERIDONE": 7.301962654714328, "ROTATEQ": 3.839890286940167, "SPIKEVAX": 0.0470042037349032, "SUBOXONE": 1.1092790143002844, "SUTENT": 0.4896393818729491, "SYNAGIS": 2.152085770439844, "TICAGRELOR": 37.63570374965063, "TOUJEO": 3.1347416653246403, "TOZINAMERAN": 0.2973497710856704, "VAXZEVRIA": 0.0933455047896697, "XELJANZ": 0.3179448168224236, "XOLAIR": 1.461223828318266, "ZYPREXA": 1.0916766214881577, "null": 3.391614018407021}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10580.json
new file mode 100644
index 00000000000..007f8b9d967
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10580.json
@@ -0,0 +1 @@
+{"null": 1.5064132175410418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10581.json
new file mode 100644
index 00000000000..3ac921ac42f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10581.json
@@ -0,0 +1 @@
+{"ADCIRCA": 31.74211611495988, "ADEMPAS": 34.15061787427038, "AMBRISENTAN": 55.299270670161874, "AVANDIA": 1.4328827098640533, "BEDAQUILINE": 7.348301898010085, "BOSENTAN": 98.78318907556049, "BUSULFAN": 4.982621938883884, "COMIRNATY": 0.0879866789053085, "DAPAGLIFLOZIN": 21.902004383062728, "ELIQUIS": 0.5270410598036429, "ENTRESTO": 1.063683575487374, "IBUPROFEN": 2.7268677848778764, "MACITENTAN": 45.76092040542371, "OFEV": 4.051303740074024, "OPSUMIT": 87.07431777768922, "REVATIO": 30.143693775905938, "SILDENAFIL": 34.66589698568978, "SPIKEVAX": 0.0588537581372185, "SPRYCEL": 3.661962088952216, "TRACLEER": 136.42799760721908, "VAXZEVRIA": 0.0475723799311127, "VIAGRA": 1.4283640668385136, "XARELTO": 3.661995248119708, "null": 0.9285213560712082}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10582.json
new file mode 100644
index 00000000000..3d705afcf74
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10582.json
@@ -0,0 +1 @@
+{"ALENDRONATE": 1641.0702669251425, "APIXABAN": 29.40522693554893, "OPSUMIT": 7.782077008442995, "null": 2.248502101262333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10583.json
new file mode 100644
index 00000000000..a458f74d17f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10583.json
@@ -0,0 +1 @@
+{"OPSUMIT": 29.215634809565817, "null": 0.6943412800430605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10584.json
new file mode 100644
index 00000000000..198d2e4756b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10584.json
@@ -0,0 +1 @@
+{"TRACLEER": 242.0200617494706, "null": 0.3448040397031988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10585.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10585.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10586.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10586.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10587.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10587.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10588.json
new file mode 100644
index 00000000000..b43cec0c285
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10588.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.6965766329890207, "ABILIFY": 0.7108477652622515, "ADALIMUMAB": 2.033708452481954, "ADVATE": 4.55197166552746, "AFINITOR": 0.2646644851950075, "AIMOVIG": 1.890134755233125, "APIDRA": 2.489814026548944, "ARAVA": 0.4877851163490366, "ATRIPLA": 0.0847254574913665, "AUBAGIO": 1.251031090965414, "AVANDIA": 0.2176994394646795, "BENLYSTA": 0.8503955435628755, "BIKTARVY": 0.913126615209286, "BRILIQUE": 0.6115626225728774, "BRINTELLIX": 0.7953085230402627, "BRIVIACT": 1.901497748227088, "BUPRENORPHINE": 4.471958111123314, "BYDUREON": 1.327241348741394, "BYETTA": 2.113078741334117, "CELECOXIB": 7.658578886873633, "CHAMPIX": 6.422506228763827, "CIMZIA": 0.8862035932689806, "COMIRNATY": 0.0638201606818512, "COMTAN": 4.141294074063699, "COSENTYX": 1.1681160233942822, "CYMBALTA": 1.7436476207153904, "ELIQUIS": 1.5322784315695752, "ENBREL": 0.3209920828249405, "EPIVIR": 3.20995362622218, "ESBRIET": 1.3834097741809694, "EVENITY": 1.5148150669463556, "EVISTA": 2.624673542708273, "EXFORGE": 1.4017390903513127, "EXJADE": 1.1308746500518274, "FAMPYRA": 1.0155759838105118, "FASENRA": 0.6308703815009146, "FENTANYL": 2.137333290543374, "FORSTEO": 1.5166657732330706, "FORXIGA": 0.7287954654811023, "GARDASIL": 0.4954843010729117, "HARVONI": 1.3635490627306122, "HEMLIBRA": 3.418749076493913, "HIZENTRA": 0.7332402119129424, "HUMALOG": 7.132594840233058, "HUMIRA": 1.588642108401236, "IBRANCE": 0.6939150964786897, "IBUPROFEN": 0.3578365006228431, "INLYTA": 1.15105447458213, "INSULIN": 2.293436635232934, "JANUVIA": 1.915354290912917, "JARDIANCE": 1.227649500249844, "KAFTRIO": 1.022669465594274, "KEPPRA": 2.13191146500419, "LANTUS": 4.270213203043893, "LATUDA": 2.295264592706149, "LEVEMIR": 3.053204940129246, "LEVETIRACETAM": 0.7950255295739539, "LYRICA": 6.228408289677032, "MEPOLIZUMAB": 0.3842042896037959, "METHOTREXATE": 0.4104145642674734, "MICARDIS": 2.281640535556205, "NOVORAPID": 1.232144771664967, "NUCALA": 0.2783268362373882, "OLANZAPINE": 0.5783206676959955, "OMALIZUMAB": 1.722668862590888, "OPSUMIT": 1.1655002123955325, "OZEMPIC": 4.886294171118387, "PEGASYS": 1.7561001104376732, "PEGINTERFERON": 1.092949216246618, "PEGINTRON": 1.6195764466039737, "PLAVIX": 0.6635455770909858, "PREGABALIN": 1.035399340464655, "REMICADE": 1.57078368289282, "REVATIO": 1.336359500239128, "RUCONEST": 3.083005395505062, "SAXENDA": 1.025669078556888, "SIFROL": 4.237886059468402, "SIMPONI": 1.5719963241919228, "SOLIRIS": 0.7587121989243225, "SOVALDI": 1.4807323489323363, "SPIKEVAX": 0.0654249302058763, "SPINRAZA": 2.320446465359991, "SPRYCEL": 0.7239082441474132, "STELARA": 1.4370476142641102, "STRIBILD": 0.3030698681828086, "SUBOXONE": 14.88204689025024, "SUTENT": 0.3330743105442325, "TAMIFLU": 0.6830982317595209, "TASIGNA": 0.6614508040085019, "TOVIAZ": 2.2744803416205794, "TOZINAMERAN": 0.1453289584767169, "TRACLEER": 1.0817998684001429, "TRELEGY": 1.732139099746069, "TREMFYA": 1.8725696672801424, "TRESIBA": 2.666084860409773, "TRULICITY": 1.1258345726507746, "TRUVADA": 0.129264767121611, "VAXZEVRIA": 0.0170714869447371, "VFEND": 0.4318687105318507, "VIAGRA": 9.19918756923096, "VIMPAT": 0.9600194197550508, "VOTRIENT": 0.4020586633155439, "XELJANZ": 2.4554354666601514, "XOLAIR": 1.7085517469880669, "XTANDI": 1.0212655735886045, "XYREM": 4.025683305634043, "ZOSTAVAX": 1.0271891352069522, "ZYPREXA": 1.7402885232875145, "null": 1.72162984717023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10589.json
new file mode 100644
index 00000000000..810ba4fdfba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10589.json
@@ -0,0 +1 @@
+{"null": 0.5500856115978128}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1059.json
index c6bf5f5aec1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1059.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1059.json
@@ -1 +1 @@
-{"ABASAGLAR": 36.43872731950109, "ABILIFY": 2.7669754743843997, "ACTOS": 6.531088396334462, "ACTRAPHANE": 26.998733641471016, "ACTRAPID": 18.67705150122187, "AFINITOR": 1.7710242732599175, "ALPELISIB": 5.336804459230629, "ANTIBIOTICS": 1.0075447137526314, "APIDRA": 22.68102677647207, "APIXABAN": 2.4294750016068587, "BAQSIMI": 7.972321510755766, "BYDUREON": 8.725857667282526, "BYETTA": 6.775495733939718, "CORTICOSTEROIDS": 3.979184796112179, "DESCOVY": 1.0720855878097144, "DRUG": 4.5298597944080345, "DULAGLUTIDE": 22.68334547056177, "EMPAGLIFLOZIN": 1.9699847987334365, "EUCREAS": 3.7479470361611016, "EXFORGE": 1.3609352832103832, "EXUBERA": 19.75753765638221, "FIASP": 51.15097948118381, "FORXIGA": 3.9498058250295713, "GALVUS": 12.042865731722754, "GLIBENCLAMIDE": 3.96832630937974, "GLUCAGON": 6.739463185007669, "HUMALOG": 43.88325485232816, "ICANDRA": 4.906519065630417, "INSULATARD": 13.3206893187496, "INSULIN": 17.333196207889802, "INSUMAN": 24.24844516194957, "INTELENCE": 1.3164658641984277, "INVOKANA": 1.1005516062599234, "ISCOVER": 1.7285100188348534, "ISOPHANE": 8.15665935778768, "JANUMET": 5.608937464255798, "JANUVIA": 4.498967441447852, "JARDIANCE": 3.4299067612660146, "KARVEA": 1.2938942525074155, "LANTUS": 26.23893052299988, "LATUDA": 1.163846512638808, "LEVEMIR": 32.632497950668935, "LIPROLOG": 87.89101787049886, "LIRAGLUTIDE": 1.4060352936615432, "LYUMJEV": 29.78010194026098, "MEMANTINE": 1.2346400960028523, "METFORMIN": 4.824011318469732, "MIXTARD": 21.191317283004476, "MOUNJARO": 7.70676283649294, "NALOXONE": 1.7470267696500472, "NOVOMIX": 10.042285367449557, "NOVONORM": 2.9686170471008397, "NOVORAPID": 62.05921934681912, "ONGLYZA": 5.166667893991179, "OZEMPIC": 5.928885522999684, "PASIREOTIDE": 7.9578876685045135, "PIOGLITAZONE": 1.32941508410994, "PIQRAY": 12.713191127032475, "PRANDIN": 8.331648465286401, "PROTAPHANE": 38.649599433919406, "RASILEZ": 1.4644338735677702, "REPAGLINIDE": 2.940196085464504, "RYBELSUS": 5.988169858558681, "SEMAGLUTIDE": 1.6294837581614816, "SEMGLEE": 10.244760568773994, "SIGNIFOR": 6.740362856729726, "SITAGLIPTIN": 2.143764055540013, "TASIGNA": 1.3902838530146986, "TORISEL": 1.522698457052083, "TOUJEO": 31.48533019181776, "TRESIBA": 24.89259312866018, "TRULICITY": 10.073416218937318, "VICTOZA": 8.438156748718939, "VILDAGLIPTIN": 2.83613018404912, "ZYPREXA": 2.584120456938054}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10590.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10590.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10591.json
new file mode 100644
index 00000000000..1c58ab213b5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10591.json
@@ -0,0 +1 @@
+{"null": 1.357340192540443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10592.json
new file mode 100644
index 00000000000..12e9e4b9c88
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10592.json
@@ -0,0 +1 @@
+{"HUMIRA": 247.9809353710986, "XELJANZ": 15.5947126452508, "null": 0.2227338004811896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10593.json
new file mode 100644
index 00000000000..9e5e32f4323
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10593.json
@@ -0,0 +1 @@
+{"ARAVA": 0.5388406685467267, "COMIRNATY": 0.8619950171593657, "COSENTYX": 1.5230751708390071, "MIRABEGRON": 69.51356078794029, "MIRVASO": 711.5949721018367, "RINVOQ": 28.782105964682536, "SPIKEVAX": 0.5775311442066603, "TOZINAMERAN": 0.7767573821837974, "VAXZEVRIA": 0.4088293054192918, "XELJANZ": 3.6028672039732297, "ZOSTAVAX": 8.802005070006937, "null": 0.8813878072029033}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10594.json
new file mode 100644
index 00000000000..343c1f0118f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10594.json
@@ -0,0 +1 @@
+{"null": 4.063471053120371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10595.json
new file mode 100644
index 00000000000..8d0c929cf4a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10595.json
@@ -0,0 +1 @@
+{"null": 0.7783440919244126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10596.json
new file mode 100644
index 00000000000..525c6a45af6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10596.json
@@ -0,0 +1 @@
+{"BYETTA": 13.606263001410984, "JANUMET": 12.670582614032336, "LANTUS": 6.821847291870877, "METHOTREXATE": 88.96075871633568, "XELJANZ": 7.314887554218812, "ZOSTAVAX": 5.4619059323245, "null": 0.7644856595359683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10597.json
new file mode 100644
index 00000000000..69bf21232fe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10597.json
@@ -0,0 +1 @@
+{"ARAVA": 0.3412023589162953, "ATRIPLA": 0.4718970012156706, "BYETTA": 2.704555257417912, "CIMZIA": 0.6735130919698742, "COMIRNATY": 0.5510826808616831, "COSENTYX": 0.6339620200708753, "CYMBALTA": 7.065561557502653, "DEXAMETHASONE": 1.0997591415573515, "DULOXETINE": 3.549543906534609, "ELIQUIS": 0.7224185587877373, "ENBREL": 2.217804877003217, "FLUTICASONE": 8.140880015081061, "HUMALOG": 2.913458050938301, "HUMIRA": 2.513231398038109, "IBRANCE": 0.7806752159427433, "LANTUS": 2.372395043643021, "LEVOFLOXACIN": 6.5604790059819, "MIRABEGRON": 25.548840965612587, "MODERNA": 0.9669107470060448, "OPSUMIT": 1.0050840612315937, "SIMPONI": 0.6270858239604074, "SPIKEVAX": 0.379904145165043, "SUBOXONE": 1.2711064533887, "TOZINAMERAN": 0.7194135105571755, "TRUVADA": 0.4931997859862849, "VAXZEVRIA": 0.4702863571451666, "VIAGRA": 3.1146242617501745, "XELJANZ": 3.5599127595359463, "XOLAIR": 0.8999286461313971, "ZOSTAVAX": 7.6423455653227235, "null": 1.7861613687057487}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10598.json
new file mode 100644
index 00000000000..4f6a31c7f41
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10598.json
@@ -0,0 +1 @@
+{"ROTARIX": 278.5709048829182, "ROTATEQ": 1864.961970002797, "SYNAGIS": 18.476268971275363, "null": 0.3648347794602475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10599.json
new file mode 100644
index 00000000000..a3bfc9f841c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10599.json
@@ -0,0 +1 @@
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/106.json
index 9612b0e420b..44c0b6ffa35 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/106.json
@@ -1 +1 @@
-{"null": 4.355173022300543}
\ No newline at end of file
+{"null": 1.4091669509216829}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1060.json
index 9bab6665862..ebe9139cfe1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1060.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1060.json
@@ -1 +1 @@
-{"GARDASIL": 46.021967412803335, "JARDIANCE": 34.80169784181882, "SPIKEVAX": 8.519953765621457}
\ No newline at end of file
+{"ABILIFY": 1.922400774603938, "ACLIDINIUM": 6.722209175374538, "APROVEL": 8.440067063008858, "ARANESP": 7.156391619343679, "AUBAGIO": 0.8753432898614296, "BRIDION": 5.075066438870195, "BUDESONIDE": 16.005811164473187, "BUPRENORPHINE": 7.273092373186859, "CLOPIDOGREL": 0.6027910087931014, "COMIRNATY": 0.0995054719709917, "COMTAN": 5.616510836806592, "CYMBALTA": 0.8562227921097465, "ELIQUIS": 1.2510007638377667, "EMEND": 8.572635537133758, "FENTANYL": 1.9431553156409345, "FIRDAPSE": 4.75929026938899, "HUMALOG": 0.6537599318406323, "IBUPROFEN": 4.54225494009999, "KEPPRA": 3.2704402130765966, "KEYTRUDA": 0.5476142213181854, "LANTUS": 0.3023884334347319, "LEVETIRACETAM": 2.954466996728858, "LYRICA": 1.8566674868420616, "MIDAZOLAM": 12.897451021167164, "NEXAVAR": 0.5908006653622819, "NUCALA": 4.980807844715817, "OFEV": 1.6619062180819673, "OLANZAPINE": 4.26976644211369, "PLAVIX": 1.021982932642329, "PREGABALIN": 4.661003713717296, "ROTATEQ": 1.9923850743015723, "SPIKEVAX": 0.152291878578061, "SPINRAZA": 33.10227313430038, "STALEVO": 4.96983879617291, "SUBOXONE": 1.1142782923618952, "SUTENT": 0.2789955539820106, "SYNAGIS": 11.833684310483688, "TOZINAMERAN": 0.1207390289244844, "TRACLEER": 1.4418529766708394, "TRELEGY": 2.74423057262852, "VAXZEVRIA": 0.0408495498969171, "XTANDI": 1.8646386222761024, "ZYPREXA": 3.030996202754517, "null": 1.9350978026472192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10600.json
new file mode 100644
index 00000000000..b934c698616
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10600.json
@@ -0,0 +1 @@
+{"ROTATEQ": 10751.495924523562}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10601.json
new file mode 100644
index 00000000000..4abdd7ea39c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10601.json
@@ -0,0 +1 @@
+{"PAZOPANIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10602.json
new file mode 100644
index 00000000000..7229e365bbd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10602.json
@@ -0,0 +1 @@
+{"ABILIFY": 10.022344975172466, "AIMOVIG": 57.2787135260053, "OMALIZUMAB": 67.94068728294309, "STELARA": 8.560914880083164, "XOLAIR": 7.043352307243448, "null": 0.4126565803219287}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10603.json
new file mode 100644
index 00000000000..5920bf49c70
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10603.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2548340986844526, "MMRVAXPRO": 40.41853472716425, "null": 3.3936014844801683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10604.json
new file mode 100644
index 00000000000..d866410c652
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10604.json
@@ -0,0 +1 @@
+{"MMRVAXPRO": 90.74842407454018, "null": 5.971338022270156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10605.json
new file mode 100644
index 00000000000..056e5b4282b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10605.json
@@ -0,0 +1 @@
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10606.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10606.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10607.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10607.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10608.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10608.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10609.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10609.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1061.json
index 0e3a0bda1f3..2652ad31f79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1061.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1061.json
@@ -1 +1 @@
-{"null": 4.422873492092894}
\ No newline at end of file
+{"null": 0.9728078020631838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10610.json
new file mode 100644
index 00000000000..2bcf18b3cba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10610.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8254018582766119, "SPIKEVAX": 0.4271987353872447, "TOZINAMERAN": 1.1708256392178025, "VAXZEVRIA": 0.2952733471131107, "null": 0.864257340369569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10611.json
new file mode 100644
index 00000000000..4f10e00d914
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10611.json
@@ -0,0 +1 @@
+{"null": 1.722962529067409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10612.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10612.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10613.json
new file mode 100644
index 00000000000..4cc35e8d562
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10613.json
@@ -0,0 +1 @@
+{"ENBREL": 70.22840626655307, "null": 0.6127986984377405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10614.json
new file mode 100644
index 00000000000..8545cb935e9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10614.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.9169185271388414, "VAXZEVRIA": 4.498789708728403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10615.json
new file mode 100644
index 00000000000..b44b7815bf1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10615.json
@@ -0,0 +1 @@
+{"COMIRNATY": 10.118490602244329, "SPIKEVAX": 2.115360732458852, "TOZINAMERAN": 0.8306859126033775, "VAXZEVRIA": 1.961794653173162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10616.json
new file mode 100644
index 00000000000..721f8f2ebc9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10616.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.56437565078739, "PRIVIGEN": 33.16774962029323, "TOZINAMERAN": 1.5638418812408146, "VAXZEVRIA": 1.2621451916047377, "null": 0.1177994061380625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10617.json
new file mode 100644
index 00000000000..4acbd9dc4bf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10617.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.3597610065755137, "ENTRESTO": 27.96750828522805, "SPIKEVAX": 2.680299963082656, "VAXZEVRIA": 3.09716803473525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10618.json
new file mode 100644
index 00000000000..39528774cff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10618.json
@@ -0,0 +1 @@
+{"CIMZIA": 5.4874697067785005, "COMIRNATY": 3.1721936968124043, "FASENRA": 13.31751587192761, "KEPPRA": 2.533301067172416, "SPIKEVAX": 1.45363518989087, "TAGRISSO": 12.007149456124772, "VAXZEVRIA": 2.760708495761472, "null": 0.118592064220633}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10619.json
new file mode 100644
index 00000000000..c507f2fd814
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10619.json
@@ -0,0 +1 @@
+{"ACTRAPID": 6.7637408373775605, "AIMOVIG": 0.401135871979058, "ARIPIPRAZOLE": 5.0544471936301445, "AUBAGIO": 2.7378812138530573, "BENLYSTA": 1.123235290088684, "CIMZIA": 1.4053022959282904, "COMIRNATY": 4.4457074317200735, "COSENTYX": 0.7913568468631513, "ENTYVIO": 0.6958214868228767, "FASENRA": 1.6378238619775412, "HIZENTRA": 1.083399189058684, "HUMIRA": 1.3420322501500643, "IBRANCE": 0.3606112136779213, "ICLUSIG": 2.3584602267752177, "JANSSEN": 31.505736418313735, "JARDIANCE": 0.290466282608786, "JCOVDEN": 24.785248983100423, "KAFTRIO": 3.045523213154118, "KESIMPTA": 5.556937183258048, "KEYTRUDA": 0.1802187989420164, "LEMTRADA": 1.7980279958175902, "METFORMIN": 3.699339718112823, "NUCALA": 1.1561604655398503, "OMALIZUMAB": 0.9163899024730996, "PANTOPRAZOLE": 1.1907558536710616, "PLEGRIDY": 2.343851627991173, "RINVOQ": 1.253512350928312, "RITUXIMAB": 1.6627636341156264, "ROACTEMRA": 1.226144888751474, "SEMAGLUTIDE": 12.460136442818133, "SIMPONI": 0.4145798358709818, "SOLIRIS": 4.834011252177906, "SPIKEVAX": 2.9114461030813183, "SPINRAZA": 4.789618612811015, "STELARA": 1.1039566902411602, "SYNAGIS": 1.6186155744305106, "TELMISARTAN": 3.7698750474433584, "TOZINAMERAN": 2.155046444553194, "TRELEGY": 0.6354734196065625, "TREMFYA": 2.473437590364278, "VAXZEVRIA": 1.8507134354850563, "VEKLURY": 15.945922007038895, "XELJANZ": 0.4847905560369598, "XOLAIR": 0.4237221184310132, "null": 0.0695568442432439}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1062.json
index 71286d13b97..a6b3602eb98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1062.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1062.json
@@ -1 +1 @@
-{"ASPARAGINASE": 111.96591464873758, "null": 2.1110273354908933}
\ No newline at end of file
+{"KALETRA": 1041.6651607132662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10620.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10620.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10621.json
new file mode 100644
index 00000000000..8aab128cdc1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10621.json
@@ -0,0 +1 @@
+{"null": 1.306346535786408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10622.json
new file mode 100644
index 00000000000..f9d16b23dc2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10622.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 129.10439108054433, "BELIMUMAB": 2302.5150139179664, "BENLYSTA": 53.664008332320535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10623.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10623.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10624.json
new file mode 100644
index 00000000000..9e47745e700
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10624.json
@@ -0,0 +1 @@
+{"null": 1.0177402932149529}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10625.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10625.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10626.json
new file mode 100644
index 00000000000..7321c2a977e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10626.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.328400806006061, "COSENTYX": 5.819001722519967, "FORSTEO": 4.455969636610332, "IBUPROFEN": 9.528411971130303, "SPIKEVAX": 0.5036163695736698, "SUTENT": 1.9597209236371755, "TOZINAMERAN": 0.7075799925543366, "VAXZEVRIA": 1.283674701511479, "null": 0.382994124453916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10627.json
new file mode 100644
index 00000000000..572cd7aa77c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10627.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.522581185076515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10628.json
new file mode 100644
index 00000000000..5e8f63cba79
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10628.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 6.44454737761109, "ANAKINRA": 41.32133760869912, "CIMZIA": 7.846777653004459, "COMIRNATY": 0.2059904287158482, "COSENTYX": 19.02256774626154, "ENBREL": 12.524814151181609, "ENTYVIO": 7.674486344186157, "GARDASIL": 4.098291570171042, "HUMIRA": 14.292555523912265, "NEVANAC": 122.89683715850722, "SIMPONI": 4.209646608385349, "STELARA": 7.645815520593347, "TOZINAMERAN": 0.4324445472553994, "null": 0.5834700146839801}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10629.json
new file mode 100644
index 00000000000..54ef0e86e5e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10629.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3285238052291749, "PEGASYS": 2.2615832925699286, "SPIKEVAX": 0.4036151436147771, "VAXZEVRIA": 0.2789726991681305, "null": 1.576927255496296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1063.json
index 09a1db8958a..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1063.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1063.json
@@ -1 +1 @@
-{"SOMAVERT": 1567.6136640463608, "null": 4.254257869355732}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10630.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10630.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10631.json
new file mode 100644
index 00000000000..f24a4b3d12c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10631.json
@@ -0,0 +1 @@
+{"null": 1.4853375145356105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10632.json
new file mode 100644
index 00000000000..0e3f2a5bc2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10632.json
@@ -0,0 +1 @@
+{"null": 1.0567857957019913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10633.json
new file mode 100644
index 00000000000..b17078bb2c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10633.json
@@ -0,0 +1 @@
+{"RELVAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10634.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10634.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10635.json
new file mode 100644
index 00000000000..032d51bbd39
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10635.json
@@ -0,0 +1 @@
+{"null": 1.141091914569382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10636.json
new file mode 100644
index 00000000000..ad74792f2a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10636.json
@@ -0,0 +1 @@
+{"NUCALA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10637.json
new file mode 100644
index 00000000000..5a6d7d0cb8d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10637.json
@@ -0,0 +1 @@
+{"null": 0.96931478177762}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10638.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10638.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10639.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10639.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1064.json
index 9deef985af7..10ff9cbbebf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1064.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1064.json
@@ -1 +1 @@
-{"null": 1.5239202029864345}
\ No newline at end of file
+{"null": 0.9240065413979868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10640.json
new file mode 100644
index 00000000000..50ea8710e55
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10640.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2753994008672016, "null": 1.4983953535340335}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10641.json
new file mode 100644
index 00000000000..615946ac967
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10641.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.700211948468451, "MMRVAXPRO": 4.84422517230094, "SPIKEVAX": 0.2114899639755673, "TOZINAMERAN": 0.7208054516659299, "VAXZEVRIA": 0.200035178158617, "null": 3.791660885300016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10642.json
new file mode 100644
index 00000000000..47ea24b9fba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10642.json
@@ -0,0 +1 @@
+{"null": 5.035644672440388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10643.json
new file mode 100644
index 00000000000..5b6961312fa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10643.json
@@ -0,0 +1 @@
+{"null": 0.4323058731990355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10644.json
new file mode 100644
index 00000000000..f8f126e3da0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10644.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.2084466775019125, "MMRVAXPRO": 12.110602093909923, "SPIKEVAX": 0.582228524727758, "VAXZEVRIA": 0.662204241867469, "null": 1.5893160098477217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10645.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10645.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10646.json
new file mode 100644
index 00000000000..666fc3b3ace
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10646.json
@@ -0,0 +1 @@
+{"ABILIFY": 4.658463036717731, "ARIPIPRAZOLE": 12.629509659212458, "BRINTELLIX": 4.417301114937845, "BRIVARACETAM": 9.202114483795578, "CHAMPIX": 0.5981617973041699, "CLOPIDOGREL": 0.4565137716920351, "COMIRNATY": 0.3211141230248605, "CYMBALTA": 0.3659006599589137, "FORSTEO": 0.6055292940782063, "FYCOMPA": 4.643966189416276, "GARDASIL": 0.3641894629635125, "INFANRIX": 5.099259990471248, "INSULIN": 0.8509837760752694, "INVEGA": 18.874056521886285, "KEPPRA": 1.9268404018334149, "LATUDA": 6.848068361054468, "LEVETIRACETAM": 1.8034511917947489, "MIDAZOLAM": 2.9650945843901644, "MMRVAXPRO": 1.8842080260506493, "NIMENRIX": 1.4285167742907514, "OLANZAPINE": 11.728130986716232, "PEGASYS": 0.2169542659502336, "REAGILA": 21.934175384363066, "RISPERIDONE": 30.94256950895232, "SPIKEVAX": 0.1959975306154947, "SPINRAZA": 5.262469862050283, "STALEVO": 5.169761978430663, "SUTENT": 0.6528938045631749, "SYCREST": 9.413352006965628, "TOZINAMERAN": 0.54721724880896, "VAXZEVRIA": 0.2958204231317158, "XTANDI": 0.5489874225498881, "ZYPADHERA": 4.116023395429085, "ZYPREXA": 4.975942141737405, "null": 2.833428857339673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10647.json
new file mode 100644
index 00000000000..d13a21c11da
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10647.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5675093582340726, "KEYTRUDA": 4.113838819314536, "SPIKEVAX": 0.1797840641916287, "SUTENT": 1.7343861994109293, "TOZINAMERAN": 0.4927349921684071, "VAXZEVRIA": 0.2106578479657182, "null": 1.7593724445947545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10648.json
new file mode 100644
index 00000000000..80a6d36936d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10648.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 6.83880966473232, "PEGASYS": 4.93995077456119, "ROTATEQ": 21.529745053860704, "null": 0.6758784696878986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10649.json
new file mode 100644
index 00000000000..6f847dacf5d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10649.json
@@ -0,0 +1 @@
+{"null": 0.5059414636737627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1065.json
index 18283d2061a..900fcf158f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1065.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1065.json
@@ -1 +1 @@
-{"ARAVA": 2.179550263868893, "CYTARABINE": 22.53023608901824}
\ No newline at end of file
+{"ELIQUIS": 7.611101663458864, "OPSUMIT": 24.125080507302645, "SPRYCEL": 197.07918646215867, "null": 0.5641512537219403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10650.json
new file mode 100644
index 00000000000..dbb2f079020
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10650.json
@@ -0,0 +1 @@
+{"null": 0.4076611556508092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10651.json
new file mode 100644
index 00000000000..69bd2d51233
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10651.json
@@ -0,0 +1 @@
+{"CYMBALTA": 56.49827087661525, "null": 0.4905475430431351}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10652.json
new file mode 100644
index 00000000000..23403465503
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10652.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 142.22034834559776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10653.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10653.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10654.json
new file mode 100644
index 00000000000..3aba5e07f84
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10654.json
@@ -0,0 +1 @@
+{"HUMIRA": 248.71273485385325, "null": 0.7375443275018408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10655.json
new file mode 100644
index 00000000000..090703f209b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10655.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 92.18287781947332, "ALEMTUZUMAB": 3.669329837836999, "ANORO": 5.200121920024449, "ARAVA": 1.1960824597794908, "AUBAGIO": 1.8950174032289435, "AVAMYS": 8.407703734351733, "CELLCEPT": 1.3026608424658328, "CIMZIA": 2.447182062679177, "COMIRNATY": 0.5653270748514946, "COSENTYX": 1.6149823618667956, "COTELLIC": 8.190375012864958, "DABRAFENIB": 11.07554627931574, "ENBREL": 0.8186081987755892, "HUMALOG": 1.0274045219572117, "INCIVO": 4.3545107438653625, "INTRONA": 10.236303744746046, "IPILIMUMAB": 10.22796560870914, "KEYTRUDA": 4.183221851282167, "LANTUS": 1.0514169565624247, "MEKINIST": 6.375361993792552, "MEPOLIZUMAB": 3.1931654025227574, "METHOTREXATE": 2.519337770211924, "OPDIVO": 3.400919556746724, "PEGASYS": 14.46405046873486, "PEGINTERFERON": 38.58698353506783, "PEGINTRON": 14.531881927398729, "PEMBROLIZUMAB": 8.470409785933315, "REBETOL": 16.87702577164137, "RIBAVIRIN": 35.234136354622734, "ROACTEMRA": 1.730128689459048, "SIMPONI": 5.992100404854211, "SPIKEVAX": 0.1979867356362401, "STELARA": 3.309966311517723, "TOZINAMERAN": 0.5594142983529053, "TRACLEER": 2.1001413990118114, "VAXZEVRIA": 0.2104036977240116, "XELJANZ": 0.574514810056518, "XOLAIR": 1.6111952133595844, "null": 0.3386148466142571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10656.json
new file mode 100644
index 00000000000..0f2e2772c93
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10656.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 4.936854405935654, "SUTENT": 1.8975761612953617, "VOTRIENT": 77.62989729937053, "YONDELIS": 123.17448561593534, "null": 0.8010507288622862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10657.json
new file mode 100644
index 00000000000..5454e1795d4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10657.json
@@ -0,0 +1 @@
+{"VOTRIENT": 281.6086071350395, "null": 0.3232315137694949}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10658.json
new file mode 100644
index 00000000000..07c29aa7b02
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10658.json
@@ -0,0 +1 @@
+{"ESMYA": 887.0831012578955, "null": 1.0177402932149529}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10659.json
new file mode 100644
index 00000000000..5af3a3340a7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10659.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 30.446492362089035, "null": 0.3104756197821408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1066.json
index 4d2559c6e89..0d0673314cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1066.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1066.json
@@ -1 +1 @@
-{"ANAKINRA": 66.24806939675368, "null": 1.0628633230341202}
\ No newline at end of file
+{"AVAMYS": 667.0337519371697, "null": 0.8482190611827173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10660.json
new file mode 100644
index 00000000000..05ea727a3d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10660.json
@@ -0,0 +1 @@
+{"ALDARA": 66.05235409489354, "BENLYSTA": 1.4729535381691343, "BUPIVACAINE": 3.517931451039673, "CICLOSPORIN": 1.1545691124489086, "CIMZIA": 0.4565370048685827, "COMIRNATY": 0.1257318482587184, "COSENTYX": 3.093719830148212, "CYMBALTA": 0.2885433983212531, "DEXAMETHASONE": 0.8658164164116238, "ELIQUIS": 0.5893878142357557, "GARDASIL": 0.4318593262009647, "HUMIRA": 1.019980540987936, "HYDROCORTISONE": 4.115729441891854, "IBRANCE": 0.7027786722596754, "IMIQUIMOD": 108.97495332841127, "JARDIANCE": 0.5910637000856179, "KEYTRUDA": 1.032977699974981, "METHOTREXATE": 2.767576732037868, "NEXAVAR": 0.8960503372624978, "OPTIMARK": 3.6511365626289, "PEGASYS": 1.036182655729874, "PEGINTRON": 1.0610280796351714, "RENVELA": 284.7009139956396, "RINVOQ": 1.983448455026968, "SHINGRIX": 5.891218744659309, "SPIKEVAX": 0.1007898922295258, "STIVARGA": 1.5328329947061514, "SUTENT": 1.5040651190841563, "TOZINAMERAN": 0.5169564474148288, "VAXZEVRIA": 0.0947720019965554, "XELJANZ": 0.7077737564368876, "ZOSTAVAX": 3.55087335188325, "ZYCLARA": 135.764142320459, "null": 3.1469902797164764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10661.json
new file mode 100644
index 00000000000..c6490dabd28
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10661.json
@@ -0,0 +1 @@
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10662.json
new file mode 100644
index 00000000000..f87adab6652
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10662.json
@@ -0,0 +1 @@
+{"null": 0.459864800196755}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10663.json
new file mode 100644
index 00000000000..94096e97d71
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10663.json
@@ -0,0 +1 @@
+{"ENTRESTO": 363.8191432832047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10664.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10664.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10665.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10665.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10666.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10666.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10667.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10667.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10668.json
new file mode 100644
index 00000000000..c027895e152
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10668.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 13.059603711369263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10669.json
new file mode 100644
index 00000000000..ba54b90d15d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10669.json
@@ -0,0 +1 @@
+{"null": 6.503597527171313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1067.json
index 0cf207b395c..63858b41971 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1067.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1067.json
@@ -1 +1 @@
-{"XOLAIR": 110.40345288820612}
\ No newline at end of file
+{"MEPOLIZUMAB": 184.1422742360961, "null": 1.9917857350684665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10670.json
new file mode 100644
index 00000000000..25a76e6d701
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10670.json
@@ -0,0 +1 @@
+{"ATRIPLA": 23.309426260050543, "null": 0.451230337311873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10671.json
new file mode 100644
index 00000000000..6a103fea5df
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10671.json
@@ -0,0 +1 @@
+{"ALDARA": 8.408695199011598, "APIDRA": 1.4816225935658989, "ARAVA": 1.2456097632252146, "AVANDIA": 1.2839928576042907, "BENLYSTA": 1.3682238777134252, "BUPRENORPHINE": 1.143803503870178, "BYDUREON": 1.0751692895946356, "CHAMPIX": 0.605717173642012, "CICLOSPORIN": 0.5898838066468767, "CIMZIA": 0.7068125243246572, "COMIRNATY": 0.2866215388716357, "CONTRAST": 85.08085862769995, "COSENTYX": 2.386655610132157, "CYMBALTA": 1.1339753240714938, "DEXAMETHASONE": 1.5000066735964628, "ENTYVIO": 1.9544633771087343, "ERTAPENEM": 47.17817987609707, "GARDASIL": 0.9567028496607506, "HUMALOG": 2.944440668168669, "HUMIRA": 2.278185803948503, "IBRANCE": 0.5983574852176342, "JARDIANCE": 0.4848098870414934, "KEPPRA": 0.8043379955074922, "LANTUS": 0.8704486894584001, "LYRICA": 1.920266583691907, "OPTIMARK": 103.21371493084332, "PEGASYS": 0.673029182184333, "PEGINTRON": 0.5671550658538266, "PLAVIX": 0.6781535231954675, "SHINGRIX": 4.186539917986181, "SIMPONI": 0.5685921243995474, "SPIKEVAX": 0.1927818278371055, "SUBOXONE": 1.363090338528388, "SUTENT": 0.7104397727256503, "TOZINAMERAN": 0.7639532799102184, "VAXZEVRIA": 0.1455860458180758, "VIAGRA": 1.7064616208124217, "VOTRIENT": 1.123072732971172, "XELJANZ": 0.8134328469846897, "XOLAIR": 0.8159198664404028, "ZOSTAVAX": 17.039829755063238, "null": 1.113003047793681}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10672.json
new file mode 100644
index 00000000000..de4bb7eca2d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10672.json
@@ -0,0 +1 @@
+{"COMIRNATY": 6.75696843123994}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10673.json
new file mode 100644
index 00000000000..90fada2f889
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10673.json
@@ -0,0 +1 @@
+{"null": 0.9567157319567168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10674.json
new file mode 100644
index 00000000000..cd7a8adbc24
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10674.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.301818247471489}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10675.json
new file mode 100644
index 00000000000..57227cae3d0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10675.json
@@ -0,0 +1 @@
+{"CANNABIDIOL": 228.33166332942892, "COMIRNATY": 1.3489601426583913, "SPIKEVAX": 0.9968645138129736, "STELARA": 7.141751001225828, "VAXZEVRIA": 0.8191246295678126, "null": 0.4551111918531689}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10676.json
new file mode 100644
index 00000000000..45b570949be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10676.json
@@ -0,0 +1 @@
+{"null": 1.2394035855567789}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10677.json
new file mode 100644
index 00000000000..ab4b9812ffb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10677.json
@@ -0,0 +1 @@
+{"ANIDULAFUNGIN": 1236.0227957260513, "CASPOFUNGIN": 146.56999985542103, "CICLOSPORIN": 33.59176742256848, "CYTARABINE": 17.332703644595487, "TACROLIMUS": 118.72095024196096, "VORICONAZOLE": 79.74604688162609, "null": 0.2083924928186715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10678.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10678.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10679.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10679.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1068.json
index c461ba05104..24a6e131458 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1068.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1068.json
@@ -1 +1 @@
-{"XOLAIR": 73.89204220973382}
\ No newline at end of file
+{"CETROTIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10680.json
new file mode 100644
index 00000000000..a901d54aba0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10680.json
@@ -0,0 +1 @@
+{"MIDAZOLAM": 345.1395535746629, "null": 0.855331966490197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10681.json
new file mode 100644
index 00000000000..e9fb7473ac1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10681.json
@@ -0,0 +1 @@
+{"ABILIFY": 86.45314892553935, "ARIPIPRAZOLE": 398.4730397608223, "LATUDA": 19.77172888196404, "OLANZAPINE": 17.627249017661228, "ZYPREXA": 8.878148154916273, "null": 0.5246129474787077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10682.json
new file mode 100644
index 00000000000..51a1bbbc3f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10682.json
@@ -0,0 +1 @@
+{"null": 0.907624958157944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10683.json
new file mode 100644
index 00000000000..0bda661b89d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10683.json
@@ -0,0 +1 @@
+{"ABILIFY": 47.51730364406918, "ACLIDINIUM": 68.72433453293026, "ANORO": 3.9019599376997456, "APTIVUS": 116.30765672503898, "ARIPIPRAZOLE": 55.57949769033774, "BREXPIPRAZOLE": 192.80771390351524, "BUPRENORPHINE": 3.203582100184093, "CHAMPIX": 4.4376329733018025, "COMIRNATY": 0.0430762936799999, "CYMBALTA": 0.5574011565411511, "EPADERM": 237.7034715968642, "INVEGA": 26.52068628790617, "IVABRADINE": 36.06121745877247, "KEPPRA": 0.7882144804301762, "LACOSAMIDE": 3.3964395526113127, "LANTUS": 0.4501825738607604, "LATUDA": 37.88318525932536, "LURASIDONE": 57.35541437371493, "OLANZAPINE": 42.37773851107194, "PALIPERIDONE": 30.07224782992016, "PEGASYS": 1.5333474970827048, "PEGINTRON": 0.7430683565168708, "PREGABALIN": 5.0948052972801126, "RISPERIDONE": 11.156527561526175, "SIMPONI": 0.7614429492482007, "SPIKEVAX": 0.0324010556483937, "STELARA": 0.4782963335758155, "SUBOXONE": 0.8940292799565107, "SYCREST": 50.00330337169883, "TELMISARTAN": 6.0018915112044855, "TOZINAMERAN": 0.0888017367551974, "XEPLION": 108.64342338680372, "ZYPADHERA": 21.36373084332392, "ZYPREXA": 17.08547428508869, "null": 0.9156242273331174}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10684.json
new file mode 100644
index 00000000000..d0dc294e2fe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10684.json
@@ -0,0 +1 @@
+{"ABILIFY": 25.36363654563196, "CHAMPIX": 10.27620016105712, "ZYPREXA": 10.424357905123252, "null": 1.2745860877083632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10685.json
new file mode 100644
index 00000000000..9dc31e08c69
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10685.json
@@ -0,0 +1 @@
+{"GARDASIL": 37.88538870542823, "null": 2.7069926423357544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10686.json
new file mode 100644
index 00000000000..0b892a803d6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10686.json
@@ -0,0 +1 @@
+{"null": 0.8458147468898483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10687.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10687.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10688.json
new file mode 100644
index 00000000000..09143972c95
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10688.json
@@ -0,0 +1 @@
+{"FASLODEX": 17.580402697143196, "LANTUS": 4.982039519207997, "null": 1.8126386915509247}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10689.json
new file mode 100644
index 00000000000..5d68e76ed3a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10689.json
@@ -0,0 +1 @@
+{"null": 1.3319280567229237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1069.json
index 5d92b33c46c..bd8b509c94b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1069.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1069.json
@@ -1 +1 @@
-{"APIDRA": 2.705869704756, "AVAMYS": 20.24999798576366, "BUDESONIDE": 58.39619944542872, "CICLOSPORIN": 1.9458043156652616, "CLOPIDOGREL": 1.9219222167329129, "FASENRA": 8.6905144511659, "GLYCOPYRRONIUM": 49.41222420313562, "INSULIN": 3.9168804334622975, "IRBESARTAN": 14.168890113224784, "MEPOLIZUMAB": 19.54803941744244, "METHOTREXATE": 12.2320088189661, "NUCALA": 4.54511312955349, "OMALIZUMAB": 30.152529532280926, "XOLAIR": 51.41391733544492}
\ No newline at end of file
+{"null": 4.0041722347359805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10690.json
new file mode 100644
index 00000000000..895aba44e78
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10690.json
@@ -0,0 +1 @@
+{"null": 1.1724972826029354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10691.json
new file mode 100644
index 00000000000..8a3f040528d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10691.json
@@ -0,0 +1 @@
+{"ABATACEPT": 2.981251192311463, "ADALIMUMAB": 3.631928805263551, "AFINITOR": 0.5573956328515366, "AIMOVIG": 1.7435385632822382, "ANAKINRA": 2.4237926097515583, "APIDRA": 1.117200662636811, "APREMILAST": 6.610966849558594, "ARAVA": 2.7755781579301644, "ATRIPLA": 0.3467012070396122, "AUBAGIO": 3.404037373776133, "BUPRENORPHINE": 2.1693109145917133, "BYDUREON": 1.8296065143893785, "CELECOXIB": 2.841236451837871, "CIMZIA": 0.4602908876491429, "COMIRNATY": 0.7986712360678577, "COSENTYX": 4.0542397912876345, "CYMBALTA": 0.9807153353966328, "ELIQUIS": 1.4182718702668895, "ENBREL": 2.1274619356670703, "ENTRESTO": 0.9227972957431444, "FASLODEX": 13.594553438163487, "FORSTEO": 5.432031300962419, "GARDASIL": 0.3025042107136348, "HARVONI": 2.650120604321654, "HUMALOG": 1.1371544071875148, "IBRANCE": 1.6985553083893483, "INSULIN": 1.1102769306681006, "JANUMET": 1.932441785675928, "KEYTRUDA": 0.2538006363308659, "LANTUS": 1.6496590587570794, "LYRICA": 2.767075263913238, "MEPOLIZUMAB": 1.825655789974684, "METHOTREXATE": 1.0225460336440273, "MODERNA": 1.1482753283909146, "NUCALA": 0.8227570353258047, "PEGINTRON": 1.3041639753758307, "PLAVIX": 0.4200687184691591, "RITUXIMAB": 0.954530535313074, "SHINGRIX": 1.3904194861528154, "SIMPONI": 1.030349696317434, "SPIKEVAX": 0.5408552226291149, "SPINRAZA": 2.935158369290608, "STELARA": 1.023372599492442, "STRIBILD": 1.2105637499010438, "SUBOXONE": 0.9477893381041462, "SUTENT": 0.974768326105502, "TASIGNA": 1.26835092338274, "TOZINAMERAN": 1.1681064092457938, "TRUVADA": 0.3152598352011789, "VAXZEVRIA": 0.789115277065875, "VIAGRA": 1.0570290892165457, "XELJANZ": 3.385834904086282, "XTANDI": 0.5102449926378756, "ZOSTAVAX": 6.052431720095604, "null": 0.5390342761286316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10692.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10692.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10693.json
new file mode 100644
index 00000000000..d517e440426
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10693.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.111204105700866, "SPIKEVAX": 0.7671527403615622, "VAXZEVRIA": 0.8770635695986149, "null": 0.92819792113342}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10694.json
new file mode 100644
index 00000000000..a69846ea5de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10694.json
@@ -0,0 +1 @@
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10695.json
new file mode 100644
index 00000000000..f75499a0654
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10695.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1791888883120586, "null": 3.056610208609161}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10696.json
new file mode 100644
index 00000000000..c3272ecade2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10696.json
@@ -0,0 +1 @@
+{"null": 2.28908105644439}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10697.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10697.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10698.json
new file mode 100644
index 00000000000..d683bde6b50
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10698.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3057046848878571, "ELIQUIS": 12.972230427906274, "null": 0.5269630810145057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10699.json
new file mode 100644
index 00000000000..cfe14c110ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10699.json
@@ -0,0 +1 @@
+{"null": 1.893366189668725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/107.json
index 0ff9e50b8e4..71a1e382a44 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/107.json
@@ -1 +1 @@
-{"FORXIGA": 381.0232514944572, "JARDIANCE": 70.54379367038923}
\ No newline at end of file
+{"BIKTARVY": 60.87521138170389, "HUMALOG": 5.5316710068475805, "LYRICA": 7.895300222220611, "MICARDIS": 53.41508211971693, "STELARA": 4.154637204086062, "SUBOXONE": 9.392615948315417, "VIAGRA": 26.149745521403563, "XELJANZ": 2.914947536926745, "null": 1.2750423180924364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1070.json
index e625e967ca1..ffed2e44063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1070.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1070.json
@@ -1 +1 @@
-{"CELLCEPT": 7.952161995789375, "CICLOSPORIN": 9.82352114689494, "CYTARABINE": 6.98489893239978, "HIZENTRA": 36.27031361807778, "HUMAN": 42.224203467572615, "KESIMPTA": 47.53312550050819, "SOLIRIS": 10.986152632239996, "XOLAIR": 4.002424426005726}
\ No newline at end of file
+{"null": 0.8953782293383834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10700.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10700.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10701.json
new file mode 100644
index 00000000000..95d746da76a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10701.json
@@ -0,0 +1 @@
+{"null": 3.3885639655772475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10702.json
new file mode 100644
index 00000000000..f69cf73faa7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10702.json
@@ -0,0 +1 @@
+{"BEVACIZUMAB": 224.65920500806192, "null": 1.952709951052248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10703.json
new file mode 100644
index 00000000000..0e3f2a5bc2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10703.json
@@ -0,0 +1 @@
+{"null": 1.0567857957019913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10704.json
new file mode 100644
index 00000000000..547e99e524b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10704.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7109543928193183, "EYLEA": 14.616764495066128, "SIMPONI": 7.201748581646821, "SPIKEVAX": 0.4399341500943234, "TOZINAMERAN": 0.8537920975870242, "VAXZEVRIA": 0.4214607522150054, "null": 0.616935322213576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10705.json
new file mode 100644
index 00000000000..905a311828d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10705.json
@@ -0,0 +1 @@
+{"OPTIMARK": 243.49001473448632, "null": 0.3805458436018102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10706.json
new file mode 100644
index 00000000000..c5bb00a5cd0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10706.json
@@ -0,0 +1 @@
+{"ADCIRCA": 42.51443995325182, "AZATHIOPRINE": 11.451869142288906, "CELLCEPT": 4.633418496939563, "CICLOSPORIN": 10.620117258113632, "COMIRNATY": 0.2691616207381015, "HUMALOG": 1.1481438960470665, "ICLUSIG": 9.602887915914474, "IMATINIB": 21.810067991283336, "KEYTRUDA": 1.9088242156362891, "MYCOPHENOLATE": 11.16677317624642, "OFEV": 8.986190619908276, "OPSUMIT": 25.399559518120125, "OPTIMARK": 9.518087790306872, "PEMETREXED": 22.765918159140377, "REVATIO": 31.68006842856338, "SOLIRIS": 4.501496425232639, "SPIKEVAX": 0.1296827930488737, "TOZINAMERAN": 0.3554224485640957, "TRACLEER": 38.12374010520422, "XELJANZ": 1.4161144501519398, "null": 0.7077780013895092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10707.json
new file mode 100644
index 00000000000..faa6172baa6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10707.json
@@ -0,0 +1 @@
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10708.json
new file mode 100644
index 00000000000..cb6c931ede9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10708.json
@@ -0,0 +1 @@
+{"null": 0.5724744751027339}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10709.json
new file mode 100644
index 00000000000..5563a162e95
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10709.json
@@ -0,0 +1 @@
+{"null": 4.489626363644233}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1071.json
index 6b061223f3b..d0a9ceb831f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1071.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1071.json
@@ -1 +1 @@
-{"ADCIRCA": 54.19663242197809, "CICLOSPORIN": 3.202841931905586, "DEXAMETHASONE": 5.41268101783985, "null": 1.216852199072753}
\ No newline at end of file
+{"COMIRNATY": 0.0709308796507785, "LEVETIRACETAM": 20.13979989690805, "NEXAVAR": 5.940329626523916, "null": 3.2864250777030453}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10710.json
new file mode 100644
index 00000000000..5261f26c6c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10710.json
@@ -0,0 +1 @@
+{"TERIPARATIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10711.json
new file mode 100644
index 00000000000..b49973be1eb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10711.json
@@ -0,0 +1 @@
+{"null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10712.json
new file mode 100644
index 00000000000..32c71397287
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10712.json
@@ -0,0 +1 @@
+{"MODERNA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10713.json
new file mode 100644
index 00000000000..711d480407c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10713.json
@@ -0,0 +1 @@
+{"ADENURIC": 13.971331872928133, "ARAVA": 0.5952611926794981, "ATRIPLA": 0.6367567420453619, "BIKTARVY": 3.682927665137964, "COMIRNATY": 0.0495542251967757, "CYMBALTA": 10.160809921090328, "DULOXETINE": 3.96331662448424, "ENBREL": 1.792347943185544, "FORSTEO": 1.5287725602711133, "GARDASIL": 3.064880378955511, "KEPPRA": 0.948236329072814, "NAGLAZYME": 7.538732418272471, "NUTROPIN": 165.5105509865673, "OMNITROPE": 42.924190453972365, "SOMATROPIN": 87.56623486100816, "SPINRAZA": 396.9027946407125, "SUBOXONE": 1.7330009245101785, "TRUVADA": 0.5090671410741661, "XELJANZ": 1.4913448869574608, "ZOSTAVAX": 4.4098378184723135, "null": 1.6298971627051733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10714.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10714.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10715.json
new file mode 100644
index 00000000000..c2c7340122f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10715.json
@@ -0,0 +1 @@
+{"CHAMPIX": 1.0993505799706795, "CLOPIDOGREL": 1.0212458716226125, "COMIRNATY": 0.1984409654377284, "COSENTYX": 5.545766174096899, "ELIQUIS": 2.5690559127384467, "EUCREAS": 14.68221026310497, "FENTANYL": 2.5522562745149795, "GARDASIL": 0.9118974645414754, "HEXYON": 248.62180176241336, "HUMALOG": 1.4833221513258557, "IBRANCE": 2.134012404711612, "INFANRIX": 19.85438928934217, "KEPPRA": 0.829940435111662, "MMRVAXPRO": 28.134086092751165, "NUCALA": 5.725738890044616, "OMALIZUMAB": 11.26282197825315, "PEGASYS": 0.5430636696489894, "PEGINTRON": 1.4287912117385912, "PLAVIX": 0.8925822372745743, "PREVENAR": 19.608899318377503, "SHINGRIX": 1.488930909856378, "SPIKEVAX": 0.1244121965797001, "SUTENT": 1.006012345158626, "TOZINAMERAN": 0.9342943964754216, "XELJANZ": 1.7636584001753086, "XOLAIR": 4.281244513369621, "null": 0.9743731382701608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10716.json
new file mode 100644
index 00000000000..a07c39d5c47
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10716.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.1564542404636526, "BRIVIACT": 8.222162567088276, "CARBIDOPA": 12.740345407600287, "CHAMPIX": 1.4579157160055385, "COMIRNATY": 0.0805229233880239, "CYMBALTA": 1.1229293070401185, "FENTANYL": 1.2515565218919826, "GARDASIL": 1.080436195653211, "HEXYON": 68.83905875963742, "INFANRIX": 62.76401516082001, "KEPPRA": 3.907714341062616, "LATUDA": 6.0883371726773685, "LEVETIRACETAM": 1.6220860411223164, "MMRVAXPRO": 61.73822130358348, "NIMENRIX": 2.726265091401973, "OLANZAPINE": 0.9958498965347397, "PREVENAR": 33.50956357419441, "ROTATEQ": 30.956921983246534, "SPIKEVAX": 0.0474856862269884, "TAMIFLU": 6.345873868592912, "TOZINAMERAN": 0.5422824405435352, "VAXZEVRIA": 0.1048967055455176, "VIMPAT": 3.666126751812902, "ZYPREXA": 0.9517507564265614, "null": 2.386158053196459}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10717.json
new file mode 100644
index 00000000000..999ef43aac2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10717.json
@@ -0,0 +1 @@
+{"JARDIANCE": 136.33366938479966, "null": 0.1884785223932353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10718.json
new file mode 100644
index 00000000000..1e02e623a53
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10718.json
@@ -0,0 +1 @@
+{"null": 0.6378939197264512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10719.json
new file mode 100644
index 00000000000..a5c32395792
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10719.json
@@ -0,0 +1 @@
+{"null": 2.537626760976944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1072.json
index e2af78fd696..2088eca1019 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1072.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1072.json
@@ -1 +1 @@
-{"KESIMPTA": 222.44735195869603, "MEPOLIZUMAB": 66.63538729671635}
\ No newline at end of file
+{"ABACAVIR": 0.2095189246218707, "ABASAGLAR": 0.1449814317726139, "ABATACEPT": 1.3726880737322784, "ABEMACICLIB": 1.3461667595117086, "ABILIFY": 0.3659101190074922, "ABIRATERONE": 1.4861108050755276, "ABRAXANE": 0.3476220699714403, "ACLIDINIUM": 0.1786380370031905, "ACTOS": 0.7728339390253803, "ACTRAPID": 0.3398450873290985, "ADALIMUMAB": 0.903983182269582, "ADCIRCA": 1.2092452138676215, "ADEMPAS": 0.9890332223690186, "ADENURIC": 0.6310148604624702, "ADVAGRAF": 0.4496176265012094, "AERIUS": 0.7074585920253162, "AFINITOR": 1.198900950313385, "AFLIBERCEPT": 1.6986746877109735, "AGOMELATINE": 1.0591669004295856, "AIMOVIG": 0.4464570651645892, "ALDARA": 1.299269499722589, "ALEMTUZUMAB": 0.4242603631367102, "ALIMTA": 1.1717740189443266, "ALISKIREN": 1.625550193260453, "ALL": 0.405349552909861, "ALPELISIB": 0.3542374266078519, "ALYMSYS": 5.698201700647485, "AMBRISENTAN": 0.6356207307447586, "AMGEVITA": 2.3092256701979856, "AMIKACIN": 0.3180295265371445, "AMINOSALICYLIC": 0.7798881203098548, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10720.json
new file mode 100644
index 00000000000..d178fca2a77
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10720.json
@@ -0,0 +1 @@
+{"NEXAVAR": 49.05166207153078, "SUTENT": 9.508684115981488, "null": 0.8132120548405579}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10721.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10721.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10722.json
new file mode 100644
index 00000000000..f66868290a8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10722.json
@@ -0,0 +1 @@
+{"null": 2.6454992938449817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10723.json
new file mode 100644
index 00000000000..de7cf18c0cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10723.json
@@ -0,0 +1 @@
+{"null": 1.09168592872367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10724.json
new file mode 100644
index 00000000000..75046bdc120
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10724.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 136.08489480916026, "JARDIANCE": 35.88915790720246, "null": 0.3891738137008944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10725.json
new file mode 100644
index 00000000000..ae63dda66ba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10725.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 22.04026547274284, "null": 1.2542438995844267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10726.json
new file mode 100644
index 00000000000..fab03a7a666
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10726.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 0.8022665869716739, "TOZINAMERAN": 2.031257449974808, "VAXZEVRIA": 0.3506368982777229, "null": 1.3808040321566133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10727.json
new file mode 100644
index 00000000000..85134703d4c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10727.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1704080793589998, "JARDIANCE": 7.434550864430552, "PEGASYS": 2.8410989769345627, "null": 1.0904540749017009}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10728.json
new file mode 100644
index 00000000000..f185839f79a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10728.json
@@ -0,0 +1 @@
+{"null": 0.737530534340126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10729.json
new file mode 100644
index 00000000000..b6e99195e24
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10729.json
@@ -0,0 +1 @@
+{"null": 1.073920800929468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1073.json
index b25bd4656c3..8758d5e7cae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1073.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1073.json
@@ -1 +1 @@
-{"ARAVA": 2.2861965629979397}
\ No newline at end of file
+{"COMIRNATY": 1.2681237313464702, "COSENTYX": 1.6683686785558844, "CYMBALTA": 0.6629307309991193, "GARDASIL": 0.9709175620277088, "KEPPRA": 2.401378373691028, "LANTUS": 0.6829987819240362, "PEGINTRON": 1.2386596748241545, "SHINGRIX": 1.430532788050514, "SPIKEVAX": 0.8581384985579333, "STELARA": 1.3634163907249743, "TOZINAMERAN": 3.6379357678172055, "VAXZEVRIA": 3.1514848068731496, "VIAGRA": 3.332223315647417, "null": 0.6028865985492536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10730.json
new file mode 100644
index 00000000000..1888afa6c0e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10730.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.2434760957856823, "ARAVA": 0.3898151884774748, "AVAMYS": 9.666191985819763, "BUDESONIDE": 1.0803450561536685, "CAPECITABINE": 2.594722771394552, "COMIRNATY": 0.5443714897569768, "COSENTYX": 1.2253931686778727, "DEXAMETHASONE": 0.939185331097856, "ELIQUIS": 0.4063905237724919, "ENTRESTO": 1.4843534626214197, "FASENRA": 2.329724868962989, "FLUTICASONE": 16.436782612582842, "GARDASIL": 2.0593722454874515, "HUMIRA": 2.467111749239992, "HYDROCORTISONE": 2.770592022300437, "IBRANCE": 1.1590329789360276, "MEPOLIZUMAB": 24.72955207482545, "MMRVAXPRO": 1.5660206557195635, "NIMENRIX": 2.3283171001890066, "NUCALA": 12.060427134334642, "OFEV": 3.507581480832375, "OMALIZUMAB": 9.119354964688991, "OPSUMIT": 5.242248597347933, "PANTOPRAZOLE": 6.325350553613174, "SIMPONI": 2.2592287120582357, "SPIKEVAX": 0.4138718993242189, "STELARA": 0.6779329971447855, "SUTENT": 0.2717854490756862, "TOZINAMERAN": 1.7458222319946546, "TRACLEER": 2.364734917583493, "TWINRIX": 11.77671855157093, "UMECLIDINIUM": 23.8905267024696, "VAXZEVRIA": 0.5454148464361158, "XELJANZ": 2.321015128880997, "XOLAIR": 4.112645436382335, "ZOSTAVAX": 8.261111908794483, "null": 0.7924123261461494}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10731.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10731.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10732.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10732.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10733.json
new file mode 100644
index 00000000000..59fcb4d1c66
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10733.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 48.89579685646586, "null": 0.3992861189850491}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10734.json
new file mode 100644
index 00000000000..de6c221bf16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10734.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4653321229157122, "VAXZEVRIA": 0.1655369989183441, "null": 3.664221900743241}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10735.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10735.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10736.json
new file mode 100644
index 00000000000..1b1072d5b68
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10736.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 15.707807254646918, "BUPRENORPHINE": 5.302241692920689, "COMIRNATY": 0.4502240212537756, "ENBREL": 3.460503818133671, "IRESSA": 13.181554866463816, "SPIKEVAX": 0.1805096414568059, "VAXZEVRIA": 0.2240454316172297, "ZOSTAVAX": 14.316599116710144, "null": 0.8317978382888863}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10737.json
new file mode 100644
index 00000000000..c4d47c08dd3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10737.json
@@ -0,0 +1 @@
+{"COSENTYX": 21.604151473259176, "ELIQUIS": 2.947350355040885, "ZOSTAVAX": 60.66986636655824, "null": 0.6051768785859165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10738.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10738.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10739.json
new file mode 100644
index 00000000000..89ed5fd7cce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10739.json
@@ -0,0 +1 @@
+{"ADCETRIS": 35.24043607138998, "AFINITOR": 8.531098187607562, "ASPARAGINASE": 11.1642737739218, "AZACITIDINE": 5.261337700330448, "BEVACIZUMAB": 2.5120521640890714, "BLINATUMOMAB": 16.436010274694794, "BORTEZOMIB": 6.2689706562796434, "BOSULIF": 28.95057316394313, "BRAFTOVI": 29.646028287291344, "BUSULFAN": 5.628622856582986, "CAELYX": 3.849320436811404, "CAPECITABINE": 2.524240467269103, "CARMUSTINE": 38.05057265653156, "CHLORMETHINE": 223.8543905293455, "CICLOSPORIN": 0.8393420646196145, "CYTARABINE": 11.658445398650723, "DEXAMETHASONE": 2.055241307447792, "DOCETAXEL": 7.364305891823765, "DOXORUBICIN": 25.89722789329935, "FASLODEX": 3.716338760678712, "FULVESTRANT": 2.632643487887668, "GLIVEC": 22.180719621427308, "IBRANCE": 30.31386584773108, "IMATINIB": 30.249790175017008, "INLYTA": 21.67308190083684, "JAKAVI": 75.70693572238679, "KISQALI": 4.840285452898643, "KYMRIAH": 20.21401009052694, "MEKINIST": 12.995840973245516, "METHOTREXATE": 2.2649894858586084, "NILOTINIB": 36.12489304745866, "NOT": 3.2761814822481186, "PACLITAXEL": 6.264088195099037, "RITUXIMAB": 7.7101523300463395, "RUXOLITINIB": 125.6648281816963, "SUTENT": 18.214793728660045, "TASIGNA": 36.742059137578224, "THIOTEPA": 28.662096829500527, "VOTRIENT": 4.516309952548652, "XALKORI": 10.644337466105158, "null": 0.2698755453387035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1074.json
index 593ad63ad6b..8dc465266d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1074.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1074.json
@@ -1 +1 @@
-{"AVAMYS": 94.8730509888974}
\ No newline at end of file
+{"null": 1.2792279924443763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10740.json
new file mode 100644
index 00000000000..960ab9b79f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10740.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 2.6922832908971093, "CANAKINUMAB": 471.6832882559841, "COMIRNATY": 0.0448719114126625, "HYDROCORTISONE": 9.399777387830484, "IPILIMUMAB": 57.4108844572086, "KEYTRUDA": 34.77567618464951, "OPDIVO": 214.4315939123931, "PEMBROLIZUMAB": 18.56480101248293, "RITONAVIR": 391.7042329091548, "null": 0.4946407080495595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10741.json
new file mode 100644
index 00000000000..0ab499939e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10741.json
@@ -0,0 +1 @@
+{"NEXAVAR": 12.399022293355722, "STIVARGA": 25.820594936627167, "null": 0.7551461450545476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10742.json
new file mode 100644
index 00000000000..6db96667366
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10742.json
@@ -0,0 +1 @@
+{"null": 1.8996485445655216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10743.json
new file mode 100644
index 00000000000..0f269389f8f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10743.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 45.73791221897104, "null": 1.9262324314581003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10744.json
new file mode 100644
index 00000000000..019fac41096
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10744.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 776.0485639878335, "CICLOSPORIN": 14.842200416393604, "CYTARABINE": 29.495923097894487, "DOXORUBICIN": 28.64619921081292, "null": 0.079058206007433}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10745.json
new file mode 100644
index 00000000000..21ec166136c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10745.json
@@ -0,0 +1 @@
+{"AUBAGIO": 89.40403672073305, "BETAFERON": 75.64917814063908, "FAMPYRA": 421.45583356061866, "KESIMPTA": 100.80460411597666, "PLEGRIDY": 62.94658911090108, "null": 0.1546444249720887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10746.json
new file mode 100644
index 00000000000..6aec15632e4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10746.json
@@ -0,0 +1 @@
+{"ROTATEQ": 137.78317015243871, "VAXZEVRIA": 0.74191024401447, "ZOSTAVAX": 80.56195370986886, "null": 1.057820449923689}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10747.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10747.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10748.json
new file mode 100644
index 00000000000..75d66d40066
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10748.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.8015012765837362, "ARAVA": 0.4354403119095186, "AVAMYS": 63.03697584766921, "BENLYSTA": 3.135167868643157, "BENRALIZUMAB": 13.582347447204342, "BUDESONIDE": 2.8561394821655317, "CHOLESTAGEL": 128.6519703463677, "CICLOSPORIN": 0.5843087099652986, "COMIRNATY": 0.3700968713943036, "COSENTYX": 3.034212168069077, "CYMBALTA": 0.3727661009916327, "ELIQUIS": 0.3773347241441941, "ENBREL": 0.8086238381274315, "ESBRIET": 2.4713793777075663, "FASENRA": 8.826802659397945, "FLUTICASONE": 12.729734709100953, "IBRANCE": 0.9376612764519248, "INCRUSE": 5.714809058740615, "JARDIANCE": 1.1719703939988015, "KAFTRIO": 6.903666666842547, "LANTUS": 0.7165801959826377, "MEPOLIZUMAB": 6.83391463863827, "NAGLAZYME": 15.197310440512474, "NUCALA": 11.178679621059947, "OMALIZUMAB": 8.034071285506926, "OPSUMIT": 2.124539085548492, "RELVAR": 14.596052652349638, "REMICADE": 6.028913191362397, "SPIKEVAX": 0.4415649374616535, "SPINRAZA": 6.885173133584046, "STELARA": 0.5558075134970821, "SUTENT": 1.1485420764002214, "SYNAGIS": 4.205386222193698, "TOZINAMERAN": 0.6204383932553509, "TRELEGY": 11.236796371504065, "VAXZEVRIA": 0.2611824977720514, "XELJANZ": 2.0135399321394467, "XOLAIR": 4.859287380261092, "null": 1.0336084014808695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10749.json
new file mode 100644
index 00000000000..61f302d7d4d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10749.json
@@ -0,0 +1 @@
+{"ABILIFY": 25.48518799739108, "AIMOVIG": 3.2698808619550257, "AMBROXOL": 133.3674006465891, "AMLODIPINE": 111.98748844841803, "ANAGRELIDE": 29.8445940125878, "ARIPIPRAZOLE": 15.829448250433533, "ASENAPINE": 18.927634474977687, "BOTULINUM": 78.7743295756959, "BRINTELLIX": 2.305000806658024, "BRIVIACT": 6.363103093538912, "BUPIVACAINE": 4.9085230381071945, "BUPRENORPHINE": 5.069272311040873, "CAFFEINE": 80.51341514140996, "CANNABIDIOL": 9.526209467297024, "CARIPRAZINE": 28.993508603164717, "CHAMPIX": 0.5726928667898739, "CIRCADIN": 5.800682164551576, "COMIRNATY": 0.0867303287716394, "CYMBALTA": 1.5635576718020066, "DEXAMETHASONE": 0.7240112310795128, "DULOXETINE": 4.796971914906846, "EPIDYOLEX": 45.62015425726177, "ESOMEPRAZOLE": 4.0976809266558245, "FENTANYL": 6.113759462872155, "FYCOMPA": 2.2902415693451306, "IBUPROFEN": 0.506536831007114, "INVEGA": 9.30208094922216, "KEPPRA": 2.189798969438564, "LACOSAMIDE": 5.622788111011199, "LATUDA": 3.95296038508841, "LEVETIRACETAM": 6.220428126001628, "LEVOFLOXACIN": 39.62427969219826, "LOXAPINE": 14.53558252909778, "LURASIDONE": 18.28555559926985, "LYRICA": 3.2076871985432827, "MIDAZOLAM": 7.711292703832431, "NALOXONE": 20.535025536120216, "OLANZAPINE": 15.904715237993514, "OXYBUTYNIN": 4.30290665048088, "PREGABALIN": 5.433182875904223, "PROPRANOLOL": 2.45687905049138, "RISPERIDONE": 16.58734862341142, "SPIKEVAX": 0.0713903664808625, "SPIRONOLACTONE": 2.249928136106992, "SUBOXONE": 1.0761954925645505, "SUFENTANIL": 4.0074381768675975, "SYCREST": 38.9396529498552, "TOZINAMERAN": 0.0978577280827548, "VALDOXAN": 9.698695654328173, "VAXZEVRIA": 0.0713695421290021, "VIMPAT": 2.979379989058401, "XOLAIR": 0.4570844257561567, "XYREM": 4.006303483220632, "ZYPADHERA": 106.64327216150753, "ZYPREXA": 7.796374294609893, "null": 1.622238913500608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1075.json
index 44e5f7a149e..1629ee5dc95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1075.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1075.json
@@ -1 +1 @@
-{"JARDIANCE": 30.41091522748447}
\ No newline at end of file
+{"ABACAVIR": 11.18705619156061, "ABATACEPT": 2.469495432065034, "ABILIFY": 1.6103280370618764, "ACLIDINIUM": 16.034088047566755, "ACTOS": 0.5004678665765583, "ADALIMUMAB": 1.881153283458879, "ADCIRCA": 0.5529654752866862, "ADEMPAS": 0.3658401466843765, "AERIUS": 1.045581939864633, "AFINITOR": 0.1594300611576892, "AIMOVIG": 0.4425940850967076, "ALEMTUZUMAB": 0.4008881586348263, "ALENDRONATE": 9.637413100481346, "AMINOSALICYLIC": 0.5490899579777668, "ANORO": 9.535597473530563, "ANTIBIOTICS": 1.20258615354141, "ANTIHYPERTENSIVES": 5.792623423146339, "APIDRA": 0.1281151104765311, "APIXABAN": 10.182349875973024, "APREMILAST": 0.440677095815174, "APREPITANT": 1.4584316995445814, "ARANESP": 0.5420745686387158, "ARAVA": 0.5229600627129907, "ARIPIPRAZOLE": 0.33453389490379, "ASPARAGINASE": 0.4125778498808769, "ATRIPLA": 0.0068417154724529, "AUBAGIO": 0.3256414827326859, "AVAMYS": 14.69451177993974, "AVANDIA": 0.1667476253310229, "AZATHIOPRINE": 1.323100782370459, "AZOPT": 9.995585176547452, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10750.json
new file mode 100644
index 00000000000..3d12808aea6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10750.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10751.json
new file mode 100644
index 00000000000..556b0c0ec3b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10751.json
@@ -0,0 +1 @@
+{"null": 0.9062558297406124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10752.json
new file mode 100644
index 00000000000..b18193cda79
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10752.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.2092517544568804, "null": 0.5079113140053844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10753.json
new file mode 100644
index 00000000000..6e3b47423e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10753.json
@@ -0,0 +1 @@
+{"NEVANAC": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10754.json
new file mode 100644
index 00000000000..e852f7d99a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10754.json
@@ -0,0 +1 @@
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0.4559820883165836, "SHINGRIX": 0.2700937981467852, "SIFROL": 0.2625827124926281, "SILDENAFIL": 0.3499016903188492, "SILGARD": 1.9627196115713004, "SIMEPREVIR": 1.1011113197375495, "SIMPONI": 0.2546352570082975, "SOFOSBUVIR": 1.2034465595321326, "SOLIRIS": 1.1083213965739205, "SOMATROPIN": 0.934921180479867, "SOVALDI": 0.8003537875619058, "SPIKEVAX": 0.3078441858370617, "SPINRAZA": 1.0021905980939378, "SPRYCEL": 0.3410538923707011, "STALEVO": 0.4765869992666732, "STELARA": 0.4267200190471706, "STIVARGA": 0.124163627027844, "STRIBILD": 0.0664767173187238, "SUBOXONE": 2.557123529439152, "SUTENT": 0.4344264700271973, "SYCREST": 1.4765282697855913, "SYNAGIS": 2.067905274033656, "SYNFLORIX": 2.5735260394938924, "TACROLIMUS": 0.6752058328831672, "TAGRISSO": 0.3622449948924978, "TAMIFLU": 4.228074138257799, "TASIGNA": 0.1726574896369308, "TECFIDERA": 1.0458597750757503, "TELMISARTAN": 0.3234950505715751, "TEMODAL": 2.105077562087981, "TEMOZOLOMIDE": 2.1609611552650967, "THALIDOMIDE": 0.1871964897032316, "TIVICAY": 0.9348091723347206, "TORISEL": 0.7021148212009088, "TOUJEO": 0.5726513337100536, "TOVIAZ": 0.1979249187401943, "TOZINAMERAN": 0.753106939860305, "TRACLEER": 0.3082115750621001, "TRELEGY": 0.2865933075046493, "TREMFYA": 0.2739488578809836, "TRIUMEQ": 0.4486545912907669, "TRULICITY": 0.1160734864683099, "TRUVADA": 0.0330511508861163, "TWINRIX": 0.9885723748857264, "TYSABRI": 1.3971133857205846, "UNKNOWN": 1.7837432198691, "UNSPECIFIED": 0.6607527898228925, "VALDOXAN": 1.889291583943636, "VARENICLINE": 0.6614485790526383, "VARICELLA": 7.04305611684988, "VAXZEVRIA": 0.3468285128042388, "VELTASSA": 0.2086321316293831, "VENETOCLAX": 0.1942060383962743, "VFEND": 0.984175290521694, "VIAGRA": 0.6252518777033665, "VICTOZA": 0.3853816762880164, "VIGABATRIN": 14.971241000192276, "VIMPAT": 16.70242083141531, "VIREAD": 0.1346428066039349, "VORICONAZOLE": 0.634442637477731, "VOTRIENT": 0.7008175017165928, "XALKORI": 0.4680439515655078, "XARELTO": 0.2491966094447095, "XELJANZ": 0.1591338436600286, "XELODA": 0.2121410226169991, "XOLAIR": 0.477874211327731, "XTANDI": 2.360950347388388, "XYREM": 1.6387849970579285, "YERVOY": 0.2560809744731877, "YESCARTA": 0.7900389067104772, "ZAVESCA": 3.436587217212807, "ZELBORAF": 0.4241000145382302, "ZEPATIER": 0.6086772997513741, "ZINBRYTA": 1.1235438174098582, "ZONEGRAN": 8.947587382112076, "ZONISAMIDE": 6.66631430307889, "ZOSTAVAX": 0.2564798101481219, "ZYPADHERA": 0.5302010298325185, "ZYPREXA": 2.3216849268422517, "null": 2.4885244474962858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10755.json
new file mode 100644
index 00000000000..692303e5306
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10755.json
@@ -0,0 +1 @@
+{"null": 2.058588848931302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10756.json
new file mode 100644
index 00000000000..6110acdc030
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10756.json
@@ -0,0 +1 @@
+{"BRIVIACT": 91.35430651773312, "KEPPRA": 29.669829482621356, "LACOSAMIDE": 71.11065700603598, "LEVETIRACETAM": 73.28533167714178, "VIMPAT": 40.73193805559014, "null": 1.2001712398089928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10757.json
new file mode 100644
index 00000000000..3ef84b707c1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10757.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2489897554258009, "CYMBALTA": 1.427336124834328, "FENTANYL": 4.783206913372855, "GARDASIL": 13.079876394642437, "MENVEO": 37.53545852842799, "MIDAZOLAM": 24.6534542718135, "PEGASYS": 1.2573761403867232, "SPIKEVAX": 0.9996993304691651, "TOZINAMERAN": 0.9013248773498722, "VAXZEVRIA": 0.1830617054537267, "null": 1.4677706092765233}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10758.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10758.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10759.json
new file mode 100644
index 00000000000..35d7f0fe978
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10759.json
@@ -0,0 +1 @@
+{"null": 1.1414082821232734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1076.json
index ab621d7d809..442eb0cd164 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1076.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1076.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 20.42274415744563, "HUMALOG": 23.709868522952835, "INSULIN": 47.96976614974731, "LANTUS": 5.649699182692904}
\ No newline at end of file
+{"COMIRNATY": 0.9983325294777736, "GARDASIL": 30.20561878252772, "null": 0.9422645365230662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10760.json
new file mode 100644
index 00000000000..e24d1ffb031
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10760.json
@@ -0,0 +1 @@
+{"SUBOXONE": 65.30087065203118, "null": 1.405459086813505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10761.json
new file mode 100644
index 00000000000..a28e12ed0ef
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10761.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 5.302241692920689, "LEVETIRACETAM": 4.855196571912353, "OLANZAPINE": 7.2479894367861615, "ROTATEQ": 16.760705427012635, "SUBOXONE": 40.35611551603176, "SYNAGIS": 41.05370331781002, "ZYPREXA": 3.9440043436217342, "null": 2.621342160399399}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10762.json
new file mode 100644
index 00000000000..e631993b193
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10762.json
@@ -0,0 +1 @@
+{"null": 0.8747763506310584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10763.json
new file mode 100644
index 00000000000..7f47469d89d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10763.json
@@ -0,0 +1 @@
+{"BEXSERO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10764.json
new file mode 100644
index 00000000000..e19f85d76be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10764.json
@@ -0,0 +1 @@
+{"CHAMPIX": 7.014420232136416, "COMIRNATY": 0.1351104568719022, "GARDASIL": 3.197060104500168, "ZYPREXA": 7.115552077342087, "null": 3.7091436141765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10765.json
new file mode 100644
index 00000000000..1d979d302bd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10765.json
@@ -0,0 +1 @@
+{"null": 3.015891500848607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10766.json
new file mode 100644
index 00000000000..b8de3e15931
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10766.json
@@ -0,0 +1 @@
+{"COSENTYX": 65.08674238896936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10767.json
new file mode 100644
index 00000000000..aa8b4405a2e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10767.json
@@ -0,0 +1 @@
+{"ABILIFY": 6.789115383444483, "ARIPIPRAZOLE": 4.177068969358874, "BRINTELLIX": 6.344522301858557, "BRIVIACT": 18.1784230792798, "BUPRENORPHINE": 5.28017772800524, "CHAMPIX": 4.324109170815182, "CYMBALTA": 4.050496948765362, "FYCOMPA": 9.94347716623241, "GARDASIL": 0.8645310633930986, "IBUPROFEN": 1.735968403021432, "INVEGA": 122.61966924730778, "KAFTRIO": 6.2895820190888365, "KEPPRA": 8.272991553059118, "LATUDA": 15.265871679827743, "LEVETIRACETAM": 4.109508004727169, "OLANZAPINE": 7.411951188836761, "PEGASYS": 1.2968410585849846, "PEGINTRON": 1.22228486044306, "RISPERIDONE": 19.716546210210144, "STELARA": 0.7863445186978385, "SUBOXONE": 1.297866174985232, "SYMTUZA": 50.20958343048842, "TAMIFLU": 4.547461525569352, "ZYPREXA": 4.659190558155582, "null": 3.299560416108464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10768.json
new file mode 100644
index 00000000000..ef3894710c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10768.json
@@ -0,0 +1 @@
+{"null": 3.708418929425682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10769.json
new file mode 100644
index 00000000000..6e48b53f6a7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10769.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.7090519438833733, "ALLI": 198.9899244718566, "ARIPIPRAZOLE": 2.885631009687697, "BRINTELLIX": 15.49325200341054, "CHAMPIX": 34.66549004350117, "COMIRNATY": 0.0366801154857372, "CYMBALTA": 4.199111774155105, "DULOXETINE": 10.118283643206013, "KEPPRA": 3.3909489643184094, "LATUDA": 25.60733161160183, "OLANZAPINE": 8.086737669676035, "PEGASYS": 5.67433429611298, "SAXENDA": 5.762730828408215, "ZYPREXA": 4.0223846981473885, "null": 1.971863198990724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1077.json
index 644bfce6f5d..89fb5347bec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1077.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1077.json
@@ -1 +1 @@
-{"COVID19": 7.9770953345728195}
\ No newline at end of file
+{"ACLIDINIUM": 1026.0800915136883, "ANORO": 45.98258184337311, "AVAMYS": 78.84566730676038, "CANAGLIFLOZIN": 383.0106498809373, "ENTRESTO": 18.042183582852, "INVOKANA": 89.93854887139695, "null": 0.3077676668574624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10770.json
new file mode 100644
index 00000000000..c83f73740af
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10770.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 8.770424244158582, "CYMBALTA": 1.5195648964810893, "IBUPROFEN": 9.591364760801609, "OLANZAPINE": 3.218984942309599, "SILDENAFIL": 20.351309600838626, "TESTOSTERONE": 58.86283737018609, "TREMFYA": 14.053218824769942, "null": 4.04418055934606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10771.json
new file mode 100644
index 00000000000..af86c3ec673
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10771.json
@@ -0,0 +1 @@
+{"null": 5.515027766857728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10772.json
new file mode 100644
index 00000000000..f19a0417b2c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10772.json
@@ -0,0 +1 @@
+{"RINVOQ": 281.32331418923536, "null": 0.8812240998721171}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10773.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10773.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10774.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10774.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10775.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10775.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10776.json
new file mode 100644
index 00000000000..c6945765257
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10776.json
@@ -0,0 +1 @@
+{"null": 4.084932439899535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10777.json
new file mode 100644
index 00000000000..688d73b736e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10777.json
@@ -0,0 +1 @@
+{"null": 9.16248295172628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10778.json
new file mode 100644
index 00000000000..c39877d6178
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10778.json
@@ -0,0 +1 @@
+{"null": 16.45057445449898}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10779.json
new file mode 100644
index 00000000000..7248288c5fd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10779.json
@@ -0,0 +1 @@
+{"VIAGRA": 828.1244651341824}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1078.json
index bed267fff90..c23c6645d54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1078.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1078.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.4794232146282837, "ARAVA": 127.69965101505848, "CYMBALTA": 1.4744946877078322}
\ No newline at end of file
+{"AVAMYS": 15.095260043360764, "BENLYSTA": 1.0658970927586664, "BUDESONIDE": 5.275316004564502, "COMIRNATY": 0.3976342230101405, "ELIQUIS": 0.3902187225109363, "FASENRA": 17.028105715046745, "FLUTICASONE": 13.754159925507574, "FORSTEO": 0.7367424371640929, "GLYCOPYRRONIUM": 14.8907051112214, "HYDROCORTISONE": 2.59486931973495, "LANTUS": 0.3087173266003604, "LEVOFLOXACIN": 0.9034964155580972, "MEPOLIZUMAB": 25.5719103781166, "NUCALA": 56.59210700077772, "OMALIZUMAB": 3.383708469849333, "RELVAR": 30.24820815684373, "SIMPONI": 0.6356576632633272, "SPIKEVAX": 0.1855651739099639, "VAXZEVRIA": 0.1612900177379748, "XOLAIR": 15.189563851014636, "null": 2.7739045648684826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10780.json
new file mode 100644
index 00000000000..ace0291cabf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10780.json
@@ -0,0 +1 @@
+{"JARDIANCE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10781.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10781.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10782.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10782.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10783.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10783.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10784.json
new file mode 100644
index 00000000000..1401f952de0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10784.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 58.65950028536193, "null": 0.5499397136836294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10785.json
new file mode 100644
index 00000000000..ab25c967b08
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10785.json
@@ -0,0 +1 @@
+{"ELIQUIS": 5.741934244568681, "null": 1.490621280116195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10786.json
new file mode 100644
index 00000000000..ed0aca61250
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10786.json
@@ -0,0 +1 @@
+{"OPDIVO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10787.json
new file mode 100644
index 00000000000..b3a6f319d0b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10787.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7980097088688988, "SPIKEVAX": 1.4518705956594522, "TOZINAMERAN": 2.2627561038441497, "VAXZEVRIA": 1.6916199569166748, "null": 0.8561397251200334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10788.json
new file mode 100644
index 00000000000..2686852949b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10788.json
@@ -0,0 +1 @@
+{"AIMOVIG": 0.987181980432873, "CHAMPIX": 0.5789615958927697, "CHOLESTAGEL": 100.13469470087064, "CLOPIDOGREL": 0.4244197606926003, "COMIRNATY": 1.9621554387458924, "COSENTYX": 1.455672866515717, "ELIQUIS": 0.231747745834896, "GARDASIL": 1.170241482109222, "HUMIRA": 1.0256163603755877, "IBRANCE": 0.5205345646963097, "PEGASYS": 0.2256920972411077, "SPIKEVAX": 0.8332884948633158, "SUTENT": 0.6190893229788962, "TOZINAMERAN": 1.8164728199427052, "TRELEGY": 1.2844105016950529, "VAXZEVRIA": 0.4947779836260553, "XELJANZ": 0.6283174658256124, "XOLAIR": 3.1418626587713843, "null": 1.7477698043477503}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10789.json
new file mode 100644
index 00000000000..1d377069068
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10789.json
@@ -0,0 +1 @@
+{"BENRALIZUMAB": 35.266687081121624, "BRILIQUE": 4.636872439740137, "CAELYX": 11.278713760496354, "CHAMPIX": 1.1455992437865046, "COMIRNATY": 1.862726154955548, "DEXAMETHASONE": 2.1585048070201607, "MEPOLIZUMAB": 3.972355871496021, "NUCALA": 5.053346913759841, "SPIKEVAX": 1.5148599588026954, "VAXZEVRIA": 0.7546276796332055, "null": 1.2542909228430068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1079.json
index 6afab84bc5a..0f2425e82e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1079.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1079.json
@@ -1 +1 @@
-{"AFINITOR": 1.8650326684724303, "APIXABAN": 1.3969667542714668, "APTIVUS": 123.41799091410346, "ARANESP": 1.612505111311657, "CAPECITABINE": 2.862059606200239, "CELLCEPT": 4.29736613128196, "CLOPIDOGREL": 3.9772751489881975, "ELIQUIS": 3.288142790445019, "EMPAGLIFLOZIN": 10.72022974252701, "ENTRESTO": 3.172002068758169, "ENTYVIO": 4.058160068064939, "FAMPYRA": 4.1191062719808205, "FORSTEO": 1.2118858453789088, "GARDASIL": 1.7802021366562537, "HUMIRA": 2.1522918297716678, "IBRANCE": 3.563610610790532, "IRON": 15.697507529992688, "JAKAVI": 1.7879495213462755, "METHOTREXATE": 4.2397270109538825, "MICARDIS": 5.281402190095919, "OMALIZUMAB": 18.139878914935984, "OPSUMIT": 6.606844225701386, "OZEMPIC": 44.71847159120878, "PEGASYS": 1.2925396601917247, "PEGINTRON": 1.2234472240698533, "PLAVIX": 2.2096870435447684, "REVATIO": 3.646606378037705, "RINVOQ": 3.957637095227268, "SEMAGLUTIDE": 53.70211449605184, "SIMPONI": 1.626010245157894, "SOLIRIS": 1.3646688897400343, "STELARA": 1.2417465784979511, "SUTENT": 1.1714663345150618, "TRACLEER": 2.378110733013505, "XELJANZ": 3.3957232138493585}
\ No newline at end of file
+{"COMIRNATY": 0.3637353763018923, "GARDASIL": 2.9041705346459343, "HUMALOG": 2.738751409687289, "SPIKEVAX": 0.1575105821454598, "ZOSTAVAX": 19.59732373409444, "null": 2.381702405050988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10790.json
new file mode 100644
index 00000000000..9d0b42a21e9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10790.json
@@ -0,0 +1 @@
+{"APIXABAN": 774.829817809709, "COMIRNATY": 0.1058532530253436, "ELIQUIS": 9.412189705513464, "ESOMEPRAZOLE": 16.791189989164966, "SPIKEVAX": 0.1330916534351157, "TOZINAMERAN": 0.6665835592094503, "VAXZEVRIA": 0.3779526488125476, "null": 0.20994688521434}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10791.json
new file mode 100644
index 00000000000..5cbb2a0e5db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10791.json
@@ -0,0 +1 @@
+{"CHAMPIX": 0.3589199135096731, "COMIRNATY": 0.981640865730885, "CYMBALTA": 0.3103989456204243, "ELIQUIS": 0.2306819832075143, "GARDASIL": 0.2659901069649407, "HYDROCORTISONE": 3.321162176162777, "IBRANCE": 0.614877736118154, "NEXAVAR": 0.6248114847373354, "OCRELIZUMAB": 3.63719829816344, "OPTIMARK": 1.6687339907962622, "PEGASYS": 0.6393653636180365, "SHINGRIX": 2.1294868268329803, "SPIKEVAX": 1.6651856521397077, "STELARA": 1.595447133642288, "SUTENT": 1.5045682265546043, "TOZINAMERAN": 18.042865623923763, "VAXZEVRIA": 3.106636118846528, "XOLAIR": 0.4363746560885874, "ZOSTAVAX": 1.0899607605015749, "null": 0.2147568841051714}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10792.json
new file mode 100644
index 00000000000..70bd16465a7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10792.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 1.0342309940266032, "ARAVA": 2.3424727231521256, "ENBREL": 5.337695048312534, "HUMIRA": 3.842116761482624, "IBRANCE": 2.269953599690398, "NUCALA": 4.192510089486671, "OMALIZUMAB": 69.57283026640259, "XELJANZ": 74.7837466638745, "XOLAIR": 6.485839434529864, "null": 1.1822811271349978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10793.json
new file mode 100644
index 00000000000..5e00ca263ec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10793.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.0795894343016563, "SPIKEVAX": 0.7333500018659073, "VAXZEVRIA": 0.2939142770879776, "null": 1.3548480415898183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10794.json
new file mode 100644
index 00000000000..08c0fe9c452
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10794.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.4316670289013853, "ADENURIC": 2.840218629350158, "AFINITOR": 0.2427904324755254, "AIMOVIG": 0.453981312475649, "APIDRA": 1.1079691862684653, "AUBAGIO": 4.23107814163332, "BETAFERON": 2.8814928679209904, "BUPIVACAINE": 2.04410626565695, "BUPRENORPHINE": 0.6317458457197519, "CHAMPIX": 0.6672191074821134, "CICLOSPORIN": 0.8054142717152907, "CLOPIDOGREL": 0.209239968318633, "COMBIVIR": 1.2414436341198405, "COMIRNATY": 2.0188416693886952, "COSENTYX": 0.2137846247185084, "CYMBALTA": 23.24487633384121, "ELIQUIS": 0.1902402915957245, "ENBREL": 0.3942465502314754, "FAMPYRA": 3.253051744971218, "FASLODEX": 0.809932351242054, "FENTANYL": 1.1849697390867489, "FORSTEO": 0.3779137561075779, "FULVESTRANT": 0.9646062703646496, "GARDASIL": 5.816793233418414, "IBRANCE": 0.1442852657294317, "JANUVIA": 0.3174982492348443, "JARDIANCE": 0.1803398419433567, "KEPPRA": 0.320734717686549, "KESIMPTA": 3.839782968214692, "KEYTRUDA": 0.1417509386346718, "LANTUS": 0.2018985014716392, "LEMTRADA": 1.9762667881781744, "LEVETIRACETAM": 0.6761873579501367, "LEVOFLOXACIN": 0.8138799240529699, "LYRICA": 0.4598594852072812, "MAVENCLAD": 2.6646438776500165, "MEPOLIZUMAB": 0.3990784856312539, "MMRVAXPRO": 0.3314473048213968, "OMALIZUMAB": 0.3953617446514236, "PEGASYS": 0.3430853996651105, "PEGINTRON": 0.2109369042821273, "PLAVIX": 0.1635268115188557, "PLEGRIDY": 1.700376917033518, "RASILEZ": 1.678252585974623, "ROACTEMRA": 0.5175860800394824, "SHINGRIX": 1.2410315242776897, "SIMPONI": 0.7937059746869177, "SPIKEVAX": 0.9710513743351472, "SPINRAZA": 1.1425940785234052, "STELARA": 0.3795652015224629, "SUBOXONE": 0.2778873806511324, "SUTENT": 0.1178513409940535, "TAMIFLU": 0.5830737174456883, "TOZINAMERAN": 0.8816665050110645, "TWINRIX": 6.242004318535405, "VAXZEVRIA": 1.4145012799689891, "VFEND": 0.6295271317362591, "XELJANZ": 0.2253536213217224, "XELODA": 2.5989980533656034, "XOLAIR": 0.3940435918836627, "ZOSTAVAX": 0.2660529138148675, "ZYPREXA": 0.5399949379257899, "null": 0.6492254866051264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10795.json
new file mode 100644
index 00000000000..b57b9bf03b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10795.json
@@ -0,0 +1 @@
+{"null": 3.981617965166241}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10796.json
new file mode 100644
index 00000000000..243d3ba1c53
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10796.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.5297479220707615, "GARDASIL": 2.025440118718391, "SPIKEVAX": 1.697504599761782, "VAXZEVRIA": 1.3034120968217269, "null": 0.2700229681847947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10797.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10797.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10798.json
new file mode 100644
index 00000000000..2caf1025c83
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10798.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.5151914317572575, "ALISKIREN": 41.62942490620197, "APIDRA": 1.3392504328170791, "ARAVA": 0.1123795726888458, "ARIPIPRAZOLE": 0.9221660550197752, "AUBAGIO": 3.476620520866339, "BOSULIF": 3.422057776888627, "BUPIVACAINE": 7.997194100663448, "BUSULFAN": 1.308459959882562, "CELLCEPT": 0.7548431311721854, "CHAMPIX": 1.4068854403193565, "CICLOSPORIN": 0.5767801525388692, "CLOPIDOGREL": 1.1412075302285971, "COAPROVEL": 3.470451221009223, "COMIRNATY": 1.0177117833124696, "COSENTYX": 1.6858569853872596, "CYMBALTA": 0.4935635691795185, "ENBREL": 0.7982067969719098, "ENOXAPARIN": 2.4503240959509256, "EXFORGE": 1.1848904221298084, "FASLODEX": 0.903891647923283, "FENTANYL": 2.9392693910962566, "GARDASIL": 3.359104150906897, "HUMALOG": 0.861338589541113, "KEPPRA": 1.101188278561978, "LANTUS": 1.4180230120206867, "LYRICA": 2.750418624739144, "MICARDIS": 1.5080904583122343, "MIDAZOLAM": 1.7722240172773938, "MODERNA": 0.715316231650711, "PEGASYS": 0.4914387912873051, "ROACTEMRA": 1.0026959589168587, "SHINGRIX": 1.504732515316911, "SIMPONI": 0.7155633079862251, "SPIKEVAX": 0.9733226668734573, "STELARA": 0.9420576659266094, "SUTENT": 0.4526364073387242, "TASIGNA": 2.206295927552624, "TOZINAMERAN": 2.141296032699535, "TWINRIX": 2.6068147951063496, "VAXZEVRIA": 1.2786072592528457, "VIAGRA": 1.022149459979716, "XELJANZ": 0.5362465087947558, "XOLAIR": 0.8649549864174172, "ZOSTAVAX": 1.3730317263751752, "ZYPREXA": 0.66564991518304, "null": 0.866884875933303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10799.json
new file mode 100644
index 00000000000..191a5bd10b3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10799.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.709964778643328, "SPIKEVAX": 1.4854651078064611, "VAXZEVRIA": 0.950179542850804, "null": 0.2689035764109245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/108.json
index 5594d90a5b6..be6c27774b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/108.json
@@ -1 +1 @@
-{"null": 6.297862414159445}
\ No newline at end of file
+{"CYMBALTA": 3.2454830037183373, "FENTANYL": 6.420465065478012, "LACOSAMIDE": 29.165359052692548, "OLANZAPINE": 80.61057266553954, "PREGABALIN": 18.4778501981995, "null": 1.6867575795080707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1080.json
index 0db7431a111..b86ef2cca2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1080.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1080.json
@@ -1 +1 @@
-{"EXJADE": 119.8258186310886, "OZEMPIC": 177.15388007970424, "PEGASYS": 3.686231978703912, "SOLIRIS": 10.427783985467917}
\ No newline at end of file
+{"null": 1.7776521739479154}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10800.json
new file mode 100644
index 00000000000..98c575a8297
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10800.json
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10801.json
new file mode 100644
index 00000000000..3f6342260db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10801.json
@@ -0,0 +1 @@
+{"null": 3.790928319436961}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10802.json
new file mode 100644
index 00000000000..4cf3aff6d68
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10802.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10803.json
new file mode 100644
index 00000000000..822e1eb8149
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10803.json
@@ -0,0 +1 @@
+{"ABILIFY": 18.336984555910984, "null": 1.92210181452654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10804.json
new file mode 100644
index 00000000000..4f0f7afd94e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10804.json
@@ -0,0 +1 @@
+{"null": 0.9262403751575256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10805.json
new file mode 100644
index 00000000000..ba627af9b36
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10805.json
@@ -0,0 +1 @@
+{"null": 1.1301177316765705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10806.json
new file mode 100644
index 00000000000..3ead3d8b7b1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10806.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 6.392921300598834, "CICLOSPORIN": 7.185047201718764, "CUBICIN": 36.14716161049614, "null": 1.349258843676656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10807.json
new file mode 100644
index 00000000000..e0b7b72a73b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10807.json
@@ -0,0 +1 @@
+{"null": 0.4335501018639234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10808.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10808.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10809.json
new file mode 100644
index 00000000000..cd4d0a80bc4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10809.json
@@ -0,0 +1 @@
+{"APIXABAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1081.json
index 5911b8d0188..77ea657b7bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1081.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1081.json
@@ -1 +1 @@
-{"HUMALOG": 27.731487781647367, "JARDIANCE": 50.45762181837932, "LANTUS": 15.973630925859489, "LEVEMIR": 49.52114955389936, "NOVORAPID": 102.03766450034472}
\ No newline at end of file
+{"AVASTIN": 31.809550802982965, "TEMOZOLOMIDE": 134.65670303122215, "null": 1.0806001364644553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10810.json
new file mode 100644
index 00000000000..abd7de0ea17
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10810.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.2614245128016682, "ACTRAPID": 1.6536937647599448, "ADALIMUMAB": 0.4026783485687146, "AFINITOR": 0.4883860336724913, "ALEMTUZUMAB": 3.5752921034614227, "ALIMTA": 6.783709797899157, "AMIKACIN": 8.943578777579065, "AMINOSALICYLIC": 0.584544018985804, "ANAKINRA": 3.457157713267575, "ANIDULAFUNGIN": 22.45631767990235, "APIXABAN": 0.1990888958457717, "APREMILAST": 2.0968844127904083, "ARANESP": 0.2756619999517132, "ARAVA": 0.1749277382754961, "ARIXTRA": 6.398672618912167, "ASPARAGINASE": 9.60473461836865, "ATRIPLA": 0.0614587236408679, "AUBAGIO": 0.2811841799724066, "AVANDIA": 0.763553727961075, "AVASTIN": 2.010921705790464, "AXICABTAGENE": 8.30347078718364, "AZACITIDINE": 9.87379374040063, "AZATHIOPRINE": 2.544097823695441, "AZTREONAM": 10.637145308357953, "BASILIXIMAB": 4.759676563143698, "BENLYSTA": 0.8544329400100084, "BENRALIZUMAB": 5.4629795260683, "BEVACIZUMAB": 2.505071086322916, "BORTEZOMIB": 4.768354365269039, "BUDESONIDE": 0.5739235852682394, "BUPRENORPHINE": 0.3552706504861879, "BUSILVEX": 21.38006151640097, "BUSULFAN": 7.994696763568672, "BYETTA": 1.2366713481109337, "CABOMETYX": 0.5425542260771439, "CAELYX": 1.1776919933181436, "CANCIDAS": 13.71752807117186, "CAPECITABINE": 1.3075413232903792, "CARFILZOMIB": 2.012187393393294, "CARMUSTINE": 5.833560595534096, "CASPOFUNGIN": 22.75027581385154, "CELECOXIB": 2.082406160609268, "CELLCEPT": 4.4630454740893, "CICLOSPORIN": 4.020509189763755, "CIMZIA": 0.3343284264039358, "CLADRIBINE": 3.034908918079554, "CLOFARABINE": 12.769989342297688, "CLOPIDOGREL": 0.6738828119125372, "COAPROVEL": 2.511800042232108, "COMIRNATY": 0.0857925957770994, "COSENTYX": 0.5286463365421348, "COTELLIC": 1.7883587731609636, "CUBICIN": 6.954123828398459, "CYMBALTA": 0.1251330892781231, "CYTARABINE": 12.912999659606957, "DAKLINZA": 3.760529087791993, "DAPTOMYCIN": 13.23352250154996, "DARZALEX": 3.717005618366607, "DEFITELIO": 17.19408229592849, "DEXAMETHASONE": 5.603984655104132, "DEXMEDETOMIDINE": 5.164063319775541, "DOCETAXEL": 3.8393598819895898, "DOXORUBICIN": 4.488768541598368, "EFIENT": 2.6366679555462884, "ELIQUIS": 0.7409106519828722, "EMEND": 4.097623196031904, "EMPAGLIFLOZIN": 2.0493199679513547, "ENBREL": 0.6303519461270374, "ENTRESTO": 0.4847072093050203, "ENTYVIO": 0.4525292442368666, "ERBITUX": 2.504274770731291, "EXJADE": 2.3982310973700933, "FASENRA": 0.4891660947996834, "FENTANYL": 0.5034244725348012, "FIDAXOMICIN": 15.916624274892069, "FILGRASTIM": 2.58453074251702, "FIRDAPSE": 1.8133987052951437, "FORSTEO": 0.3335190313786953, "FORXIGA": 1.5726513103309128, "GANCICLOVIR": 7.811146700237906, "GAZYVARO": 3.751810518334477, "HALAVEN": 3.290143991492804, "HARVONI": 2.443701889236736, "HERCEPTIN": 0.9122252838019131, "HUMALOG": 0.1443911773454931, "HUMAN": 1.7755746560721022, "HYDROCORTISONE": 0.6586852459980891, "IBRANCE": 0.3711239532992776, "IBUPROFEN": 1.0407403007368856, "ICLUSIG": 6.230567785036587, "INCIVO": 4.183588544990558, "INFLIXIMAB": 1.909738811386717, "INSULIN": 0.4086618648963068, "INVOKANA": 8.617050485520519, "IPILIMUMAB": 1.4625585331570916, "IRESSA": 0.9480026189822466, "IRINOTECAN": 1.2900586547215689, "JAKAVI": 3.5950263519213386, "JANUMET": 0.7890913221933287, "JANUVIA": 0.6386695258180891, "JARDIANCE": 2.975311670589461, "JEVTANA": 19.48714477896724, "KALETRA": 1.927583856932176, "KEPPRA": 1.420016314867399, "KEYTRUDA": 2.771219958274058, "KYMRIAH": 3.3417569749010974, "KYPROLIS": 4.046336850114739, "LANTUS": 0.3230339113336666, "LEMTRADA": 0.8926227426157102, "LENVIMA": 1.3872212228249996, "LEVETIRACETAM": 1.0026767565047396, "LEVOFLOXACIN": 3.4046376938451046, "LIXIANA": 1.37709675705951, "LONSURF": 2.000584116995454, "MABTHERA": 6.096958661345178, "MEKINIST": 1.6422402697039382, "MELPHALAN": 7.366596790929221, "METHOTREXATE": 2.513403170359279, "MICARDIS": 0.6501299177170319, "MIDAZOLAM": 1.80513440887407, "MIDOSTAURIN": 10.536515340003334, "MIRCERA": 2.2379664197970053, "MYCOPHENOLATE": 7.377238464992605, "NEULASTA": 2.3741487026266617, "NEXAVAR": 0.5390323346292637, "NOT": 0.8960786116535104, "NOVOSEVEN": 8.011561883013968, "NOXAFIL": 4.28646637287122, "NPLATE": 1.4625585331570916, "NUCALA": 0.3933323462046227, "OBINUTUZUMAB": 4.43836908477213, "OLANZAPINE": 0.8617276272427601, "ONCASPAR": 3.514681479114153, "OPDIVO": 1.7845282225632433, "OPSUMIT": 1.7683744673267638, "PACLITAXEL": 2.573697234036233, "PEGASYS": 1.8166864612706195, "PEGINTERFERON": 1.7549038184231214, "PEGINTRON": 0.9824495159625848, "PEMBROLIZUMAB": 0.9918234166960124, "PEMETREXED": 1.5316117439114725, "PLAVIX": 0.5331833660064084, "POSACONAZOLE": 5.027440280304012, "PRADAXA": 3.2376325429390915, "PRAXBIND": 19.5186778324819, "REMDESIVIR": 15.987080773400058, "REVATIO": 1.2996582629386166, "REVLIMID": 2.861313671092111, "RIBAVIRIN": 1.9818002698523367, "RITUXIMAB": 3.883349921069093, "ROACTEMRA": 6.59624662890932, "ROTATEQ": 0.6478410466585522, "RUXOLITINIB": 4.020458857667626, "SIMPONI": 0.4962549786623744, "SOLIRIS": 6.132060042057063, "SOVALDI": 3.187501681052547, "SPIKEVAX": 0.0991086895351344, "SPRYCEL": 1.0778560547739195, "STELARA": 1.0923983058426314, "STIVARGA": 0.3952158157726912, "SUBOXONE": 0.2348769433737692, "SUTENT": 0.6470485207565876, "SYNAGIS": 0.7667415393264824, "TACROLIMUS": 2.38036609686691, "TAMIFLU": 2.096432832703791, "TASIGNA": 0.4214413338156992, "TAXOTERE": 4.0061911267247465, "TELMISARTAN": 1.5771142022512636, "TEMODAL": 2.19057012296935, "THALIDOMIDE": 2.9667337358143904, "TIGECYCLINE": 8.127386617119294, "TOBRAMYCIN": 6.001593484832365, "TOCILIZUMAB": 5.78830968909358, "TOZINAMERAN": 0.0709953601349815, "TRACLEER": 2.370700903992396, "TRASTUZUMAB": 13.413268875353484, "TRELEGY": 0.4726665937390609, "TREMFYA": 0.6883117278008607, "TRODELVY": 5.297168415788171, "TRUVADA": 0.0549868373183819, "VAXZEVRIA": 0.0443118276114798, "VEKLURY": 3.8082340870621, "VELCADE": 4.820167045058219, "VENCLYXTO": 6.066469106452171, "VENETOCLAX": 4.587452767872904, "VFEND": 1.6194062816558, "VIMPAT": 0.832792652284575, "VORICONAZOLE": 3.4798675389559897, "VOTRIENT": 0.2460870766047131, "VYXEOS": 10.34632368369127, "XARELTO": 1.977227134742268, "XELJANZ": 0.2994155460004001, "XELODA": 3.3915362479540616, "XOLAIR": 0.1827112284268026, "XTANDI": 0.8791487770700263, "YERVOY": 1.1447091355198338, "YESCARTA": 5.950482192849383, "YONDELIS": 5.198717897605632, "ZOSTAVAX": 0.3396390922795467, "ZYPREXA": 0.6722002727910646, "null": 0.9962870193597534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10811.json
new file mode 100644
index 00000000000..30ffbe9a2cd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10811.json
@@ -0,0 +1 @@
+{"null": 3.68831327018173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10812.json
new file mode 100644
index 00000000000..9a5c5e4a0fd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10812.json
@@ -0,0 +1 @@
+{"null": 2.9447705698214093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10813.json
new file mode 100644
index 00000000000..82e33128ca5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10813.json
@@ -0,0 +1 @@
+{"TRUVADA": 31.856959587365715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10814.json
new file mode 100644
index 00000000000..0d14608e989
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10814.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1801571199672504, "null": 0.8976462285116079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10815.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10815.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10816.json
new file mode 100644
index 00000000000..ef35232c5c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10816.json
@@ -0,0 +1 @@
+{"ABATACEPT": 7.113872176615304, "ADALIMUMAB": 2.2875156120594, "AMINOSALICYLIC": 30.847126119186527, "ARAVA": 7.056045226563335, "COMIRNATY": 0.600523762979985, "COSENTYX": 19.939573555619717, "HUMIRA": 15.128219776676838, "JANUVIA": 34.66076063786128, "KEYTRUDA": 3.897537586337428, "LEFLUNOMIDE": 41.2441813039429, "SPIKEVAX": 0.2019008546931796, "TOZINAMERAN": 0.6276923223529559, "VAXZEVRIA": 0.1395508403364921, "null": 0.1789049164011306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10817.json
new file mode 100644
index 00000000000..c485ae80fc6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10817.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.453145447074521, "null": 0.8521914137772485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10818.json
new file mode 100644
index 00000000000..8dbedd45ba2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10818.json
@@ -0,0 +1 @@
+{"ABILIFY": 3.056094891446715, "AIMOVIG": 1.450808781012726, "ARIPIPRAZOLE": 8.618418755584734, "AZILECT": 11.671185138329973, "BRINTELLIX": 14.714037263961462, "BUDESONIDE": 0.3337326812013387, "BUPRENORPHINE": 3.966093547275528, "CANNABIDIOL": 6.00236011520579, "CARBIDOPA": 4.387098851481629, "CELECOXIB": 3.2729065572249314, "CHAMPIX": 0.2779665932461159, "CICLOSPORIN": 0.203912849234158, "COMTAN": 3.4868355968211087, "CYMBALTA": 18.65548674830415, "DEXAMETHASONE": 0.2781112138877569, "DULOXETINE": 31.346803260871205, "ESOMEPRAZOLE": 34.30033247545885, "FENTANYL": 10.937972416506891, "IBUPROFEN": 3.9816202556278215, "LACOSAMIDE": 1.4082403946261923, "LATUDA": 2.6108654168673247, "LEVETIRACETAM": 0.957570660993242, "LEVOFLOXACIN": 0.2908966108079541, "LURASIDONE": 34.98809190421349, "LYRICA": 1.061134775901296, "MELATONIN": 1.9433879263447045, "METHYLTHIONINIUM": 224.85939299049392, "MIDAZOLAM": 2.818800052393589, "NOT": 3.847451254053208, "OLANZAPINE": 8.544814339110005, "PANTOPRAZOLE": 1.059659945500984, "PREGABALIN": 0.999949270044908, "RISPERIDONE": 8.687994599418479, "STALEVO": 2.6394945306584607, "SUBOXONE": 1.1290247709985652, "VALDOXAN": 16.484636612791757, "VORTIOXETINE": 31.178105101448192, "XELJANZ": 0.3174161313694121, "ZYPREXA": 3.1322252258774474, "null": 4.172189592415562}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10819.json
new file mode 100644
index 00000000000..0cf7ab172cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10819.json
@@ -0,0 +1 @@
+{"CAELYX": 699.3842590766859}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1082.json
index 7560941474d..74524db2352 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1082.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1082.json
@@ -1 +1 @@
-{"FORXIGA": 63.91517442758578, "HUMALOG": 16.000397660333935, "JARDIANCE": 109.44354931515493, "LANTUS": 5.025602694154197, "LEVEMIR": 12.435394888071787, "METFORMIN": 45.93996937265378, "NOVORAPID": 89.67966453289556}
\ No newline at end of file
+{"TEMOZOLOMIDE": 857.1310857801292, "null": 0.8108853017107754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10820.json
new file mode 100644
index 00000000000..c713e11e229
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10820.json
@@ -0,0 +1 @@
+{"BINIMETINIB": 313.3136554751918, "BRAFTOVI": 1164.8285590885182, "COTELLIC": 107.21847583932563, "EYLEA": 44.758356534613576, "MEKINIST": 37.017826416601885, "null": 0.2072032524210834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10821.json
new file mode 100644
index 00000000000..b3d141cbd1a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10821.json
@@ -0,0 +1 @@
+{"BRAFTOVI": 1040.8470898482908, "COTELLIC": 409.36206245802754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10822.json
new file mode 100644
index 00000000000..0e347a796d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10822.json
@@ -0,0 +1 @@
+{"null": 9.217845328203992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10823.json
new file mode 100644
index 00000000000..276a45dfd22
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10823.json
@@ -0,0 +1 @@
+{"null": 5.774313617995214}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10824.json
new file mode 100644
index 00000000000..0c93ec416f3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10824.json
@@ -0,0 +1 @@
+{"null": 1.3294877529594418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10825.json
new file mode 100644
index 00000000000..0d95c0280db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10825.json
@@ -0,0 +1 @@
+{"BUSILVEX": 2701.909723011382, "null": 1.159683279053483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10826.json
new file mode 100644
index 00000000000..e80f35170e4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10826.json
@@ -0,0 +1 @@
+{"null": 1.1356202846394847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10827.json
new file mode 100644
index 00000000000..fbe1c84582f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10827.json
@@ -0,0 +1 @@
+{"EXJADE": 172.005066865985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10828.json
new file mode 100644
index 00000000000..6f5ada1c2d4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10828.json
@@ -0,0 +1 @@
+{"ADCIRCA": 30.863988873807475, "ARAVA": 1.554542678343894, "CICLOSPORIN": 2.914060563596436, "COMIRNATY": 0.868438942664921, "CYMBALTA": 1.639437636890151, "EXJADE": 19.863293033834637, "GARDASIL": 3.985084809183125, "SIMPONI": 3.4778267499864217, "SPIKEVAX": 0.187785388160402, "TOZINAMERAN": 1.10614718283274, "VAXZEVRIA": 0.1613421307088613, "XELJANZ": 4.377207766581791, "null": 0.7293903175333402}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10829.json
new file mode 100644
index 00000000000..aa41848c7d0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10829.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 2.98048107312372, "ANAKINRA": 9.638291205108745, "ARANESP": 4.795525077971171, "AZACITIDINE": 13.399058781761836, "CICLOSPORIN": 6.527506365602228, "COMIRNATY": 0.2115445285350219, "CYTARABINE": 3.108025899253904, "DEXAMETHASONE": 1.165938774853569, "ENTRESTO": 1.336392817955802, "EXJADE": 199.9848377044482, "HUMIRA": 1.3734110411361036, "JAKAVI": 6.739270263579338, "KEYTRUDA": 0.9607332364989204, "KYMRIAH": 65.39416401357049, "LEVETIRACETAM": 2.4478264342617595, "MIRCERA": 12.76199881401562, "OLANZAPINE": 0.8230373752967728, "PEGASYS": 3.3735598977719947, "PEGINTERFERON": 4.434013604529469, "PEGINTRON": 2.072456724900973, "SOLIRIS": 9.975134033475992, "SPIKEVAX": 0.0886993099153522, "STELARA": 0.9214828979414992, "TOZINAMERAN": 0.307062537215287, "VAXZEVRIA": 0.0733657750302776, "YESCARTA": 9.292896250720664, "null": 0.4855632198219284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1083.json
index 7421501ee2f..8dac8d4e3e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1083.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1083.json
@@ -1 +1 @@
-{"FORXIGA": 12.92633837426362, "HUMALOG": 3.643675920057981, "JARDIANCE": 29.154674865718928, "LEVEMIR": 33.404584010333835, "NOVORAPID": 1137.230427559035}
\ No newline at end of file
+{"BEVACIZUMAB": 80.95628758729818, "TEMOZOLOMIDE": 470.633906066964, "null": 0.4549782352129193}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10830.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10830.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10831.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10831.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10832.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10832.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10833.json
new file mode 100644
index 00000000000..9ce07f4f63f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10833.json
@@ -0,0 +1 @@
+{"null": 2.0370311496868565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10834.json
new file mode 100644
index 00000000000..73b01dbc955
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10834.json
@@ -0,0 +1 @@
+{"null": 2.964922824778398}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10835.json
new file mode 100644
index 00000000000..0a2226b24cd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10835.json
@@ -0,0 +1 @@
+{"CELLCEPT": 5.153811846285623, "CICLOSPORIN": 1.3416253045664976, "CIMZIA": 4.068135772721926, "COMIRNATY": 0.082024746066428, "FASENRA": 11.936858786794447, "GARDASIL": 3.4222455352845254, "PLAVIX": 2.7734326556356352, "RIXATHON": 108.53942842560888, "TOZINAMERAN": 0.2684914011874901, "VAXZEVRIA": 0.0840418307681432, "XOLAIR": 25.031819764707457, "null": 2.895133097990062}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10836.json
new file mode 100644
index 00000000000..4e4d3db4df2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10836.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 0.2282331312864757, "XOLAIR": 10.77172523023931, "null": 4.627256406316481}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10837.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10837.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10838.json
new file mode 100644
index 00000000000..f0b0f840527
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10838.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.634206831425512, "VAXZEVRIA": 13.639850381456492, "null": 0.1270333386005931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10839.json
new file mode 100644
index 00000000000..e0884eaabf1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10839.json
@@ -0,0 +1 @@
+{"CRESEMBA": 2531.003005491023, "null": 0.3722926360196361}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1084.json
index 328bdd1c1cb..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1084.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1084.json
@@ -1 +1 @@
-{"null": 1.19468752748061}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10840.json
new file mode 100644
index 00000000000..27137462bd5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10840.json
@@ -0,0 +1 @@
+{"null": 0.5899625428937079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10841.json
new file mode 100644
index 00000000000..c23dfc88d1a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10841.json
@@ -0,0 +1 @@
+{"null": 1.122026655990208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10842.json
new file mode 100644
index 00000000000..035e38537ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10842.json
@@ -0,0 +1 @@
+{"ORKAMBI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10843.json
new file mode 100644
index 00000000000..b4bb1a09223
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10843.json
@@ -0,0 +1 @@
+{"null": 3.308284671544102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10844.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10844.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10845.json
new file mode 100644
index 00000000000..261e6f74a94
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10845.json
@@ -0,0 +1 @@
+{"VIAGRA": 73.16288561020968, "null": 2.326133632465306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10846.json
new file mode 100644
index 00000000000..0425ad7e9e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10846.json
@@ -0,0 +1 @@
+{"null": 1.7542884862173502}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10847.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10847.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10848.json
new file mode 100644
index 00000000000..788ba49f622
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10848.json
@@ -0,0 +1 @@
+{"ABILIFY": 53.17091304442415, "ARIPIPRAZOLE": 10.463862094157554, "ATRIPLA": 0.1229836717804739, "AUBAGIO": 2.3580882276530084, "BRINTELLIX": 23.5655207637592, "CHAMPIX": 0.6944425446568354, "CICLOSPORIN": 0.4347434507049854, "COAPROVEL": 3.473199309169909, "COMIRNATY": 0.0503076919372981, "COSENTYX": 0.8102323964543622, "CYMBALTA": 2.575624184137526, "DULOXETINE": 5.640972679684298, "LEVETIRACETAM": 1.6105730379191718, "OLANZAPINE": 2.7632843203783835, "SPIKEVAX": 0.0471480850975377, "STRIBILD": 0.8760090036126725, "TRUVADA": 0.4626650402149548, "VAXZEVRIA": 0.0381053408576819, "VIAGRA": 2.252570829932949, "VORTIOXETINE": 41.61842060244262, "ZYPREXA": 3.001530121166997, "null": 4.216844424745227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10849.json
new file mode 100644
index 00000000000..e641aff115e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10849.json
@@ -0,0 +1 @@
+{"null": 3.360667638194712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1085.json
index e84bcb9472c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1085.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1085.json
@@ -1 +1 @@
-{"SOLIRIS": 101.34597063900117}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10850.json
new file mode 100644
index 00000000000..a4fc3433a26
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10850.json
@@ -0,0 +1 @@
+{"TIVICAY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10851.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10851.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10852.json
new file mode 100644
index 00000000000..23b2f49842d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10852.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 26.614216191219576, "null": 1.6114945433878298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10853.json
new file mode 100644
index 00000000000..0c904d021b5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10853.json
@@ -0,0 +1 @@
+{"null": 1.0367874321943449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10854.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10854.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10855.json
new file mode 100644
index 00000000000..f7be4ec590f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10855.json
@@ -0,0 +1 @@
+{"null": 2.7373792987157866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10856.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10856.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10857.json
new file mode 100644
index 00000000000..7025ca5f855
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10857.json
@@ -0,0 +1 @@
+{"null": 1.4902151349234876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10858.json
new file mode 100644
index 00000000000..4445760d2ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10858.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.52683201409783, "AERIUS": 1.4958435706316342, "ALIMTA": 1.001752845739491, "AMIKACIN": 4.433847037674333, "APROVEL": 4.864251415765066, "ARAVA": 0.0673957871847387, "ARIPIPRAZOLE": 0.5377380208141121, "ASPARAGINASE": 0.8139759434022094, "AVANDIA": 0.4481717562923007, "AVASTIN": 3.0503238418718728, "AZATHIOPRINE": 3.113915494090917, "AZTREONAM": 11.323559073794, "BEDAQUILINE": 1.7154940350666184, "BORTEZOMIB": 3.456845078529644, "BRIDION": 5.305633272916933, "BUDESONIDE": 0.4441355164022415, "BUPIVACAINE": 1.6028899676110628, "BUSULFAN": 0.9424454989149053, "BYETTA": 0.5001038318931489, "CELLCEPT": 0.4401670357973088, "CICLOSPORIN": 0.8263653732968006, "CLOPIDOGREL": 1.122386813016122, "COMIRNATY": 0.201455305163089, "CUBICIN": 1.4681966270758615, "CYMBALTA": 0.1841256771254125, "CYTARABINE": 2.0512098708896658, "DEXAMETHASONE": 2.446297975352284, "ELIQUIS": 0.7651338301451035, "ENOXAPARIN": 2.361211600935861, "ENTRESTO": 1.0321417372198145, "EPIVIR": 2.4972995614281515, "ESOMEPRAZOLE": 1.2295200617628537, "EUCREAS": 3.8966614155691, "EXJADE": 0.3066389143423356, "FASLODEX": 0.6510412478432568, "FENTANYL": 1.7203271195603849, "FORSTEO": 0.8996582057528333, "FORXIGA": 1.3300135126954211, "GANCICLOVIR": 4.025557232934711, "GARDASIL": 0.7955649260820777, "GLUCAGON": 16.698931492150127, "HERCEPTIN": 1.2720201975519014, "HUMALOG": 0.3683673706589354, "HUMAN": 0.9312094174320644, "HYDROCORTISONE": 1.2312690866445903, "IBUPROFEN": 4.611865754195066, "ICLUSIG": 1.4738767879147052, "INSULIN": 0.3665730165356337, "INTEGRILIN": 6.224400534317862, "IRBESARTAN": 2.259259824064036, "ISENTRESS": 2.220055463372266, "JAKAVI": 1.8151020439505137, "JANUMET": 0.6049205173449641, "JANUVIA": 0.5863455159645748, "JARDIANCE": 0.687957327314836, "JEVTANA": 4.774154670816518, "KEPPRA": 0.6465462790644291, "KEYTRUDA": 0.8697698941802876, "LACOSAMIDE": 1.123387340593603, "LANTUS": 0.3326792589558829, "LEVETIRACETAM": 0.7287114232376921, "LEVOFLOXACIN": 1.45398818785745, "LYRICA": 0.5258079969049908, "MEKINIST": 0.6412708639006474, "METFORMIN": 3.327023834886204, "METHOTREXATE": 0.9352101333381786, "MICARDIS": 2.622901360421774, "MIDAZOLAM": 1.9339130408234704, "MIRCERA": 2.314983719551967, "NEULASTA": 0.6841169986496872, "NEXAVAR": 0.3706331054043222, "NOT": 1.2771450624337377, "NOVOSEVEN": 4.882720249727275, "OLANZAPINE": 0.9601639521681292, "ONCASPAR": 6.7401354049871465, "OPDIVO": 1.4374921465327626, "OPSUMIT": 0.6774489590629182, "PEGASYS": 0.3096558682679471, "PEGINTRON": 0.5767785109163348, "PEMBROLIZUMAB": 0.7193030114104245, "PIOGLITAZONE": 12.637787872803091, "PLAVIX": 1.2612919252535488, "PRADAXA": 4.418301622348394, "PRAXBIND": 9.637777716063638, "PREGABALIN": 1.2297388072601343, "PRIVIGEN": 1.280829453755964, "PROPRANOLOL": 4.218374595369353, "RASILEZ": 1.9543978992745843, "REMDESIVIR": 9.082042988590944, "ROACTEMRA": 0.4295075091719179, "ROTATEQ": 1.415530130019834, "SAMSCA": 7.025387275642692, "SHINGRIX": 0.2866388527610214, "SOLIRIS": 0.9833555785740172, "SPIKEVAX": 0.104272079174637, "SPINRAZA": 1.073600754250843, "SUFENTANIL": 22.7803855869522, "SUTENT": 0.1724165822210185, "SYNAGIS": 1.4332634301950973, "TAMIFLU": 4.262421730175169, "TELMISARTAN": 3.060508605316859, "TOZINAMERAN": 0.4575693194892811, "TRACLEER": 1.0557986064264573, "TRELEGY": 0.4696618086916064, "VAXZEVRIA": 0.0963456559792086, "VFEND": 1.5816219203647568, "VIAGRA": 0.4898012982424873, "XELJANZ": 0.1767147752382269, "XOLAIR": 0.3415320978761862, "ZYPREXA": 0.3089113761085615, "null": 3.458673297285428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10859.json
new file mode 100644
index 00000000000..5a101c7a366
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10859.json
@@ -0,0 +1 @@
+{"ADENURIC": 11.695711414508777, "AFINITOR": 0.6205725382133964, "APIXABAN": 0.7627771929774421, "APREMILAST": 6.352401593648557, "ARIXTRA": 55.90311496897804, "AVASTIN": 2.3488080521691344, "BASILIXIMAB": 6.822520705231788, "BEDAQUILINE": 2.864585034751503, "BRILIQUE": 13.519153581252205, "BUDESONIDE": 2.08767918449413, "BUSULFAN": 3.634591023744837, "CELLCEPT": 1.2511575466885807, "CICLOSPORIN": 0.4951999035022447, "CLOPIDOGREL": 15.433599399971532, "COMIRNATY": 0.0302917684862355, "CYTARABINE": 0.8514881071435146, "DEXAMETHASONE": 1.0032128675721943, "EFIENT": 34.962023022569696, "ELIQUIS": 11.308444500154662, "ENOXAPARIN": 23.622228929756737, "EXJADE": 0.8341377401538451, "IBUPROFEN": 2.2647258410117925, "KEYTRUDA": 0.3199817411537795, "LIXIANA": 10.4689188616605, "MACITENTAN": 19.145111727715264, "NEXAVAR": 1.4957305916215144, "NOVOSEVEN": 48.33520035500083, "PANTOPRAZOLE": 2.5737017982346955, "PLAVIX": 19.30758978182237, "PRADAXA": 27.35712337530486, "PRASUGREL": 35.73287990223736, "PRAXBIND": 42.25465395635633, "SOLIRIS": 1.2169832692284075, "SPIKEVAX": 0.0257417084528827, "STELARA": 0.4815281638037703, "SUFENTANIL": 4.612095962920212, "SUTENT": 0.6224806827637429, "TICAGRELOR": 8.554998460301464, "VOTRIENT": 0.9428443296628318, "XARELTO": 20.1780348326518, "null": 1.814309827848344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1086.json
index 850c3469d2c..f6cc4db0a54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1086.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1086.json
@@ -1 +1 @@
-{"SOLIRIS": 56.00349057592518}
\ No newline at end of file
+{"SPRYCEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10860.json
new file mode 100644
index 00000000000..cf8ff26748b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10860.json
@@ -0,0 +1 @@
+{"ACTRAPHANE": 779.2051217499967, "ACTRAPID": 342.5580365368121, "APIDRA": 20.10457803489036, "HUMALOG": 31.951748661003386, "INSULIN": 11.424592459688617, "INSUMAN": 565.3150908164297, "LANTUS": 20.47479592133686, "LEVEMIR": 11.66906378464623, "NOVORAPID": 11.985240820837026, "null": 1.0338193880428497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10861.json
new file mode 100644
index 00000000000..6576e2fea0a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10861.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2661619558821216, "VAXZEVRIA": 0.1455761780205672, "null": 4.376368492248719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10862.json
new file mode 100644
index 00000000000..bf67e53c9cd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10862.json
@@ -0,0 +1 @@
+{"null": 3.7738708059543176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10863.json
new file mode 100644
index 00000000000..579f3b969b2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10863.json
@@ -0,0 +1 @@
+{"null": 2.04906311183661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10864.json
new file mode 100644
index 00000000000..4de6bdc542e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10864.json
@@ -0,0 +1 @@
+{"THIOTEPA": 605.5471836042957, "null": 1.7205087782987112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10865.json
new file mode 100644
index 00000000000..177f5e1078e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10865.json
@@ -0,0 +1 @@
+{"STELARA": 18.467384026809075, "null": 0.7504214701924545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10866.json
new file mode 100644
index 00000000000..d4376e2f72f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10866.json
@@ -0,0 +1 @@
+{"null": 0.7451187683907529}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10867.json
new file mode 100644
index 00000000000..7942515844b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10867.json
@@ -0,0 +1 @@
+{"ACETYLSALICYLIC": 383.6489020464991, "ANAKINRA": 113.90256328444424, "ARAVA": 4.293025136184615, "ATRIPLA": 5.2632644813176, "CIMZIA": 2.950902143619341, "ENBREL": 12.755749580623633, "JARDIANCE": 2.7579248864056467, "LANTUS": 2.659774373648379, "SIMPONI": 7.874250786514022, "TRUVADA": 3.618436779042909, "XELJANZ": 6.9100104172608745, "ZOSTAVAX": 7.058168910394287, "null": 0.5924873051859844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10868.json
new file mode 100644
index 00000000000..30e302bde3e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10868.json
@@ -0,0 +1 @@
+{"null": 0.5773065971612161}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10869.json
new file mode 100644
index 00000000000..f185839f79a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10869.json
@@ -0,0 +1 @@
+{"null": 0.737530534340126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1087.json
index 2bf368ac43e..e560ceb56d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1087.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1087.json
@@ -1 +1 @@
-{"ACTOS": 2.7912249829889437, "AFINITOR": 3.536346838385686, "ALEMTUZUMAB": 1.169208156909035, "ASPARAGINASE": 2.303101354047261, "ATAZANAVIR": 1.279550343819898, "AZACITIDINE": 1.4861964331334914, "BARACLUDE": 2.491706391072863, "BAVENCIO": 4.978233153990103, "BEVACIZUMAB": 1.4869564229970185, "BOSULIF": 1.688029977473437, "BRAFTOVI": 1.3619360615701486, "BRUKINSA": 15.394581403588946, "BUSULFAN": 3.005814240597992, "CANCIDAS": 10.262490026935035, "CAPECITABINE": 1.4091832419428365, "CARMUSTINE": 8.406682324824763, "CELLCEPT": 1.8643306105596715, "CICLOSPORIN": 4.856177633997981, "COMBIVIR": 4.3035728758008736, "COMTAN": 2.8737626370562177, "COTELLIC": 4.249604998943078, "CRIXIVAN": 2.4873491159608374, "CUBICIN": 1.526626522088414, "CYTARABINE": 8.172529681973671, "DABRAFENIB": 6.416465175399551, "DEXAMETHASONE": 2.8922586845236564, "DOXORUBICIN": 4.7655335060127015, "EPIVIR": 5.323866467033643, "EVEROLIMUS": 3.642831200084728, "EXJADE": 4.1037315986560206, "FASLODEX": 1.1452983621273565, "FILGRASTIM": 2.6534633858601646, "GAZYVARO": 5.683274155706481, "GLIVEC": 6.630800153905613, "HERCEPTIN": 2.124833871112354, "HUMAN": 1.912677759410916, "HYCAMTIN": 7.454170133962839, "IBRUTINIB": 11.660909976688318, "ICLUSIG": 1.1256082335053894, "INTRONA": 2.900355183044035, "IPILIMUMAB": 1.4538868825064322, "JAKAVI": 12.78110612761754, "KAFTRIO": 1.1754713458371242, "KALETRA": 2.698795790010943, "KEYTRUDA": 1.1247615862190787, "KISQALI": 1.422874875371557, "KYMRIAH": 6.22835359434703, "LEFLUNOMIDE": 1.426341715185316, "LEMTRADA": 2.3838021859965823, "LENALIDOMIDE": 8.256050239808985, "LENVIMA": 1.0798321676633589, "LEVOFLOXACIN": 2.100154410227628, "MANNITOL": 10.213913209647584, "MEKINIST": 4.528790580533598, "MELPHALAN": 4.079842593434381, "METHOTREXATE": 1.2656484710796625, "MICARDIS": 1.7113610448074803, "NEULASTA": 1.1961317851686952, "NEXAVAR": 1.80312749457287, "NPLATE": 1.341153490710769, "OLANZAPINE": 1.694330996162467, "OPDIVO": 1.879522624511642, "PEGFILGRASTIM": 18.46529312678713, "PEGINTERFERON": 1.2622244590999838, "PRIVIGEN": 3.3082874692811566, "PROTELOS": 4.881780841508879, "RASBURICASE": 23.64673172684285, "RIBAVIRIN": 1.594657711450452, "RITUXIMAB": 3.138886849400416, "ROACTEMRA": 1.3373156158182793, "RUXOLITINIB": 5.94750162090218, "SOLIRIS": 35.60085408299439, "STIVARGA": 2.5588509426621973, "SUTENT": 1.8792114417208616, "TAMIFLU": 1.481851908235596, "TASIGNA": 1.1094514949644707, "TORISEL": 2.6574965554513503, "VENCLYXTO": 5.487730788230329, "VENETOCLAX": 7.461897343470305, "VFEND": 2.3278358521066296, "VIRAMUNE": 4.683304377800899, "VOTRIENT": 1.9667630988706053, "XALKORI": 1.7743416382209465, "XOFIGO": 2.1035855469421563, "ZIAGEN": 5.124833864366321, "ZYPREXA": 2.387142234485301, "null": 1.9558712420195865}
\ No newline at end of file
+{"null": 0.5033462095138237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10870.json
new file mode 100644
index 00000000000..44f470ad5e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10870.json
@@ -0,0 +1 @@
+{"ATRIPLA": 10.353014491078952, "AVANDIA": 1.4032932368651445, "COMIRNATY": 0.0230863298146656, "ELIQUIS": 1.7927517221970428, "EVISTA": 6.640975097307915, "FORSTEO": 9.222699851601687, "HUMALOG": 5.059729042021213, "IBRANCE": 2.3811836740252867, "INSULIN": 2.4210588011526992, "KALETRA": 3.127161626497489, "LANTUS": 3.4900448677122653, "STELARA": 1.1694713179447964, "STRIBILD": 7.770960339319937, "SUBOXONE": 2.139143321509044, "SUTENT": 0.5310003509191037, "TRUVADA": 9.612681412791336, "XELJANZ": 5.784968097475387, "XTANDI": 3.944255454997076, "null": 0.9195333561129654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10871.json
new file mode 100644
index 00000000000..d9bc7bac15d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10871.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.16200958546239, "SPIKEVAX": 1.9971436802462403, "TOZINAMERAN": 4.44935992418146, "VAXZEVRIA": 3.349168061851437, "null": 0.0320590779375965}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10872.json
new file mode 100644
index 00000000000..40778a23fcc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10872.json
@@ -0,0 +1 @@
+{"ARAVA": 1.1400745207606406, "ATRIPLA": 0.8287230159573957, "BENLYSTA": 6.981500190706231, "CIMZIA": 3.1323499161345327, "HUMIRA": 6.133072125324795, "JARDIANCE": 2.471207525229015, "LANTUS": 4.958014828299831, "SIMPONI": 14.50434041766916, "STELARA": 3.574120966631085, "XELJANZ": 7.962624297968636, "ZOSTAVAX": 11.694654032285635, "null": 1.239927493328928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10873.json
new file mode 100644
index 00000000000..f4182f3252d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10873.json
@@ -0,0 +1 @@
+{"null": 0.7722266379170711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10874.json
new file mode 100644
index 00000000000..8c2b71b1d99
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10874.json
@@ -0,0 +1 @@
+{"null": 1.41833305981117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10875.json
new file mode 100644
index 00000000000..7bffc201330
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10875.json
@@ -0,0 +1 @@
+{"null": 0.7236372791501491}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10876.json
new file mode 100644
index 00000000000..056e5b4282b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10876.json
@@ -0,0 +1 @@
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10877.json
new file mode 100644
index 00000000000..090155f4a28
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10877.json
@@ -0,0 +1 @@
+{"MENVEO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10878.json
new file mode 100644
index 00000000000..09af8efc0eb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10878.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5750300597637334, "CYTARABINE": 9.264159808038096, "KEYTRUDA": 6.63841663321051, "OPDIVO": 10.437767186324118, "TOZINAMERAN": 0.677818573290598, "ZOSTAVAX": 6.9695289134771015, "null": 0.9216509815192208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10879.json
new file mode 100644
index 00000000000..13cc5c9682d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10879.json
@@ -0,0 +1 @@
+{"OXYBUTYNIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1088.json
index 63167041ab8..ff82c4c0b2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1088.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1088.json
@@ -1 +1 @@
-{"JANUMET": 52.03162005849007, "SPIKEVAX": 3.5993153147261423}
\ No newline at end of file
+{"ABACAVIR": 0.3001273588517206, "ABILIFY": 1.295912362080852, "ACLIDINIUM": 17.626057577583772, "AFINITOR": 0.654594715696441, "AMIKACIN": 2.071857426826283, "ARIPIPRAZOLE": 1.8541620781453512, "ASPARAGINASE": 1.2264030167515871, "ATAZANAVIR": 3.9308349223795833, "ATRIPLA": 0.1052515868306329, "AUBAGIO": 1.3684670869985864, "AZILECT": 7.537200585877913, "BENZODIAZEPINES": 19.931863640616825, "BETAFERON": 3.682963182425097, "BRINTELLIX": 0.6340279737987582, "BRIVIACT": 2.857977774886954, "BUDESONIDE": 0.3531621544228637, "BUPIVACAINE": 1.9679809488075817, "BUPRENORPHINE": 0.7402084904138637, "CAPECITABINE": 1.4379457120527328, "CHAMPIX": 0.5455511767480998, "CICLOSPORIN": 1.2207301943387918, "CLOPIDOGREL": 0.3254145061809715, "COMIRNATY": 0.2536475710799966, "CYMBALTA": 0.7380227433768778, "DEXAMETHASONE": 1.0110672784325092, "EBIXA": 5.481837706584559, "ELIQUIS": 0.1460068376535363, "EMTRICITABINE": 2.82274568064511, "FAMPYRA": 2.711747343660872, "FENTANYL": 0.5097057897733336, "FYCOMPA": 14.899451907782906, "GARDASIL": 2.372710911892667, "HALAVEN": 2.2111469409884283, "IBUPROFEN": 0.8659459883467403, "KEPPRA": 5.818569829368833, "KEYTRUDA": 0.2466464349658375, "LACOSAMIDE": 8.123048307583291, "LEMTRADA": 2.8206254294326585, "LEVETIRACETAM": 12.452946068832151, "LYRICA": 3.209151712420696, "MELATONIN": 4.145151782313103, "MICARDIS": 1.3545570151028523, "MMRVAXPRO": 2.0973131117675377, "NIMENRIX": 1.7657413653299951, "NOVORAPID": 1.546228846944088, "OLANZAPINE": 2.755067842654537, "PANTOPRAZOLE": 5.775324858703687, "PEGASYS": 0.3026278824113912, "PEGINTRON": 1.6083635575216657, "PREGABALIN": 1.5225627763280003, "RISPERIDONE": 5.013150284737163, "SHINGRIX": 0.5175045631991794, "SPIKEVAX": 0.1616476081399842, "STELARA": 0.2436188634842254, "SUTENT": 0.2345619445117753, "TOZINAMERAN": 0.2669191973804019, "VAXZEVRIA": 0.2296007890585105, "VFEND": 0.5732369167850826, "VIMPAT": 6.340599246525355, "XOLAIR": 0.3499630157597937, "ZOSTAVAX": 0.9468740165469398, "ZYPADHERA": 22.57490787699817, "ZYPREXA": 2.008740988940944, "null": 2.9259136925973848}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10880.json
new file mode 100644
index 00000000000..ec10aa794f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10880.json
@@ -0,0 +1 @@
+{"ADCIRCA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10881.json
new file mode 100644
index 00000000000..2955c417f4a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10881.json
@@ -0,0 +1 @@
+{"COMIRNATY": 9.409921143607638, "SPIKEVAX": 3.4800383488956026, "VAXZEVRIA": 0.4384229332908703, "null": 0.1741773347838631}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10882.json
new file mode 100644
index 00000000000..7ab278244a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10882.json
@@ -0,0 +1 @@
+{"EXJADE": 60.007410891245776, "null": 0.5447738916505026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10883.json
new file mode 100644
index 00000000000..2138daef3d8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10883.json
@@ -0,0 +1 @@
+{"ADEMPAS": 15.43620096209162, "COMIRNATY": 0.0747112414922853, "EXJADE": 1974.8523594569065, "OXBRYTA": 1255.2332632313437, "VAXZEVRIA": 0.0941777079513536, "null": 0.1328066260929367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10884.json
new file mode 100644
index 00000000000..b430561f7d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10884.json
@@ -0,0 +1 @@
+{"EXJADE": 295.2599808711, "null": 0.234847004375774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10885.json
new file mode 100644
index 00000000000..edfc283b368
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10885.json
@@ -0,0 +1 @@
+{"null": 1.3784829630660642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10886.json
new file mode 100644
index 00000000000..de99001df4a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10886.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9006492484541282, "TOZINAMERAN": 1.6595068922520029, "VAXZEVRIA": 1.9407461228818377, "null": 0.9216271329364384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10887.json
new file mode 100644
index 00000000000..0fefb6dedf9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10887.json
@@ -0,0 +1 @@
+{"PREVENAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10888.json
new file mode 100644
index 00000000000..d4ab869ec70
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10888.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 5.732059855188034}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10889.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10889.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1089.json
index 6ac5d3e5c05..8407e22b77a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1089.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1089.json
@@ -1 +1 @@
-{"null": 1.000143026188907}
\ No newline at end of file
+{"ADALIMUMAB": 0.6907569327016926, "ADCIRCA": 9.607014183201295, "AFINITOR": 4.082524940608525, "ALIMTA": 1.787832108541149, "APIXABAN": 2.7183499123022314, "APREPITANT": 27.950465274634503, "ARAVA": 0.342644096490694, "BEVACIZUMAB": 1.966520557119333, "BORTEZOMIB": 13.363535612506402, "BUDESONIDE": 0.7900700024861539, "BYDUREON": 2.654626116354473, "BYETTA": 8.327254198124502, "CELLCEPT": 0.7903632900293024, "CICLOSPORIN": 1.1585266918245145, "COMIRNATY": 0.0832837294103818, "CYTARABINE": 5.2362575992736815, "DEXAMETHASONE": 5.003803583179847, "ELIQUIS": 0.8107803768443578, "ESOMEPRAZOLE": 8.56760290466052, "EXJADE": 2.6752595943509974, "FENTANYL": 2.038049676812936, "FIRDAPSE": 3.7577919151614183, "GARDASIL": 0.3881124331899466, "IBRANCE": 0.792592562130769, "IBUPROFEN": 5.624286585018202, "INTEGRILIN": 13.599422902071366, "IRESSA": 2.4266284598894226, "JANUMET": 14.22263159992423, "JANUVIA": 11.915110828589231, "KEYTRUDA": 2.7484267593507123, "KYMRIAH": 4.00220821779747, "MEPOLIZUMAB": 2.0424002982766574, "MIDAZOLAM": 4.134878534193873, "NAGLAZYME": 3.986047322358089, "NOT": 3.1221692277212894, "NPLATE": 4.484617580991387, "NUCALA": 7.4834071708121295, "OLANZAPINE": 1.0808993136097649, "OPDIVO": 1.705343701122561, "OPSUMIT": 0.78790335604661, "OPTIMARK": 2.6281904096161006, "PANTOPRAZOLE": 8.737328800614726, "PEGASYS": 0.4824732033218323, "PEMBROLIZUMAB": 2.2283607107322103, "PLAVIX": 0.4253236073482734, "RITUXIMAB": 1.3703783975512112, "SOLIRIS": 1.2765613527282016, "SPIKEVAX": 0.405493910546244, "SPINRAZA": 33.12181758665838, "SPRYCEL": 1.9566535001927157, "SUTENT": 0.7177535149509355, "SYNAGIS": 9.246859874464857, "TAGRISSO": 2.37771660757051, "TAMIFLU": 1.517002302594888, "TASIGNA": 2.114976600854538, "THALIDOMIDE": 5.550066240676565, "TOZINAMERAN": 0.3149017765935047, "TRELEGY": 1.3000645090671443, "UMECLIDINIUM": 17.477853689630866, "VAXZEVRIA": 0.0598134081678293, "VOTRIENT": 1.322655104392059, "XOLAIR": 0.8673013553066435, "ZOMETA": 23.739961690060543, "ZOSTAVAX": 2.318115654937399, "ZYPREXA": 1.197143906773679, "null": 0.9419388627862773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10890.json
new file mode 100644
index 00000000000..345f343827e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10890.json
@@ -0,0 +1 @@
+{"null": 2.588873808515698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10891.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10891.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10892.json
new file mode 100644
index 00000000000..06277336378
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10892.json
@@ -0,0 +1 @@
+{"AVANDAMET": 133.53069705627797, "AVANDIA": 101.08552263729445, "LANTUS": 6.324984957605673, "null": 0.4001504009932011}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10893.json
new file mode 100644
index 00000000000..671f621f38e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10893.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 63.5994119558334, "OPDIVO": 185.3268309983824, "null": 0.1614163431977241}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10894.json
new file mode 100644
index 00000000000..7171908c2bb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10894.json
@@ -0,0 +1 @@
+{"null": 2.8483266244990126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10895.json
new file mode 100644
index 00000000000..15d616b5adf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10895.json
@@ -0,0 +1 @@
+{"KEPPRA": 47.495102878587446, "null": 1.553171070533807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10896.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10896.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10897.json
new file mode 100644
index 00000000000..2ca14c26fb5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10897.json
@@ -0,0 +1 @@
+{"ELIQUIS": 7.740651910482503, "SUTENT": 4.721462187528247, "null": 0.9302594866885618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10898.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10898.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10899.json
new file mode 100644
index 00000000000..cd8fc6791c8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10899.json
@@ -0,0 +1 @@
+{"null": 2.409928877600295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/109.json
index 67a0e0bbf39..74cb480a341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/109.json
@@ -1 +1 @@
-{"COSENTYX": 12.097881620985778, "KALETRA": 29.81291877964241}
\ No newline at end of file
+{"null": 8.248223136689962}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1090.json
index 28b9df4cbcb..b4ff0d48e6c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1090.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1090.json
@@ -1 +1 @@
-{"null": 2.1497644818720323}
\ No newline at end of file
+{"null": 3.8035161185409874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10900.json
new file mode 100644
index 00000000000..39904cda6a5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10900.json
@@ -0,0 +1 @@
+{"BRILIQUE": 63.446442521043714, "null": 3.3186710091834617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10901.json
new file mode 100644
index 00000000000..289b1ceca00
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10901.json
@@ -0,0 +1 @@
+{"null": 1.068453339061557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10902.json
new file mode 100644
index 00000000000..6fb0712380a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10902.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 9.285437597161811, "COMIRNATY": 0.6557917105723917, "COSENTYX": 11.378701783577911, "NUCALA": 34.27280128008389, "SPIKEVAX": 0.4748870881286548, "TOZINAMERAN": 1.3015251016416047, "VAXZEVRIA": 1.2879516316281137, "null": 0.3906961163334589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10903.json
new file mode 100644
index 00000000000..16a461df71f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10903.json
@@ -0,0 +1 @@
+{"BRIDION": 12.182242646250144, "BRILIQUE": 35.86348459300934, "COMIRNATY": 0.0643963843741848, "FENTANYL": 3.2128528375560768, "IRBESARTAN": 9.985936513252224, "IVABRADINE": 169.8045097608625, "LEVETIRACETAM": 3.0138993808810834, "SPIKEVAX": 0.0882305707854018, "TICAGRELOR": 44.90060240060416, "VFEND": 3.929971468899817, "VIMPAT": 11.929946652569347, "null": 3.6632312770318576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10904.json
new file mode 100644
index 00000000000..4c01c658598
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10904.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9610509007227848, "GARDASIL": 4.011747036133462, "SPIKEVAX": 0.583307996412947, "TOZINAMERAN": 1.059569029735116, "null": 1.596073321198991}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10905.json
new file mode 100644
index 00000000000..b9be55b1a71
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10905.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 2.2245398698973062, "ARIPIPRAZOLE": 2.422321200371797, "ATAZANAVIR": 2.1889202451268, "AVANDIA": 1.0572043755742568, "BEDAQUILINE": 2.07513595212826, "BRILIQUE": 7.43333852702189, "BUDESONIDE": 0.4079919367170549, "CANCIDAS": 3.865508742399375, "CLOPIDOGREL": 0.3422062311042631, "COMIRNATY": 0.1133586276750169, "EBIXA": 14.31911589364448, "ELIQUIS": 0.7026117809928167, "ENTRESTO": 3.0761555731222883, "FENTANYL": 2.5401380958900344, "GARDASIL": 0.3091484296920663, "IBUPROFEN": 2.42529241107542, "IRBESARTAN": 9.246055247944906, "IVABRADINE": 61.21954376347272, "KALETRA": 6.113797233157241, "KEPPRA": 0.9921099084435452, "LACOSAMIDE": 4.872571057607204, "LEMTRADA": 6.043849779524629, "LOPINAVIR": 9.876686050719332, "LYRICA": 0.8516734142993584, "MICARDIS": 1.6130490384676028, "MIDAZOLAM": 1.6739059210683382, "MULTAQ": 4.171222645077596, "OLANZAPINE": 2.123419007987187, "OLYSIO": 7.737885858959147, "PLAVIX": 0.4756058263277167, "PREGABALIN": 6.614531249970632, "PRIALT": 44.4033289509607, "PROPRANOLOL": 7.961699301909221, "RAPISCAN": 29.78775491236836, "REBETOL": 4.087386703594066, "REMDESIVIR": 26.639427019983295, "RIBAVIRIN": 1.5952686330560155, "SIMEPREVIR": 25.700989384498843, "SPIKEVAX": 0.0784588252356728, "SPIRONOLACTONE": 9.197482761365116, "THALIDOMIDE": 4.420869636439437, "TOZINAMERAN": 0.2150329974367821, "VALSARTAN": 4.600619571789881, "VAXZEVRIA": 0.0389234000052346, "VEKLURY": 85.0011454386216, "VIMPAT": 5.197284563639514, "XALKORI": 7.728385090754297, "XARELTO": 2.7091539301764347, "ZYPREXA": 1.520743226008799, "null": 3.6102956845001946}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10906.json
new file mode 100644
index 00000000000..21b9162934f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10906.json
@@ -0,0 +1 @@
+{"AVAMYS": 9.955669215619595, "CHAMPIX": 1.7614717970949514, "CICLOSPORIN": 1.3235375390742223, "CIMZIA": 1.6946294225908274, "COMIRNATY": 0.4132437129913999, "COSENTYX": 5.100734694805777, "ENTYVIO": 2.7531402369466464, "ESBRIET": 3.035460126221565, "GLYCOPYRRONIUM": 68.02362408683393, "HIZENTRA": 3.381141153189217, "HUMALOG": 0.6929029667504971, "HUMIRA": 2.006779628758066, "IBRANCE": 1.9642622269654528, "JANUVIA": 4.322411377141879, "MEPOLIZUMAB": 16.455467576651376, "METHOTREXATE": 2.539760032355505, "NUCALA": 4.596771943402864, "OMALIZUMAB": 6.591192978599831, "OPSUMIT": 6.575476006920368, "PEGINTRON": 1.577663132981244, "SPIKEVAX": 0.8207538173108784, "SUTENT": 0.4352788780837833, "TOZINAMERAN": 2.1981327011364646, "TRELEGY": 2.5125656964924388, "VAXZEVRIA": 0.5543476634938598, "VIAGRA": 2.6223459312784687, "XELJANZ": 3.078780900728268, "XOLAIR": 7.812264648315513, "ZOSTAVAX": 2.2966490131812773, "null": 0.8132324091057918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10907.json
new file mode 100644
index 00000000000..71a096783ed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10907.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 20.17617332845585, "ANORO": 6.186830362960381, "AUBAGIO": 1.734335060909234, "BENLYSTA": 2.621254615195766, "BUDESONIDE": 28.019351824922225, "BYETTA": 1.4881959385000632, "CHAMPIX": 0.7807276648512377, "CIMZIA": 2.3071667970336445, "COMIRNATY": 0.1556056782172605, "COSENTYX": 1.009367343089531, "CYMBALTA": 0.5815204071251742, "ELIQUIS": 0.7059279512229416, "ENBREL": 1.2614698945713014, "ENTYVIO": 1.8969739684599576, "ESBRIET": 2.0918110836836696, "FASENRA": 3.822118817748794, "GARDASIL": 0.5785849265564056, "HIZENTRA": 5.2651886750147465, "HUMIRA": 2.228984268349499, "IBRANCE": 2.835330690625912, "IRON": 13.786226299129686, "LANTUS": 1.0154151341982167, "LYRICA": 2.117225735028589, "MEPOLIZUMAB": 5.42758990316825, "METHOTREXATE": 1.0850596642595844, "NUCALA": 2.558417976471242, "OMALIZUMAB": 5.590695888538009, "OPSUMIT": 2.5053007648137733, "ORKAMBI": 7.228140265439216, "PEGASYS": 1.5790844607894188, "PLAVIX": 1.6164998336403418, "SIMPONI": 0.9287288368777, "SPIKEVAX": 0.153352093536263, "STELARA": 1.0647944893801733, "SUTENT": 1.7610354271886517, "TOVIAZ": 2.8776509727295245, "TOZINAMERAN": 1.322348025036336, "TRELEGY": 3.6599837268637017, "VAXZEVRIA": 0.098427639605891, "VIAGRA": 1.80685381638456, "XELJANZ": 5.122876327078184, "XOLAIR": 4.006661407798301, "XTANDI": 2.6194753839403355, "ZOSTAVAX": 3.938386104867946, "null": 1.1367074941928397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10908.json
new file mode 100644
index 00000000000..9e232fc777a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10908.json
@@ -0,0 +1 @@
+{"ARAVA": 0.4403238294822725, "AVAMYS": 2.7924895014483506, "BYDUREON": 7.075535462899512, "COMIRNATY": 0.67166783808264, "HYDROCORTISONE": 4.154984131077244, "OCRELIZUMAB": 13.080153510882118, "PEGASYS": 0.9231247334694548, "SPIKEVAX": 0.8832061329808619, "STELARA": 1.6404234687297783, "TOZINAMERAN": 5.524699695777712, "VAXZEVRIA": 7.6617231547048705, "XELJANZ": 0.8094158307611592, "XOLAIR": 1.4612895702827515, "null": 0.2111070871328591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10909.json
new file mode 100644
index 00000000000..018201079f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10909.json
@@ -0,0 +1 @@
+{"AVANDAMET": 23.844714122606327, "AVANDIA": 22.91092917009161, "BUDESONIDE": 1.2298911491506097, "BYETTA": 3.329253637347524, "COMIRNATY": 0.1522349021085567, "ELIQUIS": 2.046665351072513, "ENTRESTO": 1.9143357662452496, "EXFORGE": 4.278199541453614, "FENTANYL": 3.795144862718569, "IRBESARTAN": 7.119084460301326, "MICARDIS": 7.238689469577108, "PLAVIX": 1.4354304471724513, "SPIKEVAX": 0.0971637435621221, "VAXZEVRIA": 0.0434759009581267, "VIMPAT": 31.477807612871057, "null": 2.2458036882212142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1091.json
index 3d8741f88c8..41941e55b8f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1091.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1091.json
@@ -1 +1 @@
-{"ABACAVIR": 5.990125632948553, "ARIPIPRAZOLE": 1.3466283369835887, "ATAZANAVIR": 11.725825826076662, "BARACLUDE": 9.249199967021614, "BIKTARVY": 2.7151965260776745, "BUDESONIDE": 30.42592214966272, "COMBIVIR": 15.868558367731406, "CRIXIVAN": 44.87874077578777, "CYTARABINE": 3.445692605092733, "DEXAMETHASONE": 5.075206923498662, "EFAVIRENZ": 5.9203348935162206, "EMPAGLIFLOZIN": 9.599695114040616, "ENFUVIRTIDE": 134.77730553200527, "ENTRESTO": 1.7054109868756293, "EPIVIR": 36.96344941393885, "FENTANYL": 2.053322171063751, "FORXIGA": 1.5659342222614685, "HYDROCORTISONE": 5.0071046681924125, "IBUPROFEN": 2.179345727958625, "INOTUZUMAB": 140.35975034671853, "INVIRASE": 48.75450212338035, "JANUMET": 2.064413452794065, "JANUVIA": 1.5686596496421776, "JARDIANCE": 1.3045973780138147, "KALETRA": 6.3248633928658045, "LAMIVUDINE": 18.976647894607986, "LEVETIRACETAM": 1.39614073361391, "MANNITOL": 36.55478555195216, "METFORMIN": 12.380623713043832, "MIDAZOLAM": 3.992186126185759, "NEVIRAPINE": 13.854278052634928, "NUCALA": 40.259823225568354, "OLANZAPINE": 1.2344909000301003, "OPSUMIT": 1.20296938050638, "SAQUINAVIR": 300.6426071405326, "VIREAD": 3.920168711991569, "ZERIT": 53.96786311775678, "null": 1.411418524461795}
\ No newline at end of file
+{"CLOPIDOGREL": 38.81257897783119, "ELIQUIS": 12.504678555749456, "null": 2.207018844802872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10910.json
new file mode 100644
index 00000000000..1590d0b5709
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10910.json
@@ -0,0 +1 @@
+{"HIZENTRA": 58.7737320079036, "NUCALA": 8.957993134600617, "ORKAMBI": 148.9677654427281, "XOLAIR": 7.436710230346999, "null": 1.096446492935858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10911.json
new file mode 100644
index 00000000000..3ec05c7dbc5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10911.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 15.256119622958796, "BYDUREON": 2.455070637051441, "COMIRNATY": 1.5121555516662823, "ENBREL": 1.3276480923768927, "OCRELIZUMAB": 7.737994939387002, "OMALIZUMAB": 2.16842290078947, "SPIKEVAX": 1.6039819252663028, "STELARA": 1.2586324468281789, "TOZINAMERAN": 3.982457424756957, "VAXZEVRIA": 4.807433838531261, "XELJANZ": 0.6489267842332364, "XOLAIR": 1.1856119010369237, "ZOSTAVAX": 1.9421773100989024, "null": 0.2680997730851671}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10912.json
new file mode 100644
index 00000000000..4f2dc6942b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10912.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 87.31958818224396, "null": 0.7200427593387767}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10913.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10913.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10914.json
new file mode 100644
index 00000000000..f4ed11f6d07
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10914.json
@@ -0,0 +1 @@
+{"APIXABAN": 8.766405632671173, "ARIPIPRAZOLE": 101.97435063046274, "COMIRNATY": 0.4970368387949814, "OLANZAPINE": 5.454095417892417, "SPIKEVAX": 0.3675868066675339, "null": 0.9744161910131972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10915.json
new file mode 100644
index 00000000000..99d886695d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10915.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.8909344169001767, "ACLASTA": 11.970369250518496, "AFINITOR": 0.4964635246324442, "AIMOVIG": 0.4597044814386573, "AMINOSALICYLIC": 1.8336512299377743, "APIXABAN": 0.8199313014176008, "ARAVA": 0.0602063865001425, "ARIPIPRAZOLE": 6.62005948899831, "AVANDIA": 0.9376042141454708, "BEDAQUILINE": 1.848770499039965, "BRIDION": 3.4075240480461804, "BRINTELLIX": 0.5705761597095997, "BUDESONIDE": 0.6053941561815681, "CHAMPIX": 0.3994122114890874, "CLOPIDOGREL": 0.2406362343923119, "COMIRNATY": 0.6897178955923393, "CYMBALTA": 0.7266072667605783, "CYTARABINE": 4.523188940875042, "DARZALEX": 1.6813823396897496, "DELAMANID": 6.6353804990705205, "DEXAMETHASONE": 0.4358111890503361, "DEXMEDETOMIDINE": 10.079415217941746, "DOCETAXEL": 1.3426514255159732, "DULOXETINE": 2.3372676296358885, "ENOXAPARIN": 3.4515770174706604, "ENTRESTO": 0.4994080080745445, "FENTANYL": 1.892710881710223, "FIRDAPSE": 2.104927642603102, "FORSTEO": 0.5506854831046596, "GARDASIL": 0.8099908817832175, "HYDROCORTISONE": 1.1353743556840412, "IBUPROFEN": 2.7089106001893826, "JANUVIA": 0.7132355045861762, "JARDIANCE": 1.1494813090774936, "KEPPRA": 0.3415675439569057, "KEYTRUDA": 0.685024706270692, "KYMRIAH": 1.5566780572450922, "LACOSAMIDE": 3.424921018239825, "LANTUS": 0.1694628510510269, "LEMTRADA": 1.900826964636404, "LEVETIRACETAM": 0.5675485476267288, "LEVOFLOXACIN": 1.2962681457298482, "MELATONIN": 3.3738884825227378, "MEPOLIZUMAB": 0.8965019795023421, "MIDAZOLAM": 6.823320371903463, "NALOXONE": 37.17687997493727, "OLANZAPINE": 5.1921512634924, "PALIPERIDONE": 17.46551794281048, "PEGASYS": 0.2515875002481547, "PRIVIGEN": 1.2337025066443947, "RISPERIDONE": 3.683198345001944, "SPIKEVAX": 0.3614031810983124, "SPINRAZA": 2.5668289144229326, "TOZINAMERAN": 0.7767492196085035, "TRULICITY": 1.3149495337341877, "VAXZEVRIA": 0.2407400774931159, "VIAGRA": 0.8414171365845827, "ZYPADHERA": 4.280952019551647, "ZYPREXA": 3.3499115780926965, "null": 2.2743681664989674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10916.json
new file mode 100644
index 00000000000..f13d303f2fa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10916.json
@@ -0,0 +1 @@
+{"ABATACEPT": 12.634943456683253, "ACLIDINIUM": 2.639619963303937, "ADALIMUMAB": 2.3062526728767696, "ADEMPAS": 1.9324146665437525, "AERIUS": 0.8086206883365301, "AFINITOR": 0.3689703446799003, "AIMOVIG": 0.5718953647502178, "ALEMTUZUMAB": 1.6359583402141815, "ANORO": 2.0924156276719623, "APIDRA": 0.3713710637388528, "ARAVA": 5.587179857308298, "AUBAGIO": 1.4102379763383983, "AVAMYS": 9.97472832818264, "AVASTIN": 0.3171013461133478, "AZACITIDINE": 0.9787691602870168, "AZATHIOPRINE": 0.8291661645224179, "BELIMUMAB": 3.493238138392944, "BENLYSTA": 5.504484730404638, "BIKTARVY": 0.4817248345364608, "BORTEZOMIB": 0.7849229580407796, "BOSULIF": 0.6253475285857213, "BUDESONIDE": 3.041256847833947, "BUSULFAN": 0.4670075967340851, "BYDUREON": 0.7927908980552648, "BYETTA": 0.518987020743153, "CELLCEPT": 0.7701337349845501, "CHAMPIX": 0.4223466691543656, "CHLORHEXIDINE": 40.41583815752922, "CICLOSPORIN": 0.7411649712122957, "CIMZIA": 15.464219053512572, "CINRYZE": 2.282089771147339, "CLOFARABINE": 5.567235863554169, "CLOPIDOGREL": 0.2384729670634892, "COMBIVIR": 2.298957535510994, "COMIRNATY": 0.2915036011986026, "COSENTYX": 2.5460541329934414, "CYMBALTA": 0.9934331457433208, "CYTARABINE": 0.4318126928150978, "DARZALEX": 0.5860878547410643, "DESCOVY": 2.1372414502498835, "DEXAMETHASONE": 0.6066157535043436, "DOXORUBICIN": 0.5737287875138352, "DULOXETINE": 1.081010574224483, "DUPIXENT": 4.080952029629663, "ELIQUIS": 0.4126680939679598, "ENBREL": 1.7423607304812068, "ENTRESTO": 0.5999447079026342, "ENTYVIO": 2.9984230112493626, "ERELZI": 7.115464128585474, "ESBRIET": 1.0984351318183143, "EVENITY": 0.9724214304820326, "EXFORGE": 0.3106569838654164, "EXJADE": 0.7236494297821799, "FASENRA": 2.9444003531689398, "FASLODEX": 0.6262318480278609, "FLUTICASONE": 1.3946820559333233, "FORSTEO": 0.1245152814630784, "GALAFOLD": 2.801534104790178, "GARDASIL": 1.2669795248948863, "HERCEPTIN": 0.4899899463856416, "HIZENTRA": 15.257509065273869, "HUMALOG": 0.4828965216795539, "HUMAN": 1.3562135724700162, "HUMIRA": 2.5063964154649803, "HYDROCORTISONE": 0.6101266733984821, "HYQVIA": 10.134434710573505, "IBRANCE": 1.6652206474142357, "IBUPROFEN": 0.2649077659880007, "IMBRUVICA": 1.630032131669361, "INCRUSE": 1.1138580744845896, "INLYTA": 0.2693821899192635, "INSULIN": 0.2780505968892678, "JAKAVI": 0.2328001248537068, "JANUMET": 0.6452130667147873, "JANUVIA": 0.2485705339260365, "JARDIANCE": 0.260378668433511, "KAFTRIO": 1.5338590174170978, "KALETRA": 0.4469035550134581, "KALYDECO": 6.084885762412976, "KEPPRA": 0.2660117437219846, "KESIMPTA": 1.2972686491342205, "KEYTRUDA": 0.2677427450964093, "LANTUS": 0.5301116530870003, "LEFLUNOMIDE": 3.118823930010845, "LEVEMIR": 0.4679382280562754, "LEVOFLOXACIN": 0.6456133531944083, "LYRICA": 0.496717726571922, "MEKINIST": 0.2470248186749922, "MEPOLIZUMAB": 5.028846166511029, "METHOTREXATE": 2.013860612433495, "MICARDIS": 0.940798553031278, "MMRVAXPRO": 0.1504687185835822, "MYCOPHENOLATE": 0.7532016800858344, "NEULASTA": 0.726665787496333, "NEXAVAR": 0.1019399808178846, "NORVIR": 0.7446959123751633, "NOT": 0.6097271042026964, "NPLATE": 0.5818308106909449, "NUCALA": 5.583323919399732, "OCALIVA": 1.8425093838619937, "OCRELIZUMAB": 0.7566662237521642, "OFEV": 0.7791949086635428, "OMALIZUMAB": 6.780240809652442, "OPSUMIT": 1.6741435672043556, "ORKAMBI": 4.463458862366823, "OZEMPIC": 5.464576569426344, "PANTOPRAZOLE": 0.5788008169681959, "PEGASYS": 1.3485232417412327, "PEGINTERFERON": 0.2733682925341207, "PEGINTRON": 0.8990314957763454, "PLAVIX": 0.187174269193218, "POSACONAZOLE": 2.3034153117200864, "PRIVIGEN": 1.9550545020495933, "RELVAR": 3.329126912064684, "REMICADE": 2.410440625364954, "REVATIO": 0.9449201113681328, "REVLIMID": 1.0451529542913844, "RINVOQ": 1.500406178400356, "RITUXIMAB": 2.6023127258758327, "ROACTEMRA": 1.4526149987159305, "RUCONEST": 6.101029614380689, "RUXOLITINIB": 1.2135348785755045, "SHINGRIX": 0.2756321179181024, "SIMPONI": 3.247646004490337, "SOLIRIS": 1.2247123346904096, "SPIKEVAX": 0.2633915369141009, "SPINRAZA": 0.7351696922739278, "SPRYCEL": 1.104023616025186, "STELARA": 1.618935136322692, "SUBOXONE": 0.1787957230238324, "SUTENT": 0.3945132816502536, "TAMIFLU": 0.6298125574290663, "TASIGNA": 0.2867522323523093, "TOZINAMERAN": 0.6990503600215805, "TRACLEER": 0.96984379987861, "TRELEGY": 1.1084056637335156, "TREMFYA": 0.9876215089769768, "VARENICLINE": 12.125655844010716, "VAXZEVRIA": 0.2532729934556695, "XELJANZ": 5.763707778697701, "XOLAIR": 4.743780779947715, "XTANDI": 0.2880785304438826, "XYREM": 3.5627476951660317, "ZOSTAVAX": 1.8725646049920357, "ZYPREXA": 0.5439311987684502, "null": 0.677893605596462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10917.json
new file mode 100644
index 00000000000..9cdfeedba77
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10917.json
@@ -0,0 +1 @@
+{"HUMIRA": 17.94029116166011, "XELJANZ": 11.754447949245709, "null": 0.9336851703343269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10918.json
new file mode 100644
index 00000000000..4ea5fada63b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10918.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 34.31395774472666, "BUDESONIDE": 43.89791654029119, "CYTARABINE": 21.267871927788896, "IRON": 125.0468043360552, "null": 0.3482247750578215}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10919.json
new file mode 100644
index 00000000000..f033f9fb494
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10919.json
@@ -0,0 +1 @@
+{"ATRIPLA": 6.293500869826232, "COMIRNATY": 1.423206003058607, "SPIKEVAX": 1.446648043265172, "TOZINAMERAN": 2.596678462965661, "TRUVADA": 3.3138221009016453, "VAXZEVRIA": 0.444001326589611, "null": 0.4704871702189835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1092.json
index 93712720ef9..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1092.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1092.json
@@ -1 +1 @@
-{"ARIXTRA": 44.05024982817037, "BRILIQUE": 20.400359056318443, "BYETTA": 4.24326773698921, "CLOPIDOGREL": 42.42772001214277, "EFIENT": 16.77769326125134, "ELIQUIS": 11.635155061163964, "ENOXAPARIN": 6.0924606814262745, "JANUMET": 1.8434176702456992, "JANUVIA": 2.7426803045975863, "LIXIANA": 7.305957493458125, "NEXAVAR": 1.2390250262150293, "PLAVIX": 29.43288107468145, "PRADAXA": 35.61284548976116, "STIVARGA": 1.4135485083701214, "TICAGRELOR": 50.74725054408197, "XARELTO": 39.12333146256927, "null": 1.371628064621414}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10920.json
new file mode 100644
index 00000000000..48e0badb88c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10920.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.3972088068465498, "ARAVA": 4.287293736055015, "AZATHIOPRINE": 4.836051173277497, "BENLYSTA": 5.598950467182258, "CELLCEPT": 1.7791578283368046, "CICLOSPORIN": 0.8077897158380831, "CIMZIA": 2.035564095747854, "COMIRNATY": 0.5804095060093449, "COSENTYX": 4.617475612685652, "CYMBALTA": 0.7240588991791544, "ENBREL": 6.010644337283739, "GARDASIL": 2.0507832578007363, "HUMIRA": 4.661747238142616, "IPILIMUMAB": 11.430293049913464, "KEYTRUDA": 6.088754211896188, "LEFLUNOMIDE": 11.636508659396393, "LYRICA": 2.897113537690764, "MICARDIS": 5.987456186707822, "OPDIVO": 3.701618463095721, "PEGASYS": 2.075421285968232, "PEGINTRON": 2.178699722143336, "PEMBROLIZUMAB": 8.423050300994403, "SIMPONI": 3.9645740979245336, "SPIKEVAX": 0.3224832551311704, "TELMISARTAN": 26.32475250699679, "TOZINAMERAN": 1.1952913629026145, "VAXZEVRIA": 0.141714178990491, "XELJANZ": 5.333067034199377, "ZOSTAVAX": 1.651046111052453, "null": 0.713054078628588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10921.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10921.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10922.json
new file mode 100644
index 00000000000..090770be764
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10922.json
@@ -0,0 +1 @@
+{"null": 2.044969251576027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10923.json
new file mode 100644
index 00000000000..41d742a7a68
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10923.json
@@ -0,0 +1 @@
+{"ATRIPLA": 114.84829914618383, "KALETRA": 8.029665965661613, "STRIBILD": 24.51679949132032, "SUTENT": 0.0295411405765068, "TRUVADA": 44.38344892571856, "VIREAD": 17.918695881925714, "null": 0.0050114135285702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10924.json
new file mode 100644
index 00000000000..e67a41b0802
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10924.json
@@ -0,0 +1 @@
+{"APIXABAN": 1.3294495257356729, "APREMILAST": 4.924091944392407, "BUPRENORPHINE": 2.631155511211812, "CICLOSPORIN": 0.7790378885223629, "COMIRNATY": 0.2664765383582453, "COSENTYX": 1.0660692117687656, "CYMBALTA": 2.192051263992367, "CYTARABINE": 3.16818893193674, "DEXAMETHASONE": 3.369096706702376, "ELIQUIS": 1.770081800921583, "FENTANYL": 4.840864251104226, "GARDASIL": 1.389782197936583, "HUMALOG": 0.965368427159888, "IBRANCE": 1.110474628614276, "IMIQUIMOD": 54.20172693234086, "JARDIANCE": 2.299953343937678, "KEPPRA": 1.6037441819594165, "LANTUS": 0.6491604204528896, "METHOTREXATE": 2.3223254492390524, "NAGLAZYME": 7.639355211964621, "OLANZAPINE": 1.0528163665358286, "OPTIMARK": 6.947744541526506, "PEGASYS": 0.6759781262900949, "PEGINTRON": 1.564470410901586, "SPIKEVAX": 0.3273946489633162, "SUTENT": 2.7391292905527265, "TOZINAMERAN": 0.7170726302275976, "VAXZEVRIA": 0.0939688119326424, "XELJANZ": 1.2205694015380413, "ZOSTAVAX": 2.55931868652413, "ZYPREXA": 1.018401773658875, "null": 1.274108118072982}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10925.json
new file mode 100644
index 00000000000..c81d5940585
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10925.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 1.916575569502721, "CICLOSPORIN": 5.603112162703068, "CLOPIDOGREL": 0.9538176909992068, "COMIRNATY": 0.1018019628681178, "COSENTYX": 2.4683524757308173, "DULOXETINE": 4.653145931582041, "ELIQUIS": 1.4904192925397584, "ENBREL": 1.2489837931036956, "HYDROCORTISONE": 19.17172830135153, "LANTUS": 0.5931969933680923, "MEPOLIZUMAB": 6.595300238857327, "METHOTREXATE": 1.8090171354236324, "NEXAVAR": 1.158975632463709, "NUCALA": 1.6695152936655346, "OMALIZUMAB": 4.502160002420401, "OPTIMARK": 22.917234094784803, "PROTOPIC": 92.85848978278298, "RENVELA": 569.6801783734003, "SUTENT": 6.306586957481456, "VAXZEVRIA": 0.056489356460726, "XELJANZ": 0.9813391229216364, "null": 1.8589722623140503}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10926.json
new file mode 100644
index 00000000000..5cd1178515b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10926.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2298740229890217, "SPIKEVAX": 0.5468106010638221, "null": 0.8575241561004061}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10927.json
new file mode 100644
index 00000000000..92ecc3171ab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10927.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.2434695210678578, "ALDARA": 9.393943348875805, "APIDRA": 0.6723472518575421, "ARANESP": 0.3703227380183387, "AUBAGIO": 0.9375996095487474, "AVAMYS": 0.8096994817006192, "BENLYSTA": 1.081855274561126, "BRINTELLIX": 1.2348917751270467, "CHAMPIX": 0.4542200004894755, "CICLOSPORIN": 0.5402452408738848, "CIMZIA": 0.2098984512208792, "CLOPIDOGREL": 0.232435579313436, "COMIRNATY": 1.416184417908193, "CONTRAST": 10.057376272929451, "COSENTYX": 1.7725990245203895, "CYMBALTA": 0.421436818330486, "ELIQUIS": 0.3672224365136446, "ENTRESTO": 0.3807511688960301, "ENTYVIO": 0.4332162188110601, "ESBRIET": 1.3619500686108088, "FASLODEX": 0.8716601178048152, "FORSTEO": 0.5185471883285524, "FORXIGA": 0.511188802493106, "FULVESTRANT": 0.967304288790368, "GARDASIL": 0.4554868221564389, "HIZENTRA": 0.6745177020263832, "HUMIRA": 0.6946765987595915, "HYDROCORTISONE": 14.342196795249595, "IBRANCE": 0.3473239022793936, "IBUPROFEN": 0.4220425002074709, "INCIVO": 0.775831621598991, "JANUVIA": 0.3183862967378164, "JARDIANCE": 0.3554520584368956, "KEPPRA": 0.3216325150173711, "KEYTRUDA": 0.1421474558647875, "LANTUS": 0.3550863262544717, "LEVOFLOXACIN": 0.5583415102342763, "LYRICA": 1.3103438550504554, "MIRVASO": 105.16860408228771, "NEXAVAR": 0.7244455219944663, "OCRELIZUMAB": 1.3924796990790944, "OMALIZUMAB": 0.6666703882119221, "OPTIMARK": 4.085533061709405, "PEGASYS": 0.7376205403325521, "PLAVIX": 0.2077402896078438, "PROTOPIC": 26.842292689015668, "QUTENZA": 6.237275929931049, "RIBAVIRIN": 0.7720423533651014, "RINVOQ": 1.5425772393068138, "RITUXIMAB": 0.416936704507901, "SHINGRIX": 1.7469124442482595, "SIMPONI": 0.4168801771584882, "SPIKEVAX": 1.2054739351497126, "STELARA": 0.7641748972882528, "STIVARGA": 0.4191095347521502, "SUBOXONE": 0.429598124199608, "SUTENT": 0.7812055128554816, "TOZINAMERAN": 1.4376887429838314, "VAXZEVRIA": 1.2991839086655332, "VIAGRA": 0.579072602596682, "XELJANZ": 0.4023650297802554, "XOLAIR": 1.3932854872217104, "ZOSTAVAX": 0.6553658676529663, "ZYCLARA": 9.35178344231789, "null": 1.3615796655914465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10928.json
new file mode 100644
index 00000000000..1ca3221b5ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10928.json
@@ -0,0 +1 @@
+{"AIMOVIG": 2.3603978298180914, "AUBAGIO": 1.0960268435186966, "BENLYSTA": 1.656518440237497, "BYDUREON": 1.0499756510954217, "BYETTA": 1.1276191658785502, "CELLCEPT": 8.482130068151777, "CICLOSPORIN": 3.3953975250735358, "CIMZIA": 2.6500951334330227, "COMIRNATY": 0.0278362949703717, "COSENTYX": 1.338642917920153, "ELIQUIS": 2.2367216557830725, "ENTYVIO": 1.749552278907708, "ESBRIET": 2.9560538632412907, "EXFORGE": 2.187589551048494, "FORSTEO": 0.6435693196903478, "HUMALOG": 1.0314449534307153, "HUMIRA": 3.05704990077892, "IBRANCE": 0.800036597476993, "JAKAVI": 12.998871154198088, "JANUMET": 1.430352540706577, "JARDIANCE": 0.8638369320098731, "KEPPRA": 0.5058508875234922, "LANTUS": 1.9197694977375432, "MEKINIST": 2.329583616851272, "METHOTREXATE": 1.3246079583819457, "PEGINTRON": 0.4890724869036393, "PLAVIX": 0.4861825860277723, "RAPAMUNE": 26.022778122438574, "REVLIMID": 7.360029362946898, "RINVOQ": 3.834460634460203, "ROACTEMRA": 1.520748271780104, "SIMPONI": 4.78025856512243, "SOLIRIS": 1.1630091771420918, "SPRYCEL": 1.7826030262341772, "STELARA": 4.6242287730388005, "SUTENT": 0.3949030570578665, "TREMFYA": 4.763436490286808, "VAXZEVRIA": 0.018274850771968, "VFEND": 7.806541663947764, "VIAGRA": 3.5691967828631066, "XELJANZ": 12.0864299518885, "XOLAIR": 1.198626761031163, "XTANDI": 0.9276823605423024, "ZELBORAF": 5.579448324591023, "ZOSTAVAX": 5.461340786166372, "null": 1.9376831428379149}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10929.json
new file mode 100644
index 00000000000..e0eef1077ec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10929.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1093.json
index bb6d39dc1ab..3982c4303f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1093.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1093.json
@@ -1 +1 @@
-{"null": 3.3811543937641435}
\ No newline at end of file
+{"null": 0.6842411932383017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10930.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10930.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10931.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10931.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10932.json
new file mode 100644
index 00000000000..446c817514a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10932.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10933.json
new file mode 100644
index 00000000000..48f1427fbfc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10933.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10934.json
new file mode 100644
index 00000000000..dc4d1b97530
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10934.json
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10935.json
new file mode 100644
index 00000000000..f72fce156c1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10935.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10936.json
new file mode 100644
index 00000000000..3aba7b10103
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10936.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10937.json
new file mode 100644
index 00000000000..63a53d90524
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10937.json
@@ -0,0 +1 @@
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diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10938.json
new file mode 100644
index 00000000000..43d37336d3d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10938.json
@@ -0,0 +1 @@
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diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10939.json
new file mode 100644
index 00000000000..b621ada483b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10939.json
@@ -0,0 +1 @@
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0.1241015599513757, "LEVETIRACETAM": 0.956494947432056, "LEVOFLOXACIN": 1.7709299044491154, "LIXIANA": 0.854539734008287, "LONSURF": 1.349132564689234, "LYRICA": 0.4385605070994631, "MEKINIST": 0.9396842668400324, "METFORMIN": 9.748322001508733, "METHOTREXATE": 1.200548910658592, "MICARDIS": 0.593139765262251, "MMRVAXPRO": 0.4096342209459374, "MODERNA": 0.2004661627778397, "MULTAQ": 0.6786074022707518, "MYCOPHENOLATE": 1.3702573812407393, "NEULASTA": 0.5670590678457504, "NEVIRAPINE": 13.705335866268175, "NEXAVAR": 6.737145521819704, "NINLARO": 1.7256066909442065, "NUCALA": 0.2251625869888925, "OFEV": 0.3930839472197725, "OLANZAPINE": 0.2183151555120724, "OLYSIO": 2.2929879370282253, "OMALIZUMAB": 0.6910748601468787, "OPDIVO": 0.6270984300628212, "OPSUMIT": 0.164464443246087, "OPTIMARK": 7.965240173412081, "PANTOPRAZOLE": 0.8283943944375274, "PEGASYS": 1.285144557239798, "PEGINTERFERON": 1.6515842351539345, "PEGINTRON": 0.8087532424904774, "PEMBROLIZUMAB": 0.6988522209648371, "PEMETREXED": 1.9569380862836037, "PLAVIX": 0.9227542921584988, "PRIVIGEN": 3.0250790818081814, "PROTOPIC": 12.02104929625176, "RAPAMUNE": 1.4168658914687653, "RELVAR": 0.9754548147629962, "RENVELA": 60.35200244047112, "REVLIMID": 1.4154026799140282, "RINVOQ": 1.349106327910501, "RITUXIMAB": 0.2556315147545324, "ROACTEMRA": 1.0109984440813822, "SHINGRIX": 0.7622041468807054, "SIMPONI": 1.214880474249308, "SKYRIZI": 4.713151523368958, "SORAFENIB": 2.8192660283382813, "SOVALDI": 1.057941708576869, "SPIKEVAX": 0.2271202080862912, "SPRYCEL": 1.0353089532505442, "STELARA": 1.855505581342264, "STIVARGA": 9.657830387498988, "SUTENT": 6.499159210154603, "TAGRISSO": 1.709919446540009, "TAMIFLU": 2.3195155944269445, "TASIGNA": 0.985705018759562, "TAXOTERE": 4.51448753622689, "THALIDOMIDE": 1.6256496575029098, "TOZINAMERAN": 0.5229770892102009, "TRELEGY": 0.3479675247246717, "TREMFYA": 2.7409393965666795, "TRULICITY": 0.3575225487977684, "VAXZEVRIA": 0.2172171764716483, "VECTIBIX": 2.359484520363897, "VFEND": 2.395845571748475, "VORICONAZOLE": 0.6802390935373261, "VOTRIENT": 1.3985718853851796, "XARELTO": 0.7254650677757483, "XELJANZ": 0.4241887223454257, "XELODA": 1.4544355159623317, "XOLAIR": 0.8530458920961902, "XTANDI": 0.5802760879394022, "ZELBORAF": 4.663787839091613, "ZOSTAVAX": 0.3313795235516218, "null": 1.6712016670093386}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1094.json
index a09d251b5e9..f5cdd8cf629 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1094.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1094.json
@@ -1 +1 @@
-{"BUSULFAN": 295.7777902260594, "DOXORUBICIN": 382.81432429938366}
\ No newline at end of file
+{"null": 2.898277100902257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10940.json
new file mode 100644
index 00000000000..157ebd32b10
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10940.json
@@ -0,0 +1 @@
+{"CONTRAST": 175.33973903413334, "OPTIMARK": 1003.5737319449272, "null": 0.9281256636863712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10941.json
new file mode 100644
index 00000000000..5ac87e7df4c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10941.json
@@ -0,0 +1 @@
+{"ANAKINRA": 8.313411555064963, "BRAFTOVI": 4.60250612929561, "CABOMETYX": 2.5775962657538427, "CAPECITABINE": 7.490617293795264, "CETUXIMAB": 25.5101441558486, "COMIRNATY": 0.1889690468021696, "CONTRAST": 40.31965496019155, "COSENTYX": 5.6805401495915575, "ELIQUIS": 0.6098425738891852, "ENTRESTO": 1.6768358248368218, "ERBITUX": 28.77203524874415, "FORXIGA": 2.0475625783410822, "HERCEPTIN": 3.87366899550238, "HYDROCORTISONE": 4.395365946408305, "IBRANCE": 1.480791932853071, "IRESSA": 8.94937851549259, "JARDIANCE": 5.789555819032776, "NEXAVAR": 11.052755173513928, "OPTIMARK": 10.138605314112649, "PEGASYS": 3.6001088599828157, "RIBAVIRIN": 3.4608382545625664, "SIMPONI": 2.0447694318975693, "SPIKEVAX": 0.1715932303435668, "STELARA": 1.2345370558944404, "STIVARGA": 14.26684554132523, "SUTENT": 15.581945224212548, "TAGRISSO": 16.32960554174431, "TOZINAMERAN": 0.2668432551701669, "VAXZEVRIA": 0.1054906107540815, "VECTIBIX": 47.82367735227727, "VOTRIENT": 1.677964507326964, "XELJANZ": 0.6095328983810295, "null": 0.7739255272724823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10942.json
new file mode 100644
index 00000000000..e6a9c41d6b3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10942.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 240.926742827478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10943.json
new file mode 100644
index 00000000000..fda49feb783
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10943.json
@@ -0,0 +1 @@
+{"MEPOLIZUMAB": 52.95749480413028, "NUCALA": 16.470920461925434, "OMALIZUMAB": 20.832489441107818, "null": 0.9588897423735562}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10944.json
new file mode 100644
index 00000000000..95d548315c7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10944.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 17.949211266950037, "null": 0.9768327477008965}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10945.json
new file mode 100644
index 00000000000..5a3673d06a3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10945.json
@@ -0,0 +1 @@
+{"NEXOBRID": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10946.json
new file mode 100644
index 00000000000..27de808e73e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10946.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.2776555722854344, "ALISKIREN": 11.37354959952812, "ARAVA": 0.1263435852694888, "AUBAGIO": 1.1519704989447688, "BENLYSTA": 1.373804579861132, "BRILIQUE": 6.420368802818183, "CICLOSPORIN": 1.434375294776964, "CLOPIDOGREL": 3.934729819969421, "COMIRNATY": 0.7978213626077787, "COSENTYX": 3.831800915996351, "CYMBALTA": 0.7330866013159913, "ELIQUIS": 6.650000380848165, "ENBREL": 1.590263735252026, "ENOXAPARIN": 3.414989228674249, "HUMALOG": 0.769014422244472, "HYDROCORTISONE": 2.697941298279648, "IBRANCE": 0.9961329894428904, "JAKAVI": 2.960152434415458, "LANTUS": 0.8954714282568795, "LIXIANA": 25.5875690470194, "MMRVAXPRO": 0.9057769893095096, "NEXAVAR": 1.1196484484259244, "NPLATE": 5.2726423749860265, "OCALIVA": 12.10929645087012, "OMALIZUMAB": 2.0342610067564024, "PEGASYS": 0.489994126249575, "PLAVIX": 5.329236524861156, "RENVELA": 300.7692327937437, "SIMPONI": 0.6465479374814765, "SPIKEVAX": 0.4134701414495712, "SUTENT": 3.2615613082870403, "TOZINAMERAN": 0.3837751469822233, "TREMFYA": 3.192228383502598, "VAXZEVRIA": 1.2615899640773611, "XARELTO": 8.549732001107788, "XELJANZ": 0.5192000601080782, "ZOSTAVAX": 0.5795411738952622, "null": 0.8182929982676012}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10947.json
new file mode 100644
index 00000000000..b9942911f1c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10947.json
@@ -0,0 +1 @@
+{"ALIMTA": 6.506928888966977, "BEVACIZUMAB": 2.798264761842213, "BRAFTOVI": 5.37626273244945, "BUSULFAN": 2.7976045944644503, "CAELYX": 9.01758605148926, "CICLOSPORIN": 4.054276546222424, "COMIRNATY": 0.1050450698250094, "CONTRAST": 82.6334529674112, "COSENTYX": 2.1333108195549166, "EMEND": 12.205053323347792, "HYDROCORTISONE": 10.445511434852934, "LEVOFLOXACIN": 3.1358123947609737, "OPTIMARK": 98.62015591298464, "PEGASYS": 0.6938889134841688, "PEGINTERFERON": 2.8590961768122565, "PEMETREXED": 7.596153956270079, "SPIKEVAX": 0.0535014202411056, "SUTENT": 0.3585362394815324, "VAXZEVRIA": 0.0643285599327511, "ZOSTAVAX": 1.0071480123616643, "null": 1.7505266701189903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10948.json
new file mode 100644
index 00000000000..f79d8271785
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10948.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 1.028299873529421, "CIMZIA": 0.907660895920426, "COMIRNATY": 0.1683764707053003, "CONTRAST": 237.54789074649744, "COSENTYX": 2.361741986647455, "NEXAVAR": 3.13637128543387, "OPTIMARK": 432.90689983110553, "SPIKEVAX": 0.1259761770791073, "SUTENT": 3.940237016269292, "VAXZEVRIA": 0.0458011713471312, "null": 0.8666180319836153}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10949.json
new file mode 100644
index 00000000000..80abd967e29
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10949.json
@@ -0,0 +1 @@
+{"OPTIMARK": 38.29635548342187, "null": 1.0800052087644854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1095.json
index 6d0b4f9cb09..4458d5b7872 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1095.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1095.json
@@ -1 +1 @@
-{"AFINITOR": 2.228789683783329, "ALIMTA": 3.086813710840838, "AMINOSALICYLIC": 18.28801422372262, "BEDAQUILINE": 45.58691371230553, "BENZODIAZEPINES": 78.41658415073468, "CABOMETYX": 4.089025199040412, "CAPECITABINE": 8.340903484805855, "CICLOSPORIN": 1.5500367369231762, "DOXORUBICIN": 7.547550354952121, "EMEND": 14.809533992840915, "EVEROLIMUS": 13.762875400735172, "FENTANYL": 2.522379773436788, "FILGRASTIM": 14.911725946718452, "FIRDAPSE": 9.202451250214928, "HERCEPTIN": 4.846376007144799, "HUMALOG": 1.566757046166971, "IBRANCE": 1.9634365994809453, "INLYTA": 2.6643968558096285, "JANUMET": 3.2423120843359223, "KEYTRUDA": 1.4229286340151432, "LEVOFLOXACIN": 1.573323324008595, "MIDAZOLAM": 10.386767069033883, "OPSUMIT": 3.040778531316962, "PANTOPRAZOLE": 15.218748543545493, "PEGINTRON": 1.5767766998046715, "PLAVIX": 1.0417183326820183, "RUBRACA": 33.12169306081485, "SOLIRIS": 1.7578313804700227, "SUTENT": 3.281181068070249, "TACROLIMUS": 14.473511721623495, "VECTIBIX": 23.500793987521423, "VELTASSA": 11.610696779373075, "VFEND": 2.2536547217379588, "VOTRIENT": 1.6561827793239183, "ZOSTAVAX": 1.078929667846004}
\ No newline at end of file
+{"BRIVIACT": 65.32405116475624, "COMIRNATY": 0.3629703832152515, "GARDASIL": 3.1818444584995884, "KEPPRA": 12.087341520354796, "LEVETIRACETAM": 45.35319020774524, "SPIKEVAX": 0.2143672555411316, "TOZINAMERAN": 0.587517296077266, "VAXZEVRIA": 0.2091458843019362, "null": 1.657954732539484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10950.json
new file mode 100644
index 00000000000..4aab17dd23b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10950.json
@@ -0,0 +1 @@
+{"null": 2.1571591563082437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10951.json
new file mode 100644
index 00000000000..964c6109c85
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10951.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 1.7354391810707022, "null": 0.2862409193252258}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10952.json
new file mode 100644
index 00000000000..75be551fe47
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10952.json
@@ -0,0 +1 @@
+{"BELIMUMAB": 120.83288024406104, "CICLOSPORIN": 0.8927337439584712, "COMIRNATY": 0.1639960047367255, "CONTRAST": 325.4943185846071, "HUMIRA": 3.67990042660381, "INSULIN": 2.524493414796467, "NEXAVAR": 1.14641898051387, "OPTIMARK": 465.0880855715105, "SPIKEVAX": 0.2818243720330273, "STIVARGA": 7.926535035729247, "SUTENT": 0.5536986179380431, "VAXZEVRIA": 0.1693498835348973, "null": 0.8897208778451796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10953.json
new file mode 100644
index 00000000000..2d4aa6d86ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10953.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.3579051547501488, "ARAVA": 0.7356357644459696, "AZATHIOPRINE": 8.175209444210195, "BENLYSTA": 3.23189915070601, "BUDESONIDE": 0.8408437661752467, "CICLOSPORIN": 4.121370166480782, "CIMZIA": 2.173030373607651, "COMIRNATY": 0.1873174310709666, "COSENTYX": 2.7944377512189345, "CYTARABINE": 2.941933707968871, "ENBREL": 1.686613888425334, "ENTYVIO": 3.633803981839222, "HIZENTRA": 7.772037317914322, "HUMALOG": 0.5885926711303608, "HYDROCORTISONE": 11.534978934134068, "IBRANCE": 1.125170716253381, "JARDIANCE": 0.9761265395324908, "LANTUS": 0.6770286789534157, "LEVOFLOXACIN": 2.5395787244776584, "MEPOLIZUMAB": 1.704055720328575, "MYCOPHENOLATE": 6.338628070887749, "NEULASTA": 3.108887215642873, "NEXAVAR": 1.5650665549540443, "OMALIZUMAB": 1.688185326341758, "OPSUMIT": 2.24998793086501, "PEGASYS": 2.1935926577847207, "PEGINTRON": 1.3396717901533914, "PEMBROLIZUMAB": 3.2698175091552164, "ROACTEMRA": 8.2870042268022, "SIMPONI": 6.172888397911713, "SPIKEVAX": 0.3732887315633186, "STELARA": 2.9391541659415528, "SUTENT": 0.8832571398934842, "TOZINAMERAN": 0.6130037896897605, "VAXZEVRIA": 0.2329031975963218, "XELJANZ": 5.162457437892608, "XOLAIR": 3.342033417534267, "ZOSTAVAX": 2.312172346508956, "null": 0.7358386069433285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10954.json
new file mode 100644
index 00000000000..00276e3ca62
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10954.json
@@ -0,0 +1 @@
+{"ARAVA": 1.2240958325526312, "CICLOSPORIN": 3.905804346335154, "COMIRNATY": 0.1973017167595027, "COSENTYX": 3.93673949102188, "HUMALOG": 1.6060171472289255, "KEPPRA": 1.396217970711183, "LANTUS": 1.0688663226267114, "LEVOFLOXACIN": 5.487739044247254, "PEGASYS": 1.1344734039914104, "SPIKEVAX": 0.1300840023979998, "STIVARGA": 3.837779109460167, "SUTENT": 2.56417364934112, "TOZINAMERAN": 0.5009445588619467, "VAXZEVRIA": 0.2234089911275489, "null": 1.8946311751735927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10955.json
new file mode 100644
index 00000000000..d4338c7c3a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10955.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.938664819556824, "AIMOVIG": 1.3182699783657883, "ALDARA": 17.70122601436196, "AUBAGIO": 0.9444194238955448, "BUPRENORPHINE": 4.574671103096947, "CIMZIA": 1.3194439172136647, "COMIRNATY": 0.5205009449024905, "COSENTYX": 1.2074994932961596, "CYMBALTA": 0.4916690687399109, "ELIQUIS": 0.5767852606147774, "ENTRESTO": 0.6781287948595112, "ENTYVIO": 1.9754874544244367, "EVRA": 18.608065985300453, "FORSTEO": 0.7785841499859084, "HUMIRA": 1.0003721749170031, "HYDROCORTISONE": 7.351212524133766, "IBRANCE": 1.0305750480352065, "IBUPROFEN": 1.0550030845503904, "JARDIANCE": 1.3560682008391802, "KEPPRA": 0.7498147897365398, "LANTUS": 0.4697152139253774, "MEPOLIZUMAB": 1.1327430767601807, "NEXAVAR": 0.9177244292729112, "OPSUMIT": 1.1281797230852153, "PEGASYS": 1.5303119736583009, "PLAVIX": 0.8655733647790183, "RINVOQ": 1.3554648719053233, "SHINGRIX": 2.085858564606795, "SPIKEVAX": 0.6364719628236684, "STELARA": 0.6509228716119051, "SUTENT": 2.929851122523308, "TOZINAMERAN": 0.973108999724274, "VAXZEVRIA": 0.5411885935920087, "XELJANZ": 0.7093831319065808, "XOLAIR": 0.9884882791058934, "ZOSTAVAX": 1.5696203465246952, "null": 1.9326406360508777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10956.json
new file mode 100644
index 00000000000..0f34a047937
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10956.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.8125418685373303, "ARAVA": 1.9583350059821345, "AUBAGIO": 0.7854776374575614, "AZATHIOPRINE": 2.693630188248217, "BENLYSTA": 2.3359975287312174, "BUPRENORPHINE": 1.1239097945890406, "CHAMPIX": 0.6594186232809064, "CIMZIA": 0.5533502188086455, "CLOPIDOGREL": 1.375196409553601, "COLLAGENASE": 564.5997339138858, "COMIRNATY": 0.111192474851882, "COSENTYX": 0.5648143836338423, "CYMBALTA": 3.4796458034779367, "ELIQUIS": 7.682496664267817, "FORXIGA": 1.5070366820389165, "GARDASIL": 2.081268315813245, "HEMLIBRA": 15.78821221592371, "HIZENTRA": 1.7768142118084578, "HUMALOG": 1.3706555270428704, "HUMIRA": 1.0543387702499163, "IBRANCE": 0.860481184754567, "IBUPROFEN": 4.153675847094446, "JANUVIA": 0.9498010914327556, "JARDIANCE": 0.6036812811759815, "KEPPRA": 3.0578497837066934, "LANTUS": 1.448134731144516, "MEPOLIZUMAB": 3.968381482933376, "METHOTREXATE": 4.486160640009123, "MICARDIS": 2.301432890653256, "NUCALA": 2.062495959596426, "OPSUMIT": 0.895429660615083, "PEGASYS": 2.036222775639738, "PEGINTRON": 1.5510676791048488, "PLAVIX": 1.4271952089378, "REMICADE": 4.823626113905671, "REVATIO": 2.469501024733876, "RIBAVIRIN": 3.022576464560005, "RITUXIMAB": 2.003947404509688, "SIMPONI": 1.5088973107467192, "SPIKEVAX": 0.2423911978231563, "STELARA": 0.5635957121124036, "SUBOXONE": 2.763226275155497, "SUTENT": 0.8542582305241622, "TAMIFLU": 1.2158057119944592, "TOZINAMERAN": 0.6155528885130286, "TRELEGY": 1.495293717160105, "VAXZEVRIA": 0.0388365353854526, "XELJANZ": 2.174117024353873, "XIAPEX": 81.29900011033402, "XTANDI": 1.0255702231077723, "XYREM": 4.640391406402893, "ZOSTAVAX": 1.2780645918807634, "ZYPREXA": 1.867187582752297, "null": 1.3080859873912014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10957.json
new file mode 100644
index 00000000000..10dee1e9970
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10957.json
@@ -0,0 +1 @@
+{"null": 0.9225583663233016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10958.json
new file mode 100644
index 00000000000..1a74fda837a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10958.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.387816695108497, "ABATACEPT": 0.5792879595822168, "ADALIMUMAB": 0.1761134748373249, "AFINITOR": 0.9650361069505384, "ALDARA": 4.547923062012956, "ALEMTUZUMAB": 1.0122441648005238, "AMIKACIN": 3.640030679547249, "APIDRA": 1.0448366356161218, "APREMILAST": 1.566503699878093, "ARANESP": 0.3896435967785145, "ARAVA": 0.583546563231653, "ASPARAGINASE": 1.7382835951133473, "ATRIPLA": 0.0567554828937025, "AUBAGIO": 1.312886813756715, "AZATHIOPRINE": 2.6755028007364663, "BASILIXIMAB": 4.000702097071331, "BELIMUMAB": 4.764061773365795, "BENLYSTA": 2.184004233537326, "BEVACIZUMAB": 0.562679143827918, "BIKTARVY": 2.11391998122753, "BRAFTOVI": 1.0802962493615182, "BRINTELLIX": 0.4678877765818904, "BUDESONIDE": 6.897497900967289, "BUPIVACAINE": 1.608794398182182, "BUPRENORPHINE": 0.3543130284360781, "CABOMETYX": 1.0179189079226143, "CAELYX": 2.308551366460995, "CANCIDAS": 4.224056028500778, "CAPECITABINE": 0.779347815849958, "CASPOFUNGIN": 5.240745149143815, "CELECOXIB": 2.9734036878540904, "CELLCEPT": 0.9010271193138611, "CETUXIMAB": 4.72614953093795, "CHAMPIX": 0.5779645568704772, "CICLOSPORIN": 6.118208826473684, "CIMZIA": 0.6979961842917739, "CLOPIDOGREL": 1.0009378104139548, "COAPROVEL": 1.491696936082599, "COMIRNATY": 0.222089171539669, "CONTRAST": 6.945824595197582, "COSENTYX": 8.077887597420714, "COTELLIC": 2.48213174438987, "CUBICIN": 1.7657067842974594, "CYMBALTA": 0.2256981221067556, "CYTARABINE": 2.172306088148208, "DEXAMETHASONE": 2.0859224927568087, "DOLUTEGRAVIR": 4.152409441463069, "DOXORUBICIN": 1.6528683393910075, "EFAVIRENZ": 12.2005873435129, "ELIQUIS": 0.4382522033867755, "EMEND": 2.7789558861475787, "ENBREL": 1.1802742583310968, "ENOXAPARIN": 2.6459952334587684, "ENTRESTO": 0.7638745753925402, "ENTYVIO": 0.6850632523027057, "ERTAPENEM": 18.330004567941774, "ESBRIET": 1.0605001050280236, "EXFORGE": 0.5768153058035732, "EXJADE": 0.9676519957165138, "FASENRA": 0.617992900632162, "FASLODEX": 0.6534398726667826, "FILGRASTIM": 2.3315305593421614, "FORSTEO": 0.4214025195416555, "FYCOMPA": 2.007819986359565, "GALVUS": 1.9616136977894525, "GARDASIL": 0.5237260367712854, "HIZENTRA": 1.430070501777703, "HUMALOG": 0.2185860716621249, "HUMAN": 1.1840350147708576, "HUMIRA": 2.189345154213997, "HYDROCORTISONE": 3.211876117406701, "IBRANCE": 1.183888499254735, "IBUPROFEN": 1.6411249643086243, "ICLUSIG": 2.024141604145083, "IMIQUIMOD": 11.612426866497596, "INCIVO": 3.320614504559782, "INLYTA": 2.9740811126629665, "INSULIN": 1.046432720942038, "IRINOTECAN": 1.0572679137688237, "JAKAVI": 2.5701609077486656, "JANUMET": 0.4674279681359176, "JARDIANCE": 0.3587392851303178, "KEPPRA": 0.4292798387871602, "KEYTRUDA": 0.6083390622832004, "KISQALI": 1.521466791819075, "KYMRIAH": 1.226108584934625, "LAMIVUDINE": 9.466962784844132, "LANTUS": 0.3783678528596036, "LEFLUNOMIDE": 2.312087001880263, "LEMTRADA": 1.4378841805789762, "LEVETIRACETAM": 0.591389246876872, "LEVOFLOXACIN": 1.422086102945537, "LYRICA": 1.0763403271583838, "MEKINIST": 2.5084289753399736, "MEPOLIZUMAB": 1.4122425779752552, "METHOTREXATE": 2.440862231739434, "MYCOPHENOLATE": 3.4356428215250565, "NEXAVAR": 2.8528256510139136, "NILOTINIB": 2.745255098152901, "NOT": 1.2818487241050829, "NUCALA": 1.3619703245378256, "OCALIVA": 2.2192977404845484, "OFEV": 0.6827101476652455, "OLANZAPINE": 0.8394938075605571, "OMALIZUMAB": 1.8626007106131512, "OPDIVO": 0.4538788125804149, "OPTIMARK": 11.374394007831654, "PANTOPRAZOLE": 1.983040445291544, "PEGASYS": 1.5759497013636108, "PEGINTERFERON": 2.376360741241249, "PEGINTRON": 0.3705770383931795, "PEMBROLIZUMAB": 1.2531966987718095, "PRIVIGEN": 0.7052451345991688, "QUTENZA": 4.076096657856376, "RIBAVIRIN": 0.812324871804988, "RINVOQ": 3.114191853322711, "RITUXIMAB": 1.0568745754514737, "ROACTEMRA": 1.4205330680875146, "RUXOLITINIB": 2.854450858334013, "SAXENDA": 0.55118960826523, "SHINGRIX": 3.7728462365479913, "SIMPONI": 1.2178532420192731, "SKYRIZI": 3.21380542299721, "SOLIRIS": 1.0863561710598657, "SPIKEVAX": 0.1610347215269549, "STELARA": 1.6175196936621683, "STIVARGA": 1.4186855966135072, "SUTENT": 3.363434436544172, "TACROLIMUS": 3.007428543531706, "TASIGNA": 1.3849939963632785, "TOZINAMERAN": 0.4952471248120909, "TREMFYA": 2.0874456861897484, "UPADACITINIB": 8.410892218998722, "VAXZEVRIA": 0.1374419023042351, "VECTIBIX": 5.616056866047897, "VFEND": 0.7711459115450414, "VIAGRA": 0.3880616554819973, "VORICONAZOLE": 3.1239454473472112, "VOTRIENT": 0.3938502709846445, "XELJANZ": 2.18653659633868, "XOLAIR": 2.280642946835563, "ZELBORAF": 4.029432384047933, "ZOSTAVAX": 2.1199487833423585, "ZYPREXA": 0.534790904980751, "null": 1.0884935321236948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10959.json
new file mode 100644
index 00000000000..9c0747fe8c8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10959.json
@@ -0,0 +1 @@
+{"null": 0.569459501492322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1096.json
index 71f9e495ff3..4b88bd9bcf7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1096.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1096.json
@@ -1 +1 @@
-{"ABATACEPT": 15.28101222462559, "ARAVA": 9.490800288893864, "ARIPIPRAZOLE": 37.47635948954606, "ENBREL": 8.471494290177265, "INTELENCE": 196.05906906058885}
\ No newline at end of file
+{"null": 1.0485986729839327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10960.json
new file mode 100644
index 00000000000..ce1f362d4b9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10960.json
@@ -0,0 +1 @@
+{"null": 0.7163965810284204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10961.json
new file mode 100644
index 00000000000..1910457743d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10961.json
@@ -0,0 +1 @@
+{"null": 0.8074973192244699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10962.json
new file mode 100644
index 00000000000..c6945765257
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10962.json
@@ -0,0 +1 @@
+{"null": 4.084932439899535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10963.json
new file mode 100644
index 00000000000..264b1d4bbb0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10963.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 3.69273722596366, "ARAVA": 1.040570462834724, "AZATHIOPRINE": 3.2416246899638077, "BYDUREON": 6.701237880891941, "CAPECITABINE": 3.14861897872978, "CELLCEPT": 1.467122095710912, "CICLOSPORIN": 10.94852003973032, "CLOPIDOGREL": 0.7125597930363978, "COMIRNATY": 0.4255124724982947, "COSENTYX": 2.2707119276358063, "CYTARABINE": 3.671883340394436, "DEXAMETHASONE": 2.872356431873686, "ELIQUIS": 0.3890818016756325, "ENBREL": 1.3871447851806482, "FASLODEX": 2.422340461629647, "FORSTEO": 1.183539342597427, "HIZENTRA": 2.56211388630661, "HUMALOG": 1.2638500869034213, "HUMIRA": 3.2314891267894343, "IBRANCE": 0.6224680692930429, "INSULIN": 3.797239320992056, "LAMIVUDINE": 6.266463227898819, "LANTUS": 1.0581493730244809, "LEVOFLOXACIN": 1.7176078133624872, "MEKINIST": 3.648037225245433, "METHOTREXATE": 2.0742811791635, "MYCOPHENOLATE": 7.927424619355481, "NEXAVAR": 1.1797767970156223, "OMALIZUMAB": 1.7056533927387212, "OPTIMARK": 15.225302075083167, "PEGASYS": 0.9047603233631416, "PEGINTERFERON": 2.8792148646658746, "SIMPONI": 1.7031243637546274, "SPIKEVAX": 0.4912585025819716, "STELARA": 1.2629072907089745, "SUTENT": 0.4089663076608978, "TOZINAMERAN": 0.7695241752024486, "VAXZEVRIA": 0.3162815624870237, "XELJANZ": 0.6470464096733661, "XOLAIR": 0.8234023796183775, "ZELBORAF": 6.387952162329265, "null": 0.870940266131508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10964.json
new file mode 100644
index 00000000000..103e19caa55
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10964.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.639872305269978, "ADALIMUMAB": 0.5945469781592643, "ARAVA": 0.2783292394967915, "AVASTIN": 1.5625187176785271, "BETAFERON": 29.481193262851587, "CASPOFUNGIN": 6.663962703438559, "CICLOSPORIN": 4.194172441771924, "CLOPIDOGREL": 0.7353203761235168, "COMIRNATY": 0.0444406955693062, "CYTARABINE": 1.6795159423981512, "DEXAMETHASONE": 1.6486033784820084, "EFAVIRENZ": 7.785549729167236, "ELIQUIS": 1.6202941617071869, "ENBREL": 13.645931659907186, "ENOXAPARIN": 17.22136373769157, "JAKAVI": 1.4530849162909871, "JARDIANCE": 1.043527759694127, "KEYTRUDA": 0.3969008374126629, "NEXAVAR": 2.8949519108641115, "OPTIMARK": 4.203269806868773, "PEGINTRON": 3.44230165991304, "PLAVIX": 0.7999186993882391, "ROACTEMRA": 2.6450791095626647, "SUTENT": 0.8014313576474728, "TERIPARATIDE": 19.31323140631608, "VAXZEVRIA": 0.0220693215224782, "null": 3.101685813245376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10965.json
new file mode 100644
index 00000000000..79d0472f7d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10965.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 41.513990773463725, "null": 0.9063174312708174}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10966.json
new file mode 100644
index 00000000000..b5ec7b344c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10966.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.814715157246076, "ERTAPENEM": 151.4019220382776, "FASLODEX": 4.505077567485986, "FORSTEO": 2.112505025176776, "HUMALOG": 1.836631872340062, "JARDIANCE": 4.7021036330959385, "SAXENDA": 6.3898460015954255, "SPIKEVAX": 0.428442914512037, "SUTENT": 0.8357768038700625, "TOZINAMERAN": 0.6109521249673932, "VAXZEVRIA": 0.4795234733606438, "null": 1.4779503519237775}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10967.json
new file mode 100644
index 00000000000..707554a3ff1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10967.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4323608207506083, "COSENTYX": 4.726313460317808, "OPTIMARK": 6.21524085008329, "SPIKEVAX": 0.1891710361761552, "VAXZEVRIA": 0.2042382537593293, "XOLAIR": 5.874135795690657, "null": 2.0242655931422004}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10968.json
new file mode 100644
index 00000000000..ea1c7b4607e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10968.json
@@ -0,0 +1 @@
+{"ARAVA": 1.5951283069583533, "BRAFTOVI": 10.492121021974182, "CELLCEPT": 4.691276916849734, "CICLOSPORIN": 7.065689278192477, "COMIRNATY": 0.3459517628206409, "ELIQUIS": 1.0464713017895286, "ENBREL": 3.62250935697878, "GARDASIL": 5.957155275798578, "JAKAVI": 4.191438405294417, "NEXAVAR": 2.328719717175764, "SPIKEVAX": 0.1820286725158624, "STELARA": 3.2685370513751564, "SUTENT": 3.456149548513844, "TAFINLAR": 56.4605016308825, "VAXZEVRIA": 0.1351352375485802, "VEMURAFENIB": 195.36745689367575, "XELJANZ": 2.4223253582024804, "ZELBORAF": 210.90135374181688, "ZOSTAVAX": 2.1998176548498143, "null": 0.4573372071804793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10969.json
new file mode 100644
index 00000000000..d82b9f25360
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10969.json
@@ -0,0 +1 @@
+{"AFINITOR": 1.8064470032079225, "APIDRA": 1.7339910156317366, "CICLOSPORIN": 10.995444371486478, "CIMZIA": 0.9900851954105424, "COMIRNATY": 0.1974724415023001, "CONTRAST": 75.81421967151907, "COSENTYX": 21.42256586208632, "ELIQUIS": 0.4458665927347983, "ENTECAVIR": 14.51597262873656, "FASENRA": 2.3068494195753857, "HUMIRA": 3.354314154454817, "LEFLUNOMIDE": 12.352113658068822, "LEVOFLOXACIN": 0.8694239779315398, "METHOTREXATE": 3.0723849447232734, "MYCOPHENOLATE": 5.740953783497286, "NEXAVAR": 0.7065097033434113, "OMALIZUMAB": 13.452309460882274, "OPTIMARK": 41.0394106745083, "PEGINTERFERON": 6.559127872448173, "RENVELA": 346.5218211341869, "RINVOQ": 4.581448387236343, "SHINGRIX": 1.6690584385213525, "SKYRIZI": 19.343395065319918, "SPIKEVAX": 0.1726846513723383, "STELARA": 2.143091330658451, "TOZINAMERAN": 0.1231539444371681, "TREMFYA": 5.009081982317691, "VAXZEVRIA": 0.0848299539320744, "XOLAIR": 4.687672818951868, "null": 1.4589659552180805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1097.json
index fa64d0c3cc0..e36c14702f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1097.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1097.json
@@ -1 +1 @@
-{"null": 8.826875229204319}
\ No newline at end of file
+{"COMIRNATY": 0.4688062371972107, "METHOTREXATE": 153.45414717964348, "null": 0.4679488342317785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10970.json
new file mode 100644
index 00000000000..7b2e4b0d1db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10970.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 2.0084283033524843, "ABATACEPT": 0.2594975136857569, "ADALIMUMAB": 0.0516420295456316, "AFINITOR": 0.6047690699442594, "AIMOVIG": 1.7443716435133696, "ALDARA": 11.193033437008417, "ALIMTA": 1.43395074200109, "AMELUZ": 85.10522020518985, "ARANESP": 0.474913939999339, "ARAVA": 0.5260637174211318, "AUBAGIO": 1.2053506433670744, "AXITINIB": 2.8172524322460224, "BENLYSTA": 0.4663213816504893, "BETAFERON": 5.756386793338486, "BRINTELLIX": 0.4601322580044709, "BUDESONIDE": 0.2588521085284281, "BUPRENORPHINE": 1.1672201443243837, "BYETTA": 1.1194310202804352, "CABOMETYX": 0.6660549027956513, "CAELYX": 4.8504101124817645, "CANNABIDIOL": 8.68376266470596, "CAPECITABINE": 0.8574878698792514, "CHAMPIX": 0.8928259004561687, "CIMZIA": 1.1668348950284455, "CLOPIDOGREL": 0.7757648082250915, "COMIRNATY": 0.5876321375838562, "COSENTYX": 3.1231230740501377, "COTELLIC": 5.304706672132148, "CYMBALTA": 0.1739613752521528, "DOCETAXEL": 0.7359842852938152, "ELIQUIS": 0.2942591909853784, "ENBREL": 0.3149386761421194, "ENTRESTO": 0.6329301974573373, "ENTYVIO": 2.029156262539256, "ERBITUX": 2.747788583345047, "ERLEADA": 6.59459687899933, "ESBRIET": 2.764094156532044, "EVRA": 4.00291753989474, "EXFORGE": 0.71005772288846, "FASENRA": 2.4478670604501267, "FASLODEX": 0.963971320819594, "FENTANYL": 0.5907902361856586, "GARDASIL": 0.2492285092758957, "HERCEPTIN": 1.2680782639168833, "HIZENTRA": 2.4062420441164867, "HUMALOG": 0.3855536112554064, "HUMIRA": 2.000617164451952, "IBRANCE": 0.1695215295923094, "ICLUSIG": 1.9246284730778136, "IDACIO": 13.726564452481314, "IMIQUIMOD": 15.8383975256756, "INCIVO": 7.345750598595121, "IRESSA": 1.0829537429212717, "IRINOTECAN": 1.6325159917129433, "JANUMET": 0.6680548277962142, "JARDIANCE": 0.9349813648299262, "KEPPRA": 0.3328117540348672, "KEYTRUDA": 1.152083968958674, "KISQALI": 2.3447665588577515, "LANTUS": 0.383688175470841, "LEMTRADA": 1.2408985994771566, "LEVEMIR": 3.3822057406815493, "LEVETIRACETAM": 0.9622577125696918, "LEVOFLOXACIN": 0.6907941649073869, "LYRICA": 0.4264899363182908, "MEKINIST": 0.9918954240739476, "MEPOLIZUMAB": 0.4140934225143959, "METHOTREXATE": 0.7310152780948733, "MMRVAXPRO": 1.0188438174469847, "MODERNA": 3.3949171632973134, "NEXAVAR": 3.3555249558991327, "NIMENRIX": 1.4335073387970534, "NUCALA": 0.8532834162171034, "PEGASYS": 0.674144407497174, "PEGINTERFERON": 2.527961094190675, "PEGINTRON": 1.7144246616365078, "PEMBROLIZUMAB": 1.891116723625456, "PLAVIX": 0.3825407839195149, "PLEGRIDY": 5.574485548038685, "PRIVIGEN": 2.6751991634570254, "QUTENZA": 5.953423007477755, "ROACTEMRA": 4.598830024059256, "SAXENDA": 2.556655108922498, "SHINGRIX": 1.7673692990682406, "SIMPONI": 0.9251527663094086, "SORAFENIB": 4.758319618050393, "SPIKEVAX": 1.599869425848154, "STELARA": 1.0669767214538448, "STIVARGA": 2.5102875397970736, "SUTENT": 0.6904627878826699, "TAGRISSO": 1.5269092116108716, "TAMIFLU": 0.6050156238340076, "TEMOZOLOMIDE": 3.122019542635341, "TOZINAMERAN": 0.3397972613269358, "TREMFYA": 0.9567645560396704, "TRULICITY": 0.734321463976278, "VAXZEVRIA": 0.4561699318467744, "VECTIBIX": 3.559296880273886, "VFEND": 0.5896738591040441, "VICTOZA": 0.6442492545382973, "VOTRIENT": 0.5273462673214362, "XOLAIR": 1.2626401058386638, "ZELBORAF": 4.691425979020631, "ZYCLARA": 19.03068767252705, "null": 1.2971877372090062}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10971.json
new file mode 100644
index 00000000000..7c8e97773d6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10971.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.0807880198232926, "SPIKEVAX": 1.0911051446956923, "SUTENT": 9.766567901227674, "TOZINAMERAN": 1.7338020904802818, "VAXZEVRIA": 2.469829479942589, "XOLAIR": 7.046871761810538, "null": 0.2915110668185302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10972.json
new file mode 100644
index 00000000000..84ff6db5b6b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10972.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 3.006354328425729, "COMIRNATY": 0.1382579774622305, "COSENTYX": 3.661556827481617, "GARDASIL": 10.109748111838549, "KALETRA": 11.070190004297276, "LOPINAVIR": 102.90567499587092, "METHOTREXATE": 4.221777588602435, "RITONAVIR": 159.8712553717871, "SPIKEVAX": 0.1743318193430147, "VAXZEVRIA": 0.1497489825095332, "ZYPREXA": 4.268365028069802, "null": 1.9873643486066648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10973.json
new file mode 100644
index 00000000000..5fcabe2c36b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10973.json
@@ -0,0 +1 @@
+{"AIMOVIG": 2.0132686307088683, "COMIRNATY": 0.850782830261008, "COSENTYX": 1.806174574002926, "HYDROCORTISONE": 8.634549363730603, "IBUPROFEN": 3.0046752110745136, "NEXAVAR": 2.223583113398042, "OPTIMARK": 30.4873981787522, "SPIKEVAX": 1.2514111384677276, "STIVARGA": 7.935948615628367, "TOZINAMERAN": 1.4859784778864964, "VAXZEVRIA": 0.5582812919622779, "XOLAIR": 3.0656877192478333, "null": 1.307227817180618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10974.json
new file mode 100644
index 00000000000..5db70973e3c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10974.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7443800530562696, "SPIKEVAX": 0.8105640045750268, "TOZINAMERAN": 1.1889311221982068, "VAXZEVRIA": 12.055694522130567}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10975.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10975.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10976.json
new file mode 100644
index 00000000000..56c69e971e6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10976.json
@@ -0,0 +1 @@
+{"null": 14.08054211044102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10977.json
new file mode 100644
index 00000000000..67d7bd3603e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10977.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 6.525128425823015, "COMIRNATY": 0.0814230268169766, "FENTANYL": 3.6837232257327024, "INSULIN": 9.39358039773172, "null": 6.840314813950021}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10978.json
new file mode 100644
index 00000000000..ce2fb374c11
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10978.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6932588723863176, "SPIKEVAX": 0.9283059103436668, "null": 1.7594257260330517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10979.json
new file mode 100644
index 00000000000..9ea09332724
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10979.json
@@ -0,0 +1 @@
+{"AMELUZ": 91.43288120731528, "COMIRNATY": 0.3118979668197097, "CONTRAST": 277.06006709871093, "OPTIMARK": 376.5401583305209, "SPIKEVAX": 0.3823866830583446, "TOZINAMERAN": 0.8260713452102243, "VAXZEVRIA": 0.3410797799365845, "null": 0.9899301250595998}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1098.json
index 479150177d5..6106b40dc6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1098.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1098.json
@@ -1 +1 @@
-{"null": 1.474794731145718}
\ No newline at end of file
+{"null": 3.7846578968294087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10980.json
new file mode 100644
index 00000000000..7fa2b4c0cb3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10980.json
@@ -0,0 +1 @@
+{"AFINITOR": 2.658006413235821, "ALIMTA": 8.05181352612892, "ATEZOLIZUMAB": 34.05166204559813, "AVASTIN": 3.5544058480220126, "BEVACIZUMAB": 17.465644576033498, "BUSULFAN": 14.112464618849586, "CABOMETYX": 13.857098392532317, "CAELYX": 23.488090680243136, "CAPECITABINE": 12.778642912975087, "CETUXIMAB": 139.75007226018678, "CICLOSPORIN": 1.1271094986970909, "COBIMETINIB": 178.96088006931797, "COTELLIC": 64.73812125996253, "CYTARABINE": 4.130102142079066, "DABRAFENIB": 23.81092598567872, "DEXAMETHASONE": 1.4339768852223642, "DOCETAXEL": 10.563897447393977, "ERBITUX": 32.39811789861671, "ERLEADA": 12.211511580330514, "FILGRASTIM": 7.54373576629593, "GEFITINIB": 48.78450310869522, "IBRANCE": 0.7832137236207406, "ICLUSIG": 5.523239062534077, "IMATINIB": 14.214434715056305, "INLYTA": 2.5723262489521312, "IPILIMUMAB": 16.50546347547642, "IRESSA": 11.147492837682323, "IRINOTECAN": 32.02736682467039, "KEYTRUDA": 6.79551368060786, "KISQALI": 7.598996909707168, "MEKINIST": 6.580342247647291, "NEXAVAR": 19.789406420087783, "OPDIVO": 5.198866120923339, "OSIMERTINIB": 23.382472701422863, "PANITUMUMAB": 211.4689891667936, "PEMBROLIZUMAB": 24.155496534535125, "PEMETREXED": 16.70435932295389, "RIBOCICLIB": 10.68621909425426, "SORAFENIB": 48.99359915368554, "STIVARGA": 22.68918971133137, "SUTENT": 5.448366793062228, "TAGRISSO": 7.815781450501984, "TRAMETINIB": 60.95514494200553, "VECTIBIX": 206.6784266870236, "VEMURAFENIB": 96.32497356459966, "VOTRIENT": 4.245703711273653, "ZELBORAF": 30.49721068217535, "null": 0.095821222829343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10981.json
new file mode 100644
index 00000000000..6dfe38754e6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10981.json
@@ -0,0 +1 @@
+{"null": 2.228621889244715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10982.json
new file mode 100644
index 00000000000..dc80e12d2d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10982.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10983.json
new file mode 100644
index 00000000000..8f1e2e24437
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10983.json
@@ -0,0 +1 @@
+{"null": 1.3498743603753671}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10984.json
new file mode 100644
index 00000000000..d78b86133a4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10984.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.103743477786441, "AMINOSALICYLIC": 4.33072139927645, "ARAVA": 2.8358556089888243, "BENLYSTA": 1.8127370747454168, "COMIRNATY": 0.8111575901148766, "CYMBALTA": 0.324366526506005, "GARDASIL": 1.780661114809268, "HYDROCORTISONE": 2.837085925833804, "LACOSAMIDE": 4.352616815764342, "MENVEO": 12.859470211311724, "MMRVAXPRO": 3.535789791234909, "NIMENRIX": 2.3841906876887364, "OCRELIZUMAB": 3.994068374846879, "OPTIMARK": 2.7263703657254266, "PEGINTRON": 0.7514106625283578, "SHINGRIX": 7.366464822355538, "SPIKEVAX": 2.1369045543592877, "STELARA": 0.8140124991749694, "STIVARGA": 2.887390944099752, "TOZINAMERAN": 2.144832538028975, "VAXZEVRIA": 1.7545611754778387, "ZOSTAVAX": 1.717201118196071, "null": 0.807092830108366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10985.json
new file mode 100644
index 00000000000..71ab890219f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10985.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5454438300199073, "HYDROCORTISONE": 213.60008751670057, "IMIQUIMOD": 219.5377969668076, "SPIKEVAX": 0.4142927511503812, "STIVARGA": 12.210612125245008, "TOZINAMERAN": 1.0683021618714774, "VAXZEVRIA": 0.2033693882779954, "null": 1.3848739340488148}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10986.json
new file mode 100644
index 00000000000..d2f7ffa94dd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10986.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3643576730817042, "HEXYON": 634.1460256189082, "INFANRIX": 51.72130811301144, "MMRVAXPRO": 77.01037602335396, "NEXAVAR": 3.6028465880742018, "PREVENAR": 46.69086228118645, "SUTENT": 3.636360983623124, "VAXZEVRIA": 0.1665039349180193, "null": 0.586185862045833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10987.json
new file mode 100644
index 00000000000..9fed65ddd0a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10987.json
@@ -0,0 +1 @@
+{"ATRIPLA": 1.0684824582155483, "COMIRNATY": 0.2651139714949254, "COSENTYX": 4.696462918972237, "HYDROCORTISONE": 37.797468495424965, "OPTIMARK": 12.567536580225786, "PEGASYS": 1.969057556389152, "SPIKEVAX": 0.3011478726447532, "TOZINAMERAN": 0.7554625741669747, "null": 1.3912612133636446}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10988.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10988.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10989.json
new file mode 100644
index 00000000000..2cca4e7d978
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10989.json
@@ -0,0 +1 @@
+{"ATRIPLA": 2.4086552687920872, "COMIRNATY": 0.0786246506950253, "ELIQUIS": 3.236470337022713, "GARDASIL": 4.728530957616817, "SPIKEVAX": 0.2706837765923422, "SUBOXONE": 8.289863718694649, "null": 1.301834421375063}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1099.json
index 0b1f0bea34a..b5078413f2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1099.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1099.json
@@ -1 +1 @@
-{"null": 3.087517880022931}
\ No newline at end of file
+{"COMIRNATY": 0.2070018537564784, "ENALAPRIL": 775.9646085531555, "ENTRESTO": 21.46485247400659, "null": 1.174772381958694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10990.json
new file mode 100644
index 00000000000..ea017ad7c0d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10990.json
@@ -0,0 +1 @@
+{"null": 0.977120461050014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10991.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10991.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10992.json
new file mode 100644
index 00000000000..d444a1ac7f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10992.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.2890500739080963, "ALENDRONATE": 109.33563566879263, "APIXABAN": 66.38592779086599, "ARIPIPRAZOLE": 1.7707730090311984, "ATRIPLA": 0.0877578991585931, "AVAMYS": 17.27742857981414, "AVANDIA": 1.7569437876725835, "AVONEX": 17.603670599750913, "BRILIQUE": 8.134990669995823, "BUDESONIDE": 1.0549257383345931, "BUPIVACAINE": 3.3874571243987703, "BYDUREON": 1.2244301643085036, "BYETTA": 4.130673385689277, "CHAMPIX": 0.5443338362140229, "CIALIS": 6.560609921974558, "CIMZIA": 0.2798277667930273, "CLOPIDOGREL": 3.416591233167537, "COMIRNATY": 0.1686609988308563, "COSENTYX": 1.351520314051763, "CYMBALTA": 1.6001709957181052, "DESLORATADINE": 8.04014145383151, "DULOXETINE": 5.09197009709474, "ELIQUIS": 2.974497235942815, "ENBREL": 1.2871810762731586, "ENTRESTO": 1.691278670376107, "ESOMEPRAZOLE": 4.184391072232984, "ETANERCEPT": 15.32454843707335, "FENTANYL": 0.7920851081268155, "HUMALOG": 2.530167354132853, "HUMIRA": 0.7922867330692597, "IBRANCE": 0.2864263296716248, "IBUPROFEN": 0.8355539761029765, "INCRUSE": 4.354449121455521, "IRBESARTAN": 2.5623859905842776, "JANUMET": 1.4801176872285793, "JANUVIA": 1.4221523385427672, "KEPPRA": 0.8596050992439944, "LANTUS": 1.0861897396324005, "LATUDA": 2.117410195905879, "LYRICA": 3.2693413975107064, "MELATONIN": 4.597825087607563, "MEPOLIZUMAB": 3.718737958159209, "NAGLAZYME": 9.122161743484908, "OLANZAPINE": 1.1314631090288507, "OMALIZUMAB": 1.4314876155873113, "OPSUMIT": 0.7454054835853098, "OPTIMARK": 1.0571416717881887, "PASIREOTIDE": 78.49920952748595, "PEGASYS": 0.4446453282793212, "PROPRANOLOL": 5.134308098719594, "REVATIO": 1.6387271821782212, "RINVOQ": 1.3602964666445252, "SOMATROPIN": 37.13542725004547, "SPIKEVAX": 0.1682384294063493, "STELARA": 0.3342279062061347, "SUBOXONE": 4.187819352751132, "TASIGNA": 1.001869526160903, "TOZINAMERAN": 0.3623021757108742, "TRULICITY": 1.154649785235604, "VAXZEVRIA": 0.1003697012213028, "VIAGRA": 2.6961250886741785, "XELJANZ": 0.7179533745136037, "XOLAIR": 1.5474020929051555, "XTANDI": 0.499622182324178, "XYREM": 24.397330689746223, "ZOSTAVAX": 5.140868820349772, "ZYPREXA": 3.55030746637523, "null": 1.0734879410088345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10993.json
new file mode 100644
index 00000000000..bdb4ebd470e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10993.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5265653957694435, "SIFROL": 148.13713456773235, "SPIKEVAX": 0.6074149835798887, "VAXZEVRIA": 0.2789483876271973, "null": 2.003385714974084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10994.json
new file mode 100644
index 00000000000..77deb54791a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10994.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8147471007105133, "CYMBALTA": 2.844736352961452, "KEPPRA": 2.77791416494186, "METHOTREXATE": 7.307693305337182, "SPIKEVAX": 0.7509707825735642, "TOZINAMERAN": 1.856616652885496, "VAXZEVRIA": 1.1505655248913498, "null": 0.7207647941021594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10995.json
new file mode 100644
index 00000000000..e28400bf694
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10995.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10996.json
new file mode 100644
index 00000000000..1d500b1938f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10996.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.2448290286156051, "ACLIDINIUM": 42.458103823346725, "AMINOSALICYLIC": 2.0674883309448844, "ANORO": 8.867796623997487, "APIXABAN": 64.73068932169508, "ARAVA": 0.0914125255549502, "ATRIPLA": 0.0607306279011416, "AVAMYS": 46.21453076288804, "AZATHIOPRINE": 3.641559683161069, "AZOPT": 61.5249815100347, "BENRALIZUMAB": 97.20943505285862, "BUDESONIDE": 25.558990202543665, "BUPRENORPHINE": 0.8680766302438392, "CANAGLIFLOZIN": 50.35233553209088, "CAYSTON": 244.8819808223313, "CIMZIA": 0.2400185706645735, "COMIRNATY": 0.0470982062350446, "DESLORATADINE": 23.36322839179094, "DEXAMETHASONE": 2.0451521204739187, "DUPIXENT": 7.551327766714572, "ELIQUIS": 1.8535882558603385, "ESOMEPRAZOLE": 2.448024163835955, "FASENRA": 2.4278551751898463, "FASLODEX": 0.5661150322866538, "FLUTICASONE": 26.73537109073033, "FORSTEO": 1.4207742207131593, "GLYCOPYRRONIUM": 134.64073509343035, "HUMALOG": 0.9470860441703084, "HYDROCORTISONE": 2.8873273515233966, "IBUPROFEN": 1.003942604452254, "INCRUSE": 18.40221145482263, "INSULIN": 6.920007003483999, "IRON": 7.098079055884357, "JANUVIA": 1.7051838882855053, "LEVOFLOXACIN": 0.5706426020603805, "LIRAGLUTIDE": 136.99039134176954, "MEPOLIZUMAB": 93.38205534841774, "NUCALA": 65.68343507466813, "OMALIZUMAB": 6.094390186721993, "PANTOPRAZOLE": 9.530156945897858, "TELMISARTAN": 19.626837093032712, "TOZINAMERAN": 0.1192980918180148, "TRELEGY": 3.2185667326933096, "TRULICITY": 0.8851316026243048, "UMECLIDINIUM": 70.01718651690337, "VARENICLINE": 31.60622341915452, "XELJANZ": 0.2332671719320718, "ZOSTAVAX": 0.4015902119477124, "null": 0.5327375573398365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10997.json
new file mode 100644
index 00000000000..a532695ab84
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10997.json
@@ -0,0 +1 @@
+{"COSENTYX": 143.64377407843767, "null": 0.8215158129056229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10998.json
new file mode 100644
index 00000000000..5f18608567f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10998.json
@@ -0,0 +1 @@
+{"ABATACEPT": 55.88231022858083, "ADALIMUMAB": 6.681001131829712, "APIXABAN": 18.42533342017377, "APREMILAST": 11.305619946130903, "ARAVA": 6.351521446452278, "CELLCEPT": 8.207025815350317, "CHLORHEXIDINE": 165.0232517719273, "CIMZIA": 46.3292055953065, "COMIRNATY": 0.0771575299520622, "DACLIZUMAB": 411.26380198328826, "ENBREL": 2.2475288067219874, "FORSTEO": 7.760791120764014, "HUMALOG": 1.2890070754000735, "TOZINAMERAN": 0.526139339316723, "TRULICITY": 2.4503251544825257, "XELJANZ": 1.115528473835529, "ZOSTAVAX": 1.7728532156196546, "null": 0.1840104634175683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10999.json
new file mode 100644
index 00000000000..04f5c42de15
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/10999.json
@@ -0,0 +1 @@
+{"DARBEPOETIN": 17149.396838288594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11.json
index 388bcb6d872..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.2122180515801977, "AFINITOR": 4.5474259602847695, "BYETTA": 10.884716350995316, "CIMZIA": 1.179437442575138, "FORSTEO": 4.254243176166805, "JANUMET": 4.246133578101267, "JANUVIA": 9.111805541926955, "KALETRA": 5.408047478773876, "LANTUS": 2.355554112374048, "XELJANZ": 2.884070979605181, "ZOSTAVAX": 5.164686893440604, "ZYPREXA": 1.7087230235173954, "null": 1.6893443698007904}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/110.json
index 4eceb3bab9e..121df68e6aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/110.json
@@ -1 +1 @@
-{"SOMAVERT": 1167.8586757180838, "null": 4.949096273395504}
\ No newline at end of file
+{"AIMOVIG": 16.4360003560904, "ARANESP": 1.709712771209816, "BENLYSTA": 3.4356332218278096, "BENZODIAZEPINE": 5.040554654149069, "BUPRENORPHINE": 0.9561856175354976, "CARIPRAZINE": 26.793883643369128, "CLOPIDOGREL": 1.1530961404867586, "COMIRNATY": 0.0109571291268995, "COSENTYX": 7.90980797807932, "CYMBALTA": 0.2736191165044379, "FENTANYL": 1.396750958669415, "GARDASIL": 0.2581431851511615, "GLIBENCLAMIDE": 9.795380822874098, "HUMALOG": 0.8717109155020664, "IBUPROFEN": 1.8689650838940035, "KEPPRA": 6.3313198248933, "LANTUS": 0.7171235617208591, "LEVETIRACETAM": 1.0132891840962026, "LYRICA": 0.64195810518997, "METHOTREXATE": 0.4890418596095984, "MICARDIS": 1.3469320782001075, "MMRVAXPRO": 0.3652111270847282, "NEULASTA": 5.244019986987424, "NINLARO": 5.489540689415383, "NUCALA": 3.519369823198464, "OLANZAPINE": 0.9721593797942664, "PEGASYS": 0.1553267617123968, "PEGINTRON": 0.2944541581973668, "PLAVIX": 0.2584731823908684, "QUTENZA": 15.709376464122007, "SIMPONI": 35.529132067159274, "STELARA": 5.365478909753827, "SUBOXONE": 5.538336475743187, "TESTOSTERONE": 12.080499856820271, "TOZINAMERAN": 0.0385290621074979, "TREMFYA": 58.69326288632909, "TRULICITY": 1.0776868217469684, "VAXZEVRIA": 0.0335168193733084, "VIAGRA": 0.8856261238482491, "VIMPAT": 4.240859210788143, "ZOSTAVAX": 0.7136638751643477, "ZYPADHERA": 1.9337724727857728, "ZYPREXA": 1.2989358781627591, "null": 2.719416208694733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1100.json
index 4c8ff0cef59..2e9a862c3f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1100.json
@@ -1 +1 @@
-{"CETRORELIX": 3972.331408983344, "FASLODEX": 18.73559942213892, "null": 3.71263744014569}
\ No newline at end of file
+{"ABATACEPT": 0.1700349210132269, "ABILIFY": 0.1915396696996582, "ACLASTA": 3.90011958111815, "ACLIDINIUM": 3.6820600394103296, "ADCIRCA": 1.1689707636168147, "ADEMPAS": 0.5106481439078544, "ADENURIC": 3.2486419813966, "AERIUS": 0.3894367564472764, "AFINITOR": 0.3335106860989777, "AIMOVIG": 0.2005319673203512, "ALENDRONATE": 13.452932723740984, "ALIMTA": 1.4996763013631187, "ALISKIREN": 0.784901538212426, "AMBRISENTAN": 1.2326649553490678, "ANAKINRA": 0.2031003303886314, "ANORO": 1.8418796342746908, "ANTIBIOTICS": 1.3251094013146472, "APIDRA": 0.4313269296204847, "APIXABAN": 5.224220318316744, "APROVEL": 0.8955759966554202, "ARANESP": 0.7700227531935548, "ARAVA": 0.4494934906891373, "ARIPIPRAZOLE": 0.1274153257237848, "ASPARAGINASE": 0.3048007616504066, "AUBAGIO": 0.3969796966834802, "AVANDAMET": 10.24163070631221, "AVANDIA": 10.338335514941262, "AVASTIN": 0.6200469848970246, "AXICABTAGENE": 1.938711927362232, "AZACITIDINE": 1.1131114595317444, "AZILECT": 2.075444499167431, 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1.5838430776670764, "TAMIFLU": 0.579050389044364, "TASIGNA": 3.4703343012533105, "TELMISARTAN": 0.5168263419425209, "TERIPARATIDE": 1.8462935894544892, "TESTOSTERONE": 2.0034923906712687, "THALIDOMIDE": 0.971832136108148, "TICAGRELOR": 0.674728902149579, "TIKOSYN": 24.6926801367687, "TORISEL": 0.5252259960741543, "TOUJEO": 0.7754269642451536, "TOVIAZ": 1.0131871688844265, "TOZINAMERAN": 0.8484551346834855, "TRACLEER": 1.5617092216070398, "TRELEGY": 3.1694182559585604, "TREMFYA": 0.6746726351716158, "TRULICITY": 0.97363326945665, "TRUVADA": 0.0204018771732167, "VALSARTAN": 2.9228201652126278, "VAXZEVRIA": 0.277122320832985, "VEKLURY": 1.4949973445596445, "VELTASSA": 1.3723115530974743, "VENCLYXTO": 0.9807573638142376, "VENETOCLAX": 1.4304624990173425, "VFEND": 0.5471587719355244, "VIAGRA": 1.934317093429684, "VICTOZA": 1.5159855537044735, "VIMPAT": 2.008976241982691, "VORICONAZOLE": 0.5706092998698657, "VOTRIENT": 0.6206095825522667, "XALKORI": 0.6725680420685334, "XARELTO": 4.146845533062671, "XELJANZ": 0.9519460428795063, "XOFIGO": 0.6405737658161285, "XOLAIR": 0.6944046119173676, "XTANDI": 1.078256176413401, "YERVOY": 0.8999260275250154, "YESCARTA": 1.43076683058666, "ZELBORAF": 1.227180620938548, "ZOMETA": 1.05688614807624, "ZOSTAVAX": 1.8667423592754544, "ZYPREXA": 0.6237162453374103, "null": 1.2129288106419935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11000.json
new file mode 100644
index 00000000000..90c99dafd3d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11000.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6378806866114158, "KEPPRA": 5.56143134609871, "SPIKEVAX": 0.6235548191854903, "TOZINAMERAN": 1.7089814034454138, "VAXZEVRIA": 0.8972931532741016, "XYREM": 44.54866766080696, "null": 1.6581570147355191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11001.json
new file mode 100644
index 00000000000..b7076b49c21
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11001.json
@@ -0,0 +1 @@
+{"BRIVARACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11002.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11002.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11003.json
new file mode 100644
index 00000000000..b0b01b22d1b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11003.json
@@ -0,0 +1 @@
+{"CHAMPIX": 4.565114610802602, "CYMBALTA": 6.699437925479039, "SPIKEVAX": 0.4024473843191514, "TAMIFLU": 11.817397149523682, "VAXZEVRIA": 0.4396210244575467, "VFEND": 19.60036207220623, "null": 1.785423189141818}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11004.json
new file mode 100644
index 00000000000..ff0c8e9dd1a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11004.json
@@ -0,0 +1 @@
+{"ABACAVIR": 2.150067382438213, "APIXABAN": 13.283675651103362, "ATRIPLA": 0.4049705343957539, "BIKTARVY": 10.599539352906818, "CHAMPIX": 3.455257523423543, "COMIRNATY": 0.1516691616027639, "CYMBALTA": 1.0342790364151906, "KAFTRIO": 16.41670604303656, "KEPPRA": 1.7660928408963252, "SPIKEVAX": 0.0921956122788839, "TAMIFLU": 25.045044537462992, "TOZINAMERAN": 0.7650780989943378, "VAXZEVRIA": 0.4111889256353798, "XYREM": 16.091386182075908, "null": 3.001927793142378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11005.json
new file mode 100644
index 00000000000..534125e58e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11005.json
@@ -0,0 +1 @@
+{"XYREM": 401.28825518090326, "null": 1.2374542849099122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11006.json
new file mode 100644
index 00000000000..8c555a96378
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11006.json
@@ -0,0 +1 @@
+{"null": 0.8914085045646701}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11007.json
new file mode 100644
index 00000000000..ea6e4f33be4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11007.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 1.4641709926363862, "COMIRNATY": 0.3589703862158283, "CYMBALTA": 2.00634259212635, "FENTANYL": 2.667539785489289, "GARDASIL": 1.8061548184654184, "IBUPROFEN": 3.294931053215848, "KEPPRA": 2.468217702397012, "OLANZAPINE": 2.8951029269823354, "SPIKEVAX": 0.2840090772443283, "VAXZEVRIA": 0.1219346745187628, "ZYPREXA": 4.107898254638778, "null": 2.9902552712718364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11008.json
new file mode 100644
index 00000000000..abcc75780d2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11008.json
@@ -0,0 +1 @@
+{"BENRALIZUMAB": 55.40107766821069, "CARIPRAZINE": 193.9394958766189, "COMIRNATY": 0.4695911910426864, "FYCOMPA": 33.280715340706934, "KEPPRA": 1.9496067218309407, "LANTUS": 1.1762061233505263, "OLANZAPINE": 3.9105703484378607, "PEGASYS": 1.2486232993264443, "SPIKEVAX": 0.3562142549163427, "SUTENT": 0.980204082149737, "TOZINAMERAN": 1.290382726044519, "VAXZEVRIA": 0.5912421765355298, "null": 1.3451772398363673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11009.json
new file mode 100644
index 00000000000..68c32d461ec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11009.json
@@ -0,0 +1 @@
+{"OMALIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1101.json
index e4b2652f84c..25873c8a119 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1101.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"APIXABAN": 1.1578353683844904, "AVANDAMET": 11.752151480888234, "AVANDIA": 13.00861855186044, "BLINDED": 132.11433638144547, "BUSULFAN": 7.234353765867994, "CHAMPIX": 0.8481134115912682, "CLOPIDOGREL": 0.9319578223907174, "COMBIVIR": 3.15522514227467, "COMIRNATY": 0.6134147911591724, "DARZALEX": 4.740390194507171, "DASATINIB": 14.029232324717643, "DEXAMETHASONE": 1.1468396548942614, "ELIQUIS": 3.941840467759678, "ENTRESTO": 3.9373078428742767, "ESBRIET": 1.866625039543285, "IBUPROFEN": 1.1491480539111243, "KEPPRA": 0.532390538703005, "LANTUS": 0.317581323448714, "LOPINAVIR": 11.8896622408151, "MULTAQ": 27.74035632452737, "OPDIVO": 1.3140978986309606, "OPSUMIT": 6.171882961567687, "PANTOPRAZOLE": 2.2856471186909584, "PLAVIX": 0.5725740950488912, "PRADAXA": 9.031644623877863, "REVATIO": 2.5521778269132214, "RITUXIMAB": 1.8050065963309592, "SPIKEVAX": 0.664689058253002, "TOZINAMERAN": 0.580588236135869, "TRACLEER": 5.94304999987833, "VAXZEVRIA": 0.3042356853691834, "VFEND": 1.5706946648013498, "VIAGRA": 1.6122863007452044, "VIMPAT": 3.4506883187713835, "ZOSTAVAX": 2.027640543499685, "ZYPREXA": 0.7830104500471607, "null": 1.151374231437716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11010.json
new file mode 100644
index 00000000000..d054b2e3a09
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11010.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.1544896591528806, "APIDRA": 1.8487552121422264, "BRINTELLIX": 1.8630852046331616, "CHAMPIX": 0.6673259638696205, "COMIRNATY": 0.6907214800882873, "CYMBALTA": 0.3742087935327042, "DULOXETINE": 4.874244183823887, "ELIQUIS": 0.522381303579446, "HUMALOG": 1.3990634609169033, "IBRANCE": 0.7605600638805112, "IBUPROFEN": 1.3950403332855217, "INLYTA": 2.5229841517033065, "INVEGA": 22.562687853543807, "KEPPRA": 2.420083405132322, "LANTUS": 3.8629929226574222, "OLANZAPINE": 2.867497600608852, "OPSUMIT": 2.12231928062709, "PEGASYS": 1.0910524242513306, "PEGINTRON": 0.98198107612484, "RINVOQ": 2.0297640777563317, "SHINGRIX": 1.0236491275264414, "SPIKEVAX": 1.186225931672881, "SUTENT": 2.243010609074584, "TOZINAMERAN": 0.931980272905459, "VAXZEVRIA": 0.6667773014094632, "VIMPAT": 4.189586734818063, "ZYPREXA": 2.448737819521622, "null": 1.3101687386174306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11011.json
new file mode 100644
index 00000000000..299a51c91d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11011.json
@@ -0,0 +1 @@
+{"null": 1.2894317472183354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11012.json
new file mode 100644
index 00000000000..3823b65b238
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11012.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.0990716799610374, "FIRDAPSE": 56.72582272075472, "GEFITINIB": 241.04846799687147, "HYCAMTIN": 105.22367541660442, "IRESSA": 17.97279345992964, "LANTUS": 1.763476003819526, "STELARA": 2.890424121213205, "TAGRISSO": 21.49811021775693, "TOPOTECAN": 69.52729451348233, "TRELEGY": 10.904478102673782, "null": 0.7066035182262799}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11013.json
new file mode 100644
index 00000000000..3567e569364
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11013.json
@@ -0,0 +1 @@
+{"null": 1.1414720922686423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11014.json
new file mode 100644
index 00000000000..3d6d5ffe077
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11014.json
@@ -0,0 +1 @@
+{"null": 0.3623380263389641}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11015.json
new file mode 100644
index 00000000000..6ceb0039616
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11015.json
@@ -0,0 +1 @@
+{"FIRDAPSE": 763.5603741761499}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11016.json
new file mode 100644
index 00000000000..081c0fa516f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11016.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.048901818978695, "GARDASIL": 8.297698284434189, "SPIKEVAX": 1.5792334684394436, "TELMISARTAN": 52.36215712988933, "TOZINAMERAN": 3.890663665054416, "VAXZEVRIA": 0.5829589273627396, "null": 0.2212445581519221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11017.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11017.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11018.json
new file mode 100644
index 00000000000..583ef5a16ac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11018.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 5.175580694411001, "CICLOSPORIN": 6.878767995172723, "CIMZIA": 3.017210040199233, "CYTARABINE": 3.360853853354893, "DEXMEDETOMIDINE": 76.56535589985788, "ENFUVIRTIDE": 210.3907542436804, "GARDASIL": 3.3728275618111363, "HUMALOG": 1.3915376519493383, "ISENTRESS": 51.689640172356704, "KALETRA": 7.863640013734836, "KEPPRA": 17.54336531313077, "LAMIVUDINE": 14.663332322560398, "LEVETIRACETAM": 8.806245491809387, "MISOPROSTOL": 279.07197100062405, "OLANZAPINE": 3.445632556819413, "SUBOXONE": 8.648944759472482, "null": 1.793124917277466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11019.json
new file mode 100644
index 00000000000..e10d94683c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11019.json
@@ -0,0 +1 @@
+{"AFINITOR": 3.531429407875461, "CLOPIDOGREL": 16.227932248224924, "COMIRNATY": 0.0435810058925149, "EFIENT": 46.33871289750287, "ELIQUIS": 12.940928082563918, "KEYTRUDA": 2.9413889644352835, "LIXIANA": 22.434968652812653, "NEXAVAR": 5.025707128924461, "PLAVIX": 11.539631728331493, "VAXZEVRIA": 0.2633850782611941, "null": 1.111052363257614}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1102.json
index 283ba485960..6be5580992a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1102.json
@@ -1 +1 @@
-{"null": 3.5759889551906507}
\ No newline at end of file
+{"null": 2.5976518060301648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11020.json
new file mode 100644
index 00000000000..a3bfc9f841c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11020.json
@@ -0,0 +1 @@
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11021.json
new file mode 100644
index 00000000000..f22318df47c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11021.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.5048489845845888, "AFINITOR": 1.989301342446368, "AIMOVIG": 2.363007667176414, "APIXABAN": 4.705964938045093, "AVASTIN": 3.105634841817754, "BEVACIZUMAB": 5.273115756705415, "BRAFTOVI": 4.056177116693562, "BYETTA": 2.865651068245033, "CELLCEPT": 3.894511014543463, "CIMZIA": 5.138707548865349, "COMIRNATY": 0.0426720991730852, "CYTARABINE": 3.0910296837717315, "ELIQUIS": 0.9148409233221888, "ENTYVIO": 6.421678803115421, "EXJADE": 1.6581484881241295, "FASLODEX": 2.0936996016950724, "HUMIRA": 3.575171539071658, "IBRANCE": 1.3689800369223315, "IRINOTECAN": 8.470801694405056, "JANUMET": 4.288216026052518, "KEYTRUDA": 1.689393736910668, "LONSURF": 13.558433677410653, "LYRICA": 2.51367092477118, "OPSUMIT": 1.6855995874739034, "PEGASYS": 0.7762241368899974, "RITUXIMAB": 2.879130778259264, "ROTATEQ": 3.438239630486306, "RUBRACA": 27.70613270006536, "SAXENDA": 2.6217734919539297, "SPIKEVAX": 0.0697389191876074, "STELARA": 6.0513285303738105, "SUTENT": 0.5293667199074632, "TRULICITY": 4.960041638552545, "VICTOZA": 2.7851929746143083, "ZOSTAVAX": 0.8504447002990471, "null": 1.4465384434658497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11022.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11022.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11023.json
new file mode 100644
index 00000000000..fcbd1291f11
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11023.json
@@ -0,0 +1 @@
+{"ALIMTA": 13.07884455767921, "AVASTIN": 44.03232481266284, "BEVACIZUMAB": 11.571499059519912, "CABOMETYX": 18.603948372029556, "KEYTRUDA": 20.73023046514844, "LENVIMA": 26.649858926258048, "ROACTEMRA": 7.817520158408565, "STELARA": 3.65892771296618, "STIVARGA": 13.151896442518924, "SUTENT": 2.028037825982242, "null": 0.7267742127288431}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11024.json
new file mode 100644
index 00000000000..8c19c969615
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11024.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 47.64967782709621, "STELARA": 16.305133037625076, "null": 0.7486744463547504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11025.json
new file mode 100644
index 00000000000..560559785b8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11025.json
@@ -0,0 +1 @@
+{"STELARA": 34.48916578157253, "null": 0.5020245583541936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11026.json
new file mode 100644
index 00000000000..516b6832eed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11026.json
@@ -0,0 +1 @@
+{"null": 0.6847617004742252}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11027.json
new file mode 100644
index 00000000000..fde149da70b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11027.json
@@ -0,0 +1 @@
+{"STELARA": 4.789336786232356, "null": 3.055474937208127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11028.json
new file mode 100644
index 00000000000..dbb2f079020
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11028.json
@@ -0,0 +1 @@
+{"null": 0.4076611556508092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11029.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11029.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1103.json
index 2ba2eb7dcc1..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1103.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 20.72789796737924, "CLOPIDOGREL": 16.92456982373375, "OLANZAPINE": 9.231411979906357, "null": 1.379094401996441}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11030.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11030.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11031.json
new file mode 100644
index 00000000000..1d998a5ce2f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11031.json
@@ -0,0 +1 @@
+{"AFINITOR": 113.70893985344784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11032.json
new file mode 100644
index 00000000000..b28cc5c4981
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11032.json
@@ -0,0 +1 @@
+{"null": 1.0697945780850726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11033.json
new file mode 100644
index 00000000000..55c409669be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11033.json
@@ -0,0 +1 @@
+{"STELARA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11034.json
new file mode 100644
index 00000000000..7bcf4fcaffa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11034.json
@@ -0,0 +1 @@
+{"null": 1.840781507434695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11035.json
new file mode 100644
index 00000000000..4de0aba521a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11035.json
@@ -0,0 +1 @@
+{"BOSENTAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11036.json
new file mode 100644
index 00000000000..30380b6ee3a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11036.json
@@ -0,0 +1 @@
+{"null": 1.719128601799418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11037.json
new file mode 100644
index 00000000000..e25d39def16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11037.json
@@ -0,0 +1 @@
+{"ANAKINRA": 71.26830444200453, "COMIRNATY": 0.1391840911148794, "GARDASIL": 96.01306276343556, "null": 0.6776605754656471}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11038.json
new file mode 100644
index 00000000000..1dc2ca72ef7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11038.json
@@ -0,0 +1 @@
+{"GARDASIL": 294.7495062299504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11039.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11039.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1104.json
index f12b495e7fa..db7aae691de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1104.json
@@ -1 +1 @@
-{"COVID19": 13.840275549514487}
\ No newline at end of file
+{"null": 1.358446126336236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11040.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11040.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11041.json
new file mode 100644
index 00000000000..b7f1631806a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11041.json
@@ -0,0 +1 @@
+{"OMALIZUMAB": 158.69988935407588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11042.json
new file mode 100644
index 00000000000..d783b54f541
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11042.json
@@ -0,0 +1 @@
+{"null": 1.808241299225486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11043.json
new file mode 100644
index 00000000000..f75dd1a6a69
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11043.json
@@ -0,0 +1 @@
+{"CAELYX": 191.984106825042, "CICLOSPORIN": 137.82891756072598, "MYCOPHENOLATE": 116.2992879854938}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11044.json
new file mode 100644
index 00000000000..7c474540fe2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11044.json
@@ -0,0 +1 @@
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11045.json
new file mode 100644
index 00000000000..6765b2090fa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11045.json
@@ -0,0 +1 @@
+{"AIMOVIG": 0.5053867499413396, "APIXABAN": 0.6399744371615567, "ARAVA": 0.7511882879990909, "AVAMYS": 6.809258122185249, "BENLYSTA": 2.040137068363641, "BUDESONIDE": 11.882511313996368, "BUPRENORPHINE": 1.4810980294396268, "BYDUREON": 1.2639892627090157, "CAPECITABINE": 1.3481454740517809, "CICLOSPORIN": 0.2886826795299271, "COMIRNATY": 1.069932865647247, "COSENTYX": 1.1644577478422893, "CYMBALTA": 0.3150962665385635, "DARZALEX": 2.0162897187700253, "ELIQUIS": 0.233354833421668, "ENTRESTO": 0.6492309901705127, "ENTYVIO": 0.5685863731446139, "ESBRIET": 0.9847467443558106, "EXFORGE": 1.3976926200913014, "FASENRA": 1.450491034880368, "FLUTICASONE": 26.78261297547725, "FORXIGA": 0.5925299711196453, "GARDASIL": 0.4164246224686297, "GREPID": 37.0227655022944, "HUMALOG": 0.2797206349454698, "IBRANCE": 0.7422634684205701, "KEPPRA": 0.2001208907337534, "KEYTRUDA": 0.3715546779874089, "LEVOFLOXACIN": 0.4562015587354649, "MEPOLIZUMAB": 2.7925246354354805, "MMRVAXPRO": 0.5309239766113405, "MODERNA": 0.379002841813843, "NUCALA": 16.02054114837622, "OCRELIZUMAB": 1.961876484689865, "OMALIZUMAB": 2.275884020133656, "OPSUMIT": 0.3520622823890515, "OZEMPIC": 11.600746116193337, "RELVAR": 2.5883406083312512, "REVATIO": 1.2302624250052925, "SIMPONI": 0.2783721828478355, "SPIKEVAX": 0.830861194552401, "STELARA": 0.2215932523244635, "SUBOXONE": 3.5516594507302908, "SUTENT": 0.1834378608882178, "SYNAGIS": 1.8408666052120168, "TOZINAMERAN": 2.4120233289624067, "TRELEGY": 0.7449292598408767, "VAXZEVRIA": 0.9595757613429456, "XELJANZ": 0.5815589566520736, "XOLAIR": 4.156687875883475, "XTANDI": 0.5107257754756961, "ZOSTAVAX": 0.419637402022249, "null": 1.3911770111334074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11046.json
new file mode 100644
index 00000000000..92a87f2a99c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11046.json
@@ -0,0 +1 @@
+{"AIMOVIG": 2.2722930784614226, "APIXABAN": 2.147594334252728, "BENRALIZUMAB": 44.10888192705847, "CHAMPIX": 2.2131542156405373, "COMIRNATY": 0.1773979321823555, "CYMBALTA": 3.437164585659436, "DUAKLIR": 360.10651294337424, "FENTANYL": 5.774016831290838, "HUMALOG": 7.8903065307983935, "MEPOLIZUMAB": 8.734594978338489, "OLANZAPINE": 2.157422864159865, "PREGABALIN": 28.17506337364058, "SOMATROPIN": 88.88864192627597, "SPIKEVAX": 0.2327521518381983, "TOZINAMERAN": 0.222261882827297, "TRELEGY": 4.024942111467695, "XYREM": 19.3089756108348, "ZOSTAVAX": 3.689987663239264, "null": 1.812248572411548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11047.json
new file mode 100644
index 00000000000..4f12e468ed5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11047.json
@@ -0,0 +1 @@
+{"null": 4.860737640768128}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11048.json
new file mode 100644
index 00000000000..15aca6ff7c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11048.json
@@ -0,0 +1 @@
+{"ABILIFY": 8.340877861119433, "ARIPIPRAZOLE": 48.8681090785081, "BUPRENORPHINE": 15.264361218347547, "COMIRNATY": 0.1255760031581839, "CYMBALTA": 3.0314239032146166, "SUBOXONE": 7.535229397030182, "null": 1.81019557324551}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11049.json
new file mode 100644
index 00000000000..9006656f847
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11049.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.441650356392475, "ABILIFY": 15.41781469781076, "ANTIBIOTICS": 29.35255761224113, "ARIPIPRAZOLE": 9.202454741665868, "ATRIPLA": 0.2396258898631388, "AVAMYS": 3.2149051771407864, "BRINTELLIX": 3.576036908366408, "CHAMPIX": 14.43004080484692, "COMIRNATY": 0.070007527726809, "CYMBALTA": 2.9069268938474484, "FENTANYL": 1.9846694984283235, "GARDASIL": 4.90207343166977, "KEPPRA": 3.246895487756791, "LATUDA": 6.315277835281716, "LEVETIRACETAM": 2.878733973638248, "LYRICA": 2.2281588643902586, "OLANZAPINE": 5.602445324083959, "SPIKEVAX": 0.0919587802762745, "VAXZEVRIA": 0.058247958122671, "ZYPREXA": 4.470849860454311, "null": 2.943977501292406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1105.json
index 67c472877b3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1105.json
@@ -1 +1 @@
-{"JARDIANCE": 90.66832647287978}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11050.json
new file mode 100644
index 00000000000..f128038911a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11050.json
@@ -0,0 +1 @@
+{"ABILIFY": 47.87742560728553, "null": 1.3872398812792184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11051.json
new file mode 100644
index 00000000000..0386a5e09fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11051.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 5.156943528712034, "BELIMUMAB": 85.62767969823344, "BENLYSTA": 28.13200456572907, "COMIRNATY": 0.1251274339563071, "ELIQUIS": 0.9205929494745376, "MEPOLIZUMAB": 15.01936565344599, "NUCALA": 17.17012493855582, "PLAVIX": 5.500402765978257, "SHINGRIX": 2.666005857915874, "null": 4.690096074006906}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11052.json
new file mode 100644
index 00000000000..35c05d41dae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11052.json
@@ -0,0 +1 @@
+{"null": 1.0694489479752738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11053.json
new file mode 100644
index 00000000000..c5ffeb653ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11053.json
@@ -0,0 +1 @@
+{"ARAVA": 8.01678529751211, "COMIRNATY": 0.2957890915418757, "OPTIMARK": 19.112653642371285, "null": 0.7560257983344976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11054.json
new file mode 100644
index 00000000000..b5fffaf4307
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11054.json
@@ -0,0 +1 @@
+{"ENTYVIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11055.json
new file mode 100644
index 00000000000..2c121b8a701
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11055.json
@@ -0,0 +1 @@
+{"ELIQUIS": 7.842699270158175, "null": 1.3887096457828312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11056.json
new file mode 100644
index 00000000000..3cd95e072ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11056.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 8.454190368499198, "COMIRNATY": 0.1637253833040453, "ROACTEMRA": 18.61854210485971, "null": 0.8023855957998979}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11057.json
new file mode 100644
index 00000000000..9d5be653541
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11057.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4702262489570145, "null": 0.7397947373347633}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11058.json
new file mode 100644
index 00000000000..27453adbaae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11058.json
@@ -0,0 +1 @@
+{"AIMOVIG": 115.20590562230402, "JANUVIA": 23.419770355256897, "null": 0.9150816467450968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11059.json
new file mode 100644
index 00000000000..e6f8d0145d0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11059.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2709232852221515, "null": 0.50994444476377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1106.json
index 909cef3991f..043eac70451 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1106.json
@@ -1 +1 @@
-{"HYDROCORTISONE": 14.501248754679011, "IBUPROFEN": 8.48137088452831, "INSULIN": 4.48388198417262, "JARDIANCE": 3.207776266907315, "LACOSAMIDE": 52.59603691086101, "LEVETIRACETAM": 92.12923947398713, "MIDAZOLAM": 11.784678206314409, "null": 1.9048774478458768}
\ No newline at end of file
+{"ASPARAGINASE": 5.094021886965418, "ATRIPLA": 0.2907933709937034, "BUDESONIDE": 0.7624891764798716, "BUPRENORPHINE": 1.0360997139105428, "COMBIVIR": 10.796677835076316, "COMIRNATY": 0.0450176085745049, "CYMBALTA": 0.6208261584783441, "EMTRICITABINE": 20.260540210180885, "EPIVIR": 7.336026015714461, "FENTANYL": 0.7407492743541353, "GARDASIL": 0.4115240135583118, "HUMALOG": 0.8029735023094448, "IBUPROFEN": 3.859485214972025, "KALETRA": 3.097888882328736, "KEPPRA": 4.035017599409113, "LANTUS": 0.2832835664811886, "LEVETIRACETAM": 3.719095114159988, "LYRICA": 1.1337080209781731, "MEPOLIZUMAB": 2.809111659497616, "MYCOPHENOLATE": 2.9144085509852693, "OPSUMIT": 1.3460762968386124, "PEGASYS": 0.3400865272200669, "SOVALDI": 6.304609474381127, "SPIKEVAX": 0.0627099523796376, "SYNAGIS": 2.501706363876992, "TRACTOCILE": 85.01316955297854, "ZYPREXA": 1.3435238083081176, "null": 6.289934042401798}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11060.json
new file mode 100644
index 00000000000..dce965f9c2d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11060.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": 10.931447528419207, "null": 2.294501949835704}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11061.json
new file mode 100644
index 00000000000..995bd579a3f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11061.json
@@ -0,0 +1 @@
+{"MEKINIST": 58.389183700585455, "PAZOPANIB": 266.8290850373411, "SUTENT": 1.9798213675365608, "VOTRIENT": 317.1814984074679, "null": 0.611573580022985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11062.json
new file mode 100644
index 00000000000..ac1cae3a435
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11062.json
@@ -0,0 +1 @@
+{"ARAVA": 5.492574302228622, "COMIRNATY": 2.049226285732467, "METHOTREXATE": 12.652001671199791, "SPIKEVAX": 0.2492974481050534, "VAXZEVRIA": 0.2680824004237562, "null": 0.4996323098849438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11063.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11063.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11064.json
new file mode 100644
index 00000000000..7deaffa0290
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11064.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6079374634822581, "COTELLIC": 156.49582911159865, "ESBRIET": 35.12500578326797, "OLYSIO": 83.46544440553645, "null": 0.6753137495678722}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11065.json
new file mode 100644
index 00000000000..f9f801da6c7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11065.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2380547759820756, "null": 0.6391116412240577}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11066.json
new file mode 100644
index 00000000000..c1f0f3fda22
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11066.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7492191876773767, "null": 0.8132120548405579}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11067.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11067.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11068.json
new file mode 100644
index 00000000000..b6d7edb8135
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11068.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.122080082511328, "LATUDA": 22.695998013031364, "ZYPREXA": 7.375252268434184, "null": 2.307652101764861}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11069.json
new file mode 100644
index 00000000000..7235cffca44
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11069.json
@@ -0,0 +1 @@
+{"ZYPREXA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1107.json
index e97a1217f1a..01a37a10f9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1107.json
@@ -1 +1 @@
-{"IBUPROFEN": 53.68429781821969, "null": 1.0512200080054794}
\ No newline at end of file
+{"OPSUMIT": 75.07100072061395, "TRACLEER": 144.42100034513936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11070.json
new file mode 100644
index 00000000000..4f7cb8d6fae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11070.json
@@ -0,0 +1 @@
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11071.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11071.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11072.json
new file mode 100644
index 00000000000..71cec46b844
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11072.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 79.88390378582609, "null": 1.9659990130617704}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11073.json
new file mode 100644
index 00000000000..52a048839a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11073.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.435041271324074, "null": 0.5447738916505026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11074.json
new file mode 100644
index 00000000000..c63081b2860
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11074.json
@@ -0,0 +1 @@
+{"null": 1.4031695771790973}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11075.json
new file mode 100644
index 00000000000..6e2df068520
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11075.json
@@ -0,0 +1 @@
+{"ABILIFY": 18.36497837226428, "ARIPIPRAZOLE": 9.345747886914287, "COMIRNATY": 1.099519976790884, "COSENTYX": 2.21568209299251, "CYMBALTA": 3.078883349683028, "FENTANYL": 4.017871061175736, "GARDASIL": 15.360080516056057, "OLANZAPINE": 2.747834790323098, "SPIKEVAX": 0.3402836791828921, "TWINRIX": 10.998725969201692, "VAXZEVRIA": 0.1654788877068156, "ZYPREXA": 1.668168994538399, "null": 1.034743811595196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11076.json
new file mode 100644
index 00000000000..fb5a17f0407
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11076.json
@@ -0,0 +1 @@
+{"null": 1.1637784968729086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11077.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11077.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11078.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11078.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11079.json
new file mode 100644
index 00000000000..2e5049b4b28
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11079.json
@@ -0,0 +1 @@
+{"BRINTELLIX": 3.294857358142008, "BUPRENORPHINE": 35.8762778588666, "CHAMPIX": 9.140703014946228, "COMIRNATY": 0.0974911288924753, "CYMBALTA": 2.928451300136537, "KEPPRA": 1.8447018726148707, "LATUDA": 5.197930357832098, "LYRICA": 3.384883499093425, "OLANZAPINE": 5.75692459268468, "SPIKEVAX": 0.093910013517105, "TAMIFLU": 7.370116070983693, "VAXZEVRIA": 0.0461788760679363, "XYREM": 52.219381996692576, "ZYPREXA": 2.535021429605959, "null": 2.91396349587976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1108.json
index e457e38a867..450b4fd133c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1108.json
@@ -1 +1 @@
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\ No newline at end of file
+{"null": 1.4631329108364377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11080.json
new file mode 100644
index 00000000000..9f54dfa04ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11080.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11081.json
new file mode 100644
index 00000000000..0942064c912
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11081.json
@@ -0,0 +1 @@
+{"ZYPREXA": 13.438557631669282, "null": 5.156151674866948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11082.json
new file mode 100644
index 00000000000..fa1c81ddfe0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11082.json
@@ -0,0 +1 @@
+{"ABILIFY": 4.069804954999277, "ACTRAPID": 7.838605003762248, "APIDRA": 16.182754782088264, "ARIPIPRAZOLE": 1.095937878444402, "BRINTELLIX": 1.979190598858953, "COMIRNATY": 0.0594178592602652, "CYMBALTA": 2.045247920330149, "HUMALOG": 7.000102423407814, "IBUPROFEN": 4.6657706130528735, "INSULIN": 1.4964970018777173, "INVEGA": 21.06219722126083, "KEPPRA": 4.537925042165941, "LANTUS": 3.5174702370828723, "LEVEMIR": 2.266835462716338, "LEVETIRACETAM": 2.609389755601128, "LEVOFLOXACIN": 0.6581025779299778, "LYRICA": 5.673017458807636, "MMRVAXPRO": 0.7723806100007766, "NOVONORM": 32.19721331352718, "OLANZAPINE": 6.380581134936578, "REPAGLINIDE": 44.78243475853676, "SPIKEVAX": 0.0477925785446095, "SYCREST": 12.741456486049302, "VAXZEVRIA": 0.0165772496923619, "ZYPADHERA": 9.28064573873982, "ZYPREXA": 5.251701376504839, "null": 4.907313444994574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11083.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11083.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11084.json
new file mode 100644
index 00000000000..e16b2b7f95f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11084.json
@@ -0,0 +1 @@
+{"BUSULFAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11085.json
new file mode 100644
index 00000000000..de866ac7ed0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11085.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 83.13224177148385, "OLANZAPINE": 62.14673550028079, "null": 1.2215189190885534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11086.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11086.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11087.json
new file mode 100644
index 00000000000..319014fc1d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11087.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.874908062287426, "SPIKEVAX": 2.004243445077013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11088.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11088.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11089.json
new file mode 100644
index 00000000000..6106b40dc6a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11089.json
@@ -0,0 +1 @@
+{"null": 3.7846578968294087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1109.json
index b3699e3f14b..ac02686c049 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1109.json
@@ -1 +1 @@
-{"ABATACEPT": 21.417666916848027, "ADALIMUMAB": 29.745151528815597, "APREMILAST": 77.84293364138503, "ARAVA": 7.5213671382287615, "CICLOSPORIN": 5.311412088344321, "ENBREL": 74.07229167258488, "FORSTEO": 11.281123712948332, "MIMPARA": 68.61286924326238}
\ No newline at end of file
+{"APIXABAN": 186.64203289585464, "AVANDIA": 1.8993627097841237, "CLOPIDOGREL": 1.3873327668506237, "COMIRNATY": 0.3219933546736265, "ELIQUIS": 1.1711473929183231, "OPSUMIT": 2.246824754712711, "SPIKEVAX": 0.1794677588163169, "TOZINAMERAN": 0.2941193709181239, "VAXZEVRIA": 0.0662508815051673, "null": 1.036549890686996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11090.json
new file mode 100644
index 00000000000..f0401afe8dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11090.json
@@ -0,0 +1 @@
+{"null": 0.5234282361212452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11091.json
new file mode 100644
index 00000000000..d4b715f5380
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11091.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.9691132996132, "AFINITOR": 0.447562349629711, "AIMOVIG": 0.4785973553083006, "ANORO": 0.913737905712096, "APIDRA": 1.3235932072135654, "APIXABAN": 0.2491130508019347, "ARANESP": 0.1671650774917723, "ARAVA": 0.0314457906890606, "ARIPIPRAZOLE": 1.4969645294638574, "ASPARAGINASE": 0.638737122282615, "ATRIPLA": 0.04508993116296, "AUBAGIO": 2.288304495519616, "AVANDIA": 0.7436264460612088, "AVASTIN": 0.7937373333615804, "AZATHIOPRINE": 0.3105753008370398, "BENLYSTA": 1.18555802479066, "BETAFERON": 0.8868525304272314, "BEVACIZUMAB": 0.8238754428702548, "BIKTARVY": 0.3837489317109251, "BOSULIF": 1.2399750524220097, "BRAFTOVI": 1.9517234572824744, "BRILIQUE": 0.5018595813535909, "BRINTELLIX": 0.7219540863715116, "BRIVARACETAM": 2.9433795418342923, "BUDESONIDE": 0.4094151401582445, "BUMETANIDE": 4.223316646849057, "BUPIVACAINE": 1.495052352584985, "BUPRENORPHINE": 0.751510053541923, "BYDUREON": 0.43225423968721, "CABOMETYX": 0.4167664215790495, "CAPECITABINE": 0.6288844853555746, 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0.3255431690492307, "FENTANYL": 0.9366388800264196, "FIRDAPSE": 3.0044186285394074, "FORSTEO": 0.6269236137497128, "FORXIGA": 0.2307522662538561, "FYCOMPA": 1.2355713557536498, "GARDASIL": 1.4645469823237436, "GLIBENCLAMIDE": 2.7727315351549358, "HIZENTRA": 0.4837595169636006, "HUMALOG": 1.7034998812726725, "HUMIRA": 0.204536718982451, "HYDROCORTISONE": 0.6715115520271389, "IBRANCE": 1.21063912629352, "IBUPROFEN": 0.6273446302245994, "INFANRIX": 1.0706670161649616, "INLYTA": 1.61408146078662, "INSULIN": 0.6283089083458416, "INVANZ": 7.385535311030932, "IRESSA": 0.7695295924307394, "IRINOTECAN": 1.2949701800684443, "JAKAVI": 0.3620895860082347, "JANUMET": 0.4343597831871672, "JANUVIA": 0.4868986333101406, "JARDIANCE": 0.6078470231047495, "KALETRA": 0.4918656789908674, "KEPPRA": 3.4652469833047768, "KESIMPTA": 1.3090656862406769, "KEYTRUDA": 0.5047758592601246, "KYMRIAH": 0.7877438497493595, "LACOSAMIDE": 1.3810300953818733, "LANTUS": 2.1144981436221566, "LATUDA": 2.904407322262264, 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0.5936997134330662, "RILUTEK": 8.068271285287935, "RINVOQ": 0.4272511220628137, "ROACTEMRA": 0.23429355867023, "SHINGRIX": 0.911009221175478, "SIFROL": 1.500748577226435, "SIMPONI": 0.22859016204804, "SOLIRIS": 0.5093327230539443, "SPIKEVAX": 0.3832304533367067, "SPRYCEL": 0.2746357076802903, "STALEVO": 4.318665600082211, "STELARA": 0.2581913740435873, "STIVARGA": 0.4517074242389703, "SUBOXONE": 0.86836504654542, "SUTENT": 1.0608063637777094, "TAGRISSO": 0.4137519171813759, "TAMIFLU": 2.358247846560329, "TASIGNA": 0.7868306308353482, "TELMISARTAN": 1.3717601853624326, "TOUJEO": 0.6772630161199484, "TOVIAZ": 2.191302984058232, "TOZINAMERAN": 1.2962954731375564, "TRELEGY": 0.5773451843690337, "TRULICITY": 0.2980424454546722, "TRUVADA": 0.0634707867259851, "TWINRIX": 1.0569213528141774, "VAXZEVRIA": 0.3161697679622075, "VFEND": 2.146992894476139, "VIAGRA": 1.4547435514019744, "VIMPAT": 1.6925280447404591, "VORICONAZOLE": 1.1142994818058125, "VOTRIENT": 0.6594177604491794, "XELJANZ": 1.124494942327942, "XOLAIR": 0.7463926570368312, "XTANDI": 0.9313141395046604, "XYREM": 0.9002142171007189, "YESCARTA": 0.9566183310315318, "ZOSTAVAX": 0.1909315075214963, "ZYPADHERA": 11.555275411917076, "ZYPREXA": 2.3416074504669715, "null": 2.072763060748855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11092.json
new file mode 100644
index 00000000000..f6a01982177
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11092.json
@@ -0,0 +1 @@
+{"ARAVA": 0.4245941346911654, "COMBIVIR": 6.2945091065344405, "EPIVIR": 12.35470784800599, "INFANRIX": 32.63828990591097, "KEPPRA": 2.3773087252372984, "MMRVAXPRO": 5.725840820502728, "PREVENAR": 20.675862585465403, "SUBOXONE": 6.974792737623972, "VAXZEVRIA": 0.0480273184641951, "null": 7.484411040062057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11093.json
new file mode 100644
index 00000000000..9d6f4433d84
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11093.json
@@ -0,0 +1 @@
+{"null": 3.8970617052242154}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11094.json
new file mode 100644
index 00000000000..c440f5cc6e7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11094.json
@@ -0,0 +1 @@
+{"null": 3.51233967253537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11095.json
new file mode 100644
index 00000000000..d79989b1e35
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11095.json
@@ -0,0 +1 @@
+{"null": 4.940954480673981}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11096.json
new file mode 100644
index 00000000000..e90cb3f68f7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11096.json
@@ -0,0 +1 @@
+{"null": 3.788888232385263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11097.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11097.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11098.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11098.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11099.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11099.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/111.json
index c57232a4ba2..92181b0d35a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/111.json
@@ -1 +1 @@
-{"null": 1.0073536249268118}
\ No newline at end of file
+{"BUPRENORPHINE": 17.392392260974194, "CHAMPIX": 0.8604512877779863, "CYMBALTA": 0.7449361030369206, "IBUPROFEN": 2.037489263820788, "INVOKANA": 16.224040042189866, "KEPPRA": 2.6669369548944286, "OLANZAPINE": 5.822704875884167, "SUBOXONE": 51.655873590722585, "VIAGRA": 4.213169256520356, "ZYPREXA": 1.9744171229992933, "null": 5.133496268433132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1110.json
index c041a5d9399..cfb19e56417 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1110.json
@@ -1 +1 @@
-{"ARANESP": 8.433325458690241, "BONVIVA": 18.091390498298043, "CINACALCET": 103.91006500180652, "EVENITY": 36.13298525304862, "FORSTEO": 24.425864054447946, "MICARDIS": 16.67973220125753, "MIMPARA": 881.6131772894765, "PROLIA": 80.47040917665356, "TRUVADA": 1.2160694582387357, "null": 1.5465043377606948}
\ No newline at end of file
+{"APIXABAN": 10.73508685148432, "BUSULFAN": 7.884580086702468, "CLOPIDOGREL": 3.0745461655385844, "COMIRNATY": 0.1269356460241277, "ELIQUIS": 74.38594594517983, "LIXIANA": 51.04701895647843, "MISOPROSTOL": 220.9642656207368, "NOVOSEVEN": 54.12663883398388, "VAXZEVRIA": 0.1556305989212278, "null": 0.5963838171667972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11100.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11100.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11101.json
new file mode 100644
index 00000000000..2148e63f658
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11101.json
@@ -0,0 +1 @@
+{"null": 2.058334869644988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11102.json
new file mode 100644
index 00000000000..4f8578d09f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11102.json
@@ -0,0 +1 @@
+{"null": 3.6304504933639694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11103.json
new file mode 100644
index 00000000000..6a5fe7ba61a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11103.json
@@ -0,0 +1 @@
+{"null": 3.250977480990757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11104.json
new file mode 100644
index 00000000000..fa63acb3950
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11104.json
@@ -0,0 +1 @@
+{"null": 1.3183814393892817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11105.json
new file mode 100644
index 00000000000..64e33cf124e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11105.json
@@ -0,0 +1 @@
+{"null": 3.05608141347548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11106.json
new file mode 100644
index 00000000000..6dede4261ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11106.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11107.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11107.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11108.json
new file mode 100644
index 00000000000..51ce01c9af8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11108.json
@@ -0,0 +1 @@
+{"null": 1.145626223782917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11109.json
new file mode 100644
index 00000000000..6b3806db1ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11109.json
@@ -0,0 +1 @@
+{"null": 4.5687160477034725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1111.json
index b34927d8ab6..8895daacfc9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1111.json
@@ -1 +1 @@
-{"null": 1.008089787236376}
\ No newline at end of file
+{"ALISKIREN": 4.497343274366538, "ARANESP": 0.8329874011575217, "AVANDAMET": 4.80374648200177, "AVANDIA": 6.017028078682692, "BRIDION": 3.5515985677646245, "BRILIQUE": 8.096380482297263, "CLOPIDOGREL": 1.1734768427979485, "COAPROVEL": 3.568299145361176, "COMIRNATY": 0.1651109547794711, "CORTICOSTEROIDS": 26.20967723560282, "DEXAMETHASONE": 0.5958026330369873, "EBIXA": 11.995956631558204, "ELIQUIS": 0.9874839642606812, "ENTRESTO": 2.6746104957443557, "EXELON": 14.675575961666516, "EXFORGE": 1.218283590386031, "FENTANYL": 1.7663088425479054, "FORSTEO": 0.552882364322394, "FORXIGA": 1.0153717991731026, "HUMALOG": 0.9793463942819632, "JANUMET": 1.22862371061375, "JARDIANCE": 1.2812705725073343, "KALETRA": 2.5326543317386254, "KEPPRA": 1.2371745473545297, "KEYTRUDA": 0.6372273886396143, "LACOSAMIDE": 5.693912997976467, "LANTUS": 0.556810525147412, "LEVEMIR": 1.906288694215838, "LEVETIRACETAM": 0.9831741589096226, "LEVOFLOXACIN": 0.5570165760078681, "MIDAZOLAM": 4.919193338103243, "OLANZAPINE": 0.6036009162787704, "PEGASYS": 0.8064403449870567, "PLAVIX": 1.106110942502519, "PROPRANOLOL": 5.151093636545982, "RAPISCAN": 57.79364215928979, "RASILEZ": 3.3427948123194016, "SPIKEVAX": 0.1989484830040402, "SUFENTANIL": 7.754753396190877, "SUTENT": 0.1724158974137903, "TASIGNA": 1.4111051346511256, "TICAGRELOR": 5.77635850162484, "TOZINAMERAN": 0.3219482349051359, "TRELEGY": 2.5443485024857275, "TRULICITY": 1.4534477030532194, "VAXZEVRIA": 0.1039131276321962, "VFEND": 1.560483443938881, "VIAGRA": 1.692946947803659, "VIMPAT": 17.732712575178837, "VOTRIENT": 0.7435124787144399, "ZOSTAVAX": 0.6002660198093916, "ZYPREXA": 0.6844299377748181, "null": 3.119836178783665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11110.json
new file mode 100644
index 00000000000..a96a50dd56c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11110.json
@@ -0,0 +1 @@
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11111.json
new file mode 100644
index 00000000000..2934224a3b5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11111.json
@@ -0,0 +1 @@
+{"null": 0.4583349584109148}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11112.json
new file mode 100644
index 00000000000..63f9182bd32
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11112.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.1506322600845285, "SPIKEVAX": 0.691288031108132, "VAXZEVRIA": 1.6276196898615922, "null": 0.5460972311692599}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11113.json
new file mode 100644
index 00000000000..441b3038213
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11113.json
@@ -0,0 +1 @@
+{"COMBIVIR": 28.548484528546588, "DARUNAVIR": 34.209163900383466, "DEXAMETHASONE": 2.5822555299887577, "KEPPRA": 4.085168496615326, "LEVETIRACETAM": 8.011296812519875, "null": 9.301229090347642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11114.json
new file mode 100644
index 00000000000..c7730dbfebf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11114.json
@@ -0,0 +1 @@
+{"null": 6.841423405340247}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11115.json
new file mode 100644
index 00000000000..8078677d5e3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11115.json
@@ -0,0 +1 @@
+{"null": 2.07410961515956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11116.json
new file mode 100644
index 00000000000..f437947a28f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11116.json
@@ -0,0 +1 @@
+{"null": 3.0368512204162816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11117.json
new file mode 100644
index 00000000000..183e0610075
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11117.json
@@ -0,0 +1 @@
+{"ARAVA": 1.7122476949369414, "ATRIPLA": 5.471946964134474, "FORSTEO": 6.148992879148731, "HUMALOG": 3.4576301741854403, "LYRICA": 6.658362866991502, "SUTENT": 1.2366095799774366, "TRUVADA": 1.6794610440505455, "XELJANZ": 2.16791202502268, "null": 1.1072883793021715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11118.json
new file mode 100644
index 00000000000..9ffcd954d2f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11118.json
@@ -0,0 +1 @@
+{"ABRAXANE": 11.192615021638726, "AFINITOR": 2.3633560930490107, "ARAVA": 0.9098072634319132, "ATRIPLA": 7.208791220765313, "AZATHIOPRINE": 2.9032002412249613, "BONVIVA": 11.53334467187501, "BUDESONIDE": 0.85151007957954, "BUPIVACAINE": 17.5772029753566, "CELLCEPT": 1.0367597662225017, "CICLOSPORIN": 1.2829677625074258, "CIMZIA": 0.4246977871187778, "COMIRNATY": 0.0286740325695455, "DEXAMETHASONE": 1.904756048375309, "ELIQUIS": 1.303868814807827, "ENZALUTAMIDE": 11.122643435363273, "EVENITY": 98.82642522688928, "EVISTA": 24.277002145931487, "FASLODEX": 1.405882098389427, "FORSTEO": 5.697580988489302, "HEPSERA": 9.72577058560791, "HUMALOG": 0.8584717241569794, "HUMIRA": 1.6886362506757535, "IBRANCE": 1.4044785940806357, "KEPPRA": 0.5187636675726386, "KEYTRUDA": 1.283001565436735, "LYRICA": 1.2384738534695847, "MEPOLIZUMAB": 1.542062012373738, "METHOTREXATE": 2.6918085022813925, "MIRABEGRON": 29.39997681632112, "NEXAVAR": 0.6847262340772315, "NORVIR": 8.421295783284583, "OPSUMIT": 0.9126339341308632, "REVLIMID": 7.858423903424564, "RINVOQ": 2.3385270942241543, "SIMPONI": 3.057857714453219, "SPIKEVAX": 0.0435487622855025, "STRIBILD": 8.189066809692145, "SUTENT": 0.6275624393046926, "TERIPARATIDE": 18.35043349921976, "TRUVADA": 7.638610200442364, "VIREAD": 6.488513385059476, "XELJANZ": 1.6529825827051254, "XOFIGO": 15.671315940287217, "XTANDI": 3.104267528445399, "ZOSTAVAX": 1.461297916609171, "null": 0.7617078104766416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11119.json
new file mode 100644
index 00000000000..e3f8850fb34
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11119.json
@@ -0,0 +1 @@
+{"BUMETANIDE": 1024.6447354191264, "null": 0.4323058731990355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1112.json
index cfe86ba3d01..a42e975247d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1112.json
@@ -1 +1 @@
-{"ADEFOVIR": 505.4596392655991, "AFINITOR": 2.5728424348296017, "ATAZANAVIR": 10.962271197995966, "BENZODIAZEPINES": 130.45498989165938, "EMTRIVA": 73.82414740774543, "ENTECAVIR": 78.1716564135315, "EVEROLIMUS": 20.200027659713385, "EXJADE": 5.782874285663376, "HEPSERA": 391.6936320071961, "KYMRIAH": 7.981567287742407, "MIMPARA": 22.28517840000421, "NEXAVAR": 1.6763105635214193, "NORVIR": 24.19163771582701, "OLANZAPINE": 1.7642637949985347, "PANTOPRAZOLE": 14.019854811125455, "STRIBILD": 3.7996629517840974, "TENOFOVIR": 85.43367228710261, "TRUVADA": 6.338317095881918, "VIREAD": 57.434493122318216}
\ No newline at end of file
+{"ARAVA": 0.3899462218091934, "AVANDAMET": 7.415844798664104, "AVANDIA": 6.509628127960115, "BRIDION": 19.163277842780023, "BRILIQUE": 20.422934275514184, "CLOPIDOGREL": 0.8499703486674041, "COMIRNATY": 0.2100225320876358, "EBIXA": 11.699135892539786, "EFAVIRENZ": 5.483628837286245, "FENTANYL": 4.971062134587513, "HARVONI": 1.893422685806995, "IPILIMUMAB": 1.9893538566395728, "KALETRA": 3.343938852244278, "KEPPRA": 1.1675277250972385, "KEYTRUDA": 2.070340600984403, "LACOSAMIDE": 12.777282161773538, "LAMIVUDINE": 4.485437309553661, "LEVETIRACETAM": 0.8383434752053636, "MICARDIS": 3.538110478822175, "OPDIVO": 1.4541606254899682, "PEGINTRON": 0.5752588806280416, "PEMBROLIZUMAB": 3.719051999336321, "PLAVIX": 0.5594556349360196, "RAPISCAN": 50.46396821372571, "SPIKEVAX": 0.1665491655035741, "TELMISARTAN": 5.830511208547697, "TICAGRELOR": 6.731418726769471, "TOZINAMERAN": 0.1037503686116413, "VAXZEVRIA": 0.0534495208022, "VFEND": 1.6861828414930242, "VIMPAT": 16.681126822021746, "null": 3.404229341226112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11120.json
new file mode 100644
index 00000000000..f4fec23d2ab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11120.json
@@ -0,0 +1 @@
+{"AFINITOR": 2.341491718953605, "BENRALIZUMAB": 265.1457268323928, "BUPIVACAINE": 10.346034734851498, "CLOPIDOGREL": 4.469752979966818, "ELIQUIS": 1.4053209175832937, "FENTANYL": 2.838999899233055, "IBRANCE": 1.3914982294718103, "KEYTRUDA": 1.0655032533278503, "NAGLAZYME": 414.2270756115629, "NEXAVAR": 1.7081464871092336, "SIMPONI": 1.800159951251702, "SUTENT": 1.769415155088678, "TRUVADA": 0.6269439736656283, "XELJANZ": 1.7635477475654144, "XOFIGO": 125.78528886115907, "XTANDI": 10.221922409564849, "null": 0.6295518294836424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11121.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11121.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11122.json
new file mode 100644
index 00000000000..88037614c1b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11122.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2986141566020859, "SPIKEVAX": 0.3093620530176117, "SUTENT": 1.5122684530281436, "TOZINAMERAN": 1.0870455749593595, "VAXZEVRIA": 0.1750722019065159, "null": 1.217995507551492}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11123.json
new file mode 100644
index 00000000000..40b827f357a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11123.json
@@ -0,0 +1 @@
+{"ELIQUIS": 9.830684493094791, "PLAVIX": 11.910748064275136, "null": 2.4107535744043096}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11124.json
new file mode 100644
index 00000000000..c191009c53f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11124.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 15.600879400596808, "COMIRNATY": 0.1872392637560367, "ELIQUIS": 32.344742880919846, "null": 1.0752057656982512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11125.json
new file mode 100644
index 00000000000..fb5a17f0407
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11125.json
@@ -0,0 +1 @@
+{"null": 1.1637784968729086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11126.json
new file mode 100644
index 00000000000..1be91f00ab9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11126.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5673692189975877, "FENTANYL": 36.173441129656666, "null": 0.9732254562065742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11127.json
new file mode 100644
index 00000000000..5d61b69ccdc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11127.json
@@ -0,0 +1 @@
+{"ENBREL": 31.179982722865173, "null": 0.6853002941831071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11128.json
new file mode 100644
index 00000000000..2da2c5fb473
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11128.json
@@ -0,0 +1 @@
+{"ATRIPLA": 1.437745738036162, "BUPIVACAINE": 83.63878910292564, "COMIRNATY": 0.1370086935376966, "COSENTYX": 10.17048254313314, "ELIQUIS": 1.66984189569273, "FENTANYL": 13.472696926987572, "LANTUS": 2.157110466041207, "SPIKEVAX": 0.1864690436957548, "VAXZEVRIA": 0.200035178158617, "null": 1.218173716642842}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11129.json
new file mode 100644
index 00000000000..760e78ea8c5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11129.json
@@ -0,0 +1 @@
+{"null": 4.702219858979559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1113.json
index d7222a61f20..fb2917326e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1113.json
@@ -1 +1 @@
-{"ARANESP": 413.8302060432384, "DARBEPOETIN": 230.84390741085903, "ENTRESTO": 4.185427107854594, "FLUTICASONE": 92.21780411189704, "INSULIN": 4.648412507109309, "MICARDIS": 8.19004069031512, "MIMPARA": 26.900931614474924, "RASBURICASE": 146.31354052446963, "SOLIRIS": 3.863269243143953, "VENCLYXTO": 19.549374448162773, "VENETOCLAX": 35.59914642081516, "VILDAGLIPTIN": 65.6311665791848}
\ No newline at end of file
+{"APIXABAN": 2.7366581894904183, "AVANDIA": 4.489160933955906, "CLOPIDOGREL": 0.907359244670116, "COMIRNATY": 0.1417484618649861, "DENOSUMAB": 44.58159574087806, "ELIQUIS": 0.4374005695052297, "ENTRESTO": 3.1617787388566314, "IRBESARTAN": 7.00850753482841, "IRON": 25.107874759829723, "JANUMET": 1.9402737803962848, "JANUVIA": 2.5940617338730334, "JARDIANCE": 1.473424818283652, "KALETRA": 3.889393919103244, "KEPPRA": 1.7768525431199278, "LACOSAMIDE": 10.593833958024645, "LEVETIRACETAM": 2.115235232549741, "LYRICA": 1.7605088396204045, "OLANZAPINE": 2.317084358584484, "SPIKEVAX": 0.110485399538212, "SPIRONOLACTONE": 35.271465129672414, "VAXZEVRIA": 0.0914119494634477, "VIMPAT": 9.6620518278023, "ZYPREXA": 1.5980848446627307, "null": 3.307229881226696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11130.json
new file mode 100644
index 00000000000..f7f505d77ab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11130.json
@@ -0,0 +1 @@
+{"null": 0.3708086001093317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11131.json
new file mode 100644
index 00000000000..9a5c5e4a0fd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11131.json
@@ -0,0 +1 @@
+{"null": 2.9447705698214093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11132.json
new file mode 100644
index 00000000000..77b313d3b48
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11132.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7279670151791403, "null": 0.889013411256888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11133.json
new file mode 100644
index 00000000000..207ba3ddc7f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11133.json
@@ -0,0 +1 @@
+{"null": 4.40329870614908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11134.json
new file mode 100644
index 00000000000..516fb27ef2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11134.json
@@ -0,0 +1 @@
+{"XTANDI": 16.244264038495704, "null": 0.9917769853111772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11135.json
new file mode 100644
index 00000000000..926db37a4ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11135.json
@@ -0,0 +1 @@
+{"FENTANYL": 26.83124180552105, "null": 1.0186014026481849}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11136.json
new file mode 100644
index 00000000000..fab5ca81e48
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11136.json
@@ -0,0 +1 @@
+{"null": 1.22211340837723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11137.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11137.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11138.json
new file mode 100644
index 00000000000..e06149c1b4f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11138.json
@@ -0,0 +1 @@
+{"NAGLAZYME": 380.2819896299943, "null": 0.8812240998721171}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11139.json
new file mode 100644
index 00000000000..130593b36cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11139.json
@@ -0,0 +1 @@
+{"ARAVA": 0.9033758048469938, "ATRIPLA": 2.9910831397415096, "COMIRNATY": 0.0920876210213811, "SPINRAZA": 69.51131926309743, "null": 1.3653943761375285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1114.json
index 619b411d41b..9aae81c151b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1114.json
@@ -1 +1 @@
-{"ENTRESTO": 4.0394517099962135, "KEYTRUDA": 1.4724076008103395, "LANTUS": 2.0420735759786908, "PEGASYS": 2.820045882152264, "SUTENT": 1.1413987084504058, "VELTASSA": 56.25309808655963, "ZOSTAVAX": 3.13892207570108, "null": 1.3331992654846068}
\ No newline at end of file
+{"AVANDIA": 5.728504500486245, "BRIDION": 16.313899374012287, "BRILIQUE": 12.918193368778365, "COMIRNATY": 0.303173651391786, "EBIXA": 27.534798862086973, "FENTANYL": 6.249130685096789, "HARVONI": 4.984759500746836, "KEPPRA": 0.9754819788572274, "LACOSAMIDE": 16.249035453385087, "LEVETIRACETAM": 2.207083209496211, "PEGINTRON": 1.3539639283744935, "SPIKEVAX": 0.1948894717105915, "TOZINAMERAN": 0.2245620707669782, "VAXZEVRIA": 0.1077691017718918, "VIMPAT": 23.20596074028522, "ZYPREXA": 2.965062409514157, "null": 2.456309063389507}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11140.json
new file mode 100644
index 00000000000..43e7044a574
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11140.json
@@ -0,0 +1 @@
+{"ARAVA": 1.2196785746788212, "ATRIPLA": 0.8394652180005359, "AUBAGIO": 3.0609279135121907, "BELIMUMAB": 58.04743129635512, "BENLYSTA": 2.8737229752042093, "CICLOSPORIN": 0.8057718878943534, "COMIRNATY": 0.2271855712649058, "COSENTYX": 2.3262633539865547, "CYMBALTA": 0.8941645331355167, "ELIQUIS": 3.920293598395048, "ENBREL": 1.6582494658825395, "EVENITY": 7.167093533958791, "EXFORGE": 2.7850237261793627, "FORSTEO": 7.635313217323497, "HUMALOG": 2.175895895090062, "HUMIRA": 1.6042778506254387, "IBRANCE": 2.893871331538145, "LANTUS": 3.4330827175385883, "LYRICA": 12.686892763407766, "METHOTREXATE": 1.2587397349113931, "NAGLAZYME": 8.843543160869503, "OMALIZUMAB": 2.778171741274292, "SIMPONI": 3.190517815821006, "SPIKEVAX": 0.0837350164513268, "SPINRAZA": 9.500529832406912, "STRIBILD": 3.0617460029340062, "SUBOXONE": 1.9526814557306291, "SUTENT": 2.2657431380422253, "TOVIAZ": 6.368500708687698, "TOZINAMERAN": 0.4746464090120584, "TRUVADA": 1.266695028130591, "VAXZEVRIA": 0.0578763766632826, "VIAGRA": 7.662366685806326, "XELJANZ": 5.825660251491167, "ZOSTAVAX": 3.5302005072130505, "null": 1.0069161552480217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11141.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11141.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11142.json
new file mode 100644
index 00000000000..661a2a21691
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11142.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 83.43421984516698, "ELIQUIS": 4.987397966953415, "ENOXAPARIN": 23.763461234837607, "FENTANYL": 6.405061695887704, "PLAVIX": 4.901532130784216, "null": 1.926345782953684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11143.json
new file mode 100644
index 00000000000..20e1ed7477a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11143.json
@@ -0,0 +1 @@
+{"ENOXAPARIN": 315.6799896660098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11144.json
new file mode 100644
index 00000000000..ded352c9703
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11144.json
@@ -0,0 +1 @@
+{"null": 0.8400700673806651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11145.json
new file mode 100644
index 00000000000..266d64d458a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11145.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.6507508327929303, "ARAVA": 0.1470940681757806, "ATRIPLA": 5.709238225830615, "BIKTARVY": 1.4295939560459645, "BONVIVA": 5.619036141169437, "CICLOSPORIN": 0.3379235094262847, "CIMZIA": 0.5362690183455243, "COMIRNATY": 0.0223648147173285, "COSENTYX": 0.4567881114613723, "CYMBALTA": 0.5994008527357663, "DEXAMETHASONE": 0.8485529622425318, "ELIQUIS": 1.8806836637945308, "ENBREL": 0.8122081008361256, "ENTRESTO": 1.31739872064069, "ESBRIET": 3.051546410273425, "EVENITY": 70.15579788005445, "EVISTA": 28.2557794538092, "EXJADE": 0.6231353751887404, "FASLODEX": 1.435014785664396, "FENTANYL": 0.573820087501088, "FORSTEO": 26.165878585346945, "HUMALOG": 1.8682678444538892, "HUMIRA": 1.7161123261556448, "IBRANCE": 3.1020783815422317, "IBUPROFEN": 1.3958368027799828, "INCRUSE": 3.305484729785217, "INSULIN": 1.148811725633544, "JANUVIA": 0.6062437995239485, "KEPPRA": 0.7834192373775382, "KEYTRUDA": 0.3028754060696333, "LANTUS": 1.3283750382634023, "LYRICA": 2.605568279124496, "MEPOLIZUMAB": 0.7620163449136885, "METHOTREXATE": 0.5979299614302785, "NUCALA": 0.8513120168240675, "OPSUMIT": 1.1524022655650452, "PREOTACT": 50.47369314178402, "REVATIO": 4.019679794199031, "REVLIMID": 3.4699877599063083, "RINVOQ": 2.633322352995437, "RITUXIMAB": 1.1144033073741506, "SIMPONI": 2.866677624461205, "SPIKEVAX": 0.02699340475248, "STELARA": 0.8674791202320185, "STRIBILD": 9.637133745949392, "SUBOXONE": 3.1651449991164777, "SUTENT": 0.7080036816489609, "TERIPARATIDE": 13.013928960845346, "TOVIAZ": 1.585984192185797, "TOZINAMERAN": 0.0667787178268812, "TRELEGY": 6.00089861119028, "TREMFYA": 1.760641808178977, "TRUVADA": 6.203822384936808, "VAXZEVRIA": 0.0338933908217649, "VIAGRA": 4.435105508680346, "VIREAD": 3.3640297252950155, "XELJANZ": 4.879071051443314, "XOLAIR": 1.175388089688303, "XTANDI": 1.955057222168462, "null": 1.0853887379886409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11146.json
new file mode 100644
index 00000000000..e66f4955e55
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11146.json
@@ -0,0 +1 @@
+{"ABATACEPT": 4.481770542372643, "ADALIMUMAB": 1.251654225423459, "AMINOSALICYLIC": 19.360580322737803, "ARAVA": 1.1951739336698717, "ATRIPLA": 2.307542517430605, "CIMZIA": 2.446939663534019, "COMBIVIR": 47.60456060859282, "COSENTYX": 2.3966795398845906, "CYMBALTA": 3.654288048489728, "HUMALOG": 1.983478399601846, "LYRICA": 4.607866334581137, "OMALIZUMAB": 8.48676698157165, "SPINRAZA": 18.415399745440105, "STELARA": 2.7135226499579512, "TRUVADA": 1.581176055047982, "XELJANZ": 4.389081199067828, "ZOSTAVAX": 8.847077758485396, "null": 0.8944915191473047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11147.json
new file mode 100644
index 00000000000..90384f8d306
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11147.json
@@ -0,0 +1 @@
+{"SPINRAZA": 859.3049643898396}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11148.json
new file mode 100644
index 00000000000..ffe805d65f2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11148.json
@@ -0,0 +1 @@
+{"ATRIPLA": 1.975949043394721, "null": 1.1112596994545272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11149.json
new file mode 100644
index 00000000000..a9cc995add0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11149.json
@@ -0,0 +1 @@
+{"null": 1.0426276596056734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1115.json
index c4fe7aef334..fc3ca336c09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1115.json
@@ -1 +1 @@
-{"ACTOS": 3.094570723585333, "ADEMPAS": 3.204998557492243, "AFINITOR": 2.1305310899788896, "AMINOSALICYLIC": 4.896853183101811, "AUBAGIO": 1.1345195895756206, "BEDAQUILINE": 14.423660005932955, "BENLYSTA": 1.5495535968811234, "BENZODIAZEPINES": 18.90217070148996, "BUDESONIDE": 11.539567980308808, "BYETTA": 1.2392562650010848, "CABOMETYX": 1.75433096075595, "CANCIDAS": 3.486112984420863, "COAPROVEL": 2.9770733210781364, "CYMBALTA": 1.1926827993865097, "DELAMANID": 6.9238733864126285, "DEXAMETHASONE": 1.0084171865853395, "DULOXETINE": 1.8193328930098849, "ENTRESTO": 2.6413713536654835, "EXFORGE": 2.4576294536832552, "EXJADE": 2.671426085233832, "FAMPYRA": 1.279224405496127, "FIRDAPSE": 6.30595620601347, "HEPSERA": 4.202519375968437, "HIZENTRA": 1.4875575464246926, "HUMALOG": 1.1283510349449617, "HUMIRA": 1.6933937070339942, "HYDROCORTISONE": 2.4602424420280644, "IBRANCE": 2.882939020667273, "INLYTA": 2.0215899822768413, "INSULIN": 1.345558037388848, "IRBESARTAN": 1.3813476266207778, "JARDIANCE": 1.2311131860941005, "KEYTRUDA": 1.0492884744771125, "KYMRIAH": 3.0609553439728923, "LACOSAMIDE": 1.448885808587033, "LANTUS": 1.187438096536766, "LEVEMIR": 1.4012638290852577, "LONSURF": 2.0863835900605374, "LYRICA": 1.1211118541921044, "MEKINIST": 1.0749580057654633, "MICARDISPLUS": 8.607866497485936, "NALOXONE": 14.426299324941953, "NINLARO": 4.419237089920904, "NOT": 1.454726912044433, "NOVORAPID": 1.7237417122293692, "NOXAFIL": 2.945177435864435, "NUCALA": 14.982065620990562, "OPSUMIT": 3.3082934855811588, "OZEMPIC": 5.435116850613218, "PANTOPRAZOLE": 2.955336065273546, "PEGASYS": 3.145081888916673, "PEGINTRON": 3.25666084427149, "RASILEZ": 2.0338621189914603, "REVATIO": 1.6823907358531305, "REVLIMID": 9.9817242664763, "RUBRACA": 5.754090876297713, "SILDENAFIL": 3.849831335416373, "SIRTURO": 18.92882110415466, "SOLIRIS": 1.591891292360648, "SPINRAZA": 1.754250879180528, "SPIRONOLACTONE": 6.039902749214058, "SUTENT": 1.800570170552256, "TRACLEER": 1.9449701405890227, "TRELEGY": 1.2782925529515017, "VALSARTAN": 5.013963098025278, "VELTASSA": 20.337569614335195, "VFEND": 1.6281100177578067, "VICTOZA": 2.0288596605025586, "VORICONAZOLE": 1.518217281149273, "XALKORI": 1.6581734953991147, "XARELTO": 1.2781885659028105, "XTANDI": 1.2862546873711116, "XYREM": 5.348963562480917, "ZOSTAVAX": 1.5148863898773992, "ZYPREXA": 1.0582685298810162, "null": 1.5609657843133244}
\ No newline at end of file
+{"null": 4.318280073115711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11150.json
new file mode 100644
index 00000000000..44f7a1dd0b3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11150.json
@@ -0,0 +1 @@
+{"SPINRAZA": 3483.2606846503195, "null": 0.2388410612591641}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11151.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11151.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11152.json
new file mode 100644
index 00000000000..4a864d3313b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11152.json
@@ -0,0 +1 @@
+{"null": 0.7056531463719815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11153.json
new file mode 100644
index 00000000000..22788563a51
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11153.json
@@ -0,0 +1 @@
+{"ARAVA": 0.6554683973858044, "ATRIPLA": 0.4469167372347934, "AUBAGIO": 9.618300459117522, "BENLYSTA": 4.886626512723302, "BUPRENORPHINE": 1.4310606271984965, "BYETTA": 4.561501882742915, "CIMZIA": 3.3132889614062018, "CYMBALTA": 1.199086429624527, "ELIQUIS": 1.0324790612046757, "ENBREL": 1.7415783549840729, "EVENITY": 9.317071321301713, "FENTANYL": 1.145104093606147, "HIZENTRA": 6.167453914614403, "IBRANCE": 3.031787798664392, "JANUMET": 6.77294495281802, "JANUVIA": 3.270677319000443, "JARDIANCE": 1.8577285542516704, "LANTUS": 6.268287497903515, "LEVEMIR": 2.0873432966494376, "LYRICA": 3.124873167245155, "NAGLAZYME": 12.341751546978166, "NUCALA": 1.5466198278580212, "OPSUMIT": 1.2914703236477632, "PEGASYS": 0.563311456143772, "RINVOQ": 5.263853503819379, "SIMPONI": 8.213652266177053, "STELARA": 2.7199510598072223, "SUBOXONE": 1.4866237707588232, "TRACLEER": 1.50485852295716, "TRELEGY": 2.413270662024885, "TREMFYA": 10.556992227374472, "TRUVADA": 0.4724328291945109, "VELTASSA": 8.799023127062497, "XELJANZ": 8.363141088269744, "XTANDI": 2.4496477590400207, "ZOSTAVAX": 7.114486757800115, "null": 1.6959649646261896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11154.json
new file mode 100644
index 00000000000..4be033cc45e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11154.json
@@ -0,0 +1 @@
+{"ADENURIC": 10.768225035299528, "ARAVA": 0.194325439989402, "ATRIPLA": 10.124804598898814, "BUPRENORPHINE": 3.0111933315776684, "BYETTA": 4.104653180950861, "CIMZIA": 1.1359804529265791, "COMIRNATY": 0.3358832291037417, "COSENTYX": 3.489178132248893, "CYMBALTA": 0.6364740467565779, "ELIQUIS": 0.673337816557468, "ENBREL": 4.788828145028314, "EVISTA": 5.698330632482849, "GARDASIL": 0.5658075714968868, "HUMALOG": 0.5226152223083913, "HUMIRA": 4.62800484409362, "IBRANCE": 0.9210763365186472, "JANUMET": 10.246970710871578, "JANUVIA": 8.610673112766573, "KEYTRUDA": 1.1424507905514585, "LYRICA": 1.7444098598789348, "METHOTREXATE": 1.1874477079851742, "SIMPONI": 0.8018881067441921, "SPIKEVAX": 0.2106171059627479, "STRIBILD": 8.63799507832165, "SUTENT": 0.5291749985815916, "TOZINAMERAN": 0.330401203071341, "TRUVADA": 6.650934553243771, "VAXZEVRIA": 0.0995582544673073, "VIREAD": 4.147915273253359, "XELJANZ": 2.234923257509488, "ZOSTAVAX": 14.013213743588787, "null": 0.6568042490622495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11155.json
new file mode 100644
index 00000000000..1dcaa95b9ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11155.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.2413791775415353, "AFINITOR": 1.8429181756221409, "ARAVA": 0.3492506635928379, "ATRIPLA": 0.4297091989024746, "AUBAGIO": 0.6772592377577621, "BENLYSTA": 1.245828322081537, "BIKTARVY": 1.889181051285208, "BONVIVA": 5.677309521948742, "BUPIVACAINE": 3.985250368065417, "BYDUREON": 1.6219584577465749, "CIMZIA": 0.5705388838038767, "CLOPIDOGREL": 0.4167597492742511, "COMIRNATY": 1.5303527363371323, "COSENTYX": 5.865790572639483, "CYMBALTA": 0.3782950278747858, "DOCETAXEL": 1.4011038486482588, "ELIQUIS": 0.318823908159402, "ENBREL": 2.1317359698278544, "ENTRESTO": 0.4863632858978912, "ENTYVIO": 1.090070537606442, "EXFORGE": 1.4974185349948843, "FASLODEX": 1.1422977337618343, "FENTANYL": 0.4263564452043942, "FLEBOGAMMA": 5.6353014240831865, "FORSTEO": 9.959901018564103, "FULVESTRANT": 5.986003486377823, "GARDASIL": 0.674392627881156, "HUMIRA": 1.70937795408811, "IBRANCE": 2.137866065669257, "JAKAVI": 1.0438976490513885, "KEYTRUDA": 0.3158812553330374, "KISQALI": 3.1869202919652992, "LANTUS": 0.6656154934122704, "LEVOFLOXACIN": 0.5625109493102924, "LYRICA": 1.5676393934474238, "MEKINIST": 0.8742354592493724, "METHOTREXATE": 0.977585744787428, "NAGLAZYME": 3.490641462680023, "NEULASTA": 4.518070733397255, "NEXAVAR": 0.3607716429239493, "NUCALA": 0.5884956537777768, "PEGASYS": 0.3104928841774974, "PEMBROLIZUMAB": 1.2153383984683632, "RINVOQ": 2.051991419835044, "ROACTEMRA": 1.734416435406092, "SHINGRIX": 1.494224798669434, "SIMPONI": 2.084665980689273, "SPIKEVAX": 0.9757098788328225, "SPINRAZA": 3.7459468304097903, "STELARA": 0.3834718745878655, "STRIBILD": 0.4467042133786521, "SUTENT": 1.110034940957483, "TOZINAMERAN": 1.2644159605224252, "TRUVADA": 0.3376165983470253, "TWINRIX": 1.8864436786074543, "VAXZEVRIA": 1.5546859786302276, "VOTRIENT": 0.750847642397087, "XELJANZ": 1.5140212905042412, "XOFIGO": 5.570224834524219, "XTANDI": 0.5123216084276717, "ZOSTAVAX": 0.7688475803754404, "null": 0.4901077253315642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11156.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11156.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11157.json
new file mode 100644
index 00000000000..af27a02dee9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11157.json
@@ -0,0 +1 @@
+{"CRESEMBA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11158.json
new file mode 100644
index 00000000000..5ae8964f52a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11158.json
@@ -0,0 +1 @@
+{"ACLASTA": 27.86975414761918, "ANAKINRA": 2.704752446824384, "ARAVA": 1.5122424053738512, "ATRIPLA": 5.517630447506515, "BIKTARVY": 3.0894805104016254, "BUPIVACAINE": 12.822836689269012, "BUPRENORPHINE": 3.053649717834869, "BUSULFAN": 6.291970245581363, "BYETTA": 1.7726412964858298, "CIMZIA": 4.368669896329724, "COMIRNATY": 0.1279607706875371, "COSENTYX": 2.699867954812978, "CYMBALTA": 0.6928462251545395, "ELIQUIS": 1.756229663539656, "ENBREL": 2.683550732594421, "FASLODEX": 1.925914137774303, "FORSTEO": 1.5613209679488256, "HARVONI": 5.399517603808179, "HUMALOG": 3.140837461575573, "HUMIRA": 2.0427819162657173, "IBRANCE": 1.0026555899668603, "LANTUS": 1.7989904372156804, "LEVEMIR": 3.1762262921088857, "LYRICA": 3.1673975766663385, "METHOTREXATE": 30.635544934289346, "NAGLAZYME": 8.016393608331835, "PANTOPRAZOLE": 6.450937181354753, "RINVOQ": 2.828774897854293, "SIMPONI": 1.106310849730919, "SPIKEVAX": 0.0758905788104289, "STELARA": 1.4690736417326884, "STRIBILD": 3.0833051558831768, "SUBOXONE": 1.2987876816496111, "TOZINAMERAN": 0.1290054020001652, "TRUVADA": 1.976052727376297, "XELJANZ": 4.516670576607373, "ZOSTAVAX": 5.864372439445022, "null": 0.8372584624545265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11159.json
new file mode 100644
index 00000000000..04ead4938ab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11159.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 101.3141045569928, "null": 0.8080245494647719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1116.json
index e96553905b1..2a96dbef0e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1116.json
@@ -1 +1 @@
-{"AFINITOR": 1.5535626465698185, "ALISKIREN": 4.446608314713722, "AMINOSALICYLIC": 1.2813175856577497, "APROVEL": 2.980949670500079, "ARANESP": 1.2816665488134251, "ARIPIPRAZOLE": 1.7291823593999651, "BEDAQUILINE": 12.69000757519289, "BRILIQUE": 2.497932622221499, "BUMETANIDE": 4.28868497506558, "CELECOXIB": 3.4054342737739822, "CLOPIDOGREL": 1.1416061997675178, "COAPROVEL": 3.1522324441674123, "COMBIVIR": 1.3173083882976877, "DENOSUMAB": 6.328243870282749, "EMPAGLIFLOZIN": 6.998479867072879, "ENTRESTO": 29.696279267929608, "ESBRIET": 1.4673631789455786, "EXFORGE": 4.283285087509094, "EXJADE": 3.0961584268525693, "FORSTEO": 1.0223071086956377, "FORXIGA": 1.8045519589072725, "HARVONI": 1.6104158106963586, "HUMALOG": 1.3800600178130724, "IBUPROFEN": 1.0260365371720832, "INLYTA": 2.862009334960658, "IRBESARTAN": 6.435437934543185, "IVABRADINE": 29.645190118139265, "JAKAVI": 4.469456395365851, "JANUMET": 1.0536877430221705, "JANUVIA": 2.031461032161722, "JARDIANCE": 1.5701200788651708, "LEVEMIR": 1.2584002892276878, "LYRICA": 1.4265661066863076, "MICARDIS": 12.643692887980867, "MULTAQ": 2.5343356117869105, "NEXAVAR": 1.4369416476230406, "NOT": 2.2236532236778337, "OPSUMIT": 1.1156943468878642, "RASILEZ": 21.579952684977307, "SAMSCA": 33.017386769864274, "SOLIRIS": 1.1255210863201648, "SPIRONOLACTONE": 16.094187136185464, "SUTENT": 1.4478021171977844, "TEKTURNA": 26.68296229833696, "TRACLEER": 2.131973845850877, "VALSARTAN": 21.191445945582103, "VELTASSA": 99.879597427072, "VENETOCLAX": 6.749537019165823, "VFEND": 1.3381733933273166, "VOTRIENT": 1.6160159802724876, "XALKORI": 2.00065086666733, "null": 1.8051043052860969}
\ No newline at end of file
+{"BOTULINUM": 165.60745408303833, "NORVIR": 156.6128739519058, "OLANZAPINE": 13.631916909099038, "null": 1.5662524998571543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11160.json
new file mode 100644
index 00000000000..0c773d6b80a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11160.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 18.579847277266104, "null": 2.422092030673837}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11161.json
new file mode 100644
index 00000000000..aaaccbf1bdf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11161.json
@@ -0,0 +1 @@
+{"TRUVADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11162.json
new file mode 100644
index 00000000000..9532a835de1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11162.json
@@ -0,0 +1 @@
+{"COMBIVIR": 518.9109229694644, "null": 0.7127343957588432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11163.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11163.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11164.json
new file mode 100644
index 00000000000..ebbb9f30321
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11164.json
@@ -0,0 +1 @@
+{"APIXABAN": 50.31116994589158, "AZATHIOPRINE": 124.56196605666882, "IBUPROFEN": 20.954325284871675, "MEPOLIZUMAB": 25.027962803260447, "NUCALA": 14.507027001928282, "OMALIZUMAB": 64.87490353304156, "XOLAIR": 9.540569282855714, "null": 0.3926335650862119}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11165.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11165.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11166.json
new file mode 100644
index 00000000000..eba31bd2245
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11166.json
@@ -0,0 +1 @@
+{"null": 1.9790637343800452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11167.json
new file mode 100644
index 00000000000..9555937e0af
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11167.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2276281533488621, "EXJADE": 7.493857235430455, "JAKAVI": 82.29314769712573, "RUXOLITINIB": 54.863923691472905, "null": 1.0301969968440323}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11168.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11168.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11169.json
new file mode 100644
index 00000000000..a96a50dd56c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11169.json
@@ -0,0 +1 @@
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1117.json
index 3cbd8f4bd95..8bed1b2bf75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1117.json
@@ -1 +1 @@
-{"SPIKEVAX": 46.0654465647587}
\ No newline at end of file
+{"null": 1.3534383220088049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11170.json
new file mode 100644
index 00000000000..cf00c908630
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11170.json
@@ -0,0 +1 @@
+{"RUXOLITINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11171.json
new file mode 100644
index 00000000000..d7f21cbfedf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11171.json
@@ -0,0 +1 @@
+{"BYETTA": 35.15420405709042, "CICLOSPORIN": 4.192987549651323, "EXJADE": 15.402495212187567, "JANUMET": 38.49983358569997, "JANUVIA": 24.422277086002293, "NPLATE": 311.73620254576184, "STELARA": 3.9807590304861016, "null": 0.491691229432515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11172.json
new file mode 100644
index 00000000000..f8d893bf57d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11172.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 11.381478231726168, "null": 0.7360513477162183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11173.json
new file mode 100644
index 00000000000..629a0809ebc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11173.json
@@ -0,0 +1 @@
+{"null": 0.4538419556163846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11174.json
new file mode 100644
index 00000000000..af27a02dee9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11174.json
@@ -0,0 +1 @@
+{"CRESEMBA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11175.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11175.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11176.json
new file mode 100644
index 00000000000..01816efda77
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11176.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 3.828119134697536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11177.json
new file mode 100644
index 00000000000..d31a3aaa5b1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11177.json
@@ -0,0 +1 @@
+{"ADENURIC": 479.8730691576315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11178.json
new file mode 100644
index 00000000000..444588e3028
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11178.json
@@ -0,0 +1 @@
+{"null": 0.6912513918264752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11179.json
new file mode 100644
index 00000000000..032fe3b6c54
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11179.json
@@ -0,0 +1 @@
+{"ELIQUIS": 15.898141239315612, "PLAVIX": 15.064837405666031, "null": 0.9467877619738176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1118.json
index 9b4837adf28..1b7f38c74a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1118.json
@@ -1 +1 @@
-{"ACLASTA": 16.221155519769955, "ADCIRCA": 4.480595491442218, "ADEMPAS": 5.4355459418869145, "AIMOVIG": 1.3303373824435187, "AMBRISENTAN": 5.730729404650674, "APROVEL": 3.1249498107860445, "ARIPIPRAZOLE": 1.465244748135689, "BYDUREON": 2.190424629530429, "CLOPIDOGREL": 1.4429581754932808, "ELIQUIS": 1.805541867238767, "ENTRESTO": 5.915922562817076, "EXFORGE": 8.41077458933646, "FASENRA": 1.2872180648952938, "HUMALOG": 2.28910518880132, "HUMIRA": 1.9943796392258744, "IBRANCE": 1.2238877223727067, "INLYTA": 4.108001222802455, "JARDIANCE": 1.006038077560001, "KYMRIAH": 1.305491811240311, "KYPROLIS": 2.6691477146763685, "LANTUS": 1.4668106835554675, "LEFLUNOMIDE": 2.2599612764483537, "LEVOFLOXACIN": 1.554437946775434, "LYRICA": 3.5289564209797137, "MEPOLIZUMAB": 2.323688576289395, "MICARDIS": 4.16251540948135, "NEULASTA": 1.5819398847790151, "OMALIZUMAB": 1.1160740695224902, "OPSUMIT": 1.117042013668797, "PEMBROLIZUMAB": 1.76049040783949, "PLAVIX": 1.226879166168747, "RASILEZ": 3.2204012504825035, "REVATIO": 1.9704619374615095, "SILDENAFIL": 2.812260876014433, "SOLIRIS": 1.0650033228499471, "SUTENT": 2.330076202578719, "TELMISARTAN": 4.590611781376902, "TOVIAZ": 1.982646549811811, "VALSARTAN": 5.105777875797806, "VELTASSA": 3.57282827245338, "VIAGRA": 3.187241642929831, "XELJANZ": 2.2257939788563963, "XTANDI": 1.3442810453334104, "ZOSTAVAX": 6.037714385944032, "null": 1.2345844464710392}
\ No newline at end of file
+{"ELIQUIS": 5.378188204327646, "MICARDIS": 55.16106784639823, "ZOSTAVAX": 33.04300232734704, "null": 1.1186449119807067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11180.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11180.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11181.json
new file mode 100644
index 00000000000..bd0d9dd7c97
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11181.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5300777669715617, "CYMBALTA": 1.3970127492671705, "ELIQUIS": 1.884890560279622, "JAKAVI": 22.64261785683987, "PEGINTRON": 2.61026036006261, "RUXOLITINIB": 33.47677254032047, "SPIKEVAX": 0.3021841873078953, "VAXZEVRIA": 0.8111165282027253, "null": 0.7717939671423589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11182.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11182.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11183.json
new file mode 100644
index 00000000000..5861639d9b7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11183.json
@@ -0,0 +1 @@
+{"MYCOPHENOLATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11184.json
new file mode 100644
index 00000000000..df36e021113
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11184.json
@@ -0,0 +1 @@
+{"null": 0.7845551032130645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11185.json
new file mode 100644
index 00000000000..d3761e8845e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11185.json
@@ -0,0 +1 @@
+{"ADENURIC": 237.75034501872392, "AFINITOR": 20.32409195654913, "null": 0.3198436507489695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11186.json
new file mode 100644
index 00000000000..1aba0f69993
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11186.json
@@ -0,0 +1 @@
+{"MABTHERA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11187.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11187.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11188.json
new file mode 100644
index 00000000000..585e5876eaa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11188.json
@@ -0,0 +1 @@
+{"ADENURIC": 942.6503084745764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11189.json
new file mode 100644
index 00000000000..2beb6f2587e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11189.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1148895110553946, "ELIQUIS": 2.785269524202369, "FILGRASTIM": 32.08687973890925, "JAKAVI": 48.16858513035238, "NEULASTA": 64.89457263759789, "VAXZEVRIA": 0.1437980958784326, "null": 0.9241453552145724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1119.json
index b8d6ad27730..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1119.json
@@ -1 +1 @@
-{"ADCIRCA": 3.240378589188541, "ADEMPAS": 5.765291014534246, "APROVEL": 1.3141765746371958, "AZILECT": 1.9000714192601351, "BAVENCIO": 1.4820922897197435, "BEDAQUILINE": 1.821472464575284, "BELIMUMAB": 8.327027918230938, "BENZODIAZEPINE": 1.1892452740070547, "BREXPIPRAZOLE": 9.944783703212, "BRIDION": 21.074956304267943, "BUPIVACAINE": 3.9405904733346646, "CARBIDOPA": 2.139381728400978, "CEFUROXIME": 4.6794770789746, "CLOPIDOGREL": 1.7427361257182687, "COAPROVEL": 2.2726369201445618, "COMTAN": 1.1700945716174356, "CUBICIN": 1.4133327704294256, "DACLATASVIR": 2.5939334539815757, "DAPAGLIFLOZIN": 4.758641685074941, "DARZALEX": 1.0336232415898556, "DENOSUMAB": 1.1249103432604994, "DEXMEDETOMIDINE": 2.493666376935629, "EFIENT": 2.465205843994158, "EMGALITY": 26.17744205470865, "ENALAPRIL": 4.593591274828652, "ENOXAPARIN": 1.5668960100659295, "ENTRESTO": 9.148640312502266, "ENTYVIO": 1.1518926464723789, "EXELON": 2.6559787471888487, "EXFORGE": 9.137284867686503, "FASTURTEC": 3.5457856302223734, "FENTANYL": 5.111107537229279, "FLEBOGAMMA": 3.4154665363280765, "FORSTEO": 1.7875689008779003, "FORXIGA": 1.8925578642586296, "GAZYVARO": 2.399455010322553, "GILENYA": 2.119553690057187, "GLIVEC": 1.1438585476956344, "GLUCAGON": 3.3064462273079416, "HYDROCHLOROTHIAZIDE": 2.1469690517506748, "IRBESARTAN": 2.23204754147208, "ISOPHANE": 3.3395468023104846, "IVABRADINE": 6.565062096543902, "JARDIANCE": 1.4334250643491016, "JEVTANA": 3.452865592008124, "KIOVIG": 1.9317431966203515, "KYMRIAH": 1.612011750463832, "LENVIMA": 1.0098903299830804, "LIXIANA": 2.199693311849252, "LYRICA": 1.351973577413733, "MACITENTAN": 4.974155018442401, "MENVEO": 2.278941399083135, "METFORMIN": 1.408580317498744, "MICARDIS": 4.842245579076026, "MICARDISPLUS": 3.765903671417778, "MIDAZOLAM": 3.6412948202447617, "MIRCERA": 4.631393462296765, "MULTAQ": 1.3018179577208906, "NAGLAZYME": 1.2007192076138524, "NEULASTA": 1.6645619551019557, "OBINUTUZUMAB": 1.574065708596363, "OMALIZUMAB": 1.1292086126220096, "OPSUMIT": 1.6158620987668202, "OZEMPIC": 2.0108451744287623, "PERJETA": 1.4152454262967002, "PLAVIX": 1.159690663630509, "PRIVIGEN": 2.029604099352155, "PROPRANOLOL": 1.5984329560582835, "RANEXA": 2.9908112504184854, "RAPISCAN": 14.938304259971554, "RASILEZ": 4.021953918358298, "REBETOL": 1.0456641758458205, "REGADENOSON": 16.443055458439936, "REMICADE": 1.8934744052164256, "REVATIO": 2.121749830671444, "SAMSCA": 7.826327020489997, "SILDENAFIL": 3.196709479030938, "SOVALDI": 1.0058629137976032, "SPIRONOLACTONE": 1.9331170316836197, "STALEVO": 1.0353589325885733, "SUFENTANIL": 4.48086459989658, "TAMIFLU": 1.4469544642243957, "TELMISARTAN": 3.3554718293230743, "TICAGRELOR": 1.4062186477483094, "TOBRAMYCIN": 2.054228825580104, "TOLVAPTAN": 12.857949718216082, "TORISEL": 1.6822880532376217, "VALSARTAN": 14.610005851876169, "VEKLURY": 1.930208283733969, "VIAGRA": 2.1380259322970727, "XOLAIR": 1.6198201871146394, "ZIAGEN": 1.2042858353955233, "ZYPADHERA": 3.847174014593083, "null": 2.328870092474373}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11190.json
new file mode 100644
index 00000000000..90b329f695f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11190.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 0.8905645148575417, "null": 0.3884546592643642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11191.json
new file mode 100644
index 00000000000..e1a818d6c31
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11191.json
@@ -0,0 +1 @@
+{"JANUMET": 148.5924779612779}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11192.json
new file mode 100644
index 00000000000..0d0a6d8daee
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11192.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2717512478949238, "JANUMET": 36.033271581905616, "JANUVIA": 13.084852943744393, "VAXZEVRIA": 2.5600212102416813, "null": 0.1934020444021182}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11193.json
new file mode 100644
index 00000000000..2057f6f84f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11193.json
@@ -0,0 +1 @@
+{"null": 0.7934161955149596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11194.json
new file mode 100644
index 00000000000..d6eb28adf98
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11194.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.932530638767828, "ADCIRCA": 5.445091695802707, "ANAGRELIDE": 66.15655087495634, "ANAKINRA": 4.068857046522883, "ARANESP": 2.4006093800247585, "ARAVA": 0.1154766000228099, "ARIPIPRAZOLE": 1.0768689814590884, "AVASTIN": 2.778922906628784, "AZACITIDINE": 6.040376250849704, "AZATHIOPRINE": 4.460267221710462, "BEVACIZUMAB": 3.5335438349067445, "BUSULFAN": 2.046340590533707, "BYETTA": 1.6095842484435676, "CELLCEPT": 1.8862572843472905, "CICLOSPORIN": 4.981906812668099, "CIMZIA": 0.3938816963182437, "CLOPIDOGREL": 0.6110073824242633, "COMBIVIR": 4.313373918308522, "COMIRNATY": 0.1990042949177364, "COSENTYX": 0.749648036625381, "CYMBALTA": 0.3958655400560771, "CYTARABINE": 3.441761004046104, "DASATINIB": 7.765346958783179, "DEXAMETHASONE": 1.4894994164729194, "EFAVIRENZ": 3.8518548863923776, "ELIQUIS": 0.3336294415960249, "EXJADE": 10.18890036612246, "EXVIERA": 5.306851448982666, "GARDASIL": 0.8178907658858532, "GAZYVARO": 5.186336641566154, "GLIVEC": 4.059251768089615, "HIZENTRA": 1.2652215899540042, "HUMALOG": 0.2592839477428575, "HYDROXYCARBAMIDE": 48.70300139290743, "IBRUTINIB": 14.468967682550687, "ICLUSIG": 2.951571122237291, "IMATINIB": 6.240926892437125, "JAKAVI": 98.28535254369685, "JANUMET": 1.3065753604185466, "JANUVIA": 1.7005830328038478, "KALETRA": 1.8062502599115855, "KEPPRA": 0.3238706102418153, "KYMRIAH": 1.5863105669941042, "LAMIVUDINE": 7.7809052219685775, "LANTUS": 0.4078491314399453, "LEMTRADA": 2.0481813709134262, "LEVETIRACETAM": 1.2726596312399274, "LEVOFLOXACIN": 0.5260570605046806, "MABTHERA": 4.46286423994748, "MERCAPTOPURINE": 4.7305053561537616, "METFORMIN": 15.579364799229324, "METHOTREXATE": 0.9486464616131116, "MYCOPHENOLATE": 2.2510055548893777, "NEULASTA": 2.4977526448599527, "NEXAVAR": 0.3775038344937197, "NILOTINIB": 9.987489118933468, "NPLATE": 8.178013985838023, "OCALIVA": 6.826762285652174, "OLANZAPINE": 1.0130390037114136, "OPDIVO": 0.7995005568080551, "OPSUMIT": 0.7759389099918574, "OPTIMARK": 0.7905447947374099, "OZEMPIC": 9.547717579150437, "PEGASYS": 3.061192303909928, "PEGINTRON": 1.0503759889442617, "RITUXIMAB": 1.650845273327385, "RUXOLITINIB": 88.1432121065915, "SOLIRIS": 3.816596887148585, "SPIKEVAX": 0.1656045862493468, "SPRYCEL": 4.41393720894199, "STELARA": 1.0450790193270456, "TASIGNA": 4.731647066417034, "TOZINAMERAN": 0.2518034367433117, "TRACLEER": 0.7431283159008989, "VAXZEVRIA": 0.0593864588929605, "VENCLYXTO": 9.042304972113335, "VENETOCLAX": 9.377468403728365, "XOLAIR": 0.4066120438556322, "ZOSTAVAX": 0.5499410920520956, "ZYPREXA": 0.5707127221918566, "null": 1.004231092324321}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11195.json
new file mode 100644
index 00000000000..149c89bde8f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11195.json
@@ -0,0 +1 @@
+{"null": 0.7258599884531305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11196.json
new file mode 100644
index 00000000000..54fc9ebb9d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11196.json
@@ -0,0 +1 @@
+{"ATRIPLA": 31.002743108773984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11197.json
new file mode 100644
index 00000000000..5f8b37c2664
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11197.json
@@ -0,0 +1 @@
+{"ABATACEPT": 3.816607061082314, "ADALIMUMAB": 1.38696403514088, "AMINOSALICYLIC": 16.471506387492404, "ATRIPLA": 1.0879160253663172, "CIMZIA": 2.0849360857654826, "COMIRNATY": 0.5373161242361216, "COSENTYX": 13.97751363211443, "ELIQUIS": 1.1063422728647396, "ENTYVIO": 11.333310285782302, "HUMIRA": 6.445031853847921, "PEGASYS": 2.3040922480987542, "SIMPONI": 12.132794992537834, "SPIKEVAX": 0.1841650619375489, "STELARA": 3.0788223528479715, "TOZINAMERAN": 1.094537331132652, "VAXZEVRIA": 0.149080024201128, "XELJANZ": 3.2985894268541966, "ZOSTAVAX": 2.6044379890489746, "null": 0.4827447498683797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11198.json
new file mode 100644
index 00000000000..c3f468a6051
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11198.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 10.83797375116196, "ANAKINRA": 114.69203175630896, "COMIRNATY": 0.2128977123727967, "COSENTYX": 8.457833616332053, "null": 0.2418441187705744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11199.json
new file mode 100644
index 00000000000..799cd3431f0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11199.json
@@ -0,0 +1 @@
+{"ATRIPLA": 12.80455306485301, "STRIBILD": 11.455756623183191, "ZOSTAVAX": 7.256759455610148, "null": 0.5776407856661185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/112.json
index aa89671e711..6b2b9d485d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/112.json
@@ -1 +1 @@
-{"ARANESP": 3.2158832903036134, "AZATHIOPRINE": 18.110542398735, "CELLCEPT": 6.821366774834101, "CIALIS": 470.24417195106304, "CICLOSPORIN": 6.885296488905276, "COSENTYX": 5.072209229141919, "JAKAVI": 16.530742891415514, "MYCOPHENOLATE": 29.976872359533868, "STELARA": 2.5809630700901924, "VEMURAFENIB": 103.93834272041644, "VFEND": 38.725050026833394, "VIAGRA": 5.148200600517941, "VORICONAZOLE": 83.87006766051883, "ZELBORAF": 25.578306046276357, "ZOSTAVAX": 25.115868048007226}
\ No newline at end of file
+{"null": 2.234965918179927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1120.json
index 8d2e6bcab49..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1120.json
@@ -1 +1 @@
-{"ACLASTA": 126.10292480836006, "ARAVA": 2.4242869596020173, "CIMZIA": 3.4934455283471904, "CYMBALTA": 4.173067952117106, "ELIQUIS": 2.531849946363495, "ESOMEPRAZOLE": 20.007416103556096, "JANUVIA": 6.157339770223707, "LEFLUNOMIDE": 22.28836922140312, "METHOTREXATE": 44.60910514567497, "MICARDIS": 10.497054259539944, "MYCOPHENOLATE": 16.133871072828164, "OFEV": 13.753948699635435, "RITUXIMAB": 116.12787142112695, "SILDENAFIL": 17.986525269218156}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11200.json
new file mode 100644
index 00000000000..39d760d1c74
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11200.json
@@ -0,0 +1 @@
+{"ATRIPLA": 13.64105297037372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11201.json
new file mode 100644
index 00000000000..731a739207a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11201.json
@@ -0,0 +1 @@
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11202.json
new file mode 100644
index 00000000000..8792549e1d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11202.json
@@ -0,0 +1 @@
+{"EPCLUSA": 72.47677420815941, "INCIVO": 42.50509988842207, "NEXAVAR": 11.543509920376112, "PEGASYS": 19.099931836037594, "PEGINTERFERON": 21.26076367312149, "PEGINTRON": 10.715034833200743, "RIBAVIRIN": 21.08094225289485, "SOVALDI": 47.82313725936973, "null": 0.1467638535182246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11203.json
new file mode 100644
index 00000000000..e6e67aee351
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11203.json
@@ -0,0 +1 @@
+{"null": 1.5228310199198265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11204.json
new file mode 100644
index 00000000000..1b11af922aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11204.json
@@ -0,0 +1 @@
+{"BRILIQUE": 17.176362782619623, "CLOPIDOGREL": 7.04404517729167, "COMIRNATY": 1.297293163724044, "ELIQUIS": 8.077752606521097, "ENOXAPARIN": 8.298612168030408, "PLAVIX": 5.386013062339346, "SPIKEVAX": 0.3316996701183292, "VAXZEVRIA": 1.4792466519212872, "null": 1.351038786171369}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11205.json
new file mode 100644
index 00000000000..7e8dd4916d4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11205.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 8.391223215807726, "COMIRNATY": 0.1889984891305322, "ELIQUIS": 17.836856431095004, "HEMLIBRA": 180.42468064031465, "VAXZEVRIA": 0.2834254973089237, "null": 1.2408414437194524}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11206.json
new file mode 100644
index 00000000000..6ed6d3e8c0b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11206.json
@@ -0,0 +1 @@
+{"OPSUMIT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11207.json
new file mode 100644
index 00000000000..68a627a299a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11207.json
@@ -0,0 +1 @@
+{"VIAGRA": 112.22790155085262, "null": 1.207985439188397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11208.json
new file mode 100644
index 00000000000..0c904d021b5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11208.json
@@ -0,0 +1 @@
+{"null": 1.0367874321943449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11209.json
new file mode 100644
index 00000000000..3e74dcd7706
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11209.json
@@ -0,0 +1 @@
+{"STEROIDS": 16.07254395745642, "null": 172.605369211968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1121.json
index e3c12674d7b..4a6f79ccb1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1121.json
@@ -1 +1 @@
-{"ACLASTA": 42.824865341921225, "ADCIRCA": 16.461796133706606, "AFINITOR": 9.092616237261607, "ANAKINRA": 8.832667405605523, "APIXABAN": 3.984090147810893, "ARAVA": 1.1768843761778522, "CAPECITABINE": 3.81934977638114, "CIMZIA": 1.2772154011911474, "CLOPIDOGREL": 5.759557969354538, "COSENTYX": 2.3694633946873718, "CYMBALTA": 2.4556327824897144, "ENBREL": 1.4298790541228523, "ENTRESTO": 5.326675410249894, "ESOMEPRAZOLE": 6.814384765010442, "EXFORGE": 11.51735911103616, "EXJADE": 5.634849481211608, "JANUVIA": 3.739223912193413, "JARDIANCE": 1.8504526094090472, "METHOTREXATE": 9.399491748967844, "OMALIZUMAB": 7.144644246218551, "PANTOPRAZOLE": 30.956320520812373, "RASILEZ": 18.59601325356756, "RITUXIMAB": 24.942121355388263, "VALSARTAN": 14.340032255750485, "XOLAIR": 2.381075546271854, "null": 1.2036111796245508}
\ No newline at end of file
+{"ABILIFY": 24.34659861730957, "BUSULFAN": 9.984890021961323, "COMIRNATY": 0.193812340810216, "CYMBALTA": 2.920468294537703, "KEPPRA": 3.1627882763509585, "LEVETIRACETAM": 7.871720056272367, "OPTIMARK": 6.205003088637609, "SPIKEVAX": 0.1685805541728741, "null": 1.278893739374296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11210.json
new file mode 100644
index 00000000000..f2f718488d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11210.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.149208881819028, "MEPOLIZUMAB": 33.354061536030514, "NUCALA": 8.197821822406942, "PEGASYS": 2.8273863177485663, "null": 1.2424881575565103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11211.json
new file mode 100644
index 00000000000..2da50e38ae2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11211.json
@@ -0,0 +1 @@
+{"AMINOSALICYLIC": 46.333141196941135, "BEDAQUILINE": 93.69305410831306, "BUDESONIDE": 62.32785045277529, "MEPOLIZUMAB": 33.13517907411721, "null": 0.1406585727192267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11212.json
new file mode 100644
index 00000000000..94badb8ca05
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11212.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 25.707633823946264, "ARAVA": 0.6256715702565667, "AVAMYS": 30.475380767345754, "BENLYSTA": 1.6347279390279974, "BENRALIZUMAB": 126.47872099501672, "BUDESONIDE": 10.174278711507355, "COMIRNATY": 0.0833867453208642, "COMTAN": 6.939904049131369, "COSENTYX": 2.1678719353245373, "CYMBALTA": 0.4596678101506861, "DUAKLIR": 162.67305660692028, "ELIQUIS": 0.3280547025691691, "ENTRESTO": 0.9841553555916914, "ESBRIET": 2.457834026460564, "FLUTICASONE": 28.51150452412092, "GLYCOPYRRONIUM": 81.47849535863254, "HIZENTRA": 4.46688184690968, "IBRANCE": 0.7370776849334418, "INCRUSE": 13.311410504466622, "IRON": 17.353996139877957, "MEPOLIZUMAB": 73.46591168697522, "METHOTREXATE": 1.274919201697826, "NUCALA": 26.592438097485545, "OFEV": 2.947600543336244, "OMALIZUMAB": 52.82794433218907, "OPSUMIT": 2.9237322777121864, "PEGASYS": 0.7688834887545256, "RELVAR": 11.518009619141704, "SPIKEVAX": 0.2138260027283747, "SUTENT": 0.4681719307967942, "TOZINAMERAN": 0.3016830811747645, "TRELEGY": 4.375855661394247, "UMECLIDINIUM": 24.443165832476275, "VAXZEVRIA": 0.0498561326863855, "XELJANZ": 1.8384901207534068, "XOLAIR": 16.468371354490174, "null": 0.5753263835269631}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11213.json
new file mode 100644
index 00000000000..28842529a40
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11213.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 3.247077537924551, "COMIRNATY": 0.3774676982379737, "ELIQUIS": 0.9610784765316724, "INCRUSE": 18.44765925060612, "KAFTRIO": 63.78610513550397, "MEPOLIZUMAB": 35.08631641109543, "ORKAMBI": 47.25802614294438, "RELVAR": 14.931764189827392, "SPIKEVAX": 0.1813039164147656, "TRELEGY": 8.998570516505719, "VAXZEVRIA": 0.104387732926154, "XOLAIR": 2.3035979674062435, "null": 1.5269715509380968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11214.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11214.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11215.json
new file mode 100644
index 00000000000..121aa39e87d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11215.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 167.39246541651318, "COMIRNATY": 0.1390104094807799, "LEVOFLOXACIN": 12.07798111950329, "MEPOLIZUMAB": 52.755494284713066, "NUCALA": 16.44481303103854, "null": 1.1694669960027082}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11216.json
new file mode 100644
index 00000000000..db84ccdf383
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11216.json
@@ -0,0 +1 @@
+{"ADCIRCA": 49.06237616204141, "COMIRNATY": 0.3067826572417814, "NUCALA": 21.646203144292397, "XOLAIR": 4.97966480795533, "null": 1.4673490888148186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11217.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11217.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11218.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11218.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11219.json
new file mode 100644
index 00000000000..f6cd65403d0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11219.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.1940851915218615, "ARAVA": 0.7533880273600314, "AZATHIOPRINE": 2.64434565486228, "BIKTARVY": 3.2673801541628475, "BRAFTOVI": 4.804410649424433, "CELLCEPT": 12.449632103474682, "CIALIS": 154.86879200899787, "CICLOSPORIN": 16.999349490840775, "CIMZIA": 1.7492596282993305, "COMIRNATY": 0.0463089304068605, "COSENTYX": 2.150638860495261, "DEXAMETHASONE": 1.0301794233073749, "ELIQUIS": 0.6562868781960073, "GLIVEC": 7.430656658134777, "HUMALOG": 0.4746319747838055, "HUMIRA": 3.0997302442422336, "JAKAVI": 38.2938281447495, "KEYTRUDA": 0.4881959167038766, "MEKINIST": 4.029436060528416, "METHOTREXATE": 3.1499399047769336, "MYCOPHENOLATE": 5.615078138353351, "NEXAVAR": 3.585907864689541, "PEGASYS": 0.5091216741374248, "REMICADE": 6.967829054857897, "RINVOQ": 2.8734146081110303, "RITUXIMAB": 2.209092120937684, "ROACTEMRA": 2.428719251920948, "RUXOLITINIB": 60.1541555209201, "SIMPONI": 1.9686808119695525, "STELARA": 10.830146839571531, "SUTENT": 0.3336146323259252, "TOZINAMERAN": 0.120455475165524, "VEMURAFENIB": 148.64567988873424, "VFEND": 12.31691794009347, "VIAGRA": 2.186302000294299, "VORICONAZOLE": 28.479407296174777, "XELJANZ": 2.9924773028610328, "XOLAIR": 1.9011824095179244, "ZELBORAF": 113.2547770819626, "ZOSTAVAX": 0.9167263516517526, "null": 0.6761173902593929}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1122.json
index 4d40ebf054f..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1122.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.7337075929640453, "AFINITOR": 2.499541575222969, "APIXABAN": 2.3442386051793638, "BEVACIZUMAB": 19.40030522254752, "CICLOSPORIN": 1.611521376069838, "CIMZIA": 2.2017891762489423, "EXFORGE": 6.671122559105506, "INLYTA": 4.925452566458702, "METHOTREXATE": 12.986421946421276, "OMALIZUMAB": 6.992976739592857, "RASILEZ": 13.765266594494973, "RITUXIMAB": 32.839848477148415, "SILDENAFIL": 8.626600819360837, "SUTENT": 1.9503597841471751, "XELJANZ": 1.111939231628736, "null": 1.0532656066370674}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11220.json
new file mode 100644
index 00000000000..cba7ec5d56f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11220.json
@@ -0,0 +1 @@
+{"null": 1.095171138256115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11221.json
new file mode 100644
index 00000000000..48f549af39a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11221.json
@@ -0,0 +1 @@
+{"STELARA": 9.544844113240032, "null": 0.8850877627558864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11222.json
new file mode 100644
index 00000000000..2d33a16ae0a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11222.json
@@ -0,0 +1 @@
+{"ARAVA": 0.7489467452604728, "AZATHIOPRINE": 15.958080943523246, "CELLCEPT": 15.481409012307298, "CICLOSPORIN": 13.302920519384296, "COMIRNATY": 0.0229785444191701, "COSENTYX": 1.321147331462473, "ENTYVIO": 2.6684145307840272, "HUMIRA": 2.466184976551076, "JAKAVI": 30.7952111940626, "KEYTRUDA": 1.6376883804846378, "LIBTAYO": 71.47440420971948, "MEKINIST": 4.640222404996487, "MYCOPHENOLATE": 32.02257602776981, "NEXAVAR": 8.954914664525031, "REVLIMID": 15.776523717308711, "RINVOQ": 6.107475566061689, "RUXOLITINIB": 55.94068966087306, "SIMPONI": 1.3064197507866813, "SORAFENIB": 28.353003645537928, "STELARA": 4.26876753882084, "TACROLIMUS": 21.68212317763691, "TREMFYA": 5.695430541898567, "VEMURAFENIB": 116.26438322960816, "VFEND": 34.13045195402731, "VORICONAZOLE": 95.47253107069452, "XELJANZ": 2.8785920852918143, "ZELBORAF": 69.61553247999973, "ZOSTAVAX": 1.6457897004198143, "null": 0.4943389247960081}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11223.json
new file mode 100644
index 00000000000..b139dacbc3b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11223.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 15.514661088122573, "METHOTREXATE": 24.355468824624463, "null": 0.4380007937505467}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11224.json
new file mode 100644
index 00000000000..b53013189dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11224.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 14.152908455273122, "null": 0.5423170052884647}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11225.json
new file mode 100644
index 00000000000..ad8fa14463a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11225.json
@@ -0,0 +1 @@
+{"ESMYA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11226.json
new file mode 100644
index 00000000000..f103ee0bdfa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11226.json
@@ -0,0 +1 @@
+{"null": 1.5595324857006607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11227.json
new file mode 100644
index 00000000000..adea616a844
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11227.json
@@ -0,0 +1 @@
+{"null": 1.6086976435080844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11228.json
new file mode 100644
index 00000000000..55d4257a072
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11228.json
@@ -0,0 +1 @@
+{"null": 0.9337166011283496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11229.json
new file mode 100644
index 00000000000..824b728e9e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11229.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 24.851566003065315, "ASPARAGINASE": 16.095596665461926, "AZACITIDINE": 21.238791734885112, "BORTEZOMIB": 55.40116470785328, "BUSULFAN": 13.388025783971733, "CELLCEPT": 3.0218010391366925, "CICLOSPORIN": 6.525853726283177, "COMIRNATY": 0.0369936185055296, "CUBICIN": 139.58746271416047, "CYTARABINE": 12.256940557521672, "DAPTOMYCIN": 164.40288221150644, "DEXAMETHASONE": 5.928865913947907, "DOXORUBICIN": 15.23226271758612, "FILGRASTIM": 43.407933374971314, "KEYTRUDA": 0.8855500020131566, "METHOTREXATE": 3.0226358820732258, "MYCOPHENOLATE": 9.481240695555716, "OPSUMIT": 1.892182664280102, "PEGASYS": 1.7809135187312233, "PEGINTERFERON": 5.882792861410981, "RITUXIMAB": 4.134548093693012, "SOLIRIS": 5.97143245501834, "STELARA": 1.8403094239767304, "null": 0.5661643351458576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1123.json
index b298b07f478..849334b9f08 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1123.json
@@ -1 +1 @@
-{"ACLASTA": 10.003419313012758, "ALEMTUZUMAB": 1.723242486263229, "ANAKINRA": 5.194217442138185, "APIXABAN": 1.2390284504090172, "APROVEL": 4.2051086799948365, "BENLYSTA": 1.075740481741789, "BUPIVACAINE": 1.4804852996400553, "CABOMETYX": 1.0970760677515976, "CLOPIDOGREL": 1.230256865327487, "COMIRNATY": 1.0162071935881651, "COMTAN": 4.235586943060363, "CYMBALTA": 2.1484578939372003, "DOCETAXEL": 1.0352681803646866, "ENBREL": 1.9962228611230377, "ENTRESTO": 2.816196528686957, "ESBRIET": 1.2764819223332788, "EXFORGE": 15.446809599806995, "FORSTEO": 1.633766635126792, "FORXIGA": 1.001380669103169, "HYDROCHLOROTHIAZIDE": 7.503337707575477, "IMATINIB": 4.052033348550526, "INFLECTRA": 22.165841597516543, "INFLIXIMAB": 13.07389755788197, "INLYTA": 2.1288792481236265, "IRBESARTAN": 1.9478938201174, "JANUVIA": 1.0999168498802063, "LENVIMA": 1.5238823235609729, "MEPOLIZUMAB": 1.2398048446376944, "METHOTREXATE": 2.221300094559552, "MICARDIS": 6.198692505277972, "RASILEZ": 14.248234425507968, "RITUXIMAB": 12.25740607277717, "SIMPONI": 1.2480163212932356, "SUTENT": 2.0213474368525723, "TELMISARTAN": 3.6105456277226993, "VALSARTAN": 10.071686878996095, "XTANDI": 1.0102464523664714, "null": 1.3888290767254483}
\ No newline at end of file
+{"ABILIFY": 2.0700574810024293, "ARIPIPRAZOLE": 2.7455099445865887, "AVAMYS": 2.841887861570987, "BUPRENORPHINE": 3.031768068992449, "COMBIVIR": 3.8574475549439966, "COMIRNATY": 0.0842362073499452, "CYMBALTA": 1.0104268883738203, "FENTANYL": 1.440355435646321, "GARDASIL": 4.851267571153799, "INFANRIX": 11.203989528457498, "KAFTRIO": 10.76606473711668, "KEPPRA": 3.6765973924171336, "LEVETIRACETAM": 5.210961635223912, "SPIKEVAX": 0.0677754099417005, "SUBOXONE": 5.868751159677377, "TOZINAMERAN": 0.2605483310184867, "VAXZEVRIA": 0.105435129962322, "ZOSTAVAX": 1.0286884441085409, "ZYPREXA": 0.9786512229340902, "null": 4.556365715509854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11230.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11230.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11231.json
new file mode 100644
index 00000000000..81c872e277e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11231.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.973729101016808, "ABILIFY": 7.899665824778323, "ABRAXANE": 5.857026410008794, "AFINITOR": 0.4500383209722621, "ALEMTUZUMAB": 4.887658416117423, "AMIKACIN": 3.1385542133827, "APIDRA": 0.8061550428812024, "ARANESP": 1.2926009110672487, "ARAVA": 0.4257678721948596, "ASPARAGINASE": 6.086755783066449, "ATAZANAVIR": 1.7293722360124586, "ATRIPLA": 0.0658696482915781, "AUBAGIO": 1.2328053558335574, "AVANDIA": 0.3815462662647685, "AVASTIN": 0.6709403067292318, "AVONEX": 21.753311287132703, "AZATHIOPRINE": 1.964222061756817, "AZTREONAM": 11.905407732441558, "BASILIXIMAB": 4.604278733726862, "BENLYSTA": 3.388710284263295, "BIKTARVY": 1.6410624829885638, "BLINCYTO": 15.104143227457088, "BORTEZOMIB": 3.462095060056636, "BRIVIACT": 2.374634012613188, "BUDESONIDE": 0.332263954449089, "BUPRENORPHINE": 0.5114642641965442, "BUSILVEX": 8.324231707801951, "BUSULFAN": 6.012793322062258, "BYETTA": 0.4559905986978863, "CANAKINUMAB": 46.722405571583664, "CANCIDAS": 2.243105678053489, "CARMUSTINE": 3.13841633132439, "CEFTAROLINE": 101.24909970862343, "CELLCEPT": 3.0628457134237057, "CICATRIZANTS": 177.1807280797498, "CICLOSPORIN": 5.180134292373625, "CIMZIA": 2.5444162646675825, "CINRYZE": 6.843836990133736, "COMIRNATY": 0.0360266989916251, "COSENTYX": 3.351852285539036, "CUBICIN": 18.17486335122408, "CYMBALTA": 0.618101913353121, "CYTARABINE": 4.552520600362821, "DAPTOMYCIN": 39.31743736502168, "DEXAMETHASONE": 2.4028414597981507, "DOCETAXEL": 0.936868659859666, "ELIQUIS": 0.490998646777695, "ENBREL": 1.8826433334652648, "ENTRESTO": 1.0723085910776635, "ENTYVIO": 0.5881218725775234, "ESBRIET": 0.8995191218378864, "EXJADE": 3.2893348568598206, "EYLEA": 0.8956375679550671, "FAMPRIDINE": 17.74879486115874, "FASENRA": 0.8920986078682149, "FENTANYL": 0.439636101250745, "FILGRASTIM": 2.398277542913114, "FORSTEO": 0.2947256677810957, "FULVESTRANT": 2.446841323255497, "GANCICLOVIR": 3.48373986014909, "GARDASIL": 0.2664063464328902, "HIZENTRA": 9.880955893343156, "HUMALOG": 2.305603823641426, "HUMAN": 1.837073596662576, "HUMIRA": 1.396848953038743, "HYDROCORTISONE": 1.4445441197524331, "IBRANCE": 0.9219234976205491, "IBUPROFEN": 0.8146860748323992, "INCRUSE": 2.921068007709645, "INSULIN": 1.4752964590754123, "JANUVIA": 0.7503860077427845, "JARDIANCE": 0.64931907212408, "KALETRA": 1.9525951552604093, "KEPPRA": 0.8278020558849258, "KEYTRUDA": 0.519011952755828, "KYMRIAH": 1.5632541608874593, "LANTUS": 2.227977083333554, "LEMTRADA": 1.0560367665128063, "LEVEMIR": 2.171936236879832, "LEVETIRACETAM": 0.5239968443227233, "LEVOFLOXACIN": 1.4376045634628982, "LYRICA": 1.772877964076628, "MELATONIN": 2.246148424969404, "MELPHALAN": 4.4873874708435535, "METHOTREXATE": 2.678190918297961, "MYCOPHENOLATE": 5.953067724101575, "NEULASTA": 1.1089814796490267, "NOT": 1.828414812115839, "NPLATE": 1.1113594684445594, "NUCALA": 0.6336636670711869, "OFEV": 0.7686573531650809, "OPSUMIT": 2.5906582719453186, "OPTIMARK": 0.7790422216295674, "ORKAMBI": 12.543138387665088, "PEGASYS": 3.1196453740335053, "PEGINTERFERON": 1.7446160518601217, "PEGINTRON": 2.660549738248412, "PLAVIX": 0.358421166391003, "PRIVIGEN": 3.51374180147719, "REMICADE": 6.504771481085286, "REVATIO": 1.5301820088444151, "REVLIMID": 2.184876040133111, "RINVOQ": 1.2781709688057643, "RITUXIMAB": 1.497045441656105, "ROACTEMRA": 1.9790270169782893, "RUCONEST": 4.8779349148566284, "SAXENDA": 0.7026815628120089, "SIMPONI": 2.131760812282028, "SOLIRIS": 4.1486442267861685, "SPIKEVAX": 0.0876607136562079, "STELARA": 3.827844792066186, "SUBOXONE": 1.988245269174228, "SUTENT": 0.3875805186301944, "SYNAGIS": 2.301063998896947, "TACROLIMUS": 3.4611760965196705, "TAMIFLU": 1.4100440753495238, "TOBRAMYCIN": 6.208773911674653, "TOCILIZUMAB": 3.916458845628713, "TOZINAMERAN": 0.1450959550045418, "TRACLEER": 2.826765265686747, "TREMFYA": 2.661842215760561, "VAXZEVRIA": 0.0129028538829197, "VFEND": 1.137857825798746, "VIAGRA": 0.9725219331676928, "VICTOZA": 0.7464808781922163, "VOTRIENT": 0.61106588738132, "XELJANZ": 3.1311888263918357, "XOLAIR": 1.1768945864065046, "XTANDI": 0.8608887463937507, "ZOSTAVAX": 0.9612064925868696, "ZYPREXA": 0.6494043868555796, "null": 1.1684891914306423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11232.json
new file mode 100644
index 00000000000..6cc0aea1106
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11232.json
@@ -0,0 +1 @@
+{"SIMPONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11233.json
new file mode 100644
index 00000000000..940a1dcc27c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11233.json
@@ -0,0 +1 @@
+{"CICATRIZANTS": 13749.967313847352, "null": 1.3750027957295174}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11234.json
new file mode 100644
index 00000000000..6651417af9e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11234.json
@@ -0,0 +1 @@
+{"ALIMTA": 4.528023227796149, "AMIKACIN": 9.81378396551248, "ARAVA": 0.4755964857905826, "AZACITIDINE": 16.212030770111898, "BORTEZOMIB": 19.992138842365183, "BUDESONIDE": 2.7246974142268883, "BUSULFAN": 13.724922913484802, "CANCIDAS": 12.7876201157994, "CELLCEPT": 3.001961135661668, "CICLOSPORIN": 6.225457416309881, "CIMZIA": 1.424263089201372, "COMIRNATY": 0.0455108490796072, "CUBICIN": 8.457407179613572, "CYTARABINE": 9.32876394480068, "DARZALEX": 7.603985347213098, "DEXAMETHASONE": 2.2051839850569794, "EXJADE": 1.9983335085356373, "IBUPROFEN": 2.547494862212154, "INCIVO": 15.72155269759164, "JARDIANCE": 0.9748545495333598, "LEVOFLOXACIN": 2.4398103353176395, "METHOTREXATE": 4.96060426859391, "OPTIMARK": 2.573547081837788, "PEGASYS": 3.9824985413981504, "PEGINTERFERON": 4.902448837393527, "PEGINTRON": 1.6969093283072534, "RITUXIMAB": 4.757270683474585, "ROACTEMRA": 11.303652592899368, "SOLIRIS": 10.167827608917351, "SPIKEVAX": 0.0840688908511126, "STELARA": 0.9101225939213669, "TAMIFLU": 4.904903271744077, "TRACLEER": 2.4191864465016697, "null": 0.874806401440273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11235.json
new file mode 100644
index 00000000000..31fdcb6e134
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11235.json
@@ -0,0 +1 @@
+{"COSENTYX": 8.739475723841249, "PEGASYS": 7.225551169262287, "null": 0.5189197011632688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11236.json
new file mode 100644
index 00000000000..ae83c94e5ec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11236.json
@@ -0,0 +1 @@
+{"COSENTYX": 2.729073734551345, "CUBICIN": 22.673527040134186, "CYTARABINE": 6.9257335106474125, "ERBITUX": 64.7901255537391, "EYLEA": 13.171078332219569, "FYCOMPA": 30.773475985095885, "KEPPRA": 2.7913908790165465, "OMALIZUMAB": 21.076724178026428, "OPSUMIT": 8.820628223111724, "null": 1.186376069407772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11237.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11237.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11238.json
new file mode 100644
index 00000000000..4ebc1ee6fa6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11238.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 3.8793413088113753, "COMIRNATY": 0.0786782427657678, "CYMBALTA": 2.357746696925698, "GARDASIL": 6.79695711062048, "INFANRIX": 25.64488051212008, "KEPPRA": 7.003707098435617, "LACOSAMIDE": 9.848477393531736, "LANTUS": 1.0734137306881155, "LEVETIRACETAM": 4.781824550238014, "MMRVAXPRO": 9.926845169763938, "NIMENRIX": 11.444135577137825, "PEGINTRON": 2.589372448623031, "PREVENAR": 17.559643324297365, "SPIKEVAX": 0.2381565922048242, "TAMIFLU": 3.7913434651412032, "TOZINAMERAN": 0.3836542367034204, "VAXZEVRIA": 0.1300920418404824, "VIMPAT": 8.219892698013998, "ZYPREXA": 2.5069869789393464, "null": 2.291816685560467}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11239.json
new file mode 100644
index 00000000000..2219d534316
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11239.json
@@ -0,0 +1 @@
+{"INSULIN": 17.346301075210526, "JARDIANCE": 7.05586513463335, "null": 1.171974090748933}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1124.json
index 45468990827..fab5ca81e48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1124.json
@@ -1 +1 @@
-{"FENTANYL": 8.627357701117285, "MIDAZOLAM": 23.64965313822041, "null": 4.970459086487663}
\ No newline at end of file
+{"null": 1.22211340837723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11240.json
new file mode 100644
index 00000000000..89bd99d3f8d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11240.json
@@ -0,0 +1 @@
+{"JARDIANCE": 107.1579496295601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11241.json
new file mode 100644
index 00000000000..85df4787943
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11241.json
@@ -0,0 +1 @@
+{"OPTIMARK": 27.675873345745696, "VAXZEVRIA": 0.3415435043690918, "null": 0.6051628966471101}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11242.json
new file mode 100644
index 00000000000..a47275521fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11242.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.3618785553841994, "ANAKINRA": 1.583811717942726, "ASPARAGINASE": 1.1481669418568288, "AUBAGIO": 0.5530822755698398, "AVASTIN": 0.6531612577054008, "BRIVARACETAM": 79.90432061527258, "BRIVIACT": 23.69646905937574, "BUCCOLAM": 66.22376736825215, "BUSULFAN": 1.7827728875197546, "CANNABIDIOL": 11.094669733373134, "CARBIDOPA": 4.056015837522272, "CELLCEPT": 0.6209309564442146, "CHAMPIX": 0.2985313372857198, "CICLOSPORIN": 1.7033489823715735, "CLOPIDOGREL": 0.4936244275081171, "COMIRNATY": 0.1159342797510601, "CUBICIN": 2.0710652700024363, "CYMBALTA": 0.3367354985280079, "CYTARABINE": 0.5661339790556772, "DEXAMETHASONE": 3.2836963107891437, "EFIENT": 7.218294834511043, "ELIQUIS": 0.1677494608404066, "FAMPRIDINE": 12.605258572806523, "FAMPYRA": 9.804433619133746, "FENTANYL": 1.5718151996523786, "FYCOMPA": 26.01142895891065, "GARDASIL": 0.1746273894470254, "HUMAN": 3.737681102618512, "IBUPROFEN": 1.182871478094182, "INOVELON": 67.63086970948213, "KEPPRA": 32.68913848769505, "KEYTRUDA": 0.3741397816252878, "KYMRIAH": 1.416007329925252, "LACOSAMIDE": 122.35488654171624, "LEVETIRACETAM": 60.64410459081636, "LEVOFLOXACIN": 0.9803911652294128, "LYRICA": 0.5447447567329569, "MEKINIST": 0.7298266692562888, "MIDAZOLAM": 15.098614578229393, "MMRVAXPRO": 1.3553591866898165, "NIMENRIX": 0.982795328068778, "OLANZAPINE": 0.4707467046101332, "SPIKEVAX": 0.1296084916647762, "SUTENT": 0.1013141711841831, "TAMIFLU": 1.3755704167026124, "TOZINAMERAN": 0.4164037059971068, "VAXZEVRIA": 0.0972754171904139, "VIGABATRIN": 22.59161791463593, "VIMPAT": 22.31444620132796, "YESCARTA": 2.47426321594554, "ZYPREXA": 1.0827427104250489, "null": 1.5557203257259211}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11243.json
new file mode 100644
index 00000000000..19a93647747
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11243.json
@@ -0,0 +1 @@
+{"AIMOVIG": 61.6685289846343, "COMIRNATY": 1.4425570308140243, "VAXZEVRIA": 0.919098588557304, "null": 0.316676073089126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11244.json
new file mode 100644
index 00000000000..b52c13eecd0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11244.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 32.99114859274415, "null": 0.5834757734062404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11245.json
new file mode 100644
index 00000000000..627559f54dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11245.json
@@ -0,0 +1 @@
+{"AFINITOR": 10.768433371076965, "KAFTRIO": 66.7912255310647, "null": 1.9163906763345877}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11246.json
new file mode 100644
index 00000000000..ab0a3703095
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11246.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 24.30221743950744, "CICLOSPORIN": 12.289841291767, "DARZALEX": 53.7192731154701, "EXJADE": 52.6131199819559, "FAMPYRA": 33.71627927058602, "ICLUSIG": 80.01820927072826, "SPRYCEL": 26.56070785679696, "null": 0.5313385048612338}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11247.json
new file mode 100644
index 00000000000..c33f0012b5c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11247.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 8.495364503741394, "COMIRNATY": 0.4940463690261871, "ELIQUIS": 1.7840917751954628, "ENTYVIO": 8.545992426778799, "HUMIRA": 11.830584861422118, "OLANZAPINE": 5.311958906274488, "STELARA": 7.634202743584342, "TASIGNA": 11.208972007106675, "null": 0.5695992390269339}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11248.json
new file mode 100644
index 00000000000..568ee8018b8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11248.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 263.0032296998307, "ASPARAGINASE": 18.551315214788676, "AZACITIDINE": 33.18064330827153, "BEDAQUILINE": 29.902730725323096, "BUDESONIDE": 27.490492240107876, "BUSULFAN": 11.470870940333985, "CASPOFUNGIN": 150.69390469640794, "CICLOSPORIN": 3.4088863151157263, "CYTARABINE": 33.09178063487313, "LEVOFLOXACIN": 6.037602571048399, "ORKAMBI": 40.120419749451166, "null": 0.481380868746629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11249.json
new file mode 100644
index 00000000000..f5db46baa04
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11249.json
@@ -0,0 +1 @@
+{"null": 0.3890390994224157}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1125.json
index 1d6f0248069..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1125.json
@@ -1 +1 @@
-{"ALISKIREN": 76.07040974156008, "APROVEL": 4.672128060778976, "COAPROVEL": 6.263666661721709, "EXFORGE": 77.81979819753562, "FORXIGA": 1.5886363452678562, "IRBESARTAN": 10.563412562667695, "MICARDIS": 14.111349640701574, "RASILEZ": 110.24126918567978, "TEKTURNA": 143.43369787291007, "TELMISARTAN": 42.25598979425666, "VALSARTAN": 39.216790828152185, "null": 3.7565980554356257}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11250.json
new file mode 100644
index 00000000000..6123db8b86a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11250.json
@@ -0,0 +1 @@
+{"null": 0.7237271814845543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11251.json
new file mode 100644
index 00000000000..2c704fcf2d2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11251.json
@@ -0,0 +1 @@
+{"PLAVIX": 29.016339823534345, "null": 1.5814979032827292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11252.json
new file mode 100644
index 00000000000..07956106b96
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11252.json
@@ -0,0 +1 @@
+{"ANAKINRA": 13.3853097038767, "APIXABAN": 1.1830003157860902, "AVAMYS": 11.590201927682855, "AVANDAMET": 73.18778338968191, "AVANDIA": 76.16923964738442, "BYETTA": 6.044070256644217, "CELECOXIB": 7.906886363784955, "CIMZIA": 0.5521471537286465, "CLOPIDOGREL": 2.9999973626749927, "COMIRNATY": 0.0531403849701343, "CYMBALTA": 0.6369655100002061, "ELIQUIS": 3.537710937426002, "ENTRESTO": 1.3297527623286096, "HIZENTRA": 5.31880430611129, "HUMALOG": 1.3765154218455795, "INCRUSE": 6.058443078894984, "JANUMET": 4.66053381373437, "JANUVIA": 8.122769349342567, "JARDIANCE": 1.3339066375368407, "LANTUS": 4.091601815693234, "LEVEMIR": 2.959431759790387, "MEPOLIZUMAB": 2.5496069484941244, "OPSUMIT": 2.8124629201239144, "PLAVIX": 12.497315127215227, "RANOLAZINE": 95.27640926373576, "SPIKEVAX": 0.0952831935911853, "STELARA": 0.909239432368839, "TRACLEER": 1.752413160794044, "TRELEGY": 9.641572447898705, "VELTASSA": 5.932678121856803, "VOTRIENT": 1.153720657217225, "XTANDI": 4.0106960763241775, "ZOSTAVAX": 2.296816382860324, "null": 0.8010584793753278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11253.json
new file mode 100644
index 00000000000..b6f8879cb91
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11253.json
@@ -0,0 +1 @@
+{"AVAMYS": 12.708036874652258, "CARBIDOPA": 65.4535070949904, "FENTANYL": 7.881632216937925, "LEVODOPA": 185.73751418975763, "SIFROL": 174.20719820759956, "STALEVO": 36.10581657759274, "null": 2.144336307782556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11254.json
new file mode 100644
index 00000000000..de33cf8e420
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11254.json
@@ -0,0 +1 @@
+{"null": 1.2678387061803291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11255.json
new file mode 100644
index 00000000000..f8ab00f07d8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11255.json
@@ -0,0 +1 @@
+{"AIMOVIG": 82.92427575522919, "FORSTEO": 6.404162111241828, "TRUVADA": 2.4495776499485835, "null": 0.697324136236598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11256.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11256.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11257.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11257.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11258.json
new file mode 100644
index 00000000000..881b6740245
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11258.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 60.3312778045393, "AZATHIOPRINE": 26.865207634171227, "ENTYVIO": 34.89743381183963, "HUMIRA": 31.50258602108472, "null": 0.2446716832710278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11259.json
new file mode 100644
index 00000000000..981ca8f9f99
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11259.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 12.635004786601137, "CELLCEPT": 19.028497432686777, "CICLOSPORIN": 19.82299526644793, "DEXAMETHASONE": 7.575629678333313, "DUPILUMAB": 586.56256011252, "OPDIVO": 7.85353687757981, "null": 0.942107518397744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1126.json
index 029993571c9..de3edffe271 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1126.json
@@ -1 +1 @@
-{"ACE": 3.3731949253441567, "ACLASTA": 1.6467268092325318, "AFINITOR": 2.0400831043519703, "AGALSIDASE": 6.42932868638543, "AIMOVIG": 1.2925318258022491, "ALISKIREN": 6.847405359181285, "ANTIHYPERTENSIVES": 5.199049149517635, "APROVEL": 4.769974440508845, "AUBAGIO": 1.446841569611336, "AVASTIN": 1.0238570949890382, "AVELUMAB": 1.0623118497879158, "AXITINIB": 2.2695254341026607, "AZOPT": 1.913020498477437, "BAVENCIO": 2.639365297454336, "BELIMUMAB": 3.942898051325023, "BETMIGA": 13.212802497626155, "BEVACIZUMAB": 1.1550275171260953, "BONVIVA": 1.0632796177636266, "BRINTELLIX": 1.1429552265474383, "CABOMETYX": 3.6499840314068215, "CALCIUM": 10.683176443952298, "CAPRELSA": 2.573533810819655, "CELECOXIB": 1.9103942904459077, "CHAMPIX": 1.3846878221526893, "CICLOSPORIN": 1.3151918933696332, "COAPROVEL": 3.808341138846553, "COMIRNATY": 1.0923295514713027, "COPALIA": 7.09155877008656, "CYMBALTA": 2.0009052009017654, "DAFIRO": 5.248971730957916, "DARZALEX": 1.7136681081721743, "DULAGLUTIDE": 1.318283108903237, "EDARBI": 29.207727799982347, "ENTRESTO": 1.050097593009401, "ENZALUTAMIDE": 1.0215417719070623, "ERENUMAB": 2.927533943060538, "ERLEADA": 1.286263386841699, "ESMYA": 1.0034394787104974, "EVISTA": 1.1066228838656476, "EVUSHELD": 2.09635426668533, "EXELON": 1.158911282645699, "EXFORGE": 12.225226551223868, "FLEBOGAMMA": 4.145427132656208, "FLUTICASONE": 1.1641754854494073, "FORSTEO": 2.1899074140895967, "FORXIGA": 1.3460673606801603, "FOTIVDA": 5.482675094782659, "GALAFOLD": 1.0555991978677426, "GALVUS": 1.7807632479852702, "GAVRETO": 2.729743293333726, "GAZYVARO": 1.3624236664106966, "GILENYA": 1.259075929779481, "GLIBENCLAMIDE": 1.0387804424086495, "HUMAN": 1.3835068168932811, "HYDROCHLOROTHIAZIDE": 4.319102189370401, "ICLUSIG": 1.4918258769967838, "ILARIS": 3.490262830807408, "INFLECTRA": 2.451239420858565, "INFLIXIMAB": 1.4353225141238624, "INLYTA": 5.947618298117494, "IRBESARTAN": 2.8352459456034658, "IVABRADINE": 1.1860057252750815, "KARVEA": 7.1385618572660565, "KARVEZIDE": 2.973145483302433, "KETOCONAZOLE": 2.813878334244332, "KIOVIG": 3.046015383938677, "LEFLUNOMIDE": 1.073237746661643, "LENVIMA": 3.8734521482711983, "LUPKYNIS": 2.42346314653226, "MEMANTINE": 1.4337484194551342, "MEPOLIZUMAB": 3.0013009219955125, "METHOTREXATE": 1.1789579217016992, "MICARDIS": 6.917219605308899, "MICARDISPLUS": 2.8455345326658343, "MIRABEGRON": 6.980449298273246, "MIRCERA": 3.4570393743604626, "MOVYMIA": 2.014197915241601, "MVASI": 1.3350217579413672, "NAGLAZYME": 1.089141795853847, "NEVANAC": 3.242306607788607, "NEXAVAR": 2.334930103542417, "NUCALA": 1.06027314855381, "OCTREOTIDE": 1.6862448427114562, "OMALIZUMAB": 4.021068855045272, "ORENCIA": 1.6015862762788728, "OTHER": 3.1218108046572746, "PANTOPRAZOLE": 1.3722274284540978, "PASIREOTIDE": 9.312455956084708, "PAZOPANIB": 2.1557975006304075, "PERJETA": 2.3280484829120605, "PRIALT": 2.0026373772275017, "PRITOR": 4.776165062191402, "PRIVIGEN": 2.722239161204472, "PROLIA": 5.105591455729214, "PROPRANOLOL": 1.3502759201197918, "PROTELOS": 2.3575046156835926, "RASILEZ": 12.384733768824791, "RELVAR": 1.0994080743790078, "RITUXIMAB": 1.920578908129574, "SILDENAFIL": 1.040545663065205, "SOLIRIS": 1.1691820722117725, "SOMAVERT": 2.686796936401434, "SPIRONOLACTONE": 1.0009727869791925, "STIVARGA": 2.583158091345232, "SUTENT": 3.850220793460661, "TADALAFIL": 2.6807718043003, "TEKTURNA": 8.85084234412658, "TELMISARTAN": 3.3168886646528093, "TERIFLUNOMIDE": 1.2283341409520672, "TRULICITY": 1.3493127423744002, "TWYNSTA": 2.884530671584097, "VALSARTAN": 5.348806419371984, "VIAGRA": 1.3861025499541115, "VOTRIENT": 3.3709184457055352, "XOLAIR": 1.9431575878565484, "XTANDI": 1.6597049716512735, "XYREM": 2.8783708844042546, "ZEJULA": 4.591996010431943, "ZYPADHERA": 3.8597944659133, "null": 1.4458331292588262}
\ No newline at end of file
+{"BONVIVA": 957.3265170684526, "EVENITY": 213.41435445724005, "null": 0.3717904058578015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11260.json
new file mode 100644
index 00000000000..f39453df4bb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11260.json
@@ -0,0 +1 @@
+{"null": 0.6470135058058539}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11261.json
new file mode 100644
index 00000000000..46cf2de5c00
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11261.json
@@ -0,0 +1 @@
+{"HYDROCORTISONE": 332.72717613374505, "PROTOPIC": 422.5084700847652, "null": 2.599699914360352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11262.json
new file mode 100644
index 00000000000..eb2a43dcd7a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11262.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.5396546352869211, "null": 0.7935073517165068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11263.json
new file mode 100644
index 00000000000..ee757d705d0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11263.json
@@ -0,0 +1 @@
+{"1": 67.16782399335501, "ABACAVIR": 0.2075955316911376, "ABILIFY": 0.3257532516286837, "ACTOS": 1.9927862747548877, "ACTRAPID": 4.597069127557772, "ADENURIC": 2.025770986385282, "AERIUS": 1.8277037438760837, "ALIMTA": 1.7591816061815493, "ALL": 4.412685173382017, "AMIKACIN": 3.107716393098529, "APIDRA": 0.778863995075153, "APROVEL": 1.910452102736917, "ARANESP": 0.288273678027379, "ARAVA": 0.1959240470643388, "ARIPIPRAZOLE": 0.3281321670058704, "ATRIPLA": 0.1035685532619122, "AUBAGIO": 0.3149028792285487, "AZATHIOPRINE": 0.4321707454452766, "BEVACIZUMAB": 0.476086600779937, "BIKTARVY": 1.6966404464377736, "BRINTELLIX": 0.4847658113966939, "BUDESONIDE": 0.2615806989882019, "CABOMETYX": 0.7369163345220717, "CANCIDAS": 6.4233581175141, "CASPOFUNGIN": 1.3237066770891626, "CHAMPIX": 0.7368260001015806, "CICLOSPORIN": 0.1655066219725866, "CIMZIA": 0.0784113405867828, "CLOPIDOGREL": 0.7179164251424078, "COMBIVIR": 4.075784392133059, "COMIRNATY": 0.0203550268626378, "COTELLIC": 10.40663698851975, "CUBICIN": 5.294157804415451, "CYMBALTA": 0.7220211992070051, "CYTARABINE": 0.8186855709858606, "DEXAMETHASONE": 1.4455298875385487, "DOCETAXEL": 0.7639986264075461, "EFAVIRENZ": 1.5449792102560806, "ELIQUIS": 0.2304939269580555, "EMEND": 4.661525762191892, "EMTRICITABINE": 1.7243482076413978, "EPIVIR": 1.2612078047504378, "ERLEADA": 9.09402242960422, "ESOMEPRAZOLE": 1.326727732432501, "EXFORGE": 0.3402590198181053, "EXJADE": 0.3456062166346049, "FEBUXOSTAT": 11.081747040054172, "FENTANYL": 1.867559915306472, "FORTIMEL": 147.1076537627112, "HALAVEN": 2.142005525052563, "HUMIRA": 0.4362554781308104, "HYDROCHLOROTHIAZIDE": 5.435724155453702, "HYDROCORTISONE": 0.9646458005301728, "IBUPROFEN": 7.218937774182322, "INCIVO": 1.159691580507321, "INSUMAN": 6.057229131990138, "INVIRASE": 5.18114460238931, "IPILIMUMAB": 0.8645539673106196, "IRBESARTAN": 0.7180064030084049, "IRESSA": 0.7281967719900442, "ISENTRESS": 1.6131274702564222, "JANUMET": 0.632513008056811, "JANUVIA": 0.8423542936217914, "JARDIANCE": 0.143899917431396, "KALETRA": 1.514511301407418, "KEPPRA": 5.126559747459017, "KEYTRUDA": 3.947125338065236, "KONTRASTMITTEL": 241.22462686802143, "LACOSAMIDE": 3.641457700222728, "LAMIVUDINE": 6.610783681243444, "LEVETIRACETAM": 3.699917652129902, "LEVOFLOXACIN": 4.658805746753255, "LYRICA": 1.1412844326654372, "MABTHERA": 0.9690834647216184, "METHOTREXATE": 0.7606514432539707, "MICARDIS": 2.0260853359400395, "MIRCERA": 2.059709091711614, "NEVIRAPINE": 86.68310203512402, "NEXAVAR": 2.570901837935917, "NOVONORM": 2.516191609823207, "OLANZAPINE": 0.2236714358358584, "OPDIVO": 2.238393996782843, "OSELTAMIVIR": 4.290335738141466, "PANTOPRAZOLE": 1.324012172383705, "PEGASYS": 1.1537215264462763, "PEGINTERFERON": 2.3941538326788865, "PEGINTRON": 0.904585553778138, "PEMBROLIZUMAB": 2.870500766998736, "PLAVIX": 1.3741053260700455, "PROTELOS": 2.2426525988984025, "RADIATION": 5.863591174985291, "REVLIMID": 1.7646000729718512, "RIBAVIRIN": 1.027795690614819, "RINVOQ": 0.3406593854314653, "RISPERIDONE": 1.937517840917626, "RITUXIMAB": 0.261901440794697, "SIFROL": 2.3956492362203927, "SIMPONI": 0.1332299443115863, "SORAFENIB": 4.156051349482739, "SPIKEVAX": 0.0356643164746965, "SPIRONOLACTONE": 12.222780166169269, "STIVARGA": 2.54660755667294, "SUTENT": 0.1585943905814492, "TAGRISSO": 1.598085770845456, "TAMIFLU": 8.785857829085096, "TELBIVUDINE": 235.45859548184885, "TEMODAL": 7.507667580523036, "THALIDOMIDE": 1.995580443552428, "TORISEL": 1.3524630683071444, "TOZINAMERAN": 0.0705421719809457, "TRUVADA": 0.1319125837139882, "UNKNOWN": 6.515991760576148, "VAXZEVRIA": 0.0239565537410817, "VFEND": 2.270270184655644, "VIMPAT": 2.080520459582734, "VIRAMUNE": 69.85535057626883, "VORICONAZOLE": 1.469764241195335, "XTANDI": 0.1795056430143736, "ZELBORAF": 3.0037555079773863, "ZONISAMIDE": 7.613532078378639, "ZYPREXA": 0.4260533873531316, "null": 3.637008195314463}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11264.json
new file mode 100644
index 00000000000..a3eafced072
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11264.json
@@ -0,0 +1 @@
+{"NPLATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11265.json
new file mode 100644
index 00000000000..859d325a465
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11265.json
@@ -0,0 +1 @@
+{"null": 2.688163851193987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11266.json
new file mode 100644
index 00000000000..8feb78efd4f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11266.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 2.6034749516263456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11267.json
new file mode 100644
index 00000000000..3caf61bab9a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11267.json
@@ -0,0 +1 @@
+{"null": 0.8979764095138555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11268.json
new file mode 100644
index 00000000000..601c6a5bcbb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11268.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.5290344676170151, "null": 0.9168522116103828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11269.json
new file mode 100644
index 00000000000..edd34153d5b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11269.json
@@ -0,0 +1 @@
+{"ANAKINRA": 38.1235868330441, "CICLOSPORIN": 6.334033547837323, "COMIRNATY": 0.9124320042262704, "ENBREL": 6.950186298841065, "GARDASIL": 2.8314761302845426, "METHOTREXATE": 11.207664690089864, "SPIKEVAX": 0.379643366584092, "TOZINAMERAN": 2.2060771190084827, "VAXZEVRIA": 0.906960492032998, "null": 0.6613200069131948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1127.json
index 1a07f921480..e0b872f0494 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1127.json
@@ -1 +1 @@
-{"AIMOVIG": 9.192329819907563, "COVID19": 4.830527799155113, "ELIQUIS": 1.898667918823974, "ERENUMAB": 88.48518702527767, "VAXZEVRIA": 2.0452379851995324}
\ No newline at end of file
+{"BONVIVA": 1262.5054649581284, "EVENITY": 224.31030932772043}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11270.json
new file mode 100644
index 00000000000..68cef38c27f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11270.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.508943616746021, "ATOSIBAN": 98.94594387338395, "BUPRENORPHINE": 4.06939722441936, "CIMZIA": 1.1240613311582557, "COMBIVIR": 57.30267273245861, "COMIRNATY": 0.2139318401099699, "CYTARABINE": 2.4237329318908407, "EFAVIRENZ": 25.428185495863296, "ENTYVIO": 2.7755263595335102, "HUMALOG": 1.1230780760623489, "ISENTRESS": 28.617664580261952, "KALETRA": 20.99853293378451, "KEPPRA": 2.35744470954302, "LAMIVUDINE": 19.76986616190751, "LEVEMIR": 4.948490574036661, "LEVETIRACETAM": 5.663763222584945, "MIDAZOLAM": 8.01891289813498, "NEVIRAPINE": 35.25322250807682, "NORVIR": 18.583614530309685, "OSELTAMIVIR": 70.6872639638126, "REMICADE": 9.257644931739534, "SPIKEVAX": 0.1465636893285555, "SUBOXONE": 6.489291769133408, "TAMIFLU": 3.74995180581302, "TOZINAMERAN": 0.3498344187934417, "XOLAIR": 2.539588048741906, "null": 1.6866836926797344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11271.json
new file mode 100644
index 00000000000..a1545f98775
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11271.json
@@ -0,0 +1 @@
+{"REVESTIVE": 3463.132671985337, "null": 1.1181456072434313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11272.json
new file mode 100644
index 00000000000..7709c2a7a14
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11272.json
@@ -0,0 +1 @@
+{"null": 0.5623079634166885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11273.json
new file mode 100644
index 00000000000..ace0291cabf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11273.json
@@ -0,0 +1 @@
+{"JARDIANCE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11274.json
new file mode 100644
index 00000000000..7ce4aded616
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11274.json
@@ -0,0 +1 @@
+{"null": 0.7507753524980778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11275.json
new file mode 100644
index 00000000000..6be5580992a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11275.json
@@ -0,0 +1 @@
+{"null": 2.5976518060301648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11276.json
new file mode 100644
index 00000000000..1e574b6d846
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11276.json
@@ -0,0 +1 @@
+{"AVASTIN": 52.91942055047259, "BEVACIZUMAB": 37.69295412010191, "ELIQUIS": 9.087246224370164, "STIVARGA": 53.40505685373885, "null": 0.7283760728637136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11277.json
new file mode 100644
index 00000000000..7c0a93f1006
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11277.json
@@ -0,0 +1 @@
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11278.json
new file mode 100644
index 00000000000..f799729472b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11278.json
@@ -0,0 +1 @@
+{"null": 0.7267193828409113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11279.json
new file mode 100644
index 00000000000..1fe069abbf5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11279.json
@@ -0,0 +1 @@
+{"null": 2.2258157578933897}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1128.json
index cabc1e745e1..378e7a57e2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1128.json
@@ -1 +1 @@
-{"null": 2.992924724076415}
\ No newline at end of file
+{"CARFILZOMIB": 125.2637112436148, "COMIRNATY": 0.1400501420860362, "KYPROLIS": 172.1886774658512, "SOLIRIS": 216.2035817871704, "VAXZEVRIA": 0.3716672779067096, "null": 0.2231168193537865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11280.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11280.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11281.json
new file mode 100644
index 00000000000..6c7f15fc458
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11281.json
@@ -0,0 +1 @@
+{"null": 1.0464775269638364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11282.json
new file mode 100644
index 00000000000..4b093f92c4b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11282.json
@@ -0,0 +1 @@
+{"REVESTIVE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11283.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11283.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11284.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11284.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11285.json
new file mode 100644
index 00000000000..b7a2ebdac24
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11285.json
@@ -0,0 +1 @@
+{"null": 1.913393433494604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11286.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11286.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11287.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11287.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11288.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11288.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11289.json
new file mode 100644
index 00000000000..314e55022cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11289.json
@@ -0,0 +1 @@
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1129.json
index 61f3aa553f4..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1129.json
@@ -1 +1 @@
-{"null": 1.280142941968354}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11290.json
new file mode 100644
index 00000000000..50b34722de6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11290.json
@@ -0,0 +1 @@
+{"BYETTA": 30.33225054146053, "null": 1.141091914569382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11291.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11291.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11292.json
new file mode 100644
index 00000000000..bd00e3b521a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11292.json
@@ -0,0 +1 @@
+{"null": 1.5494092413988425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11293.json
new file mode 100644
index 00000000000..ba9291b2a78
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11293.json
@@ -0,0 +1 @@
+{"ABATACEPT": 6.807118034592655, "ABRAXANE": 5.317968489156255, "ADALIMUMAB": 2.211444489873832, "AFINITOR": 30.12714462260718, "AFLIBERCEPT": 8.93862400427411, "AIMOVIG": 0.348239032426698, "ALEMTUZUMAB": 0.4786513304763534, "ALIMTA": 3.789363909776583, "ANAKINRA": 3.188435502399234, "APREMILAST": 1.6886669792325653, "APREPITANT": 0.6677452486699035, "ARAVA": 2.098312542233166, "ASPARAGINASE": 3.141583824361632, "ATEZOLIZUMAB": 2.09132186730812, "AUBAGIO": 0.3611768649560992, "AVASTIN": 5.86367331622579, "AVELUMAB": 2.1646869755117897, "AXITINIB": 5.028639021466682, "AZACITIDINE": 1.1255604120710558, "AZATHIOPRINE": 0.9978078269644068, "BAVENCIO": 5.269570493226762, "BENLYSTA": 1.1995496261599796, "BEVACIZUMAB": 3.552382330183842, "BOCEPREVIR": 2.082148023449525, "BONVIVA": 0.7695096914964998, "BORTEZOMIB": 0.6274352272755754, "BOSULIF": 1.2727776605566898, "BUDESONIDE": 0.1801587994092624, "BUSILVEX": 14.75385260905805, "BUSULFAN": 7.139853964495369, "CABOMETYX": 12.119383627469611, 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2.2701260953007023, "LYRICA": 0.1473874474719475, "MABTHERA": 1.7756033951442745, "MEKINIST": 0.7100689056833853, "MELPHALAN": 5.63676359675866, "MERCAPTOPURINE": 2.3012551960688348, "METFORMIN": 0.9325195219723128, "METHOTREXATE": 2.780952231321607, "MMRVAXPRO": 0.4308165718723987, "MYCOPHENOLATE": 0.5435272941252635, "NEULASTA": 0.709257430845148, "NEXAVAR": 4.845770834726587, "NIMENRIX": 0.2659066976373278, "NINLARO": 0.8120861581675068, "NOXAFIL": 0.7788624548482724, "NPLATE": 0.3752948234886052, "OFEV": 0.3288190779549133, "OPDIVO": 1.6956424793770577, "ORENCIA": 1.825305935805572, "PACLITAXEL": 1.023006428107888, "PANITUMUMAB": 14.775462739678083, "PAZOPANIB": 1.7092680977737222, "PEGASYS": 1.8111204491465305, "PEGFILGRASTIM": 2.6350230536707504, "PEGINTERFERON": 1.436549979782193, "PEGINTRON": 1.4949874138787649, "PEMBROLIZUMAB": 1.892753980526607, "PEMETREXED": 1.9675731400345404, "PIQRAY": 6.4326821372027245, "PLAVIX": 0.2590559887495622, "PROTELOS": 2.634610828716776, 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2.156881394561052, "VAXZEVRIA": 0.0808167358091253, "VECTIBIX": 17.432560332732237, "VOTRIENT": 3.571288332668986, "XELJANZ": 0.8529504337392383, "XELODA": 5.051706541413796, "XTANDI": 0.1575023742396699, "ZELBORAF": 1.53447209008042, "ZOSTAVAX": 0.1402686838080826, "null": 0.7683653050998497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11294.json
new file mode 100644
index 00000000000..23e3e05a71c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11294.json
@@ -0,0 +1 @@
+{"null": 0.5450858387780103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11295.json
new file mode 100644
index 00000000000..bbe30e88660
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11295.json
@@ -0,0 +1 @@
+{"null": 1.684094227665661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11296.json
new file mode 100644
index 00000000000..0e7d8a4cb83
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11296.json
@@ -0,0 +1 @@
+{"null": 0.6572227330518101}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11297.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11297.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11298.json
new file mode 100644
index 00000000000..778f4aad1f0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11298.json
@@ -0,0 +1 @@
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11299.json
new file mode 100644
index 00000000000..f8a8bc6e1ac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11299.json
@@ -0,0 +1 @@
+{"BUPIVACAINE": 72.01150746244191, "CARIPRAZINE": 137.18559849467545, "COMIRNATY": 0.2958279538777022, "GARDASIL": 0.941731334083574, "INFANRIX": 22.238659704767255, "KALETRA": 5.17438382989372, "KEPPRA": 1.679258197828656, "KEYTRUDA": 1.3825922461669304, "MMRVAXPRO": 6.805512796656956, "SPIKEVAX": 0.273265888793933, "TAMIFLU": 4.624468574170573, "TOZINAMERAN": 0.447134906929361, "VAXZEVRIA": 0.1732838648117758, "ZOSTAVAX": 1.3549763722190142, "null": 3.071820094901515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/113.json
index 9c8b6e48f18..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/113.json
@@ -1 +1 @@
-{"ZOMETA": 455.2063790686895}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1130.json
index d2d699059a0..fbfaa39bc26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1130.json
@@ -1 +1 @@
-{"null": 1.7905178883577637}
\ No newline at end of file
+{"ABACAVIR": 6.40049620029478, "AMIKACIN": 45.750479287930375, "ATAZANAVIR": 32.03969101856278, "CELLCEPT": 7.581030826744377, "CICLOSPORIN": 7.687795289364942, "DESCOVY": 59.78808350513631, "ISENTRESS": 22.60640176633081, "JAKAVI": 13.560363430836237, "METHOTREXATE": 5.044969926343649, "SIMPONI": 9.338197386498036, "STELARA": 2.708828439774494, "null": 0.8402645454518812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11300.json
new file mode 100644
index 00000000000..d3f6fdbaceb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11300.json
@@ -0,0 +1 @@
+{"null": 7.873021516387272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11301.json
new file mode 100644
index 00000000000..3f3ead18445
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11301.json
@@ -0,0 +1 @@
+{"null": 0.8542544306861334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11302.json
new file mode 100644
index 00000000000..e8ce43fc13c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11302.json
@@ -0,0 +1 @@
+{"null": 2.092924543033899}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11303.json
new file mode 100644
index 00000000000..1a933e74ee4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11303.json
@@ -0,0 +1 @@
+{"null": 3.310303857497181}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11304.json
new file mode 100644
index 00000000000..eb406a1c473
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11304.json
@@ -0,0 +1 @@
+{"BUSULFAN": 97.44175660164385, "CYTARABINE": 34.90311658194775, "METHOTREXATE": 11.68117596623713, "null": 0.4128951122504577}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11305.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11305.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11306.json
new file mode 100644
index 00000000000..79367f7a4c5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11306.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.6668245422022907, "AMIKACIN": 17.30427004045918, "ARIPIPRAZOLE": 4.486400403880586, "CASPOFUNGIN": 29.846691693096474, "CICLOSPORIN": 4.509214905666242, "CIMZIA": 2.171793439958505, "COMIRNATY": 0.1464685353377479, "COSENTYX": 2.281724282651118, "DEXAMETHASONE": 3.1925055192795573, "EYLEA": 7.106243481482463, "GARDASIL": 1.765424541168829, "HIZENTRA": 9.908606405164807, "JARDIANCE": 2.1794144221908724, "PEGASYS": 1.0614371607593909, "PEGINTRON": 2.99569724684197, "SPIKEVAX": 0.0959183405237693, "STELARA": 4.857799790224413, "TOZINAMERAN": 0.2628838309588647, "XOLAIR": 2.333086403524534, "null": 0.894589319484733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11307.json
new file mode 100644
index 00000000000..32fa0d8e696
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11307.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 4.699214392210529, "COMIRNATY": 0.1270088502166537, "CYTARABINE": 24.48153756135591, "ROACTEMRA": 21.42853484533416, "null": 0.5811018828808119}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11308.json
new file mode 100644
index 00000000000..02957dd7701
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11308.json
@@ -0,0 +1 @@
+{"null": 0.8910504781680227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11309.json
new file mode 100644
index 00000000000..ba10852da69
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11309.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1257849762481898, "GARDASIL": 6.955982603534175, "null": 0.9749451806732612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1131.json
index 15b3193f952..d22ceaa04f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1131.json
@@ -1 +1 @@
-{"null": 1.0245925900438484}
\ No newline at end of file
+{"AMIKACIN": 534.8625835358554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11310.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11310.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11311.json
new file mode 100644
index 00000000000..2c91ba495d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11311.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.1325319985164776, "ABILIFY": 1.5424367748004533, "ACLASTA": 6.108713715741348, "ADALIMUMAB": 0.914890509339289, "ADEMPAS": 1.9666597945820896, "AFINITOR": 0.4865609123685223, "AIMOVIG": 7.348562417837919, "ALEMTUZUMAB": 1.11785636315724, "ANAKINRA": 0.6840401588556879, "APIDRA": 1.8704792105332109, "ARANESP": 14.697131111070831, "ARAVA": 0.6708577662622383, "ARIPIPRAZOLE": 1.0355787144110815, "ATRIPLA": 0.2051008563628902, "AUBAGIO": 4.007745544065408, "AVANDIA": 0.5033141558222352, "AVONEX": 5.4165163401991325, "BENLYSTA": 3.845896128641382, "BIKTARVY": 1.174335865534843, "BOSULIF": 2.7406052831799, "BOTULINUM": 3.511905346801957, "BRINTELLIX": 0.6142618169138626, "BRIVIACT": 1.663206287304493, "BUDESONIDE": 0.4824129563743343, "BUPRENORPHINE": 0.836243723885826, "BYDUREON": 1.720082150810981, "BYETTA": 2.175542803836019, "C1": 20.750398350407863, "CANNABIDIOL": 2.7654569226944017, "CAPECITABINE": 1.223416153497566, "CELLCEPT": 0.3483610430526715, "CHAMPIX": 3.944521303528497, "CICLOSPORIN": 0.382860540121492, "CIMZIA": 2.630433241704332, "CINRYZE": 6.568027563436781, "CLOPIDOGREL": 1.2091675286314394, "COMIRNATY": 0.3070881594351926, "COSENTYX": 2.981237339622082, "CYMBALTA": 1.2292782053476885, "DARBEPOETIN": 20.310307451906084, "DEXAMETHASONE": 0.4143370719265443, "ELIQUIS": 0.726966957292777, "ENBREL": 1.7166857390841666, "ENTRESTO": 0.4828961046292411, "ENTYVIO": 3.0568258787057005, "ESBRIET": 1.0683925843360336, "EXFORGE": 1.630385120592809, "FAMPYRA": 2.040098117159626, "FASENRA": 1.605425766414308, "FASLODEX": 0.6463123168317731, "FENTANYL": 0.3214825979435088, "FIRDAPSE": 1.6563577601963193, "FLUTICASONE": 11.490498786996463, "FORSTEO": 0.8816115615029382, "FORXIGA": 0.3790994411116884, "FULVESTRANT": 1.2061639304896197, "GARDASIL": 1.944713157190328, "GILENYA": 9.27220948299212, "HARVONI": 0.577840905389208, "HIZENTRA": 1.27407783407069, "HUMALOG": 4.736746683055314, "HUMIRA": 4.301117244529364, "HYDROCORTISONE": 0.6562256808418497, "I": 119.16129990853575, "IBRANCE": 2.671282907922408, "IBUPROFEN": 0.6230463910565037, "INCIVO": 0.7833036898801762, "INFLECTRA": 5.44121800290882, "INSULIN": 6.060129646316224, "JAKAVI": 0.3859413891598907, "JANUMET": 1.2291387648666563, "JANUVIA": 0.7421713992739878, "JARDIANCE": 0.4417941391681552, "KAFTRIO": 0.894502664117276, "KEPPRA": 1.6053750241935638, "KEYTRUDA": 0.1565324102407637, "LANTUS": 1.72816884984357, "LATUDA": 2.730203913937683, "LEFLUNOMIDE": 1.373562908973596, "LEMTRADA": 0.7308023008365884, "LEVEMIR": 1.2810039730240568, "LEVETIRACETAM": 0.4301610365498904, "LYRICA": 1.1373242409973932, "MAVENCLAD": 1.7501039708568784, "MEPOLIZUMAB": 4.566668863648776, "METHOTREXATE": 2.024514967997303, "NAGLAZYME": 1.1397446289223303, "NUCALA": 1.175146857512766, "OCRELIZUMAB": 0.7372568767820225, "OLANZAPINE": 0.4701026574383022, "OMALIZUMAB": 4.224527376749693, "OPSUMIT": 0.8380837051891827, "OPTIMARK": 1.857307982392227, "PANTOPRAZOLE": 0.6964848467529067, "PEGASYS": 0.5356755447908623, "PEGINTRON": 0.5409132996259146, "PLAVIX": 0.4935429981760366, "PLEGRIDY": 3.991988961682665, "PROPRANOLOL": 2.3835981458431625, "RASILEZ": 1.1022643251556912, "REMSIMA": 19.057788030558893, "REVATIO": 0.7777036920220292, "RINVOQ": 1.3249129622275886, "RITUXIMAB": 0.5198791924153557, "RUCONEST": 5.023775538339215, "SHINGRIX": 0.6170863173887002, "SILDENAFIL": 2.6215678972586574, "SIMPONI": 1.367178028153042, "SKYRIZI": 2.83542321950803, "SOLIRIS": 1.4621851442960312, "SOMATROPIN": 2.4625437485970263, "SPIKEVAX": 0.2393674406219288, "SPINRAZA": 0.8497427730689087, "STELARA": 1.5664856457418366, "SUBOXONE": 1.0968946031823523, "SUTENT": 0.1701516631858764, "TOUJEO": 2.5029855386445985, "TOVIAZ": 0.8668179170496819, "TOZINAMERAN": 0.929687381084636, "TRACLEER": 0.332678609574619, "TRELEGY": 0.3717319687308171, "TREMFYA": 1.0570813705137092, "TRULICITY": 1.4912090823450772, "TRUVADA": 0.1234719514190478, "VAXZEVRIA": 0.1941620469416906, "VIAGRA": 2.360335735435324, "VICTOZA": 0.6479571441379098, "VIMPAT": 1.3813468186777986, "XELJANZ": 4.405579955522297, "XOLAIR": 2.065344037271125, "XTANDI": 0.3411403262999554, "XYREM": 6.489671831261996, "ZOSTAVAX": 2.822543114277364, "ZYPREXA": 0.7970209120093543, "null": 1.154181164250888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11312.json
new file mode 100644
index 00000000000..cda4d72c950
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11312.json
@@ -0,0 +1 @@
+{"ARAVA": 4.35427156831642, "null": 0.6737987057420408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11313.json
new file mode 100644
index 00000000000..e301467ef8f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11313.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 2.486913848214246, "CARBIDOPA": 13.124366268631064, "COMIRNATY": 0.2861021368850591, "CYMBALTA": 0.4842793769804228, "DENOSUMAB": 22.053231000965635, "FENTANYL": 13.255410247235424, "HUMAN": 4.81380222952927, "KEYTRUDA": 3.0529286493478844, "LEVETIRACETAM": 1.4752944519727087, "MIDAZOLAM": 11.47784632786579, "SPIKEVAX": 0.1970216682198816, "SUFENTANIL": 34.463940685367675, "SUTENT": 0.3278304816115966, "TOZINAMERAN": 0.2161742876866948, "VAXZEVRIA": 0.0852619593708641, "VOTRIENT": 1.4137097762527495, "XELJANZ": 0.6509610629915948, "null": 2.745711764634106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11314.json
new file mode 100644
index 00000000000..c79ee6c13de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11314.json
@@ -0,0 +1 @@
+{"ATRIPLA": 12.024172685464016, "BONVIVA": 74.54364290886284, "CIMZIA": 6.887507223734114, "ELIQUIS": 2.8931976536729365, "ENBREL": 15.234041501215229, "EVENITY": 17.55122792646365, "EVISTA": 20.131744991307844, "LOPINAVIR": 37.802660426631626, "ROACTEMRA": 5.088977555543065, "STRIBILD": 8.399935519389151, "TRUVADA": 2.8758305028396043, "XELJANZ": 3.1722264340431803, "null": 0.5873468757405759}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11315.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11315.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11316.json
new file mode 100644
index 00000000000..edda05af31b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11316.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 45.12518794901735, "null": 0.8736672188562427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11317.json
new file mode 100644
index 00000000000..4fdabc08beb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11317.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1899183712985344, "ZOSTAVAX": 9.678586172446655, "null": 1.84746185267002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11318.json
new file mode 100644
index 00000000000..98bea50cae3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11318.json
@@ -0,0 +1 @@
+{"ARAVA": 1.056898300046652, "CLOPIDOGREL": 0.7941740020093805, "COMIRNATY": 0.6329875187375156, "DEXAMETHASONE": 3.2491920747160057, "FENTANYL": 3.087816057246131, "GARDASIL": 0.9781411436921258, "LEVOFLOXACIN": 1.6683080635954386, "PLAVIX": 0.890628600216515, "SPIKEVAX": 0.1238682384631187, "SYNAGIS": 9.228466856804358, "TOZINAMERAN": 1.0424944249538184, "VAXZEVRIA": 0.2015923744973599, "XOLAIR": 5.414520676846805, "null": 2.834779992312342}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11319.json
new file mode 100644
index 00000000000..c96757ddb6e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11319.json
@@ -0,0 +1 @@
+{"null": 1.2000579486555316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1132.json
index e9bce8b8ca9..7f01923be6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1132.json
@@ -1 +1 @@
-{"ACLASTA": 128.3011620091081, "ANAKINRA": 14.513795267847357, "ARAVA": 2.3735426771780355, "CLOPIDOGREL": 7.441582571895414, "ELIQUIS": 2.17246954803393, "ENTRESTO": 5.338238989462096, "ESOMEPRAZOLE": 20.35462290700057, "METHOTREXATE": 39.57823648112768, "MICARDIS": 19.63180176255119, "RITUXIMAB": 148.3243939568738, "SILDENAFIL": 18.298201427140228}
\ No newline at end of file
+{"AFINITOR": 6.170540963473899, "CIMZIA": 1.3938950404643975, "COMIRNATY": 0.355195157781217, "CYTARABINE": 3.7276568503251672, "ELIQUIS": 1.632813970261538, "HIZENTRA": 10.28141760509201, "HUMALOG": 1.3620539044118258, "PEGASYS": 2.232197470738288, "SIMPONI": 2.0899023310397293, "SPIKEVAX": 0.5259513599000029, "SUTENT": 0.7553752087270641, "TOZINAMERAN": 0.4605736503981093, "VAXZEVRIA": 0.1161530893797165, "XELJANZ": 1.8631225700395777, "XOLAIR": 3.3041485295367634, "null": 0.7879768923843363}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11320.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11320.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11321.json
new file mode 100644
index 00000000000..5b9ac772702
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11321.json
@@ -0,0 +1 @@
+{"INFLIXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11322.json
new file mode 100644
index 00000000000..64616cfaddc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11322.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": 52.43402123596537, "MYCOPHENOLATE": 65.07194970070154, "null": 0.5029513980237041}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11323.json
new file mode 100644
index 00000000000..222eb02dd04
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11323.json
@@ -0,0 +1 @@
+{"ABILIFY": 111.69325845879636, "null": 0.7640763093253202}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11324.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11324.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11325.json
new file mode 100644
index 00000000000..b0d54735332
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11325.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.7585123646326166, "ARIPIPRAZOLE": 1.4728940074270844, "CICLOSPORIN": 0.9569937157339464, "CLOPIDOGREL": 1.0113971252710192, "COMIRNATY": 0.2102331042532605, "CYMBALTA": 1.4927754486228737, "FENTANYL": 2.545391183522616, "IBUPROFEN": 3.9890129483102506, "JARDIANCE": 1.004956901272151, "KEPPRA": 3.6233374586348903, "LACOSAMIDE": 4.743530213663774, "LANTUS": 0.5724195953704341, "LEVETIRACETAM": 2.8858574826976136, "LEVOFLOXACIN": 1.376274690552439, "MIDAZOLAM": 3.6306018416540846, "OLANZAPINE": 3.6873634011450624, "SPIKEVAX": 0.1201181774887812, "VAXZEVRIA": 0.1885401961087529, "VFEND": 2.255989659425053, "ZYPADHERA": 10.97224510541739, "ZYPREXA": 4.414903719105964, "null": 3.721855633199768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11326.json
new file mode 100644
index 00000000000..a902f54af8f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11326.json
@@ -0,0 +1 @@
+{"DOCETAXEL": 9.677926406363946, "KEYTRUDA": 3.0472870298527583, "null": 2.9713736304935336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11327.json
new file mode 100644
index 00000000000..854a231aaba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11327.json
@@ -0,0 +1 @@
+{"null": 0.855331966490197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11328.json
new file mode 100644
index 00000000000..a5cf98642ab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11328.json
@@ -0,0 +1 @@
+{"null": 1.156213239031477}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11329.json
new file mode 100644
index 00000000000..3b0deb599be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11329.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 4.1143909919312645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1133.json
index 11587c9e153..238d1590924 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1133.json
@@ -1 +1 @@
-{"ADCIRCA": 18.167031387000517, "AFINITOR": 1.2582802386973917, "ANAKINRA": 6.417537827206794, "BRIDION": 6.363081158175907, "BUMETANIDE": 20.205542814212677, "CAPECITABINE": 3.3573072669339576, "CLOPIDOGREL": 2.1612754406515995, "DASATINIB": 20.77244648872229, "ENTRESTO": 47.24903908371801, "EXFORGE": 5.5890487212959865, "FENTANYL": 10.368423565883402, "INFLIXIMAB": 19.546202951258667, "IVABRADINE": 83.14769727377978, "JANUVIA": 3.072645256243865, "JARDIANCE": 1.866214170690208, "KEPPRA": 1.5733901994266946, "KYMRIAH": 5.956464603966593, "MEPOLIZUMAB": 2.070709567079417, "MIDAZOLAM": 9.454372172298322, "OPSUMIT": 1.7194422375167289, "PANTOPRAZOLE": 9.16132134477122, "PROPRANOLOL": 13.284823948958318, "RASILEZ": 6.780974278636445, "null": 1.8242334393152}
\ No newline at end of file
+{"COMIRNATY": 1.6811400035200934, "CYMBALTA": 2.392620617653582, "ELIQUIS": 1.5719853871106348, "EXJADE": 6.109512861854927, "GARDASIL": 1.6347843421313322, "HYDROCORTISONE": 7.789567972717974, "KEPPRA": 2.0739266354514805, "LANTUS": 0.9061143762329646, "SPIKEVAX": 1.0658487927746867, "TOZINAMERAN": 0.5167268256561098, "VAXZEVRIA": 0.4062063432731546, "XELJANZ": 1.1821978130497524, "null": 1.205921883866332}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11330.json
new file mode 100644
index 00000000000..fe9fb53e246
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11330.json
@@ -0,0 +1 @@
+{"LANTUS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11331.json
new file mode 100644
index 00000000000..c72d296e00e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11331.json
@@ -0,0 +1 @@
+{"null": 2.515532717243679}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11332.json
new file mode 100644
index 00000000000..f98727b5f2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11332.json
@@ -0,0 +1 @@
+{"null": 0.6150315419721749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11333.json
new file mode 100644
index 00000000000..1e05f0d7c70
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11333.json
@@ -0,0 +1 @@
+{"AIMOVIG": 0.5850855175180669, "APIXABAN": 6.917929117735066, "APROVEL": 2.666400284847539, "ARAVA": 0.0766243317824527, "ARIXTRA": 13.267803265070238, "AVASTIN": 1.5372119060448872, "BRILIQUE": 7.2144805444788975, "CARBIDOPA": 5.674528644206311, "CELLCEPT": 0.7138865158220432, "CHAMPIX": 0.5083879547742044, "CICLOSPORIN": 0.6537549700305235, "CLOPIDOGREL": 13.193818809458882, "COMIRNATY": 0.4612637435183952, "CYMBALTA": 0.3635590824657609, "DEXAMETHASONE": 0.7553487735026323, "DULOXETINE": 1.3188333949539517, "EFIENT": 16.704334966114562, "ELIQUIS": 13.090419466041924, "ENOXAPARIN": 3.860770312780645, "EVENITY": 7.950975202226571, "EYLEA": 1.090263313107186, "FENTANYL": 0.5571958585647767, "HARVONI": 4.102340497844847, "IBUPROFEN": 0.8732010312100055, "INTRONA": 4.523764780366626, "JAKAVI": 1.5498403274716048, "KEPPRA": 0.6360465021191275, "KEYTRUDA": 0.5918663254513282, "LIXIANA": 7.023625928807696, "NEXAVAR": 0.7854620657084693, "NOVOSEVEN": 5.5505605038922665, "NPLATE": 1.7140332723567264, "PEGASYS": 1.6407999048788695, "PEGINTRON": 3.3067832041759617, "PLAVIX": 12.192642401738244, "PRADAXA": 8.723218035085091, "REMICADE": 3.7503765050725537, "ROACTEMRA": 0.8475446667997579, "SILDENAFIL": 4.294623274069011, "SIMPONI": 0.7712427894041621, "SOLIRIS": 0.9098314231702266, "SPIKEVAX": 0.2612049079829866, "STELARA": 0.3535012839392118, "SUTENT": 0.424860620740929, "TICAGRELOR": 11.808347174243016, "TOZINAMERAN": 0.3216818679328557, "VAXZEVRIA": 0.4749283770313548, "VIAGRA": 1.176577487644421, "VOTRIENT": 1.2902169151342056, "XARELTO": 8.105009312477103, "ZYPREXA": 0.5157177265699019, "null": 1.2108848890311628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11334.json
new file mode 100644
index 00000000000..ffed2e44063
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11334.json
@@ -0,0 +1 @@
+{"null": 0.8953782293383834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11335.json
new file mode 100644
index 00000000000..595839adac3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11335.json
@@ -0,0 +1 @@
+{"ELIQUIS": 8.436553350079393, "null": 1.5092562331001285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11336.json
new file mode 100644
index 00000000000..14bc86b5513
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11336.json
@@ -0,0 +1 @@
+{"null": 1.564765446007211}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11337.json
new file mode 100644
index 00000000000..a05a1b10ec9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11337.json
@@ -0,0 +1 @@
+{"null": 1.678978955745374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11338.json
new file mode 100644
index 00000000000..1fa62ca5f61
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11338.json
@@ -0,0 +1 @@
+{"EVENITY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11339.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11339.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1134.json
index f7cd95fd44f..3bb40932587 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1134.json
@@ -1 +1 @@
-{"ABATACEPT": 1.9250216236036013, "ACLASTA": 12.809967703396197, "AFINITOR": 9.611864717547988, "BAVENCIO": 7.94399100849343, "BETMIGA": 7.600927591689569, "CABOMETYX": 1.000883541885609, "CELECOXIB": 3.245382052519473, "CHLORHEXIDINE": 1.4106478871293815, "CIMZIA": 1.0634280767001667, "CLOPIDOGREL": 1.701641811278033, "COSENTYX": 3.1590746901677287, "CYMBALTA": 4.311575855696602, "DULOXETINE": 2.02288362180228, "ENTRESTO": 3.821362865648435, "ERLEADA": 2.989071122070139, "ESOMEPRAZOLE": 4.59373021950755, "EVEROLIMUS": 4.777221955175985, "EXFORGE": 25.6653199803015, "EXJADE": 1.2220147324911448, "FENTANYL": 1.4466308679895528, "FLEBOGAMMA": 4.886957626310301, "ILARIS": 32.642047386628555, "INLYTA": 1.8649914584271836, "INSULIN": 2.192305886796865, "IRBESARTAN": 5.592911012115222, "KYMRIAH": 1.6658303454948613, "LEFLUNOMIDE": 4.150563339078497, "LUTETIUM": 19.2508836720835, "METFORMIN": 12.905443169736596, "METHOTREXATE": 7.964291621386266, "MICARDIS": 4.52435770638701, "NEXAVAR": 1.8642238195244143, "OMALIZUMAB": 31.539085377525303, "ORENCIA": 14.86984103462028, "PANTOPRAZOLE": 14.128350794261628, "PAZOPANIB": 4.562947080318598, "PRIVIGEN": 1.9617744045885397, "RASILEZ": 24.80130467433001, "RITUXIMAB": 20.00641794514234, "SILDENAFIL": 2.83232864221768, "STIVARGA": 1.5650126891894771, "SUTENT": 1.2187068830969898, "TELMISARTAN": 3.729874266038971, "VALSARTAN": 3.873286406434437, "VOTRIENT": 1.2344367386001371, "XOLAIR": 2.830253663699947, "null": 1.4332067737251444}
\ No newline at end of file
+{"null": 0.4340993310328067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11340.json
new file mode 100644
index 00000000000..28c9315c5fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11340.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11341.json
new file mode 100644
index 00000000000..b22c4ec362e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11341.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7234223214852681, "null": 0.7591107809894673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11342.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11342.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11343.json
new file mode 100644
index 00000000000..ce15cd871b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11343.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.197883913512498, "DOCETAXEL": 36.32492223547745, "ELIQUIS": 1.741804372547905, "NOVOSEVEN": 109.26752282674882, "SPIKEVAX": 0.5054586943910303, "TOZINAMERAN": 0.5330807256103234, "VAXZEVRIA": 0.6596976162906572, "null": 0.4838162787764464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11344.json
new file mode 100644
index 00000000000..d048e842f3f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11344.json
@@ -0,0 +1 @@
+{"null": 1.9979973112836964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11345.json
new file mode 100644
index 00000000000..da2782d1bf6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11345.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 1.616686431439081, "AMINOSALICYLIC": 11.514146684966835, "BENLYSTA": 5.275554677179038, "CELLCEPT": 2.3080052551448937, "CICLOSPORIN": 3.4048356684768244, "CIMZIA": 4.195368405201179, "COMIRNATY": 0.3153193607037109, "COSENTYX": 4.775363978644431, "ENTYVIO": 3.281196010387264, "HUMIRA": 5.285094406043013, "JARDIANCE": 1.3697214800541222, "KETOCONAZOLE": 74.53458561849743, "LEVOFLOXACIN": 2.3793251749323785, "PEGASYS": 2.2214322708335352, "RINVOQ": 4.1075232480520745, "ROACTEMRA": 8.388225142965503, "SIMPONI": 5.851243638801417, "SPIKEVAX": 0.2077904761484394, "STELARA": 4.258358248157225, "SUTENT": 0.8973765458426987, "VAXZEVRIA": 0.1277337798358171, "XELJANZ": 1.862586649685384, "ZOSTAVAX": 1.6314668535462922, "null": 0.7399767130194382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11346.json
new file mode 100644
index 00000000000..c1c8906f1ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11346.json
@@ -0,0 +1 @@
+{"null": 0.809811682955197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11347.json
new file mode 100644
index 00000000000..baa67d5116f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11347.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": 11.822012429685198, "null": 1.6152871511990552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11348.json
new file mode 100644
index 00000000000..a2fc8ae8b04
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11348.json
@@ -0,0 +1 @@
+{"BRILIQUE": 13.86558182104534, "BRINTELLIX": 4.774042756664849, "CLOPIDOGREL": 15.039404078432211, "COMIRNATY": 0.3486848065071375, "EFIENT": 25.52917955779758, "ELIQUIS": 7.732019078401953, "ENOXAPARIN": 15.1129362986102, "LIXIANA": 7.930173410645819, "PLAVIX": 10.83269508356056, "SPIKEVAX": 0.1227658503477695, "VAXZEVRIA": 0.1752641582240195, "XARELTO": 12.316947880461283, "null": 2.3722784155774743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11349.json
new file mode 100644
index 00000000000..fb70631b5ed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11349.json
@@ -0,0 +1 @@
+{"null": 1.31247000840049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1135.json
index 387f8293625..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1135.json
@@ -1 +1 @@
-{"ARANESP": 25.08568241506981, "SOLIRIS": 118.76351582461368}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11350.json
new file mode 100644
index 00000000000..d511bd3f0b6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11350.json
@@ -0,0 +1 @@
+{"null": 1.2888650102821348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11351.json
new file mode 100644
index 00000000000..a3e97c42e2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11351.json
@@ -0,0 +1 @@
+{"APIXABAN": 1.069770718366766, "ARIXTRA": 28.4468661081193, "ASPARAGINASE": 0.9873618033279568, "AVANDIA": 0.525692305302356, "AVASTIN": 0.7961786119448486, "BRILIQUE": 18.466324639495884, "CELLCEPT": 0.706441611469053, "CICLOSPORIN": 0.3072529457255521, "CLOPIDOGREL": 12.61196839097042, "COMIRNATY": 0.0972426394520776, "CYMBALTA": 0.3239750733718133, "CYTARABINE": 1.2971085050065732, "DEFITELIO": 11.830100610499509, "EFIENT": 25.389920420506563, "ELIQUIS": 19.3770015313182, "ENOXAPARIN": 10.964894370530423, "EPIVIR": 2.282145280074888, "ESOMEPRAZOLE": 1.6686187031390014, "EVENITY": 3.341747108730501, "EXJADE": 1.1840503732316874, "FENTANYL": 0.508617418088441, "GLIVEC": 4.243015128614345, "HEMLIBRA": 5.7370897854496885, "HUMALOG": 0.3455437762822514, "INFANRIX": 2.6638136590822263, "JAKAVI": 2.194375579029814, "JANUVIA": 0.6808612933862274, "JARDIANCE": 0.2299589013173947, "KEPPRA": 0.96937963790572, "KEYTRUDA": 0.2022386505848976, "LANTUS": 0.7587351302641273, "LEVETIRACETAM": 0.4967286272025393, "LIXIANA": 9.90758528625753, "METHOTREXATE": 0.3992792880869867, "MICARDIS": 0.9926852616817158, "NEXAVAR": 0.3242165307795076, "NPLATE": 3.1179691023027325, "OLANZAPINE": 0.3049573910568479, "OPSUMIT": 0.9705229051295706, "PEGASYS": 0.3522909435173967, "PEGINTRON": 0.8192454779588261, "PLAVIX": 30.882519613449368, "PRADAXA": 10.348954693550738, "PRASUGREL": 15.92770024575651, "SOLIRIS": 0.4457641811085059, "SOVALDI": 1.961300060398737, "SPIKEVAX": 0.0682628768564259, "SPRYCEL": 3.094663916061771, "SUTENT": 0.1639344644932049, "TASIGNA": 1.1172209849138854, "TICAGRELOR": 4.562433482018913, "TOZINAMERAN": 0.0591903838802686, "TRACLEER": 0.5037743601534241, "VAXZEVRIA": 0.09653565012688, "VIAGRA": 0.9566124481712184, "VIDAZA": 28.560072759698897, "XARELTO": 12.921724845679815, "XOFIGO": 3.643634650229967, "XTANDI": 1.6045938205475738, "ZYPREXA": 0.41930097775769, "null": 1.8451612857102464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11352.json
new file mode 100644
index 00000000000..d0163c13251
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11352.json
@@ -0,0 +1 @@
+{"null": 2.664468274757791}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11353.json
new file mode 100644
index 00000000000..7a64443ca73
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11353.json
@@ -0,0 +1 @@
+{"ARIXTRA": 37.39592895397138, "BRILIQUE": 6.935549041714955, "CLOPIDOGREL": 11.656511457745468, "COMIRNATY": 0.1066214329041501, "CYTARABINE": 2.442995380310994, "ELIQUIS": 15.207923514575429, "ENOXAPARIN": 12.60263181381288, "PLAVIX": 15.220917164294056, "VAXZEVRIA": 0.1222912611245353, "XARELTO": 8.478360325915741, "null": 2.300113573281717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11354.json
new file mode 100644
index 00000000000..1e08106e4cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11354.json
@@ -0,0 +1 @@
+{"null": 0.5291020010669022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11355.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11355.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11356.json
new file mode 100644
index 00000000000..89d602bf857
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11356.json
@@ -0,0 +1 @@
+{"null": 1.5265352755504136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11357.json
new file mode 100644
index 00000000000..a3bfc9f841c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11357.json
@@ -0,0 +1 @@
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11358.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11358.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11359.json
new file mode 100644
index 00000000000..798344088db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11359.json
@@ -0,0 +1 @@
+{"null": 1.87083069145616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1136.json
index 69d9b0077c2..101f31ecb2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1136.json
@@ -1 +1 @@
-{"ABILIFY": 1364.0484434078382, "ARIPIPRAZOLE": 57.97388693645858}
\ No newline at end of file
+{"AIMOVIG": 23.186656805414824, "BRIVIACT": 86.71754002694297, "COMIRNATY": 0.8626101708984932, "FYCOMPA": 22.55356930889413, "KEPPRA": 32.08199012750153, "LACOSAMIDE": 14.354161164108277, "LEVETIRACETAM": 16.286123382144673, "SPIKEVAX": 0.4593479448175301, "TOZINAMERAN": 1.4027015101213935, "VAXZEVRIA": 0.5296585895394621, "VIMPAT": 26.866118462741696, "null": 0.8200966445582499}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11360.json
new file mode 100644
index 00000000000..cef4462511f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11360.json
@@ -0,0 +1 @@
+{"HEMLIBRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11361.json
new file mode 100644
index 00000000000..ab419f79ec4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11361.json
@@ -0,0 +1 @@
+{"MMRVAXPRO": 33.10253415526421, "null": 2.22596685951863}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11362.json
new file mode 100644
index 00000000000..162a9669e53
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11362.json
@@ -0,0 +1 @@
+{"AVASTIN": 17.789236553268882, "COMIRNATY": 0.0830500608998901, "STELARA": 5.063806943517454, "STIVARGA": 5.516226425844927, "TOVIAZ": 13.920481368522324, "null": 1.797751336112794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11363.json
new file mode 100644
index 00000000000..25dbc3a19e3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11363.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.3733975517030044, "null": 0.6254185669913596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11364.json
new file mode 100644
index 00000000000..6be392af2a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11364.json
@@ -0,0 +1 @@
+{"AVASTIN": 13.800457352485596, "BEOVU": 388.3549573386, "BEVACIZUMAB": 16.707018535993747, "BRAFTOVI": 32.242377527463496, "BROLUCIZUMAB": 590.32492324649, "EYLEA": 264.26403479192027, "JETREA": 2367.188877863163, "null": 0.2645905527136971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11365.json
new file mode 100644
index 00000000000..0daff132cee
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11365.json
@@ -0,0 +1 @@
+{"ABILIFY": 3.5243071577217524, "ANTIBIOTICS": 8.95778877498611, "ANTIDEPRESSANTS": 90.91997633762354, "ARIPIPRAZOLE": 1.1194830736233417, "BENZODIAZEPINE": 46.285851496270766, "BENZODIAZEPINES": 86.0903870279452, "BUMETANIDE": 10.415776977316725, "BUPRENORPHINE": 49.46701388083867, "CAFFEINE": 20.207577378223093, "CANNABIDIOL": 7.623263944840117, "FENTANYL": 22.11762750065504, "IBUPROFEN": 2.404189430538381, "LYRICA": 1.9802577310538785, "MIDAZOLAM": 2.8198012826184016, "NOT": 1.9850751974287264, "OLANZAPINE": 1.748058149992871, "OPIOIDS": 107.88791336990845, "OTHER": 37.17149324059408, "PEGASYS": 0.1452438926026682, "POPPERS": 128.38687960271358, "PREGABALIN": 6.8057716548838965, "SUBOXONE": 110.84004521298532, "SUBSTANCE": 39.7798324017028, "ZYPREXA": 0.3778960762037447, "null": 2.9439026688965564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11366.json
new file mode 100644
index 00000000000..d48e7267a59
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11366.json
@@ -0,0 +1 @@
+{"null": 10.493241937853377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11367.json
new file mode 100644
index 00000000000..62b3ef76274
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11367.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 5.164012211007461, "FENTANYL": 51.43757104133166, "SUBOXONE": 9.865783295530507, "null": 6.327287536039472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11368.json
new file mode 100644
index 00000000000..8f6ce19b6be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11368.json
@@ -0,0 +1 @@
+{"ABILIFY": 287.56873454484, "APIDRA": 12.852154290783206, "ARIPIPRAZOLE": 12.07500728793456, "BUPRENORPHINE": 16.85408616980267, "GARDASIL": 3.1297115722718534, "PEGINTRON": 4.424820512520087, "null": 0.6462180419999698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11369.json
new file mode 100644
index 00000000000..68c7f8f7e38
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11369.json
@@ -0,0 +1 @@
+{"BENZODIAZEPINE": 20.759470465012463, "BUPRENORPHINE": 158.8569484602725, "CANNABIDIOL": 89.64153421599345, "CYMBALTA": 0.9245366195259204, "FENTANYL": 10.905775720800218, "LYRICA": 3.103860242551961, "OLANZAPINE": 1.071892410337454, "PREGABALIN": 7.872564141435303, "SUBOXONE": 8.270914328273994, "null": 4.332526436391872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1137.json
index d67eb5d0d6b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1137.json
@@ -1 +1 @@
-{"null": 1.5639789959179722}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11370.json
new file mode 100644
index 00000000000..d099207b7a2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11370.json
@@ -0,0 +1 @@
+{"null": 0.5703274743427723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11371.json
new file mode 100644
index 00000000000..a85aa2dadaa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11371.json
@@ -0,0 +1 @@
+{"ABILIFY": 21.302382393684244, "ANTIBIOTICS": 64.38417378455624, "BUPRENORPHINE": 14.270745130389349, "CYMBALTA": 1.8345700361354569, "DEXAMETHASONE": 5.307561504539303, "KEPPRA": 2.048469149194802, "LEVETIRACETAM": 23.825084299295536, "LEVOFLOXACIN": 6.244915249959498, "OLANZAPINE": 22.210183903627883, "PEGASYS": 1.469597760521188, "ZONISAMIDE": 120.2758147956934, "null": 1.3220850247045717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11372.json
new file mode 100644
index 00000000000..c5fd20ce8fd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11372.json
@@ -0,0 +1 @@
+{"null": 5.542014326682577}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11373.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11373.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11374.json
new file mode 100644
index 00000000000..2d9fe5bfaa1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11374.json
@@ -0,0 +1 @@
+{"ABILIFY": 6.057748536867237, "AVANDAMET": 12.478341212113836, "AVANDIA": 16.255661799610106, "COMIRNATY": 0.3433235895000814, "ENTRESTO": 9.954921975853894, "MULTAQ": 8.523491933733446, "OLANZAPINE": 14.03453845673455, "PEGASYS": 0.439282027785646, "PLAVIX": 0.9264278380232148, "SPIKEVAX": 0.2382220846884316, "TRACLEER": 5.055599712276701, "VAXZEVRIA": 1.0619614603904834, "VIAGRA": 2.0580218466295013, "ZYPREXA": 2.0408116117964887, "null": 2.2939559206035742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11375.json
new file mode 100644
index 00000000000..c2fb4434192
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11375.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.9434354733067996, "ADENURIC": 4.7770095456983945, "AMINOSALICYLIC": 1.8456575669306672, "ARIPIPRAZOLE": 0.8764018346651167, "AVANDIA": 1.4876807925297308, "BEDAQUILINE": 3.55551732828071, "BRINTELLIX": 0.7458879457326261, "CHAMPIX": 1.6390788805226872, "COMIRNATY": 0.968264232887308, "CYMBALTA": 0.329750988502825, "DEXAMETHASONE": 0.6851420194966806, "DOCETAXEL": 0.8500822565171585, "EFIENT": 11.684375460323032, "ELIQUIS": 1.3750167343213195, "ENTRESTO": 5.656351127387332, "EPIVIR": 3.73143393117829, "ESOMEPRAZOLE": 2.200998294560316, "EVENITY": 4.108090162567711, "FENTANYL": 0.7274481618508665, "GARDASIL": 0.467726194039979, "HARVONI": 4.510365483104159, "HUMALOG": 0.2937435781981806, "ICLUSIG": 3.120851558584854, "INCIVO": 1.3013280456293497, "JAKAVI": 2.0795804202266748, "JANUVIA": 0.6765842616807275, "JARDIANCE": 0.4677222987854583, "KALETRA": 2.1657726711618808, "KEPPRA": 2.7888213139369227, "KEYTRUDA": 1.2888080538806073, "KYPROLIS": 2.90004545709605, "LANTUS": 0.3397331607658024, "LATUDA": 1.956675788197104, "LEVETIRACETAM": 0.5786175198193237, "MIDAZOLAM": 2.672184478225242, "MULTAQ": 3.38538492458209, "NEORECORMON": 33.9341003316681, "NEXAVAR": 1.4249631682145891, "OLANZAPINE": 3.575593560797938, "OLYSIO": 5.140131934387264, "OPDIVO": 1.1023838048800725, "OPSUMIT": 3.0444604922469, "PEGASYS": 0.532386837405623, "PEGINTRON": 0.5270314983118394, "PLAVIX": 1.1183656851382102, "PRADAXA": 7.912163178128317, "PREVENAR": 4.542776908942881, "REVATIO": 2.141028952056084, "SILDENAFIL": 3.612248808174224, "SIMPONI": 0.3557340895635285, "SOLIRIS": 0.8252798682989069, "SOMATROPIN": 18.379653723577015, "SPIKEVAX": 0.427807545785588, "SPINRAZA": 4.056151798283298, "STELARA": 0.2831758302999015, "SUTENT": 0.6638845526285316, "SYNAGIS": 4.802617068440646, "TAMIFLU": 6.505371193564982, "TASIGNA": 1.2608624783179698, "TOZINAMERAN": 0.2618456092922121, "TRACLEER": 6.911537933427729, "VAXZEVRIA": 0.4160113106875154, "VIAGRA": 5.247155493449808, "VICTOZA": 1.610339363928356, "VIMPAT": 1.6772975374459314, "VOTRIENT": 0.7025049136163819, "ZYPREXA": 7.7719381651965245, "null": 1.0464475179942716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11376.json
new file mode 100644
index 00000000000..dcdaec5b51b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11376.json
@@ -0,0 +1 @@
+{"CHAMPIX": 1.3570958535094015, "COMIRNATY": 3.444146254195419, "GARDASIL": 0.4758161380263515, "JARDIANCE": 0.6512248171353285, "PEGASYS": 2.162228198410713, "PEGINTERFERON": 2.9991412085072646, "PEGINTRON": 5.70686964067958, "ROACTEMRA": 2.092164880108192, "SHINGRIX": 1.9648940469046643, "SILDENAFIL": 7.160311971399755, "SPIKEVAX": 1.909690747817994, "STELARA": 0.938218739510386, "TOZINAMERAN": 1.2220746291377678, "TRUVADA": 0.2659977213886332, "VAXZEVRIA": 1.1734887710304904, "VIAGRA": 10.130752094237904, "ZOSTAVAX": 1.2498272736203686, "null": 0.3813736969503564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11377.json
new file mode 100644
index 00000000000..7ab67a24c19
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11377.json
@@ -0,0 +1 @@
+{"HEXYON": 234.6567004896544, "INFANRIX": 73.72642031541899, "PREVENAR": 93.14758178177584, "ROTATEQ": 45.34884902881807, "SUBOXONE": 15.34483005700388, "SYNAGIS": 133.33402067364332, "null": 1.496613073233574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11378.json
new file mode 100644
index 00000000000..ff84165f5c8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11378.json
@@ -0,0 +1 @@
+{"AZILECT": 61.26216181591614, "CARBIDOPA": 110.165108922598, "COMIRNATY": 0.529147329846708, "COMTAN": 117.08395008402184, "LYRICA": 5.415252313638984, "SIFROL": 105.48880376705112, "SPIKEVAX": 0.2822286195948897, "STALEVO": 37.57989661377093, "VAXZEVRIA": 0.2364557362434197, "null": 2.1375182752926043}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11379.json
new file mode 100644
index 00000000000..bf2870a9507
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11379.json
@@ -0,0 +1 @@
+{"BRIVIACT": 107.99430888683808, "FYCOMPA": 107.67430235135168, "KEPPRA": 42.72779674777096, "LACOSAMIDE": 60.46357006754184, "LEVETIRACETAM": 94.57816240155756, "VIMPAT": 95.01405375128653, "null": 1.0080375473782248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1138.json
index 6e0e390601f..17d7f8a669e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1138.json
@@ -1 +1 @@
-{"ABILIFY": 11.718153295184276, "ARIPIPRAZOLE": 15.305654980635182, "BRINTELLIX": 13.212266944216598, "CARIPRAZINE": 136.79080639331687, "CYMBALTA": 1.891240326020683, "INVEGA": 141.64254342732255, "LATUDA": 26.334610390357557, "MELATONIN": 16.034255045091797, "OLANZAPINE": 29.073941991485032, "RISPERIDONE": 22.948509763138265, "ZYPREXA": 21.685241915982584, "null": 2.560482093641748}
\ No newline at end of file
+{"COMIRNATY": 0.7293642622692218, "SPIKEVAX": 0.6894932121257679, "VAXZEVRIA": 0.5362511199050228, "null": 1.1394315614549522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11380.json
new file mode 100644
index 00000000000..05a8a1e09f5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11380.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6571879672886379, "EYLEA": 60.43747962727947, "PEGASYS": 6.140997253798575, "TOZINAMERAN": 1.50778066372557, "VAXZEVRIA": 0.7154490942058278, "null": 0.8902796140333764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11381.json
new file mode 100644
index 00000000000..cdf3495909c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11381.json
@@ -0,0 +1 @@
+{"BRILIQUE": 7.007232212910333, "BUDESONIDE": 1.2479860591700085, "CHAMPIX": 1.8180534851463048, "COMIRNATY": 0.804648863356843, "FORSTEO": 1.7389275654554273, "SPIKEVAX": 0.4730426869472482, "SUTENT": 0.5422813623324467, "TOZINAMERAN": 0.488855976268142, "VAXZEVRIA": 0.3605463317347245, "XOLAIR": 2.384472788429843, "null": 2.740370780808252}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11382.json
new file mode 100644
index 00000000000..a6e35cb7b8c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11382.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11383.json
new file mode 100644
index 00000000000..43c331b5b69
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11383.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11384.json
new file mode 100644
index 00000000000..4e4c8a5ffb8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11384.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11385.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11385.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11386.json
new file mode 100644
index 00000000000..0f77a345478
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11386.json
@@ -0,0 +1 @@
+{"null": 1.813720501064644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11387.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11387.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11388.json
new file mode 100644
index 00000000000..abbe2d6fecc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11388.json
@@ -0,0 +1 @@
+{"SOMATROPIN": 1290.8221809123604, "null": 1.574165341041632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11389.json
new file mode 100644
index 00000000000..5ec438a3211
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11389.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.107636116309701, "COSENTYX": 3.0919574755562618, "COTELLIC": 17.956077288190652, "ESBRIET": 48.74991258560205, "OLYSIO": 74.22520496059998, "PEGASYS": 1.0240263725001977, "RUBRACA": 13.300510090289832, "SPIKEVAX": 0.2270057035957591, "SUTENT": 1.251910727625403, "TOZINAMERAN": 0.6221566129780539, "VAXZEVRIA": 0.2565032580634696, "VFEND": 15.33528110313298, "XOLAIR": 1.7922048853321555, "ZELBORAF": 163.6866523612104, "null": 1.5704999008906846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1139.json
index 532a384dfb3..e037dacc0a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1139.json
@@ -1 +1 @@
-{"null": 1.8216899779654017}
\ No newline at end of file
+{"ABILIFY": 1.5708804956211797, "AVAMYS": 3.58904724079506, "COMIRNATY": 0.0112874036974249, "GARDASIL": 0.902900195530415, "HUMALOG": 0.4736609449772243, "INFANRIX": 28.12897226244677, "KEPPRA": 2.687610712276309, "LATUDA": 4.739382727609009, "LEVETIRACETAM": 2.510656572976363, "MMRVAXPRO": 7.920540263553834, "NOT": 14.287018105182112, "OLANZAPINE": 0.8998243174974807, "PREVENAR": 28.40843170151181, "PROQUAD": 110.57317315744714, "ROTASHIELD": 218.0674426706356, "SPINRAZA": 5.348817702298185, "SUBOXONE": 1.6595041970839266, "TOZINAMERAN": 0.1409591316335325, "XELJANZ": 0.4066306297686974, "ZYPREXA": 0.8443045774098253, "null": 8.837315413870092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11390.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11390.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11391.json
new file mode 100644
index 00000000000..4083024ece8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11391.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2218453107933301, "null": 0.6291563255451236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11392.json
new file mode 100644
index 00000000000..dc5b7154d7d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11392.json
@@ -0,0 +1 @@
+{"null": 2.5145325662297564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11393.json
new file mode 100644
index 00000000000..9df3bb1c25e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11393.json
@@ -0,0 +1 @@
+{"NILOTINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11394.json
new file mode 100644
index 00000000000..2bcc0d03a36
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11394.json
@@ -0,0 +1 @@
+{"CIALIS": 572.684034684605, "VIAGRA": 136.80159954403308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11395.json
new file mode 100644
index 00000000000..269ffbb3d16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11395.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.8386565852706105, "VAXZEVRIA": 2.2391753870412474, "null": 0.2841515100470868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11396.json
new file mode 100644
index 00000000000..f0c3cf4fd47
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11396.json
@@ -0,0 +1 @@
+{"ACTRAPID": 9.912164278037086, "APIXABAN": 2.296454018113001, "ATOSIBAN": 41.86480049884824, "CELECOXIB": 11.24812065123724, "CLOPIDOGREL": 0.8119731515309511, "COMIRNATY": 2.6616735620181995, "ELIQUIS": 1.217053847035902, "EVISTA": 12.322713388550582, "MODERNA": 2.3429111653225085, "PEGASYS": 0.3169357425580792, "PROTELOS": 19.09748379497525, "RINVOQ": 2.419650249940031, "SPIKEVAX": 0.9835863509122028, "TOZINAMERAN": 0.4279844292806701, "VAXZEVRIA": 3.454196932347737, "XELJANZ": 0.5996183046632855, "null": 0.4452341032493326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11397.json
new file mode 100644
index 00000000000..6929fe70a67
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11397.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1280117760404283, "IBUPROFEN": 9.5817257377611, "RINVOQ": 10.964382100420629, "null": 1.237267520233427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11398.json
new file mode 100644
index 00000000000..06e8493ddbe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11398.json
@@ -0,0 +1 @@
+{"ABACAVIR": 23.86035221745633, "COMIRNATY": 0.4229020473636268, "null": 0.5190976927156924}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11399.json
new file mode 100644
index 00000000000..d379008a45f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11399.json
@@ -0,0 +1 @@
+{"null": 1.920349924069633}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/114.json
index 97820128158..fe6ea90afed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/114.json
@@ -1 +1 @@
-{"METHOTREXATE": 27.84286958552345, "null": 1.5994533208886923}
\ No newline at end of file
+{"ABILIFY": 0.292022191906418, "ACTRAPID": 4.187485096400902, "ADALIMUMAB": 0.6781727312464766, "AERIUS": 3.0090732507387963, "APIDRA": 2.167505600030016, "ARANESP": 0.2734523101941043, "ARIPIPRAZOLE": 0.4798213190076818, "AVANDIA": 0.3726139789663926, "BENZODIAZEPINE": 5.519445121223284, "BENZODIAZEPINES": 14.4873249797832, "BRINTELLIX": 0.884952530912994, "BUDESONIDE": 0.2316912649183961, "BUPIVACAINE": 1.1540377929243943, "BUPRENORPHINE": 6.532707696951065, "BYETTA": 0.3180003311266227, "CICLOSPORIN": 0.2953677040713909, "CLOPIDOGREL": 0.4983462022082476, "COAPROVEL": 2.5127974567089577, "COMIRNATY": 0.0190365458479669, "CYMBALTA": 0.7132198735337358, "DULOXETINE": 3.0724106177619634, "EBIXA": 8.563238953198683, "ELIQUIS": 0.632771231095957, "EPCLUSA": 1.567735324059847, "ESOMEPRAZOLE": 1.7661590966882872, "EVISTA": 0.8972425881869398, "FAMPYRA": 0.6981744116137145, "FENTANYL": 7.296696509051243, "FIASP": 2.3073072133805352, "FORSTEO": 2.263475022174904, "FYCOMPA": 3.253932905014447, "GLIBENCLAMIDE": 6.221685489167692, "GLUCAGON": 5.725508664208805, "HUMALOG": 1.215002364647387, "IBRANCE": 0.153251043290734, "IBUPROFEN": 3.6926340494637753, "INSULIN": 2.101248798852428, "JEVTANA": 2.726638118135794, "KALETRA": 2.0168152467758995, "KEPPRA": 2.665715939114686, "LANTUS": 2.804037901729704, "LATUDA": 1.223094653374395, "LEVEMIR": 2.731172718201436, "LEVETIRACETAM": 1.9455989874015305, "LEVODOPA": 2.822563514884808, "LYRICA": 0.598155870914633, "MELATONIN": 2.917986137475613, "METHOTREXATE": 0.4556717676625406, "MICARDIS": 0.7302374647179868, "MIDAZOLAM": 3.276919895094155, "MOVYMIA": 10.739194637913451, "NOT": 1.5515672150577402, "NOVORAPID": 2.493627884325964, "NOXAFIL": 1.608354093609624, "OLANZAPINE": 3.2736371967975995, "OLYSIO": 1.30296757733378, "OPIOIDS": 16.81550769169097, "OPSUMIT": 0.4407796778148179, "OXYBUTYNIN": 7.830287933504132, "PEGASYS": 0.3217190724423976, "PEGINTRON": 0.2846928723412357, "PLAVIX": 0.6417261809376948, "PREGABALIN": 11.207150682832106, "PROPRANOLOL": 2.425937193683861, "RELVAR": 1.8111181865255257, "SPIKEVAX": 0.0475019496942561, "SUBOXONE": 3.906658058374752, "TAMIFLU": 1.2714277274332255, "TEMODAL": 2.021944068519444, "TOVIAZ": 1.073572798633467, "TOZINAMERAN": 0.0589460543152397, "TRESIBA": 2.629133026650079, "TRULICITY": 2.658208553952218, "TRUVADA": 0.1302616813390074, "TWINRIX": 1.356402867380287, "VFEND": 1.013658156478193, "VIAGRA": 1.1366848369636366, "VICTOZA": 1.2495049892604349, "VIMPAT": 1.6645113739010615, "VORICONAZOLE": 0.9276427356012364, "XELJANZ": 0.1732184442416667, "XTANDI": 0.3846252717305469, "XYREM": 1.3005724455223069, "ZYPREXA": 2.174367119340546, "null": 4.623765951121345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1140.json
index d55649bb866..8222511c65f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1140.json
@@ -1 +1 @@
-{"AFINITOR": 1.841890879447576, "AMINOSALICYLIC": 8.781584017184526, "BEDAQUILINE": 23.183203866524103, "BUMETANIDE": 4.240698395150697, "CABOMETYX": 1.746723271318583, "CELECOXIB": 5.9992140814998285, "CELLCEPT": 1.3286915481082575, "CYMBALTA": 2.3625331151888376, "CYTARABINE": 1.199929229882496, "DELAMANID": 11.16753490058625, "EMEND": 4.766771884988119, "ENTRESTO": 4.038709982335565, "ESBRIET": 4.045479122789641, "EXFORGE": 4.7885294592827, "EXJADE": 3.4005929509187056, "FIRDAPSE": 4.26185594098968, "HIZENTRA": 1.528665807536341, "HYCAMTIN": 8.21096265461587, "IBRANCE": 1.7309890329101203, "INLYTA": 2.060608542929566, "IRBESARTAN": 3.6257053742040894, "JARDIANCE": 1.006793478272368, "KARVEZIDE": 37.23097521524178, "KEPPRA": 1.7039723948238827, "KEYTRUDA": 2.344088799512093, "LEVEMIR": 1.003860993585754, "LEVETIRACETAM": 1.418613124359818, "LYRICA": 2.1162756922365715, "MEKINIST": 2.3583757126130926, "MICARDIS": 5.391005174904916, "NEXAVAR": 1.2196635768839243, "OFEV": 1.0341660975708704, "OLANZAPINE": 1.548733931947412, "OPDIVO": 1.253733176138875, "OPSUMIT": 1.9616116165651316, "PEGASYS": 1.4294229711685342, "REVATIO": 1.8742438953437237, "RUBRACA": 2.591703245579112, "SPRYCEL": 1.0984736251984693, "STIVARGA": 1.2327839631632698, "SUTENT": 3.658669198138153, "TAGRISSO": 2.0135075514031517, "TRELEGY": 1.4747180934025974, "VFEND": 1.220514612461744, "VIMPAT": 1.6131150404427594, "VOTRIENT": 2.5845965020242723, "XTANDI": 1.2199056272948685, "XYREM": 2.5091136657630977, "YERVOY": 2.480488946750292, "ZYPREXA": 2.450780305457465, "null": 2.038708358154325}
\ No newline at end of file
+{"COMIRNATY": 4.524641230985584, "SPIKEVAX": 0.8852857309737729, "VAXZEVRIA": 0.3841393995746127, "null": 0.3829274302029516}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11400.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11400.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11401.json
new file mode 100644
index 00000000000..320d47a1ec9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11401.json
@@ -0,0 +1 @@
+{"IBUPROFEN": 72.34785944470897, "OMALIZUMAB": 76.9554836299629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11402.json
new file mode 100644
index 00000000000..157af300689
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11402.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 110.17746461657556, "COMIRNATY": 0.3447987808767446, "ONCASPAR": 175.0772413754705, "SPIKEVAX": 0.40480814430935, "TOZINAMERAN": 0.8303284165070584, "VAXZEVRIA": 3.275025816556229, "null": 0.5866210387580184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11403.json
new file mode 100644
index 00000000000..21a8b709818
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11403.json
@@ -0,0 +1 @@
+{"null": 0.7673534021882098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11404.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11404.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11405.json
new file mode 100644
index 00000000000..512b414d3a4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11405.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 5.811338842542092, "null": 0.7432728858619766}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11406.json
new file mode 100644
index 00000000000..446c817514a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11406.json
@@ -0,0 +1 @@
+{"null": 0.9536240008229327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11407.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11407.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11408.json
new file mode 100644
index 00000000000..adea616a844
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11408.json
@@ -0,0 +1 @@
+{"null": 1.6086976435080844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11409.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11409.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1141.json
index 47283c263c2..bd0cab8f239 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1141.json
@@ -1 +1 @@
-{"ESOMEPRAZOLE": 19.54787531681773, "EXJADE": 6.069592874776522, "JARDIANCE": 3.662972413178385, "MICARDIS": 13.96356574100327, "MIDAZOLAM": 12.322947252034432, "OLANZAPINE": 6.541851133824914, "SUTENT": 2.228579761191265, "null": 2.1254556562260185}
\ No newline at end of file
+{"COMIRNATY": 4.192998844844487}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11410.json
new file mode 100644
index 00000000000..a731f5789bc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11410.json
@@ -0,0 +1 @@
+{"COMIRNATY": 7.379908051572757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11411.json
new file mode 100644
index 00000000000..385fd47ca57
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11411.json
@@ -0,0 +1 @@
+{"null": 1.4703514992816136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11412.json
new file mode 100644
index 00000000000..717f1bc4855
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11412.json
@@ -0,0 +1 @@
+{"AVANDIA": 1.3512351343749358, "BRILIQUE": 4.248667303108736, "COMIRNATY": 1.0184637974121735, "CYMBALTA": 1.7449774158108642, "EVEROLIMUS": 21.498535698713088, "FENTANYL": 1.5863095818146928, "FORSTEO": 1.9968472246084568, "GARDASIL": 0.8812750594340371, "IRBESARTAN": 20.880086495906045, "SPIKEVAX": 0.6309777545010754, "TASIGNA": 5.320197491737713, "TOZINAMERAN": 0.5965319295686179, "VAXZEVRIA": 0.0885151320807335, "ZOSTAVAX": 1.2679924570331749, "ZYPREXA": 2.0136786817885395, "null": 1.5517492972354676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11413.json
new file mode 100644
index 00000000000..06fb866fd67
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11413.json
@@ -0,0 +1 @@
+{"null": 0.8249481424895455}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11414.json
new file mode 100644
index 00000000000..faf761e3b52
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11414.json
@@ -0,0 +1 @@
+{"ACTRAPID": 11.643428819285306, "AIMOVIG": 0.6900395305495757, "ARANESP": 3.6875901370568687, "ARIPIPRAZOLE": 0.919240864559897, "AVANDAMET": 9.139617413033282, "AVANDIA": 7.62513411611777, "AVASTIN": 1.2203640727030534, "BRIDION": 12.379022920905095, "CHAMPIX": 1.1074776883028483, "CLOPIDOGREL": 0.5069985061210945, "COMIRNATY": 0.5141928282759148, "CYMBALTA": 0.7530126615608235, "DASATINIB": 31.228357974255932, "ELIQUIS": 0.197204076042596, "ENTRESTO": 0.8305108466997522, "ENTYVIO": 1.1969618118160334, "FENTANYL": 2.354020718875351, "FIRDAPSE": 3.159163250369585, "FORSTEO": 0.6792040010145294, "GARDASIL": 0.4044641566778661, "HUMALOG": 0.3819227185638794, "HUMIRA": 1.739202322052016, "IBUPROFEN": 0.9203683569532244, "ICLUSIG": 2.224836690995568, "KEPPRA": 0.4667324935276022, "KEYTRUDA": 0.4993222105254294, "LEVETIRACETAM": 2.713556338607779, "LEVOFLOXACIN": 0.9085859959493032, "LOPINAVIR": 7.424767570175218, "METHOTREXATE": 1.1029726367759525, "OLANZAPINE": 0.8424145876612803, "OPSUMIT": 1.066925787688059, "PEGASYS": 0.350317783598955, "PEGINTRON": 0.9789556405185056, "SPIKEVAX": 0.3977192276483651, "SYNAGIS": 1.983556143974398, "TAMIFLU": 2.7166109327417987, "TOZINAMERAN": 0.9306718548148224, "TRACLEER": 2.076142069136613, "VAXZEVRIA": 0.1846783615134356, "XOLAIR": 0.5989364705234232, "ZOSTAVAX": 0.7561749649716013, "ZYPREXA": 1.852111410440624, "null": 1.9645867968603437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11415.json
new file mode 100644
index 00000000000..977ca89d62a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11415.json
@@ -0,0 +1 @@
+{"null": 1.2685970754618725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11416.json
new file mode 100644
index 00000000000..2958545b434
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11416.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.3933215598978244, "ADALIMUMAB": 0.1349302618739184, "ALBIGLUTIDE": 51.45540116473992, "ANORO": 1.104668062678901, "APIDRA": 1.1791191837506396, "ARANESP": 1.382460818114665, "ARAVA": 0.3997443147714301, "ATRIPLA": 0.0741332552396324, "AUBAGIO": 3.3688705273841983, "AVAMYS": 0.749298636221212, "AVANDIA": 1.0766889902833874, "BARACLUDE": 4.843632526410175, "BENLYSTA": 6.626053796938585, "BRIDION": 1.989399371420688, "BYETTA": 1.1546754681066116, "CELLCEPT": 0.8238565968960637, "CHAMPIX": 0.3095482249410176, "CICLOSPORIN": 1.7705406780995394, "CIMZIA": 10.576046923724103, "COMIRNATY": 0.0216574620149954, "CYMBALTA": 0.7058982264201041, "DAKLINZA": 4.2862405217937285, "ELIQUIS": 6.007175193348304, "ENBREL": 1.7281836783014215, "ENTYVIO": 4.8135869760500976, "ERLEADA": 2.164993423318131, "EVENITY": 3.5739627670567877, "EVISTA": 3.438097913876999, "EXJADE": 1.841889218250608, "FENTANYL": 0.7619427448830319, "FORSTEO": 0.8706031112100933, "GALAFOLD": 4.916651430912984, "GARDASIL": 0.4904450391269482, "HIZENTRA": 4.641144851334939, "HUMALOG": 0.75349570083902, "HUMIRA": 2.3044968072563727, "IBRANCE": 0.7123035021695107, "INCRUSE": 4.124536575893146, "INSULIN": 0.4988543300942351, "JANUMET": 4.001559116299395, "JANUVIA": 3.776308005941461, "JARDIANCE": 4.060716903982898, "KAFTRIO": 8.295577242872083, "KALYDECO": 10.038641397065984, "KEPPRA": 1.7511459102121687, "KEYTRUDA": 1.465315615974358, "LANTUS": 4.0725744943936775, "LEVEMIR": 3.093006892682557, "LONSURF": 2.298846964427156, "LYRICA": 1.4134144292671065, "MEKINIST": 0.6957599161088612, "METHOTREXATE": 0.6138432670202306, "MIMPARA": 2.374930569350868, "MISOPROSTOL": 40.02432412518667, "NAGLAZYME": 1.730646741791828, "NEULASTA": 3.72286271617434, "NEXAVAR": 0.4781176556379853, "NOXAFIL": 2.16621510444783, "NPLATE": 3.460631573381158, "NUCALA": 2.310103549922403, "OCALIVA": 3.3667616356496044, "OFEV": 1.5231439622246212, "OPSUMIT": 3.2319451421147005, "ORKAMBI": 4.970935843249374, "PEGASYS": 0.3419761484609568, "PEGINTRON": 0.5671418172511551, "PEMBROLIZUMAB": 0.7634776213705091, "PLAVIX": 0.7786126709224234, "RASILEZ": 1.673734728579796, "RINVOQ": 3.245233338287654, "ROTATEQ": 9.262282280071972, "RUBRACA": 4.27672475825635, "RUCONEST": 4.581646733683935, "RYBELSUS": 2.507527795442816, "SAXENDA": 4.884745912418875, "SIMPONI": 16.480223027735956, "SKYRIZI": 3.848365977664933, "SOLIRIS": 0.5001194856164302, "SPIKEVAX": 0.0514898212169269, "SPRYCEL": 1.452715040817407, "STELARA": 6.675467132002495, "SUTENT": 0.1573742442735869, "SYNAGIS": 3.8455500331883306, "TEMODAL": 2.4341280729344525, "TOUJEO": 3.3646165505663075, "TRACLEER": 2.725809193865039, "TRELEGY": 5.102265560077497, "TREMFYA": 3.432402771362688, "TRUVADA": 0.0831830891481612, "VAXZEVRIA": 0.0177233735159888, "VELTASSA": 15.56228087811788, "VIAGRA": 1.2527479387852958, "VICTOZA": 2.311164174720255, "VIMPAT": 1.2599252729844057, "VOTRIENT": 3.3649221351965504, "XOLAIR": 1.569723565734621, "XTANDI": 1.6456173207893383, "ZOSTAVAX": 1.205502854719504, "null": 1.3934014893967142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11417.json
new file mode 100644
index 00000000000..c57c921ac36
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11417.json
@@ -0,0 +1 @@
+{"ARAVA": 4.603235090898995, "ENBREL": 31.26452681252403, "null": 0.5853902034906697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11418.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11418.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11419.json
new file mode 100644
index 00000000000..27a11f6c365
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11419.json
@@ -0,0 +1 @@
+{"ABACAVIR": 65.91390191458981}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1142.json
index ff3a6ab61b3..003e011ba07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1142.json
@@ -1 +1 @@
-{"SPIKEVAX": 37.80485096167001}
\ No newline at end of file
+{"COMIRNATY": 0.9712182053138262, "IPILIMUMAB": 63.58495963716963, "KEYTRUDA": 32.68322652261469, "TOZINAMERAN": 3.0855043022153428, "VAXZEVRIA": 0.8614287031536376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11420.json
new file mode 100644
index 00000000000..1410937614c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11420.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.11833589302974, "FASENRA": 0.989949054957572, "HUMIRA": 0.6745708819983134, "IBRANCE": 0.336094556090771, "JANSSEN": 56.97341002569951, "JCOVDEN": 10.343684200705374, "LEVETIRACETAM": 0.5197132235781093, "NUCALA": 0.9216419325157644, "RINVOQ": 2.4478201425573203, "RITUXIMAB": 0.8815834386981751, "SIMPONI": 0.7673873020433543, "SOLIRIS": 8.458414630457044, "SPIKEVAX": 0.5161038943165297, "STELARA": 0.3222471606299112, "TOZINAMERAN": 23.59762558146328, "VAXZEVRIA": 0.1793507206173204, "XELJANZ": 0.5160595091835474, "null": 0.0530704364999007}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11421.json
new file mode 100644
index 00000000000..86e9dcb8f4d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11421.json
@@ -0,0 +1 @@
+{"BARACLUDE": 89.52784781182268, "BIKTARVY": 5.342464289449949, "COMPLEMENT": 408.5722481012281, "HUMAN": 7.071822114470009, "JANUMET": 5.341711307521712, "KEPPRA": 1.2292399514036998, "KEYTRUDA": 1.132988211027527, "LANTUS": 2.5530011373603725, "NEXAVAR": 1.4320893574683116, "NOVORAPID": 3.3881385451670125, "PEGASYS": 1.420533321871163, "PLAVIX": 5.928089952371267, "SAXENDA": 10.071801270447484, "SUTENT": 0.6918596844850533, "VEMLIDY": 111.26280859592256, "VIAGRA": 39.69444840473262, "null": 2.1940254447847907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11422.json
new file mode 100644
index 00000000000..ad769c92d4c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11422.json
@@ -0,0 +1 @@
+{"null": 0.4279957170365024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11423.json
new file mode 100644
index 00000000000..7ffec12ec3f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11423.json
@@ -0,0 +1 @@
+{"null": 5.289645454580061}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11424.json
new file mode 100644
index 00000000000..30f14fe9bb8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11424.json
@@ -0,0 +1 @@
+{"EYLEA": 19.89031333954573, "LANTUS": 3.027255000312526, "NOVORAPID": 4.9815969261720605, "null": 9.30531452386752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11425.json
new file mode 100644
index 00000000000..b3bdc0e5b85
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11425.json
@@ -0,0 +1 @@
+{"null": 1.4957414790592432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11426.json
new file mode 100644
index 00000000000..5d5d973d605
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11426.json
@@ -0,0 +1 @@
+{"APIXABAN": 8.227768495691603, "ARIPIPRAZOLE": 10.0974205906934, "BENZODIAZEPINE": 29.675945719772667, "BUDESONIDE": 2.9233628309967323, "BUPRENORPHINE": 3.898612564274484, "CARIPRAZINE": 147.71755676053294, "CELECOXIB": 5.70348602968559, "CLOPIDOGREL": 1.8956861160145897, "DULOXETINE": 66.9011156476248, "FENTANYL": 3.9280592425224503, "IBUPROFEN": 46.90857714426173, "INSULIN": 4.04837287146744, "LEFLUNOMIDE": 5.301131889670181, "LEVETIRACETAM": 8.528941382301895, "LINACLOTIDE": 135.8599384455892, "MELATONIN": 13.557122236386848, "OLANZAPINE": 9.9570196718407, "OXYBUTYNIN": 15.88358502910902, "PANTOPRAZOLE": 13.098449687053394, "PIOGLITAZONE": 32.93100537419011, "PREGABALIN": 9.27590936644401, "RIVAROXABAN": 74.6747860796015, "SUBOXONE": 1.1443613113331608, "null": 3.305012128867989}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11427.json
new file mode 100644
index 00000000000..d5037036b85
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11427.json
@@ -0,0 +1 @@
+{"null": 3.3954208354233804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11428.json
new file mode 100644
index 00000000000..4f97a0d25c5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11428.json
@@ -0,0 +1 @@
+{"BLOOD": 2056.207203755685, "HIZENTRA": 90.43640307250324, "HUMALOG": 8.472204952114653, "PRIVIGEN": 114.04077315802948, "null": 2.718907445916165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11429.json
new file mode 100644
index 00000000000..894b43fb6a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11429.json
@@ -0,0 +1 @@
+{"CHAMPIX": 10.175205060162927, "OLANZAPINE": 25.298885349404028, "null": 1.7856354390856322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1143.json
index 57dfc49b079..8ccd3cd1e8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1143.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 186.24789616974712, "CICLOSPORIN": 186.82590107433472}
\ No newline at end of file
+{"INFLIXIMAB": 43.81774354727842, "INLYTA": 14.635524403602489, "IPILIMUMAB": 325.5770944991305, "KEYTRUDA": 37.19449774509005, "NIVOLUMAB": 276.2340299667652, "OPDIVO": 95.6025489184596, "PEMBROLIZUMAB": 49.979273710275706, "YERVOY": 250.55159493718256, "null": 0.0417024308341717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11430.json
new file mode 100644
index 00000000000..b8ccfa001c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11430.json
@@ -0,0 +1 @@
+{"null": 2.1905834985690325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11431.json
new file mode 100644
index 00000000000..2398573eef5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11431.json
@@ -0,0 +1 @@
+{"null": 1.489675645859152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11432.json
new file mode 100644
index 00000000000..f3621f48274
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11432.json
@@ -0,0 +1 @@
+{"null": 0.9274912096037992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11433.json
new file mode 100644
index 00000000000..74e2d37fe29
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11433.json
@@ -0,0 +1 @@
+{"SUTENT": 8.89144158847802, "null": 1.306346535786408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11434.json
new file mode 100644
index 00000000000..10dee1e9970
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11434.json
@@ -0,0 +1 @@
+{"null": 0.9225583663233016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11435.json
new file mode 100644
index 00000000000..2c3bcbcf82b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11435.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 32.91719261971659, "METHOTREXATE": 58.24431663935158, "null": 0.3096098963220699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11436.json
new file mode 100644
index 00000000000..0268672e3c7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11436.json
@@ -0,0 +1 @@
+{"KAFTRIO": 755.7543833475393}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11437.json
new file mode 100644
index 00000000000..a4360830003
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11437.json
@@ -0,0 +1 @@
+{"BYDUREON": 6.092929325817991, "COMIRNATY": 0.7860014434447264, "OCRELIZUMAB": 20.01630453276819, "SPIKEVAX": 0.9946158445356746, "STELARA": 4.5164585556697645, "TOZINAMERAN": 4.352045209238904, "VAXZEVRIA": 14.75842994188447, "null": 0.0189073886316131}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11438.json
new file mode 100644
index 00000000000..beb27af16a7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11438.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.0456879596924482, "ABATACEPT": 4.962751571871745, "ABILIFY": 0.4026054943538997, "ADALIMUMAB": 3.687417745070084, "ADCIRCA": 1.1469518708740665, "ADEMPAS": 1.0337686799327337, "ADENURIC": 0.9287908899285008, "ADVATE": 1.139761199358461, "AERIUS": 0.7883495364636558, "AFINITOR": 0.5179201326522819, "AIMOVIG": 0.5553320988469471, "ALDARA": 1.1955011066373464, "ALEMTUZUMAB": 0.1684565746888345, "ALIMTA": 0.162620435665779, "ALL": 0.9710190065219344, "AMBRISENTAN": 0.8923280173252356, "AMINOSALICYLIC": 0.4400618079699014, "ANAKINRA": 0.7765849803182373, "APIDRA": 0.6920590565013617, "APIXABAN": 0.0727903194541511, "APREMILAST": 2.01257633174931, "ARANESP": 0.1521781658106043, "ARAVA": 10.424559399904975, "ARIPIPRAZOLE": 0.1112957181984085, "ASPARAGINASE": 0.1506107077250911, "ATRIPLA": 0.0402405623708007, "AUBAGIO": 0.3891944986412476, "AVANDAMET": 0.736502519172391, "AVANDIA": 0.7104103667818744, "AVASTIN": 0.0958717071297086, "AZATHIOPRINE": 0.3174351689278181, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11439.json
new file mode 100644
index 00000000000..b0bc2c6339a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11439.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.1196010707096873, "AERIUS": 2.217308601403408, "AFINITOR": 0.6689451292933586, "AIMOVIG": 0.7838210611828043, "ALEMTUZUMAB": 0.2626580060134429, "APIDRA": 0.272147398487555, "APIXABAN": 0.2197194048206472, "APROVEL": 0.7611818655957565, "ARANESP": 0.3687126714189833, "ARAVA": 0.1189588393653824, "ASPARAGINASE": 0.2974592938205861, "ATAZANAVIR": 0.320387411954208, "AUBAGIO": 0.3361657505069653, "AVAMYS": 0.9535850657897418, "AVANDIA": 0.1637227537167258, "BEDAQUILINE": 0.4826059842388942, "BENLYSTA": 1.7197821141053975, "BETMIGA": 1.4974205544098678, "BEXSERO": 1.2071023568967618, "BIKTARVY": 0.4685120478937855, "BOCEPREVIR": 1.9940130196491517, "BONVIVA": 1.5371178702366926, "BOTULINUM": 23.804227397927736, "BRIDION": 0.938247299365752, "BRILIQUE": 0.336224769750353, "BRINTELLIX": 0.6077920014801902, "BUDESONIDE": 0.5315847114528331, "BYDUREON": 0.7715024627593124, "BYETTA": 0.2189438572793537, "CELECOXIB": 0.4249983220606708, "CELLCEPT": 0.2656631432780393, "CHAMPIX": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1144.json
index 7ce4e71f2bb..7a073d587e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1144.json
@@ -1 +1 @@
-{"COVID19": 3.60503979279196, "GARDASIL": 5.465525774160485, "SPIKEVAX": 13.544281500525624}
\ No newline at end of file
+{"OPDIVO": 78.15567788188058, "null": 0.5979397031702495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11440.json
new file mode 100644
index 00000000000..6bbb43a3346
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11440.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.5393064489756652, "BETMIGA": 7.483972351985338, "BRIDION": 3.497896514802358, "CHAMPIX": 1.1844220387888802, "CIMZIA": 0.3131220273076166, "COMIRNATY": 1.1753328561259695, "COSENTYX": 0.9464949970342637, "ENTRESTO": 0.6009903621418354, "EYLEA": 4.1145403463604495, "GARDASIL": 0.7900650390029503, "IKERVIS": 40.99568776187496, "KEPPRA": 0.3377471560927562, "MEPOLIZUMAB": 0.8864665468421689, "MMRVAXPRO": 1.1432360068236933, "NEVANAC": 17.288658040971523, "NIMENRIX": 1.8433223967594483, "NUCALA": 1.2632597338239635, "PEGASYS": 0.3282484430619026, "SHINGRIX": 1.052228910939003, "SPIKEVAX": 0.9688314295797268, "STELARA": 0.5250139865441461, "SUTENT": 1.6575207976585813, "TAMIFLU": 1.022366225432736, "TOZINAMERAN": 1.5728923851595, "VAXZEVRIA": 0.6756979210787298, "XOLAIR": 2.02944239045929, "null": 1.7505923468177764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11441.json
new file mode 100644
index 00000000000..54fd84aaf19
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11441.json
@@ -0,0 +1 @@
+{"COSENTYX": 193.83357637369545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11442.json
new file mode 100644
index 00000000000..49a043da213
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11442.json
@@ -0,0 +1 @@
+{"ENBREL": 663.2472231461189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11443.json
new file mode 100644
index 00000000000..eb60c321046
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11443.json
@@ -0,0 +1 @@
+{"ABATACEPT": 19.682559956983248, "ADALIMUMAB": 25.498398352245296, "APREMILAST": 130.637047524376, "ARAVA": 49.967261045310735, "CIMZIA": 5.766303692818595, "COSENTYX": 6.278772036764746, "HUMIRA": 8.040641780030887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11444.json
new file mode 100644
index 00000000000..e5aaa3c37a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11444.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11445.json
new file mode 100644
index 00000000000..0cb3d434379
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11445.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 449.0155212501732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11446.json
new file mode 100644
index 00000000000..240995c231f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11446.json
@@ -0,0 +1 @@
+{"null": 1.5291260004714078}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11447.json
new file mode 100644
index 00000000000..8f36a108a6a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11447.json
@@ -0,0 +1 @@
+{"BUPIVACAINE": 71.43084091054347, "COMIRNATY": 0.1337592413212515, "PANTOPRAZOLE": 36.51606075627482, "null": 3.346816397495116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11448.json
new file mode 100644
index 00000000000..db615c21062
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11448.json
@@ -0,0 +1 @@
+{"null": 2.855567181876348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11449.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11449.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1145.json
index a409e1796c0..110c2fa16ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1145.json
@@ -1 +1 @@
-{"ACLIDINIUM": 13.871090054510477, "ANAKINRA": 3.0208704222921985, "APIXABAN": 79.42991019491899, "ARANESP": 8.900080268313706, "AUBAGIO": 2.0227607119696995, "BENLYSTA": 2.617379042781179, "BOSULIF": 2.656398791225277, "BUDESONIDE": 13.25760628901097, "CAPECITABINE": 1.5833264384086485, "CELLCEPT": 1.198473151721349, "DABRAFENIB": 9.799284165527297, "DAXAS": 50.85673159442715, "ELIQUIS": 3.171667260432708, "ENTYVIO": 1.701099603687903, "ESOMEPRAZOLE": 3.846413447961888, "FAMPYRA": 5.662800251634595, "FASLODEX": 1.7492547997394257, "FILGRASTIM": 5.862678694532354, "FLUTICASONE": 18.67924723638552, "FORSTEO": 2.070895571845993, "IBRANCE": 9.42028648752632, "IMATINIB": 7.181520238101033, "INLYTA": 1.7648898029483742, "JAKAVI": 2.0883559371075444, "KISQALI": 3.143046533979188, "LYNPARZA": 2.445219008354557, "MEPOLIZUMAB": 5.704911127696822, "METHOTREXATE": 2.061911351679701, "NEULASTA": 2.6430905838124468, "NUCALA": 5.777465402095108, "OMALIZUMAB": 3.872188813681152, "PEGASYS": 2.8223681388621675, "PEGINTRON": 1.3270101751726513, "PLEGRIDY": 8.553530656642462, "RINVOQ": 1.6832641562513242, "ROACTEMRA": 1.2499610996960682, "RUBRACA": 8.182961645812316, "SIMPONI": 3.847122215484749, "SOLIRIS": 1.8143240840305088, "SPRYCEL": 1.9457336508993357, "SUTENT": 2.342002291788698, "TASIGNA": 1.4833735575663811, "VENCLYXTO": 9.50939809993904, "VFEND": 1.2264385019281647, "XELJANZ": 2.919178973710866, "XOFIGO": 11.552122865732096, "XOLAIR": 1.398651760722725}
\ No newline at end of file
+{"ABACAVIR": 2.074002188302761, "ABATACEPT": 23.446222938073245, "ADALIMUMAB": 19.820134085846625, "AIMOVIG": 1.3458417348794456, "AMINOSALICYLIC": 1.5936323875179308, "APREMILAST": 17.645462022278814, "APREPITANT": 8.58288867959757, "ARAVA": 4.121786791602451, "BENLYSTA": 0.7038372649137203, "BUDESONIDE": 0.3907349892774959, "CIMZIA": 0.2736264375670508, "COMIRNATY": 0.8466755880572606, "COSENTYX": 1.1563560489364415, "CYMBALTA": 0.4211706724895003, "ELIQUIS": 0.3185811204670955, "FASENRA": 1.5824994061187725, "FIRDAPSE": 2.866852161161946, "GARDASIL": 9.804258908793251, "HUMALOG": 0.4869281795209846, "HUMIRA": 0.9284015237295274, "IBUPROFEN": 0.979102750172116, "INLYTA": 1.2807509569689564, "IPILIMUMAB": 1.4477436805268251, "KEPPRA": 0.4005261034087389, "KEYTRUDA": 1.485609393414978, "LACOSAMIDE": 1.8724300831733092, "LANTUS": 0.2038221584016072, "LEMTRADA": 2.3888378570371747, "MYCOPHENOLATE": 4.464571586242477, "OMALIZUMAB": 1.3067060183659551, "PEGASYS": 0.8416210915957152, "PEGINTRON": 1.276740181758285, "PROLIA": 9.30614159252814, "RINVOQ": 2.5378324857900827, "RITUXIMAB": 0.6511544937883886, "SHINGRIX": 1.2439306671248616, "SIMPONI": 0.4196755655161727, "SOLIRIS": 0.6199534280780932, "SPIKEVAX": 0.556097972499292, "TOZINAMERAN": 2.0370631748293726, "TWINRIX": 2.7644421847759544, "VAXZEVRIA": 0.2984471423007727, "XELJANZ": 1.8319657227765065, "XOLAIR": 1.1166542728062885, "ZOSTAVAX": 2.837894299558909, "null": 0.3226938232176149}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11450.json
new file mode 100644
index 00000000000..49fff720fe8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11450.json
@@ -0,0 +1 @@
+{"null": 2.131352186732047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11451.json
new file mode 100644
index 00000000000..75436258ca8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11451.json
@@ -0,0 +1 @@
+{"ABILIFY": 14.377981536510662, "ACLIDINIUM": 75.6748400105427, "BENLYSTA": 7.714755378697043, "CICLOSPORIN": 2.950359752513209, "COMIRNATY": 0.5310954717273509, "COSENTYX": 9.197166413769205, "FASENRA": 18.191868498232004, "MEPOLIZUMAB": 15.55784842889915, "NUCALA": 4.962793229381355, "SOLIRIS": 8.442018520477573, "SPIKEVAX": 0.2795746525038018, "VAXZEVRIA": 0.1806050792728332, "XELJANZ": 1.8522681631377111, "XOLAIR": 3.3462164605735776, "null": 1.164188027717688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11452.json
new file mode 100644
index 00000000000..e6f925ac534
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11452.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 0.270311040732591, "ABATACEPT": 0.0559436993221573, "ABILIFY": 0.4158669957531448, "ACLASTA": 1.4808963979606315, "ACTRAPID": 0.5760699565673487, "ADALIMUMAB": 0.1471516153458071, "ADCIRCA": 2.6540463163284045, "ADEMPAS": 1.1233697390373203, "AERIUS": 0.6760140524973616, "AFINITOR": 0.1121943873110823, "AIMOVIG": 0.4338097913482766, "ALDARA": 0.4368192302154787, "ALEMTUZUMAB": 0.0943385084439639, "ALIMTA": 0.3230354148965319, "ALISKIREN": 0.7148673276530999, "AMBIRIX": 4.986048457054526, "AMBRISENTAN": 1.6972814860104553, "AMINOSALICYLIC": 0.1450944121278507, "ANAKINRA": 2.273249956759648, "ANORO": 0.1859496700819753, "APIDRA": 0.8567653330436821, "APIXABAN": 0.2796746899281916, "APROVEL": 0.7463933690362586, "ARANESP": 0.2194616067053754, "ARAVA": 0.0764391867688051, "ARIPIPRAZOLE": 0.1997223278411334, "ASPARAGINASE": 0.0843445914554857, "ATAZANAVIR": 0.1457559888929595, "ATRIPLA": 0.010846905971555, "AUBAGIO": 0.1713591878808837, "AVAMYS": 0.1177004686790206, 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0.1559763078901603, "RYBELSUS": 0.4603840195514206, "SAXENDA": 1.054447973710941, "SHINGRIX": 1.3695310901798057, "SIFROL": 1.2028589595477837, "SILDENAFIL": 1.7370761569530948, "SILGARD": 5.98697831457964, "SILODOSIN": 6.064983345005123, "SILODYX": 2.897434440441335, "SIMPONI": 0.2773324815529712, "SOLIRIS": 0.3038672218699427, "SOVALDI": 0.5010689632387364, "SPIKEVAX": 1.444835046354639, "SPIRONOLACTONE": 1.9007960643141648, "SPRYCEL": 0.2375361557363201, "STALEVO": 0.6853855857764934, "STELARA": 0.4978331247257475, "STRIBILD": 0.0472357553371753, "SUBOXONE": 0.1815941576227692, "SUTENT": 0.3601898622846264, "SYCREST": 1.9953857093646183, "TAFAMIDIS": 8.648516371117791, "TAGRISSO": 0.1814087008932859, "TAMIFLU": 0.7164470610208314, "TASIGNA": 0.3347057620750182, "TELMISARTAN": 1.6287530093190048, "TERIPARATIDE": 0.8403687648928183, "TESTOSTERONE": 0.3749943275654759, "THALIDOMIDE": 1.0500048762924024, "TICAGRELOR": 0.8904305142127695, "TOUJEO": 0.3435817260103522, "TOVIAZ": 0.722075872620743, "TOZINAMERAN": 2.347251733727326, "TRACLEER": 1.7171148450777345, "TRELEGY": 0.2028965680097053, "TREMFYA": 0.1752766874095951, "TRULICITY": 0.6487471017979329, "TRUMENBA": 22.356207884281368, "TWINRIX": 2.4405646686967493, "UROREC": 3.772687754660724, "VALSARTAN": 1.3963439486729083, "VAXZEVRIA": 0.915821403704618, "VFEND": 0.1572049586587959, "VIAGRA": 1.5587759783710715, "VICTOZA": 0.4299081399869347, "VILDAGLIPTIN": 4.616215246906478, "VIMPAT": 0.8005606299260064, "VOTRIENT": 0.1710709322930928, "XALKORI": 0.3390725320858101, "XARELTO": 0.7362074947847916, "XELJANZ": 0.1784516842501232, "XELODA": 0.320460581439166, "XOLAIR": 0.8465586256024886, "XTANDI": 0.3608032055571961, "XYREM": 0.3215996593887856, "ZARZIO": 2.1982764490824165, "ZOSTAVAX": 0.3067707314669685, "ZYPADHERA": 1.3570606018301783, "ZYPREXA": 0.9826241796700026, "null": 1.0797319326636052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11453.json
new file mode 100644
index 00000000000..90cf01ff214
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11453.json
@@ -0,0 +1 @@
+{"METHOTREXATE": 6.55550587207201, "null": 3.9691444599533514}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11454.json
new file mode 100644
index 00000000000..f45524a2e2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11454.json
@@ -0,0 +1 @@
+{"null": 2.790893158746566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11455.json
new file mode 100644
index 00000000000..48124d08a9f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11455.json
@@ -0,0 +1 @@
+{"ANAKINRA": 8.51183343765308, "ARAVA": 3.838625189221717, "ATRIPLA": 0.744045967364981, "BUDESONIDE": 2.0983367163542326, "CIMZIA": 1.4704055885892064, "COMIRNATY": 0.6708403303274919, "COSENTYX": 4.072452326504733, "CYMBALTA": 0.8374569055469739, "HARVONI": 10.089949488553408, "IBRANCE": 1.5374710412822867, "IBUPROFEN": 5.268481860816761, "LEFLUNOMIDE": 12.24612879296354, "OZEMPIC": 37.64871211772977, "SIMPONI": 3.769085851871375, "SPIKEVAX": 0.7500789815992187, "SUTENT": 0.8145957842212223, "TOZINAMERAN": 0.7012470767215163, "VAXZEVRIA": 0.3271001018850495, "XELJANZ": 7.05331859796084, "ZOSTAVAX": 6.313157955401689, "null": 0.5935699756235815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11456.json
new file mode 100644
index 00000000000..c67014c5a0c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11456.json
@@ -0,0 +1 @@
+{"ARAVA": 2.495508428723587, "COSENTYX": 20.434474237501384, "EMPAGLIFLOZIN": 192.74945276491692, "ENBREL": 32.93021528612962, "null": 0.40485381406118}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11457.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11457.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11458.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11458.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11459.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11459.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1146.json
index c2fe83c015f..6500b17d88b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1146.json
@@ -1 +1 @@
-{"SPIKEVAX": 27.38759860677889}
\ No newline at end of file
+{"COMIRNATY": 0.5019925012985302, "GARDASIL": 27.682357980940907, "VAXZEVRIA": 0.9393081827840992, "null": 0.1996297637353317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11460.json
new file mode 100644
index 00000000000..2d0645982b5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11460.json
@@ -0,0 +1 @@
+{"null": 7.222888890540269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11461.json
new file mode 100644
index 00000000000..6bd8b0e1018
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11461.json
@@ -0,0 +1 @@
+{"null": 0.8825139090080125}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11462.json
new file mode 100644
index 00000000000..ad0cf314a5e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11462.json
@@ -0,0 +1 @@
+{"null": 1.0779278232542049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11463.json
new file mode 100644
index 00000000000..5478f9a3de4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11463.json
@@ -0,0 +1 @@
+{"UPADACITINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11464.json
new file mode 100644
index 00000000000..97b2c5b2abe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11464.json
@@ -0,0 +1 @@
+{"ABATACEPT": 10.2532646246841, "ADALIMUMAB": 10.901069484591602, "AMGEVITA": 45.02311945131504, "ANAKINRA": 13.7823836863213, "APREMILAST": 4.9177431661289726, "ARAVA": 41.80176238718369, "ARIPIPRAZOLE": 1.1432767007230766, "AZATHIOPRINE": 4.106817788563889, "BUDESONIDE": 1.075916862212836, "CELLCEPT": 0.3959624477745031, "CERTOLIZUMAB": 16.266676474083628, "CICLOSPORIN": 1.9341632937986288, "CIMZIA": 13.660353744180268, "COMIRNATY": 0.0603339027286105, "COSENTYX": 6.592732543177906, "CYMBALTA": 0.8589600975723605, "EMPAGLIFLOZIN": 2.824049319653149, "ENBREL": 29.535440842173998, "ENTYVIO": 0.6850380300265633, "ERELZI": 35.24736709455156, "ETANERCEPT": 7.276048476802377, "GARDASIL": 0.2858926153439366, "HUMIRA": 12.242521844973458, "IBUPROFEN": 0.6969114354851107, "IPILIMUMAB": 0.9507762743863264, "KEYTRUDA": 0.1287657661602329, "LEFLUNOMIDE": 14.29554955806094, "METHOTREXATE": 4.436647745167683, "RINVOQ": 4.205473027920404, "RITUXIMAB": 2.611959621425908, "ROACTEMRA": 0.8570748876412577, "SIMPONI": 0.8164295096668591, "SPIKEVAX": 0.0233535693919325, "STELARA": 0.2193857226768051, "TOZINAMERAN": 0.1240833318938182, "VAXZEVRIA": 0.0369007631900015, "XELJANZ": 2.1972923458187, "null": 0.1613299065419306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11465.json
new file mode 100644
index 00000000000..6a3cb832df9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11465.json
@@ -0,0 +1 @@
+{"ATRIPLA": 1.7314611353482163, "BIKTARVY": 36.58830183238787, "COMIRNATY": 0.1817967239664976, "DESCOVY": 116.42312442563582, "SIMPONI": 8.443390340947678, "TRUVADA": 4.282063284253092, "null": 0.1483620397922813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11466.json
new file mode 100644
index 00000000000..a459ef8dbef
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11466.json
@@ -0,0 +1 @@
+{"GENVOYA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11467.json
new file mode 100644
index 00000000000..c806c2b5a93
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11467.json
@@ -0,0 +1 @@
+{"AIMOVIG": 7.01220561846832, "CIMZIA": 4.411717638769053, "COSENTYX": 2.7146593513551784, "DUPIXENT": 37.55296402332177, "EYLEA": 28.84730945603805, "MENVEO": 17.302810662372657, "MMRVAXPRO": 4.106476847441487, "PEGASYS": 0.8165536957877767, "ROACTEMRA": 11.568056652977203, "SIMPONI": 22.933730773841766, "SOMAVERT": 158.79809861795198, "STELARA": 58.23415600419675, "TREMFYA": 36.80699741563749, "TWINRIX": 9.7562749112094, "XOLAIR": 4.5638630696758895, "null": 1.2781781944972832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11468.json
new file mode 100644
index 00000000000..0d01dca2b38
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11468.json
@@ -0,0 +1 @@
+{"CELECOXIB": 124.53901351863097, "null": 1.3434621626054035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11469.json
new file mode 100644
index 00000000000..3a9d0cf08cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11469.json
@@ -0,0 +1 @@
+{"null": 2.118328606160788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1147.json
index 06c7d559de6..59dd24e2071 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1147.json
@@ -1 +1 @@
-{"VIAGRA": 40.49493697391148, "null": 2.7371621301886218}
\ No newline at end of file
+{"ALEMTUZUMAB": 53.86417069725539, "ARANESP": 1.7874672063923678, "BEVACIZUMAB": 2.579597251181986, "BUSULFAN": 14.25040547493326, "CICLOSPORIN": 10.633292758061009, "COMIRNATY": 0.3367824947224919, "ELIQUIS": 0.4942845762277549, "ENTYVIO": 2.623675306513313, "GARDASIL": 0.5696896235492219, "HUMAN": 14.196080412902733, "IPILIMUMAB": 13.880022687975002, "JAKAVI": 3.058782412542934, "KEYTRUDA": 6.385255743966497, "LEMTRADA": 18.532482943166645, "LEVOFLOXACIN": 2.258233611589888, "MABCAMPATH": 57.82679205829911, "NOVONORM": 21.04589928996799, "OPDIVO": 4.155068233475303, "PEGASYS": 5.221186678051403, "PEGINTERFERON": 8.787393852965156, "PEGINTRON": 4.711918642980698, "PEMBROLIZUMAB": 11.952697636026326, "PRIVIGEN": 3.66211384624402, "RIBAVIRIN": 3.329684294857318, "RITUXIMAB": 4.595972321829091, "SOLIRIS": 1.51141942691087, "SPIKEVAX": 0.2405705785712041, "TAMIFLU": 2.522531017769136, "TOZINAMERAN": 0.7567281859346524, "VAXZEVRIA": 0.0905173251939484, "VENCLYXTO": 33.438318546870654, "VENETOCLAX": 35.89574560852182, "null": 0.845120438908757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11470.json
new file mode 100644
index 00000000000..c83d0e6c6e9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11470.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 10.944273074655358, "AMIKACIN": 44.04506161520125, "ASPARAGINASE": 9.784858006065411, "AZACITIDINE": 26.5420189444426, "BEVACIZUMAB": 7.623223702245429, "BUSULFAN": 11.363384083501405, "CANCIDAS": 44.726845426116746, "CASPOFUNGIN": 100.571596874052, "CICLOSPORIN": 7.597134188710917, "CUBICIN": 12.551754928045783, "CYTARABINE": 16.958757636291455, "DEXAMETHASONE": 6.774576681582499, "ECULIZUMAB": 218.76541966221316, "FORXIGA": 6.441921561523345, "JARDIANCE": 6.173832528950668, "NOXAFIL": 33.47062391872174, "VORICONAZOLE": 26.521956508645875, "YESCARTA": 15.470756552538058, "null": 0.6970396910702777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11471.json
new file mode 100644
index 00000000000..a0a0160b3d2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11471.json
@@ -0,0 +1 @@
+{"KEPPRA": 6.3141714168406, "null": 1.19552103395271}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11472.json
new file mode 100644
index 00000000000..34a74508d85
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11472.json
@@ -0,0 +1 @@
+{"BUSULFAN": 4.750479491432523, "CELLCEPT": 2.7091278852798126, "CICLOSPORIN": 1.098572302289463, "CLOPIDOGREL": 2.803490975491928, "COMIRNATY": 0.3531617640835806, "COTELLIC": 12.000473504775988, "CUBICIN": 8.867362060286055, "CYMBALTA": 0.7008465658861003, "CYTARABINE": 3.004391599369833, "IBUPROFEN": 2.6127369136782645, "INSULIN": 3.1069565454960104, "INVOKANA": 30.685230243135727, "JARDIANCE": 1.6077700918634483, "KEYTRUDA": 1.7367208804732914, "LEVETIRACETAM": 8.421576799876128, "MEKINIST": 3.8730848471667856, "SPIKEVAX": 0.5374048240404741, "TOZINAMERAN": 0.8287602864725024, "VAXZEVRIA": 0.110895230609503, "null": 0.8887176055091034}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11473.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11473.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11474.json
new file mode 100644
index 00000000000..d61d4e2fd5a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11474.json
@@ -0,0 +1 @@
+{"ABATACEPT": 6.674290346891963, "ACLIDINIUM": 1.6990409899318126, "ADALIMUMAB": 12.650264122747526, "AIMOVIG": 0.4838320256536505, "APIXABAN": 0.2625230834956244, "APREMILAST": 2.329742859258386, "ARAVA": 50.23302882403277, "ATRIPLA": 0.029587121866067, "AZATHIOPRINE": 2.363334129021855, "BELIMUMAB": 12.792718898788204, "BENLYSTA": 50.11757263885596, "BETAFERON": 0.8353621240598226, "BUPRENORPHINE": 0.2029291309203112, "CELLCEPT": 1.1322151060379837, "CICLOSPORIN": 0.303609845399983, "CIMZIA": 3.4536355867660995, "CLOPIDOGREL": 0.1625789474180734, "COMIRNATY": 0.0951983881685808, "COSENTYX": 0.952341532397206, "CYMBALTA": 0.2434753108708867, "DEXAMETHASONE": 0.1615586771143567, "ELIQUIS": 0.1901123331059252, "ENBREL": 1.3033716828541395, "ENTRESTO": 0.1461396209184366, "ENTYVIO": 0.2333437594571263, "FORSTEO": 0.1677254227866396, "GARDASIL": 1.8158606101894503, "HIZENTRA": 1.251530900828956, "HUMALOG": 0.4184657170996159, "HUMAN": 0.5353046913335482, "HUMIRA": 2.346277825796239, "HYDROCHLOROTHIAZIDE": 4.660739266470458, "IBRANCE": 0.0987203865723686, "INSULIN": 0.2385929637544538, "KEPPRA": 0.4486003667707912, "KEYTRUDA": 0.1821674035567885, "LANTUS": 0.1169947153875812, "LEFLUNOMIDE": 1.3239678131696326, "LUPKYNIS": 24.51061087989994, "LYRICA": 0.4418512399688138, "METHOTREXATE": 0.4918676736004875, "MICARDIS": 0.4704002335291927, "MYCOPHENOLATE": 0.5708123339173818, "NPLATE": 1.0580604351792484, "OMALIZUMAB": 0.389168983307983, "OPSUMIT": 0.9271027577669728, "PEGASYS": 0.5608725266246557, "PEGINTRON": 0.808035844677192, "PEMBROLIZUMAB": 0.4134748826722553, "REMICADE": 0.9859228989196664, "REVATIO": 0.7496107142350994, "RITUXIMAB": 0.876480830045206, "ROACTEMRA": 0.5924340091229761, "SHINGRIX": 0.3120916748122734, "SIMPONI": 1.561327595738668, "SOLIRIS": 0.6791416249474445, "SPIKEVAX": 0.0697694461401199, "STELARA": 0.686005413648489, "SUBOXONE": 0.8436300979077674, "TOZINAMERAN": 0.362181801337557, "TRACLEER": 0.4499797022947773, "TRELEGY": 0.3419969897247902, "TREMFYA": 0.9076554015796348, "TWINRIX": 0.718024202318768, "VAXZEVRIA": 0.0438234697626213, "VIAGRA": 0.2222583091768567, "XELJANZ": 1.173023278410408, "XOLAIR": 0.7119123510924869, "ZOSTAVAX": 0.3996458437428857, "ZYPREXA": 0.110305154411242, "null": 0.3053903809966254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11475.json
new file mode 100644
index 00000000000..9344c2c86fa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11475.json
@@ -0,0 +1 @@
+{"ABATACEPT": 8.64290427068908, "ARAVA": 47.50555943343338, "BENLYSTA": 19.345375212279126, "STELARA": 2.9700677009129333, "null": 0.4760530474759351}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11476.json
new file mode 100644
index 00000000000..7041f4e3460
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11476.json
@@ -0,0 +1 @@
+{"null": 0.6598614144250611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11477.json
new file mode 100644
index 00000000000..ac2ed7b54c2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11477.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 18.281829632326176, "BASILIXIMAB": 73.45076368504093, "BUDESONIDE": 36.288329716460815, "CANCIDAS": 88.36836651328377, "CARMUSTINE": 76.24867406233687, "CASPOFUNGIN": 97.9650393519305, "CICLOSPORIN": 10.426146845235802, "CYTARABINE": 11.018346918548264, "DEXAMETHASONE": 6.418753756799656, "GANCICLOVIR": 27.389445312530945, "NOXAFIL": 60.837678206015845, "POSACONAZOLE": 157.89058464323432, "VENETOCLAX": 124.90642388616382, "null": 0.2375650306385395}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11478.json
new file mode 100644
index 00000000000..375a306c3cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11478.json
@@ -0,0 +1 @@
+{"ADCIRCA": 81.24768652958652, "CELLCEPT": 10.552082865221465, "COMIRNATY": 0.5753484611355589, "DOCETAXEL": 38.20877824310973, "OPSUMIT": 15.17196759879407, "TRACLEER": 35.71621698934188, "null": 0.6184296078897344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11479.json
new file mode 100644
index 00000000000..dcd3a309bc0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11479.json
@@ -0,0 +1 @@
+{"null": 1.343803880076574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1148.json
index 97b52f690a2..5f6415c23cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1148.json
@@ -1 +1 @@
-{"ABACAVIR": 1.9895377867272732, "APIDRA": 4.174941701338904, "LYRICA": 3.075390502789265, "SUBOXONE": 7.850343356141138, "TESTOSTERONE": 86.29151750289886, "VIAGRA": 27.847725306035787, "null": 3.791160273071851}
\ No newline at end of file
+{"ARAVA": 0.4581513374314941, "ATRIPLA": 0.3189812430266722, "AZATHIOPRINE": 1.9389039653071436, "BETAFERON": 11.16210432686378, "CELLCEPT": 2.1963496160591047, "CICLOSPORIN": 0.7715922786801394, "CIMZIA": 0.8996992694406093, "COMIRNATY": 0.5196302407774825, "EFAVIRENZ": 24.95958915522084, "ELIQUIS": 0.7798892386677392, "ENTYVIO": 1.382361106277633, "GARDASIL": 0.4775089836896715, "HARVONI": 3.150997217739466, "HUMIRA": 1.277236341784619, "IBUPROFEN": 1.670128794968842, "INLYTA": 2.383035737460913, "IPILIMUMAB": 51.54027169247216, "IRBESARTAN": 4.1307925051756245, "KAFTRIO": 3.849611794023478, "KEPPRA": 0.6832099523861335, "KEYTRUDA": 14.567260185171154, "KISQALI": 4.662140448474119, "LEMTRADA": 7.080337086155354, "NIVOLUMAB": 17.700799856520298, "OPDIVO": 26.58098832801254, "PEGASYS": 4.425602181478599, "PEGINTERFERON": 12.574081858862918, "PEGINTRON": 8.120395641296605, "PEMBROLIZUMAB": 14.372157104986156, "RIBAVIRIN": 4.282821429664738, "SIMPONI": 0.6767852958752886, "SOVALDI": 4.34647692809549, "SPIKEVAX": 0.4163816307393004, "STELARA": 1.1383657960609996, "TOZINAMERAN": 0.6011530400672034, "TRACLEER": 3.228217651011847, "TWINRIX": 4.255827910464643, "VAXZEVRIA": 0.2186527098642224, "VICTOZA": 2.5179543769007697, "YERVOY": 27.81665257726338, "null": 0.6660303060568349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11480.json
new file mode 100644
index 00000000000..8bf367bb239
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11480.json
@@ -0,0 +1 @@
+{"null": 0.8927233659844568}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11481.json
new file mode 100644
index 00000000000..933b60348b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11481.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 44.35671237954451, "AVANDIA": 4.647644783279799, "CLOPIDOGREL": 6.25898486101375, "COMIRNATY": 0.1409727232720918, "ENTRESTO": 11.076860304589946, "IBUPROFEN": 31.049532992731024, "OLANZAPINE": 4.34097442795342, "SPIKEVAX": 0.234814211930954, "null": 0.7804747038559238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11482.json
new file mode 100644
index 00000000000..31946f8e532
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11482.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1701161724256057, "CYMBALTA": 3.3052396672855413, "KEPPRA": 4.1257794434334745, "null": 2.801524754758372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11483.json
new file mode 100644
index 00000000000..ec2943762be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11483.json
@@ -0,0 +1 @@
+{"ANAKINRA": 28.568087594253928, "CICLOSPORIN": 15.024978496783095, "KYMRIAH": 33.08506731837743, "STELARA": 9.616228481105145, "null": 0.6236202149809068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11484.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11484.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11485.json
new file mode 100644
index 00000000000..5704b43280f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11485.json
@@ -0,0 +1 @@
+{"null": 0.8515841511674774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11486.json
new file mode 100644
index 00000000000..84da8c7b6f7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11486.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 96.109955574952, "CYTARABINE": 53.02214639499286, "null": 0.2078308629479064}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11487.json
new file mode 100644
index 00000000000..aaea1e928e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11487.json
@@ -0,0 +1 @@
+{"ATRIPLA": 5.657557063963902, "BUSULFAN": 34.34867236203208, "COMIRNATY": 0.2142193580501621, "LEMTRADA": 50.21609759431973, "null": 0.147722594269878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11488.json
new file mode 100644
index 00000000000..314d0282d57
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11488.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6406635489473061, "null": 0.4309090647495694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11489.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11489.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1149.json
index b8691f2a999..a4bc349472c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1149.json
@@ -1 +1 @@
-{"null": 3.4119142571515}
\ No newline at end of file
+{"ALEMTUZUMAB": 49.79657281407666, "COMIRNATY": 0.2976500751187312, "IPILIMUMAB": 47.27680113505468, "KEYTRUDA": 47.03340135876147, "LEMTRADA": 50.504121548127145, "PEMBROLIZUMAB": 86.86038597547537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11490.json
new file mode 100644
index 00000000000..f4dbb009c7c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11490.json
@@ -0,0 +1 @@
+{"APIXABAN": 64.17304634885492, "CHAMPIX": 1.524086921154436, "COMIRNATY": 0.7492486851271172, "ELIQUIS": 2.4086637374105235, "HUMIRA": 7.189093969818699, "RASILEZ": 10.017809356779676, "SPIKEVAX": 0.3565593492775732, "VAXZEVRIA": 0.3167777879790022, "null": 1.3690230274766266}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11491.json
new file mode 100644
index 00000000000..f9d8586aa73
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11491.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.1535005008618862, "ABATACEPT": 0.0396432207517279, "ABILIFY": 0.8889377438666144, "ACLIDINIUM": 1.5550953950881257, "ACTRAPID": 0.3866586437896327, "ADALIMUMAB": 0.1886961655371956, "ADCIRCA": 0.509897045290078, "ADENURIC": 0.631927513526488, "AERIUS": 2.6379708240277746, "AFINITOR": 0.2025983533526867, "AGOMELATINE": 5.76843848818348, "AIMOVIG": 0.3465066206924146, "ALEMTUZUMAB": 0.7788072527825537, "ALIMTA": 0.1836964030419276, "ALL": 0.640058632205094, "AMIKACIN": 0.4607522133140003, "AMINOSALICYLIC": 0.0715510483248601, "ANAKINRA": 0.2109042706171082, "ANORO": 0.1862059935682942, "APIDRA": 0.1695348016055769, "APIXABAN": 0.3011944345607644, "APROVEL": 0.5854047594122539, "ARANESP": 0.1159840225852321, "ARAVA": 0.042569659467553, "ARIPIPRAZOLE": 1.1308611584918074, "ASPARAGINASE": 0.6584371934177609, "ATAZANAVIR": 0.1338258037591073, "ATOSIBAN": 1.1194616552518066, "ATRIPLA": 0.0044210205696306, "AUBAGIO": 0.2050232368586936, "AVAMYS": 0.0832170471476796, "AVANDIA": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11492.json
new file mode 100644
index 00000000000..6373cd15806
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11492.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1449198753898798, "FENTANYL": 11.790156404907377, "null": 3.425265063164436}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11493.json
new file mode 100644
index 00000000000..561a3e09d26
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11493.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3621671211505262, "null": 3.5632407370537456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11494.json
new file mode 100644
index 00000000000..5689c82dc38
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11494.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.845781140978056, "SPIKEVAX": 0.765320109258483, "VAXZEVRIA": 0.2158658969845804, "null": 1.311174999363507}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11495.json
new file mode 100644
index 00000000000..41900cb1eb8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11495.json
@@ -0,0 +1 @@
+{"ABILIFY": 5.413327830099603, "BRINTELLIX": 14.891530403737285, "CHAMPIX": 6.760559695497684, "COMIRNATY": 0.1128839777374961, "CYMBALTA": 8.359678232335979, "INFLIXIMAB": 35.54190639486685, "LATUDA": 31.770158734798905, "OLANZAPINE": 2.6399098767488387, "SUBOXONE": 7.392749448485248, "TOZINAMERAN": 0.3450015908658996, "VAXZEVRIA": 0.292017282813902, "ZYPREXA": 2.5554383542128964, "null": 2.0420741191258456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11496.json
new file mode 100644
index 00000000000..dfae41c21da
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11496.json
@@ -0,0 +1 @@
+{"MIDAZOLAM": 62.386123568211865, "null": 1.8872694965666417}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11497.json
new file mode 100644
index 00000000000..334371ef7b6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11497.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.5885049861510062, "AFINITOR": 1.209502240001313, "ALEMTUZUMAB": 1.368209129832672, "AMINOSALICYLIC": 0.7112690325759619, "ANAKINRA": 1.172533700961546, "APIXABAN": 0.7665532939033416, "ARAVA": 0.0782265774670076, "ARIPIPRAZOLE": 0.9302140952477492, "ASPARAGINASE": 2.8736869254137347, "ATOSIBAN": 15.338794969603104, "BEDAQUILINE": 2.6936083247663296, "BUDESONIDE": 4.01051007526358, "CASPOFUNGIN": 2.3655419776914144, "CELLCEPT": 1.2183617603700645, "CICLOSPORIN": 1.2815727766249358, "CLOPIDOGREL": 1.6275212555928775, "COMBIVIR": 1.1622166362967172, "COMIRNATY": 0.5121646283347855, "CUBICIN": 3.200440446364244, "CYMBALTA": 0.249824585971147, "CYTARABINE": 1.4401863985354977, "DARZALEX": 7.09790460121499, "DEXAMETHASONE": 4.229537645272105, "DEXMEDETOMIDINE": 18.70687499240957, "DOCETAXEL": 0.9932513992958714, "EFAVIRENZ": 2.3557017322994294, "ELIQUIS": 0.1772319369219063, "ENOXAPARIN": 3.765974249796874, "ENTRESTO": 1.0328706372954646, "EUCREAS": 3.428513890527847, "EXJADE": 0.9987824769465742, "FENTANYL": 1.8963700943394557, "FILGRASTIM": 2.245387301961376, "FLEBOGAMMA": 20.039982720780134, "FORXIGA": 0.7269798485908661, "FUZEON": 34.83688039408922, "GANCICLOVIR": 3.4069424331740854, "GARDASIL": 0.4528444834280342, "HERCEPTIN": 1.7256711529306494, "HUMALOG": 0.4477225190521822, "HUMAN": 3.594470826053608, "HYDROCORTISONE": 1.6704952581038366, "IBUPROFEN": 0.7304344226294486, "INSULIN": 0.8362631857050601, "IRBESARTAN": 3.2763636681178534, "JARDIANCE": 3.239067916915157, "KALETRA": 1.747047878887279, "KEYTRUDA": 0.2239415552895141, "KIOVIG": 6.076616561141799, "KYMRIAH": 7.786120482614289, "LAMIVUDINE": 3.9064763703618426, "LEVOFLOXACIN": 3.2133391386983625, "LYRICA": 0.4626772946815755, "METFORMIN": 2.927355990323285, "METHOTREXATE": 0.3524668390292218, "MIDAZOLAM": 2.624312019975212, "MMRVAXPRO": 0.3334789206745455, "NAGLAZYME": 8.240523315057377, "NUCALA": 0.4668384894506195, "OLANZAPINE": 3.701659954096424, "OMALIZUMAB": 0.5706128643547737, "PEGASYS": 0.1119489712994528, "PLAVIX": 0.8790962016939813, "PRIVIGEN": 12.136740230264456, "RISPERIDONE": 4.637166709491953, "RIVAROXABAN": 4.887118206946417, "SPIKEVAX": 0.2812028568271524, "SPIRONOLACTONE": 2.354324392724259, "SYNAGIS": 5.781712525774465, "TAMIFLU": 1.7570904668543157, "TICAGRELOR": 8.386228561773121, "TOZINAMERAN": 0.7707012922448747, "ULTIBRO": 27.485574182342447, "VALSARTAN": 4.556954985272079, "VAXZEVRIA": 0.1694563154618386, "XOLAIR": 0.702128584421744, "YESCARTA": 3.256417752883764, "ZYPREXA": 1.005346677417834, "null": 2.1809399006569627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11498.json
new file mode 100644
index 00000000000..e4079eb49c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11498.json
@@ -0,0 +1 @@
+{"null": 0.6328555915525093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11499.json
new file mode 100644
index 00000000000..0de98074b29
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11499.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 7.962619640125279, "INFLIXIMAB": 135.00071655905907, "null": 0.6096614320622229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/115.json
index b026472186b..452f1ac5ac7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/115.json
@@ -1 +1 @@
-{"ADENURIC": 374.1761842739554, "null": 1.4863998810893884}
\ No newline at end of file
+{"BUPRENORPHINE": 54.6899067853232, "IBUPROFEN": 14.743583935036874, "null": 3.899592919271087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1150.json
index 2eaa598f27b..3a6b80d1e80 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1150.json
@@ -1 +1 @@
-{"null": 1.53567740245871}
\ No newline at end of file
+{"KEYTRUDA": 45.09308897844004}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11500.json
new file mode 100644
index 00000000000..9a779688168
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11500.json
@@ -0,0 +1 @@
+{"COMBIVIR": 30.08190886333052, "ENOXAPARIN": 6.5458191915383015, "IRON": 16.597253085404695, "KEPPRA": 4.365130968211674, "LEVETIRACETAM": 5.463303368911634, "OLANZAPINE": 2.43979613169876, "STELARA": 0.9862588160626112, "SUBOXONE": 3.210084138230469, "ZYPREXA": 5.520231839178042, "null": 7.111129344162369}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11501.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11501.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11502.json
new file mode 100644
index 00000000000..9e36c29470d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11502.json
@@ -0,0 +1 @@
+{"null": 1.037185294654559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11503.json
new file mode 100644
index 00000000000..b8851f64b00
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11503.json
@@ -0,0 +1 @@
+{"ABILIFY": 26.23340159079271, "ARIPIPRAZOLE": 25.336666325372665, "BREXPIPRAZOLE": 86.4079128185948, "BRINTELLIX": 1.0717970647726618, "BUPRENORPHINE": 1.5861507795365677, "CYMBALTA": 2.1685433181393106, "DULOXETINE": 3.276067342062273, "INVEGA": 54.95648117928224, "KEPPRA": 0.5273311334437972, "LATUDA": 107.3720914635213, "LOXAPINE": 54.984589144793546, "LURASIDONE": 32.6024874450853, "MELATONIN": 5.113644377231088, "OLANZAPINE": 35.108967433302034, "RISPERIDONE": 11.535893240526423, "ZYPADHERA": 5.6349484121202185, "ZYPREXA": 23.68293687485168, "null": 2.522274394430345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11504.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11504.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11505.json
new file mode 100644
index 00000000000..3ef11e9d382
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11505.json
@@ -0,0 +1 @@
+{"null": 0.7816763579197556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11506.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11506.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11507.json
new file mode 100644
index 00000000000..67a7b46a297
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11507.json
@@ -0,0 +1 @@
+{"CELECOXIB": 529.9483074308141, "DEXAMETHASONE": 33.32089572405462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11508.json
new file mode 100644
index 00000000000..858aa84eafc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11508.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 1.1777927450331265, "ABRAXANE": 1.762504258849923, "ADALIMUMAB": 1.0028726270108912, "AFINITOR": 2.7493624911326378, "AIMOVIG": 8.828832460340209, "ALIMTA": 1.0372589041216596, "ANORO": 1.69232676919468, "APIDRA": 0.4079129827105781, "APREMILAST": 7.716361181389326, "ARAVA": 0.0468277826616211, "ATAZANAVIR": 0.9544294723065896, "AUBAGIO": 0.4607516020860081, "AVAMYS": 2.9775636617245675, "AVASTIN": 0.8525789233333254, "AXITINIB": 1.6519727377606743, "BEVACIZUMAB": 0.7134076811017545, "BOCEPREVIR": 3.953089900554972, "BOSULIF": 0.7491425743151158, "BRAFTOVI": 1.320349552498972, "BRINTELLIX": 1.4914194267199017, "BYDUREON": 0.4782070782799623, "BYETTA": 0.5201118073216515, "CABOMETYX": 15.59055012721845, "CELLCEPT": 0.2850126350108979, "CHAMPIX": 2.820162667201814, "CIMZIA": 0.0757444147031308, "CLOPIDOGREL": 0.5332108313466031, "COAPROVEL": 1.0660824291556692, "COMIRNATY": 0.8223697357883949, "COSENTYX": 0.5374087978310153, "CYMBALTA": 0.2274953108061184, "DEXAMETHASONE": 0.3857205174423056, "DOCETAXEL": 1.1063188397781412, "ELIQUIS": 0.3874758129481433, "ENTRESTO": 0.5173618356625014, "ERLEADA": 1.877699424770346, "ESBRIET": 2.500588054247004, "EXFORGE": 0.64587955769589, "EXJADE": 0.564540950678361, "FASENRA": 0.8408732275556947, "FASLODEX": 1.810986789041676, "FENTANYL": 0.1634081245166534, "FORSTEO": 0.5365638989824147, "FORXIGA": 0.538301780638408, "FULVESTRANT": 0.8236201053536178, "GARDASIL": 0.1461175788491019, "HALAVEN": 1.333777124490679, "HERCEPTIN": 1.3229483516821894, "HUMALOG": 0.129286893402472, "IBRANCE": 2.473333381456002, "IBUPROFEN": 0.2864977325583558, "INCIVO": 1.058767952100019, "INLYTA": 2.7504690893114296, "IRBESARTAN": 0.8786065979432185, "IRESSA": 1.72707156489753, "IRINOTECAN": 0.8641409726086644, "JANUMET": 0.2149124787162749, "JANUVIA": 0.2187458473026643, "JARDIANCE": 0.6342955657363689, "JEVTANA": 2.8075736469532875, "KALETRA": 0.3473392926453583, "KEPPRA": 0.5347921425768161, "KEYTRUDA": 1.5223781561265748, "KISQALI": 1.5765887708517177, "LANTUS": 0.47163423688781, "LENVIMA": 1.418304177892722, "LEVETIRACETAM": 0.2093339569660436, "LEVOFLOXACIN": 0.2738759046174894, "LONSURF": 2.652450755374248, "LYNPARZA": 6.617552655954723, "MEKINIST": 0.6240512793297273, "MICARDIS": 0.4183411605173096, "NEULASTA": 0.7448347307574423, "NEXAVAR": 0.6286667171247838, "NINLARO": 1.378009818410408, "OFEV": 2.0028583095256924, "OLANZAPINE": 0.1285168952063905, "OPDIVO": 1.0892933482491185, "OPSUMIT": 0.2283930714368693, "PAZOPANIB": 2.1667296057952354, "PEGASYS": 2.2379391352285785, "PEGINTERFERON": 0.882358536566223, "PEGINTRON": 1.8961140294294971, "PLAVIX": 0.5436247584903624, "RELVAR": 2.424192544424069, "REVLIMID": 1.1057949151823805, "RIBAVIRIN": 0.4684512554898496, "RINVOQ": 0.4168515699536051, "RUBRACA": 5.807960413659807, "RYBELSUS": 3.242731729133689, "SAXENDA": 1.3882153203423788, "SHINGRIX": 0.3302258186577527, "SIMPONI": 0.1286985285474326, "SPIKEVAX": 0.7538734084920603, "SPRYCEL": 0.7347970845145515, "STELARA": 0.1722348343602243, "STIVARGA": 0.3221479297368434, "SUBOXONE": 0.3810755067070228, "SUTENT": 13.1972229528317, "TAGRISSO": 3.310603632309159, "TAMIFLU": 0.92238114602432, "TOVIAZ": 0.9211107613498216, "TOZINAMERAN": 0.7760241993690741, "TRELEGY": 0.9558222176123728, "TRULICITY": 1.3941206618087698, "VAXZEVRIA": 0.8030255919495237, "VICTOZA": 0.5301350239911846, "VOTRIENT": 5.687004959638173, "XALKORI": 6.141023578679089, "XELJANZ": 0.2318339621532484, "XOLAIR": 0.258468674444484, "XTANDI": 3.697972778776074, "ZEJULA": 5.273624866344597, "ZELBORAF": 2.7497857124415304, "null": 1.074107158177304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11509.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11509.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1151.json
index 359feec4961..26ca29c54d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1151.json
@@ -1 +1 @@
-{"TESTOSTERONE": 402.4808588251767, "null": 3.5997300350910018}
\ No newline at end of file
+{"KEYTRUDA": 71.32512663918172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11510.json
new file mode 100644
index 00000000000..31287b171c8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11510.json
@@ -0,0 +1 @@
+{"null": 2.88677152477758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11511.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11511.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11512.json
new file mode 100644
index 00000000000..f4335e789ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11512.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 2.078769239139631, "ATAZANAVIR": 274.49272737447063, "BEXSERO": 12.257345120312715, "BRINTELLIX": 2.1929907249524843, "CHAMPIX": 42.72366678673967, "COMIRNATY": 0.1738510818319967, "CYMBALTA": 1.9399531295414527, "ENFUVIRTIDE": 126.96567792080737, "GARDASIL": 1.2310204471073405, "INSULIN": 2.4207840880843943, "KEPPRA": 0.7607550691937863, "MMRVAXPRO": 2.955086151459067, "NIMENRIX": 5.2838289523440585, "PEGASYS": 0.8772714086752422, "ROTATEQ": 4.29196254850502, "SPIKEVAX": 0.0940890558553631, "TOZINAMERAN": 0.8540530078039019, "VAXZEVRIA": 0.4507804850480922, "null": 1.2002172577073504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11513.json
new file mode 100644
index 00000000000..94eee3275c1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11513.json
@@ -0,0 +1 @@
+{"ATRIPLA": 36.19941505095316, "STRIBILD": 23.07609301873647, "TRUVADA": 13.802859350777782, "null": 0.3586255836325547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11514.json
new file mode 100644
index 00000000000..6b6f6c1c4d9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11514.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8626497817762862, "VAXZEVRIA": 1.9505233814036569, "null": 0.4194736946139901}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11515.json
new file mode 100644
index 00000000000..1d5275f4c15
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11515.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6947162743931646, "COSENTYX": 6.602495231288865, "VAXZEVRIA": 0.7312395505748718, "null": 1.0823243895704162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11516.json
new file mode 100644
index 00000000000..838930734f5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11516.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8939132896903174, "SPIKEVAX": 1.964716490149295, "TOZINAMERAN": 3.689359675250836, "null": 0.2264367431057311}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11517.json
new file mode 100644
index 00000000000..5eded1045ba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11517.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.3309879571468712, "AIMOVIG": 1.3363310463075604, "ATRIPLA": 0.3810988025711483, "AUBAGIO": 4.2858676360619965, "BEVACIZUMAB": 2.581694706057118, "CARBIDOPA": 11.692271088444596, "COMIRNATY": 0.4128708472572127, "DARZALEX": 20.89466903349048, "DEXAMETHASONE": 1.2792261958060942, "DOCETAXEL": 1.93093891721422, "FAMPYRA": 12.002922216637192, "GALAFOLD": 21.084889731617096, "GARDASIL": 2.534298848519278, "HERCEPTIN": 5.6878798243618585, "IBRANCE": 0.8507101655077018, "IRINOTECAN": 4.283016265391968, "KEYTRUDA": 0.8053105493162284, "LATUDA": 2.642258719239546, "LEMTRADA": 14.921472685548324, "LEVOFLOXACIN": 3.8539043084000606, "NEXAVAR": 0.9718495371051934, "OMALIZUMAB": 2.974524826180535, "PEGASYS": 1.6356846606575477, "PEGINTRON": 0.8060846963619029, "PLAVIX": 0.7075847715178094, "PROPRANOLOL": 8.725528961993163, "SPIKEVAX": 0.2944423027520338, "STIVARGA": 2.4642145382163694, "SUTENT": 2.480135351840312, "TOZINAMERAN": 1.3505390896372311, "VAXZEVRIA": 0.4502021534937133, "XELJANZ": 0.7901804900459927, "XOLAIR": 2.987774435861719, "XTANDI": 1.3504483319501286, "ZOSTAVAX": 1.01725791044916, "null": 1.3868128863499285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11518.json
new file mode 100644
index 00000000000..3643e2f03ed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11518.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.0164241005472725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11519.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11519.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1152.json
index 4d17ebfdf82..b20a402adeb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1152.json
@@ -1 +1 @@
-{"null": 1.4303389403425195}
\ No newline at end of file
+{"COMIRNATY": 2.65566004690295, "KEYTRUDA": 26.656553489654563, "SPIKEVAX": 0.8838212574475603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11520.json
new file mode 100644
index 00000000000..3cbc29f2d1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11520.json
@@ -0,0 +1 @@
+{"ABACAVIR": 188.0771604736076, "COMIRNATY": 1.8716044857332472, "CYMBALTA": 0.4234813860422466, "ENBREL": 4.1295037901516976, "GARDASIL": 3.3714104182582108, "HARVONI": 3.95601656254784, "HUMIRA": 4.016110599911016, "HYDROCORTISONE": 8.880705371697477, "MODERNA": 19.86856228141124, "OLANZAPINE": 0.6388808040180364, "ORENCIA": 53.367712192936494, "SHINGRIX": 1.1238252210387925, "SPIKEVAX": 0.7287610023265952, "TOZINAMERAN": 0.4194199878298358, "VAXZEVRIA": 0.6719463441447906, "null": 0.2683638439163621}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11521.json
new file mode 100644
index 00000000000..9d2592bc8d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11521.json
@@ -0,0 +1 @@
+{"RINVOQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11522.json
new file mode 100644
index 00000000000..d40f52dd36a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11522.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 137.07824227255696, "COMIRNATY": 0.1913175653505451, "KEPPRA": 8.619945450302703, "LEVETIRACETAM": 15.916514601487258, "VAXZEVRIA": 0.2868787970512237, "null": 1.523695662988207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11523.json
new file mode 100644
index 00000000000..6ae31a634e6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11523.json
@@ -0,0 +1 @@
+{"LACOSAMIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11524.json
new file mode 100644
index 00000000000..4db21658db0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11524.json
@@ -0,0 +1 @@
+{"ATRIPLA": 1.0449563495553826, "COMIRNATY": 0.9596497779988404, "COSENTYX": 5.053846143796851, "SPIKEVAX": 0.3635614865021567, "TOZINAMERAN": 1.3332808970669747, "VAXZEVRIA": 0.6299248368372609, "ZOSTAVAX": 10.110953286066565, "null": 0.7524476715040155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11525.json
new file mode 100644
index 00000000000..140c2f7c1f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11525.json
@@ -0,0 +1 @@
+{"COSENTYX": 190.2143425005944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11526.json
new file mode 100644
index 00000000000..49a043da213
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11526.json
@@ -0,0 +1 @@
+{"ENBREL": 663.2472231461189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11527.json
new file mode 100644
index 00000000000..7ebbf831587
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11527.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.1155685107496991, "AFINITOR": 1.210199767524856, "AIMOVIG": 0.4676055771810462, "ARAVA": 0.6638258763664316, "ARIPIPRAZOLE": 3.833999900297002, "BYDUREON": 0.8096950084570137, "CICLOSPORIN": 0.8805536184612707, "CLOPIDOGREL": 0.3101108563096653, "COMIRNATY": 1.8819908146350652, "COSENTYX": 3.23350390646102, "CYMBALTA": 0.1026932991777659, "CYTARABINE": 0.4399758048211692, "ELIQUIS": 0.1562008253583886, "ENBREL": 1.5396064406997363, "ENOXAPARIN": 2.290697421537317, "EVEROLIMUS": 2.49096443730201, "FASLODEX": 0.537680490620069, "GARDASIL": 1.07017768781777, "HUMIRA": 0.4598809767309001, "HYDROCORTISONE": 1.349755688534206, "LEFLUNOMIDE": 1.9024395024574257, "LEVOFLOXACIN": 0.7616313503943577, "MEKINIST": 0.6345838003028764, "MENVEO": 1.9169627933702755, "METHOTREXATE": 11.120209532348198, "MODERNA": 1.2503232768422097, "NEXAVAR": 0.2067136930512511, "OCRELIZUMAB": 2.508620157370585, "PANTOPRAZOLE": 1.828020582282719, "SHINGRIX": 2.322517785795833, "SPIKEVAX": 2.418596080556039, "STELARA": 0.6774423064575741, "STIVARGA": 0.6636452554934625, "SUTENT": 0.4557414995092718, "TOZINAMERAN": 1.5152761656273457, "VAXZEVRIA": 4.349460597378979, "XELJANZ": 1.021076123171651, "ZOSTAVAX": 0.5263717123741075, "null": 0.2744954503468229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11528.json
new file mode 100644
index 00000000000..7025ca5f855
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11528.json
@@ -0,0 +1 @@
+{"null": 1.4902151349234876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11529.json
new file mode 100644
index 00000000000..5d68f82ef05
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11529.json
@@ -0,0 +1 @@
+{"null": 0.7485510523650343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1153.json
index 152238733f8..c59565aeb8f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1153.json
@@ -1 +1 @@
-{"IRBESARTAN": 45.9891528125131, "KEYTRUDA": 9.8089966110222, "LEMTRADA": 120.05676553153154, "OPDIVO": 19.05353379167592, "PEGINTRON": 7.516104243376881, "SUTENT": 5.23065625266773}
\ No newline at end of file
+{"IPILIMUMAB": 190.2043671983852, "KEYTRUDA": 31.256939090683133, "OPDIVO": 37.69317824285383, "PEMBROLIZUMAB": 77.25340791481104, "null": 0.1715456222990886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11530.json
new file mode 100644
index 00000000000..b3600654f17
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11530.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6389755972760183, "LEVOFLOXACIN": 32.80587780917739, "SPIKEVAX": 0.7482347448865067, "VAXZEVRIA": 0.2542377134730385, "null": 3.6861934953896687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11531.json
new file mode 100644
index 00000000000..e1b99b55e92
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11531.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.9545245608092408, "APIDRA": 2.7634852465380204, "ARAVA": 1.42741981101263, "CIMZIA": 0.9250489831357952, "COMIRNATY": 0.4801051204102228, "COSENTYX": 3.133870211518992, "ELIQUIS": 0.3403476204083481, "ENBREL": 1.0345284002704824, "FESOTERODINE": 61.27244894001729, "LEFLUNOMIDE": 10.046108271160474, "LEVOFLOXACIN": 27.9730053577854, "OPTIMARK": 3.5843842753130137, "SPIKEVAX": 0.2157747610912475, "TOZINAMERAN": 0.2973194127273949, "VAXZEVRIA": 0.1791967102410732, "XELJANZ": 1.7515830718856935, "null": 2.9989381171698795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11532.json
new file mode 100644
index 00000000000..9ca356e9909
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11532.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.0502958261796183, "COSENTYX": 1.7412907479644797, "LANTUS": 0.6948240182295012, "LEVOFLOXACIN": 20.83143110972921, "SIMPONI": 1.601401862789199, "SPIKEVAX": 0.0762526613784536, "TOZINAMERAN": 0.2089860868074708, "VAXZEVRIA": 0.0641985363630741, "XELJANZ": 1.014718244606839, "null": 7.4833321416555805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11533.json
new file mode 100644
index 00000000000..810ba4fdfba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11533.json
@@ -0,0 +1 @@
+{"null": 0.5500856115978128}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11534.json
new file mode 100644
index 00000000000..167ad9fb0f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11534.json
@@ -0,0 +1 @@
+{"ARAVA": 0.1947473558480275, "CIMZIA": 3.077473754607861, "COMIRNATY": 0.693803235672703, "COSENTYX": 0.8517805601593268, "LEVOFLOXACIN": 50.71165734159992, "SPIKEVAX": 0.4782201521691701, "SUTENT": 0.283301133149839, "TOZINAMERAN": 0.4440536663116373, "VAXZEVRIA": 0.32329701125223, "null": 3.378781795831944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11535.json
new file mode 100644
index 00000000000..1581f0329d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11535.json
@@ -0,0 +1 @@
+{"AIMOVIG": 0.385331167310954, "APIDRA": 0.6728911132065992, "ARAVA": 0.1948182308512833, "ARIXTRA": 7.886298648816006, "ATRIPLA": 0.2083989784031001, "CICLOSPORIN": 0.4066991460410818, "CIMZIA": 0.2180866562260349, "COLLAGENASE": 179.28475633377508, "COMIRNATY": 0.0598111480674291, "CORTICOSTEROID": 43.48819364805213, "CORTICOSTEROIDS": 38.47378654180518, "COSENTYX": 0.4504347603375168, "CYMBALTA": 0.2165137800039495, "DEXAMETHASONE": 0.8625337317906653, "ELIQUIS": 0.2944652403718666, "ENBREL": 0.6579639512056361, "FORSTEO": 0.910948968331704, "HUMIRA": 1.7160106836247904, "JANUVIA": 0.4912341949594896, "LANTUS": 0.5001245605959633, "LEVOFLOXACIN": 40.72473996524023, "PLAVIX": 0.2530091506747218, "ROACTEMRA": 0.7072405873803252, "SIMPONI": 1.6373457406655691, "SPIKEVAX": 0.0262080126945342, "STELARA": 0.4749913195037498, "TOZINAMERAN": 0.1408515237630082, "TRUVADA": 0.191688749525244, "VAXZEVRIA": 0.0641635034461912, "XELJANZ": 1.5710574952248415, "XIAPEX": 100.7051940880498, "XOLAIR": 0.4694323249833418, "null": 6.522948106279165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11536.json
new file mode 100644
index 00000000000..a98eee6f4e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11536.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.5157551354240177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11537.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11537.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11538.json
new file mode 100644
index 00000000000..990f89931bf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11538.json
@@ -0,0 +1 @@
+{"ALL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11539.json
new file mode 100644
index 00000000000..b24db45b797
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11539.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.2895370950725321, "ADALIMUMAB": 0.6515196889435164, "AIMOVIG": 0.4482529438576074, "AMGEVITA": 91.50465489607292, "ARAVA": 0.0592933234752833, "ARIPIPRAZOLE": 0.4760859836024855, "ATRIPLA": 0.0841948732206723, "AUBAGIO": 0.53519119774761, "BENLYSTA": 0.7301743285900147, "BUDESONIDE": 0.2525380416829946, "CELLCEPT": 0.546931831008094, "CIMZIA": 0.5263003320580725, "CLOPIDOGREL": 0.2683520925784882, "COMIRNATY": 0.4619693940981069, "COSENTYX": 2.471719031473881, "CYMBALTA": 2.7338438088382557, "DULOXETINE": 1.1556617191582867, "ELIQUIS": 0.2440251633765119, "EMPAGLIFLOZIN": 3.5214035165709885, "ENBREL": 0.6254578773818665, "FORSTEO": 0.484704116295999, "GARDASIL": 0.634455729041063, "HUMALOG": 0.2480985502994971, "HUMIRA": 1.0192336193333429, "HYDROCORTISONE": 3.44702652238286, "IBUPROFEN": 0.8016395230579706, "JANUVIA": 0.5158476681760645, "KEPPRA": 0.3555039435702778, "LANTUS": 0.2589721717790712, "LEFLUNOMIDE": 3.6759919871292, "LEVOFLOXACIN": 45.88546836349259, "METHOTREXATE": 0.4492880141271995, "MICARDIS": 2.7736174320764237, "MODERNA": 0.4181655496226616, "PEGASYS": 0.1736632276993377, "SHINGRIX": 0.3088211699838907, "SIMPONI": 0.894254864087914, "SOMAVERT": 21.905398881491408, "SPIKEVAX": 0.3172818216275339, "STELARA": 0.6466923704762555, "TOZINAMERAN": 0.6145518987729722, "TRUVADA": 0.1196786631049392, "VAXZEVRIA": 0.3144409596045958, "XELJANZ": 0.9408928597305722, "XOLAIR": 1.0835223494622606, "ZOSTAVAX": 0.9128714532197852, "null": 3.089311673091606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1154.json
index d843e2a326b..d63075a6b70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1154.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 15.298033765541591, "AUBAGIO": 2.159968391679767, "KEYTRUDA": 11.616221908715366, "LEMTRADA": 82.58039876066874, "OPDIVO": 10.746159253462151, "PEGASYS": 4.843458456607736, "PEGINTRON": 2.865633780662524, "PROPRANOLOL": 23.36938272372601, "SUTENT": 2.0195331748934207, "YERVOY": 15.645556184679588, "null": 1.2181815617617988}
\ No newline at end of file
+{"COMIRNATY": 0.9714333639742332, "GARDASIL": 15.68810972734583, "null": 0.1786799793800132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11540.json
new file mode 100644
index 00000000000..f24a4b3d12c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11540.json
@@ -0,0 +1 @@
+{"null": 1.4853375145356105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11541.json
new file mode 100644
index 00000000000..4060733457d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11541.json
@@ -0,0 +1 @@
+{"ABATACEPT": 2.9922363766505007, "ADALIMUMAB": 4.048494561145761, "ARAVA": 7.702402313809332, "AZATHIOPRINE": 11.594534990739502, "CIMZIA": 1.6627124500997534, "COMIRNATY": 0.7980722549377177, "COSENTYX": 14.284530705870417, "ENBREL": 3.6315275324338416, "ESOMEPRAZOLE": 9.149470188042338, "HUMIRA": 3.1616249765681133, "KEYTRUDA": 1.1230147865698017, "LEFLUNOMIDE": 24.482345810506185, "LEVOFLOXACIN": 4.435032802057571, "ROACTEMRA": 3.619049499191208, "SIMPONI": 1.6745408313947148, "SPIKEVAX": 0.2905890663166717, "TOZINAMERAN": 0.2185316480787336, "VAXZEVRIA": 0.2095391985795861, "null": 0.6426601917608228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11542.json
new file mode 100644
index 00000000000..18830cfe241
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11542.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3435064356621176, "null": 1.1881845312437305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11543.json
new file mode 100644
index 00000000000..b82065d5be4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11543.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.223020479483047, "AIMOVIG": 0.9140752908058416, "ARIPIPRAZOLE": 3.481111545580475, "AVANDIA": 1.2807736531195957, "BRINTELLIX": 8.625032770510163, "CHAMPIX": 2.9726039916013787, "CHORIOGONADOTROPIN": 213.8081397999383, "COMIRNATY": 0.6885310771896848, "CYMBALTA": 1.1551491093064088, "FOLLITROPIN": 123.06189481328347, "GARDASIL": 0.6129625315148833, "GONALF": 45.7047173502306, "KEPPRA": 1.5927142567127603, "OLANZAPINE": 2.923672521766745, "PLAVIX": 3.797044566747124, "SERTRALINE": 111.91417830769328, "SPIKEVAX": 0.4858639832147098, "TOZINAMERAN": 0.5260117640141435, "VAXZEVRIA": 0.5209884935548381, "ZYPREXA": 2.702980224401572, "null": 2.373107184472477}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11544.json
new file mode 100644
index 00000000000..29a046b4ae5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11544.json
@@ -0,0 +1 @@
+{"AIMOVIG": 5.216140410830566, "APIXABAN": 2.7383918961741798, "BRINTELLIX": 2.391071665599936, "BYDUREON": 4.678277425247648, "COMIRNATY": 1.6083965649810876, "CYMBALTA": 0.2553549553438863, "ELIQUIS": 0.2584589067924402, "GARDASIL": 2.118309119424083, "HYDROCORTISONE": 1.762493363262241, "KEPPRA": 0.3894253604756907, "OCRELIZUMAB": 6.2573695679210894, "SHINGRIX": 0.5446197379894043, "SPIKEVAX": 1.2330159487620242, "STELARA": 1.5502150393904832, "TOZINAMERAN": 3.8667162301681466, "VAXZEVRIA": 5.774973266970008, "ZOSTAVAX": 0.8434795804566396, "null": 0.3126711211238523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11545.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11545.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11546.json
new file mode 100644
index 00000000000..b304c76360e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11546.json
@@ -0,0 +1 @@
+{"KEPPRA": 35.01239797693851, "LEVETIRACETAM": 34.61988502289864, "null": 1.891551628954856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11547.json
new file mode 100644
index 00000000000..a9a3ccf07a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11547.json
@@ -0,0 +1 @@
+{"null": 1.456545919486572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11548.json
new file mode 100644
index 00000000000..4996b6f5059
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11548.json
@@ -0,0 +1 @@
+{"null": 2.7022563933339816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11549.json
new file mode 100644
index 00000000000..1ac8fbdcc29
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11549.json
@@ -0,0 +1 @@
+{"null": 0.3298069902451951}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1155.json
index 001d8ac5e9d..fba98c2d86e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1155.json
@@ -1 +1 @@
-{"AFINITOR": 1.9912786509671132, "ALEMTUZUMAB": 3.1351899913100523, "ARIPIPRAZOLE": 7.611731798884625, "AXITINIB": 11.253398831694664, "BAVENCIO": 18.57556911900037, "BEDAQUILINE": 8.214569741601311, "CABOMETYX": 11.051661152142914, "CAPRELSA": 18.479056598280355, "CLOPIDOGREL": 1.644480291252184, "DELAMANID": 7.788137702732822, "ERLEADA": 6.171918724559681, "EVEROLIMUS": 7.878227121765229, "INCIVO": 5.017106699976378, "INLYTA": 8.392077989410666, "INTRONA": 7.019218225295544, "KEYTRUDA": 13.781833974038578, "LEMTRADA": 21.87378383907581, "LENVIMA": 14.456303508549514, "METFORMIN": 22.850829720844008, "MULTAQ": 4.8979461643180615, "NEXAVAR": 2.807108039778952, "OPDIVO": 2.940238192872663, "PAZOPANIB": 12.126120596847892, "PEGASYS": 3.965919619290296, "PEGINTRON": 2.6907482269227407, "PEMBROLIZUMAB": 5.545284949608902, "PROPRANOLOL": 6.588234851312154, "STIVARGA": 5.465871739228595, "SUTENT": 14.966120304829834, "VOTRIENT": 8.970993236378499, "ZYPREXA": 1.4014942128631973}
\ No newline at end of file
+{"null": 0.7524205587329376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11550.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11550.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11551.json
new file mode 100644
index 00000000000..9dd24cbe6ee
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11551.json
@@ -0,0 +1 @@
+{"null": 6.400243216317942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11552.json
new file mode 100644
index 00000000000..aa10c83111c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11552.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 3.152119328421383, "COMIRNATY": 0.4225786526087452, "null": 0.4324287025053739}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11553.json
new file mode 100644
index 00000000000..2002a841843
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11553.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2975354822523058, "COSENTYX": 7.883606564674112, "SPIKEVAX": 0.3146341050906268, "TOZINAMERAN": 1.2523133704507765, "VAXZEVRIA": 0.4466775004839292, "null": 1.446748088831571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11554.json
new file mode 100644
index 00000000000..99b5bff159e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11554.json
@@ -0,0 +1 @@
+{"AFINITOR": 2.5927326126924237, "ANAKINRA": 75.131317669066, "ARANESP": 12.196159694664072, "COMIRNATY": 0.0282553975690641, "ENBREL": 2.538848227959197, "EXJADE": 8.640217524012392, "FAMPYRA": 6.324523773747727, "FASLODEX": 3.129734785968298, "IBRANCE": 2.163618043811311, "JAKAVI": 3.4810817178111835, "KEPPRA": 1.623725951003901, "KEYTRUDA": 1.739859460934275, "LONSURF": 8.481058799994022, "NEULASTA": 5.529934000448899, "OPSUMIT": 12.694353837942352, "REVATIO": 21.85705375953049, "SOLIRIS": 2.65513835926039, "STIVARGA": 3.174351485649747, "SUTENT": 0.5806285044198475, "TRACLEER": 15.756491734455532, "TRELEGY": 5.337816408434561, "VOTRIENT": 5.308851107708662, "XTANDI": 13.890725342976491, "null": 0.9862545735665686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11555.json
new file mode 100644
index 00000000000..c079965f928
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11555.json
@@ -0,0 +1 @@
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11556.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11556.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11557.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11557.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11558.json
new file mode 100644
index 00000000000..7efe7830168
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11558.json
@@ -0,0 +1 @@
+{"JARDIANCE": 98.20943844744632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11559.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11559.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1156.json
index 4a1e898f2da..d4f642e1714 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1156.json
@@ -1 +1 @@
-{"JANUMET": 13.024026602744229, "SUTENT": 3.5956512679216903, "ZOSTAVAX": 11.961908848001377}
\ No newline at end of file
+{"COMIRNATY": 0.4515840325903693, "IPILIMUMAB": 64.7715477480444, "KEYTRUDA": 37.8769781378934, "OPDIVO": 41.17946796875452, "null": 0.2604726543518937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11560.json
new file mode 100644
index 00000000000..7ec3f2f3c65
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11560.json
@@ -0,0 +1 @@
+{"BUSULFAN": 56.331684733474304, "TESTOSTERONE": 130.55584368399477, "null": 4.1867030266967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11561.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11561.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11562.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11562.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11563.json
new file mode 100644
index 00000000000..a1f70ae9a07
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11563.json
@@ -0,0 +1 @@
+{"null": 1.6950053364439617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11564.json
new file mode 100644
index 00000000000..6c1de9f8589
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11564.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.0989173765253809, "SUTENT": 2.0326820526824707, "VIAGRA": 66.94492655886829, "null": 2.3111700034972142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11565.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11565.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11566.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11566.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11567.json
new file mode 100644
index 00000000000..8b58fb9a4f1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11567.json
@@ -0,0 +1 @@
+{"null": 17.589420836847598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11568.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11568.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11569.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11569.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1157.json
index 6972e13596b..f64a8e52b42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1157.json
@@ -1 +1 @@
-{"ABACAVIR": 4.88779787963303, "ABILIFY": 2.604114978135373, "AFINITOR": 5.776707406822929, "ARIPIPRAZOLE": 2.5351018818900397, "ASPARAGINASE": 2.518795643407307, "ATAZANAVIR": 6.371910898749496, "AVANDIA": 2.735051850598865, "AZATHIOPRINE": 1.057598173495203, "BIKTARVY": 6.129767437266305, "BYDUREON": 3.946205933609871, "BYETTA": 7.668896028237928, "CICLOSPORIN": 1.0687347419978088, "CLOPIDOGREL": 1.1733351648183512, "COMBIVIR": 2.562798702562856, "COSENTYX": 1.3916027467003511, "CRIXIVAN": 15.357785872121385, "CYMBALTA": 1.577812318048643, "CYTARABINE": 1.107424035915897, "DARUNAVIR": 25.94930043054709, "DESCOVY": 9.10357511275836, "DULOXETINE": 1.5733293450137456, "EFAVIRENZ": 10.750570711305576, "EMTRICITABINE": 5.250018360232792, "ENTRESTO": 3.1193379666092924, "EPIVIR": 7.853861671449067, "ERLEADA": 2.954688166576865, "EVEROLIMUS": 7.099972640559061, "EVISTA": 2.623569961709125, "EXFORGE": 2.9673874075255724, "FORXIGA": 3.4707863201197453, "GALVUS": 5.639325784012208, "GENVOYA": 7.239790169897224, "INCIVO": 1.5107755261222249, "INSULIN": 1.4374247172731294, "INVIRASE": 23.748769832251284, "JAKAVI": 1.6885306800007456, "JANUMET": 3.774069154477545, "JANUVIA": 2.253327068895556, "JARDIANCE": 1.2313814523794724, "KALETRA": 12.050641833005118, "LAMIVUDINE": 2.870412780134394, "LATUDA": 2.547497133082527, "LYRICA": 1.0657368892467285, "NORVIR": 3.241793039219291, "OLANZAPINE": 4.521105132450023, "OZEMPIC": 18.80834962081988, "PANTOPRAZOLE": 3.869062506021319, "PEGASYS": 2.433619121002644, "PEGINTRON": 1.678930123610531, "RAPAMUNE": 4.762726277158749, "REMDESIVIR": 9.456787126350733, "REYATAZ": 4.994795360898335, "RINVOQ": 6.250642925383463, "ROACTEMRA": 3.868470873712615, "SOLIRIS": 1.2007746672458992, "STELARA": 1.859193757294721, "SUTENT": 1.6590027832468264, "TORISEL": 13.50879310967688, "TREMFYA": 1.6093208076086754, "TRULICITY": 5.552568769330999, "VIAGRA": 1.3095448687193596, "VICTOZA": 2.7627493888279755, "XELJANZ": 1.6591856877440907, "ZYPREXA": 33.84626014211938, "null": 1.133975017365548}
\ No newline at end of file
+{"COMIRNATY": 1.016372992115326, "LEMTRADA": 128.63954253890964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11570.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11570.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11571.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11571.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11572.json
new file mode 100644
index 00000000000..30380b6ee3a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11572.json
@@ -0,0 +1 @@
+{"null": 1.719128601799418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11573.json
new file mode 100644
index 00000000000..40c6742b0b8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11573.json
@@ -0,0 +1 @@
+{"null": 1.694721013906438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11574.json
new file mode 100644
index 00000000000..41651713749
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11574.json
@@ -0,0 +1 @@
+{"null": 0.9124907343506812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11575.json
new file mode 100644
index 00000000000..17f2ab177a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11575.json
@@ -0,0 +1 @@
+{"null": 1.1639063761139952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11576.json
new file mode 100644
index 00000000000..e04500741ed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11576.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 181.403858989946}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11577.json
new file mode 100644
index 00000000000..9d93b234fc4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11577.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 2.8914284553867344, "COMIRNATY": 0.5788372579756661, "JARDIANCE": 1.6178426432901338, "KAFTRIO": 22.404519829163736, "PEGASYS": 1.0801670237470595, "SPIKEVAX": 1.3066328848770894, "SUTENT": 0.6858050669347142, "TOZINAMERAN": 1.4304162331389934, "UROREC": 47.36730823918848, "VAXZEVRIA": 0.8234771416663617, "VIAGRA": 7.936793095010385, "XTANDI": 1.6560571672179072, "null": 2.1194133720922226}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11578.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11578.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11579.json
new file mode 100644
index 00000000000..3567e569364
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11579.json
@@ -0,0 +1 @@
+{"null": 1.1414720922686423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1158.json
index 03b778baaf1..a0104ca4618 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1158.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"AIMOVIG": 2.424039290225444, "ALEMTUZUMAB": 15.135092829012525, "BETAFERON": 6.594795665515045, "BYETTA": 6.35488335425773, "COMIRNATY": 1.3968467577332675, "COSENTYX": 0.8145359210144287, "GARDASIL": 6.604799007513588, "HUMALOG": 0.594681461515393, "IPILIMUMAB": 24.84058458649042, "KALETRA": 5.556058294561598, "KEYTRUDA": 7.639380350609758, "LEMTRADA": 53.81539885501928, "OPDIVO": 10.513798600314455, "PEGASYS": 4.758853497458105, "PEGINTERFERON": 9.667195420543443, "PEGINTRON": 5.786724383722938, "PEMBROLIZUMAB": 11.735728824410394, "SAXENDA": 2.2262395950530425, "SOMATROPIN": 14.285540665721554, "SPIKEVAX": 0.5593556859217846, "STELARA": 1.1709150392741774, "SUTENT": 0.9193885958704549, "TASIGNA": 2.619906398452732, "TOZINAMERAN": 0.822109443966057, "TREMFYA": 3.5122315450733192, "TWINRIX": 10.214820989657216, "VAXZEVRIA": 0.225145071455184, "XOLAIR": 1.270746637491642, "null": 0.486889177092418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11580.json
new file mode 100644
index 00000000000..0652ad23af8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11580.json
@@ -0,0 +1 @@
+{"VIAGRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11581.json
new file mode 100644
index 00000000000..3982c4303f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11581.json
@@ -0,0 +1 @@
+{"null": 0.6842411932383017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11582.json
new file mode 100644
index 00000000000..1703bc07046
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11582.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 9.788145474410518, "COMIRNATY": 0.4436434681540497, "PEGASYS": 3.4487037979944333, "SPIKEVAX": 0.6869713123126467, "SUTENT": 2.178683498105063, "TOZINAMERAN": 1.0837944335709735, "VAXZEVRIA": 0.3920786800292142, "VIAGRA": 25.60408404796653, "null": 1.0129642637667615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11583.json
new file mode 100644
index 00000000000..7b3aa3a9d26
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11583.json
@@ -0,0 +1 @@
+{"null": 1.4308638089904002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11584.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11584.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11585.json
new file mode 100644
index 00000000000..370b00dd0a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11585.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1034191556775362, "SIMPONI": 2.2837632330912627, "STELARA": 3.332737979450381, "SUBOXONE": 3.000535786984568, "null": 8.975529933652505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11586.json
new file mode 100644
index 00000000000..bf7cf95d918
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11586.json
@@ -0,0 +1 @@
+{"null": 1.820352752819057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11587.json
new file mode 100644
index 00000000000..06fb866fd67
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11587.json
@@ -0,0 +1 @@
+{"null": 0.8249481424895455}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11588.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11588.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11589.json
new file mode 100644
index 00000000000..24195fd1985
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11589.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8323849108203772, "DEXAMETHASONE": 4.402570216952578, "GARDASIL": 4.741035066336757, "MIMPARA": 45.6760341801204, "SPIKEVAX": 0.4376214716560971, "VAXZEVRIA": 0.4380287341947591, "null": 2.036640109449777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1159.json
index 3a8c764fddd..3961908b01d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1159.json
@@ -1 +1 @@
-{"SOLIRIS": 11.157115973904633, "null": 1.2945354392466195}
\ No newline at end of file
+{"ILARIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11590.json
new file mode 100644
index 00000000000..ab1eec45b87
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11590.json
@@ -0,0 +1 @@
+{"null": 3.4749924665981826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11591.json
new file mode 100644
index 00000000000..e988bce348b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11591.json
@@ -0,0 +1 @@
+{"KEPPRA": 12.17768028469398, "SUBOXONE": 22.256054113152867, "null": 2.50538968830264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11592.json
new file mode 100644
index 00000000000..3d8c3ba5906
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11592.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.0470889227841376, "ELIQUIS": 3.594338951666211, "SPIKEVAX": 0.8361989202056531, "VAXZEVRIA": 0.949772577906911, "null": 0.3796142084112076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11593.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11593.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11594.json
new file mode 100644
index 00000000000..82e0fd150dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11594.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 9.861546505244773, "COMIRNATY": 0.4217782784567125, "ELIQUIS": 53.64453445354853, "EVENITY": 16.490124475169907, "LIXIANA": 44.3668783129533, "PEGASYS": 1.4807259901308445, "PEGINTRON": 7.532296595928472, "PLAVIX": 11.219754066794302, "VAXZEVRIA": 0.1301540680917776, "XARELTO": 12.366845981219775, "null": 0.6226584527077234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11595.json
new file mode 100644
index 00000000000..8f2ee5aefa6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11595.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 71.03986037438747, "null": 0.5433282862058165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11596.json
new file mode 100644
index 00000000000..b79c531e6b8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11596.json
@@ -0,0 +1 @@
+{"HUMIRA": 198.03109718244352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11597.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11597.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11598.json
new file mode 100644
index 00000000000..51e55585887
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11598.json
@@ -0,0 +1 @@
+{"SUBOXONE": 26.88118075796904, "null": 2.330817813343336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11599.json
new file mode 100644
index 00000000000..7380909753a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11599.json
@@ -0,0 +1 @@
+{"null": 2.907983926807008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/116.json
index 3f5f368e6ba..c2a3fe65eb6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/116.json
@@ -1 +1 @@
-{"ACLIDINIUM": 9.794300711062869, "ARANESP": 97.07337389774403, "ASPARAGINASE": 3.2819947731632566, "CLOPIDOGREL": 3.4532026165654037, "CYTARABINE": 3.438429960056684, "ELIQUIS": 3.0162374261426783, "ENOXAPARIN": 15.26265350376409, "ENTRESTO": 2.617762956053923, "EXJADE": 3.5273290095828997, "HEMLIBRA": 72.05148900873449, "KYMRIAH": 11.55304010966129, "LIXIANA": 4.705462149717445, "PLAVIX": 2.432589292809432, "PRADAXA": 24.961551686533923, "PRAXBIND": 38.83887178682311, "SPINRAZA": 5.483916253970602, "XARELTO": 12.21657314395192, "null": 1.4863132049277188}
\ No newline at end of file
+{"ABASAGLAR": 181.5460973674148, "COSENTYX": 2.3273615147069857, "FORSTEO": 6.462448160298963, "HUMALOG": 57.48357870315213, "INSULIN": 19.67120922741212, "MOVYMIA": 331.37723142486703, "PLEGRIDY": 26.658821280480822, "ROTATEQ": 48.418433487119, "RUBRACA": 15.58824161343866, "SIMPONI": 3.559825703419031, "SPIKEVAX": 0.1390249079459189, "TRULICITY": 43.03843712659554, "null": 0.6323859767191506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1160.json
index 1214a6f3ed9..6fea444c62c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1160.json
@@ -1 +1 @@
-{"CELECOXIB": 21.961234813844317, "EMEND": 52.37347235055133, "ESOMEPRAZOLE": 37.75534749967666, "EXJADE": 5.791122947023763, "GARDASIL": 2.9716137295692797, "OLANZAPINE": 13.90761467769775, "PEGASYS": 1.5585955443068484, "null": 1.1260227274153218}
\ No newline at end of file
+{"ANAKINRA": 235.28520281894848, "COMIRNATY": 0.7628806989257979, "CYMBALTA": 10.511355711435918, "METHOTREXATE": 29.15409874430446, "null": 0.1379416932160287}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11600.json
new file mode 100644
index 00000000000..80f1cf40e5b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11600.json
@@ -0,0 +1 @@
+{"null": 1.0221374561695828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11601.json
new file mode 100644
index 00000000000..64674c2c6c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11601.json
@@ -0,0 +1 @@
+{"DIURETICS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11602.json
new file mode 100644
index 00000000000..62ef022143c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11602.json
@@ -0,0 +1 @@
+{"null": 2.2991170056727546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11603.json
new file mode 100644
index 00000000000..17f0dd6641a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11603.json
@@ -0,0 +1 @@
+{"ABATACEPT": 13.2840236306881, "ACTRAPID": 1.6132510063689818, "ADALIMUMAB": 5.862857282642785, "ADVATE": 2.1669892705539557, "AERIUS": 1.5056893907105953, "AIMOVIG": 4.364358634203685, "AMINOSALICYLIC": 0.610671415216887, "ANAKINRA": 16.05353190394737, "APIDRA": 0.4759274184984172, "APREMILAST": 10.591935002520287, "ARANESP": 1.3866457791858682, "ARAVA": 11.316867756933028, "ARIPIPRAZOLE": 0.2703288763094605, "ATRIPLA": 0.0545781817158866, "AUBAGIO": 0.2165285790470744, "AZATHIOPRINE": 10.120561489029209, "BARACLUDE": 1.3235500307445145, "BENLYSTA": 0.8388461989800761, "BETMIGA": 1.125855778301093, "BLINCYTO": 4.227545948602611, "BRIDION": 1.3151684293768182, "BRINTELLIX": 0.6692793662224896, "BUDESONIDE": 0.8705362301328453, "BUPRENORPHINE": 0.7609184301444237, "CERTOLIZUMAB": 9.091449399098853, "CHLORHEXIDINE": 40.964734001387, "CIALIS": 1.714630657059249, "CICLOSPORIN": 0.9047476445902728, "CIMZIA": 19.037697971868138, "CINRYZE": 3.2720390997967184, "CLOPIDOGREL": 0.2056649299680135, "COMIRNATY": 0.0161300077759981, "CORTICOSTEROIDS": 6.573842814511015, "COSENTYX": 4.675367917473597, "CYMBALTA": 0.6982959833749901, "CYTARABINE": 0.1957804333610378, "DAXAS": 13.85321575408534, "DEXAMETHASONE": 0.2693751461109184, "ELIQUIS": 0.1054711526515663, "ENBREL": 18.31930353388568, "ENTYVIO": 1.9099342590067716, "ERELZI": 14.526241650555152, "ERENUMAB": 2.475058937947217, "ETANERCEPT": 4.679466883949853, "EXFORGE": 0.3550986521782237, "EYLEA": 1.0049121052973695, "FAMPYRA": 5.3262657007521, "FASENRA": 2.2366400483414783, "FENTANYL": 0.5948786920692962, "FIASP": 10.71812821943636, "FIRDAPSE": 1.9093550513454485, "FYCOMPA": 1.5503988295431963, "GLYCOPYRRONIUM": 1.9361027806287177, "GOLIMUMAB": 6.12036585884248, "HUMALOG": 0.5511687655599354, "HUMIRA": 12.403050313452557, "IBUPROFEN": 0.5196610457533228, "INSULIN": 0.2840886877468909, "INVEGA": 2.461156267610725, "JANUVIA": 0.3237557069332706, "KEPPRA": 0.7757460730192631, "KEYTRUDA": 0.1183941755753461, "LACOSAMIDE": 1.3983096975589833, "LANTUS": 0.4280356016993564, "LEFLUNOMIDE": 2.0385937466456334, "LEVEMIR": 0.8936126974153008, "LEVETIRACETAM": 0.8908446758480071, "LEVOFLOXACIN": 0.1451204933475304, "LYRICA": 0.2903652145726328, "MEPOLIZUMAB": 1.7981745517786565, "METHOTREXATE": 1.6726003826564917, "MICARDIS": 0.6502148496893269, "MIMPARA": 1.0914222161531657, "MIRCERA": 1.555728703464133, "NEULASTA": 1.0179681932103417, "NOT": 0.7053591885756932, "NOVORAPID": 3.4504728421063526, "NPLATE": 6.578052971960744, "NUCALA": 0.8908433906314647, "OLANZAPINE": 0.6160131873833201, "OMALIZUMAB": 0.4326499259448073, "PEGASYS": 0.1093649496332828, "PLAVIX": 0.119077699932, "QUTENZA": 3.226998852160731, "REMICADE": 2.918867482077456, "RINVOQ": 4.595543285937847, "RITUXIMAB": 1.178578325294232, "ROACTEMRA": 1.2957610880756651, "SAXENDA": 1.5611628713407129, "SIFROL": 3.0787677808053973, "SILDENAFIL": 1.288827568494375, "SIMPONI": 3.998414089879866, "SKYRIZI": 3.2939890061616617, "SOLIRIS": 0.4088301932489488, "SPIKEVAX": 0.0133077520054567, "SPINRAZA": 2.681196153624524, "STALEVO": 2.360618906236981, "STELARA": 4.232244166568535, "TESTOSTERONE": 2.214050043694165, "TOUJEO": 0.96221644298978, "TOVIAZ": 1.8820052201154496, "TREMFYA": 2.917886861294342, "TRESIBA": 2.215382855872344, "UPADACITINIB": 4.62823904907316, "VAXZEVRIA": 0.0065831616585463, "VIAGRA": 2.099528820459497, "XELJANZ": 1.4004324074653796, "XOLAIR": 0.5246560280433749, "XTANDI": 0.165450654830609, "ZYPREXA": 0.2660708482239179, "null": 0.6968058803610838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11604.json
new file mode 100644
index 00000000000..d802ee50e7f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11604.json
@@ -0,0 +1 @@
+{"AIMOVIG": 2.624268920180362, "APIDRA": 6.612883497172784, "ARAVA": 0.384545546622927, "BRIDION": 17.856635715926203, "COMTAN": 17.956448450638707, "COSENTYX": 2.424430818196534, "ENTYVIO": 7.088025723293512, "FIASP": 150.43406455873426, "HUMALOG": 6.786183886353623, "LANTUS": 0.9667620666955874, "NOVORAPID": 27.38947306592321, "VIAGRA": 17.983703138134878, "XELJANZ": 12.893422845406205, "null": 1.9024542300121832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11605.json
new file mode 100644
index 00000000000..39c5691c426
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11605.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.9412091490124624, "ABILIFY": 6.058721021609807, "ACLIDINIUM": 11.954819182696554, "ADALIMUMAB": 3.4473623278116103, "AERIUS": 1.209490309533097, "AFINITOR": 0.2448591853221581, "AIMOVIG": 2.972423450439662, "ALENDRONATE": 18.54327645777149, "AMGEVITA": 14.748424972215682, "AMINOSALICYLIC": 12.73320183819205, "ANAKINRA": 10.098439308614196, "ANORO": 3.78525791044472, "APIXABAN": 11.18146364286868, "ARANESP": 0.5140385397823745, "ARAVA": 3.110579486270014, "ARIPIPRAZOLE": 9.359132258917452, "AVAMYS": 28.04839728663804, "AVASTIN": 0.2561046621709703, "AXITINIB": 0.7225763381531533, "AZACITIDINE": 3.207622870808815, "AZATHIOPRINE": 5.232780578767459, "AZOPT": 17.83718082994475, "BENLYSTA": 1.314381847965204, "BENRALIZUMAB": 33.81704893569509, "BETMIGA": 2.971112277528776, "BEVACIZUMAB": 1.942736627918175, "BORTEZOMIB": 5.205485490624876, "BOTULINUM": 3.909445526748856, "BRIDION": 2.119096417483677, "BRINTELLIX": 0.3556513578327792, "BRIVARACETAM": 2.8306722230930075, "BRIVIACT": 1.7939299816699483, "BUDESONIDE": 14.466641687330805, "BUPIVACAINE": 0.8052471480384582, "BUPRENORPHINE": 0.6119233591779148, "BYDUREON": 0.2078284967772078, "C1": 6.700239562680315, "CABOMETYX": 0.2450430950788255, "CAELYX": 1.256141410376275, "CAPECITABINE": 0.9978604520993845, "CARBIDOPA": 1.3071090224625448, "CARFILZOMIB": 3.1316525731392773, "CARMUSTINE": 0.8801204583136891, "CASPOFUNGIN": 1.6856442237138518, "CERTOLIZUMAB": 5.90620767203617, "CHAMPIX": 0.1438095598417777, "CICLOSPORIN": 1.883686993171744, "CIMZIA": 1.9393744927050152, "CLADRIBINE": 3.4416138160063747, "CLOPIDOGREL": 0.3216102428260237, "COMIRNATY": 0.0030089168218769, "COSENTYX": 5.3307788851486695, "CYMBALTA": 0.441733272297416, "CYTARABINE": 1.9281897005650763, "DARZALEX": 1.292830920474492, "DASATINIB": 1.122664813428154, "DAXAS": 16.78249805602869, "DESLORATADINE": 8.12869851958033, "DEXAMETHASONE": 1.2751086894505437, "DEXMEDETOMIDINE": 2.33233540626082, "DOCETAXEL": 0.7701139817107513, 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"METHOTREXATE": 3.005542210933668, "MICARDIS": 0.389659052458397, "MIDAZOLAM": 1.965425757468739, "MIMPARA": 2.550045975516255, "MYCOPHENOLATE": 0.4999387766469189, "NEULASTA": 0.95772826819451, "NEXAVAR": 0.182252139816747, "NOT": 0.5678789792350973, "NOVORAPID": 0.6491667198195593, "NOVOSEVEN": 0.8912988685033588, "NPLATE": 1.1586260967463076, "NUCALA": 24.439801827157947, "OFEV": 0.2155580583692651, "OLANZAPINE": 1.1999519488104105, "OMALIZUMAB": 2.427804415140953, "OPSUMIT": 0.535179037770399, "PACLITAXEL": 0.6240168647163918, "PANITUMUMAB": 2.1212230937447853, "PANTOPRAZOLE": 3.3180012521308546, "PEGINTERFERON": 0.4887543830725737, "PEGINTRON": 0.1506770694786403, "PEMBROLIZUMAB": 0.959524740361573, "PEMETREXED": 1.3903477745305144, "PREGABALIN": 6.293499168267745, "PRIVIGEN": 0.641893343795468, "QUTENZA": 2.425639602122521, "RELVAR": 1.7709522529603852, "REMICADE": 2.1204925997415667, "REVATIO": 1.0007669015553744, "REVOLADE": 5.53348925887042, "RINVOQ": 4.322893890497591, "RIOCIGUAT": 20.75869366568164, "RITUXIMAB": 1.033954984149811, "RUCONEST": 12.941331693397478, "SILDENAFIL": 1.010918823872344, "SIMPONI": 0.735567867407347, "SKYRIZI": 2.7337508623495435, "SOLIRIS": 0.5693793425268433, "SPIRONOLACTONE": 0.8738380347723947, "STELARA": 1.1307347223759858, "SUBOXONE": 0.5114682944293696, "TASIGNA": 0.1502634428390103, "TELMISARTAN": 5.949670181101318, "TEMOZOLOMIDE": 2.276155543131332, "TOVIAZ": 5.724249445277831, "TRELEGY": 2.8688196349305906, "TREMFYA": 1.0235198206227023, "UMECLIDINIUM": 25.302489716408, "UPADACITINIB": 2.655454623094807, "VARENICLINE": 7.740702146711989, "VECTIBIX": 1.293818032671153, "VENETOCLAX": 1.5813178095168243, "VFEND": 0.5438042083825262, "VIAGRA": 3.866545059249072, "VIGABATRIN": 2.921944205234387, "VIMPAT": 0.5833766884736807, "VORICONAZOLE": 1.7440342572725158, "XELJANZ": 10.41645584293121, "XOLAIR": 0.7638206901068172, "XTANDI": 0.2411571411170573, "ZOSTAVAX": 0.1255804165634078, "null": 0.7065114703448073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11606.json
new file mode 100644
index 00000000000..6e8e6747d53
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11606.json
@@ -0,0 +1 @@
+{"FENTANYL": 3.1677416803901792, "HUMALOG": 2.3377873567004523, "IBUPROFEN": 4.964264467448023, "LANTUS": 1.555264639317211, "null": 3.839091970179245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11607.json
new file mode 100644
index 00000000000..0a8c48d20c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11607.json
@@ -0,0 +1 @@
+{"VIAGRA": 23.9103810965175, "null": 4.390093823480931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11608.json
new file mode 100644
index 00000000000..97295260a84
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11608.json
@@ -0,0 +1 @@
+{"ABILIFY": 163.73466877154402, "ARIPIPRAZOLE": 274.1921525867308, "CICLOSPORIN": 4.023964930005548, "FIASP": 53.105618289336135, "NOVORAPID": 7.983874734806173, "XELJANZ": 1.604188769403191, "null": 0.434000692299882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11609.json
new file mode 100644
index 00000000000..72199ad1f9b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11609.json
@@ -0,0 +1 @@
+{"null": 1.5033643846546798}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1161.json
index 02d256eb8f3..c05cebe08f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1161.json
@@ -1 +1 @@
-{"ACTOS": 2.704378260067727, "AFINITOR": 1.860737508960563, "ALIMTA": 1.2118839614421908, "AMINOSALICYLIC": 1.246751560923281, "ANAKINRA": 1.4815266652700894, "APROVEL": 2.3483416919651763, "ARIPIPRAZOLE": 2.6548767652603, "ASPARAGINASE": 1.4235671972191215, "BARACLUDE": 6.882917689052484, "BEDAQUILINE": 1.7837782474744777, "BEVACIZUMAB": 1.1534013581922276, "BRILIQUE": 1.4202599757054033, "BUMETANIDE": 3.896770444755978, "BUSULFAN": 1.3337461641045307, "BYETTA": 1.3848343324166144, "CELECOXIB": 14.459985007011982, "CELLCEPT": 1.8668992700982012, "CICLOSPORIN": 3.679900669010012, "CLOPIDOGREL": 1.843292450801804, "COAPROVEL": 2.79195058802337, "COMBIVIR": 1.5546983503808962, "CRIXIVAN": 9.30572159573579, "CUBICIN": 1.9830073024781367, "DELAMANID": 3.247060573801644, "DELTYBA": 26.34738675984425, "DENOSUMAB": 4.096522747734538, "EMEND": 2.7560912039608323, "ENTRESTO": 9.26840210392079, "EPIVIR": 1.6739200346871013, "EVEROLIMUS": 4.669591411647087, "EXFORGE": 3.770019833945181, "EXJADE": 15.412722482895717, "FEBUXOSTAT": 3.647447341047908, "FORXIGA": 3.329751403912263, "GALVUS": 3.420815113803165, "GLIVEC": 2.895534618079424, "HYCAMTIN": 5.375157798213568, "IBUPROFEN": 3.1792103723705267, "INLYTA": 1.5977658832035693, "IRBESARTAN": 1.3669238590550397, "ISOPHANE": 27.438388995160302, "JAKAVI": 1.3088035189920255, "LEVOFLOXACIN": 1.8929786494013048, "MICARDIS": 7.788732948248307, "MULTAQ": 3.67620570405038, "MYCOPHENOLATE": 1.2673170310511686, "OLANZAPINE": 1.3306266154005046, "OPSUMIT": 1.2384848202317889, "PANTOPRAZOLE": 3.181715967550581, "PEGINTERFERON": 2.052053170207212, "RASILEZ": 18.10853668605657, "REMDESIVIR": 4.529319273436117, "RIVAROXABAN": 8.15278520847671, "RUBRACA": 1.5164969818235234, "SAMSCA": 16.712761217307744, "SOLIRIS": 3.470609917540145, "SPIRONOLACTONE": 7.348090767427529, "SUTENT": 2.212229675120896, "TELMISARTAN": 3.140265540239677, "TENOFOVIR": 8.805888805590932, "TOBRAMYCIN": 11.694635508630489, "TORISEL": 4.145565248902495, "VALSARTAN": 6.219175477943817, "VFEND": 1.140541804061436, "VIREAD": 2.15818720768301, "ZOMETA": 10.988333564731985, "ZONISAMIDE": 10.683918867731062, "null": 2.4067656008320184}
\ No newline at end of file
+{"null": 1.896811610363225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11610.json
new file mode 100644
index 00000000000..18ee9fc9362
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11610.json
@@ -0,0 +1 @@
+{"AERIUS": 12.994288512854354, "CIMZIA": 1.428797578073711, "COSENTYX": 1.5411063946900352, "ENBREL": 3.2313901950431805, "EYLEA": 4.799613353660498, "KEPPRA": 5.115851224268841, "LANTUS": 2.1525287536454183, "NOXAFIL": 44.95315197238797, "OLANZAPINE": 1.953358140659173, "PEGASYS": 4.127230288387025, "PEGINTRON": 7.002435721320284, "RASAGILINE": 305.2553639664196, "SIMPONI": 4.6929580207452375, "SPIKEVAX": 0.0822044056659841, "STELARA": 4.155370818920168, "STIVARGA": 3.411395627791608, "SUBOXONE": 18.0947818536596, "VAXZEVRIA": 0.2071612635831976, "VIMPAT": 11.11257082977158, "null": 1.1377868925073802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11611.json
new file mode 100644
index 00000000000..65135efc185
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11611.json
@@ -0,0 +1 @@
+{"BRIVARACETAM": 625.9010999964784, "null": 2.299933554056661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11612.json
new file mode 100644
index 00000000000..6826379b8b2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11612.json
@@ -0,0 +1 @@
+{"ENTYVIO": 2992.497252053788, "null": 0.1134416501065868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11613.json
new file mode 100644
index 00000000000..909a81e8591
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11613.json
@@ -0,0 +1 @@
+{"LEVETIRACETAM": 10.204610223234935, "null": 3.691927166616814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11614.json
new file mode 100644
index 00000000000..3b4e6fa7d5e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11614.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.5769977963382406, "ABILIFY": 0.8358653374142707, "ACLIDINIUM": 1.3665837301103836, "ADALIMUMAB": 1.3797963060416705, "AFINITOR": 1.2272293098834024, "AIMOVIG": 3.885546587307346, "ALEMTUZUMAB": 2.0785364773907613, "ANAKINRA": 1.7136637720482644, "APIDRA": 2.5784233596194137, "ARANESP": 18.613193168478396, "ARAVA": 1.408650777172521, "ARIPIPRAZOLE": 2.734893341967085, "ASPARAGINASE": 0.5185157369789709, "ATRIPLA": 0.0261434509475979, "AUBAGIO": 1.6325728167373537, "AVASTIN": 1.087116451199002, "AZATHIOPRINE": 1.2753528363916296, "BARACLUDE": 9.067227968088512, "BASILIXIMAB": 3.120586472987656, "BENLYSTA": 0.8556975905742489, "BEVACIZUMAB": 1.869465910525228, "BORTEZOMIB": 4.563276934575213, "BOSULIF": 1.0444345582013843, "BOSUTINIB": 6.412247663861899, "BOTULINUM": 2.97968779389072, "BRIDION": 0.9312260600203528, "BRINTELLIX": 0.5153851774449009, "BUDESONIDE": 0.9953565423860572, "BUPIVACAINE": 9.22917049411167, "BUPRENORPHINE": 1.2559278927686215, "BUSULFAN": 0.5605411812753294, "CAPECITABINE": 1.6840148645755335, "CASPOFUNGIN": 1.7440925304205366, "CELLCEPT": 1.144251215392149, "CICLOSPORIN": 3.994162786755046, "CIMZIA": 1.9274071696072528, "CLOPIDOGREL": 0.5002383628396907, "COMIRNATY": 0.0041884760707841, "COSENTYX": 2.2244423532937376, "CYMBALTA": 1.4393383024123012, "CYTARABINE": 2.071291989921132, "DABRAFENIB": 6.037042566921579, "DAPAGLIFLOZIN": 3.1790997495259634, "DARZALEX": 1.917293531002567, "DASATINIB": 11.392688160475322, "DENOSUMAB": 2.5901418770560047, "DEXAMETHASONE": 2.301246067621852, "DOCETAXEL": 1.1148728012920297, "DULOXETINE": 0.6684133569140678, "DUPIXENT": 3.349835825989292, "EFAVIRENZ": 1.1061587429029078, "ELIQUIS": 0.5643978098919754, "EMTRICITABINE": 1.3063934804203674, "ENBREL": 5.320050389817578, "ENTECAVIR": 6.628839912534524, "ENTYVIO": 1.8110354715594168, "EPOETIN": 9.214228158083106, "ERLEADA": 1.4363493544317598, "ESOMEPRAZOLE": 1.1929712368564878, "EVEROLIMUS": 1.6195801323144077, "EVRA": 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1.531969777651448, "PROPRANOLOL": 3.0059664069691867, "RELVAR": 1.844078003151285, "REMICADE": 4.515607138305059, "REVLIMID": 1.2170014889561551, "RIBAVIRIN": 1.7776356728938976, "RIBOCICLIB": 2.8099632725825394, "RITUXIMAB": 1.7875325416184005, "RUXOLITINIB": 7.238686517410013, "SIMPONI": 5.762320150730029, "SOLIRIS": 1.729141779528668, "SPRYCEL": 4.487283938373748, "STELARA": 12.212703122672725, "SUBOXONE": 0.987518128930252, "TASIGNA": 2.204509276585839, "TELITHROMYCIN": 129.52114819956003, "TOUJEO": 4.557087721233061, "TOVIAZ": 4.108954361501141, "TRAMETINIB": 8.513841285544412, "TREMFYA": 6.794238734591018, "TWINRIX": 5.992508170172144, "UMECLIDINIUM": 5.095694980690195, "VEKLURY": 8.76199888577277, "VEMURAFENIB": 6.2988866555371175, "VFEND": 0.3805489436322719, "VIMPAT": 0.7471013050854426, "VIREAD": 1.0876069035569422, "VORICONAZOLE": 2.779059586604084, "VOTRIENT": 0.7942290726357165, "XELJANZ": 0.5331510544335324, "XOLAIR": 0.9293314056050588, "XYREM": 1.7465624636796564, "ZYPREXA": 0.2722246433791077, "null": 1.0060452530473172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11615.json
new file mode 100644
index 00000000000..c820a0178db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11615.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 10.897642711489317, "DAPTOMYCIN": 385.6011702657819, "FIRDAPSE": 85.94966454681091, "HUMALOG": 9.701570799173686, "PEGASYS": 2.0026783142203635, "null": 1.076402113144722}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11616.json
new file mode 100644
index 00000000000..c70d57e1f21
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11616.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 3.7658104307419937, "KEYTRUDA": 2.2962881443385816, "null": 9.805590631041907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11617.json
new file mode 100644
index 00000000000..9415b4526d9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11617.json
@@ -0,0 +1 @@
+{"null": 5.022599580997733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11618.json
new file mode 100644
index 00000000000..8f304c08d8c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11618.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.6697378625088038, "AIMOVIG": 20.63136005756477, "ARAVA": 0.8556372106363913, "BENLYSTA": 3.0257997701899004, "BUDESONIDE": 2.1395004511447726, "CARBIDOPA": 52.07944485007366, "CIMZIA": 13.941919370930329, "COMIRNATY": 0.043602970387743, "COMTAN": 81.8669098850534, "COSENTYX": 21.36423355476603, "ENBREL": 3.2921505274903216, "ENTACAPONE": 174.86863291804755, "ENTYVIO": 2.567559095567556, "FAMPYRA": 10.480044130453251, "FASENRA": 12.33655852009904, "FENTANYL": 1.4096273987911547, "FIRDAPSE": 64.89857066725571, "HUMALOG": 0.9280747313884488, "HUMIRA": 17.25792024670772, "LEVODOPA": 176.43122478116686, "NUCALA": 1.9464596966037773, "OMALIZUMAB": 2.661885064679637, "RINVOQ": 4.075667005363176, "SIMPONI": 2.6618177746257925, "SKYRIZI": 64.98127031151897, "SOLIRIS": 4.097425052512239, "SPINRAZA": 12.41470003414732, "STALEVO": 38.01429181564257, "STELARA": 4.264014493443645, "XELJANZ": 3.0170947112068576, "XOLAIR": 1.455418448150905, "null": 0.367643739223726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11619.json
new file mode 100644
index 00000000000..df9366bc0d1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11619.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 27.087702835363736, "ABILIFY": 1.4988382011636616, "AERIUS": 1.4607755250461925, "AIMOVIG": 1.5418665480526828, "APIDRA": 0.3990668751187344, "ARAVA": 0.0424215743361835, "AUBAGIO": 0.6950347293537222, "AVAMYS": 1.5109976987005214, "AVANDIA": 0.3198652486330328, "BENLYSTA": 3.927393154954128, "BIKTARVY": 0.8703050833946562, "BRINTELLIX": 2.7738746172496165, "BRIVARACETAM": 12.308380398785625, "BRIVIACT": 2.543404012021999, "BUPRENORPHINE": 1.346452476495363, "BYDUREON": 0.4648993227167727, "BYETTA": 0.3480160291672856, "CHAMPIX": 2.291988596302023, "CIALIS": 5.395926926585034, "CICLOSPORIN": 0.5821825801650835, "CIMZIA": 0.2574827339720827, "CLOPIDOGREL": 0.9252487782140136, "COMIRNATY": 0.5016368526690053, "COSENTYX": 0.8110265924963349, "CYMBALTA": 0.5585138936596052, "DARZALEX": 1.523572420280345, "DESLORATADINE": 6.18754248686704, "DUORESP": 19.013576572718616, "ELIQUIS": 0.6118406004132466, "ENTRESTO": 0.9315079242983884, "EPIDYOLEX": 31.182571112175136, "ESOMEPRAZOLE": 1.4881093688862166, "EVRA": 2.855973301553378, "EYLEA": 0.5395564314494194, "FAMPYRA": 1.501773392670806, "FASENRA": 1.3555140298304358, "FASLODEX": 0.4281286092124169, "FENTANYL": 0.3659369116729719, "FORXIGA": 0.8119180944777572, "FULVESTRANT": 1.0022122057035034, "GREPID": 25.80951651850826, "HARVONI": 2.027770948388397, "HUMAN": 11.54869382384525, "HUMIRA": 0.3233976350027037, "HYDROCHLOROTHIAZIDE": 4.561638438198443, "IBRANCE": 1.1083301615973729, "IBUPROFEN": 0.5257711408834286, "INSULIN": 0.5518562373312828, "IRBESARTAN": 4.408580087441388, "JAKAVI": 1.96885886240282, "JANUMET": 0.3669577577519456, "JANUVIA": 0.6992934205979883, "JARDIANCE": 1.3311922200493884, "KALETRA": 4.643175424482435, "KEPPRA": 0.8517629962115105, "KEYTRUDA": 0.6646406778846361, "LANTUS": 0.3826499398961729, "LATUDA": 3.0705175838565784, "LEVETIRACETAM": 0.8041247355240966, "LIXIANA": 1.2754049453248215, "LOPINAVIR": 36.98027181065961, "LYRICA": 1.8215133369217504, "MEPOLIZUMAB": 1.2066187056342323, "METHOTREXATE": 0.3560798562201284, "NPLATE": 1.0512022962700804, "NUCALA": 1.7045327260436458, "OCEAN": 48.33567229941479, "OFEV": 0.8232559349761452, "OLANZAPINE": 0.8468312365962829, "OMALIZUMAB": 0.3627795389674746, "PEGINTRON": 0.2635142282099658, "PLAVIX": 0.4491879064134869, "REVATIO": 2.610983391234152, "RIBAVIRIN": 1.1372422472282286, "RINVOQ": 1.786075182320784, "SHINGRIX": 0.6946931266495159, "SILDENAFIL": 1.3689814119343573, "SIMPONI": 0.668920547105532, "SOLIRIS": 0.5846925016861257, "SOMATROPIN": 3.0383413805651585, "SPIKEVAX": 0.2404330138336314, "STELARA": 1.4712024072995773, "STIVARGA": 0.3834975983907439, "SUBOXONE": 5.337495060274434, "SUTENT": 0.2956206983041409, "TOUJEO": 1.5359834071733336, "TOVIAZ": 0.9655135353719592, "TOZINAMERAN": 0.4249613436967964, "TRELEGY": 1.168360479842257, "TREMFYA": 4.627451092286901, "VAXZEVRIA": 0.2801361776723559, "VFEND": 0.577633462323863, "VIAGRA": 4.223510357457662, "VIMPAT": 2.2983915736907807, "VOTRIENT": 0.4663199834685508, "XELJANZ": 4.032259106394067, "XOLAIR": 0.9596314788653384, "XTANDI": 0.3240804401382305, "XYREM": 13.325031925648712, "null": 2.395064260170123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1162.json
index d4ccf3c855d..cee469b7fcf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1162.json
@@ -1 +1 @@
-{"null": 1.5866082288418275}
\ No newline at end of file
+{"FENTANYL": 49.39685163989798, "null": 1.2685970754618725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11620.json
new file mode 100644
index 00000000000..b705bc01f74
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11620.json
@@ -0,0 +1 @@
+{"ABILIFY": 4.838594741499675, "ACLIDINIUM": 43.81347348211298, "ANORO": 3.9640556405171616, "ARIPIPRAZOLE": 1.3282561211330013, "AUBAGIO": 1.494139271501015, "BENLYSTA": 6.063781065209198, "BRILIQUE": 10.711967147722389, "BRINTELLIX": 14.98936002329755, "BUDESONIDE": 0.7045685579250736, "BYDUREON": 3.868957804445592, "CIMZIA": 2.527091598103696, "CLOPIDOGREL": 1.5096726072328417, "CYMBALTA": 0.3567314529141931, "FAMPRIDINE": 37.72586113632104, "FASLODEX": 1.4743495489780545, "FORXIGA": 5.330040607055018, "HARVONI": 5.07525202273341, "HIZENTRA": 9.45002391931258, "IRESSA": 4.548772475714912, "JANUVIA": 1.2865981356323306, "KEPPRA": 1.3092169803922071, "LATUDA": 33.821684600323465, "LEVETIRACETAM": 2.247097765317061, "LIXIANA": 3.9256694180937184, "MEPOLIZUMAB": 2.811456522562386, "NUCALA": 4.222861213798744, "OLANZAPINE": 1.4879069340387352, "OPSUMIT": 3.0208720136691154, "PANTOPRAZOLE": 4.829008171187868, "RELVAR": 15.065164637026536, "RIBAVIRIN": 3.754166716740325, "RINVOQ": 1.9349644032708089, "SIMPONI": 3.207950368446388, "STALEVO": 11.894260365424236, "STELARA": 1.6286916627724533, "TRELEGY": 11.31147836413404, "TREMFYA": 17.12852859954857, "null": 1.814478130980984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11621.json
new file mode 100644
index 00000000000..41e65f44ccf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11621.json
@@ -0,0 +1 @@
+{"ABILIFY": 3.111395532765401, "BRINTELLIX": 5.405866799562959, "CINRYZE": 677.5994164670113, "COMIRNATY": 0.0376297050682822, "HIZENTRA": 10.995644492319196, "KEPPRA": 2.4855141749049103, "MIDAZOLAM": 11.152246920962847, "OPSUMIT": 32.75895478101228, "TRACLEER": 3.9962170262754384, "null": 1.8438094744985871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11622.json
new file mode 100644
index 00000000000..9903afaabee
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11622.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.4777034544992922, "ACLIDINIUM": 34.8688141095107, "AUBAGIO": 1.3094114182844483, "AVAMYS": 2.3063966025923097, "BENLYSTA": 11.487210344146284, "BRAFTOVI": 2.5810145777291447, "BRINTELLIX": 1.416665498601877, "BRIVIACT": 31.92832533302308, "BUPRENORPHINE": 2.5789724697234253, "CIMZIA": 28.24904881919503, "COMIRNATY": 0.0120257662242986, "ELIQUIS": 0.8116537440247212, "EVENITY": 6.469732792247984, "FIRDAPSE": 7.525964569882879, "HIZENTRA": 20.118399943103604, "HUMAN": 3.2037059707587785, "IKERVIS": 52.68667732857445, "KEPPRA": 4.178666326512145, "LATUDA": 34.15821001601951, "LUPKYNIS": 60.49324747626236, "NUCALA": 11.78809867421868, "OCALIVA": 57.92968715427239, "OLANZAPINE": 0.9300586791984018, "OPSUMIT": 2.640289889914358, "PANTOPRAZOLE": 5.386869642245824, "PRIVIGEN": 4.820215539929466, "RELVAR": 9.032214630686475, "SUBOXONE": 14.148756790127305, "TERROSA": 62.73146371117658, "TRELEGY": 5.816034999439452, "TREMFYA": 4.060496267129303, "VIMPAT": 8.308937075724902, "null": 1.70383343603376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11623.json
new file mode 100644
index 00000000000..dfff9b6ab18
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11623.json
@@ -0,0 +1 @@
+{"SUBOXONE": 241.7446505356844, "null": 0.6967559409027245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11624.json
new file mode 100644
index 00000000000..ecd8a6d3ddf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11624.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.4683851282979103, "ABATACEPT": 1.1217993078210702, "ABILIFY": 2.291972037666685, "ACCOFIL": 33.21451693189232, "ACTOS": 1.9987624407737192, "ADALIMUMAB": 2.517343296395937, "ADCIRCA": 1.4697017067992968, "ADEMPAS": 3.9233843042512255, "AFINITOR": 0.4841898739810455, "AGOMELATINE": 17.173636220924504, "AIMOVIG": 1.567780803021104, "ALEMTUZUMAB": 0.8403900304992735, "ALIMTA": 0.4809048213011559, "AMGEVITA": 21.989814889580988, "AMIKACIN": 3.188390642190167, "ANAKINRA": 3.132154404317054, "APREPITANT": 1.5671099487296198, "APROVEL": 2.702710992373264, "ARANESP": 3.1102060668438773, "ARAVA": 2.251672470631204, "ARIPIPRAZOLE": 2.1009561839236155, "ATRIPLA": 0.0513933786301749, "AVASTIN": 0.9261689369945664, "AVONEX": 5.702831530211742, "AZACITIDINE": 2.1710539905432444, "AZATHIOPRINE": 1.8526411390505164, "BEVACIZUMAB": 3.0005516832835024, "BINOCRIT": 29.644334281742356, "BLINATUMOMAB": 5.974035475415775, "BORTEZOMIB": 10.52608279075717, "BOSENTAN": 5.790455114399161, 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9.76263549467276, "IPILIMUMAB": 0.9853548853246944, "IRINOTECAN": 1.2318236269133045, "JAKAVI": 3.950903210773504, "JETREA": 19.687993823726767, "KEPPRA": 1.2907535360842557, "KETOCONAZOLE": 12.924946882997167, "KEYTRUDA": 0.9651312074299386, "KIOVIG": 1.6551884264124326, "KUVAN": 8.787689447599705, "KYMRIAH": 5.525414209116877, "KYPROLIS": 2.27011183267614, "LACOSAMIDE": 3.944760654412697, "LANTUS": 0.0804308085685801, "LEVEMIR": 0.6614344830628467, "LEVETIRACETAM": 3.3712185177511294, "LEVOFLOXACIN": 0.2713616265126338, "LYRICA": 1.374643165155372, "MEKINIST": 1.370246512166541, "MELATONIN": 1.2918744747846989, "METHOTREXATE": 0.8122191435288468, "MICAFUNGIN": 9.20547464625073, "MICARDIS": 2.519448098232737, "MIDAZOLAM": 1.6112980429762709, "MIMPARA": 5.92677545313313, "MIRCERA": 4.787486157925463, "MMRVAXPRO": 0.2319587769348964, "MYCOPHENOLATE": 4.002477248628407, "NEULASTA": 4.491010902321075, "NILOTINIB": 7.511141308791527, "NITRIC": 40.35757021236692, "NIVESTIM": 16.09817836440411, "NOT": 1.5803831767674403, "NOVORAPID": 0.4209618763907772, "NOVOSEVEN": 2.622233337489081, "NOXAFIL": 1.5019931812037908, "NPLATE": 7.144683989776053, "OFEV": 0.7024780347397879, "OLANZAPINE": 2.1809495833594674, "OLYSIO": 2.742954068419378, "OMALIZUMAB": 1.35231522542313, "OPSUMIT": 6.252947058722966, "PANTOPRAZOLE": 0.7333008177300376, "PEGASYS": 3.509193875149839, "PEGINTERFERON": 7.351679453579079, "PEGINTRON": 1.605729762262791, "PEMBROLIZUMAB": 6.448236394734161, "PLAVIX": 0.3261143845657933, "PREGABALIN": 1.4983751779348935, "PRITOR": 13.037516758579336, "REBETOL": 1.7490696187507446, "RETACRIT": 35.21142919167831, "REVLIMID": 3.001376011078795, "RIBAVIRIN": 4.367578418801494, "RITUXIMAB": 2.405757020561908, "ROACTEMRA": 1.7310611028219147, "RUBRACA": 1.5263948873435866, "RUFINAMIDE": 34.21217423825758, "RUXOLITINIB": 7.884389993030583, "SILDENAFIL": 2.348823763325063, "SIMPONI": 1.8230822724161664, "SOLIRIS": 1.3238249975965466, "SOVALDI": 1.6395771998637143, "SPRYCEL": 4.270333716845658, "STELARA": 4.146404401976492, "TASIGNA": 2.465877116490217, "THALIDOMIDE": 9.95303065310162, "TOBRAMYCIN": 3.680238891399501, "TOCILIZUMAB": 2.252527806287928, "TRACLEER": 2.285966424798865, "TREMFYA": 2.161102127496895, "TWINRIX": 12.092154713683705, "VFEND": 0.9465630818503414, "VORICONAZOLE": 2.2065954565963803, "VOTRIENT": 0.6956092398983077, "XELJANZ": 0.724528358487247, "XOLAIR": 1.5548870129611017, "XTANDI": 0.2765353749813926, "YESCARTA": 2.55516218822567, "ZARZIO": 5.864661449575679, "ZOSTAVAX": 0.1880477619166227, "null": 0.9392612212396504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11625.json
new file mode 100644
index 00000000000..26cec361bad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11625.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.3824076046093763, "AIMOVIG": 9.812006220172607, "ALEMTUZUMAB": 4.95754913166955, "ALIMTA": 5.731171086318192, "ALPELISIB": 19.354323675007983, "ARAVA": 0.4470567564582755, "ARIPIPRAZOLE": 1.2681260513489812, "AVASTIN": 5.4137034391108765, "AXITINIB": 35.50011037493099, "AZACITIDINE": 8.661754146913392, "BEVACIZUMAB": 15.201589276807466, "BORTEZOMIB": 31.07916673348921, "BOTULINUM": 6.332957648550714, "CAPECITABINE": 9.56290532868146, "CARFILZOMIB": 65.95567922975067, "CARMUSTINE": 13.8483616178848, "CELLCEPT": 4.372433897825553, "CICLOSPORIN": 1.1378092929345385, "COBIMETINIB": 27.37242856250962, "COMIRNATY": 0.1377789350894864, "COSENTYX": 0.928633715035325, "CYTARABINE": 7.576436500916198, "DABRAFENIB": 40.26413926134357, "DENOSUMAB": 10.429781614492136, "DEXAMETHASONE": 5.65847860530141, "DOCETAXEL": 7.709591095369095, "DOXORUBICIN": 8.310131859334078, "ENTYVIO": 3.8479512487290575, "FILGRASTIM": 13.53813885111127, "FULVESTRANT": 9.388942977353189, "HERCEPTIN": 3.295312851944208, "HUMAN": 14.262059114873663, "HUMIRA": 4.168359433284544, "IBRUTINIB": 25.24757006552831, "IBUPROFEN": 1.82816116899001, "ICLUSIG": 5.7934551053142505, "IRINOTECAN": 13.26078800277974, "KEYTRUDA": 15.826966533671126, "KISQALI": 7.451667199649868, "KYMRIAH": 4.801821557044752, "KYPROLIS": 14.653631436557214, "LEVETIRACETAM": 1.8248167680300007, "LUTETIUM": 29.74898920833145, "MABTHERA": 4.146999215443456, "MEKINIST": 2.9598817827229364, "METHOTREXATE": 1.6829892082898583, "NEXAVAR": 0.5409894114326493, "OBINUTUZUMAB": 17.4979119892943, "OMALIZUMAB": 2.8784627716174143, "PACLITAXEL": 17.959005945723682, "PANITUMUMAB": 74.4823847479434, "PAZOPANIB": 13.153834687498836, "PEGASYS": 0.4658779506036333, "PEGINTRON": 0.5021630659428539, "PEMBROLIZUMAB": 97.88908181114392, "PEMETREXED": 19.845889263031644, "RIBOCICLIB": 45.722913034238296, "RITUXIMAB": 9.65246853899483, "RUBRACA": 15.494220586701829, "RUXOLITINIB": 22.2700994895276, "SOTORASIB": 73.56637711356981, "SPIKEVAX": 0.1276498661787779, "TRODELVY": 9.699055877011729, "VAXZEVRIA": 0.0187639978779308, "VECTIBIX": 48.86753638740368, "VOTRIENT": 1.370836160197242, "XOLAIR": 1.063222270064397, "YESCARTA": 3.696353065879283, "null": 0.2021533999839939}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11626.json
new file mode 100644
index 00000000000..2057f6f84f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11626.json
@@ -0,0 +1 @@
+{"null": 0.7934161955149596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11627.json
new file mode 100644
index 00000000000..d170703521d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11627.json
@@ -0,0 +1 @@
+{"ABILIFY": 34.15946837796519, "ACLASTA": 42.750243205747225, "APIDRA": 4.782162122879303, "BUPRENORPHINE": 29.17939767715857, "CICLOSPORIN": 0.8120040368387769, "COMIRNATY": 0.1819004333391099, "FORTIMEL": 1213.750854150354, "HUMALOG": 1.9400576342518847, "IBRANCE": 1.0532991047725284, "PEGASYS": 0.7046402325643345, "QUTENZA": 69.85504554084534, "SPIKEVAX": 0.1655524277879061, "STELARA": 1.2290846012032712, "SUTENT": 1.378889076501771, "TOZINAMERAN": 0.5874428488480201, "VAXZEVRIA": 0.384517560521555, "XELJANZ": 1.2723753121543, "XOLAIR": 1.892407030522719, "null": 1.4226211711213406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11628.json
new file mode 100644
index 00000000000..618b28afd25
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11628.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3810194752464201, "SPIKEVAX": 0.3392695919283581, "TOZINAMERAN": 1.5180700560689795, "VAXZEVRIA": 1.7860223629618428, "null": 1.7025967353387876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11629.json
new file mode 100644
index 00000000000..cec22d052be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11629.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9321873061151504, "null": 1.2209032641920707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1163.json
index b3a6a375592..c7722da420e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1163.json
@@ -1 +1 @@
-{"ENTRESTO": 14.509370548118682}
\ No newline at end of file
+{"null": 1.9046738537938133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11630.json
new file mode 100644
index 00000000000..2d25fea8fb9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11630.json
@@ -0,0 +1 @@
+{"null": 2.212712716221833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11631.json
new file mode 100644
index 00000000000..8ee31fe1bec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11631.json
@@ -0,0 +1 @@
+{"ABILIFY": 6.094783991067126, "ARAVA": 0.9670499787641504, "ARIPIPRAZOLE": 3.885883841951277, "ATRIPLA": 0.0767154091021818, "BIKTARVY": 1.4712804039879692, "BRINTELLIX": 3.491508406348056, "BRIVIACT": 5.448614885860769, "BUPRENORPHINE": 1.8828102107468387, "CARIPRAZINE": 52.97794678812984, "CHAMPIX": 18.17537076495831, "COMIRNATY": 0.2353197267297801, "CYMBALTA": 3.737974687034054, "DULOXETINE": 4.826512456520859, "ELIQUIS": 0.2733206442233619, "FENTANYL": 0.5905587340297913, "HUMALOG": 1.4859677428212663, "IBRANCE": 1.065943706577389, "IBUPROFEN": 1.2287777480991948, "KEPPRA": 3.1131244035026677, "LANTUS": 1.043102088083666, "LATUDA": 7.239894630544351, "LEVETIRACETAM": 3.386492143518465, "LEVOFLOXACIN": 0.6812734302836058, "LYRICA": 6.1209288280584, "OLANZAPINE": 4.254518326017714, "OPSUMIT": 0.5952576714201921, "PEGASYS": 2.238463428566778, "PEGINTRON": 1.43276003161545, "SPIKEVAX": 0.2128653386407881, "SUBOXONE": 1.4736417529455117, "SUTENT": 0.4958042890158166, "TAMIFLU": 3.1230174259871117, "TOVIAZ": 1.848355811655803, "TOZINAMERAN": 0.9199764702337124, "VAXZEVRIA": 0.1310331230027511, "VIAGRA": 1.135085064290979, "XELJANZ": 0.6327934646007269, "XOLAIR": 0.5382466713543586, "XTANDI": 0.626669372432922, "XYREM": 3.0482230245428847, "ZYPREXA": 4.172988788802751, "null": 2.0363886548331727}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11632.json
new file mode 100644
index 00000000000..65ef7d2f361
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11632.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 611.3986152371257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11633.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11633.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11634.json
new file mode 100644
index 00000000000..c0ffc09c123
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11634.json
@@ -0,0 +1 @@
+{"null": 2.091031042875978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11635.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11635.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11636.json
new file mode 100644
index 00000000000..3f21ca868fc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11636.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.4195404099639288, "AFINITOR": 0.4301341038514805, "AIMOVIG": 0.5105838673169703, "APIDRA": 3.539781854397194, "ARAVA": 0.1385429051430231, "ARIPIPRAZOLE": 0.4085431572057596, "AUBAGIO": 0.3661152479553974, "BRAFTOVI": 0.8788282125234721, "BRINTELLIX": 0.6400355825978135, "BYDUREON": 0.764009288173042, "CHAMPIX": 2.370156846381854, "COMIRNATY": 0.8580869266400151, "COMTAN": 1.8543081112958897, "CYMBALTA": 0.7166086935398598, "DEXAMETHASONE": 0.3252582357537847, "ELIQUIS": 0.4516899191549463, "ELLAONE": 2.9726951049976704, "EMPAGLIFLOZIN": 13.086715335484769, "ENTRESTO": 0.8268048384881068, "EXFORGE": 0.6650841908156704, "FENTANYL": 1.2607909953597587, "FIASP": 4.1500756402321, "FORSTEO": 1.227779869648342, "FORXIGA": 11.010254166091208, "GARDASIL": 0.6599297943315401, "HUMALOG": 2.5034882916015917, "HYDROCORTISONE": 1.4887300174404845, "IBRANCE": 0.3779833001235699, "INCIVO": 1.210523745238247, "INSULIN": 1.4228686466366842, "JANUMET": 0.4348658475103097, "JANUVIA": 0.4330432135896127, "JARDIANCE": 15.86691686632605, "KALETRA": 0.554791501088654, "KEPPRA": 0.531920759452361, "KEYTRUDA": 0.919554581712635, "LANTUS": 2.5292985840013924, "LATUDA": 1.5154208144211136, "LYRICA": 0.4951028563381311, "MEKINIST": 0.4726716115459228, "MICARDIS": 0.8465002295752929, "MODERNA": 0.4706098533366811, "NOVORAPID": 0.4614818352944329, "OCRELIZUMAB": 4.193062384398799, "OLANZAPINE": 1.155293680076425, "OPDIVO": 0.8119601428057397, "PEGASYS": 0.983693425754408, "PEGINTRON": 2.452659173528025, "RELVAR": 2.8728566195327683, "RIBAVIRIN": 1.2046112041010626, "SAMSCA": 10.199955214385623, "SAXENDA": 1.3635934321825085, "SHINGRIX": 0.3284422421625926, "SPIKEVAX": 0.8147186295977393, "STELARA": 0.8174729005297232, "SUTENT": 0.1783488301943903, "TAMIFLU": 0.5666952324043348, "TELMISARTAN": 2.6013816464191817, "TOUJEO": 2.8953953280919102, "TOVIAZ": 8.227023601584046, "TOZINAMERAN": 1.4672712387525972, "TRULICITY": 0.5652024630932104, "VAXZEVRIA": 2.533452971106448, "XELJANZ": 0.2190216739530172, "XOLAIR": 0.2661576665845656, "XTANDI": 0.377097915251166, "ZOSTAVAX": 0.1842608351082937, "ZYPREXA": 2.762738917279277, "null": 0.8338723843225037}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11637.json
new file mode 100644
index 00000000000..00c74bec2a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11637.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8735970132671402, "MMRVAXPRO": 10.518567064610794, "SPIKEVAX": 0.3177469788548118, "VAXZEVRIA": 0.8361795128327687, "null": 0.9044602366630752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11638.json
new file mode 100644
index 00000000000..98095c3095d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11638.json
@@ -0,0 +1 @@
+{"null": 0.499960377561748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11639.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11639.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1164.json
index 671cf4833d8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1164.json
@@ -1 +1 @@
-{"SPIKEVAX": 35.15792648551141}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11640.json
new file mode 100644
index 00000000000..f6cc4db0a54
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11640.json
@@ -0,0 +1 @@
+{"SPRYCEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11641.json
new file mode 100644
index 00000000000..42266531b75
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11641.json
@@ -0,0 +1 @@
+{"null": 0.8740741756598425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11642.json
new file mode 100644
index 00000000000..056e5b4282b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11642.json
@@ -0,0 +1 @@
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11643.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11643.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11644.json
new file mode 100644
index 00000000000..f8fcf0a3a9e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11644.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1283337144327383, "null": 0.6229961337450646}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11645.json
new file mode 100644
index 00000000000..433c9561dfe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11645.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 5.002912434895226, "ATRIPLA": 6.744196250722952, "EVENITY": 118.69884794778946, "EVISTA": 79.50200247377553, "FORSTEO": 16.522823903008476, "STRIBILD": 3.348862490082252, "TRUVADA": 2.7155758793026887, "null": 0.7769504189115464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11646.json
new file mode 100644
index 00000000000..ead8725c17e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11646.json
@@ -0,0 +1 @@
+{"null": 0.6805743670107615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11647.json
new file mode 100644
index 00000000000..f9b024d7a13
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11647.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 113.99270689651637, "null": 1.3583056834776652}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11648.json
new file mode 100644
index 00000000000..9fbbc8f4b40
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11648.json
@@ -0,0 +1 @@
+{"null": 1.7094405736763596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11649.json
new file mode 100644
index 00000000000..048f42cf349
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11649.json
@@ -0,0 +1 @@
+{"null": 2.2434296420663644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1165.json
index cdc4ca73256..112a1cb32c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1165.json
@@ -1 +1 @@
-{"null": 1.3592101295242691}
\ No newline at end of file
+{"ARIPIPRAZOLE": 6.512937653076763, "COMIRNATY": 1.0591783287007317, "CYMBALTA": 1.0392187584260668, "FENTANYL": 4.744578589751511, "GARDASIL": 31.91917461103637, "LEVETIRACETAM": 2.060579054294554, "MIDAZOLAM": 8.421452998157308, "OLANZAPINE": 7.106430437170792, "SPIKEVAX": 0.5946784715558115, "TOZINAMERAN": 1.8906618941894229, "VAXZEVRIA": 0.4371898587879904, "ZYPREXA": 2.2989511702555423, "null": 0.8227159413795563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11650.json
new file mode 100644
index 00000000000..38d4c3f139c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11650.json
@@ -0,0 +1 @@
+{"REMICADE": 66.66758236181866, "null": 1.5492285891594504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11651.json
new file mode 100644
index 00000000000..6d6af66135b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11651.json
@@ -0,0 +1 @@
+{"ELIQUIS": 2.148294284052065, "FORSTEO": 3.730448881944247, "HUMALOG": 2.4846155435260826, "JANUVIA": 3.5396585189141927, "LANTUS": 2.446852851722716, "SUBOXONE": 3.4690739238878985, "TRELEGY": 12.647496975788384, "VIAGRA": 13.529051263072487, "XELJANZ": 1.3184416001204171, "XTANDI": 2.4759666002173493, "null": 3.488223854234567}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11652.json
new file mode 100644
index 00000000000..9217f2da0db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11652.json
@@ -0,0 +1 @@
+{"AUBAGIO": 3.1914935944227323, "AVAMYS": 205.74646166751603, "BUDESONIDE": 17.442777628617595, "COMIRNATY": 0.252250225341776, "ENTRESTO": 17.351382960204543, "MEPOLIZUMAB": 4.854488317434065, "OMALIZUMAB": 29.01487082333644, "SPIKEVAX": 0.1826133184568817, "TOZINAMERAN": 0.7626795199698482, "VARENICLINE": 251.59142101064495, "VAXZEVRIA": 0.1587963517529223, "XOLAIR": 7.0406736085255845, "null": 0.765575337292802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11653.json
new file mode 100644
index 00000000000..8d683ca7ee6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11653.json
@@ -0,0 +1 @@
+{"AERIUS": 1.6357270144903977, "AFINITOR": 0.2494509494256813, "AIMOVIG": 0.3741340389768178, "ALLERGY": 69.15917243321545, "ANORO": 1.756981899463859, "APROVEL": 1.3450850249873636, "ARAVA": 0.0875075974154562, "AUBAGIO": 0.2510693909653225, "AVAMYS": 3.262700337681529, "BENLYSTA": 1.5896185595234804, "BUDESONIDE": 0.4721903270334558, "BYDUREON": 0.3376911103670205, "CHAMPIX": 0.5359707170890435, "CICLOSPORIN": 0.2347744766112621, "CIMZIA": 0.3494794591756633, "CLOPIDOGREL": 0.248121081619565, "COMBIVIR": 0.7531779045986029, "COMIRNATY": 0.9593650891027647, "COSENTYX": 0.4335765442640006, "CYMBALTA": 0.0752462605448505, "DARZALEX": 2.277238179508255, "DEXAMETHASONE": 0.1993703459914458, "ELEBRATO": 31.089914454059905, "ELIQUIS": 0.5222733373545223, "ENBREL": 0.2423689257630163, "ENTRESTO": 0.5127304292168148, "ENTYVIO": 0.6910179146035516, "ESBRIET": 0.6982797043797582, "EVISTA": 0.713284866163675, "EXFORGE": 0.9701569594852584, "EXJADE": 0.6184500215983352, "FASENRA": 1.6381729261091436, "FASLODEX": 1.984252788434932, "FENTANYL": 0.2002611367526549, "FORSTEO": 0.4889763933166413, "GARDASIL": 0.4521965118715798, "HIZENTRA": 0.7537872076679611, "HUMALOG": 0.1289259099318131, "HYDROCORTISONE": 1.0207689096144097, "IBRANCE": 0.64823670486273, "INCRUSE": 4.328323319820536, "INLYTA": 0.4960382209873802, "JANUVIA": 0.2396179059823798, "JARDIANCE": 0.2884563440303764, "KEPPRA": 0.1991562840839166, "KESIMPTA": 2.211219098823108, "KEYTRUDA": 0.1170888196092205, "LANTUS": 0.1247823636311364, "LEVETIRACETAM": 0.290475312184154, "LEVOFLOXACIN": 0.1863915363826212, "MENVEO": 1.404637111919131, "MEPOLIZUMAB": 0.6774250143874497, "MICARDIS": 0.643036703893651, "MMRVAXPRO": 0.1974571461069419, "MODERNA": 0.8979973219346238, "NAGLAZYME": 1.0215077048455796, "NIMENRIX": 0.5529660081573445, "NUCALA": 1.0529928928305163, "OFATUMUMAB": 12.142701430593592, "OFEV": 0.9604647197122484, "OMALIZUMAB": 1.7340366091230754, "ONCASPAR": 1.596742508298315, "OPSUMIT": 0.7510143904785624, "PANTOPRAZOLE": 0.7595836778521847, "PEGASYS": 0.4323704418681091, "PEGINTERFERON": 0.4061790751724804, "PEGINTRON": 0.3530310068143847, "PLAVIX": 0.2936878767090998, "PRIVIGEN": 1.417229862573803, "QUTENZA": 23.15140497049723, "RELVAR": 10.43334403567379, "RINVOQ": 0.8124369652449609, "RITUXIMAB": 2.589961826478061, "RIXATHON": 25.85324246592377, "ROACTEMRA": 0.8662715990036234, "SHINGRIX": 0.4803353629443834, "SIMPONI": 0.3383067095662651, "SPIKEVAX": 0.4591283748820061, "STELARA": 0.3526887935253943, "SUTENT": 0.5944469029914735, "TAMIFLU": 0.4304843204663137, "TOVIAZ": 0.7013246248619378, "TOZINAMERAN": 1.5216320811711368, "TRACLEER": 0.6319370245748359, "TRELEGY": 4.502472057164679, "VAXZEVRIA": 0.4155416404912141, "VOTRIENT": 0.8577925568796656, "XELJANZ": 0.7907476570158394, "XOLAIR": 4.394188159004771, "XTANDI": 1.0232922704937335, "null": 2.905860235753634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11654.json
new file mode 100644
index 00000000000..cecb57d73c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11654.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2217707379252678, "SUTENT": 12.908766415428609, "null": 1.1370822181662914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11655.json
new file mode 100644
index 00000000000..964f63e297c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11655.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11656.json
new file mode 100644
index 00000000000..e25994cddbc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11656.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6044341854347024, "ELIQUIS": 22.08974646073034, "SPIKEVAX": 2.097386340285113, "VAXZEVRIA": 0.6320144208567909, "null": 0.2940808577404701}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11657.json
new file mode 100644
index 00000000000..4f7cb8d6fae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11657.json
@@ -0,0 +1 @@
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11658.json
new file mode 100644
index 00000000000..8a79f9dd0a5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11658.json
@@ -0,0 +1 @@
+{"NOVORAPID": 119.55129545834102, "null": 0.828117545166916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11659.json
new file mode 100644
index 00000000000..873833adf52
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11659.json
@@ -0,0 +1 @@
+{"null": 0.8008872523376593}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1166.json
index d31020f9986..04877dd2ba2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1166.json
@@ -1 +1 @@
-{"HEPSERA": 225.6894386343257}
\ No newline at end of file
+{"COMIRNATY": 0.3321965879537429, "EMTRIVA": 194.14946612919385, "GARDASIL": 23.450875887580985, "HUMALOG": 3.841306587036304, "TELMISARTAN": 85.42130020171288, "TOZINAMERAN": 0.9398397884572016, "ZOSTAVAX": 5.283170520147827, "null": 0.8371966108409227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11660.json
new file mode 100644
index 00000000000..f7073404be5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11660.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11661.json
new file mode 100644
index 00000000000..55e3ae5c21f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11661.json
@@ -0,0 +1 @@
+{"COMBIVIR": 73.11391863051134, "null": 2.4683851349701933}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11662.json
new file mode 100644
index 00000000000..a81586f50c2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11662.json
@@ -0,0 +1 @@
+{"BEVACIZUMAB": 4.073826077222182, "CICLOSPORIN": 1.1944461724751931, "CLOPIDOGREL": 1.3990526127833398, "COAPROVEL": 7.525388993845739, "COMIRNATY": 0.3460605164508733, "GARDASIL": 2.1534052927377694, "KEPPRA": 1.6754070993879209, "MICARDIS": 5.8236097052608775, "MMRVAXPRO": 2.4357431484741, "PEGASYS": 3.114171628324546, "PLAVIX": 11.59214598646411, "PREVENAR": 44.67837880908317, "ROTATEQ": 34.92222192097596, "SPIKEVAX": 0.13744839279822, "SUTENT": 0.8423424862667175, "TOZINAMERAN": 0.1884630481317041, "VAXZEVRIA": 0.2193083919825198, "null": 2.429863575352777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11663.json
new file mode 100644
index 00000000000..21bbe0a967c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11663.json
@@ -0,0 +1 @@
+{"CIMZIA": 0.8184385368147672, "COMIRNATY": 0.249533621680962, "ELIQUIS": 1.2062214500532504, "ENOXAPARIN": 7.776974941528864, "EXJADE": 3.0095814861494827, "JAKAVI": 29.97246885467474, "NILOTINIB": 15.432165365654727, "NPLATE": 43.84949571751786, "PEGASYS": 1.2995685501767067, "PLAVIX": 0.7653432025903627, "RUXOLITINIB": 30.277601068635413, "SPIKEVAX": 0.1490135456687087, "STELARA": 0.9989454503200628, "SUTENT": 1.5769405752238064, "TASIGNA": 8.86397905567226, "VAXZEVRIA": 0.2723008003441299, "XELJANZ": 0.6272405015974488, "ZYPREXA": 2.285253523483035, "null": 1.5621791172301585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11664.json
new file mode 100644
index 00000000000..115c7017e03
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11664.json
@@ -0,0 +1 @@
+{"null": 0.5347424042529709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11665.json
new file mode 100644
index 00000000000..2d31c57bccc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11665.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8958083419077377, "VAXZEVRIA": 1.1077818757728382, "null": 0.2695987820297142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11666.json
new file mode 100644
index 00000000000..0ebdbad73ec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11666.json
@@ -0,0 +1 @@
+{"ARANESP": 1.4952573499444517, "AVASTIN": 2.836003770832646, "CELECOXIB": 9.611690427339337, "COMIRNATY": 1.9336481372493957, "DEXAMETHASONE": 1.6248948550044793, "ELIQUIS": 0.8118594962930424, "EVISTA": 8.31102206815091, "FORSTEO": 4.319420273354766, "FULVESTRANT": 5.550895742559134, "MODERNA": 1.6570300641352504, "PEGASYS": 0.8639319776741166, "PEGINTERFERON": 1.4661821805080348, "PEGINTRON": 1.6769922758037124, "ROACTEMRA": 1.2452863046539575, "SIMPONI": 0.8888662139737016, "SPIKEVAX": 0.7506095176261773, "STELARA": 0.4586707731132417, "TOZINAMERAN": 0.3535987854526635, "VAXZEVRIA": 2.5520510126368454, "XELJANZ": 0.7184513876462346, "ZYPREXA": 0.8269070279678103, "null": 0.7418698902997287}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11667.json
new file mode 100644
index 00000000000..ee1000b192e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11667.json
@@ -0,0 +1 @@
+{"ALIMTA": 30.041564853641983, "KEYTRUDA": 46.01875719887684, "OPDIVO": 42.0414189899959, "null": 0.3402689028585037}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11668.json
new file mode 100644
index 00000000000..8e5309259bd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11668.json
@@ -0,0 +1 @@
+{"null": 1.02079846655359}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11669.json
new file mode 100644
index 00000000000..2f7b518200c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11669.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.2348086115983552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1167.json
index 5e9bee39fc4..67547d3eebd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1167.json
@@ -1 +1 @@
-{"ANAKINRA": 3.7484852172391294, "APROVEL": 4.359030178857514, "ARANESP": 128.66668450380837, "BRILIQUE": 11.002778726767062, "CELLCEPT": 1.371465896526329, "CICLOSPORIN": 1.9699394981540024, "COAPROVEL": 12.075710679106928, "CYMBALTA": 1.1706872862046585, "DARBEPOETIN": 80.88319461086844, "EMPAGLIFLOZIN": 8.696923788584629, "ENTRESTO": 5.993897309208055, "EXFORGE": 3.476014068825986, "EXJADE": 1.3473071021045386, "FASTURTEC": 59.56608188824778, "FEBUXOSTAT": 10.315619217620414, "FORSTEO": 7.3133874597412465, "INCIVO": 10.641717064275609, "JAKAVI": 2.064666973283669, "MELATONIN": 8.691400737340238, "MICARDIS": 6.080403160675028, "OZEMPIC": 20.203067981678025, "PEGASYS": 2.2211819539518656, "PEGINTERFERON": 4.5403269253159015, "PEGINTRON": 6.849380935879915, "RASILEZ": 7.805911395008172, "REBETOL": 6.69092896809856, "SUTENT": 2.141116813551358, "VENETOCLAX": 5.924699836168286, "null": 1.0068389811757723}
\ No newline at end of file
+{"null": 1.9055590010609664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11670.json
new file mode 100644
index 00000000000..2aaf1214da3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11670.json
@@ -0,0 +1 @@
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0.1274490450215389, "PEGASYS": 0.7047030450670376, "PEGINTRON": 0.4348428603891247, "PLAVIX": 2.866256195308674, "PRADAXA": 0.8856326441878271, "PRIVIGEN": 0.919540340262663, "RAPAMUNE": 1.35619276129087, "REMICADE": 0.7962467229468577, "REVATIO": 1.4061146736597407, "REVLIMID": 5.232603298701995, "RINVOQ": 3.3502237626978366, "RITUXIMAB": 0.3395836259222595, "RIVAROXABAN": 5.257176858496522, "ROACTEMRA": 0.6695846636665548, "RUBRACA": 0.5380600129422825, "RUCONEST": 6.541343816846738, "SAXENDA": 0.177235278968926, "SHINGRIX": 0.1751757398281851, "SIMPONI": 0.6614431035148741, "SOLIRIS": 2.201730698082283, "SPIKEVAX": 0.7794866229344619, "SPINRAZA": 0.6313722759848681, "SPRYCEL": 0.7595331914416757, "STELARA": 0.9294333928467308, "STIVARGA": 0.1267391810766967, "SUBOXONE": 0.4466943515695032, "SUTENT": 1.2025547163557924, "TAGRISSO": 1.6087327624786611, "TAMIFLU": 0.1767918788691399, "TASIGNA": 0.8234023208041562, "TESTOSTERONE": 2.8968926194906124, "THALIDOMIDE": 1.2047745836864625, "TICAGRELOR": 0.5392734223227257, "TORISEL": 0.8247432289712028, "TOVIAZ": 0.8291938869355283, "TOZINAMERAN": 2.639101132636042, "TRACLEER": 0.4490092086054273, "TRELEGY": 1.3146264335632687, "TREMFYA": 1.0053609239443797, "TRULICITY": 0.4793200081497946, "VAXZEVRIA": 1.665244376247219, "VEKLURY": 1.3964187607195908, "VELTASSA": 2.3351573519179567, "VFEND": 0.7640444675643556, "VIAGRA": 1.184284528649743, "VICTOZA": 0.3699073844106916, "VOTRIENT": 1.7010213510626575, "XALKORI": 2.7876026998942804, "XARELTO": 3.617483521030592, "XELJANZ": 2.9075950038944147, "XELODA": 0.7879279523158312, "XOLAIR": 0.784641647815069, "XTANDI": 0.8249131080692672, "XYREM": 0.5325902815855132, "YERVOY": 0.5890389197119226, "ZOSTAVAX": 0.4239562927297811, "ZYPREXA": 0.4298631484848577, "null": 0.8965772773222765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11671.json
new file mode 100644
index 00000000000..43b09f9f661
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11671.json
@@ -0,0 +1 @@
+{"ANGIOX": 1411.7258483360908, "BRILIQUE": 25.474311601385647, "CLOPIDOGREL": 19.26054780031012, "COMIRNATY": 0.0461375712256501, "EFIENT": 54.40024469405927, "ELIQUIS": 1.118511149140483, "INTEGRILIN": 57.21520619148361, "NOVOSEVEN": 36.71735091326151, "OPSUMIT": 6.656899641547017, "PLAVIX": 35.794174963850004, "TOZINAMERAN": 0.3423210695810065, "VAXZEVRIA": 0.7546646288812853, "null": 1.0127766028425884}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11672.json
new file mode 100644
index 00000000000..5312d8592e4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11672.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 1.6857476404880682, "null": 0.6182810276892982}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11673.json
new file mode 100644
index 00000000000..f49f2badccf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11673.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9573030157546656, "SPIKEVAX": 0.6066126687675907, "TOZINAMERAN": 0.5571758900116361, "VAXZEVRIA": 32.32035859550954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11674.json
new file mode 100644
index 00000000000..3fd4727c855
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11674.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8574583084322458, "EYLEA": 36.69414944406294, "FORXIGA": 40.03071790110597, "NEXAVAR": 10.021200334572695, "null": 0.3755691459570104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11675.json
new file mode 100644
index 00000000000..7f897638545
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11675.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.5859664630303251, "AFINITOR": 0.7049191312081077, "ALEMTUZUMAB": 15.464088598319258, "ALIMTA": 1.783574744600472, "AVASTIN": 2.611264195661572, "AZATHIOPRINE": 7.9997095510508, "BARACLUDE": 17.811544225557494, "BASILIXIMAB": 30.361179545275668, "BETAFERON": 10.124776492912403, "BEVACIZUMAB": 4.166217935927997, "BORTEZOMIB": 16.775965057481343, "BUSILVEX": 42.7143209847935, "BUSULFAN": 59.18989048012737, "CARFILZOMIB": 86.18335270529403, "CELLCEPT": 18.14485455561235, "CICLOSPORIN": 32.44036487930923, "CLOPIDOGREL": 0.4795499693248395, "COMIRNATY": 0.0508140339664644, "CYTARABINE": 1.3880859792394769, "DARZALEX": 2.99515742442458, "DEFITELIO": 51.15663056011521, "DEXAMETHASONE": 2.3023607065883103, "DINUTUXIMAB": 63.43992733938562, "ECULIZUMAB": 112.3892235278637, "GANCICLOVIR": 57.91471253342652, "ICLUSIG": 2.9541735766336026, "JAKAVI": 2.052963783060541, "KEYTRUDA": 0.4606254359703752, "KYPROLIS": 98.46651724580556, "LAMIVUDINE": 4.217252247993341, "MELPHALAN": 57.31363703392644, "METHOTREXATE": 2.899921193869577, "MYCOPHENOLATE": 11.557000540945156, "PEGASYS": 0.3231690605074375, "RAPAMUNE": 17.69832113023242, "SOLIRIS": 55.74045386304496, "SPIKEVAX": 0.0410566144966529, "SUNITINIB": 30.93138083052052, "SUTENT": 2.288192137363575, "TACROLIMUS": 24.854055910318632, "THIOTEPA": 28.27481572516789, "VAXZEVRIA": 0.0228885593250526, "VOTRIENT": 1.7466575589354014, "null": 0.500408219064186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11676.json
new file mode 100644
index 00000000000..fd3f667a085
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11676.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4172392817197601, "ELIQUIS": 6.017952428414675, "NOVOSEVEN": 202.00877410635283, "TOZINAMERAN": 1.3300308031368282, "VAXZEVRIA": 0.855406276245695, "null": 0.6524233829843953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11677.json
new file mode 100644
index 00000000000..5ece288cb76
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11677.json
@@ -0,0 +1 @@
+{"ALIMTA": 2.457834580901952, "AVASTIN": 3.4473869441765035, "BORTEZOMIB": 12.185058020817925, "BUSULFAN": 9.791256126763768, "CELLCEPT": 3.316708129116423, "CICLOSPORIN": 8.241681081605687, "CLOPIDOGREL": 11.52768710071464, "COMIRNATY": 0.2170779797544822, "KEYTRUDA": 0.7190932816458795, "KYPROLIS": 29.521433685834456, "LEMTRADA": 4.93767380130779, "PEGASYS": 3.595159884021149, "PEGINTERFERON": 4.45445813904927, "PEGINTRON": 4.25788171645187, "PLAVIX": 68.74921420691922, "SOLIRIS": 3.3505197364234096, "SPIKEVAX": 0.2155663040679871, "SUTENT": 2.1411978385745587, "TICAGRELOR": 6.361380751466973, "TOZINAMERAN": 0.5908053600597885, "VAXZEVRIA": 0.226293769586691, "ZOSTAVAX": 1.2067519340806387, "null": 0.7448116980030758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11678.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11678.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11679.json
new file mode 100644
index 00000000000..fc9d4b355be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11679.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.3547383798197554, "TOZINAMERAN": 3.101041709969715, "VAXZEVRIA": 3.0823677422193008, "null": 0.4624104912122391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1168.json
index 321514befd1..6655d12098a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1168.json
@@ -1 +1 @@
-{"COVID19": 1.3152597365088137, "SUTENT": 7.691889612945651, "TOZINAMERAN": 1.668810133732888}
\ No newline at end of file
+{"AZATHIOPRINE": 166.42401985200956, "COMIRNATY": 0.2310006943051132, "SPIKEVAX": 0.5004144063775879, "TOZINAMERAN": 2.8255565826074887, "VAXZEVRIA": 1.415409821898588, "null": 0.7081585314814612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11680.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11680.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11681.json
new file mode 100644
index 00000000000..f9994789336
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11681.json
@@ -0,0 +1 @@
+{"null": 0.8795178211584224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11682.json
new file mode 100644
index 00000000000..e6abae2667b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11682.json
@@ -0,0 +1 @@
+{"COMTAN": 256.7979562969939, "null": 1.544843784942001}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11683.json
new file mode 100644
index 00000000000..2bd8fa38daa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11683.json
@@ -0,0 +1 @@
+{"null": 0.6671588520219112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11684.json
new file mode 100644
index 00000000000..ea925d09ca1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11684.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 2467.4379959956373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11685.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11685.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11686.json
new file mode 100644
index 00000000000..d4ef60cab28
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11686.json
@@ -0,0 +1 @@
+{"null": 0.9953854686386888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11687.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11687.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11688.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11688.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11689.json
new file mode 100644
index 00000000000..40c6742b0b8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11689.json
@@ -0,0 +1 @@
+{"null": 1.694721013906438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1169.json
index 921378b1692..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1169.json
@@ -1 +1 @@
-{"AFINITOR": 2.5053126709686, "ALEMTUZUMAB": 10.536571524487783, "BETMIGA": 6.610177408113944, "BRILIQUE": 1.162311113960982, "CHAMPIX": 1.0727132995790218, "CLOPIDOGREL": 1.705838480879745, "DULOXETINE": 6.927795571262581, "ELIQUIS": 10.853187012113892, "ESBRIET": 1.7782474586540955, "EXJADE": 2.799774651437241, "FORXIGA": 1.3788942636601598, "HEMLIBRA": 12.771701943754934, "HUMIRA": 1.0081904039408287, "INLYTA": 1.3611506276495169, "JARDIANCE": 2.126059874790397, "LEMTRADA": 3.8282215603305447, "LIXIANA": 35.401728374591656, "LYRICA": 1.497612094923526, "OMALIZUMAB": 4.195451152866994, "PEGASYS": 1.9981971953597024, "PLAVIX": 3.772079829271092, "RIBAVIRIN": 1.243198497682054, "RITUXIMAB": 1.7164707935573895, "SILDENAFIL": 2.154138867592138, "SOLIRIS": 4.958396586578211, "STELARA": 1.130562413396184, "SUTENT": 4.38386728486451, "TOVIAZ": 6.4138136772640895, "TOZINAMERAN": 1.0712945867428605, "VIAGRA": 3.7674588622550753, "VOTRIENT": 3.691495286575616, "XARELTO": 12.087292543389566, "XELJANZ": 1.4221420626286738, "XTANDI": 10.157948898610009}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11690.json
new file mode 100644
index 00000000000..20708690edd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11690.json
@@ -0,0 +1 @@
+{"ARAVA": 0.895088309194932, "AVAMYS": 2.525794753697124, "BYDUREON": 3.712686573625516, "BYETTA": 42.425484437229386, "CELLCEPT": 1.3225692724315623, "CIMZIA": 0.6596025561650846, "COMIRNATY": 0.0345330734284073, "COSENTYX": 1.5600809185657356, "ELIQUIS": 0.3507588656868844, "ENBREL": 1.043002973924937, "EXFORGE": 2.604958340625363, "HUMALOG": 1.6384355399377617, "HUMIRA": 1.6996454496243287, "IBRANCE": 0.5611575600569525, "JANUMET": 5.521870911840977, "JANUVIA": 1.835491272299531, "LANTUS": 2.114836678926606, "LEMTRADA": 4.484581217835413, "MEKINIST": 4.018593311506203, "NEXAVAR": 13.379094114689812, "ROACTEMRA": 2.865424938470897, "SAXENDA": 10.415305713153726, "SIMPONI": 2.6258129615008894, "STELARA": 4.321058994357875, "SUTENT": 0.709635375498122, "TRULICITY": 11.520853832466871, "VICTOZA": 15.583297443412546, "XELJANZ": 0.5832941195876012, "XOLAIR": 2.2299419951494794, "ZOSTAVAX": 0.8251366033686103, "null": 2.23019511573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11691.json
new file mode 100644
index 00000000000..1384d019e96
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11691.json
@@ -0,0 +1 @@
+{"BYETTA": 40.7296587505901, "CICLOSPORIN": 20.11618641620971, "NEXAVAR": 93.56880461316815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11692.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11692.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11693.json
new file mode 100644
index 00000000000..099b5b63b97
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11693.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6834395478487275, "null": 0.6986203070224101}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11694.json
new file mode 100644
index 00000000000..75cbc81aecd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11694.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.5629659500872425, "AIMOVIG": 0.5466257444309276, "ALEMTUZUMAB": 1.678734908760498, "APIDRA": 0.8531270392818947, "ARAVA": 1.5295383749954607, "AUBAGIO": 0.5151047726100324, "AVAMYS": 4.256288605575644, "AVANDIA": 0.3917210400878245, "AXITINIB": 4.204079321279239, "BYDUREON": 1.0683768358855577, "BYETTA": 1.1981541033089098, "CABOMETYX": 6.2736237387698965, "CHAMPIX": 0.7398862198782056, "CIMZIA": 0.5497698643574104, "CLOPIDOGREL": 0.4412144439426723, "COMIRNATY": 0.3226407449803348, "COSENTYX": 0.4590848102647388, "CYMBALTA": 0.5961071493174896, "ELIQUIS": 1.7569838455328168, "ENBREL": 0.7367713629403868, "ESOMEPRAZOLE": 3.087174362446939, "EXFORGE": 1.4429739584171697, "FAMPYRA": 1.44248371586788, "FORSTEO": 1.1456470737050737, "GARDASIL": 0.4488619640165213, "HARVONI": 2.6469330240135944, "HUMALOG": 6.992258380853155, "HUMIRA": 0.6105372650031008, "IBRANCE": 0.9008734751859554, "INLYTA": 6.51713019786418, "INSULIN": 1.8232805600995865, "INTRONA": 3.335622607398148, "IPILIMUMAB": 4.45171356922315, "JANUMET": 1.0291708708407297, "JANUVIA": 1.4022705348020414, "KEPPRA": 0.2633971884372961, "KEYTRUDA": 11.238894508797744, "LANTUS": 1.7023318218701209, "LEMTRADA": 16.254940210782458, "LYRICA": 0.6288230353444307, "METHOTREXATE": 0.8057900509107617, "NUCALA": 0.6345337499877721, "OPDIVO": 13.751972503811968, "OPSUMIT": 0.7145620802141404, "PEGASYS": 4.371569488329394, "PEGINTRON": 3.411711297197196, "PEMBROLIZUMAB": 1.3262247038847097, "PLAVIX": 0.5978851192593759, "SAXENDA": 1.561291998425419, "SIMPONI": 0.8801470780410086, "SPIKEVAX": 0.1351454426450534, "STELARA": 0.8303406857933525, "SUTENT": 9.350701788490214, "TOZINAMERAN": 0.269732129397853, "TRULICITY": 1.1161903275390814, "VAXZEVRIA": 0.0914346483091608, "VIAGRA": 1.0005394098138611, "VICTOZA": 1.9614675158750332, "VOTRIENT": 1.4559942595383992, "XELJANZ": 1.7604369686780708, "XOLAIR": 0.7363920719906294, "YERVOY": 6.7735081084961655, "ZOSTAVAX": 4.53313121855161, "ZYPREXA": 0.3124440262148911, "null": 1.1362081709068534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11695.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11695.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11696.json
new file mode 100644
index 00000000000..b7bc3528029
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11696.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1124236650330583, "KEYTRUDA": 5.692518775649711, "LEMTRADA": 21.81544765764171, "LYRICA": 5.147317622658074, "PEGASYS": 9.533002508274675, "PEGINTRON": 3.3548828495788072, "SUTENT": 10.948351156676772, "VOTRIENT": 4.674602976227767, "null": 1.02356959022674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11697.json
new file mode 100644
index 00000000000..90fada2f889
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11697.json
@@ -0,0 +1 @@
+{"null": 0.9567157319567168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11698.json
new file mode 100644
index 00000000000..f3d633b64b1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11698.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 14.119896063107138, "null": 0.6158094656152134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11699.json
new file mode 100644
index 00000000000..684383114ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11699.json
@@ -0,0 +1 @@
+{"CABOMETYX": 19.10873231146001, "COMIRNATY": 0.4394531407293071, "KEYTRUDA": 8.041047766133515, "LEMTRADA": 23.092107926950558, "PEGASYS": 4.458305022485583, "SUTENT": 3.547523108168235, "null": 0.7675652211136141}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/117.json
index 3e8cef0e15d..32665cc1673 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/117.json
@@ -1 +1 @@
-{"CYMBALTA": 8.636184020815891, "LATUDA": 91.89019179892796, "null": 6.294233900142147}
\ No newline at end of file
+{"ABILIFY": 4.315958784874212, "BRINTELLIX": 6.154651916865296, "CHAMPIX": 2.200870636577734, "COMIRNATY": 0.4601106122053701, "CYMBALTA": 1.2341572976713968, "QARZIBA": 114.14679605699676, "SPIKEVAX": 0.3597975007801347, "VAXZEVRIA": 0.386658195985076, "null": 3.0469030029645414}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1170.json
index 4b68db5d56c..fece3e7f509 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1170.json
@@ -1 +1 @@
-{"null": 1.624882968930519}
\ No newline at end of file
+{"LATUDA": 58.86945696779946, "null": 0.9274912096037992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11700.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11700.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11701.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11701.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11702.json
new file mode 100644
index 00000000000..71f00412ad9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11702.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.4461577704806861, "ADEMPAS": 14.75452783090638, "BYDUREON": 9.405889231440277, "BYETTA": 19.895979414458694, "COMIRNATY": 0.4249594304991849, "CYMBALTA": 1.1884463648120374, "ELIQUIS": 0.6374583615975653, "FASLODEX": 3.2997800438943083, "FORSTEO": 2.67737949605418, "GARDASIL": 1.0551561928365782, "IBRANCE": 1.7198655564043006, "JANUMET": 2.828308870888591, "JANUVIA": 4.105133675601592, "JARDIANCE": 1.7919113262819488, "LEMTRADA": 5.482863979626599, "SAXENDA": 18.97454354213747, "SPIKEVAX": 0.2479045313294608, "STELARA": 1.1900288927732758, "TOZINAMERAN": 0.274260081934625, "TRULICITY": 5.935347573442068, "VAXZEVRIA": 0.1790356365922661, "VICTOZA": 26.638531864095597, "XELJANZ": 1.5974936654849266, "ZOSTAVAX": 6.58826997794847, "null": 0.8512012947877047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11703.json
new file mode 100644
index 00000000000..01f8ea1b900
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11703.json
@@ -0,0 +1 @@
+{"ARAVA": 9.98085421735212, "AVAMYS": 13.722803177905666, "BYETTA": 9.93728604066932, "TRULICITY": 20.47303134348697, "VICTOZA": 40.037535085646354, "null": 0.5553894991405038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11704.json
new file mode 100644
index 00000000000..ad74792f2a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11704.json
@@ -0,0 +1 @@
+{"NUCALA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11705.json
new file mode 100644
index 00000000000..3b80df7259a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11705.json
@@ -0,0 +1 @@
+{"JANUMET": 29.29206945646854, "null": 0.7936388622360223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11706.json
new file mode 100644
index 00000000000..69f31e2045d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11706.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.733186773169338, "SPIKEVAX": 1.2139916740540897, "TOZINAMERAN": 2.478072732232738, "VAXZEVRIA": 1.4373355739916631, "null": 0.2456137875749109}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11707.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11707.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11708.json
new file mode 100644
index 00000000000..93fc2fcbcca
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11708.json
@@ -0,0 +1 @@
+{"LEMTRADA": 1033.8778732406265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11709.json
new file mode 100644
index 00000000000..149c89ee9f8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11709.json
@@ -0,0 +1 @@
+{"AVAMYS": 12.096223340649193, "BYETTA": 9.939138463734446, "CICLOSPORIN": 7.746725943118849, "JANUMET": 12.682783019095847, "LEMTRADA": 20.328285574759636, "OPSUMIT": 7.009903114418974, "ZOSTAVAX": 4.37853122743919, "null": 1.0062260092767163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1171.json
index 0f6eb638079..82db82339a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1171.json
@@ -1 +1 @@
-{"CYMBALTA": 11.110791152787844, "ELIQUIS": 7.758519755910308, "null": 1.1151034971119689}
\ No newline at end of file
+{"ATRIPLA": 24.29557802455055, "TRUVADA": 9.633760360102928, "null": 0.3888757192717942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11710.json
new file mode 100644
index 00000000000..69e53d6d59a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11710.json
@@ -0,0 +1 @@
+{"AXITINIB": 18.149196867009262, "BAVENCIO": 37.2716292013344, "CABOMETYX": 9.303776191789808, "COMIRNATY": 0.5671867003579999, "INLYTA": 9.683328444485342, "IPILIMUMAB": 70.05052279764486, "IRBESARTAN": 5.78630768753406, "KEYTRUDA": 39.6945164565048, "LEMTRADA": 16.647929482522013, "LENVIMA": 6.217118023287381, "NEXAVAR": 1.240490381947311, "NIVOLUMAB": 22.155168635566707, "OPDIVO": 65.88600664414933, "PACLITAXEL": 7.414635514765443, "PEGASYS": 5.011843303437852, "PEGINTERFERON": 3.3266136747177044, "PEGINTRON": 6.9752149101148815, "PEMBROLIZUMAB": 18.042315370165326, "SPIKEVAX": 0.2887401037161858, "SUTENT": 1.1079336379287974, "TASIGNA": 1.7848271115605412, "TOZINAMERAN": 0.5214797082536855, "VAXZEVRIA": 0.2088526981844684, "YERVOY": 6.955764566201648, "null": 0.5526080748530278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11711.json
new file mode 100644
index 00000000000..5d67030f208
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11711.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.1317968045313127, "PEGASYS": 5.4604569705428805, "VAXZEVRIA": 0.963408277441216, "null": 0.2189543773822248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11712.json
new file mode 100644
index 00000000000..3a75469ab41
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11712.json
@@ -0,0 +1 @@
+{"null": 0.7809000972385235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11713.json
new file mode 100644
index 00000000000..93a59b16739
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11713.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.140267864922886, "KEYTRUDA": 2.6348635511817737, "LEMTRADA": 12.849524972374889, "OPDIVO": 7.0407337600354944, "PEGASYS": 1.6498152514320945, "SPIKEVAX": 2.0152795749285035, "TOZINAMERAN": 5.14619880374188, "VAXZEVRIA": 0.8491248825226309, "null": 0.1271824883787814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11714.json
new file mode 100644
index 00000000000..fdaf6903436
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11714.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2476715929225958, "FENTANYL": 4.650816953229605, "HYDROCORTISONE": 15.281199487922304, "IPILIMUMAB": 16.00775582564924, "KEYTRUDA": 9.139658411819342, "OPDIVO": 12.941417456050493, "TOZINAMERAN": 0.8403943483873338, "null": 1.7166880592025675}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11715.json
new file mode 100644
index 00000000000..b86aa0dff3d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11715.json
@@ -0,0 +1 @@
+{"null": 0.7775215640317513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11716.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11716.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11717.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11717.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11718.json
new file mode 100644
index 00000000000..0b459841180
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11718.json
@@ -0,0 +1 @@
+{"null": 1.1870177049144868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11719.json
new file mode 100644
index 00000000000..c3ed69a1ee4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11719.json
@@ -0,0 +1 @@
+{"ARAVA": 1.2111011590129157, "ARIPIPRAZOLE": 69.8295287952067, "LEMTRADA": 55.69847189331709, "SUTENT": 5.488841188910136, "null": 1.1881083066291067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1172.json
index 3a4401ee8c4..2f9776f67c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1172.json
@@ -1 +1 @@
-{"HUMALOG": 27.84800049505192}
\ No newline at end of file
+{"ANAKINRA": 171.9747593651108, "CIMZIA": 68.6573289879897, "SIMPONI": 19.78909575832424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11720.json
new file mode 100644
index 00000000000..d568691ce37
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11720.json
@@ -0,0 +1 @@
+{"LEMTRADA": 302.4273125490369}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11721.json
new file mode 100644
index 00000000000..2d02672d5a3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11721.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1360499370013361, "KEYTRUDA": 5.20156290134426, "LEMTRADA": 57.141289884912666, "null": 2.502275544324392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11722.json
new file mode 100644
index 00000000000..8b989e7ec61
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11722.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.121027399187327, "KEYTRUDA": 6.189140376749272, "LEMTRADA": 63.975257517751785, "null": 2.4870759780799383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11723.json
new file mode 100644
index 00000000000..cab2825a688
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11723.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1386728058582563, "LEMTRADA": 71.30359012543038, "PEGASYS": 3.674212625672781, "null": 2.1084700305608237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11724.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11724.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11725.json
new file mode 100644
index 00000000000..24b5c6db6ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11725.json
@@ -0,0 +1 @@
+{"ATRIPLA": 21.432927446876384, "ELIQUIS": 0.9747537928857982, "EVENITY": 9.020705761638062, "EVISTA": 6.86047238571675, "EXFORGE": 3.923154031353697, "FORSTEO": 10.303883257081171, "HEPSERA": 18.285661805768235, "HUMALOG": 1.7433243450855829, "LANTUS": 1.6874420448278136, "SIMPONI": 1.3559444544220731, "SPINRAZA": 13.395104867026284, "STELARA": 1.0793756259543137, "STRIBILD": 10.712464721935309, "SUBOXONE": 3.257640761404787, "TRUVADA": 16.57487096589126, "VIREAD": 6.192673703728704, "XELJANZ": 2.723282264684895, "null": 0.6019921250843516}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11726.json
new file mode 100644
index 00000000000..fe9fb53e246
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11726.json
@@ -0,0 +1 @@
+{"LANTUS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11727.json
new file mode 100644
index 00000000000..b49973be1eb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11727.json
@@ -0,0 +1 @@
+{"null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11728.json
new file mode 100644
index 00000000000..020337d4946
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11728.json
@@ -0,0 +1 @@
+{"ABILIFY": 6.4323536560976216, "BRINTELLIX": 6.387545678153426, "COMIRNATY": 0.5146940192212088, "CYMBALTA": 1.992068969184718, "GARDASIL": 6.941868560183478, "KAFTRIO": 6.3896159072256005, "KEPPRA": 2.4798927576543326, "LATUDA": 6.425829670251649, "OLANZAPINE": 1.2704315525769014, "SPIKEVAX": 0.2012190325179015, "TOZINAMERAN": 0.6030084775651532, "VAXZEVRIA": 0.1918114073550474, "ZYPREXA": 1.8286863075062307, "null": 3.3653158118719086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11729.json
new file mode 100644
index 00000000000..7af70289404
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11729.json
@@ -0,0 +1 @@
+{"NIRAPARIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1173.json
index 0539355ea40..443be6c2385 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1173.json
@@ -1 +1 @@
-{"ARAVA": 3.166956466825836, "COMIRNATY": 1.000877600236124, "PLAVIX": 4.297140245820985, "TOZINAMERAN": 1.3749743162744723}
\ No newline at end of file
+{"COMIRNATY": 2.1362520709989847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11730.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11730.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11731.json
new file mode 100644
index 00000000000..edd654733e7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11731.json
@@ -0,0 +1 @@
+{"BRIDION": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11732.json
new file mode 100644
index 00000000000..3d10e40cbce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11732.json
@@ -0,0 +1 @@
+{"null": 1.006633644640497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11733.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11733.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11734.json
new file mode 100644
index 00000000000..0e444660c7e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11734.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4311992001941845, "null": 1.069904751617548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11735.json
new file mode 100644
index 00000000000..27137462bd5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11735.json
@@ -0,0 +1 @@
+{"null": 0.5899625428937079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11736.json
new file mode 100644
index 00000000000..3f92d4df5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11736.json
@@ -0,0 +1 @@
+{"null": 1.174316626625736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11737.json
new file mode 100644
index 00000000000..3b4d1346717
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11737.json
@@ -0,0 +1 @@
+{"APIDRA": 28.1183835003678, "DELAMANID": 111.79143234276958, "null": 0.7869577122163464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11738.json
new file mode 100644
index 00000000000..99d027a50b9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11738.json
@@ -0,0 +1 @@
+{"APIDRA": 16.42877489697499, "BIKTARVY": 56.24260744027168, "COMIRNATY": 0.1405278027110362, "COSENTYX": 21.981137076329155, "ZOSTAVAX": 4.603932822554935, "ZYPREXA": 6.813225132136809, "null": 0.5657321966071467}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11739.json
new file mode 100644
index 00000000000..517275a84c2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11739.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5015509343836992, "STELARA": 13.000880845114123, "null": 0.3394429550872333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1174.json
index eb3aafdad82..3761355c1c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1174.json
@@ -1 +1 @@
-{"null": 6.8031563798956105}
\ No newline at end of file
+{"COMIRNATY": 4.794032710695114, "MODERNA": 2.0692154251853023, "SPIKEVAX": 3.716606852044058, "TOZINAMERAN": 6.892638116911817, "VAXZEVRIA": 0.5524922045193968, "null": 0.0615024399311319}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11740.json
new file mode 100644
index 00000000000..2bb0bb7f041
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11740.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.1215422485928173, "ADALIMUMAB": 0.1438531826232391, "ADENURIC": 0.9368168998626208, "AERIUS": 0.5250766751288347, "AFINITOR": 0.0800759605616694, "AIMOVIG": 2.24261256432603, "AJOVY": 5.472886395338049, "ALDARA": 0.7352767396656982, "ALIMTA": 0.2504981362202292, "AMIKACIN": 2.754651579354128, "AMINOSALICYLIC": 0.1485230910216911, "APIDRA": 0.1434400802604103, "APIXABAN": 0.5333127049126961, "APROVEL": 1.89870148398801, "APTIVUS": 3.683780988840986, "ARAVA": 0.0321464557224518, "ATRIPLA": 0.0302045784011531, "AUBAGIO": 0.2195404482300833, "AVAMYS": 0.2773858018628924, "AVASTIN": 0.1158536230065201, "AZATHIOPRINE": 0.599441030774639, "BEDAQUILINE": 0.2665753871176074, "BENLYSTA": 0.1924911302321626, "BETMIGA": 0.4558174937789995, "BIKTARVY": 0.29584129121686, "BRILIQUE": 0.3582051996889741, "BRINTELLIX": 1.7218217240899067, "BUDESONIDE": 0.2091340617291551, "BUMETANIDE": 0.6162783242443012, "BUPIVACAINE": 0.5613899520523907, "BUPRENORPHINE": 0.1609176046902272, "BYDUREON": 1.6943807658650427, "CELLCEPT": 0.150592517820701, "CHAMPIX": 1.0757640677670626, "CIMZIA": 0.0875148425113156, "CLOPIDOGREL": 0.5553323512965062, "COAPROVEL": 2.117037792442201, "COMBIVIR": 0.6805202614384934, "COMIRNATY": 2.444256317016576, "COSENTYX": 0.1799280521371275, "CYMBALTA": 4.129936578264826, "DARZALEX": 0.3004332282230561, "DEXAMETHASONE": 0.2613237964707993, "DULOXETINE": 0.401092843555375, "EFAVIRENZ": 0.5285287791602449, "ELIQUIS": 0.5090520992310265, "EMEND": 0.6117395420503475, "ENBREL": 0.0643983865886918, "ENTRESTO": 0.1807268535704994, "ENTYVIO": 0.1286325618075745, "EXFORGE": 1.901863734809276, "EXJADE": 0.5408717689814655, "FASENRA": 0.4607291524263525, "FASLODEX": 0.3482139940899397, "FENTANYL": 0.1256098799161839, "FORSTEO": 0.3785595855487294, "FORXIGA": 0.4781448160660321, "GALAFOLD": 1.2964794033665794, "GARDASIL": 0.8132807859455536, "HARVONI": 0.4919131718712803, "HIZENTRA": 0.1581182434737283, "HUMALOG": 0.1263838192451043, "HUMIRA": 0.4130810494335646, "HYDROCHLOROTHIAZIDE": 1.307342314078922, "HYDROCORTISONE": 1.858602086919264, "IBRANCE": 0.1014393760375747, "IBUPROFEN": 0.4083474205234431, "INTELENCE": 1.5019489980312375, "IRBESARTAN": 1.045236705343875, "ISENTRESS": 0.5090675255541274, "JAKAVI": 0.2116575136911264, "JANUMET": 0.1750321164294068, "JANUVIA": 0.1573435302883509, "JARDIANCE": 0.0772415134927928, "JCOVDEN": 1.82246658051276, "KAFTRIO": 1.5212145575703837, "KEPPRA": 0.2120213184539593, "KEYTRUDA": 0.0412889497990928, "LANTUS": 0.050905034668773, "LEFLUNOMIDE": 0.3427255426315069, "LEVEMIR": 0.1288182545916769, "LEVETIRACETAM": 0.1359349500416445, "LEVOFLOXACIN": 0.5602893697922613, "LIXIANA": 0.4699601259652795, "LYRICA": 0.5605808056086796, "MEKINIST": 0.1143227759878386, "MELATONIN": 0.4391325296567377, "MEPOLIZUMAB": 0.2946497007084526, "METHOTREXATE": 0.1277027082675238, "MICARDIS": 1.1395555232887262, "MMRVAXPRO": 0.0615030722673207, "MODERNA": 3.143353513750849, "NEXAVAR": 0.1200884336923065, "NIMENRIX": 0.2805071743995125, "NUCALA": 0.1142336539445086, "OCRELIZUMAB": 2.042442965573819, "OLANZAPINE": 0.1936487069164313, "OPSUMIT": 0.0882237717764349, "PEGASYS": 0.9768941062524956, "PEGINTERFERON": 0.4355795047332493, "PEGINTRON": 0.7075083502266106, "PLAVIX": 0.289590525487838, "RANEXA": 3.5800039582897085, "RANOLAZINE": 0.938255852523562, "RASILEZ": 0.6845068388027411, "REBETOL": 0.7795796670559579, "REVATIO": 0.245797986411664, "RINVOQ": 0.6139885977379416, "RITUXIMAB": 0.1237987339079217, "ROACTEMRA": 0.2893889207647244, "SAXENDA": 0.4522330279024998, "SHINGRIX": 0.583538295897959, "SIFROL": 0.6882317516225669, "SILDENAFIL": 0.995300072280518, "SIMPONI": 0.2634974063024193, "SOLIRIS": 0.1152971434780785, "SOVALDI": 0.3193076589564297, "SPIKEVAX": 2.060643594255768, "SPINRAZA": 0.3402179674697356, "SPRYCEL": 0.3021396847937636, "STELARA": 0.4537797751082712, "SUBOXONE": 0.1566933454578849, "SUTENT": 0.0756207054479153, "TAMIFLU": 0.3235954597823914, "TASIGNA": 0.1908896615974067, "TELMISARTAN": 1.1914948101668212, "TIGECYCLINE": 3.800741086353969, "TOBRAMYCIN": 3.927624229707052, "TOZINAMERAN": 2.8561861639942334, "TRULICITY": 0.2588483115531601, "TRUVADA": 0.0517868857932189, "TWINRIX": 1.0382394861494724, "VAXZEVRIA": 1.876867827206812, "VFEND": 0.3153895036438618, "VIAGRA": 1.6611821614277065, "VIMPAT": 1.1626164690826957, "VOTRIENT": 0.098158312457466, "XELJANZ": 0.3040289688216687, "XOLAIR": 0.2374821776966417, "XTANDI": 0.2489694096857401, "XYREM": 0.4618775155244811, "ZOSTAVAX": 0.7426351645506837, "ZYPREXA": 0.2447805784298496, "null": 0.6949737038919778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11741.json
new file mode 100644
index 00000000000..c85507097ce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11741.json
@@ -0,0 +1 @@
+{"null": 0.5656452957169851}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11742.json
new file mode 100644
index 00000000000..1bde3c58548
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11742.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.400707636312768, "VAXZEVRIA": 0.946502703100736, "null": 1.4468388364621074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11743.json
new file mode 100644
index 00000000000..cd57cca0d5f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11743.json
@@ -0,0 +1 @@
+{"FORSTEO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11744.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11744.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11745.json
new file mode 100644
index 00000000000..17866a8b763
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11745.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": 15.363916015607268, "null": 2.750298881818667}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11746.json
new file mode 100644
index 00000000000..b5544f89528
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11746.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 112.25694605794094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11747.json
new file mode 100644
index 00000000000..72fd18a15b1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11747.json
@@ -0,0 +1 @@
+{"null": 8.441874263169586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11748.json
new file mode 100644
index 00000000000..03782a7a125
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11748.json
@@ -0,0 +1 @@
+{"CHAMPIX": 122.80309758044258, "null": 2.3256608919373445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11749.json
new file mode 100644
index 00000000000..f9f3e8e6342
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11749.json
@@ -0,0 +1 @@
+{"CHAMPIX": 373.64173975128256, "null": 0.502266951638484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1175.json
index b90869de669..9fdc9ec2ca1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1175.json
@@ -1 +1 @@
-{"COVID19": 2.248405392731321, "ELIQUIS": 3.396716618375932, "TOZINAMERAN": 3.6437677663766967, "null": 1.1317912716697731}
\ No newline at end of file
+{"COMIRNATY": 7.463245206185721, "COSENTYX": 0.3611821530422395, "GARDASIL": 0.1503974427089141, "IBRANCE": 0.08381301380344, "MMRVAXPRO": 0.1925171176713864, "MODERNA": 5.923419121732695, "NIMENRIX": 1.9583965863177084, "OCRELIZUMAB": 0.8063830716089755, "SHINGRIX": 0.7863030077377158, "SPIKEVAX": 4.544652974091021, "STELARA": 0.1238868334631924, "TOZINAMERAN": 5.697151655923116, "VAXZEVRIA": 0.7096523533653246, "null": 0.0271885455529678}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11750.json
new file mode 100644
index 00000000000..482419307db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11750.json
@@ -0,0 +1 @@
+{"APIDRA": 7.770620426632562, "AVANDIA": 2.205213782983147, "COMIRNATY": 0.0460362044069118, "EMPAGLIFLOZIN": 26.86507434808359, "ENBREL": 2.6764428343948503, "FORXIGA": 23.930535023438445, "HUMALOG": 7.326732968451391, "INSULIN": 5.352584193383767, "INVOKANA": 504.1782489129577, "JANUMET": 4.370695834824109, "JANUVIA": 3.50881997514175, "JARDIANCE": 36.54694759618695, "LANTUS": 22.55587039316186, "LEVEMIR": 19.542138285371063, "STRIBILD": 2.4233715198134385, "VELTASSA": 22.579026283911684, "null": 0.3756057904220622}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11751.json
new file mode 100644
index 00000000000..aa77551242d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11751.json
@@ -0,0 +1 @@
+{"SIMPONI": 22.79091043231759, "null": 0.3968736970429183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11752.json
new file mode 100644
index 00000000000..4f85cd73410
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11752.json
@@ -0,0 +1 @@
+{"null": 4.269597741710298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11753.json
new file mode 100644
index 00000000000..a246d919871
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11753.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.6486764575840065}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11754.json
new file mode 100644
index 00000000000..f0401afe8dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11754.json
@@ -0,0 +1 @@
+{"null": 0.5234282361212452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11755.json
new file mode 100644
index 00000000000..69ba487b2c7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11755.json
@@ -0,0 +1 @@
+{"RANEXA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11756.json
new file mode 100644
index 00000000000..5f68282464f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11756.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3308056575863083, "CYMBALTA": 2.0722622589501536, "GARDASIL": 3.2083603613432325, "KEPPRA": 6.866616479289865, "LANTUS": 1.6031958864156437, "OLANZAPINE": 3.296366134969724, "SPIKEVAX": 0.3005061994641873, "TOZINAMERAN": 0.772606800111207, "VAXZEVRIA": 0.1570146684420766, "null": 2.5647704210641358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11757.json
new file mode 100644
index 00000000000..b2cb36ff72a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11757.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7261520606477972, "IBRANCE": 2.3185653266195647, "NEXAVAR": 2.9083840566205024, "PEGASYS": 1.136508866430452, "SPIKEVAX": 0.6492841146267435, "SUTENT": 6.136298379241493, "TOZINAMERAN": 0.9083500784454996, "TRELEGY": 5.706501766230998, "VAXZEVRIA": 0.6009431079979806, "null": 1.372113684630679}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11758.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11758.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11759.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11759.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1176.json
index f3bb649bf21..c395af168e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1176.json
@@ -1 +1 @@
-{"LATUDA": 30.981787930057248, "OLANZAPINE": 16.254253827353367, "null": 2.9558649782108204}
\ No newline at end of file
+{"COMIRNATY": 1.235512627321565, "VAXZEVRIA": 0.7922316571174038, "null": 0.3017355639313818}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11760.json
new file mode 100644
index 00000000000..36d88fd6c56
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11760.json
@@ -0,0 +1 @@
+{"CHAMPIX": 3.4152138190619423, "COMIRNATY": 0.6660433148481004, "COSENTYX": 1.6016679882736693, "FORSTEO": 2.8366328577809226, "PEGASYS": 1.0163291204201914, "SPIKEVAX": 0.5091199453402655, "TOZINAMERAN": 0.7851133620982408, "TRELEGY": 5.26185077474976, "VAXZEVRIA": 0.534085673688769, "null": 2.1260394229720743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11761.json
new file mode 100644
index 00000000000..3f81eaebd5d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11761.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1487764163955794, "PEGASYS": 1.7431831276500878, "PEGINTRON": 1.4795649087154292, "SPIKEVAX": 0.1335971273181177, "SUTENT": 1.8899953238088256, "TOZINAMERAN": 0.2429660051068372, "VAXZEVRIA": 0.220951786689967, "null": 5.387539065962389}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11762.json
new file mode 100644
index 00000000000..9dbc7d2fd9c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11762.json
@@ -0,0 +1 @@
+{"AFINITOR": 1.1061694468521623, "CHAMPIX": 0.6654224205239452, "CLOPIDOGREL": 0.6181465933186565, "COMIRNATY": 0.9316507966222538, "COSENTYX": 1.0175153324498272, "EFAVIRENZ": 5.459728999310282, "ELIQUIS": 0.4108976825333402, "ENTRESTO": 1.1219055877060895, "FORSTEO": 1.5293888110265892, "INLYTA": 2.858204674806904, "LANTUS": 0.3844364112574039, "NEXAVAR": 1.0815867245796933, "PEGASYS": 0.7786394052319531, "PEGINTRON": 0.6971987452173845, "SHINGRIX": 0.9012308164188446, "SPIKEVAX": 0.4724992920804973, "SUBOXONE": 0.820642962977502, "SUTENT": 7.150829389691351, "TOZINAMERAN": 0.7714290504873149, "TRELEGY": 1.4761137050540216, "VAXZEVRIA": 0.4607498544456165, "VOTRIENT": 2.6302390230282424, "null": 2.536776399414142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11763.json
new file mode 100644
index 00000000000..70db1b8fc81
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11763.json
@@ -0,0 +1 @@
+{"ABATACEPT": 1.0415554967302798, "ADALIMUMAB": 1.0841420492600196, "AFINITOR": 1.2678911902478316, "CHAMPIX": 1.6151393054244985, "CICLOSPORIN": 0.9134202412763884, "COMIRNATY": 0.3967457833084464, "IBRANCE": 2.721550343365679, "INLYTA": 4.118691375170656, "LEVETIRACETAM": 2.2281372618864235, "NEXAVAR": 0.9252842475832812, "OLANZAPINE": 0.973750733285234, "PEGASYS": 2.371113596964113, "PEGINTRON": 2.5842445354635366, "SPIKEVAX": 0.2119826229964844, "SUTENT": 6.277673621277647, "TOZINAMERAN": 1.5944756756656913, "VAXZEVRIA": 0.2410681313599067, "XELJANZ": 1.1286605590766374, "XOLAIR": 2.40085035171356, "ZYPREXA": 1.2837152816997954, "null": 1.8940775365916136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11764.json
new file mode 100644
index 00000000000..ada2a42b3f7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11764.json
@@ -0,0 +1 @@
+{"CHAMPIX": 3.245085857609662, "COMIRNATY": 0.621247067858761, "SPIKEVAX": 0.4771113619601053, "SUTENT": 4.057836595398968, "TOZINAMERAN": 1.3860105942319243, "VAXZEVRIA": 0.5565661958548589, "null": 1.543350313286165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11765.json
new file mode 100644
index 00000000000..dad9751dce4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11765.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9995157560613604, "SPIKEVAX": 0.4341003858256307, "VAXZEVRIA": 0.6599247826716765, "null": 1.8348105054248764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11766.json
new file mode 100644
index 00000000000..a667af2852e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11766.json
@@ -0,0 +1 @@
+{"CHAMPIX": 2.6545457502267094, "COMIRNATY": 0.4438046054757135, "FORSTEO": 2.8831152868919405, "PEGASYS": 2.197327208547188, "SPIKEVAX": 0.3052754995511679, "SUTENT": 6.330261428804369, "TOZINAMERAN": 0.3679532909746518, "VAXZEVRIA": 0.1863203236486148, "null": 2.508091672407168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11767.json
new file mode 100644
index 00000000000..6a298d4b3e7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11767.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2563412099537487, "SUTENT": 6.761081729828359, "null": 1.3451248718349684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11768.json
new file mode 100644
index 00000000000..4448fc8ed31
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11768.json
@@ -0,0 +1 @@
+{"null": 1.0358882398694322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11769.json
new file mode 100644
index 00000000000..8823bd51c06
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11769.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9368396068599943, "null": 0.6628283308677327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1177.json
index 1e2476099d8..64586769809 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1177.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 28.42816700901442, "null": 2.187165700215114}
\ No newline at end of file
+{"COMIRNATY": 2.515307204370868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11770.json
new file mode 100644
index 00000000000..61009c446bc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11770.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2486924415438756, "null": 1.943952121891223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11771.json
new file mode 100644
index 00000000000..c27cb4947ee
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11771.json
@@ -0,0 +1 @@
+{"BRILIQUE": 15.552684468927318, "CLOPIDOGREL": 11.209952261553411, "COMIRNATY": 0.1416903619817892, "ELIQUIS": 3.755364569303107, "PLAVIX": 7.9966166452974194, "SUTENT": 1.8716588772847944, "VAXZEVRIA": 0.1704279054891928, "null": 1.785187994848064}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11772.json
new file mode 100644
index 00000000000..a5f53a5cc74
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11772.json
@@ -0,0 +1 @@
+{"KEPPRA": 5.631460989953521, "SPIKEVAX": 0.2638727280631995, "SUTENT": 11.859503207379664, "null": 1.400068739332979}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11773.json
new file mode 100644
index 00000000000..74374d2cf52
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11773.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4080348821055509, "LATUDA": 25.67288451600384, "SPIKEVAX": 0.2578631091290322, "TOZINAMERAN": 1.1901664613607406, "VAXZEVRIA": 0.2379001917520321, "null": 2.3057219667252045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11774.json
new file mode 100644
index 00000000000..7aa318812a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11774.json
@@ -0,0 +1 @@
+{"null": 0.9505518610027304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11775.json
new file mode 100644
index 00000000000..cc849d850a8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11775.json
@@ -0,0 +1 @@
+{"null": 1.3096339481926855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11776.json
new file mode 100644
index 00000000000..4ab9fc23299
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11776.json
@@ -0,0 +1 @@
+{"ELIQUIS": 2.583606410798398, "RINVOQ": 13.650786008308922, "STELARA": 6.613194707837242, "null": 1.1389389456999952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11777.json
new file mode 100644
index 00000000000..ab3fdde2804
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11777.json
@@ -0,0 +1 @@
+{"AFINITOR": 2.028167211359427, "APROVEL": 2.743003058774251, "BRIDION": 3.003541560232772, "BRILIQUE": 1.8686049987979343, "CHAMPIX": 0.3391373384127819, "CLOPIDOGREL": 0.5299775744849513, "COAPROVEL": 4.34366575620832, "COMIRNATY": 0.6312530127782321, "ELIQUIS": 0.2652880749907739, "ENTRESTO": 1.3159940904580112, "EXFORGE": 1.3054766542640357, "FENTANYL": 0.5122927209421491, "IBUPROFEN": 2.665107685107109, "LEVOFLOXACIN": 1.6984475006282456, "MIDAZOLAM": 1.541036413862486, "MODERNA": 0.6219859603789156, "OMALIZUMAB": 1.483153943399349, "PLAVIX": 0.3119123714572189, "RASILEZ": 3.5821056342397206, "ROACTEMRA": 1.8405036262996015, "SPIKEVAX": 0.1903816342308782, "SUTENT": 0.1458147215255298, "SYCREST": 10.430493009811324, "TOZINAMERAN": 0.2223565689832808, "VAXZEVRIA": 0.2578344729264203, "XOLAIR": 1.5499523326470952, "null": 5.376500424921247}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11778.json
new file mode 100644
index 00000000000..1ce9babaa84
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11778.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9134254667908368, "SPIKEVAX": 1.0637686344170802, "TOZINAMERAN": 1.0261034318668727, "VAXZEVRIA": 0.2306692124952449, "null": 1.4291473600837834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11779.json
new file mode 100644
index 00000000000..26ee34bfad8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11779.json
@@ -0,0 +1 @@
+{"null": 0.6192836920493578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1178.json
index 246b25d2e0b..48cd04b08d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1178.json
@@ -1 +1 @@
-{"null": 2.05052867485809}
\ No newline at end of file
+{"COMIRNATY": 0.2764730755060544, "CYTARABINE": 14.49784258602676, "null": 1.2490546061006855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11780.json
new file mode 100644
index 00000000000..f295e94e428
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11780.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.6624753601484277, "SPIKEVAX": 0.381760723171433, "TOZINAMERAN": 1.9940450179876823, "VAXZEVRIA": 0.3068595549927293, "null": 2.445004774202056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11781.json
new file mode 100644
index 00000000000..86ca637e9fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11781.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8741801849889643, "SUTENT": 5.148860036055853, "null": 1.9134096328624648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11782.json
new file mode 100644
index 00000000000..4c29866c596
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11782.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7048447366327104, "null": 1.3451248718349684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11783.json
new file mode 100644
index 00000000000..36284c8de24
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11783.json
@@ -0,0 +1 @@
+{"AFINITOR": 3.830768564606766, "ARAVA": 0.8553576090744107, "CICLOSPORIN": 5.556874678845571, "COMIRNATY": 0.36615808701341, "COSENTYX": 1.8436341489105932, "DOCETAXEL": 6.125723691725801, "IBRANCE": 1.5774481712219028, "NEXAVAR": 3.669896184241869, "PEGASYS": 1.1702506408295468, "PEGINTRON": 3.4065075693555658, "SPIKEVAX": 0.2492695024314543, "SUTENT": 2.403934796334707, "TOZINAMERAN": 1.0965682156140262, "VAXZEVRIA": 0.3863170573122201, "XELJANZ": 1.154918776700197, "null": 1.4174959960455322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11784.json
new file mode 100644
index 00000000000..914585f151f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11784.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4324989266173077, "DEXAMETHASONE": 5.184627436356228, "GARDASIL": 27.801345092527264, "MENVEO": 18.47153807110239, "MMRVAXPRO": 2.942719119286678, "NIMENRIX": 10.97674843661849, "SPIKEVAX": 0.242041452513882, "TOZINAMERAN": 0.5818844311186115, "VAXZEVRIA": 0.13661541527834, "null": 2.076641151964732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11785.json
new file mode 100644
index 00000000000..2b025f76795
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11785.json
@@ -0,0 +1 @@
+{"BRIVIACT": 25.358977684173944, "CICLOSPORIN": 1.0968518779652203, "COMIRNATY": 0.3140003339350191, "GARDASIL": 3.0766820110088275, "KEPPRA": 9.582088944957915, "LACOSAMIDE": 27.920142904707436, "LEVETIRACETAM": 33.059397324019265, "MIDAZOLAM": 6.4241454497223245, "MMRVAXPRO": 2.3288767526889287, "OLANZAPINE": 2.7114853524279945, "SPIKEVAX": 0.1918769192240755, "TOZINAMERAN": 0.920873659254536, "VAXZEVRIA": 0.3046192861641856, "ZONISAMIDE": 106.94908801847065, "null": 2.1633852427223133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11786.json
new file mode 100644
index 00000000000..a96a50dd56c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11786.json
@@ -0,0 +1 @@
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11787.json
new file mode 100644
index 00000000000..63dc9559a3f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11787.json
@@ -0,0 +1 @@
+{"METFORMIN": 142.19237395618146, "PANTOPRAZOLE": 40.722139663883546, "null": 0.5992409017621542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11788.json
new file mode 100644
index 00000000000..97c98e59c73
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11788.json
@@ -0,0 +1 @@
+{"ARAVA": 2.3126316543365864, "COMIRNATY": 0.2357427525922394, "DOCETAXEL": 36.66135298200761, "SOMATROPIN": 271.355272624483, "null": 1.236058781425703}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11789.json
new file mode 100644
index 00000000000..bbaf488b12a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11789.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8287283802232102, "null": 0.466733711871285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1179.json
index 5c5ccb154e7..5f41e0d4dbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1179.json
@@ -1 +1 @@
-{"ABATACEPT": 23.44327185612402, "ADALIMUMAB": 44.041831875841744, "ANAKINRA": 281.1872421712064}
\ No newline at end of file
+{"null": 4.267042736566179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11790.json
new file mode 100644
index 00000000000..ad29bd2e736
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11790.json
@@ -0,0 +1 @@
+{"null": 0.4626169507637018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11791.json
new file mode 100644
index 00000000000..084e30d2daf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11791.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.818015780763003, "GARDASIL": 1.245677849720311, "MMRVAXPRO": 3.825523691449448, "SPIKEVAX": 0.98749032094735, "TOZINAMERAN": 2.7545869053763066, "VAXZEVRIA": 1.010133401671706, "null": 0.9817206543904018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11792.json
new file mode 100644
index 00000000000..67c60e361bb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11792.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.136662543351806, "SPIKEVAX": 1.1197654159105173, "VAXZEVRIA": 0.3510357696338781, "null": 0.6095413014890066}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11793.json
new file mode 100644
index 00000000000..c1bbb4b698c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11793.json
@@ -0,0 +1 @@
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11794.json
new file mode 100644
index 00000000000..2ca5572d3b1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11794.json
@@ -0,0 +1 @@
+{"COSENTYX": 77.82964788506435}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11795.json
new file mode 100644
index 00000000000..f0f988a1128
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11795.json
@@ -0,0 +1 @@
+{"GARDASIL": 4.62571182282145, "JANUMET": 15.167026945150411, "JANUVIA": 40.74743326665609, "NAGLAZYME": 53.80221331505649, "ZOSTAVAX": 10.462514456309403, "null": 1.2094644590482997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11796.json
new file mode 100644
index 00000000000..4aef9572896
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11796.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 0.9421740068291466, "CIMZIA": 0.9421192800978816, "COMIRNATY": 1.0233586693732184, "COSENTYX": 9.478337018363916, "ENTYVIO": 3.722835766120965, "GARDASIL": 3.8434976311010542, "IBUPROFEN": 1.5074035645933246, "KEPPRA": 0.544462510840552, "MMRVAXPRO": 5.315952342238215, "MODERNA": 1.0311408814249114, "NIMENRIX": 3.293398690562231, "PEGASYS": 0.4853264532507004, "PLAVIX": 0.585557163699982, "RINVOQ": 3.535301996118612, "ROACTEMRA": 2.9881675084516326, "SIMPONI": 12.516488808160586, "SOLIRIS": 1.2517769095359526, "SPIKEVAX": 0.6286206861937105, "STELARA": 3.2264091977766576, "SUTENT": 0.2737398833350098, "SYNAGIS": 4.117114807066312, "SYNFLORIX": 50.87302756135354, "TOZINAMERAN": 1.50885631959488, "VAXZEVRIA": 0.4572247244529573, "VFEND": 1.8192691713119156, "XELJANZ": 0.7405504455385314, "XOLAIR": 1.194491534379206, "null": 1.043155676525401}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11797.json
new file mode 100644
index 00000000000..c0be6e237c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11797.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5199017270662963, "null": 0.7312094378012679}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11798.json
new file mode 100644
index 00000000000..db9fc391e70
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11798.json
@@ -0,0 +1 @@
+{"null": 0.998193471464212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11799.json
new file mode 100644
index 00000000000..7def47ab365
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11799.json
@@ -0,0 +1 @@
+{"AFINITOR": 2.5025125209038177, "ARAVA": 0.8725393525705171, "ATRIPLA": 0.5837587657763575, "AUBAGIO": 4.919765794857764, "BENLYSTA": 4.632286961005069, "CIMZIA": 2.564115732163432, "COMIRNATY": 0.1141348325375014, "COSENTYX": 9.122525205964068, "ELIQUIS": 1.6372727362091273, "ENBREL": 4.101836350581312, "ENTYVIO": 2.258989895423206, "FORSTEO": 2.900563769782061, "HIZENTRA": 6.933241907253326, "HUMIRA": 7.841078157166755, "IBRANCE": 2.502978727528156, "METHOTREXATE": 8.722116733686994, "PEGASYS": 2.544499742450005, "PEGINTRON": 2.4929345199523385, "RINVOQ": 2.8278876827907213, "RITUXIMAB": 2.462726908606096, "ROACTEMRA": 4.367795401569158, "SIMPONI": 14.52092566594615, "SPIKEVAX": 0.0667677757601443, "STELARA": 8.439770888180863, "SUTENT": 2.9434452501318784, "TOZINAMERAN": 0.2637376216311264, "VAXZEVRIA": 0.1040901834887308, "VOTRIENT": 1.7238177274079536, "XELJANZ": 12.171259304821907, "XTANDI": 1.3160531048667246, "ZOSTAVAX": 1.256885239684578, "null": 0.5914918064611687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/118.json
index b588c6bbfd5..5f4cbe8c3d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/118.json
@@ -1 +1 @@
-{"EMTRICITABINE": 193.12131468787092, "TRUVADA": 280.20277738887563}
\ No newline at end of file
+{"null": 0.4221857971457376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1180.json
index 353ab04c7af..d3ebbad5143 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1180.json
@@ -1 +1 @@
-{"APIXABAN": 2.2767805034840185, "BUDESONIDE": 2.1800557778595326, "BYDUREON": 15.00285044536366, "BYETTA": 5.856380915118072, "CELLCEPT": 1.7496434279962476, "CYMBALTA": 2.384255670907794, "ELIQUIS": 5.262931215666815, "ENBREL": 1.8742653868453365, "EVISTA": 49.31886112704123, "FASENRA": 3.040878250516859, "FASLODEX": 12.636934433116048, "FORSTEO": 1.831208111858439, "FULVESTRANT": 4.470140625322871, "HUMALOG": 1.9539496287221232, "IBRANCE": 5.219871967464576, "LYRICA": 6.772166780721491, "PLAVIX": 1.7100901693788118, "RAPAMUNE": 6.121524703993062, "REVATIO": 16.474720539062048, "SIMPONI": 2.603707816295383, "SUTENT": 1.5755698171453616, "TAGRISSO": 4.185769001700461, "TOVIAZ": 17.66579520163965, "VIAGRA": 3.0738442587627364, "XELJANZ": 4.109398001371105, "null": 2.3283573946524942}
\ No newline at end of file
+{"ARANESP": 4.719187238385426, "ATRIPLA": 0.4560018613134226, "AVANDIA": 1.8318437260651808, "CELLCEPT": 3.272608827504853, "CICLOSPORIN": 6.211421267112526, "COMIRNATY": 0.0367117346237777, "ENTRESTO": 3.160396016433929, "EXJADE": 3.514590358387216, "FORSTEO": 1.9858586624500485, "LEVOFLOXACIN": 2.000708110844585, "PEGINTRON": 2.006257349114239, "SOLIRIS": 2.5298864992063663, "SUTENT": 1.6230713529600969, "TRUVADA": 0.6613663388848451, "VIREAD": 6.17060581069334, "VOTRIENT": 2.1059066794008943, "null": 1.982209799196312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11800.json
new file mode 100644
index 00000000000..d9040f613b6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11800.json
@@ -0,0 +1 @@
+{"null": 2.8764739912114345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11801.json
new file mode 100644
index 00000000000..3564363080e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11801.json
@@ -0,0 +1 @@
+{"CORTICOSTEROID": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11802.json
new file mode 100644
index 00000000000..7545015a058
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11802.json
@@ -0,0 +1 @@
+{"PROTELOS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11803.json
new file mode 100644
index 00000000000..24241a6843e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11803.json
@@ -0,0 +1 @@
+{"null": 1.4853773445371572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11804.json
new file mode 100644
index 00000000000..acec39794b1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11804.json
@@ -0,0 +1 @@
+{"null": 1.6194022590602462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11805.json
new file mode 100644
index 00000000000..45f2a1d7493
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11805.json
@@ -0,0 +1 @@
+{"AVAMYS": 70.67433554606883, "null": 0.5417393194743858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11806.json
new file mode 100644
index 00000000000..e48c1dcf247
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11806.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.3855533678579155, "COMIRNATY": 0.0206965147017186, "FORSTEO": 2.492577333048867, "KEPPRA": 1.546040894851893, "SUTENT": 1.0254750321145023, "SYCREST": 24.008684659261984, "VAXZEVRIA": 0.0819788640123328, "null": 10.28292793239619}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11807.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11807.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11808.json
new file mode 100644
index 00000000000..d6477e1c35d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11808.json
@@ -0,0 +1 @@
+{"ABATACEPT": 1.0765633618953525, "AFINITOR": 0.6884905801256507, "AIMOVIG": 1.3395471134679788, "ANAKINRA": 4.621005184961777, "ARAVA": 3.6831375621738327, "ASPARAGINASE": 1.7330151324498682, "ATRIPLA": 2.7618043109523787, "AUBAGIO": 1.6975370647290116, "AZATHIOPRINE": 6.583499153821766, "BENLYSTA": 1.1389478600214846, "BONVIVA": 6.1082105189143565, "BUDESONIDE": 0.7414675723624364, "BUPRENORPHINE": 2.26966948617384, "CABOMETYX": 3.4526729042316786, "COMIRNATY": 0.0770825727171103, "COSENTYX": 1.267187518942534, "CYMBALTA": 1.1538901596523128, "ELIQUIS": 19.478541744647742, "ENBREL": 1.8953683992914512, "EVENITY": 6.273600837694171, "EVISTA": 3.3620690707780847, "EXFORGE": 1.5317848595429495, "FASLODEX": 2.627146396646338, "FORSTEO": 2.924460618253312, "HUMALOG": 0.6962068037812864, "IBRANCE": 4.4198639745993145, "INLYTA": 1.666195572692051, "JANUVIA": 1.9180574007002105, "KALETRA": 2.513021536119316, "KEPPRA": 2.2521544722315485, "KEYTRUDA": 0.6322854991659071, "LANTUS": 0.8293006303653571, "LEVOFLOXACIN": 0.7003498322027266, "LYRICA": 1.4818857839205388, "METHOTREXATE": 1.8559881585221, "OCRELIZUMAB": 2.2194948584385994, "OFEV": 1.8129997968262872, "OLANZAPINE": 0.4726641777688935, "PEGASYS": 1.2054183769694264, "PEGINTRON": 0.940895985718719, "PLAVIX": 0.5644405670467691, "PREGABALIN": 4.288005965287804, "RITUXIMAB": 2.51177965121084, "ROACTEMRA": 2.7615068310334365, "SIMPONI": 1.8535180267498503, "SPIKEVAX": 0.0347619517315975, "SPRYCEL": 1.8494892783226469, "STELARA": 1.129995446487082, "STRIBILD": 3.680807680656984, "SUBOXONE": 5.24015540242561, "SUTENT": 4.390206126690364, "TOVIAZ": 1.858822201966838, "TOZINAMERAN": 0.112678628557842, "TRUVADA": 1.3343356222498135, "VAXZEVRIA": 0.0197394991734466, "VIAGRA": 1.9443820739222244, "XELJANZ": 2.827244182047453, "XTANDI": 0.7907039641824323, "XYREM": 5.840999857338879, "ZOMETA": 10.949681459368056, "ZOSTAVAX": 0.8346209111467546, "ZYPREXA": 0.5114635097710151, "null": 0.8499427580287957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11809.json
new file mode 100644
index 00000000000..1cf31b69de1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11809.json
@@ -0,0 +1 @@
+{"ATRIPLA": 2.060872844639641, "SUBOXONE": 14.66997546059472, "null": 2.502192345034316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1181.json
index 6e93f4133a5..0380f762297 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1181.json
@@ -1 +1 @@
-{"null": 1.1646108727749316}
\ No newline at end of file
+{"BLINCYTO": 776.1144927464509, "CYTARABINE": 57.5122810435514, "KYMRIAH": 80.35453078541197, "null": 0.2328680369631671}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11810.json
new file mode 100644
index 00000000000..946e6a9124d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11810.json
@@ -0,0 +1 @@
+{"ARAVA": 0.7075839893831192, "ATRIPLA": 8.557299879449575, "BENLYSTA": 8.31033684750177, "BONVIVA": 51.37317514056999, "CIMZIA": 1.122546298644674, "COMIRNATY": 0.0822587528330848, "ELIQUIS": 4.15589753551496, "EVENITY": 17.492160552502018, "IBRANCE": 6.648855815351578, "MEPOLIZUMAB": 2.3301321007260465, "OPSUMIT": 3.079920817825186, "PEGASYS": 1.6240596644466567, "PEGINTRON": 1.5285484404737666, "SIMPONI": 14.06304086346126, "STELARA": 2.2256186450706803, "STRIBILD": 5.042597811637255, "SUTENT": 0.9450811038585576, "TRUVADA": 4.667684666002426, "XELJANZ": 1.7715960230329748, "XTANDI": 2.065093327589126, "ZOMETA": 91.64366988596448, "ZYPREXA": 1.0531034164513762, "null": 0.6190981812407921}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11811.json
new file mode 100644
index 00000000000..ef9306d6b0a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11811.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.6439544332993188, "ARAVA": 0.7464908541278992, "ATRIPLA": 35.97445322838687, "AUBAGIO": 1.72418840643655, "BENLYSTA": 1.5634079708790831, "BONVIVA": 6.912397091587622, "CIMZIA": 0.5750715791604695, "COMIRNATY": 0.0291110345715208, "COSENTYX": 0.6568100687737665, "CYMBALTA": 0.6179671979740738, "ELIQUIS": 2.1739857829467994, "FORSTEO": 1.61813939306082, "FULVESTRANT": 3.355686490705604, "GARDASIL": 0.7640249933363324, "HUMIRA": 1.492527664762162, "IBRANCE": 2.051255639116788, "KALETRA": 3.08363057788002, "KEPPRA": 1.4430624117210316, "PEGASYS": 0.579754218220641, "PEGINTRON": 0.6480610080108833, "SIMPONI": 1.396119488932891, "SPIKEVAX": 0.0788087631601811, "STELARA": 0.585701619856638, "STRIBILD": 21.65263019670649, "SUBOXONE": 3.708215364821258, "SUTENT": 0.5982158080485779, "TOZINAMERAN": 0.1491028937573273, "TRUVADA": 16.45140878548545, "VIREAD": 8.76327400373845, "XELJANZ": 1.271930186729156, "null": 0.44261763956602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11812.json
new file mode 100644
index 00000000000..5379e9bfdf6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11812.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 110.99681463570089, "null": 1.985668055828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11813.json
new file mode 100644
index 00000000000..ea4a5ae5a8c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11813.json
@@ -0,0 +1 @@
+{"ATRIPLA": 10.067111282495947, "null": 0.4368639307032243}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11814.json
new file mode 100644
index 00000000000..e11545a4a02
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11814.json
@@ -0,0 +1 @@
+{"ABATACEPT": 1.2547895790817931, "AFINITOR": 1.1074027402470832, "ARAVA": 8.292536865519208, "AUBAGIO": 3.067183446428816, "BENLYSTA": 6.479566247594257, "CIMZIA": 2.5017639942967804, "COMIRNATY": 0.1189249034005228, "COSENTYX": 1.5730201027462305, "CYMBALTA": 1.299361210886368, "CYTARABINE": 4.400446714301371, "ELIQUIS": 1.618283157573664, "ENBREL": 1.9436408333149329, "ENTYVIO": 3.041875013652499, "EVENITY": 6.41678709579727, "EXJADE": 1.6860059318495808, "FASLODEX": 4.250484826129025, "FORSTEO": 2.0423670135112846, "HIZENTRA": 4.309896959896177, "HUMIRA": 1.820838691267332, "IBRANCE": 3.63872126070934, "LANTUS": 1.1981595075151503, "METHOTREXATE": 1.261301929379776, "OFEV": 3.696739249755713, "OPSUMIT": 1.5466871760689116, "OZEMPIC": 34.44276667212957, "PEGASYS": 2.2149747826574537, "PEGINTRON": 1.79732031395882, "RITUXIMAB": 5.1333211657057385, "RUCONEST": 14.606423592705545, "SIMPONI": 11.570686992183516, "SPIKEVAX": 0.0459358160465126, "STELARA": 4.496025230104022, "SUTENT": 3.2699464077322715, "TOZINAMERAN": 0.1943492442908058, "VAXZEVRIA": 0.0859400876891365, "XELJANZ": 9.753419617754744, "ZOSTAVAX": 1.8291070790295811, "null": 0.5821229340858706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11815.json
new file mode 100644
index 00000000000..3770c4ce5aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11815.json
@@ -0,0 +1 @@
+{"ATRIPLA": 843.057173709686, "COMIRNATY": 0.0085421806547851, "FORSTEO": 0.1633843554916905, "GARDASIL": 0.1353690533750663, "KEPPRA": 0.2431883174443667, "SPIKEVAX": 0.0103465339045445, "STRIBILD": 0.2098029981312147, "SUBOXONE": 0.2854898572121354, "TOZINAMERAN": 0.0335273362929386, "TRUVADA": 1.697707203229981, "VAXZEVRIA": 0.0071513680650044, "null": 0.0534864527124132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11816.json
new file mode 100644
index 00000000000..de1c7573f61
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11816.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.0892674670092457, "AFINITOR": 0.0892485779687479, "AIMOVIG": 0.0722763265530936, "ARAVA": 0.0134151647006768, "ATRIPLA": 86.98135302347433, "AUBAGIO": 0.1819303403713281, "BIKTARVY": 0.2752204979658562, "BONVIVA": 0.9783557688706388, "BUPRENORPHINE": 1.4506014157402929, "BYDUREON": 0.131413355918633, "COMIRNATY": 0.0088344264359005, "CYMBALTA": 0.104020413425217, "ELIQUIS": 0.0439950694136892, "ENBREL": 0.0880647752912323, "FASLODEX": 0.184306383401697, "FENTANYL": 0.1853803435239337, "FORSTEO": 0.1096437325696199, "FORXIGA": 0.1306516047533454, "GENVOYA": 1.075845529214493, "HARVONI": 0.3790394580631847, "IBRANCE": 0.1697697386564084, "INTRONA": 0.55880815837835, "KALETRA": 4.527200112661415, "KEPPRA": 0.0994172043249109, "LYRICA": 0.1478057907372336, "PEGASYS": 0.2418722887541739, "PEGINTRON": 0.2611278894913861, "PLAVIX": 0.0932319409719986, "RITUXIMAB": 0.3428948578984215, "SIMPONI": 0.1118413148927949, "SPIKEVAX": 0.0033091624873327, "STELARA": 0.0890290926978126, "STRIBILD": 36.9627791881238, "SUBOXONE": 0.9250209106388148, "SUTENT": 0.0933685351119121, "TOZINAMERAN": 0.0112388508239194, "TRUVADA": 42.11848744358908, "VAXZEVRIA": 0.0042588850179825, "VIREAD": 12.845982061748348, "ZYPREXA": 0.0806711640256851, "null": 0.0567624766930587}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11817.json
new file mode 100644
index 00000000000..0c8b574be1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11817.json
@@ -0,0 +1 @@
+{"ROTATEQ": 704.8909425198522, "null": 1.3322555672165173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11818.json
new file mode 100644
index 00000000000..854a231aaba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11818.json
@@ -0,0 +1 @@
+{"null": 0.855331966490197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11819.json
new file mode 100644
index 00000000000..1f8ec2c6826
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11819.json
@@ -0,0 +1 @@
+{"null": 0.8441661466746129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1182.json
index 017ff62ccdf..cb9c29b3d5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1182.json
@@ -1 +1 @@
-{"FORXIGA": 40.55775519864466, "ZOSTAVAX": 238.97932108222813}
\ No newline at end of file
+{"KYMRIAH": 3400.4029704541445, "YESCARTA": 105.01606126652784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11820.json
new file mode 100644
index 00000000000..8c26d59f5e9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11820.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 18.37606446250184, "null": 0.7583904132533784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11821.json
new file mode 100644
index 00000000000..0efe73e8573
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11821.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.6332603054889642, "AFINITOR": 1.0604306834263388, "AIMOVIG": 1.982573996096753, "ANAKINRA": 3.75166986511141, "ATRIPLA": 0.7268363067096913, "AUBAGIO": 2.6215643027396487, "BENLYSTA": 2.083339778994451, "BONVIVA": 6.53543194901932, "CHAMPIX": 1.4659229508440637, "CIMZIA": 0.2263084013411639, "COMIRNATY": 1.346574365157233, "COSENTYX": 1.028839088762843, "CYMBALTA": 1.1684792311572905, "ELIQUIS": 1.1367027622585637, "ENBREL": 2.982791893053795, "ENTYVIO": 1.6578167078859716, "ETANERCEPT": 20.045401273482963, "EXFORGE": 0.9820450705200714, "FAMPYRA": 2.7609608745253147, "FASLODEX": 0.7491514115572676, "FORSTEO": 2.873034675402179, "GARDASIL": 0.5755016467199989, "HUMAN": 2.2829275330481757, "IBRANCE": 2.162361963751906, "IBUPROFEN": 1.4263423154686814, "MODERNA": 0.663326581020528, "OPSUMIT": 0.6826269365679198, "PEGASYS": 0.7491873200880734, "PEGINTRON": 0.5697222005525973, "RINVOQ": 1.3801034196218562, "SHINGRIX": 0.5547015381600011, "SIMPONI": 1.5044993904259742, "SPIKEVAX": 1.3543704138214658, "STELARA": 1.4361554777907344, "SUBOXONE": 2.449941469030418, "SUTENT": 2.2566491094795267, "TOZINAMERAN": 1.6572138585724672, "TREMFYA": 2.5852004981788728, "TRUVADA": 0.244227029936898, "VAXZEVRIA": 1.6634834643925391, "VICTOZA": 1.4302317308791794, "XELJANZ": 1.9683376515319904, "ZOSTAVAX": 0.6778340423482813, "null": 0.6198366331259386}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11822.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11822.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11823.json
new file mode 100644
index 00000000000..f7f5c948e76
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11823.json
@@ -0,0 +1 @@
+{"HYDROCORTISONE": 166.20119662856823, "PROTOPIC": 768.2904198943397, "null": 4.721023000842141}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11824.json
new file mode 100644
index 00000000000..bd3a8702ea1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11824.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.0157314753179925, "ABILIFY": 1.3302892276209657, "ATAZANAVIR": 4.29683847919913, "BENZODIAZEPINES": 36.4015154773553, "BRILIQUE": 1.2176193706968448, "CLOPIDOGREL": 0.5774044341133464, "COMBIVIR": 2.3804226744105392, "COMIRNATY": 0.0080748366650926, "DEXAMETHASONE": 0.9958744569253648, "FENTANYL": 2.133583766827132, "IRBESARTAN": 11.290885564312942, "IVABRADINE": 14.452431858859548, "KEPPRA": 0.6152183592404674, "LEVETIRACETAM": 1.20266677007843, "LEVOFLOXACIN": 10.29237788629443, "MEXILETINE": 60.34591175080017, "MIDAZOLAM": 6.30072403553569, "MULTAQ": 13.64594892288073, "NOXAFIL": 5.670727954872186, "OLANZAPINE": 5.666431919770682, "OSIMERTINIB": 9.240178552416998, "POSACONAZOLE": 16.209239521131057, "PROPRANOLOL": 5.547107213906486, "RANEXA": 12.64698954549783, "RANOLAZINE": 19.51608325145857, "TAGRISSO": 2.3862463935662435, "TAMIFLU": 1.6090269801119383, "VFEND": 6.103977272232234, "VORICONAZOLE": 8.95837744414638, "ZYPREXA": 0.7297787787013682, "null": 6.395126561672951}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11825.json
new file mode 100644
index 00000000000..cd31f954e73
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11825.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 8.54843722316727, "COMIRNATY": 1.1105382037908678, "CYMBALTA": 1.0683417013169072, "FIRDAPSE": 12.4754585950007, "GARDASIL": 1.1377554914819723, "LATUDA": 11.176071403279094, "OLANZAPINE": 11.147504125280523, "SPIKEVAX": 0.7321832505312347, "TOZINAMERAN": 0.2383352185913925, "VAXZEVRIA": 0.4037609125843486, "ZYPREXA": 4.791621878891849, "null": 1.7525612854881}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11826.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11826.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11827.json
new file mode 100644
index 00000000000..a69846ea5de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11827.json
@@ -0,0 +1 @@
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11828.json
new file mode 100644
index 00000000000..6cf6bf77fc7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11828.json
@@ -0,0 +1 @@
+{"null": 1.4737406591636295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11829.json
new file mode 100644
index 00000000000..548df570e36
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11829.json
@@ -0,0 +1 @@
+{"SOLIRIS": 1001.1504906810244}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1183.json
index 0adde54cc07..846ef4d015c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1183.json
@@ -1 +1 @@
-{"APIDRA": 19.291730549696872, "CLOPIDOGREL": 10.420439882071758, "ENTRESTO": 58.2699137992591}
\ No newline at end of file
+{"ADVAGRAF": 71.83991164554432, "ARAVA": 0.6157794057933428, "ASPARAGINASE": 8.670192031147167, "CELLCEPT": 9.675017260262411, "CICLOSPORIN": 25.66877942153313, "CIMZIA": 1.9239556985554933, "COMIRNATY": 0.1841615624523158, "COSENTYX": 1.8864020161691089, "CYTARABINE": 3.7692094783503536, "DOXORUBICIN": 13.782308897792818, "ENTYVIO": 4.316292399039281, "JAKAVI": 4.579234646330851, "METHOTREXATE": 2.762894438955893, "PEGINTRON": 2.109318584747225, "RITUXIMAB": 7.015545716166528, "SIMPONI": 3.2690335574545224, "SPIKEVAX": 0.1556584051177365, "STELARA": 4.073738191177917, "XELJANZ": 1.3390171577982384, "YESCARTA": 25.700012548907285, "null": 0.4279973650336142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11830.json
new file mode 100644
index 00000000000..cfb4b0f5328
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11830.json
@@ -0,0 +1 @@
+{"SOLIRIS": 1157.985095658497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11831.json
new file mode 100644
index 00000000000..58f6384782d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11831.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 348.8484176362208, "null": 0.7375443275018408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11832.json
new file mode 100644
index 00000000000..c5c9f2cb83d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11832.json
@@ -0,0 +1 @@
+{"AVAMYS": 12.095119837781771, "BUDESONIDE": 26.147651963816056, "COMIRNATY": 0.3929465557585869, "CYTARABINE": 7.008477902584493, "MEPOLIZUMAB": 27.430351528167726, "PEGASYS": 1.631693282132419, "SPIKEVAX": 0.4529299617760015, "VAXZEVRIA": 0.2265115369644046, "null": 1.0247497487204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11833.json
new file mode 100644
index 00000000000..e373269ab39
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11833.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 1487.0384993080331, "ANORO": 60.44459068687416, "AVAMYS": 223.48572307956488, "GLYCOPYRRONIUM": 632.3955860102072, "NUCALA": 12.573680501635623, "OMALIZUMAB": 29.51938339625691, "null": 0.0837657153548328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11834.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11834.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11835.json
new file mode 100644
index 00000000000..76286fd3f4a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11835.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1742161413851326, "PREGABALIN": 31.879971441794368, "TOZINAMERAN": 0.912613611001408, "null": 3.594882131740196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11836.json
new file mode 100644
index 00000000000..3469f3f11cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11836.json
@@ -0,0 +1 @@
+{"EYLEA": 29.816399307331, "NEVANAC": 1116.2411709572875, "TOBRAMYCIN": 55.38051686224862, "null": 7.215980155859628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11837.json
new file mode 100644
index 00000000000..081783ce22f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11837.json
@@ -0,0 +1 @@
+{"null": 0.5712359299689306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11838.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11838.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11839.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11839.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1184.json
index ee595420ae8..cb6fe10cacf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1184.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 11.420850172538229, "AVAMYS": 45.72553826290113, "INSULIN": 8.290560281353107, "KAFTRIO": 20.14572561615075, "OLANZAPINE": 8.07268986998991, "ZOSTAVAX": 36.36773591746697, "ZYPREXA": 3.419602997968908}
\ No newline at end of file
+{"CARMUSTINE": 235.7076294463422, "CYTARABINE": 56.52921272730367, "DEXAMETHASONE": 35.471914707345675, "DOXORUBICIN": 86.78978224602395, "MABTHERA": 87.60224945377034, "RITUXIMAB": 62.3018031835912, "null": 0.4597636335005375}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11840.json
new file mode 100644
index 00000000000..3f295c6ea26
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11840.json
@@ -0,0 +1 @@
+{"BUSULFAN": 3.9532227230794126, "CANCIDAS": 9.512090790117238, "CELLCEPT": 1.5492025690980404, "CICLOSPORIN": 10.72550901098341, "CYTARABINE": 1.3694648757444217, "DEXAMETHASONE": 1.479859568977172, "EMEND": 15.906703000170758, "FENTANYL": 1.2091680267710263, "KEPPRA": 3.491450045099876, "LEVETIRACETAM": 3.5640887841101803, "LEVOFLOXACIN": 1.6367435802297532, "LYRICA": 2.218586326170255, "OLANZAPINE": 0.9717707506599902, "PEGINTRON": 0.6762556830901004, "PREGABALIN": 3.9061073711505663, "VFEND": 1.62842464698937, "null": 6.167676556483212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11841.json
new file mode 100644
index 00000000000..65dcb0a8205
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11841.json
@@ -0,0 +1 @@
+{"1": 102.8388320701753, "ACTRAPID": 14.423900937408742, "ADENURIC": 2.7390671207000667, "ALIMTA": 2.695801025604946, "AMIKACIN": 2.5171902050598183, "AP": 162.71917378687976, "APIXABAN": 0.4324847078785285, "APROVEL": 1.5703593736760113, "ARANESP": 0.5288714580445433, "ARAVA": 0.1374675817722987, "ARIPIPRAZOLE": 0.5024125825071598, "AUBAGIO": 0.4024234653511695, "AZARGA": 188.7290780133875, "AZOPT": 146.66405515416187, "BUDESONIDE": 0.4837765320669521, "BUSULFAN": 0.8868318698102156, "CAELYX": 2.360747061845563, "CANCIDAS": 17.44600546216288, "CASPOFUNGIN": 13.241548939717738, "CELLCEPT": 0.5341836432846466, "CHAMPIX": 0.1714679180449939, "CICATRIZANTS": 142.10352587642558, "CICLOSPORIN": 1.212712185991003, "CLOPIDOGREL": 0.4057699379333312, "COMBIVIR": 1.5264097263377292, "COMIRNATY": 0.0107404582184985, "COTELLIC": 2.310534855042937, "CUBICIN": 4.194768165959792, "CYMBALTA": 0.0961521125048355, "CYTARABINE": 1.7603941629984672, "DAPTOMYCIN": 8.955312494502156, "DEXAMETHASONE": 3.321630748138414, "DOCETAXEL": 1.0281688340959394, "DOXORUBICIN": 1.5675494236052534, "ELIQUIS": 0.2603827827396181, "EMEND": 32.75162207631664, "ENOXAPARIN": 4.010032450121238, "ERLEADA": 13.41073305438618, "ESOMEPRAZOLE": 3.1701049301345043, "EUGALAN": 1310.0945573625113, "FEBUXOSTAT": 6.188260503623746, "FENTANYL": 1.506702202388844, "FILGRASTIM": 2.8568773211861616, "FYCOMPA": 5.53517838660358, "GLIBENCLAMIDE": 4.464358534980282, "HALAVEN": 1.889508775481776, "HUMAN": 2.576332795993969, "HYDROCORTISONE": 2.70531269600856, "IBUPROFEN": 8.512865051486944, "IPILIMUMAB": 3.686371464834559, "IRESSA": 1.7911693345167456, "JANUVIA": 0.5581307980978442, "KALETRA": 0.8486549661379871, "KEPPRA": 5.79554026742011, "KEYTRUDA": 3.4437704613405997, "KIVEXA": 7.03745897433159, "KONTRASTMITTEL": 240.08497729088683, "LACOSAMIDE": 3.7998664101949, "LAMIVUDINE": 5.688526498137124, "LANTUS": 0.0990627963461554, "LEVEMIR": 0.5284776828107253, "LEVETIRACETAM": 6.027602506804378, "LEVOFLOXACIN": 6.667232230731926, "LYRICA": 0.891798121272875, "MABTHERA": 1.8795697030027203, "MANNITOL": 18.609102870062333, "METHOTREXATE": 0.3019648269277085, "NEVIRAPINE": 42.56978628869768, "NEXAVAR": 0.5216830875960465, "NOT": 3.466140014766302, "NOVORAPID": 0.4579068042379849, "OLANZAPINE": 0.5793174825711588, "OPDIVO": 2.503009088371614, "OSELTAMIVIR": 7.349449915721306, "PANTOPRAZOLE": 6.32205314947949, "PEGASYS": 0.383336220634147, "PEGINTRON": 0.3020878735190995, "PEMBROLIZUMAB": 5.781438134847835, "PEMETREXED": 3.070247010802734, "PLAVIX": 1.2689191116809573, "POTELIGEO": 10.77964029755511, "PRADAXA": 3.1513804044082283, "PREGABALIN": 1.1489491890097323, "SIFROL": 3.383928282951689, "SPIKEVAX": 0.0097124381937, "SPIRONOLACTONE": 2.256699705217657, "STIVARGA": 0.7347024928853231, "SUFENTANIL": 2.765564380201957, "SUTENT": 0.1769658910559317, "TAMIFLU": 7.452641959325338, "TELMISARTAN": 2.0374826664606847, "TEMODAL": 4.94899784780584, "TOBRAMYCIN": 8.230342361227871, "TRUVADA": 0.1095116603186645, "VAXZEVRIA": 0.0076011940645749, "VEMURAFENIB": 8.0105525505254, "VFEND": 2.7803196286874434, "VIMPAT": 1.0759341058657952, "VIRAMUNE": 21.714389466617284, "VORICONAZOLE": 3.840935485416468, "ZELBORAF": 5.085962498058287, "ZYPREXA": 0.173940070037951, "null": 3.2366860807407374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11842.json
new file mode 100644
index 00000000000..1477bdc46dd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11842.json
@@ -0,0 +1 @@
+{"null": 1.7597236085888186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11843.json
new file mode 100644
index 00000000000..76f8da6795f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11843.json
@@ -0,0 +1 @@
+{"null": 1.5042845022256706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11844.json
new file mode 100644
index 00000000000..766ec68438a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11844.json
@@ -0,0 +1 @@
+{"null": 1.7690326142898176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11845.json
new file mode 100644
index 00000000000..a6a24cabe60
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11845.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11846.json
new file mode 100644
index 00000000000..e119afc6fe1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11846.json
@@ -0,0 +1 @@
+{"PEGASYS": 5.732189841457928, "null": 2.2895589493966546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11847.json
new file mode 100644
index 00000000000..eb50b68f82e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11847.json
@@ -0,0 +1 @@
+{"null": 0.8065890883507018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11848.json
new file mode 100644
index 00000000000..c4f9a5c0ac9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11848.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11849.json
new file mode 100644
index 00000000000..1a0fe126234
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11849.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1185.json
index 75f0e3b0208..de58c485525 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1185.json
@@ -1 +1 @@
-{"IBRANCE": 133.49193267964904, "INLYTA": 124.65937704731576}
\ No newline at end of file
+{"CYTARABINE": 112.08803591853076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11850.json
new file mode 100644
index 00000000000..edb896d6f81
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11850.json
@@ -0,0 +1 @@
+{"FENTANYL": 16.32806617133635, "null": 5.886369586720847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11851.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11851.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11852.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11852.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11853.json
new file mode 100644
index 00000000000..9765bf20d8b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11853.json
@@ -0,0 +1 @@
+{"ABACAVIR": 6.091908032087636, "BUSULFAN": 62.74887632054162, "CELLCEPT": 20.32575276504653, "CICLOSPORIN": 16.439159816584397, "COMIRNATY": 0.1322111571722809, "KALETRA": 16.599940512111324, "null": 0.5262895595315394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11854.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11854.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11855.json
new file mode 100644
index 00000000000..4aaa098c249
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11855.json
@@ -0,0 +1 @@
+{"null": 1.1886398168110262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11856.json
new file mode 100644
index 00000000000..9267f17ed47
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11856.json
@@ -0,0 +1 @@
+{"null": 6.798293997947634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11857.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11857.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11858.json
new file mode 100644
index 00000000000..55c409669be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11858.json
@@ -0,0 +1 @@
+{"STELARA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11859.json
new file mode 100644
index 00000000000..ea3a48c03a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11859.json
@@ -0,0 +1 @@
+{"null": 1.2747282998417533}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1186.json
index 0e7ee229d3b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1186.json
@@ -1 +1 @@
-{"IBRANCE": 127.41102751754788}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11860.json
new file mode 100644
index 00000000000..1d7cd2013fd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11860.json
@@ -0,0 +1 @@
+{"LENVIMA": 526.8247248548116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11861.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11861.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11862.json
new file mode 100644
index 00000000000..65d81bd57cd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11862.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 19.177322174650165, "NEXAVAR": 13.416407925936026, "null": 0.3310573758213579}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11863.json
new file mode 100644
index 00000000000..6327abbf599
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11863.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9801013705343156, "null": 1.191905231702337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11864.json
new file mode 100644
index 00000000000..0031cad72cd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11864.json
@@ -0,0 +1 @@
+{"null": 1.8319878193573496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11865.json
new file mode 100644
index 00000000000..28c9315c5fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11865.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11866.json
new file mode 100644
index 00000000000..f244519fff4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11866.json
@@ -0,0 +1 @@
+{"null": 2.3276181966549254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11867.json
new file mode 100644
index 00000000000..e2cfb19f9f1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11867.json
@@ -0,0 +1 @@
+{"null": 3.3413779472227416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11868.json
new file mode 100644
index 00000000000..eb353fb098b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11868.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.0991217514140068, "SPIKEVAX": 1.5107813654727609, "VAXZEVRIA": 0.7851228919674613, "null": 0.9542215025007847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11869.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11869.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1187.json
index dd71117f6d2..6cc0aea1106 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1187.json
@@ -1 +1 @@
-{"ABATACEPT": 2.2542450274397665, "COVID19": 25.14779783555042, "SPIKEVAX": 1.2673517018055918, "TOZINAMERAN": 1.2202267640616886, "VAXZEVRIA": 3.329747324983579}
\ No newline at end of file
+{"SIMPONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11870.json
new file mode 100644
index 00000000000..778f4aad1f0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11870.json
@@ -0,0 +1 @@
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11871.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11871.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11872.json
new file mode 100644
index 00000000000..3a1d72d296e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11872.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3380963873358449, "null": 1.3995370933171878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11873.json
new file mode 100644
index 00000000000..9855d194728
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11873.json
@@ -0,0 +1 @@
+{"BLINATUMOMAB": 144.28751527791215, "COMIRNATY": 0.7310991951631508, "SYNAGIS": 36.95692845609894, "VAXZEVRIA": 0.2356052771745669, "null": 1.1826656768955566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11874.json
new file mode 100644
index 00000000000..354c7b90694
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11874.json
@@ -0,0 +1 @@
+{"XTANDI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11875.json
new file mode 100644
index 00000000000..2145b83ab66
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11875.json
@@ -0,0 +1 @@
+{"AZTREONAM": 751.2570500801398, "null": 1.6789761039612243}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11876.json
new file mode 100644
index 00000000000..4f7cb8d6fae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11876.json
@@ -0,0 +1 @@
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11877.json
new file mode 100644
index 00000000000..4f7cb8d6fae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11877.json
@@ -0,0 +1 @@
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11878.json
new file mode 100644
index 00000000000..5f97310265c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11878.json
@@ -0,0 +1 @@
+{"TRELEGY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11879.json
new file mode 100644
index 00000000000..1ad312eaa3f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11879.json
@@ -0,0 +1 @@
+{"IBUPROFEN": 25.90013908488394, "null": 0.9305655115667494}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1188.json
index 2741ebaa7c8..9f1dfa34567 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1188.json
@@ -1 +1 @@
-{"ABILIFY": 2.296994289177632, "COMIRNATY": 1.7502122025723452, "COVID19": 6.409983627235924, "NEULASTA": 3.370314982099754, "SPIKEVAX": 1.919465318303032, "TOZINAMERAN": 2.791561788204352, "VAXZEVRIA": 3.1710252156394705}
\ No newline at end of file
+{"ENBREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11880.json
new file mode 100644
index 00000000000..f1315de5a5b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11880.json
@@ -0,0 +1 @@
+{"null": 2.990564827583219}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11881.json
new file mode 100644
index 00000000000..d20a3d4425a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11881.json
@@ -0,0 +1 @@
+{"AVAMYS": 46.54538184559989, "NAGLAZYME": 95.33772042909148, "NUCALA": 17.984880750129616, "null": 1.6328234125980337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11882.json
new file mode 100644
index 00000000000..4f7cb8d6fae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11882.json
@@ -0,0 +1 @@
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11883.json
new file mode 100644
index 00000000000..cce428ef306
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11883.json
@@ -0,0 +1 @@
+{"ELIQUIS": 1.8751409475906384, "NAGLAZYME": 78.00385813281233, "SPINRAZA": 23.75630104692188, "TRACLEER": 17.597883895440866, "null": 1.206592401004396}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11884.json
new file mode 100644
index 00000000000..6053a45d8ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11884.json
@@ -0,0 +1 @@
+{"NAGLAZYME": 269.09333044475574, "SPINRAZA": 263.044119806319, "null": 0.2974667307030956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11885.json
new file mode 100644
index 00000000000..21137d8788c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11885.json
@@ -0,0 +1 @@
+{"null": 1.8744381314619465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11886.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11886.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11887.json
new file mode 100644
index 00000000000..300229ae4d9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11887.json
@@ -0,0 +1 @@
+{"MICARDIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11888.json
new file mode 100644
index 00000000000..fdaf3142e46
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11888.json
@@ -0,0 +1 @@
+{"null": 0.7592128051040704}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11889.json
new file mode 100644
index 00000000000..76a17a67278
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11889.json
@@ -0,0 +1 @@
+{"CIMZIA": 6.794205207600851, "DEXAMETHASONE": 11.410009442944698, "null": 0.8493626458599391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1189.json
index c464f4e2769..1ab65ac421a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1189.json
@@ -1 +1 @@
-{"ABILIFY": 2.4353530300096207, "AFINITOR": 6.274821373163245, "APIDRA": 1.7534827120676488, "APIXABAN": 1.0442602683568094, "BEVACIZUMAB": 7.178577943965769, "COSENTYX": 3.966487771424029, "COVID19": 1.2265886952099, "DULOXETINE": 3.8481525265923953, "EVEROLIMUS": 5.794183636533713, "IRBESARTAN": 4.212431284272316, "LUTETIUM": 29.588294205029012, "METHOTREXATE": 6.254419221704143, "MMRVAXPRO": 6.548659433986612, "NOT": 3.2569288712147344, "OMALIZUMAB": 24.374644575433223, "PANTOPRAZOLE": 20.32743252237411, "RITUXIMAB": 6.60255723606904, "SYNAGIS": 2.173370207569456, "TAMIFLU": 3.3078819957721097, "TOZINAMERAN": 1.0008887765351, "VAXZEVRIA": 1.2136868971148158, "XOLAIR": 2.679584000995417, "ZOSTAVAX": 1.0253005494584253}
\ No newline at end of file
+{"KYMRIAH": 203.59502564334872, "null": 0.3095524625314367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11890.json
new file mode 100644
index 00000000000..9e99f4e4f73
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11890.json
@@ -0,0 +1 @@
+{"null": 1.3940275783800191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11891.json
new file mode 100644
index 00000000000..76504c34516
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11891.json
@@ -0,0 +1 @@
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2.5440814890789185, "LIXIANA": 1.6224473456579978, "LYNPARZA": 0.5554879872428918, "LYRICA": 0.5961127233062645, "MABTHERA": 1.1848058893124442, "MAVENCLAD": 1.812363432913245, "MEKINIST": 1.712846231576142, "MERCAPTOPURINE": 1.7484985441075642, "METHOTREXATE": 2.978943883130511, "MICARDIS": 0.3773295798831409, "MIDAZOLAM": 0.9350576340655156, "MIMPARA": 3.110196568457165, "MULTAQ": 10.02760317782628, "MYCAMINE": 9.102907153273328, "MYCOPHENOLATE": 0.813859923122364, "NEXAVAR": 3.54611574032456, "NILOTINIB": 2.0238706312866928, "NIMENRIX": 0.3594318201678932, "NIVOLUMAB": 3.3959035460486606, "NORVIR": 4.016202346785162, "NOVONORM": 3.154267107364038, "NOXAFIL": 2.3728484579234226, "OCALIVA": 2.723856327905716, "OFEV": 8.834113485337948, "OLANZAPINE": 2.776344412093615, "OLYSIO": 4.391106423952661, "ONCASPAR": 1.6655136041491727, "OPDIVO": 0.5940114045852438, "OPSUMIT": 0.2675443290475344, "ORKAMBI": 3.7716131152085945, "PACLITAXEL": 3.3645048476009856, "PANTOPRAZOLE": 1.8978937111606016, "PAZOPANIB": 10.600677984415272, "PEGASYS": 1.6713146995302053, "PEGINTERFERON": 2.1329648312555927, "PEGINTRON": 0.8044638309314209, "PEMBROLIZUMAB": 1.334682811579565, "PEMETREXED": 1.7468000525454006, "PIRFENIDONE": 3.391201240927147, "PLAVIX": 1.0312413925602155, "PLEGRIDY": 1.9118560555701256, "PRADAXA": 1.4156529554287107, "PROTELOS": 3.2854570849290208, "RAPAMUNE": 1.1513358176251929, "REBETOL": 1.973354427813624, "REMDESIVIR": 19.29736854667308, "REYATAZ": 8.08946859812855, "RIBAVIRIN": 1.1726499733196571, "RIBOCICLIB": 5.981890159573674, "RINVOQ": 3.2627674513934024, "RISPERIDONE": 1.2399727172263908, "RITUXIMAB": 0.3517281319081374, "ROACTEMRA": 5.400556593888021, "RUBRACA": 2.0768802844656045, "RUXOLITINIB": 1.3112501736685511, "SAXENDA": 1.007982317524902, "SIMPONI": 0.4175144719427206, "SOLIRIS": 0.4045776131063433, "SPIKEVAX": 0.0399083410237766, "SPINRAZA": 1.3224253894095988, "SPRYCEL": 0.3725149771782834, "STELARA": 0.8629504280654684, "STIVARGA": 3.523020840070469, "STOCRIN": 8.51162050351136, "STRIBILD": 0.2875907338593793, "SUTENT": 0.8667819337173842, "TAGRISSO": 1.1281765817429747, "TAMIFLU": 2.5257206063569435, "TASIGNA": 2.405306441677729, "TEMODAL": 1.466034485277962, "TEMOZOLOMIDE": 1.475878298445461, "TIVICAY": 3.536039119157437, "TOCILIZUMAB": 4.725558606344496, "TOZINAMERAN": 0.0151489442733259, "TRABECTEDIN": 26.37806459325664, "TRACLEER": 2.8908588193518145, "TREMFYA": 1.2886860410278382, "TRIUMEQ": 4.686827155252556, "TRULICITY": 0.4950512928888441, "TRUVADA": 0.1827809752976177, "TWINRIX": 5.664801902142974, "VAXZEVRIA": 0.0196633952236015, "VEKLURY": 33.74729526364081, "VEMLIDY": 7.901138314145728, "VENCLYXTO": 1.568195359669329, "VENETOCLAX": 1.2147629237031583, "VFEND": 5.769196684223718, "VICTOZA": 0.340766343116707, "VIMPAT": 0.5472703159744642, "VIRAMUNE": 5.905342404948623, "VIREAD": 1.0417522291908312, "VORICONAZOLE": 3.703177262770708, "VOTRIENT": 5.283069604041435, "XALKORI": 4.761395478542955, "XARELTO": 1.529738116814048, "XELJANZ": 0.2870646107280954, "XELODA": 1.2982901292954472, "XOLAIR": 0.1994536285605045, "XTANDI": 0.2714178617484968, "YERVOY": 1.7748680696256234, "YONDELIS": 20.57170528979911, "ZELBORAF": 1.4187771136156817, "ZEPATIER": 4.709964387861108, "ZYPREXA": 2.405301742406869, "null": 1.6535355661785185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11892.json
new file mode 100644
index 00000000000..9cf2cbedaea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11892.json
@@ -0,0 +1 @@
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11893.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11893.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11894.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11894.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11895.json
new file mode 100644
index 00000000000..e9cc22234ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11895.json
@@ -0,0 +1 @@
+{"null": 1.8643337597253196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11896.json
new file mode 100644
index 00000000000..1fa6dff8f1b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11896.json
@@ -0,0 +1 @@
+{"PEGINTRON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11897.json
new file mode 100644
index 00000000000..5d5c7e0e854
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11897.json
@@ -0,0 +1 @@
+{"null": 2.2144925975589014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11898.json
new file mode 100644
index 00000000000..ee97d075011
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11898.json
@@ -0,0 +1 @@
+{"null": 0.5715039433069553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11899.json
new file mode 100644
index 00000000000..ce37959db08
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11899.json
@@ -0,0 +1 @@
+{"JAKAVI": 418.1555060069535, "KYMRIAH": 77.33313869724412, "null": 0.2180040142414411}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/119.json
index c185e7e0256..04a0c2b145e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/119.json
@@ -1 +1 @@
-{"ABACAVIR": 4.209149135288143, "BEVACIZUMAB": 9.442356420260865, "NEXAVAR": 3.1720363172057837, "null": 1.2323193776817416}
\ No newline at end of file
+{"JARDIANCE": 46.38392341528336, "NOVORAPID": 31.506410387441605, "null": 0.4134154155179135}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1190.json
index 306c75e33a4..37205bf0439 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1190.json
@@ -1 +1 @@
-{"AVAMYS": 3.95702087283585, "COMIRNATY": 1.37985535756883, "COVID19": 3.963407861483574, "GARDASIL": 4.574679359891302, "HYDROCORTISONE": 9.525873603337748, "MEKINIST": 3.6736529871470096, "SPIKEVAX": 1.1803390871970458, "TOZINAMERAN": 2.6768418020425573, "VAXZEVRIA": 1.444307329480443}
\ No newline at end of file
+{"KYMRIAH": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11900.json
new file mode 100644
index 00000000000..4845732a7b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11900.json
@@ -0,0 +1 @@
+{"ABILIFY": 3.2791463799900336, "ADCIRCA": 5.3137371965168825, "ADEMPAS": 7.489274457862896, "AMBRISENTAN": 10.481514586680497, "ARANESP": 14.325729673479849, "ARAVA": 0.145061162083636, "BENLYSTA": 1.6123201651151948, "CLOPIDOGREL": 2.19942151314485, "COMIRNATY": 0.0162470698415485, "DARZALEX": 3.9783031878922097, "ELIQUIS": 21.277319007104893, "EPOETIN": 24.32321647747281, "EXJADE": 1.9515997100198823, "GARDASIL": 0.9521521401907876, "IBRANCE": 0.9223281832937004, "INCIVO": 3.2554820930583794, "IPILIMUMAB": 2.311058722106648, "JANUVIA": 1.139058975813834, "KEYTRUDA": 2.2354147062818197, "LONSURF": 11.417484940528787, "NEULASTA": 9.371017235375414, "OPSUMIT": 33.65481317051211, "PEGASYS": 8.967226893388936, "PEGINTERFERON": 10.60633124393717, "PEGINTRON": 20.685621712119307, "PLAVIX": 1.250530721655365, "RIBAVIRIN": 6.069081172467718, "ROTATEQ": 2.1698440744487995, "RUBRACA": 9.138928960232992, "SOLIRIS": 16.586307763841816, "SPIKEVAX": 0.060225748541877, "SPRYCEL": 8.58733568032972, "TRACLEER": 17.948926901163937, "VELTASSA": 5.369868749684438, "VOTRIENT": 2.1073581788693665, "XOFIGO": 5.447121828592839, "XTANDI": 1.7134127590420627, "null": 0.6433529717041166}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11901.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11901.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11902.json
new file mode 100644
index 00000000000..ab492ca9f69
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11902.json
@@ -0,0 +1 @@
+{"ARANESP": 25.49537708645038, "EXJADE": 17.444916406238743, "HUMIRA": 27.55151702735323, "PRIVIGEN": 78.28952849617232, "SOLIRIS": 20.783353595345805, "null": 1.0293073018383214}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11903.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11903.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11904.json
new file mode 100644
index 00000000000..243a9ae60bd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11904.json
@@ -0,0 +1 @@
+{"PRIVIGEN": 251.752729541161, "null": 1.6587268853734356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11905.json
new file mode 100644
index 00000000000..13cd6e7664c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11905.json
@@ -0,0 +1 @@
+{"FLEBOGAMMA": 132.70451860679563, "HUMAN": 195.13001523224176, "PRIVIGEN": 120.28558772999926, "null": 1.4343025962740328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11906.json
new file mode 100644
index 00000000000..719fd4f09f1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11906.json
@@ -0,0 +1 @@
+{"HUMAN": 230.7709572705533, "PRIVIGEN": 97.05753103994792, "null": 1.032931810283628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11907.json
new file mode 100644
index 00000000000..176fd54c2ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11907.json
@@ -0,0 +1 @@
+{"TESTOSTERONE": 3969.856152227744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11908.json
new file mode 100644
index 00000000000..0e472734f68
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11908.json
@@ -0,0 +1 @@
+{"BYDUREON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11909.json
new file mode 100644
index 00000000000..592b865b11c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11909.json
@@ -0,0 +1 @@
+{"null": 0.3411798989533218}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1191.json
index efe01977795..5d7e95e036c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1191.json
@@ -1 +1 @@
-{"ABATACEPT": 1.489018836917922, "ARAVA": 1.6526309166182054, "BETAFERON": 1.0376401542185505, "BEXSERO": 2.7076601556616646, "CHLORHEXIDINE": 1.3052081214120963, "CIMZIA": 1.3694139921715405, "COMIRNATY": 2.432804654573451, "COTELLIC": 1.002961250760132, "COVID19": 2.7458390831097987, "FLEBOGAMMA": 6.951221013208412, "HEXACIMA": 10.32958251899102, "HYQVIA": 1.534730850355305, "INFANRIX": 1.0838549217019118, "KESIMPTA": 4.055517813646709, "KIOVIG": 5.35426907012695, "LEMTRADA": 1.5526013966133108, "MMRVAXPRO": 3.589282046461688, "NAGLAZYME": 5.537805575717448, "NIMENRIX": 3.0589154877873166, "OMALIZUMAB": 1.335803983887977, "PLEGRIDY": 1.20163018999236, "PREVENAR": 1.1820090388198885, "PRIVIGEN": 3.790242614227624, "SHINGRIX": 1.25864275066793, "SPIKEVAX": 2.7868887318038764, "TEDUGLUTIDE": 3.9373600003290776, "VAXZEVRIA": 5.30272117020829}
\ No newline at end of file
+{"KYMRIAH": 1929.585872279043}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11910.json
new file mode 100644
index 00000000000..0e8b93999be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11910.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.9171797303879257, "VAXZEVRIA": 1.4888476844430674, "null": 0.2899375830710506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11911.json
new file mode 100644
index 00000000000..866b4c88166
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11911.json
@@ -0,0 +1 @@
+{"KALYDECO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11912.json
new file mode 100644
index 00000000000..913a1795dae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11912.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.2032374644995396, "SILDENAFIL": 23.607594090671142, "SPIKEVAX": 0.7788029718770525, "TOZINAMERAN": 0.5532969678980404, "VAXZEVRIA": 1.146475650255428, "VIAGRA": 24.61715033783391, "null": 0.9151321105638572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11913.json
new file mode 100644
index 00000000000..c3e7a58de14
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11913.json
@@ -0,0 +1 @@
+{"ADENURIC": 2.1805591176586105, "AIMOVIG": 0.9763244209120664, "ANORO": 0.7510060257087451, "APIDRA": 0.4957815936182358, "APIXABAN": 1.4531416052639208, "APROVEL": 1.503087851483305, "ARANESP": 1.0692086861997798, "ARAVA": 0.0521832127115957, "AUBAGIO": 0.5432596725502566, "AVANDAMET": 23.62075395691535, "AVANDIA": 22.866042068495744, "AVASTIN": 1.2022325777018306, "BENLYSTA": 0.911934307194977, "BETMIGA": 1.3148126033761969, "BRILIQUE": 0.7850054668553209, "BYDUREON": 2.489850608165644, "BYETTA": 1.0435255146425664, "CHAMPIX": 1.2861120894360176, "CICLOSPORIN": 0.2234704251500661, "CIMZIA": 0.2399662428066171, "CLOPIDOGREL": 3.079911294033941, "COMIRNATY": 0.7071765256758887, "COSENTYX": 0.2885256296510218, "CYMBALTA": 0.7887305185398485, "DASATINIB": 3.63460650735159, "DEXAMETHASONE": 0.7268203592646917, "ELIQUIS": 7.189469854020823, "ENBREL": 0.2057773627334702, "ENTRESTO": 1.2661363294416708, "ENTYVIO": 0.6177409896839675, "ERLEADA": 1.1480035572946112, "ESBRIET": 1.3557038911736146, "EVENITY": 8.15057614678674, "EVISTA": 11.778833715242884, "EXFORGE": 1.0961033473700603, "EXJADE": 0.280301904441145, "EYLEA": 7.289906434768197, "FASENRA": 0.5030867295808518, "FASLODEX": 0.316353463776624, "FENTANYL": 0.2037156405327931, "FESOTERODINE": 51.72925328426641, "FILGRASTIM": 1.5131424717984965, "FORSTEO": 1.120421239042839, "FORXIGA": 0.8679055978206518, "GALAFOLD": 5.38140934991934, "GARDASIL": 0.0893421163662474, "HARVONI": 0.667369269479124, "HIZENTRA": 2.062837444756539, "HUMALOG": 1.9502863188831396, "HUMAN": 0.6719746145532308, "HUMIRA": 0.5039657697582758, "IBRANCE": 0.2927692134912887, "IBUPROFEN": 0.3536410708965783, "ICLUSIG": 3.4443135580174005, "INLYTA": 1.2389813107951386, "INSULIN": 0.596191571165703, "IRINOTECAN": 0.8606893828436656, "JAKAVI": 0.3107635430939732, "JANUMET": 0.645278013336175, "JANUVIA": 0.7744821669336299, "JARDIANCE": 1.042435996885665, "KEPPRA": 0.434260964454688, "KEYTRUDA": 0.2540195877659831, "LANTUS": 1.927636273316656, "LATUDA": 1.3333413171667032, "LEVEMIR": 0.9462735204812984, "LIXIANA": 3.9484359472683495, "LYRICA": 0.7365784525621819, "MEKINIST": 0.6009844788178863, "MEMANTINE": 4.296264435910807, "MEPOLIZUMAB": 2.0425540552557746, "METHOTREXATE": 0.2631030074032522, "MICARDIS": 1.6771433586987423, "MODERNA": 0.2473358009810962, "MULTAQ": 1.0501523911222488, "NEXAVAR": 0.4688367890268827, "NPLATE": 1.7397408646420771, "NUCALA": 0.3852045085133099, "OFEV": 2.369054124380918, "OPSUMIT": 0.4618963334503501, "PEGASYS": 0.8449666487645251, "PEGINTRON": 1.3895243265922432, "PLAVIX": 6.968408762300268, "PRADAXA": 2.454275727849093, "PRIVIGEN": 0.7115074946209926, "PROTELOS": 3.058145567068717, "REVATIO": 0.7854224736003387, "RIBAVIRIN": 0.5220006902948722, "RINVOQ": 1.4879981642070876, "ROACTEMRA": 0.9275525844753716, "ROSIGLITAZONE": 10.861642518248212, "SAXENDA": 0.7787568737767463, "SHINGRIX": 0.6123559198880819, "SIMPONI": 0.515922937672491, "SOLIRIS": 0.5688173669085634, "SPIKEVAX": 0.4979968432361892, "SPRYCEL": 0.3633062883072827, "STELARA": 1.1044853505566683, "SUTENT": 0.9564093913584916, "TAMIFLU": 0.8872987316890071, "TASIGNA": 4.39049241310469, "THALIDOMIDE": 2.8797802067650737, "TOUJEO": 0.8959283227775683, "TOVIAZ": 0.6376763053015378, "TOZINAMERAN": 1.092839598199933, "TRACLEER": 0.3393342686486199, "TRELEGY": 0.5224212465113334, "TRULICITY": 0.8849613475036631, "VALSARTAN": 1.5054061145837203, "VAXZEVRIA": 0.896191610737293, "VIAGRA": 2.4243683607311506, "VICTOZA": 1.072155405689148, "VOTRIENT": 1.9056593226816811, "XARELTO": 1.8901997152883327, "XELJANZ": 0.8044343914111071, "XOLAIR": 1.808250852240558, "XTANDI": 1.510740358905945, "ZOSTAVAX": 1.6505871243239951, "ZYPREXA": 1.0625864571165726, "null": 0.8619950176897822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11914.json
new file mode 100644
index 00000000000..70b227a9a8b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11914.json
@@ -0,0 +1 @@
+{"null": 1.839196798798022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11915.json
new file mode 100644
index 00000000000..b55fd217cbc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11915.json
@@ -0,0 +1 @@
+{"ABILIFY": 47.00805777255162, "SUBOXONE": 15.911441040586269, "null": 1.4680939152026782}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11916.json
new file mode 100644
index 00000000000..de55d62633b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11916.json
@@ -0,0 +1 @@
+{"BEOVU": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11917.json
new file mode 100644
index 00000000000..faa6172baa6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11917.json
@@ -0,0 +1 @@
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11918.json
new file mode 100644
index 00000000000..d8640e78910
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11918.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 23.52571976326648, "STELARA": 17.505632330890204, "null": 0.4699746803442351}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11919.json
new file mode 100644
index 00000000000..c02c6c43c4e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11919.json
@@ -0,0 +1 @@
+{"null": 4.607120531442375}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1192.json
index 5ce5bc0dfc4..72b435186cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1192.json
@@ -1 +1 @@
-{"VAXZEVRIA": 10.53434977722905}
\ No newline at end of file
+{"KESIMPTA": 284.462427783172, "RITUXIMAB": 30.972831522835538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11920.json
new file mode 100644
index 00000000000..2b2d33d3c42
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11920.json
@@ -0,0 +1 @@
+{"ARANESP": 72.57045032065763, "DARZALEX": 19.27926988112287, "EXJADE": 41.05791453028094, "ICLUSIG": 65.54273089259819, "KAFTRIO": 29.97997883974379, "MIMPARA": 44.51280032992484, "NOXAFIL": 31.952443550984203, "OPSUMIT": 33.653425722781826, "SPRYCEL": 8.925170501458705, "TRACLEER": 15.042368387265812, "VENETOCLAX": 41.37399124678456, "null": 0.6001037070763862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11921.json
new file mode 100644
index 00000000000..86e0c380dff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11921.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 23.621535539723585, "ARAVA": 2.7997389093436924, "BASILIXIMAB": 62.44376262482477, "CELLCEPT": 106.01671442815233, "CICLOSPORIN": 22.72702379006976, "DACLIZUMAB": 3214.066520857936, "DOXORUBICIN": 18.420336878493973, "GANCICLOVIR": 32.831780158127145, "MYCOPHENOLATE": 21.831008426222034, "SOLIRIS": 9.881373936101664, "SPIRONOLACTONE": 57.04879384223173, "null": 0.1890848736184142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11922.json
new file mode 100644
index 00000000000..77ac391710d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11922.json
@@ -0,0 +1 @@
+{"OPSUMIT": 193.72139584448232, "TRACLEER": 52.327285995031495, "null": 0.3332246179428434}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11923.json
new file mode 100644
index 00000000000..bbefdf087e6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11923.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 109.40141026983612, "BASILIXIMAB": 60.80451264147367, "BUSULFAN": 135.44738848086695, "CELLCEPT": 14.705322233712446, "CICLOSPORIN": 20.46824430436712, "MACI": 2971.3211525250745, "MYCOPHENOLATE": 28.338988784353685, "PEGINTERFERON": 9.662342030301026, "SOLIRIS": 16.047203225828323, "null": 0.3788065332165777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11924.json
new file mode 100644
index 00000000000..68c5bd160d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11924.json
@@ -0,0 +1 @@
+{"ADVAGRAF": 51.13837996140876, "ALEMTUZUMAB": 50.77694595102959, "AMIKACIN": 11.040073635175988, "ARANESP": 2.125253278576748, "ARAVA": 0.654023276441902, "AZATHIOPRINE": 9.658687321825788, "BASILIXIMAB": 159.5983932521416, "BUSULFAN": 19.308500607536377, "CELLCEPT": 69.9208144600189, "CICLOSPORIN": 28.33818345359945, "DACLIZUMAB": 600.2111679254759, "GANCICLOVIR": 52.58484420039505, "KEYTRUDA": 0.9651864680613236, "MYCOPHENOLATE": 82.47219106475374, "OLYSIO": 10.127033979340144, "PEGASYS": 0.6771619267652745, "PEGINTERFERON": 3.826532961537925, "PEGINTRON": 0.8907858961201446, "RAPAMUNE": 63.44327154322768, "SIROLIMUS": 68.93462089310147, "SOLIRIS": 24.01069495121897, "SPIKEVAX": 0.0538950753456991, "TACROLIMUS": 48.36680142436104, "TOZINAMERAN": 0.2295340667373047, "VAXZEVRIA": 0.0332853543343634, "VFEND": 3.4586118534115737, "null": 0.6363815406107881}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11925.json
new file mode 100644
index 00000000000..d5060f10b18
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11925.json
@@ -0,0 +1 @@
+{"null": 0.363987241145765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11926.json
new file mode 100644
index 00000000000..d3654237bc2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11926.json
@@ -0,0 +1 @@
+{"CYMBALTA": 3.6585421761180834, "IBUPROFEN": 15.149587955244677, "null": 5.136604364686465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11927.json
new file mode 100644
index 00000000000..2398573eef5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11927.json
@@ -0,0 +1 @@
+{"null": 1.489675645859152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11928.json
new file mode 100644
index 00000000000..a69846ea5de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11928.json
@@ -0,0 +1 @@
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11929.json
new file mode 100644
index 00000000000..1248834d493
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11929.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 29.499874221664477, "COMIRNATY": 1.112375552423008, "SPIKEVAX": 0.8908894648324731, "VAXZEVRIA": 3.785041360826914, "null": 0.3961710632952428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1193.json
index 28fb2846621..ea7a76aec18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1193.json
@@ -1 +1 @@
-{"ANAKINRA": 165.77864200420166}
\ No newline at end of file
+{"AXICABTAGENE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11930.json
new file mode 100644
index 00000000000..87762c14bdf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11930.json
@@ -0,0 +1 @@
+{"TOUJEO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11931.json
new file mode 100644
index 00000000000..4c076974747
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11931.json
@@ -0,0 +1 @@
+{"null": 3.440318901667623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11932.json
new file mode 100644
index 00000000000..00062f06ff1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11932.json
@@ -0,0 +1 @@
+{"ATRIPLA": 2.331468200956493, "ELIQUIS": 9.321520151281506, "null": 0.4272681169751124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11933.json
new file mode 100644
index 00000000000..1735fe4d578
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11933.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 3.859869555384456, "COMIRNATY": 0.0869374228625863, "ELIQUIS": 17.217695612954767, "PLAVIX": 20.1980851107826, "null": 1.6816611494583251}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11934.json
new file mode 100644
index 00000000000..c411a8eb668
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11934.json
@@ -0,0 +1 @@
+{"ELIQUIS": 30.610541926250917, "HEMLIBRA": 261.1155952554108, "KOVALTRY": 891.2060412906651, "PLAVIX": 10.824135349858803, "null": 1.1963228972629876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11935.json
new file mode 100644
index 00000000000..c2870a70757
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11935.json
@@ -0,0 +1 @@
+{"ELIQUIS": 16.531413688035972, "null": 0.6426137086339008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11936.json
new file mode 100644
index 00000000000..a0f02a29112
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11936.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 3.932315623516863, "ELIQUIS": 33.0561564087775, "ENTRESTO": 8.014231865138628, "PLAVIX": 25.096732539115838, "null": 1.1598877385319322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11937.json
new file mode 100644
index 00000000000..4284f50e3bb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11937.json
@@ -0,0 +1 @@
+{"null": 1.3394948856497373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11938.json
new file mode 100644
index 00000000000..b957c93032c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11938.json
@@ -0,0 +1 @@
+{"SPINRAZA": 2547.739059467472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11939.json
new file mode 100644
index 00000000000..a9a9e5d75fd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11939.json
@@ -0,0 +1 @@
+{"AVANDIA": 5.651198721492126, "BUSULFAN": 12.407910060299004, "COMIRNATY": 0.0622717209778005, "ELIQUIS": 2.6417418167355518, "RITUXIMAB": 6.138452567303527, "null": 1.730626361098368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1194.json
index b3aff87b404..9a0901d01f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1194.json
@@ -1 +1 @@
-{"AFINITOR": 6.003434854442488, "ELIQUIS": 2.2308208229308137, "FASLODEX": 14.068348745220472, "FULVESTRANT": 13.85700191686983, "IBRANCE": 5.625118308725822, "LANTUS": 1.7709745262603258, "VOTRIENT": 8.150892251551506, "XELJANZ": 1.3681487738299527, "XTANDI": 19.7788821453022, "null": 1.4084992277289925}
\ No newline at end of file
+{"ECULIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11940.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11940.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11941.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11941.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11942.json
new file mode 100644
index 00000000000..3be0a32944f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11942.json
@@ -0,0 +1 @@
+{"null": 0.5740692367070304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11943.json
new file mode 100644
index 00000000000..90685120a8a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11943.json
@@ -0,0 +1 @@
+{"ABACAVIR": 15.659686250359382, "ABATACEPT": 4.0608825263063775, "ADALIMUMAB": 5.551396039402764, "AFINITOR": 0.4272658666482434, "AIMOVIG": 2.367606621044246, "ALEMTUZUMAB": 0.6710692350767931, "AMIKACIN": 5.479122433260497, "AMINOSALICYLIC": 2.7115410232339574, "ANAKINRA": 12.594683094747708, "APIXABAN": 0.1315423949870442, "APREMILAST": 6.552691013964545, "ARAVA": 12.305489120989307, "ARIPIPRAZOLE": 1.3725520521607049, "ASPARAGINASE": 0.4476040153809216, "ATAZANAVIR": 3.569479142798458, "ATRIPLA": 0.0500433639960438, "AUBAGIO": 0.3118702897973503, "AVASTIN": 0.6900478909191913, "AZACITIDINE": 1.683648346694346, "AZATHIOPRINE": 10.164453622450583, "BASILIXIMAB": 1.978769907191391, "BEDAQUILINE": 3.448128834514656, "BEVACIZUMAB": 2.129863311728637, "BIKTARVY": 2.8643513062480093, "BLINATUMOMAB": 2.970588885580719, "BORTEZOMIB": 4.093463112350973, "BOSULIF": 0.5427786144813246, "BOSUTINIB": 5.603527813298479, "BOTULINUM": 5.2108896768913935, "BRIVARACETAM": 2.2359148514497305, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11944.json
new file mode 100644
index 00000000000..64d24fc862e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11944.json
@@ -0,0 +1 @@
+{"ABACAVIR": 5.69494683181208, "ABILIFY": 7.77534362298978, "ACTOS": 3.1324572071926275, "ACTRAPID": 3.8613732750715655, "ADEMPAS": 2.185169553759043, "ALISKIREN": 11.46758455041657, "AMIKACIN": 1.1831501755293536, "AMINOSALICYLIC": 2.521055693229441, "ANORO": 2.298776222213451, "APIDRA": 1.851227059639838, "APIXABAN": 0.3092532547791083, "ARAVA": 0.4232941364623935, "ARIPIPRAZOLE": 8.512895555328582, "ATAZANAVIR": 9.78315990389932, "ATRIPLA": 0.1509732710631996, "AUBAGIO": 0.3447940911152211, "BARACLUDE": 5.368834014042079, "BEDAQUILINE": 10.921704923575964, "BENLYSTA": 0.4704315787873576, "BETMIGA": 1.9859025729544575, "BEVACIZUMAB": 1.4020304151083465, "BIKTARVY": 15.8617401354794, "BRINTELLIX": 2.391842666124485, "BRIVIACT": 1.8479856544686664, "BUDESONIDE": 1.7375517545197516, "BUPRENORPHINE": 0.4785608947548405, "BYETTA": 0.7521930862286914, "CABOTEGRAVIR": 8.930505311324094, "CARIPRAZINE": 38.12952200795059, "CELLCEPT": 0.4576670048899708, "CELSENTRI": 16.09923868125667, "CHAMPIX": 0.1469185260002563, "CICLOSPORIN": 0.2723693362638457, "CIMZIA": 0.6277507234990278, "CLOPIDOGREL": 1.030821914381437, "COMBIVIR": 3.42792753702361, "CYMBALTA": 0.2220233461039457, "DACLATASVIR": 4.588858163537847, "DAKLINZA": 3.1361711498141025, "DARUNAVIR": 26.877044456513342, "DASATINIB": 4.429786961954401, "DELAMANID": 6.030996350635517, "DESCOVY": 11.055109358215985, "DOLUTEGRAVIR": 28.696180028118555, "DULOXETINE": 1.5840325980231884, "EFAVIRENZ": 7.938575362057783, "ELIQUIS": 5.870740415546925, "EMPAGLIFLOZIN": 2.065064144646137, "EMTRICITABINE": 11.136391395592392, "ENTACAPONE": 3.288600916973963, "ENTECAVIR": 4.781881495143108, "ENTYVIO": 5.679724196101415, "EPCLUSA": 12.993678037807232, "EPIVIR": 1.3060221307592343, "ERLEADA": 4.188343084493764, "ESBRIET": 0.618163636624217, "EXJADE": 3.1948857889591986, "FAMPYRA": 0.6880690941237789, "FIASP": 1.7949461760906795, "FORXIGA": 1.7411788022928016, "GANCICLOVIR": 1.313264696795119, "GENVOYA": 14.371531536341797, "GLIBENCLAMIDE": 3.5067249534129985, "HARVONI": 4.330842342696448, "HIZENTRA": 0.6293342380646427, "HUMALOG": 0.7316116914292162, "IBRANCE": 0.1837873263851507, "IBUPROFEN": 0.6923103588913994, "ICLUSIG": 4.464177811067646, "INCIVO": 2.0318202868733697, "INCRUSE": 1.430453824450424, "INSULIN": 4.471113214965504, "INVEGA": 15.917303404009376, "INVOKANA": 20.74200184961655, "IRBESARTAN": 1.0664747434427997, "ISENTRESS": 3.650256494998105, "JANUMET": 1.275011892952255, "JANUVIA": 1.2279168138827088, "JARDIANCE": 0.4237566563754327, "KAFTRIO": 1.9786755778623943, "KALETRA": 1.4118944344234587, "KALYDECO": 6.345985023492354, "KEPPRA": 3.0214907225936125, "KEYTRUDA": 0.1594622834241587, "LACOSAMIDE": 3.1059086895020696, "LAMIVUDINE": 4.319787513504023, "LANTUS": 1.6127420044607037, "LATUDA": 3.0342293954792225, "LEVEMIR": 3.8635770853449967, "LEVETIRACETAM": 2.425354681140929, "LEVOFLOXACIN": 0.6723355113304129, "LIXIANA": 2.443507723054619, "LURASIDONE": 13.187563734024057, "LYNPARZA": 0.7386360134663109, "LYRICA": 1.079395261648736, "MEPOLIZUMAB": 1.8551511192547328, "METFORMIN": 3.459413085796258, "METHOTREXATE": 0.582012796749162, "MICARDIS": 0.6432490746521174, "MIMPARA": 5.726543965145249, "MIXTARD": 5.101551800741766, "MYCOPHENOLATE": 1.4682946837524185, "NORVIR": 1.700089109452413, "NOVORAPID": 2.207262736819068, "NPLATE": 2.0192496068647863, "NUCALA": 0.8232638473065715, "OCALIVA": 3.8220451455064, "OLANZAPINE": 6.938109740420761, "OLYSIO": 2.5238475424439133, "OPSUMIT": 2.176947596948948, "ORKAMBI": 10.250656578709323, "PANTOPRAZOLE": 0.6916960658614429, "PEGASYS": 0.1530697533553366, "PEGINTERFERON": 0.7477436799527806, "PEGINTRON": 0.258820202176272, "PLAVIX": 0.6324187498777787, "PREGABALIN": 1.179513886025883, "RELVAR": 5.239383374540791, "RIBAVIRIN": 3.250176080624052, "RISPERIDONE": 2.541804564868382, "SAXENDA": 0.7444824940007818, "SIMPONI": 1.4338768205251124, "SOLIRIS": 2.0414957837531635, "SOVALDI": 3.1921722220004702, "SPRYCEL": 1.593317779117273, "STELARA": 1.7182069237959996, "STRIBILD": 1.5176108585814472, "SUBOXONE": 0.8966677029875781, "SUTENT": 0.0800213254955324, "SYCREST": 3.565968694159596, "SYMTUZA": 10.059402853288685, "TASIGNA": 0.466517789154824, "TENOFOVIR": 7.879381013301568, "TICAGRELOR": 2.6151451612268586, "TIVICAY": 6.366920213471998, "TRACLEER": 1.6302831920365504, "TRELEGY": 2.7858956747110306, "TREMFYA": 2.510377922529676, "TRESIBA": 4.4978892775475545, "TRIUMEQ": 5.5202989529101085, "TRUVADA": 0.9371367567169272, "VARENICLINE": 18.98929197707808, "VELTASSA": 8.344193946134597, "VEMLIDY": 9.15822564032372, "VICTOZA": 0.6499298921549367, "VIMPAT": 3.520220791017492, "VIREAD": 2.872559235244783, "VOTRIENT": 0.6538003077852683, "XARELTO": 2.304010127136201, "XELJANZ": 0.6405584530030783, "XOLAIR": 0.3255706453955347, "XTANDI": 5.955133806365104, "ZOSTAVAX": 0.1773795601944683, "ZYPREXA": 1.715756039606847, "null": 1.3946994161127355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11945.json
new file mode 100644
index 00000000000..1b8affe14f7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11945.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 0.8519254438140682, "ABATACEPT": 0.0309905433433924, "ABILIFY": 2.116342228729783, "ACLIDINIUM": 0.3548962602866657, "ACTOS": 1.5900321584543855, "ACTRAPID": 0.3166436019065861, "ADALIMUMAB": 0.0431913541277678, "ADCIRCA": 0.2682867989802836, "ADEMPAS": 0.3630405666796401, "ADVAGRAF": 1.828761345899053, "AERIUS": 0.9802707687412122, "AFINITOR": 0.1237413091537992, "AIMOVIG": 1.6085527701132416, "ALEMTUZUMAB": 0.5805949665091574, "ALIMTA": 0.1115194537108777, "ALL": 1.601123893648322, "AMIKACIN": 0.2266923810140059, "AMINOSALICYLIC": 0.0970444721711135, "ANORO": 0.7249465638608621, "ANTIBIOTICS": 0.9421917775919956, "APIDRA": 1.6947554977725412, "APIXABAN": 0.076596725010583, "APROVEL": 0.3892484409856945, "ARANESP": 0.1435112265509185, "ARAVA": 0.0290182526780718, "ARIPIPRAZOLE": 1.8721960750061104, "ARSENIC": 3.800906954118714, "ASPARAGINASE": 0.1626641360112411, "ATAZANAVIR": 0.3944501194633936, "ATRIPLA": 0.0092858853322576, "AUBAGIO": 1.0885200989616328, "AVAMYS": 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0.1575826552706752, "RUBRACA": 0.3422803661271178, "RYBELSUS": 0.2505662320876157, "SAXENDA": 0.3494288701829843, "SELINCRO": 5.122566615646435, "SHINGRIX": 0.5768862872926596, "SIFROL": 2.4657226615544543, "SILDENAFIL": 0.2421321477896128, "SIMPONI": 0.317063048679582, "SITAGLIPTIN": 2.0420126053534013, "SOLIRIS": 0.1843033828703335, "SOMATROPIN": 0.4230582421179571, "SOVALDI": 0.1532783379295665, "SPIKEVAX": 0.701382942045061, "SPINRAZA": 0.2349169980748962, "SPIRONOLACTONE": 0.3503587935109012, "SPRYCEL": 0.1989804189776978, "STALEVO": 4.080156149610642, "STELARA": 0.7289408325142556, "STIVARGA": 0.1269942443804765, "SUBOXONE": 1.379255182659345, "SUFENTANIL": 0.3553736470662375, "SUTENT": 0.2693159810555773, "SYCREST": 1.1683770363132209, "SYNAGIS": 0.1865054999510128, "TACROLIMUS": 1.1187426819879005, "TAFINLAR": 0.6966762559669404, "TAGRISSO": 0.1920225831096289, "TAMIFLU": 1.2897224242884693, "TASIGNA": 0.188416712279963, "TELMISARTAN": 0.7130534704070176, "TEMODAL": 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"XYREM": 2.796774550799063, "YERVOY": 0.2191820514647291, "YESCARTA": 2.9957418213089984, "ZAVESCA": 3.5464772880719093, "ZONISAMIDE": 1.363549676498441, "ZOSTAVAX": 0.320020378462962, "ZYPADHERA": 1.2865872635630025, "ZYPREXA": 1.827632111376888, "null": 1.6556446016703512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11946.json
new file mode 100644
index 00000000000..50aeb29ddb0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11946.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 56.30373403400948, "SUBOXONE": 75.9909684232489, "null": 2.2545453053453763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11947.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11947.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11948.json
new file mode 100644
index 00000000000..030666f2ec4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11948.json
@@ -0,0 +1 @@
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11949.json
new file mode 100644
index 00000000000..35946796742
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11949.json
@@ -0,0 +1 @@
+{"null": 0.2974667307030956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1195.json
index 69d626c2b7f..551dfc492db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1195.json
@@ -1 +1 @@
-{"FASLODEX": 49.590901015877954}
\ No newline at end of file
+{"CICLOSPORIN": 51.75661242028292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11950.json
new file mode 100644
index 00000000000..b161d5b57de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11950.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 102.50584938337224, "null": 0.9461359223348804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11951.json
new file mode 100644
index 00000000000..18d6fff2488
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11951.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 18.203958342709377, "null": 0.9230988997213112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11952.json
new file mode 100644
index 00000000000..7b5a8fdf8db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11952.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 18.722171113477295, "LEMTRADA": 105.44913636537528, "null": 2.167964153791813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11953.json
new file mode 100644
index 00000000000..4eae6a6a071
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11953.json
@@ -0,0 +1 @@
+{"LEMTRADA": 79.8700407430169, "null": 2.6823323238509174}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11954.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11954.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11955.json
new file mode 100644
index 00000000000..96b3835d685
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11955.json
@@ -0,0 +1 @@
+{"null": 0.9994281994518696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11956.json
new file mode 100644
index 00000000000..b2aa823fbd5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11956.json
@@ -0,0 +1 @@
+{"RUCONEST": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11957.json
new file mode 100644
index 00000000000..731a739207a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11957.json
@@ -0,0 +1 @@
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11958.json
new file mode 100644
index 00000000000..bd971f478d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11958.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.5680819005472462, "SPIKEVAX": 2.7029194172027804, "VAXZEVRIA": 2.1133194974200094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11959.json
new file mode 100644
index 00000000000..98b032cd3c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11959.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1775220133443201, "null": 4.1867030266967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1196.json
index e372d1904c7..7c17c2e0ef3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1196.json
@@ -1 +1 @@
-{"ARAVA": 23.247899823677518, "ATRIPLA": 1.3744424611173565, "CICLOSPORIN": 6.870552093900566, "ENBREL": 9.510019296380248, "STRIBILD": 12.0161605234461}
\ No newline at end of file
+{"ADALIMUMAB": 0.7330320470065015, "ALEMTUZUMAB": 71.37771578358002, "ASPARAGINASE": 11.791158140462096, "BASILIXIMAB": 113.15181663826073, "BUDESONIDE": 10.199630697849, "BUSULFAN": 147.7661858698862, "CARMUSTINE": 25.8132013532908, "CELLCEPT": 34.80095145944165, "CICLOSPORIN": 58.81928044300638, "CYTARABINE": 8.457186047866314, "ECULIZUMAB": 149.3936424243999, "JAKAVI": 4.532120530282789, "METHOTREXATE": 4.768129938048894, "MYCOPHENOLATE": 64.16217618913932, "RUXOLITINIB": 23.62533352555422, "SOLIRIS": 6.924371248208181, "null": 0.1689778516420497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11960.json
new file mode 100644
index 00000000000..c12d274b236
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11960.json
@@ -0,0 +1 @@
+{"null": 1.308269228709178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11961.json
new file mode 100644
index 00000000000..df23252a0e6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11961.json
@@ -0,0 +1 @@
+{"null": 0.5861542665449329}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11962.json
new file mode 100644
index 00000000000..e7feba879f9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11962.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3850308056493402, "IBRANCE": 8.273808372941785, "SUTENT": 2.188502203420137, "null": 1.2423560183357862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11963.json
new file mode 100644
index 00000000000..ed5efc9fb15
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11963.json
@@ -0,0 +1 @@
+{"CASPOFUNGIN": 237.0318399428488, "CYTARABINE": 48.17872143441225, "null": 0.2163481547853288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11964.json
new file mode 100644
index 00000000000..6ddedfa53a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11964.json
@@ -0,0 +1 @@
+{"null": 2.56043921014136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11965.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11965.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11966.json
new file mode 100644
index 00000000000..dacacbf0d5f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11966.json
@@ -0,0 +1 @@
+{"MIDAZOLAM": 56.4552248947429, "null": 1.5975015570171442}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11967.json
new file mode 100644
index 00000000000..d3acc4dcac1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11967.json
@@ -0,0 +1 @@
+{"AFINITOR": 1.0168481846403938, "APIXABAN": 1.2651573065536974, "ARIPIPRAZOLE": 3.7439524528051895, "AVANDIA": 4.319504011342207, "BEDAQUILINE": 19.80169817548116, "BRILIQUE": 6.014842321400651, "BUDESONIDE": 0.9341295279327282, "CLOPIDOGREL": 3.486057858211718, "COMIRNATY": 0.2647670938305795, "CYTARABINE": 1.5799945737167798, "DAPAGLIFLOZIN": 35.48981291633555, "ELIQUIS": 1.425984660517718, "ENALAPRIL": 58.410053902137946, "ENTRESTO": 11.18877834642918, "EXJADE": 1.3667874044271775, "GARDASIL": 0.5518543497791963, "IBUPROFEN": 3.979441477563959, "IRBESARTAN": 10.79322902873088, "KALETRA": 3.0304792734652053, "KEYTRUDA": 0.5243113741618337, "NAGLAZYME": 6.41854196340814, "OLANZAPINE": 1.1212815459909182, "OPSUMIT": 1.1203127284731125, "PANTOPRAZOLE": 4.349160441227806, "SILDENAFIL": 9.716138405049865, "SPIKEVAX": 0.1923720441904587, "TASIGNA": 8.21797017104777, "TOZINAMERAN": 0.2613405116939485, "TRACLEER": 3.259277291880033, "VALSARTAN": 8.21231645732534, "VAXZEVRIA": 0.0330208448805179, "XOLAIR": 1.2716834970871531, "ZOSTAVAX": 2.148305202425133, "ZYPREXA": 0.8555905397758533, "null": 1.7332168884842882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11968.json
new file mode 100644
index 00000000000..b7a2ebdac24
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11968.json
@@ -0,0 +1 @@
+{"null": 1.913393433494604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11969.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11969.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1197.json
index f720f459d96..bda84c119df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1197.json
@@ -1 +1 @@
-{"ARAVA": 2.6304053565746464, "ATRIPLA": 4.20988270138978, "MACI": 25827.71185109847, "XELJANZ": 6.158186333180558}
\ No newline at end of file
+{"DABRAFENIB": 1004.5702561249988, "MEKINIST": 111.68223401325032}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11970.json
new file mode 100644
index 00000000000..01098349077
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11970.json
@@ -0,0 +1 @@
+{"null": 1.2825526105920724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11971.json
new file mode 100644
index 00000000000..ce829ae65c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11971.json
@@ -0,0 +1 @@
+{"BIKTARVY": 25.901010519695184, "COMIRNATY": 3.010336594464003, "SPIKEVAX": 0.9209154063775392, "TOZINAMERAN": 1.0846760252189718, "VAXZEVRIA": 0.5593850988865187, "null": 0.2559831701570337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11972.json
new file mode 100644
index 00000000000..a91f238aa19
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11972.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.9831000632517566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11973.json
new file mode 100644
index 00000000000..d0980475d9f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11973.json
@@ -0,0 +1 @@
+{"AIMOVIG": 2.8300187958511445, "AUBAGIO": 5.021187932670901, "CHAMPIX": 1.5994515437966506, "COMIRNATY": 3.0206612536413493, "CYMBALTA": 1.1928855445919146, "FAMPYRA": 31.552796554408527, "GARDASIL": 0.5244098386462249, "LYRICA": 1.6362917510306174, "PREGABALIN": 3.826842371479175, "REBIF": 30.73996218134699, "SHINGRIX": 4.3689770098445, "SPIKEVAX": 1.425841147452549, "STELARA": 0.6700738615657571, "TOZINAMERAN": 1.525635913251884, "VAXZEVRIA": 1.2652721711964885, "XELJANZ": 0.6760865554080746, "ZOSTAVAX": 6.668228875655582, "null": 0.3523187238466387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11974.json
new file mode 100644
index 00000000000..2ddc906dd7d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11974.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.302712745631972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11975.json
new file mode 100644
index 00000000000..c064b52a5d6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11975.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.392660642429148}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11976.json
new file mode 100644
index 00000000000..703bb677a3a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11976.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.7732359596780058}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11977.json
new file mode 100644
index 00000000000..5c9dbd1710d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11977.json
@@ -0,0 +1 @@
+{"null": 1.8431777657473207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11978.json
new file mode 100644
index 00000000000..404e6d9e632
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11978.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4052958182987569, "ENBREL": 3.8169296896928175, "FASLODEX": 6.557475977970399, "HUMALOG": 15.33742399760898, "IBRANCE": 2.8003998729384065, "LANTUS": 2.5505512330981923, "SIMPONI": 3.36580688381273, "SPIKEVAX": 0.3840205736909903, "TOZINAMERAN": 1.6679696527059682, "VAXZEVRIA": 0.406118937525591, "XELJANZ": 8.09884625291275, "ZOSTAVAX": 10.667538189045263, "null": 0.7142788777415386}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11979.json
new file mode 100644
index 00000000000..1b1e859f6e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11979.json
@@ -0,0 +1 @@
+{"FASENRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1198.json
index 1e752ba33a5..dba21405ba0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1198.json
@@ -1 +1 @@
-{"ATRIPLA": 74.29079661197093, "KALETRA": 3.9853695661094974, "STRIBILD": 39.78471389191874, "TRUVADA": 46.45425171637221, "VIREAD": 19.189644575770068}
\ No newline at end of file
+{"null": 2.583734505428933}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11980.json
new file mode 100644
index 00000000000..ef80608db89
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11980.json
@@ -0,0 +1 @@
+{"METHOTREXATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11981.json
new file mode 100644
index 00000000000..3c70dab6971
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11981.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.352105932839409, "TRODELVY": 210.4750744130611, "null": 0.2689676293541716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11982.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11982.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11983.json
new file mode 100644
index 00000000000..46115b6ca6b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11983.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 4.482552871961701, "BRINTELLIX": 1.875323493981018, "COMIRNATY": 0.6151698282990644, "COSENTYX": 3.138113128319959, "CYMBALTA": 1.7893581785851849, "FENTANYL": 1.4084567255994696, "GARDASIL": 1.4240593856453587, "HUMALOG": 0.7387146225715975, "HUMIRA": 2.299904390281895, "KEPPRA": 1.0825856107318157, "LATUDA": 10.586490390139504, "MMRVAXPRO": 1.4021147119462785, "OLANZAPINE": 1.0113568405714706, "SPIKEVAX": 0.3767480797039196, "SUBOXONE": 1.8133795761846732, "TOZINAMERAN": 0.7205570350391931, "VAXZEVRIA": 0.4680152281466619, "ZYPREXA": 2.063182590581448, "null": 2.624026647772664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11984.json
new file mode 100644
index 00000000000..c7bbe0dda16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11984.json
@@ -0,0 +1 @@
+{"null": 1.2052203392349996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11985.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11985.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11986.json
new file mode 100644
index 00000000000..bbde0d882ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11986.json
@@ -0,0 +1 @@
+{"EFAVIRENZ": 152.24539902521903, "FLUTICASONE": 348.3814931288393, "null": 0.7360513477162183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11987.json
new file mode 100644
index 00000000000..6356727f355
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11987.json
@@ -0,0 +1 @@
+{"COMBIVIR": 67.38625597794434, "KALETRA": 15.563376011020535, "LAMIVUDINE": 52.8840389702044, "PEGASYS": 2.6579682507136004, "SUBOXONE": 6.758648035625473, "null": 1.4735309857922751}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11988.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11988.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11989.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11989.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1199.json
index 50aa46b46a2..321e0795f93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1199.json
@@ -1 +1 @@
-{"ACLASTA": 26.54421966391294, "ANAKINRA": 3.302796236996701, "ARAVA": 1.030970546830037, "ATRIPLA": 57.33276829701274, "EVENITY": 84.08274061974352, "KALETRA": 1.3464215184973771, "STRIBILD": 44.9800487963953, "TRUVADA": 41.5219315712452, "VIREAD": 8.572696541278924}
\ No newline at end of file
+{"null": 1.1010067012107208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11990.json
new file mode 100644
index 00000000000..02f4b5dcd4f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11990.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.2577398646546056, "SPIKEVAX": 10.009676916295998, "null": 0.1132497232935015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11991.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11991.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11992.json
new file mode 100644
index 00000000000..ccc33e7f539
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11992.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 5.658868087956544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11993.json
new file mode 100644
index 00000000000..bc6ecbce732
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11993.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 4.136118034083462, "COMIRNATY": 1.4332637113908908, "DOCETAXEL": 8.995577780153678, "KEYTRUDA": 2.9040463898065627, "LANTUS": 1.8282162482324644, "SPIKEVAX": 0.5297630488855812, "VAXZEVRIA": 0.1238906241248964, "null": 1.1266882572295138}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11994.json
new file mode 100644
index 00000000000..b5ca52a4680
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11994.json
@@ -0,0 +1 @@
+{"APIXABAN": 4.704933921260735, "ARIPIPRAZOLE": 33.04589494189589, "COMIRNATY": 1.902021873178872, "KEYTRUDA": 3.580594670105923, "OLANZAPINE": 3.72592490790784, "SPIKEVAX": 0.2653326539493066, "VAXZEVRIA": 0.108302011763739, "null": 0.7967874522849948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11995.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11995.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11996.json
new file mode 100644
index 00000000000..509240c7708
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11996.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.372928219550427, "VAXZEVRIA": 0.5469443208150532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11997.json
new file mode 100644
index 00000000000..b64f2f89fc2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11997.json
@@ -0,0 +1 @@
+{"ADCIRCA": 6.494352890782109, "ADENURIC": 11.779090954283472, "AIMOVIG": 0.6950435622935414, "ARIPIPRAZOLE": 7.413652940200365, "AVANDIA": 0.5572583056474215, "BRILIQUE": 3.080053992708326, "CLOPIDOGREL": 4.116190685526284, "COMIRNATY": 2.0531824432295034, "CYMBALTA": 0.2457033478742843, "DARZALEX": 2.244771514262742, "DEXAMETHASONE": 0.7372386046841046, "ELIQUIS": 0.7341017415226044, "EMPAGLIFLOZIN": 18.5630518246315, "ENTRESTO": 1.121947970539115, "FENTANYL": 1.84181219794916, "IRBESARTAN": 5.932421160486333, "JARDIANCE": 4.947055899774461, "KEPPRA": 0.4748212951454547, "KEYTRUDA": 4.445705566910278, "OLANZAPINE": 4.912705068373066, "OPDIVO": 2.364477633319907, "OPSUMIT": 0.7465174223900752, "PALIPERIDONE": 33.06369737596907, "PANTOPRAZOLE": 4.379827226792524, "PEGASYS": 0.2164462294141196, "PEMBROLIZUMAB": 2.3391313445131177, "PLAVIX": 1.392589448619595, "PRIVIGEN": 2.335287552624162, "RIVAROXABAN": 10.700892487360433, "SPIKEVAX": 1.111506964688103, "SUTENT": 0.3706500921022743, "TOZINAMERAN": 1.638843121619301, "TRACLEER": 1.2337355744261775, "VAXZEVRIA": 0.319963770360831, "XOLAIR": 0.7478990582560779, "null": 0.6830692002799044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11998.json
new file mode 100644
index 00000000000..8c07a6828ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11998.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 40.31283568566023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11999.json
new file mode 100644
index 00000000000..c865484fa95
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/11999.json
@@ -0,0 +1 @@
+{"null": 2.415539241758726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12.json
index 11434a8b865..d7aa0f16ba9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12.json
@@ -1 +1 @@
-{"CASPOFUNGIN": 73.40130016887204, "CYTARABINE": 10.285658777435517, "LANTUS": 2.8007261832566064, "PEGASYS": 2.394671059154865, "SUTENT": 3.7622424389805738}
\ No newline at end of file
+{"AFINITOR": 499.4178760842281}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/120.json
index 2dd4324a506..40962a902e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/120.json
@@ -1 +1 @@
-{"COMIRNATY": 3.454785090503722}
\ No newline at end of file
+{"COMIRNATY": 1.4945175306440042, "VAXZEVRIA": 4.101578473109125}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1200.json
index 0b2926aa165..9cb17350bec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1200.json
@@ -1 +1 @@
-{"ANAKINRA": 1.55759936635475, "ATRIPLA": 78.92184879562389, "DESCOVY": 2.229346078968495, "EVENITY": 1.9410009840378415, "EVISTA": 3.216952570509279, "GENVOYA": 1.3261129985086386, "HEPSERA": 1.4482363283000208, "KALETRA": 5.301092496891122, "STRIBILD": 41.367314904971614, "TRUVADA": 53.94310226682398, "VIREAD": 17.818182053264678}
\ No newline at end of file
+{"CICLOSPORIN": 100.51485370394995}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12000.json
new file mode 100644
index 00000000000..4d506717c0a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12000.json
@@ -0,0 +1 @@
+{"ALISKIREN": 426.2261213153745, "null": 2.443084458239189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12001.json
new file mode 100644
index 00000000000..739475634c1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12001.json
@@ -0,0 +1 @@
+{"HUMAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12002.json
new file mode 100644
index 00000000000..e2c2dd3ab35
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12002.json
@@ -0,0 +1 @@
+{"null": 7.505399154951763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12003.json
new file mode 100644
index 00000000000..a8362269797
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12003.json
@@ -0,0 +1 @@
+{"null": 7.456555147927114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12004.json
new file mode 100644
index 00000000000..361cf46e9a7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12004.json
@@ -0,0 +1 @@
+{"FENTANYL": 12.72689835518342, "null": 6.071161996521442}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12005.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12005.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12006.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12006.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12007.json
new file mode 100644
index 00000000000..1af4edfcf37
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12007.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 1.085131726616941, "ARAVA": 15.270430978615195, "CIMZIA": 16.8391215949838, "COSENTYX": 4.116555711509889, "PEGASYS": 2.172627861645715, "SIMPONI": 8.508604334909261, "STELARA": 48.61293477738767, "XELJANZ": 4.125238400753922, "null": 0.2568907446173964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12008.json
new file mode 100644
index 00000000000..b0fe8778947
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12008.json
@@ -0,0 +1 @@
+{"LAMIVUDINE": 495.5222310372432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12009.json
new file mode 100644
index 00000000000..ef4f06ff431
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12009.json
@@ -0,0 +1 @@
+{"EMTRICITABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1201.json
index 4b431dd6210..e944bd40804 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1201.json
@@ -1 +1 @@
-{"ABATACEPT": 20.21140819726369, "ADALIMUMAB": 22.676199217951705, "ANAKINRA": 86.04486263980219}
\ No newline at end of file
+{"COMIRNATY": 1.9906184300331693, "SPIKEVAX": 7.585121110168986, "TOZINAMERAN": 1.8185978637649745, "VAXZEVRIA": 2.1488652000772763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12010.json
new file mode 100644
index 00000000000..ca55776e147
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12010.json
@@ -0,0 +1 @@
+{"AMINOSALICYLIC": 42.360349954131486, "DEXAMETHASONE": 25.77388465790264, "null": 2.4441773942446083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12011.json
new file mode 100644
index 00000000000..ed81570d1ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12011.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.6107774527864551, "ADALIMUMAB": 0.3773997418744447, "AFINITOR": 1.588463460193103, "ALEMTUZUMAB": 1.7563992206243235, "AMIKACIN": 10.360097953491495, "AMINOSALICYLIC": 30.57288789121698, "ARAVA": 0.9603458371659552, "ATRIPLA": 0.1135970690893819, "AUBAGIO": 0.7732787540504108, "AZATHIOPRINE": 2.538401420806302, "BEDAQUILINE": 79.38512672191074, "BENLYSTA": 2.179204434339044, "BIKTARVY": 6.468261637296992, "BUDESONIDE": 1.5622433246048462, "CELLCEPT": 3.943711860328162, "CICLOSPORIN": 4.481414876562063, "CIMZIA": 6.661691757930691, "COMBIVIR": 7.817686107574019, "COMIRNATY": 0.0282095803103692, "COSENTYX": 4.600115367144682, "CYTARABINE": 0.9810595955231696, "DELAMANID": 31.188292699759064, "DELTYBA": 51.57525033759398, "DEXAMETHASONE": 1.547603557433867, "EFAVIRENZ": 19.47476171192955, "ELIQUIS": 0.3194387150211867, "EMTRICITABINE": 10.76878032218702, "ENBREL": 2.727340379548888, "ENTYVIO": 2.8264800688785736, "EPIVIR": 14.217524984773917, "FORSTEO": 0.8682747510343938, "GENVOYA": 7.518712043146201, "HUMALOG": 0.3584698540849077, "HUMIRA": 5.358199747716487, "INCIVO": 1.5690592295453385, "INFLIXIMAB": 9.124205567711488, "JAKAVI": 20.161597609222373, "KALETRA": 4.129770877628552, "KEYTRUDA": 0.5655467693811929, "LAMIVUDINE": 18.855335508012224, "LANTUS": 0.2671301099218789, "LEFLUNOMIDE": 6.586947556867925, "LEMTRADA": 2.017288046519175, "LEVOFLOXACIN": 3.662527428515875, "METFORMIN": 20.661724594586023, "METHOTREXATE": 4.932037674318972, "MYCOPHENOLATE": 4.083420163765368, "NEXAVAR": 0.710850627592428, "NOT": 4.251922774232854, "PEGASYS": 2.311289699114206, "PEGINTERFERON": 3.5212570658391678, "PEGINTRON": 2.0771039166099965, "REMICADE": 8.442488129413855, "RINVOQ": 4.8639678234905, "ROACTEMRA": 5.429770079119413, "RUXOLITINIB": 10.009631931355113, "SIMPONI": 12.65540919227754, "SKYRIZI": 6.911136707464373, "SOLIRIS": 1.2382042912622997, "SPRYCEL": 1.39341849609763, "STELARA": 8.72908644899514, "SUTENT": 0.3202426902475538, "TACROLIMUS": 7.325966222814844, "TIVICAY": 12.91509444304382, "TREMFYA": 10.617560339410833, "VFEND": 1.446186789844233, "XELJANZ": 6.059747819163714, "XOLAIR": 0.5621569476864688, "null": 0.6091658597967355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12012.json
new file mode 100644
index 00000000000..558aecb135c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12012.json
@@ -0,0 +1 @@
+{"null": 0.6102101117711721}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12013.json
new file mode 100644
index 00000000000..55c409669be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12013.json
@@ -0,0 +1 @@
+{"STELARA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12014.json
new file mode 100644
index 00000000000..d9fcec16c57
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12014.json
@@ -0,0 +1 @@
+{"FUZEON": 7613.25089238314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12015.json
new file mode 100644
index 00000000000..0de144d6ec5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12015.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": 43.131077515634594, "EFAVIRENZ": 148.4682050411295, "null": 0.3048386302386422}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12016.json
new file mode 100644
index 00000000000..26fa2778482
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12016.json
@@ -0,0 +1 @@
+{"BEDAQUILINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12017.json
new file mode 100644
index 00000000000..8aef6fb3ad8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12017.json
@@ -0,0 +1 @@
+{"PEGASYS": 4.891064107128184, "PEGINTRON": 10.374034978172435, "SIMPONI": 36.93286330474748, "null": 0.5309648439136055}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12018.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12018.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12019.json
new file mode 100644
index 00000000000..4a124daee88
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12019.json
@@ -0,0 +1 @@
+{"null": 1.159683279053483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1202.json
index 01954154d72..e0b7b72a73b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1202.json
@@ -1 +1 @@
-{"null": 2.194682658719877}
\ No newline at end of file
+{"null": 0.4335501018639234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12020.json
new file mode 100644
index 00000000000..a0aefd2dde4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12020.json
@@ -0,0 +1 @@
+{"AFINITOR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12021.json
new file mode 100644
index 00000000000..52da8050d3d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12021.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.3229162528805047, "ADALIMUMAB": 0.5741084740960516, "ADENURIC": 7.12079174613846, "AERIUS": 2.188799293986053, "ALEMTUZUMAB": 1.3322930112793487, "ALIMTA": 8.117682543728291, "APROVEL": 4.4593622910221145, "ARAVA": 0.0843864402678738, "ARIPIPRAZOLE": 0.7869786746572265, "ATAZANAVIR": 5.014907065980238, "ATRIPLA": 0.5481936914609008, "AVASTIN": 0.7672852067012853, "AXITINIB": 6.646010823736642, "AZATHIOPRINE": 2.1232875788455337, "BASILIXIMAB": 18.187241978353956, "BIKTARVY": 1.3041626828172228, "BLINATUMOMAB": 8.279905589264084, "BRAFTOVI": 1.57507742489057, "BUDESONIDE": 0.3065754612133645, "BUSULFAN": 3.4600422468209007, "CELECOXIB": 4.84254576135494, "CELLCEPT": 1.69780730707617, "CICLOSPORIN": 2.123005516529866, "CIMZIA": 0.1937962514908136, "COMIRNATY": 0.0642917353996447, "CRIXIVAN": 9.112639918945137, "CUBICIN": 9.117199007140034, "DEXAMETHASONE": 0.6622151269267798, "EFAVIRENZ": 4.816934084225573, "ELIQUIS": 0.3343813087182616, "ENTYVIO": 5.081694462987753, "ESOMEPRAZOLE": 10.228406343167066, "EXFORGE": 0.7426761441712639, "EXJADE": 0.7546174147616039, "FEBUXOSTAT": 8.222750106862218, "FORXIGA": 1.2169397355325415, "GANCICLOVIR": 3.3693175426411206, "GARDASIL": 0.2051385181706356, "HEPSERA": 6.974678317951045, "HUMIRA": 0.6800977952815034, "IBUPROFEN": 4.036342410038358, "INLYTA": 2.1842972752489462, "IPILIMUMAB": 11.279064762142358, "IRBESARTAN": 2.857486746749439, "ISENTRESS": 1.9318491693324449, "JANUMET": 0.4856011785924164, "JANUVIA": 0.9210888105876462, "JARDIANCE": 0.5231758905763045, "KALETRA": 1.543007872947615, "KEPPRA": 0.6576905016591155, "KEYTRUDA": 10.747595778394777, "KIVEXA": 13.321725348363682, "LEVETIRACETAM": 4.359245735523142, "LEVOFLOXACIN": 5.313961870764327, "LYRICA": 0.6323051833502807, "MEKINIST": 2.204870821297397, "MICARDIS": 1.457463717842097, "MYCOPHENOLATE": 2.039295664317062, "NIVOLUMAB": 12.246605952736468, "NORVIR": 4.546324602029553, "OPDIVO": 9.04539935680851, "PANTOPRAZOLE": 8.86462339544968, "PEGASYS": 0.1694830527367154, "PEGINTRON": 0.6150639393341877, "PEMBROLIZUMAB": 15.03106955936286, "PEMETREXED": 7.006932152896293, "PLAVIX": 0.7413504861913637, "SIMPONI": 0.8275168881244609, "SPIKEVAX": 0.0498748857031724, "SUTENT": 0.206638499381031, "TAMIFLU": 0.9757048758323298, "TENOFOVIR": 5.814511798411333, "TOZINAMERAN": 0.0967161530655483, "TRUVADA": 1.4282942306787691, "VAXZEVRIA": 0.028668083778964, "VEDOLIZUMAB": 12.044150533428796, "VICTOZA": 1.0815282163636857, "VIREAD": 6.433778344184137, "ZONISAMIDE": 16.623826372446818, "null": 2.3197545677604348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12022.json
new file mode 100644
index 00000000000..fd1ece4af8c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12022.json
@@ -0,0 +1 @@
+{"null": 1.3270481012813211}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12023.json
new file mode 100644
index 00000000000..ca52cf48e8e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12023.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 51.05890673166939, "null": 0.1829856164494409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12024.json
new file mode 100644
index 00000000000..98e857e87e7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12024.json
@@ -0,0 +1 @@
+{"null": 0.1743982470966958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12025.json
new file mode 100644
index 00000000000..c7afda292c8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12025.json
@@ -0,0 +1 @@
+{"NEXAVAR": 126.33581840400608, "null": 0.2280182226993714}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12026.json
new file mode 100644
index 00000000000..594f009f0ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12026.json
@@ -0,0 +1 @@
+{"KEPPRA": 6.790339793507255, "NUCALA": 12.910865108096008, "VOTRIENT": 45.44968984877484, "null": 1.4492274413116284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12027.json
new file mode 100644
index 00000000000..d7914affba3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12027.json
@@ -0,0 +1 @@
+{"FASLODEX": 39.262447548276285, "null": 0.3969928511958395}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12028.json
new file mode 100644
index 00000000000..7f778221132
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12028.json
@@ -0,0 +1 @@
+{"AFINITOR": 2.132727463996519, "AVASTIN": 17.57927710369939, "BRAFTOVI": 7.010344678232548, "CABOMETYX": 8.39564204950474, "CLOPIDOGREL": 6.098697034186054, "ELIQUIS": 8.454189622179612, "IBRANCE": 2.2087708076208314, "INLYTA": 4.658695431419001, "KEYTRUDA": 7.391472663156597, "LENVIMA": 84.89722879375826, "NEXAVAR": 20.554212242039533, "OPDIVO": 7.962916417110066, "PLAVIX": 2.688393366943665, "STIVARGA": 16.490273241596334, "SUTENT": 17.85792949201236, "VOTRIENT": 9.312143106967412, "null": 0.4500391981368583}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12029.json
new file mode 100644
index 00000000000..1983ca9fdbd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12029.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 100.92984645958352, "PEMBROLIZUMAB": 286.3438936491698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1203.json
index 444a4c44a0a..180fad3d7cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1203.json
@@ -1 +1 @@
-{"ABRAXANE": 10.893484085997594, "ATRIPLA": 28.906023333376645, "AZATHIOPRINE": 1.0101969294246411, "BONVIVA": 4.904500151741326, "BYDUREON": 1.045702603082918, "DARZALEX": 1.5183756040725054, "EMTRICITABINE": 4.120061661074426, "ENBREL": 1.4686654210493388, "EVENITY": 3.775575725507248, "EVISTA": 4.816449972754821, "FASLODEX": 1.8533089031530277, "FORSTEO": 3.1646359767512524, "FULVESTRANT": 4.578510109014138, "HUMALOG": 1.0416546292574165, "HYDROCORTISONE": 4.187236907389356, "IBRANCE": 3.566690824939559, "INLYTA": 1.0010597026248207, "JANUVIA": 1.040702699799619, "LYRICA": 1.3651236997663911, "RITUXIMAB": 2.18311665541804, "STRIBILD": 9.567419231356164, "TESTOSTERONE": 7.145259602703311, "THALIDOMIDE": 4.40870021513675, "TRUVADA": 13.430547128528756, "VIREAD": 8.314844943384319, "VORICONAZOLE": 1.8442272256760976, "XELJANZ": 3.235768140362503, "ZOMETA": 41.80690296883919, "ZOSTAVAX": 1.5817854404646587}
\ No newline at end of file
+{"AZACITIDINE": 97.91668952419596, "ENTYVIO": 102.83624474216896, "null": 0.5485802861603059}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12030.json
new file mode 100644
index 00000000000..0c61bae8406
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12030.json
@@ -0,0 +1 @@
+{"JANUMET": 72.68453382448082, "NEXAVAR": 15.693968202299128, "null": 0.5798203872283928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12031.json
new file mode 100644
index 00000000000..b0022b9967b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12031.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 10.972282079807687, "AVASTIN": 2.141808539161988, "AXICABTAGENE": 55.43007643811781, "AZACITIDINE": 72.42978168997577, "BEVACIZUMAB": 3.108155478611537, "BLINCYTO": 42.451017519193314, "BORTEZOMIB": 25.30212047094461, "BRAFTOVI": 5.508474163760502, "CARFILZOMIB": 36.26349571983143, "CYTARABINE": 14.06014717213332, "DARZALEX": 17.801571727913366, "DEXAMETHASONE": 10.698723031718824, "DOCETAXEL": 3.305037123296783, "DOXORUBICIN": 15.637144222325285, "FASTURTEC": 52.99487645992284, "GAZYVARO": 111.77361695970691, "HERCEPTIN": 4.192336474724116, "IBRUTINIB": 31.630603538295382, "IMBRUVICA": 22.43692958919648, "JAKAVI": 2.9970371283805437, "JEVTANA": 8.03179958758369, "KEYTRUDA": 3.019872986768747, "KYMRIAH": 10.239030383835916, "KYPROLIS": 72.67557157412313, "LENVIMA": 22.158735252069334, "MABTHERA": 5.392357082724299, "MEKINIST": 1.505136816424544, "METHOTREXATE": 2.829697838140508, "NEXAVAR": 4.022796509248779, "OBINUTUZUMAB": 105.11442352676312, "OPDIVO": 4.7530033151256585, "POTELIGEO": 30.5488812903053, "RASBURICASE": 142.40462717353353, "RITUXIMAB": 20.245185427883733, "RIXATHON": 15.228527141675633, "SORAFENIB": 15.731632606322991, "SPRYCEL": 3.264092860971662, "SUTENT": 3.595700422899239, "TASIGNA": 1.9368196824889845, "THALIDOMIDE": 8.188848339258541, "TISAGENLECLEUCEL": 45.50688407212719, "VELCADE": 22.633976958755504, "VENCLYXTO": 151.95913557135515, "VENETOCLAX": 219.76394475950687, "VIDAZA": 90.17712433636484, "VOTRIENT": 1.574139698788799, "null": 0.651906769181965}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12032.json
new file mode 100644
index 00000000000..1668bd654da
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12032.json
@@ -0,0 +1 @@
+{"FASLODEX": 58.22577495888871, "IBRANCE": 30.668097765887072, "null": 0.2116985590593785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12033.json
new file mode 100644
index 00000000000..5a94911123c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12033.json
@@ -0,0 +1 @@
+{"ABEMACICLIB": 96.50616766760608, "ABRAXANE": 50.55661377691028, "AFINITOR": 20.6044202337824, "AVASTIN": 5.215905485521831, "BEVACIZUMAB": 5.822122055280207, "CAPECITABINE": 20.707129199067424, "COMIRNATY": 0.0849410714189763, "DENOSUMAB": 20.024837824377897, "EVEROLIMUS": 19.677953169321498, "FASLODEX": 110.9066845384365, "FULVESTRANT": 54.699471354369024, "IBRANCE": 34.73127615964564, "ICLUSIG": 6.6734482241142175, "IRESSA": 11.504208316702814, "KEYTRUDA": 3.551526849782026, "KISQALI": 25.20782291049756, "LYNPARZA": 47.97801204901999, "NEXAVAR": 5.3202378299742366, "PEGASYS": 0.7853838017321886, "RIBOCICLIB": 18.321001091922437, "RUBRACA": 27.72934008417512, "STIVARGA": 16.638654375736774, "TAGRISSO": 11.272312365499168, "null": 0.2646790218256608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12034.json
new file mode 100644
index 00000000000..c386422e570
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12034.json
@@ -0,0 +1 @@
+{"AFINITOR": 8.065671243659974, "AVASTIN": 21.409158737716627, "BEVACIZUMAB": 59.7994941630424, "CABOMETYX": 19.208303575720848, "EVEROLIMUS": 96.702265388255, "KEYTRUDA": 15.666612343451034, "NEXAVAR": 22.585449187161284, "STIVARGA": 18.155347248931783, "SUTENT": 4.978336043355714, "VOTRIENT": 12.057308322147298, "null": 0.3920386842354775}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12035.json
new file mode 100644
index 00000000000..1be6642a372
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12035.json
@@ -0,0 +1 @@
+{"IBRANCE": 9.45218343052788, "KEYTRUDA": 6.875913257159721, "STIVARGA": 14.553877713781176, "SUTENT": 23.99259038738648, "VOTRIENT": 30.132106336247368, "null": 0.4196553986914231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12036.json
new file mode 100644
index 00000000000..917b1017067
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12036.json
@@ -0,0 +1 @@
+{"AVASTIN": 105.67136921006804, "null": 0.6347991971088278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12037.json
new file mode 100644
index 00000000000..fd0151db097
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12037.json
@@ -0,0 +1 @@
+{"PEMBROLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12038.json
new file mode 100644
index 00000000000..c7dbb84a6f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12038.json
@@ -0,0 +1 @@
+{"IPILIMUMAB": 61.98276320803039, "KEYTRUDA": 81.37588099223142, "OPDIVO": 62.74309221286461, "PEMBROLIZUMAB": 184.117515946807, "TEMOZOLOMIDE": 488.9504675403912, "null": 0.2062546163966717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12039.json
new file mode 100644
index 00000000000..4d574a5dec5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12039.json
@@ -0,0 +1 @@
+{"LENVIMA": 53.60569918896044, "NEXAVAR": 59.175492977968176, "SUTENT": 26.250276919291267, "null": 0.3494221457570424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1204.json
index ce41720afbd..0918d6380d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1204.json
@@ -1 +1 @@
-{"ABACAVIR": 4.959304350083734, "ABATACEPT": 57.41947948371461, "ADALIMUMAB": 19.76518918226552, "AMINOSALICYLIC": 4.016127326760983, "ANAKINRA": 4.033779177202423, "ARAVA": 29.95929272242476, "AZATHIOPRINE": 5.750505770324966, "BOTULINUM": 9.27105165551999, "CELECOXIB": 4.877755447253628, "CELLCEPT": 1.6857127491402897, "CERTOLIZUMAB": 55.72122966408984, "CICLOSPORIN": 3.907270422327623, "CIMZIA": 2.39266632837647, "COSENTYX": 4.228706810280589, "ENBREL": 12.31566512792174, "HUMIRA": 1.4092764869511991, "LEFLUNOMIDE": 10.50742902563494, "METHOTREXATE": 1.3822505914489591, "XELJANZ": 1.2717745825826503}
\ No newline at end of file
+{"ASPARAGINASE": 276.1900724893627, "null": 1.0426276596056734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12040.json
new file mode 100644
index 00000000000..3e7d1dab1e4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12040.json
@@ -0,0 +1 @@
+{"NEXAVAR": 148.05952665516938}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12041.json
new file mode 100644
index 00000000000..11bed39d3d0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12041.json
@@ -0,0 +1 @@
+{"CHAMPIX": 4.359874933571327, "COMIRNATY": 0.7180335901433479, "GARDASIL": 1.9950079091622168, "PEGINTRON": 3.1594182052319075, "SPIKEVAX": 1.2496129348310838, "TOZINAMERAN": 3.355527524480604, "VAXZEVRIA": 0.3722957363865791, "VIAGRA": 6.230160285141155, "null": 1.1864843816343746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12042.json
new file mode 100644
index 00000000000..fd1ece4af8c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12042.json
@@ -0,0 +1 @@
+{"null": 1.3270481012813211}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12043.json
new file mode 100644
index 00000000000..7e425e6cdb3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12043.json
@@ -0,0 +1 @@
+{"CIMZIA": 17.94243406781907, "KEPPRA": 24.059327242550214, "REYATAZ": 127.26107473158744, "null": 0.7525142517694742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12044.json
new file mode 100644
index 00000000000..7f8a6bfc8fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12044.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6538955299520138, "null": 1.597741621533317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12045.json
new file mode 100644
index 00000000000..0a73fe35559
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12045.json
@@ -0,0 +1 @@
+{"MMRVAXPRO": 60.92190509399489, "null": 0.8572740378047333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12046.json
new file mode 100644
index 00000000000..7e000b2a3be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12046.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2269432991018034, "PEGASYS": 2.180159899447024, "SIMPONI": 5.250037202821727, "VAXZEVRIA": 0.2198909269378156, "null": 1.0981108201540493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12047.json
new file mode 100644
index 00000000000..2d25fea8fb9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12047.json
@@ -0,0 +1 @@
+{"null": 2.212712716221833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12048.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12048.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12049.json
new file mode 100644
index 00000000000..375595ecebc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12049.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.6890068973404477, "ASPARAGINASE": 2.793739560365604, "ATAZANAVIR": 3.222750840698257, "AXITINIB": 5.43548937984069, "BIKTARVY": 1.676784032469055, "BYETTA": 1.9170530773638932, "CELLCEPT": 1.535948919341537, "CHAMPIX": 1.0749112065935456, "CICLOSPORIN": 0.4435115377721323, "CIMZIA": 0.4299841265097092, "COMIRNATY": 0.4829672103816044, "CRIXIVAN": 4.500700291366508, "DEXAMETHASONE": 0.7496784713818686, "FORXIGA": 1.2776128890854173, "GARDASIL": 3.632634075617855, "HUMALOG": 1.3048197102056234, "HUMIRA": 2.6063099577434405, "INFANRIX": 11.772646214845746, "INLYTA": 4.835605421252635, "INSULIN": 3.421556984230567, "INTRONA": 11.643094586855527, "IPILIMUMAB": 39.60417912390341, "JANUMET": 1.002309926352613, "JANUVIA": 1.6048051490983208, "JARDIANCE": 1.707087589161717, "KEYTRUDA": 34.40994460448309, "LANTUS": 0.829924763036475, "LEMTRADA": 2.6795799123452078, "LEVEMIR": 1.7229322009910266, "LIBTAYO": 15.369091241456855, "MMRVAXPRO": 1.068878691712018, "NIMENRIX": 2.885338219304841, "NORVIR": 3.2835210247272197, "OLANZAPINE": 2.2963295938062327, "OPDIVO": 21.305147466049306, "PEGASYS": 5.593327030678427, "PEGINTERFERON": 7.587471402362171, "PEGINTRON": 21.897156254167225, "PEMBROLIZUMAB": 29.25924766727108, "RIBAVIRIN": 3.659968100447061, "SOMATROPIN": 7.415810809777687, "SPIKEVAX": 0.1975405493968696, "TOZINAMERAN": 0.4697803570217163, "VAXZEVRIA": 0.1057160178058093, "XELJANZ": 0.4629363796606889, "XOLAIR": 0.6796452667732205, "ZOSTAVAX": 0.4245951592403927, "ZYPREXA": 14.301828932237015, "null": 0.4271734357205393}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1205.json
index 6dfed37c5c0..22d058b4386 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1205.json
@@ -1 +1 @@
-{"FORSTEO": 34.85181838608185}
\ No newline at end of file
+{"ABATACEPT": 0.4896507124379935, "ADALIMUMAB": 11.189595500143756, "ANAKINRA": 2.0396014735908925, "APIDRA": 1.6778090430098884, "ARAVA": 0.4399884905810353, "ATRIPLA": 0.403843538141927, "AUBAGIO": 2.950170363660659, "BENLYSTA": 1.398430749705812, "BYETTA": 1.6076254233064486, "CIMZIA": 1.3938460089952145, "COMIRNATY": 0.0611406944346042, "COSENTYX": 1.0957826051369597, "CYMBALTA": 1.2451137580449454, "ELIQUIS": 4.281680625903702, "ENBREL": 1.084346884467556, "ENTYVIO": 1.3442723128128986, "FASLODEX": 1.7466316070968606, "FIRDAPSE": 3.96975168885958, "FORSTEO": 1.4227359539859954, "HUMALOG": 3.32591294201659, "HUMIRA": 0.9683889539302212, "IBRANCE": 2.053156699461502, "INLYTA": 1.650271460084758, "INSULIN": 1.3584247890141392, "JANUMET": 0.9704434547838828, "JANUVIA": 0.8723735009330342, "KEPPRA": 0.4177811057411237, "LANTUS": 5.18016305207393, "LYRICA": 10.104154784621764, "NUCALA": 0.7943507720593159, "SIMPONI": 1.920393786258268, "SPRYCEL": 2.271186757345953, "STELARA": 0.5862405442180214, "SUBOXONE": 4.938935903990725, "SUTENT": 0.8233440931334886, "TOVIAZ": 4.491182956468194, "TOZINAMERAN": 0.2855342180011784, "TRULICITY": 2.1226926059458373, "TRUVADA": 0.4569781642497624, "VAXZEVRIA": 0.0216603491792927, "VIAGRA": 16.732121240186682, "XELJANZ": 4.741366052569219, "XTANDI": 1.4607035611018822, "XYREM": 8.387743550887034, "ZOSTAVAX": 2.8643734347418857, "null": 1.289062633870048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12050.json
new file mode 100644
index 00000000000..796e6f23fc0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12050.json
@@ -0,0 +1 @@
+{"null": 2.039075616916378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12051.json
new file mode 100644
index 00000000000..a7d542128b3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12051.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.8780880141275603, "ABATACEPT": 2.12894227095542, "ABILIFY": 2.075872705993881, "ACLIDINIUM": 19.028015269109563, "ADALIMUMAB": 4.104228939743751, "AFINITOR": 1.2468592504738298, "AGOMELATINE": 20.76083486774135, "AMINOSALICYLIC": 1.5196612775782252, "APREMILAST": 1.4194942954694634, "APROVEL": 1.6311670462857202, "ARAVA": 4.9286850610023984, "ARIPIPRAZOLE": 1.451898939428297, "ASPARAGINASE": 1.3043531937803725, "ATRIPLA": 0.0934135156346046, "AUBAGIO": 0.5671746326588072, "AVANDIA": 0.3249370748886896, "AVASTIN": 1.2604341269834245, "AZATHIOPRINE": 0.6872934635940562, "BIKTARVY": 1.075863074398148, "BUDESONIDE": 13.391609187452982, "BYDUREON": 4.778242722900389, "BYETTA": 0.6632402475849427, "CANAGLIFLOZIN": 85.5170368402329, "CELLCEPT": 0.6775326709621871, "CHAMPIX": 0.9446124298338132, "CICLOSPORIN": 0.4778975920496331, "CIMZIA": 2.716970707274378, "CLOPIDOGREL": 1.8484087069502857, "COAPROVEL": 4.668571381059262, "COMIRNATY": 0.107917579086726, "COSENTYX": 2.327116348932031, "CYMBALTA": 0.4768261583532845, "CYTARABINE": 0.4845232688723904, "DAPAGLIFLOZIN": 4.25039460288018, "DARUNAVIR": 3.7810967937569946, "DEXAMETHASONE": 0.4205131775662404, "ELIQUIS": 0.4791384230339283, "EMPAGLIFLOZIN": 2.287267907190837, "ENBREL": 0.6613651870921489, "ENTRESTO": 1.7769271525905213, "ENTYVIO": 0.5548498609240763, "EXFORGE": 3.255823184513652, "FASLODEX": 1.1221419701144992, "FORXIGA": 2.875536110256487, "HARVONI": 0.8813096032941634, "HUMALOG": 0.5153506863826413, "HUMIRA": 4.814065099344285, "IBRANCE": 0.3452558187576475, "ICLUSIG": 1.1541016928068315, "IMATINIB": 3.762850403724652, "INVOKANA": 10.16238964797084, "IRBESARTAN": 1.9933317786456493, "JANUMET": 2.1287515924101448, "JANUVIA": 2.431855441583918, "JARDIANCE": 0.8942556321889058, "KALETRA": 1.180346349835761, "KEPPRA": 0.2900210163866414, "KEYTRUDA": 1.5192389646201978, "LANTUS": 0.4912607141765598, "LATUDA": 1.3192159590723085, "LEFLUNOMIDE": 1.872548213165136, "LYRICA": 2.122791008798918, "METFORMIN": 13.024930574956072, "METHOTREXATE": 0.3136611788580349, "NUCALA": 0.9819588352914332, "OLANZAPINE": 3.0060096751705485, "OMALIZUMAB": 2.241364770904635, "ONGLYZA": 6.253683177396747, "OPDIVO": 0.6765988047398003, "PASIREOTIDE": 23.623451677332252, "PEGASYS": 0.4666181760099719, "PEGINTRON": 0.5696571474656291, "PIOGLITAZONE": 80.67181806877197, "PLAVIX": 0.4182058975302226, "RIBAVIRIN": 0.7712231896375247, "RITUXIMAB": 0.9949111791931704, "SIMPONI": 0.7907488471353394, "SOMATROPIN": 6.847951891042719, "SPIKEVAX": 0.0535039901020255, "SPIRONOLACTONE": 2.372373180506174, "STELARA": 1.1973460996172467, "SUTENT": 0.2081738804422271, "TASIGNA": 2.288853812564261, "TOVIAZ": 1.0667887479487146, "TOZINAMERAN": 0.1223270284352687, "TRELEGY": 0.5669570202961364, "TREMFYA": 1.045877422146078, "TRULICITY": 0.5206821475798573, "VAXZEVRIA": 0.0320679353570442, "VIAGRA": 3.30274636041995, "XELJANZ": 0.7837001489503467, "XOLAIR": 0.8828152181078106, "ZOSTAVAX": 6.1911343991044845, "ZYPREXA": 34.115576957815925, "null": 0.920314893087953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12052.json
new file mode 100644
index 00000000000..08c78f34384
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12052.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 128.54952425366668, "THALIDOMIDE": 200.82207246801983, "null": 2.1956295684010647}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12053.json
new file mode 100644
index 00000000000..e56ebcac52f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12053.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.8917646311019487, "APIDRA": 3.531602693577246, "BRIDION": 29.984702520448167, "CHLORHEXIDINE": 3.2516574980273902, "COMIRNATY": 0.4394508781198479, "COSENTYX": 0.9528966397490044, "DEXAMETHASONE": 7.258241818178921, "ENOXAPARIN": 4.014915444221647, "FENTANYL": 2.8204027551388826, "HUMALOG": 0.8340142771733309, "INSULIN": 5.943672061890271, "LEVOFLOXACIN": 9.037093802536065, "MIDAZOLAM": 7.417708927828644, "OMALIZUMAB": 1.420820728160806, "SPIKEVAX": 0.1364811743656855, "SUFENTANIL": 50.08235675337304, "XOLAIR": 4.032933074165289, "null": 4.3662480762222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12054.json
new file mode 100644
index 00000000000..979462817b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12054.json
@@ -0,0 +1 @@
+{"null": 3.888684653270179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12055.json
new file mode 100644
index 00000000000..4280f8d142e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12055.json
@@ -0,0 +1 @@
+{"APIDRA": 47.49188775263992, "COMIRNATY": 0.2625123773187857, "GARDASIL": 4.682837326379925, "INSULIN": 21.87533758378331, "MENVEO": 42.5449656612914, "VAXZEVRIA": 0.2704168072898596, "XOLAIR": 9.123314363409628, "null": 0.9922161540177048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12056.json
new file mode 100644
index 00000000000..bb45d25257f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12056.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 53.41389673977547, "ZOSTAVAX": 47.19368687575167, "null": 0.3500787521904634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12057.json
new file mode 100644
index 00000000000..eedc17416be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12057.json
@@ -0,0 +1 @@
+{"ACTRAPID": 35.18247295899008, "ADALIMUMAB": 0.433543827090151, "ANAKINRA": 14.761457461393348, "APIDRA": 2.6956169732511013, "BUDESONIDE": 1.3826938263983457, "COMIRNATY": 0.2632045417390337, "ENOXAPARIN": 11.178845643456992, "IBUPROFEN": 4.544151374555248, "LIXIANA": 11.464208883399063, "SPIKEVAX": 0.723766225844821, "TOZINAMERAN": 0.412761828562682, "VAXZEVRIA": 0.1105292158202865, "XOLAIR": 1.6990391967538727, "null": 3.2774233478091515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12058.json
new file mode 100644
index 00000000000..b9c3920ef09
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12058.json
@@ -0,0 +1 @@
+{"DAPAGLIFLOZIN": 419.682493202819, "SILDENAFIL": 46.688622161568986, "ZOSTAVAX": 56.270322763354415, "null": 0.5639718541412485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12059.json
new file mode 100644
index 00000000000..ab9cd5d18ef
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12059.json
@@ -0,0 +1 @@
+{"null": 1.222371341795713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1206.json
index 8d2ce0bb4d4..e0fc0e4c2c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1206.json
@@ -1 +1 @@
-{"ATRIPLA": 14.614271483527272}
\ No newline at end of file
+{"ABATACEPT": 25.35943514537494, "ADALIMUMAB": 20.97463279111221, "AIMOVIG": 7.09043744963268, "APREMILAST": 18.11018938569901, "ARAVA": 5.941367738227746, "ATRIPLA": 0.308705482827076, "BENLYSTA": 1.5008604812547286, "BUPRENORPHINE": 14.290465250715032, "BYETTA": 1.2666176428089235, "CIMZIA": 2.1210293469977315, "CLOPIDOGREL": 0.7324953725217543, "COMIRNATY": 0.0207064030363066, "COSENTYX": 0.4975697371602551, "CYMBALTA": 0.7096037443376042, "ELIQUIS": 0.8580243383212096, "ENBREL": 0.5699759978376014, "ESBRIET": 5.724433932889856, "HUMALOG": 2.055107300738878, "IBRANCE": 0.5865582142830306, "KEPPRA": 0.5077853689547861, "LANTUS": 1.7502741958870067, "LYRICA": 3.897744354681757, "METHOTREXATE": 1.12418115813142, "PLAVIX": 0.6050545196851727, "RITUXIMAB": 1.3885189984117272, "SIMPONI": 1.3401492028666009, "SPIKEVAX": 0.0638119682338757, "SUBOXONE": 2.53145509271739, "SUTENT": 0.3107747926286014, "TOZINAMERAN": 0.2403254108695094, "TRELEGY": 1.6692824958549792, "TRUVADA": 0.2459974043197819, "VAXZEVRIA": 0.0183447026574267, "VIAGRA": 5.270025736972341, "XELJANZ": 2.2262007125173766, "XOLAIR": 0.6451517007359293, "XTANDI": 0.8405124013104472, "ZOSTAVAX": 1.2012569645154698, "ZYPREXA": 0.4753218067925495, "null": 0.6492135141257822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12060.json
new file mode 100644
index 00000000000..effc781e06b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12060.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.118969595919109, "VAXZEVRIA": 2.259703780435612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12061.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12061.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12062.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12062.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12063.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12063.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12064.json
new file mode 100644
index 00000000000..09595e6a017
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12064.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7118929081078379, "FAMPYRA": 199.7893807329177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12065.json
new file mode 100644
index 00000000000..ba0d3567dc6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12065.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12066.json
new file mode 100644
index 00000000000..860d509de55
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12066.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 4.077639802397177, "CLOPIDOGREL": 1.7691982627771496, "COSENTYX": 0.9453084619307092, "CYMBALTA": 1.2305986435723049, "ELIQUIS": 4.850413952084125, "ENBREL": 1.407630665679375, "FIRDAPSE": 5.150840792644057, "HUMALOG": 0.8971367809236657, "IBUPROFEN": 1.6795345453515569, "LANTUS": 0.3662146147436557, "OPSUMIT": 1.2087098469217947, "PLAVIX": 231.84255012365412, "SPIKEVAX": 0.0406648955774322, "SUTENT": 0.736846349304864, "XARELTO": 3.3207938069000185, "XELJANZ": 1.2205589882152774, "null": 0.5216201810863125}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12067.json
new file mode 100644
index 00000000000..c0ffc09c123
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12067.json
@@ -0,0 +1 @@
+{"null": 2.091031042875978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12068.json
new file mode 100644
index 00000000000..db7aae691de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12068.json
@@ -0,0 +1 @@
+{"null": 1.358446126336236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12069.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12069.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1207.json
index e525c2eab07..9aa6b080760 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1207.json
@@ -1 +1 @@
-{"ARAVA": 9.212926098114693}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12070.json
new file mode 100644
index 00000000000..3e0c85d305d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12070.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.0922968743633794, "DEXAMETHASONE": 4.958684160512648, "EYLEA": 7.643247882984557, "NEPAFENAC": 642.186582802253, "NEVANAC": 439.7300494493194, "PEGASYS": 1.9113135751562025, "ROACTEMRA": 7.243480896177891, "TOBRAMYCIN": 48.27170811765266, "XELJANZ": 1.5556480801331325, "ZOSTAVAX": 2.4642837352143228, "null": 1.6301564355507163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12071.json
new file mode 100644
index 00000000000..bdc58eba500
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12071.json
@@ -0,0 +1 @@
+{"ATRIPLA": 18.301447720043832, "STRIBILD": 12.727599742554318, "TRUVADA": 9.286609988380077, "null": 0.6501642028617829}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12072.json
new file mode 100644
index 00000000000..8dad85e6f11
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12072.json
@@ -0,0 +1 @@
+{"CYMBALTA": 10.630362283209006, "MIRABEGRON": 918.679257440768, "null": 0.5949296652622242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12073.json
new file mode 100644
index 00000000000..36ecb1b4920
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12073.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.3085970266740783, "null": 0.6786973626991607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12074.json
new file mode 100644
index 00000000000..72033c03d41
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12074.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1742756324118928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12075.json
new file mode 100644
index 00000000000..dd161db73cc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12075.json
@@ -0,0 +1 @@
+{"null": 1.5608023183884372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12076.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12076.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12077.json
new file mode 100644
index 00000000000..bce24db1217
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12077.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 9.211026915418229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12078.json
new file mode 100644
index 00000000000..3754db80f1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12078.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 5.135740375057393, "null": 0.9883776974219816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12079.json
new file mode 100644
index 00000000000..10dee1e9970
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12079.json
@@ -0,0 +1 @@
+{"null": 0.9225583663233016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1208.json
index 44da735b940..900f4350194 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1208.json
@@ -1 +1 @@
-{"null": 12.348584906471904}
\ No newline at end of file
+{"ALEMTUZUMAB": 11.649696858281512, "ANIDULAFUNGIN": 27.023867156305663, "APROVEL": 4.905155051381043, "ASPARAGINASE": 8.94642099772847, "AZACITIDINE": 23.173383842655763, "AZATHIOPRINE": 2.975857183261664, "BEVACIZUMAB": 5.798327559536754, "BORTEZOMIB": 6.7030803846941245, "BUSULFAN": 25.732730182320285, "BYETTA": 1.574764113393327, "CAPECITABINE": 2.2246264500241613, "CARMUSTINE": 11.825149944179778, "CASPOFUNGIN": 9.115324444665276, "CELLCEPT": 4.6280165082204165, "CICLOSPORIN": 5.050420853308203, "CIMZIA": 0.3350419812369349, "COMIRNATY": 0.0376939689828394, "CUBICIN": 12.68108146363558, "CYTARABINE": 13.95244220028158, "DEXAMETHASONE": 3.909134349619796, "DOCETAXEL": 2.676943400840561, "DOXORUBICIN": 10.1551895804153, "ELIQUIS": 0.2749019783338864, "EVOLTRA": 66.97157870114837, "EXJADE": 3.442766723837226, "FIRDAPSE": 3.888690093487265, "FORXIGA": 1.3722678421235486, "HUMAN": 3.02087071319968, "HYDROCORTISONE": 2.658084220560053, "IBRANCE": 0.708592990441203, "INCIVO": 2.582092121152389, "IRINOTECAN": 3.017441511038173, "JAKAVI": 4.0762206434611095, "JANUMET": 0.9506271722911772, "JANUVIA": 1.4381260771873017, "JARDIANCE": 1.5300391892335838, "KEYTRUDA": 0.5670437243145565, "KYMRIAH": 4.141837613329832, "LANTUS": 0.350363280665142, "LEVETIRACETAM": 1.173405357020642, "LEVOFLOXACIN": 3.4421397428492164, "LONSURF": 3.005459280679409, "MELPHALAN": 11.243229974855714, "MEPOLIZUMAB": 1.5081199053400027, "MERCAPTOPURINE": 10.442874608071186, "METHOTREXATE": 2.802031010814693, "MYCOPHENOLATE": 10.709392825571816, "NAGLAZYME": 4.12489650054704, "NPLATE": 3.389601660596536, "OPSUMIT": 3.046115926555548, "OPTIMARK": 2.5540368463330205, "PEGASYS": 1.878375017045327, "PEGINTRON": 0.6354050586611378, "PRIVIGEN": 7.267599058867218, "RITUXIMAB": 5.973597400071235, "ROACTEMRA": 2.070514625101549, "SOLIRIS": 11.135772321064056, "SPIKEVAX": 0.0611998993758625, "SPINRAZA": 3.8972613411075407, "STELARA": 0.4531613754684163, "TIGECYCLINE": 36.34375560645968, "TRACLEER": 1.6403713601916652, "VFEND": 2.203077559365195, "VOTRIENT": 1.124422420780631, "XELJANZ": 0.7618959978532097, "YESCARTA": 8.802988200883284, "null": 0.8371558260781442}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12080.json
new file mode 100644
index 00000000000..181e54f87c6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12080.json
@@ -0,0 +1 @@
+{"EFAVIRENZ": 646.4873303681012}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12081.json
new file mode 100644
index 00000000000..176cbfa75e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12081.json
@@ -0,0 +1 @@
+{"null": 0.636331053505638}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12082.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12082.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12083.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12083.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12084.json
new file mode 100644
index 00000000000..a96a50dd56c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12084.json
@@ -0,0 +1 @@
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12085.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12085.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12086.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12086.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12087.json
new file mode 100644
index 00000000000..9df384841b9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12087.json
@@ -0,0 +1 @@
+{"COMBIVIR": 191.76965600620247, "null": 1.2374542849099122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12088.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12088.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12089.json
new file mode 100644
index 00000000000..97e02770a6f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12089.json
@@ -0,0 +1 @@
+{"null": 1.4022921896664136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1209.json
index 66b707f1459..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1209.json
@@ -1 +1 @@
-{"ENBREL": 28.954620418650947, "null": 1.3328806994464524}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12090.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12090.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12091.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12091.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12092.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12092.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12093.json
new file mode 100644
index 00000000000..5964ec2bdf4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12093.json
@@ -0,0 +1 @@
+{"EVISTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12094.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12094.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12095.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12095.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12096.json
new file mode 100644
index 00000000000..d0257630d95
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12096.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 17.97962747500936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12097.json
new file mode 100644
index 00000000000..ae8f0536c53
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12097.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 1.700627717785266, "null": 1.041492039544342}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12098.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12098.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12099.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12099.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/121.json
index 816f4ea82fd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/121.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3701493606517452}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1210.json
index b69632b29b9..6aac0677c1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1210.json
@@ -1 +1 @@
-{"ATRIPLA": 9.526918499842992}
\ No newline at end of file
+{"EYLEA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12100.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12100.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12101.json
new file mode 100644
index 00000000000..88624b43665
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12101.json
@@ -0,0 +1 @@
+{"KEPPRA": 8.880681574539636, "RECOMBINANT": 5651.195571258748, "SUBOXONE": 14.4442909842514, "null": 1.5702883309176394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12102.json
new file mode 100644
index 00000000000..7397f1511cc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12102.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 15.30048458405184, "IRON": 115.38737303967063, "null": 1.741153812063334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12103.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12103.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12104.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12104.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12105.json
new file mode 100644
index 00000000000..3bf5a5a5666
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12105.json
@@ -0,0 +1 @@
+{"APIDRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12106.json
new file mode 100644
index 00000000000..f74386f6b75
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12106.json
@@ -0,0 +1 @@
+{"null": 1.3419956826253077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12107.json
new file mode 100644
index 00000000000..6e760553ae7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12107.json
@@ -0,0 +1 @@
+{"null": 1.517046579613993}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12108.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12108.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12109.json
new file mode 100644
index 00000000000..e631993b193
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12109.json
@@ -0,0 +1 @@
+{"null": 0.8747763506310584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1211.json
index 992eaf7740f..e38769ec235 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1211.json
@@ -1 +1 @@
-{"AFINITOR": 9.948441682015956, "ALPELISIB": 144.37396459988793, "CABOMETYX": 8.067660968932168, "CAPECITABINE": 16.51210738481975, "CARMUSTINE": 62.60948007864048, "CICLOSPORIN": 1.7568503569843028, "COSENTYX": 4.529138298025233, "DENOSUMAB": 105.8441474386898, "DEXAMETHASONE": 7.5374123627980065, "DOCETAXEL": 7.0441261277357, "FASLODEX": 18.20985051590945, "FULVESTRANT": 33.43844664110897, "IBRANCE": 4.776382708544583, "JANUMET": 3.964075991786188, "KEYTRUDA": 1.23977460123982, "KYMRIAH": 14.103931280489345, "NEXAVAR": 1.987461009718897, "RIBOCICLIB": 106.27735925697556, "SUTENT": 2.530411534599225, "THALIDOMIDE": 21.1461499036955, "XTANDI": 3.5066149558470143, "ZOMETA": 103.63858104400656}
\ No newline at end of file
+{"null": 0.8156873913433854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12110.json
new file mode 100644
index 00000000000..6738f0533c2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12110.json
@@ -0,0 +1 @@
+{"BYETTA": 8.505569508829964, "JANUMET": 8.96646727959023, "JANUVIA": 6.656263467274217, "KEPPRA": 2.1114586942217763, "LONSURF": 13.986086143251596, "METHOTREXATE": 3.093133314663388, "NAGLAZYME": 23.40009916876121, "PEGASYS": 0.9824258024833544, "STELARA": 2.108777209225509, "SUTENT": 0.7545433825888744, "SYNAGIS": 8.953664599720785, "ZOSTAVAX": 4.251584238078362, "null": 2.074804602946098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12111.json
new file mode 100644
index 00000000000..df36e021113
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12111.json
@@ -0,0 +1 @@
+{"null": 0.7845551032130645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12112.json
new file mode 100644
index 00000000000..d07070390f3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12112.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.757229938531461, "ADALIMUMAB": 0.8785699825238674, "ADENURIC": 5.749656061056414, "AIMOVIG": 1.4029335910546197, "AMINOSALICYLIC": 1.295549506097866, "ANORO": 1.2761379014215797, "APIDRA": 0.5673553562357527, "ARAVA": 0.0375804862022321, "ARIPIPRAZOLE": 0.6428229825655928, "BEDAQUILINE": 10.686852435306, "BENLYSTA": 7.377874063480426, "BRAFTOVI": 7.040338454135608, "BRIDION": 7.156178516388191, "BRINTELLIX": 3.5769198695696183, "BRIVARACETAM": 5.9146100755234645, "BRIVIACT": 6.090769037701363, "BRUKINSA": 17.415428879345832, "BUPIVACAINE": 3.3745516270611597, "BUPRENORPHINE": 1.9330905460301315, "BYDUREON": 1.4825923700990915, "BYETTA": 1.1693750765132858, "CARBIDOPA": 7.567274891668005, "CELLCEPT": 0.3543185173364778, "CLOPIDOGREL": 0.7698679753903062, "COMIRNATY": 0.0277144078304117, "COSENTYX": 0.3269296762590156, "CYMBALTA": 0.2018014937442145, "DARZALEX": 1.978767099571325, "DELAMANID": 8.350310861689435, "DEXAMETHASONE": 0.2720302695094303, "ELIQUIS": 1.0084597166427065, "ENBREL": 0.4059847743446526, "ENTRESTO": 7.808026541715906, "ENZALUTAMIDE": 6.25373141845061, "EVRA": 5.971975249478788, "FAMPYRA": 27.42090909535563, "FEBUXOSTAT": 4.828899641593568, "FENTANYL": 0.3765253567306631, "FORSTEO": 0.831916226729581, "FORXIGA": 2.316455382475221, "GLUCAGON": 10.913071924340004, "HEMLIBRA": 4.63283956594904, "HUMALOG": 5.256483355881013, "INCRUSE": 9.472191046330677, "INSULIN": 0.6193424534354838, "JANUMET": 1.0889565931918377, "JANUVIA": 0.370202197059511, "KEPPRA": 1.857623728600701, "KEYTRUDA": 1.7033909668794531, "LANTUS": 1.1662883020661434, "LATUDA": 3.113041601358661, "LIXIANA": 7.08269592862228, "LYNPARZA": 1.166131100106722, "LYRICA": 2.6439670499494308, "MIMPARA": 11.165910865547437, "MULTAQ": 9.33628254728198, "NOVORAPID": 0.6861691706515198, "NUCALA": 0.5006019808260049, "OLANZAPINE": 0.3657190055813409, "ONCASPAR": 3.125211649446757, "OPSUMIT": 0.6612484394833376, "PEGASYS": 0.6543363066695838, "PEGINTRON": 1.2639426588491027, "PEMBROLIZUMAB": 1.3684591414862926, "PLAVIX": 0.5549463166203544, "PLEGRIDY": 1.750998521301519, "RANEXA": 7.858868622907402, "RELVAR": 1.6338089635723627, "ROACTEMRA": 0.4707109440424822, "ROTATEQ": 5.201048088896739, "RUBRACA": 11.124479474940012, "RUCONEST": 20.15351565744619, "SIMPONI": 12.760174510306848, "SPIKEVAX": 0.0357509310304551, "SPRYCEL": 1.1639407463142069, "STELARA": 2.1444840624497385, "SUBOXONE": 11.48629903903368, "SYCREST": 4.4439306238259295, "TOZINAMERAN": 0.0766162127552682, "TRELEGY": 3.143781399968208, "TREMFYA": 18.586390197838718, "TRULICITY": 0.99716938672231, "TWINRIX": 13.918380774975006, "VALSARTAN": 12.660336688721776, "VAXZEVRIA": 0.0193219908061847, "VIMPAT": 3.126602007759616, "VOTRIENT": 0.6188188505605691, "XARELTO": 1.4787541917151985, "XELJANZ": 0.212757008186382, "XOLAIR": 0.6000439683016294, "XTANDI": 33.0552666161666, "ZOSTAVAX": 0.2210557050818269, "null": 1.5478912335426949}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12113.json
new file mode 100644
index 00000000000..d200a60533d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12113.json
@@ -0,0 +1 @@
+{"null": 0.6604911223137445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12114.json
new file mode 100644
index 00000000000..de8fa08f917
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12114.json
@@ -0,0 +1 @@
+{"ATRIPLA": 8.116141810017218, "COMBIVIR": 15.18238783912946, "GARDASIL": 2.4842726759569738, "PEGASYS": 2.474092611415737, "TRUVADA": 1.7264158145518078, "null": 0.8192884841288586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12115.json
new file mode 100644
index 00000000000..d5133e37b2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12115.json
@@ -0,0 +1 @@
+{"ABILIFY": 52.97255007445774, "ATRIPLA": 12.338587884096142, "null": 0.9899765831711672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12116.json
new file mode 100644
index 00000000000..ba5f99a1053
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12116.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.191175327686455, "ABILIFY": 1.137665160253416, "ADALIMUMAB": 0.2085861374640787, "ADEMPAS": 7.043618286334845, "AIMOVIG": 0.7599992942142131, "ALL": 12.077456970166384, "AMBRISENTAN": 7.399869150646448, "APIDRA": 2.7754179499602847, "ARANESP": 3.04623972329616, "ARAVA": 0.7595933353829998, "ARIPIPRAZOLE": 0.5588943019586541, "ATRIPLA": 0.2291152854743927, "AUBAGIO": 9.918537017961675, "AZACITIDINE": 2.290218840538167, "AZATHIOPRINE": 1.0021449750742313, "BIKTARVY": 3.511134094175433, "BLINATUMOMAB": 8.185316307199333, "BRIVIACT": 2.3992235556479544, "BUPIVACAINE": 8.38562532101919, "BUPRENORPHINE": 1.32835766958432, "CELLCEPT": 0.5942558969645318, "CICLOSPORIN": 0.3536740438566716, "CIMZIA": 1.8784591771669312, "CINRYZE": 6.106478130705123, "CLOPIDOGREL": 0.5040209794822967, "COMIRNATY": 0.3221038727039716, "COSENTYX": 0.3122570668635639, "CYMBALTA": 1.2513563054733778, "DEXAMETHASONE": 0.3590168355250803, "ELIQUIS": 0.1901722298397666, "ENBREL": 1.122953213068648, "ENTYVIO": 0.7144846876358142, "EVENITY": 7.291176011995714, "EYLEA": 0.6308052891346083, "FENTANYL": 3.3202124851422385, "FIRDAPSE": 16.06641990265106, "HARVONI": 2.495931668685869, "HIZENTRA": 6.283238407721695, "HUMALOG": 0.5323581233524348, "HUMIRA": 3.917841974056877, "IBUPROFEN": 0.5595798170257846, "ICLUSIG": 3.4328042221818205, "INSULIN": 1.442928405832437, "JARDIANCE": 0.1934631610072988, "KALETRA": 2.5817772185126358, "KEPPRA": 3.6783938439768753, "KYPROLIS": 2.8518232924438056, "LANTUS": 5.221921925664985, "LEMTRADA": 3.508597538857829, "LEVETIRACETAM": 0.4675410910241656, "LYRICA": 1.7628961840966952, "MELATONIN": 5.3005367013444245, "MEPOLIZUMAB": 2.0721294282260456, "METHOTREXATE": 0.5831108098044469, "MICARDIS": 0.9343586060172924, "MIMPARA": 4.113144049503172, "MULTAQ": 1.661696286468244, "NEULASTA": 5.147706161421242, "NEXAVAR": 0.6124338327416312, "NPLATE": 3.153059293777298, "OFEV": 1.348167329507134, "OLANZAPINE": 0.5439337284680121, "OLYSIO": 1.8877049561451027, "OPSUMIT": 8.767605526365145, "OPTIMARK": 0.4508652785659857, "PEGASYS": 1.0549387338203535, "PEGINTERFERON": 1.1348846758881526, "PEGINTRON": 0.226288329354087, "PLAVIX": 0.9876065865201484, "PRIVIGEN": 2.043976647513423, "RANOLAZINE": 12.18475737516159, "REVLIMID": 2.469830176332058, "RIBAVIRIN": 3.18860014779985, "RINVOQ": 6.49664671793017, "RITUXIMAB": 0.7500361298270931, "RUBRACA": 1.7186387287468052, "SIMPONI": 0.2874435512620368, "SKYRIZI": 14.622455339714728, "SOLIRIS": 3.080553072674873, "SOVALDI": 2.45048167784442, "SPIKEVAX": 0.8571341861863505, "STELARA": 0.3810146402207032, "STRIBILD": 0.3377182660574592, "SUBOXONE": 3.337937939813196, "SYNAGIS": 31.67530204354482, "TAMIFLU": 0.4937522137655169, "TERIFLUNOMIDE": 7.398559640031065, "TOUJEO": 6.197248355539708, "TOVIAZ": 2.53481196005712, "TRACLEER": 2.724870025667716, "TRUVADA": 0.1553242452336149, "TUKYSA": 62.01537255047938, "VAXZEVRIA": 0.0949113491884585, "VELTASSA": 3.6204475883416447, "VENCLYXTO": 5.588489032890303, "VENETOCLAX": 7.551283964943294, "VIAGRA": 1.1246650999333987, "VIMPAT": 1.1968791977641298, "VIREAD": 1.0362490613230229, "XOLAIR": 0.3254417862483622, "XTANDI": 1.2644519409236934, "XYREM": 17.527563031262044, "ZYPREXA": 0.6084521817370261, "null": 1.332075277083292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12117.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12117.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12118.json
new file mode 100644
index 00000000000..0d898de6f15
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12118.json
@@ -0,0 +1 @@
+{"COMIRNATY": 6.250018862477208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12119.json
new file mode 100644
index 00000000000..19db7b5186c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12119.json
@@ -0,0 +1 @@
+{"ATRIPLA": 0.3706295922231705, "CHAMPIX": 1.1712294878789546, "COMIRNATY": 0.0582037022349405, "ELLAONE": 1534.5004909373415, "EVRA": 727.267258337259, "KEPPRA": 9.37786879798718, "SPIKEVAX": 0.0592727907568994, "null": 1.522936408945944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1212.json
index 23f073317a9..80e2bfab0a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1212.json
@@ -1 +1 @@
-{"ATRIPLA": 64.03061146942787, "DESCOVY": 1.688691060349759, "GENVOYA": 1.8397868735456655, "KALETRA": 8.44481672202837, "STRIBILD": 44.070120219291205, "TRUVADA": 68.51368227584163, "VIREAD": 15.37925182188718}
\ No newline at end of file
+{"BENRALIZUMAB": 1450.1922535385702, "OCEAN": 1932.5772961263, "null": 0.4712529269793651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12120.json
new file mode 100644
index 00000000000..963bb130e08
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12120.json
@@ -0,0 +1 @@
+{"NEULASTA": 2200.817635316378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12121.json
new file mode 100644
index 00000000000..ee9fd85d07a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12121.json
@@ -0,0 +1 @@
+{"null": 1.2468637412963794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12122.json
new file mode 100644
index 00000000000..b892d9872bc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12122.json
@@ -0,0 +1 @@
+{"null": 2.3420550601627514}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12123.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12123.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12124.json
new file mode 100644
index 00000000000..d676b128123
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12124.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2011924172067617, "LACOSAMIDE": 91.91817135707836, "null": 2.0189692042184784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12125.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12125.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12126.json
new file mode 100644
index 00000000000..363bcac49d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12126.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.425447133712333, "AFINITOR": 0.3358090135684892, "APIDRA": 0.6608094647548101, "APIXABAN": 0.3688824689521321, "ARIPIPRAZOLE": 1.0406962093824703, "ASPARAGINASE": 1.4217095239214488, "BENZODIAZEPINE": 4.994961236051715, "BEXSERO": 9.01527595938641, "BRIDION": 1.7362499085265926, "BUDESONIDE": 0.1940833660067535, "BUPIVACAINE": 8.087414028348016, "BUPRENORPHINE": 3.6504497657125055, "CASPOFUNGIN": 3.595607314184063, "CELECOXIB": 9.023381305198148, "CERTAGEN": 466.9102487072499, "CHAMPIX": 0.1984227012537542, "CIMZIA": 0.1226864524277826, "CLOPIDOGREL": 0.8903799166537474, "COMIRNATY": 0.1896520391938216, "CYMBALTA": 0.7586900458331524, "CYTARABINE": 0.8382348875802543, "DAPAGLIFLOZIN": 5.183436739823071, "DEXAMETHASONE": 0.9770380308498352, "DULOXETINE": 1.6829023857573104, "ELIQUIS": 0.1006479773345603, "ENOXAPARIN": 1.2316376203239776, "ENTRESTO": 0.301941804273765, "ESOMEPRAZOLE": 2.402723968397478, "EXJADE": 1.1577819005691847, "FENTANYL": 11.919354767624164, "FIRDAPSE": 1.9983796071605635, "GARDASIL": 3.267921088870078, "GLIBENCLAMIDE": 9.769237428900862, "GLUCAGON": 5.31235088320137, "HEXYON": 6.372272466333613, "HUMALOG": 0.6787261827379079, "IBRANCE": 0.1995636982060384, "IBUPROFEN": 3.490164592379625, "INFANRIX": 5.444738632450036, "INSULIN": 3.918342452178876, "INTEGRILIN": 7.232909472730528, "JANUVIA": 0.312924704125972, "JARDIANCE": 0.4007003904827886, "KEPPRA": 1.954146951178228, "KEYTRUDA": 0.3509369258794061, "LACOSAMIDE": 2.656689051524855, "LANTUS": 0.7323182708969185, "LEMTRADA": 0.8656929179763819, "LEVETIRACETAM": 2.12484495181606, "LEVOFLOXACIN": 1.2160816208059346, "LYRICA": 1.1789942120427142, "MENVEO": 3.343976929613635, "MIDAZOLAM": 9.04578037149738, "MIRCERA": 36.18778342355522, "MMRVAXPRO": 1.3288949118247195, "NAGLAZYME": 1.913548261186736, "NALOXONE": 53.95067868886571, "NIMENRIX": 2.323504947777582, "NOT": 1.9894838273566529, "OLANZAPINE": 4.83493789989098, "OPSUMIT": 0.8289588621696193, "PLAVIX": 0.679339862018913, "PREGABALIN": 4.049212449418797, "PREVENAR": 6.607538015230865, "PRIALT": 30.153420442899247, "PRIVIGEN": 1.661651387041555, "PROPRANOLOL": 6.740824789672109, "ROTARIX": 19.373948202673677, "ROTATEQ": 3.65574609356021, "SHINGRIX": 0.2373387068890434, "SOLIRIS": 0.579354167364108, "SPIKEVAX": 1.017856154179059, "SPINRAZA": 1.1261350741389102, "SUBOXONE": 4.270361095029879, "SUTENT": 0.1480896564122944, "SYNAGIS": 1.886033900895857, "TAMIFLU": 0.5136449970412471, "TOZINAMERAN": 0.5984015623854232, "TRACLEER": 1.0495809293127745, "VAXZEVRIA": 0.1908713586800363, "VELTASSA": 1.8688569534455333, "VFEND": 0.9326287214529276, "VIMPAT": 1.0996007877750715, "VORICONAZOLE": 1.381427382712608, "XOLAIR": 0.3284498861026702, "XTANDI": 0.5232458085952576, "XYREM": 1.5288208285067142, "ZOSTAVAX": 0.2115748563340815, "ZYPADHERA": 7.945294085199056, "ZYPREXA": 1.3725071263001285, "null": 2.276000268349489}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12127.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12127.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12128.json
new file mode 100644
index 00000000000..7f44089f908
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12128.json
@@ -0,0 +1 @@
+{"FENTANYL": 119.11710377306764, "MIDAZOLAM": 112.91342737985308, "null": 2.733599819475263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12129.json
new file mode 100644
index 00000000000..9fbcb14b5e4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12129.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3702118786176727, "EVRA": 1551.6748132401951, "null": 0.6982302336344438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1213.json
index f9520fdd6f2..6ee5bd3b668 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1213.json
@@ -1 +1 @@
-{"ARANESP": 5.484481087273288, "AZACITIDINE": 18.209017773186428, "BEVACIZUMAB": 25.096949235623903, "CARFILZOMIB": 30.57406977703992, "CICLOSPORIN": 1.690335878089305, "CYTARABINE": 4.96426837717329, "EXJADE": 15.083305244680997, "IBRANCE": 2.78722446056423, "JAKAVI": 4.94991667788169, "KYMRIAH": 11.097710664018605, "NEULASTA": 6.196827253205792, "NPLATE": 34.29551846940135, "OZEMPIC": 92.33942729317032, "PEGASYS": 3.567110032805449, "SOLIRIS": 3.3744199824965198, "SPRYCEL": 24.01807590942227}
\ No newline at end of file
+{"EYLEA": 485.866658994033, "MVASI": 3913.820333543581}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12130.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12130.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12131.json
new file mode 100644
index 00000000000..94b3ba48ea9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12131.json
@@ -0,0 +1 @@
+{"BRIDION": 32.19801513753912, "COMIRNATY": 0.224801903080637, "DEXMEDETOMIDINE": 240.49301258016715, "FENTANYL": 28.20440592796634, "TOZINAMERAN": 0.7252022405575261, "XOLAIR": 19.60295950321052, "null": 1.4471189905210262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12132.json
new file mode 100644
index 00000000000..d83b85e197c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12132.json
@@ -0,0 +1 @@
+{"APIXABAN": 1.77627298433731, "ARAVA": 0.0444067174399222, "BORTEZOMIB": 5.4753576457324655, "BRILIQUE": 6.990528346089608, "BUDESONIDE": 1.0477267129298895, "CAPECITABINE": 1.3691993006141248, "CELECOXIB": 2.532542003870742, "CLOPIDOGREL": 88.68802437172413, "COMIRNATY": 0.0305750440890826, "CYMBALTA": 0.2735541099206567, "CYTARABINE": 0.7719683534178367, "DEFITELIO": 16.24876588791565, "DEXAMETHASONE": 0.4511228155625916, "EBIXA": 5.840352509260915, "EFIENT": 14.17405371057757, "ELIQUIS": 7.749881910531191, "ENOXAPARIN": 33.33119908280067, "EXJADE": 0.3970974313744414, "HARVONI": 2.973907386076198, "IBUPROFEN": 4.464740182725083, "JAKAVI": 1.1766164889875128, "JANUVIA": 0.4894402583417432, "KEYTRUDA": 0.5952917429395495, "LANTUS": 0.3001020559353293, "LENVIMA": 2.073536346367236, "LEVOFLOXACIN": 0.6776240181804254, "LIXIANA": 9.885824365975452, "NEXAVAR": 2.695990227548082, "OPSUMIT": 0.8293921966434663, "PEGASYS": 0.5849434574725827, "PEGINTERFERON": 0.7415342773791198, "PLAVIX": 34.87594095462303, "PRADAXA": 9.402025287771975, "PRASUGREL": 19.259988107923004, "RIVAROXABAN": 7.84723748288804, "SOLIRIS": 0.481657573652098, "SOVALDI": 2.0939908122346926, "SPIKEVAX": 0.0366994987328927, "STIVARGA": 0.5085517500658348, "SUTENT": 0.4796688484691803, "TICAGRELOR": 123.49584936936108, "TOZINAMERAN": 0.0564808323243736, "VAXZEVRIA": 0.0118872231708743, "XARELTO": 38.23679155587341, "ZYPREXA": 0.3080063267705261, "null": 0.7544802859741732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12133.json
new file mode 100644
index 00000000000..386f9b54f5e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12133.json
@@ -0,0 +1 @@
+{"AIMOVIG": 0.7422083115357846, "ANAKINRA": 1.7457253480876915, "APIDRA": 1.4359527640515477, "ARAVA": 0.2445425211259296, "ATRIPLA": 8.624806548126564, "AUBAGIO": 0.7919498829087777, "AVANDIA": 1.435790218649063, "BENRALIZUMAB": 70.79886837946053, "CIMZIA": 1.2834217633423772, "COMIRNATY": 0.0159607707078276, "COSENTYX": 0.4440409078712438, "CYMBALTA": 0.7743660670143048, "ELIQUIS": 1.894151479613068, "ENBREL": 1.2226404746227175, "ESBRIET": 1.4198400212055675, "EVENITY": 7.887001755859747, "EVISTA": 4.951515103283462, "EXFORGE": 2.4993057898153523, "FAMPYRA": 3.5727269769949377, "FORSTEO": 8.501288982942949, "HUMALOG": 2.1465817035805768, "HUMIRA": 1.2785066492050403, "IBRANCE": 3.948078413036084, "INOVELON": 74.45402310349861, "JANUVIA": 1.2564143858244423, "JARDIANCE": 0.7737289874849188, "KALETRA": 4.229810283022959, "KEPPRA": 0.6523552702232567, "LANTUS": 3.1844174605830267, "LYRICA": 2.949667461133713, "OPSUMIT": 1.2376503974656123, "ORKAMBI": 4.906698835782488, "REVATIO": 4.382217096822105, "RITUXIMAB": 2.639992690347173, "SIMPONI": 3.051808492820276, "SOLIRIS": 0.8221567745573021, "STELARA": 0.6107494522008792, "STRIBILD": 6.600377437949353, "SUBOXONE": 4.540615718426159, "SUTENT": 0.7041841144166754, "TERIPARATIDE": 19.51463055554854, "TOZINAMERAN": 0.175254323038619, "TRELEGY": 1.6503567025648362, "TRUVADA": 7.461123161694659, "VAXZEVRIA": 0.0163711692384823, "VIAGRA": 1.3586131588445591, "VIREAD": 2.5726813399254023, "XELJANZ": 5.479339859334818, "XOLAIR": 2.070160168182349, "XTANDI": 3.156395475389211, "ZOSTAVAX": 0.6877273478082596, "ZYPREXA": 0.5955088601297811, "null": 1.013154649056807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12134.json
new file mode 100644
index 00000000000..57a24b12268
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12134.json
@@ -0,0 +1 @@
+{"null": 0.5253215492245955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12135.json
new file mode 100644
index 00000000000..4f5da7d2fdf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12135.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 202.21759055765017, "null": 0.4538027428168334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12136.json
new file mode 100644
index 00000000000..9a959c58966
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12136.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1596798712243099, "ESBRIET": 12.123322780975297, "NUCALA": 6.574447429087747, "SPIKEVAX": 0.2019008546931796, "TOZINAMERAN": 3.513778388170308, "XELJANZ": 3.791142913624001, "XOLAIR": 4.333657040116179, "null": 1.507492756491557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12137.json
new file mode 100644
index 00000000000..96d358a0865
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12137.json
@@ -0,0 +1 @@
+{"ABACAVIR": 68.09805521754512, "ABATACEPT": 1.1462416834816405, "ACLIDINIUM": 5.824487494924433, "ADALIMUMAB": 0.0932413835949358, "AFINITOR": 0.7977224467735814, "AIMOVIG": 0.7107067108393715, "AMINOSALICYLIC": 1.7528487481527688, "ANORO": 0.9324436374833572, "APIXABAN": 0.8377123871263822, "ARAVA": 0.8687366023159461, "ASPARAGINASE": 0.6518235007781776, "ATEZOLIZUMAB": 4.909671121884552, "AUBAGIO": 1.3714130931992208, "AVAMYS": 3.048495005724205, "AZATHIOPRINE": 4.365337242954816, "BENLYSTA": 2.275161673522448, "BORTEZOMIB": 1.8257046124718057, "BUDESONIDE": 1.479632522335833, "BUSULFAN": 1.8736865880965088, "BYETTA": 0.4579886832775318, "CARFILZOMIB": 2.028249328905961, "CELLCEPT": 1.5841782046001367, "CHAMPIX": 0.169480275046383, "CICLOSPORIN": 1.2473175229460007, "CIMZIA": 2.6920920034254463, "COMBIVIR": 1.2907046725223434, "COMIRNATY": 0.0823152941635899, "COSENTYX": 2.805103265915054, "CYMBALTA": 0.5499416352371934, "CYTARABINE": 2.310943791498685, "DARATUMUMAB": 5.713232229876285, "DARZALEX": 2.3404623862602683, "DESLORATADINE": 3.449905412019484, "DEXAMETHASONE": 1.780496970240698, "DOCETAXEL": 0.6103251121221198, "ELIQUIS": 0.2063525973770612, "ENBREL": 6.026749957197957, "ENTRESTO": 0.3619172050076848, "ENTYVIO": 0.988480433279317, "ESBRIET": 1.2945303123141605, "EVISTA": 1.4314925306514938, "EXJADE": 1.1672694447905194, "FASENRA": 1.4081748432857129, "FASLODEX": 0.4975892011690792, "FILGRASTIM": 1.6792109092419063, "GARDASIL": 1.321325692619287, "HIZENTRA": 8.360195266732386, "HUMALOG": 0.5537880507250488, "HUMAN": 1.0696624496683709, "HUMIRA": 1.8906869899146288, "IBRANCE": 1.151552847141625, "IBUPROFEN": 2.2768713751579965, "INCRUSE": 1.8684551187799692, "INSULIN": 5.100155942944798, "JAKAVI": 0.494676928484585, "JANUMET": 0.3366637001715764, "JANUVIA": 1.182111461768301, "JARDIANCE": 0.2177677907172524, "KEPPRA": 0.3057154612785427, "KESIMPTA": 2.434798065387689, "KEYTRUDA": 0.2690093164495013, "KYPROLIS": 2.0821663667857635, "LANTUS": 0.3374985979273695, "LEFLUNOMIDE": 6.507890063247188, "LEMTRADA": 0.9367180495291396, "LEVETIRACETAM": 0.7392597896576009, "LEVOFLOXACIN": 0.2665603661057478, "MAVENCLAD": 4.732216427040466, "MEKINIST": 0.6505482992166767, "MENVEO": 2.9832453852425265, "MEPOLIZUMAB": 5.217154405834002, "MERCAPTOPURINE": 3.036987620057717, "METHOTREXATE": 1.3167771914053503, "MMRVAXPRO": 2.375498359674113, "NAGLAZYME": 3.5069433582323035, "NINLARO": 2.1587438697775645, "NOT": 1.1442296235184986, "NPLATE": 1.3084765218286212, "NUCALA": 3.221589847963115, "OFEV": 0.6094178803383671, "OMALIZUMAB": 3.777081023991815, "OPSUMIT": 2.7250028648581077, "ORENCIA": 21.423602661702752, "ORKAMBI": 2.2518345110030458, "PEGASYS": 0.8390058206610838, "PEGINTERFERON": 0.7199258011972848, "PEGINTRON": 0.6120798851179797, "PLAVIX": 0.3063638001444641, "PREVENAR": 3.994174102787701, "PRIVIGEN": 1.711121394152513, "REVATIO": 0.7868698802425905, "REVLIMID": 1.96144364227898, "RINVOQ": 2.81947510517638, "RITUXIMAB": 1.4265151455422584, "ROACTEMRA": 3.010642611066657, "ROTATEQ": 6.1183450931921, "RUCONEST": 4.706274534941705, "SIMPONI": 1.4255212530820782, "SOLIRIS": 4.288103232440969, "SPIKEVAX": 0.0756692250634953, "SPINRAZA": 5.099917008781794, "SPRYCEL": 1.3766804997079407, "STELARA": 3.1095473195609946, "SUBOXONE": 0.4828319815862693, "SUTENT": 0.4449114389886029, "SYNAGIS": 12.008213232847556, "SYNFLORIX": 36.55224574583768, "TAMIFLU": 0.8623010396708474, "TASIGNA": 0.5381722319776202, "TOPOTECAN": 5.248301833835703, "TOZINAMERAN": 0.135570342271796, "TRACLEER": 2.6020171756417327, "TRELEGY": 1.9345249682713392, "TREMFYA": 4.529655158257165, "VAXZEVRIA": 0.038394742034628, "XELJANZ": 4.699240674108017, "XOLAIR": 3.282196683747181, "XTANDI": 0.6823255662199377, "ZOSTAVAX": 3.0645631384644383, "ZYPREXA": 0.7246127172040763, "null": 0.9001379751609597}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12138.json
new file mode 100644
index 00000000000..e43b6a45e2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12138.json
@@ -0,0 +1 @@
+{"null": 0.7301470786831146}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12139.json
new file mode 100644
index 00000000000..100f0a54d16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12139.json
@@ -0,0 +1 @@
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1214.json
index 6a8081bbe6e..ad559494f9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1214.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 3.599763130981557, "ALIMTA": 20.46912666549953, "ANAKINRA": 2.450338327596717, "ARANESP": 11.299530211324427, "ASPARAGINASE": 11.413029748863606, "AVASTIN": 1.8326967102256784, "AZACITIDINE": 12.053733958989952, "AZATHIOPRINE": 2.81029504019246, "BASILIXIMAB": 10.24004835820816, "BEVACIZUMAB": 3.153405917250005, "BLINATUMOMAB": 27.93663564208738, "BLINCYTO": 20.26168879248283, "BUPRENORPHINE": 1.3896458662519136, "BUSILVEX": 38.27667475952431, "BUSULFAN": 18.62500982922477, "CANCIDAS": 4.097566214806905, "CAPECITABINE": 1.8250856295897195, "CELLCEPT": 5.523301355179837, "CICLOSPORIN": 4.3489546215059045, "CLOFARABINE": 45.64731766443301, "COAPROVEL": 3.4775640447248573, "COMBIVIR": 3.226146820815454, "CYTARABINE": 16.592443737939597, "DASATINIB": 7.314273040132797, "DEXAMETHASONE": 2.546357660358261, "DOCETAXEL": 2.0254688072065354, "DOXORUBICIN": 5.579113675177734, "ELTROMBOPAG": 44.31260794340105, "EMEND": 8.81581645064908, "EPOETIN": 17.292079470352064, "EVOLTRA": 54.64760399084529, "EXJADE": 4.626901518625361, "FILGRASTIM": 9.8705142543334, "GANCICLOVIR": 13.67011843057223, "HYCAMTIN": 8.994056512647528, "ICLUSIG": 9.445390356738072, "INCIVO": 6.5768804494509565, "IRINOTECAN": 4.144558632726223, "JAKAVI": 3.019366158226479, "JEVTANA": 6.176863200144685, "KALETRA": 2.829445608407649, "KEPPRA": 1.6739864048757205, "KEYTRUDA": 1.0341222302042778, "KYMRIAH": 6.96689146524679, "MABCAMPATH": 29.362793696680864, "MABTHERA": 12.71043646351251, "MERCAPTOPURINE": 5.531587294169802, "METHOTREXATE": 2.9496365084246565, "NILOTINIB": 6.393172293640476, "NPLATE": 2.7653250396083124, "OZEMPIC": 23.68087113031917, "PEGASYS": 2.340701173798871, "PEGINTERFERON": 3.902716244180676, "PEMBROLIZUMAB": 1.6816380294635016, "PEMETREXED": 3.5571300506083587, "RIBAVIRIN": 2.937554684951757, "RITUXIMAB": 3.5784237601147124, "SOLIRIS": 7.500506749184425, "SPRYCEL": 4.066230714832817, "TASIGNA": 8.899644590604984, "TEMODAL": 75.61106524175345, "TEMOZOLOMIDE": 22.866841213880523, "VENETOCLAX": 5.440158670275344, "VFEND": 1.3830706292836648, "VYXEOS": 72.6453326643622, "XOFIGO": 11.195563972528, "YESCARTA": 12.491171229720694, "null": 1.0011431659256789}
\ No newline at end of file
+{"ACLIDINIUM": 4.561052833094216, "AFINITOR": 0.6604482099540748, "ALEMTUZUMAB": 2.2695764543994708, "AMIKACIN": 4.606451117559942, "APIDRA": 0.9720352147505704, "APIXABAN": 1.0613426259505978, "ARANESP": 77.48038192119076, "ARAVA": 0.145227552117023, "ASPARAGINASE": 54.875844041382486, "ATRIPLA": 0.0688643473987216, "AZATHIOPRINE": 1.3542922077320172, "BEDAQUILINE": 2.000699151960752, "BENLYSTA": 2.736413516238663, "BEVACIZUMAB": 1.052480656189781, "BUDESONIDE": 1.9044216478136684, "BUSULFAN": 5.93711609325994, "CANCIDAS": 9.865618960501134, "CARMUSTINE": 9.056731761608964, "CELLCEPT": 2.6836830207170173, "CICLOSPORIN": 6.524673376383458, "CIMZIA": 0.8251946631955248, "COMIRNATY": 0.0996546959946035, "COSENTYX": 0.8000899649941712, "CRIXIVAN": 3.544951371030247, "CUBICIN": 2.224147029965766, "CYMBALTA": 0.4484165803778249, "CYTARABINE": 11.848162457428147, "DARBEPOETIN": 53.175941204490975, "DASATINIB": 8.000523460831253, "DEXAMETHASONE": 2.778372302565254, "ELIQUIS": 0.6717090412952904, "ENBREL": 0.4833928232577776, "ENTRESTO": 0.5404522283715976, "ENTYVIO": 0.762065371152738, "EXJADE": 2.610407809077524, "FENTANYL": 0.6451825605589231, "FILGRASTIM": 5.667570815093459, "FORSTEO": 0.6668381137379839, "FORXIGA": 1.0062134944613013, "GARDASIL": 0.5243533819790738, "HIZENTRA": 3.2013226272775888, "HUMALOG": 0.913794366217444, "HUMAN": 1.7482238972673256, "HUMIRA": 1.1337954011237976, "IBRANCE": 1.5174634908242866, "INSULIN": 2.2706649557604845, "JARDIANCE": 1.09802659904503, "KALETRA": 1.006936152146657, "KEYTRUDA": 0.7959888973606382, "KYMRIAH": 1.884906598021698, "LANTUS": 0.5703882085007299, "LEVOFLOXACIN": 0.493335430540305, "MELATONIN": 5.7239721120051215, "MEPOLIZUMAB": 8.876262707418222, "METHOTREXATE": 2.365204523278816, "MYCOPHENOLATE": 4.753356925718961, "NOT": 2.682976584492553, "NUCALA": 1.1504840535287937, "OPSUMIT": 1.6286990252624782, "ORKAMBI": 4.663154745259368, "PEGASYS": 0.7268247784459037, "PEGINTRON": 1.1845052572920045, "PREGABALIN": 3.1609669384792114, "RINVOQ": 1.2087177849846442, "RITUXIMAB": 2.088178183339054, "ROACTEMRA": 1.2434564521770188, "SIMPONI": 1.8090042451602897, "SOLIRIS": 2.128518308891705, "SPIKEVAX": 0.1116302413186897, "SPRYCEL": 1.3267217281535155, "STELARA": 0.5840527015983983, "SUTENT": 1.178188765877929, "SYNAGIS": 2.467701493472656, "TACROLIMUS": 4.539085156493998, "TAMIFLU": 0.8119008828876451, "TOZINAMERAN": 0.2591843291849265, "TRELEGY": 2.51043333134109, "VAXZEVRIA": 0.1072802999441182, "VFEND": 2.1349486394030004, "VOTRIENT": 0.5815261706508512, "XELJANZ": 2.4600464873595635, "XOLAIR": 1.7290903623240683, "XTANDI": 0.6231757194021779, "ZOSTAVAX": 1.9939082233567944, "null": 0.7101764145568824}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12140.json
new file mode 100644
index 00000000000..27ca72bae66
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12140.json
@@ -0,0 +1 @@
+{"ADEMPAS": 42.805849628433954, "CELLCEPT": 9.678896194474495, "COMIRNATY": 0.2593843964633289, "ENTRESTO": 7.829788801541455, "SYNAGIS": 21.10220807567137, "null": 1.309882380751252}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12141.json
new file mode 100644
index 00000000000..4d6df6b6f7d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12141.json
@@ -0,0 +1 @@
+{"null": 2.275950152340357}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12142.json
new file mode 100644
index 00000000000..aa33d0e8a6b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12142.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 17.52272997128199, "AVAMYS": 9.218662330021168, "BUDESONIDE": 78.58362343641421, "COMIRNATY": 0.1214876966590506, "ENBREL": 1.6897246419216745, "GLYCOPYRRONIUM": 75.31106485651519, "IBRANCE": 3.0364516425144146, "MEPOLIZUMAB": 21.699239513481643, "NUCALA": 64.26177324892365, "OMALIZUMAB": 4.975529328744813, "OPSUMIT": 2.718193383967456, "PEGASYS": 0.4883304601073484, "SPIKEVAX": 0.1517422219651828, "TIVICAY": 29.04998167215432, "TOZINAMERAN": 0.6777625201828176, "TRELEGY": 3.5237051457832576, "VARENICLINE": 128.9794377523192, "VAXZEVRIA": 0.116601183856048, "XELJANZ": 1.5773576405806085, "XOLAIR": 4.361711039263777, "ZOSTAVAX": 3.9898059045978655, "null": 0.5211534834176574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12143.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12143.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12144.json
new file mode 100644
index 00000000000..ffc630a0f04
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12144.json
@@ -0,0 +1 @@
+{"AMINOSALICYLIC": 154.98763315654847, "null": 0.5916947803524273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12145.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12145.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12146.json
new file mode 100644
index 00000000000..0c76dca2448
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12146.json
@@ -0,0 +1 @@
+{"RENVELA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12147.json
new file mode 100644
index 00000000000..7cc425e585b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12147.json
@@ -0,0 +1 @@
+{"null": 0.5519605119142673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12148.json
new file mode 100644
index 00000000000..e7b14c25d22
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12148.json
@@ -0,0 +1 @@
+{"MAVENCLAD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12149.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12149.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1215.json
index e67c00fe5d9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1215.json
@@ -1 +1 @@
-{"null": 5.879276102958377}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12150.json
new file mode 100644
index 00000000000..4f7cb8d6fae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12150.json
@@ -0,0 +1 @@
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12151.json
new file mode 100644
index 00000000000..e56fdd3f680
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12151.json
@@ -0,0 +1 @@
+{"null": 0.6718273461206041}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12152.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12152.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12153.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12153.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12154.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12154.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12155.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12155.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12156.json
new file mode 100644
index 00000000000..2cf3ee1310d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12156.json
@@ -0,0 +1 @@
+{"null": 1.1180672581325903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12157.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12157.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12158.json
new file mode 100644
index 00000000000..c96e8a31e42
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12158.json
@@ -0,0 +1 @@
+{"null": 0.93936999068891}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12159.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12159.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1216.json
index aa6919be49e..3c5ba3ad88f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1216.json
@@ -1 +1 @@
-{"XOFIGO": 191.6961859485745}
\ No newline at end of file
+{"IBRANCE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12160.json
new file mode 100644
index 00000000000..7c474540fe2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12160.json
@@ -0,0 +1 @@
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12161.json
new file mode 100644
index 00000000000..1cca9fc89f5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12161.json
@@ -0,0 +1 @@
+{"FILGRASTIM": 64.22892884661363, "XTANDI": 7.205096110626176, "null": 0.7697223610419653}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12162.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12162.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12163.json
new file mode 100644
index 00000000000..34dd4d0304e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12163.json
@@ -0,0 +1 @@
+{"CELLCEPT": 21.99120672922425, "CICLOSPORIN": 14.189599884519104, "null": 0.7544423737626129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12164.json
new file mode 100644
index 00000000000..e0b7b72a73b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12164.json
@@ -0,0 +1 @@
+{"null": 0.4335501018639234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12165.json
new file mode 100644
index 00000000000..a488aaa4fe2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12165.json
@@ -0,0 +1 @@
+{"ATRIPLA": 0.963329395492794, "CRIXIVAN": 74.24484245035234, "null": 1.1688001858338957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12166.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12166.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12167.json
new file mode 100644
index 00000000000..b810b2f977d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12167.json
@@ -0,0 +1 @@
+{"CIMZIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12168.json
new file mode 100644
index 00000000000..2dfcd10865d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12168.json
@@ -0,0 +1 @@
+{"null": 0.6073702440832566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12169.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12169.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1217.json
index c609ef30056..b86aa0dff3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1217.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1217.json
@@ -1 +1 @@
-{"BUSILVEX": 2456.0126545508742}
\ No newline at end of file
+{"null": 0.7775215640317513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12170.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12170.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12171.json
new file mode 100644
index 00000000000..030666f2ec4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12171.json
@@ -0,0 +1 @@
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12172.json
new file mode 100644
index 00000000000..04352002346
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12172.json
@@ -0,0 +1 @@
+{"TIVICAY": 1037.6759625949808, "null": 0.7011289212253213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12173.json
new file mode 100644
index 00000000000..eab2f221604
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12173.json
@@ -0,0 +1 @@
+{"null": 1.599771884693706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12174.json
new file mode 100644
index 00000000000..9f5a275dc7f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12174.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 15.2108670295783, "ELIQUIS": 16.39194486927251, "LIXIANA": 43.30575831966736, "PLAVIX": 9.159013178477132, "null": 0.9704223693747916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12175.json
new file mode 100644
index 00000000000..334c4bd06a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12175.json
@@ -0,0 +1 @@
+{"null": 0.8340297510290067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12176.json
new file mode 100644
index 00000000000..687919f0f42
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12176.json
@@ -0,0 +1 @@
+{"IBUPROFEN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12177.json
new file mode 100644
index 00000000000..b30067de1a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12177.json
@@ -0,0 +1 @@
+{"null": 1.5854742411385632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12178.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12178.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12179.json
new file mode 100644
index 00000000000..ebb8ac9009d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12179.json
@@ -0,0 +1 @@
+{"SUTENT": 8.150757755093785, "null": 0.9953854686386888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1218.json
index 664b4f9f1c7..71e0a224a3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1218.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1218.json
@@ -1 +1 @@
-{"ATRIPLA": 1.9400854866871768, "COSENTYX": 13.25935635463006, "JAKAVI": 9.922623982136145, "PEGASYS": 2.9542107648907314}
\ No newline at end of file
+{"null": 0.3315020710754227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12180.json
new file mode 100644
index 00000000000..511e8b7c36f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12180.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2417459015000101, "JARDIANCE": 8.243405999302322, "null": 1.1897504718174912}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12181.json
new file mode 100644
index 00000000000..5a3c358c30c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12181.json
@@ -0,0 +1 @@
+{"null": 1.266725193580843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12182.json
new file mode 100644
index 00000000000..d35bfdc6812
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12182.json
@@ -0,0 +1 @@
+{"FILGRASTIM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12183.json
new file mode 100644
index 00000000000..b810b2f977d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12183.json
@@ -0,0 +1 @@
+{"CIMZIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12184.json
new file mode 100644
index 00000000000..e94e00ba1c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12184.json
@@ -0,0 +1 @@
+{"ARANESP": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12185.json
new file mode 100644
index 00000000000..55c409669be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12185.json
@@ -0,0 +1 @@
+{"STELARA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12186.json
new file mode 100644
index 00000000000..f2538f49959
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12186.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2650896173814547, "FORXIGA": 39.12866287542441, "JARDIANCE": 43.23239958666868, "MEPOLIZUMAB": 13.146372379895867, "TIVICAY": 120.02154130022788, "null": 0.6776605754656471}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12187.json
new file mode 100644
index 00000000000..aaaccbf1bdf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12187.json
@@ -0,0 +1 @@
+{"TRUVADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12188.json
new file mode 100644
index 00000000000..439c968904e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12188.json
@@ -0,0 +1 @@
+{"DOCETAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12189.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12189.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1219.json
index 4ba5b4683fc..0a272bf92dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1219.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1219.json
@@ -1 +1 @@
-{"CICLOSPORIN": 4.330583318151476, "EXJADE": 109.04897613639268, "ICLUSIG": 40.83326897485544, "NAGLAZYME": 51.802174574825216, "NEULASTA": 24.60955818639396, "NOXAFIL": 41.72220930244511, "SOLIRIS": 23.455756218133427, "SPRYCEL": 57.5797450471399, "VENETOCLAX": 54.07719449791175}
\ No newline at end of file
+{"ADALIMUMAB": 0.5564463513305281, "ALEMTUZUMAB": 18.33734211287426, "ASPARAGINASE": 9.318117569831845, "BORTEZOMIB": 13.62871952846341, "BUSILVEX": 83.33242876119397, "BUSULFAN": 25.104883183217183, "CELLCEPT": 6.078696249457242, "CICLOSPORIN": 6.352391381024176, "COMIRNATY": 0.0506915488551653, "CYTARABINE": 14.25766666869462, "DEXAMETHASONE": 4.262834122096557, "HUMALOG": 1.2147459196799095, "JARDIANCE": 1.5892337711065176, "MYCOPHENOLATE": 14.400579843309377, "PEGASYS": 1.088625842810568, "PEGINTRON": 2.7708975411929413, "RITUXIMAB": 5.153386683297725, "ROACTEMRA": 4.028245386811367, "SOLIRIS": 6.538036081634028, "VFEND": 3.953155004341159, "null": 1.077454525365972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12190.json
new file mode 100644
index 00000000000..a59b783102d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12190.json
@@ -0,0 +1 @@
+{"JARDIANCE": 24.27315681471841, "null": 1.0149738578763543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12191.json
new file mode 100644
index 00000000000..faa6172baa6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12191.json
@@ -0,0 +1 @@
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12192.json
new file mode 100644
index 00000000000..ef80608db89
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12192.json
@@ -0,0 +1 @@
+{"METHOTREXATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12193.json
new file mode 100644
index 00000000000..2d9735673a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12193.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2328390876315406, "TOVIAZ": 35.666869643098714, "ZOSTAVAX": 11.865976277088976, "null": 1.472184300532655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12194.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12194.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12195.json
new file mode 100644
index 00000000000..54e8a7188a8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12195.json
@@ -0,0 +1 @@
+{"ATAZANAVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12196.json
new file mode 100644
index 00000000000..f4a559082e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12196.json
@@ -0,0 +1 @@
+{"BRILIQUE": 13.21912737377838, "CLOPIDOGREL": 10.373500634344296, "COMIRNATY": 0.0831581055519798, "ELIQUIS": 33.2982801273963, "LIXIANA": 44.1060183245777, "PLAVIX": 14.490012666603349, "SUTENT": 2.4394362170736423, "VAXZEVRIA": 0.1884603962845294, "VOTRIENT": 4.879666110347417, "XTANDI": 6.414623725004774, "null": 0.7815729215373711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12197.json
new file mode 100644
index 00000000000..63a755acd72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12197.json
@@ -0,0 +1 @@
+{"RITUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12198.json
new file mode 100644
index 00000000000..6144a7c6364
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12198.json
@@ -0,0 +1 @@
+{"FORSTEO": 38.47208248559957, "null": 0.889013411256888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12199.json
new file mode 100644
index 00000000000..20d3d65689e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12199.json
@@ -0,0 +1 @@
+{"null": 1.8503316605206648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/122.json
index 33e2bba6ab3..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/122.json
@@ -1 +1 @@
-{"EXJADE": 92.08825314053009, "null": 2.660559239224512}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1220.json
index b4b1a578c67..5c41855235f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1220.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1220.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 59.13026142906176, "BUSULFAN": 39.907332911292194, "CICLOSPORIN": 32.51709629141625, "null": 1.2096867185793874}
\ No newline at end of file
+{"ALEMTUZUMAB": 93.83070218291016, "null": 0.4847839082797997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12200.json
new file mode 100644
index 00000000000..534de78847e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12200.json
@@ -0,0 +1 @@
+{"ORENCIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12201.json
new file mode 100644
index 00000000000..b96f8231714
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12201.json
@@ -0,0 +1 @@
+{"null": 2.1461455008137165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12202.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12202.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12203.json
new file mode 100644
index 00000000000..2da221f31c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12203.json
@@ -0,0 +1 @@
+{"null": 2.0689680189058968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12204.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12204.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12205.json
new file mode 100644
index 00000000000..e0e8eb634d1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12205.json
@@ -0,0 +1 @@
+{"ABILIFY": 4.542384743242111, "BETMIGA": 17.972295595713625, "COMIRNATY": 0.1124012672868769, "CYMBALTA": 5.018123817001324, "EMPAGLIFLOZIN": 21.18056836897433, "OLANZAPINE": 2.511955637737961, "SIFROL": 21.89736590855564, "SPIKEVAX": 0.2720170513653936, "TOVIAZ": 29.163745407333025, "VAXZEVRIA": 0.1880140505957716, "ZYPREXA": 10.658317809607908, "null": 2.4980283968117107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12206.json
new file mode 100644
index 00000000000..3f08e90cf5e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12206.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.2270629375916968, "ABILIFY": 1.1159080592655222, "ACTOS": 2.761196356022644, "AIMOVIG": 0.2726303832498095, "APIDRA": 0.8869113071781343, "ARIPIPRAZOLE": 2.01994326555764, "ATRIPLA": 0.1073426578855246, "AUBAGIO": 4.481490713409269, "BENLYSTA": 0.7919900598725865, "BETAFERON": 2.035830871649755, "BETMIGA": 13.598836000635425, "BIKTARVY": 1.3194355323468414, "BRINTELLIX": 1.190473594682132, "BRIVIACT": 4.584272025615266, "BUDESONIDE": 0.1903780062330518, "BUPIVACAINE": 2.994035161405056, "BUPRENORPHINE": 1.7575082997631328, "BYETTA": 0.366672282348717, "CELLCEPT": 0.4528956737404505, "CHAMPIX": 0.7511842490197232, "CICLOSPORIN": 0.2540573960160469, "CIMZIA": 0.136265190978789, "CLOPIDOGREL": 0.6237130819445631, "COMIRNATY": 0.3683641463788399, "COMTAN": 2.0885651192381705, "CYMBALTA": 0.8704410678866605, "CYTARABINE": 0.5622561008471295, "DELAMANID": 2.964045100296247, "DEXAMETHASONE": 0.5757514741318079, "DULOXETINE": 1.4505686039785566, "ELIQUIS": 0.6024334884592893, "EMPAGLIFLOZIN": 1.9494917686780309, "ENOXAPARIN": 0.9536459112770472, "ENTACAPONE": 4.874628567359238, "ENTRESTO": 0.5896792917590105, "ESMYA": 12.266455029975042, "EXELON": 7.123450693544794, "EXFORGE": 1.177308506332517, "EXJADE": 0.3572433385363488, "FAMPYRA": 4.403514928047489, "FASLODEX": 0.8980989210466156, "FENTANYL": 0.7209557570372823, "FESOTERODINE": 19.09595546932221, "FORSTEO": 5.962328050010876, "FORXIGA": 4.290453227357603, "GARDASIL": 2.2921957299204183, "HUMALOG": 0.7924273949107412, "IBRANCE": 0.6313028130402816, "IBUPROFEN": 1.1841412255334225, "INSULIN": 0.9608365417460878, "IRBESARTAN": 6.378393739002189, "JANUMET": 0.5741577318826945, "JANUVIA": 0.9189588841798302, "JARDIANCE": 3.712517579071693, "KALETRA": 0.6248706822091025, "KEPPRA": 2.041016616701092, "KETOCONAZOLE": 9.487403754425392, "KEYTRUDA": 0.3805327734187343, "LANTUS": 0.3878951687536354, "LATUDA": 2.102421555931233, "LEMTRADA": 1.3670486274103628, "LEVETIRACETAM": 0.3765953397345739, "LEVOFLOXACIN": 0.4352294137692502, "LYRICA": 2.424918931393877, "MEMANTINE": 8.13235659100843, "MENVEO": 1.7993120510409195, "METHOTREXATE": 0.5639270287297143, "MMRVAXPRO": 0.3899387547539931, "MOVYMIA": 9.093557188303851, "NEXAVAR": 0.299113022352605, "NOT": 2.281109379589915, "OLANZAPINE": 2.250519046087195, "OXYBUTYNIN": 7.888278650636662, "PANTOPRAZOLE": 3.346636685219095, "PEGASYS": 0.4241841767391099, "PEGINTRON": 0.5934768741060634, "PLAVIX": 0.6175151035278356, "PLEGRIDY": 1.2384541850900097, "PREGABALIN": 1.1518003230189056, "RIBAVIRIN": 0.6573419181144333, "RISPERIDONE": 4.349393433948786, "SAXENDA": 1.0299860914692027, "SHINGRIX": 0.4910738945157267, "SIMPONI": 0.372726187442793, "SPIKEVAX": 0.4779644480285532, "STELARA": 0.1843057058015994, "SUBOXONE": 0.4141620720057336, "SUFENTANIL": 2.5027041985782965, "SUTENT": 0.4276840083342456, "SYCREST": 9.408509834622276, "TAMIFLU": 0.8111051042785011, "TOVIAZ": 12.796172326019976, "TOZINAMERAN": 0.6524260423303879, "TRELEGY": 0.8125674708090577, "TRUVADA": 0.1197443971457712, "VAXZEVRIA": 0.3228743100553787, "VFEND": 0.8524084715655922, "VIAGRA": 0.8391419546095505, "VIMPAT": 1.194835094226577, "XELJANZ": 0.5260587642372673, "XTANDI": 2.1573132057832267, "ZOSTAVAX": 1.8979107688458765, "ZYPADHERA": 2.6666043959039936, "ZYPREXA": 3.379143310864157, "null": 1.9621455745855387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12207.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12207.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12208.json
new file mode 100644
index 00000000000..16801f05ee8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12208.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.589279542398873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12209.json
new file mode 100644
index 00000000000..bd006971aa2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12209.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 6.685174420729597, "CLOPIDOGREL": 9.722797886507577, "COMIRNATY": 0.2608369246014607, "null": 1.3822654475560263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1221.json
index 7ac548e66fb..77affe422ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1221.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1221.json
@@ -1 +1 @@
-{"ATRIPLA": 6.875897753192371, "HEPSERA": 190.04427165810185, "KALETRA": 92.4327376636144}
\ No newline at end of file
+{"ALEMTUZUMAB": 34.73286703398469, "COMIRNATY": 0.0879150960136999, "JARDIANCE": 3.352886956335501, "null": 0.9697620368498858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12210.json
new file mode 100644
index 00000000000..cfd31419908
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12210.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.8220787893828372, "AERIUS": 1.3226560687179931, "AFINITOR": 0.2186481880697091, "AIMOVIG": 0.1726944897803993, "ALIMTA": 0.3035113038051373, "ANORO": 6.200385379785451, "APIXABAN": 0.2401827507504671, "APROVEL": 1.498649515804029, "ARAVA": 0.0204201263603948, "ARIPIPRAZOLE": 1.0019951141984758, "ATRIPLA": 0.0664464034199045, "AUBAGIO": 0.6643118783358237, "BEDAQUILINE": 0.4949658101538652, "BENLYSTA": 0.2220934151366406, "BETMIGA": 43.47283709846098, "BRINTELLIX": 2.126641550868607, "BUPIVACAINE": 6.602756607819134, "BUPRENORPHINE": 1.191180118535268, "BUVIDAL": 6.081981140639653, "BYETTA": 0.2629930827623721, "CABAZITAXEL": 3.2454920203020583, "CELECOXIB": 3.729241956348934, "CELLCEPT": 0.3166498496350083, "CHAMPIX": 0.6342873398258816, "CICLOSPORIN": 0.1298364519341615, "CLOPIDOGREL": 0.3944550778754397, "COAPROVEL": 1.1244711513523848, "COMIRNATY": 0.0909614487599746, "COMTAN": 1.0675593233854557, "CYMBALTA": 2.358024258672537, "CYTARABINE": 0.2110877109742127, "DEXAMETHASONE": 0.8166842330556985, "DOCETAXEL": 0.2497738146068902, "DULOXETINE": 2.0871516776420598, "EBIXA": 3.4123145560250343, "ELIQUIS": 0.5416281829374813, "EMEND": 1.2860422667760738, "EMPAGLIFLOZIN": 0.8800712223161292, "ENTACAPONE": 3.306935925816632, "ENTRESTO": 0.8364411859086279, "ERLEADA": 1.5248784850144108, "EXFORGE": 0.5628841711368016, "EXJADE": 0.2938953443493675, "FAMPYRA": 1.2930400505387147, "FENTANYL": 2.339312690317745, "FIRDAPSE": 0.7139909446147078, "FORSTEO": 0.3989046907630479, "FORXIGA": 2.004273730320844, "FYCOMPA": 2.9912568767672965, "GARDASIL": 0.2242759932920373, "HIZENTRA": 0.4210674941756497, "HUMALOG": 0.1734452234710867, "IBRANCE": 0.1710791197391501, "IBUPROFEN": 0.2079757039463347, "ICLUSIG": 0.7750444873694364, "INCRUSE": 8.69593521411426, "INLYTA": 0.4776177476951153, "INVEGA": 2.343642392080649, "IPILIMUMAB": 0.4034294721363159, "IRBESARTAN": 0.7135474665356754, "JANUMET": 0.7079898901069763, "JANUVIA": 0.4694372485214321, "JARDIANCE": 1.3830563649982477, "JEVTANA": 0.7618956559755582, "KEPPRA": 0.6277395723459719, "KETOCONAZOLE": 4.849656710869163, "KEYTRUDA": 0.3378781959355197, "LANTUS": 0.1367499363708899, "LATUDA": 3.586005534046205, "LEMTRADA": 1.262369899528219, "LEVEMIR": 0.8509139078921658, "LEVETIRACETAM": 0.2858076768668492, "LEVOFLOXACIN": 0.2051792130984894, "LONSURF": 0.551823488989124, "LYRICA": 3.2422165366087485, "MEKINIST": 0.4040365664290951, "MELATONIN": 1.8375544681089369, "MEPOLIZUMAB": 0.4158572045248231, "MICARDIS": 0.3846903533868477, "MIRABEGRON": 24.650958829031502, "NOT": 0.6716785206432145, "NUCALA": 0.1617643024099559, "OLANZAPINE": 2.806900265147735, "OPDIVO": 0.2378288714822971, "OPSUMIT": 0.1674490508097924, "ORENCIA": 2.2216236193284256, "OXYBUTYNIN": 22.1011199461109, "PANTOPRAZOLE": 0.413663719231579, "PEGASYS": 0.2993392193287432, "PEGINTRON": 0.3310895330611294, "PEMBROLIZUMAB": 0.6564936598855691, "PLAVIX": 0.4797817019192112, "PREGABALIN": 1.4451285953354918, "PRITOR": 8.228538927804658, "QARZIBA": 7.054956469212461, "RANOLAZINE": 4.446116108841981, "RELVAR": 2.5965041655489483, "RINVOQ": 0.3026022540163254, "RISPERIDONE": 1.3836679275413255, "SAXENDA": 0.4855626785969393, "SHINGRIX": 0.2000574521692364, "SILODOSIN": 10.201231061991292, "SIMPONI": 0.4239644797403167, "SPIKEVAX": 0.0865383587074283, "SPINRAZA": 1.8595017734224064, "SPIRONOLACTONE": 1.0335497142024934, "SPRYCEL": 0.335418346645625, "STALEVO": 1.2859950257181088, "STELARA": 0.4151216321481988, "STIVARGA": 0.6801110628348599, "SUBOXONE": 0.8371918569820538, "SUFENTANIL": 1.0098138643878154, "SUTENT": 0.7409558067040604, "SYCREST": 5.11871772005341, "TAMIFLU": 1.0282874808210023, "TOVIAZ": 300.15280838641866, "TOZINAMERAN": 0.1794631348499908, "TRELEGY": 13.435829370242526, "VAXZEVRIA": 0.0882980055230343, "VELTASSA": 0.7396723384633024, "VFEND": 0.4674501010935852, "VIAGRA": 2.471502722925835, "VICTOZA": 0.3474136273153828, "VIMPAT": 0.6708249712070938, "XALKORI": 0.6043182344757481, "XELJANZ": 0.1492446206727603, "XOFIGO": 1.5301661478522013, "XOLAIR": 0.1209553622653373, "XTANDI": 1.2841957656108585, "ZOSTAVAX": 0.5116886351790152, "ZYPADHERA": 1.27492654398601, "ZYPREXA": 2.6311103210662243, "null": 2.3079155721263973}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12211.json
new file mode 100644
index 00000000000..1b8fa553ff2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12211.json
@@ -0,0 +1 @@
+{"null": 0.6354253074591604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12212.json
new file mode 100644
index 00000000000..9c21761c4fe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12212.json
@@ -0,0 +1 @@
+{"null": 0.5610331033905649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12213.json
new file mode 100644
index 00000000000..99102c40b76
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12213.json
@@ -0,0 +1 @@
+{"ADENURIC": 206.8367007482617, "ALEMTUZUMAB": 185.234680641476, "LEMTRADA": 56.49172142686853, "null": 0.4102570520557005}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12214.json
new file mode 100644
index 00000000000..60b47f4947d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12214.json
@@ -0,0 +1 @@
+{"null": 1.80659874257022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12215.json
new file mode 100644
index 00000000000..fbfc01efcec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12215.json
@@ -0,0 +1 @@
+{"BINIMETINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12216.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12216.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12217.json
new file mode 100644
index 00000000000..c1bbb4b698c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12217.json
@@ -0,0 +1 @@
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12218.json
new file mode 100644
index 00000000000..d9d7fb53c5e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12218.json
@@ -0,0 +1 @@
+{"MEPOLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12219.json
new file mode 100644
index 00000000000..ca3e00d2dad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12219.json
@@ -0,0 +1 @@
+{"JARDIANCE": 53.39076118069734, "MIDAZOLAM": 108.9581473077792, "null": 0.3760337209184556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1222.json
index 310a872b469..8d7a72ef05e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1222.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1222.json
@@ -1 +1 @@
-{"VOTRIENT": 12.676781439013318}
\ No newline at end of file
+{"null": 1.6713781382888988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12220.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12220.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12221.json
new file mode 100644
index 00000000000..27f63782965
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12221.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.555178453329811, "JARDIANCE": 16.73193431627262, "null": 0.5576729931074925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12222.json
new file mode 100644
index 00000000000..4212bbcf579
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12222.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 3.202506374159399, "ARAVA": 0.2884271909003781, "ATRIPLA": 0.6543184032195689, "BUDESONIDE": 1.7633710431037612, "BYETTA": 4.214876729977447, "COMIRNATY": 0.1353074514116893, "CYMBALTA": 0.7879816218081219, "ELIQUIS": 1.5116206510909007, "FAMPYRA": 6.581052674154903, "FORXIGA": 4.031442303062748, "GARDASIL": 1.3209831646442924, "HYDROCORTISONE": 18.617661348648635, "JARDIANCE": 1.807962639750756, "NUCALA": 4.845669594143235, "SUTENT": 2.0129103327392257, "TECFIDERA": 83.19803877622537, "TOVIAZ": 13.922313747760397, "TOZINAMERAN": 0.2471683374991091, "TRELEGY": 5.0111191528680274, "VAXZEVRIA": 0.1006847675403645, "XELJANZ": 1.343582147603338, "XTANDI": 2.7969391403258377, "ZOSTAVAX": 2.7422110478816446, "null": 1.1057327829867272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12223.json
new file mode 100644
index 00000000000..85b6433418f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12223.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12224.json
new file mode 100644
index 00000000000..00e8dd70a50
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12224.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 15.61293214656312, "CELLCEPT": 6.202962028833478, "CICLOSPORIN": 4.386177833131599, "COMIRNATY": 0.1340729287089697, "CYMBALTA": 5.474634931287365, "FORXIGA": 12.635329997490274, "JARDIANCE": 7.237083647321228, "METHOTREXATE": 5.64478618414307, "MIRABEGRON": 113.56636034178511, "NOT": 22.279676895935197, "OCEAN": 694.9936888732852, "SIMPONI": 3.539460010100079, "TOZINAMERAN": 0.5122818737262699, "XELJANZ": 5.655407945222626, "null": 0.6401880534266411}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12225.json
new file mode 100644
index 00000000000..12711e09647
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12225.json
@@ -0,0 +1 @@
+{"null": 0.8840673756965324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12226.json
new file mode 100644
index 00000000000..0194ed96b47
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12226.json
@@ -0,0 +1 @@
+{"FORXIGA": 79.28837300154973, "JARDIANCE": 48.16963701929176, "null": 0.5674065237541014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12227.json
new file mode 100644
index 00000000000..900a94c288e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12227.json
@@ -0,0 +1 @@
+{"METHOTREXATE": 33.66511738669085, "null": 0.4627638120945879}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12228.json
new file mode 100644
index 00000000000..85282cbf8c4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12228.json
@@ -0,0 +1 @@
+{"null": 0.9170964863656456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12229.json
new file mode 100644
index 00000000000..be35e5620a4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12229.json
@@ -0,0 +1 @@
+{"CELLCEPT": 75.60446572818122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1223.json
index a9e76d2e155..5c1e2464c9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1223.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1223.json
@@ -1 +1 @@
-{"null": 1.261936356305691}
\ No newline at end of file
+{"ASPARAGINASE": 94.27717341224188, "null": 0.674629443491877}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12230.json
new file mode 100644
index 00000000000..7e96ae85221
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12230.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1322667430928872, "EFAVIRENZ": 86.96421101221651, "JARDIANCE": 12.087891655402556, "SPIKEVAX": 0.5276315641059448, "null": 0.421910029494292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12231.json
new file mode 100644
index 00000000000..01ff81e6902
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12231.json
@@ -0,0 +1 @@
+{"null": 2.8296882371942016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12232.json
new file mode 100644
index 00000000000..3231f10b7a5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12232.json
@@ -0,0 +1 @@
+{"ATRIPLA": 0.8805684949343726, "BUSULFAN": 15.605580871404497, "CICLOSPORIN": 2.704948582400178, "COMIRNATY": 0.0580613228209429, "FAMPYRA": 31.134075646569173, "JARDIANCE": 4.06784229522905, "KALETRA": 8.909060317757262, "KEYTRUDA": 1.539000261942273, "SUTENT": 1.4551039629225988, "TOVIAZ": 24.78550128291997, "XTANDI": 5.677076881147115, "null": 1.1779434139240403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12233.json
new file mode 100644
index 00000000000..6dbf6116000
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12233.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.584813214332773, "VAXZEVRIA": 0.6563987999430487, "null": 1.1445181331829632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12234.json
new file mode 100644
index 00000000000..2980f99df95
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12234.json
@@ -0,0 +1 @@
+{"ABACAVIR": 2.0456032338440244, "ALEMTUZUMAB": 25.36874430316404, "BELIMUMAB": 185.6437364662365, "BENLYSTA": 7.167127960484031, "BRILIQUE": 7.0193877182608775, "CIMZIA": 1.0841771720617686, "COMIRNATY": 0.2993494712890541, "ELIQUIS": 0.8900753877076891, "FORSTEO": 4.530873981586754, "FORXIGA": 6.617965353631789, "IRBESARTAN": 47.405342593667335, "JARDIANCE": 4.752973769098555, "LYRICA": 3.161600858311834, "MEPOLIZUMAB": 3.9385853125583945, "SPIKEVAX": 0.4475525482042243, "TOVIAZ": 7.234271439301564, "TOZINAMERAN": 0.8395688448982292, "VAXZEVRIA": 0.2599384993011614, "null": 1.1417555501420604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12235.json
new file mode 100644
index 00000000000..3cac1637738
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12235.json
@@ -0,0 +1 @@
+{"null": 0.5365168473202504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12236.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12236.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12237.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12237.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12238.json
new file mode 100644
index 00000000000..e28923d0706
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12238.json
@@ -0,0 +1 @@
+{"null": 2.6942395959759136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12239.json
new file mode 100644
index 00000000000..476bb87ccad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12239.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 21.26085129117077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1224.json
index 534d32022a9..093330a9d60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1224.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1224.json
@@ -1 +1 @@
-{"ABRAXANE": 1.2198347457820218, "ACCOFIL": 22.1530615163487, "ACLASTA": 5.057622175263924, "ADEFOVIR": 6.414905892664548, "AFINITOR": 1.3446831855226236, "APROVEL": 1.018239864044513, "ATRIPLA": 1.692594984026222, "AXITINIB": 1.1436174574112272, "BIKTARVY": 1.2788459658810236, "BONVIVA": 18.81208898325868, "BORTEZOMIB": 1.6338228529588268, "BOSULIF": 3.1607142444926475, "CABAZITAXEL": 2.7723359135096217, "CAELYX": 1.0305341292125672, "CARFILZOMIB": 1.633537259867167, "COMIRNATY": 1.2322865750548326, "CONTRAST": 2.739135943318313, "COVID19": 1.946487736317412, "DARATUMUMAB": 3.891300656337952, "DARZALEX": 1.9138186338750889, "DASATINIB": 3.153923791661148, "DENOSUMAB": 3.847668578436301, "DEXAMETHASONE": 1.1866905730008912, "DOCETAXEL": 2.480038351855703, "DOXORUBICIN": 1.5231205063030984, "ENTECAVIR": 5.983482777487846, "ENZALUTAMIDE": 2.212184549356868, "EPOETIN": 2.433837319595624, "EVENITY": 3.3556331403174613, "EVEROLIMUS": 4.131972932645251, "EVISTA": 2.965721220010123, "FASENRA": 1.3355897754404296, "FASLODEX": 5.574556169677578, "FILGRASTIM": 13.280394044322543, "FORSTEO": 9.08629431651199, "FULVESTRANT": 3.261699810429383, "GENVOYA": 1.9348535301403968, "GLIVEC": 1.029033142432015, "HEPSERA": 13.581229409506877, "HERCEPTIN": 1.461016225711255, "HYDROXYCARBAMIDE": 8.953866926559531, "IBRANCE": 3.3183384413566097, "ICLUSIG": 2.137808468907818, "ILARIS": 5.148619987595221, "IMBRUVICA": 2.08765931535678, "INLYTA": 1.254942001741729, "JAKAVI": 2.4742777383158425, "JEVTANA": 2.434318070513375, "KESIMPTA": 1.2886406826098409, "KISQALI": 2.0384641392787737, "LYNPARZA": 1.7612798784110768, "MIMPARA": 3.456732685835604, "MOVYMIA": 4.431744975003668, "NEULASTA": 33.27338902052712, "NIVESTIM": 40.68673118342683, "NPLATE": 1.7691202200315312, "OCTREOTIDE": 4.514649864366543, "OPTIMARK": 2.506116327897064, "PEGASYS": 1.4361176497408157, "PEGFILGRASTIM": 26.96172059293343, "PEGINTRON": 1.1371660247052011, "PERJETA": 2.049112437286263, "PLEGRIDY": 1.468465797912362, "PROLIA": 2.833537344080409, "PROTELOS": 2.520865924539914, "REBLOZYL": 23.16044402044602, "RIBOCICLIB": 2.2162236238182427, "RUXOLITINIB": 1.977110850932401, "SPRYCEL": 2.4044314156253144, "STRIBILD": 1.0455071405969187, "SUTENT": 1.141653363002835, "TASIGNA": 2.1865317160232878, "TAXOTERE": 1.6599577639022287, "TENOFOVIR": 4.274348497211423, "TERIPARATIDE": 4.1287137660365465, "TERROSA": 6.888177846802693, "TEVAGRASTIM": 27.846789229238368, "TOZINAMERAN": 1.1077598336897905, "TRUVADA": 1.0835564831225335, "VAXZEVRIA": 2.4235343511251, "VIREAD": 2.7399374512305257, "VORICONAZOLE": 1.8899045414892464, "XELJANZ": 1.0385417625411502, "XOFIGO": 11.592977078852812, "XTANDI": 3.758905539395671, "ZARZIO": 32.51999598045862, "ZOMETA": 3.57574804264202}
\ No newline at end of file
+{"COMIRNATY": 1.4316919049625605, "COSENTYX": 14.327199733125411, "GARDASIL": 5.636362887135623, "null": 0.7335229403895795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12240.json
new file mode 100644
index 00000000000..2e447a79f9c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12240.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 10.103762871270929, "ATRIPLA": 0.5156995337324634, "CHAMPIX": 1.8507113551139005, "COMIRNATY": 0.1479306484531956, "EXJADE": 3.849751641714897, "FENTANYL": 4.883546652936865, "FORXIGA": 12.060240800981637, "JARDIANCE": 1.8771474889030328, "SPIKEVAX": 0.1621921695248616, "SUTENT": 1.0098593710989043, "TOZINAMERAN": 0.4445210986169274, "VAXZEVRIA": 0.2310318369520951, "null": 1.6249922619642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12241.json
new file mode 100644
index 00000000000..e011d870350
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12241.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 9.932330184936642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12242.json
new file mode 100644
index 00000000000..e8bec2b5dfb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12242.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12243.json
new file mode 100644
index 00000000000..92f86feeed4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12243.json
@@ -0,0 +1 @@
+{"null": 2.143246175282272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12244.json
new file mode 100644
index 00000000000..87e990df424
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12244.json
@@ -0,0 +1 @@
+{"null": 3.59908058992106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12245.json
new file mode 100644
index 00000000000..90fb8e8bcef
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12245.json
@@ -0,0 +1 @@
+{"FORSTEO": 157.2870200041915, "HEPSERA": 170.04222116763145, "null": 0.951520725305524}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12246.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12246.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12247.json
new file mode 100644
index 00000000000..2c261eeb256
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12247.json
@@ -0,0 +1 @@
+{"null": 1.9007439671806237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12248.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12248.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12249.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12249.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1225.json
index 361f5c23dcb..a424c2608b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1225.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1225.json
@@ -1 +1 @@
-{"ZOMETA": 1451.4647828344212}
\ No newline at end of file
+{"ENTYVIO": 220.60821015736235, "GARDASIL": 18.941074702803203, "null": 0.6594217418587257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12250.json
new file mode 100644
index 00000000000..536d51d6a63
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12250.json
@@ -0,0 +1 @@
+{"null": 3.484806290653003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12251.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12251.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12252.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12252.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12253.json
new file mode 100644
index 00000000000..e7970a798dd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12253.json
@@ -0,0 +1 @@
+{"BETMIGA": 24.517146887549977, "TOVIAZ": 61.63556198322418, "TOZINAMERAN": 0.4479892235134756, "TRELEGY": 12.110124726686555, "VAXZEVRIA": 0.2728799959429789, "null": 2.854728679131053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12254.json
new file mode 100644
index 00000000000..4bc7996fc89
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12254.json
@@ -0,0 +1 @@
+{"CELECOXIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12255.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12255.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12256.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12256.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12257.json
new file mode 100644
index 00000000000..d6d29b4c49f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12257.json
@@ -0,0 +1 @@
+{"JARDIANCE": 132.51972959503632, "null": 0.1905686738196838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12258.json
new file mode 100644
index 00000000000..d80b295b84e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12258.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 19.361307958764133, "APIDRA": 14.100172757264286, "COMIRNATY": 0.0855946322615936, "FORXIGA": 55.4267246337684, "HUMALOG": 10.57261347799306, "INSULIN": 8.97634961452124, "JARDIANCE": 48.29836515409082, "LANTUS": 7.595116202992573, "NOVORAPID": 32.51346036899803, "null": 0.4599849651734293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12259.json
new file mode 100644
index 00000000000..0d49d3f7af6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12259.json
@@ -0,0 +1 @@
+{"EXJADE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1226.json
index db1181b9fe5..2668a7f8d54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1226.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1226.json
@@ -1 +1 @@
-{"ARAVA": 11.271256090841714, "TOZINAMERAN": 3.4615000751320717}
\ No newline at end of file
+{"JARDIANCE": 20.05033774379761, "null": 0.8154117604011806}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12260.json
new file mode 100644
index 00000000000..687919f0f42
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12260.json
@@ -0,0 +1 @@
+{"IBUPROFEN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12261.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12261.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12262.json
new file mode 100644
index 00000000000..0fefb6dedf9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12262.json
@@ -0,0 +1 @@
+{"PREVENAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12263.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12263.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12264.json
new file mode 100644
index 00000000000..005f9038f86
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12264.json
@@ -0,0 +1 @@
+{"ARANESP": 3.186631973432911, "AUBAGIO": 1.8807480898727829, "BETMIGA": 12.27151118323859, "CHAMPIX": 1.1245804838333897, "COMIRNATY": 0.3246412323976667, "CYMBALTA": 1.0631063594717167, "DULOXETINE": 14.258842457291031, "ELIQUIS": 0.8017333148082211, "FASLODEX": 9.471749725649746, "FORSTEO": 2.8350637743882787, "FORXIGA": 9.904724585235602, "IBRANCE": 1.8002107698396697, "JARDIANCE": 10.204814145278556, "LANTUS": 1.2816220336443207, "PEGASYS": 1.1766827035077256, "SIMPONI": 1.696441283968661, "SPIKEVAX": 0.2116889599716761, "SUTENT": 1.0241649022261698, "TAMIFLU": 25.035341587166027, "TOZINAMERAN": 0.4999484534596065, "VAXZEVRIA": 0.318230245166879, "XELJANZ": 1.7954804480348203, "null": 1.3782605602370042}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12265.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12265.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12266.json
new file mode 100644
index 00000000000..b9f764e7856
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12266.json
@@ -0,0 +1 @@
+{"null": 6.356412305631743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12267.json
new file mode 100644
index 00000000000..27eaa4bcaa2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12267.json
@@ -0,0 +1 @@
+{"null": 3.0548440407645794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12268.json
new file mode 100644
index 00000000000..d59d0d12740
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12268.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 7.722021692636103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12269.json
new file mode 100644
index 00000000000..a1524251737
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12269.json
@@ -0,0 +1 @@
+{"ACTOS": 9.784746227075605, "AFINITOR": 3.64710298360381, "ATRIPLA": 0.2003986416892805, "BASILIXIMAB": 11.94043871972373, "BEDAQUILINE": 6.362609138555015, "BUMETANIDE": 7.375202630350306, "CELLCEPT": 2.955895877724041, "CHAMPIX": 0.6338688999056465, "CICLOSPORIN": 3.277084637028369, "CLOPIDOGREL": 0.5262124987060496, "COMIRNATY": 0.0936834300776806, "COSENTYX": 0.6731045419345895, "CYMBALTA": 0.3938173515692386, "DEXAMETHASONE": 0.9417834324492808, "ELIQUIS": 0.3562319324198078, "ENTRESTO": 4.677211542612704, "EVISTA": 3.0104564407669736, "EXJADE": 8.527765378255916, "FENTANYL": 0.8455581372182541, "FORSTEO": 0.8739391716630474, "FORXIGA": 2.492415323430719, "HIZENTRA": 6.543257373458443, "IBUPROFEN": 1.75978956521612, "IRBESARTAN": 6.310746909011693, "JANUMET": 0.9935920561653622, "JARDIANCE": 0.5073301850773397, "KEPPRA": 0.5420694152271307, "KEYTRUDA": 0.5433043539036087, "LEVETIRACETAM": 0.967801211204303, "LEVOFLOXACIN": 1.5688229244720886, "MICARDIS": 1.934091596471536, "NEXAVAR": 0.8709931844702676, "NOT": 3.824418318454219, "OLANZAPINE": 0.6728882182953235, "OPSUMIT": 2.601989582441215, "PEGASYS": 0.2470847308427085, "PLAVIX": 0.9053076513654822, "RASILEZ": 5.28406996843585, "ROTATEQ": 9.802830415513, "SOLIRIS": 2.3649344848141136, "SPIKEVAX": 0.0639727285128875, "SPIRONOLACTONE": 5.1962731173255845, "STIVARGA": 1.4899921283131483, "SUTENT": 0.7107266580344559, "TOVIAZ": 2.961186779368628, "TOZINAMERAN": 0.1416903376584211, "TRACLEER": 2.5096190737698203, "VALSARTAN": 8.510387614986618, "VAXZEVRIA": 0.0528964555194474, "XELJANZ": 0.6345153604792869, "XTANDI": 1.0922731698321002, "null": 2.1186093778646318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1227.json
index 54e884746f3..6f239bd5424 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1227.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1227.json
@@ -1 +1 @@
-{"DELAMANID": 211.4616179789929, "GARDASIL": 10.29040971684035}
\ No newline at end of file
+{"ARANESP": 2322.6947118828784, "null": 0.0570647666968173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12270.json
new file mode 100644
index 00000000000..10e3910c501
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12270.json
@@ -0,0 +1 @@
+{"CHAMPIX": 2.427848163239457, "COMIRNATY": 0.0619338862055984, "ENTRESTO": 4.504381016562586, "FORSTEO": 4.081167707268572, "FORXIGA": 12.470323322151131, "JARDIANCE": 25.11767214787369, "KEPPRA": 2.76370825029842, "VAXZEVRIA": 0.2272684505881455, "null": 1.7661296781335118}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12271.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12271.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12272.json
new file mode 100644
index 00000000000..0b20701da20
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12272.json
@@ -0,0 +1 @@
+{"HEPSERA": 1118.0887978753017, "null": 0.2484307313890143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12273.json
new file mode 100644
index 00000000000..b42d74b93e7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12273.json
@@ -0,0 +1 @@
+{"ZEJULA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12274.json
new file mode 100644
index 00000000000..db7aae691de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12274.json
@@ -0,0 +1 @@
+{"null": 1.358446126336236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12275.json
new file mode 100644
index 00000000000..b758c8aa2b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12275.json
@@ -0,0 +1 @@
+{"null": 2.222531818087429}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12276.json
new file mode 100644
index 00000000000..748a001f23a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12276.json
@@ -0,0 +1 @@
+{"EXJADE": 17.29961655292397, "LUPKYNIS": 2514.128171906478, "null": 0.2579073346424794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12277.json
new file mode 100644
index 00000000000..432b8caddaf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12277.json
@@ -0,0 +1 @@
+{"null": 1.9017580592704937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12278.json
new file mode 100644
index 00000000000..df802cbb3ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12278.json
@@ -0,0 +1 @@
+{"null": 2.739513379418182}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12279.json
new file mode 100644
index 00000000000..b7dd848023e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12279.json
@@ -0,0 +1 @@
+{"null": 2.7720703895068923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1228.json
index 593e27d1e26..5478f9a3de4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1228.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1228.json
@@ -1 +1 @@
-{"ZOSTAVAX": 34.32192604934259, "null": 1.1610991056642364}
\ No newline at end of file
+{"UPADACITINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12280.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12280.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12281.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12281.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12282.json
new file mode 100644
index 00000000000..90e9774156b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12282.json
@@ -0,0 +1 @@
+{"null": 1.676957700722595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12283.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12283.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12284.json
new file mode 100644
index 00000000000..f9b6dd4558e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12284.json
@@ -0,0 +1 @@
+{"TRIENTINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12285.json
new file mode 100644
index 00000000000..3982c4303f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12285.json
@@ -0,0 +1 @@
+{"null": 0.6842411932383017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12286.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12286.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12287.json
new file mode 100644
index 00000000000..be5f9a92a16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12287.json
@@ -0,0 +1 @@
+{"null": 1.6063777337432468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12288.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12288.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12289.json
new file mode 100644
index 00000000000..8e0b1176b03
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12289.json
@@ -0,0 +1 @@
+{"JARDIANCE": 68.99032974960721, "null": 0.4626010617908807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1229.json
index f66f30500dc..e16554d06e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1229.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1229.json
@@ -1 +1 @@
-{"ABILIFY": 14.74527624607922, "GARDASIL": 8.0695702875848, "OLANZAPINE": 11.509861677372, "SUBOXONE": 17.019392289535624, "null": 1.5889747774186902}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12290.json
new file mode 100644
index 00000000000..f510eed04da
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12290.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 37.38764055173478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12291.json
new file mode 100644
index 00000000000..65610573499
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12291.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 16.991147819062622, "ELIQUIS": 13.782580593129104, "null": 0.7584086883951331}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12292.json
new file mode 100644
index 00000000000..66505e32753
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12292.json
@@ -0,0 +1 @@
+{"JARDIANCE": 72.4486617405501}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12293.json
new file mode 100644
index 00000000000..2848f91ac27
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12293.json
@@ -0,0 +1 @@
+{"JARDIANCE": 70.31054073902767}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12294.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12294.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12295.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12295.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12296.json
new file mode 100644
index 00000000000..04ef4e258cd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12296.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12297.json
new file mode 100644
index 00000000000..9977cee8e6f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12297.json
@@ -0,0 +1 @@
+{"null": 0.800415278061176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12298.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12298.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12299.json
new file mode 100644
index 00000000000..c88c92033f7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12299.json
@@ -0,0 +1 @@
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1.0435464676590605, "MEKINIST": 0.445286821615404, "MELATONIN": 0.2760290493523689, "MENQUADFI": 3.650192534834957, "MENVEO": 2.1288943760301047, "MEPOLIZUMAB": 0.2230899153664171, "METHOTREXATE": 0.4096668198253506, "MICARDIS": 0.7232114731368108, "MICARDISPLUS": 1.4699573921764089, "MIDAZOLAM": 1.7273220098306366, "MIMPARA": 0.4071060817081964, "MIRCERA": 0.9182513271214082, "MIXTARD": 0.8738239942372138, "MMRVAXPRO": 3.334288541485983, "MODERNA": 1.968943501798008, "MULTAQ": 0.2879513243933193, "MULTITRACE4": 52.12932661667173, "MYCOPHENOLATE": 0.2327438408551402, "NAGLAZYME": 1.6359382245313627, "NEULASTA": 0.7991434482286004, "NEXAVAR": 0.2879985655851093, "NIMENRIX": 2.6125895213199795, "NINLARO": 0.3346200868319816, "NIVESTIM": 2.451895991508003, "NORVIR": 0.7770648197871529, "NOT": 0.7238585759646617, "NOVONORM": 0.7798192883183204, "NOVORAPID": 0.4562491308084264, "NOVOSEVEN": 0.3074629575226243, "NOXAFIL": 0.2231026803778202, "NPLATE": 0.224155145302987, "NUCALA": 1.6172194260234587, "OCALIVA": 0.2160775314885235, "OCRELIZUMAB": 0.3641155498313461, "OFEV": 0.058704205681082, "OLANZAPINE": 0.0785965042103663, "OLOPATADINE": 3.0713192100334337, "OMALIZUMAB": 3.7346637040834727, "ONCASPAR": 6.837261656068539, "ONGLYZA": 0.7478406613801, "OPDIVO": 0.1945167185010017, "OPSUMIT": 0.1109292376584873, "OPTIMARK": 0.05414205468716, "ORENCIA": 0.579195783359528, "ORKAMBI": 0.5729475705383767, "OSELTAMIVIR": 1.0852917618698597, "OXYBUTYNIN": 0.6064043899663554, "PANTOPRAZOLE": 0.6546822233786102, "PEGASPARGASE": 2.684179929667882, "PEGASYS": 0.4354848433971557, "PEGINTERFERON": 0.1927006591097064, "PEGINTRON": 0.3077611616676043, "PEMBROLIZUMAB": 0.1949439624421161, "PEMETREXED": 0.2086547137411981, "PERJETA": 0.394573814259853, "PIQRAY": 0.7306207808172505, "PLAVIX": 0.901313713907936, "PLEGRIDY": 0.6842182455695192, "PRADAXA": 0.465295283298086, "PREGABALIN": 0.1420238180534114, "PREVENAR": 2.1140733241702736, "PRIVIGEN": 2.766630145047806, 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0.3987852435910685, "SUFENTANIL": 4.307469041577118, "SUSTIVA": 0.9386522566871688, "SUTENT": 0.0734471317785138, "SYMTUZA": 1.2505537692309785, "SYNAGIS": 0.573644104581268, "SYNFLORIX": 1.3045203780551444, "TAGRISSO": 0.4630847076962781, "TAMIFLU": 1.769058006082852, "TASIGNA": 0.2039591644998961, "TELMISARTAN": 0.6385225399141746, "TEMODAL": 0.8168173470219496, "TEMOZOLOMIDE": 0.366563751918284, "THALIDOMIDE": 0.7013608779009525, "TICAGRELOR": 0.3092027146926586, "TOBRAMYCIN": 0.7828924777113329, "TOCILIZUMAB": 0.6724392049151812, "TORISEL": 0.2232124884016468, "TOUJEO": 1.0514018090775827, "TOVIAZ": 0.2625268468731971, "TOZINAMERAN": 0.8727049771117948, "TRACLEER": 0.0870046752536491, "TRELEGY": 0.3160518980619045, "TREMFYA": 1.280889466838342, "TRESIBA": 0.8370261374577248, "TRIUMEQ": 0.3507326216112515, "TRULICITY": 0.6092586633843694, "TWINRIX": 2.0789420262835465, "UROREC": 2.0177882020773685, "USTEKINUMAB": 0.9206942354524984, "VAXZEVRIA": 0.5524753980300257, "VEKLURY": 0.8007798392483862, "VFEND": 0.1170241862267467, "VIAGRA": 0.0478564278248476, "VICTOZA": 0.6342579257295677, "VIMPAT": 0.1588480933473801, "VIRAMUNE": 0.4400741946658115, "VORICONAZOLE": 0.1565625662987595, "VORTIOXETINE": 1.239157360675207, "VOTRIENT": 0.0551486518578179, "XARELTO": 0.466615132706469, "XELJANZ": 0.194384102436051, "XOLAIR": 6.429978739271183, "XTANDI": 0.1224245895944809, "XYREM": 0.2797982540809596, "YERVOY": 0.1594212644665286, "ZARZIO": 2.557677080224101, "ZELBORAF": 0.4836210193778809, "ZIAGEN": 1.1372829255277617, "ZOSTAVAX": 0.3932590343201556, "ZYLLT": 9.606568970908452, "ZYPREXA": 0.0955689588118582, "null": 2.148325114829092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/123.json
index 889b75a6d38..3bf35f76215 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/123.json
@@ -1 +1 @@
-{"CYTARABINE": 22.86089195551355, "SUTENT": 7.110934820664927}
\ No newline at end of file
+{"null": 2.4842647337053423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1230.json
index 80b79b7882b..5d81cd12640 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1230.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1230.json
@@ -1 +1 @@
-{"COMIRNATY": 1.45751370378527}
\ No newline at end of file
+{"EMPAGLIFLOZIN": 218.7026727542693, "FORXIGA": 68.82891461212704, "JARDIANCE": 271.763662053063, "null": 0.1836080941165072}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12300.json
new file mode 100644
index 00000000000..dfe835f946e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12300.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.6331699430977666}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12301.json
new file mode 100644
index 00000000000..c129282cdbe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12301.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1281968981669783, "null": 0.4065230150002053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12302.json
new file mode 100644
index 00000000000..a98ba942b21
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12302.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.373579197427477, "GARDASIL": 1.4187050566002306, "MODERNA": 2.4439496973921404, "SPIKEVAX": 6.48450616608554, "TOZINAMERAN": 2.203612449146592, "VAXZEVRIA": 0.5769874624054085, "XOLAIR": 3.624366755925291, "null": 0.2615634972625275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12303.json
new file mode 100644
index 00000000000..bd552fc4a5a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12303.json
@@ -0,0 +1 @@
+{"null": 0.6579458467610275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12304.json
new file mode 100644
index 00000000000..033cbe7caf1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12304.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3330514995290652, "VAXZEVRIA": 0.2227585198549244, "null": 2.35093359591709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12305.json
new file mode 100644
index 00000000000..0421fb3fbca
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12305.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 3.762240226695949}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12306.json
new file mode 100644
index 00000000000..fab5ca81e48
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12306.json
@@ -0,0 +1 @@
+{"null": 1.22211340837723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12307.json
new file mode 100644
index 00000000000..43900f8425c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12307.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.3505877853793753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12308.json
new file mode 100644
index 00000000000..4038535c263
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12308.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.103901918852702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12309.json
new file mode 100644
index 00000000000..a1f70ae9a07
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12309.json
@@ -0,0 +1 @@
+{"null": 1.6950053364439617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1231.json
index 7578468c877..8dfc66ef118 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1231.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1231.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1434562071924492}
\ No newline at end of file
+{"COMIRNATY": 0.0372899812564373, "COMPRESSION": 357.265502649812, "EMPAGLIFLOZIN": 46.544787654675865, "FORXIGA": 172.48346928606423, "JARDIANCE": 499.9294475045099, "null": 0.1421647487651155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12310.json
new file mode 100644
index 00000000000..75b3256e7fd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12310.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.754175554808481, "COSENTYX": 4.272452463009635, "OMALIZUMAB": 8.94657287559428, "SIMPONI": 4.786117018636375, "SPIKEVAX": 0.4889402210702717, "TOZINAMERAN": 1.2459221504171936, "VAXZEVRIA": 0.2676557627172827, "XOLAIR": 13.52977861737449, "null": 0.8287803121713035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12311.json
new file mode 100644
index 00000000000..26a63b28d14
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12311.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 15.93467343237572, "COMIRNATY": 0.7072487425718242, "NUCALA": 38.41100752539437, "SYNAGIS": 85.76848509527693, "TOZINAMERAN": 1.29221194615705, "null": 1.2712043595010123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12312.json
new file mode 100644
index 00000000000..a6d65287b72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12312.json
@@ -0,0 +1 @@
+{"null": 2.7886102062597917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12313.json
new file mode 100644
index 00000000000..e0c4da96c12
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12313.json
@@ -0,0 +1 @@
+{"BYDUREON": 2.3898756561778423, "CELLCEPT": 3.159900391833776, "ELIQUIS": 0.6684676374089721, "EVISTA": 20.47846108275617, "FASLODEX": 2.462324573735119, "HUMALOG": 0.9219363901762424, "LANTUS": 1.7978014394378512, "OMALIZUMAB": 4.719583326786492, "PEGASYS": 0.5248362581859599, "SIMPONI": 3.022634013855576, "STELARA": 2.674807731411409, "TRELEGY": 3.343097083018364, "TREMFYA": 6.167129787376299, "XELJANZ": 1.3936043327329823, "XOLAIR": 1.7608612876857372, "null": 4.868383943090629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12314.json
new file mode 100644
index 00000000000..faa6172baa6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12314.json
@@ -0,0 +1 @@
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12315.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12315.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12316.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12316.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12317.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12317.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12318.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12318.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12319.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12319.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1232.json
index 2673f9c078f..cea6c5a3154 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1232.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1232.json
@@ -1 +1 @@
-{"ABILIFY": 64.09943774249, "BUDESONIDE": 41.0277891035544}
\ No newline at end of file
+{"COMIRNATY": 0.4208480736376566, "null": 2.369337856907957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12320.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12320.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12321.json
new file mode 100644
index 00000000000..b8d204088fa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12321.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.4551578737629358, "null": 1.2866773372129747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12322.json
new file mode 100644
index 00000000000..df278c44c73
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12322.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.5096114856378169, "SPIKEVAX": 0.7378179248697322, "TOZINAMERAN": 1.084672140080639, "null": 1.5856652159589897}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12323.json
new file mode 100644
index 00000000000..5421cb064cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12323.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.0933155765940434, "null": 0.3739339492136918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12324.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12324.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12325.json
new file mode 100644
index 00000000000..1fc0dbaa1f9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12325.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.173785004343993, "null": 7.557721569785323}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12326.json
new file mode 100644
index 00000000000..7aa318812a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12326.json
@@ -0,0 +1 @@
+{"null": 0.9505518610027304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12327.json
new file mode 100644
index 00000000000..b2555cd369e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12327.json
@@ -0,0 +1 @@
+{"ARAVA": 0.7235337580308704, "COMIRNATY": 0.2033043830461072, "CYMBALTA": 5.1397489357570825, "ELIQUIS": 6.65978960048534, "SUBOXONE": 16.933909194533, "null": 1.566699439322753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12328.json
new file mode 100644
index 00000000000..828a4436e4a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12328.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5632428806805169, "null": 1.4022627324507566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12329.json
new file mode 100644
index 00000000000..8ccc7b2bc2e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12329.json
@@ -0,0 +1 @@
+{"null": 1.5365841720830886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1233.json
index 2ff15c45981..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1233.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1233.json
@@ -1 +1 @@
-{"AFINITOR": 3.9177210908273854, "AIMOVIG": 3.243493863060225, "COSENTYX": 4.893033449740591, "ELIQUIS": 1.0832084760611678, "ENTYVIO": 6.072757220540931, "HUMIRA": 6.146801776798209, "IBRANCE": 1.302889997262647, "KEPPRA": 1.0825282605852262, "PLAVIX": 1.7991060904771636, "SUTENT": 1.8954888783826576, "TOZINAMERAN": 1.2614781071132823, "TRULICITY": 3.267803353671958, "XELJANZ": 11.483806760524454, "null": 1.1892198270602472}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12330.json
new file mode 100644
index 00000000000..2ec0b30f8e3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12330.json
@@ -0,0 +1 @@
+{"ADEMPAS": 9.06019176767264, "CICATRIZANTS": 640.7550590872742, "COMIRNATY": 1.3336236775204544, "ELIQUIS": 2.8062205198555747, "ESMYA": 258.4913001725645, "FENTANYL": 1.1659830763972496, "GARDASIL": 0.5718965506200149, "MODERNA": 5.110606431904274, "PEGASYS": 0.4317804763597282, "PLAVIX": 2.4604278417703065, "RYEQO": 229.40645517067435, "SPIKEVAX": 0.4019313023662388, "TAMIFLU": 1.9976526762123283, "TOZINAMERAN": 1.1426463943428138, "VAXZEVRIA": 0.3992539112460043, "XARELTO": 11.54904791316683, "null": 1.539511726811922}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12331.json
new file mode 100644
index 00000000000..a2d8b7c0cc2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12331.json
@@ -0,0 +1 @@
+{"GONALF": 653.7823168535034, "null": 11.00151411724377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12332.json
new file mode 100644
index 00000000000..4d1ab74126c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12332.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7083571866281364, "null": 3.632688893414892}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12333.json
new file mode 100644
index 00000000000..7a9c8532d51
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12333.json
@@ -0,0 +1 @@
+{"BUPIVACAINE": 244.1697748862151, "FENTANYL": 21.03325875810427, "null": 1.730602438962327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12334.json
new file mode 100644
index 00000000000..7041f4e3460
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12334.json
@@ -0,0 +1 @@
+{"null": 0.6598614144250611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12335.json
new file mode 100644
index 00000000000..3c99b1d26ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12335.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.969330260337686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12336.json
new file mode 100644
index 00000000000..a96a50dd56c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12336.json
@@ -0,0 +1 @@
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12337.json
new file mode 100644
index 00000000000..9ab844cc8ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12337.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3931613700359187, "DOCETAXEL": 3.558386868311663, "ELIQUIS": 0.8926008900238184, "ESMYA": 213.51712604834225, "EVISTA": 10.591473603925976, "GARDASIL": 0.9276766861294802, "IBRANCE": 1.015824582819207, "JANUMET": 2.486599150075654, "JANUVIA": 2.2353113238085918, "LANTUS": 0.8193439500005788, "RYEQO": 107.13312254126102, "SIMPONI": 4.042486266589252, "SOLIRIS": 2.7883942408498053, "SPIKEVAX": 0.2469192650658083, "STELARA": 1.1853551281327392, "TOZINAMERAN": 0.5866688868498485, "VAXZEVRIA": 0.163051741512011, "XELJANZ": 1.4579686317141465, "null": 1.6713027118792465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12338.json
new file mode 100644
index 00000000000..13552d775de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12338.json
@@ -0,0 +1 @@
+{"ESMYA": 9645.11397923189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12339.json
new file mode 100644
index 00000000000..91acf3c60f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12339.json
@@ -0,0 +1 @@
+{"DOCETAXEL": 92.37019843880036, "VOTRIENT": 79.10750355765147, "null": 0.5137590138209702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1234.json
index 3787b2b772d..17f2ab177a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1234.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1234.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 28.60412308755833, "CELLCEPT": 39.87411581662972, "CICLOSPORIN": 19.65715534366673, "JAKAVI": 62.51719957612444, "MYCOPHENOLATE": 64.15577438979065, "VFEND": 15.418936800221308}
\ No newline at end of file
+{"null": 1.1639063761139952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12340.json
new file mode 100644
index 00000000000..6bd8b0e1018
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12340.json
@@ -0,0 +1 @@
+{"null": 0.8825139090080125}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12341.json
new file mode 100644
index 00000000000..5cd728aa338
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12341.json
@@ -0,0 +1 @@
+{"ESMYA": 5290.646315414552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12342.json
new file mode 100644
index 00000000000..8352dc7b27c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12342.json
@@ -0,0 +1 @@
+{"null": 0.7119897356285397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12343.json
new file mode 100644
index 00000000000..cd6b49cdae7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12343.json
@@ -0,0 +1 @@
+{"null": 0.7127343957588432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12344.json
new file mode 100644
index 00000000000..6a009891053
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12344.json
@@ -0,0 +1 @@
+{"COMIRNATY": 8.000411471654123, "MODERNA": 7.186007053708341, "SPIKEVAX": 2.148445097897425, "TOZINAMERAN": 0.9956906268088452, "VAXZEVRIA": 0.2853698746442519, "null": 0.3463224259163422}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12345.json
new file mode 100644
index 00000000000..dca6a956fcb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12345.json
@@ -0,0 +1 @@
+{"null": 3.857120493859071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12346.json
new file mode 100644
index 00000000000..b5d00aeb776
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12346.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5501186530353052, "ESMYA": 118.51616196599598, "EVISTA": 47.03134338984493, "HUMIRA": 9.1013026752956, "TOZINAMERAN": 0.9072617107542978, "null": 1.4211562296193618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12347.json
new file mode 100644
index 00000000000..e3f922d9c97
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12347.json
@@ -0,0 +1 @@
+{"FORSTEO": 14.07737883444102, "null": 1.0998399091416058}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12348.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12348.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12349.json
new file mode 100644
index 00000000000..46bb14fddc9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12349.json
@@ -0,0 +1 @@
+{"MISOPROSTOL": 1028.3502611416975, "null": 9.56476657973407}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1235.json
index eec02b2d9b3..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1235.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1235.json
@@ -1 +1 @@
-{"null": 4.000509736211133}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12350.json
new file mode 100644
index 00000000000..a0ff011840b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12350.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.495090493339423, "SPIKEVAX": 1.828547481735443, "TOZINAMERAN": 1.9917950539604568, "VAXZEVRIA": 0.589402607529711, "null": 0.5363116947743248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12351.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12351.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12352.json
new file mode 100644
index 00000000000..38b1c6df95d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12352.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.89511937733927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12353.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12353.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12354.json
new file mode 100644
index 00000000000..b6bd75bbf65
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12354.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.8353522994753159, "ARAVA": 0.3880792845001697, "AUBAGIO": 0.6344340332653664, "AVASTIN": 1.5621162736269432, "AZATHIOPRINE": 2.245377019003013, "BEOVU": 310.5659431194356, "BEVACIZUMAB": 1.5780036715845611, "BINIMETINIB": 25.963781361970856, "BRAFTOVI": 22.6732421501873, "BROLUCIZUMAB": 142.12030696636904, "CELLCEPT": 1.044207415784135, "CICLOSPORIN": 1.9463396492375304, "CIDOFOVIR": 50.39468728080397, "CIMZIA": 8.99208146113299, "COBIMETINIB": 29.866612985821803, "COMIRNATY": 0.3941919710240246, "COSENTYX": 10.971662889532276, "COTELLIC": 32.431906243672366, "DABRAFENIB": 35.17084728831189, "ENBREL": 1.721041310598375, "ENTYVIO": 3.564730332225373, "EYLEA": 98.49983055842354, "GARDASIL": 0.8950577329175179, "HUMIRA": 5.916080670120188, "IPILIMUMAB": 10.417910022718075, "KEYTRUDA": 4.246042284750102, "MEKINIST": 28.60635493784832, "METHOTREXATE": 1.0247053754486453, "MYCOPHENOLATE": 5.969201817680083, "NEVANAC": 14.661846641593494, "NEXAVAR": 0.4791185284694413, "NORVIR": 7.044802104637939, "OPDIVO": 7.802749831210593, "PEGASYS": 0.3733625192269386, "PEGINTRON": 0.9994776880219242, "PEMBROLIZUMAB": 3.4373673442543686, "ROACTEMRA": 1.5707751416629556, "SHINGRIX": 1.3600598924760583, "SIMPONI": 8.091165755975192, "SPIKEVAX": 0.1816834134939224, "STELARA": 1.5385734431429603, "TAFINLAR": 33.144610733618265, "TOZINAMERAN": 0.8813326761727241, "VAXZEVRIA": 0.1498670014417141, "VEMURAFENIB": 21.973604597435383, "XELJANZ": 0.606673487552784, "YERVOY": 5.682803675190282, "ZELBORAF": 14.33562206950657, "ZOSTAVAX": 1.0171542146388008, "null": 0.4964904804041546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12355.json
new file mode 100644
index 00000000000..faa6172baa6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12355.json
@@ -0,0 +1 @@
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12356.json
new file mode 100644
index 00000000000..fc10060c978
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12356.json
@@ -0,0 +1 @@
+{"null": 0.9090954767196192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12357.json
new file mode 100644
index 00000000000..c0df0942d2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12357.json
@@ -0,0 +1 @@
+{"null": 3.203720978667747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12358.json
new file mode 100644
index 00000000000..7be4ad05ba9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12358.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.153587821749067, "null": 0.7816763579197556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12359.json
new file mode 100644
index 00000000000..8a77578abcf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12359.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 2.0239796708570688, "COMIRNATY": 0.9770638694582804, "DEXAMETHASONE": 5.786014545337896, "KEYTRUDA": 1.837853473132168, "SPIKEVAX": 0.9460089741076524, "TOZINAMERAN": 1.6062509016476236, "VAXZEVRIA": 0.4502229844100536, "ZOSTAVAX": 4.506738692900286, "null": 0.7629922752209063}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1236.json
index ff6cc8931f0..6091bd7ad19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1236.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1236.json
@@ -1 +1 @@
-{"INSULIN": 26.47057963704047, "SPIKEVAX": 1.355323052878493}
\ No newline at end of file
+{"AUBAGIO": 23.5808206978337, "COMIRNATY": 1.5469762677382577, "VAXZEVRIA": 0.4280078198505356, "null": 0.7390848484415319}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12360.json
new file mode 100644
index 00000000000..78e151bf6d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12360.json
@@ -0,0 +1 @@
+{"CIMZIA": 1.9657495814055357, "COMIRNATY": 0.4601914328675445, "CYMBALTA": 1.0177104157581744, "GARDASIL": 13.765638125900646, "INFANRIX": 31.808213504448755, "MMRVAXPRO": 12.360323281803293, "PREVENAR": 59.30392124658279, "SPIKEVAX": 2.7513574196908603, "TWINRIX": 99.80802683284112, "VAXZEVRIA": 0.1099258798758447, "null": 1.3118347104869634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12361.json
new file mode 100644
index 00000000000..77c08de94e4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12361.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6638655560613338, "GARDASIL": 11.796504318858885, "MMRVAXPRO": 7.308917758624931, "ROTATEQ": 23.7675830682938, "SPIKEVAX": 0.441028522274594, "TOZINAMERAN": 29.29445513605909, "VAXZEVRIA": 0.8098239747912618, "ZOSTAVAX": 11.507696430582966, "null": 0.1147095245445784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12362.json
new file mode 100644
index 00000000000..75dbf2ec3d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12362.json
@@ -0,0 +1 @@
+{"ADVAGRAF": 0.5421911450754785, "AZATHIOPRINE": 0.086506077171615, "BEXSERO": 0.6189776345867598, "CELLCEPT": 0.0487037974980903, "COMIRNATY": 10.486846626870584, "CYMBALTA": 0.0083263644740092, "ECULIZUMAB": 1.2911582197969904, "GARDASIL": 0.4619038208621952, "HUMIRA": 0.072207070906866, "IBUPROFEN": 0.0340963609578846, "JANSSEN": 7.943152040062156, "JCOVDEN": 0.628248871742028, "LYRICA": 0.0549915931937353, "MENVEO": 0.4832703581629601, "MEPOLIZUMAB": 0.0399270556590297, "MERCK": 3.301923646555068, "MMRVAXPRO": 0.1886741663956197, "MODERNA": 0.2735843540240357, "NIMENRIX": 0.065522100234229, "NOT": 0.4237070422522603, "NUCALA": 0.0644657993898796, "RINVOQ": 0.0819290620529612, "RITUXIMAB": 0.088940922067323, "ROTARIX": 1.5530465705793173, "ROTATEQ": 4.128893392982556, "SHINGRIX": 7.835836030644842, "SILGARD": 1.5276103578829645, "SPIKEVAX": 0.9392119911084558, "SYNFLORIX": 1.662612088247819, "TOZINAMERAN": 1.5013992667287517, "TWINRIX": 0.282139478935369, "VAXZEVRIA": 2.1519002182290574, "ZOSTAVAX": 9.144615343090909, "null": 0.1834693640737301}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12363.json
new file mode 100644
index 00000000000..535967487e9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12363.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.7124230871668014, "SPIKEVAX": 1.0149663405843583, "VAXZEVRIA": 1.8272748496461733, "null": 0.7955638368105583}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12364.json
new file mode 100644
index 00000000000..6dc57213602
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12364.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.367091894156062, "SPIKEVAX": 3.3905194389852964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12365.json
new file mode 100644
index 00000000000..3608196bd1d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12365.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.126837169330628, "VAXZEVRIA": 3.979652304334648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12366.json
new file mode 100644
index 00000000000..a04436610cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12366.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.310101819935221, "SPIKEVAX": 2.948621457100035, "TOZINAMERAN": 6.413074860368288, "VAXZEVRIA": 3.810908991854558, "null": 0.0256547225554072}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12367.json
new file mode 100644
index 00000000000..ec477856abc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12367.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7119362452974769, "GARDASIL": 10.109298148657416, "MENVEO": 149.46037768367236, "MODERNA": 12.33439933654798, "SPIKEVAX": 1.8403742887346768, "TOZINAMERAN": 7.699776531801237, "VAXZEVRIA": 0.7646709359171635, "ZOSTAVAX": 8.732929343112268, "null": 0.4808721108724748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12368.json
new file mode 100644
index 00000000000..80866e62ce0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12368.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.7856817964749263, "SPIKEVAX": 2.130150629721304, "VAXZEVRIA": 1.8178807887380788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12369.json
new file mode 100644
index 00000000000..34b720a0832
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12369.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.7165341038425728, "SPIKEVAX": 2.469002257878272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1237.json
index 1482483133d..4c5ffd12c5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1237.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1237.json
@@ -1 +1 @@
-{"null": 1.4863998810893884}
\ No newline at end of file
+{"null": 0.9316421351246048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12370.json
new file mode 100644
index 00000000000..7042fb79c9d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12370.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.0130939076213488, "SPIKEVAX": 2.8373615110011308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12371.json
new file mode 100644
index 00000000000..eb79105232f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12371.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.319709517087196, "HEXYON": 260.6918853920437, "MMRVAXPRO": 42.60356141210312, "SPIKEVAX": 3.8329782106008192, "TOZINAMERAN": 2.862095898483448, "VAXZEVRIA": 1.2020721569164512, "null": 0.0598059031396094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12372.json
new file mode 100644
index 00000000000..05e756a154b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12372.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.3886811124851635, "MODERNA": 4.526527069205722, "SPIKEVAX": 3.581414604118077, "TOZINAMERAN": 1.7803637510293069, "VAXZEVRIA": 8.16793278801389, "null": 0.0082136980802303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12373.json
new file mode 100644
index 00000000000..029bb595b12
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12373.json
@@ -0,0 +1 @@
+{"MMRVAXPRO": 188.5578073697158}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12374.json
new file mode 100644
index 00000000000..44be04b4d4c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12374.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.902165022523647, "SPIKEVAX": 3.098855753053404, "VAXZEVRIA": 0.9047300295801036}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12375.json
new file mode 100644
index 00000000000..d629b252ae7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12375.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1401698742653894, "HEXYON": 551.143739752107, "MMRVAXPRO": 110.94639226178272, "MODERNA": 16.21391064668421, "SPIKEVAX": 2.1560321186073264, "VAXZEVRIA": 0.4903619367710655, "null": 0.119338446854473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12376.json
new file mode 100644
index 00000000000..f89508c5383
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12376.json
@@ -0,0 +1 @@
+{"BEXSERO": 3.942080530266587, "COMIRNATY": 4.216199733982142, "FLUCELVAX": 6.599531224063584, "GARDASIL": 0.6354227998511838, "HEXYON": 14.862515432037831, "HUMIRA": 0.1146922541922402, "INFANRIX": 1.7960991784337648, "MENVEO": 10.109563158396892, "MMRVAXPRO": 3.3889141175212, "MODERNA": 4.8991115299175645, "NIMENRIX": 4.978503019292488, "PREVENAR": 3.678785122755304, "ROTATEQ": 0.3499668105595506, "SHINGRIX": 3.1190925999891164, "SPIKEVAX": 9.48038970395938, "TOZINAMERAN": 1.4944423246011491, "VAXZEVRIA": 1.3431520010090363, "ZOSTAVAX": 0.748851288002448, "null": 0.0705375695410278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12377.json
new file mode 100644
index 00000000000..0421fb3fbca
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12377.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 3.762240226695949}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12378.json
new file mode 100644
index 00000000000..208217fd8b6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12378.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2851704740472947, "GARDASIL": 5.39448124161537, "HEXYON": 1511.2063477437218, "INFANRIX": 141.45240558382972, "MMRVAXPRO": 308.6592987071166, "PREVENAR": 114.03315106091456, "TWINRIX": 30.439838249201856, "VAXZEVRIA": 0.1819239465086258, "null": 0.1714169323570606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12379.json
new file mode 100644
index 00000000000..396045e3819
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12379.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.797659734049902, "MMRVAXPRO": 1.9547670086693392, "MODERNA": 12.779116524115253, "SHINGRIX": 1.799160094004278, "SPIKEVAX": 2.2955020473997525, "TOZINAMERAN": 0.2558618526942592, "VAXZEVRIA": 4.335639057343761, "null": 0.037144246837921}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1238.json
index 161dc2c562f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1238.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1238.json
@@ -1 +1 @@
-{"null": 2.3725271003843598}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12380.json
new file mode 100644
index 00000000000..7859f67575a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12380.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.298182732894576, "GARDASIL": 2.211264244502202, "MEPOLIZUMAB": 18.39415335139857, "NIMENRIX": 17.04662020251099, "SPIKEVAX": 2.480874280352384, "TOZINAMERAN": 7.213053643834584, "VAXZEVRIA": 0.691579371369601, "null": 0.0361244268628732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12381.json
new file mode 100644
index 00000000000..fead91ccdb5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12381.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.497140044852421, "SPIKEVAX": 5.340100465051638, "VAXZEVRIA": 1.1563674077334152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12382.json
new file mode 100644
index 00000000000..f9c294f4fa0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12382.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.5454564037404284, "SPIKEVAX": 3.172077340616561, "TOZINAMERAN": 2.9000844891473387, "VAXZEVRIA": 3.970763606307533}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12383.json
new file mode 100644
index 00000000000..70af34fff2f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12383.json
@@ -0,0 +1 @@
+{"HEXYON": 1036.1351899356696, "MMRVAXPRO": 300.3033382253412, "PREVENAR": 341.6062232579544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12384.json
new file mode 100644
index 00000000000..fecdd1faeb3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12384.json
@@ -0,0 +1 @@
+{"HEXYON": 1777.208906920939, "MMRVAXPRO": 179.99183316614966}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12385.json
new file mode 100644
index 00000000000..7d3992e8931
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12385.json
@@ -0,0 +1 @@
+{"COMIRNATY": 6.993749150244167, "SPIKEVAX": 1.6206080107139844, "TOZINAMERAN": 6.992759846729011, "VAXZEVRIA": 1.0603417283559988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12386.json
new file mode 100644
index 00000000000..75e17230766
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12386.json
@@ -0,0 +1 @@
+{"BEXSERO": 12.189139968881756, "COMIRNATY": 3.6141472883530215, "GARDASIL": 1.6167795221075527, "MENVEO": 38.6015465631628, "MMRVAXPRO": 1.8441809252495849, "MODERNA": 14.449464873076607, "NIMENRIX": 8.306726101960674, "PREVENAR": 7.050810175884354, "SHINGRIX": 2.6586826396203564, "SPIKEVAX": 4.357639986696224, "TOZINAMERAN": 1.6334938691870493, "VAXZEVRIA": 1.9780130342681617, "ZOSTAVAX": 0.7633025798460092, "null": 0.2284770086565736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12387.json
new file mode 100644
index 00000000000..2b3ff3aa00c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12387.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.919859546216306, "SPIKEVAX": 5.793759033163043, "TOZINAMERAN": 3.33710409940118, "VAXZEVRIA": 2.428307199803139, "null": 0.1748841663745269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12388.json
new file mode 100644
index 00000000000..f187bcb2e33
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12388.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.948383240996125, "FLUCELVAX": 9.92107956309956, "GARDASIL": 0.2849686647422109, "MENVEO": 8.020744994118138, "MMRVAXPRO": 0.9827403079739192, "MODERNA": 105.10557487413904, "NIMENRIX": 9.287959741683382, "NOT": 2.5961379245385032, "SHINGRIX": 5.726298444507652, "SPIKEVAX": 4.049259034197164, "TOZINAMERAN": 0.94917094485694, "VAXZEVRIA": 1.4662335488908254, "ZOSTAVAX": 0.3620788291911295, "null": 0.1801803816359564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12389.json
new file mode 100644
index 00000000000..f7fc536c8fc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12389.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.893751629401894, "VAXZEVRIA": 2.069528423028377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1239.json
index b629e29d027..5261f26c6c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1239.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1239.json
@@ -1 +1 @@
-{"null": 4.121242872845213}
\ No newline at end of file
+{"TERIPARATIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12390.json
new file mode 100644
index 00000000000..88c585f3f45
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12390.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.466119054157579, "HEXYON": 229.8750314901758, "MMRVAXPRO": 37.3490613321216, "SPIKEVAX": 4.433093113123713, "TOZINAMERAN": 1.975293865446003, "VAXZEVRIA": 1.364602030869983, "null": 0.0768126698172765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12391.json
new file mode 100644
index 00000000000..891f954a8d6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12391.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.094124968275052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12392.json
new file mode 100644
index 00000000000..8b564303e08
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12392.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.1962597357609708, "MODERNA": 48.33606911024823, "NIMENRIX": 12.758099906039234, "SPIKEVAX": 5.053459614222733, "VAXZEVRIA": 0.9599130269821088, "null": 0.0512407978672143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12393.json
new file mode 100644
index 00000000000..b1619baae3e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12393.json
@@ -0,0 +1 @@
+{"COMIRNATY": 6.322604324826986, "SPIKEVAX": 1.3071281457412125, "VAXZEVRIA": 0.90346738752329}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12394.json
new file mode 100644
index 00000000000..1534f1b7ba3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12394.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.5635669983705, "SPIKEVAX": 2.941504048812252, "TOZINAMERAN": 3.714374586639627, "VAXZEVRIA": 1.6950254610850624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12395.json
new file mode 100644
index 00000000000..b83db6f836a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12395.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.359083487324133, "MODERNA": 6.832184473845358, "SPIKEVAX": 2.888851514119865, "TOZINAMERAN": 1.647305864463248, "VAXZEVRIA": 2.467958485462502, "null": 0.0202972266020021}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12396.json
new file mode 100644
index 00000000000..5aa7d52c14b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12396.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.612035948431808, "MENVEO": 65.08829983941715, "SHINGRIX": 4.960741404371193, "SPIKEVAX": 5.130882669767635, "VAXZEVRIA": 0.8597655036562653, "null": 0.059241370042486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12397.json
new file mode 100644
index 00000000000..084f53f32d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12397.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 4.27980290036856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12398.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12398.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12399.json
new file mode 100644
index 00000000000..15538326f41
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12399.json
@@ -0,0 +1 @@
+{"COMIRNATY": 11.675879322485272, "MODERNA": 37.69888942720888, "NIMENRIX": 2.793364032369446, "SPIKEVAX": 4.449248712217094, "TOZINAMERAN": 0.1685730063227093, "VAXZEVRIA": 0.1760552243525363, "null": 0.0174792560073569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/124.json
index cb22c060299..6996d4c7396 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/124.json
@@ -1 +1 @@
-{"ABIRATERONE": 98.12491820156411, "ADENURIC": 13.710295525165574, "ALIMTA": 2.617058852760312, "AVANDAMET": 60.71043296661498, "AVANDIA": 38.27116578786335, "AVASTIN": 1.3773254685779397, "BRILIQUE": 14.19134159769352, "CAPECITABINE": 3.0280353143031533, "CHAMPIX": 1.7080665062020222, "CLOPIDOGREL": 4.998620401909475, "DEXAMETHASONE": 1.1835746679943109, "ICLUSIG": 7.110595663817508, "INLYTA": 2.188402574626931, "JAKAVI": 2.21174276184592, "KYPROLIS": 8.319614759999924, "MICARDIS": 1.6860734791382783, "NEXAVAR": 3.2599777359171687, "NILOTINIB": 19.27922283498472, "NPLATE": 3.087925402979168, "NUCALA": 1.9155821303159617, "OFEV": 4.000394916872363, "OLANZAPINE": 1.7108363848260733, "PLAVIX": 3.9878396818999975, "RITUXIMAB": 1.1555374959404918, "ROACTEMRA": 1.729347529908949, "STELARA": 1.670881039795676, "STIVARGA": 1.0248813842411288, "TASIGNA": 5.4828793947312695, "TICAGRELOR": 4.833472647267703, "VIAGRA": 1.8409092516002703}
\ No newline at end of file
+{"CICLOSPORIN": 34.137733172709574, "null": 0.6967559409027245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1240.json
index cc583f9a2d3..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1240.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1240.json
@@ -1 +1 @@
-{"BRILIQUE": 7.455671547734895, "BUDESONIDE": 2.038666637566187, "LEVETIRACETAM": 4.518278149119372, "SUTENT": 1.5649603011364035, "null": 4.531337811583909}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12400.json
new file mode 100644
index 00000000000..0d41f04856d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12400.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.89483429244972, "SPIKEVAX": 14.482614676282225, "VAXZEVRIA": 0.6460114444551593}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12401.json
new file mode 100644
index 00000000000..5a203f1fc6d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12401.json
@@ -0,0 +1 @@
+{"BEXSERO": 19.86238508523226, "COMIRNATY": 2.666952652011448, "GARDASIL": 1.4315205969265132, "MMRVAXPRO": 1.4094333641844965, "MODERNA": 10.830665678169686, "NIMENRIX": 2.783140459107506, "OCRELIZUMAB": 5.056320971328449, "SPIKEVAX": 2.217498772266236, "TOZINAMERAN": 10.51729206860865, "VAXZEVRIA": 3.2280635335971284, "null": 0.0551992204764146}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12402.json
new file mode 100644
index 00000000000..46a061fc174
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12402.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.1132345412983655, "GARDASIL": 0.4193976053892196, "MODERNA": 7.109649302215687, "SHINGRIX": 1.7275385378146828, "SPIKEVAX": 5.574206071555064, "TOZINAMERAN": 2.7054382442593417, "VAXZEVRIA": 1.8692841631778077, "null": 0.0194057397765053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12403.json
new file mode 100644
index 00000000000..442c1a79e5d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12403.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.756547186484228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12404.json
new file mode 100644
index 00000000000..bff9a703c81
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12404.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.572165599670352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12405.json
new file mode 100644
index 00000000000..4133bfd3d81
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12405.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.085496031126291, "GARDASIL": 8.801688959630235, "MMRVAXPRO": 19.86285678898617, "SPIKEVAX": 0.764566012725982, "TOZINAMERAN": 2.616695311142516, "VAXZEVRIA": 1.125379740676704, "null": 0.3019791850108914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12406.json
new file mode 100644
index 00000000000..421a50dfe3e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12406.json
@@ -0,0 +1 @@
+{"BEXSERO": 7.956006488224018, "COMIRNATY": 5.74941481186386, "GARDASIL": 0.5280614503792078, "INFANRIX": 4.47265674319959, "MENVEO": 47.43242298537725, "MMRVAXPRO": 6.734524941574374, "MODERNA": 12.561405836200535, "NIMENRIX": 8.988282594334297, "ROTATEQ": 1.6913601865666728, "SHINGRIX": 2.377395474010266, "SPIKEVAX": 4.693628928080684, "TOZINAMERAN": 0.3787587604258267, "VAXZEVRIA": 1.339011398391793, "ZOSTAVAX": 0.5013285971443581, "null": 0.1321708676328826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12407.json
new file mode 100644
index 00000000000..bbfb7e35090
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12407.json
@@ -0,0 +1 @@
+{"BEXSERO": 0.9192853113586856, "BRINTELLIX": 0.1763114110705477, "BYDUREON": 0.0817695414220989, "COMIRNATY": 6.904037495364273, "ELASOMERAN": 2.397686094985078, "FENDRIX": 4.011770971260221, "FLUCELVAX": 3.615193606358792, "GARDASIL": 0.633922307571908, "HEXYON": 1.6167098395528372, "HUMIRA": 0.4002130590834338, "HYDROCORTISONE": 0.0911919051134899, "INFANRIX": 0.6328119822640621, "JCOVDEN": 0.8740888875659446, "MENVEO": 2.1860909693921133, "MEPOLIZUMAB": 0.0303023220983875, "MMRVAXPRO": 1.8696885730490196, "MODERNA": 8.839697699495801, "NIMENRIX": 2.037475371541233, "NOT": 0.1154501705676136, "OCRELIZUMAB": 0.1927859445631387, "PREVENAR": 0.388261396644363, "RINVOQ": 0.2175398520989352, "SHINGRIX": 1.6583977321153704, "SPIKEVAX": 3.60540702191016, "STELARA": 0.0637107927696265, "TOZINAMERAN": 2.0369918608994326, "TWINRIX": 0.4978329351961894, "VAXZEVRIA": 2.80636773363106, "ZOSTAVAX": 0.1983898591082459, "null": 0.0252265380583052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12408.json
new file mode 100644
index 00000000000..624509b0226
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12408.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.6713001992011205, "SPIKEVAX": 2.3222269398945103, "VAXZEVRIA": 0.9393081827840992, "null": 0.2587107406789603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12409.json
new file mode 100644
index 00000000000..4fa115c6df6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12409.json
@@ -0,0 +1 @@
+{"COMIRNATY": 7.619313059900217, "MODERNA": 13.653520435062642, "SPIKEVAX": 2.191809999881306, "TOZINAMERAN": 2.465957856004791, "VAXZEVRIA": 1.57190174814665, "null": 0.0243069011800586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1241.json
index 4bff184371e..7686580e6eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1241.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1241.json
@@ -1 +1 @@
-{"ADENURIC": 1.230039627418245, "ALEMTUZUMAB": 1.2936925280440204, "ALISKIREN": 1.333559355936418, "ANAGRELIDE": 7.792302572196986, "ANGIOX": 3.2330281139724, "APROVEL": 4.702164001275087, "BETA": 9.180797974562536, "BEXTRA": 3.4062872234417187, "BLINDED": 8.381657945700816, "BORTEZOMIB": 1.6728848297318957, "BRIDION": 38.41641357843466, "BRILIQUE": 5.438509389358259, "BUPIVACAINE": 5.34914881292289, "CARFILZOMIB": 1.0049538191247074, "CERTAGEN": 132.991069893136, "COAPROVEL": 4.847306922936101, "COMBIVIR": 1.0572352080519494, "DABIGATRAN": 7.710796698915945, "DACLATASVIR": 3.49247399722273, "DAKLINZA": 2.1425306527845995, "DEXAMETHASONE": 1.6959151413584803, "DEXDOR": 62.28228441829533, "DEXMEDETOMIDINE": 21.72925237247872, "EBIXA": 13.996402436069182, "EMPAGLIFLOZIN": 2.494857303150518, "ENTRESTO": 1.0236377222009465, "EPCLUSA": 1.5972092884344204, "ESOMEPRAZOLE": 1.1672066601417586, "EXELON": 14.38727758371703, "EXFORGE": 1.4149210744284344, "FENTANYL": 6.765244552111261, "FESOTERODINE": 20.254344539294195, "GAZYVARO": 1.1936529926287855, "GLUCAGON": 11.913955633636368, "HARVONI": 2.1070025351553063, "HEMANGIOL": 16.132973088012957, "HYDROCHLOROTHIAZIDE": 1.7303165782830143, "IBUPROFEN": 1.3058166031857577, "INFANRIX": 2.021709735785601, "INTEGRILIN": 2.885982502303168, "IRBESARTAN": 3.619958624820904, "IRON": 1.2404790039782188, "IVABRADINE": 12.921994780117796, "KALETRA": 2.106316986404012, "KARVEZIDE": 4.744831603235164, "KEPPRA": 1.4799579666764842, "KYPROLIS": 1.3764254574153238, "LACOSAMIDE": 2.6396312013192538, "LEMTRADA": 7.211005267683478, "LEVETIRACETAM": 1.1564364761210135, "LYRICA": 1.2543642095823264, "MEMANTINE": 3.785151795454595, "MICARDIS": 3.81211456152521, "MIDAZOLAM": 6.083821605242825, "MULTAQ": 5.644514539408192, "NOVONORM": 1.4888824693037763, "NOXAFIL": 1.9373620802575229, "OLANZAPINE": 1.558940120010498, "PANTOPRAZOLE": 1.0035920248281012, "PAXLOVID": 4.522539105533408, "PRADAXA": 1.527589461230556, "PREGABALIN": 1.2662808715604632, "PROCORALAN": 20.307188511289677, "PROPRANOLOL": 13.260995512949169, "RANEXA": 3.3454798236021865, "RANOLAZINE": 1.2693191135283752, "RAPISCAN": 14.424446752245444, "RASILEZ": 2.4043878779475967, "REGADENOSON": 15.877785184013655, "REMDESIVIR": 15.6021801938931, "RIOCIGUAT": 17.29285774469415, "RIVAROXABAN": 3.019722875778368, "SAXAGLIPTIN": 11.208902794701231, "SIFROL": 1.0679666895533202, "SILDENAFIL": 3.032438785622027, "SOFOSBUVIR": 8.356652730122704, "SOMAVERT": 8.070583443582892, "SOVALDI": 1.9027920007553591, "SPIRONOLACTONE": 4.588331015162281, "SUFENTANIL": 6.111201408025092, "SUGAMMADEX": 22.04753909079276, "SYCREST": 1.2120927877815355, "SYNAGIS": 2.585808935800016, "TELMISARTAN": 4.090960621042076, "THALIDOMIDE": 4.76426431671323, "TICAGRELOR": 1.2981552038251591, "VALSARTAN": 1.8132476256723773, "VEKLURY": 27.1104221545622, "VFEND": 1.278508087058767, "VILDAGLIPTIN": 2.7250977614074783, "VIMPAT": 6.331013798538694, "XALKORI": 7.817601448485394, "XARELTO": 1.5108768683639249, "XYREM": 1.109175955609703, "ZONISAMIDE": 2.557206636240675, "ZYPADHERA": 1.0278739852276624, "ZYPREXA": 1.2610048014923494, "null": 4.139522565604644}
\ No newline at end of file
+{"ROTATEQ": 2708.880104596388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12410.json
new file mode 100644
index 00000000000..f303a0ded5b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12410.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.3668260425435073, "SPIKEVAX": 16.57793478548532, "VAXZEVRIA": 0.5596464003010996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12411.json
new file mode 100644
index 00000000000..d2863fab5b7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12411.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.398426831029988, "FLUCELVAX": 3.2552832468659143, "GARDASIL": 0.3350120638821842, "HEXYON": 35.2598687676903, "INFANRIX": 3.633828503933065, "MENVEO": 2.9704376801071093, "MMRVAXPRO": 6.016484327402222, "MODERNA": 8.54038701845057, "NIMENRIX": 0.9848296994646206, "PREVENAR": 4.198938032368928, "SHINGRIX": 1.684608463366059, "SPIKEVAX": 9.183138287206155, "TOZINAMERAN": 1.1296171691227366, "TWINRIX": 1.1985350043185607, "VAXZEVRIA": 0.7452633024128598, "ZOSTAVAX": 0.4637386133189408, "null": 0.0346021496606162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12412.json
new file mode 100644
index 00000000000..276a9f52a8b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12412.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.3680778524137476, "SPIKEVAX": 3.3717636925206103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12413.json
new file mode 100644
index 00000000000..fd64a5307c7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12413.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.87537236007064, "GARDASIL": 0.4882390421692903, "HEXYON": 19.683592590916295, "MMRVAXPRO": 6.036000036173157, "MODERNA": 27.52946239533655, "NIMENRIX": 1.9935800783223592, "SHINGRIX": 2.355813867948944, "SPIKEVAX": 12.813142234509296, "TOZINAMERAN": 3.1363522064246028, "VAXZEVRIA": 1.0308665834214887, "ZOSTAVAX": 2.068294398917077, "null": 0.0550725230152568}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12414.json
new file mode 100644
index 00000000000..ec610c70adf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12414.json
@@ -0,0 +1 @@
+{"BEXSERO": 2.949434499431613, "COMIRNATY": 3.949188857063099, "ELASOMERAN": 4.423278918838049, "GARDASIL": 0.522400368709601, "INFANRIX": 4.933160307665346, "MENVEO": 4.241724472995453, "MMRVAXPRO": 4.148559475933312, "MODERNA": 12.233662358853032, "NIMENRIX": 3.737095393930247, "PREVENAR": 2.2657043746261927, "ROTATEQ": 0.8145749879444538, "SHINGRIX": 2.4642977727690805, "SPIKEVAX": 8.126575220960033, "TOZINAMERAN": 0.2896179385834083, "TWINRIX": 1.7417619151679484, "VAXZEVRIA": 2.177532215448793, "ZOSTAVAX": 0.3436392198567901, "null": 0.0854459422425411}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12415.json
new file mode 100644
index 00000000000..5a98f82ba2c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12415.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.2895739086620366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12416.json
new file mode 100644
index 00000000000..022b7f22753
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12416.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.3152195951034886, "MMRVAXPRO": 34.217966005721514, "SPIKEVAX": 1.7220819980892186, "VAXZEVRIA": 0.572022305860984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12417.json
new file mode 100644
index 00000000000..a5d2c18a27a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12417.json
@@ -0,0 +1 @@
+{"BEXSERO": 2.96654134738215, "COMIRNATY": 4.922309750134531, "FLUCELVAX": 7.627520568986903, "GARDASIL": 0.8153933800992194, "HEXYON": 7.553123867549315, "HUMIRA": 0.1295522092855175, "INFANRIX": 3.555226572751404, "MENVEO": 5.737976516164305, "MMRVAXPRO": 5.4202125544230855, "MODERNA": 2.7676956969680897, "NIMENRIX": 4.235572733716167, "PREVENAR": 2.9137835919171184, "SHINGRIX": 2.533202111257863, "SPIKEVAX": 7.08153072532756, "TOZINAMERAN": 1.743648389603747, "TWINRIX": 0.8173620764239858, "VAXZEVRIA": 1.8090945262970628, "ZOSTAVAX": 0.6145404309869898, "null": 0.0520964171538232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12418.json
new file mode 100644
index 00000000000..a9688233dcc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12418.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.173967020046134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12419.json
new file mode 100644
index 00000000000..e071d769c13
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12419.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.4815812034308427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1242.json
index 90b034456be..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1242.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1242.json
@@ -1 +1 @@
-{"BUPIVACAINE": 44.37727052545057, "BUPRENORPHINE": 7.361215404242665, "DEXAMETHASONE": 4.245773985337802, "FENTANYL": 55.22735867175306, "LEVETIRACETAM": 4.348513057783526, "MANNITOL": 120.68706507158598, "MIDAZOLAM": 12.967504067582851, "SUBOXONE": 4.459945284497608, "TRACTOCILE": 236.24926298570804, "null": 2.6375230386540083}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12420.json
new file mode 100644
index 00000000000..ea0f9ef8eb0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12420.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.182649899687352, "MMRVAXPRO": 3.3470804440743254, "MODERNA": 16.703885216285972, "SPIKEVAX": 9.844205031402227, "TOZINAMERAN": 3.8663334700940895, "VAXZEVRIA": 0.4973513989282044, "null": 0.0982636459389146}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12421.json
new file mode 100644
index 00000000000..45fd885d030
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12421.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.5713715935018375, "MMRVAXPRO": 87.9787336902428, "SPIKEVAX": 2.276433878826524, "TOZINAMERAN": 1.8813769004146927, "VAXZEVRIA": 0.6205490221628673, "ZOSTAVAX": 4.524254702569486, "null": 0.4852821203113239}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12422.json
new file mode 100644
index 00000000000..9ffde7f3a3b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12422.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.795540129451226, "FLUCELVAX": 8.153613813418167, "GARDASIL": 0.7363955196553627, "MENVEO": 15.74673184308442, "MMRVAXPRO": 1.0982034122243676, "MODERNA": 7.892420125927168, "NIMENRIX": 6.25805666134014, "SHINGRIX": 3.652312274873157, "SPIKEVAX": 8.86583638026166, "TOZINAMERAN": 2.7981923122132835, "VAXZEVRIA": 2.0699474567218545, "ZOSTAVAX": 1.059547828263421, "null": 0.087766713217393}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12423.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12423.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12424.json
new file mode 100644
index 00000000000..6027d480128
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12424.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.958806811381425, "SPIKEVAX": 14.188453718405372, "TOZINAMERAN": 1.0964043892351578, "VAXZEVRIA": 0.2048950621598144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12425.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12425.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12426.json
new file mode 100644
index 00000000000..cc920c16436
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12426.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8768183598803021, "GARDASIL": 88.77815959694844, "SPIKEVAX": 4.030741665472295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12427.json
new file mode 100644
index 00000000000..db615c21062
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12427.json
@@ -0,0 +1 @@
+{"null": 2.855567181876348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12428.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12428.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12429.json
new file mode 100644
index 00000000000..46cdfe95df3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12429.json
@@ -0,0 +1 @@
+{"null": 4.935251290477196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1243.json
index 8ed5657f4db..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1243.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1243.json
@@ -1 +1 @@
-{"KEPPRA": 6.761482244214876, "TRACTOCILE": 536.6381484931023, "null": 4.860418217932575}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12430.json
new file mode 100644
index 00000000000..3e60c4be307
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12430.json
@@ -0,0 +1 @@
+{"KEPPRA": 109.88963584333835, "null": 0.261566081877385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12431.json
new file mode 100644
index 00000000000..228e4ea5e1c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12431.json
@@ -0,0 +1 @@
+{"JARDIANCE": 32.84726066367645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12432.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12432.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12433.json
new file mode 100644
index 00000000000..f4182f3252d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12433.json
@@ -0,0 +1 @@
+{"null": 0.7722266379170711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12434.json
new file mode 100644
index 00000000000..63a755acd72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12434.json
@@ -0,0 +1 @@
+{"RITUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12435.json
new file mode 100644
index 00000000000..f391fa3036d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12435.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 1.685053847492284, "null": 0.475439175831845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12436.json
new file mode 100644
index 00000000000..314e55022cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12436.json
@@ -0,0 +1 @@
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12437.json
new file mode 100644
index 00000000000..298db180033
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12437.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 11.706274721017598, "ALIGN": 164.720966623618, "AMINOSALICYLIC": 87.03466527243312, "AVAMYS": 45.6489737456856, "BUDESONIDE": 62.11813741416628, "CHAMPIX": 0.3789779912626346, "COMIRNATY": 0.7478626436837087, "ELLAONE": 95.53899126990868, "ESMYA": 13.615477879323098, "GARDASIL": 0.6749299461795553, "ISENTRESS": 2.9949153766858427, "JARDIANCE": 0.4352930347159363, "KAFTRIO": 2.264192554346999, "MODERNA": 0.613789844932538, "OVITRELLE": 21.034741252317108, "PREGABALIN": 25.06697748644396, "SPIKEVAX": 0.3874576190127603, "SUBOXONE": 0.8314881816722686, "TOZINAMERAN": 0.5052037029187578, "VAXZEVRIA": 0.1952262394576331, "null": 0.7083010762591591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12438.json
new file mode 100644
index 00000000000..6ff041f8f2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12438.json
@@ -0,0 +1 @@
+{"null": 1.708403116740216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12439.json
new file mode 100644
index 00000000000..97026e1c554
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12439.json
@@ -0,0 +1 @@
+{"null": 1.6394521558220654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1244.json
index d11f641c944..1d54a1a6a96 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1244.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1244.json
@@ -1 +1 @@
-{"ABILIFY": 2.265202411747282, "ARIPIPRAZOLE": 4.68858286478198, "AZILECT": 41.09599081372991, "BOTULINUM": 20.57437389304109, "BRINTELLIX": 4.544980697167464, "CARBIDOPA": 41.10408680633508, "COMTAN": 24.09326408405268, "DENOSUMAB": 20.277515825425343, "ENTACAPONE": 56.495550805304994, "HUMALOG": 1.014544548506456, "KEPPRA": 1.9200789611617344, "LANTUS": 1.4576594517264492, "LEVODOPA": 35.247123554883295, "OLANZAPINE": 20.263084058876075, "RISPERIDONE": 16.140439068982165, "SPIRONOLACTONE": 10.966886660036874, "SYCREST": 44.57062450084656, "XELJANZ": 1.0841373943211428, "YESCARTA": 15.289778675334308, "ZYPREXA": 2.7018454460739987, "null": 1.869158690348889}
\ No newline at end of file
+{"ANAKINRA": 639.6686229968712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12440.json
new file mode 100644
index 00000000000..8f75614d70a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12440.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 26.045754531911037, "ALIGN": 351.0289539109318, "AMINOSALICYLIC": 206.98563694845055, "AVAMYS": 103.03481513515058, "BUDESONIDE": 168.64470450846497, "PREGABALIN": 54.24095847579364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12441.json
new file mode 100644
index 00000000000..8f55dca2288
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12441.json
@@ -0,0 +1 @@
+{"ARAVA": 32.71042623101542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12442.json
new file mode 100644
index 00000000000..d4c1a083cb5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12442.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.9969099298880922, "AIMOVIG": 0.5010358808497133, "APIDRA": 0.3008018110923102, "ARAVA": 0.0470097787837578, "ARIXTRA": 4.369567826302657, "AUBAGIO": 0.1816387216055836, "BRILIQUE": 0.7071895300229752, "BRINTELLIX": 1.4972255597441442, "BUPRENORPHINE": 0.7906195315418215, "BYDUREON": 0.276617620335555, "CHAMPIX": 0.6277964404588132, "CICLOSPORIN": 0.0954662764295119, "CIMZIA": 0.204866931766149, "CLOPIDOGREL": 0.5671873145099766, "COMIRNATY": 1.8270206091794083, "CYMBALTA": 0.390883535861753, "CYTARABINE": 0.2304450644835145, "DEXAMETHASONE": 0.6547059832124906, "DOCETAXEL": 0.5190590766677168, "ELIQUIS": 2.138883144169996, "ELLAONE": 85.60030502460712, "ENOXAPARIN": 2.631411277773489, "ESMYA": 10.216193869335347, "EVISTA": 2.551841988688668, "EVRA": 20.724463402346466, "FASLODEX": 1.021269658305784, "FENTANYL": 0.2640371025768376, "FIRDAPSE": 1.117984677913722, "FORSTEO": 0.3157764004564645, "FORXIGA": 0.5011872251924552, "GARDASIL": 0.5037124075376155, "HUMALOG": 0.2393783458626769, "HYDROCORTISONE": 0.5389997998473274, "IBRANCE": 0.2769693739106841, "IBUPROFEN": 0.2570770908994025, "JARDIANCE": 0.3794968979861531, "KEPPRA": 0.1825090526597511, "KEYTRUDA": 0.333911255177914, "LANTUS": 0.2066491899476394, "LEMTRADA": 0.4738471292718088, "LIXIANA": 4.409942861292236, "METHOTREXATE": 0.3806903964029471, "MISOPROSTOL": 25.645141802749496, "MODERNA": 1.1290058191813557, "NEXAVAR": 0.1552952180338702, "OCRELIZUMAB": 1.162743845176293, "OPSUMIT": 0.2069847273054534, "PEGASYS": 0.6077767656638748, "PEGINTRON": 0.3065967060710133, "PLAVIX": 1.4671963981402347, "RYEQO": 13.048797638803364, "SAXENDA": 0.5503138019291212, "SIMPONI": 0.1462860781705583, "SOLIRIS": 0.800778540849136, "SPIKEVAX": 1.1172325635093383, "STELARA": 0.5781658314567232, "STIVARGA": 0.393521470192186, "SUBOXONE": 1.4744436542780457, "SUTENT": 0.4516126363711814, "TAMIFLU": 0.3183357975237202, "TASIGNA": 0.3820072543845242, "TOVIAZ": 0.8530208156936087, "TOZINAMERAN": 2.96881854852545, "VAXZEVRIA": 1.261558492235216, "VOTRIENT": 0.5425643427312874, "XARELTO": 8.649417851682612, "XELJANZ": 0.1491948580478235, "XOLAIR": 0.3557718912326781, "ZYPREXA": 0.3963134390662548, "null": 1.2492919017064334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12443.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12443.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12444.json
new file mode 100644
index 00000000000..3cde21874c1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12444.json
@@ -0,0 +1 @@
+{"ARAVA": 0.6237541185536731, "COMIRNATY": 0.3087989955147836, "COSENTYX": 17.156050856163723, "FORXIGA": 38.07786338606903, "GARDASIL": 1.6031491755871112, "IRON": 24.510645159189917, "JARDIANCE": 36.94370640947636, "METHOTREXATE": 4.380079469928822, "PEGASYS": 1.2823377213217777, "SIMPONI": 3.350090473310112, "SPIKEVAX": 0.1470386193609426, "VAXZEVRIA": 0.101630872177022, "XELJANZ": 2.290629068954235, "ZOSTAVAX": 2.0807230912580734, "ZYPREXA": 1.560295200099494, "null": 1.0549863540243307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12445.json
new file mode 100644
index 00000000000..2eb8cff44eb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12445.json
@@ -0,0 +1 @@
+{"null": 0.3568059494881493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12446.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12446.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12447.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12447.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12448.json
new file mode 100644
index 00000000000..d67e0a09717
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12448.json
@@ -0,0 +1 @@
+{"null": 0.9439290762430228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12449.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12449.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1245.json
index 8d827280f4f..ac1f165de35 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1245.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1245.json
@@ -1 +1 @@
-{"ABILIFY": 2.257940766582806, "ARIPIPRAZOLE": 1.45983650133175, "BRINTELLIX": 2.543351216056098, "BUPRENORPHINE": 2.197732525837472, "CELECOXIB": 6.6292361675819365, "CHAMPIX": 2.8100834984163345, "CYMBALTA": 1.7961106399344282, "DULOXETINE": 9.696719647888068, "HUMALOG": 1.222235624232045, "KEPPRA": 3.945759816831539, "LANTUS": 1.5111955096926897, "LATUDA": 3.042817636044981, "LEVETIRACETAM": 3.5875613242267845, "LYRICA": 2.300529457551669, "OLANZAPINE": 2.3138872649264988, "PREGABALIN": 2.952202208670751, "YESCARTA": 17.15757591743116, "ZYPADHERA": 5.382589566057559, "ZYPREXA": 2.6534028205758537, "null": 2.202819665104296}
\ No newline at end of file
+{"APREPITANT": 72.22825313802474, "BYETTA": 6.360285941665228, "COMIRNATY": 0.0567349620737338, "ELIQUIS": 0.9773464333526198, "HUMALOG": 3.39688373276407, "JANUMET": 4.857867188939815, "JANUVIA": 3.899518240351196, "PLAVIX": 5.104457474926544, "ZOSTAVAX": 5.60265196099114, "null": 2.622291404172972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12450.json
new file mode 100644
index 00000000000..43ba62c416a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12450.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7497981146806301, "null": 1.992354119715068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12451.json
new file mode 100644
index 00000000000..0425ad7e9e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12451.json
@@ -0,0 +1 @@
+{"null": 1.7542884862173502}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12452.json
new file mode 100644
index 00000000000..778f4aad1f0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12452.json
@@ -0,0 +1 @@
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12453.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12453.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12454.json
new file mode 100644
index 00000000000..926a668ffac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12454.json
@@ -0,0 +1 @@
+{"null": 0.9941356751398872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12455.json
new file mode 100644
index 00000000000..687919f0f42
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12455.json
@@ -0,0 +1 @@
+{"IBUPROFEN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12456.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12456.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12457.json
new file mode 100644
index 00000000000..2cd59551b52
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12457.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": 1.9833780192780075, "null": 0.7752521796907355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12458.json
new file mode 100644
index 00000000000..84b1956e969
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12458.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.475309618467427, "null": 0.715243228416571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12459.json
new file mode 100644
index 00000000000..8b47c3733f0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12459.json
@@ -0,0 +1 @@
+{"NAGLAZYME": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1246.json
index 5b5d1385c9a..49a7dc9c18c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1246.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1246.json
@@ -1 +1 @@
-{"AZACITIDINE": 13.955491513341414, "BENZODIAZEPINE": 24.296804307395703, "BUPRENORPHINE": 10.589530073797471, "ELIQUIS": 1.1347525285291855, "FENTANYL": 2.1766872591886703, "LEVETIRACETAM": 2.3146938810641284, "LYRICA": 4.252488055549134, "MIDAZOLAM": 13.7373675721881, "NALOXONE": 70.86399642644066, "OLANZAPINE": 1.5907882064663572, "PREGABALIN": 27.22460288554129, "SUFENTANIL": 12.13644301079264, "null": 7.390258809427916}
\ No newline at end of file
+{"DESLORATADINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12460.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12460.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12461.json
new file mode 100644
index 00000000000..95332f488f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12461.json
@@ -0,0 +1 @@
+{"CUBICIN": 21.82925127112264, "CYTARABINE": 5.785532944490518, "null": 14.44319903539842}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12462.json
new file mode 100644
index 00000000000..15ea725d881
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12462.json
@@ -0,0 +1 @@
+{"BUSULFAN": 45.20995405035068, "TEMOZOLOMIDE": 133.89355413218908, "null": 0.9892125477593778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12463.json
new file mode 100644
index 00000000000..b795d2325f2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12463.json
@@ -0,0 +1 @@
+{"null": 1.4474965486280291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12464.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12464.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12465.json
new file mode 100644
index 00000000000..23f4b555674
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12465.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 2.5629311145017697, "AZATHIOPRINE": 1.032501686492542, "CELLCEPT": 3.253127776648729, "CICLOSPORIN": 0.8785510912615048, "COMIRNATY": 0.0885589977029412, "METHOTREXATE": 0.5970173432664722, "MMRVAXPRO": 0.8766859177044192, "NIMENRIX": 1.26366074164777, "RITUXIMAB": 0.7084698724519598, "ROACTEMRA": 1.2011142646765975, "SHINGRIX": 2.380233506327491, "SIMPONI": 1.0800608169820352, "SOLIRIS": 0.6745312617059654, "SPIKEVAX": 0.0778013375719175, "STELARA": 0.3248676243094635, "SYNAGIS": 2.6001533191040567, "TOZINAMERAN": 0.1129785266703749, "VAXZEVRIA": 0.0707020263027545, "XELJANZ": 0.2283658330074247, "ZOSTAVAX": 5.577685766590765, "null": 13.534324322002853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12466.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12466.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12467.json
new file mode 100644
index 00000000000..df1f855519e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12467.json
@@ -0,0 +1 @@
+{"null": 44.45453224205401}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12468.json
new file mode 100644
index 00000000000..96d01983cd5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12468.json
@@ -0,0 +1 @@
+{"null": 2.1811474582026085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12469.json
new file mode 100644
index 00000000000..ef41956a3b8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12469.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5647589928056476, "ZOSTAVAX": 57.60834562183031, "null": 0.5413030715438013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1247.json
index 65015d6bb63..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1247.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1247.json
@@ -1 +1 @@
-{"AMIKACIN": 26.55995398593603, "CELLCEPT": 9.962954724776148, "CICLOSPORIN": 16.257647498583673, "CYTARABINE": 6.997565443782843, "DEXAMETHASONE": 7.215293244777227, "LEVOFLOXACIN": 2.959564359518636, "MYCOPHENOLATE": 16.074020065500108, "PEGASYS": 2.553401724187239, "PEGINTRON": 2.833479219816101, "VORICONAZOLE": 24.318992157061302}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12470.json
new file mode 100644
index 00000000000..63a755acd72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12470.json
@@ -0,0 +1 @@
+{"RITUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12471.json
new file mode 100644
index 00000000000..2dbaa3c446b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12471.json
@@ -0,0 +1 @@
+{"CELLCEPT": 37.97330019099558, "ZOSTAVAX": 73.01766839458236, "null": 0.2977256987536396}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12472.json
new file mode 100644
index 00000000000..9ec10b68b55
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12472.json
@@ -0,0 +1 @@
+{"SHINGRIX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12473.json
new file mode 100644
index 00000000000..e4c30554d1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12473.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.6158888936311302, "ALEMTUZUMAB": 32.05755841070756, "BORTEZOMIB": 16.88964894513963, "BUSULFAN": 20.352888633884263, "CELLCEPT": 5.429395185800526, "CICLOSPORIN": 18.991353323587656, "COMIRNATY": 0.501118268513537, "CYTARABINE": 6.7404349733585445, "DEXAMETHASONE": 3.2690655975285146, "MYCOPHENOLATE": 24.95384070104273, "RINVOQ": 9.662735858293374, "RITUXIMAB": 4.054658631217095, "SHINGRIX": 10.856740810180936, "SPIKEVAX": 0.2085875232365882, "TACROLIMUS": 22.159620992696937, "THALIDOMIDE": 25.852618001457504, "TOZINAMERAN": 0.6115135806710301, "VAXZEVRIA": 0.1643550680885724, "ZOSTAVAX": 11.324886292904983, "null": 0.4696395421964717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12474.json
new file mode 100644
index 00000000000..9bc1719e2f2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12474.json
@@ -0,0 +1 @@
+{"ADCIRCA": 21.885270361976197, "ATRIPLA": 0.5003565851421077, "AVASTIN": 11.109318120336772, "CLOPIDOGREL": 2.116965838518975, "EFAVIRENZ": 13.704253364061334, "ELIQUIS": 0.948551220629302, "EMTRICITABINE": 22.74528012338434, "EPCLUSA": 27.045297843789857, "EPIVIR": 35.63120988309785, "HARVONI": 12.72467366239956, "INCIVO": 7.966398189541869, "JAKAVI": 11.492090004930157, "JANUMET": 4.941171264099967, "KALETRA": 12.151928202666555, "NEXAVAR": 6.068199854847933, "OCALIVA": 24.7514758920342, "OPSUMIT": 2.2177287176972422, "PEGASYS": 13.218864828360244, "PEGINTRON": 6.368217206785163, "RIBAVIRIN": 13.629255882454062, "null": 0.5382242675718865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12475.json
new file mode 100644
index 00000000000..0ecc1954300
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12475.json
@@ -0,0 +1 @@
+{"ABACAVIR": 16.96637215021089, "COMIRNATY": 0.3850425307836702, "null": 2.593691010865034}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12476.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12476.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12477.json
new file mode 100644
index 00000000000..05ce63c7ba3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12477.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.2215181852691925, "VAXZEVRIA": 4.156817411213976, "null": 0.1454189034531735}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12478.json
new file mode 100644
index 00000000000..1966f8e87b8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12478.json
@@ -0,0 +1 @@
+{"ENBREL": 22.2650318352459, "null": 0.3998520300511085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12479.json
new file mode 100644
index 00000000000..bb16f981e68
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12479.json
@@ -0,0 +1 @@
+{"APIDRA": 1.863261034033592, "BELIMUMAB": 90.30049662250867, "BENLYSTA": 3.792892174522168, "COMIRNATY": 1.4187909030192245, "CYMBALTA": 1.6794956499732732, "ELIQUIS": 3.8171294637781696, "EVISTA": 11.72192109213458, "FORSTEO": 2.6850119467338605, "IBRANCE": 1.0410753916028606, "INSULIN": 1.893142715537942, "JANUVIA": 1.7242838962347211, "LANTUS": 0.8669133388095422, "NUCALA": 1.2385894445279502, "OFEV": 3.4721469064555444, "PEGASYS": 0.5808274048692434, "PEGINTRON": 1.231949365128881, "SIMPONI": 3.562863147155736, "SPIKEVAX": 0.6473853508882139, "STELARA": 0.9143615730517988, "SUTENT": 0.5055426182379168, "TOZINAMERAN": 1.006508626868185, "VAXZEVRIA": 1.952183200642731, "XELJANZ": 1.38271483702583, "ZOSTAVAX": 2.3199511327266293, "null": 0.5977488059201563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1248.json
index e41ad0c4110..534b60bf7ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1248.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1248.json
@@ -1 +1 @@
-{"ELIQUIS": 10.581484980839774, "null": 1.1590848764479804}
\ No newline at end of file
+{"COMIRNATY": 1.0748234480478671, "null": 0.6236113365267257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12480.json
new file mode 100644
index 00000000000..87b490a5593
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12480.json
@@ -0,0 +1 @@
+{"null": 1.56340807827671}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12481.json
new file mode 100644
index 00000000000..3a829ba7181
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12481.json
@@ -0,0 +1 @@
+{"NEXAVAR": 64.65052143230412, "null": 0.2712220499508301}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12482.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12482.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12483.json
new file mode 100644
index 00000000000..47eecc89846
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12483.json
@@ -0,0 +1 @@
+{"ABATACEPT": 18.84427211959225, "CYTARABINE": 39.89214261637929, "NAGLAZYME": 102.4493073928636, "RUCONEST": 874.2489271379047, "null": 0.3518832759729211}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12484.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12484.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12485.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12485.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12486.json
new file mode 100644
index 00000000000..b0db2a5b3dd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12486.json
@@ -0,0 +1 @@
+{"RUCONEST": 13158.557593359932}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12487.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12487.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12488.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12488.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12489.json
new file mode 100644
index 00000000000..7709c2a7a14
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12489.json
@@ -0,0 +1 @@
+{"null": 0.5623079634166885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1249.json
index a6d0add9313..1814f475b18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1249.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1249.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 1.6018459453535523, "CYMBALTA": 1.3590700153001842, "DULOXETINE": 17.729462386943073, "EPIVIR": 15.313579017993831, "FENTANYL": 4.545313071191781, "IBUPROFEN": 5.082746119840254, "MIDAZOLAM": 13.21952862325068, "NALOXONE": 68.56268387164482, "NOVOSEVEN": 25.612816933672114, "OLANZAPINE": 3.165511673955791, "SOLIRIS": 4.301777384748771, "SPINRAZA": 11.070390026079266, "TAMIFLU": 4.459372039558303, "ZYPREXA": 2.70301258780795, "null": 1.721434405775525}
\ No newline at end of file
+{"GARDASIL": 79.02833825866827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12490.json
new file mode 100644
index 00000000000..eab1267eb1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12490.json
@@ -0,0 +1 @@
+{"RUCONEST": 4122.597864893069}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12491.json
new file mode 100644
index 00000000000..7ab72c78883
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12491.json
@@ -0,0 +1 @@
+{"PRASUGREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12492.json
new file mode 100644
index 00000000000..4c622802e4b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12492.json
@@ -0,0 +1 @@
+{"null": 1.1699170674426764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12493.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12493.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12494.json
new file mode 100644
index 00000000000..cdb087b10af
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12494.json
@@ -0,0 +1 @@
+{"KIOVIG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12495.json
new file mode 100644
index 00000000000..2c261eeb256
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12495.json
@@ -0,0 +1 @@
+{"null": 1.9007439671806237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12496.json
new file mode 100644
index 00000000000..b80e8336b81
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12496.json
@@ -0,0 +1 @@
+{"ALISKIREN": 234.6591583672312, "null": 0.9253903196272736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12497.json
new file mode 100644
index 00000000000..e3b493a114f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12497.json
@@ -0,0 +1 @@
+{"ELIQUIS": 42.23872369664178, "null": 0.7934161955149596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12498.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12498.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12499.json
new file mode 100644
index 00000000000..3ef04c811d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12499.json
@@ -0,0 +1 @@
+{"null": 0.7686757609157693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/125.json
index f3ef80d1ab9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/125.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3582217729186092, "FAMPYRA": 14.206156265711956, "GARDASIL": 22.16354484870209, "MMRVAXPRO": 4.90569215227574, "NIMENRIX": 15.707706326410412, "SHINGRIX": 4.933298989315599, "TOZINAMERAN": 1.230418072879763, "TWINRIX": 12.709154182156484, "VAXZEVRIA": 1.9812347698279655}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1250.json
index 0fbec26a7c3..c765dc0b963 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1250.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1250.json
@@ -1 +1 @@
-{"AIMOVIG": 3.2686543840351256, "AUBAGIO": 1.2759991206432126, "BENLYSTA": 2.1332784180768622, "BORTEZOMIB": 3.80838561950461, "BOSULIF": 3.43538619487984, "BRAFTOVI": 1.871113201662488, "BRINTELLIX": 1.2555008037433264, "CARFILZOMIB": 2.364148667991097, "CELECOXIB": 1.2140065027761149, "COMIRNATY": 1.8176181105333729, "COVID19": 1.7550430522677456, "CYMBALTA": 1.5918396058551665, "DULOXETINE": 1.6756032772816962, "ENTYVIO": 1.5261826657337183, "FIRDAPSE": 1.9889724147795456, "GARDASIL": 1.707249315118888, "HARVONI": 1.7183451309681066, "HIZENTRA": 1.1106018136726987, "IBRANCE": 3.014784163604771, "IRON": 2.810825917073342, "KAFTRIO": 4.232709832453297, "KESIMPTA": 2.0216948139048894, "NEULASTA": 1.2009777139717626, "PEGASYS": 1.1963797860857557, "RUBRACA": 1.5715213449794023, "SPIKEVAX": 1.514225422787706, "TEDUGLUTIDE": 23.49891729025513, "TOZINAMERAN": 6.558693573849739, "XELJANZ": 1.1010304230747587, "XYREM": 2.345878159167349}
\ No newline at end of file
+{"null": 6.102256784039449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12500.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12500.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12501.json
new file mode 100644
index 00000000000..13361aea1fc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12501.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2170646337617404, "LANTUS": 4.798553354654567, "ZYPREXA": 7.412748895653999, "null": 0.8397335019834962}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12502.json
new file mode 100644
index 00000000000..d24ccac207b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12502.json
@@ -0,0 +1 @@
+{"ADCIRCA": 40.55112942673605, "ADEMPAS": 14.688126258422871, "ADVATE": 47.4278604348247, "ALEMTUZUMAB": 8.008228457635743, "AMBRISENTAN": 34.23346945907328, "AVASTIN": 3.4677502402851026, "BEVACIZUMAB": 3.705749674219119, "BORTEZOMIB": 20.45438759252028, "CINRYZE": 155.2045432124882, "DOCETAXEL": 4.411997310390493, "ELIQUIS": 0.5601555988293678, "MACITENTAN": 70.098781817112, "METHOTREXATE": 2.1780003911561456, "OPSUMIT": 30.12073156580751, "REVESTIVE": 110.71144344430743, "RUCONEST": 48.001159839670464, "SOLIRIS": 6.547592875523947, "TRACLEER": 28.89979877487792, "null": 1.9051761415411568}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12503.json
new file mode 100644
index 00000000000..beb065fa1c2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12503.json
@@ -0,0 +1 @@
+{"null": 1.7780268225137763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12504.json
new file mode 100644
index 00000000000..5c4d9d292fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12504.json
@@ -0,0 +1 @@
+{"BEDAQUILINE": 117.62320384450376, "COMIRNATY": 0.4368764292924724, "null": 0.6597254716059914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12505.json
new file mode 100644
index 00000000000..100f0a54d16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12505.json
@@ -0,0 +1 @@
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12506.json
new file mode 100644
index 00000000000..4d7a1f05877
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12506.json
@@ -0,0 +1 @@
+{"null": 0.6780206922776975}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12507.json
new file mode 100644
index 00000000000..ae972e23c68
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12507.json
@@ -0,0 +1 @@
+{"AVANDIA": 48.133238740483016, "ELIQUIS": 1.4708320165581628, "HUMALOG": 4.523214037666957, "JANUMET": 6.452704886085053, "JARDIANCE": 11.2652316353317, "LANTUS": 16.098689385265146, "PLAVIX": 6.806901537343005, "XTANDI": 4.104576591490448, "null": 0.9343952888154702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12508.json
new file mode 100644
index 00000000000..c2194490d2c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12508.json
@@ -0,0 +1 @@
+{"null": 1.353381310351706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12509.json
new file mode 100644
index 00000000000..c7dee66e5aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12509.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6796042697371579, "TOZINAMERAN": 2.6868889792699457, "VAXZEVRIA": 6.372447584032685, "null": 0.3629941706090971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1251.json
index 03db645bc84..9226d81c178 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1251.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1251.json
@@ -1 +1 @@
-{"BRILIQUE": 11.383096145464124, "BUDESONIDE": 2.1818265966283708, "BUPIVACAINE": 11.88314795847874, "CELLCEPT": 5.0255576621374844, "CICLOSPORIN": 3.249463682412788, "CLOPIDOGREL": 10.450232712137264, "COMBIVIR": 20.24134123754979, "CYMBALTA": 2.65400827301843, "DEXAMETHASONE": 2.9301287044821622, "ELIQUIS": 4.3666983739358765, "ENOXAPARIN": 12.238376610482664, "FENTANYL": 2.627961663211538, "PLAVIX": 4.35350699944449, "SOLIRIS": 3.4196445622305407, "null": 1.078415849806782}
\ No newline at end of file
+{"ABATACEPT": 5.948055788320435, "ADALIMUMAB": 6.9183269156419005, "ANAKINRA": 3.026427551380453, "APREMILAST": 21.484128842708625, "ARANESP": 1.3963483761760174, "ARAVA": 2.1385627358960533, "AUBAGIO": 1.6774263801520983, "AZATHIOPRINE": 5.790917392033506, "BUSULFAN": 1.7739519243670794, "BYDUREON": 1.579350651369034, "BYETTA": 1.4977253390179546, "CELLCEPT": 9.771372352304793, "CIALIS": 130.69036397828594, "CICLOSPORIN": 9.903812857508848, "CIMZIA": 2.173187934419552, "COAPROVEL": 3.713184985108468, "COMIRNATY": 0.0897004960392384, "COSENTYX": 2.151731973172077, "DEXAMETHASONE": 1.7664694854628051, "ELIQUIS": 1.027806821550256, "ENBREL": 19.77686439695485, "ENTRESTO": 0.6349810910270249, "ENTYVIO": 1.705979412056159, "FORSTEO": 1.2148576252897432, "HUMALOG": 0.6364393090338597, "HUMIRA": 2.110285828629564, "IMBRUVICA": 11.618107700287352, "JAKAVI": 14.179998703937608, "JANUVIA": 0.7451413429312417, "LANTUS": 0.3384440757305883, "MEKINIST": 1.1413751702799335, "MEPOLIZUMAB": 1.9777670818812028, "METHOTREXATE": 1.18394775407634, "MYCOPHENOLATE": 3.82562973979104, "OPTIMARK": 1.521402316594742, "PEGASYS": 0.2612001218951823, "REMICADE": 3.829716901860913, "REVLIMID": 9.627657870455645, "RINVOQ": 3.4267096136339203, "RITUXIMAB": 2.7802718298538784, "ROACTEMRA": 6.236262149225132, "RUXOLITINIB": 15.14115750571396, "SIMPONI": 3.692580778016973, "SPIKEVAX": 0.0331820691021911, "STELARA": 6.798883711706655, "SUTENT": 0.3788478951920118, "TADALAFIL": 45.30284295792817, "TOZINAMERAN": 0.0909422938923269, "TREMFYA": 2.1640253690078675, "VFEND": 1.334066109705635, "VIAGRA": 2.3212879676148157, "XELJANZ": 3.391464296877209, "XOLAIR": 0.8536341749628896, "ZELBORAF": 9.46161612810584, "ZOSTAVAX": 2.8016962452777614, "null": 0.6417953950695394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12510.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12510.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12511.json
new file mode 100644
index 00000000000..021068d63e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12511.json
@@ -0,0 +1 @@
+{"ARAVA": 1.0425187454546558, "CLOPIDOGREL": 5.875032347216606, "COMIRNATY": 0.4666894289274807, "SPIKEVAX": 0.3944585248573032, "TOZINAMERAN": 0.9817982716095172, "VAXZEVRIA": 0.7189952955157765, "null": 1.1936557934709553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12512.json
new file mode 100644
index 00000000000..23809856fe3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12512.json
@@ -0,0 +1 @@
+{"null": 1.2578825212992948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12513.json
new file mode 100644
index 00000000000..1569b540ec9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12513.json
@@ -0,0 +1 @@
+{"AIMOVIG": 255.03413813025372, "BOTULINUM": 140.04202490233183, "COMIRNATY": 0.1296992902187665, "GARDASIL": 11.40501691928078, "null": 0.4332718058617448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12514.json
new file mode 100644
index 00000000000..7d09b89d93f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12514.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 111.09027411685008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12515.json
new file mode 100644
index 00000000000..6ba2bd656b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12515.json
@@ -0,0 +1 @@
+{"AVANDIA": 2.842262095458905, "COMIRNATY": 0.3978961652996277, "ELIQUIS": 2.581724122422806, "HUMALOG": 8.35413837548493, "ICLUSIG": 12.789059565982903, "LANTUS": 5.372307977126477, "PLAVIX": 17.491052587296547, "SPIKEVAX": 0.1434913176176054, "TASIGNA": 7.112238232888209, "TOPOTECAN": 44.88639736293338, "VAXZEVRIA": 0.1862319628606804, "null": 1.1777631768957613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12516.json
new file mode 100644
index 00000000000..7c7d022f9a4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12516.json
@@ -0,0 +1 @@
+{"null": 0.6982302336344438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12517.json
new file mode 100644
index 00000000000..3933fe0aabf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12517.json
@@ -0,0 +1 @@
+{"ADCETRIS": 40.88787656818098, "COMIRNATY": 2.1762261530502727, "ELIQUIS": 0.7308596966783488, "ORENCIA": 54.24031379539088, "SPIKEVAX": 1.1930024312026613, "TOZINAMERAN": 1.739323444281433, "VAXZEVRIA": 3.212018349578565, "null": 0.5924910749308645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12518.json
new file mode 100644
index 00000000000..9977cee8e6f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12518.json
@@ -0,0 +1 @@
+{"null": 0.800415278061176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12519.json
new file mode 100644
index 00000000000..f1ddb92a6d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12519.json
@@ -0,0 +1 @@
+{"APIXABAN": 5.441826841944586, "CLOPIDOGREL": 29.219718816538325, "EFIENT": 64.32503891901919, "ELIQUIS": 3.308988350052437, "PLAVIX": 20.760981496459628, "null": 1.3222016808171535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1252.json
index f72246af0c0..55c409669be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1252.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1252.json
@@ -1 +1 @@
-{"PEGASYS": 2.0026783142203635, "null": 1.8214048329262087}
\ No newline at end of file
+{"STELARA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12520.json
new file mode 100644
index 00000000000..32d9d2ddf72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12520.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 37.87324914284613, "null": 1.0136294355922952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12521.json
new file mode 100644
index 00000000000..72c8a5cfbc0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12521.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3378252990115655, "COSENTYX": 1.9729819364868248, "ELIQUIS": 3.421761598390517, "NOVONORM": 32.95197618923166, "PLAVIX": 1.8942814664732677, "VAXZEVRIA": 0.1558836307066327, "null": 3.8805528885531015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12522.json
new file mode 100644
index 00000000000..8fa695fa491
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12522.json
@@ -0,0 +1 @@
+{"RIOCIGUAT": 79946.97217693867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12523.json
new file mode 100644
index 00000000000..109ef79acb1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12523.json
@@ -0,0 +1 @@
+{"null": 0.8215158129056229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12524.json
new file mode 100644
index 00000000000..cd38323442d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12524.json
@@ -0,0 +1 @@
+{"null": 1.765260696960302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12525.json
new file mode 100644
index 00000000000..7623b8de1a9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12525.json
@@ -0,0 +1 @@
+{"null": 4.7897036450259245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12526.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12526.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12527.json
new file mode 100644
index 00000000000..062417faa42
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12527.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8330924382069522, "ELIQUIS": 3.683714716636738, "SPIKEVAX": 0.2914480108533203, "VAXZEVRIA": 0.907906411607371, "VIAGRA": 10.729412250067451, "null": 0.8887960088187125}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12528.json
new file mode 100644
index 00000000000..c6aededdefa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12528.json
@@ -0,0 +1 @@
+{"null": 0.9555410430424132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12529.json
new file mode 100644
index 00000000000..6a40dce0971
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12529.json
@@ -0,0 +1 @@
+{"TASIGNA": 38.017779355632776, "null": 0.8602433431942226}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1253.json
index 75421bebc4d..f9abc667e09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1253.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1253.json
@@ -1 +1 @@
-{"ABILIFY": 1.336989033795001, "AIMOVIG": 2.140162884801881, "AVANDIA": 3.917724158352318, "BUPRENORPHINE": 7.700207391473283, "CYMBALTA": 1.727395337080195, "DOXORUBICIN": 2.690599529770381, "DULOXETINE": 4.323075393314609, "FENTANYL": 4.670279217715022, "FESOTERODINE": 172.84067716290758, "HUMALOG": 3.595874994391312, "IBUPROFEN": 3.340828773615842, "INSULIN": 1.4333519012343532, "JARDIANCE": 1.4839959771541271, "KEPPRA": 3.660031903072309, "LANTUS": 1.9812855718103264, "LATUDA": 3.477766499593059, "LYRICA": 2.334075920073229, "MIDAZOLAM": 3.785393758160047, "NALOXONE": 28.36220972493608, "NOVOSEVEN": 6.294831099992516, "OLANZAPINE": 3.004951386655479, "PLAVIX": 1.2862066020181189, "PREGABALIN": 6.0751432003971, "PROPRANOLOL": 12.312592760274702, "RISPERIDONE": 6.020931689875798, "SPINRAZA": 8.162099182819983, "SUBOXONE": 5.360301285658602, "TAMIFLU": 1.0959725044804276, "TREMFYA": 2.195912279431759, "VIAGRA": 5.539057401403409, "ZYPREXA": 2.427785694793206, "null": 2.141691015596323}
\ No newline at end of file
+{"BRILIQUE": 17.677350055938565, "CLOPIDOGREL": 7.159533611869396, "COMIRNATY": 0.4453534362736022, "ELIQUIS": 41.57991553058196, "LIXIANA": 30.532326583342925, "NEXAVAR": 5.584904634608644, "VAXZEVRIA": 0.1937102532128821, "null": 0.2987523775842238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12530.json
new file mode 100644
index 00000000000..fa8855eac45
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12530.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 13.32293565092667, "PLAVIX": 54.42567877097595, "null": 2.5972403931249493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12531.json
new file mode 100644
index 00000000000..f4404c968db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12531.json
@@ -0,0 +1 @@
+{"BRILIQUE": 82.05221464244934, "CLOPIDOGREL": 30.115473029057103, "EFIENT": 346.81937805228574, "INSULIN": 19.338211774720406, "PLAVIX": 29.251861918176044, "null": 1.17488001610505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12532.json
new file mode 100644
index 00000000000..72a7a1349b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12532.json
@@ -0,0 +1 @@
+{"ANGIOX": 89.51621675808734, "BRILIQUE": 158.33336032632988, "CLOPIDOGREL": 49.449436238815615, "COMIRNATY": 0.0277767289907546, "EFIENT": 98.72190656238784, "ELIQUIS": 0.4176692520141735, "INTEGRILIN": 27.102178320942453, "PLAVIX": 34.4684400166996, "TICAGRELOR": 30.77366095198895, "VAXZEVRIA": 0.0685286145393993, "ZYLLT": 138.0150982923855, "null": 1.851065947224744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12533.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12533.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12534.json
new file mode 100644
index 00000000000..dd8889055da
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12534.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4032329410526233, "SPIKEVAX": 0.3403311335301565, "TAMIFLU": 18.249286522458576, "TOZINAMERAN": 1.0130432784816, "VAXZEVRIA": 0.7299418313140595, "null": 0.9677712688780084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12535.json
new file mode 100644
index 00000000000..dd8482a23e9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12535.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.1667567889398086, "AERIUS": 5.026648216200437, "ALIMTA": 1.300283014411462, "AMINOSALICYLIC": 0.7337012794282172, "ANORO": 4.829891293210546, "APIXABAN": 2.654220449459224, "APROVEL": 3.717432192140981, "ARAVA": 0.7091894854878514, "AVASTIN": 0.7337402224203581, "AZATHIOPRINE": 10.688524123863145, "BENLYSTA": 2.3096904202581925, "BEOVU": 8.92847517185919, "BETAFERON": 1.7958958618818737, "BUDESONIDE": 11.918564411257377, "CELECOXIB": 20.17738209697164, "CELLCEPT": 1.4389965075997426, "CHAMPIX": 0.3931468968620383, "CICLOSPORIN": 0.4633679755953175, "CIMZIA": 1.3458866273948231, "CLOPIDOGREL": 0.7159911165465085, "COMIRNATY": 0.685343272155258, "COSENTYX": 1.2804585888189095, "CYMBALTA": 0.3730038847018541, "DEXAMETHASONE": 1.5732612571366484, "ELIQUIS": 1.1120483309011475, "ENBREL": 0.5590428968058699, "ENTRESTO": 0.4028068724913213, "ENTYVIO": 1.7013409058293805, "ETANERCEPT": 6.032032983324261, "EXJADE": 0.4290767974828508, "FASENRA": 1.9429663554190368, "FILGRASTIM": 2.6227559250273336, "FORXIGA": 0.9954829567285862, "GARDASIL": 1.0590851602915623, "HUMALOG": 0.1812374459822546, "HUMAN": 1.828805781872618, "HUMIRA": 0.5870747418682749, "INCIVO": 1.385122808998038, "IPILIMUMAB": 2.4205366342644146, "JANUMET": 0.7159807768791063, "JARDIANCE": 0.2371102264793092, "KALETRA": 1.4754974196117283, "KEPPRA": 0.2805745905144001, "KEYTRUDA": 1.0856308463976396, "LEVOFLOXACIN": 1.2192847985400284, "MEKINIST": 0.7240448036613901, "MEPOLIZUMAB": 0.5247070661205584, "METHOTREXATE": 0.4606266894031085, "MICARDIS": 0.9039338669850252, "MMRVAXPRO": 0.627168472214173, "NEULASTA": 1.2127950121393425, "NEXAVAR": 0.9503693747498044, "NUCALA": 13.470699139592597, "OPDIVO": 0.7843258845896738, "PEGASYS": 1.6672668799380257, "PEGFILGRASTIM": 10.577852194339638, "PEGINTERFERON": 1.6991951584935112, "PEGINTRON": 2.1351152580651007, "PEMBROLIZUMAB": 2.93095414895782, "PLAVIX": 0.5797561585792426, "REMICADE": 2.9211708371701763, "RIBAVIRIN": 0.8939700017926654, "RINVOQ": 0.7110467576878939, "RITUXIMAB": 1.3126750388387636, "ROACTEMRA": 4.061397453845896, "SHINGRIX": 0.6680295132855861, "SIMPONI": 2.286873101973788, "SOLIRIS": 0.5823060498849367, "SPIKEVAX": 0.4207846551138812, "STELARA": 1.6034453206483177, "SUTENT": 0.183249358169692, "TAGRISSO": 1.3446464530095008, "TAMIFLU": 1.017726165282324, "TOCILIZUMAB": 5.832308353963918, "TOZINAMERAN": 0.725213221743718, "TREMFYA": 1.212337814615614, "TWINRIX": 2.7126668606465723, "VAXZEVRIA": 0.548784248041273, "VOTRIENT": 0.5491275234801267, "XELJANZ": 0.743251505122001, "XOLAIR": 1.7375330796083737, "ZOSTAVAX": 0.7092741646421906, "ZYPREXA": 0.2685231678839095, "null": 1.2099760468067018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12536.json
new file mode 100644
index 00000000000..4e8a7b452b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12536.json
@@ -0,0 +1 @@
+{"null": 0.4175806272323522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12537.json
new file mode 100644
index 00000000000..4f803ea2532
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12537.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1990590861326704, "null": 2.2042523556153446}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12538.json
new file mode 100644
index 00000000000..7f87e3507a3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12538.json
@@ -0,0 +1 @@
+{"null": 2.429837098764564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12539.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12539.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1254.json
index 5728a83645e..c2e769d5e9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1254.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1254.json
@@ -1 +1 @@
-{"INTUNIV": 13984.089535116078, "KEPPRA": 75.9123719669328}
\ No newline at end of file
+{"COMIRNATY": 0.5756978219167499, "null": 0.5581495086483018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12540.json
new file mode 100644
index 00000000000..12cd1787694
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12540.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3566155090800836, "VAXZEVRIA": 0.2401298648341787, "null": 3.464672446581655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12541.json
new file mode 100644
index 00000000000..aebaca9983e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12541.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.8580107506762091, "AVANDIA": 1.2730397651988326, "COMIRNATY": 1.156385676974576, "CYMBALTA": 0.9459346679302968, "OPSUMIT": 1.909437355483292, "SPIKEVAX": 0.574498952866617, "TOZINAMERAN": 0.9129230547327304, "VAXZEVRIA": 2.463619084568504, "null": 1.097727716804878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12542.json
new file mode 100644
index 00000000000..52edeb77b61
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12542.json
@@ -0,0 +1 @@
+{"null": 2.0549175767812144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12543.json
new file mode 100644
index 00000000000..dc4f8668637
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12543.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 9.3962106401663, "XALKORI": 64.93326519523193, "null": 0.3321383051882046}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12544.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12544.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12545.json
new file mode 100644
index 00000000000..68af88dd43f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12545.json
@@ -0,0 +1 @@
+{"METHOTREXATE": 78.13081328255721, "null": 0.4786410390723225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12546.json
new file mode 100644
index 00000000000..a17fab68c8b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12546.json
@@ -0,0 +1 @@
+{"ENTRESTO": 8.429467771479342, "FENTANYL": 5.806899219551891, "GLUCAGON": 430.11637551698135, "null": 3.1956268132294103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12547.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12547.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12548.json
new file mode 100644
index 00000000000..edb683cc306
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12548.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2346345984491679, "DASATINIB": 73.74022813608545, "VAXZEVRIA": 0.4189736942353328, "null": 2.9192192768760528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12549.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12549.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1255.json
index d160aedb84c..a882e32955a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1255.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1255.json
@@ -1 +1 @@
-{"KEPPRA": 12.299209478137312, "null": 1.8139685924173683}
\ No newline at end of file
+{"CANNABIDIOL": 1279.3293503412715, "COMIRNATY": 0.5205497425984658}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12550.json
new file mode 100644
index 00000000000..63a755acd72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12550.json
@@ -0,0 +1 @@
+{"RITUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12551.json
new file mode 100644
index 00000000000..543f5a11606
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12551.json
@@ -0,0 +1 @@
+{"FENTANYL": 19.313077185700703, "null": 0.7411877241468018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12552.json
new file mode 100644
index 00000000000..0899e699c81
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12552.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5487380452822216, "TOZINAMERAN": 1.3439503538395128, "VAXZEVRIA": 0.9680849271542628, "null": 1.6648728583397523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12553.json
new file mode 100644
index 00000000000..9d671468e07
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12553.json
@@ -0,0 +1 @@
+{"BELIMUMAB": 142.91539099639402, "BENLYSTA": 6.861985047229591, "COMIRNATY": 0.6502522279772803, "ELIQUIS": 2.5942947706183688, "ENBREL": 6.688514713383858, "ENTRESTO": 2.562815872808366, "EXFORGE": 4.123850184264754, "FORSTEO": 2.094989132521753, "HUMALOG": 2.242319400603672, "IBRANCE": 2.638577001556369, "ILARIS": 307.9689277842574, "LANTUS": 1.466658410819533, "SPIKEVAX": 0.322380621310507, "SUTENT": 0.7959136502517343, "TOZINAMERAN": 1.798405289513385, "VAXZEVRIA": 0.6494361289672241, "VIAGRA": 7.525102830157734, "XELJANZ": 1.522787276886848, "null": 1.029107015863761}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12554.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12554.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12555.json
new file mode 100644
index 00000000000..40f03efea2e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12555.json
@@ -0,0 +1 @@
+{"BENLYSTA": 12.766272162204825, "COMIRNATY": 0.6560177697095102, "ELIQUIS": 4.852398717600861, "IBRANCE": 8.87763199863247, "RUCONEST": 80.15516947555281, "TOZINAMERAN": 0.7840741450930452, "VAXZEVRIA": 1.0603503046407436, "XELJANZ": 3.3545292094536623, "null": 0.5160355390310662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12556.json
new file mode 100644
index 00000000000..36ce4e47aab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12556.json
@@ -0,0 +1 @@
+{"null": 4.1447512675523255}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12557.json
new file mode 100644
index 00000000000..e0b7b72a73b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12557.json
@@ -0,0 +1 @@
+{"null": 0.4335501018639234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12558.json
new file mode 100644
index 00000000000..0f100ee12b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12558.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 20.99565615678052, "null": 0.5198820705880052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12559.json
new file mode 100644
index 00000000000..978a8eaa610
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12559.json
@@ -0,0 +1 @@
+{"null": 0.9004185235913372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1256.json
index 01392355590..a96a50dd56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1256.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1256.json
@@ -1 +1 @@
-{"ENTRESTO": 31.065263152780187, "IRBESARTAN": 169.5080842160149}
\ No newline at end of file
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12560.json
new file mode 100644
index 00000000000..eed8eac4b2c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12560.json
@@ -0,0 +1 @@
+{"AVASTIN": 13.805590137880264, "COMIRNATY": 0.2581299413364901, "ELIQUIS": 2.5263040966497656, "NOVOSEVEN": 169.02767191097865, "SPIKEVAX": 0.2347263020991492, "STELARA": 2.783783765682061, "SUTENT": 6.374150088928209, "VAXZEVRIA": 0.620217174828023, "VOTRIENT": 8.453369409875581, "null": 0.6520370281831486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12561.json
new file mode 100644
index 00000000000..40bf7fa990e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12561.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 63.0841236046378, "ASPARAGINASE": 11.276923933617104, "BUSILVEX": 754.830182378999, "BUSULFAN": 300.03751762238073, "CICLOSPORIN": 10.348914914976222, "CYTARABINE": 12.064854536810708, "DEFITELIO": 456.3790143771198, "EXJADE": 3.823129080982479, "METHOTREXATE": 3.671900438072597, "ONCASPAR": 28.06381476138436, "null": 0.5644741979352509}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12562.json
new file mode 100644
index 00000000000..1ad5b29ff66
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12562.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 27.01128834419746, "ASPARAGINASE": 59.22517512303188, "AVASTIN": 2.754297485724328, "AZACITIDINE": 14.185020840545617, "BESPONSA": 845.8717975460762, "BEVACIZUMAB": 3.3343970286980387, "BLINATUMOMAB": 33.65915950516605, "BUSILVEX": 271.66230054057127, "BUSULFAN": 299.8323982957023, "CAPECITABINE": 8.227285053109131, "CARMUSTINE": 58.05605697475786, "CELLCEPT": 2.833404066768685, "CICLOSPORIN": 5.518403766586602, "CYTARABINE": 19.927056216908294, "DEFITELIO": 648.445316678196, "DOXORUBICIN": 6.068349769367971, "FILGRASTIM": 7.766363574614862, "ICLUSIG": 6.92449043178623, "MELPHALAN": 92.23983851412775, "METHOTREXATE": 6.540290630002817, "MYCOPHENOLATE": 6.544657757662441, "PANITUMUMAB": 27.736317591500065, "THIOTEPA": 49.76301641465533, "null": 0.8305931856853075}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12563.json
new file mode 100644
index 00000000000..c12d274b236
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12563.json
@@ -0,0 +1 @@
+{"null": 1.308269228709178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12564.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12564.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12565.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12565.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12566.json
new file mode 100644
index 00000000000..ba2cfd39f5e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12566.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2923023094204713, "ELIQUIS": 7.086261795185171, "VAXZEVRIA": 1.0442292790144188, "null": 0.844383576170849}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12567.json
new file mode 100644
index 00000000000..6c1d792e2cd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12567.json
@@ -0,0 +1 @@
+{"null": 1.0296663492758484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12568.json
new file mode 100644
index 00000000000..617b8a270df
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12568.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 2.719890838524212, "COMIRNATY": 0.5785595244322667, "HUMALOG": 2.2699410441649097, "LANTUS": 2.7411253676274194, "SPIKEVAX": 0.247579497008612, "VAXZEVRIA": 0.4899666149473238, "null": 1.886219611060044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12569.json
new file mode 100644
index 00000000000..8309518f405
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12569.json
@@ -0,0 +1 @@
+{"null": 0.9603570280305574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1257.json
index 2410bb49669..dc30e6e55d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1257.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1257.json
@@ -1 +1 @@
-{"null": 1.2687455096402631}
\ No newline at end of file
+{"null": 2.091826519080321}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12570.json
new file mode 100644
index 00000000000..5bd9c12afb2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12570.json
@@ -0,0 +1 @@
+{"VELTASSA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12571.json
new file mode 100644
index 00000000000..cde221e5fea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12571.json
@@ -0,0 +1 @@
+{"null": 1.4408106887861092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12572.json
new file mode 100644
index 00000000000..3a593c988b8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12572.json
@@ -0,0 +1 @@
+{"ENTRESTO": 162.2718563149147}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12573.json
new file mode 100644
index 00000000000..81bb8c70b60
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12573.json
@@ -0,0 +1 @@
+{"ENTRESTO": 35.229315701683525, "IVABRADINE": 909.621439087268, "null": 0.8977937983663031}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12574.json
new file mode 100644
index 00000000000..7c0a93f1006
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12574.json
@@ -0,0 +1 @@
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12575.json
new file mode 100644
index 00000000000..4d677817413
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12575.json
@@ -0,0 +1 @@
+{"null": 0.9766116568776682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12576.json
new file mode 100644
index 00000000000..438332c02c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12576.json
@@ -0,0 +1 @@
+{"ARANESP": 1.6497167142723244, "ASPARAGINASE": 17.490025553375926, "AVASTIN": 10.207961573406449, "CICLOSPORIN": 0.8624454708575988, "CLOPIDOGREL": 0.760355721462623, "COMIRNATY": 1.4135371462668374, "CYTARABINE": 5.628463872028836, "DEXAMETHASONE": 0.8660180399998392, "ELIQUIS": 2.6531933474741813, "ENOXAPARIN": 6.833692388099344, "EVISTA": 13.76774051244228, "FORSTEO": 0.803632068756716, "KEYTRUDA": 0.464797501330508, "METHOTREXATE": 1.9156627170848408, "NOVOSEVEN": 28.67044132554181, "NPLATE": 3.3918256674430105, "REGORAFENIB": 30.666122971379, "RINVOQ": 2.984455620275952, "SPIKEVAX": 0.6457291951156858, "STELARA": 1.0074365914992758, "SUTENT": 0.7148844916320085, "TOZINAMERAN": 0.271756268849952, "VAXZEVRIA": 1.8473316850311676, "XELJANZ": 0.4975834620163875, "ZYPREXA": 0.7493759465700888, "null": 0.775402460624537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12577.json
new file mode 100644
index 00000000000..03d30d95c10
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12577.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 3.6051049870984873, "AVASTIN": 6.475433388889466, "COMIRNATY": 3.100909232320553, "ELIQUIS": 1.1278832947704085, "EVISTA": 10.71753438044166, "KEYTRUDA": 0.6599867245901508, "MODERNA": 1.5181319481193625, "NOVOSEVEN": 26.47923832804478, "RINVOQ": 7.449497138615168, "SPIKEVAX": 1.0595813123426436, "STELARA": 0.7002336077691635, "SUTENT": 0.4907404807837894, "THALIDOMIDE": 11.007824549815108, "TOZINAMERAN": 0.1147970726473566, "VAXZEVRIA": 1.7822051394828635, "XELJANZ": 0.5573885314896897, "ZYPREXA": 1.5862232038316673, "null": 0.3863204713175797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12578.json
new file mode 100644
index 00000000000..365efffc708
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12578.json
@@ -0,0 +1 @@
+{"FENTANYL": 28.321384502964964, "OPSUMIT": 80.45945793203063, "SILDENAFIL": 140.62512651391532, "null": 0.2939682002754817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12579.json
new file mode 100644
index 00000000000..f98727b5f2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12579.json
@@ -0,0 +1 @@
+{"null": 0.6150315419721749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1258.json
index 697d3697470..109ef79acb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1258.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1258.json
@@ -1 +1 @@
-{"ADCIRCA": 35.71120497221266, "ADEMPAS": 18.55263830961768, "AMBRISENTAN": 25.95471323723197, "CHOLESTAGEL": 273.17683769580447, "CICLOSPORIN": 1.0969779578883037, "CLOPIDOGREL": 1.1585215459019318, "ENTRESTO": 22.80125123847497, "EXJADE": 2.286815481654695, "JANUVIA": 3.127585634251673, "JARDIANCE": 1.2639184089782602, "KEYTRUDA": 2.249382105954308, "KYPROLIS": 23.84739247449997, "LANTUS": 1.3166983196071351, "MULTAQ": 17.529504878493565, "OPSUMIT": 18.82167604106816, "RASILEZ": 10.385910757321168, "RIVAROXABAN": 33.519517355124016, "TASIGNA": 3.123549213064432, "TRACLEER": 7.935174741042364, "null": 1.162663721101912}
\ No newline at end of file
+{"null": 0.8215158129056229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12580.json
new file mode 100644
index 00000000000..997d907c893
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12580.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.1231097998404977, "APIXABAN": 4.162451003558801, "AVANDIA": 4.790327141951398, "BENZODIAZEPINES": 105.43338101016818, "BUPIVACAINE": 12.484878862383413, "CICLOSPORIN": 1.0787019690192996, "CLOPIDOGREL": 1.5544253436031872, "COMIRNATY": 0.1985949843183972, "DEXAMETHASONE": 1.6095321363132162, "ENTRESTO": 4.719421345014501, "FENTANYL": 2.0309089728746605, "IVABRADINE": 45.93901715551617, "OLANZAPINE": 4.674510244012757, "SPIKEVAX": 0.0862361954554531, "TOZINAMERAN": 0.2132528826863683, "VAXZEVRIA": 0.0714904907300307, "null": 3.088826875164941}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12581.json
new file mode 100644
index 00000000000..5494f560411
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12581.json
@@ -0,0 +1 @@
+{"BRILIQUE": 115.3228604639432, "JARDIANCE": 16.604122537259524, "TICAGRELOR": 129.26035004649873, "null": 2.251473684684824}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12582.json
new file mode 100644
index 00000000000..fd0151db097
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12582.json
@@ -0,0 +1 @@
+{"PEMBROLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12583.json
new file mode 100644
index 00000000000..4aa5229cade
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12583.json
@@ -0,0 +1 @@
+{"ELIQUIS": 50.93226318018591, "null": 0.5421702344923595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12584.json
new file mode 100644
index 00000000000..37f1ac0fd8e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12584.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1853783086501783, "IVABRADINE": 749.0346955618561, "SUTENT": 1.2456016565905617, "VOTRIENT": 5.371430465570555, "null": 1.1962954995831867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12585.json
new file mode 100644
index 00000000000..09f6ad58920
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12585.json
@@ -0,0 +1 @@
+{"null": 1.3283080620789878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12586.json
new file mode 100644
index 00000000000..9b685cf4542
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12586.json
@@ -0,0 +1 @@
+{"null": 1.9094105922474416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12587.json
new file mode 100644
index 00000000000..2921fd9c238
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12587.json
@@ -0,0 +1 @@
+{"null": 1.5020602219664978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12588.json
new file mode 100644
index 00000000000..9ae5689dbf1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12588.json
@@ -0,0 +1 @@
+{"AIMOVIG": 0.6874957213839419, "AMINOSALICYLIC": 5.159829738245159, "AVANDIA": 1.3356028089647585, "BEDAQUILINE": 7.571458519861368, "BRIDION": 3.838730214245019, "BRILIQUE": 2.073803776672144, "BUPIVACAINE": 2.4640794259256564, "CHAMPIX": 0.858706627808574, "COMBIVIR": 1.826415606932068, "COMIRNATY": 0.9220585853698556, "CYMBALTA": 0.6433397333675754, "DAPAGLIFLOZIN": 6.707882515398371, "EDOXABAN": 34.31725144858339, "ELIQUIS": 0.3642086187547084, "EMPAGLIFLOZIN": 4.039213431661975, "ENTRESTO": 5.12228443675819, "EXFORGE": 2.04097172482194, "FENTANYL": 4.134139702726672, "FIRDAPSE": 3.630375204402277, "FORSTEO": 0.8002666080872911, "GARDASIL": 0.4301488606446625, "HUMALOG": 0.2467523943862655, "IVABRADINE": 17.103482821467775, "JANUMET": 0.6322387978610684, "KALETRA": 1.157095136415452, "KEPPRA": 0.4963716819012991, "KEYTRUDA": 0.2537642802089815, "LEVOFLOXACIN": 0.7436788919070549, "MEPOLIZUMAB": 0.8089566771764438, "MICARDIS": 1.897877849607286, "MIDAZOLAM": 4.772265392530856, "MODERNA": 0.5154775187521521, "MULTAQ": 8.343785143255133, "OLANZAPINE": 1.1331672979749066, "PEGASYS": 0.5187562378117145, "PEGINTRON": 0.6081507099240905, "PLAVIX": 0.331478154023534, "SAXENDA": 1.6134009510281822, "SIMPONI": 0.583853076252893, "SPIKEVAX": 0.6929931923436065, "SPIRONOLACTONE": 3.74426204197182, "STELARA": 0.3412854069333612, "SUFENTANIL": 4.634709394888435, "TAMIFLU": 0.8238999812304528, "TASIGNA": 2.0341742257925133, "TOZINAMERAN": 0.984397004669612, "TRISENOX": 15.59342619253204, "VAXZEVRIA": 0.1699233619734815, "VFEND": 4.020654006826653, "VIAGRA": 1.6617602649476664, "VORICONAZOLE": 2.5093890697269887, "ZOSTAVAX": 0.523343437386074, "ZYPREXA": 1.7702159827798785, "null": 1.9402956146990609}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12589.json
new file mode 100644
index 00000000000..b16ad263a03
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12589.json
@@ -0,0 +1 @@
+{"null": 1.466561082907462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1259.json
index 01e2e7c803b..54d08cb4b64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1259.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1259.json
@@ -1 +1 @@
-{"AFINITOR": 4.15923941283406, "AIMOVIG": 1.6329066143852542, "AUBAGIO": 1.6276066797197395, "BRAFTOVI": 7.443312610076406, "CELLCEPT": 1.6651868282768516, "ELIQUIS": 1.768886749249416, "ESBRIET": 2.0762734982602757, "EXFORGE": 2.382019310003202, "FAMPYRA": 3.674237714579912, "FORSTEO": 1.7427136560887455, "HUMALOG": 3.75165265767888, "IRESSA": 4.505140404453085, "JANUMET": 1.375257358766661, "KEPPRA": 10.139283232516377, "KEYTRUDA": 1.173375312949372, "LANTUS": 2.466813891399945, "MEKINIST": 11.375793718285378, "SOMATROPIN": 32.95469153570535, "STELARA": 1.4665382424228637, "SUBOXONE": 1.2254852335934818, "TAGRISSO": 6.644883522038496, "TRELEGY": 3.2777683757849188, "TRULICITY": 2.265434111126974, "VIMPAT": 10.307494621460648, "VOTRIENT": 6.669036259736003, "XELJANZ": 1.027725014765608, "XOLAIR": 1.902238067866885, "XTANDI": 1.78922011029047, "ZELBORAF": 10.077720484121896, "null": 1.578383582416234}
\ No newline at end of file
+{"null": 2.502614648328913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12590.json
new file mode 100644
index 00000000000..32dfedec681
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12590.json
@@ -0,0 +1 @@
+{"ANGIOX": 28.014567990503814, "ARANESP": 8.991325919350492, "AVANDAMET": 4.765279158410529, "AVANDIA": 6.730305156216914, "AVASTIN": 0.8746306708610013, "BRIDION": 16.162603349849242, "BRILIQUE": 1.5351395276122366, "CELLCEPT": 0.6684396607228039, "CHAMPIX": 1.089713848294307, "CLOPIDOGREL": 1.7089539968304217, "COMIRNATY": 0.2602985607164852, "CYMBALTA": 0.3983087830813256, "DARBEPOETIN": 42.8886923875399, "DEXAMETHASONE": 1.2405010985862297, "ELIQUIS": 0.6627434918622177, "ENTRESTO": 3.982400600795079, "EXFORGE": 0.8465633045619486, "FENTANYL": 5.763451839835046, "FLUTICASONE": 62.33626339741704, "FORXIGA": 0.9903149057377574, "IRBESARTAN": 5.353085921616906, "IVABRADINE": 13.381774976491432, "JARDIANCE": 0.320042080311622, "KEPPRA": 0.7499025818318069, "KEYTRUDA": 0.3577552270688292, "LEVETIRACETAM": 1.2161122766103163, "LEVOFLOXACIN": 1.8757608442788627, "MEXILETINE": 43.55973498245247, "MIDAZOLAM": 5.541536639818625, "MULTAQ": 7.301459660059155, "NORVIR": 2.601898624979444, "NOXAFIL": 3.404301669823714, "OLANZAPINE": 1.4485239599664343, "PEGINTRON": 0.4097845490987041, "PLAVIX": 1.1215109568446495, "PROPRANOLOL": 5.519725372420459, "RANOLAZINE": 8.780738603230352, "RASBURICASE": 29.93153726263183, "RITUXIMAB": 0.9145857637012856, "SILDENAFIL": 1.8456940996625384, "SPIKEVAX": 0.3219590883882962, "STELARA": 0.406869401669572, "TAGRISSO": 1.4325759996725782, "TAMIFLU": 0.7213284313722512, "TOZINAMERAN": 0.1296111729528281, "TRACLEER": 1.1290290106611507, "VAXZEVRIA": 0.0460409036371476, "VFEND": 3.5179796227732254, "VIAGRA": 3.739327185404726, "VIMPAT": 2.128275978840651, "ZYPREXA": 1.149124021287649, "null": 3.109960905984744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12591.json
new file mode 100644
index 00000000000..98be2c69087
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12591.json
@@ -0,0 +1 @@
+{"null": 3.9109356712706345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12592.json
new file mode 100644
index 00000000000..1d5ac055200
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12592.json
@@ -0,0 +1 @@
+{"ENTRESTO": 86.58848158698123, "null": 1.92648097981972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12593.json
new file mode 100644
index 00000000000..10db0282e9a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12593.json
@@ -0,0 +1 @@
+{"AVANDIA": 4.085527961301992, "AVASTIN": 8.904355929974143, "COMIRNATY": 0.1139550079219021, "ISENTRESS": 25.386123922697656, "PANTOPRAZOLE": 38.83963982959771, "null": 2.144692213636632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12594.json
new file mode 100644
index 00000000000..dc45eb22d52
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12594.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 94.36227366591687, "ARAVA": 0.2444548436107237, "ARIPIPRAZOLE": 3.841936902289118, "CICLOSPORIN": 1.046849464503021, "CLOPIDOGREL": 5.794363938523667, "COMIRNATY": 0.2585700431409459, "DAPAGLIFLOZIN": 38.78542489575379, "ENTRESTO": 5.468852504959744, "FENTANYL": 7.546323925310295, "ICLUSIG": 6.815515388489292, "IRBESARTAN": 9.683128779864218, "MEKINIST": 4.579080932440624, "METHOTREXATE": 2.6036927969278136, "OLANZAPINE": 1.4147453596739272, "PANTOPRAZOLE": 18.00943187719358, "SPIKEVAX": 0.4883523323492295, "SUTENT": 0.6494075755153168, "VALSARTAN": 24.023510920868613, "null": 1.4663013449051512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12595.json
new file mode 100644
index 00000000000..3757760a064
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12595.json
@@ -0,0 +1 @@
+{"CYMBALTA": 12.47696115252158, "null": 2.412185102749764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12596.json
new file mode 100644
index 00000000000..14a1eea5473
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12596.json
@@ -0,0 +1 @@
+{"null": 0.5421702344923595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12597.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12597.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12598.json
new file mode 100644
index 00000000000..159f7824a47
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12598.json
@@ -0,0 +1 @@
+{"ALISKIREN": 7.086557109082546, "ATRIPLA": 0.42500051269909, "COMBIVIR": 5.457577702051131, "COMIRNATY": 0.0382653316117684, "CYMBALTA": 0.4544775293703861, "EMTRICITABINE": 30.86111790984014, "HUMALOG": 1.3356347499938932, "IBUPROFEN": 4.271314026917337, "ISENTRESS": 18.7271366454741, "KALETRA": 5.8717603809967365, "KEPPRA": 3.4770304811120254, "LEVEMIR": 4.343798979905995, "LEVETIRACETAM": 6.312468236404844, "NORVIR": 16.849989176550306, "null": 5.980100291182139}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12599.json
new file mode 100644
index 00000000000..eda1846e983
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12599.json
@@ -0,0 +1 @@
+{"null": 2.039725518430392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/126.json
index b5c1f2b5459..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/126.json
@@ -1 +1 @@
-{"null": 1.5160708865908477}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1260.json
index 227e599bcb3..c4320bb9836 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1260.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1260.json
@@ -1 +1 @@
-{"HUMALOG": 13.16984413643266, "null": 1.364414289672629}
\ No newline at end of file
+{"ACE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12600.json
new file mode 100644
index 00000000000..bd38f3c5933
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12600.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.5956717761627989, "ALISKIREN": 3.893809904299432, "AMIODARONE": 52.8856459910641, "APIXABAN": 2.662107977242554, "ATAZANAVIR": 1.1883180993113756, "AVANDAMET": 7.567434640734304, "AVANDIA": 7.049131529894732, "BRIDION": 7.083296624189004, "BRILIQUE": 1.4046396008580302, "BUMETANIDE": 7.952151309760993, "BUPIVACAINE": 3.8902757405657904, "BUSULFAN": 0.8500550370679503, "CHAMPIX": 0.3083434041152136, "CICLOSPORIN": 0.2227131567806397, "CLOPIDOGREL": 2.5515029347286253, "COMIRNATY": 0.1591169476959313, "CUBICIN": 1.2524762921120547, "CYMBALTA": 0.2044515319034426, "DAPAGLIFLOZIN": 6.499412033124952, "DASATINIB": 5.100527383854425, "DEXAMETHASONE": 1.252925546108178, "DULOXETINE": 0.905982155158496, "EDOXABAN": 26.246811911367228, "ELIQUIS": 0.8168856187220169, "ENOXAPARIN": 1.109592840103497, "ENTRESTO": 8.380094961380163, "EPIVIR": 2.4952011923170843, "FENTANYL": 6.068104538750523, "GARDASIL": 0.1678300699464046, "GLUCAGON": 9.349221107426205, "HARVONI": 1.2265985657485143, "HUMALOG": 0.2826654064323434, "IBUPROFEN": 0.586766622584542, "JANUMET": 0.5033186198666487, "JARDIANCE": 1.0778754433967357, "KEPPRA": 0.4106224475769944, "KEYTRUDA": 0.5285711212337161, "LACOSAMIDE": 4.637612025704618, "LEVETIRACETAM": 1.0432762529754602, "LEVOFLOXACIN": 2.694809135382009, "MEXILETINE": 61.56323827028558, "MICARDIS": 1.4098543766912124, "MIDAZOLAM": 3.272358133717429, "MULTAQ": 15.582914583588828, "NOT": 2.27077666268135, "NOXAFIL": 2.1577874157700605, "OLANZAPINE": 1.8354930315873288, "OPSUMIT": 0.591470002407155, "PANTOPRAZOLE": 1.6347247507464384, "PEGASYS": 0.1386526022518238, "PLAVIX": 0.606296687740252, "POSACONAZOLE": 5.101424818547481, "PROPRANOLOL": 3.2548440525605367, "RANEXA": 6.273515621681442, "RANOLAZINE": 12.108423842729298, "REBETOL": 2.512822708227409, "REYATAZ": 3.6456469519206514, "SILDENAFIL": 3.768977490333261, "SPIKEVAX": 0.2317922653045613, "SPIRONOLACTONE": 5.602339938636116, "SUFENTANIL": 2.9120515816660024, "SUTENT": 0.1938832044148077, "TAGRISSO": 1.6553833398969355, "TAMIFLU": 1.3191533768312915, "TASIGNA": 0.6351140998780479, "TOZINAMERAN": 0.2046365385278411, "TRACLEER": 1.2642594133818192, "TRISENOX": 19.27148991246068, "VALSARTAN": 5.62074393667376, "VAXZEVRIA": 0.0554013746644565, "VFEND": 2.8414237504908613, "VIAGRA": 1.5256788396939855, "VILDAGLIPTIN": 26.00611653007701, "VIMPAT": 1.390285922252924, "VORICONAZOLE": 1.74661841114549, "ZOSTAVAX": 0.2132593579216013, "ZYPREXA": 1.0780170688163628, "null": 3.2949792886232707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12601.json
new file mode 100644
index 00000000000..ea8618f1c46
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12601.json
@@ -0,0 +1 @@
+{"null": 0.8652203883472588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12602.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12602.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12603.json
new file mode 100644
index 00000000000..7dfde642436
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12603.json
@@ -0,0 +1 @@
+{"CHAMPIX": 20.19304384989637, "null": 1.8879797917072807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12604.json
new file mode 100644
index 00000000000..5e92ba3428a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12604.json
@@ -0,0 +1 @@
+{"null": 0.9978144146412992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12605.json
new file mode 100644
index 00000000000..a818de5cd33
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12605.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.6331853142995003, "null": 0.3221299234189435}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12606.json
new file mode 100644
index 00000000000..0b8245b4788
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12606.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4835129563572765, "null": 0.592675607504592}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12607.json
new file mode 100644
index 00000000000..6fd37d44f43
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12607.json
@@ -0,0 +1 @@
+{"TASIGNA": 93.86954471789367, "null": 0.3096098963220699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12608.json
new file mode 100644
index 00000000000..65ccb5b512a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12608.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.0098470199883007, "VAXZEVRIA": 2.197257224530865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12609.json
new file mode 100644
index 00000000000..5327782070a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12609.json
@@ -0,0 +1 @@
+{"null": 0.8643050682675437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1261.json
index e04b10e47d1..ccb20814a20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1261.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1261.json
@@ -1 +1 @@
-{"ELIQUIS": 2.7893527163695637, "KEPPRA": 2.1869702671416995, "LANTUS": 2.474876572236433, "MEKINIST": 10.109197679668249, "TRELEGY": 13.736320069766396, "VOTRIENT": 3.735062733615496, "null": 3.425980426871486}
\ No newline at end of file
+{"null": 1.0088296720616217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12610.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12610.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12611.json
new file mode 100644
index 00000000000..4a4b99305f8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12611.json
@@ -0,0 +1 @@
+{"ATRIPLA": 14.77106299685714, "SPIKEVAX": 0.451748257051924, "STRIBILD": 22.88510668025476, "TRUVADA": 6.783656917901483, "ZOSTAVAX": 12.82053292815486, "null": 0.5610091304413465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12612.json
new file mode 100644
index 00000000000..030162d527d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12612.json
@@ -0,0 +1 @@
+{"null": 1.154427561794858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12613.json
new file mode 100644
index 00000000000..300e9b0aa95
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12613.json
@@ -0,0 +1 @@
+{"ATRIPLA": 4.343305333793597, "COMIRNATY": 0.3621671211505262, "null": 0.5020245583541936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12614.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12614.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12615.json
new file mode 100644
index 00000000000..a003d0e8988
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12615.json
@@ -0,0 +1 @@
+{"null": 0.942430388920528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12616.json
new file mode 100644
index 00000000000..ea01ad4395f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12616.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.203695591089879, "VAXZEVRIA": 1.850979419409157}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12617.json
new file mode 100644
index 00000000000..7c69b855370
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12617.json
@@ -0,0 +1 @@
+{"FORSTEO": 190.75191381203325, "null": 0.6658215277799707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12618.json
new file mode 100644
index 00000000000..23a277a6642
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12618.json
@@ -0,0 +1 @@
+{"null": 1.1086022370650432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12619.json
new file mode 100644
index 00000000000..bd00e3b521a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12619.json
@@ -0,0 +1 @@
+{"null": 1.5494092413988425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1262.json
index 37b7319395e..1aeb6c6b0ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1262.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1262.json
@@ -1 +1 @@
-{"ASPARAGINASE": 2.65165890841649, "AVASTIN": 3.706183331683051, "BEDAQUILINE": 7.484980463666909, "BENZODIAZEPINE": 11.160649193841117, "BORTEZOMIB": 5.656948749195101, "BRAFTOVI": 3.029499074691308, "BUPRENORPHINE": 6.383212401596551, "CAELYX": 2.2878285002293035, "CAPECITABINE": 1.526532156882232, "CELLCEPT": 1.5093585282454989, "CICLOSPORIN": 5.224849309408813, "CLOPIDOGREL": 1.7139259261472002, "CYTARABINE": 1.8699194645293984, "DEXAMETHASONE": 5.059762258463214, "DOXORUBICIN": 4.177056157644085, "ENOXAPARIN": 1.8127923764698928, "FENTANYL": 2.3208668665919894, "FILGRASTIM": 3.664707415618436, "IBUPROFEN": 3.64743729290516, "INLYTA": 3.067305344091216, "IRESSA": 2.976459914054294, "KEPPRA": 2.955277752189278, "KEYTRUDA": 2.316992445120237, "KYMRIAH": 3.950546775118291, "LEVETIRACETAM": 1.5183280719892644, "MANNITOL": 20.95745080810684, "MEKINIST": 2.949462287465767, "MIDAZOLAM": 6.965477575144787, "NAGLAZYME": 2.815338211238017, "NALOXONE": 27.452836616213578, "NOXAFIL": 3.990498097432586, "OLANZAPINE": 2.376411346632072, "OPDIVO": 2.2233192991500506, "PEGINTERFERON": 1.1195788360684629, "SOLIRIS": 2.6145675610783314, "TAGRISSO": 3.1302435548088, "TEMODAL": 14.23319789792493, "TEMOZOLOMIDE": 9.21045529819666, "VFEND": 1.1567437198968027, "VOTRIENT": 1.9983747828401208, "YESCARTA": 8.70466275827124, "ZYPREXA": 1.5546621140018415, "null": 1.845499150922534}
\ No newline at end of file
+{"ARIPIPRAZOLE": 87.22480467605527, "COMIRNATY": 0.5961436454144502, "null": 0.4323058731990355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12620.json
new file mode 100644
index 00000000000..02379b905a4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12620.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.1063872512176792, "ABASAGLAR": 0.5460579866043902, "ABILIFY": 0.627255139024566, "ADALIMUMAB": 0.0405641239961704, "ADEMPAS": 0.6468943740152383, "ADENURIC": 0.5710689122928121, "AERIUS": 1.6463671337457484, "AFINITOR": 0.0488166770064846, "AGOMELATINE": 4.40874978521634, "AIMOVIG": 1.548755793572648, "ALEMTUZUMAB": 0.4830080431000127, "ALIMTA": 0.2142542840533956, "ALISKIREN": 0.5456630734309574, "AMIKACIN": 0.5245782025863357, "ANAGRELIDE": 5.578272728764781, "ANAKINRA": 0.514032141259493, "APIDRA": 0.2615236648204058, "APIXABAN": 0.1444103936618067, "APROVEL": 1.9924607065211069, "ARANESP": 0.1288209655973976, "ARAVA": 0.1147885290179273, "ARIPIPRAZOLE": 0.094545161749709, "ATAZANAVIR": 0.2376047273179511, "ATRIPLA": 0.064203477826788, "AUBAGIO": 0.6754548410616326, "AVANDIA": 0.1090570833294793, "AVASTIN": 0.281574662886132, "AZTREONAM": 1.779255357928756, "BENLYSTA": 0.2702461227465125, "BETMIGA": 1.3432683199816653, "BIKTARVY": 1.5269701107865337, "BONVIVA": 0.721647209061226, "BRILIQUE": 1.7410083658808106, "BRINTELLIX": 2.4630935310825586, "BRIVIACT": 1.1879014023068326, "BUDESONIDE": 0.0891987642271051, "BUPIVACAINE": 0.3095867433749427, "BUPRENORPHINE": 0.2715349082046884, "BYDUREON": 0.8288272012714656, "BYETTA": 0.2166863315291247, "CABOMETYX": 0.1290644614612259, "CANNABIDIOL": 1.2032768879859048, "CAPECITABINE": 0.2058875112937563, "CARBIDOPA": 3.554441695984958, "CELLCEPT": 0.1465546378980253, "CELSENTRI": 1.64476988993414, "CHAMPIX": 1.2116325273160584, "CICLOSPORIN": 0.0892860989975094, "CIMZIA": 0.1925637867940097, "CIRCADIN": 1.7407992281518714, "CLOPIDOGREL": 0.7228805936026732, "COAPROVEL": 2.464286669970026, "COLISTIMETHATE": 4.081051256129409, "COMBIVIR": 0.6813575792581184, "COMIRNATY": 1.7844482009482157, "COSENTYX": 0.3975025655804616, "CYMBALTA": 8.233390041761487, "DESCOVY": 0.7471783748430043, "DESLORATADINE": 1.262717676989054, "DEXAMETHASONE": 0.2814717770802148, "DULAGLUTIDE": 1.0123245650201529, "DULOXETINE": 0.5797899304297623, "EBIXA": 1.606156415309394, "EDURANT": 3.7775212085415726, "ELIQUIS": 0.6018804953438069, "ELLAONE": 0.860931818824416, "EMTRICITABINE": 1.114698291730146, "ENBREL": 0.1300530042676035, "ENTRESTO": 0.8786385461304139, "ENTYVIO": 0.338780698789879, "ENZALUTAMIDE": 0.8120603843636052, "EPCLUSA": 0.9435692355942074, "ERLEADA": 0.6688136683810247, "ESBRIET": 0.7901689839430441, "ESMYA": 2.849356552112286, "EUCREAS": 0.985546875400752, "EVISTA": 0.3616760657742936, "EVRA": 0.5526797668255069, "EXFORGE": 0.9946829310840958, "EXJADE": 0.1573912454479229, "EXVIERA": 0.5009331726307498, "EYLEA": 0.232261488819574, "FAMPYRA": 2.1145153757809405, "FASENRA": 0.4336709613423567, "FASLODEX": 0.5840763808940711, "FENTANYL": 0.0539934415998626, "FESOTERODINE": 3.2623678498331685, "FIASP": 0.4367606942226837, "FLEBOGAMMA": 0.4087101512469136, "FLUCELVAX": 1.465628018660295, "FORSTEO": 4.170485478139744, "FORXIGA": 0.7258079910592571, "FYCOMPA": 4.485276549107328, "GALAFOLD": 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2.2446032418181536, "KARVEZIDE": 3.800464072838746, "KEPPRA": 0.9188911839974444, "KESIMPTA": 0.4635549183683495, "KEYTRUDA": 0.1532911933910366, "KIOVIG": 0.6550860260833604, "KISQALI": 0.4540990832644556, "LACOSAMIDE": 0.9008722965750602, "LANTUS": 0.4142322982623133, "LEFLUNOMIDE": 0.7462427397521938, "LEMTRADA": 0.3741300069679478, "LEVEMIR": 0.2967285342129837, "LEVETIRACETAM": 0.3124876563978497, "LEVOFLOXACIN": 0.4791406440440903, "LIXIANA": 0.6268933534665249, "LYNPARZA": 0.2276571230363466, "LYRICA": 0.8004372015823341, "LYSODREN": 2.235873749672955, "MAVENCLAD": 1.4863805090671076, "MEKINIST": 0.1781655973581541, "MELATONIN": 2.7146910925770213, "MEMANTINE": 1.0056309145034374, "MENVEO": 1.5750345538941617, "MEPOLIZUMAB": 0.6824825189305092, "METHOTREXATE": 0.1172127661361078, "MICARDIS": 0.8639515686972993, "MICARDISPLUS": 3.2191524161022684, "MIMPARA": 0.8915378078350958, "MMRVAXPRO": 0.2622584626711801, "MODERNA": 2.1247053925457484, "MOVYMIA": 4.008758195843696, "NEULASTA": 0.2053936180929489, "NEXAVAR": 0.1389168368071952, "NIMENRIX": 0.9071862861628764, "NINLARO": 0.4021455267975069, "NORVIR": 0.6641728050239007, "NUCALA": 0.4097701726196766, "OCRELIZUMAB": 1.254550159661232, "OFEV": 0.4231080028083659, "OLANZAPINE": 0.2925383090991176, "OLYSIO": 0.6587577204372513, "OMALIZUMAB": 0.2258789657841334, "OPDIVO": 0.1317099762597837, "OPSUMIT": 0.1689152588115228, "PANTOPRAZOLE": 0.4003185628316043, "PEGASYS": 0.5799869164345492, "PEGINTERFERON": 0.676293404240128, "PEGINTRON": 0.472939665697682, "PLAVIX": 0.3877985648887014, "PLEGRIDY": 0.5777492696516611, "PREGABALIN": 0.8510698208959717, "PRIVIGEN": 0.4722497636056976, "PROTELOS": 1.4065326568533698, "RANEXA": 3.287332223961009, "RASILEZ": 0.3774770828989217, "REBETOL": 0.6667889828631889, "RELVAR": 0.281731645570509, "REVATIO": 0.1659787172978387, "RIBAVIRIN": 0.1547860375920294, "RINVOQ": 0.308977866063198, "RISPERIDONE": 0.903957391301205, "ROACTEMRA": 0.9776255138678712, "RYBELSUS": 0.4464636365680029, "SAXENDA": 0.6043107186635689, "SHINGRIX": 0.6923371168542637, "SIFROL": 1.5724660829203414, "SILDENAFIL": 0.499213510738945, "SILGARD": 6.382726178439767, "SIMPONI": 0.2861354312670148, "SOLIRIS": 0.1583509916144586, "SOVALDI": 0.3092274484962709, "SPIKEVAX": 1.072001233662828, "SPIRONOLACTONE": 0.4704316742572985, "SPRYCEL": 0.121978525050006, "STALEVO": 0.7648023196941655, "STELARA": 0.8649883400837006, "STRIBILD": 0.0701009911761473, "SUBOXONE": 0.1422188519745269, "SUTENT": 0.1838373258017286, "SYCREST": 0.8677002245956925, "TAMIFLU": 0.6821837463994359, "TASIGNA": 0.4607994273633195, "TERIPARATIDE": 1.8181826268868453, "THALIDOMIDE": 1.4779317503393965, "TIVICAY": 0.6507252125801499, "TOVIAZ": 1.4206292934425135, "TOZINAMERAN": 1.7605016458182234, "TRACLEER": 0.1335212598564806, "TRELEGY": 0.1689310171309036, "TREMFYA": 0.1853965865924016, "TRIUMEQ": 1.7917671122736267, "TRULICITY": 0.5915449423304953, "TRUVADA": 0.0187597496445955, "TWINRIX": 1.4538237016375943, "UROREC": 4.662874008234813, "VALDOXAN": 1.8127861831229763, "VAXZEVRIA": 1.3989967551591502, "VFEND": 0.256289862768966, "VIAGRA": 0.4776290988662967, "VICTOZA": 0.6812665231312278, "VIMPAT": 3.5528358129278304, "VOTRIENT": 0.3512581073697269, "XALKORI": 0.2750601656573329, "XARELTO": 0.2120481828341454, "XELJANZ": 0.3357409107513658, "XELODA": 0.3389532419570905, "XOLAIR": 0.5996341290686731, "XTANDI": 0.7491028108695716, "XYREM": 0.5682976308756146, "ZONEGRAN": 3.995681524225828, "ZOSTAVAX": 0.8101699840998288, "ZYPADHERA": 2.57662937836009, "ZYPREXA": 0.2324081086189262, "null": 1.0061548311018476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12621.json
new file mode 100644
index 00000000000..bcf3f798f70
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12621.json
@@ -0,0 +1 @@
+{"null": 0.8543727500275625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12622.json
new file mode 100644
index 00000000000..0857a269c8b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12622.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8827709579365846, "VAXZEVRIA": 1.092455960346885, "null": 1.694721013906438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12623.json
new file mode 100644
index 00000000000..bcee1d990fa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12623.json
@@ -0,0 +1 @@
+{"CELECOXIB": 20.696113086729703, "COMIRNATY": 2.907597197424005, "CYMBALTA": 0.6598932594270188, "DEXAMETHASONE": 1.5434342097630092, "FORSTEO": 1.4322487252529217, "GARDASIL": 0.7698483749312688, "SPIKEVAX": 1.8994162184516528, "STELARA": 1.114340186226369, "TOZINAMERAN": 2.157020512328101, "VAXZEVRIA": 1.674351903553753, "ZOSTAVAX": 3.678310220491765, "null": 0.3344946391712996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12624.json
new file mode 100644
index 00000000000..3982c4303f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12624.json
@@ -0,0 +1 @@
+{"null": 0.6842411932383017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12625.json
new file mode 100644
index 00000000000..a8b4ea352ed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12625.json
@@ -0,0 +1 @@
+{"null": 1.071196682677953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12626.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12626.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12627.json
new file mode 100644
index 00000000000..d8e0d843270
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12627.json
@@ -0,0 +1 @@
+{"null": 2.297448547694354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12628.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12628.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12629.json
new file mode 100644
index 00000000000..9e36c29470d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12629.json
@@ -0,0 +1 @@
+{"null": 1.037185294654559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1263.json
index d9b5f29cd31..c9c31360fd7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1263.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1263.json
@@ -1 +1 @@
-{"BRAFTOVI": 31.109559251423097, "JARDIANCE": 4.097554443824843, "KEPPRA": 42.373009872605486, "OPSUMIT": 4.88957517049012, "VIMPAT": 50.2115798337618, "null": 1.2178732064922917}
\ No newline at end of file
+{"COMIRNATY": 2.76213548098781, "VAXZEVRIA": 1.143243760740252, "null": 0.3593913290808957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12630.json
new file mode 100644
index 00000000000..21a8b709818
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12630.json
@@ -0,0 +1 @@
+{"null": 0.7673534021882098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12631.json
new file mode 100644
index 00000000000..ee640751074
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12631.json
@@ -0,0 +1 @@
+{"null": 1.9001059167326195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12632.json
new file mode 100644
index 00000000000..4d9d4adaba1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12632.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 19.23301268817037, "PLAVIX": 20.92272383545631, "null": 1.2533913376355132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12633.json
new file mode 100644
index 00000000000..a273a9f28d1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12633.json
@@ -0,0 +1 @@
+{"PLAVIX": 16.522763769161774, "null": 1.7007882201577793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12634.json
new file mode 100644
index 00000000000..fc51188987e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12634.json
@@ -0,0 +1 @@
+{"null": 5.761787127087694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12635.json
new file mode 100644
index 00000000000..96d01983cd5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12635.json
@@ -0,0 +1 @@
+{"null": 2.1811474582026085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12636.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12636.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12637.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12637.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12638.json
new file mode 100644
index 00000000000..7a6b208257f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12638.json
@@ -0,0 +1 @@
+{"AIMOVIG": 6.497473839380626, "CELECOXIB": 43.78855048876494, "CHAMPIX": 2.1797978962936613, "COMIRNATY": 1.380182638173162, "CYMBALTA": 1.3855342332688845, "DEXAMETHASONE": 3.2386727337666903, "SPIKEVAX": 0.8274798816239602, "TOZINAMERAN": 1.4624320572650185, "VAXZEVRIA": 0.6020562335779032, "null": 0.841901112700177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12639.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12639.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1264.json
index 7fc253b62a0..15b19fccee4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1264.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1264.json
@@ -1 +1 @@
-{"CELECOXIB": 99.49787068154076, "ESOMEPRAZOLE": 370.049138546544, "null": 1.224404897372263}
\ No newline at end of file
+{"null": 0.4463192061723124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12640.json
new file mode 100644
index 00000000000..0a2516adc9b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12640.json
@@ -0,0 +1 @@
+{"AIMOVIG": 14.54608330956562, "COMIRNATY": 1.1511588192689524, "SPIKEVAX": 0.5234850535998931, "TOZINAMERAN": 6.914311924698451, "VAXZEVRIA": 2.083365352413132, "null": 0.194393498526488}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12641.json
new file mode 100644
index 00000000000..f9cba0e4bb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12641.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.591276922453304, "MODERNA": 2.743255666796249, "SHINGRIX": 2.024564978362966, "SPIKEVAX": 1.9253580216779853, "TOZINAMERAN": 2.0577676357140224, "VAXZEVRIA": 1.2811820212324256, "ZOSTAVAX": 2.464223955727773, "null": 0.1187410870526104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12642.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12642.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12643.json
new file mode 100644
index 00000000000..301849cc3c1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12643.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8798573920970705, "null": 0.4006700021480839}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12644.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12644.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12645.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12645.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12646.json
new file mode 100644
index 00000000000..b66e7dd6d1a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12646.json
@@ -0,0 +1 @@
+{"SUBOXONE": 65.31846355589512, "null": 0.9498247013157272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12647.json
new file mode 100644
index 00000000000..4abeb6bc103
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12647.json
@@ -0,0 +1 @@
+{"null": 10.93426116620332}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12648.json
new file mode 100644
index 00000000000..5546faecb37
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12648.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 113.02323698344291, "null": 1.3270481012813211}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12649.json
new file mode 100644
index 00000000000..92de9ffb4f0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12649.json
@@ -0,0 +1 @@
+{"SUBOXONE": 76.68994418069478, "null": 1.0750198134476086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1265.json
index 1c0c4d70498..f5f554be82f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1265.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1265.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 15.619204457777888, "ELIQUIS": 26.52218687800658, "NEXAVAR": 8.327588874693083, "PEGASYS": 2.251000747453597, "PLAVIX": 9.950861928007686}
\ No newline at end of file
+{"null": 0.6819504044407018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12650.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12650.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12651.json
new file mode 100644
index 00000000000..80f3ffbf19b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12651.json
@@ -0,0 +1 @@
+{"null": 3.872603199313157}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12652.json
new file mode 100644
index 00000000000..3a0cb2da9ba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12652.json
@@ -0,0 +1 @@
+{"SUBOXONE": 36.79064168628207, "null": 4.3267917064445465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12653.json
new file mode 100644
index 00000000000..aae1e771c83
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12653.json
@@ -0,0 +1 @@
+{"ABILIFY": 6.048001234188121, "CHAMPIX": 54.3131394415617, "CYMBALTA": 2.836753572933254, "LATUDA": 10.704638481319, "OLANZAPINE": 7.464385334260461, "PEGASYS": 4.367869339207155, "PEGINTRON": 3.662840562905101, "null": 2.2880767620880373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12654.json
new file mode 100644
index 00000000000..6d481889e44
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12654.json
@@ -0,0 +1 @@
+{"ABACAVIR": 8.725279691354764, "ALEMTUZUMAB": 100.56153201173872, "ASPARAGINASE": 119.14962675355363, "BIKTARVY": 222.2101632400498, "CICLOSPORIN": 4.520490753117547, "CYMBALTA": 4.337385675288381, "CYTARABINE": 18.039951093088472, "DARUNAVIR": 35.727451482308105, "MELPHALAN": 69.34003307326786, "PEGINTERFERON": 12.363230589761692, "null": 0.1073484176624703}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12655.json
new file mode 100644
index 00000000000..c950b58c2ed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12655.json
@@ -0,0 +1 @@
+{"PREGABALIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12656.json
new file mode 100644
index 00000000000..b62b4076d2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12656.json
@@ -0,0 +1 @@
+{"ENTRESTO": 57.868689420113824, "null": 0.3254352811211629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12657.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12657.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12658.json
new file mode 100644
index 00000000000..e604aeca412
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12658.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 25.51175571293593, "ASPARAGINASE": 20.089670572403808, "BUSULFAN": 247.14721385163972, "CELLCEPT": 26.348549596757515, "CICLOSPORIN": 51.04483396474568, "METHOTREXATE": 8.12410615184938, "MYCOPHENOLATE": 86.586966690326, "null": 0.206051816514096}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12659.json
new file mode 100644
index 00000000000..15b19fccee4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12659.json
@@ -0,0 +1 @@
+{"null": 0.4463192061723124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1266.json
index cd16fc731b9..4f415774b10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1266.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1266.json
@@ -1 +1 @@
-{"AVANDIA": 11.845639041941055, "COMIRNATY": 1.389385321157707, "ELIQUIS": 1.5889430986358817, "EYLEA": 9.13342428930855, "FORXIGA": 15.07737908596566, "JARDIANCE": 2.801404525076701, "NEXAVAR": 3.117070165763841, "VAXZEVRIA": 1.1800251507489623}
\ No newline at end of file
+{"COMIRNATY": 0.4479323357850973, "IBRANCE": 9.279682911532085, "JAKAVI": 47.12477992299383, "RUXOLITINIB": 93.88774821125796, "null": 0.4170420449843898}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12660.json
new file mode 100644
index 00000000000..ec64348de64
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12660.json
@@ -0,0 +1 @@
+{"ADEFOVIR": 24.28293418155065, "AFINITOR": 0.3458368088282633, "AIMOVIG": 0.3547533897121263, "ALEMTUZUMAB": 2.594396593850773, "ANAKINRA": 1.157223749439937, "ARANESP": 0.8065431980342176, "ARAVA": 0.1936176223408561, "ASPARAGINASE": 27.161805730258617, "AUBAGIO": 0.5767169079806069, "AZATHIOPRINE": 2.283018067032186, "BEDAQUILINE": 1.2599464982237412, "BENLYSTA": 3.36515911267273, "BUDESONIDE": 0.3819255964409541, "BUSULFAN": 5.556610952254267, "BYDUREON": 0.5031116569965385, "BYETTA": 0.6696012137884482, "CELLCEPT": 4.28558073880074, "CHAMPIX": 0.7373673971889021, "CICLOSPORIN": 3.10694214455313, "CIMZIA": 1.5982282314992882, "COMBIVIR": 1.012991264191845, "COMIRNATY": 0.2071618682928629, "COSENTYX": 1.7586032349482807, "CYMBALTA": 0.301148819712161, "CYTARABINE": 2.0753429258254905, "DEXAMETHASONE": 0.9952888910945744, "ELIQUIS": 0.2724074204920705, "ENBREL": 2.822364790747432, "ENTRESTO": 0.9177072277082484, "ENTYVIO": 1.70947070942001, "ESBRIET": 1.3183807775377694, "EXJADE": 2.1822166174237823, "FAMPYRA": 1.90978417683058, "FASENRA": 3.73364438327422, "FASLODEX": 0.5183633934608136, "FILGRASTIM": 4.9977116655340055, "FIRDAPSE": 4.3644019595714205, "FORSTEO": 0.518602043957676, "GARDASIL": 4.218242778195194, "HEPSERA": 3.203725538308833, "HIZENTRA": 4.498124933676181, "HUMALOG": 1.712077442262628, "IBRANCE": 1.731776428362639, "IBUPROFEN": 0.5294451142960505, "ICLUSIG": 1.2799577657636478, "INCRUSE": 3.357708832804083, "INFANRIX": 4.231417485719541, "IRON": 3.5642238684080048, "JAKAVI": 1.3843951554617628, "JANUMET": 0.6235537712481007, "JARDIANCE": 0.782367066526004, "KAFTRIO": 6.681906169537426, "KALETRA": 1.107124339831188, "KALYDECO": 12.728518357098013, "KEPPRA": 0.8961754097704406, "KEYTRUDA": 0.1995131364317384, "LANTUS": 0.914781281780948, "LEMTRADA": 1.5045278444838823, "LEVEMIR": 0.7805787281836497, "LYRICA": 0.8976942738503472, "MENVEO": 3.609901953220176, "MEPOLIZUMAB": 7.503347980204133, "MERCAPTOPURINE": 4.008189660591511, "METHOTREXATE": 2.746027345086657, "MMRVAXPRO": 2.170415844695514, "NAGLAZYME": 5.774838559797415, "NIMENRIX": 0.9328571720153274, "NPLATE": 2.617038220945177, "NUCALA": 2.2812476905953667, "OCALIVA": 2.96029910183373, "OLANZAPINE": 0.265689871758028, "OMALIZUMAB": 1.4151119144641064, "OPSUMIT": 2.1648277687642583, "ORENCIA": 10.3124694356457, "ORKAMBI": 9.85631440855826, "PEGASYS": 1.350239834626192, "PEGINTERFERON": 1.1385851543389671, "PEGINTRON": 0.7371374266268526, "PLAVIX": 0.4340120517685963, "PLEGRIDY": 1.6115519358361263, "PREVENAR": 10.483410532892169, "RAPAMUNE": 2.899650736491915, "REVATIO": 1.4574255629696966, "RINVOQ": 1.7336501462224827, "RITUXIMAB": 0.8063982958479411, "ROACTEMRA": 1.3807219330466691, "ROTATEQ": 3.917497209711664, "RUBRACA": 1.59078498946069, "SHINGRIX": 0.4251414684011773, "SIMPONI": 8.30195496506259, "SOLIRIS": 8.245395768988486, "SOMATROPIN": 4.7167327495039295, "SPIKEVAX": 0.122975933204997, "SPINRAZA": 13.003892029886169, "SPRYCEL": 1.0392284380229402, "STELARA": 2.695894335843977, "SUTENT": 1.061907912933487, "SYNAGIS": 20.80593853914922, "TOZINAMERAN": 0.4714291891898464, "TRACLEER": 3.599241436131178, "TRELEGY": 2.94622891874447, "TREMFYA": 1.1599315195983289, "TWINRIX": 1.6724807286758618, "VAXZEVRIA": 0.1338609516770411, "VELTASSA": 2.1320334894862145, "VFEND": 1.8604347105440453, "VIAGRA": 0.5176316043960606, "VICTOZA": 1.2042308001938649, "XELJANZ": 4.501203404152633, "XOLAIR": 4.297590070120743, "XTANDI": 0.4011054954164078, "ZOSTAVAX": 1.4195161228564477, "ZYPREXA": 0.2874458156023598, "null": 0.9527663206111152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12661.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12661.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12662.json
new file mode 100644
index 00000000000..17ac052abcf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12662.json
@@ -0,0 +1 @@
+{"BIKTARVY": 170.87287612535974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12663.json
new file mode 100644
index 00000000000..7236ea2bbea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12663.json
@@ -0,0 +1 @@
+{"BIKTARVY": 663.6979522012074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12664.json
new file mode 100644
index 00000000000..007670fbeaa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12664.json
@@ -0,0 +1 @@
+{"BIKTARVY": 137.51745744674574, "COMBIVIR": 237.65736056839475, "PEGASYS": 16.132272360540007}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12665.json
new file mode 100644
index 00000000000..aed883e2131
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12665.json
@@ -0,0 +1 @@
+{"ABACAVIR": 4.006606114955514, "ADEFOVIR": 155.48106806424838, "ATAZANAVIR": 24.18031807008479, "ATRIPLA": 2.9370126841808157, "BARACLUDE": 166.47896318073563, "BIKTARVY": 128.68420443678886, "CABOTEGRAVIR": 207.0862112670229, "CELLCEPT": 1.0308737613397652, "CICLOSPORIN": 0.8925255627298908, "COMBIVIR": 7.794316609638822, "DAKLINZA": 12.881783917569264, "DARUNAVIR": 26.819489002087117, "DESCOVY": 43.65226576249108, "DOLUTEGRAVIR": 25.150319199271856, "EFAVIRENZ": 26.47656970226932, "EMTRICITABINE": 18.884105716020542, "ENTECAVIR": 102.31203578379056, "GANCICLOVIR": 15.384479018341914, "GENVOYA": 124.54115527873388, "HARVONI": 5.1893987753290105, "HEPSERA": 73.73402075593185, "INCIVO": 13.896632287420111, "ISENTRESS": 10.07428098957922, "KALETRA": 25.403195502780825, "LAMIVUDINE": 8.295727128053338, "NORVIR": 18.752262737242443, "OLYSIO": 40.2837904915344, "PEGASYS": 22.90058888141333, "PEGINTERFERON": 6.039716537112199, "PEGINTRON": 3.5837865174260566, "REKAMBYS": 155.6588293864485, "REYATAZ": 38.12423962785753, "RIBAVIRIN": 13.45464430674092, "SOVALDI": 23.913711484866848, "STRIBILD": 9.588219359523416, "SYMTUZA": 104.16448448730864, "TENOFOVIR": 51.89174899445597, "TIVICAY": 42.6312920656961, "TRIUMEQ": 21.478645110576345, "TRUVADA": 4.756791089592164, "VEMLIDY": 72.46452354431024, "VIREAD": 62.40505438352553, "null": 0.0316622046386988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12666.json
new file mode 100644
index 00000000000..1d3cb1387e8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12666.json
@@ -0,0 +1 @@
+{"ABACAVIR": 77.8069111877787, "ATAZANAVIR": 64.95070160605133, "ATRIPLA": 0.8685842483342745, "BIKTARVY": 17.591802484957203, "CABOTEGRAVIR": 277.00556144659186, "CELSENTRI": 91.43272044930563, "COMBIVIR": 13.018284079113114, "DACLATASVIR": 149.25009093444734, "DAKLINZA": 77.95247564998206, "DARUNAVIR": 142.20989885177767, "DOLUTEGRAVIR": 183.7559197868926, "EFAVIRENZ": 62.81485457310976, "EMTRICITABINE": 48.289062039213576, "ENTECAVIR": 71.60971291362493, "GANCICLOVIR": 35.3663445773665, "HARVONI": 94.03920278309782, "HEPSERA": 52.85393391499872, "ISENTRESS": 21.05208904616732, "LAMIVUDINE": 118.0984434626281, "OLYSIO": 12.719277201096364, "RIBAVIRIN": 28.356824525381988, "STRIBILD": 7.4161622485859, "TIVICAY": 23.3951337681442, "TRUVADA": 1.8230300634823915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12667.json
new file mode 100644
index 00000000000..3c023265c04
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12667.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9516773640186504, "TOZINAMERAN": 1.480705259386807, "null": 0.6345223011000408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12668.json
new file mode 100644
index 00000000000..99fd56cc98d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12668.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1732807086279946, "null": 0.3927857668761199}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12669.json
new file mode 100644
index 00000000000..97763886794
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12669.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8669328224602373, "TOZINAMERAN": 2.639525593829867, "VAXZEVRIA": 1.0348148429732993, "null": 0.6899201532030836}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1267.json
index d64082852a0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1267.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1267.json
@@ -1 +1 @@
-{"AVANDIA": 9.931168679544324, "AZILECT": 232.4543451655005, "DARUNAVIR": 164.40142667332285}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12670.json
new file mode 100644
index 00000000000..16e7e118ec7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12670.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6538190160382159, "SPIKEVAX": 0.3951125925751305, "TOZINAMERAN": 2.634800219569762, "VAXZEVRIA": 1.4928627749217154, "null": 0.7020718856774002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12671.json
new file mode 100644
index 00000000000..a2e1d245139
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12671.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 38.20956384999442, "PEGASYS": 4.785999630580513, "null": 0.2742989718685756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12672.json
new file mode 100644
index 00000000000..6011d6b78e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12672.json
@@ -0,0 +1 @@
+{"HUMIRA": 245.76751199863844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12673.json
new file mode 100644
index 00000000000..c21d0f4f251
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12673.json
@@ -0,0 +1 @@
+{"ABATACEPT": 3.7438171623697754, "ARAVA": 2.5322564082930583, "ENBREL": 4.543674782510658, "RITUXIMAB": 8.734705070048902, "SOLIRIS": 6.554397993441625, "SPINRAZA": 18.891870948840715, "SYNAGIS": 14.998847410228054, "XELJANZ": 4.731286894412238, "null": 0.6447521865308388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12674.json
new file mode 100644
index 00000000000..2a846e1a0fe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12674.json
@@ -0,0 +1 @@
+{"TESTOSTERONE": 925.5841314939246, "null": 1.211868660627016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12675.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12675.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12676.json
new file mode 100644
index 00000000000..3f1c6d494a3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12676.json
@@ -0,0 +1 @@
+{"ABACAVIR": 50.577737318825946, "ATAZANAVIR": 103.8921721481632, "ATRIPLA": 2.063980447975663, "BARACLUDE": 56.15312567319019, "BIKTARVY": 29.66360819641498, "CABOTEGRAVIR": 307.8958115495183, "CELSENTRI": 42.95093565629815, "COMBIVIR": 7.704339649386891, "COMIRNATY": 0.0178306301263039, "CYTARABINE": 1.808166912986361, "DACLATASVIR": 106.23972147270464, "DAKLINZA": 30.535854944315773, "DARUNAVIR": 137.27391245378325, "DESCOVY": 30.98274301988402, "DOLUTEGRAVIR": 213.4464445613229, "EFAVIRENZ": 100.4913544220476, "EMTRICITABINE": 55.0722778670858, "EMTRIVA": 45.5129816677031, "ENTECAVIR": 57.82476222836497, "EPCLUSA": 11.769276594698924, "EPIVIR": 7.575623127779882, "GENVOYA": 48.04037800029135, "HARVONI": 14.99916011346792, "HEPSERA": 12.064851630748649, "INCIVO": 5.280518751635785, "ISENTRESS": 14.319505325570091, "KALETRA": 4.068130752470712, "LAMIVUDINE": 70.34159354173681, "LOPINAVIR": 20.18505914278913, "NEVIRAPINE": 46.82189593573251, "OLYSIO": 12.010557119057042, "PEGASYS": 2.1131899223825954, "PEGINTERFERON": 15.943060221728189, "REKAMBYS": 251.4775160400662, "RIBAVIRIN": 62.376829354287736, "SOVALDI": 24.4060372416836, "STRIBILD": 8.415654762306158, "TIVICAY": 13.700562716154405, "TRIUMEQ": 16.189584049400146, "TRUVADA": 1.92480926905267, "VIREAD": 8.64454321459482, "ZEPATIER": 84.34085865790985, "null": 0.0707972519316132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12677.json
new file mode 100644
index 00000000000..241721ded2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12677.json
@@ -0,0 +1 @@
+{"null": 2.201873852535795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12678.json
new file mode 100644
index 00000000000..eae07489927
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12678.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 35.791905699531085, "null": 0.1580549196378231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12679.json
new file mode 100644
index 00000000000..f45524a2e2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12679.json
@@ -0,0 +1 @@
+{"null": 2.790893158746566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1268.json
index 3a114d5f55a..7a81a398935 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1268.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1268.json
@@ -1 +1 @@
-{"null": 1.695797243940256}
\ No newline at end of file
+{"OMALIZUMAB": 196.92701971740385, "SPIKEVAX": 4.137830142011464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12680.json
new file mode 100644
index 00000000000..699f8e5391d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12680.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.06962461970136, "VAXZEVRIA": 1.1543558322784802, "null": 0.7393375026990332}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12681.json
new file mode 100644
index 00000000000..129a73aa81d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12681.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7774996551981915, "VAXZEVRIA": 8.818517865247335}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12682.json
new file mode 100644
index 00000000000..9fbbc8f4b40
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12682.json
@@ -0,0 +1 @@
+{"null": 1.7094405736763596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12683.json
new file mode 100644
index 00000000000..709df37bd57
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12683.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12684.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12684.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12685.json
new file mode 100644
index 00000000000..81f6a9f223b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12685.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.4034908700476878, "AFLIBERCEPT": 23.507422507729093, "AMINOSALICYLIC": 0.6830984184370321, "APIDRA": 0.6028259321430967, "ARIPIPRAZOLE": 0.4544341810994426, "ATRIPLA": 0.0670665367160753, "AVAMYS": 1.6337555392105971, "AVANDIA": 0.9967957813718724, "AVASTIN": 3.6872517529573248, "AZOPT": 16.361061148031908, "BELANTAMAB": 74.72834515800422, "BEOVU": 148.50758408819283, "BETAFERON": 1.893306650745608, "BEVACIZUMAB": 0.827005995880051, "BLENREP": 316.1880632821686, "BRAFTOVI": 2.335364373805172, "BROLUCIZUMAB": 129.35655425693488, "BYDUREON": 0.823321480590984, "CELLCEPT": 1.226272945768388, "CHAMPIX": 0.8841603332262441, "CICLOSPORIN": 1.8885110639687013, "CLOPIDOGREL": 0.2289387764962063, "COMBIVIR": 2.0797661191021044, "COMIRNATY": 0.4199097177181425, "CYMBALTA": 0.4208747484502552, "CYTARABINE": 0.7119879160658587, "DARZALEX": 1.2625991529655611, "DEXAMETHASONE": 2.289041602109572, "ELIQUIS": 0.2329166663993569, "EVISTA": 2.3882654895133584, "EXFORGE": 0.8377060309676935, "EXJADE": 1.0771037860012322, "EYLEA": 106.81590775761602, "FENTANYL": 0.7398180006394516, "FLORAJEN": 336.0945697421141, "GARDASIL": 1.1155896939708252, "HUMALOG": 2.261748824042095, "IBRANCE": 0.3472041969429592, "INTRONA": 2.6690351352316832, "JETREA": 313.8552977799534, "KEPPRA": 0.3926847479634244, "KEYTRUDA": 0.6462653599865318, "LAMIVUDINE": 2.25264336248127, "LANTUS": 1.7496314975872285, "LEVETIRACETAM": 0.42112377289355, "LEVOFLOXACIN": 0.6378342053425008, "LUCENTIS": 38.290648912713706, "LYRICA": 0.9374923031908357, "MEKINIST": 2.6032711069643195, "MICARDIS": 0.8415901853327946, "MODERNA": 0.6426412316415467, "MYCOPHENOLATE": 3.874615816425727, "NEPAFENAC": 76.68996211924863, "NEVANAC": 32.78119662924404, "OLANZAPINE": 0.2927528465594836, "PEGASYS": 1.5510442022647553, "PEGINTERFERON": 2.4734504262372723, "PEGINTRON": 2.2511329986056112, "PLAVIX": 0.200175799349766, "REBETOL": 3.059559508233645, "REVATIO": 1.699403635468253, "RINVOQ": 0.74960833562555, "ROACTEMRA": 0.7088951633770028, "SAXENDA": 0.715445204768012, "SILDENAFIL": 3.8872870043724688, "SIMPONI": 0.4720088760386233, "SPIKEVAX": 0.239620215279687, "STELARA": 0.3177531991449221, "SUTENT": 0.2246834636949617, "TASIGNA": 1.151018554866093, "TOBRAMYCIN": 5.19426476495989, "TOVIAZ": 1.288125381756111, "TOZINAMERAN": 0.2999516989414877, "TWINRIX": 1.4546000061636737, "VAXZEVRIA": 0.213685332594213, "VFEND": 5.0568752964547246, "VIAGRA": 5.984875990811678, "VIGABATRIN": 16.361061148031908, "VORICONAZOLE": 1.5335627576169846, "XELJANZ": 0.5907641473963964, "ZOSTAVAX": 0.6257198174288431, "ZYPREXA": 0.5301098992350616, "null": 1.2762572139797352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12686.json
new file mode 100644
index 00000000000..576bf1d09c5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12686.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.225274108939182, "EYLEA": 205.05239809757876, "JETREA": 569.8555452218397, "null": 2.580031352832058}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12687.json
new file mode 100644
index 00000000000..265062e048e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12687.json
@@ -0,0 +1 @@
+{"null": 1.5019579546637485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12688.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12688.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12689.json
new file mode 100644
index 00000000000..8545f359770
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12689.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3143215708316158, "VFEND": 37.90209187304908, "VIAGRA": 84.09992242207515, "null": 0.432108358878867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1269.json
index 99c944e5c7f..b1b9e5205cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1269.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1269.json
@@ -1 +1 @@
-{"COMIRNATY": 1.06769731171878}
\ No newline at end of file
+{"IBRANCE": 17.461799739212235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12690.json
new file mode 100644
index 00000000000..a70aa16883b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12690.json
@@ -0,0 +1 @@
+{"KESIMPTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12691.json
new file mode 100644
index 00000000000..64f4f609460
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12691.json
@@ -0,0 +1 @@
+{"null": 0.8080245494647719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12692.json
new file mode 100644
index 00000000000..1058a05b5d4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12692.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12693.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12693.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12694.json
new file mode 100644
index 00000000000..4a066cc5760
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12694.json
@@ -0,0 +1 @@
+{"null": 1.181174239710313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12695.json
new file mode 100644
index 00000000000..8ecbf3c431c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12695.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 3.506080805167576, "ABATACEPT": 0.4028749154240452, "ABILIFY": 0.6954253920522953, "ACTOS": 0.687712440341427, "ACTRAPID": 0.8475807407660139, "ADALIMUMAB": 0.2431642730526917, "ADCIRCA": 0.3406176922862128, "AERIUS": 0.4452473194159939, "AFINITOR": 0.1583646980576844, "AIMOVIG": 1.0378115472709355, "ALEMTUZUMAB": 0.456830727503871, "ALIMTA": 0.221758116755173, "ALL": 1.025639118805382, "AMIKACIN": 0.8552876867253021, "AMINOSALICYLIC": 0.426113766042838, "ANAKINRA": 0.150662292841892, "ANORO": 0.692380854614581, "APIDRA": 4.669958916091689, "APIXABAN": 0.4273583853809627, "APROVEL": 1.3421509495374455, "ARAVA": 0.6945436477718234, "ARIPIPRAZOLE": 0.1615883185981678, "ASPARAGINASE": 0.334184493386551, "ATRIPLA": 0.0254629388349918, "AUBAGIO": 2.444615497694567, "AVAMYS": 1.0894684653548456, "AVANDAMET": 0.7561123022295064, "AVANDIA": 0.9352335587379712, "AVASTIN": 1.2337942671830946, "AZATHIOPRINE": 0.4288564768623788, "AZOPT": 5.181402587196589, "BEDAQUILINE": 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0.478848578017974, "RYBELSUS": 1.1451632190530336, "SAXENDA": 0.4956331855764749, "SHINGRIX": 0.7499867029022006, "SIFROL": 1.3038221521615914, "SILDENAFIL": 1.9574401158485888, "SIMPONI": 0.7565504705101739, "SOLIRIS": 0.3063309617503256, "SOVALDI": 0.4143427417398953, "SPIKEVAX": 0.7304180510406079, "SPRYCEL": 0.4695432985937019, "STALEVO": 0.6018753479827705, "STELARA": 0.6439627539430544, "STIVARGA": 0.1819188890596316, "STRIBILD": 0.0450944853676502, "SUBOXONE": 0.4124642597315282, "SUTENT": 0.3256761519356949, "SYCREST": 0.7831298459083961, "TAFINLAR": 1.419254859674084, "TAGRISSO": 0.5265748017971522, "TAMIFLU": 0.985078993088892, "TASIGNA": 0.4668682075007406, "TELMISARTAN": 0.7532357361532033, "TEMODAL": 0.4375615913519701, "TEMOZOLOMIDE": 0.4309790112282634, "TERIFLUNOMIDE": 1.4170933759625124, "THALIDOMIDE": 0.5269917805125357, "THIOTEPA": 6.677342690487749, "TIKOSYN": 3.519889071561064, "TOBRAMYCIN": 0.936768340222908, "TOUJEO": 5.016017648068181, "TOVIAZ": 1.7529392887811572, "TOZINAMERAN": 0.7429913483223409, "TRACLEER": 0.0811721345263853, "TRELEGY": 1.2969392220646672, "TREMFYA": 0.2578814695759383, "TRESIBA": 0.8447930431634019, "TRIUMEQ": 0.4497497796737388, "TRULICITY": 1.1352288732494615, "TRUVADA": 0.0281786281477698, "TWINRIX": 1.9943872264668543, "UROREC": 1.675633739548722, "VAXZEVRIA": 0.6862303321468564, "VFEND": 8.021913558434237, "VIAGRA": 4.79238179223219, "VICTOZA": 0.7220950024648, "VIGABATRIN": 1.7807420489098682, "VIMPAT": 0.7967816122550329, "VORICONAZOLE": 4.336999119729569, "VOTRIENT": 0.6461019711924387, "XALKORI": 5.382014105059722, "XARELTO": 0.3320642072804611, "XELJANZ": 1.0887643290646432, "XELODA": 0.3059171716931794, "XOLAIR": 0.4952368097908038, "XTANDI": 0.9158584575395364, "XYREM": 0.4731665229817739, "YERVOY": 0.4677681168304298, "ZELBORAF": 0.9559209994832384, "ZOSTAVAX": 0.8136352577804866, "ZYPADHERA": 0.2220112838775382, "ZYPREXA": 0.729094897174812, "null": 1.113334108435889}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12696.json
new file mode 100644
index 00000000000..8cc76c4a7bd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12696.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5461452753968877, "null": 1.6537816266283645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12697.json
new file mode 100644
index 00000000000..201e2b05572
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12697.json
@@ -0,0 +1 @@
+{"null": 3.350616664085944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12698.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12698.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12699.json
new file mode 100644
index 00000000000..b4e00d50c32
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12699.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.3829442609078677, "TOZINAMERAN": 3.536369558146257, "null": 1.0619548201141804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/127.json
index e6d769beed6..acfe7238125 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/127.json
@@ -1 +1 @@
-{"AZACITIDINE": 18.82969268886989, "COSENTYX": 3.291637019025799, "FILGRASTIM": 49.66079651931088, "NEULASTA": 19.18093011000357, "PEGASYS": 1.6833954525535046, "SPRYCEL": 6.634634804836901, "null": 1.3895488407541294}
\ No newline at end of file
+{"null": 2.386097647336676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1270.json
index b03409a6efb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1270.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1270.json
@@ -1 +1 @@
-{"COMIRNATY": 4.009885461607158, "SPIKEVAX": 13.972936893647397}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12700.json
new file mode 100644
index 00000000000..31287b171c8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12700.json
@@ -0,0 +1 @@
+{"null": 2.88677152477758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12701.json
new file mode 100644
index 00000000000..69e7fc98303
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12701.json
@@ -0,0 +1 @@
+{"null": 6.129413743496753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12702.json
new file mode 100644
index 00000000000..684c195de54
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12702.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 92.33591239843228, "AVAMYS": 33.687069435232296, "BUDESONIDE": 36.49460458161921, "MEPOLIZUMAB": 33.78561988950926, "NUCALA": 37.20407930802459, "SPINRAZA": 66.0556316173409, "null": 0.5010525688667302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12703.json
new file mode 100644
index 00000000000..a69846ea5de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12703.json
@@ -0,0 +1 @@
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12704.json
new file mode 100644
index 00000000000..00eb000c4cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12704.json
@@ -0,0 +1 @@
+{"SOMAVERT": 721.8178136516517, "null": 1.0884988106193223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12705.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12705.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12706.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12706.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12707.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12707.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12708.json
new file mode 100644
index 00000000000..b2bed5576ee
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12708.json
@@ -0,0 +1 @@
+{"KAFTRIO": 1523.5665143061224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12709.json
new file mode 100644
index 00000000000..73c73ce2d40
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12709.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": 11.322434738604157, "null": 0.9426267411580462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1271.json
index 88dbb8bf672..ea7183e221e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1271.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1271.json
@@ -1 +1 @@
-{"SOLIRIS": 1446.759529463025}
\ No newline at end of file
+{"ABILIFY": 0.7331897762247527, "AMBRISENTAN": 7.034340330039236, "APIDRA": 1.3468183821285389, "ARAVA": 0.8551222466501595, "ATRIPLA": 0.1022273121979814, "AUBAGIO": 1.5132696190233916, "BENLYSTA": 2.5178329136492925, "BUDESONIDE": 0.6098116829435052, "CHAMPIX": 1.463704879942372, "CIMZIA": 0.3555674674475949, "COMIRNATY": 1.389400132417259, "CYMBALTA": 0.431649322020119, "ELIQUIS": 1.161146245691762, "ENBREL": 1.323714870464574, "EXFORGE": 1.0387266328963716, "GARDASIL": 2.327442938541424, "HIZENTRA": 1.2934608826998812, "HUMIRA": 0.8400819135653839, "IBRANCE": 0.5885677728017035, "JANUMET": 0.6791734845009454, "JANUVIA": 0.7567873056858019, "JARDIANCE": 1.0103195647995835, "KEPPRA": 0.4343222928936484, "KEYTRUDA": 0.4180465108582231, "LANTUS": 2.9810114919536, "LEVEMIR": 0.9305858069600736, "LEVOFLOXACIN": 0.4194007877223742, "LYRICA": 2.221726217421444, "NEXAVAR": 0.621499952854038, "NUCALA": 1.471278906418631, "OLANZAPINE": 0.6540545577262682, "OPSUMIT": 0.893261108994298, "PEGASYS": 0.9129927153644068, "PEGINTRON": 1.043658638717727, "PLAVIX": 0.2776960188008745, "SHINGRIX": 7.994403003829035, "SIMPONI": 3.3756721305802397, "SPIKEVAX": 1.8669370066840447, "STELARA": 0.3622502217423191, "SUBOXONE": 0.6623702836818872, "SUTENT": 1.3067654409552594, "TOZINAMERAN": 1.2095469965620351, "TRELEGY": 0.8488189805527943, "TWINRIX": 2.017999925391984, "VAXZEVRIA": 1.0697393796459311, "XELJANZ": 1.1751750281379851, "XOFIGO": 2.8851654539730327, "XTANDI": 2.6162967607047487, "ZOSTAVAX": 0.364565474579104, "null": 0.7170118111608665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12710.json
new file mode 100644
index 00000000000..a4731040605
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12710.json
@@ -0,0 +1 @@
+{"null": 2.2164396055396938}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12711.json
new file mode 100644
index 00000000000..7d593a731c1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12711.json
@@ -0,0 +1 @@
+{"null": 1.1998650387085703}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12712.json
new file mode 100644
index 00000000000..15b19fccee4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12712.json
@@ -0,0 +1 @@
+{"null": 0.4463192061723124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12713.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12713.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12714.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12714.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12715.json
new file mode 100644
index 00000000000..b755d36cd32
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12715.json
@@ -0,0 +1 @@
+{"CARBIDOPA": 228.19029553873088, "CELECOXIB": 34.9094075788953, "COMIRNATY": 0.1217740453149801, "EMPAGLIFLOZIN": 42.3645271281246, "IBRANCE": 2.8125735884810448, "JANUMET": 5.41981269751076, "JANUVIA": 5.524205912729828, "PANTOPRAZOLE": 36.44580727454061, "SUTENT": 1.818473849071912, "TOZINAMERAN": 0.9670196863667117, "null": 1.0719577184919225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12716.json
new file mode 100644
index 00000000000..8988fac36da
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12716.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.5135974256182089, "AIMOVIG": 1.8280789586006037, "APREPITANT": 48.45176838222381, "ARANESP": 3.0363889318409263, "BUPRENORPHINE": 6.25179959335758, "COMIRNATY": 0.1613286171685462, "COSENTYX": 1.3858717749573315, "ESOMEPRAZOLE": 11.92598700138102, "GARDASIL": 2.192588415701701, "IBRANCE": 1.6366843692280435, "LYRICA": 3.3795395163595043, "PANTOPRAZOLE": 14.737674844347636, "SPIKEVAX": 0.1785543343195416, "STELARA": 1.4001749493262483, "SUTENT": 0.5611330648323052, "TOZINAMERAN": 0.2848386280866117, "VAXZEVRIA": 0.162173488309216, "ZOSTAVAX": 10.578741594274875, "null": 1.367266634218659}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12717.json
new file mode 100644
index 00000000000..d34be3791df
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12717.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 52.62524406849989, "COMIRNATY": 0.1984523298517737, "null": 0.8608963200868106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12718.json
new file mode 100644
index 00000000000..614dc1e209d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12718.json
@@ -0,0 +1 @@
+{"INTELENCE": 853.9363846056168, "MIRABEGRON": 1151.6607132013544, "null": 0.407070785761184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12719.json
new file mode 100644
index 00000000000..7ebdd4b7e74
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12719.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4759425387749666, "null": 2.396017257465121}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1272.json
index 998f330a8e2..732cd5289cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1272.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1272.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 19.029211966542384, "FENTANYL": 8.470038123728326, "LYRICA": 16.527429711624404, "null": 1.8928068083457328}
\ No newline at end of file
+{"ABILIFY": 2.119468220105331, "ARIPIPRAZOLE": 3.27342448400922, "ATRIPLA": 0.0687560934825448, "AVAMYS": 1.422506813522614, "BRIVARACETAM": 31.83180048056962, "BRIVIACT": 28.10895719829128, "BUDESONIDE": 0.7320203670978617, "BUPRENORPHINE": 1.8839255507156143, "CANNABIDIOL": 115.3863953710028, "CHAMPIX": 3.3111966839362625, "CIMZIA": 0.2482606911881047, "CLOPIDOGREL": 2.397348722444161, "COMIRNATY": 0.0550752011925734, "COMTAN": 7.093137508086747, "CYMBALTA": 0.741409004839854, "DEXAMETHASONE": 0.4652647778093011, "EBIXA": 21.011946629007557, "ENTACAPONE": 7.937667586832355, "FENTANYL": 0.5292670286148529, "FYCOMPA": 12.374557642448412, "GARDASIL": 0.7305117774873121, "HUMIRA": 1.044159726545695, "KAFTRIO": 17.594364430795448, "KALETRA": 2.56335773884294, "KEPPRA": 17.137727840557282, "LACOSAMIDE": 8.239082236076753, "LEVETIRACETAM": 24.082626939401504, "LEVODOPA": 5.929558998271033, "LYRICA": 2.402661176498017, "MELATONIN": 4.078974386039061, "MMRVAXPRO": 1.94561241591405, "OLANZAPINE": 3.745993646550259, "PEGASYS": 0.1751687343473988, "PREGABALIN": 3.812427789585103, "SIFROL": 16.669319252473922, "SPIKEVAX": 0.0248972031915645, "STALEVO": 3.3670274828395783, "SUBOXONE": 2.2192745103184963, "TAMIFLU": 1.828745564500908, "VFEND": 0.894662217875838, "VIMPAT": 3.726300388674943, "ZYPREXA": 2.513334593176341, "null": 2.8001239179069044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12720.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12720.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12721.json
new file mode 100644
index 00000000000..61d7ed8d20e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12721.json
@@ -0,0 +1 @@
+{"ORENCIA": 2757.3964565651327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12722.json
new file mode 100644
index 00000000000..7e1ee64e7a5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12722.json
@@ -0,0 +1 @@
+{"null": 0.5851496898119035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12723.json
new file mode 100644
index 00000000000..2eb8cff44eb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12723.json
@@ -0,0 +1 @@
+{"null": 0.3568059494881493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12724.json
new file mode 100644
index 00000000000..fab4c423ac5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12724.json
@@ -0,0 +1 @@
+{"ACLASTA": 53.85487049570725, "AMBRISENTAN": 24.229767969928343, "ANAKINRA": 16.937498624834127, "ARAVA": 0.5408486985392564, "ATRIPLA": 2.8760969327266577, "AUBAGIO": 2.4669298827706894, "CARIPRAZINE": 125.5708508860112, "CELECOXIB": 8.096134432081547, "CIMZIA": 0.9225593893812004, "COMIRNATY": 0.230759300253316, "CYMBALTA": 2.991823653517097, "ELIQUIS": 1.423969544210786, "FORSTEO": 9.45027254818665, "GARDASIL": 2.600567244642193, "HUMIRA": 2.6120762560696664, "IBRANCE": 1.7261253956694145, "KEPPRA": 1.3981301966859612, "LANTUS": 1.0381675401991446, "LYRICA": 3.011550896119146, "ORENCIA": 49.59384394284945, "PEGASYS": 1.0507416564531409, "RINVOQ": 4.008090052715969, "SPIKEVAX": 0.0746402615373188, "STRIBILD": 5.153770237075881, "SUTENT": 1.356855511810798, "TOZINAMERAN": 0.3562462097610303, "TRUVADA": 1.0916605772820815, "VAXZEVRIA": 0.0515902266506543, "XELJANZ": 3.324769462481888, "ZOSTAVAX": 3.741756763415768, "null": 1.1512999302861793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12725.json
new file mode 100644
index 00000000000..918824e0b4c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12725.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.2707924596592481, "ARAVA": 0.1466925151668301, "ATRIPLA": 52.40797324636521, "AUBAGIO": 0.7886603669923565, "BIKTARVY": 1.985791340321757, "BUPRENORPHINE": 1.0802777042075695, "CIMZIA": 0.3859563589736678, "COMIRNATY": 0.1062631842305964, "COSENTYX": 0.5854054912136714, "CYMBALTA": 0.2866797513390129, "ELIQUIS": 0.1610376560668638, "ENBREL": 1.8687161025750791, "ENTYVIO": 0.9561508098014284, "EPADERM": 131.92898654040428, "FAMPYRA": 5.135520900775227, "FORSTEO": 1.2164865533776144, "GARDASIL": 1.3047421717118692, "HUMALOG": 1.5761608047952742, "IBRANCE": 0.4148700766597462, "JANUMET": 1.3376909714447611, "KEPPRA": 0.7184032092417111, "LANTUS": 0.1834176525757021, "LYRICA": 1.2079820550658862, "METFORMIN": 12.499801468984623, "OLANZAPINE": 0.5135458891518075, "SPIKEVAX": 0.0844897822442697, "STELARA": 0.4841082072295887, "STRIBILD": 14.623116481880254, "SUTENT": 0.1365020176329434, "TASIGNA": 0.8903939312860387, "TOZINAMERAN": 0.1568293479864313, "TRUVADA": 16.546395533804326, "VAXZEVRIA": 0.0601421580719483, "VIREAD": 5.256331873717271, "XOLAIR": 0.340871365116959, "ZOSTAVAX": 10.433134588544378, "null": 0.2753514136621085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12726.json
new file mode 100644
index 00000000000..0241c15db3c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12726.json
@@ -0,0 +1 @@
+{"FORSTEO": 20.14436392433228, "null": 1.2312115710661506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12727.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12727.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12728.json
new file mode 100644
index 00000000000..2fdcdf23f18
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12728.json
@@ -0,0 +1 @@
+{"null": 2.4656473380232584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12729.json
new file mode 100644
index 00000000000..6377c96f552
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12729.json
@@ -0,0 +1 @@
+{"null": 6.941429057685932}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1273.json
index 274bdb4695b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1273.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1273.json
@@ -1 +1 @@
-{"ABACAVIR": 8.032117069749779, "ENBREL": 9.447609357133034}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12730.json
new file mode 100644
index 00000000000..5d4320a5965
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12730.json
@@ -0,0 +1 @@
+{"null": 2.2487134487667064}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12731.json
new file mode 100644
index 00000000000..ff4a40af3ef
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12731.json
@@ -0,0 +1 @@
+{"ALDARA": 31.379429357719623, "AZATHIOPRINE": 3.606048391896061, "BRAFTOVI": 5.381217776298687, "CICLOSPORIN": 1.8342207823142067, "COMIRNATY": 0.6829240185395336, "COSENTYX": 4.256212089187321, "ETANERCEPT": 46.02879122375792, "IPILIMUMAB": 112.66543173819584, "KEYTRUDA": 19.697940508085768, "KISQALI": 35.761569876368, "LEMTRADA": 11.135971197267155, "MEKINIST": 5.291010753912912, "NEOFORDEX": 830.8278739549502, "OPDIVO": 11.99276302293395, "PEGASYS": 1.5756351722208046, "PEMBROLIZUMAB": 44.42319349079082, "RIBOCICLIB": 31.45282931179806, "SPIKEVAX": 0.5247566772368607, "STELARA": 7.570687223201722, "TOZINAMERAN": 0.5965338934555959, "VAXZEVRIA": 0.4352082654388898, "XOLAIR": 1.6312759102483432, "YERVOY": 30.315521759509934, "null": 0.2603155538700739}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12732.json
new file mode 100644
index 00000000000..fdd6b75dfff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12732.json
@@ -0,0 +1 @@
+{"BEOVU": 1187.2914145958564, "EYLEA": 605.7148111016025, "null": 0.4353932050625643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12733.json
new file mode 100644
index 00000000000..50b47f72fe3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12733.json
@@ -0,0 +1 @@
+{"EYLEA": 2302.14169630413, "null": 0.1295522879685686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12734.json
new file mode 100644
index 00000000000..1c4978a62dd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12734.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": 68.89869898521313, "null": 0.3355058085531069}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12735.json
new file mode 100644
index 00000000000..ecd544631e5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12735.json
@@ -0,0 +1 @@
+{"AVASTIN": 6.326911472866099, "BEOVU": 48.30570463289322, "COMIRNATY": 1.452636005806422, "EYLEA": 28.304706740628085, "PEGASYS": 1.017047569885857, "SPIKEVAX": 0.6403384516549598, "STELARA": 1.5365825784899556, "TOZINAMERAN": 1.7549856552736107, "VAXZEVRIA": 1.296204259128086, "VIAGRA": 9.086964720024444, "VOTRIENT": 3.008657789062193, "ZOSTAVAX": 17.277323232375014, "null": 0.5228520229301269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12736.json
new file mode 100644
index 00000000000..495f950c90d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12736.json
@@ -0,0 +1 @@
+{"BEOVU": 202.60103771510336, "COMIRNATY": 0.4171169894162769, "EYLEA": 187.13640036231493, "LANTUS": 4.320797211953483, "null": 0.7299193778440103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12737.json
new file mode 100644
index 00000000000..4702f722f77
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12737.json
@@ -0,0 +1 @@
+{"AFLIBERCEPT": 26.678009385094903, "AVASTIN": 4.041762779810134, "BEOVU": 461.0423291570274, "BRAFTOVI": 3.8117590166578816, "BROLUCIZUMAB": 392.4118346221145, "BYETTA": 1.0363880976254904, "COMIRNATY": 0.4731040352063904, "ENTRESTO": 0.7393239629314725, "EYLEA": 98.647890454117, "GARDASIL": 0.5554402682404301, "HUMALOG": 1.7119366789426225, "JETREA": 214.3381931016016, "LANTUS": 0.8848367592787162, "LEVOFLOXACIN": 1.2314203552813294, "LUCENTIS": 50.7839591065242, "MEKINIST": 3.788368993071226, "NEVANAC": 13.201610583454848, "PEGASYS": 1.474362974773943, "PEGINTRON": 1.2240404465923505, "PLAVIX": 1.0089118075846495, "SPIKEVAX": 0.387844300439563, "STELARA": 0.5830217928660171, "TOZINAMERAN": 1.740881706691756, "VAXZEVRIA": 0.7971046651982898, "VFEND": 2.7677161556824275, "VIAGRA": 4.407535120403818, "VORICONAZOLE": 4.663987563718454, "VOTRIENT": 1.1415714105714072, "XALKORI": 6.663853560790042, "XELJANZ": 0.4147350254184972, "XTANDI": 0.7788523697018648, "ZOSTAVAX": 3.266554741232844, "null": 0.7581870861112321}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12738.json
new file mode 100644
index 00000000000..af0df1cc0c6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12738.json
@@ -0,0 +1 @@
+{"BEOVU": 33.94671956050921, "CELSENTRI": 76.49031122004548, "CLOPIDOGREL": 4.168611292573515, "COMIRNATY": 0.5327429963332186, "ELIQUIS": 5.615855405127405, "EYLEA": 104.26899731433686, "HUMALOG": 3.6564716008146103, "LANTUS": 11.539529861265088, "PLAVIX": 4.549600351482042, "RIVAROXABAN": 31.995819740308228, "SPIKEVAX": 0.1660077692902269, "TOPOTECAN": 50.29457033338881, "VAXZEVRIA": 0.1936634748935524, "VIAGRA": 3.433747060083016, "null": 0.5494825544779275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12739.json
new file mode 100644
index 00000000000..d4681e79e60
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12739.json
@@ -0,0 +1 @@
+{"BEOVU": 576.5055252585477, "BROLUCIZUMAB": 131.73476936043124, "COMIRNATY": 0.2320937591886498, "EYLEA": 296.55481735337685, "VAXZEVRIA": 0.0837203006135276, "ZOSTAVAX": 1.6212932375450075, "null": 1.7172322150463528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1274.json
index b3d2aefa84d..0bb00b81150 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1274.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1274.json
@@ -1 +1 @@
-{"null": 1.8216547341603908}
\ No newline at end of file
+{"BUPRENORPHINE": 96.14786459599166, "null": 1.1487346130258136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12740.json
new file mode 100644
index 00000000000..abe9d72e7e8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12740.json
@@ -0,0 +1 @@
+{"AFLIBERCEPT": 64.12126205450458, "AVASTIN": 3.236603692941248, "BEOVU": 1901.024326727793, "BROLUCIZUMAB": 1358.4940564151543, "EYLEA": 341.35935919575303, "null": 0.437976506632946}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12741.json
new file mode 100644
index 00000000000..de33cf8e420
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12741.json
@@ -0,0 +1 @@
+{"null": 1.2678387061803291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12742.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12742.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12743.json
new file mode 100644
index 00000000000..af6a9a0000a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12743.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2862992344864966, "null": 1.6196744006808153}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12744.json
new file mode 100644
index 00000000000..1dc863bc974
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12744.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 289.5288823974089, "COMIRNATY": 0.1384484805079751, "NUCALA": 10.759292845133167, "null": 0.5091254680724344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12745.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12745.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12746.json
new file mode 100644
index 00000000000..1f038a7d592
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12746.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6297370698202258, "null": 1.5728435638234404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12747.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12747.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12748.json
new file mode 100644
index 00000000000..d6846dc1439
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12748.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4458436208515867, "KEYTRUDA": 2.094980583399076, "SPIKEVAX": 0.2244985407742862, "TOZINAMERAN": 0.615284644703376, "VAXZEVRIA": 0.2090476972222923, "null": 1.815058590388584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12749.json
new file mode 100644
index 00000000000..89eb5406534
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12749.json
@@ -0,0 +1 @@
+{"null": 0.6391236183990162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1275.json
index 466fc382d0d..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1275.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1275.json
@@ -1 +1 @@
-{"null": 4.254321323894745}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12750.json
new file mode 100644
index 00000000000..5adb9fbef98
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12750.json
@@ -0,0 +1 @@
+{"null": 1.7353989582426508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12751.json
new file mode 100644
index 00000000000..9e99f4e4f73
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12751.json
@@ -0,0 +1 @@
+{"null": 1.3940275783800191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12752.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12752.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12753.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12753.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12754.json
new file mode 100644
index 00000000000..4b0ab538685
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12754.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3245584789330458, "IPILIMUMAB": 30.65577505972935, "KEYTRUDA": 9.601524784091437, "MEKINIST": 29.866924239522238, "OPDIVO": 39.36864820526257, "PEGASYS": 10.081442698463515, "PEGINTERFERON": 38.49693201227187, "PEGINTRON": 25.70195007680612, "SPIKEVAX": 0.4244308754753337, "TOZINAMERAN": 1.6950780738097473, "null": 0.0956629083158483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12755.json
new file mode 100644
index 00000000000..3ef6b2b6076
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12755.json
@@ -0,0 +1 @@
+{"null": 1.3677424592554597}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12756.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12756.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12757.json
new file mode 100644
index 00000000000..9de2227e6e2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12757.json
@@ -0,0 +1 @@
+{"AIMOVIG": 7.201855047825768, "CLOPIDOGREL": 3.911424881232074, "COMIRNATY": 0.0977582160403223, "ISENTRESS": 119.25554450312762, "KEPPRA": 2.8328051299593837, "SIMPONI": 5.008760430623346, "null": 0.9824913166624638}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12758.json
new file mode 100644
index 00000000000..4d7a1f05877
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12758.json
@@ -0,0 +1 @@
+{"null": 0.6780206922776975}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12759.json
new file mode 100644
index 00000000000..094a84755a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12759.json
@@ -0,0 +1 @@
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0.9929715046376434, "TRABECTEDIN": 0.8580851924845093, "TRACLEER": 0.7492603979070834, "TRACTOCILE": 0.6823591280397578, "TRASTUZUMAB": 0.8811571594064591, "TRELEGY": 0.1975035026438576, "TREMFYA": 0.3461389056134822, "TREPROSTINIL": 1.8569520312568424, "TRESIBA": 0.3673417092607948, "TRIUMEQ": 0.833123565853914, "TRODELVY": 1.6463202765274565, "TRULICITY": 5.505878962868259, "TRUVADA": 0.0574022577597783, "TWINRIX": 1.0639450591528858, "UNSPECIFIED": 0.3261340636628486, "UPADACITINIB": 0.4453998681425277, "USTEKINUMAB": 0.404093486867622, "VALDOXAN": 0.6109315018854915, "VALSARTAN": 0.4187055464766991, "VARENICLINE": 2.055785199959753, "VAXZEVRIA": 1.2583438211182345, "VECTIBIX": 0.4574966343678465, "VEDOLIZUMAB": 0.4805580408847027, "VEKLURY": 0.2462656949443173, "VELCADE": 0.7397480656437219, "VELMETIA": 0.8562836438953374, "VELTASSA": 0.7811567228523486, "VEMLIDY": 0.4465571629924214, "VEMURAFENIB": 0.5628338870908722, "VENCLYXTO": 0.3444007236650967, "VENETOCLAX": 0.4671835998942516, "VERZENIOS": 1.487256232765051, "VFEND": 0.4453246899985527, "VIAGRA": 0.2395850388802728, "VICTOZA": 4.003894986364196, "VIGABATRIN": 0.3492556112868939, "VILDAGLIPTIN": 1.0853327251583074, "VIMPAT": 1.193293641392348, "VIRAMUNE": 1.521688056064027, "VIREAD": 0.3817364721659634, "VORICONAZOLE": 0.3790100697185034, "VORTIOXETINE": 1.4795383197932288, "VOTRIENT": 1.6992841735455495, "XALKORI": 2.2026802906884155, "XARELTO": 0.4361497187881172, "XELJANZ": 0.4367508853404605, "XELODA": 2.914426484594333, "XOFIGO": 0.7053260800596922, "XOLAIR": 0.5728665644287267, "XTANDI": 0.7950032148239286, "XYREM": 0.8304209440405632, "YERVOY": 0.5454998541252659, "YESCARTA": 0.1977729961787375, "YONDELIS": 1.4749328285025018, "ZALTRAP": 1.5808229464078023, "ZARZIO": 0.9587525264530422, "ZAVESCA": 0.6522317301232814, "ZEJULA": 0.6951988073101895, "ZELBORAF": 1.1019664748885014, "ZEPATIER": 1.4399805577870362, "ZERIT": 1.0473610998642795, "ZIAGEN": 2.6955103850639395, "ZOLEDRONIC": 1.0366217900639942, "ZOMETA": 0.2443035100519115, "ZONISAMIDE": 0.3669026435529278, "ZOSTAVAX": 0.2594087144947793, "ZYPADHERA": 0.2923438655881333, "ZYPREXA": 0.5024606576140896, "null": 1.288432661753942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1276.json
index 3033db1bc8b..995c963ad0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1276.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1276.json
@@ -1 +1 @@
-{"ABRAXANE": 12.773341168622522, "AFINITOR": 7.69211205303828, "ALPELISIB": 18.173663496496665, "ANORO": 1.312319819130824, "AUBAGIO": 1.7777260371377912, "AVONEX": 3.217422058519721, "BETAFERON": 2.9509869245289586, "BYETTA": 1.1648493769828956, "CAELYX": 1.979701308528912, "CAPECITABINE": 6.423818021981213, "CARMUSTINE": 1.4921069543515024, "CIMZIA": 1.2208361252568454, "COSENTYX": 1.428510313979681, "DENOSUMAB": 5.430666060399886, "DOCETAXEL": 2.2618099766331747, "ERIBULIN": 7.494784919849463, "ESMYA": 2.2236743958010665, "EVENITY": 1.513716623047395, "EVEROLIMUS": 3.393652508877239, "EVISTA": 13.40162752097214, "FASENRA": 1.0022333303014244, "FASLODEX": 4.948846560443956, "FORSTEO": 1.9053631546015424, "FULVESTRANT": 12.554780723963908, "HERCEPTIN": 1.8988854533118256, "HUMALOG": 1.390712729928513, "KESIMPTA": 2.3297094260879407, "KISQALI": 12.82799912393435, "LANTUS": 1.7357287567867592, "LEVEMIR": 1.4676648401576984, "LYNPARZA": 1.1446486652883556, "MAVENCLAD": 2.1640453128530317, "NEULASTA": 1.4331176095550415, "OMALIZUMAB": 1.9294714759466516, "ONGLYZA": 1.231812897140457, "PACLITAXEL": 3.0103247338890853, "PIQRAY": 5.626746484333479, "RIBOCICLIB": 11.848224408275744, "RINVOQ": 1.1292666756547614, "ROACTEMRA": 2.355476740324448, "SAXENDA": 1.910917562543603, "SIMPONI": 2.466156238789519, "SKYRIZI": 2.2396290525552947, "STELARA": 4.344058011181831, "TAXOTERE": 2.3841679570405825, "TESTOSTERONE": 3.90925065961056, "TRELEGY": 1.800582449769988, "TREMFYA": 3.5062825348249373, "VICTOZA": 1.5416159706503156, "XELJANZ": 1.2200023027182991, "XOLAIR": 3.7785167452857, "null": 5.389194160530513}
\ No newline at end of file
+{"ADALIMUMAB": 1.442033888465306, "CICLOSPORIN": 34.624434305527856, "COMIRNATY": 0.5789607042033172, "COSENTYX": 5.470506667279473, "TOZINAMERAN": 1.4084372137870496, "VAXZEVRIA": 0.1777094306017701, "null": 0.666366429559404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12760.json
new file mode 100644
index 00000000000..0072379982f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12760.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5040106907599978, "INFANRIX": 15.627793947683672, "MMRVAXPRO": 3.1169022698731026, "ROTATEQ": 40.69756006526693, "SPIKEVAX": 0.5636274698262572, "SUBOXONE": 5.692177140957735, "TOZINAMERAN": 2.367964390180853, "TRULICITY": 11.763332078493436, "VAXZEVRIA": 1.6925847298589851, "null": 1.043948373145639}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12761.json
new file mode 100644
index 00000000000..7f8e993fba9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12761.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4835129563572765, "null": 1.403982565750079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12762.json
new file mode 100644
index 00000000000..0e3f2a5bc2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12762.json
@@ -0,0 +1 @@
+{"null": 1.0567857957019913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12763.json
new file mode 100644
index 00000000000..16421ded631
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12763.json
@@ -0,0 +1 @@
+{"CINRYZE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12764.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12764.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12765.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12765.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12766.json
new file mode 100644
index 00000000000..87e9ea6aff7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12766.json
@@ -0,0 +1 @@
+{"null": 7.0374394613113145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12767.json
new file mode 100644
index 00000000000..1b35c45de0b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12767.json
@@ -0,0 +1 @@
+{"null": 14.064242059286538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12768.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12768.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12769.json
new file mode 100644
index 00000000000..056e5b4282b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12769.json
@@ -0,0 +1 @@
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1277.json
index 0e5a7a7a989..0b5b410527e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1277.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1277.json
@@ -1 +1 @@
-{"AFINITOR": 4.0395693042904295, "AUBAGIO": 3.651024346219854, "BYDUREON": 6.364684333324517, "DOCETAXEL": 3.406063262185252, "ENBREL": 1.4598044796306489, "ENTYVIO": 2.0726610378330133, "FASENRA": 7.11922868458, "FASLODEX": 16.866753453846005, "FORXIGA": 2.6563092224026814, "IBRANCE": 1.0683675328189723, "JARDIANCE": 1.3353687887503132, "LANTUS": 1.333742195641997, "PLEGRIDY": 8.178714821144325, "RINVOQ": 11.749656230069142, "SKYRIZI": 20.32500959336669, "XELJANZ": 7.836133796873424, "ZOSTAVAX": 1.0298413806492823, "null": 3.612261894267164}
\ No newline at end of file
+{"APIXABAN": 0.3741729290453578, "ATRIPLA": 0.0547694416937599, "AVANDIA": 0.4319626086040374, "BYDUREON": 1.5586899601342976, "CIMZIA": 0.1953933416237139, "COMIRNATY": 2.770329639672858, "COSENTYX": 0.2963651754515385, "ELIQUIS": 0.2037169695898904, "FORXIGA": 1.0169395283820668, "GARDASIL": 0.9716485814323826, "HUMALOG": 0.2633180573110009, "JANUMET": 0.4376055864625164, "LANTUS": 0.2320283954817022, "PEGASYS": 1.4218323528373993, "PEGINTERFERON": 1.02810256266582, "PEGINTRON": 1.6339200681476034, "RIBAVIRIN": 0.9539191221271694, "SHINGRIX": 6.533700957413349, "SIMPONI": 0.2620564239454183, "SPIKEVAX": 2.7323480043214343, "STELARA": 1.6124415163256836, "TASIGNA": 0.6252637916968765, "TOZINAMERAN": 9.484947979037566, "VAXZEVRIA": 1.4456146413709436, "VICTOZA": 0.769285691505448, "XELJANZ": 0.210367465602266, "XOLAIR": 0.8424558908104233, "ZOSTAVAX": 7.838468840533993, "null": 0.1454789523763425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12770.json
new file mode 100644
index 00000000000..0d660462fec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12770.json
@@ -0,0 +1 @@
+{"JARDIANCE": 56.097458116975766, "null": 0.2215602444760471}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12771.json
new file mode 100644
index 00000000000..4666bb600d9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12771.json
@@ -0,0 +1 @@
+{"null": 1.1550023484127947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12772.json
new file mode 100644
index 00000000000..1d2d368d556
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12772.json
@@ -0,0 +1 @@
+{"LYRICA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12773.json
new file mode 100644
index 00000000000..731a739207a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12773.json
@@ -0,0 +1 @@
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12774.json
new file mode 100644
index 00000000000..8651cc2a8ce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12774.json
@@ -0,0 +1 @@
+{"OLANZAPINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12775.json
new file mode 100644
index 00000000000..11e3a68a6ec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12775.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 2.6975095142422063, "CELLCEPT": 16.47010575486855, "COMIRNATY": 0.3049710107198134, "null": 0.9019616483171792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12776.json
new file mode 100644
index 00000000000..b2ce4d84d16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12776.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.560940441669412, "TOZINAMERAN": 10.077232026151933, "VAXZEVRIA": 2.6888684076896694, "null": 0.3079196916179644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12777.json
new file mode 100644
index 00000000000..609d3724609
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12777.json
@@ -0,0 +1 @@
+{"null": 2.5255031756221853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12778.json
new file mode 100644
index 00000000000..6f2f7730f69
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12778.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8718728598751759, "SPIKEVAX": 0.4489072535289463, "TOZINAMERAN": 3.7062297903944574, "VAXZEVRIA": 0.7273391964561263, "null": 0.8266162135174624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12779.json
new file mode 100644
index 00000000000..40991961779
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12779.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1278.json
index 5b9b0cf84e4..9892890e198 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1278.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1278.json
@@ -1 +1 @@
-{"null": 2.5201459396265244}
\ No newline at end of file
+{"null": 2.08806022860263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12780.json
new file mode 100644
index 00000000000..88a22b245c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12780.json
@@ -0,0 +1 @@
+{"null": 1.8228240307521328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12781.json
new file mode 100644
index 00000000000..11dc701869f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12781.json
@@ -0,0 +1 @@
+{"FORXIGA": 60.71383697154238, "JARDIANCE": 40.03045915964419, "null": 0.6655904705228368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12782.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12782.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12783.json
new file mode 100644
index 00000000000..1c424d9a8b1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12783.json
@@ -0,0 +1 @@
+{"ALDARA": 33.75958637737784, "COMIRNATY": 0.2657295580120951, "FORXIGA": 10.379159076147577, "ISENTRESS": 16.980888411750303, "JARDIANCE": 15.011809303702227, "PEGASYS": 1.1767809262167948, "SPIKEVAX": 0.1349351804715432, "TOZINAMERAN": 0.3335696486636296, "VAXZEVRIA": 0.1025400695613844, "null": 4.540675368759277}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12784.json
new file mode 100644
index 00000000000..d0165c94879
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12784.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4179513063394845, "COSENTYX": 9.736597588498617, "EMPAGLIFLOZIN": 81.26775543369882, "FORXIGA": 37.94008651385791, "JARDIANCE": 32.12770103574482, "KARVEA": 155.6799966179927, "NUCALA": 2.583251620723296, "SIMPONI": 1.88989036388184, "SPIKEVAX": 0.2585699591754856, "STELARA": 1.7047297038476945, "SUBOXONE": 2.4830436304019723, "TOZINAMERAN": 0.9788185326117328, "VAXZEVRIA": 0.3175577745498361, "null": 1.067443916276045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12785.json
new file mode 100644
index 00000000000..72353bd1f5b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12785.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3982097194776633, "EMPAGLIFLOZIN": 29.0323505464779, "FORXIGA": 8.951765374410034, "JARDIANCE": 9.262553501584645, "SPIKEVAX": 0.2562059895426002, "VAXZEVRIA": 0.1384101875121008, "null": 3.705270555564885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12786.json
new file mode 100644
index 00000000000..4928eb69645
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12786.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5054271021091592, "FASLODEX": 11.455074088722212, "FORXIGA": 6.230682763262948, "IBRANCE": 2.7275776224284645, "JARDIANCE": 5.677823032157448, "VAXZEVRIA": 0.2062735604229295, "null": 2.7145830681762453}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12787.json
new file mode 100644
index 00000000000..547860aa0e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12787.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1721990752338008, "JARDIANCE": 15.986893820931272, "null": 3.9494490991577256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12788.json
new file mode 100644
index 00000000000..c672f926dcd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12788.json
@@ -0,0 +1 @@
+{"null": 10.082002914584136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12789.json
new file mode 100644
index 00000000000..39076746a5a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12789.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2493313780327817, "FORXIGA": 17.614229007768127, "JARDIANCE": 7.05586513463335, "null": 1.7195883235281324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1279.json
index 2ff977a53d5..28c9315c5fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1279.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1279.json
@@ -1 +1 @@
-{"null": 5.793712599498985}
\ No newline at end of file
+{"CLOPIDOGREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12790.json
new file mode 100644
index 00000000000..62dfc93c3a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12790.json
@@ -0,0 +1 @@
+{"null": 4.901861877610053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12791.json
new file mode 100644
index 00000000000..b02348398f7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12791.json
@@ -0,0 +1 @@
+{"CIMZIA": 1.319090870983229, "COMIRNATY": 0.886844393832853, "COSENTYX": 4.144883740793408, "DEXAMETHASONE": 1.734856255536115, "FENTANYL": 1.743462512677698, "FORXIGA": 46.60536060093054, "INVOKANA": 25.288627745971905, "JARDIANCE": 74.67564156750996, "PEGASYS": 0.7864020225511258, "RINVOQ": 3.135168175014865, "SPIKEVAX": 0.3335945842657075, "STELARA": 2.0665734640888545, "VAXZEVRIA": 0.0737641927242205, "null": 1.1301491706710365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12792.json
new file mode 100644
index 00000000000..9ffa9eda409
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12792.json
@@ -0,0 +1 @@
+{"CAPECITABINE": 7.680951953905511, "COMIRNATY": 1.079988904527309, "FORXIGA": 4.738020579030365, "JARDIANCE": 6.119157749922886, "SPIKEVAX": 0.5561636788576784, "TOZINAMERAN": 1.3952054597922552, "VAXZEVRIA": 0.3844117407979646, "null": 2.057132605241773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12793.json
new file mode 100644
index 00000000000..ababb2cdc8b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12793.json
@@ -0,0 +1 @@
+{"BETMIGA": 22.8773739055385, "COMIRNATY": 0.2435258641531353, "ELIQUIS": 0.7742468356299385, "ELLAONE": 22.795403911648453, "EMPAGLIFLOZIN": 38.23713240228954, "FORXIGA": 43.92037757777416, "IBRANCE": 1.2386705455171618, "JARDIANCE": 51.77856752872944, "PEGASYS": 0.835729937088126, "SPIKEVAX": 0.1246848068639736, "VAXZEVRIA": 0.0861802524610091, "null": 2.216348149460394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12794.json
new file mode 100644
index 00000000000..cd6ef494cf1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12794.json
@@ -0,0 +1 @@
+{"null": 2.8906501955780493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12795.json
new file mode 100644
index 00000000000..4b7b6337768
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12795.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.395654056297664, "JARDIANCE": 21.935271692573156, "SPIKEVAX": 0.3359240305330691, "TOZINAMERAN": 0.9206686307064976, "null": 2.536278637662946}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12796.json
new file mode 100644
index 00000000000..a3f8b20bfc1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12796.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 1.9535802139771763, "null": 0.7826078445688444}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12797.json
new file mode 100644
index 00000000000..da561c9d264
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12797.json
@@ -0,0 +1 @@
+{"EMPAGLIFLOZIN": 60.44133240945552, "FORXIGA": 186.9292182340031, "JARDIANCE": 130.65134650861395, "null": 0.2934578986045321}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12798.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12798.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12799.json
new file mode 100644
index 00000000000..63a755acd72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12799.json
@@ -0,0 +1 @@
+{"RITUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/128.json
index b1076ba859d..b14358a82dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/128.json
@@ -1 +1 @@
-{"ACTOS": 8.913034987531725, "AERIUS": 5.787070142423634, "ALIMTA": 2.690328480427259, "AMIKACIN": 5.658988385009125, "ARIXTRA": 13.558215731959434, "BRIDION": 3.699357446072573, "CANCIDAS": 10.534539441437744, "CASPOFUNGIN": 17.754355552551747, "CUBICIN": 5.903141674212228, "DEXAMETHASONE": 2.7241377160235625, "DIFICLIR": 21.42782478114413, "ENOXAPARIN": 2.6247533865860007, "IBUPROFEN": 5.515148025482381, "INCIVO": 2.700346096947215, "JANUVIA": 1.2547663233873698, "KEPPRA": 1.7344184634656237, "LEVETIRACETAM": 2.915635530766832, "LEVOFLOXACIN": 3.1864692528153307, "MICARDIS": 1.8288376295144229, "MIDAZOLAM": 4.007620142677752, "PANTOPRAZOLE": 5.211711439464579, "PLAVIX": 1.0371068670078871, "SPIRONOLACTONE": 11.07671652950718, "SUFENTANIL": 7.403251602720803, "TAMIFLU": 1.2242193151779783, "null": 6.349263987112983}
\ No newline at end of file
+{"AMINOSALICYLIC": 1.5629875450751076, "AVANDIA": 0.6333565735454696, "BUPRENORPHINE": 1.477489823192988, "CANCIDAS": 5.918102830647242, "CELLCEPT": 1.5530879990120163, "CICLOSPORIN": 1.117295563402709, "COAPROVEL": 4.431814878563364, "COMIRNATY": 0.0408469386308413, "CRIXIVAN": 13.537338732351133, "CYMBALTA": 0.5095690024338325, "DEXAMETHASONE": 0.7399079977602787, "DULOXETINE": 2.797280430272345, "EMPAGLIFLOZIN": 7.003727962019444, "EXJADE": 2.1980557711728936, "FENTANYL": 1.5974767513575672, "FORXIGA": 4.94348161498165, "HUMALOG": 0.5420895481686365, "IBUPROFEN": 7.246006245476541, "IRBESARTAN": 3.19258373693702, "JANUMET": 1.5261071993362962, "JANUVIA": 1.6227120585115722, "JARDIANCE": 11.577659973163684, "KEPPRA": 1.342644625817972, "KEYTRUDA": 0.4443514234767319, "LACOSAMIDE": 3.792393558189127, "LAMIVUDINE": 4.607419543616195, "LANTUS": 0.6077405657962592, "LEVETIRACETAM": 0.963567209964534, "MICARDIS": 1.9256302045775189, "MIDAZOLAM": 3.49102154682332, "NOVONORM": 8.83169939629433, "NOVORAPID": 1.8672911141254136, "OLANZAPINE": 1.1641486121501676, "PEGASYS": 0.6279117566654312, "PLAVIX": 0.6430888583573261, "ROTATEQ": 3.917466984994348, "SPIKEVAX": 0.0357468910481004, "SUTENT": 0.3303157102625005, "TRUVADA": 0.4358091207613465, "VAXZEVRIA": 0.019496944273292, "ZYPREXA": 2.216967025830745, "null": 2.836196010116036}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1280.json
index 0d3f7ef5407..48f1b266ee5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1280.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1280.json
@@ -1 +1 @@
-{"ABEMACICLIB": 93.15999432842683, "ABRAXANE": 138.3994817997619, "AFINITOR": 30.027715219178152, "ALPELISIB": 78.26872288510475, "AVASTIN": 2.0348898292989803, "BEVACIZUMAB": 2.2729636564145133, "CAELYX": 13.844215625537611, "CAPECITABINE": 33.63844507578386, "DENOSUMAB": 17.192373717274624, "DOCETAXEL": 14.60093476357107, "DOXORUBICIN": 1.8599273450109064, "ERIBULIN": 56.213053812705134, "EVEROLIMUS": 39.16397170009321, "EVISTA": 3.136122849503648, "FASLODEX": 27.585140602878425, "FULVESTRANT": 111.6333709849885, "HERCEPTIN": 10.083868526044066, "IBRANCE": 6.342310156859161, "KISQALI": 49.261672259770044, "NEULASTA": 1.71977207197164, "PACLITAXEL": 4.32039000032839, "PIQRAY": 43.98467014680431, "RIBOCICLIB": 106.076078243657, "TESTOSTERONE": 8.942166329506405, "TRODELVY": 4.112835023218993, "null": 2.017743264265305}
\ No newline at end of file
+{"METHOTREXATE": 165.8535008077542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12800.json
new file mode 100644
index 00000000000..8f60ef5484b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12800.json
@@ -0,0 +1 @@
+{"LUVERIS": 1068.125355537261, "null": 1.36704737227687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12801.json
new file mode 100644
index 00000000000..4917481274c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12801.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2897616542499877, "null": 0.5512368642797312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12802.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12802.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12803.json
new file mode 100644
index 00000000000..d56f31774b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12803.json
@@ -0,0 +1 @@
+{"ABATACEPT": 6.150198795536324, "ATRIPLA": 1.1596021615719172, "AUBAGIO": 28.59446487593257, "BELIMUMAB": 127.29738705648506, "BENLYSTA": 5.213523591683449, "CIMZIA": 1.3136807107900994, "COMIRNATY": 0.2415509864331651, "ENBREL": 6.167754469016563, "ESBRIET": 7.900113911840121, "FIRDAPSE": 10.844775682483965, "GARDASIL": 1.2545123277421324, "HUMALOG": 1.172295715722227, "KEPPRA": 1.293110244175188, "LANTUS": 7.077326338202556, "SHINGRIX": 2.541342339980898, "SPIKEVAX": 0.954319612485094, "STRIBILD": 4.229195771901956, "TOZINAMERAN": 0.4697507246332801, "TRUVADA": 1.091558910257506, "VAXZEVRIA": 0.0591996304062064, "XELJANZ": 2.8852050200543924, "XTANDI": 2.140420282989459, "null": 0.8628343609021795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12804.json
new file mode 100644
index 00000000000..87ccda625d9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12804.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8348754635193031, "GARDASIL": 2.061062885187697, "KALETRA": 6.187140152641053, "KEPPRA": 2.00847525755037, "LANTUS": 1.991641204742664, "SPIKEVAX": 0.3139342140978404, "SUTENT": 2.178228094310436, "TOZINAMERAN": 1.720345811974361, "VAXZEVRIA": 0.3328605015398255, "XELJANZ": 1.7702939381151024, "XTANDI": 2.150272596352453, "null": 1.3815686036833172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12805.json
new file mode 100644
index 00000000000..314e55022cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12805.json
@@ -0,0 +1 @@
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12806.json
new file mode 100644
index 00000000000..8d26fa3ff2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12806.json
@@ -0,0 +1 @@
+{"ESBRIET": 52.4690334259277, "OPSUMIT": 85.65182090258286, "TRACLEER": 68.62983098871018, "null": 0.1667354833749596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12807.json
new file mode 100644
index 00000000000..6ed6d3e8c0b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12807.json
@@ -0,0 +1 @@
+{"OPSUMIT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12808.json
new file mode 100644
index 00000000000..2d4e7966a53
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12808.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6073878284882761, "KEYTRUDA": 14.567172774168831, "null": 0.6005349428842733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12809.json
new file mode 100644
index 00000000000..143fe7f4aad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12809.json
@@ -0,0 +1 @@
+{"VEMURAFENIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1281.json
index f3bf65aa07b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1281.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1281.json
@@ -1 +1 @@
-{"AFINITOR": 45.78169764025509, "CAPECITABINE": 27.46717806307184, "DENOSUMAB": 32.63378619914449, "DOCETAXEL": 22.72779337959479, "EVISTA": 18.46245009646464, "FASLODEX": 94.15095590242464, "FORSTEO": 1.8634678795047557, "FULVESTRANT": 53.30427663977488, "HERCEPTIN": 30.195068805959075, "IBRANCE": 3.8238023274635182, "KISQALI": 21.115083688579197, "NEULASTA": 8.554132483182011, "PACLITAXEL": 20.96213965481388, "RIBOCICLIB": 24.06288820845183}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12810.json
new file mode 100644
index 00000000000..f5b26aaedbb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12810.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 12.225312067202616, "SYCREST": 158.27905800056652, "ZYPREXA": 22.635089173349705, "null": 4.780047389067644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12811.json
new file mode 100644
index 00000000000..425edd19760
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12811.json
@@ -0,0 +1 @@
+{"null": 0.9518920967503458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12812.json
new file mode 100644
index 00000000000..8226be2aa8b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12812.json
@@ -0,0 +1 @@
+{"null": 2.3327811053074563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12813.json
new file mode 100644
index 00000000000..8096d661679
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12813.json
@@ -0,0 +1 @@
+{"CHAMPIX": 23.47599802790567, "null": 1.7942401565018318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12814.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12814.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12815.json
new file mode 100644
index 00000000000..3da59600997
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12815.json
@@ -0,0 +1 @@
+{"VORICONAZOLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12816.json
new file mode 100644
index 00000000000..dc804e9b7e5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12816.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 15.91470130597586, "CLOPIDOGREL": 4.878152027819659, "ELIQUIS": 3.8662522944050304, "HUMALOG": 4.975718342053632, "ZOSTAVAX": 9.44702823520553, "null": 0.975990630772857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12817.json
new file mode 100644
index 00000000000..9be42ff3ebc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12817.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12818.json
new file mode 100644
index 00000000000..528b9feee74
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12818.json
@@ -0,0 +1 @@
+{"SUBOXONE": 72.53584469045063, "null": 2.08806022860263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12819.json
new file mode 100644
index 00000000000..c4b8a97069e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12819.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1282.json
index 0e03ba7a651..078231be7a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1282.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1282.json
@@ -1 +1 @@
-{"ABATACEPT": 22.914189167139487, "null": 1.6074315812505418}
\ No newline at end of file
+{"null": 0.9643385539623236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12820.json
new file mode 100644
index 00000000000..97ad7edb356
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12820.json
@@ -0,0 +1 @@
+{"ABILIFY": 5.697540464440333, "ADEMPAS": 14.526967068293562, "BENLYSTA": 8.747155227774906, "BYDUREON": 5.203224724300128, "BYETTA": 10.676920687446904, "CIMZIA": 0.8662535081746944, "CLOPIDOGREL": 1.2866009221056207, "COMIRNATY": 0.0352994133912719, "COSENTYX": 1.47072975843905, "CYMBALTA": 1.1197568877815771, "ELIQUIS": 4.855490889300653, "EMPAGLIFLOZIN": 13.872612103885716, "ENTRESTO": 8.420773088242267, "ENTYVIO": 3.006351972693434, "FASLODEX": 3.557521024005386, "GARDASIL": 1.2502838645051604, "HIZENTRA": 10.58519775465012, "IBRANCE": 4.34702561632579, "IBUPROFEN": 3.526900854844486, "JANUMET": 2.7512392486628525, "JANUVIA": 5.880919100784312, "JARDIANCE": 1.1078109352735837, "KEYTRUDA": 0.7690218665985896, "LANTUS": 0.6310062597313819, "LEVETIRACETAM": 2.1132996425311807, "OPSUMIT": 2.7698996326763967, "REVATIO": 5.0709524258068415, "RUCONEST": 41.670516432440685, "SACITUZUMAB": 118.35994500566149, "SIMPONI": 2.0069245222155248, "STELARA": 1.7434084235716676, "SUTENT": 5.697166341222836, "TOVIAZ": 7.170977782469854, "VIAGRA": 2.527710865504817, "XELJANZ": 2.108941469063104, "ZOSTAVAX": 2.637376344150188, "null": 0.8001864679859653}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12821.json
new file mode 100644
index 00000000000..70cb5ca65c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12821.json
@@ -0,0 +1 @@
+{"KEPPRA": 3.041933541681083, "ROTATEQ": 50.16241960286814, "SPINRAZA": 31.273888111899563, "null": 1.6166359076537715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12822.json
new file mode 100644
index 00000000000..c1477b708ba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12822.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12823.json
new file mode 100644
index 00000000000..60a09edb916
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12823.json
@@ -0,0 +1 @@
+{"BIKTARVY": 14.856736575321465, "COMIRNATY": 0.0456356160467029, "HUMALOG": 1.8936439622275043, "INSULIN": 4.222670821182494, "LYRICA": 3.9290047110071926, "SAXENDA": 965.4894508152456, "VICTOZA": 24.622878240214277, "null": 0.4399928848180311}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12824.json
new file mode 100644
index 00000000000..d22ea2347d8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12824.json
@@ -0,0 +1 @@
+{"JAKAVI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12825.json
new file mode 100644
index 00000000000..578045b8806
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12825.json
@@ -0,0 +1 @@
+{"null": 1.810314228943333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12826.json
new file mode 100644
index 00000000000..2e8a666b276
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12826.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 40.37727160752375, "null": 0.1574051806429014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12827.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12827.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12828.json
new file mode 100644
index 00000000000..63731c2ae6e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12828.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 1.6780721290753258, "ANAKINRA": 7.070819348723306, "APIDRA": 6.770497333516218, "ARAVA": 1.6336115992597642, "ATRIPLA": 0.6077261570755886, "AUBAGIO": 8.827274310864322, "CIMZIA": 2.2457892042912224, "COMIRNATY": 0.1982701159241389, "ENBREL": 3.103590403158679, "FIRDAPSE": 12.285128043700904, "GARDASIL": 5.163870363645093, "LANTUS": 12.949701924312976, "LEVEMIR": 5.279897137202243, "MEPOLIZUMAB": 16.193098744715243, "OPTIMARK": 9.718743097686168, "PANTOPRAZOLE": 7.975089934044765, "SPIKEVAX": 0.3808011271642468, "TOZINAMERAN": 0.4296881703323826, "XELJANZ": 1.6026631844616692, "null": 0.8738311656070162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12829.json
new file mode 100644
index 00000000000..8ac95be148c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12829.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.8242182651671777, "ABILIFY": 0.247039632390347, "ACLIDINIUM": 29.27373951055883, "ADALIMUMAB": 1.0368205249752642, "ADCIRCA": 1.6052551241808524, "AFINITOR": 0.8642366532875704, "AIMOVIG": 0.1871626192695873, "ALIMTA": 0.1933436204451729, "ALOXI": 4.279935910714646, "AMBRISENTAN": 2.1236771801334777, "ANORO": 5.523926426806713, "ANTIHYPERTENSIVES": 11.781251254005566, "APIDRA": 0.3946530003150561, "APIXABAN": 12.86555793013557, "ARANESP": 0.1631089409069407, "ARAVA": 0.1449445556335163, "ATRIPLA": 0.0195237363254817, "AVAMYS": 16.31008188742783, "AVANDIA": 0.2170966942172256, "AZOPT": 3.089037889241122, "BENLYSTA": 0.798965074352128, "BENRALIZUMAB": 46.61295754297871, "BIKTARVY": 0.4862902547888178, "BORTEZOMIB": 1.4553700265148397, "BRIDION": 3.9781564798951767, "BRILIQUE": 0.2264251268583847, "BUDESONIDE": 16.156915227122294, "BYDUREON": 0.3005618716193623, "BYETTA": 0.1712402476243697, "CANAGLIFLOZIN": 13.040254279569876, "CARFILZOMIB": 1.1690276576517131, "CAYSTON": 66.64900041729996, "CELECOXIB": 1.5191966543907598, "CHAMPIX": 0.529093428637145, "CHOLESTAGEL": 13.887241566537964, "CICLOSPORIN": 0.2691078744268161, "CIMZIA": 0.1527838770559628, "CLOPIDOGREL": 0.4342393588734362, "COMIRNATY": 0.3603414095721074, "COSENTYX": 1.0657934549573131, "CUBICIN": 0.6117023965038467, "CYMBALTA": 0.1550854393370966, "DARZALEX": 2.8701154299439664, "DAXAS": 30.306131037981448, "DESLORATADINE": 9.891707738466442, "DEXAMETHASONE": 1.1903521639226289, "DINUTUXIMAB": 10.3354758112876, "DOVATO": 6.495201224059108, "DUAKLIR": 15.940806258643969, "DULOXETINE": 0.355733447632194, "DUORESP": 6.244032970582567, "DUPIXENT": 5.744988345896746, "ELIQUIS": 0.7899514686917087, "ENBREL": 0.1188166029219346, "ENTRESTO": 0.3029480165019969, "ENTYVIO": 0.5771733456261329, "ESBRIET": 0.4837651572047343, "ESOMEPRAZOLE": 0.9882634252414404, "EXJADE": 0.1473434121897688, "FASENRA": 7.9860887689176145, "FASLODEX": 0.3096736107254609, "FENTANYL": 1.1394747518945705, "FLEBOGAMMA": 3.5013917888017354, "FLUTICASONE": 23.579238763612658, "GARDASIL": 0.4535601719886392, "GLYCOPYRRONIUM": 41.1164674840245, "HIZENTRA": 1.846174499478587, "HUMALOG": 0.1250821637240844, "HUMAN": 0.8993661143032435, "HUMIRA": 0.1936201132137059, "HYDROCORTISONE": 2.591823319680829, "IBRANCE": 0.2244338180067758, "IBUPROFEN": 0.9132497117692856, "INCRUSE": 10.93235280336004, "INSULIN": 2.131915349406498, "IRBESARTAN": 1.0344117283732648, "IRON": 3.325808651664118, "JANUMET": 0.4718661186952239, "JANUVIA": 0.5114428203323916, "JARDIANCE": 0.0901908555721933, "KALYDECO": 1.5015564182143963, "KEYTRUDA": 0.1005405396786825, "KIOVIG": 1.5888152128809925, "LAMIVUDINE": 0.7264548266143523, "LANTUS": 0.182605490307322, "LEMTRADA": 0.5038385063602695, "LEVOFLOXACIN": 1.0834615584122294, "LIRAGLUTIDE": 37.298549021719374, "LYRICA": 0.4455515709447529, "MEPOLIZUMAB": 42.6197133882217, "METHOTREXATE": 0.1248529790973737, "MICARDIS": 0.7698465585294276, "MIDAZOLAM": 0.5657964645417451, "MMRVAXPRO": 0.2101242794558942, "MULTAQ": 1.6562162373996667, "NAGLAZYME": 1.4715254351263527, "NEULASTA": 0.3287284119144829, "NIMENRIX": 0.3275295291215395, "NOT": 0.6594798826027906, "NUCALA": 37.886920238205946, "OCRELIZUMAB": 0.4232995660575439, "OFEV": 0.5467139963451192, "OMALIZUMAB": 20.958887300906397, "ONCASPAR": 1.3161344426699426, "OPSUMIT": 0.7495543994086248, "ORKAMBI": 2.1138630971925827, "OXYBUTYNIN": 0.9247314094114076, "PANTOPRAZOLE": 5.523094660144454, "PEGASYS": 0.2410298347411473, "PEGINTERFERON": 0.2429935486487628, "PEGINTRON": 0.1496130996967832, "PLAVIX": 0.2184675076528786, "PREGABALIN": 0.5086839687605307, "PREVENAR": 1.4929739245784353, "PRIVIGEN": 3.1923735447008026, "RELVAR": 5.816755531185711, "REVATIO": 0.7491161268858717, "RITUXIMAB": 2.347250931143213, "RIVAROXABAN": 1.5474554333475463, "ROACTEMRA": 0.1629324163073778, "ROTATEQ": 0.3833300775606948, "SEEBRI": 8.824067007485317, "SHINGRIX": 0.1686342238434825, "SIMPONI": 0.2255107186616399, "SPIKEVAX": 0.2390779136835816, "SPIRONOLACTONE": 0.6583861993103886, "STELARA": 0.2433491994255141, "SUBOXONE": 0.1254650330190427, "SUTENT": 0.073392406159737, "SYNAGIS": 9.46888172034534, "TAMIFLU": 0.3935755180987231, "TASIGNA": 0.1588563792054588, "TELMISARTAN": 5.55734223598461, "TICAGRELOR": 0.633876411799067, "TOBI": 9.03421848054096, "TOBRAMYCIN": 1.840128375585952, "TOVIAZ": 0.3750174440293147, "TOZINAMERAN": 0.9720707134493553, "TRACLEER": 0.276666984879424, "TRELEGY": 4.440931772621139, "UMECLIDINIUM": 27.55112427440373, "VAXZEVRIA": 0.3309467627187727, "VFEND": 0.5264023965258984, "VOTRIENT": 0.1488411533889413, "XARELTO": 0.3759169094706831, "XELJANZ": 0.3063092898763302, "XOLAIR": 12.403572838047836, "XTANDI": 0.1258700695777496, "ZOSTAVAX": 0.4984371920973026, "null": 1.1201282548854858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1283.json
index 3d97173bf1b..2d18dd371ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1283.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1283.json
@@ -1 +1 @@
-{"ABACAVIR": 9.520238510807271, "ABATACEPT": 39.72721745231772, "ADALIMUMAB": 125.36099498307053, "AFINITOR": 2.5560390220774245, "ARAVA": 2.031472754369356, "BOTULINUM": 17.62389774736483, "ENTYVIO": 3.2361674379192857}
\ No newline at end of file
+{"COMIRNATY": 0.1960915523609841, "null": 2.0217007691641986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12830.json
new file mode 100644
index 00000000000..b193018d46b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12830.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 9.216198671557253}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12831.json
new file mode 100644
index 00000000000..5e7ef3ac0e5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12831.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 0.7341963397949917, "null": 0.5695777329702261}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12832.json
new file mode 100644
index 00000000000..8db1bf87d97
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12832.json
@@ -0,0 +1 @@
+{"ABATACEPT": 5.24049227373138, "ARAVA": 14.849090686680473, "AZACITIDINE": 14.751921149380658, "BEVACIZUMAB": 3.1660441204517054, "BOSULIF": 8.28320962830743, "COMIRNATY": 0.0332628431819978, "CYMBALTA": 1.674175753290404, "CYTARABINE": 6.951199444951618, "FASLODEX": 3.0723644565710497, "IBRANCE": 14.032105495544236, "JAKAVI": 4.444433644621477, "KEYTRUDA": 0.9333981796053964, "LEFLUNOMIDE": 8.763794364786644, "LEMTRADA": 9.315344542863883, "NEULASTA": 86.49372363947388, "PEGASYS": 3.66934892534104, "PEGINTRON": 3.894777321082533, "PLEGRIDY": 6.078209131308134, "SOLIRIS": 2.6064630792949943, "SPRYCEL": 3.2207737585495084, "SUTENT": 0.4056591104815084, "null": 0.4799920290093332}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12833.json
new file mode 100644
index 00000000000..00431e03470
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12833.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.1719015140812658, "ABEMACICLIB": 3.8952560166661834, "ABILIFY": 0.2714322647799544, "ABRAXANE": 2.5571074605085102, "ACTOS": 0.7402631215358019, "ADCETRIS": 5.397435728311549, "ADCIRCA": 0.7730067511905894, "AFINITOR": 1.138169659746791, "AIMOVIG": 0.0616192908568942, "ALEMTUZUMAB": 0.4468287369916169, "ALIMTA": 3.7213138808959054, "ARANESP": 0.5107814435716713, "ARAVA": 0.3431975414360999, "ARIPIPRAZOLE": 1.0856389883605584, "ASPARAGINASE": 1.0927360741236012, "ATEZOLIZUMAB": 2.5620389904673067, "ATRIPLA": 0.0309105825631274, "AUBAGIO": 1.155045821430552, "AVANDIA": 0.0441703120896942, "AVASTIN": 6.857434178679004, "AXICABTAGENE": 2.602999876440353, "AZACITIDINE": 6.574248365810278, "AZATHIOPRINE": 0.534719771994346, "BARACLUDE": 1.2682904665388754, "BEDAQUILINE": 1.067713262980436, "BENLYSTA": 0.5766318035928856, "BETAFERON": 0.9186393650235412, "BEVACIZUMAB": 6.609199547589163, "BOCEPREVIR": 2.1123775493664323, "BORTEZOMIB": 1.5816001847792576, "BOSULIF": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12834.json
new file mode 100644
index 00000000000..5c191798554
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12834.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.2787573242304741, "ABILIFY": 0.3344099825037303, "ADALIMUMAB": 0.1602371599934462, "AFINITOR": 1.1062692169515391, "AIMOVIG": 0.2420081684812267, "ALIMTA": 1.049355867572267, "AMINOSALICYLIC": 4.480569499568634, "APREPITANT": 1.5635902189867312, "ARANESP": 0.6309259951983921, "ARAVA": 0.1761983858487431, "ARIPIPRAZOLE": 2.200471054833264, "ASPARAGINASE": 0.5868539657763497, "AUBAGIO": 0.3933834464377182, "AVASTIN": 0.953425647878031, "AZACITIDINE": 1.4781894158161208, "AZATHIOPRINE": 0.7297340689531541, "BEDAQUILINE": 14.272584841663406, "BENLYSTA": 0.8694061852574493, "BEVACIZUMAB": 1.3800168301233935, "BOSULIF": 5.444052942759177, "BRUKINSA": 10.603829055390763, "BUDESONIDE": 0.2841491671901219, "BYDUREON": 0.3886340805319939, "BYETTA": 0.5017604442910849, "CANCIDAS": 7.747444881457829, "CAPECITABINE": 1.4119176831764315, "CARFILZOMIB": 1.826086631428527, "CELLCEPT": 1.5501929011567586, "CHAMPIX": 0.3662342293114467, "CICLOSPORIN": 1.4548088058579276, "CIMZIA": 0.6691290279976643, "CLOPIDOGREL": 1.584801650087847, "COMIRNATY": 0.2537169237351504, "COMTAN": 1.6373469149892663, "COSENTYX": 0.96314915438687, "CUBICIN": 3.0042416157594496, "CYMBALTA": 0.4407815574059199, "CYTARABINE": 1.3142463809319729, "DASATINIB": 4.244033656790984, "DELAMANID": 2.3236678106309725, "DEXAMETHASONE": 1.6024116902144434, "DIFICLIR": 10.66004736241396, "DOCETAXEL": 2.098273468327702, "DOXORUBICIN": 1.9493173469450849, "ELIQUIS": 0.2785304053175177, "EMEND": 3.443072677915566, "ENBREL": 0.4183956758313149, "ENTRESTO": 0.4232204708739594, "ENTYVIO": 1.6198574676231048, "ESBRIET": 0.9649884545643064, "EVISTA": 1.4157609254391774, "EXFORGE": 0.7146226461895177, "EXJADE": 6.8866689573615645, "FAMPYRA": 1.2015910507353806, "FASENRA": 0.712417198742373, "FASLODEX": 1.0056867203610929, "FENTANYL": 0.6092868474853369, "FILGRASTIM": 6.606922576013664, "FULVESTRANT": 0.9373382052317396, "GARDASIL": 0.4069386494107683, "GLIVEC": 7.8066515084351025, "HIZENTRA": 0.6536199430213993, "HUMALOG": 0.3718844530509864, "HUMIRA": 1.8946240236240317, "IBRANCE": 1.0160461135465642, "IBUPROFEN": 0.6269125015370234, "ICLUSIG": 2.877212941188598, "IMATINIB": 5.725177995073194, "IMBRUVICA": 4.245978986419565, "INFLIXIMAB": 1.7331168462167283, "INLYTA": 0.6386995263233683, "IRESSA": 0.8005497771024779, "JAKAVI": 21.36599278360437, "JANUMET": 0.3031072470344161, "JANUVIA": 0.9390671505061946, "JARDIANCE": 0.7486373189501032, "JEVTANA": 2.411782249584394, "KALETRA": 0.9627929972249888, "KEPPRA": 0.4695889757769836, "KEYTRUDA": 1.417661806700891, "KYMRIAH": 2.604793675326871, "LANTUS": 0.3714678993538399, "LATUDA": 1.166536005248866, "LEMTRADA": 3.957638676110964, "LENVIMA": 1.3310850928058309, "LEVOFLOXACIN": 1.6700512272255157, "LYRICA": 1.1687573914958331, "MEKINIST": 1.0017730862614689, "METHOTREXATE": 1.2975563619445902, "MICARDIS": 0.6680717464053635, "MYCOPHENOLATE": 0.9069347351734646, "NEULASTA": 11.988321634637789, "NEXAVAR": 0.996369341782026, "NILOTINIB": 3.851428504206577, "NPLATE": 4.053401208383998, "NUCALA": 0.4171666757113035, "OFEV": 0.6212592085687839, "OLANZAPINE": 3.8542104806507615, "OLYSIO": 2.0559923532803994, "OPDIVO": 0.6133291498623643, "OPSUMIT": 1.5855169274567449, "PANTOPRAZOLE": 0.6344555363584475, "PEGASYS": 0.6061821825448025, "PEGINTERFERON": 0.5229775552601764, "PEGINTRON": 0.89945310507226, "PIOGLITAZONE": 6.862236654663247, "PLAVIX": 0.700867011697839, "PROTELOS": 6.889105111042243, "REMICADE": 2.4305358712559992, "RIBAVIRIN": 0.5835143853987957, "RINVOQ": 1.8125472733718129, "RITUXIMAB": 1.0681003483652916, "ROACTEMRA": 0.7150353221933489, "ROTATEQ": 0.9230705850324862, "RUXOLITINIB": 14.499944644970236, "SIMPONI": 0.2798102724038703, "SOLIRIS": 1.8312498979691387, "SPIKEVAX": 0.140489008953164, "SPINRAZA": 0.980571319530042, "SPRYCEL": 3.6235320047540127, "STELARA": 1.2565956122311943, "STIVARGA": 1.345666142935544, "SUBOXONE": 0.3021090871006577, "SUTENT": 0.5062357289498024, "SYNAGIS": 0.7785059251810292, "TAMIFLU": 1.3014153941871147, "TASIGNA": 7.072907915485345, "TOBRAMYCIN": 4.033757670819093, "TORISEL": 1.84260318132068, "TOZINAMERAN": 0.670181723783737, "TRACLEER": 1.640115105540314, "TRELEGY": 0.7818851815918141, "TREMFYA": 1.899412437390218, "TRISENOX": 9.471881009222107, "VAXZEVRIA": 0.0431876881673088, "VENCLYXTO": 4.470140686400225, "VENETOCLAX": 3.782038552988482, "VFEND": 1.210270631271792, "VIAGRA": 0.3998502181635084, "VORICONAZOLE": 1.2028355083002378, "VOTRIENT": 0.35839678766858, "XELJANZ": 1.478865946122633, "XOLAIR": 2.229459881079572, "XTANDI": 0.2159921533798232, "ZONISAMIDE": 6.167816477328346, "ZOSTAVAX": 0.4626900392829159, "ZYPADHERA": 1.6185767604466144, "ZYPREXA": 2.9689807592004023, "null": 1.58054265028603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12835.json
new file mode 100644
index 00000000000..aa9d2714c49
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12835.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 29.923361968674733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12836.json
new file mode 100644
index 00000000000..377a91ef4fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12836.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1315566242936289, "IBRANCE": 7.522830184668925, "JAKAVI": 9.016113615257112, "KEPPRA": 1.7697067973375302, "NEULASTA": 28.4043541912802, "PEGASYS": 7.37444050070655, "SPIKEVAX": 0.148795214332525, "SUTENT": 1.6319307463655826, "VAXZEVRIA": 0.0918299676574274, "null": 0.9978939392641322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12837.json
new file mode 100644
index 00000000000..92b0750930f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12837.json
@@ -0,0 +1 @@
+{"ATRIPLA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12838.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12838.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12839.json
new file mode 100644
index 00000000000..40beb64c39e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12839.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4483162171989844, "null": 0.6498094362430618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1284.json
index 04da9430fbb..af09adb1db6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1284.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1284.json
@@ -1 +1 @@
-{"ABATACEPT": 88.56662650220915, "ADALIMUMAB": 98.71541496978408, "AIMOVIG": 7.79228822361316, "AMINOSALICYLIC": 27.97891107944217, "APREMILAST": 18.235486175493147, "ARAVA": 3.725126325368865, "BOTULINUM": 7.2486668466569455, "CERTOLIZUMAB": 43.569845236308325, "RITUXIMAB": 1.9787036286955877}
\ No newline at end of file
+{"null": 5.195249144307421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12840.json
new file mode 100644
index 00000000000..976a261a998
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12840.json
@@ -0,0 +1 @@
+{"ADENURIC": 59.32756749472371, "ALEMTUZUMAB": 36.658149077224735, "BEDAQUILINE": 23.73431312126392, "COMIRNATY": 0.2144768249983729, "LEMTRADA": 25.172437837227594, "null": 0.9433982813175986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12841.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12841.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12842.json
new file mode 100644
index 00000000000..d9912df3b22
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12842.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 0.7511235904496588, "null": 0.6032715149120254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12843.json
new file mode 100644
index 00000000000..8c7a4766c82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12843.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3926463387781681, "CYTARABINE": 46.76206415659838, "HUMIRA": 10.040674318241368, "LACOSAMIDE": 91.1754273084334, "SPIKEVAX": 0.3616201974974849, "VAXZEVRIA": 0.2499464007215354, "null": 0.5855257002259917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12844.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12844.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12845.json
new file mode 100644
index 00000000000..135450ac247
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12845.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.9245049128236291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12846.json
new file mode 100644
index 00000000000..f984557c4c5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12846.json
@@ -0,0 +1 @@
+{"SIMPONI": 25.182102751763047, "null": 0.9975084484595548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12847.json
new file mode 100644
index 00000000000..207ba3ddc7f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12847.json
@@ -0,0 +1 @@
+{"null": 4.40329870614908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12848.json
new file mode 100644
index 00000000000..434651db3c1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12848.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.218997335769142, "null": 3.079990158712987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12849.json
new file mode 100644
index 00000000000..902e5b7eea5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12849.json
@@ -0,0 +1 @@
+{"ENTECAVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1285.json
index 3575a22858a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1285.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1285.json
@@ -1 +1 @@
-{"AFINITOR": 20.87903442957103, "FASLODEX": 72.81054938735434, "IBRANCE": 24.077295070764603}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12850.json
new file mode 100644
index 00000000000..2c8e0376f95
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12850.json
@@ -0,0 +1 @@
+{"MANNITOL": 843.2177030145225, "null": 2.275950152340357}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12851.json
new file mode 100644
index 00000000000..3aaff5cd3f2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12851.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.0414624674559276, "ARIPIPRAZOLE": 1.0901173793431589, "BENZODIAZEPINE": 5.511732148399275, "BREXPIPRAZOLE": 36.616543468221806, "BRINTELLIX": 2.69585289466456, "BUPIVACAINE": 6.499582205780106, "BUPRENORPHINE": 12.953167806266832, "BUVIDAL": 60.19141039914823, "CANNABIDIOL": 3.01035476977939, "CAPSAICIN": 17.252122727912, "CARIPRAZINE": 13.889161987240223, "CHAMPIX": 4.110460527981488, "CLOPIDOGREL": 0.2520463341870342, "COMIRNATY": 0.0068554121299785, "CRIXIVAN": 1.842084945619452, "CYMBALTA": 9.560386756140415, "DEXDOR": 16.982351414976133, "DEXMEDETOMIDINE": 15.243475168220606, "DULOXETINE": 1.6177469772049131, "FENTANYL": 4.753879545721105, "HYDROCORTISONE": 0.6384773234107676, "IBUPROFEN": 0.7647183675769347, "IRBESARTAN": 0.8247761732540143, "JAKAVI": 2.0764127834388124, "KEPPRA": 1.0647292075113062, "LANTUS": 0.146063085647956, "LATUDA": 3.3743231697275164, "LEVETIRACETAM": 0.5610626008163057, "LEVODOPA": 4.537739524851074, "LEVOFLOXACIN": 0.3511827886962523, "LURASIDONE": 16.10687412437745, "LYRICA": 7.04495950750995, "MEPOLIZUMAB": 0.2887665595916371, "MIDAZOLAM": 4.03602798703815, "NALMEFENE": 86.23155975683488, "NOT": 1.957847405913912, "NUCALA": 0.3517085249244686, "OLANZAPINE": 2.7164537474532624, "OXYBUTYNIN": 2.3781146169863603, "PANTOPRAZOLE": 0.8246014702652337, "PEGASYS": 0.1806985609616632, "POPPERS": 18.629403926374323, "PREGABALIN": 7.8924823094274945, "PRIALT": 15.497529369547182, "RISPERIDONE": 1.829019366326052, "RUXOLITINIB": 2.190008556525572, "SELINCRO": 146.44392034752178, "SIFROL": 4.069195062798588, "SPIKEVAX": 0.0072872882395482, "SUBOXONE": 7.575617853240657, "SUFENTANIL": 2.6950279545415987, "TOVIAZ": 1.6195953203522448, "TOZINAMERAN": 0.0538169260062075, "VAXZEVRIA": 0.0714911393660968, "XARELTO": 0.9457859085968092, "XELJANZ": 0.1098007500394506, "XYREM": 1.8871868096057307, "ZYPREXA": 2.3421312800579845, "null": 5.764445946591517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12852.json
new file mode 100644
index 00000000000..6e426402c5c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12852.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.227107914771714, "null": 1.6220135734691283}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12853.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12853.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12854.json
new file mode 100644
index 00000000000..36b6ca09b3d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12854.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 2.4507760237035305, "ABATACEPT": 6.751327164317323, "ABILIFY": 5.413631529546075, "ADALIMUMAB": 13.088414340167366, "AFINITOR": 0.2526074028344798, "AIMOVIG": 0.2045488189262566, "ALDARA": 6.54505246652725, "APIDRA": 0.3571968640447475, "APREMILAST": 2.428650396518941, "ARAVA": 42.460621581832434, "AUBAGIO": 0.5150919358494231, "BENLYSTA": 3.149208206629555, "CABOMETYX": 0.5272057185976307, "CHAMPIX": 0.1849890117439196, "CICLOSPORIN": 0.1283582357635454, "CIMZIA": 1.9071515881760623, "CLOPIDOGREL": 0.2861111578381824, "COMIRNATY": 0.1336550136546902, "COSENTYX": 1.2722079178798342, "CYMBALTA": 0.3071876528420353, "DEXAMETHASONE": 0.2169666361479467, "ELIQUIS": 0.7540069774373694, "ENBREL": 0.2250255616921652, "ENTRESTO": 0.4367158794664754, "EXFORGE": 0.443648432730153, "EXJADE": 0.5653142904338931, "FIRDAPSE": 1.6652105508751678, "FORSTEO": 0.7862034936552134, "FORXIGA": 0.5699920028157583, "FULVESTRANT": 1.9015736488407016, "GARDASIL": 0.1972483947763377, "HIZENTRA": 0.9288841524784096, "HUMALOG": 1.3411835565170007, "HUMIRA": 0.3277582700262945, "IBRANCE": 1.0888166816173832, "ILARIS": 27.97323113945542, "INLYTA": 0.9187113687583852, "INSULIN": 0.6758107808462754, "JANUVIA": 0.2952610382797396, "JARDIANCE": 1.0228176039246433, "KEYTRUDA": 0.1584975874574298, "LANTUS": 0.9711914792135632, "LEFLUNOMIDE": 2.1826768333815227, "MEKINIST": 0.5059966820526118, "MELATONIN": 1.534363023114151, "MEPOLIZUMAB": 1.5340951607616868, "METHOTREXATE": 0.4463553254476996, "NEXAVAR": 0.3476520607069178, "OMALIZUMAB": 0.41134899304811, "OPSUMIT": 0.3386686337584453, "OPTIMARK": 1.1372322263237802, "PEGASYS": 0.2485908665212894, "PLAVIX": 0.2070367942428756, "REMICADE": 1.8244265579738392, "REVATIO": 0.7676844462794857, "RINVOQ": 0.4441704514407545, "RITUXIMAB": 1.022146006136624, "ROACTEMRA": 0.6842914605650852, "SHINGRIX": 0.4171392004693435, "SIMPONI": 1.4251709789943914, "SOLIRIS": 0.3250959632098461, "SPIKEVAX": 0.1301637239126521, "STELARA": 0.4975965561432258, "SUTENT": 2.438657392517346, "TOZINAMERAN": 0.1347325727673211, "VAXZEVRIA": 0.0744503376300009, "VOTRIENT": 1.1828581870630712, "XELJANZ": 1.1204756664244444, "XOLAIR": 0.8032432437647554, "ZOSTAVAX": 0.3509798851488349, "ZYCLARA": 7.659344187584155, "ZYPREXA": 0.4880279741861326, "null": 0.3287577176725529}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12855.json
new file mode 100644
index 00000000000..dda96e5e978
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12855.json
@@ -0,0 +1 @@
+{"null": 0.5049055256884603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12856.json
new file mode 100644
index 00000000000..4b03a87d1b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12856.json
@@ -0,0 +1 @@
+{"ABILIFY": 30.33072418841629, "ADALIMUMAB": 2.270414829792151, "COMIRNATY": 0.3573307474344459, "HUMALOG": 2.2230443290217243, "HUMIRA": 11.435098905172325, "IBRANCE": 2.05245885469728, "NEXOBRID": 685.2061884811179, "SIMPONI": 4.238256399017906, "SPIKEVAX": 0.2018093279208893, "SUTENT": 4.901226216271909, "null": 0.777680073715675}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12857.json
new file mode 100644
index 00000000000..21a8b709818
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12857.json
@@ -0,0 +1 @@
+{"null": 0.7673534021882098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12858.json
new file mode 100644
index 00000000000..bdae5da7c74
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12858.json
@@ -0,0 +1 @@
+{"AVASTIN": 15.863090890130284, "BEVACIZUMAB": 35.15566101945881, "CELLCEPT": 6.644874182438467, "CICLOSPORIN": 3.417448058942931, "FAMPRIDINE": 210.17914583594228, "HUMIRA": 6.317050251849163, "IRON": 39.9867188551227, "KEPPRA": 7.563922500041955, "NEXAVAR": 3.5971583132565668, "SUTENT": 4.327082968466441, "TOVIAZ": 28.50521307785547, "null": 0.8388293602011238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12859.json
new file mode 100644
index 00000000000..8b60fccf836
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12859.json
@@ -0,0 +1 @@
+{"TOVIAZ": 169.6004886034721, "null": 1.4839157701293522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1286.json
index 20ccf4416ec..1fa6dff8f1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1286.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1286.json
@@ -1 +1 @@
-{"ACLIDINIUM": 133.00163975369662, "ANORO": 25.051756487839278, "BYETTA": 10.777439124763731, "IBRANCE": 5.356533999489099, "KEYTRUDA": 2.521082005800652, "XOLAIR": 6.142662017505936, "null": 3.145446526419118}
\ No newline at end of file
+{"PEGINTRON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12860.json
new file mode 100644
index 00000000000..2e41c9aac30
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12860.json
@@ -0,0 +1 @@
+{"null": 1.3831845382419907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12861.json
new file mode 100644
index 00000000000..38286659292
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12861.json
@@ -0,0 +1 @@
+{"APIXABAN": 2.6832565421810672, "BRILIQUE": 12.17695853632586, "CLOPIDOGREL": 7.101262097677275, "COMIRNATY": 0.1599398723794724, "ELIQUIS": 26.6576134021558, "FIRDAPSE": 12.983648366956718, "IBRANCE": 1.1443651105955084, "LIXIANA": 12.236597067269292, "PLAVIX": 11.015713966811186, "SPIKEVAX": 0.2292151110768168, "SUTENT": 2.595067978966173, "TOZINAMERAN": 0.4642784163831789, "VAXZEVRIA": 0.2274597555978178, "XARELTO": 13.521369733008749, "null": 1.046728247673788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12862.json
new file mode 100644
index 00000000000..37d73b9adc5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12862.json
@@ -0,0 +1 @@
+{"ABATACEPT": 8.118497490867515, "ADALIMUMAB": 10.921455017242142, "AFINITOR": 1.654276654659277, "ARAVA": 0.8367685695214421, "AUBAGIO": 1.4421331210568014, "AVASTIN": 7.558858208689822, "BENLYSTA": 2.7632341605416224, "BEVACIZUMAB": 4.874813401381169, "CICLOSPORIN": 1.8263227738262884, "CIMZIA": 1.7256036760617206, "COMIRNATY": 0.0461536848809835, "COSENTYX": 2.3424363049293078, "ELIQUIS": 1.1189096559133325, "EXJADE": 2.223586435813285, "FIRDAPSE": 7.93707873892532, "HIZENTRA": 3.262221942324613, "HUMALOG": 3.0539794830308247, "IBRANCE": 2.320097761082506, "IBUPROFEN": 1.8026606837405923, "ILARIS": 220.4631259569844, "INSULIN": 1.8920948154341672, "LANTUS": 1.4239727240899254, "MEPOLIZUMAB": 6.120710053218754, "MYCOPHENOLATE": 7.200708827071009, "NEXOBRID": 560.1063922133287, "RITUXIMAB": 2.016463340231286, "ROACTEMRA": 4.690500675563875, "SIMPONI": 2.471649819295023, "SOMAVERT": 82.84083206435105, "STELARA": 1.0351942018378415, "SUTENT": 2.8503196032162275, "XELJANZ": 6.105363076197313, "null": 0.6495244003892353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12863.json
new file mode 100644
index 00000000000..ed0caf3bbad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12863.json
@@ -0,0 +1 @@
+{"null": 0.3862976464495503}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12864.json
new file mode 100644
index 00000000000..3bb40932587
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12864.json
@@ -0,0 +1 @@
+{"null": 0.4340993310328067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12865.json
new file mode 100644
index 00000000000..07692293386
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12865.json
@@ -0,0 +1 @@
+{"CUBICIN": 30.984574869612715, "KEPPRA": 7.834793725380163, "null": 0.9167550431945216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12866.json
new file mode 100644
index 00000000000..fe9fb53e246
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12866.json
@@ -0,0 +1 @@
+{"LANTUS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12867.json
new file mode 100644
index 00000000000..3a3aefed138
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12867.json
@@ -0,0 +1 @@
+{"null": 0.7582163753876437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12868.json
new file mode 100644
index 00000000000..d6c77816b9c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12868.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.935719936416546, "CLOPIDOGREL": 2.2734867750049794, "COMIRNATY": 0.1444213492773217, "COSENTYX": 5.911723810487288, "ELIQUIS": 1.2414009478952512, "ERTAPENEM": 213.49207905415952, "HUMIRA": 4.85127272462081, "SUTENT": 1.4372778838105509, "XELJANZ": 4.196274790902783, "null": 1.7191478561364688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12869.json
new file mode 100644
index 00000000000..895aba44e78
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12869.json
@@ -0,0 +1 @@
+{"null": 1.1724972826029354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1287.json
index 7960ccfbeb1..ed756a6b9a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1287.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1287.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6460669311753673, "null": 1.4350502100716538}
\ No newline at end of file
+{"OLANZAPINE": 268.93473243736827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12870.json
new file mode 100644
index 00000000000..ea88d801945
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12870.json
@@ -0,0 +1 @@
+{"null": 1.098636622713017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12871.json
new file mode 100644
index 00000000000..0bdada81ff7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12871.json
@@ -0,0 +1 @@
+{"ABATACEPT": 15.488297320208538, "ARAVA": 7.603732980281528, "ENBREL": 97.53003668769182, "HUMIRA": 20.90761609703098, "null": 0.5696393258465648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12872.json
new file mode 100644
index 00000000000..50c35c89db5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12872.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.541691848078728, "ATRIPLA": 25.625025232738203, "AUBAGIO": 0.97020548848416, "AVANDIA": 0.8174384894539168, "BENRALIZUMAB": 79.0122051594238, "CIMZIA": 0.6769055325047018, "COMIRNATY": 0.0161185733342876, "CYMBALTA": 0.5051102430667207, "ELIQUIS": 0.909917269231472, "EVENITY": 11.054667842951089, "EVISTA": 8.68471255513968, "EXFORGE": 2.537606806803676, "FIRDAPSE": 3.720009960551506, "FORSTEO": 11.449877682352518, "HUMALOG": 1.612477286425282, "HUMIRA": 1.0276792344182129, "IBRANCE": 1.9230528645546825, "LANTUS": 2.320442188309193, "LYRICA": 1.1843965821675444, "METHOTREXATE": 0.9996485147716504, "OMALIZUMAB": 1.0179736104805857, "OPSUMIT": 0.688742068056654, "PEGASYS": 0.4126024861423922, "REVATIO": 2.984178247355816, "RIVASTIGMINE": 133.4719166609001, "SIMPONI": 1.470637818475522, "STELARA": 0.668704255624582, "STRIBILD": 12.41062327368115, "SUBOXONE": 2.803733551072662, "TOVIAZ": 2.138625514083853, "TRELEGY": 1.2869932712378664, "TRUVADA": 13.115803347275715, "VIAGRA": 1.0594863471568052, "VIREAD": 8.21730543076955, "XELJANZ": 3.843911012183144, "XOLAIR": 1.2565231078146444, "XTANDI": 0.6480263258636009, "ZOSTAVAX": 1.1735812304541702, "null": 0.6933413187387782}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12873.json
new file mode 100644
index 00000000000..a3b371cca46
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12873.json
@@ -0,0 +1 @@
+{"ARAVA": 7.659872583032724, "SIMPONI": 13.53340281014781, "null": 1.1015772843865073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12874.json
new file mode 100644
index 00000000000..cd6a488d6b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12874.json
@@ -0,0 +1 @@
+{"null": 1.0160645214141928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12875.json
new file mode 100644
index 00000000000..ea580aa0f68
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12875.json
@@ -0,0 +1 @@
+{"LANTUS": 21.30966947723932, "null": 1.3477597073241303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12876.json
new file mode 100644
index 00000000000..36ec61c3486
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12876.json
@@ -0,0 +1 @@
+{"null": 4.8229311646374615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12877.json
new file mode 100644
index 00000000000..91f607b2cac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12877.json
@@ -0,0 +1 @@
+{"null": 1.7549413295032312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12878.json
new file mode 100644
index 00000000000..3c4d0764685
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12878.json
@@ -0,0 +1 @@
+{"ELIQUIS": 2.001134232905128, "HUMALOG": 1.8896957000494736, "KEPPRA": 6.752981586703715, "LANTUS": 1.242349756354141, "OPSUMIT": 5.008766535083606, "STELARA": 2.866702156679754, "XELJANZ": 2.2819033598978127, "null": 3.1445803135810007}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12879.json
new file mode 100644
index 00000000000..43dec1b815d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12879.json
@@ -0,0 +1 @@
+{"null": 4.904746991431914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1288.json
index 3eccc005eaf..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1288.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1288.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1703937439456462, "FULVESTRANT": 21.601470772894395, "GARDASIL": 4.038560196684616, "PEGASYS": 1.966502389419294, "null": 1.6151205467284229}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12880.json
new file mode 100644
index 00000000000..7051265aa55
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12880.json
@@ -0,0 +1 @@
+{"BRINTELLIX": 22.745734156017445, "DULOXETINE": 37.14795153247491, "KEPPRA": 15.539184202140708, "OLANZAPINE": 17.456980842245745, "null": 1.2498419695807526}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12881.json
new file mode 100644
index 00000000000..2be0e1a98e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12881.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.9833393767355016, "APROVEL": 10.504769856100603, "CYMBALTA": 2.037736857575716, "DAPTOMYCIN": 134.8817577338964, "ELIQUIS": 3.715702546263677, "FYCOMPA": 17.40906569057788, "HUMALOG": 7.186967733944446, "IRBESARTAN": 25.572174983357847, "KEPPRA": 6.923945029528878, "LACOSAMIDE": 17.463635005115616, "LEVETIRACETAM": 2.218197256067405, "LYRICA": 4.61745672815892, "MIDAZOLAM": 7.322031489116171, "OLANZAPINE": 11.01215987033834, "PREGABALIN": 10.00994560728853, "RISPERIDONE": 19.8768074989713, "SITAGLIPTIN": 94.19399297381086, "ZYPREXA": 2.4635423448112053, "null": 2.5520562130069893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12882.json
new file mode 100644
index 00000000000..3bd11550372
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12882.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 12.477415229121013, "ACTRAPID": 16.329528189158147, "APIDRA": 72.09983406611124, "APROVEL": 2.118230643852501, "BRIDION": 2.595042666644182, "CHLORHEXIDINE": 10.970524853087676, "COMIRNATY": 0.1907806184966578, "CYMBALTA": 0.1662949538329526, "DAPTOMYCIN": 30.46158083737492, "DESLORATADINE": 5.331284447257246, "DEXAMETHASONE": 0.5461306677553122, "ELIQUIS": 0.1683036610090275, "EXFORGE": 1.338208796307644, "FENTANYL": 2.193032289271478, "FIASP": 48.503592920981546, "GARDASIL": 1.9510710413818664, "HUMALOG": 26.60027806653665, "INSULATARD": 21.98845063315312, "INSULIN": 13.544522208943585, "IRBESARTAN": 2.127178100957832, "JANUMET": 1.6369527004106896, "KEPPRA": 2.176759455546631, "LANTUS": 7.689194607741006, "LEVEMIR": 19.17095747440093, "LEVETIRACETAM": 0.9239528850969508, "LYRICA": 0.5346819463750676, "MEPOLIZUMAB": 1.849642046958868, "MIDAZOLAM": 1.8349624401407207, "MMRVAXPRO": 0.5942158316938392, "NOVOMIX": 83.92931315587076, "NOVORAPID": 12.169393862975722, "OLANZAPINE": 0.7929395141002836, "PANTOPRAZOLE": 1.2330703591362997, "PROQUAD": 42.33311135124024, "SHINGRIX": 0.497832760764238, "SPIKEVAX": 0.0836150349806696, "TOZINAMERAN": 0.1842198593042088, "TWINRIX": 3.039309237229864, "VAXZEVRIA": 0.0561612609714139, "VIAGRA": 0.606099665128234, "ZOSTAVAX": 0.4305786710419349, "null": 1.7778380342990796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12883.json
new file mode 100644
index 00000000000..25ed9eabde3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12883.json
@@ -0,0 +1 @@
+{"null": 10.0925420073731}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12884.json
new file mode 100644
index 00000000000..b7efdc13fcb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12884.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3344930198950464, "null": 2.594939592130261}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12885.json
new file mode 100644
index 00000000000..db54a9693be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12885.json
@@ -0,0 +1 @@
+{"null": 4.832728515443844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12886.json
new file mode 100644
index 00000000000..12d4ca9f135
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12886.json
@@ -0,0 +1 @@
+{"AIMOVIG": 3.505792839102841, "ANORO": 22.184309370255598, "APIDRA": 7.3483526810313, "BENLYSTA": 13.667536751165205, "BYDUREON": 33.77845537236623, "BYETTA": 3.4736591190419754, "CICLOSPORIN": 0.5602924827535963, "COSENTYX": 2.8694225534210944, "FASENRA": 14.47628150270339, "FIASP": 9.870899817844604, "INCRUSE": 24.373815622404315, "INSULIN": 1.7727391148058862, "LANTUS": 12.03046236401724, "MOVYMIA": 169.257777761374, "NEULASTA": 5.898162686277333, "NOVORAPID": 5.8938025206347975, "NUCALA": 7.751502087395275, "RELVAR": 14.33720168115818, "TERROSA": 44.20027338226655, "TOUJEO": 23.08276218074281, "TRELEGY": 69.04004903532625, "null": 2.6158460763500195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12887.json
new file mode 100644
index 00000000000..9df68aea44c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12887.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 2.684229180269249, "ABILIFY": 3.387649586282831, "ACTRAPID": 3.2197153790718134, "ADENURIC": 5.085637849223192, "AERIUS": 1.2803356581827845, "AFINITOR": 0.3205445550029284, "AIMOVIG": 7.932826562086667, "ANORO": 0.9102838555056696, "APIDRA": 2.171996479576765, "APIXABAN": 0.1332637256534579, "APROVEL": 2.282583730077586, "ARANESP": 0.9693423647001024, "ARIPIPRAZOLE": 0.3691678878444488, "AUBAGIO": 0.2391278723227189, "AVAMYS": 0.5884991489162256, "BARACLUDE": 1.125507269637487, "BENLYSTA": 0.5049656850404012, "BENRALIZUMAB": 2.408558947536545, "BETAFERON": 1.2710883631730772, "BETMIGA": 5.946208146776063, "BIKTARVY": 4.014739647276096, "BONVIVA": 1.487959365193635, "BRAFTOVI": 0.5054757837492558, "BRILIQUE": 0.5508163458875189, "BRINTELLIX": 4.644320877697612, "BRIVIACT": 2.4779219780893005, "BUDESONIDE": 0.2730257164734834, "BUPRENORPHINE": 2.938300600014369, "BYDUREON": 2.588771715187087, "BYETTA": 0.4261523348764101, "CABOMETYX": 0.4366255858700625, "CABOTEGRAVIR": 5.283241630417883, "CARBIDOPA": 3.840013046378513, "CELLCEPT": 0.4011955030097805, "CHAMPIX": 0.3668881283514466, "CICLOSPORIN": 0.087363914193387, "CIMZIA": 0.2143488682327271, "CIRCADIN": 4.568922209900865, "CLOPIDOGREL": 0.6206674606875793, "COAPROVEL": 3.1839773380755174, "COMIRNATY": 0.0199429705864827, "COMTAN": 13.49851266687642, "COPALIA": 24.675147702071957, "COSENTYX": 0.5879281550312416, "COTELLIC": 0.9543670306750176, "CYMBALTA": 1.052108544293566, "CYTARABINE": 0.1664858083575544, "DAFIRO": 13.0030641247141, "DAPAGLIFLOZIN": 2.320587206263502, "DARZALEX": 0.7898529784591141, "DESCOVY": 2.527997699987852, "DESLORATADINE": 1.410566794905869, "DIFICLIR": 8.015360503660864, "DULOXETINE": 0.4404471774481436, "EFIENT": 1.764958590941585, "ELIQUIS": 2.304515347764125, "EMEND": 1.611517052174581, "EMTRICITABINE": 1.3269830234922635, "ENBREL": 0.2430103982869018, "ENTACAPONE": 2.7074472992354206, "ENTRESTO": 13.034081218463443, "EPCLUSA": 1.4319644550522856, "ERLEADA": 0.7471934643898288, "EUCREAS": 1.5037396330153143, "EVRA": 11.930155209492296, "EXELON": 3.25153303923832, "EXFORGE": 11.309267465121987, "EXJADE": 0.6509976980949765, "EYLEA": 6.928798483857624, "FAMPYRA": 0.4654913666980021, "FASENRA": 0.3274333749403033, "FASLODEX": 0.6539579734298331, "FEBUXOSTAT": 2.6376589170415925, "FENTANYL": 2.1596142784655523, "FIASP": 6.767579986124002, "FLUTICASONE": 1.3720232490178683, "FORSTEO": 0.5227417228684496, "FORXIGA": 0.684264271364976, "FYCOMPA": 1.3183833836428067, "GALAFOLD": 2.434036577458104, "GALVUS": 1.5279231023188915, "GENVOYA": 2.0275586377277617, "GLUCAGON": 3.338051756732825, "HARVONI": 0.528511131305157, "HIZENTRA": 0.8880921964510422, "HUMALOG": 3.754923231788025, "IBRANCE": 0.3880989300659381, "ICLUSIG": 0.8822840427282438, "INCRUSE": 1.2843647253084696, "INSULIN": 4.566462624161714, "ISENTRESS": 3.386867071096936, "JAKAVI": 1.7224380755464397, "JANUMET": 6.166761866160029, "JANUVIA": 4.329146970490279, "JARDIANCE": 0.6129843645863612, "KEPPRA": 2.19103524317312, "KISQALI": 0.7819778177248785, "LANTUS": 3.0798549617291253, "LATUDA": 4.8387584713696965, "LEVEMIR": 2.536381027493842, "LEVETIRACETAM": 0.5228768653403324, "LEVOFLOXACIN": 0.4420458646719165, "LIXIANA": 4.600057914450002, "LYNPARZA": 0.7188826358286354, "LYRICA": 0.3147512170942141, "LYUMJEV": 9.733286507377985, "MEKINIST": 1.037108622400309, "MELATONIN": 1.5353921930093015, "METHOTREXATE": 0.1545839850640142, "MICARDIS": 0.7279582184714151, "MIDAZOLAM": 0.855464721344453, "MIMPARA": 6.851611353012378, "MIXTARD": 4.966540947246091, "MULTAQ": 2.202025732545953, "NEULASTA": 14.208127611540537, "NEVANAC": 7.9308903828756705, "NEXAVAR": 0.1613953093459098, "NOT": 0.5297514758208409, "NOVORAPID": 13.282866946254314, "NOXAFIL": 1.3048635571282443, "NUCALA": 0.777652744530243, "OLANZAPINE": 0.4213103485246127, "OMALIZUMAB": 1.5427936046318218, "OMNITROPE": 9.245741986126196, "OPSUMIT": 0.2151157106364684, "OXYBUTYNIN": 1.2963524802638815, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12888.json
new file mode 100644
index 00000000000..af625d7ac14
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12888.json
@@ -0,0 +1 @@
+{"CANAKINUMAB": 39948.25834000792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12889.json
new file mode 100644
index 00000000000..476bb87ccad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12889.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 21.26085129117077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1289.json
index 9fde26cde50..8aeceaa4d7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1289.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1289.json
@@ -1 +1 @@
-{"null": 2.0174289351687524}
\ No newline at end of file
+{"null": 1.5473253498493524}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12890.json
new file mode 100644
index 00000000000..53dd183ce65
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12890.json
@@ -0,0 +1 @@
+{"ABATACEPT": 10.689411445373567, "ADALIMUMAB": 9.016356930992076, "ARAVA": 6.262315252331133, "CIMZIA": 20.77162435893641, "ENBREL": 8.214935787937405, "FENTANYL": 5.7910802021429415, "null": 0.4360613180751527}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12891.json
new file mode 100644
index 00000000000..c6490dabd28
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12891.json
@@ -0,0 +1 @@
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12892.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12892.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12893.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12893.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12894.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12894.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12895.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12895.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12896.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12896.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12897.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12897.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12898.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12898.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12899.json
new file mode 100644
index 00000000000..f3cabf6ee8b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12899.json
@@ -0,0 +1 @@
+{"null": 0.6321768676074653}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/129.json
index 040906b357f..60471d29d9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/129.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 62.7659728197267, "AZATHIOPRINE": 6.137959921782581, "BUDESONIDE": 10.937897834987767, "BUSILVEX": 81.29891484665166, "BUSULFAN": 193.1440571328875, "CANCIDAS": 8.887920002633583, "CELLCEPT": 6.2496369119336, "CICLOSPORIN": 105.31685171796516, "CYTARABINE": 3.587126836832636, "DEXAMETHASONE": 4.028276705264547, "DOXORUBICIN": 11.27876069501697, "GANCICLOVIR": 8.473399684785521, "JAKAVI": 2.976029861665217, "MELPHALAN": 83.38739046895434, "METHOTREXATE": 13.51308298186652, "MYCOPHENOLATE": 18.17143152520908, "RITUXIMAB": 1.75007828254617, "RUXOLITINIB": 10.048406242167546, "SOLIRIS": 2.478358234942793, "TACROLIMUS": 9.556973829554424, "TEPADINA": 465.04008749833, "THIOTEPA": 40.98962384468704}
\ No newline at end of file
+{"BUSULFAN": 14.09672103581935, "LACOSAMIDE": 86.28816720019404, "LEVETIRACETAM": 440.4716700362024, "null": 0.8732640691101635}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1290.json
index 73871b8aa99..cb2d777992e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1290.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1290.json
@@ -1 +1 @@
-{"COMIRNATY": 3.147472992979781, "ELLAONE": 58.53795787571606, "ESMYA": 22.96720578288431, "SPIKEVAX": 1.436558865127161, "null": 1.3557869074692075}
\ No newline at end of file
+{"null": 1.1844118477648815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12900.json
new file mode 100644
index 00000000000..8a2f441ad5f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12900.json
@@ -0,0 +1 @@
+{"null": 1.9394105009784244}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12901.json
new file mode 100644
index 00000000000..71720e3f819
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12901.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 34.38870391961016, "null": 1.9499670788388528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12902.json
new file mode 100644
index 00000000000..a3e387b8257
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12902.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 0.2633485759917027, "VFEND": 271.5953308578652, "VORICONAZOLE": 62.95058771245306, "null": 1.0255396544326014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12903.json
new file mode 100644
index 00000000000..87a40780baf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12903.json
@@ -0,0 +1 @@
+{"null": 0.8863141901861349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12904.json
new file mode 100644
index 00000000000..ec1932a9045
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12904.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1839465928018575, "null": 1.4245583456221265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12905.json
new file mode 100644
index 00000000000..973e056aed3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12905.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.088895958970045, "IRBESARTAN": 27.237514801319797, "NEXAVAR": 6.102032463806109, "OPTIMARK": 27.82084979076061, "VECTIBIX": 82.14570575782956, "null": 0.676191504204108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12906.json
new file mode 100644
index 00000000000..bcc6f4e5d25
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12906.json
@@ -0,0 +1 @@
+{"PUREGON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12907.json
new file mode 100644
index 00000000000..f4dd9af32bc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12907.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 9.901584925826766, "BUVIDAL": 74.95806986209539, "COMIRNATY": 0.7802323884522218, "CYMBALTA": 4.726662466709295, "SPIKEVAX": 0.296891443804749, "SUBOXONE": 9.518443367766004, "TOZINAMERAN": 0.9899020188593834, "VAXZEVRIA": 1.031182353129766, "null": 1.9768873188673275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12908.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12908.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12909.json
new file mode 100644
index 00000000000..c201bb7901f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12909.json
@@ -0,0 +1 @@
+{"null": 3.442185040714239}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1291.json
index fbe844491fd..dbfc85c1f21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1291.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1291.json
@@ -1 +1 @@
-{"CAPECITABINE": 15.766508143965282, "ELIQUIS": 2.585098252771314, "FORSTEO": 4.144944076315723, "IBRANCE": 2.4400004914514275, "MEPOLIZUMAB": 22.839437839806884, "null": 1.350543759709043}
\ No newline at end of file
+{"null": 1.409360948848984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12910.json
new file mode 100644
index 00000000000..3f3cbc22748
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12910.json
@@ -0,0 +1 @@
+{"null": 28.1021718249388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12911.json
new file mode 100644
index 00000000000..fa0c5e9bc0e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12911.json
@@ -0,0 +1 @@
+{"null": 8.66916440918874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12912.json
new file mode 100644
index 00000000000..0869defee7c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12912.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1613827506126781, "COSENTYX": 0.9257721897181456, "CYMBALTA": 0.4888729559566979, "DEXAMETHASONE": 1.6837450955280286, "ELIQUIS": 0.3148921157379216, "EXVIERA": 23.521585810174944, "KEPPRA": 0.5308885779199597, "NEXAVAR": 2.7508372151864373, "OCALIVA": 10.414216359918186, "PEGASYS": 0.6037657723745053, "REYATAZ": 9.993287100285988, "SAXENDA": 2.0406543872942104, "SPIKEVAX": 0.1656723325607055, "STIVARGA": 3.511508633704869, "SUTENT": 81.6430776976172, "TOZINAMERAN": 0.2177371650309698, "VAXZEVRIA": 0.2060513540161015, "VOTRIENT": 3.808115026102385, "null": 0.8323863596533807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12913.json
new file mode 100644
index 00000000000..f0401afe8dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12913.json
@@ -0,0 +1 @@
+{"null": 0.5234282361212452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12914.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12914.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12915.json
new file mode 100644
index 00000000000..7063dd2664a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12915.json
@@ -0,0 +1 @@
+{"null": 0.6431888240746095}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12916.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12916.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12917.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12917.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12918.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12918.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12919.json
new file mode 100644
index 00000000000..de6a8424e19
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12919.json
@@ -0,0 +1 @@
+{"JETREA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1292.json
index e9bfa757179..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1292.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1292.json
@@ -1 +1 @@
-{"null": 1.921723426875465}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12920.json
new file mode 100644
index 00000000000..3793fa36247
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12920.json
@@ -0,0 +1 @@
+{"JARDIANCE": 93.00475096510934, "null": 0.5138213095224082}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12921.json
new file mode 100644
index 00000000000..fe9fb53e246
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12921.json
@@ -0,0 +1 @@
+{"LANTUS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12922.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12922.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12923.json
new file mode 100644
index 00000000000..30380b6ee3a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12923.json
@@ -0,0 +1 @@
+{"null": 1.719128601799418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12924.json
new file mode 100644
index 00000000000..9289cf74da8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12924.json
@@ -0,0 +1 @@
+{"null": 0.4772793874135558}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12925.json
new file mode 100644
index 00000000000..59247de054d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/12925.json
@@ -0,0 +1 @@
+{"null": 0.9376157692801071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1293.json
index f488584e472..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1293.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1293.json
@@ -1 +1 @@
-{"null": 1.7436960170364368}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1294.json
index eb966fa5b3c..5ccdd20308d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1294.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1294.json
@@ -1 +1 @@
-{"COMIRNATY": 6.233782305272988, "SPIKEVAX": 2.0249198067576746}
\ No newline at end of file
+{"ARAVA": 4.605848588112912, "null": 1.121496548140921}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1295.json
index c286c64c6e6..473469b72a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1295.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1295.json
@@ -1 +1 @@
-{"CHAMPIX": 1.6293011228083516, "COMIRNATY": 3.351256566633026, "CYMBALTA": 1.058148162136435, "EPIVIR": 10.050274068551545, "FORSTEO": 1.8983292713020343, "INVEGA": 50.34546184779829, "KAFTRIO": 6.036611280745191, "OLANZAPINE": 1.6356935618068522, "ZYPREXA": 3.420498989317903, "null": 1.343027433749821}
\ No newline at end of file
+{"null": 0.6127986984377405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1296.json
index 0744c579cf1..4b093f92c4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1296.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1296.json
@@ -1 +1 @@
-{"COMIRNATY": 1.290646586481168, "KEPPRA": 4.431388638403933, "null": 2.509729990345664}
\ No newline at end of file
+{"REVESTIVE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1297.json
index cb574323171..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1297.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1297.json
@@ -1 +1 @@
-{"null": 2.079574660946283}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1298.json
index 6f61c5f0f02..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1298.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1298.json
@@ -1 +1 @@
-{"ELIQUIS": 7.623431057954024, "null": 1.5529276440854425}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1299.json
index 0f2fdd9d538..035e38537ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1299.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1299.json
@@ -1 +1 @@
-{"ELIQUIS": 8.581724377887467, "IBRANCE": 16.94664086586256}
\ No newline at end of file
+{"ORKAMBI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/13.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/13.json
index 02520c85835..c2afdbf7d9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/13.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/13.json
@@ -1 +1 @@
-{"null": 1.1793920263568098}
\ No newline at end of file
+{"null": 14.302888169257942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/130.json
index 07ac507dc4d..52e90714c4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/130.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 74.40462534909389, "BASILIXIMAB": 46.38427783947407, "BUSULFAN": 200.55528389491263, "CANCIDAS": 28.6298501178443, "CELLCEPT": 4.672818127119497, "CICLOSPORIN": 107.34010978057256, "CYTARABINE": 5.789035605391401, "MELPHALAN": 64.2556300606548, "METHOTREXATE": 6.581540307748151, "MYCOPHENOLATE": 29.80960152005947, "THIOTEPA": 162.54282149464166}
\ No newline at end of file
+{"null": 0.4920994718959467}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1300.json
index 27bc0578be4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1300.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1300.json
@@ -1 +1 @@
-{"null": 2.9400792309141184}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1301.json
index bea25ca51a4..4cd9ceca41f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1301.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1301.json
@@ -1 +1 @@
-{"COMIRNATY": 1.860959157267393, "null": 1.196956730246285}
\ No newline at end of file
+{"null": 1.071228140334486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1302.json
index d7eeb82f627..f3280256e1f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1302.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1302.json
@@ -1 +1 @@
-{"COMIRNATY": 6.41050713918413, "SPIKEVAX": 1.5696494915116426, "TOZINAMERAN": 1.2617728890922824}
\ No newline at end of file
+{"VICTOZA": 39.728175712834606, "null": 1.001406191400178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1303.json
index 5ed686d3417..778f4aad1f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1303.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1303.json
@@ -1 +1 @@
-{"null": 1.0067924667284014}
\ No newline at end of file
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1304.json
index 97fa1a826f2..1197800c0d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1304.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1304.json
@@ -1 +1 @@
-{"null": 2.8888362465479496}
\ No newline at end of file
+{"METHOTREXATE": 39.30815394333663, "null": 0.8386737392886748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1305.json
index 00346b872e8..5c1122093b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1305.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1305.json
@@ -1 +1 @@
-{"AFINITOR": 1.1048209077495004, "APIDRA": 2.942529427564948, "CICLOSPORIN": 1.8907226954075544, "DOCETAXEL": 2.3004530437062853, "EVISTA": 9.097949359735118, "FASLODEX": 3.742652053496448, "FORSTEO": 1.5199691157585986, "GARDASIL": 1.119217609445151, "IBRANCE": 1.395727280983636, "KISQALI": 5.230897797688006, "METHOTREXATE": 1.8717401066595865, "PEGASYS": 1.7773045074949765, "RIBOCICLIB": 36.2931240431416, "SIMPONI": 1.5529323080894994, "STELARA": 2.617489181329035, "TOZINAMERAN": 2.4860751803810763, "XELJANZ": 1.8656162927313813, "XOLAIR": 3.008872779811941, "ZOSTAVAX": 1.94668513881119, "ZYPREXA": 1.4270904943886304, "null": 1.2670456946964808}
\ No newline at end of file
+{"KALETRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1306.json
index 8673b0a522e..d2874698ab7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1306.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1306.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4869575504190364, "null": 1.2060823558289395}
\ No newline at end of file
+{"BYETTA": 72.36487152243265, "null": 0.68141364394783}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1307.json
index 6b281c67add..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1307.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1307.json
@@ -1 +1 @@
-{"null": 5.083191106119852}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1308.json
index cad8e0f94cd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1308.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1308.json
@@ -1 +1 @@
-{"FORSTEO": 6.69696218509038, "MEPOLIZUMAB": 13.89880765352929, "STELARA": 8.776848910864139, "XOLAIR": 7.519044519746774}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1309.json
index 47e9419752d..416b984744d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1309.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1309.json
@@ -1 +1 @@
-{"COMIRNATY": 5.882816660105015, "SPIKEVAX": 1.2274488796128933}
\ No newline at end of file
+{"NEXAVAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/131.json
index 06e461f1b82..462456f5d40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/131.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 24.44637553113779, "BUSULFAN": 182.15539990892736, "CICLOSPORIN": 100.81155542103345, "CYTARABINE": 11.880416269822566, "MYCOPHENOLATE": 58.69114474023494}
\ No newline at end of file
+{"AMIKACIN": 95.3788230832942, "CASPOFUNGIN": 47.24532103793901, "CICLOSPORIN": 17.025623278808453, "TIGECYCLINE": 277.80555008510726, "null": 0.7437169986173532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1310.json
index f2590f16a5d..a282d30f932 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1310.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1310.json
@@ -1 +1 @@
-{"IBRANCE": 17.298049151282374, "MEPOLIZUMAB": 24.34012161284911, "null": 1.074026062456546}
\ No newline at end of file
+{"ACLIDINIUM": 11.92723072463793, "ADENURIC": 13.094574738344413, "ALENDRONATE": 254.50821919849128, "APIXABAN": 21.674218680067717, "ATRIPLA": 0.2281654563608994, "BIKTARVY": 15.761002625669224, "BUPIVACAINE": 7.873169885119372, "BYDUREON": 3.1059495199926874, "BYETTA": 10.812551405395268, "CARBIDOPA": 14.109993673882244, "CLOPIDOGREL": 1.500388778259815, "COMIRNATY": 0.0728698759687564, "DARUNAVIR": 23.905324197867053, "ELIQUIS": 3.544880307161336, "ENTRESTO": 1.2473937069145522, "FORXIGA": 3.496260949525925, "ICLUSIG": 4.691031022613292, "JANUMET": 13.330587295727218, "JANUVIA": 11.983323802685156, "JARDIANCE": 2.628309522925701, "KALETRA": 11.598366996517209, "KEPPRA": 0.7940314296341193, "KEYTRUDA": 0.5771714256817271, "LANTUS": 0.5364256360116076, "OLANZAPINE": 0.973750733285234, "SPIKEVAX": 0.078210860137526, "SUTENT": 0.4468009308100529, "TASIGNA": 2.054741247569726, "TOVIAZ": 24.31190126888239, "VIAGRA": 8.661753688545563, "ZOSTAVAX": 17.209291136147144, "ZYPREXA": 1.7589993821552494, "null": 1.0194883498781}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1311.json
index afe2bdb1201..8d908d42834 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1311.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1311.json
@@ -1 +1 @@
-{"AIMOVIG": 1.9943959386481849, "CAPECITABINE": 1.6212855489038005, "COMIRNATY": 4.408366062322136, "ELLAONE": 21.78240385878443, "ESMYA": 2.988441351431604, "EVISTA": 1.116212572837334, "EVRA": 6.820687666695131, "FASLODEX": 1.0224477106547942, "KAFTRIO": 2.49146576847176, "LYRICA": 1.0003540243478874, "OVITRELLE": 20.400663249231133, "SPIKEVAX": 1.801544697296928, "TOZINAMERAN": 2.886934704916904}
\ No newline at end of file
+{"null": 1.8606103525598985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1312.json
index bb660b9f9da..2d438d4ec7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1312.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1312.json
@@ -1 +1 @@
-{"ARAVA": 34.65529341395296}
\ No newline at end of file
+{"null": 1.6512278057843617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1313.json
index ae8a012b8d4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1313.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1313.json
@@ -1 +1 @@
-{"null": 2.80330718380949}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1314.json
index 88ff9a74ecd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1314.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1314.json
@@ -1 +1 @@
-{"COMIRNATY": 5.213203589977337, "ELLAONE": 24.15111959547352, "EVISTA": 4.472314358611604, "SPIKEVAX": 1.5546114187587377, "TOZINAMERAN": 3.076130311156124}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1315.json
index 5ac57a33fc5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1315.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1315.json
@@ -1 +1 @@
-{"AIMOVIG": 1.7241228340403478, "COMIRNATY": 3.996406142481152, "ELLAONE": 35.05443348359041, "SPIKEVAX": 1.5389202493572345, "TOZINAMERAN": 1.3061874111835745, "null": 1.1514071582798877}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1316.json
index 10ade746ec7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1316.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1316.json
@@ -1 +1 @@
-{"null": 8.782520890325227}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1317.json
index 5b7be874ddc..24e60349b59 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1317.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1317.json
@@ -1 +1 @@
-{"MMRVAXPRO": 51.02515718285372, "XYREM": 93.9842839999692, "null": 1.1445222186498851}
\ No newline at end of file
+{"null": 2.822612585487926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1318.json
index 0111953d6ba..c440f5cc6e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1318.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1318.json
@@ -1 +1 @@
-{"CELECOXIB": 25.438864669135505, "CYMBALTA": 1.3575983995159169, "GARDASIL": 1.9725477293063245, "JARDIANCE": 2.700179738509093, "KALETRA": 7.010672306491818, "PEGASYS": 1.314842757087364, "SAXENDA": 10.363382417658302, "SUTENT": 1.5713489312969893, "TRULICITY": 13.46262591544766, "null": 1.6057770935739093}
\ No newline at end of file
+{"null": 3.51233967253537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1319.json
index 7e7683d847e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1319.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1319.json
@@ -1 +1 @@
-{"COMIRNATY": 1.044700417152018, "null": 1.496475979729068}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/132.json
index 332ce562ed2..2d438d4ec7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/132.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 31.71298872039715, "ASPARAGINASE": 5.158804254737412, "AZACITIDINE": 11.475916850729137, "BUDESONIDE": 1.6838032245151562, "BUSILVEX": 118.4034805952871, "BUSULFAN": 311.7448682611912, "CICLOSPORIN": 104.30356876756905, "CYTARABINE": 7.730972200496694, "JAKAVI": 10.98061870651816, "KYMRIAH": 6.362211731247109, "METHOTREXATE": 10.958466725344543, "MYCOPHENOLATE": 35.37857387935901, "THIOTEPA": 191.7586418440809}
\ No newline at end of file
+{"null": 1.6512278057843617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1320.json
index a30d039b963..04c99124262 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1320.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1320.json
@@ -1 +1 @@
-{"ACLIDINIUM": 69.76869441116006, "AFINITOR": 1.2590940212060582, "ARAVA": 1.7378066485815904, "AZATHIOPRINE": 2.860074264859325, "BUDESONIDE": 37.50732027537634, "CLOPIDOGREL": 1.501796072571039, "DEXAMETHASONE": 1.6228717950957765, "DUAKLIR": 150.2917806829923, "ENTRESTO": 3.007565562611109, "ESOMEPRAZOLE": 7.647203144882404, "EXJADE": 3.128864064825811, "LEVOFLOXACIN": 2.6193228652632774, "MEPOLIZUMAB": 13.195933817245791, "NUCALA": 73.47428160643537, "OMALIZUMAB": 7.964970962215161, "PANTOPRAZOLE": 8.986749377137475, "PREGABALIN": 8.585482710437963, "ROTATEQ": 3.617247116940925, "XOLAIR": 5.307364265968516, "null": 1.0739462691894297}
\ No newline at end of file
+{"INSULIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1321.json
index b8b6bafa867..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1321.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1321.json
@@ -1 +1 @@
-{"null": 2.1222868188317268}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1322.json
index e8728a8fac0..ced89fda5cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1322.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1322.json
@@ -1 +1 @@
-{"null": 1.724603477394154}
\ No newline at end of file
+{"HEPSERA": 289.51718883776385, "null": 0.9142753825506328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1323.json
index 25e4f0663c0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1323.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1323.json
@@ -1 +1 @@
-{"ABILIFY": 79.98185158090354, "CIMZIA": 6.121922775596226, "DEXAMETHASONE": 9.202093282503254, "GARDASIL": 11.104111477924382, "null": 1.5757303374695784}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1324.json
index 8fd14eb7a59..15dd5b48b03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1324.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1324.json
@@ -1 +1 @@
-{"CHAMPIX": 36.41218226056184, "null": 1.7609822260584742}
\ No newline at end of file
+{"HEPSERA": 323.52143498466376, "null": 0.7845271062493032}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1325.json
index 9211466a762..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1325.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1325.json
@@ -1 +1 @@
-{"null": 1.4123157093751173}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1326.json
index e73a7021d31..79e7f56aba5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1326.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1326.json
@@ -1 +1 @@
-{"null": 2.0210695270957983}
\ No newline at end of file
+{"COMIRNATY": 0.1190483679480864, "GARDASIL": 6.578791146617865, "null": 1.241200427390822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1327.json
index 04f83c0802b..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1327.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1327.json
@@ -1 +1 @@
-{"null": 2.119843710264686}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1328.json
index 85964a0a58d..14806133b87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1328.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1328.json
@@ -1 +1 @@
-{"null": 1.367162783502541}
\ No newline at end of file
+{"null": 1.905017702804813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1329.json
index 1c6b45b48ea..471d4a2b152 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1329.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1329.json
@@ -1 +1 @@
-{"CELLCEPT": 19.87842975688542, "FORSTEO": 9.34636783690194}
\ No newline at end of file
+{"OLANZAPINE": 12.690089928424156, "null": 5.626567333517026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/133.json
index 885cd7e549a..ee9fd85d07a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/133.json
@@ -1 +1 @@
-{"null": 1.3429555258382595}
\ No newline at end of file
+{"null": 1.2468637412963794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1330.json
index 79a0bd92a74..731a739207a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1330.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1330.json
@@ -1 +1 @@
-{"CELLCEPT": 6.214608289540192, "PANTOPRAZOLE": 47.23891419686456, "XELJANZ": 4.440277029508794, "null": 1.2693845900021177}
\ No newline at end of file
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1331.json
index 9197559eb2a..1c93d877847 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1331.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1331.json
@@ -1 +1 @@
-{"ELIQUIS": 6.169749691736408, "TICAGRELOR": 95.99923570525895}
\ No newline at end of file
+{"null": 1.174616373878293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1332.json
index 3c02cbb4e32..b1fbc5979b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1332.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1332.json
@@ -1 +1 @@
-{"BUDESONIDE": 3.243989488013666, "CEFUROXIME": 729.1664017992144, "DOVATO": 265.38219228543363, "ENTRESTO": 7.795532045927324, "GARDASIL": 2.169827093298637, "IBUPROFEN": 5.416079253761132, "LAMIVUDINE": 32.69532221930547, "MEPOLIZUMAB": 6.580119315673018, "NUCALA": 6.511848256408243, "PEGASYS": 1.2757144545749768, "SYNAGIS": 16.734990816283222, "ZOSTAVAX": 3.1221362777724835, "null": 1.3238313348074815}
\ No newline at end of file
+{"null": 8.257856272687105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1333.json
index 1ffebc51a08..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1333.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1333.json
@@ -1 +1 @@
-{"null": 1.359417735449565}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1334.json
index 5c0667b3cd1..ccad88b880c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1334.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1334.json
@@ -1 +1 @@
-{"null": 1.9860002587710184}
\ No newline at end of file
+{"ALIMTA": 8.5834952554688, "AMINOSALICYLIC": 6.118621922607735, "CELLCEPT": 8.352083319475836, "COMIRNATY": 0.0923465561115686, "DOCETAXEL": 24.457864657019265, "DOXORUBICIN": 23.31936433438412, "JANUMET": 3.872580174074093, "MABTHERA": 13.29593638447238, "METHOTREXATE": 2.3899238970500445, "PLAVIX": 1.6014159520157267, "RITUXIMAB": 23.145263239513, "SUTENT": 0.8381984411516216, "null": 1.4722621280486263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1335.json
index e4b2652f84c..2871d74a1c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1335.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1335.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"null": 1.5326799606612636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1336.json
index 1dcb19b3a80..4eae046db3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1336.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1336.json
@@ -1 +1 @@
-{"ACLIDINIUM": 209.5070872558104, "BENRALIZUMAB": 60.54757752079427, "GLYCOPYRRONIUM": 46.3832179390269, "KEPPRA": 2.347639169368977, "MEPOLIZUMAB": 97.43421844921116, "NUCALA": 18.436061770516137, "OMALIZUMAB": 7.328313837359365, "ONCASPAR": 33.35428060941311, "PANTOPRAZOLE": 27.16930056752932, "null": 1.0665280075461026}
\ No newline at end of file
+{"THALIDOMIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1337.json
index 0c417fc9f9f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1337.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1337.json
@@ -1 +1 @@
-{"null": 2.216280710420783}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1338.json
index 243ab31c10a..49b1b7b1a37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1338.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1338.json
@@ -1 +1 @@
-{"ALENDRONATE": 874.8399510733706, "APIXABAN": 87.76396177459479, "BENRALIZUMAB": 472.9529590113754, "BUDESONIDE": 11.93272844282886, "ELIQUIS": 4.551385417220312, "FASENRA": 11.6796909652904, "KAFTRIO": 21.185854291791117, "MEPOLIZUMAB": 11.529871446452535, "NUCALA": 11.75302990976973, "OMALIZUMAB": 8.745385729991323, "SPINRAZA": 60.50588926688396, "XOLAIR": 3.392692037356375}
\ No newline at end of file
+{"null": 0.5469400070995776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1339.json
index f3db4bfa5cf..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1339.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1339.json
@@ -1 +1 @@
-{"ACLIDINIUM": 160.32214726127918, "ALENDRONATE": 1041.1970068847506, "APIXABAN": 96.09142190130868, "BENRALIZUMAB": 619.6235707617701, "DEXAMETHASONE": 12.038923102175795, "ELIQUIS": 5.157981976522295, "IBUPROFEN": 6.947162610014593, "MEPOLIZUMAB": 7.4445153590315325, "NUCALA": 27.33815615126919}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/134.json
index 21498e13854..7d105ddfb5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/134.json
@@ -1 +1 @@
-{"null": 1.5410781034375796}
\ No newline at end of file
+{"ABILIFY": 0.3846963983936308, "AFINITOR": 3.125640769979904, "AIMOVIG": 1.3448150507183048, "ALEMTUZUMAB": 1.0596415298345905, "ARAVA": 0.2899136616816122, "AUBAGIO": 1.839615192664504, "AVASTIN": 1.1679633971522176, "BELIMUMAB": 4.987092114352351, "BENLYSTA": 1.3283335045602211, "BEVACIZUMAB": 0.8266008924579757, "BIKTARVY": 0.8369231597785901, "BRAFTOVI": 3.6249476135339824, "BRINTELLIX": 2.73425575782792, "BYDUREON": 0.5001865008021439, "CABOMETYX": 1.065591117125581, "CAPRELSA": 27.746559207382862, "CARIPRAZINE": 18.9497138153202, "CELLCEPT": 3.007191735212182, "CHAMPIX": 1.3552444324545447, "CICLOSPORIN": 0.8194577772720743, "CIMZIA": 0.6721447069469385, "COAPROVEL": 1.5615375853042424, "COMIRNATY": 0.7119001532896765, "COSENTYX": 2.2420718819795584, "COTELLIC": 3.555496705658454, "CYMBALTA": 0.5696294095994757, "DACLIZUMAB": 135.4315883148184, "DASATINIB": 6.5464473532426135, "DULOXETINE": 1.4812679361628118, "ELIQUIS": 0.4448015293253163, "ELLAONE": 8.076129688567814, "ENBREL": 0.4813537949702283, "ENTRESTO": 0.7597177607216499, "ENTYVIO": 4.772925638971505, "ERBITUX": 2.614319999142741, "ESMYA": 5.843786208510593, "ESOMEPRAZOLE": 1.918458341065753, "EVRA": 3.0727292852334545, "FAMPYRA": 1.3823303037093004, "FASENRA": 0.6469216501519144, "FORSTEO": 0.5809321073097832, "FORXIGA": 0.503249208291417, "GARDASIL": 4.271315468787484, "GENVOYA": 3.6600306136655134, "HERCEPTIN": 1.8719141266086656, "HUMALOG": 0.2288231170089129, "HUMIRA": 3.0280996879267668, "IBRANCE": 0.6225050228713153, "IBUPROFEN": 0.5149442941338156, "INCIVO": 1.5207335678441416, "INFLIXIMAB": 3.6345063142172536, "INLYTA": 0.5235700999826882, "IRESSA": 8.154198755526084, "JAKAVI": 0.9544483574642426, "JANUMET": 0.4417164715933928, "JARDIANCE": 0.72288498734793, "KAFTRIO": 26.7752188845848, "KALETRA": 0.7139005376618142, "KALYDECO": 4.158813117213652, "KEPPRA": 1.3804392040656324, "KESIMPTA": 3.275654601448426, "KEYTRUDA": 0.1905265957583624, "LANTUS": 0.2139083106047298, "LEFLUNOMIDE": 3.6671192528914376, "MAVENCLAD": 2.630595617997154, "MEKINIST": 3.863900678819783, "METHOTREXATE": 1.1084829607154814, "MMRVAXPRO": 0.3981880933086514, "MODERNA": 0.3601402217851895, "NEXAVAR": 1.0836935422159812, "NUCALA": 0.4005250395171388, "OLANZAPINE": 0.3214400533677, "OMALIZUMAB": 1.8275673908541503, "PEGASYS": 0.5156206012850347, "PLEGRIDY": 0.9982642131069552, "RAPAMUNE": 2.4818370161400414, "RELVAR": 1.3832936514797578, "RINVOQ": 48.28799154725069, "RITUXIMAB": 0.690197182869954, "ROACTEMRA": 0.4512688598449348, "SAXENDA": 0.8895126180543889, "SHINGRIX": 1.0020561099864436, "SIMPONI": 0.7515930211486086, "SKYRIZI": 2.971094238981685, "SOMATROPIN": 3.2689167459726987, "SPIKEVAX": 0.4828358525250114, "SPRYCEL": 2.893460566737926, "STELARA": 1.9713961106187083, "SUBOXONE": 0.310631598374589, "SUTENT": 1.515267385262515, "TAGRISSO": 3.9817893001292526, "TASIGNA": 1.1208748937016246, "TESTOSTERONE": 9.440369199313349, "TOZINAMERAN": 0.5234224268605089, "TREMFYA": 1.403359263316362, "UPADACITINIB": 118.97330193862942, "VAXZEVRIA": 0.2330606967510821, "VECTIBIX": 7.180639476509835, "XELJANZ": 4.822679631666355, "XOLAIR": 1.0326433266366208, "ZELBORAF": 5.960635758626046, "ZOSTAVAX": 0.7023391183204971, "ZYPREXA": 0.4536054565203419, "null": 1.1966914701254971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1340.json
index 1f0535eec81..b8aea1b97e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1340.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1340.json
@@ -1 +1 @@
-{"ACLIDINIUM": 141.1567129153049, "ADALIMUMAB": 7.462814001381392, "ADCIRCA": 7.228203542577359, "ALENDRONATE": 187.49994281058835, "AMIKACIN": 10.289576518451682, "ANORO": 8.993173748749316, "APIXABAN": 17.766061986784205, "ARANESP": 10.711735328415182, "ARAVA": 1.0515326540624197, "AVAMYS": 25.262507651313296, "BEDAQUILINE": 10.230507396783027, "BUDESONIDE": 20.224923658887302, "BUSULFAN": 11.1842811433471, "CANAGLIFLOZIN": 39.18518846424416, "CELLCEPT": 5.704708313311393, "CICLOSPORIN": 1.5186059913699774, "DUAKLIR": 152.05915273796617, "DULOXETINE": 3.066395493170857, "ELIQUIS": 1.2999544728080912, "FASENRA": 3.1338368606986813, "FASLODEX": 2.558023310148499, "FLUTICASONE": 17.056452314801216, "GANCICLOVIR": 6.120267609181379, "HIZENTRA": 3.532536809394802, "HUMIRA": 1.215748672773187, "HYDROCORTISONE": 10.235221294369191, "INVOKANA": 9.1888848388842, "LEVOFLOXACIN": 1.179467432365376, "MEPOLIZUMAB": 8.809644625387556, "NUCALA": 13.944320408380218, "OCEAN": 179.1479124851229, "OMALIZUMAB": 12.98511763686602, "ORKAMBI": 13.967229476221178, "PANTOPRAZOLE": 2.5151533880274, "PEMBROLIZUMAB": 2.298979924993493, "PIRFENIDONE": 21.00905712958486, "RITUXIMAB": 2.3817919395280085, "TRELEGY": 3.840513859991636, "XELJANZ": 1.300223423829503, "XOLAIR": 2.431348778599655}
\ No newline at end of file
+{"IBUPROFEN": 61.41582330443742, "null": 1.3878501484203587}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1341.json
index a26ac98846d..522ee8d28b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1341.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1341.json
@@ -1 +1 @@
-{"ACLIDINIUM": 16.184627751824355, "CELLCEPT": 3.08275078665354, "HEMANGIOL": 88.99038388210653, "INFANRIX": 14.631801249887712, "LEVETIRACETAM": 2.2402039333998998, "MENVEO": 52.96407928467741, "MEPOLIZUMAB": 2.0523245159007684, "PEGINTRON": 1.3443360215956377, "ROTATEQ": 11.8543894487794, "SIMPONI": 1.6788450489484603, "SPINRAZA": 21.283858879245017, "STELARA": 1.0595462341407096, "SYNAGIS": 795.855106221385, "SYNFLORIX": 779.166294388646}
\ No newline at end of file
+{"BYETTA": 136.7899781858648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1342.json
index 88fadf7fbb9..57930e02946 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1342.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1342.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 153.73646169965403, "CICLOSPORIN": 31.003287276204}
\ No newline at end of file
+{"BYETTA": 37.41705141092123, "JANUVIA": 9.089296311098654, "null": 1.1075505433377764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1343.json
index 59462d44194..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1343.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1343.json
@@ -1 +1 @@
-{"ABATACEPT": 1.3739431493298595, "ACLASTA": 6.872485800774938, "ADCIRCA": 1.4153989691470992, "ADEMPAS": 1.8860180567576177, "AIMOVIG": 1.36020604428305, "AMIKACIN": 1.186049198753745, "AMINOSALICYLIC": 1.1244204982889383, "ANAKINRA": 1.173519906051504, "ANORO": 2.214297550283463, "APIDRA": 1.276797042757572, "AUBAGIO": 1.5990546426143328, "BELIMUMAB": 4.36990534305016, "BENLYSTA": 3.955046991806376, "BEVESPI": 14.135005294474642, "BIKTARVY": 2.0710222520168773, "BUDESONIDE": 2.2416119731510604, "BYDUREON": 1.5242725848945655, "CELECOXIB": 5.018177366407232, "CELLCEPT": 1.0762286027399628, "CIMZIA": 2.4855468498444586, "CLOPIDOGREL": 2.985298901728321, "COSENTYX": 2.571864779374616, "DALIRESP": 15.328287056032352, "DARZALEX": 1.2464881897987703, "DUPIXENT": 2.687965300865257, "ELIQUIS": 1.009908036798722, "ENBREL": 1.6895745005353515, "ENTRESTO": 1.1203593471316602, "ENTYVIO": 1.6770946393406632, "ESBRIET": 3.724276470447661, "ESOMEPRAZOLE": 1.5816724283422012, "ETANERCEPT": 3.1556564677496084, "EVISTA": 3.50988967534229, "EXFORGE": 1.267364277938425, "FASENRA": 3.236094928854714, "FIRDAPSE": 1.196767944887143, "FLUTICASONE": 12.34759718772734, "FORSTEO": 2.3143560612293226, "GLYCOPYRRONIUM": 2.813362071427512, "HIZENTRA": 7.538495760177081, "HUMIRA": 1.6998543209056935, "HYQVIA": 5.372261402599774, "IBRANCE": 1.8974204310019207, "INCIVO": 1.0438060305718384, "INCRUSE": 11.783268542761968, "INFANRIX": 4.793074176553232, "INFLECTRA": 5.665876066326844, "INFLIXIMAB": 1.2287871174797431, "INTRONA": 2.483175165673872, "IRON": 1.5398192550603322, "JANUVIA": 1.4257408688932571, "KESIMPTA": 2.347188477899661, "KYPROLIS": 1.954052478396343, "LANTUS": 1.0358773470566396, "MABTHERA": 1.5067152191906603, "MELATONIN": 1.1233895730833587, "MENVEO": 1.1324390933224695, "MEPOLIZUMAB": 4.066870378386263, "METHOTREXATE": 3.2512474815829533, "NAGLAZYME": 2.2190030684039117, "NORVIR": 1.2144438760201164, "NOT": 1.17562514784847, "NUCALA": 4.293013463825864, "OMALIZUMAB": 9.035773133460706, "ONGLYZA": 4.138791805920363, "OPSUMIT": 2.846184472045227, "ORENCIA": 6.544003010432597, "PANTOPRAZOLE": 3.1280184967955167, "PEGASYS": 1.7031026619467329, "PEGFILGRASTIM": 4.748375636996808, "PREVENAR": 1.4533795262536875, "PRIVIGEN": 1.142868239403267, "RAPAMUNE": 1.5802435349666166, "RELVAR": 4.115848754047945, "REMICADE": 2.639988332263864, "REVATIO": 3.490819053410932, "REVLIMID": 1.7808988863517854, "RINVOQ": 1.773406802152432, "RITUXIMAB": 1.6145680655587653, "ROACTEMRA": 2.9870738475352554, "ROTATEQ": 2.0554792476108785, "SIMPONI": 3.1610697821388025, "SPINRAZA": 3.549074768555447, "SPRYCEL": 1.2129430528930718, "STELARA": 2.15648258790678, "SYNAGIS": 11.508968038123813, "SYNFLORIX": 12.84332727274147, "TAMIFLU": 1.4687328379458953, "THALIDOMIDE": 1.0125552945051093, "TRACLEER": 2.368802221145326, "TRELEGY": 5.042637806137165, "TREMFYA": 2.7072940151323417, "TWINRIX": 1.1081413074606137, "VELCADE": 3.929137749055732, "VELTASSA": 1.8127509331795184, "VICTOZA": 1.0988357842861454, "XARELTO": 1.497797445132689, "XELJANZ": 5.287331104733708, "XOLAIR": 5.29452505358948, "XYREM": 2.745425383566882, "ZOMETA": 4.231971282776687, "ZOSTAVAX": 3.839916759821718, "ZYPREXA": 1.6366032470019285, "null": 1.420669303542253}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1344.json
index a0cadb43713..c0a5e9f5891 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1344.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1344.json
@@ -1 +1 @@
-{"BUDESONIDE": 23.353372908367465}
\ No newline at end of file
+{"JANUMET": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1345.json
index fa9c468c781..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1345.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1345.json
@@ -1 +1 @@
-{"ARAVA": 1.231510015641124, "BEDAQUILINE": 13.593554172192004, "ENBREL": 14.59417765144482, "IBUPROFEN": 3.597295329366199, "INSULIN": 12.578460965860348, "ISENTRESS": 20.98660208660462, "MEPOLIZUMAB": 4.891488166384924, "XOLAIR": 3.5212798120886037, "ZOSTAVAX": 6.110821475577046, "null": 1.5331656928091555}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1346.json
index 03b778baaf1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1346.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1346.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1347.json
index e6c0c6283e7..4279a621790 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1347.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1347.json
@@ -1 +1 @@
-{"MIDAZOLAM": 116.80149055447076, "null": 1.4712875473048062}
\ No newline at end of file
+{"ADALIMUMAB": 1.3392431540213834, "BYETTA": 38.51974539525071, "JANUMET": 31.07574086100994, "JANUVIA": 45.911639727923706, "null": 0.5734632923081902}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1348.json
index 82fe5841fc7..722ab187262 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1348.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1348.json
@@ -1 +1 @@
-{"null": 2.4815607600334006}
\ No newline at end of file
+{"BYETTA": 213.21945798769596, "JANUMET": 121.47132309481135, "JANUVIA": 207.5945946224801, "null": 0.0617641155455241}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1349.json
index 90ea7f8e653..68700a7d483 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1349.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1349.json
@@ -1 +1 @@
-{"BEDAQUILINE": 340.6205052791107}
\ No newline at end of file
+{"BYETTA": 6.564460759168819, "CICLOSPORIN": 2.177781322407572, "COMIRNATY": 0.045733541416325, "ESOMEPRAZOLE": 14.206758430730549, "JANUMET": 7.966826935465017, "JANUVIA": 10.065711819156355, "NEXAVAR": 3.1322955378131527, "SAXENDA": 15.290520358307775, "SUTENT": 1.1931208623395129, "XELJANZ": 1.8675290674179892, "null": 0.927340169860996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/135.json
index 6b2451b97d9..5c286b47d4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/135.json
@@ -1 +1 @@
-{"ALLI": 85.13577901866176, "AVASTIN": 1.1590975607415617, "AZATHIOPRINE": 2.640490827396351, "BARACLUDE": 8.85580735725713, "BEVACIZUMAB": 1.730760014181858, "BUSULFAN": 2.780124815509895, "CANCIDAS": 3.8503781547884985, "CYTARABINE": 1.6436637464135129, "DOXORUBICIN": 7.77583781712053, "DULOXETINE": 2.0614405500584096, "ENOXAPARIN": 2.580484724187375, "ENTECAVIR": 10.783547155231188, "EXJADE": 2.6364694038824537, "EXVIERA": 12.357646321432814, "FASLODEX": 2.5503264582655567, "FEBUXOSTAT": 7.108204797090248, "FENTANYL": 2.4535375489450595, "HARVONI": 2.697762741304837, "IBUPROFEN": 5.215297166348974, "KALETRA": 3.1796066045665903, "KEPPRA": 1.9234925418550013, "LACOSAMIDE": 4.500674491304552, "LAMIVUDINE": 11.273679665831851, "LEVETIRACETAM": 4.581103047247436, "LEVOFLOXACIN": 1.9955736433087496, "LOPINAVIR": 6.956339370450681, "MERCAPTOPURINE": 7.297124029268871, "METHOTREXATE": 1.2884752283128496, "MULTAQ": 5.140314491514364, "NEXAVAR": 3.21338627833468, "OLANZAPINE": 1.9097862927161768, "OLYSIO": 8.180619852071928, "ONCASPAR": 4.943831422580731, "PANTOPRAZOLE": 2.568373389376927, "PEGASYS": 1.169510301376432, "PEGINTRON": 1.2690740249727794, "RITUXIMAB": 6.380704945802501, "STIVARGA": 3.914022727578105, "SUNITINIB": 16.54972415045368, "SUTENT": 1.4858028675052712, "TAMIFLU": 3.425741380328815, "VFEND": 1.688609963546209, "VIRAMUNE": 18.76939921792588, "VORICONAZOLE": 2.5856632098605936, "VOTRIENT": 1.6348673855052955, "null": 2.3629281803631894}
\ No newline at end of file
+{"COMIRNATY": 0.694887048315681, "TOZINAMERAN": 2.4786181032861507, "null": 0.7428884905213126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1350.json
index 024afc0bc95..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1350.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1350.json
@@ -1 +1 @@
-{"null": 1.170974189443891}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1351.json
index 21d56489ff0..8940e9a4b84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1351.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1351.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 17.595827731929738, "AMIKACIN": 6.186924017394556, "ANIDULAFUNGIN": 62.51483531482919, "ASPARAGINASE": 82.87104268526888, "AXICABTAGENE": 37.950786354948434, "AZACITIDINE": 9.467144769669227, "AZATHIOPRINE": 3.188113090439413, "BASILIXIMAB": 21.782374444423755, "BORTEZOMIB": 10.512663891943696, "BUDESONIDE": 2.845877586195064, "BUSILVEX": 26.42179859007554, "BUSULFAN": 27.417968481722333, "CANCIDAS": 43.34668494295642, "CARMUSTINE": 16.246830411481817, "CASPOFUNGIN": 56.8478223562099, "CELLCEPT": 12.89187524762836, "CICLOSPORIN": 18.21929512446778, "CLADRIBINE": 25.96114587225858, "CYTARABINE": 15.747438688597022, "DEXAMETHASONE": 12.308115489229042, "DOXORUBICIN": 6.8681386893973855, "EMEND": 12.45973788943276, "FASENRA": 2.8358618755173035, "FILGRASTIM": 10.11119033701555, "GANCICLOVIR": 18.756910583858662, "IBRUTINIB": 20.694792117955508, "JAKAVI": 3.0768655645493865, "LEVOFLOXACIN": 1.1826108468841878, "METHOTREXATE": 2.549755574728489, "MYCOPHENOLATE": 26.929603193258327, "NOXAFIL": 38.15860262220375, "OPDIVO": 2.852820722390136, "PEGINTERFERON": 1.8348054042910455, "POSACONAZOLE": 13.653872966793005, "RITUXIMAB": 4.476486025026864, "RUXOLITINIB": 12.569243110210758, "SOLIRIS": 2.0081406932870385, "TACROLIMUS": 15.253063593946726, "VEKLURY": 12.41388475154058, "VFEND": 28.842559591859, "VORICONAZOLE": 56.17052401359245}
\ No newline at end of file
+{"null": 0.4889940080088393}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1352.json
index 341c29b7972..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1352.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1352.json
@@ -1 +1 @@
-{"ACLIDINIUM": 72.1848462799333, "APIXABAN": 26.04438636805492, "BUDESONIDE": 153.45661151596155, "MEPOLIZUMAB": 15.12851016024404, "NUCALA": 35.292782774382566, "OMALIZUMAB": 59.39389636963968, "ORKAMBI": 84.25134927806295, "XOLAIR": 7.645767157499886}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1353.json
index 925984eb1a5..45e36c777f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1353.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1353.json
@@ -1 +1 @@
-{"null": 1.0379271266124754}
\ No newline at end of file
+{"null": 1.3095685925398302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1354.json
index a02239b37fe..3538311983f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1354.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1354.json
@@ -1 +1 @@
-{"ATOSIBAN": 287.70864136046146, "METHOTREXATE": 11.590866869201236, "SYNAGIS": 165.70738011159432, "null": 1.644846136690553}
\ No newline at end of file
+{"COMIRNATY": 0.4516016830293282, "DEXAMETHASONE": 3.9249131775460726, "FORSTEO": 2.9879697977471733, "LANTUS": 1.1181681273118154, "NEXAVAR": 1.9278218135258407, "OMALIZUMAB": 4.819021389575098, "SAXENDA": 47.086584547086616, "SPIKEVAX": 0.4470633692782436, "TOZINAMERAN": 0.4476804889831312, "TRULICITY": 4.9969585461101165, "VAXZEVRIA": 0.5488299487516615, "XELJANZ": 1.2873560374572652, "null": 1.1475545258276103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1355.json
index fb60c87301d..1f8ec2c6826 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1355.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1355.json
@@ -1 +1 @@
-{"null": 1.120285772347113}
\ No newline at end of file
+{"null": 0.8441661466746129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1356.json
index db38cfce778..e3dc0d38b83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1356.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1356.json
@@ -1 +1 @@
-{"AMIKACIN": 1.5871199998976375, "ARIXTRA": 3.66512353857739, "BRIDION": 55.96646119030744, "BRIVIACT": 1.6080963460444382, "BUDESONIDE": 1.1615504413803206, "CAELYX": 6.762408595565901, "CANCIDAS": 3.6155505404586346, "CELECOXIB": 2.5304798082742943, "COAPROVEL": 1.0173833058053336, "DARZALEX": 9.632793347678753, "DEXAMETHASONE": 3.0233596803325407, "FASENRA": 2.579408739712399, "FASLODEX": 1.157035393099346, "FASTURTEC": 34.28335993372861, "FENTANYL": 9.853061391939509, "FLEBOGAMMA": 6.6132311800444725, "GAZYVARO": 4.758965037954392, "HYDROCORTISONE": 2.039325425910312, "INCRUSE": 1.576885842836377, "KIOVIG": 3.6483714107038696, "LEVOFLOXACIN": 1.0836423279624166, "MABTHERA": 1.8599868287085557, "MEPOLIZUMAB": 1.0337615108436464, "MIDAZOLAM": 10.829179709070996, "NAGLAZYME": 7.0777177538668345, "NUCALA": 3.5906078473650016, "OMALIZUMAB": 1.24178982678185, "ONCASPAR": 20.408095103681894, "ORKAMBI": 5.628203537675902, "PRIVIGEN": 4.148995036433701, "PROPRANOLOL": 2.311209061697214, "QARZIBA": 6.616126976354259, "RAPISCAN": 24.44311556697105, "RELVAR": 3.936047924660193, "RIXATHON": 7.977436285500203, "SUFENTANIL": 67.14935774584228, "SUGAMMADEX": 39.75421879118719, "SYNAGIS": 1.8547753926828248, "TOBI": 71.21449624211903, "TOBRAMYCIN": 9.03659129074215, "TOPOTECAN": 42.62914140024444, "XOLAIR": 6.079094022198634, "null": 4.0409257328201145}
\ No newline at end of file
+{"ADALIMUMAB": 1.0300088712541255, "BYETTA": 16.814749060546795, "JANUMET": 22.494885087138755, "JANUVIA": 28.948313782289134, "null": 0.9317006008869824}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1357.json
index 1c2ada60c8f..f85cba7032b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1357.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1357.json
@@ -1 +1 @@
-{"ANORO": 28.00963158520351, "SUFENTANIL": 74.50156901244907, "null": 7.23983070600359}
\ No newline at end of file
+{"BYETTA": 47.36012791478623, "null": 1.818698090507184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1358.json
index bdee06d8f32..eff99fd1294 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1358.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1358.json
@@ -1 +1 @@
-{"null": 3.3430720110221044}
\ No newline at end of file
+{"AFINITOR": 3.237410783435237, "BYETTA": 35.72931859108263, "CABOMETYX": 6.744196152642999, "JANUMET": 27.95187539466176, "JANUVIA": 18.785304554755182, "LONSURF": 31.98337498721818, "NEXAVAR": 5.109036920593755, "PEGASYS": 2.3751071361874816, "STIVARGA": 6.794278220510165, "SUTENT": 1.472182925571304, "VOTRIENT": 4.3957767488551465, "null": 0.8113549723123527}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1359.json
index 57c8d2a8387..31fea7d3741 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1359.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1359.json
@@ -1 +1 @@
-{"MIMPARA": 2998.3560143191157}
\ No newline at end of file
+{"null": 0.4729342430326713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/136.json
index 3e501fe4c25..1b8fa553ff2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/136.json
@@ -1 +1 @@
-{"MABTHERA": 79.25371624289451, "RITUXIMAB": 16.793412356686332}
\ No newline at end of file
+{"null": 0.6354253074591604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1360.json
index c57232a4ba2..d6d410b6e00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1360.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1360.json
@@ -1 +1 @@
-{"null": 1.0073536249268118}
\ No newline at end of file
+{"JANUVIA": 10.085625649255206, "null": 1.1942236712703}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1361.json
index c72f8ba6ee6..e8bc6309019 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1361.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1361.json
@@ -1 +1 @@
-{"null": 1.0732449582396213}
\ No newline at end of file
+{"null": 1.3300182315182705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1362.json
index c47a2e91fdd..27758240a93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1362.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1362.json
@@ -1 +1 @@
-{"null": 5.941825469695847}
\ No newline at end of file
+{"null": 0.7618228783228234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1363.json
index 32a969c0513..f0401afe8dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1363.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1363.json
@@ -1 +1 @@
-{"ABILIFY": 6.649561515372604, "ARIPIPRAZOLE": 10.68217845131717, "BRINTELLIX": 28.71575180135699, "CHAMPIX": 1.465442170881197, "CYMBALTA": 6.947162682775729, "GARDASIL": 2.714721268938394, "KEPPRA": 1.666292646979178, "LATUDA": 17.753558010888593, "OLANZAPINE": 1.5552329221273922, "XOLAIR": 1.4049383931255086, "ZYPREXA": 2.483291708957956, "null": 2.700617782461273}
\ No newline at end of file
+{"null": 0.5234282361212452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1364.json
index d75ad52cbf8..ce23a3ac208 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1364.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1364.json
@@ -1 +1 @@
-{"BUSULFAN": 44.935351663465546, "SOLIRIS": 72.96835794595576, "null": 1.0898033567586842}
\ No newline at end of file
+{"null": 0.6576612364450601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1365.json
index b97cd2eea5b..65248aa90e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1365.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1365.json
@@ -1 +1 @@
-{"SIFROL": 236.9393873635864, "null": 1.711436342441292}
\ No newline at end of file
+{"ARAVA": 0.6912452070997005, "ASPARAGINASE": 13.61118293712399, "BEDAQUILINE": 15.179544476593026, "CANCIDAS": 14.859991202012823, "CICLOSPORIN": 1.3795545395685416, "CLOPIDOGREL": 1.037363068303125, "COMIRNATY": 0.0296291565673015, "EXJADE": 8.415419366528496, "EXVIERA": 19.84365712763798, "KAFTRIO": 7.558200897996182, "KALETRA": 7.593801338333776, "LEVOFLOXACIN": 1.7572450286432115, "NOXAFIL": 20.31168938613883, "PEGASYS": 0.8521353593766691, "PEGINTERFERON": 4.750818852246233, "PEGINTRON": 1.4837169402329775, "SOLIRIS": 3.0858455178312214, "STIVARGA": 7.916564433898229, "TASIGNA": 3.171039464239067, "TRACLEER": 12.174626518170689, "VFEND": 7.218602277848142, "ZYPREXA": 1.2833119492748803, "null": 1.6897907733118818}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1366.json
index 4a3f859fba2..5e1dacbb753 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1366.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1366.json
@@ -1 +1 @@
-{"ENOXAPARIN": 162.27271490426335, "null": 1.6852987521715004}
\ No newline at end of file
+{"null": 1.574165341041632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1367.json
index 6e5032f6b64..b12c8e4be1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1367.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1367.json
@@ -1 +1 @@
-{"AVANDIA": 4.871043275993024, "null": 3.6321815932817008}
\ No newline at end of file
+{"null": 2.2290866834232426}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1368.json
index d0d305259dc..8bcc0247769 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1368.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1368.json
@@ -1 +1 @@
-{"null": 1.374603616955125}
\ No newline at end of file
+{"null": 0.7679106097749703}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1369.json
index 6d22bf7fb3f..854a231aaba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1369.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1369.json
@@ -1 +1 @@
-{"AFINITOR": 2.113348141775294, "APROVEL": 8.415815319945708, "AVANDIA": 5.154379714731715, "CLOPIDOGREL": 2.7020030384458047, "DELAMANID": 13.986871751063044, "EFAVIRENZ": 9.554385342338607, "ENTRESTO": 11.71035244551503, "FASLODEX": 2.129040578776831, "FENTANYL": 3.320140851574768, "IRBESARTAN": 13.32397131700644, "JANUMET": 1.8246680728784608, "JANUVIA": 1.6401199260849315, "LEVOFLOXACIN": 1.792848374781394, "NOT": 7.8619749980933635, "RASILEZ": 8.672868725766053, "SPIRONOLACTONE": 23.01533555110131, "ZOSTAVAX": 1.650175029918787, "ZYPREXA": 1.8364738686588045, "null": 1.9742424381914545}
\ No newline at end of file
+{"null": 0.855331966490197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/137.json
index dcb8fc8cbbb..a13636ed3df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/137.json
@@ -1 +1 @@
-{"SUBOXONE": 29.492054904234347, "TRUVADA": 27.41597793612541}
\ No newline at end of file
+{"null": 0.6347991971088278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1370.json
index 34399a705a8..f5ac175156c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1370.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1370.json
@@ -1 +1 @@
-{"ABILIFY": 2.438039539429133, "ARIPIPRAZOLE": 2.6765516551233097, "AVANDIA": 5.488581106330056, "BEDAQUILINE": 6.514673507977062, "FENTANYL": 2.224249063477062, "IRBESARTAN": 9.853010291316506, "JANUMET": 2.052687411509297, "OLANZAPINE": 2.7729175962758785, "ZYPREXA": 2.09361369094556, "null": 2.385101126991965}
\ No newline at end of file
+{"ABILIFY": 14.405047208956498, "BRINTELLIX": 20.21125608828801, "COMIRNATY": 0.1230008651763469, "ZYPREXA": 5.963426213338195, "null": 1.820387970837421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1371.json
index ba1bc9710dd..25208dc9f4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1371.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1371.json
@@ -1 +1 @@
-{"ABATACEPT": 16.794693512512385, "ARAVA": 55.15942871392636}
\ No newline at end of file
+{"AZILECT": 344.266326098229, "COMIRNATY": 0.2414869626502112, "null": 1.517050123507546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1372.json
index 4f3c29c690d..987e8754836 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1372.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1372.json
@@ -1 +1 @@
-{"CICLOSPORIN": 24.746196164018816, "null": 2.34264995267084}
\ No newline at end of file
+{"COMIRNATY": 0.4692411674087145, "null": 1.3939001458506155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1373.json
index 9cbad01d2ad..0a333d07d66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1373.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1373.json
@@ -1 +1 @@
-{"null": 1.0575416466027538}
\ No newline at end of file
+{"null": 0.8839493325626656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1374.json
index a6d723f42e2..2c94de490f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1374.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1374.json
@@ -1 +1 @@
-{"CELLCEPT": 38.92957899242535, "CICLOSPORIN": 17.537664755469716, "CYTARABINE": 30.92677999308082}
\ No newline at end of file
+{"null": 1.908214514588308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1375.json
index 40906845589..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1375.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1375.json
@@ -1 +1 @@
-{"null": 1.4579362932943845}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1376.json
index 23c476f9942..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1376.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1376.json
@@ -1 +1 @@
-{"SUTENT": 2.1678413293455363, "null": 4.645521309575196}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1377.json
index 7f706c4adba..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1377.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1377.json
@@ -1 +1 @@
-{"null": 1.2695044214265356}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1378.json
index 3b6a2519325..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1378.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1378.json
@@ -1 +1 @@
-{"SUTENT": 6.895541164197233, "null": 3.643316454604004}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1379.json
index 257db080298..9f2e2d46100 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1379.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1379.json
@@ -1 +1 @@
-{"COVID19": 2.9877618189352444}
\ No newline at end of file
+{"SOLIRIS": 46.72572520895088, "null": 0.6257391853105589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/138.json
index 9c7ccb97d49..9d2592bc8d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/138.json
@@ -1 +1 @@
-{"KEYTRUDA": 5.986093193155452, "NEXAVAR": 10.778957736920356}
\ No newline at end of file
+{"RINVOQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1380.json
index c566681620c..59a45a75b16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1380.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1380.json
@@ -1 +1 @@
-{"null": 1.1966161126495616}
\ No newline at end of file
+{"NPLATE": 626.922686658039, "null": 0.5385705375614624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1381.json
index a14d8abf3b7..0e347a796d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1381.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1381.json
@@ -1 +1 @@
-{"ABILIFY": 1.036542007118334, "ABRAXANE": 2.8588241058322024, "ALDARA": 2.162931599365788, "APIXABAN": 13.452815762813104, "AUBAGIO": 2.3988901542729595, "BENLYSTA": 1.2447821815701017, "BIKTARVY": 1.0605550104896928, "BONVIVA": 1.1214231757495587, "BRINTELLIX": 1.2214068419574695, "BUPIVACAINE": 2.494994152406536, "CELECOXIB": 1.2960389814014064, "COMIRNATY": 1.3283698348318689, "CONTRAST": 4.498329746871734, "COSENTYX": 1.5754684367852354, "EMEND": 1.501910855185215, "ENBREL": 1.0676041825454523, "ERENUMAB": 1.9615820535183528, "FAMPYRA": 1.3372290670956437, "FASLODEX": 1.2780986889691155, "FIASP": 1.2542010124204075, "FIRDAPSE": 1.253027945122042, "FORSTEO": 1.4783527056440913, "HIZENTRA": 1.123149021069176, "HYDROCORTISONE": 3.305793005749032, "IMIQUIMOD": 4.472287690951847, "KESIMPTA": 1.36426041850766, "LANTUS": 1.0464381024391658, "LYRICA": 2.315685954320647, "MEPOLIZUMAB": 1.832178249406062, "NEXAVAR": 1.0163434823788862, "OCRELIZUMAB": 2.048363051342529, "OLYSIO": 1.1647968651704157, "OMALIZUMAB": 2.659814329413694, "OPTIMARK": 22.480802468608324, "OXYBUTYNIN": 1.06705587305285, "PLEGRIDY": 1.0602028257770078, "QUTENZA": 29.231661017085308, "SHINGRIX": 3.4613820752133324, "SPIKEVAX": 1.0410554484568084, "SUTENT": 1.371682306271677, "TOZINAMERAN": 2.0819961153917643, "TWINRIX": 1.291331378239469, "VAXZEVRIA": 1.0156015751737382, "XOLAIR": 1.1989064474244129, "null": 1.0121796019625169}
\ No newline at end of file
+{"null": 9.217845328203992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1382.json
index 10f5a9136cb..c4dbe0d4ddc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1382.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1382.json
@@ -1 +1 @@
-{"null": 2.8583683741825903}
\ No newline at end of file
+{"null": 3.1314410271800046}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1383.json
index 13f6a4c94e7..904bb4d996a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1383.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1383.json
@@ -1 +1 @@
-{"CHAMPIX": 13.019035498520289, "COMIRNATY": 1.4595645439076332}
\ No newline at end of file
+{"null": 11.069814789533677}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1384.json
index e751aa145ca..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1384.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1384.json
@@ -1 +1 @@
-{"QUTENZA": 484.92340337903954, "null": 2.3454861914388463}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1385.json
index 80253d6b911..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1385.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1385.json
@@ -1 +1 @@
-{"ADALIMUMAB": 23.40455271813838, "QUTENZA": 607.7326657258338, "null": 1.2012531161747084}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1386.json
index 4f147c408e4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1386.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1386.json
@@ -1 +1 @@
-{"null": 1.9317832073178371}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1387.json
index 19c0b373347..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1387.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1387.json
@@ -1 +1 @@
-{"METHOTREXATE": 25.03159398630535}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1388.json
index 866cc9a777b..b8e4bee0087 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1388.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1388.json
@@ -1 +1 @@
-{"ABACAVIR": 47.20459823749535, "ABATACEPT": 30.32749427483968, "ABILIFY": 1.840740068182464, "ADALIMUMAB": 30.92854617951778, "AIMOVIG": 3.1401533866807663, "AMINOSALICYLIC": 6.197631907260624, "APREMILAST": 16.22235912199517, "APREPITANT": 6.845969820040452, "ARAVA": 4.767716444208414, "CELECOXIB": 2.539527983175564, "CERTOLIZUMAB": 15.908669035902443, "CIMZIA": 1.8055239504902496, "COSENTYX": 3.795303492856888, "CYMBALTA": 2.355285992924158, "DULOXETINE": 2.761668199212698, "ENBREL": 2.164206841024705, "FASENRA": 1.0367471933997898, "HUMIRA": 2.7826611785405087, "MYCOPHENOLATE": 1.8339118508976573, "ORENCIA": 12.21398946587801, "PANTOPRAZOLE": 1.0548184913122114, "RITUXIMAB": 2.1205709233207566, "ROACTEMRA": 1.774374935568482, "ZOSTAVAX": 1.3722297750979446}
\ No newline at end of file
+{"null": 7.98428116366803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1389.json
index 26c599beb78..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1389.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1389.json
@@ -1 +1 @@
-{"ARAVA": 6.5922797978762935, "ROACTEMRA": 45.55672976524258}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/139.json
index 0be28b327e7..5b529df5a71 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/139.json
@@ -1 +1 @@
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\ No newline at end of file
+{"AMIKACIN": 89.69608075187472, "ZOSTAVAX": 11.876445600458094, "null": 0.4951556158540893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1390.json
index d7411b6c3b2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1390.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1390.json
@@ -1 +1 @@
-{"BENLYSTA": 28.126996441217948, "BUDESONIDE": 17.71583457045738, "CIMZIA": 4.213728663047349, "ENBREL": 5.1917373130449205, "KAFTRIO": 25.45847591435244}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1391.json
index e65103a936e..28121f4aaa0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1391.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1391.json
@@ -1 +1 @@
-{"null": 1.1425222380734628}
\ No newline at end of file
+{"null": 4.139418728484751}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1392.json
index 41141fa462c..bb6b15e329b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1392.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1392.json
@@ -1 +1 @@
-{"ABATACEPT": 17.56995773061908, "ADALIMUMAB": 107.44238709473872, "APREMILAST": 58.05933439558506, "ARAVA": 11.950270559436058, "COSENTYX": 4.4201398535117855, "MYCOPHENOLATE": 7.7084372572895585}
\ No newline at end of file
+{"null": 2.730503190934328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1393.json
index 1c60dd3770c..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1393.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1393.json
@@ -1 +1 @@
-{"ABATACEPT": 29.590680782105757, "ADALIMUMAB": 48.15333941329076, "AIMOVIG": 3.5459097328053164, "AMINOSALICYLIC": 7.442237717755549, "ANAKINRA": 30.275370316116856, "APIXABAN": 1.0285883929505482, "APREMILAST": 21.789986044552595, "APREPITANT": 8.214585091180096, "ARAVA": 19.30095736263544, "AZATHIOPRINE": 6.863650239501189, "CELECOXIB": 3.04590867013248, "CERTOLIZUMAB": 28.349040487497543, "CICLOSPORIN": 1.6341785393641703, "CIMZIA": 4.372986392654715, "COSENTYX": 3.9448274322019774, "ENBREL": 21.535569730360656, "ENTYVIO": 1.0637241658473569, "ERELZI": 10.186203244282844, "HUMIRA": 2.036057716825601, "IRBESARTAN": 1.949336340402484, "MYCOPHENOLATE": 3.4257231173121463, "RITUXIMAB": 1.431458824236587}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1394.json
index 4af8f24e7bd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1394.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1394.json
@@ -1 +1 @@
-{"ARAVA": 2.989895740836226, "CIMZIA": 6.778591043839805, "DASATINIB": 134.67193232387604, "ENBREL": 33.268955885801326, "HUMIRA": 34.479027743948826, "KYMRIAH": 31.558231966858525, "ROACTEMRA": 20.935020794155918, "XELJANZ": 3.93774690829397}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1395.json
index 372c972e5cc..9c21761c4fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1395.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1395.json
@@ -1 +1 @@
-{"ABATACEPT": 10.926748426316138, "ACLASTA": 4.508806645776192, "ACTRAPID": 1.208380028173876, "ADALIMUMAB": 12.525830480978518, "ADENURIC": 1.716799011326683, "AFINITOR": 1.4628278381328677, "AIMOVIG": 1.4104779869899555, "ALIMTA": 2.333829419537141, "AMIKACIN": 1.6610265763229723, "ANAKINRA": 11.551156548490807, "APREMILAST": 13.370135687516507, "ARAVA": 3.0563512391167804, "ARIPIPRAZOLE": 2.3449755784753115, "ASPARAGINASE": 1.149017185432782, "AXITINIB": 1.29528871829755, "AZATHIOPRINE": 2.307522088256549, "BAVENCIO": 3.689249932575298, "BORTEZOMIB": 1.070989517893541, "BRAFTOVI": 1.400274001777547, "CANCIDAS": 4.135054817194091, "CELECOXIB": 8.540027514261237, "CELLCEPT": 1.7684772694515978, "CERTOLIZUMAB": 15.29486526640891, "CICLOSPORIN": 2.85805471323886, "CIMZIA": 1.1982222704743752, "COMTAN": 3.2063918358434558, "COSENTYX": 4.870262000043046, "COTELLIC": 1.4444845750734423, "CUBICIN": 2.999257276831506, "CYTARABINE": 1.5161680850544457, "DABRAFENIB": 2.9745741184208128, "DAPTOMYCIN": 2.576513694743252, "DEXAMETHASONE": 1.0819230255189678, "DOCETAXEL": 1.0519691213825006, "EBIXA": 2.0664902694829395, "EMEND": 1.5724148458181813, "EMPAGLIFLOZIN": 1.2891957402697738, "ENBREL": 5.6046289040971216, "ENTRESTO": 1.434706731134706, "ENTYVIO": 2.044240116602396, "EPCORITAMAB": 11.71254140234428, "ERELZI": 9.455318084578147, "GAZYVARO": 1.3443225518878985, "GLIVEC": 1.177139315266524, "HUMIRA": 2.807075524235502, "HYCAMTIN": 1.972557512664391, "HYDROCORTISONE": 1.6515044836245256, "ICLUSIG": 1.4426868344330874, "INFLIXIMAB": 2.863773975197051, "IRINOTECAN": 1.1587869326205422, "ISCOVER": 3.014901573046446, "JAKAVI": 1.552443957382178, "KESIMPTA": 1.099741331009096, "KEYTRUDA": 2.1702735520472367, "KYMRIAH": 6.127000129911542, "KYPROLIS": 1.6732114385615422, "LEFLUNOMIDE": 7.850170346210012, "LEMTRADA": 5.296766845676344, "LENVIMA": 4.443000622909988, "LONSURF": 1.3667649585910968, "MABTHERA": 1.3016819766000018, "MEKINIST": 3.3208199504652347, "MELPHALAN": 1.4193364971507347, "MERCAPTOPURINE": 1.521843773269272, "METHOTREXATE": 2.931282845900943, "MICAFUNGIN": 6.414061249752139, "MYCOPHENOLATE": 1.4297941966303265, "NEXAVAR": 2.336644432733549, "OLANZAPINE": 1.08968793893185, "OPDIVO": 2.6225406050329614, "PEGFILGRASTIM": 10.39945341041051, "PEMBROLIZUMAB": 1.4069165384679467, "PREVENAR": 1.4170711672041854, "PROTELOS": 6.220816402775791, "REMICADE": 1.2620510648825145, "RILUTEK": 5.569495621042735, "RINVOQ": 3.308175966140888, "RITUXIMAB": 2.206613969590191, "ROACTEMRA": 1.9670400952342395, "RUXOLITINIB": 1.7296025233907792, "SKYRIZI": 2.1839893856036063, "STELARA": 1.5587868622257777, "STIVARGA": 2.944054792195961, "TEMODAL": 1.6112780199017367, "TOCILIZUMAB": 2.4315030799917805, "TORISEL": 2.218480462493136, "TWINRIX": 1.018296643328713, "VENCLYXTO": 2.2423657369786785, "VENETOCLAX": 1.7750030699161543, "VORICONAZOLE": 1.9324346320367445, "XELJANZ": 3.05852073877237, "XOFIGO": 1.0268970803202953, "YESCARTA": 1.327576610475168, "ZELBORAF": 1.0132916912128531, "ZYPADHERA": 1.1871562827161817}
\ No newline at end of file
+{"null": 0.5610331033905649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1396.json
index 54ed73afa8c..4e5b8e60189 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1396.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1396.json
@@ -1 +1 @@
-{"FORSTEO": 194.19005441068973}
\ No newline at end of file
+{"null": 1.7585140313756815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1397.json
index 83ec483909a..74007b5ddc9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1397.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1397.json
@@ -1 +1 @@
-{"SOLIRIS": 223.8140278735098}
\ No newline at end of file
+{"JANUMET": 45.94382712475179, "JANUVIA": 38.42672633533208, "TRACLEER": 70.25801614930803, "null": 0.6311871061950409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1398.json
index 7cfd381e690..344035aca38 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1398.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1398.json
@@ -1 +1 @@
-{"NEVIRAPINE": 2550.2278007409845}
\ No newline at end of file
+{"KALETRA": 32.78001317811359, "null": 1.5980017694149689}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1399.json
index 260f575a176..314e55022cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1399.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1399.json
@@ -1 +1 @@
-{"ABACAVIR": 25.96849687412544, "ATRIPLA": 14.30317134192232}
\ No newline at end of file
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/14.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/14.json
index 4ba31bb752e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/14.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/14.json
@@ -1 +1 @@
-{"ABACAVIR": 13.045411982848195, "AFINITOR": 9.759370540798306, "CICLOSPORIN": 8.69519941681243, "JANUMET": 10.352645198801184, "NEXAVAR": 14.390225556137}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/140.json
index e80c79ab8f0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/140.json
@@ -1 +1 @@
-{"ONGLYZA": 891.8311966297554, "SPIKEVAX": 1.002817946020664, "ZOSTAVAX": 7.199599984938528}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1400.json
index c26e2feb4dc..fb02fe4d8a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1400.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1400.json
@@ -1 +1 @@
-{"ABACAVIR": 16.693340216124966, "ATAZANAVIR": 11.57418142665117, "ATRIPLA": 2.9978228154580413, "BIKTARVY": 124.22977397105107, "CICLOSPORIN": 3.140671820463055, "COMBIVIR": 40.86046940252768, "DARUNAVIR": 52.85833010000207, "EMTRICITABINE": 24.19391661546745, "GENVOYA": 119.993372288535, "ISENTRESS": 26.003501328086987, "KALETRA": 37.35254727877938, "LAMIVUDINE": 43.354955896552994, "LEMTRADA": 16.80288543521944, "NEVIRAPINE": 60.09547117088065, "PEGASYS": 1.3526088069972082, "PEGINTRON": 4.0338954823160815, "STRIBILD": 7.833713108836502, "TRUVADA": 2.5722120246246014, "VIREAD": 10.5701402684543}
\ No newline at end of file
+{"OPSUMIT": 27.35997909895862, "null": 1.0460471173104462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1401.json
index 944791fae61..8753f67a250 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1401.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1401.json
@@ -1 +1 @@
-{"LAMIVUDINE": 261.3801588479279}
\ No newline at end of file
+{"null": 0.7330776708644279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1402.json
index e4b2652f84c..09625d32d70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1402.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1402.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"null": 1.5345798162876387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1403.json
index 6d98283e28e..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1403.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1403.json
@@ -1 +1 @@
-{"MEPOLIZUMAB": 2174.127046778093}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1404.json
index f98ac174a92..c6c7b3c1a51 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1404.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1404.json
@@ -1 +1 @@
-{"COMIRNATY": 8.211410280255809, "EPCORITAMAB": 3.060116380183333, "EVUSHELD": 10.8807155937457, "FASENRA": 1.1231052671847617, "JCOVDEN": 3.054348564843507, "KESIMPTA": 1.420628178299671, "MAVENCLAD": 2.2894308681030706, "OBINUTUZUMAB": 3.1403432501461808, "OCRELIZUMAB": 1.677700749609515, "OCREVUS": 1.3916721268954657, "PAXLOVID": 2.9767309870690646, "REMDESIVIR": 2.779836896160895, "RINVOQ": 1.2261848198144585, "RUCONEST": 1.7164490494305271, "SKYRIZI": 1.836940351593551, "SPIKEVAX": 1.4651320014237863, "SYNAGIS": 1.0621293632348667, "TOZINAMERAN": 4.375221065870345, "TRELEGY": 1.0174574856221212, "TREMFYA": 1.3515500269081926, "VAXZEVRIA": 5.04901041303239, "VEKLURY": 4.331611958135347, "VENCLYXTO": 2.160652354270927, "VENETOCLAX": 2.110093507661982, "XELJANZ": 1.0482002831905923}
\ No newline at end of file
+{"null": 3.091661048238552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1405.json
index bfec1ed43f3..6221529bc1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1405.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1405.json
@@ -1 +1 @@
-{"CIMZIA": 1.1161551629627522, "COMIRNATY": 4.746335166090454, "JCOVDEN": 14.321378354340272, "SPIKEVAX": 16.547311100504448}
\ No newline at end of file
+{"null": 1.2741546040657432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1406.json
index cfa3595a80d..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1406.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1406.json
@@ -1 +1 @@
-{"ACTRAPID": 10.448021533724388, "ADVAGRAF": 17.890807725906352, "ANIDULAFUNGIN": 38.77825477129275, "AZACITIDINE": 5.022562084400602, "CARFILZOMIB": 6.442341148300263, "CELLCEPT": 5.825062368821206, "COMIRNATY": 2.057750211588409, "CYTARABINE": 1.6705370152765244, "DARZALEX": 2.265119647307373, "DEXAMETHASONE": 4.713779535524051, "DOXORUBICIN": 2.4565337170204247, "ELIQUIS": 2.326858853898657, "EPCORITAMAB": 49.54761825988718, "EVUSHELD": 37.67549896918361, "FASENRA": 2.7191144290205216, "FIRDAPSE": 2.835437323855892, "JAKAVI": 2.029987564586436, "JARDIANCE": 2.6289045331425007, "KALETRA": 1.884702453785628, "LEVEMIR": 1.2179887175381825, "LOPINAVIR": 7.491260487825665, "MEPOLIZUMAB": 1.5423739246211583, "METHOTREXATE": 1.146249838794581, "MYCOPHENOLATE": 4.37840932876692, "OBINUTUZUMAB": 35.547773488051604, "OFEV": 2.2884836677368563, "REMDESIVIR": 34.16984159973498, "RINVOQ": 1.3819046347302195, "RITUXIMAB": 8.646541050166391, "RIXATHON": 9.656751711134955, "ROACTEMRA": 1.016058108998019, "SIMPONI": 1.1211200448054337, "SOLIRIS": 1.64994196402304, "SPIKEVAX": 2.2642297340864506, "SPINRAZA": 3.458310336004075, "TOCILIZUMAB": 7.916775757877641, "TOZINAMERAN": 2.033815460884681, "TRELEGY": 3.840290288463296, "TREMFYA": 3.3009901560394868, "VAXZEVRIA": 1.3963599879516997, "VEKLURY": 79.37823305738294, "VENCLYXTO": 10.228899579625168, "XELJANZ": 1.8246793363470009}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1407.json
index 58926ba5b44..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1407.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1407.json
@@ -1 +1 @@
-{"KALETRA": 465.56232101939474, "VEKLURY": 1780.4834397195566}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1408.json
index e40506af554..12a94b8b227 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1408.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1408.json
@@ -1 +1 @@
-{"null": 1.3577017580601636}
\ No newline at end of file
+{"BENLYSTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1409.json
index 189f5dc2889..6dede4261ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1409.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1409.json
@@ -1 +1 @@
-{"ABACAVIR": 21.08616618887081, "ATAZANAVIR": 2394.0921920514274, "EMTRICITABINE": 299.2731372212314, "LAMIVUDINE": 130.4136955617939}
\ No newline at end of file
+{"DEXAMETHASONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/141.json
index d01dcca0483..76005f9c027 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/141.json
@@ -1 +1 @@
-{"CICLOSPORIN": 2.14318407398394, "CYTARABINE": 7.054406070085901, "DEXAMETHASONE": 3.621903728955592, "EXJADE": 49.21185453598088, "JAKAVI": 31.334361788677946, "LYNPARZA": 15.207844750106952, "NPLATE": 11.176246968425763, "SOLIRIS": 5.949533547804612, "VFEND": 6.87834777051642, "null": 1.0304799964074234}
\ No newline at end of file
+{"null": 1.0060728874517513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1410.json
index 28125104d29..65f3b5a0084 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1410.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1410.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4651576029144424}
\ No newline at end of file
+{"JANUVIA": 230.84991083060143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1411.json
index 88a1d2dbdf5..5c9df36d017 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1411.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1411.json
@@ -1 +1 @@
-{"null": 1.0966247451530042}
\ No newline at end of file
+{"AZATHIOPRINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1412.json
index 42bef39ee0d..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1412.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1412.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 62.248037504330085}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1413.json
index 0cc8f0cbe6d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1413.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1413.json
@@ -1 +1 @@
-{"CICLOSPORIN": 9.170624640108924, "SPINRAZA": 767.8668887336981}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1414.json
index 4350cd74eae..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1414.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1414.json
@@ -1 +1 @@
-{"CICLOSPORIN": 9.589208678323471, "SPINRAZA": 130.96199138448975}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1415.json
index 4733886975f..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1415.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1415.json
@@ -1 +1 @@
-{"CICLOSPORIN": 10.265377362486792, "SPINRAZA": 61.07861641853554, "null": 1.4552901976754522}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1416.json
index 7e7fcc7717f..3a9d0cf08cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1416.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1416.json
@@ -1 +1 @@
-{"CICLOSPORIN": 51.96128368763689}
\ No newline at end of file
+{"null": 2.118328606160788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1417.json
index 25f68494b01..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1417.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1417.json
@@ -1 +1 @@
-{"null": 4.1423793880704975}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1418.json
index 1ffebc51a08..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1418.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1418.json
@@ -1 +1 @@
-{"null": 1.359417735449565}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1419.json
index 9ac0a8f0799..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1419.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1419.json
@@ -1 +1 @@
-{"ABACAVIR": 5.432932494579837, "ADCIRCA": 14.178485024584898, "AFINITOR": 4.862888257165355, "AMIKACIN": 9.841647946733753, "AVASTIN": 2.748447505008456, "BUPRENORPHINE": 2.584821650709686, "CAPECITABINE": 3.5900340812922424, "CICLOSPORIN": 2.657427595565616, "CRIXIVAN": 9.831482652221489, "DACLATASVIR": 24.54439833452568, "DARUNAVIR": 12.888059821691806, "EFAVIRENZ": 8.084096005892905, "ELTROMBOPAG": 109.45748141842796, "FORSTEO": 1.5204203932793907, "JAKAVI": 4.0974163910647965, "JANUVIA": 3.513754608801292, "JARDIANCE": 1.8670071068034224, "KALETRA": 14.552465989513538, "KEYTRUDA": 1.5668435845676416, "LAMIVUDINE": 7.106099736861508, "LEVETIRACETAM": 4.305684461103573, "NEXAVAR": 4.799714315454355, "OLANZAPINE": 1.3100695320260094, "PEGASYS": 1.2282536615320652, "PEMBROLIZUMAB": 4.193654564646776, "STIVARGA": 3.156855688692747, "SUTENT": 2.438355218905389, "TRACLEER": 1.932800640216533, "XTANDI": 1.5609943275570912}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/142.json
index 3e3b8e8ff5c..58837d6ed0a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/142.json
@@ -1 +1 @@
-{"LEFLUNOMIDE": 121.48399723409564, "RITUXIMAB": 41.44434942048056, "null": 1.3753456829556248}
\ No newline at end of file
+{"HEPSERA": 2329.632271930392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1420.json
index 018a5411891..7e3fde0389b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1420.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1420.json
@@ -1 +1 @@
-{"ABILIFY": 9.982037308704705, "ATAZANAVIR": 16.085530684191454, "BRIVIACT": 6.80543562182607, "CICLOSPORIN": 1.7941601618675296, "CIMZIA": 9.275905535585336, "COMBIVIR": 27.38231212110665, "CYTARABINE": 2.094640100912001, "DARUNAVIR": 9.07706023739452, "EFAVIRENZ": 16.722194616648817, "EMTRIVA": 26.86289957186088, "ENOXAPARIN": 5.479261196367649, "EPIVIR": 15.167831135866484, "FAMPYRA": 3.2125760278947717, "FENTANYL": 6.348876033352314, "GARDASIL": 2.726917553068876, "HYDROCORTISONE": 6.668218368323991, "IBUPROFEN": 1.9094946668369703, "INSULIN": 3.208071507238475, "ISENTRESS": 36.925571071590014, "JANUMET": 1.3619131961888191, "JARDIANCE": 1.1593717724385508, "KALETRA": 8.449346454504589, "KEPPRA": 9.446071649026395, "LEVEMIR": 2.5725167096039185, "LEVETIRACETAM": 2.828039017847453, "MIDAZOLAM": 4.137747097828348, "MMRVAXPRO": 1.79771217498666, "NEVIRAPINE": 31.671640644760345, "NORVIR": 37.7469176081207, "OPSUMIT": 1.1428930479991684, "PLEGRIDY": 5.184458923944389, "REYATAZ": 59.272017959283446, "RUCONEST": 15.033093308490317, "SOLIRIS": 1.6423656793056445, "STELARA": 2.4616034414355474, "SUBOXONE": 1.4230846107139503, "TOUJEO": 6.202470264167431, "VIMPAT": 5.660992204909679, "null": 1.4734034270208871}
\ No newline at end of file
+{"null": 2.7775622578935453}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1421.json
index bf58846293a..57894737908 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1421.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1421.json
@@ -1 +1 @@
-{"ASPARAGINASE": 409.5982213616621, "null": 1.0154320630092648}
\ No newline at end of file
+{"null": 3.189583679150163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1422.json
index 52a671a8663..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1422.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1422.json
@@ -1 +1 @@
-{"OMALIZUMAB": 348.7282203355524}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1423.json
index 7957fdffe98..9cf2cbedaea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1423.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1423.json
@@ -1 +1 @@
-{"CICLOSPORIN": 92.2405300457676}
\ No newline at end of file
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1424.json
index b6f384c5acf..c5edef39ed7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1424.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1424.json
@@ -1 +1 @@
-{"BELIMUMAB": 251.7007607167891, "BENLYSTA": 7.49986041760068, "FORSTEO": 11.234325312645652, "HYDROCORTISONE": 34.185383932214165, "KEPPRA": 2.8777720916993137, "null": 1.4589974520297448}
\ No newline at end of file
+{"ARIPIPRAZOLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1425.json
index ad168f9aad3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1425.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1425.json
@@ -1 +1 @@
-{"ARANESP": 6.873223493485576, "CINACALCET": 300.190411977793, "FORSTEO": 3.964565335270956, "IRON": 100.04045850853596, "MIMPARA": 153.1362978240474, "TERIPARATIDE": 159.30080992833138, "null": 6.153934836026213}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1426.json
index 38f87a8c8bf..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1426.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1426.json
@@ -1 +1 @@
-{"ATRIPLA": 3.749160713369047, "AVAMYS": 21.539035728952957, "ENTYVIO": 20.190796838059963, "null": 1.901701236143969}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1427.json
index 0f3ee75da40..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1427.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1427.json
@@ -1 +1 @@
-{"ABILIFY": 83.35343939989477}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1428.json
index c1ddd26a022..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1428.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1428.json
@@ -1 +1 @@
-{"null": 1.4824843710479705}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1429.json
index b307c3db30d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1429.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1429.json
@@ -1 +1 @@
-{"null": 1.3737295251571595}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/143.json
index 360d03a8c8e..54d4b7a6c22 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/143.json
@@ -1 +1 @@
-{"ASPARAGINASE": 42.91349536039485, "BLINATUMOMAB": 114.48249294546738, "BLINCYTO": 93.27382365872154, "BORTEZOMIB": 28.993445463826863, "BUSILVEX": 57.448449464922845, "BUSULFAN": 10.02491392024542, "CICLOSPORIN": 2.974401495734704, "CLOFARABINE": 81.50811653228288, "CYTARABINE": 23.18504132189374, "DASATINIB": 49.39375675496954, "DEXAMETHASONE": 6.220345287342108, "DOXORUBICIN": 6.604668079091947, "ICLUSIG": 69.15736258283168, "JAKAVI": 4.3067977696433815, "KYMRIAH": 90.54376377264838, "METHOTREXATE": 4.344493844457715, "REVLIMID": 15.259900200008904, "STELARA": 1.527986457104293, "TASIGNA": 7.485428183983045, "THALIDOMIDE": 15.812596111587196, "THERAPEUTIC": 200.72756871358172, "VFEND": 6.079314770104907}
\ No newline at end of file
+{"NOXAFIL": 2864.886879155343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1430.json
index ef5a9828b4a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1430.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1430.json
@@ -1 +1 @@
-{"ELIQUIS": 5.909672674219296, "JANUMET": 11.370737071065593, "null": 1.1920731948093168}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1431.json
index 209b2a46304..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1431.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1431.json
@@ -1 +1 @@
-{"ATAZANAVIR": 12.828423912730242, "BEDAQUILINE": 15.420153145337034, "CRIXIVAN": 66.57269202135188, "FORSTEO": 4.602650583245115, "FORXIGA": 5.930497112910753, "JARDIANCE": 4.979755256006145, "NORVIR": 112.9198028176019, "OMALIZUMAB": 19.933529875740696, "REYATAZ": 184.74203164834915, "SIMPONI": 2.5672126505802253, "null": 1.19277101820394}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1432.json
index f0bce90ef42..e5840a629ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1432.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1432.json
@@ -1 +1 @@
-{"OLANZAPINE": 84.78663070257144}
\ No newline at end of file
+{"ABILIFY": 5.578219738762844, "BRINTELLIX": 7.102179139056311, "CHAMPIX": 6.982177102643804, "COMIRNATY": 0.0435816313134996, "CYMBALTA": 3.9152794611957136, "CYTARABINE": 9.40081124182709, "LATUDA": 32.33995462696452, "OLANZAPINE": 20.51694246961485, "PEGASYS": 4.610085778720421, "PEGINTRON": 4.966625361874993, "ZYPREXA": 8.433214361337289, "null": 1.5692985944355478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1433.json
index 8a6227504ee..2daa84f17ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1433.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1433.json
@@ -1 +1 @@
-{"null": 9.338023666888736}
\ No newline at end of file
+{"null": 2.976407788570324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1434.json
index 867a5be3c3b..d8581b5d1ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1434.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1434.json
@@ -1 +1 @@
-{"AFINITOR": 6.824567845854038, "BYETTA": 3.9114837722627223, "CABOMETYX": 27.41865617305037, "DOCETAXEL": 5.909131265198146, "FASLODEX": 14.88551221002136, "IBRANCE": 23.03056015614105, "INLYTA": 10.024317565636322, "KEYTRUDA": 12.034035360388511, "LONSURF": 22.77968776464956, "NEXAVAR": 10.26437768483618, "STIVARGA": 17.15482893216877, "SUTENT": 8.961721650194969, "VOTRIENT": 3.3998452964372072, "XOFIGO": 58.63330464800885, "XTANDI": 19.53471988627772}
\ No newline at end of file
+{"ABILIFY": 15.755162315642222, "AIMOVIG": 1.756291212359283, "ARIPIPRAZOLE": 1.299805808231096, "ATRIPLA": 0.6104202234199332, "BIKTARVY": 5.280026385650897, "CHAMPIX": 8.401940997089007, "CIMZIA": 0.3894897587721684, "COMIRNATY": 0.0202261913304449, "CYMBALTA": 4.07672783548286, "ENBREL": 5.952575556198846, "FASLODEX": 1.2893362461750384, "HUMALOG": 0.9720634133937368, "KEPPRA": 1.1347185949698628, "LANTUS": 1.156623035498103, "LATUDA": 57.76609162170238, "LYRICA": 2.118496781426703, "OLANZAPINE": 6.209605028534195, "PEGASYS": 2.7897418349701733, "PEGINTRON": 1.4672641660028682, "SIFROL": 14.717135730229309, "SPIKEVAX": 0.0390680818650216, "STELARA": 0.4651745407053932, "SUBOXONE": 2.6545360872009467, "TAMIFLU": 1.4401304283761929, "TOZINAMERAN": 0.1070741239035844, "TRUVADA": 0.4298855178741656, "VIAGRA": 2.4014734358127616, "VIMPAT": 3.416398787187151, "XYREM": 6.017577541938056, "ZONISAMIDE": 47.7760182561827, "ZOSTAVAX": 1.8914206268217493, "ZYPREXA": 7.550605157566669, "null": 2.093938087481789}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1435.json
index 07853577233..6bc964dcf03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1435.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1435.json
@@ -1 +1 @@
-{"CICLOSPORIN": 11.393975614171238, "ELIQUIS": 3.3417155198641377, "KEYTRUDA": 11.258138919158805, "null": 1.186590717920084}
\ No newline at end of file
+{"null": 0.4211122573965482}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1436.json
index eaeda08c69c..9b9f1afc8d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1436.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1436.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 2.1130527141253905, "AMIKACIN": 19.01015777720368, "ANIDULAFUNGIN": 44.95447980235934, "ANORO": 5.039620040699715, "ASPARAGINASE": 5.918117277077505, "ATAZANAVIR": 1.577568362463256, "ATEZOLIZUMAB": 10.800806483576087, "AZACITIDINE": 4.14091601393544, "AZATHIOPRINE": 2.8468750057959404, "BEDAQUILINE": 6.310084126652108, "BEVACIZUMAB": 4.321454184568975, "BORTEZOMIB": 10.194915393785427, "BUDESONIDE": 1.8461622365129384, "BUSULFAN": 6.315696963843496, "BYETTA": 1.1947927916261858, "CAELYX": 2.6094743054828635, "CANCIDAS": 9.611115186967746, "CARMUSTINE": 5.469791678663731, "CASPOFUNGIN": 41.04627990913524, "CELLCEPT": 1.9182514251148612, "CICLOSPORIN": 3.49997986428728, "CIMZIA": 1.0180598670836594, "COSENTYX": 6.045459919024995, "CRIXIVAN": 2.9999920749246627, "CUBICIN": 4.7311635423765965, "CYTARABINE": 6.608983697144195, "DAPTOMYCIN": 21.135313253024226, "DEXAMETHASONE": 4.102949968995659, "DOCETAXEL": 1.3761889409463588, "EMPAGLIFLOZIN": 25.41204143331916, "EPIVIR": 2.671800635708834, "FORXIGA": 13.982095517778374, "HIZENTRA": 1.4107338872500597, "HUMIRA": 2.8393002074381046, "IBRANCE": 1.077698876911165, "IBUPROFEN": 1.015001639830676, "INFLIXIMAB": 3.014747463427676, "INLYTA": 1.220775774087001, "JARDIANCE": 15.833458235358629, "KALETRA": 1.0796692449250789, "KYMRIAH": 1.2589610574068768, "LEVOFLOXACIN": 1.5560531289633464, "LOPINAVIR": 12.82948398275084, "MEPOLIZUMAB": 1.697762666759134, "METHOTREXATE": 1.4249966719237364, "MICAFUNGIN": 32.02128236375394, "MYCAMINE": 30.64944417198894, "MYCOPHENOLATE": 1.5776082196973222, "NEULASTA": 2.610466698312362, "NOT": 2.76320646320378, "OMALIZUMAB": 1.0762602486434305, "PANTOPRAZOLE": 1.2504387595944666, "PEGASYS": 1.6051102105941673, "PEGINTERFERON": 1.6954497839509264, "PEGINTRON": 1.391257695539971, "POSACONAZOLE": 13.488552157105609, "RELVAR": 5.334674592976599, "REMICADE": 2.821203497001449, "RITUXIMAB": 2.4289256053844577, "SIMPONI": 1.4815348169933709, "SOLIRIS": 1.881885961415308, "SUTENT": 1.4164872914210038, "TACROLIMUS": 13.267752348376414, "TRELEGY": 8.759061066066417, "VFEND": 2.6185534434078788, "VORICONAZOLE": 9.04924073335292, "VOTRIENT": 1.038505256783835, "null": 1.0863883218063142}
\ No newline at end of file
+{"null": 2.4797871277346024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1437.json
index 12af19319b7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1437.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1437.json
@@ -1 +1 @@
-{"CICLOSPORIN": 34.3699203936446}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1438.json
index ce5decad536..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1438.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1438.json
@@ -1 +1 @@
-{"BASILIXIMAB": 83.3389577531939, "CASPOFUNGIN": 51.16930604706874, "CYTARABINE": 27.2784983733701, "DOCETAXEL": 17.748759751848592, "JARDIANCE": 7.745567236286045}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1439.json
index dc4fe9331d2..a070bdc3a06 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1439.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1439.json
@@ -1 +1 @@
-{"null": 3.774620949352752}
\ No newline at end of file
+{"FENTANYL": 231.17632356547304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/144.json
index f51c4558ca9..4f7cb8d6fae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/144.json
@@ -1 +1 @@
-{"ASPARAGINASE": 75.60729679708479, "BLINATUMOMAB": 535.6643440204251, "BLINCYTO": 595.8548514827819, "BUSILVEX": 56.284012797622, "CICLOSPORIN": 12.238778024425748, "CYTARABINE": 54.58684806722853, "DASATINIB": 199.56251423669676, "DEXAMETHASONE": 8.821967635439831, "ICLUSIG": 126.7784429543712, "KYMRIAH": 584.0499794171417, "MERCAPTOPURINE": 18.277856129889, "NILOTINIB": 26.79481134470553, "SPRYCEL": 16.003557433818624, "TISAGENLECLEUCEL": 213.7602463923735}
\ No newline at end of file
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1440.json
index 4f3ac2ead17..018dc524351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1440.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1440.json
@@ -1 +1 @@
-{"ANORO": 340.98668249017163, "VAXZEVRIA": 1.6350211373001882}
\ No newline at end of file
+{"MICARDIS": 36.44493719004928, "null": 2.1001316103540124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1441.json
index 8d4c6db155e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1441.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1441.json
@@ -1 +1 @@
-{"CICLOSPORIN": 18.470432833946195, "VAXZEVRIA": 1.7876143675243297}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1442.json
index 80585375b9a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1442.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1442.json
@@ -1 +1 @@
-{"COMIRNATY": 2.7819568356795674, "VAXZEVRIA": 2.6565024752590003}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1443.json
index 98c38a6a197..6ec2646a8c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1443.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1443.json
@@ -1 +1 @@
-{"BUSULFAN": 6.670903162944272, "CICLOSPORIN": 3.719432260322348, "CLOFARABINE": 113.56356207144614, "DINUTUXIMAB": 325.70387410689574, "EVOLTRA": 391.6026821910266, "FILGRASTIM": 33.26666426524781, "IPILIMUMAB": 9.122397677917748, "KEYTRUDA": 2.565222654944036, "KYMRIAH": 25.71118295925762, "NEULASTA": 22.197032567138663, "QARZIBA": 746.5600635311396, "VAXZEVRIA": 1.093750539556107, "YONDELIS": 78.05570506736963}
\ No newline at end of file
+{"APTIVUS": 39404.1228813144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1444.json
index 303659e8a6f..28dcb35cedb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1444.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1444.json
@@ -1 +1 @@
-{"AVASTIN": 10.372302789020672, "KEYTRUDA": 2.618172139112985, "LYNPARZA": 312.667381915897, "OLAPARIB": 103.72063657122432, "RUBRACA": 822.8072402865545, "ZEJULA": 285.5785119182075}
\ No newline at end of file
+{"ACTOS": 23.634531436107697, "ANORO": 1.2717919683028172, "ARAVA": 0.0932757031688571, "BYETTA": 1.0403944233554645, "CELLCEPT": 0.8909022561853879, "CHAMPIX": 0.2311599872919059, "CICLOSPORIN": 0.4581867468739446, "CIMZIA": 0.2495205338539151, "COMIRNATY": 0.0174187580734087, "COSENTYX": 0.8093004238500355, "ELIQUIS": 1.7328262134292314, "ENTYVIO": 0.7115704631401398, "ESBRIET": 1.56298306792714, "EXFORGE": 2.209249633112308, "FASENRA": 0.8519555227340521, "FORSTEO": 0.4913866190506021, "FORXIGA": 2.559911394640309, "HUMALOG": 0.5367697897390761, "JAKAVI": 0.5958739618316571, "JANUMET": 0.7722438934848928, "JANUVIA": 1.486676116256599, "JARDIANCE": 3.224592298861908, "KEYTRUDA": 0.273719390514341, "LANTUS": 0.7523692429369246, "METHOTREXATE": 0.4070989242910938, "NUCALA": 0.9578470128492934, "PLAVIX": 0.2983802381812239, "RINVOQ": 1.281898216951628, "ROACTEMRA": 1.0835075580857618, "SIMPONI": 0.5405878254073696, "SPIKEVAX": 0.0148262438614069, "STELARA": 1.621040547498653, "SUTENT": 0.1259160183153095, "TOVIAZ": 1.0798752269231695, "TRELEGY": 2.640474618825832, "VIAGRA": 1.284604201263595, "XELJANZ": 0.6542240538442541, "XOLAIR": 0.7162027971411815, "XTANDI": 0.9800652956709048, "ZOSTAVAX": 0.6646250923530665, "null": 9.43775644721086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1445.json
index 22a48f06fb9..eb726c0b201 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1445.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1445.json
@@ -1 +1 @@
-{"AFINITOR": 33.69136190591275, "DENOSUMAB": 115.4651345882878, "DOCETAXEL": 13.523293254243129, "FASLODEX": 67.4891485083566, "FULVESTRANT": 167.92569400882076, "IBRANCE": 24.36812550013488, "KISQALI": 43.474940418134246, "RIBOCICLIB": 358.6665543722972}
\ No newline at end of file
+{"CICLOSPORIN": 13.646180743707331, "null": 0.6264936854158752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1446.json
index 217345d3ea7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1446.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1446.json
@@ -1 +1 @@
-{"LONSURF": 42.57335920705888, "PEGASYS": 4.272514641406242, "STIVARGA": 39.69305559320301}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1447.json
index 6685dd9dafa..f7be4ec590f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1447.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1447.json
@@ -1 +1 @@
-{"IBRANCE": 90.97860162525856}
\ No newline at end of file
+{"null": 2.7373792987157866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1448.json
index 36d359c3245..4c0646ef5c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1448.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1448.json
@@ -1 +1 @@
-{"null": 1.2750659248573155}
\ No newline at end of file
+{"null": 2.530447090273517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1449.json
index 96999af3444..c865484fa95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1449.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1449.json
@@ -1 +1 @@
-{"ARAVA": 15.242397456482294}
\ No newline at end of file
+{"null": 2.415539241758726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/145.json
index bbaca30ab26..1d2d368d556 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/145.json
@@ -1 +1 @@
-{"BLINATUMOMAB": 834.8174089825604, "CYTARABINE": 133.8200401887634, "KYMRIAH": 132.35339382448248}
\ No newline at end of file
+{"LYRICA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1450.json
index be8a16b7531..ee371be7d5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1450.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1450.json
@@ -1 +1 @@
-{"ARAVA": 4.879140844356236, "DOCETAXEL": 14.264037409162777, "EXJADE": 8.212779660713503, "FENTANYL": 5.262965340808649, "GARDASIL": 3.3159886533305967, "KYMRIAH": 21.223514497999616, "null": 1.0737219241966398}
\ No newline at end of file
+{"ELIQUIS": 3.2583631692410924, "SPIKEVAX": 0.6223673354011722, "null": 1.0875890376538315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1451.json
index 2577004f7a4..0a333d07d66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1451.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1451.json
@@ -1 +1 @@
-{"ESBRIET": 13.032532561579837, "FENTANYL": 5.111180079081104, "TRACLEER": 14.45324761587982, "null": 1.3262841906158265}
\ No newline at end of file
+{"null": 0.8839493325626656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1452.json
index b93163039fb..f9772c9b332 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1452.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1452.json
@@ -1 +1 @@
-{"SPIKEVAX": 24.373665170271423}
\ No newline at end of file
+{"KETOCONAZOLE": 199.8597747404807, "TOVIAZ": 41.391904487724005, "ZYPREXA": 4.166996749933885, "null": 2.4626624409567994}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1453.json
index 3f7afc46793..4dd6a6ded0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1453.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1453.json
@@ -1 +1 @@
-{"null": 2.412726658986069}
\ No newline at end of file
+{"COMIRNATY": 0.9085126282698116, "SPIKEVAX": 1.101612656655146, "VAXZEVRIA": 0.4257338536130263, "null": 1.2796873895382284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1454.json
index 5351d8e1eca..e3314106237 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1454.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1454.json
@@ -1 +1 @@
-{"null": 1.5257893909976403}
\ No newline at end of file
+{"APIDRA": 2.336219350721648, "AUBAGIO": 17.765895855909957, "BUDESONIDE": 0.9451751801898344, "CHAMPIX": 0.7534591403148562, "CLOPIDOGREL": 2.5340610656706213, "COMIRNATY": 0.1997607313670564, "CRIXIVAN": 8.516030846607116, "ELIQUIS": 1.5623711927769877, "EXFORGE": 2.28905656664189, "FAMPYRA": 23.535713947017545, "FENTANYL": 1.1384086484326152, "GARDASIL": 1.4274411806183398, "HUMALOG": 1.668348756143618, "IBRANCE": 1.4723799627538487, "INSULIN": 2.551869422486978, "JANUVIA": 6.997635377179516, "JARDIANCE": 1.6161078507201383, "KEPPRA": 1.0851500203411673, "LANTUS": 1.37527004565886, "LEMTRADA": 3.2872257989616585, "LYRICA": 2.590664810996554, "PEGASYS": 0.4215692641497263, "SIMPONI": 1.1361490192319326, "SPIKEVAX": 0.0964863697396428, "SUBOXONE": 1.333802933096868, "SUTENT": 0.4106490900890256, "TOVIAZ": 25.227542981438216, "TOZINAMERAN": 0.5707924895990607, "TRELEGY": 3.567330506231302, "VAXZEVRIA": 0.1439490196269061, "XELJANZ": 0.956463953176949, "XTANDI": 2.411278278563966, "ZOSTAVAX": 3.1585839038730263, "ZYPREXA": 1.287215997675444, "null": 1.618863889062219}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1455.json
index a4a2dc8621d..6cc0aea1106 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1455.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1455.json
@@ -1 +1 @@
-{"AFINITOR": 9.251810685309112, "AVASTIN": 18.898545224348137, "BEVACIZUMAB": 20.637707371921536, "BRAFTOVI": 13.05382402111739, "CAPECITABINE": 14.10424306208571, "CAPRELSA": 73.06501686625204, "FASLODEX": 6.597636099990874, "FULVESTRANT": 45.54556704109553, "IBRANCE": 7.34746573046643, "IRESSA": 27.00912365139867, "IRINOTECAN": 16.19176160584576, "KEYTRUDA": 3.885256603698326, "KISQALI": 16.59629328567184, "LONSURF": 42.55156315410201, "PANITUMUMAB": 71.55271718577454, "RIBOCICLIB": 39.950177391668255, "STIVARGA": 85.28076811996347, "TAGRISSO": 42.61673227311675}
\ No newline at end of file
+{"SIMPONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1456.json
index a92345f4186..aa2ccaace36 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1456.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1456.json
@@ -1 +1 @@
-{"null": 16.412066977322873}
\ No newline at end of file
+{"null": 0.6279266014165759}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1457.json
index f5994d516c9..095bffdd434 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1457.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1457.json
@@ -1 +1 @@
-{"FENTANYL": 30.788693596009043, "LUTATHERA": 729.9988052503513, "LUTETIUM": 1264.3536851062606}
\ No newline at end of file
+{"AUBAGIO": 10.468867883142206, "COMIRNATY": 0.2670560910346392, "SPIKEVAX": 0.3122511260870169, "VAXZEVRIA": 0.7835715986595476, "null": 1.0281823357518882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1458.json
index e21cb7522a7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1458.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1458.json
@@ -1 +1 @@
-{"null": 1.6524088228168026}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1459.json
index 63e0d15f640..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1459.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1459.json
@@ -1 +1 @@
-{"AFINITOR": 35.26338707495082, "LUTATHERA": 372.307967345474, "null": 1.7711445444799552}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/146.json
index b83a13be223..46042d0d8cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/146.json
@@ -1 +1 @@
-{"COMIRNATY": 1.153233564153947, "COVID19": 1.6537411472262955, "SPIKEVAX": 1.290647246269581, "TOZINAMERAN": 2.8015398764998665, "VAXZEVRIA": 3.355011501588046}
\ No newline at end of file
+{"BYETTA": 39.49797397591037, "SPIKEVAX": 1.517127636651023, "null": 0.656008667067914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1460.json
index 8d288d08bfe..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1460.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1460.json
@@ -1 +1 @@
-{"AFINITOR": 25.124995252613115, "FENTANYL": 9.24313640406652, "PANTOPRAZOLE": 111.28891444343508, "SUTENT": 3.384368532312146, "null": 1.9276501453665944}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1461.json
index f256739e9e3..ce26f0fed3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1461.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1461.json
@@ -1 +1 @@
-{"AFINITOR": 124.10684493735268}
\ No newline at end of file
+{"null": 0.598986643806918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1462.json
index 9cca594b151..0a5e7f1f7a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1462.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1462.json
@@ -1 +1 @@
-{"GARDASIL": 46.591445822586}
\ No newline at end of file
+{"null": 0.6969875988624081}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1463.json
index 2be0356c4e3..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1463.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1463.json
@@ -1 +1 @@
-{"ELIQUIS": 18.2849970108985, "MEPOLIZUMAB": 14.567507667419768, "OPSUMIT": 11.329016963963122, "TRACLEER": 14.403070509007652, "null": 1.0902964307712537}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1464.json
index d35c8dce42d..3520b274e75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1464.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1464.json
@@ -1 +1 @@
-{"APIXABAN": 14.046934404415005, "ELIQUIS": 5.498799956298751, "SPIRONOLACTONE": 112.6449002631122}
\ No newline at end of file
+{"CICLOSPORIN": 10.772783764508834, "COMIRNATY": 0.7627875652323952, "SPIKEVAX": 0.4236567595466309, "TOZINAMERAN": 1.0219418357030194, "null": 1.2558505084358529}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1465.json
index c0602977320..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1465.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1465.json
@@ -1 +1 @@
-{"ARAVA": 1.114699857744628, "CLOPIDOGREL": 15.28714788047587, "null": 1.3692287696777046}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1466.json
index cd7847dc4a7..3491cb4bf8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1466.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1466.json
@@ -1 +1 @@
-{"ABILIFY": 1.059469303435583, "ALL": 1.6033294457407297, "AMBRISENTAN": 2.0899313990081123, "AMIKACIN": 1.1544034037898736, "ANGIOX": 12.874130494253755, "ARIPIPRAZOLE": 1.103617603256416, "ARIXTRA": 2.228897879388682, "AVANDAMET": 5.140590329875609, "AVANDIA": 6.976068509320149, "AZACITIDINE": 1.2264443846149569, "BARICITINIB": 16.209540481332596, "BEDAQUILINE": 1.461553998051587, "BELIMUMAB": 1.4329396618455812, "BENZODIAZEPINE": 7.560098872954715, "BRIDION": 23.45584766933434, "BRILIQUE": 3.0070814782614907, "BUPIVACAINE": 4.18691754692918, "BUPRENORPHINE": 1.5445968514194832, "CARIPRAZINE": 5.445184486571681, "CASPOFUNGIN": 1.3404023646454442, "CLOPIDOGREL": 1.0461970800542124, "CUBICIN": 1.6248209388348642, "DAKLINZA": 1.0765523974604978, "DEXAMETHASONE": 1.6226199245551622, "DEXDOR": 29.16191884508936, "DEXMEDETOMIDINE": 14.205922206338156, "DOXORUBICIN": 1.0646877273455368, "DULOXETINE": 3.1270333865134563, "EMPAGLIFLOZIN": 1.7397445667396965, "ENOXAPARIN": 1.221579376428317, "ENTRESTO": 1.5541797279300815, "ERBITUX": 1.0540785201304852, "EXFORGE": 1.403997719474365, "EXVIERA": 1.188127578081282, "FEBUXOSTAT": 1.3298865206912365, "FENTANYL": 8.814090582817029, "FESOTERODINE": 14.19815081421435, "GANCICLOVIR": 1.7590121425982712, "GLIBENCLAMIDE": 2.453516639566473, "GLUCAGON": 22.185338824506704, "HYDROCORTISONE": 1.2323332555108502, "IBUPROFEN": 2.560417477220527, "INTEGRILIN": 3.996731613952982, "IRON": 2.310532817045637, "ISENTRESS": 1.313451354961496, "JANUMET": 1.366619270020303, "JANUVIA": 1.00319403353513, "JEVTANA": 1.17804357767616, "KYPROLIS": 1.31754212929432, "LACOSAMIDE": 2.941854227651338, "LEVETIRACETAM": 1.594090036451216, "LINACLOTIDE": 71.16291199317672, "MIDAZOLAM": 8.956067360263303, "MIRCERA": 4.069832332566697, "MULTAQ": 2.258779567346792, "NAGLAZYME": 3.0666939014187347, "NALOXONE": 8.769090004829028, "NOT": 4.020238732148068, "NOVOSEVEN": 4.81014164974593, "NOXAFIL": 2.0398123914579114, "NPLATE": 1.745270910114413, "OLANZAPINE": 2.605185644985282, "ONGLYZA": 1.086622450683545, "OPSUMIT": 1.8893285295959603, "OXYBUTYNIN": 1.4460484995833194, "PALIPERIDONE": 3.400350905701708, "PLAVIX": 1.0748858202706066, "POSACONAZOLE": 1.1361345614345797, "PRADAXA": 2.631377587274264, "PRAXBIND": 4.893297045316147, "PREGABALIN": 5.010893064646591, "PRIALT": 6.58525693726546, "PROCORALAN": 6.443030353386238, "PROPRANOLOL": 8.977884804593621, "RANEXA": 1.4397739535015692, "RANOLAZINE": 3.9003529525993774, "RAPILYSIN": 12.686668756011954, "RAPISCAN": 27.998892804404505, "RASILEZ": 1.3842156937712922, "REGADENOSON": 24.92043848809712, "REMDESIVIR": 9.544766330907946, "REVATIO": 2.9202887497744503, "RIVAROXABAN": 1.3561024631908092, "ROSIGLITAZONE": 4.991640345160891, "SILDENAFIL": 3.117569094702355, "SODIUM": 5.691845298571863, "SOLIRIS": 1.756006490231358, "SOVALDI": 1.0951323378525075, "SPINRAZA": 4.748934470221276, "SPIRONOLACTONE": 1.0301298699179429, "SUFENTANIL": 12.445443274570842, "SUGAMMADEX": 16.758361704744704, "SYNAGIS": 2.315989397374406, "TAMIFLU": 1.1109899250115232, "TELMISARTAN": 1.0921512753854032, "THALIDOMIDE": 1.1270094503863024, "TICAGRELOR": 1.9240145208419843, "TOBRAMYCIN": 1.4644454323033549, "TOCILIZUMAB": 1.032574458573602, "TRACLEER": 3.413382068506249, "TRAZODONE": 31.970430033842455, "UNSPECIFIED": 19.10424750165365, "VALSARTAN": 1.4161958156533614, "VELTASSA": 1.2701395663436976, "VFEND": 1.3332851481601788, "VIAGRA": 1.4359809181431735, "VIMPAT": 1.761976393164037, "XELODA": 1.0083040764976132, "ZYPREXA": 1.5670206666523518, "null": 2.655410469420524}
\ No newline at end of file
+{"VICTOZA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1467.json
index 88702ff5af0..8dfb7488c87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1467.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1467.json
@@ -1 +1 @@
-{"null": 4.153486078936919}
\ No newline at end of file
+{"null": 0.557465518305392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1468.json
index f3866ad60b6..bd00e3b521a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1468.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1468.json
@@ -1 +1 @@
-{"AVANDIA": 123.18733186227288}
\ No newline at end of file
+{"null": 1.5494092413988425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1469.json
index d616075c562..5a45fa881a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1469.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1469.json
@@ -1 +1 @@
-{"null": 1.1647388436024968}
\ No newline at end of file
+{"HIZENTRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/147.json
index d7abc12ff40..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/147.json
@@ -1 +1 @@
-{"ADCETRIS": 90.6629433602092, "ALEMTUZUMAB": 1.4066512723200306, "ARANESP": 1.0263433194569351, "ARSENIC": 83.77124325345295, "ASPARAGINASE": 6.873000715560991, "AVASTIN": 3.104121818912148, "AZACITIDINE": 74.73891875752705, "AZATHIOPRINE": 1.361206578343493, "BEVACIZUMAB": 3.299038200365937, "BORTEZOMIB": 5.891836545351418, "BUSILVEX": 19.24598785197774, "BUSULFAN": 10.57452617726285, "CAELYX": 16.416231902655245, "CANCIDAS": 10.760892781397724, "CAPECITABINE": 1.8107619745119112, "CARMUSTINE": 42.75859542468945, "CASPOFUNGIN": 3.762917777509261, "CELECOXIB": 3.89436213905457, "CELLCEPT": 1.681499793291752, "CHLORMETHINE": 276.43165638827986, "CICLOSPORIN": 4.451723580644136, "CLADRIBINE": 27.049446793580245, "CLOFARABINE": 31.76048968967356, "COMBIVIR": 1.2886155140277469, "CYTARABINE": 18.521110045737835, "DASATINIB": 4.706006480316533, "DECITABINE": 64.1466668154165, "DEFITELIO": 21.37375107424446, "DEXAMETHASONE": 3.976809374618505, "DOCETAXEL": 8.819056743230345, "DOXORUBICIN": 11.517938374911369, "EXJADE": 18.52721990152359, "FILGRASTIM": 14.557095345878752, "HERCEPTIN": 5.563235931985917, "HYDROXYCARBAMIDE": 30.41008111356076, "ICLUSIG": 2.062949410630812, "IMBRUVICA": 5.146235502511118, "IRINOTECAN": 7.02028029248467, "JAKAVI": 29.87365126298891, "KYMRIAH": 1.7098606233922111, "LYNPARZA": 25.191849407431505, "MABTHERA": 4.141104142459735, "MELPHALAN": 9.619746996967937, "MERCAPTOPURINE": 13.298400265273283, "METHOTREXATE": 4.306534482996878, "MIDOSTAURIN": 31.715570770834983, "NEULASTA": 2.970203081668104, "NEXAVAR": 1.9652806737040895, "NOXAFIL": 24.785084851839628, "NPLATE": 17.345181884714155, "OLAPARIB": 18.25791755637005, "PACLITAXEL": 4.770223754526268, "RADIOTHERAPY": 133.503888480076, "REMICADE": 2.7029026858615635, "REVLIMID": 10.042940838343702, "RITUXIMAB": 4.829202071174824, "RUBRACA": 2.0236207879988832, "RUXOLITINIB": 16.14233706205119, "RYDAPT": 21.11643262684059, "SOLIRIS": 2.276415224685003, "TASIGNA": 1.7133340130029155, "TAXOTERE": 24.392855630902638, "TEMODAL": 4.699236292442226, "TEMOZOLOMIDE": 16.04641485252656, "THALIDOMIDE": 5.498676222119293, "VENCLYXTO": 45.275267894327605, "VENETOCLAX": 88.63350198770678, "VFEND": 18.24100091948522, "VIDAZA": 84.36671642793335, "VYXEOS": 24.820892408198187, "YESCARTA": 3.5334053952819207}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1470.json
index 0a5ade348ee..cf2fa019f45 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1470.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1470.json
@@ -1 +1 @@
-{"ADCIRCA": 466.59213295219536}
\ No newline at end of file
+{"null": 9.144616743387267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1471.json
index b92a7e5e04f..71c63cdaf93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1471.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1471.json
@@ -1 +1 @@
-{"null": 1.446303883097232}
\ No newline at end of file
+{"ADCIRCA": 214.99198798090544, "ELIQUIS": 6.873409679359086, "JARDIANCE": 7.438105698422514, "PLAVIX": 5.680099449167661, "STELARA": 4.785806571797277, "null": 0.5663448030912838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1472.json
index 9951796ecd2..9e07cc5b042 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1472.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1472.json
@@ -1 +1 @@
-{"AVANDIA": 13.037123620844204, "CLOPIDOGREL": 6.36854906882229, "FENTANYL": 44.002471369857226, "TESTOSTERONE": 99.10206935253902}
\ No newline at end of file
+{"CICLOSPORIN": 39.99593610759551, "null": 0.6576612364450601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1473.json
index 82499017be1..6520e2a3005 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1473.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1473.json
@@ -1 +1 @@
-{"COMIRNATY": 4.978901487778691, "FORSTEO": 1.407173473022816, "SPIKEVAX": 3.5631494543020046, "VAXZEVRIA": 1.1759901470419425}
\ No newline at end of file
+{"TOVIAZ": 96.28437012166049, "null": 1.20737020626416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1474.json
index 6454ff62ddc..1a8b595a2e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1474.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1474.json
@@ -1 +1 @@
-{"ACTRAPID": 2.652406787140249, "AMBRISENTAN": 2.335791926300617, "ANORO": 1.4976401508373962, "APIDRA": 1.63169035524813, "APIXABAN": 11.77491962924847, "AVANDAMET": 28.943638573777896, "AVANDIA": 27.684924740229363, "AZACITIDINE": 1.7377584240066537, "BETMIGA": 1.3130037138913575, "BEXTRA": 4.409715635119716, "BOSULIF": 3.738463972650453, "BYDUREON": 1.719531321039018, "CHOLESTAGEL": 14.166109860590428, "CIALIS": 7.922941329325782, "CLOPIDOGREL": 1.07455651004431, "COTELLIC": 1.308871394333995, "DULAGLUTIDE": 2.429750586831433, "DULOXETINE": 1.0891297507385085, "ELIQUIS": 10.864253896064886, "ENTRESTO": 2.196983400708476, "ERENUMAB": 1.73408055209507, "ERLEADA": 1.1218479894714173, "ESBRIET": 2.516440021759985, "ESOMEPRAZOLE": 1.0082684896189358, "EXFORGE": 1.5760519433735978, "EXJADE": 1.204620557064195, "FEBUXOSTAT": 1.551764011333446, "FORSTEO": 1.852534436708444, "GALAFOLD": 4.501018091845299, "GALVUS": 1.5211509777031422, "GENVOYA": 1.1904659201596997, "HERCEPTIN": 2.871957835538458, "HIZENTRA": 1.4140915614332892, "HUMALOG": 4.054980977755793, "HYDROCORTISONE": 1.0906204890320934, "IBRANCE": 1.17170134766778, "ICLUSIG": 2.729452683090871, "INCRUSE": 2.263635782204124, "INLYTA": 1.6101013427521922, "INSULIN": 2.1995237919962856, "ISENTRESS": 1.3019634101830375, "JANUMET": 1.516640718857657, "JANUVIA": 1.4981000098577733, "JARDIANCE": 1.5097986015750262, "KYPROLIS": 4.42402150238164, "LANTUS": 4.062059302160344, "LEVEMIR": 1.3417284700883747, "LYRICA": 1.080671929965611, "MEKINIST": 1.0499172126804022, "MIMPARA": 1.393513899374033, "MIRCERA": 1.1887526366553738, "NAGLAZYME": 2.6926295172548267, "NINLARO": 2.1757967178613757, "NPLATE": 1.5271651202558478, "NUCALA": 1.1722654881211845, "OBINUTUZUMAB": 3.986779381085997, "ONGLYZA": 3.4550616560584406, "OPSUMIT": 1.9550267193963773, "PLAVIX": 1.6267681077057858, "RANOLAZINE": 3.482669517586212, "RAPAMUNE": 2.206845174363937, "REVATIO": 8.737901114492137, "REVLIMID": 2.783740523035974, "ROSIGLITAZONE": 13.679936150459982, "RUCONEST": 1.1643736834009977, "SILDENAFIL": 1.217557902786393, "SPRYCEL": 2.8237789212132216, "STALEVO": 1.1186059749636108, "SUBOXONE": 1.2437129480885276, "SUTENT": 1.230846691740466, "SYNAGIS": 4.724349441298711, "TAGRISSO": 1.1903141259093355, "TASIGNA": 1.6721900428314462, "TESTOSTERONE": 1.1103198106090346, "TOUJEO": 2.6994414625406207, "TOVIAZ": 1.6489667147161164, "TRACLEER": 1.9604989011078284, "TRELEGY": 3.343008967766028, "TRESIBA": 1.0070967938542323, "TRULICITY": 1.3393337754964718, "VELTASSA": 3.0578904527014226, "VIAGRA": 3.807353323229152, "XELJANZ": 2.105963671589354, "XOLAIR": 1.1917181682423277, "XTANDI": 1.729548566294439, "ZOSTAVAX": 2.4051129467115966, "null": 1.2778598453102432}
\ No newline at end of file
+{"ARAVA": 2.812448869023186, "ELIQUIS": 3.7236843740390784, "null": 1.3175622279198935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1475.json
index ab7e68393fc..e36ac4c095e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1475.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1475.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 14.912323591567514, "AXITINIB": 17.498413234950416, "BRAFTOVI": 10.987264599353784, "CLOPIDOGREL": 1.67451593129259, "CYTARABINE": 3.820968920288356, "DEXAMETHASONE": 3.48688488441041, "DOCETAXEL": 4.619821581877209, "ELIQUIS": 1.0045048620619117, "ENTRESTO": 23.83435988466822, "FENTANYL": 2.4032192247223905, "HERCEPTIN": 74.86613243387622, "INLYTA": 5.371599943587871, "KEYTRUDA": 4.289649672982359, "KYPROLIS": 17.464612573566626, "MEKINIST": 4.445948014653985, "OLANZAPINE": 1.5217667886925377, "PACLITAXEL": 42.873290971667046, "STIVARGA": 3.819022199562944, "TAGRISSO": 12.327542922884517, "TRASTUZUMAB": 388.6841683303037, "VOTRIENT": 3.0123516808971083}
\ No newline at end of file
+{"null": 0.9814585982551852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1476.json
index df215e3764e..458f7c7cb84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1476.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1476.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.0371040138619378, "ABRAXANE": 1.1083606257228136, "ACTOS": 3.260921608008581, "ADCIRCA": 5.704150332788748, "ADEMPAS": 2.221142067979164, "ADENURIC": 3.3822210632874974, "AFINITOR": 1.7627420632046988, "ALIMTA": 1.2345822990587223, "ALISKIREN": 3.0825206504263787, "AMBRISENTAN": 4.728276824691063, "ANGIOX": 2.4778144360344303, "APIXABAN": 1.0767313261644085, "AVANDAMET": 3.788807156553192, "AVANDIA": 7.0215774819115175, "AVASTIN": 2.738780887016666, "AZACITIDINE": 1.3657200719944589, "BARACLUDE": 1.0720003794198378, "BORTEZOMIB": 3.046543801631906, "BOSENTAN": 5.970280361334661, "BOSULIF": 2.5304443993133185, "BRILIQUE": 2.4516980759958487, "BUMETANIDE": 9.040607814696198, "BUSILVEX": 3.039116890426894, "BUSULFAN": 1.4117772734882108, "CABOMETYX": 1.4327567186920631, "CAELYX": 1.961461523554792, "CARFILZOMIB": 7.921397964258017, "CLOPIDOGREL": 1.81601623174055, "COTELLIC": 1.887988387787068, "CUBICIN": 1.6096883643900748, "DAKLINZA": 2.567011987479085, "DAPAGLIFLOZIN": 4.303129724326497, "DARATUMUMAB": 2.293701102514334, "DARZALEX": 1.912214486240767, "DASATINIB": 1.9242358065904863, "DEXAMETHASONE": 2.1338163557211223, "DOCETAXEL": 2.7446753355863094, "DOXORUBICIN": 2.4277300173373115, "EBIXA": 3.715836983408749, "EDOXABAN": 10.567627143896214, "EFIENT": 1.0906321246890254, "ELIQUIS": 3.131069201716865, "EMPAGLIFLOZIN": 1.4528115319260868, "ENALAPRIL": 6.397124660390862, "ENTRESTO": 19.2762280312126, "EPCLUSA": 1.080384454170097, "EPIVIR": 1.225014159415223, "ERLEADA": 4.307459486215716, "ESBRIET": 1.0723825109833565, "EUCREAS": 1.0292802404673138, "EVENITY": 8.142897428970938, "EXFORGE": 1.7385494123254177, "EXJADE": 1.3183207750656705, "EXVIERA": 2.2370518557048134, "FEBUXOSTAT": 4.268200564347088, "FORSTEO": 1.3420636468063785, "FORXIGA": 2.883318147945532, "GALVUS": 3.016822651236728, "GAZYVARO": 1.3702468113008597, "GLIVEC": 3.492946868742859, "HALAVEN": 3.862892276276353, "HARVONI": 1.0566551984154529, "HERCEPTIN": 14.30394070145912, "ICLUSIG": 5.098870178541138, "IMATINIB": 1.005079361285646, "IMNOVID": 4.583356843038923, "INCRUSE": 1.412240565719084, "INLYTA": 2.5832122959487305, "INTRONA": 1.808356015664212, "INVEGA": 1.993560560319041, "IRESSA": 1.7294182633973116, "IRON": 2.221151480048332, "ISENTRESS": 1.0900132233997748, "IVABRADINE": 17.531825338352988, "JAKAVI": 3.2418268280113054, "JANUVIA": 1.6052542551853977, "JARDIANCE": 3.3275043759935667, "KARVEA": 2.4031115456880623, "KEYTRUDA": 1.6354428088961894, "KYPROLIS": 28.885854139518468, "LANTUS": 1.073920229806944, "LENVIMA": 4.314171500666581, "LIXIANA": 1.8706912414226355, "LYRICA": 1.184877935936919, "MABTHERA": 2.4231624543484327, "MEKINIST": 1.4558995532599874, "MELPHALAN": 2.6894368319022948, "METFORMIN": 2.63676534816854, "MEXILETINE": 11.69400575669215, "MICARDIS": 1.3827205701931151, "MIMPARA": 4.138387041176018, "MIRCERA": 4.08373523027156, "MULTAQ": 10.699500476481788, "NAGLAZYME": 2.5466420777667587, "NEVIRAPINE": 4.424284030530442, "NEXAVAR": 1.5900603876274235, "NILOTINIB": 1.005573988898793, "NOT": 1.028334027018106, "NOVOSEVEN": 1.313737630280423, "NOXAFIL": 1.4091074218102015, "OFEV": 1.20152184666626, "OMALIZUMAB": 1.200949030963977, "ONGLYZA": 46.56060290582624, "OPDIVO": 1.0809229585822775, "OPSUMIT": 5.412022013307429, "OSIMERTINIB": 4.929872617388778, "PACLITAXEL": 1.1348943770109323, "PANTOPRAZOLE": 1.9475506880978908, "PAZOPANIB": 2.169485130122355, "PERJETA": 4.754201012928661, "PERTUZUMAB": 7.725287309307281, "PLAVIX": 1.0715967206241694, "POMALIDOMIDE": 2.39347336043614, "PRADAXA": 3.289042336680393, "PRAXBIND": 2.7971980420437683, "PROPRANOLOL": 1.7753743509411883, "PROTELOS": 1.4965473076247024, "RANEXA": 2.222919889838336, "RANOLAZINE": 1.2324363058576318, "RAPAMUNE": 1.9078101149239448, "RASILEZ": 1.7013839736144574, "REBETOL": 2.3480582260699627, "REVATIO": 8.277920213256014, "REVLIMID": 1.7830734143618436, "RITUXIMAB": 1.0581902581447382, "RIVAROXABAN": 3.618114900962575, "ROSIGLITAZONE": 7.93055405535386, "RUXOLITINIB": 1.0952935186869686, "RYDAPT": 4.074940484846491, "SAMSCA": 15.724027385228675, "SCEMBLIX": 4.535799713528884, "SIFROL": 1.959660307711078, "SILDENAFIL": 3.3668424705518327, "SIMPONI": 1.1391903708354427, "SKYRIZI": 1.1543550623544925, "SOLIRIS": 1.6716878801648227, "SOVALDI": 1.905576971486755, "SPIRONOLACTONE": 3.636681709964913, "SPRYCEL": 4.0948822638290805, "SUTENT": 2.4896471732445598, "SYNAGIS": 1.625624969087144, "TADALAFIL": 6.524093131772856, "TAFAMIDIS": 15.080049937098195, "TAFINLAR": 2.1328680971681124, "TAGRISSO": 8.521493177010159, "TASIGNA": 2.7953130264371016, "TAXOTERE": 3.704832408648704, "TESTOSTERONE": 1.0548868627193906, "THALIDOMIDE": 2.8866464699666, "TOLVAPTAN": 10.880075358295745, "TORISEL": 1.7516377784715536, "TRACLEER": 7.173187375515088, "TRACTOCILE": 4.61775533056901, "TRASTUZUMAB": 7.603893313608792, "TRELEGY": 1.882339061659856, "TRESIBA": 1.059866438728426, "VALSARTAN": 8.19735253272758, "VEKLURY": 1.257886641386288, "VELCADE": 2.960813416272861, "VELTASSA": 1.4676317816963187, "VENCLYXTO": 1.419985683614089, "VENETOCLAX": 1.2789469218011444, "VFEND": 2.39340949510036, "VIAGRA": 1.2498327714972597, "VOTRIENT": 2.5651345852774097, "VYXEOS": 3.779580657587427, "XALKORI": 2.795446350918977, "XARELTO": 1.4669377810941353, "XOFIGO": 1.1119386994625684, "XTANDI": 1.7320812898918565, "YONDELIS": 5.4906114744960695, "ZYPREXA": 1.0632467113855737, "ZYTIGA": 8.675111561641678, "null": 1.1207864774576988}
\ No newline at end of file
+{"BETMIGA": 40.77052339943651, "COMIRNATY": 0.6806272715814675, "FORSTEO": 2.032389211148656, "GARDASIL": 1.5362598636124056, "JARDIANCE": 6.404547069347236, "OMALIZUMAB": 18.33285830043456, "SPIKEVAX": 0.6228975291208761, "TOVIAZ": 39.66649432765731, "TOZINAMERAN": 1.1287264900637086, "VAXZEVRIA": 0.7437983166418956, "null": 1.0557194904494056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1477.json
index 3329b38f18f..22476989ef0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1477.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1477.json
@@ -1 +1 @@
-{"BARACLUDE": 13.218519776758953, "BEDAQUILINE": 4.330301833171965, "BORTEZOMIB": 4.202158128334568, "BUMETANIDE": 48.36291223594856, "BUSULFAN": 2.0816267485492226, "CARFILZOMIB": 7.421852936463756, "CLOPIDOGREL": 3.048286172336096, "DARZALEX": 2.804596034246313, "ELIQUIS": 2.725192913895552, "ENTRESTO": 13.252002112572542, "EVENITY": 3.824127992436815, "FENTANYL": 1.4379452072332883, "FORXIGA": 2.3230811399883606, "HERCEPTIN": 7.144756622736439, "ICLUSIG": 5.71769684477199, "INLYTA": 1.6329041423907409, "JARDIANCE": 1.0135324260095553, "KEYTRUDA": 2.6857047442167103, "KYPROLIS": 30.085286773686374, "NEXAVAR": 1.762241597648767, "OLANZAPINE": 1.2800682828760546, "ONGLYZA": 18.328812141772666, "OPSUMIT": 3.359262120792448, "PLAVIX": 1.5119726471806507, "SIMPONI": 1.4720810007182887, "SPIRONOLACTONE": 7.21211825262986, "SPRYCEL": 1.6502736967897194, "TAGRISSO": 5.251452961857661, "TAMIFLU": 7.800588409694852, "TRACLEER": 6.1118079827408085, "VOTRIENT": 2.144540732028472, "XTANDI": 1.1955778159475925, "null": 1.0465428014862903}
\ No newline at end of file
+{"null": 2.1207699682059635}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1478.json
index 58bd49d5bea..2029f9ca386 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1478.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1478.json
@@ -1 +1 @@
-{"ALISKIREN": 12.410163552259036, "APIXABAN": 3.5522191955200424, "AVANDIA": 3.4220726169463966, "BEDAQUILINE": 7.646568244383743, "BLINDED": 114.53269885402406, "BUMETANIDE": 73.11199206741138, "CICLOSPORIN": 1.102095558104875, "CLOPIDOGREL": 3.482872869720398, "DAPAGLIFLOZIN": 28.612698340317383, "ELIQUIS": 3.017735585212816, "EMPAGLIFLOZIN": 9.437037854556277, "ENTRESTO": 37.40315701387538, "FORXIGA": 8.036677488926395, "IRBESARTAN": 7.355031865143697, "JARDIANCE": 1.4852143263267077, "KYPROLIS": 8.164183437982837, "MULTAQ": 10.43157828006213, "OPSUMIT": 1.2667252935648934, "PANTOPRAZOLE": 8.36695659827363, "REVATIO": 7.801808409739831, "SAMSCA": 94.06503655237576, "SILDENAFIL": 6.243108876084706, "SPIRONOLACTONE": 15.220407114938345, "TAGRISSO": 3.822153430360925, "TRACLEER": 4.221873232979084, "VALSARTAN": 66.99707054268391, "null": 1.2476030758179515}
\ No newline at end of file
+{"OXYBUTYNIN": 102.10703220327738, "PEGINTRON": 5.88492601916547, "TOVIAZ": 46.27468605207611, "null": 1.5765207454910468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1479.json
index 8588ba69d4e..961e09dafd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1479.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1479.json
@@ -1 +1 @@
-{"ACTOS": 9.667450362437316, "ADCIRCA": 2.2875743704171136, "ADEMPAS": 1.6973611534325048, "ALENDRONATE": 18.638656694126272, "AMBRISENTAN": 3.3151349492650053, "ANORO": 1.0416585372908052, "APIXABAN": 2.685448509104165, "ARANESP": 1.0674473774920463, "AVANDAMET": 104.4619512017606, "AVANDIA": 144.4540653622416, "BLINDED": 18.923635172649664, "BOSENTAN": 2.5059774437944573, "BOSULIF": 3.9616968463428615, "BUMETANIDE": 6.70058733729879, "BYDUREON": 1.127150934068588, "BYETTA": 1.4962134209179194, "CARFILZOMIB": 1.4172724648642587, "CELECOXIB": 1.1297477237111666, "DASATINIB": 1.6755104342329588, "DEXAMETHASONE": 1.2835672526198036, "DOCETAXEL": 1.0713167223707136, "ELIQUIS": 3.188745472850586, "ENTRESTO": 3.197487178637858, "ENVARSUS": 11.048272480415577, "ENZALUTAMIDE": 3.216598003308982, "ESBRIET": 1.983891993090075, "EVENITY": 1.4495649949939855, "EVISTA": 1.0858116671895917, "EXJADE": 2.621776447393862, "FEBUXOSTAT": 5.467350971924363, "HERCEPTIN": 2.782964151357341, "HUMALOG": 3.449788401241661, "ICLUSIG": 1.7199385313182702, "INCRUSE": 1.5803770681260685, "INSULIN": 1.5175539714511914, "JANUMET": 1.0188310369955886, "JANUVIA": 1.9963519082778487, "JARDIANCE": 1.8313139931940536, "KYPROLIS": 6.127066970679661, "LANTUS": 2.4310257887861546, "LEVEMIR": 1.460111595577823, "MELPHALAN": 2.3555939028127857, "MEMANTINE": 4.316877947941692, "MICARDIS": 1.2353973763311454, "MULTAQ": 8.483531432182094, "NAGLAZYME": 1.5537750870327265, "NEVIRAPINE": 2.2601849228807915, "NINLARO": 1.62628791989508, "NOT": 1.1562379700172525, "NPLATE": 3.0831628535593083, "ONGLYZA": 65.80874903938171, "OPSUMIT": 4.206451872560103, "OPTIMARK": 1.0735530513949776, "PLAVIX": 1.573508597794265, "PRADAXA": 1.469556380530124, "RANOLAZINE": 3.6445841185602887, "RAPAMUNE": 1.9788140652875748, "REVATIO": 10.945661905532177, "REVLIMID": 1.6600344481730718, "RIVAROXABAN": 2.6077167924750766, "ROSIGLITAZONE": 79.51624517906069, "SAMSCA": 3.5559463588167457, "SEMAGLUTIDE": 3.321421416109072, "SILDENAFIL": 1.3749928721783116, "SPIRONOLACTONE": 1.3207120507771242, "SPRYCEL": 4.369320382554774, "SUTENT": 1.0957692930729472, "TAGRISSO": 2.5075023229947604, "TASIGNA": 1.909566921514522, "TESTOSTERONE": 2.182295636042926, "TORISEL": 1.1215245432208354, "TRACLEER": 4.858158043253091, "TRELEGY": 3.1150042677692182, "TRESIBA": 1.979375105741751, "VELCADE": 2.4778059197327957, "VELTASSA": 6.160484277416457, "VOTRIENT": 1.0788567173960113, "XARELTO": 2.1761115184572914, "XTANDI": 1.7283085449915587, "ZOMETA": 2.054579128034899, "ZOSTAVAX": 2.059926702823945, "ZYPREXA": 1.0403690713817042}
\ No newline at end of file
+{"null": 1.141705649344067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/148.json
index b6a8272d616..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/148.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 8.578952651329592, "AZACITIDINE": 311.6572599101515, "BUSULFAN": 55.16017813971893, "CICLOSPORIN": 21.38704136798354, "CLADRIBINE": 44.58264613234225, "CLOFARABINE": 66.45208138161259, "CYTARABINE": 154.0440395667228, "EXJADE": 3.18253852827501, "FILGRASTIM": 24.1706337116965, "JAKAVI": 5.066241965662304, "MIDOSTAURIN": 193.72812723359, "RYDAPT": 145.84955215907334, "VENCLYXTO": 31.57815753876872, "VENETOCLAX": 116.81213716430454, "VFEND": 5.551240884017208}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1480.json
index bf6eeb945fa..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1480.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1480.json
@@ -1 +1 @@
-{"OPSUMIT": 42.57542337612482, "null": 1.7328698577579935}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1481.json
index 61a09cc036a..772da1529aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1481.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1481.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 2.555329929368152, "COMIRNATY": 1.844177786462664, "ELIQUIS": 4.022691021758137, "PLAVIX": 4.203533454656158}
\ No newline at end of file
+{"ELIQUIS": 12.997882411108954, "KEYTRUDA": 9.257874352443771, "null": 0.4250694734353579}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1482.json
index 84721729398..c079965f928 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1482.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1482.json
@@ -1 +1 @@
-{"AVANDIA": 1.4758720492012651, "BUDESONIDE": 1.05220941725197, "BYDUREON": 1.7028099172421731, "COMIRNATY": 1.29617450050547, "COVID19": 1.41526518529411, "ELIQUIS": 2.191255687269185, "MICARDIS": 1.8663176546336229, "MULTAQ": 3.7966228865027967, "SPIKEVAX": 1.765058518777629, "SPRYCEL": 1.4548654810331092, "TOZINAMERAN": 11.27084955773214, "TRELEGY": 2.6704896872507438}
\ No newline at end of file
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1483.json
index 8be03632367..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1483.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1483.json
@@ -1 +1 @@
-{"ENTRESTO": 51.483650746269966}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1484.json
index 895572d642b..90336b9b32a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1484.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1484.json
@@ -1 +1 @@
-{"AVANDIA": 7.3568156913836145, "CELLCEPT": 6.840302302485608, "FENTANYL": 4.756330496655121, "SUBOXONE": 6.242580803751714, "ZYPREXA": 3.188004540090515, "null": 1.1508753949864574}
\ No newline at end of file
+{"CICLOSPORIN": 15.37475840100739, "HUMIRA": 16.852078608984623, "PANTOPRAZOLE": 44.16162652746288, "STELARA": 9.04259883912143, "null": 0.3863033018362424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1485.json
index 6ac5d3e5c05..425edd19760 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1485.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1485.json
@@ -1 +1 @@
-{"null": 1.000143026188907}
\ No newline at end of file
+{"null": 0.9518920967503458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1486.json
index e1ea551ee73..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1486.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1486.json
@@ -1 +1 @@
-{"TOZINAMERAN": 5.255332320011857}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1487.json
index b0537d2dbc0..98d57f4857b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1487.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1487.json
@@ -1 +1 @@
-{"null": 1.561918659840594}
\ No newline at end of file
+{"AZACITIDINE": 75.60746659487052, "CICLOSPORIN": 4.106138368329935, "EXJADE": 8.574264750041122, "JAKAVI": 170.55760727137766, "KYMRIAH": 86.52630852031776, "NPLATE": 18.90257243573125, "null": 0.4620710318586173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1488.json
index 89737158012..79e36a79703 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1488.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1488.json
@@ -1 +1 @@
-{"null": 5.6671013587265735}
\ No newline at end of file
+{"DASATINIB": 332.5361763327955, "ICLUSIG": 292.1844386071012, "JAKAVI": 59.59556402375964, "SPRYCEL": 109.189024914848, "TASIGNA": 65.77579057403236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1489.json
index eeb1e300073..55c8000e710 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1489.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1489.json
@@ -1 +1 @@
-{"SPIKEVAX": 3.4914295347383075, "null": 1.0042380306967094}
\ No newline at end of file
+{"SPRYCEL": 220.8747091943709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/149.json
index 39513ae45ac..9263fa5f5ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/149.json
@@ -1 +1 @@
-{"AZACITIDINE": 316.805896993179}
\ No newline at end of file
+{"SYNAGIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1490.json
index 396fdfc7e24..3b4ffbabec6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1490.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1490.json
@@ -1 +1 @@
-{"ACLIDINIUM": 60.81870293394235, "ADALIMUMAB": 2.931889310545699, "ANORO": 3.461336603362694, "AVAMYS": 7.893784281673978, "AVANDIA": 3.039899499693559, "BENRALIZUMAB": 13.85179348447347, "BUDESONIDE": 1.715495855804459, "BYETTA": 3.011778049493324, "COMBIVIR": 16.44928080986794, "ENTRESTO": 2.148472368833928, "EPIVIR": 3.982613329617241, "EXJADE": 3.606484747885607, "HUMALOG": 1.1473799712047896, "INSULIN": 3.398524815325715, "ISENTRESS": 8.520292731590207, "JANUMET": 3.349674733504921, "JANUVIA": 3.010871062150327, "KALETRA": 2.420492024510065, "KEPPRA": 1.0347005192227652, "LAMIVUDINE": 5.138688176925462, "MEPOLIZUMAB": 3.9450835934059305, "PANTOPRAZOLE": 2.361995770392136, "PEGINTERFERON": 1.718494587334065, "RIVAROXABAN": 12.048183436293035, "ROTATEQ": 1.931332507019483, "ZOSTAVAX": 3.321291667150521, "ZYPREXA": 1.501277636248486, "null": 2.594658844746046}
\ No newline at end of file
+{"ASPARAGINASE": 35.1839188335527, "CICLOSPORIN": 7.071656402904941, "CYTARABINE": 29.330349030159496, "JAKAVI": 77.26328339680032, "null": 0.5525809469955191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1491.json
index 5ed686d3417..e8ee3c652ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1491.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1491.json
@@ -1 +1 @@
-{"null": 1.0067924667284014}
\ No newline at end of file
+{"BOSUTINIB": 141.19117004321186, "BUSULFAN": 20.95717322556629, "CYTARABINE": 11.018826704935348, "DASATINIB": 289.2587294832939, "GLIVEC": 151.94204221717925, "ICLUSIG": 230.3105141951547, "IMATINIB": 141.07187486164864, "NILOTINIB": 286.3203678106457, "SPRYCEL": 48.85539172091863, "TASIGNA": 277.42484462397425, "null": 0.0595177060045889}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1492.json
index 3016eca30a8..dbb2f079020 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1492.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1492.json
@@ -1 +1 @@
-{"EVEROLIMUS": 1370.9472851697726}
\ No newline at end of file
+{"null": 0.4076611556508092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1493.json
index 413a6243062..e4079eb49c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1493.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1493.json
@@ -1 +1 @@
-{"null": 1.4481593619296391}
\ No newline at end of file
+{"null": 0.6328555915525093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1494.json
index abd4fce25ff..02229c79705 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1494.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1494.json
@@ -1 +1 @@
-{"APIDRA": 2.707884562497488, "AVANDAMET": 14.58077631782412, "AVANDIA": 16.313545370563542, "BENLYSTA": 2.7978749982041404, "ELIQUIS": 1.8332705226348267, "HIZENTRA": 4.95932656514605, "HUMALOG": 1.7561563778208673, "INCRUSE": 7.908916315228619, "INSULIN": 1.7828960478703428, "JANUMET": 6.27055568912444, "JANUVIA": 3.0833737713961327, "JARDIANCE": 20.500149801187423, "LANTUS": 13.57608205122151, "LEVEMIR": 8.343784117306644, "NOVORAPID": 2.428297073316964, "NPLATE": 3.292851521059287, "NUCALA": 1.3217214516359193, "OPSUMIT": 9.174033394060451, "PLAVIX": 2.083659650300775, "RANOLAZINE": 38.77372094667076, "ROSIGLITAZONE": 52.14395134093398, "SIMPONI": 2.567181683262328, "STELARA": 2.628154024560199, "SYNAGIS": 95.26774454518748, "TRACLEER": 7.013534234440036, "TRELEGY": 11.459746273228568, "TREMFYA": 4.7150718345661184, "VELTASSA": 23.730704008947303, "XELJANZ": 1.95665726327193, "XTANDI": 1.425894778189702, "ZOSTAVAX": 2.415432798526544, "null": 1.0331084461808646}
\ No newline at end of file
+{"CLOPIDOGREL": 12.384953654361922, "COMIRNATY": 0.2276757436549975, "ELIQUIS": 6.343728109912386, "ENTRESTO": 5.182148408632219, "LIXIANA": 25.243346701233516, "PLAVIX": 13.804042945464918, "SPIKEVAX": 0.1552629124802728, "SUTENT": 1.0396044339337345, "TOZINAMERAN": 0.528668203876654, "VAXZEVRIA": 0.3485693481107723, "null": 1.7334020796792473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1495.json
index 8a252675cf6..6a5075b8fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1495.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1495.json
@@ -1 +1 @@
-{"ARANESP": 13.14843724982483, "ENTRESTO": 9.904013835479198, "TRACLEER": 15.925781071101683, "null": 1.965347835381153}
\ No newline at end of file
+{"CLOPIDOGREL": 7.966306504428912, "ELIQUIS": 16.931329785059223, "null": 0.5928483921194987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1496.json
index f0c273ff184..3b0ed86c868 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1496.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1496.json
@@ -1 +1 @@
-{"OPSUMIT": 52.08328124333962, "null": 1.5870959564812956}
\ No newline at end of file
+{"null": 1.7801097803014172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1497.json
index e3c9925877a..507fff90da6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1497.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1497.json
@@ -1 +1 @@
-{"ANORO": 4.871709030402021, "AVANDAMET": 19.937834517446312, "AVANDIA": 25.08712462002974, "BYETTA": 2.6532263708259225, "ELIQUIS": 11.066822507884291, "FORSTEO": 2.582728309175193, "HUMALOG": 1.2540326071164236, "HUMIRA": 3.767177563296787, "JANUMET": 3.721502944049016, "JANUVIA": 6.972863985995172, "JARDIANCE": 3.2558753923421766, "LANTUS": 4.2814370869064735, "OPSUMIT": 7.80984836768759, "PLAVIX": 3.981885956921984, "RANOLAZINE": 30.689058500274395, "TRACLEER": 5.623846725932027, "TRELEGY": 8.639498293114581, "VELTASSA": 7.452652347562415, "VIMPAT": 6.16087547004473, "XTANDI": 1.253178363445103, "ZOSTAVAX": 2.698815180337641, "null": 1.4307470058872431}
\ No newline at end of file
+{"COMIRNATY": 0.8980537119583631, "COSENTYX": 2.2482182870361287, "EYLEA": 7.001891859039442, "HUMALOG": 1.641392497980139, "SPIKEVAX": 0.6103657304037352, "TOZINAMERAN": 0.9465220205673948, "VAXZEVRIA": 0.4896387904708355, "ZOSTAVAX": 9.390135306904057, "null": 1.0883044466925778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1498.json
index f40ca8a23b0..556b0c0ec3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1498.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1498.json
@@ -1 +1 @@
-{"null": 2.2796882444559303}
\ No newline at end of file
+{"null": 0.9062558297406124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1499.json
index 066d2a6e875..12a11151d98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1499.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1499.json
@@ -1 +1 @@
-{"null": 1.4624188927890116}
\ No newline at end of file
+{"ABATACEPT": 22.64347244750191, "ADALIMUMAB": 31.394954171514797, "AIMOVIG": 42.20613433301681, "APREMILAST": 59.4378117934347, "ARAVA": 0.0916184232576048, "AVAMYS": 10.556652197272408, "CHAMPIX": 0.3941629899488975, "COMIRNATY": 0.830717770530605, "GARDASIL": 0.8321308812831587, "KEPPRA": 0.9602411373270971, "LATUDA": 3.237365173149017, "OLANZAPINE": 1.6173518203678714, "RITUXIMAB": 1.1679442609034862, "SPIKEVAX": 0.7349333864902644, "TOZINAMERAN": 0.9331366574539742, "VAXZEVRIA": 0.3930213342549236, "ZOSTAVAX": 0.420289450462908, "ZYPREXA": 0.7865490795773697, "null": 0.3474935759465958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/15.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/15.json
index 410ca63256e..fab5ca81e48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/15.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/15.json
@@ -1 +1 @@
-{"ABACAVIR": 4.55206955826119, "AFINITOR": 6.468663761623113, "CICLOSPORIN": 5.354082685958196, "CYTARABINE": 6.648450219714082, "ENOXAPARIN": 37.57806414249502, "ROTATEQ": 39.91776686321335, "ZOSTAVAX": 4.012595331183077}
\ No newline at end of file
+{"null": 1.22211340837723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/150.json
index d9c46b67959..3a75469ab41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/150.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 19.9330575042766}
\ No newline at end of file
+{"null": 0.7809000972385235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1500.json
index a323f79a050..e0ab81b631d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1500.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1500.json
@@ -1 +1 @@
-{"ALISKIREN": 66.91960566720492, "METHOTREXATE": 78.07940163432635, "null": 1.9398949049279548}
\ No newline at end of file
+{"ABACAVIR": 0.4697263428297157, "ABILIFY": 0.2505884736411625, "ADALIMUMAB": 0.3610384619767854, "AIMOVIG": 0.476185481345696, "ALIMTA": 0.4418982269467043, "APIDRA": 2.9443070747320896, "APIXABAN": 10.354093139860606, "ARANESP": 0.3992931996537314, "ARAVA": 0.0665795562502112, "ASPARAGINASE": 0.5570889896013296, "ATRIPLA": 0.0543845512802594, "AUBAGIO": 1.0803212873067325, "AVANDAMET": 4.482629514624176, "AVANDIA": 3.3290183326233627, "AVASTIN": 2.159024193576497, "BEDAQUILINE": 0.8159630851758741, "BENLYSTA": 1.179832164247954, "BEOVU": 35.17948017097839, "BEVACIZUMAB": 2.895462535170649, "BOSULIF": 1.6109695791739076, "BRAFTOVI": 1.414475088766271, "BROLUCIZUMAB": 40.06329091219243, "BUDESONIDE": 0.224650248292818, "BUPRENORPHINE": 1.191637869560405, "BUSULFAN": 0.984552525844792, "BYDUREON": 1.3052865693334978, "BYETTA": 0.6259922590905284, "CELECOXIB": 0.8135501345408778, "CELLCEPT": 0.4753246101590033, "CHAMPIX": 0.5313654994287812, "CICLOSPORIN": 1.4554916936410558, "CIMZIA": 0.1214989373217684, "CLOPIDOGREL": 0.2583534411394246, "COMBIVIR": 0.5293582749544181, "COMIRNATY": 0.2366694310838228, "COSENTYX": 0.4956446607572408, "CRIXIVAN": 1.166740282181136, "CYMBALTA": 0.5311572766595022, "CYTARABINE": 0.3073328652049098, "DACLATASVIR": 2.910394317097917, "DESCOVY": 2.442932414071355, "DEXAMETHASONE": 0.1736568052760015, "DOCETAXEL": 0.2934410768195459, "EFAVIRENZ": 1.3055358361188758, "ELIQUIS": 0.8934275866862977, "ENBREL": 0.4135281395207654, "ENTRESTO": 0.858140865656065, "ENTYVIO": 0.2839888899449649, "EVISTA": 1.400243013635092, "EXFORGE": 1.3207925809427856, "EXJADE": 0.7104673239445458, "EYLEA": 43.813450473926906, "FASENRA": 0.9688221837697596, "FASLODEX": 0.2708797994854737, "FENTANYL": 0.2509489513422908, "FORSTEO": 0.2593720879104857, "FORXIGA": 0.2613785363330202, "GANCICLOVIR": 1.422340592981146, "GARDASIL": 1.4756946116141605, "HUMALOG": 12.932130858783392, "HUMAN": 0.8073876165626586, "HUMIRA": 0.2046223504087888, "IBRANCE": 1.7747572442464674, "INCIVO": 0.5566374579844219, "INCRUSE": 1.8317836363922315, "INLYTA": 0.7388547745732901, "INSULIN": 3.0205837069450068, "INTELENCE": 3.709520722607151, "IRESSA": 0.4783073894297163, "JAKAVI": 0.5611313143330091, "JANUMET": 0.8953438941037608, "JANUVIA": 0.5240302609972093, "JARDIANCE": 2.2001924088610147, "KEPPRA": 0.5806595288768905, "KEYTRUDA": 0.3513211624697382, "LAMIVUDINE": 0.9548520134926174, "LANTUS": 9.948749887007818, "LATUDA": 0.846761687790442, "LEMTRADA": 0.4503667095814868, "LEVEMIR": 4.996269848860576, "LEVOFLOXACIN": 0.1816341428379413, "LUXTURNA": 29.528157804574704, "LYRICA": 1.2516331795345894, "MEKINIST": 2.314009516060558, "METHOTREXATE": 1.0560677879997604, "MICARDIS": 1.0754457823046233, "NAGLAZYME": 2.930696847597626, "NEVANAC": 5.224102944279429, "NEXAVAR": 0.2795906711363036, "NOT": 0.9779444040984402, "NOVORAPID": 0.4634549829703157, "OPDIVO": 0.2794101187489299, "OPSUMIT": 0.3274912744041059, "OXYBUTYNIN": 1.7054815729153343, "PANTOPRAZOLE": 0.6022771845286308, "PEGASYS": 1.2573428912286189, "PEGINTERFERON": 0.6589187263892552, "PEGINTRON": 0.956994857858892, "PEMBROLIZUMAB": 0.6050357271405128, "PLAVIX": 0.8400488568145162, "PLEGRIDY": 1.1536367143516968, "RAPAMUNE": 2.990426319810477, "REVATIO": 1.150075225194309, "RIBAVIRIN": 0.5000540472072071, "RINVOQ": 0.3977324095336317, "RITUXIMAB": 1.1668626852348285, "ROACTEMRA": 0.7150238456191444, "RYBELSUS": 1.2891806479021664, "SHINGRIX": 0.9645506984794016, "SILDENAFIL": 2.7743084691538504, "SIMPONI": 0.5171349562537383, "SOLIRIS": 0.6991635760286891, "SPIKEVAX": 0.2890073821624264, "SPRYCEL": 0.5669352415565585, "STELARA": 0.441983137547889, "SUBOXONE": 0.6545364618797064, "SUTENT": 0.5322895808309634, "TAGRISSO": 0.6576318901870867, "TAMIFLU": 1.2083095021811616, "TASIGNA": 1.0497681545961228, "TOBRAMYCIN": 3.5442191013587165, "TOUJEO": 5.665544494556956, "TOVIAZ": 2.255868560268788, "TOZINAMERAN": 1.1099417111906258, "TRELEGY": 2.048993225143641, "TRULICITY": 2.665281332803318, "UMECLIDINIUM": 4.942673602406519, "VAXZEVRIA": 0.376331758995057, "VFEND": 2.007358988849574, "VIAGRA": 13.731050790795852, "VICTOZA": 1.4625206549231302, "VOTRIENT": 0.7176894965390018, "XALKORI": 1.9705946555242209, "XELJANZ": 2.2729967199252514, "XOLAIR": 0.4133152517402816, "XTANDI": 0.6153701155808006, "ZOSTAVAX": 8.260589427395859, "ZYPREXA": 0.6720114377032032, "null": 1.05119598024477}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1501.json
index 6093573c5bf..f3d9ac3b98a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1501.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1501.json
@@ -1 +1 @@
-{"null": 1.8541159603239652}
\ No newline at end of file
+{"null": 1.7303640841198316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1502.json
index 1eeb87d89a3..190c0b45eca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1502.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1502.json
@@ -1 +1 @@
-{"null": 2.0443614718434326}
\ No newline at end of file
+{"CICLOSPORIN": 13.553818104005853, "null": 1.508298889223416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1503.json
index 8185e6ed8cc..c12918faa66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1503.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1503.json
@@ -1 +1 @@
-{"SPIKEVAX": 6.002965258409991, "null": 1.6801798214955463}
\ No newline at end of file
+{"AERIUS": 5.940539891273659, "AFLIBERCEPT": 28.746271098669222, "AIMOVIG": 0.7333079552280299, "APIDRA": 1.6228504378415416, "AVASTIN": 2.856032098484932, "BEOVU": 44.23872226447951, "BROLUCIZUMAB": 30.42786773225056, "CHAMPIX": 2.712778228002888, "CICLOSPORIN": 1.2432041010370525, "COMIRNATY": 0.4111646890296423, "CYMBALTA": 0.4122035123827734, "EYLEA": 252.19620207983945, "FENTANYL": 0.885023545881254, "GARDASIL": 3.7372711912742287, "HUMALOG": 2.168023922964283, "JETREA": 63.62272212748079, "LANTUS": 0.9997619702337732, "PEGASYS": 1.1759556450154878, "PEGINTRON": 1.2386963471412618, "SPIKEVAX": 0.4605340486852369, "STELARA": 0.7648095214900679, "SUTENT": 0.2250905537293904, "TOZINAMERAN": 0.907526257536689, "TRELEGY": 3.1092662580705035, "TRULICITY": 1.3516257435309045, "VAXZEVRIA": 0.3769951905467694, "VFEND": 2.4104147160362044, "VIAGRA": 7.056607911421479, "ZOSTAVAX": 0.6321871416281354, "null": 0.973808971743114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1504.json
index c5f76e7e634..53440e9272c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1504.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1504.json
@@ -1 +1 @@
-{"null": 1.7213380385771686}
\ No newline at end of file
+{"APIDRA": 6.0071435062116, "ARAVA": 0.0710000594003582, "AUBAGIO": 1.9092598439359496, "AVANDIA": 1.789854954876147, "AVASTIN": 3.1645462352911022, "BEOVU": 24.55406213144068, "BYDUREON": 1.0922231421409792, "BYETTA": 0.9349324090352568, "COMIRNATY": 0.3676153258443027, "CYMBALTA": 0.3537722451241292, "CYTARABINE": 0.9299511972915524, "ELIQUIS": 1.1600024424900983, "ENBREL": 0.420773378163201, "EVISTA": 4.395097284598544, "EYLEA": 144.4170743073148, "FASLODEX": 0.9078185823808416, "GARDASIL": 0.6917492914655401, "HUMALOG": 11.9967899419334, "IBRANCE": 0.6744521794872125, "ICLUSIG": 5.637633234211379, "INSULIN": 2.5049992541720925, "JANUMET": 1.550385673207599, "JARDIANCE": 1.2650504376137992, "KEPPRA": 0.4152397153337949, "KEYTRUDA": 0.3085969937434491, "LANTUS": 9.289349879820826, "LEVEMIR": 5.340403860424591, "LYRICA": 0.8948164032884344, "MEKINIST": 2.2733837825056304, "NEVANAC": 10.516404783580237, "NUCALA": 0.6369167980896078, "PEGASYS": 1.1574213202269317, "PEGINTRON": 1.7010172017240754, "PLAVIX": 1.3437920864707298, "PLEGRIDY": 2.492668133578598, "REVATIO": 1.6060031373072634, "ROACTEMRA": 1.1268073817177189, "SHINGRIX": 0.921416023158096, "SILDENAFIL": 2.2911830730152403, "SPIKEVAX": 0.4684520756749971, "STELARA": 0.4150296231051164, "SUTENT": 0.2293625928277743, "TASIGNA": 0.8670572150904015, "TOZINAMERAN": 0.7147548959653273, "TRELEGY": 1.912612728158182, "TRULICITY": 1.885270432190976, "VAXZEVRIA": 0.2799766416080206, "VFEND": 1.1058024143470937, "VIAGRA": 14.988245792219963, "XELJANZ": 0.940113394942822, "XOLAIR": 0.7074916494526151, "ZOSTAVAX": 4.404750758477438, "null": 0.7868908088310719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1505.json
index 5082d7702db..49232e669fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1505.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1505.json
@@ -1 +1 @@
-{"ANGIOX": 99.2925357550834, "AVANDIA": 2.277359406197589, "AXICABTAGENE": 47.35308898612319, "BRILIQUE": 13.20432294678302, "BUSULFAN": 5.509416723798056, "CELLCEPT": 2.307137312288034, "CLOPIDOGREL": 9.51010582894025, "CYTARABINE": 3.167779705095913, "EFIENT": 35.57768761718435, "ELIQUIS": 6.629846756264094, "INTEGRILIN": 35.392869542997, "JAKAVI": 6.202155371558426, "KEYTRUDA": 7.992568934778222, "LEVOFLOXACIN": 3.3419244869663847, "PEMBROLIZUMAB": 4.039961880598208, "PLAVIX": 1.5094042941241197, "TAGRISSO": 5.463955370606241, "TAMIFLU": 2.7500536366681376, "TASIGNA": 4.113809368678278, "TRACLEER": 2.36056650742856}
\ No newline at end of file
+{"ABACAVIR": 0.3957082685236727, "ABATACEPT": 13.388410247714932, "ACETAMINOPHEN": 15.569127133051085, "ACTRAPID": 1.8889597828425475, "ADALIMUMAB": 10.413714540464053, "ADENURIC": 0.9647199622441056, "AFINITOR": 0.5488609995435175, "AIMOVIG": 1.106960482676104, "ALDARA": 1.5774866802258294, "ALEMTUZUMAB": 0.3219313923791237, "ALIMTA": 0.3903594616089393, "AMINOSALICYLIC": 2.0876604707061373, "ANAKINRA": 0.4145643967807093, "AP": 50.60769786611604, "APIDRA": 0.4690636186832456, "APREMILAST": 1.2016594056727152, "APREPITANT": 20.85342885254644, "ARANESP": 0.1644621140128742, "ARAVA": 5.228692936520289, "ARIPIPRAZOLE": 0.1410639560821588, "ASPARAGINASE": 0.2051389230144326, "ATRIPLA": 0.0350280221948639, "AUBAGIO": 0.6866397048153161, "AVANDIA": 0.1430156699366413, "AVASTIN": 0.2693979376247639, "BENLYSTA": 1.0160145588353082, "BETMIGA": 0.5137572152089365, "BOSULIF": 0.4678287451257977, "BRAFTOVI": 0.3071260337563913, "BRILIQUE": 0.2413831492729712, "BRINTELLIX": 0.2990792288728342, 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1.0817226141273906, "ROACTEMRA": 0.835449196333378, "RUBRACA": 0.4805288322470244, "SAXENDA": 0.3194789387694775, "SHINGRIX": 8.605461266346376, "SIFROL": 1.0522937601097866, "SIMPONI": 0.5192546895202609, "SORAFENIB": 3.4120996548188627, "SPIKEVAX": 0.3327521569504961, "SPRYCEL": 0.2928895573755388, "STELARA": 0.5208552785178089, "STIVARGA": 4.34699061045532, "SUBOXONE": 0.2122129176791903, "SUFENTANIL": 1.2925167547356289, "SUTENT": 3.321974955728798, "TAGRISSO": 0.3732304070973951, "TAMIFLU": 1.2877842685349177, "TASIGNA": 0.5627182366634986, "THALIDOMIDE": 0.5652471648591271, "TOUJEO": 0.3963895335046515, "TOZINAMERAN": 0.63897168229241, "TRACLEER": 0.2159541373638969, "TRELEGY": 0.2311036714999816, "TREMFYA": 0.8274271514447811, "TRULICITY": 0.2122407305837299, "VAXZEVRIA": 0.2510136104502768, "VFEND": 0.7133603287204922, "VILDAGLIPTIN": 8.470375359176595, "VORICONAZOLE": 0.9432812601167592, "VOTRIENT": 1.1016455789275283, "XARELTO": 0.5091697957369721, "XELJANZ": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1506.json
index 4f7407519c3..45e975944ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1506.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1506.json
@@ -1 +1 @@
-{"AVANDAMET": 11.853169181862691, "AVANDIA": 15.201628810813183, "BUDESONIDE": 2.58313229049446, "CLOPIDOGREL": 1.4274263099098612, "ELIQUIS": 13.090848354012389, "EVENITY": 6.364659014219273, "FORSTEO": 3.0276647605849765, "HUMALOG": 3.116608973153407, "LANTUS": 1.7460385808569978, "NAGLAZYME": 26.053764349524972, "OPSUMIT": 1.3709458003338464, "PLAVIX": 1.5314058889406317, "REVATIO": 7.127429426350858, "SIMPONI": 1.6749981489633554, "VIAGRA": 2.673370455057589, "XELJANZ": 1.3537844147411973, "XTANDI": 1.8120598132507628, "ZOSTAVAX": 1.5001556533586566, "null": 1.831764041070783}
\ No newline at end of file
+{"COMIRNATY": 0.2848178231584795, "SUTENT": 6.372662650728437, "null": 0.8688444000780573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1507.json
index 3a6a29015f0..edd267f3dea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1507.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1507.json
@@ -1 +1 @@
-{"CUBICIN": 458.9805810301239}
\ No newline at end of file
+{"ANAKINRA": 32.153824054436335, "METFORMIN": 449.7576783969333, "TAMIFLU": 10.521377997928758, "null": 2.0449479327268296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1508.json
index ee200c5e855..809c6a2c80b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1508.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1508.json
@@ -1 +1 @@
-{"null": 2.936222849208289}
\ No newline at end of file
+{"VANDETANIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1509.json
index d64a3c08b52..3567e569364 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1509.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1509.json
@@ -1 +1 @@
-{"CUBICIN": 323.29525612114486, "null": 1.0549324211197897}
\ No newline at end of file
+{"null": 1.1414720922686423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/151.json
index 4a8beb04f1c..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/151.json
@@ -1 +1 @@
-{"ACTOS": 3.4894149315316, "ADENURIC": 2.3601018908115656, "ANGIOX": 9.35550442101695, "ATAZANAVIR": 1.1510797908863586, "AVANDAMET": 23.618047233122965, "AVANDIA": 21.50512379412397, "AVASTIN": 1.7594890215185388, "BARACLUDE": 1.8709262706272625, "BLINDED": 27.47800415566948, "BORTEZOMIB": 1.00121130735562, "BRIDION": 1.29248945521256, "BRILIQUE": 9.094788349856982, "BYETTA": 1.0010735324803983, "CAPECITABINE": 1.2919660154477597, "CHAMPIX": 2.836886430456195, "CIALIS": 2.949585464929604, "CLOPIDOGREL": 7.865502278055255, "DAPAGLIFLOZIN": 8.230450875353094, "DASATINIB": 4.2402718731439375, "DOXORUBICIN": 1.9578716640861364, "EFIENT": 9.723389847598872, "ELIQUIS": 1.451051663506545, "EMPAGLIFLOZIN": 1.3064174934302732, "ENOXAPARIN": 1.2171473243639146, "ENTRESTO": 1.563030167607308, "ENZALUTAMIDE": 2.11438949342669, "EVENITY": 7.325563270362159, "EVISTA": 2.234215698031039, "EXVIERA": 1.8276693906964023, "EYLEA": 2.978288707545049, "FEBUXOSTAT": 21.613647337196824, "FORXIGA": 1.5113709451357114, "GLYCOPYRRONIUM": 4.219261580589798, "HARVONI": 1.5360139532089792, "HEMLIBRA": 3.300221122539162, "HUMAN": 1.5410087253930984, "HUMIRA": 2.1083863218627625, "ICLUSIG": 7.349228006838453, "INLYTA": 1.2816184495617535, "INTEGRILIN": 3.835703028270673, "JARDIANCE": 2.2614099076707594, "KYPROLIS": 3.221901239672089, "LENVIMA": 1.8275989815306384, "METFORMIN": 1.90772852411822, "MICARDIS": 1.2846593958325248, "NEXAVAR": 3.304658781788562, "NILOTINIB": 8.669747674408413, "NORVIR": 1.960364149307695, "NOT": 1.1155417090199211, "NOVOSEVEN": 9.381868743964557, "NPLATE": 3.7500235484250375, "OFEV": 2.8617991978765023, "ONGLYZA": 8.323788079628846, "PLAVIX": 5.3238830434327, "PRADAXA": 2.397096144436281, "RELVAR": 1.3027492679040125, "REMDESIVIR": 3.137319701777584, "RINVOQ": 1.5291706531051272, "ROACTEMRA": 1.6219111903405068, "ROSIGLITAZONE": 10.607729548212124, "SILDENAFIL": 5.27425411888543, "STELARA": 1.6150437416931385, "STIVARGA": 1.0099683777472122, "TASIGNA": 6.659416816532057, "TESTOSTERONE": 17.65475484534197, "THALIDOMIDE": 2.51947590093894, "TICAGRELOR": 8.448810431637515, "TRIUMEQ": 4.364114634545663, "VIAGRA": 3.071445946813132}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1510.json
index 29d9970689e..4aab17dd23b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1510.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1510.json
@@ -1 +1 @@
-{"ENTRESTO": 26.397360822912308, "FLUTICASONE": 208.5790853082887, "null": 1.4580272935030414}
\ No newline at end of file
+{"null": 2.1571591563082437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1511.json
index 2f97a1141aa..c11ba038ecf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1511.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1511.json
@@ -1 +1 @@
-{"ASPARAGINASE": 33.34410310302302, "AVANDAMET": 11.341652948128472, "AVANDIA": 11.47684906168181, "BRILIQUE": 4.67592896320986, "CLOPIDOGREL": 6.594604258241137, "ELIQUIS": 13.482786689681452, "ENTRESTO": 2.868965788929204, "JARDIANCE": 1.046325127147444, "NOVOSEVEN": 41.58012002717472, "PLAVIX": 2.288216277309869}
\ No newline at end of file
+{"null": 0.6442890977044572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1512.json
index 1c03b748104..bf67e53c9cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1512.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1512.json
@@ -1 +1 @@
-{"ACTOS": 1.9152755156138024, "ANGIOX": 9.684193719005332, "ANTIHISTAMINE": 28.557408124964653, "APROVEL": 3.511940130569955, "ARIPIPRAZOLE": 3.776769937929492, "AVANDAMET": 3.392282987161156, "AVANDIA": 6.213980049469706, "BARBITURATES": 26.3975180191986, "BENZODIAZEPINE": 72.47240226216957, "BENZODIAZEPINES": 19.565107598877976, "BRIDION": 6.101355923426213, "BRILIQUE": 1.6527939556431726, "BUPRENORPHINE": 3.434011060900461, "CANCIDAS": 1.067141766184603, "CELECOXIB": 1.3183310417369034, "COMTAN": 1.091266481322884, "DARZALEX": 1.1716995683425917, "DEXAMETHASONE": 2.2332003278149486, "DEXDOR": 12.93173515765512, "DRUG": 14.186664753926808, "DULOXETINE": 11.185779413143392, "EMEND": 1.6652974870016215, "ERBITUX": 1.3377411100940957, "ESOMEPRAZOLE": 1.5730558154515983, "EVENITY": 1.4139781503245694, "EXFORGE": 1.6636621417204325, "EXVIERA": 2.293777440128724, "FENTANYL": 6.978938647806461, "GALVUS": 1.164708735187607, "GLIBENCLAMIDE": 1.7615464407235597, "IBUPROFEN": 6.760083834301645, "ICLUSIG": 1.3847739089322564, "IRBESARTAN": 4.064952929141512, "JANUVIA": 1.287804590464197, "JEVTANA": 1.309351724111275, "LACOSAMIDE": 3.013959851288462, "LEVETIRACETAM": 1.226614526656293, "LINACLOTIDE": 35.994679443483, "MELATONIN": 1.519288884343735, "MIDAZOLAM": 5.166935993950047, "MIRCERA": 3.235657699172516, "MUSCLE": 155.41552010783303, "NAGLAZYME": 4.474758849921239, "NOT": 5.563850512307703, "NOVOSEVEN": 2.245226836950024, "OLANZAPINE": 5.881980776594869, "OPIOID": 150.16074822092176, "OPIOIDS": 12.917513539631653, "OXYBUTYNIN": 1.3105594825992115, "PANTOPRAZOLE": 1.5735495286256194, "PIOGLITAZONE": 6.227740874401152, "PRADAXA": 2.5605745715425776, "PRAXBIND": 5.181493971611359, "PREGABALIN": 4.437066995070747, "PREVENAR": 2.119375581134088, "RASBURICASE": 9.647796496922636, "REBETOL": 1.5361655286826563, "REMDESIVIR": 3.031695682983375, "REVATIO": 1.6275027343978823, "RISPERIDONE": 1.1412906865611838, "RIVAROXABAN": 2.7018355195017514, "ROSIGLITAZONE": 13.002599755829332, "SILDENAFIL": 2.598528224645253, "SOLIRIS": 1.4479809141743762, "SPINRAZA": 7.501035723460521, "SUFENTANIL": 11.00704668139615, "SYNAGIS": 2.4308459085667007, "TAMIFLU": 2.0566040796984324, "TELMISARTAN": 4.826456496855538, "TRACLEER": 2.4925442470817534, "UNKNOWN": 37.14500927552841, "UNSPECIFIED": 59.97668216800808, "VIMPAT": 1.3979303102368903, "XARELTO": 1.267689417947847, "ZYPREXA": 1.56900387040012, "null": 3.237164246953241}
\ No newline at end of file
+{"null": 3.7738708059543176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1513.json
index 793a447ab4d..21894391266 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1513.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1513.json
@@ -1 +1 @@
-{"null": 7.461888341814831}
\ No newline at end of file
+{"BIKTARVY": 128.9348046977465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1514.json
index 7789926438a..dc4beda7c41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1514.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1514.json
@@ -1 +1 @@
-{"null": 2.03937860268986}
\ No newline at end of file
+{"ENTECAVIR": 1119.2050576317483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1515.json
index e5d03603163..e24201d0304 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1515.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1515.json
@@ -1 +1 @@
-{"null": 5.896547399339858}
\ No newline at end of file
+{"ABACAVIR": 25.67870412641772, "ATAZANAVIR": 28.75277365359353, "ATRIPLA": 1.7816821620980827, "BIKTARVY": 172.74621696273675, "CABOTEGRAVIR": 190.6543567706349, "CELSENTRI": 84.61754071722183, "CYTARABINE": 17.218419021522823, "DARUNAVIR": 112.17517171113002, "DESCOVY": 152.8702349110133, "DOLUTEGRAVIR": 161.48362298599707, "EFAVIRENZ": 44.96172026973085, "EMTRICITABINE": 77.30947989876877, "EPIVIR": 28.836376872901727, "GENVOYA": 247.8087451022996, "ISENTRESS": 39.27736108716279, "KALETRA": 24.327525491333688, "LAMIVUDINE": 44.768193447434825, "REKAMBYS": 271.67295980081406, "STRIBILD": 8.017341240353831, "SYMTUZA": 181.838687104936, "TIVICAY": 113.2947565518387, "TRIUMEQ": 94.5397674005564, "TRUVADA": 5.4504545664058295, "null": 0.01771866453185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1516.json
index 836368064e6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1516.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1516.json
@@ -1 +1 @@
-{"null": 16.298584399143117}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1517.json
index e152b735651..4aab17dd23b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1517.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1517.json
@@ -1 +1 @@
-{"SPIRONOLACTONE": 11.764740399343404, "null": 16.37503001983234}
\ No newline at end of file
+{"null": 2.1571591563082437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1518.json
index 61f4ca0f7ac..bd76c2b8b24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1518.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1518.json
@@ -1 +1 @@
-{"ACLIDINIUM": 3.63159670714588, "ANGIOX": 21.47309423000936, "APIXABAN": 1.7363233156259623, "APROVEL": 2.287547268179808, "ARANESP": 90.56404506888036, "AVANDAMET": 5.5947484536308805, "AVANDIA": 7.421890013339674, "BEDAQUILINE": 2.565180070042742, "BORTEZOMIB": 8.686976265927408, "BRILIQUE": 4.325679497219267, "BUSILVEX": 15.663790544067131, "CAELYX": 2.455242648088, "CAPECITABINE": 2.4753862472502237, "CARFILZOMIB": 3.787799719375313, "CLOPIDOGREL": 2.3335780219453928, "DARBEPOETIN": 89.32334810185446, "ENTRESTO": 8.206561567190434, "ESOMEPRAZOLE": 2.0568882141465634, "FENTANYL": 2.469325583894748, "FLUTICASONE": 21.148008884305774, "GANCICLOVIR": 3.7547533692140367, "GLUCAGON": 33.14749217031573, "HUMAN": 2.352980698783336, "IBUPROFEN": 1.9670733849314872, "INTEGRILIN": 27.601603830101084, "IPILIMUMAB": 1.768056157500764, "IRBESARTAN": 5.037826818911573, "LOXAPINE": 25.85309436914321, "MELATONIN": 5.567231725404407, "MICARDIS": 3.3317117032888097, "MIDAZOLAM": 4.965314184854846, "OPSUMIT": 1.8795246178896632, "PEMBROLIZUMAB": 1.5973285190336175, "PLAVIX": 1.515762660373131, "PROPRANOLOL": 14.078627837631007, "REVATIO": 1.312983723945473, "ROACTEMRA": 1.1708973091960009, "SILDENAFIL": 5.457572158318087, "SUFENTANIL": 7.741719728053575, "TICAGRELOR": 3.040671287583894, "TRACLEER": 1.9143040743512565, "VALSARTAN": 4.632575611042719, "VIAGRA": 1.3035047666596773, "VOTRIENT": 1.112007744904621, "XARELTO": 1.3083644496482325, "null": 1.6873547102687247}
\ No newline at end of file
+{"null": 0.3370746845472986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1519.json
index 93027d2af30..b0e72972a8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1519.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1519.json
@@ -1 +1 @@
-{"ACTOS": 11.787601472968312, "ADCIRCA": 5.1029667003308985, "ARIPIPRAZOLE": 3.375218720684637, "AVANDAMET": 11.894069204386057, "AVANDIA": 13.114856039998877, "AVASTIN": 1.0877068084247492, "AZATHIOPRINE": 1.173684699944719, "BOSENTAN": 12.802095898522364, "BOSULIF": 2.384336105720248, "BUMETANIDE": 27.86399905350964, "BUPRENORPHINE": 1.857338572025315, "BUSULFAN": 1.464899647059145, "BYETTA": 1.982124154245464, "CICLOSPORIN": 2.350795836701095, "CYMBALTA": 1.0591841279412928, "DAPAGLIFLOZIN": 20.67409226058214, "DASATINIB": 8.784198340264332, "DEXAMETHASONE": 2.005164110781153, "DULOXETINE": 12.28176667648121, "ENTRESTO": 3.8053994364115713, "ENVARSUS": 63.15613650567877, "EVISTA": 2.9117040140855046, "EXFORGE": 2.3604090464674408, "EXJADE": 2.5713692830985493, "FENTANYL": 2.3016551892751624, "FESOTERODINE": 78.21093456841346, "FULVESTRANT": 2.881611804439055, "HYDROCORTISONE": 3.627989986137317, "IBUPROFEN": 2.164930251145773, "IRBESARTAN": 4.026338499462886, "JANUMET": 2.7831680377747445, "JANUVIA": 2.2170918546334955, "LEVETIRACETAM": 1.1208309688169862, "MELATONIN": 4.049634602542373, "MIDAZOLAM": 3.990734874356425, "NAGLAZYME": 2.968025056718841, "OPSUMIT": 1.4754704292229577, "OPTIMARK": 1.6008587340066545, "PEGASYS": 1.1521302688836277, "PEGINTRON": 1.3008452995580486, "SILDENAFIL": 3.838548750865446, "SPIRONOLACTONE": 4.053404230326045, "SPRYCEL": 2.342140589692949, "TASIGNA": 2.980649541307642, "TRACLEER": 1.7263589688261134, "VALSARTAN": 4.300357683712462, "XOLAIR": 1.192191372907967, "ZOMETA": 18.884744779447683, "ZOSTAVAX": 1.2118040892989113, "ZYPREXA": 1.5845452607862287, "null": 1.5612222299614869}
\ No newline at end of file
+{"ADALIMUMAB": 0.3186018253094375, "AFINITOR": 3.4621708253365675, "AMIKACIN": 6.092170882102, "AMINOSALICYLIC": 12.896221370899845, "ARAVA": 0.2336213881215403, "ARIPIPRAZOLE": 8.765449133550183, "ASPARAGINASE": 3.48755324015512, "BEDAQUILINE": 20.64720499396428, "BEVACIZUMAB": 4.083002261962488, "BYETTA": 1.3014951018803051, "CABOMETYX": 3.549654054084169, "CAPECITABINE": 3.4118776368735686, "CICLOSPORIN": 2.303600176394584, "CIMZIA": 0.37717569257396, "CLOPIDOGREL": 2.197430984077875, "COMIRNATY": 0.1298216147735015, "COSENTYX": 2.155060679856436, "DELAMANID": 23.40173086900297, "DEXAMETHASONE": 1.2349411488142046, "ELIQUIS": 0.6572757148187378, "EMEND": 11.072762026873674, "ENTYVIO": 1.3089927677075532, "EXFORGE": 2.9870501055939824, "EXJADE": 10.034358852646903, "FENTANYL": 2.2664768471674, "GARDASIL": 0.3992505343502514, "HUMIRA": 1.647606574854767, "IBRANCE": 1.3125637060708857, "INLYTA": 1.8199164910213417, "KEYTRUDA": 2.2711219128517586, "KYMRIAH": 7.287499776215023, "LENVIMA": 10.562859355633238, "LYRICA": 1.5444315925146062, "MEKINIST": 2.0691707348025967, "METHOTREXATE": 0.8378969869872516, "NALOXONE": 64.424764673388, "NEXAVAR": 6.378044209935301, "OCALIVA": 17.153475142848897, "OLANZAPINE": 1.3520648149162262, "OLYSIO": 9.268549993358006, "OMALIZUMAB": 1.8482475920307355, "OPSUMIT": 1.1380917288323045, "PEGASYS": 2.340341314977856, "PEGINTRON": 1.6096739600151655, "SOLIRIS": 3.501883505923867, "SPIKEVAX": 0.0689166181958137, "STIVARGA": 4.575094701203058, "SUTENT": 2.6279206576215093, "TOZINAMERAN": 0.1646090072727601, "TRACLEER": 1.5170898363714662, "VFEND": 4.080946502366965, "VOTRIENT": 2.402585991408558, "XALKORI": 6.441289094879018, "XELJANZ": 0.406080775446832, "ZYPREXA": 0.6925972059242816, "null": 0.9316479911685592}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/152.json
index cbc78c95605..9e8cf2477a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/152.json
@@ -1 +1 @@
-{"null": 7.560962273187651}
\ No newline at end of file
+{"APIXABAN": 307.166078937283, "BUDESONIDE": 117.82554711672606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1520.json
index 1e987f38e3f..16327a6e884 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1520.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1520.json
@@ -1 +1 @@
-{"ALIMTA": 1.423812560959525, "ARIPIPRAZOLE": 3.614045520542221, "ASENAPINE": 32.10236724451382, "ASPARAGINASE": 2.0773390698575485, "AVANDAMET": 33.29832491463044, "AVANDIA": 25.77657123942545, "AVASTIN": 2.681714525286883, "AZACITIDINE": 4.3059031483059576, "BEDAQUILINE": 3.888876601667241, "BETAFERON": 4.149613964252412, "BUPRENORPHINE": 1.064444261945216, "BUSULFAN": 1.4454184224113495, "BYETTA": 1.391637711498337, "CELLCEPT": 1.2475877041170855, "COTELLIC": 4.832497607997906, "CRIXIVAN": 6.105403076181301, "CYTARABINE": 4.113149728952029, "DAPAGLIFLOZIN": 5.394555322726371, "DOCETAXEL": 3.411860153821106, "DOXORUBICIN": 7.85212425884016, "ENTRESTO": 7.454447152644716, "EPIVIR": 4.148974458859302, "HERCEPTIN": 14.65855317058424, "ICLUSIG": 3.5179272264288315, "INLYTA": 1.0715781895523273, "IRESSA": 1.3429727775583966, "KALETRA": 1.85342461141393, "KEYTRUDA": 2.022878837981948, "KYPROLIS": 7.437395059637401, "LAMIVUDINE": 3.812885749307082, "LENVIMA": 2.9012502879927835, "MABTHERA": 4.673806257893796, "MANNITOL": 16.42023319680405, "MECASERMIN": 117.02464658818084, "MEKINIST": 3.503776402091129, "MELPHALAN": 4.745125392259742, "NPLATE": 1.9766164705184928, "OLANZAPINE": 4.186961524971776, "ONGLYZA": 16.35629485735435, "OPDIVO": 1.203056165982386, "OSIMERTINIB": 6.939818742311763, "PEGASYS": 1.186610208655684, "PEGINTRON": 2.1187359744430783, "PEMBROLIZUMAB": 1.102205267470734, "RITUXIMAB": 2.342071531028529, "ROSIGLITAZONE": 18.6057005735506, "ROTATEQ": 1.39796679126847, "SOLIRIS": 1.5848740458834674, "SPRYCEL": 1.082976973749025, "STELARA": 1.8640102077217335, "SUTENT": 1.6285163963468603, "TAGRISSO": 5.997049806132496, "TESTOSTERONE": 7.394616815611124, "TRASTUZUMAB": 49.084121584695424, "VFEND": 1.177487222024768, "VOTRIENT": 1.2799099212072862, "XOLAIR": 1.0262360677706754, "ZYPREXA": 1.797414073805505, "null": 1.252110695729869}
\ No newline at end of file
+{"COMIRNATY": 0.1244957012885319, "null": 1.1035402736344828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1521.json
index 2e4d86dd5ff..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1521.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1521.json
@@ -1 +1 @@
-{"null": 1.1232486692432602}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1522.json
index 03b778baaf1..ee192127fe6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1522.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1522.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"null": 1.2235218531283787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1523.json
index aae74a0243f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1523.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1523.json
@@ -1 +1 @@
-{"null": 1.1754565013842662}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1524.json
index 9be191649b8..41ac3090a34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1524.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1524.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 6.054997755175523, "AVANDIA": 5.294740101758958, "BEDAQUILINE": 41.90646033197992, "CELLCEPT": 2.2918419425225465, "CICLOSPORIN": 1.1782106598697908, "DELAMANID": 18.20601560147, "FORSTEO": 1.8449885919185816, "LEVETIRACETAM": 3.732807184881615, "MIDAZOLAM": 4.795883744671636, "NEXAVAR": 1.1912100042153615, "OPSUMIT": 2.2315585711772985, "SUTENT": 24.86169045308845, "TRACLEER": 11.494998527235657, "null": 1.133458806072282}
\ No newline at end of file
+{"CHAMPIX": 6.960079101487062, "null": 3.5120557602149383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1525.json
index a5565209c02..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1525.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1525.json
@@ -1 +1 @@
-{"ENTRESTO": 48.39212622070965}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1526.json
index 08092051460..e773eb8c2a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1526.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1526.json
@@ -1 +1 @@
-{"APIXABAN": 1755.0608311671162}
\ No newline at end of file
+{"DIET": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1527.json
index 0c51f62a87b..9a37545868a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1527.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1527.json
@@ -1 +1 @@
-{"ABACAVIR": 92.33324993520672, "ADEMPAS": 259.63979882364947, "null": 1.227006916875275}
\ No newline at end of file
+{"CLOPIDOGREL": 54.18376866362588, "null": 0.7267193828409113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1528.json
index 9cf67e4cef7..e393a18e1fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1528.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1528.json
@@ -1 +1 @@
-{"ASPARAGINASE": 9.010791390349253, "AVAPRITINIB": 288.3915723392538, "AVASTIN": 2.460869654027173, "BEVACIZUMAB": 4.407805301191615, "BORTEZOMIB": 6.771867693294144, "BUSULFAN": 5.151881238545597, "CAELYX": 20.606775732460548, "CAPECITABINE": 27.9252384050195, "CARFILZOMIB": 10.56078635281966, "CICLOSPORIN": 1.154992972452943, "CYTARABINE": 8.865183445218223, "DEXAMETHASONE": 4.376885719455959, "DOCETAXEL": 21.51273409866998, "DOXORUBICIN": 21.588565504985556, "HERCEPTIN": 33.84908456206, "ICLUSIG": 4.4571784064512965, "KEYTRUDA": 1.986017174840472, "KYPROLIS": 39.31032247622005, "LACOSAMIDE": 16.55230723782678, "MEKINIST": 4.198907467459966, "METHOTREXATE": 2.213649456317265, "OLANZAPINE": 1.428295135509733, "OSIMERTINIB": 26.771586678691445, "PACLITAXEL": 13.079300952149048, "PERTUZUMAB": 55.73073659640681, "RITUXIMAB": 2.8137131196543685, "SUTENT": 2.1792122194219776, "TAGRISSO": 4.967330641045299, "TRASTUZUMAB": 131.50693862250031, "VOTRIENT": 6.360747088098486, "XELODA": 8.364532985830472, "null": 1.895206373929924}
\ No newline at end of file
+{"null": 2.7691908625660115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1529.json
index 11a42dc4ba6..296007fc68c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1529.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1529.json
@@ -1 +1 @@
-{"COMIRNATY": 5.133015970635388, "SPIKEVAX": 1.7358780501614377}
\ No newline at end of file
+{"null": 0.8367884313441496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/153.json
index 47fc6025441..4f7cb8d6fae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/153.json
@@ -1 +1 @@
-{"BONVIVA": 1200.2870037727855}
\ No newline at end of file
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1530.json
index 4a092825328..beb401d3ede 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1530.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1530.json
@@ -1 +1 @@
-{"APIDRA": 1.0025152690522054, "AVANDAMET": 34.3377536578613, "AVANDIA": 28.280664935486307, "BONVIVA": 1.2422553795661844, "CASPOFUNGIN": 1.7240311228780882, "COMBIVIR": 1.2453847934344353, "COMIRNATY": 1.615123244523247, "EDOXABAN": 14.125312279002154, "EVENITY": 1.1537551342621943, "FAMPYRA": 1.2885925075631064, "FORSTEO": 1.039483886681613, "ICLUSIG": 2.010681025695614, "KYPROLIS": 2.125939971835359, "LEVOFLOXACIN": 1.1051507599013075, "ONGLYZA": 56.45751122080873, "RELVAR": 1.3022162889912448, "ROACTEMRA": 1.0033919170490473, "ROSIGLITAZONE": 15.261591344174978, "SHINGRIX": 1.5356982979647715, "TASIGNA": 1.890239698861785, "TWINRIX": 1.5123207947342203, "VAXZEVRIA": 1.49972881188296, "VIAGRA": 1.271181861258729, "null": 1.5409578519055538}
\ No newline at end of file
+{"AVAMYS": 101.19851193715763, "KEYTRUDA": 5.584270196631741, "OCALIVA": 653.362880489703, "null": 0.3565175758261997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1531.json
index a0bc87b854b..c9149709361 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1531.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1531.json
@@ -1 +1 @@
-{"CYMBALTA": 1.6073413174270537, "DEXAMETHASONE": 8.870738848548678, "ENTRESTO": 3.683105492181041, "JANUVIA": 2.7951852559606523, "MIDAZOLAM": 7.11352083653256, "OPSUMIT": 2.3552956199796875, "RASBURICASE": 168.13610249659004, "ROACTEMRA": 9.13666196492407, "null": 1.5226020104915738}
\ No newline at end of file
+{"COMIRNATY": 0.1969566100509166, "SOLIRIS": 14.828594614505556, "XOFIGO": 168.1925427076586, "null": 0.4688208326451144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1532.json
index c246015b956..0b737452ac6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1532.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1532.json
@@ -1 +1 @@
-{"COMIRNATY": 2.4455259787017978, "SPIKEVAX": 1.953177568060083}
\ No newline at end of file
+{"ABACAVIR": 1.2537485406079576, "ABILIFY": 0.2361506414914655, "ACTOS": 2.145073842746214, "AFINITOR": 1.5385044623341717, "ALEMTUZUMAB": 0.8719147329521485, "ALIMTA": 1.7208317195612248, "ALOXI": 11.42816061559514, "AMIKACIN": 1.2298559473061583, "AMINOSALICYLIC": 1.2463078198579214, "ANAKINRA": 0.9372820426395004, "APREPITANT": 0.8803037865368187, "APROVEL": 1.503087851483305, "APTIVUS": 10.626364852276328, "ARAVA": 0.7985971169392752, "ARIPIPRAZOLE": 1.2960940563749634, "ARIXTRA": 3.456069793688746, "ASPARAGINASE": 3.5001837360849595, "ATAZANAVIR": 1.3341027525833709, "ATRIPLA": 0.1238372375491119, "AUBAGIO": 0.6640833826676665, "AVANDIA": 2.3835883387006183, "AVASTIN": 1.0502644207469911, "AXITINIB": 1.453127745821816, "AZATHIOPRINE": 1.2912876249099103, "BARACLUDE": 6.223079080843263, "BASILIXIMAB": 2.0495281416641, "BEDAQUILINE": 1.629802327852791, "BETAFERON": 1.1732241108484915, "BEVACIZUMAB": 1.332540158322172, "BIKTARVY": 0.5747960437211371, "BRAFTOVI": 0.9450799713132692, 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3.31284119327257, "OCALIVA": 26.190048824191013, "OFEV": 1.1680945551929376, "OLANZAPINE": 1.1274467908437094, "OLYSIO": 2.070767466038057, "OPDIVO": 1.036833391174093, "OPSUMIT": 0.905373540801492, "ORKAMBI": 1.9851108393921963, "PACLITAXEL": 1.4040424373264069, "PANTOPRAZOLE": 1.9569994396196784, "PAZOPANIB": 2.1979120649952697, "PEGASYS": 0.6848677059157949, "PEGINTERFERON": 0.9293497812804428, "PEGINTRON": 0.3969776048935759, "PEMBROLIZUMAB": 0.5807008886679151, "PLAVIX": 0.9452453792363282, "PREGABALIN": 0.8077382749016452, "PREOTACT": 23.79542210462477, "PROTELOS": 5.092025947720859, "RAPAMUNE": 1.1477465115871808, "RASILEZ": 1.0049549425206583, "REMDESIVIR": 3.681850794248125, "REYATAZ": 2.1974001787726, "RIBOCICLIB": 4.309969433314161, "ROACTEMRA": 0.4777554531196354, "RUBRACA": 2.566268309356594, "SOLIRIS": 0.5688173669085634, "SOMATROPIN": 3.775187826782616, "SPIKEVAX": 0.0124450990061162, "STELARA": 0.2907218054589445, "STIVARGA": 2.4160293558668413, "STOCRIN": 10.51552654387456, "SUTENT": 0.9297132611928648, "TAGRISSO": 0.547338413541149, "TAMIFLU": 1.5578702045518402, "TASIGNA": 1.7471998841476404, "TENOFOVIR": 2.867471441805755, "TOBRAMYCIN": 2.270878993529436, "TORISEL": 3.923368540893705, "TOZINAMERAN": 0.0817307798869914, "TRACLEER": 22.12681368373806, "TRULICITY": 0.3942826782508128, "TRUVADA": 0.164504222854163, "VAXZEVRIA": 0.0072752863977314, "VFEND": 10.306379197647791, "VIRAMUNE": 3.955033721033424, "VIREAD": 1.1937158370607956, "VORICONAZOLE": 7.136350447736459, "VOTRIENT": 2.570788700297784, "XALKORI": 2.523291377501947, "XELJANZ": 0.1400707054241266, "XOFIGO": 8.511961997703326, "XOLAIR": 0.2056714290101515, "XTANDI": 0.4598161108930421, "YONDELIS": 7.09801570466784, "ZOMETA": 2.9294284995589384, "ZYPREXA": 3.062838422163804, "null": 2.104994699809715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1533.json
index 130008d877a..81df43205fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1533.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1533.json
@@ -1 +1 @@
-{"ELIQUIS": 30.37698521905501, "OPSUMIT": 6.732114424865575, "SILDENAFIL": 16.144124748598774, "TRACLEER": 5.413709178254137, "null": 1.5665178497318932}
\ No newline at end of file
+{"SPIKEVAX": 39.2133480753029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1534.json
index d7837123a8f..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1534.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1534.json
@@ -1 +1 @@
-{"COMIRNATY": 4.956730160555961, "SPIKEVAX": 1.8072448992757093, "TOZINAMERAN": 4.204783700666646}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1535.json
index 3d60648331f..8aa231bf280 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1535.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1535.json
@@ -1 +1 @@
-{"COMIRNATY": 5.05061219477771}
\ No newline at end of file
+{"GARDASIL": 27.869754761488355, "null": 2.413403845081248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1536.json
index 5c218280589..acfe7238125 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1536.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1536.json
@@ -1 +1 @@
-{"null": 2.1384046678205544}
\ No newline at end of file
+{"null": 2.386097647336676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1537.json
index 7b4697c2d6e..01ff81e6902 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1537.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1537.json
@@ -1 +1 @@
-{"null": 4.198178255655119}
\ No newline at end of file
+{"null": 2.8296882371942016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1538.json
index 93d9bd31879..f1e724f8d20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1538.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1538.json
@@ -1 +1 @@
-{"ACLIDINIUM": 69.48812564852915, "BIKTARVY": 30.269188311999528, "CLOPIDOGREL": 5.114031608264401, "ELIQUIS": 2.514351555136754, "ICLUSIG": 47.80376620813438, "TASIGNA": 34.89484449192835, "ZOSTAVAX": 4.153971721405801}
\ No newline at end of file
+{"null": 1.6305801185912183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1539.json
index 99ff49c544e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1539.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1539.json
@@ -1 +1 @@
-{"AVANDAMET": 34.88417120150129, "AVANDIA": 32.31122725560829, "ELIQUIS": 4.375704885111605, "TASIGNA": 12.284041145271209, "VIAGRA": 12.715402064002356, "ZOSTAVAX": 7.161937981930075, "null": 1.0930621755290784}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/154.json
index a1c098d256a..285faf3af38 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/154.json
@@ -1 +1 @@
-{"null": 2.1983590768470163}
\ No newline at end of file
+{"BEVACIZUMAB": 12.306730400452308, "COMBIVIR": 24.0434142335154, "CRIZOTINIB": 302.8494243972876, "DASATINIB": 74.04215963479666, "DOXORUBICIN": 33.07876840221489, "ERLOTINIB": 1461.8004258303438, "FULVESTRANT": 15.660106917405516, "GEFITINIB": 1332.9235146927251, "IRESSA": 69.7042989401872, "LAMIVUDINE": 33.238896139176376, "OSIMERTINIB": 1267.3087728740286, "TAGRISSO": 14.86060427971434}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1540.json
index e9aa43fc22a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1540.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1540.json
@@ -1 +1 @@
-{"COMIRNATY": 3.091901208942295}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1541.json
index 9e9d34e705e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1541.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1541.json
@@ -1 +1 @@
-{"APIXABAN": 144.15541599236258, "AVANDIA": 5.520725541068261, "BYDUREON": 4.771356287771768, "CLOPIDOGREL": 2.514811233509634, "ELIQUIS": 2.297783335098017, "HUMALOG": 5.610036303401736, "LANTUS": 2.081038859188506, "PLAVIX": 7.949387345977489, "TASIGNA": 12.77430639400956, "ZOSTAVAX": 2.3278746787088505}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1542.json
index f27fdd25d62..ac51884abee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1542.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1542.json
@@ -1 +1 @@
-{"ARANESP": 3.039208306871444, "AVANDIA": 21.873323527850555, "CANNABIDIOL": 58.28750891002685, "CLOPIDOGREL": 3.115325471763392, "ELIQUIS": 3.1535009726382546, "ENTRESTO": 1.9875924236454927, "EYLEA": 4.320024118545673, "FORSTEO": 2.284131476835194, "ICLUSIG": 18.05575825649166, "JARDIANCE": 2.047691992522021, "KALETRA": 5.318978865928611, "NILOTINIB": 48.48881012128784, "OPTIMARK": 4.771383072175496, "PLAVIX": 2.026510596699157, "SILDENAFIL": 8.654882544316697, "TASIGNA": 73.38479983987187, "ZOSTAVAX": 8.229210202647831}
\ No newline at end of file
+{"CICLOSPORIN": 17.352643913423993, "VFEND": 43.70566324897491, "null": 1.04496299129349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1543.json
index cfe194cc99e..95962237803 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1543.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1543.json
@@ -1 +1 @@
-{"ALISKIREN": 1761.9388493684608, "VAXZEVRIA": 1.5322322025445856}
\ No newline at end of file
+{"JARDIANCE": 33.38340919867413, "null": 1.6679598926299606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1544.json
index 78f17e79bd5..e89e41acd5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1544.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1544.json
@@ -1 +1 @@
-{"ZOSTAVAX": 19.786381317737995, "null": 2.002485545933019}
\ No newline at end of file
+{"ABACAVIR": 2.735628081751657, "ABILIFY": 9.099732145690057, "EXJADE": 5.665182473005377, "HYDROCORTISONE": 9.07703565732296, "IBUPROFEN": 6.452367242388922, "JARDIANCE": 3.3968292062894, "MIDAZOLAM": 11.683967862301108, "OLANZAPINE": 3.054370859105473, "SPIRONOLACTONE": 18.98393803184759, "TENOFOVIR": 55.16388215135517, "null": 2.073224031784142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1545.json
index 79d92a4fc76..d4a8f61a72c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1545.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1545.json
@@ -1 +1 @@
-{"null": 1.3193243928001126}
\ No newline at end of file
+{"null": 1.384762177544334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1546.json
index 62a0099409b..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1546.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1546.json
@@ -1 +1 @@
-{"COMIRNATY": 3.848447421051007}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1547.json
index c2dd2b22ffe..35c05d41dae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1547.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1547.json
@@ -1 +1 @@
-{"JANUMET": 21.718846123530312, "JANUVIA": 43.69653346331915, "LANTUS": 7.631887366467426, "ZOSTAVAX": 8.206074668850489}
\ No newline at end of file
+{"null": 1.0694489479752738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1548.json
index 30230893057..d627281314c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1548.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1548.json
@@ -1 +1 @@
-{"ACLASTA": 30.76741645086172, "APIXABAN": 96.6988922946502, "AUBAGIO": 6.677327134410737, "AVONEX": 18.056008123809608, "BYDUREON": 3.856835323588883, "BYETTA": 2.909981130563528, "CICLOSPORIN": 1.1408768102684426, "CIMZIA": 2.580782422396769, "DULOXETINE": 6.568388078457318, "ELIQUIS": 4.060750994182974, "ENBREL": 7.316151262467264, "ESOMEPRAZOLE": 4.559309149915089, "EXFORGE": 1.381296151897069, "FASLODEX": 2.225862990347349, "HUMALOG": 4.593000472920966, "HUMIRA": 3.300463452940652, "JANUMET": 1.2681386121040052, "LANTUS": 2.30440753332616, "LYRICA": 1.4320758124671962, "METHOTREXATE": 1.7009655987733892, "NAGLAZYME": 14.148462967139364, "OCEAN": 134.7226658250234, "OMALIZUMAB": 2.730412040789913, "PEMBROLIZUMAB": 1.729006221562298, "SIMPONI": 3.76397920449278, "STELARA": 1.5827494008019334, "SUBOXONE": 1.195849066450607, "TREMFYA": 2.3581734268940098, "XELJANZ": 4.703984029745597, "ZOSTAVAX": 8.274418285922948}
\ No newline at end of file
+{"ADENURIC": 53.80976153772515, "AFINITOR": 7.802089445957797, "JAKAVI": 9.848901771880392, "KEYTRUDA": 3.345651308848639, "NEXAVAR": 4.833402952007588, "OCALIVA": 88.7207386379766, "OLYSIO": 54.23594779242484, "SOLIRIS": 12.1997425493231, "SUTENT": 3.5386493462540227, "null": 0.6282169156597258}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1549.json
index 6958ec59771..fd0abeb73bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1549.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1549.json
@@ -1 +1 @@
-{"ENBREL": 5.083033701045409, "LANTUS": 3.403557763170366, "TRUVADA": 1.9607274937648935, "XELJANZ": 4.889307878385795, "null": 1.2325194562571091}
\ No newline at end of file
+{"COMIRNATY": 0.1830545823067516, "null": 1.251088505365932}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/155.json
index 224a4dfccbb..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/155.json
@@ -1 +1 @@
-{"COMIRNATY": 2.353703880402512, "KEYTRUDA": 5.4238229641812215, "MEKINIST": 18.550491100071337}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1550.json
index 382f3807a3d..01a31a9da1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1550.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1550.json
@@ -1 +1 @@
-{"ATAZANAVIR": 59.106242291052055, "RITUXIMAB": 26.35375761621817}
\ No newline at end of file
+{"ABACAVIR": 0.7928107873767382, "ABEMACICLIB": 6.925106015555614, "ABILIFY": 0.4310667485619051, "ACLIDINIUM": 13.905472518328969, "AFINITOR": 1.231466607019989, "AGENERASE": 18.615332890126915, "ALEMTUZUMAB": 0.5658426985819636, "ALIMTA": 0.7139428161118804, "ALOXI": 9.843290135730951, "AMINOSALICYLIC": 0.5023518078486904, "ANORO": 0.8016573204191512, "APTIVUS": 17.35154857583515, "ARAVA": 0.3346423930794546, "ASPARAGINASE": 5.86583937435927, "ATAZANAVIR": 10.421517124373574, "ATRIPLA": 0.0383296452727996, "AUBAGIO": 0.6246603812284914, "AVANDIA": 2.208542461144458, "AVASTIN": 1.1677720788720658, "AXITINIB": 2.821124475125862, "AZACITIDINE": 1.1254053404457982, "AZATHIOPRINE": 1.600236564219737, "BARACLUDE": 4.681813342421798, "BEDAQUILINE": 2.5543675093740186, "BETAFERON": 1.567615907376938, "BEVACIZUMAB": 1.4137437056823914, "BIKTARVY": 0.6739957072755868, "BOSULIF": 0.9108293350116684, "BOSUTINIB": 3.984450331893605, "BRAFTOVI": 0.6689565040979433, "BRILIQUE": 0.3709957564182572, 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0.7633413798767027, "XELODA": 2.362730285734237, "XTANDI": 0.226565134996992, "YERVOY": 1.5057251926753807, "YONDELIS": 4.467904246632971, "ZELBORAF": 3.5236908294593285, "ZEPATIER": 3.230507347985777, "ZIAGEN": 2.7379674010269577, "ZYPREXA": 0.8975906062203227, "null": 1.3227036017707092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1551.json
index 9c65cbb71da..371a97d9e85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1551.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1551.json
@@ -1 +1 @@
-{"CICLOSPORIN": 26.39201935018955}
\ No newline at end of file
+{"SPIKEVAX": 52.109412659634685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1552.json
index 25ca1074c53..6b0c101582e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1552.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1552.json
@@ -1 +1 @@
-{"GARDASIL": 24.5973379204542, "XYREM": 484.90612104083385, "null": 1.206638088652392}
\ No newline at end of file
+{"CYTARABINE": 12.071573834927326, "EXJADE": 6.156810747961655, "KAFTRIO": 25.475155176632757, "KALETRA": 16.716819883680298, "REYATAZ": 91.59487959699156, "ROACTEMRA": 8.623810047461427, "TASIGNA": 16.729017198398083, "null": 1.03046585901905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1553.json
index fe75f44ea37..9fde10a136d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1553.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1553.json
@@ -1 +1 @@
-{"ACLIDINIUM": 10.95899860812604, "ACTOS": 6.792442457169299, "ACTRAPID": 1.295741133808034, "ALISKIREN": 21.68466296111506, "ANAKINRA": 2.676169655529511, "ANORO": 1.124547038277205, "APIDRA": 5.567179224070009, "APROVEL": 1.065619315304579, "AVAMYS": 1.869407899514045, "AZATHIOPRINE": 1.6028978322329857, "AZOPT": 7.815669624254697, "BEOVU": 4.149969651199775, "BORTEZOMIB": 1.1201619047889884, "BYDUREON": 4.15670668816539, "BYETTA": 3.0331457871395338, "CELLCEPT": 1.6930323574152175, "CIALIS": 1.932506862781869, "CIMZIA": 1.0446557119422255, "DEXAMETHASONE": 1.192622792144172, "DULAGLUTIDE": 2.9450859652712165, "DUPIXENT": 7.502553720239467, "ELIQUIS": 2.570693854505259, "ENBREL": 1.4989494352734498, "ENTYVIO": 2.1130708822086794, "ENZALUTAMIDE": 1.6858297015221904, "EVENITY": 1.5320255599812778, "EVISTA": 4.3228607882600665, "EXFORGE": 1.4286765015313367, "EXJADE": 1.2862482701579112, "EYLEA": 11.084338251543995, "FASLODEX": 1.1276176994995, "FLUTICASONE": 4.093470979272404, "FORSTEO": 2.2514456164716066, "GALVUS": 2.306374864559677, "HALAVEN": 1.012079403042189, "HUMALOG": 9.839782553755816, "HUMIRA": 2.7187448663556104, "HYDROCHLOROTHIAZIDE": 5.047155231959379, "HYDROCORTISONE": 3.04694164686073, "IBRANCE": 3.2750642879210643, "INCRUSE": 3.797578380517582, "INSULIN": 3.9344252892003713, "JANUMET": 1.862044616038876, "JANUVIA": 2.010877773722391, "KAFTRIO": 2.713989314188213, "LANTUS": 17.612958042832147, "LEVEMIR": 7.6274511904606035, "LYRICA": 1.0264779218128486, "MELATONIN": 1.6228427634014015, "MEPOLIZUMAB": 2.144824758490625, "METHOTREXATE": 1.352595037085985, "NEVANAC": 4.195486144769688, "NINLARO": 3.676902182580594, "NOT": 1.891818522983277, "NUCALA": 1.1130947272727172, "OMALIZUMAB": 1.6701798498607558, "ORKAMBI": 1.7123798053659012, "OXYBUTYNIN": 1.9222771698501149, "PROTOPIC": 13.546145947990938, "RAPAMUNE": 1.7200283628327064, "RASILEZ": 1.2164697476427573, "RELVAR": 1.967667326567278, "REVATIO": 3.0218606753069643, "REVLIMID": 1.9384241921405656, "RINVOQ": 1.1197597997542554, "RUCONEST": 1.8730686107705257, "SIMPONI": 2.623494442773684, "SPRYCEL": 1.1276979382232228, "STELARA": 1.5684723800684546, "TOUJEO": 7.476190820516678, "TOVIAZ": 2.5011124588853395, "TRELEGY": 4.940883649821618, "TRULICITY": 1.766234782287679, "VIAGRA": 4.892272306849099, "VICTOZA": 3.3927650197464114, "XELJANZ": 4.189898744413058, "XYREM": 1.027286681450598, "ZOMETA": 4.2491718357283785, "ZOSTAVAX": 7.046807611290622, "null": 1.412180488248573}
\ No newline at end of file
+{"BIKTARVY": 8.257055944504613, "CLOPIDOGREL": 1.626908978112371, "COMIRNATY": 0.3516142939479262, "ELIQUIS": 3.999958776315884, "NPLATE": 15.059613537086902, "PEGASYS": 1.8465895348851704, "PLAVIX": 1.9992610897933445, "SPIKEVAX": 0.2920378944608446, "SUTENT": 3.500253335141063, "TOZINAMERAN": 1.0674195629176573, "VAXZEVRIA": 1.2913568203792114, "XELJANZ": 1.164999597590636, "null": 1.0872582938858564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1554.json
index 9cceaab60de..f8ac2200cdb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1554.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1554.json
@@ -1 +1 @@
-{"null": 2.942808161658988}
\ No newline at end of file
+{"null": 0.8438068151165871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1555.json
index cd17f28997e..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1555.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1555.json
@@ -1 +1 @@
-{"ZOSTAVAX": 97.67816847681476}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1556.json
index 260dd13bc6f..3491cb4bf8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1556.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1556.json
@@ -1 +1 @@
-{"SHINGRIX": 10.838850829974946, "ZOSTAVAX": 182.8715189798205}
\ No newline at end of file
+{"VICTOZA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1557.json
index 2174d7ae5af..02f91e873ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1557.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1557.json
@@ -1 +1 @@
-{"ABATACEPT": 1.0402359273383794, "APIDRA": 4.741317706965829, "BENLYSTA": 3.2524693257018487, "BYETTA": 13.073975548849733, "CICLOSPORIN": 1.022325894054218, "ELIQUIS": 1.4703139733844492, "EYLEA": 33.26683624145024, "HUMALOG": 1.5025887435123138, "INCRUSE": 22.82100302744276, "INSULIN": 2.0101496829205883, "JANUMET": 11.27158413215527, "JANUVIA": 8.527728452256126, "LANTUS": 29.513441420001868, "LEVEMIR": 11.119449694123473, "MEPOLIZUMAB": 3.76089216217782, "TRELEGY": 6.5900996954939774, "VELTASSA": 8.733156986795626, "VICTOZA": 6.768444630570269, "VOTRIENT": 3.102775735170774, "ZOSTAVAX": 7.683389338662602, "null": 1.5375682322391162}
\ No newline at end of file
+{"CAPRELSA": 2023.5237525885243, "null": 0.3066760465565514}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1558.json
index 9b8cdd727f4..14a01fd8447 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1558.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1558.json
@@ -1 +1 @@
-{"null": 1.1050395043329635}
\ No newline at end of file
+{"FORSTEO": 11.403199381818732, "IRBESARTAN": 24.73191768451817, "MIMPARA": 155.49474724300757, "SUTENT": 2.57757354844122, "ZOSTAVAX": 4.66692952713714, "null": 1.7275004044524738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1559.json
index a851b147a20..2b5bbd29d70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1559.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1559.json
@@ -1 +1 @@
-{"APIDRA": 27.86075734754604, "DEXAMETHASONE": 15.365270294327734, "EYLEA": 27.34508598377765, "null": 1.131395614038364}
\ No newline at end of file
+{"ABILIFY": 1.5245783834426447, "ADALIMUMAB": 0.2109680603448764, "AFINITOR": 1.4703366240547864, "ALIMTA": 1.547419285551456, "AMBROXOL": 312.51976967612313, "AMINOSALICYLIC": 15.655533377231198, "AMLODIPINE": 264.26574021931714, "ATRIPLA": 0.5246391820553711, "BEDAQUILINE": 15.0832713668674, "CABOMETYX": 3.8874940996650063, "CAFFEINE": 189.47457383055595, "CAPRELSA": 16.183524073014254, "CEFUROXIME": 75.65609615152682, "CICLOSPORIN": 0.3936895444059906, "COMIRNATY": 0.0338236396198032, "CYTARABINE": 1.599156442331806, "DELAMANID": 28.8577423156231, "DEXAMETHASONE": 0.6654617356780272, "ELIQUIS": 0.2271884715563309, "ENTRESTO": 1.0513238116697377, "EVENITY": 13.234423592449104, "EXJADE": 6.663526877428926, "FENTANYL": 1.34874515563855, "FORSTEO": 2.4195198182046336, "IBRANCE": 3.066747693101661, "KEPPRA": 0.5908248903399593, "KEYTRUDA": 0.6660000445970419, "KYMRIAH": 5.421222115419543, "LEMTRADA": 1.9540788891391612, "LEVOFLOXACIN": 88.39815108032741, "MEKINIST": 1.2250993749550996, "MIDAZOLAM": 2.3048154479087346, "MIMPARA": 39.458404272688206, "NATPAR": 160.57237064988138, "OLANZAPINE": 0.895291192097505, "OPSUMIT": 1.2293858045229, "OZEMPIC": 19.00370063589676, "PEGASYS": 0.8668676244066176, "SOLIRIS": 3.178532224479821, "SPIKEVAX": 0.0915666438785589, "SUTENT": 1.9480251432860245, "TOZINAMERAN": 0.1170018111013121, "TRUVADA": 0.727015443536749, "VENETOCLAX": 5.576604509235185, "XTANDI": 1.247426626602811, "ZOSTAVAX": 0.7366757230812543, "null": 1.1527496219809437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/156.json
index ed404b6f6c4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/156.json
@@ -1 +1 @@
-{"FENTANYL": 140.24359105862902, "null": 1.1646108727749316}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1560.json
index 28aec6f779a..4593734df7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1560.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1560.json
@@ -1 +1 @@
-{"ADALIMUMAB": 10.963822457919322, "BENLYSTA": 4.284805757933276, "COMIRNATY": 1.004332767352402, "COVID19": 1.011767003287798, "MMRVAXPRO": 18.710368379659894, "RELVAR": 26.42466552980598, "SIMPONI": 3.1217104386428955, "SUTENT": 1.127369703222704}
\ No newline at end of file
+{"ACLIDINIUM": 9.75717599082466, "AFINITOR": 2.340143614196821, "ARANESP": 9.825026634024846, "BONVIVA": 5.643798392857228, "BUDESONIDE": 20.54637399970606, "BYETTA": 1.813403089470724, "CARFILZOMIB": 13.515864915300591, "CLOPIDOGREL": 0.961523408786736, "COMIRNATY": 0.0358560417302013, "CYMBALTA": 0.4259680122027324, "DENOSUMAB": 21.03030882339737, "EVENITY": 8.554528081514452, "EVISTA": 5.669521243400619, "FASLODEX": 1.5543930356195996, "FORSTEO": 45.7803592108281, "HUMALOG": 0.6590685414803156, "IBRANCE": 2.0531534403148566, "INLYTA": 3.3685091442003534, "LEVOFLOXACIN": 2.659245518796691, "MEKINIST": 2.576540460546397, "MIMPARA": 74.11910324376421, "NUCALA": 3.1128842172760964, "PREOTACT": 121.49477305195362, "SUTENT": 2.3028050684551964, "TIVICAY": 10.782368581468528, "XELJANZ": 0.5725798038209494, "XTANDI": 1.075277231438423, "null": 1.690391119877601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1561.json
index 86192e5b1dd..ee4903b8f2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1561.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1561.json
@@ -1 +1 @@
-{"ABILIFY": 3.995800109314074, "ARIPIPRAZOLE": 28.410243610143063, "CHAMPIX": 1.4837549650653783, "DEXMEDETOMIDINE": 50.98857888655453, "KEPPRA": 4.751637999039611, "LATUDA": 13.731708102417722, "OLANZAPINE": 47.71680434909285, "RISPERIDONE": 22.139566954908773, "ZYPREXA": 14.01385406055225, "null": 1.8819313478381527}
\ No newline at end of file
+{"SPIKEVAX": 18.937175715182267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1562.json
index 8c1c97efeee..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1562.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1562.json
@@ -1 +1 @@
-{"null": 2.693428309169082}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1563.json
index 49cdd615d81..e3c5b231789 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1563.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1563.json
@@ -1 +1 @@
-{"OPSUMIT": 215.6054822398508, "TRACLEER": 79.899170970412, "null": 1.239252756897759}
\ No newline at end of file
+{"null": 2.350687498794147}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1564.json
index 741e59f0c5d..ccb20814a20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1564.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1564.json
@@ -1 +1 @@
-{"ELIQUIS": 3.1776154255171325, "JANUMET": 6.177573232899661, "JANUVIA": 8.292377821636826, "LANTUS": 2.0127790951034816, "OPSUMIT": 51.99438268895771, "TRACLEER": 28.57035584100068, "null": 1.285601756129905}
\ No newline at end of file
+{"null": 1.0088296720616217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1565.json
index e5db35ed6bd..b2ac141f0f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1565.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1565.json
@@ -1 +1 @@
-{"OPSUMIT": 45.30606075588232, "null": 1.932247952740592}
\ No newline at end of file
+{"BEDAQUILINE": 41.89213916216588, "CELECOXIB": 35.98760026635491, "COMIRNATY": 0.085418460713596, "DELAMANID": 42.32635729167484, "EMEND": 33.369018037201094, "ENTRESTO": 4.229118504721679, "EXJADE": 6.042427153229768, "MICARDIS": 11.732202933256296, "OLANZAPINE": 3.00257387899385, "SPIKEVAX": 0.1153189739127099, "ZYPREXA": 2.3126415676723826, "null": 1.930996605997128}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1566.json
index d519e397d09..e03f323a762 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1566.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1566.json
@@ -1 +1 @@
-{"NAGLAZYME": 596.0261588194577}
\ No newline at end of file
+{"BEDAQUILINE": 16.422352830707872, "CARBIDOPA": 66.84599916920449, "COMIRNATY": 0.0676467997050847, "ENTRESTO": 16.278540927303148, "EXJADE": 13.48837494653984, "KYMRIAH": 10.89032492788458, "LACOSAMIDE": 59.27522587770058, "LEVETIRACETAM": 104.64334134233098, "OLANZAPINE": 3.091714873270928, "SPIKEVAX": 0.1474240611163279, "TOZINAMERAN": 0.5019105703386351, "null": 0.7357012679143725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1567.json
index eac489ff155..0f7cc9ca911 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1567.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1567.json
@@ -1 +1 @@
-{"null": 1.2418534197614348}
\ No newline at end of file
+{"SPIKEVAX": 36.8236670946199}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1568.json
index a8da2a48f02..107b3596a70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1568.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1568.json
@@ -1 +1 @@
-{"AMBRISENTAN": 103.27590703428268, "OPSUMIT": 87.15336672724418, "TRACLEER": 45.369781943060254, "null": 2.026050891556175}
\ No newline at end of file
+{"ABATACEPT": 12.160286065646591, "ADALIMUMAB": 13.54536066986797, "BELIMUMAB": 502.00280067980657, "CLOPIDOGREL": 35.421811383094706, "null": 0.6479707125485153}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1569.json
index 7fa673bafa5..b4c9d096b37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1569.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1569.json
@@ -1 +1 @@
-{"OPSUMIT": 158.12701944966307, "null": 1.0020279253073698}
\ No newline at end of file
+{"ARAVA": 0.2685371967864056, "BELIMUMAB": 60.07266253242842, "BENLYSTA": 3.3069041875687133, "BYDUREON": 3.732671193689254, "COMIRNATY": 0.027373934414446, "CYMBALTA": 1.237402602066062, "GLYCOPYRRONIUM": 34.820862400272105, "HUMALOG": 1.0142983737147733, "JANUMET": 7.8496324071896355, "JANUVIA": 3.6104248793646816, "LANTUS": 0.8563652016152161, "MICARDIS": 7.818093217570179, "SOMAVERT": 125.68558345530217, "SUTENT": 1.358717375095396, "XELJANZ": 3.745472082769663, "ZOSTAVAX": 47.086650702910994, "ZYPREXA": 18.721964369663095, "null": 1.4433809472979715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/157.json
index a8aa914d16a..11c2c6c976e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/157.json
@@ -1 +1 @@
-{"CYTARABINE": 13.900643101419472, "DOCETAXEL": 10.784139793103844, "DOXORUBICIN": 22.85371684936645, "PACLITAXEL": 34.86832352491992, "RADIATION": 1435.2248209618683, "THIOTEPA": 80.76217224837043, "null": 2.0273906677297657}
\ No newline at end of file
+{"ALEMTUZUMAB": 18.86042173698703, "CANCIDAS": 36.188647529063, "CLOPIDOGREL": 9.33152821413186, "COMIRNATY": 0.8900280882085851, "ELIQUIS": 2.2239138630742104, "LANTUS": 1.9924556174862795, "PEGASYS": 3.138899803904076, "PLAVIX": 3.171888303539582, "SPIKEVAX": 0.3888013834651725, "TOZINAMERAN": 0.9082964250897, "VAXZEVRIA": 0.2290652972292119, "null": 0.5325532786432918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1570.json
index 93e834e664c..384a1c5d2d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1570.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1570.json
@@ -1 +1 @@
-{"ADCIRCA": 31.09215039085773, "ADEMPAS": 58.58749674255598, "CYTARABINE": 6.249086575690802, "NAGLAZYME": 32.256401947237606, "OPSUMIT": 88.63810958396907, "REVATIO": 13.674166652125068, "TRACLEER": 45.78843151475421, "YONDELIS": 82.19907633765617, "null": 2.0934306015453608}
\ No newline at end of file
+{"DENOSUMAB": 127.25585428435734, "PLAVIX": 6.073338111673948, "null": 1.6120566335216608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1571.json
index fe698a5ba18..b40d9253b2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1571.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1571.json
@@ -1 +1 @@
-{"null": 3.52619349075127}
\ No newline at end of file
+{"ABACAVIR": 2.265947060175652, "ABATACEPT": 15.94880599594087, "ABILIFY": 0.930729646004102, "ACTOS": 1.300847845755472, "ADALIMUMAB": 20.70148800325906, "AFINITOR": 2.512456270254482, "AIMOVIG": 1.6063343311197062, "AMINOSALICYLIC": 3.5520433046379, "ANAKINRA": 0.9495437336363136, "APREMILAST": 21.31229026981577, "APREPITANT": 3.198187677916212, "ARANESP": 20.11094953059278, "ARAVA": 7.327541659709261, "ARIPIPRAZOLE": 1.7975933196004223, "ASPARAGINASE": 0.5858527412857143, "ATRIPLA": 0.0837668642690928, "AUBAGIO": 0.4307466378431389, "AVANDAMET": 0.9943337468831032, "AVANDIA": 0.925274558616693, "BEXTRA": 6.180819101429842, "BIKTARVY": 1.5477976840269954, "BRAFTOVI": 0.4608025560640629, "BUDESONIDE": 0.1136241000225956, "BUMETANIDE": 2.059448774912401, "BYDUREON": 1.113232557922569, "BYETTA": 2.511166869299345, "CELECOXIB": 2.949996876689563, "CELLCEPT": 0.5569528907609509, "CHAMPIX": 0.3120884023149504, "CIALIS": 1.6837239344797008, "CICLOSPORIN": 0.5237305010780405, "CIMZIA": 1.9846321710986348, "CLOPIDOGREL": 0.3414241990940047, "COMBIVIR": 1.2894969249336714, "COMIRNATY": 0.059975369946937, "COSENTYX": 1.057286319776427, "CRIXIVAN": 2.759406209726458, "CYMBALTA": 0.7027538079278342, "DARBEPOETIN": 15.308342187836574, "DARUNAVIR": 5.441091785304298, "DESCOVY": 3.451725268989537, "DULOXETINE": 1.1936801707491171, "EFAVIRENZ": 1.3548481825612366, "ELIQUIS": 0.2365313323578084, "ENBREL": 0.8313346414898636, "ENTRESTO": 0.8846339456927376, "ERLEADA": 1.819558700226044, "ESBRIET": 0.3812051683167569, "ESMYA": 3.48969124913066, "ESOMEPRAZOLE": 1.2418939320814113, "EVISTA": 2.5507676414002893, "EXFORGE": 1.9874671187679185, "FASENRA": 0.5614115108406907, "FASLODEX": 0.4732198771841693, "FENTANYL": 0.1368536366476636, "FORSTEO": 2.6659602824308366, "FORXIGA": 0.8601970332945086, "GALVUS": 2.007822744440191, "GENVOYA": 2.805383525788392, "HUMALOG": 1.0546011816718404, "HUMIRA": 1.7657375652613103, "HYDROCORTISONE": 0.4496632435756158, "IBRANCE": 0.2090089042488881, "IBUPROFEN": 0.2399384160823496, "ICLUSIG": 0.7992416702199858, "INSULIN": 0.8064788124380747, "INTELENCE": 5.019847277198758, "INVIRASE": 3.8154871284687326, "ISOPHANE": 5.851026675786622, "JAKAVI": 1.1288460466496184, "JANUMET": 2.7938478228699704, "JANUVIA": 1.142030689164916, "JARDIANCE": 0.3727870979218076, "KALETRA": 1.5430190072367729, "KEPPRA": 0.3744762942520758, "KEYTRUDA": 0.0637975492266506, "LANTUS": 0.2694035825350701, "LATUDA": 0.8456952653542703, "LEFLUNOMIDE": 2.112261464991856, "LYRICA": 1.91025662218052, "MELATONIN": 2.1411486427712, "METHOTREXATE": 0.5283559826602446, "MYCOPHENOLATE": 1.7735696990094505, "NEVIRAPINE": 2.4965651509278355, "NUCALA": 0.1866248764359163, "OLANZAPINE": 1.6523662738757978, "OMALIZUMAB": 1.036962128181688, "PANTOPRAZOLE": 0.5286430286062367, "PEGASYS": 0.1953947636893902, "PEGINTRON": 0.1202564962023216, "PLAVIX": 0.3637981400112767, "PREGABALIN": 0.4898535638324652, "RAPAMUNE": 2.7404945975311823, "REMICADE": 0.7343218035927571, "RINVOQ": 5.692191286036434, "RITUXIMAB": 1.666934535323941, "ROACTEMRA": 4.131502110766711, "SAXENDA": 0.417926959632815, "SHINGRIX": 0.1721917715411778, "SIMPONI": 0.4872810256856597, "SPIKEVAX": 0.0161256925109835, "SPRYCEL": 0.3458892061850726, "STELARA": 0.4415714102891193, "STRIBILD": 0.1604134311785225, "SUTENT": 0.5585238867168677, "SYMTUZA": 5.4785669164247714, "TASIGNA": 1.20469243032312, "TORISEL": 1.994143507053708, "TOZINAMERAN": 0.1545584522898762, "TRULICITY": 0.3932766126007876, "TRUVADA": 0.0955796012333762, "VAXZEVRIA": 0.0238955499488705, "VIAGRA": 2.724478952654246, "XELJANZ": 4.251765446854117, "XOLAIR": 0.938370272967199, "XTANDI": 0.215619381611774, "XYREM": 1.3289877847744245, "ZOSTAVAX": 3.8456419806025752, "ZYPADHERA": 0.6234672029938556, "ZYPREXA": 7.148705009319468, "null": 0.7292408474240325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1572.json
index 53943c9441b..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1572.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1572.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 27.212191085595364, "PLAVIX": 79.02445855326559}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1573.json
index ee439b6943b..309724f5330 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1573.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1573.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 6.992388416708983, "ELIQUIS": 7.475241684036214, "OPSUMIT": 34.06766858394086, "PLAVIX": 7.309961457209004, "TRACLEER": 14.83711954210299, "null": 1.850052661774371}
\ No newline at end of file
+{"COMIRNATY": 0.2380547759820756, "null": 3.104327950416385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1574.json
index 4ec8a3894c9..36546c21d4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1574.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1574.json
@@ -1 +1 @@
-{"ADCIRCA": 23.725707624537367, "ADEMPAS": 37.15445880914137, "FILGRASTIM": 25.24170152175138, "OPSUMIT": 66.03319479758315, "REVATIO": 13.248195541234816, "SOLIRIS": 9.41449924980452, "TRACLEER": 38.86993871788317, "null": 1.4609758294388238}
\ No newline at end of file
+{"null": 2.0939884754270013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1575.json
index b3bd4a9546f..96694cd286c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1575.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1575.json
@@ -1 +1 @@
-{"null": 1.0215285781228296}
\ No newline at end of file
+{"AFINITOR": 51.07617925634806, "null": 2.4660225501760302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1576.json
index 61775fbeb63..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1576.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1576.json
@@ -1 +1 @@
-{"OPSUMIT": 136.5100199846976, "null": 1.861303764855476}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1577.json
index e2998e36555..6fe24368e39 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1577.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1577.json
@@ -1 +1 @@
-{"null": 1.609848241428752}
\ No newline at end of file
+{"null": 1.2052786277837375}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1578.json
index c6a6024788e..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1578.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1578.json
@@ -1 +1 @@
-{"ADCIRCA": 58.61882840648245, "CYTARABINE": 7.261041774239043, "METHOTREXATE": 13.634770004585016, "NAGLAZYME": 63.43451235684668, "OPSUMIT": 66.7711346235791, "SOLIRIS": 5.938609232789995, "TRACLEER": 28.16796955420939, "null": 1.497680535948859}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1579.json
index 7403a8a906e..40fee4fb1b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1579.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1579.json
@@ -1 +1 @@
-{"OPSUMIT": 152.28657713147533, "TRACLEER": 18.204207325980374, "null": 1.9254032749266328}
\ No newline at end of file
+{"KEYTRUDA": 23.01939993595458, "null": 0.7722266379170711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/158.json
index 7a7dd2852af..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/158.json
@@ -1 +1 @@
-{"CHAMPIX": 8.98584171860406, "CYMBALTA": 1.018699883024698, "KEPPRA": 9.31230073203831, "LEVETIRACETAM": 12.312738919978113, "LEVOFLOXACIN": 4.078748428537944, "OLANZAPINE": 5.765437993356041, "PEGASYS": 3.270185807663208, "PEGINTRON": 5.606059565663121, "RISPERIDONE": 17.990680499979902, "ZYPREXA": 5.174574349681914, "null": 1.8998453682186909}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1580.json
index a5dda1af24e..1b39b1cbe6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1580.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1580.json
@@ -1 +1 @@
-{"OPSUMIT": 94.49781077549986, "null": 1.8120328376136676}
\ No newline at end of file
+{"ATAZANAVIR": 54.71832424687673, "BUDESONIDE": 13.213170241211804, "KEYTRUDA": 32.04472163339069, "OPDIVO": 62.27091645409207, "null": 1.018505248132595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1581.json
index 9fb9c47a947..4116a217ae8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1581.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1581.json
@@ -1 +1 @@
-{"OPSUMIT": 29.90964209968053, "null": 1.1486183957103515}
\ No newline at end of file
+{"KEYTRUDA": 31.932085518528627, "null": 1.1469909579915067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1582.json
index 78b12a42423..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1582.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1582.json
@@ -1 +1 @@
-{"ADCIRCA": 105.13386574166655, "NAGLAZYME": 60.489012398999606, "OPSUMIT": 61.04922292827579, "TRACLEER": 54.724099387738335, "null": 1.4336301102960858}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1583.json
index abd9c33c0b4..0ca02180bdd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1583.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1583.json
@@ -1 +1 @@
-{"null": 2.158702033383775}
\ No newline at end of file
+{"null": 0.6468042779807913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1584.json
index 4f5c17f6b95..3d6d5ffe077 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1584.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1584.json
@@ -1 +1 @@
-{"null": 1.4952410478645848}
\ No newline at end of file
+{"null": 0.3623380263389641}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1585.json
index ea8de872d55..4104ee845b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1585.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1585.json
@@ -1 +1 @@
-{"null": 2.844207717923794}
\ No newline at end of file
+{"ABACAVIR": 1.3960511230350103, "AFINITOR": 1.790069642609352, "ARAVA": 0.2169248264620257, "ATRIPLA": 4.103640089140098, "CICLOSPORIN": 1.381799088453484, "CLOPIDOGREL": 1.8342703870593475, "COMIRNATY": 0.0892601400406057, "DENOSUMAB": 20.313165597450908, "ENTRESTO": 13.36585830485748, "EXJADE": 2.4061117849041787, "FORXIGA": 11.180521567494935, "IBRANCE": 0.9599243387453964, "JARDIANCE": 3.139527680320352, "KEYTRUDA": 1.1068668064151712, "RASILEZ": 7.777418992279464, "REVATIO": 5.492073195898689, "STRIBILD": 3.9269584221099176, "SUTENT": 2.7522577917004902, "TRUVADA": 7.446884595025429, "XELJANZ": 0.7032542562009033, "null": 1.0284794429239257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1586.json
index a3fd1546c50..ce897272436 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1586.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1586.json
@@ -1 +1 @@
-{"AVANDAMET": 21.67903078095096, "AVANDIA": 27.96274938235936, "BYETTA": 5.082865079975116, "ELIQUIS": 2.246324974374478, "HIZENTRA": 5.835808709415831, "JANUMET": 3.061587782552317, "JARDIANCE": 4.015816800054126, "LANTUS": 2.1533918040150595, "OPSUMIT": 28.22678027353397, "SYNAGIS": 7.862698151945158, "TRACLEER": 19.746812608045573, "TRELEGY": 6.094726808339167, "ZOSTAVAX": 3.487179841369404, "null": 1.5812013449491114}
\ No newline at end of file
+{"null": 2.5676189305704726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1587.json
index 0ab7aec3506..a3e798cef15 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1587.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1587.json
@@ -1 +1 @@
-{"OPSUMIT": 32.37743745352398, "SPIKEVAX": 1.586368010700223, "null": 1.4575876932770813}
\ No newline at end of file
+{"null": 1.6077607109363805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1588.json
index 6f593b31829..743303639d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1588.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1588.json
@@ -1 +1 @@
-{"BUPIVACAINE": 182.106144403854, "null": 2.452575989619478}
\ No newline at end of file
+{"COMIRNATY": 0.7667841833210026, "HEPSERA": 37.52840267058623, "KEYTRUDA": 2.08882233605587, "OLANZAPINE": 3.908400687776729, "ZYPREXA": 2.370075140237085, "null": 1.7421002536633152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1589.json
index 4fef92aa840..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1589.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1589.json
@@ -1 +1 @@
-{"APTIVUS": 2636.088350718861, "ARANESP": 38.94846739598081}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/159.json
index fcefce53af1..f343624302e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/159.json
@@ -1 +1 @@
-{"ALIMTA": 2.6168619496727743, "ATOSIBAN": 60.59716447575847, "AVANDAMET": 5.511566529707905, "AVANDIA": 6.5843825648219205, "BRIDION": 18.01519279076917, "BRILIQUE": 3.3698092643563604, "BYETTA": 1.3029233426033289, "CELLCEPT": 2.827860188455853, "CLOPIDOGREL": 1.878863920349496, "COMBIVIR": 3.1330727746349, "CYTARABINE": 1.8199840950806636, "DARZALEX": 5.268153293617144, "DEXAMETHASONE": 2.868006946523296, "ENTRESTO": 9.137260959862836, "FENTANYL": 5.019668337241424, "FORSTEO": 1.06733659270226, "FYCOMPA": 7.313833577725554, "JAKAVI": 1.5748289354919762, "KYPROLIS": 18.695398726695792, "LANTUS": 1.1673851342087431, "MIDAZOLAM": 7.090307550211025, "MULTAQ": 4.294321954024987, "NEXAVAR": 1.6589551546098509, "OLANZAPINE": 2.4004492326908715, "PLAVIX": 1.0256250848188724, "PREGABALIN": 2.921651623425848, "PRIVIGEN": 6.1841997790620615, "SOLIRIS": 2.366473995716444, "SPRYCEL": 4.703200832599902, "SUFENTANIL": 8.897214010958006, "SUTENT": 1.112948842863165, "TRACLEER": 1.905962121605143, "TRACTOCILE": 303.8077193865649, "VYXEOS": 42.04640313285206, "null": 1.5993078926716184}
\ No newline at end of file
+{"ATRIPLA": 4.597678262491591, "BIKTARVY": 23.28897853761737, "COMIRNATY": 0.4202882663663535, "ISENTRESS": 65.5802673297462, "KALETRA": 61.78128357706783, "VIAGRA": 11.27570503361228, "null": 0.5527519808745235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1590.json
index 35cf00a8a85..4df286f3a45 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1590.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1590.json
@@ -1 +1 @@
-{"COVID19": 2.262719745072532}
\ No newline at end of file
+{"null": 1.2263558701382549}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1591.json
index 2e34ffdafd0..8a09952142a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1591.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1591.json
@@ -1 +1 @@
-{"CANCIDAS": 18.21437716595152, "CELLCEPT": 3.772406021083672, "ELIQUIS": 2.001161259931424, "IRBESARTAN": 22.00405209910552, "KEPPRA": 6.621290721726646, "KISQALI": 11.223199500063604, "MEKINIST": 4.750027300384772, "METHOTREXATE": 2.701128564906756, "NORVIR": 34.658507580573975, "PEGASYS": 1.3263430016780826, "STIVARGA": 5.177619804681565, "VFEND": 6.7742683819065554, "VOTRIENT": 3.2183904173091102, "null": 1.2052624577678703}
\ No newline at end of file
+{"COMIRNATY": 0.721501295085641, "null": 1.0169085785986245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1592.json
index 65e3bac28cb..143f7d7112f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1592.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1592.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 63.48473717304628}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1593.json
index 04e27c2d3f4..8753f67a250 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1593.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1593.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 259.57356725092893}
\ No newline at end of file
+{"null": 0.7330776708644279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1594.json
index 0d7743406cc..3a167f2bdf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1594.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1594.json
@@ -1 +1 @@
-{"ABRAXANE": 2.494823195421424, "ACLIDINIUM": 3.005973076695175, "ADCIRCA": 1.3044653045430126, "AFINITOR": 2.1386922874364607, "ALIMTA": 2.0837567409464275, "AMBRISENTAN": 8.144903209767634, "ANAKINRA": 1.7142797627883808, "ANIDULAFUNGIN": 6.978286938413132, "ARIPIPRAZOLE": 3.0785430462790075, "ASPARAGINASE": 5.528754799572482, "AUBAGIO": 1.0560127136439876, "AXICABTAGENE": 6.827100509368127, "AZACITIDINE": 1.569782014897046, "AZATHIOPRINE": 1.6821539022314311, "BENLYSTA": 2.804685630571506, "BETAFERON": 4.31690922074272, "BEXSERO": 3.856011339805866, "BOSULIF": 1.377216616483958, "BUPIVACAINE": 1.4665322806936216, "BYDUREON": 2.53328242977071, "BYETTA": 1.419768631357574, "CANAKINUMAB": 27.599986625047823, "CARFILZOMIB": 2.381042815510983, "CASPOFUNGIN": 2.901197558477645, "CELLCEPT": 1.7769109592431025, "CIBINQO": 159.32369994182676, "CIMZIA": 2.0991154964834227, "CLOFARABINE": 7.785494328399304, "COMBIVIR": 2.235234738745988, "COSENTYX": 3.4703959725346887, "CUBICIN": 1.4412409790016727, "CYTARABINE": 1.635049491813232, "DAPTOMYCIN": 4.068436105211628, "DENOSUMAB": 2.3739034807456703, "DEXAMETHASONE": 2.495316253822397, "DULAGLUTIDE": 3.09051085911194, "DUPIXENT": 3.070157786095242, "ELIQUIS": 1.1833362100869298, "ENBREL": 1.242506997913238, "ENTYVIO": 2.261045036874991, "EPADERM": 51.347739721160735, "ERLEADA": 1.1766632273000996, "EVENITY": 1.3893823236023255, "EXJADE": 1.3499038860723476, "FASENRA": 1.0853924858160913, "FASLODEX": 1.5025297367699804, "FEBUXOSTAT": 2.1137575478070527, "FIRDAPSE": 1.7426554427124392, "GARDASIL": 1.532875016064186, "HALAVEN": 1.062048877293865, "HERCEPTIN": 1.079100114572049, "HIZENTRA": 5.166008982974264, "HUMALOG": 1.487564976835661, "HUMIRA": 1.8345983964336847, "HYQVIA": 3.293885050386294, "IBRANCE": 2.4487339498470786, "ILARIS": 29.26234992616037, "IMBRUVICA": 3.318917583278252, "INCIVO": 1.1299693414932084, "INVOKANA": 16.604928654713408, "JANUMET": 1.0141879422769962, "JANUVIA": 1.4075027253187944, "JARDIANCE": 1.3651260008868311, "JEVTANA": 3.11699386572926, "LANTUS": 1.2601235811837947, "LEFLUNOMIDE": 2.681727716739034, "LEVEMIR": 1.6789599556923889, "LYRICA": 1.0076718296582172, "MABTHERA": 1.1961668638173628, "MEKINIST": 1.165703380791005, "MELATONIN": 1.4213419680204613, "MENVEO": 14.478336598434163, "MEPOLIZUMAB": 1.692330742337311, "MERCAPTOPURINE": 1.95834181287414, "METFORMIN": 1.9781401369051217, "METHOTREXATE": 2.5520380525700643, "NEULASTA": 1.13803213292662, "NOT": 1.5538145704320117, "NPLATE": 1.8025373044161936, "OMALIZUMAB": 2.870984802543717, "OPSUMIT": 2.3842422031615835, "OPTIMARK": 1.5732967505652418, "ORENCIA": 5.055185786478892, "PEGASYS": 2.1801629576672634, "PEGINTERFERON": 1.7006676671002432, "PEGINTRON": 2.522573468139489, "PEMBROLIZUMAB": 1.0568455763832063, "PEMETREXED": 1.1255990102801852, "PREVENAR": 1.6600183754561868, "RAPAMUNE": 2.474994073095889, "REMICADE": 5.585064463023184, "REVATIO": 1.592352519953091, "REVLIMID": 1.566140241012354, "RINVOQ": 2.463731447863826, "RITUXIMAB": 2.4702574857767168, "ROACTEMRA": 6.728418253679414, "SHINGRIX": 4.505923853931332, "SIMPONI": 5.348614674958203, "SOLIRIS": 2.540578644706549, "SOMAVERT": 10.484020847367836, "SPRYCEL": 2.11163914374498, "STELARA": 4.3964861939240265, "TASIGNA": 1.2372332533481496, "THALIDOMIDE": 1.782740555782903, "TIVICAY": 1.9865113966315515, "TOCILIZUMAB": 7.70476162899105, "TOZINAMERAN": 1.1525490196384212, "TRACLEER": 1.9086092257487148, "TREMFYA": 6.41401529466631, "VELTASSA": 2.204686974173617, "VYXEOS": 9.518420207280547, "XELJANZ": 3.846776579850049, "XOFIGO": 1.181139443865701, "YERVOY": 1.3207488962353904, "ZOMETA": 2.6517937366580027, "ZOSTAVAX": 5.23092019367588, "ZYPREXA": 1.6073370608186388}
\ No newline at end of file
+{"ATRIPLA": 4.259964904495027, "CELLCEPT": 2.5585802054718263, "ELIQUIS": 3.738416962669119, "ENTRESTO": 3.678835301739419, "EXJADE": 5.858515577669999, "FORXIGA": 3.790608327679292, "INCIVO": 5.753007920460614, "JAKAVI": 5.2638655115579, "JANUMET": 2.973802257692256, "JARDIANCE": 1.8842222281512864, "KALETRA": 4.242064739075973, "KEYTRUDA": 3.5339809094165315, "SOLIRIS": 15.787918175425444, "STRIBILD": 7.6005497975066785, "SUTENT": 3.4523187163552587, "TRUVADA": 7.110318382294442, "VIREAD": 10.09269997643117, "VOTRIENT": 2.4498793095629003, "null": 0.6208506540713578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1595.json
index a8ffd76e09f..75ea3d6ff99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1595.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1595.json
@@ -1 +1 @@
-{"JARDIANCE": 101.29555790672087}
\ No newline at end of file
+{"ABILIFY": 4.441179664850091, "AFINITOR": 2.568502658340516, "AMINOSALICYLIC": 10.297877025771236, "ARIPIPRAZOLE": 3.4657063900104284, "ATRIPLA": 0.8276510478091889, "BEDAQUILINE": 43.18891062902315, "BEXTRA": 159.54988924297095, "CICLOSPORIN": 1.653338438961386, "COMIRNATY": 0.1051831295466007, "CYMBALTA": 0.9307893821641658, "ENBREL": 3.698381054108359, "ENTRESTO": 2.5258460839354218, "EXJADE": 7.373393112307101, "HUMIRA": 5.088663338530874, "IBRANCE": 1.7091235380890473, "JARDIANCE": 2.6037784865899867, "KEYTRUDA": 2.8284502325846046, "SOLIRIS": 5.04732889681092, "SUTENT": 1.7271889078113962, "null": 0.6633992421801413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1596.json
index 752d9e92b2b..ebecb7e6f9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1596.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1596.json
@@ -1 +1 @@
-{"null": 2.792889305099717}
\ No newline at end of file
+{"ABACAVIR": 0.2638574541606807, "ABATACEPT": 0.5304724888962801, "ABILIFY": 0.5970475388573875, "ABRAXANE": 0.9454473790855858, "ACLASTA": 1.2393474683102326, "ACLIDINIUM": 0.6013070404611917, "ACTOS": 1.0303884702444632, "ACTRAPID": 1.2363551941247797, "ADALIMUMAB": 0.2899577083800049, "ADCIRCA": 1.5035788617018675, "ADEFOVIR": 12.223504211243814, "ADENURIC": 1.5851963103742543, "ADVAGRAF": 4.260397932705378, "AFINITOR": 2.7728374384115635, "AGENERASE": 8.397804156873724, "ALEMTUZUMAB": 0.5321625807369182, "ALIMTA": 2.987016799152558, "ALISKIREN": 1.2867357195258995, "ALPELISIB": 2.401949180903367, "AMIKACIN": 1.5569689764644317, "AMINOSALICYLIC": 0.8320943790965366, "ANAKINRA": 0.4332920327205909, "ANTIBIOTICS": 1.260109401778735, "APIDRA": 0.2874877549509296, "APIXABAN": 0.7835755509356934, "APROVEL": 4.450656836076559, "ARANESP": 0.9329437205367788, "ARAVA": 0.2228856856061933, "ARIPIPRAZOLE": 0.678538320331686, "ASPARAGINASE": 0.4757826782798452, "ATAZANAVIR": 2.094927139699865, 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3.748518540921511, "JAKAVI": 1.3288913374746911, "JANUMET": 1.051420376722895, "JANUVIA": 0.785744768050184, "JARDIANCE": 1.9179926108418792, "JEVTANA": 0.653509620425895, "KALETRA": 2.2805696457474647, "KEPPRA": 0.260754161273311, "KEYTRUDA": 1.1769215705285945, "KISQALI": 2.1884418505127563, "KIVEXA": 2.252735372748044, "KYMRIAH": 0.3023580987503034, "KYPROLIS": 2.000381789456292, "LAMIVUDINE": 1.2663964235508414, "LANTUS": 0.3417608543841212, "LATUDA": 0.7770514241688644, "LEMTRADA": 0.5397245500305685, "LENVIMA": 1.1218762091106147, "LEVEMIR": 0.2322732961504275, "LEVETIRACETAM": 0.2876847367616675, "LEVOFLOXACIN": 1.054856772498442, "LIRAGLUTIDE": 1.3362019742819018, "LIXIANA": 0.8401782974415481, "LONSURF": 0.3290266446750761, "LOPINAVIR": 1.55205857524944, "LUPKYNIS": 11.126481027574018, "LYNPARZA": 2.731094829683042, "LYRICA": 0.9262719822012516, "MABTHERA": 0.3578808703417788, "MEKINIST": 0.7251631751573906, "MELPHALAN": 1.075896073138613, "MEMANTINE": 1.3173791786392963, 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"SPRYCEL": 0.4102770084401353, "STELARA": 0.3140647569039437, "STIVARGA": 0.6542756928603053, "STRIBILD": 6.959423137482869, "SUNITINIB": 1.6668211042574266, "SUTENT": 2.315285807699235, "TACROLIMUS": 3.813735773258565, "TAGRISSO": 0.7324862129540946, "TAMIFLU": 0.6012300898526481, "TASIGNA": 1.120127762352787, "TAXOTERE": 0.916904408608918, "TEKTURNA": 9.11414697954562, "TELAPREVIR": 20.323346852892215, "TELMISARTAN": 2.3743380964573357, "TENOFOVIR": 9.830290059793509, "THALIDOMIDE": 1.5093616226526925, "TICAGRELOR": 0.5033498399389768, "TIVICAY": 4.0523572205468845, "TOBRAMYCIN": 6.760496047570615, "TOCOPHEROL": 6.501998249629692, "TORISEL": 7.317667885973548, "TOVIAZ": 0.5779174985262976, "TOZINAMERAN": 0.0350390868818912, "TRACLEER": 0.7519218783631673, "TREMFYA": 0.2716968998072252, "TRIUMEQ": 2.5162463048154478, "TRULICITY": 0.5659615801007303, "TRUVADA": 7.88866961075191, "VALSARTAN": 7.221032473508703, "VAXZEVRIA": 0.0065644379261554, "VEKLURY": 1.9056659585471285, "VELTASSA": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1597.json
index 825288c069d..c74b797db54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1597.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1597.json
@@ -1 +1 @@
-{"ASPARAGINASE": 107.35954956553772, "BUSULFAN": 27.285836494781847, "KEYTRUDA": 15.649534076048342, "MITOTANE": 1979.9628794670311, "OPDIVO": 26.05312368843499, "SUTENT": 2.7399719840646366}
\ No newline at end of file
+{"SPIKEVAX": 34.88831879106123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1598.json
index 04cf38c411b..60a42cbe145 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1598.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1598.json
@@ -1 +1 @@
-{"CANCIDAS": 362.8002460586913, "CASPOFUNGIN": 574.5119028097828}
\ No newline at end of file
+{"SPIKEVAX": 11.38204589021447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1599.json
index 479d6488b63..885bab6ce54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1599.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1599.json
@@ -1 +1 @@
-{"CYTARABINE": 17.78686887311397}
\ No newline at end of file
+{"OPSUMIT": 79.29069045120157, "SPIKEVAX": 2.640373705198257, "null": 0.502161135947256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/16.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/16.json
index d2ee377e45f..8fdc65842d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/16.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/16.json
@@ -1 +1 @@
-{"CIMZIA": 5.194013025161884, "LANTUS": 4.285708092401096, "STELARA": 11.840779213632006, "null": 1.1134300690669712}
\ No newline at end of file
+{"GAZYVARO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/160.json
index 40f6a930e4d..db9fc391e70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/160.json
@@ -1 +1 @@
-{"ADVAGRAF": 15.33633069742082, "ALEMTUZUMAB": 3.17974527033292, "ALIMTA": 1.9784558776545769, "ANORO": 2.085492965630205, "APROVEL": 2.473225725195088, "ASPARAGINASE": 2.955839166215123, "ATAZANAVIR": 1.79561153794826, "AVASTIN": 1.480958851003077, "BEVACIZUMAB": 1.0273393167003666, "BORTEZOMIB": 3.196000370771182, "BUSILVEX": 14.320446438032931, "BUSULFAN": 12.648409319138288, "CANCIDAS": 5.166730857925002, "CARFILZOMIB": 4.095297045844945, "CARMUSTINE": 3.9642173008982144, "CASPOFUNGIN": 8.445803643022145, "CELLCEPT": 5.898368638864629, "CHLORHEXIDINE": 1.3740796884634237, "CICLOSPORIN": 2.629765594785154, "CUBICIN": 8.728420295067407, "CYTARABINE": 3.0476904407998053, "DEXAMETHASONE": 2.978169948242065, "DOCETAXEL": 2.416084371920168, "ENBREL": 1.0354825336612463, "ERBITUX": 5.644861881524675, "EXJADE": 1.1178023550096106, "FENTANYL": 3.383247071842733, "FILGRASTIM": 5.646135107770378, "GANCICLOVIR": 6.5106134136318365, "HUMAN": 2.9741158127953558, "HYDROCORTISONE": 2.1424906772319168, "IBUPROFEN": 2.3897424803225733, "ICLUSIG": 1.957711064729029, "INCIVO": 2.0402518939352268, "IRESSA": 3.937171148402339, "JAKAVI": 2.0858421150996, "JEVTANA": 2.651218122067656, "KALETRA": 5.862990186903089, "KEYTRUDA": 1.9435334949911385, "KYPROLIS": 8.637716010481396, "LEMTRADA": 2.14872331314692, "LEVOFLOXACIN": 2.114842279257867, "MABTHERA": 3.929758691381151, "METHOTREXATE": 2.909579435012572, "MIDAZOLAM": 4.233937740702786, "MYCOPHENOLATE": 2.926447753267604, "NEULASTA": 6.764957474492991, "NOVOSEVEN": 10.83044446029163, "NPLATE": 2.977634247453474, "OLANZAPINE": 1.4536614861856751, "PEGINTERFERON": 1.3746886126725184, "PEGINTRON": 3.177103189258625, "PRIVIGEN": 1.751821128238643, "REMDESIVIR": 27.42513871336273, "RIBAVIRIN": 1.7367321390226582, "RITUXIMAB": 2.666724896224331, "ROACTEMRA": 1.6675523667845242, "SILDENAFIL": 1.789160438945914, "SOLIRIS": 1.4331744333924883, "SUFENTANIL": 4.355654829220852, "SYNAGIS": 2.907248433349792, "TAGRISSO": 1.553166663580991, "TAMIFLU": 6.679424789011901, "THIOTEPA": 17.10351741163306, "TIGECYCLINE": 22.622277115187547, "TRACLEER": 2.070060503098204, "VEKLURY": 10.874998640123248, "VORICONAZOLE": 3.789822796196181, "null": 1.5925551492741432}
\ No newline at end of file
+{"null": 0.998193471464212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1600.json
index 48b439b43f2..2b5e5f315da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1600.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1600.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7708264773798823, "GARDASIL": 9.508103438573952}
\ No newline at end of file
+{"ASPARAGINASE": 13.16169259847029, "BUSILVEX": 103.77352728849492, "BUSULFAN": 27.812910455059, "CASPOFUNGIN": 62.59636559945123, "CICLOSPORIN": 2.652533544126967, "CYTARABINE": 20.62004837738728, "EPIVIR": 26.825761801253947, "EXJADE": 5.538900191804967, "OPSUMIT": 17.566327355683875, "SPIKEVAX": 0.2651373141267847, "TRACLEER": 19.469518111938108, "null": 1.11531956278031}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1601.json
index abd9b01b937..593f58c4baf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1601.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1601.json
@@ -1 +1 @@
-{"ABACAVIR": 1.9005268212855229, "AFINITOR": 2.4324825114246997, "ALEMTUZUMAB": 8.794277114750273, "AUBAGIO": 17.91193502284671, "AZATHIOPRINE": 3.0411762716033883, "BENZODIAZEPINES": 69.14503867357573, "BUPRENORPHINE": 2.806281438604188, "BUSULFAN": 3.715261734248279, "CICLOSPORIN": 7.94438388864027, "CYTARABINE": 2.580033639044916, "DEXAMETHASONE": 5.163146596272349, "EFAVIRENZ": 10.886206501339606, "FAMPYRA": 8.34742246284733, "GILENYA": 101.42805789536058, "IBUPROFEN": 2.3206654160323907, "KEPPRA": 1.7226741026182266, "KESIMPTA": 14.729543421403823, "LAMIVUDINE": 9.040011859027077, "LEMTRADA": 17.33789541689722, "LEVETIRACETAM": 1.9321107313852688, "LYRICA": 2.038977404706756, "MAVENCLAD": 10.44359074066859, "MEKINIST": 11.914530964391025, "METHOTREXATE": 1.7219001789222663, "PEMBROLIZUMAB": 5.045507899970961, "PLEGRIDY": 9.487092350419394, "SIMPONI": 1.1889069127698173, "SOLIRIS": 1.550168649848392}
\ No newline at end of file
+{"ARAVA": 0.1709612232942913, "BUDESONIDE": 1.9610939093363968, "BUPRENORPHINE": 4.672467996328803, "CARFILZOMIB": 13.584562119208272, "CELLCEPT": 2.657640193760594, "CLOPIDOGREL": 1.054402249578981, "COMIRNATY": 0.1334706028785808, "CYMBALTA": 0.8719704695137817, "CYTARABINE": 6.377455557356458, "DEXAMETHASONE": 3.120193142015659, "ELIQUIS": 3.0465828399501658, "EXFORGE": 2.2341301141439827, "EXJADE": 2.46488971672355, "GARDASIL": 0.5449787593898757, "HUMALOG": 1.2055474650145703, "HUMIRA": 1.6510476252982569, "IBRANCE": 3.102733683807813, "JAKAVI": 2.402887974818406, "JANUVIA": 1.6645619862810923, "LANTUS": 1.2774769001737554, "LEVOFLOXACIN": 1.2948117055989512, "LYRICA": 2.3173322770080422, "METHOTREXATE": 1.6064953521792391, "OLANZAPINE": 0.8735491845963657, "PEGASYS": 2.9058122341275303, "PEGINTERFERON": 9.098414215858968, "PEGINTRON": 7.340849029817821, "PLAVIX": 2.4482325684990345, "REVATIO": 4.327913353740692, "ROACTEMRA": 1.890599532493225, "SIMPONI": 0.8747837743619749, "SPIKEVAX": 0.0941627551016487, "SPRYCEL": 5.009976933338447, "SUTENT": 3.284443840798655, "TOZINAMERAN": 0.7047054485885577, "VAXZEVRIA": 0.1919165637445377, "VFEND": 6.716272222252268, "VIAGRA": 1.701896400419257, "XELJANZ": 1.835714321028664, "ZOSTAVAX": 3.57587911894633, "null": 1.0093877387799193}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1602.json
index ad474024b82..ee192127fe6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1602.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1602.json
@@ -1 +1 @@
-{"BLINCYTO": 669.3600734530287, "CYTARABINE": 35.37615033599663, "ICLUSIG": 159.99395438148198, "KYMRIAH": 89.18146417743372}
\ No newline at end of file
+{"null": 1.2235218531283787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1603.json
index dc56c7c35cf..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1603.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1603.json
@@ -1 +1 @@
-{"BENLYSTA": 133.52816334255775}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1604.json
index b1e31cca2bd..68d389aee7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1604.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1604.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 24.31886633760292, "CELLCEPT": 30.72718019611704, "CICLOSPORIN": 22.70045771742604, "CYTARABINE": 80.22808013371929, "DOXORUBICIN": 27.93473138313545, "EPIVIR": 38.90920211271096, "KYMRIAH": 26.42000969427001, "METHOTREXATE": 24.451601587179177, "RITUXIMAB": 22.012182381995828}
\ No newline at end of file
+{"null": 1.8339071526764503}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1605.json
index 921972faaad..ce183c42598 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1605.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1605.json
@@ -1 +1 @@
-{"METHOTREXATE": 1229.3545372773394}
\ No newline at end of file
+{"PEGASYS": 3.5058034967179688, "null": 1.474180015520841}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1606.json
index 0f31049d786..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1606.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1606.json
@@ -1 +1 @@
-{"null": 2.7985964375096817}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1607.json
index 3d768af6bf9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1607.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1607.json
@@ -1 +1 @@
-{"CELLCEPT": 8.689757655873368, "DEXAMETHASONE": 7.549605090733313, "GARDASIL": 3.7601409626398254}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1608.json
index 67569953e04..aea06151a82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1608.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1608.json
@@ -1 +1 @@
-{"AVAMYS": 15.770196113958123, "BUDESONIDE": 5.2225073673943845, "ENTYVIO": 51.167153941902775, "HYDROCORTISONE": 37.5807670380101, "null": 1.144190951876704}
\ No newline at end of file
+{"null": 0.4546645556637538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1609.json
index 22302783e2a..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1609.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1609.json
@@ -1 +1 @@
-{"CYMBALTA": 16.4747193198671, "OMALIZUMAB": 38.997590582471325}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/161.json
index 942e0f53bc4..5fa72b5b39c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/161.json
@@ -1 +1 @@
-{"ADEMPAS": 3.2624012654356576, "ALEMTUZUMAB": 1.7028277191450876, "ALIMTA": 2.7962291805598927, "AMINOSALICYLIC": 1.1049593124491337, "AVANDIA": 2.3903323532447263, "AZACITIDINE": 3.998907967458603, "BEDAQUILINE": 7.586738868796107, "BRIDION": 3.0509221317403896, "BUSULFAN": 1.7012598798486704, "BYETTA": 1.3369766805818617, "CABOMETYX": 1.547112975077915, "CANCIDAS": 4.904692316666604, "CASPOFUNGIN": 3.2844794747513832, "CELLCEPT": 1.14304509575657, "CICLOSPORIN": 1.2241832811896034, "CLOPIDOGREL": 1.13069741346783, "CUBICIN": 2.9269676779482365, "CYTARABINE": 2.396873713587975, "DEXAMETHASONE": 3.3362800928455103, "ELIQUIS": 2.088853876895668, "ESBRIET": 4.170461716051188, "EXJADE": 1.0028559099930665, "FASENRA": 3.228040037309573, "FENTANYL": 2.5682955349649728, "FILGRASTIM": 4.631085458461365, "FIRDAPSE": 5.756416375761702, "HYDROCORTISONE": 2.442643023124855, "INVOKANA": 16.90788920558382, "IRESSA": 6.8508167402690034, "IRINOTECAN": 1.7528610879706097, "JANUMET": 1.820832052839424, "JANUVIA": 1.864076750607004, "KALETRA": 1.0102324560922942, "KEYTRUDA": 1.6431087178838608, "KYMRIAH": 1.6698980274242183, "KYPROLIS": 3.782422941823484, "LAMIVUDINE": 3.186311737475385, "MEPOLIZUMAB": 1.5919010650795595, "MIDAZOLAM": 2.1240334981939646, "MYCOPHENOLATE": 1.870227713268693, "NAGLAZYME": 5.054972475146406, "NEULASTA": 1.1378809326634478, "NOXAFIL": 4.208014704671731, "NPLATE": 3.064471804300969, "NUCALA": 1.908237811146904, "OFEV": 2.695192903565324, "OLANZAPINE": 1.3931985392260342, "ONGLYZA": 7.949871630144918, "OPDIVO": 1.2112850583065895, "OPSUMIT": 6.627407599890486, "PLAVIX": 1.0391047637992117, "PRIVIGEN": 1.1691799565620358, "REMDESIVIR": 26.153673107560103, "REVATIO": 2.910069441583389, "RITUXIMAB": 1.5619476686591198, "ROACTEMRA": 2.140948477912535, "SILDENAFIL": 2.0849890719467794, "SOLIRIS": 1.3134060377998718, "SPINRAZA": 16.77516946998773, "SPRYCEL": 1.175735574679645, "SYNAGIS": 6.42624382479321, "TAGRISSO": 1.5984066759605466, "TAMIFLU": 1.5180179236661702, "TORISEL": 3.3555354295531385, "TRACLEER": 6.624762921550798, "TRELEGY": 1.6489605246959935, "VEKLURY": 6.444266261739045, "XARELTO": 3.711039483353092, "XOLAIR": 1.0122551537329263, "YESCARTA": 1.892349863683479, "ZOSTAVAX": 2.00413730896295, "null": 1.0754992607934932}
\ No newline at end of file
+{"ZOSTAVAX": 489.94630389484894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1610.json
index 631c7b1e4bc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1610.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1610.json
@@ -1 +1 @@
-{"BRAFTOVI": 22.94528027908625, "COBIMETINIB": 172.46883419062755, "COTELLIC": 78.12012832584566, "VIAGRA": 36.12022254020403, "null": 1.401832212673785}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1611.json
index 2bfb6c5db18..ff87def920f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1611.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1611.json
@@ -1 +1 @@
-{"BRILIQUE": 363.1932656504565, "BUPRENORPHINE": 14.586589716761187, "CYTARABINE": 22.8904238492737, "PRASUGREL": 484.4571737531444}
\ No newline at end of file
+{"FENTANYL": 1060.4484356138194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1612.json
index 913a9c32823..c428e1e96b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1612.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1612.json
@@ -1 +1 @@
-{"null": 2.3694819820917625}
\ No newline at end of file
+{"FENTANYL": 58.9575070863792, "null": 1.9648859654261528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1613.json
index 495b86a8515..e33609509b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1613.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1613.json
@@ -1 +1 @@
-{"ADCIRCA": 25.697394403942678, "EXJADE": 4.467796382445273, "FIRDAPSE": 34.560489657803785, "INTRONA": 23.25685931960968, "JANUMET": 6.006132464685732, "JANUVIA": 5.937037726718078, "KEYTRUDA": 5.071598737092821, "NEULASTA": 20.01993553939071, "OPSUMIT": 20.51310157002341, "RUCONEST": 167.16862441343702, "TRACLEER": 7.387664812756595, "null": 1.8941164276702105}
\ No newline at end of file
+{"ASPARAGINASE": 17.833106748120954, "COMIRNATY": 0.062548303637856, "CYTARABINE": 13.54617772855821, "DEXAMETHASONE": 5.643739498963088, "JAKAVI": 8.738616695828075, "KYMRIAH": 66.71422532841393, "ROACTEMRA": 28.468541717910824, "VAXZEVRIA": 0.5110375188988674, "null": 1.1798792645395002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1614.json
index a1fca8c37ec..8868fd666bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1614.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1614.json
@@ -1 +1 @@
-{"null": 2.4603171588385395}
\ No newline at end of file
+{"CLOPIDOGREL": 3.196805451438635, "COMIRNATY": 0.6341438581232046, "KYMRIAH": 50.14012708155608, "SPIKEVAX": 0.3591341868917351, "VAXZEVRIA": 2.150600888961913, "null": 0.6965112806628992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1615.json
index 387937aa441..2bf95180d92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1615.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1615.json
@@ -1 +1 @@
-{"null": 1.120368689581554}
\ No newline at end of file
+{"BARICITINIB": 5597.03623549758, "COMIRNATY": 0.220979510306467, "TOZINAMERAN": 0.8832877809751207, "VAXZEVRIA": 0.4472424829103537, "null": 0.7525973781500582}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1616.json
index b0ba0c6b840..97e02770a6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1616.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1616.json
@@ -1 +1 @@
-{"ALLI": 4682.721906056164, "null": 1.273587984175299}
\ No newline at end of file
+{"null": 1.4022921896664136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1617.json
index 5def7477e97..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1617.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1617.json
@@ -1 +1 @@
-{"CYMBALTA": 15.580359322997642, "null": 1.5606479191974876}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1618.json
index 076fe27e43d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1618.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1618.json
@@ -1 +1 @@
-{"GARDASIL": 3.200512348781104, "null": 2.802600716165156}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1619.json
index 7e0a301f3e8..c6490dabd28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1619.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1619.json
@@ -1 +1 @@
-{"KEPPRA": 3.1839108682102157, "OLANZAPINE": 4.422468660015504, "null": 5.39611190431455}
\ No newline at end of file
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/162.json
index eaa979f46d8..2470476a19a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/162.json
@@ -1 +1 @@
-{"GARDASIL": 5.391267294317867, "ZOSTAVAX": 38.49239943697943}
\ No newline at end of file
+{"null": 4.352060272798767}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1620.json
index de5d2fb0f45..8c0618909c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1620.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1620.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 8.903028453938528, "ELIQUIS": 17.679380060402934, "PLAVIX": 16.47518721007987, "null": 1.7542087000281903}
\ No newline at end of file
+{"null": 4.058086938025601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1621.json
index 6051788527d..d7ef1856738 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1621.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1621.json
@@ -1 +1 @@
-{"BRILIQUE": 5.5266718270642325, "CLOPIDOGREL": 14.629560660219465, "EFIENT": 38.11089996078156, "ELIQUIS": 30.256845225856573, "EVENITY": 9.53038046414173, "LIXIANA": 26.738081360684, "NEXAVAR": 4.653300268645264, "PEGASYS": 2.882877143779838, "PLAVIX": 10.645445404572689, "XARELTO": 10.04960361465968, "null": 1.3890976253155989}
\ No newline at end of file
+{"BUSULFAN": 189.9194493968507, "COMIRNATY": 0.3568893051000552, "DOXORUBICIN": 185.46856782293065, "SOMATROPIN": 128.62945455890866, "null": 1.1402032970077134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1622.json
index d0f6f23aa44..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1622.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1622.json
@@ -1 +1 @@
-{"COMBIVIR": 84.8471967157688, "null": 2.1366854047680577}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1623.json
index 77229b449f9..e796d50b3bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1623.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1623.json
@@ -1 +1 @@
-{"AIMOVIG": 3.17833712947992, "AVANDIA": 2.545929628653369, "CLOPIDOGREL": 1.861411465055083, "COMIRNATY": 1.3845993132061492, "ELIQUIS": 5.906671324338264, "EYLEA": 7.5041412208292195, "JARDIANCE": 3.143025984803554, "PEGINTRON": 4.459796079300907}
\ No newline at end of file
+{"DEXAMETHASONE": 27.04724523767948, "null": 1.6120566335216608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1624.json
index 11339d4c489..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1624.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1624.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0592395894825684}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1625.json
index ef3a34482f9..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1625.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1625.json
@@ -1 +1 @@
-{"AZILECT": 196.65092767014187, "COMIRNATY": 1.855160206049727, "SPIKEVAX": 1.3136716106589612, "TOZINAMERAN": 2.072595285767506, "VAXZEVRIA": 1.2529025913835514}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1626.json
index a9960df1428..415321de570 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1626.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1626.json
@@ -1 +1 @@
-{"EMTRICITABINE": 23.98158578382504, "KALETRA": 8.909395589077814, "KEPPRA": 3.1606613623561204, "null": 2.525140640427933}
\ No newline at end of file
+{"VAXZEVRIA": 2.6585798010698283, "null": 0.3160613933984168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1627.json
index 7cd5cb1320c..0dd21ed9463 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1627.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1627.json
@@ -1 +1 @@
-{"ELIQUIS": 6.849158639178266, "null": 1.4096050487996352}
\ No newline at end of file
+{"ABASAGLAR": 67.53836703459412, "ACTRAPID": 7.130757524787525, "ADENURIC": 4.061746726844235, "AFINITOR": 1.1512357032280047, "ALPELISIB": 9.06533303656946, "APIDRA": 31.088032140875683, "ARANESP": 0.4663966058224036, "ARAVA": 0.1039286841725181, "ARIPIPRAZOLE": 1.3340011959793383, "AVAMYS": 0.6614601128617742, "BUPRENORPHINE": 0.8650422286005248, "BYDUREON": 4.652338023207815, "BYETTA": 4.729786886055354, "CHAMPIX": 0.5722052461689674, "COMIRNATY": 0.066996288954963, "CYMBALTA": 0.2475345690014888, "DULAGLUTIDE": 19.629489300989093, "ELIQUIS": 0.3411276466470427, "EMPAGLIFLOZIN": 4.100697428310465, "ENTRESTO": 0.7705107229803906, "EUCREAS": 4.7680095273092045, "FIASP": 48.14319129116627, "FORSTEO": 0.3095925587311631, "FORXIGA": 4.3956258523771385, "GALVUS": 4.3753127507365885, "GARDASIL": 0.4240508500545422, "GLUCAGON": 6.807152851030573, "HUMALOG": 41.51675897751431, "IBRANCE": 0.3582210521773, "INSULATARD": 19.79542384290868, "INSULIN": 21.82052023336469, "INSUMAN": 32.15073150275138, "ISOPHANE": 20.3566449972741, "JANUMET": 12.311500053147006, "JANUVIA": 7.728435781967854, "JARDIANCE": 7.686907579985408, "KEYTRUDA": 0.7407700991421466, "LANTUS": 21.267013869898182, "LEVEMIR": 15.896469709231988, "LIPROLOG": 53.4575286452238, "LYRICA": 0.5807967828792887, "LYUMJEV": 35.67015555704494, "MIXTARD": 21.036016878035117, "NOVORAPID": 39.74554720338875, "OLANZAPINE": 0.3743530754882412, "OMALIZUMAB": 0.7698350577319254, "OZEMPIC": 10.32264089727398, "PEGASYS": 0.1865416798016796, "SPIKEVAX": 0.0458038568618467, "STELARA": 0.2126322290709321, "SUTENT": 0.7148537806196162, "TOUJEO": 31.597072799389988, "TOZINAMERAN": 0.1797761977283112, "TRESIBA": 24.776360047796075, "TRULICITY": 10.467575420659744, "VAXZEVRIA": 0.060811298637011, "VICTOZA": 4.417518330553008, "XELJANZ": 0.2846405338210735, "ZOSTAVAX": 0.9357726559281432, "ZYPREXA": 0.6481087287528833, "null": 0.4944770595481378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1628.json
index 0591d57d6e0..d9d67466702 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1628.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1628.json
@@ -1 +1 @@
-{"KEPPRA": 148.22088956427817}
\ No newline at end of file
+{"ABASAGLAR": 19.4507735038502, "ABILIFY": 0.3777400732407897, "ACTOS": 9.871303501438664, "ACTRAPHANE": 13.51894874585776, "ACTRAPID": 8.137205291976633, "AFINITOR": 0.9766666845575186, "ANAKINRA": 0.7532023257356248, "APIDRA": 23.33990383947555, "AVANDIA": 1.150762414993023, "BAQSIMI": 49.68690995851325, "BUPIVACAINE": 0.662409825262201, "BYDUREON": 5.714117038877999, "BYETTA": 10.095433237694916, "CABOMETYX": 0.3960565902054167, "CELLCEPT": 0.2783843914170211, "CHAMPIX": 0.3484794159848851, "CICLOSPORIN": 0.1551996655152706, "COMIRNATY": 0.0531382005202634, "COSENTYX": 0.1303282500095013, "CYMBALTA": 0.5341983292345208, "DULAGLUTIDE": 30.379715554242512, "ELIQUIS": 0.2221955084847072, "ENTRESTO": 1.0883821525915378, "ESBRIET": 0.367992804838864, "EVISTA": 0.5831441253466211, "EXFORGE": 0.7063044584649177, "EXJADE": 0.3494335947158521, "FIASP": 18.596151662033535, "FORXIGA": 2.130332108857288, "GALVUS": 2.4107447343819155, "GARDASIL": 0.1828304074753084, "GLIBENCLAMIDE": 6.087563785479241, "GLUCAGON": 48.71665973824195, "HUMALOG": 61.93450262721566, "IBRANCE": 0.4793940965745824, "INLYTA": 0.4055205921099601, "INSULATARD": 12.703666656704058, "INSULIN": 21.98942813457114, "INSUMAN": 11.79215330665054, "INVOKANA": 4.678144224379471, "JANUMET": 3.414639783845977, "JANUVIA": 3.6641696805155335, "JARDIANCE": 2.3706431022853023, "KAFTRIO": 0.6554211478575386, "KEPPRA": 0.2355339548350614, "KEYTRUDA": 0.0772413222623521, "LANTUS": 32.56041126892916, "LEVEMIR": 29.185889943422477, "LEVOFLOXACIN": 0.1345832578948802, "LYRICA": 0.2505705594612895, "LYUMJEV": 12.020110699608816, "MICARDIS": 0.8443059182446674, "MIXTARD": 7.097214063538854, "NEXAVAR": 0.2624132259925864, "NOVONORM": 2.889050155628556, "NOVORAPID": 13.57905534041813, "OLANZAPINE": 0.1457912616876395, "OMALIZUMAB": 0.3926244931616293, "ONGLYZA": 3.954800841711125, "OPSUMIT": 0.636402690262565, "OZEMPIC": 9.538690544824007, "PEGASYS": 0.7918837165195197, "PEGINTERFERON": 0.4115212543457287, "PEGINTRON": 0.1564719186205287, "PLAVIX": 0.2666245122766214, "REPAGLINIDE": 5.147961219419824, "RYBELSUS": 2.5518762333705185, "SAXENDA": 1.5394577208122853, "SPIKEVAX": 0.0369730346671057, "SPINRAZA": 1.1347292441570336, "STELARA": 0.1038811934620218, "SUBOXONE": 0.3193156918164882, "SUTENT": 1.473791759769031, "TOUJEO": 27.680425353446108, "TOZINAMERAN": 0.213162324339186, "TRACLEER": 0.2727111351097869, "TRESIBA": 21.921608310250704, "TRULICITY": 7.216397246987838, "VAXZEVRIA": 0.0454796581719994, "VELTASSA": 2.6863316790540908, "VFEND": 0.5508858407039644, "VIAGRA": 0.3769678063601829, "VICTOZA": 6.525500249064569, "VOTRIENT": 0.3788102392513561, "XELJANZ": 0.2185126073575805, "XOLAIR": 0.2999478968876367, "XTANDI": 0.6200861642323444, "XYREM": 0.9570822330703392, "ZYPREXA": 0.459683664640168, "null": 0.652170320331935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1629.json
index 4a83d03b98c..aec88566466 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1629.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1629.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 5.47832433615844, "ELIQUIS": 20.343399673502446}
\ No newline at end of file
+{"null": 7.402773206193315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/163.json
index 7584baad222..d9e108d4f86 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/163.json
@@ -1 +1 @@
-{"COMIRNATY": 3.9481615494290017, "EFAVIRENZ": 49.32426849592806, "PEGASYS": 2.969714753494276}
\ No newline at end of file
+{"FORXIGA": 350.7704538900232, "JARDIANCE": 70.53199874589743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1630.json
index bbbb13b088e..51027418960 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1630.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1630.json
@@ -1 +1 @@
-{"ELIQUIS": 3.0181532396157995, "TASIGNA": 11.71336612691688}
\ No newline at end of file
+{"ABASAGLAR": 29.97973339863641, "ACTOS": 4.7917306369997466, "ACTRAPID": 35.44021146286171, "AFINITOR": 0.4657960752360068, "ANAKINRA": 2.094585372212004, "APIDRA": 35.04649213141235, "AVANDIA": 0.6732616419058778, "BYDUREON": 5.38511391259352, "BYETTA": 6.160157910798752, "CAPECITABINE": 1.105160035654448, "CHAMPIX": 0.7261639722453642, "CLOPIDOGREL": 0.3856493017792914, "COAPROVEL": 2.140918855768028, "COMIRNATY": 0.0990234395984009, "ELIQUIS": 0.1730250654370575, "EMPAGLIFLOZIN": 3.053651763666667, "ENTRESTO": 0.575035203061232, "FIASP": 67.70944219940554, "FORXIGA": 6.28788861034112, "GALVUS": 7.824770180694904, "HUMALOG": 30.05435965750833, "INSULATARD": 10.586122428393352, "INSULIN": 39.67818794273048, "INSUMAN": 44.4145866971573, "JANUMET": 5.736486694530003, "JANUVIA": 3.8786111760741258, "JARDIANCE": 1.1948866948408918, "LANTUS": 33.10135155632118, "LEVEMIR": 49.33876671083628, "LIPROLOG": 41.27105490551752, "LYRICA": 0.7715020351378944, "LYUMJEV": 29.7734680108193, "MEPOLIZUMAB": 0.6842967587142385, "MIXTARD": 19.7366608186142, "NOVORAPID": 56.56897214049346, "ONGLYZA": 5.801736209922603, "PEGASYS": 0.2806590496865333, "SPIKEVAX": 0.0762951585180149, "SUTENT": 0.4348213393402066, "TOUJEO": 36.943233230655885, "TOZINAMERAN": 0.1189586838871332, "TRESIBA": 25.668338153576983, "TRULICITY": 2.718203392811243, "VAXZEVRIA": 0.1112780340327826, "VICTOZA": 3.3876181909661365, "ZYPREXA": 0.3092672782452449, "null": 0.4345198260061608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1631.json
index 25ea90d4e70..c9585ab701d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1631.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1631.json
@@ -1 +1 @@
-{"ICLUSIG": 60.35980947481789, "TASIGNA": 77.25596773348751}
\ No newline at end of file
+{"ABASAGLAR": 36.43872731950109, "ABILIFY": 2.7654011047652136, "ACTOS": 6.529147835667302, "ACTRAPHANE": 26.998733641471016, "ACTRAPID": 18.67705150122187, "AFINITOR": 1.77088210711468, "AIMOVIG": 0.098472509387935, "ALIMTA": 0.1910365243701655, "ALPELISIB": 5.336804459230629, "AMINOSALICYLIC": 0.1609597904511316, "ANAKINRA": 0.3459349357831377, "ANORO": 0.201522783289912, "ANTIBIOTICS": 1.0075447137526314, "APIDRA": 22.67842091984605, "APIXABAN": 2.2999268701651547, "APROVEL": 0.6632045154372221, "ARANESP": 0.1009492829717448, "ARAVA": 0.0982817026819293, "ARIPIPRAZOLE": 0.5437040383496409, "ASPARAGINASE": 0.1004071092736499, "ATRIPLA": 0.015435226304845, "AUBAGIO": 0.2313362153308467, "AVAMYS": 0.1185195716782093, "AVANDAMET": 0.3124225060453434, "AVANDIA": 0.5696356454077208, "AVASTIN": 0.1015291305035532, "BAQSIMI": 7.972321510755766, "BENLYSTA": 0.1202288100943105, "BETMIGA": 0.4581899856881752, "BIKTARVY": 0.5652573098438158, "BOSULIF": 0.3293772124474072, "BRAFTOVI": 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"ZOSTAVAX": 0.2730764897289911, "ZYPADHERA": 0.5912581853720928, "ZYPREXA": 2.584120456938054, "null": 0.6135607651589184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1632.json
index 18953f05350..c3fd32d5d83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1632.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1632.json
@@ -1 +1 @@
-{"CELECOXIB": 40.87677108402424, "COVID19": 1.5272130523854066, "ESOMEPRAZOLE": 139.14963079593562, "NOVOSEVEN": 76.9067716569572, "VAXZEVRIA": 1.9756985468449124}
\ No newline at end of file
+{"GARDASIL": 46.021967412803335, "JARDIANCE": 34.79587899335255, "SPIKEVAX": 8.488734274519185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1633.json
index d5a9ff841e5..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1633.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1633.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 86.48771128702572, "CASPOFUNGIN": 235.96961035641752, "IBRUTINIB": 287.7403297789392, "RITUXIMAB": 25.21120750732176}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1634.json
index 128bbf04922..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1634.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1634.json
@@ -1 +1 @@
-{"null": 1.6317463676500423}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1635.json
index 9fb774b63e0..0c595cd4131 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1635.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1635.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 4.414156399113344, "CICLOSPORIN": 2.428905173785714, "JAKAVI": 2.94734330389285, "KEPPRA": 1.9287643743544087, "LEVETIRACETAM": 4.044566570875708, "MIDAZOLAM": 25.500959837984773, "OLANZAPINE": 3.8895803964417466, "PLAVIX": 1.1912684443931998, "ZOSTAVAX": 3.4912753068742, "ZYPREXA": 2.798446420336941, "null": 2.077087126163156}
\ No newline at end of file
+{"null": 4.419712356056523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1636.json
index 6155c3a27b1..a67802ee27c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1636.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1636.json
@@ -1 +1 @@
-{"null": 1.9014649402371044}
\ No newline at end of file
+{"ASPARAGINASE": 111.96591464873758, "null": 2.109518532319228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1637.json
index 016c4394b16..c00a7e9d3ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1637.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1637.json
@@ -1 +1 @@
-{"null": 1.289217892627409}
\ No newline at end of file
+{"SOMAVERT": 1567.6136640463608, "null": 4.251217245915139}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1638.json
index b11e0d68ae1..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1638.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1638.json
@@ -1 +1 @@
-{"ASPARAGINASE": 478.4146558212937}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1639.json
index 3f536682659..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1639.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1639.json
@@ -1 +1 @@
-{"GARDASIL": 46.8022731247579}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/164.json
index 3057f7ab06c..2f39cb911b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/164.json
@@ -1 +1 @@
-{"COMIRNATY": 6.211514709348975}
\ No newline at end of file
+{"null": 6.2933611778800325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1640.json
index 2f8e609f90d..b31830e9533 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1640.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1640.json
@@ -1 +1 @@
-{"null": 1.138934235471603}
\ No newline at end of file
+{"COMIRNATY": 0.3364131177198908, "null": 0.8902201138745662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1641.json
index 7f539defb46..e6e67aee351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1641.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1641.json
@@ -1 +1 @@
-{"null": 1.760684130622174}
\ No newline at end of file
+{"null": 1.5228310199198265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1642.json
index 4b61e377513..5f45c682649 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1642.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1642.json
@@ -1 +1 @@
-{"AIMOVIG": 1.0893485589396734, "ARIPIPRAZOLE": 1.6240505719679648, "AUBAGIO": 2.4298664088616526, "BENLYSTA": 1.965578426226056, "CYMBALTA": 1.333643011416601, "ELIQUIS": 1.7542546718714598, "EXFORGE": 2.0859001851400167, "HUMALOG": 3.457213742481981, "HYDROCORTISONE": 17.567016299061585, "IBRANCE": 2.451450997669994, "IBUPROFEN": 1.6308850501471597, "INSULIN": 1.7068236866600708, "IRESSA": 3.181319889664957, "KEPPRA": 2.034030680940458, "LANTUS": 1.87070034144676, "LEVETIRACETAM": 2.050262731303567, "LYRICA": 2.760922985114899, "MEKINIST": 2.381488841366805, "RITUXIMAB": 3.164397343980253, "SUBOXONE": 3.3886342689814013, "TOVIAZ": 3.632783778645541, "VIAGRA": 1.5889790751416917, "XELJANZ": 1.1697780096063315, "XTANDI": 1.2318879903808846, "ZYPREXA": 1.2716933701779871, "null": 1.6136374087069318}
\ No newline at end of file
+{"ARAVA": 2.179534045151754, "CYTARABINE": 22.53023608901824, "null": 0.8293634930267374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1643.json
index 8ec153407f8..b28dece4c99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1643.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1643.json
@@ -1 +1 @@
-{"null": 1.3092049495297184}
\ No newline at end of file
+{"ANAKINRA": 65.48393527440008, "COMIRNATY": 0.1700498173688546, "null": 1.062103668300365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1644.json
index 114f127e7bc..0cf207b395c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1644.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1644.json
@@ -1 +1 @@
-{"BRILIQUE": 28.692130836523496, "CLOPIDOGREL": 15.9748591714302, "EFIENT": 17.185782528429502, "ELIQUIS": 27.025039422845364, "ENOXAPARIN": 4.801119144617787, "ENTRESTO": 1.7486777803292026, "METALYSE": 393.1247726909989, "PLAVIX": 26.294385903518837, "PRADAXA": 11.21386438796598, "RASBURICASE": 73.30766422279504, "XARELTO": 13.490481591423986, "null": 1.446062525063009}
\ No newline at end of file
+{"XOLAIR": 110.40345288820612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1645.json
index 77f0055beb6..ad556c72b8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1645.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1645.json
@@ -1 +1 @@
-{"ADENURIC": 2.6200366421881203, "ADVATE": 3.8508492116380815, "ANGIOX": 6.251988302359264, "ARIXTRA": 11.069180822578817, "ASPARAGINASE": 2.0193093812864915, "AVASTIN": 2.296034218601947, "BRILIQUE": 16.28005971916398, "CASPOFUNGIN": 1.276613298520639, "CLOPIDOGREL": 8.637510762302227, "COTELLIC": 1.4729348466546293, "DEFITELIO": 8.521165245272234, "DUOPLAVIN": 12.375280399412684, "EBIXA": 1.9635638740238488, "EFIENT": 26.87872470910498, "ELIQUIS": 24.782486016188862, "ENOXAPARIN": 4.569085711423468, "ENTACAPONE": 1.8437982685668184, "EVENITY": 6.3443704720361405, "EXVIERA": 1.019380371255154, "EYLEA": 1.8142091127866933, "HARVONI": 1.78629452278988, "HEMLIBRA": 3.915056627534883, "ICLUSIG": 1.1833397153326697, "INLYTA": 1.3918148673340718, "INTEGRILIN": 13.394588598119425, "INTRONA": 4.178954828261928, "INVEGA": 1.940412847154828, "ISCOVER": 8.576455355686022, "JAKAVI": 1.5054316192752413, "JEVTANA": 1.4215255566165346, "LENVIMA": 5.19294244221353, "LIXIANA": 18.79735478375084, "MEKINIST": 1.7926253160259151, "METALYSE": 179.7815841222343, "MICARDIS": 1.4918481795677618, "MIDAZOLAM": 2.120634154303149, "MIRCERA": 2.6203625704273983, "NEXAVAR": 3.202158516878405, "NOVOSEVEN": 4.722719853344857, "NPLATE": 1.666314702210883, "ONCASPAR": 1.9260166100979408, "PEGASYS": 1.618963900369902, "PEGINTRON": 2.540970976298055, "PLAVIX": 22.115280497227296, "PRADAXA": 6.267278424431333, "PRASUGREL": 12.274174471349715, "PRAXBIND": 26.30702910336432, "RAPILYSIN": 325.604758280221, "REBETOL": 1.702126312763056, "RETEPLASE": 37.31248016267699, "RIVAROXABAN": 2.6629144268565463, "SILDENAFIL": 1.9552262312252024, "SOLIRIS": 1.0100784659687467, "SOVALDI": 2.4261612946622457, "SPRYCEL": 1.232177022162964, "STIVARGA": 1.2616795997473933, "SUTENT": 1.775073248706034, "TEMODAL": 3.040842909308634, "TICAGRELOR": 7.171756197195853, "TORISEL": 2.760483759069148, "VIAGRA": 1.7375334178713548, "VOTRIENT": 1.7058954177071235, "XARELTO": 10.43877444302644, "XOFIGO": 1.2672602087089957, "YERVOY": 1.4139183446337331, "null": 1.2773963484113255}
\ No newline at end of file
+{"XOLAIR": 73.89204220973382, "null": 0.9664295442984754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1646.json
index d53faa9d397..023e3f732ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1646.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1646.json
@@ -1 +1 @@
-{"MIDAZOLAM": 226.19706200438043, "null": 1.9407976366233173}
\ No newline at end of file
+{"APIDRA": 2.7055591818698197, "AVAMYS": 20.237408652798564, "BUDESONIDE": 58.37412390584598, "CICLOSPORIN": 1.9425385162623947, "CLOPIDOGREL": 1.920050087352812, "COMIRNATY": 0.2357238533186641, "FASENRA": 8.677002067949266, "GLYCOPYRRONIUM": 49.41222420313562, "HUMALOG": 0.959822877000657, "INSULIN": 3.915670379105677, "IRBESARTAN": 14.168890113224784, "MEPOLIZUMAB": 19.523328628624604, "METHOTREXATE": 12.225527173885816, "NUCALA": 4.541901384565106, "OMALIZUMAB": 30.1501693096447, "XOLAIR": 51.41391733544492, "null": 0.7381479904146185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1647.json
index 92463a317c9..9977cee8e6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1647.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1647.json
@@ -1 +1 @@
-{"null": 2.5913256838914767}
\ No newline at end of file
+{"null": 0.800415278061176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1648.json
index 9325e48e822..b544596db4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1648.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1648.json
@@ -1 +1 @@
-{"AZILECT": 238.31788633870607, "CARBIDOPA": 323.7115246479943, "null": 1.949534757279751}
\ No newline at end of file
+{"CELLCEPT": 7.935563833532542, "CICLOSPORIN": 9.807033439224488, "COMIRNATY": 0.0875505879490012, "CYTARABINE": 6.98489893239978, "HIZENTRA": 36.23493939766714, "HUMAN": 42.01471670088924, "KESIMPTA": 47.53312550050819, "SOLIRIS": 10.976265228361523, "XOLAIR": 4.002424426005726, "null": 0.69207559509448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1649.json
index c9a19d28ccc..333d3af69ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1649.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1649.json
@@ -1 +1 @@
-{"ACTOS": 1.9742011041542145, "ALIMTA": 2.3467513619486966, "ASPARAGINASE": 1.4852865006154576, "AVANDAMET": 2.357329880691526, "AVANDIA": 2.830299260737553, "AVASTIN": 3.999783308337639, "CABOMETYX": 1.0646972602744826, "CANNABIDIOL": 5.447597248538198, "CELLCEPT": 1.0835790643476504, "CLOPIDOGREL": 3.183037869673301, "COAPROVEL": 1.3311497707629547, "COMIRNATY": 1.0497531958583133, "COMTAN": 1.4928790720441532, "EFIENT": 10.28740006696944, "ELIQUIS": 13.78564970797908, "ENZALUTAMIDE": 1.9917982478150151, "ERLEADA": 1.170042930850154, "EVENITY": 37.763819754613, "EVISTA": 7.776129770855238, "EXFORGE": 1.0058652379964557, "EYLEA": 20.016398461059826, "FESOTERODINE": 51.30963731475755, "FORXIGA": 5.8897648948622265, "HEMLIBRA": 4.473312702598258, "HUMALOG": 1.6599274500714865, "HUMAN": 1.1572353601702756, "ICLUSIG": 10.697099509547677, "INFLIXIMAB": 1.3955825976849394, "INLYTA": 2.7667693661497403, "INTRONA": 2.615170887647368, "IRESSA": 4.390647290760168, "ISENTRESS": 1.231184016604298, "JAKAVI": 1.0434997491754732, "JANUVIA": 1.443849685835669, "JARDIANCE": 2.257530093549448, "JEVTANA": 1.065417971846347, "KEYTRUDA": 2.0160098101912625, "LENVIMA": 6.638697528789071, "LIXIANA": 6.839039001373485, "METFORMIN": 3.3476222809366543, "MICARDIS": 2.075308215495137, "MIRCERA": 1.702517169280925, "NEXAVAR": 3.449978452833957, "NILOTINIB": 3.666792595541985, "NOT": 1.5119475631449406, "NOVOSEVEN": 24.097896312405474, "OFEV": 1.9296996083028397, "ONCASPAR": 3.2536025978735297, "OPDIVO": 1.3743338222991035, "PEGINTRON": 2.8655319410860622, "PLAVIX": 3.1488466332521177, "PRADAXA": 2.0183107372755544, "PRAXBIND": 9.949272502517452, "RASILEZ": 1.2975056892440555, "REBETOL": 1.727059219782045, "REMICADE": 1.0307861795020208, "ROACTEMRA": 1.1366990952688238, "SAMSCA": 24.206126142812487, "SILDENAFIL": 1.2550347482675774, "SOMATROPIN": 3.2111979663106425, "SOVALDI": 3.809744463535769, "STELARA": 1.0069320169587386, "STIVARGA": 1.8543475575297044, "TAGRISSO": 3.4034875300558856, "TASIGNA": 8.42071961479401, "TEMODAL": 1.667088716349009, "VECTIBIX": 2.0934559341406835, "VEMLIDY": 7.658873699605869, "VIAGRA": 2.6578668777137664, "XARELTO": 2.1204028019335257, "XTANDI": 1.7403751205035147}
\ No newline at end of file
+{"ADCIRCA": 54.19663242197809, "ARAVA": 0.7466558684179004, "CICLOSPORIN": 3.197466410861463, "COMIRNATY": 0.2219981432363361, "DEXAMETHASONE": 5.404743698624089, "null": 1.2159824844027634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/165.json
index 1d0fdac4368..6123db8b86a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/165.json
@@ -1 +1 @@
-{"null": 3.524007618038884}
\ No newline at end of file
+{"null": 0.7237271814845543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1650.json
index 92b183ceb68..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1650.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1650.json
@@ -1 +1 @@
-{"APIXABAN": 1.281701751277835, "ASPARAGINASE": 7.932030498237815, "AVANDIA": 1.583329609145549, "AVASTIN": 3.78920540299282, "CELLCEPT": 2.92151928464957, "CICLOSPORIN": 1.3989695745174575, "CLOPIDOGREL": 1.1576208096751877, "ELIQUIS": 3.2106964201826576, "ICLUSIG": 11.802743506450035, "INSULIN": 2.0049403640211523, "LIXIANA": 9.805514585996791, "METHOTREXATE": 1.2549457908607518, "NOVOSEVEN": 49.06690376038344, "NUCALA": 1.6634882918990368, "OLANZAPINE": 2.0264991344839265, "PLAVIX": 1.0421075257993615, "SOLIRIS": 2.4499518259595185, "SUTENT": 1.0432347590676612, "ZYPREXA": 1.037073219266379, "null": 1.1907288900664328}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1651.json
index 02d9932daa1..d355ec5602b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1651.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1651.json
@@ -1 +1 @@
-{"BRILIQUE": 22.45867772055913, "CLOPIDOGREL": 12.72186839647132, "ELIQUIS": 10.679118677352198, "PLAVIX": 5.778248954039571}
\ No newline at end of file
+{"COMIRNATY": 0.1926487241331676, "KESIMPTA": 222.44735195869603, "MEPOLIZUMAB": 66.55115972222717, "null": 0.547536083405196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1652.json
index 835d2b9cb41..027688ce5dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1652.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1652.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 12.5934869229776, "ELIQUIS": 7.738648184013976}
\ No newline at end of file
+{"ARAVA": 2.2861795506924336, "null": 0.9423679503151088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1653.json
index bdfdff0de79..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1653.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1653.json
@@ -1 +1 @@
-{"ENOXAPARIN": 25.12070892307524, "SYNAGIS": 32.6368993802519, "null": 3.2265559738765006}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1654.json
index 26dbec3b5c8..b9245b6ca42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1654.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1654.json
@@ -1 +1 @@
-{"INSULIN": 329.25075376844046}
\ No newline at end of file
+{"AVAMYS": 94.81407601380678, "null": 0.4140489676554496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1655.json
index b21290d7db5..d216667b94d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1655.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1655.json
@@ -1 +1 @@
-{"ELIQUIS": 2.846693043746406, "SPIKEVAX": 1.2142264488385148, "ZOSTAVAX": 67.47869830337089}
\ No newline at end of file
+{"JARDIANCE": 30.405830531955708, "null": 0.7003312934226212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1656.json
index 6feab0c8ded..2ab4b1b1093 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1656.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1656.json
@@ -1 +1 @@
-{"APIXABAN": 3.715959814813084, "ASPARAGINASE": 10.171756413196482, "COMIRNATY": 1.1643367027868188, "COVID19": 1.1924754308274397, "ELIQUIS": 3.254039370289824, "HUMALOG": 1.5788917397684066, "NOVOSEVEN": 21.579610112702134, "ONCASPAR": 21.4923986331292, "SOLIRIS": 2.8560551110615293, "TOZINAMERAN": 2.5051525685060083, "VAXZEVRIA": 2.8302999226450063, "XARELTO": 8.356462959123247}
\ No newline at end of file
+{"ARIPIPRAZOLE": 20.417740324734883, "HUMALOG": 23.709434749887613, "INSULIN": 47.95494624043382, "LANTUS": 5.649544679426209, "null": 0.7507006187147846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1657.json
index e04ecfd8c4e..67471ad5ea8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1657.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1657.json
@@ -1 +1 @@
-{"ABACAVIR": 15.375319019851752, "BIKTARVY": 30.995252689560772, "BUSULFAN": 70.89546080389519, "CAELYX": 51.55851123437852, "CARFILZOMIB": 346.38354887758703, "CELLCEPT": 10.307633460347231, "CICLOSPORIN": 11.568456559269825, "EPIVIR": 90.456990882979, "KALETRA": 23.632172651830643}
\ No newline at end of file
+{"VAXZEVRIA": 8.704212597092177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1658.json
index 3a0e088e9ec..3e97ad1becd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1658.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1658.json
@@ -1 +1 @@
-{"DASATINIB": 170.97816419314975, "null": 2.2614637581272605}
\ No newline at end of file
+{"ADALIMUMAB": 2.479381639879818, "ARAVA": 127.69870074374388, "CYMBALTA": 1.4744359596556311, "null": 0.1429782368721937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1659.json
index 0afcf52628c..f2befda7f2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1659.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1659.json
@@ -1 +1 @@
-{"ASPARAGINASE": 13.79892204589274, "COMIRNATY": 1.8989086330033, "COVID19": 3.9754885833761295, "HUMIRA": 2.3589205436024123, "METHOTREXATE": 1.339403164725805, "NOVOSEVEN": 11.29863909780962, "ONCASPAR": 24.661065207642363, "SPIKEVAX": 1.011198924346574, "TOZINAMERAN": 1.6251254149944825, "VAXZEVRIA": 7.739945463712981}
\ No newline at end of file
+{"AFINITOR": 1.86488298676646, "APIXABAN": 1.3184863941028613, "APTIVUS": 123.41799091410346, "ARANESP": 1.6123314890010862, "ARAVA": 0.6713095329551767, "CAPECITABINE": 2.846506353598159, "CELLCEPT": 4.28839614809251, "CIMZIA": 0.8175061888390346, "CLOPIDOGREL": 3.9734008194129817, "COMIRNATY": 0.3021621848993929, "COSENTYX": 0.9333897606692874, "CYMBALTA": 0.5461611929146014, "ELIQUIS": 3.2866996062319744, "EMPAGLIFLOZIN": 10.72022974252701, "ENTRESTO": 3.172002068758169, "ENTYVIO": 4.056193899914514, "FAMPYRA": 4.116620592037755, "FORSTEO": 1.2118858453789088, "GARDASIL": 1.7802021366562537, "HUMALOG": 0.6814546861553319, "HUMIRA": 2.1214977221277405, "IBRANCE": 3.56309898436274, "IRON": 15.52186621107935, "JAKAVI": 1.7875711718433576, "LANTUS": 0.788998154182801, "METHOTREXATE": 4.237480487156184, "MICARDIS": 5.280923600748479, "OMALIZUMAB": 18.138459013915227, "OPSUMIT": 6.605909893713177, "OZEMPIC": 44.69208175911565, "PEGASYS": 1.2925396601917247, "PEGINTRON": 1.2234472240698533, "PLAVIX": 2.209327847092413, "REVATIO": 3.646606378037705, "RINVOQ": 3.851378730247112, "SEMAGLUTIDE": 53.70211449605184, "SIMPONI": 1.6245768016359017, "SOLIRIS": 1.36344072253802, "SPIKEVAX": 0.106237752837437, "STELARA": 1.1990017192944722, "SUTENT": 1.1714064912037987, "TOZINAMERAN": 0.9509645720681636, "TRACLEER": 2.378110733013505, "VAXZEVRIA": 0.2123784244514145, "XELJANZ": 3.395330508445022, "ZOSTAVAX": 0.739425248911397, "null": 0.7685947007449504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/166.json
index 4076af77b33..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/166.json
@@ -1 +1 @@
-{"null": 8.553946467711636}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1660.json
index a9b8b3d06bb..b0bc6b92a48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1660.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1660.json
@@ -1 +1 @@
-{"ASPARAGINASE": 68.8207715845906, "COMIRNATY": 1.2641436868530225, "COVID19": 1.7423932635867656, "CYTARABINE": 3.742591659437725, "ENOXAPARIN": 10.76097528749592, "ONCASPAR": 33.36910797971484, "VAXZEVRIA": 3.711956903363014}
\ No newline at end of file
+{"COMIRNATY": 0.2428259027832927, "EXJADE": 119.8258186310886, "OZEMPIC": 177.04934095640448, "PEGASYS": 3.686231978703912, "SOLIRIS": 10.418399079275746, "null": 0.9830066942073457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1661.json
index 40b3a19ab5e..49043946b46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1661.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1661.json
@@ -1 +1 @@
-{"DARUNAVIR": 85.94795592095674, "null": 2.7804684864385405}
\ No newline at end of file
+{"HUMALOG": 27.730980433168995, "JARDIANCE": 50.44918500566067, "LANTUS": 15.973194088214909, "LEVEMIR": 49.51578186783756, "NOVORAPID": 102.01209985285946, "VAXZEVRIA": 0.2380580022912764, "null": 0.1437369276979472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1662.json
index 0a6df420bf4..7a8f542ebc8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1662.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1662.json
@@ -1 +1 @@
-{"ELIQUIS": 60.58876673469882}
\ No newline at end of file
+{"FORXIGA": 58.83999369638104, "HUMALOG": 16.00010493184288, "JARDIANCE": 109.42524896861867, "LANTUS": 5.025465257723556, "LEVEMIR": 12.434047046898565, "METFORMIN": 45.93996937265378, "NOVORAPID": 89.65719519899147, "null": 0.1375633388559946}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1663.json
index 9a116254cdb..a7d24334604 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1663.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1663.json
@@ -1 +1 @@
-{"AIMOVIG": 4.103051420283254, "BENLYSTA": 8.395179214702706, "BUPIVACAINE": 28.234465703890127, "CYMBALTA": 1.6425162394798851, "FENTANYL": 5.50975895025987, "KEPPRA": 3.182914556276959, "LINACLOTIDE": 1023.2319110132846, "SPINRAZA": 177.95860879228582, "null": 1.2885236165537723}
\ No newline at end of file
+{"FORXIGA": 11.90001827425242, "HUMALOG": 3.643609260462625, "JARDIANCE": 29.149800052582247, "LEVEMIR": 33.400963248473296, "NOVORAPID": 1136.9454779448106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1664.json
index be0828d771e..d7a298122da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1664.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1664.json
@@ -1 +1 @@
-{"ACLIDINIUM": 1.0352157138044509, "ACTOS": 1.3649843274074902, "AIMOVIG": 1.2431801305815118, "ALISKIREN": 10.399097763414634, "ANGIOX": 1.8589895866383432, "APIDRA": 1.8547320750995075, "APROVEL": 1.3778779197995956, "ARANESP": 1.020223761016669, "AVANDAMET": 22.683160374407223, "AVANDIA": 24.03347993126246, "AZILECT": 1.2639724950258384, "BC": 8.078429702206204, "BOSULIF": 1.9513440481855773, "BOSUTINIB": 2.5300470520843943, "BRILIQUE": 1.0242224618622864, "BYDUREON": 1.482484702539175, "BYETTA": 1.1238274688353904, "CIALIS": 1.0723563251309347, "CLOPIDOGREL": 1.516535097250276, "COLESEVELAM": 77.26568312142449, "DABIGATRAN": 3.64274916671208, "DASATINIB": 2.220313248491585, "DESCOVY": 1.1792129099814612, "DULAGLUTIDE": 2.6034540028882702, "ELIQUIS": 10.303969557837297, "ENTRESTO": 1.3428633526850826, "ENZALUTAMIDE": 1.602942495529094, "ERLEADA": 1.4923716596941703, "ESBRIET": 1.6241920724616092, "ESOMEPRAZOLE": 1.345989474032498, "EVENITY": 3.477571262860085, "EVISTA": 5.409031730854047, "EXFORGE": 3.153278703002161, "EYLEA": 4.654098604584848, "FEBUXOSTAT": 2.759200813196794, "FESOTERODINE": 12.30039743852318, "FORSTEO": 1.939509321970052, "GALAFOLD": 4.285712575350503, "GALVUS": 1.9137143321540924, "HUMALOG": 4.379197878243405, "IBRANCE": 1.519169086124943, "ICLUSIG": 3.155666396707232, "INCRUSE": 1.0477517288132543, "INLYTA": 1.7174075304687235, "INSULIN": 1.8276575704595324, "INTEGRILIN": 1.6593422757281358, "INVOKANA": 1.3855288005560586, "ISENTRESS": 1.4921252034640908, "JANUMET": 2.4021105954716453, "JANUVIA": 2.068911264369683, "JARDIANCE": 4.093612452643347, "KIVEXA": 1.0532550488595398, "LANTUS": 5.316474719448628, "LATUDA": 1.0959966477691063, "LEVEMIR": 3.930474651540381, "LIXIANA": 4.711151968334206, "LYRICA": 1.3763279847266536, "MEMANTINE": 2.2962330139238576, "MEPOLIZUMAB": 1.437331741446768, "MICARDIS": 1.8494512515301116, "MIMPARA": 1.8538776554381584, "MIRCERA": 1.081440207193554, "MIXTARD": 1.5370019255850909, "NILOTINIB": 2.715151057151425, "NINLARO": 1.014630989446318, "NIVOLUMAB": 1.21979056258211, "NOVOSEVEN": 4.332363581482891, "NPLATE": 2.218281948621779, "OFEV": 1.8595994068497943, "ONGLYZA": 1.3880131525618944, "PANTOPRAZOLE": 1.2311826421868854, "PIRFENIDONE": 2.394732718545204, "PLAVIX": 6.141716358074126, "PRADAXA": 3.0720222914856365, "PRAXBIND": 3.7347593578278153, "PROTELOS": 1.2956616858715806, "RANOLAZINE": 3.826047687601473, "RAPAMUNE": 2.4515180498800824, "RASBURICASE": 3.08446484991966, "RASILEZ": 3.022984048799418, "REVATIO": 1.7945321889160628, "RINVOQ": 2.494039019276256, "ROSIGLITAZONE": 22.750281720428145, "SIMPONI": 1.0447014596049482, "SKYRIZI": 1.9008105158817408, "STELARA": 1.6852073822120237, "TASIGNA": 3.744346334720356, "TEKTURNA": 2.6343060876584965, "TESTOSTERONE": 4.358027315645759, "THALIDOMIDE": 1.280711341331425, "TIVICAY": 1.1752680078802706, "TOUJEO": 2.801682993135879, "TOVIAZ": 2.4617214737178603, "TOZINAMERAN": 1.030174064758903, "TRELEGY": 3.22997959908206, "TREMFYA": 1.7813561910668922, "TRESIBA": 1.0731734535114787, "TRULICITY": 2.0985474120593346, "VALSARTAN": 1.6287680693783977, "VELTASSA": 2.253586628905528, "VIAGRA": 4.845752750982413, "VICTOZA": 1.4673127344323575, "VOTRIENT": 1.5623076212167208, "XARELTO": 1.8493104720330344, "XELJANZ": 1.6791861704589277, "XOLAIR": 1.1153736239916787, "XTANDI": 2.005672820550863, "ZYPREXA": 1.1342562557893556}
\ No newline at end of file
+{"null": 1.1938336549818236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1665.json
index 2259a56298b..45232f68504 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1665.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1665.json
@@ -1 +1 @@
-{"AVANDAMET": 21.709715064212386, "AVANDIA": 13.309273364352492, "BUPRENORPHINE": 4.797888877720484, "CICLOSPORIN": 2.3375258538363157, "CLOPIDOGREL": 1.4167244702111847, "ELIQUIS": 2.1666553019584005, "HUMALOG": 1.465824562115332, "VIAGRA": 7.518862846846932, "ZOSTAVAX": 2.623814105010817, "ZYPREXA": 3.912715065415471, "null": 1.4960646512891436}
\ No newline at end of file
+{"SOLIRIS": 101.25475683678924, "null": 0.5081242998856894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1666.json
index ef4d9966beb..0d72e1b4fe5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1666.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1666.json
@@ -1 +1 @@
-{"SODIUM": 1687.92266617122}
\ No newline at end of file
+{"SOLIRIS": 55.95308771719836, "null": 0.2351767091317721}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1667.json
index 23eab8e3cbe..66e1285b8e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1667.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1667.json
@@ -1 +1 @@
-{"ZOSTAVAX": 73.72581199397733, "null": 1.1555891604403314}
\ No newline at end of file
+{"ABACAVIR": 0.290690775615327, "ABILIFY": 0.3005237430677717, "ACTOS": 2.7903965803440096, "AFINITOR": 3.5360629969159, "ALEMTUZUMAB": 1.152002646928802, "ARAVA": 0.1502814578921546, "ASPARAGINASE": 2.303101354047261, "ATAZANAVIR": 1.279157168368252, "AVANDIA": 0.4980535284173762, "AZACITIDINE": 1.4861964331334914, "AZATHIOPRINE": 0.9126469283448072, "BARACLUDE": 2.491706391072863, "BAVENCIO": 4.978233153990103, "BEVACIZUMAB": 1.4850264475679638, "BOSULIF": 1.688029977473437, "BRAFTOVI": 1.3619360615701486, "BRUKINSA": 15.394581403588946, "BUSULFAN": 3.0034501941004965, "CABOMETYX": 0.8800977810878108, "CANCIDAS": 10.262490026935035, "CAPECITABINE": 1.4015249885854828, "CARMUSTINE": 8.406682324824763, "CELLCEPT": 1.8604390445497108, "CHAMPIX": 0.1737107705708528, "CICLOSPORIN": 4.848026347761059, "CLOPIDOGREL": 0.2941468881122486, "COMBIVIR": 4.3035728758008736, "COMIRNATY": 0.118001472373265, "COMTAN": 2.8737626370562177, "COSENTYX": 0.4699150868748838, "COTELLIC": 4.249604998943078, "CRIXIVAN": 2.4873491159608374, "CUBICIN": 1.526626522088414, "CYMBALTA": 0.1775597505049288, "CYTARABINE": 8.172529681973671, "DABRAFENIB": 6.416465175399551, "DEXAMETHASONE": 2.8880169913793625, "DOXORUBICIN": 4.7655335060127015, "ELIQUIS": 0.1731837484634291, "ENTRESTO": 0.5959194408220448, "EPIVIR": 5.323866467033643, "EVEROLIMUS": 3.642831200084728, "EXJADE": 4.1037315986560206, "FASLODEX": 1.145080392357668, "FENTANYL": 0.5903123343034137, "FILGRASTIM": 2.6534633858601646, "GAZYVARO": 5.683274155706481, "GLIVEC": 6.630800153905613, "HERCEPTIN": 2.124833871112354, "HUMAN": 1.9031884928806684, "HYCAMTIN": 7.454170133962839, "IBRANCE": 0.4220289310890486, "IBRUTINIB": 11.660909976688318, "IBUPROFEN": 0.8186687545349782, "ICLUSIG": 1.1256082335053894, "INLYTA": 0.5181484057229363, "INTRONA": 2.900355183044035, "IPILIMUMAB": 1.4538868825064322, "JAKAVI": 12.778400709553582, "KAFTRIO": 1.1751423971902073, "KALETRA": 2.6986942215149314, "KEPPRA": 0.400412438356998, "KEYTRUDA": 1.124724176346633, "KISQALI": 1.422874875371557, "KYMRIAH": 6.22835359434703, "LEFLUNOMIDE": 1.424424887081369, "LEMTRADA": 2.383071106755942, "LENALIDOMIDE": 8.227162702034047, "LENVIMA": 1.0798321676633589, "LEVOFLOXACIN": 2.0997772187154022, "LYRICA": 0.5963444741720038, "MANNITOL": 10.213913209647584, "MEKINIST": 4.526756779370326, "MELPHALAN": 4.079842593434381, "METHOTREXATE": 1.264977830515858, "MICARDIS": 1.711205961707358, "NEULASTA": 1.1961317851686952, "NEXAVAR": 1.80312749457287, "NPLATE": 1.341153490710769, "OLANZAPINE": 1.6941889342741208, "OPDIVO": 1.879522624511642, "PEGASYS": 0.3484081169237442, "PEGFILGRASTIM": 18.46529312678713, "PEGINTERFERON": 1.2622244590999838, "PEGINTRON": 0.4103102297685717, "PEMBROLIZUMAB": 0.8367883246812922, "PLAVIX": 0.9245797731465372, "PRIVIGEN": 3.3069831974813115, "PROTELOS": 4.881780841508879, "RASBURICASE": 23.64673172684285, "RIBAVIRIN": 1.594657711450452, "RINVOQ": 0.9631334958923592, "RITUXIMAB": 3.1363896029386646, "ROACTEMRA": 1.3370736820317397, "RUXOLITINIB": 5.94750162090218, "SOLIRIS": 35.56879967520331, "SPIKEVAX": 0.0369215093673124, "STIVARGA": 2.5588509426621973, "SUTENT": 1.8791154405968389, "TAMIFLU": 1.481851908235596, "TASIGNA": 1.109255794063402, "TORISEL": 2.6574965554513503, "TOZINAMERAN": 0.0415725380969655, "TRACLEER": 0.983309272374668, "VENCLYXTO": 5.487730788230329, "VENETOCLAX": 7.461897343470305, "VFEND": 2.3278358521066296, "VIAGRA": 0.9063215207533144, "VIRAMUNE": 4.683304377800899, "VOTRIENT": 1.9667630988706053, "XALKORI": 1.7743416382209465, "XELJANZ": 0.1837475031703119, "XOFIGO": 2.102879681179484, "XOLAIR": 0.2675504946497229, "ZIAGEN": 5.124833864366321, "ZYPREXA": 2.387142234485301, "null": 1.954473326998722}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1668.json
index 5f62c52503b..69b39834bc7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1668.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1668.json
@@ -1 +1 @@
-{"GARDASIL": 240.088482691558}
\ No newline at end of file
+{"COMIRNATY": 0.2872647933273635, "JANUMET": 52.0267677714317, "SPIKEVAX": 3.586126415458252, "null": 0.5457126332908323}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1669.json
index 973585f9b57..96b3835d685 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1669.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1669.json
@@ -1 +1 @@
-{"NAGLAZYME": 1075.072725692061}
\ No newline at end of file
+{"null": 0.9994281994518696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/167.json
index 77d5ee89dbd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/167.json
@@ -1 +1 @@
-{"HUMALOG": 3.133679690100156, "IPILIMUMAB": 33.41518997901263, "KEYTRUDA": 6.864005961426807, "MEPOLIZUMAB": 45.041835121308175, "NUCALA": 54.51033010058474, "OPDIVO": 10.721286382533403}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1670.json
index 86f5177e2ad..117b332867c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1670.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1670.json
@@ -1 +1 @@
-{"BUSULFAN": 6.993450106179345, "GARDASIL": 222.5649834247455, "LAMIVUDINE": 17.016252262998087, "LEMTRADA": 11.28652655035136, "SILGARD": 309.445057320626, "STELARA": 7.805708883577505}
\ No newline at end of file
+{"null": 2.1482279923668317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1671.json
index ecc58252df6..8174ca70a9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1671.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1671.json
@@ -1 +1 @@
-{"NORVIR": 116.0334952499294, "null": 1.7398895426949097}
\ No newline at end of file
+{"ABACAVIR": 5.990125632948553, "ARIPIPRAZOLE": 1.346298400491875, "ATAZANAVIR": 11.722222357689844, "BARACLUDE": 9.249199967021614, "BIKTARVY": 2.7151965260776745, "BUDESONIDE": 30.414420167968856, "CICLOSPORIN": 0.6342407288976104, "COMBIVIR": 15.868558367731406, "COMIRNATY": 0.0523244801087504, "CRIXIVAN": 44.87874077578777, "CYTARABINE": 3.445692605092733, "DEXAMETHASONE": 5.0677640578044105, "EFAVIRENZ": 5.9203348935162206, "EMPAGLIFLOZIN": 9.599695114040616, "ENFUVIRTIDE": 134.77730553200527, "ENTRESTO": 1.7054109868756293, "EPIVIR": 36.96344941393885, "FENTANYL": 2.0524849491493886, "FORXIGA": 1.6326715356008077, "HYDROCORTISONE": 3.504200060523153, "IBUPROFEN": 2.1723422195706834, "INOTUZUMAB": 140.35975034671853, "INVIRASE": 48.75450212338035, "JANUMET": 2.064220931679165, "JANUVIA": 1.5686596496421776, "JARDIANCE": 1.3043792467840174, "KALETRA": 6.32462536540212, "LAMIVUDINE": 18.976647894607986, "LANTUS": 0.4618873834403008, "LEVETIRACETAM": 1.39614073361391, "MANNITOL": 36.55478555195216, "METFORMIN": 12.380623713043832, "MIDAZOLAM": 3.991761117745214, "NEVIRAPINE": 13.854278052634928, "NUCALA": 40.23136874108019, "OLANZAPINE": 1.2343873986151286, "OPSUMIT": 1.2027992669579617, "SAQUINAVIR": 300.6426071405326, "SPIKEVAX": 0.045284820677842, "TOZINAMERAN": 0.1739797589164454, "TRUVADA": 0.235873262863121, "VIREAD": 3.920168711991569, "ZERIT": 53.96786311775678, "null": 1.4104097469075465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1672.json
index a48827b4296..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1672.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1672.json
@@ -1 +1 @@
-{"null": 1.5922577473745012}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1673.json
index e44cd3d7880..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1673.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1673.json
@@ -1 +1 @@
-{"ATRIPLA": 3.467042123751412, "COMIRNATY": 1.781213723493346, "TRUVADA": 1.486700068113858, "ZOSTAVAX": 33.08728414826788}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1674.json
index a4e9739efff..7df0fc2afdb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1674.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1674.json
@@ -1 +1 @@
-{"ATRIPLA": 6.869822920980888, "NAGLAZYME": 141.75257451018143, "TRUVADA": 3.077848270211893, "ZOSTAVAX": 15.012093805560996}
\ No newline at end of file
+{"ARIXTRA": 44.05024982817037, "BRILIQUE": 20.385836006284023, "BYETTA": 4.24326773698921, "CLOPIDOGREL": 42.386385326079576, "COMIRNATY": 0.0592644307932906, "EFIENT": 16.77769326125134, "ELIQUIS": 11.630048139793322, "ENOXAPARIN": 6.090085565559107, "JANUMET": 1.8432457595517768, "JANUVIA": 2.7426803045975863, "LIXIANA": 7.305957493458125, "NEXAVAR": 1.2390250262150293, "PLAVIX": 29.42809605238273, "PRADAXA": 35.61284548976116, "SPIKEVAX": 0.0431705623339625, "STIVARGA": 1.4135485083701214, "SUTENT": 0.2585556219779419, "TICAGRELOR": 50.74725054408197, "VAXZEVRIA": 0.033061724782547, "XARELTO": 39.12333146256927, "null": 1.3706477264172945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1675.json
index bd4005bc68a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1675.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1675.json
@@ -1 +1 @@
-{"ATRIPLA": 5.562828680428085, "ELIQUIS": 4.371814168631916, "EVISTA": 19.61003571433293, "FORSTEO": 4.110897482964797, "HUMALOG": 3.620615356046761, "HUMIRA": 4.391541358766919, "IBRANCE": 1.9848113615495129, "KEPPRA": 2.0915832524353646, "LANTUS": 2.040806486824206, "STELARA": 2.2355472941953085, "STRIBILD": 4.16721827273374, "TRUVADA": 3.1802554862285124, "VIAGRA": 8.823489078847313, "null": 1.0671932392559609}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1676.json
index c57f2899c11..65ca52c36c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1676.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1676.json
@@ -1 +1 @@
-{"GARDASIL": 20.396950832593944}
\ No newline at end of file
+{"null": 3.3787377995981838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1677.json
index e25af6bc3b5..534819f1711 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1677.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1677.json
@@ -1 +1 @@
-{"COMIRNATY": 3.553588392658761, "GARDASIL": 3.1818444584995884, "VAXZEVRIA": 1.026484610615432}
\ No newline at end of file
+{"BUSULFAN": 295.5451688894767, "DOXORUBICIN": 382.81432429938366, "null": 0.5499069498268838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1678.json
index 3c2520e2496..be7e80efa32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1678.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1678.json
@@ -1 +1 @@
-{"AIMOVIG": 71.70637535375774, "COVID19": 1.2758432990941224}
\ No newline at end of file
+{"null": 0.7965586274764056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1679.json
index bac5b9d1479..1244b179cd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1679.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1679.json
@@ -1 +1 @@
-{"CELLCEPT": 4.43430947844659, "CIMZIA": 1.4601266447424712, "GARDASIL": 25.623608003271865, "SIMPONI": 2.780282032043905, "STELARA": 2.134880953971502, "XELJANZ": 1.9518093053339132, "null": 2.261405827013813}
\ No newline at end of file
+{"AFINITOR": 2.228610808425931, "ALIMTA": 3.086813710840838, "AMINOSALICYLIC": 18.28801422372262, "BEDAQUILINE": 45.58691371230553, "BENZODIAZEPINES": 78.41658415073468, "CABOMETYX": 4.088506210703563, "CAPECITABINE": 8.295574104411465, "CICLOSPORIN": 1.547435192013151, "COMIRNATY": 0.0186896171420849, "DOXORUBICIN": 7.547550354952121, "ELIQUIS": 0.5744287732094715, "EMEND": 14.809533992840915, "EVEROLIMUS": 13.762875400735172, "FENTANYL": 2.521351304990337, "FILGRASTIM": 14.911725946718452, "FIRDAPSE": 9.202451250214928, "HERCEPTIN": 4.846376007144799, "HUMALOG": 1.5667283826620455, "IBRANCE": 1.9631547147166524, "INLYTA": 2.6643968558096285, "JANUMET": 3.2420097159105232, "KEYTRUDA": 1.4228813083923677, "LANTUS": 0.7250409712422754, "LEVOFLOXACIN": 1.5730407715227628, "MIDAZOLAM": 10.38566124554869, "OPSUMIT": 3.040348525180184, "PANTOPRAZOLE": 15.20985126319659, "PEGASYS": 0.5594187260329851, "PEGINTRON": 1.5767766998046715, "PLAVIX": 1.0415489988521027, "RUBRACA": 33.12169306081485, "SOLIRIS": 1.7562493771222858, "SUTENT": 3.281013450172523, "TACROLIMUS": 14.473511721623495, "TOZINAMERAN": 0.2141043947989531, "VECTIBIX": 23.500793987521423, "VELTASSA": 11.610696779373075, "VFEND": 2.2536547217379588, "VOTRIENT": 1.6561827793239183, "XELJANZ": 0.6732966029475806, "ZOSTAVAX": 1.078875500968098, "null": 0.8904434275962744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/168.json
index 78f791b46ee..e6f2de618a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/168.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 9.86493757326402, "CAPECITABINE": 12.117343663239335, "CELLCEPT": 4.048724956322976, "CIMZIA": 1.8538260478681297, "DOCETAXEL": 12.615312877641166, "JAKAVI": 6.82629803147627, "MYCOPHENOLATE": 14.050966833140434, "PEGASYS": 1.3078671130811614, "PEMBROLIZUMAB": 13.406164798044175, "PEMETREXED": 29.411759205478, "STELARA": 4.438624776624523}
\ No newline at end of file
+{"VALSARTAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1680.json
index 8b253da507a..dd54a85e147 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1680.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1680.json
@@ -1 +1 @@
-{"GARDASIL": 171.54689905781538}
\ No newline at end of file
+{"ABATACEPT": 15.274339002351184, "ARAVA": 9.49072966429159, "ARIPIPRAZOLE": 37.46717710765861, "ENBREL": 8.455616686934539, "INTELENCE": 196.05906906058885, "null": 0.9650844660712016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1681.json
index 36d2a485928..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1681.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1681.json
@@ -1 +1 @@
-{"GARDASIL": 21.18155176500074, "RITUXIMAB": 23.69189430293826}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1682.json
index 9deef985af7..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1682.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1682.json
@@ -1 +1 @@
-{"null": 1.5239202029864345}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1683.json
index 7c4fdfbde97..b440d668411 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1683.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1683.json
@@ -1 +1 @@
-{"null": 2.2142953271576955}
\ No newline at end of file
+{"null": 8.820566445208117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1684.json
index d4ccf3c855d..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1684.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1684.json
@@ -1 +1 @@
-{"null": 1.5866082288418275}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1685.json
index 2f2796311e4..6cf6bf77fc7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1685.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1685.json
@@ -1 +1 @@
-{"KAFTRIO": 247.67653199874184, "ZOSTAVAX": 8.409123794092395}
\ No newline at end of file
+{"null": 1.4737406591636295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1686.json
index e37d477aad3..3831b02e268 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1686.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1686.json
@@ -1 +1 @@
-{"BRIVIACT": 211.97863648775075, "KEPPRA": 34.78788256257526, "LEVETIRACETAM": 33.00445893528884, "VIMPAT": 109.98365812863648, "null": 1.3265332732662578}
\ No newline at end of file
+{"COMIRNATY": 0.2790127772394333, "null": 3.0853111546575773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1687.json
index 11e8c1c1157..ebb10f44a47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1687.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1687.json
@@ -1 +1 @@
-{"null": 1.840512258020596}
\ No newline at end of file
+{"CETRORELIX": 3972.331408983344, "COMIRNATY": 0.1488003810621609, "FASLODEX": 18.732033865902597, "null": 3.7099839260880048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1688.json
index f452978715e..a96a50dd56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1688.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1688.json
@@ -1 +1 @@
-{"PEGASYS": 1.5880835679966507, "SUTENT": 1.5487636994180585, "XELJANZ": 3.9299829795286216, "null": 1.7190545766100764}
\ No newline at end of file
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1689.json
index 3c03c360a68..a29e5ca4169 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1689.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1689.json
@@ -1 +1 @@
-{"AFINITOR": 2.939501014896292, "GARDASIL": 1.786348115569935, "IBRANCE": 1.7469929662671375, "PEGASYS": 2.70185097197796, "PEGINTRON": 2.800322583820305, "ROTATEQ": 8.18730910684673, "SUTENT": 5.867829370594369, "null": 1.6212239606283405}
\ No newline at end of file
+{"null": 3.5734331068466294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/169.json
index 31305b9e249..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/169.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 30.191752592329667, "COSENTYX": 2.96946792068669, "ENTYVIO": 13.491180964646931, "IRINOTECAN": 17.633609204137816, "RINVOQ": 8.737161144514905, "ROACTEMRA": 13.215535321994038, "SIMPONI": 4.228186817157243, "STELARA": 14.127170974809578, "STIVARGA": 37.6148695725063}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1690.json
index 1667f587253..340b6cebed3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1690.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1690.json
@@ -1 +1 @@
-{"AMIKACIN": 8.653335205272196, "CHAMPIX": 1.074534934671723, "CLOPIDOGREL": 1.1318971276469714, "IBRANCE": 1.846856856867941, "KEYTRUDA": 2.051553465820028, "METHOTREXATE": 5.041176657886832, "NEXAVAR": 1.8734533819168997, "OLYSIO": 17.171008689501928, "PLAVIX": 1.253382583272586, "SUTENT": 1.6781614581205055, "VFEND": 13.293593542138376, "null": 1.9243950116099056}
\ No newline at end of file
+{"ARIPIPRAZOLE": 20.72281943258732, "CLOPIDOGREL": 16.90808374339688, "OLANZAPINE": 9.230638015134318, "null": 1.3781087290446248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1691.json
index 9b047e039f0..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1691.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1691.json
@@ -1 +1 @@
-{"null": 7.515696281640654}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1692.json
index 936e2618471..af3e77e53af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1692.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1692.json
@@ -1 +1 @@
-{"null": 4.143453142560489}
\ No newline at end of file
+{"VAXZEVRIA": 7.211055202161015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1693.json
index e3bb54664ce..44317cbee65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1693.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1693.json
@@ -1 +1 @@
-{"null": 6.389045994236043}
\ No newline at end of file
+{"JARDIANCE": 90.65316679319876, "null": 0.5703274743427723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1694.json
index 6722e1058b6..bec3a850a08 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1694.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1694.json
@@ -1 +1 @@
-{"null": 5.5697481350599}
\ No newline at end of file
+{"HYDROCORTISONE": 10.148701302954477, "IBUPROFEN": 8.454115236572726, "INSULIN": 4.482496793435725, "JARDIANCE": 3.2072399244159686, "LACOSAMIDE": 52.59603691086101, "LEVETIRACETAM": 92.12923947398713, "MIDAZOLAM": 11.783423627842764, "null": 1.903515983833536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1695.json
index d9807fef5e4..5f086bb2c69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1695.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1695.json
@@ -1 +1 @@
-{"null": 4.64777118174146}
\ No newline at end of file
+{"COMIRNATY": 0.3644910280330842, "IBUPROFEN": 53.51177802850528, "VAXZEVRIA": 0.4492836804310309, "null": 1.050468675083371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1696.json
index 742356f565c..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1696.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1696.json
@@ -1 +1 @@
-{"null": 4.362431881502759}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1697.json
index b3d2aefa84d..a607b526375 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1697.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1697.json
@@ -1 +1 @@
-{"null": 1.8216547341603908}
\ No newline at end of file
+{"MIMPARA": 853.2897477860769, "null": 1.4266968591827691}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1698.json
index 54f79ee8b6e..b9d4ade1504 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1698.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1698.json
@@ -1 +1 @@
-{"null": 8.0694678103627}
\ No newline at end of file
+{"ABATACEPT": 21.408313323844627, "ADALIMUMAB": 29.74465274868898, "APREMILAST": 77.84293364138503, "ARAVA": 7.521311168320196, "CICLOSPORIN": 5.302497415791162, "ENBREL": 73.9334437838053, "FORSTEO": 11.281123712948332, "MIMPARA": 68.61286924326238, "null": 0.2034994644887112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1699.json
index 98602c63b01..870f592663b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1699.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1699.json
@@ -1 +1 @@
-{"null": 2.670761264030718}
\ No newline at end of file
+{"ARANESP": 8.432417403807639, "BONVIVA": 18.091390498298043, "CINACALCET": 103.91006500180652, "EVENITY": 36.13298525304862, "FORSTEO": 24.425864054447946, "MICARDIS": 16.67822070613794, "MIMPARA": 881.6131772894765, "PROLIA": 80.47040917665356, "TRUVADA": 1.2160694582387357, "null": 1.5453990120327052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/17.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/17.json
index 125d27c9550..9cf2cbedaea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/17.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/17.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.355431207537834, "ADENURIC": 1.0073809115924246, "ADVAGRAF": 1.7493201435672638, "AERIUS": 1.337392854487326, "AFINITOR": 1.0931365917001168, "AFLIBERCEPT": 1.1133458336129762, "AGOMELATINE": 1.342208607217382, "AIMOVIG": 1.5027330703695467, "ALIGN": 6.253153425659666, "ALOXI": 1.7787949266472878, "AMGEVITA": 4.005379349207265, "AMINOSALICYLIC": 3.3437141919860025, "APIXABAN": 1.0898601232528913, "ARANESP": 4.990047295506409, "ASPARAGINASE": 1.667065502382454, "ATEZOLIZUMAB": 3.42886689881974, "AVAMYS": 1.5216945334825325, "AVASTIN": 1.313805881698355, "AZATHIOPRINE": 1.222428281578653, "BEVACIZUMAB": 1.071878708377518, "BIKTARVY": 1.3330161565903105, "BINIMETINIB": 1.485832448713471, "BONVIVA": 1.819192580710421, "BOSULIF": 1.5472515426254951, "BOSUTINIB": 2.2044212826714547, "BRAFTOVI": 1.5598386068988894, "BRINTELLIX": 1.0773155450066512, "BRUKINSA": 1.4676479163965193, "BUDESONIDE": 2.7281098337410583, "BYDUREON": 1.2917043438919438, "BYETTA": 1.6477669804551822, 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1.55698494849314, "EPOETIN": 4.483985858295148, "ERENUMAB": 4.317675810106594, "ESMYA": 1.6492476363319404, "ESOMEPRAZOLE": 1.0761044272437252, "EUCREAS": 2.796479139298581, "EVRA": 1.53894285763319, "EXJADE": 2.135090031256191, "EXVIERA": 1.787931712236852, "FIDAXOMICIN": 1.7326462912849128, "FLEBOGAMMA": 1.1643695453381668, "FLUTICASONE": 1.8993024702969536, "FOLLITROPIN": 6.44377869713319, "FORXIGA": 1.2057919652777942, "GALVUS": 1.5743350765154502, "GARDASIL": 2.184502074062689, "GLIVEC": 1.5199641125061054, "GONALF": 7.321081890619816, "HERBAL": 3.9519428340301377, "HEXYON": 1.1840555652889548, "HUMIRA": 1.3689159808764668, "HYCAMTIN": 1.101359401819601, "HYQVIA": 1.6213278356600058, "IBUPROFEN": 1.0192781907316029, "ICLUSIG": 1.628469316755557, "IDACIO": 1.1720715234816708, "INDINAVIR": 1.660981642775306, "INFLECTRA": 1.6188633275225166, "INFLIXIMAB": 1.7181202455629665, "INTELENCE": 1.7884709153513934, "INVIRASE": 1.4931803658720586, "IRINOTECAN": 1.872806541538777, "JANUMET": 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"SILGARD": 1.4491329571424811, "SITAGLIPTIN": 1.6154187350290872, "SOLIRIS": 1.6458817206900769, "SORAFENIB": 1.1474555283821348, "STAVUDINE": 3.699398444925811, "STELARA": 1.1668299720202226, "STIVARGA": 1.3438926419503243, "SUNITINIB": 1.461852277437763, "SUTENT": 1.0414475146115234, "TAMIFLU": 1.5651664939168417, "TASIGNA": 1.3510603172415765, "TAXOTERE": 1.0170505051359178, "TEDUGLUTIDE": 1.570011246069949, "TEGADERM": 2.595551872054118, "TERIFLUNOMIDE": 1.021400569591688, "TICAGRELOR": 1.0257873147076295, "TRIUMEQ": 1.6475140680550224, "TRODELVY": 1.91606473228231, "TRULICITY": 3.620120907609257, "TWINRIX": 1.3330933554549145, "UROREC": 1.114193518519911, "VEDOLIZUMAB": 4.741973448856593, "VELMETIA": 3.4784539042357245, "VERZENIOS": 4.211797262084774, "VICTOZA": 2.966259794804712, "VICTRELIS": 2.182743330766667, "VOTRIENT": 1.2385179616745736, "XELODA": 1.388962777003773, "YERVOY": 1.100164328034369, "ZARZIO": 1.6890682893349318, "ZEPATIER": 1.0084584924902886, "ZIAGEN": 4.138599471559138, "ZYLLT": 2.536820778793655, "null": 1.219161536318078}
\ No newline at end of file
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/170.json
index a3cd9e8e2f0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/170.json
@@ -1 +1 @@
-{"GARDASIL": 54.1932788499651}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1700.json
index 7a409b100bc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1700.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1700.json
@@ -1 +1 @@
-{"SUBSTANCE": 19458.108500057097, "null": 2.411107289406896}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1701.json
index 7bcc8d93b84..bafa429822b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1701.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1701.json
@@ -1 +1 @@
-{"DOCETAXEL": 12.074243086951403, "DOXORUBICIN": 24.95755586541064, "HIZENTRA": 9.502185639318814, "ICLUSIG": 14.359773184809605, "JANUMET": 7.72397513842111, "KEYTRUDA": 5.387021727562197, "MEPOLIZUMAB": 5.6393262222795775, "OPSUMIT": 8.046396699684333, "SIMPONI": 8.179157021167258, "STELARA": 3.697481047054121, "TRACLEER": 8.63911813377018, "TRELEGY": 8.961101107335706, "null": 1.4763171879526458}
\ No newline at end of file
+{"null": 1.007369280660236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1702.json
index e43b296ab92..947e5b5df5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1702.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1702.json
@@ -1 +1 @@
-{"COVID19": 1.709603640041359, "SPIKEVAX": 20.15192392980808}
\ No newline at end of file
+{"ADALIMUMAB": 0.4157026079845408, "ADEFOVIR": 505.4596392655991, "AFINITOR": 2.572635948662627, "ATAZANAVIR": 10.958902756132234, "ATRIPLA": 0.9861941295605078, "BENZODIAZEPINES": 130.45498989165938, "COMIRNATY": 0.0568823567082195, "EMTRIVA": 73.82414740774543, "ENTECAVIR": 78.1716564135315, "EVEROLIMUS": 20.200027659713385, "EXJADE": 5.782874285663376, "HEPSERA": 391.6936320071961, "KYMRIAH": 7.981567287742407, "MIMPARA": 22.28517840000421, "NEXAVAR": 1.6763105635214193, "NORVIR": 24.19163771582701, "OLANZAPINE": 1.7641158783895026, "PANTOPRAZOLE": 14.0116589045849, "STRIBILD": 3.7996629517840974, "SUTENT": 0.9871430502832008, "TENOFOVIR": 85.43367228710261, "TRUVADA": 6.338317095881918, "VIREAD": 57.434493122318216, "null": 0.5678961361794542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1703.json
index 77a110cca8d..618c962f89c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1703.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1703.json
@@ -1 +1 @@
-{"ALENDRONATE": 271.4723925592004, "APIXABAN": 19.449427688773334, "BUDESONIDE": 50.14859097325539, "CICLOSPORIN": 1.741068469818529, "ELIQUIS": 1.4708858316519946, "IRESSA": 4.587924595632598, "LEVOFLOXACIN": 1.5396349865601098, "MEPOLIZUMAB": 3.871594276572379, "NUCALA": 65.1313711858788, "PRIALT": 105.50992778025244, "SPIKEVAX": 1.5750082994039023, "TAMIFLU": 2.563153017956776, "XOLAIR": 1.062777139461759}
\ No newline at end of file
+{"ARANESP": 413.7856330926713, "DARBEPOETIN": 230.84390741085903, "ENTRESTO": 4.185427107854594, "FLUTICASONE": 92.15110845501242, "INSULIN": 4.646976453913692, "MICARDIS": 8.189298526655117, "MIMPARA": 26.900931614474924, "RASBURICASE": 146.31354052446963, "SOLIRIS": 3.859792334823805, "VENCLYXTO": 19.549374448162773, "VENETOCLAX": 35.59914642081516, "VILDAGLIPTIN": 65.6311665791848, "null": 0.5341504634135774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1704.json
index 987d00d2136..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1704.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1704.json
@@ -1 +1 @@
-{"SPIKEVAX": 46.30816705880069}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1705.json
index 22b64792b81..6c54a20720a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1705.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1705.json
@@ -1 +1 @@
-{"COVID19": 4.288963038675858, "TOZINAMERAN": 5.386129763745794}
\ No newline at end of file
+{"COMIRNATY": 0.0555415090154741, "ENTRESTO": 4.0394517099962135, "KEYTRUDA": 1.4723586300233171, "LANTUS": 2.042017731073916, "PEGASYS": 2.820045882152264, "SUTENT": 1.1413404016930162, "VELTASSA": 56.25309808655963, "ZOSTAVAX": 3.1387644878879013, "null": 1.3322463943645058}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1706.json
index 8660042d197..3edc6a4de7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1706.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1706.json
@@ -1 +1 @@
-{"ACLIDINIUM": 1.9551090084266145, "ALEMTUZUMAB": 1.0184624762689731, "ALISKIREN": 5.893821820609416, "ANORO": 1.5859293570802309, "ANTIHYPERTENSIVES": 5.198410548048072, "APIXABAN": 1.5826326951750205, "AVAMYS": 1.6104651758570616, "BETMIGA": 1.385258291707799, "BREXPIPRAZOLE": 2.948200604974316, "BRILIQUE": 1.0632482143908344, "BUDESONIDE": 4.061523130104637, "CAELYX": 2.7024169928679136, "CHAMPIX": 1.147694537346575, "CHOLESTAGEL": 14.618825869856924, "CLOPIDOGREL": 1.3565147046344417, "COMIRNATY": 2.172128506329042, "COVID19": 1.0613350723438404, "DARZALEX": 2.702118680198537, "DUORESP": 2.563358349095402, "DUPILUMAB": 2.332590888266992, "DUPIXENT": 2.4467281931639677, "EVUSHELD": 2.5508285586151263, "FASENRA": 2.2992454139522245, "FLEBOGAMMA": 3.878466862624317, "FLUTICASONE": 5.893763548734202, "FOLLITROPIN": 6.415142431221763, "GAZYVARO": 1.625363920897142, "GLYCOPYRRONIUM": 8.695522308024007, "GONALF": 3.680840228487849, "HERCEPTIN": 1.0208564065772716, "HYDROCORTISONE": 1.3758514776712978, "INCRUSE": 2.095267461819474, "INSULIN": 1.2934058574272105, "JCOVDEN": 1.7457641547648888, "KAFTRIO": 1.7223829473452936, "KALYDECO": 2.281922482141893, "KIOVIG": 2.290970881067411, "KUVAN": 1.2576075832616511, "LEMTRADA": 1.8062706604523429, "LEVOFLOXACIN": 1.2614083169067123, "LUVERIS": 6.0168872954927695, "MEPOLIZUMAB": 3.279275105718388, "MIRCERA": 1.573135860288231, "NUCALA": 5.256251788860213, "OBINUTUZUMAB": 2.088978036511576, "OMALIZUMAB": 3.2779812215098, "ONCASPAR": 1.183507153063605, "OPSUMIT": 1.3515379816947644, "ORKAMBI": 4.254297981532559, "OZEMPIC": 1.9002620548213145, "PACLITAXEL": 1.2416653139936382, "PANTOPRAZOLE": 1.084342834984244, "PERJETA": 2.7412139608184813, "PERTUZUMAB": 1.344742110897082, "PRIVIGEN": 1.800802494579506, "RANEXA": 1.0366633536786491, "RAPISCAN": 8.074860891370413, "RELVAR": 2.308950098146111, "RIXATHON": 2.315525257279948, "SEEBRI": 7.563712124875466, "SILDENAFIL": 1.4257480872382282, "SOMAVERT": 3.042157678075463, "SPIKEVAX": 1.4513397741551852, "TELMISARTAN": 3.2618584404812383, "TICAGRELOR": 9.460401999354136, "TOBI": 8.083505292931292, "TORISEL": 1.1116026855981482, "TOZINAMERAN": 2.0088912106510084, "TRACTOCILE": 2.403972557655992, "TRELEGY": 1.4293437133276898, "UMECLIDINIUM": 4.950594641698073, "UROREC": 1.4522580904133051, "VALSARTAN": 1.9277126814450505, "XOLAIR": 4.4194928818101, "ZARZIO": 1.0403187370805962}
\ No newline at end of file
+{"ABILIFY": 0.5747186489025983, "ACTOS": 3.0936523112478187, "ADALIMUMAB": 0.1359971759385928, "ADEMPAS": 3.204998557492243, "AFINITOR": 2.130360092139089, "AIMOVIG": 0.3018160720014885, "AMINOSALICYLIC": 4.896853183101811, "ARAVA": 0.1324475570873894, "AUBAGIO": 1.1334277074603183, "BEDAQUILINE": 14.423660005932955, "BENLYSTA": 1.5495535968811234, "BENZODIAZEPINES": 18.90217070148996, "BUDESONIDE": 11.535205599183673, "BYETTA": 1.2392562650010848, "CABOMETYX": 1.7541082887916717, "CANCIDAS": 3.486112984420863, "CELLCEPT": 0.8303694157974327, "CIMZIA": 0.5895135312844796, "CLOPIDOGREL": 0.8441047031440922, "COAPROVEL": 2.974625496828802, "COMIRNATY": 0.0774309893905118, "CYMBALTA": 1.1926352941663438, "DELAMANID": 6.9238733864126285, "DEXAMETHASONE": 1.0069383661259903, "DOCETAXEL": 0.7759806653406754, "DULOXETINE": 1.8186506596753973, "ELIQUIS": 0.4778884174008191, "ENBREL": 0.515242606307779, "ENTRESTO": 2.6413713536654835, "ESBRIET": 0.731543230335606, "EXFORGE": 2.4576294536832552, "EXJADE": 2.671426085233832, "FAMPYRA": 1.27845245563615, "FASLODEX": 0.5654493317646372, "FENTANYL": 0.606405620881178, "FIRDAPSE": 6.30595620601347, "GARDASIL": 0.3368871385991115, "HEPSERA": 4.202519375968437, "HIZENTRA": 1.4861067836560926, "HUMALOG": 1.1283303915181724, "HUMIRA": 1.669164369110655, "HYDROCORTISONE": 1.721774995993443, "IBRANCE": 2.882525104247077, "IBUPROFEN": 0.6944693000975508, "INCIVO": 0.8280301813670345, "INLYTA": 2.0215899822768413, "INSULIN": 1.3451423414036434, "IRBESARTAN": 1.3813476266207778, "JANUMET": 0.6006982456533705, "JANUVIA": 0.7563768793523535, "JARDIANCE": 1.2309073366774468, "KALETRA": 0.6917622602726587, "KEPPRA": 0.2334420234220137, "KEYTRUDA": 1.0492535751236345, "KYMRIAH": 3.0609553439728923, "LACOSAMIDE": 1.448885808587033, "LANTUS": 1.1874056225801228, "LEMTRADA": 0.9400639085330345, "LEVEMIR": 1.4011119444631177, "LEVOFLOXACIN": 0.5883605948100735, "LONSURF": 2.0863835900605374, "LYRICA": 1.1209506842334285, "MEKINIST": 1.0744753220092202, "METHOTREXATE": 0.9035468455362996, "MICARDISPLUS": 8.607866497485936, "NALOXONE": 14.426299324941953, "NEXAVAR": 0.3081249526200262, "NINLARO": 4.419237089920904, "NOT": 1.454726912044433, "NOVORAPID": 1.7233098570543188, "NOXAFIL": 2.945177435864435, "NUCALA": 14.9714765938723, "OLANZAPINE": 0.5400010770033046, "OMALIZUMAB": 0.672422786272331, "OPDIVO": 0.5150957481065085, "OPSUMIT": 3.307825617551852, "OZEMPIC": 5.431910715250264, "PANTOPRAZOLE": 2.9536083335544427, "PEGASYS": 3.145081888916673, "PEGINTERFERON": 0.6522200348044128, "PEGINTRON": 3.25666084427149, "PLAVIX": 0.3332628952435364, "RASILEZ": 2.0338621189914603, "REVATIO": 1.6823907358531305, "REVLIMID": 9.97575185905428, "RITUXIMAB": 0.5038631263787268, "RUBRACA": 5.754090876297713, "SAXENDA": 0.7082869790086929, "SILDENAFIL": 3.848338323989801, "SIMPONI": 0.2563164867337191, "SIRTURO": 18.92882110415466, "SOLIRIS": 1.5904585591004916, "SPIKEVAX": 0.0571755108325586, "SPINRAZA": 1.754250879180528, "SPIRONOLACTONE": 6.036230065080136, "SPRYCEL": 0.9113099076162936, "STELARA": 0.286349694188472, "STIVARGA": 0.7808858698146915, "SUBOXONE": 0.6620101875330023, "SUTENT": 1.8004781875134768, "TASIGNA": 0.6842439206707109, "TOZINAMERAN": 0.2749290869997812, "TRACLEER": 1.9449701405890227, "TRELEGY": 1.2779976021212986, "TRULICITY": 0.780738371837525, "VALSARTAN": 5.013963098025278, "VAXZEVRIA": 0.0290894358251479, "VELTASSA": 20.337569614335195, "VFEND": 1.6281100177578067, "VICTOZA": 2.0287766255000714, "VORICONAZOLE": 1.518217281149273, "VOTRIENT": 0.7283336607418589, "XALKORI": 1.6581734953991147, "XARELTO": 1.2781885659028105, "XELJANZ": 0.8118845305210116, "XOLAIR": 0.8239702100752118, "XTANDI": 1.2862546873711116, "XYREM": 5.348963562480917, "ZOSTAVAX": 1.51481033282954, "ZYPREXA": 1.0582685298810162, "null": 1.5625903540328745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1707.json
index f43ac409845..02db3115a6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1707.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1707.json
@@ -1 +1 @@
-{"COSENTYX": 6.3104677877748845, "CYTARABINE": 6.263185677137105, "ELIQUIS": 1.3212241969407357, "ESBRIET": 8.853499990347881, "FENTANYL": 3.4745002250455737, "IBRANCE": 4.821448054000725, "OPSUMIT": 4.975825637585127, "XELJANZ": 4.478265966807984}
\ No newline at end of file
+{"ABATACEPT": 0.786387255941891, "AFINITOR": 1.5534379598321484, "ALISKIREN": 4.4419691280030245, "AMINOSALICYLIC": 1.2813175856577497, "APIXABAN": 0.8579079395839808, "APROVEL": 2.9806674156757595, "ARANESP": 1.2815285457594885, "ARAVA": 0.5311307512584488, "ARIPIPRAZOLE": 1.7287586786382807, "BEDAQUILINE": 12.69000757519289, "BRILIQUE": 2.496154590736095, "BUMETANIDE": 4.28868497506558, "BUPRENORPHINE": 0.6959489926934312, "BYETTA": 0.6204405397012973, "CELECOXIB": 3.4054342737739822, "CELLCEPT": 0.6977329283848702, "CICLOSPORIN": 0.9605447696530054, "CLOPIDOGREL": 1.140494153276355, "COAPROVEL": 3.1496406793946554, "COMBIVIR": 1.3173083882976877, "COMIRNATY": 0.0501206043508647, "COSENTYX": 0.3913229081881362, "CYMBALTA": 0.1846903826239634, "DENOSUMAB": 6.328243870282749, "DEXAMETHASONE": 0.4321474185002666, "ELIQUIS": 0.486669297192333, "EMPAGLIFLOZIN": 6.998479867072879, "ENBREL": 0.4482683893533473, "ENTRESTO": 29.696279267929608, "ESBRIET": 1.4668989734360784, "EXFORGE": 4.283285087509094, "EXJADE": 3.0961584268525693, "FENTANYL": 0.4915822899657774, "FORSTEO": 1.0223071086956377, "FORXIGA": 1.6612697458173535, "HARVONI": 1.6104158106963586, "HUMALOG": 1.3800347693830244, "IBRANCE": 0.6366954664899295, "IBUPROFEN": 1.0227392931520798, "INLYTA": 2.862009334960658, "INSULIN": 0.8957848001963976, "IRBESARTAN": 6.435437934543185, "IVABRADINE": 29.645190118139265, "JAKAVI": 4.468510515495924, "JANUMET": 1.0535894791959168, "JANUVIA": 2.031461032161722, "JARDIANCE": 1.5698575459847188, "KEYTRUDA": 0.5220693142504262, "LANTUS": 0.8409616342022234, "LEVEMIR": 1.2582638928189218, "LEVOFLOXACIN": 0.970440296614326, "LYRICA": 1.4263610254572343, "MICARDIS": 12.64254691488062, "MULTAQ": 2.5343356117869105, "NEXAVAR": 1.4369416476230406, "NOT": 2.2236532236778337, "OPSUMIT": 1.115536572363505, "PEGASYS": 0.4958129235594307, "PEGINTERFERON": 0.996958042622366, "PLAVIX": 0.5645609570213677, "RASILEZ": 21.579952684977307, "SAMSCA": 33.017386769864274, "SOLIRIS": 1.124508124090588, "SPIKEVAX": 0.0347691939756987, "SPIRONOLACTONE": 16.08439894050272, "SUTENT": 1.447728156327, "TEKTURNA": 26.68296229833696, "TOZINAMERAN": 0.1151063254385838, "TRACLEER": 2.131973845850877, "VALSARTAN": 21.191445945582103, "VELTASSA": 99.879597427072, "VENETOCLAX": 6.749537019165823, "VFEND": 1.3381733933273166, "VOTRIENT": 1.6160159802724876, "XALKORI": 2.00065086666733, "XELJANZ": 0.3687621328187755, "XTANDI": 0.6925204197320602, "ZOSTAVAX": 0.3929388227484806, "ZYPREXA": 0.7959028362078256, "null": 1.803814148895733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1708.json
index 90df7ece454..edff9d6316c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1708.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1708.json
@@ -1 +1 @@
-{"ABATACEPT": 1.1221508956016053, "ACCOFIL": 3.674712311667832, "ACTOS": 1.5348117527050211, "ADALIMUMAB": 1.2848106169953362, "ADCIRCA": 1.3300536867440755, "ADEMPAS": 1.2168228509870644, "AJOVY": 2.0644040767882013, "AMBRISENTAN": 1.5458893668599147, "ANGIOX": 2.0049694070971675, "APIXABAN": 1.6870845402840196, "AVAMYS": 1.488140682693457, "AVANDAMET": 2.9880563191681166, "AVANDIA": 2.3082807721063108, "BEDAQUILINE": 1.327299754361711, "BENLYSTA": 1.0871814417012395, "BEXTRA": 1.050605623525884, "BONVIVA": 2.377434051531969, "BRILIQUE": 1.2066627424316256, "CHAMPIX": 1.644833605879491, "CIRCADIN": 1.095784523672441, "CLOPIDOGREL": 1.2379951833489962, "COMIRNATY": 2.0014027741041254, "COVID19": 1.362830835046632, "DAPAGLIFLOZIN": 1.6190071452412609, "DELAMANID": 1.0598384667830338, "DRONEDARONE": 2.1209288373673143, "DUPIXENT": 1.1573858067489011, "EPADERM": 7.247263622297539, "EPTIFIBATIDE": 3.4146354594030828, "ESBRIET": 1.1468359410517035, "EVUSHELD": 1.2790045008778568, "EXFORGE": 1.1134502510925828, "EXUBERA": 3.815785153627956, "FLEBOGAMMA": 3.2907454108623195, "FORSTEO": 1.3085955596652068, "GALAFOLD": 1.5878112905855015, "GARDASIL": 1.2849172180745383, "GILENYA": 1.013805265889438, "ICLUSIG": 1.0391531433464507, "INFERGEN": 1.341135279974165, "INTEGRILIN": 1.220296680287794, "IVABRADINE": 1.954825802725445, "KETEK": 1.144192425331584, "KIOVIG": 1.8873231358614715, "MICARDIS": 1.3765551990724698, "MIRCERA": 1.5978781819223191, "MOVYMIA": 1.0098295791084444, "NEULASTA": 1.479320029533377, "NILOTINIB": 1.0613531338434996, "NIVESTIM": 1.436712792012141, "OMALIZUMAB": 1.7047082071700328, "OPSUMIT": 1.6302916661876, "PEGASYS": 1.1413350424324795, "PLAVIX": 1.186571934937635, "PRASUGREL": 1.668429034865333, "PRIVIGEN": 1.5422653910413089, "RANEXA": 1.9090824002021736, "RANOLAZINE": 3.7942097068828007, "RAPISCAN": 2.6491982543369024, "REBIF": 1.031498059855007, "RELVAR": 1.0129296625325546, "REVATIO": 1.1058980092011133, "ROSIGLITAZONE": 1.2525648825493143, "SILDENAFIL": 1.3561623454740137, "SPIKEVAX": 1.7832530891460303, "TASIGNA": 1.5013089378347269, "TICAGRELOR": 1.2331300741084237, "TOZINAMERAN": 2.7957070698528304, "TRACLEER": 1.109829150079521, "TRAJENTA": 5.392860257938281, "ULTIBRO": 2.3672459175088583, "UMECLIDINIUM": 1.0624154008432083, "VARENICLINE": 1.6006704729308427, "VIAGRA": 1.2738147769892492, "XOLAIR": 1.387410262038974, "ZARZIO": 2.2365574421603203, "ZOMETA": 1.0638324958486145}
\ No newline at end of file
+{"SPIKEVAX": 45.89665018291424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1709.json
index 611cd94a615..3ec17a66598 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1709.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1709.json
@@ -1 +1 @@
-{"null": 1.34980289869398}
\ No newline at end of file
+{"ABILIFY": 0.9362593939209386, "ACLASTA": 16.221155519769955, "ADCIRCA": 4.480595491442218, "ADEMPAS": 5.4355459418869145, "AFINITOR": 0.5795280629281565, "AIMOVIG": 1.330227872585861, "AMBRISENTAN": 5.730729404650674, "AMINOSALICYLIC": 0.8638391679220995, "APROVEL": 3.124653917256459, "ARANESP": 0.8491672611601544, "ARIPIPRAZOLE": 1.4648857386516785, "ATRIPLA": 0.0684304659517763, "AUBAGIO": 0.9050737926044262, "AVAMYS": 0.8107716221689684, "AVANDIA": 0.7387044765242388, "BYDUREON": 1.396431993061959, "BYETTA": 0.6648263027004986, "CELLCEPT": 0.5326635932760047, "CHAMPIX": 0.5808283879254119, "CICLOSPORIN": 0.4069100241965168, "CIMZIA": 0.3241023706825956, "CLOPIDOGREL": 1.4415525688765165, "COMIRNATY": 0.6714293316152923, "CYMBALTA": 0.3706882263559018, "ELIQUIS": 1.8047493987390084, "ENBREL": 0.4241837330312765, "ENTRESTO": 5.915922562817076, "ESBRIET": 0.9344811704050056, "EXFORGE": 8.41077458933646, "FASENRA": 1.2852167265244674, "FENTANYL": 0.5661328077434614, "FORSTEO": 0.7461457575049109, "FORXIGA": 0.6969117126731894, "GARDASIL": 0.6727488868745207, "HUMALOG": 2.2890633085570515, "HUMIRA": 1.9658438698488512, "IBRANCE": 1.2237120097620509, "IBUPROFEN": 0.6515350703473411, "INLYTA": 4.108001222802455, "JANUMET": 0.9969479962462928, "JANUVIA": 0.9663929865420048, "JARDIANCE": 1.005869864200034, "KEYTRUDA": 0.8178401704036726, "KYMRIAH": 1.305491811240311, "KYPROLIS": 2.6691477146763685, "LANTUS": 1.4667705693762327, "LEFLUNOMIDE": 2.256924166313785, "LEVOFLOXACIN": 1.5541587765671094, "LYRICA": 3.528449076580614, "MEPOLIZUMAB": 2.3207513570810647, "MICARDIS": 4.162138188571201, "NEULASTA": 1.5819398847790151, "NEXAVAR": 0.5225413896885257, "OLANZAPINE": 0.3269489314088624, "OMALIZUMAB": 1.1159867190311232, "OPSUMIT": 1.1168840482722748, "PEGINTRON": 0.5258363098728475, "PEMBROLIZUMAB": 1.7603335243438472, "PLAVIX": 1.2266797286798217, "RASILEZ": 3.2204012504825035, "REVATIO": 1.9704619374615095, "SILDENAFIL": 2.811170325509885, "SIMPONI": 0.5048512736664229, "SOLIRIS": 1.064044826237239, "SPIKEVAX": 0.3538775657966715, "STELARA": 0.2606297430806852, "SUTENT": 2.329957169445774, "TELMISARTAN": 4.590611781376902, "TOVIAZ": 1.982646549811811, "TOZINAMERAN": 0.9698832475454346, "TRELEGY": 0.7737606167238542, "TRULICITY": 0.7106064939290166, "VALSARTAN": 5.105777875797806, "VAXZEVRIA": 0.4259504965043726, "VELTASSA": 3.57282827245338, "VIAGRA": 3.187241642929831, "VOTRIENT": 0.9305325190006376, "XELJANZ": 2.22553656850416, "XOLAIR": 0.7547628512108826, "XTANDI": 1.3442810453334104, "ZOSTAVAX": 6.037411237504069, "ZYPREXA": 0.3161585826475767, "null": 1.2337020559815148}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/171.json
index 7fa04fe60f8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/171.json
@@ -1 +1 @@
-{"BYDUREON": 41.74260263019695, "BYETTA": 220.0514409421921, "JANUMET": 118.27019031322354, "JANUVIA": 87.15553218523193, "VICTOZA": 46.48740408674061}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1710.json
index bd639a9175a..950d0c7d016 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1710.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1710.json
@@ -1 +1 @@
-{"CYTARABINE": 45.65588686346895}
\ No newline at end of file
+{"null": 0.6786973626991607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1711.json
index 2d30a8a399f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1711.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1711.json
@@ -1 +1 @@
-{"BRILIQUE": 44.17474893974636, "null": 3.2576093592163944}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1712.json
index 1b1f2b6e812..bbff6f9c9f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1712.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1712.json
@@ -1 +1 @@
-{"SIMPONI": 24.44434226161309, "STELARA": 49.95849854468705}
\ No newline at end of file
+{"ABACAVIR": 0.1052837124146995, "ABILIFY": 0.2409610637561313, "ACTOS": 0.6557186013850385, "ACTRAPID": 0.8161929446113911, "ADALIMUMAB": 0.0520406593484198, "ADCIRCA": 3.240273335753493, "ADEMPAS": 5.765103622474488, "AFINITOR": 0.8334540511818124, "AIMOVIG": 0.4182906248423816, "ALIMTA": 0.591293645132859, "AMBRISENTAN": 0.9508698111540184, "AMIKACIN": 0.7588861892947968, "AMINOSALICYLIC": 0.3893634118596529, "APIDRA": 0.2850050153107334, "APIXABAN": 0.2907171926836224, "APROVEL": 1.3140094624579954, "ARANESP": 0.213725552290873, "ARAVA": 0.0446724729499506, "ARIPIPRAZOLE": 0.3881924278250821, "ASPARAGINASE": 0.4481321878764283, "AUBAGIO": 0.1823377904398629, "AVASTIN": 0.8961508206244085, "AZILECT": 1.900009755737859, "BAVENCIO": 1.482044194986948, "BEDAQUILINE": 1.8214132962370837, "BELIMUMAB": 8.32675741692458, "BENLYSTA": 0.7341479738646648, "BENZODIAZEPINE": 1.189206681261327, "BETMIGA": 0.4981191474874141, "BEVACIZUMAB": 0.1735378115178547, "BONVIVA": 0.7929772244812965, "BRAFTOVI": 0.5544961644127789, "BREXPIPRAZOLE": 9.94446093546421, "BRIDION": 21.07040197758886, "BRILIQUE": 0.8636656337738426, "BRINTELLIX": 0.3067928159224546, "BUDESONIDE": 0.4223459940507489, "BUPIVACAINE": 3.939515681482246, "BUPRENORPHINE": 0.1384146743877222, "BYDUREON": 0.3133025226223042, "BYETTA": 0.6720559252045875, "CABOMETYX": 0.6146086098864559, "CAELYX": 0.7116744010659957, "CANCIDAS": 0.5426571790731575, "CAPECITABINE": 0.6668096396892587, "CARBIDOPA": 2.135864312684378, "CEFUROXIME": 4.679325223171978, "CELECOXIB": 0.8635561031624758, "CELLCEPT": 0.7089580577217915, "CHAMPIX": 0.4992332648543461, "CHLORHEXIDINE": 0.369253706902751, "CICLOSPORIN": 0.5819226809329757, "CIMZIA": 0.1137224537824804, "CLOPIDOGREL": 1.7409814823786955, "COAPROVEL": 2.270694147978263, "COMIRNATY": 0.6377385104596278, "COMTAN": 1.1700565928311968, "COSENTYX": 0.5121207048532481, "CUBICIN": 1.4132868764969442, "CYMBALTA": 0.7369853350003798, "CYTARABINE": 0.2632200031084053, "DACLATASVIR": 2.5938492580017813, "DAPAGLIFLOZIN": 4.758487161901079, "DARZALEX": 1.033589680618493, "DENOSUMAB": 1.12487383726352, "DEXAMETHASONE": 0.8940837004175817, "DEXMEDETOMIDINE": 2.4935854493243768, "DOCETAXEL": 0.3959386125957663, "DOXORUBICIN": 0.2593544430165536, "DULOXETINE": 0.2068844357969917, "EFIENT": 2.465125824048433, "ELIQUIS": 0.9459674557780434, "EMGALITY": 26.17659248993252, "EMPAGLIFLOZIN": 0.726780002224146, "ENALAPRIL": 4.593442206143159, "ENBREL": 0.1146226357598765, "ENOXAPARIN": 1.566234201303076, "ENTRESTO": 9.14833724784057, "ENTYVIO": 1.1718768471997014, "ESBRIET": 0.5104292265311015, "ESOMEPRAZOLE": 0.4716168916757908, "EVENITY": 0.7616657033834313, "EXELON": 2.655892552013212, "EXFORGE": 9.136985257030668, "EXJADE": 0.7152780599385594, "EYLEA": 0.1710288094956735, "FASENRA": 0.6852544353627957, "FASLODEX": 0.541570251216448, "FASTURTEC": 3.5456705675009723, "FEBUXOSTAT": 0.8846360584893083, "FENTANYL": 5.108855025025887, "FLEBOGAMMA": 3.4153555990514888, "FORSTEO": 1.7875106326317127, "FORXIGA": 1.7422093517365804, "GALVUS": 0.6049130644942908, "GARDASIL": 0.762955548652688, "GAZYVARO": 2.399377115575674, "GILENYA": 2.1194849036203207, "GLIVEC": 1.1438214225983812, "GLUCAGON": 3.306338907111413, "HERCEPTIN": 0.7142973656418237, "HIZENTRA": 0.5269371281919253, "HUMALOG": 0.4266636950468572, "HUMAN": 0.8622524618873882, "HUMIRA": 0.1160652675529815, "HYDROCHLOROTHIAZIDE": 2.1468993716663785, "HYDROCORTISONE": 0.2566372186215163, "IBRANCE": 0.3776204476921356, "IBUPROFEN": 0.9551816946433264, "INCIVO": 0.5647789523301764, "INLYTA": 0.625454353563761, "INSULIN": 0.1592091029920673, "IRBESARTAN": 2.2319750295435923, "ISOPHANE": 3.3394384321515225, "IVABRADINE": 6.564848971669989, "JAKAVI": 0.3590401626742565, "JANUMET": 0.2919320764460991, "JANUVIA": 0.4604995621984567, "JARDIANCE": 1.433138633032654, "JEVTANA": 3.4527533993486945, "KALETRA": 0.2329495487423288, "KEPPRA": 0.1998278398867931, "KEYTRUDA": 0.756041416129874, "KIOVIG": 1.9316804836051076, 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0.7417879639487842, "SHINGRIX": 0.4490181761191224, "SIFROL": 0.7687726623300964, "SILDENAFIL": 3.195365582724019, "SIMPONI": 0.2494226026491035, "SOLIRIS": 0.6032765484294319, "SOVALDI": 1.0058302627953482, "SPIKEVAX": 0.3050441091219205, "SPIRONOLACTONE": 1.931878750994912, "SPRYCEL": 0.1558465218653858, "STALEVO": 1.0353253270346068, "STELARA": 0.191021703322767, "STIVARGA": 0.1873524582584761, "SUBOXONE": 0.290577463972851, "SUFENTANIL": 4.480719009294605, "SUTENT": 0.7082295547511764, "TAGRISSO": 0.4278251217538786, "TAMIFLU": 1.4469074216066902, "TASIGNA": 0.2361974964416344, "TELMISARTAN": 3.355362847262481, "TICAGRELOR": 1.406172992925084, "TOBRAMYCIN": 2.054162149680281, "TOLVAPTAN": 12.857532436317255, "TORISEL": 1.6822334434296646, "TOVIAZ": 0.2415869387398616, "TOZINAMERAN": 0.387608709341244, "TRACLEER": 0.8288573770370489, "TRELEGY": 0.500588035259764, "TRULICITY": 0.898725231491605, "TWINRIX": 0.8674633439283341, "VALSARTAN": 14.609529575798229, "VAXZEVRIA": 0.3114034123449977, "VEKLURY": 1.9269128624853924, "VELTASSA": 0.4929099039592411, "VFEND": 0.7328010167263603, "VIAGRA": 2.1379563317221573, "VICTOZA": 0.4597286793671345, "VIMPAT": 0.6899228918012579, "VORICONAZOLE": 0.8667649408123344, "VOTRIENT": 0.1477788084186867, "XALKORI": 0.7997177379745268, "XARELTO": 0.8918881003396797, "XELJANZ": 0.2686154176647384, "XELODA": 0.4903245844184465, "XOLAIR": 1.6197673802447583, "XTANDI": 0.5753078831603823, "XYREM": 0.758431969462304, "ZIAGEN": 1.204246755638008, "ZOSTAVAX": 0.0551423344944847, "ZYPADHERA": 3.847048937370293, "ZYPREXA": 0.6628316395430839, "null": 2.32798072694596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1713.json
index ceb4ee59d8f..bfacb5de83f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1713.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1713.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 222.18240029466912, "null": 1.206942668319246}
\ No newline at end of file
+{"ACLASTA": 126.10292480836006, "ARAVA": 2.4242689196187177, "CIMZIA": 3.4930122630741085, "CYMBALTA": 4.172901740285552, "ELIQUIS": 2.530738728387959, "ESOMEPRAZOLE": 20.004370824312385, "JANUVIA": 6.157339770223707, "LEFLUNOMIDE": 22.25841646075108, "METHOTREXATE": 44.58546697680469, "MICARDIS": 10.49610307999825, "MYCOPHENOLATE": 16.133871072828164, "OFEV": 13.753948699635435, "RITUXIMAB": 116.0354773775987, "SILDENAFIL": 17.979550696670326, "VAXZEVRIA": 0.1953309669271236, "null": 0.6989810924368556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1714.json
index 28fa3da4df2..ee00e160720 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1714.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1714.json
@@ -1 +1 @@
-{"HEXYON": 3416.1109959636137}
\ No newline at end of file
+{"ACLASTA": 42.824865341921225, "ADALIMUMAB": 0.586130900114049, "ADCIRCA": 16.461796133706606, "AFINITOR": 9.091886459546034, "ANAKINRA": 8.730785394082448, "APIXABAN": 3.760262836685236, "ARAVA": 1.1768756185402114, "CAPECITABINE": 3.798594336727516, "CIMZIA": 1.277056997754623, "CLOPIDOGREL": 5.753947477084918, "COMIRNATY": 0.2092718412343783, "COSENTYX": 2.3686340864424222, "CYMBALTA": 2.455534974710062, "ENBREL": 1.4271991171542124, "ENTRESTO": 5.326675410249894, "ESOMEPRAZOLE": 6.813347562816841, "EXFORGE": 11.51735911103616, "EXJADE": 5.634849481211608, "JANUVIA": 3.739223912193413, "JARDIANCE": 1.850143210986684, "METHOTREXATE": 9.394511085629638, "OMALIZUMAB": 7.144085047970083, "PANTOPRAZOLE": 30.93822110470322, "RASILEZ": 18.59601325356756, "RITUXIMAB": 24.92227720653555, "TOZINAMERAN": 0.325064991754271, "VALSARTAN": 14.340032255750485, "XOLAIR": 2.381075546271854, "null": 1.202750927870932}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1715.json
index da97adc2ce4..8497cbd0796 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1715.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1715.json
@@ -1 +1 @@
-{"SUBOXONE": 116.90234484220994, "null": 1.605070692234245}
\ No newline at end of file
+{"ADALIMUMAB": 1.7336785222304518, "AFINITOR": 2.4993409714484405, "APIXABAN": 2.212541695096239, "ARAVA": 0.4129529832493868, "BEVACIZUMAB": 19.37512379610329, "CICLOSPORIN": 1.6088166508911212, "CIMZIA": 2.2015161041394777, "COMIRNATY": 0.441340763406856, "EXFORGE": 6.671122559105506, "INLYTA": 4.925452566458702, "METHOTREXATE": 12.979540630511588, "OMALIZUMAB": 6.992429422131104, "RASILEZ": 13.765266594494973, "RITUXIMAB": 32.81372107648853, "SILDENAFIL": 8.623255708745148, "SPIKEVAX": 0.3627930032288074, "SUTENT": 1.9502601519084104, "TOZINAMERAN": 0.3123288068761285, "VAXZEVRIA": 0.396200320396456, "XELJANZ": 1.111810642918786, "null": 1.052512810960183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1716.json
index 97a0d9828dd..98d31cfe0bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1716.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1716.json
@@ -1 +1 @@
-{"EXVIERA": 502.17815484810274, "NEXAVAR": 30.98701604734112, "OCALIVA": 872.0945336558773}
\ No newline at end of file
+{"ABILIFY": 0.6298630491512299, "ACLASTA": 10.003419313012758, "ADALIMUMAB": 0.0606008653950714, "AFINITOR": 0.9298529021729828, "AIMOVIG": 0.8176253272045326, "ALEMTUZUMAB": 1.6978837497261772, "ANAKINRA": 5.134298198342711, "APIXABAN": 1.1694187380906529, "APROVEL": 4.204710477006564, "ARANESP": 0.6678325964641972, "ARAVA": 0.5578988955111046, "AUBAGIO": 0.5582184878383445, "BENLYSTA": 1.075740481741789, "BRINTELLIX": 0.8019411805461062, "BUDESONIDE": 0.4032271039532501, "BUPIVACAINE": 1.4801297765316477, "BUPRENORPHINE": 0.9651476619428896, "CABOMETYX": 1.096936823508845, "CHAMPIX": 0.3337814245776754, "CICLOSPORIN": 0.3469227402305614, "CIMZIA": 0.9993427234570884, "CLOPIDOGREL": 1.2290584511863318, "COMIRNATY": 0.992338985196858, "COMTAN": 4.235586943060363, "COSENTYX": 0.4191165842375112, "CYMBALTA": 2.1483723183415058, "DEXAMETHASONE": 0.3216609936141928, "DOCETAXEL": 1.0349576370115017, "ELIQUIS": 0.759500388952813, "ENBREL": 1.9924812613170853, "ENTRESTO": 2.816196528686957, "ESBRIET": 1.2760780993005736, "EXFORGE": 15.446809599806995, "FENTANYL": 0.2887959184745851, "FORSTEO": 1.633766635126792, "FORXIGA": 0.9993820587177248, "GARDASIL": 0.3153941127162663, "HUMIRA": 0.7823704001398806, "HYDROCHLOROTHIAZIDE": 7.503337707575477, "IBRANCE": 0.3453631510194468, "IBUPROFEN": 0.6351685741194357, "IMATINIB": 4.039463015024875, "INFLECTRA": 22.13212700151066, "INFLIXIMAB": 13.07389755788197, "INLYTA": 2.1288792481236265, "IRBESARTAN": 1.9478938201174, "JANUMET": 0.5448321461837959, "JANUVIA": 1.0999168498802063, "JARDIANCE": 0.3081751210802236, "KEPPRA": 0.234552233177346, "KEYTRUDA": 0.2778965200128279, "LANTUS": 0.2458739874988177, "LENVIMA": 1.5238823235609729, "MEPOLIZUMAB": 1.238237722416652, "METHOTREXATE": 2.2201230547442217, "MICARDIS": 6.198130716275901, "OFEV": 0.98624322684475, "OLANZAPINE": 0.731680325236251, "OMALIZUMAB": 0.6098859316633827, "OPSUMIT": 0.3257093789071528, "PEGASYS": 0.194968479467419, "PEGINTRON": 0.287371227401701, "PLAVIX": 0.3069862512986752, "RASILEZ": 14.248234425507968, "RITUXIMAB": 12.247653025128942, "SHINGRIX": 0.3714691274481062, "SIMPONI": 1.2469160780849038, "SPIKEVAX": 0.6693222505833382, "SUBOXONE": 0.5216757289696891, "SUTENT": 2.02124417501229, "TASIGNA": 0.6874980658501411, "TELMISARTAN": 3.6105456277226993, "TOZINAMERAN": 0.6649436824220603, "VALSARTAN": 10.071686878996095, "VAXZEVRIA": 0.4272723117846901, "VIAGRA": 0.5010361117091031, "VOTRIENT": 0.6188727374747107, "XELJANZ": 0.3679582057265716, "XOLAIR": 0.7882828490151165, "XTANDI": 1.0102464523664714, "ZOSTAVAX": 0.3882079217550401, "ZYPREXA": 0.5596104117870593, "null": 1.3878364429772532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1717.json
index 011503b6a2c..c7c5f950835 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1717.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1717.json
@@ -1 +1 @@
-{"null": 1.9063802394215228}
\ No newline at end of file
+{"COMIRNATY": 0.3917714107962518, "FENTANYL": 8.623840001680797, "MIDAZOLAM": 23.64713536662452, "null": 4.966906574802775}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1718.json
index 2c662fae98b..c122599dc39 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1718.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1718.json
@@ -1 +1 @@
-{"COMIRNATY": 3.6256722447224736, "COVID19": 2.105023455263645, "SPIKEVAX": 1.600563483874539, "TOZINAMERAN": 2.8024288976666707}
\ No newline at end of file
+{"ALISKIREN": 75.99099588576873, "APROVEL": 4.671685687153838, "COAPROVEL": 6.258516678420726, "COMIRNATY": 0.0493009240120012, "CYMBALTA": 0.9727036106211432, "ELIQUIS": 0.4114140030110607, "EXFORGE": 77.81979819753562, "FORXIGA": 1.4625023022245418, "IRBESARTAN": 10.563412562667695, "MICARDIS": 14.110070755920894, "RASILEZ": 110.24126918567978, "TEKTURNA": 143.43369787291007, "TELMISARTAN": 42.25598979425666, "VALSARTAN": 39.216790828152185, "null": 3.7539131168799007}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1719.json
index 9f058183267..165a7ff4296 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1719.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1719.json
@@ -1 +1 @@
-{"BAVENCIO": 1.399774867511963, "COMIRNATY": 2.2684483213341604, "COMPOUND": 11.469155183502448, "COVID19": 5.88157733035379, "FLEBOGAMMA": 7.4501868887181635, "FLUCELVAX": 1.0550050151477333, "GAZYVARO": 1.3658848152889662, "JCOVDEN": 2.671156983359535, "KANJINTI": 5.29118140427494, "KESIMPTA": 1.894060690435487, "KIOVIG": 4.4110875423212565, "MEKINIST": 1.209051279309526, "PERJETA": 1.8503442769811012, "PRIVIGEN": 3.014999674561454, "PROVENGE": 1.6229022504402848, "RIXATHON": 1.6203774959262518, "SHINGRIX": 1.750399085940577, "SPIKEVAX": 3.94496462774514, "TAFINLAR": 1.0354321343734123, "TOZINAMERAN": 1.216913232308181, "VAXZEVRIA": 5.067167443898866, "ZIAGEN": 1.438875145746639}
\ No newline at end of file
+{"ABASAGLAR": 0.5981412600397066, "ABATACEPT": 0.0510711041223181, "ABILIFY": 0.4905747019110792, "ACE": 3.373135726292182, "ACLASTA": 1.646697907653041, "ACLIDINIUM": 0.3209810309150643, "ACTOS": 0.8506852388123851, "ADALIMUMAB": 0.1582546254752027, "ADEMPAS": 0.4159082228093855, "ADENURIC": 0.4467494275395151, "AERIUS": 0.7115781530127216, "AFINITOR": 2.039883353706457, "AGALSIDASE": 6.429215857773958, "AIMOVIG": 1.2924026589389443, "ALEMTUZUMAB": 0.3239818229296311, "ALIMTA": 0.1922125650968742, "ALISKIREN": 6.840133936477819, "AMINOSALICYLIC": 0.1231504506094698, "ANAKINRA": 0.9777890416400612, "ANORO": 0.3022713778799916, "ANTIHYPERTENSIVES": 5.198957911130397, "APIDRA": 0.5817229038010029, "APIXABAN": 0.2755083889811018, "APROVEL": 4.769438576719344, "ARANESP": 0.5794029906843522, "ARAVA": 0.2872231889107472, "ARIPIPRAZOLE": 0.2637705116685289, "ASPARAGINASE": 0.4525900624747965, "ATRIPLA": 0.0094632863126902, "AUBAGIO": 1.4454234250926188, "AVAMYS": 0.5542586921015505, 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0.594904768075538, "RYBELSUS": 0.5871175312097366, "SAXENDA": 0.5598368371455065, "SHINGRIX": 0.3467837463182423, "SIFROL": 0.6448113463916516, "SILDENAFIL": 1.0401238115884732, "SIMPONI": 0.610302202044361, "SOLIRIS": 1.168109095735735, "SOMAVERT": 2.6867497856468776, "SORAFENIB": 0.8775446273422333, "SOVALDI": 0.4813650316530928, "SPIKEVAX": 0.4961241247402345, "SPIRONOLACTONE": 1.0003465281006414, "SPRYCEL": 0.4201434721000828, "STALEVO": 0.8340747413813503, "STELARA": 0.3034754222392178, "STIVARGA": 2.5831125861089967, "SUBOXONE": 0.4216523128056422, "SUTENT": 3.849954427133298, "TACROLIMUS": 0.7535586571821676, "TADALAFIL": 2.6807247592811034, "TAGRISSO": 0.2676740654623733, "TAMIFLU": 0.2602166115306755, "TASIGNA": 0.415753071335163, "TEKTURNA": 8.850686979422518, "TELMISARTAN": 3.3168304021918025, "TERIFLUNOMIDE": 1.228312584520684, "TICAGRELOR": 0.6275087795351575, "TORISEL": 0.615376465959982, "TOUJEO": 0.5905977347221525, "TOVIAZ": 0.8790457528847695, "TOZINAMERAN": 0.9047093510376888, "TRACLEER": 0.213920328183402, "TRELEGY": 0.4289880803392986, "TREMFYA": 0.2437894038036668, "TRULICITY": 1.3492890205907155, "TRUVADA": 0.016255784647969, "TWINRIX": 0.2543964810171634, "TWYNSTA": 2.8810042163462177, "VALSARTAN": 5.348712396639927, "VAXZEVRIA": 0.4991675136447767, "VELTASSA": 0.669008881635812, "VFEND": 0.2215944144427799, "VIAGRA": 1.386078174822416, "VICTOZA": 0.6883956454108734, "VIMPAT": 0.2328424184931951, "VOTRIENT": 3.370858915374193, "XARELTO": 0.3729370192076364, "XELJANZ": 0.9691302739529624, "XELODA": 0.4457261288200076, "XOLAIR": 1.9431232976869213, "XTANDI": 1.659675726584024, "XYREM": 2.878320315465713, "ZEJULA": 4.515520300608007, "ZOSTAVAX": 0.3664750328096909, "ZYPADHERA": 3.859726599169259, "ZYPREXA": 0.539720785995824, "null": 1.445890453871404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/172.json
index 92fe2943495..b1f1e34550f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/172.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0343569162886947, "null": 1.5509588587280032}
\ No newline at end of file
+{"COSENTYX": 12.093647424940576, "KALETRA": 29.811796886167265, "null": 0.8938569660858858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1720.json
index 21f82d4d9ce..ae04056dec6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1720.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1720.json
@@ -1 +1 @@
-{"CICLOSPORIN": 43.03389933184699}
\ No newline at end of file
+{"AIMOVIG": 9.191573145381064, "COMIRNATY": 0.5785025676415327, "ELIQUIS": 1.897834604927684, "ERENUMAB": 88.48518702527767, "SPIKEVAX": 0.456353177184697, "VAXZEVRIA": 4.349012830770303, "null": 0.5425368151283191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1721.json
index c795c3af0db..ff70ed8fffc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1721.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1721.json
@@ -1 +1 @@
-{"null": 2.6900865223538863}
\ No newline at end of file
+{"VAXZEVRIA": 2.374773925719511, "null": 0.5033462095138237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1722.json
index 0be2907deaa..7cbc0081738 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1722.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1722.json
@@ -1 +1 @@
-{"BUSULFAN": 94.02116822976492, "CYTARABINE": 35.535503929416336}
\ No newline at end of file
+{"null": 2.990785607380725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1723.json
index 49538433b35..8dc465266d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1723.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1723.json
@@ -1 +1 @@
-{"VFEND": 240.6367787300532, "VIAGRA": 193.30419561825585, "VORICONAZOLE": 127.34994018849072}
\ No newline at end of file
+{"null": 1.2792279924443763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1724.json
index d0b7fe24efd..c4e645a6357 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1724.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1724.json
@@ -1 +1 @@
-{"null": 11.146063429893132}
\ No newline at end of file
+{"null": 1.7892381611854835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1725.json
index b0bf9c86f5f..10a34555948 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1725.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1725.json
@@ -1 +1 @@
-{"ABILIFY": 1.0466935372654134, "ANORO": 5.441184170511055, "AVAMYS": 2.404065173054178, "BRILIQUE": 2.014341742189898, "BUPRENORPHINE": 9.086827072912566, "COMTAN": 6.046088126811237, "ESBRIET": 1.206183586122025, "EXFORGE": 2.09083577988157, "FASENRA": 1.057624434352933, "FIRDAPSE": 2.9498612247891223, "GLYCOPYRRONIUM": 12.690589165002294, "IBRANCE": 2.0301566157253434, "INCRUSE": 16.182369495033704, "IRBESARTAN": 2.3272563654825715, "JANUMET": 1.5354167129076353, "MEPOLIZUMAB": 5.197176735522355, "MICARDIS": 1.1079927092592197, "NUCALA": 2.7782184905837437, "OMALIZUMAB": 3.289418995894397, "OXYBUTYNIN": 4.180684478378654, "PANTOPRAZOLE": 2.005047878103515, "PREVENAR": 3.440455028525097, "RELVAR": 2.25901327344108, "ROTATEQ": 5.406119733405012, "SPINRAZA": 6.074218162951523, "STALEVO": 5.741959648652567, "SYNAGIS": 2.8745433807955103, "TOVIAZ": 1.3384815232466512, "TRELEGY": 26.503436948744728, "XELJANZ": 1.287095021342138, "XOLAIR": 2.697133503589303, "XTANDI": 3.0075903289379786, "null": 3.126424088601889}
\ No newline at end of file
+{"COMIRNATY": 0.5552461789524855, "null": 1.023860288544021}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1726.json
index 02840c031ba..d6ad036f816 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1726.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1726.json
@@ -1 +1 @@
-{"FORSTEO": 2.808218466459006, "NUCALA": 1.9324777758532083, "OMALIZUMAB": 2.9024203933604884, "XOLAIR": 2.782763696931359, "null": 3.0760840808994314}
\ No newline at end of file
+{"ACLASTA": 128.3011620091081, "ANAKINRA": 14.346390257039696, "ARAVA": 2.373525014804533, "CLOPIDOGREL": 7.434333747441004, "ELIQUIS": 2.1715160619404137, "ENTRESTO": 5.338238989462096, "ESOMEPRAZOLE": 20.35152478039202, "METHOTREXATE": 39.55726428846146, "MICARDIS": 19.630022783616592, "RITUXIMAB": 148.20638169563844, "SILDENAFIL": 18.291105997256984, "VAXZEVRIA": 0.1225866059754114, "null": 0.6171499709164759}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1727.json
index 0ff56b96d14..1fa0ff8b45c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1727.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1727.json
@@ -1 +1 @@
-{"BYETTA": 10.526791795499086, "HARVONI": 17.663420147562075, "JANUMET": 8.909702863446293, "JANUVIA": 9.627784652677205, "NEXAVAR": 4.56239475175476, "VICTOZA": 23.73977713867856}
\ No newline at end of file
+{"ADCIRCA": 18.167031387000517, "AFINITOR": 1.2581792543149846, "ANAKINRA": 6.343514605729983, "ARAVA": 0.1891202901694483, "BRIDION": 6.361915992810059, "BUMETANIDE": 20.205542814212677, "CAPECITABINE": 3.3390626975482824, "CLOPIDOGREL": 2.1591701468733207, "COMIRNATY": 0.1684250189881063, "CYMBALTA": 0.8332143884218628, "DASATINIB": 20.77244648872229, "ELIQUIS": 0.5796359923639903, "ENTRESTO": 47.24903908371801, "EXFORGE": 5.5890487212959865, "FENTANYL": 10.364195736363117, "INFLIXIMAB": 19.546202951258667, "IVABRADINE": 83.14769727377978, "JANUVIA": 3.072645256243865, "JARDIANCE": 1.8659021360586767, "KEPPRA": 1.5731998454262104, "KYMRIAH": 5.956464603966593, "MEPOLIZUMAB": 2.068092260798547, "MIDAZOLAM": 9.453365615780044, "OPSUMIT": 1.719199088848933, "PANTOPRAZOLE": 9.155965614204984, "PROPRANOLOL": 13.24687798513316, "RASILEZ": 6.780974278636445, "TOZINAMERAN": 0.2306676882789158, "null": 1.8229296126251693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1728.json
index dc435071fde..54b41fb930b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1728.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1728.json
@@ -1 +1 @@
-{"ABRAXANE": 15.685979048365702, "AFINITOR": 3.3657958534526253, "BYETTA": 8.09432931521846, "CABOMETYX": 6.353758020564221, "CELLCEPT": 4.221117363111109, "CICLOSPORIN": 1.918635842981572, "COMBIVIR": 6.734371444184069, "ENTYVIO": 2.340651189596253, "IRINOTECAN": 10.23539343616353, "JANUMET": 7.839497423433308, "JANUVIA": 6.2382858210847045, "JARDIANCE": 1.2384617875052213, "KEYTRUDA": 12.698949945278873, "LENVIMA": 31.238836287333168, "MEKINIST": 4.815352855375657, "NEXAVAR": 10.43012482591973, "OPDIVO": 9.07120859395352, "PEMBROLIZUMAB": 3.661618814149698, "SAXENDA": 3.1651063863210624, "SOLIRIS": 2.1464272869291823, "STELARA": 1.8825127263475503, "STIVARGA": 7.163498903841889, "SUTENT": 1.5020686208528435}
\ No newline at end of file
+{"ABATACEPT": 1.924180942398584, "ACLASTA": 12.809967703396197, "ADALIMUMAB": 0.9240230189945764, "AFINITOR": 9.6110931999429, "AIMOVIG": 0.3882802509018722, "APIXABAN": 0.6411479644932723, "ARAVA": 0.3664211880100619, "BAVENCIO": 7.94399100849343, "BETMIGA": 7.600927591689569, "CABOMETYX": 1.0007565090209225, "CELECOXIB": 3.245382052519473, "CHLORHEXIDINE": 1.4106478871293815, "CICLOSPORIN": 0.2759030057049551, "CIMZIA": 1.0632961853714342, "CLOPIDOGREL": 1.6999842092589903, "COMIRNATY": 0.2710330217238941, "COSENTYX": 3.157968965602352, "CYMBALTA": 4.3114041180803095, "DEXAMETHASONE": 0.8691430073183019, "DULOXETINE": 2.0221250672520936, "ELIQUIS": 0.637242857178703, "ENBREL": 0.5671422649574562, "ENTRESTO": 3.821362865648435, "ERLEADA": 2.989071122070139, "ESOMEPRAZOLE": 4.593030952004533, "EVEROLIMUS": 4.777221955175985, "EXFORGE": 25.6653199803015, "EXJADE": 1.2220147324911448, "FENTANYL": 1.446041011348156, "FLEBOGAMMA": 4.886957626310301, "FORSTEO": 0.8065308521055156, "IBRANCE": 0.2850000458851656, "ILARIS": 32.642047386628555, "INLYTA": 1.8649914584271836, "INSULIN": 2.191628588623225, "IRBESARTAN": 5.592911012115222, "JAKAVI": 0.8091290760188417, "KEYTRUDA": 0.3009495895318748, "KYMRIAH": 1.6658303454948613, "LANTUS": 0.2469382497552845, "LEFLUNOMIDE": 4.1449850539173525, "LUTETIUM": 19.2508836720835, "LYRICA": 0.7170174900081985, "MEPOLIZUMAB": 0.7045343021237309, "METFORMIN": 12.905443169736596, "METHOTREXATE": 7.960071148518089, "MICARDIS": 4.523947690889748, "NEXAVAR": 1.8642238195244143, "OFEV": 0.9967503978725925, "OMALIZUMAB": 31.536616140820204, "ORENCIA": 14.795038480220551, "PANTOPRAZOLE": 14.120089639178842, "PAZOPANIB": 4.562947080318598, "PLAVIX": 0.288690031046039, "PRIVIGEN": 1.9610010600959185, "RASILEZ": 24.80130467433001, "RITUXIMAB": 19.99049856084969, "SHINGRIX": 0.4251216334491274, "SILDENAFIL": 2.83123030975194, "SPIKEVAX": 0.054174791332471, "STELARA": 0.2972313364897826, "STIVARGA": 1.5650126891894771, "SUTENT": 1.218644625680481, "TELMISARTAN": 3.729874266038971, "TOZINAMERAN": 0.2910438626973242, "VALSARTAN": 3.873286406434437, "VAXZEVRIA": 0.0840025861762363, "VOTRIENT": 1.2344367386001371, "XELJANZ": 0.8170813058115944, "XOLAIR": 2.830253663699947, "XTANDI": 0.6599725981954345, "ZOSTAVAX": 0.7099040244584386, "null": 1.4354980543060376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1729.json
index 550f0e3664a..52798a10daa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1729.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1729.json
@@ -1 +1 @@
-{"BYETTA": 18.52911236636841, "KEYTRUDA": 4.793585514195206, "null": 1.0732725499666034}
\ No newline at end of file
+{"ARANESP": 25.08298137849933, "SOLIRIS": 118.65662604723413, "null": 0.8011494856688806}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/173.json
index fbcd1f05691..dfb94ca9f6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/173.json
@@ -1 +1 @@
-{"null": 2.5360437193186063}
\ No newline at end of file
+{"SOMAVERT": 1167.8586757180838, "null": 4.945559032232862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1730.json
index 30384164012..5c9df36d017 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1730.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1730.json
@@ -1 +1 @@
-{"BUDESONIDE": 4.216534438585718, "CICLOSPORIN": 3.717529831292673, "ENTYVIO": 31.794912798096867, "HUMIRA": 11.96702018756216, "KEYTRUDA": 59.75649593900794, "OPDIVO": 18.55649613057516, "PEMBROLIZUMAB": 16.05668030423402, "STELARA": 7.421446259978675}
\ No newline at end of file
+{"AZATHIOPRINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1731.json
index d33ec3b540d..ccc4d1ac9d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1731.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1731.json
@@ -1 +1 @@
-{"AUBAGIO": 2.411383413191732, "BENLYSTA": 2.596454991117624, "BYDUREON": 8.94217434109356, "BYETTA": 26.493886455999068, "CIMZIA": 1.308896943808807, "CYMBALTA": 2.531439930252384, "DULOXETINE": 6.616498558214437, "ENTYVIO": 2.7440029379404693, "EVISTA": 6.18790886593593, "EXJADE": 4.240231982325946, "FORSTEO": 1.5562975550109952, "HIZENTRA": 6.668405516410621, "HUMIRA": 2.6857466399380754, "IBRANCE": 1.1691124582112715, "INSULIN": 2.0347121735245906, "JANUMET": 30.071097306961622, "JANUVIA": 19.566339869656584, "LANTUS": 1.7932081131030737, "OPSUMIT": 3.4760526481695693, "PEGINTRON": 2.655286764176956, "PLAVIX": 1.0383355588382783, "SAXENDA": 29.167290568733552, "SIMPONI": 2.8835840144335765, "STELARA": 5.7961412092404005, "TRACLEER": 3.436167055841836, "TRELEGY": 2.3292011040556155, "TREMFYA": 4.808186939785323, "VICTOZA": 6.528368245776929, "VOTRIENT": 2.0929049844502297, "ZOSTAVAX": 6.500390445283776, "null": 1.1446457547899649}
\ No newline at end of file
+{"ABILIFY": 1363.272487165775, "ARIPIPRAZOLE": 57.95968182027041, "null": 0.1136966213021131}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1732.json
index a24f15a41f3..4a5930d20ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1732.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1732.json
@@ -1 +1 @@
-{"AFINITOR": 1.4825678844105514, "AUBAGIO": 1.2720584850728949, "AVASTIN": 1.259648312408434, "BUSULFAN": 1.5161674182736096, "BYDUREON": 1.5932811206529085, "BYETTA": 7.171918699960036, "CABOMETYX": 2.289180729189178, "CELLCEPT": 1.6333519199234587, "CLOPIDOGREL": 1.071474230214443, "COMBIVIR": 4.319460760248536, "CYTARABINE": 2.444960130502968, "DEXAMETHASONE": 1.6153593316443875, "EFIENT": 8.970764776553374, "EXJADE": 2.362144882383937, "FORSTEO": 1.135914174597878, "FORXIGA": 1.406546320689103, "IBUPROFEN": 1.0725033629037617, "INLYTA": 2.0777545468485665, "ISENTRESS": 5.510024181886348, "JANUMET": 5.362700387844019, "JANUVIA": 3.917782039632061, "KEYTRUDA": 5.822201377567525, "LEMTRADA": 5.913156135792227, "LENVIMA": 23.69378658833244, "LYRICA": 1.1684475395048115, "MICARDIS": 1.7462716523484674, "NEXAVAR": 2.4764229365856085, "NORVIR": 6.794073087952374, "OFEV": 1.8388622247136672, "OPDIVO": 2.9151497116995624, "OPSUMIT": 1.4349974434331487, "OZEMPIC": 11.39062469689137, "PEGASYS": 1.514441465770046, "PEGINTRON": 1.5629658916769773, "PEMBROLIZUMAB": 2.176121024718049, "REVESTIVE": 36.47029122276876, "REYATAZ": 12.233773176654251, "ROACTEMRA": 2.1185356113089937, "RYBELSUS": 7.920465092458788, "SAXENDA": 33.63457735568049, "SIMPONI": 1.5322477168445965, "SOLIRIS": 4.317567596492592, "STELARA": 1.4931591068272283, "STIVARGA": 3.506593248066369, "SUTENT": 3.4512727976846582, "TASIGNA": 1.746333492042437, "TRACLEER": 1.8306838527559928, "TRULICITY": 3.498049201045728, "VFEND": 4.997080445856948, "VICTOZA": 8.163008772306082, "VOTRIENT": 1.0609874471938572, "ZYPREXA": 1.724009285352653, "null": 1.018966199577783}
\ No newline at end of file
+{"null": 1.5628611817689189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1733.json
index 870b173432a..1be6961cd1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1733.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1733.json
@@ -1 +1 @@
-{"ANAKINRA": 8.412853877057474, "AVASTIN": 3.767793974396821, "BYETTA": 8.964901186281852, "CLOPIDOGREL": 2.097446672951597, "CYTARABINE": 3.176263728869182, "INCIVO": 6.322766785277191, "JANUVIA": 2.938001639445291, "JARDIANCE": 1.3702316044596972, "KAFTRIO": 11.637961427310794, "KEYTRUDA": 5.795574039374032, "LEMTRADA": 11.907234357870486, "LENVIMA": 20.976946497177167, "NEXAVAR": 3.260053774123534, "PEGASYS": 1.9110417141459857, "PEGINTRON": 1.4152096997303314, "PLAVIX": 1.5134491679596247, "REYATAZ": 17.147099570275603, "ROACTEMRA": 2.73903000671301, "SAXENDA": 16.040874763471027, "SOLIRIS": 2.0962157568382405, "STELARA": 1.908931645120108, "SUTENT": 1.8069874636613952, "TASIGNA": 2.670496382121365, "TRULICITY": 3.1154684804962995, "VFEND": 5.6911204908364255, "VICTOZA": 13.510955063997743}
\ No newline at end of file
+{"ABILIFY": 11.711487498815028, "ARIPIPRAZOLE": 15.30190465051583, "BRINTELLIX": 10.897428039078886, "CARIPRAZINE": 136.79080639331687, "COMIRNATY": 0.0427810177501931, "CYMBALTA": 1.891164998458935, "INVEGA": 141.64254342732255, "LATUDA": 26.334610390357557, "MELATONIN": 16.03077160976915, "OLANZAPINE": 29.07150416472916, "RISPERIDONE": 22.948509763138265, "ZYPREXA": 21.685241915982584, "null": 2.5586520515592817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1734.json
index 0c43d3acbc9..47c7bf06b18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1734.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1734.json
@@ -1 +1 @@
-{"BEDAQUILINE": 47.86832925553114, "BYETTA": 39.24058079973306, "CELLCEPT": 6.386970314702105, "JANUMET": 24.61986531921088, "JANUVIA": 14.426656911212511, "null": 2.6672259111164243}
\ No newline at end of file
+{"HUMALOG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1735.json
index c7a5cabe46b..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1735.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1735.json
@@ -1 +1 @@
-{"SUTENT": 5.337919942627307}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1736.json
index 0eff958903d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1736.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1736.json
@@ -1 +1 @@
-{"ACLIDINIUM": 24.42525250159686, "ADCIRCA": 2.6940427654210564, "AFINITOR": 1.2407268677779997, "ANORO": 1.4042559523675244, "APIDRA": 1.2653154277747505, "APROVEL": 1.4708715824769936, "APTIVUS": 41.75148063711991, "ATAZANAVIR": 3.728836463302295, "BENLYSTA": 1.23896019754815, "BOSUTINIB": 7.108120340755055, "BYDUREON": 4.954964630147122, "BYETTA": 18.790855081611348, "CELECOXIB": 8.545022484868394, "CELLCEPT": 1.121072695080952, "CINACALCET": 8.787950398606334, "COMBIVIR": 1.3848575882334349, "DEXAMETHASONE": 1.056957285460382, "ESBRIET": 1.5513369163018795, "EVISTA": 1.6886842619935314, "EXFORGE": 3.0221227854450223, "EXJADE": 4.806846350703177, "EXVIERA": 2.8851364449251573, "FAMPYRA": 1.553356015554062, "FORSTEO": 3.3551089132951804, "GALVUS": 7.085289593069954, "HUMALOG": 1.296713582638924, "IBRANCE": 1.1156248553279549, "ISENTRESS": 5.1784553714505845, "JAKAVI": 1.903835578950969, "JANUMET": 12.19815211755869, "JANUVIA": 10.612519155420008, "KAFTRIO": 3.912263863510308, "KALETRA": 1.4014975155366427, "KIVEXA": 7.463124612674903, "LEVEMIR": 1.9323009878534736, "METHOTREXATE": 2.0930801673690014, "MICARDIS": 2.0002320010327863, "NORVIR": 9.640760788165757, "NPLATE": 1.4039258387797509, "OCALIVA": 3.0490047592324063, "OCTREOTIDE": 19.996518143655745, "OMALIZUMAB": 1.5175678054974238, "ONGLYZA": 3.501837010707145, "OPSUMIT": 1.1533713752849597, "OZEMPIC": 5.811138751761907, "PANTOPRAZOLE": 2.0393527855039646, "PEGASYS": 1.8355933127403212, "REMICADE": 2.5652755038623924, "REYATAZ": 29.8601114088961, "RYBELSUS": 10.996824415257352, "SAXENDA": 49.67993708648, "SIMPONI": 1.5312383673823562, "SOLIRIS": 6.01150075147884, "SOVALDI": 1.7599041867614893, "SPINRAZA": 1.480374258171984, "STELARA": 2.045257067996521, "SUBOXONE": 1.2864724443746225, "SUTENT": 1.259587417717417, "TASIGNA": 1.851214086076264, "TRACLEER": 2.0824844979410857, "TRULICITY": 6.044942800254252, "VELTASSA": 1.5307346016402, "VFEND": 1.3049680818287412, "VICTOZA": 17.57159315246899, "XELJANZ": 1.3743111786516091, "ZOMETA": 5.003313386098775, "ZYPREXA": 2.2814739803491992, "null": 1.2890922912844136}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1737.json
index 1d2f18dbecf..78573193fc9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1737.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1737.json
@@ -1 +1 @@
-{"null": 1.1861990206188366}
\ No newline at end of file
+{"null": 1.820387970837421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1738.json
index a5a7eccc13a..fc770db1cfb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1738.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1738.json
@@ -1 +1 @@
-{"ADENURIC": 5.40001376007055, "AERIUS": 3.666054413651656, "ALIMTA": 2.7498367473777408, "ALOXI": 19.729984872759196, "AMIKACIN": 1.9886208205663296, "APROVEL": 2.1787190983906277, "ARIXTRA": 5.817716679103597, "ASPARAGINASE": 4.655123164463696, "ATAZANAVIR": 2.3912400738544197, "AVASTIN": 2.1616983788964, "AZATHIOPRINE": 1.073070185495197, "BRAFTOVI": 2.4387481631134635, "BRILIQUE": 2.148843069253679, "BRIVIACT": 1.7793704193099762, "CAELYX": 1.421342713670884, "CANCIDAS": 17.967073155052127, "CANNABIDIOL": 4.561354074717738, "CASPOFUNGIN": 3.527023443307823, "CELLCEPT": 2.83963586216232, "CICLOSPORIN": 1.3895683959825111, "CLOPIDOGREL": 1.12532544324964, "COAPROVEL": 2.702334436723396, "COMBIVIR": 2.945362665321805, "COTELLIC": 11.8751675120925, "CUBICIN": 2.4078672848134346, "CYTARABINE": 1.0685051672038357, "DARZALEX": 1.151604926874182, "EFAVIRENZ": 2.209900875586501, "ELIQUIS": 1.1279542569407413, "EMEND": 4.9458198199253, "EMTRICITABINE": 2.709380811195733, "ENOXAPARIN": 1.370499869818883, "EPIVIR": 2.3943419227750757, "ESOMEPRAZOLE": 5.365756542957679, "EUCREAS": 2.4232999562892514, "FUZEON": 30.52912981358692, "GALVUS": 5.328536015386185, "GANCICLOVIR": 2.407620749303092, "GLIVEC": 2.728410474128639, "IBUPROFEN": 1.7308370993675832, "ICLUSIG": 1.037919814185937, "IMBRUVICA": 4.466737592476926, "INSULATARD": 5.684249792751863, "IPILIMUMAB": 1.1337674161217224, "IRBESARTAN": 3.539711827522515, "ISENTRESS": 2.490338253774196, "ISOPHANE": 10.343487952075716, "JANUMET": 1.0967945414600506, "JANUVIA": 1.2054402121441496, "KAFTRIO": 1.4757189827442194, "KALETRA": 6.010480822929652, "KEPPRA": 5.182416925331632, "KEYTRUDA": 1.3936912668871644, "KISQALI": 1.741480749654411, "LACOSAMIDE": 1.219592951259355, "LEVETIRACETAM": 1.3061508764605758, "LUMYKRAS": 18.831227719531736, "LYRICA": 2.4181646762087343, "MEKINIST": 4.683314590844747, "MERCAPTOPURINE": 2.5692758690732536, "METHOTREXATE": 1.0891277081315391, "MIDAZOLAM": 4.444385194684785, "NORVIR": 8.065466469323013, "NOVONORM": 4.777065640616162, "NOXAFIL": 14.473180428141289, "OCALIVA": 3.2684359384226678, "OFEV": 1.382538205536249, "OPDIVO": 2.398980272128844, "PANTOPRAZOLE": 6.456960811393289, "PEMBROLIZUMAB": 1.4621404774805518, "PLAVIX": 1.5250992359902966, "POSACONAZOLE": 5.063814515427367, "PREGABALIN": 2.75773629733525, "REBETOL": 2.0124431549484507, "REVATIO": 1.0436361940012078, "REYATAZ": 3.2666343409498584, "ROACTEMRA": 1.3571512600172275, "SOLIRIS": 1.134487928508226, "SUFENTANIL": 6.9087089196938845, "TAMIFLU": 3.3356283298895386, "TEMODAL": 10.202963317414216, "TEMOZOLOMIDE": 3.2985823658421487, "TESTOSTERONE": 3.115088246584666, "TIVICAY": 2.9158428083437973, "TRACLEER": 1.946310929417409, "VEKLURY": 6.920885370136371, "VFEND": 17.574682987499127, "VIMPAT": 1.005087735168554, "VIRAMUNE": 4.318429006362471, "VORICONAZOLE": 9.493769963397629, "VOTRIENT": 1.7656696565209162, "XARELTO": 2.386691429780636, "XELODA": 1.7196554057617397, "YERVOY": 1.381495516994069, "YONDELIS": 8.78889935741572, "ZELBORAF": 2.540538814595917, "null": 2.4045497871051054}
\ No newline at end of file
+{"AFINITOR": 1.8417430508867476, "AMINOSALICYLIC": 8.781584017184526, "ARAVA": 0.1504848105439746, "AVANDIA": 0.4141930348007753, "BEDAQUILINE": 23.183203866524103, "BUMETANIDE": 4.240698395150697, "BYETTA": 0.8611047130434363, "CABOMETYX": 1.7465015694338557, "CELECOXIB": 5.9992140814998285, "CELLCEPT": 1.3259181735772887, "CICLOSPORIN": 0.681911211221647, "CLOPIDOGREL": 0.7206770568539103, "COMIRNATY": 0.0515399331300711, "CYMBALTA": 2.3624390132621955, "CYTARABINE": 1.199929229882496, "DELAMANID": 11.16753490058625, "ELIQUIS": 0.6841192681787432, "EMEND": 4.766771884988119, "ENTRESTO": 4.038709982335565, "ESBRIET": 4.04419923185147, "EXFORGE": 4.7885294592827, "EXJADE": 3.4005929509187056, "FIRDAPSE": 4.26185594098968, "FORSTEO": 0.7230721103039163, "HIZENTRA": 1.5271749788320952, "HUMALOG": 0.5029441987451081, "HYCAMTIN": 8.21096265461587, "IBRANCE": 1.7307405141350134, "INLYTA": 2.060608542929566, "IRBESARTAN": 3.6257053742040894, "JANUMET": 0.8018878715408095, "JANUVIA": 0.5815554097270519, "JARDIANCE": 1.0066251387929783, "KARVEZIDE": 37.23097521524178, "KEPPRA": 1.703766237233897, "KEYTRUDA": 2.344010833982826, "LANTUS": 0.8577802637927662, "LEVEMIR": 1.0037521874752076, "LEVETIRACETAM": 1.418613124359818, "LEVOFLOXACIN": 0.5607274091893822, "LYRICA": 2.1159714534825347, "MEKINIST": 2.35731671167896, "MICARDIS": 5.390516612964055, "NEXAVAR": 1.2196635768839243, "OFEV": 1.0341660975708704, "OLANZAPINE": 1.548604080737337, "OPDIVO": 1.253733176138875, "OPSUMIT": 1.9613342117734271, "PEGASYS": 1.4294229711685342, "PEGINTRON": 0.8577717527886743, "PLAVIX": 0.2995284472231694, "REVATIO": 1.8742438953437237, "RUBRACA": 2.591703245579112, "SPIKEVAX": 0.0970757744595747, "SPRYCEL": 1.0981243601970971, "STELARA": 0.4199476132052207, "STIVARGA": 1.2327839631632698, "SUTENT": 3.658482291174934, "TAGRISSO": 2.0135075514031517, "TOZINAMERAN": 0.3238008676580847, "TRACLEER": 0.7236484226693344, "TRELEGY": 1.4743778223798856, "VAXZEVRIA": 0.0221404435057709, "VFEND": 1.220514612461744, "VIMPAT": 1.6131150404427594, "VOTRIENT": 2.5845965020242723, "XELJANZ": 0.6170851793096036, "XOLAIR": 0.4430229338168974, "XTANDI": 1.2199056272948685, "XYREM": 2.5091136657630977, "YERVOY": 2.480488946750292, "ZOSTAVAX": 0.3066669156368933, "ZYPREXA": 2.450780305457465, "null": 2.037251238611632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1739.json
index ff60593f123..60c4226ce25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1739.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1739.json
@@ -1 +1 @@
-{"DULOXETINE": 59.23908790386782}
\ No newline at end of file
+{"COMIRNATY": 0.0446914834201351, "ESOMEPRAZOLE": 19.544899919126408, "EXJADE": 6.069592874776522, "JARDIANCE": 3.662359960667823, "MICARDIS": 13.962300407961903, "MIDAZOLAM": 12.321635370361424, "OLANZAPINE": 6.541302652071593, "SUTENT": 2.228465916762358, "null": 2.123936539431512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/174.json
index 8f496fef753..3d10e40cbce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/174.json
@@ -1 +1 @@
-{"NAGLAZYME": 117.32806557153818, "null": 2.3318466652000325}
\ No newline at end of file
+{"null": 1.006633644640497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1740.json
index 15b0a036266..663905acc8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1740.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1740.json
@@ -1 +1 @@
-{"BRIDION": 24.540700753929915, "ELIQUIS": 2.4255276601571154, "KEYTRUDA": 2.39679459204543, "LEVETIRACETAM": 5.056525154829041, "MULTAQ": 21.13172429581888, "PLAVIX": 2.6432378196066355, "null": 2.729866538516206}
\ No newline at end of file
+{"SPIKEVAX": 37.66632364261925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1741.json
index ec1ec066290..db1d0a4d7fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1741.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1741.json
@@ -1 +1 @@
-{"null": 1.1037392363797265}
\ No newline at end of file
+{"ALEMTUZUMAB": 183.5071366128074, "CICLOSPORIN": 186.5123341647432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1742.json
index 4025a372d67..038282f8605 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1742.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1742.json
@@ -1 +1 @@
-{"null": 1.5865786303422296}
\ No newline at end of file
+{"GARDASIL": 5.465525774160485, "SPIKEVAX": 13.494651373392143, "VAXZEVRIA": 1.8003035661960405, "null": 0.0897128748546406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1743.json
index 1c0f922c9dc..e0a61037938 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1743.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1743.json
@@ -1 +1 @@
-{"IRINOTECAN": 45.54563049917256, "TRODELVY": 60.423254645511584, "null": 7.848200124263555}
\ No newline at end of file
+{"ACLIDINIUM": 13.871090054510477, "ADALIMUMAB": 0.2267200291224239, "AFINITOR": 0.735395609178613, "ANAKINRA": 2.9860261153995507, "APIXABAN": 74.96607308565218, "ARANESP": 8.899121862981342, "ATRIPLA": 0.1417140003690276, "AUBAGIO": 2.0208139708240136, "BENLYSTA": 2.617379042781179, "BOSULIF": 2.656398791225277, "BUDESONIDE": 13.252594626829008, "CAPECITABINE": 1.574722187278612, "CELLCEPT": 1.1959716154926665, "CIMZIA": 0.5670572951385052, "COMIRNATY": 0.1520470228635017, "CYMBALTA": 0.2725856222032377, "DABRAFENIB": 9.799284165527297, "DAXAS": 50.85673159442715, "ELIQUIS": 3.1702751798236624, "ENTYVIO": 1.7002754358642904, "ESOMEPRAZOLE": 3.845827975270725, "FAMPYRA": 5.659382746614279, "FASLODEX": 1.748921892755784, "FENTANYL": 0.5795170887999357, "FILGRASTIM": 5.862678694532354, "FLUTICASONE": 18.66574066722333, "FORSTEO": 2.070895571845993, "IBRANCE": 9.418933937950497, "IMATINIB": 7.159241529212811, "INLYTA": 1.7648898029483742, "JAKAVI": 2.087914004267117, "JARDIANCE": 0.6001284952411723, "KEPPRA": 0.3280719115544906, "KEYTRUDA": 0.4927029588894378, "KISQALI": 3.143046533979188, "LYNPARZA": 2.4439231246484376, "MEPOLIZUMAB": 5.697699662902504, "METHOTREXATE": 2.060818802267369, "NEULASTA": 2.6430905838124468, "NUCALA": 5.7733825941672565, "OMALIZUMAB": 3.871885739500208, "PEGASYS": 2.8223681388621675, "PEGINTRON": 1.3270101751726513, "PLEGRIDY": 8.543275135642038, "RINVOQ": 1.6380709050087183, "ROACTEMRA": 1.249734978774201, "RUBRACA": 8.182961645812316, "SIMPONI": 3.843730544139679, "SOLIRIS": 1.8126911905429235, "SPIKEVAX": 0.1579472849630893, "SPRYCEL": 1.9451149868023312, "STELARA": 0.8197993950092846, "SUTENT": 2.341882650308621, "TASIGNA": 1.483111905284611, "TOZINAMERAN": 0.7428476463812719, "VAXZEVRIA": 0.2499618909715134, "VENCLYXTO": 9.50939809993904, "VFEND": 1.2264385019281647, "VOTRIENT": 0.9012922634802816, "XELJANZ": 2.9188413749728674, "XOFIGO": 11.548245860798938, "XOLAIR": 1.398651760722725, "XTANDI": 0.7623253049672339, "null": 0.5449257728145451}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1744.json
index e1222eee5a7..98170892ee8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1744.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1744.json
@@ -1 +1 @@
-{"null": 1.7778416994252046}
\ No newline at end of file
+{"SPIKEVAX": 27.287242905205744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1745.json
index f16f76a38d5..a80f9a55c4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1745.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1745.json
@@ -1 +1 @@
-{"METHOTREXATE": 79.55151568043685}
\ No newline at end of file
+{"VIAGRA": 40.49493697391148, "null": 2.735205812871108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1746.json
index 698444d675e..9d98cea4416 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1746.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1746.json
@@ -1 +1 @@
-{"ANAKINRA": 86.67267192740884, "AVAMYS": 58.830644713481}
\ No newline at end of file
+{"ABACAVIR": 1.9895377867272732, "APIDRA": 4.174462589308704, "COMIRNATY": 0.0399787281017553, "LYRICA": 3.07494840240443, "SUBOXONE": 7.849910944851148, "TESTOSTERONE": 85.91153653197748, "VIAGRA": 27.847725306035787, "null": 3.788450634562095}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1747.json
index 7ba31e982cb..28280e3d918 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1747.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1747.json
@@ -1 +1 @@
-{"AVAMYS": 34.86290439608444, "RELVAR": 93.25621789278247, "null": 1.1200816013942618}
\ No newline at end of file
+{"null": 3.409475678587926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1748.json
index 85d79e2fe80..09625d32d70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1748.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1748.json
@@ -1 +1 @@
-{"METHOTREXATE": 433.3969778062538}
\ No newline at end of file
+{"null": 1.5345798162876387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1749.json
index 8282f7b67ba..6b6410967a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1749.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1749.json
@@ -1 +1 @@
-{"DONJOY": 83876.61688034111, "IFLOW": 44027.57818524235}
\ No newline at end of file
+{"TESTOSTERONE": 412.3866340747055, "null": 3.597157218039312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/175.json
index 7faa2a9caf8..6123db8b86a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/175.json
@@ -1 +1 @@
-{"null": 2.0464318866351654}
\ No newline at end of file
+{"null": 0.7237271814845543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1750.json
index bb0f10b430d..0d4f33f246b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1750.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1750.json
@@ -1 +1 @@
-{"null": 1.7106632264816388}
\ No newline at end of file
+{"null": 1.4293166421256611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1751.json
index 6b023145317..b8ceb16adc0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1751.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1751.json
@@ -1 +1 @@
-{"null": 1.009551223095855}
\ No newline at end of file
+{"COMIRNATY": 0.3293847746514843, "IRBESARTAN": 45.9891528125131, "KEYTRUDA": 9.80867037062944, "LEMTRADA": 120.0199448828688, "OPDIVO": 19.05353379167592, "PEGINTRON": 7.516104243376881, "SUTENT": 5.230389051020488, "null": 0.3771936506547207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1752.json
index c2b293590d6..671c49ef2f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1752.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1752.json
@@ -1 +1 @@
-{"ARAVA": 4.359100504768151, "ELIQUIS": 1.5761532230573627, "ESOMEPRAZOLE": 25.659009496854104, "SIMPONI": 6.805798739410735, "VIAGRA": 9.134824202803769, "XELJANZ": 5.712299736421428, "null": 1.3717894331989775}
\ No newline at end of file
+{"ALEMTUZUMAB": 15.07290508158228, "AUBAGIO": 2.1578896725735293, "COMIRNATY": 0.3551992175585346, "KEYTRUDA": 11.615835547584544, "LEMTRADA": 82.55506716577959, "OPDIVO": 10.746159253462151, "PEGASYS": 4.843458456607736, "PEGINTRON": 2.865633780662524, "PROPRANOLOL": 23.302630528282243, "SPIKEVAX": 0.1442610591525498, "SUTENT": 2.0194300089519306, "TOZINAMERAN": 0.5137355935035861, "VAXZEVRIA": 0.0572330952244919, "YERVOY": 15.645556184679588, "null": 1.221862111715115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1753.json
index 48008ece8f4..eed7b92ed5f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1753.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1753.json
@@ -1 +1 @@
-{"null": 3.952252586488466}
\ No newline at end of file
+{"AFINITOR": 1.991118835475008, "ALEMTUZUMAB": 3.08905435011092, "ARIPIPRAZOLE": 7.60986668818652, "AXITINIB": 11.250223539662445, "BAVENCIO": 18.57556911900037, "BEDAQUILINE": 8.214569741601311, "CABOMETYX": 11.05025827243693, "CAPRELSA": 18.479056598280355, "CLOPIDOGREL": 1.642878399595682, "COMIRNATY": 0.3946974484552271, "DELAMANID": 7.788137702732822, "ELIQUIS": 0.436597983392133, "ENTRESTO": 0.8813523374720464, "ERLEADA": 6.171918724559681, "EVEROLIMUS": 7.878227121765229, "GARDASIL": 0.5321610726428273, "INCIVO": 5.017106699976378, "INLYTA": 8.392077989410666, "INTRONA": 7.019218225295544, "KEYTRUDA": 13.781375562862314, "LEMTRADA": 21.867074426987816, "LENVIMA": 14.456303508549514, "METFORMIN": 22.850829720844008, "MULTAQ": 4.8979461643180615, "NEXAVAR": 2.807108039778952, "OPDIVO": 2.940238192872663, "PAZOPANIB": 12.126120596847892, "PEGASYS": 3.965919619290296, "PEGINTRON": 2.6907482269227407, "PEMBROLIZUMAB": 5.544790770129857, "PROPRANOLOL": 6.56941743988233, "SPIKEVAX": 0.1969216738820295, "STIVARGA": 5.465871739228595, "SUTENT": 14.965355726989705, "TOZINAMERAN": 0.3860557784458956, "VAXZEVRIA": 0.0847437407019031, "VOTRIENT": 8.970993236378499, "ZYPREXA": 1.4014942128631973, "null": 0.9200504752237708}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1754.json
index 8a961def9ba..957a079408d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1754.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1754.json
@@ -1 +1 @@
-{"ABACAVIR": 3.7998022292620703, "GARDASIL": 2.1317744436119708, "INSULIN": 5.568995500261613, "OLANZAPINE": 4.670603461658708, "PEGASYS": 2.4858534341170944, "null": 2.784908498041033}
\ No newline at end of file
+{"JANUMET": 13.022812045030404, "SUTENT": 3.5954675891548744, "ZOSTAVAX": 11.961308305789624, "null": 0.7641286119295329}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1755.json
index f559c8dbaf8..77ddb47b1ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1755.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1755.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 18.15947099117203, "ZYPREXA": 4.767504971440186, "null": 4.159022771896933}
\ No newline at end of file
+{"null": 0.5143141970941679}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1756.json
index 49497a2bc16..54edb69a155 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1756.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1756.json
@@ -1 +1 @@
-{"null": 1.906036144418784}
\ No newline at end of file
+{"ABACAVIR": 4.88779787963303, "ABILIFY": 2.60263365811968, "AFINITOR": 5.776243748205767, "ARAVA": 0.1071282857629153, "ARIPIPRAZOLE": 2.534480726308981, "ASPARAGINASE": 2.518795643407307, "ATAZANAVIR": 6.3699527425974525, "ATRIPLA": 0.2665097283537644, "AUBAGIO": 0.9463163061763552, "AVANDIA": 2.735051850598865, "AZATHIOPRINE": 1.0574292085567922, "BIKTARVY": 6.129767437266305, "BYDUREON": 2.5157375051068445, "BYETTA": 7.668896028237928, "CELLCEPT": 0.5302993305847599, "CHAMPIX": 0.7910870064704032, "CICLOSPORIN": 1.0669409784001695, "CLOPIDOGREL": 1.1721922120111503, "COMBIVIR": 2.562798702562856, "COMIRNATY": 0.0851603639001103, "COSENTYX": 1.3911156809792014, "CRIXIVAN": 15.357785872121385, "CYMBALTA": 1.5777494730353228, "CYTARABINE": 1.107424035915897, "DARUNAVIR": 25.917827223869256, "DESCOVY": 9.10357511275836, "DEXAMETHASONE": 0.5220356627431222, "DULOXETINE": 1.5727393818264055, "EFAVIRENZ": 10.750570711305576, "EMTRICITABINE": 5.250018360232792, "ENTRESTO": 3.1193379666092924, "EPIVIR": 7.853861671449067, "ERLEADA": 2.954688166576865, "EVEROLIMUS": 7.099972640559061, "EVISTA": 2.6213510661702606, "EXFORGE": 2.9673874075255724, "FORSTEO": 0.9650686730957246, "FORXIGA": 3.195194767612203, "GALVUS": 5.635058455934962, "GENVOYA": 7.239790169897224, "HUMALOG": 0.7209381981280772, "INCIVO": 1.5107755261222249, "INSULIN": 1.4369806462267067, "INVIRASE": 23.748769832251284, "JAKAVI": 1.6881733571971778, "JANUMET": 3.7737171749258094, "JANUVIA": 2.253327068895556, "JARDIANCE": 1.2311755603204573, "KALETRA": 12.05018826184497, "LAMIVUDINE": 2.870412780134394, "LANTUS": 0.7012663259782258, "LATUDA": 2.547497133082527, "LYRICA": 1.0655836824819236, "NORVIR": 3.241793039219291, "OLANZAPINE": 4.520726051258092, "OZEMPIC": 18.797250515978536, "PANTOPRAZOLE": 3.8668006186248416, "PEGASYS": 2.433619121002644, "PEGINTRON": 1.678930123610531, "RAPAMUNE": 4.7580380974588525, "REMDESIVIR": 9.478127597143688, "REYATAZ": 4.994795360898335, "RINVOQ": 6.08280357680665, "ROACTEMRA": 3.867771006162711, "SIMPONI": 0.673105725626644, "SOLIRIS": 1.1996939772550737, "STELARA": 1.5173710960299849, "STRIBILD": 0.6687305198470872, "SUTENT": 1.6589180330919366, "TASIGNA": 0.9854267424193636, "TORISEL": 13.50879310967688, "TOZINAMERAN": 0.1016646448518915, "TREMFYA": 1.6091253140960575, "TRULICITY": 5.552568769330999, "VAXZEVRIA": 0.0137558642090381, "VIAGRA": 1.3095448687193596, "VICTOZA": 2.762636318469485, "XELJANZ": 1.6589938072636343, "ZYPREXA": 33.84626014211938, "null": 1.1331645353221491}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1757.json
index a9e151b47d9..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1757.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1757.json
@@ -1 +1 @@
-{"BEOVU": 471.1826648627459, "BRAFTOVI": 27.53591418825309, "CASPOFUNGIN": 63.39071887548951, "EYLEA": 36.39259936955911}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1758.json
index 3c979889e21..056e5b4282b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1758.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1758.json
@@ -1 +1 @@
-{"CICLOSPORIN": 16.615393731135896, "null": 1.3942405194459444}
\ No newline at end of file
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1759.json
index dc8341baaa1..7bb38687298 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1759.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1759.json
@@ -1 +1 @@
-{"EYLEA": 35.59455948346369, "null": 2.314194629978571}
\ No newline at end of file
+{"SOLIRIS": 11.147074865013968, "null": 1.2936102025861351}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/176.json
index 3aab1ed0577..ceff9abc278 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/176.json
@@ -1 +1 @@
-{"MIMPARA": 142.36102134351103, "null": 1.6202316014847262}
\ No newline at end of file
+{"ARANESP": 3.2155370306594704, "ARAVA": 0.5565840118441224, "AZATHIOPRINE": 18.10764881670049, "CELLCEPT": 6.807128655697208, "CIALIS": 470.24417195106304, "CICLOSPORIN": 6.873740191550037, "COMIRNATY": 0.2247420047562702, "COSENTYX": 5.070433960298786, "JAKAVI": 16.527244594502537, "MYCOPHENOLATE": 29.976872359533868, "STELARA": 2.1064531941947773, "VEMURAFENIB": 103.93834272041644, "VFEND": 38.725050026833394, "VIAGRA": 5.148200600517941, "VORICONAZOLE": 83.87006766051883, "ZELBORAF": 25.578306046276357, "ZOSTAVAX": 25.114607041160724, "null": 0.4875998036367814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1760.json
index f902d87660e..a0fe683041f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1760.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1760.json
@@ -1 +1 @@
-{"TOPOTECAN": 3234.0518187156263}
\ No newline at end of file
+{"CELECOXIB": 21.961234813844317, "COMIRNATY": 0.1510407788712527, "EMEND": 52.37347235055133, "ESOMEPRAZOLE": 37.74960057265469, "EXJADE": 5.791122947023763, "GARDASIL": 2.9716137295692797, "OLANZAPINE": 13.90644862579135, "PEGASYS": 1.5585955443068484, "null": 1.12521793079417}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1761.json
index 665e8a9c77b..704ffd0bd62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1761.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1761.json
@@ -1 +1 @@
-{"null": 4.766080694878947}
\ No newline at end of file
+{"ACTOS": 2.7035756497241588, "AFINITOR": 1.860588164925423, "ALIMTA": 1.2118839614421908, "AMINOSALICYLIC": 1.246751560923281, "ANAKINRA": 1.4644379548035362, "APROVEL": 2.3481193306490296, "ARAVA": 0.1509940072677894, "ARIPIPRAZOLE": 2.654226239644935, "ASPARAGINASE": 1.4235671972191215, "ATRIPLA": 0.1114512098093112, "AVANDIA": 0.645583346347236, "BARACLUDE": 6.882917689052484, "BEDAQUILINE": 1.7837782474744777, "BEVACIZUMAB": 1.1519043496385448, "BRILIQUE": 1.4192490422820865, "BUMETANIDE": 3.896770444755978, "BUSULFAN": 1.3326972617493362, "BYETTA": 1.3848343324166144, "CELECOXIB": 14.459985007011982, "CELLCEPT": 1.8630023596764875, "CICLOSPORIN": 3.673723938250348, "CLOPIDOGREL": 1.841496834257759, "COAPROVEL": 2.789654954157086, "COMBIVIR": 1.5546983503808962, "COMIRNATY": 0.0467511667047157, "COSENTYX": 0.22641629081808, "CRIXIVAN": 9.30572159573579, "CUBICIN": 1.9830073024781367, "CYMBALTA": 0.3003599572248124, "CYTARABINE": 0.9591616791419224, "DELAMANID": 3.247060573801644, "DELTYBA": 26.34738675984425, "DENOSUMAB": 4.096522747734538, "DEXAMETHASONE": 0.431321686581581, "ELIQUIS": 0.3731480747106537, "EMEND": 2.7560912039608323, "ENTRESTO": 9.26840210392079, "EPIVIR": 1.6739200346871013, "EVEROLIMUS": 4.669591411647087, "EXFORGE": 3.770019833945181, "EXJADE": 15.412722482895717, "FASLODEX": 0.7955464676636435, "FEBUXOSTAT": 3.647447341047908, "FENTANYL": 0.7521132664422348, "FORXIGA": 3.065349153823127, "GALVUS": 3.4182265517851174, "GLIVEC": 2.895534618079424, "HUMALOG": 0.3291350637610578, "HUMIRA": 0.4728707453228646, "HYCAMTIN": 5.375157798213568, "IBRANCE": 0.5501087081467603, "IBUPROFEN": 3.1689928655357806, "INLYTA": 1.5977658832035693, "INSULIN": 0.5234361602910761, "IRBESARTAN": 1.3669238590550397, "ISOPHANE": 27.438388995160302, "JAKAVI": 1.3085265494595282, "JANUMET": 0.7890820494613514, "JANUVIA": 0.709338142537352, "JARDIANCE": 0.6584565206854179, "KEPPRA": 0.1823392658080612, "KEYTRUDA": 0.6624992912895246, "KYMRIAH": 0.8931629945030373, "LANTUS": 0.5094565459297948, "LEVETIRACETAM": 0.3643476149328415, "LEVOFLOXACIN": 1.8926386702842928, "LYRICA": 0.9794642007203204, "MEKINIST": 0.5150624377704731, "METHOTREXATE": 0.3316180252255552, "MICARDIS": 7.7880270138163, "MIDAZOLAM": 0.8556537729726104, "MULTAQ": 3.67620570405038, "MYCOPHENOLATE": 1.2673170310511686, "NEXAVAR": 0.7005087459019761, "OLANZAPINE": 1.3305150499560845, "OPSUMIT": 1.2383096779415637, "PANTOPRAZOLE": 3.17985584938746, "PEGASYS": 0.4647983148496946, "PEGINTERFERON": 2.052053170207212, "PLAVIX": 0.9749618740070494, "RASILEZ": 18.10853668605657, "REMDESIVIR": 4.539539423075138, "RIVAROXABAN": 7.403863647950863, "RUBRACA": 1.5164969818235234, "SAMSCA": 16.712761217307744, "SOLIRIS": 3.46748611787698, "SPIKEVAX": 0.0549757977675949, "SPIRONOLACTONE": 7.34362224347695, "STIVARGA": 0.5011967037015198, "SUTENT": 2.2121166612252656, "TAMIFLU": 0.7514914977520809, "TASIGNA": 0.995710147466928, "TELMISARTAN": 3.140265540239677, "TENOFOVIR": 8.805888805590932, "TOBRAMYCIN": 11.694635508630489, "TORISEL": 4.145565248902495, "TOZINAMERAN": 0.0744748940699609, "TRACLEER": 0.6450569765418719, "TRUVADA": 0.2689478065548182, "VALSARTAN": 6.219175477943817, "VFEND": 1.140541804061436, "VIREAD": 2.15818720768301, "VOTRIENT": 0.6364514793652638, "XOLAIR": 0.3849766505564651, "ZOMETA": 10.988333564731985, "ZONISAMIDE": 10.683918867731062, "ZOSTAVAX": 0.4235578554164815, "ZYPREXA": 0.8646988209311096, "null": 2.405045419420692}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1762.json
index b7b1087d842..b30067de1a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1762.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1762.json
@@ -1 +1 @@
-{"null": 4.496029359065561}
\ No newline at end of file
+{"null": 1.5854742411385632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1763.json
index dfbc6f4b342..36574eb900f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1763.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1763.json
@@ -1 +1 @@
-{"BEOVU": 360.2528882273764, "EYLEA": 137.8067419704543}
\ No newline at end of file
+{"ENTRESTO": 14.509370548118682, "null": 0.6964142060717463}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1764.json
index 7cf5061d067..a15eaa5be56 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1764.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1764.json
@@ -1 +1 @@
-{"MYCOPHENOLATE": 207.8826678735093}
\ No newline at end of file
+{"SPIKEVAX": 35.02909825914515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1765.json
index 55917b6cd67..403c6609ca8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1765.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1765.json
@@ -1 +1 @@
-{"VFEND": 151.94192232343244, "VIAGRA": 38.11186535611529, "VORICONAZOLE": 31.27365558416451, "null": 1.0111267676172824}
\ No newline at end of file
+{"null": 1.3582386685205834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1766.json
index 9a3eed51e08..a0d38f1572b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1766.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1766.json
@@ -1 +1 @@
-{"ARIXTRA": 11.441608480541724, "AUBAGIO": 1.1398097367998503, "BETAFERON": 1.45296181599775, "BIKTARVY": 1.2278255462958765, "CLOPIDOGREL": 1.3010804054399756, "COMBIVIR": 1.4404374073586206, "COMTAN": 15.02122212759018, "CYMBALTA": 1.01082879227659, "ELIQUIS": 1.5303595365845235, "ENOXAPARIN": 1.188580807315897, "ENTACAPONE": 10.166329997854277, "ESBRIET": 1.278947996977417, "EUCREAS": 4.015750077957812, "EXFORGE": 1.8069422790799328, "EXJADE": 4.765211081937268, "EXVIERA": 3.0008808850100834, "FORXIGA": 1.5576112773847646, "GALVUS": 2.939282431119877, "HUMAN": 1.1996529831787102, "IBUPROFEN": 1.6108478603613563, "IRBESARTAN": 1.8693204861536643, "JANUVIA": 1.0620509039793595, "KAFTRIO": 2.060491027700013, "KETEK": 14.048979455581048, "KISQALI": 1.3846720477469627, "LEMTRADA": 1.741266924028328, "LEVOFLOXACIN": 1.0670727495922332, "LIXIANA": 3.146456318444303, "LONSURF": 4.276619544596277, "MEKINIST": 1.3186200936188213, "MICARDIS": 2.080576936172821, "MULTAQ": 3.3400013365444763, "NEVANAC": 8.273675765276668, "OCALIVA": 5.281365597074943, "PEGASYS": 1.8450625252685888, "PEGINTRON": 1.4017803424500066, "PLAVIX": 1.343718791628571, "PRIVIGEN": 2.622878860751225, "RANEXA": 14.44729951282272, "RANOLAZINE": 7.140668111941144, "RASBURICASE": 25.7463132108657, "RIBAVIRIN": 1.2162359695759113, "SIFROL": 2.81198359050999, "SOLIRIS": 13.05094762921445, "STALEVO": 20.417729351749163, "STIVARGA": 3.289256791702419, "SUTENT": 3.326256621772179, "TAMIFLU": 5.318184432389533, "TASIGNA": 1.3488045460365232, "TOVIAZ": 1.4857624759264851, "TRACLEER": 1.3850727076946838, "TRIUMEQ": 2.6363422670054346, "TWINRIX": 2.3549682693385887, "VOTRIENT": 1.587463128276142, "XARELTO": 1.6661899677072214, "XTANDI": 1.045931451524202, "null": 2.1664074045570194}
\ No newline at end of file
+{"HEPSERA": 225.6894386343257, "null": 0.6913455571669485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1767.json
index 8ddaa20c8a8..db54c417d9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1767.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1767.json
@@ -1 +1 @@
-{"null": 1.319335982684351}
\ No newline at end of file
+{"ANAKINRA": 3.705248222981089, "APROVEL": 4.358617444526064, "ARANESP": 128.65282481003018, "BRILIQUE": 10.9949462055992, "CELLCEPT": 1.3686032850302845, "CICLOSPORIN": 1.9666331390347405, "CLOPIDOGREL": 0.4420347590880058, "COAPROVEL": 12.06578080543801, "COMIRNATY": 0.102495095939273, "COSENTYX": 0.5052952890343219, "CYMBALTA": 1.170640657807227, "DARBEPOETIN": 80.88319461086844, "ELIQUIS": 0.6518772176774348, "EMPAGLIFLOZIN": 8.696923788584629, "ENTRESTO": 5.993897309208055, "EXFORGE": 3.476014068825986, "EXJADE": 1.3473071021045386, "FASTURTEC": 59.56608188824778, "FEBUXOSTAT": 10.315619217620414, "FORSTEO": 7.3133874597412465, "INCIVO": 10.641717064275609, "JAKAVI": 2.0642300582126536, "LANTUS": 0.348374597622048, "MELATONIN": 8.689512455766716, "MICARDIS": 6.079852143823153, "NEXAVAR": 0.9800236790894244, "OLANZAPINE": 0.8719589124690457, "OZEMPIC": 20.191147906856116, "PEGASYS": 2.2211819539518656, "PEGINTERFERON": 4.5403269253159015, "PEGINTRON": 6.849380935879915, "RASILEZ": 7.805911395008172, "REBETOL": 6.69092896809856, "SUTENT": 2.141007434981585, "VENETOCLAX": 5.924699836168286, "ZYPREXA": 0.4827019246140644, "null": 1.0061193671051}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1768.json
index 3b60f76cb21..2626bc15737 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1768.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1768.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 23.008132291208053, "BASILIXIMAB": 304.555245457088, "CELLCEPT": 38.45892521330973, "CICLOSPORIN": 97.94922513786184, "MYCOPHENOLATE": 80.89388865194267}
\ No newline at end of file
+{"VOTRIENT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1769.json
index 7be1fd3212b..c8139113309 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1769.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1769.json
@@ -1 +1 @@
-{"BENLYSTA": 25.003281218748143, "HUMIRA": 21.63308931377145, "null": 1.030583752143526}
\ No newline at end of file
+{"COMIRNATY": 0.6961308622943215, "SPIKEVAX": 0.7250544693965214, "SUTENT": 7.691496680003189, "TOZINAMERAN": 1.7711802140688346, "VAXZEVRIA": 0.9432282925140276, "null": 0.7666716630357225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/177.json
index ada68bb97fa..aeba7fef563 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/177.json
@@ -1 +1 @@
-{"COMIRNATY": 4.246909728886785, "ESMYA": 184.05825029246887}
\ No newline at end of file
+{"ZOMETA": 455.2063790686895, "null": 0.5493432248751642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1770.json
index a85596235f0..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1770.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1770.json
@@ -1 +1 @@
-{"COSENTYX": 23.99814600976756, "STELARA": 26.21151830536997}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1771.json
index 74712aa7ac8..739bd24c7cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1771.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1771.json
@@ -1 +1 @@
-{"COMIRNATY": 4.591700454870085, "COVID19": 1.588400911879429, "ESOMEPRAZOLE": 4.435906274568137, "GARDASIL": 16.984119810590094, "IXIARO": 55.21397282854985, "SPIKEVAX": 1.8932645051235504, "TOZINAMERAN": 2.8100010526439, "TWINRIX": 13.039041357385424, "VAXZEVRIA": 1.392147054144186}
\ No newline at end of file
+{"AFINITOR": 2.505111595242968, "ALEMTUZUMAB": 10.38149405261197, "APIXABAN": 0.6178611540222768, "ARAVA": 0.1029006693163115, "ATRIPLA": 0.5297823947507762, "AUBAGIO": 0.6156647496835342, "BENLYSTA": 0.9305038090865004, "BETMIGA": 6.610177408113944, "BRILIQUE": 1.1614838237339649, "CHAMPIX": 1.0727132995790218, "CICLOSPORIN": 0.440662153931417, "CIMZIA": 0.4476016940820697, "CLOPIDOGREL": 1.7041767987939185, "COMIRNATY": 0.3495574488969457, "COSENTYX": 0.7286677407783518, "CYMBALTA": 0.2811247798576909, "DULOXETINE": 6.925197474181946, "ELIQUIS": 10.848423195061857, "ESBRIET": 1.7776849013743194, "EXFORGE": 0.9876543545060912, "EXJADE": 2.799774651437241, "FASLODEX": 0.8531781287506464, "FORXIGA": 1.384709187945721, "GARDASIL": 0.5787946778086117, "HEMLIBRA": 12.771701943754934, "HUMALOG": 0.3537783769069382, "HUMIRA": 0.9937656276823288, "IBRANCE": 0.5188193218742109, "INLYTA": 1.3611506276495169, "JARDIANCE": 2.125704383476572, "LANTUS": 0.7059028609512222, "LEMTRADA": 3.8270475160173096, "LIXIANA": 35.401728374591656, "LYRICA": 1.4973968007907892, "NEXAVAR": 0.5658846275498876, "NUCALA": 0.669754019883854, "OMALIZUMAB": 4.1951227717002055, "PEGASYS": 1.9981971953597024, "PEGINTRON": 0.478116380477751, "PLAVIX": 3.771466632492318, "RIBAVIRIN": 1.243198497682054, "RITUXIMAB": 1.7151053068577, "SILDENAFIL": 2.153303563139485, "SIMPONI": 0.5963676238993505, "SOLIRIS": 4.953933738107312, "SPIKEVAX": 0.3801266897495119, "STELARA": 0.9227053321778904, "SUTENT": 4.383643330079826, "TOVIAZ": 6.4138136772640895, "TOZINAMERAN": 1.0778037437185797, "TRUVADA": 0.3834818326487089, "VAXZEVRIA": 0.3129689388604287, "VIAGRA": 3.7674588622550753, "VOTRIENT": 3.691495286575616, "XARELTO": 12.087292543389566, "XELJANZ": 1.421977596452599, "XOLAIR": 0.5007921027249199, "XTANDI": 10.157948898610009, "ZOSTAVAX": 0.6817105146048522, "ZYPREXA": 0.6014263985762516, "null": 0.9981976139783028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1772.json
index e729441af91..d200a60533d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1772.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1772.json
@@ -1 +1 @@
-{"BYETTA": 3.4449357244123275, "CLOPIDOGREL": 17.04574887142867, "GARDASIL": 1.0562793397355523, "HUMALOG": 1.7081415713772377, "IPILIMUMAB": 8.301569175555496, "JANUMET": 8.126706467526548, "JANUVIA": 5.026518104156921, "KEYTRUDA": 2.1285606587851618, "NEXAVAR": 1.608843979105173, "OPDIVO": 3.407306997076868, "PLAVIX": 4.165668029460797, "TICAGRELOR": 48.18818488575063, "null": 1.2171171269268342}
\ No newline at end of file
+{"null": 0.6604911223137445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1773.json
index e82de7c806c..6b390e910bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1773.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1773.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 92.54985200379114, "null": 1.0791703925161975}
\ No newline at end of file
+{"null": 1.6237216251425384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1774.json
index 29bc1854698..54dbf58ea05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1774.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1774.json
@@ -1 +1 @@
-{"ABATACEPT": 1.0498583830016723, "ALEMTUZUMAB": 23.88828271556361, "ASPARAGINASE": 13.37380877133634, "AZACITIDINE": 12.588829711661024, "AZATHIOPRINE": 21.575669343844865, "BUSILVEX": 92.25667860801164, "BUSULFAN": 170.66887498562906, "CICLOSPORIN": 141.35209015176216, "CYTARABINE": 4.380936863763312, "DEXAMETHASONE": 2.1893186620971488, "IMATINIB": 56.18357150192813, "JAKAVI": 7.726530333577084, "MELPHALAN": 29.982214913207343, "METHOTREXATE": 5.662895687414068, "MYCOPHENOLATE": 25.5321948162184, "RUXOLITINIB": 29.79428541269381, "THIOTEPA": 39.84050064061359}
\ No newline at end of file
+{"CYMBALTA": 11.11034861583951, "ELIQUIS": 7.755114582331676, "null": 1.114306505069158}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1775.json
index 3e8b650b851..90eef23deff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1775.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1775.json
@@ -1 +1 @@
-{"BUSULFAN": 138.414886265655, "CICLOSPORIN": 94.8951821043728}
\ No newline at end of file
+{"ENOXAPARIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1776.json
index 19f19ffb5ca..72f9d56c83f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1776.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1776.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 58.221015752229405, "BUSULFAN": 107.35096369770751, "CICLOSPORIN": 123.3465556989358}
\ No newline at end of file
+{"HUMALOG": 27.847491024637687, "null": 0.656008667067914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1777.json
index ba0585af515..c2fd90c860a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1777.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1777.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 84.82905826222768, "BUSULFAN": 138.67113462874983, "CICLOSPORIN": 108.35174259408711, "MYCOPHENOLATE": 30.61991320903457, "THIOTEPA": 192.51735717586604}
\ No newline at end of file
+{"ARAVA": 3.166932900396348, "COMIRNATY": 0.97628087793856, "PLAVIX": 4.296441736643694, "SPIKEVAX": 0.5361275033134785, "TOZINAMERAN": 1.3717711276936717, "VAXZEVRIA": 0.7421866632658137, "null": 0.7328948125120985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1778.json
index 1963a464525..9267f17ed47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1778.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1778.json
@@ -1 +1 @@
-{"CICLOSPORIN": 27.299926195105403}
\ No newline at end of file
+{"null": 6.798293997947634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1779.json
index 647c96e418a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1779.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1779.json
@@ -1 +1 @@
-{"PEGASYS": 8.225071437874885}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/178.json
index 32d27c933d3..67a5ee7693b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/178.json
@@ -1 +1 @@
-{"COMBIVIR": 477.097705543272}
\ No newline at end of file
+{"KISQALI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1780.json
index cf8e950d1d9..631697746e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1780.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1780.json
@@ -1 +1 @@
-{"CICLOSPORIN": 5.617285407263406, "null": 2.4014421886678017}
\ No newline at end of file
+{"COMIRNATY": 0.5901761016503742, "ELIQUIS": 3.395225821520656, "SPIKEVAX": 0.5928440207113551, "TOZINAMERAN": 3.8178561489800327, "VAXZEVRIA": 1.3007692332828498, "null": 1.1309823523699856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1781.json
index 0d2cedcf1d4..e36688048f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1781.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1781.json
@@ -1 +1 @@
-{"TENOFOVIR": 389.0990288891209}
\ No newline at end of file
+{"LATUDA": 30.981787930057248, "OLANZAPINE": 16.252891053155338, "null": 2.9537523482467973}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1782.json
index d3892388519..398af79888b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1782.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1782.json
@@ -1 +1 @@
-{"CICLOSPORIN": 4.884481624338068, "DACLATASVIR": 153.81904732081443, "DELAMANID": 84.48300349248355, "PEGASYS": 9.53626242358278, "PEGINTERFERON": 87.96849830878531, "RIBAVIRIN": 21.21490797082938}
\ No newline at end of file
+{"ARIPIPRAZOLE": 28.42120188953433, "null": 2.1856024789080752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1783.json
index edd8c0aa7f4..55d4257a072 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1783.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1783.json
@@ -1 +1 @@
-{"COMIRNATY": 2.639632555237601}
\ No newline at end of file
+{"null": 0.9337166011283496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1784.json
index 452129cded4..579f3b969b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1784.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1784.json
@@ -1 +1 @@
-{"AZILECT": 155.5359141649399, "COMBIVIR": 9.845456742801852, "GARDASIL": 2.72362327558573, "HIZENTRA": 58.07516676876715, "PEGASYS": 1.662631314555025, "PEGINTRON": 4.511070856971684, "PRIVIGEN": 29.24673654037771, "SPIKEVAX": 1.2805778675545514, "TOZINAMERAN": 1.1884346052225871, "VAXZEVRIA": 2.3128865262281417, "ZOSTAVAX": 7.049010180928649}
\ No newline at end of file
+{"null": 2.04906311183661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1785.json
index 448c49466f1..2faa425b784 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1785.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1785.json
@@ -1 +1 @@
-{"ATRIPLA": 54.30446761194408, "AVONEX": 3.082942409234644, "BIKTARVY": 1.128703499445341, "BYETTA": 1.458106461220335, "CELSENTRI": 1.4227299416999557, "DAPAGLIFLOZIN": 1.8524729447751795, "DESCOVY": 1.0865244128921976, "DULAGLUTIDE": 1.6586071226272032, "EMTRICITABINE": 1.0657293114331898, "ENTECAVIR": 1.5122356236637355, "FEBUXOSTAT": 1.7415571486082408, "GENVOYA": 1.5339107647588557, "INTELENCE": 1.111241962458792, "INVIRASE": 1.691074619656139, "KALETRA": 3.676660290626268, "KARVEA": 1.5326120324147736, "MICARDIS": 1.1538363775674194, "OZEMPIC": 2.568537108882143, "PANTOPRAZOLE": 1.432153058934088, "SPIRONOLACTONE": 1.155655617679143, "STRIBILD": 29.96690061694021, "TENOFOVIR": 14.40170331232908, "THIOTEPA": 1.0506288526427014, "TIVICAY": 1.7875259076551355, "TRUVADA": 45.10558066350288, "UNSPECIFIED": 1.535216965908851, "VIREAD": 21.521353315105976, "ZOMETA": 1.476475299583552}
\ No newline at end of file
+{"ABATACEPT": 23.43303418319124, "ADALIMUMAB": 44.04109338159553, "ANAKINRA": 277.9436096441469, "null": 0.2777143049505746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1786.json
index 4537881364a..d62bd7d7a3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1786.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1786.json
@@ -1 +1 @@
-{"ATRIPLA": 48.94111877355381, "STRIBILD": 14.579060174187846, "TRUVADA": 30.366109952556187}
\ No newline at end of file
+{"APIXABAN": 2.148871548422508, "ARAVA": 0.2514003257285763, "ATRIPLA": 0.50442073685043, "BUDESONIDE": 2.179231760351313, "BYDUREON": 9.564275572231058, "BYETTA": 5.856380915118072, "CELLCEPT": 1.745991479407543, "CYMBALTA": 2.384160705732808, "ELIQUIS": 5.260621265481978, "ENBREL": 1.8707525252173292, "EVISTA": 49.27713546652811, "FASENRA": 3.036150390226166, "FASLODEX": 12.634529260026987, "FORSTEO": 1.831208111858439, "FULVESTRANT": 4.469288572971133, "HUMALOG": 1.9539138813435728, "IBRANCE": 5.219122545171883, "LYRICA": 6.77119319297698, "PLAVIX": 1.7098121868451004, "RAPAMUNE": 6.115499481562083, "REVATIO": 16.474720539062048, "SIMPONI": 2.6014124389925875, "SUTENT": 1.5754893303346345, "TAGRISSO": 4.185769001700461, "TOVIAZ": 17.66579520163965, "TOZINAMERAN": 0.3054541807965001, "TRUVADA": 0.3412897719055406, "VIAGRA": 3.0738442587627364, "XELJANZ": 4.108922759887753, "null": 2.3266932573200605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1787.json
index 68eadfcbc86..fb5a17f0407 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1787.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1787.json
@@ -1 +1 @@
-{"ELIQUIS": 10.640130447044134, "ONGLYZA": 1410.3886988342722, "SPIKEVAX": 1.8838352300445576, "ZOSTAVAX": 42.45776242319851}
\ No newline at end of file
+{"null": 1.1637784968729086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1788.json
index 721b0162511..49cf2a22a6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1788.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1788.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 7.409467667290668, "ARZERRA": 162.22256830834638, "CYTARABINE": 3.991357663434518, "DEXAMETHASONE": 1.990816865310338, "EXJADE": 5.5681860657286135, "HUMALOG": 1.037309700032956, "IBRUTINIB": 316.67272627766965, "IMBRUVICA": 135.1061443231389, "JAKAVI": 4.375597144978277, "NPLATE": 65.19615218052027, "OBINUTUZUMAB": 32.88237100336362, "OFATUMUMAB": 170.2732843630645, "RITUXIMAB": 22.212136918986264, "SIMPONI": 2.020569528580177, "STELARA": 2.3991604494744405, "VENCLYXTO": 193.73324655325067, "VENETOCLAX": 180.39557737416865, "ZOSTAVAX": 1.6164703174934196}
\ No newline at end of file
+{"FORXIGA": 37.33757606767102, "ZOSTAVAX": 238.96732299876535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1789.json
index a7fad035edb..1bb2996597a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1789.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1789.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 11.562296381116036, "DOXORUBICIN": 49.77560763297469, "GAZYVARO": 153.9177200122778, "IBRUTINIB": 753.4167143014894, "IMBRUVICA": 199.70422061659372, "RITUXIMAB": 33.993158171978635, "VENCLYXTO": 195.74492636581317, "VENETOCLAX": 121.38606270607632}
\ No newline at end of file
+{"APIDRA": 19.289516663745637, "CLOPIDOGREL": 10.410289491850452, "ENTRESTO": 58.2699137992591, "null": 0.4412658135574317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/179.json
index 9e2b41c6c72..e680461ec7e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/179.json
@@ -1 +1 @@
-{"CELLCEPT": 87.85964759676507, "CICLOSPORIN": 55.0830766267274}
\ No newline at end of file
+{"METHOTREXATE": 27.828116999397658, "null": 1.5983101521985676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1790.json
index 017fd4df90b..1981c74973b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1790.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1790.json
@@ -1 +1 @@
-{"BOSULIF": 44.31738130229738, "BOSUTINIB": 189.04989839704544, "BUSULFAN": 4.06699021696152, "CELLCEPT": 1.853456592568804, "CICLOSPORIN": 3.71340496791283, "CYTARABINE": 3.415735213168298, "DASATINIB": 182.35477533878944, "DEXAMETHASONE": 1.4215329817347262, "DOCETAXEL": 2.7165864046703736, "DOXORUBICIN": 5.427430558132807, "GLIVEC": 71.92088625322938, "ICLUSIG": 233.67049887803984, "IMATINIB": 96.9391996516454, "IRINOTECAN": 8.468102811618309, "JAKAVI": 7.045606775168763, "NILOTINIB": 158.3877757950397, "NPLATE": 7.391607919050483, "PLAVIX": 1.1142339696043833, "RITUXIMAB": 2.834794600584142, "SPRYCEL": 31.67543986635461, "STELARA": 2.346138567019594, "TASIGNA": 172.46878921990853, "XELJANZ": 1.3161410343743618}
\ No newline at end of file
+{"ARIPIPRAZOLE": 11.418051915576209, "AVAMYS": 45.6971118841744, "INSULIN": 8.287999087894026, "KAFTRIO": 20.140087967241715, "OLANZAPINE": 8.072013041863611, "ZOSTAVAX": 36.3659100012554, "ZYPREXA": 3.419602997968908, "null": 0.5127765171066992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1791.json
index 52ce4438c80..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1791.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1791.json
@@ -1 +1 @@
-{"BOSUTINIB": 263.8626742984155, "DASATINIB": 598.3027199529947, "ICLUSIG": 367.26038042018, "IMATINIB": 141.45313302170487, "NILOTINIB": 426.109057707447, "SPRYCEL": 67.695276543408, "TASIGNA": 87.34681272528503}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1792.json
index 295a2f9b3c0..182f8042971 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1792.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1792.json
@@ -1 +1 @@
-{"ICLUSIG": 388.9019820992351, "NILOTINIB": 427.7568557672759, "SPRYCEL": 63.33824132155883, "TASIGNA": 260.0588765360084}
\ No newline at end of file
+{"IBRANCE": 133.4727678337479, "INLYTA": 124.65937704731576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1793.json
index 653816f4068..7fae889d315 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1793.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1793.json
@@ -1 +1 @@
-{"NPLATE": 94.18328327149382, "null": 1.0457229902370009}
\ No newline at end of file
+{"IBRANCE": 127.39273568663631}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1794.json
index 0262d063002..84e63d4be94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1794.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1794.json
@@ -1 +1 @@
-{"ACLIDINIUM": 29.154484678147117, "ADCIRCA": 1.285848411927477, "AERIUS": 1.212122147528948, "ANORO": 16.10641401225638, "APIXABAN": 1.0050414976893998, "ARANESP": 11.385967528329813, "AVAMYS": 10.079534371712144, "AVANDAMET": 2.151260034691944, "AVANDIA": 2.211175090819899, "BEDAQUILINE": 3.1307061051173064, "BEVESPI": 34.20696330066647, "BLINDED": 10.863595264000493, "BRETARIS": 141.20322855998197, "BUDESONIDE": 3.016430261531852, "BYDUREON": 1.4286834510633035, "BYETTA": 1.5805453521992572, "CANAGLIFLOZIN": 6.230710300258888, "CANCIDAS": 1.0089584102464328, "CIALIS": 1.5970344065105415, "CLOPIDOGREL": 1.0421620463029275, "DALIRESP": 48.60039458391499, "DAXAS": 12.746683007749708, "DELAMANID": 3.729251718997103, "DUORESP": 11.451790987034324, "ELIQUIS": 1.8128925325726728, "ENTRESTO": 1.705556070865638, "EPADERM": 45.24116119535811, "ESBRIET": 2.0358884471745107, "EVENITY": 1.2241046648130305, "EVISTA": 1.646615685519682, "FASENRA": 2.562956076023725, "FIRDAPSE": 1.3135861984503563, "FLUTICASONE": 17.08910215185045, "FORSTEO": 1.7227011139499568, "GLYCOPYRRONIUM": 27.272757732136984, "HIZENTRA": 2.6881019632280445, "HUMALOG": 2.071451752506519, "INCRUSE": 44.25154855779144, "INVOKANA": 1.6346485525843415, "IRBESARTAN": 1.036329131266486, "IRON": 4.870584049920035, "JANUMET": 1.8782572395250683, "JANUVIA": 3.046042114918674, "LANTUS": 1.6118507358313705, "LEVEMIR": 1.38625388729384, "LYRICA": 2.2559603281490035, "MEPOLIZUMAB": 5.36357849397271, "MULTAQ": 1.5199605127729694, "NOT": 1.0006285599717957, "NPLATE": 2.272520148987166, "NUCALA": 2.74879855952992, "OMALIZUMAB": 3.066744377771093, "ONBREZ": 27.054889076649783, "ONGLYZA": 2.5208491743472883, "OPSUMIT": 3.2138893862480225, "PANTOPRAZOLE": 3.0829464379528, "PREGABALIN": 1.0365068313268708, "RELVAR": 6.213368967533156, "REVATIO": 8.303919162191285, "REYATAZ": 1.5478229639784982, "RIVAROXABAN": 3.839103435986262, "SEEBRI": 11.00004518009037, "SILDENAFIL": 1.3435711047157013, "SPIRONOLACTONE": 1.266135873220502, "SPRYCEL": 1.3105653111223703, "TASIGNA": 1.2029080905204212, "TRACLEER": 3.4988913242046955, "TRELEGY": 43.05834320283177, "TREMFYA": 1.2699353818074448, "ULTIBRO": 34.97678144663863, "UMECLIDINIUM": 49.250276573397855, "VALSARTAN": 1.6345591665039128, "VELTASSA": 1.590571778472316, "VFEND": 1.2486693509512885, "VIAGRA": 1.1104255362989452, "XARELTO": 2.593022001589105, "XELJANZ": 1.4598880469772455, "XOLAIR": 2.6170288884405863, "XTANDI": 1.1151604344787118, "ZOMETA": 4.592053406444897, "ZOSTAVAX": 5.565360111693838, "null": 2.026162680032986}
\ No newline at end of file
+{"ABATACEPT": 2.253260601374896, "BYDUREON": 5.056963543174196, "COMIRNATY": 0.6430366292198644, "OCRELIZUMAB": 11.43765595591051, "SPIKEVAX": 1.3102958758555088, "STELARA": 1.694488179578304, "TOZINAMERAN": 1.2173840662895823, "VAXZEVRIA": 19.52956912909431, "null": 0.0545147185207176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1795.json
index d218cb7483b..0105d25b86f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1795.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1795.json
@@ -1 +1 @@
-{"EFAVIRENZ": 170.11803473857734, "SYNAGIS": 186.17440420032395}
\ No newline at end of file
+{"ABILIFY": 2.295687722819652, "COMIRNATY": 1.8664156571286183, "NEULASTA": 3.370314982099754, "SPIKEVAX": 2.0117305557644523, "TOZINAMERAN": 2.828660411018392, "VAXZEVRIA": 6.432497004454748, "null": 0.1563307058063761}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1796.json
index 124459627ac..d12381efc41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1796.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1796.json
@@ -1 +1 @@
-{"BEDAQUILINE": 23.680890528521623, "ESBRIET": 16.04220473756539, "OCEAN": 1247.990565363114, "OFEV": 19.23280302137393, "OPSUMIT": 10.753568419610849, "REVATIO": 22.147652394083053, "SPINRAZA": 83.49504945234207, "SYNAGIS": 30.29644419137296, "TRACLEER": 28.86776117167693, "ZOSTAVAX": 6.331923596071674}
\ No newline at end of file
+{"ABILIFY": 2.4339677329117886, "ADALIMUMAB": 0.3576770087478445, "AFINITOR": 6.274317741678512, "APIDRA": 1.7532814809956525, "APIXABAN": 0.98559436539958, "ARAVA": 0.4523623986554826, "BEVACIZUMAB": 7.169260074156138, "BUDESONIDE": 0.7938513885847633, "CELLCEPT": 0.7280400926452016, "COMIRNATY": 0.7662753512351664, "COSENTYX": 3.9650994525633863, "DULOXETINE": 3.846709496986099, "ELIQUIS": 0.4877165655826844, "EVEROLIMUS": 5.794183636533713, "GARDASIL": 0.3156886443348365, "HUMALOG": 0.842593323301961, "IBUPROFEN": 0.8905120165639279, "IRBESARTAN": 4.212431284272316, "KEPPRA": 0.7166907614304762, "LANTUS": 0.7754156733043982, "LUTETIUM": 29.588294205029012, "METHOTREXATE": 6.251105016337291, "MMRVAXPRO": 6.548659433986612, "NOT": 3.2569288712147344, "OLANZAPINE": 0.5730411174457904, "OMALIZUMAB": 24.372736471663178, "PANTOPRAZOLE": 20.31554680398081, "PEGASYS": 0.3540740818500783, "RITUXIMAB": 6.597304423277463, "SPIKEVAX": 0.6029119122525304, "STELARA": 0.4033767003656548, "SUTENT": 0.7458464354393349, "SYNAGIS": 2.173370207569456, "TAMIFLU": 3.3078819957721097, "TOZINAMERAN": 0.9985570476712252, "VAXZEVRIA": 1.355469232707954, "XOLAIR": 2.679584000995417, "ZOSTAVAX": 1.025249074336011, "ZYPREXA": 0.7883299411969532, "null": 0.9873353306880172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1797.json
index 7db72a000e5..dce473ee3c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1797.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1797.json
@@ -1 +1 @@
-{"ACLIDINIUM": 20.93627173504365, "ADALIMUMAB": 21.033582186701448, "ALIGN": 187.57056845762975, "AMINOSALICYLIC": 100.3854824212843, "APIXABAN": 2.6851397387148657, "ASPARAGINASE": 13.991273260565896, "AVAMYS": 52.37197552871875, "BUDESONIDE": 112.51583371359511, "COMBIVIR": 8.872108752399962, "CYTARABINE": 3.443327558982505, "ESOMEPRAZOLE": 5.115054897442563, "FLUTICASONE": 10.281796519533245, "MEPOLIZUMAB": 1.9069541693428675, "METHOTREXATE": 6.220702374888782, "NUCALA": 8.771773175649724, "OMALIZUMAB": 2.447115872651612, "PREGABALIN": 31.531845583851723, "ZOSTAVAX": 1.6596500463300157}
\ No newline at end of file
+{"AVAMYS": 3.9545611221506594, "COMIRNATY": 1.4276470915423716, "GARDASIL": 4.574679359891302, "HYDROCORTISONE": 9.094026154220138, "MEKINIST": 3.67200346639987, "SPIKEVAX": 1.1906650492694943, "TOZINAMERAN": 2.6706056867124373, "VAXZEVRIA": 3.336246871383014, "null": 0.4543392680586143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1798.json
index cb7bf486831..b2566602e83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1798.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1798.json
@@ -1 +1 @@
-{"AVAMYS": 19.082042532117885, "BUDESONIDE": 4.5680235817592045, "CICLOSPORIN": 14.607586555487766, "IRON": 54.45556841108845, "OMALIZUMAB": 25.722699476147245, "SPIKEVAX": 1.593910129214296, "TOZINAMERAN": 2.149133624432197, "XOLAIR": 90.44937830054408}
\ No newline at end of file
+{"ABATACEPT": 1.4955857485267503, "ACTRAPID": 0.7173082091574324, "ADALIMUMAB": 0.1335794911103942, "AERIUS": 0.415957714037739, "AFINITOR": 0.2531288940638416, "AIMOVIG": 0.8027454612079027, "ALEMTUZUMAB": 0.5543889670209778, "AMIKACIN": 0.7444889042515147, "AMINOSALICYLIC": 0.1458041941415952, "ARAVA": 1.6526186180189772, "AUBAGIO": 0.0776927141675814, "AVASTIN": 0.1595722412363297, "BEDAQUILINE": 0.2616953986011961, "BENLYSTA": 0.1598372692760298, "BETAFERON": 1.0376401542185505, "BEVACIZUMAB": 0.1744014443079458, "BEXSERO": 2.695787207973562, "BRINTELLIX": 1.0512583890355325, "BYDUREON": 0.1294927070511227, "CASPOFUNGIN": 0.4282874805929635, "CELLCEPT": 0.1888537840370455, "CHAMPIX": 0.0689680512166766, "CHLORHEXIDINE": 1.3052081214120963, "CICLOSPORIN": 0.2600629758618756, "CIMZIA": 1.3692441366378054, "CLOPIDOGREL": 0.2564852913466887, "COMBIVIR": 0.668057672351394, "COMIRNATY": 2.4062381312984398, "COSENTYX": 0.2515441237973139, "COTELLIC": 1.002961250760132, "CYMBALTA": 0.1147109868951336, "CYTARABINE": 0.2997255477065525, "DEXAMETHASONE": 0.4102320901267201, "DOCETAXEL": 0.2627776366563169, "DULOXETINE": 0.1858477375648557, "ELIQUIS": 0.0292005086890723, "ENTYVIO": 0.2101732620023004, "EPIVIR": 0.3647403825996422, "EXJADE": 0.4228825990924952, "FASENRA": 0.613089557215463, "FASLODEX": 0.1334183008300512, "FENTANYL": 0.4566752682845839, "FLEBOGAMMA": 6.951221013208412, "FORSTEO": 0.1523491735467466, "FORXIGA": 0.1457653836733622, "GARDASIL": 0.3486188831576738, "GAZYVARO": 0.8927957404645046, "HERCEPTIN": 0.2520512078984527, "HEXACIMA": 10.32958251899102, "HIZENTRA": 0.260919274068442, "HUMALOG": 0.0579592235758184, "HUMAN": 0.9272713324467392, "HYDROCORTISONE": 0.6191841214918365, "HYQVIA": 1.5332961011868833, "IBRANCE": 0.0701938497473802, "IBUPROFEN": 0.1203451566760113, "INCIVO": 0.2212291956623042, "INFANRIX": 1.0838549217019118, "INSULIN": 0.1019338106599086, "IRBESARTAN": 0.2630421875632593, "JAKAVI": 0.1777850739318854, "JARDIANCE": 0.143275905627964, "KALETRA": 0.1668544017545349, "KEPPRA": 0.1639801760108674, "KESIMPTA": 4.055517813646709, "KEYTRUDA": 0.082090163495428, "KIOVIG": 5.35426907012695, "KYMRIAH": 0.5241486747917408, "LATUDA": 0.1596030707489078, "LEMTRADA": 1.5521251695973122, "LEVETIRACETAM": 0.1113870458438615, "LEVOFLOXACIN": 0.1704558027386769, "LYRICA": 0.1061058878825613, "MEKINIST": 0.8455353827702242, "MENVEO": 0.9055420253274722, "METHOTREXATE": 0.2100439149875646, "MIDAZOLAM": 0.529818302801654, "MMRVAXPRO": 3.589282046461688, "MODERNA": 0.1400938659495773, "NAGLAZYME": 5.537805575717448, "NEULASTA": 0.7070989591884428, "NEXAVAR": 0.1948941807622685, "NIMENRIX": 3.0589154877873166, "NOT": 0.7460945075748551, "OCRELIZUMAB": 0.3436999731783982, "OLANZAPINE": 0.5426689906974796, "OMALIZUMAB": 1.335699420586559, "ONCASPAR": 0.8520589995901348, "OPSUMIT": 0.1846200880647137, "PEGASYS": 0.3240115623894511, "PEGINTRON": 0.1221575397317501, "PLAVIX": 0.0427264278013704, "PLEGRIDY": 1.200189391885503, "PREVENAR": 1.1801843394508078, "PRIVIGEN": 3.78874790369147, "RINVOQ": 0.2097793712696212, "RITUXIMAB": 0.3013554893661044, "ROACTEMRA": 0.1773133641853447, "ROTATEQ": 0.8542890494583993, "SHINGRIX": 1.2578611449775667, "SIMPONI": 0.2433477214526163, "SOLIRIS": 0.2777395634748394, "SPIKEVAX": 2.781323616490092, "SPINRAZA": 0.7886763041291209, "STELARA": 0.1455920773716319, "STIVARGA": 0.1221657576479871, "SUBOXONE": 0.2110736218293613, "SUTENT": 0.1102541657873032, "SYNAGIS": 0.657539765858632, "TAMIFLU": 0.2860477903957888, "TASIGNA": 0.1028477876635447, "TEDUGLUTIDE": 3.919760171494613, "TOZINAMERAN": 0.8302879009591924, "TRACLEER": 0.1279162402727158, "TWINRIX": 0.7971748088410463, "VAXZEVRIA": 4.496812430317139, "VFEND": 0.1172078512552749, "VIAGRA": 0.1075132987450437, "VOTRIENT": 0.0760758076236136, "XELJANZ": 0.1206260866478697, "XOLAIR": 0.3597207553474714, "XTANDI": 0.065759539444169, "ZELBORAF": 0.3870094752761275, "ZOSTAVAX": 0.0797148190229974, "ZYPADHERA": 0.4351306029911434, "ZYPREXA": 0.4153439135732961, "null": 0.2781785802699841}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1799.json
index d05413a1dac..6ea90ced860 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1799.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1799.json
@@ -1 +1 @@
-{"null": 3.0331553627838432}
\ No newline at end of file
+{"VAXZEVRIA": 8.378563935560518}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/18.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/18.json
index c63cf6ef01d..9152205e8d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/18.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/18.json
@@ -1 +1 @@
-{"AFINITOR": 1.062292085872787, "AIMOVIG": 1.4680145417492565, "AVASTIN": 2.0875308007656788, "AZATHIOPRINE": 1.4719877116030011, "BEMFOLA": 79.10508326271024, "BUDESONIDE": 1.0939233765769762, "CICLOSPORIN": 1.2751484229898635, "CLOPIDOGREL": 1.6093382501708575, "COMIRNATY": 2.2912591100450763, "DULOXETINE": 1.0757697528097403, "ELLAONE": 29.46956243178612, "ENOXAPARIN": 2.5522381308127624, "ENTYVIO": 2.6215047175648385, "ESMYA": 9.95289940394091, "ESOMEPRAZOLE": 2.0938787412789925, "GARDASIL": 3.4012786098137373, "GONALF": 8.668791532723365, "IBUPROFEN": 1.082914014256432, "JANUVIA": 1.2837466753030689, "JARDIANCE": 1.8520764994813543, "LONSURF": 1.854581787418916, "LUVERIS": 41.22377280101578, "MAYZENT": 53.635991976801535, "ORGALUTRAN": 23.462033419613583, "OVITRELLE": 28.95095897584982, "SPIKEVAX": 1.1787376822293734, "VAXZEVRIA": 1.1644318980913002, "VICTOZA": 1.4111067670052135}
\ No newline at end of file
+{"LAMIVUDINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/180.json
index d8abb986fa1..3233be37624 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/180.json
@@ -1 +1 @@
-{"CICLOSPORIN": 29.180243734783044, "DEXAMETHASONE": 33.84639287822629}
\ No newline at end of file
+{"ADENURIC": 374.0363049032791, "null": 1.4853375145356105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1800.json
index 1aac1c254bf..2590b822bc5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1800.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1800.json
@@ -1 +1 @@
-{"null": 1.2243969595857331}
\ No newline at end of file
+{"ANAKINRA": 163.86639896139565, "COMIRNATY": 0.2032167110739307, "null": 0.4615949025784387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1801.json
index 52c12600d83..c4b3426e8d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1801.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1801.json
@@ -1 +1 @@
-{"SPRYCEL": 246.4346928007508}
\ No newline at end of file
+{"null": 0.5493432248751642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1802.json
index 045a4a49942..25c6eb2add4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1802.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1802.json
@@ -1 +1 @@
-{"null": 3.4827677595506565}
\ No newline at end of file
+{"null": 0.8325331525086475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1803.json
index 02ff60b0db7..d1913f7f20a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1803.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1803.json
@@ -1 +1 @@
-{"EYLEA": 159.1014628659436, "null": 1.4147254651942618}
\ No newline at end of file
+{"AFINITOR": 6.002953035117815, "ATRIPLA": 0.5056960597519524, "ELIQUIS": 2.2298417226262965, "FASLODEX": 14.065671282392316, "FULVESTRANT": 13.854360592818974, "IBRANCE": 5.624310722418854, "LANTUS": 1.7709260951419692, "SUTENT": 0.7803223297266266, "VOTRIENT": 8.150892251551506, "XELJANZ": 1.367990556328894, "XTANDI": 19.7788821453022, "null": 1.4074925377265202}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1804.json
index 6e8cda535b9..a4662b54d4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1804.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1804.json
@@ -1 +1 @@
-{"GARDASIL": 6.40968737843045, "null": 1.5668314780651218}
\ No newline at end of file
+{"FASLODEX": 49.58146340817728, "null": 0.5764806438393896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1805.json
index 00daa148c31..e21cc61987c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1805.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1805.json
@@ -1 +1 @@
-{"APROVEL": 1.5882063368428192, "BRIDION": 4.7818131768192895, "BUPIVACAINE": 1.2120737781086135, "CASPOFUNGIN": 2.049489649751181, "CLOPIDOGREL": 1.5190988461838857, "COAPROVEL": 1.2456854040199132, "DEXAMETHASONE": 1.105108321078646, "FENTANYL": 3.966666548262004, "GARDASIL": 1.2801961105401505, "GLIBENCLAMIDE": 2.166189922860537, "GLUCAGON": 5.373584282813225, "INCIVO": 1.2119713558329286, "JEVTANA": 2.558965281842434, "LACOSAMIDE": 1.714861911365307, "MELATONIN": 1.2986215694803502, "MICARDIS": 1.6195208152163585, "MIDAZOLAM": 4.2884347708225645, "NOT": 1.069581324447508, "OLANZAPINE": 1.2552157224447396, "PRIVIGEN": 1.1569722248020182, "PROPRANOLOL": 6.763115915249816, "RASILEZ": 2.292286114997746, "RISPERIDONE": 2.420592657576212, "RIVAROXABAN": 3.322376805809953, "SHINGRIX": 1.187400875171312, "SIFROL": 2.080122945048522, "SILDENAFIL": 2.361503825826227, "SUFENTANIL": 15.04516960572782, "TRACLEER": 1.7487631441742872, "TWINRIX": 7.181063100685838, "VFEND": 1.056587221594866, "VIAGRA": 1.8214130575561, "ZOMETA": 3.399830281282492, "ZYPREXA": 1.562458054749009, "null": 2.7545207384561903}
\ No newline at end of file
+{"COMIRNATY": 0.4816487253090576, "null": 0.432947395308572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1806.json
index e5d03603163..bf4375ec269 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1806.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1806.json
@@ -1 +1 @@
-{"null": 5.896547399339858}
\ No newline at end of file
+{"ARAVA": 23.24772682672204, "ATRIPLA": 1.374424265178504, "CICLOSPORIN": 6.859020789322222, "COMIRNATY": 0.1153419888823844, "ENBREL": 9.492195216567929, "STRIBILD": 12.0161605234461, "null": 0.4232126571155947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1807.json
index ed06b7b7db0..9b66f4c70c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1807.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1807.json
@@ -1 +1 @@
-{"JARDIANCE": 106.40946322426382}
\ No newline at end of file
+{"ARAVA": 2.63038578287804, "ATRIPLA": 4.209826967561131, "MACI": 25827.71185109847, "XELJANZ": 6.15747417938938, "null": 0.7136753862183947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1808.json
index 6ab35969eb7..9452b4603ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1808.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1808.json
@@ -1 +1 @@
-{"XOLAIR": 7.747470057477846, "null": 2.3716620455582684}
\ No newline at end of file
+{"ATRIPLA": 74.28981304094967, "KALETRA": 3.98521958879692, "STRIBILD": 39.78471389191874, "TRUVADA": 46.45425171637221, "VIREAD": 19.189644575770068, "null": 0.019468806577043}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1809.json
index 345cc41614a..b558759f6d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1809.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1809.json
@@ -1 +1 @@
-{"COMIRNATY": 2.855414752375806, "SPIKEVAX": 1.0727092548624304}
\ No newline at end of file
+{"ACLASTA": 26.54421966391294, "ANAKINRA": 3.264700050985593, "ARAVA": 1.0309628749513176, "ATRIPLA": 57.33200922846272, "CYMBALTA": 0.9941978894354462, "EVENITY": 84.08274061974352, "FORSTEO": 0.7326692430730082, "KALETRA": 1.3463708515467083, "STRIBILD": 44.9800487963953, "TRUVADA": 41.5219315712452, "VIREAD": 8.572696541278924, "null": 0.0330229511070166}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/181.json
index 700e3e53991..a5912b3fdff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/181.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 181.3710850576448, "ASPARAGINASE": 9.183100393507374, "BASILIXIMAB": 40.59654277619472, "BUDESONIDE": 14.149599972022587, "BUSILVEX": 48.6658719199235, "BUSULFAN": 95.57277397423591, "CELLCEPT": 9.60054174381196, "CICLOSPORIN": 41.71473126444578, "CIDOFOVIR": 178.91709454538486, "CYTARABINE": 11.417995204227672, "DEXAMETHASONE": 4.158450733666188, "FILGRASTIM": 14.02168012438511, "MELPHALAN": 71.32142619791969, "METHOTREXATE": 2.79352658759279, "MYCOPHENOLATE": 19.08039826910249, "RITUXIMAB": 4.6571297170754455, "SOLIRIS": 3.1555051019269347, "SPINRAZA": 11.536564054113493, "SYNAGIS": 22.940543342728503, "THIOTEPA": 53.87190121599772}
\ No newline at end of file
+{"ACLIDINIUM": 9.794300711062869, "APIXABAN": 1.7004004582263894, "ARANESP": 97.06291853551512, "ASPARAGINASE": 3.2819947731632566, "CLOPIDOGREL": 3.4498388054222944, "COMIRNATY": 0.0776997103941332, "CYTARABINE": 3.438429960056684, "ELIQUIS": 3.0149135841013583, "ENOXAPARIN": 15.25670284825008, "ENTRESTO": 2.617762956053923, "EXJADE": 3.5273290095828997, "HEMLIBRA": 72.05148900873449, "KYMRIAH": 11.55304010966129, "LIXIANA": 4.705462149717445, "OLANZAPINE": 0.7997415363569803, "PLAVIX": 2.4321938612491, "PRADAXA": 24.961551686533923, "PRAXBIND": 38.83887178682311, "SPINRAZA": 5.483916253970602, "TOZINAMERAN": 0.2670526629128226, "VAXZEVRIA": 0.5530424833595117, "XARELTO": 12.21657314395192, "ZYPREXA": 0.9591814492400704, "null": 1.507233035427617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1810.json
index a751238d06f..a844dd222e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1810.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1810.json
@@ -1 +1 @@
-{"BYDUREON": 89.40968381714825, "null": 2.060661229853793}
\ No newline at end of file
+{"ABATACEPT": 0.0912764695900123, "ADALIMUMAB": 0.1312837726184611, "ANAKINRA": 1.5396285486701609, "ARAVA": 0.0493097390123496, "ATRIPLA": 78.92080364047796, "BIKTARVY": 0.2873252833745667, "BUDESONIDE": 0.0632180893302891, "CYMBALTA": 0.0238818227671125, "DESCOVY": 2.229346078968495, "ENBREL": 0.0432430246081386, "EVENITY": 1.9410009840378415, "EVISTA": 3.2142303151865432, "FORSTEO": 0.5110017108177084, "GENVOYA": 1.3261129985086386, "HEPSERA": 1.4482363283000208, "HUMALOG": 0.0275604843042065, "KALETRA": 5.300892890983549, "KEPPRA": 0.0216685091147631, "LEFLUNOMIDE": 0.2631751250806767, "LOPINAVIR": 0.8817885573932179, "PROLIA": 0.9588167977792188, "SIMPONI": 0.0381777673238151, "STRIBILD": 41.367314904971614, "TRUVADA": 53.94310226682398, "VIREAD": 17.818182053264678, "null": 0.021797284071067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1811.json
index 1eb8b0f4e6e..7efdf39ac0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1811.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1811.json
@@ -1 +1 @@
-{"AIMOVIG": 1.2771752228778803, "APIDRA": 4.3416142873570704, "BENLYSTA": 42.14962042536585, "BIKTARVY": 12.11422014400143, "BRINTELLIX": 4.739493922506395, "BYDUREON": 28.801118774679463, "BYETTA": 2.481284853379462, "ELIQUIS": 5.050222890493761, "EPCLUSA": 12.398339783711886, "FASLODEX": 2.3056823181092714, "IBRANCE": 1.0134140386825248, "ISENTRESS": 5.293320770679062, "JANUMET": 10.141646726906476, "JANUVIA": 6.323790004703636, "NEULASTA": 2.7403140812014506, "NUCALA": 2.598652114433037, "RELVAR": 15.410906890518753, "XELJANZ": 2.4535527370356784, "null": 2.5577816871447627}
\ No newline at end of file
+{"ABATACEPT": 20.20258202607362, "ADALIMUMAB": 22.67581898634662, "ANAKINRA": 85.05242365733187, "null": 0.3415990878634239}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1812.json
index 46409c9cc2f..fbc21f8a714 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1812.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1812.json
@@ -1 +1 @@
-{"null": 1.1982303864321475}
\ No newline at end of file
+{"null": 2.1931140649392304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1813.json
index 64541bb817c..e6850c5f2b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1813.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1813.json
@@ -1 +1 @@
-{"null": 1.3583110108629803}
\ No newline at end of file
+{"ABRAXANE": 10.893484085997594, "ADALIMUMAB": 0.5211130963837437, "AIMOVIG": 0.415142370063422, "ARAVA": 0.9334990453695003, "ATRIPLA": 28.905640623069985, "AVANDIA": 0.5290666690828768, "AZATHIOPRINE": 1.010035537445004, "BONVIVA": 4.904500151741326, "BYDUREON": 0.6666643945337744, "CICLOSPORIN": 0.3300633949916738, "CIMZIA": 0.8758965963581709, "COMIRNATY": 0.0339859517550905, "COSENTYX": 0.6188663403228492, "CYMBALTA": 0.5482501130454208, "DARZALEX": 1.5183756040725054, "DEXAMETHASONE": 0.6790220218786925, "ELIQUIS": 0.8239337579947108, "EMTRICITABINE": 4.120061661074426, "ENBREL": 1.4659127084928003, "EVENITY": 3.775575725507248, "EVISTA": 4.8123761356662085, "FASLODEX": 1.8529561879500769, "FORSTEO": 3.1646359767512524, "FULVESTRANT": 4.5776373201149605, "GARDASIL": 0.3694425761964707, "HUMALOG": 1.0416355721453878, "HYDROCORTISONE": 2.930371572002754, "IBRANCE": 3.5661787416609565, "INLYTA": 1.0010597026248207, "INSULIN": 0.9127853591125556, "JANUVIA": 1.040702699799619, "JARDIANCE": 0.3006089224346794, "KEPPRA": 0.4621832321632864, "KEYTRUDA": 0.2086771495210082, "LANTUS": 0.4112907379672336, "LYRICA": 1.3649274519334929, "METHOTREXATE": 0.7107980699314601, "PEGASYS": 0.5726471642513008, "RITUXIMAB": 2.181379912924627, "SIMPONI": 0.8988009538582837, "STELARA": 0.4327640820782305, "STRIBILD": 9.567419231356164, "SUTENT": 0.9868444589006338, "TESTOSTERONE": 7.113804647529053, "THALIDOMIDE": 4.40870021513675, "TOZINAMERAN": 0.1517771891078181, "TRUVADA": 13.430547128528756, "VAXZEVRIA": 0.0261736564975258, "VIREAD": 8.314844943384319, "VORICONAZOLE": 1.8442272256760976, "XELJANZ": 3.235393923921121, "XTANDI": 0.7056675998787185, "ZOMETA": 41.80690296883919, "ZOSTAVAX": 1.5817060254037103, "null": 0.5571101808570373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1814.json
index 6b125096b7c..b5de885a89d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1814.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1814.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 522.9912480746402}
\ No newline at end of file
+{"ABACAVIR": 4.959304350083734, "ABATACEPT": 57.39440041919529, "ADALIMUMAB": 19.76485774598445, "AMINOSALICYLIC": 4.016127326760983, "ANAKINRA": 3.987252438724007, "ARAVA": 29.95906977558709, "AZATHIOPRINE": 5.749587006472201, "BOTULINUM": 9.262000062557382, "CELECOXIB": 4.877755447253628, "CELLCEPT": 1.6821942400294505, "CERTOLIZUMAB": 55.72122966408984, "CICLOSPORIN": 3.9007123845144327, "CIMZIA": 2.3923695795306616, "COSENTYX": 4.227226735705486, "ENBREL": 12.29258069706092, "HUMIRA": 1.3891134011823554, "LEFLUNOMIDE": 10.493307234500763, "METHOTREXATE": 1.3815181978716682, "XELJANZ": 1.2716275084670805, "null": 0.079722303129984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1815.json
index 52650941a0a..5f3100e3a5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1815.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1815.json
@@ -1 +1 @@
-{"CHAMPIX": 7.383475853073325, "CYMBALTA": 5.069822067101618, "ZOSTAVAX": 7.873274343145658, "null": 1.2552101158405555}
\ No newline at end of file
+{"FORSTEO": 34.85181838608185, "null": 0.6663820571724743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1816.json
index 8450efa47bb..0d6da5d0fd7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1816.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1816.json
@@ -1 +1 @@
-{"ATRIPLA": 16.9479262962467, "FORSTEO": 4.862508655464087, "HUMIRA": 5.155421744503673, "IBRANCE": 1.48187580262388, "KEPPRA": 2.5179993387763253, "LAMIVUDINE": 12.020634184707609, "LANTUS": 1.8122740308873924, "MELATONIN": 13.657087953362003, "STELARA": 1.506817939701276, "STRIBILD": 11.025723719402247, "TRUVADA": 7.993901502456419, "XTANDI": 1.838358032706908}
\ No newline at end of file
+{"null": 0.6906596195891206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1817.json
index 6f224730cef..9d6290e6d36 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1817.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1817.json
@@ -1 +1 @@
-{"AFINITOR": 10.43651603177777, "ANAKINRA": 17.51310980137076, "AZATHIOPRINE": 85.34361420446479, "CABOMETYX": 21.104395247704208, "CICLOSPORIN": 11.254336318265082, "PAZOPANIB": 376.3078547219088, "SIMPONI": 4.927176858598783, "STELARA": 4.801484228443972, "SUTENT": 9.14123095287988, "VOTRIENT": 28.76355627670105}
\ No newline at end of file
+{"null": 0.6967559409027245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1818.json
index 50401b463e0..0660f18c5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1818.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1818.json
@@ -1 +1 @@
-{"IBUPROFEN": 10.142332201267935, "KEPPRA": 7.465381020256768, "null": 5.703858760757484}
\ No newline at end of file
+{"ATRIPLA": 14.614078007966857, "null": 0.6341789296864849}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1819.json
index dfa04a68687..6f1402daf49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1819.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1819.json
@@ -1 +1 @@
-{"ABILIFY": 5.813513897146685, "DESCOVY": 61.899197137842, "EFAVIRENZ": 41.17202553950213, "IBUPROFEN": 10.523635804757848, "KEPPRA": 12.778271162091464, "null": 3.878848062167914}
\ No newline at end of file
+{"ARAVA": 9.212857541672856, "null": 0.7580837636238139}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/182.json
index 6ef1c23b2de..60dbfd4175f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/182.json
@@ -1 +1 @@
-{"SPIKEVAX": 21.554777269242955}
\ No newline at end of file
+{"LEVOFLOXACIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1820.json
index 2149700bc81..49331912cd4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1820.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1820.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 6.464701926509824, "COMBIVIR": 30.021965792978182, "CYMBALTA": 1.1872660274500697, "IBUPROFEN": 6.91740063532181, "KEPPRA": 8.488709476661263, "LEVETIRACETAM": 3.658521851593559, "SUBOXONE": 2.6079772756504678, "null": 5.674994930699225}
\ No newline at end of file
+{"OFEV": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1821.json
index a010698862e..966638d7581 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1821.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1821.json
@@ -1 +1 @@
-{"null": 9.669067686204542}
\ No newline at end of file
+{"null": 12.339759071923696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1822.json
index 36d359c3245..3905275f78b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1822.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1822.json
@@ -1 +1 @@
-{"null": 1.2750659248573155}
\ No newline at end of file
+{"ENBREL": 28.90035236619756, "null": 1.3319280567229237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1823.json
index d1d30304664..d136a5a0192 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1823.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1823.json
@@ -1 +1 @@
-{"COMIRNATY": 2.7311374751197177}
\ No newline at end of file
+{"ATRIPLA": 9.52679237465253, "null": 0.3490331649683541}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1824.json
index 402a55e7bff..f43b1b96ba3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1824.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1824.json
@@ -1 +1 @@
-{"METHOTREXATE": 16.890677860388443, "null": 5.316568274859348}
\ No newline at end of file
+{"ADALIMUMAB": 0.97459730338982, "AFINITOR": 9.947643234050572, "ALPELISIB": 144.37396459988793, "ARAVA": 0.3614029055382969, "CABOMETYX": 8.066637003611339, "CAPECITABINE": 16.42237096642249, "CARMUSTINE": 62.60948007864048, "CICLOSPORIN": 1.753901724973966, "COMIRNATY": 0.0518316687461856, "COSENTYX": 4.527553107609191, "DENOSUMAB": 105.8441474386898, "DEXAMETHASONE": 7.526358970382487, "DOCETAXEL": 7.042013162264041, "FASLODEX": 18.20638479313589, "FULVESTRANT": 33.432072228914734, "IBRANCE": 4.775696975133128, "JANUMET": 3.963706319567968, "KEYTRUDA": 1.2397333675899058, "KYMRIAH": 14.103931280489345, "NEXAVAR": 1.987461009718897, "RIBOCICLIB": 106.27735925697556, "SUTENT": 2.5302822710511506, "THALIDOMIDE": 21.1461499036955, "XTANDI": 3.5066149558470143, "ZOMETA": 103.63858104400656, "null": 0.404652992097131}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1825.json
index 7094c403fed..9a0f4fb3ff8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1825.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1825.json
@@ -1 +1 @@
-{"APTIVUS": 17988.291258625384}
\ No newline at end of file
+{"ARAVA": 0.020501793753749, "ATRIPLA": 64.02976358464679, "BIKTARVY": 0.4206244063379377, "CELECOXIB": 0.8769996041062896, "DESCOVY": 1.688691060349759, "ENBREL": 0.0610614098361147, "EVENITY": 0.3506589451761864, "GENVOYA": 1.8397868735456655, "IBRANCE": 0.0359782872222646, "KALETRA": 8.444498754134223, "STRIBILD": 44.070120219291205, "TRUVADA": 68.51368227584163, "VIREAD": 15.37925182188718, "null": 0.0114590905519607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1826.json
index 3415a2e6bfc..173bceb4bd6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1826.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1826.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 3.641951468477932, "GARDASIL": 2.81011381527032, "KEPPRA": 2.6584577729989736, "LEVETIRACETAM": 20.53755957175016, "ZYPREXA": 3.15310569170505, "null": 2.655065787714786}
\ No newline at end of file
+{"ARANESP": 5.4838905520951045, "AZACITIDINE": 18.209017773186428, "BEVACIZUMAB": 25.064373326181546, "CARFILZOMIB": 30.565504671558973, "CICLOSPORIN": 1.6874988772683133, "COMIRNATY": 0.0358773957966635, "CYTARABINE": 4.96426837717329, "ELIQUIS": 0.7676020562932951, "EXJADE": 15.083305244680997, "IBRANCE": 2.7868243082948125, "JAKAVI": 4.948869212899512, "KYMRIAH": 11.097710664018605, "NEULASTA": 6.196827253205792, "NPLATE": 34.29551846940135, "OZEMPIC": 92.2849368693547, "PEGASYS": 3.567110032805449, "SOLIRIS": 3.371383080703969, "SPRYCEL": 24.010438561433023, "SUTENT": 0.8254427370224724, "null": 0.6757612766913534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1827.json
index 0af233d98aa..d0c3d1dbb2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1827.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1827.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 5.28961378134356, "CICLOSPORIN": 1.6598191020026205, "CYMBALTA": 2.475582041423069, "DEXAMETHASONE": 1.6639255223696447, "DULOXETINE": 24.144682256803627, "FENTANYL": 14.393011263304532, "GARDASIL": 3.666290331002765, "HYDROCORTISONE": 10.81897970251229, "IBUPROFEN": 8.157182332833603, "IRON": 18.02175576017883, "KEPPRA": 4.078720109040956, "LEVETIRACETAM": 2.4512112549588068, "MIDAZOLAM": 15.327477980575472, "MMRVAXPRO": 1.8641824605176749, "OLANZAPINE": 6.949665684448042, "ZYPREXA": 2.074164085782093, "null": 2.27001975433668}
\ No newline at end of file
+{"ALEMTUZUMAB": 3.546789439691252, "ALIMTA": 20.46912666549953, "ANAKINRA": 2.4220752770464267, "ARANESP": 11.298313397937358, "ARAVA": 0.1808813789032649, "ASPARAGINASE": 11.413029748863606, "AVASTIN": 1.8211410847415055, "AZACITIDINE": 12.053733958989952, "AZATHIOPRINE": 2.8098460404915446, "BASILIXIMAB": 10.24004835820816, "BEVACIZUMAB": 3.1493130140358145, "BLINATUMOMAB": 27.93663564208738, "BLINCYTO": 20.26168879248283, "BUPRENORPHINE": 1.3882676197028525, "BUSILVEX": 38.27667475952431, "BUSULFAN": 18.61035953968596, "CANCIDAS": 4.097566214806905, "CAPECITABINE": 1.815167517748612, "CELLCEPT": 5.511771945516707, "CICLOSPORIN": 4.3416550775647, "CLOFARABINE": 45.64731766443301, "COAPROVEL": 3.4747048564055536, "COMBIVIR": 3.226146820815454, "COMIRNATY": 0.0208407348220313, "CYTARABINE": 16.592443737939597, "DASATINIB": 7.314273040132797, "DEXAMETHASONE": 2.5426234393576865, "DOCETAXEL": 2.0248612367122547, "DOXORUBICIN": 5.579113675177734, "ELTROMBOPAG": 43.85320264691377, "EMEND": 8.81581645064908, "EPOETIN": 17.292079470352064, "EVOLTRA": 54.64760399084529, "EXJADE": 4.626901518625361, "FILGRASTIM": 9.8705142543334, "GANCICLOVIR": 13.67011843057223, "HYCAMTIN": 8.994056512647528, "IBRANCE": 0.4887425022897936, "ICLUSIG": 9.445390356738072, "INCIVO": 6.5768804494509565, "IRINOTECAN": 4.142722585621781, "JAKAVI": 3.018727194949302, "JEVTANA": 6.176863200144685, "KALETRA": 2.829339129371076, "KEPPRA": 1.6737838769997837, "KEYTRUDA": 1.0340878357276664, "KYMRIAH": 6.96689146524679, "MABCAMPATH": 29.362793696680864, "MABTHERA": 12.71043646351251, "MERCAPTOPURINE": 5.523346859949842, "METHOTREXATE": 2.948073556023548, "NILOTINIB": 6.393172293640476, "NPLATE": 2.7653250396083124, "OZEMPIC": 23.666896682547037, "PEGASYS": 2.340701173798871, "PEGINTERFERON": 3.902716244180676, "PEMBROLIZUMAB": 1.6814881764132332, "PEMETREXED": 3.5571300506083587, "PLAVIX": 0.5041757751346513, "RIBAVIRIN": 2.937554684951757, "RITUXIMAB": 3.575576968240346, "SOLIRIS": 7.493755737741591, "SPRYCEL": 4.064937760298294, "SUTENT": 0.9216544792276832, "TASIGNA": 8.898074597962633, "TEMODAL": 75.58261547778442, "TEMOZOLOMIDE": 22.866841213880523, "VENETOCLAX": 5.440158670275344, "VFEND": 1.3830706292836648, "VYXEOS": 72.6453326643622, "XOFIGO": 11.191806673675416, "YESCARTA": 12.491171229720694, "ZYPREXA": 0.396122812349217, "null": 1.0004276226242712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1828.json
index 6cad0e6b114..038fb288ca5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1828.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1828.json
@@ -1 +1 @@
-{"STELARA": 5.705236537077241, "null": 1.9319081740544}
\ No newline at end of file
+{"null": 5.875074040710963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1829.json
index 8ddaa20c8a8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1829.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1829.json
@@ -1 +1 @@
-{"null": 1.319335982684351}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/183.json
index 03b778baaf1..0cb1edc17f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/183.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"COMIRNATY": 0.7884968569757718, "null": 0.6217288389391172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1830.json
index 3b2bc9a3a34..2a2948f33e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1830.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1830.json
@@ -1 +1 @@
-{"CLADRIBINE": 1957.8827723725296}
\ No newline at end of file
+{"XOFIGO": 191.63186198919604, "null": 0.232561476123386}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1831.json
index 389446da105..c609ef30056 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1831.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1831.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 11.969164167580772, "null": 2.798541905095965}
\ No newline at end of file
+{"BUSILVEX": 2456.0126545508742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1832.json
index 6062fb7cd99..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1832.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1832.json
@@ -1 +1 @@
-{"AFINITOR": 1.0589361601253502, "ALEMTUZUMAB": 1.6991315948170156, "AMIKACIN": 19.65318733007692, "ASPARAGINASE": 29.462351886900432, "BLINCYTO": 24.28982063661031, "BUSULFAN": 8.38059916654329, "CARMUSTINE": 11.386443904039048, "CELLCEPT": 1.676153977598137, "CICLOSPORIN": 2.148039959202394, "CUBICIN": 7.431467874360369, "CYTARABINE": 7.351137413831356, "DEXAMETHASONE": 4.556810577087086, "DIFICLIR": 189.13680161789384, "DOXORUBICIN": 2.1838694768949174, "EFAVIRENZ": 7.609831456444077, "ENTYVIO": 1.523714934376546, "ESOMEPRAZOLE": 3.758479670239105, "EXJADE": 1.7021909661521777, "FIDAXOMICIN": 52.24160712664252, "GANCICLOVIR": 4.737792072897808, "INVANZ": 75.26220815004392, "IRINOTECAN": 2.4549686799063744, "JANUVIA": 1.4745268235522475, "KYMRIAH": 5.132989245704502, "LEVOFLOXACIN": 7.428796671954979, "MELPHALAN": 8.944070256971859, "MYCOPHENOLATE": 2.867416718776701, "NOT": 6.956412937382509, "NOXAFIL": 6.237991797570545, "OPSUMIT": 1.7854052366447877, "PANTOPRAZOLE": 1.8116745585174892, "RITUXIMAB": 1.697833325173545, "SOLIRIS": 2.129515562404018, "SPRYCEL": 1.1731887969335315, "SUNITINIB": 13.851988879341262, "TAMIFLU": 1.248812116719031, "TOBRAMYCIN": 7.330993510280246, "TYGACIL": 59.760479895785295, "YESCARTA": 2.965516752817785, "null": 2.883645983708645}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1833.json
index 2e2976370f6..e8720e6ee88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1833.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1833.json
@@ -1 +1 @@
-{"ADEMPAS": 3.517549486517138, "AFINITOR": 1.663738937345206, "ALEMTUZUMAB": 5.1170895895187405, "AMIKACIN": 4.058652063326903, "ASPARAGINASE": 5.586361099615156, "AUBAGIO": 1.2786584943137995, "AZACITIDINE": 4.311910718609019, "AZATHIOPRINE": 4.470428653911436, "BENLYSTA": 1.3809988449595418, "BLINATUMOMAB": 11.4918429646483, "BORTEZOMIB": 5.863781155191644, "BOSULIF": 2.628549378272279, "BUSULFAN": 7.298510760995515, "CELLCEPT": 1.6928089116862677, "CICLOSPORIN": 1.5723382074073535, "CIMZIA": 3.002585580195356, "CLADRIBINE": 6.070420664000085, "CUBICIN": 2.3772193634066983, "CYTARABINE": 5.763065910988553, "DAPTOMYCIN": 7.959074553631679, "DEXAMETHASONE": 1.1365359958945398, "DIFICLIR": 312.5575424723945, "DOCETAXEL": 1.313725728246994, "DOXORUBICIN": 3.1713530572825075, "ENTYVIO": 12.701249913690836, "ERTAPENEM": 36.05915405235726, "ESBRIET": 1.2613139970345078, "EXJADE": 1.0028167100638017, "FASLODEX": 1.0709422713626513, "FIDAXOMICIN": 919.7556850050524, "FILGRASTIM": 9.345076437717816, "HIZENTRA": 3.743072382185313, "HUMIRA": 2.920838904437826, "IBRANCE": 1.4493924361584432, "IBUPROFEN": 2.947251327698933, "INFLECTRA": 16.397941931901922, "INFLIXIMAB": 7.677456660242504, "INVANZ": 24.28068171944017, "IPILIMUMAB": 2.508613837488696, "IRINOTECAN": 2.914459738912785, "LEFLUNOMIDE": 5.549922001958949, "LEVOFLOXACIN": 5.886259591739354, "MELPHALAN": 7.037641393385618, "METHOTREXATE": 1.6802929297288052, "MYCOPHENOLATE": 2.2562725367629133, "NEULASTA": 1.8919123672199023, "OPSUMIT": 3.1238109779995007, "RAPAMUNE": 2.521642374968734, "REMICADE": 3.87603304316962, "REVATIO": 2.1450567238969853, "RINVOQ": 2.665947935295035, "RITUXIMAB": 1.0812326451611864, "SIMPONI": 1.6172044120735758, "SOLIRIS": 3.514460961807502, "SPINRAZA": 2.439469699591208, "SPRYCEL": 2.302652651206349, "STELARA": 6.18318996170692, "TELMISARTAN": 6.492767959112053, "TRACLEER": 1.995069853685904, "VOTRIENT": 1.6647388941320698, "XELJANZ": 4.69433192727976, "XTANDI": 1.5284775582171328, "YESCARTA": 3.146396404017156, "ZINPLAVA": 798.4585521068532, "null": 1.6352803644831753}
\ No newline at end of file
+{"null": 0.3358763809441729}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1834.json
index 1aac1c254bf..8c555a96378 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1834.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1834.json
@@ -1 +1 @@
-{"null": 1.2243969595857331}
\ No newline at end of file
+{"null": 0.8914085045646701}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1835.json
index 5218bf556b4..b99477a7577 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1835.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1835.json
@@ -1 +1 @@
-{"CYTARABINE": 6.583859114937175, "DEXAMETHASONE": 3.279313032348664, "INVANZ": 354.08815233641167, "null": 4.911122106780358}
\ No newline at end of file
+{"ATRIPLA": 1.9400598022608333, "COMIRNATY": 0.7014216719563302, "COSENTYX": 13.254715579195745, "JAKAVI": 9.920524249243169, "PEGASYS": 2.9542107648907314, "SPIKEVAX": 0.4021722834105007, "null": 0.476581045673042}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1836.json
index 9d6ff9253a1..91b0cc715b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1836.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1836.json
@@ -1 +1 @@
-{"ANAKINRA": 169.47928810488636, "PEGASYS": 5.540838200373807}
\ No newline at end of file
+{"CICLOSPORIN": 4.323315020272405, "EXJADE": 109.04897613639268, "ICLUSIG": 40.83326897485544, "NAGLAZYME": 51.802174574825216, "NEULASTA": 24.60955818639396, "NOXAFIL": 41.72220930244511, "SOLIRIS": 23.43464587357212, "SPRYCEL": 57.56143589411527, "VENETOCLAX": 54.07719449791175, "null": 0.4378929280720994}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1837.json
index 6022b6b7d72..6322401c09d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1837.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1837.json
@@ -1 +1 @@
-{"COVID19": 1.0131981938234411, "GARDASIL": 1.8997837268293296, "KEPPRA": 3.167596597194647, "RITUXIMAB": 5.999418821751212, "TELMISARTAN": 44.01255712891343, "TOZINAMERAN": 1.0527878940162014, "null": 1.2662163261555657}
\ No newline at end of file
+{"ALEMTUZUMAB": 58.26015247495518, "BUSULFAN": 39.87594989406452, "CICLOSPORIN": 32.46252021185526, "null": 1.2088221256098302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1838.json
index 1a78429c7d0..f5db46baa04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1838.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1838.json
@@ -1 +1 @@
-{"AIMOVIG": 4.140378339110549, "APIXABAN": 1.4845387839267683, "BUPRENORPHINE": 7.783578870952571, "COVID19": 10.246807404489584, "DEXAMETHASONE": 1.3898710711550848, "SODIUM": 93.0829645908044, "SPIKEVAX": 1.053652549087293, "TOZINAMERAN": 4.667808309579085, "VAXZEVRIA": 1.0639908822591249}
\ No newline at end of file
+{"null": 0.3890390994224157}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1839.json
index 0d6b33f1044..6929bdd0ba5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1839.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1839.json
@@ -1 +1 @@
-{"null": 4.843626274582155}
\ No newline at end of file
+{"ATRIPLA": 6.875806724582245, "HEPSERA": 190.04427165810185, "KALETRA": 92.42925927340475, "null": 0.2743056393640058}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/184.json
index 538500a5fc2..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/184.json
@@ -1 +1 @@
-{"null": 1.1440025403524463}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1840.json
index 719260285b1..63da2b5b74d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1840.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1840.json
@@ -1 +1 @@
-{"APIXABAN": 225.2066524907245, "BUDESONIDE": 90.7661990756028, "ELIQUIS": 15.08833991582244}
\ No newline at end of file
+{"VOTRIENT": 12.676781439013318, "null": 0.8243569658605395}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1841.json
index f1ee0115347..2c7e2976aaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1841.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1841.json
@@ -1 +1 @@
-{"null": 1.8958982074935609}
\ No newline at end of file
+{"null": 1.261034419303237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1842.json
index 65482cd981e..097850f6f26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1842.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1842.json
@@ -1 +1 @@
-{"null": 2.4593523396094774}
\ No newline at end of file
+{"ABRAXANE": 1.2198347457820218, "ACCOFIL": 22.1530615163487, "ACLASTA": 5.057622175263924, "ADEFOVIR": 6.414905892664548, "AFINITOR": 1.3445752566497935, "AIMOVIG": 0.2981052408475512, "AMIKACIN": 0.6030018332396361, "APROVEL": 1.018143447090325, "ARANESP": 0.5782340570201406, "ARAVA": 0.0482833939936003, "ASPARAGINASE": 0.4040766093120156, "ATRIPLA": 1.692572574974341, "AVASTIN": 0.497963903062004, "AXITINIB": 1.1432947944788738, "BENLYSTA": 0.709495284062022, "BEVACIZUMAB": 0.25126784160071, "BIKTARVY": 1.2788459658810236, "BONVIVA": 18.81208898325868, "BORTEZOMIB": 1.6338228529588268, "BOSULIF": 3.1607142444926475, "BRINTELLIX": 0.5680102970807431, "BUDESONIDE": 0.1748549692222919, "BUPRENORPHINE": 0.520937869095261, "BYDUREON": 0.5291582208760406, "CABAZITAXEL": 2.7657154426541912, "CABOMETYX": 0.6485827289428412, "CAELYX": 1.0305341292125672, "CAPECITABINE": 0.8736295250497458, "CARFILZOMIB": 1.633079626539516, "CELLCEPT": 0.2151294697363863, "CHAMPIX": 0.1796430082923988, 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0.919830215979658, "LANTUS": 0.2090146927996317, "LEVOFLOXACIN": 0.2343632130543026, "LONSURF": 0.7905505457265946, "LYNPARZA": 1.760346327289368, "LYRICA": 0.3667668715571104, "MEKINIST": 0.5214550853524956, "MEPOLIZUMAB": 0.2825295427789504, "METHOTREXATE": 0.4902754111909134, "MIMPARA": 3.456732685835604, "MODERNA": 0.6239839106860465, "MOVYMIA": 4.431744975003668, "NEULASTA": 33.27338902052712, "NEXAVAR": 0.227668251308332, "NINLARO": 0.842306013971945, "NIVESTIM": 40.68673118342683, "NPLATE": 1.7691202200315312, "NUCALA": 0.3825022102617529, "OCRELIZUMAB": 0.9347374222114068, "OCTREOTIDE": 4.514649864366543, "OMALIZUMAB": 0.448508184742461, "OPSUMIT": 0.3879583749396457, "OPTIMARK": 2.506116327897064, "PACLITAXEL": 0.9659446867154408, "PEGASYS": 1.4361176497408157, "PEGFILGRASTIM": 26.96172059293343, "PEGINTRON": 1.1371660247052011, "PERJETA": 2.049112437286263, "PLAVIX": 0.1254920009881293, "PLEGRIDY": 1.466705165715145, "PRIVIGEN": 0.4418903667895584, "PROLIA": 2.833537344080409, "PROTELOS": 2.520865924539914, "REBLOZYL": 23.16044402044602, "REVLIMID": 0.7653241241433957, "RIBAVIRIN": 0.4813660958292646, "RIBOCICLIB": 2.2162236238182427, "RINVOQ": 0.2277523657424109, "RITUXIMAB": 0.7914491990508138, "ROACTEMRA": 0.296708447007846, "RUXOLITINIB": 1.977110850932401, "SHINGRIX": 0.7810393949039172, "SIMPONI": 0.4164670889960479, "SOLIRIS": 0.3748236559029184, "SPIKEVAX": 0.9969892644756204, "SPRYCEL": 2.4036667824711304, "STELARA": 0.6966642446596535, "STIVARGA": 0.3207358861290044, "STRIBILD": 1.0455071405969187, "SUBOXONE": 0.5471842243176481, "SUTENT": 1.141595040019863, "TAGRISSO": 0.5239806629096766, "TASIGNA": 2.186145977275645, "TAXOTERE": 1.6599577639022287, "TENOFOVIR": 4.274348497211423, "TERIPARATIDE": 4.1287137660365465, "TERROSA": 6.888177846802693, "TEVAGRASTIM": 27.846789229238368, "TOZINAMERAN": 1.109525799375495, "TRELEGY": 0.3835918556249166, "TREMFYA": 0.3883187892597817, "TRODELVY": 0.830389562441724, "TRUVADA": 1.0835564831225335, "VAXZEVRIA": 2.307711177762891, "VFEND": 0.2650731888853212, "VIREAD": 2.7399374512305257, "VORICONAZOLE": 1.8899045414892464, "VOTRIENT": 0.7580883984836296, "XELJANZ": 1.038421653962517, "XOFIGO": 11.589084110463023, "XOLAIR": 0.954566690769851, "XTANDI": 3.758905539395671, "ZARZIO": 32.51999598045862, "ZOMETA": 3.57574804264202, "ZOSTAVAX": 0.2871017103469915, "null": 0.4361069989182788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1843.json
index 308f06cf1f8..6cc0aea1106 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1843.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1843.json
@@ -1 +1 @@
-{"null": 2.4950645103913405}
\ No newline at end of file
+{"SIMPONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1844.json
index 227413d6cbd..ee0df8fbae3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1844.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1844.json
@@ -1 +1 @@
-{"null": 2.9922010652665}
\ No newline at end of file
+{"null": 0.438944582825541}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1845.json
index f67f3950541..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1845.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1845.json
@@ -1 +1 @@
-{"APIXABAN": 140.54875677027138, "BUDESONIDE": 54.2234253806371}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1846.json
index 7bb7f9f56f3..061fd1dabfe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1846.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1846.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 4.811073366313274, "TRACLEER": 7.406670897859708, "null": 2.113757246688267}
\ No newline at end of file
+{"null": 0.261566081877385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1847.json
index 6102e505302..361f5c23dcb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1847.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1847.json
@@ -1 +1 @@
-{"ANGIOX": 6112.261523717118, "null": 1.0439047684694558}
\ No newline at end of file
+{"ZOMETA": 1451.4647828344212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1848.json
index fccb1724046..066c3a21284 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1848.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1848.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 11.451774500120958, "ENOXAPARIN": 28.40049275492769, "LEVOFLOXACIN": 2.233926540903445, "PLAVIX": 3.3581803388588307, "null": 4.0760177509932}
\ No newline at end of file
+{"ARAVA": 11.271172217124418, "COMIRNATY": 0.4853632202071324, "TOZINAMERAN": 3.4534360275379266, "VAXZEVRIA": 0.2384561333263834, "null": 0.4768376451940261}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1849.json
index e98c6c904a2..9e2e1d7ddfe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1849.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1849.json
@@ -1 +1 @@
-{"null": 1.86520357075331}
\ No newline at end of file
+{"DELAMANID": 211.4616179789929, "GARDASIL": 10.29040971684035, "null": 0.3760337209184556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/185.json
index 937c83bf503..09d7dce8db7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/185.json
@@ -1 +1 @@
-{"ALISKIREN": 818.985859999993, "CHAMPIX": 2.0974310618034138, "ESOMEPRAZOLE": 15.268603145473364, "GARDASIL": 1.3715341898666222, "GLYCOPYRRONIUM": 427.4883404179413, "IRBESARTAN": 11.864618588958349, "KEPPRA": 1.5828760962492383, "ZOSTAVAX": 30.967569271475732}
\ No newline at end of file
+{"CYMBALTA": 8.635840045805667, "LATUDA": 91.89019179892796, "null": 6.2897352553823245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1850.json
index 7446c5cf975..c35f9da125e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1850.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1850.json
@@ -1 +1 @@
-{"ANGIOX": 20.283819701341173, "ARIXTRA": 7.904383536646639, "ASPARAGINASE": 7.293560142298391, "AZATHIOPRINE": 1.0410116113773455, "BLINATUMOMAB": 16.627766824131818, "BRIVARACETAM": 11.621960265885397, "BUSULFAN": 1.97008988070752, "CLOPIDOGREL": 4.430188697001353, "CYTARABINE": 3.193760208366643, "DEXAMETHASONE": 1.6187517409246757, "ELIQUIS": 1.706648405992184, "ENOXAPARIN": 13.743694546364344, "EXJADE": 1.1364402455423697, "EXVIERA": 4.279825938909228, "FENTANYL": 2.2446732471581963, "FILGRASTIM": 2.1561617411715326, "GANCICLOVIR": 2.730106209427165, "IBUPROFEN": 2.2098481279247677, "IRON": 3.50709353019294, "JANUVIA": 1.2810720116118066, "KEPPRA": 1.227205854647492, "KYMRIAH": 18.811886412506823, "LAMIVUDINE": 2.989894582463382, "LEVOFLOXACIN": 3.287296278170556, "LONSURF": 1.366699638496432, "MEKINIST": 1.0014767930941082, "MULTAQ": 2.6557711681417056, "ONCASPAR": 20.76582172902712, "PEGASPARGASE": 15.246538514936956, "PEGASYS": 1.0433053576474374, "PLAVIX": 5.12737158090706, "PRADAXA": 29.09194849269363, "PRAXBIND": 26.50508909634756, "ROACTEMRA": 1.4259267425361175, "SPIRONOLACTONE": 4.447403936477113, "TAMIFLU": 1.3526034444151136, "TIGECYCLINE": 13.385699435208718, "TRACLEER": 1.5209670908743684, "VFEND": 1.2380556655034878, "XARELTO": 13.740802257186036, "YESCARTA": 2.284966711588554, "null": 1.8921355958335544}
\ No newline at end of file
+{"ZOSTAVAX": 34.32020294227965, "null": 1.1602692395733143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1851.json
index 09d23b63cf2..8dc2bd2c243 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1851.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1851.json
@@ -1 +1 @@
-{"KALETRA": 12.568484177670154, "LACOSAMIDE": 26.323474854741374, "null": 7.639110905941137}
\ No newline at end of file
+{"ABILIFY": 14.736889052495949, "GARDASIL": 8.0695702875848, "OLANZAPINE": 11.508896684823007, "SUBOXONE": 17.018454858481338, "null": 1.5878390977837566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1852.json
index 55f922e0aa0..cb33c84357b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1852.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1852.json
@@ -1 +1 @@
-{"null": 2.1632652325959785}
\ No newline at end of file
+{"COMIRNATY": 0.8519785271724762, "VAXZEVRIA": 0.6494479060556768, "null": 0.7581730129060928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1853.json
index 545eff07ae1..04a03e336cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1853.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1853.json
@@ -1 +1 @@
-{"STELARA": 9.334452148806136, "TRELEGY": 38.8707339963184, "XELJANZ": 10.420758902287782}
\ No newline at end of file
+{"COMIRNATY": 1.4216950948839244, "null": 0.2829095297265043}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1854.json
index e91cb49a19f..2d3f21fa7e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1854.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1854.json
@@ -1 +1 @@
-{"AFINITOR": 5.593357305773886, "FORSTEO": 10.42685379391597, "STELARA": 6.045530878668987}
\ No newline at end of file
+{"COMIRNATY": 1.1153556180970474, "null": 0.6409013998259698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1855.json
index 6155c3a27b1..d6a060ab6fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1855.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1855.json
@@ -1 +1 @@
-{"null": 1.9014649402371044}
\ No newline at end of file
+{"MMRVAXPRO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1856.json
index 07f3fccc740..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1856.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1856.json
@@ -1 +1 @@
-{"ABACAVIR": 79.09586377480385, "ADALIMUMAB": 21.00457445841432, "AIMOVIG": 4.915619082930372, "ANAKINRA": 2.747239050458302, "APREMILAST": 15.557613018461916, "ARAVA": 2.782860756321908, "CIMZIA": 2.611479313126323, "ENBREL": 3.1492798545245924, "EXFORGE": 1.1232252787787211, "GARDASIL": 1.716937206047485, "HUMALOG": 1.8374792118255463, "HUMIRA": 2.6707378290782176, "ORENCIA": 19.939869933649923, "PEGINTERFERON": 2.0860795364404403, "RITUXIMAB": 1.5026952690195017, "null": 1.3006589270373417}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1857.json
index ae124614534..24013f78b2f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1857.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1857.json
@@ -1 +1 @@
-{"ABILIFY": 1.578374206301917, "AERIUS": 1.3750933721972365, "AIMOVIG": 1.153047166781901, "ALEMTUZUMAB": 1.1428152826450335, "ALISKIREN": 11.179018053497956, "AMBROXOL": 76.04273014064854, "AMLODIPINE": 63.71014152609484, "ANAKINRA": 1.278479813135422, "APIXABAN": 10.548922457421796, "ARIPIPRAZOLE": 1.280696162570111, "ASPARAGINASE": 1.1303437700760035, "AUBAGIO": 3.965358167748715, "AZILECT": 7.275579916835688, "BETMIGA": 1.1896245130664058, "BIKTARVY": 1.2375912729717713, "BOTULINUM": 1.754893623390504, "BRIVARACETAM": 11.773118964915284, "BRIVIACT": 6.431018476859681, "BUPIVACAINE": 1.1498060057720938, "BUPRENORPHINE": 5.050487804365362, "CAFFEINE": 47.04701700739756, "CANNABIDIOL": 5.429828504700485, "CELECOXIB": 2.27215470601222, "COAPROVEL": 1.181691618011179, "COMTAN": 2.809042268202215, "CYMBALTA": 1.2225212886385235, "DABRAFENIB": 2.78332873890958, "DASATINIB": 2.285508096492271, "DENOSUMAB": 2.8873848975006706, "DULOXETINE": 1.04754105773565, "ENTACAPONE": 5.504113140833774, "ENZALUTAMIDE": 3.4751226011348493, "ESOMEPRAZOLE": 1.4953790901072912, "EXELON": 4.520162761715218, "FAMPYRA": 1.5296662911838603, "FENTANYL": 1.52817106550465, "FYCOMPA": 5.50257768510383, "GARDASIL": 4.309543260610299, "HARVONI": 1.426451894566057, "INTRONA": 2.153039032474172, "KEPPRA": 4.142815939588838, "KYMRIAH": 1.394044021548263, "LACOSAMIDE": 6.854390077970682, "LATUDA": 2.251336355519759, "LEMTRADA": 1.0728732033751638, "LEVETIRACETAM": 5.90983230436221, "LEVODOPA": 4.37768256367095, "LEVOFLOXACIN": 24.327299973212217, "LYRICA": 1.6086876129445111, "MELATONIN": 2.578429730851647, "MEMANTINE": 3.068364178773824, "METFORMIN": 4.855232540577087, "MIDAZOLAM": 1.1171973664402006, "NUCALA": 1.13917289304683, "OLANZAPINE": 3.51444429254314, "PANTOPRAZOLE": 1.4261942331891195, "PEMETREXED": 1.3943019805850607, "PLEGRIDY": 2.0457135058983487, "PREGABALIN": 3.099325484779051, "PROPRANOLOL": 2.561115769944391, "RISPERIDONE": 2.2310978319221086, "SIFROL": 3.0722213782506933, "SPIRONOLACTONE": 3.055447068404584, "STALEVO": 1.59651787524537, "SUFENTANIL": 1.2535913413564828, "TELMISARTAN": 3.492785374209239, "TEMOZOLOMIDE": 1.4570028402013604, "TOVIAZ": 3.928432262636733, "VIMPAT": 4.782300514816201, "XTANDI": 3.513692213241961, "ZYPADHERA": 3.628932009166916, "ZYPREXA": 1.681537079696266, "null": 1.527082583836006}
\ No newline at end of file
+{"ABILIFY": 64.06297781425855, "BUDESONIDE": 41.012281781362304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1858.json
index 3f6c356e7b6..c2ea24e312d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1858.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1858.json
@@ -1 +1 @@
-{"ABILIFY": 4.788458877734608, "ARIPIPRAZOLE": 57.70585410793287, "LATUDA": 19.781820449664394, "OLANZAPINE": 34.11785841693764, "ZYPREXA": 17.53869953576088, "null": 2.2647010133458605}
\ No newline at end of file
+{"ADALIMUMAB": 0.4013979791117504, "AFINITOR": 3.9174066656756494, "AIMOVIG": 3.2432268724035267, "COMIRNATY": 0.1519502875699317, "COSENTYX": 4.891320879776164, "CYMBALTA": 0.9001833704830886, "ELIQUIS": 1.0827330608174042, "ENTYVIO": 6.069815014535119, "GARDASIL": 0.9379916174253348, "HUMIRA": 6.058854449025374, "IBRANCE": 1.302702947325666, "KEPPRA": 1.0823972942266895, "LANTUS": 0.7312379915268541, "PLAVIX": 1.7988136406109898, "SPIKEVAX": 0.1624938261498893, "SUTENT": 1.8953920491701584, "TOZINAMERAN": 1.3247671238793424, "TRULICITY": 3.267803353671958, "VAXZEVRIA": 0.0765713692396426, "XELJANZ": 11.482478671492368, "null": 1.1883698614012466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1859.json
index ff8a30eaa84..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1859.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1859.json
@@ -1 +1 @@
-{"COMIRNATY": 4.74749618218401, "SPIKEVAX": 1.1556619639433146}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/186.json
index 47d69f3b5fc..b588c6bbfd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/186.json
@@ -1 +1 @@
-{"ABACAVIR": 4.237392635996414, "ABATACEPT": 61.32956318748553, "ADALIMUMAB": 48.810600898538105, "AMINOSALICYLIC": 32.407784685791746, "APREMILAST": 113.06969794229198, "ARAVA": 3.5715944422090926, "CERTOLIZUMAB": 47.68692017314798, "CHAMPIX": 2.168077461303479, "COSENTYX": 2.107435768358259, "ENTYVIO": 1.6512502969147569, "MYCOPHENOLATE": 5.500815660546509, "RITUXIMAB": 1.5896935850374745}
\ No newline at end of file
+{"EMTRICITABINE": 193.12131468787092, "TRUVADA": 280.20277738887563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1860.json
index eaf217b7000..78afca2134c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1860.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1860.json
@@ -1 +1 @@
-{"OMALIZUMAB": 120.3782051321448, "null": 1.8820822753636484}
\ No newline at end of file
+{"AZATHIOPRINE": 28.599553121843076, "CELLCEPT": 39.79088570548631, "CICLOSPORIN": 19.62416287592519, "JAKAVI": 62.5039694005586, "MYCOPHENOLATE": 64.15577438979065, "VFEND": 15.418936800221308, "null": 0.3380136731881781}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1861.json
index 80da0a19d01..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1861.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1861.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.6704040336824606, "ACTOS": 3.240249888390692, "ACTRAPHANE": 16.90067023250686, "APIDRA": 6.389651502926942, "BEXSERO": 3.460811840194528, "BUPIVACAINE": 1.3926415542205273, "BUPRENORPHINE": 1.0001577143524196, "CHAMPIX": 1.0722853884862635, "CLOPIDOGREL": 1.37062556875913, "COMIRNATY": 1.4531992531473616, "COVID19": 2.868780119539569, "FLEBOGAMMA": 2.134677419133161, "GARDASIL": 2.122695767082145, "HUMALOG": 1.3483419419474805, "INSULIN": 2.8806103720428613, "LANTUS": 3.240300305767987, "MENVEO": 1.4355991795766163, "NAGLAZYME": 1.0440230943290396, "NIMENRIX": 1.4022211524004224, "NOVORAPID": 1.065710013061303, "SPIKEVAX": 1.683325653004854, "SUBOXONE": 1.988360719600344, "TICAGRELOR": 1.2115514731254986, "TOZINAMERAN": 2.56030530046274, "TWINRIX": 1.2019710851731569}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1862.json
index d77d6ab56b7..e8810aaf282 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1862.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1862.json
@@ -1 +1 @@
-{"COMIRNATY": 2.425283125648158, "METHOTREXATE": 23.91936157796233, "SPIKEVAX": 1.2501671367389613}
\ No newline at end of file
+{"null": 3.997650473907311}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1863.json
index 4de32406b1e..b611c6b2d7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1863.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1863.json
@@ -1 +1 @@
-{"COVID19": 8.141540000771561, "SPIKEVAX": 1.0429131951155568, "TOZINAMERAN": 3.4976507369395096}
\ No newline at end of file
+{"COMIRNATY": 0.8209581537139574, "INSULIN": 26.462402127464188, "SPIKEVAX": 1.3503567714417175, "VAXZEVRIA": 0.3690052201880482, "null": 0.6909284440448334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1864.json
index 93d0f6915e1..678c314f4dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1864.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1864.json
@@ -1 +1 @@
-{"ARZERRA": 120.38516549874858, "CICLOSPORIN": 6.0392319886703385, "CIMZIA": 3.3412561377999723, "ENTYVIO": 54.76873175522815, "HUMIRA": 9.086762356189515, "JANUVIA": 9.436159042095078, "RINVOQ": 17.32529223965676, "ROACTEMRA": 4.268171263404194, "SIMPONI": 11.0886010197495, "STELARA": 17.507295587014674, "XELJANZ": 13.19966951795343, "ZOSTAVAX": 1.7699861904848695}
\ No newline at end of file
+{"COMIRNATY": 0.6366928276599565, "null": 1.4853375145356105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1865.json
index 387937aa441..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1865.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1865.json
@@ -1 +1 @@
-{"null": 1.120368689581554}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1866.json
index b98f5ba6230..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1866.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1866.json
@@ -1 +1 @@
-{"ABRAXANE": 3.2960868771241767, "ADALIMUMAB": 3.715221453936108, "ADCETRIS": 7.604807005373669, "ADCIRCA": 2.3153162566123444, "ALIGN": 52.142493528516816, "ALIMTA": 5.33372639244486, "ALPELISIB": 12.057460787261917, "AMINOSALICYLIC": 27.556620337887317, "ARZERRA": 12.539528052800083, "ASPARAGINASE": 1.3850043358911863, "ATEZOLIZUMAB": 7.358622293728293, "AUBAGIO": 1.0055038188290168, "AVAMYS": 13.987987656743774, "AVASTIN": 1.1564765212861714, "AXITINIB": 3.2702718949425544, "AZACITIDINE": 1.3041288424876551, "AZATHIOPRINE": 9.343537391031086, "BAVENCIO": 3.448389427707756, "BINIMETINIB": 15.530351206102909, "BRAFTOVI": 7.346358293903327, "BUDESONIDE": 19.987251479899147, "CABOMETYX": 2.1689359322287887, "CAPECITABINE": 2.0153161900268204, "CARMUSTINE": 7.993067130491874, "CELLCEPT": 3.379373499537601, "CICLOSPORIN": 1.2892426915906388, "CLOFARABINE": 5.1551841796299085, "COSENTYX": 3.492756924230825, "CYTARABINE": 4.273945618878503, "DABRAFENIB": 2.4084367606706825, "DOCETAXEL": 1.6008777585585598, "DOXORUBICIN": 1.272684608089865, "ENBREL": 1.4188074321628923, "ENTYVIO": 6.307296503352374, "FASENRA": 1.001096703210036, "FIRDAPSE": 1.782116355013122, "GANCICLOVIR": 2.268487688612998, "HIZENTRA": 1.0935056702833412, "HUMIRA": 3.597647153516079, "IBRANCE": 1.0580671341241372, "INFLECTRA": 3.91428327995926, "INFLIXIMAB": 26.41931226093608, "INLYTA": 2.0752499209956072, "IPILIMUMAB": 66.1042328423263, "IRINOTECAN": 3.789579376070665, "JEVTANA": 1.3217348206488138, "KALETRA": 1.0409828581291942, "KEYTRUDA": 13.857553310810966, "LENVIMA": 2.12685117337769, "LIBTAYO": 6.518087400409695, "MELPHALAN": 2.8259187327942668, "NIVOLUMAB": 19.19143562446282, "OFEV": 1.3598933323927846, "OPDIVO": 37.01876210175181, "PACLITAXEL": 2.655044352214303, "PEMBROLIZUMAB": 13.47612884143322, "PIQRAY": 6.025353199249127, "PREGABALIN": 7.974339262640269, "REMICADE": 1.4165398892463588, "RINVOQ": 1.9958817440346188, "ROACTEMRA": 1.8875076819233407, "ROTATEQ": 2.589563341612862, "SAXENDA": 2.0367498075175074, "SIMPONI": 1.5283818156984474, "SPRYCEL": 5.147579309064161, "STALEVO": 1.6032737956008607, "STELARA": 1.8396026757869184, "SUTENT": 1.1333693726091716, "TEMSIROLIMUS": 10.273485339860294, "TOBRAMYCIN": 6.109173088166035, "TRODELVY": 7.717976199434435, "XELJANZ": 1.62702342396301, "XELODA": 2.2421253890274877, "YERVOY": 106.40084007570152}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1867.json
index d50a0628d7d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1867.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1867.json
@@ -1 +1 @@
-{"AIMOVIG": 3.1065727595164567, "ALIMTA": 3.015439272301613, "AVASTIN": 3.261794753444086, "BEVACIZUMAB": 2.152128726708425, "BRAFTOVI": 3.2573631848021267, "BYETTA": 3.4904774463724806, "CELLCEPT": 1.0969690073155478, "CYMBALTA": 1.079218821972488, "ELIQUIS": 1.2257168374687093, "EVISTA": 8.155575366121688, "FORSTEO": 1.362751733756699, "IBUPROFEN": 2.4523218880520417, "INTRONA": 16.695882635023157, "MICARDIS": 2.4768976150401465, "NEXAVAR": 2.6145519494873977, "OLANZAPINE": 4.194947631464654, "PEGASYS": 3.7135905529107336, "PEGINTERFERON": 4.380923873031978, "PEGINTRON": 11.214496666626587, "PLAVIX": 2.405394736046309, "RINVOQ": 2.001933340200184, "SOVALDI": 5.542067546483547, "TAMIFLU": 16.600111831222005, "VICTOZA": 3.451765258297684, "null": 1.7702454289342389}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1868.json
index 8a11ed290df..9d9248a9fa5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1868.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1868.json
@@ -1 +1 @@
-{"AFLIBERCEPT": 116.0068954353034, "ARAVA": 3.3629362434143157, "AUBAGIO": 6.425893920031054, "BUDESONIDE": 7.962968678799189, "CIMZIA": 2.4391187651229056, "CLOPIDOGREL": 1.2164255262957535, "COAPROVEL": 10.291952883887742, "COMTAN": 15.714081148161643, "COSENTYX": 4.077599122346428, "CYMBALTA": 3.81520059694624, "ELIQUIS": 1.327424453100777, "ENTACAPONE": 39.93642886008693, "IBUPROFEN": 2.421737694377692, "KEYTRUDA": 3.859972766733129, "OPDIVO": 5.047996020770578, "PEMBROLIZUMAB": 4.974813588076522, "STALEVO": 29.750259077171357, "null": 1.2080320892344336}
\ No newline at end of file
+{"null": 0.2856277738816383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1869.json
index a8cafa16b9b..7df63bd7069 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1869.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1869.json
@@ -1 +1 @@
-{"ABATACEPT": 3.728922828078847, "ADALIMUMAB": 7.306642473457567, "ALIGN": 54.707103603432806, "AMINOSALICYLIC": 41.42627502497341, "AVAMYS": 14.686878300851731, "AZATHIOPRINE": 9.732036292418076, "BRAFTOVI": 1.7300339846801875, "BUDESONIDE": 21.63333768729744, "CIMZIA": 1.0167511666470714, "COSENTYX": 6.019661948714094, "ENTYVIO": 71.68411751356084, "GANCICLOVIR": 1.5834712441052008, "GOLIMUMAB": 8.373608110345094, "HUMIRA": 11.859736030009048, "HYDROCORTISONE": 2.0136206462918618, "INFLECTRA": 18.59168631025018, "INFLIXIMAB": 43.56200922035162, "IPILIMUMAB": 1.1390490904655457, "KEYTRUDA": 1.1565434740960598, "MERCAPTOPURINE": 2.265380030791519, "METHOTREXATE": 1.707164093779979, "OCRELIZUMAB": 4.479616177531013, "OPDIVO": 1.131892928898068, "PREGABALIN": 8.470413652480138, "REMICADE": 15.757576647736396, "RINVOQ": 7.013436005506558, "SIMPONI": 23.74081199370929, "STELARA": 19.80281446318024, "TREMFYA": 1.009294425738041, "UPADACITINIB": 6.332032557249201, "VEDOLIZUMAB": 30.062009106782423, "XELJANZ": 11.027221022240488, "YERVOY": 4.756232395930666}
\ No newline at end of file
+{"null": 2.3708313970029584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/187.json
index 744d799ea36..dca736694e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/187.json
@@ -1 +1 @@
-{"null": 2.848173647013041}
\ No newline at end of file
+{"ABACAVIR": 4.209149135288143, "BEVACIZUMAB": 9.430101519110217, "COMIRNATY": 0.306016857232319, "NEXAVAR": 3.1720363172057837, "VAXZEVRIA": 0.3362426373118499, "null": 1.2314386081199098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1870.json
index a81cc339d6e..7138d6c085c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1870.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1870.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2798831312705177, "null": 1.384863258856161}
\ No newline at end of file
+{"null": 4.118297318945548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1871.json
index ac4a2490d5f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1871.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1871.json
@@ -1 +1 @@
-{"null": 1.1894899744046088}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1872.json
index ab807d0730d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1872.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1872.json
@@ -1 +1 @@
-{"null": 2.142297341711985}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1873.json
index 990ed6968e2..4839bc8e451 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1873.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1873.json
@@ -1 +1 @@
-{"ARANESP": 1.0709928256039667, "AVASTIN": 4.297730030012303, "BEVACIZUMAB": 3.24419308437258, "BYDUREON": 3.4066561469067125, "BYETTA": 2.788786470719369, "CELLCEPT": 2.538120705690844, "CICLOSPORIN": 1.1002454545978948, "COSENTYX": 1.5742298610123753, "ELIQUIS": 4.291847697780801, "ENTYVIO": 3.0378295529586, "EVENITY": 3.350564067893551, "EXFORGE": 1.457168285703947, "FORSTEO": 2.532868328252632, "FORXIGA": 1.1789860000104624, "HUMALOG": 2.863102979249037, "HUMIRA": 2.2826380856405364, "INCRUSE": 3.6854887227287287, "IRINOTECAN": 2.704008684058976, "JAKAVI": 1.236647179648477, "JANUMET": 1.3716796623965808, "JANUVIA": 2.961843118982559, "JARDIANCE": 1.562886442369662, "LANTUS": 2.6898505623140774, "LEVEMIR": 1.4784401584260398, "LIXIANA": 3.930055850722903, "LONSURF": 7.129126715469529, "LYRICA": 1.085023906379126, "MEKINIST": 2.1869595158399298, "MICARDIS": 4.389582527467555, "NPLATE": 2.439802816128359, "OPSUMIT": 1.368745575943822, "REMICADE": 5.792730116682801, "RINVOQ": 2.843256549723816, "ROACTEMRA": 1.7754318527996935, "SIMPONI": 3.3494678636869915, "SPRYCEL": 1.2922009020457936, "STELARA": 5.552560327019312, "STIVARGA": 63.01735440490184, "TAGRISSO": 1.9461490398863055, "TASIGNA": 1.0746540260580215, "TRACLEER": 1.654461040000627, "TRELEGY": 2.0937096326560045, "TREMFYA": 2.487722162232629, "TRULICITY": 1.6442304465718247, "VECTIBIX": 76.09850701164986, "VIAGRA": 3.565595403451879, "VICTOZA": 2.600259794778375, "XELJANZ": 2.6405366989759216, "XOLAIR": 2.895647900133583, "XTANDI": 1.287646852549858, "ZOSTAVAX": 1.332522741348663, "null": 1.508679726420336}
\ No newline at end of file
+{"BRILIQUE": 7.450364845721653, "BUDESONIDE": 2.037896077226587, "LEVETIRACETAM": 4.518278149119372, "SUTENT": 1.564880357072726, "null": 4.528099149968783}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1874.json
index 2756887560e..65ae5e09764 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1874.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1874.json
@@ -1 +1 @@
-{"AVASTIN": 45.76264673786483, "BEVACIZUMAB": 49.15886405196682, "CAPECITABINE": 18.17424934227769, "IRINOTECAN": 33.925576121019446, "LONSURF": 27.655400712636325, "STIVARGA": 91.76225954538565}
\ No newline at end of file
+{"ABACAVIR": 0.1108812691887188, "ABILIFY": 0.7632504605734476, "ACTOS": 0.8884352813211428, "ADENURIC": 1.2295411977562265, "AERIUS": 0.942723789268545, "AFINITOR": 0.1437605838545635, "AIMOVIG": 0.4149936308966498, "ALEMTUZUMAB": 1.2746125405401685, "ALISKIREN": 1.332126133346946, "AMIKACIN": 0.4021467162298465, "ANAGRELIDE": 7.792058399869827, "ANGIOX": 3.232926801355928, "APIDRA": 0.2399705120685178, "APIXABAN": 0.8840132460663258, "APREMILAST": 0.788472038835624, "APROVEL": 4.701570931250727, "ARANESP": 0.2467018298979608, "ARIPIPRAZOLE": 0.4873427364788559, "ASPARAGINASE": 0.4049155377879651, "ATAZANAVIR": 0.4404658201829384, "AVANDAMET": 0.7495793669620413, "AVANDIA": 0.6130777164066593, "AZATHIOPRINE": 0.2622898278062234, "BEDAQUILINE": 0.4335570090886487, "BETA": 9.180510270570847, "BEVACIZUMAB": 0.2351158043682106, "BEXTRA": 3.406180478568081, "BLINDED": 8.381395270500526, "BORTEZOMIB": 1.6728323760926254, "BRIDION": 38.4081417612463, "BRILIQUE": 5.434465590170487, "BRINTELLIX": 0.3454958992711087, "BUDESONIDE": 0.0700548800541784, "BUMETANIDE": 0.9327050682471448, "BUPIVACAINE": 5.347695545726268, "BUPRENORPHINE": 0.2531232882948199, "BYETTA": 0.2555309217302883, "CANCIDAS": 0.8076448326401555, "CARFILZOMIB": 1.0046408017756203, "CELECOXIB": 0.9362189402917698, "CELLCEPT": 0.3068257986040086, "CERTAGEN": 132.9869017825693, "CHAMPIX": 0.217884999878149, "CICLOSPORIN": 0.0799781262176873, "CLOPIDOGREL": 0.6248515056274615, "COAPROVEL": 4.843167479385705, "COMBIVIR": 1.057202056322472, "COMIRNATY": 0.2299370099323457, "COMTAN": 0.9764549736472832, "COSENTYX": 0.081726545799099, "CUBICIN": 0.7961178626739099, "CYMBALTA": 0.1795066100836899, "CYTARABINE": 0.4787563535409992, "DABIGATRAN": 6.499457051808103, "DACLATASVIR": 3.4923645149869484, "DAKLINZA": 2.142463496181293, "DARZALEX": 0.9588561954120418, "DEXAMETHASONE": 1.693374551847704, "DEXDOR": 62.28032801078921, "DEXMEDETOMIDINE": 21.7285700309672, "DULOXETINE": 0.8100192468125078, "EBIXA": 13.995962881369106, "ELIQUIS": 0.4912039140180524, "EMEND": 0.730893519963096, "EMPAGLIFLOZIN": 2.4947790674104136, "ENOXAPARIN": 0.277044422409411, "ENTRESTO": 1.0236055730197713, "EPCLUSA": 1.5971592161928083, "EPIVIR": 0.6228542531138966, "ESOMEPRAZOLE": 1.166992388742411, "EVENITY": 0.4894490366759398, "EVISTA": 0.3005540936637889, "EXELON": 14.38682618061839, "EXFORGE": 1.4148766692047796, "EXJADE": 0.18006688289953, "EXVIERA": 0.8863620060365845, "FENTANYL": 6.762269644789134, "FESOTERODINE": 20.25370931579716, "FLEBOGAMMA": 0.8799477346670471, "FORSTEO": 0.1061114563597576, "FORXIGA": 0.2848825933640652, "FYCOMPA": 0.8390055917336305, "GARDASIL": 0.4060380744847383, "GAZYVARO": 1.1936155853804074, "GLIBENCLAMIDE": 0.8753830314992529, "GLUCAGON": 11.91358183122607, "HARVONI": 2.106936406079877, "HEMANGIOL": 16.132467294375136, "HUMALOG": 0.0490385279089968, "HUMAN": 0.2783464947094075, "HYDROCHLOROTHIAZIDE": 1.730262354299608, "IBRANCE": 0.040523895721526, "IBUPROFEN": 1.30157886613356, "ICLUSIG": 0.5207222825947387, "INFANRIX": 2.0216463501166184, "INLYTA": 0.2503826285018021, "INSULIN": 0.632715909445685, "INTEGRILIN": 2.885892052627379, "IRBESARTAN": 3.619844977483582, "IRON": 1.226560324222067, "IVABRADINE": 12.921589480449232, "JAKAVI": 0.2345516001676825, "JANUMET": 0.3265306240751681, "JANUVIA": 0.5290569099704175, "JARDIANCE": 0.2367353292958553, "KALETRA": 2.106171559740744, "KARVEZIDE": 4.744682919611394, "KEPPRA": 1.479732250547037, "KEYTRUDA": 0.1643356742051707, "KISQALI": 0.4530249774868384, "KYMRIAH": 0.7084927390013905, "KYPROLIS": 1.376382311588005, "LACOSAMIDE": 2.6395483822902133, "LANTUS": 0.2737525668386389, "LATUDA": 0.8476096241838864, "LEMTRADA": 7.20856554138219, "LEVEMIR": 0.1742602979236067, "LEVETIRACETAM": 1.1564001658752256, "LEVOFLOXACIN": 0.3350310504768557, "LYRICA": 1.254144482816062, "MEKINIST": 0.2296016623655109, "MELATONIN": 0.5246685740036717, "MEMANTINE": 3.785033148374866, "METHOTREXATE": 0.0776665924058944, "MICARDIS": 3.811649158757027, "MIDAZOLAM": 6.082982109077207, "MMRVAXPRO": 0.0930774135851449, "MODERNA": 0.0808773480457053, "MULTAQ": 5.644337114995368, "NEXAVAR": 0.1107360690938931, "NOT": 0.710825930224152, "NOVONORM": 1.488835808745474, "NOXAFIL": 1.937301342560172, "NUCALA": 0.1028491163932132, "OLANZAPINE": 1.5587603329576978, "OLYSIO": 0.5528626435458254, "OPSUMIT": 0.2930570640463222, "PANTOPRAZOLE": 1.0029738330361062, "PAXLOVID": 4.522397380021607, "PEGASYS": 0.0484616140124869, "PEGINTRON": 0.1880960536682593, "PEMBROLIZUMAB": 0.1898843360101413, "PLAVIX": 0.7656748691531257, "PRADAXA": 1.5275415836641917, "PREGABALIN": 1.2639746098101832, "PREVENAR": 0.840065171660601, "PRIVIGEN": 0.9164935997312532, "PROCORALAN": 20.30655186806892, "PROPRANOLOL": 13.22265677960798, "RANEXA": 3.3453749463759723, "RANOLAZINE": 1.2692793382407015, "RAPISCAN": 14.423994458768666, "RASILEZ": 2.404312468317784, "REBETOL": 0.9314458415883388, "REGADENOSON": 15.877287626474516, "REMDESIVIR": 15.23378051477225, "REVATIO": 0.4554981270140613, "REVLIMID": 0.8580102936021342, "RIBAVIRIN": 0.6286325870220634, "RINVOQ": 0.1518898611013532, "RIOCIGUAT": 17.292315872430073, "RITUXIMAB": 0.2127750840071212, "RIVAROXABAN": 2.7422023684968435, "ROACTEMRA": 0.403262145330199, "ROTATEQ": 0.272676813552577, "SAXAGLIPTIN": 11.208551563114597, "SHINGRIX": 0.0948929341708626, "SIFROL": 1.067933219287566, "SILDENAFIL": 3.031167349040817, "SIMPONI": 0.0594032583189384, "SOFOSBUVIR": 8.356390750732139, "SOLIRIS": 0.3231924781865383, "SOMAVERT": 8.070330517226365, "SOVALDI": 1.902732331469016, "SPIKEVAX": 0.1883093285239778, "SPINRAZA": 0.9599309439417036, "SPIRONOLACTONE": 4.585396047739196, "STALEVO": 0.5368559622266252, "STELARA": 0.1203719963875687, "SUBOXONE": 0.2334397268348489, "SUFENTANIL": 6.111009571809047, "SUGAMMADEX": 22.046847964900927, "SUTENT": 0.2712504017961166, "SYCREST": 1.2120548067435213, "SYNAGIS": 2.585727772024736, "TAMIFLU": 0.4844609937537586, "TASIGNA": 0.546174991082662, "TELMISARTAN": 4.090832288773228, "THALIDOMIDE": 4.764114806166199, "TICAGRELOR": 1.298114508031222, "TOVIAZ": 0.3921422953418805, "TOZINAMERAN": 0.2536480586459236, "TRACLEER": 0.5707128104428519, "TRULICITY": 0.1289276823875772, "TWINRIX": 0.5790598409025869, "VALSARTAN": 1.8131907822795432, "VAXZEVRIA": 0.0801353008324601, "VEKLURY": 27.24170596137367, "VFEND": 1.2784679570362922, "VIAGRA": 0.5042730314095574, "VILDAGLIPTIN": 2.725012367964736, "VIMPAT": 6.330814537282234, "VORICONAZOLE": 0.6104958340405977, "VOTRIENT": 0.7126499598716821, "XALKORI": 7.817355391280761, "XARELTO": 1.5108294822147528, "XELJANZ": 0.1818001990513331, "XOLAIR": 0.1998486974072745, "XTANDI": 0.2220279869165094, "XYREM": 1.109141189012526, "YESCARTA": 0.5241420075307184, "ZONISAMIDE": 2.557126501671216, "ZOSTAVAX": 0.1995465057053406, "ZYPADHERA": 1.0278417642852942, "ZYPREXA": 1.2609651175855812, "null": 4.138397467718413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1875.json
index b0f63409a64..79735693c23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1875.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1875.json
@@ -1 +1 @@
-{"STIVARGA": 131.97498990633417}
\ No newline at end of file
+{"BUPIVACAINE": 44.36661248362168, "BUPRENORPHINE": 7.353914601640856, "DEXAMETHASONE": 4.239547821193649, "FENTANYL": 55.204838607142015, "LEVETIRACETAM": 4.348513057783526, "MANNITOL": 120.68706507158598, "MIDAZOLAM": 12.966123567503782, "SUBOXONE": 4.459699629593513, "TRACTOCILE": 236.24926298570804, "null": 2.6356379344361662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1876.json
index 38cd5073adb..c034cc8b4a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1876.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1876.json
@@ -1 +1 @@
-{"null": 2.2246305539333093}
\ No newline at end of file
+{"KEPPRA": 6.760664222956425, "TRACTOCILE": 536.6381484931023, "null": 4.856944356157649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1877.json
index 5bae5b32114..9b92a7aba54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1877.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1877.json
@@ -1 +1 @@
-{"XELJANZ": 14.851118906020046, "null": 1.9512480523136424}
\ No newline at end of file
+{"ABILIFY": 2.263913939166156, "ARIPIPRAZOLE": 4.687434087044972, "AZILECT": 41.09599081372991, "BOTULINUM": 20.55428470215011, "BRINTELLIX": 3.7487171074295382, "CARBIDOPA": 41.0378374359531, "COMIRNATY": 0.3348009671770885, "COMTAN": 24.09326408405268, "CYMBALTA": 0.6621550966379857, "DENOSUMAB": 20.277515825425343, "ENTACAPONE": 56.495550805304994, "HUMALOG": 1.014525987740778, "KEPPRA": 1.9198466633505928, "LANTUS": 1.4576195886680536, "LEVODOPA": 35.247123554883295, "OLANZAPINE": 20.26138502945831, "RISPERIDONE": 16.140439068982165, "SPIKEVAX": 0.300893508052604, "SPIRONOLACTONE": 10.960219120471624, "SYCREST": 44.57062450084656, "TOZINAMERAN": 0.8010559344349584, "VAXZEVRIA": 0.2684973492213364, "XELJANZ": 1.0840120202571044, "YESCARTA": 15.289778675334308, "ZYPREXA": 2.7018454460739987, "null": 1.867822754598425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1878.json
index 4f78bbf7516..731a739207a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1878.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1878.json
@@ -1 +1 @@
-{"ELIQUIS": 4.714050053360888}
\ No newline at end of file
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1879.json
index e69f09908e5..86b66b5385f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1879.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1879.json
@@ -1 +1 @@
-{"null": 1.0719516716239883}
\ No newline at end of file
+{"ABILIFY": 2.2566564083035496, "ARIPIPRAZOLE": 1.4594788277894657, "ATRIPLA": 0.135512494415104, "BRINTELLIX": 2.0977684236123024, "BUPRENORPHINE": 2.195552821611818, "CELECOXIB": 6.6292361675819365, "CHAMPIX": 2.8100834984163345, "COMIRNATY": 0.5651810359492796, "CYMBALTA": 1.7960391007807976, "DULOXETINE": 9.693083264286235, "HUMALOG": 1.2222132636318537, "KEPPRA": 3.945282432521906, "LANTUS": 1.5111541823041634, "LATUDA": 3.042817636044981, "LEVETIRACETAM": 3.5875613242267845, "LYRICA": 2.3001987402126534, "OLANZAPINE": 2.313693262827045, "PEGASYS": 0.600250101731842, "PREGABALIN": 2.9469187098456597, "SPIKEVAX": 0.2555100490441488, "SUTENT": 0.4094788789203151, "TOZINAMERAN": 0.6686085132852263, "VAXZEVRIA": 0.5681836193147523, "YESCARTA": 17.15757591743116, "ZYPADHERA": 5.382589566057559, "ZYPREXA": 2.6534028205758537, "null": 2.2046848471430063}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/188.json
index 5ba2b4d86dc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/188.json
@@ -1 +1 @@
-{"null": 1.0489532232822167}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1880.json
index e437ea8cdea..258d4dd5cfb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1880.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1880.json
@@ -1 +1 @@
-{"ENTYVIO": 25.91822610262592}
\ No newline at end of file
+{"AZACITIDINE": 13.955491513341414, "BENZODIAZEPINE": 24.296804307395703, "BUPRENORPHINE": 10.579026905602571, "COMIRNATY": 0.0220953955686214, "ELIQUIS": 1.1342544897726483, "FENTANYL": 2.175799749237584, "LEVETIRACETAM": 2.3146938810641284, "LYRICA": 4.251876728783902, "MIDAZOLAM": 13.735905012667583, "NALOXONE": 70.86399642644066, "OLANZAPINE": 1.5906548335727844, "PREGABALIN": 27.175871509933792, "SUFENTANIL": 12.13644301079264, "null": 7.38497680331424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1881.json
index ff58caa9170..b9d1cc210d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1881.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1881.json
@@ -1 +1 @@
-{"SUTENT": 7.961687045441544}
\ No newline at end of file
+{"AMIKACIN": 26.55995398593603, "CELLCEPT": 9.942159098670112, "CICLOSPORIN": 16.230360180497456, "COMIRNATY": 0.0505213878701014, "CYTARABINE": 6.997565443782843, "DEXAMETHASONE": 7.204712308273496, "LEVOFLOXACIN": 2.959032855212002, "MYCOPHENOLATE": 16.074020065500108, "PEGASYS": 2.553401724187239, "PEGINTRON": 2.833479219816101, "VORICONAZOLE": 24.318992157061302, "null": 0.7644266672250948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1882.json
index 00b4f831312..e3cb1dd1900 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1882.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1882.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 45.76330366533475, "null": 2.4699264535838386}
\ No newline at end of file
+{"null": 0.982502399410474}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1883.json
index e0cfcdce76c..5cb02de833a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1883.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1883.json
@@ -1 +1 @@
-{"INCRUSE": 68.13562467156547, "JANUVIA": 10.525422215393371, "ZOSTAVAX": 35.99695135219424, "null": 1.3629131392705724}
\ No newline at end of file
+{"COMIRNATY": 0.4603714934862112, "null": 0.7668983925861758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1884.json
index 2b522f7d13c..d82d9fb5484 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1884.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1884.json
@@ -1 +1 @@
-{"null": 3.5070305741311985}
\ No newline at end of file
+{"COMIRNATY": 0.2225992189887166, "ELIQUIS": 10.5768407859571, "VAXZEVRIA": 0.5555240462133356, "null": 1.1582564496851282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1885.json
index 9a92c5688e3..4da066f55fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1885.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1885.json
@@ -1 +1 @@
-{"null": 6.569142317722045}
\ No newline at end of file
+{"CLOPIDOGREL": 1.600285617609941, "COMIRNATY": 0.1666019016632419, "CYMBALTA": 1.3590158843743598, "DULOXETINE": 17.72281390987343, "EPIVIR": 15.313579017993831, "FENTANYL": 4.543459781135089, "IBUPROFEN": 5.066412453155303, "KEPPRA": 1.4731908966313634, "MIDAZOLAM": 13.218121263197473, "NALOXONE": 68.56268387164482, "NOVOSEVEN": 25.612816933672114, "OLANZAPINE": 3.1652462740976923, "SOLIRIS": 4.2979058698090045, "SPIKEVAX": 0.1238183368406398, "SPINRAZA": 11.070390026079266, "TAMIFLU": 4.459372039558303, "VAXZEVRIA": 0.3117389483674601, "ZYPREXA": 2.70301258780795, "null": 1.7202040530083482}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1886.json
index 6bf917756fd..24ccc12a9dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1886.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1886.json
@@ -1 +1 @@
-{"BYETTA": 20.822940479109377, "CHLORMETHINE": 711.9590742088476, "JANUMET": 10.51235184839325, "JANUVIA": 6.694468535768031, "STELARA": 4.349670037640452, "ZOSTAVAX": 11.036312597761317, "null": 1.7149580837711589}
\ No newline at end of file
+{"ABILIFY": 0.7243196683922176, "AIMOVIG": 3.268385299087306, "ATRIPLA": 0.0919242935634694, "AUBAGIO": 1.2747710585803338, "BENLYSTA": 2.1332784180768622, "BIKTARVY": 0.7344404884772338, "BORTEZOMIB": 3.80838561950461, "BOSULIF": 3.43538619487984, "BRAFTOVI": 1.871113201662488, "BRINTELLIX": 1.0355378578517231, "CARFILZOMIB": 2.363486417080244, "CELECOXIB": 1.2140065027761149, "CELLCEPT": 0.3776280320871487, "CHAMPIX": 0.3679040145942702, "CIMZIA": 0.3473051298932676, "COMIRNATY": 1.8737713280370116, "COSENTYX": 0.1852101673758258, "CYMBALTA": 1.5917762011651957, "DEXAMETHASONE": 0.2591389665572626, "DULOXETINE": 1.6749749346227296, "ELIQUIS": 0.4419705603601871, "ENTYVIO": 1.5254432170229415, "FAMPYRA": 0.8168406127279666, "FASLODEX": 0.5672580641934682, "FIRDAPSE": 1.9889724147795456, "GARDASIL": 1.707249315118888, "HARVONI": 1.7183451309681066, "HIZENTRA": 1.1095186885424742, "HUMALOG": 0.2852270279512593, "HUMIRA": 0.3914713568272852, "HYDROCORTISONE": 0.9684477386526494, "IBRANCE": 3.014351312471477, "IBUPROFEN": 0.5116746393477778, "INLYTA": 0.7300868217212524, "IRON": 2.779377747333277, "JARDIANCE": 0.4768369589771605, "KAFTRIO": 4.231525151537546, "KEPPRA": 0.5368777121168647, "KESIMPTA": 2.0216948139048894, "KEYTRUDA": 0.2413698347070845, "LANTUS": 0.1414065413252783, "LATUDA": 0.7682032154970517, "LEVOFLOXACIN": 0.3399853177384475, "LYRICA": 0.9071377511697414, "METHOTREXATE": 0.7715517906016108, "NEULASTA": 1.2009777139717626, "OCRELIZUMAB": 2.921247072799072, "OPTIMARK": 0.6932493743097792, "PEGASYS": 1.1963797860857557, "PEGINTRON": 0.5471051510525924, "RUBRACA": 1.5715213449794023, "SHINGRIX": 0.7427374394637012, "SIMPONI": 0.2628380602635725, "SOLIRIS": 0.3882915229392946, "SPIKEVAX": 1.5192530126325965, "SPRYCEL": 0.665865490115203, "STELARA": 0.7732869713157775, "SUTENT": 0.3628527534299829, "TEDUGLUTIDE": 23.39382677643475, "TOZINAMERAN": 6.562658577159108, "TRULICITY": 0.6942032462188663, "VAXZEVRIA": 1.3889153779998933, "VOTRIENT": 0.3661675892314551, "XELJANZ": 1.1009030911782869, "XTANDI": 0.6289478264981727, "XYREM": 2.345878159167349, "ZOSTAVAX": 0.1859749646909497, "null": 0.5671063973177372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1887.json
index e3a40aba8e5..695f41b0dea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1887.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1887.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 1.5428182535799913, "STIVARGA": 20.789843672744063, "VALSARTAN": 2.0160414758573206, "null": 38.24214475571569}
\ No newline at end of file
+{"BRILIQUE": 11.374993809387217, "BUDESONIDE": 2.1810019241330987, "BUPIVACAINE": 11.880294347755784, "CELLCEPT": 5.01506800087939, "CICLOSPORIN": 3.244009854243183, "CLOPIDOGREL": 10.440052970334332, "COMBIVIR": 20.24134123754979, "COMIRNATY": 0.162157513385059, "CYMBALTA": 2.6539025647792114, "DEXAMETHASONE": 2.925831862630325, "ELIQUIS": 4.36478182735393, "ENOXAPARIN": 12.233605705415815, "FENTANYL": 2.626890160234759, "PLAVIX": 4.35279931755304, "SOLIRIS": 3.416566970038664, "SPIKEVAX": 0.1115431501597841, "VAXZEVRIA": 0.1956904175992388, "null": 1.0833038337908747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1888.json
index 7722a41424d..02c280e43bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1888.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1888.json
@@ -1 +1 @@
-{"AFLIBERCEPT": 255.97948715640288, "AVASTIN": 35.99606509494143, "BEVACIZUMAB": 122.36531925249588, "CAPECITABINE": 16.005697177598748, "IRINOTECAN": 84.34960623697118, "LONSURF": 31.77209285306245, "PANITUMUMAB": 179.06056635253694, "REGORAFENIB": 397.3651147397352, "STIVARGA": 409.7156699371501, "VECTIBIX": 188.6553068742261}
\ No newline at end of file
+{"COMIRNATY": 0.1692252617031102, "PEGASYS": 2.0026783142203635, "null": 1.820103029395369}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1889.json
index c22a007c094..747ac361fec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1889.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1889.json
@@ -1 +1 @@
-{"STIVARGA": 325.45601586150894}
\ No newline at end of file
+{"ABILIFY": 1.336228533383063, "AIMOVIG": 2.139986712000542, "AVANDIA": 3.917724158352318, "BUPRENORPHINE": 7.692569653824715, "CHAMPIX": 0.4233788825238555, "CICLOSPORIN": 0.4715670207913131, "COMIRNATY": 0.1337425109167094, "CYMBALTA": 1.7273265344287545, "DOXORUBICIN": 2.690599529770381, "DULOXETINE": 4.321454254520612, "ELIQUIS": 0.7092400738049967, "FENTANYL": 4.668374875120036, "FESOTERODINE": 172.84067716290758, "GARDASIL": 0.7081990511662986, "HUMALOG": 3.5958092061689064, "IBRANCE": 0.4353631473097942, "IBUPROFEN": 3.330092388874432, "INSULIN": 1.432909094000747, "JARDIANCE": 1.4837478477231782, "KEPPRA": 3.659589083540871, "LANTUS": 1.981231387995198, "LATUDA": 3.477766499593059, "LYRICA": 2.3337403747797683, "MIDAZOLAM": 3.784990756836197, "NALOXONE": 28.36220972493608, "NOVOSEVEN": 6.294831099992516, "OLANZAPINE": 3.004699438710137, "PEGASYS": 0.2650184386416825, "PLAVIX": 1.285997522438521, "PREGABALIN": 6.064269605999365, "PROPRANOLOL": 12.277419175542196, "RISPERIDONE": 6.020931689875798, "SOLIRIS": 0.8324225460891194, "SPIKEVAX": 0.1164595861507994, "SPINRAZA": 8.162099182819983, "SUBOXONE": 5.360006017786394, "SUTENT": 0.1820350259290205, "TAMIFLU": 1.0959725044804276, "TOZINAMERAN": 0.6200415690281339, "TREMFYA": 2.1956455292758643, "VAXZEVRIA": 0.2444576388575894, "VIAGRA": 5.539057401403409, "XELJANZ": 0.3191273651771967, "XOLAIR": 0.9390496132614043, "ZYPREXA": 2.427785694793206, "null": 2.1401602925175003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/189.json
index 099bb6f75af..806e1ecd8c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/189.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9493976390910384, "FORSTEO": 39.98048944320949, "SIMPONI": 12.788536084676805}
\ No newline at end of file
+{"COMIRNATY": 3.3698833186622426}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1890.json
index 3ec564bb072..27d1cecd8f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1890.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1890.json
@@ -1 +1 @@
-{"null": 5.992219891988702}
\ No newline at end of file
+{"INTUNIV": 13984.089535116078, "KEPPRA": 75.90318793611925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1891.json
index 8b47102e7a0..2afbc0c4bf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1891.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1891.json
@@ -1 +1 @@
-{"null": 8.713709740761487}
\ No newline at end of file
+{"KEPPRA": 12.297721493526062, "null": 1.812672104228349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1892.json
index 651b433e9f1..c95aeafcc97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1892.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1892.json
@@ -1 +1 @@
-{"null": 4.483532431141876}
\ No newline at end of file
+{"ENTRESTO": 31.065263152780187, "IRBESARTAN": 169.5080842160149, "null": 0.7840096321632034}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1893.json
index 05d186343fb..de33cf8e420 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1893.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1893.json
@@ -1 +1 @@
-{"STIVARGA": 94.30195652008835, "null": 2.449885637549513}
\ No newline at end of file
+{"null": 1.2678387061803291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1894.json
index 512d86629af..ffa605fe509 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1894.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1894.json
@@ -1 +1 @@
-{"CIMZIA": 7.060240194721985, "STELARA": 5.436819374679723, "XELJANZ": 4.496799654131503, "null": 1.1499546880948672}
\ No newline at end of file
+{"ADCIRCA": 35.71120497221266, "ADEMPAS": 18.55263830961768, "AMBRISENTAN": 25.95471323723197, "CHOLESTAGEL": 273.17683769580447, "CICLOSPORIN": 1.095136833782225, "CLOPIDOGREL": 1.1573930519882671, "COMIRNATY": 0.3519940894758678, "ELIQUIS": 0.8015221059813635, "ENTRESTO": 22.80125123847497, "EXJADE": 2.286815481654695, "JANUVIA": 3.127585634251673, "JARDIANCE": 1.263707082286059, "KEYTRUDA": 2.2493072929339464, "KYPROLIS": 23.84739247449997, "LANTUS": 1.3166623116193106, "MULTAQ": 17.529504878493565, "OPSUMIT": 18.8190142438238, "RASILEZ": 10.385910757321168, "RIVAROXABAN": 30.440916811142237, "SPIKEVAX": 0.2901836689546047, "TASIGNA": 3.122998259446893, "TOZINAMERAN": 0.2191303405183297, "TRACLEER": 7.935174741042364, "null": 1.161832735762461}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1895.json
index f2bff6c496b..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1895.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1895.json
@@ -1 +1 @@
-{"AIMOVIG": 9.897907229596813, "LANTUS": 2.510433966817682, "VFEND": 88.04781897278984, "VIAGRA": 13.773448885603768}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1896.json
index a58b8b1c344..bca8d94fa81 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1896.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1896.json
@@ -1 +1 @@
-{"null": 2.0732840918983566}
\ No newline at end of file
+{"AFINITOR": 4.158905596908886, "AIMOVIG": 1.6327722006858068, "AUBAGIO": 1.6260402836371532, "BRAFTOVI": 7.443312610076406, "CELLCEPT": 1.6617111619488405, "CHAMPIX": 0.8774535442466974, "CICLOSPORIN": 0.6084824261491538, "COMIRNATY": 0.1181602068285945, "CYMBALTA": 0.5991028378822612, "ELIQUIS": 1.7681103830896407, "ENBREL": 0.9537458330517504, "ESBRIET": 2.075616677912593, "EXFORGE": 2.382019310003202, "FAMPYRA": 3.6720205085672193, "FORSTEO": 1.7427136560887455, "HUMALOG": 3.751584020368247, "IBRANCE": 0.8669940951409301, "IRESSA": 4.505140404453085, "JANUMET": 1.375129108751959, "JARDIANCE": 0.7021438181675376, "KEPPRA": 10.138056478812556, "KEYTRUDA": 1.1733362872606925, "LANTUS": 2.466746429833496, "MEKINIST": 11.370685293800545, "NEXAVAR": 0.7813928998942781, "SOMATROPIN": 32.95469153570535, "SPIKEVAX": 0.0772207394477635, "STELARA": 1.1969136967891478, "SUBOXONE": 1.2254177337123473, "SUTENT": 0.8497043277422858, "TAGRISSO": 6.644883522038496, "TOZINAMERAN": 0.1658562686122669, "TRELEGY": 3.277012078842939, "TRULICITY": 2.265434111126974, "VAXZEVRIA": 0.0733017444035008, "VIMPAT": 10.307494621460648, "VOTRIENT": 6.669036259736003, "XELJANZ": 1.0276061640670873, "XOLAIR": 1.902238067866885, "XTANDI": 1.78922011029047, "ZELBORAF": 10.077720484121896, "null": 1.577255470802466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1897.json
index 72b1b570d2f..34609a01eb2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1897.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1897.json
@@ -1 +1 @@
-{"ABILIFY": 2.072918949795687, "ACIDOPHYLUS": 189.14256591198043, "ACTOS": 1.5143069973906087, "ACTRAPID": 2.5153928242969834, "ADENURIC": 1.5924627991124505, "ALL": 2.2575438490669297, "APROVEL": 2.5076808234509627, "ARIXTRA": 2.305248203011274, "AZTREONAM": 3.954640347295145, "BENZODIAZEPINE": 10.88343757801302, "BEVACIZUMAB": 1.1529743748740244, "BRILIQUE": 1.9555253200481597, "BRIVIACT": 1.1069710572582512, "BUPIVACAINE": 1.3082732653833329, "BUPRENORPHINE": 3.020476739536321, "CASPOFUNGIN": 1.7786820443268128, "CELLCEPT": 3.478121286310658, "COAPROVEL": 1.052423267154742, "COMTAN": 3.6829835114493887, "CYMBALTA": 1.6020212338701412, "DESLORATADINE": 1.9679245420246367, "DEXAMETHASONE": 1.0033998881876856, "DULOXETINE": 7.237935322015623, "EBIXA": 2.5440764636835174, "EMEND": 1.1769162080793465, "ESOMEPRAZOLE": 1.4504783968127002, "EUCREAS": 2.111216858542408, "EXFORGE": 1.042476712163192, "FENTANYL": 2.759728625273288, "FYCOMPA": 1.1932289733688766, "GALVUS": 1.8655776140088864, "GLIBENCLAMIDE": 3.787670881894487, "GLUCAGON": 3.0211698752762173, "HUMALOG": 2.470026658115763, "HYDROCORTISONE": 1.531830754193376, "IBUPROFEN": 3.6888094389882102, "INSULIN": 1.1499993152590076, "INVOKANA": 1.2073075009084224, "IRBESARTAN": 1.9168688418697937, "ISENTRESS": 2.278509604914939, "KALETRA": 1.4259934712024065, "KEPPRA": 2.6706483891023045, "LACOSAMIDE": 1.006931405471423, "LANTUS": 1.8406151175407224, "LEVEMIR": 1.5092803664977965, "LEVETIRACETAM": 1.6459735853287512, "LOXAPINE": 8.690055686184495, "LYRICA": 4.782693282333893, "MIDAZOLAM": 6.380361981717264, "MIXTARD": 3.123999946806339, "NALOXONE": 3.5808030444649783, "NORVIR": 1.4050636838040038, "NOVONORM": 1.5954285139018485, "NOVORAPID": 1.277439293488723, "NOVOSEVEN": 1.0558944926897085, "OLANZAPINE": 5.460787019478733, "PANTOPRAZOLE": 1.5667786331994873, "PLAVIX": 1.392028055103338, "POPPERS": 7.324679340334201, "PREGABALIN": 9.480153993379984, "PROPRANOLOL": 2.737417437053067, "RISPERIDONE": 1.5660295547947944, "SIFROL": 1.878216271212637, "SODIUM": 7.077070081568211, "STALEVO": 1.324961407121777, "SUBOXONE": 1.090523590436867, "SUFENTANIL": 2.6877120496775144, "TEMODAL": 1.0672829466678928, "TRICYCLIC": 26.76009390116617, "VALDOXAN": 5.05407652742842, "VFEND": 1.4380122594112488, "VIAGRA": 1.1067564540721708, "VILDAGLIPTIN": 5.755527578245456, "VIMPAT": 1.480948428770349, "XARELTO": 1.337934203316898, "XYREM": 2.4178254001898605, "ZYPADHERA": 5.448804033078474, "ZYPREXA": 5.732816550082031, "null": 3.829866379483963}
\ No newline at end of file
+{"HUMALOG": 13.16960319931762, "null": 1.3634391091333595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1898.json
index 120326792df..986353d90a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1898.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1898.json
@@ -1 +1 @@
-{"JARDIANCE": 39.398991553231255, "null": 1.35440634945964}
\ No newline at end of file
+{"ELIQUIS": 2.788128476706056, "KEPPRA": 2.18670568250981, "LANTUS": 2.4748088912394333, "MEKINIST": 10.104658395365847, "TRELEGY": 13.7331505587741, "VOTRIENT": 3.735062733615496, "null": 3.441020168751717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1899.json
index 1c1a499de30..873a7c17129 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1899.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1899.json
@@ -1 +1 @@
-{"ASPARAGINASE": 16.583530976311824, "NEXAVAR": 24.850311588862976, "PEGASYS": 2.1299743612146083, "STIVARGA": 9.135235659397043, "SUTENT": 2.4197168042214634, "null": 1.922663175655666}
\ No newline at end of file
+{"ABACAVIR": 0.6056280023421041, "ASPARAGINASE": 2.65165890841649, "AVASTIN": 3.682813638203828, "BEDAQUILINE": 7.484980463666909, "BENZODIAZEPINE": 11.160649193841117, "BORTEZOMIB": 5.656948749195101, "BRAFTOVI": 3.029499074691308, "BUDESONIDE": 0.6085300921083439, "BUPRENORPHINE": 6.37688093377228, "CAELYX": 2.2878285002293035, "CAPECITABINE": 1.5182364819091758, "CELLCEPT": 1.5062080480586604, "CICLOSPORIN": 5.216079472016175, "CLOPIDOGREL": 1.7122563659655077, "COMIRNATY": 0.1459644179106473, "CYMBALTA": 0.8882153186350825, "CYTARABINE": 1.8699194645293984, "DEXAMETHASONE": 5.052341814905205, "DOXORUBICIN": 4.177056157644085, "ELIQUIS": 0.6482486130747576, "ENOXAPARIN": 1.812085705549625, "EXJADE": 0.599508048743015, "FENTANYL": 2.319920533547432, "FILGRASTIM": 3.664707415618436, "GARDASIL": 0.4071841586571426, "HUMALOG": 0.7971992202626532, "IBRANCE": 0.5979878408399479, "IBUPROFEN": 3.635715323157788, "INLYTA": 3.067305344091216, "IRESSA": 2.976459914054294, "JARDIANCE": 0.8938716023634, "KEPPRA": 2.9549201986966933, "KEYTRUDA": 2.31691538115578, "KYMRIAH": 3.950546775118291, "LANTUS": 0.6226667617531146, "LEVETIRACETAM": 1.5183280719892644, "LEVOFLOXACIN": 0.8922579940955014, "LYRICA": 0.8449147366330653, "MANNITOL": 20.95745080810684, "MEKINIST": 2.9481378578518056, "MIDAZOLAM": 6.964735946214777, "NAGLAZYME": 2.815338211238017, "NALOXONE": 27.452836616213578, "NEXAVAR": 0.5685540782448673, "NOXAFIL": 3.990498097432586, "OLANZAPINE": 2.376212097939089, "OPDIVO": 2.2233192991500506, "PEGINTERFERON": 1.1195788360684629, "PEGINTRON": 0.5756826243441135, "PLAVIX": 0.6777351020964747, "SOLIRIS": 2.6122143898852146, "SPIKEVAX": 0.1555738271790127, "STELARA": 0.35024036843057, "SUBOXONE": 0.9309995228053618, "SUTENT": 0.9965189442580809, "TAGRISSO": 3.1302435548088, "TAMIFLU": 0.8455144663001964, "TEMODAL": 14.227845757049147, "TEMOZOLOMIDE": 9.21045529819666, "TOZINAMERAN": 0.4938381430450448, "VAXZEVRIA": 0.2121283553017545, "VFEND": 1.1567437198968027, "VOTRIENT": 1.9983747828401208, "XTANDI": 0.4623483925642089, "YESCARTA": 8.70466275827124, "ZYPREXA": 1.5546621140018415, "null": 1.8441801235015156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/19.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/19.json
index b4b1e321543..db8ee580eed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/19.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/19.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.004506008776299, "ABATACEPT": 3.767436368640949, "ACE": 2.644528394223161, "ACETYLSALICYLIC": 8.813337145569657, "ADALIMUMAB": 3.411225519294096, "ADEMPAS": 1.897818868975455, "AERIUS": 1.5474724710567695, "AGOMELATINE": 1.8205460900497268, "AIMOVIG": 2.793266605371511, "AMBRISENTAN": 1.0859135778932798, "AMINOSALICYLIC": 1.685580635508192, "ANTIBIOTICS": 1.2174003840582386, "APIXABAN": 2.786301084984288, "APREMILAST": 1.7412742901725404, "ARAVA": 1.8692863488359124, "AUBAGIO": 1.2165250178033762, "BARACLUDE": 1.1307118922829362, "BETMIGA": 1.522827963685065, "BONVIVA": 2.576036982290252, "BOSULIF": 1.866093393559503, "BRILIQUE": 1.120385533797778, "BRINTELLIX": 2.032781047349109, "BYDUREON": 1.6033179332936105, "BYETTA": 1.4526811427584156, "CELECOXIB": 2.825999186704578, "CERTOLIZUMAB": 1.742801694187094, "CHAMPIX": 1.6663531061072954, "CIMZIA": 1.0293287259698367, "CIRCADIN": 1.77597893142665, "CLOPIDOGREL": 2.075140331279083, "COAPROVEL": 1.2854391649151478, "COVID19": 1.4362115945258844, "DAKLINZA": 1.9584466336805129, "DASSELTA": 7.91321796122384, "DENOSUMAB": 1.1262315326933228, "DIFICLIR": 1.2584416343212568, "DULAGLUTIDE": 1.0334947061612776, "ELLAONE": 3.0368345967082138, "ENBREL": 1.5964736126480896, "ENTYVIO": 1.2596540730350994, "EPCLUSA": 1.3051449861079747, "ESBRIET": 2.5936633399688853, "ESMYA": 1.1379515759836407, "ESOMEPRAZOLE": 1.212112354831602, "EUCREAS": 3.803817952370124, "EXJADE": 1.976516110270864, "EXVIERA": 1.4360324716808794, "FAMPYRA": 1.4169823724306831, "FIRDAPSE": 2.1604485574137917, "FORSTEO": 1.9515459744154096, "FORXIGA": 1.09580574940356, "GALAFOLD": 1.930771979037217, "GALVUS": 2.3898946325210093, "GARDASIL": 1.1475287145085211, "GENVOYA": 1.1475174169226596, "GLIBENCLAMIDE": 1.533929809353357, "I": 19.7594841416916, "IBUPROFEN": 1.039387540162998, "ICLUSIG": 1.1283461062379716, "IMBRUVICA": 1.3055968812462702, "INLYTA": 1.1330030413796734, "ISCOVER": 1.451697487855341, "JANUMET": 1.702447716115841, "JANUVIA": 2.0059930625830398, "JARDIANCE": 1.2261360645678772, "JORVEZA": 3.1723417888235743, "KAFTRIO": 3.1428976657812084, "KALYDECO": 1.1706378628727885, "KARVEA": 1.0866955948197785, "KISQALI": 1.1825470695614593, "KIVEXA": 1.3957304734859113, "KUVAN": 1.7973092632077905, "LEFLUNOMIDE": 1.067858049238924, "LIXIANA": 1.4388268926124164, "LONSURF": 1.5098018658582937, "LUPKYNIS": 2.3201922779563326, "LUTATHERA": 1.474672821661745, "LUTETIUM": 1.201649929457337, "LYNPARZA": 1.1727730048766063, "MELATONIN": 1.5987730805740428, "MIMPARA": 2.0797347128692896, "MISOPROSTOL": 2.303762379264908, "MOVYMIA": 2.458505551882922, "MULTAQ": 1.1796253024074503, "NEXAVAR": 1.119335529705323, "NOVONORM": 1.8176997665523125, "OCALIVA": 1.7216238960492802, "OCRELIZUMAB": 1.032499993627843, "OFEV": 2.7787216174869185, "ORKAMBI": 1.2425922666208755, "OXYBUTYNIN": 1.2971863761948308, "OZEMPIC": 1.821071339113779, "PIRFENIDONE": 1.8284858259866408, "PLAVIX": 1.22288189378203, "PRADAXA": 1.387933227259695, "RANEXA": 1.4685162283359028, "RELVAR": 1.0803314054800897, "REMSIMA": 2.6714991153295933, "RINVOQ": 1.3034937477116684, "RIXATHON": 1.1058219801242803, "ROACTEMRA": 1.0915036158961753, "RUBRACA": 1.8131812082365244, "RYBELSUS": 5.3542964623279605, "SAXENDA": 3.821252996149209, "STIVARGA": 1.0065454113268806, "SUTENT": 1.2874732937771378, "TAMIFLU": 1.3511477393954257, "TASIGNA": 1.4125702734826742, "TEDUGLUTIDE": 2.1040598194208058, "TERROSA": 1.848977014816278, "TOZINAMERAN": 1.4315886508627167, "TRIUMEQ": 1.6199810748189238, "TRULICITY": 3.685588342464788, "VALDOXAN": 1.1118359190975675, "VELMETIA": 1.8357600133883, "VELTASSA": 1.2419384587637268, "VICTOZA": 2.87260161728877, "VILDAGLIPTIN": 1.0566759897393465, "VORTIOXETINE": 1.3136617020136838, "VOTRIENT": 1.3545181138787952, "XELJANZ": 1.5835548472867973, "ZEPATIER": 1.6917228518440586, "ZYLLT": 8.253573309960352, "null": 1.1260332528894454}
\ No newline at end of file
+{"CRIZOTINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/190.json
index 68eb91b242b..e7739ece20e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/190.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9693759655373344}
\ No newline at end of file
+{"LENALIDOMIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1900.json
index 54c64bbc1ba..7ffc6819441 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1900.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1900.json
@@ -1 +1 @@
-{"null": 1.1228291695147434}
\ No newline at end of file
+{"BRAFTOVI": 31.109559251423097, "JARDIANCE": 4.09686933093602, "KEPPRA": 42.367883211935066, "OPSUMIT": 4.8888837326999655, "VIMPAT": 50.2115798337618, "null": 1.2170027619818355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1901.json
index 69a38d96186..94583fe7625 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1901.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1901.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 4.673031034860035, "BEVACIZUMAB": 10.007763600369694, "BUPRENORPHINE": 4.122501826544385, "CENOBAMATE": 449.80007570716, "CLOPIDOGREL": 2.9098652366409574, "DEXAMETHASONE": 3.113776279073339, "DULOXETINE": 5.016225245911374, "ESOMEPRAZOLE": 6.426202186288534, "FENTANYL": 3.974613394032374, "GLUCAGON": 108.83144302429626, "IBUPROFEN": 6.56315368061976, "MIDAZOLAM": 6.312785515866044, "OLANZAPINE": 8.067559918326827, "PREGABALIN": 19.386375464111808, "PROPRANOLOL": 19.668026446767044, "null": 2.909522303514924}
\ No newline at end of file
+{"CELECOXIB": 99.49787068154076, "ESOMEPRAZOLE": 369.9928078142119, "null": 1.2235297849678153}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1902.json
index 3c56595456b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1902.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1902.json
@@ -1 +1 @@
-{"ROTATEQ": 291.2914584332081}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1903.json
index 29d45d1c0c1..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1903.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1903.json
@@ -1 +1 @@
-{"FORSTEO": 36.5878024675228}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1904.json
index 2939afcd04d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1904.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1904.json
@@ -1 +1 @@
-{"ABILIFY": 2.0631288399651333, "AIMOVIG": 9.292344786464842, "BUPRENORPHINE": 3.1971127140870004, "CYMBALTA": 1.2223729149452858, "FENTANYL": 2.6818842977971213, "KEPPRA": 3.389744535924321, "LANTUS": 1.1610645722150794, "OLANZAPINE": 4.92814037139773, "ZYPREXA": 2.3856103067994647, "null": 2.6773233778093104}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1905.json
index 6260cbfece5..ec3eef3d85d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1905.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1905.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 4.805018719094041, "CLOPIDOGREL": 2.112383925938182, "ELIQUIS": 3.5677503490303475, "ENOXAPARIN": 11.12417923374929, "FENTANYL": 7.298027924456704, "GLUCAGON": 194.11095942823283, "LEVOFLOXACIN": 2.7846165817060897, "OLANZAPINE": 4.712936222785347, "PLAVIX": 2.3402767808434057, "null": 2.374626704888929}
\ No newline at end of file
+{"CLOPIDOGREL": 15.603989572946706, "COMIRNATY": 0.4122186375575088, "ELIQUIS": 26.51054603748879, "NEXAVAR": 8.327588874693083, "PEGASYS": 2.251000747453597, "PLAVIX": 9.94924435921128, "SPIKEVAX": 0.172857524576501, "VAXZEVRIA": 0.1484788809770034, "null": 0.684712786714456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1906.json
index 6f0482670e5..f371a1b1512 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1906.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1906.json
@@ -1 +1 @@
-{"null": 2.4172669215511355}
\ No newline at end of file
+{"AVANDIA": 11.845639041941055, "COMIRNATY": 1.3552409422185132, "ELIQUIS": 1.5882457210702754, "EYLEA": 9.132716233284764, "FORXIGA": 13.88023864336072, "JARDIANCE": 2.8009361313534797, "NEXAVAR": 3.117070165763841, "SPIKEVAX": 0.6291635662227499, "VAXZEVRIA": 0.6756327716151376, "null": 0.6104428133769155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1907.json
index d61f89d7735..02bb6546ca1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1907.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1907.json
@@ -1 +1 @@
-{"ROACTEMRA": 51.210197692023165, "SOLIRIS": 116.21100592287922}
\ No newline at end of file
+{"COMIRNATY": 0.6297370698202258, "null": 0.883059260509543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1908.json
index 885cd7e549a..b73ed59dad4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1908.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1908.json
@@ -1 +1 @@
-{"null": 1.3429555258382595}
\ No newline at end of file
+{"AVANDIA": 9.931168679544324, "AZILECT": 232.4543451655005, "COMIRNATY": 0.4917366951430453, "DARUNAVIR": 164.20212667360337, "SPIKEVAX": 0.5649586990357747, "VAXZEVRIA": 0.4343845331382936, "null": 0.4520019840333114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1909.json
index 8e17e958dbf..7a2368583e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1909.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1909.json
@@ -1 +1 @@
-{"ROACTEMRA": 68.89234096867287, "SOLIRIS": 40.69589737779844}
\ No newline at end of file
+{"COMIRNATY": 0.3103127250845243, "VAXZEVRIA": 0.2203977770697632, "null": 1.6945852154638152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/191.json
index db24190d91e..5517b427e86 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/191.json
@@ -1 +1 @@
-{"null": 2.140036938623944}
\ No newline at end of file
+{"COMIRNATY": 1.3364777529725624, "null": 0.1743982470966958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1910.json
index a8e987844eb..4f954b69bca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1910.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1910.json
@@ -1 +1 @@
-{"SOLIRIS": 399.2111708483052}
\ No newline at end of file
+{"COMIRNATY": 1.0414585136564367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1911.json
index ad3312cc32f..2235ef1712f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1911.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1911.json
@@ -1 +1 @@
-{"SOLIRIS": 46.76781484618534}
\ No newline at end of file
+{"null": 0.8736672188562427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1912.json
index c48579ffab0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1912.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1912.json
@@ -1 +1 @@
-{"SOLIRIS": 93.0389962069208}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1913.json
index aa613c707f7..ccb814b635d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1913.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1913.json
@@ -1 +1 @@
-{"ABILIFY": 1.5402546913769468, "ACE": 9.776473580092135, "ALL": 4.259953852420468, "ALPHA": 153.44599510511185, "ANALGESIC": 62.16154448832651, "ANGIOTENSIN": 35.925444641320624, "ANGIOTENSINCONVERTING": 94.20060036223455, "ANTIDEPRESSANT": 27.09054077122279, "ANTIDEPRESSANTS": 10.70798892837862, "ANTIHISTAMINE": 24.51375262499884, "ANTIMALARIALS": 264.4547767318826, "ANTIPLATELET": 158.5298852551079, "ANTIPSYCHOTIC": 93.52661870911469, "ARIPIPRAZOLE": 4.907639041778065, "ASENAPINE": 20.8823279788017, "ATAZANAVIR": 1.3487999860616775, "BARBITURATES": 44.89813050372836, "BENZODIAZEPINE": 61.5128329444677, "BENZODIAZEPINES": 23.4981743329371, "BETA": 108.4257044897281, "BETABLOCKER": 69.70506869533357, "BRINTELLIX": 2.8416648385783367, "BRIVARACETAM": 1.119549257463506, "BUMETANIDE": 8.070966578345233, "BUPRENORPHINE": 1.8515672008201984, "CALCIUM": 34.59229557601386, "CARDIAC": 73.08718125273737, "CARIPRAZINE": 12.966666581606033, "CELECOXIB": 3.807880799507685, "CHAMPIX": 3.953088212387927, "CLOPIDOGREL": 1.946776631954205, "CYCLIC": 246.32742747638773, "CYMBALTA": 2.1041928351977157, "DIURETICS": 12.884982657373282, "DRUG": 35.94591267230228, "DULOXETINE": 25.13490383338429, "ESOMEPRAZOLE": 3.9238201297491737, "FENTANYL": 3.276610567482437, "FYCOMPA": 1.360558486627625, "GLIBENCLAMIDE": 10.453529395671554, "GLUCAGON": 4.21177125709921, "GUANFACINE": 17.75102651727286, "HYDROCHLOROTHIAZIDE": 4.547487303790689, "IBUPROFEN": 17.97686418253335, "INSULIN": 1.046306184495416, "INTRONA": 1.9229713203534289, "INVEGA": 2.699931216496802, "IRBESARTAN": 1.09648437938078, "IRON": 4.686805178073629, "LACOSAMIDE": 1.8638313039920955, "LATUDA": 3.998016621997286, "LAXATIVES": 27.82921476166062, "LEVETIRACETAM": 2.8115928000046866, "LEVODOPA": 2.3224432487173647, "LINACLOTIDE": 87.47891839413673, "LOXAPINE": 2.830872298326427, "LURASIDONE": 25.219381301105365, "MELATONIN": 4.102613776946036, "METFORMIN": 1.7939498604291737, "MIDAZOLAM": 2.421722181057914, "MUSCLE": 25.99729175529041, "NALOXONE": 2.1268667739415084, "NATEGLINIDE": 39.61870617487866, "NOT": 14.45282963815395, "OLANZAPINE": 9.062449783459076, "OPIOID": 119.96856128627208, "OPIOIDS": 13.00993482950356, "OXYBUTYNIN": 11.62991809039005, "PALIPERIDONE": 6.398956770838945, "PANTOPRAZOLE": 5.556029366366125, "PIOGLITAZONE": 14.62938634371715, "PREGABALIN": 8.08889190626819, "PROPRANOLOL": 11.475009151590369, "RANOLAZINE": 2.134025833840385, "RASAGILINE": 11.766182062559732, "RISPERIDONE": 1.7744036986867824, "RIVAROXABAN": 13.677973024852404, "SERTRALINE": 14.871168272252872, "SILDENAFIL": 3.952708396662169, "SITAGLIPTIN": 19.66567288460777, "SKELETAL": 102.5292937671624, "SSRI": 53.30328829485575, "SUBOXONE": 1.628829986687426, "SYCREST": 1.5781867768590234, "TELMISARTAN": 1.276119214008937, "TRAZODONE": 72.86622490574653, "TRICYCLIC": 82.87532264830675, "UNKNOWN": 31.485302076391086, "UNSPECIFIED": 70.40448377862401, "VALSARTAN": 1.886478005785172, "VARENICLINE": 4.595000183765949, "VORTIOXETINE": 11.438855501790384, "XEPLION": 4.033331950118586, "ZALEPLON": 83.49165343645447, "ZIPRASIDONE": 51.41570996496304, "ZYPREXA": 2.7594506840860022, "null": 5.35933710347481}
\ No newline at end of file
+{"COMIRNATY": 3.911341788478132, "SPIKEVAX": 14.009407412121917, "TOZINAMERAN": 0.607414151130844, "VAXZEVRIA": 0.2404123820586418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1914.json
index d04b870c946..5c95bfd28dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1914.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1914.json
@@ -1 +1 @@
-{"BOSULIF": 17.375924349815794, "BUPIVACAINE": 19.028176756671066, "CYMBALTA": 2.1941027618711706, "GARDASIL": 24.36070927443529, "IMATINIB": 37.07209115343562, "LYRICA": 4.575283880701349, "OMALIZUMAB": 4.396430152421476, "QUTENZA": 64.1071452450929, "TASIGNA": 5.617520289588552}
\ No newline at end of file
+{"SOLIRIS": 1445.457490807326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1915.json
index d335d85304c..cc24e8b2562 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1915.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1915.json
@@ -1 +1 @@
-{"COMIRNATY": 1.346136282940988}
\ No newline at end of file
+{"BUPRENORPHINE": 19.010339013030578, "FENTANYL": 8.46658463202561, "LYRICA": 16.525053810660133, "null": 1.891453972287705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1916.json
index a96bbabda36..afe522115dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1916.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1916.json
@@ -1 +1 @@
-{"ADCIRCA": 19.1108755301152, "ADEMPAS": 16.339972209523477, "ARANESP": 1.8168861775077, "BUPIVACAINE": 8.58755153109131, "BYETTA": 3.262646937582889, "CINRYZE": 38.655144476502414, "CYTARABINE": 2.380440390420163, "ELIQUIS": 1.362019706614504, "ENTRESTO": 1.9108938024228053, "FENTANYL": 1.497194759293101, "FORSTEO": 2.4956854580937464, "HUMALOG": 1.4033677290448054, "JANUVIA": 2.7312366393826726, "KEPPRA": 1.3081440600772412, "NOVOSEVEN": 31.177213612479523, "OPSUMIT": 17.73794551162015, "REVATIO": 6.461475233805495, "SIMPONI": 7.707073526799235, "TRACLEER": 15.85797292867412, "null": 2.072931298625923}
\ No newline at end of file
+{"ABACAVIR": 8.032117069749779, "COMIRNATY": 0.9851373759832824, "ENBREL": 9.429902283120557, "null": 0.5527780385467791}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1917.json
index afded460f87..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1917.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1917.json
@@ -1 +1 @@
-{"GARDASIL": 25.68297293376917, "null": 2.260133068938337}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1918.json
index ec9352039c1..4abdd7ea39c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1918.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1918.json
@@ -1 +1 @@
-{"null": 3.839552982777063}
\ No newline at end of file
+{"PAZOPANIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1919.json
index 02567f6ca69..bf7cf95d918 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1919.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1919.json
@@ -1 +1 @@
-{"null": 2.5460556445726743}
\ No newline at end of file
+{"null": 1.820352752819057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/192.json
index 83618d56335..3965fda49c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/192.json
@@ -1 +1 @@
-{"null": 1.7702978896473245}
\ No newline at end of file
+{"EXJADE": 92.08825314053009, "null": 2.658657671897905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1920.json
index 97b38421354..a2ee8f263c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1920.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1920.json
@@ -1 +1 @@
-{"RUCONEST": 124.7474474094501, "SUBOXONE": 12.302430305654587, "null": 1.2577629178620418}
\ No newline at end of file
+{"null": 4.251280654869045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1921.json
index d8b09313e40..5d6f5a267ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1921.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1921.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 85.14854147169456, "ANAKINRA": 91.57334779058392, "CICLOSPORIN": 62.50440530533879, "EXJADE": 32.829084814980405}
\ No newline at end of file
+{"ABRAXANE": 12.773341168622522, "ADALIMUMAB": 0.0916301971588129, "AFINITOR": 7.6914945442322145, "AIMOVIG": 0.6182943512164023, "ALPELISIB": 18.173663496496665, "ANAKINRA": 0.3382181029142925, "ANORO": 1.312066124269739, "APIDRA": 0.3228334578953144, "ARANESP": 0.2420937498119605, "ARAVA": 0.1436028425958947, "AUBAGIO": 1.7760149643580516, "AVAMYS": 0.9975763068190834, "AVASTIN": 0.5706177039082558, "AVONEX": 2.9666836350559715, "BENLYSTA": 0.884556263333305, "BETAFERON": 2.9509869245289586, "BEVACIZUMAB": 0.5476611857040251, "BONVIVA": 0.9394061948401232, "BUPRENORPHINE": 0.2572723447255932, "BYDUREON": 0.3200948960587831, "BYETTA": 1.1648493769828956, "CAELYX": 1.979701308528912, "CAPECITABINE": 6.388895182797506, "CARMUSTINE": 1.4921069543515024, "CELLCEPT": 0.7939145098579931, "CHAMPIX": 0.0917436429289299, "CICLOSPORIN": 0.1904470347741816, "CIMZIA": 1.2206847042157432, "COAPROVEL": 0.5086098455832501, "COMIRNATY": 0.055592198383743, "COSENTYX": 1.428010298555349, "CYMBALTA": 0.319347917259811, "DENOSUMAB": 5.430666060399886, "DEXAMETHASONE": 0.1076111310010238, "DOCETAXEL": 2.2611314101877427, "DOXORUBICIN": 0.7136874245489265, "ELIQUIS": 0.7765729047111144, "ENBREL": 0.5369363298593264, "ENTYVIO": 0.7680970468222795, "ERIBULIN": 7.494784919849463, "ESMYA": 2.2236743958010665, "EVENITY": 1.513716623047395, "EVEROLIMUS": 3.393652508877239, "EVISTA": 13.390285082471236, "EXFORGE": 0.6582761021402769, "FAMPYRA": 0.8138324779134692, "FASENRA": 1.0006749533406816, "FASLODEX": 4.947904493670108, "FORSTEO": 1.9053631546015424, "FULVESTRANT": 12.552386066509836, "GARDASIL": 0.075311833449226, "HERCEPTIN": 1.8988854533118256, "HIZENTRA": 0.7787997828829474, "HUMALOG": 1.3906872852924703, "HUMIRA": 0.3867288644027665, "IBRANCE": 0.7531064146576708, "INSULIN": 0.9180583374226468, "JAKAVI": 0.1867016123312985, "JANUMET": 0.6502900364735479, "JANUVIA": 0.5644915944745381, "JARDIANCE": 0.6374213426616918, "KEPPRA": 0.2703285036694144, "KESIMPTA": 2.3297094260879407, "KEYTRUDA": 0.1149072148916621, "KISQALI": 12.82799912393435, "LANTUS": 1.7356812858013204, "LEMTRADA": 0.6662756992997437, "LEVEMIR": 1.467505743557885, "LYNPARZA": 1.144041986219103, "LYRICA": 0.311777338691678, "MAVENCLAD": 2.160357599162469, "MEPOLIZUMAB": 0.1625670988520974, "METHOTREXATE": 0.8675138698967997, "MICARDIS": 0.7544149612205188, "NEULASTA": 1.4331176095550415, "NOVORAPID": 0.2713899619728606, "NPLATE": 0.6059924254970362, "NUCALA": 0.3523045213395718, "OMALIZUMAB": 1.9293204451929893, "ONGLYZA": 1.231812897140457, "OPSUMIT": 0.3097003497942892, "PACLITAXEL": 3.0103247338890853, "PEGASYS": 0.3162799760828074, "PEGINTRON": 0.1600019611540018, "PIQRAY": 5.626746484333479, "PLAVIX": 0.0754223956006543, "PLEGRIDY": 0.7506277025216792, "RIBOCICLIB": 11.848224408275744, "RINVOQ": 1.0989448477621342, "RITUXIMAB": 0.1917650894011808, "ROACTEMRA": 2.3550505574498497, "SAXENDA": 1.910917562543603, "SHINGRIX": 0.3229612235695093, "SIMPONI": 2.4639818754248943, "SKYRIZI": 2.2343051311679014, "SOLIRIS": 0.3625530693397614, "SPIKEVAX": 0.0335895106167328, "SPRYCEL": 0.2471323215230779, "STELARA": 3.56999425568326, "SUBOXONE": 0.355625751346806, "SUTENT": 0.1310921800148679, "TASIGNA": 0.4355624614933963, "TAXOTERE": 2.3841679570405825, "TESTOSTERONE": 3.892036576317762, "TOVIAZ": 0.6647925746330237, "TOZINAMERAN": 0.1123124768185911, "TRACLEER": 0.3626345280831814, "TRELEGY": 1.8001669389823778, "TREMFYA": 3.50585648379731, "TRULICITY": 0.991569971943178, "VAXZEVRIA": 0.0283241671222773, "VICTOZA": 1.5415528721216931, "XELJANZ": 1.219861206788952, "XELODA": 0.7775370033509262, "XOLAIR": 3.7785167452857, "ZOSTAVAX": 0.8224769990133777, "ZYPREXA": 0.3549829768935383, "null": 5.385342346676985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1922.json
index 9374e9141f3..b9b294a3073 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1922.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1922.json
@@ -1 +1 @@
-{"VFEND": 48.99452248144711}
\ No newline at end of file
+{"AFINITOR": 4.039245095720937, "AUBAGIO": 3.647510563835208, "BYDUREON": 4.057599424263143, "COMIRNATY": 0.1192158913763241, "DOCETAXEL": 3.4050415744625635, "ENBREL": 1.4570684498439157, "ENTYVIO": 2.071656875214885, "FASENRA": 7.1081594541652295, "FASLODEX": 16.863543192432665, "FORXIGA": 2.4454035074935554, "IBRANCE": 1.0682141517962462, "JARDIANCE": 1.3351455140810873, "LANTUS": 1.3337057213860504, "PLEGRIDY": 8.168909721700714, "RINVOQ": 11.434171600555716, "SKYRIZI": 20.27669792555257, "SPIKEVAX": 0.0882274511862678, "TOZINAMERAN": 0.167801921712987, "XELJANZ": 7.835227555491443, "ZOSTAVAX": 1.029789678212779, "null": 3.609680117643787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1923.json
index 5409740afc9..24b61d37a5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1923.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1923.json
@@ -1 +1 @@
-{"ARANESP": 22.16684485682795, "BASILIXIMAB": 385.94920878239367, "CELLCEPT": 27.68925373464343, "CICLOSPORIN": 68.93851548735573, "MYCOPHENOLATE": 96.10346077841476, "SOLIRIS": 8.122790420817836, "TACROLIMUS": 74.50705244939448}
\ No newline at end of file
+{"null": 2.5183447291105288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1924.json
index 6fcc97bcaff..1aa5ed6a2a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1924.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1924.json
@@ -1 +1 @@
-{"CICLOSPORIN": 118.51793630474916}
\ No newline at end of file
+{"null": 5.789571689999923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1925.json
index 5c4f30a9ad8..d4753cbda4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1925.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1925.json
@@ -1 +1 @@
-{"ATRIPLA": 4.588244855906956, "BONVIVA": 22.27329326575435, "ELIQUIS": 1.34307991216399, "EVENITY": 111.38521889177213, "EVISTA": 76.89606127282046, "IBRANCE": 1.01358197242457, "STRIBILD": 5.807050585340042, "TEDUGLUTIDE": 119.8384336569958, "TRUVADA": 5.565300872796311, "XELJANZ": 1.5876284350378056, "XTANDI": 4.798983212938757, "ZOMETA": 42.66425174097731, "null": 1.3746113374720987}
\ No newline at end of file
+{"ABEMACICLIB": 93.15999432842683, "ABRAXANE": 138.3994817997619, "AFINITOR": 30.025304783360625, "ALPELISIB": 78.26872288510475, "AVASTIN": 2.022059222445583, "BEVACIZUMAB": 2.270013559700933, "CAELYX": 13.844215625537611, "CAPECITABINE": 33.45557226436214, "COMIRNATY": 0.0197907954632293, "COSENTYX": 0.445968327082366, "DENOSUMAB": 17.192373717274624, "DOCETAXEL": 14.596554217244952, "DOXORUBICIN": 1.8599273450109064, "ELIQUIS": 0.5077114044553881, "ERIBULIN": 56.213053812705134, "EVEROLIMUS": 39.16397170009321, "EVISTA": 3.1334704603262225, "FASLODEX": 27.57988946072983, "FORSTEO": 0.5113238498127511, "FULVESTRANT": 111.61207427770832, "HERCEPTIN": 10.083868526044066, "IBRANCE": 6.34139955419433, "KEPPRA": 0.4891356106203406, "KISQALI": 49.261672259770044, "NEULASTA": 1.71977207197164, "PACLITAXEL": 4.32039000032839, "PIQRAY": 43.98467014680431, "RIBOCICLIB": 106.076078243657, "STELARA": 0.6405553310877613, "TESTOSTERONE": 8.902801016524183, "TRODELVY": 4.112835023218993, "null": 2.0182195736388278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1926.json
index ff86ce33a61..35daec0f501 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1926.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1926.json
@@ -1 +1 @@
-{"null": 2.883764207588273}
\ No newline at end of file
+{"AFINITOR": 45.77802293862209, "CAPECITABINE": 27.31789418372708, "COMIRNATY": 0.103002815549613, "DENOSUMAB": 32.63378619914449, "DOCETAXEL": 22.72097530100633, "EVISTA": 18.44683462053573, "FASLODEX": 94.13303397037812, "FORSTEO": 1.8634678795047557, "FULVESTRANT": 53.29411403803815, "HERCEPTIN": 30.195068805959075, "IBRANCE": 3.823253353087021, "KISQALI": 21.115083688579197, "LANTUS": 0.8847109715392639, "NEULASTA": 8.554132483182011, "PACLITAXEL": 20.96213965481388, "RIBOCICLIB": 24.06288820845183, "null": 0.6521436535562548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1927.json
index 744d799ea36..73584b1714f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1927.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1927.json
@@ -1 +1 @@
-{"null": 2.848173647013041}
\ No newline at end of file
+{"ABATACEPT": 22.904182607066375, "null": 1.6062827101697863}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1928.json
index 82ba7d17029..448da5d80ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1928.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1928.json
@@ -1 +1 @@
-{"ABILIFY": 66.12822527511668, "SIFROL": 242.80041011613463, "null": 1.3068555317445192}
\ No newline at end of file
+{"ABACAVIR": 9.520238510807271, "ABATACEPT": 39.70986709121448, "ADALIMUMAB": 125.3588928616272, "AFINITOR": 2.5558338840323898, "ARAVA": 2.0314576374037085, "BOTULINUM": 17.60669104865008, "ENTYVIO": 3.234599580039717, "null": 0.1277029637358194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1929.json
index a09e187994e..66e8e8260d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1929.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1929.json
@@ -1 +1 @@
-{"ABILIFY": 56.928017852095344, "AZILECT": 134.35493495481504, "COMTAN": 86.35070521208279, "ENTACAPONE": 140.37564444815737, "LEVODOPA": 252.64324083253203, "SIFROL": 722.4348656547571, "null": 1.2152897484294551}
\ No newline at end of file
+{"ABATACEPT": 88.52794108854617, "ADALIMUMAB": 98.71375960253198, "AIMOVIG": 7.79164675246818, "AMINOSALICYLIC": 27.97891107944217, "APREMILAST": 18.235486175493147, "ARAVA": 3.725098604859497, "BOTULINUM": 7.241589764158109, "CERTOLIZUMAB": 43.569845236308325, "RITUXIMAB": 1.9771295566322664, "null": 0.0312664651083457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/193.json
index aaa0871e196..604ed62ceff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/193.json
@@ -1 +1 @@
-{"COMIRNATY": 4.903241374154537, "HIZENTRA": 8.922399275127102, "MMRVAXPRO": 3.4670877470531285, "ROACTEMRA": 4.555353574159624, "SPIKEVAX": 2.0970263571297507, "VAXZEVRIA": 5.1306671196848495}
\ No newline at end of file
+{"CYTARABINE": 22.86089195551355, "SUTENT": 7.1105715673798695, "null": 0.6872665387038563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1930.json
index d64dc0fafe2..4747eee7c7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1930.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1930.json
@@ -1 +1 @@
-{"SPIKEVAX": 24.183180943652648}
\ No newline at end of file
+{"AFINITOR": 20.87735875708968, "FASLODEX": 72.79669239188901, "IBRANCE": 24.073838371410297, "null": 0.3865658293924836}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1931.json
index b522bf5a45b..d64e083928c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1931.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1931.json
@@ -1 +1 @@
-{"SPIKEVAX": 8.962391645816457}
\ No newline at end of file
+{"FARESTON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1932.json
index c2be138c36a..810ba4fdfba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1932.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1932.json
@@ -1 +1 @@
-{"BUDESONIDE": 2.1092936503162014, "CICLOSPORIN": 5.873925952650038, "CUBICIN": 20.141778659943853, "CYTARABINE": 8.585450407730658, "KEYTRUDA": 1.7013113614947657, "XOLAIR": 5.262822873659927, "null": 1.5552373803206585}
\ No newline at end of file
+{"null": 0.5500856115978128}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1933.json
index 55a73c3207c..8ad4bbcbd4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1933.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1933.json
@@ -1 +1 @@
-{"COVID19": 6.657436399885064, "SPIKEVAX": 5.451270457966126}
\ No newline at end of file
+{"ACLIDINIUM": 133.00163975369662, "ANORO": 25.04691404904983, "BYETTA": 10.777439124763731, "IBRANCE": 5.3557649830472815, "KEYTRUDA": 2.5209981571738136, "XOLAIR": 6.142662017505936, "null": 3.1431983970904267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1934.json
index ff1b5944208..667e90a7bd6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1934.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1934.json
@@ -1 +1 @@
-{"SPIKEVAX": 8.634602311091168}
\ No newline at end of file
+{"COMIRNATY": 1.605614558235714, "SPIKEVAX": 0.7785188220175254, "TOZINAMERAN": 0.7968847207366452, "VAXZEVRIA": 0.2009681295003447, "null": 1.4340245437169}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1935.json
index 2c2e42c2e1f..b5212fe4fb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1935.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1935.json
@@ -1 +1 @@
-{"SPIKEVAX": 28.57885678946372}
\ No newline at end of file
+{"COMIRNATY": 1.1590291829054329, "FULVESTRANT": 21.597353330191915, "GARDASIL": 4.038560196684616, "PEGASYS": 1.966502389419294, "SPIKEVAX": 0.3086755583037379, "VAXZEVRIA": 0.1746851955507409, "null": 1.6139661796609257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1936.json
index a6df7d7ebc9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1936.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1936.json
@@ -1 +1 @@
-{"ENTRESTO": 83.59527123745303, "null": 1.039897555002841}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1937.json
index 871a8872b95..49a57438045 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1937.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1937.json
@@ -1 +1 @@
-{"GARDASIL": 47.5232163302004, "SPIKEVAX": 7.83115241830028}
\ No newline at end of file
+{"null": 2.015987029138001}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1938.json
index f5d9ee0d437..59bce364fd3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1938.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1938.json
@@ -1 +1 @@
-{"APREPITANT": 490.7821148960112, "SPIKEVAX": 6.532777321720162}
\ No newline at end of file
+{"COMIRNATY": 3.1022428704898077, "ELLAONE": 58.53795787571606, "ESMYA": 22.96720578288431, "SPIKEVAX": 1.4312948919953157, "TOZINAMERAN": 0.7104861039858695, "VAXZEVRIA": 0.2261495871338479, "null": 1.3548178920433755}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1939.json
index 400bc3ceefc..4044adeaca7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1939.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1939.json
@@ -1 +1 @@
-{"APREPITANT": 127.24802931445866, "DEXAMETHASONE": 19.381929803373566, "SPIKEVAX": 6.123801611806822}
\ No newline at end of file
+{"CAPECITABINE": 15.680827329561756, "COMIRNATY": 0.5110569416427839, "ELIQUIS": 2.583963665184234, "FORSTEO": 4.144944076315723, "IBRANCE": 2.439650192806177, "MEPOLIZUMAB": 22.810568330639487, "SPIKEVAX": 0.2885467910125185, "null": 1.3495784922366956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/194.json
index 44e660846ce..601dc94c193 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/194.json
@@ -1 +1 @@
-{"KEYTRUDA": 2.96330430968245, "null": 10.12488604992442}
\ No newline at end of file
+{"ABIRATERONE": 98.12491820156411, "ADENURIC": 13.70516906522115, "ALIMTA": 2.617058852760312, "ARANESP": 0.905703573079872, "AVANDAMET": 60.71043296661498, "AVANDIA": 38.27116578786335, "AVASTIN": 1.3686412292234509, "BRILIQUE": 14.18123879751911, "CAPECITABINE": 3.011579552348646, "CHAMPIX": 1.7080665062020222, "CICLOSPORIN": 0.383241701312747, "CLOPIDOGREL": 4.993751042084176, "COMIRNATY": 0.657106597210982, "DEXAMETHASONE": 1.1818390127239349, "ELIQUIS": 0.8321934424345837, "ENTRESTO": 0.6634719568035751, "FORSTEO": 0.7617482517371312, "ICLUSIG": 7.110595663817508, "INLYTA": 2.188402574626931, "JAKAVI": 2.2112747198431477, "JANUVIA": 0.7785749711269669, "JARDIANCE": 0.560388781558128, "KEYTRUDA": 0.783284046194579, "KYPROLIS": 8.319614759999924, "MICARDIS": 1.685920697209827, "MODERNA": 0.8948213496654277, "NEXAVAR": 3.2599777359171687, "NILOTINIB": 19.27922283498472, "NPLATE": 3.087925402979168, "NUCALA": 1.91422851132058, "OFEV": 4.000394916872363, "OLANZAPINE": 1.7106929438163825, "PLAVIX": 3.987191417086167, "RITUXIMAB": 1.1546182684571862, "ROACTEMRA": 1.7290346843070803, "SIMPONI": 0.657232554369379, "SPIKEVAX": 0.3129838225452745, "STELARA": 1.3636842118388848, "STIVARGA": 1.0248813842411288, "SUTENT": 0.5061640558201503, "TASIGNA": 5.481912205131358, "TICAGRELOR": 4.833472647267703, "TOZINAMERAN": 0.1527849132007225, "VAXZEVRIA": 0.4775993960515418, "VIAGRA": 1.8409092516002703, "VOTRIENT": 0.8084028023522071, "XOLAIR": 0.6717257394909695, "null": 0.8086881279333333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1940.json
index 8db8add3957..85fd8edd838 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1940.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1940.json
@@ -1 +1 @@
-{"SPIKEVAX": 28.635263974628977}
\ No newline at end of file
+{"COMIRNATY": 0.851317075553061, "null": 0.959972683819471}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1941.json
index c70bab1bd56..d379008a45f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1941.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1941.json
@@ -1 +1 @@
-{"ADCIRCA": 10.458245977333153, "ADEMPAS": 10.726858528952008, "AFINITOR": 7.396489726408137, "CICLOSPORIN": 2.173669508551286, "COMIRNATY": 1.952777034882188, "COSENTYX": 8.250146883396864, "DOCETAXEL": 1.9559844892535985, "DOXORUBICIN": 3.822329859486565, "ENTRESTO": 4.149549186116058, "EXFORGE": 4.455714339930749, "EXJADE": 2.2500085031681465, "JAKAVI": 18.30817143073069, "MEKINIST": 3.572676712201394, "METFORMIN": 26.42028381085322, "OMALIZUMAB": 4.1753263394866265, "OPSUMIT": 16.37921211863474, "PASIREOTIDE": 143.31916048400728, "RUXOLITINIB": 10.24179554525715, "TAMIFLU": 1.972932383035177, "TASIGNA": 9.48085887258679, "TRACLEER": 11.830409118923937, "VOTRIENT": 1.006366801348131, "XOLAIR": 3.315331822590602}
\ No newline at end of file
+{"null": 1.920349924069633}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1942.json
index 6c5fd5988ed..65b0fa474f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1942.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1942.json
@@ -1 +1 @@
-{"AFINITOR": 9.22591754807395, "ALISKIREN": 66.99145028005182, "CICLOSPORIN": 7.485942720321299, "COSENTYX": 2.954334194473744, "EXJADE": 12.400106385308838, "JAKAVI": 4.968820546045316, "MEKINIST": 4.156892797559645, "METFORMIN": 22.234402459292085, "NOVOSEVEN": 1018.7300870919788, "OPSUMIT": 8.339735487176707, "TASIGNA": 13.895689962762471, "TRACLEER": 7.660170385690843}
\ No newline at end of file
+{"null": 1.7424497548446465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1943.json
index 1f2b48cc834..147b10ddc03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1943.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1943.json
@@ -1 +1 @@
-{"COMIRNATY": 3.2939374752118877}
\ No newline at end of file
+{"COMIRNATY": 6.080586087402606, "SPIKEVAX": 2.017499926551316, "VAXZEVRIA": 0.2554295763300523, "null": 0.4098530324681504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1944.json
index d1cda516fb2..f57903994a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1944.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1944.json
@@ -1 +1 @@
-{"ABILIFY": 3.610408947119077, "AIMOVIG": 22.57161702308696, "AUBAGIO": 1.6413181996378234, "AZATHIOPRINE": 3.740409511989313, "CYMBALTA": 3.004044136404002, "ESOMEPRAZOLE": 14.395775859399857, "FENTANYL": 1.308443297388098, "FIRDAPSE": 8.9172810656474, "GARDASIL": 7.596917342288229, "HUMALOG": 2.6416962926804564, "IBRANCE": 1.0846459972295497, "IRBESARTAN": 5.549178584198931, "KEPPRA": 3.8571530697039513, "LANTUS": 3.592998592731743, "LYRICA": 4.258872841361994, "SUBOXONE": 3.867238544252468, "VIAGRA": 3.0928681978910766, "XELJANZ": 2.365106357378839, "null": 1.1769106942371033}
\ No newline at end of file
+{"CHAMPIX": 1.6293011228083516, "COMIRNATY": 3.284806941832502, "CYMBALTA": 1.0581060165699494, "EPIVIR": 10.050274068551545, "FORSTEO": 1.8983292713020343, "INVEGA": 50.34546184779829, "KAFTRIO": 6.03492197202286, "MODERNA": 1.6359679530777484, "OLANZAPINE": 1.6355564234974092, "SPIKEVAX": 0.8846904451788488, "TOZINAMERAN": 0.4378725647435282, "VAXZEVRIA": 0.1374691731587982, "ZYPREXA": 3.420498989317903, "null": 1.3420675375610425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1945.json
index d20ffbb355b..94fcf727428 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1945.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1945.json
@@ -1 +1 @@
-{"ABATACEPT": 2.791753330346998, "ABILIFY": 1.6248997380058572, "ACLASTA": 1.4050861579832, "ACLIDINIUM": 4.230613060217498, "ACTRAPID": 7.612795996865404, "ADALIMUMAB": 4.790480850229275, "ADCIRCA": 1.2237590739891362, "ADEMPAS": 1.8026238757866613, "AERIUS": 1.0971734304148115, "AGOMELATINE": 3.023400683919979, "ALPELISIB": 1.1348279429350296, "AMBRISENTAN": 1.62378781009876, "AMIKACIN": 3.7208174939073615, "AMINOSALICYLIC": 1.1456128804287329, "ANAKINRA": 2.6571572716387206, "ANIDULAFUNGIN": 7.618217268206459, "ANORO": 7.020843906629771, "APIXABAN": 1.2460881611218533, "APREMILAST": 2.8278864145491256, "APREPITANT": 6.533140997070747, "APTIVUS": 1.3595286660329675, "ARANESP": 3.9780745604780954, "ARAVA": 3.77624779827956, "ARIPIPRAZOLE": 1.8957771362922864, "ARTESUNATE": 7.384056038991352, "AUBAGIO": 3.0025560565901914, "AVAMYS": 2.5644233008085164, "AZATHIOPRINE": 2.8368053394147976, "AZILECT": 1.3784034430703036, "AZTREONAM": 1.565671652090785, "BELIMUMAB": 1.320918626157143, "BENLYSTA": 2.407857266631723, "BENRALIZUMAB": 4.475589521039869, "BETMIGA": 1.509231111311644, "BOSENTAN": 4.218473327183254, "BOSULIF": 1.041023149274129, "BRINTELLIX": 1.6931741602980708, "BUDESONIDE": 1.2391303789211068, "BUPIVACAINE": 1.028099681445478, "CABOTEGRAVIR": 1.579150752405806, "CANAKINUMAB": 6.664073304317863, "CANNABIDIOL": 2.429682633592164, "CARBIDOPA": 2.538841966981786, "CASPOFUNGIN": 2.372097256304457, "CELECOXIB": 1.5588805215972628, "CELSENTRI": 2.139694542240019, "CETRORELIX": 11.616088748189116, "CICLOSPORIN": 1.325325507764913, "CIMZIA": 1.4881394148502394, "CINACALCET": 1.1964883476726444, "CINRYZE": 1.0412828072334357, "CIRCADIN": 1.0751365282588778, "CLOPIDOGREL": 1.027023235946966, "COMTESS": 3.436668261909721, "COSENTYX": 1.5692977963475117, "CRESEMBA": 2.567041428096967, "CUBICIN": 1.5040048098928498, "DACLIZUMAB": 13.027889767419628, "DAPAGLIFLOZIN": 1.6702372809568091, "DAPTOMYCIN": 1.6311237410687462, "DARBEPOETIN": 4.316333227440547, "DEFITELIO": 2.65076977535152, "DEXAMETHASONE": 1.845154205704153, "DEXMEDETOMIDINE": 1.416085460679724, "DIFICLIR": 2.6499595569985366, "DOLUTEGRAVIR": 2.037388976246975, "DULOXETINE": 1.3151438599153205, "DUORESP": 4.789880979388072, "DUPILUMAB": 1.6301486559611054, "DUPIXENT": 1.770521693912335, "EBIXA": 1.624563696541164, "EDURANT": 1.1327600574124763, "EFAVIRENZ": 1.7846064205329606, "EMEND": 1.651572383398079, "ENBREL": 3.388936142415284, "ENOXAPARIN": 1.4232167587167022, "ENTYVIO": 2.03123802190726, "ENZALUTAMIDE": 1.1389747153778502, "EPIDYOLEX": 3.055847864664908, "EPIVIR": 1.002867127008671, "ERELZI": 1.650803524509639, "ERTAPENEM": 2.5640313461279045, "ESMYA": 2.6316441507530794, "ESOMEPRAZOLE": 1.3508651513963412, "ETANERCEPT": 2.862439595385037, "EVEROLIMUS": 1.3254282206514592, "FAMPRIDINE": 2.717601902745883, "FASENRA": 1.8411776559759832, "FEBUXOSTAT": 1.1005098845676695, "FENTANYL": 1.0782890522421198, "FESOTERODINE": 1.9756116282719312, "FIRDAPSE": 2.3767478608863386, "FLUTICASONE": 4.573638202142165, "FYCOMPA": 1.2770681055900412, "GALAFOLD": 1.0090539178408504, "GANCICLOVIR": 2.089118306521664, "GLUCAGON": 1.950860833101229, "GOLIMUMAB": 1.4358345337573102, "GRANISETRON": 5.928385868020947, "HUMAN": 1.3817342648537807, "HUMIRA": 1.549287926879991, "HYDROCORTISONE": 2.3490571979750725, "IBUPROFEN": 1.0176817969535872, "IDACIO": 3.106084975112421, "IKERVIS": 2.027760630417852, "ILOPROST": 5.788753732604919, "IMIQUIMOD": 1.514124483467079, "INCRUSE": 2.3389170161476804, "INFLECTRA": 7.720722115430031, "INFLIXIMAB": 4.073503342736783, "INTEGRILIN": 1.892429031710348, "KESIMPTA": 1.186648336114642, "KINERET": 4.394074219096827, "LACOSAMIDE": 3.0838644583301016, "LAMIVUDINE": 1.5664618025322754, "LEFLUNOMIDE": 2.159577601642348, "LEMTRADA": 1.7819870282588337, "LEVETIRACETAM": 2.5681435723474646, "LEVODOPA": 2.567978954563276, "LEVOFLOXACIN": 1.0797313792199066, "LOPINAVIR": 2.139572638776511, "LOXAPINE": 3.7307338277763296, "LURASIDONE": 3.2758868914843324, "LUTATHERA": 1.2422838148135134, "LYRICA": 1.2459921644193503, "MACITENTAN": 2.2083024410575582, "MELATONIN": 2.0189659080269644, "MEMANTINE": 1.080192244158878, "MEPOLIZUMAB": 1.3028559552650856, "MERCAPTOPURINE": 1.1224067185768858, "METHOTREXATE": 2.670489593238829, "MICAFUNGIN": 1.2922270221203782, "MIRVASO": 10.170270220550512, "MOVYMIA": 2.057962821253692, "MULTAQ": 2.122456518787383, "MYCOPHENOLATE": 2.071515572707461, "NOT": 1.208022612427425, "NOVOSEVEN": 1.4034205363918448, "NUCALA": 2.546617939314827, "OLANZAPINE": 1.6387637648605922, "OLYSIO": 1.1219270238238264, "OPSUMIT": 3.733253601802327, "OSELTAMIVIR": 2.681991856107963, "OZEMPIC": 1.039438405665143, "PANTOPRAZOLE": 1.3672149040671746, "POSACONAZOLE": 2.6823732668275038, "POTELIGEO": 1.0849427804937548, "PRAMIPEXOLE": 2.5570218399762155, "PROPRANOLOL": 1.6538882824576997, "QUTENZA": 2.0469474345988337, "RAPAMUNE": 1.776339593161514, "REAGILA": 1.778888627988522, "REGORAFENIB": 1.7288902038734868, "RELVAR": 2.513717048238201, "REMSIMA": 3.03605788152068, "REVATIO": 3.4193092633835183, "RILUTEK": 2.529703687805848, "RILUZOLE": 2.104734489129125, "RIOCIGUAT": 9.511550497386043, "RISPERIDONE": 1.7585552500284911, "RITUXIMAB": 1.0414424679792753, "RIVAROXABAN": 1.113385321872498, "RUCONEST": 4.563913703395952, "RYBELSUS": 1.179080405258383, "RYEQO": 5.51454914662635, "SAMSCA": 1.381762219950961, "SIFROL": 2.0629572914169625, "SILDENAFIL": 1.9814332570308368, "SIMPONI": 1.0110299343487203, "SIRTURO": 1.410190388410861, "SITAGLIPTIN": 1.6047555158506523, "SOLIRIS": 3.835520609419027, "SOMATROPIN": 2.159508749101408, "SPIRONOLACTONE": 1.0765886140504195, "STALEVO": 1.041864991356566, "STELARA": 1.4185081849775212, "SUBOXONE": 1.5210678266743225, "TACROLIMUS": 1.0897056890547028, "TERIFLUNOMIDE": 1.2745089059363808, "TERROSA": 1.6479861763589354, "TIGECYCLINE": 4.308569571404217, "TIVICAY": 1.0342384058243848, "TOBI": 2.514484175069501, "TOBRAMYCIN": 2.067618466170088, "TOCILIZUMAB": 1.873867997481981, "TOFACITINIB": 3.109116022126352, "TORISEL": 1.663780955367134, "TOUJEO": 1.0704439115603643, "TOVIAZ": 1.7364416400168978, "TOZINAMERAN": 1.0482279504565095, "TRACLEER": 4.040791798761954, "TRELEGY": 3.3019897589658624, "TREMFYA": 1.6532504734978373, "TRIUMEQ": 1.6593389235288905, "UMECLIDINIUM": 1.140057419198674, "UPTRAVI": 2.807826176019775, "UROREC": 1.7615722312366937, "VARENICLINE": 3.427877759909617, "VEDOLIZUMAB": 3.1888535048955946, "VEKLURY": 1.2573177604358745, "VERKAZIA": 40.60543900168347, "VFEND": 1.900691088111771, "VIGABATRIN": 2.5670856482066577, "VORICONAZOLE": 2.8745137952545097, "VORTIOXETINE": 4.214090537624172, "XELJANZ": 9.220630237333856, "ZAVESCA": 4.862491191696674, "ZEJULA": 1.200492219353529, "ZYCLARA": 1.0250305510590965, "null": 1.036948585459206}
\ No newline at end of file
+{"COMIRNATY": 1.2589287449158495, "KEPPRA": 4.43085251984712, "SPIKEVAX": 0.2934787084639601, "VAXZEVRIA": 0.3041446092875418, "null": 2.50793622371742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1946.json
index 4a8cd6f67db..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1946.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1946.json
@@ -1 +1 @@
-{"ATAZANAVIR": 21.73677903698688, "BUDESONIDE": 2.7118645190785005, "IRBESARTAN": 19.92712319398857, "XYREM": 21.35360636598173, "null": 3.3687532136732954}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1947.json
index 2bfb0f40d0a..73f5a4edfc0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1947.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1947.json
@@ -1 +1 @@
-{"EFAVIRENZ": 86.96421101221651, "NAGLAZYME": 102.7254168767744, "null": 1.4915111648939994}
\ No newline at end of file
+{"null": 2.0780883378436545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1948.json
index 9dc62f0ad30..711fee979bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1948.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1948.json
@@ -1 +1 @@
-{"null": 1.5056734221207937}
\ No newline at end of file
+{"COMIRNATY": 0.9488950723463112, "ELIQUIS": 7.620085179341462, "null": 1.5518177283319678}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1949.json
index 64894401e5a..c2dd015fca3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1949.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1949.json
@@ -1 +1 @@
-{"EFAVIRENZ": 421.4681794148452}
\ No newline at end of file
+{"COMIRNATY": 0.7618518042552344, "ELIQUIS": 8.577957910419274, "IBRANCE": 16.944207912524966, "null": 0.6895619877308906}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/195.json
index 9741f0a9419..0618a691eb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/195.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2888067346059555}
\ No newline at end of file
+{"null": 0.8939870514157086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1950.json
index 82c80a115d5..e74f6153f5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1950.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1950.json
@@ -1 +1 @@
-{"ABATACEPT": 4.399914261458783, "ABILIFY": 1.4449969672242249, "ACETAMINOPHEN": 6.406938621179766, "ADALIMUMAB": 4.103876241969562, "ADVAGRAF": 2.001633942195321, "AERIUS": 1.9350084512736023, "ALISKIREN": 8.285165651601863, "ALL": 1.299410574844938, "AMINOSALICYLIC": 1.01920184087581, "APIDRA": 1.5095967745398051, "APREMILAST": 2.6737909583585724, "APREPITANT": 8.304303866771997, "APROVEL": 1.7130343142837183, "ARAVA": 1.5178668681985648, "AXITINIB": 1.402623940681568, "AXURA": 3.519031613972401, "AZILECT": 4.985940526503135, "BETMIGA": 1.1871087928782438, "BORTEZOMIB": 1.3235263168285518, "BRIMONIDINE": 2.592223063147274, "BRINTELLIX": 1.6074436035075124, "BUPRENORPHINE": 1.6926792224382368, "CANNABIDIOL": 2.5346209226252983, "CARBIDOPA": 2.06567090394323, "CARFILZOMIB": 1.47547399609998, "CHAMPIX": 1.5501747059255615, "CHLORHEXIDINE": 7.016580965850869, "CIMZIA": 2.7868644743756663, "CIRCADIN": 2.739433826776972, "COAPROVEL": 3.013941512843148, "COLESEVELAM": 36.001778756256506, "COMTAN": 4.003169135381908, "COMTESS": 3.301902537618365, "CRESEMBA": 1.110390646467633, "CYMBALTA": 4.839952156795763, "DAKLINZA": 1.9023792799464412, "DELTYBA": 3.070327544150323, "DESLORATADINE": 1.0628195583588986, "DEXAMETHASONE": 1.247772567088809, "DRONEDARONE": 4.661893887688536, "DULOXETINE": 1.895643751015924, "EBIXA": 11.074438934625292, "EMTRICITABINE": 1.3142540468653765, "ENTACAPONE": 1.691999544597996, "ENZALUTAMIDE": 1.9421718520363656, "ERTAPENEM": 3.6128796141465065, "ESOMEPRAZOLE": 1.190201528743433, "EXELON": 3.632108723154914, "FABRAZYME": 4.7280342313327886, "FOTIVDA": 1.9324576548811816, "FYCOMPA": 2.0225248441151784, "GILENYA": 1.168290253547243, "GLIBENCLAMIDE": 2.835950971867355, "HARVONI": 1.00408096586073, "HUMALOG": 1.1196902282720076, "HYDROCHLOROTHIAZIDE": 1.5405382139342654, "IMNOVID": 1.397021355212998, "INVANZ": 8.610774818277607, "IRBESARTAN": 1.8702041131800289, "KEPPRA": 2.1903142775443274, "KYMRIAH": 1.5229955042142789, "LANTUS": 1.1164448734885153, "LATUDA": 1.06339654486778, "LEVETIRACETAM": 1.7194184824381649, "LEVODOPA": 1.7156130650518815, "LYRICA": 3.559795804869992, "LYSODREN": 1.9266034522412887, "MABCAMPATH": 1.3022768654049868, "MELATONIN": 2.133226659321523, "MEMANTINE": 4.257124430776476, "MICARDIS": 1.0430609100745574, "MICARDISPLUS": 1.3516888225953243, "MIDAZOLAM": 1.5430061664122483, "MIRABEGRON": 1.788717534581648, "NALOXONE": 4.6346838281898, "NEUPRO": 2.4794313637043484, "NOVONORM": 3.2488741302965143, "NOXAFIL": 1.033171174799934, "OCRELIZUMAB": 1.6562905187966264, "OLANZAPINE": 2.47957690537733, "OLYSIO": 1.1989208345920666, "OPTIMARK": 5.433235245456891, "OSELTAMIVIR": 1.3533085908468847, "OXYBUTYNIN": 4.90426215409359, "PALIPERIDONE": 2.0147222200434007, "PANTOPRAZOLE": 1.4433195894876567, "PAXLOVID": 2.7840659761709534, "PEGASYS": 1.109370045383786, "PEGINTRON": 1.304469450508644, "PREGABALIN": 1.9437404626522865, "PRIALT": 4.004864637665608, "PROTELOS": 1.7823024335305109, "RANEXA": 2.508211412146361, "RANOLAZINE": 1.7718058435868989, "REAGILA": 1.5382133759890488, "REBIF": 1.2079113519261415, "REPAGLINIDE": 1.877273210058946, "RISPERIDONE": 3.192707645869039, "RIVASTIGMINE": 4.14339828602836, "SIFROL": 3.8568550732206095, "SODIUM": 4.934083684780522, "SOVALDI": 1.0212203044339114, "SPIRONOLACTONE": 1.4623840951122096, "STALEVO": 4.2149965511639325, "SYCREST": 1.2782195882602112, "TAMIFLU": 2.8511448160267747, "TASMAR": 5.669563911778029, "THALIDOMIDE": 1.0509162418462037, "TOVIAZ": 2.160341801823328, "TRISENOX": 1.2176533105386282, "TWYNSTA": 4.128622409048456, "VALDOXAN": 1.2602733193753188, "VELCADE": 1.0097936806534278, "VFEND": 2.358931423938808, "VIMPAT": 1.9021411427656216, "VORICONAZOLE": 1.83808589506885, "XTANDI": 1.8397638660519844, "XYREM": 1.973517296810137, "YESCARTA": 3.431549087613782, "ZONISAMIDE": 1.0045956933070326, "ZYPADHERA": 14.5999685816965, "ZYPREXA": 1.6083940405329844, "null": 1.7083504149770832}
\ No newline at end of file
+{"null": 2.9379778837632204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1951.json
index d3e3b24c73d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1951.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1951.json
@@ -1 +1 @@
-{"null": 2.259521014279036}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1952.json
index f5758341e0b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1952.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1952.json
@@ -1 +1 @@
-{"KAFTRIO": 625.8334028246551}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1953.json
index bbb04ab8401..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1953.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1953.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.0629393666227376, "APIXABAN": 4.782000810796671, "APTIVUS": 65.95198645740592, "ARAVA": 11.893907068626804, "ASPARAGINASE": 5.850741515615895, "BUDESONIDE": 2.2536665605845343, "BUPRENORPHINE": 4.119362281984643, "COMBIVIR": 18.19216385537997, "DESCOVY": 11.764958294092825, "EMTRICITABINE": 6.176010083784889, "KALETRA": 3.557491399146695, "KEPPRA": 1.9637281102539013, "LEVETIRACETAM": 4.2729897688882055, "OLANZAPINE": 1.3163175569936831, "SUBOXONE": 3.179312330708469, "null": 3.2704689230368134}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1954.json
index 83b1be44b35..7dff5c4c362 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1954.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1954.json
@@ -1 +1 @@
-{"MYCOPHENOLATE": 118.30553058830397, "null": 4.186724206320195}
\ No newline at end of file
+{"COMIRNATY": 1.815225818854253, "null": 1.1961012357127458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1955.json
index 66f8e96be5a..c7b7a8f9ec5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1955.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1955.json
@@ -1 +1 @@
-{"AVONEX": 717.2370049754162, "null": 2.1436111746495685}
\ No newline at end of file
+{"COMIRNATY": 6.252967840500616, "SPIKEVAX": 1.5638978504188406, "TOZINAMERAN": 1.258833419118729, "VAXZEVRIA": 0.4655964111214652, "null": 0.2268028616729129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1956.json
index 038ffcebd57..76005f9c027 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1956.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1956.json
@@ -1 +1 @@
-{"null": 6.340477532119922}
\ No newline at end of file
+{"null": 1.0060728874517513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1957.json
index 6ad75adf30b..31287b171c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1957.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1957.json
@@ -1 +1 @@
-{"null": 12.130823781918492}
\ No newline at end of file
+{"null": 2.88677152477758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1958.json
index 2f50ddd1d02..bd0fcab0146 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1958.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1958.json
@@ -1 +1 @@
-{"null": 6.779355604401743}
\ No newline at end of file
+{"AFINITOR": 1.1047322393785104, "APIDRA": 2.9421917405949385, "ARAVA": 0.3313945606232835, "CICLOSPORIN": 1.8875493266642545, "COMIRNATY": 0.8358510096643553, "CYMBALTA": 0.6744888858779243, "DOCETAXEL": 2.299763002844361, "ELIQUIS": 0.4592539473108438, "EVISTA": 9.090254398142012, "FASLODEX": 3.74193977162639, "FORSTEO": 1.5199691157585986, "GARDASIL": 1.119217609445151, "HUMALOG": 0.5537693301845283, "IBRANCE": 1.3955269009514135, "KISQALI": 5.230897797688006, "LANTUS": 0.7535387801762922, "METHOTREXATE": 1.870748347031159, "OLANZAPINE": 0.8484910367581053, "PEGASYS": 1.7773045074949765, "RIBOCICLIB": 36.2931240431416, "SIMPONI": 1.5515632902412064, "SPIKEVAX": 0.5189567750093548, "STELARA": 2.343467602962819, "TOZINAMERAN": 2.480283458762962, "VAXZEVRIA": 0.3785308132180545, "XELJANZ": 1.865400542582831, "XOLAIR": 3.008872779811941, "ZOSTAVAX": 1.9465874054031156, "ZYPREXA": 1.4270904943886304, "null": 1.2661401044252734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1959.json
index ae21f745a3d..1714e819205 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1959.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1959.json
@@ -1 +1 @@
-{"null": 11.966320698973249}
\ No newline at end of file
+{"COMIRNATY": 1.4504153795780397, "null": 1.2052203392349996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/196.json
index 0e757d988df..1d163ed20f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/196.json
@@ -1 +1 @@
-{"VAXZEVRIA": 11.701142339144964, "null": 1.0073536249268118}
\ No newline at end of file
+{"COMIRNATY": 1.324843234471384, "FAMPYRA": 14.197583487774455, "GARDASIL": 22.16354484870209, "MMRVAXPRO": 4.90569215227574, "NIMENRIX": 15.707706326410412, "SHINGRIX": 4.930235841435739, "SPIKEVAX": 0.7743399844515116, "TOZINAMERAN": 1.2275516422763058, "TWINRIX": 12.709154182156484, "VAXZEVRIA": 1.170824657433667, "null": 0.6512663106577651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1960.json
index 031a5281219..8f479b33d34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1960.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1960.json
@@ -1 +1 @@
-{"ALIMTA": 34.66324134269079, "AMIKACIN": 28.562420385438894, "AZACITIDINE": 18.133066178684484, "BUSULFAN": 13.573785602251816, "CELLCEPT": 4.829780306012806, "CICLOSPORIN": 2.907098437437819, "COMBIVIR": 11.70018866826262, "CYTARABINE": 15.793214999759323, "DOXORUBICIN": 10.629136231303564, "EMEND": 27.7043105783278, "KALETRA": 10.600956493436724, "KEPPRA": 1.4285855600473902, "KEYTRUDA": 1.8189596341507688, "KYMRIAH": 10.052785113625568, "MELPHALAN": 35.090598327140405, "METHOTREXATE": 3.298034464318245, "NEULASTA": 6.839830931939617, "SOLIRIS": 3.287029783163081, "TEMODAL": 35.36698485813653, "VYXEOS": 130.31133910646474}
\ No newline at end of file
+{"null": 5.079558024534284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1961.json
index c2928038de3..9774b865fac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1961.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1961.json
@@ -1 +1 @@
-{"ATOSIBAN": 1355.953495327631, "null": 1.0746098492797225}
\ No newline at end of file
+{"COMIRNATY": 0.2033866362031683, "FORSTEO": 6.69696218509038, "MEPOLIZUMAB": 13.881239992039015, "STELARA": 7.163221989481068, "XOLAIR": 7.519044519746774, "null": 0.8011875272178053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1962.json
index 87bef11825b..24a2b1bbbd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1962.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1962.json
@@ -1 +1 @@
-{"null": 1.8134317416246768}
\ No newline at end of file
+{"COMIRNATY": 5.738245500229154, "SPIKEVAX": 1.2229511626795342, "null": 0.5889108993755383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1963.json
index b0073669355..93593475d45 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1963.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1963.json
@@ -1 +1 @@
-{"NORVIR": 532.2562342398328, "null": 1.000143026188907}
\ No newline at end of file
+{"IBRANCE": 17.295565731531614, "MEPOLIZUMAB": 24.30935649074644, "null": 1.0732584294451135}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1964.json
index a262730180e..30298be1b48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1964.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1964.json
@@ -1 +1 @@
-{"null": 4.893452046139301}
\ No newline at end of file
+{"AFINITOR": 0.5037586122470279, "AIMOVIG": 1.9942317585487552, "BRINTELLIX": 0.7084684744820463, "CAPECITABINE": 1.612474473959811, "CHAMPIX": 0.3928095450599458, "CIMZIA": 0.1145729511023504, "CLOPIDOGREL": 0.1925848315338493, "COMIRNATY": 4.388032976085542, "COSENTYX": 0.3415476554527253, "CYMBALTA": 0.2885102931041057, "DOCETAXEL": 0.5267446602548344, "ELIQUIS": 0.0939913443102747, "ELLAONE": 21.78240385878443, "ESMYA": 2.988441351431604, "EVISTA": 1.115268549927738, "EVRA": 6.820687666695131, "FASLODEX": 1.0222531219964568, "FORSTEO": 0.5415838417548285, "GARDASIL": 0.2911040682276819, "IBRANCE": 0.960361186205577, "KAFTRIO": 2.4907684862540966, "LANTUS": 0.1070536679151438, "LYRICA": 1.0002102133512454, "METHOTREXATE": 0.648359398089426, "MODERNA": 3.6338927728874273, "NEULASTA": 0.8489463451574395, "OCRELIZUMAB": 0.9124925129792596, "OLANZAPINE": 0.6405412125278015, "OMALIZUMAB": 0.7675691799509693, "OVITRELLE": 20.400663249231133, "RINVOQ": 0.5636160145206655, "SHINGRIX": 0.3726810346163216, "SPIKEVAX": 1.8011076706472866, "STELARA": 0.1754663756965157, "SUTENT": 0.1282533779234498, "TOZINAMERAN": 2.880208961373623, "VAXZEVRIA": 0.7562287711947124, "XELJANZ": 0.1562652859508333, "XOLAIR": 0.4485222254214153, "ZOSTAVAX": 0.54860860615988, "ZYPREXA": 0.3025953505004307, "null": 0.6792483796744904}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1965.json
index 9ee6e07825b..72639bf8202 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1965.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1965.json
@@ -1 +1 @@
-{"ALISKIREN": 34.63964857021566, "null": 13.091129553352667}
\ No newline at end of file
+{"ARAVA": 34.65503553345888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1966.json
index 757c13fdadc..b9c53fd52dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1966.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1966.json
@@ -1 +1 @@
-{"COMBIVIR": 54.60220120505437, "IBUPROFEN": 10.501102855375102, "KEPPRA": 5.150417628381677, "NEVIRAPINE": 97.95426256205126, "null": 3.823610935757082}
\ No newline at end of file
+{"null": 2.801303591173798}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1967.json
index 0d6b33f1044..a9721816b5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1967.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1967.json
@@ -1 +1 @@
-{"null": 4.843626274582155}
\ No newline at end of file
+{"AZACITIDINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1968.json
index 8996e01e037..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1968.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1968.json
@@ -1 +1 @@
-{"null": 3.257312499748678}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1969.json
index b6f8782beb8..19cf1cae133 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1969.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1969.json
@@ -1 +1 @@
-{"COMBIVIR": 104.51399542322108, "ISENTRESS": 266.1014655127313, "null": 1.162750327229765}
\ No newline at end of file
+{"CHAMPIX": 0.655522642525233, "COMIRNATY": 5.127207492285477, "ELLAONE": 24.15111959547352, "EVISTA": 4.468531955798216, "SPIKEVAX": 1.548914851213315, "TOZINAMERAN": 3.0689639395958626, "VAXZEVRIA": 0.3464519983658292, "null": 0.5637518040723886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/197.json
index 6f526a79b8d..9a9346a215f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/197.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1575643831094289, "VAXZEVRIA": 1.6639837879517354}
\ No newline at end of file
+{"null": 1.514987313588726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1970.json
index 8b0bd33ad0f..1e9302e42f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1970.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1970.json
@@ -1 +1 @@
-{"null": 3.0519610348856903}
\ No newline at end of file
+{"AIMOVIG": 1.7239809115349756, "COMIRNATY": 3.967392029203338, "ELLAONE": 35.05443348359041, "GARDASIL": 0.9121006458830592, "PEGASYS": 0.3329964563328604, "SPIKEVAX": 1.533281179911533, "TOZINAMERAN": 1.3031444455563166, "VAXZEVRIA": 0.2690211098009352, "null": 1.1505842178364205}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1971.json
index cb79a1ef581..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1971.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1971.json
@@ -1 +1 @@
-{"null": 3.9817214600888367}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1972.json
index 9c34334cd0c..29ef95e38fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1972.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1972.json
@@ -1 +1 @@
-{"ATRIPLA": 4.272700865399618, "null": 2.7765584584197787}
\ No newline at end of file
+{"null": 8.776243808083176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1973.json
index c1ddd26a022..fee2dec4cd3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1973.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1973.json
@@ -1 +1 @@
-{"null": 1.4824843710479705}
\ No newline at end of file
+{"MMRVAXPRO": 51.02515718285372, "XYREM": 93.9842839999692, "null": 1.143704200284523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1974.json
index 37e666bcb64..1c7e3142c23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1974.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1974.json
@@ -1 +1 @@
-{"null": 1.0370531953463635}
\ No newline at end of file
+{"CELECOXIB": 25.438864669135505, "COMIRNATY": 0.2082851259882565, "CYMBALTA": 1.3575443272036378, "GARDASIL": 1.9725477293063245, "JARDIANCE": 2.699728266493602, "KALETRA": 7.010408486364128, "PEGASYS": 1.314842757087364, "SAXENDA": 10.363382417658302, "SPIKEVAX": 0.235972974898252, "SUTENT": 1.571268660831051, "TOZINAMERAN": 0.6467331359121319, "TRULICITY": 13.46262591544766, "VAXZEVRIA": 0.214581233879247, "null": 1.6046294040271405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1975.json
index 9fbfebc455e..93e49b50485 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1975.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1975.json
@@ -1 +1 @@
-{"COMBIVIR": 51.97426602649128, "null": 2.211141489254409}
\ No newline at end of file
+{"COMIRNATY": 1.0190267602975438, "null": 1.495406411419134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1976.json
index b5571507221..7c063da22a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1976.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1976.json
@@ -1 +1 @@
-{"APTIVUS": 5543.213819601852, "null": 1.0369890049532702}
\ No newline at end of file
+{"ACLIDINIUM": 69.76869441116006, "ADALIMUMAB": 0.2580785638111696, "AFINITOR": 1.2589929708412408, "ARAVA": 1.7377937168251147, "AZATHIOPRINE": 2.8596173233211712, "BUDESONIDE": 37.49314113453619, "CLOPIDOGREL": 1.5003331777383213, "COMIRNATY": 0.1551798076265768, "DEXAMETHASONE": 1.6204919318686064, "DUAKLIR": 150.2917806829923, "ELIQUIS": 0.3030855661383552, "ENTRESTO": 3.007565562611109, "ESOMEPRAZOLE": 7.646039111482623, "EXJADE": 3.128864064825811, "IBRANCE": 0.4848877177153625, "LEVOFLOXACIN": 2.6188524507329043, "MEPOLIZUMAB": 13.179252580808958, "NUCALA": 73.42234889322924, "OMALIZUMAB": 7.964347537033042, "PANTOPRAZOLE": 8.981495551403881, "PREGABALIN": 8.57011599054879, "ROTATEQ": 3.617247116940925, "SPIKEVAX": 0.1171316681865981, "SUTENT": 0.2909612163731357, "TOZINAMERAN": 0.1826099857991754, "VAXZEVRIA": 0.0360960459148704, "XOLAIR": 5.307364265968516, "ZOSTAVAX": 0.9830950466043112, "ZYPREXA": 0.6864778726471533, "null": 1.0731786919680368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1977.json
index f50da59ee25..3ef11e9d382 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1977.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1977.json
@@ -1 +1 @@
-{"null": 5.214905144521248}
\ No newline at end of file
+{"null": 0.7816763579197556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1978.json
index 134e206e8be..22476989ef0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1978.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1978.json
@@ -1 +1 @@
-{"null": 3.3592250169510494}
\ No newline at end of file
+{"null": 2.1207699682059635}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1979.json
index 8ff1279e31c..f3d421600e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1979.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1979.json
@@ -1 +1 @@
-{"null": 6.718693413790624}
\ No newline at end of file
+{"null": 1.7233708610319531}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/198.json
index 9c9c08214c0..a7ef15ae117 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/198.json
@@ -1 +1 @@
-{"SIMPONI": 394.952495009093}
\ No newline at end of file
+{"AZACITIDINE": 18.82969268886989, "COMIRNATY": 0.2142610687172646, "COSENTYX": 3.2904849637895905, "FILGRASTIM": 49.66079651931088, "NEULASTA": 19.18093011000357, "PEGASYS": 1.6833954525535046, "SPIKEVAX": 0.1246636974248329, "SPRYCEL": 6.632525313926249, "VAXZEVRIA": 0.1213150029585087, "null": 1.388555695196001}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1980.json
index a40f8eeeca2..62b9a41670c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1980.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1980.json
@@ -1 +1 @@
-{"null": 6.142822436292995}
\ No newline at end of file
+{"ABILIFY": 79.93635371845598, "CIMZIA": 6.121163519938034, "DEXAMETHASONE": 9.188598959031625, "GARDASIL": 11.104111477924382, "null": 1.5746041236873585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1981.json
index 4760e8c8fb3..1abad4c541d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1981.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1981.json
@@ -1 +1 @@
-{"KEPPRA": 10.300130062203094, "METHOTREXATE": 10.754129827194864, "null": 6.074003366358169}
\ No newline at end of file
+{"CHAMPIX": 36.41218226056184, "null": 1.7597236085888186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1982.json
index 886199c8d75..cff85100427 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1982.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1982.json
@@ -1 +1 @@
-{"null": 1.9021034470265756}
\ No newline at end of file
+{"null": 1.411306292743963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1983.json
index 08da05b1d03..f5ab4ff7777 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1983.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1983.json
@@ -1 +1 @@
-{"APTIVUS": 1569.8309245199737, "null": 2.263628304330927}
\ No newline at end of file
+{"null": 2.0196250187483145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1984.json
index d21d25573f9..d6a060ab6fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1984.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1984.json
@@ -1 +1 @@
-{"null": 3.018048574023795}
\ No newline at end of file
+{"MMRVAXPRO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1985.json
index 5d0555d516b..3a9d0cf08cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1985.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1985.json
@@ -1 +1 @@
-{"null": 5.8435418733158135}
\ No newline at end of file
+{"null": 2.118328606160788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1986.json
index 958942651d2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1986.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1986.json
@@ -1 +1 @@
-{"null": 1.4952445862083286}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1987.json
index 373f726295b..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1987.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1987.json
@@ -1 +1 @@
-{"null": 10.220279849209668}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1988.json
index dd81c4dc560..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1988.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1988.json
@@ -1 +1 @@
-{"KALETRA": 83.80333773959204, "null": 2.091528472676385}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1989.json
index e8c76b466bf..597b6312eaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1989.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1989.json
@@ -1 +1 @@
-{"null": 6.915373319994121}
\ No newline at end of file
+{"null": 1.3661856385304896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/199.json
index 45bf45f1493..821d8c740b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/199.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7836035970150972}
\ No newline at end of file
+{"ACTOS": 8.910389548435349, "AERIUS": 5.767660119085703, "ALIMTA": 2.690328480427259, "AMIKACIN": 5.658988385009125, "ARIXTRA": 13.558215731959434, "BRIDION": 3.698680034606853, "CANCIDAS": 10.534539441437744, "CASPOFUNGIN": 17.754355552551747, "CHAMPIX": 0.6441300244509839, "CLOPIDOGREL": 0.7077058480338961, "COMIRNATY": 0.0736602497160793, "CUBICIN": 5.903141674212228, "DEXAMETHASONE": 2.7201427815545425, "DIFICLIR": 21.42782478114413, "ELIQUIS": 0.4167295199711274, "ENOXAPARIN": 2.6237301834043785, "IBUPROFEN": 5.497423500303809, "INCIVO": 2.700346096947215, "JANUVIA": 1.2547663233873698, "KEPPRA": 1.73420862436612, "LEVETIRACETAM": 2.915635530766832, "LEVOFLOXACIN": 3.185896970238955, "MICARDIS": 1.8286719100187807, "MIDAZOLAM": 4.00719348000182, "NEXAVAR": 0.9953775677469648, "PANTOPRAZOLE": 5.208664628467326, "PLAVIX": 1.0369382806062717, "SPIKEVAX": 0.0398008935291186, "SPIRONOLACTONE": 11.069981200907966, "SUFENTANIL": 7.403251602720803, "TAMIFLU": 1.2242193151779783, "null": 6.344726001645394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1990.json
index bb0f10b430d..77122dd7c65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1990.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1990.json
@@ -1 +1 @@
-{"null": 1.7106632264816388}
\ No newline at end of file
+{"CELLCEPT": 19.83693831669584, "FORSTEO": 9.34636783690194, "null": 0.4663141781850524}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1991.json
index 886199c8d75..9567f6658b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1991.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1991.json
@@ -1 +1 @@
-{"null": 1.9021034470265756}
\ No newline at end of file
+{"CELLCEPT": 6.201636909363803, "COMIRNATY": 0.4219961115020885, "PANTOPRAZOLE": 47.211297697972405, "XELJANZ": 4.439763536856914, "null": 1.2684773290589382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1992.json
index 9377f637129..bb60fadb939 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1992.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1992.json
@@ -1 +1 @@
-{"COMBIVIR": 97.75788308783716, "null": 2.842235623081669}
\ No newline at end of file
+{"ELIQUIS": 6.167041829492858, "TICAGRELOR": 95.99923570525895, "null": 0.4744149287199816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1993.json
index 20f16985254..3d8b92d8d32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1993.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1993.json
@@ -1 +1 @@
-{"COMBIVIR": 91.38563586304085, "null": 2.1532386717524585}
\ No newline at end of file
+{"BUDESONIDE": 3.242763346309713, "CEFUROXIME": 729.1664017992144, "COMIRNATY": 0.4846767781424214, "DOVATO": 265.38219228543363, "ENTRESTO": 7.795532045927324, "GARDASIL": 2.169827093298637, "IBUPROFEN": 5.398674588874039, "LAMIVUDINE": 32.69532221930547, "MEPOLIZUMAB": 6.571802273538505, "NUCALA": 6.507246834829061, "PEGASYS": 1.2757144545749768, "SPIKEVAX": 0.1462796849050323, "SYNAGIS": 16.734990816283222, "VAXZEVRIA": 0.1424384024765903, "ZOSTAVAX": 3.1219795332320457, "null": 1.3228851593010194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1994.json
index 3bb38c88f90..db7aae691de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1994.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1994.json
@@ -1 +1 @@
-{"null": 5.924204865755229}
\ No newline at end of file
+{"null": 1.358446126336236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1995.json
index a96fc79966b..66a276bd256 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1995.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1995.json
@@ -1 +1 @@
-{"null": 4.745736607642976}
\ No newline at end of file
+{"COMIRNATY": 0.4623300014532849, "VAXZEVRIA": 0.6703887931042662, "null": 1.9845808154461388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1996.json
index 980f60bd0c5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1996.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1996.json
@@ -1 +1 @@
-{"null": 1.4013036081895904}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1997.json
index d3fdc6b338d..851600929ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1997.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1997.json
@@ -1 +1 @@
-{"null": 4.960764579439824}
\ No newline at end of file
+{"SKYRIZI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1998.json
index 77d82a819d8..a96a50dd56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1998.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1998.json
@@ -1 +1 @@
-{"null": 2.951985109345318}
\ No newline at end of file
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1999.json
index 04f83c0802b..02dd15dffca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1999.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/1999.json
@@ -1 +1 @@
-{"null": 2.119843710264686}
\ No newline at end of file
+{"ACLIDINIUM": 209.5070872558104, "BENRALIZUMAB": 60.17241970052928, "COMIRNATY": 0.0462506200626358, "GLYCOPYRRONIUM": 46.3832179390269, "KEPPRA": 2.347355146261094, "MEPOLIZUMAB": 97.31104283862877, "NUCALA": 18.42303380805844, "OMALIZUMAB": 7.327740282905513, "ONCASPAR": 33.35428060941311, "PANTOPRAZOLE": 27.153417060635853, "null": 1.065765733099291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2.json
index 931764198fa..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2.json
@@ -1 +1 @@
-{"null": 14.313118104890432}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/20.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/20.json
index 6f9c3e0ed66..ba42f65a7a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/20.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/20.json
@@ -1 +1 @@
-{"null": 2.395793498914625}
\ No newline at end of file
+{"COMIRNATY": 1.2120859930701025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/200.json
index fdffa6dd24c..45a072aa62a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/200.json
@@ -1 +1 @@
-{"null": 1.7203581838430817}
\ No newline at end of file
+{"ALEMTUZUMAB": 61.84202687329019, "AZATHIOPRINE": 6.136979254056884, "BUDESONIDE": 10.933763298807744, "BUSILVEX": 81.29891484665166, "BUSULFAN": 192.9920830055666, "CANCIDAS": 8.887920002633583, "CELLCEPT": 6.236591736188375, "CICLOSPORIN": 105.14005965496918, "CYTARABINE": 3.587126836832636, "DEXAMETHASONE": 4.022369304035951, "DOXORUBICIN": 11.27876069501697, "GANCICLOVIR": 8.473399684785521, "JAKAVI": 2.9754000907972125, "MELPHALAN": 83.38739046895434, "METHOTREXATE": 13.505922343214696, "MYCOPHENOLATE": 18.17143152520908, "RITUXIMAB": 1.748686105053702, "RUXOLITINIB": 10.048406242167546, "SOLIRIS": 2.4761277403317647, "TACROLIMUS": 9.556973829554424, "TEPADINA": 465.04008749833, "THIOTEPA": 40.98962384468704, "null": 0.3864095201326999}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2000.json
index 4f67fe2c4c1..f6b4067630a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2000.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2000.json
@@ -1 +1 @@
-{"null": 2.7893707053248438}
\ No newline at end of file
+{"null": 2.214696680158027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2001.json
index d08e30f644f..1020b1b9b27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2001.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2001.json
@@ -1 +1 @@
-{"null": 4.855175014559221}
\ No newline at end of file
+{"ALENDRONATE": 874.8399510733706, "APIXABAN": 82.83295771896186, "BENRALIZUMAB": 470.02037421264754, "BUDESONIDE": 11.928218076687228, "COMIRNATY": 0.0741730075928517, "ELIQUIS": 4.54938782289777, "FASENRA": 11.661531773123857, "KAFTRIO": 21.17992551075337, "MEPOLIZUMAB": 11.51529784322142, "NUCALA": 11.744724825086593, "OMALIZUMAB": 8.744701272398784, "SPINRAZA": 60.50588926688396, "XOLAIR": 3.392692037356375, "null": 0.4759282913815113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2002.json
index 05c7a2c781e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2002.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2002.json
@@ -1 +1 @@
-{"ISENTRESS": 373.7811060545165, "null": 4.577231279559243}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2003.json
index 742356f565c..f2a98eb4295 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2003.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2003.json
@@ -1 +1 @@
-{"null": 4.362431881502759}
\ No newline at end of file
+{"ACLIDINIUM": 160.32214726127918, "ALENDRONATE": 1041.1970068847506, "APIXABAN": 91.92047105923888, "BENRALIZUMAB": 615.7814374115536, "COMIRNATY": 0.1075758185938968, "DEXAMETHASONE": 12.021268484245391, "ELIQUIS": 5.155718149630832, "IBUPROFEN": 6.9248377859446, "MEPOLIZUMAB": 7.435105788490433, "NUCALA": 27.31883763457848, "null": 0.1767218698790214}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2004.json
index 7ae6f0b7e0d..5b35ab28094 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2004.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2004.json
@@ -1 +1 @@
-{"null": 3.076441908714847}
\ No newline at end of file
+{"ABATACEPT": 0.9349749193883578, "ACLIDINIUM": 141.1567129153049, "ADALIMUMAB": 7.462688861583084, "ADCIRCA": 7.228203542577359, "ALENDRONATE": 187.49994281058835, "AMIKACIN": 10.289576518451682, "ANORO": 8.991435254329664, "APIXABAN": 16.767859443156183, "ARANESP": 10.710581860649045, "ARAVA": 1.0515248291958113, "AVAMYS": 25.24680074471273, "BEDAQUILINE": 10.230507396783027, "BUDESONIDE": 20.217278246542453, "BUSULFAN": 11.17548476214774, "CANAGLIFLOZIN": 39.132790058294525, "CELLCEPT": 5.69280051752787, "CICLOSPORIN": 1.5160571818317283, "CLOPIDOGREL": 0.5615943801371026, "COMIRNATY": 0.067655136371733, "DUAKLIR": 152.05915273796617, "DULOXETINE": 3.06524566389532, "ELIQUIS": 1.2993839228572974, "FASENRA": 3.128964411946921, "FASLODEX": 2.5575364851562608, "FLUTICASONE": 17.044121340034994, "FORSTEO": 0.8335080331039881, "GANCICLOVIR": 6.120267609181379, "HIZENTRA": 3.5290916894420703, "HUMIRA": 1.1983544669381647, "HYDROCORTISONE": 7.162908448924911, "INVOKANA": 9.1888848388842, "LEVOFLOXACIN": 1.179255611810009, "MEPOLIZUMAB": 8.798508555583043, "METHOTREXATE": 0.940246334830788, "NUCALA": 13.93446598792309, "OCEAN": 179.1479124851229, "OMALIZUMAB": 12.984101242612734, "ORKAMBI": 13.967229476221178, "PANTOPRAZOLE": 2.513683129034652, "PEMBROLIZUMAB": 2.298775061160313, "PIRFENIDONE": 21.00905712958486, "RITUXIMAB": 2.3798972014282387, "SPIKEVAX": 0.0433999845265356, "TOZINAMERAN": 0.1713110969379799, "TRELEGY": 3.839627703993459, "VAXZEVRIA": 0.0604508059778898, "XELJANZ": 1.3000730593344372, "XOLAIR": 2.431348778599655, "null": 0.5524708579428327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2005.json
index 54cd560e674..7a3093f8ac6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2005.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2005.json
@@ -1 +1 @@
-{"APTIVUS": 547.0517563409115, "IBUPROFEN": 13.689689989294829, "KEPPRA": 3.949708801111435, "null": 3.078906456131421}
\ No newline at end of file
+{"ACLIDINIUM": 16.175340456847515, "ARAVA": 0.1873344893326683, "CELLCEPT": 3.074548275256527, "COMIRNATY": 0.0321743164737086, "HEMANGIOL": 88.93939424432632, "INFANRIX": 14.623405018478556, "KEYTRUDA": 0.9922488062068952, "LEVETIRACETAM": 2.238919700147162, "MENVEO": 52.93327123661008, "MEPOLIZUMAB": 2.048556564698317, "PEGASYS": 0.6961489345798952, "PEGINTRON": 1.3435649779246928, "ROTATEQ": 11.84755215591199, "SIMPONI": 1.6764025041577162, "SPINRAZA": 21.271557242793808, "STELARA": 0.8642540966222684, "SYNAGIS": 795.1510498098093, "SYNFLORIX": 778.7056142568129, "null": 0.8489304341279527}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2006.json
index 7c6ac17bd11..d3a4e5a57a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2006.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2006.json
@@ -1 +1 @@
-{"KEPPRA": 6.049825394161366, "null": 7.184964465072198}
\ No newline at end of file
+{"ALEMTUZUMAB": 151.47421677442998, "CICLOSPORIN": 30.95125260254786}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2007.json
index e52e2a45b3e..051db002724 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2007.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2007.json
@@ -1 +1 @@
-{"DARUNAVIR": 103.1479389574201, "null": 5.490266935379341}
\ No newline at end of file
+{"ABACAVIR": 0.6893662063809659, "ABATACEPT": 1.3732603932930956, "ABILIFY": 0.6450821071048239, "ACLASTA": 6.872073568617372, "ADALIMUMAB": 0.9744928733995268, "ADCIRCA": 1.4153141005550696, "ADEMPAS": 1.88590495764298, "AFINITOR": 0.8999284796126881, "AIMOVIG": 1.3600122655291944, "ALIMTA": 0.3300242439015833, "AMIKACIN": 1.1859780784818537, "AMINOSALICYLIC": 1.1243530193366085, "ANAKINRA": 1.1599138156064157, "ANORO": 2.2137365910200764, "APIDRA": 1.276573845441732, "APIXABAN": 0.3438696859246948, "ARANESP": 0.2459077733001599, "ARAVA": 0.5896281988377514, "ATRIPLA": 0.0237517305754498, "AUBAGIO": 1.5974195087752507, "AVAMYS": 0.5128935877746069, "AVANDIA": 0.2738255327373339, "BELIMUMAB": 4.369643278633794, "BENLYSTA": 3.954808607860557, "BEVESPI": 14.134157878480185, "BIKTARVY": 2.0708979039521043, "BOSULIF": 0.7490632709213919, "BUDESONIDE": 2.240629338108952, "BUPRENORPHINE": 0.5738902876763712, "BYDUREON": 1.0724063381652789, "BYETTA": 0.953203526226676, "CELECOXIB": 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1.4510492095358292, "PRIVIGEN": 1.1423491563558328, "RAPAMUNE": 1.578593327045855, "RASILEZ": 0.7964340687906118, "RELVAR": 4.113702591006953, "REMICADE": 2.550155345312408, "REVATIO": 3.490609259407106, "REVLIMID": 1.77972680433044, "RINVOQ": 1.7256847991276951, "RITUXIMAB": 1.6131866139970896, "ROACTEMRA": 2.9863536395319032, "ROTATEQ": 2.0553558395949034, "RUBRACA": 0.679522417985123, "SHINGRIX": 0.3678348593993603, "SIMPONI": 3.158091645401281, "SOLIRIS": 0.762030882315085, "SPIKEVAX": 0.1684320235431758, "SPINRAZA": 3.5488616282646763, "SPRYCEL": 1.2124845823864638, "STELARA": 1.7598742630768245, "SUBOXONE": 0.3802215364240452, "SUTENT": 0.4925018098064186, "SYNAGIS": 11.508272671282564, "SYNFLORIX": 12.842557096153971, "TAGRISSO": 0.7292454755861857, "TAMIFLU": 1.4686446280132672, "TASIGNA": 0.609805929307819, "THALIDOMIDE": 1.0124945901173643, "TOZINAMERAN": 0.2352864163705398, "TRACLEER": 2.36865969805664, "TRELEGY": 5.041169914926019, "TREMFYA": 2.706802533377124, "TRULICITY": 0.3124635126294307, "TWINRIX": 1.1080748483913794, "VAXZEVRIA": 0.0663462337355057, "VELCADE": 3.928902178751828, "VELTASSA": 1.8126422047066184, "VFEND": 0.3053445051205617, "VIAGRA": 0.5630237155831259, "VICTOZA": 1.0987248814697146, "VOTRIENT": 0.5300300011563934, "XARELTO": 1.4977075834098428, "XELJANZ": 5.286394890742678, "XOLAIR": 5.294202827290986, "XTANDI": 0.6536524340158995, "XYREM": 2.7452606514671865, "ZOMETA": 4.231717490299132, "ZOSTAVAX": 3.8394908703733215, "ZYPREXA": 1.6365045863775034, "null": 1.41952535846584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2008.json
index 746d52629a4..087f6fe1426 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2008.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2008.json
@@ -1 +1 @@
-{"APTIVUS": 1140.4637512091592, "null": 3.161596924363436}
\ No newline at end of file
+{"BUDESONIDE": 23.34454584816237, "COMIRNATY": 0.4410121766078413, "null": 0.7166936314389297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2009.json
index 7a9a620a044..4ab58f9c082 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2009.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2009.json
@@ -1 +1 @@
-{"null": 6.665797604505982}
\ No newline at end of file
+{"ARAVA": 1.2315008515444077, "BEDAQUILINE": 13.593554172192004, "COMIRNATY": 0.3463210770135768, "ENBREL": 14.566823397579366, "IBUPROFEN": 3.5857353558993936, "INSULIN": 12.57457495940387, "ISENTRESS": 20.967185771791083, "MEPOLIZUMAB": 4.885305470744494, "SPIKEVAX": 0.1640514345056925, "VAXZEVRIA": 0.0944731015093734, "XOLAIR": 3.5212798120886037, "ZOSTAVAX": 6.1105146797810885, "null": 1.5320699004745244}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/201.json
index 908723597b2..276e54da44c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/201.json
@@ -1 +1 @@
-{"null": 7.533176267607137}
\ No newline at end of file
+{"ALEMTUZUMAB": 73.30958306565203, "BASILIXIMAB": 46.38427783947407, "BUSULFAN": 200.39752740763296, "CANCIDAS": 28.6298501178443, "CELLCEPT": 4.663064861022632, "CICLOSPORIN": 107.1599394000188, "CYTARABINE": 5.789035605391401, "MELPHALAN": 64.2556300606548, "METHOTREXATE": 6.578053024986727, "MYCOPHENOLATE": 29.80960152005947, "THIOTEPA": 162.54282149464166, "null": 0.2048242406794522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2010.json
index 9800b119ada..b17078bb2c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2010.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2010.json
@@ -1 +1 @@
-{"null": 7.161141226200562}
\ No newline at end of file
+{"RELVAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2011.json
index 21d9c2f4dcc..77083f7713a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2011.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2011.json
@@ -1 +1 @@
-{"null": 8.97628505553988}
\ No newline at end of file
+{"COMIRNATY": 0.2925441945431258, "null": 0.9467645835678302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2012.json
index 6211486921e..056e5b4282b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2012.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2012.json
@@ -1 +1 @@
-{"null": 9.529860179479076}
\ No newline at end of file
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2013.json
index 744d799ea36..4403d54460c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2013.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2013.json
@@ -1 +1 @@
-{"null": 2.848173647013041}
\ No newline at end of file
+{"MIDAZOLAM": 116.7890562855435, "null": 1.4702359818995074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2014.json
index 975ec2af61f..6dede4261ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2014.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2014.json
@@ -1 +1 @@
-{"null": 6.423967744863229}
\ No newline at end of file
+{"DEXAMETHASONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2015.json
index 79d92a4fc76..9b9f1afc8d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2015.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2015.json
@@ -1 +1 @@
-{"null": 1.3193243928001126}
\ No newline at end of file
+{"null": 2.4797871277346024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2016.json
index ecaf05a7d20..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2016.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2016.json
@@ -1 +1 @@
-{"null": 10.133268100153286}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2017.json
index cd30ce600d0..265218857dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2017.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2017.json
@@ -1 +1 @@
-{"null": 7.597558212164849}
\ No newline at end of file
+{"BEDAQUILINE": 340.6205052791107, "null": 0.273434841251795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2018.json
index 40a91348d92..fcc0aabdc65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2018.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2018.json
@@ -1 +1 @@
-{"null": 6.858535438694921}
\ No newline at end of file
+{"COMIRNATY": 0.3598647161798396, "null": 1.170137265300678}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2019.json
index 02b639386e9..55883c45804 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2019.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2019.json
@@ -1 +1 @@
-{"null": 3.87893833691815}
\ No newline at end of file
+{"ALEMTUZUMAB": 17.33685683456892, "AMIKACIN": 6.186924017394556, "ANIDULAFUNGIN": 62.51483531482919, "ARAVA": 0.1747192464739539, "ASPARAGINASE": 82.87104268526888, "AXICABTAGENE": 37.950786354948434, "AZACITIDINE": 9.467144769669227, "AZATHIOPRINE": 3.187603736888649, "BASILIXIMAB": 21.782374444423755, "BORTEZOMIB": 10.512663891943696, "BUDESONIDE": 2.844801888297724, "BUSILVEX": 26.42179859007554, "BUSULFAN": 27.396401977610907, "CANCIDAS": 43.34668494295642, "CARMUSTINE": 16.246830411481817, "CASPOFUNGIN": 56.8478223562099, "CELLCEPT": 12.864963862675692, "CICLOSPORIN": 18.18871339254995, "CLADRIBINE": 25.875245747296983, "CYTARABINE": 15.747438688597022, "DEXAMETHASONE": 12.290064620483044, "DOXORUBICIN": 6.8681386893973855, "ELIQUIS": 0.4317769254583622, "EMEND": 12.45973788943276, "FASENRA": 2.831452740571564, "FILGRASTIM": 10.11119033701555, "GANCICLOVIR": 18.756910583858662, "IBRUTINIB": 20.694792117955508, "JAKAVI": 3.076214448069253, "KEYTRUDA": 0.4267918477985734, "LEVOFLOXACIN": 1.1823984618030894, "METHOTREXATE": 2.548404542499461, "MYCOPHENOLATE": 26.929603193258327, "NOXAFIL": 38.15860262220375, "OPDIVO": 2.852820722390136, "PEGINTERFERON": 1.8348054042910455, "POSACONAZOLE": 13.653872966793005, "RITUXIMAB": 4.472924831469649, "RUXOLITINIB": 12.569243110210758, "SOLIRIS": 2.0063333890840225, "TACROLIMUS": 15.253063593946726, "VEKLURY": 12.393097025086252, "VFEND": 28.842559591859, "VORICONAZOLE": 56.17052401359245, "XOLAIR": 0.9340354939676582, "null": 0.3847819470899425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/202.json
index 22ab41b97d6..028a6def84e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/202.json
@@ -1 +1 @@
-{"COMIRNATY": 4.613036758058735}
\ No newline at end of file
+{"ALEMTUZUMAB": 24.08664280295594, "BUSULFAN": 182.01213059481023, "CICLOSPORIN": 100.64234815671664, "CYTARABINE": 11.880416269822566, "MYCOPHENOLATE": 58.69114474023494, "null": 0.4024836116466618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2020.json
index 8cf864f6d6e..4a22f784d7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2020.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2020.json
@@ -1 +1 @@
-{"null": 3.720001388026715}
\ No newline at end of file
+{"ACLIDINIUM": 72.1848462799333, "APIXABAN": 24.58117118550698, "BUDESONIDE": 153.3986031525177, "MEPOLIZUMAB": 15.109387759252774, "NUCALA": 35.26784269707767, "OMALIZUMAB": 59.38924747516311, "ORKAMBI": 84.25134927806295, "XOLAIR": 7.645767157499886, "null": 0.2170828960355613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2021.json
index 982c2c5ab22..9e36c29470d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2021.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2021.json
@@ -1 +1 @@
-{"null": 10.342615192874046}
\ No newline at end of file
+{"null": 1.037185294654559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2022.json
index 20d2848000f..ec03097ca60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2022.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2022.json
@@ -1 +1 @@
-{"null": 2.226066968827946}
\ No newline at end of file
+{"ATOSIBAN": 287.70864136046146, "METHOTREXATE": 11.584725403687584, "SYNAGIS": 165.70738011159432, "null": 1.643670524306467}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2023.json
index f28038783c1..2062b785327 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2023.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2023.json
@@ -1 +1 @@
-{"null": 3.178702039398656}
\ No newline at end of file
+{"null": 1.119485076524022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2024.json
index f28038783c1..0d90e567e37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2024.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2024.json
@@ -1 +1 @@
-{"null": 3.178702039398656}
\ No newline at end of file
+{"AMIKACIN": 1.5871199998976375, "ANORO": 0.7964366375531299, "ARIXTRA": 3.66512353857739, "AVAMYS": 0.4770755115636363, "BENLYSTA": 0.870791533581342, "BRIDION": 55.95619925019741, "BRILIQUE": 0.8325093126979421, "BRIVIACT": 1.6080963460444382, "BUDESONIDE": 1.161111382548152, "CAELYX": 6.762408595565901, "CANCIDAS": 3.6155505404586346, "CAPECITABINE": 0.736410890144806, "CELECOXIB": 2.5304798082742943, "CHAMPIX": 0.2696242588077563, "CICLOSPORIN": 0.1123766549582461, "CIMZIA": 0.1255995840741719, "CLOPIDOGREL": 0.3024663676778142, "COAPROVEL": 1.016546841914443, "COMIRNATY": 0.2172412189860159, "DARZALEX": 9.632793347678753, "DEXAMETHASONE": 3.018925606549045, "ENBREL": 0.3056145017016968, "EXFORGE": 0.4920279664948519, "FASENRA": 2.5753978475074804, "FASLODEX": 1.1568151855868058, "FASTURTEC": 34.28335993372861, "FENTANYL": 9.849043075000914, "FLEBOGAMMA": 6.6132311800444725, "FORSTEO": 0.1762688759969495, "GARDASIL": 0.8233910161521225, "GAZYVARO": 4.758965037954392, "HERCEPTIN": 0.9733705714613484, "HYDROCORTISONE": 1.4271826617513736, "IBUPROFEN": 0.2672656858874483, "INCRUSE": 1.576885842836377, "KIOVIG": 3.6483714107038696, "LANTUS": 0.2210505905863283, "LEVOFLOXACIN": 1.0834477072593878, "MABTHERA": 1.8599868287085557, "MEPOLIZUMAB": 1.0763205094513104, "MIDAZOLAM": 10.828026404149185, "MMRVAXPRO": 0.3697028239152105, "NAGLAZYME": 7.0777177538668345, "NUCALA": 3.588070319856857, "OMALIZUMAB": 1.2416926327194298, "ONCASPAR": 20.408095103681894, "ORKAMBI": 5.628203537675902, "PEGASYS": 0.1515608279875012, "PEGINTRON": 0.3411480325299331, "PLAVIX": 0.2994607189514309, "PRIVIGEN": 4.147359201294235, "PROPRANOLOL": 2.304607318354291, "QARZIBA": 6.616126976354259, "RAPISCAN": 24.44311556697105, "RELVAR": 3.93423190087266, "REVATIO": 0.5935785545598123, "RIXATHON": 7.977436285500203, "ROACTEMRA": 0.5066623097952764, "SIMPONI": 0.2988665535993301, "SPIKEVAX": 0.0954463241054862, "SPINRAZA": 0.8215886649396088, "STELARA": 0.3083208122278638, "SUFENTANIL": 67.14935774584228, "SUGAMMADEX": 39.75421879118719, "SYNAGIS": 1.8547753926828248, "TAMIFLU": 0.6503773455040839, "TOBI": 71.21449624211903, "TOBRAMYCIN": 9.03659129074215, "TOPOTECAN": 42.62914140024444, "TOZINAMERAN": 0.7582438844123429, "TRELEGY": 0.5540306314198855, "VAXZEVRIA": 0.0752835538411419, "XELJANZ": 0.1220743241453486, "XOLAIR": 6.079094022198634, "ZOSTAVAX": 0.5322150807857039, "ZYPREXA": 0.1468456588818721, "null": 4.040721256937017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2025.json
index 764efea534b..d5b45ac4db9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2025.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2025.json
@@ -1 +1 @@
-{"null": 1.57529124026637}
\ No newline at end of file
+{"ANORO": 28.004217501239417, "SUFENTANIL": 74.50156901244907, "null": 7.23465621933372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2026.json
index d06ec386cec..55c71b15055 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2026.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2026.json
@@ -1 +1 @@
-{"null": 3.5716248259132075}
\ No newline at end of file
+{"COMIRNATY": 0.3860569303255287, "null": 3.3406826344503977}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2027.json
index f0150a1e6d6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2027.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2027.json
@@ -1 +1 @@
-{"null": 4.986923166446594}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2028.json
index ca9e4baa411..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2028.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2028.json
@@ -1 +1 @@
-{"null": 1.6633520118716214}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2029.json
index 5cfee8a9a70..57c8d2a8387 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2029.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2029.json
@@ -1 +1 @@
-{"null": 7.815999491952704}
\ No newline at end of file
+{"MIMPARA": 2998.3560143191157}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/203.json
index a49880711db..a929c76549e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/203.json
@@ -1 +1 @@
-{"COMIRNATY": 4.387298973774572, "SPIKEVAX": 6.494326833387717}
\ No newline at end of file
+{"ALEMTUZUMAB": 31.2462601006394, "ASPARAGINASE": 5.158804254737412, "AZACITIDINE": 11.475916850729137, "BUDESONIDE": 1.6831667915886317, "BUSILVEX": 118.4034805952871, "BUSULFAN": 311.49959762102907, "CICLOSPORIN": 104.12848710121092, "CYTARABINE": 7.730972200496694, "JAKAVI": 10.978294965445931, "KYMRIAH": 6.362211731247109, "METHOTREXATE": 10.952660047140624, "MYCOPHENOLATE": 35.37857387935901, "THIOTEPA": 191.7586418440809, "null": 0.2025709254401184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2030.json
index fbe007726b9..3d10e40cbce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2030.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2030.json
@@ -1 +1 @@
-{"null": 2.3242317539059485}
\ No newline at end of file
+{"null": 1.006633644640497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2031.json
index 4314ffa2c64..76f62a7caee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2031.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2031.json
@@ -1 +1 @@
-{"null": 1.016791246989776}
\ No newline at end of file
+{"ANTINEOPLASTICS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2032.json
index 6b023145317..301451c6de6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2032.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2032.json
@@ -1 +1 @@
-{"null": 1.009551223095855}
\ No newline at end of file
+{"null": 1.07247788368713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2033.json
index e78bdce14f9..06acf0167ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2033.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2033.json
@@ -1 +1 @@
-{"null": 1.4641793956652778}
\ No newline at end of file
+{"COMIRNATY": 0.109652260611625, "null": 5.937578699463038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2034.json
index e85722bc05a..e7debe24afe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2034.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2034.json
@@ -1 +1 @@
-{"null": 2.946876774685152}
\ No newline at end of file
+{"ABILIFY": 6.645779060586535, "ARIPIPRAZOLE": 10.679561069778636, "BRINTELLIX": 23.684387230913103, "CHAMPIX": 1.465442170881197, "CIMZIA": 0.916535036910197, "COMIRNATY": 0.1186910336433112, "CYMBALTA": 6.94688597340909, "GARDASIL": 2.714721268938394, "KEPPRA": 1.6660910542905565, "LATUDA": 17.753558010888593, "OLANZAPINE": 1.555102530476812, "SPIKEVAX": 0.2481908465823628, "TOZINAMERAN": 0.4063752591653405, "VAXZEVRIA": 0.2441985489592789, "XOLAIR": 1.4049383931255086, "ZYPREXA": 2.483291708957956, "null": 2.698687581873582}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2035.json
index 153e1504fdd..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2035.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2035.json
@@ -1 +1 @@
-{"null": 2.3778832419943305}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2036.json
index e286a1ad834..99de5d5aa63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2036.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2036.json
@@ -1 +1 @@
-{"null": 7.580088704520082}
\ No newline at end of file
+{"BUSULFAN": 44.90001464494112, "SOLIRIS": 72.90268676269388, "null": 1.0890244474159354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2037.json
index 5914adc88ac..4135cdf20db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2037.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2037.json
@@ -1 +1 @@
-{"CELLCEPT": 6.517876692859724, "ENTRESTO": 8.384737529573558, "OPSUMIT": 11.679755674874226, "TRACLEER": 33.590721466936046, "null": 1.56487052298974}
\ No newline at end of file
+{"VAXZEVRIA": 0.7578349565583234, "null": 0.5226776930269966}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2038.json
index 89a904895fd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2038.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2038.json
@@ -1 +1 @@
-{"ALISKIREN": 921.3235149663088, "null": 1.0414549261435924}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2039.json
index d4c56fded2a..64ea5612c62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2039.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2039.json
@@ -1 +1 @@
-{"null": 3.363071307471851}
\ No newline at end of file
+{"SIFROL": 236.9393873635864, "null": 1.7102131364662752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/204.json
index 46dfa335623..f74386f6b75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/204.json
@@ -1 +1 @@
-{"COMIRNATY": 4.426035853573776, "SPIKEVAX": 3.3978104585021973}
\ No newline at end of file
+{"null": 1.3419956826253077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2040.json
index 34e7a0795e8..6bc4dc27428 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2040.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2040.json
@@ -1 +1 @@
-{"null": 2.5322569562112758}
\ No newline at end of file
+{"ENOXAPARIN": 162.20945636538409, "null": 1.684094227665661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2041.json
index 7b9a914e041..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2041.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2041.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2042.json
index 93900b5de61..4cf184e33a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2042.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2042.json
@@ -1 +1 @@
-{"null": 2.635913811003926}
\ No newline at end of file
+{"AVANDIA": 4.871043275993024, "COMIRNATY": 0.1019178549786847, "null": 3.629585582343146}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2043.json
index 07cfb77a211..c0ec816d0bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2043.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2043.json
@@ -1 +1 @@
-{"null": 1.4474562358188392}
\ No newline at end of file
+{"null": 1.3736211540681045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2044.json
index 5f99fe290d8..4117957029e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2044.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2044.json
@@ -1 +1 @@
-{"null": 3.01474544380596}
\ No newline at end of file
+{"AFINITOR": 2.113178531711932, "APROVEL": 8.415018469696934, "AVANDIA": 5.154379714731715, "CLOPIDOGREL": 2.6993710175693995, "COMIRNATY": 0.366211361539972, "DELAMANID": 13.986871751063044, "EFAVIRENZ": 9.554385342338607, "ENTRESTO": 11.71035244551503, "FASLODEX": 2.128635403746267, "FENTANYL": 3.318787097040345, "IRBESARTAN": 13.32397131700644, "JANUMET": 1.8244979129489225, "JANUVIA": 1.6401199260849315, "KEPPRA": 0.9958289410930344, "LEVOFLOXACIN": 1.7925263971665908, "NOT": 7.8619749980933635, "RASILEZ": 8.672868725766053, "SPIKEVAX": 0.3051807838018582, "SPIRONOLACTONE": 23.00134101042033, "TOZINAMERAN": 0.2402370714056032, "VAXZEVRIA": 0.0866693239817164, "ZOSTAVAX": 1.6500921835268136, "ZYPREXA": 1.8364738686588045, "null": 1.9728313963559585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2045.json
index d7301f7a323..40103b7e6d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2045.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2045.json
@@ -1 +1 @@
-{"null": 21.41468065131837}
\ No newline at end of file
+{"ABILIFY": 2.436652751439532, "ARIPIPRAZOLE": 2.67589587059719, "AVANDIA": 5.488581106330056, "BEDAQUILINE": 6.514673507977062, "CLOPIDOGREL": 0.8473584642192883, "COMIRNATY": 0.3817672075597342, "FENTANYL": 2.2233421573793657, "GARDASIL": 0.949768646053781, "IRBESARTAN": 9.853010291316506, "JANUMET": 2.052495986905681, "JARDIANCE": 0.925193817327084, "OLANZAPINE": 2.772685109256989, "SPIKEVAX": 0.3200408301313012, "TOZINAMERAN": 0.3623475038054196, "VAXZEVRIA": 0.0913811331703607, "ZOSTAVAX": 0.9726255138649668, "ZYPREXA": 2.09361369094556, "null": 2.383396433848416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2046.json
index c0b255f5493..e838cc8f8ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2046.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2046.json
@@ -1 +1 @@
-{"BRILIQUE": 7.081569906454659, "CLOPIDOGREL": 10.014906575958348, "ELIQUIS": 8.348533677429831, "ENOXAPARIN": 4.901895835345565, "EYLEA": 21.510055283823213, "LIXIANA": 10.076311803848563, "PLAVIX": 8.764617160620695, "SUTENT": 1.2763360441874343, "TASIGNA": 1.435050922398511, "TICAGRELOR": 10.210196166291176, "TOZINAMERAN": 1.027161827998768, "VAXZEVRIA": 1.3556358196720488, "VIAGRA": 2.417908368677417, "null": 1.2067600475045723}
\ No newline at end of file
+{"ABATACEPT": 16.787359344727705, "ARAVA": 55.159018252257326, "null": 0.348555438337358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2047.json
index f84c4a1b868..f7cacd9341f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2047.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2047.json
@@ -1 +1 @@
-{"AZOPT": 43.730374107185526, "BEOVU": 12.886013369570108, "CICLOSPORIN": 1.2737082756243576, "DEXAMETHASONE": 1.3348525368958724, "EYLEA": 8.680281110325517, "IBUPROFEN": 2.1056854367274265, "LEVETIRACETAM": 2.1527398136336577, "LEVOFLOXACIN": 3.310148512940972, "MMRVAXPRO": 2.807183475292194, "NEVANAC": 29.338215224253343, "NEVIRAPINE": 21.831025787312583, "ONCASPAR": 13.5280991503291, "TAMIFLU": 2.0502722129183675, "null": 3.261581592645924}
\ No newline at end of file
+{"CICLOSPORIN": 24.704663174819707, "null": 2.3409756031485403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2048.json
index ad8dadb37ee..0e3f2a5bc2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2048.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2048.json
@@ -1 +1 @@
-{"null": 1.5515645197570922}
\ No newline at end of file
+{"null": 1.0567857957019913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2049.json
index c0f1199e0db..6071ce68039 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2049.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2049.json
@@ -1 +1 @@
-{"null": 3.5577112047649333}
\ No newline at end of file
+{"CELLCEPT": 38.84832194107833, "CICLOSPORIN": 17.50822994358182, "CYTARABINE": 30.92677999308082, "null": 0.2727288678000152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/205.json
index 9deef985af7..16393d47cc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/205.json
@@ -1 +1 @@
-{"null": 1.5239202029864345}
\ No newline at end of file
+{"null": 1.5399766571559377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2050.json
index 3acf535d865..3951627be7a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2050.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2050.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 64.68798546849972}
\ No newline at end of file
+{"SODIUM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2051.json
index 4a47d39ac18..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2051.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2051.json
@@ -1 +1 @@
-{"null": 2.8166190633714923}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2052.json
index 50c437ba29f..55d844dc8cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2052.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2052.json
@@ -1 +1 @@
-{"ABILIFY": 1.888775829977405, "ALIMTA": 4.653762108630027, "AP": 236.7319672946979, "ARIPIPRAZOLE": 1.6389505818628465, "CETUXIMAB": 8.907819543092893, "COSENTYX": 3.196776240243239, "COTELLIC": 4.028240801491386, "CRIXIVAN": 3.1923777336566554, "DEXAMETHASONE": 1.0008887093351406, "ENTYVIO": 1.192123785003533, "ERBITUX": 8.379775585948028, "EYLEA": 2.224855414779106, "FASENRA": 1.5485410583862071, "GLIBENCLAMIDE": 4.372939724984836, "HALAVEN": 2.4274476494459893, "INFANRIX": 6.216057018745153, "IPILIMUMAB": 1.1452381777538636, "IRESSA": 1.782039051083561, "IRINOTECAN": 2.4261047855747604, "LAMIVUDINE": 2.0377013114823663, "MEKINIST": 1.05243481822229, "METHOTREXATE": 1.0467460497251628, "MMRVAXPRO": 18.754667283918312, "NEVANAC": 8.400171226177648, "NEVIRAPINE": 8.519764558896153, "NIMENRIX": 1.2894710067211332, "NORVIR": 2.0567808723047305, "OPDIVO": 1.0028561243129428, "PANITUMUMAB": 14.84816037599784, "PEMBROLIZUMAB": 2.2779569168929434, "PREVENAR": 5.461493573092191, "RINVOQ": 1.8722396883329355, "ROACTEMRA": 2.706036538087259, "ROTATEQ": 1.80845497800706, "SIMPONI": 1.2529166330374626, "STELARA": 1.1760894363534042, "SUFENTANIL": 4.023517925245391, "SYNAGIS": 2.320389870670283, "TAGRISSO": 2.064826211216725, "TAMIFLU": 2.129218440977306, "TASIGNA": 1.3195173801407254, "TOBRAMYCIN": 4.69846648538013, "TWINRIX": 1.865195572979876, "VECTIBIX": 13.375080194716892, "VIRAMUNE": 7.450527180532714, "XOLAIR": 1.092396522188849, "YERVOY": 3.0194215175323427, "ZELBORAF": 4.289907678071463, "ZIAGEN": 9.77045401966187, "ZOSTAVAX": 1.84094205293824, "null": 1.6716907701624946}
\ No newline at end of file
+{"null": 1.4568942704774168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2053.json
index e084d0871a6..a34d7da61ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2053.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2053.json
@@ -1 +1 @@
-{"ANORO": 501.9557273661868, "APIXABAN": 79.75215614792687, "AZATHIOPRINE": 26.38942248531261, "ZOSTAVAX": 3.931144467832018}
\ No newline at end of file
+{"COMIRNATY": 0.1197564243402316, "SUTENT": 2.167730588378632, "null": 4.642201039933801}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2054.json
index c134be4d039..977ca89d62a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2054.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2054.json
@@ -1 +1 @@
-{"ZOSTAVAX": 21.88456741933103}
\ No newline at end of file
+{"null": 1.2685970754618725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2055.json
index 985ef452961..e485ccdaf65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2055.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2055.json
@@ -1 +1 @@
-{"GARDASIL": 7.184985016512057, "PEGINTRON": 11.53237051439903, "null": 1.030760515887358}
\ No newline at end of file
+{"LEVEMIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2056.json
index 97172943dba..d178f7507df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2056.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2056.json
@@ -1 +1 @@
-{"GARDASIL": 2.911629417832572, "OLANZAPINE": 9.429362502258442, "ZYPADHERA": 23.833402679072265, "null": 2.6895067915123465}
\ No newline at end of file
+{"COMIRNATY": 0.2779283649677531, "SUTENT": 6.895188913261053, "VAXZEVRIA": 0.2547990389842178, "null": 3.640712485759992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2057.json
index 7806386e003..84ed813b1cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2057.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2057.json
@@ -1 +1 @@
-{"1": 17.649962607021507, "ABACAVIR": 6.056210504784032, "ABRAXANE": 1.220720319390301, "ADCETRIS": 3.403794099978616, "ADEMPAS": 1.8861208063183488, "AFINITOR": 1.5019138165828292, "AIMOVIG": 15.590454420594584, "ALECENSA": 8.640128677945562, "ALIGN": 12.740764314155877, "ALIMTA": 1.93864642588466, "ALL": 1.046730139537566, "ALOXI": 2.518250336260491, "AMBROXOL": 20.514520952899133, "AMINOSALICYLIC": 6.48903639271728, "AMLODIPINE": 17.15046578978299, "APIXABAN": 1.7397547347535116, "APROVEL": 1.4501528968061033, "ARANESP": 9.739752824389711, "ASENAPINE": 2.912677411857183, "ATEZOLIZUMAB": 8.10373240605348, "AVAMYS": 3.455575285974829, "AVASTIN": 2.2389320076574117, "AXITINIB": 1.1681888895616608, "AZILECT": 1.736649814925246, "BAVENCIO": 1.183587354240971, "BETMIGA": 7.540772653140951, "BEVACIZUMAB": 1.3145561907327652, "BEXTRA": 1.812257044225681, "BLINCYTO": 2.07882795585028, "BOSULIF": 2.982985568918867, "BRAFTOVI": 1.7654881414481298, "BRINTELLIX": 2.6762746457250555, "BRIVIACT": 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\ No newline at end of file
+{"COMIRNATY": 1.02102748127208, "TOZINAMERAN": 2.2475862207576998, "VAXZEVRIA": 1.7984163131250197, "null": 0.263833537205777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2058.json
index 85fea4bddd7..8f89081a40c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2058.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2058.json
@@ -1 +1 @@
-{"COVID19": 2.946861043036056}
\ No newline at end of file
+{"COMIRNATY": 0.9842287761950388, "VAXZEVRIA": 0.5702398076120966, "null": 1.1957608615316524}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2059.json
index 581ed1ab0d3..8f7908c7216 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2059.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2059.json
@@ -1 +1 @@
-{"null": 5.872848245864311}
\ No newline at end of file
+{"ABASAGLAR": 0.901405770198968, "ABATACEPT": 0.1335629495274067, "ABILIFY": 1.0359523641786677, "ABRAXANE": 2.8588241058322024, "ADALIMUMAB": 0.1085385846527166, "AERIUS": 0.9187600399418624, "AFINITOR": 0.5927112999545647, "AIMOVIG": 0.955914501208868, "ALDARA": 2.162931599365788, "ALEMTUZUMAB": 0.3561832669230169, "AMINOSALICYLIC": 0.4509543165196028, "APIDRA": 0.9203847818159682, "APIXABAN": 12.925521378678692, "APROVEL": 0.9943578848741208, "ARAVA": 0.1277887528781122, "AUBAGIO": 2.3965811461273714, "AVAMYS": 0.4232502977552643, "AZATHIOPRINE": 0.3496882010224403, "BENLYSTA": 1.2447821815701017, "BIKTARVY": 1.0605550104896928, "BONVIVA": 1.1214231757495587, "BRILIQUE": 0.3309558310089152, "BRINTELLIX": 1.0331327111670772, "BUPIVACAINE": 2.494394868292706, "BUPRENORPHINE": 0.3481906844479316, "BYDUREON": 0.4675381814054075, "CABOMETYX": 0.370446037008737, "CAELYX": 0.6488481761751446, "CELECOXIB": 1.2960389814014064, "CELLCEPT": 0.1753666429152767, "CHAMPIX": 0.3078552959098111, "CICLOSPORIN": 0.5158730577169782, "CIMZIA": 0.5537351502954643, "CLOPIDOGREL": 0.3495226805819248, "COMIRNATY": 1.3366298993949066, "CONTRAST": 4.498329746871734, "COSENTYX": 1.5749169792373696, "CYMBALTA": 0.8880484852520691, "DEXAMETHASONE": 0.2606729795057856, "DULOXETINE": 0.3312424305617059, "ELIQUIS": 0.996103493226862, "EMEND": 1.501910855185215, "ENBREL": 1.0656030828515102, "ENTRESTO": 0.202780590907324, "ENTYVIO": 0.6660741367307029, "ERENUMAB": 1.9615820535183528, "ESBRIET": 0.7551391441620972, "ESOMEPRAZOLE": 0.7990536877883877, "EVISTA": 0.802075222856695, "EXFORGE": 0.901058955805424, "EXJADE": 0.2445911062961395, "FAMPYRA": 1.3364220269547005, "FASENRA": 0.491143267104511, "FASLODEX": 1.2778554289814976, "FENTANYL": 0.177761476214056, "FIASP": 1.253663000763556, "FIRDAPSE": 1.253027945122042, "FORSTEO": 1.4783527056440913, "FORXIGA": 0.8369502985522554, "GARDASIL": 0.9231048091843422, "HARVONI": 0.404806031777145, "HERCEPTIN": 0.6670037018458479, "HIZENTRA": 1.1220535785931645, "HUMALOG": 0.4274373232208447, "HUMIRA": 0.5212640491870978, "HYDROCORTISONE": 3.0969693038861887, "IBRANCE": 0.8901281060242625, "IBUPROFEN": 0.4802830497765412, "IMIQUIMOD": 4.472287690951847, "INCIVO": 0.2810281517045276, "INLYTA": 0.4915207371284881, "INSULIN": 0.2697421284527108, "IRBESARTAN": 0.7226079881274774, "JAKAVI": 0.3435113204639831, "JANUMET": 0.4345766549761127, "JANUVIA": 0.4497210664835123, "JARDIANCE": 0.6800094279494796, "KEPPRA": 0.2344234911362088, "KESIMPTA": 1.36426041850766, "KEYTRUDA": 0.1540319851193695, "LANTUS": 1.046409483707763, "LEMTRADA": 0.4476705308802697, "LEVEMIR": 0.4752335006859348, "LEVOFLOXACIN": 0.8648479451633032, "LIXIANA": 0.4512731876137684, "LYNPARZA": 0.3676588548210884, "LYRICA": 2.315353011001159, "MEKINIST": 0.253374463030437, "MEPOLIZUMAB": 1.829862120100406, "METHOTREXATE": 0.2398104592863289, "MICARDIS": 0.3201670610401673, "MODERNA": 0.3720916291732849, "NEULASTA": 0.5456990575116761, "NEXAVAR": 1.0163434823788862, "NINLARO": 0.8226321989016692, "NOT": 0.6254085150883028, "NUCALA": 0.611801910994206, "OCRELIZUMAB": 1.0007127706499903, "OLYSIO": 1.1647968651704157, "OMALIZUMAB": 2.659606123404889, "OPSUMIT": 0.2479067581176307, "OPTIMARK": 22.480802468608324, "OXYBUTYNIN": 1.06705587305285, "PANTOPRAZOLE": 0.3442807862320375, "PEGASYS": 0.8821868703645537, "PEGINTRON": 0.6149274788382962, "PLAVIX": 0.3039916666892704, "PLEGRIDY": 1.0589317355249437, "PREGABALIN": 0.4899370680037076, "PRIVIGEN": 0.4315678791301842, "QUTENZA": 29.231661017085308, "RIBAVIRIN": 0.279655580811617, "RINVOQ": 0.5991731054090612, "RITUXIMAB": 0.3359890578698842, "ROACTEMRA": 0.6474850868739997, "SAXENDA": 0.5767381557771772, "SHINGRIX": 3.459232501789458, "SIMPONI": 0.5163328141191487, "SOLIRIS": 0.1821282044652386, "SPIKEVAX": 1.04232161252882, "SPRYCEL": 0.2791571337673029, "STELARA": 0.488561343627067, "STIVARGA": 0.8305798484349829, "SUBOXONE": 0.2245603886541129, "SUTENT": 1.371612231426177, "TAMIFLU": 0.5099314069682357, "TASIGNA": 0.4397814425387186, "TOUJEO": 0.9903860328643466, "TOVIAZ": 0.4327405130797206, "TOZINAMERAN": 2.0771455928455937, "TREMFYA": 0.4803972264755703, "TRULICITY": 0.2910054635682202, "TRUVADA": 0.0552073554931109, "TWINRIX": 1.291331378239469, "VAXZEVRIA": 0.958430276640416, "VFEND": 0.1845045059542046, "VIAGRA": 0.3084037983805143, "VOTRIENT": 0.4669509865047229, "XELJANZ": 0.8547419336283649, "XOLAIR": 1.1989064474244129, "XTANDI": 0.6308847978902614, "XYREM": 0.6379949447208609, "ZOSTAVAX": 0.6131462506445056, "ZYPREXA": 0.0839933921428023, "null": 1.0121679108581012}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/206.json
index 03b778baaf1..212e462aff1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/206.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"ABACAVIR": 0.8154541303171614, "ALLI": 85.13577901866176, "ARAVA": 0.4132742864608217, "ATRIPLA": 0.0805661074158129, "AVANDIA": 0.5913149180828773, "AVASTIN": 1.151789280211846, "AZATHIOPRINE": 2.640068957236476, "BARACLUDE": 8.85580735725713, "BEVACIZUMAB": 1.7285136816002076, "BUDESONIDE": 0.4063949515415359, "BUSULFAN": 2.777938423503902, "CANCIDAS": 3.8503781547884985, "CICLOSPORIN": 0.4974246404279876, "CLOPIDOGREL": 0.6217288611924622, "COMIRNATY": 0.04212775117277, "CYMBALTA": 0.5247826921958062, "CYTARABINE": 1.6436637464135129, "DEXAMETHASONE": 0.9171992646303222, "DOXORUBICIN": 7.77583781712053, "DULOXETINE": 2.0606675511569503, "ELIQUIS": 0.84456013265325, "ENOXAPARIN": 2.5794787687430416, "ENTECAVIR": 10.783547155231188, "ENTRESTO": 0.9393867463070767, "EXJADE": 2.6364694038824537, "EXVIERA": 12.357646321432814, "FASLODEX": 2.549841086503624, "FEBUXOSTAT": 7.108204797090248, "FENTANYL": 2.4525371219519623, "HARVONI": 2.697762741304837, "IBUPROFEN": 5.198536209734825, "JANUVIA": 0.7420029921160086, "KALETRA": 3.1794869466521987, "KEPPRA": 1.923259826142455, "KEYTRUDA": 0.6972707123000331, "LACOSAMIDE": 4.500674491304552, "LAMIVUDINE": 11.273679665831851, "LEVETIRACETAM": 4.581103047247436, "LEVOFLOXACIN": 1.9952152476123, "LOPINAVIR": 7.007636297572402, "MERCAPTOPURINE": 7.286252685833618, "METHOTREXATE": 1.2877925112722672, "MULTAQ": 5.140314491514364, "NEXAVAR": 3.21338627833468, "OLANZAPINE": 1.909626169824309, "OLYSIO": 8.180619852071928, "ONCASPAR": 4.943831422580731, "PANTOPRAZOLE": 2.5668719692431528, "PEGASYS": 1.169510301376432, "PEGINTRON": 1.2690740249727794, "PLAVIX": 0.6637968765318469, "RITUXIMAB": 6.375628584151174, "ROACTEMRA": 0.9433620789433372, "SPIKEVAX": 0.034966582395623, "STIVARGA": 3.914022727578105, "SUBOXONE": 0.7266657261731025, "SUNITINIB": 16.54972415045368, "SUTENT": 1.4857269656577894, "TAMIFLU": 3.425741380328815, "TRACLEER": 0.8153348696482778, "TRUVADA": 0.2557500443390967, "VAXZEVRIA": 0.0182026765071949, "VFEND": 1.688609963546209, "VIRAMUNE": 18.76939921792588, "VORICONAZOLE": 2.5856632098605936, "VOTRIENT": 1.6348673855052955, "ZYPREXA": 0.3722264643575529, "null": 2.3612393328600025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2060.json
index a05469625b4..ae72533c2a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2060.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2060.json
@@ -1 +1 @@
-{"null": 1.945806859998348}
\ No newline at end of file
+{"COMIRNATY": 0.7212847302734268, "VAXZEVRIA": 0.2269634097292256, "null": 2.856325427112971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2061.json
index 7d3d1269166..a5f00b777ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2061.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2061.json
@@ -1 +1 @@
-{"null": 1.431887213883862}
\ No newline at end of file
+{"CHAMPIX": 13.019035498520289, "COMIRNATY": 1.509599953899257, "SPIKEVAX": 0.6682645775524059, "VAXZEVRIA": 0.981276373558182, "null": 0.7900303976193859}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2062.json
index d513498ef12..67ac27729fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2062.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2062.json
@@ -1 +1 @@
-{"ABACAVIR": 12.615542890687712, "ABATACEPT": 17.164194004458192, "ACETAMINOPHEN": 18.46441229360237, "ADALIMUMAB": 18.234577497796696, "AIMOVIG": 2.795384371498977, "AMINOSALICYLIC": 1.950182087227108, "ANAKINRA": 21.662319919061044, "APREMILAST": 15.695889562123552, "APREPITANT": 19.48181001863859, "ARAVA": 32.50095198601979, "AZATHIOPRINE": 1.7651867770313423, "CERTOLIZUMAB": 5.625805171944957, "CHLORHEXIDINE": 12.315800279230569, "CIMZIA": 9.139654051733412, "CLOPIDOGREL": 2.2802936992207106, "COSENTYX": 1.0300899430474062, "DESLORATADINE": 1.5956761055542763, "ELIQUIS": 1.39824187150674, "ENBREL": 13.452831282530967, "ENTRESTO": 6.692959633049774, "ERELZI": 3.327097393474024, "ERENUMAB": 2.3810260812840407, "ETANERCEPT": 1.6491594488441716, "HUMIRA": 2.3824559836587555, "LEFLUNOMIDE": 1.788845695133521, "LIXIANA": 1.2852101797798363, "MYCOPHENOLATE": 1.1247725282186962, "ORENCIA": 3.857741509304713, "PAXLOVID": 5.171335477168774, "PROPRANOLOL": 1.2560427525647226, "RITUXIMAB": 2.045184107753752, "RIVAROXABAN": 1.7007768113439945, "SELINCRO": 43.16914042468668, "TACROLIMUS": 2.7845585326378406, "TELMISARTAN": 1.054694876289065, "XARELTO": 1.343952823513223}
\ No newline at end of file
+{"QUTENZA": 484.92340337903954, "null": 2.343809814796749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2063.json
index 8bbd348ce6e..577ea05a080 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2063.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2063.json
@@ -1 +1 @@
-{"ANORO": 16.008023053548527, "ARAVA": 3.093960960985429, "CLOPIDOGREL": 4.03797702723031, "COSENTYX": 9.612736943103892, "null": 3.4772974339163}
\ No newline at end of file
+{"ADALIMUMAB": 23.40416026595542, "QUTENZA": 607.7326657258338, "TOZINAMERAN": 0.6281793002473431, "null": 1.2003945504622255}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2064.json
index df162ca7a0d..f7639f79f4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2064.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2064.json
@@ -1 +1 @@
-{"CIMZIA": 8.904888839553843, "null": 3.5446371750639747}
\ No newline at end of file
+{"null": 1.9304025138975545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2065.json
index e57c29622a8..d1afb413448 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2065.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2065.json
@@ -1 +1 @@
-{"ADALIMUMAB": 4.413695800156847, "ARAVA": 4.170106012900478, "SIMPONI": 18.77306757272398, "STELARA": 23.572072984803462, "ZOSTAVAX": 21.664203187001128}
\ No newline at end of file
+{"COMIRNATY": 0.885961271972709, "METHOTREXATE": 25.01833095489216, "null": 0.4034495627047233}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2066.json
index 61c2b62979a..8fc7c67389e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2066.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2066.json
@@ -1 +1 @@
-{"ABACAVIR": 16.890621327361735, "ABILIFY": 7.9707485302043395, "ARAVA": 2.624520251869501, "ENBREL": 46.46160808954346, "null": 1.7708995584084468}
\ No newline at end of file
+{"ABACAVIR": 47.20459823749535, "ABATACEPT": 30.314246862932205, "ABILIFY": 1.83969297974722, "ADALIMUMAB": 30.928027513727223, "AFINITOR": 0.4213160759520375, "AIMOVIG": 3.139894883279283, "AMINOSALICYLIC": 6.197631907260624, "APIXABAN": 0.7648654249698774, "APREMILAST": 16.22235912199517, "APREPITANT": 6.845969820040452, "ARAVA": 4.767680964386109, "CELECOXIB": 2.539527983175564, "CERTOLIZUMAB": 15.908669035902443, "CICLOSPORIN": 0.2228530274860716, "CIMZIA": 1.8053000158001429, "COMIRNATY": 0.4332246685288157, "COSENTYX": 3.793975043341068, "CYMBALTA": 2.3551921786126364, "DULOXETINE": 2.760632553521189, "ELIQUIS": 0.4595913778956724, "ENBREL": 2.160150352365332, "FASENRA": 1.0351352719563645, "FASLODEX": 0.5251831032285202, "GARDASIL": 0.3128786827781382, "HUMIRA": 2.742845064147514, "JAKAVI": 0.5158813246787133, "LEVOFLOXACIN": 0.3521715091305078, "METHOTREXATE": 0.4368186921136461, "MODERNA": 0.5450555261484794, "MYCOPHENOLATE": 1.8339118508976573, "OMALIZUMAB": 0.7483415031821389, "ORENCIA": 12.152543009605704, "PANTOPRAZOLE": 1.0542018772517174, "PEGASYS": 0.2085554903048643, "RITUXIMAB": 2.1188839004796804, "ROACTEMRA": 1.774053930583339, "SHINGRIX": 0.3803871062471559, "SIMPONI": 0.4339891733318443, "SPIKEVAX": 0.4020533107199358, "SUTENT": 0.0860466206976448, "TOZINAMERAN": 0.4850008633713962, "VAXZEVRIA": 0.4575622930395844, "XELJANZ": 0.994248895173108, "XOLAIR": 0.3082473432193877, "ZOSTAVAX": 1.372160880390344, "null": 0.1505415051113033}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2067.json
index c4b09243447..dd1295e462b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2067.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2067.json
@@ -1 +1 @@
-{"OPTIMARK": 2286.1969330859497}
\ No newline at end of file
+{"ARAVA": 6.592230742473302, "ROACTEMRA": 45.54848835879347, "null": 0.6687643384520832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2068.json
index 46849ce1206..f07a0f21c9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2068.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2068.json
@@ -1 +1 @@
-{"null": 5.8427672306832825}
\ No newline at end of file
+{"SUTENT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2069.json
index f771f620527..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2069.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2069.json
@@ -1 +1 @@
-{"null": 2.182707492679382}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/207.json
index 6da6e667bec..dc037a75264 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/207.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"MABTHERA": 79.25371624289451, "RITUXIMAB": 16.780053313370097, "null": 0.4831480980651569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2070.json
index d7bf2947791..a28515d2cd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2070.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2070.json
@@ -1 +1 @@
-{"ABATACEPT": 5.2053575294082295, "ACETAMINOPHEN": 13.452909459905571, "ACTOS": 1.317183898783849, "ADALIMUMAB": 4.250777413430337, "ADVATE": 6.771531811078156, "AIMOVIG": 1.9540023607902175, "ALEMTUZUMAB": 1.2258441578973631, "ALISKIREN": 6.2339418931359285, "AMINOSALICYLIC": 2.118331954108597, "ANAKINRA": 1.2397634166942648, "APREMILAST": 1.0382367372211327, "APREPITANT": 17.2122099043093, "ARAVA": 3.29227130298331, "AZILECT": 1.6932787352881666, "BELIMUMAB": 1.622684542534421, "BENLYSTA": 1.067199760829853, "BRILIQUE": 7.249762545711899, "BRINTELLIX": 2.0100393669967267, "BRUKINSA": 9.074132003070314, "CHLORHEXIDINE": 6.856317590891874, "CIMZIA": 3.856073233314604, "CINRYZE": 1.957989733228878, "CLOPIDOGREL": 2.465483121837764, "COLLAGENASE": 32.22100194002236, "COSENTYX": 1.4902053959701893, "COVID19": 2.257302088104975, "EFIENT": 2.8768384125875177, "ELIQUIS": 4.314768878041203, "ENOXAPARIN": 1.3559309893849696, "ENTECAVIR": 1.4998262359039731, "ERELZI": 2.4240079212811807, "EVISTA": 1.559299196922976, "FAMPYRA": 1.1448390023056472, "GARDASIL": 1.1589752484798987, "HEMLIBRA": 5.318568596240191, "HUMIRA": 1.0015160091609037, "IBRANCE": 1.151591224939522, "IMBRUVICA": 4.028294973911446, "INHIXA": 2.633901748787585, "IVABRADINE": 12.236948448083806, "JAKAVI": 1.0303665123011778, "KOVALTRY": 7.802982581547032, "LEMTRADA": 2.273657855535961, "LIXIANA": 2.60595841247187, "MAYZENT": 12.902804217982728, "MEMANTINE": 1.2964597334842227, "METHOTREXATE": 2.433857040288677, "NPLATE": 4.031802295293554, "OMALIZUMAB": 1.725818307670342, "PANTOPRAZOLE": 1.851038906799529, "PLAVIX": 4.908728369407085, "PLEGRIDY": 1.1858435724583842, "PRADAXA": 2.201419407419697, "PRASUGREL": 3.237816455384399, "RITUXIMAB": 1.0234328095235408, "RUCONEST": 1.5127320949494707, "SOMATROPIN": 3.217902387412193, "TEDUGLUTIDE": 4.422667764151881, "TICAGRELOR": 1.814919985739668, "TOZINAMERAN": 1.2477501964502755, "VAXZEVRIA": 1.5357662098865743, "XARELTO": 2.970303125603756, "XELJANZ": 1.1424467129910296}
\ No newline at end of file
+{"ARAVA": 0.8743969387394218, "BENLYSTA": 28.126996441217948, "BUDESONIDE": 17.709138302833093, "CIMZIA": 4.213206068264923, "COMIRNATY": 0.3801731091113661, "ENBREL": 5.182006794659711, "KAFTRIO": 25.451351606454637, "TOZINAMERAN": 0.661333027177338, "VAXZEVRIA": 0.2594027075979407, "null": 0.799371802110845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2071.json
index aae74a0243f..961e09dafd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2071.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2071.json
@@ -1 +1 @@
-{"null": 1.1754565013842662}
\ No newline at end of file
+{"null": 1.141705649344067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2072.json
index 1a8efa548d2..da3f41c9f0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2072.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2072.json
@@ -1 +1 @@
-{"CHAMPIX": 5.196758584192865, "CYMBALTA": 3.0508665641081056, "FENTANYL": 5.340141580600066, "GARDASIL": 21.537297112312565, "TAMIFLU": 6.234781747084353, "TOZINAMERAN": 1.9814336787648372, "null": 1.1154804537253489}
\ No newline at end of file
+{"ABATACEPT": 17.56228449331537, "ADALIMUMAB": 107.4405854327988, "APREMILAST": 58.05933439558506, "ARAVA": 11.95018163133427, "COSENTYX": 4.418592796998129, "MYCOPHENOLATE": 7.7084372572895585, "SPIKEVAX": 0.1564829235504793, "null": 0.0312401616744433}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2073.json
index 1521e380307..e6f1261f217 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2073.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2073.json
@@ -1 +1 @@
-{"null": 1.768819331899959}
\ No newline at end of file
+{"ABATACEPT": 29.577755591447133, "ADALIMUMAB": 48.15253189257161, "AIMOVIG": 3.5456178278884525, "AMINOSALICYLIC": 7.442237717755549, "ANAKINRA": 29.92601292052493, "APIXABAN": 0.9708019841346268, "APREMILAST": 21.789986044552595, "APREPITANT": 8.214585091180096, "ARAVA": 19.300813727227176, "AZATHIOPRINE": 6.862553493140989, "CELECOXIB": 3.04590867013248, "CERTOLIZUMAB": 28.349040487497543, "CICLOSPORIN": 1.6314356839612718, "CIMZIA": 4.372444007424441, "COMIRNATY": 0.0165570372419408, "COSENTYX": 3.943446657013221, "ENBREL": 21.495197759273097, "ENTYVIO": 1.063208800786332, "ERELZI": 10.15059560051462, "HUMIRA": 2.006925372147578, "IRBESARTAN": 1.949336340402484, "KEYTRUDA": 0.4057832295658533, "LEVOFLOXACIN": 0.333374369369887, "MYCOPHENOLATE": 3.4257231173121463, "RINVOQ": 0.9248552989542352, "RITUXIMAB": 1.4303200633661328, "null": 0.0314608206557605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2074.json
index 782b16e5fe1..e8324892e4d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2074.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2074.json
@@ -1 +1 @@
-{"null": 5.902802252869302}
\ No newline at end of file
+{"ARAVA": 2.989873492007707, "CIMZIA": 6.777750347482879, "DASATINIB": 134.67193232387604, "ENBREL": 33.206599961683715, "HUMIRA": 33.98570402831981, "KYMRIAH": 31.558231966858525, "ROACTEMRA": 20.93123357726968, "XELJANZ": 3.9372915336234926, "null": 0.1887136752892783}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2075.json
index eda6cc39b33..06050957946 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2075.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2075.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 28.39325056500068, "KEPPRA": 32.52956984647942, "null": 1.8003606734761728}
\ No newline at end of file
+{"ABACAVIR": 0.7462069244922297, "ABATACEPT": 10.921975440780797, "ABILIFY": 0.2413644121937378, "ACLASTA": 4.508806645776192, "ACTRAPID": 1.208380028173876, "ADALIMUMAB": 12.52562041887948, "ADENURIC": 1.7161571375928035, "AFINITOR": 1.4627104260833157, "AIMOVIG": 1.410361872472559, "ALEMTUZUMAB": 0.4171870936448477, "ALIMTA": 2.333829419537141, "AMIKACIN": 1.6610265763229723, "AMINOSALICYLIC": 0.647298462980459, "ANAKINRA": 11.41785541153523, "APIXABAN": 0.4129774925177731, "APREMILAST": 13.370135687516507, "ARANESP": 0.7447229689824219, "ARAVA": 3.05632849431567, "ARIPIPRAZOLE": 2.3444009485669914, "ASPARAGINASE": 1.149017185432782, "AUBAGIO": 0.2699745849802534, "AVANDIA": 0.1102481654292123, "AVASTIN": 0.860730450656384, "AXITINIB": 1.294923255330047, "AZACITIDINE": 0.919115947787015, "AZATHIOPRINE": 2.3071533649363314, "BAVENCIO": 3.689249932575298, "BENLYSTA": 0.3253195967082153, "BEVACIZUMAB": 0.4318982270933365, "BONVIVA": 0.6442546634935619, "BORTEZOMIB": 1.070989517893541, "BRAFTOVI": 1.400274001777547, "BUDESONIDE": 0.7358403413023852, "BUSULFAN": 0.8846337776229677, "CABOMETYX": 0.582815679522334, "CANCIDAS": 4.135054817194091, "CASPOFUNGIN": 0.904862312328094, "CELECOXIB": 8.540027514261237, "CELLCEPT": 1.7647855885608197, "CERTOLIZUMAB": 15.29486526640891, "CHAMPIX": 0.1614281043929804, "CICLOSPORIN": 2.8532572523105637, "CIMZIA": 1.198073654735411, "CLOPIDOGREL": 0.7222876966548585, "COAPROVEL": 0.6087413431466584, "COMIRNATY": 0.4297768264984495, "COMTAN": 3.2063918358434558, "COSENTYX": 4.868557121930645, "COTELLIC": 1.4444845750734423, "CUBICIN": 2.999257276831506, "CYMBALTA": 0.2960100893072389, "CYTARABINE": 1.5161680850544457, "DABRAFENIB": 2.9745741184208128, "DAPTOMYCIN": 2.576513694743252, "DARZALEX": 0.4968514586583309, "DEXAMETHASONE": 1.080336327731661, "DOCETAXEL": 1.0516535464660202, "DOXORUBICIN": 0.9776330221200394, "EBIXA": 2.0664902694829395, "ELIQUIS": 0.1695017650347073, "EMEND": 1.5724148458181813, "EMPAGLIFLOZIN": 1.2891957402697738, "ENBREL": 5.594122253263659, "ENTRESTO": 1.434706731134706, "ENTYVIO": 2.0432495732709643, "EPCORITAMAB": 11.71254140234428, "EPIVIR": 0.7706013796246473, "ERELZI": 9.422239932639645, "EXFORGE": 0.979281830188114, "EXJADE": 0.9915520679253258, "FASENRA": 0.6770059513184519, "FENTANYL": 0.737073843671651, "FILGRASTIM": 0.8589001760673787, "FORSTEO": 0.2843437486037883, "FORXIGA": 0.5222095747345433, "FULVESTRANT": 0.8758325121219116, "GALVUS": 0.9920426057912156, "GARDASIL": 0.3098148880045543, "GAZYVARO": 1.3443225518878985, "GLIVEC": 1.177139315266524, "HALAVEN": 0.9438343415878416, "HERCEPTIN": 0.7569763596417798, "HUMIRA": 2.7669065895181872, "HYCAMTIN": 1.972557512664391, "HYDROCORTISONE": 1.1557583164964689, "IBRANCE": 0.3490763329966068, "IBUPROFEN": 0.7234518055484122, "ICLUSIG": 1.4426868344330874, "INFLIXIMAB": 2.863773975197051, "INLYTA": 0.4487007210527887, "IPILIMUMAB": 0.6906886424237967, "IRINOTECAN": 1.158273565430024, "ISCOVER": 3.014901573046446, 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2.1787978560301577, "SOLIRIS": 0.8935457439943758, "SPIKEVAX": 0.2102524636272486, "SPINRAZA": 0.8966042415296046, "STALEVO": 0.8231034561004268, "STELARA": 1.284540384649562, "STIVARGA": 2.944054792195961, "SUTENT": 0.527250785670533, "SYNAGIS": 0.6566723606806999, "TAMIFLU": 0.6226678905748768, "TASIGNA": 0.6901241024315762, "TEMODAL": 1.6106722340538897, "TOCILIZUMAB": 2.434265704528589, "TORISEL": 2.218480462493136, "TOZINAMERAN": 0.3837905383023048, "TRACLEER": 0.5858932117892647, "TWINRIX": 1.018296643328713, "VAXZEVRIA": 0.1297467076672177, "VENCLYXTO": 2.2423657369786785, "VENETOCLAX": 1.7750030699161543, "VFEND": 0.93338214165114, "VORICONAZOLE": 1.9324346320367445, "VOTRIENT": 0.258677373671969, "XALKORI": 0.716817876590458, "XELJANZ": 3.058166996551458, "XELODA": 0.7259100991389081, "XOFIGO": 1.026552495890052, "XOLAIR": 0.838219186433459, "YESCARTA": 1.327576610475168, "ZELBORAF": 1.0132916912128531, "ZOSTAVAX": 0.2078449214477042, "ZYPADHERA": 1.1871562827161817, "ZYPREXA": 0.7887420819717192, "null": 0.795763692009637}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2076.json
index 6653bad59b1..1fa62ca5f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2076.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2076.json
@@ -1 +1 @@
-{"HUMAN": 99.2069815265432, "PRIVIGEN": 210.28683316964447, "SOLIRIS": 13.336696194738334, "null": 2.1019569977481214}
\ No newline at end of file
+{"EVENITY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2077.json
index 5c4b6e0bd41..54ed73afa8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2077.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2077.json
@@ -1 +1 @@
-{"DARZALEX": 586.978795038228}
\ No newline at end of file
+{"FORSTEO": 194.19005441068973}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2078.json
index 04ed1ef9a5b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2078.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2078.json
@@ -1 +1 @@
-{"null": 1.4934663403206134}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2079.json
index 59427499211..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2079.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2079.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 76.26573182148286, "BUSULFAN": 22.04517632426809, "CICLOSPORIN": 25.76180970303147, "PEGINTRON": 11.21888842208301, "null": 1.1816267779384932}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/208.json
index 311a3e8eec5..557aedfcb7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/208.json
@@ -1 +1 @@
-{"COMIRNATY": 9.27841672303305, "SPIKEVAX": 1.0913437535692638, "VAXZEVRIA": 6.205664932106696}
\ No newline at end of file
+{"SUBOXONE": 29.49043047496476, "TRUVADA": 27.41597793612541, "null": 0.6305172096516187}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2080.json
index a0812da5df0..a35b6a99c3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2080.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2080.json
@@ -1 +1 @@
-{"SOLIRIS": 36.323655983216646, "null": 1.3906157327811142}
\ No newline at end of file
+{"SOLIRIS": 223.61260198953107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2081.json
index 0856462c9ef..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2081.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2081.json
@@ -1 +1 @@
-{"ABILIFY": 1.419676879141073, "ALISKIREN": 108.41998079298318, "ANAKINRA": 2.3930557784256137, "ARIPIPRAZOLE": 2.8786317940678807, "AUBAGIO": 1.7564305527275923, "BUPIVACAINE": 2.0789379737135074, "CHAMPIX": 3.986987174558451, "CYMBALTA": 2.0035134503138297, "FAMPYRA": 1.4246316381898825, "GARDASIL": 1.4517614744821865, "IRBESARTAN": 2.2069641789403747, "KALETRA": 1.5051287068553645, "KEPPRA": 3.722329249092194, "LATUDA": 1.1825413762293329, "LEMTRADA": 1.3267468955388877, "LEVETIRACETAM": 3.885656072407611, "LEVOFLOXACIN": 1.265749098560818, "LYRICA": 1.7672496141100291, "MELATONIN": 3.960724421100133, "MIDAZOLAM": 1.939223456585139, "OLANZAPINE": 1.3571126953200718, "STALEVO": 2.886576406507133, "TAMIFLU": 1.435125208069091, "TWINRIX": 3.5286366255105928, "VIMPAT": 6.827824129920297, "ZYPADHERA": 5.333590560366172, "null": 1.9967090160213985}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2082.json
index 5c54809b054..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2082.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2082.json
@@ -1 +1 @@
-{"null": 2.59950973928883}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2083.json
index 035192e3b7e..e19ee8a31c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2083.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2083.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 11.711072825290394, "AVANDIA": 24.225855822519204, "BEDAQUILINE": 114.79615156336146, "OPSUMIT": 8.722431909006533, "REVATIO": 31.9503028950882, "TRACLEER": 75.32183481054007}
\ No newline at end of file
+{"POSACONAZOLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2084.json
index d21d25573f9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2084.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2084.json
@@ -1 +1 @@
-{"null": 3.018048574023795}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2085.json
index c4de1c150b1..ab9942bdc32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2085.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2085.json
@@ -1 +1 @@
-{"null": 2.23656444563837}
\ No newline at end of file
+{"YESCARTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2086.json
index 80a93b5173e..37205bf0439 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2086.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2086.json
@@ -1 +1 @@
-{"EYLEA": 79.22424473327833, "ZOSTAVAX": 12.484862253777656, "null": 2.1927608750352383}
\ No newline at end of file
+{"KYMRIAH": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2087.json
index 542a48bbfba..3ab6b41bd9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2087.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2087.json
@@ -1 +1 @@
-{"null": 1.915970905279455}
\ No newline at end of file
+{"CLADRIBINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2088.json
index fbe007726b9..d35bfdc6812 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2088.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2088.json
@@ -1 +1 @@
-{"null": 2.3242317539059485}
\ No newline at end of file
+{"FILGRASTIM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2089.json
index f63c763f251..7cfd381e690 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2089.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2089.json
@@ -1 +1 @@
-{"EYLEA": 17.64320088758087, "null": 6.317827000882044}
\ No newline at end of file
+{"NEVIRAPINE": 2550.2278007409845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/209.json
index d913bfd6a83..661fec5b2be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/209.json
@@ -1 +1 @@
-{"COMIRNATY": 10.807532311765884, "HIZENTRA": 1.7561069590395575, "NIMENRIX": 1.2193986651722204, "SPIKEVAX": 1.0908330605757937, "VAXZEVRIA": 6.621046934471762}
\ No newline at end of file
+{"KEYTRUDA": 5.9858941016063465, "NEXAVAR": 10.778957736920356, "null": 0.865507184625243}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2090.json
index 26946776f91..c7b9f836cfe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2090.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2090.json
@@ -1 +1 @@
-{"BEOVU": 29.88471962685086, "DEXAMETHASONE": 8.739561011373798, "ELIQUIS": 1.1551488356289723, "EYLEA": 27.68423639252491, "JETREA": 102.31673199909172, "LANTUS": 2.036670665358729, "NEVANAC": 192.1726580425674, "PEGASYS": 1.1244706611903883, "null": 2.705621617436817}
\ No newline at end of file
+{"ABACAVIR": 25.96849687412544, "ATRIPLA": 14.302981984996524}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2091.json
index ce30ad4470b..f50f088938f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2091.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2091.json
@@ -1 +1 @@
-{"ZOSTAVAX": 18.032862491740755, "null": 1.313055430152115}
\ No newline at end of file
+{"ABACAVIR": 16.693340216124966, "ATAZANAVIR": 11.570625021445732, "ATRIPLA": 2.9977831276002926, "BIKTARVY": 124.22977397105107, "CICLOSPORIN": 3.135400598905896, "COMBIVIR": 40.86046940252768, "COMIRNATY": 0.0687798825408902, "DARUNAVIR": 52.79424608060109, "EMTRICITABINE": 24.19391661546745, "GENVOYA": 119.993372288535, "ISENTRESS": 25.97944322430919, "KALETRA": 37.351141508248496, "LAMIVUDINE": 43.354955896552994, "LEMTRADA": 16.79773245758836, "NEVIRAPINE": 60.09547117088065, "PEGASYS": 1.3526088069972082, "PEGINTRON": 4.0338954823160815, "STRIBILD": 7.833713108836502, "TRUVADA": 2.5722120246246014, "VIREAD": 10.5701402684543, "null": 0.1366100498459939}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2092.json
index 22514f5ccc8..944791fae61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2092.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2092.json
@@ -1 +1 @@
-{"null": 1.070559733320756}
\ No newline at end of file
+{"LAMIVUDINE": 261.3801588479279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2093.json
index dea1fc36dde..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2093.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2093.json
@@ -1 +1 @@
-{"EYLEA": 29.88706782430245, "NEPAFENAC": 3128.8831920553766, "NEVANAC": 369.58054074730455, "null": 3.0279207656230938}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2094.json
index 218bbda3596..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2094.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2094.json
@@ -1 +1 @@
-{"null": 2.9451976209850206}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2095.json
index 692c9d0a7ef..a96a50dd56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2095.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2095.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.068910953729286, "TOZINAMERAN": 3.267039356919863, "VAXZEVRIA": 1.8465966941318812}
\ No newline at end of file
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2096.json
index 3a950c83a13..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2096.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2096.json
@@ -1 +1 @@
-{"null": 1.162750327229765}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2097.json
index c6ca0be683f..b4b7f82c10f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2097.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2097.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 17.68565594347568, "NEVANAC": 407.96652397015856, "null": 2.508694369401621}
\ No newline at end of file
+{"MEPOLIZUMAB": 2171.3791410812864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2098.json
index aae74a0243f..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2098.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2098.json
@@ -1 +1 @@
-{"null": 1.1754565013842662}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2099.json
index fa95c4fd233..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2099.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2099.json
@@ -1 +1 @@
-{"null": 1.6969029404075209}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/21.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/21.json
index 27feaa0e0cd..dc73984e7f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/21.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/21.json
@@ -1 +1 @@
-{"COVID19": 1.004447751203282, "DOCETAXEL": 5.028909578183704, "FORSTEO": 3.7720066505416714, "JANUVIA": 4.007638307492361, "ROTATEQ": 9.674878005715062, "null": 1.4428778089159888}
\ No newline at end of file
+{"AVASTIN": 9.114955028457958, "BEVACIZUMAB": 6.02159727780756, "BORTEZOMIB": 39.64266638877553, "CIMZIA": 5.403095107001551, "COMIRNATY": 0.0528267186266279, "DEXAMETHASONE": 4.124563114499276, "ENTYVIO": 11.879607178068024, "HUMIRA": 4.031100590227662, "JANUMET": 6.532095578303995, "JANUVIA": 5.411829508548316, "KEYTRUDA": 1.263464526468067, "LANTUS": 1.603807662359141, "NEXAVAR": 3.4208625086148183, "REMICADE": 18.45552283424037, "ROACTEMRA": 9.800777945523771, "SIMPONI": 2.708885514326054, "STELARA": 5.681127129346161, "STIVARGA": 4.218059667625735, "SUTENT": 2.3391581175465386, "null": 0.70327990752117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/210.json
index 4871e352faa..20c7ab7eaed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/210.json
@@ -1 +1 @@
-{"COMIRNATY": 3.734276723501122}
\ No newline at end of file
+{"ABACAVIR": 0.3004306287367806, "ABASAGLAR": 0.213048732099084, "ABILIFY": 0.337625747902799, "ABIRATERONE": 7.839449914233081, "ABRAXANE": 0.6263651219913215, "ACE": 2.5930696006450025, "ACLASTA": 2.92553289480419, "ACTOS": 2.1916074259147784, "ACTRAPID": 0.6567039565167392, "ADALIMUMAB": 0.011547330565044, "ADCIRCA": 0.6488902796840261, "ADEMPAS": 0.6872042010440101, "ADENURIC": 10.81439547236485, "ADVAGRAF": 4.952206932327359, "AERIUS": 0.5240549692059279, "AFINITOR": 0.9552816101737974, "AIMOVIG": 0.0902095794428076, "ALEMTUZUMAB": 1.2454669184588003, "ALIMTA": 3.555821019126201, "ALISKIREN": 1.2730732493172892, "AMIKACIN": 4.214671752057169, "AMINOSALICYLIC": 0.9189286310038636, "ANAKINRA": 0.1012208311597711, "ANGIOTENSIN": 9.00567855366251, "ANIDULAFUNGIN": 3.6412271830490575, "ANTIBIOTICS": 1.8734319138832876, "ANTINFLAMATORIOS": 62.45208257491737, "APIDRA": 0.2460973130047832, "APIXABAN": 0.4984832657076081, "APREMILAST": 0.3089337202120336, "APREPITANT": 0.3219390240190154, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2100.json
index 06218361e33..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2100.json
@@ -1 +1 @@
-{"null": 1.4880491677565826}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2101.json
index fd2002146d9..b4cfc19a412 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2101.json
@@ -1 +1 @@
-{"AZOPT": 96.09666368828076, "BEOVU": 45.77809101844687, "BIMATOPROST": 572.2240041111621, "DEXAMETHASONE": 6.267210427992417, "EYLEA": 86.31563507370522, "LEVOFLOXACIN": 4.428008563993886, "NEVANAC": 248.803231333354, "ZOSTAVAX": 1.8549987321218804, "null": 3.5397183472182707}
\ No newline at end of file
+{"null": 0.7497553903713977}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2102.json
index ebb0c1de26e..106c36c0d0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2102.json
@@ -1 +1 @@
-{"COMBIVIR": 15.354564899313944, "EYLEA": 22.833123397192978, "LUMIGAN": 533.1505615899403, "NAGLAZYME": 123.44992596131256, "NEVANAC": 236.5319627352152, "TOBRAMYCIN": 50.27483862616008, "ZOSTAVAX": 6.069480620509656, "null": 2.7483156997789377}
\ No newline at end of file
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0.5740420662081802, "RIXATHON": 0.4382342403454827, "ROACTEMRA": 0.5082847208368659, "ROTATEQ": 0.0374597844273365, "RUBRACA": 0.2033907642523129, "RUCONEST": 1.7164396871426442, "RUXOLITINIB": 0.349216359102886, "RYBELSUS": 0.1374602945101908, "SAXENDA": 0.1290011438452255, "SHINGRIX": 0.1250561864695864, "SILDENAFIL": 0.0575572007834625, "SIMPONI": 0.4393694221609809, "SKYRIZI": 1.857051520482676, "SOLIRIS": 0.2098084620812897, "SOMATROPIN": 0.5327050815421901, "SPIKEVAX": 1.469634966140577, "SPINRAZA": 0.5935561268156131, "SPRYCEL": 0.0981001714323618, "STELARA": 0.5368779752030893, "SUBOXONE": 0.0247429967274778, "SUTENT": 0.1055232692776302, "SYNAGIS": 1.06212356758149, "TACROLIMUS": 0.1110545835721234, "TAGRISSO": 0.2028027578074162, "TASIGNA": 0.0396830005087667, "TERIFLUNOMIDE": 0.7108113326709466, "TOCILIZUMAB": 0.6352124675507699, "TOUJEO": 0.1931152974989426, "TOVIAZ": 0.1335845854758569, "TOZINAMERAN": 4.37874169778368, "TRELEGY": 1.017217077124304, "TREMFYA": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2103.json
index b2e7b6bb632..018ed66ffd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2103.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"CIMZIA": 1.116016725973232, "COMIRNATY": 4.653221381634977, "EVENITY": 0.762335552707844, "HUMAN": 0.6634453194980197, "HUMIRA": 0.14034859664425, "JANSSEN": 30.132228411880945, "JCOVDEN": 11.913113570655238, "KEPPRA": 0.0605490061840598, "MODERNA": 11.405679586884942, "SPIKEVAX": 16.61900265116591, "TOZINAMERAN": 0.0109915505363273, "VAXZEVRIA": 0.1587355201510171, "null": 0.0059631181733931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2104.json
index 1cb3ba02474..b054463ec8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2104.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 13.440651301634317, "LEVOFLOXACIN": 15.140872343756246, "NEVANAC": 284.4957059669732, "VORICONAZOLE": 45.04785603545755, "null": 1.8463669081445224}
\ No newline at end of file
+{"ACTRAPID": 10.448021533724388, "ADVAGRAF": 17.882342427739424, "ANIDULAFUNGIN": 38.77825477129275, "APIXABAN": 0.5927153553903012, "AUBAGIO": 0.981729298826992, "AZACITIDINE": 5.022562084400602, "CARFILZOMIB": 6.440536399999098, "CELLCEPT": 5.812902923802018, "CIMZIA": 0.2442957427873729, "CLOPIDOGREL": 0.4998991177090809, "COMIRNATY": 2.0188700671665387, "CYMBALTA": 0.2479266577176536, "CYTARABINE": 1.6705370152765244, "DARZALEX": 2.265119647307373, "DEXAMETHASONE": 4.706866553598397, "DOXORUBICIN": 2.4565337170204247, "ELIQUIS": 2.325837574499511, "EPCORITAMAB": 49.54761825988718, "EVUSHELD": 37.67549896918361, "FASENRA": 2.714886671345794, "FIRDAPSE": 2.835437323855892, "FORXIGA": 0.8835341502309256, "HUMIRA": 0.7832642489190381, "IBRANCE": 0.8488948843515983, "JAKAVI": 2.0295579820418705, "JARDIANCE": 2.6284649607206942, "KALETRA": 1.8846315290299571, "KEYTRUDA": 0.3788962493026095, "LANTUS": 0.2282854465104831, "LEVEMIR": 1.217856702635114, "LEVOFLOXACIN": 0.6803779078046489, "LOPINAVIR": 7.5465038571801, "MEPOLIZUMAB": 1.54042437602791, "METHOTREXATE": 1.1456424831587693, "MODERNA": 3.190515885320516, "MYCOPHENOLATE": 4.37840932876692, "OBINUTUZUMAB": 35.547773488051604, "OFEV": 2.2884836677368563, "OPDIVO": 0.9446096945506296, "OPSUMIT": 0.6651681163513921, "REMDESIVIR": 34.24699511137553, "RINVOQ": 1.344802640156239, "RITUXIMAB": 8.63966181408633, "RIXATHON": 9.656751711134955, "ROACTEMRA": 1.0158743024745067, "SIMPONI": 1.120131690155072, "SOLIRIS": 1.64845701457506, "SPIKEVAX": 2.255932866562324, "SPINRAZA": 3.458310336004075, "STELARA": 0.7939189072602005, "TOCILIZUMAB": 7.925769766432829, "TOZINAMERAN": 2.029077325726268, "TRELEGY": 3.8394041521537647, "TREMFYA": 3.300589145769273, "VAXZEVRIA": 0.9120468891806848, "VEKLURY": 79.24514042561715, "VENCLYXTO": 10.228899579625168, "XELJANZ": 1.8244683170947755, "null": 0.2566824709405064}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2105.json
index 8e8c80e45b6..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2105.json
@@ -1 +1 @@
-{"null": 2.1706108345009483}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2106.json
index 375e6fdb467..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2106.json
@@ -1 +1 @@
-{"COMTAN": 163.64007628756076, "TOZINAMERAN": 2.372906676943211, "null": 1.1350607207379937}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2107.json
index d236dc837a0..6492189524a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2107.json
@@ -1 +1 @@
-{"ZOSTAVAX": 44.56044824106241, "null": 1.409461477736308}
\ No newline at end of file
+{"KALETRA": 465.5448005527561, "VEKLURY": 1777.5010644299607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2108.json
index 7328a2e7554..54571e6351e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2108.json
@@ -1 +1 @@
-{"null": 1.690422363166397}
\ No newline at end of file
+{"null": 1.3567313752047652}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2109.json
index 4148cfb31a9..dc924b70337 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2109.json
@@ -1 +1 @@
-{"NEVANAC": 883.7926876336411, "null": 1.3983983824666226}
\ No newline at end of file
+{"ABACAVIR": 21.08616618887081, "ATAZANAVIR": 2393.356414907418, "EMTRICITABINE": 299.2731372212314, "LAMIVUDINE": 130.4136955617939}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/211.json
index 23b055efad1..1e50b341496 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/211.json
@@ -1 +1 @@
-{"null": 3.77657001277882}
\ No newline at end of file
+{"COMIRNATY": 0.1761847214269789, "ONGLYZA": 891.8311966297554, "SPIKEVAX": 0.9991433406449676, "ZOSTAVAX": 7.1992385345176455, "null": 0.7197059652845795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2110.json
index 263e53d5c4a..7509e82f234 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2110.json
@@ -1 +1 @@
-{"LANTUS": 10.779822262876351, "null": 1.4811837924724789}
\ No newline at end of file
+{"COMIRNATY": 1.429151153501293, "null": 0.8102443015074874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2111.json
index b06249d4c95..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2111.json
@@ -1 +1 @@
-{"AVANDIA": 22.041970804782157, "AZATHIOPRINE": 11.629214092381131, "JANUMET": 6.778043084729179, "null": 5.477499009509459}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2112.json
index 9970ee638e7..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2112.json
@@ -1 +1 @@
-{"AVANDAMET": 55.372997306132895, "AVANDIA": 44.21262373050259, "BYETTA": 12.428340299175249, "CLOPIDOGREL": 1.837129716736441, "ELIQUIS": 1.493973622339875, "HUMALOG": 1.3516482055823849, "JANUMET": 7.868938740092327, "JANUVIA": 7.073050111959407, "JARDIANCE": 2.735760936899989, "LANTUS": 2.897441379422162, "LEVEMIR": 6.089964122745548, "PLAVIX": 7.942217765510513, "RANOLAZINE": 55.06700379693664, "STELARA": 2.0227760323496184, "TRELEGY": 11.870127098536482, "ZOSTAVAX": 3.675918806280832, "null": 1.1005123332685331}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2113.json
index c300a4e66fe..1b1e859f6e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2113.json
@@ -1 +1 @@
-{"HUMAN": 125.62785344549354}
\ No newline at end of file
+{"FASENRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2114.json
index 17ed76aaa3b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2114.json
@@ -1 +1 @@
-{"ACLIDINIUM": 51.48872669795927, "APIDRA": 2.067180869317517, "AVANDAMET": 116.1391656005156, "AVANDIA": 118.96077847315031, "BYETTA": 5.515673891298287, "CLOPIDOGREL": 3.4960660241213137, "HUMALOG": 2.5464972087956617, "JANUMET": 4.457058950477769, "JANUVIA": 6.714038317963123, "JARDIANCE": 7.473150337126444, "LANTUS": 7.961946429772506, "LEVEMIR": 2.6046800893845363, "PANTOPRAZOLE": 7.934871352749409, "PLAVIX": 1.3517986925178778, "ROSIGLITAZONE": 47.88629246673455, "STELARA": 1.5807828518790443, "ZOSTAVAX": 1.682288998837639, "null": 1.118820356738159}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2115.json
index 0f8214e4aa8..7356d33a96c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2115.json
@@ -1 +1 @@
-{"ABACAVIR": 1.6706972561124047, "ACTOS": 7.206214271665215, "APROVEL": 1.4905286526644144, "ATAZANAVIR": 1.1769432105470672, "AVANDAMET": 169.08569785564652, "AVANDIA": 179.02602553093664, "BEDAQUILINE": 2.2083481095669883, "BOSULIF": 1.2759294912246784, "BRILIQUE": 1.478921144219272, "BUMETANIDE": 4.215655511604572, "BYDUREON": 1.846888182656004, "BYETTA": 4.830367515769646, "CHOLESTAGEL": 31.874893640405126, "CIALIS": 4.193942586660072, "CLOPIDOGREL": 3.9681945353950256, "CRIXIVAN": 2.0827210679519155, "EDOXABAN": 15.759061906866531, "ELIQUIS": 1.1489743463699644, "ENTRESTO": 1.0705826617916518, "EPIVIR": 2.7273975375667847, "EVENITY": 1.0160929749098755, "FEBUXOSTAT": 8.957164346603985, "GLYCOPYRRONIUM": 4.705417660094238, "HUMALOG": 2.65238476180101, "HYDROCORTISONE": 1.9214375556604275, "ICLUSIG": 6.018269049740005, "INSULIN": 1.345248256022152, "INTEGRILIN": 5.419246917653654, "IRBESARTAN": 1.3085861500392968, "JANUMET": 3.2301725551153213, "JANUVIA": 4.39884907423497, "LANTUS": 1.873738006371642, "LEVOFLOXACIN": 1.136790192613951, "MICARDIS": 1.0252631656702171, "NILOTINIB": 5.716901534865498, "NPLATE": 1.6029709981744555, "ONGLYZA": 21.52815461128047, "PLAVIX": 2.4728509277392035, "RANOLAZINE": 3.265290094761527, "RAPAMUNE": 1.7179979029349688, "ROSIGLITAZONE": 51.15801394968886, "SPIRONOLACTONE": 2.121879978125937, "SPRYCEL": 1.4446407101285157, "TASIGNA": 11.219695878800598, "TESTOSTERONE": 11.698049165440857, "TICAGRELOR": 1.6117558087514494, "VALSARTAN": 1.6041451239606566, "VIAGRA": 2.5426195759498254, "ZOSTAVAX": 3.702522649773601, "ZYPREXA": 1.4043711364682177}
\ No newline at end of file
+{"null": 1.0958409605194477}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2116.json
index 34a2570f3aa..a627c43aae9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2116.json
@@ -1 +1 @@
-{"ANGIOX": 1089.2542757072365, "CLOPIDOGREL": 10.746012386085818}
\ No newline at end of file
+{"null": 0.4100884269517391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2117.json
index 4c3d455099f..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2117.json
@@ -1 +1 @@
-{"null": 1.301127939412748}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2118.json
index f9d65b0a481..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2118.json
@@ -1 +1 @@
-{"null": 1.1494335205126125}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2119.json
index 6d859b49969..53018e3eb5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2119.json
@@ -1 +1 @@
-{"ANGIOX": 37.35231260250416, "APIDRA": 1.511165211483171, "AVANDAMET": 16.115326487772382, "AVANDIA": 16.685233151392737, "BENLYSTA": 1.421154286092055, "BRILIQUE": 4.728363378456091, "BYDUREON": 8.89586596694438, "BYETTA": 2.820992169543418, "CLOPIDOGREL": 5.421516357231493, "ELIQUIS": 1.3122256540752406, "FORXIGA": 4.484737493990828, "HUMALOG": 3.982714921896443, "HUMIRA": 2.1742283244188614, "ICLUSIG": 4.181051839897023, "INSULIN": 2.3730297095250528, "INTEGRILIN": 13.338233526765263, "JARDIANCE": 1.9083500264491196, "LANTUS": 3.2478223314001315, "LEVEMIR": 3.332643557418689, "MICARDIS": 1.962534461261358, "NORVIR": 4.184810950196142, "PLAVIX": 23.35166740383886, "RITUXIMAB": 1.9790848316110383, "STELARA": 1.0487372976673923, "TASIGNA": 10.821124267484125, "TESTOSTERONE": 6.878589948916703, "TICAGRELOR": 6.677786758875344, "TRELEGY": 1.2753297304799929, "TRULICITY": 1.3102522693273246, "VIAGRA": 3.917861189597612, "VICTOZA": 2.3532820597172592, "XELJANZ": 1.0429540236540435, "null": 1.8057697180937475}
\ No newline at end of file
+{"RIBAVIRIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/212.json
index bf4e302ba11..e4a01cab495 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/212.json
@@ -1 +1 @@
-{"COMIRNATY": 1.665509378034935, "SPIKEVAX": 2.031268287377796}
\ No newline at end of file
+{"CICLOSPORIN": 2.139587034053692, "COMIRNATY": 0.1794612861681658, "CYTARABINE": 7.054406070085901, "DEXAMETHASONE": 3.616592444754619, "EXJADE": 49.21185453598088, "JAKAVI": 31.327730510152374, "LYNPARZA": 15.199785051210522, "NPLATE": 11.176246968425763, "SOLIRIS": 5.94417906878282, "SPIKEVAX": 0.1378774187162944, "VAXZEVRIA": 0.0952987992127359, "VFEND": 6.87834777051642, "null": 1.0297434864306103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2120.json
index 75d9e957e09..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2120.json
@@ -1 +1 @@
-{"ANGIOX": 7196.372120109358}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2121.json
index 6547e6d67ff..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2121.json
@@ -1 +1 @@
-{"null": 1.1495562290499932}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2122.json
index fca4290fc3f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2122.json
@@ -1 +1 @@
-{"BRILIQUE": 43.64041067992903, "CLOPIDOGREL": 11.349834853441555, "EFIENT": 215.6312444510972, "PLAVIX": 33.19882751125416, "null": 1.238719520377268}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2123.json
index f8667568de5..71b793d5a90 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2123.json
@@ -1 +1 @@
-{"AVANDAMET": 8.483288827221196, "AVANDIA": 5.277059551346465, "BRILIQUE": 15.429244526010958, "BYETTA": 2.541753336513328, "CHAMPIX": 1.3337508861738645, "CICLOSPORIN": 1.5609409729307748, "CLOPIDOGREL": 8.224778238425733, "DULOXETINE": 8.301657296933135, "EFIENT": 38.20466029815059, "FORSTEO": 1.4502097891040662, "FORXIGA": 4.468416731824837, "ICLUSIG": 28.538648969253117, "INSULIN": 2.615328110325524, "JARDIANCE": 1.2087759116695178, "NEXAVAR": 2.170399361140439, "NILOTINIB": 41.54664126575262, "OLANZAPINE": 1.2495734195141086, "PLAVIX": 6.49371448584202, "STELARA": 1.2203912859250912, "TASIGNA": 15.07416756865447, "TICAGRELOR": 15.183550255424525, "VIAGRA": 2.757629495168243, "null": 1.1246208580407329}
\ No newline at end of file
+{"INLYTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2124.json
index 38d5b65b9c7..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2124.json
@@ -1 +1 @@
-{"ANGIOX": 731.2447008081293, "AVANDIA": 4.819469542878076, "BRILIQUE": 10.927726403589896, "CHAMPIX": 1.6685647855708452, "CLOPIDOGREL": 17.235388235048, "INTEGRILIN": 179.42443305229153, "PLAVIX": 13.131033253766349, "VAXZEVRIA": 1.0992138662243127, "ZYLLT": 160.65552500694767}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2125.json
index 81f5a824fd8..fc1bf5e6e78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2125.json
@@ -1 +1 @@
-{"NOVOSEVEN": 1849.405728704364}
\ No newline at end of file
+{"COMIRNATY": 0.6840542896119911, "DEXAMETHASONE": 62.1567549657021}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2126.json
index 6850942f5b6..6928bac8b7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2126.json
@@ -1 +1 @@
-{"AIMOVIG": 3.7059863908644046, "ALEMTUZUMAB": 6.08571060657496, "ASPARAGINASE": 19.581115861660333, "AUBAGIO": 2.1517227683798947, "AZATHIOPRINE": 3.654108917992733, "BENLYSTA": 8.80104592298463, "CICLOSPORIN": 1.3237139673653917, "CIMZIA": 1.4460281894385831, "COSENTYX": 6.081690773725959, "DESCOVY": 18.06784843576593, "DEXAMETHASONE": 1.5951504597653523, "ENTRESTO": 1.1613705258681148, "ENTYVIO": 2.351810579779401, "ENVARSUS": 170.60553019527586, "ESBRIET": 4.509321401296473, "FAMPYRA": 23.26906898061623, "JAKAVI": 7.737447925725832, "KALETRA": 3.782319001564674, "KESIMPTA": 38.14334658421333, "KEYTRUDA": 3.4957323234854005, "MEPOLIZUMAB": 5.158658257363304, "NUCALA": 7.874167899892764, "OFEV": 3.8549080581601096, "OPDIVO": 3.072776966096285, "PLEGRIDY": 13.071021852545682, "RINVOQ": 10.883178419716408, "ROACTEMRA": 1.9624825373892032, "SHINGRIX": 3.585258967277259, "SIMPONI": 5.761598915612019, "SYMTUZA": 52.27277024392599, "SYNAGIS": 9.377845584677708, "TRELEGY": 11.163662834070758, "VELTASSA": 9.024962822027758, "XELJANZ": 1.4708918285109571, "XOLAIR": 2.790707510922037}
\ No newline at end of file
+{"CICLOSPORIN": 9.155233019054338, "SPINRAZA": 767.8668887336981, "null": 0.645362930351063}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2127.json
index 0d35e9d81e0..375a85841c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2127.json
@@ -1 +1 @@
-{"COVID19": 37.84405664697479}
\ No newline at end of file
+{"CICLOSPORIN": 9.57311428642345, "COMIRNATY": 0.9744883833574888, "SPIKEVAX": 0.2687747487285374, "SPINRAZA": 130.96199138448975, "VAXZEVRIA": 0.1857730614556244, "null": 0.7916913414414465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2128.json
index 6988cfdbce7..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2128.json
@@ -1 +1 @@
-{"BENLYSTA": 25.31449839667781, "COSENTYX": 8.119223556548526, "LEVOFLOXACIN": 7.502933792716737, "MEPOLIZUMAB": 12.13701612054356, "NUCALA": 34.91366486644537, "TRELEGY": 30.455702664025164}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2129.json
index ca41f72414a..8b47c3733f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2129.json
@@ -1 +1 @@
-{"null": 35.92416861404185}
\ No newline at end of file
+{"NAGLAZYME": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/213.json
index 1e2ad41f088..03945c914f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/213.json
@@ -1 +1 @@
-{"SPIKEVAX": 2.7611885244173955, "null": 1.1329851728214306}
\ No newline at end of file
+{"LEFLUNOMIDE": 121.32072006077128, "RITUXIMAB": 41.41137940320655, "null": 1.3963124563726326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2130.json
index 6c10ec8b5f6..f7173480551 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2130.json
@@ -1 +1 @@
-{"LANTUS": 12.103450646998336, "null": 1.1232634885918429}
\ No newline at end of file
+{"CICLOSPORIN": 10.248148280233332, "COMIRNATY": 0.5213226334505169, "SPINRAZA": 61.07861641853554, "null": 1.4542500656815378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2131.json
index 22514f5ccc8..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2131.json
@@ -1 +1 @@
-{"null": 1.070559733320756}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2132.json
index ce3de9c83f2..269b0f63507 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2132.json
@@ -1 +1 @@
-{"KEYTRUDA": 22.80020933166875, "null": 1.000285861195658}
\ No newline at end of file
+{"CICLOSPORIN": 51.87407437230438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2133.json
index fb3897e303b..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2133.json
@@ -1 +1 @@
-{"ATAZANAVIR": 36.988856913248135, "BUDESONIDE": 11.5595213797682, "FLUTICASONE": 44.476034969897945, "HYDROCORTISONE": 27.446090241778634, "IPILIMUMAB": 7.824902358335052, "KALETRA": 11.619649308298085, "KEYTRUDA": 17.021529919785316, "LOPINAVIR": 63.88734121257639, "NORVIR": 34.022475760079764, "OPDIVO": 17.502826210074264, "PEMBROLIZUMAB": 11.87311502579998, "RELVAR": 15.227233177621487, "RITONAVIR": 88.51905521954818, "null": 1.7997033650237215}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2134.json
index e78bdce14f9..d8ff5fb4e76 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2134.json
@@ -1 +1 @@
-{"null": 1.4641793956652778}
\ No newline at end of file
+{"null": 0.607446179040787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2135.json
index bef4c4676c0..8b5194a1f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2135.json
@@ -1 +1 @@
-{"KEYTRUDA": 8.853931365442943, "null": 1.845060704250425}
\ No newline at end of file
+{"LEMTRADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2136.json
index 257ea33c275..16bb7d54cbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2136.json
@@ -1 +1 @@
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\ No newline at end of file
+{"null": 0.7889979766615597}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2137.json
index 314d08b4d2e..ead8725c17e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2137.json
@@ -1 +1 @@
-{"null": 2.059807064143012}
\ No newline at end of file
+{"null": 0.6805743670107615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2138.json
index 9e322084633..28121f4aaa0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2138.json
@@ -1 +1 @@
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\ No newline at end of file
+{"null": 4.139418728484751}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2139.json
index 2242295ec64..db7aae691de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2139.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6618091949378386}
\ No newline at end of file
+{"null": 1.358446126336236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/214.json
index fc6ce93aa93..c8ed4f6d32c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/214.json
@@ -1 +1 @@
-{"COMIRNATY": 4.840036543297722, "HIZENTRA": 19.77842550969847, "ROACTEMRA": 9.76559080280046, "SPIKEVAX": 1.064874780700734, "VAXZEVRIA": 2.631533826863067}
\ No newline at end of file
+{"ASPARAGINASE": 42.91349536039485, "BLINATUMOMAB": 114.48249294546738, "BLINCYTO": 93.27382365872154, "BORTEZOMIB": 28.993445463826863, "BUSILVEX": 57.448449464922845, "BUSULFAN": 10.01702996814508, "CICLOSPORIN": 2.969409308678652, "CLOFARABINE": 81.50811653228288, "COMIRNATY": 0.0832291566590642, "CYTARABINE": 23.18504132189374, "DASATINIB": 49.39375675496954, "DEXAMETHASONE": 6.211223301689223, "DOXORUBICIN": 6.604668079091947, "ICLUSIG": 69.15736258283168, "JAKAVI": 4.305886396688705, "KYMRIAH": 90.54376377264838, "METHOTREXATE": 4.342191857889745, "REVLIMID": 15.250772378051789, "STELARA": 1.2470671469287384, "TASIGNA": 7.4841078068340385, "THALIDOMIDE": 15.812596111587196, "THERAPEUTIC": 200.72756871358172, "VFEND": 6.079314770104907, "null": 0.6890218695669527}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2140.json
index 51b9b891a86..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2140.json
@@ -1 +1 @@
-{"FENTANYL": 24.72306468004015, "GLIBENCLAMIDE": 134.63686688493428, "JANUMET": 9.336665682361522, "VIAGRA": 20.12346273094249, "null": 1.1394022903645755}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2141.json
index 202cbad25d0..786eafa6d64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2141.json
@@ -1 +1 @@
-{"GARDASIL": 24.228647034438715}
\ No newline at end of file
+{"ABACAVIR": 5.432932494579837, "ADCIRCA": 14.178485024584898, "AFINITOR": 4.86249796828422, "AMIKACIN": 9.841647946733753, "ARAVA": 0.4038767598647562, "ATRIPLA": 0.216333877204467, "AVASTIN": 2.731118142576121, "BUPRENORPHINE": 2.582258049410827, "CAPECITABINE": 3.570524808244387, "CICLOSPORIN": 2.6529673846992425, "COMIRNATY": 0.1338192110199914, "CRIXIVAN": 9.831482652221489, "DACLATASVIR": 24.54439833452568, "DARUNAVIR": 12.872436828718955, "EFAVIRENZ": 8.084096005892905, "ELTROMBOPAG": 108.32253882961514, "FORSTEO": 1.5204203932793907, "JAKAVI": 4.096549312134162, "JANUVIA": 3.513754608801292, "JARDIANCE": 1.8666949400123911, "KALETRA": 14.551918308877196, "KEYTRUDA": 1.5667914723402854, "LAMIVUDINE": 7.106099736861508, "LANTUS": 0.6371020869134302, "LEVETIRACETAM": 4.305684461103573, "NEXAVAR": 4.799714315454355, "OLANZAPINE": 1.3099596947960703, "PEGASYS": 1.2282536615320652, "PEMBROLIZUMAB": 4.193280860097438, "SPIKEVAX": 0.0760695972063555, "STIVARGA": 3.156855688692747, "SUTENT": 2.438230656936253, "TRACLEER": 1.932800640216533, "XTANDI": 1.5609943275570912, "null": 0.8750495876037446}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2142.json
index 47c4424b3fe..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2142.json
@@ -1 +1 @@
-{"COMIRNATY": 3.80291233442616}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2143.json
index 5450711d0d0..fba47bad1ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2143.json
@@ -1 +1 @@
-{"TELMISARTAN": 95.0725410915532, "ZOSTAVAX": 5.87469429796592}
\ No newline at end of file
+{"ABILIFY": 9.976358880353578, "ARANESP": 0.9922385231457104, "ATAZANAVIR": 16.08058716161095, "BRIVIACT": 6.80543562182607, "CICLOSPORIN": 1.7911488478968276, "CIMZIA": 9.274755043025657, "CLOPIDOGREL": 0.8457887203098365, "COMBIVIR": 27.38231212110665, "COMIRNATY": 0.0443899302205115, "CYTARABINE": 2.094640100912001, "DARUNAVIR": 9.066056670700966, "EFAVIRENZ": 16.722194616648817, "ELIQUIS": 0.3107435636196549, "EMTRIVA": 26.86289957186088, "ENOXAPARIN": 5.477125133142721, "EPIVIR": 15.167831135866484, "FAMPYRA": 3.21063739457929, "FENTANYL": 6.346287222970596, "GARDASIL": 2.726917553068876, "HUMALOG": 0.8254205334707292, "HYDROCORTISONE": 4.6666713983625865, "IBUPROFEN": 1.903358365685368, "INSULIN": 3.2070804102115846, "ISENTRESS": 36.891396306511126, "JANUMET": 1.361786189715272, "JARDIANCE": 1.1591779234716166, "KALETRA": 8.449028465782801, "KEPPRA": 9.444928757228002, "LEVEMIR": 2.5722378764896843, "LEVETIRACETAM": 2.828039017847453, "MIDAZOLAM": 4.137306589951604, "MMRVAXPRO": 1.79771217498666, "NEVIRAPINE": 31.671640644760345, "NORVIR": 37.7469176081207, "OPSUMIT": 1.1427314299260851, "PLEGRIDY": 5.178243503157975, "REYATAZ": 59.272017959283446, "RUCONEST": 15.033093308490317, "SOLIRIS": 1.640887572835798, "SPIKEVAX": 0.0515715371950804, "STELARA": 2.009027957993999, "SUBOXONE": 1.4230062262554826, "TOUJEO": 6.202470264167431, "VIMPAT": 5.660992204909679, "XOLAIR": 0.9234699382691516, "null": 1.472350347162384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2144.json
index 0a006d5e135..d0391dc2610 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2144.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1423876050962378}
\ No newline at end of file
+{"ASPARAGINASE": 409.5982213616621, "null": 1.014706308781459}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2145.json
index 128bbf04922..654b810c7c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2145.json
@@ -1 +1 @@
-{"null": 1.6317463676500423}
\ No newline at end of file
+{"OMALIZUMAB": 348.7009279041925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2146.json
index 6b4bfc6ae1d..3c5ba3ad88f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2146.json
@@ -1 +1 @@
-{"AIMOVIG": 5.950020998808764, "BRILIQUE": 6.373055062800956, "ELIQUIS": 2.15538603184477, "ENTRESTO": 4.222639285865616, "GARDASIL": 1.6096696707974305, "HUMALOG": 1.83800673497187, "HYDROCORTISONE": 16.107018054627154, "KEPPRA": 5.531104310458717, "LANTUS": 2.578989249239867, "LYRICA": 4.4351455254234535, "SERTRALINE": 167.3458246406038, "SUBOXONE": 3.0883414613299, "ZOSTAVAX": 1.6977756568121851, "ZYPREXA": 2.2033645574720486, "null": 1.6031317501734172}
\ No newline at end of file
+{"IBRANCE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2147.json
index fc7d40f9779..9ac2e216d7a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2147.json
@@ -1 +1 @@
-{"null": 8.82757320125621}
\ No newline at end of file
+{"null": 0.925299144556582}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2148.json
index bb0f10b430d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2148.json
@@ -1 +1 @@
-{"null": 1.7106632264816388}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2149.json
index 17a02bde84b..4150b9b641f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2149.json
@@ -1 +1 @@
-{"ATRIPLA": 10.843770904310936, "CYMBALTA": 1.3638373302877684, "ELIQUIS": 2.3928531506801227, "FORSTEO": 2.0073446116279654, "GARDASIL": 1.927302442504138, "HUMALOG": 1.6276371058087211, "KEPPRA": 6.769142170063106, "MELATONIN": 28.912226248069658, "OPSUMIT": 1.7274856996091088, "STRIBILD": 5.086296515270692, "SUBOXONE": 7.370287345637366, "TRIUMEQ": 16.00323880016695, "TRUVADA": 5.097710488625307, "VIAGRA": 3.734543129463785, "XELJANZ": 1.4591298924734122}
\ No newline at end of file
+{"CICLOSPORIN": 92.08571746962068, "null": 0.5899625428937079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/215.json
index c710562903f..be013d5f0aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/215.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7965905137217797, "COVID19": 1.3430888354044934, "SPIKEVAX": 1.5117403688527755}
\ No newline at end of file
+{"ASPARAGINASE": 75.60729679708479, "BLINATUMOMAB": 535.6643440204251, "BLINCYTO": 595.8548514827819, "BUSILVEX": 56.284012797622, "CICLOSPORIN": 12.218235916316235, "CYTARABINE": 54.58684806722853, "DASATINIB": 199.56251423669676, "DEXAMETHASONE": 8.809030256787274, "ICLUSIG": 126.7784429543712, "KYMRIAH": 584.0499794171417, "MERCAPTOPURINE": 18.25062755230499, "NILOTINIB": 26.79481134470553, "SPRYCEL": 15.998468666897082, "TISAGENLECLEUCEL": 213.7602463923735, "null": 0.0604722384623174}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2150.json
index b1d36a273fb..e6898e061f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2150.json
@@ -1 +1 @@
-{"SOMATROPIN": 626.4802843396005, "null": 5.236119233706769}
\ No newline at end of file
+{"BELIMUMAB": 251.7007607167891, "BENLYSTA": 7.49986041760068, "COMIRNATY": 0.0704006187800487, "FORSTEO": 11.234325312645652, "HYDROCORTISONE": 23.9243125100032, "KEPPRA": 2.877423932822298, "null": 1.4579546699675074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2151.json
index 6c1939f7dbb..4b121e6bb6c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2151.json
@@ -1 +1 @@
-{"null": 15.750694915829232}
\ No newline at end of file
+{"ARANESP": 6.872483429105612, "CINACALCET": 300.190411977793, "FORSTEO": 3.964565335270956, "IRON": 98.92084155750275, "MIMPARA": 153.1362978240474, "TERIPARATIDE": 159.30080992833138, "null": 6.149536463947236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2152.json
index 80546888d4a..05bc5dad48a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2152.json
@@ -1 +1 @@
-{"ELIQUIS": 33.93874012961033, "KEPPRA": 11.254252410988618}
\ No newline at end of file
+{"ATRIPLA": 3.749111078947583, "AVAMYS": 21.52564672844944, "ENTYVIO": 20.181014780779343, "null": 1.9348431714629544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2153.json
index c8cb17e5f77..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2153.json
@@ -1 +1 @@
-{"ELIQUIS": 9.627683228623953, "JARDIANCE": 28.773943708448492}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2154.json
index e222f697c21..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2154.json
@@ -1 +1 @@
-{"ALIMTA": 10.038157603883564, "AMBROXOL": 394.00520379334097, "AMLODIPINE": 334.2392335047507, "BEDAQUILINE": 4.030159294361988, "BIKTARVY": 3.012603968842698, "CAFFEINE": 239.34372577795668, "CICLOSPORIN": 2.339904087999549, "CLOPIDOGREL": 1.735724257396308, "CUBICIN": 4.480271865471554, "ELIQUIS": 1.9496155808568625, "EMTRICITABINE": 10.426168998461415, "ENTECAVIR": 20.202244273293964, "ENTRESTO": 3.23681990328769, "EXJADE": 9.994502285767645, "FORXIGA": 2.1802354118979985, "HEPSERA": 21.44767353389637, "IBUPROFEN": 1.340795612899088, "JAKAVI": 2.864971886958477, "LEVOFLOXACIN": 119.66811580070424, "LYNPARZA": 2.839541595553669, "PANTOPRAZOLE": 3.623678752599519, "RASILEZ": 12.017358610443214, "TAMIFLU": 2.254653211398667, "TOBRAMYCIN": 25.58619062807742, "TRUVADA": 2.1369872937570418, "VFEND": 1.4242296538710553, "VIREAD": 12.033136367273626, "null": 1.0865307465622869}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2155.json
index 9ca8f80079b..113532f7246 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2155.json
@@ -1 +1 @@
-{"AMLODIPINE": 909.540138114541, "CAFFEINE": 1702.9612475917645, "ENTRESTO": 5.73173930702683, "LEVOFLOXACIN": 99.70604777908396}
\ No newline at end of file
+{"ABILIFY": 83.30602743376365, "null": 0.6959354118180171}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2156.json
index 630221a430a..9bc2c6e415a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2156.json
@@ -1 +1 @@
-{"ACLIDINIUM": 15.79355590154366, "ADALIMUMAB": 2.537939052994054, "AFINITOR": 9.87161685521753, "AMBRISENTAN": 76.48666038426065, "ARAVA": 2.949842769296088, "BUPIVACAINE": 41.77879428716924, "CICLOSPORIN": 1.8726571922654964, "COSENTYX": 2.0553382281969568, "CUBICIN": 12.116951230433182, "GLYCOPYRRONIUM": 44.63352807829998, "HYDROCORTISONE": 8.618088568997015, "LEFLUNOMIDE": 17.464828796730547, "LYRICA": 4.740154123889821, "MEPOLIZUMAB": 15.738117692230386, "NUCALA": 5.7458121102828015, "OMALIZUMAB": 3.4672233002103416, "XELJANZ": 1.0373622510192957, "null": 1.0040412499825295}
\ No newline at end of file
+{"null": 1.481424803110106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2157.json
index cc81d9c05b7..928345c2e05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2157.json
@@ -1 +1 @@
-{"COMIRNATY": 2.312765144319058}
\ No newline at end of file
+{"null": 1.3727476869860695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2158.json
index b2773e63a46..38158bbf792 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2158.json
@@ -1 +1 @@
-{"null": 2.141940521401468}
\ No newline at end of file
+{"ELIQUIS": 5.90707894021044, "JANUMET": 11.369676687240514, "null": 1.1912211904320988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2159.json
index f00f80a42e5..81631de30c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2159.json
@@ -1 +1 @@
-{"SOLIRIS": 24.64823357335205}
\ No newline at end of file
+{"ATAZANAVIR": 12.824482116299878, "BEDAQUILINE": 15.420153145337034, "COMIRNATY": 0.0451147605481075, "CRIXIVAN": 66.57269202135188, "FORSTEO": 4.602650583245115, "FORXIGA": 5.459629602704652, "JARDIANCE": 4.978922631598486, "NORVIR": 112.9198028176019, "OMALIZUMAB": 19.93196970302666, "REYATAZ": 184.74203164834915, "SIMPONI": 2.564949500129336, "null": 1.1919185147258982}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/216.json
index e4a8c1bda08..bbaca30ab26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/216.json
@@ -1 +1 @@
-{"null": 1.039897555002841}
\ No newline at end of file
+{"BLINATUMOMAB": 834.8174089825604, "CYTARABINE": 133.8200401887634, "KYMRIAH": 132.35339382448248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2160.json
index e333dfe1df4..9263fa5f5ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2160.json
@@ -1 +1 @@
-{"ABATACEPT": 2.701329679556612, "ACLIDINIUM": 2.3477185887780525, "ADALIMUMAB": 4.658734345125329, "AMGEVITA": 25.94744480358513, "AMINOSALICYLIC": 1.4381496193974153, "ARAVA": 1.2324905816766925, "AUBAGIO": 1.0281505099017847, "AZATHIOPRINE": 11.950131938261547, "BOTULINUM": 1.92724634903852, "BUDESONIDE": 4.224170457115733, "CERTOLIZUMAB": 17.213120896340417, "CIMZIA": 27.157010758511703, "COSENTYX": 10.749434728169051, "ENBREL": 2.5538235771452324, "ENTYVIO": 43.6110062316749, "FENTANYL": 2.2393354674762733, "HUMIRA": 18.85909146792432, "IDACIO": 13.828168476310458, "INFLECTRA": 17.075798827570043, "INFLIXIMAB": 21.018014706016675, "MERCAPTOPURINE": 6.492516271567511, "METHOTREXATE": 2.009539107045673, "MYCOPHENOLATE": 1.0975261900508282, "PANTOPRAZOLE": 2.275134595879334, "REMICADE": 19.046555825202717, "RINVOQ": 3.5153066016908654, "RISANKIZUMAB": 54.517793726689206, "SIMPONI": 4.203744622114032, "SKYRIZI": 4.50837570888682, "STELARA": 131.31561946596375, "USTEKINUMAB": 20.95645349985838, "VEDOLIZUMAB": 22.84430573938296, "XELJANZ": 2.335267815459164}
\ No newline at end of file
+{"SYNAGIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2161.json
index a4cc826e0f9..a4fcf8d5c33 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2161.json
@@ -1 +1 @@
-{"ERTAPENEM": 205.13037800670944, "IBUPROFEN": 12.554721648855711, "LEVOFLOXACIN": 5.449939383665131, "null": 5.287401002199151}
\ No newline at end of file
+{"OLANZAPINE": 84.77952203197465, "null": 0.6058546552497089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2162.json
index b62b1fe14db..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2162.json
@@ -1 +1 @@
-{"DARZALEX": 4305.221030728607}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2163.json
index b425bb746d4..2f1f75b64c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2163.json
@@ -1 +1 @@
-{"CIMZIA": 8.167740694539107, "SYNAGIS": 95.19822180250073, "null": 1.3896521054189217}
\ No newline at end of file
+{"null": 9.331349552867296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2164.json
index 02567f6ca69..4105854ba42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2164.json
@@ -1 +1 @@
-{"null": 2.5460556445726743}
\ No newline at end of file
+{"COMIRNATY": 0.2096046120253018, "null": 0.5402780772900334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2165.json
index ebd5123a91b..699f3515d26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2165.json
@@ -1 +1 @@
-{"ABILIFY": 1.699116354046842, "AERIUS": 1.5398574611529603, "ALLI": 15.518658075751198, "ARIPIPRAZOLE": 1.0351474652912724, "BENLYSTA": 1.785136963239724, "BEXSERO": 20.44550760353357, "BRINTELLIX": 4.961053742186953, "BRIVIACT": 2.861832751141752, "BUPRENORPHINE": 1.452783985433603, "CHAMPIX": 9.627748564363769, "CYMBALTA": 4.001296338277039, "FYCOMPA": 3.5104329365665867, "GARDASIL": 1.515312337306414, "HEXACIMA": 92.71839472572414, "HEXYON": 27.844182582473746, "INFANRIX": 39.158839085292406, "KAFTRIO": 1.645291780801445, "KEPPRA": 2.3069982361121424, "LATUDA": 5.783397321441616, "LEVETIRACETAM": 1.2541980178353118, "LYRICA": 1.8422987403402995, "MENVEO": 1.7941922352378283, "MIDAZOLAM": 1.0116851332701389, "MMRVAXPRO": 49.19719809230512, "NAGLAZYME": 1.9189288393037047, "NIMENRIX": 7.764145154594899, "NON": 35.775660033151794, "NOT": 4.117310786986261, "OMALIZUMAB": 1.0604218859659822, "PEGASYS": 2.001387773829051, "PEGINTRON": 1.0910805408625388, "PREVENAR": 30.895838871539688, "ROTARIX": 49.99577614566888, "ROTATEQ": 42.33107167521289, "SUBOXONE": 3.0007681073791224, "SYNAGIS": 12.579238864665786, "SYNFLORIX": 9.760082668090943, "TAMIFLU": 2.54104799896878, "TWINRIX": 1.0116398559062791, "XYREM": 1.3499158279860877, "null": 2.015615364465544}
\ No newline at end of file
+{"null": 0.5317756884446304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2166.json
index b9ce0cf946e..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2166.json
@@ -1 +1 @@
-{"HARVONI": 30.674879948406403, "PEGASYS": 21.537640796997987, "PEGINTERFERON": 27.820140695207844, "PEGINTRON": 28.02724341520697, "RIBAVIRIN": 40.89345089828407}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2167.json
index fd519b4f66a..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2167.json
@@ -1 +1 @@
-{"OMALIZUMAB": 166.34731400122325}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2168.json
index d4ccf3c855d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2168.json
@@ -1 +1 @@
-{"null": 1.5866082288418275}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2169.json
index f1e10be686b..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2169.json
@@ -1 +1 @@
-{"BUDESONIDE": 10.471984647199964, "CELLCEPT": 16.187594349916083, "CICLOSPORIN": 21.697413017966483, "DEXAMETHASONE": 17.69061819323598, "EFAVIRENZ": 77.55549317154102, "LAMIVUDINE": 67.57234709249312, "MYCOPHENOLATE": 49.16147166318974}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/217.json
index 1c5de850920..fb76784cefb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/217.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/217.json
@@ -1 +1 @@
-{"SPIKEVAX": 3.717820463072367}
\ No newline at end of file
+{"COMIRNATY": 1.1936094516971716, "SPIKEVAX": 1.2859179575513062, "TOZINAMERAN": 2.7950133221848867, "VAXZEVRIA": 2.7814005030852726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2170.json
index 0a310262353..d6f74b727b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2170.json
@@ -1 +1 @@
-{"ASPARAGINASE": 34.921023865416814, "COMBIVIR": 27.51490976451842, "KALETRA": 10.591188329042431, "KEPPRA": 6.459990192118634, "null": 3.845950705645684}
\ No newline at end of file
+{"null": 0.2558298307316865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2171.json
index c1a96127be6..51f1ca4e488 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2171.json
@@ -1 +1 @@
-{"ABACAVIR": 40.31127095948433, "CICLOSPORIN": 22.85363226950199}
\ No newline at end of file
+{"null": 0.7591107809894673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2172.json
index a5f50849015..e6dda3c1526 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2172.json
@@ -1 +1 @@
-{"AVAMYS": 382.83432380324575}
\ No newline at end of file
+{"AFINITOR": 6.824020122833124, "BYETTA": 3.9114837722627223, "CABOMETYX": 27.415175844514145, "DOCETAXEL": 5.907358770710211, "FASLODEX": 14.882679219191193, "IBRANCE": 23.027253589852585, "INLYTA": 10.024317565636322, "KEYTRUDA": 12.033635106357544, "LONSURF": 22.77968776464956, "NEXAVAR": 10.26437768483618, "STIVARGA": 17.15482893216877, "SUTENT": 8.96126384258416, "VOTRIENT": 3.3998452964372072, "XOFIGO": 58.61362665818138, "XTANDI": 19.53471988627772, "null": 0.2424673922729635}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2173.json
index d5e3f312178..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2173.json
@@ -1 +1 @@
-{"null": 3.6909512834391984}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2174.json
index 6158dbc3b75..d1c49d9dae3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2174.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 33.98188359258177, "null": 2.4389865954265604}
\ No newline at end of file
+{"CICLOSPORIN": 11.374852151479216, "ELIQUIS": 3.340248858875504, "KEYTRUDA": 11.257764479518537, "null": 1.1857426319796165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2175.json
index dc5d4c72e5c..e3ed6720a3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2175.json
@@ -1 +1 @@
-{"null": 1.3208610798247866}
\ No newline at end of file
+{"ADALIMUMAB": 0.1249604396117363, "AFINITOR": 0.558860519899027, "ALEMTUZUMAB": 2.0819576448605708, "ALIMTA": 0.9169294647785, "AMIKACIN": 19.01015777720368, "AMINOSALICYLIC": 0.8330499364056418, "ANIDULAFUNGIN": 44.95447980235934, "ANORO": 5.038645786684179, "ARAVA": 0.8252668367157724, "ASPARAGINASE": 5.918117277077505, "ATAZANAVIR": 1.5770836215916413, "ATEZOLIZUMAB": 10.793484208941113, "ATRIPLA": 0.0659911002900718, "AUBAGIO": 0.4438972504255105, "AZACITIDINE": 4.14091601393544, "AZATHIOPRINE": 2.846420148277303, "BEDAQUILINE": 6.310084126652108, "BENLYSTA": 0.8499968039506354, "BEVACIZUMAB": 4.3158449067761815, "BORTEZOMIB": 10.194915393785427, "BUDESONIDE": 1.8454644062187624, "BUSULFAN": 6.310729553280905, "BYETTA": 1.1947927916261858, "CAELYX": 2.6094743054828635, "CANCIDAS": 9.611115186967746, "CARMUSTINE": 5.469791678663731, "CASPOFUNGIN": 41.04627990913524, "CELLCEPT": 1.914247388329016, "CHAMPIX": 0.4092632873546568, "CICLOSPORIN": 3.494105245500501, "CIMZIA": 1.0179336025317358, "COMIRNATY": 0.0708127459607467, "COSENTYX": 6.043343837621177, "CRIXIVAN": 2.9999920749246627, "CUBICIN": 4.7311635423765965, "CYMBALTA": 0.4459124449176331, "CYTARABINE": 6.608983697144195, "DAPTOMYCIN": 21.135313253024226, "DEXAMETHASONE": 4.096932746649087, "DOCETAXEL": 1.3757761318917452, "ELIQUIS": 0.4033548179009453, "EMPAGLIFLOZIN": 25.41204143331916, "EPIVIR": 2.671800635708834, "EXJADE": 0.5516570394982888, "FORXIGA": 12.871699827951344, "GARDASIL": 0.6487140817955053, "HIZENTRA": 1.409358071429151, "HUMIRA": 2.798674361910032, "IBRANCE": 1.0775441528633, "IBUPROFEN": 1.011739847336946, "INFLIXIMAB": 3.014747463427676, "INLYTA": 1.220775774087001, "JAKAVI": 0.8668536496074307, "JANUVIA": 0.8642276948233045, "JARDIANCE": 15.830810436280908, "KALETRA": 1.0796286156296704, "KEPPRA": 0.7142280687062486, "KEYTRUDA": 0.3943651625495599, "KYMRIAH": 1.2589610574068768, "LEVOFLOXACIN": 1.55577366827951, "LOPINAVIR": 12.92411965409401, "MEPOLIZUMAB": 1.695616670928458, "METHOTREXATE": 1.424241605795549, "MICAFUNGIN": 32.02128236375394, "MYCAMINE": 30.64944417198894, "MYCOPHENOLATE": 1.5776082196973222, "NEULASTA": 2.610466698312362, "NEXAVAR": 0.3795814333958447, "NOT": 2.76320646320378, "NUCALA": 0.8485643624389875, "OMALIZUMAB": 1.0761760142143753, "PANTOPRAZOLE": 1.2497077971690456, "PEGASYS": 1.6051102105941673, "PEGINTERFERON": 1.6954497839509264, "PEGINTRON": 1.391257695539971, "POSACONAZOLE": 13.488552157105609, "RELVAR": 5.332213467043225, "REMICADE": 2.725382264414404, "RITUXIMAB": 2.426993288996871, "SIMPONI": 1.480228706913834, "SOLIRIS": 1.9602293596997948, "SPIKEVAX": 0.0518681665621749, "STELARA": 0.7908640856758751, "SUTENT": 1.416414930165932, "TACROLIMUS": 13.267752348376414, "TOZINAMERAN": 0.2454383584872591, "TRELEGY": 8.757039720671164, "VAXZEVRIA": 0.0992754593575697, "VFEND": 2.6185534434078788, "VORICONAZOLE": 9.04924073335292, "VOTRIENT": 1.038505256783835, "XELJANZ": 0.9065923763131152, "XOLAIR": 0.8703523899758486, "ZOSTAVAX": 0.7213818263076975, "ZYPREXA": 0.2692521038091962, "null": 1.08561185106506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2176.json
index 8e33f7ae9a1..8507704bf0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2176.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 149.01850558435518, "null": 1.170919195749385}
\ No newline at end of file
+{"CICLOSPORIN": 34.312234886198524, "null": 0.4322229410553051}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2177.json
index beb570a8fca..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2177.json
@@ -1 +1 @@
-{"CRIXIVAN": 193.18415333382933, "null": 3.135090396078424}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2178.json
index c22a81536ac..7e0e23dd051 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2178.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1212210701702252, "CYMBALTA": 18.455565138154967}
\ No newline at end of file
+{"BASILIXIMAB": 83.3389577531939, "CASPOFUNGIN": 51.16930604706874, "CYTARABINE": 27.2784983733701, "DOCETAXEL": 17.743435841229733, "JARDIANCE": 7.744272172589071, "null": 0.5792174732079649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2179.json
index 4f44698a156..66a53ab4840 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2179.json
@@ -1 +1 @@
-{"null": 1.2312581221146652}
\ No newline at end of file
+{"null": 0.4538027428168334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/218.json
index 3447df92225..5d0e83e70e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/218.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/218.json
@@ -1 +1 @@
-{"COMIRNATY": 6.486851146192079, "ELLAONE": 43.08668577799354, "OVITRELLE": 51.017414811595714, "SPIKEVAX": 2.3914589139178872, "TOZINAMERAN": 2.0413758384240026}
\ No newline at end of file
+{"null": 0.4636742409620902}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2180.json
index 4f64efe25da..53a90150e33 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2180.json
@@ -1 +1 @@
-{"GARDASIL": 6.300343591545618, "JARDIANCE": 9.687369916474385, "LEVETIRACETAM": 20.55012709141713}
\ No newline at end of file
+{"FORXIGA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2181.json
index e78bdce14f9..15ce7328f37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2181.json
@@ -1 +1 @@
-{"null": 1.4641793956652778}
\ No newline at end of file
+{"null": 3.771923135522707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2182.json
index 05101eedfaa..28c9315c5fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2182.json
@@ -1 +1 @@
-{"ATAZANAVIR": 59.02164351161097, "AVAMYS": 7.750653315880079, "BUDESONIDE": 15.412178040556698, "CICLOSPORIN": 2.193045275967615, "COBICISTAT": 128.47280675885344, "DARUNAVIR": 19.14370275938481, "DEXAMETHASONE": 2.305299583378042, "FLUTICASONE": 28.014714927562864, "GENVOYA": 58.80559164885881, "HYDROCORTISONE": 33.789931168865145, "ISENTRESS": 11.231368778758927, "KALETRA": 47.39549579301694, "LOPINAVIR": 105.20007554066, "MEPOLIZUMAB": 4.073352902390662, "NORVIR": 147.495289442233, "REYATAZ": 14.802245477305148, "RITONAVIR": 475.6644080728068, "STRIBILD": 1.4557653095136922, "null": 1.3639380213278898}
\ No newline at end of file
+{"CLOPIDOGREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2183.json
index 5ddb1b52eb5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2183.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.2172758626918685, "ATAZANAVIR": 29.346107220391357, "AZATHIOPRINE": 5.45094475326935, "BUDESONIDE": 7.706254919484505, "CELLCEPT": 4.773691828589302, "CICLOSPORIN": 9.257074000552214, "ENTYVIO": 16.90867591670899, "HYDROCORTISONE": 8.839438022693637, "KALETRA": 15.805901140143929, "LOPINAVIR": 68.69768971000836, "MEPOLIZUMAB": 13.0694424116693, "METHOTREXATE": 6.302913247816661, "MYCOPHENOLATE": 9.505314501869144, "NORVIR": 70.86810849352483, "NUCALA": 5.550538277420239, "RITONAVIR": 123.73437360705206, "null": 1.2347761722291593}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2184.json
index bd49e283fd6..184c74eaaa9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2184.json
@@ -1 +1 @@
-{"CICLOSPORIN": 19.76893075099348, "CIMZIA": 4.556434720007007, "COSENTYX": 7.431602326619571, "RINVOQ": 20.339623801921945, "SIMPONI": 3.8953830292173888, "STELARA": 15.99533942264466, "TREMFYA": 16.96927548812026}
\ No newline at end of file
+{"ANORO": 340.92076466197153, "COMIRNATY": 0.7484000431980344, "VAXZEVRIA": 0.6511639501381432, "null": 0.4590610488520156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2185.json
index c72787794d4..f6da83a786c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2185.json
@@ -1 +1 @@
-{"HUMALOG": 55.943347784993016, "INSULIN": 166.41215052670933, "LANTUS": 43.80262519404179}
\ No newline at end of file
+{"CICLOSPORIN": 18.439432388526377, "COMIRNATY": 0.8394511016056735, "SPIKEVAX": 0.4196857909549783, "VAXZEVRIA": 0.8703937154451249, "null": 0.667573940035191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2186.json
index 31e810e97d4..37d925c8ff3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2186.json
@@ -1 +1 @@
-{"CASPOFUNGIN": 623.8498639281297}
\ No newline at end of file
+{"COMIRNATY": 2.7537579841138364, "SPIKEVAX": 0.7936266540190284, "VAXZEVRIA": 1.332128774245385, "null": 0.4618812129518559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2187.json
index a1468641c6b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2187.json
@@ -1 +1 @@
-{"BENLYSTA": 18.58318381084857, "IBRANCE": 3.2328293783195527, "STELARA": 7.183607367704875, "null": 1.220529925910126}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2188.json
index 9ce2b984f42..7a3262b24ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2188.json
@@ -1 +1 @@
-{"ARAVA": 1.3121828345554931, "KEYTRUDA": 5.051036220137024, "MEKINIST": 15.40497449953932, "PEGASYS": 8.232388210848448, "PEGINTERFERON": 80.12832841453931, "PEGINTRON": 8.350869435698465, "REBETOL": 70.93362642569758, "RIBAVIRIN": 49.87616868919748}
\ No newline at end of file
+{"BUSULFAN": 6.665657163890091, "CICLOSPORIN": 3.713189647631365, "CLOFARABINE": 113.56356207144614, "COMIRNATY": 0.3588505886853784, "DINUTUXIMAB": 325.70387410689574, "EVOLTRA": 391.6026821910266, "FILGRASTIM": 33.26666426524781, "IPILIMUMAB": 9.122397677917748, "KEYTRUDA": 2.565137337670306, "KYMRIAH": 25.71118295925762, "NEULASTA": 22.197032567138663, "QARZIBA": 746.5600635311396, "SPIKEVAX": 0.2392801220674749, "TOZINAMERAN": 0.4341119194995955, "VAXZEVRIA": 0.6573547462604288, "YONDELIS": 78.05570506736963, "null": 0.7468713156989557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2189.json
index 0f601593120..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2189.json
@@ -1 +1 @@
-{"null": 1.9147619606564508}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/219.json
index e3d5eb5146a..68a074c4215 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/219.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/219.json
@@ -1 +1 @@
-{"GONALF": 712.1203333410441, "OVITRELLE": 591.9121127087847, "null": 1.024567463334371}
\ No newline at end of file
+{"VAXZEVRIA": 1.0936291867571517, "null": 0.2661544941652311}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2190.json
index c9299601c93..c71f386853d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2190.json
@@ -1 +1 @@
-{"COSENTYX": 6.216520658971286, "IRESSA": 34.78099360469639, "KEYTRUDA": 3.743584237369833}
\ No newline at end of file
+{"COMIRNATY": 0.9753238267997456, "null": 0.5633666386402757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2191.json
index f2a64b87b9e..ce1f362d4b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2191.json
@@ -1 +1 @@
-{"APIDRA": 1.8296284505073035, "APROVEL": 11.180446097799289, "BYDUREON": 1.9372154143205784, "COSENTYX": 2.503334291939256, "CUBICIN": 7.300895969521969, "ELIQUIS": 2.325476273167107, "ENTYVIO": 3.0080387529807835, "ESOMEPRAZOLE": 3.151614592849884, "EXJADE": 1.4975590330192294, "HUMIRA": 1.235536272716922, "INCIVO": 2.1099434692166, "IPILIMUMAB": 5.026146201745092, "JANUVIA": 1.5796957348648937, "LEVOFLOXACIN": 1.2290145781189992, "LITAK": 84.4335224071629, "NEXAVAR": 1.559962754245936, "NOVONORM": 8.597949967501325, "PEGINTERFERON": 2.0604717485991317, "PREGABALIN": 4.231606036991863, "RITUXIMAB": 1.750321926584406, "ROACTEMRA": 5.666156588459383, "SIMPONI": 4.111009394232265, "STELARA": 4.006131818011896, "TAGRISSO": 3.395635663936643, "THALIDOMIDE": 5.137814944953071, "XOLAIR": 1.5044117649125406, "null": 1.7703392359599432}
\ No newline at end of file
+{"null": 0.7163965810284204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2192.json
index 76e939e29c8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2192.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 165.522126255569}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2193.json
index d0efa013ffd..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2193.json
@@ -1 +1 @@
-{"null": 2.154150020697041}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2194.json
index f114b9cb191..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2194.json
@@ -1 +1 @@
-{"VIAGRA": 706.0198119716691}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2195.json
index 9df0309fc1a..59a736ed773 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2195.json
@@ -1 +1 @@
-{"AERIUS": 1.512077589543774, "AMIKACIN": 1.6798580173131634, "BEXSERO": 12.376612908596352, "BOSENTAN": 6.182629087370977, "BRIDION": 4.184890752666892, "BUDESONIDE": 1.270725512004604, "BUPIVACAINE": 4.441604940448888, "CAELYX": 3.906544149440784, "DEXAMETHASONE": 1.0698264211501676, "ENOXAPARIN": 3.4766691810140973, "FENTANYL": 2.88588155336766, "FLEBOGAMMA": 11.46729900976664, "GARDASIL": 1.7338279448211031, "HEXYON": 11.405362204928052, "HUMAN": 1.517758591670136, "HYDROCORTISONE": 1.565307804508989, "INFANRIX": 11.905728526931576, "IRBESARTAN": 1.3372764298506516, "KALETRA": 1.7904558468499123, "KIOVIG": 11.3570530146945, "MENVEO": 2.1835449777317977, "MIDAZOLAM": 2.1236655575099395, "MIRCERA": 2.059716480990238, "MMRVAXPRO": 3.855174341627112, "NAGLAZYME": 14.11580667249142, "NIMENRIX": 2.734425840642007, "NOT": 4.385067069084985, "ONCASPAR": 3.650769378524246, "POPPERS": 17.362298828950816, "PREGABALIN": 1.8111308947503275, "PREVENAR": 14.652702315393851, "PRIVIGEN": 4.118398060471376, "PROPRANOLOL": 2.687263086803661, "RISPERIDONE": 3.040803128395842, "ROTARIX": 38.8852798724276, "ROTATEQ": 5.36311115761145, "SEEBRI": 17.006274048108452, "SILDENAFIL": 1.7953460507252208, "SPINRAZA": 1.472575743340559, "SUFENTANIL": 3.114022813421758, "SYNAGIS": 17.849878465231114, "SYNFLORIX": 15.050539805386926, "TRACLEER": 3.1986955306397427, "TWINRIX": 1.8505280643127289, "VAXZEVRIA": 1.2658678688760965, "null": 2.958375563029909}
\ No newline at end of file
+{"AVASTIN": 10.30690396363387, "COMIRNATY": 0.0871890900602571, "KEYTRUDA": 2.618085061259877, "LYNPARZA": 312.5016257055552, "OLAPARIB": 103.59709160310312, "RUBRACA": 822.8072402865545, "ZEJULA": 280.8305434214498, "null": 0.2738177900442541}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2196.json
index cdfe7e45b68..efa354f49ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2196.json
@@ -1 +1 @@
-{"MMRVAXPRO": 24.479392325066605, "null": 2.8695673302871256}
\ No newline at end of file
+{"AFINITOR": 33.68865787589469, "DENOSUMAB": 115.4651345882878, "DOCETAXEL": 13.519236850514938, "FASLODEX": 67.47630375907038, "FULVESTRANT": 167.89368010621092, "IBRANCE": 24.36462699484826, "KISQALI": 43.474940418134246, "RIBOCICLIB": 358.6665543722972, "null": 0.0514345969528363}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2197.json
index 5f0672634eb..17bd54c2cba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2197.json
@@ -1 +1 @@
-{"null": 4.442290807349576}
\ No newline at end of file
+{"LONSURF": 42.57335920705888, "PEGASYS": 4.272514641406242, "STIVARGA": 39.69305559320301, "null": 0.3589019007242215}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2198.json
index 8e1da12e16c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2198.json
@@ -1 +1 @@
-{"null": 2.863469777983985}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2199.json
index 6c120d4034c..67c09efec54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2199.json
@@ -1 +1 @@
-{"ABATACEPT": 2.965356649095945, "ADALIMUMAB": 1.1718014153081573, "AFINITOR": 1.0782307226627237, "ARAVA": 1.3615198204047207, "BIKTARVY": 4.530478312022907, "BYDUREON": 2.459582049628099, "BYETTA": 2.294999103102726, "CELLCEPT": 1.6768542891691616, "CIMZIA": 1.766158500185875, "COMBIVIR": 4.001906726626326, "COSENTYX": 2.2259686668919585, "ELIQUIS": 1.3898851572090165, "EMPAGLIFLOZIN": 11.757929021535752, "ENBREL": 2.812616257494577, "FORSTEO": 1.4833459505937363, "GARDASIL": 1.397303424610962, "HUMIRA": 1.5877896219951373, "IBRANCE": 1.6152568772681826, "JANUMET": 1.5685390883393864, "JANUVIA": 1.5778505378904362, "KALETRA": 2.8369020850759097, "LYRICA": 1.8042316838554444, "MEPOLIZUMAB": 3.0854002127379943, "OMALIZUMAB": 1.5502150972243744, "PEGASYS": 1.406796916478302, "PEGINTRON": 1.2298813693322377, "ROACTEMRA": 2.2720829103468296, "SIMPONI": 2.8751909269896183, "STELARA": 1.7099737724333688, "XELJANZ": 4.111349649791503, "XOLAIR": 1.79185248524311, "ZOSTAVAX": 1.3572936696730524}
\ No newline at end of file
+{"FASLODEX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/22.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/22.json
index 1ea2e0e6475..3e7b945a8cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/22.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/22.json
@@ -1 +1 @@
-{"NOVOSEVEN": 156.82509829685773, "null": 1.0358951003265198}
\ No newline at end of file
+{"CIMZIA": 7.965344055111967, "null": 1.2501363462095068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/220.json
index abbfc7aae4f..b5016276e41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/220.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/220.json
@@ -1 +1 @@
-{"BYETTA": 48.555329636039154, "JANUMET": 40.57961119185602}
\ No newline at end of file
+{"COMIRNATY": 0.7078883740236062, "null": 0.9114919797986382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2200.json
index a996a42db7f..f1f1356cfdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2200.json
@@ -1 +1 @@
-{"AZTREONAM": 291.21197508291993, "CANNABIDIOL": 92.85989836104471, "CAYSTON": 976.0342656398344, "HUMIRA": 8.24993517984446, "KAFTRIO": 191.58883546167337, "KALYDECO": 602.1557235459907, "ORKAMBI": 856.1778460442332, "SYNAGIS": 10.57188178268562, "TOBI": 706.7825124193597, "TOBRAMYCIN": 77.28903628029178, "XOLAIR": 3.899683002506681}
\ No newline at end of file
+{"IBRANCE": 90.9655402312428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2201.json
index 4b9cbdbda13..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2201.json
@@ -1 +1 @@
-{"ORKAMBI": 1762.147212870255}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2202.json
index c8f5d9445e1..6221529bc1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2202.json
@@ -1 +1 @@
-{"null": 1.2060823558289395}
\ No newline at end of file
+{"null": 1.2741546040657432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2203.json
index 2f54625afb8..98424013fa2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2203.json
@@ -1 +1 @@
-{"KALYDECO": 1163.827272484795, "ORKAMBI": 4273.055114918833}
\ No newline at end of file
+{"ARAVA": 15.24228403246938, "null": 0.6502256512287952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2204.json
index 6b4a0e5e1bf..b2fa4d72ab1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2204.json
@@ -1 +1 @@
-{"BEDAQUILINE": 144.7026977687118}
\ No newline at end of file
+{"ARAVA": 4.879104536881315, "DOCETAXEL": 14.259758772707125, "EXJADE": 8.212779660713503, "FENTANYL": 5.260819469289019, "GARDASIL": 3.3159886533305967, "KYMRIAH": 21.223514497999616, "null": 1.072954508352228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2205.json
index 6e090d429ba..2095c2ff806 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2205.json
@@ -1 +1 @@
-{"AFINITOR": 1.333356493684056, "ALISKIREN": 45.17170950493468, "ASPARAGINASE": 7.2690700648376225, "AUBAGIO": 2.9962759260341665, "AYESURBY": 286.7213948366054, "BELIMUMAB": 5.0608465792277615, "BENLYSTA": 2.3083500739572926, "BETMIGA": 9.102223441629466, "BYETTA": 1.6150300237774666, "CELECOXIB": 5.055485003510575, "CELLCEPT": 1.0864039788251951, "CIMZIA": 1.8916339148016263, "CLOPIDOGREL": 5.500564599054324, "COSENTYX": 1.760442164485975, "DULOXETINE": 3.403768302647122, "ELIQUIS": 1.0438795254061712, "EMPAGLIFLOZIN": 7.275308835706903, "ENTYVIO": 1.2492964812872434, "ESBRIET": 3.119046808669999, "EVISTA": 1.5392487393160337, "EXJADE": 1.676191476634105, "FAMPYRA": 17.701344104971934, "FASENRA": 1.570729776804707, "FASLODEX": 1.1224977791236026, "FIRDAPSE": 1.6389775080414666, "FORSTEO": 1.877834032513315, "FORXIGA": 9.618313294933923, "GARDASIL": 1.4747636899579866, "HERCEPTIN": 1.2391353459166103, "HIZENTRA": 2.402208281316053, "HUMALOG": 1.5428391836832476, "HUMIRA": 6.0555362823051455, "IBRANCE": 2.1648941760714444, "IRESSA": 1.7037729050464203, "JAKAVI": 1.5572953594860115, "JANUMET": 1.020962665730913, "JARDIANCE": 10.212584493408531, "LANTUS": 1.053256831497412, "LEMTRADA": 1.6047337185712711, "LYRICA": 1.736572703627286, "METHOTREXATE": 2.018333717302362, "MICARDIS": 3.1682360593041827, "NUCALA": 7.1193810432333375, "OCRELIZUMAB": 9.502557385770825, "OMALIZUMAB": 1.821835365162081, "OPSUMIT": 1.092723131972044, "ORENCIA": 7.194059560977343, "OXYBUTYNIN": 4.537729432017505, "PEGASYS": 1.3514406178091125, "PEGINTRON": 1.0562022049507451, "PLEGRIDY": 1.6118031550546104, "REMICADE": 2.143705703833588, "REVATIO": 1.8408514019153808, "RITUXIMAB": 1.627602417332108, "ROACTEMRA": 2.3483100403950345, "SAXENDA": 1.022190527644241, "SIMPONI": 2.1310052076576023, "STELARA": 1.2805634892820137, "TOVIAZ": 11.190037512622222, "TRACLEER": 1.477270468697178, "TRELEGY": 1.529063507505759, "TREMFYA": 2.2070660582060686, "VELTASSA": 1.6979295474519167, "XELJANZ": 6.146524586519368, "XTANDI": 2.7696308003593666, "ZOSTAVAX": 1.0074050660223268}
\ No newline at end of file
+{"COMIRNATY": 0.0801363536338931, "ESBRIET": 13.028409758277713, "FENTANYL": 5.10909609500778, "TRACLEER": 14.45324761587982, "null": 1.3253362621784908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2206.json
index f77f52e6c02..28e82fcc0d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2206.json
@@ -1 +1 @@
-{"ASPARAGINASE": 710.7920020275193}
\ No newline at end of file
+{"SPIKEVAX": 24.28435341930962}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2207.json
index 36142ae7901..e7b59fb53a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2207.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 9.668588880133129, "ASPARAGINASE": 6.655472784189851, "BASILIXIMAB": 21.471801644819102, "BORTEZOMIB": 6.279403976036073, "BRILIQUE": 4.108759857217241, "BUDESONIDE": 4.282378186855326, "BUSILVEX": 97.63855129890494, "BUSULFAN": 217.53504642696905, "CARMUSTINE": 15.226128801722451, "CELLCEPT": 8.66296791371324, "CICLOSPORIN": 22.836400861869787, "CYTARABINE": 8.201168753931636, "DEFITELIO": 116.9428865386252, "DEXAMETHASONE": 2.5748017398969987, "ELIQUIS": 1.3758170658984044, "FORXIGA": 6.090763236179657, "HALAVEN": 7.96119926418608, "IRESSA": 24.063605984710385, "JAKAVI": 2.962974964257364, "JARDIANCE": 2.496940674395949, "JEVTANA": 10.950967666655863, "MELPHALAN": 19.226264651319976, "METHOTREXATE": 2.878927827237539, "MYCOPHENOLATE": 9.580642855830051, "RITUXIMAB": 2.4269923112699123, "THIOTEPA": 41.35647694111013, "VFEND": 2.06393136575977}
\ No newline at end of file
+{"null": 2.4110022237442075}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2208.json
index 2f537f878e7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2208.json
@@ -1 +1 @@
-{"GARDASIL": 3.785367848051517, "INSULIN": 35.506549893734444}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2209.json
index ec3d4ce1e3b..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2209.json
@@ -1 +1 @@
-{"COMIRNATY": 3.914604353285155, "COSENTYX": 2.509603929525813, "FAMPYRA": 29.185509481656677, "JARDIANCE": 4.860290388643475, "KESIMPTA": 32.19185824680456, "KEYTRUDA": 1.3107353386409757, "SPIKEVAX": 1.6400490979390825, "VAXZEVRIA": 1.3367642615833708}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/221.json
index a9c2b13dec8..32352c9cd0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/221.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/221.json
@@ -1 +1 @@
-{"null": 1.671936358066331}
\ No newline at end of file
+{"ABACAVIR": 0.3758410730679603, "ADCETRIS": 90.6629433602092, "ALEMTUZUMAB": 1.3859520971175243, "ALIMTA": 0.8680149840321356, "ARANESP": 1.0262328090606248, "ARAVA": 0.0584000191542375, "ARSENIC": 83.77124325345295, "ASPARAGINASE": 6.873000715560991, "AVASTIN": 3.084548536380254, "AZACITIDINE": 74.73891875752705, "AZATHIOPRINE": 1.360989104291519, "BEVACIZUMAB": 3.294756157381137, "BORTEZOMIB": 5.891836545351418, "BUSILVEX": 19.24598785197774, "BUSULFAN": 10.566208637525683, "CAELYX": 16.416231902655245, "CANCIDAS": 10.760892781397724, "CAPECITABINE": 1.800921505281785, "CARMUSTINE": 42.75859542468945, "CASPOFUNGIN": 3.762917777509261, "CELECOXIB": 3.89436213905457, "CELLCEPT": 1.6779899684237136, "CHLORMETHINE": 276.43165638827986, "CICLOSPORIN": 4.444251429714038, "CLADRIBINE": 26.95991085574286, "CLOFARABINE": 31.76048968967356, "COMBIVIR": 1.2886155140277469, "COMIRNATY": 0.0383443849316066, "CYTARABINE": 18.521110045737835, "DASATINIB": 4.706006480316533, "DECITABINE": 64.1466668154165, "DEFITELIO": 21.37375107424446, "DEXAMETHASONE": 3.9709771811867136, "DOCETAXEL": 8.81641094338189, "DOXORUBICIN": 11.517938374911369, "ELIQUIS": 0.1443214932964592, "EXJADE": 18.52721990152359, "FILGRASTIM": 14.557095345878752, "GARDASIL": 0.2387650858019673, "HERCEPTIN": 5.563235931985917, "HUMIRA": 0.7145676285148611, "HYDROXYCARBAMIDE": 30.41008111356076, "ICLUSIG": 2.062949410630812, "IMBRUVICA": 5.135367043699268, "IRINOTECAN": 7.017169935799589, "JAKAVI": 29.867327429083023, "KEPPRA": 0.2433170902894919, "KEYTRUDA": 0.5403702067155478, "KYMRIAH": 1.7098606233922111, "LYNPARZA": 25.178493153297406, "MABTHERA": 4.141104142459735, "MELPHALAN": 9.619746996967937, "MERCAPTOPURINE": 13.278583353972556, "METHOTREXATE": 4.304252452313631, "MIDOSTAURIN": 31.715570770834983, "NEULASTA": 2.970203081668104, "NEXAVAR": 1.9652806737040895, "NOXAFIL": 24.785084851839628, "NPLATE": 17.345181884714155, "OLAPARIB": 18.23616333143703, "PACLITAXEL": 4.770223754526268, "RADIOTHERAPY": 133.503888480076, "REMICADE": 2.6111007580044947, "REVLIMID": 10.036932251202735, "RITUXIMAB": 4.825360060366488, "ROACTEMRA": 0.7314840806200041, "RUBRACA": 2.0236207879988832, "RUXOLITINIB": 16.14233706205119, "RYDAPT": 21.11643262684059, "SOLIRIS": 2.274366398299472, "SPIKEVAX": 0.03635127579933, "SPRYCEL": 0.970932912881454, "STELARA": 0.5685879700783035, "SUTENT": 0.1549922766403108, "TASIGNA": 1.7130317916614637, "TAXOTERE": 24.392855630902638, "TEMODAL": 4.697469622613545, "TEMOZOLOMIDE": 16.04641485252656, "THALIDOMIDE": 5.498676222119293, "TOZINAMERAN": 0.061995564370902, "VAXZEVRIA": 0.0187360095934516, "VENCLYXTO": 45.275267894327605, "VENETOCLAX": 88.63350198770678, "VFEND": 18.24100091948522, "VIDAZA": 84.36671642793335, "VYXEOS": 24.820892408198187, "YESCARTA": 3.5334053952819207, "null": 0.9296636365492162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2210.json
index 9cecd026769..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2210.json
@@ -1 +1 @@
-{"null": 1.244470496613888}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2211.json
index 4b7c7a75cca..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2211.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 77.784604009242, "BUSULFAN": 115.02302626300973, "CELLCEPT": 30.51272700097987, "CICLOSPORIN": 20.80635791361986}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2212.json
index 1fdacf573f4..8bb70dda524 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2212.json
@@ -1 +1 @@
-{"null": 1.0385229700242975}
\ No newline at end of file
+{"null": 1.5246988716777894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2213.json
index 1a31b00163e..b8a74092c6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2213.json
@@ -1 +1 @@
-{"ACLASTA": 208.705853387233, "FORSTEO": 9.60153123624882, "ZOSTAVAX": 12.482295013046157, "null": 1.709341753973268}
\ No newline at end of file
+{"AFINITOR": 9.251068153288362, "AVASTIN": 18.77938066823662, "BEVACIZUMAB": 20.610920677614256, "BRAFTOVI": 13.05382402111739, "CAPECITABINE": 14.027594103980922, "CAPRELSA": 73.06501686625204, "COMIRNATY": 0.0775892421720339, "FASLODEX": 6.596380498070178, "FULVESTRANT": 45.536884449964, "IBRANCE": 7.346410867174251, "IRESSA": 27.00912365139867, "IRINOTECAN": 16.184588847757176, "KEYTRUDA": 3.885127382447534, "KISQALI": 16.59629328567184, "LONSURF": 42.55156315410201, "PANITUMUMAB": 71.55271718577454, "RIBOCICLIB": 39.950177391668255, "STIVARGA": 85.28076811996347, "TAGRISSO": 42.61673227311675, "null": 0.3211691015151969}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2214.json
index 71c49d92681..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2214.json
@@ -1 +1 @@
-{"APIDRA": 18.28054947007877, "BRAFTOVI": 27.702178957664, "EYLEA": 22.44112680198683, "NEPAFENAC": 1901.787519708332, "NEVANAC": 301.8571052958036}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2215.json
index 5f113dd5602..a18c987a0dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2215.json
@@ -1 +1 @@
-{"CYTARABINE": 16.441332592410845, "null": 2.4205435959050567}
\ No newline at end of file
+{"null": 16.400336870827847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2216.json
index deaecce560e..41af14f5f91 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2216.json
@@ -1 +1 @@
-{"ABRAXANE": 137.05939990758466, "BOSULIF": 61.93299498831032, "BOSUTINIB": 568.5689002458265, "CYTARABINE": 7.301649011767729, "DASATINIB": 936.66730643815, "GLIVEC": 121.67699341122147, "ICLUSIG": 19.693262216928247, "IMATINIB": 551.4544893422169, "NILOTINIB": 695.3249029532374, "TASIGNA": 104.52596741157228}
\ No newline at end of file
+{"FENTANYL": 30.776140111451657, "LUTATHERA": 729.9988052503513, "LUTETIUM": 1264.3536851062606, "null": 0.970319632433248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2217.json
index 63fe10f2869..2d438d4ec7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2217.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2217.json
@@ -1 +1 @@
-{"ANAKINRA": 4.4683023572488585, "ASPARAGINASE": 1.036421999531392, "ATEZOLIZUMAB": 6.166153471434932, "AXICABTAGENE": 532.035408602709, "BLINATUMOMAB": 60.497231790518974, "BLINCYTO": 70.70118927729445, "BORTEZOMIB": 3.2098951539082066, "BREYANZI": 794.6843891100432, "BUSULFAN": 2.2463588051073278, "CARFILZOMIB": 6.114551900210716, "COTELLIC": 2.0423892588583823, "CYTARABINE": 4.605035216977831, "DARZALEX": 2.1422815053123103, "DESCOVY": 5.034159612622109, "DEXAMETHASONE": 3.653095420792632, "DOXORUBICIN": 5.501413541788695, "EPCORITAMAB": 379.7417768100353, "GAZYVARO": 7.439178634620165, "GLOFITAMAB": 625.5810417020712, "IPILIMUMAB": 2.778727039835094, "KEYTRUDA": 2.5720906417111187, "KYMRIAH": 586.2176351714313, "LENALIDOMIDE": 7.979222337271628, "LISOCABTAGENE": 608.0119262676772, "MEKINIST": 1.8308250525545504, "NIVOLUMAB": 9.860012062117296, "OBINUTUZUMAB": 4.613834293176742, "OPDIVO": 11.937667423042948, "PEMBROLIZUMAB": 3.161227625280937, "QARZIBA": 12.1959651985146, "RITUXIMAB": 3.121974456147579, "RIXATHON": 5.886648882569596, "TISAGENLECLEUCEL": 372.884739585333, "TOCILIZUMAB": 4.824919427073132, "YESCARTA": 1132.215433833366}
\ No newline at end of file
+{"null": 1.6512278057843617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2218.json
index e4630c98a3a..ac8e3fd6146 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2218.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2218.json
@@ -1 +1 @@
-{"APREMILAST": 66.60349547674689, "AXICABTAGENE": 207.16301814372397, "BUDESONIDE": 5.149095734758227, "JAKAVI": 25.907490161652994, "KEYTRUDA": 13.275921568041484, "KYMRIAH": 35.87193091251117, "TOZINAMERAN": 1.7635993194306443, "YESCARTA": 113.96681113744314}
\ No newline at end of file
+{"AFINITOR": 35.26055695164124, "LUTATHERA": 372.307967345474, "null": 1.7698786637093746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2219.json
index d3f1e91f048..a2749add029 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2219.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2219.json
@@ -1 +1 @@
-{"ARAVA": 9.794604072561938}
\ No newline at end of file
+{"AFINITOR": 25.12297879041613, "FENTANYL": 9.239367697042294, "PANTOPRAZOLE": 111.22385372846182, "SUTENT": 3.3841956467457885, "null": 1.9262724059525929}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/222.json
index 92e012814c3..3fc56aeb271 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/222.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/222.json
@@ -1 +1 @@
-{"ACE": 3589.959076313897, "null": 1.125430266136171}
\ No newline at end of file
+{"ALEMTUZUMAB": 8.45271162564363, "AZACITIDINE": 311.6572599101515, "BUSULFAN": 55.11679271208983, "CICLOSPORIN": 21.351144153470777, "CLADRIBINE": 44.4351582225848, "CLOFARABINE": 66.45208138161259, "CYTARABINE": 154.0440395667228, "EXJADE": 3.18253852827501, "FILGRASTIM": 24.1706337116965, "JAKAVI": 5.065169889454023, "MIDOSTAURIN": 193.72812723359, "RYDAPT": 145.84955215907334, "VENCLYXTO": 31.57815753876872, "VENETOCLAX": 116.81213716430454, "VFEND": 5.551240884017208, "null": 0.5955030425445402}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2220.json
index d97fdf617f6..0a333d07d66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2220.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2220.json
@@ -1 +1 @@
-{"ABACAVIR": 8.867005244954214, "ALEMTUZUMAB": 16.31098753697818, "ASPARAGINASE": 50.82124813042773, "AZATHIOPRINE": 10.984491409074597, "BORTEZOMIB": 18.99505866791836, "BUSULFAN": 61.42438269606701, "CELLCEPT": 13.930709833090246, "CICLOSPORIN": 14.119206796792126, "COMBIVIR": 24.145635615040327, "CYTARABINE": 19.10429481247694, "DEXAMETHASONE": 13.397115501426963, "DOXORUBICIN": 9.996029640662906, "EFAVIRENZ": 28.53714859118922, "GANCICLOVIR": 149.11839336348416, "KALETRA": 7.165709482072099, "MERCAPTOPURINE": 56.61821124982143, "METHOTREXATE": 4.621902530687314, "MYCOPHENOLATE": 10.453757484435751, "OBINUTUZUMAB": 38.14957595414204, "RITUXIMAB": 14.404498995273988}
\ No newline at end of file
+{"null": 0.8839493325626656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2221.json
index 6621404ac2b..4f7cb8d6fae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2221.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2221.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 8.75983465290404, "BASILIXIMAB": 80.2799663194893, "BUDESONIDE": 2.847438057283888, "BUSULFAN": 8.628847777560736, "CELLCEPT": 27.404357297865914, "CICLOSPORIN": 20.29013916433593, "CIDOFOVIR": 162.29863038383192, "DASATINIB": 177.66352117147068, "ENTYVIO": 8.801311563677947, "GANCICLOVIR": 163.57203200345444, "INFLIXIMAB": 71.0134433706757, "MYCOPHENOLATE": 49.00925824957943, "RINVOQ": 8.032653373812398, "SPRYCEL": 7.747378279755652, "STELARA": 2.9818221076560363}
\ No newline at end of file
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2222.json
index ca203c9a3c6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2222.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2222.json
@@ -1 +1 @@
-{"GANCICLOVIR": 140.93962494464978}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2223.json
index 523291dc925..27758240a93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2223.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2223.json
@@ -1 +1 @@
-{"BASILIXIMAB": 75.69565398023317, "CELLCEPT": 57.322939558640336, "CICLOSPORIN": 7.936084852724999, "ENTYVIO": 17.604648125731924, "GANCICLOVIR": 49.528379822420405, "KEYTRUDA": 6.346603054590008, "OPDIVO": 13.245436749455424, "REMICADE": 51.1697142267506, "SPRYCEL": 20.096597514153}
\ No newline at end of file
+{"null": 0.7618228783228234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2224.json
index a55a4257bb4..ea8618f1c46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2224.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2224.json
@@ -1 +1 @@
-{"CELLCEPT": 47.88151024864813, "CICLOSPORIN": 16.554402454853285, "GANCICLOVIR": 168.0671433188008}
\ No newline at end of file
+{"null": 0.8652203883472588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2225.json
index e6c8e14b24b..87c0bda3596 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2225.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2225.json
@@ -1 +1 @@
-{"CELLCEPT": 46.21942754099628, "CICLOSPORIN": 23.76101966861085}
\ No newline at end of file
+{"AFINITOR": 124.09688449829794, "null": 0.4140489676554496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2226.json
index bcfde0c7ee8..14f8d5fa251 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2226.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2226.json
@@ -1 +1 @@
-{"CICLOSPORIN": 25.48893380412885}
\ No newline at end of file
+{"AUBAGIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2227.json
index 28f247cff08..9cca594b151 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2227.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2227.json
@@ -1 +1 @@
-{"CELLCEPT": 22.83854452966295, "CICLOSPORIN": 11.74105709348279, "GANCICLOVIR": 132.7945815142211}
\ No newline at end of file
+{"GARDASIL": 46.591445822586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2228.json
index 9b2bd031258..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2228.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2228.json
@@ -1 +1 @@
-{"ADVAGRAF": 18.197586265690884, "ALEMTUZUMAB": 49.749617055749, "AMIKACIN": 2.975346064102555, "ASPARAGINASE": 3.870452423293704, "ATEZOLIZUMAB": 19.074988087482023, "AZATHIOPRINE": 8.515328653531174, "BASILIXIMAB": 104.89790707437676, "BIKTARVY": 1.8934816444383893, "BLINCYTO": 20.6074411769849, "BORTEZOMIB": 4.08196517042233, "BUDESONIDE": 1.313617380120048, "BUSILVEX": 194.71393876786763, "BUSULFAN": 63.95201148293373, "CARMUSTINE": 5.424477503338146, "CASPOFUNGIN": 8.666116507746466, "CELLCEPT": 61.557429292983485, "CICLOSPORIN": 33.98016532485754, "CIDOFOVIR": 41.440928314154455, "COMBIVIR": 2.597041743714282, "CYTARABINE": 4.791314898670538, "DARZALEX": 7.007128234211858, "DEXAMETHASONE": 3.5737760299059693, "DOXORUBICIN": 2.8757821022014247, "ENTYVIO": 4.111266563308093, "EVEROLIMUS": 14.298008998173785, "GANCICLOVIR": 60.69375850001629, "HUMAN": 3.6848678315302, "HUMIRA": 1.3227915961645471, "INFLIXIMAB": 6.990865477225045, "ISENTRESS": 4.535876322948589, "JAKAVI": 4.120587164646631, "KALETRA": 2.1118791651262017, "KYMRIAH": 3.52619971716912, "KYPROLIS": 2.827877298428241, "LAMIVUDINE": 4.344323192341329, "LEMTRADA": 1.786263541349076, "MABCAMPATH": 73.15110159435204, "MABTHERA": 3.8908767942613873, "MELPHALAN": 11.41128180888587, "MERCAPTOPURINE": 16.161915598474675, "METHOTREXATE": 2.704358660341864, "MYCOPHENOLATE": 49.11547792337547, "NOT": 3.03590129454706, "OBINUTUZUMAB": 11.536225675524626, "OPDIVO": 1.2711846693433908, "RAPAMUNE": 6.987375344366411, "REMICADE": 4.11502091357783, "RINVOQ": 2.3235527049488804, "RITUXIMAB": 4.506930796395857, "ROTATEQ": 2.1144566738048844, "RUXOLITINIB": 15.936931540109356, "SIMPONI": 1.145282238864202, "SOLIRIS": 2.962784070128101, "SPRYCEL": 1.855240841182472, "STELARA": 1.800398477425187, "TACROLIMUS": 15.157237278663734, "TEMODAL": 3.5366449631525554, "TRIUMEQ": 4.6028622834965125, "VFEND": 1.8755868174032209}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2229.json
index 002f2cac66f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2229.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2229.json
@@ -1 +1 @@
-{"ABATACEPT": 1.2039374433151997, "ALEMTUZUMAB": 123.14195675160046, "AZACITIDINE": 8.56835259258077, "AZATHIOPRINE": 9.17248510227432, "BASILIXIMAB": 47.65441980889223, "BORTEZOMIB": 24.95663672358785, "BUDESONIDE": 4.360581559156878, "BUSILVEX": 27.77254114733388, "BUSULFAN": 159.62287621601405, "CARMUSTINE": 42.78955912100677, "CELLCEPT": 9.14950864387576, "CICLOSPORIN": 39.31315671690326, "CIDOFOVIR": 66.90277757766741, "CYTARABINE": 9.58301553449448, "DARATUMUMAB": 43.90331700365943, "DARZALEX": 4.630246963499437, "DEXAMETHASONE": 5.005234043528828, "DOXORUBICIN": 8.609450625438626, "GANCICLOVIR": 86.31765211281565, "JAKAVI": 3.0957088155735946, "MABCAMPATH": 77.28949380753357, "MELPHALAN": 47.8561605807521, "METHOTREXATE": 4.533693167267168, "MYCOPHENOLATE": 45.46914466321498, "RITUXIMAB": 2.3437168626612386, "RUXOLITINIB": 27.362096545156287, "SOLIRIS": 1.5892248380240168, "TACROLIMUS": 11.550805057576676, "THIOTEPA": 80.80282490665593, "TOFACITINIB": 67.43635724112387, "YESCARTA": 8.17698841467584}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/223.json
index 6e0f16a5f4a..39513ae45ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/223.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/223.json
@@ -1 +1 @@
-{"JANUMET": 7.760835061608442, "KEYTRUDA": 37.40681010923286, "OPDIVO": 24.177262636318197, "SUTENT": 1.084066964668018, "YERVOY": 21.74454274747636, "null": 1.008603572233704}
\ No newline at end of file
+{"AZACITIDINE": 316.805896993179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2230.json
index 52e83bc06f3..2db28de2e29 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2230.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2230.json
@@ -1 +1 @@
-{"ABACAVIR": 27.96341927510422, "MYCOPHENOLATE": 97.57945056011022}
\ No newline at end of file
+{"COMIRNATY": 0.1038340476450598, "ELIQUIS": 18.27697164491893, "MEPOLIZUMAB": 14.54909453948945, "OPSUMIT": 11.327414896630604, "SPIKEVAX": 0.3966295730078474, "TRACLEER": 14.403070509007652, "null": 1.0895171686722738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2231.json
index fe594a30f9c..ba5cb6b1f91 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2231.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2231.json
@@ -1 +1 @@
-{"CELLCEPT": 82.38600561826152, "GANCICLOVIR": 473.6931449373272}
\ No newline at end of file
+{"APIXABAN": 13.257791101702876, "COMIRNATY": 0.1849283245384222, "ELIQUIS": 5.49638656125288, "SPIRONOLACTONE": 112.57641288607954, "null": 0.8383225566659135}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2232.json
index 2cde51e8800..5f6145c9f46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2232.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2232.json
@@ -1 +1 @@
-{"CICLOSPORIN": 37.5374669093521}
\ No newline at end of file
+{"ARAVA": 1.114691562909403, "CLOPIDOGREL": 15.272256681450065, "COMIRNATY": 0.1704540841310443, "SPIKEVAX": 0.2710026705775016, "null": 1.3682501477670563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2233.json
index a399d023196..8ad8453feec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2233.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2233.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 9.3274580030513, "BASILIXIMAB": 38.7675211700053, "BUSULFAN": 59.35296027131064, "CELLCEPT": 87.83746432207568, "CICLOSPORIN": 27.329066846936666, "GANCICLOVIR": 14.490029374334371, "METHOTREXATE": 7.637652729705631, "MYCOPHENOLATE": 13.55302129206948}
\ No newline at end of file
+{"ABILIFY": 1.058866600825762, "ACTRAPID": 0.9686170011565364, "AERIUS": 0.5720467442345798, "AFINITOR": 0.2163343015963132, "AIMOVIG": 0.0991257910464702, "ALEMTUZUMAB": 0.334401425139763, "ALIMTA": 0.6002546032435294, "ALISKIREN": 0.4995068208804065, "ALL": 1.6033294457407297, "AMBRISENTAN": 2.0899313990081123, "AMIKACIN": 1.1544034037898736, "AMINOSALICYLIC": 0.5211035649867471, "ANGIOX": 12.874130494253755, "ANORO": 0.3515008450015544, "APIDRA": 0.1731010245029586, "APIXABAN": 0.0756574436009923, "APROVEL": 0.9787024005068792, "ARANESP": 0.2629158875027802, "ARAVA": 0.0248338757168627, "ARIPIPRAZOLE": 1.1033471735727047, "ARIXTRA": 2.228897879388682, "ASPARAGINASE": 0.551278298943536, "ATRIPLA": 0.0110743586436495, "AUBAGIO": 0.190048267973021, "AVANDAMET": 5.140590329875609, "AVANDIA": 6.976068509320149, "AVASTIN": 0.8073392167433654, "AZACITIDINE": 1.2264443846149569, "AZATHIOPRINE": 0.1718902414717792, "BARICITINIB": 16.209540481332596, "BASILIXIMAB": 0.8574767013325914, "BEDAQUILINE": 1.461553998051587, "BELIMUMAB": 1.4329396618455812, "BENLYSTA": 0.3813263274269873, "BENZODIAZEPINE": 7.560098872954715, "BIKTARVY": 0.4172649239206701, "BORTEZOMIB": 0.9288304095710236, "BRIDION": 23.451546517633684, "BRILIQUE": 3.004940514156303, "BUDESONIDE": 0.209347400709087, "BUPIVACAINE": 4.185911641120245, "BUPRENORPHINE": 1.5430647069253014, "BUSULFAN": 0.4307632794605343, "BYDUREON": 0.4251943605312603, "BYETTA": 0.4196949642270666, "CAELYX": 0.4000057966802978, "CANCIDAS": 0.6704146131374047, "CAPECITABINE": 0.4966660864942608, "CARFILZOMIB": 0.6036134965611485, "CARIPRAZINE": 5.445184486571681, "CASPOFUNGIN": 1.3404023646454442, "CELECOXIB": 0.7910328297681838, "CELLCEPT": 0.635649773096962, "CHAMPIX": 0.553413024650184, "CICLOSPORIN": 0.4717774180892727, "CIMZIA": 0.074445633999633, "CLOPIDOGREL": 1.0451779048026515, "COAPROVEL": 0.5458983616616335, "COMBIVIR": 0.6832933675487716, "COMIRNATY": 0.238091115936001, "COMTAN": 0.9098333558013068, "COSENTYX": 0.1363409478555419, "CRIXIVAN": 0.5700783839333974, "CUBICIN": 1.6248209388348642, "CYMBALTA": 0.3904518419431402, "CYTARABINE": 0.8064287994069284, "DAKLINZA": 1.0765523974604978, "DARZALEX": 0.5447961261946949, "DELAMANID": 0.9729543608807236, "DEXAMETHASONE": 1.6331099002406484, "DEXDOR": 29.16191884508936, "DEXMEDETOMIDINE": 14.205922206338156, "DOCETAXEL": 0.220976375212778, "DOXORUBICIN": 1.0646877273455368, "DULOXETINE": 3.1258604645990458, "ELIQUIS": 0.935967484484988, "EMEND": 0.7382264893743691, "EMPAGLIFLOZIN": 1.7397445667396965, "ENBREL": 0.0694663462932892, "ENOXAPARIN": 1.2211030965009042, "ENTRESTO": 1.5541797279300815, "ENTYVIO": 0.155230840472398, "EPCLUSA": 0.920374442109814, "ERBITUX": 1.0540785201304852, "ESBRIET": 0.8493627376512026, "ESOMEPRAZOLE": 0.5052676191057519, "EVENITY": 0.4462974500687385, "EVISTA": 0.3035695179685684, "EXFORGE": 1.403997719474365, "EXJADE": 0.7877114347557811, "EXVIERA": 1.188127578081282, "EYLEA": 0.2112887582042069, "FAMPYRA": 0.6013460055947533, "FASENRA": 0.3387207204105172, "FASLODEX": 0.3671720041714975, "FEBUXOSTAT": 1.3298865206912365, "FENTANYL": 8.810495495311976, "FESOTERODINE": 14.19815081421435, "FILGRASTIM": 0.98186208622675, "FIRDAPSE": 0.6316942057923063, "FORSTEO": 0.6941678439604897, "FORXIGA": 0.4204003441055854, "FULVESTRANT": 0.6564484485289156, "GALVUS": 0.8487282699311589, "GANCICLOVIR": 1.7590121425982712, "GARDASIL": 0.1062191224322013, "GLIBENCLAMIDE": 2.453516639566473, "GLIVEC": 0.6121876559835067, "GLUCAGON": 22.185338824506704, "HARVONI": 0.6592956252208775, "HERCEPTIN": 0.421768800921304, "HIZENTRA": 0.4857478856298621, "HUMALOG": 0.5398283349513149, "HUMAN": 0.8409581007757704, "HUMIRA": 0.0999800676210231, "HYDROCORTISONE": 0.8624080368486556, "IBRANCE": 0.1596575289248707, "IBUPROFEN": 2.552187720480773, "ICLUSIG": 0.6085503743479782, "INCIVO": 0.3807974729248115, "INCRUSE": 0.964852333999382, "INFANRIX": 0.6629239066471857, "INLYTA": 0.1905665027238826, "INSULIN": 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"MIRCERA": 4.069832332566697, "MULTAQ": 2.258779567346792, "NAGLAZYME": 3.0666939014187347, "NALOXONE": 8.769090004829028, "NEULASTA": 0.4354506654009936, "NEXAVAR": 0.2308271002791752, "NOT": 4.020238732148068, "NOVORAPID": 0.1889856343856788, "NOVOSEVEN": 4.81014164974593, "NOXAFIL": 2.0398123914579114, "NPLATE": 1.745270910114413, "NUCALA": 0.357843309859718, "OFEV": 0.3823708128576245, "OLANZAPINE": 2.6049671864775124, "OMALIZUMAB": 0.6476400099986716, "ONGLYZA": 1.086622450683545, "OPDIVO": 0.3247438273153857, "OPSUMIT": 1.8890613161566856, "OPTIMARK": 0.3211059948741183, "OXYBUTYNIN": 1.4460484995833194, "PACLITAXEL": 0.6506337410953574, "PALIPERIDONE": 3.400350905701708, "PANTOPRAZOLE": 0.7860053777878224, "PEGASYS": 0.3648841660512957, "PEGINTRON": 0.3135300911521805, "PEMBROLIZUMAB": 0.29559153991628, "PLAVIX": 1.0747110791233128, "POSACONAZOLE": 1.1361345614345797, "PRADAXA": 2.631377587274264, "PRAXBIND": 4.893297045316147, "PREGABALIN": 5.001921069653288, "PREVENAR": 0.6047145343823584, "PRIALT": 6.58525693726546, "PRIVIGEN": 0.2687087880898078, "PROCORALAN": 6.443030353386238, "PROPRANOLOL": 8.952217778550065, "RANEXA": 1.4397739535015692, "RANOLAZINE": 3.9003529525993774, "RAPAMUNE": 0.5950466547687318, "RAPILYSIN": 12.686668756011954, "RAPISCAN": 27.998892804404505, "RASILEZ": 1.3842156937712922, "REBETOL": 0.7852451954095621, "REGADENOSON": 24.92043848809712, "REMDESIVIR": 9.56632911337149, "REVATIO": 2.9202887497744503, "REVLIMID": 0.6530104447025405, "RIBAVIRIN": 0.4627052704266441, "RINVOQ": 0.3234396874088742, "RISPERIDONE": 0.5660350764302352, "RITUXIMAB": 0.4964013377207242, "RIVAROXABAN": 1.526244526494871, "ROACTEMRA": 0.5257616681837314, "ROSIGLITAZONE": 4.991640345160891, "SAXENDA": 0.2100106924728886, "SHINGRIX": 0.1052822276841911, "SILDENAFIL": 3.116359758503636, "SIMPONI": 0.2711006713845033, "SODIUM": 5.691845298571863, "SOLIRIS": 1.7544258615077413, "SOVALDI": 1.0951323378525075, "SPIKEVAX": 0.2747043978499359, "SPINRAZA": 4.748934470221276, "SPIRONOLACTONE": 1.029503520756795, "SPRYCEL": 0.5003555639564724, "STALEVO": 0.7381398581022856, "STELARA": 0.3753369924428264, "STRIBILD": 0.0704932365934072, "SUBOXONE": 0.6964499008071053, "SUFENTANIL": 12.445443274570842, "SUGAMMADEX": 16.758361704744704, "SUTENT": 0.6452178672290889, "SYNAGIS": 2.315989397374406, "TAGRISSO": 0.8233091046296256, "TAMIFLU": 1.1109899250115232, "TASIGNA": 0.7100510022458231, "TELMISARTAN": 1.0921512753854032, "TESTOSTERONE": 0.862452148197221, "THALIDOMIDE": 1.1270094503863024, "TICAGRELOR": 1.9240145208419843, "TOBRAMYCIN": 1.4644454323033549, "TOCILIZUMAB": 1.0337475051927305, "TOZINAMERAN": 0.345938215635269, "TRACLEER": 3.413382068506249, "TRAZODONE": 31.970430033842455, "TRELEGY": 0.6849039753588844, "TREMFYA": 0.2615711303275813, "TRULICITY": 0.3314965848035676, "UNSPECIFIED": 19.10424750165365, "VALSARTAN": 1.4161958156533614, "VAXZEVRIA": 0.1554975331347639, "VELTASSA": 1.2701395663436976, "VFEND": 1.3332851481601788, "VIAGRA": 1.4359809181431735, "VICTOZA": 0.5268339208947053, "VIMPAT": 1.761976393164037, "VORICONAZOLE": 0.7071690314144283, "VOTRIENT": 0.1971587509816207, "XALKORI": 0.6903174221726825, "XARELTO": 0.2991755012045635, "XELJANZ": 0.2315958890171711, "XELODA": 1.0083040764976132, "XOLAIR": 0.6627039143821063, "XTANDI": 0.5610871143658386, "YERVOY": 0.492535634856785, "YESCARTA": 0.5774024700353727, "ZOSTAVAX": 0.1933441861617842, "ZYPADHERA": 0.3470556023823865, "ZYPREXA": 1.5670206666523518, "null": 2.655866007396209}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2234.json
index bd5d30e4368..e606bde9f72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2234.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2234.json
@@ -1 +1 @@
-{"BUSULFAN": 1227.9181626583058}
\ No newline at end of file
+{"null": 4.150517480594683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2235.json
index a624c7f7ea0..70c89581560 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2235.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2235.json
@@ -1 +1 @@
-{"ABATACEPT": 1.4301977318973758, "ALEMTUZUMAB": 70.69391237765147, "ASPARAGINASE": 42.33850662187424, "AZATHIOPRINE": 11.486706916890975, "BASILIXIMAB": 110.03705505900382, "BUDESONIDE": 1.2739164474526696, "BUSULFAN": 146.91842158669846, "CELLCEPT": 48.288812454449406, "CICLOSPORIN": 22.08102360659077, "CYTARABINE": 4.87524639858387, "GANCICLOVIR": 174.12577136506067, "HUMAN": 7.990011173139972, "INFLIXIMAB": 11.528473410068775, "MELPHALAN": 34.398773285034835, "METHOTREXATE": 4.04419748024166, "MYCOPHENOLATE": 67.58303911517848, "RITUXIMAB": 5.029090110871184, "SOLIRIS": 4.228851188833217, "TACROLIMUS": 20.03520013050089}
\ No newline at end of file
+{"AVANDIA": 123.18733186227288, "SPIKEVAX": 0.6583957099680804, "null": 0.6895882792690293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2236.json
index db1c7976fda..9170005fe04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2236.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2236.json
@@ -1 +1 @@
-{"AFINITOR": 1.040639234735106, "ALEMTUZUMAB": 5.205078316545678, "ALIMTA": 2.4674156962593914, "AMIKACIN": 3.585680219840901, "ASPARAGINASE": 5.341708217348028, "AVASTIN": 2.9195586738534662, "AXICABTAGENE": 23.79181085440169, "AZACITIDINE": 60.88229519497963, "AZATHIOPRINE": 2.1262446092660165, "BASILIXIMAB": 6.106655348430063, "BEVACIZUMAB": 1.7928673343016763, "BLINATUMOMAB": 29.00294805645041, "BORTEZOMIB": 18.87253410947666, "BOSULIF": 8.93442349340159, "BOSUTINIB": 24.3944787232268, "BUSULFAN": 5.670162834400365, "CAPECITABINE": 5.324886618842485, "CARFILZOMIB": 23.260600354078083, "CARMUSTINE": 24.80399215363396, "CELLCEPT": 2.9785997732511453, "CICLOSPORIN": 2.3479491057831146, "CLADRIBINE": 6.426857346856362, "CYTARABINE": 16.663481171374332, "DARZALEX": 10.739210544069191, "DASATINIB": 9.56926523026553, "DEXAMETHASONE": 9.822803176679155, "DOCETAXEL": 6.39954381855615, "DOXORUBICIN": 22.52108065990787, "EXJADE": 1.5707985517326253, "FASLODEX": 2.9905385837558547, "FILGRASTIM": 13.273573849627804, "FULVESTRANT": 4.135166399868111, "GANCICLOVIR": 15.098563552720655, "GAZYVARO": 9.674967489012186, "GLIVEC": 5.404369366278683, "IBRANCE": 8.640406334935028, "IBRUTINIB": 16.70377268500021, "ICLUSIG": 21.968000783436064, "IMATINIB": 26.45298438250614, "IRINOTECAN": 2.5352545830792703, "JAKAVI": 12.707895161227489, "KEYTRUDA": 2.2119957267416464, "KYMRIAH": 29.985330289574986, "KYPROLIS": 14.919717924560818, "LEFLUNOMIDE": 4.381435759784064, "LENALIDOMIDE": 13.47495918984489, "LONSURF": 13.812080230516608, "LYNPARZA": 1.8068117616473691, "MABTHERA": 12.448662665677974, "MERCAPTOPURINE": 7.559227504848666, "METHOTREXATE": 1.3317329959163775, "NEXAVAR": 1.181357775487986, "NILOTINIB": 20.32585334241448, "NINLARO": 4.040620449673044, "OPDIVO": 1.0643791103432194, "PACLITAXEL": 7.43640178720185, "PEGASYS": 1.0352987126585118, "PEGINTERFERON": 4.204027216059306, "PEGINTRON": 1.5070681991440935, "PEMBROLIZUMAB": 2.721372608881852, "PEMETREXED": 8.661589289839752, "POMALIDOMIDE": 17.352421602742933, "REVLIMID": 5.002848039361536, "RIBAVIRIN": 1.702673413075312, "RITUXIMAB": 9.10827779289287, "RUBRACA": 2.256026468290968, "RUXOLITINIB": 25.42609783087823, "RYDAPT": 26.661558419767022, "SOLIRIS": 1.4995996780086749, "SPRYCEL": 14.195674988659032, "SUTENT": 1.373606004785727, "TASIGNA": 7.478090340930419, "TEGAFUR": 19.408090829709096, "TEMODAL": 6.196162914729093, "TEMOZOLOMIDE": 4.797980290171688, "THALIDOMIDE": 3.3614996845067195, "TOPOTECAN": 12.53149195204519, "TRODELVY": 3.517697347102612, "VENCLYXTO": 28.77747316386831, "VENETOCLAX": 62.149635967532646, "VYXEOS": 33.687354447347786, "XELODA": 3.4056755886808654, "XOFIGO": 3.0320461890814507, "YESCARTA": 31.33116623690948}
\ No newline at end of file
+{"COMIRNATY": 0.5790398312289434, "null": 1.2351887965815302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2237.json
index 4adfb229540..0a5ade348ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2237.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2237.json
@@ -1 +1 @@
-{"COMIRNATY": 1.403930532756912}
\ No newline at end of file
+{"ADCIRCA": 466.59213295219536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2238.json
index 84e640e77d6..70d792829a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2238.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2238.json
@@ -1 +1 @@
-{"null": 1.017980813242261}
\ No newline at end of file
+{"null": 1.4452701740241307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2239.json
index a453d0e5c39..19c4db28b4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2239.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2239.json
@@ -1 +1 @@
-{"COMIRNATY": 1.947862684820601}
\ No newline at end of file
+{"AVANDIA": 13.037123620844204, "CLOPIDOGREL": 6.362345534430719, "COMIRNATY": 0.8507479777195033, "FENTANYL": 43.98452915973464, "SPIKEVAX": 0.4191333777977971, "TESTOSTERONE": 98.66579407767033, "VAXZEVRIA": 0.2896986469010195, "null": 0.4102630638517188}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/224.json
index 9043f093d8a..2fa9dd4c837 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/224.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/224.json
@@ -1 +1 @@
-{"null": 1.760924754470565}
\ No newline at end of file
+{"LEVOFLOXACIN": 19.929477759064387, "null": 0.2174404675719465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2240.json
index 592cb1cf87e..a32ac980982 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2240.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2240.json
@@ -1 +1 @@
-{"null": 1.0369890049532702}
\ No newline at end of file
+{"CLOPIDOGREL": 0.9481088400788557, "COMIRNATY": 4.862487694500337, "CYMBALTA": 0.2709583430910287, "FORSTEO": 1.407173473022816, "JARDIANCE": 0.6210790040131491, "SPIKEVAX": 3.550092927489277, "TOZINAMERAN": 0.7089792014879153, "VAXZEVRIA": 0.621849215368006, "null": 0.4540556466143147}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2241.json
index b6efd5a4264..c735c582670 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2241.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2241.json
@@ -1 +1 @@
-{"ASPARAGINASE": 43.55443140879772, "DOCETAXEL": 55.22500378149138, "null": 3.992785387049844}
\ No newline at end of file
+{"ABATACEPT": 0.0733639038913424, "ABILIFY": 0.5929659871957443, "ACLIDINIUM": 0.8401028542714741, "ACTRAPID": 2.652406787140249, "ADCIRCA": 0.6824775712477895, "ADEMPAS": 0.7590005646271597, "AFINITOR": 0.2906227778573806, "AIMOVIG": 0.6387664356528299, "ALIMTA": 0.3315410103481192, "AMBRISENTAN": 2.335791926300617, "ANAKINRA": 0.7487074737387317, "ANORO": 1.497350620049602, "APIDRA": 1.631503077557843, "APIXABAN": 11.149650008815064, "APROVEL": 0.8059306218942687, "ARANESP": 0.8556025220554753, "ARAVA": 0.2258951885986979, "ARIPIPRAZOLE": 0.3436381673860575, "ASPARAGINASE": 0.4530709906526278, "ATRIPLA": 0.0488773871713247, "AUBAGIO": 0.4551060732506691, "AVAMYS": 0.3741502537012648, "AVANDAMET": 28.943638573777896, "AVANDIA": 27.684924740229363, "AVASTIN": 0.3012325950445316, "AZACITIDINE": 1.7377584240066537, "AZATHIOPRINE": 0.3395688943342193, "BENLYSTA": 0.8150242099416757, "BETMIGA": 1.3130037138913575, "BEXTRA": 4.409715635119716, "BIKTARVY": 0.4195758488965772, "BOSULIF": 3.738463972650453, "BRAFTOVI": 0.8856097196261958, "BRILIQUE": 0.2309717978110823, "BUDESONIDE": 0.5281338395886331, "BUPIVACAINE": 0.9319283132153042, "BUPRENORPHINE": 0.985626388548826, "BYDUREON": 1.119710501692776, "BYETTA": 0.9506207616272796, "CABOMETYX": 0.2333952043281904, "CAELYX": 0.8251663975350747, "CAPECITABINE": 0.2653655237142237, "CARFILZOMIB": 0.980028380628697, "CELECOXIB": 0.7564495873772197, "CELLCEPT": 0.4310621629742449, "CHAMPIX": 0.7204148164564196, "CHOLESTAGEL": 14.166109860590428, "CIALIS": 7.922941329325782, "CICLOSPORIN": 0.3825728671400393, "CIMZIA": 0.4669208480356319, "CLOPIDOGREL": 1.0735097206804824, "COMIRNATY": 0.224352431130988, "COSENTYX": 0.5955275313887527, "COTELLIC": 1.308871394333995, "CYMBALTA": 0.440130852798445, "CYTARABINE": 0.2305805992295721, "DARZALEX": 0.7462922815878424, "DEXAMETHASONE": 0.4043161409577107, "DOXORUBICIN": 0.4997113339925803, "DULAGLUTIDE": 2.429750586831433, "DULOXETINE": 1.0887213104088804, "ELIQUIS": 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0.4042716300955172, "ICLUSIG": 2.729452683090871, "INCRUSE": 2.263635782204124, "INLYTA": 1.6101013427521922, "INSULIN": 2.198844182532408, "IRBESARTAN": 0.8142988497965924, "ISENTRESS": 1.300758769223529, "JAKAVI": 0.7272842442454771, "JANUMET": 1.5164992656588716, "JANUVIA": 1.4981000098577733, "JARDIANCE": 1.5095461377851231, "KEPPRA": 0.2327116055601583, "KEYTRUDA": 0.4246477193714693, "KISQALI": 0.4732694045383381, "KYPROLIS": 4.42402150238164, "LANTUS": 4.061948201118551, "LATUDA": 0.5666252228339572, "LEFLUNOMIDE": 0.6002159550794195, "LEVEMIR": 1.341583024763037, "LEVOFLOXACIN": 0.2552101704977449, "LYRICA": 1.080516562818893, "MEKINIST": 1.0494457350587427, "MELATONIN": 0.9246469375619052, "MEPOLIZUMAB": 0.4340624014574534, "METHOTREXATE": 0.6930908981355098, "MICARDIS": 0.8608532121033071, "MIMPARA": 1.393513899374033, "MIRCERA": 1.1887526366553738, "MULTAQ": 0.8461670983023777, "NAGLAZYME": 2.6926295172548267, "NEULASTA": 0.8316616099359301, "NEXAVAR": 0.1857724433314492, 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"XALKORI": 0.7155887333519316, "XARELTO": 0.475205456119556, "XELJANZ": 2.1057201034271458, "XELODA": 0.7764327378717937, "XOFIGO": 0.8667922794259899, "XOLAIR": 1.1917181682423277, "XTANDI": 1.729548566294439, "ZELBORAF": 0.7724037207464894, "ZOSTAVAX": 2.404992183175648, "ZYPREXA": 0.9280052875917102, "null": 1.276946521446272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2242.json
index 72b66110290..cacc594a502 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2242.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2242.json
@@ -1 +1 @@
-{"null": 3.8654239520323976}
\ No newline at end of file
+{"ARIPIPRAZOLE": 14.908669678459162, "AXITINIB": 17.493476301350345, "BRAFTOVI": 10.987264599353784, "CLOPIDOGREL": 1.672884809425344, "COMIRNATY": 0.4441007433974652, "CYTARABINE": 3.820968920288356, "DEXAMETHASONE": 3.481771537068132, "DOCETAXEL": 4.618435820008648, "ELIQUIS": 1.0040639898056958, "ENTRESTO": 23.83435988466822, "FENTANYL": 2.402239351991495, "HERCEPTIN": 74.86613243387622, "INLYTA": 5.371599943587871, "KEYTRUDA": 4.289507000475235, "KYPROLIS": 17.464612573566626, "MEKINIST": 4.443951704125717, "OLANZAPINE": 1.5216392031296984, "PACLITAXEL": 42.873290971667046, "SPIKEVAX": 0.2754925618319966, "STIVARGA": 3.819022199562944, "SUTENT": 0.6985422321788614, "TAGRISSO": 12.327542922884517, "TOZINAMERAN": 0.3925031132558252, "TRASTUZUMAB": 388.6841683303037, "VOTRIENT": 3.0123516808971083, "null": 0.5086404248178134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2243.json
index 55bbfbceaed..294d1dba05c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2243.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2243.json
@@ -1 +1 @@
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\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2244.json
index daf15e74693..e8b2a95f4a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2244.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2244.json
@@ -1 +1 @@
-{"GARDASIL": 13.313539013643542, "ROTATEQ": 105.22214826210984}
\ No newline at end of file
+{"AFINITOR": 0.8466037214555371, "BARACLUDE": 13.218519776758953, "BEDAQUILINE": 4.330301833171965, "BORTEZOMIB": 4.202158128334568, "BUMETANIDE": 48.36291223594856, "BUSULFAN": 2.079989746461655, "CARFILZOMIB": 7.419773910700125, "CLOPIDOGREL": 3.0453167882245884, "COMIRNATY": 0.5360828141006236, "CYMBALTA": 0.9216992292546028, "DARZALEX": 2.804596034246313, "DEXAMETHASONE": 0.9211525403416564, "ELIQUIS": 2.723996810107008, "ENTRESTO": 13.252002112572542, "EVENITY": 3.824127992436815, "FENTANYL": 1.4373589042520831, "FORSTEO": 0.7547697785161653, "FORXIGA": 2.1386307975277274, "HERCEPTIN": 7.144756622736439, "ICLUSIG": 5.71769684477199, "INLYTA": 1.6329041423907409, "JARDIANCE": 1.0133629621080416, "KEYTRUDA": 2.6856154176545903, "KYPROLIS": 30.085286773686374, "LEVOFLOXACIN": 0.8611864383157873, "NEXAVAR": 1.762241597648767, "OLANZAPINE": 1.279960960011563, "ONGLYZA": 18.328812141772666, "OPSUMIT": 3.358787067025721, "PEGINTRON": 0.9654399226311736, "PLAVIX": 1.511726868680168, "SIMPONI": 1.470783252566776, "SPIKEVAX": 0.3519022450134904, "SPIRONOLACTONE": 7.207733421182305, "SPRYCEL": 1.6497489897901083, "SUTENT": 0.7067045873773654, "TAGRISSO": 5.251452961857661, "TAMIFLU": 7.800588409694852, "TRACLEER": 6.1118079827408085, "VAXZEVRIA": 0.1179660258577106, "VOTRIENT": 2.144540732028472, "XTANDI": 1.1955778159475925, "ZYPREXA": 0.8567905832659539, "null": 1.045794810168855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2245.json
index 70eb785549d..08ff38e60b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2245.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2245.json
@@ -1 +1 @@
-{"null": 4.985036164393428}
\ No newline at end of file
+{"ALISKIREN": 12.397215735798724, "APIXABAN": 3.352653791939769, "AVANDIA": 3.4220726169463966, "BEDAQUILINE": 7.646568244383743, "BLINDED": 114.53269885402406, "BUMETANIDE": 73.11199206741138, "CICLOSPORIN": 1.1002458315981376, "CLOPIDOGREL": 3.4794801650891003, "COMIRNATY": 0.2585539158581997, "DAPAGLIFLOZIN": 28.612698340317383, "ELIQUIS": 3.016411088138651, "EMPAGLIFLOZIN": 9.437037854556277, "ENTRESTO": 37.40315701387538, "FORXIGA": 7.398541628674737, "IRBESARTAN": 7.355031865143697, "JARDIANCE": 1.484965996275754, "KYPROLIS": 8.164183437982837, "LANTUS": 0.7841888705187469, "MULTAQ": 10.43157828006213, "OPSUMIT": 1.2665461650985574, "PANTOPRAZOLE": 8.362065254725474, "REVATIO": 7.801808409739831, "SAMSCA": 94.06503655237576, "SILDENAFIL": 6.240687948742012, "SPIKEVAX": 0.1329994689650222, "SPIRONOLACTONE": 15.211152678003312, "TAGRISSO": 3.822153430360925, "TRACLEER": 4.221873232979084, "VALSARTAN": 66.99707054268391, "null": 1.2467113817299145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2246.json
index 9f2bd9cb16c..f7f77187224 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2246.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2246.json
@@ -1 +1 @@
-{"COMBIVIR": 87.95008923313456, "null": 1.449189824942389}
\ No newline at end of file
+{"ABACAVIR": 0.1116688163071527, "ABATACEPT": 0.0930731867842605, "ABILIFY": 0.2197634335666407, "ACTOS": 9.663846120743306, "ADALIMUMAB": 0.0555191715455239, "ADCIRCA": 2.287401293495339, "ADEMPAS": 1.6972327667406302, "AFINITOR": 0.7539889374994185, "AIMOVIG": 0.3292415985307788, "ALEMTUZUMAB": 0.399469348014973, "ALENDRONATE": 18.63724693547656, "ALIMTA": 0.387543798233113, "AMBRISENTAN": 3.314884161874975, "ANORO": 1.0413783792032605, "APIDRA": 0.5976144484846457, "APIXABAN": 2.534364416670424, "ARANESP": 1.0672515698869964, "ARAVA": 0.4464330300139542, "AUBAGIO": 0.2270340608931325, "AVANDAMET": 104.45365419160404, "AVANDIA": 144.43890921627548, "AVASTIN": 0.938135010788448, "BEDAQUILINE": 0.3394030404872363, "BENLYSTA": 0.3210857399481242, "BEVACIZUMAB": 0.3398704996601327, "BLINDED": 18.922203568784237, "BORTEZOMIB": 0.5236504714208677, "BOSENTAN": 2.5057879444505504, "BOSULIF": 3.9613967168217856, "BRILIQUE": 0.3922492334144877, "BUDESONIDE": 0.3959720818101467, "BUMETANIDE": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2247.json
index 7f14fdbdf11..09c222057a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2247.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2247.json
@@ -1 +1 @@
-{"null": 1.507238952741868}
\ No newline at end of file
+{"OPSUMIT": 42.56940276906448, "null": 1.7316313330309665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2248.json
index a440158ea3d..28e55a01040 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2248.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2248.json
@@ -1 +1 @@
-{"HUMALOG": 51.44004911211495, "LANTUS": 18.7737151219152}
\ No newline at end of file
+{"CLOPIDOGREL": 2.552840815928164, "COMIRNATY": 1.7988567719312616, "ELIQUIS": 4.02092546271035, "PLAVIX": 4.202850152388321, "SPIKEVAX": 0.9545110435646968, "VAXZEVRIA": 0.5471997552109066, "null": 0.992038527377766}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2249.json
index 3b96a04ecbe..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2249.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2249.json
@@ -1 +1 @@
-{"BRINTELLIX": 6.370097728739999, "CHAMPIX": 6.5248955498155246, "KEPPRA": 4.345350039322753, "LANTUS": 1.9408986102892245, "null": 1.6039471471820594}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/225.json
index b0aaf61503f..0dab61bdfbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/225.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/225.json
@@ -1 +1 @@
-{"ENOXAPARIN": 77.96876009259375, "VAXZEVRIA": 1.1209699123003525, "null": 1.483916114225806}
\ No newline at end of file
+{"ABACAVIR": 0.887282205972225, "ACTOS": 3.4883791970158367, "ADENURIC": 2.359219546992561, "AFINITOR": 0.2745498927597853, "AIMOVIG": 0.6018260791978541, "ALIMTA": 0.7252502648726484, "ANGIOX": 9.35550442101695, "APIXABAN": 0.440979379162697, "ARANESP": 0.7160588873872767, "ARAVA": 0.0841451419099779, "ATAZANAVIR": 1.150726085688363, "AUBAGIO": 0.2181356484505839, "AVANDAMET": 23.618047233122965, "AVANDIA": 21.50512379412397, "AVASTIN": 1.7483942395065135, "BARACLUDE": 1.8709262706272625, "BEDAQUILINE": 0.7347496320306244, "BEVACIZUMAB": 0.735901105521557, "BIKTARVY": 0.9234548186923291, "BLINDED": 27.47800415566948, "BORTEZOMIB": 1.00121130735562, "BRAFTOVI": 0.7510758048506607, "BRIDION": 1.2922527765412597, "BRILIQUE": 9.088312908134576, "BRINTELLIX": 0.2872984529105886, "BUPRENORPHINE": 0.3867470469089364, "BYETTA": 1.0010735324803983, "CABOMETYX": 0.8582582196284331, "CAPECITABINE": 1.2849446675460623, "CHAMPIX": 2.836886430456195, "CIALIS": 2.949585464929604, "CICLOSPORIN": 0.2417892382721964, "CIMZIA": 0.2870143674117996, "CLOPIDOGREL": 7.857839339693579, "COMBIVIR": 0.5907353613465268, "COMIRNATY": 0.6699805253181965, "COSENTYX": 0.5834875683479347, "CYMBALTA": 0.154251553014386, "DAPAGLIFLOZIN": 8.230450875353094, "DARZALEX": 0.937697650400651, "DASATINIB": 4.2402718731439375, "DEXAMETHASONE": 0.465079978094882, "DOXORUBICIN": 1.9578716640861364, "EFIENT": 9.723389847598872, "ELIQUIS": 1.450414774559098, "EMPAGLIFLOZIN": 1.3064174934302732, "ENBREL": 0.2667570388634287, "ENOXAPARIN": 1.216672829003033, "ENTRESTO": 1.563030167607308, "ENZALUTAMIDE": 2.111585689205826, "ESBRIET": 0.8247978506462651, "EVENITY": 7.325563270362159, "EVISTA": 2.232325945134727, "EXFORGE": 0.4486787195362385, "EXJADE": 0.2710704174572416, "EXVIERA": 1.8276693906964023, "EYLEA": 2.978057786102086, "FASENRA": 0.6089637560935824, "FEBUXOSTAT": 21.613647337196824, "FENTANYL": 0.5207326379430574, "FORSTEO": 0.5923755006694498, "FORXIGA": 1.3913629069526323, "GLYCOPYRRONIUM": 4.219261580589798, "HARVONI": 1.5360139532089792, "HEMLIBRA": 3.300221122539162, "HUMALOG": 0.5207432982316206, "HUMAN": 1.6387477714304337, "HUMIRA": 2.0782178330116072, "IBUPROFEN": 0.5750565786670775, "ICLUSIG": 7.349228006838453, "INCIVO": 0.634959649004406, "INLYTA": 1.2816184495617535, "INSULIN": 0.5216169708910489, "INTEGRILIN": 3.835703028270673, "JAKAVI": 0.7090978638357469, "JANUMET": 0.3635766252573128, "JANUVIA": 0.8025521249350787, "JARDIANCE": 2.2610317686903767, "KALETRA": 0.8229314564623906, "KEYTRUDA": 0.5603069420744915, "KYPROLIS": 3.221901239672089, "LANTUS": 0.4838504585692347, "LENVIMA": 1.8275989815306384, "LIXIANA": 0.804887053734454, "MEPOLIZUMAB": 0.7025998313380716, "METFORMIN": 1.90772852411822, "METHOTREXATE": 0.2296944584519923, "MICARDIS": 1.2845429803199364, "MODERNA": 0.5380125346243768, "NEXAVAR": 3.304658781788562, "NILOTINIB": 8.669747674408413, "NORVIR": 1.960364149307695, "NOT": 1.1155417090199211, "NOVOSEVEN": 9.381868743964557, "NPLATE": 3.7500235484250375, "NUCALA": 0.4780169332164747, "OFEV": 2.8617991978765023, "OLANZAPINE": 0.5811433699322663, "ONGLYZA": 8.323788079628846, "OPSUMIT": 0.3299241132728586, "PEGASYS": 0.3931013657627376, "PEGINTERFERON": 0.6638093614850809, "PEGINTRON": 0.8120019903357145, "PEMBROLIZUMAB": 0.4959689305651388, "PLAVIX": 5.323017518064351, "PRADAXA": 2.397096144436281, "PREGABALIN": 0.7051649857003363, "PRIVIGEN": 0.6211555558814555, "RELVAR": 1.302148311401014, "REMDESIVIR": 3.144398885199532, "REVATIO": 0.6856833289463563, "RINVOQ": 1.4881120449755918, "RITUXIMAB": 0.3453529550073594, "ROACTEMRA": 1.6216177608546682, "ROSIGLITAZONE": 10.607729548212124, "SILDENAFIL": 5.27220839707501, "SIMPONI": 0.7018223935784759, "SOLIRIS": 0.6910520276938028, "SPIKEVAX": 0.6612986820447915, "SPRYCEL": 0.9433466508073516, "STELARA": 1.318101879745611, "STIVARGA": 1.0099683777472122, "SUTENT": 0.5798508787797112, "TASIGNA": 6.658241906034445, "TESTOSTERONE": 17.576976517201253, "THALIDOMIDE": 2.51947590093894, "TICAGRELOR": 8.448810431637515, "TOZINAMERAN": 0.2805776159878012, "TRACLEER": 0.3671390025769178, "TREMFYA": 0.6764249548436677, "TRIUMEQ": 4.364114634545663, "TRULICITY": 0.4725471181530643, "TRUVADA": 0.0684524392957794, "VAXZEVRIA": 0.4738135391989832, "VIAGRA": 3.071445946813132, "VICTOZA": 0.6391518892723178, "VOTRIENT": 0.8701229555387393, "XARELTO": 0.958870708540462, "XELJANZ": 0.6945317115656034, "XOLAIR": 0.6680554273817745, "XTANDI": 0.4430932038858401, "ZOSTAVAX": 0.5429899330426398, "ZYPREXA": 0.4358420678060862, "null": 0.9821601051127616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2250.json
index 57a2e268d45..b18249d4145 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2250.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2250.json
@@ -1 +1 @@
-{"ACALABRUTINIB": 57.3306409342533, "ACETYLSALICYLIC": 38.75254920919572, "ADCIRCA": 1.6679256401212252, "AIMOVIG": 1.1305061451157326, "AMIKACIN": 20.19182224680455, "AMINOSALICYLIC": 1.1154387019989214, "AVAMYS": 1.047562771138354, "BEDAQUILINE": 2.002107846030778, "BIKTARVY": 1.5834696382861675, "BUMETANIDE": 3.171814098222176, "CIALIS": 2.872432561702933, "CIMZIA": 1.6873954574259755, "EXFORGE": 2.0503002588351293, "EXJADE": 4.731883978338439, "FASENRA": 1.3880689402183437, "HUMALOG": 1.5546915253302775, "HUMIRA": 1.0097086089847631, "IBRANCE": 2.920530624708003, "INTRONA": 2.540927256395358, "LAMIRA": 48.54162470990339, "LANTUS": 1.6006367850806569, "LEVEMIR": 1.0954875807638578, "NAGLAZYME": 1.5236128562382367, "NOT": 1.066677971371263, "PEGASYS": 2.204780301795479, "PEGINTRON": 2.2004023581835623, "RAPAMUNE": 1.1743936761939142, "REBETOL": 1.7530516508627203, "REVATIO": 4.578278852315695, "SHINGRIX": 1.861957329177129, "SILDENAFIL": 1.817134103326106, "SOVALDI": 1.4959224440777237, "TASIGNA": 1.2587741025569086, "THIOTEPA": 18.3052108148416, "TIVICAY": 2.841806514409853, "TOBRAMYCIN": 7.869634104270363, "TOVIAZ": 1.9511348800522543, "TOZINAMERAN": 2.3695526984571567, "TRULICITY": 1.1868155318946978, "VFEND": 1.9802630142143391, "VIAGRA": 10.85084725184446, "XELJANZ": 2.0885520602808274, "ZOSTAVAX": 9.557754320972135, "null": 1.2337878941191125}
\ No newline at end of file
+{"AIMOVIG": 0.8566747007728264, "AVANDIA": 1.4758720492012651, "BUDESONIDE": 1.051811705924124, "BYDUREON": 2.136243225275757, "COMIRNATY": 1.3389097827987342, "ELIQUIS": 2.19029393342861, "ENTRESTO": 0.8316948993790224, "IBRANCE": 0.4435290037123269, "MICARDIS": 1.866148540055834, "MULTAQ": 3.7966228865027967, "OCRELIZUMAB": 2.1716398788838114, "SPIKEVAX": 1.776341823747445, "SPRYCEL": 1.4544029043588331, "STELARA": 0.7690884108691289, "SUTENT": 0.2075037419592322, "TOZINAMERAN": 11.244591688467043, "TRELEGY": 2.669873505943685, "VAXZEVRIA": 0.9290139685602596, "XELJANZ": 0.9284387838415604, "null": 0.658241284148341}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2251.json
index 8ed88b6bc05..c2ed146b6e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2251.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2251.json
@@ -1 +1 @@
-{"AMIKACIN": 28.48454022944031, "AMINOSALICYLIC": 5.612989687967537, "DEXAMETHASONE": 3.015704647640087, "EXJADE": 4.165618786056417, "GARDASIL": 1.8647706501726893, "KEYTRUDA": 1.4270764572445576, "PEGASYS": 1.3666867400608254, "REVATIO": 9.409931976434848, "TOZINAMERAN": 1.15170527195404, "VFEND": 6.348587119684815, "ZOSTAVAX": 3.2207353680896342, "null": 1.446642760311605}
\ No newline at end of file
+{"ENTRESTO": 51.483650746269966, "null": 0.6689478346502192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2252.json
index dd17a3f6d18..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2252.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2252.json
@@ -1 +1 @@
-{"null": 2.579042981685236}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2253.json
index 5c4881e3438..faa6172baa6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2253.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2253.json
@@ -1 +1 @@
-{"ABATACEPT": 3.366378395477557, "AMIKACIN": 49.65664319903518, "AMINOSALICYLIC": 3.975890909407739, "ARAVA": 1.3218493846321997, "BEDAQUILINE": 7.786492816151993, "BRIDION": 7.270561107986666, "CASPOFUNGIN": 13.223666380999967, "ENBREL": 2.1154314104426546, "EXJADE": 2.751221742200725, "GARDASIL": 1.0243302024644108, "KEPPRA": 1.1821719937694883, "NOT": 12.530174202446329, "PEGASYS": 1.9800667811338304, "PEGINTERFERON": 9.773174139675096, "PEGINTRON": 2.7178549290624803, "SHINGRIX": 1.716755838781915, "SIMPONI": 1.50824660384977, "TOBRAMYCIN": 46.524488193918536, "TOZINAMERAN": 1.5772117363132037, "VIAGRA": 4.574890635439518, "ZOSTAVAX": 24.907899836589124}
\ No newline at end of file
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2254.json
index 7e50d9cedb3..3ada9e8e40c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2254.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2254.json
@@ -1 +1 @@
-{"ACETYLSALICYLIC": 1249.3627683550633, "ARAVA": 11.25520099102776, "TOZINAMERAN": 1.4801112897930775, "VIAGRA": 18.932642715529937}
\ No newline at end of file
+{"AVANDIA": 7.3568156913836145, "CELLCEPT": 6.826024908579745, "COMIRNATY": 0.5112104003330681, "FENTANYL": 4.754391190949352, "SPIKEVAX": 0.2018812593898281, "SUBOXONE": 6.242236960907431, "ZYPREXA": 3.188004540090515, "null": 1.1605405950421137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2255.json
index 24dc1cf28e5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2255.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2255.json
@@ -1 +1 @@
-{"COMIRNATY": 1.405020958254909, "EXJADE": 2.863145960057348, "HUMALOG": 2.97294524011579, "JARDIANCE": 1.068697363435881, "LANTUS": 1.5701611582761223, "MIDAZOLAM": 3.3243087264971245, "PEGASYS": 2.271282694386239, "PEGINTRON": 1.190429502108967, "REVATIO": 4.510996090418813, "SHINGRIX": 2.586832722419568, "SIMPONI": 1.0603113439492642, "SPIKEVAX": 1.9374111269547416, "STELARA": 1.1272648708523694, "TOZINAMERAN": 3.7042892082115353, "VIAGRA": 12.43748808646233, "XELJANZ": 1.2411156647521586, "ZOSTAVAX": 3.98832658817158}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2256.json
index c33a8a280ad..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2256.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2256.json
@@ -1 +1 @@
-{"ADCIRCA": 1.206315583855787, "ADVAGRAF": 2.763138541139967, "ADVATE": 1.1984156532733252, "AFINITOR": 3.1521652151322668, "ALIMTA": 2.133419272886312, "AMBRISENTAN": 1.3507673599351673, "ANGIOX": 2.177920083353408, "ARANESP": 8.113063000537679, "ARZERRA": 2.532092513273746, "ATEZOLIZUMAB": 1.13794704010517, "AVANDAMET": 1.2409826932492474, "AVANDIA": 4.279523755190527, "AVELUMAB": 2.099160638053909, "AXICABTAGENE": 1.1677098340825154, "AZACITIDINE": 1.57026882930361, "BARACLUDE": 4.024978053400881, "BAVENCIO": 1.413957370912435, "BEDAQUILINE": 1.6745076965757852, "BELANTAMAB": 4.117188296088964, "BENZODIAZEPINE": 5.4352271378574, "BENZODIAZEPINES": 2.720269185565836, "BETA": 1.8112886306365088, "BIKTARVY": 1.1407651737365463, "BINIMETINIB": 1.408231479707439, "BIVALIRUDIN": 2.9572882957974014, "BOSULIF": 1.552915835226151, "BRAFTOVI": 10.07322255904154, "BREXPIPRAZOLE": 1.4582249053177383, "BUPRENORPHINE": 2.657805406220246, "BYETTA": 1.252354881526066, "CANCIDAS": 3.3784343330732667, "CAPRELSA": 1.2394090668766289, "CARDIAC": 30.24376155033592, "CARFILZOMIB": 1.8458697681408605, "CARMUSTINE": 1.1555727303759808, "CASPOFUNGIN": 1.8007610321807277, "CELLCEPT": 1.111198003695945, "CELSENTRI": 1.129557203130097, "CINACALCET": 13.156405955651817, "COLESEVELAM": 5.762492945999524, "COLOBREATHE": 3.7444808560178986, "COMTAN": 1.1683708365177088, "COTELLIC": 3.509511679071972, "CRESEMBA": 8.913182427818843, "CUBICIN": 2.2522732678909376, "CYTARABINE": 1.278405624519404, "DAKLINZA": 1.0038234044881156, "DARATUMUMAB": 1.778234301963921, "DARBEPOETIN": 1.9547203097925647, "DARZALEX": 1.3400309963610355, "DAURISMO": 19.576393406500067, "DEFITELIO": 2.3846036722228083, "DELAMANID": 1.012469703631057, "DESCOVY": 1.3174577629110291, "DEXAMETHASONE": 1.083486759221047, "DIFICLIR": 2.236498412976659, "DRUG": 1.7239785499571212, "DULOXETINE": 1.522482729924633, "ECULIZUMAB": 1.6207875589752312, "ELIQUIS": 2.146146171531744, "EMEND": 2.8770921260801754, 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"RANOLAZINE": 6.898066994844456, "RAPAMUNE": 1.9662207551987307, "REGORAFENIB": 1.1287524753608495, "REMDESIVIR": 8.945811105956519, "REVATIO": 9.34331435642017, "REVLIMID": 1.8396011581134508, "RILUTEK": 4.225347330789885, "RILUZOLE": 17.58785499525715, "ROACTEMRA": 1.2232441803933252, "ROSIGLITAZONE": 2.628977326013082, "RUBRACA": 3.946058961384429, "RYDAPT": 2.6702350341078445, "SILDENAFIL": 1.5353624771276806, "SIMEPREVIR": 2.070935707180888, "SIRTURO": 2.4279047452921247, "SOFOSBUVIR": 2.2323323476761026, "SOLIRIS": 1.870081089499524, "SOTORASIB": 1.311793631693534, "SOVALDI": 2.0131114079317567, "SPINRAZA": 2.7638602143759345, "SPRYCEL": 3.0955379074819898, "STALEVO": 1.2563767580769625, "STIVARGA": 2.408789695133592, "SUBOXONE": 1.2474467661687936, "SUTENT": 5.636203431318115, "SYCREST": 1.4046187066039229, "SYMTUZA": 1.8771834566897925, "SYNAGIS": 2.1160429983675155, "TAFINLAR": 6.644593702886772, "TAGRISSO": 1.4521250211176764, "TAMIFLU": 1.3257216209782416, "TARCEVA": 1.555971067362755, "TASIGNA": 2.1819640638041244, "TEMODAL": 2.3231587938627483, "THALIDOMIDE": 3.432036286069746, "TIVICAY": 1.0410078365974171, "TOBI": 2.662542502907519, "TORISEL": 4.208830709779996, "TRACLEER": 10.7464331906387, "TRELEGY": 9.091756758002507, "TREMFYA": 1.172655967332053, "TRODELVY": 5.879185040003085, "TWYNSTA": 1.1258752915549504, "UNKNOWN": 5.054482790600991, "UNSPECIFIED": 8.133131237001775, "UPTRAVI": 1.2073043805410668, "VEKLURY": 7.301323382850774, "VELCADE": 1.0680869479633135, "VELTASSA": 18.584711376729523, "VEMLIDY": 1.8181009190523372, "VEMURAFENIB": 1.374219531785746, "VENCLYXTO": 2.33199452098539, "VENETOCLAX": 1.8765645454774964, "VFEND": 2.669613913128396, "VIAGRA": 2.539503134301037, "VIGABATRIN": 1.9955967929350196, "VOTRIENT": 11.220792342365764, "VYXEOS": 1.5852877668497476, "XALKORI": 7.98864785379812, "XEPLION": 1.043687431226187, "XOFIGO": 4.442159241223041, "XTANDI": 11.995366495415595, "YERVOY": 7.314046515584372, "YESCARTA": 3.5292376209164846, "YONDELIS": 1.663377006918176, "ZAVESCA": 3.932510598955923, "ZELBORAF": 5.927415486900074, "ZEPATIER": 1.9337834569397383, "ZERIT": 1.0347431104427005, "ZYPREXA": 1.280308709422877, "null": 1.237011493908171}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2257.json
index c6fe2f5d4da..96b3835d685 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2257.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2257.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.1558890440770555, "ARAVA": 1.0417398362502988, "COMBIVIR": 20.711876675652128, "ENFUVIRTIDE": 478.73827759828566, "null": 2.0167291437154518}
\ No newline at end of file
+{"null": 0.9994281994518696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2258.json
index f99f59f6304..eb3d265ad85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2258.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2258.json
@@ -1 +1 @@
-{"null": 1.3463334655846508}
\ No newline at end of file
+{"COMIRNATY": 0.893364697128218, "TOZINAMERAN": 5.243089281848847, "null": 0.6557092824839}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2259.json
index a26c0363373..0d49d3f7af6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2259.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2259.json
@@ -1 +1 @@
-{"CICLOSPORIN": 32.61734257162428, "JARDIANCE": 18.30986879328162, "null": 1.0114721767413046}
\ No newline at end of file
+{"EXJADE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/226.json
index bf5dfc458d7..9a653105361 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/226.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/226.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.646115471151065, "ALEMTUZUMAB": 1.144918699815329, "ALIMTA": 1.122873910523572, "ANAKINRA": 10.160710950054884, "ATAZANAVIR": 7.97963607195084, "AVAMYS": 2.5492370835868856, "AXITINIB": 11.393833915921212, "BAVENCIO": 29.40566573794465, "BRAFTOVI": 2.622236908451458, "BUDESONIDE": 6.692390531629411, "CABOMETYX": 9.046682715422463, "DEXAMETHASONE": 2.764855564979181, "DOXORUBICIN": 1.845891541209162, "DULOXETINE": 2.367037650201471, "EMPAGLIFLOZIN": 10.272192357951718, "EMTRICITABINE": 3.258032587139684, "ENOXAPARIN": 2.244201969131368, "FASENRA": 2.9001564677388982, "FLUTICASONE": 4.052672897884921, "HYDROCORTISONE": 21.786673113041044, "INLYTA": 4.534322146058072, "IPILIMUMAB": 27.10040061042941, "IRON": 5.932005371640996, "JARDIANCE": 2.497138464501347, "KALETRA": 3.815296748426225, "KEYTRUDA": 49.96298620275996, "KIVEXA": 8.495009555188792, "LENVIMA": 8.930942728376815, "LIBTAYO": 12.824907575127687, "LOPINAVIR": 6.978243687677841, "LYSODREN": 44.281390988049765, "MEPOLIZUMAB": 4.271972979015433, "MITOTANE": 143.74734735871854, "NORVIR": 12.192195844638164, "NOXAFIL": 3.9711009107998536, "NUCALA": 1.8669004077197424, "OMALIZUMAB": 1.063320845318836, "OPDIVO": 89.26868147766206, "PEMBROLIZUMAB": 12.209168077941726, "RELVAR": 5.576907565481223, "RITONAVIR": 47.04643325988366, "VFEND": 1.5889864494253756, "VORICONAZOLE": 2.0674348526239985, "XOLAIR": 1.148627775928159, "YERVOY": 20.863380297241548}
\ No newline at end of file
+{"null": 7.555558268535589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2260.json
index 6547e6d67ff..dd161db73cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2260.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2260.json
@@ -1 +1 @@
-{"null": 1.1495562290499932}
\ No newline at end of file
+{"null": 1.5608023183884372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2261.json
index 11e8c1c1157..a0f2bb86f63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2261.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2261.json
@@ -1 +1 @@
-{"null": 1.840512258020596}
\ No newline at end of file
+{"null": 5.663050942805535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2262.json
index d18123b0304..e815017ff28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2262.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2262.json
@@ -1 +1 @@
-{"null": 4.122521220703462}
\ No newline at end of file
+{"SPIKEVAX": 3.478635973324953, "null": 1.0035202771450589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2263.json
index 4f751e8a2f4..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2263.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2263.json
@@ -1 +1 @@
-{"CYMBALTA": 177.51824932240976}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2264.json
index 01847ecdacd..61e7276b628 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2264.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2264.json
@@ -1 +1 @@
-{"null": 2.431575004969513}
\ No newline at end of file
+{"ABILIFY": 0.877750054939515, "ACLIDINIUM": 60.81870293394235, "ADALIMUMAB": 2.9318401478246763, "AFINITOR": 0.6928163707934364, "ANORO": 3.4606675284303416, "AVAMYS": 7.888876813939498, "AVANDIA": 3.039899499693559, "BENRALIZUMAB": 13.765966130155894, "BUDESONIDE": 1.7148474284648436, "BYETTA": 3.011778049493324, "CICLOSPORIN": 0.6074451069108004, "CIMZIA": 0.3974698180895518, "CLOPIDOGREL": 0.5843063689095397, "COMBIVIR": 16.44928080986794, "COMIRNATY": 0.1188589257133573, "ELIQUIS": 0.2879730360016907, "ENTRESTO": 2.148472368833928, "EPIVIR": 3.982613329617241, "EXJADE": 3.606484747885607, "GARDASIL": 0.8965479330007105, "HUMALOG": 1.147358979980128, "IBRANCE": 0.4117258546003942, "IBUPROFEN": 0.9365760328884196, "INSULIN": 3.397474866619421, "ISENTRESS": 8.512409421859859, "JANUMET": 3.349362342927, "JANUVIA": 3.010871062150327, "JARDIANCE": 0.5758352052261092, "KALETRA": 2.4204009370316686, "KEPPRA": 1.0345753372836697, "LAMIVUDINE": 5.138688176925462, "MEPOLIZUMAB": 3.9400968666861353, "PANTOPRAZOLE": 2.3606150213906227, "PEGASYS": 0.7648502441210542, "PEGINTERFERON": 1.718494587334065, "PEGINTRON": 0.5948365565267363, "RIVAROXABAN": 10.941615364880697, "ROTATEQ": 1.931332507019483, "SPIKEVAX": 0.0647533366477251, "SUBOXONE": 0.7929677886129962, "TOZINAMERAN": 0.5063084193977728, "VAXZEVRIA": 0.1450739431425641, "ZOSTAVAX": 3.321124916689808, "ZYPREXA": 1.501277636248486, "null": 2.5928043737289856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2265.json
index 11dcdeff6f6..76005f9c027 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2265.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2265.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 1.2503775383871962, "ATRIPLA": 10.947278419036037, "AVANDIA": 1.9853148465509751, "COMTAN": 5.06970309985907, "ESBRIET": 1.417031076445273, "FASENRA": 3.4317578075328647, "FENTANYL": 1.24064087174644, "GARDASIL": 2.321012922317694, "INFLIXIMAB": 54.36259970695628, "JAKAVI": 1.8791162616676145, "KEPPRA": 1.583647680373985, "KEYTRUDA": 1.775487784787096, "LATUDA": 3.881731015195834, "MEPOLIZUMAB": 12.563517873260036, "NUCALA": 4.226112438147708, "OLANZAPINE": 1.6842484932221682, "OMALIZUMAB": 1.620748529485593, "OPSUMIT": 1.8142709989968169, "ROTATEQ": 3.141866625260112, "STRIBILD": 8.72562595648275, "TRACLEER": 1.188877939554129, "TRUVADA": 6.27635512038181, "VIREAD": 6.932719736180123, "XTANDI": 1.3159658180591405, "ZYPREXA": 1.5835152710238969}
\ No newline at end of file
+{"null": 1.0060728874517513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2266.json
index d8d36d5b9ae..019342fdabb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2266.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2266.json
@@ -1 +1 @@
-{"ABEMACICLIB": 1.4466796293005717, "ABRAXANE": 1.6140702065535653, "ACETYLSALICYLIC": 7.199476609854669, "ADALIMUMAB": 1.7897537694326602, "ADCETRIS": 1.1199012710851095, "ADEMPAS": 1.0189059952936403, "AFINITOR": 2.292394012593065, "AFLIBERCEPT": 1.7902295604743452, "ALDARA": 1.18647607604891, "ALIMTA": 2.4469540187018746, "ALPELISIB": 3.3957480849402053, "AMBRISENTAN": 1.4172080446907016, "APREMILAST": 2.591977508052677, "ATEZOLIZUMAB": 1.2736260573831677, "AVASTIN": 2.619136987014389, "AVELUMAB": 1.5963027783469896, "AXITINIB": 2.9149107005178125, "BAVENCIO": 1.8649008024515004, "BEDAQUILINE": 2.326960967715916, "BEVACIZUMAB": 1.928557314449017, "BEXSERO": 2.777760909669821, "BINOCRIT": 1.4218816165059982, "BOCEPREVIR": 1.6712408645107135, "BOSULIF": 1.7455119393002352, "BRAFTOVI": 2.4815546485938342, "BREYANZI": 3.2002757513401945, "BRINTELLIX": 1.6047694073220735, "BYDUREON": 2.4648638895146715, "BYETTA": 2.1198243372872647, "CABAZITAXEL": 1.351551700102024, "CABOMETYX": 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1.7681188587635457, "SIRTURO": 1.730420688134834, "SORAFENIB": 1.7176290311387008, "SOTORASIB": 1.2046685799745216, "SOVALDI": 1.333545193581687, "SPIRONOLACTONE": 1.4711829812926718, "SPRYCEL": 1.156659191559647, "STALEVO": 1.0109154616597298, "STIRIPENTOL": 15.524465486091248, "STIVARGA": 3.940230375813604, "STOCRIN": 1.5083720916931278, "SUNITINIB": 2.062683688096459, "SUTENT": 4.008740862829962, "TAGRISSO": 3.320458532718724, "TARCEVA": 1.5695642399425114, "TAXOTERE": 1.6518701837772098, "TEDUGLUTIDE": 1.679603996072584, "TEGAFUR": 7.484137183796419, "TEMODAL": 1.0873516825350602, "TEMSIROLIMUS": 1.476436137223385, "TERIPARATIDE": 1.3290999176696074, "THERAPEUTIC": 4.975512483857825, "THIOTEPA": 1.0451735811405387, "TOPOTECAN": 1.743633936092128, "TORISEL": 1.3758481107111524, "TRASTUZUMAB": 1.2327664819345014, "TRESIBA": 1.087937718100836, "TRIUMEQ": 1.0069376626356583, "TRODELVY": 1.2083083678773563, "TRULICITY": 4.66038886323866, "UPTRAVI": 1.7094932741822402, "VAXZEVRIA": 1.16615760281183, "VECTIBIX": 2.19750841807612, "VELMETIA": 1.0800310441650258, "VEMURAFENIB": 1.0133164262444592, "VICTOZA": 2.810757746304368, "VILDAGLIPTIN": 1.0453159016766262, "VOTRIENT": 3.903263948456488, "XALKORI": 2.2346498787395888, "XELODA": 3.037550371822953, "XGEVA": 1.6352010708974924, "XOFIGO": 2.66011209923953, "XTANDI": 5.038737498830942, "YERVOY": 1.483525156605557, "YONDELIS": 1.0350401019438875, "ZEJULA": 1.5250484293733555, "ZELBORAF": 2.972018384244621, "ZEPATIER": 1.422834675923114, "ZOMETA": 1.0117182411287051, "ZYCLARA": 2.670832543963208}
\ No newline at end of file
+{"null": 0.4894537929896228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2267.json
index eb17a81bce4..d6f80cb0354 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2267.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2267.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 50.29139779731898, "null": 1.8784027870157576}
\ No newline at end of file
+{"EVEROLIMUS": 1370.9472851697726, "null": 0.489587685703479}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2268.json
index 86100070892..fa7ba6c05bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2268.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2268.json
@@ -1 +1 @@
-{"ABACAVIR": 21.23767603914714, "AIMOVIG": 1.207655576881096, "BENLYSTA": 8.93098225373147, "COSENTYX": 5.529363435880501, "ENBREL": 1.6323288421804312, "FULVESTRANT": 20.96056018690132, "GARDASIL": 2.943925815988416, "IBRANCE": 49.93352861905284, "INLYTA": 2.0287432523324465, "KISQALI": 22.14361000558108, "METHOTREXATE": 1.1987292164414072, "NUCALA": 2.020636795964992, "PANTOPRAZOLE": 9.80154880107053, "PEGINTRON": 3.022503091221117, "PLEGRIDY": 3.8727425878296766, "SIMPONI": 7.978786524003997, "STELARA": 3.09993640198383, "SUTENT": 7.925060994124159, "TREMFYA": 4.471403261441751, "XELJANZ": 10.190129969481374}
\ No newline at end of file
+{"null": 1.447124326856896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2269.json
index a71c70b0b87..87f5d8b7255 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2269.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2269.json
@@ -1 +1 @@
-{"APIDRA": 86.5598897231919}
\ No newline at end of file
+{"APIDRA": 2.707573804689044, "AVANDAMET": 14.58077631782412, "AVANDIA": 16.313545370563542, "BENLYSTA": 2.7978749982041404, "COMIRNATY": 0.0274008450678688, "ELIQUIS": 1.8324658983809037, "HIZENTRA": 4.954489909774196, "HUMALOG": 1.756124249111601, "IBRANCE": 0.8982559718288611, "INCRUSE": 7.908916315228619, "INSULIN": 1.7823452614241564, "JANUMET": 6.2699708927515045, "JANUVIA": 3.0833737713961327, "JARDIANCE": 20.49672181622783, "LANTUS": 13.575710761140618, "LEVEMIR": 8.342879689224205, "NOVORAPID": 2.4276887301309604, "NPLATE": 3.292851521059287, "NUCALA": 1.320787499701421, "OPSUMIT": 9.172735993689244, "PLAVIX": 2.0833209409675955, "RANOLAZINE": 38.77372094667076, "ROSIGLITAZONE": 52.14395134093398, "SIMPONI": 2.5649185066642874, "STELARA": 2.144960065863128, "SYNAGIS": 95.26774454518748, "TRACLEER": 7.013534234440036, "TRELEGY": 11.457101893131034, "TREMFYA": 4.714499057431661, "VELTASSA": 23.730704008947303, "XELJANZ": 1.9564309844611152, "XTANDI": 1.425894778189702, "ZOSTAVAX": 2.415311531013624, "null": 1.0323700569635244}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/227.json
index 41d117dd5dc..13f6189c883 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/227.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/227.json
@@ -1 +1 @@
-{"BYETTA": 27.44076390190085, "JANUMET": 51.4486755151742, "JANUVIA": 31.49953015406459}
\ No newline at end of file
+{"null": 0.3511171371258133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2270.json
index 2fce891f0e3..ba3ea7b6b6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2270.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2270.json
@@ -1 +1 @@
-{"ABILIFY": 3.9465863074468337, "ANTIBIOTICS": 41.17722194602349, "AUBAGIO": 25.25274765279286, "CHAMPIX": 10.753986066006012, "CYMBALTA": 2.8800291998215943, "HYDROCORTISONE": 29.50955484596742, "KEPPRA": 1.466268083535507, "OLANZAPINE": 3.404417598105121, "XTANDI": 3.500845114834425, "ZYPREXA": 2.7069383970640644, "null": 1.8992472870244763}
\ No newline at end of file
+{"ARANESP": 13.147021519604216, "COMIRNATY": 0.096344991247751, "ENTRESTO": 9.904013835479198, "TRACLEER": 15.925781071101683, "null": 1.9639431522662003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2271.json
index dc81e1c9e44..b56e3c09c77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2271.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2271.json
@@ -1 +1 @@
-{"CYMBALTA": 4.58100827507504}
\ No newline at end of file
+{"OPSUMIT": 52.07591617029961, "null": 1.5859616200385516}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2272.json
index a6ffbc05beb..6395da9e5f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2272.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2272.json
@@ -1 +1 @@
-{"ARANESP": 1.7095790304413043, "AUBAGIO": 2.850668275872124, "BUPIVACAINE": 8.954260144522411, "CABOMETYX": 3.3648240365173456, "CYMBALTA": 1.6535225740751291, "ELIQUIS": 1.862942016088286, "FASLODEX": 2.160165154920504, "HUMALOG": 1.0151387084994965, "IBRANCE": 1.382092918276841, "JANUMET": 6.142129817724489, "JANUVIA": 3.0408725616524674, "JARDIANCE": 1.4597776342099418, "KEPPRA": 1.3429562693765982, "KEYTRUDA": 1.293418301161969, "LANTUS": 2.2906985771402444, "OCEAN": 276.19978532385227, "OLANZAPINE": 2.8332524394686125, "OPTIMARK": 4.025311048765015, "OXYBUTYNIN": 15.403207351665197, "PLAVIX": 2.066303273499224, "SIMPONI": 1.1095359909523128, "SUTENT": 6.584985154215838, "XELJANZ": 1.5896516189647931, "XTANDI": 1.319131419098881, "ZYPREXA": 3.724063753471079, "null": 1.209242141428616}
\ No newline at end of file
+{"ANORO": 4.870767357536254, "AVANDAMET": 19.937834517446312, "AVANDIA": 25.08712462002974, "BYETTA": 2.6532263708259225, "COMIRNATY": 0.1393624106201859, "ELIQUIS": 11.06196511260295, "FORSTEO": 2.582728309175193, "HUMALOG": 1.2540096649142665, "HUMIRA": 3.71327773196224, "JANUMET": 3.7211558858104175, "JANUVIA": 6.972863985995172, "JARDIANCE": 3.255330997879454, "LANTUS": 4.281319998990235, "OPSUMIT": 7.808743912822477, "PLAVIX": 3.9812386747678095, "RANOLAZINE": 30.689058500274395, "SPIKEVAX": 0.2694625231901148, "TRACLEER": 5.623846725932027, "TRELEGY": 8.637504772323544, "VELTASSA": 7.452652347562415, "VIMPAT": 6.16087547004473, "XELJANZ": 0.7558820337485042, "XTANDI": 1.253178363445103, "ZOSTAVAX": 2.6986796858714057, "null": 1.4297244142426548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2273.json
index fa018f6a390..71e9bbf3446 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2273.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2273.json
@@ -1 +1 @@
-{"null": 1.3805811357358588}
\ No newline at end of file
+{"null": 2.278058895532269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2274.json
index e5b6e2d6436..8d11aa30570 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2274.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2274.json
@@ -1 +1 @@
-{"ALIMTA": 1.4415272176905771, "AMINOSALICYLIC": 1.1028847619798594, "ANAKINRA": 6.951022350424736, "ARANESP": 1.239636672163659, "ARIXTRA": 2.794004113644586, "ASPARAGINASE": 1.7167700977949394, "AVASTIN": 3.380159359957968, "BEVACIZUMAB": 2.5416181255160417, "BORTEZOMIB": 1.7278903320365704, "BYETTA": 1.824953149335576, "CABOMETYX": 1.0844887952362825, "CANAGLIFLOZIN": 3.876863225205865, "CARFILZOMIB": 2.2046150290681408, "CELECOXIB": 1.2253768784074364, "CINRYZE": 1.8961144281797415, "COMIRNATY": 1.094116265075767, "COVID19": 1.930051713395495, "DARATUMUMAB": 2.0410990548424874, "DEXAMETHASONE": 2.050174562664356, "DOXORUBICIN": 1.805410796518077, "EBIXA": 3.4092784052383385, "ELIQUIS": 6.079256972686195, "ENOXAPARIN": 5.708584065492969, "EPOETIN": 2.58090204766743, "ESMYA": 2.775890462735965, "EVENITY": 1.5724165346633314, "EVISTA": 32.65772922721633, "EVRA": 7.039769491270097, "EVUSHELD": 3.1638762042795, "FASLODEX": 1.1967657059071182, "FILGRASTIM": 1.040979349587184, "HIZENTRA": 1.1053926183959146, "HUMAN": 2.500717685911884, "ICLUSIG": 1.4783273941410373, "INHIXA": 5.571379507893011, "JANUMET": 1.078082781804724, "JANUVIA": 1.000530005429645, "KIOVIG": 1.249160443653147, "KYPROLIS": 2.505526223715434, "LIXIANA": 1.4912842982850625, "NOVOSEVEN": 20.65426123238788, "NPLATE": 6.6693390811726845, "OLANZAPINE": 1.286610423824885, "OSIMERTINIB": 3.057609333367075, "PEGASYS": 1.2240280427723111, "PLAVIX": 1.1568302501692256, "PRADAXA": 1.0885077056593806, "PRIVIGEN": 1.55075040216488, "PROTELOS": 18.976521298233443, "RAPAMUNE": 2.814376747756138, "REVLIMID": 2.899802729467226, "RINVOQ": 4.713727064858936, "RIVAROXABAN": 4.7615426551943605, "ROACTEMRA": 1.1477294906585542, "SOLIRIS": 1.2421275091852129, "STELARA": 1.07666996694104, "TAGRISSO": 2.185114127131098, "TEMODAL": 1.542777180582382, "TEMOZOLOMIDE": 1.403446697722236, "TESTOSTERONE": 15.49091109553344, "THALIDOMIDE": 12.461071063351248, "TOCILIZUMAB": 1.4528879774755696, "TOFACITINIB": 5.057627676767332, "UPADACITINIB": 3.000820755386802, "VAXZEVRIA": 1.6420039180930035, "VELCADE": 2.198939800892246, "XALKORI": 1.518501382813598, "XARELTO": 7.124183162691977, "XELJANZ": 1.6747277791684578, "XOLAIR": 1.007110915574182, "ZOMETA": 2.0029373390952188, "ZYPREXA": 1.5389358461898668}
\ No newline at end of file
+{"null": 1.4613736659054382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2275.json
index d07ac03607d..109ef79acb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2275.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2275.json
@@ -1 +1 @@
-{"ABATACEPT": 35.64437564301909, "ADALIMUMAB": 100.9902381604967, "AMINOSALICYLIC": 5.136803969116341, "APREMILAST": 8.384900697958118, "APREPITANT": 27.82150165726569, "ARAVA": 14.772646574690947, "COSENTYX": 2.4346307453061944, "MYCOPHENOLATE": 13.623505003549036}
\ No newline at end of file
+{"null": 0.8215158129056229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2276.json
index e9257eb28de..10dee1e9970 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2276.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2276.json
@@ -1 +1 @@
-{"APIXABAN": 9.745787080363831, "null": 1.2611405950741714}
\ No newline at end of file
+{"null": 0.9225583663233016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2277.json
index 68a2975222d..4d7a1f05877 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2277.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2277.json
@@ -1 +1 @@
-{"AUBAGIO": 2.6236180128357205, "AZATHIOPRINE": 5.980644113780618, "BUDESONIDE": 5.343920771832232, "BUPRENORPHINE": 3.314984310491812, "COSENTYX": 3.992513109940826, "ENTYVIO": 38.80902748119965, "HUMIRA": 11.902482273665877, "REMSIMA": 138.6835707644756, "STELARA": 6.1005318686765335, "TEDUGLUTIDE": 132.73646066353425, "XELJANZ": 9.216738208184816, "null": 1.2137513814189715}
\ No newline at end of file
+{"null": 0.6780206922776975}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2278.json
index 21eb8bd791d..b384b6e4947 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2278.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2278.json
@@ -1 +1 @@
-{"null": 2.4852296067555475}
\ No newline at end of file
+{"COMIRNATY": 0.5535500175775008, "null": 0.3205333506122504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2279.json
index beb21bfad8d..27722d6c4b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2279.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2279.json
@@ -1 +1 @@
-{"null": 3.1582598847212897}
\ No newline at end of file
+{"ALISKIREN": 66.84979291840278, "METHOTREXATE": 78.03802884891103, "null": 1.938508413867413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/228.json
index f6a84394a34..62acaa51bf6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/228.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/228.json
@@ -1 +1 @@
-{"BUDESONIDE": 19.06480719381573, "FLUTICASONE": 283.42100845542467, "HYDROCORTISONE": 80.51600253342541, "KALETRA": 10.21073323652273, "LOPINAVIR": 156.4809383579694, "RITONAVIR": 187.3555018347998, "STRIBILD": 6.897087185349649, "null": 2.2281594077974782}
\ No newline at end of file
+{"BONVIVA": 1200.2870037727855, "null": 0.6889960300876995}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2280.json
index fb2188eaaed..1566d5fde92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2280.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2280.json
@@ -1 +1 @@
-{"null": 1.7928221752654427}
\ No newline at end of file
+{"null": 1.8527907780345887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2281.json
index adb46db30da..0b8683d2568 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2281.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2281.json
@@ -1 +1 @@
-{"ABATACEPT": 8.234308422778563, "ADALIMUMAB": 7.511963735757865, "ANAKINRA": 94.89663659365397, "ARAVA": 4.822640778587149, "BEOVU": 7.856880717763529, "CONTRAST": 78.4155383283577, "COSENTYX": 1.9489474031976692, "ENBREL": 3.6368264206230574, "HUMIRA": 1.5451915809093038, "LEFLUNOMIDE": 9.379888225363912, "METHOTREXATE": 1.338087187058188, "OPTIMARK": 89.81360511996223, "PLAVIX": 3.644726580040652, "null": 1.6536456475611747}
\ No newline at end of file
+{"null": 2.0429003166584043}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2282.json
index f830825fd75..741d1b23a2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2282.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2282.json
@@ -1 +1 @@
-{"null": 2.7599328232409817}
\ No newline at end of file
+{"SPIKEVAX": 5.980968731869647, "null": 1.678978955745374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2283.json
index f7cf302e906..370c60ece4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2283.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2283.json
@@ -1 +1 @@
-{"ESMYA": 6549.056260896661}
\ No newline at end of file
+{"null": 1.7201077557195354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2284.json
index 8353412f702..1b41aed0286 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2284.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2284.json
@@ -1 +1 @@
-{"ATRIPLA": 42.43603717294686, "EFAVIRENZ": 48.23030616465416, "STRIBILD": 38.18806742020685, "TRUVADA": 19.51880637956595}
\ No newline at end of file
+{"ANGIOX": 99.2925357550834, "AVANDIA": 2.277359406197589, "AXICABTAGENE": 47.35308898612319, "BRILIQUE": 13.194923829483663, "BUSULFAN": 5.505084020878415, "CELLCEPT": 2.3023217465307817, "CLOPIDOGREL": 9.500841753139676, "COMIRNATY": 0.3595916104660277, "CYTARABINE": 3.167779705095913, "EFIENT": 35.57768761718435, "ELIQUIS": 6.626936865590039, "INTEGRILIN": 35.392869542997, "JAKAVI": 6.200842882617498, "KEYTRUDA": 7.992303099230582, "LEVOFLOXACIN": 3.341324303727634, "PEMBROLIZUMAB": 4.039601876622272, "PLAVIX": 1.5091589361090287, "SPIKEVAX": 0.2468936277151052, "TAGRISSO": 5.463955370606241, "TAMIFLU": 2.7500536366681376, "TASIGNA": 4.11308373402036, "TOZINAMERAN": 0.4720742462406315, "TRACLEER": 2.36056650742856, "VAXZEVRIA": 0.0820250177614378, "null": 0.8811746887072791}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2285.json
index f40d8edf5e5..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2285.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2285.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 369.3459951479402}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2286.json
index 6b0a9518204..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2286.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2286.json
@@ -1 +1 @@
-{"ACTRAPID": 771.4370357557297}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2287.json
index 50cd16be114..e4079eb49c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2287.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2287.json
@@ -1 +1 @@
-{"ABRAXANE": 2.809936588812284, "ACTOS": 2.0219064593827034, "ACTRAPID": 1.1172489253104616, "ADENURIC": 1.7303578562369557, "AFINITOR": 2.5633147801284784, "AFLIBERCEPT": 2.335250330116739, "ALIMTA": 2.515387220258124, "ALISKIREN": 1.451844457943944, "ALL": 1.3519056921978867, "ALPELISIB": 1.7166130167551743, "AMBRISENTAN": 1.876214000971121, "ANTIBIOTICS": 2.361467071903381, "APIDRA": 1.0041441594036942, "APIXABAN": 4.10433782734644, "APROVEL": 3.0396340788883616, "ATEZOLIZUMAB": 3.505046874493984, "AVASTIN": 2.584103758227644, "AVELUMAB": 2.1440375839233727, "AXITINIB": 2.3972255478731626, "AZILECT": 1.562496541691703, "BEDAQUILINE": 1.6124851373065985, "BEVACIZUMAB": 2.116388736820449, "BOCEPREVIR": 1.388858070967088, "BOSULIF": 3.0853719706238114, "BRAFTOVI": 3.568813214881859, "BUMETANIDE": 5.133935545247482, "BYDUREON": 2.6537587880092874, "BYETTA": 3.924098721849264, "CABOMETYX": 2.6896844134199736, "CAPECITABINE": 1.8966776370129088, "CAPRELSA": 2.156403652185406, "CARBIDOPA": 1.2326370976276868, "CELECOXIB": 1.5691656328802182, "CELLCEPT": 1.300322305415658, "COAPROVEL": 3.976409313211781, "COBIMETINIB": 1.6858168262038995, "COMTAN": 3.2923144163357216, "COMTESS": 4.819277904395349, "COTELLIC": 1.40614727694638, "CRIXIVAN": 2.097767668797076, "CRIZOTINIB": 4.8795956723444505, "DABRAFENIB": 1.0849252481117468, "DAPAGLIFLOZIN": 2.547903577354684, "DELAMANID": 1.937524721313841, "DEXAMETHASONE": 1.2806842509403404, "DIFICLIR": 2.440967667630874, "DULAGLUTIDE": 4.892722758747175, "EBIXA": 2.7112192767429875, "EMEND": 1.0464132474894494, "EMPAGLIFLOZIN": 6.025391287107175, "ENALAPRIL": 6.559043068384429, "ENTACAPONE": 1.205881987941522, "ENTRESTO": 2.7876152752050283, "ENZALUTAMIDE": 2.584430308430509, "EPCLUSA": 1.1815280263980257, "EPIVIR": 1.3592726510713558, "EPOETIN": 1.7131261900078512, "ERBITUX": 2.568889512851261, "ESBRIET": 1.3361117824140971, "ESOMEPRAZOLE": 2.128004273215487, "EVEROLIMUS": 1.9045520151585151, "EXELON": 2.1841061512066373, "EXFORGE": 1.4602136921725015, "EXJADE": 2.5933876072644275, "EXVIERA": 1.001795909588692, "FASLODEX": 1.6930932867982986, "FEBUXOSTAT": 1.429431571254535, "FENTANYL": 1.3629543902489156, "FIRDAPSE": 2.9407898179763907, "FORXIGA": 8.24253988309443, "FOTIVDA": 5.536733083882675, "GALVUS": 1.000558939658288, "GILENYA": 1.2421172093411046, "GLIBENCLAMIDE": 1.969828672140596, "HERCEPTIN": 1.7014440074007229, "HIZENTRA": 1.6604503968070083, "HUMALOG": 1.4142681420160568, "HYDROCHLOROTHIAZIDE": 1.7655115949338591, "IBRANCE": 1.8793747102646177, "IMBRUVICA": 1.9585808456739928, "INFANRIX": 1.653998066650734, "INLYTA": 4.082085413099716, "INSULIN": 1.492536463969877, "INTRONA": 2.2250388782627497, "INVESTIGATIONAL": 11.001925952899311, "INVOKANA": 9.037702670351509, "IRBESARTAN": 3.490297988187772, "IRINOTECAN": 2.4579145116107908, "IRON": 1.7450457342535577, "JANUMET": 1.9418285778744828, "JANUVIA": 2.44342497821472, "JARDIANCE": 7.893456052401319, "JEVTANA": 2.0130434384440963, "KEYTRUDA": 1.5662875768015614, "LANTUS": 1.1496445970044384, "LENVIMA": 2.9445790959199454, "LEVEMIR": 1.6777887857979965, "LEVODOPA": 1.7062057304212477, "LONSURF": 4.588668462598244, "LUPKYNIS": 3.1530063542706386, "LUTATHERA": 1.3450322303202142, "LYRICA": 1.2713944698152726, "MEKINIST": 2.5350056158082994, "MEMANTINE": 6.914077897941846, "MERCAPTOPURINE": 1.3575122504778658, "METFORMIN": 5.848554704931077, "MICARDIS": 1.886050120051536, "NEULASTA": 2.43310055376882, "NEVIRAPINE": 2.9419843847535723, "NEXAVAR": 1.2024917017319283, "NINLARO": 3.838322056014478, "NIVOLUMAB": 1.3270590908868425, "NOT": 2.349773240712988, "NOVONORM": 1.3744477207568442, "OFEV": 1.9828406248018584, "ONGLYZA": 1.8416172990315856, "OPDIVO": 1.2672322065917625, "OPSUMIT": 1.7137113398627393, "ORENCIA": 1.369028178548791, "OXYBUTYNIN": 2.516671048046541, "OZEMPIC": 7.3989230004802, "PANITUMUMAB": 2.319805337464837, "PANTOPRAZOLE": 2.6206706042209182, "PEGASYS": 2.9914671167591065, "PEGINTERFERON": 1.6046533386113322, "PEGINTRON": 3.4292589433707006, "PEMETREXED": 1.452025721692574, "PERJETA": 2.466418119290907, "PIQRAY": 2.3588537905735776, "PRADAXA": 1.3902438165192863, "RADIATION": 6.001727146308595, "RANOLAZINE": 1.209366253782321, "RAPAMUNE": 1.8975071692587249, "RASILEZ": 1.9912339933645031, "REVATIO": 1.3606157709803743, "REVESTIVE": 8.177235570009085, "REVLIMID": 2.6501426658819045, "ROTASHIELD": 10.289193891678735, "ROTATEQ": 8.225102492971235, "RUBRACA": 5.043125168538401, "RYBELSUS": 3.491864236712261, "SAMSCA": 22.652422742243317, "SAXENDA": 3.79303399970223, "SOLIRIS": 1.1831372439045784, "SOMATROPIN": 3.0906426770053077, "SPINRAZA": 2.5487356148541225, "SPIRONOLACTONE": 4.63280570699531, "SPRYCEL": 1.3006520669562551, "STALEVO": 2.268197778291246, "STIVARGA": 1.3797322185980132, "SUTENT": 3.1335681866950984, "SYNAGIS": 2.777474892233881, "TACROLIMUS": 1.2247081558698538, "TAGRISSO": 1.4237105466240074, "TAMIFLU": 2.0591875460345057, "TAXOTERE": 1.517427556166521, "TELMISARTAN": 1.436274444378154, "TEMSIROLIMUS": 4.06251538057722, "TORISEL": 2.0036839773924124, "TRACLEER": 1.6069297272084366, "TRODELVY": 1.2007306502256514, "TRULICITY": 4.730365555745502, "VECTIBIX": 1.5278776043605111, "VELCADE": 2.380927971795404, "VELTASSA": 3.1049703326345317, "VICTOZA": 6.978558000224387, "VICTRELIS": 6.42501695655817, "VOTRIENT": 2.7440184002632497, "XALKORI": 1.9466514295822412, "XARELTO": 1.0413848872660942, "XELODA": 5.500518065546097, "XOFIGO": 1.585956937598064, "XTANDI": 2.105359393334997, "XYREM": 1.6766682595620803, "YERVOY": 2.942478250078489, "ZELBORAF": 1.6265978743540537, "ZIAGEN": 1.2545109009469928, "ZOMETA": 2.3289602204786526, "ZYPREXA": 1.3201852679214736, "null": 1.4658300596127574}
\ No newline at end of file
+{"null": 0.6328555915525093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2288.json
index f488584e472..949e68baaad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2288.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2288.json
@@ -1 +1 @@
-{"null": 1.7436960170364368}
\ No newline at end of file
+{"AVANDAMET": 11.853169181862691, "AVANDIA": 15.201628810813183, "BUDESONIDE": 2.5821559195074437, "CLOPIDOGREL": 1.426035870493651, "COMIRNATY": 0.1339137370125348, "COSENTYX": 0.9675181480644124, "ELIQUIS": 13.085102562803504, "EVENITY": 6.364659014219273, "FORSTEO": 3.0276647605849765, "HUMALOG": 3.1165519547327434, "IBRANCE": 0.8375239229392302, "LANTUS": 1.745990831279675, "NAGLAZYME": 26.053764349524972, "OPSUMIT": 1.370751934494191, "PLAVIX": 1.5311569538270562, "REVATIO": 7.127429426350858, "SIMPONI": 1.6735215268009522, "SUTENT": 0.9441614626743514, "TOZINAMERAN": 0.1987278131787302, "VIAGRA": 2.673370455057589, "XELJANZ": 1.3536278570877858, "XTANDI": 1.8120598132507628, "ZOSTAVAX": 1.5000803387500947, "null": 1.830454832213414}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2289.json
index 8d5795b77e5..18f273f692d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2289.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2289.json
@@ -1 +1 @@
-{"KEPPRA": 30.663594594694324}
\ No newline at end of file
+{"CUBICIN": 458.9805810301239, "null": 0.6983382272081777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/229.json
index 0e1f8b0268f..00d6613c561 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/229.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/229.json
@@ -1 +1 @@
-{"IPILIMUMAB": 221.59627095045536}
\ No newline at end of file
+{"null": 2.1967878558154603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2290.json
index c90ca5b001e..495fc394388 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2290.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2290.json
@@ -1 +1 @@
-{"null": 1.2706252307038903}
\ No newline at end of file
+{"null": 2.9341242589086303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2291.json
index 7faa2a9caf8..caccaff8a4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2291.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2291.json
@@ -1 +1 @@
-{"null": 2.0464318866351654}
\ No newline at end of file
+{"CUBICIN": 323.29525612114486, "null": 1.0541784347862473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2292.json
index ec308fe99fa..e407cdd2f6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2292.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2292.json
@@ -1 +1 @@
-{"ARANESP": 47.87820750073544, "CELLCEPT": 34.52110111674956, "MYCOPHENOLATE": 213.09868682027556}
\ No newline at end of file
+{"ENTRESTO": 26.397360822912308, "FLUTICASONE": 208.4283184430703, "null": 1.5066391579664802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2293.json
index bf097276538..7e4b4c95642 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2293.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2293.json
@@ -1 +1 @@
-{"PRIVIGEN": 495.6868531747263}
\ No newline at end of file
+{"ASPARAGINASE": 33.34410310302302, "AVANDAMET": 11.341652948128472, "AVANDIA": 11.47684906168181, "BRILIQUE": 4.672600769486689, "CICLOSPORIN": 0.9066005961682844, "CLOPIDOGREL": 6.588180327892893, "COMIRNATY": 0.4143223149951023, "ELIQUIS": 13.476868889309705, "ENTRESTO": 2.868965788929204, "HUMALOG": 0.905838136837288, "JARDIANCE": 1.046150181967475, "NOVOSEVEN": 41.58012002717472, "PLAVIX": 2.287844318343994, "SPIKEVAX": 0.5111168091395446, "SUTENT": 0.6849153694834421, "TOZINAMERAN": 0.507045949016365, "VAXZEVRIA": 0.438125733012882, "XELJANZ": 0.8807001717754736, "null": 0.726740505209767}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2294.json
index 55ccbe83ac9..fe9fb53e246 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2294.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2294.json
@@ -1 +1 @@
-{"BUSULFAN": 129.02125984041857, "null": 1.1813218191891224}
\ No newline at end of file
+{"LANTUS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2295.json
index 2bcd4acf595..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2295.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2295.json
@@ -1 +1 @@
-{"BRIDION": 37.42896680879122, "BUPIVACAINE": 22.254812764510696, "FENTANYL": 65.69867556016085, "MIDAZOLAM": 30.52847124930358, "null": 4.414367719550118}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2296.json
index 20854cd21dd..9867fcab7ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2296.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2296.json
@@ -1 +1 @@
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\ No newline at end of file
+{"ABILIFY": 0.3956464182684186, "ACTOS": 1.9147070505351809, "ADALIMUMAB": 0.2264778071576593, "ALIMTA": 0.6977098049018069, "AMINOSALICYLIC": 0.4345018910565218, "ANAKINRA": 0.5103655684442595, "ANGIOX": 9.684193719005332, "ANTIHISTAMINE": 28.451591621534977, "APIXABAN": 0.4030932951442135, "APROVEL": 3.5116075199547474, "ARIPIPRAZOLE": 3.775844417400084, "ATAZANAVIR": 0.533620473829788, "AVANDAMET": 3.392282987161156, "AVANDIA": 6.213980049469706, "AVASTIN": 0.7448993424165056, "BARBITURATES": 26.3975180191986, "BENZODIAZEPINE": 72.47240226216957, "BENZODIAZEPINES": 19.565107598877976, "BEVACIZUMAB": 0.381789150695521, "BRIDION": 6.100238223142041, "BRILIQUE": 1.6516174131608374, "BUPIVACAINE": 0.6140631030303638, "BUPRENORPHINE": 3.4306046513850283, "BUSULFAN": 0.8565674167481245, "BYETTA": 0.8364176743447657, "CANCIDAS": 1.067141766184603, "CELECOXIB": 1.3183310417369034, "CELLCEPT": 0.4592791110283328, "CICLOSPORIN": 0.2839311577343634, "CLOPIDOGREL": 0.916804882052312, "COMIRNATY": 0.231195135250172, "COMTAN": 1.091266481322884, "COSENTYX": 0.1338275494416251, "CYMBALTA": 0.2750767020800919, "CYTARABINE": 0.8024505102235978, "DARZALEX": 1.1716995683425917, "DEXAMETHASONE": 2.2299250913318, "DEXDOR": 12.93173515765512, "DRUG": 14.186664753926808, "DULOXETINE": 11.181583007596236, "ELIQUIS": 0.6454551010633325, "EMEND": 1.6652974870016215, "ENTRESTO": 0.3681985091202746, "ERBITUX": 1.3377411100940957, "ESBRIET": 0.2693032097422876, "ESOMEPRAZOLE": 1.5728163594839537, "EVENITY": 1.4139781503245694, "EXFORGE": 1.6636621417204325, "EXJADE": 0.3714986544393058, "EXVIERA": 2.293777440128724, "FASENRA": 0.3310281802259707, "FENTANYL": 6.976092458645059, "FORSTEO": 0.2256673086487237, "FORXIGA": 0.4144439775638961, "GALVUS": 1.1638274375572923, "GARDASIL": 0.0753649680735042, "GLIBENCLAMIDE": 1.7615464407235597, "HARVONI": 0.827660376497692, "HUMALOG": 0.2824496631599158, "IBUPROFEN": 6.738354162465168, "ICLUSIG": 1.3847739089322564, "INLYTA": 0.339366399294869, "INSULIN": 0.3037651309354739, "INTRONA": 0.972707449546698, "IRBESARTAN": 4.064952929141512, "IRESSA": 0.5271748011637254, "JANUMET": 0.4806524977981075, "JANUVIA": 1.287804590464197, "JARDIANCE": 0.218580298650439, "JEVTANA": 1.309351724111275, "KALETRA": 0.5665923987561932, "KEPPRA": 0.4438303501806734, "KEYTRUDA": 0.4158511770372505, "KYMRIAH": 0.6566554784033165, "LACOSAMIDE": 3.013959851288462, "LANTUS": 0.1630391965495272, "LEVEMIR": 0.9535174841980968, "LEVETIRACETAM": 1.226614526656293, "LEVOFLOXACIN": 0.4108189587625323, "LINACLOTIDE": 35.21183085038927, "LYRICA": 0.3866622990285284, "MEKINIST": 0.2781648577758735, "MELATONIN": 1.518958809790806, "METHOTREXATE": 0.1396927137088024, "MIDAZOLAM": 5.166385766023574, "MIRCERA": 3.235657699172516, "MUSCLE": 155.41552010783303, "NAGLAZYME": 4.474758849921239, "NEXAVAR": 0.4268840624901235, "NOT": 5.563850512307703, "NOVORAPID": 0.4032330963181399, "NOVOSEVEN": 2.245226836950024, "NPLATE": 0.9895093388167294, "OFEV": 0.4531731495049665, "OLANZAPINE": 5.881487529821581, "OPDIVO": 0.8050245103034089, "OPIOID": 150.16074822092176, "OPIOIDS": 12.917513539631653, "OPSUMIT": 0.8022938443925771, "OPTIMARK": 0.3569185206117676, "OXYBUTYNIN": 1.3105594825992115, "PANTOPRAZOLE": 1.5726295844027862, "PEGASYS": 0.1595666817495686, "PEGINTRON": 0.2815566570739854, "PIOGLITAZONE": 6.227740874401152, "PLAVIX": 0.5299814687379487, "PRADAXA": 2.5605745715425776, "PRAXBIND": 5.181493971611359, "PREGABALIN": 4.429123799325488, "PREVENAR": 2.116104001398313, "PRIVIGEN": 0.4785244621313284, "RASBURICASE": 9.647796496922636, "REBETOL": 1.5361655286826563, "REMDESIVIR": 3.038537372321973, "REVATIO": 1.6275027343978823, "RISPERIDONE": 1.1412906865611838, "RIVAROXABAN": 2.718038399664715, "ROSIGLITAZONE": 13.002599755829332, "ROTATEQ": 0.4383965793386203, "SILDENAFIL": 2.59752040279868, "SIMPONI": 0.1068439095166112, "SOLIRIS": 1.446677639453585, "SPIKEVAX": 0.1609322307512168, "SPINRAZA": 7.501035723460521, "STALEVO": 0.965620529566433, "STELARA": 0.2544635674612656, "SUFENTANIL": 11.00704668139615, "SUTENT": 0.4307346158098542, "SYNAGIS": 2.4308459085667007, "TAGRISSO": 0.5721868012954292, "TAMIFLU": 2.0566040796984324, "TASIGNA": 0.2549106996382427, "TELMISARTAN": 4.826456496855538, "TOZINAMERAN": 0.0396336466616028, "TRACLEER": 2.4925442470817534, "TRELEGY": 0.4601462178658652, "UNKNOWN": 37.14500927552841, "UNSPECIFIED": 59.97668216800808, "VAXZEVRIA": 0.0575563576167022, "VFEND": 0.9192221613438566, "VIAGRA": 0.3788025247980001, "VIMPAT": 1.3979303102368903, "VORICONAZOLE": 0.7079761095335461, "VOTRIENT": 0.2109485056357441, "XARELTO": 1.267689417947847, "XOLAIR": 0.2302588680459933, "XTANDI": 0.3803896291855393, "YESCARTA": 0.6925617052450201, "ZOSTAVAX": 0.1881757790694046, "ZYPREXA": 1.56900387040012, "null": 3.2348505523219373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2297.json
index 7b041e5c9ba..a8362269797 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2297.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2297.json
@@ -1 +1 @@
-{"COVID19": 3.1941370078078286, "MMRVAXPRO": 29.912972887841025, "SPIKEVAX": 2.714958654070412, "TAMIFLU": 48.52835963855505}
\ No newline at end of file
+{"null": 7.456555147927114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2298.json
index ef9f87ed2c2..d7aebaa4561 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2298.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2298.json
@@ -1 +1 @@
-{"null": 2.289587896539256}
\ No newline at end of file
+{"null": 2.03792100853017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2299.json
index 7e4fd9b349f..5f8732af153 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2299.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2299.json
@@ -1 +1 @@
-{"ATOSIBAN": 3975.062946982816, "COMBIVIR": 19.34553140544672, "CYTARABINE": 35.55598148693523, "null": 1.4493896716986856}
\ No newline at end of file
+{"null": 5.8923329929681945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/23.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/23.json
index 59be0f74c6d..5b132407893 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/23.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/23.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1363554145068766, "TWINRIX": 26.63895069127133}
\ No newline at end of file
+{"OPSUMIT": 58.93192408452042, "null": 0.3732177405101867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/230.json
index eb384e8b818..e4867c2b393 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/230.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/230.json
@@ -1 +1 @@
-{"null": 2.8576095853763683}
\ No newline at end of file
+{"COMIRNATY": 2.2958612445942874, "KEYTRUDA": 5.423642573173516, "MEKINIST": 18.542161688061253, "VAXZEVRIA": 0.7925263036062983, "null": 0.3086684807187662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2300.json
index 60e92150f9d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2300.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2300.json
@@ -1 +1 @@
-{"ABILIFY": 8.467168362173059, "ARIPIPRAZOLE": 20.01182156367929, "AZILECT": 8.154149563324761, "BRINTELLIX": 1.5167212237467946, "BUPRENORPHINE": 1.2954088175126408, "CARBIDOPA": 15.291347673380768, "CARIPRAZINE": 47.21875423481784, "CHAMPIX": 5.598183751278615, "COMTAN": 18.32715472714668, "CYMBALTA": 2.0827037403405053, "DAKLINZA": 5.2476077109873644, "DULOXETINE": 4.684125185312821, "ENTACAPONE": 32.72418609728828, "FYCOMPA": 10.619229147939722, "INVEGA": 15.1523578975482, "KAFTRIO": 2.3581720156141506, "KEPPRA": 3.631375750954594, "LACOSAMIDE": 2.9395603900521805, "LATUDA": 18.190018083578504, "LEVETIRACETAM": 7.289089776186576, "LEVODOPA": 19.5775776476232, "LURASIDONE": 35.31515533057852, "LYRICA": 2.0981410098091517, "NEUPRO": 27.76609363995252, "OLANZAPINE": 14.141258067707325, "PALIPERIDONE": 20.998724996593538, "PANTOPRAZOLE": 1.8187206460082253, "PEGASYS": 1.6524815722865702, "PEGINTRON": 2.635276954199362, "SIFROL": 5.636504886584267, "STALEVO": 7.979028547149376, "SUBOXONE": 1.8292970788950649, "TAMIFLU": 14.63523803697848, "VFEND": 3.317644910641018, "VIMPAT": 2.5948779157056894, "XYREM": 5.735166811737682, "ZYPADHERA": 3.6048305583936657, "ZYPREXA": 8.217355103437207, "null": 2.129155449540047}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2301.json
index f75273f6fe6..04e5497bc00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2301.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2301.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 417.46826283698624, "CARIPRAZINE": 687.8930317540205, "OLANZAPINE": 18.813203501731092}
\ No newline at end of file
+{"null": 16.28693540177556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2302.json
index de94f4485e7..373180a97d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2302.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2302.json
@@ -1 +1 @@
-{"null": 1.388232084887758}
\ No newline at end of file
+{"ELIQUIS": 0.8068670504503201, "SPIRONOLACTONE": 11.757587920623507, "null": 16.3633263738666}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2303.json
index 34b51d53f88..10bd5738d99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2303.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2303.json
@@ -1 +1 @@
-{"null": 1.3693027734094874}
\ No newline at end of file
+{"ACLIDINIUM": 3.63159670714588, "ANGIOX": 21.47309423000936, "APIXABAN": 1.6387743863376685, "APROVEL": 2.2873306719462456, "ARANESP": 90.55428860315644, "ARIPIPRAZOLE": 0.6606398794285822, "AVANDAMET": 5.5947484536308805, "AVANDIA": 7.421890013339674, "BEDAQUILINE": 2.565180070042742, "BORTEZOMIB": 8.686976265927408, "BRILIQUE": 4.322600281455882, "BUDESONIDE": 0.313206458067563, "BUSILVEX": 15.663790544067131, "BYETTA": 0.5327381834801037, "CAELYX": 2.455242648088, "CAPECITABINE": 2.4619334589528603, "CARFILZOMIB": 3.7867386506532057, "CELLCEPT": 0.5407693662047848, "CICLOSPORIN": 0.723869577122937, "CLOPIDOGREL": 2.33130480540848, "COMIRNATY": 0.1912973929703613, "CYMBALTA": 0.1774279541064193, "CYTARABINE": 0.8170389901742117, "DARBEPOETIN": 89.32334810185446, "DEXAMETHASONE": 0.8910858990327885, "ELIQUIS": 0.8358149638752492, "ENTRESTO": 8.206561567190434, "ESOMEPRAZOLE": 2.056575136199732, "EXFORGE": 0.9612728375500958, "FENTANYL": 2.4683187020159587, "FLUTICASONE": 21.132713607207823, "FORSTEO": 0.4362430424574929, "GANCICLOVIR": 3.7547533692140367, "GLUCAGON": 33.14749217031573, "HUMAN": 2.341307167986012, "IBUPROFEN": 2.041106759695461, "INTEGRILIN": 27.601603830101084, "IPILIMUMAB": 1.768056157500764, "IRBESARTAN": 5.037826818911573, "JANUVIA": 0.5049899793050411, "JARDIANCE": 0.4618548695420491, "KEYTRUDA": 0.6874383910176546, "LEVEMIR": 0.7697300963915075, "LEVETIRACETAM": 0.8127111162373161, "LOXAPINE": 25.85309436914321, "MELATONIN": 5.566022150973088, "MICARDIS": 3.331409776282087, "MIDAZOLAM": 4.964785522051779, "OLANZAPINE": 0.7561019458876767, "OPDIVO": 0.7563961917738219, "OPSUMIT": 1.8792588204204217, "PEMBROLIZUMAB": 1.5971861754651926, "PLAVIX": 1.515516260715729, "PROPRANOLOL": 14.03840097043482, "REVATIO": 1.312983723945473, "ROACTEMRA": 1.1706854877544444, "SILDENAFIL": 5.4554555801865385, "SOLIRIS": 0.8258397494262799, "SPIKEVAX": 0.1995481060949998, "SUFENTANIL": 7.741719728053575, "SUTENT": 0.5710031942824979, "TICAGRELOR": 3.040671287583894, "TOZINAMERAN": 0.1103304978332208, "TRACLEER": 1.9143040743512565, "VALSARTAN": 4.632575611042719, "VAXZEVRIA": 0.072438836525714, "VIAGRA": 1.3035047666596773, "VOTRIENT": 1.112007744904621, "XARELTO": 1.3083644496482325, "null": 1.68726924689232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2304.json
index a61270d4b00..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2304.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2304.json
@@ -1 +1 @@
-{"OLANZAPINE": 120.23698780931264}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2305.json
index 822d9971c44..0edf5c2deca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2305.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2305.json
@@ -1 +1 @@
-{"ABILIFY": 152.4840657694575}
\ No newline at end of file
+{"null": 0.966937321188353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2306.json
index 0df69ee1cb1..c60fd612ae0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2306.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2306.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 16.97342171461172, "null": 2.20912144544718}
\ No newline at end of file
+{"ACTOS": 11.784102431181612, "ADCIRCA": 5.1029667003308985, "AFINITOR": 0.7910110142288437, "ARAVA": 0.1491948874556105, "ARIPIPRAZOLE": 3.3743917094776688, "AVANDAMET": 11.894069204386057, "AVANDIA": 13.114856039998877, "AVASTIN": 1.0808486570279066, "AZATHIOPRINE": 1.1734971886900711, "BOSENTAN": 12.802095898522364, "BOSULIF": 2.384336105720248, "BUDESONIDE": 0.5881390666443639, "BUMETANIDE": 27.86399905350964, "BUPRENORPHINE": 1.855496437741684, "BUSULFAN": 1.463747635752914, "BYETTA": 1.982124154245464, "CICLOSPORIN": 2.346850189356014, "CLOPIDOGREL": 0.8631708608410705, "COMIRNATY": 0.2547298360251285, "COSENTYX": 0.4633046383101246, "CYMBALTA": 1.059141940549723, "DAPAGLIFLOZIN": 20.67409226058214, "DASATINIB": 8.784198340264332, "DEXAMETHASONE": 2.0022235605852496, "DULOXETINE": 12.277160380018277, "ELIQUIS": 0.4196569517351757, "ENTRESTO": 3.8053994364115713, "ENVARSUS": 63.15613650567877, "EVISTA": 2.909241428022039, "EXFORGE": 2.3604090464674408, "EXJADE": 2.5713692830985493, "FENTANYL": 2.300716692109133, "FESOTERODINE": 78.21093456841346, "FULVESTRANT": 2.881062526536045, "HUMALOG": 0.3023045905913846, "HUMIRA": 0.8648519255981787, "HYDROCORTISONE": 2.5390179900667085, "IBRANCE": 0.3540570912648217, "IBUPROFEN": 2.1579729183478453, "INSULIN": 0.9573329993384664, "IRBESARTAN": 4.026338499462886, "JAKAVI": 0.8876245405714409, "JANUMET": 2.782908478496785, "JANUVIA": 2.2170918546334955, "KEYTRUDA": 0.5117917695343231, "LANTUS": 0.1989368675601742, "LEVETIRACETAM": 1.1208309688169862, "MELATONIN": 4.048754845800217, "MIDAZOLAM": 3.990310001811636, "NAGLAZYME": 2.968025056718841, "OLANZAPINE": 0.6308094063560467, "OMALIZUMAB": 0.765685144981309, "OPSUMIT": 1.475261776656291, "OPTIMARK": 1.6008587340066545, "PEGASYS": 1.1521302688836277, "PEGINTRON": 1.3008452995580486, "PLAVIX": 0.3166974427047865, "SILDENAFIL": 3.837060207415077, "SIMPONI": 0.4096157475395479, "SPIKEVAX": 0.4066670361147813, "SPIRONOLACTONE": 4.050939879640464, "SPRYCEL": 2.341395871867739, "SUBOXONE": 0.5381761004451064, "SUTENT": 0.2078221556659068, "TASIGNA": 2.980123762641798, "TOZINAMERAN": 0.840977052822327, "TRACLEER": 1.7263589688261134, "VALSARTAN": 4.300357683712462, "VAXZEVRIA": 0.1268626452105867, "VOTRIENT": 0.6384461724616438, "XELJANZ": 0.5478929078248107, "XOLAIR": 1.192191372907967, "ZOMETA": 18.884744779447683, "ZOSTAVAX": 1.2117432502348509, "ZYPREXA": 1.5845452607862287, "null": 1.5615624068030542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2307.json
index 54d258f919a..baf6091cb3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2307.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2307.json
@@ -1 +1 @@
-{"TOZINAMERAN": 1.6093976224199882, "null": 1.9483364471323248}
\ No newline at end of file
+{"ABILIFY": 0.7447647252222642, "AFINITOR": 0.9947092788398698, "AIMOVIG": 0.4542391890548253, "ALIMTA": 1.423812560959525, "APIXABAN": 0.7548768624932938, "ARAVA": 0.4236590907638801, "ARIPIPRAZOLE": 3.613159969537144, "ASENAPINE": 32.10236724451382, "ASPARAGINASE": 2.0773390698575485, "ATRIPLA": 0.086653358627546, "AUBAGIO": 0.7199576843948396, "AVANDAMET": 33.29832491463044, "AVANDIA": 25.77657123942545, "AVASTIN": 2.664804813306348, "AZACITIDINE": 4.3059031483059576, "BEDAQUILINE": 3.888876601667241, "BETAFERON": 4.149613964252412, "BUPRENORPHINE": 1.06338854292303, "BUSULFAN": 1.4442817134540458, "BYDUREON": 0.5757570505225386, "BYETTA": 1.391637711498337, "CELLCEPT": 1.244983612032191, "CICLOSPORIN": 0.3157719084470364, "COMIRNATY": 0.2996998059406467, "COTELLIC": 4.832497607997906, "CRIXIVAN": 6.105403076181301, "CYMBALTA": 0.5833330545076452, "CYTARABINE": 4.113149728952029, "DAPAGLIFLOZIN": 5.394555322726371, "DEXAMETHASONE": 0.6934049016610332, "DOCETAXEL": 3.410836650269024, "DOXORUBICIN": 7.85212425884016, "ELIQUIS": 0.8987436124300561, "ENBREL": 0.4369967048829491, "ENTRESTO": 7.454447152644716, "EPIVIR": 4.148974458859302, "EXJADE": 0.8566076180176129, "FENTANYL": 0.8199842141824502, "GARDASIL": 0.1896889744434861, "HERCEPTIN": 14.65855317058424, "HUMALOG": 0.305972545672518, "HUMIRA": 0.6428169034479267, "IBRANCE": 0.2915289462621894, "ICLUSIG": 3.5179272264288315, "INLYTA": 1.0715781895523273, "IRESSA": 1.3429727775583966, "JANUMET": 0.9270757809528732, "JANUVIA": 0.7687349226613647, "JARDIANCE": 0.9352504397473544, "KALETRA": 1.8533548624525849, "KEYTRUDA": 2.022811556109173, "KYPROLIS": 7.437395059637401, "LAMIVUDINE": 3.812885749307082, "LANTUS": 0.2696248770978178, "LENVIMA": 2.9012502879927835, "LEVOFLOXACIN": 0.6990322396309706, "MABTHERA": 4.673806257893796, "MANNITOL": 16.42023319680405, "MECASERMIN": 117.02464658818084, "MEKINIST": 3.502203014324529, "MELPHALAN": 4.745125392259742, "METHOTREXATE": 0.897826485175629, "NEXAVAR": 0.4454810296726186, "NPLATE": 1.9766164705184928, "OLANZAPINE": 4.1866104583831, "ONGLYZA": 16.35629485735435, "OPDIVO": 1.203056165982386, "OSIMERTINIB": 6.939818742311763, "PEGASYS": 1.186610208655684, "PEGINTRON": 2.1187359744430783, "PEMBROLIZUMAB": 1.102107048454792, "PLAVIX": 0.429230589485768, "RITUXIMAB": 2.340208310825517, "ROSIGLITAZONE": 18.6057005735506, "ROTATEQ": 1.39796679126847, "SIMPONI": 0.3857611278592909, "SOLIRIS": 1.5834476406567028, "SPIKEVAX": 0.2295111647085935, "SPRYCEL": 1.0826326342998465, "STELARA": 1.5212999976626695, "SUTENT": 1.6284332032857105, "TAGRISSO": 5.997049806132496, "TASIGNA": 0.9892707929138618, "TESTOSTERONE": 7.362062427575814, "TOZINAMERAN": 0.3465855823042346, "TRASTUZUMAB": 49.084121584695424, "VAXZEVRIA": 0.0709927429607227, "VFEND": 1.177487222024768, "VOTRIENT": 1.2799099212072862, "XELJANZ": 0.3793258560831971, "XOLAIR": 1.0262360677706754, "ZOSTAVAX": 0.9831989532391362, "ZYPREXA": 1.797414073805505, "null": 1.2521495636433244}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2308.json
index ad4dbd874f8..5c51d02cc58 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2308.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2308.json
@@ -1 +1 @@
-{"ABILIFY": 1.25773129883071, "APIDRA": 1.1130964378253458, "ARANESP": 1.0531740778927383, "BOSULIF": 2.154371009725012, "BRAFTOVI": 1.0262807571736938, "BYDUREON": 1.0977332149348564, "CLOPIDOGREL": 1.4497591545726976, "COMTAN": 3.33866622885214, "CYMBALTA": 1.5734516468710398, "DENOSUMAB": 10.379835404757944, "DESCOVY": 4.217723472858996, "DEXAMETHASONE": 1.0353269986196212, "EBIXA": 7.231702824859253, "ELIQUIS": 6.967471757484527, "ENTACAPONE": 5.7229377599229245, "ENTRESTO": 2.07362891943684, "ERLEADA": 2.9628039732118605, "ESBRIET": 1.1033987298571832, "EVENITY": 6.38362169263948, "EXFORGE": 1.293406225525235, "EYLEA": 2.505447124480729, "HUMALOG": 6.70026152103368, "IBRANCE": 4.1310356315150685, "INCRUSE": 2.224813248590635, "INLYTA": 1.269887337012651, "INSULIN": 2.494178632942804, "INTRONA": 3.0672261014682647, "IRESSA": 1.3122644525204152, "JANUMET": 2.130302524146682, "JANUVIA": 2.2594358235708087, "JARDIANCE": 4.728857955557423, "KEPPRA": 1.389858430259742, "LANTUS": 6.567545976733981, "LATUDA": 1.7699351534112164, "LEVEMIR": 3.502844074267552, "LEVODOPA": 3.374356363861173, "LYRICA": 2.385931706722768, "MEMANTINE": 8.75329344637986, "METFORMIN": 5.124658783209105, "MICARDIS": 2.3369754469001798, "MIMPARA": 3.6802490962045935, "NEULASTA": 2.8494642604634706, "NINLARO": 2.2700589236002946, "OFEV": 1.118734381250433, "OLANZAPINE": 1.2738655095564115, "OXYBUTYNIN": 4.540028859091814, "PEGINTRON": 1.19057388458583, "RANOLAZINE": 7.619257816376308, "RAPAMUNE": 2.856320574446203, "REVATIO": 1.7080667417827742, "RISPERIDONE": 2.26469208410736, "RUBRACA": 1.4352739684404845, "SIFROL": 3.323804362684906, "SIMPONI": 1.3911715433387777, "SPIRONOLACTONE": 5.34560661643054, "SPRYCEL": 1.4605457977744558, "STALEVO": 6.316883951515079, "TAGRISSO": 1.5407403166251616, "TOUJEO": 6.092282818276282, "TOVIAZ": 18.64045421702887, "TRELEGY": 3.376334451317821, "TRULICITY": 3.1000158853589075, "VIAGRA": 1.610345934815859, "VICTOZA": 1.385317358434905, "VIMPAT": 1.2663083623248164, "XALKORI": 1.2258049495080658, "XELJANZ": 2.927416845710002, "XTANDI": 4.215567406105599, "ZOSTAVAX": 1.0079167774511624, "ZYPREXA": 1.4485098244183972, "null": 1.5202527787555502}
\ No newline at end of file
+{"null": 1.1224458558320825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2309.json
index 2050c5e66b0..056e5b4282b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2309.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2309.json
@@ -1 +1 @@
-{"APIDRA": 1.6095846604726858, "BYETTA": 1.40351661247014, "CELECOXIB": 8.361621715817536, "CYMBALTA": 1.1647862389625008, "EBIXA": 17.77008851652304, "ELIQUIS": 5.524412585524457, "EPADERM": 309.6623483634038, "EXELON": 47.43302399078536, "EXFORGE": 1.998919395441053, "FORSTEO": 1.3999382461901684, "HUMALOG": 9.090033673300798, "IBRANCE": 2.773054846962712, "INSULIN": 2.6365960210117487, "IRON": 17.855250149778783, "JANUMET": 2.200807864547316, "JANUVIA": 1.174918637593046, "KEPPRA": 1.271650075363064, "LANTUS": 9.257957408696306, "LEVEMIR": 7.023380447787936, "MEMANTINE": 18.50834631317517, "TOVIAZ": 6.946127994218147, "TRELEGY": 2.3450147402492263, "TRULICITY": 3.838791649060912, "VIAGRA": 3.2188180739151204, "XELJANZ": 3.3009719354619595, "XTANDI": 2.241627140416161, "ZOSTAVAX": 1.280918602267526, "ZYPREXA": 1.9049713555489587, "null": 2.0523851731833904}
\ No newline at end of file
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/231.json
index 7cba1e9b60a..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/231.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/231.json
@@ -1 +1 @@
-{"BUDESONIDE": 12.03952252084461, "HYDROCORTISONE": 47.97235498325499, "IPILIMUMAB": 14.090822527498725, "KEYTRUDA": 16.494137195926907, "OPDIVO": 27.73348853346601, "TOZINAMERAN": 1.0845229618452783, "YERVOY": 21.3103035724141}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2310.json
index 2581112b8bf..1c93d877847 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2310.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2310.json
@@ -1 +1 @@
-{"OLANZAPINE": 26.069378498150364, "null": 1.2090259438920554}
\ No newline at end of file
+{"null": 1.174616373878293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2311.json
index 46b8279fe3b..499cb7a2ab4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2311.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2311.json
@@ -1 +1 @@
-{"CLADRIBINE": 2700.08201525175}
\ No newline at end of file
+{"AMINOSALICYLIC": 6.054997755175523, "AVANDIA": 5.294740101758958, "BEDAQUILINE": 41.90646033197992, "CELLCEPT": 2.2870583019735395, "CICLOSPORIN": 1.1762331920466196, "COMIRNATY": 0.1743384092220135, "DELAMANID": 18.20601560147, "FORSTEO": 1.8449885919185816, "LEVETIRACETAM": 3.732807184881615, "MIDAZOLAM": 4.795373189967204, "NEXAVAR": 1.1912100042153615, "OPSUMIT": 2.231243003460801, "PEGASYS": 0.5213149379948985, "SUTENT": 24.860420355800468, "TRACLEER": 11.494998527235657, "VAXZEVRIA": 0.0638150475131026, "null": 1.1362205156767804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2312.json
index 613ff231c31..312fe2b90f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2312.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2312.json
@@ -1 +1 @@
-{"ARAVA": 1.4331374742810823, "CICLOSPORIN": 3.55634035998865, "CIMZIA": 2.549368610741219, "KEYTRUDA": 2.563656516047594, "PEGASYS": 2.397865990226409, "SHINGRIX": 5.473951036233877, "SIMPONI": 3.41203970916565, "TOZINAMERAN": 1.018781868410386, "VAXZEVRIA": 1.1741235854574106}
\ No newline at end of file
+{"ENTRESTO": 48.39212622070965, "null": 0.8411798410663428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2313.json
index a0f23d950fb..ac34eff7261 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2313.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2313.json
@@ -1 +1 @@
-{"ARAVA": 1.953447902459249, "AUBAGIO": 3.1058833407848643, "CICLOSPORIN": 2.552343402121895, "CIMZIA": 2.281851597732297, "COSENTYX": 1.2756234826385526, "ENBREL": 2.676618414305116, "GARDASIL": 11.827197393323337, "HUMIRA": 9.925071282928124, "PEGINTRON": 1.94394604759672, "ROACTEMRA": 3.916072392354402, "SHINGRIX": 2.744088513231518, "SIMPONI": 19.00197816287733, "TOZINAMERAN": 1.0093584076614317, "TWINRIX": 7.087642895744789, "ZOSTAVAX": 1.623964324544903}
\ No newline at end of file
+{"APIXABAN": 1656.455825694076, "COMIRNATY": 0.114509519205878, "null": 0.1198242746782613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2314.json
index 29f941b7bbd..e1732fda192 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2314.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2314.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 9.010566589529642, "APIDRA": 7.023262360475538, "BENLYSTA": 28.03295257333437, "LANTUS": 1.880827034917833, "SIMPONI": 37.67464378196184, "STELARA": 7.110031173772447, "SUTENT": 1.5683548688104714}
\ No newline at end of file
+{"ABACAVIR": 92.33324993520672, "ADEMPAS": 259.63979882364947, "null": 1.2261299448485652}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2315.json
index b8ecb68120a..5121d8c47a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2315.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2315.json
@@ -1 +1 @@
-{"CICLOSPORIN": 51.84362451150208}
\ No newline at end of file
+{"ASPARAGINASE": 9.010791390349253, "AVAPRITINIB": 288.3915723392538, "AVASTIN": 2.4453535113826077, "BEVACIZUMAB": 4.402084406818741, "BORTEZOMIB": 6.771867693294144, "BUSULFAN": 5.147829648346741, "CAELYX": 20.606775732460548, "CAPECITABINE": 27.77345307059434, "CARFILZOMIB": 10.557828043198452, "CICLOSPORIN": 1.1530544644110563, "CYTARABINE": 8.865183445218223, "DEXAMETHASONE": 4.370467078995968, "DOCETAXEL": 21.50628019338558, "DOXORUBICIN": 21.588565504985556, "HERCEPTIN": 33.84908456206, "ICLUSIG": 4.4571784064512965, "KEPPRA": 0.7544317073395709, "KEYTRUDA": 1.9859511207917249, "KYPROLIS": 39.31032247622005, "LACOSAMIDE": 16.55230723782678, "MEKINIST": 4.197022043627395, "METHOTREXATE": 2.2124765301055302, "OLANZAPINE": 1.4281753857046504, "OSIMERTINIB": 26.771586678691445, "PACLITAXEL": 13.079300952149048, "PERTUZUMAB": 55.73073659640681, "RITUXIMAB": 2.811474792144245, "SUTENT": 2.1791008956185025, "TAGRISSO": 4.967330641045299, "TRASTUZUMAB": 131.50693862250031, "VOTRIENT": 6.360747088098486, "XELODA": 8.364532985830472, "null": 1.8938518209826352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2316.json
index cfe74809f7a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2316.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2316.json
@@ -1 +1 @@
-{"COMIRNATY": 6.732630193117614}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2317.json
index 43fd7b51fe6..efd817334fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2317.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2317.json
@@ -1 +1 @@
-{"ELIQUIS": 5.710555313068394, "IBRANCE": 11.220936108878467, "SIMPONI": 29.95925010173976}
\ No newline at end of file
+{"COMIRNATY": 5.006871380637122, "SPIKEVAX": 1.7295173117875402, "null": 0.3185677083960935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2318.json
index 2570da4d4f5..51889e4845d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2318.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2318.json
@@ -1 +1 @@
-{"APIXABAN": 1.1204787539368952, "ATRIPLA": 17.30665710542336, "AUBAGIO": 3.2887287314432165, "BIKTARVY": 2.6212489157039336, "BONVIVA": 6.639198397293432, "BUPRENORPHINE": 2.4035610381431987, "CIMZIA": 1.6433693728529617, "DESCOVY": 13.010340473531096, "ELIQUIS": 1.639443737184309, "ENBREL": 2.9782234198593858, "FASLODEX": 1.8288518786351589, "FORSTEO": 2.320237037927315, "HUMIRA": 1.7580267592814478, "METHOTREXATE": 1.3603557688355006, "PEGASYS": 2.095454291685986, "PEGINTRON": 1.2841151393740105, "RITUXIMAB": 2.65942640598749, "STELARA": 1.1144956604923957, "STRIBILD": 4.099300429734812, "SUBOXONE": 12.260898337107454, "TRUVADA": 4.4449558645243314, "ZYPREXA": 1.243258617317775, "null": 1.2445969401870622}
\ No newline at end of file
+{"ABILIFY": 0.5744624836087782, "ADALIMUMAB": 0.0462312517179172, "AIMOVIG": 0.7130170835380284, "APIDRA": 1.0024002159553862, "ARAVA": 0.0525893932539435, "ATRIPLA": 0.1029936789210699, "AVANDAMET": 34.3377536578613, "AVANDIA": 28.280664935486307, "BEDAQUILINE": 0.9303904266852052, "BONVIVA": 1.2422553795661844, "BYDUREON": 0.2932742604301501, "BYETTA": 0.3149048339026719, "CASPOFUNGIN": 1.7240311228780882, "CHAMPIX": 0.5897359790280118, "CICLOSPORIN": 0.1297600184687165, "CIMZIA": 0.12808679963921, "CLOPIDOGREL": 0.4357629869025975, "COMBIVIR": 1.2453847934344353, "COMIRNATY": 1.5785795078060878, "COSENTYX": 0.2134155483510533, "CYMBALTA": 0.2630439054883964, "DULOXETINE": 0.5215838571189052, "EDOXABAN": 14.055006195822392, "ELIQUIS": 0.6400316417587836, "ENTRESTO": 0.5052887696272308, "EVENITY": 1.1537551342621943, "EYLEA": 0.431186939437072, "FAMPYRA": 1.2878148719931364, "FASLODEX": 0.3021648153984775, "FORSTEO": 1.039483886681613, "FORXIGA": 0.6487640963370638, "GARDASIL": 0.2037720877367698, "HUMALOG": 0.4887812708957324, "IBRANCE": 0.177885731656705, "IBUPROFEN": 0.3824635863692643, "ICLUSIG": 2.010681025695614, "INSULIN": 0.5214035069821665, "JAKAVI": 0.708807634327346, "JANUMET": 0.5089648113074549, "JANUVIA": 0.2636144953679216, "JARDIANCE": 0.722754490019728, "KEPPRA": 0.1564567388991585, "KYPROLIS": 2.125939971835359, "LANTUS": 0.2940784991777221, "LEVOFLOXACIN": 1.1049522763135964, "MEKINIST": 0.4517593654898886, "NIMENRIX": 0.6083467886289909, "OLANZAPINE": 0.1961920634915763, "ONGLYZA": 56.45751122080873, "PEGASYS": 0.1173826982583414, "PEGINTRON": 0.2684511298098026, "PLAVIX": 0.7699604616699055, "RELVAR": 1.301615578350671, "RINVOQ": 0.722782099974917, "ROACTEMRA": 1.00321039339491, "ROSIGLITAZONE": 15.261591344174978, "SAXENDA": 0.4285787601243574, "SHINGRIX": 1.5347447057526902, "SIMPONI": 0.3047866216322153, "SOLIRIS": 0.2902516661824347, "SPIKEVAX": 0.973370826337092, "SPRYCEL": 0.3929103240539904, "STELARA": 0.4441975439065663, "SUTENT": 0.134529593015617, "TAMIFLU": 0.3375043115703828, "TASIGNA": 1.8899062532363544, "TOZINAMERAN": 0.1593809317356177, "TRULICITY": 0.4723537767057566, "TRUVADA": 0.061159727462008, "TWINRIX": 1.5123207947342203, "VAXZEVRIA": 0.7046740486861357, "VIAGRA": 1.271181861258729, "XELJANZ": 0.264815797933733, "XOLAIR": 0.4982259176631111, "XTANDI": 0.2589754655964457, "ZOSTAVAX": 0.6072084124754663, "ZYPREXA": 0.4156992827335802, "null": 1.539856486291002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2319.json
index 8a85e699591..6ed6d3e8c0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2319.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2319.json
@@ -1 +1 @@
-{"IBRANCE": 6.220108921870515, "SPIKEVAX": 1.0717687473855069, "null": 1.0661514878614582}
\ No newline at end of file
+{"OPSUMIT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/232.json
index 9fea7bd9f8b..dcbd8530449 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/232.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/232.json
@@ -1 +1 @@
-{"COMIRNATY": 3.870258053096293}
\ No newline at end of file
+{"FENTANYL": 140.18640990988268, "null": 1.1637784968729086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2320.json
index 7b1c82e12c2..7018662811b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2320.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2320.json
@@ -1 +1 @@
-{"null": 1.035751231955396}
\ No newline at end of file
+{"COMIRNATY": 0.5581857750031425, "CYMBALTA": 1.6072772978476004, "DEXAMETHASONE": 8.857730045138805, "ENTRESTO": 3.683105492181041, "JANUVIA": 2.7951852559606523, "MIDAZOLAM": 7.11276355366859, "OPSUMIT": 2.354962556986151, "RASBURICASE": 168.13610249659004, "ROACTEMRA": 9.13500907927468, "SPIKEVAX": 0.1881648066431227, "VAXZEVRIA": 0.2431483277523482, "null": 1.5215137682187347}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2321.json
index 1ec0e8c5560..6fcf3991f22 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2321.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2321.json
@@ -1 +1 @@
-{"ELIQUIS": 4.457816363781606, "IBRANCE": 5.71507430599807, "SIMPONI": 20.72078576147901, "XELJANZ": 6.622210238141171}
\ No newline at end of file
+{"COMIRNATY": 2.385426819025611, "SPIKEVAX": 1.946020579644117, "null": 0.50767180939712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2322.json
index 1b231b1bd96..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2322.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2322.json
@@ -1 +1 @@
-{"COMIRNATY": 1.788733381837704, "COVID19": 2.5200432444479546}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2323.json
index f845c797422..93af832fbfa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2323.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2323.json
@@ -1 +1 @@
-{"null": 2.1366854047680577}
\ No newline at end of file
+{"COMIRNATY": 0.1553361600471993, "ELIQUIS": 30.36365240530564, "OPSUMIT": 6.7311624215253865, "SILDENAFIL": 16.13786459601993, "SPIKEVAX": 0.7611620590983416, "TRACLEER": 5.413709178254137, "null": 1.5653982200133407}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2324.json
index 922bd2dce53..25b1c6831ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2324.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2324.json
@@ -1 +1 @@
-{"ATRIPLA": 41.02140207839055}
\ No newline at end of file
+{"COMIRNATY": 4.834917703594251, "SPIKEVAX": 1.8560048442095085, "TOZINAMERAN": 4.194988060949562, "null": 0.1563853038992392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2325.json
index 9491873afbc..41eaca7ac57 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2325.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2325.json
@@ -1 +1 @@
-{"ARAVA": 1.711848182816304, "FORSTEO": 11.498646097245176, "METHOTREXATE": 39.22088388840281, "PEGASYS": 4.119843891416878}
\ No newline at end of file
+{"COMIRNATY": 4.926492766638817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2326.json
index 9c6bd126e4c..9ec10b68b55 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2326.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2326.json
@@ -1 +1 @@
-{"null": 5.194688139804288}
\ No newline at end of file
+{"SHINGRIX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2327.json
index e4809b151e9..c3e5db8bb1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2327.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2327.json
@@ -1 +1 @@
-{"ABILIFY": 1.6713075976366034, "BUPRENORPHINE": 79.08272387997405, "CHAMPIX": 2.776768499441, "FENTANYL": 12.019595835912796, "LYRICA": 1.2695855685234363, "OMALIZUMAB": 1.836233402491368, "PEGINTRON": 1.312083573971311, "PREGABALIN": 4.957490411327145, "SIFROL": 19.03212372873904, "SUBOXONE": 8.948206636483034, "null": 5.894619681387182}
\ No newline at end of file
+{"null": 2.1368762975438496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2328.json
index f21139de3c3..2cc6f17c870 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2328.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2328.json
@@ -1 +1 @@
-{"OPSUMIT": 17.24145250144739}
\ No newline at end of file
+{"null": 4.195177714389095}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2329.json
index 4c2bfa22c4b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2329.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2329.json
@@ -1 +1 @@
-{"null": 1.999426350398048}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/233.json
index c5765a64ae0..f61c5605268 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/233.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/233.json
@@ -1 +1 @@
-{"IPILIMUMAB": 68.06164462891408, "KEYTRUDA": 104.73329088046238, "OPDIVO": 314.68175790908253, "PEMBROLIZUMAB": 26.99864727474692}
\ No newline at end of file
+{"CYTARABINE": 13.900643101419472, "DOCETAXEL": 10.780904969572008, "DOXORUBICIN": 22.85371684936645, "PACLITAXEL": 34.86832352491992, "RADIATION": 1435.2248209618683, "THIOTEPA": 80.76217224837043, "null": 2.025941640663986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2330.json
index 6ea2f18d565..b4fdba9c321 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2330.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2330.json
@@ -1 +1 @@
-{"BRINTELLIX": 12.237684036519497, "CELECOXIB": 13.375895333531496, "CHAMPIX": 6.006566643859938, "CYMBALTA": 1.9276451126513616, "KEPPRA": 3.327241618698468, "ZYPREXA": 1.5365665858817013, "null": 3.5295148955274684}
\ No newline at end of file
+{"ACLIDINIUM": 69.48812564852915, "BIKTARVY": 30.269188311999528, "CLOPIDOGREL": 5.109050105697414, "COMIRNATY": 0.1503969114687224, "ELIQUIS": 2.513248020542885, "ICLUSIG": 47.80376620813438, "TASIGNA": 34.8886891616689, "ZOSTAVAX": 4.153763174746904, "null": 0.6739671777347038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2331.json
index c546f06fa8f..499088ef347 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2331.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2331.json
@@ -1 +1 @@
-{"null": 2.356026082357269}
\ No newline at end of file
+{"COMIRNATY": 0.5318900205087971, "null": 0.6850805533046944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2332.json
index 7f5b9973c24..828583c83a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2332.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2332.json
@@ -1 +1 @@
-{"null": 2.778568784081628}
\ No newline at end of file
+{"AVANDAMET": 34.88417120150129, "AVANDIA": 32.31122725560829, "COMIRNATY": 0.1276317863988081, "ELIQUIS": 4.373784406262022, "TASIGNA": 12.28187439221012, "VIAGRA": 12.715402064002356, "ZOSTAVAX": 7.161578420447696, "null": 1.0922809367520905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2333.json
index 47a17cd2322..845852729cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2333.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2333.json
@@ -1 +1 @@
-{"null": 1.3959986505165196}
\ No newline at end of file
+{"COMIRNATY": 3.015917268956335, "SPIKEVAX": 0.6901176719062457, "VAXZEVRIA": 0.4286185448852804, "null": 0.7788198729291457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2334.json
index a1d03f9491e..2bac41d6f24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2334.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2334.json
@@ -1 +1 @@
-{"ABILIFY": 2.198927377811663, "ACTOS": 3.0322508710405143, "ACTRAPID": 1.5936359004438467, "ALOXI": 5.137880036911207, "AMBROXOL": 53.033409088262985, "AMIKACIN": 1.1165156222196395, "AMLODIPINE": 44.3927610565479, "APIDRA": 1.615177614445748, "ARIPIPRAZOLE": 1.301151819080612, "AZILECT": 2.5234116562268456, "BENZODIAZEPINE": 3.036433457461556, "BEXSERO": 1.1925695070988418, "BLINATUMOMAB": 2.576851147746055, "BRIDION": 3.628068049070933, "BUPIVACAINE": 3.588037867947536, "BUPRENORPHINE": 3.764046151100724, "CAFFEINE": 31.955032084904374, "CANCIDAS": 1.1201917586575922, "CIRCADIN": 1.6439613223681582, "COMTAN": 2.199421167886222, "DESLORATADINE": 1.548576943225752, "DOLUTEGRAVIR": 3.4339370663475286, "DULOXETINE": 2.8919819898296577, "EBIXA": 2.954448195420037, "ENTACAPONE": 2.157269882727704, "EPIVIR": 1.4260976224093815, "FENTANYL": 3.888916619398965, "FYCOMPA": 1.9210446704802908, "GANCICLOVIR": 3.6070946670252138, "GLIBENCLAMIDE": 2.483960358131197, "GLIVEC": 1.0455399202476623, "IBUPROFEN": 2.908909606249489, "IMATINIB": 1.889568216788012, "INSULIN": 1.3946614667024018, "INTEGRILIN": 2.8342548527553384, "KEPPRA": 1.1195986479329056, "LACOSAMIDE": 1.2274624245132395, "LANTUS": 1.4038560441986498, "LEVETIRACETAM": 1.3980483716374668, "LEVOFLOXACIN": 14.044451354883655, "LYRICA": 3.1514821741942813, "MELATONIN": 5.899756520856015, "METFORMIN": 1.244875669765376, "MICARDIS": 1.7933244613872128, "MIDAZOLAM": 6.009667076279464, "NALOXONE": 14.175203049477204, "NOT": 1.1574770492176474, "NOVONORM": 1.349224002781573, "OLANZAPINE": 4.707869162000302, "PREGABALIN": 7.885692769161086, "PREVENAR": 1.157227404769575, "PROPRANOLOL": 2.35175437552844, "REPAGLINIDE": 3.56984247287949, "RISPERIDONE": 14.849125585452851, "SIFROL": 1.010931396540441, "SOVALDI": 1.309782949333235, "STALEVO": 1.8394071627521311, "STIVARGA": 1.406401109599266, "SUFENTANIL": 1.8437764409201869, "TAMIFLU": 2.425376970611416, "TEDUGLUTIDE": 7.300647887370133, "TIVICAY": 1.3848559043199034, "VECTIBIX": 1.4676872374149044, "VFEND": 1.385340637482282, "VIMPAT": 1.939178852860028, "VORICONAZOLE": 1.4163913556281365, "XYREM": 5.4372118707299295, "YESCARTA": 2.747902572659217, "ZONISAMIDE": 5.605950268983202, "ZYPADHERA": 6.974873881044728, "ZYPREXA": 2.901233265934018, "null": 2.487718266299383}
\ No newline at end of file
+{"APIXABAN": 136.0551387464494, "AVANDIA": 5.520725541068261, "BYDUREON": 3.0418654786908625, "CLOPIDOGREL": 2.512361572746627, "COMIRNATY": 0.1936055216466339, "ELIQUIS": 2.296774839846297, "HUMALOG": 5.609933666985889, "LANTUS": 2.0809819483096037, "PLAVIX": 7.948095106370769, "SPIKEVAX": 0.2458711397353635, "TASIGNA": 12.772053013832174, "VAXZEVRIA": 0.1268151815064923, "ZOSTAVAX": 2.32775780849989, "null": 0.8884992367440974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2335.json
index c5b2eb6f64d..3d6314a4ed7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2335.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2335.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.032023338163597, "ABILIFY": 1.7369084301228177, "AERIUS": 1.8048800091986508, "AIMOVIG": 1.3664920880845577, "ALDARA": 1.4729059354181546, "ALISKIREN": 8.57322193773132, "ARIPIPRAZOLE": 2.12479692217687, "AUBAGIO": 3.7679125976158434, "BENLYSTA": 1.5960400424154348, "BETAFERON": 2.510332754822995, "BIKTARVY": 2.037233620709862, "BRINTELLIX": 4.078491582845115, "BRIVARACETAM": 5.250185683210288, "BRIVIACT": 4.787762008082611, "CABOTEGRAVIR": 5.646975128061232, "CARBIDOPA": 7.659685820049332, "CARIPRAZINE": 10.236132009041684, "CHAMPIX": 30.89667921573522, "CIRCADIN": 2.291865086084391, "COMTAN": 1.6373312317215252, "CYMBALTA": 2.3469999876754817, "DESLORATADINE": 2.7432208911221894, "DULOXETINE": 2.527195440901173, "ELLAONE": 2.4627070456965297, "EMTRICITABINE": 1.1636456121813792, "EVRA": 1.4655935978372965, "FAMPYRA": 1.7128433434203552, "FENTANYL": 1.6768855474145714, "FORSTEO": 1.9675398079431392, "FYCOMPA": 3.606328785464148, "GALAFOLD": 2.050213171226122, "GLYCOPYRRONIUM": 18.15735935340084, "IBRANCE": 1.4142073184591166, "INCIVO": 1.9102786685987732, "INSULIN": 2.7271226463845624, "INVEGA": 2.52863582089115, "KAFTRIO": 8.44636609018098, "KEPPRA": 3.077721966448562, "LACOSAMIDE": 2.986347093768269, "LATUDA": 4.72369524387399, "LEVETIRACETAM": 2.294681625794916, "LEVODOPA": 2.7511959485787765, "LURASIDONE": 5.137454208885906, "MELATONIN": 1.1978214709626078, "MEPOLIZUMAB": 2.129759083012056, "NORVIR": 1.4558456731858551, "OCRELIZUMAB": 3.943279236267077, "OLANZAPINE": 1.8651466153683451, "ORKAMBI": 1.6517092431932066, "OXYBUTYNIN": 1.5475661963129903, "PANTOPRAZOLE": 1.6834267627725494, "PEGINTERFERON": 1.8703959660647655, "PEGINTRON": 1.2572900651191, "PLEGRIDY": 3.595955988914513, "RISPERIDONE": 1.3184524799829105, "RYEQO": 7.165686182664994, "SAXENDA": 2.299246972206367, "TERIFLUNOMIDE": 3.6773538294595913, "TIVICAY": 3.033685811126822, "TRIUMEQ": 4.915513682832467, "VARENICLINE": 14.701112476663232, "XELJANZ": 1.895510590627439, "XYREM": 1.646129885448804, "null": 1.3591270122079098}
\ No newline at end of file
+{"ARANESP": 3.0388810680449785, "ARAVA": 0.5292167014439978, "AVANDIA": 21.873323527850555, "CANNABIDIOL": 58.28750891002685, "CLOPIDOGREL": 3.112290847149416, "COMIRNATY": 0.2219180999867431, "ELIQUIS": 3.152116899545741, "ENTRESTO": 1.9875924236454927, "EYLEA": 4.319689214498798, "FORSTEO": 2.284131476835194, "ICLUSIG": 18.05575825649166, "JARDIANCE": 2.0473496169051035, "KALETRA": 5.31877870624355, "NILOTINIB": 48.48881012128784, "OPTIMARK": 4.771383072175496, "PLAVIX": 2.026181181131145, "SILDENAFIL": 8.651526466993742, "SPIKEVAX": 0.189769061723365, "TASIGNA": 73.37185286760841, "VAXZEVRIA": 0.0718931091424103, "ZOSTAVAX": 8.228797045675305, "null": 0.7908836858913918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2336.json
index 1a66ac19d32..115c7017e03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2336.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2336.json
@@ -1 +1 @@
-{"ABATACEPT": 2.2616518827066425, "ABILIFY": 2.8090712789857384, "ACETAMINOPHEN/OXYCODONE": 4.811151319976349, "ADALIMUMAB": 2.139216839547317, "AGOMELATINE": 7.246560925543954, "AIMOVIG": 1.5898206463952718, "ALDARA": 1.5456304821662965, "ALENDRONATE": 7.249656867443968, "ALL": 2.4672795991243306, "ALLI": 3.773920480370724, "AMPRENAVIR": 5.2904288142913645, "ARIPIPRAZOLE": 1.4867455055308088, "ARSENIC": 3.504193887030684, "ATAZANAVIR": 16.76957930501159, "ATEZOLIZUMAB": 1.047416079799519, "ATRIPLA": 1.880431740413681, "AUBAGIO": 3.0684068449610264, "AVANDAMET": 1.3109856708276542, "AVANDIA": 1.0245791321934898, "AVONEX": 3.461567957069028, "AZILECT": 1.5627267041944393, "BENLYSTA": 2.1400587771739827, "BETAFERON": 3.182238101549189, "BEXTRA": 1.9157122850209027, "BIKTARVY": 3.8598489202733943, "BOCEPREVIR": 4.013447813294661, "BRINTELLIX": 2.447345912842502, "BRIVARACETAM": 3.860691487296666, "BRIVIACT": 4.602895454458997, "BUPIVACAINE": 1.494064048895675, "BUPRENORPHINE": 2.8313104439772623, "BYETTA": 1.2678256546848918, "CABOTEGRAVIR": 1.5808567552708643, "CANAGLIFLOZIN": 9.045427258831229, "CANNABIDIOL": 2.024009624465931, "CELECOXIB": 1.5207392078501092, "CELSENTRI": 2.146823113076952, "CHAMPIX": 17.582043903074794, "CIALIS": 6.547807783288016, "CIRCADIN": 1.068020957752076, "COMBIVIR": 1.8575670269211215, "COMTAN": 1.0974418734590594, "CONTRAST": 1.203285819614366, "CYMBALTA": 3.011128459136075, "DABRAFENIB": 1.187237075832743, "DAKLINZA": 1.9079636910281852, "DELTYBA": 3.2789827227433053, "DENOSUMAB": 2.2608074892830814, "DESCOVY": 1.6130158471764038, "DESLORATADINE": 1.3872994769321931, "DULOXETINE": 2.5895801890195767, "DUPIXENT": 1.127436314689923, "EDURANT": 3.063189597258597, "EFAVIRENZ": 1.0495182649144192, "EMTRICITABINE": 1.082340743728846, "ENBREL": 1.2621626030396078, "ENTACAPONE": 1.648450301071412, "EPCLUSA": 1.085450654092461, "EPIVIR": 1.006319918160559, "ESBRIET": 1.2061797663677545, "ESOMEPRAZOLE": 1.3207168282308284, "EVRA": 1.6375657539731474, "EXELON": 1.0867289097551582, "EXVIERA": 1.4332219356872464, "FASLODEX": 1.0520198321222922, "FORSTEO": 2.347216914815383, "FYCOMPA": 2.5250618784263463, "GALAFOLD": 2.416578072400478, "GARDASIL": 1.075229604856896, "GENVOYA": 1.486441212904592, "GILENYA": 1.4436964724699015, "GLYCOPYRRONIUM": 1.252252022134309, "HARVONI": 1.0892568039581407, "HUMIRA": 1.2765346968681015, "HYDROCORTISONE": 1.4886788683250642, "INCIVO": 3.332999509911333, "INFERGEN": 5.808101471663663, "INTELENCE": 1.5352375011015156, "INTERFERON": 4.6108796678941, "INTRONA": 7.497346323178047, "ISENTRESS": 2.0639384723199274, "IVABRADINE": 1.671382747592457, "JANUMET": 1.4061690399415157, "JANUVIA": 1.3730353502983916, "KAFTRIO": 3.9648397358436087, "KARVEA": 1.1617739371580025, "KEPPRA": 4.356320755418045, "KUVAN": 4.440819536219736, "LATUDA": 5.1761089234389415, "LEVETIRACETAM": 2.1160099814550777, "LEVODOPA": 2.9537147464829743, "LURASIDONE": 1.1818694090516, "LYRICA": 2.419153073669097, "METFORMIN": 1.2743410386674408, "MOVYMIA": 1.6881950946243325, "NORVIR": 1.1465176494861131, "NOT": 1.3201871992600476, "OCEAN": 6.944386209982682, "OCRELIZUMAB": 2.663208415682806, "OLANZAPINE": 1.402350192848997, "OLYSIO": 1.2478254148145205, "OPTIMARK": 2.185588670295014, "ORKAMBI": 1.0729124009900068, "OXYBUTYNIN": 1.3868318204690324, "OZEMPIC": 2.1263734495965623, "PALIPERIDONE": 3.146461521521919, "PEGASYS": 6.374490651132759, "PEGINTERFERON": 4.292448384359702, "PEGINTRON": 4.686396471036185, "PLEGRIDY": 2.042579728845687, "PROLIA": 1.3171038373552275, "PROPRANOLOL": 1.6005533631025768, "REBETOL": 3.4147703611952034, "REBIF": 1.7121680496983345, "REKAMBYS": 2.248412034285012, "RIBAVIRIN": 2.288724542443676, "RILUTEK": 1.5240296012094607, "RISPERIDONE": 1.7282109749003585, "RYEQO": 3.658163558345122, "SAXENDA": 1.821415833043064, "SEEBRI": 2.6814969961020743, "SEMAGLUTIDE": 1.9920282150253972, "SERTRALINE": 8.940130051093895, "SIFROL": 2.206091542051284, "SIRTURO": 1.5118427008821596, "SOFOSBUVIR": 1.5970215104039374, "SOVALDI": 2.201360839632474, "STALEVO": 1.856951956854812, "STELARA": 1.5431708713278265, "STRIBILD": 2.185897463030438, "SUBOXONE": 2.891214143922844, "SUSTIVA": 4.237372718495712, "SYCREST": 1.5326775343131014, "SYMTUZA": 1.7955971648500788, "TECFIDERA": 1.3878846754559375, "TEDUGLUTIDE": 2.2494264745268424, "TERIFLUNOMIDE": 1.275922317338876, "TESTOSTERONE": 1.3253821763893812, "TIVICAY": 2.839720441796729, "TRIUMEQ": 6.555983005847929, "TRUVADA": 1.3431797446599525, "TYSABRI": 2.1450639516135945, "VALDOXAN": 3.380313793476107, "VARENICLINE": 5.596001388417595, "VIAGRA": 1.6287567015732234, "VIMPAT": 2.169498110922961, "VIREAD": 1.228593321090685, "VORTIOXETINE": 3.577928223883628, "WAKIX": 3.248671775367829, "XYREM": 5.542094687141068, "ZEPATIER": 2.4235263320194136, "ZINBRYTA": 1.6681422531151913, "ZONISAMIDE": 1.862080840296376, "ZOSTAVAX": 3.627693464314411, "ZYPREXA": 1.8420502264388328, "null": 1.4122853853836257}
\ No newline at end of file
+{"null": 0.5347424042529709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2337.json
index 553400c63fe..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2337.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2337.json
@@ -1 +1 @@
-{"AIMOVIG": 2.5191300588259784, "ARIPIPRAZOLE": 2.754034204856714, "ATAZANAVIR": 440.8795870909281, "CHAMPIX": 20.72917340619236, "CYMBALTA": 2.578171696209027, "ENFUVIRTIDE": 188.32462309535268, "KEPPRA": 1.1278564814043284, "SAXENDA": 4.852419087068935, "ZYPREXA": 1.497441968738654, "null": 1.1975445382833785}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2338.json
index 40b78041755..1eb2bf52db5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2338.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2338.json
@@ -1 +1 @@
-{"ABACAVIR": 2.340914897702409, "ABILIFY": 3.2467226465185983, "AMIKACIN": 9.404026951051693, "ARIPIPRAZOLE": 2.8521885842704187, "ATAZANAVIR": 237.3642493336832, "BRINTELLIX": 6.700927110910641, "CHAMPIX": 19.49443370841311, "COMBIVIR": 3.140711009756534, "CYMBALTA": 2.208728030161121, "DULOXETINE": 5.465659993620178, "ENFUVIRTIDE": 112.08186894398936, "EPIVIR": 7.813857619497842, "INSULIN": 20.04622772029776, "INTRONA": 15.879332119412894, "ISENTRESS": 11.597591479885814, "KEPPRA": 2.3302092122696227, "LATUDA": 8.108743596904244, "LEVETIRACETAM": 2.2593546973045444, "MEPOLIZUMAB": 5.880628147294402, "NUCALA": 2.385547425297526, "OLANZAPINE": 2.476345667833245, "PEGASYS": 2.622464177618415, "PEGINTRON": 18.02828028460847, "RIBAVIRIN": 4.092827579778238, "SAXENDA": 5.487649066973128, "ZYPREXA": 2.4368056075384312}
\ No newline at end of file
+{"ALISKIREN": 1760.099041594252, "COMIRNATY": 0.3577626641291814, "SPIKEVAX": 0.2778475519096315, "VAXZEVRIA": 0.9861662115006156, "null": 0.4192618748389135}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2339.json
index 043d5ef1057..f6147c2ebb2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2339.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2339.json
@@ -1 +1 @@
-{"ABILIFY": 2.789014043641911, "BRINTELLIX": 26.29518250904418, "CHAMPIX": 11.78000862654678, "GARDASIL": 2.5345590122725574, "OLANZAPINE": 2.692353059626565, "null": 2.444646997154896}
\ No newline at end of file
+{"ZOSTAVAX": 19.785387955494038, "null": 2.0010543200712188}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/234.json
index b70d93f01e2..5d3f54e58c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/234.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/234.json
@@ -1 +1 @@
-{"COMBIVIR": 240.005173795878}
\ No newline at end of file
+{"ATRIPLA": 0.3519846065316347, "CHAMPIX": 8.98584171860406, "COMIRNATY": 0.0614264819752561, "CYMBALTA": 1.0186593089061924, "KEPPRA": 9.311174072780108, "LEVETIRACETAM": 12.312738919978113, "LEVOFLOXACIN": 4.078015921779758, "OLANZAPINE": 5.764954605499914, "PEGASYS": 3.270185807663208, "PEGINTRON": 5.606059565663121, "RISPERIDONE": 17.990680499979902, "VAXZEVRIA": 0.0627626800729366, "ZYPREXA": 5.174574349681914, "null": 1.8984875005325212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2340.json
index 6155c3a27b1..8023dac8356 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2340.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2340.json
@@ -1 +1 @@
-{"null": 1.9014649402371044}
\ No newline at end of file
+{"null": 0.8071462026075795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2341.json
index 6211486921e..fa63acb3950 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2341.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2341.json
@@ -1 +1 @@
-{"null": 9.529860179479076}
\ No newline at end of file
+{"null": 1.3183814393892817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2342.json
index 23ac9257383..16741313603 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2342.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2342.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 12.284136550451947, "ELIQUIS": 1.6011176529295696, "GARDASIL": 2.9716137295692797, "NEXAVAR": 4.526140502652323, "PEGASYS": 2.4183025313187896, "ZOSTAVAX": 5.70329922960105}
\ No newline at end of file
+{"COMIRNATY": 3.753871350688856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2343.json
index 433e29019c3..696224926ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2343.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2343.json
@@ -1 +1 @@
-{"COMIRNATY": 2.556611710984971, "SPIKEVAX": 8.075601187856439}
\ No newline at end of file
+{"FENTANYL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2344.json
index 1521e380307..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2344.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2344.json
@@ -1 +1 @@
-{"null": 1.768819331899959}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2345.json
index 65fc1b268df..7aefa1593b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2345.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2345.json
@@ -1 +1 @@
-{"null": 2.0186452439690656}
\ No newline at end of file
+{"JANUMET": 21.716820710747296, "JANUVIA": 43.69653346331915, "LANTUS": 7.631678656191119, "ZOSTAVAX": 8.205662689952828, "null": 0.8986094291332324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2346.json
index a80c35722b0..6df6790140c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2346.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2346.json
@@ -1 +1 @@
-{"ALDARA": 8.273588094486662, "ALIMTA": 3.381060798117484, "AMIKACIN": 2.127572083275284, "AZATHIOPRINE": 1.9163981350974808, "BIKTARVY": 7.073607594804571, "BRAFTOVI": 1.060525483178376, "BUSULFAN": 1.3763718160760152, "CAELYX": 3.7221453986412527, "CETUXIMAB": 7.4469670360214515, "CLOPIDOGREL": 1.466780741197683, "COSENTYX": 1.8204410644875864, "COTELLIC": 4.807930120966674, "ENBREL": 1.1904978428675157, "ERBITUX": 3.516965042932214, "ERLEADA": 1.9857858046984156, "ESBRIET": 1.3195437035732258, "FASLODEX": 1.0198107678721526, "FORXIGA": 1.0456326861710583, "HYDROCORTISONE": 2.944932120808041, "ICLUSIG": 1.839901937206452, "INCIVO": 4.769012724621072, "IPILIMUMAB": 5.698068196672309, "IRESSA": 6.059886490125115, "KEYTRUDA": 2.1926421512042102, "LEVOFLOXACIN": 2.5236922347929607, "LIXIANA": 1.4571304937385312, "METFORMIN": 6.074622979168644, "MIRVASO": 22.39980999291057, "NEXAVAR": 3.474828196584517, "NOT": 1.407899097039418, "OPDIVO": 4.015389865251529, "OPTIMARK": 3.329213697806414, "PEGASYS": 2.3261861166993985, "PEGINTERFERON": 2.5641203226093623, "PEGINTRON": 1.7955619462183123, "PEMBROLIZUMAB": 3.59109310304366, "PEMETREXED": 1.8996091057784348, "RIBAVIRIN": 3.1163940801727037, "RINVOQ": 1.5649163143480262, "STELARA": 1.3625570740040656, "STIVARGA": 1.321588789115982, "TAGRISSO": 3.846071887202495, "TEMOZOLOMIDE": 3.529005135167269, "TIVICAY": 4.247386074521855, "TRAMETINIB": 18.485370912065417, "VECTIBIX": 7.497178450670846, "YERVOY": 2.7729989938775077, "ZELBORAF": 2.22722579073258, "ZOSTAVAX": 3.626117179895468, "null": 1.5069202037861322}
\ No newline at end of file
+{"ABATACEPT": 0.5774714464773589, "ACLASTA": 30.76741645086172, "ADALIMUMAB": 0.2321982859332122, "APIXABAN": 91.26460706939746, "ARAVA": 0.7565139680761203, "ATRIPLA": 0.1539881393028645, "AUBAGIO": 6.670900422854494, "AVONEX": 16.64895637450029, "BYDUREON": 2.458792537481169, "BYETTA": 2.909981130563528, "CICLOSPORIN": 1.1389619766220578, "CIMZIA": 2.580462338797691, "COMIRNATY": 0.2684331965198911, "CYMBALTA": 0.8422425871787014, "DULOXETINE": 6.565924875689567, "ELIQUIS": 4.058968681583066, "ENBREL": 7.302437944713624, "ESOMEPRAZOLE": 4.558615165557465, "EXFORGE": 1.381296151897069, "FASLODEX": 2.2254393770234486, "GARDASIL": 0.8100558239906686, "HUMALOG": 4.592916441336316, "HUMIRA": 3.2532401238341717, "IBRANCE": 0.6731624867380392, "JANUMET": 1.268020350283954, "KEYTRUDA": 0.6298752332332327, "LANTUS": 2.3043445127288296, "LYRICA": 1.431869942687756, "METHOTREXATE": 1.7000643160379825, "NAGLAZYME": 14.148462967139364, "OCEAN": 134.7226658250234, "OMALIZUMAB": 2.730198339044233, "PEGASYS": 0.6400875184369132, "PEMBROLIZUMAB": 1.72885214850529, "SHINGRIX": 0.7803255817256113, "SIMPONI": 3.7606608607684446, "SPIKEVAX": 0.15810711579043, "STELARA": 1.2917564845452896, "SUBOXONE": 1.195783198277054, "TOZINAMERAN": 0.7380713396631117, "TREMFYA": 2.3578869659440174, "TRUVADA": 0.2644553327593019, "VAXZEVRIA": 0.1531803379686015, "XELJANZ": 4.703440015597934, "ZOSTAVAX": 8.274002839591528, "ZYPREXA": 0.4612184993313835, "null": 0.6621432776237437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2347.json
index 6d60f1ab5bc..0d6da5d0fd7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2347.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2347.json
@@ -1 +1 @@
-{"AFINITOR": 2.122595009066924, "AVASTIN": 3.6640948258434687, "AZATHIOPRINE": 3.676450076340119, "BEVACIZUMAB": 7.312747425755135, "BRAFTOVI": 35.456894439896715, "CABOMETYX": 5.175131553341047, "CETUXIMAB": 121.15455861306222, "COBIMETINIB": 48.64992690740817, "COTELLIC": 62.81203508210757, "DABRAFENIB": 14.005125160685402, "ERBITUX": 101.74043409911827, "GEFITINIB": 51.80496949539893, "HERCEPTIN": 4.6161009540491165, "IRESSA": 54.42788815540443, "IRINOTECAN": 29.70039445224959, "KAFTRIO": 13.767655817524668, "KEYTRUDA": 1.1804971987947837, "MEKINIST": 17.89565332767047, "NEXAVAR": 2.313862545664453, "PANITUMUMAB": 252.1960532479539, "RINVOQ": 12.996695656558094, "TAGRISSO": 23.26756462073814, "TARCEVA": 109.56520027175364, "TRAMETINIB": 178.3444788149086, "VECTIBIX": 447.14163840948726, "ZELBORAF": 8.024928535082667}
\ No newline at end of file
+{"null": 0.6906596195891206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2348.json
index bec602bb8a8..5bbbedf82df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2348.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2348.json
@@ -1 +1 @@
-{"ACTRAPID": 2.4796739850653986, "ARIXTRA": 5.038670178741249, "BENLYSTA": 1.066448622259526, "BRILIQUE": 1.2351521324173296, "CHAMPIX": 1.129610065036204, "CLOPIDOGREL": 1.2352638160439824, "COTELLIC": 3.560205889772776, "ENBREL": 4.674872070874673, "ENOXAPARIN": 1.640331428895484, "ERLEADA": 2.5803450660117644, "FIASP": 2.4324985569331963, "FLUTICASONE": 5.730631207715992, "ICLUSIG": 1.2742156896008283, "INCIVO": 1.041274505262311, "INSUMAN": 8.394612998488647, "JANUVIA": 1.1297561657207404, "KAFTRIO": 2.987810390436469, "LACOSAMIDE": 3.1859877651811277, "LEMTRADA": 1.2898315967103575, "LEVEMIR": 2.033118901061256, "LEVETIRACETAM": 2.295182024544755, "LEVOFLOXACIN": 2.447716675410443, "LIXIANA": 2.287985239180357, "MEPOLIZUMAB": 5.754657507771337, "MIDAZOLAM": 3.1203076095173974, "MMRVAXPRO": 1.620775716179209, "NEXAVAR": 1.2114852957987965, "NIMENRIX": 1.0886022792345138, "NUCALA": 1.884055101528552, "ONCASPAR": 2.3680730845568143, "PLEGRIDY": 1.1331970362926982, "PRIVIGEN": 3.23224443753568, "ROTATEQ": 1.7081849868130443, "SAXENDA": 1.9039949732014063, "SIMPONI": 1.3449436334628284, "TAMIFLU": 2.201679330322688, "TICAGRELOR": 1.5714380874033682, "TOUJEO": 1.30619119238236, "TRIUMEQ": 3.777233281008909, "TWINRIX": 2.642929518840741, "VIMPAT": 1.4639058767305673, "ZYPREXA": 1.0602716848788756, "null": 2.0055263816926483}
\ No newline at end of file
+{"COMIRNATY": 0.0872673322533058, "ENBREL": 5.073506918295278, "LANTUS": 3.403464685723955, "TRUVADA": 1.9607274937648935, "XELJANZ": 4.888742459165624, "null": 1.2316385438586936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2349.json
index 6ed3f85ebbd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2349.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2349.json
@@ -1 +1 @@
-{"ACLIDINIUM": 92.34949312126048, "ARIPIPRAZOLE": 7.039105799948315, "CICLOSPORIN": 3.684787954937666, "COMIRNATY": 1.056601831898042, "COSENTYX": 2.191661171766386, "DUPILUMAB": 151.26746399987078, "DUPIXENT": 59.5831003354255, "EPADERM": 403.043666715322, "FLUTICASONE": 29.93921081434561, "GARDASIL": 1.6232685772812907, "HYDROCORTISONE": 9.034436489467485, "INFANRIX": 28.100623535048165, "JANUMET": 1.7011343259785707, "METHOTREXATE": 3.01407703555923, "MMRVAXPRO": 4.177515936600098, "PROTOPIC": 111.80989377603584, "RINVOQ": 76.47226426717344, "ROTATEQ": 7.809937662654876, "STELARA": 2.10192665890181, "SUBOXONE": 1.3383871511626908, "TREMFYA": 4.441265260678442, "UPADACITINIB": 63.92018175252005, "XOLAIR": 6.10030137690918, "ZOSTAVAX": 2.609811975511752}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/235.json
index 1e01e55772d..ea3dfa5be34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/235.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/235.json
@@ -1 +1 @@
-{"CICLOSPORIN": 12.747335960480354, "DEXAMETHASONE": 21.542497454520117}
\ No newline at end of file
+{"AFINITOR": 0.8340639344756544, "ALIMTA": 2.6168619496727743, "ATOSIBAN": 60.59716447575847, "AVANDAMET": 5.511566529707905, "AVANDIA": 6.5843825648219205, "BRIDION": 18.011893315534063, "BRILIQUE": 3.3674107020081565, "BYETTA": 1.3029233426033289, "CELLCEPT": 2.8219576041971206, "CLOPIDOGREL": 1.877033717064602, "COMBIVIR": 3.1330727746349, "COMIRNATY": 0.2457300474714424, "CYTARABINE": 1.8199840950806636, "DARZALEX": 5.268153293617144, "DEXAMETHASONE": 2.8638010818411157, "ELIQUIS": 0.5215780063264911, "ENTRESTO": 9.137260959862836, "FENTANYL": 5.017621557197493, "FORSTEO": 1.06733659270226, "FYCOMPA": 7.313833577725554, "HUMALOG": 0.7971930241343005, "JAKAVI": 1.5744956846075409, "KYPROLIS": 18.695398726695792, "LANTUS": 1.1673532092833991, "MIDAZOLAM": 7.089552682788282, "MULTAQ": 4.294321954024987, "NEXAVAR": 1.6589551546098509, "OLANZAPINE": 2.4002479727512256, "PEGASYS": 0.550774965668913, "PLAVIX": 1.025458366044308, "PREGABALIN": 2.916422800370386, "PRIVIGEN": 6.181761857393153, "SOLIRIS": 2.364344183645966, "SPIKEVAX": 0.1739906271143375, "SPRYCEL": 4.701705370095726, "SUFENTANIL": 8.897214010958006, "SUTENT": 1.112891988815056, "TRACLEER": 1.905962121605143, "TRACTOCILE": 303.8077193865649, "VAXZEVRIA": 0.0975917152209242, "VYXEOS": 42.04640313285206, "ZYPREXA": 0.6196072965528956, "null": 1.598164825745045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2350.json
index be9562a13e2..ef80608db89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2350.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2350.json
@@ -1 +1 @@
-{"ADENURIC": 6.514832155554581, "AERIUS": 5.271831188305839, "ALIMTA": 3.992593480382662, "BUMETANIDE": 4.744126625006627, "BUSILVEX": 12.529835505686144, "BUSULFAN": 1.3687464410864925, "CAELYX": 6.755571905295695, "COAPROVEL": 3.174139406262642, "EMEND": 21.364570214093018, "ENOXAPARIN": 9.508658938620826, "EUCREAS": 24.383506259140844, "FORXIGA": 1.2421741863903215, "GALVUS": 23.051075740275486, "HYDROCORTISONE": 3.962940278076703, "IBUPROFEN": 1.2306007587417456, "INCIVO": 3.1527492325868445, "JANUVIA": 2.0711471658524383, "KEPPRA": 1.2910947469123657, "KEYTRUDA": 1.9798151958690704, "LEVOFLOXACIN": 1.5429982179730228, "LYRICA": 1.105146465334612, "METFORMIN": 9.986265913816217, "NEXAVAR": 3.4760071191104784, "OLYSIO": 4.730784363599918, "OPDIVO": 1.7352593866114283, "PEGINTERFERON": 1.3670621900937427, "PEMBROLIZUMAB": 3.4839091246619787, "PLAVIX": 1.2497520069623251, "PROTELOS": 7.295777580713275, "RASILEZ": 2.6820779592674424, "SHINGRIX": 1.977395284113873, "SIMPONI": 1.264007823835296, "STIVARGA": 2.726403222348529, "TAMIFLU": 2.2472244374861376, "VFEND": 3.936563750137501, "VORICONAZOLE": 3.087547490244901, "XARELTO": 2.135694196566929, "ZELBORAF": 4.259977937268271, "null": 2.450141480073126}
\ No newline at end of file
+{"METHOTREXATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2351.json
index 60123c17c96..5e61874634f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2351.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2351.json
@@ -1 +1 @@
-{"ABILIFY": 1.102516168992926, "BUDESONIDE": 1.594502593582392, "BUPRENORPHINE": 2.07891284937889, "EVRA": 17.97830950180935, "GARDASIL": 1.4181978016312842, "IBUPROFEN": 1.512867872540325, "MIRVASO": 68.41485373281414, "NOT": 4.870256629086287, "OMALIZUMAB": 12.253354919744678, "OPSUMIT": 5.437985883156154, "RENVELA": 352.636519738192, "REVATIO": 3.349191792504342, "ZOSTAVAX": 7.734630316258774, "null": 3.5607244408422694}
\ No newline at end of file
+{"ATAZANAVIR": 59.08808077936829, "COMIRNATY": 0.3575133052624142, "RITUXIMAB": 26.33279332047389, "null": 0.3225896037994684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2352.json
index 7350c695b86..0db5e3ef797 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2352.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2352.json
@@ -1 +1 @@
-{"ROTATEQ": 51.23444185689549, "SYNAGIS": 38.7021861099303, "null": 2.1444215425600053}
\ No newline at end of file
+{"CICLOSPORIN": 26.347724086867423, "null": 0.4502336298824811}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2353.json
index 822ed2f0777..0c9979c2657 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2353.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2353.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 2.50320878258883, "COSENTYX": 1.4158685969619258, "ERLEADA": 12.692730411205076, "IBUPROFEN": 3.098039465898974, "ICLUSIG": 16.309643829841363, "JANUVIA": 3.1637372916046536, "KEPPRA": 2.302434992972663, "KEYTRUDA": 1.2474826127805974, "LAMIVUDINE": 8.587223678650858, "LEVOFLOXACIN": 2.669590634810534, "NEXAVAR": 3.940516452845788, "PEGASYS": 1.175655308926402, "PLAVIX": 2.6214398934785423, "STELARA": 4.428765566129229, "STIVARGA": 3.8163338805428335, "VFEND": 6.396929270622333, "VORICONAZOLE": 6.540864814234395, "null": 2.731070490524626}
\ No newline at end of file
+{"COMIRNATY": 0.2411594080338703, "GARDASIL": 24.386742688455826, "XYREM": 480.4490485530634, "null": 1.1922998405818055}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2354.json
index f016591bc47..ee9db6c6bef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2354.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2354.json
@@ -1 +1 @@
-{"ADENURIC": 7.674214458958129, "ALIMTA": 2.545215994788846, "AMIKACIN": 5.746425597486221, "APROVEL": 5.291065492717791, "BRILIQUE": 1.5161294042825928, "CAELYX": 2.9702628391934014, "CANCIDAS": 13.350111919498111, "CICLOSPORIN": 3.272540011830775, "CLOPIDOGREL": 1.1235230515017065, "COSENTYX": 4.553229767904019, "CUBICIN": 4.468505202781701, "DESLORATADINE": 7.623199009910531, "DEXAMETHASONE": 1.1510910783755253, "EMEND": 6.2066133312875165, "ERLEADA": 15.82085825707848, "FENTANYL": 1.6124583282210168, "HUMIRA": 2.3024452415661725, "IBUPROFEN": 2.401161443636788, "INCIVO": 5.134749339016444, "ISENTRESS": 3.798553611684029, "LEVEMIR": 1.656338182690474, "LEVETIRACETAM": 1.1519000523927552, "MABTHERA": 5.151369433240756, "METHOTREXATE": 3.624599497675807, "MICARDIS": 2.991691199469896, "NEXAVAR": 1.5808245222932258, "OPDIVO": 1.7057489627634812, "PEGINTRON": 1.671672129202662, "PLAVIX": 3.0306962728208697, "PRIVIGEN": 2.0205750252300785, "RINVOQ": 1.6795201196094551, "SKYRIZI": 7.194891813052414, "STELARA": 4.55929474361749, "STIVARGA": 3.2921134231959983, "TAMIFLU": 1.0977222819307466, "TREMFYA": 2.199418167848877, "VFEND": 5.70596912895872, "ZELBORAF": 9.615550492607357, "null": 2.849320693544969}
\ No newline at end of file
+{"ABACAVIR": 0.1740152595433712, "ABATACEPT": 0.374922965076974, "ACLIDINIUM": 10.95899860812604, "ACTOS": 6.79042574734636, "ACTRAPID": 1.295741133808034, "ADALIMUMAB": 0.1180961502255513, "AFINITOR": 0.6421173754156002, "AIMOVIG": 0.4577541778694556, "ALISKIREN": 21.66201905894724, "ANAKINRA": 2.645297707884326, "ANORO": 1.1243296566390943, "APIDRA": 5.56654018953342, "APREMILAST": 0.8107487983072694, "APROVEL": 1.0655184158282889, "ARAVA": 0.489208749716846, "AUBAGIO": 0.9226931307304798, "AVAMYS": 1.8682457076540324, "AVANDIA": 0.4757437211786067, "AVASTIN": 0.5664390259407708, "AZATHIOPRINE": 1.6026417219568891, "AZOPT": 7.815669624254697, "BENLYSTA": 0.5923999773165274, "BEOVU": 4.149969651199775, "BORTEZOMIB": 1.1201619047889884, "BOSULIF": 0.8153501036939212, "BRAFTOVI": 0.6699606551550418, "BUDESONIDE": 0.3967667744778943, "BYDUREON": 2.6498002734228523, "BYETTA": 3.0331457871395338, "CELLCEPT": 1.689498262077492, "CHAMPIX": 0.1177496429978402, "CIALIS": 1.932506862781869, "CICLOSPORIN": 0.9746009936939588, "CIMZIA": 1.0445261453508186, "CLOPIDOGREL": 0.5737260290235607, "COMIRNATY": 0.0536529229535725, "COSENTYX": 0.6558365652553403, "CYMBALTA": 0.6411074801960239, "DEXAMETHASONE": 1.1908737685502158, "DOCETAXEL": 0.5387566666187281, "DULAGLUTIDE": 2.9450859652712165, "DUPIXENT": 7.502553720239467, "ELIQUIS": 2.5695655034393385, "ENBREL": 1.4961398315983765, "ENTRESTO": 0.4735265891729387, "ENTYVIO": 2.112047014879461, "ENZALUTAMIDE": 1.683594192559538, "ESBRIET": 0.7940295547205883, "ESOMEPRAZOLE": 0.856243792567703, "EVENITY": 1.5320255599812778, "EVISTA": 4.319203853472248, "EXFORGE": 1.4286765015313367, "EXJADE": 1.2862482701579112, "EYLEA": 11.083478599867084, "FASENRA": 0.4855208204140499, "FASLODEX": 1.127403088272247, "FLUTICASONE": 4.090511290356331, "FORSTEO": 2.2514456164716066, "FORXIGA": 0.5174276186679032, "GALVUS": 2.304629544801021, "HALAVEN": 1.012079403042189, "HIZENTRA": 0.6614322829055965, "HUMALOG": 9.839602503008166, "HUMIRA": 2.679841297942496, "HYDROCHLOROTHIAZIDE": 5.047155231959379, "HYDROCORTISONE": 2.132282217373119, "IBRANCE": 3.2745940505915128, "IBUPROFEN": 0.2461553097157992, "INCIVO": 0.3996445896107002, "INCRUSE": 3.797578380517582, "INLYTA": 0.5215087889074819, "INSULIN": 3.933209615028216, "JAKAVI": 0.2680754049811363, "JANUMET": 1.8618709519284455, "JANUVIA": 2.010877773722391, "JARDIANCE": 0.6264285548050961, "KAFTRIO": 2.713229694174179, "KEPPRA": 0.4021274625488517, "KEYTRUDA": 0.40001059543454, "LANTUS": 17.612476272839668, "LEFLUNOMIDE": 0.965557094893009, "LEVEMIR": 7.626624210248692, "LEVOFLOXACIN": 0.2838488570770244, "LIXIANA": 0.6417466908509449, "LONSURF": 0.7395056440625176, "LYRICA": 1.0263303514399251, "MEKINIST": 0.5184021337207008, "MELATONIN": 1.6224901959272016, "MEPOLIZUMAB": 2.1421134509697866, "METHOTREXATE": 1.3518783036600996, "MICARDIS": 0.7901844973927659, "MULTAQ": 0.6455717832203095, "MYCOPHENOLATE": 0.6181189735465451, "NEVANAC": 4.195486144769688, "NINLARO": 3.676902182580594, "NOT": 1.891818522983277, "NOVORAPID": 0.351800364070057, "NUCALA": 1.112308142819728, "OFEV": 0.5247211984852073, "OLANZAPINE": 0.3145710606821376, "OMALIZUMAB": 1.6700491213500634, "OPDIVO": 0.2486083595820557, "OPSUMIT": 0.5152604642782141, "ORKAMBI": 1.7123798053659012, "OXYBUTYNIN": 1.9222771698501149, "PANTOPRAZOLE": 0.6067584329197235, "PEGASYS": 0.5904114466601351, "PEGINTRON": 0.9641358413010336, "PLAVIX": 0.8776911132579936, "PROTOPIC": 13.523531574228867, "RAPAMUNE": 1.7183352357251382, "RASILEZ": 1.2164697476427573, "RELVAR": 1.966759561563418, "REVATIO": 3.0218606753069643, "REVLIMID": 1.9372646146548091, "RINVOQ": 1.0896941702007228, "RITUXIMAB": 0.7276877404576205, "ROACTEMRA": 0.4121137127110099, "RUBRACA": 0.7396520439720649, "RUCONEST": 1.8730686107705257, "SHINGRIX": 0.4214533565492103, "SILDENAFIL": 0.6888305725773523, "SIMPONI": 2.621181411870292, "SOLIRIS": 0.460800569826355, "SPIKEVAX": 0.0396910387498998, "SPRYCEL": 1.1273393585714264, "STELARA": 1.2800906586942278, "SUTENT": 0.5512213915980887, "TAGRISSO": 0.6625250056923586, "TASIGNA": 0.8980008227734453, "TOUJEO": 7.476190820516678, "TOVIAZ": 2.5011124588853395, "TOZINAMERAN": 0.1694449775941914, "TRELEGY": 4.939743372483955, "TREMFYA": 0.8313229138689855, "TRULICITY": 1.766234782287679, "VAXZEVRIA": 0.0287442119439461, "VFEND": 0.4044313834665153, "VIAGRA": 4.892272306849099, "VICTOZA": 3.3926261458996727, "VIMPAT": 0.5832353480018941, "VOTRIENT": 0.5769690075054329, "XELJANZ": 4.189414149426043, "XOLAIR": 0.6907307143980527, "XTANDI": 0.665632133734818, "XYREM": 1.027286681450598, "ZOMETA": 4.2491718357283785, "ZOSTAVAX": 7.04645376340058, "ZYPREXA": 0.744811565115917, "null": 1.411171162876237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2355.json
index 2dbc87372ff..bb1ba656f0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2355.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2355.json
@@ -1 +1 @@
-{"COMIRNATY": 1.028932376961931}
\ No newline at end of file
+{"null": 2.94070486443174}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2356.json
index a610c16e23d..35750b58286 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2356.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2356.json
@@ -1 +1 @@
-{"EMEND": 188.61368844580625, "PEGASYS": 7.027374826211197}
\ No newline at end of file
+{"ZOSTAVAX": 97.67326457986672, "null": 0.4064585265653785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2357.json
index ad1f4645a4e..008a8fa9d8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2357.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2357.json
@@ -1 +1 @@
-{"ARAVA": 3.6592529912643257, "CIMZIA": 5.9649045740410855, "COSENTYX": 10.67243489242479, "KEYTRUDA": 7.074087587074197, "NEXAVAR": 2.076956033137758, "OPDIVO": 6.18950933479755, "PEGASYS": 1.2789885932940588, "SIMPONI": 12.330791412920032, "STELARA": 2.7093565402621667}
\ No newline at end of file
+{"SHINGRIX": 10.832120897159616, "ZOSTAVAX": 182.8623375229244, "null": 0.3647346038617424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2358.json
index 5114634d8c5..0f488d6b19e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2358.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2358.json
@@ -1 +1 @@
-{"ZOSTAVAX": 55.37455434208067}
\ No newline at end of file
+{"ABATACEPT": 1.0397816623283918, "APIDRA": 4.740773584144844, "ARAVA": 0.9497914087152776, "BENLYSTA": 3.2524693257018487, "BYETTA": 13.073975548849733, "CICLOSPORIN": 1.0206100577729604, "CIMZIA": 0.9008698718968408, "ELIQUIS": 1.4696686551284983, "EYLEA": 33.26425676950349, "HUMALOG": 1.5025612539816706, "INCRUSE": 22.82100302744276, "INSULIN": 2.009528693896498, "JANUMET": 11.270532916097508, "JANUVIA": 8.527728452256126, "LANTUS": 29.512634249087387, "LEVEMIR": 11.118244393162406, "MEPOLIZUMAB": 3.756138440232691, "TRELEGY": 6.588579092662127, "VELTASSA": 8.733156986795626, "VICTOZA": 6.768167624028753, "VOTRIENT": 3.102775735170774, "ZOSTAVAX": 7.68300358117285, "null": 1.536469292734847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2359.json
index b971f513a68..f67bb4fccae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2359.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2359.json
@@ -1 +1 @@
-{"CELLCEPT": 3.8825634267607088, "CICLOSPORIN": 3.574179365044152, "CYMBALTA": 2.729272434751405, "FAMPYRA": 8.371358691311203, "GARDASIL": 2.425912937723406, "HUMAN": 10.006971464587856, "KEYTRUDA": 8.577190348460954, "PEGASYS": 1.00006277120715, "TOZINAMERAN": 2.04070475777544, "XELJANZ": 2.6632195864470702}
\ No newline at end of file
+{"null": 1.1042497054935116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/236.json
index c57232a4ba2..10293ceaa02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/236.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/236.json
@@ -1 +1 @@
-{"null": 1.0073536249268118}
\ No newline at end of file
+{"ABILIFY": 0.7202820248540598, "ADVAGRAF": 15.329073606999035, "AFINITOR": 0.6201423544013108, "ALEMTUZUMAB": 3.1329514767719058, "ALIMTA": 1.9784558776545769, "ANORO": 2.085089840636897, "APROVEL": 2.472991548016431, "ARAVA": 0.1912111507955284, "ASPARAGINASE": 2.955839166215123, "ATAZANAVIR": 1.7950597938696418, "AUBAGIO": 0.5113368827179374, "AVASTIN": 1.4716209488483305, "BEVACIZUMAB": 1.0260059600788376, "BORTEZOMIB": 3.196000370771182, "BUPRENORPHINE": 0.8797505332420811, "BUSILVEX": 14.320446438032931, "BUSULFAN": 12.638460184326512, "CANCIDAS": 5.166730857925002, "CARFILZOMIB": 4.094149838556442, "CARMUSTINE": 3.9642173008982144, "CASPOFUNGIN": 8.445803643022145, "CELLCEPT": 5.886055921649863, "CHLORHEXIDINE": 1.3740796884634237, "CICLOSPORIN": 2.625351660784183, "CIMZIA": 0.3179476169747509, "CLOPIDOGREL": 0.2840276301028631, "COMIRNATY": 0.142322779436144, "CUBICIN": 8.728420295067407, "CYTARABINE": 3.0476904407998053, "DEXAMETHASONE": 2.9738023680935077, "DOCETAXEL": 2.415359606715911, "ELIQUIS": 0.4934550408593786, "ENBREL": 1.0335417489373473, "ERBITUX": 5.644861881524675, "EXJADE": 1.1178023550096106, "FENTANYL": 3.381867516793409, "FILGRASTIM": 5.646135107770378, "GANCICLOVIR": 6.5106134136318365, "HUMAN": 2.959360492051966, "HYDROCORTISONE": 1.499417043268566, "IBUPROFEN": 2.382062540116234, "ICLUSIG": 1.957711064729029, "INCIVO": 2.0402518939352268, "IRESSA": 3.937171148402339, "JAKAVI": 2.08540070567166, "JARDIANCE": 0.3469803577923284, "JEVTANA": 2.651218122067656, "KALETRA": 5.862769527333646, "KEPPRA": 0.388370002347227, "KEYTRUDA": 1.9434688523634105, "KYPROLIS": 8.637716010481396, "LEMTRADA": 2.1480643623008238, "LEVOFLOXACIN": 2.114462457888786, "LYRICA": 0.6242237265194884, "MABTHERA": 3.929758691381151, "METHOTREXATE": 2.908037680598957, "MIDAZOLAM": 4.233486961235872, "MYCOPHENOLATE": 2.926447753267604, "NEULASTA": 6.764957474492991, "NEXAVAR": 0.3861432509284274, "NOVOSEVEN": 10.83044446029163, "NPLATE": 2.977634247453474, "OLANZAPINE": 1.453539606176499, "OPDIVO": 0.8178012062551921, "OPSUMIT": 0.9756381679499236, "PEGASYS": 0.8374000574908242, "PEGINTERFERON": 1.3746886126725184, "PEGINTRON": 3.177103189258625, "PLAVIX": 0.3829174870324139, "PRIVIGEN": 1.751130553076276, "REMDESIVIR": 27.487064681601712, "RIBAVIRIN": 1.7367321390226582, "RITUXIMAB": 2.66460338998514, "ROACTEMRA": 1.6672506936708191, "SILDENAFIL": 1.788466661137252, "SIMPONI": 0.4069438849653027, "SOLIRIS": 1.431884568563481, "SPIKEVAX": 0.138515315963919, "STELARA": 0.3239402107442621, "SUBOXONE": 0.4778633975963804, "SUFENTANIL": 4.355654829220852, "SUTENT": 0.1790080502124098, "SYNAGIS": 2.907248433349792, "TAGRISSO": 1.553166663580991, "TAMIFLU": 6.679424789011901, "TASIGNA": 0.6768131650901219, "THIOTEPA": 17.10351741163306, "TIGECYCLINE": 22.522066524966064, "TOZINAMERAN": 0.1510210291834443, "TRACLEER": 2.070060503098204, "VAXZEVRIA": 0.358655860347747, "VEKLURY": 10.85678374776395, "VIAGRA": 0.6248923435769322, "VORICONAZOLE": 3.789822796196181, "XELJANZ": 0.2856575888254787, "XOLAIR": 0.3717308633463678, "ZYPREXA": 0.5385528976174334, "null": 1.5925767453826911}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2360.json
index 50fb8dcf832..b6a8f29d306 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2360.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2360.json
@@ -1 +1 @@
-{"null": 1.1934086214474564}
\ No newline at end of file
+{"APIDRA": 27.85756004649461, "DEXAMETHASONE": 15.34273805360477, "EYLEA": 27.34296608596833, "null": 1.1305869775467334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2361.json
index 5abb250bcb3..ff8670759ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2361.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2361.json
@@ -1 +1 @@
-{"ALIMTA": 41.13463772213367, "ROACTEMRA": 46.81089203782034, "null": 1.2619128787724594}
\ No newline at end of file
+{"ADALIMUMAB": 10.96363861421304, "BENLYSTA": 4.284805757933276, "COMIRNATY": 0.9961401176448946, "MMRVAXPRO": 18.710368379659894, "MODERNA": 2.745513515077157, "RELVAR": 26.412475179229464, "SIMPONI": 3.118958443952325, "SPIKEVAX": 0.4124389662482991, "SUTENT": 1.1273121130388328, "TOZINAMERAN": 0.2982207753467449, "VAXZEVRIA": 0.7379530082542519, "null": 0.7572283587669241}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2362.json
index 1e70824cdf6..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2362.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2362.json
@@ -1 +1 @@
-{"CELLCEPT": 28.709174584390997, "OMALIZUMAB": 42.588776709148654}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2363.json
index e6d452bbe60..7625a5de38f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2363.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2363.json
@@ -1 +1 @@
-{"NEXAVAR": 31.28700167329784, "null": 1.121658237717915}
\ No newline at end of file
+{"ABILIFY": 3.993527230526319, "ARIPIPRAZOLE": 28.403281983465774, "CHAMPIX": 1.4837549650653783, "COMIRNATY": 0.0277332908918609, "CYMBALTA": 0.9221792470356316, "DEXMEDETOMIDINE": 50.98857888655453, "GARDASIL": 0.867061793101578, "KEPPRA": 4.751063121539212, "LATUDA": 13.731708102417722, "OLANZAPINE": 47.712803230972, "RISPERIDONE": 22.139566954908773, "TOZINAMERAN": 0.2057691741714406, "ZYPREXA": 14.01385406055225, "null": 1.880586283420134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2364.json
index 8710c7865a4..696224926ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2364.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2364.json
@@ -1 +1 @@
-{"CAELYX": 354.2972950340737}
\ No newline at end of file
+{"FENTANYL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2365.json
index aa0be3904e0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2365.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2365.json
@@ -1 +1 @@
-{"AVASTIN": 18.024381748471328, "BEOVU": 410.9126513395976, "BRAFTOVI": 80.95807066782193, "BROLUCIZUMAB": 498.59283968601534, "EYLEA": 372.9459482733552}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2366.json
index af7da3a90e2..803f5c1c018 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2366.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2366.json
@@ -1 +1 @@
-{"SUBOXONE": 86.21226043552073, "null": 1.423257841715107}
\ No newline at end of file
+{"null": 2.691503249986645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2367.json
index 0afc1b26cac..5c645544538 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2367.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2367.json
@@ -1 +1 @@
-{"null": 12.617776279756622}
\ No newline at end of file
+{"OPSUMIT": 215.5749899042078, "TRACLEER": 79.899170970412, "null": 1.238367032018295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2368.json
index d6477e98a31..160f36fb703 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2368.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2368.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 14.514236001682152, "COMBIVIR": 3.5691232798661567, "EMTRICITABINE": 6.821779447928377, "EPIVIR": 8.52934270670302, "FENTANYL": 2.872340659376473, "IBUPROFEN": 1.3039818483237426, "INFANRIX": 31.43178285960059, "KALETRA": 4.219132989062504, "KEPPRA": 5.960445685552384, "LACOSAMIDE": 4.735219401114477, "LAMIVUDINE": 10.001351611838178, "LEVETIRACETAM": 5.288146215482204, "MMRVAXPRO": 1.6701950690424228, "NEVIRAPINE": 17.136368666454633, "PREVENAR": 8.455937997491173, "ROTATEQ": 2.680326354591637, "SUBOXONE": 7.5887846433116035, "SYNAGIS": 3.5928155540650537, "VIMPAT": 4.752384742999301, "null": 6.400478729412912}
\ No newline at end of file
+{"ELIQUIS": 3.176220781095181, "JANUMET": 6.176997139851176, "JANUVIA": 8.292377821636826, "LANTUS": 2.012724051467617, "OPSUMIT": 51.98702951620403, "TRACLEER": 28.57035584100068, "null": 1.2846829042978385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2369.json
index b2e7b6bb632..e183c09b050 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2369.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2369.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"OPSUMIT": 45.29965394003322, "null": 1.9308669274594548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/237.json
index 7d9055a684c..c351436ed96 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/237.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/237.json
@@ -1 +1 @@
-{"null": 2.0638454372262287}
\ No newline at end of file
+{"ABILIFY": 0.6090704361344317, "ADEMPAS": 3.2624012654356576, "AFINITOR": 0.8007546245176397, "ALEMTUZUMAB": 1.6777698878233729, "ALIMTA": 2.7962291805598927, "AMINOSALICYLIC": 1.1049593124491337, "ARAVA": 0.1538381996922381, "AVANDIA": 2.3903323532447263, "AZACITIDINE": 3.998907967458603, "BEDAQUILINE": 7.586738868796107, "BENLYSTA": 0.7953318600495364, "BRIDION": 3.050363444622387, "BUSULFAN": 1.6999219650288666, "BYETTA": 1.3369766805818617, "CABOMETYX": 1.5469166096819642, "CANCIDAS": 4.904692316666604, "CASPOFUNGIN": 3.2844794747513832, "CELLCEPT": 1.1406592307359786, "CICLOSPORIN": 1.2221286004133949, "CLOPIDOGREL": 1.1295959922718115, "COMIRNATY": 0.2529220587588099, "CUBICIN": 2.9269676779482365, "CYMBALTA": 0.4668725592371991, "CYTARABINE": 2.396873713587975, "DEXAMETHASONE": 3.331387310564768, "DOCETAXEL": 0.7899030987921906, "ELIQUIS": 2.087937057208325, "ESBRIET": 4.169142276140492, "EXJADE": 1.0028559099930665, "FASENRA": 3.2230208271739693, "FASLODEX": 0.7292390859496812, "FENTANYL": 2.5672483009048106, "FILGRASTIM": 4.631085458461365, "FIRDAPSE": 5.756416375761702, "FORSTEO": 0.3831161565648438, "HUMALOG": 0.4859079482420366, "HYDROCORTISONE": 1.7094727606138618, "IBRANCE": 0.3792753868996046, "INSULIN": 0.6904185801778971, "INVOKANA": 16.90788920558382, "IRESSA": 6.8508167402690034, "IRINOTECAN": 1.752084606958747, "JAKAVI": 0.9075247834382648, "JANUMET": 1.820662243156882, "JANUVIA": 1.864076750607004, "JARDIANCE": 0.8022260779453766, "KALETRA": 1.010194439995554, "KEYTRUDA": 1.6430540677934646, "KYMRIAH": 1.6698980274242183, "KYPROLIS": 3.782422941823484, "LAMIVUDINE": 3.186311737475385, "LANTUS": 0.7527348421152087, "LEVOFLOXACIN": 0.7038146079450651, "MEPOLIZUMAB": 1.589888890805026, "MIDAZOLAM": 2.123807371826694, "MYCOPHENOLATE": 1.870227713268693, "NAGLAZYME": 5.054972475146406, "NEULASTA": 1.1378809326634478, "NEXAVAR": 0.8927730857355313, "NOXAFIL": 4.208014704671731, "NPLATE": 3.064471804300969, "NUCALA": 1.9068893576489088, "OFEV": 2.695192903565324, "OLANZAPINE": 1.3930817289150033, "ONGLYZA": 7.949871630144918, "OPDIVO": 1.2112850583065895, "OPSUMIT": 6.6264703053417975, "PEGASYS": 0.5367901031770904, "PEGINTRON": 0.7852964219968813, "PLAVIX": 1.0389358510703357, "PRIVIGEN": 1.1687190738124058, "REMDESIVIR": 26.21272516017258, "REVATIO": 2.910069441583389, "RITUXIMAB": 1.560705104387211, "ROACTEMRA": 2.1405611589376923, "SILDENAFIL": 2.084180572034294, "SOLIRIS": 1.3122239709751171, "SPIKEVAX": 0.8999746970181645, "SPINRAZA": 16.77516946998773, "SPRYCEL": 1.1753617420447184, "STELARA": 0.5173799918023798, "STIVARGA": 0.8275589430681973, "SUTENT": 0.4304852157182662, "SYNAGIS": 6.42624382479321, "TAGRISSO": 1.5984066759605466, "TAMIFLU": 1.5180179236661702, "TORISEL": 3.3555354295531385, "TOZINAMERAN": 0.1820521180617256, "TRACLEER": 6.624762921550798, "TRELEGY": 1.6485800466503575, "VAXZEVRIA": 0.1369405875119572, "VEKLURY": 6.433474588328673, "XARELTO": 3.711039483353092, "XELJANZ": 0.4118355021292758, "XOLAIR": 1.0122551537329263, "YESCARTA": 1.892349863683479, "ZOSTAVAX": 2.0040366882893186, "ZYPREXA": 0.760310583068675, "null": 1.075655902217903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2370.json
index 453a7241a25..f714e6eb69c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2370.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2370.json
@@ -1 +1 @@
-{"ASPARAGINASE": 49.03196797447769, "LEVETIRACETAM": 17.14280969596731, "SUBOXONE": 7.320469795924347, "null": 2.425933965096201}
\ No newline at end of file
+{"NAGLAZYME": 596.0261588194577, "null": 0.6588557304492099}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2371.json
index ccec74fbe3e..66cee01b52b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2371.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2371.json
@@ -1 +1 @@
-{"null": 2.468797304151005}
\ No newline at end of file
+{"null": 1.2409658366524328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2372.json
index b7bb6a90601..0f20649561a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2372.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2372.json
@@ -1 +1 @@
-{"IBUPROFEN": 29.044063949630686, "NEULASTA": 587.2190421473565, "null": 1.2290259757396174}
\ No newline at end of file
+{"PACLITAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2373.json
index b27e594ae61..8409abf0d5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2373.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2373.json
@@ -1 +1 @@
-{"OPSUMIT": 92.04116868389067, "TRACLEER": 36.71919103493391, "null": 2.637673923603099}
\ No newline at end of file
+{"AMBRISENTAN": 103.27590703428268, "OPSUMIT": 87.14104146174087, "TRACLEER": 45.369781943060254, "null": 2.024602822496236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2374.json
index 153e1504fdd..7d8d28387a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2374.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2374.json
@@ -1 +1 @@
-{"null": 2.3778832419943305}
\ No newline at end of file
+{"OPSUMIT": 158.10465886858586, "null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2375.json
index 852e58a1267..02be3f518d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2375.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2375.json
@@ -1 +1 @@
-{"ADEMPAS": 16.9709243175089, "APIDRA": 10.872104828391423, "FIASP": 56.77109366926445, "INSULIN": 3.172652224313855, "LANTUS": 8.740144279447813, "LEVEMIR": 38.12530261797387, "NOVORAPID": 81.84880374389091, "OMNITROPE": 96.78804880737115, "OPSUMIT": 13.271947843482458, "TRACLEER": 8.127515255569795, "TRESIBA": 19.875154519408607, "null": 2.039619468907754}
\ No newline at end of file
+{"ADCIRCA": 31.09215039085773, "ADEMPAS": 58.58749674255598, "CYTARABINE": 6.249086575690802, "NAGLAZYME": 32.256401947237606, "OPSUMIT": 88.62557391079936, "REVATIO": 13.674166652125068, "TRACLEER": 45.78843151475421, "YONDELIS": 82.19907633765617, "null": 2.091934374152435}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2376.json
index 5216b0043e1..39ccd412ae1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2376.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2376.json
@@ -1 +1 @@
-{"null": 3.787364818909382}
\ No newline at end of file
+{"REVLIMID": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2377.json
index c1cdb4814e8..5d9aacf47c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2377.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2377.json
@@ -1 +1 @@
-{"null": 3.99137987232265}
\ No newline at end of file
+{"null": 3.523673233771536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2378.json
index fec6e689781..26cee55c957 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2378.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2378.json
@@ -1 +1 @@
-{"null": 2.8178149482102506}
\ No newline at end of file
+{"CLOPIDOGREL": 27.185684016112884, "PLAVIX": 79.01161272442363, "null": 0.3017355639313818}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2379.json
index 9b59161fc6d..a1f5a4e85a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2379.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2379.json
@@ -1 +1 @@
-{"AIMOVIG": 8.770505469473079, "APIDRA": 10.500894062131238, "BYDUREON": 27.50218025760453, "COSENTYX": 15.197844020900003, "FASENRA": 18.528252573360245, "FIASP": 27.124172231285534, "INSULIN": 5.845063826092957, "LANTUS": 9.42054227077613, "LEVEMIR": 8.905525675249285, "NOVORAPID": 34.47464415034286, "SAXENDA": 9.49710710207634, "SEMGLEE": 367.6225842969492, "SIMPONI": 15.696902678609572, "STELARA": 5.540496540404582, "TOUJEO": 35.492507007626386, "TREMFYA": 14.985216532288833, "null": 1.4900677065117856}
\ No newline at end of file
+{"CLOPIDOGREL": 6.985577158159716, "ELIQUIS": 7.471960794372554, "OPSUMIT": 34.062850745114886, "PLAVIX": 7.308773189681605, "TRACLEER": 14.83711954210299, "null": 1.848730382660074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/238.json
index 4bcb5a45241..1e02e623a53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/238.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/238.json
@@ -1 +1 @@
-{"ABATACEPT": 2.3489341104905144, "ABILIFY": 3.5350140969338937, "ADALIMUMAB": 7.10706464012192, "AMIKACIN": 1.6640227999602248, "AMINOSALICYLIC": 6.645147571515391, "ANAKINRA": 1.0792737136492534, "ANORO": 1.5924740818813758, "APIXABAN": 4.124214503198084, "APREMILAST": 21.84387452660102, "ARAVA": 4.650861613686885, "ARIPIPRAZOLE": 2.173322791081207, "AUBAGIO": 1.0005130922561225, "AVONEX": 5.846551572097564, "BENLYSTA": 3.0537326151522164, "BRINTELLIX": 1.7791074387529875, "BRIVARACETAM": 7.406526535955066, "BRIVIACT": 7.657926244819743, "BUDESONIDE": 4.845263320068497, "BUPIVACAINE": 3.165648983819231, "BYETTA": 1.1302929148870713, "CABOMETYX": 1.2760736404289323, "CARDIAC": 158.68681068071453, "CELECOXIB": 1.5799550389821329, "CIMZIA": 3.356006351569542, "COSENTYX": 1.566374800819251, "DARUNAVIR": 2.4703017974985664, "DARZALEX": 1.8106291644460832, "DULOXETINE": 1.3283248018254483, "ENBREL": 5.681285175493105, "ENTYVIO": 2.8201032404689097, "FASENRA": 1.225192334665998, "FASLODEX": 1.3854469677354493, "FENTANYL": 1.8055533239148889, "GARDASIL": 1.3476760028402963, "HIZENTRA": 1.1760528534222714, "HUMIRA": 5.371628118115433, "HYDROCORTISONE": 2.2134298841100817, "INCRUSE": 3.8641377412606337, "INTUNIV": 46.95851037294072, "INVEGA": 4.44714800354435, "ISENTRESS": 1.7954813269441297, "JANUMET": 1.0526596062486144, "KEPPRA": 4.460738890619583, "KEYTRUDA": 1.1070914725213272, "KIOVIG": 1.7506174176660985, "LACOSAMIDE": 1.6648235477501816, "LEFLUNOMIDE": 2.203797540593831, "LEVETIRACETAM": 2.524222450790091, "LUMYKRAS": 15.624488438250165, "LYNPARZA": 2.217153309336953, "LYRICA": 1.2668872411824468, "MEKINIST": 1.0263247768181116, "MEPOLIZUMAB": 6.003095183699547, "NEULASTA": 3.011316265978972, "NEXAVAR": 1.3907776157671197, "NINLARO": 3.734081652832816, "NOT": 1.2593476221542006, "NPLATE": 1.7220628652619168, "NUCALA": 3.607589687386088, "OLANZAPINE": 1.4351610735408342, "OXYBUTYNIN": 2.7218198777741502, "PIRFENIDONE": 21.581837887027127, "PREGABALIN": 1.3842365214376875, "REMICADE": 2.427842356575271, "REVLIMID": 2.113249041243876, "RINVOQ": 4.229208421116481, "RISPERIDONE": 3.012132011989039, "RUBRACA": 2.6676802329273364, "SIMPONI": 2.106367527193627, "STELARA": 1.3181130796391936, "STIVARGA": 1.458441100661591, "TRELEGY": 1.553307182418176, "VIMPAT": 1.9656226595034405, "VOTRIENT": 4.670840317891651, "XARELTO": 1.1891445305112274, "XTANDI": 1.2056413524641063, "XYREM": 2.341548170670347, "ZEJULA": 9.046900481954678, "ZOSTAVAX": 1.3395564033410616, "null": 1.1142983025095163}
\ No newline at end of file
+{"null": 0.6378939197264512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2380.json
index 6e80d019036..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2380.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2380.json
@@ -1 +1 @@
-{"AIMOVIG": 4.530822690466712, "APIDRA": 10.14842775513015, "BYDUREON": 34.04987237920876, "BYETTA": 4.649818286858428, "COSENTYX": 2.1347816771147965, "FASENRA": 21.61153615012997, "FIASP": 28.747244215367296, "LANTUS": 7.268598659301825, "LEVEMIR": 11.086550692073589, "NOVORAPID": 42.2995124722648, "OPSUMIT": 4.329066948947553, "SAXENDA": 10.632177693672356, "SIMPONI": 2.192446137846548, "TOUJEO": 18.7685460851876, "TRESIBA": 33.96164898780047, "null": 3.2405284963705507}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2381.json
index b0c66916128..f40fe4b3d63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2381.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2381.json
@@ -1 +1 @@
-{"SIMPONI": 225.2386166312527, "STELARA": 40.498033954947694, "TREMFYA": 86.11089488814868}
\ No newline at end of file
+{"ADCIRCA": 23.725707624537367, "ADEMPAS": 37.15445880914137, "FILGRASTIM": 25.24170152175138, "OPSUMIT": 66.02385597740883, "REVATIO": 13.248195541234816, "SOLIRIS": 9.406026243120222, "TRACLEER": 38.86993871788317, "null": 1.4599316332175687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2382.json
index b2e7b6bb632..8e5309259bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2382.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2382.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"null": 1.02079846655359}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2383.json
index acc6b27d0dd..7031434742f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2383.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2383.json
@@ -1 +1 @@
-{"AIMOVIG": 207.13185037430225, "ARANESP": 32.496851461792616, "BYDUREON": 9.675071457351104, "COSENTYX": 4.434522644785563, "EYLEA": 6.087893877864897, "LANTUS": 1.190718971996239, "ROACTEMRA": 4.176812386467438, "null": 1.184095620017452}
\ No newline at end of file
+{"OPSUMIT": 136.49071520517364, "null": 1.859973445030348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2384.json
index 62faa25e785..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2384.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2384.json
@@ -1 +1 @@
-{"ADCIRCA": 23.1153981589487, "BUPIVACAINE": 14.97315013106873, "ELIQUIS": 1.1110758675846235, "FENTANYL": 1.890257528773822, "FORSTEO": 12.878530470532452, "HYDROCORTISONE": 52.529716803804256, "IBUPROFEN": 14.15615731070101, "ILARIS": 365.3609996775903, "NEULASTA": 145.9650241685922, "OPSUMIT": 38.55384531699643, "RITUXIMAB": 3.755954533019195, "SPINRAZA": 22.001517168446597, "TESTOSTERONE": 34.210530559679896, "TRACLEER": 7.139094717105061, "null": 1.2768179875535486}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2385.json
index 11d76ffd972..adea616a844 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2385.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2385.json
@@ -1 +1 @@
-{"null": 2.415129997857277}
\ No newline at end of file
+{"null": 1.6086976435080844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2386.json
index 6da6e667bec..b54ee240186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2386.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2386.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"ADCIRCA": 58.61882840648245, "ARAVA": 0.619405926452497, "CYTARABINE": 7.261041774239043, "METHOTREXATE": 13.627545382456027, "NAGLAZYME": 63.43451235684668, "OPSUMIT": 66.76169163414067, "SOLIRIS": 5.933264638663731, "TRACLEER": 28.16796955420939, "null": 1.496610106122593}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2387.json
index 2ca8237c58b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2387.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2387.json
@@ -1 +1 @@
-{"null": 2.156916737865857}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2388.json
index c60decc8107..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2388.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2388.json
@@ -1 +1 @@
-{"ACTRAPID": 44.81649003706615, "APIDRA": 2.672783589001094, "BUPIVACAINE": 9.6928166061272, "BYDUREON": 3.854957170903627, "FENTANYL": 2.0016407519603767, "FIASP": 51.78681692416048, "FORSTEO": 2.7651860017942638, "LEVEMIR": 57.062834096024055, "MIXTARD": 29.74375471385549, "NEULASTA": 10.341102686313691, "NOVORAPID": 82.04485592353478, "OPSUMIT": 1.172774893849222, "SAXENDA": 4.389112637582569, "SIMPONI": 4.065330366951514, "TRESIBA": 20.80422867717287, "VICTOZA": 4.662898401022784, "null": 3.9669781721215625}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2389.json
index faeb6d68c4e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2389.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2389.json
@@ -1 +1 @@
-{"LEFLUNOMIDE": 1472.9822109090417}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/239.json
index d07c6d71734..2e444f90a22 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/239.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/239.json
@@ -1 +1 @@
-{"ABATACEPT": 1.6233827427775214, "ABILIFY": 1.90555141195986, "ADALIMUMAB": 4.230755138928314, "AERIUS": 1.4755025346028827, "ALIMTA": 1.930655371851533, "AMINOSALICYLIC": 4.685938319955347, "APIDRA": 1.4240586379876683, "APIXABAN": 8.715683942305368, "APREMILAST": 1.4205358182856826, "APROVEL": 1.0917692269771957, "ARAVA": 3.3333180071501625, "AVANDAMET": 1.709655002220209, "AVANDIA": 1.4899238536260992, "AXITINIB": 2.3414006515089265, "BARACLUDE": 3.444889351983542, "BEDAQUILINE": 1.976851720198953, "BELANTAMAB": 29.4899366289344, "BENLYSTA": 1.8149227133660188, "BETAFERON": 2.0845571676533283, "BIKTARVY": 2.7364351129835174, "BOCEPREVIR": 3.8930880723798102, "BRAFTOVI": 1.1427009227527432, "BRIDION": 4.02970426153338, "BRINTELLIX": 1.1106379392377763, "BRIVIACT": 4.620994882885323, "BYDUREON": 1.8173767229052784, "BYETTA": 1.24172857177812, "CANCIDAS": 2.683168765401404, "CERTOLIZUMAB": 9.47630056657221, "CERVARIX": 7.263108871264496, "CHLORHEXIDINE": 1.7040257226565472, "CIMZIA": 2.404089659482425, "CUBICIN": 1.6011848040725567, "DARZALEX": 2.896361976859951, "DESCOVY": 2.226888134868513, "ELIQUIS": 5.68256774900491, "ELLAONE": 1.3060152131966478, "EMEND": 6.811978961626962, "EMTRICITABINE": 3.150107791354043, "ENALAPRIL": 8.35749858790516, "ENBREL": 1.2771714653724575, "ENTYVIO": 1.6623842576037249, "ERLEADA": 1.5639902942535682, "EVENITY": 1.569634080469532, "FLORAJEN": 164.5255632399122, "GALAFOLD": 4.02219839339429, "GARDASIL": 3.220604709138017, "I": 96.01779975622595, "INFLIXIMAB": 2.9043522442495178, "IPILIMUMAB": 1.031648108267743, "IRON": 5.139577155599635, "ISENTRESS": 13.672767539142034, "JANUMET": 7.3105707338232895, "JANUVIA": 9.481294967558572, "KEPPRA": 1.154095412122792, "KEYTRUDA": 12.327030749376284, "KYPROLIS": 1.0332639563466737, "LACOSAMIDE": 1.2045497467950013, "LANTUS": 1.72302453938913, "LOPINAVIR": 2.019915985538593, "MULTAQ": 1.0195273672642315, "NEULASTA": 2.3149816439248965, "NINLARO": 3.0525515701274557, "NORVIR": 2.237508494936895, "NOT": 3.590686376299836, "NOXAFIL": 22.59553898658379, "ONGLYZA": 1.812096015974948, "OPSUMIT": 2.327514727965767, "PEGINTERFERON": 2.486045021160743, "PEGINTRON": 2.0007126100283528, "PEMBROLIZUMAB": 3.387185153110514, "QUTENZA": 2.314865840083234, "REBETOL": 2.837206819599785, "REMICADE": 2.8093108397832336, "REYATAZ": 4.36861513039756, "ROTATEQ": 1.7929161598790275, "RUBRACA": 27.40599369339656, "SIMPONI": 2.8201674592908885, "SPRYCEL": 11.495086735934722, "STELARA": 1.8784200606075727, "SUBOXONE": 3.9337967290276574, "SYCREST": 6.207632202515212, "SYNAGIS": 1.225159937997084, "TEMODAL": 5.161614581684264, "TEMOZOLOMIDE": 1.802894331091012, "VELTASSA": 2.1524767072561164, "VENETOCLAX": 1.8057164838635764, "VIMPAT": 1.1894066398089929, "VOTRIENT": 2.106565205965936, "XARELTO": 1.8384486500674229, "XOFIGO": 1.4291538494146168, "XTANDI": 1.9861329570102608, "YERVOY": 5.021723104558758, "ZEPATIER": 21.46923532415132, "ZOSTAVAX": 2.3096075238192366, "null": 1.1852338736119017}
\ No newline at end of file
+{"COMIRNATY": 0.3263804688633139, "GARDASIL": 5.391267294317867, "SPIKEVAX": 0.246791791956231, "VAXZEVRIA": 0.1550543818053958, "ZOSTAVAX": 38.49046683928115, "null": 0.8054938905763237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2390.json
index aae86cc663f..425edd19760 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2390.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2390.json
@@ -1 +1 @@
-{"ENTRESTO": 245.0806903727404}
\ No newline at end of file
+{"null": 0.9518920967503458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2391.json
index ad080656234..c1bf35299c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2391.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2391.json
@@ -1 +1 @@
-{"LANTUS": 4.120087918166374, "null": 8.10471951408704}
\ No newline at end of file
+{"OPSUMIT": 152.26504081630353, "TRACLEER": 18.204207325980374, "null": 1.924027141425955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2392.json
index 6cc38189220..4d38472217f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2392.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2392.json
@@ -1 +1 @@
-{"FIASP": 327.0282534630534, "LEVEMIR": 61.78094890984487, "NOVORAPID": 239.37985664292012, "TRESIBA": 99.2683663129178, "null": 1.423528289014974}
\ No newline at end of file
+{"OPSUMIT": 94.48444746023128, "null": 1.8107377330359429}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2393.json
index fafd7dea132..147f4a2952c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2393.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2393.json
@@ -1 +1 @@
-{"BUPIVACAINE": 34.58683265480888, "HYQVIA": 134.81785238934387, "OPSUMIT": 18.77176855363161, "SIMPONI": 6.021818327273017, "TRACLEER": 14.312000949565482, "null": 3.057660323197817}
\ No newline at end of file
+{"OPSUMIT": 29.90541253099607, "null": 1.147797449774532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2394.json
index 234e36bd796..510de11f149 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2394.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2394.json
@@ -1 +1 @@
-{"EPOETIN": 9632.533523763224}
\ No newline at end of file
+{"ADCIRCA": 105.13386574166655, "NAGLAZYME": 60.489012398999606, "OPSUMIT": 61.04058956948392, "TRACLEER": 54.724099387738335, "null": 1.4326054592846933}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2395.json
index 49497a2bc16..4db21d0f0df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2395.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2395.json
@@ -1 +1 @@
-{"null": 1.906036144418784}
\ No newline at end of file
+{"null": 0.9598390768183224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2396.json
index 9def0957854..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2396.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2396.json
@@ -1 +1 @@
-{"ACTRAPID": 9.381893517130438, "AIMOVIG": 15.21966480342774, "APIDRA": 25.297186875418888, "ARANESP": 1.9844426964410653, "BYDUREON": 33.62678827150396, "BYETTA": 3.7718318427895663, "CIMZIA": 6.348631306612947, "COSENTYX": 9.570934941244367, "ENTYVIO": 1.8301746401854528, "EVENITY": 2.773834576914907, "FASENRA": 4.170066217293395, "FIASP": 27.18678435800706, "HUMIRA": 1.3302318994728344, "INBRIJA": 63.90759022640978, "INHIXA": 27.629176552394394, "INSULATARD": 13.539088830764417, "INSULIN": 6.8122418767389314, "LANTUS": 22.43846052702027, "LEVEMIR": 17.539454442666727, "NEULASTA": 19.71660762164136, "NOVORAPID": 30.279035304452343, "OMNITROPE": 94.3523044656571, "OPSUMIT": 3.191988160904049, "ROACTEMRA": 1.93593070262572, "SAXENDA": 3.0876532440296365, "SEMGLEE": 208.83513639037133, "SIMPONI": 17.471085411079095, "SKYRIZI": 13.560675352538166, "STELARA": 4.895360930119673, "TOUJEO": 29.77402528459545, "TRACLEER": 1.7754994212511832, "TREMFYA": 55.77075548891202, "TRESIBA": 16.856776104887295, "VICTOZA": 3.4452949900252854, "null": 1.157702329071428}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2397.json
index b4b9d8b33c6..4aab17dd23b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2397.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2397.json
@@ -1 +1 @@
-{"AIMOVIG": 5.256466733102113, "APIDRA": 6.973198821459808, "BYDUREON": 115.81649423853864, "BYETTA": 6.8978785488455605, "COSENTYX": 5.112306632269688, "ENTYVIO": 3.0842280594774034, "FASENRA": 45.11851250063003, "FIASP": 14.11204681725067, "LANTUS": 3.887095327567366, "LEVEMIR": 9.967770233278, "NEULASTA": 12.716821159065075, "NOVORAPID": 26.34448268205088, "OPSUMIT": 21.341079510863743, "SIMPONI": 17.067892173026088, "STELARA": 3.751758283657114, "TOUJEO": 6.918160748120319, "TRACLEER": 12.499527746502226, "TREMFYA": 45.16790059742297, "VICTOZA": 3.250891963986737, "null": 1.341171790965596}
\ No newline at end of file
+{"null": 2.1571591563082437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2398.json
index bb27086a011..09ac4a41088 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2398.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2398.json
@@ -1 +1 @@
-{"FORSTEO": 44.55729213838868}
\ No newline at end of file
+{"null": 1.4941723624369108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2399.json
index 7b283ba41fd..0ebea32b12d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2399.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2399.json
@@ -1 +1 @@
-{"IBUPROFEN": 745.8541047103722}
\ No newline at end of file
+{"null": 2.842174893117785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/24.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/24.json
index 4525c4041f7..c3333eec060 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/24.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/24.json
@@ -1 +1 @@
-{"ASPARAGINASE": 5.133888882265375, "BYETTA": 2.6399743846188577, "CICLOSPORIN": 3.1960376968007145, "CLOPIDOGREL": 5.140017334644753, "CYTARABINE": 3.6750197177021184, "ENOXAPARIN": 13.611243752053204, "ENTYVIO": 1.866241488392646, "EXJADE": 4.693681446594666, "GARDASIL": 1.5097614394861818, "HUMIRA": 1.3631217361169554, "IBUPROFEN": 3.421873907536314, "JANUVIA": 1.6999797630505706, "KALETRA": 2.4648132091433794, "LEVOFLOXACIN": 1.0665752442057796, "METHOTREXATE": 1.1946488658843717, "OLANZAPINE": 1.4702420314845062, "PEGINTERFERON": 2.05175768503502, "ROTATEQ": 8.782813809642887, "STIVARGA": 1.5933160748579882, "TASIGNA": 2.386699136694868, "ZOSTAVAX": 1.8469182205837025, "null": 2.0651347866368277}
\ No newline at end of file
+{"CYTARABINE": 15.57604961825209, "null": 1.5649847880421213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/240.json
index 6c6963429a3..3575317fc9b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/240.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/240.json
@@ -1 +1 @@
-{"COMIRNATY": 1.639722318911992, "COVID19": 6.096755654613295, "GARDASIL": 25.915461537995174, "SPIKEVAX": 1.632204604201518, "VAXZEVRIA": 1.5670346272536164}
\ No newline at end of file
+{"COMIRNATY": 3.8511348502502742, "EFAVIRENZ": 49.32426849592806, "PEGASYS": 2.969714753494276, "null": 0.382588998441843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2400.json
index 19f926a8177..977cb73ddb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2400.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2400.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.7363928615479134, "ACTRAPID": 13.21741262764763, "AIMOVIG": 4.727205347343143, "APIDRA": 5.668482407997738, "BUMETANIDE": 11.105642019747, "BYDUREON": 33.639293559072655, "BYETTA": 3.97291368325473, "COSENTYX": 3.266931655760719, "DUORESP": 29.951979733903997, "ENTRESTO": 1.3778597719338712, "ERENUMAB": 7.634974583620242, "FASENRA": 4.349305004311753, "FIASP": 16.34425790201519, "HYDROCORTISONE": 9.124717752478968, "IBUPROFEN": 2.5537336263098043, "INSULATARD": 11.843774814367356, "LANTUS": 31.86453614509075, "LEVEMIR": 30.10624552781451, "NEULASTA": 7.125461174583649, "NOVORAPID": 24.469430004656537, "OMNITROPE": 17.31809282196066, "OPSUMIT": 2.925824197975192, "PLEGRIDY": 3.2279968254669265, "SAXENDA": 5.053351282439603, "SIMPONI": 11.015274183869888, "STELARA": 1.4127497919283014, "TERROSA": 17.42239485942071, "TESTOSTERONE": 6.05952459091586, "TRACLEER": 2.356471818319452, "TREMFYA": 24.72326713500384, "TRESIBA": 15.91965837454006, "VICTOZA": 4.114687301311931, "null": 2.2658046580962816}
\ No newline at end of file
+{"AVANDAMET": 21.67903078095096, "AVANDIA": 27.96274938235936, "BYETTA": 5.082865079975116, "COMIRNATY": 0.0590384471163626, "ELIQUIS": 2.245339067504558, "HIZENTRA": 5.830117459159651, "JANUMET": 3.061302273370511, "JARDIANCE": 4.015145346142033, "LANTUS": 2.1533329146416773, "OPSUMIT": 28.22278835191216, "SPIKEVAX": 0.2507319666266312, "SYNAGIS": 7.862698151945158, "TRACLEER": 19.746812608045573, "TRELEGY": 6.093320552163183, "ZOSTAVAX": 3.487004768121261, "null": 1.5800712202255731}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2401.json
index 246b25d2e0b..58882cb97f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2401.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2401.json
@@ -1 +1 @@
-{"null": 2.05052867485809}
\ No newline at end of file
+{"OPSUMIT": 32.372858965998226, "SPIKEVAX": 1.5805551199488757, "null": 1.456545919486572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2402.json
index 9953d6d611d..5fddf609954 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2402.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2402.json
@@ -1 +1 @@
-{"LANTUS": 10.136790950380176, "LEVEMIR": 19.43946140360441, "NOVORAPID": 53.05827220231231, "SAXENDA": 31.536713402270976, "SEMGLEE": 3579.844043190258, "null": 1.6821998284515491}
\ No newline at end of file
+{"BUPIVACAINE": 182.06240414838769, "COMIRNATY": 0.1512856646925819, "null": 2.450823072393927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2403.json
index 5a17d162bba..d188876c98f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2403.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2403.json
@@ -1 +1 @@
-{"AMBRISENTAN": 17.347753591515986, "ANGIOX": 152.72878465706273, "BRILIQUE": 11.192878599238936, "BUMETANIDE": 41.90979623314222, "BYDUREON": 7.533384969517858, "CLOPIDOGREL": 6.1674818016265816, "COSENTYX": 1.6887648310849712, "EFIENT": 21.232012085761024, "FIASP": 26.09973944828613, "JANUMET": 3.158311766301718, "JANUVIA": 3.321174009284645, "LANTUS": 1.5589703965403188, "LEVEMIR": 7.443442486982543, "NEULASTA": 8.743292289169052, "NOVORAPID": 11.124646932472244, "OMNITROPE": 52.455892848644005, "OPSUMIT": 9.98034018169426, "PLAVIX": 12.190020800317544, "SIMPONI": 4.425855776541801, "STELARA": 1.0946742525497788, "TOUJEO": 10.82765539844747, "TRACLEER": 11.960816242960972, "TREMFYA": 11.79705175260848, "null": 1.7194937990892636}
\ No newline at end of file
+{"APTIVUS": 2636.088350718861, "ARANESP": 38.944273764033376, "null": 0.9270549370730904}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2404.json
index 70de72c1a9d..0b1feaad76f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2404.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2404.json
@@ -1 +1 @@
-{"APIDRA": 149.2685631211664, "BETAFERON": 29.42985552102633, "INSULIN": 15.366393445326151, "LANTUS": 181.95344867559004, "TOUJEO": 243.5743004184508}
\ No newline at end of file
+{"VAXZEVRIA": 2.169602818666696, "null": 0.5637527582657493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2405.json
index 28a19ae3a1b..00be7e3fa1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2405.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2405.json
@@ -1 +1 @@
-{"null": 8.518300179610732}
\ No newline at end of file
+{"ATRIPLA": 0.4319025597078523, "CANCIDAS": 18.21437716595152, "CELLCEPT": 3.764532078750252, "COMIRNATY": 0.0460864411437888, "ELIQUIS": 2.000282957041724, "IRBESARTAN": 22.00405209910552, "KEPPRA": 6.620489645626279, "KISQALI": 11.223199500063604, "MEKINIST": 4.74789447301703, "METHOTREXATE": 2.6996973640123416, "NORVIR": 34.658507580573975, "PEGASYS": 1.3263430016780826, "STIVARGA": 5.177619804681565, "VFEND": 6.7742683819065554, "VOTRIENT": 3.2183904173091102, "null": 1.2044010262245262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2406.json
index 9931662ba42..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2406.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2406.json
@@ -1 +1 @@
-{"OPSUMIT": 10.189654006060865, "TRACLEER": 9.672664379727996, "null": 2.5249763183370035}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2407.json
index beb21bfad8d..b35ce7c047d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2407.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2407.json
@@ -1 +1 @@
-{"null": 3.1582598847212897}
\ No newline at end of file
+{"DEXAMETHASONE": 63.39164132231778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2408.json
index 4a3aeb8d022..5e748a57746 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2408.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2408.json
@@ -1 +1 @@
-{"IBUPROFEN": 62.91403230198443, "null": 4.717673034412784}
\ No newline at end of file
+{"DEXAMETHASONE": 259.1929187695648, "null": 0.569459501492322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2409.json
index 79412b1ee3a..9af4d4f7fea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2409.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2409.json
@@ -1 +1 @@
-{"null": 8.413232666285767}
\ No newline at end of file
+{"null": 0.9168832868732756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/241.json
index 4e80803c53a..bb77bed2e24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/241.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/241.json
@@ -1 +1 @@
-{"ACETYLSALICYLIC": 57.00408155795449, "ADALIMUMAB": 20.490149599971677, "AIMOVIG": 3.8754338835926543, "APIDRA": 2.880010058198766, "APREMILAST": 12.46491837827897, "ARAVA": 1.6724955679451017, "COMBIVIR": 2.0468256303664703, "COMIRNATY": 1.1076914955006614, "CYMBALTA": 1.3876616934237536, "ENBREL": 1.9041130525660308, "GARDASIL": 1.2823919529159238, "HIZENTRA": 2.6565860649088613, "HUMIRA": 1.0068696776341275, "INSULIN": 3.798263650133136, "IRON": 6.509293080257265, "KEYTRUDA": 1.178861093604889, "LANTUS": 5.15604615970874, "NEXAVAR": 1.451790831923561, "PANTOPRAZOLE": 1.8802249392906167, "PIRFENIDONE": 48.55819001664136, "RILUTEK": 52.27602465770154, "SHINGRIX": 2.345142765917581}
\ No newline at end of file
+{"COMIRNATY": 6.05886582624056, "SPIKEVAX": 0.7502411442718391, "VAXZEVRIA": 0.5837999673271357, "null": 0.3033215444037555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2410.json
index c6c17758177..cee5510a291 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2410.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2410.json
@@ -1 +1 @@
-{"ASPARAGINASE": 39.01901747401963, "QARZIBA": 3928.132134634512}
\ No newline at end of file
+{"ABILIFY": 0.2649195513151987, "ABRAXANE": 2.494823195421424, "ACLIDINIUM": 3.005973076695175, "ADALIMUMAB": 0.2305013592333001, "ADCIRCA": 1.3044653045430126, "AFINITOR": 2.1385206277187554, "AIMOVIG": 0.2569919161668857, "ALIMTA": 2.0837567409464275, "AMBRISENTAN": 8.144903209767634, "ANAKINRA": 1.694505173460152, "ANIDULAFUNGIN": 6.978286938413132, "APIDRA": 0.9196181128745156, "APIXABAN": 0.5888453044999739, "ARANESP": 0.7813698475597939, "ARAVA": 0.2724439571170012, "ARIPIPRAZOLE": 3.0777886643549137, "ASPARAGINASE": 5.528754799572482, "ATRIPLA": 0.0505279797762645, "AUBAGIO": 1.0549963591059957, "AVANDIA": 0.3534340995328001, "AVASTIN": 0.4662731513156752, "AXICABTAGENE": 6.827100509368127, "AZACITIDINE": 1.569782014897046, "AZATHIOPRINE": 1.6818851284603966, "BENLYSTA": 2.804685630571506, "BETAFERON": 4.31690922074272, "BEXSERO": 3.8391068811057782, "BIKTARVY": 0.7083425726407506, "BOSULIF": 1.377216616483958, "BRAFTOVI": 0.6284018542235831, "BUDESONIDE": 0.9512742603387456, 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1.1828168259294207, "ENBREL": 1.240178094005112, "ENOXAPARIN": 0.8495688877949734, "ENTRESTO": 0.6227354024175842, "ENTYVIO": 2.259949468186108, "EPADERM": 51.347739721160735, "ERLEADA": 1.1766632273000996, "ESBRIET": 0.6429800472484234, "EVENITY": 1.3893823236023255, "EXFORGE": 0.4199830830783819, "EXJADE": 1.3499038860723476, "FAMPYRA": 0.5110938202315429, "FASENRA": 1.0837048539203222, "FASLODEX": 1.502243766420665, "FEBUXOSTAT": 2.1137575478070527, "FENTANYL": 0.6582908751172125, "FIRDAPSE": 1.7426554427124392, "FORSTEO": 0.3390915257216889, "FORXIGA": 0.622753498071328, "GANCICLOVIR": 0.975485585484368, "GARDASIL": 1.532875016064186, "HALAVEN": 1.062048877293865, "HARVONI": 0.6041123645911352, "HERCEPTIN": 1.079100114572049, "HIZENTRA": 5.16096964056848, "HUMALOG": 1.4875377606202616, "HUMIRA": 1.808347405275578, "HYQVIA": 3.290806022163914, "IBRANCE": 2.448382365084096, "ILARIS": 29.26234992616037, "IMBRUVICA": 3.311907246670537, "INCIVO": 1.1299693414932084, "INLYTA": 0.7811274595061777, "INSULIN": 0.8979603938955381, "INVOKANA": 16.604928654713408, "IRESSA": 0.5725379041335578, "JAKAVI": 0.8418038329673256, "JANUMET": 1.0140933579595597, "JANUVIA": 1.4075027253187944, "JARDIANCE": 1.3648977367088782, "JEVTANA": 3.11699386572926, "KALETRA": 0.5890340102899513, "KEPPRA": 0.093325603713939, "KEYTRUDA": 0.7051964193124809, "KYMRIAH": 0.5176248530830779, "LANTUS": 1.2600891187012129, "LATUDA": 0.4244988646966091, "LEFLUNOMIDE": 2.678123215448173, "LEVEMIR": 1.6787779594344407, "LEVETIRACETAM": 0.2674782308145572, "LEVOFLOXACIN": 0.3196633977103448, "LYRICA": 1.007526963493505, "MABTHERA": 1.1961668638173628, "MEKINIST": 1.165179925787606, "MELATONIN": 1.4210331859883183, "MENVEO": 14.478336598434163, "MEPOLIZUMAB": 1.6901914912237022, "MERCAPTOPURINE": 1.955424316773701, "METFORMIN": 1.9781401369051217, "METHOTREXATE": 2.550685685509565, "MMRVAXPRO": 0.3619090764576388, "MODERNA": 0.3221112422933676, "MYCOPHENOLATE": 0.8216675497355396, "NEULASTA": 1.13803213292662, "NEXAVAR": 0.368603731688778, "NOT": 1.5538145704320117, "NPLATE": 1.8025373044161936, "NUCALA": 0.8856202796137829, "OLANZAPINE": 0.2547321328668671, "OMALIZUMAB": 2.8707600745308866, "OPDIVO": 0.6643476759169076, "OPSUMIT": 2.383905008592559, "OPTIMARK": 1.5732967505652418, "ORENCIA": 5.029757500939479, "PEGASYS": 2.1801629576672634, "PEGINTERFERON": 1.7006676671002432, "PEGINTRON": 2.522573468139489, "PEMBROLIZUMAB": 1.056751394232203, "PEMETREXED": 1.1255990102801852, "PLAVIX": 0.4851966725687793, "PLEGRIDY": 0.6206449618671708, "PREVENAR": 1.657456116043996, "PRIVIGEN": 0.5814301627997104, "RAPAMUNE": 2.4725576547401005, "REMICADE": 5.536573011993927, "REVATIO": 1.592352519953091, "REVLIMID": 1.5652034094357616, "RIBAVIRIN": 0.4173279965666485, "RINVOQ": 2.666736030245744, "RITUXIMAB": 2.468292148659837, "ROACTEMRA": 6.72720075301463, "SAXENDA": 0.3587293784223344, "SHINGRIX": 4.503125644263784, "SIMPONI": 5.3438987518508, "SOLIRIS": 2.538291894183596, "SOMAVERT": 10.484020847367836, "SPIKEVAX": 0.5273850241670278, "SPRYCEL": 2.1109676609757853, "STELARA": 3.827688036398963, "STIVARGA": 0.2565238037326588, "SUBOXONE": 0.7447764264516789, "SUTENT": 0.8490464407154212, "TASIGNA": 1.2370150046494237, "THALIDOMIDE": 1.782740555782903, "TIVICAY": 1.9865113966315515, "TOCILIZUMAB": 7.713518262586139, "TOUJEO": 0.9182915878328448, "TOVIAZ": 0.6458003924470218, "TOZINAMERAN": 1.1498639272285052, "TRACLEER": 1.9086092257487148, "TRELEGY": 0.4728974446591775, "TREMFYA": 6.413235889914261, "TRUVADA": 0.051191390182188, "VAXZEVRIA": 0.4444701943977228, "VELTASSA": 2.204686974173617, "VFEND": 0.462897034453094, "VICTOZA": 0.8036548426292419, "VOTRIENT": 0.5752431278603132, "VYXEOS": 9.518420207280547, "XELJANZ": 3.846331673715104, "XOFIGO": 1.180743114605603, "XOLAIR": 0.6621926448778911, "XTANDI": 0.9421170288301244, "YERVOY": 1.3207488962353904, "ZOMETA": 2.6517937366580027, "ZOSTAVAX": 5.230657537607242, "ZYPREXA": 1.6073370608186388, "null": 0.8666642735957595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2411.json
index ebf5b4d79b5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2411.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2411.json
@@ -1 +1 @@
-{"ADCIRCA": 16.910098237378843, "ADEMPAS": 6.592508650715661, "ALEMTUZUMAB": 2.451565360099706, "ASPARAGINASE": 2.736999805130599, "AVASTIN": 4.940960810797854, "BORTEZOMIB": 5.462717866926816, "BUSULFAN": 8.281061265787423, "CELLCEPT": 2.03200452509942, "CICLOSPORIN": 2.1714254147972483, "CINRYZE": 19.926846416457927, "CUBICIN": 13.796878362177525, "CYTARABINE": 3.0422651673140653, "DOCETAXEL": 3.8409877748685113, "ENTYVIO": 1.365000714254962, "EXJADE": 4.365029135129989, "FORSTEO": 1.1944907559139308, "IBRANCE": 1.163700358047114, "KEYTRUDA": 2.6907005772513277, "METHOTREXATE": 1.2269842623703748, "NAGLAZYME": 28.215620515878587, "OPSUMIT": 15.88712741232774, "OPTIMARK": 2.2342150366310363, "PRIVIGEN": 2.9943085932331317, "REVATIO": 4.758317415666881, "REVESTIVE": 208.10931976215815, "RITUXIMAB": 1.6654531814228626, "ROACTEMRA": 8.41545010273417, "RUCONEST": 30.379321726271023, "SIMPONI": 3.253362844794878, "SOLIRIS": 18.38374204773497, "SPINRAZA": 4.573279179665016, "STELARA": 1.1890626611569008, "TRACLEER": 10.561521861526485, "VFEND": 2.1858518328362457, "XELJANZ": 1.9258348873850155, "XTANDI": 1.9120429674887385, "null": 1.1506140886924672}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2412.json
index dcda24aee08..e2a2f64e786 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2412.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2412.json
@@ -1 +1 @@
-{"BEDAQUILINE": 36.35403431090956, "BORTEZOMIB": 27.551091710468608, "CICLOSPORIN": 3.856704800362588, "MIDAZOLAM": 18.09468777224527, "OPSUMIT": 16.412946276396884, "SOLIRIS": 10.222546515519932, "TRACLEER": 13.396763461393135}
\ No newline at end of file
+{"IRESSA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2413.json
index 63055300ac2..fe8b4dd88fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2413.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2413.json
@@ -1 +1 @@
-{"ANGIOX": 252.83703855717584, "AVASTIN": 19.51913886594531, "ELIQUIS": 3.197149907745068, "NOVOSEVEN": 73.5638634286628, "null": 1.112199150955557}
\ No newline at end of file
+{"JARDIANCE": 101.27862142477788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2414.json
index b0f488ba817..7fcb14b6989 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2414.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2414.json
@@ -1 +1 @@
-{"null": 4.705583054188087}
\ No newline at end of file
+{"null": 0.8265660265104664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2415.json
index 15574012c4f..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2415.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2415.json
@@ -1 +1 @@
-{"null": 4.406448101978552}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2416.json
index 154932acfb3..7a6f94bc4e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2416.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2416.json
@@ -1 +1 @@
-{"AIMOVIG": 11.108017685912287, "AZILECT": 64.0807080143582, "FORSTEO": 3.779206077775167, "INCRUSE": 32.54899279044496, "NEULASTA": 65.49996930188465, "TRELEGY": 15.654731615164293, "null": 4.719271362286081}
\ No newline at end of file
+{"null": 0.5481849683427173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2417.json
index 0f2103183fd..8bf367bb239 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2417.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2417.json
@@ -1 +1 @@
-{"AIMOVIG": 2.616855563620365, "APIDRA": 9.380587072768376, "BYDUREON": 17.534758389233602, "BYETTA": 3.625350070257985, "EYLEA": 217.316309397297, "FASENRA": 28.55691187999221, "INSULIN": 6.406533331932971, "LANTUS": 10.727584409550742, "SIMPONI": 6.145832038581172, "null": 2.5091401113766705}
\ No newline at end of file
+{"null": 0.8927233659844568}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2418.json
index c971929c536..778f4aad1f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2418.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2418.json
@@ -1 +1 @@
-{"null": 4.386797935305641}
\ No newline at end of file
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2419.json
index d80cc33f176..f45524a2e2a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2419.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2419.json
@@ -1 +1 @@
-{"null": 3.0265595087464576}
\ No newline at end of file
+{"null": 2.790893158746566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/242.json
index 53ac4766961..b868b424c59 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/242.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/242.json
@@ -1 +1 @@
-{"CICLOSPORIN": 24.17064032327501}
\ No newline at end of file
+{"null": 3.521488923428598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2420.json
index e55f3e6fc05..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2420.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2420.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 2.223835925107398, "FENTANYL": 3.220891315573557, "JARDIANCE": 1.338199193623265, "KEYTRUDA": 1.305863646679443, "MIDAZOLAM": 10.111722140553178, "OLANZAPINE": 3.785527016663176, "RELVAR": 16.073984553197953, "TEMOZOLOMIDE": 61.41906402176815, "VFEND": 3.328160182644789, "ZYPREXA": 3.4326556602616947, "null": 2.7536556613705887}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2421.json
index 2ece9c1814a..9110c55a8e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2421.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2421.json
@@ -1 +1 @@
-{"ABILIFY": 7.160985152346186, "ACTOS": 1.729299222709386, "ADVAGRAF": 2.8074198527320195, "AFINITOR": 4.081175119782228, "ALL": 2.733659929445376, "ALPELISIB": 6.287278265310076, "AMIKACIN": 1.0182938124512264, "AMINOSALICYLIC": 1.571562194636272, "ARANESP": 14.592634890733809, "ARIPIPRAZOLE": 1.5432331447259164, "ASPARAGINASE": 1.0412719576835447, "AUBAGIO": 1.102922326572837, "AVAMYS": 1.5419741770602404, "AVANDIA": 1.4578999116195972, "AZATHIOPRINE": 1.1058118353774713, "BARACLUDE": 1.6732961697466258, "BELIMUMAB": 2.205510694192626, "BIKTARVY": 3.305771177309938, "BOSULIF": 1.9487527976615453, "BUDESONIDE": 1.1399591813258514, "BYDUREON": 1.9648727360204208, "BYETTA": 1.4054550816550588, "CANAGLIFLOZIN": 25.52477491856165, "CELLCEPT": 2.5526158166559805, "CHAMPIX": 1.3830591447581806, "CIALIS": 1.1524759942761182, "CICLOSPORIN": 1.4069742772456049, "COAPROVEL": 2.5861781551644336, "COMBIVIR": 1.6664445411640412, "CRIXIVAN": 10.581201166072963, "CYMBALTA": 1.0174708118404738, "DAKLINZA": 1.323816400166324, "DAPAGLIFLOZIN": 6.386148070055702, "DARBEPOETIN": 11.719148574124294, "DESCOVY": 2.849910795103178, "EFAVIRENZ": 1.2004379053999237, "ELIQUIS": 1.20429030795534, "EMTRICITABINE": 1.173445110700834, "ENBREL": 1.0975780409712443, "ENTRESTO": 1.9962448190623785, "EPIVIR": 8.010185872004477, "EUCREAS": 1.329763279463102, "EVEROLIMUS": 2.82404467931253, "EXFORGE": 6.65583738335543, "FORTOVASE": 8.072037215031001, "FORXIGA": 1.5626468066256636, "FULVESTRANT": 1.4114733732858111, "GALVUS": 5.565848531106048, "GLIBENCLAMIDE": 2.577830737863397, "HUMALOG": 1.6697373799767246, "HUMIRA": 1.439884073930524, "IBRANCE": 1.8865031219253887, "IMATINIB": 1.5800436255500625, "INCRUSE": 2.021314823318044, "INLYTA": 1.7283823595937542, "INSULIN": 1.6723399294225565, "INTRONA": 7.882482432473407, "INVIRASE": 13.702374618233254, "IPILIMUMAB": 2.712612978953228, "IRBESARTAN": 1.2643946864504474, "IRON": 1.1182430534500347, "ISENTRESS": 1.9738456962344528, "ISOPHANE": 5.676870603236688, "JANUMET": 2.9373070610461123, "JANUVIA": 3.305050453022337, "JARDIANCE": 1.2706487128631645, "KAFTRIO": 1.1786491715585996, "KALETRA": 1.3577184199737666, "KEYTRUDA": 2.0431317467690926, "LANTUS": 1.5340270591481493, "LATUDA": 2.2540518432200427, "LEFLUNOMIDE": 1.6194912910955843, "LYRICA": 2.8729574806089, "MELATONIN": 1.6398282982680723, "METFORMIN": 1.506843005311594, "METHOTREXATE": 1.0785311565363884, "MYCOPHENOLATE": 1.1109790332137026, "NILOTINIB": 2.232325302117588, "NORVIR": 1.2893423084122742, "NOT": 1.4015379988176015, "NUCALA": 1.2771820331418828, "OLANZAPINE": 3.1691932370526965, "OMALIZUMAB": 1.899727643220672, "ONGLYZA": 4.606209068461874, "OPDIVO": 1.793971826620877, "PASIREOTIDE": 53.81031866087957, "PEGASYS": 2.036904087521839, "PEGINTERFERON": 1.1136995809217476, "PEGINTRON": 4.677338784516457, "PEMBROLIZUMAB": 1.9042443098765955, "PIQRAY": 9.45279038400892, "PLEGRIDY": 1.0059400050146114, "RANOLAZINE": 4.661594047273731, "RAPAMUNE": 4.2154013296973, "RASILEZ": 3.525906977290141, "REBETOL": 1.6234702459049697, "REVATIO": 1.4561596614079175, "REYATAZ": 2.6803133827910326, "RIBAVIRIN": 1.914912012107828, "RITUXIMAB": 1.2242524836483222, "SIGNIFOR": 29.916075994128832, "SITAGLIPTIN": 7.759073765927343, "SKYRIZI": 1.177298401553455, "SOMATROPIN": 5.843430255987122, "STELARA": 1.5633315478915175, "SUTENT": 1.0414367243471152, "TACROLIMUS": 1.9984429643089583, "TASIGNA": 5.095826424126925, "TIVICAY": 1.7194649012297687, "TORISEL": 3.2700989986205378, "TOVIAZ": 1.7188878585518477, "TRELEGY": 2.3371442802411524, "TREMFYA": 1.0766713536023758, "TRIUMEQ": 2.7495817701500176, "VALSARTAN": 3.10409808225989, "VELTASSA": 1.401494530828655, "VIAGRA": 9.954056173480808, "XELJANZ": 2.486357079201282, "XOLAIR": 1.236701886894928, "ZOSTAVAX": 2.335580625021749, "ZYPREXA": 27.945370773614137, "null": 1.1053369689316208}
\ No newline at end of file
+{"ASPARAGINASE": 107.35954956553772, "BUSULFAN": 27.26437871188312, "KEYTRUDA": 15.64901358126814, "MITOTANE": 1979.9628794670311, "OPDIVO": 26.05312368843499, "SUTENT": 2.739832016658553, "null": 0.689726462010479}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2422.json
index 3606612c1de..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2422.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2422.json
@@ -1 +1 @@
-{"ABASAGLAR": 13.576814997310883, "ACTOS": 10.314417524568984, "ACTRAPID": 11.34641026278777, "ALISKIREN": 16.3668090258124, "APIDRA": 35.97878951050089, "AVANDAMET": 1.564686814534568, "AVANDIA": 1.4837767990141058, "BYDUREON": 4.751849708131042, "BYETTA": 7.847008794553672, "CORTICOSTEROID": 10.742450278118293, "DAPAGLIFLOZIN": 20.027312144058687, "DENOSUMAB": 2.9057128299904025, "DULAGLUTIDE": 10.528916639845542, "EMPAGLIFLOZIN": 3.97884509518968, "EUCREAS": 6.844122069330457, "FIASP": 16.224442829860095, "FORXIGA": 5.2130056582385285, "GALVUS": 9.686584580573502, "GLIBENCLAMIDE": 8.447044086679902, "HUMALOG": 14.30079560171121, "INSULATARD": 45.73221546366466, "INSULIN": 31.442923526123764, "INSUMAN": 21.62515435482284, "INVOKANA": 9.360549912086556, "ISOPHANE": 7.786595303256626, "JANUMET": 22.949770282321506, "JANUVIA": 19.180688467661472, "JARDIANCE": 2.068517325159802, "KAFTRIO": 1.0112116560856743, "LANTUS": 34.88167805070266, "LEVEMIR": 28.45367603973401, "LIRAGLUTIDE": 17.822798755797912, "METFORMIN": 46.19856862577995, "MIXTARD": 24.90666304953643, "NOVOMIX": 38.6016981657808, "NOVONORM": 16.849524671917386, "NOVORAPID": 22.655253030706724, "OMALIZUMAB": 1.380757945515093, "OPTISULIN": 140.78213247575314, "PASIREOTIDE": 15.64736701682251, "ROSIGLITAZONE": 8.764515565412617, "RYBELSUS": 7.759231661479383, "SITAGLIPTIN": 24.894974495762845, "TOUJEO": 73.25068238530734, "TRESIBA": 27.95744980032748, "TRULICITY": 6.013370393474809, "VICTOZA": 11.58427270641132, "VILDAGLIPTIN": 17.407003863466525, "ZOSTAVAX": 1.329088047074631, "ZYPREXA": 2.2571293419371847}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2423.json
index 99cc529eb61..04cf38c411b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2423.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2423.json
@@ -1 +1 @@
-{"HUMALOG": 85.2915186896516}
\ No newline at end of file
+{"CANCIDAS": 362.8002460586913, "CASPOFUNGIN": 574.5119028097828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2424.json
index 636a496553b..d8028c9c0fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2424.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2424.json
@@ -1 +1 @@
-{"ACTRAPID": 58.117475163788185, "APIDRA": 16.647019762471544, "FORXIGA": 6.733549963189873, "HUMALOG": 28.60281995299111, "INSULIN": 11.622247042035267, "JARDIANCE": 5.371521900967745, "LANTUS": 19.47879019768367, "LEVEMIR": 23.696570480335687, "MIXTARD": 46.458681894083526, "NOVORAPID": 4.533220415054642, "OLANZAPINE": 1.589480680990533, "PEGINTRON": 1.5882993847639575, "ZYPREXA": 49.46844437744479}
\ No newline at end of file
+{"null": 0.3553960383272238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2425.json
index 0d3f517ea46..be5c830220d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2425.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2425.json
@@ -1 +1 @@
-{"AVANDIA": 3.221978887693275, "HUMALOG": 35.37550111586806, "INSULIN": 21.564700287283827, "JANUMET": 49.57003998749576, "JANUVIA": 40.179247410170674, "JARDIANCE": 1.826552513734936, "LANTUS": 15.237083892737688, "LEVEMIR": 15.972291042383242, "TRULICITY": 6.540771285488041, "ZOSTAVAX": 1.9199692819571907, "ZYPREXA": 3.612306794849199}
\ No newline at end of file
+{"CYTARABINE": 17.78686887311397, "null": 0.6463740120527536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2426.json
index 2df2a8c76bb..0c866ce13a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2426.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2426.json
@@ -1 +1 @@
-{"CIMZIA": 10.137098243849817, "HUMALOG": 32.44745844754265, "LANTUS": 11.68373358423876}
\ No newline at end of file
+{"COMIRNATY": 1.8564753312204765, "GARDASIL": 9.508103438573952, "SPIKEVAX": 0.5409012169408958, "VAXZEVRIA": 0.7322855802453225, "null": 0.213927940354013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2427.json
index 528fb3d9577..d1fa25a25bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2427.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2427.json
@@ -1 +1 @@
-{"ACTRAPID": 22.56599025086869, "EMPAGLIFLOZIN": 33.98247064535207, "EXFORGE": 4.855677195260501, "FORXIGA": 7.420458825835947, "HUMALOG": 23.94745638444631, "INSULIN": 27.47775794054949, "INVOKANA": 349.4085678851333, "JARDIANCE": 13.556308451523613, "LANTUS": 14.29528794394822, "LEVEMIR": 20.344386665350797, "MICARDIS": 7.003755022381172, "MIXTARD": 85.83869103505633, "NOVORAPID": 7.206626437068032, "ZOSTAVAX": 2.1623559715197254, "ZYPREXA": 2.969149638576205}
\ No newline at end of file
+{"ABACAVIR": 1.9005268212855229, "AFINITOR": 2.432287287259083, "ALEMTUZUMAB": 8.664859486412732, "AUBAGIO": 17.894694885581256, "AZATHIOPRINE": 3.0406904016815046, "BENZODIAZEPINES": 69.14503867357573, "BUPRENORPHINE": 2.803498177684689, "BUSULFAN": 3.712340001241087, "CICLOSPORIN": 7.931049632264671, "COMIRNATY": 0.2003913392539123, "CYMBALTA": 0.4417222378478906, "CYTARABINE": 2.580033639044916, "DEXAMETHASONE": 5.155574870203503, "EFAVIRENZ": 10.886206501339606, "FAMPYRA": 8.342384960998306, "GARDASIL": 0.8200321918350771, "GILENYA": 101.42805789536058, "IBUPROFEN": 2.3132078356378023, "KEPPRA": 1.7224656873009632, "KESIMPTA": 14.729543421403823, "LAMIVUDINE": 9.040011859027077, "LANTUS": 0.5154699215044912, "LEMTRADA": 17.332577848127862, "LEVETIRACETAM": 1.9321107313852688, "LYRICA": 2.038684290983202, "MAVENCLAD": 10.425797244975628, "MEKINIST": 11.909180653404128, "METHOTREXATE": 1.7209878177587978, "NEXAVAR": 0.889152771043834, "PEMBROLIZUMAB": 5.045058277188986, "PLEGRIDY": 9.475718423097147, "SIMPONI": 1.187858816230427, "SOLIRIS": 1.5487735376217742, "SPIKEVAX": 0.1754827833743017, "STELARA": 0.7459214142129518, "SUTENT": 0.7658356011242952, "TOZINAMERAN": 0.3309519165998828, "VAXZEVRIA": 0.1358462430536735, "null": 0.6469675813086396}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2428.json
index 85d188895b2..ad474024b82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2428.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2428.json
@@ -1 +1 @@
-{"HUMALOG": 12.773037820135862, "INVOKANA": 1113.6493314067463, "JARDIANCE": 8.244784523169459, "LANTUS": 5.339476095327995}
\ No newline at end of file
+{"BLINCYTO": 669.3600734530287, "CYTARABINE": 35.37615033599663, "ICLUSIG": 159.99395438148198, "KYMRIAH": 89.18146417743372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2429.json
index a752e5cdae9..dc56c7c35cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2429.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2429.json
@@ -1 +1 @@
-{"HUMALOG": 21.28346852925818}
\ No newline at end of file
+{"BENLYSTA": 133.52816334255775}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/243.json
index 59ae73d7273..314e55022cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/243.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/243.json
@@ -1 +1 @@
-{"null": 1.1737962749137685}
\ No newline at end of file
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2430.json
index c8d959d5ac1..fd4de31f3e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2430.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2430.json
@@ -1 +1 @@
-{"HUMALOG": 21.033150799084908}
\ No newline at end of file
+{"ALEMTUZUMAB": 23.96100733902436, "CELLCEPT": 30.663042713454995, "CICLOSPORIN": 22.66235708916217, "CYTARABINE": 80.22808013371929, "DOXORUBICIN": 27.93473138313545, "EPIVIR": 38.90920211271096, "KYMRIAH": 26.42000969427001, "METHOTREXATE": 24.438645404962084, "RITUXIMAB": 21.994671352109517, "null": 0.1358781079609176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2431.json
index f169b5f21ef..b783b8a5f79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2431.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2431.json
@@ -1 +1 @@
-{"ACTRAPID": 121.4428010700712, "APIDRA": 14.604165075366192, "HUMALOG": 22.078109391635746, "LANTUS": 38.245322027732605, "LEVEMIR": 30.04175447263743, "NOVORAPID": 39.17742908418572, "ZYPREXA": 6.794034007900975}
\ No newline at end of file
+{"METHOTREXATE": 1228.7031614813045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2432.json
index da21a08256f..dbd5b1d805c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2432.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2432.json
@@ -1 +1 @@
-{"ZYPREXA": 75.06022336659977}
\ No newline at end of file
+{"null": 0.8179166441563179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2433.json
index 547f1a42d2c..08506371faa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2433.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2433.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.1122511686741627, "ACTOS": 9.57211123719186, "ACTRAPID": 6.956915140463213, "ALPELISIB": 13.721487383478536, "APIDRA": 10.414905369798202, "ASPARAGINASE": 1.0586983683101294, "BYDUREON": 3.130921618612218, "BYETTA": 2.107470548018147, "CANAGLIFLOZIN": 29.23219617567595, "CRIXIVAN": 3.283379577189858, "DAPAGLIFLOZIN": 25.858499878737284, "DULAGLUTIDE": 9.271060300581452, "EMPAGLIFLOZIN": 89.44592024531175, "EUCREAS": 1.7501453058857843, "FIASP": 14.361551521574516, "FORXIGA": 54.43984167908836, "GLUCAGON": 4.34660284657334, "HUMALOG": 19.34999277705633, "INSULATARD": 8.997746470177342, "INSULIN": 11.00435716352555, "INVIRASE": 4.30234548388804, "INVOKANA": 245.70819420025737, "IPILIMUMAB": 6.098810213645955, "JANUMET": 1.237738033501541, "JANUVIA": 1.2586834447165451, "JARDIANCE": 129.53236033856984, "KEYTRUDA": 3.359984543708683, "LANTUS": 7.140469382423087, "LEVEMIR": 18.388140824666596, "MIXTARD": 27.385474127679416, "NOVOMIX": 12.350700832129338, "NOVORAPID": 46.18896473969487, "OLANZAPINE": 2.634341098214647, "OPDIVO": 3.257024816621925, "PEGINTRON": 1.8813537216188931, "PEMBROLIZUMAB": 5.312508188414273, "PIQRAY": 18.280216893171648, "RYBELSUS": 3.6290865816322255, "TOUJEO": 3.78987716326205, "TRESIBA": 16.455383706552617, "TRULICITY": 4.007679780105471, "VICTOZA": 4.578475012706931, "ZYPREXA": 9.708810155299544}
\ No newline at end of file
+{"null": 2.796596211809002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2434.json
index ad1240b37e5..7fd4b9997ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2434.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2434.json
@@ -1 +1 @@
-{"HUMALOG": 18.37649268819292, "NOVORAPID": 39.75700705592475}
\ No newline at end of file
+{"CELLCEPT": 8.671620104057371, "COMIRNATY": 0.4953157859388325, "DEXAMETHASONE": 7.53853412402397, "GARDASIL": 3.7601409626398254, "VAXZEVRIA": 0.1986442762126326, "null": 0.7798570097421728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2435.json
index 833d3a9d256..0b417b8452b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2435.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2435.json
@@ -1 +1 @@
-{"EMPAGLIFLOZIN": 52.805590231642086, "FORXIGA": 103.26586684387912, "HUMALOG": 8.862039809632307, "JARDIANCE": 35.219671564422946, "KEYTRUDA": 3.270607604992777, "LANTUS": 2.68361910625482, "LEVEMIR": 18.22546555655237, "NOVORAPID": 51.01979435211996, "PEGINTRON": 6.195044171748146, "ZYPREXA": 15.38794202383344}
\ No newline at end of file
+{"AVAMYS": 15.760393057132534, "BUDESONIDE": 5.220533402869922, "ENTYVIO": 51.14236294057951, "HYDROCORTISONE": 26.30084357726834, "null": 1.1433731701127874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2436.json
index db47558698b..3e6fb253dda 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2436.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2436.json
@@ -1 +1 @@
-{"APIDRA": 34.54838936392488, "DAPAGLIFLOZIN": 42.34912395885505, "FIASP": 34.569788537965614, "FORXIGA": 7.778886649909975, "GLIBENCLAMIDE": 35.260944383327974, "HUMALOG": 3.312638011997777, "INSULIN": 51.32322129283153, "JANUMET": 13.372696042377507, "JARDIANCE": 5.251119259200103, "LANTUS": 14.86399800377885, "LEVEMIR": 21.728037728530648, "NOVORAPID": 9.84286379241238, "TOUJEO": 43.04469094927012, "TRULICITY": 5.187875080257822}
\ No newline at end of file
+{"COMIRNATY": 0.4865134555391714, "CYMBALTA": 16.474063139931268, "OMALIZUMAB": 38.994538446611536, "null": 0.5029418867864726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2437.json
index 3adf115e334..05b1d02b7db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2437.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2437.json
@@ -1 +1 @@
-{"BYETTA": 10.601798627392656, "HUMALOG": 10.163761874487356, "INSULIN": 8.100042622105011, "JANUMET": 11.182808821009957, "JANUVIA": 8.874988575258415, "LANTUS": 8.231359648154577, "LEVEMIR": 8.541939893518224, "METFORMIN": 28.19550425164873, "MICARDIS": 9.56806342607366, "ZOSTAVAX": 8.178549837230154, "ZYPREXA": 10.300323979748224}
\ No newline at end of file
+{"BRAFTOVI": 22.94528027908625, "COBIMETINIB": 172.46883419062755, "COMIRNATY": 0.4850081021427601, "COTELLIC": 78.12012832584566, "SPIKEVAX": 0.255557544743013, "TOZINAMERAN": 0.9348449519678128, "VAXZEVRIA": 0.1389293521366677, "VIAGRA": 36.12022254020403, "null": 1.40083028813585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2438.json
index ea24f704774..15fba11169d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2438.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2438.json
@@ -1 +1 @@
-{"APIDRA": 9.022097189309632, "AVONEX": 38.56803408252614, "BYDUREON": 7.830225665618648, "BYETTA": 18.989934859311205, "CICLOSPORIN": 1.5051702411961934, "CYMBALTA": 1.4642348340750917, "ELIQUIS": 1.4595897934388973, "EMPAGLIFLOZIN": 8.688665250009107, "FORXIGA": 3.35204112246369, "HUMALOG": 18.282970033246286, "INSULIN": 11.159458266655582, "JANUMET": 19.49834522090172, "JANUVIA": 10.098974786103687, "JARDIANCE": 1.1156540758478584, "LANTUS": 12.52516731441894, "LEVEMIR": 12.64338406508318, "LEVETIRACETAM": 4.293904056210915, "LYRICA": 7.810944812397135, "PLAVIX": 1.4578413506591106, "TRULICITY": 4.413746809934038, "VIAGRA": 2.0076102337676547, "VICTOZA": 3.0294064947212456, "ZOSTAVAX": 12.945531658703144, "ZYPREXA": 19.57954386470773}
\ No newline at end of file
+{"BRILIQUE": 362.93471584802313, "BUPRENORPHINE": 14.57212305153528, "CYTARABINE": 22.8904238492737, "PRASUGREL": 484.4571737531444, "null": 0.889746739999042}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2439.json
index cfc981d74a7..d17e0723f15 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2439.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2439.json
@@ -1 +1 @@
-{"APIDRA": 74.65499416522792, "EYLEA": 124.92492918291546, "LANTUS": 7.864417791616733}
\ No newline at end of file
+{"null": 2.3677884548371746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/244.json
index 42779e7eefe..7ca13761f23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/244.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/244.json
@@ -1 +1 @@
-{"ALISKIREN": 133.22036544089312, "ARIPIPRAZOLE": 2.743349457086406, "BEDAQUILINE": 2.762911713375732, "BIKTARVY": 1.8642262426464216, "BRINTELLIX": 1.1822675605893174, "CHAMPIX": 6.418778886144247, "COMTAN": 3.74923040719733, "CYMBALTA": 98.92737723296162, "ESOMEPRAZOLE": 4.142772892000246, "INTRONA": 10.212844626797075, "IRBESARTAN": 2.239939030146136, "KAFTRIO": 2.6457417063892894, "KEPPRA": 4.184311819798195, "LATUDA": 1.5390596350379446, "LEVETIRACETAM": 5.242873019592547, "LURASIDONE": 25.37238668375416, "OLANZAPINE": 3.424144708205358, "PEGASYS": 1.6533594100786904, "PEGINTERFERON": 1.4846194152889176, "PEGINTRON": 2.0667101406331296, "RIBAVIRIN": 1.336143363829667, "ZYPREXA": 2.343477978976052}
\ No newline at end of file
+{"null": 8.547832751550363}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2440.json
index 736d3c34a7c..31ff6adae81 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2440.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2440.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 2.8563304883267358, "APIDRA": 25.62535292506332, "AVANDAMET": 6.479268986983397, "AVANDIA": 5.475881645653248, "BYETTA": 4.392459873595424, "COAPROVEL": 6.396099907645613, "EYLEA": 3.0100254670406428, "HUMALOG": 51.53453526429638, "INSULIN": 23.70068762808112, "JANUMET": 2.791674732385608, "JANUVIA": 7.688628401269162, "JARDIANCE": 1.4255313390072075, "LANTUS": 36.316652952061794, "LEVEMIR": 22.545218006903, "NOVORAPID": 9.194256592183038, "PEGINTRON": 1.20892147622502, "RYBELSUS": 12.878447252421928, "TRESIBA": 17.975350852567903, "TRULICITY": 7.79395430943083, "VIAGRA": 2.106208176336417, "VICTOZA": 7.660216272847081, "ZOSTAVAX": 4.281667516142378, "ZYPREXA": 3.491502538606862}
\ No newline at end of file
+{"ADCIRCA": 25.697394403942678, "EXJADE": 4.467796382445273, "FIRDAPSE": 34.560489657803785, "INTRONA": 23.25685931960968, "JANUMET": 6.005572355759472, "JANUVIA": 5.937037726718078, "KEYTRUDA": 5.071430058306771, "NEULASTA": 20.01993553939071, "OPSUMIT": 20.510200642158733, "RUCONEST": 167.16862441343702, "TRACLEER": 7.387664812756595, "null": 1.8927626548749303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2441.json
index 9614c7aaec0..090e5fbec5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2441.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2441.json
@@ -1 +1 @@
-{"ZOSTAVAX": 30.444960257871987}
\ No newline at end of file
+{"null": 2.458558709929028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2442.json
index e7a6772d8b6..cd8a8aa5c7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2442.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2442.json
@@ -1 +1 @@
-{"null": 2.654715123360537}
\ No newline at end of file
+{"null": 1.119567934549201}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2443.json
index 397d3ada6da..eafa6384376 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2443.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2443.json
@@ -1 +1 @@
-{"ABILIFY": 4.603195056511371, "ARANESP": 59.39546002226727, "AVANDIA": 1.6954682644995178, "AYESURBY": 963.4787142268171, "CELLCEPT": 1.9522020382622165, "CICLOSPORIN": 4.066594532207034, "ELIQUIS": 1.1371047485260977, "EXJADE": 6.654257335853846, "HUMALOG": 1.577427017227216, "JANUMET": 1.7046505630788011, "JANUVIA": 5.127136322397493, "JARDIANCE": 1.059848929778889, "LANTUS": 9.391337975736286, "LEVEMIR": 12.867675214138, "MIMPARA": 8.007333561418653, "NOVOSEVEN": 37.984717029716926, "OPSUMIT": 15.951529258930387, "SOLIRIS": 9.089613092822114, "SPRYCEL": 2.0407428764158344, "TRACLEER": 7.093199902209117, "VELTASSA": 180.3347499129436, "VOTRIENT": 2.6534595252971527}
\ No newline at end of file
+{"COMIRNATY": 0.8175416320602392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2444.json
index de59fb6c242..cb56c1775c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2444.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2444.json
@@ -1 +1 @@
-{"COMIRNATY": 2.2810738365682446, "COVID19": 2.037056053273354, "SPIKEVAX": 2.045932338497128, "TOZINAMERAN": 1.483486255943708}
\ No newline at end of file
+{"ALLI": 4682.721906056164, "null": 1.2726777194859027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2445.json
index 21ab6b2ddb6..3c4dc1a4b2a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2445.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2445.json
@@ -1 +1 @@
-{"METHOTREXATE": 11.402566925772032, "null": 1.2637840507202138}
\ No newline at end of file
+{"CYMBALTA": 15.579738767812554, "null": 1.5595324857006607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2446.json
index 5931dae1923..e328ec12380 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2446.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2446.json
@@ -1 +1 @@
-{"null": 1.7393786727536549}
\ No newline at end of file
+{"COMIRNATY": 0.1873206571138106, "GARDASIL": 3.200512348781104, "VAXZEVRIA": 0.1385462304656851, "null": 2.800597627031849}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2447.json
index 48243da2cff..f17fe6f2189 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2447.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2447.json
@@ -1 +1 @@
-{"null": 2.0212289754145263}
\ No newline at end of file
+{"KEPPRA": 3.1835256726183743, "OLANZAPINE": 4.4220978785175005, "null": 5.3922551684876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2448.json
index dc5d4c72e5c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2448.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2448.json
@@ -1 +1 @@
-{"null": 1.3208610798247866}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2449.json
index 84e640e77d6..cd8ecbf1e28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2449.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2449.json
@@ -1 +1 @@
-{"null": 1.017980813242261}
\ No newline at end of file
+{"CLOPIDOGREL": 8.89435614935851, "ELIQUIS": 17.671620588135244, "PLAVIX": 16.472509102429786, "null": 1.7529549235132995}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/245.json
index 2cbd3ed99e4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/245.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/245.json
@@ -1 +1 @@
-{"ABILIFY": 3.127977635794941, "AIMOVIG": 1.1834325127449876, "ARIPIPRAZOLE": 27.39554159687701, "AVAMYS": 5.059052774068652, "BIKTARVY": 8.379935378050146, "BLINDED": 109.6591311425823, "BRIVARACETAM": 15.975556950926018, "BRIVIACT": 48.848659447160486, "BUPRENORPHINE": 3.249911106346879, "CHAMPIX": 9.813886018239751, "COSENTYX": 1.1664763875708513, "CYMBALTA": 2.022214791681776, "DEXAMETHASONE": 1.013771862264101, "DULOXETINE": 8.703659211682718, "KAFTRIO": 13.553637059290477, "KEPPRA": 11.313819744117389, "LATUDA": 5.976906178180464, "LEVETIRACETAM": 7.737605801786861, "OLANZAPINE": 4.633541349463407, "PEGASYS": 2.073042001878912, "PEGINTRON": 1.423942878457617, "RIBAVIRIN": 2.300511666048243, "SUBOXONE": 2.5416264576307346, "TAMIFLU": 1.5572651868822027, "VIMPAT": 3.776545546033588, "ZOSTAVAX": 1.170942062127761, "null": 1.5336768072715987}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2450.json
index d51814ec96c..d017d6e458d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2450.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2450.json
@@ -1 +1 @@
-{"ABATACEPT": 1.184335904136517, "ABEMACICLIB": 3.853968209491729, "ABRAXANE": 1.4035794435301707, "ACCOFIL": 1.400546113813082, "ACLASTA": 1.119288887584029, "ADALIMUMAB": 1.0310025406154222, "ADCIRCA": 1.9118318492924, "ADEMPAS": 2.3559216030963017, "ADENURIC": 2.184277298427641, "ADVAGRAF": 2.29093532676425, "AERIUS": 1.10526607945124, "AFATINIB": 4.689983751911651, "AFINITOR": 1.8147749800878352, "AFLIBERCEPT": 5.481201479602504, "ALIMTA": 1.615642662687166, "ALOGLIPTIN": 1.3971039521775976, "ALPELISIB": 3.3534145963512763, "AMBRISENTAN": 1.4419989226984855, "AMGEVITA": 2.184398709408377, "ANTIBIOTICS": 1.1701368827548209, "ATEZOLIZUMAB": 2.467650857473803, "AUBAGIO": 2.180190942105717, "AVASTIN": 2.6271439529554184, "AVELUMAB": 4.0359957295032665, "AXITINIB": 4.926284280621987, "AZATHIOPRINE": 1.086585624295788, "BAVENCIO": 1.933826152152518, "BEVACIZUMAB": 2.963101034397626, "BEXSERO": 1.315746853690103, "BIKTARVY": 1.1021774851902792, "BINIMETINIB": 1.776485607299327, 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1.088984327731991, "KIVEXA": 1.2442882658589, "LEFLUNOMIDE": 1.317564669050606, "LENALIDOMIDE": 1.5204281407918645, "LENVATINIB": 1.412925009170403, "LENVIMA": 3.537950666911017, "LIBTAYO": 1.0015977603844388, "LIRAGLUTIDE": 1.0347151414698696, "LONSURF": 3.075102886713893, "LOPINAVIR": 3.3930337253476712, "LOPINAVIR/RITONAVIR": 10.615012529823211, "LUMYKRAS": 7.907430577262925, "LUPKYNIS": 1.4171271915398975, "LUTATHERA": 1.4937487459751393, "LUTETIUM": 1.9338754698216096, "LYNPARZA": 1.014346767154601, "LYSODREN": 1.6881190711625462, "MACITENTAN": 1.292142355680974, "MEKINIST": 1.0807435446252638, "MELPHALAN": 1.0084232968282203, "METFORMIN": 1.6189125463759757, "MICAFUNGIN": 1.1201210181716663, "MICARDISPLUS": 1.2838314443739836, "MIDOSTAURIN": 1.7399471395434112, "MIMPARA": 1.3357138007852154, "MISOPROSTOL": 1.5689152673358884, "MMRVAXPRO": 1.431342757637614, "MOUNJARO": 1.7863760297231095, "MULTAQ": 1.3807946505355255, "MVASI": 1.4353806118923562, "MYCOPHENOLATE": 1.0894542583861275, "NEPARVIS": 2.33088420474321, "NERATINIB": 19.895343130944795, "NERLYNX": 13.996441800009944, "NEXAVAR": 4.365043504982423, "NINLARO": 3.74869922322214, "NINTEDANIB": 3.1437602900644626, "NIVOLUMAB": 2.1930670218441155, "NORVIR": 1.2479971913389647, "NOVONORM": 1.2153290706086834, "NOXAFIL": 1.0010509291158836, "NUBEQA": 1.036790749134006, "OCTREOTIDE": 1.4427512331539916, "OFEV": 13.028577007205682, "ONIVYDE": 9.419824304962695, "ONTRUZANT": 8.289963517713689, "OPDIVO": 2.047321335303416, "OPSUMIT": 1.5215679318352444, "OSIMERTINIB": 1.8590723723444704, "OSSEOR": 1.8645176385987192, "OTEZLA": 2.9770304467694824, "OZEMPIC": 1.8678976443488675, "PACLITAXEL": 1.2975300599866784, "PANITUMUMAB": 2.895725298359987, "PANTOPRAZOLE": 1.2778540640803189, "PASIREOTIDE": 2.119854734739539, "PAXLOVID": 2.2100780189255773, "PAZOPANIB": 2.95250785084866, "PEGASYS": 1.045111161154462, "PEMBROLIZUMAB": 1.3458876821852948, "PERJETA": 4.829383774564465, "PERTUZUMAB": 3.242182744686482, "PIQRAY": 3.851986577253494, "PIRFENIDONE": 1.7047902326855435, "PREOTACT": 1.0948135938846464, "PREVENAR": 1.6815425693266397, "PROTELOS": 1.3286032308791385, "RAPAMUNE": 1.1114690244820875, "RAPISCAN": 1.2700921710441206, "REGORAFENIB": 2.809967493333536, "REMICADE": 1.0604550322549873, "REMSIMA": 4.914727876732181, "REPAGLINIDE": 1.3141234562281636, "REVESTIVE": 1.0690668595884067, "REVLIMID": 2.5010231672730545, "REZOLSTA": 2.5036642626190755, "RISTFOR": 11.158261065504544, "ROTARIX": 3.822300686128263, "ROTASHIELD": 2.6816781958229385, "ROTATEQ": 6.856920330073041, "RUBRACA": 1.3038353115582673, "RYBELSUS": 3.491907372613593, "RYDAPT": 2.0038783884467426, "SACITUZUMAB": 6.040365679768657, "SAXENDA": 3.076554733221867, "SELINCRO": 1.697600504659539, "SEMAGLUTIDE": 1.0970945322497967, "SIGNIFOR": 2.9543420369916387, "SILODYX": 1.97349649612873, "SITAGLIPTIN": 1.8095473480026083, "SOMAVERT": 1.2560657531671882, "SORAFENIB": 3.340768320133641, "SOTORASIB": 5.963991070516686, "SPRYCEL": 1.6393443494271325, "STALEVO": 1.773809282577837, "STIVARGA": 2.420094225011319, "SUNITINIB": 2.794456665558751, "SUTENT": 2.668875619308291, "SYMTUZA": 1.2035339446427984, "TAGRISSO": 3.4768139923517114, "TAMIFLU": 1.2175929522791709, "TARCEVA": 3.910977844504598, "TAXOTERE": 2.6104785225720466, "TEDUGLUTIDE": 1.4391756727195049, "TEGAFUR": 2.6546182154293465, "TEMSIROLIMUS": 1.6523286494506213, "TERIFLUNOMIDE": 1.6133663406958527, "THERAPEUTIC": 1.2843804092732505, "THIOTEPA": 1.6656198553561037, "TIGECYCLINE": 1.916638743098034, "TRAMETINIB": 1.447118580682858, "TRASTUZUMAB": 1.828574781621152, "TRIUMEQ": 1.3402541761769702, "TRODELVY": 7.70959129632048, "TRULICITY": 4.05986356883934, "TYGACIL": 2.3042208419744674, "UPTRAVI": 1.8066215223947373, "UROREC": 2.3992783814738616, "VANDETANIB": 2.817387163725226, "VECTIBIX": 2.542156724671877, "VEDOLIZUMAB": 1.5802675932693726, "VELCADE": 1.0541667845828149, "VELMETIA": 4.1894846799870615, "VELTASSA": 1.9216729561747024, "VEMURAFENIB": 1.164979046773504, "VENCLYXTO": 1.3845541456743158, "VERZENIOS": 8.472568939081697, "VICTOZA": 3.218254485630264, "VORTIOXETINE": 1.2524195598757015, "VOTRIENT": 3.738781885370754, "XALKORI": 1.9443450881434448, "XELJANZ": 1.1552495495167798, "XELODA": 5.185923765483005, "XERMELO": 8.022891568732133, "XOFIGO": 1.6104870607340516, "XTANDI": 1.3326150090435949, "YERVOY": 5.71360276227037, "ZALTRAP": 7.946974230389584, "ZARZIO": 1.1182961143021486, "ZAVESCA": 4.774237620715573, "ZELBORAF": 1.6430882045612163, "ZEPATIER": 1.3627881591766284, "ZIAGEN": 1.878300400634439, "ZOMARIST": 2.788207509449657, "ZYDELIG": 4.664401319104965, "ZYLLT": 1.6318871506409358, "null": 1.0197947989752545}
\ No newline at end of file
+{"BRILIQUE": 5.522738122794619, "CLOPIDOGREL": 14.615309496059316, "COMIRNATY": 0.2471368435203804, "EFIENT": 38.11089996078156, "ELIQUIS": 30.243564895638706, "EVENITY": 9.53038046414173, "LIXIANA": 26.738081360684, "NEXAVAR": 4.653300268645264, "PEGASYS": 2.882877143779838, "PLAVIX": 10.643714890325509, "SPIKEVAX": 0.1194387233019792, "SUTENT": 0.9066226350135986, "VAXZEVRIA": 0.060518283756978, "XARELTO": 10.04960361465968, "null": 1.388104801929017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2451.json
index f4706b3f862..487e5ff0e02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2451.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2451.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 2.96144904830488, "AMINOSALICYLIC": 3.1154892761955524, "AUBAGIO": 1.3429840709975502, "BRAFTOVI": 2.236318881032428, "BRILIQUE": 1.992272031198768, "BRINTELLIX": 1.1743143908918168, "BUDESONIDE": 1.1712134783416177, "BUSULFAN": 2.072825104284488, "CELLCEPT": 1.2672739663146102, "CHAMPIX": 1.187352434436928, "CICLOSPORIN": 2.7545128620951265, "CLOPIDOGREL": 3.859514856832439, "COSENTYX": 4.566369699487118, "ELIQUIS": 1.4782174651140838, "ENTYVIO": 17.850853444535716, "EXJADE": 1.1331385081472107, "HUMIRA": 5.571032566826793, "INFLIXIMAB": 4.994576768371735, "IPILIMUMAB": 2.286442173828978, "MERCAPTOPURINE": 9.609224261998609, "OFEV": 2.884805684208494, "PEGASYS": 1.4036324814870276, "PLAVIX": 1.710538862107666, "ROTATEQ": 29.65236647421152, "SAXENDA": 3.903181212810469, "SIMPONI": 3.983034612617074, "SOLIRIS": 1.7025857870650678, "SPRYCEL": 1.6797947674191045, "STELARA": 2.803135681677146, "SUTENT": 1.4695803963877636, "TAMIFLU": 3.9338235951842746, "TICAGRELOR": 10.417887976840806, "TWINRIX": 2.595402375200736, "VEDOLIZUMAB": 26.865440061831706, "VOTRIENT": 1.7218166145108704, "XARELTO": 2.3036907577629604, "XELJANZ": 2.7412488547525813, "YERVOY": 7.462390705172848, "null": 1.4788381758080438}
\ No newline at end of file
+{"COMBIVIR": 84.8471967157688, "null": 2.135158263087206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2452.json
index 13a1e579799..3cedaf6f268 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2452.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2452.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 32.928132622496214, "null": 1.3420443733646392}
\ No newline at end of file
+{"AIMOVIG": 3.178075505109658, "AVANDIA": 2.545929628653369, "CLOPIDOGREL": 1.859598299516388, "COMIRNATY": 1.3614115121254409, "ELIQUIS": 5.904078877327573, "EYLEA": 7.503559469208704, "JARDIANCE": 3.142500468601705, "PEGINTRON": 4.459796079300907, "SPIKEVAX": 0.6399976435069855, "VAXZEVRIA": 0.4027196551383669, "null": 0.65495896034846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2453.json
index bb76be8bdbf..3b7eb116671 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2453.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2453.json
@@ -1 +1 @@
-{"ALENDRONATE": 427.6668497195958, "APIXABAN": 38.52193672126027, "ARIPIPRAZOLE": 13.66317325269608, "AVANDIA": 10.627815105201469, "BRILIQUE": 5.564811636177595, "BUDESONIDE": 3.90560225138258, "CLOPIDOGREL": 2.8967512327550278, "DEXAMETHASONE": 2.592745173485102, "ELIQUIS": 2.8708311437213574, "ENTRESTO": 14.840339271146098, "FENTANYL": 3.887313282828965, "IBUPROFEN": 4.452926381456371, "JANUVIA": 3.791467854441077, "KYPROLIS": 16.898640232751088, "OPSUMIT": 2.066998286045499, "TASIGNA": 4.368524650715163, "ZOSTAVAX": 4.652107857374554}
\ No newline at end of file
+{"COMIRNATY": 1.0332086348123026, "null": 0.6795193461355182}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2454.json
index d998cea3b33..97898831462 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2454.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2454.json
@@ -1 +1 @@
-{"null": 1.7015648134381771}
\ No newline at end of file
+{"AZILECT": 196.65092767014187, "COMIRNATY": 1.8483574480023617, "SPIKEVAX": 1.3088579498039277, "TOZINAMERAN": 2.067766896232316, "VAXZEVRIA": 1.0424500315062597, "null": 0.209254361494827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2455.json
index eda44060f6f..58960465cc8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2455.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2455.json
@@ -1 +1 @@
-{"KEPPRA": 22.43941175487668, "null": 1.8501575574946736}
\ No newline at end of file
+{"COMIRNATY": 0.1976595815419238, "EMTRICITABINE": 23.98158578382504, "KALETRA": 8.909060317757262, "KEPPRA": 3.1602789768811066, "null": 2.523335858710252}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2456.json
index cd800fbce20..3491cb4bf8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2456.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2456.json
@@ -1 +1 @@
-{"KEPPRA": 173.16905913001102}
\ No newline at end of file
+{"VICTOZA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2457.json
index 000b3c166c2..36b178b7680 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2457.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2457.json
@@ -1 +1 @@
-{"LANTUS": 18.552145469382896}
\ No newline at end of file
+{"COMIRNATY": 0.3220597503386963, "ELIQUIS": 6.8461525890678345, "null": 1.4085975692858776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2458.json
index f0ea7593b16..03d47117228 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2458.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2458.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 12.592630827101331, "JARDIANCE": 5.387306326675446, "ROTATEQ": 82.95499891934783, "ZYPREXA": 5.387113282423931, "null": 1.342481169336058}
\ No newline at end of file
+{"COMIRNATY": 0.3568233542937782, "null": 0.6368191264323351}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2459.json
index 8f536f92681..b93a4e12b20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2459.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2459.json
@@ -1 +1 @@
-{"ELIQUIS": 10.919531897994723, "PLAVIX": 28.778328679139065, "null": 1.1186285327950696}
\ No newline at end of file
+{"KEPPRA": 148.2029576147614}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/246.json
index 945d0846375..513acc2c92d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/246.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/246.json
@@ -1 +1 @@
-{"ELIQUIS": 3.009285951837507, "EYLEA": 97.09030381125112, "FORSTEO": 6.422883223678346, "LANTUS": 3.054851123700373, "ZOSTAVAX": 5.63826087602621, "null": 1.4541551697738375}
\ No newline at end of file
+{"COMIRNATY": 0.1032523975955836, "HUMALOG": 3.1336223605258247, "IPILIMUMAB": 33.41518997901263, "KEYTRUDA": 6.863777668511075, "MEPOLIZUMAB": 44.98489942921089, "NUCALA": 54.47180909765106, "OPDIVO": 10.721286382533403, "VAXZEVRIA": 0.1412109498347212, "null": 0.5632129845352611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2460.json
index 346f3752634..e386672dc1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2460.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2460.json
@@ -1 +1 @@
-{"SPIKEVAX": 28.283889350267376}
\ No newline at end of file
+{"CLOPIDOGREL": 5.47298794574258, "COMIRNATY": 0.8015304019154124, "ELIQUIS": 20.334470805846276, "SPIKEVAX": 0.1564188225669381, "VAXZEVRIA": 0.4171283302479782, "null": 0.6442791945981218}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2461.json
index ae04dafdc43..cfb75bac316 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2461.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2461.json
@@ -1 +1 @@
-{"null": 1.9915552956419524}
\ No newline at end of file
+{"COMIRNATY": 0.770661735847557, "ELIQUIS": 3.0168285894050624, "SPIKEVAX": 0.6513516390650119, "TASIGNA": 11.71130004285754, "VAXZEVRIA": 0.5974990130845216, "null": 0.7500718880970881}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2462.json
index d43a30b6875..46254d628d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2462.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2462.json
@@ -1 +1 @@
-{"CYTARABINE": 38.50325125929505, "DEXAMETHASONE": 12.34487330368347, "TRISENOX": 6457.682812330478}
\ No newline at end of file
+{"COMIRNATY": 0.4338317165253183, "ICLUSIG": 60.35980947481789, "SPIKEVAX": 0.4675080670718318, "TASIGNA": 77.24234012237976, "null": 0.3838937207786571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2463.json
index f64f4f60da6..796abe1c6e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2463.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2463.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.2254168652998547, "ARANESP": 4.59568690268406, "AUBAGIO": 4.697011644250706, "BIKTARVY": 14.41012687130484, "COMIRNATY": 1.25807603587313, "CYMBALTA": 1.239341201254508, "ELIQUIS": 1.7365516503120273, "METHOTREXATE": 4.36622825250318, "XOLAIR": 2.6869496960160277}
\ No newline at end of file
+{"CELECOXIB": 40.87677108402424, "COMIRNATY": 0.6889641807641254, "ESOMEPRAZOLE": 139.12844813425593, "NOVOSEVEN": 76.9067716569572, "SPIKEVAX": 0.332643808913074, "VAXZEVRIA": 1.9230223538660047, "null": 0.5353166388092464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2464.json
index 232ac9849cf..48757bc6312 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2464.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2464.json
@@ -1 +1 @@
-{"ASPARAGINASE": 115.37471484915706, "BUSULFAN": 32.70588557987999, "CELLCEPT": 10.577247903228676, "CICLOSPORIN": 10.22910740326085, "FENTANYL": 6.016019842189261, "VEKLURY": 114.90542522580029}
\ No newline at end of file
+{"ALEMTUZUMAB": 85.21497400896588, "CASPOFUNGIN": 235.96961035641752, "IBRUTINIB": 287.7403297789392, "RITUXIMAB": 25.19115202430057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2465.json
index 5ed23e58722..f1e724f8d20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2465.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2465.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 15.042745800948628, "AXICABTAGENE": 56.71476246147901, "AZATHIOPRINE": 3.615964540311902, "BUSULFAN": 6.482789056245867, "CAELYX": 14.31536208390516, "CARMUSTINE": 31.67731317669775, "CELLCEPT": 17.543636239494596, "CICLOSPORIN": 10.941994272265118, "CLOPIDOGREL": 1.2825395938678046, "CYTARABINE": 33.22414470690555, "DEXAMETHASONE": 12.26780926600238, "DOXORUBICIN": 34.81941064044349, "EPCORITAMAB": 159.19376077073815, "JAKAVI": 10.12808825827324, "KYMRIAH": 281.69919468589995, "LENALIDOMIDE": 28.33090821670304, "METHOTREXATE": 4.2550864121936565, "MYCOPHENOLATE": 6.305544363025444, "OBINUTUZUMAB": 16.381827453046256, "OFATUMUMAB": 96.02542075337604, "POLATUZUMAB": 173.55008313044877, "RITUXIMAB": 33.001508828321526, "SIMPONI": 1.6422019372334868, "TACROLIMUS": 9.65208618744716, "TISAGENLECLEUCEL": 116.7143615763726, "YESCARTA": 88.44877055912738}
\ No newline at end of file
+{"null": 1.6305801185912183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2466.json
index b46b53c3bc1..7c7ff6d592e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2466.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2466.json
@@ -1 +1 @@
-{"CAELYX": 20.610196016135923, "CARMUSTINE": 205.6403978976627, "CYTARABINE": 109.84257728385565, "DEXAMETHASONE": 25.393054013737864, "DOXORUBICIN": 101.48669010949072, "KYMRIAH": 376.9993592030765, "MABTHERA": 49.93232641021019, "METHOTREXATE": 8.067824499709847, "OFATUMUMAB": 218.4133132089203, "RITUXIMAB": 65.52134446401145, "YESCARTA": 37.29693213465015}
\ No newline at end of file
+{"AZATHIOPRINE": 4.413451176760541, "CICLOSPORIN": 2.4248285430993524, "COMIRNATY": 0.1212720384533934, "JAKAVI": 2.946719614177709, "KEPPRA": 1.9285310265480688, "LEVETIRACETAM": 4.044566570875708, "MIDAZOLAM": 25.49824469367993, "OLANZAPINE": 3.889254285261574, "PLAVIX": 1.1910748011355838, "SPIKEVAX": 0.1953125998423757, "TOZINAMERAN": 0.2010430754636197, "ZOSTAVAX": 3.4911000268342414, "ZYPREXA": 2.798446420336941, "null": 2.075602578878088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2467.json
index b69f81fa6cd..ee640751074 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2467.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2467.json
@@ -1 +1 @@
-{"CAELYX": 103.41626631044566, "CANCIDAS": 163.16228952500327, "CARMUSTINE": 69.82304652318464, "CYTARABINE": 114.89787607503868, "DEXAMETHASONE": 26.700252151645184, "DOXORUBICIN": 94.08617766340936, "KYMRIAH": 125.3572413811146, "RITUXIMAB": 53.69899947678527}
\ No newline at end of file
+{"null": 1.9001059167326195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2468.json
index 43ee6f78f85..9cf2cbedaea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2468.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2468.json
@@ -1 +1 @@
-{"CICLOSPORIN": 23.100132546211896, "JAKAVI": 67.64561622615646, "RITUXIMAB": 49.54207641358289}
\ No newline at end of file
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2469.json
index bfd1ae8b520..2cc84dc5e19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2469.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2469.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2054199313401912}
\ No newline at end of file
+{"null": 1.288296456823669}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/247.json
index 720bff6cf0c..0664ff81cae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/247.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/247.json
@@ -1 +1 @@
-{"AERIUS": 1.656884058133744, "APROVEL": 2.181361147712342, "AVAMYS": 1.4310270187330352, "CABOMETYX": 2.0212394898688397, "CHAMPIX": 1.8191706564569137, "COMIRNATY": 1.4611015316092415, "COVID19": 1.9271866556283703, "ESBRIET": 1.7913207968310387, "FIRDAPSE": 1.634589094495586, "IBRANCE": 1.3941497726538543, "INLYTA": 1.0146623761027234, "LATUDA": 1.3927870182214923, "OFEV": 1.6795318284776075, "RELVAR": 2.823288073136704, "SPIKEVAX": 1.2000851136466613, "SUTENT": 7.004511393798643, "TOZINAMERAN": 2.041938635212197, "VAXZEVRIA": 1.2125435235172073, "VOTRIENT": 2.773918290459512, "XALKORI": 1.4281870748672738, "XTANDI": 1.9476693521641344, "ZELBORAF": 1.7395733987266109, "null": 1.201868048698083}
\ No newline at end of file
+{"BEVACIZUMAB": 9.852134001960035, "CAPECITABINE": 12.051493242314654, "CELLCEPT": 4.040274292800377, "CIMZIA": 1.853596132970947, "COMIRNATY": 0.061428602580528, "DOCETAXEL": 12.611528695925712, "JAKAVI": 6.824853500780653, "MYCOPHENOLATE": 14.050966833140434, "PEGASYS": 1.3078671130811614, "PEMBROLIZUMAB": 13.404970129232462, "PEMETREXED": 29.411759205478, "STELARA": 3.6225793491616263, "null": 0.7384810237993571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2470.json
index 1dd8cb9ff0f..b11e0d68ae1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2470.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2470.json
@@ -1 +1 @@
-{"CAPECITABINE": 182.57259841240776, "XELODA": 558.2720644150886, "null": 1.0019793231953782}
\ No newline at end of file
+{"ASPARAGINASE": 478.4146558212937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2471.json
index f0d9682d119..bbca2a7b713 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2471.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2471.json
@@ -1 +1 @@
-{"null": 6.78597621727484}
\ No newline at end of file
+{"GARDASIL": 46.8022731247579, "null": 0.5300222037649106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2472.json
index 4618109a75a..6b01af21c06 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2472.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2472.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 32.401935786044035, "ENTRESTO": 13.473400645138348, "null": 1.7583891867537071}
\ No newline at end of file
+{"null": 1.138120211151277}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2473.json
index 9a4dec102bb..6b514b87d07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2473.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2473.json
@@ -1 +1 @@
-{"null": 3.2233667657231773}
\ No newline at end of file
+{"null": 1.7594257260330517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2474.json
index df4287aa0f6..98ea5a29764 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2474.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2474.json
@@ -1 +1 @@
-{"AFINITOR": 1.0721317276531737, "APIXABAN": 4.500407327742218, "ASPARAGINASE": 5.250312001542403, "AVANDAMET": 21.715518874769412, "AVANDIA": 24.4372415832342, "AVASTIN": 1.9335507782027144, "BETAFERON": 6.03127253524514, "CAELYX": 6.819344488332185, "DEXAMETHASONE": 1.307313682180092, "DOCETAXEL": 2.76831511211151, "DOXORUBICIN": 5.365205940480204, "EFAVIRENZ": 9.576896828081043, "EMTRICITABINE": 8.613779352798565, "ENTRESTO": 14.265133013679788, "HERCEPTIN": 8.500444015601486, "IVABRADINE": 92.9027951113865, "LAMIVUDINE": 9.535679925356042, "PANTOPRAZOLE": 3.266267189842353, "PEGASYS": 1.238918023894754, "PEGINTRON": 1.0200369012663737, "RITUXIMAB": 1.6221962587868064, "SIMPONI": 1.046076063538521, "SOLIRIS": 1.364075322357003, "STELARA": 4.698417020725785, "SUTENT": 1.4531460440960913, "TAGRISSO": 3.147025142157053, "VALSARTAN": 17.279783813971164, "XOLAIR": 1.3006379368869951}
\ No newline at end of file
+{"AIMOVIG": 1.0892588893459392, "ARAVA": 0.4022989814965584, "ARIPIPRAZOLE": 1.6236526644561402, "AUBAGIO": 2.4275278959312487, "BENLYSTA": 1.965578426226056, "CHAMPIX": 0.8702656162006077, "CICLOSPORIN": 0.9313930817566866, "COMIRNATY": 0.23285254039988, "CYMBALTA": 1.3335898926913146, "ELIQUIS": 1.7534847277432548, "ENBREL": 0.945935816368342, "EXFORGE": 2.0859001851400167, "GARDASIL": 0.6449400881696573, "HUMALOG": 3.4571504921143634, "HYDROCORTISONE": 12.293685709605276, "IBRANCE": 2.451099046714246, "IBUPROFEN": 1.6256441510729798, "INSULIN": 1.706296401088926, "IRESSA": 3.181319889664957, "KEPPRA": 2.0337845951180418, "KEYTRUDA": 0.8826674286851243, "LANTUS": 1.8706491824225429, "LEVETIRACETAM": 2.050262731303567, "LYRICA": 2.760526081839542, "MEKINIST": 2.38041950983578, "OLANZAPINE": 0.8155909880562263, "PEGASYS": 0.4763540861514436, "PLAVIX": 0.6314714080663685, "RITUXIMAB": 3.161880019241564, "SPIKEVAX": 0.1834015505555044, "SUBOXONE": 3.3884476170113964, "SUTENT": 0.7106087783143742, "TOVIAZ": 3.632783778645541, "TOZINAMERAN": 0.7449520290665034, "VAXZEVRIA": 0.0972518537884545, "VIAGRA": 1.5889790751416917, "XELJANZ": 1.1696427309941542, "XTANDI": 1.2318879903808846, "ZYPREXA": 1.2716933701779871, "null": 1.6124841002535493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2475.json
index fa018f6a390..c12d274b236 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2475.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2475.json
@@ -1 +1 @@
-{"null": 1.3805811357358588}
\ No newline at end of file
+{"null": 1.308269228709178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2476.json
index a903706aba5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2476.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2476.json
@@ -1 +1 @@
-{"ATAZANAVIR": 7.374381317448041, "COMIRNATY": 1.000787707669805, "ENOXAPARIN": 6.882584813459095, "FENTANYL": 3.265968730831285, "FORSTEO": 2.16844663818829, "GARDASIL": 7.928637210571082, "SHINGRIX": 2.131450858535953, "TOZINAMERAN": 1.0430288770378189, "VAXZEVRIA": 1.6261700200420186, "XTANDI": 1.7553876703679228, "ZOSTAVAX": 1.6771099706599195}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2477.json
index ff50adc54c3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2477.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2477.json
@@ -1 +1 @@
-{"ABACAVIR": 5.919992515891461, "ABILIFY": 1.1475087694448889, "ALEMTUZUMAB": 2.3841301015843754, "APIXABAN": 14.309936315100297, "ATAZANAVIR": 5.372917610885135, "AUBAGIO": 2.2924493911566435, "AZILECT": 4.4984197913379145, "BETAFERON": 1.9599947742206745, "BRIVIACT": 4.293936965457269, "BUPIVACAINE": 4.695482313140665, "CHAMPIX": 1.0724050269404148, "CRIXIVAN": 8.567519225773303, "ENFUVIRTIDE": 28.971876298800037, "EVISTA": 1.0349059432298748, "EXFORGE": 1.518787026199993, "EYLEA": 1.3525206586839431, "FAMPYRA": 1.0961121709470294, "FIRDAPSE": 6.9382630421549285, "FYCOMPA": 5.439592715976101, "GARDASIL": 2.1760861979223804, "KEPPRA": 3.1220804640182958, "KESIMPTA": 1.9677009128754703, "KEYTRUDA": 1.158795307691642, "LACOSAMIDE": 13.4681378783447, "LEMTRADA": 2.3831548823992024, "LEVETIRACETAM": 1.1464987271890283, "LYRICA": 3.0519599311044723, "MAVENCLAD": 2.2777941921831943, "NIMENRIX": 1.2598235311976809, "OPDIVO": 1.3608345521610683, "PREGABALIN": 1.220345554054662, "SAQUINAVIR": 79.86579112512173, "SIFROL": 4.799839783460544, "SILDENAFIL": 1.1384083640904172, "TAMIFLU": 1.413516354289993, "TOVIAZ": 1.495075404600768, "TOZINAMERAN": 1.1898944839325505, "TWINRIX": 2.0188113571126785, "VFEND": 4.40832791286407, "VIAGRA": 2.652691510145827, "VIMPAT": 14.679877043416138, "VORICONAZOLE": 1.324956266075758, "XALKORI": 1.293384647039901, "XTANDI": 1.1403238912060802, "ZOSTAVAX": 1.647346312769571, "null": 1.1111444367412349}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2478.json
index 4bafb15500e..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2478.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2478.json
@@ -1 +1 @@
-{"ABATACEPT": 11.797666383255653, "ABILIFY": 2.2401280234567853, "ADALIMUMAB": 11.01487995314442, "ALEMTUZUMAB": 2.2511499766809986, "APIDRA": 4.110727697261855, "APREMILAST": 3.594502714886528, "ARAVA": 1.992335484104215, "AUBAGIO": 1.8494447547880155, "AVANDIA": 2.575245743437605, "BENLYSTA": 2.911525200322367, "COSENTYX": 1.993357138270065, "ENBREL": 2.649641844161177, "ENTYVIO": 1.4653024471765226, "GARDASIL": 1.065546007474289, "HUMIRA": 3.281130647581377, "INSULIN": 1.2269029886621088, "KEPPRA": 2.72735157256043, "LANTUS": 14.96175035963657, "LEMTRADA": 1.3377199737291097, "LEVEMIR": 9.672015123887183, "LYRICA": 1.5957411275718525, "OZEMPIC": 8.755747922266115, "SAXENDA": 3.019790070550251, "STELARA": 2.4069482860646376, "SUBOXONE": 4.5035243525296735, "TOUJEO": 14.68356855096157, "TRELEGY": 3.371868173159086, "TREMFYA": 3.3556239053043524, "TRESIBA": 4.77506479281863, "TWINRIX": 4.081461293896608, "VICTOZA": 5.528267150056457, "ZYPREXA": 1.0731743339413071, "null": 1.345443066613892}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2479.json
index da874a56d80..e3d99742072 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2479.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2479.json
@@ -1 +1 @@
-{"JANUVIA": 47.95484363882093, "METHOTREXATE": 149.32577481034104}
\ No newline at end of file
+{"BRILIQUE": 28.671704250141968, "CLOPIDOGREL": 15.959296920697764, "COMIRNATY": 0.1333763629956478, "EFIENT": 17.185782528429502, "ELIQUIS": 27.013177276422677, "ENOXAPARIN": 4.799247515370972, "ENTRESTO": 1.7486777803292026, "METALYSE": 393.1247726909989, "NEXAVAR": 0.872502166921167, "PEGASYS": 0.4273192304373355, "PLAVIX": 26.290111189774876, "PRADAXA": 11.21386438796598, "RASBURICASE": 73.30766422279504, "SPIKEVAX": 0.0437832525460311, "SUTENT": 0.4528562140750817, "VAXZEVRIA": 0.1735157849206855, "XARELTO": 13.490481591423986, "ZYPREXA": 0.6923119471593193, "null": 1.447748200562022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/248.json
index 0ba66ce5ec4..141aa88a42e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/248.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/248.json
@@ -1 +1 @@
-{"ABILIFY": 7.282472135830056, "AERIUS": 8.842251938517835, "ANTIBIOTICS": 4.091737896443417, "ARIPIPRAZOLE": 4.105577467185708, "AXURA": 11.30751142083474, "BIKTARVY": 1.1074866639254344, "BLINDED": 14.535234038188143, "BOCEPREVIR": 2.9183720884033093, "BRINTELLIX": 6.06833918123479, "BRIVARACETAM": 13.718824718970282, "BRIVIACT": 21.39616270142542, "BUMETANIDE": 4.057387510271644, "BUPRENORPHINE": 2.165610211180338, "CANNABIDIOL": 4.859331363345334, "CARBIDOPA": 1.7444349828172991, "CARFILZOMIB": 1.4738182011778864, "CARIPRAZINE": 10.926777059125843, "CELSENTRI": 3.2454797414966223, "CHAMPIX": 20.10842703355831, "CIRCADIN": 5.947004397993815, "COMTAN": 3.213791618459928, "CYMBALTA": 3.440110293971754, "DELAMANID": 1.3772291808432593, "DESLORATADINE": 2.2133642558313658, "DULOXETINE": 1.8977168595648224, "EBIXA": 11.19836694141282, "EPIDYOLEX": 15.259360716774268, "EXELON": 8.75118043909636, "FENTANYL": 1.206230375674592, "FYCOMPA": 54.633926663663935, "IBUPROFEN": 1.2361139568317807, "INTRONA": 4.181127741410827, "INVEGA": 7.991755507224294, "KAFTRIO": 3.910124136844948, "KEPPRA": 14.279978471850908, "KUVAN": 4.067437477392114, "LACOSAMIDE": 5.456948478188613, "LATUDA": 6.252346600649236, "LEVETIRACETAM": 12.187562621272214, "LEVODOPA": 2.058743224429961, "LURASIDONE": 13.398758145226614, "LYRICA": 2.502536961681152, "MELATONIN": 4.994595058462952, "MEMANTINE": 15.149752151390114, "MIDAZOLAM": 2.5617096540558792, "OLANZAPINE": 6.04988281386844, "OLYSIO": 1.472116294728236, "OXYBUTYNIN": 1.6353939497558545, "PANTOPRAZOLE": 1.1950878257134163, "PEGASYS": 1.6806503266766637, "PEGINTERFERON": 1.3203564572556528, "PEGINTRON": 3.2070435027517714, "PERAMPANEL": 33.183438752010844, "PREGABALIN": 4.57899622752631, "REAGILA": 5.598032410133944, "REBETOL": 1.9972835741510917, "RISPERIDONE": 4.053013405625042, "SIFROL": 5.269033713701167, "SLENYTO": 75.87874501894635, "STALEVO": 4.866415552809968, "SUBOXONE": 1.1652793374254808, "SYCREST": 1.9386642975192327, "TAMIFLU": 3.032944017602504, "TESTOSTERONE": 4.5183831739044376, "TIVICAY": 1.6266201646975995, "VARENICLINE": 4.815008733020612, "VIMPAT": 7.013525434769154, "WAKIX": 8.930435894476338, "ZYPADHERA": 7.693713985210725, "ZYPREXA": 4.120879718859056, "null": 2.6931713507479467}
\ No newline at end of file
+{"null": 0.7124853910337042}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2480.json
index 1c4fb3db80e..0dd1a85759e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2480.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2480.json
@@ -1 +1 @@
-{"TOZINAMERAN": 1.390469354011936}
\ No newline at end of file
+{"ABACAVIR": 0.0960975731073851, "ADENURIC": 2.6190569321645776, "ADVATE": 3.8508492116380815, "AFINITOR": 0.4181987639526053, "AIMOVIG": 0.3975917789782432, "ANGIOX": 6.251988302359264, "APIXABAN": 0.6824505444944948, "APROVEL": 0.7453433180782145, "ARANESP": 0.2813604244986924, "ARAVA": 0.0189142787578736, "ARIXTRA": 11.069180822578817, "ASPARAGINASE": 2.0193093812864915, "AUBAGIO": 0.4005673298209887, "AVANDIA": 0.4615140734854517, "AVASTIN": 2.281554901741985, "AZACITIDINE": 0.8733354156672043, "BENLYSTA": 0.1838816790252747, "BETAFERON": 0.9395387670913904, "BEVACIZUMAB": 0.3762648560304648, "BRAFTOVI": 0.7269259172145368, "BRILIQUE": 16.268464590339512, "BRINTELLIX": 0.314832466458359, "BUDESONIDE": 0.1241833546836628, "BUSULFAN": 0.9149229239199728, "BYDUREON": 0.1636402870215577, "CABOMETYX": 0.5160330608364452, "CANCIDAS": 0.9669905749034996, "CASPOFUNGIN": 1.276613298520639, "CELLCEPT": 0.4281834064463217, "CHAMPIX": 0.2176273507518561, "CICLOSPORIN": 0.6072061064172759, "CIMZIA": 0.078500153218668, "CLOPIDOGREL": 8.629095042121566, "COMIRNATY": 0.3234615092337424, "COTELLIC": 1.4729348466546293, "CYMBALTA": 0.197097516641957, "CYTARABINE": 0.7458067750413092, "DEFITELIO": 8.521165245272234, "DEXAMETHASONE": 0.4051684167335372, "DUOPLAVIN": 12.375280399412684, "EBIXA": 1.9635638740238488, "EFIENT": 26.87872470910498, "ELIQUIS": 24.7716060058438, "ENOXAPARIN": 4.567303939783487, "ENTACAPONE": 1.8437982685668184, "ENTRESTO": 0.3146374246843197, "ERLEADA": 0.8775314401293521, "ESBRIET": 0.2762986620478129, "EVENITY": 6.3443704720361405, "EXFORGE": 0.3101103628672314, "EXJADE": 0.8564023350268636, "EXVIERA": 1.019380371255154, "EYLEA": 1.814068446662388, "FASENRA": 0.2681201157152229, "FORSTEO": 0.437768684292917, "FORXIGA": 0.1842038481276821, "HARVONI": 1.78629452278988, "HEMLIBRA": 3.915056627534883, "HUMALOG": 0.3257975813344902, "HUMAN": 0.5689702443712463, "IBRANCE": 0.2122809480200652, "IBUPROFEN": 0.2343997640804258, "ICLUSIG": 1.1833397153326697, "INLYTA": 1.3918148673340718, "INTEGRILIN": 13.394588598119425, "INTRONA": 4.178954828261928, "INVEGA": 1.940412847154828, "IRESSA": 0.6623005616142967, "ISCOVER": 8.576455355686022, "JAKAVI": 1.5051130129275094, "JANUMET": 0.2027655681519553, "JANUVIA": 0.2552349338136029, "JARDIANCE": 0.2878974041083967, "JEVTANA": 1.4215255566165346, "KALETRA": 0.4588883011127251, "KEPPRA": 0.6728586038610683, "KEYTRUDA": 0.7337231165321919, "LANTUS": 0.2561387952210329, "LEMTRADA": 0.40204061732135, "LENVIMA": 5.19294244221353, "LEVEMIR": 0.224217189288952, "LEVETIRACETAM": 0.4634395767685159, "LEVOFLOXACIN": 0.1417856701405858, "LIXIANA": 18.79735478375084, "LYRICA": 0.4000764894463169, "MABTHERA": 0.8832430242018592, "MEKINIST": 1.7918202834657413, "METALYSE": 179.7815841222343, "METHOTREXATE": 0.3215823676750461, "MICARDIS": 1.491712978691229, "MIDAZOLAM": 2.120408355578471, "MIRCERA": 2.6203625704273983, "NEXAVAR": 3.202158516878405, "NORVIR": 0.6792120218177087, "NOT": 0.49115568029904, "NOVOSEVEN": 4.722719853344857, "NPLATE": 1.666314702210883, "OFEV": 0.3670427637730187, "OLANZAPINE": 0.0864173299842516, "ONCASPAR": 1.9260166100979408, "OPDIVO": 0.5202666694404805, "OPSUMIT": 0.4438669429518028, "PEGASYS": 1.618963900369902, "PEGINTERFERON": 0.2202073481192769, "PEGINTRON": 2.540970976298055, "PLAVIX": 22.111684213579125, "PRADAXA": 6.267278424431333, "PRASUGREL": 12.274174471349715, "PRAXBIND": 26.30702910336432, "RAPILYSIN": 325.604758280221, "RASILEZ": 0.6064338223203194, "REBETOL": 1.702126312763056, "RETEPLASE": 37.31248016267699, "REVATIO": 0.8599620200966951, "RINVOQ": 0.6619706187851109, "RIVAROXABAN": 2.8593007264503445, "ROACTEMRA": 0.4761774266274502, "SILDENAFIL": 1.954467919896915, "SIMPONI": 0.4181221306515497, "SOLIRIS": 1.0091693409854785, "SOVALDI": 2.4261612946622457, "SPIKEVAX": 0.2122468755389416, "SPIRONOLACTONE": 0.7557641543555236, "SPRYCEL": 1.2317852057314225, "STALEVO": 0.7821084530210207, "STELARA": 0.2582251390251046, "STIVARGA": 1.2616795997473933, "SUTENT": 1.7749825649835504, "TAGRISSO": 0.4634366041812423, "TASIGNA": 0.9669486676701292, "TEMODAL": 3.0396994652250915, "TICAGRELOR": 7.171756197195853, "TORISEL": 2.760483759069148, "TOZINAMERAN": 0.2387206969406631, "TRACLEER": 0.7306330614344346, "TREMFYA": 0.377275170860415, "TRULICITY": 0.2126613070779758, "VAXZEVRIA": 0.3246425848819971, "VFEND": 0.2324947237399023, "VIAGRA": 1.7375334178713548, "VICTOZA": 0.3915564500287875, "VIMPAT": 0.5055973923159108, "VORICONAZOLE": 0.5125528029548831, "VOTRIENT": 1.7058954177071235, "XALKORI": 0.4418999262312797, "XARELTO": 10.43877444302644, "XELJANZ": 0.2139488179977324, "XOFIGO": 1.2668349499095166, "XOLAIR": 0.1486836359581944, "XTANDI": 0.7099739393101683, "YERVOY": 1.4139183446337331, "YESCARTA": 0.4954243416790124, "ZOSTAVAX": 0.1747868911510793, "ZYPREXA": 0.2207650732823805, "null": 1.278916482021954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2481.json
index 7f1d04556e2..1919a56c1e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2481.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2481.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 11.3568209162791, "OLANZAPINE": 30.92079707612087, "PLAVIX": 6.5218593584853695, "SUTENT": 1.7933735484022637}
\ No newline at end of file
+{"MIDAZOLAM": 226.17298230955137, "null": 1.9394105009784244}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2482.json
index 8066a70d659..10e9a939df6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2482.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2482.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.2778022687549382, "ABATACEPT": 5.391043992362601, "ACETAMINOPHEN": 17.43727164043431, "ADALIMUMAB": 12.412892264846462, "AIMOVIG": 2.3319618163685942, "APREMILAST": 9.890262784334508, "APREPITANT": 22.677592482980696, "ARAVA": 12.537173983712538, "BOTULINUM": 1.3146508846787537, "BUPIVACAINE": 2.2305058301037506, "CABOTEGRAVIR": 2.8708342729653125, "CIMZIA": 1.769013321868656, "COSENTYX": 2.145706096494832, "EMPAGLIFLOZIN": 1.2616276076444737, "ERELZI": 3.4515813647105054, "FIRDAPSE": 1.1646285886105514, "FORSTEO": 1.3459852628056206, "FULVESTRANT": 1.2150551006418748, "GLYCOPYRRONIUM": 13.775107205082568, "HUMIRA": 1.5787854996504878, "HYDROCORTISONE": 1.1753436614856976, "IRBESARTAN": 1.8503225024640155, "MEPOLIZUMAB": 1.4070587663987144, "MYCOPHENOLATE": 1.2767393805850935, "OMALIZUMAB": 1.4802343936118671, "OPTIMARK": 1.1100391636261564, "PANTOPRAZOLE": 1.5540809804191456, "RAPISCAN": 19.64906753404985, "REKAMBYS": 4.082689725855926, "RELVAR": 1.2687354252558125, "RITUXIMAB": 1.3271160074713262, "RYBELSUS": 1.047133460758103, "SAXENDA": 1.8319418235041125, "SHINGRIX": 1.932985850896736, "TOPOTECAN": 1.5199108434843662, "TOUJEO": 1.0003633834347954, "TOZINAMERAN": 1.3702061559276966, "TRULICITY": 1.0383436297913444, "VALSARTAN": 1.6774227113288551}
\ No newline at end of file
+{"null": 2.5894735997659377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2483.json
index 772ad1c670e..70f0dbf4b1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2483.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2483.json
@@ -1 +1 @@
-{"BENLYSTA": 20.354368244169887, "NUCALA": 6.936627179755137, "XELJANZ": 28.66820406371703, "null": 1.91215010436841}
\ No newline at end of file
+{"AZILECT": 238.31788633870607, "CARBIDOPA": 323.18982521523907, "null": 1.9481413764587336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2484.json
index 5b6926dd631..3ce10aa6eaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2484.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2484.json
@@ -1 +1 @@
-{"CYTARABINE": 6.312276635523843, "HUMIRA": 4.249903297783173, "IBUPROFEN": 4.432109074221251, "ICLUSIG": 52.22913201027892, "JANUMET": 8.313340450689847, "JANUVIA": 4.790645945058527, "JARDIANCE": 4.560793083191063, "LANTUS": 3.3337199542159484, "OPSUMIT": 18.527501521369302, "SOLIRIS": 6.438250251137331, "SUTENT": 1.2791792051970088, "TRACLEER": 24.96451421504545, "TRELEGY": 12.64212047139312, "null": 1.0614192755901524}
\ No newline at end of file
+{"ACTOS": 1.9736151845009997, "AFINITOR": 0.282086229391544, "ALIMTA": 2.3467513619486966, "AMINOSALICYLIC": 0.5411343842466092, "APIXABAN": 0.3886866571070027, "ARANESP": 0.4753129226436415, "ASPARAGINASE": 1.4852865006154576, "AVANDAMET": 2.357329880691526, "AVANDIA": 2.830299260737553, "AVASTIN": 3.974559677655221, "BEVACIZUMAB": 0.6355684019541525, "BIKTARVY": 0.7975500307528304, "BYETTA": 0.262099388536065, "CABOMETYX": 1.0645621208003897, "CANNABIDIOL": 5.447597248538198, "CELLCEPT": 1.081317247116132, "CHAMPIX": 0.9274809276898734, "CICLOSPORIN": 0.6760832785870556, "CIMZIA": 0.1814121992141853, "CLOPIDOGREL": 3.179937006234771, "COAPROVEL": 1.3300552994918236, "COMIRNATY": 1.027780194730574, "COMTAN": 1.4928790720441532, "COSENTYX": 0.3131117421440023, "CYMBALTA": 0.365629856146463, "CYTARABINE": 0.2951858802020764, "DARZALEX": 0.7127477972428862, "DEXAMETHASONE": 0.7407939466090969, "DOCETAXEL": 0.3954773385769873, "EFIENT": 10.28740006696944, "ELIQUIS": 13.793053785381304, "ENOXAPARIN": 0.956554994458776, "ENTRESTO": 0.2623640609146185, "ENTYVIO": 0.2985427822072341, "ENZALUTAMIDE": 1.989157006724133, "ERLEADA": 1.170042930850154, "EVENITY": 37.763819754613, "EVISTA": 7.769550889179011, "EXFORGE": 1.0058652379964557, "EXJADE": 0.2553528584300258, "EYLEA": 20.01484590455702, "FASLODEX": 0.6418114255047361, "FENTANYL": 0.46601347957556, "FESOTERODINE": 51.30963731475755, "FORSTEO": 0.3572606787703146, "FORXIGA": 5.475349693460229, "HARVONI": 0.9786188417900644, "HEMLIBRA": 4.473312702598258, "HERCEPTIN": 0.8444857585234901, "HUMALOG": 1.659897080357936, "HUMAN": 1.1514941211451255, "IBRANCE": 0.1536962842583283, "IBUPROFEN": 0.2568595068824781, "ICLUSIG": 10.697099509547677, "INFLIXIMAB": 1.3955825976849394, "INLYTA": 2.7667693661497403, "INSULIN": 0.6469957467671518, "INTRONA": 2.615170887647368, "IRESSA": 4.390647290760168, "ISENTRESS": 1.2300449798012782, "JAKAVI": 1.0432789206597133, "JANUMET": 0.3762303968254868, "JANUVIA": 1.443849685835669, "JARDIANCE": 2.2571526020907817, "JEVTANA": 1.065417971846347, "KALETRA": 0.7751959950435359, "KEPPRA": 0.3940807207388501, "KEYTRUDA": 2.015942754939496, "LANTUS": 0.6400935475243998, "LENVIMA": 6.638697528789071, "LEVEMIR": 0.3786959459980615, "LEVETIRACETAM": 0.3997049148698244, "LEVOFLOXACIN": 0.2630822877970528, "LIXIANA": 6.839039001373485, "LYRICA": 0.2508533273242239, "MEKINIST": 0.6125267897402359, "METFORMIN": 3.3476222809366543, "METHOTREXATE": 0.3212891273483063, "MICARDIS": 2.0751201419125627, "MIRCERA": 1.702517169280925, "MYCOPHENOLATE": 0.826906251951068, "NEXAVAR": 3.449978452833957, "NILOTINIB": 3.666792595541985, "NOT": 1.5119475631449406, "NOVORAPID": 0.5516722393102589, "NOVOSEVEN": 24.097896312405474, "NPLATE": 0.7146454669696288, "OFEV": 1.9296996083028397, "OLANZAPINE": 0.7745527945453823, "ONCASPAR": 3.2536025978735297, "OPDIVO": 1.3743338222991035, "PEGASYS": 0.851022683079074, "PEGINTRON": 2.8655319410860622, "PEMBROLIZUMAB": 0.5918506508941368, "PLAVIX": 3.148334728900812, "PRADAXA": 2.0183107372755544, "PRAXBIND": 9.949272502517452, "RASILEZ": 1.2975056892440555, "REBETOL": 1.727059219782045, "REMICADE": 1.1274991678100026, "RINVOQ": 0.9517981202551956, "ROACTEMRA": 1.1364934526345989, "SAMSCA": 24.206126142812487, "SHINGRIX": 0.2108038744216648, "SILDENAFIL": 1.2545480654530807, "SIMPONI": 0.4155687230285809, "SOLIRIS": 0.5094737684619283, "SOMATROPIN": 3.2111979663106425, "SOVALDI": 3.809744463535769, "SPIKEVAX": 0.3642824817999285, "STELARA": 0.8218003681958117, "STIVARGA": 1.8543475575297044, "SUTENT": 0.6340807140482286, "TAGRISSO": 3.4034875300558856, "TAMIFLU": 0.4463193305199112, "TASIGNA": 8.41923389093852, "TEMODAL": 1.6664619983496258, "TOZINAMERAN": 0.1657383319709047, "TRULICITY": 0.4451436463773108, "VAXZEVRIA": 0.3974317576332198, "VECTIBIX": 2.0934559341406835, "VEMLIDY": 7.658873699605869, "VFEND": 0.5649902361656376, "VIAGRA": 2.6578668777137664, "VICTOZA": 0.7213927059508682, "VIMPAT": 0.9381374957988742, "VOTRIENT": 0.5134597001441313, "XALKORI": 0.9454670402860008, "XARELTO": 2.1204028019335257, "XELJANZ": 0.2222538093999827, "XOLAIR": 0.2096206910594251, "XTANDI": 1.7403751205035147, "ZOSTAVAX": 0.5316357439595436, "ZYPREXA": 0.9206592963683052, "null": 0.8445403591649643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2485.json
index deac503279e..4d1e90ad6d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2485.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2485.json
@@ -1 +1 @@
-{"SHINGRIX": 165.76668080753683}
\ No newline at end of file
+{"APIXABAN": 1.209697249766303, "ASPARAGINASE": 7.932030498237815, "AVANDIA": 1.583329609145549, "AVASTIN": 3.7653134912833535, "CELLCEPT": 2.915421259496537, "CICLOSPORIN": 1.3966215771061865, "CLOPIDOGREL": 1.1564931862050498, "COMIRNATY": 0.8208311634239996, "ELIQUIS": 3.2092872323702504, "ICLUSIG": 11.802743506450035, "INSULIN": 2.0043209818923096, "LANTUS": 0.5277352681610529, "LIXIANA": 9.805514585996791, "METHOTREXATE": 1.2542808540432715, "NOVOSEVEN": 49.06690376038344, "NUCALA": 1.6623128382428058, "OLANZAPINE": 2.026329229466, "PLAVIX": 1.041938128452905, "SOLIRIS": 2.447746903307313, "SPIKEVAX": 0.4204791509203599, "SUTENT": 1.0431814665021948, "TOZINAMERAN": 0.2286780759490944, "VAXZEVRIA": 0.4235397411006696, "ZYPREXA": 1.037073219266379, "null": 1.192700852458573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2486.json
index 9b8650917d1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2486.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2486.json
@@ -1 +1 @@
-{"ABECMA": 102.944575958747, "ABEMACICLIB": 3.1412143460413438, "ABIRATERONE": 19.19293996840077, "ABRAXANE": 5.21830205447912, "ACALABRUTINIB": 55.143023382756525, "ADCETRIS": 3.0142230171170707, "AFATINIB": 23.84815653129202, "AFINITOR": 2.9406368613263028, "AFLIBERCEPT": 5.819043052466748, "ALECTINIB": 15.656924415897135, "ALIMTA": 2.222518193787234, "ALPELISIB": 3.180679690230368, "AMBRISENTAN": 1.3937743530031543, "AMIKACIN": 1.1534394257476366, "ARIPIPRAZOLE": 1.0682699456448477, "ARZERRA": 4.333681094365547, "ATEZOLIZUMAB": 15.056807582566115, "AVAPRITINIB": 15.402339030639132, "AVASTIN": 28.22371270782651, "AVELUMAB": 24.667426889164616, "AXICABTAGENE": 15.504676526452686, "AXITINIB": 7.010664653476092, "AZACITIDINE": 4.20052370793295, "AZATHIOPRINE": 1.8382485273632383, "BAVENCIO": 14.28773988521418, "BELANTAMAB": 21.492601542753423, "BEVACIZUMAB": 17.303590059802296, "BINIMETINIB": 3.22284175241883, "BINOCRIT": 2.6595364504418875, "BLINATUMOMAB": 7.475384834168018, 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\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2487.json
index 4db7490ba70..5a0d6da2063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2487.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2487.json
@@ -1 +1 @@
-{"ABILIFY": 2.3366401785817024, "ACLASTA": 10.52068280893208, "ALEMTUZUMAB": 1.6446944249542432, "AMIKACIN": 6.960585413412245, "ARIPIPRAZOLE": 1.8047673079587496, "ASPARAGINASE": 1.3499787776302286, "AVAMYS": 2.1374249897447597, "AZACITIDINE": 3.2231194505925878, "AZATHIOPRINE": 4.998667833221429, "BASILIXIMAB": 9.549150639687678, "BENLYSTA": 2.3263480171405644, "BEVACIZUMAB": 2.9980416068610043, "BORTEZOMIB": 2.891754458033989, "BRINTELLIX": 1.2149370465636973, "BUDESONIDE": 1.3672872553307114, "BUSILVEX": 14.74881943694129, "BUSULFAN": 2.807656527548968, "CAPECITABINE": 2.9929378388307533, "CARMUSTINE": 8.6425599556636, "CELECOXIB": 1.574682091386975, "CHAMPIX": 2.178351501359972, "CICLOSPORIN": 5.8191837501328845, "CLADRIBINE": 6.596649099617163, "CLINDAMYCIN": 25.15581425248938, "COMIRNATY": 1.3525135045883432, "COSENTYX": 1.6821828134060042, "CYTARABINE": 5.520821180831333, "DABRAFENIB": 2.3186438956629987, "DEXAMETHASONE": 2.5756799258711207, "DIFICLIR": 21.825328638329424, "DOCETAXEL": 2.617103535320575, "DOXORUBICIN": 2.5475233043321355, "EFAVIRENZ": 1.4651726309591384, "ESOMEPRAZOLE": 2.617283852208753, "FASLODEX": 1.239362353897267, "FIDAXOMICIN": 21.4153122058721, "HEPSERA": 2.2589199340022503, "HERCEPTIN": 1.359706064395278, "HYDROCORTISONE": 4.369353163680615, "IMATINIB": 4.067362611445565, "INFLIXIMAB": 2.0283104752341763, "IRINOTECAN": 1.5808823103287315, "KESIMPTA": 4.121766049866988, "KYMRIAH": 4.768185422539154, "LACOSAMIDE": 4.323052699964014, "LEMTRADA": 1.5318692180544309, "LEVETIRACETAM": 2.780853434363451, "LYNPARZA": 2.156441568350458, "MABTHERA": 2.5983683547370484, "MERCAPTOPURINE": 5.336959603490218, "METHOTREXATE": 2.145774538073849, "MYCOPHENOLATE": 1.7848412343067326, "NUCALA": 2.864808161385091, "OLANZAPINE": 1.6035915256480553, "PANTOPRAZOLE": 5.858746857061088, "PEGASYS": 1.0463756452476125, "PEGINTERFERON": 2.278641552618645, "RITUXIMAB": 2.619232298635682, "RUXOLITINIB": 4.717073933498607, "SOLIRIS": 4.0509259955231744, "SOMATROPIN": 10.460935280923849, "SYCREST": 4.334377342903216, "TEMOZOLOMIDE": 13.053283133201347, "TOPOTECAN": 10.205481727110444, "TOZINAMERAN": 6.732052218943255, "VFEND": 3.626196944954191, "VORICONAZOLE": 1.8685986688309528, "XELJANZ": 4.982286237610257, "YESCARTA": 5.695378780197661}
\ No newline at end of file
+{"BRILIQUE": 22.442692398907173, "CLOPIDOGREL": 12.709476111082104, "ELIQUIS": 10.674431628755128, "PLAVIX": 5.777309687685687, "VAXZEVRIA": 0.5702164834749387, "null": 0.8572326732449281}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2488.json
index 5f19c80fb29..12297cca59e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2488.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2488.json
@@ -1 +1 @@
-{"ARAVA": 4.002971819270885, "COMIRNATY": 1.864844800487777}
\ No newline at end of file
+{"COMIRNATY": 0.5472880037410679, "null": 0.426755866955994}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2489.json
index 3129f1f601c..b688addbb21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2489.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2489.json
@@ -1 +1 @@
-{"ABILIFY": 138.02771173803418, "ARIPIPRAZOLE": 245.11395618419272, "CANNABIDIOL": 46.48321769964711, "CHAMPIX": 2.3321110003189918, "CYMBALTA": 2.0494700878486056, "KEPPRA": 2.1520247969277677, "OLANZAPINE": 5.750037767893161, "ZYPREXA": 2.931223054429402}
\ No newline at end of file
+{"CLOPIDOGREL": 12.581219841159944, "COMIRNATY": 0.2486924415438756, "ELIQUIS": 7.735251737331661, "null": 0.8345190765777832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/249.json
index 02989fcb9a6..6506d4e6d0f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/249.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/249.json
@@ -1 +1 @@
-{"CHAMPIX": 28.458013389646744, "OLANZAPINE": 36.11741074022127, "null": 1.0377668077532147}
\ No newline at end of file
+{"BEVACIZUMAB": 30.152565133733404, "COSENTYX": 2.968428628449614, "ENTYVIO": 13.484644593233384, "IRINOTECAN": 17.625797895936913, "RINVOQ": 8.502584586204156, "ROACTEMRA": 13.213144566182264, "SIMPONI": 4.224459404729405, "STELARA": 11.529833610117878, "STIVARGA": 37.6148695725063, "null": 0.5859546345216068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2490.json
index 85d7620afcb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2490.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2490.json
@@ -1 +1 @@
-{"ABATACEPT": 56.30628458589917, "ADALIMUMAB": 66.0487093083409, "AMINOSALICYLIC": 9.009683414896852, "APREMILAST": 221.507324583466, "ARAVA": 2.1452598055171865, "COSENTYX": 3.811897343632617, "ENTYVIO": 2.890839680098303, "RITUXIMAB": 3.152980222828206}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2491.json
index 154aa9d4ea9..e21dcc82ab4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2491.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2491.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 6.310039876585936, "INSULIN": 3.6206086184757336, "KEPPRA": 1.4108408654753213, "LEVOFLOXACIN": 8.736299620696448, "OLANZAPINE": 2.486484061739235, "VFEND": 73.83885576482369, "VORICONAZOLE": 64.52847963130108, "null": 2.003948003577824}
\ No newline at end of file
+{"COMIRNATY": 0.1473801973628939, "ENOXAPARIN": 25.110916280365636, "SYNAGIS": 32.6368993802519, "null": 3.2242498738564165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2492.json
index da2c1fcf866..60393b77d2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2492.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2492.json
@@ -1 +1 @@
-{"ABILIFY": 1.553262201347113, "ACE": 14.069035486146465, "AERIUS": 1.817596270487612, "APROVEL": 1.2208230274683116, "ARIPIPRAZOLE": 1.1430206592506764, "BORTEZOMIB": 1.856590840553654, "BRINTELLIX": 1.0094846497371628, "BUPRENORPHINE": 2.149674896076566, "CHAMPIX": 2.887547616825142, "CIRCADIN": 3.2616248585858125, "COAPROVEL": 1.4218671729502224, "COLESEVELAM": 151.6179261085339, "COMTAN": 5.110955595625864, "COTELLIC": 1.0919003440803552, "CYMBALTA": 1.7348848264331376, "DULOXETINE": 1.2921776214600094, "EBIXA": 3.7591287089948553, "EMTRICITABINE": 1.115224241740114, "EPIVIR": 2.6282082386729706, "ESOMEPRAZOLE": 1.3151520634186642, "EXVIERA": 1.9390329349265896, "FENTANYL": 1.296538923386267, "FYCOMPA": 1.5083841067668693, "GARDASIL": 1.0663852032919685, "HUMALOG": 1.033062848137882, "HYDROCORTISONE": 1.6822762480211977, "IBUPROFEN": 1.0283194957775907, "KEPPRA": 2.038263789998801, "KYMRIAH": 3.627609349416739, "LACOSAMIDE": 1.1861634848389573, "LANTUS": 1.044130035275224, "LEVETIRACETAM": 1.6789637625293847, "LEVOFLOXACIN": 1.349773702217029, "LYRICA": 3.125634777944516, "MELATONIN": 3.252302476603136, "MICARDIS": 1.0387143361137887, "MIDAZOLAM": 1.781140270047695, "MIRCERA": 1.243854910733728, "NEXAVAR": 1.2824180279429942, "NOT": 1.104545452128398, "NOXAFIL": 1.6283345263825275, "OLANZAPINE": 2.9804685547471754, "OXYBUTYNIN": 2.5741361729414067, "PANTOPRAZOLE": 1.286504543120628, "PEGINTRON": 1.2534763213385367, "PREGABALIN": 1.4140831639398386, "PROTELOS": 2.5225128899865514, "RANEXA": 2.815224351009764, "RISPERIDONE": 1.5529326536496242, "RIVAROXABAN": 2.700465605601525, "SIFROL": 1.623965128971446, "STALEVO": 3.98730445254888, "STIVARGA": 1.0198497135178766, "SUBOXONE": 1.0356275313460628, "SYCREST": 6.522114262989159, "TAMIFLU": 3.3320223622380887, "TELMISARTAN": 1.2078166119029934, "THALIDOMIDE": 2.00625300028967, "TOZINAMERAN": 1.148456699987331, "ULTIBRO": 10.887818752596278, "VALDOXAN": 7.018722659935164, "VFEND": 2.828792059725842, "VIMPAT": 1.8038251207403773, "VORICONAZOLE": 1.3404086731584977, "XTANDI": 1.29113270158352, "XYREM": 1.0989686587207872, "YESCARTA": 4.217527845458372, "ZYPADHERA": 29.82390288543815, "ZYPREXA": 2.227140069878215, "null": 2.1165285530674067}
\ No newline at end of file
+{"INSULIN": 329.14904177587374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2493.json
index 45b1001e63b..27137462bd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2493.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2493.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 95.58470525823957, "CICLOSPORIN": 12.059808396897823, "RITUXIMAB": 77.00236255179288, "TOZINAMERAN": 9.151708164048562}
\ No newline at end of file
+{"null": 0.5899625428937079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2494.json
index caf00fb23b0..8b00f2ea23b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2494.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2494.json
@@ -1 +1 @@
-{"ASPARAGINASE": 490.1458222658583, "CICLOSPORIN": 12.40905736141155}
\ No newline at end of file
+{"COMIRNATY": 0.1830923822339649, "ELIQUIS": 2.84544364858898, "SPIKEVAX": 1.2097771823261647, "VAXZEVRIA": 0.3425951429327853, "ZOSTAVAX": 67.47531042875774, "null": 0.3013992943339894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2495.json
index 377d84c7f66..d87ef63f1c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2495.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2495.json
@@ -1 +1 @@
-{"CELLCEPT": 22.542643091369747, "CICLOSPORIN": 16.613248944557963, "DEXAMETHASONE": 22.331520793197928}
\ No newline at end of file
+{"APIXABAN": 3.507197320821388, "ASPARAGINASE": 10.171756413196482, "COMIRNATY": 1.1464287729022316, "ELIQUIS": 3.2526111649710847, "HUMALOG": 1.5788628543221104, "NOVOSEVEN": 21.579610112702134, "ONCASPAR": 21.4923986331292, "SOLIRIS": 2.853484709085433, "SPIKEVAX": 0.8900975753627091, "SUTENT": 0.7483835468872623, "TOZINAMERAN": 2.5293017842555323, "VAXZEVRIA": 2.0357723748596954, "XARELTO": 8.356462959123247, "null": 0.6074032109554683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2496.json
index 84892f27d15..ba65dce4aae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2496.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2496.json
@@ -1 +1 @@
-{"GANCICLOVIR": 406.71840639623866}
\ No newline at end of file
+{"ABACAVIR": 15.375319019851752, "BIKTARVY": 30.995252689560772, "BUSULFAN": 70.83970378825498, "CAELYX": 51.55851123437852, "CARFILZOMIB": 346.2864830931254, "CELLCEPT": 10.286118901756373, "CICLOSPORIN": 11.549040251041998, "EPIVIR": 90.456990882979, "KALETRA": 23.631283337123367, "null": 0.1038801484150774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2497.json
index 339aa6b92c2..e976ea87dd2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2497.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2497.json
@@ -1 +1 @@
-{"ALIMTA": 4.687109409484428, "APREMILAST": 3.682433240215802, "ASPARAGINASE": 4.76279941265032, "AVASTIN": 8.82674543453865, "AZATHIOPRINE": 2.023234249621292, "BEVACIZUMAB": 1.879284728459444, "BORTEZOMIB": 2.0245072744810626, "BRIDION": 2.0630694988894915, "BUSULFAN": 3.4204300779796397, "CANCIDAS": 6.955663025089515, "CASPOFUNGIN": 6.919115430306952, "CELECOXIB": 1.8357720906699315, "CELLCEPT": 3.873633575106857, "CICLOSPORIN": 3.1366446045320235, "CLOPIDOGREL": 1.0488647403591027, "COMBIVIR": 1.6264751173266492, "CRIXIVAN": 2.632562002279617, "CUBICIN": 5.031266931004899, "CYTARABINE": 3.660186505386039, "DAPTOMYCIN": 8.684994398395828, "DARZALEX": 1.511778995241228, "DEXAMETHASONE": 1.952574856679635, "DOCETAXEL": 1.590371019249912, "EPIVIR": 2.0704977563861364, "ERBITUX": 5.349117565989818, "EXJADE": 1.026553311910772, "FENTANYL": 1.8504167357979204, "GLIVEC": 3.967847195584105, "HALAVEN": 5.112163176540674, "HARVONI": 1.8557647527754035, "HUMAN": 2.753045517383419, "HYDROCORTISONE": 2.2491161818492844, "IBUPROFEN": 1.5366694611383476, "INCIVO": 1.0135283937334147, "INTRONA": 3.195812437602445, "IPILIMUMAB": 1.2109411722840593, "IRESSA": 5.397030623116333, "IRINOTECAN": 1.8614494930016607, "JAKAVI": 1.1806156255501312, "JANUVIA": 1.121533109571845, "JEVTANA": 16.614566679473494, "KEYTRUDA": 3.681532476172509, "KYMRIAH": 4.148602777615936, "LAMIVUDINE": 2.933873924414, "LENVIMA": 2.846569099635216, "LEVOFLOXACIN": 2.343900830570764, "MANNITOL": 8.881459736169768, "MEKINIST": 2.3933374034148223, "METHOTREXATE": 2.1577238682920936, "MIDAZOLAM": 3.650980435261428, "NEXAVAR": 3.661003157919884, "NIVOLUMAB": 6.418862853447184, "NOVOSEVEN": 46.49702813315186, "NOXAFIL": 3.526934410348404, "NPLATE": 1.500913958095063, "OCTREOTIDE": 19.71523571605949, "ONCASPAR": 3.1381527471154307, "OPDIVO": 6.33840348610658, "PACLITAXEL": 3.0054411477035305, "PANTOPRAZOLE": 1.7667585278438105, "PEGASYS": 1.7795532481426477, "PEGINTRON": 2.8599875684713667, "PLAVIX": 1.139027802970158, "REMDESIVIR": 8.639118048273067, "REMICADE": 1.9539907225839848, "ROACTEMRA": 1.9747072989147572, "SOLIRIS": 1.7211033922997654, "SOVALDI": 2.2543983797041407, "STIVARGA": 8.093017908698611, "SUTENT": 2.1244101766053984, "TAGRISSO": 1.197416806338872, "TAMIFLU": 3.397094585647697, "TEMODAL": 4.195681272520557, "TISAGENLECLEUCEL": 38.38684237003344, "TRISENOX": 12.92259288965895, "VEKLURY": 6.695303413776047, "VFEND": 2.297007224643392, "VOTRIENT": 1.0369884167498955, "XELODA": 4.980523480836592, "XOFIGO": 3.432885531902864, "YESCARTA": 3.3469378820965554, "null": 1.864509402202242}
\ No newline at end of file
+{"COMIRNATY": 0.1485098443586269, "DASATINIB": 170.97816419314975, "null": 2.2598474337017564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2498.json
index a28d8723625..74f8f849c1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2498.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2498.json
@@ -1 +1 @@
-{"ASPARAGINASE": 79.74362905613967, "BUSULFAN": 54.0088220720664}
\ No newline at end of file
+{"APIXABAN": 2.410639255740828, "ASPARAGINASE": 13.79892204589274, "COMIRNATY": 1.896023079717144, "HUMIRA": 2.3251700780101854, "METHOTREXATE": 1.3386934759693665, "NOVOSEVEN": 11.29863909780962, "ONCASPAR": 24.661065207642363, "SPIKEVAX": 1.0240794805263074, "TOZINAMERAN": 1.6424652167074651, "VAXZEVRIA": 6.95016248168759, "null": 0.2324870679232522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2499.json
index 900b1653f86..31c8b93fb2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2499.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2499.json
@@ -1 +1 @@
-{"ABACAVIR": 69.60096594591275, "AMIKACIN": 179.9172786839936}
\ No newline at end of file
+{"ASPARAGINASE": 68.8207715845906, "COMIRNATY": 1.2397327854113536, "CYTARABINE": 3.742591659437725, "ENOXAPARIN": 10.756780245405244, "ONCASPAR": 33.36910797971484, "SPIKEVAX": 0.5517997288006646, "TOZINAMERAN": 0.588068189714081, "VAXZEVRIA": 2.771636723059891, "null": 0.700767962075974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/25.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/25.json
index 1542df25182..13eba2ae18b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/25.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/25.json
@@ -1 +1 @@
-{"null": 3.5626190555644883}
\ No newline at end of file
+{"ABACAVIR": 0.3228462862972738, "ABASAGLAR": 0.5812456127222899, "ABATACEPT": 6.659750684260724, "ABILIFY": 0.2289892346004974, "ACETAMINOPHEN": 8.553063250381046, "ACETYLSALICYLIC": 11.778627414771696, "ACTOS": 0.5726278746707198, "ADALIMUMAB": 10.639100003465748, "ADCIRCA": 0.696953426001907, "ADEMPAS": 2.095731150133332, "ADENURIC": 0.592906661902545, "AERIUS": 0.7455502529577069, "AFINITOR": 0.747687066551923, "AGOMELATINE": 2.7221421031876054, "AIMOVIG": 1.0977975808938958, "ALDARA": 0.6529592489208417, "ALEMTUZUMAB": 0.2839713837198455, "ALIMTA": 0.1628744193759824, "ALISKIREN": 2.092793478696998, "ALL": 0.9314412869954912, "AMBRISENTAN": 0.9817822775656188, "AMIKACIN": 0.3966495307601893, "AMINOSALICYLIC": 1.28395375449227, "ANAKINRA": 0.7441068341585323, "ANTIBIOTICS": 1.2526710334592954, "APIDRA": 0.2358905507642127, "APIXABAN": 3.3788916737318813, "APREMILAST": 3.432034511827625, "APREPITANT": 11.366995864393528, "APROVEL": 0.7443884812005871, "ARANESP": 0.1850254070441983, 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2.001633262400938, "CELLCEPT": 0.516033910764978, "CERTOLIZUMAB": 2.05684111721901, "CHAMPIX": 1.2131395385719697, "CICLOSPORIN": 0.3595257432219485, "CIMZIA": 1.8808186197982568, "CLOPIDOGREL": 1.107793199952661, "COAPROVEL": 0.2886990978637173, "COMBIVIR": 0.2607040298889978, "COMIRNATY": 0.410311829423506, "COSENTYX": 1.425353768491585, "CYMBALTA": 0.8456886528214375, "CYTARABINE": 0.1491239536690374, "DESLORATADINE": 0.5964169882704373, "DEXAMETHASONE": 0.3490026675068503, "DOCETAXEL": 0.1636280625267406, "DOXORUBICIN": 0.1663817376899109, "DUAKLIR": 7.370304617312525, "DULAGLUTIDE": 1.6677954232192822, "DULOXETINE": 0.6766865649138798, "DUPIXENT": 1.5823785838042983, "ELIQUIS": 0.4464139905752143, "ELLAONE": 2.9974849293112027, "EMPAGLIFLOZIN": 0.3717517041232922, "EMTRICITABINE": 0.3214898701714604, "ENBREL": 1.651698833161036, "ENOXAPARIN": 0.4619277014676464, "ENTRESTO": 0.5702872375982297, "ENTYVIO": 0.8869235872749074, "ENZALUTAMIDE": 1.0001758240825838, "EPCLUSA": 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1.11794611387913, "ROACTEMRA": 0.2028648406962297, "ROTATEQ": 0.377770826275431, "RUBRACA": 1.1373202926655444, "RUCONEST": 0.5277555424078171, "RUXOLITINIB": 0.661871247875747, "RYBELSUS": 4.928615329065679, "SAXENDA": 1.6693943953716108, "SEMAGLUTIDE": 1.6151863385624396, "SHINGRIX": 0.6340438074954302, "SILDENAFIL": 0.7570054751858033, "SIMPONI": 0.3419714854263966, "SOLIRIS": 0.2871913726339159, "SOVALDI": 0.4397763715865798, "SPIKEVAX": 0.4117934111475204, "SPRYCEL": 0.6793550652943335, "STELARA": 0.3179772817200439, "STIVARGA": 0.1854811119956127, "STRIBILD": 0.104236223200744, "SUBOXONE": 0.670024964593497, "SUTENT": 1.561923856742923, "TACROLIMUS": 0.4743464519967141, "TAGRISSO": 0.4781991602085425, "TAMIFLU": 0.3426454131565856, "TASIGNA": 0.6365585779041907, "TEDUGLUTIDE": 5.104824008091869, "TELMISARTAN": 0.3942220077858853, "TERIPARATIDE": 1.0036381726217445, "TICAGRELOR": 1.0453319801101686, "TOUJEO": 0.5864632588264225, "TOVIAZ": 0.8772633467381832, "TOZINAMERAN": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/250.json
index b777fee9e27..a3cd9e8e2f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/250.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/250.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.1308823610004233, "ABILIFY": 3.349745374987725, "AERIUS": 2.593329495027245, "ALL": 1.680673303578926, "ANTIBIOTICS": 3.16552049140356, "ARIPIPRAZOLE": 4.197341503834913, "ARSENIC": 7.903658225681238, "AZILECT": 2.919359540835329, "BENZODIAZEPINE": 2.5765772321480163, "BENZODIAZEPINES": 7.723144039330642, "BLINDED": 5.973381414487798, "BORTEZOMIB": 1.2749451728167571, "BRINTELLIX": 5.069031777480803, "BRIVARACETAM": 1.7074767988389716, "BRIVIACT": 3.67304783014517, "BUPIVACAINE": 1.577868804981858, "BUPRENORPHINE": 2.207585711126044, "CANNABIDIOL": 7.049334037155823, "CARBIDOPA": 5.122439129672968, "CELECOXIB": 1.3793829935128674, "CHAMPIX": 7.189002809768852, "CIRCADIN": 7.1478951115526215, "CLOPIDOGREL": 1.592032202163621, "COMTAN": 6.700315298240646, "CYMBALTA": 15.249577262316922, "DESLORATADINE": 1.73211253386951, "DEXMEDETOMIDINE": 9.927963903453598, "DULOXETINE": 2.9220561987273146, "EBIXA": 12.37714292818611, "ENTACAPONE": 3.0136677209233658, "EPIDYOLEX": 4.205031584680556, "EXELON": 7.554911944167258, "FENTANYL": 2.5947463163062165, "FYCOMPA": 6.742071344111657, "GANCICLOVIR": 1.699371064368265, "GLIBENCLAMIDE": 1.491708799623617, "GUANFACINE": 11.156048848624554, "IBUPROFEN": 1.661601590208562, "INFANRIX": 1.3161760712037285, "INSUMAN": 2.8593307225004563, "INTEGRILIN": 1.7604741048255637, "INTRONA": 1.2902239643330475, "INVANZ": 4.851999173345048, "INVEGA": 4.644737778963431, "KAFTRIO": 3.207171296121833, "KEPPRA": 4.302283570361107, "KYMRIAH": 1.1332686403902912, "LACOSAMIDE": 2.73725489154508, "LATUDA": 4.095702196641973, "LEVETIRACETAM": 3.474589138694722, "LEVODOPA": 3.450032634703039, "LEVOFLOXACIN": 1.00187773510753, "LOXAPINE": 4.017740379748436, "LURASIDONE": 6.932777359124982, "LYRICA": 2.1496008369226582, "MELATONIN": 3.7786953375078616, "MEMANTINE": 9.545415854045324, "METHYLTHIONINIUM": 13.827537600908707, "MIDAZOLAM": 7.0282104316902245, "NALOXONE": 2.953017410227095, "NOT": 1.2834629203382826, "OCRELIZUMAB": 2.0781078963859687, "OLANZAPINE": 5.860586630882987, "OXYBUTYNIN": 2.423883306611167, "PALIPERIDONE": 4.417861392365098, "PANTOPRAZOLE": 1.028243049731136, "PEGINTRON": 1.379279755243366, "PREGABALIN": 3.620184751892669, "PROPRANOLOL": 1.6341324055055126, "REAGILA": 2.640265235905753, "RISPERIDONE": 5.633948181427527, "ROTARIX": 4.612722887600406, "SELINCRO": 17.25798036615297, "SIFROL": 5.282561823073042, "SLENYTO": 33.4324342605909, "STALEVO": 3.947008318390966, "SUBOXONE": 1.5324844651563132, "SUFENTANIL": 1.193864221690644, "SUSTIVA": 3.851180370650725, "SYCREST": 3.840086729726572, "TAMIFLU": 5.3963347810506255, "TIVICAY": 1.1926544990608925, "TRIUMEQ": 1.2389470483131992, "VALDOXAN": 2.680986286067177, "VARENICLINE": 5.759763586746183, "VFEND": 2.5421991362655345, "VIMPAT": 3.1788310313852857, "VORICONAZOLE": 2.004671025241877, "XYREM": 4.6827162084615965, "YESCARTA": 2.888920676884368, "ZYPADHERA": 16.09520139701912, "ZYPREXA": 4.668850229763304, "null": 2.778574409854176}
\ No newline at end of file
+{"GARDASIL": 54.1932788499651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2500.json
index f9597f5cc84..a9ddd3db92f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2500.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2500.json
@@ -1 +1 @@
-{"BUSULFAN": 701.8897742239742}
\ No newline at end of file
+{"COMIRNATY": 0.0909441942213708, "DARUNAVIR": 85.84375758659355, "null": 2.7784812159855083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2501.json
index 602bcd8337b..6f628a2a9d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2501.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2501.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.220065711603383, "ALEMTUZUMAB": 21.420462696752278, "AZATHIOPRINE": 8.433427005403283, "CELLCEPT": 12.254899719968757, "CICLOSPORIN": 11.277980945457127, "CIMZIA": 6.945541698596145, "DEXAMETHASONE": 7.844528668331018, "EFAVIRENZ": 31.452751516611123, "INFLIXIMAB": 55.729912374370784, "JAKAVI": 15.509153222710976, "LAMIVUDINE": 22.91546804222777, "LEVOFLOXACIN": 11.563651539049122, "METHOTREXATE": 4.364934865312127, "MYCOPHENOLATE": 16.672248245333595, "REMICADE": 41.16119385855462, "SIMPONI": 16.766880983805308}
\ No newline at end of file
+{"COMIRNATY": 0.7907219981453786, "ELIQUIS": 60.56217448874117, "null": 0.239377253921359}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2502.json
index 73bdb62d51f..773b5e4ec79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2502.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2502.json
@@ -1 +1 @@
-{"ZOSTAVAX": 99.54034013877184}
\ No newline at end of file
+{"5AMINOLEVULINIC": 4400.767758996852, "AIMOVIG": 4.0286693249609575, "BENLYSTA": 8.243432857888605, "BUPIVACAINE": 27.71586566220831, "COMIRNATY": 0.1840095424644785, "CYMBALTA": 1.6128084282772548, "FENTANYL": 5.407650892525314, "KEPPRA": 3.124914522970636, "LINACLOTIDE": 982.757957706312, "SPINRAZA": 174.45748391588495, "TOZINAMERAN": 0.5062918430887172, "null": 1.2535714747341495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2503.json
index 5ec85e3542e..d02c14d93cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2503.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2503.json
@@ -1 +1 @@
-{"BREXPIPRAZOLE": 461.80251896243504, "BRINTELLIX": 6.12954912628522, "CHAMPIX": 10.39283276986558, "CYMBALTA": 2.5603851760607035, "DULOXETINE": 7.759396737435632, "GARDASIL": 1.436840644038732, "TOZINAMERAN": 1.0877622393045496, "null": 2.373132342606381}
\ No newline at end of file
+{"ABILIFY": 0.3501397522956079, "ACLIDINIUM": 1.0351970565316555, "ACTOS": 1.3645545077475594, "ACTRAPID": 0.8061064027972268, "ADALIMUMAB": 0.1886388050527251, "ADENURIC": 0.6436002365897966, "AFINITOR": 0.2763642581222467, "AIMOVIG": 1.2430553138902538, "ALIMTA": 0.759239267135077, "ALISKIREN": 10.38804645174454, "AMINOSALICYLIC": 0.2293915241611418, "ANGIOX": 1.8589560897654036, "ANORO": 0.7137122501117027, "APIDRA": 1.854485667791512, "APIXABAN": 0.6084744672365254, "APROVEL": 1.3777225782606528, "ARANESP": 1.0200954773618194, "ARAVA": 0.0568526506468315, "ARIPIPRAZOLE": 0.059954343507356, "ASPARAGINASE": 0.1549460017913705, "ATAZANAVIR": 0.1506716948551487, "ATRIPLA": 0.0454480717233236, "AUBAGIO": 0.96277543725524, "AVANDAMET": 22.68274715899781, "AVANDIA": 24.03301887581649, "AVASTIN": 0.8201979408895876, "AXITINIB": 0.5334461813866546, "AZATHIOPRINE": 0.1372976364680716, "AZILECT": 1.263949718614288, "BARACLUDE": 0.634821907306186, "BC": 8.078284142686709, "BEDAQUILINE": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2504.json
index 983bb708492..4f7cb8d6fae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2504.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2504.json
@@ -1 +1 @@
-{"null": 1.207406696847936}
\ No newline at end of file
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2505.json
index 2a16ab4fee6..463fc11a81d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2505.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2505.json
@@ -1 +1 @@
-{"CHAMPIX": 5.028818683504162, "DULOXETINE": 53.95453967572305, "GARDASIL": 9.51126433642105, "null": 2.7194376992975915}
\ No newline at end of file
+{"null": 0.5959097619204412}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2506.json
index 204eccbb73e..f527a827568 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2506.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2506.json
@@ -1 +1 @@
-{"null": 1.5302196860678896}
\ No newline at end of file
+{"AVANDAMET": 21.709715064212386, "AVANDIA": 13.309273364352492, "BUPRENORPHINE": 4.793130348103876, "CICLOSPORIN": 2.333602606253837, "CLOPIDOGREL": 1.415344463491338, "COMIRNATY": 0.4789144827314201, "ELIQUIS": 2.1657043607925184, "HUMALOG": 1.4657977453286268, "LANTUS": 0.9854280464158812, "SPIKEVAX": 0.1284841882643874, "VAXZEVRIA": 0.2420857203104645, "VIAGRA": 7.518862846846932, "ZOSTAVAX": 2.6236823772618063, "ZYPREXA": 3.912715065415471, "null": 1.4949953758211367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2507.json
index 390829c5e8d..b9239d18208 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2507.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2507.json
@@ -1 +1 @@
-{"KAFTRIO": 742.5940736928019, "ORKAMBI": 172.42963801666235}
\ No newline at end of file
+{"SODIUM": 1687.92266617122, "null": 0.7001484164683186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2508.json
index aa5a2e839bb..55abf69421e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2508.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2508.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 26.59700556124256, "BUDESONIDE": 7.609857396754732, "MELATONIN": 63.75139393289484, "null": 1.6730278900154467}
\ No newline at end of file
+{"null": 0.8658801779225179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2509.json
index d696d46a948..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2509.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2509.json
@@ -1 +1 @@
-{"null": 3.37537800876425}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/251.json
index c0bbf8277cf..0527e767d10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/251.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/251.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 17.284109828083114, "OLANZAPINE": 9.707724095089349, "SUBOXONE": 28.31337205127456, "ZYPREXA": 8.28936972127874, "null": 3.78355831096998}
\ No newline at end of file
+{"BYDUREON": 26.610663768283214, "BYETTA": 220.0514409421921, "JANUMET": 118.25915874205364, "JANUVIA": 87.15553218523193, "VICTOZA": 46.48550131753616, "null": 0.0641788842711177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2510.json
index 40f5b40aa14..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2510.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2510.json
@@ -1 +1 @@
-{"ABILIFY": 1.1395366700004692, "AIMOVIG": 2.743612918391288, "APIXABAN": 4.915530056991187, "ARIPIPRAZOLE": 1.3748726576838672, "AUBAGIO": 1.1020105948006909, "AZILECT": 5.900616285031044, "BOTULINUM": 1.421849860987526, "BRINTELLIX": 1.9492661156696245, "BRIVIACT": 2.0470913145914893, "BUPRENORPHINE": 1.0000164611101834, "CARBIDOPA": 1.4219521628086869, "CHAMPIX": 4.1690783089417485, "CIRCADIN": 2.272031838453262, "COAPROVEL": 1.0687957018203034, "COMIRNATY": 2.06469187703172, "CYMBALTA": 2.700552100368536, "DAKLINZA": 2.031793699430957, "DAPAGLIFLOZIN": 2.8716951937684185, "DESLORATADINE": 2.0283881500139285, "DULOXETINE": 3.5716124085558034, "EBIXA": 1.9167458738968224, "ELLAONE": 2.3586285730297303, "FYCOMPA": 2.109607166475475, "GARDASIL": 4.567871360238483, "JCOVDEN": 2.745208400414902, "KAFTRIO": 3.035506800501325, "KEPPRA": 2.7355719311997437, "LATUDA": 1.4011429115916674, "LEVETIRACETAM": 1.8848294564732104, "LYRICA": 2.1569181712155, "LYSODREN": 5.628209468934589, "MELATONIN": 1.2644249511795105, "MEMANTINE": 1.5051862796408408, "OCRELIZUMAB": 1.8986182594576069, "OLANZAPINE": 1.363730037498886, "OXYBUTYNIN": 1.312554116687139, "PEGASYS": 1.1637188775214862, "PEGINTERFERON": 1.0643472377204766, "PEGINTRON": 1.6882435117701224, "PREGABALIN": 2.4714881848837846, "RISPERIDONE": 1.4407142373962611, "SERTRALINE": 5.686928432736939, "SIFROL": 1.4150218450043703, "SPIKEVAX": 1.3353188798052438, "TIVICAY": 1.6902516180691265, "TOZINAMERAN": 1.0508162864457713, "TWINRIX": 2.025098108605542, "VAXZEVRIA": 1.4475475325704332, "VIMPAT": 1.7417799273575223, "XYREM": 1.6076043728099612, "ZYPADHERA": 3.193905399840759, "ZYPREXA": 1.2391383490180627, "null": 1.0989938328894258}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2511.json
index 449b110b50c..625e1acc395 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2511.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2511.json
@@ -1 +1 @@
-{"BRINTELLIX": 13.768902315861965, "VIAGRA": 22.110168688848745, "null": 3.8228199897022175}
\ No newline at end of file
+{"ZOSTAVAX": 73.72211050037353, "null": 1.1547632322160075}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2512.json
index 4348162aa71..5f62c52503b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2512.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2512.json
@@ -1 +1 @@
-{"ABILIFY": 203.7405551609328, "ARIPIPRAZOLE": 18.907047076525146, "BORTEZOMIB": 33.01067978064694, "OLANZAPINE": 4.405441948850473, "null": 1.6511226516397255}
\ No newline at end of file
+{"GARDASIL": 240.088482691558}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2513.json
index eadc08e0acd..812b3fb9981 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2513.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2513.json
@@ -1 +1 @@
-{"ZOSTAVAX": 81.48589891249225}
\ No newline at end of file
+{"NAGLAZYME": 1075.072725692061, "null": 0.2016999082059885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2514.json
index 132e8ad6c81..8c96365e542 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2514.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2514.json
@@ -1 +1 @@
-{"AVASTIN": 8.203165485461634, "CELLCEPT": 3.966554385145044, "CICLOSPORIN": 2.311585052776248, "CIMZIA": 4.433828401628127, "HUMIRA": 9.91732426285414, "NEXAVAR": 4.79876505324729, "ROACTEMRA": 123.6517494308418, "SUTENT": 2.4188467729249146, "TOCILIZUMAB": 57.97647247760111, "XELJANZ": 1.9791726926284712}
\ No newline at end of file
+{"null": 0.753124490853024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2515.json
index 023a361a96d..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2515.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2515.json
@@ -1 +1 @@
-{"ANAKINRA": 30.81329001782712, "ARAVA": 1.489504525634734, "AVASTIN": 1.2246837530650136, "AZATHIOPRINE": 1.4001909479733063, "BELIMUMAB": 4.885846385773479, "BENLYSTA": 2.693095472601253, "BYETTA": 4.721437047471437, "CELLCEPT": 1.9839707061764331, "CIALIS": 2.856407711537741, "CIMZIA": 1.6642646205615632, "COSENTYX": 2.804862020322839, "ELIQUIS": 1.797665798625831, "ENBREL": 3.057086490494179, "ENTYVIO": 1.1364195854316623, "ESBRIET": 2.553161991828615, "EVISTA": 1.4860115899305948, "EXJADE": 1.1779991620974517, "FIRDAPSE": 3.7990582536834814, "FORSTEO": 1.511564276102059, "HIZENTRA": 3.3385121933344437, "HUMIRA": 2.080586039258766, "HYDROCORTISONE": 1.7114802511000502, "IBRANCE": 2.331372146965253, "INFLIXIMAB": 3.4099816299741588, "INLYTA": 1.225317117313231, "JANUMET": 1.6910824569862843, "JANUVIA": 1.4660307910898338, "LEFLUNOMIDE": 14.45426103677082, "LYRICA": 1.0130395102640315, "MEPOLIZUMAB": 1.1149824335113392, "METHOTREXATE": 4.263534888588175, "NPLATE": 1.0123546694724614, "OFEV": 3.2795509670615868, "OZEMPIC": 13.97869306566334, "REMICADE": 2.292621472783309, "REVATIO": 1.0236965112166343, "RINVOQ": 5.199960889352604, "RITUXIMAB": 1.571217734016368, "ROACTEMRA": 25.154669912635143, "SAXENDA": 3.9104814756767343, "SIMPONI": 3.937419107502691, "STELARA": 3.0252366985001715, "TOCILIZUMAB": 11.816352630252007, "TRELEGY": 1.6395897912291906, "TREMFYA": 3.6364452747953537, "VELTASSA": 1.8561256089093756, "VIAGRA": 1.0160608370040796, "VICTOZA": 1.4345758679645892, "VOTRIENT": 1.6345266818877149, "XELJANZ": 7.399989409912882, "XOLAIR": 1.4083712827921546, "YERVOY": 1.6794317109987558, "ZOSTAVAX": 1.57014365291362, "null": 1.7464218487097756}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2516.json
index e48c556a307..8e4d2e88466 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2516.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2516.json
@@ -1 +1 @@
-{"ELIQUIS": 14.210089769804812, "PLAVIX": 29.5160022152292}
\ No newline at end of file
+{"ADALIMUMAB": 0.868970559994477, "BUSULFAN": 6.9879504237960655, "COMIRNATY": 0.1226021983273019, "GARDASIL": 222.5649834247455, "LAMIVUDINE": 17.016252262998087, "LEMTRADA": 11.28306537349636, "SILGARD": 309.445057320626, "STELARA": 6.370602367375184, "null": 0.3819786695260659}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2517.json
index d4d2168bac0..c8093e2a3e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2517.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2517.json
@@ -1 +1 @@
-{"RINVOQ": 95.70263287671716}
\ No newline at end of file
+{"NORVIR": 116.0334952499294, "null": 1.7386460006666429}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2518.json
index cc2a74223e4..785b806c587 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2518.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2518.json
@@ -1 +1 @@
-{"ARANESP": 1.5227612162440416, "BUDESONIDE": 1.5578358965122274, "BYDUREON": 2.6846459932199074, "BYETTA": 8.88894968086237, "CELLCEPT": 1.9073265088799085, "CLOPIDOGREL": 1.1705898477551002, "ELIQUIS": 2.240109254684085, "ENBREL": 1.0968228306859376, "EVISTA": 2.9710420481092594, "FORSTEO": 1.1444359508322473, "HUMIRA": 2.385131762101803, "HYDROCORTISONE": 5.198682800146693, "IBUPROFEN": 1.3108513815376786, "JANUMET": 10.427998186122958, "JANUVIA": 8.774352220282179, "PLAVIX": 2.6408760654630403, "RINVOQ": 2.5944385848836133, "ROACTEMRA": 4.385108878102787, "TASIGNA": 1.5670005680966497, "XELJANZ": 2.3447556565832035, "ZOSTAVAX": 3.8329047830558176, "null": 4.010707104851753}
\ No newline at end of file
+{"null": 1.591119721647931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2519.json
index 8c3431b1a8d..801082a251d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2519.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2519.json
@@ -1 +1 @@
-{"ARANESP": 4.80085744929904, "BYETTA": 9.519097822420362, "CLOPIDOGREL": 2.226328070478785, "ELIQUIS": 1.6148780257069848, "ENTRESTO": 1.698170953908823, "JANUMET": 18.433687217587597, "JANUVIA": 11.855539869561465, "PANTOPRAZOLE": 3.407102626698349, "ROACTEMRA": 3.3951013805874832, "ZOSTAVAX": 3.1507552693242835, "null": 4.497157838323047}
\ No newline at end of file
+{"ATRIPLA": 3.4669962240959498, "COMIRNATY": 1.7374401012301215, "SPIKEVAX": 0.7575801503471842, "TRUVADA": 1.486700068113858, "VAXZEVRIA": 0.2181937547962925, "ZOSTAVAX": 33.08562295128034, "null": 0.5502275798566906}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/252.json
index c19a26f6093..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/252.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/252.json
@@ -1 +1 @@
-{"CELLCEPT": 71.77106590409363, "null": 2.5460556445726743}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2520.json
index 2a3b9be554a..5a544807a8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2520.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2520.json
@@ -1 +1 @@
-{"BRILIQUE": 6.518462666768117, "CLOPIDOGREL": 23.18386310420243, "EFIENT": 98.73199944516794, "ELIQUIS": 33.00622663968115, "LIXIANA": 20.619695137050822, "NEXAVAR": 2.33225968549136, "PLAVIX": 31.835245275498075, "RINVOQ": 6.458060957101545, "XARELTO": 52.14436765853645}
\ No newline at end of file
+{"ATRIPLA": 6.869731972045208, "COMIRNATY": 0.177555431893149, "NAGLAZYME": 141.75257451018143, "TRUVADA": 3.077848270211893, "ZOSTAVAX": 15.011340115978092, "null": 0.5768253248112127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2521.json
index 42494249169..1ffb3392038 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2521.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2521.json
@@ -1 +1 @@
-{"null": 2.7801871827442293}
\ No newline at end of file
+{"ATRIPLA": 5.562755034391413, "ELIQUIS": 4.369895379538706, "EVISTA": 19.59345017112809, "FORSTEO": 4.110897482964797, "HUMALOG": 3.6205491175687423, "HUMIRA": 4.328709610487277, "IBRANCE": 1.9845264113147807, "KEPPRA": 2.0913302079384315, "LANTUS": 2.0407506765239884, "STELARA": 1.824543413926444, "STRIBILD": 4.16721827273374, "TRUVADA": 3.1802554862285124, "VIAGRA": 8.823489078847313, "null": 1.066430489345506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2522.json
index 9a703b2bca3..32a02cc67f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2522.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2522.json
@@ -1 +1 @@
-{"ACE": 1.2113001525920923, "ACETYLSALICYLIC": 2.223114597294125, "ACTRAPHANE": 1.3404414129990312, "ADEMPAS": 1.5341988087398366, "AIMOVIG": 1.1692676998619225, "ALENDRONATE": 1.710558124439637, "AXURA": 2.466106202453957, "AZILECT": 1.0680085184000712, "BETMIGA": 2.0706440640635884, "BREXPIPRAZOLE": 1.063503052860156, "BRINTELLIX": 1.8165878159708075, "BRIVIACT": 1.325328283631462, "CARBIDOPA": 1.2993995373532103, "CELECOXIB": 1.368226904600141, "CEREZYME": 5.155105603791653, "CERVARIX": 1.1619578812311535, "CHAMPIX": 1.2011662989014196, "CHORIOGONADOTROPIN": 1.4599228217660942, "CIRCADIN": 1.330745181470879, "CLOPIDOGREL": 1.0915833204187877, "COAPROVEL": 1.038153666587851, "COMIRNATY": 1.8567582925992467, "COVID19": 1.99720124338321, "CYMBALTA": 2.2598958094633668, "DAFIRO": 2.4752661277959533, "DOFETILIDE": 1.6485087187447698, "DRUG": 1.2238680110923053, "ELLAONE": 1.846784489882293, "ENTRESTO": 1.8895835003248709, "ESBRIET": 1.232307316329999, "ESMYA": 1.2752569824837352, "EXFORGE": 1.7647237421357105, "FAMPRIDINE": 1.0195922235578734, "FAMPYRA": 2.0183628388931005, "FLUCELVAX": 1.1146737820062702, "FORSTEO": 1.9935024815245532, "FYCOMPA": 1.9871790785389345, "GARDASIL": 2.31921778540995, "GILENYA": 1.113529651317713, "GREPID": 2.3832392380405856, "GUANFACINE": 1.0305106882199178, "HYDROCHLOROTHIAZIDE": 1.634226155891691, "IRBESARTAN": 1.106161165110791, "IVABRADINE": 1.8070006095957425, "JCOVDEN": 2.6086307923131318, "KARVEA": 1.7155745658040162, "KARVEZIDE": 1.7422015680497285, "KENTERA": 1.3467405525421623, "KINZALMONO": 1.7852686395613797, "LIXIANA": 1.499080187650656, "LUMINITY": 2.903327044432503, "LYRICA": 1.1412452349666604, "LYSODREN": 1.2450224442502713, "MELATONIN": 1.1510168645257228, "MEMANTINE": 1.1978186668562822, "MENVEO": 1.4372388959710538, "MICARDIS": 1.4599156939842954, "MICARDISPLUS": 1.5238347396213936, "MOVYMIA": 3.0104961643709407, "NIMENRIX": 1.7241445322213962, "OCRELIZUMAB": 1.4957864482467291, "PAXLOVID": 1.1760624342543784, "PERAMPANEL": 1.4679224368031527, "PRAMIPEXOLE": 1.4560674948721517, "PREOTACT": 1.8471101228917213, "PRITORPLUS": 1.0194031673028885, "RANEXA": 4.163421604969596, "RANOLAZINE": 2.4691724897702443, "RAPISCAN": 3.008945610127116, "RASILEZ": 1.136381448042306, "REBLOZYL": 2.026849927475605, "REGADENOSON": 2.141413942198809, "RYBELSUS": 1.0919144090160957, "SAXENDA": 1.0701755305874312, "SIFROL": 1.091397728681303, "SILODYX": 2.793465152464892, "SPIKEVAX": 1.592017204565009, "SPIRONOLACTONE": 1.1714468984530693, "STOCRIN": 1.148678503155791, "TEKTURNA": 1.0708137014797177, "TELMISARTAN": 1.21633732319385, "TERIPARATIDE": 1.1265421751115403, "TERROSA": 2.975380818238293, "TICAGRELOR": 1.5599295507111124, "TOZINAMERAN": 1.9226438455920396, "TWINRIX": 1.4738196235565173, "TWYNSTA": 1.3703168534369556, "UROREC": 3.805618341467909, "VALSARTAN": 2.4139221138168327, "VAXZEVRIA": 1.803750736754348, "VIMPAT": 1.685743425418662, "XTANDI": 1.1999368333323726, "ZYPADHERA": 2.9243051032934058}
\ No newline at end of file
+{"GARDASIL": 20.396950832593944, "null": 0.9819335484950265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2523.json
index 69acc23e768..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2523.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2523.json
@@ -1 +1 @@
-{"AMBRISENTAN": 209.7620579019165, "COMIRNATY": 1.3151910652387002, "COVID19": 3.819390747448455, "LYRICA": 9.743700679808548, "SPIKEVAX": 1.4567542332668864, "TOZINAMERAN": 3.270550566860888}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2524.json
index 2de66ae6735..8e46b140fd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2524.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2524.json
@@ -1 +1 @@
-{"APIDRA": 1.2650879019764316, "BRILIQUE": 1.4499800087436787, "CLOPIDOGREL": 1.4567513700636396, "COVID19": 7.544912524377589, "ENTRESTO": 4.6962221369103645, "ESOMEPRAZOLE": 1.7097705335438187, "EXFORGE": 1.0123723446078534, "GARDASIL": 2.8182796627603803, "NIMENRIX": 1.9048156553166204, "OMALIZUMAB": 1.0664823970017592, "OPSUMIT": 2.294030732177548, "OXYBUTYNIN": 3.83776226896576, "TOZINAMERAN": 4.183841278010476}
\ No newline at end of file
+{"COMIRNATY": 3.535282873033508, "GARDASIL": 3.1818444584995884, "MODERNA": 9.523450420830487, "SPIKEVAX": 0.9456545095487676, "VAXZEVRIA": 0.6030953335718479, "null": 0.4350622345425629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2525.json
index 5e2389a6180..c92fdb7fd27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2525.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2525.json
@@ -1 +1 @@
-{"null": 10.625589676789732}
\ No newline at end of file
+{"AIMOVIG": 71.70047280177272, "COMIRNATY": 0.9105816347699812, "VAXZEVRIA": 1.5609438437969938, "null": 0.2519281267143138}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2526.json
index 624170e33ad..cebd9d673c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2526.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2526.json
@@ -1 +1 @@
-{"null": 1.731601702195374}
\ No newline at end of file
+{"CELLCEPT": 4.425053955395272, "CIMZIA": 1.459945557370823, "COMIRNATY": 0.0488589268647384, "GARDASIL": 25.623608003271865, "SIMPONI": 2.7778310382755245, "STELARA": 1.9746516332505624, "XELJANZ": 1.951583590444228, "null": 2.2597895430359465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2527.json
index 969ea51e193..8b253da507a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2527.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2527.json
@@ -1 +1 @@
-{"CARBIDOPA": 182.7407884871538, "ENTACAPONE": 672.2742716305228, "LEVODOPA": 2264.228123339601, "STALEVO": 223.59585536084668}
\ No newline at end of file
+{"GARDASIL": 171.54689905781538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2528.json
index a389aab4509..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2528.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2528.json
@@ -1 +1 @@
-{"null": 2.780840424534706}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2529.json
index 8a7035ff893..1dd61023736 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2529.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2529.json
@@ -1 +1 @@
-{"null": 2.9195418840675096}
\ No newline at end of file
+{"GARDASIL": 21.18155176500074, "RITUXIMAB": 23.67304750201344, "null": 0.9627381457578568}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/253.json
index 4229ebb01f8..33000839fc0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/253.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/253.json
@@ -1 +1 @@
-{"null": 1.237937827328386}
\ No newline at end of file
+{"COMIRNATY": 1.0089374572480323, "null": 1.5498503502753511}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2530.json
index 1610568f6ea..e6e67aee351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2530.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2530.json
@@ -1 +1 @@
-{"COVID19": 1.4126208014716917, "null": 1.1072908406603856}
\ No newline at end of file
+{"null": 1.5228310199198265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2531.json
index ae1e1953fea..2d25fea8fb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2531.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2531.json
@@ -1 +1 @@
-{"ABILIFY": 3.2572314748298234, "AIMOVIG": 1.6335839795568048, "ARIPIPRAZOLE": 5.505312935719867, "GARDASIL": 2.0679736900465224, "KEPPRA": 3.611049959182215, "LATUDA": 10.254229855473769, "LEVETIRACETAM": 3.07628284858598, "MMRVAXPRO": 6.935784455908836, "OLANZAPINE": 3.4997817277510266, "TOZINAMERAN": 1.1552132482516977, "ZYPREXA": 10.59189724131937, "null": 2.388198772813209}
\ No newline at end of file
+{"null": 2.212712716221833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2532.json
index 421a84beb05..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2532.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2532.json
@@ -1 +1 @@
-{"FORSTEO": 12.753593277078698, "KEPPRA": 6.2628449371298265, "LEVETIRACETAM": 15.394828611129451, "VIMPAT": 21.328565401013428, "null": 1.6422139714977595}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2533.json
index 4c2654341e8..c1c8906f1ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2533.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2533.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 11.926260110277816, "GARDASIL": 3.357622485606285, "null": 2.0038374546137248}
\ No newline at end of file
+{"null": 0.809811682955197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2534.json
index b8b93d10bf2..b30067de1a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2534.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2534.json
@@ -1 +1 @@
-{"ABILIFY": 1.6175402998597077, "ALLI": 11.680945098091678, "ARIPIPRAZOLE": 3.426287647501729, "ASENAPINE": 17.210980663496287, "BENZODIAZEPINE": 50.48282359227272, "BENZODIAZEPINES": 21.311868883850032, "BUPRENORPHINE": 21.72410629812369, "CAFFEINE": 25.059676152125206, "CANNABIDIOL": 17.285453545261063, "DULOXETINE": 3.4659486246452924, "EFAVIRENZ": 2.585471618930736, "ENTACAPONE": 2.378851309861442, "FENTANYL": 17.29344793210555, "IBUPROFEN": 3.329767673530079, "INVEGA": 1.522019633781727, "LEVETIRACETAM": 1.8247051648162944, "LEVODOPA": 3.159321513760441, "LEVOFLOXACIN": 1.322057450046464, "LOXAPINE": 15.312618666358835, "LYRICA": 4.529409275825149, "MELATONIN": 1.3294343017312449, "MIDAZOLAM": 3.74175798285502, "MUSCLE": 72.59094091393193, "NALOXONE": 5.4057542540033925, "NOT": 8.004700452066203, "OLANZAPINE": 4.671947589421734, "OPIACE": 90.323352896149, "OPIOID": 43.20457782376957, "OPIOIDS": 32.69048150657904, "OTHER": 7.128216886330796, "OXYBUTYNIN": 2.3103916557890805, "PALIPERIDONE": 3.801343130606583, "POPPERS": 128.15299715990255, "PREGABALIN": 18.82519772823964, "PTC": 113.0037911801918, "RISPERIDONE": 1.7768276073362907, "SILDENAFIL": 1.9816298085491315, "SODIUM": 8.448666755634182, "SOMATROPIN": 4.682739818575517, "SUBOXONE": 12.366158419340175, "SUBSTANCE": 86.9809708477372, "TESTOSTERONE": 12.984058523005102, "UNKNOWN": 2.931927045546745, "UNSPECIFIED": 11.469858188622805, "XYREM": 2.331073061463816, "null": 7.065219516060858}
\ No newline at end of file
+{"null": 1.5854742411385632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2535.json
index dcff8fa1719..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2535.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2535.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 19.704887253230016, "LYRICA": 4.990519418258603, "null": 12.346806829450482}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2536.json
index 765a67d98e5..c794fbce591 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2536.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2536.json
@@ -1 +1 @@
-{"INSULIN": 77.0786016108551, "null": 1.8340784032058013}
\ No newline at end of file
+{"COMIRNATY": 0.8338808262648115, "KAFTRIO": 247.60721129326456, "SPIKEVAX": 0.4466857166924279, "ZOSTAVAX": 8.40870162129796, "null": 0.473231524436577}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2537.json
index 7821ad07483..3543ee43ad3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2537.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2537.json
@@ -1 +1 @@
-{"null": 12.201030850933437}
\ No newline at end of file
+{"BRIVIACT": 211.97863648775075, "KEPPRA": 34.78367373933861, "LEVETIRACETAM": 33.00445893528884, "VIMPAT": 109.98365812863648, "null": 1.325585166980281}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2538.json
index 64e79567d45..70b227a9a8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2538.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2538.json
@@ -1 +1 @@
-{"ASPARAGINASE": 41.24009998524599, "DEXAMETHASONE": 12.770183216085057, "METHOTREXATE": 20.15825378359944, "TOBRAMYCIN": 142.21029874448897, "null": 1.2686457313748454}
\ No newline at end of file
+{"null": 1.839196798798022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2539.json
index 06225813ac8..7bd2cc8287f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2539.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2539.json
@@ -1 +1 @@
-{"BYDUREON": 43.58628376827056, "FIASP": 77.45257335122263, "SAXENDA": 10.475156925010918, "SIMPONI": 9.260663263915555, "null": 5.12370747165833}
\ No newline at end of file
+{"COMIRNATY": 0.3818529906857005, "PEGASYS": 1.5880835679966507, "SPIKEVAX": 0.2040244013480626, "SUTENT": 1.548684582993325, "TOZINAMERAN": 0.6203202503952023, "VAXZEVRIA": 0.4468529792213651, "XELJANZ": 3.929528499437677, "null": 1.717825925148238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/254.json
index 8baebee2bc7..3e5b332b264 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/254.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/254.json
@@ -1 +1 @@
-{"null": 2.1487608395327937}
\ No newline at end of file
+{"null": 2.5342311463149105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2540.json
index 88c7aeaa3e5..d7341a9c617 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2540.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2540.json
@@ -1 +1 @@
-{"BETAFERON": 9.141797321708395, "BUPIVACAINE": 8.137558355126385, "BYDUREON": 8.673766473765868, "METHOTREXATE": 1.565168346537427, "NEULASTA": 3.022838220860692, "PLEGRIDY": 608.044630785028, "ROACTEMRA": 4.033659416823783, "SIMPONI": 287.3404709635233, "STELARA": 5.531785482182477, "TREMFYA": 45.04534043535944}
\ No newline at end of file
+{"AFINITOR": 2.9392651027138585, "COMIRNATY": 0.2995318526833339, "GARDASIL": 1.786348115569935, "IBRANCE": 1.7467421588613847, "PEGASYS": 2.70185097197796, "PEGINTRON": 2.800322583820305, "ROTATEQ": 8.18730910684673, "SPIKEVAX": 0.2933074979815914, "SUTENT": 5.867529615773645, "TOZINAMERAN": 0.7144942652076004, "VAXZEVRIA": 0.2141325172438469, "null": 1.620065230890832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2541.json
index 8213588c01f..fe9fb53e246 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2541.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2541.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 68.49806078669826, "null": 4.570305539412523}
\ No newline at end of file
+{"LANTUS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2542.json
index 680a0e6f752..6e9a90c4c7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2542.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2542.json
@@ -1 +1 @@
-{"ACETAMINOPHEN/OXYCODONE": 197.37695047392972, "ANTIDEPRESSANTS": 17.39829051045501, "ARIPIPRAZOLE": 2.3615565393201656, "AZATHIOPRINE": 1.077753388017313, "BENZODIAZEPINE": 9.552223164224207, "BENZODIAZEPINES": 4.937416434744581, "BUMETANIDE": 2.483385532904476, "BUPRENORPHINE": 86.15548549958771, "BUVIDAL": 4.887444626431577, "CAFFEINE": 6.506951319547394, "CANNABIDIOL": 6.837390555835788, "DENOSUMAB": 1.6250584903266867, "DULOXETINE": 1.661616701786229, "ENBREL": 1.791883274661369, "FENTANYL": 11.887994963104846, "LEVODOPA": 3.5291502802900347, "LYRICA": 4.188824040832167, "MIDAZOLAM": 1.9282107228091143, "NALOXONE": 2.240456040552168, "OPIOIDS": 30.465534988836197, "POPPERS": 7.356793977485433, "PREGABALIN": 6.755600760859724, "RISPERIDONE": 1.423547357429495, "SIFROL": 1.2038729384468754, "SPIRONOLACTONE": 1.4898482670348083, "SUBOXONE": 19.692413235083755, "SUBSTANCE": 7.616059680106968, "TOVIAZ": 1.4356397620329713, "VIAGRA": 1.5813359647657692, "null": 5.892711789397809}
\ No newline at end of file
+{"AMIKACIN": 8.653335205272196, "CHAMPIX": 1.074534934671723, "CLOPIDOGREL": 1.130794566262385, "COMIRNATY": 0.3809999011942513, "IBRANCE": 1.846591710207974, "KEYTRUDA": 2.0514852323936563, "METHOTREXATE": 5.038505493987363, "NEXAVAR": 1.8734533819168997, "OLYSIO": 17.171008689501928, "PEGASYS": 0.530805564981007, "PLAVIX": 1.253178842912787, "SPIKEVAX": 0.2497597403045995, "SUTENT": 1.6780757308259442, "TOZINAMERAN": 0.5541110544184139, "VAXZEVRIA": 0.3612293165261982, "VFEND": 13.293593542138376, "null": 1.9283284792801128}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2543.json
index a81b0114c22..c2f9fc89b44 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2543.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2543.json
@@ -1 +1 @@
-{"null": 2.6556073102073143}
\ No newline at end of file
+{"null": 7.510324627111727}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2544.json
index f1db4ec940f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2544.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2544.json
@@ -1 +1 @@
-{"BENZODIAZEPINE": 50.371841410850855, "BUPRENORPHINE": 62.7676433318373, "FENTANYL": 24.90546835726349, "SUBOXONE": 391.7403601354425}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2545.json
index 39cd4a0eb29..36692cb9d78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2545.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2545.json
@@ -1 +1 @@
-{"DAPTOMYCIN": 1786.848880883941, "null": 1.3537446484162512}
\ No newline at end of file
+{"null": 4.140491715066219}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2546.json
index 424fea7a4cc..496427b39df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2546.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2546.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 28.714541858225896, "FENTANYL": 16.69725031820183, "LYRICA": 5.609046106753419, "MIDAZOLAM": 7.726450048267389, "PREGABALIN": 8.132524143270455, "SAXENDA": 7.625587751494669, "SUBOXONE": 58.92824727539924, "null": 4.189458598481271}
\ No newline at end of file
+{"null": 6.384479587378612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2547.json
index 12bb57216ea..6dcb50b7920 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2547.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2547.json
@@ -1 +1 @@
-{"AIMOVIG": 77.35683228485748, "APIDRA": 5.867757818378583, "ARANESP": 4.725081980372287, "BIRESP": 1047.2784940604204, "BYDUREON": 19.687545885695517, "COSENTYX": 6.135189950199675, "FASENRA": 40.254897162202646, "LANTUS": 3.3367689032953423, "NEULASTA": 26.08128750248776, "PLEGRIDY": 80.633419184464, "TOUJEO": 11.456468695840517, "null": 2.407482081097301}
\ No newline at end of file
+{"null": 5.565767298803403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2548.json
index dd9dc6463e6..a7d5bfe98c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2548.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2548.json
@@ -1 +1 @@
-{"IBUPROFEN": 12.8503836098202, "REAGILA": 523.1307302031682, "SAXENDA": 77.11765511333691, "VICTOZA": 85.72400872359394, "null": 1.2557161798810734}
\ No newline at end of file
+{"null": 4.644449305737621}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2549.json
index b4b7c51bb8b..8ac3105c02c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2549.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2549.json
@@ -1 +1 @@
-{"AIMOVIG": 3.669005170764745, "BENLYSTA": 4.850461765358749, "BUPRENORPHINE": 5.539856056226332, "CIALIS": 45.5102683415831, "COSENTYX": 3.0372034535735777, "ENTYVIO": 18.34997703813664, "EVENITY": 11.829188906857402, "FASENRA": 13.273678429179885, "FESOTERODINE": 154.80469089025684, "NOVORAPID": 6.99623203876677, "PREGABALIN": 8.099993366020223, "SAXENDA": 13.47457734922356, "SUBOXONE": 12.662908831845307, "XELJANZ": 2.338501716279556, "null": 1.608171677011033}
\ No newline at end of file
+{"null": 4.3593139447282905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/255.json
index fd0a9661865..071a662d5fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/255.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/255.json
@@ -1 +1 @@
-{"MIRCERA": 378.5960489497312}
\ No newline at end of file
+{"NAGLAZYME": 117.32806557153818, "null": 2.3301800368383194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2550.json
index c26b2d1f6ab..bf7cf95d918 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2550.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2550.json
@@ -1 +1 @@
-{"ABILIFY": 4.502342035523024, "ARIPIPRAZOLE": 2.2516969855361, "HUMAN": 131.82840939780604, "IBRANCE": 1.599788165966794, "KEYTRUDA": 4.97084235701894, "LACOSAMIDE": 9.19346987839598, "LATUDA": 9.497261143728627, "LEVETIRACETAM": 2.6453370919791683, "LOPINAVIR": 23.15583204073633, "MELATONIN": 18.2963542504378, "NUCALA": 2.2245982795728616, "PEMBROLIZUMAB": 15.535301193842452, "RAPAMUNE": 12.753466944716411, "RELVAR": 8.500690464997428, "RITUXIMAB": 2.858437953108741, "VIAGRA": 5.650401654667255, "XELJANZ": 13.777299223054897, "null": 1.86183702408808}
\ No newline at end of file
+{"null": 1.820352752819057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2551.json
index 14fed1f188e..d46cc5b736b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2551.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2551.json
@@ -1 +1 @@
-{"ABATACEPT": 1.749083897660009, "ADALIMUMAB": 1.9624068157350063, "ALIMTA": 2.247294419904118, "AMIKACIN": 1.6842263518506149, "APREMILAST": 5.853536931596886, "ARAVA": 1.2353163559817792, "AXITINIB": 1.752634396443986, "BARACLUDE": 2.3097560264678463, "BORTEZOMIB": 1.480930874910334, "BOSULIF": 1.006527312571162, "BRAFTOVI": 1.0635756341800169, "BRILIQUE": 1.166440732440117, "CANCIDAS": 1.3633725469841853, "CELECOXIB": 2.752022883602856, "CICATRIZANTS": 95.08060263820587, "COTELLIC": 1.5460992705855865, "CUBICIN": 3.2501904107130817, "DAPAGLIFLOZIN": 3.393848503760205, "DAPTOMYCIN": 5.991722358882518, "EFAVIRENZ": 1.3211296218663082, "EFIENT": 3.514184810299948, "EMEND": 3.061240749645224, "EMTRICITABINE": 1.258984382979017, "ENBREL": 5.334107404167554, "ERLEADA": 12.93590459405275, "ESOMEPRAZOLE": 2.120937576076269, "FEBUXOSTAT": 8.88118744589666, "FORXIGA": 1.3293770875212771, "FYCOMPA": 4.319073140031302, "GLIVEC": 1.764335830646136, "HALAVEN": 1.1167262576631594, "HERCEPTIN": 1.046726730644323, "HUMIRA": 1.1518300601700355, "IBUPROFEN": 2.0120722322588747, "INCIVO": 3.0433723786696665, "IPILIMUMAB": 1.7353720148859586, "IRESSA": 2.6541288295745358, "JANUVIA": 1.414055651254689, "KAFTRIO": 4.402742838133394, "KEYTRUDA": 2.7352618133793123, "LENVIMA": 2.1347704191464043, "LEVETIRACETAM": 2.147818082036029, "LEVOFLOXACIN": 5.227316988337027, "MICARDIS": 4.733788404851223, "NEXAVAR": 3.1744324025329207, "NORVIR": 1.9955542966360755, "NOT": 1.8592109107574344, "NOXAFIL": 2.432980672758028, "OPDIVO": 5.390890298927222, "PACLITAXEL": 1.1945054120366636, "PEGINTERFERON": 4.110204965752982, "PEGINTRON": 4.672010911985311, "PEMBROLIZUMAB": 1.7035002682355225, "PEMETREXED": 1.1835516787147142, "PLAVIX": 1.550856730721233, "POTELIGEO": 46.130976230340174, "PREGABALIN": 1.0003506776542055, "PROTELOS": 2.601705222846117, "RASILEZ": 1.3422733671950595, "REBETOL": 2.320608739067075, "REVLIMID": 1.973124660089819, "STIVARGA": 7.083534351605588, "TAGRISSO": 2.929434774742854, "TAMIFLU": 6.608636102100278, "TEMODAL": 4.61005253150852, "TEMOZOLOMIDE": 1.9416843992263784, "UNKNOWN": 9.09065494289497, "VFEND": 2.138180879813949, "VIMPAT": 2.218860511221159, "VIRAMUNE": 2.441888774818128, "ZELBORAF": 1.5187868968123583, "ZONISAMIDE": 7.800527925233679, "null": 2.6447027181899867}
\ No newline at end of file
+{"null": 8.063700364016269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2552.json
index ee6ce20d991..2be150b902a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2552.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2552.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 16.82372605027741, "FILGRASTIM": 323.0463228627666, "GARDASIL": 5.386528222966223, "LEMTRADA": 93.84634169618052, "PEGINTRON": 8.69825360655664, "STELARA": 5.010723766828972}
\ No newline at end of file
+{"null": 2.6688524051495253}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2553.json
index de9c6f40d66..5f5399e1627 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2553.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2553.json
@@ -1 +1 @@
-{"null": 1.9607734296071424}
\ No newline at end of file
+{"SUBSTANCE": 19458.108500057097, "null": 2.4093840112902654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2554.json
index 4d17ebfdf82..176db279f31 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2554.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2554.json
@@ -1 +1 @@
-{"null": 1.4303389403425195}
\ No newline at end of file
+{"null": 0.9188862646726608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2555.json
index d0fb77a6b9d..840d125d8d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2555.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2555.json
@@ -1 +1 @@
-{"ABACAVIR": 8.931655246947033, "ABASAGLAR": 2.5685925801274303, "ABATACEPT": 6.375439571464654, "ACETYLSALICYLIC": 12.516584371520928, "ACTRAPID": 4.199132643288808, "ADALIMUMAB": 6.774836574416705, "ADCIRCA": 2.5610156637265917, "ALBIGLUTIDE": 13.348327111296932, "ALL": 3.0030386377431832, "AMBRISENTAN": 1.4074420758478998, "AMIKACIN": 1.0625637640986323, "AMINOSALICYLIC": 1.6212969241442745, "ANAKINRA": 11.26621782250936, "ANTIBIOTICS": 1.6210999599791545, "ANTIHYPERTENSIVES": 8.843767800274412, "APIDRA": 1.3665579122529994, "APREMILAST": 11.75709119040272, "APREPITANT": 2.810212022339558, "ARANESP": 8.809794231668283, "ARAVA": 6.205757257189551, "ASPARAGINASE": 2.3654487674411824, "AVAMYS": 3.273125281812124, "AZATHIOPRINE": 4.083193918170512, "AZTREONAM": 3.365402598431708, "BELIMUMAB": 1.0539315252911905, "BRIDION": 3.659927077364237, "BUDESONIDE": 2.7920262670521967, "C1": 11.280292227795975, "CEFUROXIME": 4.252496186615889, "CELECOXIB": 3.596543828674449, "CERTOLIZUMAB": 4.546215026516102, "CICLOSPORIN": 1.0544346663526214, "CIMZIA": 2.966083482676343, "CLINDAMYCIN": 18.63975385307859, "COSENTYX": 2.3337439615204767, "DAPAGLIFLOZIN": 1.2421842883921932, "DAPTOMYCIN": 1.7199970404185163, "DARBEPOETIN": 2.510450706629234, "DESLORATADINE": 2.946506145206897, "DEXAMETHASONE": 1.0521075170530532, "DOLUTEGRAVIR": 1.1777717320789545, "DULAGLUTIDE": 2.3909662061345096, "DULOXETINE": 1.4301515625570544, "DUPIXENT": 5.401512033901239, "ENBREL": 10.07482545455558, "ENOXAPARIN": 1.272430414726597, "ENTECAVIR": 1.1029874146809644, "ENTYVIO": 2.294126974687248, "ETANERCEPT": 1.6879889298850808, "FASENRA": 1.3190975310702868, "FENTANYL": 1.0674142585115909, "FLUTICASONE": 2.4333965565999502, "GREPID": 6.644100079975162, "HUMALOG": 2.281798921261733, "HUMIRA": 6.48584573273197, "HYDROCHLOROTHIAZIDE": 1.0371852185095085, "HYDROCORTISONE": 2.152735140128359, "IBUPROFEN": 3.204526833778009, "INCRUSE": 1.1015507007953589, "INFLECTRA": 3.279135469330865, "INFLIXIMAB": 4.842428104319109, "INSULIN": 3.079063954170403, "INVOKANA": 1.602181158467035, "IRON": 2.025163195910404, "LEFLUNOMIDE": 3.047417980423731, "LEVEMIR": 1.7870027420847636, "LEVOFLOXACIN": 2.875681206602871, "LYRICA": 2.089346387331452, "MEPOLIZUMAB": 2.3159257202602643, "METFORMIN": 1.950981162837244, "METHOTREXATE": 1.9319212939213164, "MIRCERA": 63.10504240921421, "MIXTARD": 1.4585375552646205, "NALOXONE": 3.2856144298734145, "NOT": 1.2814312547940725, "NUCALA": 1.1042875750750891, "OCRELIZUMAB": 2.3120015287754905, "OMALIZUMAB": 12.101184423592176, "ONCASPAR": 2.3823726608308453, "ORENCIA": 8.396550816373425, "OSELTAMIVIR": 1.421015612871123, "OTEZLA": 4.151935281439509, "OXYBUTYNIN": 2.0179228833259284, "PANTOPRAZOLE": 1.2322283713396072, "PRIVIGEN": 1.1611736393415772, "PROPRANOLOL": 1.6187139847665704, "REMICADE": 3.113587102591687, "REVLIMID": 2.41295997739638, "RITUXIMAB": 4.54796354377316, "SIMEPREVIR": 2.618375889150215, "SKYRIZI": 1.0984789075300088, "SOMAVERT": 6.223032204913022, "TOBRAMYCIN": 4.071393377598039, "TRIUMEQ": 1.5771662217203826, "TRULICITY": 1.1359001486417006, "UNSPECIFIED": 1.740517290693485, "XOLAIR": 1.3144842082528916, "XYREM": 3.960839652326516, "ZEJULA": 3.091774643868139, "ZIAGEN": 3.369211735638504, "ZOSTAVAX": 1.2304238365607751, "null": 1.2563876318214162}
\ No newline at end of file
+{"COMIRNATY": 0.0525025820221976, "DOCETAXEL": 12.070621251638403, "DOXORUBICIN": 24.95755586541064, "HIZENTRA": 9.492918835545712, "ICLUSIG": 14.359773184809605, "JANUMET": 7.723254827986225, "KEYTRUDA": 5.386842558262338, "MEPOLIZUMAB": 5.632198337381257, "OPSUMIT": 8.045258836208513, "SIMPONI": 8.171946463991162, "STELARA": 3.017699492965854, "TRACLEER": 8.63911813377018, "TRELEGY": 8.959033493368791, "null": 1.4752620269426029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2556.json
index a5b76e51f3c..7fd041d5514 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2556.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2556.json
@@ -1 +1 @@
-{"ABACAVIR": 1.127807587705187, "ABASAGLAR": 2.380551933999816, "ABATACEPT": 2.138160620783381, "ABILIFY": 1.716227472613688, "ACCOFIL": 1.5724709858282837, "ACE": 1.4400819524728623, "ACETIC": 23.07043989973285, "ACTOS": 1.0675508443518809, "ACTRAPHANE": 1.3236055885593296, "ACTRAPID": 1.7464444288581966, "ADALIMUMAB": 2.319922583054951, "ADEFOVIR": 5.305748725842466, "ADVATE": 1.2670891747244868, "AERIUS": 1.0508875587891622, "AFATINIB": 1.5136161053315424, "AGOMELATINE": 3.684046978129013, "AIMOVIG": 2.314777476444408, "AJOVY": 1.2175530045308678, "ALECTINIB": 1.329834637503519, "ALEMTUZUMAB": 1.0391089203556156, "ALIGN": 2.548889891292984, "ALITRETINOIN": 3.599878987336271, "AMGEVITA": 4.702831812860649, "AMIKACIN": 3.25706331027822, "AMINOSALICYLIC": 1.7990173869007653, "AMIODARONE": 1.895792377577876, "ANAGRELIDE": 2.3448740544693165, "ANAKINRA": 5.274345155357734, "ANGIOTENSIN": 2.2254407225223947, "ANIDULAFUNGIN": 3.271138709902172, "ANTIDEPRESSANTS": 1.1795508927495169, 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"ZIEXTENZO": 5.025902228987543, "ZINPLAVA": 12.315350415126836, "ZONEGRAN": 1.2946551766351473, "ZONISAMIDE": 4.661092038611515, "ZYLLT": 3.1038392149901366, "null": 1.0057405840663287}
\ No newline at end of file
+{"REMICADE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2557.json
index ffc8b0216ff..76e211b9b51 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2557.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2557.json
@@ -1 +1 @@
-{"ABILIFY": 1.5625562972445737, "AERIUS": 2.2692270825389507, "AIMOVIG": 11.236269723556031, "ALEMTUZUMAB": 4.901909959900498, "AMIKACIN": 7.270823552460221, "ANAKINRA": 1.6765917043798877, "ARIPIPRAZOLE": 2.2124996322347488, "AZATHIOPRINE": 5.139986565293716, "BASILIXIMAB": 3.389537903435666, "BETMIGA": 4.61108210231941, "BEVACIZUMAB": 1.2212661698893097, "BLINATUMOMAB": 8.556100378777122, "BORTEZOMIB": 3.450920059997697, "BOSENTAN": 12.870863175247678, "BOTULINUM": 73.13723531916911, "BRINTELLIX": 1.2782949779937125, "BRIVARACETAM": 19.57758478632129, "BRIVIACT": 2.8059422310693307, "BUPIVACAINE": 2.6802205026410437, "BUSULFAN": 3.3457941497068537, "CANNABIDIOL": 4.169940626284627, "CASPOFUNGIN": 15.407117213745275, "CICLOSPORIN": 3.2554709414612835, "CIDOFOVIR": 66.20740585584294, "COSENTYX": 1.058473974766475, "CUBICIN": 9.444749775205455, "CYTARABINE": 1.2667677551999048, "DAPTOMYCIN": 22.347690034401577, "DEXAMETHASONE": 3.822502038601015, "DOXORUBICIN": 1.1322065741045164, "DULOXETINE": 1.1197939373047283, "ENOXAPARIN": 1.7060204500386826, "EPTACOG": 107.71962629765838, "ERENUMAB": 42.24218600054092, "ETANERCEPT": 8.014931198548112, "EYLEA": 1.0166481441432056, "FENTANYL": 1.753685051110038, "FILGRASTIM": 5.033851958869401, "GANCICLOVIR": 8.909125511865607, "HIZENTRA": 1.5928026704143632, "HUMAN": 107.69859318424828, "IMATINIB": 2.945392797713113, "INFLIXIMAB": 7.123284978221578, "JETREA": 12.579644328084632, "KEPPRA": 1.151396642770672, "LACOSAMIDE": 12.78595529019636, "LATUDA": 5.112215333049673, "LEFLUNOMIDE": 1.6370871832960234, "LEVETIRACETAM": 8.978242273934653, "LEVOFLOXACIN": 2.230452642797883, "LOPINAVIR": 10.756095552634152, "LURASIDONE": 40.96367447735837, "LYRICA": 3.078971119056433, "MELATONIN": 7.517565391667079, "MELPHALAN": 6.739094433697799, "METHOTREXATE": 2.650902310453519, "MIDAZOLAM": 2.849659646549826, "MYCOPHENOLATE": 1.9928434443111536, "NOT": 1.705321518121507, "NOVOSEVEN": 8.8789786987713, "OLANZAPINE": 1.3713679656498945, "POSACONAZOLE": 10.785472909912825, "PREGABALIN": 2.571178608871597, "PRIVIGEN": 5.125674555785447, "PROPRANOLOL": 7.692739741913924, "RAPAMUNE": 7.076652082996148, "REMICADE": 1.6726176144214997, "REVATIO": 1.556666238090216, "RIBAVIRIN": 1.282157071479071, "RITUXIMAB": 1.6088335833908112, "RUCONEST": 26.010284677450294, "SILDENAFIL": 2.036832974608958, "SIROLIMUS": 20.73629511858232, "SORAFENIB": 6.258355117317848, "STELARA": 1.37624950660824, "SUBOXONE": 3.074502447124595, "TOVIAZ": 1.56629215813757, "TRELEGY": 1.345985651226298, "TREMFYA": 1.034095913052533, "VANCOMYCIN": 179.0166295612363, "VFEND": 1.5820013765229672, "VIMPAT": 1.2510962992875645, "VISTIDE": 517.485225236522, "VORICONAZOLE": 12.449654114990109, "XELJANZ": 1.0148454867620438, "null": 1.6936947880825812}
\ No newline at end of file
+{"SPIKEVAX": 20.07808162052106, "VAXZEVRIA": 0.9370223506754836}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2558.json
index 9847d834bb3..5be0cc79687 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2558.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2558.json
@@ -1 +1 @@
-{"ABACAVIR": 1.0120141074739208, "ABASAGLAR": 1.1089679269301438, "ABILIFY": 2.6554956201486, "ABIRATERONE": 2.729721991634752, "ACE": 4.47462325957784, "ACLASTA": 2.6725078114305005, "ACTOS": 3.013931374908641, "ACTRAPID": 1.8767504900577416, "ADENURIC": 1.8853406864593047, "ADVAGRAF": 5.437171778323573, "AGOMELATINE": 4.938149239229934, "AKYNZEO": 5.481900324478512, "ALECENSA": 5.997742681229084, "ALL": 4.139369269879214, "ALLI": 4.003843311249107, "ALOXI": 1.9365070331439245, "AMIKACIN": 1.186273519018355, "ANTIBIOTICS": 2.8139688350245, "ANTIHYPERTENSIVES": 7.476289550973353, "APIXABAN": 1.013949668416532, "APROVEL": 1.513317713404542, "ARIPIPRAZOLE": 4.666860812128974, "ARIXTRA": 1.7524585932792114, "ARSENIC": 6.009614643584133, "ASPARAGINASE": 2.0734979320396865, "ATAZANAVIR": 20.133361695912857, "AXURA": 6.528500494655908, "AZILECT": 4.640938593139303, "BETA": 2.6753680037548326, "BETMIGA": 4.181480808333663, "BEXTRA": 2.094528464281381, "BIKTARVY": 1.70963073925933, 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\ No newline at end of file
+{"ALENDRONATE": 271.4723925592004, "APIXABAN": 18.356667918816942, "ARAVA": 0.2274665338259948, "BUDESONIDE": 50.12963326981951, "CICLOSPORIN": 1.738146294923939, "COMIRNATY": 0.0835627192981731, "ELIQUIS": 1.4702402620383936, "IRESSA": 4.587924595632598, "LEVOFLOXACIN": 1.5393584841477908, "MEPOLIZUMAB": 3.8667006130997432, "NUCALA": 65.08533851672354, "PEGASYS": 0.5474403305413073, "PRIALT": 105.50992778025244, "SPIKEVAX": 1.569236998141044, "TAMIFLU": 2.563153017956776, "XOLAIR": 1.062777139461759, "null": 0.8374129228804733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2559.json
index de71a5bfa2a..7e6e043be73 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2559.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2559.json
@@ -1 +1 @@
-{"ABACAVIR": 9.14315800120726, "ABATACEPT": 7.470687869213298, "ACE": 5.28008056330669, "ADALIMUMAB": 10.019198583773363, "ADCIRCA": 1.3134442470364356, "ADEMPAS": 2.084243444715785, "AFINITOR": 1.4461255265426904, "AGOMELATINE": 4.066895885148028, "AIMOVIG": 7.435817250022382, "AMBRISENTAN": 1.019602629252802, "AMGEVITA": 12.137867889216734, "AMIKACIN": 3.8688369079297513, "AMINOSALICYLIC": 1.124226666472154, "ANAGRELIDE": 9.591486456677035, "ANAKINRA": 10.596363906232725, "APREMILAST": 5.091118304412586, "APREPITANT": 7.682090277745229, "ARANESP": 7.090382748370273, "ARAVA": 14.61619281106328, "AVAMYS": 1.4156079573374376, "AZATHIOPRINE": 6.483061164382083, "BETMIGA": 1.3881496519210632, "BLINATUMOMAB": 1.8783166892073864, "BORTEZOMIB": 2.3158942234438435, "BOSULIF": 2.92648648392141, "BOSUTINIB": 35.6438050223111, "BOTULINUM": 23.207020329253915, "BRIVARACETAM": 3.0202577624951927, "BRIVIACT": 1.166667102017835, "BUPRENORPHINE": 1.123320494553082, "CABAZITAXEL": 1.2794319970921073, "CALCIUM": 13.948528772249734, "CAPECITABINE": 2.950623862903716, "CAPRELSA": 1.5817631888857564, "CARFILZOMIB": 1.334166877952126, "CELECOXIB": 4.258210336661126, "CICLOSPORIN": 2.4100663860778337, "CIMZIA": 5.01332174475362, "COMPRESSION": 22.426553224616264, "COSENTYX": 3.58841703098957, "DABRAFENIB": 1.700368798756435, "DASATINIB": 21.696017872901862, "DAXAS": 5.803328697589451, "DEXAMETHASONE": 1.0305092514784595, "DULOXETINE": 1.0672296697426114, "ENBREL": 12.402724176089857, "ENTRESTO": 1.7957043974075495, "ENTYVIO": 1.5045214563249485, "ERELZI": 6.4057197989351184, "ERENUMAB": 4.223786170108659, "ERTAPENEM": 4.326750183684414, "ESBRIET": 1.353717591663788, "ETANERCEPT": 3.074957687058699, "EVEROLIMUS": 3.5339743276471687, "EXFORGE": 1.1314849657262958, "EXJADE": 1.2576540488591827, "FASLODEX": 1.046188368009062, "FULVESTRANT": 1.751634720982122, "GLIVEC": 3.5773576897477954, "GLYCOPYRRONIUM": 9.480612739064918, "HUMAN": 1.7687754800945226, "HUMIRA": 5.6008762153665925, "IBRUTINIB": 1.4945776757618416, "IBUPROFEN": 1.1443905173943998, "ICLUSIG": 1.8877720662142323, "IKERVIS": 3.585108058030616, "IMATINIB": 10.132902389397584, "INFLIXIMAB": 2.402137436519203, "INVEGA": 1.167639927846839, "JAKAVI": 1.1079507979190784, "KIOVIG": 3.006177503677002, "KISQALI": 1.4114910282283384, "LACOSAMIDE": 1.7933849611721575, "LEFLUNOMIDE": 15.055739002464843, "LEVETIRACETAM": 1.9032193427189752, "LYNPARZA": 1.4116705267822305, "LYRICA": 1.1440150528906283, "METHOTREXATE": 1.8953971401390703, "MIMPARA": 13.614901194244338, "MYCOPHENOLATE": 1.502520132980524, "NILOTINIB": 12.934424257179831, "NOXAFIL": 1.272159918485786, "OCALIVA": 1.5607146322812613, "OFEV": 1.1606512672255485, "OLANZAPINE": 1.2490187729175026, "OLAPARIB": 1.130248366406707, "ORENCIA": 1.5609934143362008, "PANTOPRAZOLE": 1.138478166664063, "PAZOPANIB": 1.7867502262210944, "PEMETREXED": 1.7402143373184085, "PIRFENIDONE": 2.557877738884144, "PLEGRIDY": 2.039858693792359, "POSACONAZOLE": 1.3836620461411917, "PREGABALIN": 1.242342412522781, "PROPRANOLOL": 5.724773180912592, "QUTENZA": 1.4121140145619038, "REGORAFENIB": 3.873010062679604, "RIBOCICLIB": 1.1196398540600017, "RINVOQ": 1.4558676853645736, "RITUXIMAB": 2.0212168741163885, "RUBRACA": 2.3966967651935382, "RYBELSUS": 2.38673373486242, "SOMAVERT": 7.66977011149899, "SORAFENIB": 1.12890216219842, "SPRYCEL": 1.2954493332204569, "TASIGNA": 1.496431768342583, "THALIDOMIDE": 2.168788886952251, "TOBI": 7.478322078284209, "TOBRAMYCIN": 1.157056429889418, "VENCLYXTO": 5.303852887732111, "VENETOCLAX": 1.014764593792822, "VORICONAZOLE": 1.6595503408259895, "ZONISAMIDE": 5.296459878887359}
\ No newline at end of file
+{"SPIKEVAX": 46.13848117049877}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/256.json
index 2d66adec518..090770be764 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/256.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/256.json
@@ -1 +1 @@
-{"null": 2.2450342229325893}
\ No newline at end of file
+{"null": 2.044969251576027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2560.json
index ca0496e52b9..e7050d28351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2560.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2560.json
@@ -1 +1 @@
-{"null": 1.4694116034512523}
\ No newline at end of file
+{"COMIRNATY": 1.077274524831282, "TOZINAMERAN": 5.373582075129323, "VAXZEVRIA": 2.5179910148902613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2561.json
index 54d75969e13..cc90c9655d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2561.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2561.json
@@ -1 +1 @@
-{"HUMIRA": 39.534305112580185, "null": 1.0452345623587092}
\ No newline at end of file
+{"ABILIFY": 0.7810259945241692, "ACLIDINIUM": 1.955040360560544, "ACTOS": 0.4491120670264257, "ADALIMUMAB": 0.0109817438442506, "ADCIRCA": 0.6223641924915158, "ADEMPAS": 0.9819797210192688, "AERIUS": 0.4918724936615933, "AFINITOR": 0.5202157993561726, "AIMOVIG": 0.7852086633138587, "ALEMTUZUMAB": 1.0425793914524413, "ALIMTA": 0.4520408226215321, "ALISKIREN": 5.8874601522147785, "AMBRISENTAN": 0.5141522124935697, "ANORO": 1.5855670070070207, "ANTIHYPERTENSIVES": 5.198228119298911, "APIDRA": 0.1841910312360855, "APIXABAN": 1.567049413264613, "APROVEL": 0.3485720947766549, "ARANESP": 0.0790491020416271, "ARAVA": 0.0516072698028536, "ARIPIPRAZOLE": 0.2546812931747649, "ASPARAGINASE": 0.2112688857027709, "AUBAGIO": 0.3071299365154267, "AVAMYS": 1.6094072242219943, "AVANDAMET": 0.306821278777359, "AVANDIA": 0.6886901699744031, "AVASTIN": 0.3261337982336652, "AZATHIOPRINE": 0.1207063994946615, "BEDAQUILINE": 0.3320751988252756, "BENLYSTA": 0.904002187586185, "BETMIGA": 1.385209657188622, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2562.json
index cfe8c78500f..c38c6606302 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2562.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2562.json
@@ -1 +1 @@
-{"CICLOSPORIN": 2.120592527428202, "COAPROVEL": 12.404933993307871, "INFLIXIMAB": 17.692189066382436, "OLANZAPINE": 9.74909543278086, "VFEND": 13.726665512693025, "VORICONAZOLE": 30.833456662155744, "null": 3.955919432112195}
\ No newline at end of file
+{"COMIRNATY": 0.0617623311786537, "COSENTYX": 6.308259138711324, "CYTARABINE": 6.263185677137105, "ELIQUIS": 1.3206443200913307, "ESBRIET": 8.850699210365187, "FENTANYL": 3.473083565028991, "IBRANCE": 4.820755855398773, "OPSUMIT": 4.975122001288591, "SPIKEVAX": 0.207769079301684, "TOZINAMERAN": 0.6263756556604878, "VAXZEVRIA": 0.1019322336423503, "XELJANZ": 4.477748079362383, "null": 0.8956136950370026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2563.json
index 3f7bccc7055..be1b527c15e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2563.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2563.json
@@ -1 +1 @@
-{"ABACAVIR": 2.100719136037982, "ARIPIPRAZOLE": 16.41116639755399, "CICLOSPORIN": 2.767000487786216, "CRESEMBA": 67.31762036114814, "ENTYVIO": 4.904884013450886, "INSULIN": 4.4286373594416375, "KEPPRA": 2.687856974715756, "LEVETIRACETAM": 4.758191441114706, "NOXAFIL": 65.37934506990794, "OLANZAPINE": 1.889264823302865, "POSACONAZOLE": 86.68917342704319, "RAPAMUNE": 15.167214969841057, "SOLIRIS": 3.1295819537836214, "STELARA": 20.096254800846705, "TACROLIMUS": 20.324218023469687, "VFEND": 24.51036620670869, "VORICONAZOLE": 104.16445050301728, "null": 1.5150638139902346}
\ No newline at end of file
+{"ABACAVIR": 0.2162580504273545, "ABATACEPT": 1.1216607608953688, "ABILIFY": 0.4659259515762546, "ABRAXANE": 0.4572429270725944, "ACCOFIL": 3.674712311667832, "ACLASTA": 0.9732586347659824, "ACTOS": 1.5343559754579892, "ADALIMUMAB": 1.2847890709522256, "ADCIRCA": 1.3300536867440755, "ADEMPAS": 1.2168228509870644, "ADENURIC": 0.4834105049772556, "AERIUS": 0.4957402447482996, "AFINITOR": 0.572740449493601, "AIMOVIG": 0.6696010599601189, "AJOVY": 2.016973804504882, "ALDARA": 0.3068111620044042, "ALEMTUZUMAB": 0.4563124863207107, "ALIMTA": 0.5150092204707418, "ALISKIREN": 0.2351008524321361, "AMBRISENTAN": 1.5458893668599147, "AMINOSALICYLIC": 0.8945153190506763, "ANAKINRA": 0.2476749554526414, "ANGIOX": 2.0049694070971675, "ANORO": 0.6929905810803121, "ANTIBIOTICS": 0.7233478196998401, "APIDRA": 0.2594476842977231, "APIXABAN": 1.777917855445062, "APREMILAST": 0.1559214462964271, "APREPITANT": 0.956367520112554, "APROVEL": 0.7388685444106156, "ARANESP": 0.3564625219783905, "ARAVA": 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1.0638324958486145, "ZOSTAVAX": 0.6700131159310216, "ZYPREXA": 0.7004607761870915, "null": 0.7122333452256324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2564.json
index 28879f1ff1e..d9314f9d628 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2564.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2564.json
@@ -1 +1 @@
-{"CRIXIVAN": 124.1234648259444, "KALETRA": 22.53118209201996, "null": 1.7153464163250411}
\ No newline at end of file
+{"null": 0.8964449791949424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2565.json
index 58b4b89f6fc..d0985d1beca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2565.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2565.json
@@ -1 +1 @@
-{"AFINITOR": 1.7250655727602713, "CABOTEGRAVIR": 36.412762699084695, "CASPOFUNGIN": 12.284408923300033, "CELLCEPT": 5.639861650525777, "CETRORELIX": 328.1129832369037, "CICLOSPORIN": 6.808993477372205, "DEXAMETHASONE": 1.1272410075668895, "EFAVIRENZ": 4.904298497000596, "ENTYVIO": 17.02778537103065, "FYCOMPA": 11.044919091057174, "HEMLIBRA": 11.93836889004657, "HUMIRA": 9.181185550406468, "INFLIXIMAB": 24.54791871576932, "KALETRA": 2.4322984104551035, "KEPPRA": 4.16025677473194, "LACOSAMIDE": 8.494667313459026, "LEVETIRACETAM": 7.498197467674996, "LUMACAFTOR": 575.3483451786454, "NORVIR": 5.582330660875571, "NOXAFIL": 27.332020931715466, "OLANZAPINE": 1.095717056165472, "POSACONAZOLE": 18.90997515650169, "RAPAMUNE": 15.113397122277602, "REKAMBYS": 57.38686858310708, "REMICADE": 7.737995471831603, "SIMPONI": 1.0981417376893614, "SOLIRIS": 1.6518818686775012, "STELARA": 11.686140961089244, "TACROLIMUS": 20.65286278363047, "VFEND": 14.051209239510868, "VORICONAZOLE": 26.564999521990018, "XENICAL": 155.18513374722136, "ZYPADHERA": 4.112976623075581, "null": 2.138355254123373}
\ No newline at end of file
+{"null": 1.3488381612584937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2566.json
index 5897c4ccfa2..cf4e7f55535 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2566.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2566.json
@@ -1 +1 @@
-{"CELLCEPT": 12.600813457827252, "CICLOSPORIN": 5.701800007027876, "SUBOXONE": 12.910016547344798, "null": 3.2520925913554986}
\ No newline at end of file
+{"CYTARABINE": 45.65588686346895, "null": 0.6009207402278406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2567.json
index 37f56ba2b3a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2567.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2567.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 18.927815436184662, "ATAZANAVIR": 6.197060041964054, "BRIVIACT": 5.952001614153716, "BUPRENORPHINE": 1.4950236937514998, "CANCIDAS": 4.169222468464975, "CANNABIDIOL": 22.37793394794624, "CARBIDOPA": 4.113538364510226, "CELECOXIB": 2.765427457674132, "CELLCEPT": 3.395631857025814, "CICLOSPORIN": 7.454684392665531, "CRESEMBA": 7.179809644930304, "DULOXETINE": 2.944671805267814, "ENVARSUS": 98.44054676239128, "ESOMEPRAZOLE": 3.4827426274030016, "EVEROLIMUS": 2.9005944344684376, "FENTANYL": 2.729705811669638, "GLIVEC": 2.895876863807616, "HEMLIBRA": 4.259139563805238, "HYDROCORTISONE": 2.15012736949981, "IBUPROFEN": 1.6039797543977832, "INTELENCE": 6.767579741795777, "KAFTRIO": 1.2743852802781244, "KALETRA": 7.890271109023095, "KEPPRA": 2.210789427682471, "LEVETIRACETAM": 2.8144704735512738, "LOPINAVIR": 24.697288336057355, "LYRICA": 1.7407988109557058, "METHOTREXATE": 1.2354714692625288, "MICARDIS": 1.431541754073938, "MIDAZOLAM": 2.180560657222442, "MYCOPHENOLATE": 3.01768961820426, "NORVIR": 2.8310270506297863, "NOT": 1.439707932888982, "NOXAFIL": 10.15602281033183, "OLANZAPINE": 4.030026095105472, "OXYBUTYNIN": 3.111590089963627, "POSACONAZOLE": 10.8114680578307, "PREGABALIN": 4.928880430277475, "RAPAMUNE": 13.023604657935833, "RISPERIDONE": 2.6775494459026072, "RITONAVIR": 12.3942102715817, "SILDENAFIL": 1.5809190599854248, "SODIUM": 21.253946300848245, "TACROLIMUS": 28.988626951777054, "TELMISARTAN": 2.8350645496234783, "TOBRAMYCIN": 19.419871543939724, "VFEND": 21.36679761681834, "VIMPAT": 1.5686214670222132, "VORICONAZOLE": 19.49937869865424, "VORTIOXETINE": 12.777375292865074, "ZYPADHERA": 4.2712946673072505, "ZYPREXA": 2.7521604163721265, "null": 3.527409414526013}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2568.json
index c57232a4ba2..584cdc0811b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2568.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2568.json
@@ -1 +1 @@
-{"null": 1.0073536249268118}
\ No newline at end of file
+{"BRILIQUE": 44.143306746537945, "null": 3.2552810652213093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2569.json
index c5ec17ed6e9..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2569.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2569.json
@@ -1 +1 @@
-{"null": 3.68835493648122}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/257.json
index f6982679317..3a27b3b8d48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/257.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/257.json
@@ -1 +1 @@
-{"ATRIPLA": 2.5058549132211643, "CHAMPIX": 13.309913500993988, "CYMBALTA": 4.040936681818285, "FENTANYL": 6.628425222830841, "null": 2.004823590841542}
\ No newline at end of file
+{"MIMPARA": 142.36102134351103, "null": 1.619073581651186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2570.json
index e24b71b7900..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2570.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2570.json
@@ -1 +1 @@
-{"LEMTRADA": 46.96732077351384, "null": 2.499286384766875}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2571.json
index 322f1122dc6..63b2035173b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2571.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2571.json
@@ -1 +1 @@
-{"AERIUS": 3.5391214777247915, "AMIKACIN": 19.39997331861376, "ANAKINRA": 1.1779885316981802, "APROVEL": 1.205386794827565, "ARIXTRA": 3.772875855038649, "AZTREONAM": 8.919600813126442, "BEDAQUILINE": 1.0403329229502578, "BORTEZOMIB": 2.72253755243984, "BRIDION": 2.77440204496636, "BRILIQUE": 1.3379690488479612, "CANCIDAS": 14.97689525110187, "CASPOFUNGIN": 3.906726929173579, "CELECOXIB": 4.862911813198087, "COBIMETINIB": 45.40716088385664, "COTELLIC": 34.60012310026578, "CUBICIN": 10.73023131098096, "DABRAFENIB": 3.6043146061928, "DAPTOMYCIN": 23.59813482989423, "DELAMANID": 6.907986199416337, "DESLORATADINE": 2.3658860560926374, "EMTRICITABINE": 4.322383048592998, "ERLEADA": 9.465834980422398, "ERTAPENEM": 17.272108767290977, "ESOMEPRAZOLE": 5.357720300893071, "FEBUXOSTAT": 5.735128153546387, "GANCICLOVIR": 4.233421784225564, "HUMAN": 1.034531809482132, "IBUPROFEN": 1.8166703515595712, "INCIVO": 13.482435657217954, "INTELENCE": 7.953675493072498, "INVANZ": 13.5146753479387, "IPILIMUMAB": 1.899391019233368, "IRBESARTAN": 2.2737388779374763, "ISENTRESS": 17.624554934903053, "KEPPRA": 5.798227201115124, "KIVEXA": 4.263325949771924, "LACOSAMIDE": 2.915482333301618, "LEVETIRACETAM": 13.917262267872736, "LEVOFLOXACIN": 4.455676240844641, "LYRICA": 1.5968036453642305, "MICARDIS": 1.4471701399540788, "MIDAZOLAM": 1.5233011989763594, "NEVIRAPINE": 9.589111702593245, "NORVIR": 5.079185470480707, "NOT": 1.2468551254796736, "OCTREOTIDE": 7.935000261638885, "OLANZAPINE": 1.7988685517236047, "OPDIVO": 1.0363882122318957, "OSSEOR": 36.90327943788094, "PANTOPRAZOLE": 6.759418479390445, "PEGASYS": 1.2676449270042487, "PEGINTERFERON": 11.392028513729947, "PRADAXA": 1.9092392802615117, "PROTELOS": 27.718946716368777, "REVLIMID": 4.843724283090128, "RIBAVIRIN": 2.9907391295144867, "SPIRONOLACTONE": 6.40340977636457, "SUFENTANIL": 1.512506683610502, "TAMIFLU": 1.2778819113739175, "TELMISARTAN": 2.4107711183112275, "TEMODAL": 1.978038957954501, "TEMOZOLOMIDE": 4.738067750484578, "THALIDOMIDE": 5.232508679075661, "VFEND": 1.6057391362888591, "VIMPAT": 3.873882122695241, "VIRAMUNE": 4.317680861849677, "VORICONAZOLE": 1.609439684552792, "ZELBORAF": 6.590325407977982, "ZONISAMIDE": 7.466355660520493, "null": 3.893697904017204}
\ No newline at end of file
+{"SIMPONI": 24.422793006227327, "STELARA": 40.77353420047819, "null": 0.6468042779807913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2572.json
index cf0ba695fa8..b501e8acab5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2572.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2572.json
@@ -1 +1 @@
-{"null": 2.325722557999482}
\ No newline at end of file
+{"ARIPIPRAZOLE": 222.1279623487024, "null": 1.2060800367094704}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2573.json
index c0b6496dfb1..28fa3da4df2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2573.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2573.json
@@ -1 +1 @@
-{"ABACAVIR": 8.986599769085734, "ADEFOVIR": 162.91823534825764, "AFATINIB": 46.1857950846204, "ALECTINIB": 24.285949596603377, "ALEMTUZUMAB": 4.3984065013946, "AMIKACIN": 31.621807338038334, "AMINOSALICYLIC": 6.877050539761385, "AMPRENAVIR": 27.7725328581426, "ANIDULAFUNGIN": 32.48423929122619, "ARIPIPRAZOLE": 3.706426213916204, "ATAZANAVIR": 14.086224655416688, "AVAPRITINIB": 85.13210303001547, "AZACITIDINE": 2.460042616203085, "AZATHIOPRINE": 1.2521987891830555, "AZTREONAM": 14.390025647687796, "BARACLUDE": 56.71241890902205, "BASILIXIMAB": 14.521440558411316, "BEDAQUILINE": 4.198202117026216, "BEVACIZUMAB": 4.207966585288656, "BIKTARVY": 13.496253773232944, "BORTEZOMIB": 4.24769533979567, "BOSULIF": 2.127813673801134, "BOSUTINIB": 55.23884140868691, "BOTULINUM": 2.5934303984837475, "BRIVARACETAM": 9.846605225472588, "BUSULFAN": 2.1420656482557527, "CANCIDAS": 12.67587317565221, "CANNABIDIOL": 2.517949753545401, "CAPECITABINE": 1.7686122127382644, "CARIPRAZINE": 20.66326783732023, "CASPOFUNGIN": 29.75388852693252, "CEFEPIME": 42.43951397031212, "CEFTAZIDIME": 49.459272413470735, "CELSENTRI": 10.89045383743329, "CICLOSPORIN": 4.202769455309068, "CIDOFOVIR": 66.19412812334754, "CLOFARABINE": 5.220164781447125, "CLOPIDOGREL": 3.827997398253055, "COMBIVIR": 1.2133949234344168, "CORTICOSTEROID": 18.85088162336985, "CRIXIVAN": 10.394303020324488, "CRIZOTINIB": 25.86674604070391, "CUBICIN": 11.405141995636962, "CYTARABINE": 3.6682188262294138, "DABRAFENIB": 8.563251101083688, "DACLATASVIR": 3.4354189144129426, "DAKLINZA": 3.862540736610312, "DAPTOMYCIN": 16.96060549943664, "DARUNAVIR": 18.23457458881037, "DARZALEX": 1.0766153467076849, "DASATINIB": 55.84951292110906, "DELAMANID": 3.2004237402802573, "DESCOVY": 9.390049238320705, "DEXAMETHASONE": 2.8804475710244724, "DOCETAXEL": 2.057671630307007, "DOLUTEGRAVIR": 16.338730060176587, "DOXORUBICIN": 2.046394853986681, "DULOXETINE": 1.797328426764058, "EDURANT": 8.947842229864875, "EFAVIRENZ": 18.75058872077989, "EMTRICITABINE": 28.68399807816939, "EMTRIVA": 19.236133938849942, "ENBREL": 1.0935795939904518, "ENTECAVIR": 109.3203281592032, "EPIVIR": 3.809719538367165, "ERLOTINIB": 127.23124849934706, "ERTAPENEM": 14.928830600133995, "ESKETAMINE": 236.10679660195305, "EVEROLIMUS": 5.273792086447853, "FIDAXOMICIN": 16.348234021143536, "FULVESTRANT": 1.2437652911621524, "GANCICLOVIR": 64.03121628065877, "GEFITINIB": 149.64231670061238, "GENVOYA": 19.78828288861536, "GLIVEC": 11.69634249410196, "HARVONI": 4.306003531993655, "HEPSERA": 48.16925443337597, "HUMAN": 5.150330505175726, "IBRUTINIB": 8.485543119963147, "ICLUSIG": 2.6884976361881665, "IMATINIB": 45.99026976991454, "INFLIXIMAB": 1.7532363172544343, "INTELENCE": 5.547178033788962, "IRESSA": 70.67642715786374, "IRINOTECAN": 1.2067468910966752, "ISENTRESS": 5.38515577992749, "LACOSAMIDE": 23.80958056751449, "LAMIVUDINE": 10.233656324555149, "LEVETIRACETAM": 15.653016394293587, "LEVOFLOXACIN": 5.016391771274482, "LOPINAVIR": 4.345861685581512, "LOXAPINE": 16.684796681170937, "LYNPARZA": 1.0570787529292085, "MEKINIST": 2.039196824706073, "METHOTREXATE": 2.2997523685923595, "MICAFUNGIN": 9.014122277824814, "MIDAZOLAM": 1.8543331478717089, "MYCOPHENOLATE": 3.0396911705658147, "NEVIRAPINE": 6.520830090898225, "NILOTINIB": 23.846169402817285, "NORVIR": 1.5774648646492848, "NOT": 1.6775706641906132, "OLANZAPINE": 1.3812797800792405, "OLAPARIB": 8.319354230066157, "OLYSIO": 1.1915085164751782, "OSELTAMIVIR": 10.3997089083515, "OSIMERTINIB": 104.07428461205674, "PACLITAXEL": 1.4191154192941278, "PANITUMUMAB": 5.462208552802176, "PEMBROLIZUMAB": 1.4741734220354226, "PLAVIX": 1.5480518556866134, "POSACONAZOLE": 9.194598382781573, "REYATAZ": 10.274192212131634, "RIBAVIRIN": 1.9556069135469152, "RITUXIMAB": 1.5929990632354207, "SOVALDI": 1.3193407632459289, "SPRYCEL": 2.3768187423880542, "STRIBILD": 2.2244384333546305, "TACROLIMUS": 1.7422318623715174, "TAGRISSO": 4.47367629226466, "TAMIFLU": 1.4868081561797075, "TASIGNA": 2.747641535817559, "TECOVIRIMAT": 254.29199408251824, "TELITHROMYCIN": 148.29231174476035, "TEMOZOLOMIDE": 6.000159797207004, "TENOFOVIR": 12.66793728472928, "TIGECYCLINE": 27.81282443104805, "TIVICAY": 3.075588478323166, "TOBRAMYCIN": 9.636538525884005, "VEMLIDY": 6.855741903061904, "VIRAMUNE": 6.119840934414189, "VIREAD": 4.757009853657179, "VORICONAZOLE": 16.994754019021116}
\ No newline at end of file
+{"HEXYON": 3416.1109959636137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2574.json
index 98660d630c4..402f34a36fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2574.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2574.json
@@ -1 +1 @@
-{"BIKTARVY": 183.54765795258527}
\ No newline at end of file
+{"SUBOXONE": 116.89590583265442, "null": 1.603923508799126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2575.json
index 4cbae976001..ade1017925b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2575.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2575.json
@@ -1 +1 @@
-{"null": 3.2034584186415667}
\ No newline at end of file
+{"INTELENCE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2576.json
index 5170dec3c24..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2576.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2576.json
@@ -1 +1 @@
-{"SUBOXONE": 237.64494611689344}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2577.json
index bf784bece88..97a0d9828dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2577.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2577.json
@@ -1 +1 @@
-{"BENZODIAZEPINE": 135.42320396809225, "BENZODIAZEPINES": 462.15194297836354, "BUPRENORPHINE": 67.45730433557031, "CYMBALTA": 2.321065366623792, "FENTANYL": 3.08417551425806, "GLUCAGON": 55.20627207166592, "IBUPROFEN": 4.328366632475922, "KEPPRA": 4.244443078178049, "OLANZAPINE": 3.654101336807519, "OPIOIDS": 169.0674731848615, "SUBOXONE": 31.266184512179965, "XYREM": 26.8361402461562, "null": 1.9874705005892332}
\ No newline at end of file
+{"EXVIERA": 502.17815484810274, "NEXAVAR": 30.98701604734112, "OCALIVA": 872.0945336558773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2578.json
index 38d22c76471..14806133b87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2578.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2578.json
@@ -1 +1 @@
-{"ABATACEPT": 3.0548685235044983, "ADALIMUMAB": 8.83841717855985, "ANAKINRA": 41.92979281788055, "ARANESP": 9.059478472726886, "ETANERCEPT": 118.6208654256426, "HUMIRA": 9.931142126017075, "KOGENATE": 316.4478466455078, "NEORECORMON": 367.845356566029, "STELARA": 3.96007700881108, "null": 1.6913073680207311}
\ No newline at end of file
+{"null": 1.905017702804813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2579.json
index ddf350f1752..f3fd9059cce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2579.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2579.json
@@ -1 +1 @@
-{"ARANESP": 136.5510687603988, "CELLCEPT": 15.100755960136024, "EPOETIN": 143.78375634679756, "PEGASYS": 2.7744894909161397, "null": 2.538344019046156}
\ No newline at end of file
+{"COMIRNATY": 3.632306489687204, "MODERNA": 6.294648697721823, "SPIKEVAX": 1.5946985630911164, "TOZINAMERAN": 2.7959002409491296, "VAXZEVRIA": 1.6822827172490842, "null": 0.2127259840600114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/258.json
index 59cb7506875..7ce4aded616 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/258.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/258.json
@@ -1 +1 @@
-{"ACTRAPID": 1.979412821377983, "ADENURIC": 5.867633198958331, "ADVAGRAF": 6.932698091959746, "AERIUS": 1.8791557766017983, "ALIMTA": 1.7062092893896377, "AMIKACIN": 1.3793893226995522, "APROVEL": 2.004508894410474, "ARIPIPRAZOLE": 1.9097933487047092, "ASPARAGINASE": 1.4116944706917915, "AZACITIDINE": 3.956415070085957, "BORTEZOMIB": 1.8027371456653367, "BUSULFAN": 1.142180027007329, "CAELYX": 1.5547548518482766, "CANCIDAS": 5.870420614198936, "CARMUSTINE": 1.6211942845451417, "CASPOFUNGIN": 1.4025245603625616, "CELLCEPT": 11.07584577854706, "CIRCADIN": 4.245743534894539, "CLADRIBINE": 2.2373629814570224, "CLOPIDOGREL": 1.02568296561457, "COAPROVEL": 2.2035560940444507, "COMBIVIR": 1.063593523471496, "CUBICIN": 1.797662580027471, "CYTARABINE": 2.4646868362278846, "DEXAMETHASONE": 1.4897780338062434, "DIFICLIR": 7.199926436183636, "DOCETAXEL": 10.306756079425655, "DOXORUBICIN": 8.878035913894303, "EMEND": 1.2758423381695887, "ERLEADA": 2.359840747130188, "ESOMEPRAZOLE": 2.2987826791316937, "FEBUXOSTAT": 1.688375664029723, "FILGRASTIM": 6.656439416068348, "GANCICLOVIR": 4.13365249352052, "GAZYVARO": 4.248517937858285, "HERCEPTIN": 1.2741535546979186, "HYCAMTIN": 2.2458824067425622, "HYDROCORTISONE": 1.0727064791529215, "IBUPROFEN": 3.023433015496555, "IMBRUVICA": 1.5766561539647188, "INTRONA": 1.0688917036705678, "IRBESARTAN": 1.0184123656810455, "IRINOTECAN": 1.002088220442272, "JEVTANA": 1.3774970841878869, "KEPPRA": 3.045904103465473, "KESIMPTA": 1.252132772681713, "KINERET": 15.808854883498803, "KYMRIAH": 1.1138862729744792, "LEVETIRACETAM": 1.713585657006084, "LEVOFLOXACIN": 1.2703981172603689, "LYRICA": 1.2275769681961288, "MABCAMPATH": 5.171829540164675, "MABTHERA": 21.35592202430412, "MELPHALAN": 1.8297500064163823, "MERCAPTOPURINE": 4.254285438140775, "METHOTREXATE": 2.0361812506376182, "NORVIR": 1.724777550320212, "OBINUTUZUMAB": 1.8907737336122816, "OLANZAPINE": 2.334557891442586, "PACLITAXEL": 5.400041867307678, "PANTOPRAZOLE": 2.912063221209612, "PEGASPARGASE": 13.683229995519577, "PEGFILGRASTIM": 2.809958748333007, "PEMBROLIZUMAB": 1.1418035867917276, "PEMETREXED": 1.4471252957970564, "PLAVIX": 4.914840252785733, "PREGABALIN": 1.0004646823020185, "PROPRANOLOL": 1.7309411673012598, "RILUTEK": 7.717355657915041, "RITUXIMAB": 5.450813582679331, "RIXATHON": 10.16501930291214, "ROACTEMRA": 1.4380695657246976, "TAMIFLU": 1.3038962950811628, "TAXOTERE": 32.64999280948443, "TEMODAL": 6.893313513070406, "TEMOZOLOMIDE": 1.47496800116783, "THALIDOMIDE": 1.2962426939478786, "VENETOCLAX": 3.4474401026453334, "VFEND": 2.820135410799613, "VIMPAT": 2.426673470568219, "VORICONAZOLE": 1.3015315512965766, "XARELTO": 1.29815629587975, "XELODA": 1.9832377627022972, "ZYPREXA": 1.4622845144148342, "null": 4.927088453389699}
\ No newline at end of file
+{"null": 0.7507753524980778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2580.json
index 8b31241809e..b74c72a5538 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2580.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2580.json
@@ -1 +1 @@
-{"ADALIMUMAB": 11.13210291171388, "AMINOSALICYLIC": 10.871088511389091, "ANAKINRA": 33.578332789708206, "ARANESP": 10.780699717297322, "AZATHIOPRINE": 15.009365499079523, "CIMZIA": 5.190419002760764, "EMICIZUMAB": 540.4426166802308, "ENTYVIO": 47.27323205432713, "HEMLIBRA": 158.56430117260803, "HUMIRA": 19.19326179103208, "INFLIXIMAB": 50.01696414162971, "NEULASTA": 18.032124041146933}
\ No newline at end of file
+{"ABACAVIR": 0.0342314956113765, "ABILIFY": 0.0178415309290047, "ABRAXANE": 0.1009604621517184, "ACLIDINIUM": 0.2189904657307268, "ACTOS": 0.070239230232996, "ACTRAPID": 0.1373351260842021, "ADALIMUMAB": 0.0281071328449966, "ADCIRCA": 0.1467558061135368, "ADEMPAS": 0.0727590433953664, "ADVATE": 0.1455469395621785, "AERIUS": 0.0860549005474256, "AFINITOR": 0.0998658758006428, "AIMOVIG": 0.0944129677695672, "ALDARA": 0.322543692361657, "ALEMTUZUMAB": 0.0983196532215197, "ALIMTA": 0.0379870880239702, "AMIKACIN": 0.0773982644916596, "APIDRA": 0.0430059637397292, "APIXABAN": 0.0493480924619192, "APROVEL": 0.0448045359792563, "ARANESP": 0.0363681681666085, "ARAVA": 0.055701390708331, "ARSENIC": 0.9268715534051336, "ARZERRA": 0.3166063723235993, "ASPARAGINASE": 0.0820628413633958, "ATAZANAVIR": 0.0290667480575052, "ATRIPLA": 0.0015071163100366, "AUBAGIO": 0.0761985778010986, "AVAMYS": 0.0144124774616473, "AVANDIA": 0.0104583317320113, "AVASTIN": 0.1642751871493017, "AVELUMAB": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2581.json
index 30cac8985b4..f97393ab048 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2581.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2581.json
@@ -1 +1 @@
-{"null": 9.92549416813464}
\ No newline at end of file
+{"CICLOSPORIN": 42.96167304410493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2582.json
index 984b1b98e6c..d655a9ceb93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2582.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2582.json
@@ -1 +1 @@
-{"ARANESP": 712.9981526898817, "DARBEPOETIN": 1909.175898647532}
\ No newline at end of file
+{"ZAVESCA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2583.json
index 176864151c1..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2583.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2583.json
@@ -1 +1 @@
-{"BUVIDAL": 1356.4727640371566, "HEMANGIOL": 2301.0846467385527, "SAXENDA": 38.86317134855557, "VICTOZA": 50.32299888265407}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2584.json
index db9a76c3a3e..3dece68169b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2584.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2584.json
@@ -1 +1 @@
-{"ABATACEPT": 5.714828708205755, "ADALIMUMAB": 24.904701784995314, "ARAVA": 2.11645187883455, "AZATHIOPRINE": 5.221377074685469, "BARACLUDE": 54.379619228667366, "BUPRENORPHINE": 13.567579325375942, "CLOPIDOGREL": 1.1481639623925184, "DULOXETINE": 5.531453217961254, "ENBREL": 3.602282378117938, "FENTANYL": 34.39693456231795, "HEPSERA": 15.61960145484399, "IRESSA": 16.780137723758106, "LYRICA": 2.2256111908488414, "null": 1.055117633929512}
\ No newline at end of file
+{"COMIRNATY": 0.3887102753095121, "null": 0.9343516303691768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2585.json
index 43ef7cfefa4..859d325a465 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2585.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2585.json
@@ -1 +1 @@
-{"ABATACEPT": 10.428915828017496, "ABILIFY": 1.945664536886652, "ADALIMUMAB": 25.17719076380436, "AMINOSALICYLIC": 8.440006691825143, "APREMILAST": 27.00138262471977, "ARAVA": 22.93940708484903, "CIMZIA": 1.0729490299418587, "COSENTYX": 1.4811089673106084, "DEXAMETHASONE": 1.672464313617004, "ENBREL": 16.58228362061501}
\ No newline at end of file
+{"null": 2.688163851193987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2586.json
index 96c5c599ba3..32f7c3ce8f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2586.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2586.json
@@ -1 +1 @@
-{"FENTANYL": 23.710588322222087, "null": 3.078200487967968}
\ No newline at end of file
+{"BUSULFAN": 93.9472273648396, "CYTARABINE": 35.535503929416336, "null": 0.2113861779821472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2587.json
index d99f03ce9c4..472a3d05d21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2587.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2587.json
@@ -1 +1 @@
-{"ANAKINRA": 4.46261842793169, "BUPRENORPHINE": 37.26606121857372, "ENBREL": 28.38479183045444, "FENTANYL": 12.25285214192226, "LYRICA": 4.70881465251169, "OLANZAPINE": 1.0118260249088056, "PREGABALIN": 22.54446343863576, "SUBOXONE": 1.507899327356864, "ZYPREXA": 2.339296383948818, "null": 4.840316325346827}
\ No newline at end of file
+{"VFEND": 240.6367787300532, "VIAGRA": 193.30419561825585, "VORICONAZOLE": 127.34994018849072, "null": 0.3370746845472986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2588.json
index 81c244d73cb..033c32c6535 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2588.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2588.json
@@ -1 +1 @@
-{"FYCOMPA": 30.46257916292862, "KEPPRA": 7.364300211132145, "LACOSAMIDE": 17.106628121265516, "LEVETIRACETAM": 8.602827307342709, "SUBOXONE": 5.4319396963362045, "null": 7.484072770518285}
\ No newline at end of file
+{"null": 11.1380970657273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2589.json
index d52ef31c3ae..925b9e5cb37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2589.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2589.json
@@ -1 +1 @@
-{"COVID19": 1.2960444219681264, "CYMBALTA": 12.384844739571442, "null": 3.2927905000069786}
\ No newline at end of file
+{"DELSTRIGO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/259.json
index 3f930c0c7d3..38da4e3fe0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/259.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/259.json
@@ -1 +1 @@
-{"FENTANYL": 25.09130461032556, "null": 3.175990198234768}
\ No newline at end of file
+{"COMIRNATY": 4.328542254621087, "ESMYA": 184.05825029246887, "SPIKEVAX": 0.8283348605595109, "VAXZEVRIA": 0.2944533837799204, "null": 0.4824124056291086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2590.json
index 00b903af8bf..aae75b49f31 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2590.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2590.json
@@ -1 +1 @@
-{"null": 3.601654780680706}
\ No newline at end of file
+{"ABILIFY": 1.0460981586171596, "AFINITOR": 0.3912470396862471, "AIMOVIG": 0.5084826186587221, "ANORO": 5.440132286604418, "ARAVA": 0.0825439190853855, "AVAMYS": 2.4025706830846496, "BRILIQUE": 2.012907951685276, "BRINTELLIX": 0.6311000678704604, "BUDESONIDE": 0.3173286597390017, "BUPRENORPHINE": 9.077813496068876, "CELLCEPT": 0.5545017255631298, "CLOPIDOGREL": 0.4853425388975028, "COMIRNATY": 0.1265990067222262, "COMTAN": 6.046088126811237, "COSENTYX": 0.5117535611096552, "CYMBALTA": 0.2035616252682259, "DEXAMETHASONE": 0.4820469510535043, "ELIQUIS": 0.636045646728806, "ENBREL": 0.8884718611340391, "ENTRESTO": 0.7333494914518374, "ESBRIET": 1.2058020091912682, "EXFORGE": 2.09083577988157, "FASENRA": 1.0559800840399118, "FIRDAPSE": 2.9498612247891223, "GARDASIL": 0.6682413321967909, "GLYCOPYRRONIUM": 12.690589165002294, "IBRANCE": 2.029865143913375, "INCRUSE": 16.182369495033704, "IRBESARTAN": 2.3272563654825715, "JANUMET": 1.5352735222106226, "KEPPRA": 0.6609304126309454, "KEYTRUDA": 0.2017363742819807, "LANTUS": 0.5964877876774523, "MEPOLIZUMAB": 5.190606981218683, "MICARDIS": 1.1078923095577615, "NUCALA": 2.776255233860846, "OLANZAPINE": 0.9688204954679376, "OMALIZUMAB": 3.2891615325911583, "OPSUMIT": 0.9723091988617726, "OXYBUTYNIN": 4.180684478378654, "PANTOPRAZOLE": 2.0038757668069174, "PEGASYS": 0.2182454116992019, "PLAVIX": 0.2983973888584479, "PREVENAR": 3.4351448641797337, "RELVAR": 2.2579712221713835, "ROTATEQ": 5.406119733405012, "SOLIRIS": 1.027242932624778, "SPIKEVAX": 0.1659918532787709, "SPINRAZA": 6.074218162951523, "STALEVO": 5.741959648652567, "SUBOXONE": 0.447804362273742, "SUTENT": 0.7538527552039146, "SYNAGIS": 2.8745433807955103, "TOVIAZ": 1.3384815232466512, "TOZINAMERAN": 0.6898860965462981, "TRELEGY": 26.49731970595423, "VAXZEVRIA": 0.0831786862522741, "VIAGRA": 0.93071171866662, "XELJANZ": 1.2869461728221927, "XOLAIR": 2.697133503589303, "XTANDI": 3.0075903289379786, "ZYPREXA": 0.4481758760432707, "null": 3.124189549388848}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2591.json
index 2d7c4f2ef2f..98c5180c6f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2591.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2591.json
@@ -1 +1 @@
-{"ACLASTA": 5.578997902856047, "ARIPIPRAZOLE": 1.1407081061425224, "ARSENIC": 20.446490172271535, "BENZODIAZEPINE": 9.57965703394802, "BRINTELLIX": 1.0136149491762596, "BUMETANIDE": 5.3303540269639145, "BUPIVACAINE": 15.95806483657304, "BUPRENORPHINE": 27.842789035770043, "BUVIDAL": 9.062927083250036, "CARBIDOPA": 2.3575503934112083, "CHAMPIX": 1.7339995456044637, "CYMBALTA": 54.62596448720744, "DEXMEDETOMIDINE": 5.25714211792707, "ENTACAPONE": 4.927621321142853, "FENTANYL": 9.800891134834744, "IBUPROFEN": 1.2246085328326977, "IRON": 1.9462415944871745, "LEVODOPA": 4.847073654679399, "LYRICA": 2.1023597021723988, "MIDAZOLAM": 1.7249617660940113, "NALMEFENE": 80.94441726232563, "NALOXONE": 8.763207396830463, "OLANZAPINE": 1.4354817328471208, "OPIOIDS": 27.80155307735634, "OXYBUTYNIN": 2.716469793406256, "PREGABALIN": 1.218273546372452, "PRIALT": 24.6190452188728, "ROTIGOTINE": 51.14117313413747, "SELINCRO": 169.31686542854504, "SUBOXONE": 61.85913836699042, "XYREM": 2.070564829784533, "ZYPREXA": 1.6348853626651745, "null": 2.022715174889647}
\ No newline at end of file
+{"CLOPIDOGREL": 0.7853268910676738, "COMIRNATY": 0.6177469894375486, "CYMBALTA": 0.6009808392530142, "FORSTEO": 2.808218466459006, "GARDASIL": 0.8801452024484208, "NUCALA": 1.931112245366844, "OMALIZUMAB": 2.902193234491397, "SPIKEVAX": 0.3438685594525941, "SUTENT": 0.4607976338471529, "TOZINAMERAN": 0.6413044367666494, "VAXZEVRIA": 0.2599155479305509, "XOLAIR": 2.782763696931359, "null": 3.0738855243046643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2592.json
index e94d3ab990b..330a056bcdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2592.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2592.json
@@ -1 +1 @@
-{"ABILIFY": 5.645905256300755, "BENZODIAZEPINE": 31.410555451721237, "BUPRENORPHINE": 97.08059788737272, "BUVIDAL": 71.03492023019396, "CYMBALTA": 1.4783752530282042, "DEXMEDETOMIDINE": 20.131236801456076, "DULOXETINE": 2.7724898265166438, "FENTANYL": 5.2008662295247285, "KEPPRA": 1.525260857040773, "NALOXONE": 15.11581335382122, "NORVIR": 4.830257194988777, "OLANZAPINE": 3.501615035932806, "OPIATES": 140.61201824392026, "OPIOIDS": 121.97395366582086, "SUBOXONE": 141.42806566129036, "VIGABATRIN": 41.80210790722083, "ZYPREXA": 2.6115860446176558, "null": 2.1841858823059424}
\ No newline at end of file
+{"TAGRISSO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2593.json
index c3414a812cd..777f280abe4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2593.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2593.json
@@ -1 +1 @@
-{"null": 2.573367417528411}
\ No newline at end of file
+{"BYETTA": 10.526791795499086, "HARVONI": 17.663420147562075, "JANUMET": 8.908871978941528, "JANUVIA": 9.627784652677205, "NEXAVAR": 4.56239475175476, "VICTOZA": 23.73880556253168, "null": 0.6550036967122098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2594.json
index 8ef1c478808..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2594.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2594.json
@@ -1 +1 @@
-{"FENTANYL": 43.36408383041438, "null": 1.7958672730630731}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2595.json
index 96f046578cc..2b3bc4a12f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2595.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2595.json
@@ -1 +1 @@
-{"ABATACEPT": 2.112925007653574, "ABRAXANE": 2.0043875657427934, "ADALIMUMAB": 4.09110805089593, "AERIUS": 1.2243870492095723, "ALIMTA": 1.1110431655341833, "ALOXI": 9.20669275288271, "AMIKACIN": 3.294324043817761, "AMINOSALICYLIC": 2.005009463564893, "APREMILAST": 4.86332378173412, "APTIVUS": 6.756674975295933, "ARAVA": 1.1585957667536972, "ASPARAGINASE": 1.6309811848219578, "AXITINIB": 4.034734183319895, "AZATHIOPRINE": 2.1244589927835262, "BEDAQUILINE": 5.110726163095057, "BETAFERON": 1.9001077570149365, "BRAFTOVI": 1.4780220739386436, "BRIDION": 1.1710842568400956, "CANCIDAS": 6.379175637768167, "CAPECITABINE": 3.481188986492185, "CASPOFUNGIN": 4.901527538208074, "CELECOXIB": 1.4256388161652709, "CIMZIA": 1.8065514906978644, "CLADRIBINE": 1.9678806593324936, "CLOPIDOGREL": 2.684328374598619, "CRESEMBA": 4.101443683140849, "CUBICIN": 1.1084686530105277, "CYTARABINE": 2.026401104778914, "DELAMANID": 4.205598728586133, "DEXAMETHASONE": 1.3734052001134447, "DOCETAXEL": 1.5523669213052047, "DOXORUBICIN": 1.457531252797731, "EFAVIRENZ": 9.826149042804644, "EMTRICITABINE": 1.2065778313808584, "ENOXAPARIN": 3.8929336417149383, "ENTYVIO": 1.289740339543583, "ERTAPENEM": 11.6844180815453, "ESMYA": 2.246817455591321, "ESOMEPRAZOLE": 3.0521509343829667, "EXVIERA": 1.9097590145858008, "FASLODEX": 1.4807793999630543, "FEBUXOSTAT": 16.90077750493516, "FULVESTRANT": 1.1113810175000898, "FYCOMPA": 4.540196246850226, "GALVUS": 1.3835515486246015, "GEFITINIB": 6.502114492984986, "GLIBENCLAMIDE": 6.102421042908908, "HALAVEN": 3.1132428467023847, "HARVONI": 1.4621093017514186, "HERCEPTIN": 1.419770232489161, "IBUPROFEN": 2.5447539340758816, "INLYTA": 1.130714123445926, "IPILIMUMAB": 2.5067612910556094, "IRBESARTAN": 1.956729168845197, "IRESSA": 3.3954784381514456, "JANUVIA": 1.79134781018046, "KAFTRIO": 4.285687497838473, "KALETRA": 2.1512206564674687, "KETEK": 7.214618868755462, "KEYTRUDA": 2.516915528125013, "KISQALI": 1.5069209490233726, "LAMIVUDINE": 2.6132957782497845, "LEFLUNOMIDE": 5.118796236421479, "LENVIMA": 1.015041491656313, "LEVETIRACETAM": 1.6011189731974729, "LEVOFLOXACIN": 5.521010801650552, "LIRAGLUTIDE": 6.319059147574091, "LOPINAVIR": 2.8384233240783527, "LYRICA": 1.020794072927653, "MAVENCLAD": 2.164991269747034, "MERCAPTOPURINE": 4.53203541926135, "METHOTREXATE": 1.9894961710330263, "MICARDIS": 3.139033172190663, "MIDAZOLAM": 1.5204927869538434, "MULTAQ": 2.168802890220258, "NEVIRAPINE": 2.3634384908254806, "NEXAVAR": 1.132287396225989, "NOT": 2.1596278797698503, "NOVONORM": 1.7224620394028582, "NOXAFIL": 11.350082414503678, "OCALIVA": 1.6284252075657193, "OFEV": 1.045010061469427, "OLANZAPINE": 2.3838026552214964, "OLOPATADINE": 41.10149991505892, "OLYSIO": 1.5471230255077426, "OPDIVO": 4.198966253786695, "OSELTAMIVIR": 5.065667845388361, "PACLITAXEL": 4.177350083063442, "PANTOPRAZOLE": 1.028960435901778, "PAZOPANIB": 5.510970339677155, "PEMBROLIZUMAB": 3.328505832082729, "PEMETREXED": 1.994020776571908, "PLAVIX": 1.1460126280117746, "POSACONAZOLE": 3.070147702706404, "REMDESIVIR": 3.278399778694161, "RIBOCICLIB": 1.5435068656733932, "RIVAROXABAN": 2.306312553190929, "SIRTURO": 11.673509466573538, "SOMATROPIN": 10.747992718368042, "SORAFENIB": 1.977255535303854, "SOTORASIB": 10.625814518937682, "STIVARGA": 4.874893614331035, "SYCREST": 3.634151464170952, "TACROLIMUS": 2.439295289009844, "TAGRISSO": 1.3194721056203005, "TAMIFLU": 2.847283649830094, "TELMISARTAN": 1.3067549040539832, "TEMODAL": 1.459702360806572, "TEMOZOLOMIDE": 2.7360758674578536, "TENOFOVIR": 2.310163478860713, "TESTOSTERONE": 2.5714357885909904, "TIVICAY": 1.7679706676705045, "TOCILIZUMAB": 1.777332724881025, "TRACLEER": 1.0431227454438696, "TRIUMEQ": 5.9129766032483095, "UNKNOWN": 5.650622068051613, "VARENICLINE": 3.2120497651936293, "VEKLURY": 8.380741867219967, "VFEND": 4.810024743867458, "VICTOZA": 1.0148999968112349, "VORICONAZOLE": 16.48798107462812, "VOTRIENT": 1.8302059519118008, "XALKORI": 2.759747176665323, "XARELTO": 1.5225539710204443, "XELODA": 2.481271883611569, "YERVOY": 1.5266597881117463, "null": 2.0975507988261084}
\ No newline at end of file
+{"ABRAXANE": 15.685979048365702, "AFINITOR": 3.365525723288506, "BYETTA": 8.09432931521846, "CABOMETYX": 6.352951569570779, "CELLCEPT": 4.212306657472845, "CICLOSPORIN": 1.9154156425934392, "COMBIVIR": 6.734371444184069, "COMIRNATY": 0.0921559330935447, "ELIQUIS": 0.6862661786601543, "ENTYVIO": 2.339517191169831, "IRINOTECAN": 10.23085914144173, "JANUMET": 7.838766309569979, "JANUVIA": 6.2382858210847045, "JARDIANCE": 1.2382547164245332, "KEYTRUDA": 12.698527566623104, "LENVIMA": 31.238836287333168, "MEKINIST": 4.813190639270961, "NEXAVAR": 10.43012482591973, "OPDIVO": 9.07120859395352, "PEMBROLIZUMAB": 3.661292524588848, "SAXENDA": 3.1651063863210624, "SOLIRIS": 2.144495550562955, "SPIKEVAX": 0.0617809397135856, "STELARA": 1.5364113401951802, "STIVARGA": 7.163498903841889, "SUTENT": 1.501991889092748, "null": 0.8627950702444979}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2596.json
index 908d1bcb81b..7c0b469cb07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2596.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2596.json
@@ -1 +1 @@
-{"EYLEA": 122.15658948436617, "ZOSTAVAX": 28.504464586709105}
\ No newline at end of file
+{"BYETTA": 18.52911236636841, "KEYTRUDA": 4.793426084449924, "null": 1.072505455457701}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2597.json
index d154aa610fb..47791a46d77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2597.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2597.json
@@ -1 +1 @@
-{"ABATACEPT": 1.0609149431978395, "ABILIFY": 2.771828459275965, "AERIUS": 1.901557734230502, "AIMOVIG": 1.528914834874211, "AMGEVITA": 95.73546858846136, "ARAVA": 1.1044000225094566, "ARIPIPRAZOLE": 1.1263838266871702, "AVASTIN": 1.245669765675364, "AZATHIOPRINE": 1.2132712100309764, "BEOVU": 2.451368120452899, "BETMIGA": 6.721857575798488, "BRAFTOVI": 1.6596352367743212, "BRINTELLIX": 2.8256344247801564, "COAPROVEL": 1.4875884080768793, "COSENTYX": 2.0700465359581317, "DOCETAXEL": 1.7123736621463366, "DUPIXENT": 5.376112115363782, "ENBREL": 3.4568066204841483, "ENTYVIO": 1.0114758962673611, "ETANERCEPT": 11.645524700313649, "EVISTA": 1.275017195129991, "EYLEA": 3.499624143108395, "FASLODEX": 1.1063179965532786, "FULVESTRANT": 1.1485450951359208, "GARDASIL": 1.9160348976053443, "HUMIRA": 1.7291012315131988, "IBRANCE": 2.9500477398951688, "ICLUSIG": 3.6277618961705658, "IKERVIS": 34.10584149134583, "IMBRUVICA": 3.828423252415073, "IPILIMUMAB": 1.2312100942884137, "IVACAFTOR": 77.82005651515487, "JAKAVI": 1.0728024244332812, "KAFTRIO": 7.32673488039737, "KISQALI": 1.5496573640055478, "LEFLUNOMIDE": 4.9452024721361205, "LYRICA": 1.8225973057786224, "METHOTREXATE": 1.8026812242309096, "NEVANAC": 17.520869235384517, "NOT": 1.4290294590954853, "OMALIZUMAB": 1.1993921086927632, "OXYBUTYNIN": 5.631148755555689, "PEGASYS": 1.7413014023328366, "PEGINTERFERON": 1.9187828622369845, "PEGINTRON": 1.6776925287763689, "RIBAVIRIN": 1.0254585907312397, "TAGRISSO": 2.448772686386256, "TASIGNA": 1.352160500632228, "TOVIAZ": 10.75103012716396, "TOZINAMERAN": 1.0798943918842292, "XELJANZ": 1.7077922179188476, "XYREM": 2.591655121507472, "ZOSTAVAX": 6.100251831387898, "null": 1.2379674656921549}
\ No newline at end of file
+{"null": 0.3096098963220699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2598.json
index 61913ab3cbf..a19f22d3db9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2598.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2598.json
@@ -1 +1 @@
-{"INVOKANA": 226.4341849909896, "null": 1.983384624830825}
\ No newline at end of file
+{"ADALIMUMAB": 0.8383655866596947, "BUDESONIDE": 4.214940697976088, "CICLOSPORIN": 3.711290451419497, "COMIRNATY": 0.0883426393239939, "ENTYVIO": 31.77950780048792, "HUMIRA": 11.795799703317918, "KEYTRUDA": 59.75450838583468, "OPDIVO": 18.55649613057516, "PEMBROLIZUMAB": 16.055249456052806, "STELARA": 6.057003084439498, "null": 0.4318140289416732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2599.json
index 928ea628a4b..2395bc6ab29 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2599.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2599.json
@@ -1 +1 @@
-{"ABATACEPT": 4.109238286875727, "ABILIFY": 1.0238908320286748, "ADALIMUMAB": 3.87096804806446, "ADENURIC": 1.1906529283961835, "AERIUS": 5.158309234616886, "AFINITOR": 1.086606798596939, "AGOMELATINE": 5.464969975574975, "AIMOVIG": 1.1020954962959597, "ALDARA": 1.3107614720226626, "ALPELISIB": 1.6919277255235168, "ANORO": 1.5031514566391269, "APREMILAST": 3.4830221569089703, "APREPITANT": 1.9339034023644277, "APROVEL": 1.156965405699409, "ARANESP": 6.034141166184418, "ARAVA": 1.1517787342461825, "BETMIGA": 11.685931224457336, "BOTULINUM": 1.088882099573761, "BRINTELLIX": 2.2927465522187167, "CABOMETYX": 1.168147903925366, "CAPECITABINE": 1.2656614446357373, "CARBIDOPA": 4.424265119600345, "CERTOLIZUMAB": 4.220716192050152, "CHAMPIX": 1.7661146555388127, "CIRCADIN": 2.585894674187002, "COSENTYX": 1.0267887163971607, "CYMBALTA": 1.919401990676428, "DABRAFENIB": 1.8572659313106423, "DARBEPOETIN": 11.177851954948514, "DESLORATADINE": 2.15119287518281, "DULOXETINE": 2.017010368360685, "ELLAONE": 2.5397258692379583, "EMPAGLIFLOZIN": 1.5116494750013454, "ESMYA": 2.185215850047372, "EXFORGE": 1.1897124396052208, "FESOTERODINE": 8.070593073087295, "FLUTICASONE": 4.871587674098312, "FORXIGA": 4.296742544268177, "GALVUS": 1.321825133527674, "HYDROCHLOROTHIAZIDE": 1.660942979336251, "IBRANCE": 1.087962328023959, "IBUPROFEN": 1.7063805219734434, "INCRUSE": 2.0966926661652887, "INLYTA": 1.503254461468717, "INVEGA": 1.6036707196186113, "JARDIANCE": 2.362057715539907, "KENTERA": 11.516030169726738, "LATUDA": 1.0949653087929658, "LEFLUNOMIDE": 1.70110663130389, "LIRAGLUTIDE": 3.45381559092897, "LYRICA": 2.2889833656985075, "MELATONIN": 3.63572550439891, "MICARDIS": 1.580789259381763, "MICARDISPLUS": 4.474405118016654, "MIRABEGRON": 4.327617987246495, "OLANZAPINE": 1.2020904534622552, "OXYBUTYNIN": 13.988663184173207, "PANTOPRAZOLE": 1.1017441518519593, "PEGASYS": 1.7667062874065094, "PEGINTRON": 2.065606381219386, "PLUVICTO": 5.745062973842336, "PROTELOS": 1.0632688441582732, "RANEXA": 5.052210979262974, "REBETOL": 1.327623265928638, "RELVAR": 1.6977847724857713, "RISPERIDONE": 1.3427962811819585, "RYBELSUS": 1.208814090109586, "SAXENDA": 2.6159183987498835, "SIFROL": 1.3139652143960625, "STALEVO": 1.283645853923472, "SUTENT": 2.3029525638756594, "TELMISARTAN": 1.3304131434860942, "TOVIAZ": 21.3394156589005, "TRELEGY": 1.1252502851793282, "UMECLIDINIUM": 3.662890591879943, "UROREC": 14.863619091422716, "VIMPAT": 1.188571562117729, "XYREM": 1.455344981685701, "ZEJULA": 3.2620418374035376, "ZEPATIER": 1.4764942829314214, "ZYPADHERA": 1.147797540162952, "ZYPREXA": 1.1093482034617137, "null": 1.828664055236249}
\ No newline at end of file
+{"ARAVA": 0.8045707384000339, "AUBAGIO": 2.4090626936720563, "BENLYSTA": 2.596454991117624, "BYDUREON": 5.700716357378919, "BYETTA": 26.493886455999068, "CICLOSPORIN": 0.642828466406092, "CIMZIA": 1.308734610552036, "COMIRNATY": 0.0413964243669909, "CYMBALTA": 2.531339102615872, "DULOXETINE": 6.614017419597487, "ELIQUIS": 0.3709603685831046, "ENTYVIO": 2.7426735023365176, "EVISTA": 6.182675417725585, "EXJADE": 4.240231982325946, "FORSTEO": 1.5562975550109952, "GARDASIL": 0.6138619884871829, "HIZENTRA": 6.661901925390961, "HUMIRA": 2.647319857160583, "IBRANCE": 1.1689446130719277, "INSULIN": 2.034083591724163, "JANUMET": 30.068292523083308, "JANUVIA": 19.566339869656584, "JARDIANCE": 0.7417766136900351, "KEPPRA": 0.8784550017390602, "KEYTRUDA": 0.7232630102144094, "LANTUS": 1.793159073382708, "OPSUMIT": 3.47556108314884, "PEGASYS": 0.4579346776611362, "PEGINTRON": 2.655286764176956, "PLAVIX": 1.0381667743931398, "SAXENDA": 29.167290568733552, "SIMPONI": 2.8810418969989877, "SPIKEVAX": 0.0581845276943698, "STELARA": 4.730481599068673, "TRACLEER": 3.436167055841836, "TRELEGY": 2.328663684654314, "TREMFYA": 4.80760285122765, "VICTOZA": 6.528101061006101, "VOTRIENT": 2.0929049844502297, "XELJANZ": 0.8508333685863703, "XOLAIR": 0.8891507316671651, "ZOSTAVAX": 6.500064081378612, "null": 1.1438276469669075}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/26.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/26.json
index 9deef985af7..0302621973a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/26.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/26.json
@@ -1 +1 @@
-{"null": 1.5239202029864345}
\ No newline at end of file
+{"ABACAVIR": 0.4842928901600095, "ABASAGLAR": 1.685337015620538, "ABILIFY": 0.1583936338123385, "ABRAXANE": 0.8873090921906925, "ACLIDINIUM": 1.9639961023471737, "ADALIMUMAB": 3.045973043307656, "ADCIRCA": 3.6878005562341896, "ADEMPAS": 4.511819407257338, "ADENURIC": 1.2208411431394366, "AFINITOR": 1.5446931902658532, "AIMOVIG": 3.292101392059712, "ALEMTUZUMAB": 0.6310759249365604, "ALIMTA": 0.2104766530761768, "ALL": 2.357130840705633, "AMBRISENTAN": 1.4052485897836675, "AMINOSALICYLIC": 0.7990919830859318, "ANORO": 0.2996626869889517, "ANTIBIOTICS": 2.102098540673646, "APIDRA": 0.6020322795305869, "APREMILAST": 3.0218247559599405, "APREPITANT": 1.9837146168346984, "APROVEL": 0.440534573754866, "ARANESP": 18.73176238984267, "ARAVA": 0.789691363512377, "ARIPIPRAZOLE": 0.1752717022635435, "ASPARAGINASE": 0.8494153329312459, "ATAZANAVIR": 0.6025667259521457, "ATRIPLA": 0.0766669833149216, "AUBAGIO": 0.6131510772777697, "AVANDIA": 0.7831349017564213, "AVASTIN": 0.565841964220201, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/260.json
index 958942651d2..6f67beeb341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/260.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/260.json
@@ -1 +1 @@
-{"null": 1.4952445862083286}
\ No newline at end of file
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2600.json
index 08bc010c392..87ab8ff6dd6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2600.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2600.json
@@ -1 +1 @@
-{"AERIUS": 1.2114758877850458, "AFINITOR": 3.817373380609828, "APIXABAN": 12.245289559497731, "AUBAGIO": 1.7322585038232543, "BEDAQUILINE": 1.512127549242748, "BENLYSTA": 1.0829963372190676, "BIKTARVY": 1.203522448051511, "BOSULIF": 2.222251118786424, "BRAFTOVI": 2.3646452371718434, "CABOMETYX": 5.450024643836324, "CAPECITABINE": 1.9189712931557283, "CAPRELSA": 9.078980022181668, "COAPROVEL": 1.40729464907659, "CONTRAST": 21.77286039616827, "COSENTYX": 3.1681051714708093, "DABRAFENIB": 1.5463460130444664, "DUPIXENT": 5.382447301237019, "EMPAGLIFLOZIN": 2.0056512877454336, "ENTRESTO": 1.1344368754661631, "ENTYVIO": 1.8586527116462812, "ERBITUX": 6.654729430906476, "ERLEADA": 3.2248995108482728, "ESBRIET": 3.751695226407764, "EVEROLIMUS": 1.619943236992838, "FASLODEX": 3.128967825685466, "FORXIGA": 1.430588596176408, "FULVESTRANT": 3.1249402598627363, "GLIVEC": 2.430498185370144, "HERCEPTIN": 2.423594277497117, "HYDROCORTISONE": 2.5700438672489736, "IBRANCE": 6.848193142772971, "ICLUSIG": 8.639024360005838, "IMATINIB": 2.7122510713922305, "INCIVO": 4.504093809964141, "INLYTA": 4.9808813461295225, "IPILIMUMAB": 1.0745812391240983, "IRESSA": 8.01838755447787, "IRINOTECAN": 3.868846136362426, "JARDIANCE": 1.1290507625181618, "KEYTRUDA": 1.0063726386359693, "KISQALI": 6.189108316200277, "LIXIANA": 1.4442751763318027, "LONSURF": 1.5774389254427876, "LYNPARZA": 1.1772812149538652, "MEKINIST": 3.153320323456388, "MICARDIS": 1.0380314479698167, "NEXAVAR": 4.386110742939916, "NILOTINIB": 2.470110313204726, "NINLARO": 2.0652185055844936, "OLYSIO": 1.178629706444491, "OMALIZUMAB": 1.742747249965391, "OPDIVO": 1.0677784975289268, "OPTIMARK": 9.036452805451052, "OXYBUTYNIN": 2.4386337866298984, "PEGASYS": 5.326728429618185, "PEGINTERFERON": 4.629284477818826, "PEGINTRON": 3.585168494221376, "PEMBROLIZUMAB": 1.491812052686011, "REBETOL": 3.171585271804997, "RIBAVIRIN": 1.5001685335307948, "RUBRACA": 1.5438411595935386, "SIMPONI": 1.0472975757767595, "SPRYCEL": 1.7922150820454723, "STIVARGA": 2.1585553927001384, "SUTENT": 9.181740863655849, "TAGRISSO": 9.05282648504712, "TASIGNA": 3.0863657914500533, "TOVIAZ": 1.499190992976986, "TRAMETINIB": 11.59659415397186, "TRODELVY": 2.035998854606293, "VECTIBIX": 12.709833565517892, "VOTRIENT": 2.319082014165, "XTANDI": 1.4371753469735145, "ZELBORAF": 7.936653768709182}
\ No newline at end of file
+{"AFINITOR": 1.482448897480412, "ARAVA": 0.2228274454526643, "AUBAGIO": 1.270834259499905, "AVASTIN": 1.2517060836386915, "BUSULFAN": 1.5149751033385035, "BYDUREON": 1.015760900302768, "BYETTA": 7.171918699960036, "CABOMETYX": 2.288890179426065, "CELLCEPT": 1.6299426585845036, "CICLOSPORIN": 0.8382726384735949, "CIMZIA": 0.5768031569727002, "CLOPIDOGREL": 1.0704305116708397, "COMBIVIR": 4.319460760248536, "COMIRNATY": 0.1411985671225115, "CYMBALTA": 0.355513598660077, "CYTARABINE": 2.444960130502968, "DEXAMETHASONE": 1.6129904660558647, "EFIENT": 8.970764776553374, "ELIQUIS": 0.9687551805827112, "EXJADE": 2.362144882383937, "FORSTEO": 1.135914174597878, "FORXIGA": 1.2948693012293242, "IBRANCE": 0.4149932900571756, "IBUPROFEN": 1.0690568402671463, "INLYTA": 2.0777545468485665, "ISENTRESS": 5.504926426455712, "JANUMET": 5.362200249388299, "JANUVIA": 3.917782039632061, "JARDIANCE": 0.96730638138137, "KEYTRUDA": 5.822007725459072, "LANTUS": 0.9016474820109018, "LEMTRADA": 5.911342662459463, "LENVIMA": 23.69378658833244, "LEVETIRACETAM": 0.8737386913908431, "LYRICA": 1.168279569009732, "METHOTREXATE": 0.795361730976829, "MICARDIS": 1.7461134156214655, "NEXAVAR": 2.4764229365856085, "NORVIR": 6.794073087952374, "OFEV": 1.8388622247136672, "OPDIVO": 2.9151497116995624, "OPSUMIT": 1.4347945162568734, "OZEMPIC": 11.383905455905134, "PEGASYS": 1.514441465770046, "PEGINTRON": 1.5629658916769773, "PEMBROLIZUMAB": 2.175927106380916, "PLAVIX": 0.6988808637191414, "REVESTIVE": 36.47029122276876, "REYATAZ": 12.233773176654251, "ROACTEMRA": 2.118152357192602, "RYBELSUS": 7.918149716257222, "SAXENDA": 33.63457735568049, "SIMPONI": 1.5308969192635198, "SOLIRIS": 4.313681649176924, "SPIKEVAX": 0.1041911339098596, "STELARA": 1.2186379214238603, "STIVARGA": 3.506593248066369, "SUTENT": 3.4510964881742425, "TASIGNA": 1.7460254562641566, "TOZINAMERAN": 0.0984208239268052, "TRACLEER": 1.8306838527559928, "TRULICITY": 3.498049201045728, "VAXZEVRIA": 0.0886930545456457, "VFEND": 4.997080445856948, "VICTOZA": 8.162674666006826, "VOTRIENT": 1.0609874471938572, "ZYPREXA": 1.724009285352653, "null": 1.0182379178161045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2601.json
index 1cf01d2e50a..27070cd841d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2601.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2601.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 4.159068227391758, "AVAMYS": 1.4268612325229455, "BETMIGA": 5.28052200494966, "CAPECITABINE": 1.997903196453883, "CHAMPIX": 1.6735469490258228, "COMBIVIR": 2.482897451961384, "COVID19": 1.4475595628060318, "EXFORGE": 1.665513306796057, "GALVUS": 5.06631974949236, "INCRUSE": 5.337692142926777, "INLYTA": 1.8298213194425648, "METHOTREXATE": 1.0576437233644662, "OFEV": 1.7406576328220322, "OMALIZUMAB": 2.7475552889001618, "PEGASYS": 1.0867889554797818, "RELVAR": 9.742195190180274, "TOVIAZ": 19.85959229979885, "TOZINAMERAN": 1.8218041205124, "TRELEGY": 4.2910741247371895, "VOTRIENT": 2.1581839540940706, "XELJANZ": 1.373870810631193, "null": 1.7214996275428085}
\ No newline at end of file
+{"ANAKINRA": 8.315815666431817, "AVASTIN": 3.744037375387608, "BYETTA": 8.964901186281852, "CLOPIDOGREL": 2.0954035666194213, "COMIRNATY": 0.0949799310742409, "CYMBALTA": 0.7574203220241709, "CYTARABINE": 3.176263728869182, "INCIVO": 6.322766785277191, "JANUVIA": 2.938001639445291, "JARDIANCE": 1.3700025014404442, "KAFTRIO": 11.634704464958794, "KEYTRUDA": 5.795381278207016, "LEMTRADA": 11.903582654343415, "LENVIMA": 20.976946497177167, "NEXAVAR": 3.260053774123534, "PEGASYS": 1.9110417141459857, "PEGINTRON": 1.4152096997303314, "PLAVIX": 1.5132031524387637, "REYATAZ": 17.147099570275603, "ROACTEMRA": 2.7385345141903987, "SAXENDA": 16.040874763471027, "SOLIRIS": 2.094329216266205, "SPIKEVAX": 0.1103004335368715, "STELARA": 1.5579736209792618, "SUTENT": 1.8068951553296675, "TASIGNA": 2.670025341130067, "TRULICITY": 3.1154684804962995, "VAXZEVRIA": 0.0702924219917848, "VFEND": 5.6911204908364255, "VICTOZA": 13.510402089673386, "null": 0.9547989552081124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2602.json
index 0415ec35e6e..a6965f0fc3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2602.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2602.json
@@ -1 +1 @@
-{"BYETTA": 82.77309843270505, "JANUMET": 70.28352840302249, "JANUVIA": 102.99031407032784}
\ No newline at end of file
+{"BEDAQUILINE": 47.86832925553114, "BYETTA": 39.24058079973306, "CELLCEPT": 6.373639098723926, "JANUMET": 24.61756925538015, "JANUVIA": 14.426656911212511, "null": 2.6653195776971548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2603.json
index 1c294257206..8e22981d605 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2603.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2603.json
@@ -1 +1 @@
-{"null": 5.481454892736287}
\ No newline at end of file
+{"COMIRNATY": 0.100607106144525, "SUTENT": 5.337647260819533, "null": 0.8167108042248379}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2604.json
index ab2a17eb7c5..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2604.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2604.json
@@ -1 +1 @@
-{"null": 6.683113646453936}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2605.json
index 89ddc9b44e8..19476554c10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2605.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2605.json
@@ -1 +1 @@
-{"null": 1.3668662116404804}
\ No newline at end of file
+{"ABACAVIR": 0.370299675753214, "ACLIDINIUM": 24.42525250159686, "ADCIRCA": 2.6940427654210564, "AFINITOR": 1.2406272878490443, "AIMOVIG": 0.4642956314184226, "ALIMTA": 0.7785092581063388, "ANORO": 1.4039845102063593, "APIDRA": 1.265170215403371, "APROVEL": 1.4707323150977265, "APTIVUS": 41.75148063711991, "ARANESP": 0.3335462416072473, "ARAVA": 0.1573276164751119, "ARIPIPRAZOLE": 0.5328043727983217, "ATAZANAVIR": 3.727690551645369, "ATRIPLA": 0.1376312038475552, "AUBAGIO": 0.9105067848680491, "AVANDIA": 0.2929714092692955, "AZATHIOPRINE": 0.7016841148441973, "BENLYSTA": 1.23896019754815, "BEVACIZUMAB": 0.6909214798215916, "BOSUTINIB": 6.977298447405228, "BYDUREON": 3.158734111083962, "BYETTA": 18.790855081611348, "CELECOXIB": 8.545022484868394, "CELLCEPT": 1.118732655249428, "CHAMPIX": 0.3314652657909385, "CICLOSPORIN": 0.5267286946703784, "CIMZIA": 0.9003830446581677, "CINACALCET": 8.787950398606334, "CLOPIDOGREL": 0.843974970245946, "COMBIVIR": 1.3848575882334349, "COMIRNATY": 0.058683780624293, "COSENTYX": 0.3246903793107463, "CYMBALTA": 0.4774609845349654, "CYTARABINE": 0.9261867957021922, "DEXAMETHASONE": 1.055407269489154, "DOCETAXEL": 0.585290210536436, "DULOXETINE": 0.921559098061376, "ELIQUIS": 0.5928554528768802, "ENTRESTO": 0.6642431394418239, "ENTYVIO": 0.8684233975811844, "ESBRIET": 1.550846129843923, "EVISTA": 1.687256036462938, "EXFORGE": 3.0221227854450223, "EXJADE": 4.806846350703177, "EXVIERA": 2.8851364449251573, "FAMPYRA": 1.5524186136221136, "FASLODEX": 0.8283356179895991, "FENTANYL": 0.3404028922465958, "FORSTEO": 3.3551089132951804, "FORXIGA": 0.9049943756617912, "GALVUS": 7.079927220126869, "GARDASIL": 0.5471945559916335, "HUMALOG": 1.2966898587712328, "HUMIRA": 0.5556798607933576, "IBRANCE": 1.1154646845088998, "IBUPROFEN": 0.5860261737282622, "INLYTA": 0.6871218904063945, "ISENTRESS": 5.173663702654479, "JAKAVI": 1.9034326780823425, "JANUMET": 12.197014290731056, "JANUVIA": 10.612519155420008, "JARDIANCE": 0.6921461489285899, "KAFTRIO": 3.9111688919837935, "KALETRA": 1.401444773488924, "KEPPRA": 0.4655771902981072, "KEYTRUDA": 0.4804712565179176, "KIVEXA": 7.463124612674903, "LANTUS": 0.7429960911107044, "LEMTRADA": 0.7933280702295705, "LEVEMIR": 1.9320915364527231, "MEPOLIZUMAB": 0.4081400697912914, "METHOTREXATE": 2.0919710626823296, "MICARDIS": 2.0000507388136493, "NEXAVAR": 0.4329656328588725, "NORVIR": 9.640760788165757, "NOVORAPID": 0.5498456466220507, "NPLATE": 1.4039258387797509, "NUCALA": 0.4558123848059242, "OCALIVA": 3.0490047592324063, "OCTREOTIDE": 19.996518143655745, "OFEV": 0.8283298578609126, "OLANZAPINE": 0.3329978069651054, "OMALIZUMAB": 1.5174490275694552, "ONGLYZA": 3.501837010707145, "OPSUMIT": 1.1532082696916293, "OPTIMARK": 0.4298244501012821, "OZEMPIC": 5.807710504197421, "PANTOPRAZOLE": 2.03816057378182, "PEGASYS": 1.8355933127403212, "PEGINTERFERON": 0.6972894776489462, "PEGINTRON": 0.9219781282165764, "PLAVIX": 0.6020196804619702, "REMICADE": 2.478143464855872, "REYATAZ": 29.8601114088961, "RINVOQ": 0.5530832218791012, "RITUXIMAB": 0.9586488202447307, "ROACTEMRA": 0.5922344896311451, "RYBELSUS": 10.993608628219876, "SAXENDA": 49.67993708648, "SIMPONI": 1.529888417800353, "SOLIRIS": 6.006089678134395, "SOVALDI": 1.7599041867614893, "SPIKEVAX": 0.0662021445895702, "SPINRAZA": 1.480374258171984, "STELARA": 1.6692177043115095, "SUBOXONE": 1.286401582121217, "SUTENT": 1.2595230713295889, "TASIGNA": 1.8508875332860912, "TOZINAMERAN": 0.1499414667581503, "TRACLEER": 2.0824844979410857, "TRULICITY": 6.044942800254252, "TRUVADA": 0.1057193171320704, "VAXZEVRIA": 0.0412033605348872, "VELTASSA": 1.5307346016402, "VFEND": 1.3049680818287412, "VIAGRA": 0.8877245016587892, "VICTOZA": 17.570873763067, "VOTRIENT": 0.9088153164726552, "XELJANZ": 1.3741522415440686, "XOLAIR": 0.7621264609607575, "XTANDI": 0.4692005812086683, "ZOMETA": 5.003313386098775, "ZOSTAVAX": 0.8776185334420024, "ZYPREXA": 2.2814739803491992, "null": 1.2895250591088898}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2606.json
index bb18a6bd9bb..14a1eea5473 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2606.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2606.json
@@ -1 +1 @@
-{"BYETTA": 41.2908445716403, "CYTARABINE": 35.94525437583702}
\ No newline at end of file
+{"null": 0.5421702344923595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2607.json
index 48362e208f6..c01f068e336 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2607.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2607.json
@@ -1 +1 @@
-{"AVASTIN": 34.62008105327172, "BEDAQUILINE": 34.31028382411531, "KEYTRUDA": 9.332664121602413, "LENVIMA": 42.479587530942695, "STIVARGA": 17.84452260203771, "SUTENT": 2.306487337593943}
\ No newline at end of file
+{"null": 1.185351215009184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2608.json
index c457f182046..2455677dee5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2608.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2608.json
@@ -1 +1 @@
-{"null": 1.4712875473048062}
\ No newline at end of file
+{"ABACAVIR": 0.6017522388847758, "ADENURIC": 5.3979945773698885, "AERIUS": 3.653757280796487, "AFINITOR": 0.3986869954450562, "ALIMTA": 2.7498367473777408, "ALOXI": 19.729984872759196, "AMIKACIN": 1.9886208205663296, "APROVEL": 2.178512795890986, "ARAVA": 0.1539021414580858, "ARIXTRA": 5.817716679103597, "ASPARAGINASE": 4.655123164463696, "ATAZANAVIR": 2.390505249997665, "ATRIPLA": 0.1867440280023739, "AUBAGIO": 0.3393579105711267, "AVANDIA": 0.3425363941052852, "AVASTIN": 2.1480673925945566, "AZATHIOPRINE": 1.0728987422681635, "BIKTARVY": 0.8544692569040571, "BRAFTOVI": 2.4387481631134635, "BRILIQUE": 2.1473134628560486, "BRINTELLIX": 0.6934341537276718, "BRIVIACT": 1.7793704193099762, "BUSULFAN": 0.9795348483856154, "BYETTA": 0.386886698756637, "CABOMETYX": 0.9723700654136752, "CAELYX": 1.421342713670884, "CANCIDAS": 17.967073155052127, "CANNABIDIOL": 4.561354074717738, "CASPOFUNGIN": 3.527023443307823, "CELLCEPT": 2.833708272340033, "CICLOSPORIN": 1.3872360820131366, "CIMZIA": 0.1121430935095041, "CLOPIDOGREL": 1.1242292370310454, "COAPROVEL": 2.7001124470919065, "COMBIVIR": 2.945362665321805, "COMIRNATY": 0.0330199321979881, "COTELLIC": 11.8751675120925, "CUBICIN": 2.4078672848134346, "CYMBALTA": 0.4486283110415178, "CYTARABINE": 1.0685051672038357, "DARZALEX": 1.151604926874182, "DEXAMETHASONE": 0.8565248741270578, "DULOXETINE": 0.6407988397742669, "EFAVIRENZ": 2.209900875586501, "ELIQUIS": 1.1274591867221924, "EMEND": 4.9458198199253, "EMTRICITABINE": 2.709380811195733, "ENOXAPARIN": 1.3699655956430736, "ENTRESTO": 0.76630832716235, "ENTYVIO": 0.8773481026772566, "EPIVIR": 2.3943419227750757, "ESBRIET": 0.6084160796206407, "ESOMEPRAZOLE": 5.364939659629719, "EUCREAS": 2.4232999562892514, "EXFORGE": 0.8182544927628468, "EXJADE": 0.8361400856325696, "FORSTEO": 0.4658170567634599, "FUZEON": 30.52912981358692, "GALVUS": 5.324503364868519, "GANCICLOVIR": 2.407620749303092, "GLIVEC": 2.728410474128639, "IBUPROFEN": 1.7252746220205906, "ICLUSIG": 1.037919814185937, "IMBRUVICA": 4.457303047739548, "INLYTA": 0.4777864577534177, "INSULATARD": 5.684249792751863, "IPILIMUMAB": 1.1337674161217224, "IRBESARTAN": 3.539711827522515, "ISENTRESS": 2.488034166033142, "ISOPHANE": 10.343487952075716, "JAKAVI": 0.6942751890836829, "JANUMET": 1.0966922548356672, "JANUVIA": 1.2054402121441496, "KAFTRIO": 1.475305999573638, "KALETRA": 6.010254596558652, "KEPPRA": 5.181789874253369, "KEYTRUDA": 1.3936449119264431, "KISQALI": 1.741480749654411, "LACOSAMIDE": 1.219592951259355, "LANTUS": 0.3614141179045677, "LEVETIRACETAM": 1.3061508764605758, "LEVOFLOXACIN": 0.9376656069540976, "LUMYKRAS": 18.831227719531736, "LYRICA": 2.4178170218807864, "MEKINIST": 4.681211367798367, "MERCAPTOPURINE": 2.5654483083139743, "METHOTREXATE": 1.0885506039634425, "MICARDIS": 0.8691800507988237, "MIDAZOLAM": 4.4439119738350135, "NEXAVAR": 0.5141998537464302, "NORVIR": 8.065466469323013, "NOVONORM": 4.777065640616162, "NOVORAPID": 0.5418930475620943, "NOXAFIL": 14.473180428141289, "OCALIVA": 3.2684359384226678, "OFEV": 1.382538205536249, "OLANZAPINE": 0.7139039335762565, "OPDIVO": 2.398980272128844, "PANTOPRAZOLE": 6.453185437236232, "PEGASYS": 0.5849709083196541, "PEGINTERFERON": 0.6804065555757656, "PEMBROLIZUMAB": 1.4620101775885523, "PLAVIX": 1.5248513146545446, "POSACONAZOLE": 5.063814515427367, "PREGABALIN": 2.75280025488788, "REBETOL": 2.0124431549484507, "REVATIO": 1.0436361940012078, "REYATAZ": 3.2666343409498584, "ROACTEMRA": 1.3569057363171997, "SIMPONI": 0.3473128307096271, "SOLIRIS": 1.1334668692961307, "SPIKEVAX": 0.0102732644237631, "STELARA": 0.2338234067578697, "STIVARGA": 0.6863080798603837, "SUFENTANIL": 6.9087089196938845, "SUTENT": 0.2902319939306739, "TAMIFLU": 3.3356283298895386, "TASIGNA": 0.5634375304182915, "TEMODAL": 10.19912620418355, "TEMOZOLOMIDE": 3.2985823658421487, "TESTOSTERONE": 3.101375735972487, "TIVICAY": 2.9158428083437973, "TRACLEER": 1.946310929417409, "TRULICITY": 0.4135532131862844, "VAXZEVRIA": 0.0141363639756048, "VEKLURY": 6.909293019990626, "VFEND": 17.574682987499127, "VIMPAT": 1.005087735168554, "VIRAMUNE": 4.318429006362471, "VORICONAZOLE": 9.493769963397629, "VOTRIENT": 1.7656696565209162, "XARELTO": 2.386691429780636, "XELODA": 1.7196554057617397, "YERVOY": 1.381495516994069, "YONDELIS": 8.78889935741572, "ZELBORAF": 2.540538814595917, "ZYPREXA": 0.7860748803908162, "null": 2.4028311887624807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2609.json
index 0fdddc0b29c..7cf6e66a6e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2609.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2609.json
@@ -1 +1 @@
-{"null": 1.4385298675241605}
\ No newline at end of file
+{"DULOXETINE": 59.216874720782485, "null": 0.8037916861832554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/261.json
index 35968d05f75..67bc80f6595 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/261.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/261.json
@@ -1 +1 @@
-{"BRIDION": 177.21617286771666, "FENTANYL": 43.75810272349158, "MIDAZOLAM": 85.7424050434213, "null": 2.9603906551004995}
\ No newline at end of file
+{"AFATINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2610.json
index e15a413a332..3440547c570 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2610.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2610.json
@@ -1 +1 @@
-{"AVASTIN": 3.3403461977729365, "BRILIQUE": 7.862181802600708, "BYETTA": 3.5073088472060245, "CELLCEPT": 2.6607221505039784, "CLOPIDOGREL": 14.145456916298343, "DARUNAVIR": 24.3667078257071, "DEXAMETHASONE": 1.0249962235605916, "ELIQUIS": 3.8330296984956895, "EXJADE": 5.436534657061409, "IBUPROFEN": 3.2581955401523253, "JAKAVI": 1.5682173036959637, "JANUMET": 1.696902547863694, "JANUVIA": 3.7594226531965895, "KEYTRUDA": 2.4980881873720278, "LENVIMA": 4.282201277694157, "LIXIANA": 4.25094939236723, "MEKINIST": 1.8850772701972809, "NEXAVAR": 1.6519670680009275, "OPDIVO": 2.243668147278874, "PANTOPRAZOLE": 3.553693230843065, "PLAVIX": 12.413672636828542, "SUTENT": 1.2319850295673622, "TAMIFLU": 2.650652489980656, "TICAGRELOR": 15.889728071557718, "VOTRIENT": 1.7401765809713197, "null": 1.9671623327480157}
\ No newline at end of file
+{"BRIDION": 24.5362067467291, "COMIRNATY": 0.0493153472697725, "ELIQUIS": 2.4244631029769543, "KEYTRUDA": 2.3967148765540047, "LEVETIRACETAM": 5.056525154829041, "MULTAQ": 21.13172429581888, "PLAVIX": 2.6428081537453547, "null": 2.7279154338249696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2611.json
index b6eba205097..fbf49f8aae7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2611.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2611.json
@@ -1 +1 @@
-{"AVASTIN": 5.8394109725486905, "BRILIQUE": 5.752822123621036, "CLOPIDOGREL": 21.64267972970896, "EFIENT": 25.76456135924674, "ELIQUIS": 5.812450062267315, "EXJADE": 3.8422594154079657, "IBUPROFEN": 3.7089857890137634, "LENVIMA": 8.061933411146926, "LIXIANA": 8.003096730405808, "NEXAVAR": 2.3628842627026434, "PLAVIX": 28.28715668362136, "TAMIFLU": 3.357202942013878, "TICAGRELOR": 32.86101281959504, "XARELTO": 14.474002180915386, "null": 1.7142809376972643}
\ No newline at end of file
+{"null": 1.102950366923506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2612.json
index a8ddc143a30..6f40b7de540 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2612.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2612.json
@@ -1 +1 @@
-{"ABATACEPT": 28.070132257286875, "ACETAMINOPHEN": 67.64089812316634, "ADALIMUMAB": 45.01902211086765, "APREMILAST": 23.935253822625956, "APREPITANT": 90.4668098392763, "ARAVA": 34.065418763154184, "CIMZIA": 4.919933726969172, "COSENTYX": 2.0646421585826, "ERELZI": 12.191558605162614, "HUMIRA": 1.6072921741014827, "HYDROCORTISONE": 2.440794762166317, "MYCOPHENOLATE": 3.714255700967463, "RITUXIMAB": 4.016529489487501}
\ No newline at end of file
+{"null": 1.5854446637012745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2613.json
index ba650ed4226..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2613.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2613.json
@@ -1 +1 @@
-{"ADCIRCA": 24.60719711684903, "BYETTA": 13.78139755827861, "CHAMPIX": 1.5075632956929856, "CLOPIDOGREL": 10.954179234659096, "DACLATASVIR": 42.56792082718861, "ELIQUIS": 1.4005917235350052, "FENTANYL": 2.5523132622547764, "INFLIXIMAB": 19.40263865414012, "IPILIMUMAB": 20.940303671947945, "JANUMET": 3.3936206974807925, "JANUVIA": 2.692060788775488, "KEYTRUDA": 2.7261153521413832, "METHOTREXATE": 4.294912259135163, "OPDIVO": 8.178438769507647, "PLAVIX": 5.498682416117826, "SUTENT": 1.3753301382303793, "null": 1.1710622155509371}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2614.json
index 6015208534e..de55d62633b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2614.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2614.json
@@ -1 +1 @@
-{"null": 3.933202838056386}
\ No newline at end of file
+{"BEOVU": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2615.json
index 27d434c33c0..2057f6f84f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2615.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2615.json
@@ -1 +1 @@
-{"ACLIDINIUM": 82.26474012607873, "BIKTARVY": 35.86342570000992, "COLLAGENASE": 3283.2422052339657, "XIAPEX": 1015.0574975032964, "ZOSTAVAX": 4.910147733224104, "null": 1.2608485726643286}
\ No newline at end of file
+{"null": 0.7934161955149596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2616.json
index 444eb1152f7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2616.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2616.json
@@ -1 +1 @@
-{"ACLIDINIUM": 4289.238193960354}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2617.json
index 792d2cdab5d..ae198992ef7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2617.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2617.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4264243142985773}
\ No newline at end of file
+{"COMIRNATY": 0.1798439665404682, "IRINOTECAN": 45.525452936625705, "TRODELVY": 60.423254645511584, "null": 7.842590819670445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2618.json
index e87b517632b..9749385cf95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2618.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2618.json
@@ -1 +1 @@
-{"ABILIFY": 4.110600996032065, "ANORO": 778.6771379219762, "APIXABAN": 116.63243306983888, "AVAMYS": 33.820685612502025, "AZATHIOPRINE": 33.738508942202245, "OMALIZUMAB": 33.6791259042143, "PANTOPRAZOLE": 25.50882618684002, "UMECLIDINIUM": 89.86795318643874}
\ No newline at end of file
+{"null": 1.7765710318835526}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2619.json
index c57232a4ba2..50792138d62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2619.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2619.json
@@ -1 +1 @@
-{"null": 1.0073536249268118}
\ No newline at end of file
+{"METHOTREXATE": 79.50936480548413, "null": 0.2809334119715149}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/262.json
index 5fa811134f1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/262.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/262.json
@@ -1 +1 @@
-{"BRIDION": 229.82135865159088, "FENTANYL": 104.37878587281892, "null": 1.823159299671001}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2620.json
index ae0c250e2ea..7e6834dd253 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2620.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2620.json
@@ -1 +1 @@
-{"COMIRNATY": 1.009046639396656}
\ No newline at end of file
+{"ANAKINRA": 85.67291488676655, "AVAMYS": 58.79407272209976, "COMIRNATY": 0.3732139346100001, "null": 0.3818941239503045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2621.json
index 4d2ae48040f..35a566c5409 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2621.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2621.json
@@ -1 +1 @@
-{"AMIKACIN": 3.7800801003837576, "ANAGRELIDE": 73.24290938521547, "AUBAGIO": 2.122148773838767, "CAPECITABINE": 1.937291093940108, "COMIRNATY": 3.0784989660561908, "GARDASIL": 3.5214856124315714, "SHINGRIX": 2.8905713208285144, "SPIKEVAX": 1.238641247797874, "STIVARGA": 1.103367830460705, "THALIDOMIDE": 4.974378184157472, "TWINRIX": 5.055151893154581, "VAXZEVRIA": 1.3813582921826213}
\ No newline at end of file
+{"AVAMYS": 34.84123268429518, "COMIRNATY": 0.1579650237401265, "RELVAR": 93.2131983123444, "null": 1.1192810513180964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2622.json
index 037f5b7d03b..5b9048404fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2622.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2622.json
@@ -1 +1 @@
-{"null": 12.772471136345011}
\ No newline at end of file
+{"METHOTREXATE": 433.167344988291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2623.json
index 1ffebc51a08..b5fffaf4307 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2623.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2623.json
@@ -1 +1 @@
-{"null": 1.359417735449565}
\ No newline at end of file
+{"ENTYVIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2624.json
index b48b9f74860..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2624.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2624.json
@@ -1 +1 @@
-{"ABILIFY": 1.7839309952111004, "ALISKIREN": 33.258109450506424, "ARIPIPRAZOLE": 2.417256057479589, "AUBAGIO": 1.3838058267322704, "AZILECT": 5.983267079969332, "BENRALIZUMAB": 3.1878529309639005, "BRIVARACETAM": 3.353894036007678, "BRIVIACT": 1.4840408429372889, "BUPRENORPHINE": 2.549257259709028, "CANNABIDIOL": 4.220369824274967, "CAPECITABINE": 1.1757254118476503, "CHAMPIX": 1.770234071876231, "CYMBALTA": 1.204272530115934, "DULOXETINE": 1.487072749262761, "EFAVIRENZ": 1.3132526026272155, "EMTRIVA": 3.73013279505712, "ENOXAPARIN": 1.3455233748413251, "EPIVIR": 1.5424026227622454, "EUCREAS": 1.4403196633378437, "EYLEA": 1.7200791281702714, "FAMPYRA": 1.6047601660346869, "FENTANYL": 2.4714655861900905, "FIRDAPSE": 1.7435303034040817, "FYCOMPA": 7.500747393907536, "GLIBENCLAMIDE": 1.6689582009955672, "IBUPROFEN": 1.122239975820561, "INTELENCE": 3.421208629107179, "IRBESARTAN": 1.1123180461892537, "IRINOTECAN": 7.504346796065818, "KEPPRA": 2.5200735864380253, "KYMRIAH": 1.2166280895248314, "LACOSAMIDE": 2.302824382642821, "LATUDA": 2.317266486983779, "LEVETIRACETAM": 1.811238677126468, "LEVODOPA": 2.453991309162341, "LYRICA": 2.7879703718715305, "MELATONIN": 1.239943225933003, "METFORMIN": 1.2297830458457784, "NALOXONE": 4.290598408555982, "NILOTINIB": 1.5586967505031115, "NOVONORM": 3.80569693573888, "OLANZAPINE": 4.363400018441745, "OXYBUTYNIN": 2.1413836295883426, "PREGABALIN": 5.006100644134078, "RISPERIDONE": 4.998529316077903, "STALEVO": 1.2684708139463658, "SYCREST": 11.53932727711263, "TAMIFLU": 1.0759891521764506, "TASIGNA": 1.266112245866841, "THALIDOMIDE": 1.0089258690588887, "TOZINAMERAN": 1.0323071964073678, "VALDOXAN": 6.116331297362772, "VIMPAT": 2.353309594413144, "ZYPADHERA": 58.70617919143494, "ZYPREXA": 2.852999275591684, "null": 2.146945856375951}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2625.json
index 7a46f9f1eb5..66add7ee5da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2625.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2625.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 9.295240045622233, "BUSULFAN": 43.407374055249264, "LEVOFLOXACIN": 20.051264052504667, "null": 2.344158679059403}
\ No newline at end of file
+{"DONJOY": 83876.61688034111, "IFLOW": 44027.57818524235, "null": 0.9283903319464908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2626.json
index be249fcff05..9fbbc8f4b40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2626.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2626.json
@@ -1 +1 @@
-{"null": 3.7203553065899935}
\ No newline at end of file
+{"null": 1.7094405736763596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2627.json
index 63a84371b7b..ccb20814a20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2627.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2627.json
@@ -1 +1 @@
-{"AIMOVIG": 7.027550279297166, "ELIQUIS": 2.2880939456429297, "ENTYVIO": 12.19528821152895, "GARDASIL": 1.557564057561343, "HUMIRA": 10.088663416404128, "IBRANCE": 1.344386232368468, "PEGASYS": 3.7787155897268376, "SUTENT": 3.758211698030864, "XELJANZ": 1.9311752578141472, "null": 1.3565012611300968}
\ No newline at end of file
+{"null": 1.0088296720616217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2628.json
index c5a8b504712..a81db8d0b4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2628.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2628.json
@@ -1 +1 @@
-{"JETREA": 1303.6266700816795, "KEPPRA": 2.3415591959483297, "SILDENAFIL": 23.04524250915977, "TOZINAMERAN": 1.0371790775383178, "VFEND": 73.01145294112155, "VIAGRA": 19.35378657567842, "VORICONAZOLE": 31.31668213202654}
\ No newline at end of file
+{"LENVIMA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2629.json
index 26b46a4f8ce..9e8da4dfabb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2629.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2629.json
@@ -1 +1 @@
-{"ABACAVIR": 17.0516850194585, "null": 2.617736458462352}
\ No newline at end of file
+{"ARAVA": 4.359068067073433, "COMIRNATY": 0.1101473082253032, "ELIQUIS": 1.575461459508673, "ESOMEPRAZOLE": 25.655103962356492, "SIMPONI": 6.799798958327733, "VIAGRA": 9.134824202803769, "XELJANZ": 5.71163913905201, "null": 1.3708089809254822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/263.json
index a17aacc52be..c57e8f75afa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/263.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/263.json
@@ -1 +1 @@
-{"MEPOLIZUMAB": 95.16366625481815, "METHOTREXATE": 339.58378892615184}
\ No newline at end of file
+{"COMBIVIR": 477.097705543272, "null": 0.5493606915758263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2630.json
index ba0fd8d9383..a034b55f4fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2630.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2630.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9665359043615367, "FORSTEO": 4.168522765881235, "SUTENT": 5.161426751683807, "VAXZEVRIA": 1.3816982375960745, "null": 1.1652084830544658}
\ No newline at end of file
+{"null": 0.4628365705705682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2631.json
index 8489f2c5dae..25c6eb2add4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2631.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2631.json
@@ -1 +1 @@
-{"AFINITOR": 1.277134751397538, "AIMOVIG": 1.602684064389178, "APROVEL": 1.8548924792204144, "BOCEPREVIR": 6.934465018242256, "BRINTELLIX": 1.5959702094768795, "CABOMETYX": 3.64250719875444, "CAPECITABINE": 1.3147622616486117, "CHAMPIX": 2.2661788981383824, "COAPROVEL": 1.766631643510123, "COMIRNATY": 1.289593002620201, "COTELLIC": 1.376925445363407, "COVID19": 1.4645589807873691, "DUAKLIR": 33.53294712539142, "ESBRIET": 1.2645537072964512, "EUCREAS": 1.104119113268106, "FASLODEX": 1.468013341602605, "FORXIGA": 1.3196090840875936, "HERCEPTIN": 1.423988956891861, "IBRANCE": 1.282752685454655, "INCIVO": 1.7541562329244291, "INCRUSE": 1.194590142298889, "INLYTA": 1.431118092717731, "INVIRASE": 2.7742211693576886, "IRBESARTAN": 2.042372789268117, "IRINOTECAN": 1.240199153090746, "JARDIANCE": 1.135530895483019, "JEVTANA": 1.7048426118793605, "JORVEZA": 14.826606885304164, "KISQALI": 1.3412967368512352, "LYNPARZA": 1.7739603780139412, "MICARDIS": 1.1882036728586922, "PANTOPRAZOLE": 1.0919014752976957, "PAXLOVID": 17.681183237595107, "PAZOPANIB": 1.073578734012128, "PEGASYS": 2.6576526095404804, "PEGINTERFERON": 1.881000379701021, "PEGINTRON": 4.881739417072375, "QUTENZA": 1.400358455524194, "REBETOL": 1.0257755022804746, "RELVAR": 1.2133335284473517, "RUBRACA": 8.58117751879402, "RYBELSUS": 3.839344309021025, "SAXENDA": 1.2721658484320453, "SUTENT": 3.3466316481267917, "SYCREST": 10.523392391982188, "TAGRISSO": 1.6529897116311794, "TOZINAMERAN": 1.5150082334198407, "TRELEGY": 1.2181296388994378, "VOTRIENT": 2.4895757228936373, "XALKORI": 3.847660958208119, "XTANDI": 1.168772824549072, "ZELBORAF": 2.6864448286956706, "null": 1.3963385481966313}
\ No newline at end of file
+{"null": 0.8325331525086475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2632.json
index a5ceb143135..671f4d42c0f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2632.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2632.json
@@ -1 +1 @@
-{"AUBAGIO": 2.5226936651410585, "CAELYX": 6.83519294491055, "FAMPYRA": 4.572940615291889, "GARDASIL": 1.4257441427741488, "IBRANCE": 1.6764978217696562, "KEPPRA": 2.641776334911854, "KYMRIAH": 11.160270710439791, "LANTUS": 2.4000154317689018, "PLAVIX": 2.432414536987068, "TOVIAZ": 6.4057347398106215, "XELJANZ": 3.483490520546, "YESCARTA": 49.00119438871456, "ZYPREXA": 1.8091456504062484, "null": 2.5887014094247687}
\ No newline at end of file
+{"null": 3.949427814485976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2633.json
index ecc5c3951e3..b4d04d1b936 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2633.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2633.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1077537915627482, "COSENTYX": 8.783593857812683, "HUMAN": 27.70027244521391, "PRIVIGEN": 26.660673261154635, "TOZINAMERAN": 1.2866244327723717}
\ No newline at end of file
+{"ABACAVIR": 3.7998022292620703, "COMIRNATY": 0.1291054011512164, "GARDASIL": 2.1317744436119708, "INSULIN": 5.567275089227602, "OLANZAPINE": 4.670211873378628, "PEGASYS": 2.4858534341170944, "null": 2.782918053871488}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2634.json
index c68407c1cf8..d83eefde2fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2634.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2634.json
@@ -1 +1 @@
-{"ABILIFY": 15.692865848775693, "AERIUS": 1.398992307317391, "ARIPIPRAZOLE": 5.893708788309645, "AZILECT": 37.07866629272099, "BENZODIAZEPINES": 29.36753253356509, "BOTULINUM": 1.9777644403599783, "BRINTELLIX": 1.8460477446957968, "BRIVIACT": 1.7298805049673989, "BUPIVACAINE": 1.295830939602201, "CANNABIDIOL": 2.270507392317191, "CARBIDOPA": 23.339915167735445, "COMTAN": 37.02323090008107, "COMTESS": 29.66992297410299, "CYMBALTA": 2.348201589148452, "DEXMEDETOMIDINE": 10.141396308326074, "DULOXETINE": 2.688688273937133, "ENTACAPONE": 63.78020925244957, "FENTANYL": 2.161877941377553, "FYCOMPA": 3.749273033091782, "GARDASIL": 5.982727196062557, "INBRIJA": 22.129918832832896, "INFANRIX": 3.4374250120919583, "INVEGA": 17.41556131767222, "KEPPRA": 2.7995991065862977, "LACOSAMIDE": 2.1052859502188457, "LATUDA": 12.065524896485076, "LEVETIRACETAM": 2.775534225488941, "LEVODOPA": 56.28044208587159, "LYRICA": 2.511753916043684, "MENVEO": 3.2774674902731102, "MIDAZOLAM": 3.587014186919083, "MISOPROSTOL": 21.520422080572413, "NAGLAZYME": 1.0595657432567032, "NEUPRO": 16.903616598255795, "NIMENRIX": 1.6982582852332069, "OLANZAPINE": 6.049791328036221, "ONGENTYS": 56.53748089743798, "PREGABALIN": 2.751405115170214, "PREVENAR": 2.690482314826129, "RISPERIDONE": 3.3110846549008937, "SIFROL": 12.306324604090507, "STALEVO": 30.289171692590585, "SYCREST": 9.832642160628982, "TAMIFLU": 1.439277907182066, "TASMAR": 28.03310513943156, "VFEND": 1.1158236231958594, "VIMPAT": 2.377223616214762, "XYREM": 1.6531919871015412, "ZYPADHERA": 7.768752914180816, "ZYPREXA": 6.596708984899679, "null": 2.4554988461062046}
\ No newline at end of file
+{"ARIPIPRAZOLE": 18.155021688034243, "ZYPREXA": 4.767504971440186, "null": 4.156050214729344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2635.json
index 83da2b16967..c7722da420e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2635.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2635.json
@@ -1 +1 @@
-{"ABILIFY": 78.76470344929817, "null": 2.461877076965808}
\ No newline at end of file
+{"null": 1.9046738537938133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2636.json
index 9cecd026769..838ad036dcb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2636.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2636.json
@@ -1 +1 @@
-{"null": 1.244470496613888}
\ No newline at end of file
+{"null": 0.466733711871285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2637.json
index 0086a45cdcc..415d998e2e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2637.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2637.json
@@ -1 +1 @@
-{"AVASTIN": 8.456253274498467, "EYLEA": 12.040002848317735, "NEXAVAR": 2.755021144384417, "OPDIVO": 5.147577799946268, "TASIGNA": 6.119056515059161, "ZYPREXA": 2.4759309683808337, "null": 2.4533378158691965}
\ No newline at end of file
+{"BEOVU": 471.1826648627459, "BRAFTOVI": 27.53591418825309, "CASPOFUNGIN": 63.39071887548951, "COMIRNATY": 0.3098405432345618, "EYLEA": 36.38977796609247, "null": 0.4066675587638045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2638.json
index c6530136257..02f600525c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2638.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2638.json
@@ -1 +1 @@
-{"null": 3.499241884108153}
\ No newline at end of file
+{"CICLOSPORIN": 16.587506834595956, "COMIRNATY": 0.3411190263793297, "null": 1.393244021198756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2639.json
index 2f2e1da0faf..e0b7b72a73b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2639.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2639.json
@@ -1 +1 @@
-{"ABACAVIR": 10.37914977592417, "ABILIFY": 40.78053740906228, "AFINITOR": 2.0256709571599485, "AMINOSALICYLIC": 9.76149781482696, "APIXABAN": 1.1056703843901097, "ARAVA": 1.124501695396572, "ARIPIPRAZOLE": 34.64062511994929, "AVANDIA": 1.7825679849095, "BIKTARVY": 4.884081244106118, "BYETTA": 3.5159773124968674, "CICLOSPORIN": 1.451200427327031, "CLOPIDOGREL": 1.5326184053237395, "COMBIVIR": 11.310499689645104, "DARUNAVIR": 9.211546746419312, "EFAVIRENZ": 18.37151561113225, "ENTRESTO": 3.799857783534837, "EPIVIR": 4.8798026076846375, "FASLODEX": 1.2724658197302172, "FORXIGA": 3.6318232571104634, "HUMIRA": 2.332446140839369, "IBUPROFEN": 1.9378196681322624, "IRBESARTAN": 7.435931195961746, "ISENTRESS": 6.097321143873284, "JANUMET": 3.605746382689284, "JANUVIA": 4.769396955951773, "KALETRA": 22.44941901848393, "LOPINAVIR": 77.72601850586496, "METFORMIN": 36.77333980987071, "METHOTREXATE": 2.4361771665827, "NORVIR": 22.02834438013721, "OLANZAPINE": 4.651356975304616, "OMALIZUMAB": 2.05477291599519, "ROACTEMRA": 1.4115456499650103, "SYMTUZA": 89.77957649352986, "TASIGNA": 6.6961612187379895, "TESTOSTERONE": 9.428058377200806, "TRIUMEQ": 9.697881093398912, "ZOSTAVAX": 4.855031760757992, "ZYPREXA": 16.1814252035681}
\ No newline at end of file
+{"null": 0.4335501018639234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/264.json
index d9179b9800a..1958815dcfc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/264.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/264.json
@@ -1 +1 @@
-{"ABILIFY": 58.88661279333641, "ARIPIPRAZOLE": 85.11145305960358, "BRINTELLIX": 5.561918901569084, "CARIPRAZINE": 79.92834982480295, "CIRCADIN": 9.333845112202145, "CYMBALTA": 3.070673060090038, "DULOXETINE": 5.00824402245491, "INVEGA": 12.6583957862369, "LATUDA": 50.277405798980354, "LEVETIRACETAM": 1.6062336059335347, "LURASIDONE": 38.58075478871739, "MELATONIN": 4.804366691540161, "OLANZAPINE": 21.53859848925718, "PROPRANOLOL": 6.113084100920687, "REAGILA": 204.8978556760539, "RISPERIDONE": 5.32539636822857, "SYCREST": 54.24927311229766, "VORTIOXETINE": 18.435545141214945, "ZYPADHERA": 29.23638263451846, "ZYPREXA": 17.46367824396271, "null": 1.826940164636242}
\ No newline at end of file
+{"CELLCEPT": 87.67625859294492, "CICLOSPORIN": 54.9906257986634, "null": 0.2995411749802718}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2640.json
index 40ea72a4368..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2640.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2640.json
@@ -1 +1 @@
-{"COMIRNATY": 10.7953701791866, "COVID19": 1.1224630910764335, "ELLAONE": 4.680213937965393, "ESMYA": 1.2950814460685287, "EVRA": 1.0964050162440218, "GARDASIL": 1.586335299434504, "MAVENCLAD": 1.6317024857748357, "SPIKEVAX": 2.465760366867761, "TOZINAMERAN": 5.367182833756627}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2641.json
index 29960f41233..8dee419307b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2641.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2641.json
@@ -1 +1 @@
-{"IRBESARTAN": 134.92989091020652, "null": 2.832645681281876}
\ No newline at end of file
+{"EYLEA": 35.591800072718335, "null": 2.312540617857054}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2642.json
index 5ab8c3b99fe..f902d87660e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2642.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2642.json
@@ -1 +1 @@
-{"null": 3.5424778899304763}
\ No newline at end of file
+{"TOPOTECAN": 3234.0518187156263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2643.json
index 53584897b84..4a1cb47e1c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2643.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2643.json
@@ -1 +1 @@
-{"COMBIVIR": 8.129044492437178, "KALETRA": 2.923570590488551, "KEPPRA": 4.952809945503441, "LEVETIRACETAM": 6.939375777940857, "METHOTREXATE": 1.60510203555744, "VIMPAT": 6.3371493952647295, "ZYPREXA": 1.1711271238499188, "null": 11.838128282423618}
\ No newline at end of file
+{"null": 4.762674259033188}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2644.json
index 04c15a91776..3d68c90e839 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2644.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2644.json
@@ -1 +1 @@
-{"GARDASIL": 10.603316960373816, "null": 1.969617177308029}
\ No newline at end of file
+{"null": 4.492815936186281}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2645.json
index 09648e75a21..993d3f7e92e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2645.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2645.json
@@ -1 +1 @@
-{"ACLIDINIUM": 5.982304367531809, "ADALIMUMAB": 5.6285399700240974, "ADEMPAS": 3.860989987772288, "ADENURIC": 1.0922388496776292, "AERIUS": 1.3057441417013598, "AIMOVIG": 4.382903780844188, "AMINOSALICYLIC": 5.575246308052946, "APREMILAST": 3.7391949386541614, "APREPITANT": 2.4009209694429616, "APROVEL": 2.176995051876733, "ARAVA": 1.6172736227091988, "ARIPIPRAZOLE": 1.8792420308189983, "AVAMYS": 6.497273792486839, "BEDAQUILINE": 1.6114342975972276, "BETMIGA": 2.592440165742671, "BEVACIZUMAB": 1.1624296894568962, "BIKTARVY": 2.306119251792408, "BONVIVA": 2.550747412218436, "BOSENTAN": 3.4813260356856484, "BOSULIF": 1.400442551477963, "BRINTELLIX": 3.215723570659224, "BUDESONIDE": 6.910705238992231, "BYDUREON": 2.31081558693828, "BYETTA": 2.095497932222972, "CABOMETYX": 1.2491619647748544, "CHAMPIX": 2.070130293549555, "CLOPIDOGREL": 1.818777073143726, "COAPROVEL": 1.0777736180214974, "DAKLINZA": 1.1516800360040356, "DESLORATADINE": 1.7677168325592707, "DIGESTIVES": 15.696342255804302, "DOLUTEGRAVIR": 1.3362041552365187, "DULAGLUTIDE": 2.1982740200428776, "DULOXETINE": 1.3845569485298674, "EDURANT": 3.1275379498560065, "ELLAONE": 1.7816651397125292, "ENTECAVIR": 1.585177598154471, "ENTYVIO": 1.1804343928978227, "EPADERM": 25.38729919319676, "ERENUMAB": 13.2799086976483, "ESBRIET": 6.984396402429972, "ESOMEPRAZOLE": 1.101884874407658, "EUCREAS": 1.4875996775152536, "EXFORGE": 1.129789116352801, "EXJADE": 1.218473987546922, "EXVIERA": 2.8344906864074657, "FASLODEX": 1.248736310480093, "FLUTICASONE": 2.9989504174707724, "FORSTEO": 2.6183927994982232, "FULVESTRANT": 1.323165809035564, "GALAFOLD": 2.408050438087031, "GALVUS": 1.5665430408087884, "GENVOYA": 1.9524011322720416, "GLIBENCLAMIDE": 2.2505005264179623, "HARVONI": 1.0289741291513324, "IBRANCE": 1.3340574601090724, "IMATINIB": 1.0097221077187135, "IMBRUVICA": 2.057980807407374, "INCIVO": 1.001654317510277, "IRINOTECAN": 1.5382373950223558, "JANUMET": 1.951552150113245, "JANUVIA": 1.590457380484133, "KAFTRIO": 1.1104000577227375, "KISQALI": 1.2544145552476649, "LEFLUNOMIDE": 4.0609809584913, "LIRAGLUTIDE": 1.5604209545739185, "LYNPARZA": 1.9144070660721764, "MELATONIN": 1.3490185510470825, "METHOTREXATE": 1.229956864165194, "MICARDIS": 1.1390509522429757, "MIMPARA": 1.3457280503169806, "MOVYMIA": 3.8862109221233063, "OCALIVA": 1.403193466057615, "OFEV": 3.006162773041564, "ONGLYZA": 3.72242112220773, "OPSUMIT": 1.1892936832191026, "OXYBUTYNIN": 1.2135273880552406, "OZEMPIC": 3.266155724098223, "PANTOPRAZOLE": 1.4035377644168827, "PEGASYS": 1.1972533351354948, "PEGINTERFERON": 1.2045322164762722, "PEGINTRON": 1.0870125140996754, "PIRFENIDONE": 2.375431447975917, "PLAVIX": 1.116021832059534, "PRADAXA": 1.2065222697800322, "PREGABALIN": 3.781655993772897, "PROTELOS": 1.368644711306117, "PROTOPIC": 8.132382769483337, "RANEXA": 2.473764833965856, "REVATIO": 1.0158333854103945, "RINVOQ": 1.298276910202382, "RYBELSUS": 8.749753250089785, "SAXENDA": 8.065031145930122, "SEMAGLUTIDE": 4.174230861818576, "SILDENAFIL": 3.1599159678592583, "SUTENT": 3.971632303765347, "TASIGNA": 1.0194572298360347, "TERIPARATIDE": 1.6322436333773385, "TICAGRELOR": 1.147616061207158, "TOVIAZ": 1.7373713629549754, "TRULICITY": 5.444297239718352, "VARENICLINE": 2.020503727977837, "VIAGRA": 1.2261914942050447, "VICTOZA": 3.238683133725344, "VIRAMUNE": 1.611208488649118, "VOTRIENT": 1.0978945745836632, "XALKORI": 2.206614579092871, "XELJANZ": 1.56769531444129, "ZEJULA": 2.361983253494369, "ZEPATIER": 2.0425352548633824, "ZYLLT": 8.012185363188555, "null": 1.2473887352532402}
\ No newline at end of file
+{"BEOVU": 360.2528882273764, "EYLEA": 137.79605809004923, "null": 0.2963378037522961}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2646.json
index 2b1717409fb..473c9b2b7be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2646.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2646.json
@@ -1 +1 @@
-{"ABILIFY": 1.3395836154138872, "ACLIDINIUM": 5.144541199056696, "AERIUS": 1.380109386922281, "AFINITOR": 1.8010106850234195, "ALISKIREN": 17.41312533918719, "ATAZANAVIR": 1.9758616937388909, "ATEZOLIZUMAB": 2.383374202137721, "AUBAGIO": 1.1713214242959125, "AZILECT": 1.7966321869397603, "BARACLUDE": 1.6829390253111554, "BIKTARVY": 4.029437877438168, "BONVIVA": 1.417015113636726, "BRAFTOVI": 1.4756408726337145, "BRINTELLIX": 1.4329311154291158, "CAPECITABINE": 1.0064630269527373, "CARBIDOPA": 1.0679641431017302, "CELLCEPT": 1.0860846049405466, "CELSENTRI": 2.249869611395156, "COMTAN": 15.53734763872584, "COTELLIC": 1.1264687013341343, "CRESEMBA": 2.064852560599768, "CRIXIVAN": 2.071832252934344, "CYMBALTA": 1.1967599517905434, "DABRAFENIB": 2.5750605699166345, "DARUNAVIR": 1.632700539887057, "DESCOVY": 2.155240590810111, "DOCETAXEL": 1.1379186496213278, "DOXORUBICIN": 1.416274286015229, "EBIXA": 1.898845361653253, "ELIQUIS": 1.894761852306958, "EMEND": 4.705210760438708, "ENFUVIRTIDE": 9.334210902213693, "ENTACAPONE": 6.151914750372951, "ENTRESTO": 1.6982292499673726, "ENVARSUS": 8.96625979299257, "EPCLUSA": 1.9118343483913507, "ERLEADA": 3.2847993241693287, "EUCREAS": 2.4359430013814727, "EXFORGE": 1.1675802292534927, "FAMPYRA": 1.6161336742679049, "FIRDAPSE": 3.64168044297242, "FLUTICASONE": 1.7029881611732665, "GALVUS": 2.18326425019801, "GENVOYA": 1.641047002626192, "HARVONI": 1.0322418610263782, "IBRANCE": 1.5986801053997215, "INCRUSE": 1.142261162228518, "INLYTA": 1.241133055773793, "INVEGA": 1.304328140125116, "IRESSA": 1.0591416825553472, "ISENTRESS": 5.4722149076176, "JAKAVI": 2.1876368523414564, "JANUMET": 6.257790160595537, "JANUVIA": 3.409930239771515, "JORVEZA": 8.012679659514697, "KALETRA": 1.2593532347361327, "KEPPRA": 1.6330061653046606, "KISQALI": 1.6264478233469315, "KYMRIAH": 1.0481196474183907, "LATUDA": 1.556720411845363, "LEVODOPA": 2.202798262390475, "LYNPARZA": 1.814052631181341, "MEKINIST": 2.48122294134146, "MELATONIN": 1.6319994755128917, "MEMANTINE": 2.5070819687613435, "METFORMIN": 1.8897299916799863, "MICARDIS": 1.032219672106374, "MIMPARA": 10.24079618002619, "NEXAVAR": 1.1081188397967945, "NORVIR": 1.1460133987321413, "NOVONORM": 1.5804213105734042, "NOXAFIL": 1.421131629051319, "OCEAN": 14.487076422584666, "OCRELIZUMAB": 1.7351341325732803, "OFEV": 1.0712465066199046, "OLANZAPINE": 1.5566216852240455, "ONGLYZA": 1.39817100879775, "OXYBUTYNIN": 2.2418088049038927, "PACLITAXEL": 1.823145155598925, "PEGINTERFERON": 1.187311125466146, "PEGINTRON": 1.0812242584969969, "PEMBROLIZUMAB": 1.4916989926396889, "PROTELOS": 2.206685222059099, "PROTOPIC": 6.867196944186953, "RADIATION": 6.5225254836408695, "RANEXA": 1.9547609304060896, "RANOLAZINE": 1.0977551008725546, "RASILEZ": 2.4838974968758816, "RELVAR": 1.0384995105378527, "REMICADE": 1.165936959086842, "REYATAZ": 2.4733034096747586, "RILUTEK": 10.107918984872065, "RISPERIDONE": 1.4782605260228077, "RIXATHON": 3.24763391179389, "RYDAPT": 4.109702489882915, "SAQUINAVIR": 25.71960913371485, "SOLIRIS": 1.636986297007544, "SPINRAZA": 3.8667067467362215, "STALEVO": 20.125659654680128, "SUTENT": 1.7933330969999708, "SYCREST": 3.72985930246459, "TAFINLAR": 5.337199756249735, "TAGRISSO": 1.7449753403158037, "TASIGNA": 1.24398933978578, "TEMODAL": 3.610513347028712, "TIVICAY": 1.321622285911627, "TOVIAZ": 2.696459266231248, "TOZINAMERAN": 1.033897219846792, "VEMLIDY": 8.147846033925518, "VENCLYXTO": 1.6570648362743727, "VENETOCLAX": 2.0152991192318424, "VIMPAT": 1.7082287812902253, "VOTRIENT": 1.206125688138402, "XALKORI": 2.721957920702261, "XELODA": 1.9517341842364369, "XOLAIR": 1.2037428666185273, "XTANDI": 6.667219705365622, "YESCARTA": 1.1467389126552865, "ZAVESCA": 9.080036573708147, "ZELBORAF": 3.2535979407698523, "ZEPATIER": 2.359828298224959, "ZYPREXA": 1.9281442262193773, "null": 1.627003248442468}
\ No newline at end of file
+{"MYCOPHENOLATE": 207.8826678735093, "null": 0.6201642149798156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2647.json
index 79320029612..661e955f736 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2647.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2647.json
@@ -1 +1 @@
-{"ABACAVIR": 1.942834603829827, "CHAMPIX": 3.146561454865356, "CYMBALTA": 2.8788059796859886, "FENTANYL": 2.8303114303977708, "KEPPRA": 5.51746363042228, "LATUDA": 5.721153603028377, "LYRICA": 3.003205078725949, "OLANZAPINE": 2.918834384814183, "TOZINAMERAN": 1.244365929039683, "ZYPREXA": 3.370030340456351, "null": 2.2266635461189845}
\ No newline at end of file
+{"COMIRNATY": 0.2105807179913225, "VFEND": 151.94192232343244, "VIAGRA": 38.11186535611529, "VORICONAZOLE": 31.27365558416451, "null": 1.0104040901693632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2648.json
index 625cb52c849..90456cbc5a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2648.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2648.json
@@ -1 +1 @@
-{"AFINITOR": 1.343329863153199, "ANORO": 2.4295926644206123, "AVASTIN": 1.1949301153491407, "AVELUMAB": 12.464257655064747, "AXITINIB": 13.71902139933939, "AZILECT": 3.058425191190832, "BAVENCIO": 11.912090996202645, "BENLYSTA": 1.55274386985017, "BEVACIZUMAB": 1.2643960899007332, "BOTULINUM": 33.19621117652444, "BUDESONIDE": 4.344311172158866, "BYDUREON": 1.1461229722338309, "CABOMETYX": 6.049590560859276, "CHOLESTAGEL": 18.24035849344978, "COMTAN": 1.011349251045755, "DUORESP": 15.472144797166589, "ENOXAPARIN": 1.5913010340206737, "ENTACAPONE": 2.1097123571783083, "EVEROLIMUS": 1.5887622482867172, "FASENRA": 3.427029109676699, "FIRDAPSE": 1.9228392899448843, "FLUTICASONE": 1.2864128040759064, "FOTIVDA": 16.328775921289758, "IBRANCE": 1.1629340077071986, "INCRUSE": 5.983139677246797, "INLYTA": 16.57617538578399, "IRBESARTAN": 1.5966819264728245, "KEYTRUDA": 4.051278935993192, "LAMIRA": 19.474822639182825, "LENVIMA": 7.856109076067763, "LEVOFLOXACIN": 1.1938427707486612, "LONSURF": 2.201331234690422, "MEPOLIZUMAB": 2.273216850496192, "NEXAVAR": 6.287836771291168, "NUCALA": 2.078571297234622, "OFEV": 1.260289343151411, "OMALIZUMAB": 2.5908484895114263, "ONCASPAR": 1.1215170830875498, "QUTENZA": 1.8084654233995592, "REGORAFENIB": 5.548416506217792, "RELVAR": 33.792573790431014, "REVINTY": 53.26779905974566, "RIXATHON": 3.551249212173429, "RUCONEST": 1.4992395666993823, "STIVARGA": 14.28653368540536, "SUTENT": 1.2894805000650442, "TELMISARTAN": 1.5246318227808016, "TESTOSTERONE": 1.4296401734537425, "TOVIAZ": 2.247012548641629, "TRELEGY": 9.226007027080628, "UMECLIDINIUM": 4.420932041634387, "VOTRIENT": 1.952788707910189, "XELJANZ": 1.2627060025195098, "XOLAIR": 2.6851119115028546, "null": 1.6857370056744128}
\ No newline at end of file
+{"AFINITOR": 0.8121415561024613, "ALEMTUZUMAB": 0.8135911727420161, "ARAVA": 0.1636532572451428, "ARIXTRA": 11.441608480541724, "ATRIPLA": 0.0526075675009318, "AUBAGIO": 1.1387127572247815, "AVANDIA": 0.7202217934635415, "AVASTIN": 0.524251402301552, "BETAFERON": 1.45296181599775, "BIKTARVY": 1.2278255462958765, "BRILIQUE": 0.9482994983387236, "BUPRENORPHINE": 0.6720279393646618, "BYETTA": 0.4568227180460059, "CAPECITABINE": 0.776344028102184, "CHAMPIX": 0.4818515529963547, "CICLOSPORIN": 0.7008395676105423, "CLOPIDOGREL": 1.2998129931126627, "COMBIVIR": 1.4404374073586206, "COMIRNATY": 0.1793753390163163, "COMTAN": 15.02122212759018, "COSENTYX": 0.3947671856463378, "CYMBALTA": 1.010788530433133, "CYTARABINE": 0.4012940350990179, "DEXAMETHASONE": 0.2810052908545168, "ELIQUIS": 1.5296878444205146, "ENOXAPARIN": 1.1881174647893369, "ENTACAPONE": 10.166329997854277, "ENTRESTO": 0.4436961294661647, "ESBRIET": 1.2785433905075418, "EUCREAS": 4.015750077957812, "EXFORGE": 1.8069422790799328, "EXJADE": 4.765211081937268, "EXVIERA": 3.0008808850100834, "FASLODEX": 0.9246689888502032, "FENTANYL": 0.4599111847643419, "FORSTEO": 0.7029397852840066, "FORXIGA": 1.505970133211919, "GALVUS": 2.937058308108096, "GARDASIL": 0.1966989983502016, "HIZENTRA": 0.7155038169307774, "HUMAN": 1.193701514910999, "IBRANCE": 0.3684504086478565, "IBUPROFEN": 1.6056710723068424, "INLYTA": 0.9486585271354788, "INSULIN": 0.4699009136938462, "IPILIMUMAB": 0.8683781322037166, "IRBESARTAN": 1.8693204861536643, "JAKAVI": 0.6176345964627181, "JANUVIA": 1.0620509039793595, "JARDIANCE": 0.8683913797740644, "KAFTRIO": 2.059914384632265, "KALETRA": 0.7692371018508333, "KETEK": 14.048979455581048, "KEYTRUDA": 0.3787960246179851, "KISQALI": 1.3846720477469627, "LANTUS": 0.1837391542530618, "LEMTRADA": 1.7407329216776208, "LEVOFLOXACIN": 1.0668811080123588, "LIXIANA": 3.146456318444303, "LONSURF": 4.276619544596277, "LYRICA": 0.5952900700965845, "MEKINIST": 1.3180279885298651, "METHOTREXATE": 0.4534895809695901, "MICARDIS": 2.0803883930497644, "MULTAQ": 3.3400013365444763, "NEVANAC": 8.273675765276668, "NEXAVAR": 0.9000012899026355, "OCALIVA": 5.281365597074943, "OPDIVO": 0.697039134105668, "OPSUMIT": 0.4386689059877675, "PEGASYS": 1.8450625252685888, "PEGINTRON": 1.4017803424500066, "PLAVIX": 1.3435003579740892, "PREGABALIN": 0.903055452538827, "PRIVIGEN": 2.6218448434477493, "RANEXA": 14.44729951282272, "RANOLAZINE": 7.140668111941144, "RASBURICASE": 25.7463132108657, "RIBAVIRIN": 1.2162359695759113, "RINVOQ": 0.5752693048148266, "SAXENDA": 0.8724923563832544, "SHINGRIX": 0.3594791048056903, "SIFROL": 2.81198359050999, "SOLIRIS": 13.039199139140528, "SPIKEVAX": 0.3775008965404301, "STALEVO": 20.417729351749163, "STIVARGA": 3.289256791702419, "SUBOXONE": 0.9742211123098828, "SUTENT": 3.326086694609291, "TAMIFLU": 5.318184432389533, "TASIGNA": 1.3485666231755895, "TOVIAZ": 1.4857624759264851, "TOZINAMERAN": 0.3237941647164611, "TRACLEER": 1.3850727076946838, "TRIUMEQ": 2.6363422670054346, "TRULICITY": 0.9598211089107668, "TRUVADA": 0.1996254009258215, "TWINRIX": 2.3549682693385887, "VAXZEVRIA": 0.2689975121898166, "VFEND": 0.6045130098383152, "VIAGRA": 0.5545120442130351, "VIMPAT": 0.9367955086762332, "VOTRIENT": 1.587463128276142, "XARELTO": 1.6661899677072214, "XELJANZ": 0.5789308723763505, "XTANDI": 1.045931451524202, "ZOSTAVAX": 0.2554819628423026, "ZYPREXA": 0.6323131018826761, "null": 2.169030730190248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2649.json
index 8c3f9aee96b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2649.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2649.json
@@ -1 +1 @@
-{"ARAVA": 2.379511087341074, "CHAMPIX": 1.6913269310803978, "CYMBALTA": 127.10192585752402, "ISENTRESS": 8.71449070251109, "LEVETIRACETAM": 1.2885716956854538, "LEVODOPA": 9.14877389115202, "LEVOFLOXACIN": 2.072709770882443, "OLANZAPINE": 2.817686011247777, "VFEND": 9.36907865211444, "VORICONAZOLE": 3.042502860717484}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/265.json
index 81f432f8e0d..9142ecb898f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/265.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/265.json
@@ -1 +1 @@
-{"CARBIDOPA": 37.022900387103135, "CLOPIDOGREL": 2.2360412093580933, "COMTAN": 135.48880027440038, "ENTACAPONE": 90.16038367664906, "ENTRESTO": 4.05736747784321, "IBUPROFEN": 3.973665210715577, "KEPPRA": 1.6205146784134112, "LANTUS": 1.6938422827518431, "LEVODOPA": 72.04836978935596, "OLANZAPINE": 6.136929522745733, "STALEVO": 60.21426549310371, "ZYPREXA": 2.704758957505391, "null": 2.399516099169364}
\ No newline at end of file
+{"CICLOSPORIN": 29.131268708411568, "DEXAMETHASONE": 33.79675965304617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2650.json
index 328dcd80130..5c82226f7cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2650.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2650.json
@@ -1 +1 @@
-{"GARDASIL": 7.573681381639845, "STELARA": 6.553030304113835}
\ No newline at end of file
+{"null": 1.3183930208231711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2651.json
index bd97d73c6e8..6f67beeb341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2651.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2651.json
@@ -1 +1 @@
-{"1": 3.549147030514927, "ACCOFIL": 1.2466389400854492, "ACETAMINOPHEN": 1.7276236660647593, "ACLIDINIUM": 2.214707649877924, "ADCIRCA": 1.939310346188537, "ADEMPAS": 2.459017132234253, "AERIUS": 1.228497565905584, "AFINITOR": 1.7294027315381346, "AGENERASE": 1.061033745587084, "AKYNZEO": 1.5879813857387926, "ALENDRONATE": 1.83031292549502, "ALOXI": 1.0774437344776888, "AMBRISENTAN": 2.7037390777486, "AMLODIPINE": 3.196263937907502, "ANORO": 3.6687668112659177, "ANTIBIOTICS": 1.0415358444529308, "APIXABAN": 2.6565508940948543, "APREPITANT": 2.645207755199389, "ARZERRA": 1.7418507956132612, "AVAMYS": 2.751217065736715, "AVANDIA": 1.2314622194850402, "AZOPT": 2.551894340827068, "BEDAQUILINE": 2.223247686968735, "BEMFOLA": 2.2847065573708543, "BENRALIZUMAB": 4.9567023384589, "BEVESPI": 3.972088226332475, "BINOCRIT": 1.0292173938440603, "BIRESP": 7.955694403386494, "BOSENTAN": 1.6539362271536775, "BOSUTINIB": 1.045984675993317, "BREXPIPRAZOLE": 1.227087394264898, "BRIDION": 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2.085164273528345, "RELVAR": 2.9640114966299103, "REPATHA": 1.0851639059327385, "REVATIO": 2.8971308387304293, "REVINTY": 2.112429277585292, "RILUTEK": 1.0683025566017303, "RIVAROXABAN": 1.611533335932345, "RIXATHON": 2.813128663126992, "SEEBRI": 2.839411147836903, "SILDENAFIL": 1.867173216797941, "SPIKEVAX": 1.0077966986490132, "SPRYCEL": 1.4779868017571232, "SUGAMMADEX": 1.4657887536405187, "SYNAGIS": 1.2467535938865708, "TAFAMIDIS": 2.0852597649905174, "TELMISARTAN": 1.3492918828672669, "TEMSIROLIMUS": 1.0061915311676135, "TICAGRELOR": 4.729598761683767, "TIKOSYN": 1.0753087304222766, "TOBI": 4.937798022050716, "TORISEL": 1.8482428457012048, "TOZINAMERAN": 1.5248262843923537, "TRACLEER": 2.893974703636085, "TRACTOCILE": 2.9025549773361257, "TRELEGY": 4.870883233537683, "ULTIBRO": 2.918677390545869, "UMECLIDINIUM": 4.57563122893999, "UPTRAVI": 1.537291741818137, "UROREC": 1.6985255054278554, "VALSARTAN": 1.4748558939511285, "VARENICLINE": 1.1928932870764748, "VELTASSA": 1.0914157678624457, "XOLAIR": 2.9302373032031803, "ZARZIO": 1.7314616269478882, "ZIAGEN": 1.8096597761732265, "ZIDOVUDINE": 1.1697819551830415, "ZYLLT": 1.368673762476652, "null": 1.2076040787728315}
\ No newline at end of file
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2652.json
index 83bbddb04f5..4829f014413 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2652.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2652.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 5.174267971881172, "BEDAQUILINE": 19.973183170338768, "BRILIQUE": 57.47154940628745, "CLOPIDOGREL": 3.450205573618499, "ENTRESTO": 6.922070749485373, "JANUMET": 4.1818935395969, "OMALIZUMAB": 7.884223483013757, "OPSUMIT": 9.182742724084338, "PANTOPRAZOLE": 7.485024691876232, "SPIRONOLACTONE": 14.069321519260678, "TICAGRELOR": 16.622340433961543, "XOLAIR": 1.4700482620496818}
\ No newline at end of file
+{"AZATHIOPRINE": 23.00445645455145, "BASILIXIMAB": 304.555245457088, "CELLCEPT": 38.37864990922531, "CICLOSPORIN": 97.78482414149823, "MYCOPHENOLATE": 80.89388865194267, "null": 0.5654538867725605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2653.json
index 11887a5955e..a3eeca4c482 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2653.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2653.json
@@ -1 +1 @@
-{"ABRAXANE": 3.8190710535249415, "ACLIDINIUM": 11.156041974721877, "ADCIRCA": 7.401277973368491, "ADEMPAS": 12.824523977657682, "AFINITOR": 1.9418379624220703, "AMBRISENTAN": 7.761725619343239, "AMIKACIN": 1.2910307599249866, "ANORO": 2.2340183646842786, "APIXABAN": 6.65119772559568, "AVAMYS": 14.882810343737576, "AVANDIA": 1.6085710227567134, "BEDAQUILINE": 1.6656384948957792, "BENRALIZUMAB": 2.163396984369974, "BINOCRIT": 5.943574659825215, "BOSULIF": 1.518709732853495, "BRILIQUE": 7.623489393582469, "BUDESONIDE": 2.104296114538529, "CHOLESTAGEL": 22.79024278950676, "CLOPIDOGREL": 1.2733370628400216, "COMIRNATY": 1.408899450343967, "DAPAGLIFLOZIN": 3.0759632911647574, "DASATINIB": 4.38142812326102, "DELAMANID": 4.268086469977132, "EMPAGLIFLOZIN": 1.041691282208756, "ENTRESTO": 2.944505933026446, "ESBRIET": 3.68963994656675, "ESOMEPRAZOLE": 1.9221650650309492, "FASENRA": 1.7958554630891164, "FASLODEX": 1.975744943308145, "FLUTICASONE": 14.232755675170752, "FULVESTRANT": 1.2718860709412247, "GLIVEC": 2.1223782339139228, "HERCEPTIN": 1.1088273384716971, "HUMIRA": 1.3422924200149418, "IBRANCE": 1.5269759359824906, "INCIVO": 1.5600515375894457, "INCRUSE": 2.135537577371595, "INSULIN": 3.236672286225232, "ISENTRESS": 1.3830968899952825, "IVABRADINE": 4.994070997371184, "JAKAVI": 1.380394066926111, "KYPROLIS": 1.141992122295469, "LAMIVUDINE": 1.9149333102352537, "LIRAGLUTIDE": 2.656328935660811, "LIXIANA": 1.1696575757004308, "LYNPARZA": 1.1032368335562193, "MEPOLIZUMAB": 12.665602138356224, "MULTAQ": 3.020335282606203, "MYCOPHENOLATE": 1.3931800415858355, "NILOTINIB": 1.9279834032758487, "NOT": 1.0823396206523512, "NUCALA": 6.0232642095907, "OFEV": 8.314153551343185, "OLAPARIB": 2.6853782465150915, "OMALIZUMAB": 5.341831501654936, "OPSUMIT": 9.887235955672486, "PANTOPRAZOLE": 3.900207705920399, "PEGASYS": 1.464736601119896, "PEGINTERFERON": 1.472614063767351, "PEMBROLIZUMAB": 1.124396971767297, "RASILEZ": 1.0982398487533969, "RELVAR": 1.6113776632104393, "REVATIO": 3.331870850676523, "RIBAVIRIN": 1.798490786634838, "RINVOQ": 1.119832947982224, "RIOCIGUAT": 40.80273422367407, "RITUXIMAB": 1.329730424327624, "RIVAROXABAN": 3.12858777321857, "RUBRACA": 1.1402046270564368, "SEEBRI": 14.482065994242468, "SILDENAFIL": 4.203366135241993, "SOLIRIS": 1.3135203846347725, "SPIRONOLACTONE": 1.8176658413826223, "SPRYCEL": 2.163196769848902, "TAGRISSO": 1.4129764985187014, "TASIGNA": 1.3833117656632288, "TICAGRELOR": 1.6137610653037544, "TORISEL": 1.5909524017553027, "TRACLEER": 4.141406100953541, "TRELEGY": 3.556854458016285, "UMECLIDINIUM": 9.44955322653682, "VALSARTAN": 1.7680368198317202, "VOTRIENT": 1.023022239160984, "XARELTO": 1.14899939181857, "XOLAIR": 2.1145989537354444}
\ No newline at end of file
+{"BENLYSTA": 25.003281218748143, "COMIRNATY": 0.4413163236671186, "HUMIRA": 21.323570868089508, "null": 1.02984716834072}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2654.json
index 91820ff17f7..79941d8462d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2654.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2654.json
@@ -1 +1 @@
-{"AVANDIA": 8.603117149973123, "BRILIQUE": 31.657439989325244, "ENTRESTO": 19.07967881430109, "null": 1.200705472746912}
\ No newline at end of file
+{"COSENTYX": 23.989746821421907, "STELARA": 21.392542805373704, "null": 0.3511171371258133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2655.json
index d8503c161dd..30849b71f0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2655.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2655.json
@@ -1 +1 @@
-{"AVAMYS": 12.6253792159631, "null": 4.620967182930328}
\ No newline at end of file
+{"COMIRNATY": 4.648547290140723, "ESOMEPRAZOLE": 4.435231080521956, "GARDASIL": 16.984119810590094, "IXIARO": 54.86872942512818, "PEGASYS": 0.5070970669127365, "SPIKEVAX": 1.8984256693425483, "TOZINAMERAN": 2.818251216715979, "TWINRIX": 13.039041357385424, "VAXZEVRIA": 1.555723311027125, "null": 0.2259099103245222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2656.json
index ec81a9d1197..af41f1a5464 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2656.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2656.json
@@ -1 +1 @@
-{"null": 1.9362985909516484}
\ No newline at end of file
+{"BYETTA": 3.4449357244123275, "CLOPIDOGREL": 17.029143953551646, "COMIRNATY": 0.2429326638255755, "ELIQUIS": 0.9171137375383148, "GARDASIL": 1.0562793397355523, "HUMALOG": 1.708110321442358, "IPILIMUMAB": 8.301569175555496, "JANUMET": 8.12594858174351, "JANUVIA": 5.026518104156921, "KEYTRUDA": 2.1284898644016685, "NEXAVAR": 1.608843979105173, "OPDIVO": 3.407306997076868, "PLAVIX": 4.164990879415005, "TICAGRELOR": 48.18818488575063, "null": 1.2162472224304015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2657.json
index 15a1f8bedf4..cf9f2c12c7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2657.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2657.json
@@ -1 +1 @@
-{"ABILIFY": 1.7671519385676553, "ADCIRCA": 2.4255694829677807, "AIMOVIG": 1.070960821053295, "ARIPIPRAZOLE": 1.832980071651007, "ATRIPLA": 3.244647847573258, "AUBAGIO": 2.5927521288519326, "AZILECT": 7.9863613490555805, "COMTAN": 2.46547744618903, "COSENTYX": 1.6136224064090912, "DULOXETINE": 3.626742721258669, "ENBREL": 1.0004478658284257, "ENTRESTO": 1.4223804740325003, "EXFORGE": 2.0678397476042383, "FAMPRIDINE": 7.656753256853584, "FAMPYRA": 7.538650716393929, "FASENRA": 1.2203666395510866, "FASLODEX": 2.1005444086792786, "FESOTERODINE": 16.552969929075235, "FORSTEO": 3.092741874930284, "GARDASIL": 2.2114067362863983, "HUMALOG": 1.3397659358357514, "IBRANCE": 1.524674781450722, "INLYTA": 1.0633172170479115, "KEPPRA": 1.147343814324161, "KEYTRUDA": 1.0905063211881365, "KISQALI": 1.3277801354976095, "LEFLUNOMIDE": 2.7147257995655925, "LEMTRADA": 1.110761787860382, "LYRICA": 2.3210063504680405, "MEPOLIZUMAB": 1.9086199227850824, "MICARDIS": 1.8906016064416429, "NOT": 2.2321176366612145, "OPTIMARK": 4.655357901249502, "PLEGRIDY": 1.4492381695502414, "SHINGRIX": 1.9380608966768595, "STALEVO": 5.676051046422579, "STRIBILD": 4.08371184445533, "SUTENT": 1.5120825122457269, "TOVIAZ": 2.283923815862176, "TOZINAMERAN": 2.057555874985428, "TRULICITY": 1.192916565809877, "TRUVADA": 2.3740295489725467, "VIMPAT": 1.3849018232476709, "VIREAD": 1.7961522406542167, "XELJANZ": 2.1322661613748064, "XTANDI": 2.0243222908186453, "ZYPADHERA": 4.683869315360095, "null": 1.0487293545642578}
\ No newline at end of file
+{"AZATHIOPRINE": 92.53506594632752, "null": 1.0783990828868644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2658.json
index 070023f93f0..7882eab5886 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2658.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2658.json
@@ -1 +1 @@
-{"ABILIFY": 39.17464153176729, "ARIPIPRAZOLE": 20.93701941470701, "BRINTELLIX": 1.3635980000159238, "BRIVARACETAM": 7.855907506312775, "BUPRENORPHINE": 1.277247053783512, "CARBIDOPA": 14.559868830160468, "CARIPRAZINE": 45.30758212232775, "COMTAN": 6.988147821292804, "CYMBALTA": 1.7776193493797765, "DEXAMETHASONE": 1.700789911785197, "DULOXETINE": 4.372915530196339, "ENTACAPONE": 30.165469395079832, "FENTANYL": 1.3911252733589798, "INVEGA": 18.64753383363957, "KEPPRA": 2.14858851614556, "LATUDA": 43.07225106585189, "LEVETIRACETAM": 1.7286428211782985, "LEVODOPA": 14.121036460241662, "MIDAZOLAM": 7.298356964346864, "OLANZAPINE": 16.799632656291084, "RISPERIDONE": 11.700979329501202, "SIFROL": 5.454671926522068, "STALEVO": 10.376329680771184, "SYCREST": 11.28204736198916, "TAMIFLU": 1.4418498186656343, "ZYPADHERA": 4.480892946158898, "ZYPREXA": 13.317688292937348, "null": 2.677968138049039}
\ No newline at end of file
+{"ABATACEPT": 1.049399916733525, "ALEMTUZUMAB": 23.536713361596025, "ASPARAGINASE": 13.37380877133634, "AZACITIDINE": 12.588829711661024, "AZATHIOPRINE": 21.572221906986115, "BUSILVEX": 92.25667860801164, "BUSULFAN": 170.5346021303958, "CICLOSPORIN": 141.11481262330693, "CYTARABINE": 4.380936863763312, "DEXAMETHASONE": 2.186108153613274, "IMATINIB": 56.00922460109511, "JAKAVI": 7.724895238447313, "MELPHALAN": 29.982214913207343, "METHOTREXATE": 5.659895078232671, "MYCOPHENOLATE": 25.5321948162184, "RUXOLITINIB": 29.79428541269381, "THIOTEPA": 39.84050064061359, "null": 0.3682535808551328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2659.json
index 3b1da85d373..25c6eb2add4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2659.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2659.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 87.28133091259639}
\ No newline at end of file
+{"null": 0.8325331525086475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/266.json
index 1b7c6a628e9..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/266.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/266.json
@@ -1 +1 @@
-{"null": 1.00826282472859}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2660.json
index f396008c645..98302f4e9a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2660.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2660.json
@@ -1 +1 @@
-{"ALDARA": 4.322488389978663, "ANORO": 2.443610979932404, "BENLYSTA": 2.4623047555874487, "BETMIGA": 14.081119804603617, "BINOCRIT": 6.802686601984546, "BRINTELLIX": 1.85391986582306, "BUPIVACAINE": 2.759067571221247, "BUSULFAN": 1.0861565309575385, "CELLCEPT": 1.3350527039399749, "CICLOSPORIN": 1.345785092539609, "CLOPIDOGREL": 1.8646408634480465, "COSENTYX": 1.528295526006919, "CRIXIVAN": 2.561658384609569, "CYMBALTA": 1.683950289426953, "DENOSUMAB": 6.929501558249445, "DULOXETINE": 1.0601217064308588, "ELIQUIS": 1.1458531016651583, "EMPAGLIFLOZIN": 4.041370388861208, "ERLEADA": 1.2835528571456625, "ESOMEPRAZOLE": 1.109996127779892, "EXFORGE": 1.7888007450676349, "EXJADE": 1.3131859245638224, "FASLODEX": 1.4134113403394428, "FORSTEO": 1.1934109282126515, "FORXIGA": 11.393662912467086, "GARDASIL": 2.680385824809301, "HIZENTRA": 1.0765236420869742, "HYDROCORTISONE": 3.5569242428419865, "IBUPROFEN": 1.3228752452939836, "ICLUSIG": 1.189068893267568, "INCRUSE": 3.537017732191505, "INVEGA": 10.765802833813297, "IRESSA": 1.138343681730963, "JANUMET": 1.379126710373023, "JARDIANCE": 12.021156007378602, "JEVTANA": 1.1687778690334187, "LATUDA": 1.258364570746061, "LYRICA": 1.7234118852817362, "MICARDIS": 1.638475323210673, "MIRABEGRON": 12.844730137379438, "NOT": 1.919382131887068, "OCRELIZUMAB": 4.783148104567157, "OLYSIO": 1.3339558790144628, "OXYBUTYNIN": 4.433828689259756, "PEGASYS": 1.5646643027017724, "PROLIA": 6.945468874700508, "RANEXA": 2.742075923854959, "RASILEZ": 1.272255262255908, "RELVAR": 1.062737974734797, "SPIRONOLACTONE": 3.1585164248025936, "SUBOXONE": 1.79682944212537, "SUTENT": 1.3113495271053246, "TIVICAY": 3.0409831746805933, "TOVIAZ": 27.516202212383007, "TRELEGY": 4.93417477080913, "VIAGRA": 5.3868097707135405, "XELJANZ": 1.067667770202204, "XTANDI": 1.78394543845614, "ZOSTAVAX": 1.5102667509258354, "ZYPREXA": 1.6191082030749344, "null": 1.5914047285586357}
\ No newline at end of file
+{"BUSULFAN": 138.30603592823593, "CICLOSPORIN": 94.73591237824442}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2661.json
index d1001dd86c2..62cd9192abd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2661.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2661.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 24.65973361642249, "IVABRADINE": 1124.7900986023074, "null": 1.6735037061125786}
\ No newline at end of file
+{"ALEMTUZUMAB": 57.3642802435685, "BUSULFAN": 107.2665386797747, "CICLOSPORIN": 123.1395294312646, "null": 0.202911879821699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2662.json
index 726d096ff0c..0c9775254b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2662.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2662.json
@@ -1 +1 @@
-{"ERLOTINIB": 907.5501128216642, "GEFITINIB": 3703.5645799823487, "IRESSA": 107.23376182237224, "OSIMERTINIB": 812.9786154550924, "TAGRISSO": 44.62231329418593}
\ No newline at end of file
+{"null": 0.7743032315660294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2663.json
index b5c1f2b5459..6011174afc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2663.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2663.json
@@ -1 +1 @@
-{"null": 1.5160708865908477}
\ No newline at end of file
+{"ALEMTUZUMAB": 83.58065674662686, "BUSULFAN": 138.56206796679737, "CICLOSPORIN": 108.16987867962553, "MYCOPHENOLATE": 30.61991320903457, "THIOTEPA": 192.51735717586604, "null": 0.2636473995806578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2664.json
index e2fcf8a2fbb..ef01f18a643 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2664.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2664.json
@@ -1 +1 @@
-{"APIXABAN": 9.488474184970617, "ELIQUIS": 2.247412164230413, "OMALIZUMAB": 13.276737289082073, "TOZINAMERAN": 2.7542527040907827}
\ No newline at end of file
+{"CICLOSPORIN": 27.254107142948115, "null": 0.5639274422831586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2665.json
index e08111e52df..9654370211c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2665.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2665.json
@@ -1 +1 @@
-{"ADEMPAS": 3.972356740289452, "COMIRNATY": 2.688286132300856, "COSENTYX": 1.023461960047856, "EXFORGE": 1.0279145829867138, "GARDASIL": 1.698147070761812, "MEPOLIZUMAB": 1.6051132320348354, "MICARDIS": 1.308415221097266, "OMALIZUMAB": 2.828427380011585, "SPIKEVAX": 1.6858352151082387, "TOZINAMERAN": 3.344943388244186, "VAXZEVRIA": 1.4159091995860802, "VIAGRA": 1.8813600230181915, "ZOSTAVAX": 1.3562198456330232}
\ No newline at end of file
+{"PEGASYS": 8.225071437874885, "null": 0.9798305125214594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2666.json
index 136bd9c70aa..0907197cd89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2666.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2666.json
@@ -1 +1 @@
-{"COSENTYX": 4.05748409752101, "ELIQUIS": 1.6905853823826191, "EXJADE": 1.9306078470431036, "FORSTEO": 1.8388930401302863, "HUMALOG": 1.846375740037793, "IBRANCE": 1.5605857123830271, "KEPPRA": 1.019111197616719, "LANTUS": 1.2867825092575649, "MEPOLIZUMAB": 5.352281985808756, "NUCALA": 2.4052074984885774, "PEGINTRON": 1.397442304479002, "TOZINAMERAN": 2.2504820504513874, "XELJANZ": 2.5114218597751305, "ZOSTAVAX": 3.2103347400128683, "null": 1.9173143679738132}
\ No newline at end of file
+{"CICLOSPORIN": 5.607857555491381, "null": 2.3997258181004857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2667.json
index ab234c36ede..a06c68540c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2667.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2667.json
@@ -1 +1 @@
-{"BRILIQUE": 14.26053084719862, "CLOPIDOGREL": 2.8458389050122754, "ELIQUIS": 12.704485505650254, "PEGASYS": 1.662631314555025, "PLAVIX": 9.300917612588314, "XARELTO": 12.908940136082927, "null": 1.260396603802644}
\ No newline at end of file
+{"TENOFOVIR": 389.0990288891209, "null": 0.4871327131530268}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2668.json
index 0b6930b53bb..e0a1894f2c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2668.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2668.json
@@ -1 +1 @@
-{"ABATACEPT": 4.468821374598521, "ACETYLSALICYLIC": 109.60648405525048, "ADALIMUMAB": 4.58662260258917, "ARAVA": 1.1563411699462602, "AUBAGIO": 1.2976258200139146, "AVAMYS": 1.0769692942775748, "BENLYSTA": 3.191072336130972, "CIMZIA": 2.275784953666424, "COSENTYX": 2.9954445257016973, "ENTYVIO": 3.068968007253585, "EVISTA": 1.9436197972872584, "EXJADE": 1.4227765670135557, "HIZENTRA": 9.069595599427752, "HUMAN": 3.5547058331081307, "HUMIRA": 1.000632547937373, "HYDROCORTISONE": 2.8365113084518776, "IBRANCE": 1.065134467337687, "INFANRIX": 4.699601217103091, "KEPPRA": 1.079723054983675, "MEPOLIZUMAB": 7.183560183295332, "METHOTREXATE": 2.5140709592911725, "MMRVAXPRO": 7.379085670287184, "NAGLAZYME": 16.14292577081708, "OMALIZUMAB": 5.443222600442429, "OPSUMIT": 1.455185549680445, "PEGASYS": 1.766529026547983, "PEGINTRON": 1.0132797757664114, "PRIVIGEN": 1.5373472895977085, "RITUXIMAB": 2.606658696923169, "ROACTEMRA": 1.7512610303369738, "ROTATEQ": 3.7530443921108825, "SILDENAFIL": 2.7089588197975654, "SIMPONI": 8.891630658650651, "STELARA": 2.352844292046478, "SUBOXONE": 1.4359355413647643, "SYNAGIS": 16.310887810141697, "TAMIFLU": 1.0582816136762545, "TOZINAMERAN": 1.0630797072563314, "TRACLEER": 1.1056191377705291, "XELJANZ": 4.161845376917523, "XOLAIR": 3.040112373374012, "ZOSTAVAX": 1.187668009603487, "null": 1.0417701430485864}
\ No newline at end of file
+{"CICLOSPORIN": 4.876283695750079, "DACLATASVIR": 153.81904732081443, "DELAMANID": 84.48300349248355, "PEGASYS": 9.53626242358278, "PEGINTERFERON": 87.96849830878531, "RIBAVIRIN": 21.21490797082938, "null": 0.3595625576964162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2669.json
index 0f560c4a7e5..1af05c84c67 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2669.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2669.json
@@ -1 +1 @@
-{"null": 1.254856573976389}
\ No newline at end of file
+{"COMIRNATY": 2.574763237365931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/267.json
index b2d035ec5bb..314e55022cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/267.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/267.json
@@ -1 +1 @@
-{"ABATACEPT": 14.165756972667689, "ACLASTA": 94.10219370372036, "ADALIMUMAB": 9.996477696392612, "APTIVUS": 110.52070008424252, "ARAVA": 2.7256640428272503, "AUBAGIO": 6.434005170611481, "AVAMYS": 30.99561154379193, "CICLOSPORIN": 2.163019012385277, "HUMIRA": 4.053585271267126, "JAKAVI": 4.0961994334941085, "KEYTRUDA": 2.0485290694181604, "LEVOFLOXACIN": 2.2072020919878814, "NEXAVAR": 4.338331987285797, "PEGASYS": 3.366536908045192, "QARZIBA": 137.8004464089082, "YESCARTA": 29.440642694940514}
\ No newline at end of file
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2670.json
index f64f3be866a..a9b5df182bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2670.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2670.json
@@ -1 +1 @@
-{"COMIRNATY": 3.947872624508932, "SPIKEVAX": 2.511613102518337}
\ No newline at end of file
+{"AZILECT": 155.5359141649399, "COMBIVIR": 9.845456742801852, "COMIRNATY": 0.8937938699086989, "GARDASIL": 2.72362327558573, "HIZENTRA": 58.01852144054012, "PEGASYS": 1.662631314555025, "PEGINTRON": 4.511070856971684, "PRIVIGEN": 29.2352067001578, "SPIKEVAX": 1.2758854625543126, "TOZINAMERAN": 1.185665981413448, "VAXZEVRIA": 1.2178463504776935, "ZOSTAVAX": 7.048656283964666, "null": 0.3264023237296428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2671.json
index b4af344e599..a9f66163fb3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2671.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2671.json
@@ -1 +1 @@
-{"ADALIMUMAB": 15.368706045196216, "COSENTYX": 27.19132323118374}
\ No newline at end of file
+{"ABACAVIR": 0.0686556795127724, "ABATACEPT": 0.0350899317050843, "ABILIFY": 0.0534950767782814, "ADENURIC": 0.8303495604429931, "AFINITOR": 0.1262736223769088, "ALIMTA": 0.4261552236680625, "AMIKACIN": 0.4185779458633539, "AMINOSALICYLIC": 0.2470248720278792, "APIDRA": 0.0756357890095076, "APIXABAN": 0.1526527178471803, "APROVEL": 0.8990920080745615, "ARANESP": 0.3184371515761056, "ARAVA": 0.0336294153207625, "ATAZANAVIR": 0.3655408932461882, "ATRIPLA": 54.29792737001157, "AVANDIA": 0.3408271038254345, "AVASTIN": 0.0970435357027137, "AVONEX": 2.842399202243638, "AZATHIOPRINE": 0.4109931346225993, "BENLYSTA": 0.109657671064335, "BEVACIZUMAB": 0.1744126502984347, "BIKTARVY": 1.1286377402767434, "BOSULIF": 0.242422991077671, "BRILIQUE": 0.2488878121786391, "BUDESONIDE": 0.0527789700770839, "BUMETANIDE": 0.8308152404738618, "BYDUREON": 0.2184408423901173, "BYETTA": 1.4580213852106958, "CABOMETYX": 0.1566268146840304, "CELECOXIB": 0.3019775601635325, "CELLCEPT": 0.5098523291690075, "CELSENTRI": 1.4226471241435803, "CICLOSPORIN": 0.6567278908285605, "CIMZIA": 0.0394428846470145, "CLOPIDOGREL": 0.3769820680736246, "COAPROVEL": 0.5208708948020633, "COMIRNATY": 0.0118696694907695, "COSENTYX": 0.0551913777215368, "CYMBALTA": 0.0729562851556115, "DAPAGLIFLOZIN": 1.8523650896734836, "DELAMANID": 0.4708870074159792, "DESCOVY": 1.0864611617231008, "DEXAMETHASONE": 0.083706024743027, "DOXORUBICIN": 0.1964261878654735, "DULAGLUTIDE": 1.6585105598499283, "DULOXETINE": 0.1237021044462492, "EFAVIRENZ": 0.4264583169991291, "ELIQUIS": 0.2718052738966708, "EMPAGLIFLOZIN": 0.5643349255349094, "EMTRICITABINE": 1.065667260124204, "ENBREL": 0.1068731650868417, "ENTECAVIR": 1.5121475855484665, "ENTRESTO": 0.7597790858860698, "EPIVIR": 0.3481753627492406, "ESOMEPRAZOLE": 0.661526806250878, "EXFORGE": 0.5422922661356553, "EXJADE": 0.3456219708575914, "FASLODEX": 0.1204558107855485, "FEBUXOSTAT": 1.7414557459511757, "FENTANYL": 0.0929241823756102, "FORXIGA": 0.4272197353337291, "GENVOYA": 1.53382145860695, "HEPSERA": 0.7684674382125493, "HIZENTRA": 0.1481715093912118, "HUMALOG": 0.6702802577150436, "HUMIRA": 0.1741590432231353, "HYDROCORTISONE": 0.3053343234671064, "IBRANCE": 0.1607945350180739, "IBUPROFEN": 0.145625856552836, "ICLUSIG": 0.2727173766566929, "INLYTA": 0.2212344245617156, "INSULIN": 0.4673590787709248, "INTELENCE": 1.1111772777782294, "INVIRASE": 1.6909761734046425, "INVOKANA": 0.8153026985532984, "IRBESARTAN": 0.3332136267893468, "IRON": 0.4927511092397232, "ISENTRESS": 0.5505478119134957, "JAKAVI": 0.145228598388185, "JANUMET": 0.826713731280409, "JANUVIA": 0.891609150326065, "JARDIANCE": 0.1416740017983229, "KALETRA": 3.676307014415471, "KARVEA": 1.5325228200574998, "KEPPRA": 0.0444470755586113, "KEYTRUDA": 0.111941926022846, "KYMRIAH": 0.1466667835313055, "KYPROLIS": 0.2998681114633837, "LANTUS": 0.4500951111619399, "LEVEMIR": 0.4900488464182583, "LEVOFLOXACIN": 0.1030223532482114, "LYRICA": 0.2173238682787514, "METFORMIN": 0.452239887312668, "METHOTREXATE": 0.1083426858403846, "MICARDIS": 1.153664576069711, "MIMPARA": 0.5637111924693213, "MIRCERA": 0.9109432353963628, "MULTAQ": 0.2693166090000264, "MYCOPHENOLATE": 0.4140659852964619, "NEXAVAR": 0.0537905820992695, "NORVIR": 0.6490611835148411, "NPLATE": 0.2586807287914004, "OLANZAPINE": 0.0415877209361063, "ONGLYZA": 0.5954427711795921, "OPSUMIT": 0.2759038326420788, "OZEMPIC": 2.5668716289223195, "PANTOPRAZOLE": 1.4312322466768164, "PEGASYS": 0.0214306866125845, "PEMBROLIZUMAB": 0.1976359317529943, "PEMETREXED": 0.5132446566536258, "PLAVIX": 0.2050238073562507, "RAPAMUNE": 0.29437352170182, "RASILEZ": 0.7324859768435054, "REVATIO": 0.626314422900663, "REYATAZ": 0.698420118996778, "ROACTEMRA": 0.0794968145388563, "RUXOLITINIB": 0.4155015185820073, "SHINGRIX": 0.0530457721460095, "SIMPONI": 0.0516073789457295, "SOLIRIS": 0.7169738643210746, "SPIKEVAX": 0.0183356205328502, "SPIRONOLACTONE": 1.154885597305149, "STELARA": 0.0788493987057671, "STRIBILD": 29.96502828292687, "SUTENT": 0.362509709224382, "TACROLIMUS": 0.6090750512941947, "TASIGNA": 0.3985401657029124, "TENOFOVIR": 14.40086325493597, "THIOTEPA": 1.0505676952048422, "TIVICAY": 1.787421824796075, "TOZINAMERAN": 0.0179854949346862, "TRACLEER": 0.1251856231891518, "TRIUMEQ": 0.7245562766718633, "TRULICITY": 0.448216276382723, "TRUVADA": 45.10198190313478, "UNSPECIFIED": 1.5351275944586371, "VALSARTAN": 0.5732354274609369, "VAXZEVRIA": 0.0060345732914884, "VELTASSA": 0.7785582540470115, "VIAGRA": 0.0906432897028182, "VICTOZA": 0.6233414006946494, "VIREAD": 21.520083417146942, "VOTRIENT": 0.1208604499548651, "XELJANZ": 0.2478504025356412, "XTANDI": 0.0674563385252545, "ZOMETA": 1.476389344806055, "ZOSTAVAX": 0.9848007328013764, "ZYPREXA": 0.1860302057443894, "null": 0.1927938053766626}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2672.json
index 31d0986ee8c..4aed8b338c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2672.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2672.json
@@ -1 +1 @@
-{"ASPARAGINASE": 70.36201745381456, "COMBIVIR": 41.75491384864407, "null": 2.710195527047615}
\ No newline at end of file
+{"ATRIPLA": 48.94047084490235, "STRIBILD": 14.579060174187846, "TRUVADA": 30.366109952556187, "null": 0.135061064445446}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2673.json
index 8cd2096c0d0..d844e618271 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2673.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2673.json
@@ -1 +1 @@
-{"COSENTYX": 66.08935205959591, "null": 1.144174766869385}
\ No newline at end of file
+{"ELIQUIS": 10.635460547687885, "ONGLYZA": 1410.3886988342722, "SPIKEVAX": 1.8769323326247345, "ZOSTAVAX": 42.45563083221289, "null": 0.2180543449361791}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2674.json
index f33e87221fe..c1c2d590e66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2674.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2674.json
@@ -1 +1 @@
-{"null": 1.4336687996498925}
\ No newline at end of file
+{"null": 0.4451908553052324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2675.json
index b6fc4ab3dad..e57eba0dc9b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2675.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2675.json
@@ -1 +1 @@
-{"ABATACEPT": 5.723888975939825, "ARAVA": 5.567050791520222, "ATEZOLIZUMAB": 4.1131135400732886, "BENLYSTA": 1.105061163440981, "CHLORHEXIDINE": 3.567740328264242, "CIMZIA": 3.5548786332912696, "COMIRNATY": 1.6685770689904538, "COVID19": 3.2423851859932724, "GARDASIL": 1.6878528919747051, "MMRVAXPRO": 1.3508914123094806, "NAGLAZYME": 6.819212420057196, "NIMENRIX": 1.296481727937022, "OMALIZUMAB": 1.9200461394033697, "RELVAR": 1.4846560198603047, "SHINGRIX": 1.74503417459918, "SPIKEVAX": 1.4788165725286526, "TOZINAMERAN": 3.272634632194375, "VAXZEVRIA": 1.47012292497658, "ZOSTAVAX": 2.3051840614357166}
\ No newline at end of file
+{"ALEMTUZUMAB": 7.294302226479661, "ARZERRA": 162.08569076814533, "COMIRNATY": 0.2321870500368672, "CYTARABINE": 3.988002242689352, "DEXAMETHASONE": 1.986229902916864, "ELIQUIS": 0.7682847960708383, "EXJADE": 5.563484214017677, "HUMALOG": 1.0364205813247584, "IBRUTINIB": 316.3992028786959, "IMBRUVICA": 134.70491792913182, "JAKAVI": 4.370996217257311, "NPLATE": 65.13886067572942, "OBINUTUZUMAB": 32.85476772337904, "OFATUMUMAB": 170.13014330783722, "RITUXIMAB": 22.175278819675206, "SIMPONI": 2.017092360891646, "SPIKEVAX": 0.1605387964924396, "STELARA": 1.9564263400136963, "TOZINAMERAN": 0.5013579902735126, "VAXZEVRIA": 0.0808874017248603, "VENCLYXTO": 193.5642667318214, "VENETOCLAX": 180.23586061947384, "ZOSTAVAX": 1.6150322724866424, "null": 0.6197680433478876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2676.json
index 92542eeeec3..117aece216e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2676.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2676.json
@@ -1 +1 @@
-{"AVAMYS": 14.316476362783142, "BUDESONIDE": 56.23921834332768, "COSENTYX": 3.0734887906043507, "NUCALA": 77.35007943592682, "RITUXIMAB": 9.56806695868124, "XOLAIR": 1.3228879342210489, "null": 1.731234989783364}
\ No newline at end of file
+{"DEXAMETHASONE": 11.545341091342928, "DOXORUBICIN": 49.77560763297469, "GAZYVARO": 153.9177200122778, "IBRUTINIB": 753.4167143014894, "IMBRUVICA": 199.282431268059, "RITUXIMAB": 33.96611630345069, "VENCLYXTO": 195.74492636581317, "VENETOCLAX": 121.38606270607632, "null": 0.2750427247057421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2677.json
index c0dcff10366..a3eafced072 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2677.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2677.json
@@ -1 +1 @@
-{"MMRVAXPRO": 2.030182087393097, "OMALIZUMAB": 5.614680047079582, "SHINGRIX": 1.869733161243308, "TOZINAMERAN": 2.437675179067164, "XOLAIR": 2.5926258146026218, "null": 1.3547442692890994}
\ No newline at end of file
+{"NPLATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2678.json
index 7ed25a9edf2..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2678.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2678.json
@@ -1 +1 @@
-{"NAGLAZYME": 224.98271827603617, "null": 1.2986623972505305}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2679.json
index 8295dedf282..eb9fe471302 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2679.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2679.json
@@ -1 +1 @@
-{"null": 20.003002129228943}
\ No newline at end of file
+{"VENCLYXTO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/268.json
index a5a1174a7e5..8c7abf2dd28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/268.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/268.json
@@ -1 +1 @@
-{"ABRAXANE": 1.2675298436494609, "ACTOS": 3.390804437383316, "ADEFOVIR": 12.476180096397185, "AFINITOR": 1.12858095801912, "AGENERASE": 8.297007844238493, "ALIMTA": 2.091530432423037, "ALL": 2.0029074851168747, "ALOXI": 5.256692338989005, "AMIKACIN": 2.8693614475672438, "AMINOSALICYLIC": 1.569746935722354, "APREMILAST": 2.3560331402429986, "APROVEL": 1.0639737181355204, "APTIVUS": 3.219699621697369, "ARIXTRA": 1.5023138359771553, "ASPARAGINASE": 2.427576404015586, "ATAZANAVIR": 2.505190556668073, "AUBAGIO": 3.931382417908347, "AVANDIA": 2.0078399660957147, "AVELUMAB": 3.945711070899304, "AXITINIB": 5.38940663197809, "AZATHIOPRINE": 2.0721269821970485, "AZILECT": 1.5350484506624378, "BARACLUDE": 11.98057454619779, "BASILIXIMAB": 1.1040437705967951, "BAVENCIO": 2.9893862390982284, "BEDAQUILINE": 11.289581391857604, "BETAFERON": 4.315551531010428, "BEVACIZUMAB": 1.2221073829564095, "BIKTARVY": 1.0945422656582529, "BLINATUMOMAB": 2.857184249412659, "BOSULIF": 4.210566486741768, "BRAFTOVI": 1.0270603130464586, "CABOMETYX": 3.041383162960215, "CANCIDAS": 7.5257957914691165, "CAPECITABINE": 1.563173828546603, "CARBIDOPA": 1.2299062545868549, "CASPOFUNGIN": 1.6636431402312837, "CELECOXIB": 2.1685728101286235, "CELLCEPT": 1.2944275698713552, "CELSENTRI": 5.06821736970525, "CICLOSPORIN": 1.8066300185645103, "CLOFARABINE": 1.7721710070294143, "COBIMETINIB": 3.054318742262958, "COMBIVIR": 4.1011758723239495, "COMTAN": 1.710248294170728, "COTELLIC": 1.665689365952807, "CRIXIVAN": 4.02779829037874, "CRIZOTINIB": 3.899768124345506, "CUBICIN": 2.137439192012651, "CYMBALTA": 1.7500086405377373, "CYTARABINE": 2.4100306900599446, "DACLATASVIR": 2.321318364335335, "DELAMANID": 3.405563244573649, "DENOSUMAB": 3.469085456758264, "DOCETAXEL": 1.076903892108164, "EFAVIRENZ": 5.43543523959479, "EMEND": 2.2303891107413003, "EMTRICITABINE": 3.582000136693249, "ENBREL": 3.316099199981201, "ENFUVIRTIDE": 4.843629254406811, "ENOXAPARIN": 1.0020486995287212, "ENTECAVIR": 9.492754356043614, "EPCLUSA": 1.0943371537123463, "EPIDYOLEX": 5.166685887179913, "EPIVIR": 4.515731423604952, "ERBITUX": 2.584117202608483, "ESMYA": 9.562365114975655, "EUCREAS": 2.839805805747653, "EXFORGE": 1.150596970366669, "EXJADE": 6.005797331883106, "EXVIERA": 5.204419829443654, "FASLODEX": 1.01796636483602, "FEBUXOSTAT": 1.555612667813394, "FULVESTRANT": 1.933160888597098, "FUZEON": 11.460503571753144, "GALVUS": 4.270871736889416, "GANCICLOVIR": 1.8696201687517309, "GEFITINIB": 2.94912070123708, "GILENYA": 3.046611549873918, "GLIVEC": 3.155830942503086, "HALAVEN": 1.826511507281332, "HARVONI": 1.232145406420317, "HEPSERA": 6.913328566193478, "HYCAMTIN": 1.8496186202425977, "IBUPROFEN": 1.0809869642193952, "ICLUSIG": 1.1968266914266086, "IMATINIB": 1.3434035540878506, "INSULATARD": 1.819118034073198, "INTRONA": 1.4245670161220003, "INVIRASE": 3.948482937859788, "IPILIMUMAB": 1.6356672366565082, "IRESSA": 2.495375072118109, "ISENTRESS": 6.043357164094914, "IVACAFTOR": 15.199951144193657, "JAKAVI": 1.4876325051130594, "KAFTRIO": 7.557386971503261, "KALETRA": 2.0762488656180764, "KALYDECO": 3.2811975552251385, "KESIMPTA": 1.27617908252441, "KETEK": 4.355758747178736, "KEYTRUDA": 1.2432096516413855, "KISQALI": 8.697353359952956, "LAMIVUDINE": 2.064056259812392, "LEFLUNOMIDE": 1.7765179310897672, "LEMTRADA": 1.6529452190831733, "LENVIMA": 1.752841376487864, "LEVOFLOXACIN": 2.170821670450734, "LOPINAVIR": 1.724045698648212, "LUMYKRAS": 4.91060464575573, "MANNITOL": 3.978084233443691, "MAVENCLAD": 5.8258627480972045, "MEKINIST": 1.5156498609082476, "MERCAPTOPURINE": 3.270414669057343, "METFORMIN": 1.6992166676442826, "METHOTREXATE": 1.4333324789448576, "MICARDIS": 1.406565413791022, "MULTAQ": 7.750640114159855, "MYCAMINE": 3.32319548744242, "NEVIRAPINE": 6.866572548616, "NEXAVAR": 4.30035839253584, "NILOTINIB": 1.4888446827018742, "NORVIR": 1.90334345272572, "NOXAFIL": 1.64393183760429, "NUBEQA": 6.88818400140666, "OCALIVA": 3.1516736017069285, "OFEV": 1.254025508441542, "OLANZAPINE": 2.1849079482094584, "OLAPARIB": 2.6815610492767963, "OLYSIO": 2.2722500177165923, "ONCASPAR": 1.5876361659541036, "OPDIVO": 2.1454070062029933, "OPSUMIT": 1.1018984767322983, "ORKAMBI": 4.888808557175275, "OZEMPIC": 1.4788687965366876, "PACLITAXEL": 1.660049082718479, "PALIPERIDONE": 3.1201835625851184, "PANTOPRAZOLE": 1.890480192990708, "PAZOPANIB": 6.005476762618425, "PEGASYS": 2.4862034969428417, "PEGINTERFERON": 2.1932950732357, "PEGINTRON": 1.1147370848152998, "PEMBROLIZUMAB": 1.184628565412161, "PEMETREXED": 1.0114415950390103, "PIOGLITAZONE": 2.081425096886747, "PLAVIX": 1.000659098929813, "PLEGRIDY": 1.9859688253786627, "PRETOMANID": 19.842860680126417, "PROPRANOLOL": 1.171438290878991, "PROTELOS": 3.333100499717094, "QARZIBA": 2.9143306912352585, "RASILEZ": 1.683652486741709, "REBETOL": 1.2320238518990037, "REBIF": 2.547049040670156, "REMDESIVIR": 25.074898089188316, "REYATAZ": 2.3407995353814126, "RIBAVIRIN": 1.7085644848985408, "RIBOCICLIB": 8.865599627801314, "RINVOQ": 2.3136299291816167, "RISPERIDONE": 2.106335512013991, "ROACTEMRA": 2.8387161044951994, "RUBRACA": 5.712813801765201, "RUXOLITINIB": 1.8605104881482124, "SAMSCA": 3.272590419130843, "SEMAGLUTIDE": 3.23207518169336, "SIMEPREVIR": 2.885063112311953, "SIRTURO": 4.805884049268032, "SOMATROPIN": 1.3285467949124534, "SOTORASIB": 10.805313105473848, "SOVALDI": 1.5978502247028217, "STIVARGA": 5.307689503512639, "STOCRIN": 3.564923615819831, "TACROLIMUS": 1.5059367486595685, "TAGRISSO": 1.1138290133939983, "TAMIFLU": 1.058405114386693, "TASIGNA": 3.008248203361484, "TAXOTERE": 1.3967314099300077, "TEMODAL": 1.9339934799760563, "TEMOZOLOMIDE": 1.3930457228793487, "TENOFOVIR": 4.80622794631563, "TERIFLUNOMIDE": 2.27424550433732, "TESTOSTERONE": 1.006908770291712, "TIVICAY": 1.5688961368156376, "TOCILIZUMAB": 2.014991254861531, "TOPOTECAN": 1.5627878068567755, "TORISEL": 1.018442862931472, "TRABECTEDIN": 7.781080583349353, "TRACLEER": 16.617943678441424, "TREMFYA": 1.3862150157026536, "TRISENOX": 4.456980771431938, "TRIUMEQ": 2.221817715406452, "TWINRIX": 1.7077718076761976, "UPADACITINIB": 2.0501458018937315, "VALDOXAN": 4.613056624396, "VEKLURY": 10.411061807185282, "VEMLIDY": 10.911000156161284, "VENCLYXTO": 1.1464058011317584, "VFEND": 5.240374653879671, "VIRAMUNE": 4.914150141272623, "VIREAD": 2.1396171183624624, "VORICONAZOLE": 3.2081831815878634, "VOTRIENT": 4.2779773441792575, "XALKORI": 5.693584396010497, "YONDELIS": 6.042228462807276, "ZELBORAF": 1.5032672288108873, "ZEPATIER": 2.894299571840142, "ZIAGEN": 5.377769299481594, "ZINBRYTA": 5.861718054897056, "ZOMETA": 1.424627429356071, "ZYPREXA": 4.010272484062591, "null": 1.60683132517056}
\ No newline at end of file
+{"ALEMTUZUMAB": 178.70105505534744, "ASPARAGINASE": 9.183100393507374, "BASILIXIMAB": 40.59654277619472, "BUDESONIDE": 14.144251510988653, "BUSILVEX": 48.6658719199235, "BUSULFAN": 95.49759484446402, "CELLCEPT": 9.580502273087346, "CICLOSPORIN": 41.644712476848206, "CIDOFOVIR": 178.91709454538486, "CYTARABINE": 11.417995204227672, "DEXAMETHASONE": 4.152352555391031, "FILGRASTIM": 14.02168012438511, "MELPHALAN": 71.32142619791969, "METHOTREXATE": 2.792046421402069, "MYCOPHENOLATE": 19.08039826910249, "RITUXIMAB": 4.653424953707644, "SOLIRIS": 3.1526652185126327, "SPINRAZA": 11.536564054113493, "SYNAGIS": 22.940543342728503, "THIOTEPA": 53.87190121599772, "null": 0.1963421097063602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2680.json
index 462ade3bc91..59432314651 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2680.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2680.json
@@ -1 +1 @@
-{"BYETTA": 28.94310438815108, "COSENTYX": 9.073528726766863, "JAKAVI": 29.29694100482786, "SAXENDA": 15.180222425405, "SUTENT": 1.9856600456531768}
\ No newline at end of file
+{"BOSULIF": 44.31738130229738, "BOSUTINIB": 185.56609482816117, "BUSULFAN": 4.06379189734301, "CELLCEPT": 1.8495879815552048, "CICLOSPORIN": 3.707172377544463, "COMIRNATY": 0.0452367299949319, "CYTARABINE": 3.415735213168298, "DASATINIB": 182.35477533878944, "DEXAMETHASONE": 1.4194484018259494, "DOCETAXEL": 2.7157715451279856, "DOXORUBICIN": 5.427430558132807, "GLIVEC": 71.92088625322938, "ICLUSIG": 233.67049887803984, "IMATINIB": 96.63830014303232, "IRINOTECAN": 8.464351500942604, "JAKAVI": 7.044115777540347, "NILOTINIB": 158.3877757950397, "NPLATE": 7.391607919050483, "PLAVIX": 1.1140528481841572, "RITUXIMAB": 2.8325395193778893, "SPRYCEL": 31.66536682013635, "STELARA": 1.9147975139308453, "TASIGNA": 172.43835615866848, "XELJANZ": 1.315988830129739, "null": 0.3380608783133336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2681.json
index 25cf623392d..3f465f36f3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2681.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2681.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 32.31847267070204, "CICLOSPORIN": 9.006529106562589, "ENTYVIO": 9.53971939204578, "KEYTRUDA": 56.974580259183725, "NEXAVAR": 12.243618517336646, "PEMBROLIZUMAB": 23.19455912006784, "STIVARGA": 9.22460950437574, "TEMODAL": 65.32830794778262, "TEMOZOLOMIDE": 187.3886423931176}
\ No newline at end of file
+{"BOSUTINIB": 259.00653254342683, "DASATINIB": 598.3027199529947, "ICLUSIG": 367.26038042018, "IMATINIB": 141.01430962269995, "NILOTINIB": 426.109057707447, "SPRYCEL": 67.67375155388085, "TASIGNA": 87.3314048498061}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2682.json
index e792a64c8c0..527adbaef9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2682.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2682.json
@@ -1 +1 @@
-{"ABILIFY": 3.2096263907320277, "ACETYLSALICYLIC": 72.70826667000149, "AFINITOR": 3.711984735048484, "ALISKIREN": 92.83224784284614, "ARIPIPRAZOLE": 1.473924862930118, "ATRIPLA": 1.019537413589248, "BENLYSTA": 1.1124527748959188, "BLINCYTO": 15.19177570764113, "BOSULIF": 2.7939572289236008, "BRAFTOVI": 1.6860604108174428, "BUMETANIDE": 11.562453375194776, "BUPRENORPHINE": 1.3292636977008745, "CAPECITABINE": 1.2229429627087265, "CARIPRAZINE": 28.250140462176905, "CHAMPIX": 1.5586263907829012, "COMTAN": 4.329843932287485, "DELAMANID": 6.702979451741325, "DEXAMETHASONE": 1.108141571715588, "ENTACAPONE": 7.421471110924092, "ESBRIET": 1.884934605406893, "FASLODEX": 1.1060046168145636, "FENTANYL": 1.365393736084426, "FORSTEO": 1.6913135933402046, "FULVESTRANT": 1.7989990433407652, "HUMALOG": 1.3061629934510752, "IBRANCE": 4.065972522334304, "INLYTA": 3.904834383043246, "JAKAVI": 1.326542199537022, "KAFTRIO": 1.7708079319171517, "KEPPRA": 1.1549264819558305, "KEYTRUDA": 1.5163237998498948, "KISQALI": 2.374733127119992, "LATUDA": 1.5695041241861836, "LEVODOPA": 5.543899076624224, "LUTATHERA": 6.5331749117395095, "LUTETIUM": 24.130595487623506, "LYRICA": 1.843397756338769, "MEKINIST": 1.2043789650324537, "MENVEO": 6.579215815227368, "MICARDIS": 1.7019955202769257, "NEXAVAR": 2.285514767836658, "NUCALA": 1.0225753810575102, "OLANZAPINE": 1.311725411960124, "OPSUMIT": 1.0035833864870984, "PEGASYS": 1.000190456638056, "PEGINTRON": 1.8537703384921256, "RELVAR": 3.762094569898144, "ROTATEQ": 1.739382474340644, "SAXENDA": 1.0898046205479714, "SIFROL": 6.481126856873063, "SOMATROPIN": 4.873289348430135, "SPRYCEL": 1.1071714839615303, "STALEVO": 3.147996652888444, "STIVARGA": 2.40509063864275, "SUTENT": 8.329306325406447, "TOZINAMERAN": 1.1423648757627465, "TRULICITY": 2.22811241881299, "VOTRIENT": 2.503788838840824, "XALKORI": 2.673495988593454, "XELJANZ": 1.238277063872497, "XTANDI": 2.564511658533738, "ZYPREXA": 1.327894259854649, "null": 1.2440654814490224}
\ No newline at end of file
+{"ICLUSIG": 388.9019820992351, "NILOTINIB": 427.7568557672759, "SPRYCEL": 63.31810231488716, "TASIGNA": 260.01300179730964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2683.json
index 37011cdfbcb..c717127c12b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2683.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2683.json
@@ -1 +1 @@
-{"null": 5.813785581687294}
\ No newline at end of file
+{"NPLATE": 94.18328327149382, "null": 1.04497558612586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2684.json
index 3c9d34a29fc..f46bf7afbd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2684.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2684.json
@@ -1 +1 @@
-{"BRILIQUE": 29.848110851684037, "BRINTELLIX": 4.904730417048333, "CLOPIDOGREL": 14.287845017436704, "DEXAMETHASONE": 1.5123147225160458, "DULOXETINE": 1.232870788712518, "EFIENT": 6.930246385623509, "ELIQUIS": 2.61792284215252, "ENOXAPARIN": 17.79309940954364, "EXJADE": 1.9515957078632693, "IBUPROFEN": 1.0867793730775352, "LEVOFLOXACIN": 1.8069644393492044, "LIXIANA": 3.197845709891234, "MMRVAXPRO": 2.269324918225508, "NPLATE": 10.495947772092176, "OMALIZUMAB": 1.5454556221796618, "PANTOPRAZOLE": 3.4578867794288284, "PLAVIX": 8.819045324516733, "ROACTEMRA": 1.6719379967379044, "SUTENT": 1.047857576202636, "TICAGRELOR": 19.24954589386545, "VAXZEVRIA": 1.7480935624123743, "XARELTO": 4.354286915935052, "null": 1.4375249696679373}
\ No newline at end of file
+{"ABILIFY": 0.3031443282243513, "ACLIDINIUM": 29.154484678147117, "ADCIRCA": 1.285848411927477, "AERIUS": 1.2080567046301487, "AFINITOR": 0.2207312898852961, "ALIMTA": 0.6185660725166392, "AMINOSALICYLIC": 0.3416907017571157, "ANORO": 16.103298671033716, "APIDRA": 0.235193764882424, "APIXABAN": 1.018126083853638, "ARANESP": 11.384741166799111, "ARAVA": 0.1015764512462922, "AUBAGIO": 0.5783715927224746, "AVAMYS": 10.07326633010168, "AVANDAMET": 2.151260034691944, "AVANDIA": 2.211175090819899, "BEDAQUILINE": 3.1307061051173064, "BENLYSTA": 0.2751802875007909, "BEVESPI": 34.20696330066647, "BLINDED": 10.863595264000493, "BOSULIF": 0.7538541659167374, "BRETARIS": 141.20322855998197, "BUDESONIDE": 3.0152899880774853, "BUPRENORPHINE": 0.5775631413143406, "BYDUREON": 0.910791999405167, "BYETTA": 1.5805453521992572, "CANAGLIFLOZIN": 6.2223785669884215, "CANCIDAS": 1.0089584102464328, "CELLCEPT": 0.1643328975071663, "CHAMPIX": 0.7565122033628824, "CIALIS": 1.5970344065105415, "CICLOSPORIN": 0.0956939275213713, "CIMZIA": 0.4104369941700571, "CLOPIDOGREL": 1.041146834748554, "COMIRNATY": 0.1044253423931906, "COSENTYX": 0.4457673228482313, "CYMBALTA": 0.2775097520908016, "DALIRESP": 48.60039458391499, "DAXAS": 12.746683007749708, "DELAMANID": 3.729251718997103, "DEXAMETHASONE": 0.4274468954198742, "DOXORUBICIN": 0.8106966769559719, "DUORESP": 11.203397740782124, "EFAVIRENZ": 0.9993434789176048, "ELIQUIS": 1.8120968111833573, "ENBREL": 0.1966298184535449, "ENTRESTO": 1.705556070865638, "ENTYVIO": 0.4590577324386686, "EPADERM": 45.24116119535811, "ESBRIET": 2.0352443159235345, "EVENITY": 1.2241046648130305, "EVISTA": 1.6452229386068893, "EXFORGE": 0.9619900376410364, "EXJADE": 0.7979299512199797, "FASENRA": 2.5589706294066588, "FENTANYL": 0.1977000440002548, "FIRDAPSE": 1.3135861984503563, "FLUTICASONE": 17.07673704005015, "FORSTEO": 1.7227011139499568, "GLYCOPYRRONIUM": 27.272757732136984, "HARVONI": 0.7064082184680152, "HIZENTRA": 2.685479986614635, "HUMALOG": 2.071413852776756, "HUMIRA": 0.7146434553902525, "HYDROCORTISONE": 0.421436818998549, "IBRANCE": 0.7286501174015871, "IBUPROFEN": 0.423857044837708, "INCIVO": 0.6212004909349503, "INCRUSE": 44.25154855779144, "INSULIN": 0.8234128302104541, "INVOKANA": 1.6346485525843415, "IRBESARTAN": 1.036329131266486, "IRON": 4.816072492132301, "ISENTRESS": 0.7598552999682214, "JANUMET": 1.8780820620978884, "JANUVIA": 3.046042114918674, "JARDIANCE": 0.5790992675922968, "KEPPRA": 0.2093730756754364, "KEYTRUDA": 0.5216639673680464, "LANTUS": 1.6118066535307831, "LEVEMIR": 1.3861036207290314, "LEVETIRACETAM": 0.2610499579200101, "LEVOFLOXACIN": 0.5212514339644023, "LYRICA": 2.2556359817082177, "MEPOLIZUMAB": 5.356797525122354, "METHOTREXATE": 0.2938437723374061, "MULTAQ": 1.5199605127729694, "NOT": 1.0006285599717957, "NPLATE": 2.272520148987166, "NUCALA": 2.746855945362133, "OFEV": 0.630088014063738, "OLANZAPINE": 0.3934295016350879, "OMALIZUMAB": 3.066504321630501, "ONBREZ": 27.054889076649783, "ONGLYZA": 2.5208491743472883, "OPSUMIT": 3.213434841493332, "PANTOPRAZOLE": 3.081143909935779, "PEGASYS": 0.4983908389488387, "PEGINTERFERON": 0.3295422094519041, "PEGINTRON": 0.8254098464306793, "PLAVIX": 0.8694964422210575, "PREGABALIN": 1.0346516932665173, "RELVAR": 6.210501689746335, "REVATIO": 8.303919162191285, "REYATAZ": 1.5478229639784982, "RINVOQ": 0.3704687570900872, "RIVAROXABAN": 3.486451176929566, "ROACTEMRA": 0.3810261200290637, "SEEBRI": 11.00004518009037, "SHINGRIX": 0.1649603385487229, "SILDENAFIL": 1.3430500690560754, "SIMPONI": 0.5171312981203753, "SOLIRIS": 0.2913933987431658, "SPIKEVAX": 0.1256862740133898, "SPIRONOLACTONE": 1.2653660860248666, "SPRYCEL": 1.31014857647441, "STELARA": 0.6280508041464806, "SUBOXONE": 0.9642903037315256, "SUTENT": 0.3319778450819752, "TAMIFLU": 0.4535983556598846, "TASIGNA": 1.202695895264065, "TOVIAZ": 0.5689935974403699, "TOZINAMERAN": 0.1665278907957039, "TRACLEER": 3.4988913242046955, "TRELEGY": 43.04840004576747, "TREMFYA": 1.2697811023672527, "TRULICITY": 0.5594422786749672, "TRUVADA": 0.0669680435627979, "ULTIBRO": 34.97678144663863, "UMECLIDINIUM": 49.18476769189711, "VALSARTAN": 1.6345591665039128, "VAXZEVRIA": 0.0693492747517925, "VELTASSA": 1.590571778472316, "VFEND": 1.2486693509512885, "VIAGRA": 1.1104255362989452, "VICTOZA": 0.3357702211653209, "VOTRIENT": 0.2258286003266939, "XARELTO": 2.593022001589105, "XELJANZ": 1.4597192085654047, "XOLAIR": 2.6170288884405863, "XTANDI": 1.1151604344787118, "ZOMETA": 4.592053406444897, "ZOSTAVAX": 5.565080657523868, "ZYPREXA": 0.6102685171995873, "null": 2.02471452351844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2685.json
index f4bef38833f..57471dd66de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2685.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2685.json
@@ -1 +1 @@
-{"SPIKEVAX": 18.47764831145529}
\ No newline at end of file
+{"COMIRNATY": 0.6622287977260315, "null": 0.4323058731990355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2686.json
index 50b17729368..3da59600997 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2686.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2686.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 35.34326416617147, "COMBIVIR": 14.1774643664846, "SPIKEVAX": 2.512676466444255, "TRACLEER": 8.83963864030103}
\ No newline at end of file
+{"VORICONAZOLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2687.json
index 5bd93f403d4..11814e129b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2687.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2687.json
@@ -1 +1 @@
-{"SPIKEVAX": 22.650086034836544}
\ No newline at end of file
+{"EFAVIRENZ": 170.11803473857734, "SYNAGIS": 186.17440420032395, "null": 0.5892452548821849}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2688.json
index 3cefaffc114..2e3b81edf90 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2688.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2688.json
@@ -1 +1 @@
-{"null": 4.91416801219962}
\ No newline at end of file
+{"BEDAQUILINE": 23.680890528521623, "ESBRIET": 16.037129809495376, "OCEAN": 1247.990565363114, "OFEV": 19.23280302137393, "OPSUMIT": 10.752047737525167, "REVATIO": 22.147652394083053, "SPINRAZA": 83.49504945234207, "SYNAGIS": 30.29644419137296, "TRACLEER": 28.86776117167693, "ZOSTAVAX": 6.33160570553631, "null": 0.6163741406204699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2689.json
index 7c0916cc444..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2689.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2689.json
@@ -1 +1 @@
-{"null": 1.4605737060642596}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/269.json
index df0b4a5dd3d..e8bec2b5dfb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/269.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/269.json
@@ -1 +1 @@
-{"SPIKEVAX": 35.163367348266625}
\ No newline at end of file
+{"ALEMTUZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2690.json
index b4cd04313fe..6c37a1520a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2690.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2690.json
@@ -1 +1 @@
-{"null": 3.944101558416704}
\ No newline at end of file
+{"ACLIDINIUM": 20.93627173504365, "ADALIMUMAB": 21.033229474782072, "ALIGN": 187.57056845762975, "AMINOSALICYLIC": 100.3854824212843, "APIXABAN": 2.534285766969956, "ARAVA": 0.1741610333089199, "ASPARAGINASE": 13.991273260565896, "AVAMYS": 52.33940725798912, "BUDESONIDE": 112.4732928564592, "COMBIVIR": 8.872108752399962, "COMIRNATY": 0.0701207909140003, "CYTARABINE": 3.443327558982505, "ENBREL": 0.5246259254331312, "ESOMEPRAZOLE": 5.114276306638289, "FLUTICASONE": 10.274363621390227, "GARDASIL": 0.5830941381191048, "MEPOLIZUMAB": 1.904543794280236, "METHOTREXATE": 6.217406039665358, "NUCALA": 8.765574231444646, "OMALIZUMAB": 2.4469243442264736, "PREGABALIN": 31.475393162468443, "SIMPONI": 0.5130423715174296, "SPIKEVAX": 0.0445669908370432, "VAXZEVRIA": 0.0481129267180466, "XELJANZ": 0.3250865550626591, "XOLAIR": 0.5938084841781981, "ZOSTAVAX": 1.659566722806891, "ZYPREXA": 0.4954513837128967, "null": 0.1805734461835684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2691.json
index afa8a40ce53..c447d2783a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2691.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2691.json
@@ -1 +1 @@
-{"ABILIFY": 1.7837671772732535, "ATRIPLA": 51.50605071771121, "BUPRENORPHINE": 1.3436453694996582, "KALETRA": 2.5094102097261235, "PLAVIX": 1.0407661138547046, "SIFROL": 2.3264920782076506, "STRIBILD": 47.41659546093008, "TRUVADA": 29.370968323767038, "VIREAD": 21.96826897371798}
\ No newline at end of file
+{"AVAMYS": 19.070180313338792, "BUDESONIDE": 4.566296981391711, "CICLOSPORIN": 14.583068980697966, "COMIRNATY": 0.5431152282723813, "IRON": 53.846276927701176, "OMALIZUMAB": 25.720686189487587, "SPIKEVAX": 1.6178367753325302, "TOZINAMERAN": 2.1441269114876107, "VAXZEVRIA": 0.1467365099097447, "XOLAIR": 90.44937830054408, "null": 0.2822201848753557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2692.json
index ea5b658571c..3f3ead18445 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2692.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2692.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 22.90318644797652}
\ No newline at end of file
+{"null": 0.8542544306861334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2693.json
index 5b412fde735..9bfc970c56a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2693.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2693.json
@@ -1 +1 @@
-{"CYMBALTA": 5.415282170347111, "ELLAONE": 92.73931409255113, "EVRA": 37.73428142583202, "FASENRA": 10.090777460545578, "FOLLITROPIN": 682.5412023326703, "GARDASIL": 2.4706034617320998, "GNRHANALOG": 32649.084267910934, "GONALF": 98.07945434737492, "KEPPRA": 2.0875163270944563, "PEGASYS": 1.3503773013635554, "PUREGON": 228.98950167502068, "SUBOXONE": 3.814897695120031, "null": 1.0479833926921065}
\ No newline at end of file
+{"null": 3.030987492471895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2694.json
index 1c472909aaf..ee192127fe6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2694.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2694.json
@@ -1 +1 @@
-{"null": 4.087854129026545}
\ No newline at end of file
+{"null": 1.2235218531283787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2695.json
index 277caa27a71..61219823aa0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2695.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2695.json
@@ -1 +1 @@
-{"null": 2.270709421972378}
\ No newline at end of file
+{"ASPARAGINASE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2696.json
index ee66035385f..9020260e638 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2696.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2696.json
@@ -1 +1 @@
-{"BUDESONIDE": 52.61492340295462}
\ No newline at end of file
+{"SPRYCEL": 246.3563302740834, "null": 0.5209290316249117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2697.json
index 4d17ebfdf82..497c0d45cd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2697.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2697.json
@@ -1 +1 @@
-{"null": 1.4303389403425195}
\ No newline at end of file
+{"null": 3.4802785401047998}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2698.json
index 4633cb253c0..731a739207a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2698.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2698.json
@@ -1 +1 @@
-{"AERIUS": 5.5363913969215535, "ALDARA": 2.182924149825864, "APROVEL": 3.734160504931813, "ASPARAGINASE": 1.2612768591252888, "AUBAGIO": 1.533557259255915, "AVAMYS": 16.34384639890735, "BEXSERO": 2.410617965282814, "BONVIVA": 1.6807106182949785, "BOSULIF": 1.0648088557645996, "BRILIQUE": 1.0556973826555158, "CHAMPIX": 1.1868381806396986, "COAPROVEL": 2.304956378315354, "COMIRNATY": 1.0395698469565289, "COMPRESSION": 56.141500484418025, "COSENTYX": 3.6496983025429497, "DULOXETINE": 1.1168725313050574, "DUPIXENT": 3.694088681694117, "ELIQUIS": 1.2558180453679495, "ENTYVIO": 1.371497746995512, "ERLEADA": 3.123227063737258, "EUCREAS": 3.4967921072958306, "EXFORGE": 1.1976759725486583, "FASENRA": 2.596636665497345, "FLEBOGAMMA": 1.93132124193378, "FLUTICASONE": 3.328455224832587, "GALVUS": 4.109838102645774, "GARDASIL": 1.400154335914165, "HIZENTRA": 1.5562853516370967, "HUMAN": 1.5633677826511772, "HYDROCORTISONE": 7.207423631085216, "ICLUSIG": 1.3225582418364434, "INCIVO": 3.3150302754689247, "INFANRIX": 2.3981527868361106, "IRBESARTAN": 3.2869846394520734, "IRESSA": 2.935566774734069, "JANUVIA": 1.1623244725695752, "KEPPRA": 1.015069697788899, "KEYTRUDA": 1.159553441610836, "LEVETIRACETAM": 1.058300386526883, "MEPOLIZUMAB": 6.206163741687442, "METFORMIN": 4.663305494999279, "MICARDIS": 1.2681925592898415, "MMRVAXPRO": 3.418287827688867, "NOVONORM": 5.52689235654284, "NUCALA": 3.318838805740992, "OLYSIO": 2.2986677950224768, "OMALIZUMAB": 1.2930335567215965, "PANTOPRAZOLE": 1.2284728182305402, "PEGASYS": 1.9278619841948728, "PEGINTERFERON": 1.7078138021944285, "PEGINTRON": 1.2435174416241732, "PEMBROLIZUMAB": 1.2471131052600066, "PREVENAR": 2.9660772002206333, "PRIVIGEN": 4.765227278160462, "PROTELOS": 5.914249164916635, "PROTOPIC": 8.863869691351558, "REBETOL": 1.5403423696744805, "RELVAR": 1.822205718554426, "REMICADE": 1.5457151242343945, "RIBAVIRIN": 1.5075897030255183, "RINVOQ": 3.2567135673373167, "ROACTEMRA": 1.4507532691758658, "ROTATEQ": 1.2728978634550112, "SHINGRIX": 1.4609107556956027, "SKYRIZI": 4.736086608017973, "STELARA": 2.0403560357318518, "TAGRISSO": 1.1939640983164954, "TAMIFLU": 1.2828681906044308, "TOCOPHEROL": 15.21187802587053, "TREMFYA": 3.8311504971157206, "TWINRIX": 2.5250214162206124, "XOLAIR": 1.7772026315331657, "ZINBRYTA": 10.35389393301356, "ZOSTAVAX": 1.519406909649377, "null": 1.1849261086769511}
\ No newline at end of file
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2699.json
index 8987f8ed1cd..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2699.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2699.json
@@ -1 +1 @@
-{"PEGINTRON": 8.603176086683266}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/27.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/27.json
index b3a58b2614b..46248b5dc4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/27.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/27.json
@@ -1 +1 @@
-{"ARIXTRA": 70.51519536618059, "CLOPIDOGREL": 10.114151823966848, "ELIQUIS": 7.293286651830681, "ENOXAPARIN": 135.36406199380917, "INHIXA": 81.90071154690648, "PLAVIX": 6.28994304063291, "XARELTO": 19.39152434148882, "null": 4.09094865253149}
\ No newline at end of file
+{"ADALIMUMAB": 1.2121977252453306, "AFINITOR": 4.547060998182137, "BYETTA": 10.884716350995316, "CIMZIA": 1.1792911669283537, "FORSTEO": 4.254243176166805, "JANUMET": 4.2457376011247, "JANUVIA": 9.111805541926955, "KALETRA": 5.407843969586612, "LANTUS": 2.3554896944164314, "SUTENT": 0.9189663222682948, "XELJANZ": 2.8837374521929737, "ZOSTAVAX": 5.164427599561275, "ZYPREXA": 1.7087230235173954, "null": 1.6881369525788854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/270.json
index 47a17cd2322..4aedf6f3c5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/270.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/270.json
@@ -1 +1 @@
-{"null": 1.3959986505165196}
\ No newline at end of file
+{"SPIKEVAX": 21.47579472376663}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2700.json
index 3ea8a8109ed..44a549b74c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2700.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2700.json
@@ -1 +1 @@
-{"COMIRNATY": 1.182262241457243, "null": 1.5685937130292875}
\ No newline at end of file
+{"EYLEA": 159.08912861663364, "null": 1.4137143261316634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2701.json
index a615f947b1a..3e7eb247c07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2701.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2701.json
@@ -1 +1 @@
-{"CICLOSPORIN": 6.081173944801256, "PROTOPIC": 434.2928380819413, "RINVOQ": 258.34599891787883, "UPADACITINIB": 420.7021269661533}
\ No newline at end of file
+{"COMIRNATY": 0.4475934124428719, "GARDASIL": 6.40968737843045, "null": 1.5657116247113405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2702.json
index 3501290efa4..e989223f0d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2702.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2702.json
@@ -1 +1 @@
-{"COMIRNATY": 1.522985505241519, "TREMFYA": 29.83019089403181}
\ No newline at end of file
+{"ABILIFY": 0.5809370515761698, "AFINITOR": 0.2681018542951933, "APIXABAN": 0.3235206826999154, "APROVEL": 1.5880559536066388, "ARAVA": 0.0287182989111155, "AVANDIA": 0.2991845719316883, "BEVACIZUMAB": 0.7237590981848573, "BRIDION": 4.780937359662325, "BRILIQUE": 0.6332462353786947, "BUPIVACAINE": 1.2117827043307616, "CASPOFUNGIN": 2.049489649751181, "CELLCEPT": 0.5739065386272741, "CHAMPIX": 0.2950869744684501, "CICLOSPORIN": 0.4051402346228818, "CIMZIA": 0.097955490456979, "CLOPIDOGREL": 1.5176190316477889, "COAPROVEL": 1.2446612244368758, "COMIRNATY": 0.7766126231445607, "CYMBALTA": 0.3305560674166698, "CYTARABINE": 0.4165824643203819, "DEXAMETHASONE": 1.1034876709847237, "DOCETAXEL": 0.3977289735828901, "DULOXETINE": 0.9411150088689012, "ELIQUIS": 0.501460155737607, "ENTRESTO": 0.8970415768263268, "EXFORGE": 0.9581328489072024, "EXJADE": 0.8460136463418421, "FASLODEX": 0.4107718941775317, "FENTANYL": 3.9650490096963367, "FORSTEO": 0.5198477125078116, "GARDASIL": 1.2801961105401505, "GLIBENCLAMIDE": 2.166189922860537, "GLUCAGON": 5.373584282813225, "HUMALOG": 0.1522145889964934, "HYDROCORTISONE": 0.6943687875769404, "IBUPROFEN": 0.6168856465831861, "INCIVO": 1.2119713558329286, "IRINOTECAN": 0.8822029578754818, "JAKAVI": 0.6573655059684971, "JARDIANCE": 0.7533019514713133, "JEVTANA": 2.558965281842434, "KEPPRA": 0.3402322898044318, "KEYTRUDA": 0.2364302759104365, "LACOSAMIDE": 1.714861911365307, "LANTUS": 0.1246040440984156, "LEVEMIR": 0.4882707846987977, "LEVETIRACETAM": 0.6102074001999366, "LEVOFLOXACIN": 0.8792024211225012, "MEKINIST": 0.3827029415423291, "MELATONIN": 1.298339461376238, "METHOTREXATE": 0.2463932763390331, "MICARDIS": 1.61937405259319, "MIDAZOLAM": 4.287978147928579, "MMRVAXPRO": 0.6162310754874972, "NEULASTA": 0.7257982309711994, "NEXAVAR": 0.379032294021943, "NIMENRIX": 0.5835246208406522, "NOT": 1.069581324447508, "OLANZAPINE": 1.2551104787370346, "OPSUMIT": 0.630033207741361, "PANTOPRAZOLE": 0.5817610931910396, "PEGASYS": 0.1760332183712127, "PEGINTERFERON": 0.4235155401237691, "PEGINTRON": 0.1857046827720986, "PLAVIX": 0.7238048344869423, "PREGABALIN": 0.9374725371197188, "PRIVIGEN": 1.1565161331231129, "PROPRANOLOL": 6.743792667818018, "RASILEZ": 2.292286114997746, "RISPERIDONE": 2.420592657576212, "RIVAROXABAN": 3.017243762437892, "ROACTEMRA": 0.8633173281984361, "SAXENDA": 0.5826247459725326, "SHINGRIX": 1.1866635701497523, "SIFROL": 2.080122945048522, "SILDENAFIL": 2.360588013235098, "SIMPONI": 0.1664377170530083, "SPIKEVAX": 0.4793692121502643, "STIVARGA": 0.3288858597135318, "SUFENTANIL": 15.04516960572782, "SUTENT": 0.253450596502512, "TAMIFLU": 0.6089657879295926, "TOZINAMERAN": 0.476496030234667, "TRACLEER": 1.7487631441742872, "TWINRIX": 7.181063100685838, "VAXZEVRIA": 0.4981222997446449, "VFEND": 1.056587221594866, "VIAGRA": 1.8214130575561, "VOTRIENT": 0.3998939551178146, "XOLAIR": 0.4837096466129783, "ZOMETA": 3.399830281282492, "ZYPREXA": 1.562458054749009, "null": 2.7544846635835905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2703.json
index 6e93f4133a5..5f8732af153 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2703.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2703.json
@@ -1 +1 @@
-{"null": 1.1646108727749316}
\ No newline at end of file
+{"null": 5.8923329929681945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2704.json
index 04d488ee31f..d6ce36922fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2704.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2704.json
@@ -1 +1 @@
-{"null": 1.2064544046879329}
\ No newline at end of file
+{"JARDIANCE": 106.39167161189556, "null": 0.5347424042529709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2705.json
index 397a08bde9d..872a797e58e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2705.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2705.json
@@ -1 +1 @@
-{"KEPPRA": 5.576731603440408, "null": 7.835082602018325}
\ No newline at end of file
+{"COMIRNATY": 0.4193431986307036, "VAXZEVRIA": 0.2494812908101806, "XOLAIR": 7.747470057477846, "null": 2.3699669597631066}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2706.json
index 9c563786776..a5903b33f84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2706.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2706.json
@@ -1 +1 @@
-{"BORTEZOMIB": 76.38988928367591, "SUTENT": 1.2663846161016583}
\ No newline at end of file
+{"COMIRNATY": 2.7852425236339804, "SPIKEVAX": 1.0687785511711578, "null": 0.6019220349538782}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2707.json
index 7b9a914e041..d5fe7c3fd80 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2707.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2707.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"BYDUREON": 57.00122048211932, "null": 2.059188424572364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2708.json
index 73deae56682..e80b05ca9f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2708.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2708.json
@@ -1 +1 @@
-{"GARDASIL": 72.2150223153652}
\ No newline at end of file
+{"AIMOVIG": 1.2770700916407542, "APIDRA": 4.341116026099007, "BENLYSTA": 42.14962042536585, "BIKTARVY": 12.11422014400143, "BRINTELLIX": 3.909133550941223, "BUDESONIDE": 0.8293961493124301, "BYDUREON": 18.35986161078049, "BYETTA": 2.481284853379462, "COMIRNATY": 0.0173609085862288, "ELIQUIS": 5.048006290301831, "EPCLUSA": 12.398339783711886, "FASLODEX": 2.3052435183439166, "IBRANCE": 1.0132685464233822, "ISENTRESS": 5.288423693033505, "JANUMET": 10.140700869031637, "JANUVIA": 6.323790004703636, "KEYTRUDA": 0.7003398736585826, "LANTUS": 0.8213000225898724, "NEULASTA": 2.7403140812014506, "NUCALA": 2.596815813874458, "PEGINTRON": 0.7846269106930944, "RELVAR": 15.403796822418244, "SUTENT": 0.2877238147743389, "TOZINAMERAN": 0.4174812593282748, "VAXZEVRIA": 0.1689692667804306, "XELJANZ": 2.4532689919476094, "XTANDI": 0.9472608064970384, "ZOSTAVAX": 0.7135479589949031, "null": 2.555953573875968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2709.json
index 7ea56ed71ee..9bbfbc9d959 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2709.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2709.json
@@ -1 +1 @@
-{"BRINTELLIX": 42.90338365939984, "UROREC": 278.87763042882534, "VIAGRA": 26.15578811039196, "null": 3.060396797059034}
\ No newline at end of file
+{"null": 1.197373981604554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/271.json
index 19c062499ae..056e5b4282b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/271.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/271.json
@@ -1 +1 @@
-{"null": 2.387804269380746}
\ No newline at end of file
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2710.json
index 479ee3c859a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2710.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2710.json
@@ -1 +1 @@
-{"BRINTELLIX": 5.439707231671068, "CYMBALTA": 2.3462500181350947, "SILODOSIN": 429.8428525703207, "SILODYX": 137.4318489637387, "UROREC": 182.75982508068552, "VIAGRA": 179.48332459765524, "ZYPREXA": 1.6958791536928204, "null": 3.396604241994385}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2711.json
index 0cd61c541cf..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2711.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2711.json
@@ -1 +1 @@
-{"BRINTELLIX": 6.717960593777849, "SILODOSIN": 286.1101086178015, "SILODYX": 726.424772227731, "UROREC": 1366.275005441801, "VIAGRA": 44.64907448214492, "null": 3.941122329958113}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2712.json
index 495bf45a255..8679cb18d1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2712.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2712.json
@@ -1 +1 @@
-{"APIXABAN": 1042.0477678571517, "ELIQUIS": 3.968887028947694, "ENTRESTO": 6.896740868282619, "ESOMEPRAZOLE": 15.696630541394146}
\ No newline at end of file
+{"ENTRESTO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2713.json
index 3f22c31fd70..1c58ab213b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2713.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2713.json
@@ -1 +1 @@
-{"APIXABAN": 241.24298645012647, "ARIPIPRAZOLE": 7.309745540375416, "BUMETANIDE": 37.77797055980027, "DASATINIB": 63.224074895130514, "ELIQUIS": 6.503314460189596, "ENTRESTO": 35.7475720262455, "HERCEPTIN": 12.262746213510905, "MEKINIST": 7.852849835832617}
\ No newline at end of file
+{"null": 1.357340192540443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2714.json
index 7a649c16a4a..d22e9f89bdd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2714.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2714.json
@@ -1 +1 @@
-{"AFINITOR": 3.0706982150428592, "ALIMTA": 1.122412613457562, "APIXABAN": 2.4558304065227428, "ARIPIPRAZOLE": 1.8172696613189765, "ASPARAGINASE": 2.19611041313432, "AVANDIA": 2.3196035920313878, "AVASTIN": 4.054034430740322, "AZACITIDINE": 2.48437801264004, "BEVACIZUMAB": 2.343671456373107, "BINOCRIT": 14.655123957676537, "BONVIVA": 6.229906672438436, "BRAFTOVI": 4.425536664978186, "BRILIQUE": 3.424908506215968, "BUMETANIDE": 7.202621769364409, "BUSILVEX": 16.800757351779417, "CABOMETYX": 1.6167866659889492, "CAELYX": 5.790505029138122, "CAPECITABINE": 4.319186885059996, "CARFILZOMIB": 4.879307666173311, "CELLCEPT": 1.267827552850354, "CLOPIDOGREL": 2.8981634519498822, "COBIMETINIB": 10.289766375109766, "COTELLIC": 14.841143333941892, "CYTARABINE": 1.3897907960978753, "DABRAFENIB": 28.59351053125258, "DAPAGLIFLOZIN": 12.036689799676948, "DENOSUMAB": 5.64644267530151, "DEXAMETHASONE": 1.101476208030361, "DOCETAXEL": 19.65662482842396, "DOXORUBICIN": 5.2485025127004175, "EDOXABAN": 31.46523161495838, "ENTRESTO": 32.600404703756325, "EXJADE": 1.758176396635031, "FASLODEX": 1.7159730431071782, "FENTANYL": 1.8173584746756704, "HERCEPTIN": 86.36710166560017, "ICLUSIG": 4.9799410910838615, "INLYTA": 1.828010222619137, "IRBESARTAN": 3.929027789832991, "IRESSA": 1.704728976872328, "IRINOTECAN": 3.60207960532419, "IVABRADINE": 24.22491825993602, "KEYTRUDA": 1.087994757440686, "KYPROLIS": 16.78775303233424, "LENVIMA": 4.071966007755188, "MABTHERA": 3.183457138654644, "MEKINIST": 20.20283254462189, "MIDAZOLAM": 1.494314512107954, "MULTAQ": 8.172417815673962, "NEXAVAR": 1.9008754744598664, "OLANZAPINE": 1.0337152790991908, "PACLITAXEL": 12.104541462081706, "PANTOPRAZOLE": 3.985439746696489, "PERJETA": 18.93911789607467, "PERTUZUMAB": 75.59941775510055, "RITUXIMAB": 2.036429819355835, "SUTENT": 4.432018867359169, "TAGRISSO": 11.295137675058209, "TASIGNA": 1.2245203625643295, "TRAMETINIB": 25.74398628167961, "TRASTUZUMAB": 48.92501618829007, "VALSARTAN": 25.86129382237018, "VOTRIENT": 9.94933144988663, "VYXEOS": 28.066634161035328}
\ No newline at end of file
+{"ARIPIPRAZOLE": 522.8631147354664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2715.json
index f7c6b510aa0..c2f791f58f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2715.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2715.json
@@ -1 +1 @@
-{"SPIKEVAX": 33.36303800782902}
\ No newline at end of file
+{"CHAMPIX": 7.383475853073325, "COMIRNATY": 0.1544857942419558, "CYMBALTA": 5.069620139108316, "ZOSTAVAX": 7.872879070741567, "null": 1.2543129859762447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2716.json
index e67c00fe5d9..9183d8022cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2716.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2716.json
@@ -1 +1 @@
-{"null": 5.879276102958377}
\ No newline at end of file
+{"ATRIPLA": 16.94770191990752, "COMIRNATY": 0.0536374995510472, "ELIQUIS": 0.8355351310344248, "FORSTEO": 4.862508655464087, "HUMIRA": 5.081659476452127, "IBRANCE": 1.481663056241486, "KEPPRA": 2.517694702845303, "LAMIVUDINE": 12.020634184707609, "LANTUS": 1.8122244701494588, "MELATONIN": 13.654121089811504, "STELARA": 1.2297904470564511, "STRIBILD": 11.025723719402247, "TOZINAMERAN": 0.2284227594502431, "TRUVADA": 7.993901502456419, "VAXZEVRIA": 0.1613718857921506, "XELJANZ": 0.9789177384439266, "XTANDI": 1.838358032706908, "null": 0.627328287872604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2717.json
index 5d13767dfba..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2717.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2717.json
@@ -1 +1 @@
-{"ARAVA": 9.311176102348565, "AZATHIOPRINE": 102.90189639305636, "ENBREL": 55.28532005285244}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2718.json
index 495559a1937..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2718.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2718.json
@@ -1 +1 @@
-{"ARAVA": 6.080852419362097}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2719.json
index ed199bb76c6..c7c74a0c1cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2719.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2719.json
@@ -1 +1 @@
-{"COVID19": 1.5490402174383784, "CYMBALTA": 6.03241675512855, "TOZINAMERAN": 1.2766094352179211, "null": 1.6278216940099106}
\ No newline at end of file
+{"AFINITOR": 10.43567843204312, "ANAKINRA": 17.311112621269245, "AZATHIOPRINE": 85.32997791600587, "CABOMETYX": 21.10171661978338, "CICLOSPORIN": 11.235447184583856, "PAZOPANIB": 376.3078547219088, "SIMPONI": 4.922833260655205, "STELARA": 3.918734759548834, "SUTENT": 9.14076398062605, "VOTRIENT": 28.76355627670105, "null": 0.2312378635828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/272.json
index 66622754f8c..c7eba6a54bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/272.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/272.json
@@ -1 +1 @@
-{"NEXAVAR": 17.109712630113386}
\ No newline at end of file
+{"COMIRNATY": 0.4744867698885266, "null": 1.143184893386738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2720.json
index 27dbfb7c853..3297c35f84f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2720.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2720.json
@@ -1 +1 @@
-{"AUBAGIO": 2.569716159838083, "BRINTELLIX": 4.5883350338775735, "BUPIVACAINE": 3.763583928994104, "CAPECITABINE": 1.6179912954308808, "CHAMPIX": 1.4141818876298542, "CYMBALTA": 77.96852408160106, "DULOXETINE": 3.0863214167963595, "FAMPYRA": 2.327878863103464, "LYRICA": 1.1237506136251174, "SHINGRIX": 1.1990070238714192, "TOZINAMERAN": 1.408576034833415, "null": 1.2315095519496373}
\ No newline at end of file
+{"IBUPROFEN": 10.109739423056384, "KEPPRA": 7.464477834214778, "null": 5.699782070657371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2721.json
index 0c9c129ff0c..6d90a7f5c8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2721.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2721.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3401410211262152, "SPIKEVAX": 14.818124630254111}
\ No newline at end of file
+{"ABILIFY": 5.810207125388753, "DESCOVY": 61.899197137842, "EFAVIRENZ": 41.17202553950213, "IBUPROFEN": 10.489817364835014, "KEPPRA": 12.776725182032406, "null": 3.8760757521969738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2722.json
index cef5d62512f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2722.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2722.json
@@ -1 +1 @@
-{"FENTANYL": 20.19664212181884, "null": 2.6026397839377307}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2723.json
index 89d37f29ae4..8d6c181d140 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2723.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2723.json
@@ -1 +1 @@
-{"VIMPAT": 51.93661217876928, "null": 2.77772294951808}
\ No newline at end of file
+{"BUPRENORPHINE": 6.458290239127148, "COMBIVIR": 30.021965792978182, "CYMBALTA": 1.1872187394137084, "IBUPROFEN": 6.895170942029214, "KEPPRA": 8.48768246410119, "LEVETIRACETAM": 3.658521851593559, "SUBOXONE": 2.6078336283527324, "null": 5.670938868393591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2724.json
index 9c0cd263fa5..9263fa5f5ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2724.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2724.json
@@ -1 +1 @@
-{"COMIRNATY": 6.398561737497216}
\ No newline at end of file
+{"SYNAGIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2725.json
index d42047ea1bd..77fecf4c2d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2725.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2725.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 23.073940228132265}
\ No newline at end of file
+{"null": 9.662156967034903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2726.json
index 8baebee2bc7..6221529bc1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2726.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2726.json
@@ -1 +1 @@
-{"null": 2.1487608395327937}
\ No newline at end of file
+{"null": 1.2741546040657432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2727.json
index b51ae9748b1..629bbbef527 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2727.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2727.json
@@ -1 +1 @@
-{"IRBESARTAN": 97.0310900613415, "null": 2.2111223174168164}
\ No newline at end of file
+{"COMIRNATY": 2.869292159030437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2728.json
index e9bf10a50d6..dfe17a12cb2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2728.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2728.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 5.1379525926505805, "CELLCEPT": 1.6460832092936226, "FESOTERODINE": 339.64979337597475, "IBUPROFEN": 4.561890829333579, "LACOSAMIDE": 20.45671238813517, "MIDAZOLAM": 7.360294660049282, "OLANZAPINE": 5.405784864839431, "PROPRANOLOL": 26.210702152659383, "SPIRONOLACTONE": 22.613720660769097, "null": 7.245943164411023}
\ No newline at end of file
+{"METHOTREXATE": 16.88172827480902, "null": 5.3127683921745446}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2729.json
index 220e8e532ec..7094c403fed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2729.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2729.json
@@ -1 +1 @@
-{"null": 5.469820429167827}
\ No newline at end of file
+{"APTIVUS": 17988.291258625384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/273.json
index 2da9f39bd45..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/273.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/273.json
@@ -1 +1 @@
-{"ATRIPLA": 4.004929530804365, "TRUVADA": 2.169895356110505, "null": 1.035796029230767}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2730.json
index fca3d611a01..d089c4bd1cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2730.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2730.json
@@ -1 +1 @@
-{"null": 1.214829147932694}
\ No newline at end of file
+{"COMIRNATY": 0.2650087225946629, "DEXAMETHASONE": 3.636610799593918, "GARDASIL": 2.81011381527032, "KEPPRA": 2.6581361467549884, "LEVETIRACETAM": 20.53755957175016, "SPIKEVAX": 0.1571731375956892, "VAXZEVRIA": 0.1349707407434356, "ZYPREXA": 3.15310569170505, "null": 2.653168145352729}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2731.json
index 0447acf3202..ea79364ad89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2731.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2731.json
@@ -1 +1 @@
-{"null": 1.1640314761284227}
\ No newline at end of file
+{"ARIPIPRAZOLE": 5.288317745030533, "CICLOSPORIN": 1.6570333080158024, "COMIRNATY": 0.1730610395968734, "CYMBALTA": 2.4754834393416525, "DEXAMETHASONE": 1.661485490612906, "DULOXETINE": 24.135627420726333, "FENTANYL": 14.387142371917166, "GARDASIL": 3.666290331002765, "HYDROCORTISONE": 7.571594507158554, "IBUPROFEN": 8.130967822280532, "IRON": 17.820124537441547, "KEPPRA": 4.078226645786888, "LEVETIRACETAM": 2.4512112549588068, "MIDAZOLAM": 15.325846120334685, "MMRVAXPRO": 1.8641824605176749, "OLANZAPINE": 6.94908299830179, "SPIKEVAX": 0.1341623611108859, "TOZINAMERAN": 0.2201446278140472, "ZYPREXA": 2.074164085782093, "null": 2.268397313126686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2732.json
index 92401e5c1b2..193236494b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2732.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2732.json
@@ -1 +1 @@
-{"ABILIFY": 3.516840318054676, "ADENURIC": 1.38684025874773, "AERIUS": 2.332980052472557, "AGOMELATINE": 7.206060387942967, "ALOXI": 8.226379892404765, "AMIKACIN": 7.218605522408021, "AMINOSALICYLIC": 20.009553539409172, "ARIPIPRAZOLE": 11.210167447230132, "ARSENIC": 253.63140734918252, "ASENAPINE": 8.588262012059259, "ATAZANAVIR": 1.159889214179885, "BEDAQUILINE": 67.4492889910647, "BENZODIAZEPINE": 4.489106397781578, "BENZODIAZEPINES": 8.43297277301866, "BETMIGA": 1.0588982077311329, "BOSULIF": 1.3542539288615263, "BRAFTOVI": 2.27160784387858, "BREXPIPRAZOLE": 9.149609123764314, "BRINTELLIX": 3.0106942767589344, "CANCIDAS": 1.5310261012565636, "CAPRELSA": 42.41802507870104, "CARFILZOMIB": 1.1762967979558985, "COBIMETINIB": 3.440272932233699, "CORTICOSTEROIDS": 6.182824181576268, "COTELLIC": 2.1219654170119924, "DASATINIB": 1.6252952488851318, "DELAMANID": 39.073722321132486, "DELTYBA": 64.12384229545944, "DENOSUMAB": 11.24752656752983, "DESLORATADINE": 2.6230803387564854, "DEXMEDETOMIDINE": 3.3765495905314906, "DOFETILIDE": 38.93381479128505, "DULOXETINE": 2.73235471006202, "EMTRICITABINE": 1.871069578384328, "ENZALUTAMIDE": 1.7821402721436823, "ESOMEPRAZOLE": 2.201830748755588, "FULVESTRANT": 1.765682697073645, "GENVOYA": 2.024462664843837, "GLIVEC": 1.47807410780375, "IBUPROFEN": 2.0300663838612167, "INVEGA": 4.219308430202351, "IRBESARTAN": 3.7484294569976098, "IRESSA": 1.5693413861358263, "IRON": 3.152296753828457, "IVABRADINE": 14.944706497890229, "KALETRA": 6.959521425242634, "KEPPRA": 1.101565333118396, "KETOCONAZOLE": 4.789970606935725, "KISQALI": 34.01419135788273, "KYPROLIS": 2.5183917968040723, "LATUDA": 1.1627746051665728, "LENVIMA": 1.6951884756351867, "LEVETIRACETAM": 1.4302434286670664, "LEVOFLOXACIN": 9.18930901746827, "LOPINAVIR": 19.46770830627825, "MELATONIN": 4.01986463270565, "MEMANTINE": 3.4258917463075487, "MIDAZOLAM": 2.3417716922055867, "MIDOSTAURIN": 12.564313883995508, "MIMPARA": 2.017175315794044, "MULTAQ": 9.647649004262677, "NALOXONE": 13.492775247763587, "NILOTINIB": 9.12100456628418, "NORVIR": 1.0041469800758591, "NOXAFIL": 12.799748002865092, "OLANZAPINE": 7.857470223806124, "OLYSIO": 1.2752300813828392, "OSELTAMIVIR": 3.324427897010496, "OSIMERTINIB": 5.64770763476954, "PANTOPRAZOLE": 1.5762773310013904, "POSACONAZOLE": 3.563099572978805, "PREGABALIN": 1.5564436617281827, "PRETOMANID": 22.08900263208421, "PROPRANOLOL": 3.345589616807365, "RANEXA": 5.54930487941373, "RANOLAZINE": 14.392136698131354, "REMDESIVIR": 2.6444020657148237, "REYATAZ": 3.1487332357555164, "RIBOCICLIB": 19.127989752419097, "RISPERIDONE": 1.5012518839941964, "RYDAPT": 7.2936575098600755, "SCEMBLIX": 10.286915074612551, "SIGNIFOR": 7.4799445025262035, "SIRTURO": 112.0765038457217, "SPIRONOLACTONE": 2.033134358926629, "SPRYCEL": 3.005192238850612, "SUNITINIB": 16.8902170475667, "SYCREST": 2.6684345088925614, "TACROLIMUS": 3.153313608304094, "TAGRISSO": 14.629520935685772, "TASIGNA": 12.345776215008677, "TIGECYCLINE": 4.713881439747022, "TIKOSYN": 10.489360458467567, "TOVIAZ": 1.1524660205376098, "TRISENOX": 87.4483537985836, "VALSARTAN": 1.6090921649788132, "VANDETANIB": 28.364739606665385, "VEKLURY": 2.251513952628348, "VEMURAFENIB": 10.930756011241996, "VFEND": 4.520858977192903, "VIMPAT": 1.1580642224942528, "VORICONAZOLE": 7.561895174704058, "VORTIOXETINE": 6.587641231327645, "VOTRIENT": 1.3180731943958237, "XALKORI": 7.204074579501508, "XEPLION": 6.694905452022044, "ZELBORAF": 6.043463166343853, "ZYPREXA": 4.594499426067631, "null": 2.521173385843104}
\ No newline at end of file
+{"TAMIFLU": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2733.json
index bd8c1d6e23f..69b9d91f103 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2733.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2733.json
@@ -1 +1 @@
-{"null": 3.123254254014722}
\ No newline at end of file
+{"STELARA": 4.656332933267311, "null": 1.9305273911390015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2734.json
index d348bff2409..5c82226f7cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2734.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2734.json
@@ -1 +1 @@
-{"null": 1.7813829783242132}
\ No newline at end of file
+{"null": 1.3183930208231711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2735.json
index 0f601593120..a6e09f54cd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2735.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2735.json
@@ -1 +1 @@
-{"null": 1.9147619606564508}
\ No newline at end of file
+{"CLADRIBINE": 1951.404557212722, "null": 0.3411798989533218}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2736.json
index ec006b62496..6cdf42a530a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2736.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2736.json
@@ -1 +1 @@
-{"null": 2.858006846205243}
\ No newline at end of file
+{"LEVOFLOXACIN": 11.967014628111576, "null": 2.796541717632211}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2737.json
index 9288627271a..8b6061437a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2737.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2737.json
@@ -1 +1 @@
-{"BRIDION": 22.268281228545906, "CICLOSPORIN": 2.116441239323388, "CLOPIDOGREL": 4.597917388514503, "FENTANYL": 20.669784717168607, "KEYTRUDA": 1.0946434350368996, "null": 2.987554282438776}
\ No newline at end of file
+{"ABILIFY": 0.7533428344822213, "ADALIMUMAB": 0.2883812347492796, "AFINITOR": 1.0588511728892145, "ALEMTUZUMAB": 1.674128509764968, "AMIKACIN": 19.65318733007692, "ASPARAGINASE": 29.462351886900432, "BLINCYTO": 24.28982063661031, "BUSULFAN": 8.374007657454358, "CARMUSTINE": 11.386443904039048, "CELLCEPT": 1.6726553385588667, "CICLOSPORIN": 2.1444346334092157, "CIMZIA": 0.2724642734382284, "CLOPIDOGREL": 0.6278953800370546, "COMIRNATY": 0.0131145195962492, "CUBICIN": 7.431467874360369, "CYTARABINE": 7.351137413831356, "DEXAMETHASONE": 4.550127804635343, "DIFICLIR": 189.13680161789384, "DOXORUBICIN": 2.1838694768949174, "EFAVIRENZ": 7.609831456444077, "ELIQUIS": 0.1974046473607897, "ENTYVIO": 1.5229767078514278, "ESOMEPRAZOLE": 3.757907576573632, "EXJADE": 1.7021909661521777, "FIDAXOMICIN": 52.24160712664252, "GANCICLOVIR": 4.737792072897808, "HUMIRA": 0.6812406441333528, "IBRANCE": 0.4691659496460205, "INVANZ": 75.26220815004392, "IRINOTECAN": 2.4538811677835928, "JANUVIA": 1.4745268235522475, "KEPPRA": 0.5360221165881618, "KEYTRUDA": 0.8724670505207024, "KYMRIAH": 5.132989245704502, "LANTUS": 0.1985507571395738, "LEVOFLOXACIN": 7.427462400498184, "MELPHALAN": 8.944070256971859, "METHOTREXATE": 0.9748616858105802, "MYCOPHENOLATE": 2.867416718776701, "NEXAVAR": 0.4915218394369445, "NOT": 6.956412937382509, "NOXAFIL": 6.237991797570545, "OPDIVO": 0.8215695461955835, "OPSUMIT": 1.785152753145103, "PANTOPRAZOLE": 1.810615510050458, "RITUXIMAB": 1.6964826691547576, "SOLIRIS": 2.1275989735741425, "SPIKEVAX": 0.0273253960586909, "SPRYCEL": 1.1728157777853765, "STELARA": 0.4123435750544909, "SUNITINIB": 13.851988879341262, "SUTENT": 0.4876534738960365, "TAMIFLU": 1.248812116719031, "TOBRAMYCIN": 7.330993510280246, "TYGACIL": 59.760479895785295, "XELJANZ": 0.7765592751981027, "XTANDI": 0.6828775489778897, "YESCARTA": 2.965516752817785, "null": 2.8815849651448837}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2738.json
index c4bf5b20349..a0e8a6f1415 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2738.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2738.json
@@ -1 +1 @@
-{"ABACAVIR": 1.8722099021355612, "ARIPIPRAZOLE": 2.22761095216364, "BRIDION": 13.92436478598933, "CLOPIDOGREL": 4.074587902460815, "COMIRNATY": 1.0307710292310903, "ENTRESTO": 3.4663151846904494, "EVEROLIMUS": 24.214403426721475, "FENTANYL": 9.770150398323102, "IBUPROFEN": 6.121215868968591, "MIDAZOLAM": 11.507383922643507, "OLANZAPINE": 1.6837550603606883, "PLAVIX": 1.3037473468437493, "TICAGRELOR": 6.6434971709886135, "null": 2.168250195313933}
\ No newline at end of file
+{"ADALIMUMAB": 0.5268292657639131, "ADEMPAS": 3.517549486517138, "AFINITOR": 1.6636054078277118, "AIMOVIG": 0.6471435415542259, "ALEMTUZUMAB": 5.041782532279188, "AMIKACIN": 4.058652063326903, "ARAVA": 0.3665384173187344, "ASPARAGINASE": 5.586361099615156, "ATRIPLA": 0.2270225716428395, "AUBAGIO": 1.277427900183397, "AZACITIDINE": 4.311910718609019, "AZATHIOPRINE": 4.469714373615526, "BENLYSTA": 1.3809988449595418, "BLINATUMOMAB": 11.4918429646483, "BORTEZOMIB": 5.863781155191644, "BOSULIF": 2.628549378272279, "BUDESONIDE": 0.3318256406407997, "BUSULFAN": 7.292770334992229, "BYETTA": 0.7237052991075783, "CELLCEPT": 1.6892754878149754, "CICLOSPORIN": 1.5696991676717047, "CIMZIA": 3.002213175735472, "CLADRIBINE": 6.050339868115159, "CLOPIDOGREL": 0.3151634612166718, "COMIRNATY": 0.0087988769904922, "COSENTYX": 0.7642316148696351, "CUBICIN": 2.3772193634066983, "CYTARABINE": 5.763065910988553, "DAPTOMYCIN": 7.959074553631679, "DEXAMETHASONE": 1.1348693040383393, "DIFICLIR": 312.5575424723945, "DOCETAXEL": 1.313331659308216, "DOXORUBICIN": 3.1713530572825075, "ELIQUIS": 0.6415428456778273, "ENBREL": 0.412693398237241, "ENTYVIO": 12.695095164684687, "ERTAPENEM": 35.99342939746824, "ESBRIET": 1.2609149795664665, "EXJADE": 1.0028167100638017, "FASLODEX": 1.070738458527531, "FENTANYL": 0.8435042081770032, "FIDAXOMICIN": 919.7556850050524, "FILGRASTIM": 9.345076437717816, "HIZENTRA": 3.739421721930439, "HUMALOG": 0.4567569577783193, "HUMIRA": 2.879046603471997, "IBRANCE": 1.4491843475690442, "IBUPROFEN": 2.937779657568792, "INFLECTRA": 16.373010926433295, "INFLIXIMAB": 7.677456660242504, "INLYTA": 0.8936748279659908, "INVANZ": 24.28068171944017, "IPILIMUMAB": 2.508613837488696, "IRINOTECAN": 2.9131686399464622, "JANUVIA": 0.7509511177609286, "KEYTRUDA": 0.6005343019798188, "LANTUS": 0.3904563358980751, "LEFLUNOMIDE": 5.54246275248921, "LEVOFLOXACIN": 5.885202378777908, "MELPHALAN": 7.037641393385618, "METHOTREXATE": 1.6794025877309129, "MYCOPHENOLATE": 2.2562725367629133, "NEULASTA": 1.8919123672199023, "OMALIZUMAB": 0.7544063902405306, "OPSUMIT": 3.123369209915656, "PLAVIX": 0.3867741160068383, "RAPAMUNE": 2.51916040141848, "REMICADE": 3.744381497287317, "REVATIO": 2.1450567238969853, "RINVOQ": 2.594368059909305, "RITUXIMAB": 1.080372517215803, "SIMPONI": 1.6157786983707134, "SOLIRIS": 3.511297795772576, "SPIKEVAX": 0.0238201181042735, "SPINRAZA": 2.439469699591208, "SPRYCEL": 2.301920483489054, "STELARA": 5.046323547565862, "SUTENT": 0.5038750696447651, "TELMISARTAN": 6.492767959112053, "TOZINAMERAN": 0.0981623687542719, "TRACLEER": 1.995069853685904, "VOTRIENT": 1.6647388941320698, "XELJANZ": 4.693789020244809, "XOLAIR": 0.8216947561116548, "XTANDI": 1.5284775582171328, "YESCARTA": 3.146396404017156, "ZINPLAVA": 798.4585521068532, "ZOSTAVAX": 0.3194660882511145, "null": 1.6341115859131827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2739.json
index 6ef4624d6cb..ee192127fe6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2739.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2739.json
@@ -1 +1 @@
-{"null": 2.7538219158768213}
\ No newline at end of file
+{"null": 1.2235218531283787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/274.json
index 3068b90ca75..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/274.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/274.json
@@ -1 +1 @@
-{"ABILIFY": 1.7283428371298684, "ARIPIPRAZOLE": 12.2509768347496, "ATAZANAVIR": 6.645046683104713, "BEDAQUILINE": 9.479007261780232, "BENZODIAZEPINE": 22.97173161425185, "BUPRENORPHINE": 25.525510957673585, "CHAMPIX": 3.6238319326479775, "CYMBALTA": 2.2073722859353646, "DELAMANID": 25.62701757663471, "KEPPRA": 2.443296946676045, "OLANZAPINE": 1.6667914281998424, "PEGINTRON": 2.522592023484853, "PREGABALIN": 11.517031584299016, "SUBOXONE": 50.49009616089236, "ZYPREXA": 2.897917832979334, "null": 2.790836913623908}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2740.json
index 314d08b4d2e..49239de9fca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2740.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2740.json
@@ -1 +1 @@
-{"null": 2.059807064143012}
\ No newline at end of file
+{"CYTARABINE": 6.583859114937175, "DEXAMETHASONE": 3.274504147349349, "INVANZ": 354.08815233641167, "null": 4.9076120042046485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2741.json
index 4d17ebfdf82..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2741.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2741.json
@@ -1 +1 @@
-{"null": 1.4303389403425195}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2742.json
index af72c62c0a5..7069df4563a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2742.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2742.json
@@ -1 +1 @@
-{"FENTANYL": 4.756330496655121, "GARDASIL": 6.768431223725661, "null": 2.080117867805221}
\ No newline at end of file
+{"ANAKINRA": 167.5243806954391, "PEGASYS": 5.540838200373807, "null": 0.6684169885173621}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2743.json
index faa3d107191..8c727ca70c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2743.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2743.json
@@ -1 +1 @@
-{"CUBICIN": 66.05628602373844, "FENTANYL": 16.028168028548233, "null": 2.2871112423576205}
\ No newline at end of file
+{"COMIRNATY": 0.4918657961524224, "GARDASIL": 1.8997837268293296, "KEPPRA": 3.167213372201454, "RITUXIMAB": 5.994646281394334, "SPIKEVAX": 0.3652739659515276, "TELMISARTAN": 44.01255712891343, "TOZINAMERAN": 1.1497505583149918, "VAXZEVRIA": 0.6831654061383007, "null": 1.2725553412431077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2744.json
index 7a0c3a2059e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2744.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2744.json
@@ -1 +1 @@
-{"null": 3.4027766816184544}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2745.json
index dfd8920bd90..9651200627c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2745.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2745.json
@@ -1 +1 @@
-{"BEDAQUILINE": 21.26716683437778, "CLOPIDOGREL": 1.8412078331697992, "ENTRESTO": 6.10130576216825, "FENTANYL": 4.420116069736779, "FINGOLIMOD": 419.3855741897945, "OLANZAPINE": 3.395041870017632, "null": 2.711743963238393}
\ No newline at end of file
+{"AIMOVIG": 4.14003751531551, "APIXABAN": 1.776447094528251, "BUPRENORPHINE": 7.775858848599443, "BYDUREON": 5.692104476120318, "COMIRNATY": 1.0276157325883095, "DEXAMETHASONE": 1.387832921243467, "GARDASIL": 0.6922361205363292, "KEPPRA": 0.7988072527725822, "OCRELIZUMAB": 5.214815332736182, "SODIUM": 93.0829645908044, "SPIKEVAX": 1.0497916565901582, "STELARA": 1.3658186608519354, "TOZINAMERAN": 4.656933853030841, "VAXZEVRIA": 6.528785624712481, "null": 0.2764869721450106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2746.json
index 0fda3532312..059e40c7aec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2746.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2746.json
@@ -1 +1 @@
-{"SPIRONOLACTONE": 125.96764329885842, "null": 2.727197458792604}
\ No newline at end of file
+{"null": 4.8401644167385305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2747.json
index 54ee64f2929..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2747.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2747.json
@@ -1 +1 @@
-{"null": 1.910040633304925}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2748.json
index eb3aafdad82..4f7cb8d6fae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2748.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2748.json
@@ -1 +1 @@
-{"null": 6.8031563798956105}
\ No newline at end of file
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2749.json
index 3fe7677bac6..e21f11cc8bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2749.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2749.json
@@ -1 +1 @@
-{"ABILIFY": 1.0058831591886626, "AVANDIA": 1.4998696401457332, "BRILIQUE": 4.66264249765424, "COMBIVIR": 2.6318488674283325, "CYTARABINE": 1.3546282338283595, "ENTRESTO": 2.6627722430024354, "EXFORGE": 1.424074923205868, "FENTANYL": 4.748316750827945, "IBUPROFEN": 2.0865737765901438, "KALETRA": 2.806224200059849, "MIDAZOLAM": 3.972165131935523, "MULTAQ": 3.2559949144933698, "OLANZAPINE": 3.819595401994779, "SPIRONOLACTONE": 6.0407738948376, "TASIGNA": 1.1751607610843096, "TELMISARTAN": 4.918461170090918, "ZOSTAVAX": 1.0609010827045573, "ZYPREXA": 2.3059323158623317, "null": 2.135463740002004}
\ No newline at end of file
+{"APIXABAN": 212.5544576941761, "BUDESONIDE": 90.7318913725346, "ELIQUIS": 15.081717727929217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/275.json
index e154a481117..3cd695dc839 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/275.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/275.json
@@ -1 +1 @@
-{"BRINTELLIX": 6.146183776793818, "BUPRENORPHINE": 44.68683468712696, "CHAMPIX": 28.7329509594068, "VIAGRA": 5.777872679256765, "null": 3.836258269526734}
\ No newline at end of file
+{"ALISKIREN": 818.1305267323465, "CHAMPIX": 2.0974310618034138, "COMIRNATY": 0.4774142546225273, "ESOMEPRAZOLE": 15.266279122472952, "GARDASIL": 1.3715341898666222, "GLYCOPYRRONIUM": 427.4883404179413, "IRBESARTAN": 11.864618588958349, "KEPPRA": 1.5826845968545404, "SPIKEVAX": 0.2382893688419875, "VAXZEVRIA": 0.0919547747836319, "ZOSTAVAX": 30.96601445600161, "null": 0.5947160840793438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2750.json
index d1ebeed173f..bb80d4af192 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2750.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2750.json
@@ -1 +1 @@
-{"AVANDIA": 4.942959132239823, "null": 3.2273844410884927}
\ No newline at end of file
+{"null": 1.8945431622751896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2751.json
index ad3e6ba9a7d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2751.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2751.json
@@ -1 +1 @@
-{"null": 1.2326483963287242}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2752.json
index 09f77274345..815c3fd2bb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2752.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2752.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4480053479744075, "SPIKEVAX": 17.320045858299704}
\ No newline at end of file
+{"null": 2.457594580105288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2753.json
index 152a57cc0fd..4db056d14a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2753.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2753.json
@@ -1 +1 @@
-{"BUDESONIDE": 6.127680521598452, "null": 2.630327964366432}
\ No newline at end of file
+{"null": 0.502161135947256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2754.json
index 214c1b1fbb7..687f4cc5aed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2754.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2754.json
@@ -1 +1 @@
-{"SPIKEVAX": 3.5556317021451456}
\ No newline at end of file
+{"null": 0.7371811038850543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2755.json
index eebf44b100f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2755.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2755.json
@@ -1 +1 @@
-{"ASPARAGINASE": 13.85665644314401, "CICLOSPORIN": 2.8085093446800258, "COMBIVIR": 11.393316842986644, "FENTANYL": 4.992944654996113, "GARDASIL": 1.4752046344256566, "HYDROCORTISONE": 6.242262733660415, "KEPPRA": 7.726045408301603, "LEVETIRACETAM": 20.781853516182707, "MIDAZOLAM": 16.373418698651413, "OLANZAPINE": 4.943405819363087, "SODIUM": 87.68644476337025, "VIMPAT": 9.860301414622144, "ZYPREXA": 5.525788423732841, "null": 3.1477598554496407}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2756.json
index 1e000a3134e..9951e487672 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2756.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2756.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 34.006751629964945, "null": 1.0952868191683736}
\ No newline at end of file
+{"null": 2.493281226716725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2757.json
index 37389b26c40..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2757.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2757.json
@@ -1 +1 @@
-{"AFINITOR": 1.4276010863883306, "ALISKIREN": 4.600457955448892, "AMIKACIN": 6.020200806806434, "AMINOSALICYLIC": 6.448536023567732, "ASPARAGINASE": 1.575984880477994, "AVASTIN": 1.1430471368848836, "BEDAQUILINE": 13.418130212401026, "BENZODIAZEPINES": 39.838417985701255, "BEVACIZUMAB": 1.3768506091426882, "CAPECITABINE": 5.072774054331535, "CICLOSPORIN": 1.9812127582904149, "CLOPIDOGREL": 1.1428213649120746, "COAPROVEL": 5.665841999216865, "CYTARABINE": 1.8358826478377108, "DELAMANID": 12.277859677625385, "DEXAMETHASONE": 1.3761411336118596, "DEXMEDETOMIDINE": 19.769814507836617, "DOCETAXEL": 1.476472053311862, "DULOXETINE": 5.166635126867194, "ENTRESTO": 1.316661417274162, "EVEROLIMUS": 6.312003765456354, "EXJADE": 1.4796146361236922, "IBUPROFEN": 1.206468024592776, "IRBESARTAN": 3.688027549686892, "JANUMET": 1.2556172944139714, "JANUVIA": 1.5450886050673804, "JARDIANCE": 2.0183706471109675, "KALETRA": 2.969413682696282, "KEYTRUDA": 2.2885065396374, "KYMRIAH": 2.997902569153828, "LENVIMA": 2.8846279584939047, "LEVETIRACETAM": 2.140458865779392, "LEVOFLOXACIN": 1.5368878210883188, "LYRICA": 1.06024105691322, "MEKINIST": 2.3677905708133062, "MICARDISPLUS": 16.370008908521847, "NEULASTA": 1.677987643546457, "NEXAVAR": 1.5273822812396285, "OPSUMIT": 1.124772596612991, "PANTOPRAZOLE": 5.11357497549414, "SOMATROPIN": 9.670530122271732, "SPIRONOLACTONE": 4.82379326386435, "SUTENT": 1.1951002756179396, "SYNAGIS": 2.367566494330382, "TACROLIMUS": 11.05953188385152, "TRULICITY": 1.3405869173836529, "VORICONAZOLE": 3.933001171890683, "VOTRIENT": 2.1646289537605106, "XYREM": 7.033362324740189, "ZYPREXA": 1.6924456936315118, "null": 1.9264932545501543}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2758.json
index 624170e33ad..8e6fdff5c88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2758.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2758.json
@@ -1 +1 @@
-{"null": 1.731601702195374}
\ No newline at end of file
+{"LIXIANA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2759.json
index 161e98955fc..ffed2e44063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2759.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2759.json
@@ -1 +1 @@
-{"DULOXETINE": 956.7971746578976}
\ No newline at end of file
+{"null": 0.8953782293383834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/276.json
index a317f9a8b5b..f455c51e916 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/276.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/276.json
@@ -1 +1 @@
-{"CHAMPIX": 13.012596496332264, "GARDASIL": 3.997143694867675, "null": 2.379010938841997}
\ No newline at end of file
+{"ABACAVIR": 4.237392635996414, "ABATACEPT": 61.30277575283727, "ADALIMUMAB": 48.80978239367883, "AMINOSALICYLIC": 32.407784685791746, "APREMILAST": 113.06969794229198, "ARAVA": 3.5715678642549387, "CERTOLIZUMAB": 47.68692017314798, "CHAMPIX": 2.168077461303479, "CICLOSPORIN": 0.5271864566024823, "COMIRNATY": 0.0731848322976889, "COSENTYX": 2.1066981637073896, "ENTYVIO": 1.6504502958561562, "GARDASIL": 0.5033956100746612, "MYCOPHENOLATE": 5.500815660546509, "PEGINTRON": 0.969650922184802, "RITUXIMAB": 1.5884289874235595, "SPIKEVAX": 0.0430567584238786, "VAXZEVRIA": 0.0428611978756593, "ZOSTAVAX": 0.898077766892479, "null": 0.1780219842854792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2760.json
index 5f2968f6389..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2760.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2760.json
@@ -1 +1 @@
-{"ELIQUIS": 36.11920507529975}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2761.json
index b2efebd1e31..da631856854 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2761.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2761.json
@@ -1 +1 @@
-{"null": 4.826380696809855}
\ No newline at end of file
+{"null": 2.9900624652399084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2762.json
index 50c0cf70a4b..ac4b2b8a91d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2762.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2762.json
@@ -1 +1 @@
-{"null": 6.854608928972396}
\ No newline at end of file
+{"APIXABAN": 132.652584400636, "BUDESONIDE": 54.20292999250894, "null": 0.6416679713404415}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2763.json
index 1ade76a34cb..9a43f79ce02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2763.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2763.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1986052270756726, "ELIQUIS": 12.265326190051605}
\ No newline at end of file
+{"null": 0.6180072909783187}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2764.json
index 93bae675d20..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2764.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2764.json
@@ -1 +1 @@
-{"AVANDIA": 3.4631106045619933, "CLOPIDOGREL": 5.853511918684582, "DEXAMETHASONE": 2.025825239845729, "ELIQUIS": 48.89697717426432, "LIXIANA": 25.81648769626895, "NOVOSEVEN": 27.60877028983399, "NPLATE": 5.517723805720633, "PLAVIX": 4.020423737633144, "PRADAXA": 19.751723426223187, "XARELTO": 9.72745224184898}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2765.json
index 29ecb731523..97564b1ee72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2765.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2765.json
@@ -1 +1 @@
-{"APIXABAN": 1.075641033723137, "AVASTIN": 5.611722486720088, "BEDAQUILINE": 3.407040151654625, "BEVACIZUMAB": 5.387428116240368, "BLINATUMOMAB": 18.088366983540254, "CLOPIDOGREL": 1.194378361688255, "COVID19": 1.6936611955442051, "CUBICIN": 7.065997068771261, "CYTARABINE": 1.1331205631898225, "DEXAMETHASONE": 3.7394650602255, "ELIQUIS": 5.629646065321832, "ENOXAPARIN": 7.1293822282274935, "EVISTA": 46.02814311929044, "FASLODEX": 2.977496106906006, "FENTANYL": 1.0007163227860534, "FORSTEO": 1.5555879560765962, "HUMAN": 5.035406269515918, "JAKAVI": 2.1243556744546503, "METHOTREXATE": 1.0531865396164812, "NOVOSEVEN": 33.62984673505934, "NPLATE": 19.10742456150288, "PEGFILGRASTIM": 21.819417677679464, "PROTELOS": 10.693648234357148, "RINVOQ": 4.760004513842372, "ROACTEMRA": 1.5552085756872054, "THALIDOMIDE": 9.526398187641204, "TOZINAMERAN": 1.529523954778664, "VAXZEVRIA": 1.1530266017148216, "XELJANZ": 1.2696092548086966, "ZYPREXA": 1.463707694964825}
\ No newline at end of file
+{"CLOPIDOGREL": 4.806386963977912, "COMIRNATY": 0.1284520208783033, "TRACLEER": 7.406670897859708, "VAXZEVRIA": 0.1840753093090149, "null": 2.1122464914307564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2766.json
index d50fc061db2..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2766.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2766.json
@@ -1 +1 @@
-{"ELIQUIS": 4.461745988823241}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2767.json
index 2cb59ec5823..479b23e04a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2767.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2767.json
@@ -1 +1 @@
-{"ASPARAGINASE": 10.76203789058176, "AVASTIN": 12.98147081650123, "BEVACIZUMAB": 7.7124713056717935, "BUDESONIDE": 5.155983529678085, "ELIQUIS": 10.94544583467757, "ENOXAPARIN": 21.32796842663528, "EVISTA": 66.84597846085978, "NOVOSEVEN": 26.891865923093462, "OLANZAPINE": 15.407549221040592, "PEGASPARGASE": 191.89311462798915, "RINVOQ": 15.404675622541552, "XELJANZ": 2.696699270163605}
\ No newline at end of file
+{"ANGIOX": 6112.261523717118, "null": 1.043158664015366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2768.json
index 4ff52f988fb..b113c7e696c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2768.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2768.json
@@ -1 +1 @@
-{"IBUPROFEN": 7.789073029268174, "NUCALA": 7.68482735417072, "OPSUMIT": 15.424324189258108, "null": 3.139681335515045}
\ No newline at end of file
+{"CLOPIDOGREL": 11.44061908335318, "ENOXAPARIN": 28.389420293129294, "LEVOFLOXACIN": 2.2335253529142887, "PLAVIX": 3.3576344535600677, "VAXZEVRIA": 0.1713039869384491, "null": 4.073104517790355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2769.json
index 9c2b6272c77..dc6714ea279 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2769.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2769.json
@@ -1 +1 @@
-{"VOTRIENT": 16.49954482242419, "null": 6.326282897596922}
\ No newline at end of file
+{"null": 1.8638704636180328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/277.json
index acf7d8dca6d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/277.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/277.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 5.001489980624515, "BEDAQUILINE": 16.803271022461573, "BUPRENORPHINE": 5.018914508430233, "BUVIDAL": 65.59706160161677, "CHAMPIX": 6.930295939797584, "CYMBALTA": 2.505478527734472, "DELAMANID": 54.9834279945252, "FENTANYL": 9.248621321884372, "IBUPROFEN": 3.741636567455613, "KEPPRA": 1.5258836775329565, "PREGABALIN": 19.3063797893705, "SUBOXONE": 2.788527834969622, "ZYPREXA": 4.09410588870549, "null": 3.4895729379752813}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2770.json
index bd1253b1c0d..49d55460cdd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2770.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2770.json
@@ -1 +1 @@
-{"ABILIFY": 4.240201602179114, "ARIPIPRAZOLE": 1.744514972566538, "ASPARAGINASE": 3.212743310736533, "BENLYSTA": 2.820879035883171, "BEXTRA": 17.042091928144742, "BIKTARVY": 2.010543519809912, "BRINTELLIX": 1.8652985107138944, "BRIVIACT": 11.873902606605606, "BUPRENORPHINE": 1.766814332569129, "CHAMPIX": 11.24919960107046, "CYMBALTA": 2.606191721056698, "DULOXETINE": 1.5699658275430115, "ELLAONE": 4.808722830383373, "ENBREL": 1.0742770870800933, "EXFORGE": 1.5822862077678217, "FENTANYL": 4.022202891379808, "FYCOMPA": 3.707431638699628, "GARDASIL": 1.0403727544745316, "HYDROCORTISONE": 3.261860886260139, "IBRANCE": 2.572364353113036, "IBUPROFEN": 1.848713955497421, "INCIVO": 2.001472889594369, "INVEGA": 11.593336288808644, "JANUMET": 1.8434754930334931, "KAFTRIO": 3.638862564834876, "KEPPRA": 5.790914978456578, "LATUDA": 2.8932844919848923, "LEVETIRACETAM": 2.2513120162268887, "LYRICA": 2.1821146092635977, "MEPOLIZUMAB": 1.073022160191676, "OLANZAPINE": 1.2135495032178991, "ORKAMBI": 5.099836298815795, "PEGASYS": 2.4549170492396573, "RIBAVIRIN": 1.8258705068048544, "RISPERIDONE": 6.337126418785396, "SIFROL": 4.114688556790301, "SILDENAFIL": 2.3232156438278952, "SUBOXONE": 1.3055955529137602, "SUTENT": 1.163005687915054, "TAMIFLU": 1.015501101790476, "TOVIAZ": 1.637884778090844, "TRODELVY": 8.24960300324811, "XOLAIR": 1.5308672759311206, "ZYPREXA": 2.3817556488502776, "null": 2.183317074436155}
\ No newline at end of file
+{"ALEMTUZUMAB": 0.9361336996232036, "ANGIOX": 20.283819701341173, "APIXABAN": 0.4135500732812514, "ARAVA": 0.3452273005280097, "ARIXTRA": 7.904383536646639, "ASPARAGINASE": 7.293560142298391, "AVANDIA": 0.4654392297605306, "AZATHIOPRINE": 1.040845293475584, "BLINATUMOMAB": 16.627766824131818, "BRILIQUE": 0.9850115139725238, "BRIVARACETAM": 11.621960265885397, "BUDESONIDE": 0.3715943499601045, "BUPRENORPHINE": 0.5206845564859554, "BUSULFAN": 1.9685405099314333, "BYETTA": 0.6514903674564997, "CELLCEPT": 0.7311460818702897, "CICLOSPORIN": 0.8066822597887497, "CLOPIDOGREL": 4.425872945623838, "COMIRNATY": 0.3885421975174963, "CYMBALTA": 0.257456209770382, "CYTARABINE": 3.193760208366643, "DEXAMETHASONE": 1.6163778354466432, "ELIQUIS": 1.7058993393195696, "ENOXAPARIN": 13.738335032578778, "EXJADE": 1.1364402455423697, "EXVIERA": 4.279825938909228, "FENTANYL": 2.2437579666205583, "FILGRASTIM": 2.1561617411715326, "FORSTEO": 0.3000381442172042, "GANCICLOVIR": 2.730106209427165, "GARDASIL": 0.3170320672384066, "IBRANCE": 0.3219512882724846, "IBUPROFEN": 2.202746257509168, "IRON": 3.467855360613948, "JAKAVI": 0.7872843102579675, "JANUMET": 0.9120364430939626, "JANUVIA": 1.2810720116118066, "KEPPRA": 1.227057379551165, "KEYTRUDA": 0.173499588865296, "KYMRIAH": 18.811886412506823, "LAMIVUDINE": 2.989894582463382, "LANTUS": 0.2292064825894182, "LEVETIRACETAM": 0.7081072894064967, "LEVOFLOXACIN": 3.2867058664921647, "LONSURF": 1.366699638496432, "MEKINIST": 1.0010271060765117, "MULTAQ": 2.6557711681417056, "NPLATE": 0.9991726312241136, "OLANZAPINE": 0.258506219225302, "ONCASPAR": 20.76582172902712, "OPDIVO": 0.7301127665954087, "OPTIMARK": 0.5144029947832681, "PEGASPARGASE": 15.246538514936956, "PEGASYS": 1.0433053576474374, "PLAVIX": 5.126538035279253, "PRADAXA": 29.09194849269363, "PRAXBIND": 26.50508909634756, "ROACTEMRA": 1.4256687805178567, "SOLIRIS": 0.7800449240443632, "SPIKEVAX": 0.2288460442026519, "SPIRONOLACTONE": 4.444699785685563, "STIVARGA": 0.7886737483192686, "SUTENT": 0.423713206208919, "TAMIFLU": 1.3526034444151136, "TIGECYCLINE": 13.326420063187022, "TOZINAMERAN": 0.3729578892262143, "TRACLEER": 1.5209670908743684, "VAXZEVRIA": 0.5420332376847323, "VFEND": 1.2380556655034878, "VOTRIENT": 0.511175935779659, "XARELTO": 13.740802257186036, "XELJANZ": 0.3224557880779267, "YESCARTA": 2.284966711588554, "ZOSTAVAX": 0.7298546495278248, "ZYPREXA": 0.2499670228777324, "null": 1.8907832350971616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2771.json
index c7a4da19eff..c629388c705 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2771.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2771.json
@@ -1 +1 @@
-{"null": 2.037812422706561}
\ No newline at end of file
+{"KALETRA": 12.568011215855671, "LACOSAMIDE": 26.323474854741374, "null": 7.633651043291932}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2772.json
index 912183b128f..e85d53e5f13 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2772.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2772.json
@@ -1 +1 @@
-{"ABLAVAR": 161.85208465362794, "ACETAMINOPHEN/OXYCODONE": 11.540852615818826, "ATRIPLA": 45.88186816707796, "BONVIVA": 1.6359948185263578, "BORTEZOMIB": 1.0076102891502814, "BUDESONIDE": 1.7814437853748897, "BUPIVACAINE": 1.0397924718847906, "BUPRENORPHINE": 1.927682197991171, "CIALIS": 9.361178518236857, "CONTRAST": 4.303460161890472, "INVEGA": 1.8990244487402523, "KALETRA": 1.5780199607134182, "LATUDA": 1.0659590791837863, "NALOXONE": 2.081520108533881, "OCRELIZUMAB": 1.8154271277891625, "OPTIMARK": 16.79590190336354, "STRIBILD": 31.391290817044823, "TASIGNA": 7.998916420866814, "TRUVADA": 30.04732525117182, "VIREAD": 18.20795610370266, "ZOSTAVAX": 1.1406780535341707}
\ No newline at end of file
+{"COMIRNATY": 0.3237062711585988, "null": 2.1617190932420565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2773.json
index ca526a2196c..5f849eeaa0a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2773.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2773.json
@@ -1 +1 @@
-{"ABILIFY": 5.3245266242829, "BRINTELLIX": 8.21440193284497, "CHAMPIX": 9.420701779334095, "CYMBALTA": 5.28290688227006, "LATUDA": 13.5690236058716, "ZYPREXA": 7.611317837003887, "null": 3.421834528426761}
\ No newline at end of file
+{"STELARA": 7.618320442302831, "TRELEGY": 38.86176518309615, "XELJANZ": 10.41955380326084, "null": 0.4843168873506175}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2774.json
index ab4c58986f5..bd1f875751e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2774.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2774.json
@@ -1 +1 @@
-{"ACLIDINIUM": 35.37101046229918, "AFINITOR": 1.5063602423825946, "ANORO": 11.376633733691977, "BUDESONIDE": 6.315109050383659, "BUPRENORPHINE": 1.88549417338216, "BYETTA": 1.463172115383406, "CHAMPIX": 3.239620643938389, "DAPAGLIFLOZIN": 10.296138580794665, "DULOXETINE": 2.745102326447888, "ENBREL": 1.876899817620576, "ESBRIET": 1.8568522666754368, "FORSTEO": 2.021449684948051, "GLYCOPYRRONIUM": 11.609128297957133, "HUMALOG": 1.023025287667494, "HUMIRA": 1.6533901783536449, "IBUPROFEN": 1.4385429578303663, "INCRUSE": 6.027904355666179, "JANUMET": 5.181486564444433, "JANUVIA": 2.226606735218453, "KEYTRUDA": 1.8914659820852824, "LANTUS": 1.2384816988952767, "MEPOLIZUMAB": 6.745396259618143, "MICARDIS": 2.652561792605161, "MULTAQ": 4.678500418194788, "NUCALA": 4.2438251962019455, "OMALIZUMAB": 1.9823642638008456, "OPSUMIT": 1.7675837364680056, "PEGINTRON": 1.2308127133147555, "PEMBROLIZUMAB": 2.35432785203974, "RELVAR": 3.851770109581901, "REVATIO": 2.874387413230555, "RITUXIMAB": 1.294786686278892, "SEEBRI": 44.10726862854626, "SIMPONI": 2.100264673101695, "TRACLEER": 1.6746017257059138, "TRELEGY": 15.793052976067624, "ULTIBRO": 91.47627680376856, "XARELTO": 2.5593348205418978, "XOLAIR": 1.9627429534328693, "ZOSTAVAX": 3.4545367110704635, "null": 1.9151256165936308}
\ No newline at end of file
+{"AFINITOR": 5.59290840728708, "COMIRNATY": 0.9141844733549992, "FORSTEO": 10.42685379391597, "SPIKEVAX": 0.4283635297264677, "STELARA": 4.934060822368107, "TOZINAMERAN": 0.6358372481778055, "VAXZEVRIA": 0.46929535688119, "null": 0.7176429313130179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2775.json
index 5892a3bfd03..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2775.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2775.json
@@ -1 +1 @@
-{"FORXIGA": 77.30325469241441, "JARDIANCE": 58.75033885533983}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2776.json
index 5e773822854..ee640751074 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2776.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2776.json
@@ -1 +1 @@
-{"JARDIANCE": 66.83936493014743}
\ No newline at end of file
+{"null": 1.9001059167326195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2777.json
index 2fb926029f9..29baecd8167 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2777.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2777.json
@@ -1 +1 @@
-{"null": 4.406825286148448}
\ No newline at end of file
+{"BARACLUDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2778.json
index 5efaa3ed0c7..c364dca4349 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2778.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2778.json
@@ -1 +1 @@
-{"BEDAQUILINE": 21.85038051409052, "BORTEZOMIB": 50.05658309470043, "CICLOSPORIN": 2.68752793048808, "PEGASYS": 2.555324873058888, "ROACTEMRA": 12.175701292448736, "TOCILIZUMAB": 55.94500559302732}
\ No newline at end of file
+{"ABACAVIR": 79.09586377480385, "ADALIMUMAB": 21.00422222880301, "AIMOVIG": 4.915214421095718, "ANAKINRA": 2.7155507948375077, "APREMILAST": 15.557613018461916, "ARAVA": 2.7828400475922743, "CIMZIA": 2.611155419131056, "COMIRNATY": 0.0608382865498948, "ELIQUIS": 0.4222728653039038, "ENBREL": 3.14337702426625, "EXFORGE": 1.1232252787787211, "GARDASIL": 1.716937206047485, "HUMALOG": 1.8374455946857409, "HUMIRA": 2.6325244279893125, "KEPPRA": 0.4305716807190925, "KEYTRUDA": 0.2912678763453953, "LANTUS": 0.370953527979004, "NUCALA": 0.7451787257661658, "ORENCIA": 19.83955602045032, "PEGASYS": 0.1826345618617441, "PEGINTERFERON": 2.0860795364404403, "RITUXIMAB": 1.5014998525258605, "SIMPONI": 0.3883842984035788, "SPIKEVAX": 0.0259587149225806, "STELARA": 0.3091664518123154, "TOZINAMERAN": 0.1904983010889457, "VAXZEVRIA": 0.0383128362850423, "XELJANZ": 0.5912338987388291, "XOLAIR": 0.5571887030759087, "null": 1.2997293115790574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2779.json
index f145e3f1996..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2779.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2779.json
@@ -1 +1 @@
-{"ASPARAGINASE": 73.1880328359359, "ATRIPLA": 4.178229096643428, "null": 1.9021830230833523}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/278.json
index fb2188eaaed..08f81943bd7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/278.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/278.json
@@ -1 +1 @@
-{"null": 1.7928221752654427}
\ No newline at end of file
+{"null": 0.7945367150999303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2780.json
index eb19e4a4246..c615d798c06 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2780.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2780.json
@@ -1 +1 @@
-{"CELSENTRI": 133.48611436397306, "MMRVAXPRO": 6.144632904899591, "NEXAVAR": 6.288340282235854, "null": 2.4848376641965126}
\ No newline at end of file
+{"ABACAVIR": 0.4311588343333123, "ABILIFY": 1.577476337887187, "AERIUS": 1.370481325888683, "AFINITOR": 0.2090030337466736, "AIMOVIG": 1.1529522478093983, "ALEMTUZUMAB": 1.1259975514795508, "ALIMTA": 0.3327724051319516, "ALISKIREN": 11.167348743479756, "AMBROXOL": 76.04273014064854, "AMLODIPINE": 63.71014152609484, "ANAKINRA": 1.263732679615892, "APIDRA": 0.7585370346310537, "APIXABAN": 9.986329476837737, "ARAVA": 0.0636486310149543, "ARIPIPRAZOLE": 1.28038235689787, "ASPARAGINASE": 1.1303437700760035, "ATRIPLA": 0.1082961401321185, "AUBAGIO": 3.961541347446057, "AVAMYS": 0.4070249015044275, "AVANDIA": 0.1387261861535245, "AZILECT": 7.275579916835688, "BENLYSTA": 0.5417757125216199, "BETMIGA": 1.1896245130664058, "BIKTARVY": 1.2375912729717713, "BOTULINUM": 1.753180212110128, "BRINTELLIX": 0.5765379599819705, "BRIVARACETAM": 11.773118964915284, "BRIVIACT": 6.431018476859681, "BUDESONIDE": 0.2547559934028358, "BUPIVACAINE": 1.1495298792919106, "BUPRENORPHINE": 5.045477794264775, "CAFFEINE": 47.04701700739756, "CANNABIDIOL": 5.429828504700485, "CELECOXIB": 2.27215470601222, "CELLCEPT": 0.5578502282561749, "CHAMPIX": 0.9653045631889235, "CICLOSPORIN": 0.5694481671310085, "CIMZIA": 0.2515033562031227, "CLOPIDOGREL": 0.5696377423182284, "COAPROVEL": 1.1807200312075976, "COMIRNATY": 0.4613796506852303, "COMTAN": 2.809042268202215, "CYMBALTA": 1.2224725939723509, "CYTARABINE": 0.3567413555116628, "DABRAFENIB": 2.78332873890958, "DARZALEX": 0.9395212830518423, "DASATINIB": 2.285508096492271, "DENOSUMAB": 2.8873848975006706, "DEXAMETHASONE": 0.9368069596067512, "DULOXETINE": 1.0471482351636847, "ELIQUIS": 0.7752551656419974, "ENBREL": 0.1326852364745819, "ENTACAPONE": 5.504113140833774, "ENTRESTO": 0.4226802876730207, "ENZALUTAMIDE": 3.470513562310743, "ESOMEPRAZOLE": 1.4951514659598373, "EVENITY": 0.8627528498719009, "EXELON": 4.520162761715218, "FAMPYRA": 1.5287431406753351, "FENTANYL": 1.5275479331816373, "FORSTEO": 0.4051931882005882, "FORXIGA": 0.4257249711247562, "FYCOMPA": 5.50257768510383, "GARDASIL": 4.309543260610299, "HARVONI": 1.426451894566057, "HIZENTRA": 0.412653332952023, "HUMALOG": 0.6930899281392479, "IBRANCE": 0.4556813283889785, "INCIVO": 0.4191753423059703, "INLYTA": 0.6861263313045134, "INSULIN": 0.4361863195679324, "INTRONA": 2.153039032474172, "JAKAVI": 0.7160275269302019, "JANUMET": 0.274474698131682, "JARDIANCE": 0.1860007558250267, "KALETRA": 0.4436050035576525, "KEPPRA": 4.142314669844695, "KEYTRUDA": 0.6670817148202084, "KYMRIAH": 1.394044021548263, "LACOSAMIDE": 6.854390077970682, "LANTUS": 0.5370520855572163, "LATUDA": 2.251336355519759, "LEMTRADA": 1.07254417846357, "LENVIMA": 0.6780575179858536, "LEVETIRACETAM": 5.90983230436221, "LEVODOPA": 4.37768256367095, "LEVOFLOXACIN": 24.32292928059972, "LYRICA": 1.6084563357338155, "MEKINIST": 0.5862816734708544, "MELATONIN": 2.577869516943856, "MEMANTINE": 3.068364178773824, "MEPOLIZUMAB": 0.2772106199545688, "METFORMIN": 4.855232540577087, "METHOTREXATE": 0.5587261112015919, "MIDAZOLAM": 1.1170784256552386, "NEXAVAR": 0.1897818158504262, "NOVORAPID": 0.78484695132433, "NUCALA": 1.1383678811855231, "OCRELIZUMAB": 0.6081520513167434, "OLANZAPINE": 3.51414960094436, "OPDIVO": 0.587670684109033, "OPTIMARK": 0.2578369948239132, "PANTOPRAZOLE": 1.4253604634029855, "PEGASYS": 0.6915045687229913, "PEGINTRON": 0.8994914560791156, "PEMETREXED": 1.3943019805850607, "PLAVIX": 0.3915809684234488, "PLEGRIDY": 2.043260792377162, "PREGABALIN": 3.0937776508794435, "PROPRANOLOL": 2.553799766936692, "RISPERIDONE": 2.2310978319221086, "SHINGRIX": 0.3980327702380402, "SIFROL": 3.0722213782506933, "SIMPONI": 0.1297555934986709, "SOLIRIS": 0.3305739078664817, "SPIKEVAX": 0.4090094889803371, "SPINRAZA": 0.7009661014215991, "SPIRONOLACTONE": 3.053589141704128, "SPRYCEL": 0.3721934430437773, "STALEVO": 1.59651787524537, "STELARA": 0.1308408627875609, "STIVARGA": 0.324794199375321, "SUBOXONE": 0.6654398954464036, "SUFENTANIL": 1.2535913413564828, "SUTENT": 0.3311433791149484, "TAGRISSO": 0.6949084904982596, "TAMIFLU": 0.3576815807206234, "TASIGNA": 0.4214446903378542, "TELMISARTAN": 3.492785374209239, "TEMOZOLOMIDE": 1.4570028402013604, "TOVIAZ": 3.928432262636733, "TOZINAMERAN": 0.7457659213548339, "VAXZEVRIA": 0.3057464233512124, "VFEND": 0.4242007129387637, "VIAGRA": 0.6801576080887449, "VIMPAT": 4.782300514816201, "VOTRIENT": 0.3685782242780603, "XELJANZ": 0.4103383022104523, "XOLAIR": 0.1326169308347701, "XTANDI": 3.513692213241961, "XYREM": 0.951619054471862, "YESCARTA": 0.9409891987264696, "ZOSTAVAX": 0.5259384968800666, "ZYPADHERA": 3.628932009166916, "ZYPREXA": 1.681537079696266, "null": 1.5264471944375952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2781.json
index 838b01740c3..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2781.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2781.json
@@ -1 +1 @@
-{"null": 3.183863684710422}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2782.json
index 1c42b8d0236..f0f0e7b8b7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2782.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2782.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 3.5965050458968038, "ASPARAGINASE": 18.74000560066149, "AXITINIB": 6.397276805396016, "BRAFTOVI": 2.698300949610533, "BUSULFAN": 6.163553681846095, "CELLCEPT": 2.920065111984814, "CICLOSPORIN": 3.292285880415402, "CIMZIA": 1.285276298675261, "CYTARABINE": 4.314287024392828, "DEXAMETHASONE": 2.536917728165244, "EMTRICITABINE": 4.593915265610619, "ENTYVIO": 1.1526530023264518, "GARDASIL": 6.225442000031031, "HUMAN": 2.34549498838168, "IPILIMUMAB": 10.559856827701788, "JAKAVI": 1.3679704764652012, "KALETRA": 2.452420451529373, "KEPPRA": 1.7390034002366592, "KEYTRUDA": 11.088557889798532, "LACOSAMIDE": 2.815508154519119, "LAMIVUDINE": 3.4205823407608933, "LEVETIRACETAM": 1.7107473342281874, "MEKINIST": 2.754156714888123, "METHOTREXATE": 3.267239466262561, "MMRVAXPRO": 2.413283661116198, "MYCOPHENOLATE": 3.838708246930884, "NIMENRIX": 3.7071687956924055, "OPDIVO": 10.964496760472093, "PEMBROLIZUMAB": 5.745775811421783, "ROACTEMRA": 2.1181556979425618, "SHINGRIX": 3.3898367066919715, "SOLIRIS": 1.044113811490369, "TAMIFLU": 4.245496048573253, "TWINRIX": 6.3053796638871065, "VIMPAT": 2.0739166053675566, "YERVOY": 3.6112130804300513, "ZOSTAVAX": 2.811486779645027}
\ No newline at end of file
+{"ABILIFY": 4.785735173208033, "ARIPIPRAZOLE": 57.69171421807326, "LATUDA": 19.781820449664394, "OLANZAPINE": 34.114997788029484, "ZYPREXA": 17.53869953576088, "null": 2.263082374630977}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2783.json
index 6199557cbb4..235bae8fb9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2783.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2783.json
@@ -1 +1 @@
-{"AVONEX": 80.16806606228965, "BUSULFAN": 6.772221501973049, "GARDASIL": 5.243879314143949, "HUMAN": 11.298858648130482, "IPILIMUMAB": 26.694867674898703, "KEPPRA": 6.880053628296253, "KEYTRUDA": 18.750836167847023, "LEVETIRACETAM": 16.196939528440094, "OLANZAPINE": 2.396197975952264, "OPDIVO": 13.15738855375916, "PEMBROLIZUMAB": 24.493644340755257}
\ No newline at end of file
+{"COMIRNATY": 4.857512809936699, "SPIKEVAX": 1.151427297217706, "null": 0.3604876895503852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2784.json
index 26850ee6925..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2784.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2784.json
@@ -1 +1 @@
-{"ARAVA": 3.7569711732721247}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2785.json
index 1cca8464ca5..45764861ef3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2785.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2785.json
@@ -1 +1 @@
-{"BUDESONIDE": 29.76743538949785, "BUSULFAN": 52.12467669229815, "CELLCEPT": 14.563323764016156, "CICLOSPORIN": 29.119188716507157, "GANCICLOVIR": 342.37811265980645}
\ No newline at end of file
+{"OMALIZUMAB": 120.36878387311698, "null": 1.880737104990534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2786.json
index a17fe0bf834..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2786.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2786.json
@@ -1 +1 @@
-{"CELLCEPT": 12.591439968534626, "CICLOSPORIN": 20.50936311785056, "ERIBULIN": 454.3821086037361, "ROACTEMRA": 10.242279309257995, "ZOSTAVAX": 11.0755512626431}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2787.json
index abd9c33c0b4..57fe87545d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2787.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2787.json
@@ -1 +1 @@
-{"null": 2.158702033383775}
\ No newline at end of file
+{"ABASAGLAR": 1.6704040336824606, "ABILIFY": 0.3819042511304993, "ACTOS": 3.239288111467045, "ACTRAPHANE": 16.90067023250686, "AFINITOR": 0.2320887188743153, "AIMOVIG": 0.4571550577898175, "APIDRA": 6.38891806196238, "AVANDIA": 0.1744215008437726, "BENLYSTA": 0.4296060017631798, "BEXSERO": 3.4456408822460363, "BIKTARVY": 0.6461032316276757, "BRINTELLIX": 0.8385094867649433, "BUDESONIDE": 0.1882399043092041, "BUPIVACAINE": 1.392307107228189, "BUPRENORPHINE": 0.9991657223795856, "BYDUREON": 1.9244331563509331, "BYETTA": 0.5823309117037306, "CHAMPIX": 1.0722853884862635, "CLOPIDOGREL": 1.369290385510166, "COMIRNATY": 1.5248896955821647, "COSENTYX": 0.1286213333951679, "CYMBALTA": 0.8265453781936987, "ELIQUIS": 0.1838613575708578, "ENTRESTO": 0.2586343899935155, "EXFORGE": 0.5163628719283868, "FASENRA": 0.6264174216739993, "FENTANYL": 0.3641576952222835, "FLEBOGAMMA": 2.134677419133161, "FORSTEO": 0.651932112427347, "FORXIGA": 0.8264009287248676, "GARDASIL": 2.122695767082145, "HIZENTRA": 0.6429957731987122, "HUMALOG": 1.3483172731349002, "HYDROCORTISONE": 1.3520648781155875, "IBUPROFEN": 0.4975832907142613, "INSULIN": 2.879720354142908, "IRBESARTAN": 0.7765073551803819, "JANUMET": 0.7561994851924576, "JANUVIA": 0.3035042135121254, "JARDIANCE": 0.3310285081374511, "KEPPRA": 0.1596653492716368, "LANTUS": 3.2402116853828784, "LEVOFLOXACIN": 0.4037514368516795, "LYRICA": 0.3132541755620079, "MENVEO": 1.4355991795766163, "MEPOLIZUMAB": 0.3814896133940018, "MICARDIS": 0.5932977660993423, "MMRVAXPRO": 0.5870669701759695, "MODERNA": 0.5577514362346849, "NAGLAZYME": 1.0440230943290396, "NIMENRIX": 1.4022211524004224, "NOVORAPID": 1.0654430152606265, "OCRELIZUMAB": 2.630172260974184, "OLANZAPINE": 0.162912436854533, "OMALIZUMAB": 0.6463467992177726, "PEGASYS": 0.3937051140994111, "PLAVIX": 0.469242841585652, "PRIVIGEN": 0.7852818235613763, "ROACTEMRA": 0.3525879996064201, "ROTATEQ": 0.6614394595875116, "SAXENDA": 0.6137391363285382, "SHINGRIX": 0.7164343094213312, "SPIKEVAX": 1.6877020086050905, "STELARA": 0.6631285412421136, "SUBOXONE": 1.9882511904363265, "SUTENT": 0.0659701112662361, "TAMIFLU": 0.4833152358058097, "TICAGRELOR": 1.2115514731254986, "TOZINAMERAN": 2.5543404859734338, "TRACLEER": 0.2691383414116902, "TRULICITY": 0.4388156482822246, "TWINRIX": 1.2019710851731569, "VAXZEVRIA": 2.1395006553623674, "VIAGRA": 0.3933489972267598, "VICTOZA": 0.6519954095390796, "XOLAIR": 0.4850471574715237, "ZYPADHERA": 0.9436810332926516, "ZYPREXA": 0.1893966208617529, "null": 0.8727736504556095}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2788.json
index 63e77f41dd0..7426caa2296 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2788.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2788.json
@@ -1 +1 @@
-{"GARDASIL": 25.140718493747272, "null": 1.1773695953319565}
\ No newline at end of file
+{"COMIRNATY": 0.6934353824400019, "null": 0.3157770392370655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2789.json
index 21498e13854..a1c4e4eb8b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2789.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2789.json
@@ -1 +1 @@
-{"null": 1.5410781034375796}
\ No newline at end of file
+{"COMIRNATY": 2.3656814270246915, "METHOTREXATE": 23.90668767758832, "SPIKEVAX": 1.24558617551511, "VAXZEVRIA": 0.7546887008398766, "null": 0.3064003091380227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/279.json
index 91458c757c2..5db20dc5145 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/279.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/279.json
@@ -1 +1 @@
-{"ARAVA": 1.3220616081145198, "CHAMPIX": 10.90144804920299, "PEGASYS": 6.55870769963997, "null": 2.1867888567417912}
\ No newline at end of file
+{"null": 2.846137987720282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2790.json
index ab3cfa58670..7d8a20821e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2790.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2790.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 48.67129686049386, "BUSULFAN": 19.644959725749363, "CELLCEPT": 5.906530671507574, "CICLOSPORIN": 15.433221330210968, "GARDASIL": 2.555811670245405, "SHINGRIX": 4.673784061810857}
\ No newline at end of file
+{"COMIRNATY": 0.6557917105723917, "SPIKEVAX": 1.039091670886987, "TOZINAMERAN": 3.4895024839204045, "VAXZEVRIA": 4.885182367672776, "null": 0.162094727225664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2791.json
index c0811bf87cd..d69d66e3ed8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2791.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2791.json
@@ -1 +1 @@
-{"COMBIVIR": 122.76418322146375, "null": 1.0892007668622985}
\ No newline at end of file
+{"ADALIMUMAB": 0.6535928261365627, "ARAVA": 0.6734440403827483, "ARZERRA": 120.38516549874858, "CICLOSPORIN": 6.029095744491198, "CIMZIA": 3.3408417447739844, "ELIQUIS": 0.9541000373719958, "ENTYVIO": 54.74219325776433, "HUMIRA": 8.95675001293942, "JANUVIA": 9.436159042095078, "RINVOQ": 16.86010954523838, "ROACTEMRA": 4.2673991482481, "SIMPONI": 11.078825352381264, "STELARA": 14.28843861389704, "XELJANZ": 13.198142998667349, "ZOSTAVAX": 1.769897329792104, "null": 0.7685504560203098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2792.json
index 1cf4241c256..cd8a8aa5c7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2792.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2792.json
@@ -1 +1 @@
-{"null": 2.0331920372538743}
\ No newline at end of file
+{"null": 1.119567934549201}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2793.json
index b54043c0493..b67f3e8c352 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2793.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2793.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0162141517452776, "GARDASIL": 11.833981075332511, "VAXZEVRIA": 2.0005163309644427}
\ No newline at end of file
+{"ABRAXANE": 3.2960868771241767, "ADALIMUMAB": 3.715159153588868, "ADCETRIS": 7.604807005373669, "ADCIRCA": 2.3153162566123444, "AFINITOR": 0.8719276478802119, "AIMOVIG": 0.5043988220295668, "ALEMTUZUMAB": 0.6557031184692317, "ALIGN": 52.142493528516816, "ALIMTA": 5.33372639244486, "ALPELISIB": 12.057460787261917, "AMINOSALICYLIC": 27.556620337887317, "ARAVA": 0.2105446730235845, "ARZERRA": 12.539528052800083, "ASPARAGINASE": 1.3850043358911863, "ATAZANAVIR": 0.7149021340761769, "ATEZOLIZUMAB": 7.353632542758248, "ATRIPLA": 0.0557154628161049, "AUBAGIO": 1.004536083717671, "AVAMYS": 13.979288916518088, "AVASTIN": 1.1491843312939924, "AXITINIB": 3.2693490986367117, "AZACITIDINE": 1.3041288424876551, "AZATHIOPRINE": 9.34204412937938, "BAVENCIO": 3.448389427707756, "BENLYSTA": 0.4267833889107923, "BEVACIZUMAB": 0.9100717147551723, "BIKTARVY": 0.5737109701614859, "BINIMETINIB": 15.530351206102909, "BOSULIF": 0.8331970496449751, "BRAFTOVI": 7.346358293903327, "BUDESONIDE": 19.979694483487616, "BUSULFAN": 0.4570848763800175, "BYETTA": 0.8454435664470052, "CABOMETYX": 2.1686606160652278, "CAPECITABINE": 2.004363142838117, "CARMUSTINE": 7.993067130491874, "CELLCEPT": 3.3723189703242804, "CHAMPIX": 0.3600938459781053, "CICLOSPORIN": 1.2870787510064436, "CIMZIA": 0.7595784595575639, "CLOFARABINE": 5.1551841796299085, "CLOPIDOGREL": 0.2357283503082322, "COMIRNATY": 0.1257273211693828, "COSENTYX": 3.491534338896641, "CYMBALTA": 0.1325934508620044, "CYTARABINE": 4.273945618878503, "DABRAFENIB": 2.4084367606706825, "DEXAMETHASONE": 0.8924288435517344, "DOCETAXEL": 1.6003975206619896, "DOXORUBICIN": 1.272684608089865, "ELIQUIS": 0.5804370275860693, "ENBREL": 1.440309130436762, "ENTRESTO": 0.2319486983619928, "ENTYVIO": 6.304240024231298, "ESBRIET": 0.408505851859152, "EXJADE": 0.8961962370087055, "FASENRA": 0.9995401611363424, "FASLODEX": 0.4298641746629636, "FENTANYL": 0.225234582087123, "FIRDAPSE": 1.782116355013122, "FORSTEO": 0.5464361585689991, "GANCICLOVIR": 2.268487688612998, "GARDASIL": 0.2668587155037512, "HERCEPTIN": 0.8270124019160453, "HIZENTRA": 1.092439190608787, "HUMALOG": 0.156839500959845, "HUMIRA": 3.546166370423343, "IBRANCE": 1.0579152251107742, "INFLECTRA": 3.9083336774825295, "INFLIXIMAB": 26.41931226093608, "INLYTA": 2.0752499209956072, "IPILIMUMAB": 66.1042328423263, "IRINOTECAN": 3.787900316862454, "JAKAVI": 0.4352472468000018, "JANUMET": 0.5040811719167664, "JANUVIA": 0.6430308991183495, "JEVTANA": 1.3217348206488138, "KALETRA": 1.040943682882118, "KEYTRUDA": 13.857092327317469, "LANTUS": 0.1976466594128814, "LEMTRADA": 0.5249738633169502, "LENVIMA": 2.12685117337769, "LEVOFLOXACIN": 0.234535313104801, "LIBTAYO": 6.518087400409695, "LYNPARZA": 0.6849721627461102, "MEKINIST": 0.7898438314919162, "MELPHALAN": 2.8259187327942668, "METHOTREXATE": 0.9636140048607114, "MYCOPHENOLATE": 0.8097977403472123, "NEULASTA": 0.6241829330837337, "NEXAVAR": 0.5302189742743618, "NIVOLUMAB": 19.129692055515655, "NUCALA": 0.1956532024040932, "OFEV": 1.3598933323927846, "OLANZAPINE": 0.1429366083768786, "OPDIVO": 37.01876210175181, "OPSUMIT": 0.3817714989306141, "PACLITAXEL": 2.655044352214303, "PEGASYS": 0.6538570379346472, "PEGINTRON": 0.3962275091579949, "PEMBROLIZUMAB": 13.474927436668647, "PIQRAY": 6.025353199249127, "PLAVIX": 0.5005111758035956, "PREGABALIN": 7.960062766123682, "REMICADE": 1.368426945469742, "RINVOQ": 1.942290224578476, "RITUXIMAB": 0.8420781093807014, "ROACTEMRA": 1.887166195454872, "ROTATEQ": 2.589563341612862, "RUBRACA": 0.855815185461254, "SAXENDA": 2.0367498075175074, "SIMPONI": 1.5270343585114698, "SOLIRIS": 0.9965561370017084, "SPIKEVAX": 0.1001620299450555, "SPRYCEL": 5.14594226288751, "STALEVO": 1.6032737956008607, "STELARA": 1.558976315181612, "STIVARGA": 0.3582978733638062, "SUBOXONE": 0.3695623811025835, "SUTENT": 1.1333114736644658, "TAMIFLU": 0.3945777046166355, "TEMSIROLIMUS": 10.273485339860294, "TOBRAMYCIN": 6.109173088166035, "TOZINAMERAN": 0.2367022379451625, "TREMFYA": 0.8756551913729644, "TRODELVY": 7.717976199434435, "TRULICITY": 0.3935383214234277, "VAXZEVRIA": 0.0796536751070165, "VICTOZA": 0.9470584010111002, "VOTRIENT": 0.6676668378829134, "XELJANZ": 1.6268352570398883, "XELODA": 2.2421253890274877, "XOLAIR": 0.4818575037413243, "XTANDI": 0.2390069354860022, "YERVOY": 106.40084007570152, "ZOSTAVAX": 0.3078958770290366, "ZYPREXA": 0.2224604616242233, "null": 0.5172074346601621}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2794.json
index 26fac64bb4b..9c0747fe8c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2794.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2794.json
@@ -1 +1 @@
-{"ABILIFY": 1.939652846393852, "ALLI": 35.93279451767134, "AMIKACIN": 2.0985831552579417, "ASPARAGINASE": 4.697313980582321, "AXICABTAGENE": 20.69605486978968, "BUPIVACAINE": 1.2000059804089815, "BUSILVEX": 7.479959172991069, "BUSULFAN": 1.9522914018964368, "CANCIDAS": 5.113379632810168, "CELLCEPT": 2.835192700007331, "CICLOSPORIN": 3.1162661956165523, "COAPROVEL": 1.52848914829366, "COMBIVIR": 1.4804966422992196, "CUBICIN": 1.769046845591703, "CYTARABINE": 3.1851358349031726, "DACLATASVIR": 9.29907867292176, "DAKLINZA": 4.7604117278802205, "DARZALEX": 2.022518263051156, "DEXAMETHASONE": 2.0056400845430837, "DOXORUBICIN": 1.8656015152048864, "DULOXETINE": 1.1305090006790652, "EFAVIRENZ": 1.78440049237074, "EMEND": 35.7531092545134, "EPCLUSA": 3.036195173689428, "EPIVIR": 1.377653883399768, "EXVIERA": 10.850321978614751, "FAMPRIDINE": 6.542838570896499, "FENTANYL": 1.4953321976710543, "FYCOMPA": 2.860885076501177, "GALVUS": 2.8150101306743283, "GANCICLOVIR": 3.9401389606454673, "HARVONI": 4.8973122787396175, "ICLUSIG": 1.1235117979176832, "INCIVO": 4.113972515939547, "INFANRIX": 2.25666709519876, "INVOKANA": 6.227337894992647, "IPILIMUMAB": 1.1964537341857109, "ISENTRESS": 2.0612704461569376, "KALETRA": 1.4894817877989075, "KEPPRA": 4.723352314775207, "KEYTRUDA": 1.1655514842661154, "KYMRIAH": 6.515280847963993, "KYPROLIS": 1.701756700048971, "LACOSAMIDE": 5.041979811322614, "LAMIVUDINE": 2.128890292933612, "LENVIMA": 3.02890357611472, "LEVETIRACETAM": 3.5538455699192246, "LEVODOPA": 3.995185386549276, "LYRICA": 1.235845581425916, "MABTHERA": 1.5183664779504449, "MEKINIST": 1.1429995672935966, "MELATONIN": 2.2175173387228395, "METHOTREXATE": 1.1666074700291196, "MIDAZOLAM": 4.751640521574726, "MYCOPHENOLATE": 1.166912882773525, "NEORECORMON": 17.58191376622502, "NEXAVAR": 3.0541839438948237, "NOT": 2.511557103640587, "OBINUTUZUMAB": 3.36156516715479, "OCALIVA": 2.0511740424404508, "OLANZAPINE": 1.5108405360050368, "OLYSIO": 3.251525412656104, "OXYBUTYNIN": 3.173506669922768, "PANTOPRAZOLE": 1.6424211005806069, "PEGASYS": 1.455350736958241, "PEGINTERFERON": 1.4042826787499183, "PEGINTRON": 2.280285349255256, "POSACONAZOLE": 11.507125946877672, "PREGABALIN": 2.895270010690523, "REBETOL": 2.1784189194327657, "REGORAFENIB": 9.23306606636068, "RIBAVIRIN": 3.523350458763207, "RISPERIDONE": 4.175079612766444, "SOVALDI": 1.990843367542089, "STIVARGA": 1.9342952615861453, "TACROLIMUS": 3.0534522890184603, "TAMIFLU": 5.498466830890743, "TELMISARTAN": 3.8846470810827474, "THALIDOMIDE": 1.859648398385881, "TISAGENLECLEUCEL": 28.856036376113, "VFEND": 3.658346186714437, "VIGABATRIN": 20.375410411569156, "VIMPAT": 3.95509993170344, "VORICONAZOLE": 3.177670781034009, "YESCARTA": 27.64547330737424, "ZYPREXA": 1.444870064384462, "null": 2.4090440867277128}
\ No newline at end of file
+{"null": 0.569459501492322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2795.json
index df7c55eaf87..e4e94d8dd1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2795.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2795.json
@@ -1 +1 @@
-{"null": 2.0495228807388}
\ No newline at end of file
+{"AIMOVIG": 3.1063170347226383, "ALIMTA": 3.015439272301613, "AVASTIN": 3.4958110430580147, "BEVACIZUMAB": 2.1493355524969098, "BRAFTOVI": 3.2573631848021267, "BYETTA": 3.4904774463724806, "CELLCEPT": 1.0946793750979114, "CICLOSPORIN": 0.7906625941257074, "COMIRNATY": 0.1998324445023269, "CYMBALTA": 1.0791758369903388, "ELIQUIS": 1.2251788712529326, "EVISTA": 8.148677454913416, "FENTANYL": 0.967687219901454, "FORSTEO": 1.362751733756699, "IBUPROFEN": 2.444441148385308, "INTRONA": 16.695882635023157, "JARDIANCE": 0.9123669121157596, "KEYTRUDA": 0.5715953313649197, "MICARDIS": 2.4766731733625207, "NEXAVAR": 2.6145519494873977, "OLANZAPINE": 4.194595910337236, "PEGASYS": 3.7135905529107336, "PEGINTERFERON": 4.380923873031978, "PEGINTRON": 11.214496666626587, "PLAVIX": 2.405003724746148, "RINVOQ": 1.948185106418512, "SOVALDI": 5.542067546483547, "SPIKEVAX": 0.1200474182952768, "SUTENT": 0.3490448988146544, "TAMIFLU": 16.600111831222005, "VAXZEVRIA": 0.2084940404494475, "VICTOZA": 3.451623993523025, "XELJANZ": 0.7450211767543028, "ZYPREXA": 0.6497397574806176, "null": 1.7689801885444236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2796.json
index 2d6c215234a..2b2a6143352 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2796.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2796.json
@@ -1 +1 @@
-{"null": 6.122567086251918}
\ No newline at end of file
+{"AFLIBERCEPT": 116.0068954353034, "ARAVA": 3.3629112183938026, "AUBAGIO": 6.419709516771997, "BUDESONIDE": 7.959958764685112, "CIMZIA": 2.438816257706198, "CLOPIDOGREL": 1.215240627273815, "COAPROVEL": 10.28349103888724, "COMIRNATY": 0.280714746023907, "COMTAN": 15.714081148161643, "COSENTYX": 4.076171958929578, "CYMBALTA": 3.815048637107656, "ELIQUIS": 1.326841850959546, "ENTACAPONE": 39.93642886008693, "IBUPROFEN": 2.4139553955588497, "KEYTRUDA": 3.859844385147076, "OPDIVO": 5.047996020770578, "PEMBROLIZUMAB": 4.974370275844997, "SPIKEVAX": 0.11027318510582, "STALEVO": 29.750259077171357, "TOZINAMERAN": 0.3797499183189931, "VAXZEVRIA": 0.0762191593828281, "null": 1.207168677906547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2797.json
index 9918270808e..63a755acd72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2797.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2797.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 18.0307891808845, "ARANESP": 2.4100481030685983, "ATRIPLA": 34.00985503547428, "AVANDIA": 2.847829702820295, "BUMETANIDE": 33.036327395440416, "CELLCEPT": 1.6580157947443452, "CICLOSPORIN": 4.222335440280807, "HUMALOG": 1.9405611392528508, "LANTUS": 1.0231876777288411, "LEVEMIR": 1.3974702826306116, "NORVIR": 2.6632980671724806, "NPLATE": 2.08161450725286, "OPSUMIT": 1.4566638574381825, "OPTIMARK": 2.0599429233168194, "PANTOPRAZOLE": 3.826238388599465, "RAPAMUNE": 2.7184021550693958, "REVATIO": 1.6981025538671508, "SOLIRIS": 6.830664147567471, "STRIBILD": 13.156522103308722, "TRUVADA": 26.42406254763668, "VELTASSA": 7.336852987913095, "VIREAD": 34.05433917524757}
\ No newline at end of file
+{"RITUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2798.json
index 4f49d319316..2d517a94cfe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2798.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2798.json
@@ -1 +1 @@
-{"FENTANYL": 52.4928000562922, "null": 1.8194526697109343}
\ No newline at end of file
+{"ABATACEPT": 3.727294240779463, "ADALIMUMAB": 7.306519945897834, "AIMOVIG": 0.2725687199327284, "ALIGN": 54.707103603432806, "AMINOSALICYLIC": 41.42627502497341, "ARAVA": 0.1955976207568201, "AUBAGIO": 0.4758375998718414, "AVAMYS": 14.677744942112918, "AZATHIOPRINE": 9.730480944523713, "BRAFTOVI": 1.7300339846801875, "BUDESONIDE": 21.62515829078506, "CABOMETYX": 0.5160352277650891, "CELLCEPT": 0.6456957846583955, "CHAMPIX": 0.4158142301878763, "CICLOSPORIN": 0.783796097374562, "CIMZIA": 1.0166250619307835, "COMIRNATY": 0.2636368274530052, "COSENTYX": 6.0175547758444194, "CYMBALTA": 0.1091175595901341, "ELIQUIS": 0.2303714972093276, "ENBREL": 0.9613509813698026, "ENTYVIO": 71.64935860009636, "ESOMEPRAZOLE": 0.9290372941531664, "EXJADE": 0.3251346530303453, "FENTANYL": 0.1683965963478027, "GANCICLOVIR": 1.5834712441052008, "GARDASIL": 0.5558146548569767, "GOLIMUMAB": 8.373608110345094, "HUMALOG": 0.1373326561783197, "HUMIRA": 11.73562119680784, "HYDROCORTISONE": 1.4910009465769265, "IBRANCE": 0.291268875870223, "IBUPROFEN": 0.8294441159825571, "INFLECTRA": 18.563399184532276, "INFLIXIMAB": 43.56200922035162, "INSULIN": 0.3508842829140928, "IPILIMUMAB": 1.1390490904655457, "JARDIANCE": 0.2516168861930956, "KEPPRA": 0.2749344801114963, "KEYTRUDA": 1.1565050067356122, "LANTUS": 0.0825784423012494, "MEKINIST": 0.3452939012237463, "MEPOLIZUMAB": 0.6386286270221199, "MERCAPTOPURINE": 2.2620051157879253, "METHOTREXATE": 1.7062594739250996, "OCRELIZUMAB": 0.7038448569028009, "OLANZAPINE": 0.1697911985853023, "OPDIVO": 1.131892928898068, "PEGASYS": 0.330937798718933, "PEGINTERFERON": 0.6964364739465173, "PEGINTRON": 0.6810892605391798, "PEMBROLIZUMAB": 0.8748749882276196, "PLAVIX": 0.453270426067261, "PREGABALIN": 8.455248989823694, "REMICADE": 15.222058121390804, "RIBAVIRIN": 0.8116526593389386, "RINVOQ": 6.825088940554495, "ROACTEMRA": 0.3674755602476908, "SAXENDA": 0.4149651089082014, "SHINGRIX": 0.3359849162819342, "SIMPONI": 23.719875874466226, "SOLIRIS": 0.4172976335562218, "SPIKEVAX": 0.1716488105756776, "SPRYCEL": 0.6396163729567816, "STELARA": 16.233250958425717, "SUTENT": 0.1144653273903427, "TOZINAMERAN": 0.4226669719127727, "TREMFYA": 1.0091718166697274, "UPADACITINIB": 6.332032557249201, "VAXZEVRIA": 0.1272929296765649, "VEDOLIZUMAB": 30.062009106782423, "VICTOZA": 0.4991408961718696, "XELJANZ": 11.025945558038677, "XOLAIR": 0.3908751388296182, "YERVOY": 4.756232395930666, "ZOSTAVAX": 0.226308430173979, "null": 0.5423139446412225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2799.json
index 70a3f94a9c3..048e663c4e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2799.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2799.json
@@ -1 +1 @@
-{"FENTANYL": 225.31315390040407}
\ No newline at end of file
+{"COMIRNATY": 1.2484298090118, "SPIKEVAX": 0.3699754533560396, "null": 1.3838734626564235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/28.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/28.json
index d8c1bc3c155..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/28.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/28.json
@@ -1 +1 @@
-{"ELIQUIS": 6.592813849834514, "ENOXAPARIN": 72.10543517281607, "null": 1.46622887337078}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/280.json
index fcafd65905f..e94b6056b08 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/280.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/280.json
@@ -1 +1 @@
-{"OLANZAPINE": 15.003346999506974, "SUBOXONE": 13.518564500714602, "ZYPREXA": 8.77376466562783, "null": 1.7665589682042355}
\ No newline at end of file
+{"DOXORUBICIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2800.json
index 9d3174908b8..52e90714c4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2800.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2800.json
@@ -1 +1 @@
-{"OPSUMIT": 55.20156363860814, "TRACLEER": 70.75848955340513}
\ No newline at end of file
+{"null": 0.4920994718959467}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2801.json
index e26c1b633b8..5c1122093b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2801.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2801.json
@@ -1 +1 @@
-{"null": 3.018316396517281}
\ No newline at end of file
+{"KALETRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2802.json
index a354648b944..4aaa098c249 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2802.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2802.json
@@ -1 +1 @@
-{"OPTIMARK": 198.569371909976}
\ No newline at end of file
+{"null": 1.1886398168110262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2803.json
index 946bf8182f2..d8bfbf1b6d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2803.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2803.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 7.656599213260483, "CELLCEPT": 5.708008270847819, "CICLOSPORIN": 2.934373725394736, "CUBICIN": 54.16991503955047, "DAPTOMYCIN": 66.15875443104805, "DEXAMETHASONE": 1.7336795279773871, "ELIQUIS": 1.4042827986738513, "FENTANYL": 1.7231387499596371, "FORXIGA": 3.2046747205024726, "JARDIANCE": 1.1819857691074642, "KEYTRUDA": 1.4641428530343346, "METHOTREXATE": 2.2081796098312885, "OPSUMIT": 1.382804536993347, "PEGASYS": 3.8035423732818976, "PEGINTRON": 1.2207846623530478, "RITUXIMAB": 2.1507371414184453, "ROACTEMRA": 7.115966452420175, "SIMPONI": 2.315555676713017, "SOLIRIS": 5.17153649138042, "STELARA": 1.9483404120546663, "SUBOXONE": 7.490375344788055, "TRACLEER": 2.3131091085449773, "null": 1.1852236107564669}
\ No newline at end of file
+{"null": 2.14076618919358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2804.json
index 3bf9e45403b..436c07edc00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2804.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2804.json
@@ -1 +1 @@
-{"PEGASYS": 3.966557141860426}
\ No newline at end of file
+{"ARANESP": 1.070877508545953, "ARAVA": 0.0776951589844707, "AVASTIN": 4.270630284671753, "BEVACIZUMAB": 3.239982327854637, "BYDUREON": 2.2981912976371226, "BYETTA": 2.788786470719369, "CELLCEPT": 2.532822812065124, "CICLOSPORIN": 1.098398810478121, "CIMZIA": 0.7946514678007082, "CLOPIDOGREL": 0.8450238900798632, "COMIRNATY": 0.0562657561132327, "COSENTYX": 1.5736788763945293, "ELIQUIS": 4.28996394105052, "ENBREL": 0.5834393564348016, "ENTYVIO": 3.036357706458535, "EVENITY": 3.350564067893551, "EXFORGE": 1.457168285703947, "FORSTEO": 2.532868328252632, "FORXIGA": 1.0853768214725934, "HUMALOG": 2.863050597621588, "HUMIRA": 2.2499781799661105, "IBRANCE": 0.4737549061908212, "INCRUSE": 3.6854887227287287, "INSULIN": 0.8305687261011289, "IRINOTECAN": 2.7028108512053883, "JAKAVI": 1.2363854893485522, "JANUMET": 1.371551743582382, "JANUVIA": 2.961843118982559, "JARDIANCE": 1.5626251210471611, "KEYTRUDA": 0.448398180367685, "LANTUS": 2.6897770000763117, "LEVEMIR": 1.4782799129802433, "LIXIANA": 3.930055850722903, "LONSURF": 7.129126715469529, "LYRICA": 1.0848679279535547, "MEKINIST": 2.185977507513396, "MICARDIS": 4.389184739190488, "NEXAVAR": 0.4272686219310753, "NPLATE": 2.439802816128359, "OPSUMIT": 1.368552016870493, "PEGASYS": 0.2369321283531739, "PLAVIX": 0.8879753719376212, "REMICADE": 5.5959722442554165, "RINVOQ": 2.7669168560099977, "ROACTEMRA": 1.7751106679247697, "SIMPONI": 3.346514946640281, "SPIKEVAX": 0.036072332554589, "SPRYCEL": 1.2917900426220132, "STELARA": 4.531660647555649, "STIVARGA": 63.01735440490184, "TAGRISSO": 1.9461490398863055, "TASIGNA": 1.0744644701249044, "TRACLEER": 1.654461040000627, "TRELEGY": 2.0932265359268567, "TREMFYA": 2.487419958831538, "TRULICITY": 1.6442304465718247, "VECTIBIX": 76.09850701164986, "VIAGRA": 3.565595403451879, "VICTOZA": 2.6001533765456406, "XELJANZ": 2.640231325599843, "XOLAIR": 2.895647900133583, "XTANDI": 1.287646852549858, "ZOSTAVAX": 1.3324558415620311, "ZYPREXA": 0.3839853644194914, "null": 1.5076014331415508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2805.json
index 9bf2ef8bb64..66971823086 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2805.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2805.json
@@ -1 +1 @@
-{"ELIQUIS": 21.841272133949232}
\ No newline at end of file
+{"AVASTIN": 45.47408539876791, "BEVACIZUMAB": 49.09505698256709, "CAPECITABINE": 18.075484032921047, "IRINOTECAN": 33.91054722486251, "LONSURF": 27.655400712636325, "STIVARGA": 91.76225954538565, "null": 0.5834432914241553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2806.json
index 63d9d9fede0..b587636b1fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2806.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2806.json
@@ -1 +1 @@
-{"CUBICIN": 303.4296897289892, "null": 1.6073534768700652}
\ No newline at end of file
+{"STIVARGA": 131.97498990633417, "null": 0.2799038284879683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2807.json
index 499aee559aa..e4079eb49c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2807.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2807.json
@@ -1 +1 @@
-{"IPILIMUMAB": 34.18757059239579, "KEYTRUDA": 9.525666289731902, "OPDIVO": 19.05909630543023, "YERVOY": 46.589106690286464, "null": 1.2235218613598806}
\ No newline at end of file
+{"null": 0.6328555915525093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2808.json
index f549bbb127f..1dd02dca6e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2808.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2808.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 34.06964272326116, "ARAVA": 6.369846722976291, "COMIRNATY": 1.055535730577029, "LEMTRADA": 63.33927446755166, "TOZINAMERAN": 2.5371080243434303}
\ No newline at end of file
+{"null": 2.223040555722444}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2809.json
index b7d80b1f091..b0f4c569e19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2809.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2809.json
@@ -1 +1 @@
-{"ANAKINRA": 56.488394481051664, "ARAVA": 1.4231181594018996, "IBRANCE": 5.627225351599845, "PEGASYS": 3.844208586611816, "SIMPONI": 9.265416104906818, "null": 1.2279512698830586}
\ No newline at end of file
+{"null": 0.5512368642797312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/281.json
index 80626b5cf87..246ec4f1d35 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/281.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/281.json
@@ -1 +1 @@
-{"null": 1.2834699380452856}
\ No newline at end of file
+{"null": 0.9500807176259892}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2810.json
index 3ebd25d44c6..db9fc391e70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2810.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2810.json
@@ -1 +1 @@
-{"COMIRNATY": 1.964871659258465}
\ No newline at end of file
+{"null": 0.998193471464212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2811.json
index 7fc23f0de06..96f90445cbb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2811.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2811.json
@@ -1 +1 @@
-{"ESMYA": 131.67294194371905, "EVISTA": 604.4527609197656}
\ No newline at end of file
+{"XELJANZ": 14.84940146683996, "null": 1.9498534471743576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2812.json
index b307c3db30d..f02cf5c01fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2812.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2812.json
@@ -1 +1 @@
-{"null": 1.3737295251571595}
\ No newline at end of file
+{"ELIQUIS": 4.711981085880072, "null": 0.7337061058151443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2813.json
index 01d56edc801..fe3ee9f3796 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2813.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2813.json
@@ -1 +1 @@
-{"ESMYA": 60.53331518222216, "EVISTA": 231.7981583463173, "LANTUS": 1.359816356923584, "STELARA": 5.815611036089845, "TESTOSTERONE": 45.82588833505356, "TREMFYA": 25.99874083376843, "XELJANZ": 2.7481922947055986, "null": 1.5410799557040584}
\ No newline at end of file
+{"null": 1.0711855212347356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2814.json
index 5107f31dd4a..265a732aa31 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2814.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2814.json
@@ -1 +1 @@
-{"null": 1.3001172058324495}
\ No newline at end of file
+{"ENTYVIO": 25.90566922264777, "null": 0.5589725786929561}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2815.json
index f6b9fde876d..8669278819f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2815.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2815.json
@@ -1 +1 @@
-{"null": 1.1927577248925028}
\ No newline at end of file
+{"SPIRONOLACTONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2816.json
index bff12a0646a..08954726bfe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2816.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2816.json
@@ -1 +1 @@
-{"null": 3.5785656896673106}
\ No newline at end of file
+{"SUTENT": 7.961280334690032, "null": 0.6962925853119403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2817.json
index 283a01aa40e..9b4d9d48aa5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2817.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2817.json
@@ -1 +1 @@
-{"ESMYA": 449.8768029927492, "EVISTA": 133.67793517664762, "null": 2.300546978580927}
\ No newline at end of file
+{"CLOPIDOGREL": 45.71872649689318, "null": 2.468161136512688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2818.json
index 7c0916cc444..b6ced5bcf34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2818.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2818.json
@@ -1 +1 @@
-{"null": 1.4605737060642596}
\ No newline at end of file
+{"INCRUSE": 68.13562467156547, "JANUVIA": 10.525422215393371, "ZOSTAVAX": 35.99514407040134, "null": 1.3619390312012578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2819.json
index 440865c15f3..e067671d6be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2819.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2819.json
@@ -1 +1 @@
-{"VOTRIENT": 134.39772500777065}
\ No newline at end of file
+{"null": 3.504524013026683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/282.json
index 48d13ce8bee..334d739276e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/282.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/282.json
@@ -1 +1 @@
-{"null": 1.486439739549122}
\ No newline at end of file
+{"null": 1.0482035107283596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2820.json
index 124728c79c0..5340dfa6dcb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2820.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2820.json
@@ -1 +1 @@
-{"ESMYA": 694.6384135973799, "null": 2.144268970885839}
\ No newline at end of file
+{"null": 6.564447189644231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2821.json
index 6107906d2dd..df8f05ce62e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2821.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2821.json
@@ -1 +1 @@
-{"AIMOVIG": 1.5899506725501138, "AMINOSALICYLIC": 3.562227234659592, "BOTULINUM": 13.42008441955809, "CIMZIA": 1.683401942934882, "COMIRNATY": 3.13651424548092, "COSENTYX": 2.5539051015581298, "FENTANYL": 2.128864621206541, "GARDASIL": 7.821178586733486, "LYRICA": 3.907113484818408, "STELARA": 2.597790926746449, "TOZINAMERAN": 2.4706290351643827}
\ No newline at end of file
+{"null": 0.3241822445777051}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2822.json
index 747c2b80d7b..e99d8453e16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2822.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2822.json
@@ -1 +1 @@
-{"IBUPROFEN": 36.862718427194565, "STELARA": 9.334452148806136, "null": 2.792561727127509}
\ No newline at end of file
+{"BYETTA": 20.822940479109377, "CHLORMETHINE": 711.9590742088476, "JANUMET": 10.511371507212884, "JANUVIA": 6.694468535768031, "STELARA": 3.549986254353587, "ZOSTAVAX": 11.035758519173053, "null": 1.7137323603507602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2823.json
index 5ea70ec4647..f4a4454eb11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2823.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2823.json
@@ -1 +1 @@
-{"AFLIBERCEPT": 72.65942524143358, "AVASTIN": 4.775386871321967, "BEOVU": 64.95328821927362, "BROLUCIZUMAB": 48.52307633803014, "DEXAMETHASONE": 6.643884540522487, "EYLEA": 1942.745293787745, "LEVOFLOXACIN": 3.4991728629313754, "MVASI": 48.67939417933724, "MYCOPHENOLATE": 8.316813263237535, "NEVANAC": 66.42183283252882, "VORICONAZOLE": 3.649767260934433}
\ No newline at end of file
+{"AVASTIN": 0.9439267541406532, "BEVACIZUMAB": 1.5408157566103189, "ELIQUIS": 0.0818914822122182, "LANTUS": 0.1181578982219614, "STIVARGA": 20.789843672744063, "VALSARTAN": 2.0160414758573206, "null": 38.21481210212264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2824.json
index 9048b08cb3d..0ba0f4ecf93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2824.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2824.json
@@ -1 +1 @@
-{"ZOSTAVAX": 18.06499122502921, "null": 1.6625699564856682}
\ No newline at end of file
+{"AFLIBERCEPT": 255.97948715640288, "AVASTIN": 35.76908767513393, "BEVACIZUMAB": 122.2064742113318, "CAPECITABINE": 15.91871595095995, "IRINOTECAN": 84.31223414303267, "LONSURF": 31.77209285306245, "PANITUMUMAB": 179.06056635253694, "REGORAFENIB": 397.3651147397352, "STIVARGA": 409.7156699371501, "VECTIBIX": 188.6553068742261, "null": 0.1097857872296805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2825.json
index bcedbc0614f..c22a007c094 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2825.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2825.json
@@ -1 +1 @@
-{"null": 1.1329568019540135}
\ No newline at end of file
+{"STIVARGA": 325.45601586150894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2826.json
index fd92bbc9eda..037c700e724 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2826.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2826.json
@@ -1 +1 @@
-{"COMIRNATY": 2.554716458727643}
\ No newline at end of file
+{"null": 5.987937106416911}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2827.json
index cfd3351586f..c1492f675a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2827.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2827.json
@@ -1 +1 @@
-{"null": 4.147715741662421}
\ No newline at end of file
+{"null": 8.707481839845515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2828.json
index 21fbd808c84..e8ab0c78b96 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2828.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2828.json
@@ -1 +1 @@
-{"ABILIFY": 1.875089558361598, "BIKTARVY": 16.436345289081938, "BRIDION": 45.79241209800414, "CELLCEPT": 2.055885020516996, "CICLOSPORIN": 2.610026620402992, "EXJADE": 2.641980853039686, "FENTANYL": 1.6019426235988958, "GARDASIL": 1.4323129266231265, "HARVONI": 3.7339567196810086, "ISENTRESS": 10.435015647090175, "JARDIANCE": 2.088495870063936, "KALETRA": 15.18056442012873, "KEPPRA": 1.2310906359820906, "KEYTRUDA": 1.1855772518291088, "MIDAZOLAM": 5.455276681256489, "NUCALA": 2.146490429448382, "OLANZAPINE": 3.365308209875552, "OPSUMIT": 4.859550526111471, "REMDESIVIR": 20.5522805833344, "SIMPONI": 1.152335464427139, "TRACLEER": 10.505880620412116, "TRELEGY": 3.0459803455103094, "XOLAIR": 1.3169948903704374, "ZYPREXA": 3.821457620439124, "null": 1.682789315794819}
\ No newline at end of file
+{"null": 4.480327940476667}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2829.json
index 142920c790e..6720d08ad54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2829.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2829.json
@@ -1 +1 @@
-{"BRIDION": 122.43583855633123, "NAGLAZYME": 85.13119231268217, "null": 2.940836801598202}
\ No newline at end of file
+{"STIVARGA": 94.30195652008835, "null": 2.448134644118145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/283.json
index c57232a4ba2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/283.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/283.json
@@ -1 +1 @@
-{"null": 1.0073536249268118}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2830.json
index 1414e872733..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2830.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2830.json
@@ -1 +1 @@
-{"ROTATEQ": 3157.629152286781}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2831.json
index 23ae486f3fd..32bc6c994fd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2831.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2831.json
@@ -1 +1 @@
-{"BRINTELLIX": 4.85772159000177, "BUPRENORPHINE": 6.498482766159041, "LATUDA": 13.99529255170698, "PEGASYS": 1.7772556098638763, "SUBOXONE": 8.18318350101582, "SUTENT": 1.2100504676609565, "TOZINAMERAN": 1.035869456324272, "XELJANZ": 3.321596396481136, "null": 1.6361587539423266}
\ No newline at end of file
+{"CIMZIA": 7.05936456594162, "STELARA": 4.43726404744408, "XELJANZ": 4.496279627353837, "null": 1.1491327868426862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2832.json
index 5c4806dc1d6..f400abc9c49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2832.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2832.json
@@ -1 +1 @@
-{"BUSULFAN": 108.7220419288741, "CICLOSPORIN": 46.17408515418877}
\ No newline at end of file
+{"AIMOVIG": 9.897092476525824, "COMIRNATY": 0.1839704038682521, "LANTUS": 2.510365313843642, "VAXZEVRIA": 0.1907046048041173, "VFEND": 88.04781897278984, "VIAGRA": 13.773448885603768, "null": 0.9046890856314208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2833.json
index 576c95729d3..5f6414f40c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2833.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2833.json
@@ -1 +1 @@
-{"BUSILVEX": 413.5642157944732, "BUSULFAN": 186.87934963169707, "CICLOSPORIN": 22.777587450676133, "CYTARABINE": 16.921972193368926, "DEXAMETHASONE": 54.12105346112561}
\ No newline at end of file
+{"null": 2.07180226505524}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2834.json
index 09168062646..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2834.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2834.json
@@ -1 +1 @@
-{"COMIRNATY": 5.826477930954527}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2835.json
index d656ce18cea..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2835.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2835.json
@@ -1 +1 @@
-{"EMTRICITABINE": 294.15624518269175, "null": 1.9921292396525248}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2836.json
index 05945a0386f..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2836.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2836.json
@@ -1 +1 @@
-{"TOZINAMERAN": 3.5363422881975803, "XOLAIR": 6.504797389452493, "null": 1.7982877736902798}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2837.json
index 69cfd2225ff..cd5b1e83b52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2837.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2837.json
@@ -1 +1 @@
-{"null": 1.974569651104621}
\ No newline at end of file
+{"ABASAGLAR": 0.8753750035385924, "ABILIFY": 2.0717396904327865, "ACIDOPHYLUS": 189.14256591198043, "ACTOS": 1.513857542112624, "ACTRAPID": 2.5153928242969834, "ADALIMUMAB": 0.2447258991745821, "ADENURIC": 1.591867411969588, "AERIUS": 0.8922260870827231, "AFINITOR": 0.1905310484464579, "AIMOVIG": 0.1533204102062451, "ALL": 2.2575438490669297, "AMIKACIN": 0.5719113695556273, "APIDRA": 0.866512857710242, "APROVEL": 2.5074433303439903, "ARANESP": 0.13026824266141, "ARAVA": 0.0479900203142084, "ARIPIPRAZOLE": 0.9747211972993536, "ARIXTRA": 2.305248203011274, "ASPARAGINASE": 0.536647227679388, "ATRIPLA": 0.039697381950365, "AUBAGIO": 0.1504442320010653, "AVANDIA": 0.6226814723078564, "AVASTIN": 0.5888968795995461, "AZATHIOPRINE": 0.3730313874203971, "AZTREONAM": 3.954640347295145, "BENLYSTA": 0.2273788409690631, "BENZODIAZEPINE": 10.88343757801302, "BEVACIZUMAB": 1.1514778053015668, "BIKTARVY": 0.4196003426515341, "BRILIQUE": 1.954133210499632, "BRINTELLIX": 0.7557957506347219, "BRIVIACT": 1.1069710572582512, "BUDESONIDE": 0.2470950349838293, "BUPIVACAINE": 1.3079590595273094, "BUPRENORPHINE": 3.017480500664402, "BUSULFAN": 0.238256377931332, "BYETTA": 0.2760500896308473, "CAPECITABINE": 0.5727563074201496, "CASPOFUNGIN": 1.7786820443268128, "CELECOXIB": 0.6935955812450394, "CELLCEPT": 3.470860190543678, "CHAMPIX": 0.4102238485162392, "CICLOSPORIN": 0.4403856036822956, "CIMZIA": 0.0562947681989684, "CLOPIDOGREL": 0.9560535004440044, "COAPROVEL": 1.051557929834199, "COMBIVIR": 0.4074235831345292, "COMIRNATY": 0.0637352327723327, "COMTAN": 3.6829835114493887, "COSENTYX": 0.0853857078921522, "CYMBALTA": 1.6019574214511891, "CYTARABINE": 0.1506830808577864, "DESLORATADINE": 1.9679245420246367, "DEXAMETHASONE": 1.001928348743941, "DOCETAXEL": 0.2557182631607325, "DOXORUBICIN": 0.7509744123599558, "DULOXETINE": 7.235220120236009, "EBIXA": 2.5440764636835174, "ELIQUIS": 0.9922550521243664, "EMEND": 1.1769162080793465, "ENTRESTO": 0.1368884116013242, "ENTYVIO": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2838.json
index b3134c9fe97..83e0778fe4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2838.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2838.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 9.87963793545645, "ALIMTA": 6.178735748091023, "ASPARAGINASE": 37.05199396358634, "AVASTIN": 4.352757073786924, "BENLYSTA": 2.0019553084667354, "BEVACIZUMAB": 4.482447271367416, "CAPECITABINE": 11.84032310285785, "CARMUSTINE": 33.228963411339805, "CELLCEPT": 2.672440989504256, "CICLOSPORIN": 1.474944791373777, "COSENTYX": 3.3092100893222827, "CYTARABINE": 4.548323001829614, "DOCETAXEL": 8.507164252657601, "ENTYVIO": 6.37977261619378, "FASLODEX": 1.835941167682694, "FILGRASTIM": 11.024011570548574, "HUMIRA": 1.592781807466762, "IPILIMUMAB": 12.609878247950771, "IRINOTECAN": 9.125975784089093, "JEVTANA": 6.867742130091692, "KEYTRUDA": 4.845658164072351, "OPDIVO": 6.857863249905643, "ROTATEQ": 17.220739490262165, "SOMATROPIN": 18.699391002719537, "STELARA": 1.418550646284196, "TRODELVY": 8.783494134932793, "XELJANZ": 1.005647054141242, "XELODA": 13.7171912538231, "YERVOY": 6.830994180042691, "null": 1.020962171727233}
\ No newline at end of file
+{"JARDIANCE": 39.39240408212186, "null": 1.3534383220088049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2839.json
index 6be56fb8959..9c21761c4fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2839.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2839.json
@@ -1 +1 @@
-{"BRAFTOVI": 20.562960322257915, "CELLCEPT": 6.924872655561069, "CIMZIA": 3.17329169488174, "ENTYVIO": 9.829030077610696, "IBRANCE": 4.492728947663778, "KEYTRUDA": 3.897667219372453, "PEGINTRON": 8.562411264644265, "XELJANZ": 7.408909309555337, "null": 1.031755652060855}
\ No newline at end of file
+{"null": 0.5610331033905649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/284.json
index e1956297bfe..c51de39fdfd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/284.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/284.json
@@ -1 +1 @@
-{"ABILIFY": 7.529271427556875, "BUDESONIDE": 4.011405458055314, "CHAMPIX": 6.64324411259996, "CYMBALTA": 2.8587493073867547, "MELATONIN": 33.60555518721919, "PEGASYS": 2.148644745952752, "PEGINTRON": 10.367670195178016, "SUBOXONE": 13.524850524290496, "ZYPREXA": 6.73902509706444, "null": 1.650731178249328}
\ No newline at end of file
+{"COMIRNATY": 1.942764020189835, "FORSTEO": 39.98048944320949, "SIMPONI": 12.777262155198896, "SPIKEVAX": 0.3889426639865946, "VAXZEVRIA": 1.0374765830703463, "null": 0.5771445171215184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2840.json
index 0e5c6887b24..2eddeaa0399 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2840.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2840.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 131.083245861796}
\ No newline at end of file
+{"ASPARAGINASE": 16.583530976311824, "NEXAVAR": 24.850311588862976, "PEGASYS": 2.1299743612146083, "STIVARGA": 9.135235659397043, "SUTENT": 2.4195931960653936, "null": 1.9212890000615164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2841.json
index 141b208a50b..c23dfc88d1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2841.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2841.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 17.30393805754053, "ASPARAGINASE": 278.03534902497915, "CICLOSPORIN": 5.4239941403072605, "CYTARABINE": 61.83884298708227, "OCEAN": 1176.461061785761, "REMICADE": 37.7251054598289}
\ No newline at end of file
+{"null": 1.122026655990208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2842.json
index 74ee9467e02..08ba635f5ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2842.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2842.json
@@ -1 +1 @@
-{"BUSULFAN": 92.0940402289468}
\ No newline at end of file
+{"ARIPIPRAZOLE": 4.671886070662103, "BEVACIZUMAB": 9.994774013281198, "BUPRENORPHINE": 4.118413118420067, "CENOBAMATE": 449.80007570716, "CICLOSPORIN": 0.8689215374274251, "CLOPIDOGREL": 2.907030737302004, "COMIRNATY": 0.1455489007719468, "DEXAMETHASONE": 3.1092100583490416, "DULOXETINE": 5.014344274806026, "ELIQUIS": 0.7046004113072826, "ESOMEPRAZOLE": 6.425224079691463, "FENTANYL": 3.972992779800187, "GLUCAGON": 108.83144302429626, "IBUPROFEN": 6.542061949641314, "MIDAZOLAM": 6.312113461185393, "OLANZAPINE": 8.0668834968724, "PREGABALIN": 19.351675561862734, "PROPRANOLOL": 19.611845637474183, "VAXZEVRIA": 0.2146365066451049, "null": 2.907442793231717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2843.json
index 9b8cdd727f4..07ef3aade99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2843.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2843.json
@@ -1 +1 @@
-{"null": 1.1050395043329635}
\ No newline at end of file
+{"ROTATEQ": 291.2914584332081, "null": 0.5773065971612161}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2844.json
index 3238c988643..58c77c64b41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2844.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2844.json
@@ -1 +1 @@
-{"null": 1.6878817313017702}
\ No newline at end of file
+{"FORSTEO": 36.5878024675228, "null": 0.4136554611300718}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2845.json
index 47a17cd2322..8f82b45c4f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2845.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2845.json
@@ -1 +1 @@
-{"null": 1.3959986505165196}
\ No newline at end of file
+{"ABILIFY": 2.0619553193761564, "AIMOVIG": 9.291579852347326, "BUPRENORPHINE": 3.1939418594662747, "COMIRNATY": 0.2721625056277339, "CYMBALTA": 1.2223242284573228, "FENTANYL": 2.680790799586004, "KEPPRA": 3.389334430449012, "LANTUS": 1.1610328203975993, "OLANZAPINE": 4.927727182829932, "PEGASYS": 0.8275888506883657, "SPIKEVAX": 0.3425586163281107, "TOZINAMERAN": 0.5583268515529041, "VAXZEVRIA": 0.1266239895751783, "ZYPREXA": 2.3856103067994647, "null": 2.675409826379885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2846.json
index 35f896c85f4..023e58d1bf2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2846.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2846.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 45.70661841003324, "BUSULFAN": 60.51529564307113, "CICLOSPORIN": 5.221644009467364, "CUBICIN": 195.76423322614875}
\ No newline at end of file
+{"BUPRENORPHINE": 4.800253182177161, "CLOPIDOGREL": 2.1103262895793646, "COMIRNATY": 0.0830047403097251, "ELIQUIS": 3.5661844682726334, "ENOXAPARIN": 11.11984276046891, "FENTANYL": 7.295052227479652, "GLUCAGON": 194.11095942823283, "LEVOFLOXACIN": 2.7841164960330573, "OLANZAPINE": 4.712541083242736, "PLAVIX": 2.3398963632604493, "VAXZEVRIA": 0.0996043034854471, "null": 2.3729294991815832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2847.json
index 8136175857a..c865484fa95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2847.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2847.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 13.504357997265055, "AMIKACIN": 79.11836155207891, "ASPARAGINASE": 19.15116955114026, "BASILIXIMAB": 56.48677532816336, "BORTEZOMIB": 34.52327111328297, "BUSULFAN": 23.388969039942488, "CASPOFUNGIN": 41.98246259459722, "CELLCEPT": 3.401247265810036, "CICLOSPORIN": 11.269417135707396, "CLADRIBINE": 53.53836207405568, "CUBICIN": 45.219181603164905, "CYTARABINE": 8.532661766741862, "DEXAMETHASONE": 5.63388162505178, "GANCICLOVIR": 15.854964432961388, "KYMRIAH": 13.595702756095022, "MYCOPHENOLATE": 18.384731467801107, "RITUXIMAB": 3.663295371341497, "SOLIRIS": 6.992351349020736}
\ No newline at end of file
+{"null": 2.415539241758726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2848.json
index 49961aff153..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2848.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2848.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 28.706973867330056, "CICLOSPORIN": 11.18912388056708, "SOLIRIS": 20.70417650545461}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2849.json
index 7eebb30240c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2849.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2849.json
@@ -1 +1 @@
-{"CYTARABINE": 50.97053886214012}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/285.json
index 88ed882b3b0..dcd65992b53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/285.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/285.json
@@ -1 +1 @@
-{"null": 3.448287030836279}
\ No newline at end of file
+{"COMIRNATY": 1.9209782979674663}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2850.json
index 2ae4c72f603..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2850.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2850.json
@@ -1 +1 @@
-{"ABRAXANE": 11.859604200114305, "ADCETRIS": 23.40533475392848, "ALIMTA": 6.342254726887617, "AMINOSALICYLIC": 3.209273320618893, "AVASTIN": 5.799014917436428, "BEVACIZUMAB": 2.446079362534105, "BRAFTOVI": 9.463731640467063, "BUSULFAN": 2.444250509017356, "CABOMETYX": 2.977205897804604, "CANCIDAS": 7.639021283501832, "CAPECITABINE": 5.486842003799529, "CASPOFUNGIN": 11.729271279627609, "CELLCEPT": 4.900493811886931, "CYTARABINE": 1.5446285096819488, "DEXAMETHASONE": 3.920765325097416, "DOCETAXEL": 5.291246879271678, "HALAVEN": 8.024529103344896, "INLYTA": 2.7525149917432192, "IPILIMUMAB": 14.18662319144116, "IRESSA": 5.2064274348912765, "JAKAVI": 1.8769755026996309, "JEVTANA": 8.001727037253637, "KEYTRUDA": 16.608466108090273, "LEVETIRACETAM": 1.785483827794487, "LEVOFLOXACIN": 1.7032008963156269, "NEXAVAR": 2.2230404333965, "OPDIVO": 30.508664701013632, "PEMBROLIZUMAB": 3.135613259331224, "ROTATEQ": 3.9780205953263583, "SPRYCEL": 4.007591691421756, "STIVARGA": 1.711226436978255, "TRASTUZUMAB": 65.77153017306227, "XELODA": 15.604784290694685, "YERVOY": 80.62849752865445, "null": 1.1101371294442273}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2851.json
index f5c3b8cef7e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2851.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2851.json
@@ -1 +1 @@
-{"null": 1.0751797158828131}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2852.json
index 4e3180bad21..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2852.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2852.json
@@ -1 +1 @@
-{"KEYTRUDA": 2.117151703327928, "NEXAVAR": 2.0096649774626254, "OSELTAMIVIR": 68.26254035280253, "PEGINTRON": 2.1140361391768483, "PLAVIX": 2.533554145891677, "SPRYCEL": 17.94287258450815, "TAMIFLU": 85.3151506856073, "YERVOY": 37.19148447662393, "null": 2.188235192217729}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2853.json
index e50f4f0ac6e..92afca07999 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2853.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2853.json
@@ -1 +1 @@
-{"CYTARABINE": 46.37593003976208}
\ No newline at end of file
+{"ROACTEMRA": 51.200933697761, "SOLIRIS": 116.1064159145342, "null": 0.4711969509662065}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2854.json
index 8907f61fa40..f74386f6b75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2854.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2854.json
@@ -1 +1 @@
-{"AVASTIN": 67.85565016741296, "ENTYVIO": 26.70261704398224, "STELARA": 16.335500742435432}
\ No newline at end of file
+{"null": 1.3419956826253077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2855.json
index 394f133333f..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2855.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2855.json
@@ -1 +1 @@
-{"STELARA": 31.851220588339142}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2856.json
index 5843d2e71f3..fae2735c42f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2856.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2856.json
@@ -1 +1 @@
-{"null": 1.4331825507332387}
\ No newline at end of file
+{"ROACTEMRA": 68.87987827367803, "SOLIRIS": 40.65927226254822, "null": 0.6587010770049713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2857.json
index e4dcb92b2c8..29d5ab832d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2857.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2857.json
@@ -1 +1 @@
-{"CYTARABINE": 116.68565047832332, "SPINRAZA": 171.5457392307427, "SYNAGIS": 64.6643884308422}
\ No newline at end of file
+{"SOLIRIS": 398.8518921237636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2858.json
index 87140a873b1..3bbae1be1a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2858.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2858.json
@@ -1 +1 @@
-{"ABATACEPT": 18.75733777735539, "ADALIMUMAB": 24.6243911596362, "APREMILAST": 96.69622785994478, "AZATHIOPRINE": 14.581936040276007, "CELECOXIB": 19.02226525195053, "CICLOSPORIN": 3.7665746743527664, "CIMZIA": 4.328978148542721, "COSENTYX": 39.089396612690194, "ENBREL": 10.666175334870616, "HUMIRA": 3.5526512434833557, "METHOTREXATE": 3.1153764683877943, "SIMPONI": 3.2537134148488844}
\ No newline at end of file
+{"SOLIRIS": 46.72572520895088, "null": 0.7779111359602272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2859.json
index ad9a8d855c5..fac1a7dd83b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2859.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2859.json
@@ -1 +1 @@
-{"null": 1.4012002052499064}
\ No newline at end of file
+{"SOLIRIS": 92.95526397805294, "null": 0.3890390994224157}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/286.json
index df7c55eaf87..97fffd32110 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/286.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/286.json
@@ -1 +1 @@
-{"null": 2.0495228807388}
\ No newline at end of file
+{"null": 2.13850740174584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2860.json
index a625e512084..6f67beeb341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2860.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2860.json
@@ -1 +1 @@
-{"ABILIFY": 3.2189303916592835, "ARIPIPRAZOLE": 3.533273689343762, "CYMBALTA": 1.4301061984283696, "GARDASIL": 1.2537747152092782, "HUMALOG": 1.9771583868185132, "KEPPRA": 2.9495723465806414, "OLANZAPINE": 2.615079368620928, "XYREM": 55.01823440148234, "ZYPREXA": 3.4983951516448752, "null": 3.5410476536119364}
\ No newline at end of file
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2861.json
index 50ee10927e9..325b05e2b49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2861.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2861.json
@@ -1 +1 @@
-{"IBUPROFEN": 30.363655225139127, "null": 2.7144895211211426}
\ No newline at end of file
+{"ABILIFY": 1.5393784386018947, "ACE": 9.776473580092135, "ACTOS": 0.6775116278378464, "ADALIMUMAB": 0.0133690147711876, "AIMOVIG": 0.0590872085766286, "ALL": 4.259953852420468, "ALPHA": 153.44599510511185, "ANALGESIC": 62.16154448832651, "ANGIOTENSIN": 35.925444641320624, "ANGIOTENSINCONVERTING": 94.20060036223455, "ANTIDEPRESSANT": 27.09054077122279, "ANTIDEPRESSANTS": 10.70798892837862, "ANTIHISTAMINE": 24.422629074771876, "ANTIMALARIALS": 264.4547767318826, "ANTIPLATELET": 158.5298852551079, "ANTIPSYCHOTIC": 93.52661870911469, "APIXABAN": 0.4055693404478621, "ARIPIPRAZOLE": 4.906436196439608, "ASENAPINE": 20.8823279788017, "ATAZANAVIR": 1.3483854562390851, "ATRIPLA": 0.0432837215639698, "BARBITURATES": 44.89813050372836, "BEDAQUILINE": 0.3334034343694952, "BENZODIAZEPINE": 61.5128329444677, "BENZODIAZEPINES": 23.4981743329371, "BETA": 108.4257044897281, "BETABLOCKER": 69.70506869533357, "BRINTELLIX": 2.343707860112936, "BRIVARACETAM": 1.119549257463506, "BUDESONIDE": 0.0984916434168582, "BUMETANIDE": 8.070966578345233, "BUPRENORPHINE": 1.8497304831675223, "CALCIUM": 34.59229557601386, "CARBIDOPA": 0.7260958088574464, "CARDIAC": 73.08718125273737, "CARIPRAZINE": 12.966666581606033, "CELECOXIB": 3.807880799507685, "CHAMPIX": 3.953088212387927, "CLOPIDOGREL": 1.944880030126984, "COMIRNATY": 0.0026396404930942, "COMTAN": 0.6976534659948972, "CYCLIC": 246.32742747638773, "CYMBALTA": 2.1041090162541183, "DARUNAVIR": 0.7068040614724784, "DEXAMETHASONE": 0.0709610303561131, "DIURETICS": 12.884982657373282, "DRUG": 35.94591267230228, "DULOXETINE": 25.12546769131355, "ELIQUIS": 0.0300206405807217, "EMPAGLIFLOZIN": 0.5928193558876758, "EMTRICITABINE": 0.713332315335954, "ESOMEPRAZOLE": 3.9232226087944686, "FENTANYL": 3.2752742785284084, "FYCOMPA": 1.360558486627625, "GARDASIL": 0.0704288230784428, "GLIBENCLAMIDE": 10.453529395671554, "GLUCAGON": 4.21177125709921, "GUANFACINE": 17.75102651727286, "HARVONI": 0.2586397260446694, "HUMALOG": 0.1275552370243318, "HYDROCHLOROTHIAZIDE": 4.547487303790689, "IBUPROFEN": 17.919053205852165, "INSULIN": 1.0459829072920004, "INTRONA": 1.9229713203534289, "INVEGA": 2.699931216496802, "IRBESARTAN": 1.09648437938078, "IRON": 4.634331148847398, "JANUMET": 0.1175672305395663, "JANUVIA": 0.1056861482857467, "KAFTRIO": 0.3884220789972638, "KALETRA": 0.1354278522817946, "KEPPRA": 0.6500760656313023, "LACOSAMIDE": 1.8638313039920955, "LANTUS": 0.0728867345835996, "LATUDA": 3.998016621997286, "LAXATIVES": 27.82921476166062, "LEFLUNOMIDE": 0.5331184741888376, "LEVETIRACETAM": 2.8115928000046866, "LEVODOPA": 2.3224432487173647, "LEVOFLOXACIN": 0.1578002163814781, "LINACLOTIDE": 85.5565137713835, "LOXAPINE": 2.830872298326427, "LURASIDONE": 25.219381301105365, "LYRICA": 0.6906433830216946, "MELATONIN": 4.101722038191308, "METFORMIN": 1.7939498604291737, "METHOTREXATE": 0.1102790637907911, "MIDAZOLAM": 2.421464291279505, "MUSCLE": 25.99729175529041, "NALOXONE": 2.1268667739415084, "NATEGLINIDE": 39.61870617487866, "NOT": 14.45282963815395, "OLANZAPINE": 9.061689690199898, "OLYSIO": 0.3686920531466459, "OPIOID": 119.96856128627208, "OPIOIDS": 13.00993482950356, "OXYBUTYNIN": 11.62991809039005, "PALIPERIDONE": 6.398956770838945, "PANTOPRAZOLE": 5.552779854696427, "PEGASYS": 0.5363248727847335, "PEGINTERFERON": 0.2326546006799689, "PEGINTRON": 0.8717682383806973, "PIOGLITAZONE": 14.62938634371715, "PLAVIX": 0.0439263970837789, "PREGABALIN": 8.074405483357808, "PROPRANOLOL": 11.442193017488036, "RANOLAZINE": 2.134025833840385, "RASAGILINE": 11.766182062559732, "REBETOL": 0.5928727596804917, "RISPERIDONE": 1.7744036986867824, "RIVAROXABAN": 12.419771711266495, "SERTRALINE": 14.871168272252872, "SIFROL": 0.4950485766097374, "SILDENAFIL": 3.9511749090980097, "SITAGLIPTIN": 19.66567288460777, "SKELETAL": 102.5292937671624, "SPIKEVAX": 0.0040162440029946, "SSRI": 53.30328829485575, "STELARA": 0.072780671379015, "SUBOXONE": 1.628740255848925, "SUTENT": 0.0181369528262811, "SYCREST": 1.5781867768590234, "TAMIFLU": 0.9111811152599596, "TELMISARTAN": 1.276119214008937, "TRAZODONE": 72.86622490574653, "TRICYCLIC": 82.87532264830675, "UNKNOWN": 31.485302076391086, "UNSPECIFIED": 70.40448377862401, "VALSARTAN": 1.886478005785172, "VARENICLINE": 4.595000183765949, "VAXZEVRIA": 0.0025452299398168, "VIAGRA": 0.1236567099616558, "VICTOZA": 0.2066780809844597, "VIMPAT": 0.4707483539101973, "VORTIOXETINE": 11.438855501790384, "XEPLION": 4.033331950118586, "ZALEPLON": 83.49165343645447, "ZIPRASIDONE": 51.41570996496304, "ZYPADHERA": 0.5702436631825244, "ZYPREXA": 2.7594506840860022, "null": 5.355506621282687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2862.json
index fb898709724..dfa8ea67319 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2862.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2862.json
@@ -1 +1 @@
-{"null": 1.7393302457942292}
\ No newline at end of file
+{"BOSULIF": 17.375924349815794, "BUPIVACAINE": 19.02360718915157, "COMIRNATY": 0.8933081607303427, "CYMBALTA": 2.194015371822212, "GARDASIL": 24.36070927443529, "IMATINIB": 36.95708549824349, "LYRICA": 4.574626162044443, "OMALIZUMAB": 4.3960860695285895, "QUTENZA": 64.1071452450929, "SPIKEVAX": 0.4645000508887169, "TASIGNA": 5.616529427675848, "TOZINAMERAN": 0.4319508699022271, "VAXZEVRIA": 0.1531796291828455, "null": 0.8853639654229402}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2863.json
index 3d34d774a97..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2863.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2863.json
@@ -1 +1 @@
-{"ONCASPAR": 1281.4118526107254}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2864.json
index 7d3d1269166..609b9c9ba08 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2864.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2864.json
@@ -1 +1 @@
-{"null": 1.431887213883862}
\ No newline at end of file
+{"COMIRNATY": 1.3130548053732969, "null": 0.4938881778183323}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2865.json
index 46c82158b3d..b2bd26275e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2865.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2865.json
@@ -1 +1 @@
-{"ATRIPLA": 2.619683825434016}
\ No newline at end of file
+{"ADCIRCA": 19.1108755301152, "ADEMPAS": 16.339972209523477, "ARANESP": 1.8166905502402184, "BUPIVACAINE": 8.585489273048141, "BYETTA": 3.262646937582889, "CINRYZE": 38.655144476502414, "COMIRNATY": 0.0234739141647099, "CYMBALTA": 0.5553717793483034, "CYTARABINE": 2.380440390420163, "ELIQUIS": 1.361421919587363, "ENTRESTO": 1.9108938024228053, "FENTANYL": 1.4965843056201111, "FORSTEO": 2.4956854580937464, "HUMALOG": 1.4033420547957025, "JANUVIA": 2.7312366393826726, "KEPPRA": 1.3079857973906366, "LANTUS": 0.9642458934055936, "NOVOSEVEN": 31.177213612479523, "OPSUMIT": 17.735436949422116, "REVATIO": 6.461475233805495, "SIMPONI": 7.700278955182457, "SPIKEVAX": 0.0560987605294146, "TRACLEER": 15.85797292867412, "null": 2.0714497214234227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2866.json
index 1fdacf573f4..2b2983a1308 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2866.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2866.json
@@ -1 +1 @@
-{"null": 1.0385229700242975}
\ No newline at end of file
+{"GARDASIL": 25.68297293376917, "null": 2.2585176960458164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2867.json
index bfcb3710f66..68e4801ea27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2867.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2867.json
@@ -1 +1 @@
-{"AVAMYS": 53.68464120784988, "DEXAMETHASONE": 10.01910061325164, "FASENRA": 88.22478485582131, "MEPOLIZUMAB": 237.43153632357004, "NUCALA": 47.422038003134645, "TOBRAMYCIN": 74.65641238920456}
\ No newline at end of file
+{"null": 3.7308191524854224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2868.json
index 63c448b2df2..dca3aea6792 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2868.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2868.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 5.29892588856096, "BUDESONIDE": 17.98692140487221, "DOCETAXEL": 10.163486851016634, "FASENRA": 14.512679392957857, "MEPOLIZUMAB": 21.94766037833736, "METHOTREXATE": 34.62703478432783, "NUCALA": 10.040416379536142, "OLANZAPINE": 5.101034076783346, "PEGASYS": 2.1210880057740438, "VARENICLINE": 178.9103912301595}
\ No newline at end of file
+{"null": 2.5442359161660035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2869.json
index 82c2061a60a..f7b64704cf8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2869.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2869.json
@@ -1 +1 @@
-{"ACLIDINIUM": 11.046773925916243, "ADCIRCA": 4.262994294792495, "ALEMTUZUMAB": 5.139019804658902, "AVAMYS": 6.95119126830032, "AZATHIOPRINE": 6.863199150323931, "BENRALIZUMAB": 11.950311997483542, "BUDESONIDE": 13.470282246746612, "CLOPIDOGREL": 1.7663385068922044, "COSENTYX": 1.6002087055949263, "CUBICIN": 23.656250907188188, "DUPILUMAB": 29.744665725515546, "DUPIXENT": 16.1346065222669, "ENTRESTO": 1.5453925212584985, "ERLEADA": 9.165166724221438, "FASENRA": 46.630476579515296, "FLUTICASONE": 9.27208295334308, "GIOTRIF": 116.62312369149006, "IBUPROFEN": 1.6874864873430926, "ISENTRESS": 3.574002247098945, "JANUVIA": 2.296252776057526, "KEYTRUDA": 2.956941509458654, "LEVOFLOXACIN": 2.4818682441324733, "MEPOLIZUMAB": 15.156526961053652, "METHOTREXATE": 6.440821610108237, "MICAFUNGIN": 26.70384928505748, "NOT": 2.407488415386257, "NUCALA": 16.00585565035049, "OLANZAPINE": 1.206470648204114, "OMALIZUMAB": 10.152866744461052, "OPDIVO": 4.270700288981342, "PEGINTRON": 1.4047162110856393, "PLAVIX": 1.3856943772580723, "ROACTEMRA": 2.203292143590022, "TAGRISSO": 1.6189663068143547, "TASIGNA": 1.132754761517971, "UMECLIDINIUM": 147.81126690164493, "VARENICLINE": 26.621213362331087, "XOLAIR": 5.476101458511203, "null": 1.5382874920977447}
\ No newline at end of file
+{"SIXMO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/287.json
index c1b8e9a4444..766ec68438a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/287.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/287.json
@@ -1 +1 @@
-{"null": 2.743087324668022}
\ No newline at end of file
+{"null": 1.7690326142898176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2870.json
index 955d4cc229b..a1919ea3fff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2870.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2870.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.155014487374025}
\ No newline at end of file
+{"RUCONEST": 124.7474474094501, "SUBOXONE": 12.301752687092277, "null": 1.2568639635023566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2871.json
index da60cc6498d..82481e47ef2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2871.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2871.json
@@ -1 +1 @@
-{"CUBICIN": 47.62854443960199, "KEYTRUDA": 6.68440829051359, "null": 1.383254093591616}
\ No newline at end of file
+{"ALEMTUZUMAB": 83.89553257896878, "ANAKINRA": 90.51709892248056, "CICLOSPORIN": 62.399497887245936, "EXJADE": 32.829084814980405, "null": 0.2339376330575233}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2872.json
index cde682b5861..c1bbb4b698c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2872.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2872.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.5101718065486416, "ADENURIC": 4.997639530733817, "AERIUS": 5.639074145365703, "AMIKACIN": 9.349164823905468, "APROVEL": 5.604101010142409, "ARANESP": 1.3508673949713044, "ARIPIPRAZOLE": 1.265554521525437, "ARIXTRA": 6.687854768100896, "ATAZANAVIR": 1.021758277642843, "AVAMYS": 1.2238631981151489, "AZTREONAM": 19.18348230403525, "BINOCRIT": 8.870304500094988, "BRILIQUE": 2.9476613279395525, "BUDESONIDE": 14.72099839335945, "CANCIDAS": 7.270462614918485, "CASPOFUNGIN": 3.2641881468700875, "CHOLESTAGEL": 30.398701899431316, "CLOPIDOGREL": 1.5276559444877558, "COAPROVEL": 2.918363279119889, "COMBIVIR": 2.550146602546409, "COMPLEMENT": 41.24530569511127, "COTELLIC": 2.8094752618794923, "CUBICIN": 32.32341475709163, "DAPTOMYCIN": 6.718209619446062, "DESLORATADINE": 3.844574625483778, "DIFICLIR": 20.724558211876207, "DUPIXENT": 4.676493960660832, "EBIXA": 5.388159224928923, "EFIENT": 3.867433900711243, "EMTRICITABINE": 1.9281037733099768, "ENOXAPARIN": 2.7705884442892934, "ENTYVIO": 1.4208082402453497, "EPIVIR": 1.900993231872388, "ESOMEPRAZOLE": 3.7998942047229662, "EUCREAS": 3.235380510740385, "FASENRA": 2.9617839800750385, "FEBUXOSTAT": 3.658325672210787, "GANCICLOVIR": 1.740087660995837, "IBUPROFEN": 1.046850255478463, "INCIVO": 4.810070668988482, "IPILIMUMAB": 1.3433577119300888, "IRBESARTAN": 5.285994348254948, "ISENTRESS": 5.480044544994774, "KAFTRIO": 2.3575343863616145, "KEPPRA": 2.706130257589919, "KEYTRUDA": 1.0264557094851647, "KIVEXA": 5.088487823700116, "LEFLUNOMIDE": 1.139039659569527, "LEVETIRACETAM": 3.857571960361709, "LEVOFLOXACIN": 1.7070630053273452, "LOPINAVIR": 5.169270037166421, "LYRICA": 1.0625416078157024, "MABTHERA": 1.359091509757863, "MEPOLIZUMAB": 2.253313289091563, "METFORMIN": 3.779736757670315, "MICARDIS": 1.7673096674279531, "MIDAZOLAM": 1.3296266518200723, "MIMPARA": 2.0786496488732835, "NORVIR": 2.248148411607312, "NOVONORM": 10.36986542694903, "NUCALA": 9.331775714589345, "OLANZAPINE": 1.6771916340650934, "OPDIVO": 1.9180168858009168, "PANTOPRAZOLE": 7.126923951347549, "PEGINTERFERON": 1.2568279784940963, "PLAVIX": 1.7689786154309488, "PREGABALIN": 5.769549343877478, "PROTELOS": 19.64351038865956, "RASILEZ": 1.4649127173414238, "RENVELA": 31.80448542443745, "REVLIMID": 2.187058386980683, "ROACTEMRA": 2.520556594026388, "SUFENTANIL": 6.226639698414206, "TEMODAL": 2.0849875804530624, "TOBRAMYCIN": 4.763391445780803, "VFEND": 1.4746274770275394, "VIMPAT": 1.9539342383704543, "VIRAMUNE": 7.086952592395356, "XARELTO": 1.120289152116781, "XOLAIR": 1.9128640759041449, "YERVOY": 1.1964238695878873, "ZELBORAF": 5.716945552966066, "null": 2.800096310678105}
\ No newline at end of file
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2873.json
index 8ee67653ece..7fdaba98e55 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2873.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2873.json
@@ -1 +1 @@
-{"AVAMYS": 69.19772567015505, "BUDESONIDE": 119.2452919568111, "MEPOLIZUMAB": 58.02955460244365}
\ No newline at end of file
+{"VFEND": 48.99452248144711, "null": 0.3927857668761199}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2874.json
index 51b235b165c..a690cbaf555 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2874.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2874.json
@@ -1 +1 @@
-{"null": 1.1232634885918429}
\ No newline at end of file
+{"ARANESP": 22.164458039072564, "BASILIXIMAB": 385.94920878239367, "CELLCEPT": 27.63145745664613, "CICLOSPORIN": 68.822805499464, "MYCOPHENOLATE": 96.10346077841476, "SOLIRIS": 8.115480122109352, "TACROLIMUS": 74.50705244939448, "null": 0.564258688222293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2875.json
index e8b253e56ba..9836666b7e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2875.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2875.json
@@ -1 +1 @@
-{"LEVETIRACETAM": 128.51419354834565, "null": 2.792889305099717}
\ No newline at end of file
+{"null": 0.32278776867891}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2876.json
index a974e062a2c..4d1f62646e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2876.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2876.json
@@ -1 +1 @@
-{"KEYTRUDA": 13.065277410112246, "PEMBROLIZUMAB": 70.56382415727057}
\ No newline at end of file
+{"CICLOSPORIN": 118.31902000369108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2877.json
index f4c4878aec6..373f092764b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2877.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2877.json
@@ -1 +1 @@
-{"ANORO": 163.9112214138665, "APIXABAN": 24.45881786595038, "AZATHIOPRINE": 23.017416920981383, "BENRALIZUMAB": 13.787285786964585, "BUDESONIDE": 6.107953468187922, "FASENRA": 38.27959933131371, "MEPOLIZUMAB": 5.617161210626048, "METHOTREXATE": 8.405528270328112, "NUCALA": 10.801868831141098, "OMALIZUMAB": 8.365093057384868, "XOLAIR": 16.741397252534668, "null": 2.8659241770403114}
\ No newline at end of file
+{"ATRIPLA": 4.588184112167369, "BONVIVA": 22.27329326575435, "COMIRNATY": 0.0261297566468846, "CYMBALTA": 0.7933989284371071, "ELIQUIS": 1.342490439292453, "EVENITY": 111.38521889177213, "EVISTA": 76.83100643839943, "IBRANCE": 1.013436457515881, "STRIBILD": 5.807050585340042, "TEDUGLUTIDE": 119.30276811746002, "TRUVADA": 5.565300872796311, "XELJANZ": 1.5874448350225068, "XTANDI": 4.798983212938757, "ZOMETA": 42.66425174097731, "null": 1.373628867738039}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2878.json
index 8097d4d06f6..0fd6a3865e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2878.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2878.json
@@ -1 +1 @@
-{"null": 1.8820822753636484}
\ No newline at end of file
+{"null": 2.8817031099828445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2879.json
index 69de6b96e86..5db20dc5145 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2879.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2879.json
@@ -1 +1 @@
-{"EMPAGLIFLOZIN": 54.64717491053017, "METHOTREXATE": 77.54521044076739, "null": 2.091186638446401}
\ No newline at end of file
+{"null": 2.846137987720282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/288.json
index 7d4303139fd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/288.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/288.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 101.91377913855784, "null": 1.8806373189837036}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2880.json
index 5a46b5ca54d..d98bc0e779a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2880.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2880.json
@@ -1 +1 @@
-{"ADCIRCA": 54.69795916037025, "GARDASIL": 9.935904510541976, "XOLAIR": 6.299321516974139, "null": 3.326418747837527}
\ No newline at end of file
+{"ABILIFY": 66.09061069008744, "SIFROL": 242.80041011613463, "null": 1.305921489910067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2881.json
index b3646e9a51a..4bcbb3f5708 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2881.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2881.json
@@ -1 +1 @@
-{"null": 3.2627323947230757}
\ No newline at end of file
+{"ABILIFY": 56.89563454034301, "AZILECT": 134.35493495481504, "COMTAN": 86.35070521208279, "ENTACAPONE": 140.37564444815737, "LEVODOPA": 252.64324083253203, "SIFROL": 722.4348656547571, "null": 1.2144211505221023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2882.json
index d1094f2df56..2162c9942a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2882.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2882.json
@@ -1 +1 @@
-{"ADCIRCA": 10.657785189773763, "CLOPIDOGREL": 1.8748984982712589, "CUBICIN": 682.0369350743701, "ENTYVIO": 3.9585279144011016, "LEVOFLOXACIN": 4.489157053681913, "METHOTREXATE": 11.611539858685896, "PLAVIX": 2.7188848092557523, "SIMPONI": 2.091358311208169, "STELARA": 3.113102111251873, "XOLAIR": 1.0835798256126834, "null": 1.8496716914796327}
\ No newline at end of file
+{"MVASI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2883.json
index 715d689c1e2..c301e5ca17e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2883.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2883.json
@@ -1 +1 @@
-{"CUBICIN": 641.1133176788422, "LEVOFLOXACIN": 7.28086587239545, "null": 2.0261695015722414}
\ No newline at end of file
+{"SPIKEVAX": 24.09456695083029, "null": 0.1300183592438909}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2884.json
index b3ab81a7b7d..654e6f24f4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2884.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2884.json
@@ -1 +1 @@
-{"COMIRNATY": 1.5317794074230324, "COSENTYX": 4.008275732381999, "ENBREL": 3.700376135537051, "TRUVADA": 1.2579161907156309, "ZOSTAVAX": 4.426158506678191}
\ No newline at end of file
+{"SPIKEVAX": 8.929550944354656, "null": 0.8071462026075795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2885.json
index ac514cc35a7..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2885.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2885.json
@@ -1 +1 @@
-{"AZARGA": 1291.3632998222286, "AZOPT": 844.2336356273643, "IBUPROFEN": 8.210015589831482, "LEVOFLOXACIN": 9.238672864122984, "null": 2.114081631073484}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2886.json
index feb84a557f1..56a89d2ecd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2886.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2886.json
@@ -1 +1 @@
-{"NEXAVAR": 10.292004997085044, "null": 1.528552735334795}
\ No newline at end of file
+{"BUDESONIDE": 2.108496394900021, "CICLOSPORIN": 5.864067194356603, "COMIRNATY": 0.0672932474852581, "CUBICIN": 20.141778659943853, "CYTARABINE": 8.585450407730658, "KEYTRUDA": 1.7012547774642883, "SPIKEVAX": 0.2776055934168286, "SUTENT": 0.9276875795340648, "XOLAIR": 5.262822873659927, "null": 1.5541258128681623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2887.json
index 8b9253bd261..459b6758f1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2887.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2887.json
@@ -1 +1 @@
-{"null": 2.330291924802159}
\ No newline at end of file
+{"SPIKEVAX": 5.431295484531295, "VAXZEVRIA": 3.9944670922638728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2888.json
index a89747f3ee0..6d286b7af2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2888.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2888.json
@@ -1 +1 @@
-{"null": 5.173761806797733}
\ No newline at end of file
+{"SPIKEVAX": 9.19864459813618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2889.json
index 2139da9c30b..ec17a0fd971 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2889.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2889.json
@@ -1 +1 @@
-{"FORXIGA": 13.382194469434127, "ISENTRESS": 42.35530313205707, "JARDIANCE": 7.486927317012153, "KAFTRIO": 26.201847336015497}
\ No newline at end of file
+{"SPIKEVAX": 28.474135998060078}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/289.json
index ee200c5e855..60d2c04ddd4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/289.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/289.json
@@ -1 +1 @@
-{"null": 2.936222849208289}
\ No newline at end of file
+{"COMIRNATY": 4.782743190788541, "HIZENTRA": 8.913697627565753, "MMRVAXPRO": 3.4670877470531285, "MODERNA": 2.869194137840116, "ROACTEMRA": 4.554529500234091, "SPIKEVAX": 2.0893422325320654, "VAXZEVRIA": 1.942265235464999, "null": 0.3114566028419257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2890.json
index d22303d1c17..d39d66a913d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2890.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2890.json
@@ -1 +1 @@
-{"ELIQUIS": 17.191654366998073}
\ No newline at end of file
+{"ENTRESTO": 83.59527123745303, "null": 1.039154314739532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2891.json
index f59d0989755..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2891.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2891.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 126.92865730341845}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2892.json
index 67390948dfc..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2892.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2892.json
@@ -1 +1 @@
-{"ABATACEPT": 4.412475309196731, "ARAVA": 2.0426927597005764, "CICLOSPORIN": 1.0696029727182843, "CLOPIDOGREL": 6.030895634193687, "ENBREL": 2.0186486671499395, "FORXIGA": 3.3412907780508707, "JANUMET": 2.1303969319188383, "JARDIANCE": 1.3794625504483478, "KEPPRA": 1.5459693931035765, "METHOTREXATE": 4.274281154185458, "PEGASYS": 1.277874612722235, "PLAVIX": 1.3863092205871204, "XELJANZ": 1.025090687509595, "null": 1.5353248701044568}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2893.json
index b93866f0acf..3b86624b695 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2893.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2893.json
@@ -1 +1 @@
-{"null": 2.4902575120634944}
\ No newline at end of file
+{"GARDASIL": 47.5232163302004, "SPIKEVAX": 7.802456915609422}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2894.json
index 1e2ec364e30..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2894.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2894.json
@@ -1 +1 @@
-{"ROACTEMRA": 18.876635679650526, "null": 1.5956392690699663}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2895.json
index 5a6d77e4d77..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2895.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2895.json
@@ -1 +1 @@
-{"LACOSAMIDE": 198.26593683567603, "LEVETIRACETAM": 65.6393091691687}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2896.json
index eb65d626dc6..8277334983c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2896.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2896.json
@@ -1 +1 @@
-{"ABATACEPT": 4.1249858735047225, "ADALIMUMAB": 1.6291532304982146, "AERIUS": 1.7232383234570303, "AIMOVIG": 6.548548839867366, "APREMILAST": 10.010226227238338, "ASPARAGINASE": 2.3727635501806965, "AVAMYS": 1.9632857681923055, "BEDAQUILINE": 1.5261111042594409, "BETAFERON": 1.0546256140113182, "BEXSERO": 1.4958415737638249, "BIKTARVY": 1.2378046692284497, "BRINTELLIX": 1.5494630436730326, "BRIVARACETAM": 11.911218636710496, "BRIVIACT": 8.227052707751023, "BUCCOLAM": 15.45352692017746, "CANNABIDIOL": 7.822489278520348, "CHAMPIX": 2.1944611036790267, "CIRCADIN": 3.9065289112923858, "DIACOMIT": 14.508609668481167, "EBIXA": 10.046585547440008, "EMEND": 1.1025746723437884, "EPIDYOLEX": 11.781796004675943, "ERLEADA": 1.2059756764843448, "EXELON": 5.025424609617815, "FAMPYRA": 7.162933786473334, "FYCOMPA": 9.16621615839612, "GARDASIL": 2.526118706123407, "HEMLIBRA": 1.703565690875214, "INFANRIX": 3.900284836279887, "INOVELON": 11.840997356961102, "INVANZ": 6.104987061503228, "KAFTRIO": 1.346902371557584, "KEPPRA": 13.630823714401307, "LACOSAMIDE": 17.709001398372894, "LEVETIRACETAM": 16.666419495506936, "LEVOFLOXACIN": 1.818588476525205, "MEKINIST": 1.028361859188569, "MIDAZOLAM": 1.7078967979736, "MIMPARA": 2.533047565713162, "NIMENRIX": 1.2542381108962244, "NORVIR": 1.3098354001852133, "OLANZAPINE": 1.1468679718277446, "PERAMPANEL": 15.057648403573708, "PREGABALIN": 1.350864454075957, "PREVENAR": 1.5207468654615897, "PROTELOS": 2.3252081227075263, "RISPERIDONE": 1.5406681232415074, "SPINRAZA": 1.594047140977376, "TAMIFLU": 1.3759652544676797, "TEMODAL": 2.535265624932308, "TEMOZOLOMIDE": 1.0062329035437534, "TWINRIX": 1.5990083915118187, "VFEND": 1.1887275839678146, "VIGABATRIN": 5.661081061762026, "VIMPAT": 25.420998187503887, "VORICONAZOLE": 1.1247022628787613, "XTANDI": 1.2597196716557812, "ZAVESCA": 5.036546526054486, "ZONISAMIDE": 11.425929562407545, "ZYPREXA": 1.3148201643029611, "null": 2.0959722503844254}
\ No newline at end of file
+{"APREPITANT": 490.7821148960112, "SPIKEVAX": 6.508839409482139}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2897.json
index 05007358052..7b5b28b3c8f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2897.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2897.json
@@ -1 +1 @@
-{"KEPPRA": 42.57156213248659, "null": 1.9407976366233173}
\ No newline at end of file
+{"APREPITANT": 127.24802931445866, "DEXAMETHASONE": 19.353507199271213, "SPIKEVAX": 6.101362252824369, "null": 0.3579751226535835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2898.json
index 8c87eb6b5d1..85f4041c5e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2898.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2898.json
@@ -1 +1 @@
-{"KEPPRA": 15.360029796129202, "null": 1.7316606547931848}
\ No newline at end of file
+{"SPIKEVAX": 28.53033660629104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2899.json
index 3713d856244..0c62d5e03cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2899.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2899.json
@@ -1 +1 @@
-{"LEVETIRACETAM": 111.82760703308053, "null": 1.2763921387255468}
\ No newline at end of file
+{"ADCIRCA": 10.458245977333153, "ADEMPAS": 10.726858528952008, "AFINITOR": 7.3958960701623395, "AIMOVIG": 0.7602816044487558, "CICLOSPORIN": 2.1700212109080086, "COMIRNATY": 1.9295037016207397, "COSENTYX": 8.247259170029082, "CYMBALTA": 0.9138181966835732, "DOCETAXEL": 1.9553977718837765, "DOXORUBICIN": 3.822329859486565, "ELIQUIS": 0.3865905714941524, "ENTRESTO": 4.149549186116058, "EXFORGE": 4.455714339930749, "EXJADE": 2.2500085031681465, "GARDASIL": 0.4022420946568307, "JAKAVI": 18.304296543207776, "KEPPRA": 0.781271455742378, "MEKINIST": 3.571072465374731, "METFORMIN": 26.42028381085322, "OMALIZUMAB": 4.17499954418396, "OPSUMIT": 16.376895619762994, "PASIREOTIDE": 143.31916048400728, "RUXOLITINIB": 10.24179554525715, "SPIKEVAX": 0.9518737410961552, "TAMIFLU": 1.972932383035177, "TASIGNA": 9.479186389539391, "TRACLEER": 11.830409118923937, "VAXZEVRIA": 0.2374601597559215, "VOTRIENT": 1.006366801348131, "XOLAIR": 3.315331822590602, "null": 0.7067744280440013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/29.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/29.json
index af76370af9e..9c21761c4fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/29.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/29.json
@@ -1 +1 @@
-{"ABILIFY": 3.675425746243086, "AERIUS": 3.0262828814170697, "ANTIBIOTICS": 7.656193957164304, "ARIPIPRAZOLE": 4.064997406100146, "AZILECT": 4.430084591115952, "BORTEZOMIB": 3.433742445346988, "BRINTELLIX": 1.254460219561561, "BRIVARACETAM": 16.6327666826383, "BRIVIACT": 4.2286544214840704, "BUMETANIDE": 6.596792511968096, "BUPIVACAINE": 3.0589886708459497, "BUPRENORPHINE": 1.8786574483092504, "CARBIDOPA": 3.615431389128957, "CHAMPIX": 12.905389238812257, "COMBIVIR": 1.0432628919256517, "COMTAN": 7.507020106136249, "CYMBALTA": 2.5786160897649104, "DULOXETINE": 2.33540262003294, "EPIDYOLEX": 15.059179866566067, "FENTANYL": 1.6361554899865745, "FYCOMPA": 6.167782667245704, "HYDROCORTISONE": 1.1855081258491167, "INFANRIX": 2.6070964307545883, "IRBESARTAN": 1.882761072022387, "KAFTRIO": 2.1434377719629483, "KEPPRA": 5.757633111326372, "LATUDA": 7.180708771614565, "LEVETIRACETAM": 6.499697901118006, "LEVODOPA": 3.506483117110069, "LURASIDONE": 15.157694377695112, "LYRICA": 2.304746112151262, "MEMANTINE": 7.068974726541299, "MIDAZOLAM": 2.134830258057685, "MMRVAXPRO": 1.84008611476073, "NIMENRIX": 1.4833514539414658, "OLANZAPINE": 5.2419048816385, "OXYBUTYNIN": 3.974543768811076, "PEGINTRON": 1.4386580562090516, "PREGABALIN": 1.3028041767377103, "PREVENAR": 2.0316697162902413, "RISPERIDONE": 7.068079384800062, "SIFROL": 5.513847270309444, "SILDENAFIL": 1.254309707310444, "STALEVO": 3.405736030382148, "SUBOXONE": 2.2618159254331727, "TAMIFLU": 114.07796883334296, "VFEND": 1.4722529716014197, "VIMPAT": 4.281961212219553, "XYREM": 2.562222455144273, "ZONISAMIDE": 10.15880150495769, "ZYPADHERA": 4.974195543518177, "ZYPREXA": 3.566399861795604, "null": 2.1795503744548177}
\ No newline at end of file
+{"null": 0.5610331033905649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/290.json
index 4314ffa2c64..efcb145d8f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/290.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/290.json
@@ -1 +1 @@
-{"null": 1.016791246989776}
\ No newline at end of file
+{"KEYTRUDA": 2.963205752341145, "null": 10.117649540096291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2900.json
index 9b8cdd727f4..b956764c7a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2900.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2900.json
@@ -1 +1 @@
-{"null": 1.1050395043329635}
\ No newline at end of file
+{"AFINITOR": 9.225177086773352, "ALISKIREN": 66.92154223453393, "CICLOSPORIN": 7.47337822559472, "COMIRNATY": 0.1516745853978989, "COSENTYX": 2.953300188422351, "EXJADE": 12.400106385308838, "JAKAVI": 4.967769080767834, "MEKINIST": 4.15502629558916, "METFORMIN": 22.234402459292085, "NOVOSEVEN": 1018.7300870919788, "OPSUMIT": 8.338556120718591, "TASIGNA": 13.893238797132778, "TRACLEER": 7.660170385690843, "VAXZEVRIA": 0.2263878730211524, "null": 0.7761493879685543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2901.json
index d3c2bfe2526..c1e927a9389 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2901.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2901.json
@@ -1 +1 @@
-{"null": 6.249107449882757}
\ No newline at end of file
+{"COMIRNATY": 3.212988547658664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2902.json
index 612fe7b5f21..9ace3b94184 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2902.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2902.json
@@ -1 +1 @@
-{"null": 4.047972505381089}
\ No newline at end of file
+{"ABILIFY": 3.608355271074654, "AIMOVIG": 22.56975883311453, "AUBAGIO": 1.6397386164369905, "AZATHIOPRINE": 3.739811926506416, "COMIRNATY": 0.1984986577781851, "CYMBALTA": 3.0039244848797506, "ELIQUIS": 0.6168380608688796, "ESOMEPRAZOLE": 14.393584506310788, "FENTANYL": 1.3079098036464205, "FIRDAPSE": 8.9172810656474, "GARDASIL": 7.596917342288229, "HUMALOG": 2.641647962907085, "IBRANCE": 1.084490279176621, "IRBESARTAN": 5.549178584198931, "KEPPRA": 3.8566864103780873, "LANTUS": 3.592900332394989, "LYRICA": 4.258260591748541, "SPIKEVAX": 0.4436995884028133, "SUBOXONE": 3.8670255307034016, "TOZINAMERAN": 0.8315987435784451, "VAXZEVRIA": 0.0968651828077622, "VIAGRA": 3.0928681978910766, "XELJANZ": 2.364832843242189, "null": 1.1760695259592673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2903.json
index 7f1d884f232..fa2d2f1093a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2903.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2903.json
@@ -1 +1 @@
-{"NUTROPIN": 882.160968263104, "SOMATROPIN": 722.4450930132522, "null": 4.130712470204268}
\ No newline at end of file
+{"ABACAVIR": 0.3991805132680624, "ABATACEPT": 2.790533834883867, "ABILIFY": 1.6239752307056583, "ACLASTA": 1.4050861579832, "ACLIDINIUM": 4.230613060217498, "ACTRAPID": 7.612795996865404, "ADALIMUMAB": 4.790400508088602, "ADCIRCA": 1.2237590739891362, "ADEMPAS": 1.8026238757866613, "ADENURIC": 0.4380185821740249, "ADVATE": 0.4589587198319227, "AERIUS": 1.0934923482058412, "AFINITOR": 0.2095541347104838, "AGOMELATINE": 3.023400683919979, "AIMOVIG": 0.807213544530841, "ALDARA": 0.9770651952579807, "ALEMTUZUMAB": 0.9215463376139102, "ALIMTA": 0.2142821849374577, "ALL": 0.6950020985436598, "ALPELISIB": 1.1348279429350296, "AMBRISENTAN": 1.62378781009876, "AMIKACIN": 3.7208174939073615, "AMINOSALICYLIC": 1.1456128804287329, "ANAKINRA": 2.6264943046005205, "ANIDULAFUNGIN": 7.618217268206459, "ANORO": 7.0194853904592005, "APIDRA": 0.6111734279661113, "APIXABAN": 1.1966239659035645, "APREMILAST": 2.8278864145491256, "APREPITANT": 6.533140997070747, "APROVEL": 0.5922791592781598, "APTIVUS": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2904.json
index f9dc8e231bf..48680ed2d6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2904.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2904.json
@@ -1 +1 @@
-{"EYLEA": 33.33842575754128, "GANCICLOVIR": 81.73674680202016, "ZOSTAVAX": 31.427946747425445}
\ No newline at end of file
+{"ATAZANAVIR": 21.73009974998799, "BUDESONIDE": 2.7108395083934798, "COMIRNATY": 0.148072678908421, "IRBESARTAN": 19.92712319398857, "XYREM": 21.35360636598173, "null": 3.366345480977145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2905.json
index f8085e10786..8f3ec54741b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2905.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2905.json
@@ -1 +1 @@
-{"ADCIRCA": 63.65494520700914, "APIDRA": 20.25263306984255, "ENBREL": 11.998422687703528}
\ No newline at end of file
+{"EFAVIRENZ": 86.96421101221651, "NAGLAZYME": 102.7254168767744, "null": 1.4904451449494331}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2906.json
index 9b5639814d9..32c71397287 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2906.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2906.json
@@ -1 +1 @@
-{"ADCIRCA": 2.460733512122954, "ADEMPAS": 1.9946167066311271, "ADVATE": 1.8625145005966728, "AERIUS": 1.9792753267855887, "AFINITOR": 2.656562792161421, "ALIMTA": 1.5757586052597663, "AMBRISENTAN": 3.0098741339023487, "ARIXTRA": 1.623601759363905, "AVAMYS": 5.292200363440197, "AVASTIN": 3.32755121769311, "AXITINIB": 1.0964845219292132, "BETMIGA": 1.1048333585584305, "BEVACIZUMAB": 5.9371275112743325, "BOCEPREVIR": 1.474611925274038, "BRILIQUE": 20.75962277496496, "BRINTELLIX": 1.2895432511752387, "CLOPIDOGREL": 6.042068347876902, "COVID19": 1.2573468684832485, "DEFITELIO": 4.479242223399748, "DUOPLAVIN": 9.883986237489244, "EDOXABAN": 5.321295617415464, "EFIENT": 11.213833446579793, "ELIQUIS": 10.054806126937931, "ENOXAPARIN": 2.942008960374096, "GREPID": 5.038003607299718, "HEMLIBRA": 4.401989015957592, "HERCEPTIN": 1.7207990506530682, "IBRANCE": 2.229376098586111, "INCIVO": 1.294247787687252, "INHIXA": 3.237120882360976, "INLYTA": 1.3405160539912062, "INTEGRILIN": 3.374395580793081, "IRESSA": 1.0502030538636988, "ISCOVER": 3.814543015058492, "KOVALTRY": 5.478776902851115, "LENVIMA": 1.84999153342096, "LIXIANA": 19.17672143604868, "MACITENTAN": 2.138690056870184, "NEXAVAR": 1.5449184233667037, "NOVOSEVEN": 1.1790354485322518, "NPLATE": 3.814291566420444, "OCTREOTIDE": 2.7555047985676877, "OFEV": 2.2470087561358683, "OPSUMIT": 1.626016724657838, "OZEMPIC": 2.592447551719012, "PEGASYS": 1.852503923075951, "PLAVIX": 10.48132167463632, "PRADAXA": 3.754822060273004, "PRASUGREL": 12.837270121920746, "REVATIO": 2.7122332664314617, "RIVAROXABAN": 3.593364127299268, "SILDENAFIL": 1.8429317959813427, "STIVARGA": 1.2616101297809403, "SUNITINIB": 2.618178916718264, "SUTENT": 3.755490667230447, "TAMIFLU": 1.197956152290092, "TICAGRELOR": 6.616247987252902, "TOPOTECAN": 1.477291067304778, "TORISEL": 1.5310893045186, "TRACLEER": 1.0134013169070042, "VAXZEVRIA": 1.3466469545623865, "VOTRIENT": 1.8743150082504705, "XARELTO": 10.310139729868803, "ZONISAMIDE": 1.6314336130282996, "ZYLLT": 15.19584620684367, "null": 1.1378598336830832}
\ No newline at end of file
+{"MODERNA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2907.json
index d16e395b34b..3daba883170 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2907.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2907.json
@@ -1 +1 @@
-{"ABATACEPT": 4.78309512281517, "ALEMTUZUMAB": 135.55232041199235, "BUDESONIDE": 13.848991843215988, "BUSULFAN": 153.67527001838934, "CELLCEPT": 8.169539732380766, "CICLOSPORIN": 32.3368581942304, "SOLIRIS": 10.655160517689186}
\ No newline at end of file
+{"null": 0.9035461002883736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2908.json
index bad2389daa1..9da552d92e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2908.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2908.json
@@ -1 +1 @@
-{"CELLCEPT": 18.95579463412055, "CICLOSPORIN": 20.47225462023441}
\ No newline at end of file
+{"null": 1.5045972803916627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2909.json
index 320bf3ddd87..5686c254b3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2909.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2909.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 59.39847357271024, "CELLCEPT": 43.23447531068427, "CICLOSPORIN": 27.08098622113249}
\ No newline at end of file
+{"EFAVIRENZ": 421.4681794148452, "null": 0.8565727309887768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/291.json
index afcb084bc58..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/291.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/291.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 14.725311616352537}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2910.json
index a66e046fc64..ec35a252f16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2910.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2910.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 29.32513532776924, "BUSULFAN": 22.55157131804581, "CELLCEPT": 33.48511724642814, "CICLOSPORIN": 74.86607433169681, "METHOTREXATE": 9.562356267342984}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2911.json
index b33d670e196..5c1122093b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2911.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2911.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 40.770837514778975, "AZATHIOPRINE": 15.582378315245045, "BASILIXIMAB": 35.947028146079234, "BUDESONIDE": 1.4137403336194518, "BUSILVEX": 98.65928912553773, "BUSULFAN": 47.91243412020574, "CAELYX": 8.937936264537738, "CELLCEPT": 24.436701442912987, "CICLOSPORIN": 63.28097470157935, "CYMBALTA": 1.0482740949703462, "CYTARABINE": 3.4555301212070413, "DEXAMETHASONE": 2.246561999745265, "ENTYVIO": 3.101855321832678, "GARDASIL": 3.587175413086636, "HUMAN": 4.6300469987518245, "JAKAVI": 7.063563575731819, "METHOTREXATE": 2.349490599655975, "MYCOPHENOLATE": 26.37805706020179, "RITUXIMAB": 4.091934294376123, "SIMPONI": 1.247537885491309, "STELARA": 1.6153700024866249, "TACROLIMUS": 14.84013748743892}
\ No newline at end of file
+{"KALETRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2912.json
index ee37b363480..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2912.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2912.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.0979362878468897, "ALEMTUZUMAB": 46.879622719835815, "AZACITIDINE": 21.448494226992747, "BUDESONIDE": 2.526336161558552, "BUSILVEX": 168.89007609724024, "BUSULFAN": 99.74191006602288, "CARMUSTINE": 30.197945431269453, "CELLCEPT": 5.893489588889363, "CICLOSPORIN": 21.55941880681132, "COMIRNATY": 1.3413693751151468, "DOXORUBICIN": 24.616525964638715, "JAKAVI": 4.17953228095932, "METHOTREXATE": 6.482839888090762, "MYCOPHENOLATE": 19.043328315297224, "RUXOLITINIB": 36.77429039852652}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2913.json
index 49095d308b6..55c409669be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2913.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2913.json
@@ -1 +1 @@
-{"CELLCEPT": 56.52770006020345, "CICLOSPORIN": 15.944615154789318}
\ No newline at end of file
+{"STELARA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2914.json
index b1b04e6db05..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2914.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2914.json
@@ -1 +1 @@
-{"ESOMEPRAZOLE": 3599.1438851289136}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2915.json
index 1759c4ba634..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2915.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2915.json
@@ -1 +1 @@
-{"ANTIHYPERTENSIVES": 30.072979219334247, "APROVEL": 3.527306741030409, "BETMIGA": 3.740623297324343, "BIKTARVY": 4.050412169837435, "BRINTELLIX": 5.4122021341339375, "BYETTA": 1.2947919864508246, "CHAMPIX": 1.6476692954584224, "CIALIS": 15.25580309549722, "COAPROVEL": 4.266488512177378, "CRIXIVAN": 1.8284509099137487, "CYMBALTA": 1.1669220625033525, "EFIENT": 3.6389916963788607, "ENZALUTAMIDE": 2.9694318195545573, "ESOMEPRAZOLE": 1.190757092336964, "EXFORGE": 6.240068436438871, "FORXIGA": 2.222560341064772, "FYCOMPA": 4.650333661325357, "GENVOYA": 3.774034089626056, "HUMALOG": 1.0910330833210768, "ICLUSIG": 5.06324363834545, "IRBESARTAN": 1.743893335945217, "ISENTRESS": 3.071741528128123, "JANUMET": 2.7958751879965567, "JANUVIA": 1.083892956873258, "JARDIANCE": 1.5627628456734035, "KEPPRA": 1.5012862615094564, "LATUDA": 4.246022239549406, "LYRICA": 1.3410507869662618, "MICARDIS": 1.593635842443602, "MICARDISPLUS": 11.784280346717562, "MIMPARA": 3.4881885459392232, "OLANZAPINE": 1.3586474168633254, "PANTOPRAZOLE": 1.9142269865620791, "PREGABALIN": 1.0859119630355203, "RASAGILINE": 41.3728581767196, "RINVOQ": 1.0665289188504516, "SILDENAFIL": 7.753459628164362, "SILODYX": 35.6252305452816, "SUBOXONE": 1.3027838171255404, "TASIGNA": 1.709285279908978, "TESTOSTERONE": 5.861588361794704, "TREMFYA": 4.588913489690294, "UROREC": 44.1891832651713, "VIAGRA": 14.16841436152582, "VIMPAT": 1.6901943927569738, "ZOSTAVAX": 1.9582073908288136, "ZYPADHERA": 1.113134939670971, "ZYPREXA": 3.8361869473422616, "null": 3.208301401869256}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2916.json
index a4f8e5c30b4..2f3f6768361 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2916.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2916.json
@@ -1 +1 @@
-{"CIALIS": 10.493819189325457, "IBUPROFEN": 2.044133451429554, "SILDENAFIL": 13.849516792828432, "VIAGRA": 5881.196160640347}
\ No newline at end of file
+{"null": 2.2579060792362884}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2917.json
index 7c6fca90ab9..9fb23051e89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2917.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2917.json
@@ -1 +1 @@
-{"ATAZANAVIR": 132.506042993111, "KALETRA": 43.67966280308951, "LOPINAVIR": 975.2989695225376, "RITONAVIR": 787.4455344018598, "null": 1.0970987001213142}
\ No newline at end of file
+{"KAFTRIO": 625.6582724179586, "null": 0.5623079634166885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2918.json
index 75b48fd7812..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2918.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2918.json
@@ -1 +1 @@
-{"BRILIQUE": 17.63518731158939, "INSULIN": 12.2897902084719, "PLAVIX": 14.104380110500095, "null": 2.5998609390397287}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2919.json
index b3ccec2437c..8187f4f09de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2919.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2919.json
@@ -1 +1 @@
-{"APREPITANT": 194.66640392393444, "CLOPIDOGREL": 3.279090839059202, "COSENTYX": 2.948777973245726, "PLAVIX": 4.324117920289487, "null": 2.217156186107702}
\ No newline at end of file
+{"COMBIVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/292.json
index 8d4584dfea6..60d7f959bb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/292.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/292.json
@@ -1 +1 @@
-{"ARAVA": 2.971992854367356, "ENBREL": 6.802785023101931, "null": 1.0109459209590992}
\ No newline at end of file
+{"COMIRNATY": 1.257134134241356, "VAXZEVRIA": 0.9836015721081878, "null": 0.3283976559475035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2920.json
index 2250873ce5f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2920.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2920.json
@@ -1 +1 @@
-{"APREPITANT": 14.993387411042413, "BOSULIF": 3.980380618077744, "BRINTELLIX": 2.308912628514747, "BYDUREON": 11.22169393058593, "BYETTA": 4.1031336814865575, "CHAMPIX": 1.3520953580538038, "CLOPIDOGREL": 2.8943102439115744, "DULAGLUTIDE": 14.119817142015128, "ESBRIET": 3.86903561573624, "FASLODEX": 1.074830828541275, "FORSTEO": 1.9503170125317857, "FULVESTRANT": 3.427008741726635, "IBRANCE": 1.5611007623539197, "OFEV": 1.8656600175241729, "OXYBUTYNIN": 8.387980509593854, "OZEMPIC": 13.088507119337809, "RYBELSUS": 36.38451289005084, "SAXENDA": 46.19149517450522, "SUTENT": 2.502786830929825, "TEDUGLUTIDE": 49.804557220690185, "TOVIAZ": 3.4894684076972378, "TRULICITY": 64.50965298380565, "VICTOZA": 19.834821393941635, "null": 1.2048153406215274}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2921.json
index eb9cd169c67..35098fa3d20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2921.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2921.json
@@ -1 +1 @@
-{"ALIMTA": 9.190805937962253, "APROVEL": 6.779553279918758, "AZATHIOPRINE": 4.114928242346909, "BETAFERON": 5.753397019313024, "CELLCEPT": 1.132471140480382, "CIMZIA": 1.2519857629031108, "COMIRNATY": 1.149406191059182, "COSENTYX": 5.607921656211831, "ENTRESTO": 2.421818471548661, "FASLODEX": 1.7359911048279182, "FORSTEO": 1.6644517736775395, "HUMIRA": 1.5060687092461913, "INCIVO": 3.220784653708336, "JAKAVI": 3.112637977200909, "LANTUS": 1.0903727960490812, "METHOTREXATE": 2.936882119576772, "PEGASYS": 1.081034333155739, "PEGINTERFERON": 2.00152995649778, "PEMETREXED": 8.459825764561852, "RINVOQ": 4.368873185481797, "ROACTEMRA": 20.866742332041056, "SHINGRIX": 2.025042717552456, "SIMPONI": 5.110595521457879, "SOLIRIS": 1.64932371983917, "SPIKEVAX": 1.9231991941831488, "STELARA": 7.554391563057245, "TRACLEER": 2.0635038695183754}
\ No newline at end of file
+{"ABATACEPT": 0.8704975995876951, "ADALIMUMAB": 2.062904774984414, "APIXABAN": 4.513339527799936, "APTIVUS": 65.95198645740592, "ARAVA": 11.89381855873356, "ASPARAGINASE": 5.850741515615895, "BUDESONIDE": 2.2528147131974734, "BUPRENORPHINE": 4.115276581720223, "CIMZIA": 0.6633628798591971, "COMBIVIR": 18.19216385537997, "COMIRNATY": 0.0149265764266412, "CYMBALTA": 0.4432441403393228, "DESCOVY": 11.764958294092825, "EMTRICITABINE": 6.176010083784889, "GARDASIL": 0.417160487788049, "KALETRA": 3.557357523119804, "KEPPRA": 1.9634905290752105, "LEVETIRACETAM": 4.2729897688882055, "OLANZAPINE": 1.316207194935632, "PEGASYS": 0.2780674468907195, "SUBOXONE": 3.179137207643681, "null": 3.268131433509941}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2922.json
index ca84f62d2ec..30879eb9508 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2922.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2922.json
@@ -1 +1 @@
-{"ABACAVIR": 3.145635412384758, "ABASAGLAR": 1.1144770077677255, "ADENURIC": 1.8362719911248608, "AERIUS": 1.6510318322621278, "AKYNZEO": 4.181759458317539, "ALDARA": 3.5086879954571586, "ALIGN": 6.745671411025831, "ALIMTA": 1.4018351102617297, "ALOXI": 1.191856037325377, "AMELUZ": 3.146547926884322, "AMINOSALICYLIC": 3.328677677800568, "APTIVUS": 2.762581063571254, "ARIXTRA": 1.2036754946225383, "ARZERRA": 1.250015618745933, "AVAMYS": 2.3028426153764805, "BELIMUMAB": 1.228606321943747, "BETAFERON": 1.2139502353165448, "BEXSERO": 2.397858542507614, "BINOCRIT": 1.3226243493614982, "BONVIVA": 1.1793460331378356, "BRIDION": 5.042629497131584, "BRILIQUE": 1.0027726761661344, "BUDESONIDE": 2.5688492003266643, "BUSILVEX": 1.1302516361773085, "CAELYX": 4.70654897127806, "CANCIDAS": 1.0480991050589676, "CAPRELSA": 1.1876102046396777, "CEFUROXIME": 2.2707003762949136, "CETUXIMAB": 1.054025157194135, "CICATRIZANTS": 12.910407378353987, "COBIMETINIB": 2.433090500088479, "CONTRAST": 3.385126887416767, "COSENTYX": 1.3450572401976812, "COTELLIC": 1.8641317957654029, "CUBICIN": 1.394789698184402, "DESLORATADINE": 1.1360523692935884, "DISPOSITIF": 14.271117903643184, "EMEND": 4.53597422504212, "ERBITUX": 1.2668952771877646, "ERLEADA": 1.189833709793042, "ESBRIET": 1.964910004582055, "EUCREAS": 1.0287929327736112, "EXFORGE": 1.2406284346942829, "FASENRA": 1.0353152795392784, "FASTURTEC": 2.8807628336855995, "FEBUXOSTAT": 1.04002849806211, "FLEBOGAMMA": 2.190214449810465, "FLUCELVAX": 2.777152689675432, "FORTIMEL": 20.47093656268918, "GAZYVARO": 1.0545681749609852, "GREPID": 3.273276644604053, "HEXYON": 2.038549033654611, "HIZENTRA": 1.1422558524661337, "HYDROCORTISONE": 2.7268610672384224, "HYQVIA": 2.997586707780755, "IDACIO": 1.804776232717913, "IMIQUIMOD": 6.580728444169679, "IMNOVID": 1.35060776829001, "INCIVO": 1.497264643962317, "INFANRIX": 1.4016286328506269, "INHIXA": 6.148474662075424, "INSUMAN": 1.1475506888856006, "IXIARO": 2.746536531545758, "KENTERA": 2.96951667317266, "KIOVIG": 2.8047878372077237, "KISQALI": 1.038206022273605, "LEMTRADA": 1.1205843599778615, "LEVOFLOXACIN": 1.973023285482972, "LUTETIUM": 1.0821072991170315, "MANNITOL": 1.957303565744117, "MENQUADFI": 3.484759199449172, "MENVEO": 5.466266583215194, "METFORMIN": 2.946051592165255, "MIDAZOLAM": 1.6855660796527254, "MIRVASO": 27.253860281990885, "MMRVAXPRO": 1.9045096912927195, "MOVYMIA": 1.4309932726662935, "NEVANAC": 1.401689071869323, "NEXAVAR": 1.7549698740663149, "NIMENRIX": 2.2121848386414182, "NIVESTIM": 4.622935345100571, "NOVONORM": 1.335087865136414, "OCRELIZUMAB": 1.306103212419924, "OLYSIO": 1.833069228316384, "OMALIZUMAB": 1.2566424102887477, "ONCASPAR": 4.785636977482769, "ONTRUZANT": 3.246179739521284, "OPTIMARK": 1.5678186474620817, "ORENCIA": 1.6673290942299033, "OSELTAMIVIR": 1.0361026793598411, "PANITUMUMAB": 1.0837304802493517, "PEGASPARGASE": 1.091606441933211, "PERJETA": 1.9971366257457897, "PERTUZUMAB": 1.685783912288238, "PIRFENIDONE": 2.533073561078234, "PLEGRIDY": 1.6123505850430224, "POTELIGEO": 1.950588280672488, "PREGABALIN": 1.4176322378566664, "PREVENAR": 2.3628016484197567, "PRIVIGEN": 1.956366025847655, "PROTELOS": 1.5075574460468844, "PROTOPIC": 4.520548656148551, "QUTENZA": 5.389011072369196, "RASILEZ": 1.1047850681048208, "REGORAFENIB": 1.264127791229768, "REKAMBYS": 1.206150516117107, "RETACRIT": 3.032512613042573, "RINVOQ": 1.034038761100676, "RIXATHON": 4.307301799748449, "ROACTEMRA": 1.6282748727454786, "SHINGRIX": 3.932258186552604, "SILGARD": 1.3971791427019078, "SKYRIZI": 1.86460324192598, "SPIKEVAX": 1.1084354562971237, "STIVARGA": 1.8104345114576792, "SUFENTANIL": 7.066948133596795, "TAFINLAR": 1.2196826896349375, "TAMIFLU": 1.2313406859016989, "TERIPARATIDE": 1.2701660409328226, "TEVAGRASTIM": 6.3232184249857255, "TOCOPHEROL": 3.337175232553817, "TORISEL": 1.0270638188975505, "TWINRIX": 1.360837742322312, "VECTIBIX": 2.259089108996288, "VEDOLIZUMAB": 1.0453092726215365, "VEKLURY": 1.2452514008085134, "VEMURAFENIB": 1.8545144258204271, "VYXEOS": 1.072906221797009, "XOLAIR": 1.750416570756235, "ZARZIO": 3.534933239769024, "ZELBORAF": 3.981335004800109, "ZYCLARA": 4.986901281586055, "ZYLLT": 4.047587861710797, "null": 1.8678736990019749}
\ No newline at end of file
+{"MYCOPHENOLATE": 118.30553058830397, "null": 4.183731851567204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2923.json
index f2775e64d83..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2923.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2923.json
@@ -1 +1 @@
-{"null": 1.4024220167936694}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2924.json
index 2f0d7eabb74..90232784971 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2924.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2924.json
@@ -1 +1 @@
-{"null": 1.656573125686241}
\ No newline at end of file
+{"AVONEX": 661.3487915994567, "null": 2.142079082935229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2925.json
index 53d6f797e43..86d96812dd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2925.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2925.json
@@ -1 +1 @@
-{"SPIKEVAX": 2.006440008413042}
\ No newline at end of file
+{"null": 6.33594583785264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2926.json
index 92896bd26a1..539b902a9c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2926.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2926.json
@@ -1 +1 @@
-{"ALDARA": 13.707163544445548, "ALIMTA": 1.4701544339361798, "BONVIVA": 1.7160044897221662, "BOSULIF": 2.351200422610988, "CELECOXIB": 1.727307515626335, "CHAMPIX": 1.2948706869886364, "CICATRIZANTS": 133.40075345068618, "COMBIVIR": 1.5378120340965038, "COTELLIC": 3.710378415420109, "DABIGATRAN": 27.12061159193146, "ERLEADA": 8.62791842080411, "EVENITY": 1.4245235763912305, "IBUPROFEN": 2.550843880225915, "IMIQUIMOD": 25.1010419806324, "INCIVO": 3.1874541747312883, "IRESSA": 1.149832335993702, "KALETRA": 1.2405390946382326, "KEYTRUDA": 4.452583286113089, "LENVIMA": 1.5426160908897142, "LEVOFLOXACIN": 2.613513015709456, "LYRICA": 1.6417879447395805, "MEKINIST": 1.6528109483586109, "MICARDIS": 2.914292761250428, "NEXAVAR": 19.887232018501354, "NIMENRIX": 1.6863123878260022, "NOT": 1.9810446882172168, "OLYSIO": 1.4069407070513924, "OPDIVO": 7.386131501351977, "OSELTAMIVIR": 6.166523403500603, "PEGASYS": 1.761176335971415, "PEGINTERFERON": 3.9199138697663782, "PEGINTRON": 3.441690826109807, "PLAVIX": 2.1051280324286297, "PREVENAR": 3.523600250929058, "PROTELOS": 7.267953419498085, "SORAFENIB": 5.510979238909851, "SOVALDI": 1.2297768325455802, "STIVARGA": 13.90676315287218, "TAGRISSO": 5.641609336630526, "TAMIFLU": 8.721989369917017, "TEMODAL": 2.1841383531529224, "TWINRIX": 1.2036033048740449, "VFEND": 1.0345537836270382, "VIRAMUNE": 3.425540464276031, "ZYCLARA": 9.560866635513914, "null": 2.479546196814607}
\ No newline at end of file
+{"null": 12.122153584666536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2927.json
index c83301cbbf7..ff7188775fd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2927.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2927.json
@@ -1 +1 @@
-{"AFINITOR": 1.149005830838297, "BOSUTINIB": 37.25654525335464, "CIMZIA": 1.3324805479142916, "COMIRNATY": 1.0394083059308126, "COSENTYX": 3.3776974736758074, "COTELLIC": 19.465977813204223, "DABRAFENIB": 15.347927069937317, "ENTYVIO": 11.648051388012092, "GARDASIL": 3.046760942743399, "GLYCOPYRRONIUM": 22.3821710176236, "KALETRA": 3.4245530662800414, "LEVOFLOXACIN": 2.1353646994259643, "LYNPARZA": 4.2322546697105485, "MEKINIST": 21.6150175839276, "PANTOPRAZOLE": 11.068155288946382, "PEGASYS": 2.434671991097386, "PEGINTRON": 1.864940741461268, "RINVOQ": 3.333841955523747, "SIMPONI": 1.1346844477061335, "STELARA": 3.3863449711733127, "TAMIFLU": 2.1780017781447123, "XOLAIR": 1.022939046103619}
\ No newline at end of file
+{"null": 6.774510232699052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2928.json
index 3213d1574a2..86468f16a5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2928.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2928.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 2.370244644901882, "MMRVAXPRO": 2.844969311147835, "SHINGRIX": 2.3120989233592377, "null": 2.135826209204301}
\ No newline at end of file
+{"null": 11.95776807702762}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2929.json
index e577a714766..ad41a5ea7b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2929.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2929.json
@@ -1 +1 @@
-{"CICLOSPORIN": 7.892118892290502, "COSENTYX": 36.56684205670264, "STELARA": 47.99823248833443, "TREMFYA": 25.11654507779735, "null": 1.0192337198319297}
\ No newline at end of file
+{"ALIMTA": 34.55065022058972, "AMIKACIN": 28.472236580355805, "AZACITIDINE": 18.07612677823669, "BUSULFAN": 13.5202056446611, "CELLCEPT": 4.804523611887899, "CICLOSPORIN": 2.893064181034062, "COMBIVIR": 11.663382328062069, "CYTARABINE": 15.742626402048776, "DOXORUBICIN": 10.595759792540417, "EMEND": 27.61739470440283, "KALETRA": 10.567118124861814, "KEPPRA": 1.42393537953962, "KEYTRUDA": 1.813177255028664, "KYMRIAH": 10.021218466821376, "MELPHALAN": 34.98050977499556, "METHOTREXATE": 3.285936336944592, "NEULASTA": 6.818391553419278, "SOLIRIS": 3.273777648808284, "TEMODAL": 35.24216535614194, "VYXEOS": 129.9025222046795, "null": 0.8224384745355793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/293.json
index 60df52e4091..95d54906558 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/293.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/293.json
@@ -1 +1 @@
-{"TOZINAMERAN": 1.5092164563352488, "null": 3.3892999561922634}
\ No newline at end of file
+{"null": 0.6110021031734242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2930.json
index 214c5456f82..e7b814382cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2930.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2930.json
@@ -1 +1 @@
-{"null": 2.837061924840992}
\ No newline at end of file
+{"ATOSIBAN": 1355.953495327631, "null": 1.0738417992000802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2931.json
index 6569b4b5bc1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2931.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2931.json
@@ -1 +1 @@
-{"ARANESP": 36.462003295443765}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2932.json
index 58f4bd89cff..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2932.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2932.json
@@ -1 +1 @@
-{"VFEND": 117.60732539112094}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2933.json
index a95a74977ae..9052cba77dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2933.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2933.json
@@ -1 +1 @@
-{"null": 2.0558291541649525}
\ No newline at end of file
+{"null": 1.8121356373762625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2934.json
index 2fa69bd8887..e1ebb7aebc5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2934.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2934.json
@@ -1 +1 @@
-{"ASPARAGINASE": 25.75877048984337, "CANCIDAS": 110.59922593877658, "null": 1.8111525539332012}
\ No newline at end of file
+{"NORVIR": 532.2562342398328, "null": 0.9994281994518696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2935.json
index bda954219fb..45253b0906e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2935.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2935.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 23.60937498931075, "BORTEZOMIB": 22.56597035148707, "CICLOSPORIN": 2.58837329841536, "CYTARABINE": 25.142345185944997, "DEXAMETHASONE": 5.557893424063658, "INCIVO": 22.441856504678576, "SOLIRIS": 7.350693579725144}
\ No newline at end of file
+{"null": 4.889954575852349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2936.json
index bf1292dd7c5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2936.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2936.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 7.273490341528614, "AMIKACIN": 11.186862530832292, "ARANESP": 1.813505076453925, "ASPARAGINASE": 7.496196773771023, "BASILIXIMAB": 23.617272533172518, "BUSULFAN": 11.530374197714682, "CELLCEPT": 6.144291053759965, "CICLOSPORIN": 8.968810489781816, "CYTARABINE": 14.761084256156671, "DEXAMETHASONE": 3.113776279073339, "ENTYVIO": 9.096285215324576, "EXJADE": 5.191075715586276, "HIZENTRA": 5.26026880475716, "HUMALOG": 1.2915611064991597, "IBRANCE": 1.4663820501707618, "IBUPROFEN": 4.692696996042766, "JARDIANCE": 5.561746740969323, "LEVOFLOXACIN": 3.311533091880843, "MEPOLIZUMAB": 2.8169032388506934, "MYCOPHENOLATE": 19.504960946915293, "PEGINTERFERON": 5.899741271473969, "SIMPONI": 1.176985166860297, "SOLIRIS": 3.5555367976179983, "SUBOXONE": 1.7502867882014126, "XELJANZ": 2.937576579340351}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2937.json
index b562f656ed7..3dc9f8eb7e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2937.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2937.json
@@ -1 +1 @@
-{"AMIKACIN": 31.99014606105109, "ASPARAGINASE": 8.326581465317668, "BUSULFAN": 16.549893273035448, "CICLOSPORIN": 2.951286134139187, "CYTARABINE": 13.254884277002946, "DEXAMETHASONE": 13.393057887307467, "JAKAVI": 7.086565715302659, "JARDIANCE": 4.673384982986748, "PEGASYS": 2.921100836387362, "PEGINTRON": 2.268377086942889, "SOLIRIS": 9.700010020606848}
\ No newline at end of file
+{"ALISKIREN": 34.60351121267122, "null": 13.081772998207786}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2938.json
index abb163b0907..f3a8b9c714b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2938.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2938.json
@@ -1 +1 @@
-{"JANUMET": 12.41131437835183, "SOLIRIS": 19.20546884435191}
\ No newline at end of file
+{"COMBIVIR": 54.60220120505437, "IBUPROFEN": 10.467357041451663, "KEPPRA": 5.14979451688972, "NEVIRAPINE": 97.95426256205126, "null": 3.8208781053982857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2939.json
index bb5a48aa17d..059e40c7aec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2939.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2939.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 15.179849052956891, "AMIKACIN": 16.734222936633564, "ARAVA": 1.6068848377882268, "CELLCEPT": 10.246265194721971, "CICLOSPORIN": 2.0282981349657483, "FORXIGA": 20.797468515968166, "JAKAVI": 4.222483264128046, "JARDIANCE": 6.069027123508414, "METHOTREXATE": 4.667647904540283, "ROACTEMRA": 4.211150812452773, "SIMPONI": 1.9498737065752256, "SOLIRIS": 12.798199854839448, "STELARA": 2.1531959699189174, "ZOSTAVAX": 3.45164344427893}
\ No newline at end of file
+{"null": 4.8401644167385305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/294.json
index fec1ff1f243..27121865cf5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/294.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/294.json
@@ -1 +1 @@
-{"null": 1.605070692234245}
\ No newline at end of file
+{"VAXZEVRIA": 4.13625847041923, "null": 1.006633644640497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2940.json
index 18ef515b287..20df2e3b843 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2940.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2940.json
@@ -1 +1 @@
-{"BYDUREON": 10.47784738645095, "BYETTA": 7.666152884303497, "ELIQUIS": 2.7015006697822392, "ENTRESTO": 3.5948513258117534, "IBRANCE": 1.287679583868785, "JANUMET": 15.538557868968844, "JANUVIA": 9.112397556056871, "LYRICA": 3.2396025555340757, "SILDENAFIL": 10.512962713762334, "TASIGNA": 7.444960695895315, "ZOSTAVAX": 71.06891966554274, "ZYPREXA": 2.396428503018617}
\ No newline at end of file
+{"null": 3.254984418596328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2941.json
index 70c547914eb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2941.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2941.json
@@ -1 +1 @@
-{"CYMBALTA": 8.91189143125125, "GARDASIL": 3.599686820589099, "null": 1.4375935123511}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2942.json
index 67a7c6271ed..3ff9ad78562 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2942.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2942.json
@@ -1 +1 @@
-{"CANAGLIFLOZIN": 78.75619550834354, "CELECOXIB": 9.017105327801564, "DAPAGLIFLOZIN": 71.7024408889011, "EMPAGLIFLOZIN": 379.8467784748874, "FORXIGA": 90.34910364123796, "INVOKANA": 51.56630694276225, "JARDIANCE": 539.4877288237964}
\ No newline at end of file
+{"COMBIVIR": 104.51399542322108, "ISENTRESS": 265.8552842613422, "null": 1.1619192809764267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2943.json
index f86a9029e22..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2943.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2943.json
@@ -1 +1 @@
-{"ABILIFY": 43.05277876806922, "ARIPIPRAZOLE": 65.51680408895152, "AZILECT": 15.180975836807365, "BRINTELLIX": 2.3286922430995203, "BUPRENORPHINE": 6.210743722049658, "CHAMPIX": 5.370952117558132, "CYMBALTA": 1.0878970453555818, "FAMPYRA": 4.0864507977874, "FENTANYL": 4.371573184279029, "FYCOMPA": 12.61722814648986, "KEPPRA": 1.7708913519076903, "LATUDA": 4.098198385265858, "LEVETIRACETAM": 2.157143875984096, "LYRICA": 5.30931359943844, "OLANZAPINE": 6.380709884814332, "POPPERS": 290.2125957149228, "SUBOXONE": 17.90177387073759, "VFEND": 1.1798782532961738, "ZYPREXA": 1.1935200774533818, "null": 2.0109994037351173}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2944.json
index 9aaf8d65487..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2944.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2944.json
@@ -1 +1 @@
-{"CYMBALTA": 4.30131504773034, "GARDASIL": 5.684287021508732, "IBUPROFEN": 18.06175415487636, "METHOTREXATE": 19.56749366796689, "TOZINAMERAN": 1.9566249651956655, "ZOSTAVAX": 22.709674856824957}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2945.json
index 33a2a2b1f34..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2945.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2945.json
@@ -1 +1 @@
-{"COVID19": 1.671611509180715}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2946.json
index a41289f557c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2946.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2946.json
@@ -1 +1 @@
-{"null": 6.406470326786169}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2947.json
index 28a0b8a6ab9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2947.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2947.json
@@ -1 +1 @@
-{"CICLOSPORIN": 18.358339012790807, "NPLATE": 88.72577118324857}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2948.json
index af21e1ac68f..9a777ce09cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2948.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2948.json
@@ -1 +1 @@
-{"ASPARAGINASE": 97.80940640266805, "FENTANYL": 24.16509020851709, "PAZOPANIB": 190.91307841316643}
\ No newline at end of file
+{"null": 3.049779723382816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2949.json
index b3d2aefa84d..3a04fb5155d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2949.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2949.json
@@ -1 +1 @@
-{"null": 1.8216547341603908}
\ No newline at end of file
+{"ELLAONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/295.json
index 6e87d9e3466..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/295.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/295.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4197320226050685, "COVID19": 1.560122154049439}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2950.json
index fc7b58a4c4d..2f5be5cf2a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2950.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2950.json
@@ -1 +1 @@
-{"MMRVAXPRO": 44.1801676623634, "null": 1.6731242729716047}
\ No newline at end of file
+{"null": 3.9788756263710106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2951.json
index 0a2ca100863..fae1295fa39 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2951.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2951.json
@@ -1 +1 @@
-{"COVID19": 1.7046889183338652, "TOZINAMERAN": 1.8673888284683773}
\ No newline at end of file
+{"ATRIPLA": 4.272644299873296, "null": 2.774573983124419}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2952.json
index c485d1249aa..9bc2c6e415a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2952.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2952.json
@@ -1 +1 @@
-{"CYMBALTA": 2.7490305975551106, "LEVETIRACETAM": 12.077227753748533, "OLANZAPINE": 8.235463546387367, "null": 1.9453618525494316}
\ No newline at end of file
+{"null": 1.481424803110106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2953.json
index 70ddbcd22de..706e2db5bae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2953.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2953.json
@@ -1 +1 @@
-{"FAMPRIDINE": 811.0982281260475, "null": 1.1569231907982669}
\ No newline at end of file
+{"null": 1.0363119880008091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2954.json
index 139a8a9b8e2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2954.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2954.json
@@ -1 +1 @@
-{"null": 3.487298748185552}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2955.json
index eff1c31094c..e664f77187d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2955.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2955.json
@@ -1 +1 @@
-{"null": 4.214356309415495}
\ No newline at end of file
+{"COMBIVIR": 51.97426602649128, "null": 2.209561131729625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2956.json
index 1e1d9ac9c21..1d8f5e29b84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2956.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2956.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 36.91344894337186, "LANTUS": 9.15645998647078, "null": 1.0118544710415287}
\ No newline at end of file
+{"APTIVUS": 5543.213819601852, "null": 1.03624784347871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2957.json
index e6d80689ab9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2957.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2957.json
@@ -1 +1 @@
-{"ADCIRCA": 4.6828264657273495, "ALISKIREN": 41.13310261376232, "ATRIPLA": 1.4807970123324528, "AVAMYS": 2.652035219518057, "BUDESONIDE": 1.31579376753483, "COMIRNATY": 3.824257425760282, "DULOXETINE": 1.950236548966109, "ENTRESTO": 3.177245322363361, "GARDASIL": 4.873134633713202, "MELATONIN": 4.117093602701224, "MEPOLIZUMAB": 1.095165358678623, "NUCALA": 2.5743509484196205, "OFEV": 1.594976787253541, "OPSUMIT": 2.0817930383592755, "PANTOPRAZOLE": 5.143940418699156, "REVATIO": 1.4671564844320633, "SILDENAFIL": 2.0939113016873887, "SPIKEVAX": 2.072699732365172, "SPIRONOLACTONE": 3.2848676507240726, "TRACLEER": 3.0743131068499108, "VALSARTAN": 4.891973175554948, "VAXZEVRIA": 1.6934116768987446}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2958.json
index f54c0f840c9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2958.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2958.json
@@ -1 +1 @@
-{"COMIRNATY": 2.276571794604867, "COVID19": 1.8576863415308007}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2959.json
index 0f9b6977e6d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2959.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2959.json
@@ -1 +1 @@
-{"CYMBALTA": 3.0694535263777505, "FYCOMPA": 17.966812824868196, "ICLUSIG": 8.586620657294072, "KEPPRA": 1.8047798456547528, "KEYTRUDA": 1.7829008292002264, "NEXAVAR": 2.618476216275731, "OPTIMARK": 27.09456818059071, "null": 1.4797527039838618}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/296.json
index 880076ac79a..a972b048617 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/296.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/296.json
@@ -1 +1 @@
-{"EMPAGLIFLOZIN": 182.72392452058568, "MEPOLIZUMAB": 85.20755279076121}
\ No newline at end of file
+{"COMIRNATY": 1.1291170790603176, "SPIKEVAX": 0.9713374331499564, "VAXZEVRIA": 1.1271225510121765, "null": 0.7760482297514499}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2960.json
index 738281c8d97..94ce7077c82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2960.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2960.json
@@ -1 +1 @@
-{"null": 1.756196526127696}
\ No newline at end of file
+{"null": 5.211177923521752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2961.json
index 0c0893875c8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2961.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2961.json
@@ -1 +1 @@
-{"APTIVUS": 901.5852294731764, "null": 3.629204653585501}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2962.json
index 266d8ee1063..511398c56a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2962.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2962.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 9.263510180266522, "CICLOSPORIN": 2.371536382911132, "COMBIVIR": 26.24100695540829, "DEXAMETHASONE": 3.1570632376240986, "KEPPRA": 3.328970420079228, "null": 1.5903084879184544}
\ No newline at end of file
+{"null": 3.3568240964189777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2963.json
index 805b3fd0f25..b4e634bfd01 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2963.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2963.json
@@ -1 +1 @@
-{"ABATACEPT": 20.170083708797023, "ADALIMUMAB": 10.687019010380975, "ARAVA": 13.483575248992612, "ATRIPLA": 1.710471025955709, "BOTULINUM": 10.2498513317249, "BYETTA": 2.0948461308653394, "CERTOLIZUMAB": 61.60156459260583, "CHOLESTAGEL": 169.81984144562443, "CIMZIA": 1.5494972726617673, "ENBREL": 2.9834508503562867, "FORSTEO": 1.068111074388186, "HUMALOG": 1.535632500881332, "HUMIRA": 2.8454322894402546, "IBRANCE": 1.329773883110123, "LANTUS": 1.1443535040359014, "LEFLUNOMIDE": 31.059253648534103, "LEVOFLOXACIN": 1.965735409072589, "LYRICA": 2.441806255464072, "SIMPONI": 3.627208068385102, "STRIBILD": 1.977521717733416, "TRUVADA": 1.8777921401791624, "VIAGRA": 2.030754037177817, "XELJANZ": 2.3880460237812327, "ZOSTAVAX": 1.627396045791043}
\ No newline at end of file
+{"null": 6.713891399299677}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2964.json
index 9042406c46b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2964.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2964.json
@@ -1 +1 @@
-{"AUBAGIO": 40.46008890025083, "BETAFERON": 263.1656190182535, "IRBESARTAN": 97.23315952462826, "LEMTRADA": 95.20882108715216, "MAVENCLAD": 723.4151365460845}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2965.json
index 35139777f69..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2965.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2965.json
@@ -1 +1 @@
-{"APIDRA": 22.927041270887827, "LANTUS": 30.08451976321808, "NOVORAPID": 49.00452325977799, "null": 2.097026550916415}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2966.json
index 384b1f4fc0a..96e7a292ba3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2966.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2966.json
@@ -1 +1 @@
-{"ABILIFY": 1.2015620267587708, "AERIUS": 4.147121098159371, "ANORO": 2.292877327935013, "APIDRA": 14.903526541911017, "DAPTOMYCIN": 34.2054777324708, "EXFORGE": 2.1088754075213507, "GLUCAGON": 29.898897788173056, "HUMALOG": 8.425817092861745, "INSULIN": 2.055255835664574, "JANUMET": 1.5695713150607788, "LANTUS": 6.527091581590771, "LEVEMIR": 4.756628150636741, "LYUMJEV": 15.131490389792624, "MMRVAXPRO": 1.3056771681502553, "NIMENRIX": 1.2112663635838743, "NOVORAPID": 3.846701851471861, "RAPAMUNE": 5.443644555469545, "RELVAR": 3.9985712147781696, "REVATIO": 7.164953475073436, "ROTATEQ": 2.38477974434178, "SAXENDA": 1.0809850887502903, "TAMIFLU": 1.31278252230642, "TOUJEO": 3.7689565369952063, "TOVIAZ": 3.0213527704479746, "TRELEGY": 1.6864401444183243, "TWINRIX": 2.4592835847579297, "VIAGRA": 4.4169697621793125, "null": 3.442835123113705}
\ No newline at end of file
+{"null": 6.138432011041116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2967.json
index 833c62b2d23..f6a457dcf79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2967.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2967.json
@@ -1 +1 @@
-{"AFINITOR": 42.05720486695459, "BONVIVA": 165.77897804957803, "SUTENT": 18.616578988131163}
\ No newline at end of file
+{"KEPPRA": 10.298883918096818, "METHOTREXATE": 10.748431680398417, "null": 6.069662125198174}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2968.json
index db9940f63b9..2c261eeb256 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2968.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2968.json
@@ -1 +1 @@
-{"ABACAVIR": 21.520575829574344, "ACTRAPID": 3.7082263932184256, "ADALIMUMAB": 4.545423019527303, "AERIUS": 2.673384896300315, "ALL": 2.3168431560993987, "ANTIBIOTICS": 4.752764445805536, "APIDRA": 3.5266191998398755, "APREMILAST": 1.4926407725579294, "APTIVUS": 5.743266026759097, "ARAVA": 1.895028666550112, "ARIXTRA": 4.472023273172317, "ATAZANAVIR": 1.447914107076979, "ATOSIBAN": 12.760720574698691, "AUBAGIO": 2.293976816732774, "AVONEX": 2.0113939867838555, "AZATHIOPRINE": 2.677519140411743, "BENLYSTA": 1.6182449444853817, "BENZODIAZEPINE": 1.417476492188622, "BIKTARVY": 1.4367493156741686, "BOSENTAN": 2.2915215939227864, "BOTULINUM": 1.0648508625154849, "BRIVARACETAM": 3.41206712951712, "BUPIVACAINE": 6.059204182388702, "BUPRENORPHINE": 3.1662705663722224, "CELSENTRI": 1.839862510294111, "CICLOSPORIN": 1.2481422879199395, "CINACALCET": 2.477879859003009, "CINRYZE": 7.8920769342315396, "COMBIVIR": 8.405629053570104, "CORTICOSTEROID": 5.354484636240363, "CYTARABINE": 1.6176793781181469, "DARUNAVIR": 8.258474821800872, "DESLORATADINE": 1.2546626746109266, "DEXAMETHASONE": 2.1565354828860306, "DEXMEDETOMIDINE": 2.8357807714388543, "DOLUTEGRAVIR": 6.658141928916503, "DULOXETINE": 1.017697920246857, "EDURANT": 3.3250774665221727, "EFAVIRENZ": 3.893067897398778, "ELLAONE": 2.68154424489079, "EMTRICITABINE": 5.70048580593172, "ENOXAPARIN": 13.161807797548445, "EPIVIR": 1.2644491883312552, "EPOETIN": 2.7412136027599825, "EVRA": 70.93397111363079, "FASENRA": 1.3135104712047507, "FENTANYL": 6.42488915295431, "FIASP": 3.109100805782613, "FONDAPARINUX": 22.15336221890334, "FYCOMPA": 2.960218242025225, "GARDASIL": 6.714412803950575, "GENERAL": 10.110248300423528, "HUMALOG": 1.6246198977508506, "HUMAN": 5.484184694915429, "HYDROCORTISONE": 3.111906826090044, "IBUPROFEN": 1.0732760846970522, "INFLIXIMAB": 1.538517877037347, "INSULATARD": 9.77326085470436, "INSULIN": 2.387463909358403, "INTELENCE": 7.613149553509169, "INTERFERON": 1.3224778433631907, "INTRONA": 1.320878028633133, "IRON": 3.869617154680877, "ISENTRESS": 10.722559134582214, "KAFTRIO": 5.294749480365308, "KALETRA": 1.9094427737410369, "KALYDECO": 3.5330318644832017, "KEPPRA": 1.8610750054036933, "KIOVIG": 4.758072862278105, "KIVEXA": 6.178409151584386, "KUVAN": 3.4241582567129507, "LACOSAMIDE": 3.5938983485307743, "LAMIVUDINE": 3.5717122455914927, "LANTUS": 1.7729634966204415, "LEMTRADA": 1.2984258711241925, "LEVEMIR": 9.110907759417248, "LEVETIRACETAM": 2.7279511649259867, "LOPINAVIR": 1.0873831542076644, "MERCAPTOPURINE": 2.5027456578084637, "MIDAZOLAM": 2.360164679340845, "MISOPROSTOL": 3.7550259546928393, "MIXTARD": 1.7802895162911752, "MMRVAXPRO": 1.3487320152806324, "NEVIRAPINE": 5.671149179341528, "NORVIR": 6.037017700391125, "NOT": 1.286709403411446, "NOVOMIX": 4.833433619030855, "NOVORAPID": 3.0728010151267915, "OLANZAPINE": 1.1348807531097864, "OSELTAMIVIR": 3.010433366954093, "PEGINTRON": 1.535042467740382, "PREZISTA": 10.666659023449665, "PRIVIGEN": 1.1606359580501713, "PROTAPHANE": 6.949151152162469, "REBETOL": 1.2790991253871833, "RELVAR": 1.3380729031917191, "REMICADE": 6.3994500945255375, "RUCONEST": 1.837807524886097, "SILDENAFIL": 1.4962667572290178, "SIMPONI": 1.4721087860318212, "SOLIRIS": 4.95084432075327, "STELARA": 6.608454595008656, "SUBOXONE": 10.919754816910489, "SUFENTANIL": 3.6708429368905486, "TACROLIMUS": 1.4733232034929953, "TAMIFLU": 1.2665863942217224, "TIVICAY": 1.430294539014504, "TOUJEO": 1.4684386799892766, "TRACTOCILE": 7.37755324372561, "TREMFYA": 2.036631118603893, "TRESIBA": 1.185823464053523, "TRIUMEQ": 2.17369320775612, "VIGABATRIN": 2.4990749426151813, "XOLAIR": 1.1897697628159445, "ZOELY": 46.89507925655583, "ZONISAMIDE": 4.932643594157653, "ZYPREXA": 1.7359681806096352, "null": 1.8555931591873425}
\ No newline at end of file
+{"null": 1.9007439671806237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2969.json
index 47ae6aa7fda..2f54d7cff94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2969.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2969.json
@@ -1 +1 @@
-{"ZOSTAVAX": 127.74748647142104}
\ No newline at end of file
+{"APTIVUS": 1569.8309245199737, "null": 2.2620104332936566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/297.json
index 1ad0469688b..07a5c58dd84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/297.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/297.json
@@ -1 +1 @@
-{"null": 3.442779540174401}
\ No newline at end of file
+{"SIMPONI": 394.6043190142624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2970.json
index 6a31422ced5..1d979d302bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2970.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2970.json
@@ -1 +1 @@
-{"CIMZIA": 6.634374531411826, "MEPOLIZUMAB": 46.01003521532816, "SPIKEVAX": 4.5752358474877886, "TOZINAMERAN": 5.366184087862226, "XELJANZ": 3.7078327251033394}
\ No newline at end of file
+{"null": 3.015891500848607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2971.json
index 91ed2434b50..adb2c9e8d6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2971.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2971.json
@@ -1 +1 @@
-{"OMALIZUMAB": 134.88905424791486}
\ No newline at end of file
+{"null": 5.839365350190303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2972.json
index 584513b905a..b49973be1eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2972.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2972.json
@@ -1 +1 @@
-{"null": 1.986892532105631}
\ No newline at end of file
+{"null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2973.json
index 8a72b0ed7d5..7dab0060542 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2973.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2973.json
@@ -1 +1 @@
-{"null": 2.387043285011238}
\ No newline at end of file
+{"SOMATROPIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2974.json
index 48d13ce8bee..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2974.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2974.json
@@ -1 +1 @@
-{"null": 1.486439739549122}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2975.json
index c5296150b59..cc8d8653113 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2975.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2975.json
@@ -1 +1 @@
-{"null": 3.036245348071156}
\ No newline at end of file
+{"null": 10.212975161500392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2976.json
index c82dd5e0279..90cfb509b77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2976.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2976.json
@@ -1 +1 @@
-{"null": 4.802594096429057}
\ No newline at end of file
+{"KALETRA": 83.80018417855474, "null": 2.0900336058639093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2977.json
index a9fcdc81cab..3134c5e1810 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2977.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2977.json
@@ -1 +1 @@
-{"BARACLUDE": 202.87908817627135, "PEGASYS": 2.433652797289394, "PEGINTRON": 27.624750342598524, "null": 1.837962632862841}
\ No newline at end of file
+{"null": 6.910430732697807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2978.json
index 937ffa1ef2f..26b792e3afe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2978.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2978.json
@@ -1 +1 @@
-{"ABILIFY": 3.311328262070821, "APIDRA": 4.679806767191686, "BUPIVACAINE": 11.285164732104995, "BUPRENORPHINE": 39.10463075996768, "BUVIDAL": 41.70322730908055, "CIMZIA": 5.601344619762495, "COMIRNATY": 1.0420014667417663, "ELLAONE": 6.543293460583357, "ENOXAPARIN": 9.158705543895335, "HUMALOG": 2.807930018753666, "KEPPRA": 4.812187527077993, "LANTUS": 1.1818884978599726, "LATUDA": 1.6386034941865268, "LEVEMIR": 3.895024508278608, "LEVETIRACETAM": 1.6035411417976884, "MELATONIN": 4.427784604890537, "MIDAZOLAM": 2.1679364316044296, "OPIATES": 155.96923786553293, "OPIOIDS": 51.87075023362419, "SOLIRIS": 2.737814209660672, "STELARA": 1.5399124238106183, "SUBOXONE": 54.04176509899519, "TOZINAMERAN": 1.8925535576202583, "ZYPREXA": 1.6737919223148203}
\ No newline at end of file
+{"NOVORAPID": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2979.json
index 96ef5fa6680..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2979.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2979.json
@@ -1 +1 @@
-{"null": 4.385314579180378}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/298.json
index 4f6c8c0b334..2e393b69814 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/298.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/298.json
@@ -1 +1 @@
-{"PRIVIGEN": 272.9148648519022, "null": 1.214010444928523}
\ No newline at end of file
+{"COMIRNATY": 1.7397712976544613, "null": 0.966937321188353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2980.json
index b8018184ef9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2980.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2980.json
@@ -1 +1 @@
-{"null": 4.397641702896371}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2981.json
index d872febe280..9fbbc8f4b40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2981.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2981.json
@@ -1 +1 @@
-{"null": 2.6974128087585774}
\ No newline at end of file
+{"null": 1.7094405736763596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2982.json
index abf5c280186..2c261eeb256 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2982.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2982.json
@@ -1 +1 @@
-{"COSENTYX": 33.01741294795728, "VIAGRA": 32.05030219137888}
\ No newline at end of file
+{"null": 1.9007439671806237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2983.json
index c8feedf51e0..0e9c5c4ec69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2983.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2983.json
@@ -1 +1 @@
-{"BENLYSTA": 92.24110670668782, "MMRVAXPRO": 5.141620923760652, "NUCALA": 69.02797586140414, "PEGASYS": 2.6800920082488298, "ROACTEMRA": 13.95104498284655, "SIMPONI": 8.904465749708338, "null": 1.0038675760767424}
\ No newline at end of file
+{"COMBIVIR": 97.75788308783716, "null": 2.840204206684529}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2984.json
index c92fc0c8731..69f26968d46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2984.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2984.json
@@ -1 +1 @@
-{"null": 10.338195159448963}
\ No newline at end of file
+{"COMBIVIR": 91.38563586304085, "null": 2.1516996988658548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2985.json
index 5c9cfe0182e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2985.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2985.json
@@ -1 +1 @@
-{"NOVOSEVEN": 960.9056807734388}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2986.json
index 7b1d92cb415..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2986.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2986.json
@@ -1 +1 @@
-{"COMIRNATY": 3.87458736113978, "COVID19": 1.2193191183096257, "MENVEO": 15.1349492679496, "MMRVAXPRO": 2.941809985853985, "NIMENRIX": 5.430038249084654, "SHINGRIX": 2.789259949399849, "SPIKEVAX": 11.76699274190488, "TWINRIX": 1.6015864549640146, "VAXZEVRIA": 1.9565143539006324}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2987.json
index be8131f2c48..8c32c8974de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2987.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2987.json
@@ -1 +1 @@
-{"CICLOSPORIN": 4.021691350866382, "FENTANYL": 3.9304131438209375, "MIDAZOLAM": 28.5798163757589, "null": 3.22318629535282}
\ No newline at end of file
+{"null": 5.919970690522823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2988.json
index eb5de80ec54..52ecae3991f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2988.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2988.json
@@ -1 +1 @@
-{"CELLCEPT": 97.15114321342358}
\ No newline at end of file
+{"null": 4.742344713118714}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2989.json
index db2dcae05f9..89e0c1eb07d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2989.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2989.json
@@ -1 +1 @@
-{"null": 1.7699517587271436}
\ No newline at end of file
+{"null": 1.4003020621202162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/299.json
index 3fc96e9dd5a..30380b6ee3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/299.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/299.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 64.30802692677703, "SUFENTANIL": 186.1501833360041, "null": 3.9689408540697295}
\ No newline at end of file
+{"null": 1.719128601799418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2990.json
index a5c024d0fc1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2990.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2990.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3424329281989724, "COVID19": 1.858478370006707}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2991.json
index cfc0bdc28bc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2991.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2991.json
@@ -1 +1 @@
-{"ACTRAPID": 8.751528734546733, "ADVATE": 46.93094278082483, "APIDRA": 7.200250256029633, "APIXABAN": 1.116233649280037, "AUBAGIO": 1.1757321115697708, "BRIDION": 7.008260246426186, "BUPIVACAINE": 18.115234446117157, "BYETTA": 1.498202594204081, "ELIQUIS": 1.306818093375346, "FAMPYRA": 3.8930002781424022, "FIASP": 13.381476451202452, "GARDASIL": 1.532940116482454, "HUMALOG": 3.215002925208073, "INSULIN": 5.332506304324538, "IRBESARTAN": 3.3056372428490173, "KEPPRA": 1.7691594794846783, "LANTUS": 3.702008819154552, "LATUDA": 2.005714666111704, "LEVEMIR": 3.581489010946356, "MEPOLIZUMAB": 2.6112144004334747, "MMRVAXPRO": 1.2224094384517716, "NOVORAPID": 11.69138153834254, "OPSUMIT": 1.8500867727901744, "PLAVIX": 1.131022156545335, "RELVAR": 4.5492002493578765, "ROTATEQ": 1.962784754446847, "SHINGRIX": 5.62001279064319, "SOLIRIS": 1.014710141184798, "SUBOXONE": 3.010074914349392, "TOUJEO": 8.135734389530755, "TOVIAZ": 2.127016158423624, "TOZINAMERAN": 1.046570562623084, "TRELEGY": 8.902964480715895, "TRESIBA": 13.95824173359262, "TRULICITY": 7.982154545373312, "TWINRIX": 6.067105121553268, "VIAGRA": 6.469810207809299, "VICTOZA": 1.8006826003686422, "ZOSTAVAX": 8.200312703226981, "null": 1.8048306821072488}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2992.json
index 9d7bce9fb4c..b9bf5e3e8fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2992.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2992.json
@@ -1 +1 @@
-{"CUBICIN": 43.56351430047237, "FENTANYL": 29.339257030381468, "null": 1.2657926108850814}
\ No newline at end of file
+{"null": 4.957218999046537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2993.json
index adee9c4fb9c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2993.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2993.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 26.784113594487632, "ELIQUIS": 13.029187238033831, "ENOXAPARIN": 44.1142452918582, "FENTANYL": 3.016220632478895, "PLAVIX": 14.325601460742062, "null": 2.0117790350714846}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2994.json
index f21c804c463..bdd04befef1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2994.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2994.json
@@ -1 +1 @@
-{"JAKAVI": 67.64561622615646, "REBLOZYL": 2219.0164051742645}
\ No newline at end of file
+{"null": 2.94987525317943}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2995.json
index cbc1be1a60d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2995.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2995.json
@@ -1 +1 @@
-{"CICLOSPORIN": 13.908532496924847}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2996.json
index 2901d6c42ba..3a9d0cf08cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2996.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2996.json
@@ -1 +1 @@
-{"ABILIFY": 16.605309826226417, "AGOMELATINE": 34.82692629723762, "AIMOVIG": 9.769733496966031, "ARIPIPRAZOLE": 49.71137312490698, "BRINTELLIX": 1.7718711828823197, "CARIPRAZINE": 39.464137526062856, "CORTICOSTEROIDS": 17.00860541866718, "CYMBALTA": 1.7125555117303692, "DULOXETINE": 1.752161045612659, "EBIXA": 9.32988702400309, "ERENUMAB": 60.99521700526485, "INVEGA": 30.399788263878825, "IRBESARTAN": 2.114318540252831, "KEPPRA": 1.1488648993841104, "LATUDA": 16.212708043419088, "LEVETIRACETAM": 1.7376252801152938, "LEVODOPA": 4.9289084823178575, "LOXAPINE": 17.46911214507023, "LURASIDONE": 11.732415876037631, "LYRICA": 1.3547804514776178, "OLANZAPINE": 31.59042515538941, "PALIPERIDONE": 34.98160331614806, "PREGABALIN": 1.409944510493213, "REAGILA": 27.447262021474742, "RISPERIDONE": 35.78011921299647, "SYCREST": 65.71557977440469, "VIMPAT": 1.2893505419592115, "XEPLION": 53.19828458071488, "ZYPADHERA": 24.678070147681662, "ZYPREXA": 17.223853266768288, "null": 2.5703932687781457}
\ No newline at end of file
+{"null": 2.118328606160788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2997.json
index 1e2b3ca4d8b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2997.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2997.json
@@ -1 +1 @@
-{"null": 1.2763921387255468}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2998.json
index 22769ae6536..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2998.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2998.json
@@ -1 +1 @@
-{"AIMOVIG": 1.0865813576362124, "COMIRNATY": 2.657279370850107, "ENTRESTO": 1.5099622174027467, "EXFORGE": 1.593036520777595, "FORSTEO": 1.4286716592497912, "ICLUSIG": 1.6455544643079365, "IRBESARTAN": 6.926790779835981, "MIDAZOLAM": 2.38297051537289, "MULTAQ": 6.433265702433401, "OXYBUTYNIN": 4.195771481550629, "RASILEZ": 6.111300369107672, "SPIKEVAX": 1.7927628759641854, "TASIGNA": 1.2125798494574689, "TOZINAMERAN": 1.620961803193495, "VFEND": 1.0182986179561964}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2999.json
index a23e85d33db..9ed96e3a06b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2999.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/2999.json
@@ -1 +1 @@
-{"BONVIVA": 16.3326894785501, "CAELYX": 24.702306206251336, "DARZALEX": 19.75494220537353, "DEXDOR": 90.8609320988482, "ENTRESTO": 1.6155217084271318, "FENTANYL": 3.6286833879492537, "JEVTANA": 22.20810187434947, "KEPPRA": 1.402477641212865, "KYPROLIS": 23.3146038766316, "NAGLAZYME": 11.603848051508804, "PRIVIGEN": 12.787199123165037, "REMDESIVIR": 32.38295497765729, "TORISEL": 12.820160625412464, "TRODELVY": 14.92973406017034, "YONDELIS": 219.13372806767552, "null": 4.223151899885759}
\ No newline at end of file
+{"SUBOXONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3.json
index ba2613ad196..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3.json
@@ -1 +1 @@
-{"null": 1.2229875075149683}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/30.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/30.json
index 9f940e22e80..262faf3fc63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/30.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/30.json
@@ -1 +1 @@
-{"COVID19": 1.114497575047391, "null": 1.158629917492077}
\ No newline at end of file
+{"CASPOFUNGIN": 73.40130016887204, "COMIRNATY": 0.0797530041441602, "CYTARABINE": 10.285658777435517, "LANTUS": 2.800649591573717, "PEGASYS": 2.394671059154865, "SUTENT": 3.762050249305125, "null": 0.6466547707928143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/300.json
index 16f86df28ed..ce65657c946 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/300.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/300.json
@@ -1 +1 @@
-{"null": 9.463109291441148}
\ No newline at end of file
+{"null": 7.527792121775279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3000.json
index 77350fa3b7f..d7e80e1d246 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3000.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3000.json
@@ -1 +1 @@
-{"BRILIQUE": 44.204051593416416, "CLOPIDOGREL": 7.332865957705076}
\ No newline at end of file
+{"null": 2.787377073635478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3001.json
index fbeadebc335..52f5f123f57 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3001.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3001.json
@@ -1 +1 @@
-{"SOLIRIS": 1919.7828075689256}
\ No newline at end of file
+{"null": 4.851704902156779}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3002.json
index 04e9ab9345e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3002.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3002.json
@@ -1 +1 @@
-{"ARAVA": 4.12261672161392, "CONTRAST": 410.1498784139749, "OPTIMARK": 393.88532200964505}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3003.json
index 283a142ac9a..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3003.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3003.json
@@ -1 +1 @@
-{"ELIQUIS": 1.3083986376628578, "FORXIGA": 8.039995467351243, "JARDIANCE": 10.071552464857172, "LANTUS": 2.7367277827813163, "NEXAVAR": 2.910304177394224, "PEGASYS": 1.9737074722451704, "ROACTEMRA": 18.15925739244891, "null": 1.123396521021089}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3004.json
index d581be40e06..23d59bea006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3004.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3004.json
@@ -1 +1 @@
-{"null": 1.1821588320254246}
\ No newline at end of file
+{"ISENTRESS": 373.43530172302894, "null": 4.573959819994757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3005.json
index 2d7a553940d..8ac3105c02c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3005.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3005.json
@@ -1 +1 @@
-{"COVID19": 1.2365884422595623, "TOZINAMERAN": 1.5746574348464366, "null": 1.15128318339953}
\ No newline at end of file
+{"null": 4.3593139447282905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3006.json
index cd6872287f5..1197b82fdb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3006.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3006.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.045354321436582, "SUTENT": 5.289412305891497}
\ No newline at end of file
+{"null": 3.074243099940253}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3007.json
index 8baebee2bc7..fa957607e8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3007.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3007.json
@@ -1 +1 @@
-{"null": 2.1487608395327937}
\ No newline at end of file
+{"APTIVUS": 547.0517563409115, "IBUPROFEN": 13.645697509034193, "KEPPRA": 3.94923095786999, "null": 3.0767058849160183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3008.json
index 0c21ba23826..ba749eecdea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3008.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3008.json
@@ -1 +1 @@
-{"CYMBALTA": 1.4892374366446983, "ELIQUIS": 3.0756714839623074, "LYRICA": 10.759858698931872, "OMALIZUMAB": 5.905642435805313, "SUTENT": 1.294655053641632, "TOZINAMERAN": 1.9349258519034944, "null": 1.0248974127801287}
\ No newline at end of file
+{"KEPPRA": 6.049093464150563, "null": 7.179829191083127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3009.json
index e0ebfd976fb..8d153d126ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3009.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3009.json
@@ -1 +1 @@
-{"null": 2.387467590390321}
\ No newline at end of file
+{"DARUNAVIR": 103.0228886161948, "null": 5.486342904786169}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/301.json
index 73cab0727ff..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/301.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/301.json
@@ -1 +1 @@
-{"ABILIFY": 7.597548083916496, "GARDASIL": 5.06044881761342, "IBUPROFEN": 9.204938023619995, "OMALIZUMAB": 59.334493209915, "PANTOPRAZOLE": 47.73836835976505, "UMECLIDINIUM": 166.09993044314527, "XOLAIR": 5.336252706063613}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3010.json
index 6dc4167f94b..532be09af92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3010.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3010.json
@@ -1 +1 @@
-{"AFINITOR": 1.3914282653005732, "COSENTYX": 2.450177049765646, "EYLEA": 13.289215087438189, "HUMALOG": 1.1100523589397473, "IBRANCE": 1.1620654844643004, "MMRVAXPRO": 2.7405085538727927, "NEVANAC": 123.80653717525392, "OMALIZUMAB": 7.523068777922456, "PEGASYS": 1.827102613954753, "SUTENT": 1.3202149408145587, "XELJANZ": 1.8523181619517857, "ZOSTAVAX": 2.14234490059549, "null": 1.860738132832825}
\ No newline at end of file
+{"APTIVUS": 1140.4637512091592, "null": 3.1593372525361616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3011.json
index 4a9381fc346..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3011.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3011.json
@@ -1 +1 @@
-{"ANORO": 3.447924216052355, "APIDRA": 2.0224992256868477, "ARAVA": 1.1820695159042025, "AUBAGIO": 1.1594906871676578, "AVANDAMET": 1.567732828958265, "AVANDIA": 1.444272667426462, "BOSULIF": 1.5247744650969517, "BRAFTOVI": 4.897555542825799, "BYDUREON": 1.19789043745065, "CELECOXIB": 1.941833926438282, "CIMZIA": 1.0415501926909854, "CYMBALTA": 1.178060723060577, "DEXAMETHASONE": 1.3818496708949557, "DUPIXENT": 4.414523749454035, "ELIQUIS": 2.486244237740256, "ENBREL": 2.873255550392474, "EVISTA": 1.5019990486204122, "EXFORGE": 1.6063358271470696, "EXJADE": 1.5174370304223226, "EYLEA": 9.147191615736746, "FASENRA": 2.434512807499739, "FORSTEO": 1.0008795775082318, "GARDASIL": 1.0497610806799158, "HUMALOG": 5.44849776292134, "HUMIRA": 2.6357066813848906, "IBRANCE": 1.883563234821788, "IBUPROFEN": 1.0413682136310718, "INLYTA": 1.481120414208157, "INSULIN": 1.6668128091092187, "JANUVIA": 1.0602309788384303, "LANTUS": 7.314288880185126, "LEVEMIR": 1.8301716223844824, "LYRICA": 1.4143202750400368, "MEKINIST": 2.170084256193644, "NORVIR": 2.056079777300712, "OMALIZUMAB": 1.3203562114263294, "PEGASYS": 1.0377379763768049, "PEGINTRON": 1.410096193364868, "REVATIO": 2.9090227193725964, "RINVOQ": 1.6525972360797772, "RITUXIMAB": 1.5434449320330017, "SIMPONI": 1.105709435921169, "TAGRISSO": 1.4031172844899693, "TOUJEO": 2.5231741222247206, "TOVIAZ": 3.862410515655502, "TOZINAMERAN": 1.2748663476566298, "TRELEGY": 1.577873612511274, "TRULICITY": 1.1176445199604526, "VFEND": 1.5807457858995733, "VIAGRA": 4.273283090443046, "VORICONAZOLE": 3.290277163194757, "XALKORI": 1.8772777277856096, "XELJANZ": 2.0845262123786106, "XOLAIR": 1.129096824945211, "ZOSTAVAX": 2.5532981991579757, "null": 1.4240113334142812}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3012.json
index 38f14ad413d..0aed3a55351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3012.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3012.json
@@ -1 +1 @@
-{"COMIRNATY": 2.272357017338263, "COVID19": 1.0413009258102512, "ELIQUIS": 4.417189613743751, "VAXZEVRIA": 3.9791338003504406}
\ No newline at end of file
+{"null": 0.9309637469000248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3013.json
index 981b5c86b3b..921117290c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3013.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3013.json
@@ -1 +1 @@
-{"APIDRA": 4.1376915037159385, "AVASTIN": 1.406055777128948, "BEOVU": 9.11409884699867, "BRILIQUE": 6.047507105227237, "CLOPIDOGREL": 2.7575271147324703, "ELIQUIS": 11.313018125307648, "ESOMEPRAZOLE": 2.770930800760256, "EVISTA": 2.109717247523056, "EXFORGE": 1.6513093768592926, "EYLEA": 32.4093703467766, "HUMALOG": 17.461212754937904, "INSULIN": 3.907672788597859, "ISCOVER": 10.8854025500992, "LANTUS": 8.69388154588961, "LEVEMIR": 3.070288391555473, "LIXIANA": 11.539768936071326, "MAYZENT": 77.41697412515178, "NEVANAC": 6.632189376763898, "PEGASYS": 1.2143532333552318, "PLAVIX": 9.721068054294289, "REVATIO": 1.801388669231104, "SILDENAFIL": 3.340113090596747, "SPRYCEL": 2.001490514118895, "SUTENT": 1.255125788781952, "TICAGRELOR": 2.471622456330378, "TOUJEO": 3.167798709297984, "TOVIAZ": 1.4622829554931742, "TRELEGY": 3.280575214961225, "TRULICITY": 1.9250460646652048, "VIAGRA": 4.327113849497902, "VICTOZA": 1.2230699410800716, "XARELTO": 2.640729038651833, "XYREM": 3.0555226287267105}
\ No newline at end of file
+{"null": 6.661033395547756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3014.json
index 55cc0baeb86..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3014.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3014.json
@@ -1 +1 @@
-{"COMIRNATY": 4.901815099408192, "SPIKEVAX": 2.621690883762172, "VAXZEVRIA": 2.495316970181389}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3015.json
index 43a586dfd87..6ef930af512 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3015.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3015.json
@@ -1 +1 @@
-{"ARAVA": 1.177594813537549, "BENLYSTA": 4.737690334207903, "CIMZIA": 2.0051793342526394, "COSENTYX": 3.0420848318206075, "DUPIXENT": 54.53690993932045, "EYLEA": 39.06543684664333, "FORSTEO": 1.3109076054755375, "HIZENTRA": 5.559984873022812, "HUMALOG": 1.138304214030557, "HUMIRA": 2.686660698082731, "IBRANCE": 1.1916411887373235, "LANTUS": 2.512431737706121, "REVATIO": 6.816912119640038, "RITUXIMAB": 4.709715159127006, "SIMPONI": 7.017748078676494, "XELJANZ": 7.880904154230506, "ZOSTAVAX": 4.799395420799756}
\ No newline at end of file
+{"null": 7.156022983130646}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3016.json
index 0cf4f5c96d3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3016.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3016.json
@@ -1 +1 @@
-{"EYLEA": 129.1118201597616}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3017.json
index c05dec23dee..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3017.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3017.json
@@ -1 +1 @@
-{"ANIDULAFUNGIN": 1305.0195962222592}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3018.json
index e38ad75b760..8e8853d3896 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3018.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3018.json
@@ -1 +1 @@
-{"EYLEA": 87.94672136434488, "null": 7.614347480759988}
\ No newline at end of file
+{"null": 8.969869482806406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3019.json
index 6991c727ac2..6c228274a9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3019.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3019.json
@@ -1 +1 @@
-{"EYLEA": 454.60348197958166}
\ No newline at end of file
+{"null": 9.52304895520586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/302.json
index fcfd2b1d1af..c6ba13206c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/302.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/302.json
@@ -1 +1 @@
-{"COMIRNATY": 1.706712012531547, "TOZINAMERAN": 2.3827473865841333}
\ No newline at end of file
+{"BETMIGA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3020.json
index c563fac0a87..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3020.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3020.json
@@ -1 +1 @@
-{"AVASTIN": 2.4011158012173035, "BEOVU": 327.8943497620763, "BROLUCIZUMAB": 266.51048458961844, "CICLOSPORIN": 1.12178493611253, "COSENTYX": 1.6557507989637466, "ENTYVIO": 1.453266906962135, "EYLEA": 254.6131071060545, "MMRVAXPRO": 5.861368482614195, "NEVANAC": 19.05092008840178, "SHINGRIX": 1.443414364005507, "SIMPONI": 1.0248390634928164}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3021.json
index 6d9fa1d5f0b..5db20dc5145 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3021.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3021.json
@@ -1 +1 @@
-{"ADALIMUMAB": 24.461604664205257, "AVANDIA": 1.8747662521689687, "BEOVU": 21.658271422350285, "CLOPIDOGREL": 1.7388603847251445, "ENBREL": 1.7964950268264974, "EYLEA": 8.227117728212026, "HUMALOG": 3.809969923747053, "HUMIRA": 10.811378478596708, "KEPPRA": 1.2607643846139518, "LANTUS": 2.0590117073730747, "NEVANAC": 44.86974810301137, "TOZINAMERAN": 2.3620631618509718, "ZOSTAVAX": 2.8774390464823547}
\ No newline at end of file
+{"null": 2.846137987720282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3022.json
index bd8e1a2423e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3022.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3022.json
@@ -1 +1 @@
-{"ANORO": 1.6445000892874362, "AZOPT": 11.497342259300076, "BEOVU": 15.833640763139837, "BRIMONIDINE": 67.0115553044586, "CHLORHEXIDINE": 1.8508318569471096, "ENTYVIO": 1.2930991398057394, "EYLEA": 10.467813731777854, "IKERVIS": 324.3741309271525, "LIXIANA": 1.455601730775199, "LUCENTIS": 27.923730388082124, "MEPOLIZUMAB": 2.1540413066700155, "NEVANAC": 69.30522951896134, "OPATANOL": 91.33153698774557, "PEGASYS": 1.0928393686859446, "PEGINTERFERON": 1.4037246746043497, "QUTENZA": 24.07825256900238, "SHINGRIX": 1.2003539392259337, "TOZINAMERAN": 1.1000539133833045, "TRELEGY": 1.1155010026747396, "VIAGRA": 1.3108774173268734, "ZOSTAVAX": 1.1787021885900826, "null": 1.974373547692143}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3023.json
index 0eba52d1b49..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3023.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3023.json
@@ -1 +1 @@
-{"HUMALOG": 12.728311454621153, "LANTUS": 19.88466026274985, "null": 1.1890343634009342}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3024.json
index 6e71d7a0433..875afcd9d79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3024.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3024.json
@@ -1 +1 @@
-{"null": 1.4295803886415972}
\ No newline at end of file
+{"null": 6.419376377439372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3025.json
index d79a213ec96..fa63acb3950 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3025.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3025.json
@@ -1 +1 @@
-{"ABILIFY": 1.1261841183837726, "ARIPIPRAZOLE": 1.0959651955954557, "AUBAGIO": 1.9796027170449533, "BEXSERO": 10.199011013669768, "CICLOSPORIN": 1.1628443282286702, "FIRDAPSE": 5.286820300412947, "GARDASIL": 10.217407710713417, "INFANRIX": 17.36099878463675, "INSULIN": 1.288874249164347, "KEPPRA": 1.2491289592352754, "LACOSAMIDE": 4.374897332151165, "LATUDA": 2.780552109262024, "LEVETIRACETAM": 1.635903489131875, "MENVEO": 10.952024416446344, "MMRVAXPRO": 3.96700055365045, "NIMENRIX": 6.689054600506044, "OLANZAPINE": 2.072099087014061, "PREVENAR": 6.301527756001803, "ROTATEQ": 3.0815105586530165, "SODIUM": 46.17764180242136, "TAMIFLU": 2.1886468204294136, "TOZINAMERAN": 1.1289750378854968, "ZYPREXA": 2.5836841658192555, "null": 2.128595587028045}
\ No newline at end of file
+{"null": 1.3183814393892817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3026.json
index 7ca43731d96..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3026.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3026.json
@@ -1 +1 @@
-{"BEOVU": 17.22268823265324, "CHAMPIX": 1.0581254128237534, "ENTRESTO": 1.6101584302951215, "EYLEA": 13.80709139753885, "SUTENT": 1.5110977882909646, "XOLAIR": 3.103130538697072, "null": 2.215526669831582}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3027.json
index 9917e2772f1..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3027.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3027.json
@@ -1 +1 @@
-{"ELIQUIS": 1.65395530928084, "ENBREL": 5.346340697528044, "EYLEA": 8.098176816648339, "HUMALOG": 2.9594184603574747, "IBRANCE": 6.490944616717565, "JANUMET": 8.146558387597219, "JARDIANCE": 2.217988834485067, "LANTUS": 18.48101624800588, "LEVEMIR": 5.94635035443528, "OPSUMIT": 2.9027119802160875, "SIMPONI": 7.688583849117959, "STELARA": 2.238253465977187, "VELTASSA": 25.131552688500403, "XELJANZ": 4.1889883301279385, "ZOSTAVAX": 2.331425337200373, "null": 1.3078898791678817}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3028.json
index 7a948570b9c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3028.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3028.json
@@ -1 +1 @@
-{"AIMOVIG": 1.092724203820013, "ALDARA": 1.6843322828019125, "AZILECT": 5.332908202461363, "AZOPT": 8.844785519530927, "BAQSIMI": 11.729345344384743, "BELIMUMAB": 1.8964228116152468, "BEOVU": 25.685321557989138, "BRIMONIDINE": 12.531858574035065, "BRINTELLIX": 1.2302434544386125, "BROLUCIZUMAB": 35.02150537037874, "CHAMPIX": 1.3004537172366235, "COMIRNATY": 1.286404169368169, "COVID19": 3.7386778630514574, "DUPIXENT": 4.082846102819229, "ERENUMAB": 2.568265196173149, "EYLEA": 28.59637096345653, "GARDASIL": 1.290570400709379, "HYDROCHLOROTHIAZIDE": 4.479097198272771, "IKERVIS": 72.48049292124732, "INCRUSE": 2.534808443364394, "INTELENCE": 2.7160391488955344, "JETREA": 15.376187844445644, "LUCENTIS": 17.82701144203305, "MAVENCLAD": 1.4060809087252673, "MYCOPHENOLATE": 1.210191481412729, "NEPAFENAC": 23.506506338721024, "NEVANAC": 17.243385244591956, "NIMENRIX": 1.3017603402077809, "OPATANOL": 21.302859423327806, "PREGABALIN": 1.4107606028243662, "QUTENZA": 4.123300743251277, "SHINGRIX": 1.227123355649824, "SPIKEVAX": 1.1437723331923804, "TELMISARTAN": 1.6367263982292557, "TOBRAMYCIN": 3.4165936959212977, "TOZINAMERAN": 2.549512337552072, "TRELEGY": 1.1270290825227176, "VAXZEVRIA": 2.3517328425613084, "VIAGRA": 1.121961660430734, "ZOSTAVAX": 1.073363862444219}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3029.json
index d23e0acb055..48198e5d56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3029.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3029.json
@@ -1 +1 @@
-{"COMIRNATY": 2.512606360107472, "NUCALA": 34.26641955359657}
\ No newline at end of file
+{"null": 0.9986656045005448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/303.json
index 01e6ed56ea0..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/303.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/303.json
@@ -1 +1 @@
-{"COMIRNATY": 2.0804350432753664}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3030.json
index fd9a850df7f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3030.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3030.json
@@ -1 +1 @@
-{"AIMOVIG": 1.1393351444361, "APIXABAN": 22.50893823645626, "AVAMYS": 3.407650325512399, "BUDESONIDE": 13.3830850288487, "CARBIDOPA": 19.940761568079747, "EYLEA": 1.3720241013708043, "FASENRA": 1.2778536944010357, "FLUTICASONE": 33.895582284287684, "IKERVIS": 51.54901934553404, "MEPOLIZUMAB": 8.67638608415968, "MMRVAXPRO": 1.0328595437531964, "NEVANAC": 9.125705316705805, "NUCALA": 16.47889463962502, "OMALIZUMAB": 2.484991595782415, "OPATANOL": 79.82687449024846, "PANTOPRAZOLE": 3.074106916928772, "QUTENZA": 4.7326865192753935, "RELVAR": 1.944693250926992, "RITUXIMAB": 1.6426909114351522, "TOZINAMERAN": 1.6617702886461023, "XOLAIR": 4.486953457092273, "ZOSTAVAX": 1.0281908857479074, "null": 1.3952697851114406}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3031.json
index 23753c65cd7..0bdffd30da3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3031.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3031.json
@@ -1 +1 @@
-{"AERIUS": 1.4234316944357437, "BETMIGA": 3.440645511527012, "BOSULIF": 1.242269307226885, "COVID19": 1.185273933775573, "DELAMANID": 2.412843267848349, "ENTRESTO": 1.016068785537482, "EXFORGE": 1.8060976558845525, "EYLEA": 3.959579593691514, "GARDASIL": 1.3130896097401217, "HIZENTRA": 1.2655629851138313, "HYDROCORTISONE": 2.527822239397661, "IKERVIS": 16.442496623357297, "IRBESARTAN": 1.0157569520908245, "MMRVAXPRO": 1.34892307559695, "NEVANAC": 9.686785587428348, "NIMENRIX": 1.3156052563691825, "NUCALA": 4.59107640911883, "OMALIZUMAB": 2.5478540952952824, "OPATANOL": 22.69356933040864, "PEGASYS": 1.3129412125358102, "RASILEZ": 1.3207862192428377, "RINVOQ": 1.334749823201464, "SHINGRIX": 1.2765149346375722, "SPRYCEL": 1.2873444082940075, "SUTENT": 2.502442721798147, "TAMIFLU": 1.1054504871827124, "TOBRAMYCIN": 3.379485528471644, "TOZINAMERAN": 2.7993018908731995, "TWINRIX": 1.4416614419850546, "XOLAIR": 2.607784550082871, "null": 1.5894028828176614}
\ No newline at end of file
+{"null": 10.126025606041642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3032.json
index 8510d39adc4..8489f63cf5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3032.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3032.json
@@ -1 +1 @@
-{"BRAFTOVI": 50.00329232035875}
\ No newline at end of file
+{"null": 7.592128051040705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3033.json
index 2544d169cdc..3dc7db822b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3033.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3033.json
@@ -1 +1 @@
-{"SUTENT": 44.67562738771224, "VOTRIENT": 56.772157237581325}
\ No newline at end of file
+{"null": 6.853633475399323}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3034.json
index 1e0e326446a..7d59cbd8a9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3034.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3034.json
@@ -1 +1 @@
-{"VAXZEVRIA": 2.84660536404007}
\ No newline at end of file
+{"null": 3.876165964643629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3035.json
index f77df72163c..e36ac4c095e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3035.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3035.json
@@ -1 +1 @@
-{"COVID19": 2.840982603901688}
\ No newline at end of file
+{"null": 0.9814585982551852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3036.json
index b2cf22ce680..b8a2491a508 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3036.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3036.json
@@ -1 +1 @@
-{"ARAVA": 2.7803840561812248, "BUDESONIDE": 3.831470974777136, "ELIQUIS": 1.245910594293252, "MELATONIN": 32.09815881046842, "SUTENT": 1.63548403616663, "TOZINAMERAN": 1.9123702208641424, "null": 1.2288779650438892}
\ No newline at end of file
+{"null": 3.717342611647848}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3037.json
index d68263666c1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3037.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3037.json
@@ -1 +1 @@
-{"null": 3.2191414182460285}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3038.json
index 87d57f05ebd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3038.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3038.json
@@ -1 +1 @@
-{"null": 1.2958054556001122}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3039.json
index 8d687342f37..72a38f0b2b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3039.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3039.json
@@ -1 +1 @@
-{"GARDASIL": 4.20169660850503, "SHINGRIX": 6.768377804158275, "SPIKEVAX": 1.1723108434756464, "TOZINAMERAN": 1.7946115151457849, "null": 1.2607777336075427}
\ No newline at end of file
+{"null": 10.335223072367375}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/304.json
index fb7c25039c4..fbc54c8f77b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/304.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/304.json
@@ -1 +1 @@
-{"ADALIMUMAB": 5.555265291000941, "ARAVA": 6.724996482387304, "OMALIZUMAB": 28.60604262039675, "TOZINAMERAN": 1.1217937373275044}
\ No newline at end of file
+{"COMIRNATY": 4.499670795950392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3040.json
index 8ac16de36bc..e6d6d7debaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3040.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3040.json
@@ -1 +1 @@
-{"COMIRNATY": 2.2035220165062155, "VAXZEVRIA": 2.5615433601999325}
\ No newline at end of file
+{"null": 2.2244759439676507}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3041.json
index 6f05c41d2fd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3041.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3041.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.436600990067784}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3042.json
index 9d1572a9df9..85787f5b529 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3042.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3042.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9355936431816223, "SPIKEVAX": 1.0106218231227908, "TOZINAMERAN": 1.0368879944099625, "null": 1.0687780925359789}
\ No newline at end of file
+{"null": 3.1764301432564133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3043.json
index 3fb85dd8441..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3043.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3043.json
@@ -1 +1 @@
-{"null": 1.768847269306659}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3044.json
index c40bb167826..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3044.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3044.json
@@ -1 +1 @@
-{"DULOXETINE": 122.53886769714096}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3045.json
index 9046b2f8fee..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3045.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3045.json
@@ -1 +1 @@
-{"COMIRNATY": 8.311033944431344}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3046.json
index 43be1b6e840..85787f5b529 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3046.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3046.json
@@ -1 +1 @@
-{"AFINITOR": 2.2329637381596434, "ALIMTA": 2.545970090401545, "AMIKACIN": 1.9483154107511365, "BETMIGA": 7.685191081438687, "BRIDION": 13.407298915818965, "COAPROVEL": 1.925362541538886, "EVEROLIMUS": 3.2907684808401663, "EXFORGE": 1.657589130814371, "EYLEA": 1.2337623269198044, "GLIVEC": 7.052587376183572, "HYDROCORTISONE": 1.5151718297383674, "LEVOFLOXACIN": 1.7871777859990434, "MMRVAXPRO": 1.8929433444839268, "NEVANAC": 8.951055236548877, "NORVIR": 4.209716842282538, "ONCASPAR": 9.766366263828298, "PEMETREXED": 5.943825526776097, "RASILEZ": 2.5551337913991423, "ROACTEMRA": 1.4939118411107215, "SUTENT": 2.043527707878632, "TOBRAMYCIN": 5.160497237279721, "TOPOTECAN": 23.55041516799586, "XOLAIR": 1.3324824888717317, "null": 2.852397454504708}
\ No newline at end of file
+{"null": 3.1764301432564133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3047.json
index a7ac4f740ce..5e1dacbb753 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3047.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3047.json
@@ -1 +1 @@
-{"null": 1.186077944205506}
\ No newline at end of file
+{"null": 1.574165341041632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3048.json
index eee25f51687..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3048.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3048.json
@@ -1 +1 @@
-{"COMIRNATY": 1.886623168971933, "COVID19": 1.4253356509921935, "SUTENT": 2.306487337593943, "TOZINAMERAN": 2.6037313011132275, "VAXZEVRIA": 1.0132300519785018}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3049.json
index 1fbe1915b42..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3049.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3049.json
@@ -1 +1 @@
-{"ABACAVIR": 22.46328883559437, "ABILIFY": 1.5195247312206834, "ATAZANAVIR": 24.287355271893244, "CRIXIVAN": 31.305880577446903, "ENFUVIRTIDE": 108.78052370969765, "FENTANYL": 1.8264835117847704, "GARDASIL": 1.1394323432554825, "KALETRA": 2.81837382571774, "KEYTRUDA": 6.523114892462552, "METHOTREXATE": 1.00266871443076, "OPDIVO": 5.760881421450782, "PEGINTRON": 1.1733931547813388, "PEMBROLIZUMAB": 4.887155769292368, "SAQUINAVIR": 300.42700844247446, "SHINGRIX": 1.29786298255023, "SOLIRIS": 2.8590461622136334, "TOPOTECAN": 32.60504106935826, "TOZINAMERAN": 1.37822781796034, "XOLAIR": 1.0672572922191448, "ZOSTAVAX": 3.340530579989222}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/305.json
index 136cf4d0453..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/305.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/305.json
@@ -1 +1 @@
-{"HEXYON": 610.2763127030163, "INFANRIX": 68.33082693779392, "MMRVAXPRO": 126.83694354529229, "OMALIZUMAB": 10.359655157342216, "PREVENAR": 103.4896340748829, "TWINRIX": 31.208132785762515}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3050.json
index 395564b9fc0..679f64395f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3050.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3050.json
@@ -1 +1 @@
-{"null": 3.109802340156836}
\ No newline at end of file
+{"null": 3.5690720983346997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3051.json
index d6db2bf9e94..7cbc26699c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3051.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3051.json
@@ -1 +1 @@
-{"COVID19": 1.1313639401116404, "TOZINAMERAN": 1.751030983170767}
\ No newline at end of file
+{"null": 4.983358890276996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3052.json
index 122678917d3..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3052.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3052.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4711961112766736, "null": 1.0451816608723243}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3053.json
index e02f77e8969..38081b8fef3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3053.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3053.json
@@ -1 +1 @@
-{"TOZINAMERAN": 2.229524619315152, "null": 1.5566240732873835}
\ No newline at end of file
+{"null": 1.662163173378144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3054.json
index 2f7d62a2844..1aa418d4628 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3054.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3054.json
@@ -1 +1 @@
-{"ESOMEPRAZOLE": 464.32046200070266}
\ No newline at end of file
+{"null": 7.810413205555175}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3055.json
index ca6f694b33f..700a68daac5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3055.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3055.json
@@ -1 +1 @@
-{"MEPOLIZUMAB": 50.55608645688515, "OMALIZUMAB": 270.0282804360942, "XOLAIR": 74.0900143252954}
\ No newline at end of file
+{"null": 2.3225705684559967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3056.json
index 99297f0739d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3056.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3056.json
@@ -1 +1 @@
-{"BIKTARVY": 7.775094238083694, "CYMBALTA": 1.314071629119517, "ELIQUIS": 2.129853767681076, "GARDASIL": 4.792482205430915, "HUMALOG": 2.2148289353621884, "KEPPRA": 4.789868505827508, "LANTUS": 1.9551683952075951, "SUTENT": 1.4550969797571751, "TOZINAMERAN": 1.28324319098494, "null": 1.1130059977857076}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3057.json
index 0cd294ab7fd..cd6a488d6b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3057.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3057.json
@@ -1 +1 @@
-{"AERIUS": 2.8179169035086065, "AFINITOR": 1.2196991519789455, "ALDARA": 1.8438180722275457, "ALIMTA": 1.4458989216827651, "APROVEL": 2.664520571567422, "ASPARAGINASE": 1.388689206275039, "ATAZANAVIR": 1.646244717984063, "AVAPRITINIB": 43.97098945438533, "BETMIGA": 1.278849093142079, "BINOCRIT": 8.155972602707898, "BONVIVA": 1.6074002987426843, "BRIDION": 2.453518747916452, "BUDESONIDE": 1.0275395790633366, "CAELYX": 1.2342639430281734, "CANCIDAS": 1.3931982122728437, "COAPROVEL": 1.9847746773484047, "COMBIVIR": 1.3495383456229264, "COTELLIC": 6.139019589925036, "DESLORATADINE": 2.386858346690652, "EMEND": 1.7369561385129793, "EMTRICITABINE": 1.3020454097424288, "EUCREAS": 1.5856294711790984, "EXFORGE": 3.1845933534942628, "GALVUS": 2.042691965661161, "GLIVEC": 4.190474902876286, "IBUPROFEN": 1.0970062880008955, "IMATINIB": 1.5483502756391705, "INCIVO": 4.428952767510319, "INTRONA": 1.135069512512093, "ISENTRESS": 1.5109451007955634, "KYMRIAH": 1.0483636077563163, "LEVOFLOXACIN": 2.3360535632735577, "LYRICA": 1.4421583948060068, "MICARDIS": 2.666401938327362, "NORVIR": 1.5751248189126166, "NOXAFIL": 1.1307696985968765, "ONCASPAR": 6.828729344336477, "PEGINTERFERON": 1.5336477518160738, "PEGINTRON": 1.262158159572213, "PROTELOS": 4.124734742946936, "RASILEZ": 6.311605107907201, "RELVAR": 1.6238878303871618, "ROACTEMRA": 1.9899690568578643, "SPRYCEL": 1.2332600394341715, "SUFENTANIL": 1.3638685808100464, "SUTENT": 1.5478202335575586, "TAMIFLU": 1.482281001813918, "TELMISARTAN": 1.7476248168748358, "TORISEL": 1.2656498356839978, "VALSARTAN": 1.943384676387828, "XOLAIR": 1.106702046453887, "ZARZIO": 6.011509277355587, "ZELBORAF": 3.707722710651326, "null": 3.082956424073913}
\ No newline at end of file
+{"null": 1.0160645214141928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3058.json
index e642fcb734d..ccb20814a20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3058.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3058.json
@@ -1 +1 @@
-{"ABATACEPT": 51.00714681532218, "ADALIMUMAB": 88.47905841953924, "APREMILAST": 44.73696129518514, "APREPITANT": 9.568040256098945, "ARAVA": 7.414104810804019, "ATRIPLA": 1.190975449729602, "CIMZIA": 3.2547225752119027, "COSENTYX": 3.220238694208837, "RITUXIMAB": 2.186981202173793, "ZOSTAVAX": 1.81285195432494}
\ No newline at end of file
+{"null": 1.0088296720616217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3059.json
index b2cf7fff36d..450b4fd133c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3059.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3059.json
@@ -1 +1 @@
-{"COMIRNATY": 2.032958747477779, "SUBOXONE": 6.600815970740218, "TOZINAMERAN": 1.0682341756882938, "VAXZEVRIA": 1.6076347795712835}
\ No newline at end of file
+{"null": 1.4631329108364377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/306.json
index 3da1ddfbb70..2b9686f1d85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/306.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/306.json
@@ -1 +1 @@
-{"OMALIZUMAB": 169.27800812603675}
\ No newline at end of file
+{"COMIRNATY": 4.451759235938949, "SPIKEVAX": 6.470529799971942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3060.json
index a446cc72ef3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3060.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3060.json
@@ -1 +1 @@
-{"COMIRNATY": 3.521024837746995, "NUCALA": 5.504395214122872, "SPIKEVAX": 2.0402698263044114, "TOZINAMERAN": 3.7192464605949, "VAXZEVRIA": 2.7881145802158858}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3061.json
index 8cc721c4a7e..9a5c5e4a0fd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3061.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3061.json
@@ -1 +1 @@
-{"COMIRNATY": 6.407483561201405}
\ No newline at end of file
+{"null": 2.9447705698214093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3062.json
index fff35954fc0..ee06844f351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3062.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3062.json
@@ -1 +1 @@
-{"COMIRNATY": 2.382157763727566, "TOZINAMERAN": 1.9051165173673803, "VAXZEVRIA": 1.3560053084522807}
\ No newline at end of file
+{"null": 2.376183710662081}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3063.json
index fc9d5f8d05e..7891d5b06f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3063.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3063.json
@@ -1 +1 @@
-{"APIXABAN": 32.94053687440106, "AUBAGIO": 1.3480880026422668, "AVAMYS": 1.73400572403933, "BENLYSTA": 1.8964620868092412, "COMIRNATY": 1.84805076506388, "COVID19": 1.4401016304471708, "DULOXETINE": 1.526474790465319, "ENBREL": 1.185680160214887, "EYLEA": 1.5985218979532485, "FAMPYRA": 6.99874061094816, "GARDASIL": 1.327331143118217, "SHINGRIX": 4.525290989994191, "SPIKEVAX": 1.186794170138243, "TOZINAMERAN": 3.598902133497389, "TWINRIX": 2.251261880065717, "VAXZEVRIA": 1.2541009914415, "VFEND": 1.3509411031588117, "ZOSTAVAX": 3.5606281674251994}
\ No newline at end of file
+{"KEPPRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3064.json
index b678ccc5c60..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3064.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3064.json
@@ -1 +1 @@
-{"AMIKACIN": 1.0951138113265382, "BRAFTOVI": 1.2605118801740351, "CANCIDAS": 1.6157271709073264, "CANNABIDIOL": 6.029554301778748, "CELECOXIB": 1.3282574894650567, "COMIRNATY": 3.669167530961314, "ESOMEPRAZOLE": 4.414511469384312, "GARDASIL": 2.1577155711032687, "INTRONA": 2.0666796156607155, "IPILIMUMAB": 1.9626721413345556, "MENVEO": 1.6117680859272194, "OPDIVO": 1.3193914969317322, "PEGINTRON": 2.5092059960530646, "REBETOL": 2.117406766195512, "SHINGRIX": 2.898783531907706, "SPIKEVAX": 1.8687883387150297, "STELARA": 1.013216032436589, "TASIGNA": 1.5954528578293423, "TOZINAMERAN": 3.2236443196355293, "TWINRIX": 1.6928434670205226, "VAXZEVRIA": 1.0998479701630428, "ZOSTAVAX": 1.5719468131678922}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3065.json
index 91a49b8a5c3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3065.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3065.json
@@ -1 +1 @@
-{"BRILIQUE": 2.1393421651265827, "COMIRNATY": 4.797193433870077, "COVID19": 1.026272167488553, "GARDASIL": 3.676057971027796, "ROACTEMRA": 1.6904614895319032, "SHINGRIX": 2.7140209439453, "SPIKEVAX": 1.7725575788895092, "TOZINAMERAN": 1.1299017565172151, "TWINRIX": 15.845972085007704, "VAXZEVRIA": 1.568577209112729}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3066.json
index 09a0a546412..37f565f86fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3066.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3066.json
@@ -1 +1 @@
-{"CYMBALTA": 5.82919366512467, "GARDASIL": 3.9651869570284375, "TOZINAMERAN": 3.5375649423788067, "null": 1.0380334707447243}
\ No newline at end of file
+{"null": 0.8145643285262828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3067.json
index 2ada0721187..f47f54ef190 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3067.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3067.json
@@ -1 +1 @@
-{"ABACAVIR": 31.997446216782944, "EPIVIR": 197.20698136397948}
\ No newline at end of file
+{"null": 7.574671030412715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3068.json
index 90091537395..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3068.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3068.json
@@ -1 +1 @@
-{"null": 6.952804379260789}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3069.json
index 61f9fea359d..8b47c3733f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3069.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3069.json
@@ -1 +1 @@
-{"APIXABAN": 42.85369962587031, "BUDESONIDE": 44.04725409756571}
\ No newline at end of file
+{"NAGLAZYME": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/307.json
index fcfd9486249..f6a7ba79b27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/307.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/307.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7562474669437422, "CYMBALTA": 1.8440086270592744, "GARDASIL": 11.178778725263795, "NIMENRIX": 11.163051616019644, "SPIKEVAX": 2.107029929152417, "TOZINAMERAN": 8.866918944504551, "ZOSTAVAX": 13.050485509992846}
\ No newline at end of file
+{"COMIRNATY": 4.3172654387721074, "SPIKEVAX": 3.3853599431191803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3070.json
index 5107f31dd4a..eddfd320d01 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3070.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3070.json
@@ -1 +1 @@
-{"null": 1.3001172058324495}
\ No newline at end of file
+{"CELLCEPT": 6.504272280025555, "COMIRNATY": 0.115287167157896, "ENTRESTO": 8.384737529573558, "OPSUMIT": 11.67810399911357, "TRACLEER": 33.590721466936046, "null": 1.563752070785223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3071.json
index e7a6772d8b6..902e5b7eea5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3071.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3071.json
@@ -1 +1 @@
-{"null": 2.654715123360537}
\ No newline at end of file
+{"ENTECAVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3072.json
index 12c10f1bf39..006bd0d9b5f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3072.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3072.json
@@ -1 +1 @@
-{"NOVOSEVEN": 5911.667594544416}
\ No newline at end of file
+{"ALISKIREN": 920.3623044209572, "null": 1.040710572737965}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3073.json
index 9e73d47154a..e641aff115e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3073.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3073.json
@@ -1 +1 @@
-{"null": 1.019336760690982}
\ No newline at end of file
+{"null": 3.360667638194712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3074.json
index 286ea87cbd8..4c0646ef5c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3074.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3074.json
@@ -1 +1 @@
-{"ADVATE": 7454.559016309977, "ELOCTA": 1020.4188000615862, "EPTACOG": 284.07402197546674, "HELIXATE": 2562.360690650658, "KOGENATE": 2221.579916647552, "NOVOSEVEN": 30.2553417773186, "OCTOCOG": 1707.5779513017712, "PEGINTERFERON": 4.734202100470303}
\ No newline at end of file
+{"null": 2.530447090273517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3075.json
index 885cd7e549a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3075.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3075.json
@@ -1 +1 @@
-{"null": 1.3429555258382595}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3076.json
index 1bafe7cd770..a69846ea5de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3076.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3076.json
@@ -1 +1 @@
-{"STELARA": 207.83064511139128}
\ No newline at end of file
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3077.json
index 3ecfb538229..5e56f984b15 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3077.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3077.json
@@ -1 +1 @@
-{"ENTYVIO": 87.0223080114107, "STELARA": 120.084180795123}
\ No newline at end of file
+{"null": 2.634029858685966}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3078.json
index 2b25e664b62..cb8c39b1dbc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3078.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3078.json
@@ -1 +1 @@
-{"ADALIMUMAB": 6.360529374666531, "AZATHIOPRINE": 17.769401386261116, "BUDESONIDE": 16.052752804414364, "COSENTYX": 6.0129409029097545, "ENTYVIO": 76.9701781326249, "HUMIRA": 40.01812721442777, "INFLIXIMAB": 44.399033910541874, "RINVOQ": 23.452166121700063, "SIMPONI": 4.653970476897955, "STELARA": 25.701871949285337, "XELJANZ": 26.2301529920589}
\ No newline at end of file
+{"null": 1.4464217030420925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3079.json
index 88eb5ed74b1..aba5ec10c7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3079.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3079.json
@@ -1 +1 @@
-{"XELODA": 255.86707061670367, "null": 1.8516550839198065}
\ No newline at end of file
+{"null": 3.012590731096915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/308.json
index 10d875e7364..e6e67aee351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/308.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/308.json
@@ -1 +1 @@
-{"COMIRNATY": 1.347368651850589, "COVID19": 1.732308982336152, "DULOXETINE": 11.698582920616234, "FENTANYL": 11.039151617949608, "GARDASIL": 8.299626783196151, "QUTENZA": 49.4717389225508, "SHINGRIX": 5.414745025642478, "VAXZEVRIA": 1.053222153477017}
\ No newline at end of file
+{"null": 1.5228310199198265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3080.json
index 97cd350d1ef..5811ee71a76 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3080.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3080.json
@@ -1 +1 @@
-{"null": 1.316189535494361}
\ No newline at end of file
+{"null": 21.39937505661956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3081.json
index 5147e469334..80cc047a6df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3081.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3081.json
@@ -1 +1 @@
-{"null": 2.125622382723944}
\ No newline at end of file
+{"BRILIQUE": 7.0765290902506335, "CLOPIDOGREL": 10.005150471794522, "COMIRNATY": 0.884942936727996, "ELIQUIS": 8.344869356926049, "ENOXAPARIN": 4.899984886437539, "EYLEA": 21.50838740417052, "HUMALOG": 0.5025920223682093, "LIXIANA": 10.076311803848563, "MODERNA": 1.1749361862148913, "NEXAVAR": 0.8188624112388814, "PLAVIX": 8.763192351740049, "SPIKEVAX": 0.5106385240409782, "SUTENT": 1.2762708434819157, "TASIGNA": 1.434797797957628, "TICAGRELOR": 10.210196166291176, "TOZINAMERAN": 1.024768896679726, "VAXZEVRIA": 1.0719127017927816, "VIAGRA": 2.417908368677417, "null": 1.2058975447487643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3082.json
index c90ca5b001e..ad2ddfe7473 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3082.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3082.json
@@ -1 +1 @@
-{"null": 1.2706252307038903}
\ No newline at end of file
+{"AZOPT": 43.730374107185526, "BEOVU": 12.886013369570108, "CICLOSPORIN": 1.2715705164240056, "CLOPIDOGREL": 0.7357584280795206, "COMIRNATY": 0.4374487221533347, "DEXAMETHASONE": 1.3328950627110596, "EYLEA": 8.679608134299755, "IBUPROFEN": 2.098918728544862, "LEVETIRACETAM": 2.1527398136336577, "LEVOFLOXACIN": 3.309554031317577, "MMRVAXPRO": 2.807183475292194, "NEVANAC": 29.338215224253343, "NEVIRAPINE": 21.831025787312583, "ONCASPAR": 13.5280991503291, "SPIKEVAX": 0.114713327275552, "TAMIFLU": 2.0502722129183675, "TOZINAMERAN": 0.189801729464134, "VAXZEVRIA": 0.097997791457681, "ZOSTAVAX": 0.8445273762470712, "null": 3.259250456052184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3083.json
index 2ef1f56164e..0836fd50536 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3083.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3083.json
@@ -1 +1 @@
-{"ABILIFY": 1.8475711834876412, "AIMOVIG": 6.849467924341745, "CLOPIDOGREL": 2.1016806750942885, "CYMBALTA": 1.804391135753557, "FENTANYL": 3.01628314105686, "FORSTEO": 1.8660191884220017, "JANUMET": 3.5741059461158784, "KEPPRA": 1.668852917836788, "KIVEXA": 34.57568742409237, "OLANZAPINE": 6.012244796546263, "SPINRAZA": 6.859016139206288, "SUBOXONE": 1.668256461043853, "TOVIAZ": 6.322670950683489, "VELTASSA": 19.02855262070299, "ZYPREXA": 2.451650984361995, "null": 2.816818709399569}
\ No newline at end of file
+{"COMIRNATY": 0.6096897551174332, "null": 1.5504555782731224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3084.json
index 6d03a55007a..53739f56d4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3084.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3084.json
@@ -1 +1 @@
-{"AFINITOR": 2.1523963114399183, "BRILIQUE": 3.233995014103168, "BUMETANIDE": 22.72127019674856, "CLOPIDOGREL": 14.034428357217305, "ELIQUIS": 6.109531738890694, "ENOXAPARIN": 1.734181829103821, "ENZALUTAMIDE": 4.086715239920283, "EXJADE": 2.8929527530932333, "FORSTEO": 1.1524454342023185, "GLYCOPYRRONIUM": 5.918613933203575, "HARVONI": 1.3654484329738967, "IBUPROFEN": 1.6102651057292292, "JAKAVI": 1.046515006031007, "JANUVIA": 1.190693425568124, "KALETRA": 1.8215089692461124, "LIXIANA": 9.728128382810135, "MICARDIS": 2.0672971101502875, "NEXAVAR": 3.241241134641345, "OFEV": 2.76097139749974, "OPSUMIT": 1.78064928221551, "PASIREOTIDE": 49.47961987141578, "PEGASYS": 1.5681755675038271, "PEGINTRON": 1.0564283422538685, "PLAVIX": 10.375083645609507, "PRADAXA": 3.6572667401456633, "REVATIO": 1.4507041849682374, "ROTATEQ": 23.57647510891971, "SPRYCEL": 1.416021950447183, "STIVARGA": 2.045355825407793, "SUTENT": 2.147151199321915, "TAMIFLU": 2.5203141312227006, "TICAGRELOR": 16.77884091353526, "TWINRIX": 1.3140353321399787, "VOTRIENT": 1.7409794716096454, "XARELTO": 2.1264585238691427, "null": 1.9342303669369951}
\ No newline at end of file
+{"IXIARO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3085.json
index 62f31665e4a..abb2bdfc7d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3085.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3085.json
@@ -1 +1 @@
-{"AIMOVIG": 9.385272073359168, "CLOPIDOGREL": 2.8722254461183514, "ENTRESTO": 2.565934927019133, "ENTYVIO": 5.766441460172619, "JARDIANCE": 3.6322357387733226, "SUTENT": 1.5395245330209126, "TEDUGLUTIDE": 250.41818787072893, "TRULICITY": 6.124392695066311, "VELTASSA": 26.004480889399872, "XELJANZ": 1.9660394113548705, "XTANDI": 2.7048557744654835, "null": 2.038881743899592}
\ No newline at end of file
+{"COMIRNATY": 0.3025530511576974, "null": 3.5551684193342497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3086.json
index 24356520d22..5a07b3bb90e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3086.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3086.json
@@ -1 +1 @@
-{"PEGASYS": 1.40063931622347, "ROTATEQ": 11.023061783310832, "XELJANZ": 2.1374552083152025, "null": 2.5332242044362623}
\ No newline at end of file
+{"BUPIVACAINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3087.json
index d56a75bc038..627fcfaa604 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3087.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3087.json
@@ -1 +1 @@
-{"AVASTIN": 4.149022194990533, "BOSULIF": 8.588930549754554, "BUDESONIDE": 1.1079909944659785, "CAPECITABINE": 3.643732549835821, "CELLCEPT": 5.716870511229147, "CLOPIDOGREL": 1.978276077859004, "DEXAMETHASONE": 2.213127954856789, "ENTYVIO": 11.18530217537436, "HUMIRA": 12.464777516777728, "IBRANCE": 1.412158771213271, "INFLIXIMAB": 30.192664472519443, "INLYTA": 2.982929618361298, "KEYTRUDA": 1.6834447154087575, "LUTATHERA": 27.946625081114437, "LUTETIUM": 61.352075302252274, "NEXAVAR": 1.5386221160182758, "OFEV": 27.11674947633393, "ROTATEQ": 9.737524210947472, "SUTENT": 2.475496174019185, "XELJANZ": 4.561286147344739, "XTANDI": 1.2497071399133342, "null": 1.16458524668616}
\ No newline at end of file
+{"CLOPIDOGREL": 64.62497286823836, "null": 0.5524584447875045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3088.json
index 1e75cb6d2da..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3088.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3088.json
@@ -1 +1 @@
-{"BUPIVACAINE": 511.034546531061}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3089.json
index 2c968b4a799..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3089.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3089.json
@@ -1 +1 @@
-{"null": 2.3793318554953204}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/309.json
index f5a59a66ce8..056e5b4282b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/309.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/309.json
@@ -1 +1 @@
-{"CYTARABINE": 25.408759514637143, "ICLUSIG": 129.94614167075676}
\ No newline at end of file
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3090.json
index 1bfd97d384b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3090.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3090.json
@@ -1 +1 @@
-{"REMICADE": 228.65543822595637, "null": 1.3584610935831385}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3091.json
index e653cbf6bfa..95d54906558 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3091.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3091.json
@@ -1 +1 @@
-{"GARDASIL": 88.78244063081932, "null": 1.1422885138152594}
\ No newline at end of file
+{"null": 0.6110021031734242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3092.json
index fcfb56c01eb..5572a48e839 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3092.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3092.json
@@ -1 +1 @@
-{"ELIQUIS": 159.78187428899716, "JARDIANCE": 28.143386811326703}
\ No newline at end of file
+{"null": 2.8146059565219343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3093.json
index cf00af28612..30120efc5d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3093.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3093.json
@@ -1 +1 @@
-{"BYETTA": 4.205563974512833, "CICLOSPORIN": 1.123324513256622, "CRIZOTINIB": 120.43850822071887, "DEXAMETHASONE": 2.933536706382696, "EPIVIR": 14.384959634017967, "EXJADE": 2.341738829912798, "FIRDAPSE": 11.745868033030764, "JANUMET": 6.882051143515353, "JANUVIA": 3.8423422431972822, "KEPPRA": 1.091194764617819, "KEYTRUDA": 1.139384125830649, "LAMIVUDINE": 11.808773758426742, "NPLATE": 8.235299558146043, "ORKAMBI": 14.970730733254054, "PEGASYS": 4.895895703818265, "ROTATEQ": 12.46705238011334, "SUBOXONE": 5.414494186369426, "SUTENT": 1.4068524040737451, "SYNAGIS": 22.67603657821293, "TRACLEER": 3.595594437885426, "XTANDI": 4.361504152245531, "null": 1.385296219161796}
\ No newline at end of file
+{"ABILIFY": 1.8877014274933173, "ADALIMUMAB": 0.3823564932427202, "AFINITOR": 0.8680815332116093, "ALIMTA": 4.653762108630027, "AP": 236.7319672946979, "ARAVA": 0.1766020226940039, "ARIPIPRAZOLE": 1.6385490075423357, "AUBAGIO": 0.4171484932285947, "BUSULFAN": 0.9475661123394736, "CELLCEPT": 0.5400920704194296, "CETUXIMAB": 8.907819543092893, "CHAMPIX": 0.3845882751415479, "CICLOSPORIN": 0.6897848861126963, "CIMZIA": 0.8184832744915311, "CLOPIDOGREL": 0.7289984699557799, "COMIRNATY": 0.6855318918211151, "COSENTYX": 3.195657313337444, "COTELLIC": 4.028240801491386, "CRIXIVAN": 3.1923777336566554, "CYMBALTA": 0.1398706266361727, "DEXAMETHASONE": 0.9994209369465036, "DOCETAXEL": 0.9951591325985832, "ELIQUIS": 0.2487459971689171, "ENBREL": 0.7286310188448579, "ENTYVIO": 1.191546209478703, "ERBITUX": 8.379775585948028, "EXJADE": 0.5184103793110925, "EYLEA": 2.2246829258318703, "FASENRA": 1.5461333792492304, "FORSTEO": 0.3438996733818266, "GARDASIL": 0.7226429123687288, "GLIBENCLAMIDE": 4.372939724984836, "HALAVEN": 2.4274476494459893, "IBRANCE": 0.4564859278378766, "IBUPROFEN": 0.7318382233880972, "INFANRIX": 6.216057018745153, "IPILIMUMAB": 1.1452381777538636, "IRESSA": 1.782039051083561, "IRINOTECAN": 2.425030026666377, "KEPPRA": 0.21330755512754, "KEYTRUDA": 0.8507193136082611, "LAMIVUDINE": 2.0377013114823663, "MEKINIST": 1.0519622517821037, "MEPOLIZUMAB": 0.709301152781735, "METHOTREXATE": 1.0461914130557135, "MMRVAXPRO": 18.754667283918312, "MODERNA": 0.5669842580927669, "NEVANAC": 8.400171226177648, "NEVIRAPINE": 8.519764558896153, "NEXAVAR": 0.5940857071549605, "NIMENRIX": 1.2894710067211332, "NORVIR": 2.0567808723047305, "NUCALA": 0.7394741489850566, "OLANZAPINE": 0.5402287455826742, "OPDIVO": 1.0028561243129428, "PANITUMUMAB": 14.84816037599784, "PEGASYS": 0.5582173559627016, "PEGINTRON": 0.2959291371022385, "PEMBROLIZUMAB": 2.27775391484738, "PLAVIX": 0.4182710833904428, "PREVENAR": 5.453063070562339, "RINVOQ": 1.8219711951735256, "RITUXIMAB": 0.6604724952137735, "ROACTEMRA": 2.7055469781469523, "ROTATEQ": 1.80845497800706, "SHINGRIX": 0.3378225549188144, "SIMPONI": 1.2518120749092498, "SPIKEVAX": 0.3250668762939694, "STELARA": 1.0700749471621829, "SUFENTANIL": 4.023517925245391, "SUTENT": 0.6730258876474933, "SYNAGIS": 2.320389870670283, "TAGRISSO": 2.064826211216725, "TAMIFLU": 2.129218440977306, "TASIGNA": 1.3192846270981256, "TOBRAMYCIN": 4.69846648538013, "TOZINAMERAN": 0.4671528212096607, "TWINRIX": 1.865195572979876, "VAXZEVRIA": 0.3215676865042332, "VECTIBIX": 13.375080194716892, "VIRAMUNE": 7.450527180532714, "XELJANZ": 0.7060710574703168, "XOLAIR": 1.092396522188849, "YERVOY": 3.0194215175323427, "ZELBORAF": 4.289907678071463, "ZIAGEN": 9.77045401966187, "ZOSTAVAX": 1.840849625639865, "ZYPREXA": 0.355124570697634, "null": 1.6704959677061484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3094.json
index 8f6b61eb2db..b791a2e4d5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3094.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3094.json
@@ -1 +1 @@
-{"ABILIFY": 1.3257650666226146, "ACLASTA": 1.0288792607839146, "ACTOS": 1.3729591090680346, "ACTRAPID": 1.1497609715805055, "ADCIRCA": 2.7224344957079696, "ADEMPAS": 1.120683417898721, "ADVATE": 3.152567935687556, "AERIUS": 2.163979147450486, "ALISKIREN": 7.176319497335696, "AMBRISENTAN": 1.1233544404615932, "AMBROXOL": 14.23524208288276, "AMLODIPINE": 11.897991469564742, "APIDRA": 1.9350097924208984, "APROVEL": 2.9190262884738365, "ARANESP": 1.0402017291086385, "AUBAGIO": 4.823870448717509, "AVONEX": 2.2505888632388173, "AZILECT": 4.031295360698806, "BENRALIZUMAB": 3.683763555687933, "BETMIGA": 1.1981409955837687, "BEXTRA": 1.6691487175880533, "BIKTARVY": 1.0425322044613887, "BONVIVA": 2.630259655638741, "BOSULIF": 1.179662270595573, "BRIVIACT": 1.636011268763425, "BUPIVACAINE": 1.6238064004709143, "BUPRENORPHINE": 1.409089063681308, "BYDUREON": 1.3338484840999745, "BYETTA": 1.3756469776230915, "CAFFEINE": 8.56948865199568, "CAPRELSA": 1.0355646598749797, "CARBIDOPA": 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1.6334110053666846, "null": 1.5904551475862352}
\ No newline at end of file
+{"ANORO": 501.8586392072335, "APIXABAN": 75.2711405385109, "AZATHIOPRINE": 26.38520602580797, "COMIRNATY": 0.2726679965533522, "SPIKEVAX": 0.0983212805881584, "ZOSTAVAX": 3.930947105429405, "null": 0.8240028972909227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3095.json
index 4cca78c257d..47d21ba0577 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3095.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3095.json
@@ -1 +1 @@
-{"null": 8.99204728137524}
\ No newline at end of file
+{"null": 0.9701319051974288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3096.json
index 418e601c02a..c1bbb4b698c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3096.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3096.json
@@ -1 +1 @@
-{"null": 4.688436715608479}
\ No newline at end of file
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3097.json
index bef0c1472aa..ca34fb0c063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3097.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3097.json
@@ -1 +1 @@
-{"null": 2.0015339580178004}
\ No newline at end of file
+{"CLOFARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3098.json
index 54ee64f2929..139850fda2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3098.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3098.json
@@ -1 +1 @@
-{"null": 1.910040633304925}
\ No newline at end of file
+{"ZOSTAVAX": 21.88346872113676, "null": 0.3174481214266242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3099.json
index fdffa6dd24c..f078491a407 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3099.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3099.json
@@ -1 +1 @@
-{"null": 1.7203581838430817}
\ No newline at end of file
+{"COMIRNATY": 0.7224905012594292, "GARDASIL": 7.184985016512057, "PEGINTRON": 11.53237051439903, "TOZINAMERAN": 0.6543363418424886, "VAXZEVRIA": 0.2566330469729619, "null": 1.0300238056584254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/31.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/31.json
index 7e303a51a46..e0c8e783027 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/31.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/31.json
@@ -1 +1 @@
-{"ABACAVIR": 1.6609913631815771, "AIMOVIG": 1.87282831807099, "ATRIPLA": 1.201729856043155, "AZILECT": 7.453715920437804, "BIKTARVY": 16.211473568022807, "BRINTELLIX": 14.619609380843826, "CHAMPIX": 57.498055495201605, "CIRCADIN": 11.465604490786784, "COMBIVIR": 2.402627690194404, "CYMBALTA": 1.7009953439110723, "DESCOVY": 5.25433925655206, "EFAVIRENZ": 2.6132998755463577, "GENVOYA": 6.497984733688627, "LATUDA": 1.6447094600110634, "MELATONIN": 7.342563868493295, "SEMAGLUTIDE": 13.85767641076035, "SIFROL": 4.549356890943895, "STALEVO": 2.702998184368318, "SUBOXONE": 1.1771077628590465, "TAMIFLU": 1.2794925741182936, "TIVICAY": 7.369999789464062, "TRIUMEQ": 5.403626924150437, "VARENICLINE": 24.92171622127777, "VFEND": 3.37318621636723, "XTANDI": 1.5013924848012814, "XYREM": 8.91516435096831, "null": 2.080384359713867}
\ No newline at end of file
+{"null": 1.1785490858545478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/310.json
index 1d699340b5f..c6490dabd28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/310.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/310.json
@@ -1 +1 @@
-{"ABATACEPT": 6.1739925216996125, "ACETAMINOPHEN": 7.8681949820267825, "ADALIMUMAB": 9.90363161838252, "AIMOVIG": 5.462579180612203, "ALL": 1.0618875894851585, "ALOXI": 3.578587789463588, "ALPELISIB": 1.0880045769699564, "AMINOSALICYLIC": 1.2519722204874846, "APIXABAN": 2.4631195164543724, "APREMILAST": 4.916715467900437, "APREPITANT": 11.53889758522827, "ARAVA": 12.54852227596196, "ARIXTRA": 1.0843285695754168, "ATEZOLIZUMAB": 1.204463799883224, "AUBAGIO": 11.539627893494584, "BENLYSTA": 1.215272938831676, "BETAFERON": 1.0324487688894528, "BEVACIZUMAB": 1.0680494753276846, "BIKTARVY": 1.414049101529255, "BLINCYTO": 1.9038507267812728, "BOCEPREVIR": 1.0909155287583654, "BRINTELLIX": 1.0894338522025782, "BRIVIACT": 1.122183382349329, "CANNABIDIOL": 1.4150518975817985, "CELLCEPT": 1.2904356331469804, "CETUXIMAB": 1.7121877912131542, "CHEMOTHERAPY": 3.398085329742896, "CIMZIA": 2.5768761062588466, "COTELLIC": 1.1693899608839975, "DACLIZUMAB": 24.773519376552883, "DOCETAXEL": 4.859122999566714, "ELIQUIS": 1.5291272918399077, "ELMIRON": 5.955642799865957, "ENBREL": 2.65383380768433, "ENTYVIO": 1.820429065550237, "ERELZI": 2.277046277937203, "ERENUMAB": 1.317672344777193, "ERIBULIN": 3.04218782886829, "ESMYA": 4.349739511118661, "ETANERCEPT": 1.7893864192902154, "FASLODEX": 2.8396993823035825, "FORSTEO": 1.3817485951146378, "FULVESTRANT": 2.609580771734368, "GARDASIL": 1.1768275379584987, "GILENYA": 1.3235785442968733, "HALAVEN": 4.504042453475993, "HERCEPTIN": 2.758326892691253, "HUMIRA": 1.6092225677509304, "HYCAMTIN": 1.4767885122291495, "HYDROCORTISONE": 1.6288806885276224, "IBRANCE": 6.034025622932893, "IDACIO": 2.5560528388722874, "IMBRUVICA": 1.3132780242367934, "INDINAVIR": 2.045855905600176, "INFERGEN": 2.6576386657225, "INTERFERON": 1.6601746107490707, "INTRONA": 1.409952838219583, "IRINOTECAN": 1.1713798699515217, "KAFTRIO": 1.8198271426867343, "KARVEA": 1.5127140124261969, "KEPPRA": 1.0515945880618884, "KESIMPTA": 2.168174005122785, "KISQALI": 3.0801741479401343, "LEFLUNOMIDE": 1.6673632473212117, "LEMTRADA": 1.000433437961401, "LIXIANA": 2.686328531706262, "LONSURF": 2.278752816790884, "LUPKYNIS": 2.1662788086983205, "LUTATHERA": 3.0420841118096336, "LUTETIUM": 3.763309598438707, "MAVENCLAD": 6.562565434225435, "METHOTREXATE": 1.063804569495675, "MISOPROSTOL": 2.832206746671133, "NEULASTA": 1.1193089561614484, "NEXAVAR": 3.1744523086886707, "NILOTINIB": 1.9258707946153943, "OXYBUTYNIN": 1.1177936595729223, "PACLITAXEL": 2.513743454030984, "PEGASYS": 3.020918928808236, "PEGINTERFERON": 1.6358262609524288, "PEGINTRON": 2.475212123268486, "PLEGRIDY": 1.63241032034053, "POSACONAZOLE": 1.0207482397724752, "POTELIGEO": 1.895824911726377, "PRIORIN": 24.917605499852616, "PROTELOS": 1.534119504232849, "REBETOL": 1.075241758871245, "RIBOCICLIB": 1.5923664082174993, "RINVOQ": 1.4599933816171955, "RITUXIMAB": 1.2539028708704123, "ROACTEMRA": 1.1307509131701527, "RYEQO": 8.309080153397142, "SACITUZUMAB": 9.636692109612964, "SAXENDA": 1.000821099267177, "SIMPONI": 1.1819531211538532, "SORAFENIB": 1.4781960831559442, "SPRYCEL": 1.2161544830720088, "STELARA": 1.7479584540023374, "TAFINLAR": 1.8393381624707692, "TAGRISSO": 1.402679482613175, "TASIGNA": 1.377845918550514, "TAXOTERE": 15.24131808896068, "TEMOZOLOMIDE": 1.3494357471858505, "TERIFLUNOMIDE": 5.218457105556481, "TRAMETINIB": 2.6241823660695704, "TREMFYA": 1.1209082788459444, "TRIUMEQ": 1.6395717959175913, "TRODELVY": 13.07590007382991, "UPADACITINIB": 1.6756061923684853, "VEMURAFENIB": 1.941320067361975, "XELJANZ": 1.0454526586991784, "XOLAIR": 1.4083051601608814, "ZEJULA": 1.3360795260481386, "ZELBORAF": 4.494522325699221, "ZEPATIER": 2.481650002487497, "ZINBRYTA": 4.760617450716126, "ZONISAMIDE": 1.6796216179210883}
\ No newline at end of file
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3100.json
index 8c7670c5dfe..c14446ddbb5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3100.json
@@ -1 +1 @@
-{"BIKTARVY": 326.2548304959832, "null": 1.210200739341985}
\ No newline at end of file
+{"COMIRNATY": 0.1550985956232839, "GARDASIL": 2.911629417832572, "OLANZAPINE": 9.42857192851443, "SPIKEVAX": 0.5405864470173295, "ZYPADHERA": 23.833402679072265, "null": 2.687584533670733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3101.json
index bfc618fe164..8ea8848912b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3101.json
@@ -1 +1 @@
-{"ABACAVIR": 4.361520189598277, "ATAZANAVIR": 11.1244362943146, "ATRIPLA": 2.3685670291799097, "EFAVIRENZ": 15.530059444042344, "EMTRICITABINE": 23.25402452609354, "EXJADE": 8.346222843626329, "HEPSERA": 307.7260100795215, "KALETRA": 56.59854860520182, "LOPINAVIR": 58.01298889648041, "NORVIR": 65.88646132650825, "REYATAZ": 34.118770278916884, "STRIBILD": 6.001312126304554, "TENOFOVIR": 270.4801030760049, "TRUVADA": 15.50414219497317, "VIREAD": 114.53323562815063}
\ No newline at end of file
+{"1": 17.649962607021507, "ABACAVIR": 6.056210504784032, "ABASAGLAR": 0.5838437220038436, "ABATACEPT": 0.0373657744480613, "ABILIFY": 0.9861958416489708, "ABRAXANE": 1.220720319390301, "ACTOS": 0.8408604704813081, "ADALIMUMAB": 0.8151585698988321, "ADCETRIS": 3.403794099978616, "ADCIRCA": 0.8829949730854469, "ADEMPAS": 1.8861208063183488, "ADENURIC": 0.4701656707939805, "AERIUS": 0.3338074978268946, "AFINITOR": 1.5017932569364094, "AIMOVIG": 15.589170233301614, "ALECENSA": 8.640128677945562, "ALEMTUZUMAB": 0.3222761552343263, "ALIGN": 12.740764314155877, "ALIMTA": 1.93864642588466, "ALL": 1.046730139537566, "ALOXI": 2.518250336260491, "AMBROXOL": 20.514520952899133, "AMINOSALICYLIC": 6.48903639271728, "AMLODIPINE": 17.15046578978299, "ANAKINRA": 0.2922007118431955, "ANORO": 0.7315670168758691, "APIDRA": 0.1414274956422497, "APIXABAN": 1.665206946200854, "APREPITANT": 0.3915989555029352, "APROVEL": 1.450015546840958, "ARANESP": 9.738703495245796, "ARAVA": 0.2341753840492688, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3102.json
index 53daae2240b..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3102.json
@@ -1 +1 @@
-{"ABACAVIR": 1.0520586596013328, "ADEFOVIR": 68.25145392066845, "ATAZANAVIR": 7.452611426813426, "ATRIPLA": 19.70103286837864, "EMTRICITABINE": 22.815972031634843, "EMTRIVA": 41.46213260682574, "ENTECAVIR": 18.472107891819284, "EXJADE": 10.560227777051518, "GENVOYA": 17.858175899779543, "HARVONI": 3.110091470457843, "HEPSERA": 486.0392539776995, "KALETRA": 11.446679407010723, "LOPINAVIR": 39.43054365765786, "NORVIR": 13.237790094603763, "REYATAZ": 19.91945074203826, "STRIBILD": 17.07001337853639, "TENOFOVIR": 274.5703555001742, "TRUVADA": 35.27945908165026, "VIREAD": 159.86361809160002}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3103.json
index 7b1a5a8c2e1..5afa18350ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3103.json
@@ -1 +1 @@
-{"JAKAVI": 43.13085105785789}
\ No newline at end of file
+{"VAXZEVRIA": 1.8682173682647143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3104.json
index 6e93f4133a5..cee1931767b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3104.json
@@ -1 +1 @@
-{"null": 1.1646108727749316}
\ No newline at end of file
+{"null": 5.868650777682267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3105.json
index d0d9bc637f7..bffe7ea26d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3105.json
@@ -1 +1 @@
-{"null": 1.0692175350699895}
\ No newline at end of file
+{"null": 1.9444161439271868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3106.json
index 35b87e250a6..8de65608d6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3106.json
@@ -1 +1 @@
-{"null": 3.7005894790151976}
\ No newline at end of file
+{"OCRELIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3107.json
index 79d92a4fc76..7b3aa3a9d26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3107.json
@@ -1 +1 @@
-{"null": 1.3193243928001126}
\ No newline at end of file
+{"null": 1.4308638089904002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3108.json
index cc9fc5765a2..580aa25f5ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3108.json
@@ -1 +1 @@
-{"ENBREL": 22.02210697040369, "null": 1.0114320997185835}
\ No newline at end of file
+{"ABACAVIR": 12.615542890687712, "ABATACEPT": 17.15669557897606, "ACETAMINOPHEN": 18.46441229360237, "ADALIMUMAB": 18.2342716860626, "AIMOVIG": 2.795154230663162, "AMINOSALICYLIC": 1.950182087227108, "ANAKINRA": 21.41225754198536, "APIDRA": 0.4167685672696497, "APIXABAN": 0.4140859240780611, "APREMILAST": 15.695889562123552, "APREPITANT": 19.48181001863859, "ARAVA": 32.500710094480844, "ARIPIPRAZOLE": 0.4950484271631375, "AUBAGIO": 0.1057909924370264, "AZATHIOPRINE": 1.764904717342792, "BOTULINUM": 0.9254666826205132, "BRILIQUE": 0.2862746703136496, "BUDESONIDE": 0.098299152508169, "BUPRENORPHINE": 0.3402860238901722, "CELECOXIB": 0.7401726817429694, "CELLCEPT": 0.1516902109064703, "CERTOLIZUMAB": 5.625805171944957, "CHLORHEXIDINE": 12.315800279230569, "CICLOSPORIN": 0.7494028335061811, "CIMZIA": 9.138520266724, "CLOPIDOGREL": 2.278072221466882, "COMIRNATY": 0.0014985511809154, "COSENTYX": 1.0297293889737462, "CYMBALTA": 0.0850959842336247, "DESLORATADINE": 1.5956761055542763, "DULOXETINE": 0.7570182409841898, "ELIQUIS": 1.3976281457892588, "ENBREL": 13.427607887308238, "ENTRESTO": 6.692959633049774, "ERELZI": 3.3154654912536947, "ERENUMAB": 2.3810260812840407, "ETANERCEPT": 1.6322320782236748, "FAMPYRA": 0.4566105592451349, "FENTANYL": 0.1657829670542334, "HUMIRA": 2.3483631962487768, "IBUPROFEN": 0.2222927970827815, "INFLIXIMAB": 0.8135049350207747, "LATUDA": 0.2460594078333021, "LEFLUNOMIDE": 1.7864412459560886, "LEVOFLOXACIN": 0.2236905674774206, "LIXIANA": 1.2852101797798363, "METFORMIN": 0.9251733694957884, "METHOTREXATE": 0.5682316699605527, "MMRVAXPRO": 0.1306038388166909, "MYCOPHENOLATE": 1.1247725282186962, "OLANZAPINE": 0.236046682134233, "OPSUMIT": 0.1077523298335169, "ORENCIA": 3.83833386111682, "PAXLOVID": 5.171335477168774, "PLAVIX": 0.2003360786805256, "PROPRANOLOL": 1.2524549164120762, "RITUXIMAB": 2.043556897101198, "RIVAROXABAN": 1.5445684187963165, "SELINCRO": 43.16914042468668, "TACROLIMUS": 2.7845585326378406, "TELMISARTAN": 1.054694876289065, "TRELEGY": 0.6123838939807914, "VFEND": 0.1807010092356498, "VIAGRA": 0.1657547800189048, "XARELTO": 1.343952823513223, "XELJANZ": 0.1213840005053805, "XYREM": 0.6990556138102612, "ZOSTAVAX": 0.2631411909048233, "null": 0.3291084756459904}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3109.json
index 63a1a7945ae..f951f07532f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3109.json
@@ -1 +1 @@
-{"ABACAVIR": 54.17487555254509, "ATRIPLA": 4.2693812827298725, "COMBIVIR": 72.58966387499866, "CRIXIVAN": 439.2645132084237, "KALETRA": 46.16965426786876}
\ No newline at end of file
+{"ANORO": 16.00492877015562, "ARAVA": 3.0939379376819365, "CLOPIDOGREL": 4.034043681886868, "COSENTYX": 9.609372475074476, "null": 3.4748121220127826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/311.json
index 55d45a45645..d638a2469ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/311.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/311.json
@@ -1 +1 @@
-{"AUBAGIO": 3.5621348590715063, "CHAMPIX": 1.368102862558494, "COMIRNATY": 2.270664624973621, "DEXAMETHASONE": 1.818610630693425, "DOCETAXEL": 11.62397892148129, "GARDASIL": 2.779844396609774, "HERCEPTIN": 5.853647743634364, "LEMTRADA": 10.662728972050672, "OLOPATADINE": 508.9692650940183, "RINVOQ": 3.372158443839574, "SIMPONI": 2.3484359775252983, "SPIKEVAX": 1.5488753240891548, "STELARA": 4.546974606476146, "TOZINAMERAN": 1.5876127880235835, "XOLAIR": 1.8434775103370469}
\ No newline at end of file
+{"COMIRNATY": 9.050397802821914, "SPIKEVAX": 1.0873447558044738, "VAXZEVRIA": 2.277301453400202, "null": 0.1706805059120663}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3110.json
index 333300014f9..67583d4127b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3110.json
@@ -1 +1 @@
-{"ABACAVIR": 12.454398859117411, "ATRIPLA": 1.8115042435327888, "BIKTARVY": 18.385815114805084, "COMBIVIR": 19.774919774494677, "DESCOVY": 80.4350097828438, "HUMALOG": 4.6365249166886455, "LANTUS": 4.102119489297582, "PEGASYS": 2.1568549551210863}
\ No newline at end of file
+{"CIMZIA": 8.903784433049616, "null": 3.5421037347729047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3111.json
index 1d74dd99d78..ace0291cabf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3111.json
@@ -1 +1 @@
-{"ANAGRELIDE": 1.1810829962535547, "APREPITANT": 1.2087358197490263, "ARAVA": 1.0290055032003, "AVELUMAB": 1.062089177816329, "BREYANZI": 1.0156336269159263, "CABAZITAXEL": 1.0488272049688645, "CABOMETYX": 1.0367686047757705, "CAPSAICIN": 1.483564968753761, "CHLORHEXIDINE": 1.2016905608406303, "COMIRNATY": 2.5862572664641355, "COVID19": 3.042111429090786, "DASSELTA": 1.563089690786187, "DEGARELIX": 1.47200374240005, "ENZALUTAMIDE": 1.5295254989089997, "ESBRIET": 1.0360081701306751, "FABRAZYME": 1.1025118475384512, "FASLODEX": 1.037018822339145, "FLUCELVAX": 1.0902600184553577, "FOTIVDA": 1.6904454309735304, "IBRANCE": 1.5172812938803624, "INFERGEN": 1.451859423140739, "INLYTA": 1.0363269703099431, "ISTURISA": 1.0517858675188136, "JCOVDEN": 2.16431446568056, "KESIMPTA": 1.0850333874219815, "LONQUEX": 1.3165942191060145, "LONSURF": 1.480256858197021, "LYNPARZA": 1.1676902539428606, "MAVENCLAD": 1.3669397169201354, "NIMENRIX": 1.1223842903780343, "NUBEQA": 1.4799163585889323, "OCRELIZUMAB": 1.5085585018462389, "OLAPARIB": 1.468818509832187, "ONIVYDE": 1.2667613951604992, "ORGOVYX": 1.5911639942547402, "PEGASYS": 1.05151737542643, "REBLOZYL": 1.5218422891991896, "REMSIMA": 1.3525762971547362, "RUBRACA": 1.7692358239372885, "SPIKEVAX": 2.715820605658442, "STIRIPENTOL": 1.9994903675961568, "TOZINAMERAN": 1.7223629967955283, "TRODELVY": 1.4041073180021924, "VAXZEVRIA": 2.073003138679596, "VOTRIENT": 1.0655279076880744, "XTANDI": 1.877079927508387, "ZEPATIER": 1.240279872638459}
\ No newline at end of file
+{"JARDIANCE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3112.json
index 542a48bbfba..323cf7a8fcb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3112.json
@@ -1 +1 @@
-{"null": 1.915970905279455}
\ No newline at end of file
+{"ADALIMUMAB": 4.413621792166813, "ARAVA": 4.170074981818623, "SIMPONI": 18.75651802753144, "STELARA": 19.238357301427552, "VAXZEVRIA": 0.6173105140989283, "ZOSTAVAX": 21.66311555200149, "null": 0.2397294371994981}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3113.json
index 476044fcb9d..e167d8eceea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3113.json
@@ -1 +1 @@
-{"ABILIFY": 2.457177193388966, "AERIUS": 2.5483737387212764, "ANTIBIOTICS": 8.642087545705975, "ARIPIPRAZOLE": 1.2502275431721777, "ATRIPLA": 1.139380267341573, "BENLYSTA": 1.8277739334805785, "BRINTELLIX": 3.4336967375575886, "BRIVIACT": 4.423033777376481, "CHAMPIX": 6.443653022191827, "CYMBALTA": 2.494472681394164, "DABRAFENIB": 4.666537695235013, "DULOXETINE": 7.864310341636544, "EVISTA": 2.6348847814667944, "EXFORGE": 1.3288655683308217, "FASENRA": 1.0470822612746766, "FIRDAPSE": 2.305000881015459, "GALVUS": 2.968450015096424, "IBUPROFEN": 1.2554889823862736, "JANUMET": 1.2711165197840062, "KEPPRA": 1.5626881074283243, "LANTUS": 1.1351599551256264, "LATUDA": 7.643842398239859, "LEVETIRACETAM": 1.3991367116386844, "LYRICA": 2.716167522723849, "NUCALA": 1.1086197636187272, "OLANZAPINE": 1.846570717727964, "OMALIZUMAB": 1.4228718749328526, "RELVAR": 2.532557645150189, "SIFROL": 3.7696767035812018, "STRIBILD": 1.0693898438405316, "SUBOXONE": 1.9403577439133928, "TAMIFLU": 4.375754331430009, "TRUVADA": 1.20188802518762, "TWINRIX": 1.6742308985379704, "VIMPAT": 1.9720956653334083, "XOLAIR": 1.725805519110514, "ZYPREXA": 2.039911755356885, "null": 2.385596435484848}
\ No newline at end of file
+{"ABACAVIR": 16.890621327361735, "ABILIFY": 7.966214721580478, "ARAVA": 2.624500721923035, "ENBREL": 46.37452397507285, "null": 1.7696338523326471}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3114.json
index e4b2652f84c..d7f084c1160 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3114.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"OPTIMARK": 2286.1969330859497, "null": 0.4856701020197339}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3115.json
index a6763a9be09..8a0dd1aa53c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3115.json
@@ -1 +1 @@
-{"CHAMPIX": 2.224498456685196, "LANTUS": 1.1477467278135882, "null": 2.165824618148924}
\ No newline at end of file
+{"null": 5.838591260183384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3116.json
index 6dd2b037142..96d01983cd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3116.json
@@ -1 +1 @@
-{"null": 3.5531329557506397}
\ No newline at end of file
+{"null": 2.1811474582026085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3117.json
index cb27efd82fb..8cb0ecda927 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3117.json
@@ -1 +1 @@
-{"null": 1.0472260051202753}
\ No newline at end of file
+{"ABATACEPT": 5.203083807785207, "ABILIFY": 0.6913385280676113, "ACETAMINOPHEN": 13.452909459905571, "ACTOS": 1.3167929231160185, "ADALIMUMAB": 4.250706128528308, "ADCIRCA": 0.6163045364632003, "ADEMPAS": 0.9860195775137626, "ADVATE": 6.771531811078156, "AFINITOR": 0.5868095190244276, "AIMOVIG": 1.953841490598966, "ALEMTUZUMAB": 1.239375542887338, "ALISKIREN": 6.227433697802036, "AMINOSALICYLIC": 2.118331954108597, "ANAKINRA": 1.252845520417496, "APIDRA": 0.4570621754407242, "APIXABAN": 0.8963918860966944, "APREMILAST": 1.0382367372211327, "APREPITANT": 17.2122099043093, "ARANESP": 0.2402346603671408, "ARAVA": 3.2922468019153484, "AUBAGIO": 0.9865476374520832, "AVANDIA": 0.1068009389984093, "AZILECT": 1.6932787352881666, "BELIMUMAB": 1.622684542534421, "BENLYSTA": 1.067199760829853, "BETMIGA": 0.5623156816924547, "BEVACIZUMAB": 0.19589873884935, "BOSULIF": 0.361330473383726, "BRILIQUE": 7.244599654340114, "BRINTELLIX": 1.675012981578409, "BRIVIACT": 0.8606545840210165, "BRUKINSA": 9.074132003070314, "BUDESONIDE": 0.2947193403935034, "BUPIVACAINE": 0.3567605721923763, "BUPRENORPHINE": 0.1102627463806476, "BYDUREON": 1.851255870405572, "BYETTA": 0.3534291715938112, "CABOMETYX": 0.3748836169855108, "CAPECITABINE": 0.3180055569911675, "CELLCEPT": 0.2951841838198267, "CHAMPIX": 0.3770982998143475, "CHLORHEXIDINE": 6.856317590891874, "CICLOSPORIN": 0.3248871337092512, "CIMZIA": 3.855594909891202, "CINRYZE": 1.957989733228878, "CLOPIDOGREL": 2.4630811512057167, "COLLAGENASE": 32.22100194002236, "COMIRNATY": 0.6831746317524192, "COSENTYX": 1.4896837678852357, "CYMBALTA": 0.7551036287557682, "CYTARABINE": 0.3664649705842056, "DESCOVY": 0.9632626354230468, "DEXAMETHASONE": 0.5491800781119184, "DULOXETINE": 0.8331077074121277, "EFIENT": 2.8768384125875177, "ELIQUIS": 4.312874839844166, "ENBREL": 0.6429037661333062, "ENOXAPARIN": 1.355402310432895, "ENTECAVIR": 1.4998262359039731, "ENTRESTO": 0.4832420215971597, "ENTYVIO": 0.4885981242278008, "ERELZI": 2.4155333192929165, 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1.030148446008153, "JANUMET": 0.1538911795401825, "JANUVIA": 0.3210194188192671, "JARDIANCE": 0.1258953035825679, "KEPPRA": 0.4128432679474174, "KESIMPTA": 0.7931071090066264, "KEYTRUDA": 0.1019222909636865, "KOVALTRY": 7.802982581547032, "LAMIVUDINE": 0.5803031922906776, "LANTUS": 0.6166350240336609, "LATUDA": 0.3266599959869287, "LEFLUNOMIDE": 0.7968020343537761, "LEMTRADA": 2.2729604260654117, "LEVEMIR": 0.3200361605564842, "LEVOFLOXACIN": 0.339306942736891, "LIXIANA": 2.60595841247187, "LONSURF": 0.5686565063999351, "LYNPARZA": 0.3251045211844993, "LYRICA": 0.8312168034880696, "MAYZENT": 12.902804217982728, "MEKINIST": 0.1942890793245791, "MEMANTINE": 1.2964597334842227, "MEPOLIZUMAB": 0.9476587841430124, "METHOTREXATE": 2.432567195137984, "MICARDIS": 0.1782112665589699, "MMRVAXPRO": 0.1626829064847905, "MULTAQ": 0.5213189996605092, "MYCOPHENOLATE": 0.9017681331741924, "NAGLAZYME": 0.3972548069361579, "NEULASTA": 0.3978900535271757, "NEXAVAR": 0.2839208388309366, "NORVIR": 0.3800376145581716, "NOT": 0.5669836606642576, "NPLATE": 4.031802295293554, "NUCALA": 0.6010161185555288, "OCALIVA": 0.6099938783455859, "OCRELIZUMAB": 1.4688276282802075, "OFEV": 0.4956858222520562, "OLANZAPINE": 0.2303978479948001, "OMALIZUMAB": 1.725683212845487, "OPDIVO": 0.1101766508519295, "OPSUMIT": 0.5898987092191795, "PANTOPRAZOLE": 1.8499566064596675, "PEGASYS": 0.7247242209987333, "PEGINTERFERON": 0.1957362895287813, "PEGINTRON": 0.5617649669513048, "PLAVIX": 4.907930258025183, "PLEGRIDY": 1.184421734065687, "PRADAXA": 2.201419407419697, "PRASUGREL": 3.237816455384399, "PREGABALIN": 0.7243985393025847, "PROPRANOLOL": 0.6703124032735593, "REMICADE": 0.5240721034152844, "REVATIO": 0.801945865340352, "REVLIMID": 0.5966923399937055, "RINVOQ": 0.8762855235446894, "RITUXIMAB": 1.0403026280707544, "ROACTEMRA": 0.4986637721672101, "RUBRACA": 0.3277942369754551, "RUCONEST": 1.5127320949494707, "RUXOLITINIB": 0.8689573927090555, "SAXENDA": 0.3193985706170372, "SHINGRIX": 0.4100956756920302, "SIMPONI": 0.4932501499491105, "SOLIRIS": 0.6243905884013317, "SOMATROPIN": 3.217902387412193, "SPIKEVAX": 0.5410990139570594, "SPRYCEL": 0.6491720873374723, "STELARA": 0.5804483108497288, "SUBOXONE": 0.4847787632540004, "SUTENT": 0.8925028564712639, "TAGRISSO": 0.2935861948662492, "TAMIFLU": 0.4289024997447823, "TASIGNA": 0.3111331523444252, "TEDUGLUTIDE": 4.402898631708857, "TICAGRELOR": 1.814919985739668, "TOZINAMERAN": 1.2502848312281158, "TRACLEER": 0.2910122099799507, "TRELEGY": 0.3681907660981453, "TRULICITY": 0.1347243965492082, "TWINRIX": 0.4192499253168099, "VAXZEVRIA": 2.112941484076723, "VIAGRA": 0.2248678884085515, "VICTOZA": 0.2038600743395365, "VIMPAT": 0.8905117602396266, "VOTRIENT": 0.6992137411400235, "XARELTO": 2.970303125603756, "XELJANZ": 1.1423145838638202, "XOLAIR": 0.8676668510327231, "XTANDI": 0.4600004473433211, "XYREM": 0.5641614179899508, "ZOSTAVAX": 0.6371804088902734, "ZYPREXA": 0.3825354209868226, "null": 0.6811900565540799}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3118.json
index f781eb5001d..1c93d877847 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3118.json
@@ -1 +1 @@
-{"null": 1.3882316254496658}
\ No newline at end of file
+{"null": 1.174616373878293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3119.json
index ce10710be77..6accfd2fbd2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3119.json
@@ -1 +1 @@
-{"ABATACEPT": 12.054149175888003, "ADALIMUMAB": 8.085083176756944, "AIMOVIG": 6.181806712829599, "ARAVA": 1.816174728564972, "CICLOSPORIN": 6.778857227510716, "CIMZIA": 4.089456804164127, "COSENTYX": 6.984317907002021, "CYMBALTA": 3.275201566018774, "ENBREL": 11.73309678014015, "GARDASIL": 2.758993614797749, "LANTUS": 1.3885265125557311, "NUCALA": 16.948859976954825, "OMALIZUMAB": 6.058836619874021}
\ No newline at end of file
+{"CHAMPIX": 5.196758584192865, "COMIRNATY": 0.6214066844765117, "CYMBALTA": 3.050745048753865, "FENTANYL": 5.337964194949783, "GARDASIL": 21.537297112312565, "SPIKEVAX": 0.479452878308402, "TAMIFLU": 6.234781747084353, "TOZINAMERAN": 2.019462108444354, "VAXZEVRIA": 0.8824918336589516, "null": 1.1198700310039933}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/312.json
index b21021637fb..5283cfe9346 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/312.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/312.json
@@ -1 +1 @@
-{"null": 1.131855994377518}
\ No newline at end of file
+{"APIDRA": 0.5769786366632869, "COMIRNATY": 10.555401495208908, "HIZENTRA": 1.754394280349447, "HUMALOG": 0.5203633000076595, "MMRVAXPRO": 0.4871495206827116, "MODERNA": 0.8060691517385258, "NIMENRIX": 1.2193986651722204, "SPIKEVAX": 1.0895310067458504, "VAXZEVRIA": 2.6126580719740096, "null": 0.1603589772303849}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3120.json
index 2eaa598f27b..3524910608e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3120.json
@@ -1 +1 @@
-{"null": 1.53567740245871}
\ No newline at end of file
+{"null": 1.7675551134348293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3121.json
index 73eaafa816e..29a5e6ab167 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3121.json
@@ -1 +1 @@
-{"ATRIPLA": 29.39543780462354, "STRIBILD": 44.68238171689551, "TRUVADA": 18.65184844518581}
\ No newline at end of file
+{"COMIRNATY": 0.3080937149631775, "null": 5.898583373889248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3122.json
index 09249107e87..20c1a1b6954 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3122.json
@@ -1 +1 @@
-{"ALIMTA": 45.737569991035, "BINOCRIT": 95.85085367940256, "BUSILVEX": 74.02413595356012, "CYTARABINE": 16.05022267978736, "DEXAMETHASONE": 7.274988606907375, "DOXORUBICIN": 14.738893388231258, "EMEND": 80.07372076413918, "JEVTANA": 16.468389662816666, "KEYTRUDA": 4.057783651184814, "MABTHERA": 57.595154942346966, "METHOTREXATE": 8.05808736448486, "NEULASTA": 12.034519595265424, "PEMETREXED": 26.772052895399803, "TAXOTERE": 47.19696517020128, "TEMODAL": 61.73465827641543, "TRODELVY": 51.048881791699, "VFEND": 7.414685828411019}
\ No newline at end of file
+{"BUPRENORPHINE": 28.365090590396974, "KEPPRA": 32.525634297921414, "null": 1.7990739111788931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3123.json
index 905ee3c61de..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3123.json
@@ -1 +1 @@
-{"BEXSERO": 69.78941375597832, "HEXYON": 53.758907140888994, "INFANRIX": 81.01039778465645, "MENQUADFI": 44.19335513431783, "MENVEO": 4.8867043759076685, "MMRVAXPRO": 61.82734470855022, "NIMENRIX": 45.85029231307813, "NOT": 4.226643834834412, "POLIOMYELITIS": 218.51300411561223, "PREVENAR": 58.6699166913204, "PROQUAD": 81.93010160442066, "ROTARIX": 94.908314252122, "ROTATEQ": 4.864111002089184, "SYNAGIS": 4.456393200026168, "SYNFLORIX": 104.2446634797766, "TAMIFLU": 1.516165118519738, "TWINRIX": 1.8549079274607727, "VARICELLA": 276.5031654646899, "null": 3.360910891301883}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3124.json
index c780edad6e7..d6a28cbc676 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3124.json
@@ -1 +1 @@
-{"JARDIANCE": 8.271446706783479, "NAGLAZYME": 134.86324540865525, "NEULASTA": 18.51688409736594}
\ No newline at end of file
+{"HUMAN": 98.71477637316032, "PRIVIGEN": 210.2039263971237, "SOLIRIS": 13.324693482824175, "null": 2.1004546768146457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3125.json
index 1bbe15372ef..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3125.json
@@ -1 +1 @@
-{"ANAKINRA": 512.0796695649108}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3126.json
index 21af4fd462f..5c4b6e0bd41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3126.json
@@ -1 +1 @@
-{"ABRAXANE": 11.1327560184904, "ADCETRIS": 49.705165153382254, "ALEMTUZUMAB": 4.413969588305796, "ALIMTA": 11.926965603202683, "ALOXI": 7.775614210119801, "AMIKACIN": 2.0624746107322904, "ARZERRA": 4.572052119832367, "ASPARAGINASE": 23.878899281226914, "ATEZOLIZUMAB": 2.8218283362710674, "AVASTIN": 6.021737715764351, "AVELUMAB": 7.9766715281757135, "AXICABTAGENE": 7.587044907758247, "AZACITIDINE": 57.72506348179317, "BASILIXIMAB": 1.0735353583051763, "BEAM": 29.681723734005992, "BEVACIZUMAB": 7.777786918692331, "BLINATUMOMAB": 10.008951094035778, "BLINCYTO": 10.8561907412344, "BORTEZOMIB": 8.091478180854834, "BRENTUXIMAB": 22.86711427181714, "BUSILVEX": 11.183740004502177, "BUSULFAN": 18.71947842270012, "CABAZITAXEL": 19.070954794234314, "CAELYX": 8.438589942503333, "CANCIDAS": 3.305773377064434, "CAPECITABINE": 2.517304199184345, "CARFILZOMIB": 6.068337836788587, "CARMUSTINE": 36.17453827670129, "CASPOFUNGIN": 5.0771209293157264, "CELLCEPT": 1.731120678347957, "CETUXIMAB": 7.222634621859203, "CICLOSPORIN": 2.6003322856078728, "CLADRIBINE": 22.688508091551977, "CLOFARABINE": 21.71906540082924, "CRESEMBA": 9.188030188132352, "CYRAMZA": 33.47390484485422, "CYTARABINE": 45.81071324906084, "DACOGEN": 17.857217806011302, "DARATUMUMAB": 7.012886842356283, "DARUNAVIR": 1.5729330323138444, "DARZALEX": 4.633424286719122, "DASATINIB": 2.202481132585026, "DECITABINE": 22.974699239047236, "DEFITELIO": 3.649380583156115, "DENOSUMAB": 2.286582056362342, "DEXAMETHASONE": 11.238676483698516, "DEXRAZOXANE": 17.89241831710447, "DOCETAXEL": 28.6039918549468, "DOXORUBICIN": 33.866760707716715, "DURVALUMAB": 19.157564658482517, "EMEND": 1.948942866024692, "EPCORITAMAB": 16.946923541004338, "ERBITUX": 5.136998285102881, "ERIBULIN": 8.331747686386285, "ERLEADA": 1.442741094191144, "EXJADE": 1.024374958555707, "FASLODEX": 1.0090015303694928, "FILGRASTIM": 35.835060872544766, "FULVESTRANT": 1.9250541016356235, "GANCICLOVIR": 2.5514577489793666, "GAZYVARO": 3.821791946146434, "HALAVEN": 62.68894754290422, "HERCEPTIN": 7.358378751322185, "HYCAMTIN": 14.75578955889442, "IBRANCE": 2.5069781970912413, "IBRUTINIB": 6.777115586950506, "ICLUSIG": 2.08746355379326, "IMATINIB": 3.0719832743901807, "IMBRUVICA": 1.9202076315475016, "IMFINZI": 10.661499865196593, "IMNOVID": 5.969290767559164, "IRINOTECAN": 14.53730251034466, "JEVTANA": 85.26930555549139, "KEYTRUDA": 2.807997715164142, "KISQALI": 1.2827064746010364, "KYMRIAH": 3.787204974713673, "KYPROLIS": 4.2226366309294905, "LENALIDOMIDE": 12.201021266757577, "LONQUEX": 23.38206119690035, "LONSURF": 9.407784526088236, "LYNPARZA": 1.7343094093081972, "MABTHERA": 20.043343567149268, "MELPHALAN": 20.356831366201032, "MERCAPTOPURINE": 48.199582006460346, "METHOTREXATE": 5.939602253351101, "MIDOSTAURIN": 16.53198203611618, "MYCOPHENOLATE": 2.587618501224336, "NEULASTA": 38.821478619629374, "NIVESTIM": 6.590292384945143, "NIVOLUMAB": 4.432164173693639, "NOT": 2.598327012138187, "NOXAFIL": 4.697960667887392, "OBINUTUZUMAB": 15.055158129567705, "ONCASPAR": 11.620270303241446, "OPDIVO": 2.621422649534555, "PACLITAXEL": 8.317356022640972, "PALBOCICLIB": 7.63696506270799, "PANITUMUMAB": 10.10843594832608, "PAZOPANIB": 1.1511519084985635, "PEGASPARGASE": 15.743999083044455, "PEGFILGRASTIM": 49.12868073982738, "PEMBROLIZUMAB": 3.438972151551652, "PEMETREXED": 9.213016454774568, "PERJETA": 4.567332124354529, "PERTUZUMAB": 17.226346395835417, "POLATUZUMAB": 12.957173569799156, "POMALIDOMIDE": 10.36837363089763, "POSACONAZOLE": 2.3914653118216247, "REVLIMID": 2.7190525650161788, "RIBOCICLIB": 2.6518169682372834, "RITUXIMAB": 16.070047843491135, "RYDAPT": 11.25544469682487, "SACITUZUMAB": 7.74948614293307, "SORAFENIB": 1.2855283780263151, "SPRYCEL": 1.099513266280756, "TACROLIMUS": 1.243912660343028, "TAXOTERE": 10.331509711212863, "TEGAFUR": 2.600021384872554, "TEMODAL": 4.230445632688407, "TEMOZOLOMIDE": 5.276576310830276, "TEMSIROLIMUS": 29.09691853793297, "THALIDOMIDE": 3.443644831636957, "THERAPEUTIC": 17.563989664438253, "THIOTEPA": 20.523005794198767, "TISAGENLECLEUCEL": 13.811249080970205, "TOPOTECAN": 80.62188377634364, "TORISEL": 2.395941843603665, "TRABECTEDIN": 10.616668020940304, "TRASTUZUMAB": 26.77580130996868, "TRISENOX": 3.919462467594223, "TRODELVY": 21.01203460348041, "VECTIBIX": 3.869850089455552, "VELCADE": 5.169660030664931, "VENCLYXTO": 7.490228400116724, "VENETOCLAX": 26.213232806241308, "VIDAZA": 22.154718997422755, "VORICONAZOLE": 1.593586586367398, "VYXEOS": 55.21249773350638, "XELODA": 4.032253310476976, "YESCARTA": 6.44990512549063, "YONDELIS": 11.031648660353635, "ZARZIO": 11.730560245907713}
\ No newline at end of file
+{"DARZALEX": 586.978795038228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3127.json
index 75ee35aa51a..5676f7591e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3127.json
@@ -1 +1 @@
-{"HUMAN": 82.12769403328932, "PRIVIGEN": 317.7727198394914, "null": 2.5266024138001204}
\ No newline at end of file
+{"null": 1.4923989230855297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3128.json
index f75830a4ad1..a00be45de71 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3128.json
@@ -1 +1 @@
-{"ACETYLSALICYLIC": 81.33244164644749, "AFINITOR": 5.230621270443996, "AMBRISENTAN": 6.791424561786785, "APIDRA": 2.200481598379397, "AUBAGIO": 1.26147158850258, "BENLYSTA": 1.813597020208197, "BOSULIF": 3.0241784931202704, "BRAFTOVI": 3.285153783662985, "CABOMETYX": 1.4545866582064082, "CIMZIA": 1.3794484570856913, "CLOPIDOGREL": 1.3261071872846564, "COSENTYX": 1.0339271009973183, "DULOXETINE": 1.0854814474657708, "ESBRIET": 2.587783881382597, "FASLODEX": 1.1715665878433197, "FIRDAPSE": 3.548973781086381, "FORSTEO": 2.338893675408068, "FULVESTRANT": 2.369856892883748, "HARVONI": 1.4691320698760717, "HUMALOG": 2.239621408551056, "IBRANCE": 2.907722490687205, "INLYTA": 4.713536244005971, "IRESSA": 1.5577270224193558, "JANUMET": 1.0731402455162389, "JARDIANCE": 1.138768789671266, "KEPPRA": 1.6849890367322244, "KEYTRUDA": 2.406936131048468, "LONSURF": 2.7428534297056557, "LYNPARZA": 2.3689014331112577, "MEKINIST": 1.3830748590295123, "MELATONIN": 3.120403623431516, "MEPOLIZUMAB": 5.228702119655191, "NEULASTA": 1.1106874533600424, "NEXAVAR": 1.267091223151776, "OFEV": 1.4485797735974868, "PANTOPRAZOLE": 1.1284447343580168, "PEGASYS": 1.2676870072075406, "PEGINTRON": 2.0230253038636388, "ROTATEQ": 1.3082214269973922, "RYBELSUS": 2.9923371106013543, "SAXENDA": 1.8908165738510696, "SPINRAZA": 1.9502110327793871, "STALEVO": 2.8815379729520307, "STIVARGA": 1.602241535919579, "SUTENT": 6.7665132466120825, "SYNAGIS": 4.40225001172453, "TAGRISSO": 3.094787333093971, "TEDUGLUTIDE": 22.985848965815062, "TOZINAMERAN": 1.6400295368024822, "TRELEGY": 1.1327818203664193, "TRULICITY": 10.424494113627816, "VFEND": 1.1018564740997707, "VOTRIENT": 2.011874490830634, "XALKORI": 3.2814206874155505, "XTANDI": 2.511557472977726}
\ No newline at end of file
+{"AZATHIOPRINE": 76.25354625343742, "BUSULFAN": 22.02783973129844, "CICLOSPORIN": 25.718570831295985, "PEGINTRON": 11.21888842208301, "null": 1.180782239849031}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3129.json
index 98a0d17c584..7e5a629f4d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3129.json
@@ -1 +1 @@
-{"null": 1.0414314976561247}
\ No newline at end of file
+{"SOLIRIS": 36.2909655248785, "null": 1.389621825415113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/313.json
index c88e5c16728..4af74925ee3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/313.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/313.json
@@ -1 +1 @@
-{"DOCETAXEL": 16.121330373829316, "PEGASYS": 3.1805242980303534, "PEGINTERFERON": 24.299120254590505}
\ No newline at end of file
+{"COMIRNATY": 3.6425063876375896, "null": 0.489587685703479}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3130.json
index 9d060337a07..4a16453b3c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3130.json
@@ -1 +1 @@
-{"null": 1.099498120056937}
\ No newline at end of file
+{"ABILIFY": 1.4188693335413374, "ALISKIREN": 108.306727598702, "ANAKINRA": 2.3654530133217557, "ARIPIPRAZOLE": 2.877926460193663, "AUBAGIO": 1.754740126084122, "BRINTELLIX": 0.6696251028012988, "BUDESONIDE": 0.4726009398825758, "BUPIVACAINE": 2.0784387384691416, "CHAMPIX": 3.986987174558451, "CLOPIDOGREL": 0.2824093882976688, "COMIRNATY": 0.7033726606598256, "CYMBALTA": 2.0034336489402227, "ELIQUIS": 0.2593845134790428, "FAMPYRA": 1.423771956066995, "FASLODEX": 0.8926870969645444, "FENTANYL": 0.7395331317770375, "GARDASIL": 1.4517614744821865, "IBRANCE": 0.2467033136246046, "IRBESARTAN": 2.2069641789403747, "KALETRA": 1.5050720664160608, "KEPPRA": 3.721878886209749, "LANTUS": 0.7688370540358509, "LATUDA": 1.1825413762293329, "LEMTRADA": 1.326340037922777, "LEVETIRACETAM": 3.885656072407611, "LEVOFLOXACIN": 1.2655217780065782, "LYRICA": 1.7669955547654743, "MELATONIN": 3.959863966550817, "MIDAZOLAM": 1.9390170081196616, "OLANZAPINE": 1.3569989109837055, "PEGASYS": 0.7754705344934884, "PEGINTRON": 0.5808607204881531, "PLAVIX": 0.5901191231559558, "SPIKEVAX": 0.507144906662004, "STALEVO": 2.886576406507133, "SUTENT": 0.3139836298972487, "TAMIFLU": 1.435125208069091, "TOZINAMERAN": 0.9476970587299454, "TWINRIX": 3.5286366255105928, "VAXZEVRIA": 0.6024060684340841, "VIMPAT": 6.827824129920297, "ZOSTAVAX": 0.5911335869060098, "ZYPADHERA": 5.333590560366172, "ZYPREXA": 0.9706915575150566, "null": 1.9952819146790344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3131.json
index 93e51c259ac..6be5580992a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3131.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.0872196196020334, "ABILIFY": 1.48457496190923, "ACE": 5.182182794801889, "ADCIRCA": 2.024008910818581, "ADEMPAS": 1.3495748702063983, "AIMOVIG": 1.6283216017257949, "AMBRISENTAN": 2.374010380050143, "ANAKINRA": 2.216047695579872, "APIDRA": 1.9554950265237088, "APIXABAN": 2.51854014652162, "AUBAGIO": 1.2141768247919684, "AVONEX": 1.5091940978334526, "BENLYSTA": 1.7004093733771408, "BETMIGA": 1.243327953492186, "BEXTRA": 4.6862804188714735, "BOSULIF": 1.0588932180703798, "BRINTELLIX": 3.724847140827564, "BRIVIACT": 2.2386485032631054, "BUPRENORPHINE": 1.1023820209474613, "BYDUREON": 1.9308303588763296, "CARBIDOPA": 1.581875021774778, "CHAMPIX": 4.620922660865727, "CIRCADIN": 1.4934744515144895, "CLOPIDOGREL": 1.3369498553927237, "COMTAN": 2.1098250111916577, "COSENTYX": 1.1263535196633323, "CYMBALTA": 2.689952261451072, "DIFICLIR": 1.389587664613585, "DUKORAL": 4.188819983194419, "DULAGLUTIDE": 1.5450527125335909, "DUPIXENT": 1.5655114012577953, "ENBREL": 1.161926194823565, "ENTACAPONE": 1.1541573265290157, "ENTRESTO": 2.097388170792456, "ETANERCEPT": 1.457233298119899, "EVENITY": 1.034742385524979, "EVISTA": 1.2728567163466822, "EXCELASE": 20.667155510802168, "EXFORGE": 3.173329836213496, "FAMPYRA": 2.1518066792860533, "FASENRA": 1.2415312320550558, "FENTANYL": 1.0878260032003766, "FIRDAPSE": 2.816316161144514, "FLUCELVAX": 1.890981387782327, "FORSTEO": 1.997441648048485, "FULVESTRANT": 1.119889997171376, "FYCOMPA": 1.4891235838240695, "GALAFOLD": 1.1576530134772285, "GALVUS": 1.149182710728596, "GENVOYA": 1.109704793336664, "HUMALOG": 2.0173551651203496, "IBRANCE": 1.8065311846690184, "INCRUSE": 1.3957595228552886, "INLYTA": 1.0486194142293748, "INSULIN": 1.098424130834352, "INTERFERON": 1.0142806299117637, "INVEGA": 1.260992682991778, "IRON": 1.113760558482978, "KAFTRIO": 1.3512244096750587, "KEPPRA": 1.415767747938851, "KESIMPTA": 1.6642112600270214, "LANTUS": 2.016214862631184, "LATUDA": 4.795505277579212, "LEFLUNOMIDE": 1.4540649088037925, "LURASIDONE": 1.2207205431424188, "LYRICA": 3.7713802151917264, "MELATONIN": 3.2642761857077045, "MIRABEGRON": 1.6831661969279403, "MIRCERA": 1.05378210522363, "MULTAQ": 1.2507338164094437, "NEULASTA": 1.7326855007287396, "NEUPRO": 3.0965184283149387, "OCRELIZUMAB": 4.286433740276772, "OMALIZUMAB": 1.6599760948254472, "OPSUMIT": 1.2904341783779008, "ORENCIA": 1.6435331804061584, "OZEMPIC": 2.199208541136342, "PAXLOVID": 2.7775552601216478, "PIRFENIDONE": 1.495692991978594, "PLEGRIDY": 1.886501470058484, "POPPERS": 6.677080769786594, "PRIALT": 3.3862928186652064, "PROLIA": 1.1606253470340089, "RASILEZ": 1.761623846359469, "REBIF": 1.8697547828349896, "RELVAR": 1.319758333836624, "REVATIO": 1.118704395113167, "RISPERIDONE": 3.492269262438848, "SEMAGLUTIDE": 3.0819472255478364, "SHINGRIX": 1.415244446879963, "STALEVO": 1.959968473149496, "SUBOXONE": 2.818154086039913, "SUTENT": 1.5463851803149502, "TEDUGLUTIDE": 5.367405670299214, "TOUJEO": 2.199732907308825, "TOVIAZ": 2.07285555392757, "TOZINAMERAN": 2.276074056105211, "TRELEGY": 1.0744837648638297, "TRULICITY": 1.3993244357038217, "UNSPECIFIED": 1.90993366801983, "VARENICLINE": 1.0143294302535766, "VELTASSA": 1.0467898283889048, "VIAGRA": 1.3266340991270589, "VIMPAT": 1.4161117478999057, "XELJANZ": 1.379649696390848, "XOLAIR": 1.3739761513156297, "XTANDI": 1.440359013874247, "XYREM": 4.958327086551993, "ZYPADHERA": 1.898428929300875, "ZYPREXA": 1.0647383656991367, "null": 1.273260806436997}
\ No newline at end of file
+{"null": 2.5976518060301648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3132.json
index 938e51bd9c4..f36e6028fd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3132.json
@@ -1 +1 @@
-{"ACLASTA": 3.069383043430526, "ADCIRCA": 1.7325842154977042, "AMBRISENTAN": 1.1201921707542308, "COMIRNATY": 1.7476678058091075, "COVID19": 5.273478989088326, "EDOXABAN": 6.599960339346205, "ELLAONE": 1.360883030988104, "FIRDAPSE": 2.938477271034456, "FLEBOGAMMA": 8.577465019364762, "FORSTEO": 1.033708046813737, "GARDASIL": 1.2032233557047494, "HYDROCORTISONE": 1.7839015380788832, "KESIMPTA": 1.9594674085924828, "KIOVIG": 3.387153975982057, "LEVODOPA": 1.290447701128553, "NIMENRIX": 1.2961235217522336, "PLEGRIDY": 1.089806668714334, "PREGABALIN": 1.0035428503412982, "PRIVIGEN": 2.475796150970327, "SHINGRIX": 1.7580953532231531, "SPIKEVAX": 1.7772113986121827, "TOZINAMERAN": 2.218611518280556, "VAXZEVRIA": 3.4955518953651383}
\ No newline at end of file
+{"AMINOSALICYLIC": 11.711072825290394, "AVANDIA": 24.225855822519204, "BEDAQUILINE": 114.79615156336146, "COMIRNATY": 0.1791431546436169, "OPSUMIT": 8.721198456179524, "REVATIO": 31.9503028950882, "TRACLEER": 75.32183481054007, "null": 0.8951283415029915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3133.json
index af831ddabfc..4432d6f1870 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3133.json
@@ -1 +1 @@
-{"BRINTELLIX": 3.1518764079806614, "CHAMPIX": 3.878582112330203, "CYMBALTA": 1.7663674408996943, "FORSTEO": 1.3754843046499403, "KEPPRA": 3.227438883213051, "LYRICA": 6.431967538926984, "PREGABALIN": 3.09232147334965, "TOZINAMERAN": 1.5545228653673877, "VIMPAT": 3.626686513189072, "XYREM": 9.496381190061712, "ZYPADHERA": 23.81473364229841, "ZYPREXA": 1.9705630615999392, "null": 1.77649160531225}
\ No newline at end of file
+{"COMIRNATY": 0.5508810869129921, "VAXZEVRIA": 0.7572775411911598, "null": 0.5442174385025228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3134.json
index 7e9c6ea97e5..ceb6113e538 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3134.json
@@ -1 +1 @@
-{"ABILIFY": 10.543807530742638, "ARIPIPRAZOLE": 9.991956928369166, "CHAMPIX": 7.449904340325764, "DULOXETINE": 19.147208611134143, "OLANZAPINE": 13.111634603880336, "SUBOXONE": 12.73339407539762, "null": 1.9114108597367283}
\ No newline at end of file
+{"null": 0.5979397031702495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3135.json
index e64d384c661..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3135.json
@@ -1 +1 @@
-{"AIMOVIG": 1.0969825652487848, "CABOTEGRAVIR": 2.3422892230098125, "CAELYX": 2.12627571503587, "COMIRNATY": 2.713598352262641, "COVID19": 1.3258806397139835, "DESLORATADINE": 1.1927084958722949, "EMEND": 1.4196423410860195, "FLEBOGAMMA": 2.224037535126375, "FLUCELVAX": 2.115844783564018, "GAZYVARO": 1.0288551902951544, "JCOVDEN": 4.440165533056033, "KIOVIG": 1.378494388532437, "LEMTRADA": 1.2042353487212616, "MENVEO": 1.757856042277869, "MIRCERA": 3.396729513191999, "MIRVASO": 9.760374108496348, "NIMENRIX": 1.4005894742790674, "OCRELIZUMAB": 1.2056833635869564, "PANTOPRAZOLE": 1.349356788765759, "PERJETA": 1.0403332027763617, "QUTENZA": 4.250103619096478, "RIXATHON": 2.8585958553710897, "SHINGRIX": 1.7751003553808575, "SPIKEVAX": 3.1717920327818945, "TOZINAMERAN": 2.1071363003896453, "TWINRIX": 1.2668994759257073, "VAXZEVRIA": 2.6420538197061214, "VIAGRA": 1.1093074803370897, "ZARZIO": 1.813191045439557}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3136.json
index 1b13248c7eb..1d979d302bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3136.json
@@ -1 +1 @@
-{"AIMOVIG": 1.013761479486914, "ATAZANAVIR": 8.568371140194829, "BYDUREON": 2.5533641259696696, "BYETTA": 4.095411907402606, "CELECOXIB": 10.70415470702378, "CHAMPIX": 1.537711238864055, "CYMBALTA": 2.266244409233728, "DEXAMETHASONE": 1.3352172921286656, "JANUMET": 1.269387611301436, "LATUDA": 4.893955864089135, "OLANZAPINE": 1.385769597161948, "SUBOXONE": 2.551363903372269, "XTANDI": 1.651195942958103, "XYREM": 23.63650974650078, "null": 2.254664772833481}
\ No newline at end of file
+{"null": 3.015891500848607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3137.json
index 7b5cbea5533..12a94b8b227 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3137.json
@@ -1 +1 @@
-{"COMIRNATY": 2.197930317318467, "COVID19": 4.0782337138209375, "ESOMEPRAZOLE": 2.530023739496978, "GARDASIL": 1.7261195829621807, "NIMENRIX": 2.3880433608597538, "SPIKEVAX": 1.894603210272679, "SUBOXONE": 5.806415910841904, "TOZINAMERAN": 3.958156170853539, "VAXZEVRIA": 2.359910113607084}
\ No newline at end of file
+{"BENLYSTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3138.json
index dac1d4f7fca..6b2b9d485d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3138.json
@@ -1 +1 @@
-{"ABILIFY": 4.05434602716916, "BRINTELLIX": 6.254906620698407, "CHAMPIX": 10.6610848793209, "CIALIS": 34.36296800537022, "CYMBALTA": 4.166807949135412, "FAMPYRA": 5.1822022962809, "HUMIRA": 2.5193538712117736, "LATUDA": 10.379118698451762, "LEVETIRACETAM": 2.139695809851041, "PEGASYS": 1.0775117859063037, "SUBOXONE": 2.1918392229118457, "VAXZEVRIA": 1.1164188550906098, "ZYPREXA": 1.5766196217330264, "null": 1.733631179888758}
\ No newline at end of file
+{"null": 2.234965918179927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3139.json
index b4f0c731499..3f2453243c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3139.json
@@ -1 +1 @@
-{"CHAMPIX": 11.54939764678119, "POPPERS": 8195.362592278176, "PTC": 6189.007009624309, "null": 1.1536756498689862}
\ No newline at end of file
+{"EYLEA": 79.21810259243514, "ZOSTAVAX": 12.484235456965488, "null": 2.1911936543916246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/314.json
index f3c09469c2d..bf67e53c9cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/314.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/314.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2482921175860782, "PEGINTERFERON": 86.02430164649437, "PEGINTRON": 9.122425473278778}
\ No newline at end of file
+{"null": 3.7738708059543176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3140.json
index d620494ece4..41651713749 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3140.json
@@ -1 +1 @@
-{"CHAMPIX": 8.168554746748166, "null": 3.484395605044972}
\ No newline at end of file
+{"null": 0.9124907343506812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3141.json
index 1e55ea35753..b8832d28d10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3141.json
@@ -1 +1 @@
-{"SIMPONI": 72.97621337365652}
\ No newline at end of file
+{"COMIRNATY": 0.9321873061151504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3142.json
index 30bb0c6acbb..4061401dd7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3142.json
@@ -1 +1 @@
-{"ADALIMUMAB": 23.6873120117876, "ALIGN": 297.0486247413064, "AMINOSALICYLIC": 169.4551418725758, "AVAMYS": 85.7733474093521, "AVASTIN": 6.288492714169968, "BUDESONIDE": 137.99235345300835, "ENTYVIO": 2.098364443008101, "KEYTRUDA": 2.490971027051593, "LENVIMA": 4.233363004187082, "PREGABALIN": 45.77806559339229, "STELARA": 1.9019762552865336}
\ No newline at end of file
+{"null": 1.9146015139537076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3143.json
index 654920763ad..e26ca121dd2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3143.json
@@ -1 +1 @@
-{"null": 3.571431063313624}
\ No newline at end of file
+{"null": 0.882049050778564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3144.json
index 534e829d0ab..700a68daac5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3144.json
@@ -1 +1 @@
-{"JARDIANCE": 30.957818849805463}
\ No newline at end of file
+{"null": 2.3225705684559967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3145.json
index 7328a2e7554..29cda579ae1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3145.json
@@ -1 +1 @@
-{"null": 1.690422363166397}
\ No newline at end of file
+{"EYLEA": 17.64183311629418, "null": 6.313311492874267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3146.json
index 8bb7c050e0b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3146.json
@@ -1 +1 @@
-{"null": 3.3921150717170643}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3147.json
index badb0102271..2ce58227953 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3147.json
@@ -1 +1 @@
-{"IBUPROFEN": 49.60117970772164}
\ No newline at end of file
+{"BEOVU": 29.88471962685086, "COMIRNATY": 0.0805434306031008, "DEXAMETHASONE": 8.726744751753595, "ELIQUIS": 1.1546418481839746, "EYLEA": 27.68209004360984, "JETREA": 102.31673199909172, "LANTUS": 2.036614968256369, "NEVANAC": 192.1726580425674, "PEGASYS": 1.1244706611903883, "null": 2.703687841464748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3148.json
index 7efa8018aa3..f00d5215d7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3148.json
@@ -1 +1 @@
-{"null": 3.5148518229747605}
\ No newline at end of file
+{"ZOSTAVAX": 18.03195716511369, "null": 1.3121169570308695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3149.json
index 7501880db64..b28cc5c4981 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3149.json
@@ -1 +1 @@
-{"null": 2.3465532070172253}
\ No newline at end of file
+{"null": 1.0697945780850726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/315.json
index 1429ecd06bc..10796662c93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/315.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/315.json
@@ -1 +1 @@
-{"COMBIVIR": 229.0867695823449, "NEXAVAR": 70.07344786311162}
\ No newline at end of file
+{"COMIRNATY": 1.624579235408086, "SPIKEVAX": 2.0238251489453227, "VAXZEVRIA": 0.4543016408053308, "null": 0.7963375639701694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3150.json
index 19c062499ae..85484037e76 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3150.json
@@ -1 +1 @@
-{"null": 2.387804269380746}
\ No newline at end of file
+{"EYLEA": 29.884750849975287, "NEPAFENAC": 3128.8831920553766, "NEVANAC": 369.58054074730455, "null": 3.02575663551684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3151.json
index 7466bb08304..6f1269344c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3151.json
@@ -1 +1 @@
-{"ATRIPLA": 3.934697545049544, "BONVIVA": 21.062285191614023, "CLOPIDOGREL": 1.303055144534263, "CYMBALTA": 1.312520371863226, "DEXAMETHASONE": 1.6443104971356135, "ELIQUIS": 2.570256929898922, "EVENITY": 109.3183785369566, "EVISTA": 8.441538707210738, "FORSTEO": 32.40047420047031, "HEPSERA": 48.62599775848373, "LIXIANA": 6.819362956609835, "OPSUMIT": 1.88371984048714, "TRUVADA": 2.394447525081536, "ZYPREXA": 1.2699556680249782}
\ No newline at end of file
+{"null": 2.943092615310143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3152.json
index b68999a6d67..779c3f54a2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3152.json
@@ -1 +1 @@
-{"null": 4.743659412034792}
\ No newline at end of file
+{"COMIRNATY": 0.8539576288533838, "SPIKEVAX": 1.0649941684134288, "TOZINAMERAN": 3.259428357113452, "VAXZEVRIA": 1.094538953051739, "null": 0.2896754223366112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3153.json
index 4e0e08e7651..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3153.json
@@ -1 +1 @@
-{"ABATACEPT": 1.4185660057110832, "ADALIMUMAB": 1.4667537030099858, "APIDRA": 1.5069122906952068, "ATRIPLA": 4.912562207644121, "BONVIVA": 53.23844721348703, "CELECOXIB": 6.088412729507736, "COAPROVEL": 2.3228316756815297, "ELIQUIS": 2.068177423261455, "ENBREL": 5.1506064497910975, "EVENITY": 55.55938056204546, "EVISTA": 18.87786805348156, "FASLODEX": 2.961305766318348, "FORSTEO": 19.008392016031515, "FORXIGA": 1.0171041416691498, "GALVUS": 4.537199751920985, "HEPSERA": 5.182428961977306, "HIZENTRA": 1.1052531042993048, "HUMALOG": 2.505115008597845, "IBRANCE": 2.66246101688211, "INLYTA": 1.1030410482313546, "JAKAVI": 1.5882063853638042, "JARDIANCE": 1.067019283752341, "KALETRA": 1.708815558710553, "LANTUS": 2.0665955736795665, "LYRICA": 1.00244659994285, "METHOTREXATE": 1.292911134403164, "OPSUMIT": 1.2501703320948476, "PROLIA": 15.044543227503732, "REVATIO": 1.35510644982882, "RINVOQ": 1.155823320923839, "RITUXIMAB": 1.2455941503647268, "SIMPONI": 2.976877091375123, "SPINRAZA": 16.382098824429015, "STALEVO": 3.138210888517888, "STRIBILD": 4.241734620439612, "SUBOXONE": 1.2986324894248746, "SUTENT": 1.2628444908206895, "TAGRISSO": 2.416476449857122, "TENOFOVIR": 9.745262188288708, "TERIPARATIDE": 16.10478800098519, "TRELEGY": 1.0398403111418526, "TRUVADA": 4.541301329245099, "VIREAD": 5.714946019178719, "XELJANZ": 3.299674382000317, "XOFIGO": 3.916114511767302, "XTANDI": 2.133065772637197, "null": 1.014717898099751}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3154.json
index cbdf69f4852..04b7e0c938e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3154.json
@@ -1 +1 @@
-{"SUBOXONE": 41.47779598071291, "null": 1.0245925900438484}
\ No newline at end of file
+{"null": 1.1619192809764267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3155.json
index 3e395d419a1..320f0019e5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3155.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 281.83310809847814}
\ No newline at end of file
+{"DEXAMETHASONE": 17.6597211971491, "NEVANAC": 407.96652397015856, "null": 2.5069013435605045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3156.json
index d909818c2d1..1c93d877847 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3156.json
@@ -1 +1 @@
-{"COVID19": 1.1932372216381886, "SPIKEVAX": 12.58163461267607, "VAXZEVRIA": 2.706868407105405}
\ No newline at end of file
+{"null": 1.174616373878293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3157.json
index 7cb384cd661..28fa1da37c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3157.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 1.061306097644284, "COMIRNATY": 2.799785467472632, "COVID19": 3.792462431233144, "ELIQUIS": 1.6809538155291424, "ENOXAPARIN": 3.775207167039533, "FENTANYL": 2.531645014641277, "KYMRIAH": 5.915109796147887, "LEMTRADA": 1.7091273270055831, "MEKINIST": 1.7260629781772294, "OPDIVO": 1.3908158973957443, "RINVOQ": 1.667006183234028, "SOLIRIS": 1.241266277622533, "SPIKEVAX": 1.057050126858279, "STIVARGA": 1.482666215303418, "TOZINAMERAN": 1.2089517840408992, "VAXZEVRIA": 3.8280514111739983}
\ No newline at end of file
+{"null": 1.6956901219911291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3158.json
index 901918c1868..3df553fb8e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3158.json
@@ -1 +1 @@
-{"null": 2.0373250893473926}
\ No newline at end of file
+{"null": 1.4869856224624525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3159.json
index ac4a2490d5f..f2d82726931 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3159.json
@@ -1 +1 @@
-{"null": 1.1894899744046088}
\ No newline at end of file
+{"AZOPT": 96.09666368828076, "BEOVU": 45.77809101844687, "BIMATOPROST": 572.2240041111621, "DEXAMETHASONE": 6.258019797951771, "EYLEA": 86.30894206872341, "LEVOFLOXACIN": 4.427213333271884, "NEVANAC": 248.803231333354, "ZOSTAVAX": 1.8549056034456664, "null": 3.537188420883071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/316.json
index 900544a7389..9e93b08fd40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/316.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/316.json
@@ -1 +1 @@
-{"COMBIVIR": 21.752127181864463, "HARVONI": 16.875268978623797, "NEXAVAR": 262.19548775766816, "PEGASYS": 10.339133414728591, "SORAFENIB": 117.58745308698218, "STIVARGA": 8.002770564380778}
\ No newline at end of file
+{"COMIRNATY": 0.3727656490145896, "SPIKEVAX": 2.7510707571721262, "null": 1.1321754003533908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3160.json
index bbbfcfe34a6..4d8845ef278 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3160.json
@@ -1 +1 @@
-{"MIDAZOLAM": 231.08493038647677}
\ No newline at end of file
+{"COMBIVIR": 15.354564899313944, "COMIRNATY": 0.1274579218067676, "EYLEA": 22.831353199241736, "LUMIGAN": 533.1505615899403, "NAGLAZYME": 123.44992596131256, "NEVANAC": 236.5319627352152, "TOBRAMYCIN": 50.27483862616008, "ZOSTAVAX": 6.069175903406945, "null": 2.746351409460498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3161.json
index 764efea534b..030666f2ec4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3161.json
@@ -1 +1 @@
-{"null": 1.57529124026637}
\ No newline at end of file
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3162.json
index b3a3b728e96..ea05b345b3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3162.json
@@ -1 +1 @@
-{"CICLOSPORIN": 34.306180628015696, "CYMBALTA": 5.000217046436411, "GARDASIL": 6.6079039566281255, "KEPPRA": 5.975838529198811}
\ No newline at end of file
+{"DEXAMETHASONE": 13.420941394086444, "LEVOFLOXACIN": 15.13815318750506, "NEVANAC": 284.4957059669732, "VORICONAZOLE": 45.04785603545755, "null": 1.84504726384007}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3163.json
index 05a64861594..c3b66daa00f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3163.json
@@ -1 +1 @@
-{"ZOSTAVAX": 10.297957616739248, "null": 3.08188442077795}
\ No newline at end of file
+{"null": 2.1690594457872248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3164.json
index baebea13d2c..8e9c35b8eec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3164.json
@@ -1 +1 @@
-{"null": 2.059191488784373}
\ No newline at end of file
+{"COMTAN": 163.64007628756076, "TOZINAMERAN": 2.367378678169929, "null": 1.134249464815445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3165.json
index ad9a8d855c5..07e795eb4c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3165.json
@@ -1 +1 @@
-{"null": 1.4012002052499064}
\ No newline at end of file
+{"ZOSTAVAX": 44.55821107520433, "null": 1.4084541007688185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3166.json
index f0154953547..7ae1c99f27e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3166.json
@@ -1 +1 @@
-{"ABATACEPT": 13.873957033250612, "ACLASTA": 11.566126105421327, "ADALIMUMAB": 19.820756048712404, "APIXABAN": 30.23298987729095, "APREMILAST": 12.549137230118596, "APREPITANT": 1.6472001611946134, "ARAVA": 4.219813130426774, "AVONEX": 6.382653422141187, "BENLYSTA": 2.4156415864492544, "BYDUREON": 1.7831544550045515, "CANNABIDIOL": 8.89091662842922, "CELECOXIB": 5.942398000589662, "CIMZIA": 2.2966668644952866, "CLOPIDOGREL": 4.020542991004923, "COSENTYX": 2.4855993938368783, "CYMBALTA": 3.344752951781586, "DULOXETINE": 1.925859392918169, "ELIQUIS": 1.1043358669791656, "ENBREL": 5.443243808640176, "ERENUMAB": 4.311736226389039, "ESOMEPRAZOLE": 2.508346861358289, "GARDASIL": 3.5640499589806574, "HUMIRA": 5.479513820979863, "HYDROCORTISONE": 1.2753266371084433, "LEFLUNOMIDE": 2.7841927450300004, "LYRICA": 6.984072770589046, "METHOTREXATE": 5.409520646046038, "MYCOPHENOLATE": 2.1538809714135656, "OMALIZUMAB": 1.3412361269368, "RITUXIMAB": 2.2365918639676705, "SIMPONI": 1.6334451985691942, "XELJANZ": 2.388502466328929, "XYREM": 6.786034529679121, "ZOSTAVAX": 2.2916462378410563}
\ No newline at end of file
+{"null": 1.6892141769044025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3167.json
index 2046b8fa8dd..afe53dc7fba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3167.json
@@ -1 +1 @@
-{"APTIVUS": 124.22201749932825, "ARIPIPRAZOLE": 4.04249192681621, "CARFILZOMIB": 19.57872538891105, "CICLOSPORIN": 1.57134179241492, "CONTRAST": 70.83132362950919, "ESBRIET": 6.724899520768648, "ETANERCEPT": 46.537228323332975, "EXJADE": 2.731191176654721, "EXVIERA": 27.12601783360264, "JAKAVI": 6.99209824927695, "NPLATE": 8.887544667574392, "OPTIMARK": 289.6170777983042, "PEGASYS": 2.5639962661187194}
\ No newline at end of file
+{"NEVANAC": 883.7926876336411, "null": 1.3973989127092554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3168.json
index 1ffebc51a08..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3168.json
@@ -1 +1 @@
-{"null": 1.359417735449565}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3169.json
index b2fae930e5b..79791e01c37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3169.json
@@ -1 +1 @@
-{"null": 1.7525758659413262}
\ No newline at end of file
+{"LANTUS": 10.779527465946336, "null": 1.4801251538262696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/317.json
index 59ed0de5da8..2e9c73cb7ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/317.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/317.json
@@ -1 +1 @@
-{"OMALIZUMAB": 120.3782051321448}
\ No newline at end of file
+{"COMIRNATY": 4.7793669675371575, "HIZENTRA": 19.759136146347267, "ROACTEMRA": 9.763824171678475, "SPIKEVAX": 1.0609727760044203, "VAXZEVRIA": 1.0982579470574996, "null": 0.4199312930521224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3170.json
index 90d9b6e079d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3170.json
@@ -1 +1 @@
-{"ATRIPLA": 27.27290901990138, "FORSTEO": 8.959882516500628, "LANTUS": 1.302425478733967, "STRIBILD": 11.484953535141832, "SUBOXONE": 5.898135360144878, "TRUVADA": 15.340182869365684, "XELJANZ": 2.261601321933054}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3171.json
index 15574012c4f..06d47cc9625 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3171.json
@@ -1 +1 @@
-{"null": 4.406448101978552}
\ No newline at end of file
+{"AVANDIA": 22.041970804782157, "AZATHIOPRINE": 11.627356177765458, "JANUMET": 6.777410996784672, "null": 5.47358410413594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3172.json
index 5937358d594..246d4859d03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3172.json
@@ -1 +1 @@
-{"null": 5.756935901160102}
\ No newline at end of file
+{"AVANDAMET": 55.372997306132895, "AVANDIA": 44.21262373050259, "BYETTA": 12.428340299175249, "CLOPIDOGREL": 1.83534020064816, "COMIRNATY": 0.036477682267258, "ELIQUIS": 1.4933179241859278, "HUMALOG": 1.3516234777120966, "JANUMET": 7.868204900619725, "JANUVIA": 7.073050111959407, "JARDIANCE": 2.735303515684218, "LANTUS": 2.8973621421679736, "LEVEMIR": 6.089304046374798, "PLAVIX": 7.940926705767684, "RANOLAZINE": 55.06700379693664, "SPIKEVAX": 0.3145896805839328, "STELARA": 1.6508899995088957, "TRELEGY": 11.867388191222426, "ZOSTAVAX": 3.675734257699109, "null": 1.099725769306207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3173.json
index 7f35b6923dd..12de2d89a0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3173.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.7433305687210905, "ANAKINRA": 8.751303192217922, "ARAVA": 5.173450313585176, "AUBAGIO": 2.5246558499671745, "CIMZIA": 4.2250061033487, "CYMBALTA": 3.0600102475698665, "ENBREL": 4.373285539671607, "FAMPYRA": 10.192195556798971, "HUMALOG": 2.6415203236234994, "IBUPROFEN": 13.470464024160124, "LANTUS": 1.1584569721164488, "METHOTREXATE": 2.601177752903931, "ORENCIA": 59.64259648944277}
\ No newline at end of file
+{"HUMAN": 125.00462914750617, "null": 0.499960377561748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3174.json
index 57843db18a7..dd97d4129fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3174.json
@@ -1 +1 @@
-{"ABATACEPT": 4.600584458865994, "ADALIMUMAB": 24.87681844314307, "ANAKINRA": 5.857649107687596, "APREMILAST": 24.512138915914203, "ARAVA": 11.55157223123226, "COSENTYX": 2.8642970779499137, "ENBREL": 14.096454907523595, "HUMIRA": 3.78846375066755, "METHOTREXATE": 2.205163117056464, "RITUXIMAB": 8.287996516877763, "SIMPONI": 2.0552890286926617, "XELJANZ": 10.230879616240076}
\ No newline at end of file
+{"ACLIDINIUM": 51.48872669795927, "APIDRA": 2.066943641702332, "ARAVA": 0.1734432771538844, "AVANDAMET": 116.1391656005156, "AVANDIA": 118.96077847315031, "BYETTA": 5.515673891298287, "CLOPIDOGREL": 3.492660467900877, "CYMBALTA": 0.824059731457382, "HUMALOG": 2.546450620576539, "JANUMET": 4.45664328993432, "JANUVIA": 6.714038317963123, "JARDIANCE": 7.471900758679796, "LANTUS": 7.961728683725709, "LEVEMIR": 2.604397774343771, "PANTOPRAZOLE": 7.93023263083567, "PLAVIX": 1.3515789528610282, "ROSIGLITAZONE": 47.88629246673455, "SPIKEVAX": 0.0422585356682342, "STELARA": 1.2901543221423484, "ZOSTAVAX": 1.6822045397959218, "null": 1.1180207070158323}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3175.json
index 7799e7dccec..1eb0db42793 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3175.json
@@ -1 +1 @@
-{"AVASTIN": 14.77510698005488, "BEVACIZUMAB": 4.166772384721566, "CELLCEPT": 2.123860260213246, "CIMZIA": 13.356956916665265, "COSENTYX": 2.4095890673210354, "ENTYVIO": 21.336964819544228, "HUMALOG": 1.0892482021102332, "HUMIRA": 16.805968862712607, "KEYTRUDA": 4.291905273152781, "LENVIMA": 31.70052200738032, "MEKINIST": 3.3935040049406746, "NEXAVAR": 3.379818527178277, "REMICADE": 13.194692378923865, "SIMPONI": 3.3460958039257145, "STELARA": 31.488543362110903, "SUTENT": 3.5031858035228205, "VOTRIENT": 3.5527752285482546, "XELJANZ": 2.5376580673705207}
\ No newline at end of file
+{"null": 0.6017316018275947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3176.json
index 5ab8c67f020..ab80f0659b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3176.json
@@ -1 +1 @@
-{"HUMIRA": 63.574617661321135, "STELARA": 30.4405988832484}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3177.json
index 27b114f2018..bc0268f2db5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3177.json
@@ -1 +1 @@
-{"SUTENT": 9.323755396881577}
\ No newline at end of file
+{"ANGIOX": 1089.2542757072365, "CLOPIDOGREL": 10.735544831720093, "COMIRNATY": 0.3980423356119973, "SPIKEVAX": 0.770868584516918, "VAXZEVRIA": 0.4132879477408328, "null": 0.8835435404588866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3178.json
index a843f579c9c..2b84cc1f5b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3178.json
@@ -1 +1 @@
-{"AIMOVIG": 3.780103456668012, "IBUPROFEN": 3.09152143804726, "KEPPRA": 1.949071222871341, "LEVOFLOXACIN": 14.22100656015794, "PANTOPRAZOLE": 6.132837367667432, "null": 5.581241084105412}
\ No newline at end of file
+{"null": 1.3001979912474408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3179.json
index dad3fc4317b..98ed017000e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3179.json
@@ -1 +1 @@
-{"ABILIFY": 5.12408247548939, "AFINITOR": 1.5823533703103887, "BYETTA": 2.623543066663012, "CRIXIVAN": 36.12835741627367, "CYTARABINE": 1.157910030130079, "ENOXAPARIN": 7.2241283802444896, "EXJADE": 2.78815378709898, "FLEBOGAMMA": 6.981764310056512, "FORSTEO": 1.4033359042954778, "FORXIGA": 4.178131263543519, "GARDASIL": 1.7357779328862912, "HIZENTRA": 1.8247992818963448, "INSULIN": 13.799449972360543, "JANUMET": 1.4768169273972604, "JARDIANCE": 1.5409805382256716, "MEPOLIZUMAB": 2.9250859050954965, "NUCALA": 2.0012056515420373, "OPSUMIT": 1.4268158045666193, "PRIVIGEN": 3.1278612369409178, "SAXENDA": 1.584035190522198, "SHINGRIX": 1.3793933563290832, "SOLIRIS": 1.201738888024311, "SUTENT": 1.8191141595865687, "VOTRIENT": 1.630281278993047, "XELJANZ": 1.2003458308993398, "XTANDI": 1.0522675657383844, "ZOSTAVAX": 1.464743306885134}
\ No newline at end of file
+{"null": 1.1486119919824682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/318.json
index 4d17ebfdf82..9f2ab925378 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/318.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/318.json
@@ -1 +1 @@
-{"null": 1.4303389403425195}
\ No newline at end of file
+{"COMIRNATY": 1.7524390210907643, "MODERNA": 23.25520607601861, "SPIKEVAX": 1.5062009261877558, "VAXZEVRIA": 0.3961911850882563, "null": 0.9334239744795276}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3180.json
index c82dd5e0279..f78b248cd84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3180.json
@@ -1 +1 @@
-{"null": 4.802594096429057}
\ No newline at end of file
+{"ANGIOX": 37.35231260250416, "APIDRA": 1.5109917895935472, "ATRIPLA": 0.0879361359076205, "AVANDAMET": 16.115326487772382, "AVANDIA": 16.685233151392737, "BENLYSTA": 1.421154286092055, "BRILIQUE": 4.724997638308323, "BYDUREON": 5.671068928034438, "BYETTA": 2.820992169543418, "CLOPIDOGREL": 5.416234998908356, "COMIRNATY": 0.0902972431121409, "CYMBALTA": 0.5397694618715481, "ELIQUIS": 1.3116497145502173, "FORSTEO": 0.5521876310038581, "FORXIGA": 4.128635020652854, "HUMALOG": 3.982642055862291, "HUMIRA": 2.1431196886137145, "ICLUSIG": 4.181051839897023, "INSULIN": 2.372296589033998, "INTEGRILIN": 13.338233526765263, "JANUMET": 0.7955776936261967, "JANUVIA": 0.7151791204731166, "JARDIANCE": 1.9080309408600349, "LANTUS": 3.247733509403814, "LEVEMIR": 3.3322823226738114, "MICARDIS": 1.9623566257135612, "NEXAVAR": 0.572836753046272, "NORVIR": 4.184810950196142, "PEGASYS": 0.5046858390007446, "PEGINTRON": 0.7060326589617317, "PLAVIX": 23.347870957719294, "RITUXIMAB": 1.977510435171551, "SIMPONI": 0.4764250165255575, "SPIKEVAX": 0.2291094252850698, "STELARA": 0.855925121562377, "TASIGNA": 10.819215272565833, "TESTOSTERONE": 6.848311564568541, "TICAGRELOR": 6.677786758875344, "TOZINAMERAN": 0.1223073966875682, "TRELEGY": 1.2750354720656196, "TRULICITY": 1.3102522693273246, "VAXZEVRIA": 0.0353875353579209, "VIAGRA": 3.917861189597612, "VICTOZA": 2.3531857502563147, "XELJANZ": 1.0428334106891652, "null": 1.804479086772728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3181.json
index 1df78a47d9c..75d9e957e09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3181.json
@@ -1 +1 @@
-{"CHAMPIX": 12.205967416860345, "null": 2.519817039689048}
\ No newline at end of file
+{"ANGIOX": 7196.372120109358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3182.json
index bbd16a7302e..a8a542419ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3182.json
@@ -1 +1 @@
-{"ABILIFY": 5.291493372011236, "CHAMPIX": 14.006863644612585, "CYMBALTA": 3.224675324180957, "LATUDA": 17.755906768969258, "OLANZAPINE": 4.068530612828039, "ZYPREXA": 8.35110303422757, "null": 1.822814626150029}
\ No newline at end of file
+{"null": 1.1487346130258136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3183.json
index 37b8987e79a..53a4e432348 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3183.json
@@ -1 +1 @@
-{"null": 5.896765777660648}
\ No newline at end of file
+{"BRILIQUE": 43.60934881001079, "CLOPIDOGREL": 11.338779171427596, "EFIENT": 215.6312444510972, "PLAVIX": 33.19343088637776, "null": 1.237834176894082}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3184.json
index fd218180a48..343c5b25a21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3184.json
@@ -1 +1 @@
-{"1": 77.6903463799255, "ABASAGLAR": 2.3712220495380154, "AFINITOR": 2.0057526816575786, "AIMOVIG": 2.209211075706495, "BETMIGA": 2.274305979639096, "BIKTARVY": 1.9627463150652973, "BONVIVA": 2.4571567610133944, "BOSULIF": 2.5507338799764017, "BRINTELLIX": 2.3325202089952977, "BYDUREON": 1.9964581411701248, "BYETTA": 1.9968188914284373, "CABOMETYX": 1.9705753816601927, "CHAMPIX": 4.416416622252958, "CIRCADIN": 4.70707468977219, "CLOPIDOGREL": 1.2654497271810317, "COAPROVEL": 1.03086433115161, "COMBIVIR": 1.66829233689054, "DUAKLIR": 32.58373464757106, "DULOXETINE": 1.5516505347667338, "ELLAONE": 3.811313689249257, "ENTRESTO": 1.015143128005441, "ENTYVIO": 4.684183963464483, "ESBRIET": 3.69649103657628, "ESMYA": 3.319764778317203, "ESOMEPRAZOLE": 2.144860094268031, "EUCREAS": 4.133856811584389, "EVISTA": 1.3120172790840818, "EXJADE": 1.374941054469015, "FORSTEO": 1.7875790285396145, "FORXIGA": 2.0038485941245545, "GALAFOLD": 3.172138014361128, "GALVUS": 1.679946109893332, "GENVOYA": 3.347664316183144, "HUMIRA": 1.3006172183904072, "IBRANCE": 1.3505269641465596, "INFANRIX": 2.260057314961529, "INLYTA": 1.5086507530767193, "ISENTRESS": 1.0246689198012493, "JAKAVI": 1.458866764317847, "JANUMET": 2.4907596193313366, "JANUVIA": 2.048451849466444, "JARDIANCE": 2.1335215158047047, "KAFTRIO": 2.6677677561854525, "LIXIANA": 1.8018641737833965, "LYNPARZA": 1.095598135111889, "MELATONIN": 1.853480573341142, "MICARDIS": 1.8790699357408915, "NINLARO": 1.4572213442372246, "OFEV": 5.593547113798278, "OPSUMIT": 1.3141760685310533, "ORKAMBI": 1.7211512752619562, "OXYBUTYNIN": 6.802921438206613, "OZEMPIC": 5.956824684604923, "PANTOPRAZOLE": 1.214779964235298, "PREVENAR": 2.615509628668609, "RANEXA": 3.698313903196732, "REMSIMA": 18.670338473500045, "ROTATEQ": 6.612665176735744, "RUBRACA": 1.16715507989042, "RYBELSUS": 12.224186674369385, "SAXENDA": 9.189088739427334, "SILDENAFIL": 1.0873797114451051, "SPRYCEL": 1.110391481160358, "SUTENT": 4.166439158126159, "TEDUGLUTIDE": 24.45448797963413, "TOUJEO": 1.0900618323473836, "TOVIAZ": 1.8112668873052284, "TRIUMEQ": 3.036245466205297, "TRULICITY": 12.784514356380676, "VELTASSA": 7.530204623928852, "VICTOZA": 5.205338735664096, "VIMPAT": 1.2609757207662098, "VOTRIENT": 1.6580638026339192, "XELJANZ": 2.3792070588223178, "XTANDI": 1.593712316336731, "ZEJULA": 5.670689525681608, "null": 1.6920586470020205}
\ No newline at end of file
+{"AVANDAMET": 8.483288827221196, "AVANDIA": 5.277059551346465, "BRILIQUE": 15.41826149953554, "BYETTA": 2.541753336513328, "CHAMPIX": 1.3337508861738645, "CICLOSPORIN": 1.5583211332001972, "CLOPIDOGREL": 8.2167662742672, "COMIRNATY": 0.3147712054081088, "DULOXETINE": 8.298544270379482, "EFIENT": 38.20466029815059, "ELIQUIS": 0.9753221716181028, "FORSTEO": 1.4502097891040662, "FORXIGA": 4.113628952555229, "ICLUSIG": 28.538648969253117, "INSULIN": 2.614520162414578, "JARDIANCE": 1.208573804419092, "NEXAVAR": 2.170399361140439, "NILOTINIB": 41.54664126575262, "OLANZAPINE": 1.2494686547537484, "PLAVIX": 6.492658880177509, "SPIKEVAX": 0.2728663200955764, "STELARA": 0.9960231403059088, "TASIGNA": 15.071508438671913, "TICAGRELOR": 15.183550255424525, "VIAGRA": 2.757629495168243, "null": 1.1238170628016912}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3185.json
index 23a7ad7cc12..b84343e9df4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3185.json
@@ -1 +1 @@
-{"SIMPONI": 203.7543551350103}
\ No newline at end of file
+{"ANGIOX": 731.2447008081293, "AVANDIA": 4.819469542878076, "BRILIQUE": 10.919948193184444, "CHAMPIX": 1.6685647855708452, "CLOPIDOGREL": 17.218598682537348, "COMIRNATY": 0.514850890508404, "ELIQUIS": 0.8463639987121037, "INTEGRILIN": 179.42443305229153, "PLAVIX": 13.128898685482104, "SPIKEVAX": 0.330446816546379, "TOZINAMERAN": 0.5882731104611056, "VAXZEVRIA": 0.8117238355663127, "ZYLLT": 160.65552500694767, "null": 0.834118728107272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3186.json
index 68dda31f627..5c9e589bdc8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3186.json
@@ -1 +1 @@
-{"KEPPRA": 9.800274787158592, "OLANZAPINE": 30.211421559429255, "null": 2.4710532678765573}
\ No newline at end of file
+{"NOVOSEVEN": 1849.405728704364, "null": 0.584003753717194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3187.json
index 2d10f642fcf..4db056d14a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3187.json
@@ -1 +1 @@
-{"null": 2.284346863724446}
\ No newline at end of file
+{"null": 0.502161135947256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3188.json
index 879ef91b034..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3188.json
@@ -1 +1 @@
-{"null": 9.18078064038258}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3189.json
index 2cdb7062857..439c968904e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3189.json
@@ -1 +1 @@
-{"JANUMET": 851.6940466569175}
\ No newline at end of file
+{"DOCETAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/319.json
index 59ed0de5da8..00765d39494 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/319.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/319.json
@@ -1 +1 @@
-{"OMALIZUMAB": 120.3782051321448}
\ No newline at end of file
+{"null": 1.039154314739532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3190.json
index fe7d5a63235..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3190.json
@@ -1 +1 @@
-{"null": 1.394156504884386}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3191.json
index c610f1bf5b9..4c0caa7fb5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3191.json
@@ -1 +1 @@
-{"ENTRESTO": 5.647244532364818, "FORSTEO": 2.2533251950915405, "FORXIGA": 8.884714581426127, "IRBESARTAN": 10.47750429717237, "JARDIANCE": 5.020399545658953, "OLANZAPINE": 2.7311109480522857, "PEGASYS": 1.7138916085738016, "PEGINTRON": 2.172692381010178, "ROTATEQ": 21.33518026677384, "SUTENT": 5.140574056325409, "SYNAGIS": 8.338446272164388, "TRULICITY": 4.781537736322375}
\ No newline at end of file
+{"AIMOVIG": 3.705681323963725, "ALEMTUZUMAB": 5.9961551031085545, "ASPARAGINASE": 19.581115861660333, "AUBAGIO": 2.1496519565550347, "AZATHIOPRINE": 3.6535251170713474, "BENLYSTA": 8.80104592298463, "CICLOSPORIN": 1.321492277162139, "CIMZIA": 1.4458488486091006, "COMIRNATY": 0.4456061451698436, "COSENTYX": 6.079562122734647, "DESCOVY": 18.06784843576593, "DEXAMETHASONE": 1.5928112642268544, "ELIQUIS": 0.4907309423638429, "ENTRESTO": 1.1613705258681148, "ENTYVIO": 2.3506711652849472, "ENVARSUS": 170.60553019527586, "ESBRIET": 4.507894849881883, "FAMPYRA": 23.25502477499112, "HUMALOG": 0.5916933514850188, "IBRANCE": 0.785090681970598, "JAKAVI": 7.735810487359698, "JARDIANCE": 0.7741035071585168, "KALETRA": 3.78217666679326, "KESIMPTA": 38.14334658421333, "KEYTRUDA": 3.495616055618497, "MEPOLIZUMAB": 5.152137626814872, "NUCALA": 7.868603527246007, "OFEV": 3.8549080581601096, "OPDIVO": 3.072776966096285, "PLEGRIDY": 13.05535054587532, "RINVOQ": 10.590958273888855, "ROACTEMRA": 1.9621275228380293, "SHINGRIX": 3.583032788599771, "SIMPONI": 5.7565194817689, "SPIKEVAX": 0.3679612148903923, "STELARA": 0.7227017519412204, "SYMTUZA": 52.27277024392599, "SYNAGIS": 9.377845584677708, "TRELEGY": 11.161086795952944, "VAXZEVRIA": 0.0989779816689989, "VELTASSA": 9.024962822027758, "XELJANZ": 1.470721727364188, "XOLAIR": 2.790707510922037, "null": 0.5484044087838118}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3192.json
index 565444e1db9..71e0a224a3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3192.json
@@ -1 +1 @@
-{"null": 1.2574723005795418}
\ No newline at end of file
+{"null": 0.3315020710754227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3193.json
index 5058af2fc1f..1cda26f6035 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3193.json
@@ -1 +1 @@
-{"PEGINTRON": 15.2184793924201, "null": 2.4793349669065576}
\ No newline at end of file
+{"VAXZEVRIA": 11.70377963696806}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3194.json
index 1f5fa6c7c7e..7e8a68796c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3194.json
@@ -1 +1 @@
-{"ABACAVIR": 33.842645036699935, "ACTOS": 9.47395991303104, "ADCIRCA": 10.58654439901657, "ADEMPAS": 17.165358852597656, "AMBRISENTAN": 15.685837016848804, "APIDRA": 1.1191017342678855, "ARANESP": 1.4084273027645553, "AVANDAMET": 4.868525016089837, "AVANDIA": 7.802737628966721, "BENLYSTA": 1.0043307937207784, "BOSENTAN": 7.329738405030459, "BOSULIF": 6.942649593110662, "BOSUTINIB": 10.9499363878384, "BUMETANIDE": 5.860197558167768, "BUPIVACAINE": 1.0279517359853565, "BYETTA": 1.5478790982009285, "CELECOXIB": 5.198098434574378, "CLOPIDOGREL": 4.099905228238516, "DASATINIB": 2.48633285865932, "ELIQUIS": 1.9143092509826476, "ENBREL": 1.3269126046759978, "ENTRESTO": 4.289573985110072, "ESBRIET": 1.616020693759778, "EVRA": 2.3239544910469445, "EXFORGE": 3.9041960698045415, "EXJADE": 1.2933425154151463, "FASLODEX": 1.2964876665265677, "FORSTEO": 1.8321523277776977, "GLIVEC": 4.104582543104602, "HUMALOG": 1.989359341517993, "HUMIRA": 1.5439479457033296, "IBRANCE": 1.16789167834306, "ICLUSIG": 1.4930713204823045, "ILARIS": 33.55202256210019, "IMATINIB": 4.42129688860326, "INSULIN": 1.137704057698926, "IVABRADINE": 32.60789961809711, "JANUVIA": 1.035496836503386, "KYPROLIS": 1.2874461419749574, "LANTUS": 1.6018686690107486, "LYRICA": 2.0908405856265952, "MACITENTAN": 14.26391008373622, "MULTAQ": 2.590595479182258, "NILOTINIB": 2.1735223635987717, "NINLARO": 1.8918567842498435, "OCALIVA": 2.225937888796746, "OFEV": 1.0759964973200422, "OPSUMIT": 27.254934958004824, "ORENCIA": 21.144083904748868, "OZEMPIC": 3.3487453387948785, "PEMETREXED": 2.3767697755699704, "RAPAMUNE": 2.5186913686275254, "RASILEZ": 2.982521017744182, "REVATIO": 20.92128598202749, "REVLIMID": 2.093020117838732, "RINVOQ": 1.1798884505223644, "ROSIGLITAZONE": 9.649490985024938, "RUBRACA": 1.196133645500858, "SEMAGLUTIDE": 10.271647889462724, "SILDENAFIL": 5.228181747611984, "SOLIRIS": 1.0200477759751116, "SOMATROPIN": 3.469666284043281, "SPIRONOLACTONE": 2.71226278834474, "SPRYCEL": 13.009506275855774, "SUTENT": 1.8957328454552351, "TASIGNA": 2.621310339943341, "TOUJEO": 1.117124368938082, "TOVIAZ": 2.902403617672097, "TRACLEER": 13.74204449800592, "TRELEGY": 1.4002735968066395, "TRISENOX": 7.3652338003123585, "UPTRAVI": 14.685715697980688, "VALSARTAN": 1.464097638734409, "VELTASSA": 4.536391466188369, "VOTRIENT": 1.1903535823406215, "XALKORI": 2.656702451330084, "XELJANZ": 1.0847601907333817, "XTANDI": 1.8810489267107504, "XYREM": 1.4672225879081129, "ZOSTAVAX": 1.7473524861828669, "null": 1.0514036705556242}
\ No newline at end of file
+{"BENLYSTA": 25.31449839667781, "COMIRNATY": 0.2614768415950233, "COSENTYX": 8.116381873613468, "LEVOFLOXACIN": 7.50158635129619, "MEPOLIZUMAB": 12.121675424153365, "NUCALA": 34.8889934152344, "SPIKEVAX": 0.4329353480762031, "TRELEGY": 30.448675424809327, "null": 0.3704885177632224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3195.json
index 95973d3a731..6c446cce79c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3195.json
@@ -1 +1 @@
-{"VORICONAZOLE": 921.6795302682484}
\ No newline at end of file
+{"null": 35.89849273353744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3196.json
index 221e2fe6f40..50ddfda542c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3196.json
@@ -1 +1 @@
-{"VFEND": 93.42640505607532, "VORICONAZOLE": 1698.8237236018088}
\ No newline at end of file
+{"LANTUS": 12.103119653304766, "null": 1.1224606645002349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3197.json
index 33253ebe090..b28cc5c4981 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3197.json
@@ -1 +1 @@
-{"ADCIRCA": 5.008542459656376, "ADEMPAS": 6.115299737631473, "AFINITOR": 1.4944392447291803, "AIMOVIG": 2.240911460250971, "ALEMTUZUMAB": 2.7850268086262484, "AMBRISENTAN": 6.205495925250792, "APROVEL": 1.9216482410520548, "ARZERRA": 4.12308805517138, "AVASTIN": 1.0354908607516118, "BEXSERO": 1.2804949873774618, "BEXTRA": 4.442430610325446, "BOSENTAN": 2.3685452636759696, "BRIDION": 3.530232649860551, "CABAZITAXEL": 2.6711695197296224, "CAELYX": 12.435846694801675, "COMTAN": 1.193277238074108, "DARZALEX": 1.3291935468166365, "DEXAMETHASONE": 1.828498260561316, "DOCETAXEL": 1.15261683254778, "EMEND": 4.939116509783689, "ERBITUX": 1.0745424063462556, "ERENUMAB": 1.9352075170218797, "EXFORGE": 1.7236144551737322, "FAMPYRA": 1.739679782173619, "FASENRA": 1.7934683045322075, "FASLODEX": 1.2879521693032123, "FENTANYL": 1.853495999469932, "FLEBOGAMMA": 10.991342307963158, "FORSTEO": 1.4416338337149073, "GARDASIL": 1.0567138461637426, "GAZYVARO": 3.347854905861323, "GREPID": 11.412226414164977, "HERCEPTIN": 1.4674329954307532, "HIZENTRA": 1.7087184770900892, "HYDROCORTISONE": 2.610534132611916, "IBUPROFEN": 2.116595295439533, "INFANRIX": 1.3642215985627029, "INFLIXIMAB": 2.207674021690632, "JEVTANA": 1.871707493818439, "KIOVIG": 5.503629325473761, "LEMTRADA": 2.732428192494343, "LEVOFLOXACIN": 1.217353035954187, "LUTATHERA": 8.427859626246216, "MACITENTAN": 4.199914013289733, "MENVEO": 4.363958105086375, "MEPOLIZUMAB": 1.0140208410615756, "MIDAZOLAM": 1.0795217203670395, "MIRCERA": 12.91511937072492, "MIRVASO": 31.52152054501875, "MMRVAXPRO": 1.025565291887372, "NAGLAZYME": 1.1332461867198098, "NEULASTA": 1.7536801891524434, "NIMENRIX": 1.619664464657548, "OCRELIZUMAB": 8.826861607626638, "OMALIZUMAB": 1.0290079876015414, "ONCASPAR": 4.244007194839566, "OPSUMIT": 3.906152391992839, "OXYBUTYNIN": 2.6806950944321217, "PACLITAXEL": 2.9985932135868434, "PERJETA": 6.53996650230572, "PERTUZUMAB": 4.300065078677275, "PLEGRIDY": 1.0459416178060037, "PRIVIGEN": 5.949458327414318, "REMICADE": 3.5933305221984795, "REVATIO": 2.2021747149946465, "RIXATHON": 5.677521770463573, "ROACTEMRA": 1.0129726788153837, "SILDENAFIL": 5.172087673620214, "SUFENTANIL": 1.0503074952228328, "TAXOTERE": 3.3897819379479044, "TECFIDERA": 13.435949972517502, "TORISEL": 5.590008523980762, "TOZINAMERAN": 1.0936339547123108, "TRACLEER": 2.161731312289462, "UPTRAVI": 6.437835378927376, "VIAGRA": 4.921538864250029, "XOLAIR": 3.7167230737031383, "null": 2.3398926738851915}
\ No newline at end of file
+{"null": 1.0697945780850726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3198.json
index 671395e8265..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3198.json
@@ -1 +1 @@
-{"CHAMPIX": 1.6791131597335949, "FENTANYL": 2.240787056722896, "GARDASIL": 1.9245718364242463, "OLANZAPINE": 2.260484008020889, "PREGABALIN": 23.09488376151867, "SUBOXONE": 3.3301114786820745, "null": 3.2259250312244188}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3199.json
index babd7a6888a..71b793d5a90 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3199.json
@@ -1 +1 @@
-{"BENZODIAZEPINES": 129.36827053141727, "BRIVIACT": 42.01311000489026, "BUSULFAN": 7.644417728075359, "FYCOMPA": 64.32892925188159, "GARDASIL": 2.3153184668312807, "KEPPRA": 58.98607733155528, "LACOSAMIDE": 107.43070588901185, "LEVETIRACETAM": 50.58469381913426, "VIMPAT": 32.42546357454082, "null": 1.1526176936648227}
\ No newline at end of file
+{"INLYTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/32.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/32.json
index 6a44c19a16e..da91bc1d130 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/32.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/32.json
@@ -1 +1 @@
-{"AIMOVIG": 1.3505418951209176, "AUBAGIO": 1.072867498139406, "COMIRNATY": 1.522521798577192, "ENTYVIO": 5.567865820834672, "EXJADE": 1.1763393345247803, "FORXIGA": 1.255537151121935, "INFANRIX": 4.7365412803820215, "MMRVAXPRO": 2.2191072859617997, "OFEV": 1.6414364496536955, "ROTATEQ": 19.91638527895577, "SAXENDA": 1.5005478510832848, "SPIKEVAX": 1.1086249683848377, "SUTENT": 1.3647858953708178, "TAMIFLU": 3.903878360679762, "VAXZEVRIA": 2.902137949982365, "VOTRIENT": 1.0725417564789252, "XELJANZ": 2.3928075408709506, "null": 1.0327575333542438}
\ No newline at end of file
+{"ABACAVIR": 13.045411982848195, "AFINITOR": 9.758587289560127, "CICLOSPORIN": 8.680605595868215, "COMIRNATY": 0.3135801624972146, "JANUMET": 10.351679757536989, "NEXAVAR": 14.390225556137, "null": 0.3353217273075909}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/320.json
index 7b9e77d8656..ffed2e44063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/320.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/320.json
@@ -1 +1 @@
-{"CICLOSPORIN": 14.534236189100652, "CYTARABINE": 47.05986632481543}
\ No newline at end of file
+{"null": 0.8953782293383834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3200.json
index 1e150e11b33..f0a40814ee6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3200.json
@@ -1 +1 @@
-{"ADCIRCA": 119.50748750356352, "SOMATROPIN": 148.3289695208738, "THIOTEPA": 679.6024211412794, "null": 1.0337320013888864}
\ No newline at end of file
+{"KEYTRUDA": 22.799451017272897, "null": 0.9995709322665152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3201.json
index 3ae6a609073..abdf2cebe92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3201.json
@@ -1 +1 @@
-{"CELLCEPT": 17.13933981185598, "CICLOSPORIN": 39.97405163896738, "SOMATROPIN": 77.75742512517103, "TRUVADA": 1.9029750298411148}
\ No newline at end of file
+{"ATAZANAVIR": 36.97748983346886, "BUDESONIDE": 11.55515201522584, "COMIRNATY": 0.0757215572879365, "FLUTICASONE": 44.44388182022068, "HYDROCORTISONE": 19.207637872764312, "IPILIMUMAB": 7.824902358335052, "KALETRA": 11.619212034519524, "KEYTRUDA": 17.02096377466439, "LOPINAVIR": 64.3585504574103, "NORVIR": 34.022475760079764, "OPDIVO": 17.502826210074264, "PEMBROLIZUMAB": 11.872056966218144, "RELVAR": 15.22020898015522, "RITONAVIR": 88.51905521954818, "null": 1.798417071432418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3202.json
index beb21bfad8d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3202.json
@@ -1 +1 @@
-{"null": 3.1582598847212897}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3203.json
index 175e1e8bbe2..450b4fd133c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3203.json
@@ -1 +1 @@
-{"null": 3.6147353771008457}
\ No newline at end of file
+{"null": 1.4631329108364377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3204.json
index d907830d2fb..55051c68dc8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3204.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 385.2330306315093, "CYTARABINE": 107.95678939511905}
\ No newline at end of file
+{"KEYTRUDA": 8.853636890922294, "null": 1.843741993549856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3205.json
index f8423a1276b..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3205.json
@@ -1 +1 @@
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\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3206.json
index ac8fa3681b8..df2ee908969 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3206.json
@@ -1 +1 @@
-{"null": 2.1596009473666915}
\ No newline at end of file
+{"null": 0.8902025427800571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3207.json
index 139a8a9b8e2..9263fa5f5ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3207.json
@@ -1 +1 @@
-{"null": 3.487298748185552}
\ No newline at end of file
+{"SYNAGIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3208.json
index 3d2fcb1f556..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3208.json
@@ -1 +1 @@
-{"null": 1.2523702638012422}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3209.json
index 6b90a4bba2a..567ca49c614 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3209.json
@@ -1 +1 @@
-{"LANTUS": 14.373825860095536}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/321.json
index e2087313285..b13b14a6f9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/321.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/321.json
@@ -1 +1 @@
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\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3210.json
index 2a62a642c6d..16b4eb97257 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3210.json
@@ -1 +1 @@
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\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3211.json
index ea150de6b6a..2148e63f658 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3211.json
@@ -1 +1 @@
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\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3212.json
index 4844981ff42..0345f8d234d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3212.json
@@ -1 +1 @@
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\ No newline at end of file
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0.3737044654537395, "SILDENAFIL": 0.6742305251441834, "SIMPONI": 0.8530454540252514, "SKYRIZI": 0.9758787579225792, "SOLIRIS": 0.6465115408034411, "SOMATROPIN": 0.3486553095022444, "SORAFENIB": 0.3008855152604484, "SOVALDI": 0.7235122999235474, "SPIKEVAX": 0.956965651613658, "SPINRAZA": 0.4883193473144303, "SPIRONOLACTONE": 0.3683027825788855, "SPRYCEL": 1.1592358949108423, "STELARA": 0.6003023595143112, "STEROIDS": 0.9210076097051756, "STIVARGA": 0.496309060792365, "STRIBILD": 0.0206567052677847, "SUBOXONE": 0.1043251525863267, "SUFENTANIL": 0.2151532926184216, "SUTENT": 0.904208506618609, "SYMTUZA": 1.2541433980449077, "SYNAGIS": 5.18605609126251, "SYNFLORIX": 3.714614937402436, "TACROLIMUS": 0.3441698070020078, "TAFINLAR": 1.008472724501954, "TAGRISSO": 1.470324951221952, "TAMIFLU": 0.8774479382178255, "TASIGNA": 0.6289729367481427, "TAXOTERE": 0.4864445192598692, "TEDUGLUTIDE": 2.177310771427423, "TELMISARTAN": 2.746835024175105, "TEMODAL": 0.2659824050518035, "TEMOZOLOMIDE": 0.1974211824533305, "TERIFLUNOMIDE": 0.8044741085786875, "THALIDOMIDE": 0.1773383381904479, "TICAGRELOR": 0.4551259356769193, "TIVICAY": 0.85421191829446, "TOBI": 12.825271405484347, "TOBRAMYCIN": 1.5196066222314557, "TOCILIZUMAB": 0.469812618040378, "TOLURA": 8.733516326598384, "TORISEL": 1.373195511948449, "TOUJEO": 0.4621464594459096, "TOVIAZ": 0.5869858233928082, "TOZINAMERAN": 1.5148489582362363, "TRACLEER": 1.1447865760140497, "TRACTOCILE": 1.9714205656836097, "TRELEGY": 5.054750546152815, "TREMFYA": 0.4910876389727697, "TRIUMEQ": 1.4193508677553563, "TRODELVY": 0.6392722440797155, "TRULICITY": 0.1198249408417299, "TRUVADA": 0.0295588762610359, "TWINRIX": 0.4211855387183013, "ULTIBRO": 4.571139547105619, "UMECLIDINIUM": 5.213991433501147, "UNSPECIFIED": 0.6727194714529416, "UPADACITINIB": 0.6546980724496707, "VALSARTAN": 0.9151552485356548, "VARENICLINE": 2.592238643858957, "VARICELLA": 4.647407556925456, "VAXZEVRIA": 0.8832713334802597, "VELTASSA": 0.4094867821034501, "VENCLYXTO": 0.3992606229189647, "VENETOCLAX": 0.1839788789836399, "VFEND": 0.427138475881739, "VIAGRA": 0.2465140647809491, "VICTOZA": 0.0795399565177908, "VIMPAT": 0.1438058615109786, "VIRAMUNE": 0.3561133575813721, "VORICONAZOLE": 0.4297169815688925, "VORTIOXETINE": 2.3867835612150863, "VOTRIENT": 0.8694563487861192, "XALKORI": 0.9692565651379992, "XARELTO": 0.4591453498042094, "XELJANZ": 1.6015625671564644, "XELODA": 0.1774994968494657, "XOLAIR": 3.363233825923252, "XTANDI": 0.515633780992103, "XYREM": 0.4243770982507192, "YERVOY": 0.2322546867437433, "ZARZIO": 0.8475570756121014, "ZEJULA": 0.8059790481733117, "ZELBORAF": 0.2343253393484199, "ZEPATIER": 0.6101665719682728, "ZIAGEN": 2.8727930728768216, "ZOMETA": 0.3591410207897202, "ZOSTAVAX": 0.5959848128970444, "ZYPREXA": 0.1766882806338433, "null": 1.134717045097231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3213.json
index 708743ba726..978a8eaa610 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3213.json
@@ -1 +1 @@
-{"ABILIFY": 13.232820404473838, "ASPARAGINASE": 14.7398836433327, "BUPIVACAINE": 10.926526119369782, "BUPRENORPHINE": 6.325865420498625, "CICLOSPORIN": 4.136832615598153, "CIMZIA": 1.2525240689388388, "CLOPIDOGREL": 1.3112696026911486, "COMBIVIR": 31.476179164783108, "DEXAMETHASONE": 5.385572987717242, "FENTANYL": 6.858775124066405, "JARDIANCE": 1.814675068410734, "KALETRA": 6.998429733696829, "KEPPRA": 2.735638230264219, "LEVEMIR": 7.333661966332029, "LEVETIRACETAM": 3.0915571262775283, "NEVIRAPINE": 34.31511743597952, "NOVORAPID": 4.268012105755982, "RECOMBINANT": 977.5496199059312, "SOLIRIS": 3.5202506094449846, "SUBOXONE": 7.343852159233719, "null": 2.021924147383038}
\ No newline at end of file
+{"null": 0.9004185235913372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3214.json
index da2e0b4564d..e206deced44 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3214.json
@@ -1 +1 @@
-{"ATAZANAVIR": 37.39790382436052, "BUPIVACAINE": 120.48872499744046, "FENTANYL": 35.092797117903395, "MIDAZOLAM": 32.37946294066199, "null": 4.746941806689264}
\ No newline at end of file
+{"COMIRNATY": 1.7111947430668155, "null": 0.821531774086839}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3215.json
index 597236302b4..751c9913801 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3215.json
@@ -1 +1 @@
-{"ABILIFY": 3.3994615804209625, "ACTRAPID": 2.909382303100484, "AERIUS": 1.2987991352094814, "ALISKIREN": 2.6157851035844315, "ANTIBIOTIC": 6.945300574762279, "ANTIBIOTICS": 1.865198562235805, "APIDRA": 1.2581344609691398, "APTIVUS": 5.654519907981118, "ARIPIPRAZOLE": 1.6143292577911257, "ATAZANAVIR": 5.007473061321599, "ATOSIBAN": 50.82404342107393, "AZATHIOPRINE": 3.7882817046004913, "BARACLUDE": 1.26327106041193, "BENZODIAZEPINE": 3.3808892362155145, "BENZODIAZEPINES": 3.3457231214169907, "BIKTARVY": 1.500736008726904, "BRIVARACETAM": 2.727986055011248, "BUPIVACAINE": 6.0736251992950665, "BUPRENORPHINE": 15.56832516209769, "BUVIDAL": 6.855405136629372, "CEPHALOSPORIN": 39.82482979404303, "CHLORHEXIDINE": 4.142874731469938, "CICLOSPORIN": 1.6462794871361377, "CINACALCET": 9.842911919899434, "COMBIVIR": 15.014643266201118, "CRIXIVAN": 1.2308409177946689, "DARBEPOETIN": 3.572086143289717, "DARUNAVIR": 9.174438520940107, "DESCOVY": 1.8408118829471605, "DEXAMETHASONE": 3.6758098919873463, "DEXMEDETOMIDINE": 13.070754128487645, "DOLUTEGRAVIR": 6.160317009750506, "DULOXETINE": 1.1783113389530375, "ECULIZUMAB": 7.827990452198647, "EDURANT": 3.931458941239691, "EFAVIRENZ": 7.152886455357908, "EMTRICITABINE": 12.020781934089824, "EMTRIVA": 3.993836754884389, "ENFUVIRTIDE": 7.100088648845284, "ENOXAPARIN": 7.050663440579619, "EPIVIR": 7.530997689333515, "EPOETIN": 4.360072085638552, "ESMYA": 1.117937019437533, "ESOMEPRAZOLE": 1.3223651069896096, "EVIPLERA": 19.495186980924544, "FENTANYL": 6.353202509714267, "FYCOMPA": 1.5588354989842816, "GLYCOPYRRONIUM": 1.4229156500661777, "HUMALOG": 1.6284482410473158, "HUMAN": 4.790408728040396, "HYDROCORTISONE": 2.379052348017592, "ILOPROST": 16.425739907769593, "INFLIXIMAB": 1.2368957252449482, "INSULATARD": 8.687319405670058, "INSULIN": 3.861844136446433, "INTELENCE": 10.041149469213378, "INTERFERON": 1.5982241567855398, "INVIRASE": 1.4501619416373768, "IRON": 12.73538277520314, "ISENTRESS": 19.56125128549391, "KALETRA": 4.508901934644183, "KEPPRA": 2.3197007003555683, "KIOVIG": 2.153870562547876, "KIVEXA": 4.451475981750538, "LACOSAMIDE": 3.9444909902749337, "LAMIVUDINE": 9.90235945375504, "LATUDA": 1.0855772812681852, "LEVEMIR": 8.898565197663387, "LEVETIRACETAM": 5.635095960703141, "LOPINAVIR": 4.427723039245703, "MANNITOL": 3.0986054003782653, "MERCAPTOPURINE": 1.0552035491729417, "MIDAZOLAM": 4.222672279177228, "NALOXONE": 3.5060697833212155, "NEVIRAPINE": 12.142572455099492, "NORVIR": 10.133152246833808, "NOVORAPID": 3.1021002757896534, "OLANZAPINE": 1.1722142552845587, "OPIATES": 29.85030895051288, "OPIOIDS": 14.90641647128799, "OSELTAMIVIR": 14.20124506709699, "OXYBUTYNIN": 1.185481896779025, "PACLITAXEL": 1.6654230756139428, "PANTOPRAZOLE": 1.3212045689340206, "REMICADE": 2.8597898514257443, "REYATAZ": 3.1554473041098103, "SILDENAFIL": 3.8869326701876297, "SOLIRIS": 1.4248461796047558, "STELARA": 1.551041459596926, "SUBOXONE": 24.32588940036343, "SUFENTANIL": 1.1710988738357009, "SUSTIVA": 3.8997189349624337, "TACROLIMUS": 2.2210328204057324, "TENOFOVIR": 3.4396858486596025, "TRACTOCILE": 20.554724924786896, "TRESIBA": 1.6965509621812749, "TRIUMEQ": 1.5180219360847351, "VIGABATRIN": 4.969120428596721, "VIRACEPT": 20.004843570465844, "VIRAMUNE": 2.4677831812204265, "ZONISAMIDE": 2.741425171075988, "ZYPREXA": 1.144055278450557, "null": 3.4075454519191566}
\ No newline at end of file
+{"FENTANYL": 24.712984019231797, "GLIBENCLAMIDE": 134.63686688493428, "JANUMET": 9.335794989734437, "VIAGRA": 20.12346273094249, "null": 1.1385879311757807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3216.json
index 872139d3c56..5b0cca5e15c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3216.json
@@ -1 +1 @@
-{"APIDRA": 31.996543563908563, "ARAVA": 1.5932365172562792, "FENTANYL": 4.532497540841885, "INSULIN": 17.037506530249967, "LANTUS": 11.488353533848493, "OLANZAPINE": 4.034864742812943, "null": 2.540516527616836}
\ No newline at end of file
+{"GARDASIL": 24.228647034438715, "null": 0.3115050818116229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3217.json
index 0da9559f1f6..f4a1802d5ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3217.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3217.json
@@ -1 +1 @@
-{"SUBOXONE": 88.02238582520994, "null": 1.0384158771086405}
\ No newline at end of file
+{"COMIRNATY": 3.7094552762119446}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3218.json
index b871e804876..55486b04324 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3218.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3218.json
@@ -1 +1 @@
-{"ATOSIBAN": 2117.559489195261, "null": 1.0858053225118816}
\ No newline at end of file
+{"COMIRNATY": 0.4504853356165111, "SPIKEVAX": 0.679692755273539, "TELMISARTAN": 95.0725410915532, "TOZINAMERAN": 0.8552583405216075, "VAXZEVRIA": 0.2636711392933592, "ZOSTAVAX": 5.874399362851754, "null": 0.8638719957264305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3219.json
index 0fb9f50c062..2551d96fc2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3219.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3219.json
@@ -1 +1 @@
-{"ABILIFY": 3.2586469485929896, "ADVAGRAF": 29.98462593332849, "ARANESP": 1.8610481551275335, "ARIPIPRAZOLE": 1.8302280504210728, "AZATHIOPRINE": 13.827001883833129, "BUPIVACAINE": 15.9667231857266, "BUPRENORPHINE": 4.1397101691468645, "CAPECITABINE": 2.512012889658638, "CEPHALOSPORIN": 396.3152677772589, "CICLOSPORIN": 5.516318022488767, "CIMZIA": 1.0600687730736773, "CLOPIDOGREL": 1.2730229828556017, "COMBIVIR": 15.135765488134268, "CYTARABINE": 2.3008489458749604, "DEXAMETHASONE": 6.874809424165415, "DOLUTEGRAVIR": 11.893823751249432, "ENOXAPARIN": 16.376616214618622, "EPIVIR": 5.410604103513777, "FENTANYL": 2.7118104232897347, "HUMAN": 4.527883398263985, "HYDROCORTISONE": 3.007923239590444, "INSULIN": 4.790996153703854, "ISENTRESS": 12.554921768447336, "KALETRA": 4.395648781219613, "KEPPRA": 4.650077910988972, "KIVEXA": 30.626395538135064, "LEVEMIR": 2.078601464502144, "LEVETIRACETAM": 2.788827944786607, "METHOTREXATE": 1.2577660713460783, "MIDAZOLAM": 14.83003429392651, "MYCOPHENOLATE": 4.008145349538796, "NORVIR": 11.290556341965608, "NOVORAPID": 4.8300422246110815, "OSELTAMIVIR": 29.65656131696017, "SILDENAFIL": 5.807199561487288, "SOLIRIS": 2.2726505064272544, "SUBOXONE": 6.465238408055325, "TRACTOCILE": 83.26589431194269, "ZYPREXA": 1.462094415783613, "null": 1.972622430673995}
\ No newline at end of file
+{"null": 0.7251000137213048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/322.json
index fdffa6dd24c..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/322.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/322.json
@@ -1 +1 @@
-{"null": 1.7203581838430817}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3220.json
index 689c0e69e1f..c86dded8dbd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3220.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3220.json
@@ -1 +1 @@
-{"ENOXAPARIN": 20.51042388318696, "FENTANYL": 10.61756680091137, "GARDASIL": 4.446274376300782, "SUBOXONE": 7.182697200470504, "null": 2.1146288162081905}
\ No newline at end of file
+{"DULOXETINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3221.json
index 664fdb6b90d..277a07a859e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3221.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3221.json
@@ -1 +1 @@
-{"CICLOSPORIN": 5.995518120404044, "FENTANYL": 54.11360628368904, "GARDASIL": 3.2437543729757685, "null": 1.802868038416532}
\ No newline at end of file
+{"COMIRNATY": 0.4954012721255029, "null": 0.6587010770049713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3222.json
index 5baad788bf9..e0eb7710ca5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3222.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3222.json
@@ -1 +1 @@
-{"ABILIFY": 8.86688467539991, "FENTANYL": 31.12576914329544, "SUBOXONE": 15.168320654258768, "null": 2.932063811107728}
\ No newline at end of file
+{"COMIRNATY": 1.1143132700654634, "null": 0.4586957910737018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3223.json
index b63c4aa5387..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3223.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3223.json
@@ -1 +1 @@
-{"null": 4.979405671064821}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3224.json
index 439e34aae45..f1e724f8d20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3224.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3224.json
@@ -1 +1 @@
-{"null": 2.040534036553507}
\ No newline at end of file
+{"null": 1.6305801185912183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3225.json
index f1bd27a5f69..68779a79ba0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3225.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3225.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 7.534699617903125, "FENTANYL": 4.788915631246089, "SUBOXONE": 18.151206365298155, "TOZINAMERAN": 1.3659627273459676, "null": 1.4816939236810394}
\ No newline at end of file
+{"AIMOVIG": 5.949531211454541, "BRILIQUE": 6.368518903716274, "COMIRNATY": 0.1400779947359136, "ELIQUIS": 2.154440037292226, "ENTRESTO": 4.222639285865616, "GARDASIL": 1.6096696707974305, "HUMALOG": 1.837973109154396, "HYDROCORTISONE": 11.27233427161614, "KEPPRA": 5.530435129765543, "LANTUS": 2.5789187206999284, "LYRICA": 4.434507945980699, "SERTRALINE": 167.3458246406038, "SPIKEVAX": 0.1342841436627424, "SUBOXONE": 3.088171354250926, "VAXZEVRIA": 0.1495016108434181, "ZOSTAVAX": 1.6976904212283406, "ZYPREXA": 2.2033645574720486, "null": 1.6019859511504166}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3226.json
index 3b37a6282ab..8b867afc9f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3226.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3226.json
@@ -1 +1 @@
-{"LEVEMIR": 41.43538494344274, "null": 1.9759185410434932}
\ No newline at end of file
+{"null": 8.821263917706421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3227.json
index 7aa476ff358..9fbbc8f4b40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3227.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3227.json
@@ -1 +1 @@
-{"COMBIVIR": 19.24237843004301, "FLUTICASONE": 111.650517533764, "KEPPRA": 11.826394744251704, "LEVETIRACETAM": 18.912685862336, "null": 1.4703604876450274}
\ No newline at end of file
+{"null": 1.7094405736763596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3228.json
index 3d197ebffc5..eb77187491e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3228.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3228.json
@@ -1 +1 @@
-{"KEPPRA": 22.90792089754053, "null": 1.687910323167438}
\ No newline at end of file
+{"ATRIPLA": 10.843627342245624, "COMIRNATY": 0.1218055294416711, "CYMBALTA": 1.3637830092610224, "ELIQUIS": 2.3918029282704945, "FORSTEO": 2.0073446116279654, "GARDASIL": 1.927302442504138, "HUMALOG": 1.627607328610295, "KEPPRA": 6.768323196800519, "MELATONIN": 28.90594445613771, "OPSUMIT": 1.727241415369671, "SPIKEVAX": 0.109635669003366, "STRIBILD": 5.086296515270692, "SUBOXONE": 7.369881373297337, "TOZINAMERAN": 0.3259097704463797, "TRIUMEQ": 16.00323880016695, "TRUVADA": 5.097710488625307, "VIAGRA": 3.734543129463785, "XELJANZ": 1.4589611525662014, "null": 0.956595349033353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3229.json
index 9c873571f0e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3229.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3229.json
@@ -1 +1 @@
-{"null": 1.6406247505359015}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/323.json
index 7a595600c42..736d01f552e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/323.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/323.json
@@ -1 +1 @@
-{"ABILIFY": 1.8992479386755767, "ACTOS": 6.030206563666552, "ACTRAPID": 1.5519825369524305, "ALOXI": 6.640526091070373, "APIDRA": 2.325831338877234, "ARIPIPRAZOLE": 1.5825524422585064, "ASPARAGINASE": 2.185810600706365, "AVASTIN": 1.5852843414307662, "AZILECT": 2.5745269417249164, "BENZODIAZEPINE": 3.078522396003399, "BONVIVA": 1.1610603207200658, "BUPRENORPHINE": 1.5690735991193974, "CANCIDAS": 2.175993581873835, "CHAMPIX": 1.761351052919007, "CICLOSPORIN": 1.6546538170466178, "COAPROVEL": 2.591545190946273, "CYMBALTA": 1.0633147301998165, "DAPAGLIFLOZIN": 2.625296757176017, "DAPTOMYCIN": 5.509876812962887, "DEFITELIO": 5.130072330182727, "DELAMANID": 1.4974066970623123, "DESCOVY": 3.1681226227730144, "DULOXETINE": 2.6516467344898915, "EBIXA": 2.9400648935380524, "EVENITY": 1.1548102304197618, "FENTANYL": 1.6173885217016637, "FORXIGA": 1.822281889658912, "FYCOMPA": 5.8775045454376045, "GLIBENCLAMIDE": 8.079651360125947, "GLUCAGON": 3.375257157275059, "INSULIN": 2.9138140761592437, "INTRONA": 2.092654666118045, "JANUVIA": 1.755597070023312, "JARDIANCE": 2.877542979619583, "JEVTANA": 2.2973471479308376, "KALETRA": 1.183768200900506, "KEPPRA": 1.0506204125631398, "KEYTRUDA": 1.2757318922067258, "LANTUS": 1.4695507511068453, "LENVIMA": 2.4799665845552, "LEVETIRACETAM": 2.281512622524628, "LEVODOPA": 1.6441949671953469, "LEVOFLOXACIN": 1.2085909201214653, "LOXAPINE": 7.47240532226129, "LYRICA": 3.5281681128856146, "MANNITOL": 5.262091304159024, "MEKINIST": 1.133158291836526, "MEMANTINE": 2.7660166607834733, "METFORMIN": 6.941119395343088, "MICARDIS": 1.6013854513920251, "MIDAZOLAM": 4.247545105585105, "MIRABEGRON": 5.39633365741133, "NALOXONE": 4.9580686514756165, "NEXAVAR": 1.256886314339779, "NOVORAPID": 1.1061107862337602, "OLANZAPINE": 3.4109151356141263, "OPDIVO": 1.5461031180201497, "PALIPERIDONE": 5.854295983308866, "PERAMPANEL": 12.23001555370216, "PRADAXA": 1.6151779508760369, "PREGABALIN": 3.472719776905267, "PROPRANOLOL": 3.2260480695283427, "RASILEZ": 1.263480041970794, "REPAGLINIDE": 5.84545652419119, "RISPERIDONE": 1.548466174506333, "ROTARIX": 8.57877698802745, "SAMSCA": 11.7634952913407, "SIFROL": 1.9401593814837224, "SOVALDI": 2.024050394367631, "STIVARGA": 1.4832405774262365, "TAMIFLU": 9.507906163289748, "TELMISARTAN": 1.9644446446622763, "VECTIBIX": 1.896955946767681, "VELCADE": 4.04357212866022, "VFEND": 5.169284655202852, "VIMPAT": 2.4306724795353998, "VORICONAZOLE": 2.107890333258095, "ZONISAMIDE": 4.500602372188896, "ZYPADHERA": 6.098538538996962, "ZYPREXA": 3.4411979518512434, "null": 2.9394888581026146}
\ No newline at end of file
+{"null": 0.756124293828751}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3230.json
index e9130e7d96e..4579658751c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3230.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3230.json
@@ -1 +1 @@
-{"null": 1.3445297455178007}
\ No newline at end of file
+{"SOMATROPIN": 626.4802843396005, "null": 5.232376849964367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3231.json
index 75376379cd1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3231.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3231.json
@@ -1 +1 @@
-{"COAPROVEL": 126.25983099074926, "null": 3.5304547010535843}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3232.json
index eaedca46cbc..540b93ccdc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3232.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3232.json
@@ -1 +1 @@
-{"null": 3.110179983811206}
\ No newline at end of file
+{"null": 15.739437504705402}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3233.json
index 3c714fa2ed1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3233.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3233.json
@@ -1 +1 @@
-{"null": 14.94675601383527}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3234.json
index 8b78c29e8e6..e10f2267df6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3234.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3234.json
@@ -1 +1 @@
-{"COMBIVIR": 38.79745520228781}
\ No newline at end of file
+{"ELIQUIS": 33.92384438716514, "KEPPRA": 11.252890843714871, "null": 0.5258262764969993}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3235.json
index f58e291a27c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3235.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3235.json
@@ -1 +1 @@
-{"CYTARABINE": 29.339581089205733, "DEXAMETHASONE": 15.589793899208374, "DOXORUBICIN": 60.85012272310657, "GAZYVARO": 82.14643210998236, "LENALIDOMIDE": 145.17564843664542, "METHOTREXATE": 6.749275816961422, "OBINUTUZUMAB": 363.2573263171178, "RITUXIMAB": 39.17102440589634, "STELARA": 7.292687689552457}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3236.json
index 2665889dad5..fd02d511de1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3236.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3236.json
@@ -1 +1 @@
-{"BYETTA": 62.100327209614754, "VICTOZA": 78.31832896643316}
\ No newline at end of file
+{"ELIQUIS": 9.623457680755818, "JARDIANCE": 28.7691326415197, "null": 0.3350412453094251}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3237.json
index 30864342a16..7844d4366f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3237.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3237.json
@@ -1 +1 @@
-{"ABATACEPT": 37.460205707026105, "ACETAMINOPHEN": 56.30894294731588, "ADALIMUMAB": 26.28057589893454, "AMINOSALICYLIC": 1.453552068393, "APREMILAST": 13.266354768790489, "APREPITANT": 67.6329721027273, "ARAVA": 13.90153789143132, "BIKTARVY": 1.9502201413583768, "BOTULINUM": 2.550730441051212, "CERTOLIZUMAB": 15.334742669003152, "CETUXIMAB": 7.631578051542689, "CHLORHEXIDINE": 87.7456234936257, "CIMZIA": 30.64772172568333, "COMBIVIR": 1.3469811250503714, "COSENTYX": 3.7987659768374793, "COTELLIC": 6.105949189442965, "EMTRICITABINE": 2.116534192884324, "INCIVO": 1.0403779472570422, "MYCOPHENOLATE": 2.090261069093498, "RINVOQ": 4.6578291969573975, "RITUXIMAB": 2.685735105547101, "ROACTEMRA": 1.0464416176521336, "TRAMETINIB": 13.794110190105965, "VECTIBIX": 4.164078951846105}
\ No newline at end of file
+{"ALIMTA": 10.038157603883564, "AMBROXOL": 394.00520379334097, "AMLODIPINE": 334.2392335047507, "ATRIPLA": 0.2981546488782688, "BEDAQUILINE": 4.030159294361988, "BIKTARVY": 3.012603968842698, "CAFFEINE": 239.34372577795668, "CICLOSPORIN": 2.335976778162327, "CLOPIDOGREL": 1.7340334865702258, "CUBICIN": 4.480271865471554, "CYMBALTA": 0.950555725738241, "ELIQUIS": 1.948759888475172, "EMTRICITABINE": 10.426168998461415, "ENTECAVIR": 20.202244273293964, "ENTRESTO": 3.23681990328769, "EXJADE": 9.994502285767645, "FORXIGA": 2.0071275594470874, "HEPSERA": 21.44767353389637, "IBUPROFEN": 1.336486924975141, "JAKAVI": 2.8643656107263813, "JARDIANCE": 0.7256417554066535, "KEYTRUDA": 0.4501400437423218, "LEVOFLOXACIN": 119.64661802092944, "LYNPARZA": 2.8380367604013723, "PANTOPRAZOLE": 3.621560435414464, "PEGASYS": 0.391572220148145, "RASILEZ": 12.017358610443214, "TAMIFLU": 2.254653211398667, "TOBRAMYCIN": 25.58619062807742, "TRUVADA": 2.1369872937570418, "VFEND": 1.4242296538710553, "VIREAD": 12.033136367273626, "null": 1.0857541748353046}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3238.json
index b2d7dea07d7..673f26df1a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3238.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3238.json
@@ -1 +1 @@
-{"ROTATEQ": 66.65174812380684, "SYNAGIS": 90.0604154444893, "null": 2.0895536841468973}
\ No newline at end of file
+{"AMLODIPINE": 909.540138114541, "CAFFEINE": 1702.9612475917645, "ENTRESTO": 5.73173930702683, "LEVOFLOXACIN": 99.68814009653433, "null": 0.4810883632121134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3239.json
index 47a17cd2322..3f71d0e6cc6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3239.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3239.json
@@ -1 +1 @@
-{"null": 1.3959986505165196}
\ No newline at end of file
+{"null": 0.970950789365552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/324.json
index 9ac4e1b6d50..01d46c4e047 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/324.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/324.json
@@ -1 +1 @@
-{"null": 1.5858714257349935}
\ No newline at end of file
+{"COMIRNATY": 6.401559349889624, "ELLAONE": 43.08668577799354, "MODERNA": 10.18539310419225, "OVITRELLE": 51.017414811595714, "SPIKEVAX": 2.3977203733597774, "TOZINAMERAN": 2.069224810239992, "VAXZEVRIA": 0.6388852306681115, "null": 0.2663288083283204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3240.json
index dd7784aac49..0251017b5d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3240.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3240.json
@@ -1 +1 @@
-{"ABACAVIR": 240.7774194936877, "APIXABAN": 1.2959235291902511, "CLOPIDOGREL": 1.8359822793146408, "DULOXETINE": 4.949228749046713, "ENBREL": 6.081150035495683, "GARDASIL": 4.997603417966292, "HUMIRA": 4.736377243973619, "INFANRIX": 6.37120734022315, "METFORMIN": 21.643411920315177, "METHOTREXATE": 3.545669948095321, "MMRVAXPRO": 1.099875345181769, "OMALIZUMAB": 11.280232486026078, "ORENCIA": 59.89588168216377, "ROTATEQ": 3.811296640628752, "XOLAIR": 4.486514102666203}
\ No newline at end of file
+{"ACLIDINIUM": 15.79355590154366, "ADALIMUMAB": 2.537896496830896, "AFINITOR": 9.870824565774306, "AMBRISENTAN": 76.48666038426065, "ARAVA": 2.949820818335621, "BUPIVACAINE": 41.76875957400133, "CICLOSPORIN": 1.8695141810064844, "COMIRNATY": 0.0826018814294167, "COSENTYX": 2.0546188707765927, "CUBICIN": 12.116951230433182, "GLYCOPYRRONIUM": 44.63352807829998, "HYDROCORTISONE": 6.031389503242374, "LEFLUNOMIDE": 17.44135697799511, "LYRICA": 4.739472695522146, "MEPOLIZUMAB": 15.718223876537126, "NUCALA": 5.741751923730332, "OMALIZUMAB": 3.466951939812779, "SPIKEVAX": 0.1095952054131623, "VAXZEVRIA": 0.0832692111534883, "XELJANZ": 1.037242286822194, "null": 1.0076459357861278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3241.json
index 238e676077a..cf5bda9e3e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3241.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3241.json
@@ -1 +1 @@
-{"CHAMPIX": 3.040702214607864, "COSENTYX": 4.437244035441716, "COVID19": 2.65731507528003, "INCIVO": 9.583655957208135, "JARDIANCE": 1.9931980188764948, "KEPPRA": 2.1329299066659426, "SAXENDA": 9.9954406755654}
\ No newline at end of file
+{"COMIRNATY": 2.2559285948500323, "SPIKEVAX": 0.4903667790843055, "VAXZEVRIA": 0.4333196454639005, "null": 0.5838657079001591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3242.json
index c59c84ce6d4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3242.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3242.json
@@ -1 +1 @@
-{"ABILIFY": 4.168067091307857, "ARIPIPRAZOLE": 12.503472841667328, "BRINTELLIX": 7.71790633905546, "CHAMPIX": 1.9396010395526244, "CYMBALTA": 2.7603563031214526, "IBRANCE": 1.3891465019539484, "JARDIANCE": 8.881953527636798, "OLANZAPINE": 4.02002232787715, "PEGASYS": 1.307755831606006, "SAXENDA": 67.90899668149329, "SIFROL": 28.259577915258152, "TRULICITY": 8.09562298083101, "ZYPREXA": 7.179228382130544}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3243.json
index 134680809b0..1889b124c2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3243.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3243.json
@@ -1 +1 @@
-{"ELIQUIS": 2.106821336923653, "KEPPRA": 2.5189865058628635, "null": 3.44519585305426}
\ No newline at end of file
+{"null": 2.140409623997833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3244.json
index 9cb41bc2cb4..825c5ff6e25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3244.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3244.json
@@ -1 +1 @@
-{"BOTULINUM": 19.423978655216736, "COMIRNATY": 1.1146271939873778, "COSENTYX": 1.449548379887208, "GARDASIL": 8.632601510921315, "HUMIRA": 4.430173283832537, "IBRANCE": 1.3741459009370234, "PEGASYS": 1.0882138059873638, "SAXENDA": 3.9593160360086697, "SUTENT": 2.046473677958786, "XOLAIR": 1.857192370489176}
\ No newline at end of file
+{"SOLIRIS": 24.626050630017804, "null": 0.6971242164888573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3245.json
index 928d9e682b5..6c370d97070 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3245.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3245.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 3.975919377901615, "HUMALOG": 3.091107502744825, "IBRANCE": 2.4292271148369307, "LANTUS": 2.3034974448165784, "SAXENDA": 7.74825804228397, "SIMPONI": 3.563595338019672, "XELJANZ": 3.262190697031319, "null": 1.1350715525828523}
\ No newline at end of file
+{"ABATACEPT": 2.700149922809108, "ACLIDINIUM": 2.3477185887780525, "ADALIMUMAB": 4.658656223028392, "AFINITOR": 0.1990428028373506, "AIMOVIG": 0.8919661200947834, "AMGEVITA": 23.02394832891432, "AMINOSALICYLIC": 1.4381496193974153, "ARAVA": 1.2324814100590886, "AUBAGIO": 1.027160986835627, "AZATHIOPRINE": 11.94822207666429, "BOTULINUM": 1.9253647216654284, "BUDESONIDE": 4.222573643400962, "CELLCEPT": 0.5615415861081671, "CERTOLIZUMAB": 17.213120896340417, "CHAMPIX": 0.2656752302340582, "CICLOSPORIN": 0.4610438044982077, "CIMZIA": 27.1536418603596, "COMIRNATY": 0.1384193324509296, "COSENTYX": 10.74567174861443, "ELIQUIS": 0.2324156705097497, "ENBREL": 2.5490366837758813, "ENTYVIO": 43.589864520701134, "EXJADE": 0.3389193253396536, "FENTANYL": 2.2384223435634767, "GARDASIL": 0.798330483259428, "HUMALOG": 0.1742015623795945, "HUMIRA": 18.58916965893873, "IBRANCE": 0.182341197094024, "IBUPROFEN": 0.3047162782841692, "IDACIO": 13.828168476310458, "INFLECTRA": 17.04982339734684, "INFLIXIMAB": 21.018014706016675, "JARDIANCE": 0.2279056474621434, "LANTUS": 0.1534889147480215, "MERCAPTOPURINE": 6.482841448367913, "METHOTREXATE": 2.0084742586468023, "MYCOPHENOLATE": 1.0975261900508282, "PANTOPRAZOLE": 2.273804501380179, "PEGASYS": 0.1210656647922691, "PLAVIX": 0.1517951386687981, "REMICADE": 18.39925018668703, "RINVOQ": 3.420913320434586, "RISANKIZUMAB": 54.517793726689206, "ROACTEMRA": 0.3747441276174681, "SAXENDA": 0.8733380793480972, "SIMPONI": 4.200038313002567, "SKYRIZI": 4.497658652437914, "SOLIRIS": 0.522359796467525, "SPIKEVAX": 0.1228923082812238, "STELARA": 107.30726332570543, "SUBOXONE": 0.5802613790658229, "TOZINAMERAN": 0.3329681034241301, "TREMFYA": 0.7559272103526201, "USTEKINUMAB": 20.95645349985838, "VAXZEVRIA": 0.1103879423081095, "VEDOLIZUMAB": 22.84430573938296, "VIAGRA": 0.5671971417221974, "XELJANZ": 2.334997737413759, "XOLAIR": 0.7467147100265128, "ZOSTAVAX": 0.155424518953898, "null": 0.3019595900289255}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3246.json
index ea4f247431f..aa67cb4c5ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3246.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3246.json
@@ -1 +1 @@
-{"COVID19": 1.7283061769311057, "NEXAVAR": 8.308368799274705, "null": 1.1335973019071113}
\ No newline at end of file
+{"ERTAPENEM": 204.75663956831136, "IBUPROFEN": 12.514375501789168, "LEVOFLOXACIN": 5.448960625403972, "null": 5.28362196380449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3247.json
index b68349dd2e2..b62b1fe14db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3247.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3247.json
@@ -1 +1 @@
-{"INVOKANA": 567.3089878642406, "JARDIANCE": 17.529359952492815, "LANTUS": 32.163226016377976}
\ No newline at end of file
+{"DARZALEX": 4305.221030728607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3248.json
index 1ae6b6af97e..5622ab590cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3248.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3248.json
@@ -1 +1 @@
-{"ABATACEPT": 11.857098787093443, "ADALIMUMAB": 11.47907806571818, "AERIUS": 5.604969355190742, "ANAKINRA": 16.127376329404633, "ARAVA": 13.215457919014629, "AVAMYS": 1.6433662913879128, "CELECOXIB": 3.4266784750706885, "CIMZIA": 1.512634153308608, "COMBIVIR": 5.03464370043909, "ENBREL": 8.985730703069285, "EVISTA": 2.9655351865267283, "FORSTEO": 1.0471031704348108, "GARDASIL": 1.4301664729961687, "HUMALOG": 1.4961817628923315, "HUMIRA": 4.500188227793121, "LEFLUNOMIDE": 13.97841201200264, "LEVETIRACETAM": 1.2071344007631064, "LYRICA": 1.691769722782657, "METHOTREXATE": 3.603022210928081, "RINVOQ": 2.1604749295277226, "RITUXIMAB": 1.7773859945256405, "SIMPONI": 3.223295380032265, "XELJANZ": 7.957466409026718, "ZOSTAVAX": 2.3036316008558164}
\ No newline at end of file
+{"CIMZIA": 8.166727712834675, "COMIRNATY": 0.2640799042752145, "SYNAGIS": 95.19822180250073, "null": 1.3886588865424947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3249.json
index 49a7679c8b7..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3249.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3249.json
@@ -1 +1 @@
-{"APIDRA": 2.231357501520031, "ATRIPLA": 26.790592196425827, "AUBAGIO": 1.1430733740971697, "AVANDIA": 1.5093916744293256, "BONVIVA": 2.9904376969671675, "DACLATASVIR": 6.381036602960899, "DARUNAVIR": 3.751483312827532, "EVENITY": 3.732413956682307, "EVISTA": 4.799184072330944, "FAMPYRA": 1.1865177288809896, "FIRDAPSE": 2.887743426747204, "FORSTEO": 2.3599087106467174, "HEPSERA": 5.8403118744172975, "HUMALOG": 2.2030633807493145, "ILARIS": 64.11176941463039, "KALETRA": 2.9285158116091585, "LANTUS": 2.696563210055527, "LEFLUNOMIDE": 2.918000043729168, "LEVEMIR": 1.4230234410910734, "LYRICA": 2.2617666870674014, "MICARDIS": 1.1087232275262138, "OMALIZUMAB": 1.2698619758902647, "REVATIO": 1.3311348512614416, "RITUXIMAB": 2.3166968197252857, "SAXENDA": 1.0544730541532448, "SIMPONI": 1.6031824855064982, "SPINRAZA": 2.061476419417024, "STRIBILD": 13.093899613779907, "SUBOXONE": 2.932384946720534, "TREMFYA": 1.313234979367274, "TRUVADA": 19.006097479218766, "VIAGRA": 1.152084746963875, "VIREAD": 8.63491394805124, "XELJANZ": 3.3521393117748315, "XOLAIR": 1.0151239425751, "XYREM": 2.2089337026026463, "ZOSTAVAX": 1.4786919243857792}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/325.json
index d4768047436..6aa54f1916b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/325.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/325.json
@@ -1 +1 @@
-{"BUDESONIDE": 116.07700445778656, "CICLOSPORIN": 43.93499604294308}
\ No newline at end of file
+{"GONALF": 703.7384510481628, "OVITRELLE": 591.9121127087847, "null": 1.0238351796550105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3250.json
index 2e671075f93..2551d96fc2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3250.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3250.json
@@ -1 +1 @@
-{"ABATACEPT": 6.443164225527807, "ACETYLSALICYLIC": 349.00448361854524, "ADALIMUMAB": 8.578135568763129, "ANAKINRA": 16.853684220720293, "ARAVA": 7.043414607298327, "AUBAGIO": 2.941000834240202, "CIMZIA": 3.3507898573249024, "LANTUS": 8.162022156872656, "RINVOQ": 5.491155492377541, "SIMPONI": 18.31577312161928, "STELARA": 2.586664427906689, "XELJANZ": 7.890907341742226, "ZOSTAVAX": 2.377305263020258}
\ No newline at end of file
+{"null": 0.7251000137213048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3251.json
index 3f4867d3e92..dca3aea6792 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3251.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3251.json
@@ -1 +1 @@
-{"AERIUS": 3003.0361538269094}
\ No newline at end of file
+{"null": 2.5442359161660035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3252.json
index 0b808b9240b..3a12ce8c59a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3252.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3252.json
@@ -1 +1 @@
-{"TELMISARTAN": 2804.388150094649}
\ No newline at end of file
+{"ABILIFY": 1.697758173343726, "AERIUS": 1.5343399286182982, "AIMOVIG": 0.3117480320294375, "ALLI": 15.515090601428962, "APIDRA": 0.7607222533599346, "ARAVA": 0.2924512586638814, "ARIPIPRAZOLE": 1.0346555856393131, "AUBAGIO": 0.4602953050512062, "BENLYSTA": 1.7847256839377208, "BEXSERO": 20.351109644170656, "BRINTELLIX": 4.090818703878639, "BRIVIACT": 2.861174513604004, "BUDESONIDE": 0.1897836191137031, "BUPRENORPHINE": 1.45100867791199, "CHAMPIX": 9.625461237872962, "CICLOSPORIN": 0.1804641090793622, "CIMZIA": 0.0854953460400412, "COMIRNATY": 0.1720383424959127, "COSENTYX": 0.2922643062341322, "CYMBALTA": 4.000194320065611, "ENBREL": 0.8352822749128305, "FASLODEX": 0.3971354218507021, "FENTANYL": 0.5860513165646191, "FORSTEO": 0.4040427594844393, "FYCOMPA": 3.5096254075168702, "GARDASIL": 1.5149615476888645, "HEXACIMA": 92.69704863735092, "HEXYON": 27.83776619680601, "HUMALOG": 0.3405991454271919, "IBRANCE": 0.7640989532796191, "INFANRIX": 39.1497193301867, "KAFTRIO": 1.6444529766745242, "KEPPRA": 2.306183885617688, "LANTUS": 0.4191217501223481, "LATUDA": 5.782061130491279, "LEVETIRACETAM": 1.2539091234564157, "LEVOFLOXACIN": 0.382306185002751, "LYRICA": 1.8416091862642987, "MENVEO": 1.7937796993435149, "METHOTREXATE": 0.2405930124539765, "MIDAZOLAM": 1.0113447906178965, "MMRVAXPRO": 49.1845845369857, "NAGLAZYME": 1.9184875345151116, "NIMENRIX": 7.762347387416658, "NON": 35.76743583956051, "NOT": 4.116362532232704, "NUCALA": 0.4187478770519423, "OCRELIZUMAB": 0.9535147553612956, "OLANZAPINE": 0.5218747575677523, "OMALIZUMAB": 1.0600948021205572, "PANTOPRAZOLE": 0.6432145501816802, "PEGASYS": 2.000921207935645, "PEGINTERFERON": 0.6736933723442247, "PEGINTRON": 1.0908288598658435, "PREVENAR": 30.84094324764328, "RIBAVIRIN": 0.466991249222866, "ROTARIX": 49.98426336553884, "ROTATEQ": 42.32100871779234, "SAXENDA": 0.8465724606028873, "SHINGRIX": 0.2320809669080052, "SPIKEVAX": 0.1479373863800368, "STELARA": 0.2272371374164552, "SUBOXONE": 2.9999084818954165, "SUTENT": 0.1729379673189876, "SYNAGIS": 12.57632252229386, "SYNFLORIX": 9.757838990373523, "TAMIFLU": 2.540461978700807, "TOZINAMERAN": 0.8882393976472783, "TWINRIX": 1.0114072510695598, "VAXZEVRIA": 0.2713125860709037, "VIMPAT": 0.6848716182082347, "XELJANZ": 0.3593353766242638, "XOLAIR": 0.8584173277040221, "XYREM": 1.3496054643662858, "ZOSTAVAX": 0.3124760513563441, "ZYPREXA": 0.8350505585470647, "null": 2.015274953491129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3253.json
index 2eaa598f27b..1dcbba7ed2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3253.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3253.json
@@ -1 +1 @@
-{"null": 1.53567740245871}
\ No newline at end of file
+{"COMIRNATY": 0.2237339735119746, "HARVONI": 30.674879948406403, "PEGASYS": 21.537640796997987, "PEGINTERFERON": 27.820140695207844, "PEGINTRON": 28.02724341520697, "RIBAVIRIN": 40.89345089828407, "null": 0.3465920681439638}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3254.json
index 8abc4452054..e292470a594 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3254.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3254.json
@@ -1 +1 @@
-{"AVAMYS": 176.72227183573497, "ESOMEPRAZOLE": 153.74561439498896, "MEPOLIZUMAB": 53.1521762333382}
\ No newline at end of file
+{"OMALIZUMAB": 166.3342951205246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3255.json
index 48c7a2445da..b30067de1a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3255.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3255.json
@@ -1 +1 @@
-{"ANORO": 131.26424118667836, "APIXABAN": 45.11370910207286, "AVAMYS": 29.0509482766136, "AZATHIOPRINE": 19.321465843131357, "BUDESONIDE": 4.436987903468998, "CICLOSPORIN": 1.641077632430669, "FASENRA": 14.035157058805105, "KAFTRIO": 40.29183501070369, "KALYDECO": 39.84352076104096, "MEPOLIZUMAB": 5.025501050625416, "NUCALA": 10.266101818017672, "OMALIZUMAB": 158.16842441219603, "ORKAMBI": 210.98520079574155, "TOBI": 189.36367883747508, "XOLAIR": 29.310949396213665}
\ No newline at end of file
+{"null": 1.5854742411385632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3256.json
index 0761071a69f..04d446d71ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3256.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3256.json
@@ -1 +1 @@
-{"COVID19": 3.019958881676571, "NUCALA": 101.09095623438807}
\ No newline at end of file
+{"null": 0.489587685703479}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3257.json
index 64cf258765d..387ae792cb6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3257.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3257.json
@@ -1 +1 @@
-{"OMALIZUMAB": 287.485391582833}
\ No newline at end of file
+{"BUDESONIDE": 10.468026461528035, "CELLCEPT": 16.15380623465438, "CICLOSPORIN": 21.660995820214723, "DEXAMETHASONE": 17.664675414895513, "EFAVIRENZ": 77.55549317154102, "LAMIVUDINE": 67.57234709249312, "MYCOPHENOLATE": 49.16147166318974, "null": 0.3128942970871197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3258.json
index bd56fee0296..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3258.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3258.json
@@ -1 +1 @@
-{"BUDESONIDE": 10.345550596987223, "ESBRIET": 65.95745051705178, "FLUTICASONE": 277.4831182391939, "NUCALA": 33.55650450346649, "OFEV": 89.14292732257697, "OMALIZUMAB": 45.86172568126258, "PIRFENIDONE": 405.76837801449045, "TELMISARTAN": 311.63286284412646}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3259.json
index 6200bfe24d8..975f1922556 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3259.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3259.json
@@ -1 +1 @@
-{"ATRIPLA": 15.183971852453237, "TRUVADA": 12.351142054677586}
\ No newline at end of file
+{"ASPARAGINASE": 34.921023865416814, "COMBIVIR": 27.51490976451842, "KALETRA": 10.590789774317493, "KEPPRA": 6.459208641424974, "null": 3.843201908394765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/326.json
index 202c4e32940..0d265089b9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/326.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/326.json
@@ -1 +1 @@
-{"ATRIPLA": 17.917449050920517}
\ No newline at end of file
+{"BYETTA": 48.555329636039154, "JANUMET": 40.575826807618526, "null": 0.8985840552088098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3260.json
index 912919a76b3..04659610278 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3260.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3260.json
@@ -1 +1 @@
-{"ELIQUIS": 6.773449635607992, "LANTUS": 10.173637361600765, "null": 1.2695512018029946}
\ No newline at end of file
+{"ABACAVIR": 40.31127095948433, "CICLOSPORIN": 22.815275418123303, "null": 0.186065188959828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3261.json
index 8d0834e2bc6..4de4a254bec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3261.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3261.json
@@ -1 +1 @@
-{"null": 5.664074894467893}
\ No newline at end of file
+{"AVAMYS": 382.5963360974045, "null": 0.1896518358400421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3262.json
index 70ed6ed3180..30ffbe9a2cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3262.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3262.json
@@ -1 +1 @@
-{"HUMIRA": 631.1768025196184}
\ No newline at end of file
+{"null": 3.68831327018173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3263.json
index aeea8136b40..b3bb880a113 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3263.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3263.json
@@ -1 +1 @@
-{"EYLEA": 88.51253366194975, "null": 1.5594716183690884}
\ No newline at end of file
+{"LEVOFLOXACIN": 33.975780759898925, "null": 2.43724339145218}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3264.json
index ab1ea607837..db318d20cd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3264.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3264.json
@@ -1 +1 @@
-{"null": 3.112300009500563}
\ No newline at end of file
+{"null": 1.3199170279832728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3265.json
index 3a9a84b3b34..f3dbaf57a7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3265.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3265.json
@@ -1 +1 @@
-{"null": 9.248258253748087}
\ No newline at end of file
+{"ALEMTUZUMAB": 146.825592127018, "null": 1.1700823109215273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3266.json
index 3f7d6c4a550..17d8bb3b97b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3266.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3266.json
@@ -1 +1 @@
-{"HUMIRA": 36.11607921342855, "null": 2.962524686275257}
\ No newline at end of file
+{"CRIXIVAN": 193.18415333382933, "null": 3.132849669370765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3267.json
index 81523f99345..131c89517f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3267.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3267.json
@@ -1 +1 @@
-{"BRAFTOVI": 6.902869377386941, "COMTAN": 14.564890833762073, "IBRANCE": 5.245087393472557, "RELVAR": 22.69287823451069, "TRELEGY": 33.04145542965983, "XTANDI": 23.56750391630196, "null": 4.211819422326996}
\ No newline at end of file
+{"COMIRNATY": 1.0936669079349013, "CYMBALTA": 18.454830062797036}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3268.json
index 624170e33ad..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3268.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3268.json
@@ -1 +1 @@
-{"null": 1.731601702195374}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3269.json
index 368a76a3861..f86bd390d57 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3269.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3269.json
@@ -1 +1 @@
-{"FENTANYL": 49.784648327956766, "null": 1.29554158417237}
\ No newline at end of file
+{"null": 1.2303781116536314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/327.json
index e6075d82a86..1e5b86c3084 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/327.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/327.json
@@ -1 +1 @@
-{"OMALIZUMAB": 318.7836480658726}
\ No newline at end of file
+{"null": 1.6707413842154883}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3270.json
index 8f3437005ec..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3270.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3270.json
@@ -1 +1 @@
-{"BEOVU": 26.226150408941898, "EYLEA": 43.33124274476269, "NEPAFENAC": 629.2321277083585, "NEVANAC": 270.04463671168526, "OMALIZUMAB": 5.035664043668312, "ZOSTAVAX": 2.1563545715424257, "null": 1.726406269633321}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3271.json
index bbd178ae319..26ee34bfad8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3271.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3271.json
@@ -1 +1 @@
-{"BRINTELLIX": 3.198366619658688, "BUPIVACAINE": 3.843513565322045, "CHAMPIX": 1.3306227832359174, "COMIRNATY": 1.6643313554294763, "CYMBALTA": 1.68830430827012, "FORSTEO": 1.4700662862279257, "GARDASIL": 1.135900346463136, "LYRICA": 1.02560519428129, "SIMPONI": 1.038984067803964, "SUBOXONE": 2.823693538096489, "TWINRIX": 7.460690967269573, "VAXZEVRIA": 1.412242875909951, "XELODA": 4.762352058622428, "null": 1.4393818567596832}
\ No newline at end of file
+{"null": 0.6192836920493578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3272.json
index 5398542342b..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3272.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3272.json
@@ -1 +1 @@
-{"ASPARAGINASE": 3.75999569342926, "AVASTIN": 4.595623332618251, "BEVACIZUMAB": 6.003617912462157, "EMPAGLIFLOZIN": 113.05436512855135, "FORXIGA": 83.95445172046969, "INVOKANA": 29.700321249119792, "JARDIANCE": 527.484459202583, "ROACTEMRA": 2.513871438874748}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3273.json
index e52a42b079d..5c9df36d017 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3273.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3273.json
@@ -1 +1 @@
-{"CHOLESTAGEL": 13346.819653084816}
\ No newline at end of file
+{"AZATHIOPRINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3274.json
index 7d00bda8fe9..53bc4ceb45d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3274.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3274.json
@@ -1 +1 @@
-{"ATRIPLA": 25.28911419457833, "AVANDIA": 2.406422488438323, "BONVIVA": 6.166452749831576, "COMTAN": 1.737320038930249, "EVENITY": 110.43387424951868, "EVISTA": 15.034191178847802, "FASLODEX": 1.639927295831549, "FESOTERODINE": 14.77680835255884, "FORSTEO": 3.5924614077263577, "FULVESTRANT": 1.2328808232728503, "HEPSERA": 10.55615778216707, "JAKAVI": 1.0019917555210354, "KALETRA": 11.153506224471576, "LYNPARZA": 1.031714963651826, "MICARDIS": 1.0527707702742903, "MIRCERA": 2.00521205189836, "RINVOQ": 1.66744912078776, "STALEVO": 5.769176202321302, "STRIBILD": 24.913703256263304, "TAGRISSO": 2.645747600499752, "TRUVADA": 25.590753011490605, "VIREAD": 11.318158613347029, "XELJANZ": 1.673136266157487, "XOFIGO": 2.385889912485718, "XTANDI": 2.0313533656356904}
\ No newline at end of file
+{"GARDASIL": 6.300343591545618, "JARDIANCE": 9.685750187682151, "LEVETIRACETAM": 20.55012709141713, "null": 0.9273743960147672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3275.json
index a0673462484..314e55022cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3275.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3275.json
@@ -1 +1 @@
-{"ADALIMUMAB": 22.766146766580864}
\ No newline at end of file
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3276.json
index d67a8cae467..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3276.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3276.json
@@ -1 +1 @@
-{"null": 1.070213856071489}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3277.json
index a024fac5747..450b4fd133c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3277.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3277.json
@@ -1 +1 @@
-{"FORSTEO": 35.04906616736135, "null": 1.0467952876946884}
\ No newline at end of file
+{"null": 1.4631329108364377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3278.json
index 10080780807..6309776f519 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3278.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3278.json
@@ -1 +1 @@
-{"VIAGRA": 18.65750474614494, "null": 18.168891145059757}
\ No newline at end of file
+{"ADALIMUMAB": 0.7360103424144144, "ATAZANAVIR": 59.00350200062468, "AVAMYS": 7.745835116607092, "BUDESONIDE": 15.406352189259524, "CICLOSPORIN": 2.189364500102808, "COBICISTAT": 128.47280675885344, "COMIRNATY": 0.0407152664050827, "DARUNAVIR": 19.120494904902607, "DEXAMETHASONE": 2.301918980296583, "FLUTICASONE": 27.994461255010663, "GENVOYA": 58.80559164885881, "HYDROCORTISONE": 23.646301883744197, "ISENTRESS": 11.220977766039065, "KALETRA": 47.3937118305524, "LOPINAVIR": 105.97640135108598, "MEPOLIZUMAB": 4.068204217798504, "NORVIR": 147.495289442233, "REYATAZ": 14.802245477305148, "RITONAVIR": 475.6644080728068, "STRIBILD": 1.4557653095136922, "null": 1.3629631798289523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3279.json
index 87db0a80e10..842725e34ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3279.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3279.json
@@ -1 +1 @@
-{"ATRIPLA": 4.322916990169276, "FORSTEO": 29.293571628827525}
\ No newline at end of file
+{"ADALIMUMAB": 3.217221915307109, "ARAVA": 0.5720997208257549, "ATAZANAVIR": 29.337088879657284, "AZATHIOPRINE": 5.45007388978423, "BUDESONIDE": 7.703342063386803, "CELLCEPT": 4.763727828644067, "CICLOSPORIN": 9.241536696658327, "ENTYVIO": 16.900483375084338, "HYDROCORTISONE": 6.186301484113043, "KALETRA": 15.805306307783368, "LOPINAVIR": 69.2044289190311, "MEPOLIZUMAB": 13.052922153355247, "METHOTREXATE": 6.299573535337026, "MYCOPHENOLATE": 9.505314501869144, "NORVIR": 70.86810849352483, "NUCALA": 5.546616085944048, "RITONAVIR": 123.73437360705206, "null": 1.2338936463553778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/328.json
index 7c088b82485..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/328.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/328.json
@@ -1 +1 @@
-{"ANAKINRA": 135.4513938645052, "CICLOSPORIN": 23.646736010988448, "JAKAVI": 60.10570643809699}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3280.json
index a280ce3e2a2..93c0f18c97a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3280.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3280.json
@@ -1 +1 @@
-{"ATRIPLA": 10.8046082759269, "IRBESARTAN": 45.02893113078954, "LANTUS": 3.616584980095454, "STRIBILD": 7.70458096946798, "TRUVADA": 3.232855366542165}
\ No newline at end of file
+{"CICLOSPORIN": 19.73575025863475, "CIMZIA": 4.55586961985208, "COMIRNATY": 0.1361541760964164, "COSENTYX": 7.429001287089465, "RINVOQ": 19.79352519504253, "SIMPONI": 3.8919490181914447, "STELARA": 13.054535187216883, "TREMFYA": 16.967214135582303, "null": 0.6702865280282765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3281.json
index 63bbbf21c06..18a637bda11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3281.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3281.json
@@ -1 +1 @@
-{"AFINITOR": 9.769904617971568, "ATRIPLA": 9.074323540278211, "FORSTEO": 19.424240771987712, "TRUVADA": 6.520159988183859}
\ No newline at end of file
+{"HUMALOG": 55.94232430957943, "INSULIN": 166.3607393250529, "LANTUS": 43.80142730973982}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3282.json
index 0aeff180e82..60dbfd4175f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3282.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3282.json
@@ -1 +1 @@
-{"AZILECT": 251.44086568418496, "CARBIDOPA": 195.7571714141756, "COMTAN": 67.19127695877536, "COVID19": 7.947572575735706, "STALEVO": 69.77136538612962}
\ No newline at end of file
+{"LEVOFLOXACIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3283.json
index a7024c4b60b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3283.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3283.json
@@ -1 +1 @@
-{"ADALIMUMAB": 12.153282138137984, "AFINITOR": 2.0952357970050968, "ALIGN": 106.10161277887882, "AMINOSALICYLIC": 65.57882864305256, "AUBAGIO": 2.241297862085012, "AVAMYS": 28.91480097318433, "AZATHIOPRINE": 2.621922347805954, "BUDESONIDE": 40.49133881938085, "CELECOXIB": 3.591085642591316, "CIMZIA": 1.6629265524632235, "ENTYVIO": 28.086848544392943, "ESOMEPRAZOLE": 2.0136444136330525, "EXJADE": 1.0120361797727542, "HUMIRA": 15.288560856269516, "INFLECTRA": 14.505363748733272, "INFLIXIMAB": 35.87700965493708, "JANUMET": 1.0953933854482518, "OFEV": 1.728475731436441, "PANTOPRAZOLE": 3.66422873196264, "PREGABALIN": 16.29850977187622, "REMICADE": 8.336665048231776, "REMSIMA": 24.48324583090658, "RINVOQ": 3.701705741691852, "ROTATEQ": 4.446760420273724, "SIMPONI": 2.156486340711426, "STELARA": 3.614095293989173, "SUTENT": 1.33929566737406, "TEDUGLUTIDE": 42.81589314851118, "VEDOLIZUMAB": 17.89618934955584, "XELJANZ": 10.3280252432236}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3284.json
index d67a8cae467..91a24f8fa0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3284.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3284.json
@@ -1 +1 @@
-{"null": 1.070213856071489}
\ No newline at end of file
+{"CASPOFUNGIN": 623.8498639281297, "null": 0.7163965810284204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3285.json
index 51640854325..3da59600997 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3285.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3285.json
@@ -1 +1 @@
-{"null": 1.793046385559705}
\ No newline at end of file
+{"VORICONAZOLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3286.json
index 406286f3903..731a739207a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3286.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3286.json
@@ -1 +1 @@
-{"null": 1.7536218077500911}
\ No newline at end of file
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3287.json
index 259a2785e8c..c079965f928 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3287.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3287.json
@@ -1 +1 @@
-{"AUBAGIO": 2.3564022222904524, "AVAMYS": 19.756671911972173, "CHAMPIX": 4.082880585803816, "CYMBALTA": 1.6979680931146, "ENBREL": 4.007564142364574, "ESBRIET": 2.8389036981061, "FASENRA": 3.493919857149636, "GARDASIL": 1.1312642246039888, "HUMALOG": 1.753917592972459, "IBRANCE": 1.4347478558737463, "KEPPRA": 3.2637170954778822, "LANTUS": 2.05161792987045, "LATUDA": 5.47558127092253, "LEFLUNOMIDE": 16.532099030372613, "LEVETIRACETAM": 1.6168598597448476, "LYRICA": 1.9327120071709287, "MEPOLIZUMAB": 2.8992863653286145, "OLANZAPINE": 4.37571448607221, "OMALIZUMAB": 10.279502156514525, "PEGINTRON": 1.109943457636979, "RINVOQ": 2.611825415051352, "TRELEGY": 2.3497400465445595, "VIAGRA": 2.4516875379082688, "XELJANZ": 2.380511762342302, "XOLAIR": 3.0572908959121645, "ZOSTAVAX": 2.817179626055943, "null": 1.6711600051679518}
\ No newline at end of file
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3288.json
index 3ce9056a788..fbd147bbe37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3288.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3288.json
@@ -1 +1 @@
-{"COVID19": 1.9563649083217247, "GARDASIL": 12.471320486033791, "SPIKEVAX": 12.740736311781546}
\ No newline at end of file
+{"BENLYSTA": 18.58318381084857, "COMIRNATY": 0.1787710851302904, "IBRANCE": 3.232365257244432, "STELARA": 5.862898291641224, "null": 1.2196575827118856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3289.json
index f129c28e26e..e102b651352 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3289.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3289.json
@@ -1 +1 @@
-{"ACLIDINIUM": 13.226810655026258, "AFINITOR": 1.050196012058377, "ALENDRONATE": 46.19825742893999, "ANORO": 35.23152165012163, "APIXABAN": 23.974572012323087, "ARANESP": 1.3247116837475372, "AVAMYS": 47.969754872292114, "AZATHIOPRINE": 4.928296576220172, "AZOPT": 37.54490072368649, "BENRALIZUMAB": 83.59629902439153, "BOSULIF": 2.481239568516834, "BUDESONIDE": 34.05147075057828, "CANAGLIFLOZIN": 63.30852326924861, "CELECOXIB": 1.8940499126844603, "CLOPIDOGREL": 1.0936619310958782, "DAXAS": 44.69104487310736, "DESLORATADINE": 8.439381944953862, "DEXAMETHASONE": 2.0046528464244373, "DUAKLIR": 52.760914489237024, "DUPIXENT": 3.3888005614164407, "ESOMEPRAZOLE": 1.6317684778927282, "EXJADE": 1.2825102233539076, "FASENRA": 1.485165859535026, "FASLODEX": 4.858722266135065, "FLUTICASONE": 21.597496654113343, "FULVESTRANT": 2.3037884716534367, "GLYCOPYRRONIUM": 66.17129266597702, "IBRANCE": 15.27260410172254, "ICLUSIG": 2.176171772150969, "INCRUSE": 7.719024628920669, "INVOKANA": 6.299675955740804, "IRON": 2.4058601826710504, "JAKAVI": 4.174938442858459, "KISQALI": 1.2227759288841364, "LIRAGLUTIDE": 88.59674363071399, "LONSURF": 6.023692379471247, "LYNPARZA": 2.135613311109175, "MEPOLIZUMAB": 30.025746739401605, "NEULASTA": 3.829320361628729, "NINLARO": 2.5888930296866453, "NUCALA": 48.52047214251426, "OMALIZUMAB": 7.521377292703174, "OPSUMIT": 1.0865281078261286, "OZEMPIC": 9.595250146917904, "PANTOPRAZOLE": 6.221342804685814, "PEGASYS": 2.665764304262987, "PLEGRIDY": 4.917956368957904, "PREGABALIN": 3.678880157178435, "REBETOL": 1.8755685764102328, "REVLIMID": 1.7287417580773572, "RUBRACA": 11.69700743732657, "SOLIRIS": 1.6527755414927028, "SUTENT": 1.6793668511702466, "TASIGNA": 1.0086666569288532, "TELMISARTAN": 5.310903785908307, "UMECLIDINIUM": 36.34621002572706, "VARENICLINE": 19.295760722661964, "XOFIGO": 6.235813645803122, "XOLAIR": 1.1950237916814883}
\ No newline at end of file
+{"ARAVA": 1.312173070187013, "COMIRNATY": 0.3103127250845243, "KEYTRUDA": 5.050868227443964, "MEKINIST": 15.398057463042177, "PEGASYS": 8.232388210848448, "PEGINTERFERON": 80.12832841453931, "PEGINTRON": 8.350869435698465, "REBETOL": 70.93362642569758, "RIBAVIRIN": 49.87616868919748, "null": 0.1159069875349497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/329.json
index 9b6036c71cd..0a333d07d66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/329.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/329.json
@@ -1 +1 @@
-{"IRINOTECAN": 809.095363387587}
\ No newline at end of file
+{"null": 0.8839493325626656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3290.json
index 9e221de3be2..b7a2ebdac24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3290.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3290.json
@@ -1 +1 @@
-{"AFINITOR": 1.0271796517083225, "ALIMTA": 1.2578819151628629, "AVASTIN": 1.7740082934893693, "AZACITIDINE": 4.470106748047323, "BEVACIZUMAB": 1.5688908457586757, "BOSULIF": 3.233179046733889, "CYTARABINE": 2.756190249461182, "DEXAMETHASONE": 4.7653327088863815, "DOCETAXEL": 1.3277049241250862, "ELIQUIS": 1.351257369048138, "EXJADE": 3.914746158348806, "FASLODEX": 6.017903672628327, "FULVESTRANT": 3.764609736582575, "IBRANCE": 42.48325290401619, "ICLUSIG": 3.9702374987291673, "JAKAVI": 6.866002485008272, "KYMRIAH": 11.05449778336716, "LYNPARZA": 2.628132873229284, "MABTHERA": 6.508644197216642, "MEKINIST": 1.429729774343062, "NEULASTA": 1.6884069655847629, "NINLARO": 24.739155655112604, "PEGASYS": 8.724457781966105, "PEGINTERFERON": 1.248062285494382, "PEGINTRON": 1.8937542893391224, "REVLIMID": 38.37444031328932, "RITUXIMAB": 1.623599726655067, "SPRYCEL": 12.560052394155456, "SUTENT": 2.001672263402399, "TASIGNA": 4.369976028996687, "VFEND": 1.0402685176887836, "XTANDI": 3.4862464490880787, "null": 1.644931154688878}
\ No newline at end of file
+{"null": 1.913393433494604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3291.json
index db1bbe64120..df678323402 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3291.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3291.json
@@ -1 +1 @@
-{"GARDASIL": 33.72115178371756, "SPIKEVAX": 9.196383097252456}
\ No newline at end of file
+{"COMIRNATY": 0.5319206601495129, "COSENTYX": 6.214344907375711, "IRESSA": 34.78099360469639, "KEYTRUDA": 3.743459729134848, "SPIKEVAX": 0.4572144221576926, "VAXZEVRIA": 0.1474670155044605, "null": 0.8848605379634279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3292.json
index 74ea46e1c6c..0318adf34b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3292.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3292.json
@@ -1 +1 @@
-{"IPILIMUMAB": 51.11545576917631, "KEYTRUDA": 117.9888966304432, "OPDIVO": 176.56552251434485, "PEMBROLIZUMAB": 35.50521286446824}
\ No newline at end of file
+{"ADALIMUMAB": 0.2093498358522123, "APIDRA": 1.8294184816644028, "APROVEL": 11.179387334071526, "ARANESP": 0.8893047527749094, "ARAVA": 0.2986342202698487, "BYDUREON": 1.235025774666166, "CIMZIA": 0.7663602778321362, "CLOPIDOGREL": 0.9512883259601008, "COMIRNATY": 0.4658408365821939, "COSENTYX": 2.5024581128759285, "CUBICIN": 7.300895969521969, "ELIQUIS": 2.32445560810124, "ENTYVIO": 3.0065813612344474, "ESOMEPRAZOLE": 3.151134897988244, "EXJADE": 1.4975590330192294, "GARDASIL": 0.4553090876001722, "HUMIRA": 1.2178588365928942, "INCIVO": 2.1099434692166, "IPILIMUMAB": 5.026146201745092, "JANUVIA": 1.5796957348648937, "JARDIANCE": 0.6904230848831983, "KEPPRA": 0.6977369701460453, "KEYTRUDA": 0.4325846173467962, "LEVOFLOXACIN": 1.2287938580081856, "LITAK": 84.4335224071629, "METHOTREXATE": 0.9555483365716811, "MODERNA": 0.7852052160582189, "NEXAVAR": 1.559962754245936, "NOVONORM": 8.597949967501325, "PEGASYS": 0.3694509883886745, "PEGINTERFERON": 2.0604717485991317, "PREGABALIN": 4.224032468053808, "RITUXIMAB": 1.7489295336645925, "ROACTEMRA": 5.665131496528173, "SIMPONI": 4.107385103605791, "SPIKEVAX": 0.2503221058310463, "STELARA": 3.269576169792827, "TAGRISSO": 3.395635663936643, "THALIDOMIDE": 5.137814944953071, "TOZINAMERAN": 0.5731926037234455, "VAXZEVRIA": 0.385984396257079, "XOLAIR": 1.5044117649125406, "null": 1.769073928085609}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3293.json
index 271de9f4d3d..c5a2544b728 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3293.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3293.json
@@ -1 +1 @@
-{"null": 1.607526672628602}
\ No newline at end of file
+{"ALEMTUZUMAB": 163.0864917968889, "null": 0.4772793874135558}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3294.json
index 0cd2c724d94..523f18bf14c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3294.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3294.json
@@ -1 +1 @@
-{"ACETYLSALICYLIC": 328.6286408623495, "AIMOVIG": 1.6510983237051722, "ARAVA": 2.3804125527506703, "AUBAGIO": 3.326735835569292, "BENLYSTA": 2.9791718978037025, "BORTEZOMIB": 30.08609264414136, "CHAMPIX": 1.3352896803341787, "FENTANYL": 19.151315494064114, "GARDASIL": 1.4727355021543735, "IBRANCE": 1.3446168398180782, "JANUMET": 2.341530866193384, "PEGASYS": 1.0647837019598947, "PLAVIX": 1.3749720971108146, "SUTENT": 1.606842914942154, "XELJANZ": 2.277295271903678, "ZOSTAVAX": 1.4238688524345184, "null": 1.1338455626241624}
\ No newline at end of file
+{"null": 2.1526103969026127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3295.json
index cf6abfd1da3..167145b0499 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3295.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3295.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 14.060997500515118, "AMIKACIN": 73.55685619394276, "ASPARAGINASE": 18.50180720157124, "AZACITIDINE": 27.554173674062927, "BUSULFAN": 30.66480484081361, "CANCIDAS": 100.61353957184764, "CASPOFUNGIN": 207.0090693552395, "CELLCEPT": 7.542394900674092, "CICLOSPORIN": 8.0409854190027, "CYTARABINE": 32.423125896178675, "POSACONAZOLE": 63.97711774661576, "VORICONAZOLE": 17.673646397854935}
\ No newline at end of file
+{"VIAGRA": 706.0198119716691, "null": 0.3773243347746635}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3296.json
index a0459cd434b..6ff2dd94200 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3296.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3296.json
@@ -1 +1 @@
-{"JARDIANCE": 111.008593410883}
\ No newline at end of file
+{"ABILIFY": 0.29112343163151, "AERIUS": 1.5067251516235474, "AFINITOR": 0.5771089917310789, "AIMOVIG": 0.2637123203479339, "AMIKACIN": 1.6795446265960483, "ASPARAGINASE": 0.9610701782589882, "AVASTIN": 0.466446575111562, "BEXSERO": 12.320032584541512, "BOSENTAN": 6.181475762612402, "BRIDION": 4.183342742220885, "BUDESONIDE": 1.2700073843267636, "BUPIVACAINE": 4.439708316568066, "BUPRENORPHINE": 0.7998877623241823, "CAELYX": 3.905814382529029, "CHAMPIX": 0.2708806995897668, "CICLOSPORIN": 0.1479129276670624, "CLOPIDOGREL": 0.7329446699839189, "COMIRNATY": 0.4788396134085911, "CYMBALTA": 0.1169466208803515, "DARZALEX": 0.8621142258944027, "DEXAMETHASONE": 1.0680578421450306, "DULOXETINE": 0.6731969878087571, "ELIQUIS": 0.3646230961737292, "ENOXAPARIN": 3.4746642989756, "EXFORGE": 0.5112378528946631, "FENTANYL": 2.8841627656903768, "FLEBOGAMMA": 11.465153343563037, "GARDASIL": 1.7335019718686249, "HERCEPTIN": 0.8063350828965006, "HEXYON": 11.403233578709486, "HUMAN": 1.5099468617677116, "HYDROCORTISONE": 1.0952628920931642, "IBUPROFEN": 0.4789309289350532, "INFANRIX": 11.90349966003483, "IRBESARTAN": 1.3370269504111645, "KALETRA": 1.7900540091298347, "KEPPRA": 0.7554073659434714, "KEYTRUDA": 0.2358704124952141, "KIOVIG": 11.354928345991318, "LANTUS": 0.2060749087314312, "LEVETIRACETAM": 0.5241277305723304, "LEVOFLOXACIN": 0.8698606367523796, "MENVEO": 2.183137620277801, "MIDAZOLAM": 2.123042919345576, "MIRCERA": 2.059332255584263, "MMRVAXPRO": 3.8544488244521657, "NAGLAZYME": 14.113159405911516, "NEXAVAR": 0.2125094282101546, "NIMENRIX": 2.7339146832721126, "NOT": 4.384247631892458, "NUCALA": 0.4749186901566597, "OLANZAPINE": 0.9094022285005648, "ONCASPAR": 3.650088132871653, "OPSUMIT": 0.9421439718233868, "PEGASYS": 0.2087690331558479, "PEGINTRON": 0.3509957609643209, "POPPERS": 17.35906028025996, "PREGABALIN": 1.807551798854736, "PREVENAR": 14.627333361385306, "PRIVIGEN": 4.116004096684859, "PROPRANOLOL": 2.6790872841584306, "RISPERIDONE": 3.040235704421174, "ROACTEMRA": 0.9170612277072387, "ROTARIX": 38.878018963489815, "ROTATEQ": 5.362106778833264, "SEEBRI": 17.00310165471342, "SHINGRIX": 0.2824564859472671, "SILDENAFIL": 1.7943149423521494, "SPIKEVAX": 0.3209686230276602, "SPINRAZA": 1.472301000541385, "STELARA": 0.1593471485118913, "SUBOXONE": 0.6605363158216004, "SUFENTANIL": 3.113441726415781, "SUTENT": 0.1164666139026925, "SYNAGIS": 17.84650893129187, "SYNFLORIX": 15.047732238951893, "TAMIFLU": 0.5398668726823991, "TOZINAMERAN": 0.4663526832825709, "TRACLEER": 3.1980960721329104, "TWINRIX": 1.850182692775845, "VAXZEVRIA": 0.7142123970422396, "XOLAIR": 0.7893906390732245, "ZYPREXA": 0.6119440103926292, "null": 2.9551221851333627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3297.json
index 574053e6cc5..a78148e4c38 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3297.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3297.json
@@ -1 +1 @@
-{"JARDIANCE": 95.33047787754155}
\ No newline at end of file
+{"MMRVAXPRO": 24.479392325066605, "null": 2.8675163795678484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3298.json
index dc72c69e68f..8b6838a09a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3298.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3298.json
@@ -1 +1 @@
-{"ACLIDINIUM": 3630.822227419112}
\ No newline at end of file
+{"null": 4.439115791972325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3299.json
index 58c0b96f40c..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3299.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3299.json
@@ -1 +1 @@
-{"CASPOFUNGIN": 385.0219473762471}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/33.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/33.json
index af6de81bd81..49c0767e355 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/33.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/33.json
@@ -1 +1 @@
-{"null": 4.269330168075982}
\ No newline at end of file
+{"ABACAVIR": 4.55206955826119, "AFINITOR": 6.468144606178311, "CICLOSPORIN": 5.345096473876784, "CYTARABINE": 6.648450219714082, "ENOXAPARIN": 37.56341374531959, "ROTATEQ": 39.91776686321335, "SUTENT": 0.956853098878544, "ZOSTAVAX": 4.012393880462157, "null": 0.7072200995396722}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/330.json
index d861c52556d..1129bbf9553 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/330.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/330.json
@@ -1 +1 @@
-{"PAZOPANIB": 2393.722277868474, "SUTENT": 15.9222770164308}
\ No newline at end of file
+{"ACE": 3589.959076313897, "null": 1.1246258934910878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3300.json
index aef4ce0f851..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3300.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3300.json
@@ -1 +1 @@
-{"XELJANZ": 8.168131865810603}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3301.json
index b0c341b18f2..f3a5b6ad808 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3301.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3301.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 3.922881657236138, "ASPARAGINASE": 16.987797997497495, "AUBAGIO": 1.5040094621659663, "AZACITIDINE": 8.866809752405775, "AZATHIOPRINE": 2.144788536151914, "BENLYSTA": 1.2604914195282024, "BUDESONIDE": 1.7743145151964497, "BUSULFAN": 6.104814002210159, "CANCIDAS": 19.84928634932561, "CARMUSTINE": 7.79750429337409, "CASPOFUNGIN": 22.41872311631253, "CELLCEPT": 2.497603907609301, "CICLOSPORIN": 5.267264077082234, "CIMZIA": 3.254772315692148, "COMBIVIR": 1.9690660727880245, "COSENTYX": 5.684832874673858, "CRESEMBA": 9.34074022540293, "CYTARABINE": 6.771285987602036, "DEXAMETHASONE": 1.8012560736192873, "ESOMEPRAZOLE": 3.241946779004328, "FASLODEX": 1.0815732146437214, "FILGRASTIM": 2.776055475040984, "FORXIGA": 21.74862464924447, "GANCICLOVIR": 7.120198380440874, "HIZENTRA": 2.010865237939614, "HUMALOG": 1.2694304457967338, "HUMIRA": 2.86110139676079, "HYDROCORTISONE": 3.5296089246069364, "IBRANCE": 1.1835530982638045, "ICLUSIG": 1.4330502825708342, "INVOKANA": 5.835271486718919, "JAKAVI": 1.0395391294462966, "JANUVIA": 1.2421872517437744, "JARDIANCE": 37.47873351420503, "KAFTRIO": 1.321633106629126, "MEPOLIZUMAB": 5.48827309614363, "METHOTREXATE": 4.672353284830303, "MYCAMINE": 12.813244983492597, "MYCOPHENOLATE": 8.881537006431833, "NOXAFIL": 8.594273963669927, "OFEV": 1.3373485250940196, "PEGINTRON": 1.416188180380104, "POSACONAZOLE": 22.57499820058748, "RELVAR": 1.974395041031565, "REMICADE": 3.647488837559584, "RINVOQ": 1.7614305854470815, "RITUXIMAB": 1.472592743368764, "SIMPONI": 1.233642667363078, "SKYRIZI": 4.248896072883334, "SOLIRIS": 1.83549649619581, "STELARA": 1.6093980903254697, "SUTENT": 1.0818490840028263, "TACROLIMUS": 6.374138011007898, "TRELEGY": 2.0501469210395187, "TREMFYA": 1.768507250728813, "VENETOCLAX": 5.483313093345237, "VFEND": 8.529956703517415, "VORICONAZOLE": 10.191197263319138, "XELJANZ": 2.864479121445227, "XYREM": 1.9293722740534944, "ZOSTAVAX": 1.290847944331041}
\ No newline at end of file
+{"null": 0.7163233293613893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3302.json
index deff35730d9..604703bd3a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3302.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3302.json
@@ -1 +1 @@
-{"null": 1.5122259400314475}
\ No newline at end of file
+{"null": 0.8452258041202194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3303.json
index ce102ccebbf..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3303.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3303.json
@@ -1 +1 @@
-{"ECULIZUMAB": 1916.125622920623, "null": 2.4949302428072717}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3304.json
index a240fd12675..4595396f500 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3304.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3304.json
@@ -1 +1 @@
-{"RELVAR": 340.40051701151395, "TRELEGY": 86.85027910110327, "null": 1.2457367877776049}
\ No newline at end of file
+{"null": 2.8614231857080017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3305.json
index 8768ed816bd..eb9d4016aa4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3305.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3305.json
@@ -1 +1 @@
-{"CICLOSPORIN": 10.168812572023446}
\ No newline at end of file
+{"ABATACEPT": 2.964061660613872, "ADALIMUMAB": 1.171781766551056, "AFINITOR": 1.0781441883100944, "ARAVA": 1.361509688793632, "BIKTARVY": 4.530478312022907, "BYDUREON": 1.568051823170641, "BYETTA": 2.294999103102726, "CELLCEPT": 1.6733542699023944, "CHAMPIX": 0.8835992764853122, "CIMZIA": 1.765939454774884, "COMBIVIR": 4.001906726626326, "COMIRNATY": 0.618314825892337, "COSENTYX": 2.225189577511625, "CYMBALTA": 0.3909050681485824, "ELIQUIS": 1.3892751373284038, "EMPAGLIFLOZIN": 11.757929021535752, "ENBREL": 2.80734461975285, "FORSTEO": 1.4833459505937363, "GARDASIL": 1.397303424610962, "HUMALOG": 0.6850343954446008, "HUMIRA": 1.5650723978140415, "IBRANCE": 1.615024979395298, "JANUMET": 1.5683928132717249, "JANUVIA": 1.5778505378904362, "KALETRA": 2.8367953289470624, "LANTUS": 0.9695209342523784, "LYRICA": 1.8039723160564844, "MEPOLIZUMAB": 3.0815002917364214, "NEXAVAR": 0.7868617352826464, "OMALIZUMAB": 1.550093770910029, "PEGASYS": 1.406796916478302, "PEGINTRON": 1.2298813693322377, "ROACTEMRA": 2.271671885219236, "SIMPONI": 2.8726562054053923, "SPIKEVAX": 0.3622522664052608, "STELARA": 1.4919712178048623, "SUTENT": 0.8106739580180345, "TOZINAMERAN": 0.7207956083204978, "VAXZEVRIA": 0.208948038266898, "XELJANZ": 4.11087418204537, "XOLAIR": 1.79185248524311, "ZOSTAVAX": 1.357225527167137, "null": 0.9929536164548816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3306.json
index 09507a176f3..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3306.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3306.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 11.052160059673248, "CANCIDAS": 34.02599070962757, "CELLCEPT": 5.553304529585308, "CICLOSPORIN": 3.721347108102508, "HUMIRA": 4.630624753968936, "JARDIANCE": 3.617685638893763, "SUTENT": 2.108026994381724, "ZOSTAVAX": 4.506964963583756}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3307.json
index 051f2d7ab31..8c555a96378 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3307.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3307.json
@@ -1 +1 @@
-{"CICLOSPORIN": 11.222000889169353, "JANUVIA": 17.777012565447045, "null": 1.0043210572211914}
\ No newline at end of file
+{"null": 0.8914085045646701}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3308.json
index 4d17ebfdf82..7c5e061ad78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3308.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3308.json
@@ -1 +1 @@
-{"null": 1.4303389403425195}
\ No newline at end of file
+{"COMIRNATY": 0.4623300014532849, "null": 0.9612028697557742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3309.json
index 4ec0f8bb846..51f1ca4e488 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3309.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3309.json
@@ -1 +1 @@
-{"AUBAGIO": 2.50425359465408, "CELLCEPT": 2.562074973882546, "CICLOSPORIN": 1.4372671893910416, "CIMZIA": 1.6353184046760991, "COSENTYX": 6.551826109813355, "ENTYVIO": 12.67254366788747, "FORSTEO": 1.335610201590089, "FORXIGA": 3.018185129630537, "HUMIRA": 4.98678226308189, "INCIVO": 5.748901220733634, "JARDIANCE": 1.5175761762742428, "NEXAVAR": 2.9628835777323466, "PEGASYS": 2.5750134696979226, "RINVOQ": 5.102242323332209, "ROACTEMRA": 2.4909499354376625, "SIMPONI": 5.276529313312872, "STELARA": 2.379078965461604, "SUTENT": 4.656549656530522, "VOTRIENT": 2.034606580289052, "XELJANZ": 3.8110369997639415}
\ No newline at end of file
+{"null": 0.7591107809894673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/331.json
index c73d343b354..ad4e632672e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/331.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/331.json
@@ -1 +1 @@
-{"AFINITOR": 3.1906543612341203, "DOXORUBICIN": 87.17841772880637, "PEGINTRON": 4.49384184019817, "ROACTEMRA": 6.007747942811758, "null": 1.7016303855584698}
\ No newline at end of file
+{"COMIRNATY": 0.1526056367243637, "JANUMET": 7.760111313751481, "KEYTRUDA": 37.4055659305814, "OPDIVO": 24.177262636318197, "SUTENT": 1.0840115867043616, "YERVOY": 21.74454274747636, "null": 1.0078826979547804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3310.json
index 5de19638c17..29a0de62fe9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3310.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3310.json
@@ -1 +1 @@
-{"ASPARAGINASE": 23.475407961537847, "BUSULFAN": 35.023976255237145, "CASPOFUNGIN": 178.7844656559994, "CICLOSPORIN": 25.438734657666668, "CLOFARABINE": 322.4011120110772, "CYTARABINE": 28.046526531043806, "DEXAMETHASONE": 11.579274969526171, "GANCICLOVIR": 109.73097073532917, "NOXAFIL": 83.96084495144952, "VORICONAZOLE": 70.60356992255576}
\ No newline at end of file
+{"AZTREONAM": 291.21197508291993, "CANNABIDIOL": 92.85989836104471, "CAYSTON": 976.0342656398344, "HUMIRA": 8.13189756307209, "KAFTRIO": 191.5351994941505, "KALYDECO": 602.1557235459907, "ORKAMBI": 856.1778460442332, "SYNAGIS": 10.57188178268562, "TOBI": 706.7825124193597, "TOBRAMYCIN": 77.28903628029178, "XOLAIR": 3.899683002506681, "null": 0.7160029524462073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3311.json
index 99d10a46a37..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3311.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3311.json
@@ -1 +1 @@
-{"OPTIMARK": 3836.558883516212}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3312.json
index 3a5bdbfc17d..4b9cbdbda13 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3312.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3312.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0744947267450562}
\ No newline at end of file
+{"ORKAMBI": 1762.147212870255}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3313.json
index 77c917b1f94..c7bbe0dda16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3313.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3313.json
@@ -1 +1 @@
-{"ABILIFY": 1.0110607165708825, "ACE": 4.17521670958171, "ACLASTA": 2.719988534161316, "ADEMPAS": 1.1164443609139243, "AERIUS": 1.0921725804187377, "ALL": 1.2500881015641758, "AMBRISENTAN": 1.1968491636335656, "APIXABAN": 1.6029898943100482, "APREMILAST": 4.878979213777744, "ARAVA": 1.986248440148795, "ATEZOLIZUMAB": 1.2907968775073173, "ATRIPLA": 1.081649169245225, "AUBAGIO": 5.305405366597203, "AVONEX": 3.953901283039694, "AZILECT": 5.82534501337816, "AZOPT": 1.408036105554508, "BELIMUMAB": 2.3867051105033426, "BENLYSTA": 1.0683316968011936, "BETAFERON": 3.1365146214785318, "BEXSERO": 1.2869456246371136, "BEXTRA": 3.784012884400332, "BRIVARACETAM": 2.176449379460503, "BRIVIACT": 1.4001959003282507, "CABAZITAXEL": 1.1847013098957886, "CABOTEGRAVIR": 1.571918066708733, "CARBIDOPA": 5.465816621303948, "CELECOXIB": 1.4175486175930614, "CERTOLIZUMAB": 3.986380168896669, "CHEMOTHERAPY": 3.641648044473112, "COAPROVEL": 1.075963538172831, "COMTAN": 4.0188187696866455, "COMTESS": 2.5835720337228936, "CONTRAST": 1.9260001480967412, "COSENTYX": 1.5576231325073284, "CYMBALTA": 1.3647639793112485, "DOLUTEGRAVIR": 1.2026498914424693, "DOVATO": 2.645975776467828, "DULAGLUTIDE": 1.7396048612853388, "DULOXETINE": 1.7694478849994293, "DUPIXENT": 1.2210915867355745, "EBIXA": 4.342091129024138, "ENALAPRIL": 4.454981946324356, "ENBREL": 1.8245210698061904, "ENTACAPONE": 5.715473017294619, "ENTRESTO": 1.175719680144062, "EPIDYOLEX": 3.542660249876295, "ERELZI": 2.1276865835148926, "ERENUMAB": 1.302689307960537, "EVISTA": 1.451752502701653, "EXELON": 1.0571930162291467, "EXFORGE": 1.4912831804753612, "FAMPRIDINE": 14.216737476896416, "FAMPYRA": 15.309001813817172, "FASENRA": 1.3284709900045468, "FASLODEX": 2.2563659897000767, "FIRDAPSE": 4.109778868059983, "FORSTEO": 2.968184617740329, "FYCOMPA": 5.531031494229634, "GALVUS": 1.0823344645214052, "GARDASIL": 1.8888198463693056, "GILENYA": 3.163418741868322, "HEPSERA": 3.527330392331271, "HUMALOG": 1.7373972659723325, "HUMIRA": 1.5839865691626782, "HYDROCORTISONE": 1.130665145396625, "IBRANCE": 1.5199534902761755, "IBUPROFEN": 1.0498924391493645, "IMBRUVICA": 1.10167177776017, "INLYTA": 1.6249826906864249, "INSULIN": 1.1310287329758997, "INTELENCE": 3.419045602104735, "IRON": 1.1852200586990516, "KEPPRA": 1.6149947155652102, "KESIMPTA": 3.7844230336159583, "LACOSAMIDE": 1.9063208007038892, "LANTUS": 1.532938868489674, "LATUDA": 1.0657202600524325, "LEFLUNOMIDE": 1.5203441230107295, "LEMTRADA": 2.2492963836956643, "LEVETIRACETAM": 1.1683447811206844, "LEVODOPA": 3.2517731590100625, "LEVOFLOXACIN": 1.478441884192781, "LYRICA": 2.994555795534975, "MAVENCLAD": 1.145603726387752, "MEMANTINE": 3.2962636372886243, "MIMPARA": 1.0220394387565013, "MIRABEGRON": 1.5852875818372465, "MMRVAXPRO": 1.2915989683411442, "MULTAQ": 1.379810462149272, "NAGLAZYME": 1.2025590047292174, "OCRELIZUMAB": 3.157758411947072, "OCREVUS": 3.4849616183587555, "OLANZAPINE": 1.2762022904477637, "OPTIMARK": 2.923623985302247, "ORENCIA": 3.204433564804455, "OXYBUTYNIN": 1.6443856081929435, "PANTOPRAZOLE": 1.0416878401511824, "PERAMPANEL": 3.9467880703460914, "PLEGRIDY": 2.076914138201289, "PREGABALIN": 1.7216037786917526, "PROLIA": 1.0931332548548311, "RANEXA": 1.6703272439594965, "RANOLAZINE": 1.9401031309441688, "REBIF": 3.56838493303375, "REKAMBYS": 3.320230228748158, "REVATIO": 1.448595188031452, "RISPERIDONE": 1.871935755735179, "RUBRACA": 1.3168534239565104, "SEEBRI": 2.6081291657201287, "SHINGRIX": 1.0470611133951082, "SIFROL": 2.173291515652892, "SOMAVERT": 3.1426323205125577, "SPIRONOLACTONE": 1.2174856913834882, "STALEVO": 3.877159360383796, "STIVARGA": 1.2458738545230472, "STRIBILD": 1.114737948609323, "SUTENT": 1.8578154956340325, "SYCREST": 1.6823211446452937, "SYNFLORIX": 2.308275650073966, "TAMIFLU": 1.018916184557341, "TASIGNA": 1.0110423643995083, "TECFIDERA": 3.117955456330314, "TELMISARTAN": 1.4446946204312487, "TERIFLUNOMIDE": 3.353421973267857, "TERIPARATIDE": 1.106972346984894, "TOUJEO": 1.1377663140342609, "TOVIAZ": 2.5453545002188736, "TOZINAMERAN": 1.351210003508257, "TRUVADA": 1.008224304934459, "TWINRIX": 1.422445306560121, "TYSABRI": 2.957715467588762, "UNKNOWN": 1.4842018580991407, "UNSPECIFIED": 1.3148823001171397, "VIMPAT": 2.31077461611732, "XELJANZ": 2.9117528723951662, "XTANDI": 2.0612346267840835, "ZAVESCA": 2.393718534160985, "ZEJULA": 1.949386579531324, "ZINBRYTA": 1.6226937794328886, "ZYPADHERA": 4.805018332407942, "ZYPREXA": 1.1565177184097843, "null": 1.1804865590295626}
\ No newline at end of file
+{"null": 1.2052203392349996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3314.json
index 38eef05333d..50607d5106c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3314.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3314.json
@@ -1 +1 @@
-{"ABATACEPT": 5.8667863394743, "ADALIMUMAB": 4.023355525729077, "APREMILAST": 7.760141213654442, "APREPITANT": 1.7680620887107457, "ARAVA": 2.2396155511784417, "AUBAGIO": 2.939628766244774, "BENLYSTA": 1.232806335497268, "BETAFERON": 2.088595588605608, "BEXSERO": 2.21949700602106, "BUMETANIDE": 5.126562271467251, "BUPIVACAINE": 3.013128516961692, "CIMZIA": 1.037296917489663, "COMTAN": 3.5663399119569354, "CONTRAST": 3.691080789939184, "COSENTYX": 1.3571313400202618, "CYMBALTA": 1.0524531123761889, "DULAGLUTIDE": 2.255597690945153, "DULOXETINE": 1.700648009254894, "ENBREL": 3.1174733891132624, "ETANERCEPT": 6.314367742740171, "EVENITY": 1.1850155982274493, "FAMPRIDINE": 5.978552544820518, "FAMPYRA": 11.167613368151832, "FIRDAPSE": 3.0748778697231858, "FORSTEO": 1.761479113533215, "FULVESTRANT": 1.4751884019621375, "GALVUS": 2.101608930772624, "GARDASIL": 2.527331687040578, "HEPSERA": 1.61685396748361, "HIZENTRA": 1.02945226140639, "HUMALOG": 2.161026674735167, "HUMIRA": 1.334688989605313, "IBRANCE": 2.2766574761895844, "INCRUSE": 1.112353912760455, "INFANRIX": 1.046956701034688, "INLYTA": 2.51551395858585, "KESIMPTA": 1.308452932925344, "LANTUS": 1.5185129936858424, "LATUDA": 1.4118137271642892, "LEVOFLOXACIN": 1.4016764347345532, "LYRICA": 2.677998695615264, "MELATONIN": 1.5745371351285555, "MEPOLIZUMAB": 2.3049845961166917, "METHOTREXATE": 1.0327607780894346, "MIMPARA": 3.216013705819196, "MYCOPHENOLATE": 1.0929834890810737, "NAGLAZYME": 1.8341290295205173, "NEXAVAR": 1.7108003304863366, "OCRELIZUMAB": 3.200188349749077, "OPTIMARK": 4.764938781471843, "PLAVIX": 1.1596443600087178, "PREVENAR": 1.534826368651198, "RINVOQ": 1.4260252096699766, "SHINGRIX": 1.594240554007807, "SIMPONI": 1.0236069570241084, "SPINRAZA": 6.485456111872511, "STALEVO": 3.887561247038376, "STIVARGA": 1.1464669923362991, "SUTENT": 2.52343875919667, "TOUJEO": 1.6900102636922618, "TOZINAMERAN": 1.7794700741960847, "VALSARTAN": 1.715300275003923, "VIMPAT": 1.1992759822415124, "XALKORI": 1.0304345354862077, "XELJANZ": 4.452290267539713, "XTANDI": 2.4856700675003744, "null": 1.0290872165526197}
\ No newline at end of file
+{"KALYDECO": 1163.827272484795, "ORKAMBI": 4273.055114918833, "null": 0.2190277761409841}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3315.json
index f7111adc516..047e31d7e7a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3315.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3315.json
@@ -1 +1 @@
-{"IRBESARTAN": 545.6683246105284}
\ No newline at end of file
+{"BEDAQUILINE": 144.7026977687118, "null": 0.4927658567036258}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3316.json
index 7424f850cd2..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3316.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3316.json
@@ -1 +1 @@
-{"ABILIFY": 7.464655617758531, "AIMOVIG": 3.7777804707738607, "ARIPIPRAZOLE": 4.747142421447222, "BRINTELLIX": 4.601627345912456, "CYMBALTA": 1.5925247747367812, "INVEGA": 68.16745256660197, "LATUDA": 11.607195555130296, "OLANZAPINE": 8.440105828096973, "RISPERIDONE": 10.581923308275991, "ZYPREXA": 18.076007985334044, "null": 4.228099880272463}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3317.json
index d0f25025ba7..d1d520143a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3317.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3317.json
@@ -1 +1 @@
-{"COMIRNATY": 6.216119076216367, "SPIKEVAX": 1.5978551298647674}
\ No newline at end of file
+{"ABATACEPT": 0.2289090330868201, "ADALIMUMAB": 0.071525783268698, "AFINITOR": 1.33324947950188, "AIMOVIG": 0.2825254485464925, "ALIMTA": 0.7795532025046154, "ALISKIREN": 45.12453802384778, "ARAVA": 0.306364344269968, "ASPARAGINASE": 7.2690700648376225, "AUBAGIO": 2.993392101727143, "AVASTIN": 0.8619549230843604, "AYESURBY": 286.7213948366054, "BELIMUMAB": 5.0608465792277615, "BENLYSTA": 2.3083500739572926, "BETMIGA": 9.102223441629466, "BEVACIZUMAB": 0.7663957025848337, "BUDESONIDE": 0.283002569140309, "BUSULFAN": 0.7662148931888845, "BYDUREON": 0.6367229405319239, "BYETTA": 1.6150300237774666, "CELECOXIB": 5.055485003510575, "CELLCEPT": 1.0841363167060083, "CHAMPIX": 0.201698500422629, "CICLOSPORIN": 0.5575627026184037, "CIMZIA": 1.8913992998064424, "CLOPIDOGREL": 5.4952060275836025, "COMIRNATY": 0.4273749895549075, "COSENTYX": 1.759825989571919, "CYMBALTA": 0.8553983392572178, "DEXAMETHASONE": 0.5463095071284998, "DULOXETINE": 3.402491837883087, "ELIQUIS": 1.0434213596806283, "EMPAGLIFLOZIN": 7.275308835706903, "ENBREL": 0.6614490040038129, "ENTRESTO": 0.3069263372233646, "ENTYVIO": 1.248691198256161, "ESBRIET": 3.118060009756329, "EVISTA": 1.537946925639445, "EXJADE": 1.676191476634105, "FAMPYRA": 17.69065796135246, "FASENRA": 1.5682875604023028, "FASLODEX": 1.1222841505291636, "FIRDAPSE": 1.6389775080414666, "FORSTEO": 1.877834032513315, "FORXIGA": 8.854479253093299, "GARDASIL": 1.4747636899579866, "HERCEPTIN": 1.2391353459166103, "HIZENTRA": 2.3998653903890856, "HUMALOG": 1.5428109567934398, "HUMIRA": 5.968884211479018, "IBRANCE": 2.1645833552915485, "INLYTA": 0.9275484251462522, "IRESSA": 1.7037729050464203, "JAKAVI": 1.5569658019897836, "JANUMET": 1.0208674524862436, "JANUVIA": 0.8647163583140239, "JARDIANCE": 10.21087668267749, "KEPPRA": 0.4650115112129262, "KEYTRUDA": 0.913202703176835, "LANTUS": 1.0532280271537189, "LEMTRADA": 1.6042415934532146, "LEVEMIR": 0.703906585407209, "LEVOFLOXACIN": 0.6316951604525177, "LYRICA": 1.7363230493584696, "MEPOLIZUMAB": 0.697964586917475, "METHOTREXATE": 2.01726422825232, "MICARDIS": 3.167948942080643, "NEXAVAR": 0.3509998525243885, "NUCALA": 7.114349586636779, "OCRELIZUMAB": 1.461004805258136, "OMALIZUMAB": 1.8216927719771303, "OPDIVO": 0.6766844660677351, "OPSUMIT": 1.0925686040048417, "ORENCIA": 7.157876606904978, "OXYBUTYNIN": 4.537729432017505, "PEGASYS": 1.3514406178091125, "PEGINTRON": 1.0562022049507451, "PLAVIX": 0.3119507320710697, "PLEGRIDY": 1.6098708676815034, "REMICADE": 2.0708954514278317, "REVATIO": 1.8408514019153808, "RINVOQ": 0.8609832864992167, "RITUXIMAB": 1.6263075981310235, "ROACTEMRA": 2.347885195989741, "SAXENDA": 1.022190527644241, "SIMPONI": 2.1291264810773787, "SOLIRIS": 0.8366173333970234, "SPIKEVAX": 0.312538630016339, "SPRYCEL": 0.7700519244393521, "STELARA": 1.136345630027619, "SUBOXONE": 0.6196652227649617, "SUTENT": 0.6417596953616037, "TASIGNA": 0.5055775454903713, "TOVIAZ": 11.190037512622222, "TOZINAMERAN": 0.4995991109994162, "TRACLEER": 1.477270468697178, "TRELEGY": 1.5287106891759124, "TREMFYA": 2.2067979359127023, "TRULICITY": 0.7308211416901107, "VAXZEVRIA": 0.2486257815781025, "VELTASSA": 1.6979295474519167, "VOTRIENT": 0.3739722693280397, "XELJANZ": 6.145813706487544, "XOLAIR": 0.5887386900879319, "XTANDI": 2.7696308003593666, "ZOSTAVAX": 1.0073544883793328, "ZYPREXA": 0.3729947164472877, "null": 0.8836707634367197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3318.json
index 48bfe588523..868d712e063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3318.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3318.json
@@ -1 +1 @@
-{"null": 4.191688272364003}
\ No newline at end of file
+{"ASPARAGINASE": 710.7920020275193, "null": 0.1262229707550563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3319.json
index ce46f5b692c..5fd11f18157 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3319.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3319.json
@@ -1 +1 @@
-{"AFINITOR": 2.0746916290197914, "ARAVA": 1.075447507861581, "AUBAGIO": 1.8176138720982289, "BYDUREON": 7.263886961634887, "BYETTA": 8.018638933051415, "CIMZIA": 1.4414338249472527, "CYMBALTA": 1.0019232903025432, "ELIQUIS": 3.4842369177734325, "ENBREL": 1.4271453297373993, "ENTYVIO": 1.4460112510411631, "EXFORGE": 1.8071673862453543, "EXJADE": 1.6846798078387946, "GARDASIL": 1.191523874187682, "HUMALOG": 1.881773350375139, "IBRANCE": 1.6708143741501391, "INLYTA": 2.248766413252454, "JAKAVI": 1.5336814838844144, "JANUMET": 6.891627969314778, "JANUVIA": 6.886045928748315, "LANTUS": 3.966837792041651, "OPSUMIT": 2.1534850725685084, "PEGINTRON": 1.871994105302664, "REVATIO": 7.465311595919974, "SAXENDA": 8.285145149548281, "SIMPONI": 1.2927467873120726, "SOLIRIS": 2.304502041323132, "SPRYCEL": 2.766935122549561, "SUBOXONE": 6.179491686137548, "SUTENT": 2.166864749064883, "TRULICITY": 2.369736299881586, "VFEND": 3.3904163348875427, "VIAGRA": 2.3174803065703093, "VICTOZA": 7.830432206339846, "XELJANZ": 2.833626593982784, "ZOSTAVAX": 1.809558059858458, "null": 1.5119398355322864}
\ No newline at end of file
+{"null": 0.5506697885075955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/332.json
index 3a042f9289d..1778fd0146f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/332.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/332.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 15.19109012098996, "ELIQUIS": 1.8563243653194008, "EYLEA": 24.41685404279485, "TICAGRELOR": 39.52333191306073, "null": 1.0774639327985227}
\ No newline at end of file
+{"null": 1.7596661781553844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3320.json
index 94baad9cd1e..ff22a194a0a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3320.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3320.json
@@ -1 +1 @@
-{"CYTARABINE": 11.8698628159706, "JANUMET": 9.24346013856321, "JANUVIA": 9.142924728060771, "KEYTRUDA": 2.3227715616830014}
\ No newline at end of file
+{"ALEMTUZUMAB": 9.526304037272157, "ASPARAGINASE": 6.655472784189851, "BASILIXIMAB": 21.471801644819102, "BORTEZOMIB": 6.279403976036073, "BRILIQUE": 4.105835341271633, "BUDESONIDE": 4.280759508910763, "BUSILVEX": 97.63855129890494, "BUSULFAN": 217.36388127118727, "CARMUSTINE": 15.226128801722451, "CELLCEPT": 8.64488505707026, "CICLOSPORIN": 22.79806941984183, "CLOPIDOGREL": 0.8607622073349761, "COMIRNATY": 0.0918719477972407, "CYTARABINE": 8.201168753931636, "DEFITELIO": 116.9428865386252, "DEXAMETHASONE": 2.571025902191264, "ELIQUIS": 1.375213221817137, "FORXIGA": 5.607149586070795, "HALAVEN": 7.96119926418608, "IRESSA": 24.063605984710385, "JAKAVI": 2.962347958511822, "JARDIANCE": 2.4965231784904693, "JEVTANA": 10.950967666655863, "KEYTRUDA": 0.809138776899129, "MELPHALAN": 19.226264651319976, "METHOTREXATE": 2.8774023864430025, "MYCOPHENOLATE": 9.580642855830051, "RITUXIMAB": 2.4250616369948124, "THIOTEPA": 41.35647694111013, "VAXZEVRIA": 0.0449912993450958, "VFEND": 2.06393136575977, "null": 0.7460044047713206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3321.json
index 80626b5cf87..069666352fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3321.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3321.json
@@ -1 +1 @@
-{"null": 1.2834699380452856}
\ No newline at end of file
+{"COMIRNATY": 0.3543398592687565, "GARDASIL": 3.785367848051517, "INSULIN": 35.49558046118092, "VAXZEVRIA": 0.2997966539990803, "null": 0.9093826186697336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3322.json
index 980f60bd0c5..57a24b12268 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3322.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3322.json
@@ -1 +1 @@
-{"null": 1.4013036081895904}
\ No newline at end of file
+{"null": 0.5253215492245955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3323.json
index 765d3fafb58..c20cbc12a62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3323.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3323.json
@@ -1 +1 @@
-{"BYETTA": 5.221135924767798, "CIMZIA": 2.899607146638193, "ELIQUIS": 1.408114400156858, "FORSTEO": 3.3746376991599685, "IBRANCE": 4.232354761415636, "JANUMET": 6.848911325784205, "JANUVIA": 7.394897326739481, "LANTUS": 5.667574326000998, "SAXENDA": 17.142103989999185, "SIMPONI": 12.637379452889215, "STELARA": 3.60637943280836, "ZOSTAVAX": 4.415855434840808, "null": 1.4687165208854336}
\ No newline at end of file
+{"COMIRNATY": 3.8184021863473143, "COSENTYX": 2.50872558308746, "FAMPYRA": 29.167895965837065, "JARDIANCE": 4.859477736873752, "KESIMPTA": 32.19185824680456, "KEYTRUDA": 1.31069174490902, "SPIKEVAX": 1.6340394818629929, "VAXZEVRIA": 0.6006761345303394, "null": 0.3262221925015388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3324.json
index 5445af55ec1..e2a2f64e786 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3324.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3324.json
@@ -1 +1 @@
-{"PEGASYS": 3.80025163421434, "null": 1.5140940013364976}
\ No newline at end of file
+{"IRESSA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3325.json
index 8b518bfd089..bac674c2fa1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3325.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3325.json
@@ -1 +1 @@
-{"SIFROL": 231.20483300422177, "null": 2.2942244644057808}
\ No newline at end of file
+{"null": 1.2435810430680123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3326.json
index 47492116daf..0d1db275d19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3326.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3326.json
@@ -1 +1 @@
-{"ABILIFY": 26.91008209519553, "ARIPIPRAZOLE": 9.532978621218872, "AZILECT": 148.12390542308947, "CARBIDOPA": 56.06616473204656, "ENTACAPONE": 151.69592192483438, "LEVODOPA": 254.79365735789688, "SIFROL": 821.3678350455043, "STALEVO": 38.28915995569985, "null": 1.94425338201139}
\ No newline at end of file
+{"ALEMTUZUMAB": 76.63998042800083, "BUSULFAN": 114.93256842262576, "CELLCEPT": 30.449039427165506, "CICLOSPORIN": 20.77143713824957, "null": 0.1877658041584562}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3327.json
index 59f2f112269..21f8e554eee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3327.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3327.json
@@ -1 +1 @@
-{"ADCIRCA": 212.78407609137832, "null": 1.3248143229064302}
\ No newline at end of file
+{"null": 1.0377807121730769}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3328.json
index bd8aa874d66..d202a0a9dac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3328.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3328.json
@@ -1 +1 @@
-{"ELIQUIS": 3.933919987423834, "KEYTRUDA": 4.863213612616732, "OBETICHOLIC": 1002.8322798423314, "OCALIVA": 239.1050901814988}
\ No newline at end of file
+{"ACLASTA": 208.705853387233, "FORSTEO": 9.60153123624882, "ZOSTAVAX": 12.481668339773291, "null": 1.708120044782933}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3329.json
index 582033b5638..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3329.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3329.json
@@ -1 +1 @@
-{"ABACAVIR": 1.6649907278158111, "ACTOS": 4.159142762667941, "ADENURIC": 2.2324113750861883, "AFINITOR": 1.314477737440857, "ALIMTA": 1.7072224248051522, "AMIKACIN": 3.0065535079785235, "AMINOSALICYLIC": 1.4614779165566791, "ANAKINRA": 1.4491699821086763, "APROVEL": 3.5165481676759587, "ARIXTRA": 3.6155011095293967, "ASPARAGINASE": 1.145682032842511, "AUBAGIO": 3.847512088108151, "AVANDIA": 1.0994501664983896, "AZATHIOPRINE": 1.22054571508159, "BARACLUDE": 4.92038040648754, "BEDAQUILINE": 1.1826034318127208, "BETAFERON": 8.029269148548016, "BONVIVA": 1.0611815454456086, "BRAFTOVI": 1.3640768468879352, "BUSILVEX": 3.423438738546759, "CAELYX": 1.5715457020425676, "CANCIDAS": 9.246756972660862, "CASPOFUNGIN": 2.0420539005657545, "CELLCEPT": 1.4805935212216463, "CELSENTRI": 5.677064344594642, "COBIMETINIB": 3.527311734242254, "COMBIVIR": 1.6218416852792965, "COMPLEMENT": 16.21460878059043, "COMTAN": 2.878456788201641, "COSENTYX": 1.0922997060594215, "COTELLIC": 2.860585250027473, "CRESEMBA": 5.037255494651044, "CRIXIVAN": 3.876819013571757, "CYMBALTA": 1.4442773671031517, "CYTARABINE": 1.1538854208021465, "DACLATASVIR": 4.354495610237676, "DASATINIB": 3.001164960339424, "DELAMANID": 9.24921827736326, "DENOSUMAB": 2.874228615359094, "EBIXA": 3.5665522441535016, "EFAVIRENZ": 1.605070204223319, "ELIQUIS": 1.743004233918229, "EMTRICITABINE": 1.5326885518801514, "ENTRESTO": 1.2166543978896127, "EPIVIR": 6.249540266558678, "ERLEADA": 1.073384297575979, "ESBRIET": 1.6311565217160149, "ESMYA": 14.908905864081284, "ESOMEPRAZOLE": 2.4268568895820968, "EUCREAS": 8.70891737749009, "EXFORGE": 1.2270065586725976, "EXJADE": 1.6466109305413197, "FULVESTRANT": 1.2174343771761291, "GALVUS": 8.293864592374037, "GAZYVARO": 1.9556767284942853, "GILENYA": 5.714944132661755, "GLIVEC": 2.202234744166533, "HALAVEN": 1.2272842509480208, "HEPSERA": 1.767094278908219, "ICLUSIG": 1.7047702188254057, "INSULATARD": 5.082973939784116, "INVIRASE": 3.3824270447191336, "IRBESARTAN": 1.6252457728320058, "ISENTRESS": 1.2138028733553754, "JAKAVI": 2.019812523132024, "JANUMET": 1.4921002808071568, "JANUVIA": 1.140787135030928, "JEVTANA": 1.0934963726492364, "KAFTRIO": 4.973081904227797, "KALETRA": 2.515223167328671, "KEPPRA": 2.1879518590832103, "KESIMPTA": 1.5708990422585842, "KISQALI": 4.02842079859986, "KIVEXA": 4.525833059178416, "LAMIVUDINE": 2.071123211880536, "LEMTRADA": 1.8970550939265776, "LEVOFLOXACIN": 1.1107785505314558, "LIXIANA": 4.238830062019366, "LYSODREN": 12.242512024210331, "MANNITOL": 5.852570473464167, "MAVENCLAD": 4.950399284891678, "MEKINIST": 1.7047008091592848, "MICARDIS": 2.3476808176981048, "MIMPARA": 1.3332901566010942, "MULTAQ": 13.096070626026156, "NEXAVAR": 1.6878130422257671, "NORVIR": 1.7311625214887991, "NOVONORM": 3.979566684953581, "NOXAFIL": 5.3613844045880565, "OCALIVA": 6.577725107121158, "OFEV": 4.293371678104928, "OLANZAPINE": 1.9974629336612264, "ORKAMBI": 1.6392008882508833, "PANTOPRAZOLE": 1.5530967150178576, "PEGASYS": 1.1865074374006297, "PEGINTERFERON": 1.6938935292548585, "PLAVIX": 1.4064759360617347, "PLEGRIDY": 2.387394514153906, "PRADAXA": 1.4442169866067611, "PROTELOS": 5.077490286593045, "RASILEZ": 3.882335517987928, "REYATAZ": 2.030095205158305, "RIBOCICLIB": 3.1493419256252144, "RINVOQ": 1.504054216247897, "ROACTEMRA": 2.729119837730104, "STIVARGA": 1.2045503567577525, "STOCRIN": 13.98440149259873, "SUSTIVA": 14.588066774648752, "TASIGNA": 2.2082758285107484, "TEMODAL": 3.190926144679189, "TRACLEER": 8.540162960316653, "TREMFYA": 2.576962333714977, "TRULICITY": 1.0031734025374022, "TWINRIX": 3.58346641813296, "VALDOXAN": 10.651416251477333, "VEKLURY": 5.193114548116566, "VENCLYXTO": 1.5998372816400326, "VFEND": 13.004802692565416, "VIRAMUNE": 8.272662946028708, "VORICONAZOLE": 4.5742565337314405, "VOTRIENT": 1.9677678015157976, "XALKORI": 1.2752268661823356, "XARELTO": 1.1753781245328496, "YONDELIS": 6.669493541020436, "ZELBORAF": 2.8100449585369094, "ZINBRYTA": 6.332316417040714, "ZYPREXA": 4.241921089613284, "null": 2.222497590153365}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/333.json
index 77ec9d4c9f4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/333.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/333.json
@@ -1 +1 @@
-{"ADALIMUMAB": 11.048218284906964, "COMIRNATY": 1.1778094819345408, "EYLEA": 45.614817599800816}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3330.json
index 587d537f805..24c6f3846c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3330.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3330.json
@@ -1 +1 @@
-{"ALISKIREN": 201.6938769709754, "ELIQUIS": 1.6756353970925182, "FORXIGA": 6.784016523611853, "HUMALOG": 9.007006637029564, "INSULIN": 6.018093249937285, "INVOKANA": 117.15922691018568, "JANUMET": 1.8090289189347504, "JARDIANCE": 17.595760484441676, "LANTUS": 5.498591432136584, "LEVEMIR": 5.532445247267643, "MIXTARD": 31.619309296179427, "NEXAVAR": 1.0278529861575196, "OPTIMARK": 3.024234135694025, "PLAVIX": 1.1768786388978465, "ROACTEMRA": 2.341501140583239, "SIMPONI": 1.3745471375537783, "SUTENT": 1.178908258097746, "TASIGNA": 13.01727473089618, "TRACLEER": 3.409082278858314, "null": 1.113903463000993}
\ No newline at end of file
+{"APIDRA": 18.278451591534186, "BRAFTOVI": 27.702178957664, "COMIRNATY": 0.1709741518049, "EYLEA": 22.43938705838714, "NEPAFENAC": 1901.787519708332, "NEVANAC": 301.8571052958036, "SPIKEVAX": 0.3085412063617474, "VAXZEVRIA": 0.1878770357995994, "null": 0.7387451259109641}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3331.json
index d59da7cf449..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3331.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3331.json
@@ -1 +1 @@
-{"INVOKANA": 273.96623485230424, "null": 1.158629917492077}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3332.json
index 949bbae2866..bd92c475cce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3332.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3332.json
@@ -1 +1 @@
-{"COSENTYX": 22.427734851461462, "null": 1.249525771719718}
\ No newline at end of file
+{"CYTARABINE": 16.441332592410845, "null": 2.418813572768727}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3333.json
index f8ca8de5b12..9541af21aa2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3333.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3333.json
@@ -1 +1 @@
-{"ELIQUIS": 5.442689839722771, "NEXAVAR": 30.554153342376058, "TOZINAMERAN": 1.876593764024024}
\ No newline at end of file
+{"ABRAXANE": 137.05939990758466, "BOSULIF": 61.93299498831032, "BOSUTINIB": 558.0943125641259, "CYTARABINE": 7.301649011767729, "DASATINIB": 936.66730643815, "GLIVEC": 121.67699341122147, "ICLUSIG": 19.693262216928247, "IMATINIB": 549.742567501261, "NILOTINIB": 695.3249029532374, "TASIGNA": 104.50752791423832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3334.json
index 25ee795a0cf..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3334.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3334.json
@@ -1 +1 @@
-{"BYETTA": 10.311398945272376, "CYMBALTA": 16.538125688367607, "LATUDA": 30.53803614419454, "null": 1.062057967082555}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3335.json
index 47363562476..ddf3667cf09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3335.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3335.json
@@ -1 +1 @@
-{"CARMUSTINE": 7.934386489609373, "CELLCEPT": 1.0945314712480538, "CICLOSPORIN": 1.0182243028944644, "ELIQUIS": 1.7033771968212594, "JANUVIA": 1.0526248520045076, "RINVOQ": 1.095184433430156, "SIMPONI": 1.5684284992442503, "STELARA": 2.1008916435810434, "TREMFYA": 2.30277336883202, "TRULICITY": 1.3951786282061651, "null": 8.347281463402279}
\ No newline at end of file
+{"TESTOSTERONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3336.json
index a9dfc746e97..9124accaeb4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3336.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3336.json
@@ -1 +1 @@
-{"null": 2.329282992563667}
\ No newline at end of file
+{"ANAKINRA": 4.416757915303097, "ASPARAGINASE": 1.036421999531392, "ATEZOLIZUMAB": 6.161973818140658, "AXICABTAGENE": 532.035408602709, "BLINATUMOMAB": 60.497231790518974, "BLINCYTO": 70.70118927729445, "BORTEZOMIB": 3.2098951539082066, "BREYANZI": 794.6843891100432, "BUSULFAN": 2.2445921425675026, "CARFILZOMIB": 6.1128388062867485, "COMIRNATY": 0.0074843066957519, "COTELLIC": 2.0423892588583823, "CYTARABINE": 4.605035216977831, "DARZALEX": 2.1422815053123103, "DESCOVY": 5.034159612622109, "DEXAMETHASONE": 3.647737899475375, "DOXORUBICIN": 5.501413541788695, "EPCORITAMAB": 379.7417768100353, "GAZYVARO": 7.439178634620165, "GLOFITAMAB": 625.5810417020712, "IPILIMUMAB": 2.778727039835094, "JAKAVI": 0.548312838522311, "KEYTRUDA": 2.5720050915571866, "KYMRIAH": 586.2176351714313, "LEMTRADA": 0.928018401015282, "LENALIDOMIDE": 7.951307032179892, "LISOCABTAGENE": 608.0119262676772, "MEKINIST": 1.8300029393878183, "NIVOLUMAB": 9.828316228198046, "OBINUTUZUMAB": 4.613834293176742, "OPDIVO": 11.937667423042948, "PEMBROLIZUMAB": 3.1609458975146016, "QARZIBA": 12.1959651985146, "RITUXIMAB": 3.11949070750866, "RIXATHON": 5.886648882569596, "TISAGENLECLEUCEL": 372.884739585333, "TOCILIZUMAB": 4.830400873570399, "YESCARTA": 1132.215433833366, "null": 0.1453663038697299}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3337.json
index 7fedae4c111..353a1a08438 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3337.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3337.json
@@ -1 +1 @@
-{"FENTANYL": 38.80431604176108, "LEVEMIR": 13.06417487450303, "null": 1.1699766831529703}
\ No newline at end of file
+{"APREMILAST": 66.60349547674689, "AXICABTAGENE": 207.16301814372397, "BUDESONIDE": 5.147149514008574, "COMIRNATY": 0.250804452025975, "JAKAVI": 25.902007661000315, "KEYTRUDA": 13.275480015917, "KYMRIAH": 35.87193091251117, "SPIKEVAX": 0.4629074666534432, "TOZINAMERAN": 1.7594907733357086, "VAXZEVRIA": 0.1603533575656114, "YESCARTA": 113.96681113744314, "null": 0.3994901765592462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3338.json
index aafa73f8436..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3338.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3338.json
@@ -1 +1 @@
-{"RILUTEK": 847.6445785237527, "null": 1.0047605513897269}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3339.json
index e405e92f96a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3339.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3339.json
@@ -1 +1 @@
-{"AFINITOR": 1.2478296628790635, "ALIMTA": 1.3200400513240922, "APIDRA": 1.3413171087693303, "ARANESP": 1.791766277676787, "AVASTIN": 2.5488917458702662, "BONVIVA": 4.123335901182265, "BRILIQUE": 29.407278115328136, "CLOPIDOGREL": 14.538314558803004, "CYTARABINE": 1.288902264814017, "DEFITELIO": 17.818560609472588, "EFIENT": 28.402176758269, "ELIQUIS": 11.68614236482202, "ENOXAPARIN": 3.04311381337581, "ETANERCEPT": 14.295689138236703, "EVEROLIMUS": 5.885428147723778, "EXJADE": 1.6771342191547391, "HEMLIBRA": 13.331516630039411, "I": 389.9155962150428, "IBUPROFEN": 1.6555323082197415, "ISCOVER": 21.5939574161558, "JAKAVI": 1.4136761007277252, "JANUMET": 1.5682244046487008, "LENVIMA": 2.6897151412464675, "LIXIANA": 15.098828263106984, "MIMPARA": 5.117987947110145, "NEXAVAR": 5.518878763099375, "OFEV": 2.6180614604235624, "OPSUMIT": 1.757899530477084, "PANTOPRAZOLE": 2.038616831747365, "PLAVIX": 22.330132128091737, "SPRYCEL": 1.652873466688148, "SUTENT": 5.343155196045708, "TICAGRELOR": 9.73669946209261, "VOTRIENT": 2.406679903127493, "XARELTO": 3.496552743041361, "null": 1.1880254865999822}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/334.json
index f29c39619bf..db9fc391e70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/334.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/334.json
@@ -1 +1 @@
-{"null": 2.44932772245501}
\ No newline at end of file
+{"null": 0.998193471464212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3340.json
index b6807e4ce15..e54cc0f4e60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3340.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3340.json
@@ -1 +1 @@
-{"null": 1.0414549261435924}
\ No newline at end of file
+{"ARAVA": 9.794531187846172, "null": 0.4546645556637538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3341.json
index 40e2723ed55..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3341.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3341.json
@@ -1 +1 @@
-{"CIMZIA": 3.1284584018076647, "HIZENTRA": 13.862621940632469, "IBRANCE": 3.961239749304833, "SIMPONI": 4.3585492620818185, "SUTENT": 1.5740437130428118, "XELJANZ": 8.39149014995089, "null": 1.0552827740444353}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3342.json
index d78e65732c8..94c900ef385 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3342.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3342.json
@@ -1 +1 @@
-{"null": 4.688159595029086}
\ No newline at end of file
+{"ABACAVIR": 8.867005244954214, "ALEMTUZUMAB": 16.070957347974588, "ARAVA": 0.4091091159409741, "ASPARAGINASE": 50.82124813042773, "AZATHIOPRINE": 10.98273643974942, "BORTEZOMIB": 18.99505866791836, "BUSULFAN": 61.37606974074674, "CELLCEPT": 13.901631704479202, "CICLOSPORIN": 14.095508646599836, "COMBIVIR": 24.145635615040327, "CYTARABINE": 19.10429481247694, "DEXAMETHASONE": 13.3774686180267, "DOXORUBICIN": 9.996029640662906, "EFAVIRENZ": 28.53714859118922, "GANCICLOVIR": 149.11839336348416, "KALETRA": 7.165439827711759, "MERCAPTOPURINE": 56.53385097496842, "METHOTREXATE": 4.619453571683094, "MYCOPHENOLATE": 10.453757484435751, "OBINUTUZUMAB": 38.14957595414204, "RITUXIMAB": 14.393039693302445, "TRUVADA": 0.7286562202580724, "null": 0.2923336055931274}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3343.json
index 97f4e346e09..9ffbb74f7ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3343.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3343.json
@@ -1 +1 @@
-{"null": 2.23731833874971}
\ No newline at end of file
+{"ARAVA": 0.5275072473538883, "AZATHIOPRINE": 8.758435157639033, "BASILIXIMAB": 80.2799663194893, "BUDESONIDE": 2.8463618035224103, "BUSULFAN": 8.622062052116334, "CELLCEPT": 27.34715440411421, "CICLOSPORIN": 20.25608359401901, "CIDOFOVIR": 162.29863038383192, "DASATINIB": 177.66352117147068, "ENTYVIO": 8.797047455908919, "GANCICLOVIR": 163.57203200345444, "INFLIXIMAB": 71.0134433706757, "MYCOPHENOLATE": 49.00925824957943, "RINVOQ": 7.816991524822693, "SPRYCEL": 7.744914990893187, "STELARA": 2.433616137760705, "null": 0.1921512437787336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3344.json
index 28b9df4cbcb..723dcd6aeb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3344.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3344.json
@@ -1 +1 @@
-{"null": 2.1497644818720323}
\ No newline at end of file
+{"GANCICLOVIR": 140.93962494464978, "null": 0.3141018343404429}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3345.json
index 64e78d43fcf..ea7b9026e2a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3345.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3345.json
@@ -1 +1 @@
-{"CHAMPIX": 7.06368826931453, "CICLOSPORIN": 4.3973199591706, "CLOPIDOGREL": 29.458280417869894, "PLAVIX": 5.215361841865585, "TICAGRELOR": 67.19114694267986}
\ No newline at end of file
+{"BASILIXIMAB": 75.69565398023317, "CELLCEPT": 57.20328443965628, "CICLOSPORIN": 7.922765095395658, "ENTYVIO": 17.596118845037612, "GANCICLOVIR": 49.528379822420405, "KEYTRUDA": 6.346391971092817, "OPDIVO": 13.245436749455424, "REMICADE": 49.43171692235907, "SPRYCEL": 20.09020762833893, "null": 0.5579712258726509}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3346.json
index 73f71fb1f74..864d8793827 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3346.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3346.json
@@ -1 +1 @@
-{"null": 1.131952637324735}
\ No newline at end of file
+{"CELLCEPT": 47.78156918702538, "CICLOSPORIN": 16.52661816880614, "GANCICLOVIR": 168.0671433188008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3347.json
index e06f2b83529..33099c207fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3347.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3347.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 92.89624782817133}
\ No newline at end of file
+{"CELLCEPT": 46.122957188881365, "CICLOSPORIN": 23.72114021499417, "null": 0.2954297519074482}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3348.json
index a9834998e65..c14560cf571 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3348.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3348.json
@@ -1 +1 @@
-{"PEGASYS": 2.872197029649099, "null": 1.496546863711174}
\ No newline at end of file
+{"CICLOSPORIN": 25.446154302440696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3349.json
index f6ebc8b423a..880335fc859 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3349.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3349.json
@@ -1 +1 @@
-{"AVASTIN": 30.30503464692183, "I": 2341.8356390871418, "KEYTRUDA": 3.3627702920868128, "ROACTEMRA": 6.683887345713415, "SUTENT": 1.7320601853696478, "null": 1.356036684228218}
\ No newline at end of file
+{"CELLCEPT": 22.790874953703003, "CICLOSPORIN": 11.721351334885156, "COMIRNATY": 0.2790127772394333, "GANCICLOVIR": 132.7945815142211, "null": 0.3981528381845447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/335.json
index 04342d77216..38669156721 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/335.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/335.json
@@ -1 +1 @@
-{"null": 4.492837504195562}
\ No newline at end of file
+{"ENOXAPARIN": 77.93836415905481, "VAXZEVRIA": 0.9294750810088284, "null": 1.5079647297186471}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3350.json
index 9579d587045..5f76d37969d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3350.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3350.json
@@ -1 +1 @@
-{"CHLORMETHINE": 497.3030796388903, "CLOPIDOGREL": 3.484345687677149, "DENOSUMAB": 48.31706299587351, "ELIQUIS": 1.4278269516579425, "SPIRONOLACTONE": 23.037116044823573, "null": 2.833022295722777}
\ No newline at end of file
+{"ABACAVIR": 0.4361817512906402, "ADVAGRAF": 18.188974697057123, "ALEMTUZUMAB": 49.0171216962021, "AMIKACIN": 2.975346064102555, "ARANESP": 0.6777008908361877, "ARAVA": 0.1437651062032907, "ASPARAGINASE": 3.870452423293704, "ATEZOLIZUMAB": 19.062053194615693, "AZATHIOPRINE": 8.51396798154257, "BASILIXIMAB": 104.89790707437676, "BENLYSTA": 0.9338546197281185, "BIKTARVY": 1.8934816444383893, "BLINCYTO": 20.6074411769849, "BORTEZOMIB": 4.08196517042233, "BUDESONIDE": 1.3131208534260506, "BUSILVEX": 194.71393876786763, "BUSULFAN": 63.90168976221664, "CARMUSTINE": 5.424477503338146, "CASPOFUNGIN": 8.666116507746466, "CELLCEPT": 61.42889235955342, "CICLOSPORIN": 33.92312214109888, "CIDOFOVIR": 41.440928314154455, "CIMZIA": 0.2041541793730635, "COMBIVIR": 2.597041743714282, "COMIRNATY": 0.0532711937854993, "CYTARABINE": 4.791314898670538, "DARZALEX": 7.007128234211858, "DEXAMETHASONE": 3.5685349450646124, "DOXORUBICIN": 2.8757821022014247, "ENTYVIO": 4.109274553949633, "EVEROLIMUS": 14.298008998173785, "GANCICLOVIR": 60.69375850001629, "HUMAN": 3.6665860211818, "HUMIRA": 1.3038653700401126, "INFLIXIMAB": 6.990865477225045, "ISENTRESS": 4.531679682481765, "JAKAVI": 4.119715122603307, "KALETRA": 2.1117996898821976, "KEYTRUDA": 0.7398960775763309, "KYMRIAH": 3.52619971716912, "KYPROLIS": 2.827877298428241, "LAMIVUDINE": 4.344323192341329, "LEMTRADA": 1.7857157571392812, "LEVOFLOXACIN": 0.7386191519277658, "MABCAMPATH": 73.15110159435204, "MABTHERA": 3.8908767942613873, "MELPHALAN": 11.41128180888587, "MERCAPTOPURINE": 16.137830082619402, "METHOTREXATE": 2.7029256614136465, "MYCOPHENOLATE": 49.11547792337547, "NOT": 3.03590129454706, "OBINUTUZUMAB": 11.536225675524626, "OPDIVO": 1.2711846693433908, "PEGINTRON": 0.4711252115830469, "RAPAMUNE": 6.980496809845114, "REMICADE": 3.9752503136806094, "RINVOQ": 2.261166496199863, "RITUXIMAB": 4.5033452050036775, "ROTATEQ": 2.1144566738048844, "RUXOLITINIB": 15.936931540109356, "SIMPONI": 1.1442725777415796, "SOLIRIS": 2.9601174603673224, "SPIKEVAX": 0.0301192286314916, "SPRYCEL": 1.8546509425779547, "STELARA": 1.469385349516489, "TACROLIMUS": 15.157237278663734, "TEMODAL": 3.53531543677993, "TRIUMEQ": 4.6028622834965125, "VFEND": 1.8755868174032209, "XELJANZ": 0.996357230997582, "null": 0.4892899881195106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3351.json
index 980f60bd0c5..4a625c8f9ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3351.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3351.json
@@ -1 +1 @@
-{"null": 1.4013036081895904}
\ No newline at end of file
+{"ABATACEPT": 1.203411687454612, "ALEMTUZUMAB": 121.3289253303567, "AZACITIDINE": 8.56835259258077, "AZATHIOPRINE": 9.171019554030217, "BASILIXIMAB": 47.65441980889223, "BORTEZOMIB": 24.95663672358785, "BUDESONIDE": 4.35893331297208, "BUSILVEX": 27.77254114733388, "BUSULFAN": 159.49728130234237, "CARMUSTINE": 42.78955912100677, "CELLCEPT": 9.130409981533113, "CICLOSPORIN": 39.247166077405154, "CIDOFOVIR": 66.90277757766741, "COMIRNATY": 0.0359162476365468, "CYTARABINE": 9.58301553449448, "DARATUMUMAB": 43.90331700365943, "DARZALEX": 4.630246963499437, "DEXAMETHASONE": 4.997893873827275, "DOXORUBICIN": 8.609450625438626, "GANCICLOVIR": 86.31765211281565, "JAKAVI": 3.0950537163822665, "MABCAMPATH": 77.28949380753357, "MELPHALAN": 47.8561605807521, "METHOTREXATE": 4.531290874502692, "MYCOPHENOLATE": 45.46914466321498, "RITUXIMAB": 2.341852426990054, "RUXOLITINIB": 27.362096545156287, "SOLIRIS": 1.5877945712595742, "TACROLIMUS": 11.550805057576676, "THIOTEPA": 80.80282490665593, "TOFACITINIB": 67.43635724112387, "YESCARTA": 8.17698841467584, "null": 0.3134764438437334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3352.json
index 77431b23b74..f712c23f4ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3352.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3352.json
@@ -1 +1 @@
-{"ARANESP": 1.0967566833854108, "AUBAGIO": 1.4634334920165142, "AVASTIN": 5.4807383798835305, "AZATHIOPRINE": 1.0230843627834798, "BONVIVA": 2.826052122637696, "BOSULIF": 1.8354560753482576, "BRAFTOVI": 1.5264845961192377, "BRILIQUE": 4.592203059087188, "BUPRENORPHINE": 1.1831321642194148, "BYDUREON": 1.9736404403984091, "BYETTA": 1.9508138598800304, "CABOMETYX": 1.8818687537004928, "CAELYX": 3.1229079656057785, "CELECOXIB": 2.0892452753969346, "CELLCEPT": 2.777072423598667, "CHAMPIX": 1.6214489065734403, "CICLOSPORIN": 1.920869301624976, "CLOPIDOGREL": 10.656456292134433, "COSENTYX": 1.497737922655508, "DARUNAVIR": 8.859596542922949, "EFIENT": 8.857985496521357, "ELIQUIS": 3.9705309077916944, "EVEROLIMUS": 3.605499057521736, "EXJADE": 4.164796609067894, "FORSTEO": 1.7133381552228686, "IBUPROFEN": 3.9394986871177498, "INLYTA": 1.7833007936640255, "IRESSA": 2.239559524781864, "ISENTRESS": 3.526647371371422, "JAKAVI": 2.672390243200144, "JANUMET": 2.8011254259936016, "JANUVIA": 2.668344078212165, "KEYTRUDA": 1.3529094586916772, "MEKINIST": 1.220015579322513, "METHOTREXATE": 1.486095421436057, "MICARDIS": 1.5805850068956275, "NEXAVAR": 3.158396165668956, "ORENCIA": 11.331536926191276, "PLAVIX": 12.071694248665333, "PRADAXA": 5.929867627300556, "RINVOQ": 1.3934761949111871, "ROACTEMRA": 1.2428245572630214, "SPRYCEL": 1.5711441597258873, "SUTENT": 2.0826286581179727, "TACROLIMUS": 3.836088753065124, "TASIGNA": 1.4988427812892124, "TICAGRELOR": 7.5418794805671965, "VICTOZA": 1.5569460625950446, "VOTRIENT": 1.9217400431286813, "XARELTO": 5.430387260288251, "XELJANZ": 2.1763801075128164, "null": 1.8011032449198856}
\ No newline at end of file
+{"ABACAVIR": 27.96341927510422, "MYCOPHENOLATE": 97.57945056011022, "null": 0.2752261779930195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3353.json
index c31638ef938..7234337ff86 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3353.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3353.json
@@ -1 +1 @@
-{"ALIMTA": 1.9042892542077905, "AVASTIN": 3.934102210524969, "BRILIQUE": 10.162808738602664, "CELECOXIB": 4.920746983024274, "CELLCEPT": 2.2594542238576354, "CLOPIDOGREL": 14.20601063714873, "EFIENT": 35.39529556850933, "ELIQUIS": 8.478055216677836, "EXJADE": 1.1456899556069322, "FIRDAPSE": 8.53966430168686, "IBUPROFEN": 3.7354745245198737, "ISCOVER": 115.956823658567, "LIXIANA": 7.031904197190437, "NEXAVAR": 4.340003391782286, "PLAVIX": 34.883538878970114, "SUTENT": 1.3072484830718645, "TICAGRELOR": 20.12180399203093, "XARELTO": 17.499262302920044, "null": 1.7596771120486847}
\ No newline at end of file
+{"CELLCEPT": 82.2140457926085, "GANCICLOVIR": 473.6931449373272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3354.json
index 40906845589..2e6021336e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3354.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3354.json
@@ -1 +1 @@
-{"null": 1.4579362932943845}
\ No newline at end of file
+{"CICLOSPORIN": 37.47446548505119, "null": 0.4538419556163846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3355.json
index 84fb49929fb..67faba9b295 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3355.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3355.json
@@ -1 +1 @@
-{"PLAVIX": 4.852684293276983, "SUTENT": 2.268310548055036, "null": 1.5286634824694103}
\ No newline at end of file
+{"AZATHIOPRINE": 9.325967781567764, "BASILIXIMAB": 38.7675211700053, "BUSULFAN": 59.3062762448387, "CELLCEPT": 87.65409574358912, "CICLOSPORIN": 27.283195677557025, "COMIRNATY": 0.0670328177958509, "GANCICLOVIR": 14.490029374334371, "METHOTREXATE": 7.633605774737127, "MYCOPHENOLATE": 13.55302129206948, "null": 0.6814893233958442}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3356.json
index a05de952241..bced0828f55 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3356.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3356.json
@@ -1 +1 @@
-{"JANUMET": 22.944068092231003, "RIBAVIRIN": 38.79697485049733}
\ No newline at end of file
+{"BUSULFAN": 1226.9525863978813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3357.json
index f9569482000..f19778fcec4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3357.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3357.json
@@ -1 +1 @@
-{"JAKAVI": 26.32532128778129, "NEXAVAR": 41.71983923940159}
\ No newline at end of file
+{"ABATACEPT": 1.429573170782268, "ALEMTUZUMAB": 69.65331113582533, "ASPARAGINASE": 42.33850662187424, "AZATHIOPRINE": 11.484871631277423, "BASILIXIMAB": 110.03705505900382, "BUDESONIDE": 1.2734349408257584, "BUSULFAN": 146.80283649606665, "CELLCEPT": 48.18800494081823, "CICLOSPORIN": 22.043960598450624, "CYTARABINE": 4.87524639858387, "GANCICLOVIR": 174.12577136506067, "HUMAN": 7.950372095493082, "INFLIXIMAB": 11.528473410068775, "MELPHALAN": 34.398773285034835, "METHOTREXATE": 4.042054596582786, "MYCOPHENOLATE": 67.58303911517848, "RITUXIMAB": 5.025089383707743, "SOLIRIS": 4.225045239394994, "TACROLIMUS": 20.03520013050089, "null": 0.3238190370691299}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3358.json
index 624170e33ad..cf1b1160194 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3358.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3358.json
@@ -1 +1 @@
-{"null": 1.731601702195374}
\ No newline at end of file
+{"AFINITOR": 1.0397264850869656, "ALEMTUZUMAB": 5.124383144539058, "ALIMTA": 2.4654490353272247, "AMIKACIN": 3.5828262500426264, "ARAVA": 0.3154333455695428, "ASPARAGINASE": 5.337441354878362, "AVASTIN": 2.898834946093108, "AXICABTAGENE": 23.77286760434672, "AZACITIDINE": 60.83267129884074, "AZATHIOPRINE": 2.1242116410203, "BASILIXIMAB": 6.101796507160331, "BEVACIZUMAB": 1.789114721495004, "BLINATUMOMAB": 28.97982713359016, "BORTEZOMIB": 18.857400337373917, "BOSULIF": 8.927289441275837, "BOSUTINIB": 23.926246810203384, "BUSULFAN": 5.661172637158931, "CAPECITABINE": 5.291717628158027, "CARFILZOMIB": 23.23546901622097, "CARMUSTINE": 24.784157386503143, "CELLCEPT": 2.9700050090049555, "CICLOSPORIN": 2.3421271630528997, "CLADRIBINE": 6.400501630607218, "COMIRNATY": 0.0111551050293026, "CYTARABINE": 16.64986429444131, "DARZALEX": 10.730610068526158, "DASATINIB": 9.561644754730668, "DEXAMETHASONE": 9.800416036175008, "DOCETAXEL": 6.392497593129625, "DOXORUBICIN": 22.50289046466196, "EXJADE": 1.5695463187070389, "FASLODEX": 2.9875819575683225, "FILGRASTIM": 13.262973101743931, "FULVESTRANT": 4.131083408441936, "GANCICLOVIR": 15.086489811961677, "GAZYVARO": 9.66726148813115, "GLIVEC": 5.40006783835651, "IBRANCE": 8.632038655718587, "IBRUTINIB": 16.690475288569477, "ICLUSIG": 21.95029798027997, "IMATINIB": 26.3497850447522, "IRINOTECAN": 2.532114834186733, "JAKAVI": 12.694927732883158, "KEYTRUDA": 2.2101440765197244, "KYMRIAH": 29.9609563353194, "KYPROLIS": 14.90779378283181, "LEFLUNOMIDE": 4.372063398814213, "LENALIDOMIDE": 13.417129943178928, "LEVETIRACETAM": 0.8608038650435367, "LONSURF": 13.801014738541324, "LYNPARZA": 1.8044173677830653, "MABTHERA": 12.43871708505698, "MERCAPTOPURINE": 7.541955418989596, "METHOTREXATE": 1.3299662653469098, "NEXAVAR": 1.1804153262292365, "NILOTINIB": 20.309626323558398, "NINLARO": 4.037405475686255, "OPDIVO": 1.0635319330807325, "PACLITAXEL": 7.43047458529351, "PEGASYS": 1.0344695943243036, "PEGINTERFERON": 4.200669112548444, "PEGINTRON": 1.5058641586451875, "PEMBROLIZUMAB": 2.7189619777506304, "PEMETREXED": 8.654681846266586, "POMALIDOMIDE": 17.33861021906855, "REVLIMID": 4.995875148397106, "RIBAVIRIN": 1.70131819473566, "RITUXIMAB": 9.093695647179546, "RUBRACA": 2.254231733222221, "RUXOLITINIB": 25.40575055785961, "RYDAPT": 26.640344848081067, "SIMPONI": 0.3770296089807222, "SOLIRIS": 1.4970560642664126, "SPRYCEL": 14.179689451583016, "SUTENT": 1.3724314930552357, "TASIGNA": 7.470764245920069, "TEGAFUR": 19.392637927828638, "TEMODAL": 6.188900948772196, "TEMOZOLOMIDE": 4.79416271297974, "THALIDOMIDE": 3.35882551348306, "TOPOTECAN": 12.521510765777316, "TRODELVY": 3.51489891633312, "VENCLYXTO": 28.754452480772773, "VENETOCLAX": 62.09923479266813, "VYXEOS": 33.660536962413545, "XELJANZ": 0.3353368559725429, "XELODA": 3.4029658169104597, "XOFIGO": 3.028617536857068, "YESCARTA": 31.30585050198848, "null": 0.6811306096768124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3359.json
index 8b729bfcf7b..0d98a64d888 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3359.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3359.json
@@ -1 +1 @@
-{"AIMOVIG": 1.1450089822785323, "AMIKACIN": 1.5612642572403197, "AMINOSALICYLIC": 3.522877254108869, "AUBAGIO": 1.1684293867763929, "AVASTIN": 1.0630325960929154, "BEDAQUILINE": 1.9909363475718689, "BENLYSTA": 1.1048537825215543, "BETMIGA": 2.879069385533123, "BONVIVA": 6.879406770703405, "BOSULIF": 1.3424344222439777, "BRAFTOVI": 1.6580155276226185, "BRILIQUE": 2.0756034901804195, "BRINTELLIX": 1.092209220571761, "BYDUREON": 1.0545809421558452, "BYETTA": 5.467658728013177, "CELECOXIB": 4.653093891295279, "CELLCEPT": 1.607123246264314, "CHAMPIX": 1.308898189991133, "CICLOSPORIN": 1.1799931256095189, "CLOPIDOGREL": 2.9372411127720413, "COAPROVEL": 1.5428316854910296, "COTELLIC": 2.358326745641816, "CYTARABINE": 1.4809759876968098, "DACLATASVIR": 5.466515698962911, "DUKORAL": 29.63207932518932, "EFAVIRENZ": 2.4523945742282023, "ELIQUIS": 1.234015737223888, "ENBREL": 1.1065596473545745, "ESOMEPRAZOLE": 1.4270468535611691, "EVISTA": 2.2956621388249583, "EXFORGE": 1.9413306393185945, "EXJADE": 2.345159660122176, "FASLODEX": 1.3456650481750685, "FIRDAPSE": 1.5753731918637273, "FORSTEO": 2.2396138309663254, "GALVUS": 2.2698036122980376, "GARDASIL": 1.6088398433499338, "HERCEPTIN": 1.0518621280534322, "IBUPROFEN": 1.9042901901613527, "INCIVO": 1.0455687380686156, "IPILIMUMAB": 2.79945464102805, "JANUMET": 3.29039949417512, "JANUVIA": 2.674295690074475, "KAFTRIO": 1.786248549045062, "KALETRA": 2.915328306687168, "KEYTRUDA": 1.528590163364013, "KISQALI": 2.2851938233121345, "LEVOFLOXACIN": 1.303669540877174, "LIXIANA": 1.1963590086015468, "LYNPARZA": 1.1042451930453228, "LYRICA": 1.485834293821127, "METHOTREXATE": 1.842928792239836, "OPDIVO": 2.026011428351472, "PANTOPRAZOLE": 2.536647848078964, "PEGASYS": 1.0723907823967844, "PEGINTRON": 1.1759625513571714, "PEMBROLIZUMAB": 2.207693137752005, "PLAVIX": 3.897352625413544, "PRADAXA": 2.812516685960521, "REMICADE": 1.6264278835799773, "ROACTEMRA": 1.0516654443833369, "RUBRACA": 1.378876416720249, "RYBELSUS": 3.3990479968774543, "SAXENDA": 8.102702654106327, "SPRYCEL": 1.662564031165188, "SUFENTANIL": 3.1270129199642613, "SUTENT": 2.101002121416945, "TRULICITY": 1.8787365839610493, "UNSPECIFIED": 5.724904094990235, "VICTOZA": 3.0652473524924875, "VIMPAT": 1.3476512249423152, "XARELTO": 1.851556394746916, "XELJANZ": 1.0813521839852416, "XYREM": 2.142776586231483, "ZOSTAVAX": 1.06567833900495, "ZYPREXA": 1.076016667778483, "null": 1.429661562379858}
\ No newline at end of file
+{"TOCILIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/336.json
index 6b95c167ee1..fe5957d8eb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/336.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/336.json
@@ -1 +1 @@
-{"BUSULFAN": 1.2212039832812052, "CARMUSTINE": 1.212046389536792, "COMIRNATY": 12.423260167497116, "ELLAONE": 2.275766905749496, "ERENUMAB": 2.744479301086959, "ESMYA": 17.975812491780623, "EVRA": 2.704875313116577, "GARDASIL": 1.319542693656402, "INVEGA": 7.892499593476063, "REBIF": 3.167374425977623, "RINVOQ": 1.3165279733463608, "RYEQO": 24.40258963306568, "SPIKEVAX": 1.992043425131432}
\ No newline at end of file
+{"ABATACEPT": 0.7088709878779206, "ADALIMUMAB": 3.64605433114416, "AFINITOR": 0.3580910470427529, "ALEMTUZUMAB": 1.128071103300771, "ALIMTA": 1.122873910523572, "ANAKINRA": 10.04349169260012, "ARAVA": 0.1213949174436545, "ATAZANAVIR": 7.977183697237856, "AVAMYS": 2.547652331140132, "AXITINIB": 11.390618423432263, "BAVENCIO": 29.40566573794465, "BENLYSTA": 0.6628377003857919, "BRAFTOVI": 2.622236908451458, "BUDESONIDE": 6.68986071186321, "CABOMETYX": 9.045534272557177, "CELLCEPT": 0.6290454499906212, "CICLOSPORIN": 0.5198644533160177, "COMIRNATY": 0.0708857788854307, "COSENTYX": 0.5876195040335521, "CYMBALTA": 0.5073118332053173, "CYTARABINE": 0.8579335460267048, "DEXAMETHASONE": 2.760800826596552, "DOXORUBICIN": 1.845891541209162, "DULOXETINE": 2.366150027881064, "EMPAGLIFLOZIN": 10.272192357951718, "EMTRICITABINE": 3.258032587139684, "ENBREL": 0.4041454048190663, "ENOXAPARIN": 2.243327091974564, "FASENRA": 2.895647095760036, "FENTANYL": 0.4431959254733392, "FLUTICASONE": 4.049743445521332, "GARDASIL": 0.5241310383169682, "HYDROCORTISONE": 15.245439406787762, "INLYTA": 4.534322146058072, "INSULIN": 0.6515585639971, "IPILIMUMAB": 27.10040061042941, "IRON": 5.865631365929076, "JARDIANCE": 2.496720920519916, "KALETRA": 3.815153161618192, "KEPPRA": 0.3457853540336059, "KEYTRUDA": 49.96132410392669, "KIVEXA": 8.495009555188792, "LENVIMA": 8.930942728376815, "LIBTAYO": 12.824907575127687, "LOPINAVIR": 7.029707143190917, "LYRICA": 0.8255194639828888, "LYSODREN": 44.281390988049765, "MEPOLIZUMAB": 4.266572821861256, "MITOTANE": 143.74734735871854, "NORVIR": 12.192195844638164, "NOXAFIL": 3.9711009107998536, "NUCALA": 1.8655811630754997, "OMALIZUMAB": 1.0632376236031151, "OPDIVO": 89.26868147766206, "PEGASYS": 0.1818151155902168, "PEMBROLIZUMAB": 12.208079834863709, "RELVAR": 5.57433466154503, "RITONAVIR": 47.04643325988366, "SPIKEVAX": 0.0249823698330184, "SUBOXONE": 0.4098554539167832, "SUTENT": 0.7259131638950848, "TOZINAMERAN": 0.0684693501717607, "TRUVADA": 0.2609139486162712, "VAXZEVRIA": 0.0465200678210427, "VFEND": 1.5889864494253756, "VORICONAZOLE": 2.0674348526239985, "XELJANZ": 0.3324493944851553, "XOLAIR": 1.148627775928159, "XTANDI": 0.5723626902450966, "YERVOY": 20.863380297241548, "null": 0.5940997790986716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3360.json
index 5101b0a556a..9e02d0505cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3360.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3360.json
@@ -1 +1 @@
-{"ARANESP": 1.5844943940937062, "BRILIQUE": 7.441086493482119, "BYETTA": 1.8424253827023935, "CEFUROXIME": 146.15983979393485, "CLOPIDOGREL": 17.864335142966205, "COSENTYX": 1.288989708789077, "ELIQUIS": 2.71242916780463, "HARVONI": 4.275375886103681, "I": 778.2955641308783, "IBUPROFEN": 2.544856480472044, "PLAVIX": 12.56743173742952, "TICAGRELOR": 18.46889262153336, "null": 2.379954071165153}
\ No newline at end of file
+{"COMIRNATY": 1.3694287568569803, "null": 0.4894537929896228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3361.json
index 2dd73561ebc..93181296f43 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3361.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3361.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 611.4482253764104}
\ No newline at end of file
+{"null": 0.2370482785597451}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3362.json
index 6deccb19b89..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3362.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3362.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 6.033586441626283, "ELIQUIS": 4.746200922300627, "ISCOVER": 228.4518689559682, "PEGASYS": 1.1101985318529568, "PLAVIX": 16.090567457107856, "XARELTO": 11.77387208209341, "null": 1.7864408558454987}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3363.json
index 85dfc00ac02..e0ff7a001e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3363.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3363.json
@@ -1 +1 @@
-{"null": 1.5582295313705885}
\ No newline at end of file
+{"HUMIRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3364.json
index 0ae750de607..556f0a9add2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3364.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3364.json
@@ -1 +1 @@
-{"null": 1.6649591610408037}
\ No newline at end of file
+{"null": 1.0172532373180796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3365.json
index f1dff8d44df..c43239e8865 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3365.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3365.json
@@ -1 +1 @@
-{"ACLIDINIUM": 31.08316455881353, "ALEMTUZUMAB": 3.075669665353677, "ALIMTA": 1.1335698089637405, "AMINOSALICYLIC": 6.3774856230606485, "BEDAQUILINE": 4.7031476010580295, "BENLYSTA": 1.246853643739671, "BUSULFAN": 1.2475536394364075, "BYDUREON": 1.1717063596941035, "BYETTA": 3.131032720511448, "CAPECITABINE": 1.5335456412935706, "CELLCEPT": 5.307408492740439, "CRIZOTINIB": 24.71402496274566, "DELAMANID": 14.736930203599782, "DOCETAXEL": 1.520679548753258, "EMPAGLIFLOZIN": 3.326236460959717, "EXJADE": 1.2929654668977408, "FASENRA": 1.5194716366870422, "FASLODEX": 1.239648009410297, "FIRDAPSE": 4.008595158741052, "FLUTICASONE": 10.225340854419931, "FORSTEO": 3.731922840555556, "FORXIGA": 2.783675872716062, "GARDASIL": 2.07822184601995, "INCIVO": 3.7179323155082935, "INFANRIX": 11.904862449586364, "INVOKANA": 5.524572912058302, "IPILIMUMAB": 1.5247506152627472, "JANUMET": 1.3142189638214945, "JANUVIA": 1.0297742476469132, "JARDIANCE": 5.289713761698752, "LEVEMIR": 1.2688260787431878, "METHOTREXATE": 2.212072920442408, "MICARDIS": 1.5918363270076583, "MMRVAXPRO": 2.365124807172967, "OFEV": 1.0545293225232886, "OMALIZUMAB": 1.096977530386893, "OPSUMIT": 1.1903637050219678, "PEGINTRON": 1.5378425960037805, "PREVENAR": 5.923794995236322, "PROTOPIC": 38.22338975982975, "ROACTEMRA": 1.7010617636220005, "ROTASHIELD": 134.8481763047518, "ROTATEQ": 44.20771096311233, "SAXENDA": 4.977572882944337, "SIMPONI": 1.0463211756528248, "SOLIRIS": 2.526082567188653, "SPINRAZA": 3.977676834297863, "STELARA": 1.3834897041838523, "SYNAGIS": 10.611421096914691, "SYNFLORIX": 49.50427881908052, "TRACLEER": 1.3752844470919323, "TREMFYA": 2.77382100238822, "TRULICITY": 1.9302855123711269, "TWINRIX": 2.66917965920307, "VICTOZA": 3.2234851484166223, "XELJANZ": 1.5675877227969002, "XOLAIR": 1.2304491132859348, "ZYPREXA": 1.0721011284231583, "null": 1.1642265977367396}
\ No newline at end of file
+{"CAELYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3366.json
index a21cce612b0..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3366.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3366.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 189.560551622362, "CICLOSPORIN": 24.366343960983684}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3367.json
index 8689ac01c15..1c196fb62ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3367.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3367.json
@@ -1 +1 @@
-{"null": 1.625130602296902}
\ No newline at end of file
+{"COMIRNATY": 1.8999937102515292, "null": 0.7437140097535307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3368.json
index cc3afe1e482..7814f63a18e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3368.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3368.json
@@ -1 +1 @@
-{"ENTYVIO": 30.839229154454127, "null": 1.208516124031081}
\ No newline at end of file
+{"null": 1.03624784347871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3369.json
index 4d59b80d5ea..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3369.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3369.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 36.64665719727967, "ASPARAGINASE": 96.65176109842196, "BUSULFAN": 23.718490400702525, "CELLCEPT": 8.823006580444792, "CICLOSPORIN": 7.3901245090569585, "CYTARABINE": 13.611437944761864}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/337.json
index f779bb8f48e..389db367297 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/337.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/337.json
@@ -1 +1 @@
-{"CICLOSPORIN": 40.18468625699976}
\ No newline at end of file
+{"BYETTA": 27.44076390190085, "JANUMET": 51.44387742601574, "JANUVIA": 31.49953015406459, "null": 0.605258142364816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3370.json
index 0a46fe887d6..c9923e0da71 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3370.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3370.json
@@ -1 +1 @@
-{"PREVENAR": 29.039990802144693, "ROTATEQ": 3799.2644022541904, "SYNAGIS": 11.128835654804124}
\ No newline at end of file
+{"ASPARAGINASE": 43.55443140879772, "DOCETAXEL": 55.20843720460139, "null": 3.989931643546606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3371.json
index 2e89d0b42b0..2e5c67c207a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3371.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3371.json
@@ -1 +1 @@
-{"ARAVA": 2.3186112870267075}
\ No newline at end of file
+{"null": 3.862661238590867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3372.json
index 4cc9ef2441c..d9293e926cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3372.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3372.json
@@ -1 +1 @@
-{"null": 2.060661229853793}
\ No newline at end of file
+{"ADALIMUMAB": 2.575086086936821, "CIMZIA": 4.663934901016317, "COMIRNATY": 0.2061954488873211, "COSENTYX": 91.00424019092247, "ENBREL": 26.82559128909287, "HUMIRA": 9.634121067953828, "METHOTREXATE": 15.32751110512211, "STELARA": 12.541443658184368, "null": 0.0753948748593834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3373.json
index 16bca8fe039..996dc8bde27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3373.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3373.json
@@ -1 +1 @@
-{"ADALIMUMAB": 5.794775056059652, "AMBRISENTAN": 20.69488058713773, "ANAKINRA": 2.91403498341792, "APIDRA": 1.91140709249839, "AUBAGIO": 1.0319802903220214, "AVAMYS": 5.184856361007884, "AZATHIOPRINE": 3.2424489844519577, "BENLYSTA": 3.293254720976102, "BOSULIF": 6.587175195083663, "BYDUREON": 4.597093660964562, "BYETTA": 1.489347682440225, "CELLCEPT": 1.0558076920110742, "CIMZIA": 2.378696337916613, "DENOSUMAB": 16.33635949422196, "ENTYVIO": 2.3124727748613227, "EXJADE": 2.065526039016758, "HIZENTRA": 5.274418581368087, "HUMALOG": 2.176071078518933, "IBRANCE": 1.808958908647656, "JARDIANCE": 1.4129230481424615, "METHOTREXATE": 1.215849205137076, "OMALIZUMAB": 3.706093995091312, "OPSUMIT": 3.641284591439321, "PEGASYS": 1.5803181149995345, "REMICADE": 6.554932603680343, "ROTATEQ": 5.232300856243053, "SIMPONI": 1.5512328337336, "SOLIRIS": 4.5738984238466704, "SPINRAZA": 8.37322402749472, "STELARA": 1.3056684055977772, "SYNAGIS": 3.5622295088234366, "TRACLEER": 4.5318037632284405, "TRULICITY": 3.133622734061845, "VICTOZA": 3.322073186645235, "XELJANZ": 3.5509495755776435, "XOLAIR": 2.138554759247791, "null": 1.1770778469650174}
\ No newline at end of file
+{"GARDASIL": 13.313539013643542, "ROTATEQ": 105.22214826210984, "null": 0.6774515293431573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3374.json
index cede950f07a..5b2a2d69f1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3374.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3374.json
@@ -1 +1 @@
-{"LUTATHERA": 1591.4611163225388}
\ No newline at end of file
+{"COMIRNATY": 0.2123129638984734, "SPIKEVAX": 0.295983353140356, "VAXZEVRIA": 0.1169060218013391, "null": 4.9814732339658425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3375.json
index 4e7a14b0ef4..7bcd4a68cd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3375.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3375.json
@@ -1 +1 @@
-{"BYETTA": 97.0623562272919, "JANUVIA": 156.3101028095204}
\ No newline at end of file
+{"COMBIVIR": 87.95008923313456, "null": 1.4481540532943753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3376.json
index 1aac1c254bf..ff06a07aa5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3376.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3376.json
@@ -1 +1 @@
-{"null": 1.2243969595857331}
\ No newline at end of file
+{"COMIRNATY": 0.3628329585211889, "VAXZEVRIA": 0.4246472858774358, "null": 1.5061616914689815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3377.json
index 507b4e81e0a..830a139bba5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3377.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3377.json
@@ -1 +1 @@
-{"IRINOTECAN": 173.61877673092252}
\ No newline at end of file
+{"HUMALOG": 51.43910803475495, "LANTUS": 18.77320171749247}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3378.json
index 2647ae528ca..ea27c86d019 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3378.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3378.json
@@ -1 +1 @@
-{"BUMETANIDE": 693.0067012441299, "CLOPIDOGREL": 8.921760517344792, "ELIQUIS": 8.310503277044662}
\ No newline at end of file
+{"BRINTELLIX": 5.254104222801221, "CHAMPIX": 6.5248955498155246, "COMIRNATY": 0.5017655574409011, "KEPPRA": 4.344824325148146, "LANTUS": 1.940845532324956, "SPIKEVAX": 0.2285571199153422, "VAXZEVRIA": 0.4986644872832727, "null": 1.6028007657853314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3379.json
index 295fcd1a385..084826d887c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3379.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3379.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.5014332224631324, "GARDASIL": 9.269911676393484, "null": 1.9022266925974016}
\ No newline at end of file
+{"ABILIFY": 0.4399797999211872, "ACALABRUTINIB": 57.3306409342533, "ACETYLSALICYLIC": 38.75254920919572, "ADALIMUMAB": 0.0656696517367579, "ADCIRCA": 1.6679256401212252, "AIMOVIG": 1.130413082916378, "ALIMTA": 0.5973564723870479, "AMIKACIN": 20.19182224680455, "AMINOSALICYLIC": 1.1154387019989214, "APIDRA": 0.5738608873513241, "APIXABAN": 0.2651421829445762, "ARAVA": 0.40187827817669, "ATRIPLA": 0.0429911366444245, "AUBAGIO": 0.233357836288118, "AVAMYS": 1.0469115570656575, "AVANDIA": 0.2009354323672326, "AVASTIN": 0.4379375929630597, "BEDAQUILINE": 2.002107846030778, "BENLYSTA": 0.5929999904363857, "BIKTARVY": 1.5834696382861675, "BUMETANIDE": 3.171814098222176, "BUPRENORPHINE": 0.6645842506500641, "BYDUREON": 0.5277223358207652, "BYETTA": 0.5004481483013006, "CELLCEPT": 0.7856228614662875, "CHAMPIX": 0.5448264325553839, "CIALIS": 2.872432561702933, "CICLOSPORIN": 0.2235418383254799, "CIMZIA": 1.6871861717125367, "CLOPIDOGREL": 0.446665497875793, "COAPROVEL": 0.9798524952773902, "COMIRNATY": 0.6298783873101474, "COSENTYX": 0.6013740207733617, "CYMBALTA": 0.3906846861747698, "DEXAMETHASONE": 0.58951421093871, "DOCETAXEL": 0.396649427897612, "ELIQUIS": 0.8619556087069957, "ENBREL": 0.2150151371328854, "ENTRESTO": 0.6037750671209612, "EXFORGE": 2.0503002588351293, "EXJADE": 4.731883978338439, "EYLEA": 0.5845791703708854, "FASENRA": 1.3859106893089723, "FASLODEX": 0.453791875936509, "FORSTEO": 0.7808123339535421, "GARDASIL": 0.9159221595026285, "HARVONI": 0.6097658191819493, "HUMALOG": 1.5546630812161668, "HUMIRA": 1.0375537253897311, "HYDROCORTISONE": 0.7747479291374759, "IBRANCE": 2.920111301956074, "IBUPROFEN": 0.6574924564540475, "INCIVO": 0.6071496878071596, "INLYTA": 0.7586008665518045, "INSULIN": 0.6016970148726096, "INTRONA": 2.540927256395358, "JAKAVI": 0.3596864050285108, "JANUMET": 0.5845899624438877, "JANUVIA": 0.7457801270836966, "JARDIANCE": 0.7736268191985003, "KEPPRA": 0.4476072340848473, "KEYTRUDA": 0.3685296967542889, "LAMIRA": 48.54162470990339, "LANTUS": 1.6005930100913237, "LEVEMIR": 1.0953688381550677, "LEVETIRACETAM": 0.2699836429622205, "LEVOFLOXACIN": 0.6385035862421767, "LYRICA": 0.9816857497738176, "MEKINIST": 0.5883408795214037, "MEPOLIZUMAB": 0.5265828231503661, "METHOTREXATE": 0.9817591217801208, "MODERNA": 0.7103627161579021, "NAGLAZYME": 1.5236128562382367, "NEULASTA": 0.5713863264140429, "NEXAVAR": 0.6392423976126297, "NOT": 1.066677971371263, "NUCALA": 0.7474260852631811, "OLANZAPINE": 0.2099709058736618, "OPDIVO": 0.5608430907100633, "OPSUMIT": 0.6283212808799858, "PEGASYS": 2.204780301795479, "PEGINTRON": 2.2004023581835623, "PLAVIX": 0.270660877058956, "RAPAMUNE": 1.1732377571322552, "REBETOL": 1.7530516508627203, "REVATIO": 4.578278852315695, "RIBAVIRIN": 0.7487853912704533, "ROACTEMRA": 0.3587320840543143, "SHINGRIX": 1.860801138537111, "SILDENAFIL": 1.816429426809652, "SIMPONI": 0.7508896449978931, "SOLIRIS": 0.3849776713727149, "SOVALDI": 1.4959224440777237, "SPIKEVAX": 0.6137726532395315, "SPRYCEL": 0.8263969241225483, "STELARA": 0.4956352826580587, "SUTENT": 0.7406925228779428, "TAGRISSO": 0.9765684929535652, "TAMIFLU": 0.761812235031969, "TASIGNA": 1.2585520574828228, "THIOTEPA": 18.3052108148416, "TIVICAY": 2.841806514409853, "TOBRAMYCIN": 7.869634104270363, "TOVIAZ": 1.9511348800522543, "TOZINAMERAN": 2.364032310787088, "TRACLEER": 0.698857025365268, "TREMFYA": 0.916689992626336, "TRULICITY": 1.1868155318946978, "VAXZEVRIA": 0.5983357336307676, "VFEND": 1.9802630142143391, "VIAGRA": 10.85084725184446, "VOTRIENT": 0.3988082067458713, "XELJANZ": 2.088310516083637, "XOLAIR": 0.6624034996951033, "XTANDI": 0.7409116058217368, "ZOSTAVAX": 9.557274388913802, "ZYPREXA": 0.3190453141024099, "null": 1.2349306953807175}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/338.json
index 7ad9988e429..d1f3d776180 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/338.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/338.json
@@ -1 +1 @@
-{"COMTAN": 287.49336409222485, "OLANZAPINE": 48.025924027778274, "null": 1.2421572210047716}
\ No newline at end of file
+{"null": 0.9142753825506328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3380.json
index 0aa875dc2fa..a5528755290 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3380.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3380.json
@@ -1 +1 @@
-{"COSENTYX": 11.43218775067814, "null": 1.1850542976179343}
\ No newline at end of file
+{"AMIKACIN": 28.48454022944031, "AMINOSALICYLIC": 5.612989687967537, "COMIRNATY": 0.4387357124852414, "DEXAMETHASONE": 3.0112823143152725, "EXJADE": 4.165618786056417, "GARDASIL": 1.8647706501726893, "KEYTRUDA": 1.4270289940662788, "PEGASYS": 1.3666867400608254, "REVATIO": 9.409931976434848, "SPIKEVAX": 0.4686545882559494, "TOZINAMERAN": 1.1490222124709677, "VAXZEVRIA": 0.278507735123857, "VFEND": 6.348587119684815, "ZOSTAVAX": 3.220573672361325, "null": 1.4526512672285192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3381.json
index a353f87ede2..72da03d06de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3381.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3381.json
@@ -1 +1 @@
-{"ELIQUIS": 1.7263907509253744, "INSULIN": 3.92895532668363, "LANTUS": 2.4089734502361937, "SIMPONI": 2.1312442902470017, "STELARA": 2.739923497308524, "SUTENT": 1.0780738022368517, "null": 5.897675203799092}
\ No newline at end of file
+{"null": 2.5771996762970018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3382.json
index a18c94993c2..3505bdaf88c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3382.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3382.json
@@ -1 +1 @@
-{"ABATACEPT": 6.275994403508665, "ACETAMINOPHEN": 14.64563067031852, "ACETYLSALICYLIC": 13.93005290067236, "ADALIMUMAB": 4.450290548625008, "ADCIRCA": 1.4267917079458283, "ADEMPAS": 1.5868040909904226, "ALISKIREN": 11.276925693241903, "AMIKACIN": 2.2059134587911218, "AMINOSALICYLIC": 1.3399906792439928, "ANAKINRA": 1.5618961519958103, "ANTIBIOTICS": 1.7308274453375163, "APREMILAST": 3.0133072435261083, "APREPITANT": 21.184427968686084, "ARAVA": 4.319061886164499, "AUBAGIO": 2.7487596924825333, "AVASTIN": 1.2594570252664736, "AZATHIOPRINE": 3.5807988433284117, "BARACLUDE": 1.311523459129326, "BELIMUMAB": 2.65490482008081, "BEVACIZUMAB": 2.668493146814696, "BIKTARVY": 3.0949681250574987, "BONVIVA": 1.9738401976337523, "BOSULIF": 2.506457409876476, "BRINTELLIX": 1.6260366292066173, "BRUKINSA": 3.1733214865609853, "BYDUREON": 1.4776060192518348, "BYETTA": 1.2098704067790906, "CAPECITABINE": 1.195863985181853, "CARFILZOMIB": 2.1598380373926997, "CELECOXIB": 3.429791496373627, "CELLCEPT": 1.9169780509834933, "CHAMPIX": 1.1537524770644634, "CHLORHEXIDINE": 21.620562940783103, "CIMZIA": 8.255972126511143, "CINACALCET": 4.766259927610637, "COMBIVIR": 1.3483652662864534, "COSENTYX": 2.402319398403429, "DELAMANID": 1.5013038484083547, "DENOSUMAB": 1.6928946663715445, "DESCOVY": 2.8252742011729484, "DOXORUBICIN": 1.3735941723034484, "DULAGLUTIDE": 2.0441169085705804, "EFAVIRENZ": 1.1088459172724603, "ELIQUIS": 1.7552178070459707, "ENBREL": 2.0760346095851965, "ENTECAVIR": 1.4740269040850689, "ENTYVIO": 1.1975269893625855, "ENZALUTAMIDE": 2.8013964642198563, "ESBRIET": 5.004814634191738, "ETANERCEPT": 2.758593164817002, "EVISTA": 1.8896730605869076, "EXJADE": 1.9753381221122577, "FAMPYRA": 3.2073882133521487, "FORSTEO": 1.710122466098814, "GALAFOLD": 2.9483016541245406, "GALVUS": 1.456659209968665, "GLIVEC": 1.284062909979525, "GLYCOPYRRONIUM": 1.333609289213749, "HERCEPTIN": 1.103834107344133, "HUMIRA": 2.3552203378368177, "I": 45.21604268733434, "IBRANCE": 1.34681204181705, "IBUPROFEN": 1.1720623471616405, "INLYTA": 1.0073744670144666, "IRINOTECAN": 1.628144147688832, "ISENTRESS": 1.0103875195935454, "JANUMET": 2.757949605982369, "JANUVIA": 1.998747649088209, "JARDIANCE": 1.126646102149591, "KAFTRIO": 1.2158659026569774, "KALETRA": 2.577004540108397, "KIVEXA": 2.9624545263051005, "LEFLUNOMIDE": 5.070102868504719, "LOPINAVIR": 1.7334674949469149, "LURASIDONE": 1.9969566253463635, "LYNPARZA": 1.7394645724937017, "MANNITOL": 3.216957661056536, "MAVENCLAD": 1.4026246297541167, "METHOTREXATE": 1.2752793343219542, "MIMPARA": 9.903060537196342, "MULTAQ": 2.347478014591894, "MYCOPHENOLATE": 1.9121425310648408, "OCRELIZUMAB": 1.591290771119256, "OFEV": 5.779469064507282, "OLYSIO": 1.246374365122734, "ONGLYZA": 1.3152994582674873, "OPSUMIT": 1.207574306358297, "ORKAMBI": 1.93843450746498, "OZEMPIC": 4.552604323420191, "PACLITAXEL": 2.156574212832773, "PEMETREXED": 1.5047452347183234, "PIRFENIDONE": 3.178118821584988, "POSACONAZOLE": 1.742108546061668, "RAPAMUNE": 1.7124795738916463, "REVATIO": 1.052674001541912, "REVLIMID": 1.081927373874058, "RILUZOLE": 4.771925269578914, "RINVOQ": 1.981601497942557, "RISPERIDONE": 1.2687938549413793, "RITUXIMAB": 1.366357482177958, "ROTATEQ": 1.0110499376449165, "RUBRACA": 1.7797865395509884, "RUCONEST": 1.6468714496602217, "RYBELSUS": 5.848672965309435, "SAXENDA": 1.5381988709430914, "SORAFENIB": 1.156534882027003, "SPIRONOLACTONE": 1.0997003010628563, "SPRYCEL": 1.810383983295636, "SUTENT": 1.4871944210279413, "TECFIDERA": 2.9706934730808774, "TEGAFUR": 3.3255390937417397, "TERIPARATIDE": 1.5177988682035763, "TOVIAZ": 1.7286051911086135, "TRIUMEQ": 1.8840399441549185, "TRULICITY": 4.785879419259922, "VELTASSA": 1.5831817990494557, "VICTOZA": 2.3899893909189664, "XALKORI": 1.1890000201405284, "XELJANZ": 2.2797336788872733, "XELODA": 2.898946129614268, "XYREM": 1.4411149183003835, "YERVOY": 1.0381739330358823, "ZAVESCA": 7.548389892201959}
\ No newline at end of file
+{"ABATACEPT": 3.364908280055548, "AMIKACIN": 49.65664319903518, "AMINOSALICYLIC": 3.975890909407739, "ARAVA": 1.3218395482394665, "BEDAQUILINE": 7.786492816151993, "BRIDION": 7.269229752610314, "CASPOFUNGIN": 13.223666380999967, "COMIRNATY": 0.6050007486020608, "ENBREL": 2.11146654097991, "EXJADE": 2.751221742200725, "GARDASIL": 1.0243302024644108, "KEPPRA": 1.1820289713266536, "NOT": 12.530174202446329, "PEGASYS": 1.9800667811338304, "PEGINTERFERON": 9.773174139675096, "PEGINTRON": 2.7178549290624803, "SHINGRIX": 1.7156898850687077, "SIMPONI": 1.5069169842271897, "SPIKEVAX": 0.8975601687869855, "TOBRAMYCIN": 46.524488193918536, "TOZINAMERAN": 1.5735373781591888, "VAXZEVRIA": 0.3403008932313517, "VIAGRA": 4.574890635439518, "ZOSTAVAX": 24.90664921616497, "null": 0.9238806092298112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3383.json
index 989f95d48e2..0a333d07d66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3383.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3383.json
@@ -1 +1 @@
-{"APTIVUS": 4701.065232172242, "null": 2.1389058749145065}
\ No newline at end of file
+{"null": 0.8839493325626656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3384.json
index 8a6904ad402..86682c69afe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3384.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3384.json
@@ -1 +1 @@
-{"BLINCYTO": 549.966731309946, "CLOPIDOGREL": 9.094701559184733, "IBUPROFEN": 16.06182916324016, "null": 1.5812671635834383}
\ No newline at end of file
+{"ACETYLSALICYLIC": 1249.3627683550633, "ARAVA": 11.2551172366589, "COMIRNATY": 0.7254076769442789, "SPIKEVAX": 0.5387890223266854, "TOZINAMERAN": 1.4766631704616398, "VAXZEVRIA": 0.3461661410646872, "VIAGRA": 18.932642715529937, "null": 0.7004544106832378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3385.json
index 1097355e550..74d96f3c8e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3385.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3385.json
@@ -1 +1 @@
-{"null": 1.0603933974467676}
\ No newline at end of file
+{"CHAMPIX": 0.7314970278704915, "COMIRNATY": 1.3867229648979948, "COSENTYX": 0.7767757206492615, "EXJADE": 2.863145960057348, "GARDASIL": 0.4844287824070723, "HUMALOG": 2.9728908494906188, "JARDIANCE": 1.0685186758884055, "LANTUS": 1.5701182182526834, "MIDAZOLAM": 3.323954825421761, "MODERNA": 2.5264058805001435, "PEGASYS": 2.271282694386239, "PEGINTRON": 1.190429502108967, "REVATIO": 4.510996090418813, "SHINGRIX": 2.585226494230535, "SIMPONI": 1.059376608978174, "SPIKEVAX": 1.9375020304733128, "STELARA": 0.9200163574221242, "SUTENT": 0.3145121927277615, "TOZINAMERAN": 3.695659404999448, "VAXZEVRIA": 0.6021448696129078, "VIAGRA": 12.43748808646233, "XELJANZ": 1.2409721357798644, "ZOSTAVAX": 3.988126348769426, "null": 0.637422642891452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3386.json
index 7b452ceb26d..2ca915296a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3386.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3386.json
@@ -1 +1 @@
-{"ADEMPAS": 1.1056657775920218, "ADVATE": 1.5795452091837825, "ALISKIREN": 1.5644285982919206, "AMBRISENTAN": 1.1163910333927871, "AMIKACIN": 1.9251311132092208, "APIXABAN": 1.5422982043289737, "ARIXTRA": 4.525780544756375, "AVASTIN": 1.3346650851031494, "BEVACIZUMAB": 2.088693443626908, "BIVALIRUDIN": 11.818976646273246, "BLINCYTO": 2.7820656683259557, "BLINDED": 7.374994973018202, "BOSENTAN": 1.5735947911464896, "BRAFTOVI": 1.2921825568584118, "BRILIQUE": 12.684666894444588, "BUMETANIDE": 5.442925584424548, "BUSULFAN": 1.006038419151813, "CANAKINUMAB": 5.74002712676863, "CAPECITABINE": 1.017527465791079, "CEFUROXIME": 4.852642484573176, "CELECOXIB": 1.6116690960676032, "CELLCEPT": 1.2990457982311274, "CLADRIBINE": 1.099604424563973, "CLOPIDOGREL": 21.18256151102046, "DABIGATRAN": 21.000419612953703, "DACLATASVIR": 1.2078436752603272, "DEFITELIO": 23.35457233548314, "DOXORUBICIN": 1.1611554173959473, "DUOPLAVIN": 10.826895796243075, "EFIENT": 16.383053344857686, "ELIQUIS": 18.527345941885574, "EMTRIVA": 1.877974283135318, "ENOXAPARIN": 11.994452504279923, "EPOETIN": 1.3759437242856156, "EXJADE": 2.5713179417725045, "EXVIERA": 1.4161779578300364, "HARVONI": 1.4771692539820256, "HEMLIBRA": 6.294670412179276, "IBUPROFEN": 2.502131960766863, "INTEGRILIN": 7.035055564647983, "IRESSA": 1.282533049628671, "IRON": 1.08388036901275, "ISCOVER": 39.32767285319074, "JAKAVI": 2.3123365036343437, "JEVTANA": 2.072903768233016, "LENVIMA": 1.5795273845575752, "LIXIANA": 10.461450232395146, "LUTATHERA": 1.1966910733912446, "MIRCERA": 2.045537022447713, "MULTAQ": 1.0697888946073877, "NEXAVAR": 2.939306113624412, "NOT": 1.312196912784554, "NOVOSEVEN": 1.605901529821581, "NPLATE": 3.2976614403712707, "OFEV": 1.3824856108477834, "OLYSIO": 1.1284268017310486, "OPSUMIT": 1.4231775553732655, "OXYBUTYNIN": 1.1757466511642498, "PAZOPANIB": 1.0468498305058127, "PLAVIX": 58.14072678754583, "PRADAXA": 19.626319511374497, "PRASUGREL": 19.494778613008457, "PRAXBIND": 16.882217703784267, "REMDESIVIR": 1.1529107507910257, "REVATIO": 1.8936765403460012, "REVLIMID": 1.6881012675350828, "RIVAROXABAN": 6.93947588683711, "RUXOLITINIB": 1.545276948166519, "SOLIRIS": 1.144521024272502, "SORAFENIB": 1.9173786546749416, "SOVALDI": 1.6548360617742135, "SPRYCEL": 3.3973685983653867, "STIVARGA": 1.3671360726395627, "SUTENT": 1.798741434844621, "THALIDOMIDE": 1.2186475970587776, "TICAGRELOR": 26.04518349788933, "TORISEL": 1.1372342438373555, "TRACLEER": 1.95644690986882, "VOTRIENT": 1.1524444351573435, "XARELTO": 35.33280087468717, "XELODA": 1.090286975460449, "YERVOY": 1.2986525161359357, "YESCARTA": 1.0745830389530664, "null": 1.0666229454045648}
\ No newline at end of file
+{"ABACAVIR": 0.3478482399222566, "ABILIFY": 0.2006909972100042, "ABRAXANE": 0.9424966304965788, "ACTOS": 0.2133181443360613, "ACTRAPID": 0.6780538822669375, "ADALIMUMAB": 0.0073281848913412, "ADCETRIS": 0.4924624929541688, "ADCIRCA": 1.206315583855787, "ADEMPAS": 0.4606792406354284, "ADVAGRAF": 2.7618291215284216, "ADVATE": 1.1984156532733252, "AFINITOR": 3.151912110882329, "AIMOVIG": 0.030034704360667, "ALEMTUZUMAB": 0.1759205550095239, "ALIMTA": 2.133419272886312, "ALL": 0.6462034613594855, "ALPELISIB": 0.4405978782680665, "AMBRISENTAN": 1.3507673599351673, "AMIKACIN": 0.3293660798254267, "AMINOSALICYLIC": 0.3079468592150819, "ANAKINRA": 0.084828408265402, "ANGIOX": 2.177920083353408, "ANIDULAFUNGIN": 0.6979881391425461, "ANORO": 0.4521992971047941, "APIDRA": 0.3457030098565422, "APIXABAN": 0.1101156844077651, "APROVEL": 0.1484039468540033, "ARANESP": 8.112188628039329, "ARAVA": 0.0260283315111054, "ARIPIPRAZOLE": 0.3753166405441578, "ARIXTRA": 0.3543278197364179, "ARZERRA": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3387.json
index 008417c53cc..b8736683792 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3387.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3387.json
@@ -1 +1 @@
-{"null": 1.4866183179796872}
\ No newline at end of file
+{"ADALIMUMAB": 2.155852894417445, "ARAVA": 1.0417320843284386, "COMBIVIR": 20.711876675652128, "ENFUVIRTIDE": 478.73827759828566, "null": 2.015287736931408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3388.json
index 45b389ef63b..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3388.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3388.json
@@ -1 +1 @@
-{"LEVETIRACETAM": 14.053173956490076, "OLANZAPINE": 10.899062263753558, "null": 1.80817282307762}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3389.json
index 9ba5d2a6381..f342bf44d00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3389.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3389.json
@@ -1 +1 @@
-{"AIMOVIG": 2.0943316134140035, "BENLYSTA": 4.824353772710448, "BUSULFAN": 23.412423763860627, "CICLOSPORIN": 2.0550829578357783, "CIMZIA": 2.041999074780153, "COSENTYX": 3.09794455258931, "ELIQUIS": 1.03990974554988, "ENTYVIO": 4.301088094830861, "EXJADE": 1.7769657248534847, "FORSTEO": 1.692397955016376, "HUMALOG": 1.264813986953805, "HUMIRA": 4.693973515550377, "JANUMET": 1.9233229914352497, "JARDIANCE": 2.809379860524811, "NAGLAZYME": 22.614233901482383, "PEGASYS": 1.809792729366135, "PEGINTRON": 3.210533593246148, "SIMPONI": 3.47225670197126, "SOLIRIS": 3.210488869710817, "SOMATROPIN": 38.17183352978912, "SPINRAZA": 18.743216724599115, "SPRYCEL": 3.700380359652028, "STELARA": 3.727768642059204, "SUBOXONE": 1.918590668552486, "SUTENT": 1.00360598030352, "TRACLEER": 2.727520721167108, "VOTRIENT": 1.795028406889002, "XELJANZ": 3.57286524457515}
\ No newline at end of file
+{"null": 1.3453712080961109}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/339.json
index 37ea311b38c..1aee12a618c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/339.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/339.json
@@ -1 +1 @@
-{"KUVAN": 2041.1466107797487, "MIDAZOLAM": 115.61316650366412}
\ No newline at end of file
+{"BUDESONIDE": 19.057600962222093, "FLUTICASONE": 283.2160330588304, "HYDROCORTISONE": 56.34668195666265, "KALETRA": 10.210348998605026, "LOPINAVIR": 157.6351853153346, "RITONAVIR": 187.3555018347998, "STRIBILD": 6.897087185349649, "null": 2.2265668864084462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3390.json
index 1b554542f46..f4ed5ca7446 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3390.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3390.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.2050265741228066, "BUDESONIDE": 2.21165704363644, "CIMZIA": 2.249389789070774, "COSENTYX": 4.1816844459102445, "CYTARABINE": 8.352669647091659, "DEXAMETHASONE": 5.315448401256777, "ENBREL": 3.056925040868808, "ENTYVIO": 19.3713413801621, "FORSTEO": 2.985178015294516, "HUMIRA": 7.916630964978486, "IBUPROFEN": 3.836057073915208, "KEYTRUDA": 1.2878987292971915, "ROACTEMRA": 4.279092082189036, "SIMPONI": 2.1777499055544225, "STELARA": 3.315620923347393, "SUTENT": 1.0785201618077207, "XELJANZ": 1.254487447602708, "null": 1.0018342987333626}
\ No newline at end of file
+{"CICLOSPORIN": 32.562597837388644, "JARDIANCE": 18.3068073580257, "null": 1.01074925253923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3391.json
index 543de536270..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3391.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3391.json
@@ -1 +1 @@
-{"SUTENT": 3.357586225954541, "null": 1.3610878716984165}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3392.json
index 1815c4ed4c6..a8a542419ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3392.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3392.json
@@ -1 +1 @@
-{"null": 1.6691528772302124}
\ No newline at end of file
+{"null": 1.1487346130258136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3393.json
index 8cf2aec55a9..70b227a9a8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3393.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3393.json
@@ -1 +1 @@
-{"APTIVUS": 1714.2496582015333, "null": 2.0414027323249155}
\ No newline at end of file
+{"null": 1.839196798798022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3394.json
index 582c23f523a..37f565f86fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3394.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3394.json
@@ -1 +1 @@
-{"AIMOVIG": 7.850400456265434, "AUBAGIO": 1.8512076838690752, "BEVACIZUMAB": 3.715715134583625, "BUPRENORPHINE": 3.94302250719799, "CELLCEPT": 2.145583538463665, "CHAMPIX": 1.4023199522991805, "COSENTYX": 1.814597779633298, "ENTRESTO": 1.9063607270866183, "GARDASIL": 2.099541604819133, "IBRANCE": 1.1381492152618544, "LEVOFLOXACIN": 4.399158594160427, "SUTENT": 1.1472418215748537, "TRACLEER": 2.457210643549166, "ZYPREXA": 1.5766196217330264, "null": 1.6403419477922287}
\ No newline at end of file
+{"null": 0.8145643285262828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3395.json
index f4db1139354..59c640e0297 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3395.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3395.json
@@ -1 +1 @@
-{"ENTYVIO": 46.57399219960523, "HUMIRA": 67.50825723639898}
\ No newline at end of file
+{"null": 4.119574753208079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3396.json
index 3b2a5ca3242..1a3d70dcc67 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3396.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3396.json
@@ -1 +1 @@
-{"CICLOSPORIN": 9.960250042807528, "null": 1.506167433907904}
\ No newline at end of file
+{"CYMBALTA": 177.51117891722757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3397.json
index e8728a8fac0..7f87e3507a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3397.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3397.json
@@ -1 +1 @@
-{"null": 1.724603477394154}
\ No newline at end of file
+{"null": 2.429837098764564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3398.json
index e681baf281d..8f855c97d0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3398.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3398.json
@@ -1 +1 @@
-{"ALIMTA": 7.540149650996057, "ASPARAGINASE": 6.965564877225422, "AVASTIN": 10.786525829714742, "BEVACIZUMAB": 8.304550847446531, "CICLOSPORIN": 1.407227339145385, "DEXAMETHASONE": 4.014330847842955, "DOCETAXEL": 5.149910107105815, "INCIVO": 11.24826156720184, "KEYTRUDA": 1.2752358435344744, "OLANZAPINE": 2.9361393491811647, "ROTATEQ": 14.624890838600027, "SAXENDA": 5.953425285382934, "SUTENT": 1.4586718291776344, "null": 1.937060499674576}
\ No newline at end of file
+{"ARIPIPRAZOLE": 1.2500711831539115, "ATRIPLA": 10.947133483936566, "AVANDIA": 1.9853148465509751, "CHAMPIX": 0.4724557740401247, "COMIRNATY": 0.3169638244070029, "COMTAN": 5.06970309985907, "COSENTYX": 0.6357696561584788, "CYMBALTA": 0.6761255235355974, "ELIQUIS": 0.4715585111613726, "ENBREL": 0.7282871322097716, "ENTRESTO": 0.7189399901180262, "ESBRIET": 1.4165828046185391, "FASENRA": 3.426422038768053, "FENTANYL": 1.2401350169639591, "GARDASIL": 2.321012922317694, "HUMALOG": 0.7207425174815386, "INFLIXIMAB": 54.36259970695628, "JAKAVI": 1.8787186134946805, "KEPPRA": 1.5834560832943552, "KEYTRUDA": 1.7754287323976958, "LATUDA": 3.881731015195834, "MEPOLIZUMAB": 12.547635796866675, "NEXAVAR": 0.6758028285915848, "NUCALA": 4.2231260259014585, "OLANZAPINE": 1.6841072817944702, "OMALIZUMAB": 1.6206216810589282, "OPSUMIT": 1.8140144361508477, "PEGASYS": 0.5956152549724372, "PEGINTRON": 0.6950079989057757, "ROTATEQ": 3.141866625260112, "SPIKEVAX": 0.3120100395013971, "STRIBILD": 8.72562595648275, "TOZINAMERAN": 0.2760908880480026, "TRACLEER": 1.188877939554129, "TRUVADA": 6.27635512038181, "VAXZEVRIA": 0.1347292331133123, "VIREAD": 6.932719736180123, "XELJANZ": 0.4512853192695195, "XOLAIR": 0.9666482290141922, "XTANDI": 1.3159658180591405, "ZOSTAVAX": 0.919178737208487, "ZYPREXA": 1.5835152710238969, "null": 0.8758500802256368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3399.json
index aaefc242cc8..e0e0080e2f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3399.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3399.json
@@ -1 +1 @@
-{"AIMOVIG": 5.593811570637025, "MEPOLIZUMAB": 15.247776576126975, "PANTOPRAZOLE": 16.61317386606097, "null": 1.1443967052300812}
\ No newline at end of file
+{"ABACAVIR": 0.2745904512540848, "ABASAGLAR": 0.8388720246752697, "ABATACEPT": 0.8008954974412691, "ABEMACICLIB": 1.4466655978376213, "ABILIFY": 0.4720563565585371, "ABRAXANE": 1.6140545470181196, "ACETYLSALICYLIC": 7.199406773795759, "ACTOS": 0.8854189539840158, "ACTRAPID": 0.2439346762760371, "ADALIMUMAB": 1.7897060154584457, "ADCETRIS": 1.1198904085172816, "ADCIRCA": 0.890376440026915, "ADEMPAS": 1.018896110420103, "ADENURIC": 0.8127520993898113, "AERIUS": 0.1566907879458519, "AFINITOR": 2.292187610581883, "AFLIBERCEPT": 1.790212196156862, "AIMOVIG": 0.6944471402913113, "ALDARA": 1.1864645663227205, "ALEMTUZUMAB": 0.5006519276504404, "ALIMTA": 2.4469302198966942, "ALISKIREN": 0.1733107534785166, "ALPELISIB": 3.3957151388778506, "AMBRISENTAN": 1.4171942961991115, "AMIKACIN": 0.6595472448793502, "AMINOSALICYLIC": 0.9718089660310936, "ANORO": 0.1429346559938127, "ANTIBIOTICS": 0.7916639503961425, "APIDRA": 0.5718322724152965, "APIXABAN": 0.0904037661862531, "APREMILAST": 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0.4624452875484023, "SIMPONI": 0.2564939800798113, "SIRTURO": 1.7304039040765753, "SOFOSBUVIR": 0.9506019370495524, "SOLIRIS": 0.4749495470814657, "SOMATROPIN": 0.2878502436943177, "SORAFENIB": 1.717612367784255, "SOTORASIB": 1.2046568960866608, "SOVALDI": 1.3335322521409918, "SPIKEVAX": 0.5612388647908981, "SPINRAZA": 0.2093876701794802, "SPIRONOLACTONE": 1.470273783540918, "SPRYCEL": 1.1562800815916032, "STALEVO": 1.0109056536005223, "STELARA": 0.4542051598774991, "STIRIPENTOL": 15.524314913312612, "STIVARGA": 3.9401919381728985, "STOCRIN": 1.508357461992276, "STRIBILD": 0.0518104308419803, "SUBOXONE": 0.8000502709001865, "SUNITINIB": 2.062663679196262, "SUTENT": 4.0084959081960765, "SYNAGIS": 0.6576369138972701, "TACROLIMUS": 0.3880679147175341, "TAFINLAR": 0.9023264890351806, "TAGRISSO": 3.3204262462477563, "TAMIFLU": 0.8902694719321746, "TARCEVA": 1.5695490169906503, "TASIGNA": 0.7234002874942608, "TAXOTERE": 1.6518541583734836, "TEDUGLUTIDE": 1.6720787368121073, "TEGAFUR": 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"VELMETIA": 1.0800205688559474, "VELTASSA": 0.709941280909987, "VEMLIDY": 0.8695931493507492, "VEMURAFENIB": 1.0133065980058151, "VENCLYXTO": 0.3146308963715769, "VENETOCLAX": 0.2384229437979279, "VFEND": 0.8143956328389002, "VIAGRA": 0.1123268190449712, "VICTOZA": 2.810615314216759, "VILDAGLIPTIN": 1.0453057630725002, "VIMPAT": 0.5764847789963345, "VIRAMUNE": 0.3289187547280341, "VIREAD": 0.2763515720538588, "VORICONAZOLE": 0.4195302448043034, "VOTRIENT": 3.90322581556495, "XALKORI": 2.234628177644302, "XARELTO": 0.6097426548811926, "XELJANZ": 0.4793307949665483, "XELODA": 3.0375208785619394, "XGEVA": 1.6351852108169087, "XOFIGO": 2.65919295287684, "XOLAIR": 0.2370707218265615, "XTANDI": 5.03868802931042, "XYREM": 0.9938295605387928, "YERVOY": 1.4835107598108128, "YESCARTA": 0.8778768916181404, "YONDELIS": 1.035030062406776, "ZEJULA": 1.499674866864874, "ZELBORAF": 2.971989527805782, "ZEPATIER": 1.422820873826382, "ZOMETA": 1.0117084276357031, "ZOSTAVAX": 0.3807595505203547, "ZYCLARA": 2.6708066364486056, "ZYPREXA": 0.5355980737541052, "null": 0.8369899941630312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/34.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/34.json
index 57107632c5f..965b1b7e007 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/34.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/34.json
@@ -1 +1 @@
-{"ACETYLSALICYLIC": 176.27066865559016, "ARAVA": 1.3861588393325033, "BUPIVACAINE": 7.009046843402321, "BYETTA": 7.326786308921675, "ELIQUIS": 1.4862313833632923, "EMPAGLIFLOZIN": 8.097988738803862, "ESBRIET": 3.4065076003331902, "FORXIGA": 2.518791676737123, "GARDASIL": 2.2635609413244744, "INVOKANA": 10.850415787038829, "JANUMET": 7.07743946226606, "JANUVIA": 3.907935796149604, "JARDIANCE": 4.801740890471533, "KEYTRUDA": 1.2041568271141012, "NEXAVAR": 2.884630197055093, "OFEV": 9.189783815760324, "PEGINTRON": 1.547329567613987, "SIMPONI": 2.036153686104346, "STELARA": 1.3177608791759534, "XARELTO": 8.345556497234348, "ZOSTAVAX": 2.593827767860415, "null": 1.1557669805036228}
\ No newline at end of file
+{"null": 0.8542188227567449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/340.json
index fc87995db12..1e02e623a53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/340.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/340.json
@@ -1 +1 @@
-{"HEPSERA": 731.2622665216284}
\ No newline at end of file
+{"null": 0.6378939197264512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3400.json
index 71f5830f3eb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3400.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3400.json
@@ -1 +1 @@
-{"HUMIRA": 6.804568812232067, "KEYTRUDA": 4.802839406130677, "SUTENT": 3.1279131691249797, "ZYPREXA": 3.0268398602898263, "null": 1.507227470279817}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3401.json
index c574ea3e5a8..5f0bf8b1a46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3401.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3401.json
@@ -1 +1 @@
-{"ACETYLSALICYLIC": 50.74511261053413, "ADCIRCA": 4.7052299480691335, "AIMOVIG": 1.4675917327926726, "BRAFTOVI": 1.6147600882472282, "BRINTELLIX": 2.7978279130333235, "COMIRNATY": 1.4314503579904685, "COSENTYX": 1.7420717626354507, "COVID19": 1.2946624389449963, "ENTYVIO": 2.313433448755051, "FAMPYRA": 2.088580169190032, "FORSTEO": 1.116181254616537, "LIXIANA": 1.9593535279852288, "OFEV": 2.742896542182305, "SAXENDA": 1.9034547451489636, "SPIKEVAX": 1.244199845277584, "TOZINAMERAN": 1.1873892848530234, "TRULICITY": 2.829708585882691, "VAXZEVRIA": 1.1671105464305127, "VICTOZA": 2.1806319908026577, "XELJANZ": 1.5428098112476782, "null": 1.1440758422497128}
\ No newline at end of file
+{"ARIPIPRAZOLE": 50.27907563984278, "null": 1.877060246025912}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3402.json
index 1d4179b64a5..599df262c9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3402.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3402.json
@@ -1 +1 @@
-{"ALIMTA": 4.130067607171318, "ANAKINRA": 13.037557209225357, "ASPARAGINASE": 4.69816200492505, "AVASTIN": 94.09625524929132, "BEVACIZUMAB": 21.148462020263786, "CABOMETYX": 10.47929390275256, "CELLCEPT": 2.548105606744804, "CICLOSPORIN": 1.075533693674835, "DEXAMETHASONE": 2.213774126933728, "INLYTA": 8.656871112969979, "IRESSA": 5.0569163625333, "KEYTRUDA": 10.0352383419167, "LENVIMA": 40.12790119771768, "NEXAVAR": 10.247663107593302, "OFEV": 4.392510452123849, "OPDIVO": 4.875137917493226, "RINVOQ": 25.263895824690486, "ROACTEMRA": 8.988673882237274, "STIVARGA": 30.192403927791126, "SUTENT": 5.372064203411801, "VECTIBIX": 16.415169105565433, "VOTRIENT": 7.039805241374208, "XELJANZ": 4.026268233561218}
\ No newline at end of file
+{"ABACAVIR": 21.23767603914714, "AIMOVIG": 1.207556168625796, "ARAVA": 0.2548896823882677, "BENLYSTA": 8.93098225373147, "CICLOSPORIN": 0.9226351290856264, "COMIRNATY": 0.4671303777842311, "COSENTYX": 5.5274281030321015, "ENBREL": 1.6292694376629546, "FULVESTRANT": 20.95656414350695, "GARDASIL": 2.943925815988416, "HUMALOG": 0.740579115212432, "IBRANCE": 49.92635885832409, "INLYTA": 2.0287432523324465, "KISQALI": 22.14361000558108, "METHOTREXATE": 1.1980940643952358, "NUCALA": 2.0192089599458, "PANTOPRAZOLE": 9.79581865466779, "PEGINTRON": 3.022503091221117, "PLEGRIDY": 3.8680999406553305, "SHINGRIX": 0.9211657664175243, "SIMPONI": 7.971752282537459, "SPIKEVAX": 0.2819924149383368, "STELARA": 2.5300009352228536, "SUTENT": 7.924656135948564, "TOZINAMERAN": 0.2541547885731939, "TREMFYA": 4.470860084643962, "VAXZEVRIA": 0.0562919010731364, "XELJANZ": 10.188951469735931, "null": 0.3835088915177574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3403.json
index 179898e4aa6..45953743f0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3403.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3403.json
@@ -1 +1 @@
-{"ELIQUIS": 18.791516240245475}
\ No newline at end of file
+{"APIDRA": 86.54995632641395, "null": 0.6279266014165759}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3404.json
index 2a432aa8d0c..c23a7695bca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3404.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3404.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 10.278543701339492, "ELIQUIS": 16.839176470809043, "PLAVIX": 18.225551095337597, "XARELTO": 50.88177702095466}
\ No newline at end of file
+{"ABILIFY": 3.9443414333923887, "ANTIBIOTICS": 41.17722194602349, "AUBAGIO": 25.22844244537752, "CHAMPIX": 10.753986066006012, "COMIRNATY": 0.1719457957689902, "CYMBALTA": 2.879914488741464, "HYDROCORTISONE": 20.65144545125152, "KEPPRA": 1.46609069107637, "OLANZAPINE": 3.4041321661892483, "SPIKEVAX": 0.1291403985448841, "TOZINAMERAN": 0.3539359568706952, "VAXZEVRIA": 0.1199845881000391, "XTANDI": 3.500845114834425, "ZYPREXA": 2.7069383970640644, "null": 1.92436842743977}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3405.json
index e9130e7d96e..4468ff4444f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3405.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3405.json
@@ -1 +1 @@
-{"null": 1.3445297455178007}
\ No newline at end of file
+{"COMIRNATY": 0.606477812934982, "CYMBALTA": 4.580825816906108, "null": 0.7540083193257429}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3406.json
index 6c82a22fe34..67d229fbaf6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3406.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3406.json
@@ -1 +1 @@
-{"ASPARAGINASE": 561.9550542438122}
\ No newline at end of file
+{"ARANESP": 1.7093949571171354, "AUBAGIO": 2.847924794463969, "BUPIVACAINE": 8.95210979949214, "CABOMETYX": 3.3643969707258976, "COMIRNATY": 0.0891544239526733, "CYMBALTA": 1.6534567146987522, "ELIQUIS": 1.8621243718532223, "FASLODEX": 2.1597540566125097, "HUMALOG": 1.0151201368638545, "IBRANCE": 1.3818944965548825, "JANUMET": 6.141557006812847, "JANUVIA": 3.0408725616524674, "JARDIANCE": 1.4595335582915527, "KEPPRA": 1.3427937948098931, "KEYTRUDA": 1.293375283044274, "LANTUS": 2.2906359323148293, "OCEAN": 276.19978532385227, "OLANZAPINE": 2.83301489385638, "OPTIMARK": 4.025311048765015, "OXYBUTYNIN": 15.403207351665197, "PLAVIX": 2.065967387394839, "SIMPONI": 1.108557868906181, "SPIKEVAX": 0.0964555428926005, "SUTENT": 6.584648758911328, "VAXZEVRIA": 0.0462569338198587, "XELJANZ": 1.5894677842104432, "XTANDI": 1.319131419098881, "ZOSTAVAX": 0.9936694480287864, "ZYPREXA": 3.724063753471079, "null": 1.2083778650864565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3407.json
index 1e6eaede568..80ee148ee49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3407.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3407.json
@@ -1 +1 @@
-{"AIMOVIG": 2.1280137911869565, "CLOPIDOGREL": 1.285268470770674, "CYMBALTA": 1.8308881378618256, "EXJADE": 2.2892227298083045, "IBUPROFEN": 5.901962992254547, "JANUMET": 2.7459735770343414, "LYRICA": 2.822372060384305, "OFEV": 4.484790637477156, "OLANZAPINE": 5.160806530250731, "ROTATEQ": 18.05493430872045, "SUTENT": 1.1461668485489762, "TRULICITY": 4.279817904951046, "ZYPREXA": 1.9673230189740047, "null": 2.406696308992664}
\ No newline at end of file
+{"null": 1.3795944005902652}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3408.json
index 151d525a8f5..ec355394ad5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3408.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3408.json
@@ -1 +1 @@
-{"LIRAGLUTIDE": 194.6685964208562, "TEDUGLUTIDE": 831.550395288055, "null": 1.3397980106476777}
\ No newline at end of file
+{"ABATACEPT": 0.0826035464699559, "ABILIFY": 0.4036738623052781, "ACTOS": 0.6780290639503825, "ADALIMUMAB": 0.6962396261005315, "AFINITOR": 0.4332477168702472, "AIMOVIG": 0.1364814911740066, "ALEMTUZUMAB": 0.2604480920012698, "ALIMTA": 1.4415272176905771, "AMINOSALICYLIC": 1.1028847619798594, "ANAKINRA": 7.391566688741732, "APIXABAN": 1.9696302527246223, "ARANESP": 1.2395031814878066, "ARAVA": 0.0827070663078309, "ARIXTRA": 2.794004113644586, "ASPARAGINASE": 1.7167700977949394, "ATAZANAVIR": 0.355416835304832, "AUBAGIO": 0.1503275312807885, "AVANDAMET": 0.3807060254115768, "AVANDIA": 0.4577687238244068, "AVASTIN": 3.4354627037165035, "AZATHIOPRINE": 0.5451077688647447, "BEDAQUILINE": 0.7226542245747577, "BENLYSTA": 0.2083162575785533, "BETAFERON": 0.4108033170111294, "BEVACIZUMAB": 2.5383186231088914, "BIKTARVY": 0.2251739263025018, "BORTEZOMIB": 1.7278903320365704, "BUDESONIDE": 0.5912413707261728, "BUSULFAN": 0.2031219979218103, "BYDUREON": 0.7711759230240818, "BYETTA": 1.824953149335576, "CABOMETYX": 1.0843511326582989, "CAELYX": 0.4240856712708187, "CANAGLIFLOZIN": 3.871678560725496, "CAPECITABINE": 0.6895075216417097, "CARFILZOMIB": 2.203997307424602, "CELECOXIB": 1.2253768784074364, "CELLCEPT": 0.65923005300058, "CHAMPIX": 0.2582899492366073, "CICLOSPORIN": 0.1978218099927083, "CIMZIA": 0.392245936996955, "CINRYZE": 1.8961144281797415, "CLOPIDOGREL": 0.3663111869606096, "COMBIVIR": 0.3732691069761629, "COMIRNATY": 1.0992922132358982, "COSENTYX": 0.437085756709849, "CRIXIVAN": 0.684324046052146, "CUBICIN": 0.5629226742158538, "CYMBALTA": 0.098706265746062, "CYTARABINE": 0.5126929018731223, "DABIGATRAN": 8.230426053691161, "DARATUMUMAB": 2.0410990548424874, "DARZALEX": 0.7785805830597743, "DEXAMETHASONE": 2.0609349777334045, "DOCETAXEL": 0.6868981566236136, "DOXORUBICIN": 1.805410796518077, "EBIXA": 3.4092784052383385, "ELIQUIS": 6.08721624469232, "ENBREL": 0.3040432556302922, "ENOXAPARIN": 5.706357594558674, "ENTRESTO": 0.2433901705285442, 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"INSULIN": 0.1646265713369693, "INVOKANA": 0.8125505499676475, "IRESSA": 0.7411552690704867, "IRINOTECAN": 0.7108884917949809, "JAKAVI": 0.3917306211867839, "JANUMET": 1.077982233106434, "JANUVIA": 1.000530005429645, "JARDIANCE": 0.2282726556292035, "KALETRA": 0.4370413191114579, "KEPPRA": 0.1436396497131662, "KEYTRUDA": 0.6789603534807978, "KIOVIG": 1.249160443653147, "KYPROLIS": 2.505526223715434, "LANTUS": 0.1016943063572962, "LEMTRADA": 0.4583522705216454, "LENVIMA": 0.5123302547867167, "LEVETIRACETAM": 0.2331168332121755, "LEVOFLOXACIN": 0.1890848731867592, "LIXIANA": 1.4912842982850625, "LONSURF": 0.3802401009309289, "LYNPARZA": 0.8041846605300385, "LYRICA": 0.1382861664736501, "MABTHERA": 0.8431358220738122, "MEKINIST": 0.7984119804295944, "MELATONIN": 0.8341630477776626, "MEPOLIZUMAB": 0.2186999665986096, "METHOTREXATE": 0.5598130946165312, "MIDAZOLAM": 0.3077845703721311, "MODERNA": 0.907448786595296, "MYCOPHENOLATE": 0.3598625707554033, "NEULASTA": 0.2773680369393775, "NEXAVAR": 0.1986906075495862, "NOVOSEVEN": 20.65426123238788, "NPLATE": 6.6693390811726845, "NUCALA": 0.1101347408044805, "OCRELIZUMAB": 0.2981121033272956, "OFEV": 0.6329859446455076, "OLANZAPINE": 1.286502541836239, "OMALIZUMAB": 0.1998770947475958, "ONCASPAR": 0.912633254948314, "OPDIVO": 0.2511426799549114, "OPSUMIT": 0.2527012281114384, "OPTIMARK": 0.3032247083221958, "OSIMERTINIB": 3.057609333367075, "PEGASYS": 1.2240280427723111, "PEGINTERFERON": 0.3646965403104015, "PEGINTRON": 0.8018239259300629, "PEMBROLIZUMAB": 0.2302216260576091, "PEMETREXED": 0.551529858508036, "PLAVIX": 1.1566421873884294, "PRADAXA": 1.0885077056593806, "PREGABALIN": 0.6125237156562168, "PRIVIGEN": 1.550138993747321, "PROTELOS": 18.976521298233443, "RAPAMUNE": 2.811605695810575, "REMICADE": 0.9137354492498376, "REVATIO": 0.6687081376995209, "REVLIMID": 2.898067591665274, "RIBAVIRIN": 0.2044917084517109, "RINVOQ": 4.615440868449578, "RITUXIMAB": 0.7221184492584642, "RIVAROXABAN": 4.323992491451202, "ROACTEMRA": 1.1475218382568515, "RUBRACA": 0.3803256112248823, "SAXENDA": 0.320293801473369, "SHINGRIX": 0.1422830398518641, "SIMPONI": 0.8037931900219587, "SOLIRIS": 1.2410094817921242, "SPIKEVAX": 0.8240099076891615, "SPINRAZA": 0.3436397033016945, "SPIRONOLACTONE": 0.8562363895293943, "STELARA": 0.9562888332634524, "STIVARGA": 0.159216746845146, "SUBOXONE": 0.2127542682431895, "SUTENT": 0.5287978328394156, "TAGRISSO": 2.185114127131098, "TAMIFLU": 0.1384247681891259, "TASIGNA": 0.3809169526927476, "TEMODAL": 1.5421971082336878, "TEMOZOLOMIDE": 1.403446697722236, "TESTOSTERONE": 15.422624290547953, "THALIDOMIDE": 12.461071063351248, "TOCILIZUMAB": 1.4545386427566285, "TOFACITINIB": 5.057627676767332, "TORISEL": 0.6457374779965103, "TOZINAMERAN": 0.9205468521983804, "TRACLEER": 0.267710688548729, "TREMFYA": 0.5053214664045562, "UPADACITINIB": 3.000820755386802, "VAXZEVRIA": 1.9035577455335644, "VECTIBIX": 0.9110879748652342, "VELCADE": 2.198939800892246, "VIAGRA": 0.2431314640428205, "VICTOZA": 0.2365319802902198, "VOTRIENT": 0.6673786665969172, "XALKORI": 1.518501382813598, "XARELTO": 7.124183162691977, "XELJANZ": 1.674534086635921, "XOLAIR": 1.007110915574182, "XTANDI": 0.2952748352919903, "YERVOY": 0.6471121323499158, "YESCARTA": 0.5612733236108027, "ZOMETA": 2.0029373390952188, "ZOSTAVAX": 0.4388907283775666, "ZYPADHERA": 0.4166034745600619, "ZYPREXA": 1.5389358461898668, "null": 0.8860501808473432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3409.json
index 41722d3d5be..9e19c4e88d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3409.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3409.json
@@ -1 +1 @@
-{"TEDUGLUTIDE": 9578.639330348751, "null": 1.1422885138152594}
\ No newline at end of file
+{"ABATACEPT": 35.628808069944526, "ADALIMUMAB": 100.98854467858018, "AMINOSALICYLIC": 5.136803969116341, "APREMILAST": 8.384900697958118, "APREPITANT": 27.82150165726569, "ARAVA": 14.772536643103148, "COSENTYX": 2.4337786274623685, "MYCOPHENOLATE": 13.623505003549036, "null": 0.0143791315888844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/341.json
index 0bb0547f4b2..0e1f8b0268f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/341.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/341.json
@@ -1 +1 @@
-{"null": 2.508763467269691}
\ No newline at end of file
+{"IPILIMUMAB": 221.59627095045536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3410.json
index dc711e58b0d..ab749b8edf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3410.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3410.json
@@ -1 +1 @@
-{"null": 3.1548067533935624}
\ No newline at end of file
+{"APIXABAN": 9.16712252477114, "COMIRNATY": 0.5690390016774232, "null": 1.2540171897880594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3411.json
index 5288431b0a0..bb76005690c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3411.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3411.json
@@ -1 +1 @@
-{"GLIVEC": 339.22883004376786, "IMATINIB": 255.4870030956045, "NEXAVAR": 2.679323249244824, "NILOTINIB": 11.736393193335884, "REGORAFENIB": 37.71499409464941, "STIVARGA": 29.829892794878464, "SUTENT": 210.41239906726847, "TASIGNA": 5.131715129071721}
\ No newline at end of file
+{"ARAVA": 0.3216898410150849, "AUBAGIO": 2.621093077408025, "AZATHIOPRINE": 5.979688618091855, "BUDESONIDE": 5.341900864581514, "BUPRENORPHINE": 3.311696564130936, "COMIRNATY": 0.3339869088028032, "COSENTYX": 3.991115733602434, "ENTYVIO": 38.79022257673147, "HUMIRA": 11.732179290295871, "REMSIMA": 138.6835707644756, "SPIKEVAX": 0.2488466446593011, "STELARA": 4.978926675611783, "SUTENT": 0.7544067840494422, "TEDUGLUTIDE": 132.1431431313278, "TOZINAMERAN": 0.6489505554872013, "VAXZEVRIA": 0.1719990033349624, "XELJANZ": 9.215672312429469, "null": 1.212883882487723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3412.json
index e0942f72557..5b2fb1c653f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3412.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3412.json
@@ -1 +1 @@
-{"null": 1.1422885138152594}
\ No newline at end of file
+{"null": 2.483453351556221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3413.json
index 0a6802169ae..c6835180ec8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3413.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3413.json
@@ -1 +1 @@
-{"null": 1.0728328218393193}
\ No newline at end of file
+{"null": 3.1560025990362823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3414.json
index 959587dd0cd..37f565f86fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3414.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3414.json
@@ -1 +1 @@
-{"ABATACEPT": 2.9885736471643223, "ALIMTA": 4.251609047365809, "ARAVA": 11.267506862881076, "AVASTIN": 12.099988537573765, "BEVACIZUMAB": 20.520141478351864, "BUSULFAN": 5.18593778131551, "CABOMETYX": 5.031957878064786, "CAPECITABINE": 25.20598162039343, "CARMUSTINE": 20.46131854364733, "CELLCEPT": 2.9074255181370234, "CIMZIA": 1.5177939972005048, "CYTARABINE": 3.6019455128828524, "DOCETAXEL": 8.475191946069234, "DOXORUBICIN": 5.511553625063246, "ENBREL": 17.718969571538267, "HUMIRA": 3.413917061674866, "IRINOTECAN": 38.52815494834213, "LONSURF": 8.75236664587835, "NEXAVAR": 1.573053001135691, "PAZOPANIB": 14.277915741464014, "PEMBROLIZUMAB": 4.179261713500728, "PEMETREXED": 15.46480298601168, "SUTENT": 1.8650196581523764, "VECTIBIX": 26.317986804612485, "VOTRIENT": 3.1475600789309914}
\ No newline at end of file
+{"null": 0.8145643285262828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3415.json
index 7ee4c406293..f852392bcda 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3415.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3415.json
@@ -1 +1 @@
-{"null": 1.417404522416069}
\ No newline at end of file
+{"null": 1.7915408011315832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3416.json
index b05ffe0fa61..d54ab411caa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3416.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3416.json
@@ -1 +1 @@
-{"null": 1.2040543786333249}
\ No newline at end of file
+{"ABATACEPT": 8.230712323403948, "ADALIMUMAB": 7.511837772100804, "ANAKINRA": 93.80159978405264, "ARAVA": 4.822604890925761, "AVANDIA": 0.8628006632254659, "BEOVU": 7.856880717763529, "CIMZIA": 0.6670650081513019, "COMIRNATY": 0.0199356031529194, "CONTRAST": 78.4155383283577, "COSENTYX": 1.948265273003889, "ENBREL": 3.6300099198008544, "HUMIRA": 1.5230838260593498, "LEFLUNOMIDE": 9.367281977018592, "METHOTREXATE": 1.33737819371588, "OPTIMARK": 89.81360511996223, "PLAVIX": 3.644134102377716, "SPIKEVAX": 0.0487062134708677, "XELJANZ": 0.7891698833947608, "null": 1.6524637441600567}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3417.json
index d0efa013ffd..d6427312ee9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3417.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3417.json
@@ -1 +1 @@
-{"null": 2.154150020697041}
\ No newline at end of file
+{"null": 2.757960231456307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3418.json
index 33db17868d1..f7cf302e906 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3418.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3418.json
@@ -1 +1 @@
-{"null": 5.561076207242002}
\ No newline at end of file
+{"ESMYA": 6549.056260896661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3419.json
index 6a0dcde41db..64944e5cd2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3419.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3419.json
@@ -1 +1 @@
-{"BIKTARVY": 83.8861499345394, "CYMBALTA": 11.168888894371417, "DESCOVY": 103.9029424781775, "ELIQUIS": 6.065023838259913, "GENVOYA": 52.6857427621192, "ISENTRESS": 67.17348963327188, "JANUMET": 11.820283505952494, "JANUVIA": 14.237684525825111, "KEPPRA": 2.255196536636124, "KEYTRUDA": 1.7008749611984062, "MIMPARA": 167.58058502170368, "NOXAFIL": 16.854719342134363, "OPSUMIT": 3.6347252609911336, "REYATAZ": 25.148317704360064, "TRACLEER": 7.879626722451301}
\ No newline at end of file
+{"ATRIPLA": 42.43547536308009, "EFAVIRENZ": 48.23030616465416, "STRIBILD": 38.18806742020685, "TRUVADA": 19.51880637956595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/342.json
index 17bb8abf1eb..db615c21062 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/342.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/342.json
@@ -1 +1 @@
-{"ASPARAGINASE": 4.166168267425813, "COMBIVIR": 3.869856930423088, "CORTICOSTEROIDS": 66.1559910842339, "EXJADE": 4.95919371310263, "FENTANYL": 1.2915986167868796, "HARVONI": 4.73377396540167, "IBUPROFEN": 1.791988360210606, "KEPPRA": 3.571617882690985, "LENVIMA": 39.94253449630861, "LEVETIRACETAM": 7.289186730475309, "NEXAVAR": 12.103147509851594, "OLANZAPINE": 2.901280505008553, "OPSUMIT": 1.6299215828244236, "PEGASYS": 8.490191464134423, "PEGINTRON": 3.3838107428023614, "SODIUM": 85.14768935177429, "SOVALDI": 7.394131877404162, "STIVARGA": 9.495013922609548, "TRACLEER": 2.150567695161058, "ZYPREXA": 1.2177058349041028, "null": 2.3577383602278457}
\ No newline at end of file
+{"null": 2.855567181876348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3420.json
index 61d23a0fcad..b7d4e100ba7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3420.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3420.json
@@ -1 +1 @@
-{"BUDESONIDE": 5.328398887963538, "CLOPIDOGREL": 4.471895555675629, "ELIQUIS": 1.573087300647174, "ENTYVIO": 17.236869574978247, "PLAVIX": 10.108990527443789, "null": 1.3220097487974698}
\ No newline at end of file
+{"CLOPIDOGREL": 368.9862282496216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3421.json
index 480751d8b5c..118dcdfdb5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3421.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3421.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 29.438597113229463, "ELIQUIS": 17.486244908525382, "PLAVIX": 29.122399363631228}
\ No newline at end of file
+{"BRILIQUE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3422.json
index a12b6cccc60..76ba5060269 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3422.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3422.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 13.663792869126898, "ELIQUIS": 7.456898994754625, "PLAVIX": 63.69759577999172, "XARELTO": 113.62537844237836}
\ No newline at end of file
+{"TRULICITY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3423.json
index b2bb499d13a..6b0a9518204 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3423.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3423.json
@@ -1 +1 @@
-{"ADCIRCA": 60.44190481972753, "CYTARABINE": 10.942681602711453, "ENTYVIO": 24.172254056166583, "JANUMET": 16.068027751184317, "SUTENT": 1.743188083748588}
\ No newline at end of file
+{"ACTRAPID": 771.4370357557297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3424.json
index 3da4c84285b..60f4a646b2f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3424.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3424.json
@@ -1 +1 @@
-{"ABATACEPT": 4.377232313250558, "ACIDOPHYLUS": 188.6548206410751, "ACLIDINIUM": 10.287800028280795, "ACTOS": 2.4204642150151243, "ADALIMUMAB": 1.790442234882874, "ADCIRCA": 1.7942649693429469, "ADEMPAS": 5.202931402120904, "AERIUS": 1.250384692457892, "AIMOVIG": 7.421474488177809, "ALENDRONATE": 21.912182297773743, "AMBRISENTAN": 1.8275939333993612, "APIXABAN": 14.901966211884067, "APREMILAST": 6.037412219410965, "ARZERRA": 5.681558831972588, "AVAMYS": 8.66150726419908, "AZATHIOPRINE": 1.6258938377365642, "BONVIVA": 1.872825090020198, "BOSULIF": 2.293583928277473, "BRINTELLIX": 1.213234960232226, "BUDESONIDE": 8.674658844538305, "BUMETANIDE": 1.1825918166513238, "BYDUREON": 2.250476123253049, "BYETTA": 3.873405957214678, "CABOMETYX": 1.235800939791118, "CANAGLIFLOZIN": 29.983030457329612, "CELECOXIB": 5.990069125001586, "CELLCEPT": 3.660109447625509, "CIALIS": 2.1911670814768214, "CLOPIDOGREL": 1.234051511465256, "CYMBALTA": 1.1774103826309306, "DAXAS": 19.83139000450531, "DOXORUBICIN": 1.0627770381992707, "DULAGLUTIDE": 3.5689845901352006, "DULOXETINE": 5.4096615299870985, "ELIQUIS": 1.2803433934926358, "EPIVIR": 1.3277533245542623, "ESBRIET": 3.655058888598689, "ESOMEPRAZOLE": 2.660388133778673, "EUCREAS": 1.0716307340757458, "EVISTA": 1.7964655895962265, "FASLODEX": 1.3177617033924585, "FIRDAPSE": 1.213695260102609, "FORSTEO": 1.5969938836389348, "GARDASIL": 1.218129025391623, "GLYCOPYRRONIUM": 18.322820597305565, "HUMIRA": 1.073950948629472, "IBRANCE": 1.895797131721546, "IMATINIB": 2.3583125643022504, "INCRUSE": 1.159432954994116, "INVOKANA": 3.2746162923476883, "IRON": 3.415932269904946, "JANUMET": 5.887072291471896, "JANUVIA": 4.193857916288003, "KAFTRIO": 1.203231987407401, "KISQALI": 1.098855157247465, "KUVAN": 3.1855983746183605, "LIRAGLUTIDE": 1.8091837420145656, "LYRICA": 1.925992442301664, "MEPOLIZUMAB": 2.4684664846831663, "METFORMIN": 3.853063278370715, "MICARDIS": 1.3235624143569564, "MIMPARA": 1.291446831046822, "NUCALA": 1.6121572556885022, "OFEV": 1.0330006915024026, "ONGLYZA": 1.2047107270071145, "OPSUMIT": 1.0471125026938506, "OXYBUTYNIN": 4.8343267963461125, "PANTOPRAZOLE": 1.149900341497634, "PLAVIX": 1.5571133057407396, "RELVAR": 1.422001343127212, "REVATIO": 1.0828284833212063, "ROTATEQ": 1.715689964210641, "RUBRACA": 1.7351774713590231, "RYBELSUS": 3.5896790279573865, "SAXENDA": 4.842495478386171, "SILDENAFIL": 1.903735052030142, "SPIRONOLACTONE": 1.2378725896436893, "SUBOXONE": 1.363083919813982, "SUTENT": 2.479481987540652, "SYNAGIS": 3.5512547960246343, "TAGRISSO": 1.2548627971383055, "TASIGNA": 1.628078507094116, "TICAGRELOR": 1.3419734734798745, "TOVIAZ": 1.1396404877639472, "TRELEGY": 1.0248245773184217, "TRULICITY": 4.055070411224713, "UNSPECIFIED": 2.091701002418026, "VARENICLINE": 10.233667434335215, "VICTOZA": 2.349150432909007, "XALKORI": 2.146538766138853, "XELJANZ": 1.1194461114689809, "XYREM": 1.9416918123562896, "ZOSTAVAX": 7.78073378978634, "null": 1.6433041270450743}
\ No newline at end of file
+{"ABACAVIR": 0.3065690327661459, "ABASAGLAR": 0.6495817899886128, "ABILIFY": 0.6979862688191087, "ABRAXANE": 2.8097865473627905, "ACTOS": 2.0211982873275063, "ACTRAPID": 1.117189286477712, "ADENURIC": 1.7296184583635883, "AFINITOR": 2.5629713303267376, "AFLIBERCEPT": 2.335125697382217, "AIMOVIG": 0.2323406003792074, "ALEMTUZUMAB": 0.4121615556950802, "ALIMTA": 2.5152525921022595, "ALISKIREN": 1.4502520488291428, "ALL": 1.3518335391032623, "ALPELISIB": 1.7165213966338917, "AMBRISENTAN": 1.8761138437899656, "AMINOSALICYLIC": 0.4798186133052752, "ANORO": 0.2339712098517904, "ANTIBIOTICS": 2.3613410225594245, "APIDRA": 1.003975250824868, "APIXABAN": 3.873489858526411, "APROVEL": 3.039183739363568, "ARANESP": 0.575108091839289, "ARAVA": 0.146927099786044, "ARIPIPRAZOLE": 0.7120698278829112, "ASPARAGINASE": 0.2980163699850699, "ATAZANAVIR": 0.2526503080805731, "ATEZOLIZUMAB": 3.5024827283545834, "ATRIPLA": 0.0658283348049809, "AUBAGIO": 0.6980806524491255, "AVANDIA": 0.2443544062231174, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3425.json
index 81ca63e03b9..978a8eaa610 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3425.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3425.json
@@ -1 +1 @@
-{"null": 3.8425457006871793}
\ No newline at end of file
+{"null": 0.9004185235913372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3426.json
index a580ee50d3d..65b0fa474f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3426.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3426.json
@@ -1 +1 @@
-{"null": 4.008083520529888}
\ No newline at end of file
+{"null": 1.7424497548446465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3427.json
index 682bbd6b769..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3427.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3427.json
@@ -1 +1 @@
-{"BIKTARVY": 39.71666788395807, "CYMBALTA": 4.544084198973321, "ELIQUIS": 5.708181425065748, "GENVOYA": 58.36946654505461, "ISENTRESS": 37.44770735181053, "JANUMET": 11.85000713548491, "JANUVIA": 13.692366248616723, "MIMPARA": 155.17940999063666, "SYNAGIS": 16.171757107267304, "ZAVESCA": 255.98396991124983}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3428.json
index f70adb89daf..3bf050b43b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3428.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3428.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 3.355255353087626, "FYCOMPA": 27.749640592152737, "GARDASIL": 4.161020548772105, "INFANRIX": 16.670475127604053, "MMRVAXPRO": 15.768668091530634, "NIMENRIX": 4.665709502045421, "OLANZAPINE": 3.1894547602953405, "PREVENAR": 32.24226145336513, "ZYPREXA": 2.1670657168287693, "null": 2.948566669567294}
\ No newline at end of file
+{"KEPPRA": 30.659884840400814, "null": 0.8190382373904889}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3429.json
index 479150177d5..9d0248a0479 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3429.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3429.json
@@ -1 +1 @@
-{"null": 1.474794731145718}
\ No newline at end of file
+{"null": 1.2697170836939948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/343.json
index 89170832981..d8ff5fb4e76 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/343.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/343.json
@@ -1 +1 @@
-{"ABATACEPT": 5.919864396869161, "ADALIMUMAB": 4.040362564710142, "AERIUS": 1.4503889495655722, "AIMOVIG": 1.3745424774474917, "ALISKIREN": 7.837733242049719, "ALL": 2.722934579715965, "AMINOSALICYLIC": 3.808849611886302, "APIXABAN": 7.154508936557738, "APREMILAST": 11.50680238375522, "AVANDAMET": 2.891006817442729, "AVANDIA": 2.463285906066578, "BENLYSTA": 1.2722785763164837, "BRINTELLIX": 1.246224869857918, "BRIVIACT": 1.6711991477861812, "BUMETANIDE": 3.889045767515914, "BUPRENORPHINE": 1.1948869178330874, "CANNABIDIOL": 4.44433280579396, "CHAMPIX": 4.975530921435935, "CYMBALTA": 2.027742381225784, "DULOXETINE": 1.101884601169127, "ENTYVIO": 1.4335147084946418, "ENZALUTAMIDE": 2.617336120980133, "FAMPYRA": 1.510598053414764, "FENTANYL": 1.3436751106325275, "FESOTERODINE": 32.82498513043153, "FYCOMPA": 2.469953105065148, "GARDASIL": 1.9422530509686025, "HUMALOG": 1.4912223906254969, "IBRANCE": 1.0692092346898248, "INTRONA": 2.357081350582774, "IRON": 2.7808194490059823, "KEPPRA": 3.9687668562683567, "LANTUS": 1.3584336704312925, "LATUDA": 1.4391110615339973, "LYRICA": 3.2790992933892125, "MELATONIN": 1.705079650705713, "MICARDIS": 1.2923756547430578, "MIDAZOLAM": 1.900105697668008, "NINLARO": 1.0909711724713826, "OLANZAPINE": 1.3645337102782256, "OXYBUTYNIN": 3.848524935106429, "PEGASYS": 1.7929884174967838, "PEGINTRON": 2.071123063389523, "PLAVIX": 1.5255826005873252, "PROTELOS": 5.049670818159369, "RANEXA": 3.06078726370813, "RAPAMUNE": 1.2661547398455582, "RISPERIDONE": 1.4444891430943, "SIFROL": 1.5105624892866487, "SUBOXONE": 1.1955891730391135, "SUBSTANCE": 58.49653583304914, "TAMIFLU": 1.8498221583806345, "TIVICAY": 2.595667529497314, "TOVIAZ": 1.2318523277702245, "ULTIBRO": 9.285647470349865, "VIAGRA": 2.182108693692677, "VIMPAT": 4.040217485068628, "XTANDI": 2.4786911840725074, "XYREM": 2.1995343898763675, "ZYPADHERA": 2.9605379745798617, "ZYPREXA": 1.2571967014560936, "null": 1.5404140378521285}
\ No newline at end of file
+{"null": 0.607446179040787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3430.json
index 6fd2c7ad909..090770be764 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3430.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3430.json
@@ -1 +1 @@
-{"ABRAXANE": 91.3961623391678, "AZACITIDINE": 22.397063404129423, "BEVACIZUMAB": 13.123366378641212, "CYTARABINE": 7.588635848261394, "DARUNAVIR": 57.87411781017406, "DEXAMETHASONE": 10.460209424592335, "GEFITINIB": 76.17624291310764, "IMATINIB": 62.62944124860421, "IRESSA": 30.909304431817933, "IRINOTECAN": 18.496858498157557, "SOLIRIS": 18.92707525505111, "SPRYCEL": 30.13713785139111}
\ No newline at end of file
+{"null": 2.044969251576027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3431.json
index a88290509e4..e0153b92f29 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3431.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3431.json
@@ -1 +1 @@
-{"GLIVEC": 112.40264336280148, "STRIBILD": 16.558650560064695, "TASIGNA": 96.46885624299524, "TRUVADA": 4.908400027954089}
\ No newline at end of file
+{"ARANESP": 47.87305236498157, "CELLCEPT": 34.44904772137481, "MYCOPHENOLATE": 213.09868682027556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3432.json
index 1d0fdac4368..1ab51d5afe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3432.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3432.json
@@ -1 +1 @@
-{"null": 3.524007618038884}
\ No newline at end of file
+{"PRIVIGEN": 495.4914508169246, "null": 0.5790785496784607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3433.json
index bcedbc0614f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3433.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3433.json
@@ -1 +1 @@
-{"null": 1.1329568019540135}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3434.json
index 368cb6a729e..2b0a265f9a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3434.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3434.json
@@ -1 +1 @@
-{"COSENTYX": 1.124015122274515, "ENTRESTO": 4.123896193324312, "EXFORGE": 4.07628895957286, "EXJADE": 3.273542237884899, "FORSTEO": 1.4588758325294031, "HUMALOG": 1.267083709998133, "JAKAVI": 6.987425868536882, "MEPOLIZUMAB": 3.0153835563807547, "OMALIZUMAB": 5.327959102795035, "SIMPONI": 4.184310520707913, "SUTENT": 1.86664351727493, "TRACLEER": 2.351162456505008, "XOLAIR": 1.987024445050661, "XTANDI": 1.8992604762514973, "ZYPREXA": 1.0733810163864317, "null": 1.199730839594633}
\ No newline at end of file
+{"BUSULFAN": 128.91979612676494, "null": 1.1804774994225942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3435.json
index de2b0c97ccb..d970317d345 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3435.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3435.json
@@ -1 +1 @@
-{"ABATACEPT": 4.2219580720072685, "ACLASTA": 3.7396188839798192, "ACTRAPID": 1.554510731556478, "ADALIMUMAB": 6.285952389807419, "ADCIRCA": 1.3897022597215554, "ADENURIC": 1.1408355175645208, "ADVAGRAF": 2.374009487131179, "AFINITOR": 2.468976506471777, "ALIMTA": 3.3219538157415496, "AMIKACIN": 1.22793575965664, "AMINOSALICYLIC": 1.7155267351689745, "APREMILAST": 5.652607483802892, "APREPITANT": 12.675750125958908, "ARANESP": 11.250323339128803, "ARAVA": 3.724061040242344, "ATEZOLIZUMAB": 1.5202764670624993, "AVASTIN": 1.3535044483277412, "AVELUMAB": 3.742244031194057, "AXITINIB": 2.698083704506822, "AZILECT": 2.557411651368657, "BEDAQUILINE": 1.8400504999890093, "BENZODIAZEPINE": 1.065088515047402, "BEVACIZUMAB": 1.7591248123073189, "BOSENTAN": 2.3440078165387006, "BRAFTOVI": 1.3229511583965168, "CABOMETYX": 1.586970867667454, "CAELYX": 1.3155020223032774, "CAPECITABINE": 1.626547226997512, "CARBIDOPA": 1.2308357356882256, "CASPOFUNGIN": 1.0893769828402653, "CEFTAROLINE": 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1.011582382120068, "PEGFILGRASTIM": 7.686962778184768, "PEMBROLIZUMAB": 2.876840895024185, "PEMETREXED": 2.038273245465963, "PLUVICTO": 35.30781526467567, "POMALIDOMIDE": 3.289642555122611, "PRADAXA": 1.7107839492023862, "PRAXBIND": 2.672000515512168, "RAPAMUNE": 1.7011981512468068, "RASBURICASE": 8.370152932510361, "RASILEZ": 1.0399622014944, "REBETOL": 1.4606419440057112, "REGORAFENIB": 3.087177415854483, "REMDESIVIR": 2.3493561834712917, "REVATIO": 1.038714569764014, "RISPERIDONE": 1.0959582116200934, "RITUXIMAB": 1.369386364443465, "ROTATEQ": 1.0269807502099857, "RUXOLITINIB": 1.2228429926977331, "SIFROL": 1.8719111781795603, "SILDENAFIL": 1.7238152461825982, "SOLIRIS": 1.6896639415912085, "SORAFENIB": 1.4533973190410678, "SPINRAZA": 1.8134478750515584, "SPIRONOLACTONE": 1.1550900593247144, "STALEVO": 3.102061139066422, "STIVARGA": 2.7473036898688576, "SUSTIVA": 3.373776232891266, "SUTENT": 1.6173697584797275, "SYNAGIS": 1.55279426831822, "TAFINLAR": 2.256908028393501, "TAGRISSO": 1.7550839007064245, "TELMISARTAN": 1.2401447626987343, "TEMODAL": 1.4839867586726654, "TEMOZOLOMIDE": 1.1274073693703557, "THALIDOMIDE": 1.1059991610898607, "TOBRAMYCIN": 1.7143184097250124, "TOPOTECAN": 1.0533238438661254, "TORISEL": 3.765928004252657, "TRACLEER": 1.6633232619512368, "TRODELVY": 3.293896312853976, "TWINRIX": 1.6655228403146731, "VECTIBIX": 1.438102444862371, "VEKLURY": 1.5947047598307078, "VEMURAFENIB": 2.1638242702828627, "VENCLYXTO": 3.713192362780255, "VENETOCLAX": 1.908762819626015, "VFEND": 1.070543254083685, "VORTIOXETINE": 3.142239720835997, "VOTRIENT": 1.6504960874054155, "XALKORI": 1.7141064119241805, "XOFIGO": 19.89063277251192, "XTANDI": 2.547642216100543, "YERVOY": 2.561426451371126, "ZAVESCA": 4.599047971530279, "ZELBORAF": 1.30685236833259}
\ No newline at end of file
+{"BRIDION": 37.4221123560941, "BUPIVACAINE": 22.249468273904345, "FENTANYL": 65.67188525355341, "MIDAZOLAM": 30.525220985033773, "null": 4.411212659676671}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3436.json
index 8085ddd4dcd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3436.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3436.json
@@ -1 +1 @@
-{"AMGEVITA": 717.8213894303317, "ARAVA": 1.1171792589641798, "CRIXIVAN": 32.72172983031557, "ENTYVIO": 7.037574120874548, "FAMPYRA": 11.966220429530866, "GARDASIL": 3.753457570897822, "HUMIRA": 10.94581230412594, "LEFLUNOMIDE": 35.48625296959275, "RINVOQ": 11.243500433951178, "null": 1.455971052074242}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3437.json
index 76d8582a578..8b0582d0dfe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3437.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3437.json
@@ -1 +1 @@
-{"AVAMYS": 9.118546655741898, "CYMBALTA": 2.8123640446470817, "GARDASIL": 12.27009129444493, "LYRICA": 5.57112066664281, "OLANZAPINE": 5.024530229898881, "ZOSTAVAX": 18.170285042452846, "ZYPREXA": 3.138172305162715, "null": 1.859769843991813}
\ No newline at end of file
+{"ABATACEPT": 3.726424469169743, "ABILIFY": 1.6270183690777562, "ADALIMUMAB": 3.8278406820717272, "ADCIRCA": 5.184076086513179, "AFINITOR": 0.2303084630877056, "ALIMTA": 0.4352057408208452, "AMINOSALICYLIC": 3.3374459652188064, "APIDRA": 0.2867652344630063, "APREMILAST": 15.28440478114908, "ARANESP": 0.3093751423933461, "ARAVA": 0.2024464605218192, "ARIPIPRAZOLE": 2.220100546574607, "AVASTIN": 0.5781216599292042, "AXURA": 16.60492679529581, "AZILECT": 5.111232322887941, "BLINATUMOMAB": 3.134748968349476, "BRAFTOVI": 0.5962227055061746, "BRIDION": 0.7238254451315853, "BRINTELLIX": 0.3715014863463604, "BRIVARACETAM": 2.9891997513517103, "BUPIVACAINE": 5.598665304885513, "BUPRENORPHINE": 2.0196034322170187, "BYETTA": 0.3879170585557533, "CANCIDAS": 3.3458247726527013, "CAPECITABINE": 0.5330658145074684, "CARBIDOPA": 2.2354989701921126, "CELECOXIB": 2.1215650104732147, "CELLCEPT": 0.5930576736590858, "CHAMPIX": 0.9557172368203526, "CICLOSPORIN": 0.393161916289801, "CLOPIDOGREL": 0.7745654752436761, "COAPROVEL": 0.6499174343141474, "COMIRNATY": 0.1470534400694344, "COMTAN": 4.029557949027159, "COSENTYX": 0.5523405218584982, "CYMBALTA": 1.251439350096173, "CYTARABINE": 0.4140784099722931, "DARZALEX": 0.7308485469743043, "DEXAMETHASONE": 1.3745795703020351, "DEXDOR": 8.969880033973977, "DEXMEDETOMIDINE": 22.479984511656056, "DOXORUBICIN": 1.1819137931172912, "DULOXETINE": 2.853134565168247, "EBIXA": 4.159166451388753, "ELIQUIS": 0.48476444232378, "ENOXAPARIN": 0.7914431614949298, "ENTACAPONE": 2.3457006208151205, "ENTRESTO": 0.5065246648353695, "ENTYVIO": 0.3155340447672268, "EPADERM": 43.54642460147096, "ERTAPENEM": 9.131286815894953, "ESOMEPRAZOLE": 3.096531357873908, "EXFORGE": 0.5929052567961061, "FAMPYRA": 0.4334462386603389, "FENTANYL": 3.170692164644548, "FORSTEO": 0.306168447962195, "FORXIGA": 0.2653360344205974, "FYCOMPA": 2.337125726675548, "GARDASIL": 0.1446252087213772, "HALAVEN": 1.140962186013815, "HARVONI": 0.4579360978536809, "HUMALOG": 0.1512981476591683, "HYDROCORTISONE": 0.855397321127588, "IBRANCE": 0.1262605380352289, "IBUPROFEN": 1.087399833818018, "INSULIN": 0.3700764432992962, "INVANZ": 16.920843032439628, "IRESSA": 0.601730646664625, "JAKAVI": 0.2385731128813967, "JANUVIA": 0.4452344745975214, "JARDIANCE": 0.9383542021566754, "KALETRA": 0.7129524780986093, "KEPPRA": 1.771271153603956, "KEYTRUDA": 1.278513220414515, "KYMRIAH": 1.6460240959632413, "LANTUS": 0.3430587664811733, "LATUDA": 1.0234006978729062, "LEVETIRACETAM": 2.2967244584468376, "LEVODOPA": 4.631684178419766, "LEVOFLOXACIN": 2.4341378884500124, "LYRICA": 2.4551177804461592, "MEKINIST": 0.6074173666119376, "MELATONIN": 3.220638765757424, "MEMANTINE": 3.2981429538376545, "METHOTREXATE": 0.3035243333384338, "MIDAZOLAM": 5.535893806952667, "MYCOPHENOLATE": 0.7718823918499218, "NEXAVAR": 0.4722940951349252, "OCRELIZUMAB": 0.3677334804521409, "OLANZAPINE": 6.625848822800921, "OPDIVO": 1.000291723736291, "OPSUMIT": 0.1763771279962563, "OXYBUTYNIN": 4.858517220410068, "PANTOPRAZOLE": 1.093952589656299, "PEGASYS": 0.6323947516697641, "PEGINTERFERON": 0.4709688129448872, "PEGINTRON": 0.8418803249170321, "PLAVIX": 0.3061397529009367, "PREGABALIN": 2.4139822123802035, "REVATIO": 0.4296981812720006, "RISPERIDONE": 3.1082039489478555, "RITUXIMAB": 0.6475468524166297, "RIVAROXABAN": 4.4988662113327855, "SHINGRIX": 0.4317533561012606, "SIFROL": 6.279004804662711, "SOLIRIS": 0.2305020895537448, "SPIKEVAX": 0.2387756113840948, "STALEVO": 4.6624987622591725, "STELARA": 0.1350821699584001, "STIVARGA": 0.4587406848037533, "SUBOXONE": 0.7217547326195864, "SUTENT": 0.3389631776914, "SYCREST": 2.5435506695251493, "TACROLIMUS": 3.1871101315817185, "TAGRISSO": 0.4757642666544569, "TAMIFLU": 17.935615857079814, "TOVIAZ": 0.5476778954074681, "TOZINAMERAN": 0.454632093449048, "TRACLEER": 0.3747653443039021, "VAXZEVRIA": 0.3719425059828016, "VFEND": 16.57086471565189, "VIMPAT": 1.789183991296596, "VORICONAZOLE": 11.0079677980353, "VOTRIENT": 0.3127152595639215, "XELJANZ": 0.147099430313381, "XTANDI": 0.7362891564971826, "YESCARTA": 1.698125739045972, "ZYPADHERA": 15.587739702654378, "ZYPREXA": 5.092557345386584, "null": 2.106666778709293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3438.json
index c4de1c150b1..978b50aef45 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3438.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3438.json
@@ -1 +1 @@
-{"null": 2.23656444563837}
\ No newline at end of file
+{"COMIRNATY": 0.6749994189312857, "MMRVAXPRO": 29.912972887841025, "SPIKEVAX": 2.7050102831812604, "TAMIFLU": 48.52835963855505, "VAXZEVRIA": 2.4687283376907296, "null": 0.1638501900442117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3439.json
index 122906763cc..8141743145b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3439.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3439.json
@@ -1 +1 @@
-{"AFINITOR": 2.8778620779073507, "ALIMTA": 3.466945943486511, "APIDRA": 1.2960920172630426, "AVANDIA": 3.16527752348487, "BARACLUDE": 4.167501468500933, "BEDAQUILINE": 2.073654900839456, "BINOCRIT": 20.58629853871493, "BUDESONIDE": 1.764128318733744, "BUMETANIDE": 6.6065137159538185, "BUSULFAN": 1.91822485168119, "BYETTA": 1.398000556769175, "CELLCEPT": 1.0501561131224684, "CICLOSPORIN": 2.9182001230267924, "CIMZIA": 1.409325180606114, "ENTRESTO": 1.7975932771046856, "EXFORGE": 5.260750835741959, "EXJADE": 1.7591404868798526, "FASENRA": 2.1089210727636485, "GALVUS": 3.4019329067955275, "GLIVEC": 8.991406170302016, "HERCEPTIN": 1.7850168853911632, "IBUPROFEN": 1.285970053515328, "IMATINIB": 11.580828066156808, "INCIVO": 1.5671580401076284, "INSULIN": 2.0070549406194624, "IRON": 4.682283903525589, "JANUMET": 1.5570123089087806, "JANUVIA": 1.9492991620302316, "LANTUS": 1.5770110776283566, "LENVIMA": 2.045157432292528, "LEVETIRACETAM": 1.6002785678214135, "LONSURF": 1.824666546541192, "LYRICA": 1.2520433210875803, "MICARDIS": 2.3712598512539462, "OPSUMIT": 2.2570327864732005, "PEGASYS": 1.0643699619617046, "PEGINTERFERON": 1.35613266441564, "PEGINTRON": 1.379909308548417, "PEMBROLIZUMAB": 1.5508172951519363, "RASILEZ": 5.463655145441369, "REVATIO": 1.5274949900926749, "ROACTEMRA": 1.1520218290234454, "SILDENAFIL": 1.925179839169484, "SOLIRIS": 1.0426153819858892, "SPRYCEL": 3.022556364643147, "SUTENT": 2.37416173373596, "TASIGNA": 1.8569220918607, "TOVIAZ": 1.9050958341723532, "TRACLEER": 3.744146053088675, "VFEND": 1.5470429670089627, "VOTRIENT": 1.7770227125199574, "XALKORI": 4.499413095760138, "XTANDI": 1.3566593936306872, "ZYPREXA": 1.7092444533663451, "null": 1.5213041912579086}
\ No newline at end of file
+{"null": 2.287951471594365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/344.json
index 4d41e97b93d..179834bb17b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/344.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/344.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4442510975399103, "null": 1.0378361049443532}
\ No newline at end of file
+{"BUDESONIDE": 12.034971753495077, "COMIRNATY": 0.2976666490122004, "HYDROCORTISONE": 33.57215169695287, "IPILIMUMAB": 14.090822527498725, "KEYTRUDA": 16.49358859672793, "OPDIVO": 27.73348853346601, "SPIKEVAX": 0.337269490537142, "TOZINAMERAN": 1.0819964155063586, "VAXZEVRIA": 0.4686425965180055, "YERVOY": 21.3103035724141, "null": 0.9174864716966852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3440.json
index 4b68db5d56c..4d9ce708f0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3440.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3440.json
@@ -1 +1 @@
-{"null": 1.624882968930519}
\ No newline at end of file
+{"ATOSIBAN": 3975.062946982816, "COMBIVIR": 19.34553140544672, "CYTARABINE": 35.55598148693523, "null": 1.4483537567390432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3441.json
index 4f8b74e5ea8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3441.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3441.json
@@ -1 +1 @@
-{"ABILIFY": 1.4812604269263354, "AERIUS": 1.2907103229733616, "ASPARAGINASE": 2.338732252311187, "AZACITIDINE": 1.3502600432024805, "BEDAQUILINE": 1.7259130653484522, "BEXSERO": 1.8172344765859785, "BRIVARACETAM": 8.376903608315061, "BRIVIACT": 20.591159463133124, "BUPIVACAINE": 2.4121734829440133, "BUSULFAN": 1.5544462973539606, "CETRORELIX": 56.12817963761371, "CHAMPIX": 1.3136209118990212, "CICLOSPORIN": 1.8475048035107289, "CYMBALTA": 1.3556494074125764, "DARUNAVIR": 1.921715664037985, "DELAMANID": 5.136273980007629, "DESLORATADINE": 2.5828653294725097, "DEXAMETHASONE": 1.6748092605977982, "DEXDOR": 9.923100689383936, "DOLUTEGRAVIR": 4.2633749946342725, "DULOXETINE": 1.5993633556209792, "EBIXA": 5.556787290429658, "EPIDYOLEX": 9.221365612661124, "FAMPRIDINE": 11.65399367869762, "FAMPYRA": 4.798644996758488, "FENTANYL": 3.3452474080702075, "FYCOMPA": 5.354562078945678, "GARDASIL": 3.695166276212011, "HYDROCORTISONE": 1.6329153525189395, "IBUPROFEN": 1.4469044347331488, "INFANRIX": 3.984424650539563, "KEPPRA": 22.691509797373524, "LACOSAMIDE": 19.27628586420693, "LAMIVUDINE": 1.289308428215884, "LEVETIRACETAM": 17.398498038491827, "LEVOFLOXACIN": 1.258589826574854, "LOXAPINE": 14.50084368750199, "MEMANTINE": 3.6486530029508257, "MENVEO": 1.3576369632053404, "MIDAZOLAM": 5.0388484692847335, "MIMPARA": 1.211046645353974, "NIMENRIX": 2.9679871469706884, "NOXAFIL": 1.5500425740612227, "OLANZAPINE": 2.8720648107859748, "OXYBUTYNIN": 4.248019653007331, "PREGABALIN": 1.032770227566293, "REBIF": 5.634915864517315, "RISPERIDONE": 2.0941628084335417, "SILDENAFIL": 1.8279678961526027, "SUFENTANIL": 1.4905845160780604, "SYCREST": 6.330328912397482, "TACROLIMUS": 1.481580770942979, "TAMIFLU": 1.7009563832149974, "TWINRIX": 1.8991113101693105, "VIMPAT": 18.054479368923, "ZYPREXA": 5.9862343331461885, "null": 2.639437953824304}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3442.json
index 2230dcafb0c..506b4e0143c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3442.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3442.json
@@ -1 +1 @@
-{"JARDIANCE": 37.36415549023669}
\ No newline at end of file
+{"ABILIFY": 8.46235153356082, "ARIPIPRAZOLE": 20.00691729912673, "ATRIPLA": 0.1743384761839892, "AZILECT": 8.154149563324761, "BRINTELLIX": 1.250997264588414, "BUPRENORPHINE": 1.2941240271871552, "CARBIDOPA": 15.266700769475868, "CARIPRAZINE": 47.21875423481784, "CHAMPIX": 5.598183751278615, "CLOPIDOGREL": 0.8670608898108885, "COMIRNATY": 0.081030175804367, "COMTAN": 18.32715472714668, "CYMBALTA": 2.0826207847324567, "DAKLINZA": 5.2476077109873644, "DEXAMETHASONE": 0.5862713857991275, "DULOXETINE": 4.682368589519128, "ELIQUIS": 0.2880823418486356, "ENTACAPONE": 32.72418609728828, "ENTRESTO": 0.4739121683571122, "FYCOMPA": 10.619229147939722, "INVEGA": 15.1523578975482, "KAFTRIO": 2.3575120886606955, "KEPPRA": 3.630936393382455, "LACOSAMIDE": 2.9395603900521805, "LATUDA": 18.190018083578504, "LEVETIRACETAM": 7.289089776186576, "LEVODOPA": 19.5775776476232, "LEVOFLOXACIN": 0.6072122935669366, "LURASIDONE": 35.31515533057852, "LYRICA": 2.097839379479247, "NEUPRO": 27.76609363995252, "OLANZAPINE": 14.14007227245848, "PALIPERIDONE": 20.998724996593538, "PANTOPRAZOLE": 1.817657471451241, "PEGASYS": 1.6524815722865702, "PEGINTRON": 2.635276954199362, "SIFROL": 5.636504886584267, "SPIKEVAX": 0.1395586251673003, "STALEVO": 7.979028547149376, "SUBOXONE": 1.829196317259195, "TAMIFLU": 14.63523803697848, "TOZINAMERAN": 0.1595103166991793, "VAXZEVRIA": 0.1872491473560309, "VFEND": 3.317644910641018, "VIMPAT": 2.5948779157056894, "XYREM": 5.735166811737682, "ZYPADHERA": 3.6048305583936657, "ZYPREXA": 8.217355103437207, "null": 2.127633685229819}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3443.json
index df614970681..f4b7a4f8778 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3443.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3443.json
@@ -1 +1 @@
-{"null": 6.272130450456058}
\ No newline at end of file
+{"ARIPIPRAZOLE": 417.3659677444808, "CARIPRAZINE": 687.8930317540205, "OLANZAPINE": 18.811626170299707, "null": 0.836557425909326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3444.json
index d0e9fae7269..88f2b0368d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3444.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3444.json
@@ -1 +1 @@
-{"null": 7.229322137377884}
\ No newline at end of file
+{"null": 1.3872398812792184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3445.json
index c640ce065e0..27ac2889550 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3445.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3445.json
@@ -1 +1 @@
-{"JARDIANCE": 35.10771013966773}
\ No newline at end of file
+{"null": 1.3683240990509835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3446.json
index 8c8cbb474f3..f52426dfd20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3446.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3446.json
@@ -1 +1 @@
-{"FORXIGA": 27.206930303027928, "JARDIANCE": 55.69864914855376, "SUTENT": 1.4607613370126509, "null": 1.6910495601993485}
\ No newline at end of file
+{"OLANZAPINE": 120.22690709364888, "null": 0.518568421952164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3447.json
index 30a6eecf643..79c094d3918 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3447.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3447.json
@@ -1 +1 @@
-{"COSENTYX": 10.840906674017862, "FORXIGA": 78.82024705584077, "JARDIANCE": 159.89938037319976}
\ No newline at end of file
+{"ABILIFY": 152.39732773196494, "null": 0.9918639202267614}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3448.json
index aa8b6ba662f..711e9149b02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3448.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3448.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2397179902275988, "JARDIANCE": 23.075812549401217}
\ No newline at end of file
+{"ARIPIPRAZOLE": 16.96926309068697, "null": 2.2075425315915918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3449.json
index 8162f897b25..943c59d8dc6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3449.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3449.json
@@ -1 +1 @@
-{"FORXIGA": 33.901066116527474, "JARDIANCE": 34.518564593873194, "SUTENT": 5.659817539071863, "null": 1.0796194124322966}
\ No newline at end of file
+{"TOZINAMERAN": 1.6056483202673837, "null": 1.9469439228832288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/345.json
index cba75803e9d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/345.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/345.json
@@ -1 +1 @@
-{"null": 1.200916273065125}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3450.json
index ae772c34dd8..62c247c59bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3450.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3450.json
@@ -1 +1 @@
-{"AP": 7210.221152950711, "KONTRASTMITTEL": 10901.437672281838, "null": 1.752443510476028}
\ No newline at end of file
+{"ABILIFY": 1.2570158631465091, "AIMOVIG": 0.637332519761946, "APIDRA": 1.1129686962416976, "APIXABAN": 0.6825063989593265, "ARANESP": 1.05306067692075, "ARAVA": 0.1491312487157, "ATRIPLA": 0.0807726935972652, "AUBAGIO": 0.7119850282754446, "AVANDIA": 0.8071557765135965, "BOSULIF": 2.154371009725012, "BRAFTOVI": 1.0262807571736938, "BYDUREON": 0.827515670091279, "CHAMPIX": 0.2556538642825374, "CIMZIA": 0.2980517284220903, "CLOPIDOGREL": 1.44834690883464, "COMIRNATY": 0.1722251921624121, "COMTAN": 3.33866622885214, "COSENTYX": 0.6739334136513783, "CYMBALTA": 1.5733889748770185, "DENOSUMAB": 10.379835404757944, "DESCOVY": 4.217723472858996, "DEXAMETHASONE": 1.033808710480307, "DULOXETINE": 0.8073054524393043, "EBIXA": 7.231702824859253, "ELIQUIS": 6.964413493424049, "ENTACAPONE": 5.7229377599229245, "ENTRESTO": 2.07362891943684, "ERLEADA": 2.9628039732118605, "ESBRIET": 1.10304966424331, "EVENITY": 6.38362169263948, "EXFORGE": 1.293406225525235, "EXJADE": 0.7814047979418831, "EYLEA": 2.5052528766659714, "FENTANYL": 0.3410329935779014, "FORSTEO": 0.667979347475747, "GARDASIL": 0.1495514120922159, "HARVONI": 0.9985572809028206, "HUMALOG": 6.700138928755196, "IBRANCE": 4.13044250844346, "INCRUSE": 2.224813248590635, "INLYTA": 1.269887337012651, "INSULIN": 2.4934080517172545, "INTRONA": 3.0672261014682647, "IRESSA": 1.3122644525204152, "JAKAVI": 0.8019915175361392, "JANUMET": 2.130103848266002, "JANUVIA": 2.2594358235708087, "JARDIANCE": 4.728067211820578, "KEPPRA": 1.3896902754022271, "KEYTRUDA": 0.7101274944834541, "LANTUS": 6.567366356572887, "LATUDA": 1.7699351534112164, "LEVEMIR": 3.5024643680462155, "LEVETIRACETAM": 0.4421254340468081, "LEVODOPA": 3.374356363861173, "LYRICA": 2.385588692317832, "MEMANTINE": 8.75329344637986, "METFORMIN": 5.124658783209105, "MICARDIS": 2.3367636678301587, "MIMPARA": 3.6802490962045935, "NEULASTA": 2.8494642604634706, "NEXAVAR": 0.3511777165837544, "NINLARO": 2.2700589236002946, "NPLATE": 0.9265478504300976, "OFEV": 1.118734381250433, "OLANZAPINE": 1.2737587036595444, "OPDIVO": 0.6111600443793425, "OPSUMIT": 0.8184947866643955, "OXYBUTYNIN": 4.540028859091814, "PEGASYS": 0.1398995836363302, "PEGINTRON": 1.19057388458583, "PLAVIX": 0.92760633760382, "PREGABALIN": 0.96354808708129, "RANOLAZINE": 7.619257816376308, "RAPAMUNE": 2.853508995015115, "REVATIO": 1.7080667417827742, "RISPERIDONE": 2.26469208410736, "ROACTEMRA": 0.6572682648310612, "RUBRACA": 1.4352739684404845, "SIFROL": 3.323804362684906, "SIMPONI": 1.3899450873999235, "SOLIRIS": 0.5026532133806776, "SPIKEVAX": 0.2179577239581119, "SPIRONOLACTONE": 5.34235615452441, "SPRYCEL": 1.460081394025048, "STALEVO": 6.316883951515079, "STELARA": 0.5436167417795141, "SUTENT": 0.3390152412835068, "TAGRISSO": 1.5407403166251616, "TAMIFLU": 0.522387858359902, "TASIGNA": 0.7798533268063711, "TOUJEO": 6.092282818276282, "TOVIAZ": 18.64045421702887, "TOZINAMERAN": 0.3719392199751594, "TRACLEER": 0.5680672328869668, "TRELEGY": 3.375555344364478, "TRULICITY": 3.1000158853589075, "VAXZEVRIA": 0.0951297887539152, "VIAGRA": 1.610345934815859, "VICTOZA": 1.3852606629276762, "VIMPAT": 1.2663083623248164, "XALKORI": 1.2258049495080658, "XELJANZ": 2.927078286129711, "XTANDI": 4.215567406105599, "ZOSTAVAX": 1.0078661741172574, "ZYPREXA": 1.4485098244183972, "null": 1.5191662127197971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3451.json
index e61fb48a3dc..e31cbacb5da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3451.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3451.json
@@ -1 +1 @@
-{"FORXIGA": 42.676746027912806, "JARDIANCE": 74.28538473195147, "SUTENT": 5.40134910345629, "null": 1.1240446930294332}
\ No newline at end of file
+{"APIDRA": 1.6093999469313094, "BYETTA": 1.40351661247014, "CELECOXIB": 8.361621715817536, "COMIRNATY": 0.0984316649962667, "CYMBALTA": 1.1647398458247185, "EBIXA": 17.77008851652304, "ELIQUIS": 5.521987859704324, "EPADERM": 309.6623483634038, "EXELON": 47.43302399078536, "EXFORGE": 1.998919395441053, "FORSTEO": 1.3999382461901684, "HUMALOG": 9.089867364154795, "IBRANCE": 2.7726567223217184, "INSULIN": 2.6357814888686493, "IRON": 17.655455866590955, "JANUMET": 2.2006026242879404, "JANUVIA": 1.174918637593046, "KEPPRA": 1.271496226884333, "LANTUS": 9.257704216671636, "LEVEMIR": 7.022619150354636, "MEMANTINE": 18.50834631317517, "OLANZAPINE": 0.7815813271409816, "PEGINTRON": 0.6893782043945047, "SIMPONI": 0.7826859384606004, "SPIKEVAX": 0.1007751687303762, "SUTENT": 0.358562766057118, "TOVIAZ": 6.946127994218147, "TOZINAMERAN": 0.2159091624724282, "TRELEGY": 2.3444736695798403, "TRULICITY": 3.838791649060912, "VAXZEVRIA": 0.0433707960641711, "VIAGRA": 3.2188180739151204, "XELJANZ": 3.300590187517864, "XTANDI": 2.241627140416161, "ZOSTAVAX": 1.280854294147464, "ZYPREXA": 1.9049713555489587, "null": 2.050918280196413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3452.json
index 3415adf36a9..7235cffca44 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3452.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3452.json
@@ -1 +1 @@
-{"BRILIQUE": 6.435570101767847, "CLOPIDOGREL": 3.386717615947022, "ELIQUIS": 4.263292680672584, "JARDIANCE": 2.225091119975347, "SUTENT": 1.8443668776230853, "null": 1.9787536506590084}
\ No newline at end of file
+{"ZYPREXA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3453.json
index 749d8385c39..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3453.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3453.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.4168380181832183, "COMIRNATY": 2.668360842875378, "COVID19": 1.402721036992568, "ENBREL": 1.730853199340013, "GARDASIL": 1.6269368483794542, "JARDIANCE": 2.227080194877809, "RINVOQ": 19.003009222257848, "SHINGRIX": 4.082154682408016, "SIMPONI": 2.145007993156504, "SPIKEVAX": 1.2538817208174005, "STELARA": 1.647818470755047, "TOZINAMERAN": 1.9553639321435008, "XELJANZ": 1.2130927524245243, "ZOSTAVAX": 4.811531776866793}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3454.json
index 64771fa2996..970f7177196 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3454.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3454.json
@@ -1 +1 @@
-{"ZOSTAVAX": 18.867533534476784}
\ No newline at end of file
+{"OLANZAPINE": 26.06719279211566, "null": 1.2081618230904576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3455.json
index e9529723ac8..a4705970e9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3455.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3455.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6319815922482517, "RINVOQ": 70.67250293088274, "SHINGRIX": 24.78772370011829, "ZOSTAVAX": 39.46231972736071}
\ No newline at end of file
+{"CLADRIBINE": 2691.150075743304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3456.json
index 33b61d7000b..51c824517cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3456.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3456.json
@@ -1 +1 @@
-{"BRINTELLIX": 18.311069581603167, "VIAGRA": 43.04346605830896, "null": 4.030809328257837}
\ No newline at end of file
+{"ARAVA": 1.433126809822212, "CICLOSPORIN": 3.5503715151129707, "CIMZIA": 2.549052433408721, "COMIRNATY": 0.600854611054035, "KEYTRUDA": 2.5635712512294084, "PEGASYS": 2.397865990226409, "SHINGRIX": 5.470552204905991, "SIMPONI": 3.4090317937624186, "SPIKEVAX": 0.3954877700290989, "TOZINAMERAN": 1.0164084777063285, "VAXZEVRIA": 0.6627695501374502, "null": 0.4846782199604013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3457.json
index 361b7fe8287..fd409fc5d64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3457.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3457.json
@@ -1 +1 @@
-{"FORXIGA": 145.0537804183924, "JARDIANCE": 622.6050510271971}
\ No newline at end of file
+{"ADALIMUMAB": 0.3361389514892691, "ARAVA": 1.9534333660991936, "AUBAGIO": 3.10289425541954, "CICLOSPORIN": 2.5480595950065887, "CIMZIA": 2.281568595564829, "COMIRNATY": 0.7540839556002309, "COSENTYX": 1.2751770235856577, "ENBREL": 2.6716017515131005, "GARDASIL": 11.827197393323337, "HUMIRA": 9.7830617165475, "PEGASYS": 0.8338370407625698, "PEGINTRON": 1.94394604759672, "ROACTEMRA": 3.915363965810154, "SHINGRIX": 2.742384673431669, "SIMPONI": 18.98522548038488, "SPIKEVAX": 0.2580408811674639, "TOZINAMERAN": 1.0070069623742903, "TWINRIX": 7.087642895744789, "VAXZEVRIA": 0.5987626732117465, "ZOSTAVAX": 1.6238827944575676, "null": 0.5672334261423885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3458.json
index 2607edc677e..28b0e00b329 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3458.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3458.json
@@ -1 +1 @@
-{"FORXIGA": 309.191941329436, "JARDIANCE": 136.11923258133635}
\ No newline at end of file
+{"AMINOSALICYLIC": 9.010566589529642, "APIDRA": 7.022456381825668, "BENLYSTA": 28.03295257333437, "COMIRNATY": 0.1836705035484649, "LANTUS": 1.880775599835081, "SIMPONI": 37.64142926552065, "STELARA": 5.802842051387911, "SUTENT": 1.5682747515984656, "VAXZEVRIA": 0.206697907151771, "null": 0.8932385079888968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3459.json
index 1e815a5a1b9..201bed90053 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3459.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3459.json
@@ -1 +1 @@
-{"FORXIGA": 81.01304316088434, "JARDIANCE": 571.462430813072}
\ No newline at end of file
+{"CICLOSPORIN": 51.75661242028292, "null": 0.5610331033905649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/346.json
index 64044e5a7c0..1bf04241080 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/346.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/346.json
@@ -1 +1 @@
-{"null": 2.2843330867299185}
\ No newline at end of file
+{"COMIRNATY": 3.775145980829778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3460.json
index b50897bb381..ad74792f2a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3460.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3460.json
@@ -1 +1 @@
-{"FORXIGA": 254.8328181873844, "JARDIANCE": 318.45971060516763}
\ No newline at end of file
+{"NUCALA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3461.json
index 386a74c5b68..5ef66154a9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3461.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3461.json
@@ -1 +1 @@
-{"null": 1.5567030226670393}
\ No newline at end of file
+{"COMIRNATY": 6.567174982408364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3462.json
index e4e277c5b29..a73c86dba65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3462.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3462.json
@@ -1 +1 @@
-{"GANCICLOVIR": 70.14313202692853, "null": 1.1327608665367623}
\ No newline at end of file
+{"ALIMTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3463.json
index c5db9ef9b46..5e92ba3428a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3463.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3463.json
@@ -1 +1 @@
-{"INVEGA": 903.5286584417336}
\ No newline at end of file
+{"null": 0.9978144146412992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3464.json
index 7a2df353abb..5d859cd3203 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3464.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3464.json
@@ -1 +1 @@
-{"COMIRNATY": 2.033515955780333, "FORXIGA": 9.760304600112203, "JARDIANCE": 20.411634626234928, "SPIKEVAX": 1.6054303982707043}
\ No newline at end of file
+{"ELIQUIS": 5.708048983732044, "IBRANCE": 11.219325168304538, "SIMPONI": 29.93283878694057, "null": 0.6762078031113878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3465.json
index 2049bc090a1..e7d04be1324 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3465.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3465.json
@@ -1 +1 @@
-{"null": 2.380186294720142}
\ No newline at end of file
+{"AIMOVIG": 0.8719437281859829, "APIXABAN": 1.0575314033482592, "ATRIPLA": 17.306427976082787, "AUBAGIO": 3.285563600565066, "BIKTARVY": 2.6212489157039336, "BONVIVA": 6.639198397293432, "BUPRENORPHINE": 2.4011771865800062, "CIMZIA": 1.643165556040491, "COMIRNATY": 0.0147511547758783, "COSENTYX": 0.7486536907551227, "CYMBALTA": 0.6372148199644744, "DESCOVY": 13.010340473531096, "ELIQUIS": 1.6387241833369148, "ENBREL": 2.9726413582842217, "FASLODEX": 1.828503829337401, "FORSTEO": 2.320237037927315, "HUMIRA": 1.7328737108902872, "IBRANCE": 0.779503267827767, "METHOTREXATE": 1.3596349745404632, "OLANZAPINE": 0.8374787658253967, "PEGASYS": 2.095454291685986, "PEGINTRON": 1.2841151393740105, "RITUXIMAB": 2.657310799911742, "STELARA": 0.9095950676896356, "STRIBILD": 4.099300429734812, "SUBOXONE": 12.260222937451568, "SUTENT": 0.5269479409247282, "TRUVADA": 4.4449558645243314, "XELJANZ": 0.923800795783964, "ZYPREXA": 1.243258617317775, "null": 1.2437073944944343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3466.json
index 42d2dcca932..37f565f86fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3466.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3466.json
@@ -1 +1 @@
-{"FORXIGA": 27.029737906590864, "JARDIANCE": 23.55505908119773, "SHINGRIX": 5.188881946145443, "SUTENT": 7.368849036097253}
\ No newline at end of file
+{"null": 0.8145643285262828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3467.json
index 42bc7623754..bdf8d9ec621 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3467.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3467.json
@@ -1 +1 @@
-{"FORXIGA": 45.59450032021551, "JARDIANCE": 36.65258157815828, "null": 1.3384601391577244}
\ No newline at end of file
+{"COMIRNATY": 0.7639047714625566, "IBRANCE": 6.219215929886529, "SPIKEVAX": 1.0678414867717048, "VAXZEVRIA": 0.6599247826716765, "null": 1.0653894829211257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3468.json
index 76389bbfb8d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3468.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3468.json
@@ -1 +1 @@
-{"DULAGLUTIDE": 180.75724255187797, "FORXIGA": 67.08217086896731, "JARDIANCE": 152.65840759011948}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3469.json
index d170dc06e12..a97299eff7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3469.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3469.json
@@ -1 +1 @@
-{"JARDIANCE": 12.781005190717526}
\ No newline at end of file
+{"null": 1.0350109550051834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/347.json
index 914cb40f26f..a10800f20fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/347.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/347.json
@@ -1 +1 @@
-{"null": 4.300975156186353}
\ No newline at end of file
+{"COMIRNATY": 0.0513701716955889, "IPILIMUMAB": 68.06164462891408, "KEYTRUDA": 104.72980729757236, "OPDIVO": 314.68175790908253, "PEMBROLIZUMAB": 26.996241241787075, "null": 0.1371461040353902}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3470.json
index 996c980d16b..0268215133d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3470.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3470.json
@@ -1 +1 @@
-{"APTIVUS": 3472.013490665753, "null": 1.582629047157575}
\ No newline at end of file
+{"ELIQUIS": 4.455859852380181, "IBRANCE": 5.714253820543724, "SIMPONI": 20.70251882170237, "XELJANZ": 6.621444420171007, "null": 0.8236314726281694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3471.json
index ce1eeb8fb3b..012fcb52bb2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3471.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3471.json
@@ -1 +1 @@
-{"GARDASIL": 35.76787976752307}
\ No newline at end of file
+{"COMIRNATY": 2.0589716750462825, "VAXZEVRIA": 1.2222911989989622}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3472.json
index 2ae9f4761ec..8deb45f59ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3472.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3472.json
@@ -1 +1 @@
-{"FORXIGA": 82.0181039857135, "JARDIANCE": 330.9175402291273}
\ No newline at end of file
+{"null": 2.135158263087206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3473.json
index e9689f927b8..145cc808efe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3473.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3473.json
@@ -1 +1 @@
-{"ABACAVIR": 4.022235736866002, "ATRIPLA": 2.8460984090956205, "BIKTARVY": 115.6037006985006, "DACLATASVIR": 605.38686445476, "DAKLINZA": 76.88646183118409, "DARUNAVIR": 38.93701901365275, "EMTRICITABINE": 69.99170557169604, "EMTRIVA": 232.04572794552456, "EPCLUSA": 230.96761373882345, "GENVOYA": 109.00034409569749, "HARVONI": 209.12966486986124, "HEPSERA": 38.522496795404365, "ISENTRESS": 19.160371032956075, "RIBAVIRIN": 69.62172040059913, "SOFOSBUVIR": 117.6370637123594, "SOVALDI": 15.422815593871432, "STRIBILD": 10.881243385437315, "TRUVADA": 8.898345177071272, "VEKLURY": 29.40038008298592, "VIREAD": 18.85327797861016}
\ No newline at end of file
+{"ATRIPLA": 41.02085900601698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3474.json
index bc42b277645..4c3de10f412 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3474.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3474.json
@@ -1 +1 @@
-{"CYTARABINE": 181.16345793633465}
\ No newline at end of file
+{"ARAVA": 1.7118354444164046, "FORSTEO": 11.498646097245176, "METHOTREXATE": 39.20010208268797, "PEGASYS": 4.119843891416878, "null": 0.6141067774424899}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3475.json
index 504f5c25b63..60dbfd4175f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3475.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3475.json
@@ -1 +1 @@
-{"BLINATUMOMAB": 4947.162511445805}
\ No newline at end of file
+{"LEVOFLOXACIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3476.json
index e0a230b413f..9cf2cbedaea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3476.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3476.json
@@ -1 +1 @@
-{"ABILIFY": 14.376328160011749, "BIKTARVY": 5.749868437892848, "BUVIDAL": 63.6846969407586, "CIMZIA": 5.495812119432511, "COMBIVIR": 17.74221502584702, "DOLUTEGRAVIR": 33.81449259053695, "DULOXETINE": 7.683572907721872, "HUMALOG": 1.0586408255143396, "KAFTRIO": 10.351004210338186, "KEPPRA": 1.9700926857277852, "LATUDA": 5.311467690673049, "NORVIR": 28.894697793690543, "OLANZAPINE": 9.594948023581908, "STELARA": 2.0095745357204344, "SUBOXONE": 6.122639796010629, "ZYPREXA": 10.068843221680137, "null": 1.5321773510281704}
\ No newline at end of file
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3477.json
index 8ee1b2380e6..0722d6147ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3477.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3477.json
@@ -1 +1 @@
-{"ABILIFY": 24.29753753268703, "AERIUS": 90.61058667821294, "CICLOSPORIN": 3.70354138043252, "CIMZIA": 2.654718599477569, "COMBIVIR": 24.861693204686684, "DUPILUMAB": 532.0404063831385, "GARDASIL": 2.809742312328228, "HUMALOG": 3.919646916994599, "INSULIN": 13.986377020703872, "LEVEMIR": 10.42982170893441, "SUBOXONE": 16.515077802070053, "null": 1.0888442121252293}
\ No newline at end of file
+{"null": 5.190975369480786}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3478.json
index e4b2652f84c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3478.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3478.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3479.json
index 843996499f7..e631993b193 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3479.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3479.json
@@ -1 +1 @@
-{"MMRVAXPRO": 53.6910382152705, "null": 1.624882968930519}
\ No newline at end of file
+{"null": 0.8747763506310584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/348.json
index 6741af1d9ff..2b53e1c8e64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/348.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/348.json
@@ -1 +1 @@
-{"CICLOSPORIN": 6.96783505374988, "GARDASIL": 4.142644689710695, "SUBOXONE": 11.133172099500111, "null": 1.7992031910395463}
\ No newline at end of file
+{"COMBIVIR": 240.005173795878, "null": 0.3708086001093317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3480.json
index 8ea39df2df0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3480.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3480.json
@@ -1 +1 @@
-{"COMIRNATY": 2.3283909617517726, "COVID19": 1.3023994807245385, "IPILIMUMAB": 9.109378620817504, "OMALIZUMAB": 3.940532271061426, "ROACTEMRA": 15.954836955133548, "SHINGRIX": 2.9806985227915392, "SPIKEVAX": 1.000139251878834, "TELMISARTAN": 34.0285107602632, "TOZINAMERAN": 1.3629584752434938, "VAXZEVRIA": 1.1456345311573732, "ZOSTAVAX": 6.616122537711889}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3481.json
index 1d7a4624f80..a72c8a56911 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3481.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3481.json
@@ -1 +1 @@
-{"KAFTRIO": 523.4614025466639}
\ No newline at end of file
+{"ABILIFY": 1.6703569292835023, "BUPRENORPHINE": 79.00426148510387, "CHAMPIX": 2.776768499441, "CYMBALTA": 0.621209353146529, "FENTANYL": 12.014694524199903, "LYRICA": 1.2694030589055516, "OMALIZUMAB": 1.8360896885919924, "PEGASYS": 0.2423683532455524, "PEGINTRON": 1.312083573971311, "PREGABALIN": 4.94861756493467, "SIFROL": 19.03212372873904, "SUBOXONE": 8.94771372074494, "null": 5.8904066428564485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3482.json
index da36c5dbabc..af1696f16f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3482.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3482.json
@@ -1 +1 @@
-{"DULOXETINE": 48.84871061602784, "LEFLUNOMIDE": 172.28820687917533, "SIMPONI": 14.53263905577743}
\ No newline at end of file
+{"OPSUMIT": 17.239014386949403, "null": 0.6597650825628089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3483.json
index 6d068350f34..d6731af906d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3483.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3483.json
@@ -1 +1 @@
-{"null": 1.1662753394176235}
\ No newline at end of file
+{"COMIRNATY": 0.6409101967149414, "VAXZEVRIA": 0.4391374672406169, "null": 0.95118164938859}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3484.json
index 0f4834fcfe0..d048e842f3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3484.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3484.json
@@ -1 +1 @@
-{"AIMOVIG": 1.1165738473491924, "BEVACIZUMAB": 1.5035306440448184, "BRILIQUE": 12.13186677416315, "BRINTELLIX": 1.7063608492039375, "CABOMETYX": 1.3482799163105716, "CHAMPIX": 1.7559644966531731, "CICLOSPORIN": 1.4705312360488725, "CLOPIDOGREL": 8.3446496005831, "COAPROVEL": 1.869785496658949, "EFIENT": 7.418668739802642, "ELIQUIS": 8.81681994686775, "ELTROMBOPAG": 23.818822589702226, "ENOXAPARIN": 3.9827143682713806, "HEMLIBRA": 13.547923342503749, "IBRANCE": 1.1143411158001832, "INCIVO": 2.909971761452355, "INTEGRILIN": 9.913264867442908, "INTRONA": 3.262624305993968, "LEMTRADA": 3.653696064266547, "LENVIMA": 1.653810230931746, "LIXIANA": 16.23723168019448, "NEXAVAR": 3.17010531532471, "NPLATE": 5.727288356321504, "PEGASYS": 3.71265382402777, "PEGINTERFERON": 1.2417372661632369, "PEGINTRON": 3.036156598972957, "PLAVIX": 8.888100807556258, "PRADAXA": 8.706464692511164, "RIBAVIRIN": 1.017392538857917, "SOLIRIS": 1.029408520278368, "STIVARGA": 2.2531532524976754, "SUTENT": 4.027269228774142, "TASIGNA": 1.0284501883988666, "TEMODAL": 2.84944494231234, "TICAGRELOR": 14.890783877736542, "XARELTO": 13.3193976871396, "null": 1.2240176949495292}
\ No newline at end of file
+{"null": 1.9979973112836964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3485.json
index 9f4b27c7eee..ffed2e44063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3485.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3485.json
@@ -1 +1 @@
-{"COVID19": 1.489892598456348, "TOZINAMERAN": 2.172656491762368, "null": 1.1844410043030955}
\ No newline at end of file
+{"null": 0.8953782293383834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3486.json
index 6e71d7a0433..a6808275f11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3486.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3486.json
@@ -1 +1 @@
-{"null": 1.4295803886415972}
\ No newline at end of file
+{"BRINTELLIX": 10.093640961634778, "CELECOXIB": 13.375895333531496, "CHAMPIX": 6.006566643859938, "COMIRNATY": 0.6615426299827996, "CYMBALTA": 1.927568335362972, "KEPPRA": 3.326839077110582, "TOZINAMERAN": 0.5336286120817513, "VAXZEVRIA": 0.2070365074944671, "ZYPREXA": 1.5365665858817013, "null": 3.526992261597321}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3487.json
index 9e5070b0221..c17a881a6e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3487.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3487.json
@@ -1 +1 @@
-{"null": 1.826259048884718}
\ No newline at end of file
+{"null": 2.354342172759579}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3488.json
index a4e41779a7e..a491e7b7428 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3488.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3488.json
@@ -1 +1 @@
-{"SUTENT": 6.065695107302715, "null": 2.3338705466510508}
\ No newline at end of file
+{"null": 2.7765828725675274}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3489.json
index 32608ed7300..c142b5287b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3489.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3489.json
@@ -1 +1 @@
-{"AIMOVIG": 2.522263517015274, "BRIVARACETAM": 47.87628306976799, "CICLOSPORIN": 1.7965872087001622, "ELIQUIS": 1.5431632377394706, "FORSTEO": 2.81331691899648, "HYDROCORTISONE": 30.727243669486285, "IBRANCE": 2.0561398557334174, "KEPPRA": 3.96193335203925, "LEFLUNOMIDE": 31.410858184114343, "PEGASYS": 1.3759875851467047, "SUBOXONE": 2.8142363035856834, "SUTENT": 6.232539746934809, "null": 1.4404577364198394}
\ No newline at end of file
+{"null": 1.395000896118496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/349.json
index 1ad0469688b..7f810b02952 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/349.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/349.json
@@ -1 +1 @@
-{"null": 3.442779540174401}
\ No newline at end of file
+{"CICLOSPORIN": 12.725941366726284, "DEXAMETHASONE": 21.510906939556435, "null": 0.7411877241468018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3490.json
index f720542bafb..53d044ce873 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3490.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3490.json
@@ -1 +1 @@
-{"null": 2.34264995267084}
\ No newline at end of file
+{"ENZALUTAMIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3491.json
index 1a59820296e..b9aa7bcaa4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3491.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3491.json
@@ -1 +1 @@
-{"null": 2.1539091030294992}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3492.json
index 19c062499ae..7bae4d91971 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3492.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3492.json
@@ -1 +1 @@
-{"null": 2.387804269380746}
\ No newline at end of file
+{"ABACAVIR": 0.1859235824489338, "ABASAGLAR": 1.032023338163597, "ABILIFY": 1.7359203524788511, "AERIUS": 1.7988259248217215, "AFINITOR": 0.1294486153470869, "AIMOVIG": 1.3663795955044444, "ALDARA": 1.4729059354181546, "ALISKIREN": 8.56427270464838, "APIDRA": 0.4023929204278664, "APIXABAN": 0.1762184443210052, "ARAVA": 0.0488462332740788, "ARIPIPRAZOLE": 2.124276256381179, "ATAZANAVIR": 0.5565017930153076, "ATRIPLA": 0.1416028786210297, "AUBAGIO": 3.7642857418753017, "AVAMYS": 0.886989216999742, "AZATHIOPRINE": 0.2853332348940731, "BEDAQUILINE": 0.4716400769780521, "BENLYSTA": 1.5960400424154348, "BETAFERON": 2.510332754822995, "BETMIGA": 0.8064520674882997, "BIKTARVY": 2.037233620709862, "BRILIQUE": 0.674081417368984, "BRINTELLIX": 3.3638321426858155, "BRIVARACETAM": 5.250185683210288, "BRIVIACT": 4.787762008082611, "BUPRENORPHINE": 0.9104287964008296, "BYDUREON": 0.451863375308638, "BYETTA": 0.3002404370366702, "CABOTEGRAVIR": 5.637464896256121, "CAPECITABINE": 0.3891262582770765, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3493.json
index 0743e8de7a0..30bafe7bfbd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3493.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3493.json
@@ -1 +1 @@
-{"CELLCEPT": 5.944168645815715, "CICLOSPORIN": 55.07368826719517, "EXFORGE": 20.66609785754913, "KEPPRA": 4.36251703539421, "LEVETIRACETAM": 8.952639175588828, "MYCOPHENOLATE": 11.531704646710814, "null": 2.821325483550392}
\ No newline at end of file
+{"ABACAVIR": 0.3445329154060237, "ABASAGLAR": 0.2551883518310568, "ABATACEPT": 2.260664002139402, "ABILIFY": 2.8074729208309277, "ACETAMINOPHEN/OXYCODONE": 4.811151319976349, "ACLIDINIUM": 0.4902153451801808, "ACTOS": 0.8446423109242325, "ADALIMUMAB": 2.139180965105183, "ADCIRCA": 0.6299325713387164, "AERIUS": 0.3527974963490545, "AFINITOR": 0.3403058151799462, "AGOMELATINE": 7.246560925543954, "AIMOVIG": 1.5896897516062134, "ALDARA": 1.5456304821662965, "ALEMTUZUMAB": 0.1141687795406173, "ALENDRONATE": 7.249656867443968, "ALIMTA": 0.1611033052853034, "ALL": 2.4672795991243306, "ALLI": 3.773920480370724, "AMINOSALICYLIC": 0.7701235751343656, "AMPRENAVIR": 5.2904288142913645, "ANAKINRA": 0.417258583741213, "ANORO": 0.2718761213882196, "APIDRA": 0.3218725418641646, "APIXABAN": 0.6508371025072687, "APREMILAST": 0.5681234808419582, "ARAVA": 0.3218085913283464, "ARIPIPRAZOLE": 1.4863811482566076, "ARSENIC": 3.504193887030684, "ATAZANAVIR": 16.764418731610114, "ATEZOLIZUMAB": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3494.json
index fa904b662b7..e16b09ca7b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3494.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3494.json
@@ -1 +1 @@
-{"null": 1.055977058825828}
\ No newline at end of file
+{"AIMOVIG": 2.5189226955645347, "ARIPIPRAZOLE": 2.7533594409212947, "ATAZANAVIR": 440.7440140627151, "CHAMPIX": 20.72917340619236, "COMIRNATY": 0.1078073583801964, "CYMBALTA": 2.578069007997776, "ENFUVIRTIDE": 188.32462309535268, "KEPPRA": 1.1277200309447035, "SAXENDA": 4.852419087068935, "SPIKEVAX": 0.0659327762696025, "STELARA": 1.1022388268425198, "TOZINAMERAN": 0.3828165922181889, "VAXZEVRIA": 0.1236414762845209, "ZYPREXA": 1.497441968738654, "null": 1.1966886226831903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3495.json
index 9f1fd2274f1..f8a7766f419 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3495.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3495.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0715134335697436, "null": 2.557117244310146}
\ No newline at end of file
+{"ABACAVIR": 2.340914897702409, "ABILIFY": 3.244875834775766, "AMIKACIN": 9.404026951051693, "ARIPIPRAZOLE": 2.8514897581408043, "ATAZANAVIR": 237.29125368986715, "BRINTELLIX": 5.526911880620103, "CHAMPIX": 19.49443370841311, "COMBIVIR": 3.140711009756534, "COMIRNATY": 0.1086533535394024, "CYMBALTA": 2.2086400563131305, "DULOXETINE": 5.463610432885307, "ENFUVIRTIDE": 112.08186894398936, "EPIVIR": 7.813857619497842, "GARDASIL": 0.7217938883396698, "INSULIN": 20.04003398472772, "INTRONA": 15.879332119412894, "ISENTRESS": 11.586861159832932, "KEPPRA": 2.3299272927267687, "LATUDA": 8.108743596904244, "LEVETIRACETAM": 2.2593546973045444, "MEPOLIZUMAB": 5.873194842758486, "NUCALA": 2.383861726131933, "OLANZAPINE": 2.4761380451042783, "PEGASYS": 2.622464177618415, "PEGINTRON": 18.02828028460847, "RIBAVIRIN": 4.092827579778238, "SAXENDA": 5.487649066973128, "VAXZEVRIA": 0.0457153784732469, "ZYPREXA": 2.4368056075384312, "null": 0.8494886096681148}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3496.json
index 91c563c51c3..567cb4c80b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3496.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3496.json
@@ -1 +1 @@
-{"ADALIMUMAB": 4.39560898576439, "AFINITOR": 1.645897040180012, "AIMOVIG": 1.4271093571452858, "CAPECITABINE": 2.724534529343244, "CHAMPIX": 3.854249837068328, "COVID19": 1.5270095199683171, "FORSTEO": 1.661687952544587, "IBRANCE": 2.440842156178432, "INLYTA": 2.2301662877538724, "NEXAVAR": 1.7934441479595036, "PEGASYS": 2.3317856275493303, "RELVAR": 5.894959156646763, "RINVOQ": 6.82892240979074, "SUTENT": 10.84917892171323, "TOVIAZ": 3.49278620452905, "TOZINAMERAN": 1.55163746274794, "XELJANZ": 1.0519441036332764}
\ No newline at end of file
+{"ABILIFY": 2.7874276351386, "BRINTELLIX": 21.688081783999355, "CHAMPIX": 11.78000862654678, "COMIRNATY": 0.680184241887577, "CYMBALTA": 0.9034988353970824, "GARDASIL": 2.5345590122725574, "OLANZAPINE": 2.6921273302930926, "SPIKEVAX": 0.3477495029982069, "TOZINAMERAN": 0.4580748003840734, "VAXZEVRIA": 0.4393467557463162, "null": 2.442899745904828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3497.json
index 7d9d337e884..ee640751074 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3497.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3497.json
@@ -1 +1 @@
-{"null": 1.7833485540510348}
\ No newline at end of file
+{"null": 1.9001059167326195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3498.json
index 5a4719fa6ec..6c228274a9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3498.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3498.json
@@ -1 +1 @@
-{"ATRIPLA": 1.613357635805595, "BUPRENORPHINE": 9.233411682564128, "KEPPRA": 4.559689343370957, "PEGASYS": 1.6962904305852158, "SUTENT": 3.6087781491987703, "null": 1.3850367854157772}
\ No newline at end of file
+{"null": 9.52304895520586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3499.json
index 623fcd87e88..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3499.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3499.json
@@ -1 +1 @@
-{"AFINITOR": 2.7058668508747967, "CHAMPIX": 1.8155690092949568, "CICLOSPORIN": 2.4974080511013823, "EXFORGE": 5.515886743692176, "KEPPRA": 3.1867055273932308, "PEGASYS": 1.1453537150129305, "SUTENT": 6.428414828458981, "TOZINAMERAN": 1.0777572490345777, "XELJANZ": 1.2452191547617264, "null": 1.4099490035205282}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/35.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/35.json
index d58c5713a5b..6dd39f4c8f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/35.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/35.json
@@ -1 +1 @@
-{"COMIRNATY": 4.610774565666639, "SPIKEVAX": 3.0774631601850557}
\ No newline at end of file
+{"CIMZIA": 5.193368855168888, "LANTUS": 4.285590890932472, "STELARA": 9.66384820586531, "null": 1.1126342729690266}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/350.json
index 37db7cb03b8..3d10e40cbce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/350.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/350.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 24.188356581137707, "SUBOXONE": 16.06592616913447, "null": 2.1268714758691285}
\ No newline at end of file
+{"null": 1.006633644640497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3500.json
index 254647a07d2..db4e71915e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3500.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3500.json
@@ -1 +1 @@
-{"null": 1.0043210572211914}
\ No newline at end of file
+{"BUPRENORPHINE": 12.27195316013542, "COMIRNATY": 0.3803116640236785, "ELIQUIS": 1.6004149326545554, "GARDASIL": 2.9716137295692797, "NEXAVAR": 4.526140502652323, "PEGASYS": 2.4183025313187896, "SPIKEVAX": 0.3819473930325042, "TOZINAMERAN": 0.4898083606143548, "VAXZEVRIA": 0.282621501103694, "ZOSTAVAX": 5.703012897835426, "null": 0.8302113112084782}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3501.json
index d1bcc7ec298..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3501.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3501.json
@@ -1 +1 @@
-{"CICLOSPORIN": 175.641602262016}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3502.json
index 5662c45df51..dcc418198b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3502.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3502.json
@@ -1 +1 @@
-{"AFINITOR": 2.7370410412370303, "AIMOVIG": 1.098051079219023, "AUBAGIO": 1.3121701628838025, "BONVIVA": 12.047995164160998, "CHAMPIX": 2.3578315615691428, "COSENTYX": 1.8827766854829884, "EFAVIRENZ": 8.1527815367198, "FORSTEO": 1.0807197562351838, "IBRANCE": 1.817395129709663, "INCIVO": 3.012246640751563, "JANUVIA": 2.160676047524135, "KEPPRA": 1.3207416170990982, "KEYTRUDA": 2.084523558275569, "LENVIMA": 4.872605574255534, "METHOTREXATE": 1.3815839621344608, "PEGASYS": 1.7055534468914422, "PEGINTRON": 1.3832536189425058, "ROACTEMRA": 3.111351241874685, "SIMPONI": 2.525716439120905, "STELARA": 2.7356693109955748, "SUTENT": 2.193372893294227, "XELJANZ": 1.9577774468746785, "null": 1.09575482708816}
\ No newline at end of file
+{"COMIRNATY": 2.4937826409179054, "SPIKEVAX": 8.046009948699199}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3503.json
index 7b9a914e041..3524910608e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3503.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3503.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"null": 1.7675551134348293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3504.json
index f22eb13668d..cc4d670c70a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3504.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3504.json
@@ -1 +1 @@
-{"null": 1.20739048797861}
\ No newline at end of file
+{"null": 2.017202468534504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3505.json
index 64e162d8726..b68652e5ddb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3505.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3505.json
@@ -1 +1 @@
-{"FENTANYL": 10.549928416565864, "null": 1.363694676493956}
\ No newline at end of file
+{"ADALIMUMAB": 0.3009256122263835, "AFINITOR": 0.8954856554981978, "ALDARA": 8.27250449425426, "ALIMTA": 3.3806169212153816, "AMIKACIN": 2.127293656113573, "ARAVA": 0.4651464510564004, "ATRIPLA": 0.0457807161901115, "AUBAGIO": 0.5376131865356842, "AVASTIN": 0.5779585253811962, "AZATHIOPRINE": 1.915840906849727, "BENLYSTA": 0.6676812811633992, "BIKTARVY": 7.072677019060918, "BRAFTOVI": 1.0603867272290346, "BUDESONIDE": 0.2614852271125313, "BUSULFAN": 1.375109314993051, "BYETTA": 0.5634746787619256, "CABOMETYX": 0.8523722195134115, "CAELYX": 3.721657791427838, "CAPECITABINE": 0.9691304362188694, "CETUXIMAB": 7.445992480748502, "CHAMPIX": 0.5931881164406227, "CICLOSPORIN": 0.5764163253024361, "CIMZIA": 0.4591124716576171, "CLOPIDOGREL": 1.4651592103246374, "COMIRNATY": 0.5421138087117046, "COSENTYX": 1.8195644534017508, "COTELLIC": 4.807300347840946, "DOCETAXEL": 0.9138138160126448, "ELIQUIS": 0.3808176950288645, "ENBREL": 1.1881105632358069, "ENTRESTO": 0.4019627839330468, "ENTYVIO": 0.506617730562269, "ERBITUX": 3.5165048428713432, "ERLEADA": 1.985525990512042, "ESBRIET": 1.318953508553655, "EXFORGE": 0.7172782944340212, "FASENRA": 0.9735580837282553, "FASLODEX": 1.019483158516105, "FORSTEO": 0.3641961452106286, "FORXIGA": 0.9624838213805204, "GARDASIL": 0.7723504797332442, "HUMALOG": 0.1616508695190675, "HUMIRA": 0.4680009417176348, "HYDROCORTISONE": 2.194257795647756, "IBRANCE": 0.3569660643668248, "IBUPROFEN": 0.6720162346114389, "ICLUSIG": 1.8396611018466424, "INCIVO": 4.768386329012486, "IPILIMUMAB": 5.697319772514724, "IRESSA": 6.059090348483822, "JANUVIA": 0.7319138525127349, "JARDIANCE": 0.9246404763373532, "KEPPRA": 0.7518876281379764, "KEYTRUDA": 2.192279299806754, "LANTUS": 0.2367950147146276, "LEVOFLOXACIN": 2.5229068639521106, "LIXIANA": 1.456939826019697, "LYRICA": 0.7158663945050293, "MEKINIST": 0.570321595118027, "METFORMIN": 6.073827379398334, "METHOTREXATE": 0.8263007043907181, "MIRVASO": 22.3968792766074, "MMRVAXPRO": 0.7366474242092103, "MODERNA": 0.427819149073296, "NEXAVAR": 3.474368779543348, "NOT": 1.4077148917834643, "NUCALA": 0.4295104421069211, "OLANZAPINE": 0.4165160103271167, "OPDIVO": 4.014861616193892, "OPSUMIT": 0.35519953351416, "OPTIMARK": 3.328776148788992, "PEGASYS": 2.325876806124491, "PEGINTERFERON": 2.563784020374567, "PEGINTRON": 1.7953256999097, "PEMBROLIZUMAB": 3.5903019365419584, "PEMETREXED": 1.899360566687304, "PLAVIX": 0.3495989746193982, "RIBAVIRIN": 3.115985392289459, "RINVOQ": 1.7098961783372726, "ROACTEMRA": 0.9772551627914604, "SHINGRIX": 0.678006418589285, "SIMPONI": 0.5955027021434438, "SPIKEVAX": 0.4279484454251746, "STELARA": 1.2380884113651731, "STIVARGA": 1.3214156384461466, "SUTENT": 0.8400825606088171, "TAGRISSO": 3.8455674481922655, "TASIGNA": 0.8789126929627896, "TEMOZOLOMIDE": 3.528543307937692, "TIVICAY": 4.246830235609122, "TOZINAMERAN": 0.7195084423191622, "TRAMETINIB": 18.482951534780625, "VAXZEVRIA": 0.3272635167922788, "VECTIBIX": 7.49619665145679, "VFEND": 0.595670766840115, "VOTRIENT": 0.9281874799120812, "XELJANZ": 0.3089445491804481, "XOLAIR": 0.9127934167081908, "YERVOY": 2.7726360201119946, "ZELBORAF": 2.226934354910742, "ZOSTAVAX": 3.625455179085625, "ZYPREXA": 0.5389370134085427, "null": 1.508124440767902}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3506.json
index c1122a20f73..fed7b2b580f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3506.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3506.json
@@ -1 +1 @@
-{"ANAKINRA": 1.0465013871518258, "ANORO": 3.4755825787962182, "APIDRA": 2.369939819928134, "AUBAGIO": 1.0572349831661256, "AVAMYS": 5.889531995987892, "AZOPT": 22.032096395214975, "BEOVU": 4.8270793968633, "BETMIGA": 3.0240552842945814, "BIKTARVY": 2.201854598827318, "BYDUREON": 1.5941524661515667, "BYETTA": 1.66307223833574, "CELECOXIB": 11.661514749400643, "CELSENTRI": 18.365198130685133, "CIMZIA": 1.830408102086778, "COAPROVEL": 1.7415686307273135, "COMBIVIR": 1.5751843882039276, "CYMBALTA": 2.682225518826126, "DULAGLUTIDE": 5.539507622759449, "ELIQUIS": 1.7522385484991223, "ENBREL": 1.510419228284246, "EVISTA": 2.0950632273830974, "EXFORGE": 1.8079287799975805, "EYLEA": 5.143838253255844, "FLUTICASONE": 3.829593485783541, "GLYCOPYRRONIUM": 12.489912142733584, "HUMALOG": 7.70953006500159, "INCRUSE": 10.181196200405982, "INSULIN": 1.8762007080734755, "JANUMET": 2.5399464586071274, "JANUVIA": 3.5678032952166734, "LANTUS": 7.999765461225416, "LEVEMIR": 3.941069370397288, "MEPOLIZUMAB": 8.813482547086736, "MICARDIS": 1.085101271414405, "NAGLAZYME": 2.1359201923771782, "NEVANAC": 16.039538818856528, "NUCALA": 3.118923398213462, "RELVAR": 7.038878443668379, "SIMPONI": 1.4756007857781177, "SPRYCEL": 1.0484418327436644, "TASIGNA": 1.0448471531177992, "TOUJEO": 3.3578785022059754, "TOVIAZ": 7.079840221839622, "TRELEGY": 7.702344851887075, "TRULICITY": 1.536407643811229, "VIAGRA": 6.628713638373988, "VICTOZA": 1.334307123777803, "XELJANZ": 2.380241545511129, "ZOSTAVAX": 6.032526246744823, "ZYPREXA": 1.4968745518182374, "null": 1.8812406935638808}
\ No newline at end of file
+{"AFINITOR": 2.1224246565439056, "AVASTIN": 3.6409918643243473, "AZATHIOPRINE": 3.6758627093142175, "BEVACIZUMAB": 7.303255949384154, "BRAFTOVI": 35.456894439896715, "CABOMETYX": 5.1744747029107065, "CETUXIMAB": 121.15455861306222, "COBIMETINIB": 48.64992690740817, "COMIRNATY": 0.2297003592735782, "COTELLIC": 62.81203508210757, "DABRAFENIB": 14.005125160685402, "ELIQUIS": 0.7269951830279144, "ERBITUX": 101.74043409911827, "GEFITINIB": 51.80496949539893, "HERCEPTIN": 4.6161009540491165, "IRESSA": 54.42788815540443, "IRINOTECAN": 29.68723484362347, "KAFTRIO": 13.763802664955474, "KEPPRA": 0.922394550293792, "KEYTRUDA": 1.1804579363472674, "MEKINIST": 17.887616917140672, "NEXAVAR": 2.313862545664453, "PANITUMUMAB": 252.1960532479539, "RINVOQ": 12.647724315834663, "SPIKEVAX": 0.1821402140551016, "SUTENT": 0.990428858300751, "TAGRISSO": 23.26756462073814, "TARCEVA": 109.56520027175364, "TOZINAMERAN": 0.1855538576091253, "TRAMETINIB": 178.3444788149086, "VAXZEVRIA": 0.1363246154940749, "VECTIBIX": 447.14163840948726, "XELJANZ": 0.9009454742760108, "ZELBORAF": 8.024928535082667, "null": 0.4755778471232956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3507.json
index d1be1926e32..59dafc0c113 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3507.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3507.json
@@ -1 +1 @@
-{"null": 1.7112874231168382}
\ No newline at end of file
+{"ACTRAPID": 2.4796739850653986, "ADALIMUMAB": 0.2226678137136283, "AIMOVIG": 0.6271827959644758, "ALIMTA": 0.977433432402278, "APIDRA": 0.9068811502363392, "ARAVA": 0.278531375413844, "ARIXTRA": 5.038670178741249, "AUBAGIO": 0.4942657243675141, "BENLYSTA": 1.066448622259526, "BRILIQUE": 1.2342729620467885, "BRINTELLIX": 0.6509820420901794, "BUDESONIDE": 0.6710205525698169, "BUPRENORPHINE": 0.783413278091187, "CHAMPIX": 1.129610065036204, "CIMZIA": 0.8106185502763735, "CLOPIDOGREL": 1.234060516271796, "COMIRNATY": 0.592872184539651, "COSENTYX": 0.786699654710416, "COTELLIC": 3.560205889772776, "CYMBALTA": 0.1937169966463742, "DEXAMETHASONE": 0.5887164592598824, "DOCETAXEL": 0.8401349825038591, "ELIQUIS": 0.5729725030497248, "ENBREL": 4.666109238538444, "ENOXAPARIN": 1.6396919585562502, "ENTRESTO": 0.962729010000115, "ENTYVIO": 0.839383430745807, "ERLEADA": 2.5803450660117644, "EXJADE": 0.6804966466278469, "FASENRA": 0.820630741079186, "FASLODEX": 0.6279675228050152, "FENTANYL": 0.2344581571517623, "FIASP": 2.431455136177823, "FLUTICASONE": 5.726488059295906, "FORSTEO": 0.3735774278341628, "FORXIGA": 0.5637873892609283, "GARDASIL": 0.6918099051856386, "HUMALOG": 0.3071909569414113, "HUMIRA": 0.5858388843190031, "IBRANCE": 0.3008611042041648, "ICLUSIG": 1.2742156896008283, "INCIVO": 1.041274505262311, "INSULIN": 0.7029930156635198, "INSUMAN": 8.394612998488647, "JANUMET": 0.5382428974953977, "JANUVIA": 1.1297561657207404, "JARDIANCE": 0.8626231615158315, "KAFTRIO": 2.9869741849390783, "KEPPRA": 0.4051431496409208, "KEYTRUDA": 0.3704980887321077, "LACOSAMIDE": 3.1859877651811277, "LANTUS": 0.539316936810701, "LEMTRADA": 1.2894360454042784, "LEVEMIR": 2.032898520053178, "LEVETIRACETAM": 2.295182024544755, "LEVOFLOXACIN": 2.4472770576227223, "LIXIANA": 2.287985239180357, "MEPOLIZUMAB": 5.747382619444923, "METHOTREXATE": 0.3463007103215281, "MICARDIS": 0.7695398020425954, "MIDAZOLAM": 3.119975391255279, "MMRVAXPRO": 1.620775716179209, "MODERNA": 1.3774493730923278, "NEXAVAR": 1.2114852957987965, "NIMENRIX": 1.0886022792345138, "NOVORAPID": 0.5946154819391525, "NUCALA": 1.8827237069811436, "OLANZAPINE": 0.5318797519007762, "ONCASPAR": 2.3680730845568143, "PEGASYS": 0.5580002278964769, "PEGINTRON": 0.4691328440986866, "PLAVIX": 0.80759030275048, "PLEGRIDY": 1.1318385446060777, "PRIVIGEN": 3.2309701505256028, "RINVOQ": 0.8241605143310754, "ROACTEMRA": 0.8236882031545358, "ROTATEQ": 1.7081849868130443, "SAXENDA": 1.9039949732014063, "SHINGRIX": 0.9665564316079992, "SIMPONI": 1.3437579271393143, "SPIKEVAX": 0.5187198629975216, "STELARA": 0.701526901574367, "STIVARGA": 0.9917631817440072, "SUTENT": 0.2951836613501016, "TAMIFLU": 2.201679330322688, "TASIGNA": 0.4988489518610857, "TICAGRELOR": 1.5714380874033682, "TOUJEO": 1.30619119238236, "TOZINAMERAN": 0.5525732431418654, "TRIUMEQ": 3.777233281008909, "TRULICITY": 0.8271798116448433, "TWINRIX": 2.642929518840741, "VAXZEVRIA": 0.4665842525168165, "VICTOZA": 0.6137672966167041, "VIMPAT": 1.4639058767305673, "XELJANZ": 0.204236085556801, "XOLAIR": 0.4507546075199755, "ZOSTAVAX": 0.3683552216238971, "ZYPREXA": 1.0602716848788756, "null": 2.005906404376337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3508.json
index 55191d3d37d..f3f17c0cb7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3508.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3508.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 12.391755044734383, "ELIQUIS": 2.32722122478057, "KEPPRA": 13.13220802569392, "STELARA": 4.795264726169499, "TEMODAL": 118.01532593067084, "TEMOZOLOMIDE": 355.40828063677634}
\ No newline at end of file
+{"ACLIDINIUM": 92.34949312126048, "ARIPIPRAZOLE": 7.037381065753245, "CICLOSPORIN": 3.6786033796050286, "COMIRNATY": 1.0522721175186842, "COSENTYX": 2.1908940939854897, "DUPILUMAB": 151.26746399987078, "DUPIXENT": 59.5831003354255, "EPADERM": 403.043666715322, "FLUTICASONE": 29.91756489879539, "GARDASIL": 1.6232685772812907, "HYDROCORTISONE": 6.322674944080609, "INFANRIX": 28.100623535048165, "JANUMET": 1.7009756862208012, "METHOTREXATE": 3.0124799840655734, "MMRVAXPRO": 4.177515936600098, "PROTOPIC": 111.62323705997188, "RINVOQ": 74.41847015510488, "ROTATEQ": 7.809937662654876, "SPIKEVAX": 0.5484699342158691, "STELARA": 1.715484317168809, "SUBOXONE": 1.3383134328343325, "TOZINAMERAN": 0.8663812262922558, "TREMFYA": 4.440725754656199, "UPADACITINIB": 63.92018175252005, "VAXZEVRIA": 0.3380345972518865, "XOLAIR": 6.10030137690918, "ZOSTAVAX": 2.609680949464652, "null": 0.6862307600590091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3509.json
index df1a136927c..6e89dc16f52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3509.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3509.json
@@ -1 +1 @@
-{"ASPARAGINASE": 76.12593055161321, "KEPPRA": 14.24832925259962, "TEMODAL": 115.32368295869314, "TEMOZOLOMIDE": 250.3005974242701}
\ No newline at end of file
+{"ADENURIC": 6.512396466399284, "AERIUS": 5.254148823013673, "ALIMTA": 3.992593480382662, "ARAVA": 0.2891515331448361, "BUDESONIDE": 0.6498666769453113, "BUMETANIDE": 4.744126625006627, "BUSILVEX": 12.529835505686144, "BUSULFAN": 1.3676700455828767, "CAELYX": 6.755571905295695, "CHAMPIX": 0.679117546677276, "CICLOSPORIN": 0.282810062560775, "CIMZIA": 0.2252575250485316, "CLOPIDOGREL": 0.8958412769348132, "COAPROVEL": 3.171529658204246, "COMIRNATY": 0.3352174638700503, "CYMBALTA": 0.5407664063434356, "DEXAMETHASONE": 0.7371886539526291, "ELIQUIS": 0.3444739521373048, "EMEND": 21.364570214093018, "ENOXAPARIN": 9.50495150725252, "ENTRESTO": 0.4896036796941042, "EUCREAS": 24.383506259140844, "FORXIGA": 1.1435471634337482, "GALVUS": 23.033626864547927, "GARDASIL": 0.2700074110088373, "HYDROCORTISONE": 2.773415192374344, "IBUPROFEN": 1.2266461205900223, "INCIVO": 3.1527492325868445, "JANUMET": 0.8971321950050857, "JANUVIA": 2.0711471658524383, "JARDIANCE": 0.5032527019917014, "KEPPRA": 1.2909385435730425, "KEYTRUDA": 1.979749346796128, "LEVOFLOXACIN": 1.5427211039268975, "LYRICA": 1.1049875931819535, "METFORMIN": 9.986265913816217, "MMRVAXPRO": 0.7964263019437658, "NEXAVAR": 3.4760071191104784, "OLANZAPINE": 0.484255656247654, "OLYSIO": 4.730784363599918, "OPDIVO": 1.7352593866114283, "PEGASYS": 0.7707044225089069, "PEGINTERFERON": 1.3670621900937427, "PEGINTRON": 0.381739487802409, "PEMBROLIZUMAB": 3.483598648842467, "PLAVIX": 1.2495488520731997, "PROTELOS": 7.295777580713275, "RASILEZ": 2.6820779592674424, "ROACTEMRA": 0.8271820958742846, "SHINGRIX": 1.976167456613904, "SIMPONI": 1.2628934962981309, "SPIKEVAX": 0.2329482954537067, "STELARA": 0.4698356779126709, "STIVARGA": 2.726403222348529, "SUTENT": 0.4564530607832717, "TAMIFLU": 2.2472244374861376, "TOZINAMERAN": 0.2265048252540904, "VAXZEVRIA": 0.21771350470102, "VFEND": 3.936563750137501, "VORICONAZOLE": 3.087547490244901, "XARELTO": 2.135694196566929, "ZELBORAF": 4.259977937268271, "ZOSTAVAX": 0.7241323545760979, "null": 2.4483902985308186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/351.json
index cfb26bc642b..92b0750930f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/351.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/351.json
@@ -1 +1 @@
-{"null": 1.7115280359095626}
\ No newline at end of file
+{"ATRIPLA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3510.json
index 0f0e58414c3..efc7b4a703a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3510.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3510.json
@@ -1 +1 @@
-{"KEPPRA": 10.192927219759229, "MEKINIST": 40.09074554321754}
\ No newline at end of file
+{"ABILIFY": 1.101889050831659, "BUDESONIDE": 1.5938999059573022, "BUPRENORPHINE": 2.0768509966574698, "COMIRNATY": 0.2250449010306781, "COSENTYX": 0.6763458439624477, "DEXAMETHASONE": 0.9463171575491708, "EVRA": 17.97830950180935, "GARDASIL": 1.4181978016312842, "IBUPROFEN": 1.5080062252160653, "METHOTREXATE": 0.9906013001408056, "MIRVASO": 68.41485373281414, "NOT": 4.870256629086287, "OLANZAPINE": 0.8568985814821883, "OMALIZUMAB": 12.252395812444208, "OPSUMIT": 5.437216853586865, "PEGASYS": 0.3146304551755734, "PEGINTRON": 0.6673365889010012, "RENVELA": 352.636519738192, "REVATIO": 3.349191792504342, "SPIKEVAX": 0.1193719051708894, "TOZINAMERAN": 0.4346899105416858, "VAXZEVRIA": 0.0490971151857211, "ZOSTAVAX": 7.734241979972682, "null": 3.558179498539181}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3511.json
index 958942651d2..f5c0b85baaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3511.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3511.json
@@ -1 +1 @@
-{"null": 1.4952445862083286}
\ No newline at end of file
+{"ROTATEQ": 51.23444185689549, "SYNAGIS": 38.7021861099303, "null": 2.1428888712932923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3512.json
index 5bda63a0ce1..35a02c38a47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3512.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3512.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 138.21192701213536, "FENTANYL": 26.93083447647913}
\ No newline at end of file
+{"ATRIPLA": 0.3564673355028256, "CLOPIDOGREL": 2.5007704179056267, "COSENTYX": 1.4153730513168277, "ERLEADA": 12.692730411205076, "IBUPROFEN": 3.088083754021449, "ICLUSIG": 16.309643829841363, "JANUVIA": 3.1637372916046536, "KEPPRA": 2.302156436116518, "KEYTRUDA": 1.2474411225325868, "LAMIVUDINE": 8.587223678650858, "LANTUS": 0.6072825799519386, "LEVOFLOXACIN": 2.6691112001115385, "NEXAVAR": 3.940516452845788, "PEGASYS": 1.175655308926402, "PLAVIX": 2.6210137666855515, "STELARA": 3.614521409408253, "STIVARGA": 3.8163338805428335, "VFEND": 6.396929270622333, "VORICONAZOLE": 6.540864814234395, "null": 2.7291185244407137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3513.json
index 4f20e1e3044..41a35e0747d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3513.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3513.json
@@ -1 +1 @@
-{"ATRIPLA": 29.376490636131688, "ELIQUIS": 1.1230156726965443, "ENTRESTO": 4.997079519827066, "FORXIGA": 6.56700836661905, "HUMIRA": 3.759555549185874, "JARDIANCE": 8.889983646381813, "KALETRA": 6.550554786667801, "STRIBILD": 19.99977407824438, "TRUVADA": 34.19553337255382, "VIREAD": 8.336870075297226}
\ No newline at end of file
+{"ADALIMUMAB": 0.3920159692667948, "ADENURIC": 7.671345391503486, "ALIMTA": 2.545215994788846, "AMIKACIN": 5.746425597486221, "APROVEL": 5.290564489023077, "BRILIQUE": 1.515050279275836, "CAELYX": 2.9702628391934014, "CANCIDAS": 13.350111919498111, "CICLOSPORIN": 3.26704726002219, "CLOPIDOGREL": 1.122428629946355, "COMIRNATY": 0.0851933951670755, "COSENTYX": 4.551636072753065, "CUBICIN": 4.468505202781701, "DESLORATADINE": 7.623199009910531, "DEXAMETHASONE": 1.1494030587185944, "ELIQUIS": 0.2435870275125228, "EMEND": 6.2066133312875165, "ERLEADA": 15.82085825707848, "FENTANYL": 1.6118008631033662, "HUMIRA": 2.269502091835325, "IBUPROFEN": 2.3934449847342383, "INCIVO": 5.134749339016444, "ISENTRESS": 3.795039406519604, "JANUVIA": 0.9595455511053116, "KEPPRA": 0.9252153190347568, "KEYTRUDA": 0.5446919617926538, "LEVEMIR": 1.6561586552044252, "LEVETIRACETAM": 1.1519000523927552, "MABTHERA": 5.151369433240756, "METHOTREXATE": 3.622678885237523, "MICARDIS": 2.99142010022471, "NEXAVAR": 1.5808245222932258, "OPDIVO": 1.7057489627634812, "PEGASYS": 0.4423437649508546, "PEGINTRON": 1.671672129202662, "PLAVIX": 3.0302036058567574, "PRIVIGEN": 2.019778522512849, "RINVOQ": 1.634427612736493, "SKYRIZI": 7.177791313020195, "SPIKEVAX": 0.0648492148158624, "STELARA": 3.7210284104255726, "STIVARGA": 3.2921134231959983, "TAMIFLU": 1.0977222819307466, "TOZINAMERAN": 0.065830877360162, "TREMFYA": 2.199150991812561, "VAXZEVRIA": 0.054828938780998, "VFEND": 5.70596912895872, "ZELBORAF": 9.615550492607357, "null": 2.847284208839198}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3514.json
index a4c11a9049e..318a4520c6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3514.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3514.json
@@ -1 +1 @@
-{"ABACAVIR": 1.0865611458922164, "AFINITOR": 2.012363621273318, "ALPELISIB": 8.32963304444604, "ARIPIPRAZOLE": 2.990640585915975, "ATAZANAVIR": 3.497584496241336, "ATRIPLA": 4.8327112381646975, "BIKTARVY": 10.884422190208015, "BUMETANIDE": 5.943983092291953, "BYDUREON": 1.2945878312985184, "BYETTA": 1.339255004579943, "CICLOSPORIN": 3.0128829487803674, "CLOPIDOGREL": 1.80149182092632, "CUBICIN": 1.85377516161719, "DAPAGLIFLOZIN": 8.49638488109364, "EDURANT": 27.643554080405792, "ELIQUIS": 1.3557246022249934, "EMPAGLIFLOZIN": 11.458758221066695, "EMTRICITABINE": 11.217394176131512, "ENTRESTO": 35.55669847920228, "EPCLUSA": 5.476512084250556, "EXFORGE": 1.6759591669513356, "EXJADE": 5.954876076476644, "FORXIGA": 40.43731938826015, "FULVESTRANT": 2.3858953826322846, "GALAFOLD": 21.12201785750508, "GENVOYA": 11.564132450969906, "HARVONI": 9.59118611304434, "HEPSERA": 9.909123720359222, "HUMIRA": 1.262579061046095, "INCIVO": 1.0046085575652677, "INSULIN": 1.4625061095095224, "IVABRADINE": 26.640445622249874, "JAKAVI": 2.7396190427469653, "JANUMET": 1.1713190713072714, "JANUVIA": 1.4688601935296977, "JARDIANCE": 17.19735007123964, "KISQALI": 2.372394845257269, "KYMRIAH": 1.5709820165824904, "LIXIANA": 5.076442554601303, "LUPKYNIS": 54.10652661597313, "LYNPARZA": 3.351891295247144, "METFORMIN": 3.82382876781628, "MICARDIS": 1.0109358645821125, "MULTAQ": 10.712231050801597, "PEGINTERFERON": 2.972268343849347, "PEMETREXED": 2.3813590387932786, "RANEXA": 6.02218835659011, "RASILEZ": 14.738760835681012, "REBETOL": 3.2845716783947854, "REMDESIVIR": 14.186033443450928, "REYATAZ": 4.208226432560288, "RUBRACA": 4.193727772477089, "SAMSCA": 10.993233127056232, "SOLIRIS": 2.4117230144325097, "SOVALDI": 4.504709760160125, "SPIRONOLACTONE": 3.442983425662264, "STRIBILD": 7.059146965188791, "TASIGNA": 1.2886076481744622, "TENOFOVIR": 26.25382620265648, "TIVICAY": 4.202684904602609, "TRULICITY": 4.345697265948747, "TRUVADA": 5.544934713583113, "VALSARTAN": 12.168385066272046, "VICTOZA": 1.2813421173900297, "VIREAD": 7.780712543780693, "XARELTO": 1.9222208599925448}
\ No newline at end of file
+{"COMIRNATY": 1.0036462260213423, "null": 0.8456583730804215}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3515.json
index f457a9e697a..9bd66f37814 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3515.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3515.json
@@ -1 +1 @@
-{"ATRIPLA": 9.139097611744242, "DAPAGLIFLOZIN": 115.4869166457034, "ENTRESTO": 9.25722964247403, "JARDIANCE": 10.052622838322598, "STRIBILD": 11.120092820898366, "TRUVADA": 19.96672116034269}
\ No newline at end of file
+{"COMIRNATY": 0.3262828045262205, "EMEND": 188.61368844580625, "PEGASYS": 7.027374826211197, "null": 0.5756435642799149}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3516.json
index fc979b80a41..e22b6ca94cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3516.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3516.json
@@ -1 +1 @@
-{"SPIKEVAX": 16.29216072354908}
\ No newline at end of file
+{"ARAVA": 3.659225761321351, "CIMZIA": 5.964164782131716, "COMIRNATY": 0.4376930207057987, "COSENTYX": 10.66869948256928, "KEYTRUDA": 7.0738523044524655, "NEXAVAR": 2.076956033137758, "OPDIVO": 6.18950933479755, "PEGASYS": 1.2789885932940588, "SIMPONI": 12.319920637487035, "SPIKEVAX": 0.1181178422376878, "STELARA": 2.211241540140405, "VAXZEVRIA": 0.1013655798611734, "null": 0.6405233023404333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3517.json
index 4680b1ed4fb..9915cc1b2d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3517.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3517.json
@@ -1 +1 @@
-{"CICLOSPORIN": 39.54997060207162}
\ No newline at end of file
+{"COMIRNATY": 0.6281912240617372, "ZOSTAVAX": 55.37177428498204, "null": 0.615693699682771}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3518.json
index d46aa678a2b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3518.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3518.json
@@ -1 +1 @@
-{"CELLCEPT": 3.097694837447677, "CICLOSPORIN": 5.575496494992393, "IPILIMUMAB": 11.684935902526489, "KEYTRUDA": 1.7919263071007332, "SIMPONI": 4.575109649725683, "SOLIRIS": 4.517016546393328, "null": 1.0636115083549431}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3519.json
index cdf82677fe3..4abdd7ea39c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3519.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3519.json
@@ -1 +1 @@
-{"CUBICIN": 80.43272265657906}
\ No newline at end of file
+{"PAZOPANIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/352.json
index a76a7eec579..49b1b7b1a37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/352.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/352.json
@@ -1 +1 @@
-{"null": 2.5907254632306738}
\ No newline at end of file
+{"null": 0.5469400070995776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3520.json
index fddc1fbacac..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3520.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3520.json
@@ -1 +1 @@
-{"null": 1.0746098492797225}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3521.json
index 58cc8e26866..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3521.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3521.json
@@ -1 +1 @@
-{"CELLCEPT": 14.06277910495802, "CICLOSPORIN": 11.342496122696632, "SOLIRIS": 30.24916690227435}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3522.json
index 96b5c1e9fd7..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3522.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3522.json
@@ -1 +1 @@
-{"ATRIPLA": 1.21267974507905, "BUSULFAN": 25.566605341903905, "CELLCEPT": 6.091074106028458, "CICLOSPORIN": 15.394041420367198, "IBUPROFEN": 7.458796376711299, "KEYTRUDA": 3.1839275060083363}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3523.json
index 828430ae5fc..16bd1555e44 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3523.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3523.json
@@ -1 +1 @@
-{"ATRIPLA": 1.4853287293521291, "CICLOSPORIN": 20.206974824428503, "COMIRNATY": 1.0108270887427335, "SPIKEVAX": 1.042524459325504, "TOZINAMERAN": 4.63559820657885}
\ No newline at end of file
+{"CELLCEPT": 3.874459558840495, "CICLOSPORIN": 3.5681805344960216, "COMIRNATY": 0.7235628759348509, "CYMBALTA": 2.7291637287675385, "FAMPYRA": 8.366307068445371, "GARDASIL": 2.425912937723406, "HUMAN": 9.957327503069898, "KEYTRUDA": 8.576905071653554, "PEGASYS": 1.00006277120715, "SPIKEVAX": 0.3701898005780468, "TOZINAMERAN": 2.0359506370563034, "VAXZEVRIA": 0.2558695275764031, "XELJANZ": 2.662911599935046, "null": 0.934154712162804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3524.json
index ac1c162a50a..6b5b078f4dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3524.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3524.json
@@ -1 +1 @@
-{"null": 1.119713475861358}
\ No newline at end of file
+{"null": 0.6208268902655495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3525.json
index a6785421033..ebbd24c9914 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3525.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3525.json
@@ -1 +1 @@
-{"KEYTRUDA": 5.415055326807208, "SIMPONI": 6.484344762149149, "TOZINAMERAN": 1.3783003162332572, "null": 1.3979719557700496}
\ No newline at end of file
+{"null": 0.8325925131434914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3526.json
index c68f95372fa..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3526.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3526.json
@@ -1 +1 @@
-{"CICLOSPORIN": 40.862364270202725}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3527.json
index 6871292b46e..806b7e3f8a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3527.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3527.json
@@ -1 +1 @@
-{"BASILIXIMAB": 151.73728268961497, "CICLOSPORIN": 30.55514831674318, "SOLIRIS": 14.076968450905982, "null": 1.117567638645243}
\ No newline at end of file
+{"COMIRNATY": 0.5181523752111796, "SPIKEVAX": 0.3506999366549651, "null": 1.1925556625250218}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3528.json
index 10f92c76ff2..62ef74ee3be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3528.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3528.json
@@ -1 +1 @@
-{"CHAMPIX": 2.463127733345117, "COSENTYX": 1.8680950477674865, "INLYTA": 4.033188573388499, "IRESSA": 7.513602512433928, "KEYTRUDA": 1.6335028631017372, "NEXAVAR": 2.618656485935144, "PEGASYS": 1.1460043907836286, "PEGINTRON": 1.9876408924373528, "STIVARGA": 2.8679538698210845, "SUTENT": 5.440170499191932, "null": 2.2492331093831672}
\ No newline at end of file
+{"ALIMTA": 41.13463772213367, "COMIRNATY": 0.2443704599224007, "ROACTEMRA": 46.80242353051369, "SPIKEVAX": 0.513979116267368, "null": 1.2610109582776048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3529.json
index b8ff685a995..b74b7275f26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3529.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3529.json
@@ -1 +1 @@
-{"ABATACEPT": 12.550991274823414, "ACETAMINOPHEN": 26.077630807602503, "ADALIMUMAB": 25.241274263524, "AMINOSALICYLIC": 1.180698046079092, "APREMILAST": 5.044314927048245, "APREPITANT": 31.26092587474628, "ARAVA": 47.29144898429404, "CERTOLIZUMAB": 7.101370809522758, "CIMZIA": 3.538847448953307, "ERELZI": 4.241965368332411, "INLYTA": 1.2879185217479745, "RITUXIMAB": 1.780996775171939, "SUTENT": 3.873448485935104}
\ No newline at end of file
+{"CELLCEPT": 28.649251966705613, "OMALIZUMAB": 42.58544353536453, "null": 0.8914085045646701}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/353.json
index 090493b44a5..fdf26b708d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/353.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/353.json
@@ -1 +1 @@
-{"ABILIFY": 19.97850996290246, "FENTANYL": 104.61975909858396, "null": 1.4748266597185058}
\ No newline at end of file
+{"null": 2.062370356223864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3530.json
index f6af0016f37..5f252248831 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3530.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3530.json
@@ -1 +1 @@
-{"FENTANYL": 13.44333609696427, "null": 4.767900239223762}
\ No newline at end of file
+{"NEXAVAR": 31.28700167329784, "null": 1.1208565609491865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3531.json
index b1c3895e5d6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3531.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3531.json
@@ -1 +1 @@
-{"IPILIMUMAB": 93.33687687709478, "KEYTRUDA": 29.36680594561123, "OPDIVO": 27.08891849697116}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3532.json
index 128bbf04922..8710c7865a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3532.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3532.json
@@ -1 +1 @@
-{"null": 1.6317463676500423}
\ No newline at end of file
+{"CAELYX": 354.2972950340737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3533.json
index 096650220cd..3346612803b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3533.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3533.json
@@ -1 +1 @@
-{"ABACAVIR": 5.069443730099772, "ABILIFY": 4.60899047970853, "AFINITOR": 3.191880854662179, "ANAKINRA": 22.199137176182617, "AZATHIOPRINE": 3.7614694105568063, "CHAMPIX": 1.1035543943181652, "CICLOSPORIN": 1.916519071400616, "CIMZIA": 1.0859872059657198, "CYMBALTA": 1.493112255773395, "GARDASIL": 1.4952724899757377, "HUMIRA": 6.6923583982254105, "NUCALA": 3.803117986316304, "OLANZAPINE": 1.842544168889535, "PASIREOTIDE": 115.57485983627264, "PLAVIX": 1.4267004206274274, "SOMATROPIN": 68.31341766630216, "TASIGNA": 3.8883943644847903, "ZOSTAVAX": 17.75243995811166, "ZYPREXA": 15.224548656496314, "null": 1.3283218551258946}
\ No newline at end of file
+{"AVASTIN": 17.910735588289313, "BEOVU": 410.9126513395976, "BRAFTOVI": 80.95807066782193, "BROLUCIZUMAB": 498.59283968601534, "EYLEA": 372.9170308702866, "null": 0.4156994654466748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3534.json
index f5b90200fdd..e685f526144 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3534.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3534.json
@@ -1 +1 @@
-{"JARDIANCE": 28.11855533488308, "null": 1.0715236592738056}
\ No newline at end of file
+{"SUBOXONE": 86.20751176039343, "null": 1.4222406042429754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3535.json
index eb1a9fdacc8..7bf0f4e6123 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3535.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3535.json
@@ -1 +1 @@
-{"CYMBALTA": 5.748010044858063, "FORXIGA": 51.36101939593361, "HEPSERA": 100.6072620648826, "JARDIANCE": 45.55519758398425, "OLANZAPINE": 4.372717211170411, "SUTENT": 1.2456652895653983, "ZYPREXA": 4.557271525088346}
\ No newline at end of file
+{"null": 12.608758045844272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3536.json
index 0ed9deb15fe..afe9487f70b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3536.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3536.json
@@ -1 +1 @@
-{"FASTURTEC": 995.870006735314, "HUMALOG": 95.23771580825802}
\ No newline at end of file
+{"BUPRENORPHINE": 14.494053851764043, "COMBIVIR": 3.5677303928096813, "CYMBALTA": 0.6362187492452624, "EMTRICITABINE": 6.819118949958146, "EPIVIR": 8.526011797102349, "FENTANYL": 2.8700431251354317, "IBUPROFEN": 1.2992845582833967, "INFANRIX": 31.41941235395304, "KALETRA": 4.217324340648887, "KEPPRA": 5.957345731846353, "LACOSAMIDE": 4.733372050473918, "LAMIVUDINE": 9.99744183568796, "LEVETIRACETAM": 5.286067221187848, "MMRVAXPRO": 1.6695423722856608, "NEVIRAPINE": 17.129683266356256, "PREVENAR": 8.439592604134354, "ROTATEQ": 2.6792810252565418, "SUBOXONE": 7.58536031568013, "SYNAGIS": 3.5914138891307537, "VIMPAT": 4.750528823758352, "null": 6.387545845501897}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3537.json
index 7450339a667..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3537.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3537.json
@@ -1 +1 @@
-{"ZYPREXA": 22.79795703353525, "null": 1.7046058036911742}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3538.json
index b040d43ecd8..030666f2ec4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3538.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3538.json
@@ -1 +1 @@
-{"CYMBALTA": 9.200053484662345, "GARDASIL": 16.407748403799914, "null": 2.0451769405011837}
\ No newline at end of file
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3539.json
index d79a6e2b604..77c47af313f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3539.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3539.json
@@ -1 +1 @@
-{"ABACAVIR": 3.383961996854826, "ATRIPLA": 4.516974126708405, "BUSULFAN": 7.056713035265832, "EMTRICITABINE": 38.58930676135778, "EXJADE": 15.03759326325902, "FORXIGA": 49.744970889524495, "HEPSERA": 47.59055984878525, "JARDIANCE": 25.42934990386668, "KALETRA": 7.481035001476095, "LOPINAVIR": 35.58593287566713, "NORVIR": 13.658677211931511, "TENOFOVIR": 208.0560519742387, "TRUVADA": 5.991290921759968, "VIREAD": 46.00087635976696, "ZYPREXA": 11.715524148597604}
\ No newline at end of file
+{"ASPARAGINASE": 49.03196797447769, "LEVETIRACETAM": 17.14280969596731, "SUBOXONE": 7.320066583805854, "null": 2.4242000894971256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/354.json
index 35032404d77..6c4df1799c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/354.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/354.json
@@ -1 +1 @@
-{"GARDASIL": 145.51225347647076}
\ No newline at end of file
+{"ABATACEPT": 2.347908264423284, "ABILIFY": 3.5330031053492226, "ADALIMUMAB": 7.106945460347239, "AIMOVIG": 0.9653241786089116, "ALIMTA": 0.6924757625352441, "AMIKACIN": 1.6640227999602248, "AMINOSALICYLIC": 6.645147571515391, "ANAKINRA": 1.06682486328893, "ANORO": 1.5921662471781537, "APIDRA": 0.4562582142465419, "APIXABAN": 3.930474957149952, "APREMILAST": 21.84387452660102, "ARANESP": 0.7680679161641768, "ARAVA": 4.650827003170269, "ARIPIPRAZOLE": 2.172790258980814, "ATRIPLA": 0.0453670547958752, "AUBAGIO": 0.9995501699145808, "AVANDIA": 0.288675946047095, "AVONEX": 5.390946362171228, "AZATHIOPRINE": 0.6356837176946467, "BENLYSTA": 3.0537326151522164, "BRINTELLIX": 1.4673999850970891, "BRIVARACETAM": 7.406526535955066, "BRIVIACT": 7.657926244819743, "BUDESONIDE": 4.84343170454478, "BUPIVACAINE": 3.1648886767878404, "BUPRENORPHINE": 0.746759450202772, "BYDUREON": 0.4195753318335843, "BYETTA": 1.1302929148870713, "CABOMETYX": 1.2759116714615824, "CARDIAC": 158.68681068071453, "CELECOXIB": 1.5799550389821329, "CICLOSPORIN": 0.2176118306743252, "CIMZIA": 3.355590098400398, "CLOPIDOGREL": 0.2688173465401629, "COMIRNATY": 0.0344363312273144, "COSENTYX": 1.5658265470436366, "CYMBALTA": 0.490742965930297, "CYTARABINE": 0.3124191370456932, "DARUNAVIR": 2.4673071989557864, "DARZALEX": 1.8106291644460832, "DEXAMETHASONE": 0.989790160154676, "DULOXETINE": 1.327826689383352, "ELIQUIS": 0.3847188794239161, "ENBREL": 5.67063554754995, "ENTRESTO": 0.4403494456369616, "ENTYVIO": 2.818736795473397, "EYLEA": 0.5513805668785896, "FASENRA": 1.2232873604963894, "FASLODEX": 1.3851832882009558, "FENTANYL": 1.804817090783225, "GARDASIL": 1.3476760028402963, "HIZENTRA": 1.1749058781513668, "HUMALOG": 0.4633520790685209, "HUMAN": 0.9293108059927396, "HUMIRA": 5.29476085376285, "HYDROCORTISONE": 1.5490300178419851, "IBUPROFEN": 0.3899360306161432, "INCRUSE": 3.8641377412606337, "INTUNIV": 46.95851037294072, "INVEGA": 4.44714800354435, "ISENTRESS": 1.7938201856260485, "JANUMET": 1.0525614354170374, "JANUVIA": 0.9461882638713704, "JARDIANCE": 0.1891919660539067, "KEPPRA": 4.460199161785076, "KEYTRUDA": 1.1070546501989134, "KIOVIG": 1.7506174176660985, "LACOSAMIDE": 1.6648235477501816, "LANTUS": 0.3321808629019182, "LEFLUNOMIDE": 2.200835674183809, "LEVETIRACETAM": 2.524222450790091, "LEVOFLOXACIN": 0.4908905735645489, "LUMYKRAS": 15.624488438250165, "LYNPARZA": 2.215978195521097, "LYRICA": 1.2667051101204256, "MEKINIST": 1.025863922209325, "MEPOLIZUMAB": 5.995506027628534, "METHOTREXATE": 0.4830096758573988, "NEULASTA": 3.011316265978972, "NEXAVAR": 1.3907776157671197, "NINLARO": 3.734081652832816, "NOT": 1.2593476221542006, "NPLATE": 1.7220628652619168, "NUCALA": 3.6050401888107575, "OLANZAPINE": 1.435040741856768, "OPDIVO": 0.9486368684746586, "OPSUMIT": 0.4993372822902022, "OXYBUTYNIN": 2.7218198777741502, "PEGASYS": 0.5257862967569933, "PEGINTERFERON": 0.749402445825356, "PEGINTRON": 0.370275505402636, "PIRFENIDONE": 21.581837887027127, "PLAVIX": 0.2468320020570194, "PREGABALIN": 1.381759049512579, "REMICADE": 2.345376446178961, "REVLIMID": 2.1119849409742666, "RIBAVIRIN": 0.8680183157565562, "RINVOQ": 4.115643075660525, "RISPERIDONE": 3.012132011989039, "RITUXIMAB": 0.3898693324479582, "RUBRACA": 2.6676802329273364, "SAXENDA": 0.6131520704857547, "SHINGRIX": 0.2798461109286795, "SIMPONI": 2.1045104928881324, "SOLIRIS": 0.4462783426380147, "SPIKEVAX": 0.1441032821329241, "SPRYCEL": 0.7460930233957009, "STELARA": 1.0757678502970347, "STIVARGA": 1.458441100661591, "SUBOXONE": 0.6544268562383527, "SUTENT": 0.0888392571083677, "TOZINAMERAN": 0.0515241504465821, "TRELEGY": 1.5529487620433668, "VAXZEVRIA": 0.175291787881851, "VIMPAT": 1.9656226595034405, "VOTRIENT": 4.670840317891651, "XARELTO": 1.1891445305112274, "XOLAIR": 0.5358467888522149, "XTANDI": 1.2056413524641063, "XYREM": 2.341548170670347, "ZEJULA": 8.89652211482779, "ZOSTAVAX": 1.3394891483072529, "ZYPREXA": 0.2722460789884435, "null": 1.1145065976625803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3540.json
index cd63d667548..5322c478f87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3540.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3540.json
@@ -1 +1 @@
-{"JARDIANCE": 26.479544845359836}
\ No newline at end of file
+{"null": 2.467032793883158}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3541.json
index 6c580d60080..ac64150475d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3541.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3541.json
@@ -1 +1 @@
-{"BYDUREON": 9.81137658882837, "FORXIGA": 16.319198488376887, "HUMALOG": 9.749623360669291, "INSULIN": 8.60139676029587, "JANUMET": 24.983585131862306, "JANUVIA": 15.958974386412882, "JARDIANCE": 35.01544088471152, "LANTUS": 19.278732903068644, "LEVEMIR": 18.28899499981921, "NOVORAPID": 10.467937207372954, "TOUJEO": 26.25361228980562, "TRULICITY": 14.252844878612102, "VICTOZA": 22.177711570348077}
\ No newline at end of file
+{"IBUPROFEN": 28.950730584148705, "NEULASTA": 587.2190421473565, "null": 1.2281475605569618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3542.json
index 962a0f7c81f..632d0279c69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3542.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3542.json
@@ -1 +1 @@
-{"FORXIGA": 19.655874266202463, "HUMALOG": 6.058077322015009, "INSULIN": 17.15085704601116, "JANUVIA": 15.163698231122646, "JARDIANCE": 30.20169478597335, "LANTUS": 9.0988217705689, "LEVEMIR": 16.062942918259004, "TRULICITY": 20.174378131012823, "VICTOZA": 18.19844092307215}
\ No newline at end of file
+{"OPSUMIT": 92.0281524073512, "TRACLEER": 36.71919103493391, "null": 2.6357887125861112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3543.json
index 9cdac010463..ee06844f351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3543.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3543.json
@@ -1 +1 @@
-{"ABASAGLAR": 46.47747577782364, "ACTOS": 10.490180977232145, "ACTRAPID": 10.672403628470969, "AFINITOR": 1.372307139646047, "APIDRA": 18.337459709271396, "ARANESP": 1.196336860601993, "BIKTARVY": 4.106038528650144, "BYDUREON": 21.4740385296052, "BYETTA": 11.171252323411396, "CANAGLIFLOZIN": 16.69390288220819, "DAPAGLIFLOZIN": 6.146722992521417, "DULAGLUTIDE": 44.57301064512043, "EMPAGLIFLOZIN": 7.112116025254086, "ENTRESTO": 1.2581643810214655, "EUCREAS": 20.25568493182673, "EXFORGE": 3.5103486248965994, "FIASP": 7.972596007124737, "FORXIGA": 13.664059049579135, "GALVUS": 13.7917851740662, "GLIBENCLAMIDE": 10.995062700252134, "HUMALOG": 30.898597816481185, "ICANDRA": 35.549503557834065, "INSULATARD": 5.99950847690032, "INSULIN": 26.81431476333669, "INVOKANA": 5.355835441293127, "ISOPHANE": 31.151325040449557, "JANUMET": 5.542291628235651, "JANUVIA": 6.906844466064206, "JARDIANCE": 12.317116876336312, "LANTUS": 22.41465178153746, "LATUDA": 1.6589103592600376, "LEVEMIR": 18.864414336949903, "LIPROLOG": 22.876231371127083, "LIRAGLUTIDE": 13.028983194478789, "LYUMJEV": 23.480798525429787, "METFORMIN": 29.01814730792279, "MIXTARD": 6.568116180033895, "NOVONORM": 14.670057517393955, "NOVORAPID": 8.753577792273283, "ONGLYZA": 8.674524125061561, "OPTISULIN": 126.52260579786405, "OZEMPIC": 8.699675955955563, "PASIREOTIDE": 17.48409997184417, "RASILEZ": 4.017675890279441, "REPAGLINIDE": 10.050717719234516, "RIVAROXABAN": 5.690617275314498, "RYBELSUS": 24.10586970371603, "SIGNIFOR": 27.43364251437124, "SOMATROPIN": 3.522666981774041, "TASIGNA": 1.3489648565911687, "TOUJEO": 29.2511753821142, "TRESIBA": 8.825457644016875, "TRULICITY": 28.468341355961996, "VICTOZA": 11.673120008489402, "VILDAGLIPTIN": 9.115781457933426}
\ No newline at end of file
+{"null": 2.376183710662081}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3544.json
index cac799371b4..5edc0f68d11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3544.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3544.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 5.513325469285062, "ARAVA": 1.544777014769863, "ATAZANAVIR": 7.948387479438012, "BYETTA": 31.809221402745628, "ENBREL": 2.9666740776207483, "FORSTEO": 1.2391923420203736, "GARDASIL": 1.028439408444723, "IRBESARTAN": 10.528454952190708, "JANUMET": 3.2624858475316123, "JANUVIA": 2.034800700527514, "LEMTRADA": 8.874795237480754, "NUCALA": 3.524571283344288, "PEGASYS": 1.888216344274242, "PEGINTRON": 3.4144234193954053, "SOMAVERT": 97.82226335142823, "TASIGNA": 2.552399816687647, "VICTOZA": 8.501316929733099, "ZOSTAVAX": 4.380409437500573, "null": 1.2916351381140223}
\ No newline at end of file
+{"ADEMPAS": 16.9709243175089, "APIDRA": 10.87085709235994, "FIASP": 56.746735137242574, "INSULIN": 3.171672103478413, "LANTUS": 8.739905254051013, "LEVEMIR": 38.121169651842486, "NOVORAPID": 81.82829397220559, "OMNITROPE": 96.78804880737115, "OPSUMIT": 13.2700709356036, "TRACLEER": 8.127515255569795, "TRESIBA": 19.87153211055292, "null": 2.0381617008548574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3545.json
index c195eb4e44c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3545.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3545.json
@@ -1 +1 @@
-{"BIKTARVY": 111.74457758253568}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3546.json
index 5eb1ba64582..6106b40dc6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3546.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3546.json
@@ -1 +1 @@
-{"LEMTRADA": 162.17114345446225}
\ No newline at end of file
+{"null": 3.7846578968294087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3547.json
index 5c54e9d53df..86cbc207b3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3547.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3547.json
@@ -1 +1 @@
-{"ADENURIC": 45.30652748015892, "ALENDRONATE": 93.34742101821249, "APIXABAN": 7.353852795158407, "ARANESP": 1.574201886978175, "ATRIPLA": 1.1424973530654017, "BOSULIF": 2.087145251971984, "BRILIQUE": 11.211158014684928, "BUMETANIDE": 5.032878512166839, "BYDUREON": 1.9394267084258017, "BYETTA": 3.015934234049155, "CELLCEPT": 1.16452200085653, "CICLOSPORIN": 1.286529789984708, "COAPROVEL": 2.684067517831332, "ELIQUIS": 2.4274453535780136, "ENTRESTO": 4.925266766803385, "EXFORGE": 3.8660730656265248, "FASLODEX": 1.0774283281572832, "FEBUXOSTAT": 90.03909919508094, "FORSTEO": 1.2454125339062605, "FORXIGA": 1.0503957036904252, "HUMALOG": 1.5435382164129834, "IBUPROFEN": 1.1527842002289257, "INLYTA": 1.512344886489528, "IRBESARTAN": 2.188177064547534, "JAKAVI": 1.86685447109566, "JANUMET": 3.858619869995816, "JANUVIA": 3.208445921147673, "JARDIANCE": 1.6274203953694124, "LEVEMIR": 1.177179713067151, "MEPOLIZUMAB": 1.2353147514903284, "MICARDIS": 2.1256618449660927, "OPSUMIT": 1.9146897418905997, "PLAVIX": 1.084575387274193, "REVATIO": 7.449146845248789, "STELARA": 1.3679945364489472, "SUTENT": 2.2147545035919376, "TASIGNA": 1.2711109743787778, "TICAGRELOR": 5.717688853474336, "TRACLEER": 1.2213705694060315, "TREMFYA": 2.410819836612428, "VELTASSA": 3.912958067469365, "XELJANZ": 1.5008482105536445, "XTANDI": 1.6032488431495076, "ZOSTAVAX": 6.056440480471248, "null": 1.181967925679437}
\ No newline at end of file
+{"AIMOVIG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3548.json
index f2be8e49ee6..d7d27461e64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3548.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3548.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 5.895164156482704, "null": 1.37971691359796}
\ No newline at end of file
+{"null": 3.988527135389572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3549.json
index 8cc319739bf..2f4e9d4afd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3549.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3549.json
@@ -1 +1 @@
-{"CICLOSPORIN": 24.132042619502297}
\ No newline at end of file
+{"null": 2.815800986427936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/355.json
index 312d1ceeb44..b2b6d16c7b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/355.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/355.json
@@ -1 +1 @@
-{"HUMALOG": 10.009123883071144, "HUMIRA": 8.850896569739021, "INVOKANA": 212.1455539523325, "JARDIANCE": 18.30594198260108, "LANTUS": 9.558251057920785, "OPTIMARK": 16.186119085325508}
\ No newline at end of file
+{"ABATACEPT": 1.6226737670441491, "ABILIFY": 1.9044674105959056, "ADALIMUMAB": 4.2306841929488135, "AERIUS": 1.4705536480402988, "AIMOVIG": 0.1890531083612224, "ALIMTA": 1.930655371851533, "AMINOSALICYLIC": 4.685938319955347, "ANAKINRA": 0.8852347318601792, "APIDRA": 1.423895200643737, "APIXABAN": 8.225927926599862, "APREMILAST": 1.4205358182856826, "APROVEL": 1.091665851464656, "ARANESP": 0.6732804557195203, "ARAVA": 3.333293201427815, "ARIPIPRAZOLE": 0.4371415797710823, "ATRIPLA": 0.0595706528584789, "AUBAGIO": 0.4800890789011016, "AVAMYS": 0.3553723408782318, "AVANDAMET": 1.709655002220209, "AVANDIA": 1.4899238536260992, "AXITINIB": 2.340739994288312, "AZATHIOPRINE": 0.4111347041871779, "BARACLUDE": 3.444889351983542, "BEDAQUILINE": 1.976851720198953, "BELANTAMAB": 29.4899366289344, "BENLYSTA": 1.8149227133660188, "BETAFERON": 2.0845571676533283, "BIKTARVY": 2.7364351129835174, "BOCEPREVIR": 3.8930880723798102, "BRAFTOVI": 1.1427009227527432, "BRIDION": 4.028966180498797, "BRINTELLIX": 0.9160510058010668, "BRIVIACT": 4.620994882885323, "BUDESONIDE": 0.1336120653013666, "BUPIVACAINE": 0.8247922341628603, "BUPRENORPHINE": 0.5733129460011974, "BYDUREON": 1.158579866960151, "BYETTA": 1.24172857177812, "CABOMETYX": 0.9230561822610244, "CANCIDAS": 2.683168765401404, "CERTOLIZUMAB": 9.47630056657221, "CERVARIX": 7.263108871264496, "CHLORHEXIDINE": 1.7040257226565472, "CIMZIA": 2.4037914747227824, "CLOPIDOGREL": 0.3863246245811257, "COMBIVIR": 0.4825576920186039, "COMIRNATY": 0.0090442115439017, "COSENTYX": 0.2061934388760543, "CUBICIN": 1.6011848040725567, "CYMBALTA": 0.6966964869303873, "CYTARABINE": 0.3172179686033803, "DARZALEX": 2.896361976859951, "DESCOVY": 2.226888134868513, "DEXAMETHASONE": 0.6422591465478856, "DOCETAXEL": 0.3836680607099711, "ELIQUIS": 5.680073406066571, "ELLAONE": 1.3060152131966478, "EMEND": 6.811978961626962, "EMTRICITABINE": 3.150107791354043, "ENALAPRIL": 8.35749858790516, "ENBREL": 1.274777581647473, "ENTYVIO": 1.6615787846075658, "ERLEADA": 1.5639902942535682, "EVENITY": 1.569634080469532, "EYLEA": 0.7430810215152012, "FASENRA": 0.4446252366090699, "FASLODEX": 0.8132505306089997, "FENTANYL": 0.8894579538343028, "FLORAJEN": 164.5255632399122, "FORSTEO": 0.3310618096789778, "GALAFOLD": 4.02219839339429, "GARDASIL": 3.220604709138017, "HUMALOG": 0.3478813930208064, "HUMIRA": 0.5690373682866547, "I": 96.01779975622595, "IBUPROFEN": 0.4376777649845827, "INCIVO": 0.518670211684239, "INFLIXIMAB": 2.9043522442495178, "INLYTA": 0.5343086512729911, "IPILIMUMAB": 1.031648108267743, "IRON": 5.082056096883587, "ISENTRESS": 13.660110318820315, "JANUMET": 7.309888809578701, "JANUVIA": 9.481294967558572, "KEPPRA": 1.1539557792297523, "KEYTRUDA": 12.32662067913909, "KYPROLIS": 1.0332639563466737, "LACOSAMIDE": 1.2045497467950013, "LANTUS": 1.722977416682229, "LEVETIRACETAM": 0.9965787262551284, "LOPINAVIR": 2.034811110146828, "LYNPARZA": 0.97625282731079, "LYRICA": 0.9498421552356764, "MULTAQ": 1.0195273672642315, "NEULASTA": 2.3149816439248965, "NEXAVAR": 0.5438226083016435, "NINLARO": 3.0525515701274557, "NORVIR": 2.237508494936895, "NOT": 3.590686376299836, "NOXAFIL": 22.59553898658379, "NPLATE": 0.5539056653057635, "NUCALA": 0.3653335752178221, "OLANZAPINE": 0.474602379226439, "ONGLYZA": 1.812096015974948, "OPDIVO": 0.6862584046178376, "OPSUMIT": 2.327185556149768, "PANTOPRAZOLE": 0.8073963242113632, "PEGASYS": 0.7373919344188404, "PEGINTERFERON": 2.486045021160743, "PEGINTRON": 2.0007126100283528, "PEMBROLIZUMAB": 3.386883259911374, "PLAVIX": 0.5508685875578642, "PREGABALIN": 0.7841808873024547, "QUTENZA": 2.314865840083234, "REBETOL": 2.837206819599785, "REMICADE": 2.713879902384888, "REYATAZ": 4.36861513039756, "RIBAVIRIN": 0.4074508066417591, "RINVOQ": 0.5906193897159648, "ROTATEQ": 1.7929161598790275, "RUBRACA": 27.40599369339656, "SHINGRIX": 0.2835569369376759, "SIMPONI": 2.8176810210453724, "SOLIRIS": 0.9147283422553866, "SPIKEVAX": 0.0348824501607831, "SPRYCEL": 11.49143040148586, "STELARA": 1.5330483734194698, "STIVARGA": 0.2504524775916019, "SUBOXONE": 3.933580020803972, "SYCREST": 6.207632202515212, "SYNAGIS": 1.225159937997084, "TEMODAL": 5.159673582685695, "TEMOZOLOMIDE": 1.802894331091012, "TOZINAMERAN": 0.0165405677339245, "TRACLEER": 0.6378689068513406, "TRELEGY": 0.7187656653337162, "TREMFYA": 0.699951101211558, "VAXZEVRIA": 0.0355460433313249, "VELTASSA": 2.1524767072561164, "VENETOCLAX": 1.8057164838635764, "VIMPAT": 1.1894066398089929, "VORICONAZOLE": 0.6630024219530283, "VOTRIENT": 2.106565205965936, "XARELTO": 1.8384486500674229, "XOFIGO": 1.42867428417818, "XTANDI": 1.9861329570102608, "YERVOY": 5.021723104558758, "ZEPATIER": 21.46923532415132, "ZOSTAVAX": 2.309491560303547, "ZYPREXA": 0.3559537029565387, "null": 1.1843867536101615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3550.json
index eff598dd253..26b792e3afe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3550.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3550.json
@@ -1 +1 @@
-{"MACI": 69022.96824143936}
\ No newline at end of file
+{"NOVORAPID": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3551.json
index bae06bff54f..3adc66bf6a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3551.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3551.json
@@ -1 +1 @@
-{"null": 1.2834577295116518}
\ No newline at end of file
+{"AIMOVIG": 8.769783502184014, "APIDRA": 10.49968894499498, "BYDUREON": 17.532699024301216, "COSENTYX": 15.192524602038237, "FASENRA": 18.499443453384167, "FIASP": 27.11253687493741, "INSULIN": 5.843258098079498, "LANTUS": 9.420284638780222, "LEVEMIR": 8.904560404107738, "NOVORAPID": 34.46600647967335, "SAXENDA": 9.49710710207634, "SEMGLEE": 367.6225842969492, "SIMPONI": 15.68306414615475, "STELARA": 4.521861170488066, "TOUJEO": 35.492507007626386, "TREMFYA": 14.98339610367361, "null": 1.489002717341325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3552.json
index cfa2f34f924..189249f609b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3552.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3552.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 67.08965016411776, "CICLOSPORIN": 61.00097059465603, "NEXOBRID": 3295.829608504337, "SOLIRIS": 50.3872008445028}
\ No newline at end of file
+{"AIMOVIG": 4.530449728304679, "APIDRA": 10.147263071705355, "BYDUREON": 21.70642999205092, "BYETTA": 4.649818286858428, "COSENTYX": 2.134034512491962, "FASENRA": 21.57793151431052, "FIASP": 28.734911725280774, "LANTUS": 7.268399878196354, "LEVEMIR": 11.085348981661967, "NOVORAPID": 42.28891372938724, "OPSUMIT": 4.328454760771451, "SAXENDA": 10.632177693672356, "SIMPONI": 2.190513351021554, "TOUJEO": 18.7685460851876, "TRESIBA": 33.95545828507519, "null": 3.2382124078806505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3553.json
index baf2340b8af..27137462bd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3553.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3553.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 40.33917729872454, "ASPARAGINASE": 8.361455674225297, "AZACITIDINE": 7.677888281745559, "AZATHIOPRINE": 6.007800761251951, "BASILIXIMAB": 19.152850863362566, "BLINATUMOMAB": 18.058109803042903, "BORTEZOMIB": 6.88856001544937, "BUDESONIDE": 2.4085773892941043, "BUSILVEX": 23.23780984134875, "BUSULFAN": 138.00101125312173, "CANCIDAS": 7.090237349909074, "CARMUSTINE": 19.98814560118569, "CASPOFUNGIN": 7.052988596759614, "CELLCEPT": 7.418064076304272, "CICLOSPORIN": 74.75093640227017, "CYTARABINE": 5.862931451392072, "DEFITELIO": 72.64573373980406, "DEXAMETHASONE": 1.1139127809981544, "EMEND": 10.95782757742808, "EXJADE": 5.228228663555145, "FILGRASTIM": 14.274505669524556, "GANCICLOVIR": 25.46792910769731, "ICLUSIG": 14.359605768883863, "JAKAVI": 8.90029176339465, "KYMRIAH": 3.204861424632776, "METHOTREXATE": 4.565569365925122, "MYCOPHENOLATE": 15.416641353226195, "NOXAFIL": 30.741090940429768, "POSACONAZOLE": 16.864822357495758, "RAPAMUNE": 14.836480259728772, "RITUXIMAB": 1.2477302090576727, "RUXOLITINIB": 7.164081477653011, "SOLIRIS": 9.755736146155233, "SPRYCEL": 4.342558962680672, "TACROLIMUS": 26.73033623851588, "TEPADINA": 383.9366784620941, "TOBRAMYCIN": 10.042811175242203, "VFEND": 5.906064883103782}
\ No newline at end of file
+{"null": 0.5899625428937079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3554.json
index 4b29b839047..2f965983e9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3554.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3554.json
@@ -1 +1 @@
-{"CICLOSPORIN": 56.84382199786557}
\ No newline at end of file
+{"SIMPONI": 225.04004545805984, "STELARA": 33.05235706914827, "TREMFYA": 86.10043408502275, "null": 0.5225902213409184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3555.json
index 4c00fcf5b69..030666f2ec4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3555.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3555.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 32.958702216088405, "AZATHIOPRINE": 7.32398369749477, "BASILIXIMAB": 82.80753994802072, "BORTEZOMIB": 12.998549725714092, "BUDESONIDE": 12.768010759117397, "BUSULFAN": 86.22048577833976, "CANCIDAS": 37.73632313185117, "CELLCEPT": 4.485700010727057, "CICLOSPORIN": 94.0958374696237, "CIDOFOVIR": 145.9283893197127, "CYTARABINE": 14.277123102281712, "GANCICLOVIR": 19.20732665701491, "ICLUSIG": 12.296544679845432, "JAKAVI": 4.947700989967922, "METHOTREXATE": 4.449219040248449, "MYCOPHENOLATE": 33.62392949366133, "NOXAFIL": 20.70373000431945, "SOLIRIS": 3.332435899124008, "TACROLIMUS": 27.46189931928016, "THIOTEPA": 177.81909816834084}
\ No newline at end of file
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3556.json
index 2af1f9a05e5..c71c8ce4f5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3556.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3556.json
@@ -1 +1 @@
-{"BUDESONIDE": 10.783336630377672, "BUSULFAN": 44.62080980683538, "CICLOSPORIN": 92.05462740404153}
\ No newline at end of file
+{"AIMOVIG": 207.11479710356355, "ARANESP": 32.493352108021995, "BYDUREON": 6.16806434344142, "COSENTYX": 4.432970567587728, "EYLEA": 6.087421919435592, "LANTUS": 1.1906864093032268, "ROACTEMRA": 4.17605679818807, "null": 1.1832493169138742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3557.json
index c9cd2a3aaf7..3b5e3673f94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3557.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3557.json
@@ -1 +1 @@
-{"BUSULFAN": 106.16440527464154, "CELLCEPT": 16.736195093747018, "CICLOSPORIN": 48.49454091149225}
\ No newline at end of file
+{"ADCIRCA": 23.1153981589487, "BUPIVACAINE": 14.969554327711522, "ELIQUIS": 1.110588221843161, "FENTANYL": 1.8894868128245768, "FORSTEO": 12.878530470532452, "HYDROCORTISONE": 36.76049770910342, "IBUPROFEN": 14.110663322031057, "ILARIS": 365.3609996775903, "NEULASTA": 145.9650241685922, "OPSUMIT": 38.54839277310927, "RITUXIMAB": 3.752966680516759, "SPINRAZA": 22.001517168446597, "TESTOSTERONE": 34.05992900066411, "TRACLEER": 7.139094717105061, "null": 1.2759054133220475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3558.json
index 237a071eb18..8de5791a6d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3558.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3558.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 77.87851517315042, "AZACITIDINE": 13.551880321876038, "AZATHIOPRINE": 7.593960279878285, "BASILIXIMAB": 61.14477896990847, "BUDESONIDE": 10.127750003212604, "BUSULFAN": 139.3816112027737, "CELLCEPT": 3.4418839790780487, "CICLOSPORIN": 89.035771174271, "CYTARABINE": 9.656865195379297, "ICLUSIG": 27.43963679183444, "JAKAVI": 6.3151857302981576, "MELPHALAN": 37.25819953393263, "METHOTREXATE": 4.513754711445736, "MYCOPHENOLATE": 35.86845437186013, "THIOTEPA": 66.86096760754364}
\ No newline at end of file
+{"null": 2.413403845081248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3559.json
index 8327da09f33..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3559.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3559.json
@@ -1 +1 @@
-{"OLANZAPINE": 19.55065459329453, "PANTOPRAZOLE": 56.5453531010181, "null": 2.1468283283529}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/356.json
index 41832402c94..5eb6ebf2bb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/356.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/356.json
@@ -1 +1 @@
-{"ABACAVIR": 1.5886654167540808, "ASPARAGINASE": 15.8399167838061, "BEDAQUILINE": 3.8008549373551954, "BOSULIF": 3.89819793428598, "BRAFTOVI": 4.011982399454651, "BYDUREON": 3.8195740959409608, "BYETTA": 5.246513096176721, "CABOMETYX": 3.057318185318336, "CELLCEPT": 3.8808583885688095, "CICLOSPORIN": 1.0588941337281963, "COMBIVIR": 3.834942172549373, "CRIXIVAN": 19.871550489325063, "CYTARABINE": 1.796547134033389, "DEXAMETHASONE": 1.4340815046620594, "EFAVIRENZ": 3.2901406815407586, "EPIVIR": 7.52748075588499, "EUCREAS": 29.46604981944361, "EXJADE": 1.6611652844363658, "FENTANYL": 1.604966244438802, "FORXIGA": 1.5483755687350524, "GALVUS": 22.13792651303727, "GLIVEC": 6.833184366588426, "ICLUSIG": 12.601941774524814, "INLYTA": 1.8448965996703028, "IPILIMUMAB": 2.085031515863356, "ISENTRESS": 5.3371456338815255, "JANUMET": 8.181117647102, "JANUVIA": 9.30897824846138, "JARDIANCE": 2.233571832938553, "KALETRA": 3.4756196684254057, "KEPPRA": 1.7737688114402217, "KEYTRUDA": 4.406406651186828, "MEKINIST": 2.317058432512847, "MERCAPTOPURINE": 7.198305564678553, "NEXAVAR": 11.204096282799698, "NILOTINIB": 9.21739275793892, "OLANZAPINE": 1.2860070575222726, "ONCASPAR": 12.987830257816848, "OPDIVO": 4.95806308725641, "PAZOPANIB": 5.899918398429357, "PEMBROLIZUMAB": 1.5249589411526598, "RYBELSUS": 5.673064002975826, "SAXENDA": 7.238104714883996, "STIVARGA": 1.4538691946563744, "SUTENT": 1.0296757233580924, "TAGRISSO": 1.8206191673848968, "TASIGNA": 17.283809620785814, "TRULICITY": 11.333830904616011, "VICTOZA": 16.046099336631087, "VIREAD": 4.285906087678335, "VOTRIENT": 3.026984729139077, "ZIAGEN": 18.37404941793895, "ZYPREXA": 2.560621699453914, "null": 1.350924268983533}
\ No newline at end of file
+{"COMIRNATY": 1.6251356926099032, "GARDASIL": 25.915461537995174, "SPIKEVAX": 1.6262237443254393, "VAXZEVRIA": 4.794937383502068, "null": 0.1277431063113188}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3560.json
index 9919362f68a..c6490dabd28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3560.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3560.json
@@ -1 +1 @@
-{"AVASTIN": 12.49142713088438, "AZACITIDINE": 38.3197928802718, "BEVACIZUMAB": 7.388076152621527, "CAPECITABINE": 7.505568839924707, "CYTARABINE": 8.331078621858817, "DARZALEX": 11.924019192374526, "DOCETAXEL": 29.809336165949333, "DOXORUBICIN": 34.600772447016915, "ERBITUX": 83.49082057305466, "HERCEPTIN": 8.519913535980328, "IBRANCE": 2.099639522465786, "INTRONA": 33.74502690751007, "MABTHERA": 37.55484819352679, "METHOTREXATE": 1.8790682365033515, "OLANZAPINE": 1.1566157578795009, "PACLITAXEL": 8.950975550845312, "PEGASYS": 7.660713173576283, "RITUXIMAB": 21.691994480770685, "TEGAFUR": 35.40515316876338, "XELODA": 20.84968282235198, "ZYPREXA": 1.1053757376666982, "null": 1.981583948942982}
\ No newline at end of file
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3561.json
index d31229f3ff6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3561.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3561.json
@@ -1 +1 @@
-{"ALIMTA": 2.359095986139691, "AVASTIN": 1.7996414137348795, "BEVACIZUMAB": 1.956579136704886, "BUSULFAN": 4.39736253958738, "CAPECITABINE": 5.69076160390638, "CARMUSTINE": 6.7464046521267225, "CELLCEPT": 3.452063718030019, "COMBIVIR": 5.003781314045828, "CYTARABINE": 7.421318138289921, "DEXAMETHASONE": 1.9486983343423592, "DOCETAXEL": 16.80505747082617, "DOXORUBICIN": 22.54769059679511, "ERBITUX": 14.45696738715262, "FULVESTRANT": 5.26642854822267, "GANCICLOVIR": 8.082643050731505, "HALAVEN": 4.471960678263996, "HERCEPTIN": 4.195554295358837, "INTRONA": 6.9871829463236335, "KEPPRA": 1.6010910069999131, "KISQALI": 3.364686094082049, "LEVOFLOXACIN": 2.5016452355849217, "MABTHERA": 12.533068739759791, "METHOTREXATE": 2.2536571219641703, "OLANZAPINE": 4.1550398468896415, "PACLITAXEL": 10.158033815969738, "PEGASPARGASE": 22.93374745433444, "PEGASYS": 5.520841947653116, "PEGINTRON": 2.4157308133168165, "PEMBROLIZUMAB": 1.7474524216331488, "PLAVIX": 4.277655841332218, "RIBAVIRIN": 2.226818705440337, "RIBOCICLIB": 6.4494456038953, "RITUXIMAB": 6.603366785039535, "ROACTEMRA": 1.181585776966416, "TAMIFLU": 1.6700639119696346, "TAXOTERE": 10.188942004006318, "XELODA": 9.202547515220974, "ZYPREXA": 2.1178301208937627, "null": 3.2201607327241057}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3562.json
index ce2ab8b193e..c59f92f7853 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3562.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3562.json
@@ -1 +1 @@
-{"null": 1.714446196703803}
\ No newline at end of file
+{"COMIRNATY": 0.6614426493310113, "null": 2.155375136308089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3563.json
index 394f94dd1c3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3563.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3563.json
@@ -1 +1 @@
-{"ABACAVIR": 1.961251477282365, "ABATACEPT": 2.030698364835504, "ACLIDINIUM": 23.244855531122948, "ADALIMUMAB": 3.106849179819504, "ALEMTUZUMAB": 10.468145625487544, "CELECOXIB": 9.121386530223866, "CICLOSPORIN": 3.484937698625681, "EFAVIRENZ": 37.47050818838971, "ENTYVIO": 3.609249612532609, "GARDASIL": 2.058729047525755, "IPILIMUMAB": 6.016820916352349, "JANUMET": 2.6033921909001174, "KEYTRUDA": 1.1703459611016869, "LAMIVUDINE": 10.70561463647167, "MEPOLIZUMAB": 10.26227057793576, "PEGINTERFERON": 5.031263637677742, "XOLAIR": 1.8051274695040065, "null": 1.0629066549450938}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3564.json
index 3849d88b6c4..d9e4d1a0ecb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3564.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3564.json
@@ -1 +1 @@
-{"ARAVA": 1.1125877727907745, "COMIRNATY": 1.0618943018712632, "LANTUS": 3.1316632171121155, "ROACTEMRA": 10.954148654951895, "TOZINAMERAN": 1.3234910567177725}
\ No newline at end of file
+{"ACTRAPID": 44.81649003706615, "APIDRA": 2.672476856114626, "BUPIVACAINE": 9.69048872052797, "BYDUREON": 2.457607749791424, "COSENTYX": 0.9921263094602508, "FENTANYL": 2.000824602630439, "FIASP": 51.76459076685835, "FORSTEO": 2.7651860017942638, "HUMALOG": 0.7853826269504487, "LANTUS": 0.8665377741837617, "LEVEMIR": 57.05664696677923, "MIXTARD": 29.74375471385549, "NEULASTA": 10.341102686313691, "NOVORAPID": 82.02429363915127, "OPSUMIT": 1.172609050143935, "SAXENDA": 4.389112637582569, "SIMPONI": 4.061746368499207, "TRESIBA": 20.800436049713444, "VICTOZA": 4.662707564629159, "null": 3.9641428693083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3565.json
index 13a24757f65..7c84c501d77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3565.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3565.json
@@ -1 +1 @@
-{"ABATACEPT": 15.88039528634048, "ADALIMUMAB": 26.57864400273933, "APREMILAST": 113.51445573635232, "ARAVA": 9.644300144015356, "AZATHIOPRINE": 7.127619649037255, "CICLOSPORIN": 7.948138457852394, "ENBREL": 73.18989470067538}
\ No newline at end of file
+{"LEFLUNOMIDE": 1471.0029315398006}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3566.json
index 08725300ab8..aae86cc663f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3566.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3566.json
@@ -1 +1 @@
-{"CICLOSPORIN": 3.9626572701266256, "COMIRNATY": 1.0666643762039176}
\ No newline at end of file
+{"ENTRESTO": 245.0806903727404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3567.json
index 08e65114c18..496bf51e781 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3567.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3567.json
@@ -1 +1 @@
-{"ARAVA": 4.924562288271879}
\ No newline at end of file
+{"LANTUS": 4.119975245705015, "null": 8.098926870042071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3568.json
index f9ceda59d6f..47c7bf06b18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3568.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3568.json
@@ -1 +1 @@
-{"FUZEON": 906.3244014727634, "PEGASYS": 4.532703579706318, "null": 1.144234496993038}
\ No newline at end of file
+{"HUMALOG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3569.json
index b0537d2dbc0..36e268b6377 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3569.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3569.json
@@ -1 +1 @@
-{"null": 1.561918659840594}
\ No newline at end of file
+{"FIASP": 326.8879385087757, "LEVEMIR": 61.77425229953794, "NOVORAPID": 239.31987965208108, "TRESIBA": 99.2502740045125, "null": 1.4225108579924677}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/357.json
index 12aba73ab6e..cc6ced4840f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/357.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/357.json
@@ -1 +1 @@
-{"BORTEZOMIB": 25.58679349938668, "DEXAMETHASONE": 7.698644359007879, "ELIQUIS": 3.873646565574226, "ENTRESTO": 7.154680796279707, "INSULIN": 15.648880866836375, "LANTUS": 4.119105636990184}
\ No newline at end of file
+{"null": 0.8677991842204672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3570.json
index 42bc261ca2b..951dcef93fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3570.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3570.json
@@ -1 +1 @@
-{"ACLIDINIUM": 12.300312738030945, "AIMOVIG": 1.2329314495646464, "ALEMTUZUMAB": 48.07766711559017, "ATAZANAVIR": 7.177943039175762, "AUBAGIO": 1.632576407510744, "COMBIVIR": 3.986201971449111, "COMIRNATY": 1.5466109035827824, "COSENTYX": 1.138377776422446, "EFAVIRENZ": 13.71603784859098, "GARDASIL": 1.087912864855625, "HUMALOG": 1.1381294668790185, "KEYTRUDA": 2.151061098207687, "LEMTRADA": 126.5616172045172, "OPDIVO": 3.2690845328398903, "OPSUMIT": 1.0447998376745344, "PEGASYS": 4.517214762417995, "PEGINTERFERON": 7.60540509998259, "PEGINTRON": 12.593643762371324, "RIBAVIRIN": 7.182308576945927, "STELARA": 2.1790196192723497, "TOZINAMERAN": 1.5767960603277975}
\ No newline at end of file
+{"BUPIVACAINE": 34.578527018404465, "HYQVIA": 134.69183638673329, "OPSUMIT": 18.76911397851554, "SIMPONI": 6.01650973874846, "TRACLEER": 14.312000949565482, "null": 3.055474937208127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3571.json
index 133c7ad3b67..429325263c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3571.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3571.json
@@ -1 +1 @@
-{"ARAVA": 1.5631669963963233, "PEGASYS": 2.6643805846401776, "null": 1.2270427596831233}
\ No newline at end of file
+{"EPOETIN": 9632.533523763224, "null": 0.7960280398871976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3572.json
index a76a7eec579..c7722da420e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3572.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3572.json
@@ -1 +1 @@
-{"null": 2.5907254632306738}
\ No newline at end of file
+{"null": 1.9046738537938133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3573.json
index dcc54db5808..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3573.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3573.json
@@ -1 +1 @@
-{"ZOSTAVAX": 14.152414596794053, "null": 2.2259207123210967}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3574.json
index c8717ed2c9a..5c8ecb2949b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3574.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3574.json
@@ -1 +1 @@
-{"MIDAZOLAM": 42.87806276964111, "null": 1.8004263423785136}
\ No newline at end of file
+{"ACTRAPID": 9.381893517130438, "AIMOVIG": 15.218411781893533, "APIDRA": 25.29428294174176, "ARANESP": 1.984229018950804, "BUDESONIDE": 0.8338186694734183, "BYDUREON": 21.43481669260929, "BYETTA": 3.7718318427895663, "CICLOSPORIN": 0.4247931071057296, "CIMZIA": 6.347843877272049, "COSENTYX": 9.567584782151169, "ENTYVIO": 1.8292879250004397, "EVENITY": 2.773834576914907, "FASENRA": 4.163582191927951, "FIASP": 27.175116472167836, "HUMIRA": 1.3111992693121628, "IBUPROFEN": 0.6551481869390818, "INBRIJA": 63.90759022640978, "INHIXA": 27.629176552394394, "INSULATARD": 13.539088830764417, "INSULIN": 6.81013712914356, "LANTUS": 22.43784681854332, "LEVEMIR": 17.537552892008122, "NEULASTA": 19.71660762164136, "NOVORAPID": 30.271447190621178, "OMNITROPE": 94.3523044656571, "OPSUMIT": 3.1915367517936857, "ROACTEMRA": 1.9355804778090009, "SAXENDA": 3.0876532440296365, "SEMGLEE": 208.83513639037133, "SIMPONI": 17.45568090724596, "SKYRIZI": 13.528436062341603, "STELARA": 3.995291904146191, "TOUJEO": 29.77402528459545, "TRACLEER": 1.7754994212511832, "TREMFYA": 55.76397629723306, "TRESIBA": 16.85370270097791, "VICTOZA": 3.4451539829503046, "null": 1.1568748884907838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3575.json
index 587c0fa685d..8bf367bb239 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3575.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3575.json
@@ -1 +1 @@
-{"ADALIMUMAB": 15.109989719144576, "AMINOSALICYLIC": 278.6191839434603, "COVID19": 2.412841223328144}
\ No newline at end of file
+{"null": 0.8927233659844568}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3576.json
index acf6f8b5b9e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3576.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3576.json
@@ -1 +1 @@
-{"ABATACEPT": 7.826887145723598, "ADALIMUMAB": 19.0846999528507, "ALEMTUZUMAB": 2.982527248391108, "ANAKINRA": 4.428822769221017, "APREMILAST": 93.42765945488998, "ARAVA": 3.094889078082489, "AUBAGIO": 3.806296054913129, "CIMZIA": 5.76231782224933, "COSENTYX": 3.018134458158565, "ENBREL": 3.462629443539892, "ENTYVIO": 1.8583598906538132, "GARDASIL": 1.5470951861899611, "HUMIRA": 4.385045785005532, "IBUPROFEN": 6.159766234808938, "LEFLUNOMIDE": 8.337991583931341, "LYRICA": 1.5609698683902613, "METHOTREXATE": 29.255564376239136, "OPTIMARK": 2.8069519582839337, "PANTOPRAZOLE": 4.580796621850888, "RITUXIMAB": 1.78908209902937, "TOZINAMERAN": 1.1488947351264318, "XELJANZ": 3.4731940380903303, "XOLAIR": 1.6567193449328668}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3577.json
index 9c67d823b5d..50624adafc8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3577.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3577.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.570070518462994, "CIMZIA": 5.151651163105396, "JARDIANCE": 12.226608019564498, "SIMPONI": 9.834170372315082}
\ No newline at end of file
+{"AIMOVIG": 5.256034030510369, "APIDRA": 6.972398542540467, "BYDUREON": 73.82447861768219, "BYETTA": 6.8978785488455605, "COSENTYX": 5.1105172906562055, "ENTYVIO": 3.0827337890570297, "FASENRA": 45.04834540700293, "FIASP": 14.105993215069086, "LANTUS": 3.886989024072257, "LEVEMIR": 9.966689769277258, "NEULASTA": 12.716821159065075, "NOVORAPID": 26.337881743047948, "OPSUMIT": 21.338061303036653, "PEGASYS": 0.858783094097034, "SIMPONI": 17.052844383176964, "STELARA": 3.061982861983466, "TOUJEO": 6.918160748120319, "TRACLEER": 12.499527746502226, "TREMFYA": 45.16241213759934, "VICTOZA": 3.250758922284854, "null": 1.3402132209774582}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3578.json
index 06c61cfaf05..fd238bb14e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3578.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3578.json
@@ -1 +1 @@
-{"CELLCEPT": 23.92621648169678, "JARDIANCE": 18.224603545051057}
\ No newline at end of file
+{"FORSTEO": 44.55729213838868, "null": 0.6184948816365008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3579.json
index 41399355ff7..bf555123f26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3579.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3579.json
@@ -1 +1 @@
-{"BONVIVA": 5.077553307451468, "CAPECITABINE": 2.198956081251413, "CICLOSPORIN": 1.7670148695013952, "COMIRNATY": 1.4848591278301808, "COSENTYX": 1.3612561455451533, "COVID19": 1.442553143683863, "EVENITY": 6.792578362636017, "EXFORGE": 1.833164754143561, "FASLODEX": 1.734170339836344, "FORSTEO": 3.8070888145895, "GARDASIL": 1.426344990493844, "HUMIRA": 3.379010458470165, "PEMBROLIZUMAB": 2.294625599913508, "RINVOQ": 1.665276814481762, "SHINGRIX": 2.608380318746482, "SPIKEVAX": 1.2413825098647555, "SUTENT": 1.2606340111734444, "TOZINAMERAN": 1.966991015906614, "VAXZEVRIA": 1.1502314822772135, "XELJANZ": 1.4509146477894646, "XTANDI": 1.8139524935889977, "ZOSTAVAX": 1.1181931133832428}
\ No newline at end of file
+{"IBUPROFEN": 743.4573162383549}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/358.json
index 5c33bee1335..4fceeb441f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/358.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/358.json
@@ -1 +1 @@
-{"COMIRNATY": 1.202703213778669, "COSENTYX": 2.492841703011177, "ENBREL": 3.6315243472946697, "GARDASIL": 2.941585496084374, "RILUTEK": 287.1360725659436, "SIMPONI": 2.794034625955135, "null": 1.0742616530282312}
\ No newline at end of file
+{"ABILIFY": 0.6170487205189019, "ACETYLSALICYLIC": 57.00408155795449, "ADALIMUMAB": 20.489805998400367, "AIMOVIG": 3.875114857249074, "APIDRA": 2.8796795346480057, "APREMILAST": 12.46491837827897, "ARAVA": 1.6724831221284298, "BENLYSTA": 0.9015311616442204, "BUDESONIDE": 0.9491859043051368, "CIMZIA": 0.4554434586341326, "COMBIVIR": 2.0468256303664703, "COMIRNATY": 1.0841839219492757, "CYMBALTA": 1.3876064225074272, "ENBREL": 1.9005441740561717, "GARDASIL": 1.2823919529159238, "HIZENTRA": 2.653995176128208, "HUMIRA": 0.9924638423209936, "INSULIN": 3.797090181500917, "IRON": 6.436463579806, "KEPPRA": 0.8231386194589251, "KEYTRUDA": 1.1788218850069163, "LANTUS": 5.155905148734833, "LEVOFLOXACIN": 0.6277494210929025, "NEXAVAR": 1.451790831923561, "PANTOPRAZOLE": 1.87912581841695, "PEGASYS": 0.7993703250332252, "PIRFENIDONE": 48.55819001664136, "RILUTEK": 52.27602465770154, "SHINGRIX": 2.343686588602761, "SPIKEVAX": 0.5238955299278172, "TOZINAMERAN": 0.1009889167632008, "VAXZEVRIA": 0.1596938133047397, "ZOSTAVAX": 0.586524469019494, "null": 0.7460635304889139}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3580.json
index 34ad46fa121..03698df4d89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3580.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3580.json
@@ -1 +1 @@
-{"null": 5.949776680630173}
\ No newline at end of file
+{"ABASAGLAR": 2.7363928615479134, "ACTRAPID": 13.21741262764763, "AIMOVIG": 4.726816190446971, "APIDRA": 5.667831814793046, "BUMETANIDE": 11.105642019747, "BYDUREON": 21.44232791186801, "BYETTA": 3.97291368325473, "CICLOSPORIN": 0.4982727677598312, "CIMZIA": 0.3459838525553778, "COSENTYX": 3.2657881724918263, "DUORESP": 29.30231259500156, "ELIQUIS": 0.1443731112022572, "ENTRESTO": 1.3778597719338712, "ENTYVIO": 0.6107364426020472, "ERENUMAB": 7.634974583620242, "FASENRA": 4.342542102775939, "FIASP": 16.337244159132315, "HUMALOG": 0.194872922586367, "HYDROCORTISONE": 6.385498762048218, "IBUPROFEN": 2.5455265988379234, "INSULATARD": 11.843774814367356, "INSULIN": 0.8503985958608632, "LANTUS": 31.86366459125246, "LEVEMIR": 30.102981042367105, "NEULASTA": 7.125461174583649, "NOVORAPID": 24.46329778380651, "OMNITROPE": 17.31809282196066, "OPSUMIT": 2.9254104266054086, "PLEGRIDY": 3.224126797843517, "ROACTEMRA": 0.646222513342287, "SAXENDA": 5.053351282439603, "SIMPONI": 11.005562053160387, "STELARA": 1.1530086758223028, "TERROSA": 17.42239485942071, "TESTOSTERONE": 6.032849269129476, "TRACLEER": 2.356471818319452, "TREMFYA": 24.720262477258647, "TRESIBA": 15.91675563628298, "VICTOZA": 4.114518891571745, "null": 2.264185226305398}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3581.json
index da3619e6278..579f3b969b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3581.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3581.json
@@ -1 +1 @@
-{"COVID19": 1.114497575047391, "FORSTEO": 28.14653158629961, "SPIKEVAX": 3.138813132716742}
\ No newline at end of file
+{"null": 2.04906311183661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3582.json
index 0c417fc9f9f..2479a4e31b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3582.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3582.json
@@ -1 +1 @@
-{"null": 2.216280710420783}
\ No newline at end of file
+{"LANTUS": 10.136513735531986, "LEVEMIR": 19.43735438959756, "NOVORAPID": 53.044979115324686, "SAXENDA": 31.536713402270976, "SEMGLEE": 3579.844043190258, "null": 1.68099751827224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3583.json
index 406286f3903..ac64aedef23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3583.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3583.json
@@ -1 +1 @@
-{"null": 1.7536218077500911}
\ No newline at end of file
+{"AMBRISENTAN": 17.347753591515986, "ANGIOX": 152.72878465706273, "BRILIQUE": 11.184911299990402, "BUMETANIDE": 41.90979623314222, "BYDUREON": 4.8026589553225865, "CLOPIDOGREL": 6.161473934458488, "COSENTYX": 1.6881737704529385, "EFIENT": 21.232012085761024, "ELIQUIS": 0.6724312115298445, "FIASP": 26.088542357191265, "JANUMET": 3.1580172323444624, "JANUVIA": 3.321174009284645, "LANTUS": 1.5589277628715006, "LEVEMIR": 7.442635674530234, "NEULASTA": 8.743292289169052, "NOVORAPID": 11.121859766794302, "OMNITROPE": 52.455892848644005, "OPSUMIT": 9.978928767721875, "PLAVIX": 12.188039163219878, "SIMPONI": 4.421954000028527, "STELARA": 0.8934190995632887, "TOUJEO": 10.82765539844747, "TRACLEER": 11.960816242960972, "TREMFYA": 11.79561858675616, "null": 1.7182648327154713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3584.json
index 38afe8a69e1..2130590af37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3584.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3584.json
@@ -1 +1 @@
-{"BUDESONIDE": 37.27284409884139, "null": 1.620210718263554}
\ No newline at end of file
+{"APIDRA": 149.25142948528253, "BETAFERON": 29.42985552102633, "INSULIN": 15.361646133155457, "LANTUS": 181.94847243749783, "TOUJEO": 243.5743004184508, "null": 0.0762116816860971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3585.json
index b49a49c387e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3585.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3585.json
@@ -1 +1 @@
-{"ASPARAGINASE": 42.254489806209534, "CYMBALTA": 9.343551457553852, "MICARDIS": 141.43696076294944}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3586.json
index 3bab20cf2be..694ac3b9c03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3586.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3586.json
@@ -1 +1 @@
-{"BUDESONIDE": 8.20655810009678, "CANAKINUMAB": 397.05889983740735, "CICLOSPORIN": 6.521487594312666, "CYMBALTA": 1.428233845268226, "FLUTICASONE": 69.49114487978238, "HYDROCORTISONE": 8.08080788756608, "KEPPRA": 3.8445530073409455, "METHOTREXATE": 6.372239753599802, "OMNITROPE": 106.84320022944836, "ROTATEQ": 5.562266355780661, "null": 3.9330467254331314}
\ No newline at end of file
+{"null": 8.51221194236734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3587.json
index f8a09a79690..e5b5bc2081b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3587.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3587.json
@@ -1 +1 @@
-{"GARDASIL": 5.4154000492976, "TOZINAMERAN": 1.292418035476442, "null": 1.4147448205029352}
\ No newline at end of file
+{"OPSUMIT": 10.188213071297127, "TRACLEER": 9.672664379727996, "null": 2.523171654739543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3588.json
index 560765f0e74..c6835180ec8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3588.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3588.json
@@ -1 +1 @@
-{"AMIKACIN": 1.8237268755068787, "BEXSERO": 3.5498812893631344, "BRAFTOVI": 1.151701961380143, "BUSULFAN": 2.506890657431361, "COMIRNATY": 1.5916699875606664, "COVID19": 2.2288497602240107, "EPIVIR": 2.279550551440222, "FLUCELVAX": 9.293551023532748, "GARDASIL": 8.890485041552422, "HUMAN": 2.1335010644205, "IPILIMUMAB": 7.194192879250318, "KEYTRUDA": 3.1850342270855, "LEVETIRACETAM": 1.11662109778435, "MABCAMPATH": 13.43619225958807, "MENVEO": 5.002027772462974, "NIMENRIX": 2.0029548703560405, "OPDIVO": 3.6578166407226256, "PEGINTERFERON": 1.2497691262129766, "PEGINTRON": 1.5265590610988369, "PEMBROLIZUMAB": 3.499112921541484, "PREVENAR": 4.573572164922204, "RAPAMUNE": 1.9060220405636668, "SHINGRIX": 13.135795378956232, "SPIKEVAX": 1.0496568167756712, "STELARA": 1.1900311176804814, "TOZINAMERAN": 2.418381236233508, "TWINRIX": 12.979841354061328, "VAXZEVRIA": 4.132908539748054, "VFEND": 1.970564485599464, "YERVOY": 4.97783944956507, "ZOSTAVAX": 2.992409264921013}
\ No newline at end of file
+{"null": 3.1560025990362823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3589.json
index eb16bafefe7..2ce5a7d9c4f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3589.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3589.json
@@ -1 +1 @@
-{"FENTANYL": 5.6548003834943055, "SUBOXONE": 37.69069877343805, "null": 3.0802216977826347}
\ No newline at end of file
+{"IBUPROFEN": 62.711849612710495, "null": 4.714301196822658}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/359.json
index ff1aa544819..e9eecb8bc4f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/359.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/359.json
@@ -1 +1 @@
-{"AVAMYS": 19.565235765802377}
\ No newline at end of file
+{"CICLOSPORIN": 24.13007338194789, "null": 0.5240809513364117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3590.json
index aa699156398..44e6dfa97b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3590.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3590.json
@@ -1 +1 @@
-{"CICLOSPORIN": 4.641848162781707, "CIMZIA": 3.6914724927390754, "COMIRNATY": 1.1068026500633843, "COSENTYX": 11.3743299482559, "COVID19": 1.2670571057407332, "STELARA": 36.026738477223056, "TREMFYA": 30.66734502213607}
\ No newline at end of file
+{"null": 8.407219522545795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3591.json
index 259addabaea..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3591.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3591.json
@@ -1 +1 @@
-{"ABILIFY": 5.557026528778535, "ARIPIPRAZOLE": 5.567180546832834, "BIKTARVY": 4.400034294832929, "BRILIQUE": 1.311610126427852, "BRINTELLIX": 1.6482045765478066, "CLOPIDOGREL": 2.200967300385809, "COMBIVIR": 3.2681477364346936, "EFAVIRENZ": 9.480367940897343, "ENTRESTO": 4.515124351117639, "ENZALUTAMIDE": 8.348679304373578, "EXFORGE": 3.0080356730993576, "INVEGA": 92.28047410441224, "ISENTRESS": 2.9017703011169007, "JANUVIA": 1.010316666896486, "KAFTRIO": 3.0776404721652773, "KALETRA": 1.1778126890890728, "MICARDIS": 2.5876431706376444, "NORVIR": 3.833056649095538, "OLANZAPINE": 2.882632510130985, "PRIVIGEN": 3.709308692450034, "RASILEZ": 3.058078914914629, "REYATAZ": 9.93630983269045, "RISPERIDONE": 14.851192660703886, "SPIRONOLACTONE": 15.522617916415909, "STOCRIN": 32.00288477148004, "TASIGNA": 1.6775482781585354, "TESTOSTERONE": 7.1351328836930366, "UROREC": 16.825726505283956, "XTANDI": 2.51981684479072, "ZYPREXA": 9.252248870444353, "null": 3.803797207469064}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3592.json
index 2b0e2e66b13..c1b492670e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3592.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3592.json
@@ -1 +1 @@
-{"CELLCEPT": 10.906384077074092, "CICLOSPORIN": 5.092930206166092, "INTELENCE": 147.18136326792742, "SYNAGIS": 26.584753479197943, "TAMIFLU": 108.54891770019869}
\ No newline at end of file
+{"ASPARAGINASE": 39.01901747401963, "QARZIBA": 3928.132134634512, "null": 0.2962512515197009}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3593.json
index f6054b9c4d4..8e750905198 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3593.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3593.json
@@ -1 +1 @@
-{"null": 2.6292082527673264}
\ No newline at end of file
+{"ADCIRCA": 16.910098237378843, "ADEMPAS": 6.592508650715661, "ALEMTUZUMAB": 2.4154903287578917, "ARAVA": 0.1152547439871855, "ASPARAGINASE": 2.736999805130599, "AVASTIN": 4.909805676757961, "BORTEZOMIB": 5.462717866926816, "BUSULFAN": 8.27454839435986, "CELLCEPT": 2.027763164724854, "CICLOSPORIN": 2.1677808868121344, "CIMZIA": 0.6617242479058768, "CINRYZE": 19.926846416457927, "COMIRNATY": 0.0197759505029248, "CUBICIN": 13.796878362177525, "CYTARABINE": 3.0422651673140653, "DOCETAXEL": 3.839835594120896, "ELIQUIS": 0.9418037358036928, "ENBREL": 0.9591369295158308, "ENTYVIO": 1.3643393987886063, "EXJADE": 4.365029135129989, "FORSTEO": 1.1944907559139308, "HUMALOG": 0.7945313763993431, "IBRANCE": 1.1635332891901038, "KEYTRUDA": 2.690611084579405, "LANTUS": 0.7327288224120209, "METHOTREXATE": 1.2263341359175886, "NAGLAZYME": 28.215620515878587, "OPSUMIT": 15.8848805205128, "OPTIMARK": 2.2342150366310363, "PEGASYS": 0.3141431089618569, "PRIVIGEN": 2.9931282403218487, "REVATIO": 4.758317415666881, "REVESTIVE": 208.10931976215815, "RITUXIMAB": 1.6641283120006096, "ROACTEMRA": 8.413927594355155, "RUCONEST": 30.379321726271023, "SIMPONI": 3.2504947018307058, "SOLIRIS": 18.367194571694, "SPINRAZA": 4.573279179665016, "STELARA": 0.97045227679257, "SUTENT": 0.7983096164174084, "TRACLEER": 10.561521861526485, "VFEND": 2.1858518328362457, "XELJANZ": 1.9256121720111825, "XTANDI": 1.9120429674887385, "null": 1.1497917149108916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3594.json
index b69d7c2c92a..ffdb714e289 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3594.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3594.json
@@ -1 +1 @@
-{"DOCETAXEL": 60.21118480566387, "HERCEPTIN": 100.46124334043576}
\ No newline at end of file
+{"BEDAQUILINE": 36.35403431090956, "BORTEZOMIB": 27.551091710468608, "CICLOSPORIN": 3.850231825075356, "MIDAZOLAM": 18.09276142727272, "OPSUMIT": 16.41062523312774, "SOLIRIS": 10.21334632086281, "TRACLEER": 13.396763461393135, "null": 0.9740902463907264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3595.json
index e112d76b5d3..ba8338c15ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3595.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3595.json
@@ -1 +1 @@
-{"ABACAVIR": 12.6857707366339, "AMINOSALICYLIC": 21.48713133078371, "BIKTARVY": 30.24915229169567, "DACLATASVIR": 94.41371560596392, "DARUNAVIR": 49.13240810702784, "DELAMANID": 69.40456006323075, "DESCOVY": 82.13567411867415, "EFAVIRENZ": 96.4603203157973, "EMTRICITABINE": 46.538992949554846, "ISENTRESS": 26.228616703695025, "KALETRA": 14.630431897388243, "LAMIVUDINE": 84.26817768120603, "NORVIR": 27.34268683994153, "STELARA": 6.786152554688027, "TRUVADA": 4.125121315088141, "VIAGRA": 4.956590106852047}
\ No newline at end of file
+{"ANGIOX": 252.83703855717584, "AVASTIN": 19.396066960536587, "ELIQUIS": 3.1957466969481545, "NOVOSEVEN": 73.5638634286628, "null": 1.1114042345463857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3596.json
index 1b0d7ddd47a..760e78ea8c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3596.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3596.json
@@ -1 +1 @@
-{"BIKTARVY": 41.80907631172655, "DESCOVY": 154.89261518741472, "EMTRICITABINE": 108.94046551656396, "KALETRA": 26.43780773610682, "STRIBILD": 8.126243426562583, "TRUVADA": 26.20451359067532, "VIAGRA": 15.282436861438102}
\ No newline at end of file
+{"null": 4.702219858979559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3597.json
index e29484084db..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3597.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3597.json
@@ -1 +1 @@
-{"BIKTARVY": 118.78717738244588, "DARUNAVIR": 657.6699485594878, "EFAVIRENZ": 118.22051711534051}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3598.json
index a16bc29d627..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3598.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3598.json
@@ -1 +1 @@
-{"ABACAVIR": 40.65245686934084, "BIKTARVY": 33.207019396040145, "COMBIVIR": 50.75525594379243, "EMTRICITABINE": 148.60740218812705, "LAMIVUDINE": 120.47572943055047}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3599.json
index a22bc449d66..207ba3ddc7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3599.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3599.json
@@ -1 +1 @@
-{"ENBREL": 123.61483817330104}
\ No newline at end of file
+{"null": 4.40329870614908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/36.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/36.json
index f15167a3cc5..d99046e46ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/36.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/36.json
@@ -1 +1 @@
-{"null": 3.9327400336564944}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/360.json
index 2a365b5fb8e..7b2a19f5cc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/360.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/360.json
@@ -1 +1 @@
-{"ABEMACICLIB": 2.4617573956389687, "ABRAXANE": 3.221139019553731, "ADCETRIS": 2.023261524132719, "ADCIRCA": 1.7821991639673351, "ADENURIC": 1.0479018886448264, "ADVAGRAF": 1.9075462164126025, "AFINITOR": 2.1570735096351243, "AFLIBERCEPT": 1.2171615470161363, "ALIGN": 7.573133338189613, "ALIMTA": 6.453276168811002, "AMBRISENTAN": 1.5038472798826732, "AMIKACIN": 1.9904688957772696, "AMINOSALICYLIC": 7.750340702567592, "ANAGRELIDE": 4.594814524997642, "ANIDULAFUNGIN": 2.371752324636192, "APREPITANT": 1.2954290597343914, "ARANESP": 8.111480776149696, "ARIXTRA": 7.857211504725206, "ARZERRA": 2.4003178637361526, "ATAZANAVIR": 1.1743306869648844, "ATEZOLIZUMAB": 4.566416776386276, "AVAMYS": 2.005749835707711, "AVANDIA": 1.213888507193279, "AVASTIN": 2.283798329725504, "AVELUMAB": 1.7276306277029168, "AXICABTAGENE": 1.5327489997470527, "AZACITIDINE": 6.562574264637725, "AZATHIOPRINE": 1.37841032356793, "BAVENCIO": 1.1299991332980404, "BEDAQUILINE": 5.101418975562086, "BEVACIZUMAB": 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\ No newline at end of file
+{"COMIRNATY": 0.3193169035832338, "null": 1.1729573337094923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3600.json
index 958942651d2..604703bd3a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3600.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3600.json
@@ -1 +1 @@
-{"null": 1.4952445862083286}
\ No newline at end of file
+{"null": 0.8452258041202194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3601.json
index c86735e5d62..3de04f0036b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3601.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3601.json
@@ -1 +1 @@
-{"COVID19": 14.095700905477258}
\ No newline at end of file
+{"AIMOVIG": 11.107103303147468, "AZILECT": 64.0807080143582, "FORSTEO": 3.779206077775167, "INCRUSE": 32.54899279044496, "NEULASTA": 65.49996930188465, "TRELEGY": 15.651119439082423, "null": 4.71589838019512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3602.json
index 503d596fbec..07d21d848a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3602.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3602.json
@@ -1 +1 @@
-{"ABILIFY": 3.315247620901477, "ASPARAGINASE": 22.35483115503358, "ELIQUIS": 1.1015019096267098, "GARDASIL": 1.8014067267425162, "KEPPRA": 2.534742271829902, "LEVETIRACETAM": 7.876656868223224, "SUTENT": 1.0451806666739438, "null": 1.2800597492570676}
\ No newline at end of file
+{"AIMOVIG": 2.616640156045007, "APIDRA": 9.379510516285418, "BYDUREON": 11.178510262233177, "BYETTA": 3.625350070257985, "EYLEA": 217.29945487963525, "FASENRA": 28.51250633612801, "INSULIN": 6.404554118369118, "LANTUS": 10.727291029827503, "SIMPONI": 6.14041394171742, "null": 2.507346764846396}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3603.json
index 19590054608..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3603.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3603.json
@@ -1 +1 @@
-{"null": 3.308970672206197}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3604.json
index b8ebc13c537..6dede4261ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3604.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3604.json
@@ -1 +1 @@
-{"JANUMET": 65.89959829726607}
\ No newline at end of file
+{"DEXAMETHASONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3605.json
index 8334fdf0c67..5f197cf68ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3605.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3605.json
@@ -1 +1 @@
-{"ESMYA": 99.47312502887094, "JANUMET": 12.137489227834823, "JANUVIA": 10.909889206594755, "PEGASYS": 3.0180354213133453}
\ No newline at end of file
+{"null": 4.383662583052356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3606.json
index d97632c8e53..0c29b1dfc61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3606.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3606.json
@@ -1 +1 @@
-{"COSENTYX": 12.872230297427013, "COVID19": 1.093473201458313, "ZOSTAVAX": 9.083401029576477}
\ No newline at end of file
+{"null": 3.024396352504493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3607.json
index 32f8f14b415..e485ccdaf65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3607.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3607.json
@@ -1 +1 @@
-{"ABACAVIR": 1.3585166951423695, "ADVATE": 667.7554723400546, "BRILIQUE": 2.929651493849026, "CLOPIDOGREL": 2.2725792155679425, "EFAVIRENZ": 5.062523552540863, "ELIQUIS": 8.364239985396967, "ELOCTA": 389.0320415415492, "EMICIZUMAB": 371.1927162278088, "ENOXAPARIN": 4.93098580283302, "HELIXATE": 316.6600559403955, "HEMLIBRA": 398.94422635045646, "JAKAVI": 1.590850540375606, "JIVI": 651.8662961820921, "KOGENATE": 316.6545819566622, "KOVALTRY": 1441.2948583006842, "LIXIANA": 11.77876017032896, "NOVOSEVEN": 42.15458499907231, "PLAVIX": 3.708443549757176, "XARELTO": 13.211687972133172, "null": 2.2772461758699483}
\ No newline at end of file
+{"LEVEMIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3608.json
index 24d0bf65747..195aaa67106 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3608.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3608.json
@@ -1 +1 @@
-{"ADCIRCA": 2.932943338279294, "ADVATE": 3.758937820757549, "APIXABAN": 1.3709666664051314, "APREPITANT": 7.128921403952469, "ARIXTRA": 15.211714430613116, "AVASTIN": 1.7838891135560386, "BLINCYTO": 9.986197655076232, "BONVIVA": 1.1894719011955766, "BRILIQUE": 7.436814392953587, "BYDUREON": 1.1970267856323542, "CELECOXIB": 1.1140510906379293, "CHAMPIX": 1.7216453576841146, "CLOPIDOGREL": 26.56258282486024, "DAKLINZA": 2.381789854589192, "EFIENT": 4.722089718182537, "ELIQUIS": 5.286726837040084, "ENOXAPARIN": 9.689882629833724, "EPCLUSA": 1.842330260371689, "EPIVIR": 1.2565573003669126, "EVEROLIMUS": 2.177070177769392, "EXJADE": 2.00155343878844, "EXVIERA": 2.2427581704836985, "HARVONI": 1.756626094114944, "IBUPROFEN": 3.165175977949407, "INLYTA": 1.3253998583368134, "INTEGRILIN": 15.604528776443608, "INVOKANA": 1.897025212537233, "IRESSA": 1.1012545556607396, "ISCOVER": 20.048102492198485, "JAKAVI": 1.0908727888721603, "LENVIMA": 2.762349110647884, "LIXIANA": 4.907429352664151, "LONSURF": 1.1245940092536664, "NEXAVAR": 4.566180596194154, "OLYSIO": 1.7337573631948535, "PEGASYS": 2.233979819319233, "PEGINTRON": 1.3119158700795748, "PLAVIX": 17.439718897034922, "PRADAXA": 7.3812379416437315, "RIBAVIRIN": 1.6992589425835656, "RIVAROXABAN": 3.800712710131725, "ROTATEQ": 2.192814698861416, "SAXENDA": 1.390811811486339, "SOVALDI": 3.071148194505439, "SPINRAZA": 1.4003232014423557, "SPIRONOLACTONE": 1.861441409670986, "STIVARGA": 1.8164136257631764, "SUBOXONE": 1.0339872401002117, "SUTENT": 3.158565124587331, "TAMIFLU": 3.663986805918873, "TICAGRELOR": 32.75904461306297, "TRULICITY": 1.3690518063446258, "VICTOZA": 1.0411457102526582, "VOTRIENT": 1.7675056533815108, "XARELTO": 7.784884223034125, "null": 1.4292244744442273}
\ No newline at end of file
+{"COMIRNATY": 0.1493859086683894, "DEXAMETHASONE": 2.220574815097564, "FENTANYL": 3.2195780428567287, "JARDIANCE": 1.3379754472131211, "KEYTRUDA": 1.3058202148199838, "MIDAZOLAM": 10.1106456392921, "OLANZAPINE": 3.785209630940964, "RELVAR": 16.066569472745726, "TEMOZOLOMIDE": 61.41906402176815, "VAXZEVRIA": 0.0871095585795783, "VFEND": 3.328160182644789, "ZYPREXA": 3.4326556602616947, "null": 2.751687553479084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3609.json
index 4b91202af36..aa4a51dde5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3609.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3609.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.3904797833235825, "ADEMPAS": 1.171804099525028, "ALIGN": 34.126519537307274, "AMINOSALICYLIC": 19.042815628925773, "APIXABAN": 1.2305618493848698, "AVAMYS": 9.190147581552017, "AZATHIOPRINE": 1.2140081416556143, "BEVACIZUMAB": 1.0737953834835514, "BEXSERO": 4.255025238763068, "BRAFTOVI": 2.506617132214196, "BRILIQUE": 2.9546280004633725, "BUDESONIDE": 13.371931013562667, "CHAMPIX": 2.172045734848657, "CLOPIDOGREL": 13.645708397845585, "COSENTYX": 2.2197076841544248, "COTELLIC": 1.0615560396242416, "DEFITELIO": 5.002377133548935, "EFIENT": 2.631665290067257, "ELIQUIS": 6.178089556178612, "ENOXAPARIN": 5.168128853245664, "ENTYVIO": 11.757112570471056, "EXJADE": 1.5405875723861824, "HUMIRA": 3.02475368462139, "IBUPROFEN": 1.4341316430806414, "INFANRIX": 6.56523801738394, "INFLECTRA": 10.800432444208164, "INFLIXIMAB": 6.751309300719136, "IRINOTECAN": 1.0480368176849015, "LEFLUNOMIDE": 1.8390851922071532, "LIXIANA": 7.792203544167881, "LONSURF": 1.480505872965729, "MERCAPTOPURINE": 1.1161303534210796, "NEXAVAR": 2.065175509226473, "NOT": 1.1216947632550502, "OCALIVA": 1.6074427890777925, "OFEV": 1.5920422922600508, "PEGASYS": 1.3189211853290337, "PLAVIX": 7.555389457139873, "PRADAXA": 5.525551301341769, "PREGABALIN": 5.211406089267794, "PREVENAR": 13.089426427898417, "REMICADE": 3.4020450664099515, "REMSIMA": 22.43208258586061, "REVATIO": 1.0398237512916422, "RINVOQ": 1.306022139784549, "ROTARIX": 30.082022344830197, "ROTATEQ": 73.02097858188027, "SILDENAFIL": 1.1008942687337102, "SIMPONI": 1.550604459795872, "SPRYCEL": 2.25613447702314, "STELARA": 3.0657996835981964, "STIVARGA": 1.75917330968232, "SUTENT": 2.6888837016044844, "SYNAGIS": 1.754852960609634, "TAMIFLU": 1.308349815653396, "TICAGRELOR": 17.490500659589728, "VEDOLIZUMAB": 9.751189704630647, "VELTASSA": 2.6906271494039675, "VOTRIENT": 1.872519488374397, "XARELTO": 4.947048110993616, "XELJANZ": 8.015235406559377, "YERVOY": 1.432959158637351}
\ No newline at end of file
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1.4561596614079175, "REYATAZ": 2.6803133827910326, "RIBAVIRIN": 1.914912012107828, "RINVOQ": 0.2389623976749951, "RITUXIMAB": 1.223278490062645, "ROACTEMRA": 0.2259657381999973, "SAXENDA": 0.3515518773937767, "SHINGRIX": 0.1190394450116748, "SIGNIFOR": 29.916075994128832, "SIMPONI": 0.9474036999187484, "SITAGLIPTIN": 7.759073765927343, "SKYRIZI": 1.174500248971416, "SOLIRIS": 0.367479740708597, "SOMATROPIN": 5.843430255987122, "SPIKEVAX": 0.0783336206078326, "SPRYCEL": 0.5943251133232624, "STELARA": 1.2983975659914344, "SUBOXONE": 0.4065049966065161, "SUTENT": 1.041383521098492, "TACROLIMUS": 1.9984429643089583, "TAMIFLU": 0.1796199264992455, "TASIGNA": 5.09492732077336, "TIVICAY": 1.7194649012297687, "TORISEL": 3.2700989986205378, "TOUJEO": 0.5838621376737267, "TOVIAZ": 1.7188878585518477, "TOZINAMERAN": 0.2704313707422319, "TRACLEER": 0.2163314683160083, "TRELEGY": 2.336604930260296, "TREMFYA": 1.07654055057984, "TRIUMEQ": 2.7495817701500176, "TRULICITY": 0.8096975681578419, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/361.json
index 2b813ae0b85..9f29af4ad53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/361.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/361.json
@@ -1 +1 @@
-{"null": 1.037905549454037}
\ No newline at end of file
+{"ABILIFY": 0.8485113526906966, "AIMOVIG": 0.6201183249040789, "ALISKIREN": 133.0812008876443, "ARAVA": 0.1006695950148808, "ARIPIPRAZOLE": 2.742677277780885, "ATRIPLA": 0.1290565006413828, "BEDAQUILINE": 2.762911713375732, "BIKTARVY": 1.8642262426464216, "BRINTELLIX": 0.9751414433233166, "CHAMPIX": 6.418778886144247, "COMIRNATY": 0.1616506162182692, "COMTAN": 3.74923040719733, "COSENTYX": 0.4201505171680688, "CYMBALTA": 98.92343627003233, "ELIQUIS": 0.2733206442233619, "ESOMEPRAZOLE": 4.142142297541798, "GARDASIL": 0.6221498189931012, "INTRONA": 10.212844626797075, "IRBESARTAN": 2.239939030146136, "KAFTRIO": 2.645001303995736, "KEPPRA": 4.1838055624258015, "LATUDA": 1.5390596350379446, "LEVETIRACETAM": 5.242873019592547, "LURASIDONE": 25.37238668375416, "OLANZAPINE": 3.423857609458621, "PEGASYS": 1.6533594100786904, "PEGINTERFERON": 1.4846194152889176, "PEGINTRON": 2.0667101406331296, "RIBAVIRIN": 1.336143363829667, "SPIKEVAX": 0.0683319547422719, "TOZINAMERAN": 0.114500656705167, "VAXZEVRIA": 0.0750378228837507, "ZYPREXA": 2.343477978976052, "null": 0.8891907755282443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3610.json
index cdb72d0428d..fd2b56795b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3610.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3610.json
@@ -1 +1 @@
-{"ADENURIC": 84.86288409180669, "JAKAVI": 17.441802451416223, "PEGASYS": 5.25921771551082, "SOLIRIS": 22.55126218028763}
\ No newline at end of file
+{"ABASAGLAR": 13.576814997310883, "ABILIFY": 0.4399401784259326, "ACTOS": 10.31135478235812, "ACTRAPID": 11.34641026278777, "AFINITOR": 0.542347708406441, "ALISKIREN": 16.349722221540553, "AMINOSALICYLIC": 0.3784561722419604, "APIDRA": 35.974658050973474, "ARAVA": 0.0381509649176078, "AVANDAMET": 1.564686814534568, "AVANDIA": 1.4837767990141058, "AZATHIOPRINE": 0.6334512926367205, "BYDUREON": 3.0743956480097707, "BYETTA": 7.847008794553672, "CELLCEPT": 0.4644812310252676, "CHAMPIX": 0.5830104013529168, "CICLOSPORIN": 0.1781966622503129, "COMIRNATY": 0.085014059281769, "CORTICOSTEROID": 10.698443351435952, "COSENTYX": 0.1622041641849925, "CYMBALTA": 0.2535897678330054, "DAPAGLIFLOZIN": 20.027312144058687, "DENOSUMAB": 2.9057128299904025, "DULAGLUTIDE": 10.528916639845542, "ELIQUIS": 0.094281052734565, "EMPAGLIFLOZIN": 3.97884509518968, "ENBREL": 0.6405838129655249, "ENTRESTO": 0.2574795566158622, "EUCREAS": 6.844122069330457, "EXFORGE": 0.93297094791347, "FIASP": 16.217478184626113, "FORXIGA": 4.799021988636817, "GALVUS": 9.679251838798468, "GLIBENCLAMIDE": 8.447044086679902, "HUMALOG": 14.300533916613396, "INSULATARD": 45.73221546366466, "INSULIN": 31.43320458273843, "INSUMAN": 21.62515435482284, "INVOKANA": 9.360549912086556, "ISOPHANE": 7.786595303256626, "JANUMET": 22.947629134094043, "JANUVIA": 19.180688467661472, "JARDIANCE": 2.0681714406599188, "KAFTRIO": 1.0109286689254715, "KEYTRUDA": 0.4104921598004624, "LANTUS": 34.88072388199223, "LEVEMIR": 28.45059011529621, "LIRAGLUTIDE": 17.796183174987, "LYRICA": 0.2787461611033128, "METFORMIN": 46.19856862577995, "METHOTREXATE": 0.187542606365115, "MIXTARD": 24.90666304953643, "NOVOMIX": 38.6016981657808, "NOVONORM": 16.849524671917386, "NOVORAPID": 22.64957451594024, "OMALIZUMAB": 1.380649873356215, "OPTISULIN": 140.78213247575314, "PASIREOTIDE": 15.64736701682251, "PEGASYS": 0.2786806154002789, "PEGINTRON": 0.266438520994718, "PLAVIX": 0.1109031479190055, "RITUXIMAB": 0.319272310017166, "ROSIGLITAZONE": 8.764515565412617, "RYBELSUS": 7.756962584571959, "SITAGLIPTIN": 24.894974495762845, "SPIKEVAX": 0.0945989116949717, "STELARA": 0.2740122444156337, "SUTENT": 0.1396954689479124, "TASIGNA": 0.5081696961228629, "TOUJEO": 73.25068238530734, "TOZINAMERAN": 0.0730750228193822, "TRESIBA": 27.952348195969947, "TRULICITY": 6.013370393474809, "VAXZEVRIA": 0.0574463630032552, "VIAGRA": 0.5086071906621625, "VICTOZA": 11.583798439941091, "VILDAGLIPTIN": 17.407003863466525, "XELJANZ": 0.1528101864132501, "ZOSTAVAX": 1.329021317066349, "ZYPREXA": 2.2571293419371847, "null": 0.5684140067105075}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3611.json
index 1ae5ad6d3e9..53a90150e33 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3611.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3611.json
@@ -1 +1 @@
-{"ABATACEPT": 1.3305842520864763, "ABILIFY": 2.4875027140086776, "ACTRAPID": 2.8540721932572395, "ADALIMUMAB": 1.6439359262958386, "ADCIRCA": 2.7382750792997625, "ADENURIC": 3.660531441984818, "AFINITOR": 2.985292321842172, "ALEMTUZUMAB": 2.845809387099111, "ALIMTA": 2.4102747656145813, "AMIKACIN": 3.892416527627805, "ARANESP": 2.703816192310017, "ARIPIPRAZOLE": 1.796258805674277, "AVANDIA": 1.0938518771546426, "BEDAQUILINE": 3.288530461342508, "BEVACIZUMAB": 2.7721037922102703, "BRILIQUE": 4.875630443506753, "CASPOFUNGIN": 10.08771034552078, "CELLCEPT": 1.293439142154509, "CICLOSPORIN": 2.058880996940464, "CLOPIDOGREL": 2.103426154553095, "COMBIVIR": 1.456046700953546, "COMTAN": 3.7899886212270286, "CYTARABINE": 1.025470761923451, "DOCETAXEL": 1.9509479308719464, "ELIQUIS": 1.2060303565148325, "ENOXAPARIN": 3.240007182005958, "ENTRESTO": 3.153285875838852, "EPOETIN": 9.229948820867802, "ESOMEPRAZOLE": 2.2959368742897643, "EVISTA": 2.5157855363644157, "EXJADE": 13.433071136717013, "FENTANYL": 1.2419990423476648, "FORSTEO": 1.0892325036665724, "FULVESTRANT": 4.667494169906409, "GLIVEC": 3.902234984905897, "IBRANCE": 4.237997329274284, "ICLUSIG": 2.0211491628069385, "INCIVO": 2.9023747322074533, "INTEGRILIN": 8.535036944170484, "JAKAVI": 10.46136745343274, "KISQALI": 5.334721197358444, "KYMRIAH": 4.583176079809899, "LEMTRADA": 5.632492966493451, "LYNPARZA": 1.9378452475624448, "MEKINIST": 1.3225791297918756, "METFORMIN": 10.207662634458815, "METHOTREXATE": 1.1752115092279969, "MICARDIS": 1.243233939348589, "MIRCERA": 9.02569323503856, "NALOXONE": 15.3371753997248, "NEULASTA": 1.1883835569147705, "OPSUMIT": 3.691477820664484, "PEGASYS": 6.866375065843592, "PEGINTERFERON": 1.3631338147087186, "PEGINTRON": 2.933802179443729, "PLAVIX": 3.330966251613269, "RASILEZ": 1.909502518774794, "RIBOCICLIB": 4.957351605025616, "RINVOQ": 2.144471334451928, "RUBRACA": 5.8683464905226925, "RUXOLITINIB": 11.088714795018666, "SOLIRIS": 10.356739423965822, "SOVALDI": 1.749998386933592, "SUTENT": 1.693058231841795, "TASIGNA": 2.5115994343114387, "TRACLEER": 4.185402766710015, "XARELTO": 1.3588533997835848, "XELJANZ": 1.0555535013438129, "ZIAGEN": 5.334144563589491, "ZOMETA": 6.303005249763632, "ZYPREXA": 1.4204188199739347, "null": 1.2870400020399098}
\ No newline at end of file
+{"FORXIGA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3612.json
index 897f90fd5ce..e0b7b72a73b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3612.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3612.json
@@ -1 +1 @@
-{"EMPAGLIFLOZIN": 65.15206964147711, "FORXIGA": 15.745149589955863, "GONALF": 51.5815769560383, "JAKAVI": 25.10358107547944, "JARDIANCE": 51.86051337387845, "OLANZAPINE": 2.2046835363884574, "ORGALUTRAN": 161.93228765978904, "null": 1.203831960746889}
\ No newline at end of file
+{"null": 0.4335501018639234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3613.json
index 62e67d04187..ae399590539 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3613.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3613.json
@@ -1 +1 @@
-{"SPIKEVAX": 20.527430928801905}
\ No newline at end of file
+{"HUMALOG": 85.28995832096584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3614.json
index 8ec6cfb7146..8dc0e169038 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3614.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3614.json
@@ -1 +1 @@
-{"NPLATE": 89.06962410391, "null": 2.1703606170079426}
\ No newline at end of file
+{"ACTRAPID": 58.117475163788185, "APIDRA": 16.645109223420803, "FORXIGA": 6.198909028747671, "HUMALOG": 28.602296636416888, "INSULIN": 11.618656415187392, "JARDIANCE": 5.370623760899034, "LANTUS": 19.47825748209545, "LEVEMIR": 23.694001794678336, "MIXTARD": 46.458681894083526, "NOVORAPID": 4.532084741376102, "OLANZAPINE": 1.589347418267715, "PEGINTRON": 1.5882993847639575, "ZYPREXA": 49.46844437744479, "null": 0.5807440916360909}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3615.json
index 722e9dda9ce..114db263dc9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3615.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3615.json
@@ -1 +1 @@
-{"PEGASYS": 8.399116914428886, "SOLIRIS": 36.99931267664951}
\ No newline at end of file
+{"AVANDIA": 3.221978887693275, "HUMALOG": 35.374853890799834, "INSULIN": 21.55803787907776, "JANUMET": 49.56541672776076, "JANUVIA": 40.179247410170674, "JARDIANCE": 1.826247114847138, "LANTUS": 15.236667187704, "LEVEMIR": 15.97055975674308, "TRULICITY": 6.540771285488041, "ZOSTAVAX": 1.9198728914889955, "ZYPREXA": 3.612306794849199, "null": 0.5882425681600552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3616.json
index 8555676e2cb..06a2b43adac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3616.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3616.json
@@ -1 +1 @@
-{"ADVATE": 11.980213383208149, "ANGIOX": 7.602528803716543, "APREPITANT": 2.2415298008861395, "ARIXTRA": 41.13495550792344, "BRILIQUE": 13.610425515700634, "BRINTELLIX": 2.219768101709217, "CLOPIDOGREL": 6.404229353443926, "COMTAN": 1.479920387109966, "DUOPLAVIN": 10.158495994559376, "EFIENT": 12.07766677869722, "ELIQUIS": 9.631491425366338, "ENOXAPARIN": 13.792405347287277, "EPTIFIBATIDE": 15.381040860995212, "FORSTEO": 1.1113624203194523, "GREPID": 11.971011002331942, "HEMLIBRA": 10.673501489683895, "IMBRUVICA": 2.689876820169475, "INHIXA": 23.664258543389558, "INTEGRILIN": 10.763089054217128, "ISCOVER": 12.559726952073577, "JAKAVI": 2.664438045667437, "LEMTRADA": 1.2381663575766244, "LIXIANA": 11.008780161986602, "NOVOSEVEN": 6.861519736742956, "NPLATE": 1.2495825025958345, "PLAVIX": 8.820475291757107, "PRADAXA": 7.574085092707243, "PRASUGREL": 14.338691378773008, "RIVAROXABAN": 1.7970381251161394, "ROACTEMRA": 1.7205893843478082, "RUXOLITINIB": 2.144443065236377, "TICAGRELOR": 3.075330957252272, "VAXZEVRIA": 1.7665151783781348, "XARELTO": 9.002013364122046, "XIAPEX": 29.5885108338494, "null": 1.6588328323026256}
\ No newline at end of file
+{"CIMZIA": 10.135841020808693, "HUMALOG": 32.44686482396717, "LANTUS": 11.683414066951183, "null": 0.6713187589256207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3617.json
index d1bf86931ec..a682e2148cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3617.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3617.json
@@ -1 +1 @@
-{"ELIQUIS": 34.913481656251, "null": 1.3433078838348391}
\ No newline at end of file
+{"ACTRAPID": 22.56599025086869, "EMPAGLIFLOZIN": 33.98247064535207, "EXFORGE": 4.855677195260501, "FORXIGA": 6.831279838303735, "HUMALOG": 23.947018248427177, "INSULIN": 27.46926848560356, "INVOKANA": 349.4085678851333, "JARDIANCE": 13.554041733083196, "LANTUS": 14.294896994504413, "LEVEMIR": 20.342181416544825, "MICARDIS": 7.003120379896103, "MIXTARD": 85.83869103505633, "NOVORAPID": 7.204820993085825, "VAXZEVRIA": 0.0625738431129526, "ZOSTAVAX": 2.1622474118318986, "ZYPREXA": 2.969149638576205, "null": 0.5973680882551614}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3618.json
index 30073b71b38..a058cca255c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3618.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3618.json
@@ -1 +1 @@
-{"ADVATE": 23.95071289970571, "ARIXTRA": 75.38139348792014, "BRILIQUE": 11.425673710578712, "CLOPIDOGREL": 11.336636315875763, "ELIQUIS": 12.607735570857788, "ENOXAPARIN": 48.88352752084599, "HEMLIBRA": 32.78587640673578, "JAKAVI": 2.372715717867313, "LIXIANA": 6.914985491947554, "PLAVIX": 9.283363490721277, "TAMIFLU": 1.8793458866975568, "XARELTO": 16.142705403003053, "null": 3.43351140776761}
\ No newline at end of file
+{"HUMALOG": 12.7728041407869, "INVOKANA": 1113.6493314067463, "JARDIANCE": 8.243405999302322, "LANTUS": 5.339330076431342, "null": 0.3927984189080954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3619.json
index 4351a7d9c6f..6c03e2381a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3619.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3619.json
@@ -1 +1 @@
-{"COVID19": 1.0299307299218572, "ELIQUIS": 3.9188670101785488, "VIAGRA": 56.93989320388568}
\ No newline at end of file
+{"HUMALOG": 21.283079157421508, "null": 0.30060044783016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/362.json
index 7793fdc0ad0..c5edef39ed7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/362.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/362.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 2.3477833114373263, "COMBIVIR": 90.36771396112262, "ELIQUIS": 2.254918277813063, "EPIVIR": 20.41601545663509, "ESOMEPRAZOLE": 10.613359171990984, "IBRANCE": 3.4056776782367724, "KALETRA": 5.241832436686096, "PEGASYS": 4.5229869174040775, "PEGINTRON": 2.887803207817908, "PLAVIX": 1.7018587546849968, "null": 1.1647632009824844}
\ No newline at end of file
+{"ARIPIPRAZOLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3620.json
index 89ebf34627f..a63b4e884a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3620.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3620.json
@@ -1 +1 @@
-{"AFINITOR": 1.6643536007765445, "ALIMTA": 18.18047000409302, "ASPARAGINASE": 39.7439864866309, "AUTOLOGOUS": 900.225238050385, "AVASTIN": 6.31299408667928, "AZACITIDINE": 45.96069004427152, "BEVACIZUMAB": 25.053561642717888, "BORTEZOMIB": 5.014086440832481, "BUSULFAN": 1.9364870560440128, "CAELYX": 12.74634902097489, "CAPECITABINE": 15.038631744374356, "CARFILZOMIB": 6.904265484684573, "CARMUSTINE": 91.91135750287236, "CELLCEPT": 1.944483526863083, "CETUXIMAB": 22.83093732451928, "CLADRIBINE": 13.235147303194593, "CYTARABINE": 8.532628794068346, "DARATUMUMAB": 27.306766249685985, "DARZALEX": 6.67487551328717, "DEXAMETHASONE": 4.177160855861352, "DOCETAXEL": 16.664863617161, "DOXORUBICIN": 7.817870414904575, "FASLODEX": 1.3369388333647625, "FULVESTRANT": 9.399724061338697, "GLIVEC": 7.928366869414983, "HYCAMTIN": 19.74903657799025, "IBRANCE": 3.340843349312578, "ICLUSIG": 12.952161655373692, "IMATINIB": 20.50221729377359, "IRINOTECAN": 32.65306852212763, "JAKAVI": 3.142326186994431, "JEVTANA": 10.568738710373212, "KEYTRUDA": 1.9766475332106173, "KISQALI": 9.52389482859843, "LONSURF": 7.130697356303676, "LOPINAVIR": 16.872814125327896, "LUTATHERA": 30.436555517539382, "LUTETIUM": 53.23100045612008, "LYNPARZA": 20.231247227822493, "METHOTREXATE": 2.695406933591852, "NEXAVAR": 1.7594670637644805, "NILOTINIB": 26.942674821013792, "OBINUTUZUMAB": 12.510331163226136, "OLAPARIB": 31.78129426960385, "PACLITAXEL": 15.127491562013253, "PEMBROLIZUMAB": 4.317666568753709, "PEMETREXED": 59.72475605556156, "RIBOCICLIB": 19.478325362592496, "RITUXIMAB": 7.216792466840529, "RUBRACA": 4.10209729463261, "SORAFENIB": 11.741519357162655, "SPRYCEL": 4.18291779009479, "SUTENT": 2.266911024615205, "TAGRISSO": 2.965636279316429, "TASIGNA": 5.449363736664067, "TEMODAL": 6.996148203447115, "TEMOZOLOMIDE": 55.01334121756218, "THIOTEPA": 34.0783825233434, "TOPOTECAN": 14.682500968407506, "TRODELVY": 8.106610741968414, "VECTIBIX": 20.76880639419742, "VENETOCLAX": 30.873930476153586, "XOFIGO": 21.636823630609022, "YONDELIS": 27.102429169140475}
\ No newline at end of file
+{"HUMALOG": 21.03276600434173, "null": 0.5314048218847349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3621.json
index 018e7b9b589..273819536a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3621.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3621.json
@@ -1 +1 @@
-{"ADENURIC": 1.80872516647527, "ADVATE": 2.94461079396561, "ALEMTUZUMAB": 1.642687367327516, "ARIXTRA": 6.903668053939697, "ATAZANAVIR": 2.4877349703466427, "AVASTIN": 1.719086240610965, "AVELUMAB": 2.679155157518853, "BARACLUDE": 1.4511480179776202, "BASILIXIMAB": 4.774283069027482, "BETMIGA": 1.814884890044833, "BEVACIZUMAB": 1.6398104882390545, "BRILIQUE": 16.454834224014114, "BUSILVEX": 4.311988840851732, "BUSULFAN": 3.247005184692256, "CABAZITAXEL": 12.222986977602348, "CANCIDAS": 2.5261554531428003, "CELLCEPT": 1.378551879131662, "CICLOSPORIN": 3.088571850930101, "CIDOFOVIR": 4.976482507869688, "CLOPIDOGREL": 10.301576385550746, "COAPROVEL": 1.5067966471993837, "CRIXIVAN": 13.637626111973487, "DEFITELIO": 7.7623825337670675, "DOXORUBICIN": 1.0098142636211265, "EFIENT": 5.847139049660059, "ELIQUIS": 10.86217903547569, "ENOXAPARIN": 8.627198188519179, "ENZALUTAMIDE": 4.770931430403489, "ERLEADA": 1.4304417273466978, "ESOMEPRAZOLE": 1.0585063718639625, "EXJADE": 1.504293213993584, "FORXIGA": 3.8979238657451742, "HEMLIBRA": 5.609204308743358, "INLYTA": 1.3716692262441477, "INTEGRILIN": 9.858123716136872, "IRBESARTAN": 2.768685900823205, "IRESSA": 2.656481204132464, "ISCOVER": 4.93785051987726, "JARDIANCE": 2.5647124553755, "JEVTANA": 8.131462164610689, "KALETRA": 1.4764241193560972, "LEMTRADA": 1.5218267680967317, "LENVIMA": 1.1712228258461164, "LIXIANA": 22.550060663647884, "LONSURF": 1.5117947042823712, "METHOTREXATE": 1.6202892971566925, "MIDAZOLAM": 1.1542604069199165, "NEXAVAR": 1.008038744288465, "NORVIR": 1.8761482059664207, "NOVOSEVEN": 6.422925631293882, "NPLATE": 1.9827945280471169, "PLAVIX": 12.126307237353275, "PRADAXA": 8.11327325955491, "PRASUGREL": 7.953078222226222, "PRAXBIND": 6.530516502713406, "REYATAZ": 2.217126970452264, "RIVAROXABAN": 4.782536841380658, "SOLIRIS": 2.580322675520116, "SPINRAZA": 1.8909073419988127, "SPIRONOLACTONE": 2.502485500229438, "STIVARGA": 1.7205693085373146, "SUTENT": 2.0475593433120958, "TAMIFLU": 2.1216630045715763, "TELMISARTAN": 1.4897959211284113, "TICAGRELOR": 9.169292620862317, "TOPOTECAN": 2.766400653094257, "TORISEL": 1.3667753045856026, "VIAGRA": 1.1621223364077533, "VOTRIENT": 1.3571115331720502, "XARELTO": 19.47667888848008, "XOFIGO": 1.8010753143403655, "XTANDI": 2.0918382320871345, "null": 1.546984966178842}
\ No newline at end of file
+{"ACTRAPID": 121.4428010700712, "APIDRA": 14.602489118335557, "HUMALOG": 22.07770547213865, "LANTUS": 38.24427610250972, "LEVEMIR": 30.03849825117936, "NOVORAPID": 39.16761393407517, "ZYPREXA": 6.794034007900975, "null": 0.4548232112004773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3622.json
index 241daaf79ba..bd1101405e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3622.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3622.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 15.673936098548204, "ELIQUIS": 9.057287006545344, "LENVIMA": 47.64103992779931, "NEXAVAR": 55.40618228772155, "PLAVIX": 8.634130011881549}
\ No newline at end of file
+{"ZYPREXA": 75.06022336659977, "null": 0.66986475727257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3623.json
index 281b2f6c7f0..fe9fb53e246 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3623.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3623.json
@@ -1 +1 @@
-{"ARAVA": 1.8455347883976427, "EXJADE": 47.9677763047148, "PEGASYS": 8.25056931707855}
\ No newline at end of file
+{"LANTUS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3624.json
index a4215b06947..58d06c21105 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3624.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3624.json
@@ -1 +1 @@
-{"null": 2.650056585819588}
\ No newline at end of file
+{"ABASAGLAR": 1.1122511686741627, "ABILIFY": 0.6898807232044323, "ACTOS": 9.56926879566681, "ACTRAPID": 6.956915140463213, "ALPELISIB": 13.721487383478536, "APIDRA": 10.413709749129318, "ASPARAGINASE": 1.0586983683101294, "AVANDIA": 0.2184493379317073, "BIKTARVY": 0.4871241958065356, "BYDUREON": 2.033536944682869, "BYETTA": 2.107470548018147, "CANAGLIFLOZIN": 29.193034745197984, "CELLCEPT": 0.5224875243632044, "COMIRNATY": 0.0321099408795258, "CRIXIVAN": 3.283379577189858, "CYMBALTA": 0.1374711190600525, "DAPAGLIFLOZIN": 25.858499878737284, "DEXAMETHASONE": 0.1922886239087454, "DULAGLUTIDE": 9.271060300581452, "EMPAGLIFLOZIN": 89.44592024531175, "EUCREAS": 1.7501453058857843, "FASLODEX": 0.2367846526982863, "FIASP": 14.355386403881882, "FORXIGA": 50.11387989588625, "GARDASIL": 0.1167060399462579, "GLUCAGON": 4.34660284657334, "HUMALOG": 19.349638678136333, "HYDROCORTISONE": 0.4478068480120564, "INSULATARD": 8.997746470177342, "INSULIN": 11.00095644272016, "INVIRASE": 4.30234548388804, "INVOKANA": 245.70819420025737, "IPILIMUMAB": 6.098810213645955, "JANUMET": 1.2376225987678722, "JANUVIA": 1.2586834447165451, "JARDIANCE": 129.5106885467754, "KEYTRUDA": 3.359872781936551, "LANTUS": 7.140274082965632, "LATUDA": 0.6125843260613094, "LEVEMIR": 18.386146715658228, "MIXTARD": 27.385474127679416, "NOVOMIX": 12.350700832129338, "NOVORAPID": 46.17738404370029, "OLANZAPINE": 2.634120208353456, "OPDIVO": 3.257024816621925, "PEGASYS": 0.4879967154536918, "PEGINTERFERON": 0.8332241359005821, "PEGINTRON": 1.8813537216188931, "PEMBROLIZUMAB": 5.312034656407763, "PIQRAY": 18.280216893171648, "RYBELSUS": 3.628025515103677, "SPIKEVAX": 0.0389922789960617, "SUBOXONE": 0.2022738183625117, "TOUJEO": 3.78987716326205, "TOZINAMERAN": 0.0816400526190419, "TRESIBA": 16.452381771478876, "TRULICITY": 4.007679780105471, "VAXZEVRIA": 0.0327760591001215, "VICTOZA": 4.578287595840591, "ZYPREXA": 9.708810155299544, "null": 0.1826319016090404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3625.json
index 2381c6fe148..f48f9d0f4e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3625.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3625.json
@@ -1 +1 @@
-{"APIDRA": 4.399460559223785, "ARANESP": 117.31252584383982, "AZATHIOPRINE": 6.794969885066548, "BIKTARVY": 10.926470096349258, "CELLCEPT": 5.149641458745206, "CICLOSPORIN": 17.70164133292436, "CUBICIN": 10.059418181292155, "ELIQUIS": 1.011631236947305, "LANTUS": 2.729196550000333, "OPSUMIT": 4.524268557556765, "PEGINTRON": 1.4854075357112873, "SOLIRIS": 5.917146356762338, "null": 1.087550129238842}
\ No newline at end of file
+{"HUMALOG": 18.37615649644065, "NOVORAPID": 39.74704716142779, "null": 0.5687154937472062}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3626.json
index d4303cccfba..3b3826c0965 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3626.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3626.json
@@ -1 +1 @@
-{"null": 2.720993284414149}
\ No newline at end of file
+{"EMPAGLIFLOZIN": 52.805590231642086, "FORXIGA": 95.06597602674458, "HUMALOG": 8.8618776803873, "JARDIANCE": 35.21378262328731, "KEYTRUDA": 3.270498827914873, "LANTUS": 2.683545717253401, "LEVEMIR": 18.22349013525297, "NOVORAPID": 51.00701204501106, "PEGINTRON": 6.195044171748146, "ZYPREXA": 15.38794202383344, "null": 0.1020207539934939}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3627.json
index 48f89ea98c3..3c654a45d2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3627.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3627.json
@@ -1 +1 @@
-{"ARAVA": 15.3284034178499}
\ No newline at end of file
+{"APIDRA": 34.54442424589089, "COMIRNATY": 0.1676561471563014, "DAPAGLIFLOZIN": 42.34912395885505, "FIASP": 34.554959276089555, "FORXIGA": 7.161253558941774, "GLIBENCLAMIDE": 35.260944383327974, "HUMALOG": 3.3125774080278494, "INSULIN": 51.30736418361257, "JANUMET": 13.37144891497694, "JARDIANCE": 5.250241259986667, "LANTUS": 14.863591503311014, "LEVEMIR": 21.72568252868372, "NOVORAPID": 9.840397894892666, "TOUJEO": 43.04469094927012, "TRULICITY": 5.187875080257822, "VAXZEVRIA": 0.0998560253659616, "null": 0.5835800614448668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3628.json
index 7ad761c8eb5..12533c247e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3628.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3628.json
@@ -1 +1 @@
-{"AMIKACIN": 13.72693929803472, "ANAKINRA": 3.1532712800465563, "ANIDULAFUNGIN": 68.80844849758704, "ARIPIPRAZOLE": 1.956532625467994, "AZACITIDINE": 9.609600102688969, "BRIDION": 7.328419186327952, "BUPIVACAINE": 6.406652284763241, "CELLCEPT": 2.0857970678550046, "CICLOSPORIN": 1.943849656302204, "CLOPIDOGREL": 4.745366518384548, "CYTARABINE": 2.787054549417832, "DEXAMETHASONE": 4.522160790291756, "DEXMEDETOMIDINE": 32.19564129964526, "ENOXAPARIN": 13.966712577101893, "FENTANYL": 10.61494733359656, "GANCICLOVIR": 6.7532442981957965, "GLUCAGON": 25.63312861873641, "IBUPROFEN": 10.237646227088598, "KYMRIAH": 3.1639243104934165, "LEVETIRACETAM": 5.880561818582035, "LEVOFLOXACIN": 4.813153597234976, "MIDAZOLAM": 18.69064788305545, "OLANZAPINE": 2.6228083299362384, "OPSUMIT": 1.832498663470731, "SILDENAFIL": 13.95609906640038, "SUFENTANIL": 18.45473884285001, "TRACLEER": 2.7061258934387142, "null": 2.167595303249528}
\ No newline at end of file
+{"BYETTA": 10.601798627392656, "COMIRNATY": 0.0837972464849476, "HUMALOG": 10.163575927272923, "INSULIN": 8.097540259379958, "JANUMET": 11.181765932664842, "JANUVIA": 8.874988575258415, "LANTUS": 8.231134539903845, "LEVEMIR": 8.541014048919735, "METFORMIN": 28.19550425164873, "MICARDIS": 9.56719642005379, "ZOSTAVAX": 8.178139230090379, "ZYPREXA": 10.300323979748224, "null": 0.9127267600519644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3629.json
index 76d347ed8a1..5535300ffe7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3629.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3629.json
@@ -1 +1 @@
-{"null": 1.4372821117217411}
\ No newline at end of file
+{"APIDRA": 9.021061755633614, "AVONEX": 35.56238215408991, "BYDUREON": 4.991883606997672, "BYETTA": 18.989934859311205, "CICLOSPORIN": 1.5026439991344889, "COMIRNATY": 0.0254994466787531, "CYMBALTA": 1.464176514016603, "ELIQUIS": 1.458949181638711, "EMPAGLIFLOZIN": 8.688665250009107, "FORXIGA": 3.08589345691975, "HUMALOG": 18.282635527128416, "INSULIN": 11.156010529092235, "JANUMET": 19.496526678650312, "JANUVIA": 10.098974786103687, "JARDIANCE": 1.1154675382406287, "LANTUS": 12.524824769019167, "LEVEMIR": 12.642013555297089, "LEVETIRACETAM": 4.293904056210915, "LYRICA": 7.809821889133977, "PEGASYS": 0.4853930718470767, "PLAVIX": 1.4576043737033837, "TRULICITY": 4.413746809934038, "VIAGRA": 2.0076102337676547, "VICTOZA": 3.0292825180028204, "ZOSTAVAX": 12.94488169084056, "ZYPREXA": 19.57954386470773, "null": 0.7067210887724331}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/363.json
index e732ce1f524..c4a7af4fd45 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/363.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/363.json
@@ -1 +1 @@
-{"COMBIVIR": 39.07619223461191, "null": 2.966863723380408}
\ No newline at end of file
+{"ABILIFY": 3.1261983616183264, "AIMOVIG": 1.183335098191629, "ARAVA": 0.2253893835703671, "ARIPIPRAZOLE": 27.388828157449165, "ATRIPLA": 0.222355362901607, "AVAMYS": 5.055907809062501, "BIKTARVY": 8.379935378050146, "BLINDED": 109.6591311425823, "BRIVARACETAM": 15.975556950926018, "BRIVIACT": 48.848659447160486, "BUPRENORPHINE": 3.246687799819938, "CHAMPIX": 9.813886018239751, "COMIRNATY": 0.2166688604700698, "COSENTYX": 1.166068125054273, "CYMBALTA": 2.022134246591913, "DEXAMETHASONE": 1.0122852318923985, "DULOXETINE": 8.700395264656668, "GARDASIL": 0.7505082399009028, "IBRANCE": 0.552893550255481, "KAFTRIO": 13.549843623781474, "KEPPRA": 11.31245086719104, "LATUDA": 5.976906178180464, "LEVETIRACETAM": 7.737605801786861, "LEVOFLOXACIN": 0.8356197536820411, "OLANZAPINE": 4.633152852510166, "PEGASYS": 2.073042001878912, "PEGINTRON": 1.423942878457617, "RIBAVIRIN": 2.300511666048243, "SPIKEVAX": 0.0921053842971867, "SUBOXONE": 2.541486461107473, "TAMIFLU": 1.5572651868822027, "TOZINAMERAN": 0.1572146854643689, "VAXZEVRIA": 0.0463664364121627, "VIMPAT": 3.776545546033588, "XELJANZ": 0.5747013332761675, "XOLAIR": 0.8283498231794431, "ZOSTAVAX": 1.1708832753448823, "ZYPREXA": 0.8569762155969897, "null": 1.5325806485818505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3630.json
index 51a3d619e05..60dbfd4175f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3630.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3630.json
@@ -1 +1 @@
-{"PEGASYS": 20.63941900416405}
\ No newline at end of file
+{"LEVOFLOXACIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3631.json
index 83c31b5bf1b..47c7bf06b18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3631.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3631.json
@@ -1 +1 @@
-{"ADENURIC": 17.513713306348304, "ALISKIREN": 19.86643666036015, "ARANESP": 46.35016574269515, "BEVACIZUMAB": 3.68249565625138, "CELLCEPT": 2.3802088500948595, "CLOPIDOGREL": 4.670267234407192, "CYTARABINE": 21.192435046281325, "ELIQUIS": 2.817907864919251, "IBRANCE": 1.4994309364786125, "JAKAVI": 13.860381055857294, "JARDIANCE": 1.1118061081361448, "KEYTRUDA": 4.1613202131235205, "MEPOLIZUMAB": 4.503253390975902, "NEULASTA": 8.205515259717526, "OLAPARIB": 28.3281796527241, "PEGASYS": 4.651654299375388, "PEGINTRON": 2.26491664928827, "RIBAVIRIN": 5.890354563154924, "RUXOLITINIB": 20.69857129316561, "SOLIRIS": 23.84354479832607, "XOFIGO": 11.868087732710553}
\ No newline at end of file
+{"HUMALOG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3632.json
index 6f733f4d689..1b6e65bddca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3632.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3632.json
@@ -1 +1 @@
-{"ABRAXANE": 1.8912463906037889, "ACE": 6.229015300163077, "ADCIRCA": 1.8448923266996988, "ADEMPAS": 2.208148326650264, "AFINITOR": 2.86928839708625, "ALEMTUZUMAB": 1.0269487723415744, "ALIMTA": 2.6613181790944767, "AMINOSALICYLIC": 2.714781668803715, "ANAGRELIDE": 11.317748609915052, "ANAKINRA": 2.951978272253908, "ANGIOX": 5.936204469293225, "ARANESP": 9.276834811757764, "ARIPIPRAZOLE": 1.0768933733649533, "ARIXTRA": 3.8825875924515976, "ATEZOLIZUMAB": 2.1003973803413603, "AVASTIN": 2.0647602947791115, "AVELUMAB": 1.292234942740545, "AZACITIDINE": 2.012720730019101, "AZARGA": 42.1372592140456, "AZATHIOPRINE": 1.417842350037258, "AZOPT": 25.915378552600057, "BEDAQUILINE": 9.691711705072974, "BELIMUMAB": 1.3697673635826844, "BEVACIZUMAB": 2.438118996756441, "BINOCRIT": 17.484827947962575, "BIVALIRUDIN": 9.590683505364614, "BOCEPREVIR": 3.3490557680806483, "BOSULIF": 2.1044663464687434, "BOSUTINIB": 1.9075045974378977, "BREYANZI": 7.330781152975114, "BRILIQUE": 2.987430651233945, 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1.6230221684212918, "EPIRUBICIN": 5.601204371698806, "EPOETIN": 11.75485243820902, "EPTIFIBATIDE": 7.195146414091758, "ERBITUX": 1.4463570582636045, "ESOMEPRAZOLE": 2.065888897318612, "EVEROLIMUS": 2.107842887709875, "EXJADE": 8.302620842972326, "EXVIERA": 2.635605868865448, "FASLODEX": 2.4165839570644683, "FILGRASTIM": 1.5352661526755302, "FIRDAPSE": 1.1000407228300222, "FOTIVDA": 3.209095355534594, "FULVESTRANT": 2.3343048956768078, "GANCICLOVIR": 1.2101008779900035, "GAVRETO": 5.329737906351069, "GAZYVARO": 1.6034324335681889, "GLIVEC": 2.85573832516597, "GLYCOPYRRONIUM": 5.51214585661806, "HALAVEN": 1.254578082872071, "HARVONI": 1.7252909285763525, "HERCEPTIN": 1.2393884160321391, "HUMAN": 1.432317440873676, "HYCAMTIN": 4.2356837408112336, "HYDROXYCARBAMIDE": 5.15317163087806, "IBRANCE": 3.464622269002616, "ICLUSIG": 1.2298102861358189, "ILARIS": 2.1114073126655204, "IMATINIB": 1.527466067263711, "IMBRUVICA": 1.7565320928906705, "INCIVO": 11.314917350879831, "INLYTA": 1.051804985822827, "INTEGRILIN": 9.765933657006384, "INTERFERON": 3.020494907266305, "INTRONA": 4.814137752741623, "IRINOTECAN": 1.355652961045302, "IRON": 2.18204567252758, "ISCOVER": 3.82535811680806, "JAKAVI": 15.274251938544262, "JEVTANA": 2.455683935165222, "KISQALI": 2.735794503153165, "KYMRIAH": 2.856055594230809, "KYPROLIS": 1.3128686962724907, "LEFLUNOMIDE": 1.1649037939311515, "LEMTRADA": 2.188195330914495, "LIXIANA": 4.208749713484409, "LONSURF": 3.645895770628058, "LUPKYNIS": 1.9001320369518475, "LUTATHERA": 1.9608838475060515, "LYNPARZA": 8.042434918109775, "MABTHERA": 2.2126612255206, "MERCAPTOPURINE": 2.8542490886318124, "METFORMIN": 2.2575391355425576, "METHOTREXATE": 1.8541654258877944, "MIRCERA": 27.150315208530746, "MYCOPHENOLATE": 1.2773261540779604, "NALOXONE": 3.37101379335646, "NEORECORMON": 12.01261877135546, "NEULASTA": 1.3012185775703369, "NINLARO": 2.0406625837343286, "NPLATE": 1.0176974346423908, "OLAPARIB": 5.354272763753961, "OLYSIO": 3.2054666526803826, 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16.205545224929168, "SOVALDI": 8.082692589051026, "SPRYCEL": 1.6194180487003358, "SUTENT": 2.490384422196764, "TASIGNA": 2.3349230606016635, "TAXOTERE": 1.6579275718046844, "TEGAFUR": 6.601374361586855, "TEMODAL": 1.5894553695329936, "THALIDOMIDE": 1.029057542083749, "TICAGRELOR": 6.542218569003436, "TOBRAMYCIN": 1.4793579535899686, "TOPOTECAN": 2.9813532911053526, "TRACLEER": 2.283445841864052, "VELCADE": 2.1962973603249503, "VELTASSA": 1.0851854930259763, "VENCLYXTO": 1.9685178572183133, "VENETOCLAX": 3.189824601126929, "VICTRELIS": 8.251055182924466, "XARELTO": 3.1925131517531797, "XELJANZ": 1.0451966292138783, "XELODA": 1.4070283598636424, "XOFIGO": 13.41192386233636, "XTANDI": 1.391540835552478, "ZEJULA": 5.6470189749710045, "ZEPATIER": 1.4850538047585398, "ZIAGEN": 1.003544950122885, "ZOMETA": 2.360016145650666}
\ No newline at end of file
+{"APIDRA": 74.64642668486613, "EYLEA": 124.91524416884388, "LANTUS": 7.864202723299691, "null": 0.359869774087971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3633.json
index 11746b500c4..3f817544d13 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3633.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3633.json
@@ -1 +1 @@
-{"ARANESP": 15.465779206734448, "CELLCEPT": 2.1956183740138435, "CYMBALTA": 13.606265406869872, "EMPAGLIFLOZIN": 50.79588195266864, "ENTRESTO": 3.014614820253325, "FORXIGA": 6.959852139368632, "JAKAVI": 10.489563991646015, "JANUMET": 2.546846544237235, "JARDIANCE": 12.60911246267694, "KEYTRUDA": 1.522399259957722, "METHOTREXATE": 2.530238492929478, "MIRCERA": 35.968062055525465, "NEXAVAR": 1.4470658222631168, "VOTRIENT": 4.348488230098944, "ZYPREXA": 1.3004748654103646}
\ No newline at end of file
+{"AMINOSALICYLIC": 2.8563304883267358, "APIDRA": 25.62241175860905, "AVANDAMET": 6.479268986983397, "AVANDIA": 5.475881645653248, "BYETTA": 4.392459873595424, "COAPROVEL": 6.390841283081872, "EYLEA": 3.009792118838931, "HUMALOG": 51.53359234562024, "INSULIN": 23.693364850748715, "JANUMET": 2.7914143905797832, "JANUVIA": 7.688628401269162, "JARDIANCE": 1.425292989094144, "LANTUS": 36.31565971121873, "LEVEMIR": 22.54277403965204, "NOVORAPID": 9.191953090472891, "PEGINTRON": 1.20892147622502, "RYBELSUS": 12.8746826756573, "TRESIBA": 17.97207452109052, "TRULICITY": 7.79395430943083, "VIAGRA": 2.106208176336417, "VICTOZA": 7.659902766667088, "ZOSTAVAX": 4.281452551878856, "ZYPREXA": 3.491502538606862, "null": 0.5279217779835498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3634.json
index 75909b65957..57f949c7eee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3634.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3634.json
@@ -1 +1 @@
-{"SPIKEVAX": 17.038389992662317}
\ No newline at end of file
+{"ZOSTAVAX": 30.443431795634822, "null": 0.308562274080619}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3635.json
index e25215479dc..26b792e3afe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3635.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3635.json
@@ -1 +1 @@
-{"ADENURIC": 553.1129733142666}
\ No newline at end of file
+{"NOVORAPID": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3636.json
index 06fd7e72e88..5f32e57cb42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3636.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3636.json
@@ -1 +1 @@
-{"PRIVIGEN": 53.542714015237856, "SOLIRIS": 371.4056217042755}
\ No newline at end of file
+{"null": 2.6528177334228498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3637.json
index 424e8035fff..80082a0af6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3637.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3637.json
@@ -1 +1 @@
-{"ALOXI": 91.04718887035745, "ARANESP": 1.579183383508976, "AZATHIOPRINE": 5.227546476503685, "CELLCEPT": 3.0605721059360813, "CICLOSPORIN": 5.102358584766035, "COMBIVIR": 1.8463751632047836, "CRIXIVAN": 5.218116735602054, "DARZALEX": 2.3652028723529845, "EXJADE": 4.469273073500288, "EXVIERA": 6.469178084977756, "FASTURTEC": 127.16543489514792, "FLEBOGAMMA": 5.9061059658649, "HARVONI": 2.5010698339926307, "HUMAN": 41.31251147247692, "JAKAVI": 4.443354402810808, "KIOVIG": 40.068465592741504, "KYPROLIS": 6.098184267762944, "MYCAMINE": 38.06759928559801, "NPLATE": 2.371862999466807, "PEGASYS": 1.4646571689628998, "PEGINTERFERON": 2.2511420796755077, "PEGINTRON": 2.482441073657569, "PRIVIGEN": 61.155702214235205, "RASBURICASE": 138.26491241134434, "RIBAVIRIN": 15.752057155528544, "ROACTEMRA": 1.048286652394912, "SOLIRIS": 192.81031087555183, "TAMIFLU": 1.055319644289158, "VENETOCLAX": 6.913563576108045}
\ No newline at end of file
+{"ABILIFY": 4.600576611317821, "ARANESP": 59.38906318091595, "ATRIPLA": 0.3577760894572678, "AVANDIA": 1.6954682644995178, "AYESURBY": 963.4787142268171, "CELLCEPT": 1.9481272773724776, "CICLOSPORIN": 4.059769066900705, "COMIRNATY": 0.0198932145556048, "ELIQUIS": 1.1366056749118645, "EXJADE": 6.654257335853846, "HUMALOG": 1.5773981583792358, "JANUMET": 1.7044915943218124, "JANUVIA": 5.127136322397493, "JARDIANCE": 1.0596717222320766, "LANTUS": 9.39108113608843, "LEVEMIR": 12.86628035665496, "MIMPARA": 8.007333561418653, "NOVOSEVEN": 37.984717029716926, "OPSUMIT": 15.949273292126303, "SOLIRIS": 9.081431989782336, "SPIKEVAX": 0.0645643355723988, "SPRYCEL": 2.040094019183029, "TRACLEER": 7.093199902209117, "TRUVADA": 0.6338279203005357, "VELTASSA": 180.3347499129436, "VOTRIENT": 2.6534595252971527, "XTANDI": 0.9582623138127556, "null": 0.8604992643506192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3638.json
index c65b13309d0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3638.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3638.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 2.274984991949653, "ALIMTA": 2.222335508831179, "ATAZANAVIR": 4.045967316400072, "AVASTIN": 2.031984668188326, "BOCEPREVIR": 11.56926518439374, "BUSULFAN": 1.7495016238082255, "CARFILZOMIB": 5.753997062088401, "CELLCEPT": 3.0735853888085813, "CICLOSPORIN": 2.8270629597923365, "COAPROVEL": 2.2740943908133997, "COMBIVIR": 7.7129316927656975, "CRIXIVAN": 12.136848413733292, "EBIXA": 6.088372109860061, "ENTYVIO": 1.071113693675063, "ESOMEPRAZOLE": 2.864394408483126, "EXJADE": 1.9704626654973805, "FASLODEX": 1.2078331716742812, "FASTURTEC": 158.64867509702987, "HARVONI": 1.7527049071074634, "HUMAN": 34.38749880849628, "INCIVO": 2.962167094576873, "INTERFERON": 11.715555197298055, "INTRONA": 18.447631254296628, "IPILIMUMAB": 1.3119796003081556, "ISENTRESS": 2.8637396476965136, "JAKAVI": 1.3434576578982418, "KEYTRUDA": 1.3610689301670873, "KIOVIG": 15.936833509753832, "KYPROLIS": 9.987702033127498, "LEMTRADA": 5.458240986614634, "LEVOFLOXACIN": 1.4305531519195456, "MIDAZOLAM": 1.298570024823416, "MYCAMINE": 18.52614058850419, "MYCOPHENOLATE": 2.3839014661997275, "NORVIR": 2.356238692080797, "NOT": 2.4442927886467456, "NOVONORM": 9.242107666145804, "NPLATE": 3.15142464965738, "OPDIVO": 1.1489801652735945, "PEGASYS": 8.697255856136703, "PEGINTERFERON": 7.266141775465452, "PEGINTRON": 7.391910526407071, "PLAVIX": 1.1094298234383138, "PRIVIGEN": 31.21080953731264, "RASBURICASE": 154.15323944948963, "REBETOL": 32.980256969230524, "RIBAVIRIN": 16.574781536664425, "SOLIRIS": 5.002499370960031, "SOVALDI": 12.313385417004216, "TAMIFLU": 1.561077195153156, "TEMODAL": 3.4656108183205223, "VENETOCLAX": 3.1415786739025995, "null": 1.6843255887061008}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3639.json
index 32ca5dda61c..c1c8906f1ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3639.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3639.json
@@ -1 +1 @@
-{"null": 1.170753833896769}
\ No newline at end of file
+{"null": 0.809811682955197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/364.json
index 42e0f4ef64c..517ac389d75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/364.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/364.json
@@ -1 +1 @@
-{"ATOSIBAN": 364.09945230536647, "BUPRENORPHINE": 19.956743561398472, "COMBIVIR": 53.43388190337051, "TRACTOCILE": 1509.8887549805152, "null": 1.492510749497746}
\ No newline at end of file
+{"COMIRNATY": 0.2097129355166405, "ELIQUIS": 3.00796519342737, "EYLEA": 97.08277617972388, "FORSTEO": 6.422883223678346, "LANTUS": 3.054767582525908, "ZOSTAVAX": 5.637977811393763, "null": 1.4531158488318772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3640.json
index 226d74e015f..17a3ff926ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3640.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3640.json
@@ -1 +1 @@
-{"AVASTIN": 4.578669634867675, "CARFILZOMIB": 21.999287860977063, "CELLCEPT": 11.023874493575608, "CICLOSPORIN": 28.36188133278254, "CLOPIDOGREL": 1.5262739136805838, "KYPROLIS": 31.87407445538449, "RAPAMUNE": 82.5573018803982, "SOLIRIS": 58.054788372196384, "SUTENT": 1.1401304731651252, "null": 1.4303587697044615}
\ No newline at end of file
+{"null": 0.5983845148152901}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3641.json
index 1de8ddb8d9d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3641.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3641.json
@@ -1 +1 @@
-{"BRILIQUE": 9.207245743825474, "CETROTIDE": 166.83489865666, "CLOPIDOGREL": 4.929171367544738, "ELIQUIS": 6.185539797605499, "ENOXAPARIN": 29.423537489277283, "GONALF": 75.7209910932926, "NEXAVAR": 2.38478140710606, "NOVOSEVEN": 31.41375430989804, "PLAVIX": 6.824813963704834, "SILDENAFIL": 11.033157092236992, "SUTENT": 1.1072730197167766, "null": 2.4788470182341094}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3642.json
index c3ab89fab23..bd552fc4a5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3642.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3642.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 18.731535804325123, "ANAKINRA": 17.560226980134424, "ASPARAGINASE": 1.9147054006094204, "AZACITIDINE": 14.078457478158864, "AZATHIOPRINE": 5.350029710164987, "BORTEZOMIB": 3.8214682307629415, "BUSULFAN": 12.735978819569176, "CABOMETYX": 2.0357375667300777, "CANCIDAS": 5.224009958049547, "CASPOFUNGIN": 7.296665380041955, "CELLCEPT": 6.778601802457466, "CICLOSPORIN": 16.227763247282358, "CYTARABINE": 9.633523333615232, "DABRAFENIB": 14.5978623926523, "DEXAMETHASONE": 6.631100710643286, "DOXORUBICIN": 3.5056478274243608, "EPIVIR": 5.60846677252474, "FILGRASTIM": 12.59214449028324, "GANCICLOVIR": 19.533609795889223, "INCIVO": 1.913153524657706, "INFLIXIMAB": 7.166093809176325, "IPILIMUMAB": 11.841191342117146, "JAKAVI": 1.2835854656442278, "KEPPRA": 1.2138680061283176, "KEYTRUDA": 8.293491465441878, "KYMRIAH": 39.15127894587606, "LEMTRADA": 2.4605507148224097, "LEVETIRACETAM": 3.036925348731608, "LEVOFLOXACIN": 1.971796690788064, "MEKINIST": 10.831384908967244, "MELPHALAN": 22.19933142471585, "MERCAPTOPURINE": 15.926663805086678, "METHOTREXATE": 3.399820832663249, "MYCOPHENOLATE": 7.553402835945369, "OPDIVO": 16.57668238767877, "PEMBROLIZUMAB": 5.397512314161308, "RITUXIMAB": 1.635882193487951, "ROACTEMRA": 5.819406856156153, "ROTATEQ": 2.430479498462464, "SOLIRIS": 1.7877328882403762, "TISAGENLECLEUCEL": 61.20934212873309, "TOCILIZUMAB": 25.374087184507168, "YESCARTA": 29.78905983703002}
\ No newline at end of file
+{"null": 0.6579458467610275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3643.json
index 11c8a3d3464..7f7b7578756 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3643.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3643.json
@@ -1 +1 @@
-{"NUCALA": 25.818799675999053}
\ No newline at end of file
+{"COMIRNATY": 2.2250160954174683, "SPIKEVAX": 2.1135581806443864, "TOZINAMERAN": 1.631766236142301, "VAXZEVRIA": 1.408935319991692, "null": 0.3683033014101025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3644.json
index 9b481ea06ef..6314a152127 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3644.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3644.json
@@ -1 +1 @@
-{"ACLIDINIUM": 2.286225686888364, "ACTOS": 2.2807410413479507, "ADCIRCA": 6.78110142447869, "ADEMPAS": 3.2755053627031425, "AFINITOR": 1.3385075103145685, "ALEMTUZUMAB": 1.4874410725971103, "ALIMTA": 4.193107464974718, "AMBRISENTAN": 3.306428790812638, "AMIKACIN": 2.5768331030786094, "AMINOSALICYLIC": 2.647837925592657, "ANORO": 38.18157543367143, "APIXABAN": 6.17746490803406, "AVAMYS": 2.089323539632589, "AVASTIN": 2.7342387105537305, "AZATHIOPRINE": 5.4080638296531145, "AZTREONAM": 6.239221114461407, "BEDAQUILINE": 4.7528885389955535, "BEVACIZUMAB": 2.456775051238413, "BOSENTAN": 6.540342458308255, "BRIDION": 1.2572297134347723, "BRILIQUE": 9.466953595859737, "BUDESONIDE": 4.195273060025049, "CABOMETYX": 1.922721746326124, "CANCIDAS": 2.0902331337684217, "CASPOFUNGIN": 3.125288015284393, "CLOPIDOGREL": 8.334232792604215, "COLOBREATHE": 26.677273143342997, "DELAMANID": 3.0335211794686545, "DEXAMETHASONE": 1.1211899930746836, "EFIENT": 6.7696065688410485, "ELIQUIS": 6.262239185797077, "ENOXAPARIN": 9.995659833612605, "ENVARSUS": 26.029058926580912, "ESBRIET": 3.423276868722763, "EVEROLIMUS": 2.70950515316095, "FASENRA": 1.334589139931819, "FILGRASTIM": 2.3648124959167345, "FLUTICASONE": 16.221649773276933, "INLYTA": 2.5164452478470167, "INTEGRILIN": 14.394136447758727, "IRESSA": 4.967856209861063, "ISCOVER": 6.329459482389591, "KAFTRIO": 8.355507874314938, "KALYDECO": 18.93344787110714, "KEYTRUDA": 1.6408138605892382, "LAMIRA": 29.319983795503493, "LEMTRADA": 2.8027649736590625, "LENVIMA": 4.824375820268939, "LEVOFLOXACIN": 1.3616998818421624, "LIXIANA": 4.789159600438884, "MABTHERA": 1.2282054576580792, "MELATONIN": 1.3174755310698936, "NEXAVAR": 5.931159267589055, "NUCALA": 4.947750098599382, "OFEV": 3.524722204336436, "OPSUMIT": 3.142504543574226, "ORKAMBI": 13.127019942616585, "PAZOPANIB": 2.8429838048179588, "PEGASYS": 1.722378137080847, "PEGINTERFERON": 1.415529179213846, "PEGINTRON": 1.2443217950060628, "PEMBROLIZUMAB": 1.1385065433774726, "PEMETREXED": 4.260469760728439, "PLAVIX": 8.711071841550929, "PRADAXA": 5.857052232169145, "RELVAR": 1.570519458531762, "REVATIO": 2.371609943397331, "RIVAROXABAN": 6.144725613183323, "SILDENAFIL": 3.241616977688742, "SUTENT": 3.3301557083350573, "TAGRISSO": 2.417693027600344, "TICAGRELOR": 11.78474493545197, "TOBI": 72.22021283293803, "TOBRAMYCIN": 2.673796057072801, "TORISEL": 2.4054583742737488, "TRACLEER": 5.124650840363503, "TRELEGY": 2.563683852407619, "VFEND": 4.06263832952699, "VORICONAZOLE": 3.313785930625285, "VOTRIENT": 3.8723978105776578, "XALKORI": 2.580986328000739, "XARELTO": 11.070736938417404, "null": 1.0313140368687652}
\ No newline at end of file
+{"COMIRNATY": 0.2511305547593296, "METHOTREXATE": 11.396525231583048, "null": 1.2628807928853012}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3645.json
index 68e2f8d30f1..104af3bec79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3645.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3645.json
@@ -1 +1 @@
-{"ADEMPAS": 1.093176724742373, "ADVATE": 48.52981161493238, "AMBRISENTAN": 1.251556151344426, "ANGIOX": 9.510545799059694, "ARIXTRA": 6.716240857934408, "AVASTIN": 1.5972666099423332, "AVELUMAB": 1.499334993629302, "AYESURBY": 62.75145750431325, "BEVACIZUMAB": 1.4810499972450597, "BRILIQUE": 7.224607059288683, "BRUKINSA": 3.0681788348271937, "CLOPIDOGREL": 6.083684213450085, "DALIRESP": 2.949708418686076, "DEFITELIO": 8.510115711550345, "EFIENT": 16.5862414762846, "ELIQUIS": 17.798524805912308, "ELOCTA": 19.04951723366358, "EMICIZUMAB": 14.55526280144404, "ENFUVIRTIDE": 5.8560969226171045, "ENOXAPARIN": 12.352592852079948, "ENTYVIO": 1.159959559646475, "ENZALUTAMIDE": 1.0044772368890331, "EPTACOG": 35.604339240848724, "ESMYA": 2.41273149424914, "EVRA": 2.6639405214270164, "FILGRASTIM": 1.9773723442195257, "FONDAPARINUX": 13.988939581079691, "HEMLIBRA": 77.88142669776944, "IBRANCE": 1.2724852261958206, "IBRUTINIB": 4.512287200584412, "IMBRUVICA": 3.362983453119168, "IMIQUIMOD": 2.700703525230742, "INHIXA": 3.5419532050873657, "INLYTA": 1.7079996684324583, "INTEGRILIN": 21.033080146512084, "ISCOVER": 7.595728311471835, "JAKAVI": 2.421802344151949, "JIVI": 67.11805663276392, "KOGENATE": 41.95756806455338, "KOVALTRY": 103.14428869768828, "LENVIMA": 1.2404599361568966, "LIXIANA": 7.066698727829784, "METHOTREXATE": 1.1336874121322775, "NEXAVAR": 1.0174243387876487, "NEXOBRID": 13.373231443085857, "NOVOSEVEN": 17.61263571739453, "NPLATE": 5.925795297407532, "NUCALA": 1.3318154332998264, "OPSUMIT": 1.017640130022141, "PLAVIX": 15.74756841204318, "PRADAXA": 7.992522673816503, "PRAXBIND": 22.571761085566408, "REVATIO": 1.945589908825364, "RIVAROXABAN": 3.931876757998063, "RUXOLITINIB": 1.423679465802629, "SILDENAFIL": 1.0075743491347813, "SOLIRIS": 1.1994859777079834, "SPRYCEL": 2.173939979543705, "STELARA": 1.363420459631507, "SUTENT": 2.884135612966572, "TICAGRELOR": 3.423993774908652, "TOZINAMERAN": 1.772535810786986, "VOTRIENT": 1.406308978588635, "XARELTO": 8.218444847100072, "XELJANZ": 1.605413168873415, "null": 1.3181284507641644}
\ No newline at end of file
+{"null": 1.7381354957308035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3646.json
index 738cc2e5634..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3646.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3646.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 606.3711542686203}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3647.json
index 7e41dee55e7..5f97310265c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3647.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3647.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 82.92966050686984, "null": 1.874672078193524}
\ No newline at end of file
+{"TRELEGY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3648.json
index fcefec17e0d..31eb63ca6a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3648.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3648.json
@@ -1 +1 @@
-{"ADVATE": 9.704736643486026, "ALEMTUZUMAB": 1.0725571287659097, "ANGIOX": 30.169453963045854, "APIXABAN": 2.0143098112869464, "ASPARAGINASE": 2.268977166156065, "BRILIQUE": 19.74181988470945, "BUSULFAN": 2.719897178621857, "CAELYX": 2.6532110974691308, "CICLOSPORIN": 2.1011426325548053, "CLOPIDOGREL": 13.289600581470593, "CRIXIVAN": 2.776626296418392, "CUBICIN": 1.742027073103282, "CYTARABINE": 1.0247824452311884, "EFIENT": 17.58699624761932, "ELIQUIS": 32.474074870565154, "ENOXAPARIN": 11.218470201155275, "EPTIFIBATIDE": 73.12327039440846, "EXJADE": 1.4868307345377263, "HEMLIBRA": 6.886895254851355, "HUMAN": 1.7434966058622254, "HYDROCORTISONE": 1.538528522266671, "INTEGRILIN": 99.62991781874044, "ISCOVER": 9.673882097408493, "KALETRA": 1.2161123799747966, "LIXIANA": 5.92703356924056, "NOVOSEVEN": 18.8527181572159, "NPLATE": 6.177479515365452, "PLAVIX": 13.366081867265708, "PRADAXA": 12.297014285110066, "PRASUGREL": 24.23070147526959, "PRAXBIND": 66.54078888492823, "RETEPLASE": 141.09699798553353, "SPRYCEL": 1.3502557272852551, "TEMODAL": 2.6311387453592663, "TICAGRELOR": 12.488215838481278, "XARELTO": 10.166937592885102, "null": 1.494047732182291}
\ No newline at end of file
+{"COMIRNATY": 0.253576332034624, "null": 2.0197843529411643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3649.json
index 6da6e667bec..db318d20cd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3649.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3649.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"null": 1.3199170279832728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/365.json
index 8946472cee3..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/365.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/365.json
@@ -1 +1 @@
-{"ARAVA": 3.9938957372538497, "ATRIPLA": 2.719320791645615, "BYETTA": 23.2573218001352, "JANUMET": 20.214009215199265, "JANUVIA": 39.20223787633837, "TRUVADA": 4.215352552502857, "ZOSTAVAX": 5.041247281409118}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3650.json
index 2e054cec6c5..b56ab9979dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3650.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3650.json
@@ -1 +1 @@
-{"ADVATE": 9.736029390613254, "AVASTIN": 1.4653787944542631, "BRILIQUE": 2.916010513658188, "BRUKINSA": 42.19485753973184, "CLOPIDOGREL": 29.29084204706705, "EFIENT": 17.394324507521002, "ELIQUIS": 27.84313481040556, "ENOXAPARIN": 44.10508653729318, "JAKAVI": 2.1028278670910727, "LIXIANA": 9.625573609595731, "MACITENTAN": 19.83906753344544, "NEXAVAR": 1.0561860521666375, "PLAVIX": 31.575018865403024, "STIVARGA": 1.3680755042568875, "SUTENT": 1.2092165217456927, "TAMIFLU": 1.3598692567135402, "TICAGRELOR": 28.148778203318603, "VFEND": 1.184483256549934, "VOTRIENT": 1.734915605355236, "XARELTO": 5.863796995998415}
\ No newline at end of file
+{"COMIRNATY": 0.8157323865466871, "null": 1.0172532373180796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3651.json
index 22514f5ccc8..d77163ff964 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3651.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3651.json
@@ -1 +1 @@
-{"null": 1.070559733320756}
\ No newline at end of file
+{"ABACAVIR": 0.3624798958408038, "ABASAGLAR": 0.5684957400663552, "ABATACEPT": 1.1838086224083624, "ABEMACICLIB": 3.853936042933469, "ABILIFY": 0.2971552493041241, "ABRAXANE": 1.403567727564934, "ACCOFIL": 1.40053442658092, "ACLASTA": 1.119279546293927, "ACTOS": 0.5402548677907183, "ACTRAPID": 0.3871272851868768, "ADALIMUMAB": 1.0309765381265343, "ADCETRIS": 0.9995704441336, "ADCIRCA": 1.9118158854932497, "ADEMPAS": 2.355901929805038, "ADENURIC": 2.183441224464569, "ADVAGRAF": 2.289830061107125, "AERIUS": 1.1116470705655082, "AFATINIB": 4.689944611168707, "AFINITOR": 1.8146140518979688, "AFLIBERCEPT": 5.481155724762733, "AGOMELATINE": 0.8199500417588779, "AIMOVIG": 0.7564784901894719, "ALDARA": 0.693875277586296, "ALEMTUZUMAB": 0.5484160308007365, "ALIMTA": 1.6156291557401157, "ALISKIREN": 0.092389467429315, "ALL": 0.447875934844954, "ALOGLIPTIN": 1.397092293669471, "ALOXI": 0.8186138720849125, "ALPELISIB": 3.353386602840578, "AMBRISENTAN": 1.4419868863706389, "AMGEVITA": 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1.2524091081498552, "VOTRIENT": 3.738750469808292, "XALKORI": 1.944328844988365, "XARELTO": 0.6089176407342739, "XELJANZ": 1.1551062241756034, "XELODA": 5.185880408195997, "XERMELO": 8.022824619619023, "XGEVA": 0.8317642418181955, "XOFIGO": 1.6099326660893292, "XOLAIR": 0.4244052934014368, "XTANDI": 1.3326038524629136, "XYREM": 0.48373763144191, "YERVOY": 5.713554974343367, "YESCARTA": 0.3702202034219726, "YONDELIS": 0.4181750202581092, "ZALTRAP": 7.946907906353174, "ZARZIO": 1.1182867815481374, "ZAVESCA": 4.7741977699930365, "ZEJULA": 0.8995317392930328, "ZELBORAF": 1.6430744851013943, "ZEPATIER": 1.3627767849561143, "ZEVALIN": 0.9320660799629944, "ZIAGEN": 1.8782847223872663, "ZINBRYTA": 0.6280510004119073, "ZOMARIST": 2.788184242509109, "ZOMETA": 0.4833235449095702, "ZOSTAVAX": 0.3049850405029944, "ZYCLARA": 0.991720335709368, "ZYDELIG": 4.664362395774028, "ZYLLT": 1.6318735323764555, "ZYPADHERA": 0.0579515200786318, "ZYPREXA": 0.219638400598537, "null": 1.0194679547686143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3652.json
index 645c6599072..fce0840075f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3652.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3652.json
@@ -1 +1 @@
-{"BRILIQUE": 10.087832117561074, "CLOPIDOGREL": 15.200713485472326, "ELIQUIS": 14.868732934547223, "ENOXAPARIN": 9.713266419414415, "INLYTA": 4.709692375194555, "JARDIANCE": 1.6017496343244857, "JEVTANA": 10.794935028984996, "LEVOFLOXACIN": 2.1935999456022794, "LIXIANA": 7.682373977381654, "PLAVIX": 12.316908246133815, "STIVARGA": 3.711476793133804, "SUTENT": 4.063117811264993, "TICAGRELOR": 13.819169447400435, "TOZINAMERAN": 1.570479830772599, "VIAGRA": 4.050255366374707, "VOTRIENT": 4.222287702930135, "XARELTO": 7.389123279562001, "XTANDI": 7.8092025705464865}
\ No newline at end of file
+{"ADALIMUMAB": 0.6174048245220363, "ALEMTUZUMAB": 2.917869784957213, "AMINOSALICYLIC": 3.1154892761955524, "ARAVA": 0.1775787533158334, "AUBAGIO": 1.3416915837032786, "BRAFTOVI": 2.236318881032428, "BRILIQUE": 1.9908539879799236, "BRINTELLIX": 0.9685831880257296, "BUDESONIDE": 1.1707707842216593, "BUSULFAN": 2.071195005748326, "CELLCEPT": 1.264628830857358, "CHAMPIX": 1.187352434436928, "CICLOSPORIN": 2.7498896170028164, "CIMZIA": 0.9235807313806312, "CLOPIDOGREL": 3.8557551850391056, "COMIRNATY": 0.3203094329985198, "COSENTYX": 4.5647714075403885, "CYMBALTA": 0.2465847103402796, "ELIQUIS": 1.4775686710601796, "ENBREL": 0.7509703460778527, "ENTYVIO": 17.842203377836753, "EXJADE": 1.1331385081472107, "FORSTEO": 0.6062773999649719, "HUMIRA": 5.491319198468094, "INFLIXIMAB": 4.994576768371735, "IPILIMUMAB": 2.286442173828978, "KEYTRUDA": 0.6989013848700848, "LEVOFLOXACIN": 0.6108108762666529, "MERCAPTOPURINE": 9.594908011361444, "NEXAVAR": 0.696851268726137, "OFEV": 2.884805684208494, "OLANZAPINE": 0.6619215716920533, "PEGASYS": 1.4036324814870276, "PLAVIX": 1.7102608034957436, "ROTATEQ": 29.65236647421152, "SAXENDA": 3.903181212810469, "SIMPONI": 3.979523135283906, "SOLIRIS": 1.7010534701776134, "SPIKEVAX": 0.2900271754811503, "SPRYCEL": 1.6792606685858391, "STELARA": 2.287763448273924, "SUTENT": 1.4695053235005209, "TAMIFLU": 3.9338235951842746, "TICAGRELOR": 10.417887976840806, "TOZINAMERAN": 0.587205254523817, "TWINRIX": 2.595402375200736, "VAXZEVRIA": 0.2093215525757345, "VEDOLIZUMAB": 26.865440061831706, "VOTRIENT": 1.7218166145108704, "XARELTO": 2.3036907577629604, "XELJANZ": 2.7409318352565357, "YERVOY": 7.462390705172848, "null": 1.4795671882408057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3653.json
index 86576850e3d..78eef91826b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3653.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3653.json
@@ -1 +1 @@
-{"PLAVIX": 159.1499442552488, "XARELTO": 245.64703109920376}
\ No newline at end of file
+{"ALEMTUZUMAB": 32.44358979549113, "null": 1.3410851809386155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3654.json
index 38d5a2317f3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3654.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3654.json
@@ -1 +1 @@
-{"null": 1.550275335595429}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3655.json
index e792272c200..11f31ea0ebb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3655.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3655.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 22.076405145247605, "ELIQUIS": 27.942138335375837, "PEGINTRON": 6.815147075760715, "PLAVIX": 9.178141916272528}
\ No newline at end of file
+{"null": 0.8204645188478649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3656.json
index 802054487da..b03e9411a24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3656.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3656.json
@@ -1 +1 @@
-{"AIMOVIG": 1.2191841543145738, "ARAVA": 4.07947572293086, "BRILIQUE": 8.426369520727583, "BUDESONIDE": 1.2224790655048774, "CLOPIDOGREL": 6.633822737918919, "COSENTYX": 2.782832673692019, "ELIQUIS": 10.86553708568885, "EMTRICITABINE": 14.743719408191971, "HUMIRA": 1.7502249206881837, "JAKAVI": 2.2439453542282384, "LIXIANA": 6.808872444652647, "MMRVAXPRO": 1.2806835772783034, "NPLATE": 6.169661660172122, "PEGASYS": 1.4917649316922474, "PEGINTRON": 1.156054831804991, "PLAVIX": 11.20542355451585, "ROACTEMRA": 2.237922972050047, "SUTENT": 2.2546171686700407, "VFEND": 2.1958086240305077, "XARELTO": 8.985751905708424, "null": 1.132249413797071}
\ No newline at end of file
+{"ALENDRONATE": 427.6668497195958, "APIXABAN": 36.35757128796581, "ARIPIPRAZOLE": 13.659825446169648, "AVANDIA": 10.627815105201469, "BRILIQUE": 5.560850785256481, "BUDESONIDE": 3.9041260141552767, "CLOPIDOGREL": 2.89392952693945, "COMIRNATY": 0.1604638080750335, "DEXAMETHASONE": 2.588943072809048, "ELIQUIS": 2.8695711370276795, "ENTRESTO": 14.840339271146098, "FENTANYL": 3.885728280287566, "IBUPROFEN": 4.438616625349551, "JANUVIA": 3.791467854441077, "KYPROLIS": 16.898640232751088, "OPSUMIT": 2.066705991246776, "SPIKEVAX": 0.1202648198041512, "SUTENT": 0.749196735334796, "TASIGNA": 4.367754092996629, "ZOSTAVAX": 4.6518742970069935, "null": 0.8288319734718032}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3657.json
index f0ea5c71854..51c0e41b80e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3657.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3657.json
@@ -1 +1 @@
-{"METHOTREXATE": 146.23141070904936, "null": 1.4952445862083286}
\ No newline at end of file
+{"COMIRNATY": 0.5361488511551555, "VAXZEVRIA": 0.7142002317762841, "null": 1.7003486630193925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3658.json
index 78c5f692fb5..dceda1663a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3658.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3658.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 2.9681909075899995, "ELIQUIS": 13.454808682038507, "SUTENT": 1.5377869430377809, "TOZINAMERAN": 1.6195966631416732, "null": 2.04733162588644}
\ No newline at end of file
+{"KEPPRA": 22.436696982720417, "null": 1.8488352042833816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3659.json
index dd2b9e4fedd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3659.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3659.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 19.70840956180619, "PLAVIX": 17.458051117642274}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/366.json
index c5a91926523..0c114623f32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/366.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/366.json
@@ -1 +1 @@
-{"SUBOXONE": 94.80725815708314}
\ No newline at end of file
+{"AERIUS": 1.6513268117871838, "AFINITOR": 0.562874057613253, "AIMOVIG": 0.3534180832700633, "APROVEL": 2.181154585719559, "ARAVA": 0.0447551212878061, "AUBAGIO": 0.4219640395795465, "AVAMYS": 1.4301373957707009, "BENLYSTA": 0.7257172023613776, "BOSULIF": 0.8284431081196145, "BRILIQUE": 0.5998132125983044, "BRINTELLIX": 0.5178626111095369, "BYDUREON": 0.6458287556585097, "CABOMETYX": 2.0209829234739463, "CHAMPIX": 1.8191706564569137, "CIMZIA": 0.1061060091491466, "CLOPIDOGREL": 0.5026457582839499, "COMIRNATY": 1.479727549019835, "COSENTYX": 0.4184566627585396, "CYMBALTA": 0.2825901028674728, "ELIQUIS": 0.2744582860525618, "ENTRESTO": 0.1820598586060348, "ESBRIET": 1.7907540631639374, "EXFORGE": 0.5100428466520227, "FASENRA": 0.7413560188340019, "FIRDAPSE": 1.634589094495586, "FORSTEO": 0.2542664240308497, "FORXIGA": 0.3430089643595947, "HUMIRA": 0.8894462493648372, "HYDROCORTISONE": 0.664280691807754, "IBRANCE": 1.393949609394696, "INCIVO": 0.9696292388145724, "INLYTA": 1.0146623761027234, "JARDIANCE": 0.4365600998054824, "KALETRA": 0.3841069169323503, "KEPPRA": 0.3215525337617919, "KEYTRUDA": 0.4072815420426079, "LANTUS": 0.0969911395552545, "LATUDA": 1.3927870182214923, "LEVOFLOXACIN": 0.1881687929889188, "LONSURF": 0.9518315074263916, "MICARDIS": 0.5238163060624129, "MODERNA": 0.7267159507189577, "MULTAQ": 0.7426976214911801, "NUCALA": 0.2202674940677975, "OCRELIZUMAB": 1.63791528377841, "OFEV": 1.6795318284776075, "PEGASYS": 0.4845181480826839, "PEGINTERFERON": 0.4100520215527025, "PEGINTRON": 0.9461641905047098, "PLAVIX": 0.514807387791587, "RELVAR": 2.821985525302036, "SHINGRIX": 0.2497731918092217, "SIMPONI": 0.2593820254759423, "SPIKEVAX": 1.2027072038243412, "STELARA": 0.6549961853725851, "SUBOXONE": 0.3943406822078345, "SUTENT": 7.004153537337828, "TAGRISSO": 0.5431882057943778, "TAMIFLU": 0.8345196786763602, "TOVIAZ": 0.558912275547017, "TOZINAMERAN": 2.0444294047324627, "TRELEGY": 0.4719670895386652, "TRULICITY": 0.5629652403286064, "VAXZEVRIA": 1.7185521232215402, "VOTRIENT": 2.773918290459512, "XALKORI": 1.4281870748672738, "XELJANZ": 0.2698740253814119, "XTANDI": 1.9476693521641344, "ZELBORAF": 1.7395733987266109, "ZOSTAVAX": 0.2690324779959924, "null": 1.20100904002958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3660.json
index e887d1b74eb..a7098b4223c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3660.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3660.json
@@ -1 +1 @@
-{"ELIQUIS": 42.25727010196169}
\ No newline at end of file
+{"KEPPRA": 173.14810907489195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3661.json
index 7cdf3663e80..bd57eb50589 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3661.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3661.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 22.542772065178504, "ELIQUIS": 23.964531344603422, "VAXZEVRIA": 1.0049876711964705}
\ No newline at end of file
+{"LANTUS": 18.55163812371005, "null": 0.4844916277673874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3662.json
index 214c8dde68e..e13780f2a3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3662.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3662.json
@@ -1 +1 @@
-{"GARDASIL": 8.90084121236159, "null": 1.08705374337669}
\ No newline at end of file
+{"ARIPIPRAZOLE": 12.589545519146707, "COMIRNATY": 0.1261599350393455, "JARDIANCE": 5.386405571457816, "ROTATEQ": 82.95499891934783, "ZYPREXA": 5.387113282423931, "null": 1.3415216646432084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3663.json
index 645e3bfe25a..109b20c87d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3663.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3663.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.5621524673133047, "APIXABAN": 1.10893938050532, "ARIXTRA": 12.967585947209905, "AVANDIA": 1.8130266390310807, "BRILIQUE": 18.01485207365553, "BRINTELLIX": 1.2079795792748684, "BUPRENORPHINE": 1.212417220578261, "CLOPIDOGREL": 5.261956464789226, "EFIENT": 11.387880975385707, "ELIQUIS": 23.605829252793217, "ENOXAPARIN": 6.035949159890146, "EVENITY": 3.578442986039483, "EVISTA": 4.585353696442629, "EYLEA": 2.5175891256387826, "HARVONI": 3.049237843951357, "INTEGRILIN": 13.3021975125005, "LIXIANA": 6.301820941326927, "MEKINIST": 1.7378757463594745, "PLAVIX": 29.191157039294648, "PRADAXA": 15.779312018217611, "ROACTEMRA": 1.163139732849112, "SOLIRIS": 1.1280249850444926, "SUTENT": 1.384120049731119, "VOTRIENT": 1.5301820279830731, "XARELTO": 23.98177836364397, "ZOSTAVAX": 1.230837595085694}
\ No newline at end of file
+{"ELIQUIS": 10.914739390190544, "PLAVIX": 28.773650699679507, "null": 1.1178290214646136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3664.json
index 3a7e1d17754..f7eaca62d03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3664.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3664.json
@@ -1 +1 @@
-{"BRILIQUE": 19.48463768094077, "CLOPIDOGREL": 21.22556176377692, "ELIQUIS": 16.532783812562613, "PLAVIX": 21.71508144073877, "PRAXBIND": 384.43779001517566, "XARELTO": 31.698128636877968}
\ No newline at end of file
+{"SPIKEVAX": 28.18024942030929}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3665.json
index f537c6a9090..5934d09cbed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3665.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3665.json
@@ -1 +1 @@
-{"null": 1.2476389963413008}
\ No newline at end of file
+{"null": 1.990131881848063}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3666.json
index 91802e8b784..f8a86ff01f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3666.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3666.json
@@ -1 +1 @@
-{"JANUVIA": 55.17256324537502}
\ No newline at end of file
+{"CYTARABINE": 38.50325125929505, "DEXAMETHASONE": 12.326770421750057, "TRISENOX": 6457.682812330478, "null": 0.3704631383336857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3667.json
index d94eaf10285..da37190d630 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3667.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3667.json
@@ -1 +1 @@
-{"AFINITOR": 1.6468028217821404, "BRILIQUE": 8.059538896035678, "CELLCEPT": 2.311765813871215, "CLOPIDOGREL": 6.314302532514554, "DEXAMETHASONE": 2.0084453982898096, "ELIQUIS": 20.2293577897148, "INCIVO": 17.434684076443634, "LIXIANA": 12.95557426756336, "NEXAVAR": 1.8558935856650896, "PEGASYS": 2.493162542268886, "PEGINTERFERON": 7.772747236671253, "PEGINTRON": 2.5254171607097837, "PLAVIX": 12.933937152801573, "SUTENT": 6.045567618161792, "TICAGRELOR": 10.6583566207891, "VOTRIENT": 3.0485178520053084, "XARELTO": 45.96255273256549}
\ No newline at end of file
+{"ADALIMUMAB": 1.2253963176789116, "ARANESP": 4.595192075704749, "AUBAGIO": 4.692491290429671, "BIKTARVY": 14.41012687130484, "COMIRNATY": 1.2617446180228953, "CYMBALTA": 1.2392918391935326, "ELIQUIS": 1.7357894863787786, "METHOTREXATE": 4.363914781679276, "SPIKEVAX": 0.4200975282574581, "VAXZEVRIA": 0.1587692721283484, "XOLAIR": 2.6869496960160277, "null": 0.967869921640434}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3668.json
index dd8f3e5072a..5fe022e66ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3668.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3668.json
@@ -1 +1 @@
-{"AVONEX": 8.808383760899382, "BRAFTOVI": 1.1281360019816011, "BRILIQUE": 2.138532505839746, "BYETTA": 1.4172139175846998, "COMBIVIR": 1.5490095373978567, "ELIQUIS": 2.844159977369024, "ENTYVIO": 3.037647562333887, "EPADERM": 104.38002836808998, "FASLODEX": 1.0108577711797453, "FENTANYL": 1.2026527649178176, "FIRDAPSE": 2.041104762101816, "FORSTEO": 4.518052595958407, "HUMIRA": 1.9508007051578105, "HYDROCORTISONE": 1.949797066125647, "ICLUSIG": 1.2694460083969372, "INCIVO": 20.332976185088366, "INLYTA": 1.2063272923882933, "ISENTRESS": 3.199122225151042, "JANUMET": 3.0484671735528712, "JANUVIA": 2.105559600716193, "LIXIANA": 1.7342555483183104, "OFEV": 1.0105478027203003, "OPTIMARK": 1.030815123248067, "PEGASYS": 4.931697417775261, "PEGINTERFERON": 9.805466173611904, "PEGINTRON": 1.872622170084986, "PLAVIX": 1.4776354066299946, "RIBAVIRIN": 1.7898138491652325, "SAXENDA": 1.329415699695197, "SPRYCEL": 1.219159628661041, "STEROIDS": 13.823249904224234, "SUTENT": 3.584780584242671, "VOTRIENT": 1.108983907630945, "XELJANZ": 2.015264038644923, "XYREM": 1.935280626002884, "ZOSTAVAX": 2.2175998117468003, "null": 2.645297048125697}
\ No newline at end of file
+{"ASPARAGINASE": 115.37471484915706, "BUSULFAN": 32.68016446160553, "CELLCEPT": 10.555170474750588, "CICLOSPORIN": 10.211939015853826, "FENTANYL": 6.013566921823695, "VEKLURY": 114.71299213605796, "null": 0.8046059334572725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3669.json
index 7c9e9a4c686..e0af7979944 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3669.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3669.json
@@ -1 +1 @@
-{"COMIRNATY": 2.0101434360554293, "COVID19": 1.4805318037121844, "PEGASYS": 3.2380903027789647, "SPIKEVAX": 1.275677820968849, "VAXZEVRIA": 5.0012562282893}
\ No newline at end of file
+{"ALEMTUZUMAB": 14.821361568667095, "AXICABTAGENE": 56.71476246147901, "AZATHIOPRINE": 3.615386833547456, "BUSULFAN": 6.477690712140417, "CAELYX": 14.31536208390516, "CARMUSTINE": 31.67731317669775, "CELLCEPT": 17.507014253129213, "CICLOSPORIN": 10.923628415367586, "CIMZIA": 0.6702553917141636, "CLOPIDOGREL": 1.2812902852125518, "COMIRNATY": 0.0720805942174998, "CYTARABINE": 33.22414470690555, "DEXAMETHASONE": 12.249817780774288, "DOXORUBICIN": 34.81941064044349, "EPCORITAMAB": 159.19376077073815, "JAKAVI": 10.125944857806116, "KYMRIAH": 281.69919468589995, "LENALIDOMIDE": 28.23179277829084, "METHOTREXATE": 4.252831757282672, "MYCOPHENOLATE": 6.305544363025444, "OBINUTUZUMAB": 16.381827453046256, "OFATUMUMAB": 96.02542075337604, "POLATUZUMAB": 173.55008313044877, "RITUXIMAB": 32.97525118432485, "SIMPONI": 1.6407542220138915, "SPIKEVAX": 0.0542273837699254, "TACROLIMUS": 9.65208618744716, "TISAGENLECLEUCEL": 116.7143615763726, "YESCARTA": 88.44877055912738, "null": 0.2634860284851629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/367.json
index 793464bb428..9ba3f5d6c8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/367.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/367.json
@@ -1 +1 @@
-{"null": 1.6040519479099495}
\ No newline at end of file
+{"ABILIFY": 7.278328635002231, "AERIUS": 8.812578498017116, "AFINITOR": 0.1987530630036574, "AIMOVIG": 0.1266763642196769, "ANTIBIOTICS": 4.091737896443417, "APIDRA": 0.8528231977336327, "ARIPIPRAZOLE": 4.1045713440188525, "ATRIPLA": 0.0524649149120606, "AVAMYS": 0.6687802233751194, "AVANDIA": 0.1286757035547631, "AXURA": 11.30751142083474, "BEDAQUILINE": 0.819945316508704, "BENLYSTA": 0.2832781295921731, "BIKTARVY": 1.1074866639254344, "BLINDED": 14.535234038188143, "BOCEPREVIR": 2.9183720884033093, "BRINTELLIX": 5.00494041959586, "BRIVARACETAM": 13.718824718970282, "BRIVIACT": 21.39616270142542, "BUDESONIDE": 0.4136423264460874, "BUMETANIDE": 4.057387510271644, "BUPRENORPHINE": 2.1634620876394983, "CANNABIDIOL": 4.859331363345334, "CARBIDOPA": 1.7416240032459538, "CARFILZOMIB": 1.4734053275891004, "CARIPRAZINE": 10.926777059125843, "CELLCEPT": 0.1915411877794784, "CELSENTRI": 3.2454797414966223, "CHAMPIX": 20.10842703355831, "CIRCADIN": 5.947004397993815, "CLOPIDOGREL": 0.3353889750505089, "COMBIVIR": 0.9210776770026032, "COMIRNATY": 0.0478227950029255, "COMTAN": 3.213791618459928, "CYMBALTA": 3.4399732612646696, "DELAMANID": 1.3772291808432593, "DESLORATADINE": 2.2133642558313658, "DEXAMETHASONE": 0.2674122222899581, "DULOXETINE": 1.8970051573462343, "EBIXA": 11.19836694141282, "ELIQUIS": 0.0912932384183589, "ENTRESTO": 0.2388081825773419, "EPCLUSA": 0.7418305747649967, "EPIDYOLEX": 15.259360716774268, "EXELON": 8.75118043909636, "EXFORGE": 0.6897420409520536, "FENTANYL": 1.2057385167755472, "FYCOMPA": 54.633926663663935, "GARDASIL": 0.3232335897569908, "HARVONI": 0.4421407854064007, "HIZENTRA": 0.3021690142950512, "HUMALOG": 0.2511489514179428, "IBUPROFEN": 1.2321412958692184, "INCIVO": 0.9183264888257324, "INSULIN": 0.3443488314685572, "INTRONA": 4.181127741410827, "INVEGA": 7.991755507224294, "JANUMET": 0.2009802207381241, "JANUVIA": 0.180669666624231, "JARDIANCE": 0.2182321810221479, "KAFTRIO": 3.909029594468468, "KALETRA": 0.5778432641950023, "KEPPRA": 14.27825035064523, "KEYTRUDA": 0.0562385747279348, "KUVAN": 4.067437477392114, "LACOSAMIDE": 5.456948478188613, "LANTUS": 0.3404936394889655, "LATUDA": 6.252346600649236, "LEVETIRACETAM": 12.187562621272214, "LEVODOPA": 2.058743224429961, "LEVOFLOXACIN": 0.3989799679580866, "LURASIDONE": 13.398758145226614, "LYRICA": 2.502177153844869, "MELATONIN": 4.9935096143109, "MEMANTINE": 15.149752151390114, "MICARDIS": 0.5628216098615834, "MIDAZOLAM": 2.5614368868521877, "MMRVAXPRO": 0.3340721490772789, "NOT": 0.906566461636726, "OLANZAPINE": 6.049375478457449, "OLYSIO": 1.472116294728236, "OXYBUTYNIN": 1.6353939497558545, "PANTOPRAZOLE": 1.1943891536883848, "PEGASYS": 1.6806503266766637, "PEGINTERFERON": 1.3203564572556528, "PEGINTRON": 3.2070435027517714, "PERAMPANEL": 33.183438752010844, "PLAVIX": 0.0831758612891562, "PREGABALIN": 4.570798691404058, "REAGILA": 5.598032410133944, "REBETOL": 1.9972835741510917, "RIBAVIRIN": 0.6440548767961731, "RISPERIDONE": 4.053013405625042, "SIFROL": 5.269033713701167, "SILDENAFIL": 0.6701628575735804, "SLENYTO": 75.87874501894635, "SOVALDI": 0.690909524858509, "SPIKEVAX": 0.0474440660749503, "STALEVO": 4.866415552809968, "STELARA": 0.1594758027777244, "SUBOXONE": 1.1652151483087316, "SUTENT": 0.1287383475104149, "SYCREST": 1.9386642975192327, "TAMIFLU": 3.032944017602504, "TESTOSTERONE": 4.498486436025834, "TIVICAY": 1.6266201646975995, "TOVIAZ": 0.4726516288111599, "TOZINAMERAN": 0.0795335435965616, "VARENICLINE": 4.815008733020612, "VAXZEVRIA": 0.0195581568002345, "VFEND": 0.3959482028979511, "VIAGRA": 0.8355924988129425, "VIMPAT": 7.013525434769154, "VORICONAZOLE": 0.905746804293182, "WAKIX": 8.930435894476338, "XOLAIR": 0.2905210838511191, "XTANDI": 0.1742642734721207, "XYREM": 0.9777763090466896, "ZYPADHERA": 7.693713985210725, "ZYPREXA": 4.120879718859056, "null": 2.691785997336555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3670.json
index 5f44553b6a9..9acc243d26e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3670.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3670.json
@@ -1 +1 @@
-{"EXJADE": 93.84489672779354, "JAKAVI": 88.3270206100171}
\ No newline at end of file
+{"CAELYX": 20.610196016135923, "CARMUSTINE": 205.6403978976627, "CYTARABINE": 109.84257728385565, "DEXAMETHASONE": 25.35581415392435, "DOXORUBICIN": 101.48669010949072, "KYMRIAH": 376.9993592030765, "MABTHERA": 49.93232641021019, "METHOTREXATE": 8.063549626114202, "OFATUMUMAB": 218.4133132089203, "RITUXIMAB": 65.46921452981843, "YESCARTA": 37.29693213465015, "null": 0.054974960728461}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3671.json
index c0d66ed1380..f9dc234722d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3671.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3671.json
@@ -1 +1 @@
-{"ELIQUIS": 31.158359845470763}
\ No newline at end of file
+{"CAELYX": 103.41626631044566, "CANCIDAS": 163.16228952500327, "CARMUSTINE": 69.82304652318464, "CYTARABINE": 114.89787607503868, "DEXAMETHASONE": 26.661096797454302, "DOXORUBICIN": 94.08617766340936, "KYMRIAH": 125.3572413811146, "RITUXIMAB": 53.65627949750675, "null": 0.0771521218977836}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3672.json
index 0bfffd7e179..c48b2e85c64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3672.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3672.json
@@ -1 +1 @@
-{"BRILIQUE": 5.188762209688972, "BUDESONIDE": 7.928519619769921, "CLOPIDOGREL": 14.623208397234476, "ELIQUIS": 11.743825285805633, "ENOXAPARIN": 8.054653957046709, "NEXAVAR": 4.453077289386711, "NOVOSEVEN": 27.37382281177756, "PLAVIX": 8.13287277779388, "PRADAXA": 29.608454478081047, "SPRYCEL": 9.280297829664793, "TICAGRELOR": 11.45930800695112, "XARELTO": 20.66909927323392, "null": 1.4515004807243643}
\ No newline at end of file
+{"CICLOSPORIN": 23.061362074730244, "JAKAVI": 67.63130154274111, "RITUXIMAB": 49.50266585958754, "null": 0.1786799793800132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3673.json
index 02c28457cac..666cd9984a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3673.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3673.json
@@ -1 +1 @@
-{"CABOMETYX": 23.05397569835138, "DOCETAXEL": 10.752739606272568, "HERCEPTIN": 5.160034083773915, "OPDIVO": 2.031473398392185, "PAZOPANIB": 69.88264006999313, "SUNITINIB": 30.246649169899676, "SUTENT": 40.61551697744172, "VOTRIENT": 94.5611094490942, "null": 1.1353987439852593}
\ No newline at end of file
+{"null": 0.7326587296750037}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3674.json
index 63b3dfc4946..c3eb7402588 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3674.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3674.json
@@ -1 +1 @@
-{"IBRANCE": 6.901600712864602, "SUTENT": 2.4481902326794844, "null": 1.976770153810471}
\ No newline at end of file
+{"COMIRNATY": 1.175796577999735, "null": 0.5914967197394623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3675.json
index 53f0563d76d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3675.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3675.json
@@ -1 +1 @@
-{"ANAKINRA": 239.867692138681}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3676.json
index 80a99986ee0..dd5b7974391 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3676.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3676.json
@@ -1 +1 @@
-{"AUBAGIO": 2.037738115535753, "CICLOSPORIN": 1.3296053076815124, "FASLODEX": 2.4907961937178054, "FORSTEO": 2.7084564208969177, "GARDASIL": 1.0097729474717771, "IBRANCE": 2.8969949912489854, "TESTOSTERONE": 28.50880331471912, "XELJANZ": 2.56609689130473, "null": 2.917848069074385}
\ No newline at end of file
+{"CAPECITABINE": 181.5804645448182, "XELODA": 558.2720644150886, "null": 1.00126318400449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3677.json
index c457f182046..616457c7093 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3677.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3677.json
@@ -1 +1 @@
-{"null": 1.4712875473048062}
\ No newline at end of file
+{"null": 6.781126114714091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3678.json
index 6762db13110..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3678.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3678.json
@@ -1 +1 @@
-{"AUBAGIO": 7.692317511429761, "DOCETAXEL": 19.602769801409373, "GARDASIL": 1.656553702329182, "HERCEPTIN": 9.952475578000737, "IBRANCE": 6.1718156956636845, "NEXAVAR": 1.8493915291871448, "PEGASYS": 1.6204524808962786, "PEGINTRON": 2.5563502465571144, "SUTENT": 2.6623286320253694, "null": 2.470081556627413}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3679.json
index 488626f03bf..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3679.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3679.json
@@ -1 +1 @@
-{"null": 10.633026989774171}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/368.json
index 6855e3ebe3b..66bfb39c80b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/368.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/368.json
@@ -1 +1 @@
-{"COMIRNATY": 5.957808206726362}
\ No newline at end of file
+{"CHAMPIX": 28.458013389646744, "OLANZAPINE": 36.114382596059535, "null": 1.0370250901857163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3680.json
index 37dabfa498c..579677da8cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3680.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3680.json
@@ -1 +1 @@
-{"CLADRIBINE": 1196.8137419501625}
\ No newline at end of file
+{"ARIPIPRAZOLE": 32.39399682204394, "ENTRESTO": 13.473400645138348, "null": 1.757132422305859}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3681.json
index befbe3b3070..d91f192fe07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3681.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3681.json
@@ -1 +1 @@
-{"CLADRIBINE": 4039.7874875360335}
\ No newline at end of file
+{"null": 0.4268472894223336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3682.json
index eae52807c42..2dc08a66759 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3682.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3682.json
@@ -1 +1 @@
-{"ABILIFY": 1.954221825811256, "ADVAGRAF": 2.718963281340096, "AERIUS": 2.6019695466685318, "APIXABAN": 4.222756005850279, "ARIPIPRAZOLE": 1.2157566475382076, "AXURA": 8.504855877447458, "AZILECT": 14.574263652342466, "BENZODIAZEPINE": 1.6606382481186632, "BEXTRA": 2.919419191066829, "BIKTARVY": 1.5037205459401386, "BRINTELLIX": 1.4843907049321108, "BRIVARACETAM": 4.337772292008388, "BRIVIACT": 2.119041677049975, "BUPRENORPHINE": 2.484367839538232, "CANCIDAS": 1.2542906049171672, "CANNABIDIOL": 1.374831979862992, "CARBIDOPA": 10.349545374123627, "CELECOXIB": 1.383977065234524, "CHAMPIX": 5.764329417508332, "CIRCADIN": 2.4172366783909487, "CLOPIDOGREL": 1.831310761905845, "COMTAN": 20.257883233955383, "COMTESS": 7.980632661421253, "CRESEMBA": 2.2399277868072978, "CYMBALTA": 2.638617974935465, "DELAMANID": 1.3580551210675482, "DESLORATADINE": 1.6032002424352905, "DEXAMETHASONE": 1.0105613790497538, "DULOXETINE": 1.5999801629409287, "EBIXA": 9.62757607162916, "ENTACAPONE": 8.190409346291263, "EXELON": 9.084379473408289, "FENTANYL": 1.5673430090405664, "FYCOMPA": 3.0691786676542123, "INVANZ": 19.473425428213435, "INVEGA": 1.6020692512188266, "KALETRA": 1.2560296862391165, "KEPPRA": 3.261779059277813, "LATUDA": 4.676230114320489, "LEVETIRACETAM": 1.5900174562942062, "LEVODOPA": 10.923715051688882, "LEVOFLOXACIN": 1.7332415922203497, "LYRICA": 3.016653610318668, "MELATONIN": 3.950953057873376, "MEMANTINE": 3.1470164016387168, "MIDAZOLAM": 3.127397232006629, "NEUPRO": 10.668591887877795, "NOXAFIL": 1.3730936616865106, "OCRELIZUMAB": 1.485852674580468, "OLANZAPINE": 2.0077639336146538, "ONGENTYS": 24.397770380650236, "OSELTAMIVIR": 4.045122864211468, "OXYBUTYNIN": 5.711367998435299, "PALIPERIDONE": 4.432568208933654, "PEGASYS": 1.1349993684549675, "PEGINTRON": 1.8876001029688323, "PRAMIPEXOLE": 20.583403914815182, "PREGABALIN": 1.385167745986436, "PRIALT": 9.680678579928584, "PROPRANOLOL": 1.3426920458236802, "RANEXA": 3.229017383635012, "RANOLAZINE": 5.94244126177556, "REVLIMID": 1.3812367962644043, "RISPERIDONE": 1.692068752229236, "SIFROL": 17.357361828954794, "STALEVO": 14.215252239620208, "SUBOXONE": 3.2101557455328, "SUSTIVA": 4.280479504365571, "TAMIFLU": 20.317079053973675, "TOVIAZ": 1.6285580683594771, "VFEND": 39.9247386582293, "VIMPAT": 2.0653796496900183, "VORICONAZOLE": 22.376448887865354, "XTANDI": 1.53363934379061, "XYREM": 3.638520376701773, "ZYPADHERA": 1.9351871306900024, "ZYPREXA": 2.159350643355357, "null": 2.418073440833141}
\ No newline at end of file
+{"null": 3.2210629451300137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3683.json
index 04d24606de3..645da7bd7f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3683.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3683.json
@@ -1 +1 @@
-{"ABILIFY": 15.51193521210926, "AERIUS": 5.613270771771385, "ANTIBIOTICS": 7.925452504116055, "ARIPIPRAZOLE": 26.46381726033198, "BIKTARVY": 1.0954206674250555, "BRINTELLIX": 3.147963428973497, "BRIVIACT": 6.941085502194045, "BUPRENORPHINE": 2.493256477463464, "CANAGLIFLOZIN": 31.4351166178976, "CARBIDOPA": 12.768091093250442, "CARIPRAZINE": 31.807090427007594, "CHAMPIX": 6.408686197751896, "CYMBALTA": 2.537637266925037, "DULOXETINE": 3.1190872412376005, "FYCOMPA": 5.23944941306573, "INVEGA": 17.692620719746742, "ISENTRESS": 3.1728835138025038, "KEPPRA": 3.9479046521429058, "LATUDA": 30.601852506935607, "LEVETIRACETAM": 2.837230167116293, "LEVODOPA": 11.089738228310518, "LURASIDONE": 35.75094149436588, "LYRICA": 1.1980049140596092, "OLANZAPINE": 12.94495663122712, "PEGASYS": 1.9904111992467577, "PEGINTRON": 1.8428152786250465, "PROPRANOLOL": 3.7947746908639264, "RISPERIDONE": 14.608692375920151, "SIFROL": 6.003134274361014, "STALEVO": 3.80876539209585, "SUBOXONE": 4.223326806788521, "TAMIFLU": 11.95068004286625, "VFEND": 21.164207312631717, "VIMPAT": 3.284362503392343, "VORICONAZOLE": 12.79315998657443, "ZYPADHERA": 3.010679029354051, "ZYPREXA": 6.832288572019277, "null": 1.975698307319549}
\ No newline at end of file
+{"AFINITOR": 1.0720456827806797, "APIXABAN": 4.247569388329317, "ASPARAGINASE": 5.250312001542403, "AVANDAMET": 21.715518874769412, "AVANDIA": 24.4372415832342, "AVASTIN": 1.9213595171174265, "BETAFERON": 6.03127253524514, "CAELYX": 6.819344488332185, "COMIRNATY": 0.4333597831405736, "CYMBALTA": 0.388694736512155, "DEXAMETHASONE": 1.3053965871129014, "DOCETAXEL": 2.767484724194341, "DOXORUBICIN": 5.365205940480204, "EFAVIRENZ": 9.576896828081043, "ELIQUIS": 0.5920372577420342, "EMTRICITABINE": 8.613779352798565, "ENTRESTO": 14.265133013679788, "HERCEPTIN": 8.500444015601486, "IVABRADINE": 92.9027951113865, "KEYTRUDA": 0.6854705142457148, "LAMIVUDINE": 9.535679925356042, "OLANZAPINE": 0.823395358229013, "PANTOPRAZOLE": 3.2643578456119187, "PEGASYS": 1.238918023894754, "PEGINTRON": 1.0200369012663737, "RITUXIMAB": 1.6209058107108156, "SIMPONI": 1.0451538813990011, "SOLIRIS": 1.362847689350415, "SPIKEVAX": 0.3468224104534395, "STELARA": 3.834585435148072, "SUTENT": 1.4530718112413126, "TAGRISSO": 3.147025142157053, "TOZINAMERAN": 0.1964784967947991, "VALSARTAN": 17.279783813971164, "VAXZEVRIA": 0.1236826443923081, "XOLAIR": 1.3006379368869951, "ZYPREXA": 0.7963980843145411, "null": 0.8469869171946219}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3684.json
index 6a0d5d4427a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3684.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3684.json
@@ -1 +1 @@
-{"TOZINAMERAN": 1.6426077594751765, "null": 1.2572189361171209}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3685.json
index b0537d2dbc0..80ee148ee49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3685.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3685.json
@@ -1 +1 @@
-{"null": 1.561918659840594}
\ No newline at end of file
+{"null": 1.3795944005902652}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3686.json
index fcce64a124d..37cb9d181f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3686.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3686.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 79.60494627119607, "LEVODOPA": 659.9624101125918, "null": 1.295121185026099}
\ No newline at end of file
+{"ATAZANAVIR": 7.3721153860807, "COMIRNATY": 1.0005889001509047, "ENOXAPARIN": 6.879901814669852, "FENTANYL": 3.264637075946964, "FORSTEO": 2.16844663818829, "GARDASIL": 7.928637210571082, "SHINGRIX": 2.130127421609234, "SPIKEVAX": 0.8316668595964257, "SUTENT": 0.6762261184248943, "TOZINAMERAN": 1.0405989915724552, "VAXZEVRIA": 1.152211230765587, "XTANDI": 1.7553876703679228, "ZOSTAVAX": 1.6770257724300308, "null": 0.9614331445323094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3687.json
index 2857f3012b0..86cdc2a9c7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3687.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3687.json
@@ -1 +1 @@
-{"ABILIFY": 2.330773930251467, "AERIUS": 3.322449323183662, "ARIPIPRAZOLE": 4.871560546516728, "AZILECT": 25.5602279768312, "BRINTELLIX": 1.509944918047115, "BRIVARACETAM": 4.354156378080129, "BRIVIACT": 4.108361007717854, "BUPRENORPHINE": 2.118331411614356, "CANAGLIFLOZIN": 19.81392393494083, "CARBIDOPA": 19.09481674621866, "CHAMPIX": 3.9217213864839504, "COMTAN": 27.14727310831451, "CYMBALTA": 2.005727838390822, "DELAMANID": 2.828570343338615, "DULOXETINE": 2.1632417339479155, "EBIXA": 10.993170097526582, "ENTACAPONE": 30.772711995753465, "ESOMEPRAZOLE": 1.2074277513657792, "EVENITY": 1.2974930212690103, "FYCOMPA": 6.176800216476574, "KEPPRA": 3.675635395878644, "LACOSAMIDE": 1.7004806449034184, "LATUDA": 3.087308699109023, "LEVETIRACETAM": 3.391483978688039, "LEVODOPA": 34.39880764038122, "LEVOFLOXACIN": 2.511103063728401, "LYRICA": 3.1899930063484985, "MELATONIN": 4.104160179098392, "MEMANTINE": 5.846093479961975, "MIDAZOLAM": 1.0461354833740852, "NEUPRO": 26.680345183922075, "NOXAFIL": 3.4786890835323323, "OLANZAPINE": 3.3036845719371994, "OXYBUTYNIN": 2.3935303441415026, "PEGASYS": 1.0834814088975495, "PIOGLITAZONE": 65.54495287783573, "POSACONAZOLE": 5.696964522562297, "PREGABALIN": 2.5856107724894604, "PROPRANOLOL": 3.5535107060293467, "RANEXA": 6.560073753302664, "RANOLAZINE": 5.168106004558706, "RISPERIDONE": 5.512040834318139, "SIFROL": 27.067351593524997, "STALEVO": 20.04913758685486, "SUBOXONE": 2.739589857014244, "TAMIFLU": 6.762625765982687, "VFEND": 59.75643232354208, "VIMPAT": 2.800729348188799, "VORICONAZOLE": 44.81446573287334, "YESCARTA": 1.264904883577879, "ZYPADHERA": 2.544636836470833, "ZYPREXA": 1.6673416909504095, "null": 2.67856468673834}
\ No newline at end of file
+{"ABACAVIR": 5.919992515891461, "ABILIFY": 1.1468560258026446, "ADALIMUMAB": 0.3554306816479534, "AFINITOR": 0.2346000003758437, "AIMOVIG": 0.7002274769074485, "ALEMTUZUMAB": 2.3490437021388693, "APIDRA": 0.6764830232964144, "APIXABAN": 13.505811596113965, "ARAVA": 0.1073290732319436, "ATAZANAVIR": 5.3712663114681645, "AUBAGIO": 2.290242975455316, "AZATHIOPRINE": 0.5854967599694517, "AZILECT": 4.4984197913379145, "BETAFERON": 1.9599947742206745, "BRINTELLIX": 0.8021673914752893, "BRIVIACT": 4.293936965457269, "BUPIVACAINE": 4.694354506375283, "BUPRENORPHINE": 0.5390791517583937, "BYDUREON": 0.6220934501821923, "BYETTA": 0.323662094639556, "CHAMPIX": 1.0724050269404148, "CICLOSPORIN": 0.9210923001273502, "CIMZIA": 0.3020866296502894, "CLOPIDOGREL": 0.2770121858845202, "COMIRNATY": 0.8529104384488553, "COSENTYX": 0.2936760693263598, "CRIXIVAN": 8.567519225773303, "CYMBALTA": 0.7678765899406257, "CYTARABINE": 0.6327170064308908, "DEXAMETHASONE": 0.811277756329189, "ELIQUIS": 0.7072577147517999, "ENFUVIRTIDE": 28.971876298800037, "EVISTA": 1.034030684383437, "EXFORGE": 1.518787026199993, "EYLEA": 1.3524158002329294, "FAMPYRA": 1.0954507105618807, "FIRDAPSE": 6.9382630421549285, "FORSTEO": 0.3813011317498052, "FYCOMPA": 5.439592715976101, "GARDASIL": 2.1760861979223804, "HUMALOG": 0.4956810627840284, "HUMIRA": 0.9003082503338713, "IBRANCE": 0.4998057048425135, "INLYTA": 0.5733365302472182, "INSULIN": 0.3329280520100712, "IPILIMUMAB": 0.8825308137619671, "JANUVIA": 0.5324982312971084, "JARDIANCE": 0.2587619750938802, "KALETRA": 0.6170948850003347, "KEPPRA": 3.1217027153064847, "KESIMPTA": 1.9677009128754703, "KEYTRUDA": 1.158756765660363, "LACOSAMIDE": 13.4681378783447, "LANTUS": 0.549054483036935, "LATUDA": 0.5902066527343632, "LEMTRADA": 2.382423991014396, "LEVEMIR": 0.5924151013210224, "LEVETIRACETAM": 1.1464987271890283, "LEVOFLOXACIN": 0.5680093628383226, "LYRICA": 3.0515211474497232, "MAVENCLAD": 2.2739132560226696, "METHOTREXATE": 0.2359857468305322, "MICARDIS": 0.586703664080672, "MODERNA": 0.4479129423517426, "NEXAVAR": 0.2640159777228409, "NIMENRIX": 1.2598235311976809, "NUCALA": 0.3125355109717602, "OLANZAPINE": 0.6761876972747718, "OMALIZUMAB": 0.6149687963623927, "OPDIVO": 1.3608345521610683, "OPSUMIT": 0.2282734787971796, "PEGASYS": 0.7382777204615255, "PEGINTRON": 0.9703369846008792, "PLAVIX": 0.3145636308486658, "PLEGRIDY": 0.8629205228918957, "PREGABALIN": 1.2181614399579554, "PRIVIGEN": 0.7225892224795046, "REVATIO": 0.8924182611817462, "SAQUINAVIR": 79.86579112512173, "SHINGRIX": 0.961871872949421, "SIFROL": 4.799839783460544, "SILDENAFIL": 1.1379669214104569, "SIMPONI": 0.5132848456134002, "SOLIRIS": 0.7160302306476665, "SPIKEVAX": 0.7995956522673986, "STELARA": 0.3872178172614714, "SUTENT": 0.254757426541169, "TAMIFLU": 1.413516354289993, "TASIGNA": 0.968768595508248, "TOVIAZ": 1.495075404600768, "TOZINAMERAN": 1.1871224006353769, "TRELEGY": 0.540361464486722, "TRULICITY": 0.6038878397384363, "TWINRIX": 2.0188113571126785, "VAXZEVRIA": 0.8126268333683263, "VFEND": 4.40832791286407, "VIAGRA": 2.652691510145827, "VIMPAT": 14.679877043416138, "VORICONAZOLE": 1.324956266075758, "VOTRIENT": 0.2813257208109511, "XALKORI": 1.293384647039901, "XELJANZ": 0.2412214802934003, "XOLAIR": 0.3362390743054551, "XTANDI": 1.1403238912060802, "ZOSTAVAX": 1.6472636039183786, "ZYPREXA": 0.6964070222382774, "null": 1.1119007059692276}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3688.json
index 204284e0c38..00cd787f4a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3688.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3688.json
@@ -1 +1 @@
-{"ABILIFY": 43.53443381646376, "ARIPIPRAZOLE": 10.30444529928772, "CHAMPIX": 5.490112050956109, "CYMBALTA": 1.469034789297018, "KEPPRA": 1.5279667992746049, "LEVETIRACETAM": 7.0931842792459125, "LYRICA": 2.994477298127325, "OLANZAPINE": 1.930952446502496, "OXYBUTYNIN": 16.87351985190282, "PEGINTRON": 1.5365378663140898, "TAMIFLU": 7.224798356858723, "VFEND": 8.80196688735411, "VORICONAZOLE": 14.197228302801186, "ZYPREXA": 2.657407961420685, "null": 2.567604466216125}
\ No newline at end of file
+{"SAXENDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3689.json
index 26540abce9e..cee688fdace 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3689.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3689.json
@@ -1 +1 @@
-{"VFEND": 187.24760436163928, "VORICONAZOLE": 56.02069897689224, "null": 1.0888301990263314}
\ No newline at end of file
+{"ABATACEPT": 11.792513734963494, "ABILIFY": 2.2388537617035595, "ADALIMUMAB": 11.014695245370092, "ALEMTUZUMAB": 2.218022916328872, "APIDRA": 4.110255914640782, "APREMILAST": 3.594502714886528, "ARAVA": 1.9923206581457529, "ATRIPLA": 0.1616683067560348, "AUBAGIO": 1.8476648060445215, "AVANDIA": 2.575245743437605, "BENLYSTA": 2.911525200322367, "BUPRENORPHINE": 0.7334357895460243, "BYETTA": 0.740411815100034, "CIMZIA": 0.3012179661791569, "COMIRNATY": 0.0764641046967664, "COSENTYX": 1.9926594482458029, "CYMBALTA": 0.6458944148399233, "DEXAMETHASONE": 0.7022848613427917, "ELIQUIS": 0.4893956968690163, "ENBREL": 2.6446755302296987, "ENTYVIO": 1.4645925185507982, "FENTANYL": 0.9822312836886302, "GARDASIL": 1.065546007474289, "HUMALOG": 0.8929873139811246, "HUMIRA": 3.234182918361172, "INSULIN": 1.226523957483306, "JARDIANCE": 0.7468405002099641, "KEPPRA": 2.727021595603889, "LANTUS": 14.961341153306725, "LEMTRADA": 1.3373097511307472, "LEVEMIR": 9.67096661392577, "LYRICA": 1.5955117253814468, "NUCALA": 0.498403766069805, "OPSUMIT": 0.8409656208943492, "OPTIMARK": 0.7245532664768891, "OZEMPIC": 8.75058274214842, "PEGASYS": 0.3195782538052187, "PEGINTRON": 0.4952451865906424, "PLAVIX": 0.8448732843104335, "SAXENDA": 3.019790070550251, "SPIKEVAX": 0.0869102444213818, "STELARA": 1.9644144141735869, "SUBOXONE": 4.503276277195378, "TOUJEO": 14.68356855096157, "TOZINAMERAN": 0.1143063085842615, "TRELEGY": 3.3710901238957205, "TREMFYA": 3.355216252148965, "TRESIBA": 4.774194496862323, "TRUVADA": 0.1438002270623616, "TWINRIX": 4.081461293896608, "VAXZEVRIA": 0.0715363237222739, "VICTOZA": 5.528040881811376, "ZYPREXA": 1.0731743339413071, "null": 1.3444814426291405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/369.json
index 2eef2e1d1ba..6dca8ae7ac9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/369.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/369.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7779437620598966, "null": 2.147345400553251}
\ No newline at end of file
+{"ABASAGLAR": 1.1308823610004233, "ABILIFY": 3.3478395745522658, "AERIUS": 2.5846290667613965, "AFINITOR": 0.0817427237004543, "AIMOVIG": 0.0740579314261094, "ALL": 1.680673303578926, "ANTIBIOTICS": 3.16552049140356, "APIDRA": 0.6045077726014509, "APIXABAN": 0.1004553277977778, "ARAVA": 0.0507226178211601, "ARIPIPRAZOLE": 4.19631282388288, "ARSENIC": 7.903658225681238, "ATRIPLA": 0.0278468578827032, "AUBAGIO": 0.1001128599224931, "AVAMYS": 0.1557438960386421, "AVANDIA": 0.0761326383692126, "AZILECT": 2.919359540835329, "BEDAQUILINE": 0.3372140477004774, "BENLYSTA": 0.2059662025094197, "BENZODIAZEPINE": 2.5765772321480163, "BENZODIAZEPINES": 7.723144039330642, "BIKTARVY": 0.5340908279854705, "BLINDED": 5.973381414487798, "BORTEZOMIB": 1.2749451728167571, "BOSULIF": 0.6154172079343123, "BRIDION": 0.5801786212395429, "BRILIQUE": 0.2392688720510016, "BRINTELLIX": 4.180714102724107, "BRIVARACETAM": 1.7074767988389716, "BRIVIACT": 3.67304783014517, "BUDESONIDE": 0.5269257009086187, 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3.947008318390966, "STELARA": 0.1648023157679644, "STRIBILD": 0.0738937020248788, "SUBOXONE": 1.532400044242466, "SUFENTANIL": 1.193864221690644, "SUSTIVA": 3.851180370650725, "SUTENT": 0.2381634930695639, "SYCREST": 3.840086729726572, "SYNAGIS": 0.415750515422821, "TACROLIMUS": 0.7650543817770928, "TAMIFLU": 5.3963347810506255, "TICAGRELOR": 0.4726762201360995, "TIVICAY": 1.1926544990608925, "TOVIAZ": 0.4151859177282936, "TOZINAMERAN": 0.2086026935752955, "TRACLEER": 0.1810619898093902, "TRELEGY": 0.1486343248150417, "TRIUMEQ": 1.2389470483131992, "VALDOXAN": 2.680986286067177, "VARENICLINE": 5.759763586746183, "VAXZEVRIA": 0.1270526607849892, "VFEND": 2.5421991362655345, "VIAGRA": 0.3477255706454413, "VIMPAT": 3.1788310313852857, "VORICONAZOLE": 2.004671025241877, "VOTRIENT": 0.2208649377888981, "XELJANZ": 0.149352267303682, "XOLAIR": 0.1922658744983055, "XTANDI": 0.1470301836286301, "XYREM": 4.6827162084615965, "YESCARTA": 2.888920676884368, "ZOSTAVAX": 0.1435100604607812, "ZYPADHERA": 16.09520139701912, "ZYPREXA": 4.668850229763304, "null": 2.777693816270886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3690.json
index 885cd7e549a..a92660b5c03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3690.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3690.json
@@ -1 +1 @@
-{"null": 1.3429555258382595}
\ No newline at end of file
+{"JANUVIA": 47.95484363882093, "METHOTREXATE": 149.24665081034198, "null": 0.8199878883525422}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3691.json
index 58ff105d77e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3691.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3691.json
@@ -1 +1 @@
-{"ABATACEPT": 15.581628363004784, "ACETAMINOPHEN": 36.31596680891196, "ADALIMUMAB": 32.18466224308178, "AMINOSALICYLIC": 1.6449625185112382, "ANAKINRA": 6.272781466344495, "APREMILAST": 13.597033352859649, "APREPITANT": 45.12003483895201, "ARAVA": 57.71582471304931, "BELIMUMAB": 14.616996410922086, "CERTOLIZUMAB": 11.065622066544838, "CIMZIA": 4.25835228837303, "COSENTYX": 1.498115076149129, "CYMBALTA": 1.2277894383661172, "ENBREL": 1.7187582781676367, "ERELZI": 7.842053637448715, "HUMIRA": 1.7270065114858395, "LEFLUNOMIDE": 6.888812585821236, "RITUXIMAB": 2.625865196199946, "XELJANZ": 1.7471611991287883}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3692.json
index 93dff94922a..3027d20c066 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3692.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3692.json
@@ -1 +1 @@
-{"CAPECITABINE": 19.68713291527521, "COMIRNATY": 2.3111801825308653, "PEGASYS": 2.356356897487794}
\ No newline at end of file
+{"COMIRNATY": 0.9270671998382858, "SPIKEVAX": 0.5888159021678265, "TOZINAMERAN": 1.387230069032512, "VAXZEVRIA": 0.6182462309798716, "null": 0.9425851729356828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3693.json
index b1ccb97cde8..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3693.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3693.json
@@ -1 +1 @@
-{"AIMOVIG": 1.142840853867678, "ATRIPLA": 37.6019804961547, "BUPRENORPHINE": 1.228818210743113, "EVISTA": 3.4995935053658225, "FORSTEO": 3.89901127226738, "IBRANCE": 1.0651162328366393, "ILARIS": 147.86954815353883, "KALETRA": 1.8652391711892768, "LANTUS": 1.687245599907236, "STRIBILD": 22.89031908264416, "SUBOXONE": 3.003159636396897, "TRUVADA": 18.44578937706576, "VIAGRA": 1.7040340847474071, "XELJANZ": 2.341637076322997}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3694.json
index 7b2b7bb2922..7d213d1d26f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3694.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3694.json
@@ -1 +1 @@
-{"null": 1.3496596646211332}
\ No newline at end of file
+{"CLOPIDOGREL": 11.345758274990828, "COMIRNATY": 0.174176073825283, "OLANZAPINE": 30.91820455866257, "PLAVIX": 6.520799210643893, "SUTENT": 1.7932819365641055, "TOZINAMERAN": 0.6474861547546252, "VAXZEVRIA": 0.6123118510975583, "null": 0.904229298143893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3695.json
index 400850782cf..d774767cac3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3695.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3695.json
@@ -1 +1 @@
-{"SUTENT": 5.539166213954836}
\ No newline at end of file
+{"ABASAGLAR": 1.2778022687549382, "ABATACEPT": 5.388689232694495, "ABILIFY": 0.1309086915798213, "ACETAMINOPHEN": 17.43727164043431, "ADALIMUMAB": 12.412684092523174, "AFINITOR": 0.3057382121296327, "AIMOVIG": 2.3317698309543617, "ALIMTA": 0.2308493865834257, "ANORO": 0.5065659131799106, "APIDRA": 0.4590178534785424, "APREMILAST": 9.890262784334508, "APREPITANT": 22.677592482980696, "ARANESP": 0.1388000917049452, "ARAVA": 12.537080677640091, "ATAZANAVIR": 0.313457740499912, "ATRIPLA": 0.0552062020854661, "AUBAGIO": 0.6565682809726952, "AVAMYS": 0.2229013120904579, "AVASTIN": 0.2097461504447801, "BEDAQUILINE": 0.3365150020319958, "BENLYSTA": 0.5429033458220477, "BETAFERON": 0.7073419728644481, "BEVACIZUMAB": 0.2004625153676748, "BIKTARVY": 0.2515511761003794, "BOTULINUM": 1.3133672325639618, "BRILIQUE": 0.2416533187532135, "BRINTELLIX": 0.5335627036937742, "BUDESONIDE": 0.1394908096129407, "BUPIVACAINE": 2.2299700644464067, "BUPRENORPHINE": 0.1771098071217339, "BYDUREON": 0.401950158640223, "BYETTA": 0.2142075481553918, "CABOTEGRAVIR": 2.866000603044311, "CAPECITABINE": 0.4122049752180266, "CELLCEPT": 0.2749925816438541, "CHAMPIX": 0.7052606349456971, "CICLOSPORIN": 0.2129141502995293, "CIMZIA": 1.7687939036438505, "CLOPIDOGREL": 0.3735762891390757, "COAPROVEL": 0.588605056523218, "COMIRNATY": 0.7600665317134219, "COSENTYX": 2.144955012412693, "CYMBALTA": 0.4626497249199467, "CYTARABINE": 0.126750785619144, "DEXAMETHASONE": 0.3735877088013007, "DOCETAXEL": 0.8469381030448893, "DOXORUBICIN": 0.5036246935250678, "DULOXETINE": 0.6084132104475929, "ELIQUIS": 0.3678141949532129, "EMPAGLIFLOZIN": 1.2616276076444737, "ENBREL": 0.419669846125789, "ENOXAPARIN": 0.3314208203179377, "ENTRESTO": 0.5974045120819164, "ENTYVIO": 0.6334181460488328, "ERELZI": 3.4395135456138357, "ESBRIET": 0.2760616847561514, "EVENITY": 0.4173023377545036, "EVISTA": 0.6044088855446622, "EXFORGE": 0.9051630790855396, "EXJADE": 0.2311724863101534, "EYLEA": 0.3599984783333053, "FASENRA": 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0.6494745896972541, "VIAGRA": 0.4760651638530888, "VICTOZA": 0.4398276587676169, "VOTRIENT": 0.2657130645145722, "XELJANZ": 0.5540887979719752, "XELODA": 0.6413031742025215, "XOLAIR": 0.7252214315111685, "XTANDI": 0.2911753290752918, "ZOSTAVAX": 0.5317349115336008, "ZYPADHERA": 0.7490333585649536, "ZYPREXA": 0.1104208544161542, "null": 0.5506724232451164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3696.json
index 80b5aaba0c6..3c076876e30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3696.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3696.json
@@ -1 +1 @@
-{"OLANZAPINE": 26.64269980674093, "null": 1.055977058825828}
\ No newline at end of file
+{"null": 0.915279293440222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3697.json
index ccff4ce598b..b19d2196a8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3697.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3697.json
@@ -1 +1 @@
-{"CHAMPIX": 3.3336090215114127, "COSENTYX": 2.1898544143979284, "COVID19": 3.909260378432904, "CYMBALTA": 4.0590169440219, "TOZINAMERAN": 3.37670128122167, "VAXZEVRIA": 1.2360322730890052, "XYREM": 15.869527954881004}
\ No newline at end of file
+{"BENLYSTA": 20.354368244169887, "NUCALA": 6.931725638503373, "XELJANZ": 28.66488865384152, "null": 1.9107834428730388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3698.json
index 9dcaacf96b3..7280012e75a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3698.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3698.json
@@ -1 +1 @@
-{"SOLIRIS": 420.6650807916568}
\ No newline at end of file
+{"CYTARABINE": 6.312276635523843, "HUMIRA": 4.189098240426601, "IBUPROFEN": 4.417866413052234, "ICLUSIG": 52.22913201027892, "JANUMET": 8.312565171500491, "JANUVIA": 4.790645945058527, "JARDIANCE": 4.560030511026739, "LANTUS": 3.333628785980831, "OPSUMIT": 18.524881403051054, "SOLIRIS": 6.432455918025368, "SUTENT": 1.2791138600712224, "TRACLEER": 24.96451421504545, "TRELEGY": 12.639203456448904, "null": 1.0606606525199376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3699.json
index 82e60b1b3c1..8888ab2e98a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3699.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3699.json
@@ -1 +1 @@
-{"CICLOSPORIN": 9.716280946140808, "COMBIVIR": 20.665057068757665, "JAKAVI": 9.252306126008834, "PRIVIGEN": 36.938125840309176, "RASBURICASE": 437.31840994707375, "SOLIRIS": 149.76344178660727}
\ No newline at end of file
+{"SHINGRIX": 165.6637547237272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/37.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/37.json
index 27f6aaa6532..7065186b2de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/37.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/37.json
@@ -1 +1 @@
-{"EYLEA": 15.953108738421426, "MEPOLIZUMAB": 11.515727471543787, "PEGINTRON": 2.084322590103024, "TOZINAMERAN": 1.2341114238773403, "null": 1.3769070282006957}
\ No newline at end of file
+{"AFINITOR": 1.062206827687452, "AIMOVIG": 1.4678936964867877, "ARAVA": 0.0393149496719138, "AUBAGIO": 0.9591676946079758, "AVASTIN": 2.074367710277325, "AZATHIOPRINE": 1.471752531613027, "BEMFOLA": 79.10508326271024, "BENLYSTA": 0.5482022604879712, "BUDESONIDE": 1.0935098876157023, "CELLCEPT": 0.5504820539732073, "CHAMPIX": 0.4040608704188936, "CICLOSPORIN": 1.2730081760810796, "CIMZIA": 0.2444530067412436, "CLOPIDOGREL": 1.6077705458355458, "COMIRNATY": 2.2595444499864263, "COSENTYX": 0.7322495900995969, "CYMBALTA": 0.150733411715725, "CYTARABINE": 0.7988481891795616, "DULOXETINE": 1.075366360659812, "ELIQUIS": 0.5008065789691838, "ELLAONE": 29.46956243178612, "ENOXAPARIN": 2.551243122979008, "ENTYVIO": 2.620234536739679, "ESMYA": 9.95289940394091, "ESOMEPRAZOLE": 2.093560023308759, "EXJADE": 0.9477413178279344, "FASLODEX": 0.4439118420356965, "FENTANYL": 0.5022326461733341, "FORSTEO": 0.6339831577208268, "GARDASIL": 3.4012786098137373, "GONALF": 8.566764922629247, "HUMIRA": 1.0800536465791513, "IBRANCE": 0.2396306879554818, "IBUPROFEN": 1.0794339221470042, "JANUVIA": 1.2837466753030689, "JARDIANCE": 1.8517668153918387, "KEPPRA": 0.2298740226440425, "KEYTRUDA": 0.189263394229059, "LANTUS": 0.1860812457308912, "LEVOFLOXACIN": 0.3012611967043738, "LONSURF": 1.854581787418916, "LUVERIS": 41.22377280101578, "MAYZENT": 53.635991976801535, "METHOTREXATE": 0.5430575913356483, "MODERNA": 0.5655080708208832, "NEULASTA": 0.7843488120064039, "NEXAVAR": 0.456090032629756, "NUCALA": 0.3526517211257751, "OPSUMIT": 0.4044067539165771, "ORGALUTRAN": 23.462033419613583, "OVITRELLE": 28.95095897584982, "PEGASYS": 0.3118406016485181, "PEGINTRON": 0.2542411533630444, "PLAVIX": 0.3971755318562495, "RITUXIMAB": 0.5674319802891328, "ROACTEMRA": 0.8976871296919455, "SAXENDA": 0.970691788197266, "SHINGRIX": 0.5099171063111496, "SIMPONI": 0.2278509062085023, "SPIKEVAX": 1.1766415976010594, "STELARA": 0.6253176456088303, "STIVARGA": 0.8207646931816424, "SUTENT": 0.5426942938111434, "TAMIFLU": 0.9038734093395536, "TOVIAZ": 0.8947930475688556, "TOZINAMERAN": 0.8232664725090211, "TRACLEER": 0.5391803549598843, "TRULICITY": 0.6264898456882767, "VAXZEVRIA": 0.82712323918943, "VICTOZA": 1.41104901576429, "VOTRIENT": 0.9573753289126044, "XELJANZ": 0.3678330596166844, "XOLAIR": 0.3268112383668605, "XTANDI": 0.4179967953463404, "ZOSTAVAX": 0.8610390491050592, "null": 0.8779953783744214}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/370.json
index bd6dced3c12..26ffb6c90b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/370.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/370.json
@@ -1 +1 @@
-{"BRIDION": 31.648858202284764, "BUPIVACAINE": 23.08850381165105, "FENTANYL": 17.957182115850124, "MIDAZOLAM": 17.363640920387503, "SUFENTANIL": 65.0873203784674, "null": 8.11981345920038}
\ No newline at end of file
+{"BUPRENORPHINE": 17.26696753349564, "OLANZAPINE": 9.70691018839118, "SUBOXONE": 28.31181249799493, "ZYPREXA": 8.28936972127874, "null": 3.780854107598272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3700.json
index 350f28e56fa..7bd84f074f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3700.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3700.json
@@ -1 +1 @@
-{"SOLIRIS": 96.85133304387536}
\ No newline at end of file
+{"ABACAVIR": 0.0923594714415039, "ABECMA": 102.944575958747, "ABEMACICLIB": 3.1412143460413438, "ABIRATERONE": 19.19293996840077, "ABRAXANE": 5.21830205447912, "ACALABRUTINIB": 55.143023382756525, "ADALIMUMAB": 0.1802403760070338, "ADCETRIS": 3.0142230171170707, "ADCIRCA": 0.6161377607344549, "AFATINIB": 23.84815653129202, "AFINITOR": 2.9404008053310178, "AFLIBERCEPT": 5.819043052466748, "ALECTINIB": 15.624291637905497, "ALEMTUZUMAB": 0.9484115664417992, "ALIMTA": 2.222518193787234, "ALPELISIB": 3.180679690230368, "AMBRISENTAN": 1.3937743530031543, "AMIKACIN": 1.1534394257476366, "AMINOSALICYLIC": 0.5292843550253763, "ANAKINRA": 0.4357582450779739, "APIXABAN": 0.1959691422968203, "ARANESP": 0.2511420547146077, "ARAVA": 0.219729478283624, "ARIPIPRAZOLE": 1.068008173575654, "ARZERRA": 4.333681094365547, "ASPARAGINASE": 0.8983950233273076, "ATEZOLIZUMAB": 15.046580992898104, "AUBAGIO": 0.6144423505206954, "AVAPRITINIB": 15.402339030639132, "AVASTIN": 28.045569615282854, "AVELUMAB": 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0.7731423415940187, "YESCARTA": 15.335334935028651, "YONDELIS": 5.430112799785632, "YTTRIUM90": 66.12009232952163, "ZAVESCA": 11.499081780696724, "ZELBORAF": 9.158677438627237, "ZOLEDRONIC": 4.5333313600465255, "null": 0.3864384484889864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3701.json
index 2d66adec518..183d1ed3406 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3701.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3701.json
@@ -1 +1 @@
-{"null": 2.2450342229325893}
\ No newline at end of file
+{"ABACAVIR": 0.3636580248744526, "ABATACEPT": 0.3262643311547263, "ABILIFY": 2.335310974678314, "ACLASTA": 10.52068280893208, "ADALIMUMAB": 0.4514834164136037, "AIMOVIG": 0.4916537063583266, "ALEMTUZUMAB": 1.620491288975301, "AMIKACIN": 6.960585413412245, "APIXABAN": 0.2678679495597569, "ARAVA": 0.5778193925745565, "ARIPIPRAZOLE": 1.8043250947922505, "ASPARAGINASE": 1.3499787776302286, "AUBAGIO": 0.7608387608035504, "AVAMYS": 2.1360962222784328, "AVASTIN": 0.9023181204398458, "AZACITIDINE": 3.2231194505925878, "AZATHIOPRINE": 4.997869095178835, "BASILIXIMAB": 9.549150639687678, "BENLYSTA": 2.3263480171405644, "BEVACIZUMAB": 2.994150114643769, "BORTEZOMIB": 2.891754458033989, "BRINTELLIX": 1.0020814238410094, "BUDESONIDE": 1.3667704328879686, "BUSILVEX": 14.74881943694129, "BUSULFAN": 2.805448351378909, "CAPECITABINE": 2.976671515626132, "CARMUSTINE": 8.6425599556636, "CELECOXIB": 1.574682091386975, "CELLCEPT": 0.959673933280297, "CHAMPIX": 2.178351501359972, "CICLOSPORIN": 5.809415924523265, "CLADRIBINE": 6.574823311959797, "CLINDAMYCIN": 25.073184236406327, "CLOPIDOGREL": 0.986551926065998, "COMIRNATY": 1.3252983707649562, "COSENTYX": 1.681594028288859, "CYTARABINE": 5.520821180831333, "DABRAFENIB": 2.3186438956629987, "DEXAMETHASONE": 2.57190255111258, "DIFICLIR": 21.825328638329424, "DOCETAXEL": 2.616318439607925, "DOXORUBICIN": 2.5475233043321355, "EFAVIRENZ": 1.4651726309591384, "ELIQUIS": 0.2848147841107381, "ENBREL": 0.5855354785558355, "ENTYVIO": 0.4338958422878615, "ESOMEPRAZOLE": 2.616885450166313, "FASLODEX": 1.2391264815059009, "FIDAXOMICIN": 21.4153122058721, "HEPSERA": 2.2589199340022503, "HERCEPTIN": 1.359706064395278, "HUMIRA": 0.3539830880833002, "HYDROCORTISONE": 3.0577490342394613, "IBRANCE": 0.6785445895101304, "IBUPROFEN": 0.472928161169125, "IMATINIB": 4.054744130744094, "INFLIXIMAB": 2.0283104752341763, "IRINOTECAN": 1.580181989878214, "JAKAVI": 0.7096614969431679, "KEPPRA": 0.1527149184089271, "KESIMPTA": 4.121766049866988, "KYMRIAH": 4.768185422539154, "LACOSAMIDE": 4.323052699964014, "LEMTRADA": 1.531399435459908, "LEVETIRACETAM": 2.780853434363451, "LEVOFLOXACIN": 0.382404200086659, "LYNPARZA": 2.1552986605033952, "LYRICA": 0.5620577470897804, "MABTHERA": 2.5983683547370484, "MERCAPTOPURINE": 5.329007711682954, "METHOTREXATE": 2.1446375083347866, "MODERNA": 1.1298051685351214, "MYCOPHENOLATE": 1.7848412343067326, "NUCALA": 2.8627836538740583, "OLANZAPINE": 1.603457072339348, "OMALIZUMAB": 0.6121687289258243, "PANTOPRAZOLE": 5.855321372942916, "PEGASYS": 1.0463756452476125, "PEGINTERFERON": 2.278641552618645, "PEGINTRON": 0.4491451809810737, "RIBAVIRIN": 0.7732536376634048, "RITUXIMAB": 2.6171485163007087, "ROACTEMRA": 0.4591068135131516, "RUXOLITINIB": 4.717073933498607, "SOLIRIS": 4.047279806272615, "SOMATROPIN": 10.460935280923849, "SPIKEVAX": 0.3431707857060239, "SUTENT": 0.8849763419311306, "SYCREST": 4.334377342903216, "TEMOZOLOMIDE": 13.053283133201347, "TOPOTECAN": 10.205481727110444, "TOZINAMERAN": 6.736205043999007, "TRELEGY": 0.5020283271999932, "VAXZEVRIA": 0.0982852470300605, "VFEND": 3.626196944954191, "VORICONAZOLE": 1.8685986688309528, "XELJANZ": 4.981710010976043, "XOLAIR": 0.3957666370945614, "YESCARTA": 5.695378780197661, "ZYPREXA": 0.2542180497423362, "null": 0.5835035722952342}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3702.json
index bd9381db748..dd566505e8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3702.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3702.json
@@ -1 +1 @@
-{"COVID19": 1.9090345950390977, "MMRVAXPRO": 14.447342841230578, "VAXZEVRIA": 1.165041471816412}
\ No newline at end of file
+{"null": 0.2381016593947709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3703.json
index 12daf887a20..ea8167863be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3703.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3703.json
@@ -1 +1 @@
-{"SUBOXONE": 40.79234403401701, "null": 2.0301784492250383}
\ No newline at end of file
+{"ARAVA": 4.002942031850453, "COMIRNATY": 1.819015968296194, "null": 0.5174654931633078}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3704.json
index 7792ae90f4b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3704.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3704.json
@@ -1 +1 @@
-{"BUDESONIDE": 15.85349694615426, "CICLOSPORIN": 11.411447123407187, "null": 3.586585324006094}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3705.json
index 3f27564b50f..3a01d7f5c4d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3705.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3705.json
@@ -1 +1 @@
-{"AIMOVIG": 1.958897445732572, "BENLYSTA": 1.2820093806333253, "BETMIGA": 1.4746841534527872, "BOTULINUM": 74.1577146490275, "BRINTELLIX": 2.726704514541335, "CHAMPIX": 1.153187331265402, "COMIRNATY": 2.037629200056689, "COVID19": 1.748605903903148, "EBIXA": 3.262171527426476, "ERENUMAB": 4.594867889050179, "EXFORGE": 1.3532582750508224, "FIRDAPSE": 1.6937509172686256, "FORSTEO": 1.6817014942328277, "IRON": 5.230813008292253, "KAFTRIO": 1.023640275479616, "LIXIANA": 1.5208252664582091, "MELATONIN": 1.5898322315146274, "MEPOLIZUMAB": 2.147052489257701, "RASILEZ": 1.5817141336224074, "RELVAR": 1.2071030085848986, "SIFROL": 1.5868259026629108, "SPIKEVAX": 1.477083798780284, "TOZINAMERAN": 2.496672838788029, "VAXZEVRIA": 2.2804921186881777}
\ No newline at end of file
+{"ABILIFY": 137.949182172577, "ARIPIPRAZOLE": 245.0538821239722, "CANNABIDIOL": 46.48321769964711, "CHAMPIX": 2.3321110003189918, "CYMBALTA": 2.0493884580962853, "KEPPRA": 2.1517644384008108, "OLANZAPINE": 5.749555668057515, "ZYPREXA": 2.931223054429402, "null": 0.8489249919208381}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3706.json
index 5638ca04b79..cd57cca0d5f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3706.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3706.json
@@ -1 +1 @@
-{"ABILIFY": 1.07187163366021, "ADEMPAS": 3.407176019874939, "ADVATE": 11.662746173364592, "ANORO": 1.7543050991150089, "AUBAGIO": 2.1150458665514336, "BOSULIF": 1.621257115697406, "BYDUREON": 1.1248072472499075, "BYETTA": 1.2548560810275216, "CARBIDOPA": 5.496764796895023, "CLOPIDOGREL": 1.0827477177711546, "COAPROVEL": 1.453231678220704, "CYMBALTA": 1.9305692267502577, "CYTARABINE": 1.3138509374712095, "ELIQUIS": 5.419359569605819, "EMICIZUMAB": 40.897408721612, "ENTRESTO": 2.1249779247579745, "ESBRIET": 1.4890150724029263, "EVISTA": 2.8086317631680355, "FAMPYRA": 2.184920308143882, "FIRDAPSE": 3.303139302154598, "FORSTEO": 2.017524715744212, "FYCOMPA": 6.676504151030104, "GARDASIL": 5.776231490997012, "HEMLIBRA": 32.61547141284012, "HIZENTRA": 1.9952020747904624, "HUMALOG": 3.5914285189349053, "HYDROCORTISONE": 1.8174407284835985, "IBRANCE": 1.106281413892935, "INLYTA": 1.0372089171205363, "JAKAVI": 1.0480059231124728, "JANUVIA": 1.2732061399191243, "KEPPRA": 3.2505317147597084, "LANTUS": 1.988988682025372, "LATUDA": 2.049495255294012, "LEVEMIR": 1.2529199720203836, "LYRICA": 2.988036728157918, "MENVEO": 5.515812438376587, "MICARDIS": 1.232816616473173, "MIDAZOLAM": 1.1904747472175352, "NAGLAZYME": 4.805716466873002, "OPSUMIT": 2.1011970579048507, "PEGINTRON": 1.254530146136981, "PLAVIX": 2.0672421933858205, "REVATIO": 3.4570171238113585, "RUBRACA": 1.4706571955082617, "SOMATROPIN": 4.360510550601289, "STALEVO": 1.9633483417310411, "SUBOXONE": 2.8684215703256477, "TOVIAZ": 2.3192771840047235, "TOZINAMERAN": 1.2363413173325857, "TRACLEER": 1.170709957948665, "TRELEGY": 1.311020487187759, "TRULICITY": 1.04943386603638, "VELTASSA": 1.9710157027149964, "VIAGRA": 1.6501226123231696, "VIMPAT": 5.443299115673567, "XARELTO": 1.0832614337139328, "XTANDI": 2.023987785892876, "XYREM": 2.781333811644462, "ZYPREXA": 1.518401669381294, "null": 1.543166526924173}
\ No newline at end of file
+{"FORSTEO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3707.json
index 9efd871c21a..1669b0bed86 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3707.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3707.json
@@ -1 +1 @@
-{"COVID19": 4.564915104349509}
\ No newline at end of file
+{"ABATACEPT": 56.28169291299853, "ADALIMUMAB": 66.04760176205484, "AMINOSALICYLIC": 9.009683414896852, "APREMILAST": 221.507324583466, "ARAVA": 2.1452438417989543, "COSENTYX": 3.810563179262849, "ENTYVIO": 2.889439126500664, "RITUXIMAB": 3.150472034718183, "XELJANZ": 0.896373039520305, "null": 0.1075239485539748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3708.json
index 8ea611044fb..37f565f86fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3708.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3708.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 34.14931260645772, "CYMBALTA": 1.920515707802266, "KEPPRA": 4.238065300472702, "null": 1.4229022158250546}
\ No newline at end of file
+{"null": 0.8145643285262828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3709.json
index fa00502af3c..463bf1caf63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3709.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3709.json
@@ -1 +1 @@
-{"ALIGN": 1.01459067212869, "AMBIRIX": 1.1321475768679037, "BAQSIMI": 1.8226057951069232, "BOTULINUM": 2.273232320230348, "CERVARIX": 1.5121472735722528, "COMIRNATY": 2.6377812993112717, "COVID19": 4.419550032644259, "DUKORAL": 1.2815228311200677, "ELASOMERAN": 1.270840806959311, "FLEBOGAMMA": 1.597919496594268, "FLUCELVAX": 1.4339003114883704, "GARDASIL": 1.296305399948788, "JCOVDEN": 1.9721827344674216, "KIOVIG": 1.249139415776328, "LEVITRA": 1.233882718647769, "LIVOGIVA": 1.1461705539667195, "MENVEO": 1.2937452390866482, "NIMENRIX": 2.3428405774809, "NUSINERSEN": 1.186640140798963, "OMNITROPE": 1.1689892119579672, "PRIVIGEN": 1.5159140741356532, "RAPISCAN": 1.0085500412664243, "RYEQO": 1.193409060105556, "SHINGRIX": 1.0978033400089504, "SILGARD": 1.2224013197633226, "SPIKEVAX": 2.5881114100736435, "TERROSA": 1.0301017498124023, "TOZINAMERAN": 1.5189849194349423, "TRUMENBA": 1.742235170155653, "UPTRAVI": 1.1279784791370573, "VAXZEVRIA": 3.4656336201849878}
\ No newline at end of file
+{"ARIPIPRAZOLE": 6.308493833700546, "COMIRNATY": 0.3012635927656742, "INSULIN": 3.61949011579763, "KEPPRA": 1.4106701792304348, "LEVOFLOXACIN": 8.734730625978711, "OLANZAPINE": 2.4862755930455034, "SPIKEVAX": 0.2401643124758577, "VAXZEVRIA": 0.4169092594487428, "VFEND": 73.83885576482369, "VORICONAZOLE": 64.52847963130108, "null": 2.0025157311201185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/371.json
index ad9e3ac66a1..c51bac2f0cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/371.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/371.json
@@ -1 +1 @@
-{"FENTANYL": 6.453731344829355, "MIDAZOLAM": 638.7951811642432, "SUFENTANIL": 893.9317810214162}
\ No newline at end of file
+{"CELLCEPT": 71.6212638934499, "null": 2.5442359161660035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3710.json
index 9fe339f1f00..dc3368f07ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3710.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3710.json
@@ -1 +1 @@
-{"null": 1.119506281660774}
\ No newline at end of file
+{"ABACAVIR": 0.1993536468603492, "ABILIFY": 1.5523786070059855, "ACE": 14.069035486146465, "AERIUS": 1.811499603136464, "AFINITOR": 0.4783869807476157, "AIMOVIG": 0.510065118566721, "ALIMTA": 0.2738739681613164, "ANORO": 0.4939055419219221, "APIDRA": 0.6899642109334242, "APIXABAN": 0.1524673651701582, "APROVEL": 1.220707427952813, "ARANESP": 0.1646696686132497, "ARAVA": 0.0284007799700385, "ARIPIPRAZOLE": 1.1427405863016324, "ATRIPLA": 0.0303805865827049, "AUBAGIO": 0.1901775770125232, "AVAMYS": 0.3349773643868964, "AVANDIA": 0.3587333097542427, "AVASTIN": 0.4534704040740483, "AZATHIOPRINE": 0.3875398039359072, "BENLYSTA": 0.5444451893298464, "BIKTARVY": 0.7971222985063534, "BORTEZOMIB": 1.856590840553654, "BRAFTOVI": 0.5169259109205653, "BRINTELLIX": 0.8326192562459251, "BUDESONIDE": 0.3273924010046986, "BUPRENORPHINE": 2.1791082524449967, "BYDUREON": 0.7262574102191347, "CABOMETYX": 0.4995535923506687, "CAELYX": 0.9692298760885928, "CAPECITABINE": 0.417229059033462, "CELECOXIB": 0.8767877676664614, "CELLCEPT": 0.3235199037714352, "CHAMPIX": 2.887547616825142, "CICLOSPORIN": 0.7496956164199688, "CIRCADIN": 3.2616248585858125, "CLOPIDOGREL": 0.2999201444638921, "COAPROVEL": 1.4206980556957525, "COLESEVELAM": 151.6179261085339, "COMIRNATY": 0.3796291660824482, "COMTAN": 5.110955595625864, "COSENTYX": 0.2148180821647917, "COTELLIC": 1.0919003440803552, "CYMBALTA": 1.7348157222216702, "CYTARABINE": 0.627219619626719, "DEXAMETHASONE": 0.7919188395334238, "DULOXETINE": 1.2916930432141258, "EBIXA": 3.7591287089948553, "ELIQUIS": 0.1847030657977183, "EMTRICITABINE": 1.115224241740114, "ENOXAPARIN": 0.6308893962891796, "ENTRESTO": 0.6601968306353658, "EPIVIR": 2.6282082386729706, "ESBRIET": 0.3047641810083244, "ESOMEPRAZOLE": 1.3149518713921344, "EXFORGE": 0.4585005260973809, "EXJADE": 0.1865634855143215, "EXVIERA": 1.9390329349265896, "EYLEA": 0.4165853473129555, "FASLODEX": 0.2355687174960437, "FENTANYL": 1.2960102412095271, "FORSTEO": 0.7545711576371356, "FYCOMPA": 1.5083841067668693, "GARDASIL": 1.0663852032919685, "HARVONI": 0.6046820029735503, "HUMALOG": 1.0330439475388933, "HUMIRA": 0.2496899311363516, "HYDROCORTISONE": 1.5961681556341518, "IBRANCE": 0.1962523108401417, "IBUPROFEN": 1.0250147211587883, "INCIVO": 0.3906091878496923, "INLYTA": 0.8817719120940628, "INSULIN": 0.5893508337584498, "IRBESARTAN": 0.6516302873668761, "IRINOTECAN": 0.7170212096190677, "JAKAVI": 0.4879587968848011, "JANUMET": 0.427872556541811, "JANUVIA": 0.292131375987369, "JARDIANCE": 0.5261421110410219, "KALETRA": 0.566305048376929, "KEPPRA": 2.038017173595857, "KEYTRUDA": 0.3452170777024426, "KYMRIAH": 3.627609349416739, "LACOSAMIDE": 1.1861634848389573, "LANTUS": 1.0441014798809585, "LATUDA": 0.6861446208056311, "LEVETIRACETAM": 1.6789637625293847, "LEVOFLOXACIN": 1.3495312773157755, "LYRICA": 3.1251853777569183, "MEKINIST": 0.9206426559903716, "MELATONIN": 3.251595783394677, "MENVEO": 0.9396974070907378, "METHOTREXATE": 0.1580865928125913, "MICARDIS": 1.0386202067566537, "MIDAZOLAM": 1.7809506298677251, "MIRCERA": 1.243854910733728, "MODERNA": 0.1453938945818911, "NEULASTA": 0.5666214570482, "NEXAVAR": 1.2824180279429942, "NIMENRIX": 0.3743909809258373, "NOT": 1.104545452128398, "NOVORAPID": 0.4030286147056592, "NOXAFIL": 1.6283345263825275, "NUCALA": 0.2249870567678971, "OCRELIZUMAB": 0.3566924232518641, "OLANZAPINE": 2.980218637151792, "OLYSIO": 0.7846313275378407, "OPDIVO": 0.330781366280702, "OPSUMIT": 0.363841965967165, "OXYBUTYNIN": 2.5741361729414067, "PANTOPRAZOLE": 1.2857524305031496, "PEGASYS": 0.9156412669314948, "PEGINTERFERON": 0.4188408625586982, "PEGINTRON": 1.2534763213385367, "PLAVIX": 0.5827328562439427, "PREGABALIN": 1.411552137937504, "PROTELOS": 2.5225128899865514, "RANEXA": 2.815224351009764, "RASILEZ": 0.7483396285809149, "REBETOL": 0.996076195319242, "REVATIO": 0.4167966577011316, "RISPERIDONE": 1.5529326536496242, "RIVAROXABAN": 2.7166602035279754, "SHINGRIX": 0.6448738146610913, "SIFROL": 1.623965128971446, "SILDENAFIL": 0.753223443523739, "SIMPONI": 0.1946056486980537, "SOLIRIS": 0.2967247828180789, "SPIKEVAX": 0.522417137950652, "STALEVO": 3.98730445254888, "STELARA": 0.5317996935614895, "STIVARGA": 1.0198497135178766, "SUBOXONE": 1.0355704848712295, "SUTENT": 0.6317886835937249, "SYCREST": 6.522114262989159, "TAMIFLU": 3.3320223622380887, "TASIGNA": 0.4744889775475285, "TELMISARTAN": 1.2078166119029934, "THALIDOMIDE": 2.00625300028967, "TOVIAZ": 0.646409960400945, "TOZINAMERAN": 1.1483831275929612, "TRACLEER": 0.252676914826863, "TWINRIX": 0.743477016619082, "ULTIBRO": 10.887818752596278, "VALDOXAN": 7.018722659935164, "VAXZEVRIA": 0.6768277090329327, "VFEND": 2.828792059725842, "VIAGRA": 0.6216111190183714, "VIMPAT": 1.8038251207403773, "VORICONAZOLE": 1.3404086731584977, "VOTRIENT": 0.7008613291047606, "XARELTO": 0.7906509652950021, "XELJANZ": 0.2228138660592677, "XELODA": 0.8511607781005771, "XOLAIR": 0.2940287603371211, "XTANDI": 1.29113270158352, "XYREM": 1.0989686587207872, "YESCARTA": 4.217527845458372, "ZOSTAVAX": 0.2018393871213542, "ZYPADHERA": 29.82390288543815, "ZYPREXA": 2.227140069878215, "null": 2.115501183140736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3711.json
index 77b44d8eba1..a618c5d196d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3711.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3711.json
@@ -1 +1 @@
-{"null": 1.1569185385030298}
\ No newline at end of file
+{"ALEMTUZUMAB": 94.17811566088496, "CICLOSPORIN": 13.414547105851891, "RITUXIMAB": 76.94110551115148, "TOZINAMERAN": 9.130387982057467, "VAXZEVRIA": 0.5362511199050228, "null": 0.451230337311873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3712.json
index b524d534b19..55394287959 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3712.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3712.json
@@ -1 +1 @@
-{"null": 1.0963270671969376}
\ No newline at end of file
+{"ASPARAGINASE": 490.1458222658583, "CICLOSPORIN": 12.388230519521873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3713.json
index a20d050cfd6..6e9d8770137 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3713.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3713.json
@@ -1 +1 @@
-{"OPSUMIT": 116.41666058635778, "TRACLEER": 153.6498255998542}
\ No newline at end of file
+{"CELLCEPT": 22.49559140577251, "CICLOSPORIN": 16.58536585413846, "DEXAMETHASONE": 22.29877315067439, "null": 0.2805590301193854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3714.json
index d872febe280..84892f27d15 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3714.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3714.json
@@ -1 +1 @@
-{"null": 2.6974128087585774}
\ No newline at end of file
+{"GANCICLOVIR": 406.71840639623866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3715.json
index 27e657a3dd2..6f67beeb341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3715.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3715.json
@@ -1 +1 @@
-{"ALISKIREN": 9.782031862423205, "CELLCEPT": 1.6899082133776382, "COMBIVIR": 5.062314841351838, "IBUPROFEN": 2.90783747424673, "KEPPRA": 1.9101411849451384, "NORVIR": 22.051945591775198, "STELARA": 1.1448297296328391, "SUBOXONE": 3.2647461915389453, "SYNAGIS": 14.403515377699994, "TRACLEER": 2.1924865879802984, "ZYPREXA": 1.0009403870644469, "null": 6.039561546973297}
\ No newline at end of file
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3716.json
index 690ce7f3c82..91a65f81d07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3716.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3716.json
@@ -1 +1 @@
-{"ENTRESTO": 30.516256251498195}
\ No newline at end of file
+{"AFINITOR": 0.6252715592506088, "ALIMTA": 4.687109409484428, "APREMILAST": 3.682433240215802, "ARAVA": 0.1576193498461349, "ASPARAGINASE": 4.76279941265032, "AVASTIN": 8.771080770301095, "AZATHIOPRINE": 2.022910993978622, "BEVACIZUMAB": 1.876845546186112, "BORTEZOMIB": 2.0245072744810626, "BRIDION": 2.062691717823951, "BUSULFAN": 3.417739983390168, "CANCIDAS": 6.955663025089515, "CAPECITABINE": 0.956073807084361, "CASPOFUNGIN": 6.919115430306952, "CELECOXIB": 1.8357720906699315, "CELLCEPT": 3.8655476097378463, "CICLOSPORIN": 3.131379828095676, "CLOPIDOGREL": 1.0478430302217814, "COMBIVIR": 1.6264751173266492, "COMIRNATY": 0.0863237369569661, "CRIXIVAN": 2.632562002279617, "CUBICIN": 5.031266931004899, "CYMBALTA": 0.130610105724831, "CYTARABINE": 3.660186505386039, "DAPTOMYCIN": 8.684994398395828, "DARZALEX": 1.511778995241228, "DEXAMETHASONE": 1.9497113829047532, "DOCETAXEL": 1.589893955659028, "ELIQUIS": 0.8942047903208373, "EPIVIR": 2.0704977563861364, "ERBITUX": 5.349117565989818, "EXJADE": 1.026553311910772, "FENTANYL": 1.8496622250511463, "FORXIGA": 0.5897587513370942, "GLIVEC": 3.967847195584105, "HALAVEN": 5.112163176540674, "HARVONI": 1.8557647527754035, "HUMAN": 2.739386876042976, "HYDROCORTISONE": 1.5740292400920828, "IBRANCE": 0.3446016358064878, "IBUPROFEN": 1.5317311276060646, "INCIVO": 1.0135283937334147, "INTRONA": 3.195812437602445, "IPILIMUMAB": 1.2109411722840593, "IRESSA": 5.397030623116333, "IRINOTECAN": 1.8606248915996184, "JAKAVI": 1.1803657873753215, "JANUVIA": 1.121533109571845, "JEVTANA": 16.614566679473494, "KALETRA": 0.947365948736376, "KEPPRA": 0.2523483737159228, "KEYTRUDA": 3.681410023653378, "KYMRIAH": 4.148602777615936, "LAMIVUDINE": 2.933873924414, "LENVIMA": 2.846569099635216, "LEVETIRACETAM": 0.6948462394725594, "LEVOFLOXACIN": 2.343479865828165, "MANNITOL": 8.881459736169768, "MEKINIST": 2.3922626869719816, "METHOTREXATE": 2.1565805228021486, "MIDAZOLAM": 3.650591722140139, "NEXAVAR": 3.661003157919884, "NIVOLUMAB": 6.398233506509516, "NOVOSEVEN": 46.49702813315186, "NOXAFIL": 3.526934410348404, "NPLATE": 1.500913958095063, "OCTREOTIDE": 19.71523571605949, "ONCASPAR": 3.1381527471154307, "OPDIVO": 6.33840348610658, "PACLITAXEL": 3.0054411477035305, "PANTOPRAZOLE": 1.7657257094998198, "PEGASYS": 1.7795532481426477, "PEGINTRON": 2.8599875684713667, "PEMBROLIZUMAB": 0.8856635185756171, "PLAVIX": 1.1388426458331031, "REMDESIVIR": 8.658614844302221, "REMICADE": 1.8876259371661075, "RITUXIMAB": 0.6167386666748051, "ROACTEMRA": 1.9743500525167168, "SIMPONI": 0.5051472367158084, "SOLIRIS": 1.7195543656554213, "SOVALDI": 2.2543983797041407, "SPIKEVAX": 0.0576983063410589, "STELARA": 0.220556876680685, "STIVARGA": 8.093017908698611, "SUTENT": 2.1243016498100364, "TAGRISSO": 1.197416806338872, "TAMIFLU": 3.397094585647697, "TEMODAL": 4.194103887785389, "TISAGENLECLEUCEL": 38.38684237003344, "TOZINAMERAN": 0.0659222800304815, "TRISENOX": 12.92259288965895, "VAXZEVRIA": 0.1192059510600138, "VEKLURY": 6.684090588785524, "VFEND": 2.297007224643392, "VOTRIENT": 1.0369884167498955, "XELODA": 4.980523480836592, "XOFIGO": 3.431733579833558, "XTANDI": 0.7434893327175509, "YESCARTA": 3.3469378820965554, "ZYPREXA": 0.96000172422518, "null": 1.8631767868424067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3717.json
index 9f5b7cb86f6..e7d5d52adc4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3717.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3717.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 8.198624856700048, "ENTRESTO": 56.69108818540332, "SPIRONOLACTONE": 91.6620794935685, "TAGRISSO": 28.31332695155776}
\ No newline at end of file
+{"ASPARAGINASE": 79.74362905613967, "BUSULFAN": 53.96634974557225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3718.json
index 94f28178076..98261161040 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3718.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3718.json
@@ -1 +1 @@
-{"COVID19": 28.741196662589243, "SPIKEVAX": 2.476791207621503, "TOZINAMERAN": 2.2292424886613262}
\ No newline at end of file
+{"ABACAVIR": 69.60096594591275, "AMIKACIN": 179.9172786839936, "null": 0.2640964166145383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3719.json
index c68ce8ab4c4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3719.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3719.json
@@ -1 +1 @@
-{"AIMOVIG": 2.8712571655277626, "COMIRNATY": 1.1513147884463135, "DOXORUBICIN": 6.062422331254474, "ELIQUIS": 1.545705940410374, "ENTRESTO": 4.122690429358669, "FILGRASTIM": 11.977554611581343, "IBUPROFEN": 1.9082529085122968, "LEMTRADA": 3.132716376214324, "LEVOFLOXACIN": 1.679372267735377, "TOZINAMERAN": 4.583729138405138}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/372.json
index a4e332073cb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/372.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/372.json
@@ -1 +1 @@
-{"ABATACEPT": 3.5072282205427, "ADALIMUMAB": 1.2707831639419436, "ARAVA": 4.494408690296324, "BUSULFAN": 4.576783656522131, "CIMZIA": 4.856043592079399, "COSENTYX": 2.2380244819653226, "ENTYVIO": 46.87329115799282, "FORXIGA": 7.40268720806141, "HUMIRA": 4.236894888333481, "INCIVO": 11.879287286122594, "JARDIANCE": 11.006052867288464, "NEXAVAR": 3.717694595348619, "PEGASYS": 1.526958314169339, "REMICADE": 17.675508223543115, "SIMPONI": 4.164419390009536, "STELARA": 17.37110528243891, "STIVARGA": 4.952402543059005, "SUTENT": 4.059823448383918, "XELJANZ": 1.588232360007375}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3720.json
index d3f6b7a8e70..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3720.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3720.json
@@ -1 +1 @@
-{"ACLASTA": 7.617924085514173, "AFINITOR": 1.231401659850134, "ALEMTUZUMAB": 2.591183967688109, "ANAKINRA": 2.213430083068383, "BOSULIF": 1.1417310859677614, "BRIDION": 4.840274743219678, "BRILIQUE": 2.0320515213203643, "BUPIVACAINE": 2.0553981491596027, "CAPECITABINE": 1.0490986749592537, "CELECOXIB": 1.2995293233833385, "CLOPIDOGREL": 1.1834605222817365, "CORTICOSTEROIDS": 10.77143943380814, "DEXAMETHASONE": 1.2641493224357816, "DEXMEDETOMIDINE": 5.665609169208732, "DULOXETINE": 1.3919152940308808, "ELIQUIS": 1.0905611697981863, "ENTRESTO": 4.860297003144631, "ESBRIET": 1.0431517394166698, "ESOMEPRAZOLE": 2.1067836539002034, "EXFORGE": 2.50237276481534, "FENTANYL": 3.0916025010631323, "HUMAN": 1.5531305656631014, "ILARIS": 41.69282799220811, "INFLECTRA": 10.545648607614371, "INFLIXIMAB": 2.120600863498509, "IRBESARTAN": 1.6296011925425915, "IRON": 3.366443240168534, "LEFLUNOMIDE": 2.087218048957104, "LEMTRADA": 3.256731081357765, "LYRICA": 1.576214329238767, "MENVEO": 3.1463137600313003, "METHOTREXATE": 3.823242509053709, "MICARDIS": 2.7864702642518, "MIDAZOLAM": 4.695325103821082, "MULTAQ": 10.769817329415172, "OCTREOTIDE": 11.257876641843296, "OLANZAPINE": 1.009294326986421, "OMALIZUMAB": 2.474138362896178, "OPSUMIT": 1.161493190037802, "ORENCIA": 7.639315555863181, "PANTOPRAZOLE": 4.518689831524696, "PRIVIGEN": 1.166569808267551, "PROPRANOLOL": 12.29596888045791, "RANOLAZINE": 5.70689113614341, "RAPISCAN": 22.20754325626869, "RASILEZ": 2.701663508521147, "REGADENOSON": 69.67538769661037, "REMICADE": 1.566281079366589, "REVATIO": 1.1801697054737226, "RITUXIMAB": 7.341668912577151, "SILDENAFIL": 1.9916090902923431, "SOMAVERT": 15.84040714212818, "SPINRAZA": 1.3423464581222238, "SUFENTANIL": 1.8949720608422933, "TELMISARTAN": 5.281758681616276, "TIKOSYN": 14.197114362627648, "TOZINAMERAN": 1.1349997995441994, "VALSARTAN": 7.104071597069544, "VIAGRA": 1.6082996327086032, "XALKORI": 3.912367495704781, "XARELTO": 1.2122200835529051, "XOLAIR": 1.5148030915810298, "XYREM": 2.018743809974245, "null": 1.961426498114599}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3721.json
index 4bc1d78d8e4..3ef5fbbe777 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3721.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3721.json
@@ -1 +1 @@
-{"ADCIRCA": 1.4447247211604015, "ADEMPAS": 1.3957717437550352, "AERIUS": 1.014681809420109, "AGALSIDASE": 9.13627834487562, "APIXABAN": 3.370085165709133, "APROVEL": 1.353047407386458, "BELIMUMAB": 1.1290789117598683, "BETMIGA": 2.699753889760992, "BRIDION": 1.5990210804575076, "BUPIVACAINE": 1.4834082094827297, "COMIRNATY": 1.3245433270072604, "COVID19": 1.481548698123897, "DALIRESP": 4.839791328308693, "DASATINIB": 2.3638012108761903, "DUAKLIR": 9.99646814652509, "DULAGLUTIDE": 1.2466249679149006, "EMGALITY": 25.67937806453716, "ENTRESTO": 1.2030408297741428, "ESBRIET": 1.645006660880702, "EVISTA": 1.0817107637050822, "EXFORGE": 1.4044521175823317, "FENTANYL": 1.0912755229817304, "FLEBOGAMMA": 3.4979186956850405, "FORSTEO": 1.954046586657236, "GARDASIL": 1.0553947216760886, "HIZENTRA": 1.0853235797897802, "HYDROCHLOROTHIAZIDE": 1.7884368465642506, "IVABRADINE": 1.6853518791643347, "KETOCONAZOLE": 2.483794224687885, "KIOVIG": 1.555572618940503, "LEMTRADA": 2.1619200581816465, "MANNITOL": 1.5154423864483442, "MELATONIN": 1.270157675336263, "MICARDIS": 1.0096886955265565, "MIRCERA": 1.82975604682863, "MULTAQ": 3.281542336909132, "NAGLAZYME": 2.526161159656514, "NALOXONE": 5.450495230275104, "NEULASTA": 1.121335210348113, "NUCALA": 1.110365745148112, "OCRELIZUMAB": 1.2604386967914485, "OMALIZUMAB": 3.556100551072816, "OPSUMIT": 1.8607594507255267, "ORENCIA": 1.6979167644140636, "PERJETA": 2.0255045571431425, "PRIVIGEN": 2.19595753276031, "PROPRANOLOL": 1.5315330991677107, "RAPISCAN": 4.62292254968632, "RASILEZ": 1.1910947840187849, "RELVAR": 1.415905847911873, "REVATIO": 1.0946542715781655, "RITUXIMAB": 2.1052827178991427, "RYBELSUS": 1.4110437371084237, "SAXENDA": 2.044610068856188, "SILDENAFIL": 1.68819892689567, "SPIKEVAX": 1.3560108076256088, "TIKOSYN": 6.239990256040112, "TOZINAMERAN": 2.596481050409661, "TRELEGY": 1.3370146863166132, "TRULICITY": 1.450405139407241, "VALSARTAN": 1.91268443871636, "VAXZEVRIA": 1.3980336265848623, "VIAGRA": 1.5170764971620023, "VICTOZA": 1.476581810498046, "XOLAIR": 2.371493000048711, "XYREM": 1.512969960296317, "ZEJULA": 4.688671924695227, "ZYPADHERA": 5.069417699783813, "null": 1.055248292543146}
\ No newline at end of file
+{"BUSULFAN": 701.3377963392838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3722.json
index 1c57d6799d3..378fa29ccf2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3722.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3722.json
@@ -1 +1 @@
-{"AERIUS": 1.847095035645304, "AVANDAMET": 5.271241572513962, "AVANDIA": 6.273238005579436, "BETMIGA": 3.0533519580028323, "CLOPIDOGREL": 1.198754109534609, "COMIRNATY": 1.2946445233338422, "ELIQUIS": 1.6651288106326292, "ENTRESTO": 3.0873467514235187, "ESBRIET": 1.754381571443284, "ESOMEPRAZOLE": 1.336541961179341, "EXFORGE": 2.249159403687182, "FORSTEO": 2.703183201535672, "FYCOMPA": 3.795845124338, "GARDASIL": 1.127679622073214, "INFLIXIMAB": 2.335261497722776, "LATUDA": 1.1223991734392065, "LEMTRADA": 2.82218354066066, "MEPOLIZUMAB": 1.663759778382102, "MULTAQ": 6.985750944358415, "PANTOPRAZOLE": 1.2004732604638786, "RITUXIMAB": 1.954468604860616, "SPIKEVAX": 1.3400547921207957, "TOVIAZ": 1.2168158400499829, "TOZINAMERAN": 2.479085418341368, "TRELEGY": 1.219694322853072, "VIAGRA": 1.5684696600990793, "XOLAIR": 1.6477811992584128, "null": 1.2180710387561586}
\ No newline at end of file
+{"ADALIMUMAB": 2.220028485748865, "ALEMTUZUMAB": 21.10524424180873, "AZATHIOPRINE": 8.432079657872004, "CELLCEPT": 12.229320083902776, "CICLOSPORIN": 11.259051905486666, "CIMZIA": 6.94468028658797, "DEXAMETHASONE": 7.833025007002868, "EFAVIRENZ": 31.452751516611123, "INFLIXIMAB": 55.729912374370784, "JAKAVI": 15.505871196714654, "LAMIVUDINE": 22.91546804222777, "LEVOFLOXACIN": 11.561574776586005, "METHOTREXATE": 4.362622085856881, "MYCOPHENOLATE": 16.672248245333595, "REMICADE": 39.76308857374054, "SIMPONI": 16.75209938013815, "null": 0.4191626907222223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3723.json
index e10fb8a2120..5b66ebfb9c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3723.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3723.json
@@ -1 +1 @@
-{"COMIRNATY": 2.6759737890019}
\ No newline at end of file
+{"ZOSTAVAX": 99.53534274195084, "null": 0.6745724308500136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3724.json
index 17906fb7822..6172c9b0caf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3724.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3724.json
@@ -1 +1 @@
-{"COMIRNATY": 4.366177200445366}
\ No newline at end of file
+{"null": 0.6040044386620115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3725.json
index fe29c517b53..14d536de1b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3725.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3725.json
@@ -1 +1 @@
-{"INSULIN": 509.0377309557073, "MEPOLIZUMAB": 95.0641364361324, "NUCALA": 38.88681779653847}
\ No newline at end of file
+{"BREXPIPRAZOLE": 461.80251896243504, "BRINTELLIX": 5.055675260022924, "CHAMPIX": 10.39283276986558, "COMIRNATY": 0.4547246092613041, "CYMBALTA": 2.560283196404664, "DULOXETINE": 7.75648710298764, "GARDASIL": 1.436840644038732, "PEGASYS": 0.786116707651444, "SPIKEVAX": 0.5274081401406635, "TOZINAMERAN": 1.085228140714926, "VAXZEVRIA": 0.6089802377321105, "null": 2.3714362043579413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3726.json
index d1f0da11851..3d148224636 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3726.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3726.json
@@ -1 +1 @@
-{"AVANDIA": 5.662628944136256, "CLOPIDOGREL": 6.198842025354285, "null": 2.272948378406922}
\ No newline at end of file
+{"null": 1.2065437336255025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3727.json
index 4449a14eb87..852057b6f64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3727.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3727.json
@@ -1 +1 @@
-{"LANTUS": 5.983111762565416, "OPSUMIT": 15.5823138595535, "RAPAMUNE": 109.08693549545588, "TRACLEER": 44.40121679275831}
\ No newline at end of file
+{"CHAMPIX": 5.028818683504162, "COMIRNATY": 0.2418384425553883, "DULOXETINE": 53.934306565072106, "GARDASIL": 9.51126433642105, "null": 2.71749404921451}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3728.json
index e0ac9c94efa..240995c231f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3728.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3728.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 29.68019956029113, "CELLCEPT": 23.19021462318545, "CICLOSPORIN": 112.14219591799444, "MYCOPHENOLATE": 378.3491857867693, "RAPAMUNE": 73.29288153381675}
\ No newline at end of file
+{"null": 1.5291260004714078}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3729.json
index fd696880369..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3729.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3729.json
@@ -1 +1 @@
-{"null": 1.951361765036119}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/373.json
index b0fffe5bc00..09d6d9973a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/373.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/373.json
@@ -1 +1 @@
-{"APTIVUS": 952.249070345796, "COMBIVIR": 36.07291863631076, "null": 2.899146497746764}
\ No newline at end of file
+{"COMIRNATY": 0.3805063946232496, "null": 1.237053042652953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3730.json
index 1abc46e4d23..666669302b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3730.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3730.json
@@ -1 +1 @@
-{"AVANDIA": 7.480437648802755, "CIMZIA": 1.8133901922436049, "ELIQUIS": 4.297966259728445, "ESBRIET": 8.613462482769634, "IBUPROFEN": 7.847442260438244, "null": 1.648476207830205}
\ No newline at end of file
+{"KAFTRIO": 742.3862272597287, "ORKAMBI": 172.42963801666235, "null": 0.6339250795337608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3731.json
index f3656de88f0..c09014d565d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3731.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3731.json
@@ -1 +1 @@
-{"JARDIANCE": 20.005793438378188}
\ No newline at end of file
+{"ARIPIPRAZOLE": 26.59048887126271, "BUDESONIDE": 7.606981064112952, "COMIRNATY": 0.4013161825575546, "MELATONIN": 63.73754424672382, "VAXZEVRIA": 0.2158658969845804, "null": 1.6718321352928431}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3732.json
index 8f886011977..939bb644fdb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3732.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3732.json
@@ -1 +1 @@
-{"AVANDIA": 8.088474615620378, "ELIQUIS": 7.882346610854357, "LANTUS": 8.501457862876975, "SIMPONI": 9.263428047470663, "TRELEGY": 14.043620342282749, "null": 1.0175543003549965}
\ No newline at end of file
+{"null": 3.372965542111224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3733.json
index de94f4485e7..8220888555a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3733.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3733.json
@@ -1 +1 @@
-{"null": 1.388232084887758}
\ No newline at end of file
+{"ABACAVIR": 0.1695562929628895, "ABILIFY": 1.1388884185918724, "AERIUS": 0.8730332468456017, "AFINITOR": 0.1025172632653527, "AIMOVIG": 2.7433870361872024, "ALEMTUZUMAB": 0.654153229360466, "APIDRA": 0.1481902622838348, "APIXABAN": 4.668192075518651, "ARIPIPRAZOLE": 1.3745357547896515, "ATRIPLA": 0.1076387218723341, "AUBAGIO": 1.1009499174467627, "AVAMYS": 0.2211542345589509, "AVANDIA": 0.0680521295316881, "AZILECT": 5.900616285031044, "BENLYSTA": 0.4452235900506311, "BETMIGA": 0.5153959611585238, "BIKTARVY": 0.6068780030810083, "BOTULINUM": 1.4204614810649188, "BRILIQUE": 0.5149046694068881, "BRINTELLIX": 1.6077145614235728, "BRIVIACT": 2.0470913145914893, "BUPIVACAINE": 0.4633853039616736, "BUPRENORPHINE": 0.9990245531503824, "BYDUREON": 0.3600145325038309, "CARBIDOPA": 1.4196607056218646, "CELECOXIB": 0.4216933696726795, "CELLCEPT": 0.1796627541294886, "CHAMPIX": 4.1690783089417485, "CICLOSPORIN": 0.1266726722473824, "CIMZIA": 0.0629706371697124, "CIRCADIN": 2.272031838453262, "CLOPIDOGREL": 0.076608395189271, "COAPROVEL": 1.0679168633442362, "COMBIVIR": 0.3069678685770876, "COMIRNATY": 2.043077492710574, "COSENTYX": 0.1035326765728516, "CYMBALTA": 2.70044452587039, "DAKLINZA": 2.031793699430957, "DAPAGLIFLOZIN": 2.8716951937684185, "DESLORATADINE": 2.0283881500139285, "DEXAMETHASONE": 0.2617011718368429, "DULOXETINE": 3.5702727080684618, "EBIXA": 1.9167458738968224, "ELIQUIS": 0.2709463773849593, "ELLAONE": 2.3586285730297303, "ENBREL": 0.1278724588043041, "ENTYVIO": 0.5874882303847223, "EXFORGE": 0.2732606713009414, "FAMPYRA": 0.4566306522810376, "FENTANYL": 0.6539983275249591, "FORSTEO": 0.1240096769425916, "FORXIGA": 0.2468733260747075, "FYCOMPA": 2.109607166475475, "GARDASIL": 4.567871360238483, "HARVONI": 0.2647502584720483, "HIZENTRA": 0.2024270924615467, "HUMALOG": 0.2133689968745094, "HUMIRA": 0.178292566323991, "HYDROCORTISONE": 0.4944638635968016, "IBRANCE": 0.2370090129609365, "IBUPROFEN": 0.5929519437636209, "INCIVO": 0.3169197776434282, "INFANRIX": 0.7790238106667761, "INLYTA": 0.2021676069238495, "INTRONA": 0.8931663337329372, "JAKAVI": 0.5380714235949313, "JANUMET": 0.1638182930983708, "JANUVIA": 0.1340626190651087, "JARDIANCE": 0.4529764229659591, "JCOVDEN": 2.6103857208255303, "KAFTRIO": 3.034657055474697, "KALETRA": 0.1945020149398062, "KEPPRA": 2.735240925951926, "KEYTRUDA": 0.0794282991804749, "KYMRIAH": 0.3911678967589387, "LACOSAMIDE": 0.8107197731841751, "LANTUS": 0.2680794573619309, "LATUDA": 1.4011429115916674, "LEMTRADA": 0.5943034163327271, "LEVEMIR": 0.1649164839201412, "LEVETIRACETAM": 1.8848294564732104, "LEVOFLOXACIN": 0.4528066124144527, "LYRICA": 2.156608046559099, "LYSODREN": 5.628209468934589, "MELATONIN": 1.264150230266523, "MEMANTINE": 1.5051862796408408, "METHOTREXATE": 0.2614058028045739, "MICARDIS": 0.4362200670531034, "MIDAZOLAM": 0.3747399354528091, "MIMPARA": 0.8017150849820814, "MMRVAXPRO": 0.247323042627947, "MODERNA": 0.3513779319030363, "NEXAVAR": 0.0603981134538987, "NIMENRIX": 0.2496473542743752, "NORVIR": 0.8668871706099773, "OCRELIZUMAB": 0.8620855792307615, "OFEV": 0.2437143531803292, "OLANZAPINE": 1.3636156885768531, "OXYBUTYNIN": 1.312554116687139, "PANTOPRAZOLE": 0.7661058695772953, "PEGASYS": 1.1637188775214862, "PEGINTERFERON": 1.0643472377204766, "PEGINTRON": 1.6882435117701224, "PLAVIX": 0.2147347464492055, "PLEGRIDY": 0.5115495736077383, "PREGABALIN": 2.509061463998855, "RAPAMUNE": 0.5094041377556661, "REBETOL": 0.7520530209191787, "RIBAVIRIN": 0.7045888778018026, "RINVOQ": 0.3666989622022001, "RISPERIDONE": 1.4407142373962611, "RITUXIMAB": 0.2819181389909482, "ROACTEMRA": 0.1375650894474959, "SERTRALINE": 5.686928432736939, "SHINGRIX": 0.2715990361450261, "SIFROL": 1.4150218450043703, "SIMPONI": 0.0981006861845888, "SOVALDI": 0.6300532806434973, "SPIKEVAX": 1.3336469175717856, "SPRYCEL": 0.1612519182281317, "STELARA": 0.3329340399733059, "STRIBILD": 0.0947267227699137, "SUBOXONE": 0.973205784291796, "SUTENT": 0.1183299176959319, "TAMIFLU": 0.3936347391677026, "TASIGNA": 0.2443912188573783, "TIVICAY": 1.6902516180691265, "TOZINAMERAN": 1.056157813953186, "TRULICITY": 0.2517246726001557, "TRUVADA": 0.0435506105682676, "TWINRIX": 2.025098108605542, "VAXZEVRIA": 1.0351060849357028, "VFEND": 0.4444067595141334, "VIAGRA": 0.2432866002708067, "VICTOZA": 0.2115616010684158, "VIMPAT": 1.7417799273575223, "VOTRIENT": 0.0992103573608629, "XARELTO": 0.3550762351886049, "XELJANZ": 0.0792362759213824, "XOLAIR": 0.2043435905946212, "XTANDI": 0.6321840955010936, "XYREM": 1.6076043728099612, "YESCARTA": 0.4125814303398944, "ZOSTAVAX": 0.2138255524069769, "ZYPADHERA": 3.193905399840759, "ZYPREXA": 1.2391383490180627, "null": 1.0989356856498107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3734.json
index 5819b3886c6..13e2ba92597 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3734.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3734.json
@@ -1 +1 @@
-{"null": 1.1761011494515332}
\ No newline at end of file
+{"BRINTELLIX": 11.356695192269145, "COMIRNATY": 0.1373969302382688, "VIAGRA": 22.110168688848745, "null": 3.8200877251163714}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3735.json
index 8f9e3be97a7..f82108769fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3735.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3735.json
@@ -1 +1 @@
-{"FORXIGA": 24.154608449695}
\ No newline at end of file
+{"ABILIFY": 203.2598417383264, "ARIPIPRAZOLE": 18.877819638737293, "BORTEZOMIB": 32.96847395438122, "OLANZAPINE": 4.399453160462779, "null": 1.6465749902354152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3736.json
index c2b28d18130..66c2f2478c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3736.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3736.json
@@ -1 +1 @@
-{"OLANZAPINE": 11.72495542151455, "null": 1.9083570311291933}
\ No newline at end of file
+{"ZOSTAVAX": 81.48180796145834, "null": 0.8643050682675437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3737.json
index ec1ec066290..778f4aad1f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3737.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3737.json
@@ -1 +1 @@
-{"null": 1.1037392363797265}
\ No newline at end of file
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3738.json
index ca227fde234..4556ff34871 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3738.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3738.json
@@ -1 +1 @@
-{"COMIRNATY": 9.841936438014638, "COVID19": 1.5482594349981995, "ELLAONE": 4.733054172327333, "ESMYA": 3.937071567551048, "EVRA": 1.843482278554036, "MACITENTAN": 1.4620640590451293, "RYEQO": 18.50896560490084, "SPIKEVAX": 2.476769605779709, "TOZINAMERAN": 4.188963628794524}
\ No newline at end of file
+{"AVASTIN": 8.151443121089354, "CELLCEPT": 3.958275256274129, "CICLOSPORIN": 2.307705375021001, "CIMZIA": 4.433278504918567, "HUMIRA": 9.775429785752952, "NEXAVAR": 4.79876505324729, "ROACTEMRA": 123.6293763508997, "SUTENT": 2.418723208928036, "TOCILIZUMAB": 52.77297589269919, "XELJANZ": 1.9789438138995032, "null": 0.7749447588779672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3739.json
index bb6e4755c89..40c9a391815 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3739.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3739.json
@@ -1 +1 @@
-{"null": 1.1588647045126834}
\ No newline at end of file
+{"ABATACEPT": 0.220992708939733, "AFINITOR": 0.756398603162256, "AIMOVIG": 0.4972207011644819, "ALIMTA": 0.752591222400033, "ANAKINRA": 30.45770148026149, "ARANESP": 0.3571843754977494, "ARAVA": 1.4967932716696375, "AUBAGIO": 0.8779119957976547, "AVASTIN": 1.2169616863103017, "AZATHIOPRINE": 1.3999672399913827, "BELIMUMAB": 4.885846385773479, "BENLYSTA": 2.693095472601253, "BYDUREON": 0.6752774912046313, "BYETTA": 4.721437047471437, "CELLCEPT": 1.9798294181590872, "CHAMPIX": 0.3002019913696855, "CIALIS": 2.856407711537741, "CICLOSPORIN": 0.3610700460142222, "CIMZIA": 1.6640582062745823, "CLOPIDOGREL": 0.8189119151900834, "COMIRNATY": 0.1570459448698122, "COSENTYX": 2.803880264247209, "CYMBALTA": 0.310613663423506, "DEXAMETHASONE": 0.6945656307043768, "ELIQUIS": 1.7968767799231768, "ENBREL": 3.0513563184282013, "ENTYVIO": 1.1358689928410488, "ESBRIET": 2.5523542382089084, "EVISTA": 1.4847548013596072, "EXJADE": 1.1779991620974517, "FASLODEX": 0.5109998059294633, "FIRDAPSE": 3.7990582536834814, "FORSTEO": 1.511564276102059, "HIZENTRA": 3.3352560015802117, "HUMALOG": 0.6131032798218801, "HUMIRA": 2.050816176524973, "HYDROCORTISONE": 1.1977717434835111, "IBRANCE": 2.331037422962926, "IBUPROFEN": 0.6275747689603688, "INFLIXIMAB": 3.4099816299741588, "INLYTA": 1.225317117313231, "JANUMET": 1.690924745351598, "JANUVIA": 1.4660307910898338, "JARDIANCE": 0.3882240779728036, "KEYTRUDA": 0.3900124741458481, "LANTUS": 0.7776866579360701, "LEFLUNOMIDE": 14.434827699008416, "LYRICA": 1.012893876679131, "MEPOLIZUMAB": 1.113573087689905, "METHOTREXATE": 4.261275584389175, "MICARDIS": 0.7529486937947463, "NEXAVAR": 0.4006787048973459, "NPLATE": 1.0123546694724614, "NUCALA": 0.6223646122841556, "OFEV": 3.2795509670615868, "OMALIZUMAB": 0.4329940861678279, "OPDIVO": 0.4655001281165154, "OPSUMIT": 0.8772109241248693, "OZEMPIC": 13.970443235637882, "PEGASYS": 0.9807843975668477, "PLAVIX": 0.8668319372943956, "REMICADE": 2.2147523230037782, "REVATIO": 1.0236965112166343, "RINVOQ": 5.060329565299181, "RITUXIMAB": 1.569967770950339, "ROACTEMRA": 25.15011757391077, "SAXENDA": 3.9104814756767343, "SHINGRIX": 0.5563529865314404, "SIMPONI": 3.9339476961592954, "SOLIRIS": 0.9191368625481164, "SPIKEVAX": 0.177810930173325, "SPRYCEL": 0.6644630179364799, "STELARA": 2.469011569935597, "STIVARGA": 0.5798695951501406, "SUTENT": 0.7842134918612171, "TASIGNA": 0.6183482682450435, "TOCILIZUMAB": 11.347052098873828, "TOZINAMERAN": 0.2931558316632473, "TRELEGY": 1.6392114673675178, "TREMFYA": 3.63600347891442, "VAXZEVRIA": 0.089202946748824, "VELTASSA": 1.8561256089093756, "VIAGRA": 1.0160608370040796, "VICTOZA": 1.4345171562226724, "VOTRIENT": 1.6345266818877149, "XELJANZ": 7.399133547917933, "XOLAIR": 1.4083712827921546, "XTANDI": 0.7430665349660358, "YERVOY": 1.6794317109987558, "ZOSTAVAX": 1.5700648211879062, "ZYPREXA": 0.1975313643979479, "null": 1.7451736333041814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/374.json
index 07b1dccd900..a779db4d9bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/374.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/374.json
@@ -1 +1 @@
-{"STELARA": 12.855936280553156, "null": 1.1565303138441263}
\ No newline at end of file
+{"null": 2.147225067505238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3740.json
index fde112f376d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3740.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3740.json
@@ -1 +1 @@
-{"null": 2.685437891924619}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3741.json
index a1766ede455..cc1daf9729f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3741.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3741.json
@@ -1 +1 @@
-{"ABATACEPT": 18.727975104458583, "ACETAMINOPHEN": 67.5917558636739, "ADALIMUMAB": 32.68494344561906, "APREMILAST": 14.214965474978568, "APREPITANT": 82.99315107728042, "ARAVA": 31.054248932287692, "BIKTARVY": 2.1989374407539364, "BUMETANIDE": 3.866311578004487, "CIMZIA": 4.9750139638081565, "COSENTYX": 1.2299485670411516, "EFAVIRENZ": 2.4070585561439413, "ERELZI": 10.99665305584431, "HYDROCORTISONE": 1.642151027962219, "INTRONA": 2.507787583909556, "JANUMET": 2.155701288818075, "MYCOPHENOLATE": 2.1221157607758925, "RITUXIMAB": 3.749615427759577}
\ No newline at end of file
+{"ELIQUIS": 14.203853018844631, "PLAVIX": 29.51120427833756, "null": 0.9746755302697496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3742.json
index 12de83256b2..e0e7d97195e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3742.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3742.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 5.98689183606869, "ELIQUIS": 2.877076278470465, "null": 2.2107096800193835}
\ No newline at end of file
+{"RINVOQ": 93.13321749475104, "null": 0.2917457831743803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3743.json
index e9a40923549..98e724f1578 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3743.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3743.json
@@ -1 +1 @@
-{"null": 1.633195873882193}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3744.json
index 69de482953a..82df7d26f6c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3744.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3744.json
@@ -1 +1 @@
-{"VAXZEVRIA": 1.0256861909502704, "null": 1.3110463400425465}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3745.json
index f8a95c9a21f..cf092988a4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3745.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3745.json
@@ -1 +1 @@
-{"COMIRNATY": 6.830589123450165, "SPIKEVAX": 1.6751663705265951}
\ No newline at end of file
+{"BRILIQUE": 6.5138230680150695, "CLOPIDOGREL": 23.161278802389216, "EFIENT": 98.73199944516794, "ELIQUIS": 32.99173967165946, "LIXIANA": 20.619695137050822, "NEXAVAR": 2.33225968549136, "PLAVIX": 31.83007003235699, "RINVOQ": 6.284673034019529, "XARELTO": 52.14436765853645, "null": 0.8063794612185685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3746.json
index ac8f30e7677..20d4b864835 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3746.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3746.json
@@ -1 +1 @@
-{"BORTEZOMIB": 25.0625688570322, "ELIQUIS": 1.879183829912633}
\ No newline at end of file
+{"null": 2.778200114793397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3747.json
index 8920db739a5..ded352c9703 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3747.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3747.json
@@ -1 +1 @@
-{"null": 2.589912226151715}
\ No newline at end of file
+{"null": 0.8400700673806651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3748.json
index a4a665349f5..f488e091631 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3748.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3748.json
@@ -1 +1 @@
-{"HUMAN": 29.070209625223576}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3749.json
index d7471c80df4..e1b7033905c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3749.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3749.json
@@ -1 +1 @@
-{"COMIRNATY": 2.0402453882154927}
\ No newline at end of file
+{"AMBRISENTAN": 209.7620579019165, "COMIRNATY": 1.4134845741040545, "LYRICA": 9.742299963809849, "SPIKEVAX": 1.4848138892890126, "TOZINAMERAN": 3.262931345473014, "VAXZEVRIA": 2.521446799598825, "null": 0.2219683912224976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/375.json
index 9ac04a483f5..3978d692937 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/375.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/375.json
@@ -1 +1 @@
-{"null": 1.2512093287123718}
\ No newline at end of file
+{"MIRCERA": 378.5960489497312, "null": 0.6127986984377405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3750.json
index bf0a1ee43ec..ec066c3350b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3750.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3750.json
@@ -1 +1 @@
-{"COMIRNATY": 7.861926840932619}
\ No newline at end of file
+{"ABILIFY": 0.5764922630768824, "APIDRA": 1.2649427184549429, "ARIPIPRAZOLE": 0.5491595546009039, "BRILIQUE": 1.4489479419426, "BYDUREON": 3.146932962367571, "CHAMPIX": 0.748554722866801, "CLOPIDOGREL": 1.4553323249707295, "COMIRNATY": 0.8379928167355175, "CYMBALTA": 0.9733788069113166, "ELIQUIS": 0.5422480576108435, "ENTRESTO": 4.6962221369103645, "ESOMEPRAZOLE": 1.709510296052957, "EXFORGE": 1.0123723446078534, "FORXIGA": 1.405349701752754, "GARDASIL": 2.8182796627603803, "HYDROCORTISONE": 3.2811280889894068, "IBRANCE": 0.4503929892068152, "IBUPROFEN": 0.5498331223034529, "JANUVIA": 0.5950464689414272, "JARDIANCE": 0.5629403890912759, "KEPPRA": 0.284967811721016, "KEYTRUDA": 0.5270525202506001, "MODERNA": 2.4012530381011645, "NIMENRIX": 1.9048156553166204, "OCRELIZUMAB": 8.774033439835945, "OMALIZUMAB": 1.0663989278445245, "OPSUMIT": 2.293706314133316, "OXYBUTYNIN": 3.83776226896576, "PEGASYS": 0.2741667722650979, "PEGINTRON": 0.3491399276201329, "SPIKEVAX": 0.8900426749173951, "STELARA": 1.245921501295361, "SUTENT": 0.1130857540623772, "TOZINAMERAN": 4.191479627079974, "VAXZEVRIA": 4.491332059504437, "XELJANZ": 0.3614812516358681, "XTANDI": 0.522546207169608, "null": 0.6225151143721002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3751.json
index e30a11521ec..f15d309801e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3751.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3751.json
@@ -1 +1 @@
-{"COMIRNATY": 4.84615206062194}
\ No newline at end of file
+{"null": 10.61799530591728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3752.json
index 6da6e667bec..f3d9ac3b98a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3752.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3752.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"null": 1.7303640841198316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3753.json
index 50327f392d4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3753.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3753.json
@@ -1 +1 @@
-{"COMIRNATY": 8.324923275330095, "SPIKEVAX": 1.8187805276654383, "VAXZEVRIA": 1.112339043176286}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3754.json
index 1aa1c5e7004..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3754.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3754.json
@@ -1 +1 @@
-{"COMIRNATY": 7.000938039619148, "SPIKEVAX": 1.6530182894990306, "TOZINAMERAN": 1.1029607303776785, "VAXZEVRIA": 2.688403272577601}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3755.json
index 3bd584ba4b7..89895fa5128 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3755.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3755.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 2.2344852332545564, "ALISKIREN": 73.63442192676031, "ASPARAGINASE": 2.663729352423599, "AUBAGIO": 4.847130669815748, "AVANDAMET": 3.0169948322825304, "AVANDIA": 3.3782616450182954, "BENLYSTA": 1.2935912437492267, "BETAFERON": 3.0333922882343907, "BEVACIZUMAB": 3.586357284777744, "BRILIQUE": 1.207651381065122, "BRIVIACT": 4.707708162999949, "CICLOSPORIN": 1.6861403797249024, "CIDOFOVIR": 11.18727847729707, "CLOPIDOGREL": 3.952761704056571, "COMBIVIR": 1.6584243884191092, "COMIRNATY": 1.3292256495454975, "CYTARABINE": 1.4047506939691514, "DOXORUBICIN": 1.007334523630624, "EFAVIRENZ": 4.6888029409541545, "ELIQUIS": 2.3362342165037644, "ENOXAPARIN": 5.047901729147991, "EVISTA": 1.370036327230146, "EYLEA": 2.189787587209978, "FAMPYRA": 2.259897341654898, "GARDASIL": 1.053241490750744, "GLIBENCLAMIDE": 4.794773706938801, "IRBESARTAN": 2.7166888161911498, "JAKAVI": 1.243343207220296, "KESIMPTA": 4.338213268122822, "LACOSAMIDE": 1.3506389228782227, "LEMTRADA": 3.0226481991745717, "LEVETIRACETAM": 1.1056133543205855, "LIXIANA": 6.195765618403061, "MYCOPHENOLATE": 1.5124678224265324, "NOT": 1.9031745767903607, "NOVOSEVEN": 4.604553943933594, "PLAVIX": 2.916338004213289, "RIVAROXABAN": 6.69434751972392, "SILDENAFIL": 1.3309390523236078, "TASIGNA": 1.9676345870779937, "TEMODAL": 4.2291840001044765, "TEMOZOLOMIDE": 7.634211518217326, "TWINRIX": 1.6637854063621529, "VAXZEVRIA": 1.0683465683567217, "VIAGRA": 1.960053095729396, "XARELTO": 1.622328589469063, "YESCARTA": 1.3678697494635372}
\ No newline at end of file
+{"CARBIDOPA": 182.44633487782136, "ENTACAPONE": 672.2742716305228, "LEVODOPA": 2264.228123339601, "STALEVO": 223.59585536084668, "null": 0.575304435333259}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3756.json
index a17df3ddfc6..2e2d782b0dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3756.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3756.json
@@ -1 +1 @@
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\ No newline at end of file
+{"null": 2.7788528893171547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3757.json
index 34f9a7d745b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3757.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3757.json
@@ -1 +1 @@
-{"COVID19": 3.035055365627608, "FENTANYL": 14.850888533746913, "KAFTRIO": 50.70549145749571, "TOZINAMERAN": 6.413513610711707}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3758.json
index 955db224ebb..6f67beeb341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3758.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3758.json
@@ -1 +1 @@
-{"ISENTRESS": 480.74761012803054, "null": 1.4880491677565826}
\ No newline at end of file
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3759.json
index ee825133c95..9263fa5f5ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3759.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3759.json
@@ -1 +1 @@
-{"CUBICIN": 10.959818262048946, "GARDASIL": 6.845010088781863, "LEVOFLOXACIN": 2.1935999456022794, "MMRVAXPRO": 4.151781861430987, "PLAVIX": 1.931204041438756, "STELARA": 2.8506316466668613, "TAMIFLU": 4.087286149918017, "TWINRIX": 9.319312592505446, "null": 2.2455087807647858}
\ No newline at end of file
+{"SYNAGIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/376.json
index e125c437264..048f42cf349 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/376.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/376.json
@@ -1 +1 @@
-{"null": 1.3285918677219326}
\ No newline at end of file
+{"null": 2.2434296420663644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3760.json
index c1ddd26a022..bdb45a6cc18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3760.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3760.json
@@ -1 +1 @@
-{"null": 1.4824843710479705}
\ No newline at end of file
+{"null": 2.9174552154458926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3761.json
index 71c0d5c868e..59de4873846 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3761.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3761.json
@@ -1 +1 @@
-{"ARIXTRA": 17.00200692193224, "BIVALIRUDIN": 175.5513554064213, "CLOPIDOGREL": 1.490574344742214, "ENOXAPARIN": 124.1118873726466, "INHIXA": 33.89343939392273, "null": 10.182253128045916}
\ No newline at end of file
+{"null": 0.7688781030861545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3762.json
index 15b59906ab1..6f67beeb341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3762.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3762.json
@@ -1 +1 @@
-{"null": 9.293779407489364}
\ No newline at end of file
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3763.json
index c82636c0c7c..f099cbb8179 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3763.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3763.json
@@ -1 +1 @@
-{"COVID19": 1.2299833099732955, "VAXZEVRIA": 9.700509811932166, "null": 1.589362582183231}
\ No newline at end of file
+{"null": 0.3528265731859907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3764.json
index 1b7c6a628e9..02957dd7701 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3764.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3764.json
@@ -1 +1 @@
-{"null": 1.00826282472859}
\ No newline at end of file
+{"null": 0.8910504781680227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3765.json
index 8ecae6a477c..1a14e565949 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3765.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3765.json
@@ -1 +1 @@
-{"null": 2.52244442391094}
\ No newline at end of file
+{"VAXZEVRIA": 0.5596464003010996, "null": 1.1064994325685191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3766.json
index 1c8f5664a70..9428bfca642 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3766.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3766.json
@@ -1 +1 @@
-{"NOT": 316.24411147327004, "PEGINTRON": 65.52921356671662}
\ No newline at end of file
+{"null": 0.3900087783156435}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3767.json
index b81b114bff4..79640ff131c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3767.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3767.json
@@ -1 +1 @@
-{"AVASTIN": 42.75373858081608, "null": 2.624735161095654}
\ No newline at end of file
+{"ABILIFY": 3.255378710731277, "AIMOVIG": 1.6334495112992529, "ARIPIPRAZOLE": 5.503964042654358, "COMIRNATY": 0.2184549230375944, "CYMBALTA": 0.9728950786155528, "GARDASIL": 2.0679736900465224, "KEPPRA": 3.610613077269485, "LANTUS": 0.5947297077279233, "LATUDA": 10.254229855473769, "LEVETIRACETAM": 3.07628284858598, "MMRVAXPRO": 6.935784455908836, "OLANZAPINE": 3.499488298153398, "PEGASYS": 0.5085185889156357, "SPIKEVAX": 0.3140757917988622, "TOZINAMERAN": 1.1525220093321824, "VAXZEVRIA": 0.165293362972005, "ZYPREXA": 10.59189724131937, "null": 2.3926557928764955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3768.json
index cac4c077e65..9282cefa5a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3768.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3768.json
@@ -1 +1 @@
-{"BARACLUDE": 46.23848180227015, "BYETTA": 2.947015358870562, "CABOMETYX": 3.132317733957516, "DACLATASVIR": 7.679390704427341, "DAKLINZA": 13.093020709827162, "DARUNAVIR": 9.530161096996478, "ELIQUIS": 1.0715288788373558, "ENTECAVIR": 8.954113847391804, "EPCLUSA": 7.215967324859996, "EXFORGE": 1.2993724861160203, "FORSTEO": 1.2590176122167296, "HARVONI": 14.97648138783986, "HEPSERA": 18.086266146471115, "JANUMET": 2.089256003013672, "JANUVIA": 1.795122608747373, "JARDIANCE": 1.1140860383433746, "KALETRA": 4.897371608997988, "LANTUS": 1.7133567777579617, "LEVEMIR": 1.1900133375541195, "NEXAVAR": 26.53183321462419, "OLYSIO": 5.621424277234415, "PEGASYS": 2.730850008307717, "PEGINTERFERON": 2.6258783517408126, "PEGINTRON": 2.160604981712785, "REBETOL": 4.745768428083379, "RIBAVIRIN": 7.509593228685498, "SOVALDI": 14.629033122198743, "STELARA": 1.166348183776871, "STIVARGA": 1.9323015404876656, "TRELEGY": 1.5624969488292637, "VEMLIDY": 20.873704873934525, "VICTOZA": 1.2049602066959335, "VIREAD": 2.784639777042697, "null": 3.804735377848458}
\ No newline at end of file
+{"COMIRNATY": 0.1272844941148305, "FORSTEO": 12.753593277078698, "KEPPRA": 6.262087241266308, "LEVETIRACETAM": 15.394828611129451, "SPIKEVAX": 0.2767870824198321, "VIMPAT": 21.328565401013428, "null": 1.6410402401914914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3769.json
index 9dfeb18be68..4e8981dbdc9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3769.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3769.json
@@ -1 +1 @@
-{"BYETTA": 28.547028122901526, "NEXAVAR": 22.59660865467791}
\ No newline at end of file
+{"null": 0.6997812771283896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/377.json
index 2668adb2a56..eabaa4894bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/377.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/377.json
@@ -1 +1 @@
-{"ARAVA": 1.4338745798084156, "AZATHIOPRINE": 10.507514332225952, "BUDESONIDE": 2.206837254518756, "CIMZIA": 1.394659916004577, "ENTYVIO": 15.457887635142932, "HUMIRA": 10.3175946154638, "INCIVO": 11.846661823899442, "INFLECTRA": 100.29983673199862, "PEGASYS": 2.238158940034937, "ROTATEQ": 13.289277331478871, "STELARA": 2.3109883352988483, "SUTENT": 4.543848224075102, "null": 1.1581077165163125}
\ No newline at end of file
+{"ATRIPLA": 2.505821738646417, "CHAMPIX": 13.309913500993988, "COMIRNATY": 0.1153566750448358, "CYMBALTA": 4.040775733433027, "FENTANYL": 6.6257225996736535, "null": 2.003390693311394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3770.json
index 4b9bd0a8d6a..08bba906bc4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3770.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3770.json
@@ -1 +1 @@
-{"HARVONI": 229.73980363895225, "NEXAVAR": 23.004327011639884, "PEGASYS": 8.891482554877246, "SOVALDI": 602.0039890255414}
\ No newline at end of file
+{"BUPRENORPHINE": 11.91443177301148, "COMIRNATY": 0.2310376519061774, "GARDASIL": 3.357622485606285, "null": 2.0024052619148542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3771.json
index 888b99eb463..7447fa769fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3771.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3771.json
@@ -1 +1 @@
-{"NEXAVAR": 21.91977100199012, "null": 1.6645274913659105}
\ No newline at end of file
+{"ABILIFY": 1.6166200914249584, "AERIUS": 0.4512351067784735, "ALLI": 11.680945098091678, "APIXABAN": 0.4006948616845928, "ARIPIPRAZOLE": 3.425447957719108, "ASENAPINE": 17.210980663496287, "BENZODIAZEPINE": 50.48282359227272, "BENZODIAZEPINES": 21.311868883850032, "BIKTARVY": 0.4474139080343012, "BORTEZOMIB": 0.4900136572781381, "BOTULINUM": 0.957539281002088, "BRINTELLIX": 0.5709524890573915, "BUDESONIDE": 0.1420836592689404, "BUMETANIDE": 0.9412886785597364, "BUPRENORPHINE": 21.702545013072967, "CAFFEINE": 25.059676152125206, "CANNABIDIOL": 17.285453545261063, "CHAMPIX": 0.0503963946849948, "CYMBALTA": 0.644958133820115, "DEXAMETHASONE": 0.1258638982849658, "DULOXETINE": 3.464648549680456, "EFAVIRENZ": 2.585471618930736, "ELIQUIS": 0.0465780187312672, "ENBREL": 0.3056859472450343, "ENTACAPONE": 2.378851309861442, "ESOMEPRAZOLE": 0.3275586797190141, "FENTANYL": 17.2863932240658, "GARDASIL": 0.0422862508282601, "HUMALOG": 0.0494898256155721, "IBUPROFEN": 3.3190646431895936, "INSULIN": 0.2814956428884726, "INVEGA": 1.522019633781727, "IRBESARTAN": 0.3230836936064448, "KEPPRA": 0.82845473763129, "LANTUS": 0.1135708777818118, "LATUDA": 0.645322174693926, "LEVETIRACETAM": 1.8247051648162944, "LEVODOPA": 3.159321513760441, "LEVOFLOXACIN": 1.3218199938057933, "LOXAPINE": 15.312618666358835, "LYRICA": 4.528757954297011, "MELATONIN": 1.3291454497062225, "MICARDIS": 0.2206377214810642, "MIDAZOLAM": 3.741359498668552, "MUSCLE": 72.59094091393193, "NALOXONE": 5.4057542540033925, "NOT": 8.004700452066203, "NUCALA": 0.0819442878767492, "OLANZAPINE": 4.671555795015489, "OPIACE": 90.323352896149, "OPIOID": 43.20457782376957, "OPIOIDS": 32.69048150657904, "OTHER": 7.128216886330796, "OXYBUTYNIN": 2.3103916557890805, "PALIPERIDONE": 3.801343130606583, "PANTOPRAZOLE": 0.2940103410678623, "PEGASYS": 0.2118115846440166, "PEGINTRON": 0.1579328182604996, "PLAVIX": 0.0587104998781001, "POPPERS": 128.15299715990255, "PREGABALIN": 18.791472966754554, "PROPRANOLOL": 0.8200207085066591, "PTC": 113.0037911801918, "RISPERIDONE": 1.7768276073362907, "SIFROL": 0.994250494072004, "SILDENAFIL": 1.980861198977342, "SODIUM": 8.448666755634182, "SOMATROPIN": 4.682739818575517, "SUBOXONE": 12.365476970842847, "SUBSTANCE": 86.9809708477372, "TESTOSTERONE": 12.926828588353708, "UNKNOWN": 2.931927045546745, "UNSPECIFIED": 11.469858188622805, "VIAGRA": 0.8977469224784254, "VIMPAT": 0.2826283382025204, "XYREM": 2.331073061463816, "ZYPREXA": 0.8004217281812572, "null": 7.060169793415368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3772.json
index 981aa2f4d5e..8f6ba677826 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3772.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3772.json
@@ -1 +1 @@
-{"ABACAVIR": 2.746889785944175, "ACTOS": 4.167640976238321, "ADALIMUMAB": 2.612448250737179, "ADCIRCA": 7.033824432351459, "AMINOSALICYLIC": 2.646538969577636, "ARAVA": 1.8443896530045751, "ATAZANAVIR": 1.3914471724514657, "AVANDIA": 2.595557005903756, "AVASTIN": 1.0983026577984003, "BARACLUDE": 21.07978926239514, "BETAFERON": 1.7985341307157163, "BIKTARVY": 3.250563380271834, "BOCEPREVIR": 7.646238729680586, "BOTULINUM": 3.0957041641103524, "BYDUREON": 1.0465084162722955, "BYETTA": 3.053137954394757, "CAPECITABINE": 1.4897910572067738, "CERTOLIZUMAB": 18.610653760146523, "CICLOSPORIN": 1.6275510154485495, "COAPROVEL": 1.6453705638049567, "COSENTYX": 1.841864496986104, "CRIXIVAN": 4.080061379530517, "CYMBALTA": 2.14385500315432, "DACLATASVIR": 17.979465592968364, "DAKLINZA": 15.425507515045556, "EFAVIRENZ": 2.6959362093716166, "ENTECAVIR": 17.91011149176656, "ENTYVIO": 1.0376077201229337, "EPCLUSA": 29.92627406492871, "EPIVIR": 10.081449847375742, "EXJADE": 2.352722657010078, "EXVIERA": 34.06868530255819, "FASLODEX": 1.3031308824664778, "HALAVEN": 2.8865913712369187, "HARVONI": 17.77469453588154, "HEPSERA": 8.428477113072669, "HUMALOG": 1.9746396564723108, "HUMIRA": 1.0617067172080692, "INCIVO": 8.140975922628007, "INTELENCE": 10.659739972018835, "INTERFERON": 8.66354073960194, "INTRONA": 7.215738714312078, "INVIRASE": 7.95494270063493, "ISENTRESS": 2.346150348155201, "JAKAVI": 1.2736085837048934, "JANUMET": 4.982316660693261, "JANUVIA": 2.62291633798551, "JARDIANCE": 1.0757605192695632, "KAFTRIO": 3.7729948421462094, "KALETRA": 1.8049363029342005, "LAMIVUDINE": 2.423112709854484, "LANTUS": 1.471488552939361, "LEVEMIR": 2.489053552219734, "METHOTREXATE": 2.402973221822516, "MULTAQ": 1.4533071264308648, "MYCOPHENOLATE": 1.391505539886466, "NEXAVAR": 3.32044331466792, "NPLATE": 5.375563519809614, "OBETICHOLIC": 52.45252841805807, "OCALIVA": 44.77995960243233, "OLYSIO": 12.51313699003402, "OPSUMIT": 2.2101121475318863, "PANTOPRAZOLE": 1.1029122477269715, "PEGASYS": 10.55538089373633, "PEGINTERFERON": 5.24890516232784, "PEGINTRON": 6.160783178397923, "REBETOL": 6.238490070092362, "REVATIO": 2.2934915622820333, "REYATAZ": 3.768678234504326, "RIBAVIRIN": 18.211423949475275, "SKYRIZI": 5.032679332844837, "SOLIRIS": 1.0389502788819165, "SOMATROPIN": 26.67277078647569, "SOVALDI": 22.786745654044303, "STELARA": 2.728134725249486, "SUBOXONE": 1.8297664199515216, "TASIGNA": 1.153892929146991, "TRACLEER": 3.263835706207077, "TREMFYA": 2.213911939508271, "TRULICITY": 1.18830830170811, "VICTOZA": 2.083593490886563, "VIRAMUNE": 6.312214284861156, "VIREAD": 4.001487236745732, "ZEPATIER": 12.134097510682}
\ No newline at end of file
+{"BUPRENORPHINE": 19.685343215666727, "LYRICA": 4.989802007567006, "null": 12.337982258166589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3773.json
index 75ea6edb9f8..4b6e90d1138 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3773.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3773.json
@@ -1 +1 @@
-{"ADENURIC": 24.891713854811687, "ARAVA": 1.319561213014227, "BYETTA": 10.055521341695576, "CARMUSTINE": 29.015323312332637, "CLOPIDOGREL": 2.239564526449165, "IBRANCE": 1.4325404924869116, "JANUMET": 17.3324503987451, "JANUVIA": 11.927521072229212, "KEYTRUDA": 1.851152046184869, "MEPOLIZUMAB": 7.429126593250801, "NEXAVAR": 2.2306814444562675, "PEGASYS": 1.976702336261432, "SUTENT": 1.2263762787567267, "ZOSTAVAX": 2.336137971959278}
\ No newline at end of file
+{"INSULIN": 77.05478915919373, "null": 1.8327675420226417}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3774.json
index 4c66795efe7..d33e9e3c290 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3774.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3774.json
@@ -1 +1 @@
-{"ADENURIC": 5.323263611438191, "AERIUS": 9.83462487345191, "ALIMTA": 6.05624656232113, "AMIKACIN": 7.032462262712173, "APROVEL": 7.711552929596273, "APTIVUS": 10.8942409411567, "ARIXTRA": 4.972557145476923, "ASPARAGINASE": 1.637872975770662, "AUBAGIO": 1.6964526038904386, "BIKTARVY": 2.354104322739183, "BOSULIF": 2.179710639736524, "BRAFTOVI": 4.542024099430119, "BRILIQUE": 3.1929362253178963, "BRINTELLIX": 1.1372388725765716, "BUSILVEX": 18.580576274601707, "BUSULFAN": 1.3669167399673507, "CABOMETYX": 2.5096515394877303, "CANCIDAS": 10.427131539869697, "CASPOFUNGIN": 2.7210209117409585, "CELLCEPT": 1.4951768468949964, "CELSENTRI": 6.362524548674013, "CIRCADIN": 4.117291280695244, "COAPROVEL": 2.0847063666885, "COMBIVIR": 4.044839150019739, "COMPLEMENT": 48.42793068909916, "COTELLIC": 9.540794144793823, "CRESEMBA": 4.711618031890461, "CUBICIN": 4.97017628584627, "DABRAFENIB": 1.8170445797358965, "DARZALEX": 1.8004346266676752, "DESLORATADINE": 2.5158029448369725, "DEXAMETHASONE": 2.454616603880561, "DIFICLIR": 7.859223317313034, "EBIXA": 10.286120693337152, "EFAVIRENZ": 11.49964335023513, "ELIQUIS": 1.1251830823139253, "EMEND": 11.330596347800826, "EMTRIVA": 4.842451934203848, "ENOXAPARIN": 1.9504789842336123, "EPIVIR": 1.8472939874826004, "ESOMEPRAZOLE": 5.936194455305411, "EUCREAS": 3.6749664536199433, "EVOLTRA": 36.54017759660096, "EXELON": 5.121763974210132, "EXJADE": 1.9713299814567395, "EXVIERA": 2.193932514797939, "FASLODEX": 1.0307407841832794, "FASTURTEC": 13.067967373960176, "FYCOMPA": 2.4883904648832336, "GALVUS": 5.882952060704632, "GAZYVARO": 8.076937563672756, "GLIVEC": 2.734300830273523, "ICLUSIG": 1.389965392727581, "INLYTA": 2.0731826563986324, "IPILIMUMAB": 2.302952221648148, "IRBESARTAN": 2.135199549619509, "IRESSA": 2.3240790738734174, "ISENTRESS": 12.560668733302348, "JAKAVI": 1.0496570477885925, "KAFTRIO": 5.696746927502789, "KALETRA": 12.533421129606683, "KEPPRA": 4.685534274243059, "KEYTRUDA": 2.5013597715836724, "KISQALI": 8.661838990026082, "KIVEXA": 11.390235639115737, "LOPINAVIR/RITONAVIR": 122.11118204794056, "LUMYKRAS": 58.380440353621815, "LYRICA": 3.411137044179161, "MABTHERA": 3.685245391831023, "MEKINIST": 5.374563372540807, "MELPHALAN": 2.902636152879413, "MERCAPTOPURINE": 1.7507979124133002, "METHOTREXATE": 3.384673012885153, "MIDAZOLAM": 3.158776278356403, "MYCAMINE": 10.635830280939317, "NORVIR": 17.42151593690474, "NOVONORM": 9.237396918335149, "NOXAFIL": 16.68721068391925, "OFEV": 2.5698406498407995, "OLANZAPINE": 1.4692418101677165, "ONCASPAR": 2.109524913435433, "OPDIVO": 4.644697985158562, "ORKAMBI": 3.0588832808065307, "PACLITAXEL": 1.136283650393076, "PANTOPRAZOLE": 6.173434281908447, "PEMBROLIZUMAB": 1.83500313815028, "POSACONAZOLE": 7.092548135780718, "PRADAXA": 3.5239655153759184, "PREGABALIN": 2.127093626981684, "PROTELOS": 3.4730874065387947, "REMICADE": 1.036861807040688, "REVATIO": 1.3771380373423874, "REYATAZ": 14.384184440457895, "RIXATHON": 9.220755875308834, "ROACTEMRA": 5.702460799916748, "SUFENTANIL": 7.54066673128345, "TAGRISSO": 1.4291231029329, "TAMIFLU": 4.7576935499245865, "TEMODAL": 11.07514157520685, "TIVICAY": 2.5171205234106626, "TOCILIZUMAB": 2.26173701865858, "TRACLEER": 2.748228101769231, "VEKLURY": 4.614005283067123, "VENETOCLAX": 1.3588306978676603, "VFEND": 8.46995234714188, "VICTOZA": 1.0992445756731068, "VIMPAT": 1.4691864857608523, "VIRAMUNE": 5.169643190242111, "VIREAD": 1.0350593188994228, "VORICONAZOLE": 5.309468917463771, "VOTRIENT": 3.0587464472888755, "XALKORI": 1.9121046615813388, "XARELTO": 1.649077324886682, "YERVOY": 3.0311805394802147, "YONDELIS": 19.964846515916463, "ZELBORAF": 2.458740477873069, "ZYPREXA": 1.3376856267666473, "null": 1.8740138036310452}
\ No newline at end of file
+{"null": 12.192310475902794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3775.json
index 43309a6af40..9b83acff82c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3775.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3775.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 1.7580159077347244, "ASPARAGINASE": 5.06722416348333, "AZATHIOPRINE": 1.3599886033603783, "BARACLUDE": 14.602783825908674, "BOCEPREVIR": 11.507872578266722, "BUSULFAN": 1.6975286107568592, "CABOMETYX": 6.089680791488418, "CAPECITABINE": 1.646753076633848, "DACLATASVIR": 21.348871507731868, "DAKLINZA": 16.162011192807157, "EPCLUSA": 25.13926692887764, "EXJADE": 1.2321882635987178, "EXVIERA": 45.286269277756666, "FASLODEX": 1.0473763055259997, "FUZEON": 61.340033465269, "HARVONI": 20.57371811762984, "INCIVO": 3.016371032849432, "INTRONA": 5.475564904564629, "IRINOTECAN": 2.5169210702850555, "LAMIVUDINE": 11.26171137728526, "LENVIMA": 128.29548863085378, "LEVETIRACETAM": 1.7423673437331295, "MIDAZOLAM": 1.8132384292780956, "NEXAVAR": 42.154087398225926, "NPLATE": 1.831962684180476, "OCALIVA": 12.694429734823943, "OLYSIO": 20.83149632821512, "OPDIVO": 1.471165055236392, "OPSUMIT": 1.4429290246458863, "PANITUMUMAB": 23.76121476728033, "PEGASYS": 5.130926981523602, "PEGINTERFERON": 6.438705734719675, "PEGINTRON": 6.377218557353179, "REBETOL": 15.975200747232927, "RIBAVIRIN": 15.927670214224351, "RITUXIMAB": 1.310880448637901, "SAMSCA": 30.619023253576987, "SOMATROPIN": 44.40357586596575, "SORAFENIB": 10.293247755647284, "SOVALDI": 28.74600624895768, "STIVARGA": 16.78642664509995, "VFEND": 1.4132162373100037}
\ No newline at end of file
+{"ASPARAGINASE": 41.24009998524599, "DEXAMETHASONE": 12.751456599435016, "METHOTREXATE": 20.14757276089974, "TOBRAMYCIN": 142.21029874448897, "null": 1.2677389988231151}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3776.json
index ea2123e810c..a85eb4f775d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3776.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3776.json
@@ -1 +1 @@
-{"AUBAGIO": 3.6084806801509264, "AZATHIOPRINE": 4.561878525028004, "CLOPIDOGREL": 3.489933948304826, "COSENTYX": 3.670627463410838, "CYMBALTA": 1.3671494879243846, "ENBREL": 3.4964052039680613, "EXJADE": 1.7482894985235709, "FASLODEX": 2.501084647093605, "HUMIRA": 1.9155086410037985, "IBRANCE": 1.4127524932496716, "INLYTA": 3.9921451382715145, "KEPPRA": 1.7242711504652393, "KEYTRUDA": 1.035665836796811, "MEKINIST": 2.606531854955437, "METHOTREXATE": 2.7086943387108438, "OLANZAPINE": 2.067889832339695, "OPSUMIT": 2.013816510584633, "SUTENT": 1.4857532023949365, "TRACLEER": 3.5663816642106645, "VFEND": 3.046953638345157, "VOTRIENT": 2.2391631483056647, "XELJANZ": 1.415503513534485, "ZYPREXA": 2.7636323268437946, "null": 1.343003526488603}
\ No newline at end of file
+{"null": 0.5354349791190777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3777.json
index 42cd2a26061..3db3e2be469 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3777.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3777.json
@@ -1 +1 @@
-{"ABACAVIR": 16.164598524776167, "ABATACEPT": 5.273447907018985, "ACETAMINOPHEN": 14.27090988199706, "ACLASTA": 2.8789150738840488, "ACLIDINIUM": 6.53294544579161, "ADALIMUMAB": 5.5895556775546815, "ADENURIC": 1.2042256308080856, "AERIUS": 1.053737144446347, "AGOMELATINE": 4.059472798678062, "ALOXI": 8.90267033169458, "AMIKACIN": 3.0312665364121374, "AMINOSALICYLIC": 1.4561652280761563, "AMPRENAVIR": 8.899852357985706, "ANAKINRA": 1.198138088576119, "ANTIBIOTICS": 1.6865415508001511, "APREMILAST": 6.670186334260973, "APREPITANT": 16.99299136086368, "APTIVUS": 7.6700180362842625, "ARAVA": 8.841971590008157, "AUBAGIO": 3.8048579325186687, "AXITINIB": 1.5008004920911544, "AZATHIOPRINE": 2.412777288382531, "AZTREONAM": 3.312947252087437, "BEDAQUILINE": 3.2968357089789104, "BETAFERON": 2.4083389078484605, "BOSULIF": 2.170667410834908, "CABOMETYX": 1.966352395088313, "CANCIDAS": 3.208059300340692, "CANNABIDIOL": 2.034996503835309, "CARFILZOMIB": 1.1499088832472255, "CASPOFUNGIN": 1.076009137522819, "CEFUROXIME": 6.024051232638052, "CELLCEPT": 1.0160162513033208, "CELSENTRI": 3.340333528945695, "CICLOSPORIN": 1.3031123824053583, "CIMZIA": 2.1675295215674093, "COMBIVIR": 2.724196635579134, "CRESEMBA": 2.8910810707256016, "CYMBALTA": 1.0076483517851291, "DELAMANID": 6.460598504299959, "DENOSUMAB": 2.137608101974109, "DIFICLIR": 2.2150416323204, "EFAVIRENZ": 1.0804659740045963, "EMTRIVA": 3.491546694019553, "ENBREL": 3.25898124994273, "ENOXAPARIN": 2.753829415815492, "ENTECAVIR": 2.0664092384616937, "ENTYVIO": 1.0500053018421307, "EPIDYOLEX": 4.403209668746546, "EPIVIR": 1.1706505332164916, "ERELZI": 2.5714108491237915, "ESBRIET": 1.2000093116603463, "ESMYA": 9.362555270490866, "ESOMEPRAZOLE": 1.4362387651378496, "ETANERCEPT": 1.7885748446135303, "EVEROLIMUS": 1.1179385746934434, "EXJADE": 3.1724211683051777, "FASLODEX": 1.05684515849515, "FEBUXOSTAT": 2.880551215072052, "GALVUS": 1.1502751135408524, "GANCICLOVIR": 1.6380717886771528, "GEFITINIB": 1.1788943500104991, "GILENYA": 1.616807442400913, "HALAVEN": 1.2816193858332934, "HUMIRA": 1.8564263974331912, "ICLUSIG": 1.3515211022238656, "INLYTA": 1.05186547316671, "INTERFERON": 1.42792357080656, "INVIRASE": 2.0586104908299965, "IRESSA": 1.670610099451444, "ISCOVER": 3.237199686355869, "ISENTRESS": 1.8682285331231736, "KAFTRIO": 3.790087792149658, "KALETRA": 1.361220695278791, "KALYDECO": 2.1111001056381147, "KEPPRA": 1.3974004482915223, "KETEK": 4.112390649915261, "KEYTRUDA": 1.21682672616858, "KISQALI": 5.272050677932922, "LAMIVUDINE": 1.3149092392581758, "LEFLUNOMIDE": 4.739553704481245, "LEVOFLOXACIN": 1.4567162481598577, "LUMYKRAS": 7.465820312607308, "LYSODREN": 5.57478748706496, "MAVENCLAD": 1.2735695725918277, "MEKINIST": 1.7574664222562482, "MERCAPTOPURINE": 1.0674738583076715, "METHOTREXATE": 2.4627770087137715, "MULTAQ": 4.548486744941788, "MYCAMINE": 7.11490876436069, "NALOXONE": 1.945862736351585, "NILOTINIB": 1.233758896865218, "NORVIR": 3.0386557845788955, "NOVONORM": 1.580081861821157, "NOXAFIL": 3.214384020088055, "OCALIVA": 2.8243513908082805, "OFEV": 5.231652055886028, "OLANZAPINE": 1.3855081943477054, "OLYSIO": 1.536477394462751, "OPDIVO": 1.2437694159239792, "ORENCIA": 7.180405049501145, "ORKAMBI": 2.7717948960003884, "OXYBUTYNIN": 1.0009761159948083, "PANTOPRAZOLE": 1.5657251086509616, "PAZOPANIB": 1.7110271154789958, "PIOGLITAZONE": 2.19872677036686, "POSACONAZOLE": 1.5453193930114797, "PREZISTA": 6.63038261211724, "PROTELOS": 1.7841060013776615, "RAPAMUNE": 1.047588175552009, "RASILEZ": 1.1582915697411285, "REBIF": 7.643155245745204, "REMDESIVIR": 9.633870317623938, "REYATAZ": 1.546394765821265, "RIBOCICLIB": 2.888928198072392, "RILUTEK": 2.8071925575445054, "RINVOQ": 1.2257264817834037, "RISPERIDONE": 1.2363228502375905, "RITUXIMAB": 1.6180344354268077, "ROACTEMRA": 1.069682234969291, "RUBRACA": 1.788766499921065, "SAXENDA": 1.2630587266673616, "SOTORASIB": 5.34836961827246, "STIVARGA": 1.3754107961096669, "SUBOXONE": 1.2998457951182834, "TAMIFLU": 1.3886919470114274, "TASIGNA": 1.671647304216213, "TEMODAL": 1.488274741387215, "TERIFLUNOMIDE": 3.7271520613998126, "THIOTEPA": 1.467023201217323, "TIVICAY": 1.544358061375591, "TOCILIZUMAB": 1.0008949519929675, "TRACLEER": 2.367329622969917, "TREMFYA": 1.9520315096718728, "TRIUMEQ": 1.8358195915194435, "TWINRIX": 4.959237176846464, "TYGACIL": 7.505495467581143, "VEKLURY": 4.216169567130054, "VFEND": 4.599830115668609, "VIRAMUNE": 5.354667022882833, "VORICONAZOLE": 5.125327474188579, "VOTRIENT": 5.789879291856269, "XALKORI": 3.6045794617790343, "XELJANZ": 1.0771706962327865, "YERVOY": 1.77496020560525, "YONDELIS": 3.4749654815084074, "ZELBORAF": 1.1063296781418606, "ZIAGEN": 1.5975330365072848, "ZYPREXA": 2.8548741222927885, "null": 1.082105678969637}
\ No newline at end of file
+{"BYDUREON": 27.78662041303839, "FIASP": 77.41934660973901, "SAXENDA": 10.475156925010918, "SIMPONI": 9.252499300849657, "null": 5.120045429762028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3778.json
index c0be9fac658..3fbd5d5f136 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3778.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3778.json
@@ -1 +1 @@
-{"ACTOS": 3.316929287405668, "AFINITOR": 1.6105017536053536, "ALEMTUZUMAB": 1.2991424827036524, "ALIMTA": 1.245986316987159, "AMINOSALICYLIC": 1.281836193680547, "ASPARAGINASE": 2.305920437185893, "ATAZANAVIR": 1.1861355774044142, "AVANDAMET": 1.7347803489390954, "AVANDIA": 3.236832711774552, "AVASTIN": 1.3502882695553928, "AZACITIDINE": 2.084752138218937, "BARACLUDE": 8.603040182070085, "BEVACIZUMAB": 2.0145230023383824, "BIKTARVY": 1.252996202748378, "BOCEPREVIR": 5.513339956177235, "BRAFTOVI": 1.060170714021598, "BUSULFAN": 3.617915090601779, "CABOMETYX": 1.2063659732060985, "CANCIDAS": 7.318640578884482, "CAPECITABINE": 1.9193906316424, "CASPOFUNGIN": 3.873910618107945, "CELLCEPT": 1.8105599398292624, "CICLOSPORIN": 2.2974582072651035, "COMBIVIR": 2.803573999074436, "CRIXIVAN": 3.5695366402112723, "CUBICIN": 1.8634700795026395, "CYMBALTA": 1.0574253701561374, "CYTARABINE": 1.9433480964564775, "DACLATASVIR": 14.654868112645074, "DAKLINZA": 3.512925606790343, "DEFITELIO": 7.872684492667658, "DELAMANID": 3.441675655874743, "DEXAMETHASONE": 1.1254777245199812, "DOXORUBICIN": 2.812731149240664, "DULOXETINE": 2.013705429251732, "EFAVIRENZ": 3.505591031160231, "ENTECAVIR": 5.241794303683563, "ENTRESTO": 1.393705231169816, "EPCLUSA": 9.257989010077388, "EPIVIR": 5.158185731886874, "EXJADE": 4.514250262162161, "EXVIERA": 28.82156358633786, "FASLODEX": 3.258113086575281, "FEBUXOSTAT": 3.566373352290183, "FILGRASTIM": 1.2284809290964869, "FULVESTRANT": 2.0136392652279995, "GLIVEC": 1.5049086666881104, "HALAVEN": 3.975270799516212, "HARVONI": 8.15056300473802, "HEPSERA": 3.7644806714094976, "HERCEPTIN": 1.4187602913877515, "IBUPROFEN": 2.559207143884576, "ICLUSIG": 2.4449472374071406, "INCIVO": 3.059422955011196, "INTERFERON": 5.082185707007766, "INTRONA": 4.221086457258415, "INVIRASE": 8.932145023673755, "IRBESARTAN": 2.7390226056209133, "IRINOTECAN": 1.4255292456778976, "ISENTRESS": 3.980495514478459, "JANUVIA": 1.5996946060372064, "JEVTANA": 1.5086829622481537, "KAFTRIO": 2.106941850169829, "KALETRA": 2.8120481449211856, "KEPPRA": 2.011918240376368, "KEYTRUDA": 1.7315825261021522, "KISQALI": 1.0155450525331302, "KYMRIAH": 1.4113945167146835, "LAMIVUDINE": 8.14290679146103, "LENVIMA": 8.739479561409487, "LEVOFLOXACIN": 1.0508520461175304, "LONSURF": 3.0403359611977687, "LUTATHERA": 3.095572143425118, "LYNPARZA": 1.1367282989733456, "MABTHERA": 2.262710952945633, "MEKINIST": 1.3246377532492792, "METHOTREXATE": 1.1155935855450445, "MICAFUNGIN": 11.50809851459593, "MIDAZOLAM": 1.1883439147594603, "MULTAQ": 5.437816619526552, "NEXAVAR": 11.48919229175478, "NORVIR": 1.863474453130562, "NOVOSEVEN": 3.888384459819625, "NOXAFIL": 3.2106361777137837, "NPLATE": 1.4498792687074873, "OCALIVA": 27.502509529277027, "OLYSIO": 18.711822179841597, "ONCASPAR": 2.808892939856285, "OPDIVO": 2.0937343647489457, "PACLITAXEL": 1.4440287173194015, "PAZOPANIB": 2.9361488499410715, "PEGASYS": 3.443414651590041, "PEGINTERFERON": 5.390482336424336, "PEGINTRON": 2.241652016966446, "PLAVIX": 1.3308928651914758, "RAPAMUNE": 1.3219605931431, "REBETOL": 2.507551801256786, "REVATIO": 1.297501352464702, "RIBAVIRIN": 7.293326038199944, "RIBOCICLIB": 3.4202275596948484, "RITUXIMAB": 1.9095858024172236, "SIMEPREVIR": 7.729320461372979, "SOLIRIS": 1.684186709412586, "SORAFENIB": 6.0591430036270655, "SOVALDI": 5.931417114939051, "SPIRONOLACTONE": 1.4593645731435176, "STIVARGA": 8.636632298966086, "SUBOXONE": 1.4315319419395285, "SUTENT": 1.740250237353605, "TACROLIMUS": 1.7942144565459317, "TAMIFLU": 2.8418831689433293, "TEMODAL": 1.682266006767373, "TEMOZOLOMIDE": 2.3241201067759727, "TIVICAY": 2.2570005405403166, "TRACLEER": 2.4393427003107444, "TRODELVY": 1.7418776448955116, "VFEND": 3.494106102942393, "VIRAMUNE": 16.531134540057057, "VIREAD": 2.6300231830330025, "VORICONAZOLE": 2.309191565203176, "VOTRIENT": 4.045896300434097, "XALKORI": 3.4069040832345747, "XELODA": 1.3310947516092178, "YERVOY": 4.671356820221756, "YONDELIS": 11.40502088599487, "ZELBORAF": 1.8027953225513305, "null": 1.3748606635679952}
\ No newline at end of file
+{"BETAFERON": 9.141797321708395, "BUPIVACAINE": 8.13560407858307, "BYDUREON": 5.529588573805418, "METHOTREXATE": 1.5643390288341854, "NEULASTA": 3.022838220860692, "PLEGRIDY": 607.3147797123646, "ROACTEMRA": 4.03292969688447, "SIMPONI": 287.08708841068693, "STELARA": 4.514727077496095, "TREMFYA": 45.03986657516173, "null": 0.3335052349043884}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3779.json
index aed51433a22..b6d7901aac9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3779.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3779.json
@@ -1 +1 @@
-{"ARAVA": 2.2515180600756315, "ARIPIPRAZOLE": 4.629840248078052, "AZATHIOPRINE": 7.556311397360255, "CICLOSPORIN": 12.088102766815824, "COMBIVIR": 8.088944048381823, "ENBREL": 10.122942352231377, "EXJADE": 4.473366987393571, "HUMIRA": 3.169660866236496, "METHOTREXATE": 3.11179458827036, "OCALIVA": 79.48418554905066, "PEGASYS": 4.754606118452727, "PEGINTRON": 3.994828936692246, "RIBAVIRIN": 8.477722510818781, "SOVALDI": 12.041285487330828}
\ No newline at end of file
+{"BUPRENORPHINE": 68.43012578350323, "null": 4.567039029815741}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/378.json
index 730ce765cd4..5e0087ec5ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/378.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/378.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.9785651676674956, "AVASTIN": 14.96573745781695, "CABOMETYX": 7.979772157139022, "CIMZIA": 7.458681341348496, "ENTYVIO": 37.930542835594586, "HUMIRA": 26.707534798010467, "NEXAVAR": 3.8626713946848215, "SIMPONI": 5.600153393094922, "STELARA": 31.5891877218104, "STIVARGA": 6.595486222015647, "SUTENT": 4.899021518653251}
\ No newline at end of file
+{"ABILIFY": 0.7052362846345431, "ACTRAPID": 1.979412821377983, "ADENURIC": 5.865438592296768, "ADVAGRAF": 6.929416770805925, "AERIUS": 1.872852550094844, "ALIMTA": 1.7062092893896377, "AMIKACIN": 1.3793893226995522, "APROVEL": 2.004319071571178, "ARANESP": 0.4545047255910974, "ARAVA": 0.1523830249490891, "ARIPIPRAZOLE": 1.9093253743590484, "ASPARAGINASE": 1.4116944706917915, "AVASTIN": 0.9058996033597648, "AZACITIDINE": 3.956415070085957, "BENLYSTA": 0.2790977027092075, "BEVACIZUMAB": 0.4508645969101759, "BIKTARVY": 0.4649649675201709, "BORTEZOMIB": 1.8027371456653367, "BRILIQUE": 0.3526238231143551, "BUSULFAN": 1.1412817359408418, "CAELYX": 1.5547548518482766, "CANCIDAS": 5.870420614198936, "CAPECITABINE": 0.6520623231072464, "CARMUSTINE": 1.6211942845451417, "CASPOFUNGIN": 1.4025245603625616, "CELLCEPT": 11.052720005782469, "CICLOSPORIN": 0.5161017579046443, "CIRCADIN": 4.245743534894539, "CLADRIBINE": 2.229961320590616, "CLOPIDOGREL": 1.0246838034406422, "COAPROVEL": 2.2017441041641512, "COMBIVIR": 1.063593523471496, "COMIRNATY": 0.0093856744131899, "CUBICIN": 1.797662580027471, "CYMBALTA": 0.0821733041247711, "CYTARABINE": 2.4646868362278846, "DEXAMETHASONE": 1.487593168565314, "DIFICLIR": 7.199926436183636, "DOCETAXEL": 10.3036632236459, "DOXORUBICIN": 8.878035913894303, "ELIQUIS": 0.4711259248043756, "EMEND": 1.2758423381695887, "EPIVIR": 0.877373788779316, "ERLEADA": 2.359840747130188, "ESOMEPRAZOLE": 2.298432727642905, "EXFORGE": 0.2648262267318486, "EXJADE": 0.202668540015827, "FASLODEX": 0.283466627119145, "FEBUXOSTAT": 1.688375664029723, "FILGRASTIM": 6.656439416068348, "FORXIGA": 0.3096998038096563, "GANCICLOVIR": 4.13365249352052, "GAZYVARO": 4.248517937858285, "HALAVEN": 0.848327383224413, "HERCEPTIN": 1.2741535546979186, "HYCAMTIN": 2.2458824067425622, "HYDROCORTISONE": 0.750720401171829, "IBRANCE": 0.2116358357382535, "IBUPROFEN": 3.0137154871918246, "IMBRUVICA": 1.5733263744765795, "INCIVO": 0.4243298850623394, "INTRONA": 1.0688917036705678, "IPILIMUMAB": 0.8439490551643833, "IRBESARTAN": 1.0184123656810455, "IRINOTECAN": 1.001644289263253, "ISENTRESS": 0.6888660348756492, "JAKAVI": 0.5391385371254352, "JANUVIA": 0.3282201425225187, "JARDIANCE": 0.0884145650854521, "JEVTANA": 1.3774970841878869, "KALETRA": 0.7539258381118509, "KEPPRA": 3.04553555914662, "KESIMPTA": 1.252132772681713, "KEYTRUDA": 0.653974583541205, "KINERET": 15.808854883498803, "KYMRIAH": 1.1138862729744792, "LEMTRADA": 0.4306030708538074, "LEVETIRACETAM": 1.713585657006084, "LEVOFLOXACIN": 1.2701699489646543, "LYRICA": 1.2274004829330885, "MABCAMPATH": 5.171829540164675, "MABTHERA": 21.35592202430412, "MEKINIST": 0.23843128775984, "MELPHALAN": 1.8297500064163823, "MERCAPTOPURINE": 4.247945710048274, "METHOTREXATE": 2.035102244476457, "MICARDIS": 0.6142477833379199, "MYCOPHENOLATE": 0.7269955275321403, "NEULASTA": 0.8564777540968506, "NEXAVAR": 0.138059835238827, "NORVIR": 1.724777550320212, "NOT": 0.6663510195944585, "OBINUTUZUMAB": 1.8907737336122816, "OLANZAPINE": 2.334362137864789, "OPDIVO": 0.749445108492784, "PACLITAXEL": 5.400041867307678, "PANTOPRAZOLE": 2.910360593664317, "PEGASPARGASE": 13.683229995519577, "PEGASYS": 0.3667430818719913, "PEGFILGRASTIM": 2.809958748333007, "PEGINTERFERON": 0.9892671380562488, "PEGINTRON": 0.988323040336132, "PEMBROLIZUMAB": 1.1417018307762037, "PEMETREXED": 1.4471252957970564, "PLAVIX": 4.914041204414626, "PREGABALIN": 0.9986740412986972, "PROPRANOLOL": 1.7259968030067814, "RIBAVIRIN": 0.7998326523892947, "RILUTEK": 7.717355657915041, "RITUXIMAB": 5.446476363809668, "RIXATHON": 10.16501930291214, "ROACTEMRA": 1.4378093900976394, "SIMPONI": 0.1036938955343127, "SOLIRIS": 0.3123231908555295, "SPRYCEL": 0.4049003452925231, "SUTENT": 0.068298148769457, "TAMIFLU": 1.3038962950811628, "TASIGNA": 0.276775729081088, "TAXOTERE": 32.64999280948443, "TEMODAL": 6.890720876523194, "TEMOZOLOMIDE": 1.47496800116783, "THALIDOMIDE": 1.2962426939478786, "TRODELVY": 0.9666976985673484, "VAXZEVRIA": 0.0052601078859277, "VENETOCLAX": 3.4474401026453334, "VFEND": 2.820135410799613, "VIMPAT": 2.426673470568219, "VORICONAZOLE": 1.3015315512965766, "XARELTO": 1.29815629587975, "XELODA": 1.9832377627022972, "YESCARTA": 0.9979967247817312, "ZYPREXA": 1.4622845144148342, "null": 4.923566921729926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3780.json
index 87af7f90c50..078c12ea59e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3780.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3780.json
@@ -1 +1 @@
-{"ACTOS": 3.044585180215502, "ACTRAPID": 1.565891883625952, "ADCETRIS": 1.900223480657396, "ADCIRCA": 1.5473313440807073, "ADEFOVIR": 3.9970933837906446, "AFINITOR": 1.0081634941440938, "ALIMTA": 1.2807358586020796, "ALL": 1.3098526367469814, "AMIKACIN": 2.051119123426317, "ARIXTRA": 1.5144532993222102, "ASPARAGINASE": 1.2077744969888262, "ATAZANAVIR": 1.4530278020563276, "AVASTIN": 1.6008407509088822, "AXITINIB": 4.788479524448436, "AZTREONAM": 2.050770917060521, "BARACLUDE": 2.002145938159553, "BAVENCIO": 5.424957449979547, "BETAFERON": 1.8437835577979365, "BEVACIZUMAB": 1.4362347282672023, "BOSULIF": 3.0662561213551527, "BOSUTINIB": 2.0651031824490067, "BRAFTOVI": 1.9418433814947216, "CABOMETYX": 7.711501273654812, "CANCIDAS": 8.582483043645569, "CAPECITABINE": 1.4821642379312516, "CASPOFUNGIN": 2.3528226303033843, "CEFUROXIME": 12.85936133982243, "CELECOXIB": 1.824060866456276, "CELLCEPT": 1.5766783287716182, "CICLOSPORIN": 1.6034347323557454, "CLOPIDOGREL": 1.502676409021357, "COMBIVIR": 1.4562056481531636, "COMPLEMENT": 9.63094524108071, "CRIXIVAN": 2.962430665363821, "CUBICIN": 1.919980357807272, "CYTARABINE": 1.6166793733934155, "DACLATASVIR": 1.600537705331104, "DELTYBA": 7.170335901092754, "DESCOVY": 1.1041072775159666, "DEXRAZOXANE": 15.457328056668027, "DOCETAXEL": 3.646807882703908, "DOXORUBICIN": 3.703434639682866, "DYNASTAT": 71.56504306676347, "EFAVIRENZ": 1.611298802973331, "EFIENT": 1.5582034525920443, "EMEND": 2.0429653074061216, "EMTRICITABINE": 2.8756629219362466, "ENOXAPARIN": 4.58146862287175, "ENTECAVIR": 3.891896903411976, "EPIRUBICIN": 8.258949751227288, "EPIVIR": 3.12602261018401, "ERBITUX": 1.6672442703019543, "ERIBULIN": 3.96687279735733, "EVISTA": 1.0533391217724184, "EXJADE": 1.2684146439562651, "FEBUXOSTAT": 10.761300746992374, "FYCOMPA": 1.0976556367375214, "GANCICLOVIR": 3.481567379843093, "GEFITINIB": 6.852372897748949, "GLIBENCLAMIDE": 1.3163391594803604, "GLIVEC": 1.525401356677778, "HALAVEN": 3.643069809509709, "HEPSERA": 1.854142514741099, "HERCEPTIN": 2.030584157575595, "HUMAN": 1.221683630055291, "HYDROCHLOROTHIAZIDE": 1.4593757729326278, "IBUPROFEN": 1.2361410040144318, "ICLUSIG": 1.6691939898247783, "INDINAVIR": 5.055162197363615, "INLYTA": 1.8047060481457664, "INTRONA": 1.663523993988918, "IRESSA": 17.140323775773716, "JANUVIA": 1.487745124376113, "JEVTANA": 1.3318638229032946, "KEYTRUDA": 4.693811020261388, "KYPROLIS": 1.9745921764520744, "LAMIVUDINE": 2.688355880050378, "LENVIMA": 5.5269270061868045, "LEVETIRACETAM": 1.0203272274570607, "LEVOFLOXACIN": 4.947155426804847, "LUTATHERA": 1.1648443393941774, "LYNPARZA": 1.170346799549405, "MABTHERA": 1.8872291163816588, "MANNITOL": 5.592244400988305, "MEKINIST": 1.7839205872499249, "MERCAPTOPURINE": 2.0764371786360987, "METFORMIN": 2.63039415612761, "METHOTREXATE": 1.6441346199111355, "MICAFUNGIN": 9.703154620030972, "MICARDIS": 6.410125701386251, "MIRCERA": 1.4504244833981117, "MIXTARD": 1.834392063259952, "MYCAMINE": 3.0241408115384925, "NEXAVAR": 8.49895943130735, "NOT": 2.731961783495609, "NOVONORM": 2.599755096988864, "NOXAFIL": 2.9074267306114456, "NUBEQA": 6.281596871720396, "OBINUTUZUMAB": 1.012009710008423, "OFEV": 1.1830515540149684, "OLANZAPINE": 3.748057436574508, "OLOPATADINE": 20.77731600369258, "OLYSIO": 2.22619695749173, "OPDIVO": 8.778091511202947, "PACLITAXEL": 4.07166048630619, "PAZOPANIB": 5.457018408316558, "PEGASPARGASE": 2.9499715632230257, "PEMETREXED": 4.0343043886864685, "PERTUZUMAB": 1.981486182533908, "PLAVIX": 2.2849152445377507, "REMICADE": 1.2885630368894014, "SAMSCA": 12.598073836728853, "SILODOSIN": 8.72391390976674, "SIMEPREVIR": 2.908375892489848, "SIRTURO": 4.097208895425196, "SORAFENIB": 1.2031698680694014, "SOTORASIB": 9.268010685628123, "SOVALDI": 1.2273788440819893, "SPIRONOLACTONE": 1.817912731742393, "STIVARGA": 10.63835845570408, "STOCRIN": 6.044500916883304, "SUTENT": 1.143364562525633, "TACROLIMUS": 1.4305664461909435, "TAGRISSO": 2.429688221568133, "TAMIFLU": 7.081140197926548, "TASIGNA": 1.712926133459509, "TAXOTERE": 2.8702610770476173, "TEMODAL": 4.416454579961031, "TEMOZOLOMIDE": 1.224476763191964, "TIGECYCLINE": 6.831461780872209, "TRACLEER": 1.2233793540100666, "VALSARTAN": 2.728084937821881, "VEKLURY": 8.918923321155901, "VEMLIDY": 3.19438945838244, "VFEND": 14.997091955294549, "VILDAGLIPTIN": 2.248476036411119, "VIMPAT": 1.2614205299819243, "VIRAMUNE": 1.2576968391601513, "VORICONAZOLE": 10.931019075800709, "VOTRIENT": 2.362625784607744, "XALKORI": 5.255674747529746, "XELODA": 6.779865604880881, "YONDELIS": 3.702116887134036, "ZONISAMIDE": 2.6465515709358494, "ZYPREXA": 1.614449149316158, "null": 2.51863494617491}
\ No newline at end of file
+{"ABILIFY": 0.5469913515372387, "ACETAMINOPHEN/OXYCODONE": 197.37695047392972, "ADALIMUMAB": 0.1111243213678758, "ANAKINRA": 0.5283067044642851, "ANTIDEPRESSANTS": 17.39829051045501, "APIDRA": 0.1559009664557388, "ARAVA": 0.070392034931434, "ARIPIPRAZOLE": 2.3609778252611844, "ATRIPLA": 0.0123597777678487, "AVAMYS": 0.4960130794279226, "AZATHIOPRINE": 1.0775811812095872, "BENZODIAZEPINE": 9.552223164224207, "BENZODIAZEPINES": 4.937416434744581, "BOSULIF": 0.5469153531258577, "BRINTELLIX": 0.1739708423041064, "BUDESONIDE": 0.6532948922015175, "BUMETANIDE": 2.483385532904476, "BUPIVACAINE": 0.7561426229190055, "BUPRENORPHINE": 86.06992509283438, "BUVIDAL": 4.887444626431577, "CAFFEINE": 6.506951319547394, "CANNABIDIOL": 6.837390555835788, "CHAMPIX": 0.7490409716417852, "CIMZIA": 0.0446218949296313, "COMTAN": 0.9310288770224502, "CYMBALTA": 0.6231974547785568, "DENOSUMAB": 1.6250584903266867, "DULOXETINE": 1.660993525646301, "ENBREL": 1.788524419666852, "ENTYVIO": 0.4502593981459046, "EXFORGE": 0.1936335372321777, "FENTANYL": 11.883145915379536, "HUMAN": 0.6164671286614191, "HUMIRA": 0.7511498061776755, "HYDROCORTISONE": 0.3125275303313449, "IBRANCE": 0.1162890900625041, "IBUPROFEN": 0.9631762882298128, "INFLIXIMAB": 0.8971366821661578, "IRBESARTAN": 0.5562175523395135, "KEPPRA": 0.3163342848683456, "LANTUS": 0.1218850746932493, "LATUDA": 0.3374840520990421, "LEVETIRACETAM": 0.1528214430464452, "LEVODOPA": 3.5291502802900347, "LYRICA": 4.188221714357229, "MELATONIN": 0.5223653951266559, "MEPOLIZUMAB": 0.7497321935941013, "METHOTREXATE": 0.1845839508963088, "MIDAZOLAM": 1.9280054074059303, "NALOXONE": 2.240456040552168, "NOT": 0.7466980974564806, "NUCALA": 0.442139049046482, "OLANZAPINE": 0.5147521503382411, "OMALIZUMAB": 0.8225804945444813, "OPIOIDS": 30.465534988836197, "PEGASYS": 0.0667069731628026, "PEGINTRON": 0.3687308123607979, "POPPERS": 7.356793977485433, "PREGABALIN": 6.743504180195513, "RELVAR": 0.4436247636769718, "RISPERIDONE": 1.423547357429495, "SIFROL": 1.2038729384468754, "SPIRONOLACTONE": 1.4889423459811928, "STALEVO": 0.8985309516430057, "SUBOXONE": 19.691327967674003, "SUBSTANCE": 7.616059680106968, "TOVIAZ": 1.4356397620329713, "VIAGRA": 1.5813359647657692, "XELJANZ": 0.4166418405383499, "XYREM": 0.6890809389506887, "ZOSTAVAX": 0.1093703364074516, "ZYPREXA": 0.3388252777829835, "null": 5.888500093523498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3781.json
index 4654b5e2cb7..b9b7249ed4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3781.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3781.json
@@ -1 +1 @@
-{"ARAVA": 6.094181489152541, "null": 1.0977600735173605}
\ No newline at end of file
+{"null": 2.653709282728216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3782.json
index ee697fa4f82..26b6873e9e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3782.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3782.json
@@ -1 +1 @@
-{"ELIQUIS": 7.110144150968395}
\ No newline at end of file
+{"BENZODIAZEPINE": 50.371841410850855, "BUPRENORPHINE": 62.705382163006256, "FENTANYL": 24.89531289086316, "SUBOXONE": 391.71877846177904, "null": 0.891561356156262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3783.json
index 2dfbae69331..17a96698722 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3783.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3783.json
@@ -1 +1 @@
-{"NEXAVAR": 30.31547483983686}
\ No newline at end of file
+{"DAPTOMYCIN": 1786.848880883941, "null": 1.3527770936992607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3784.json
index 612903f82a8..f9d28c6f915 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3784.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3784.json
@@ -1 +1 @@
-{"SUTENT": 3.936252130158774}
\ No newline at end of file
+{"BUPRENORPHINE": 28.686060335756373, "FENTANYL": 16.690441906471303, "LYRICA": 5.608239767139101, "MIDAZOLAM": 7.725627508358282, "PREGABALIN": 8.117969408865223, "SAXENDA": 7.625587751494669, "SUBOXONE": 58.925001048524685, "null": 4.186464286089268}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3785.json
index b34927d8ab6..7630400af4f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3785.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3785.json
@@ -1 +1 @@
-{"null": 1.008089787236376}
\ No newline at end of file
+{"AIMOVIG": 77.35046358687033, "APIDRA": 5.867084425452588, "ARANESP": 4.724573211294067, "BIRESP": 1047.2784940604204, "BYDUREON": 12.550878171687204, "COSENTYX": 6.133042607560538, "FASENRA": 40.192298853426415, "LANTUS": 3.3366776509454046, "NEULASTA": 26.08128750248776, "PLEGRIDY": 80.53672255380215, "TOUJEO": 11.456468695840517, "null": 2.405761392166851}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3786.json
index 28dab320152..9e5a797ce79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3786.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3786.json
@@ -1 +1 @@
-{"ABRAXANE": 55.30702437836333, "ADENURIC": 16.33422370365732, "AFINITOR": 19.424493777696824, "ALPELISIB": 36.89639442563308, "APIXABAN": 6.406212220377328, "ASPARAGINASE": 4.453349404255383, "AVASTIN": 3.229967050805918, "BYETTA": 6.904393071905728, "CAPECITABINE": 10.802799056407746, "CICLOSPORIN": 2.170405411874695, "COSENTYX": 1.0858052720362146, "CYTARABINE": 3.3495688838688578, "DOCETAXEL": 4.084418921600537, "EVEROLIMUS": 13.903296751737496, "EXVIERA": 14.322785173136614, "FASLODEX": 8.233547579008386, "FULVESTRANT": 9.348119059420426, "HARVONI": 5.663877675850996, "IBRANCE": 2.000698295339397, "IPILIMUMAB": 4.6931242684799095, "JANUMET": 13.960536625289276, "JANUVIA": 9.830982992202497, "KALETRA": 4.611709795982127, "KEYTRUDA": 1.1115602769851556, "KISQALI": 8.380137348698895, "MEKINIST": 3.5467034862827203, "NEXAVAR": 14.791776052853082, "OLYSIO": 8.933914118091076, "RIBAVIRIN": 5.493003906844376, "RIBOCICLIB": 24.1811488612435, "SUTENT": 1.2576882310880142, "VOTRIENT": 2.4030685492749413, "XELODA": 9.691426315849826}
\ No newline at end of file
+{"IBUPROFEN": 12.809088712565975, "REAGILA": 523.1307302031682, "SAXENDA": 77.11765511333691, "VICTOZA": 85.72050024650936, "null": 1.2548186883382246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3787.json
index a698a1966f2..2652ad31f79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3787.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3787.json
@@ -1 +1 @@
-{"AFINITOR": 9.544977231954917, "BYETTA": 12.024211637252533, "CICLOSPORIN": 2.709496112152312, "DEXAMETHASONE": 3.6865592018792928, "EVEROLIMUS": 29.730763792722183, "HARVONI": 20.32763330193152, "JANUMET": 4.922105956492443, "JANUVIA": 10.065711819156355, "KEYTRUDA": 1.9539175531173627, "NEXAVAR": 7.88935457435623, "PEGASYS": 3.794014914531565, "PEGINTRON": 3.5459208449778123, "STIVARGA": 5.137931716152903}
\ No newline at end of file
+{"null": 0.9728078020631838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3788.json
index 7b0cefe6d4d..2fd00762b65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3788.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3788.json
@@ -1 +1 @@
-{"ABACAVIR": 2.747350681839932, "AVANDIA": 3.435162665874572, "BUDESONIDE": 1.4816522176607971, "BUSULFAN": 9.069035468308886, "CICLOSPORIN": 3.517173853175943, "FENTANYL": 1.9778639613367064, "IBUPROFEN": 6.66729557090834, "NEXAVAR": 2.176164379130741, "PEGINTRON": 1.2517607510245017, "SOMATROPIN": 118.82859525466692, "VIRAMUNE": 25.42466373157117, "null": 2.6082047638926658}
\ No newline at end of file
+{"AIMOVIG": 3.6687031550867, "BENLYSTA": 4.850461765358749, "BUPRENORPHINE": 5.534361664045555, "CIALIS": 45.5102683415831, "COSENTYX": 3.036140445235973, "ENTYVIO": 18.341086226131743, "EVENITY": 11.829188906857402, "FASENRA": 13.253040158480458, "FESOTERODINE": 154.80469089025684, "NOVORAPID": 6.994479310933891, "PREGABALIN": 8.085496973990145, "SAXENDA": 13.47457734922356, "SUBOXONE": 12.662211326013413, "XELJANZ": 2.338231281856028, "null": 1.6070222759816573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3789.json
index 8ee688ac3f4..78380707050 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3789.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3789.json
@@ -1 +1 @@
-{"AFINITOR": 10.010872653601751, "CICLOSPORIN": 1.995144572370676, "DAKLINZA": 33.68786281065437, "FASLODEX": 12.644570116089673, "LANTUS": 4.419910209243774, "NEXAVAR": 4.138244583619787, "PEGASYS": 3.3080952244922788, "PEGINTRON": 3.539833829639244, "SUTENT": 1.576370232054771, "VOTRIENT": 5.737294089541829, "null": 1.1986082806035194}
\ No newline at end of file
+{"ABILIFY": 4.499781009604421, "ARIPIPRAZOLE": 2.251145300884542, "HUMAN": 131.17409318499827, "IBRANCE": 1.599558490588373, "KEYTRUDA": 4.970677027113952, "LACOSAMIDE": 9.19346987839598, "LATUDA": 9.497261143728627, "LEVETIRACETAM": 2.6453370919791683, "LOPINAVIR": 23.32659153443981, "MELATONIN": 18.292379266965742, "NUCALA": 2.2230263346291266, "PEMBROLIZUMAB": 15.53391670002147, "RAPAMUNE": 12.74091358563846, "RELVAR": 8.4967692179955, "RITUXIMAB": 2.856164072581936, "VIAGRA": 5.650401654667255, "XELJANZ": 13.77570587592441, "null": 1.8605063215028723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/379.json
index 097dfb6ca5f..08f81943bd7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/379.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/379.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 3.8157259600014415, "ELIQUIS": 10.029547541584476, "INCIVO": 13.15985497548179, "LIXIANA": 21.132663684390533, "PEGASYS": 2.6022841428211843, "PEGINTERFERON": 6.423823976199437, "PLAVIX": 1.57283760957711, "SUTENT": 8.00869605571562}
\ No newline at end of file
+{"null": 0.7945367150999303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3790.json
index 1376402afad..317f6c0ae7e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3790.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3790.json
@@ -1 +1 @@
-{"AFINITOR": 2.6467467875753243, "FORSTEO": 1.6008848803566416, "HARVONI": 5.623214282279865, "NEXAVAR": 1.0337598617673276, "OZEMPIC": 55.69969086080869, "PANTOPRAZOLE": 3.810240650192357, "PEGASYS": 8.362370050043396, "PEGINTERFERON": 3.140197980507461, "PEGINTRON": 4.081818816527785, "SUBOXONE": 3.45016794808575, "SUTENT": 1.3062295969657092, "XELJANZ": 1.1632330950329886, "null": 1.023700388114421}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3791.json
index a079472af77..73780dbe470 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3791.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3791.json
@@ -1 +1 @@
-{"NEXAVAR": 77.29630421893182}
\ No newline at end of file
+{"ALEMTUZUMAB": 16.5761617437518, "FILGRASTIM": 323.0463228627666, "GARDASIL": 5.386528222966223, "LEMTRADA": 93.81755849920506, "PEGINTRON": 8.69825360655664, "STELARA": 4.089502772365296, "null": 0.9859129515498816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3792.json
index 522be4f4780..19e59268b56 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3792.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3792.json
@@ -1 +1 @@
-{"ABACAVIR": 1.4732873098198551, "ABILIFY": 1.296031125963983, "ACTOS": 4.236753654067889, "ACTRAPID": 4.572345449220898, "AFINITOR": 1.1210284442002312, "ARAVA": 2.3329643479107456, "ARZERRA": 17.234922817130382, "ASPARAGINASE": 9.348567678525148, "AUBAGIO": 1.4349919862256415, "AVANDIA": 1.4184724873190682, "AVASTIN": 2.39125510912377, "BEDAQUILINE": 1.6985356855811466, "BETAFERON": 3.333658828091606, "BEVACIZUMAB": 2.275603479062707, "BIKTARVY": 4.072503965535388, "BYDUREON": 3.1533730983327506, "BYETTA": 9.350644960948664, "CARFILZOMIB": 3.226085907701021, "CELECOXIB": 3.020415781021836, "CICLOSPORIN": 1.0148744543062356, "CIMZIA": 1.2886509321946111, "CLOPIDOGREL": 1.0370798814638906, "COMBIVIR": 5.560928095815048, "COSENTYX": 3.1343212748256826, "CRIXIVAN": 8.871254499605044, "CYMBALTA": 2.66791333686823, "CYTARABINE": 2.2874937092487726, "DULOXETINE": 3.285390202804205, "EFAVIRENZ": 2.7406433723046995, "ENBREL": 1.6805052862928551, "ENFUVIRTIDE": 24.90715761283308, "ENTYVIO": 1.3892827683118512, "EPIVIR": 12.599659604994558, "ESMYA": 7.925074418281881, "EUCREAS": 5.053654039446934, "EXFORGE": 1.630575086726732, "FASLODEX": 1.1640353888582422, "FORXIGA": 1.8627198406666423, "GALVUS": 9.965332850329574, "HEPSERA": 4.225463456311646, "HUMIRA": 3.389562218203732, "IBUPROFEN": 2.028187761763912, "INSULIN": 1.643358759633678, "JANUMET": 8.214726459942288, "JANUVIA": 5.413213356394599, "JARDIANCE": 1.1693253096801126, "KAFTRIO": 1.8019524067152544, "KALETRA": 1.612274592972926, "LAMIVUDINE": 4.955490336452736, "METFORMIN": 16.351750291338135, "METHOTREXATE": 4.71717751563075, "NORVIR": 5.292626917247405, "OLANZAPINE": 2.371827513534692, "ONCASPAR": 8.173486909472942, "PANTOPRAZOLE": 2.08926869072572, "PEGASYS": 1.5572717891602583, "PEGINTERFERON": 1.313463109953762, "PREGABALIN": 3.58156528209786, "REYATAZ": 3.8311509001919695, "RIBOCICLIB": 3.3403508294835342, "RINVOQ": 1.1469280622694509, "RITUXIMAB": 1.0154980225161865, "ROACTEMRA": 1.4695620384589554, "SAXENDA": 3.3003074561353016, "SIFROL": 2.793041950447652, "STELARA": 2.27106221744866, "SUSTIVA": 13.683564925922584, "TRULICITY": 1.9330764400129512, "TWINRIX": 1.971510213817771, "VICTOZA": 3.8951975724747423, "XELJANZ": 1.416737888987738, "ZERIT": 22.559685416350383, "ZOSTAVAX": 1.3895604896770346, "ZYPREXA": 9.316903275164472, "null": 1.156255815322196}
\ No newline at end of file
+{"null": 1.9593720167416744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3793.json
index cfeca1e30fb..0d4f33f246b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3793.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3793.json
@@ -1 +1 @@
-{"null": 2.1384350701399795}
\ No newline at end of file
+{"null": 1.4293166421256611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3794.json
index ea8c0cdcbf5..11965949b4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3794.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3794.json
@@ -1 +1 @@
-{"COVID19": 2.0267785406476344, "SOLIRIS": 30.239663279417364, "VAXZEVRIA": 5.532758799183539}
\ No newline at end of file
+{"ABACAVIR": 8.931655246947033, "ABASAGLAR": 2.5685925801274303, "ABATACEPT": 6.3726546320373885, "ABILIFY": 0.71325411041033, "ACETYLSALICYLIC": 12.516584371520928, "ACLIDINIUM": 0.947170604956778, "ACTRAPID": 4.199132643288808, "ADALIMUMAB": 6.774722957229571, "ADCIRCA": 2.5610156637265917, "AERIUS": 0.7388976437832394, "AFINITOR": 0.3130186282971654, "AIMOVIG": 0.7234987273961563, "ALBIGLUTIDE": 13.348327111296932, "ALIMTA": 0.4606681881811391, "ALL": 3.0030386377431832, "AMBRISENTAN": 1.4074420758478998, "AMIKACIN": 1.0625637640986323, "AMINOSALICYLIC": 1.6212969241442745, "ANAKINRA": 11.136177556768857, "ANTIBIOTICS": 1.6210999599791545, "ANTIHYPERTENSIVES": 8.843767800274412, "APIDRA": 1.366401060730272, "APREMILAST": 11.75709119040272, "APREPITANT": 2.810212022339558, "ARANESP": 8.808845220087516, "ARAVA": 6.205711072290763, "ARIPIPRAZOLE": 0.2623027216995294, "ASPARAGINASE": 2.3654487674411824, "ATRIPLA": 0.0345587590991753, "AUBAGIO": 0.4727301916988937, "AVAMYS": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3795.json
index ff519600656..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3795.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3795.json
@@ -1 +1 @@
-{"ACLASTA": 5.182508495608797, "ADALIMUMAB": 2.3652135048073237, "AERIUS": 3.4655079080431586, "ALEMTUZUMAB": 1.2099110576403338, "ALIMTA": 1.8636136328567048, "AMIKACIN": 2.231844898558922, "AMINOSALICYLIC": 3.4421082558839657, "APROVEL": 2.614778871958837, "ARAVA": 1.1626541225866651, "ATEZOLIZUMAB": 6.289550208532255, "AVELUMAB": 5.186145496372268, "AXITINIB": 16.758122107128052, "AZATHIOPRINE": 2.6453429131154853, "BAVENCIO": 4.956567357485743, "BEDAQUILINE": 7.728451731313643, "BETAFERON": 3.45065821253789, "BIKTARVY": 1.166933875001468, "BRAFTOVI": 1.565280143307236, "BRILIQUE": 1.0454473774759296, "CANCIDAS": 2.1209667609712053, "CANNABIDIOL": 2.665927530092933, "CASPOFUNGIN": 1.073616934791368, "CELLCEPT": 1.0742098967652234, "COAPROVEL": 3.0447273944044584, "COMBIVIR": 5.510310798753819, "COTELLIC": 3.553001960603466, "CRIXIVAN": 6.169405596624159, "CUBICIN": 1.8312338464879667, "DABRAFENIB": 2.43402874286642, "DELAMANID": 2.6335387304733926, "DEXAMETHASONE": 1.0558485901420305, "EFAVIRENZ": 1.901974617439265, "EMTRICITABINE": 1.58354225222928, "EPIVIR": 4.135144464804229, "ERLOTINIB": 45.456878755849566, "ESOMEPRAZOLE": 1.6044896825459416, "EUCREAS": 3.5073875534566032, "EXJADE": 1.8878425266330383, "FEBUXOSTAT": 1.7594459584023925, "FULVESTRANT": 1.922764159250576, "GALVUS": 3.419609152059509, "GAZYVARO": 2.020561315200754, "GLIBENCLAMIDE": 2.4547530042717267, "HEPSERA": 3.6994466954406735, "IBUPROFEN": 1.5229815887619038, "IMATINIB": 1.720468971400097, "INFLIXIMAB": 1.322770789475909, "INLYTA": 2.2156750662270026, "INVIRASE": 10.170352798083334, "IPILIMUMAB": 25.422253598697, "IRBESARTAN": 1.0163968090442237, "ISENTRESS": 4.0609684490335285, "KAFTRIO": 1.4750228893643391, "KALETRA": 4.738105560542512, "KEPPRA": 1.7120318783593451, "KEYTRUDA": 6.661492202102698, "KISQALI": 3.111126885078716, "KIVEXA": 4.221094782526648, "LAMIVUDINE": 3.5392965537070853, "LEFLUNOMIDE": 3.167326315168878, "LEVETIRACETAM": 1.0872102233521688, "LEVOFLOXACIN": 1.8574438687133477, "LIBTAYO": 7.803725110597868, "MEKINIST": 2.3985144491506976, "MERCAPTOPURINE": 2.245985655132154, "METHOTREXATE": 2.107396992549177, "MICARDIS": 1.7367917786778029, "MULTAQ": 3.08676594123693, "NEVIRAPINE": 7.86872550732801, "NIVOLUMAB": 8.061960965788677, "NORVIR": 6.5386685202581765, "NOVONORM": 7.685350525024852, "NOXAFIL": 2.826114714885663, "OLANZAPINE": 1.0811566944576592, "OPDIVO": 9.805443579049854, "PACLITAXEL": 1.0706853304423365, "PEMBROLIZUMAB": 7.479720119548079, "REBETOL": 1.60143399696816, "REMICADE": 1.093051083572758, "REYATAZ": 7.748112676319753, "RIBOCICLIB": 2.631150189797532, "ROACTEMRA": 2.1674650179273898, "SOVALDI": 3.55365924842276, "SUSTIVA": 8.30024654642637, "TAMIFLU": 4.316767633661138, "TEMODAL": 1.6981040638802805, "THALIDOMIDE": 1.986591645447708, "TIVICAY": 4.701953903118595, "TOCILIZUMAB": 6.490518867366277, "TRACLEER": 1.6136004071835786, "TRIUMEQ": 3.0237708836892208, "TWINRIX": 2.3696994369557247, "VEKLURY": 2.9559867798437365, "VFEND": 3.4170283704533717, "VICTOZA": 1.4020084387385905, "VILDAGLIPTIN": 7.64271220380885, "VIMPAT": 1.074344358648058, "VIRAMUNE": 28.122670851311444, "VIREAD": 1.422997901311506, "VORICONAZOLE": 2.4983580605679574, "VOTRIENT": 2.16004884432652, "XALKORI": 2.1524371245495257, "YERVOY": 8.581449838269881, "ZYPREXA": 1.2165084279650096, "null": 1.9343045634089235}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3796.json
index e63431f4714..c34b935d8f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3796.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3796.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 9.863488948402903, "HUMALOG": 16.22729603318962, "TAMIFLU": 12.622450927110243, "TWINRIX": 97.06904459895983, "null": 1.1197444610979337}
\ No newline at end of file
+{"ABACAVIR": 1.127799226713028, "ABASAGLAR": 2.3805343244119905, "ABATACEPT": 2.13721053453374, "ABEMACICLIB": 0.6605347462768564, "ABILIFY": 1.7152380058119594, "ABIRATERONE": 0.7869013223770521, "ABRAXANE": 0.4334852367963375, "ACCOFIL": 1.5724593625813557, "ACE": 1.440071307425798, "ACETIC": 23.070269364319884, "ACLASTA": 0.8802842379624518, "ACLIDINIUM": 0.6188204801183719, "ACTOS": 1.0672258272647557, "ACTRAPHANE": 1.3235958047270036, "ACTRAPID": 1.746431513477785, "ADALIMUMAB": 2.3198660401570628, "ADCIRCA": 0.3490413074686738, "ADEFOVIR": 5.305709499484077, "ADEMPAS": 0.1964806654343635, "ADENURIC": 0.1581510962804337, "ADVAGRAF": 0.3342339699844172, "ADVATE": 1.267079807157507, "AERIUS": 1.0473523533364155, "AFATINIB": 1.5136049169791028, "AFINITOR": 0.5915405807002655, "AFLIBERCEPT": 0.4538539844538443, "AGOMELATINE": 3.684019742427876, "AIMOVIG": 2.3145696173374173, "AJOVY": 1.1895458063518964, "ALDARA": 0.38828551182191, "ALECTINIB": 1.3270576685963948, "ALEMTUZUMAB": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3797.json
index 4b984fd5548..4bab281677b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3797.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3797.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 1130.341188694426}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3798.json
index 8505b67a3a9..7626ae922f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3798.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3798.json
@@ -1 +1 @@
-{"TWINRIX": 982.0740076246668}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3799.json
index 58b01dbdf4f..45cc856a7e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3799.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3799.json
@@ -1 +1 @@
-{"BLOOD": 9765.233574728178}
\ No newline at end of file
+{"ABACAVIR": 9.14315800120726, "ABASAGLAR": 0.6036643182733608, "ABATACEPT": 7.467424440104997, "ABILIFY": 0.7309541828769286, "ACE": 5.28008056330669, "ACTRAPID": 0.9169060643061032, "ADALIMUMAB": 10.019030552929555, "ADCIRCA": 1.3134442470364356, "ADEMPAS": 2.084243444715785, "AFINITOR": 1.4460094501052545, "AGOMELATINE": 4.066895885148028, "AIMOVIG": 7.435204947047585, "ALEMTUZUMAB": 0.2132138956706623, "ALIMTA": 0.2244909189725853, "AMBRISENTAN": 1.019602629252802, "AMGEVITA": 10.769092597570276, "AMIKACIN": 3.8688369079297513, "AMINOSALICYLIC": 1.124226666472154, "ANAGRELIDE": 9.591486456677035, "ANAKINRA": 10.474060525146315, "ANORO": 0.240848160399347, "APIDRA": 0.6352411051109088, "APIXABAN": 0.0743473821564161, "APREMILAST": 5.091118304412586, "APREPITANT": 7.682090277745229, "APROVEL": 0.4008912389154485, "ARANESP": 7.089619003007887, "ARAVA": 14.616084028582849, "ARIPIPRAZOLE": 0.7034163400940413, "ATAZANAVIR": 0.4842789441591628, "ATRIPLA": 0.0434245024505142, "AUBAGIO": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/38.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/38.json
index b27276152cf..5e471e95b97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/38.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/38.json
@@ -1 +1 @@
-{"CHAMPIX": 8.849465175938487, "XYREM": 109.88972220291755, "null": 2.236525450824806}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/380.json
index 7d93630b5e6..d22ea2347d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/380.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/380.json
@@ -1 +1 @@
-{"AFINITOR": 1.396771958764619, "AUBAGIO": 4.84851190289544, "BENLYSTA": 1.2239470231947114, "BUPIVACAINE": 8.944729713295086, "CLOPIDOGREL": 1.2835031232998768, "CYTARABINE": 1.0274208660870396, "ENTYVIO": 4.069630284296669, "GARDASIL": 1.185780802637925, "HUMIRA": 3.516115873283779, "INFLIXIMAB": 6.970024780586294, "INSULIN": 1.346864706771549, "JANUVIA": 1.2140541589130125, "KEPPRA": 1.495354057906294, "LYRICA": 1.2529891368997566, "MEMANTINE": 19.12740493642513, "METHOTREXATE": 1.162410385913777, "OCEAN": 143.4849730525466, "OFEV": 2.206531905684396, "OLANZAPINE": 1.726370226063327, "PEGASYS": 1.012075206327277, "PLAVIX": 1.3367404639041875, "SUTENT": 1.0782039985028689, "TOVIAZ": 2.86666338473011, "VFEND": 1.2217016318357967, "XELJANZ": 1.1507003827215343, "XTANDI": 1.7494246013582335, "ZYPREXA": 1.6981942105465797, "null": 2.018061518334978}
\ No newline at end of file
+{"JAKAVI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3800.json
index 748d1251875..d5baa90ddfd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3800.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3800.json
@@ -1 +1 @@
-{"ABACAVIR": 1.6254223329148154, "ALEMTUZUMAB": 14.717400918668078, "BARACLUDE": 68.1807118252519, "BEDAQUILINE": 6.192876186137739, "BIKTARVY": 5.74237078064502, "CELLCEPT": 7.075289590893658, "CICLOSPORIN": 4.459396790664978, "COMBIVIR": 9.94832876686307, "CYTARABINE": 5.271113976880163, "DEXAMETHASONE": 1.830911602063923, "DOXORUBICIN": 29.3846056265272, "EMTRICITABINE": 20.994179313240178, "ENTECAVIR": 113.90205205799128, "EPIVIR": 15.767705158215668, "HEPSERA": 40.75201156813115, "HIZENTRA": 9.958667306868112, "HUMALOG": 1.1619225059476297, "HUMIRA": 2.2108138111033178, "LAMIVUDINE": 23.88655440692921, "MABTHERA": 12.968281761654218, "METHOTREXATE": 1.7107236100639052, "PEGASYS": 1.9648611549794333, "PRIVIGEN": 10.453215321051678, "RINVOQ": 3.8459932689346337, "RITUXIMAB": 16.74158960573574, "SIMPONI": 2.785829428961921, "STELARA": 2.38344385803842, "STRIBILD": 2.094615756278807, "TENOFOVIR": 66.05944286504219, "TREMFYA": 5.033579434180123, "TWINRIX": 13.811064000770486, "VEMLIDY": 66.57821702822208, "VIREAD": 8.142364790830603, "ZYPREXA": 1.9408680603699613}
\ No newline at end of file
+{"null": 1.4683613789688683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3801.json
index eb3d5314830..41e1aa6a9bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3801.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3801.json
@@ -1 +1 @@
-{"HEPSERA": 191.44061970449027, "VEMLIDY": 1966.8875608376236, "VIREAD": 254.68624259722085}
\ No newline at end of file
+{"HUMIRA": 38.96867419144685, "null": 1.0444875074945448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3802.json
index f5fbbee71ff..a5add0d0214 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3802.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3802.json
@@ -1 +1 @@
-{"ADEFOVIR": 541.6693372279842, "BARACLUDE": 1452.9984802120198, "BIKTARVY": 11.023349431784432, "ENTECAVIR": 398.5147792574245, "HEPSERA": 338.42826030452915, "PEGASYS": 3.472633003225663, "TENOFOVIR": 193.33614043315708, "TRUVADA": 2.323754783340984, "VEMLIDY": 801.0197711433434, "VIREAD": 150.2480570451599}
\ No newline at end of file
+{"CICLOSPORIN": 2.1170333890990807, "COAPROVEL": 12.394735019456135, "INFLIXIMAB": 17.692189066382436, "OLANZAPINE": 9.74827803226201, "VFEND": 13.726665512693025, "VORICONAZOLE": 30.833456662155744, "null": 3.953092036140179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3803.json
index b6ab4f54387..7de37e30da9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3803.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3803.json
@@ -1 +1 @@
-{"TWINRIX": 2031.5442067160168}
\ No newline at end of file
+{"ABACAVIR": 2.100719136037982, "ARIPIPRAZOLE": 16.40714526023001, "CICLOSPORIN": 2.762356420483742, "CRESEMBA": 67.31762036114814, "ENTYVIO": 4.902507676548333, "INSULIN": 4.427269224871608, "KEPPRA": 2.6875317895988244, "LEVETIRACETAM": 4.758191441114706, "NOXAFIL": 65.37934506990794, "OLANZAPINE": 1.889106426557957, "POSACONAZOLE": 86.68917342704319, "RAPAMUNE": 15.15228615509752, "SOLIRIS": 3.126765410390254, "STELARA": 16.40137401593207, "TACROLIMUS": 20.324218023469687, "VFEND": 24.51036620670869, "VORICONAZOLE": 104.16445050301728, "null": 1.5139809594709617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3804.json
index 2d7ad40e229..5d3fda3f14f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3804.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3804.json
@@ -1 +1 @@
-{"null": 1.1389022776322184}
\ No newline at end of file
+{"CRIXIVAN": 124.1234648259444, "KALETRA": 22.530334227083223, "null": 1.7141204156671084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3805.json
index 020b05e960f..4043a0b21f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3805.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3805.json
@@ -1 +1 @@
-{"ARAVA": 4.632450185080048, "HIZENTRA": 38.189111717167016, "HUMAN": 43.11138032909053, "KIOVIG": 119.908424629118, "PRIVIGEN": 208.86329001087176, "null": 1.026134922824228}
\ No newline at end of file
+{"ADALIMUMAB": 0.1673190384422149, "AFINITOR": 1.724927124115802, "ATRIPLA": 0.2964859985014849, "CABOTEGRAVIR": 36.35144395263132, "CASPOFUNGIN": 12.284408923300033, "CELLCEPT": 5.628089213127381, "CETRORELIX": 328.1129832369037, "CICLOSPORIN": 6.797564857698681, "DEXAMETHASONE": 1.1255879779610165, "EFAVIRENZ": 4.904298497000596, "ENTYVIO": 17.019534487158037, "FYCOMPA": 11.044919091057174, "HEMLIBRA": 11.93836889004657, "HUMIRA": 9.049814529372387, "INFLIXIMAB": 24.54791871576932, "KALETRA": 2.4322068800578385, "KEPPRA": 4.1597534378370415, "LACOSAMIDE": 8.494667313459026, "LEVETIRACETAM": 7.498197467674996, "LUMACAFTOR": 575.3483451786454, "METHOTREXATE": 0.9296663037879702, "NORVIR": 5.582330660875571, "NOXAFIL": 27.332020931715466, "OLANZAPINE": 1.0956251900616516, "POSACONAZOLE": 18.90997515650169, "RAPAMUNE": 15.09851901212829, "REKAMBYS": 57.38686858310708, "REMICADE": 7.475170415621323, "SIMPONI": 1.0971736527145384, "SOLIRIS": 1.6503952023267154, "STELARA": 9.537489615354945, "TACROLIMUS": 20.65286278363047, "VFEND": 14.051209239510868, "VORICONAZOLE": 26.564999521990018, "XENICAL": 155.18513374722136, "ZYPADHERA": 4.112976623075581, "null": 2.1368269159039857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3806.json
index 8bdcd969014..c3dea8b9d29 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3806.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3806.json
@@ -1 +1 @@
-{"AFINITOR": 1.6154080711740348, "BARACLUDE": 56.961362588635126, "BEVACIZUMAB": 12.350542085568891, "BIKTARVY": 3.928729798195381, "BORTEZOMIB": 29.34498032691541, "BUSULFAN": 5.724345535841566, "CARMUSTINE": 15.516634258955971, "CELSENTRI": 37.90994644162344, "CICLOSPORIN": 7.733244841865264, "COSENTYX": 1.122661540909513, "CYTARABINE": 6.873191511730263, "DARZALEX": 4.779851875646584, "DEXAMETHASONE": 11.16293026474227, "DOXORUBICIN": 44.05824269346044, "ENTECAVIR": 137.78668538384193, "EPCLUSA": 9.815736919356604, "HARVONI": 30.71656075311177, "HEPSERA": 44.65817401307872, "JAKAVI": 9.476876568668152, "LAMIVUDINE": 30.03203632840066, "MABTHERA": 60.83092471733034, "MELPHALAN": 17.29619037851157, "METHOTREXATE": 7.572580587747764, "NEXAVAR": 2.228811547482642, "RIBAVIRIN": 14.056526656310446, "RITUXIMAB": 83.26249184874018, "SIMEPREVIR": 51.36221335161509, "SIMPONI": 1.871700778868706, "SOVALDI": 24.750836315201404, "TENOFOVIR": 90.9693594286036, "VIREAD": 14.49678923427908}
\ No newline at end of file
+{"CELLCEPT": 12.574512552425237, "CICLOSPORIN": 5.692230337928092, "SUBOXONE": 12.9093054610857, "null": 3.249768240018508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3807.json
index 7c9c438f454..1b822b9079f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3807.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3807.json
@@ -1 +1 @@
-{"TWINRIX": 2788.5962976576443}
\ No newline at end of file
+{"ABACAVIR": 0.2487707815959202, "ABILIFY": 0.5478701333604004, "ARIPIPRAZOLE": 18.92317647397986, "ATAZANAVIR": 6.195155478144248, "ATRIPLA": 0.0695315872941913, "BRILIQUE": 0.9442639586351984, "BRIVIACT": 5.952001614153716, "BUDESONIDE": 0.4099805252779046, "BUPRENORPHINE": 1.4935408795263052, "BUSULFAN": 0.8866801757074532, "CANCIDAS": 4.169222468464975, "CANNABIDIOL": 22.37793394794624, "CARBIDOPA": 4.10690981762254, "CELECOXIB": 2.765427457674132, "CELLCEPT": 3.3885436474820745, "CICLOSPORIN": 7.442171122108588, "CLOPIDOGREL": 0.6565840083287718, "CRESEMBA": 7.179809644930304, "CYMBALTA": 0.4615957772910488, "DEXAMETHASONE": 0.9646603946730128, "DULOXETINE": 2.9435675176806075, "ELIQUIS": 0.5377613345152049, "ENVARSUS": 98.44054676239128, "ESOMEPRAZOLE": 3.482212468310215, "EVEROLIMUS": 2.9005944344684376, "FENTANYL": 2.7285927356506594, "GLIVEC": 2.895876863807616, "HEMLIBRA": 4.259139563805238, "HYDROCORTISONE": 1.5047441814154656, "IBUPROFEN": 1.5988250383968166, "INTELENCE": 6.767579741795777, "KAFTRIO": 1.2740286511605523, "KALETRA": 7.889974125175983, "KEPPRA": 2.210521945618221, "LEVETIRACETAM": 2.8144704735512738, "LEVOFLOXACIN": 0.3314001855360297, "LOPINAVIR": 24.87956277607421, "LYRICA": 1.740548548111448, "METHOTREXATE": 1.2348168218794957, "MICARDIS": 1.4314120307644125, "MIDAZOLAM": 2.1803285043453045, "MYCOPHENOLATE": 3.01768961820426, "NORVIR": 2.8310270506297863, "NOT": 1.439707932888982, "NOXAFIL": 10.15602281033183, "OLANZAPINE": 4.029688181490151, "OXYBUTYNIN": 3.111590089963627, "POSACONAZOLE": 10.8114680578307, "PREGABALIN": 4.920057784010582, "RAPAMUNE": 13.010780518325117, "RISPERIDONE": 2.6775494459026072, "RITONAVIR": 12.3942102715817, "SILDENAFIL": 1.5803060172922527, "SODIUM": 21.253946300848245, "STELARA": 0.225920312201048, "TACROLIMUS": 28.988626951777054, "TAMIFLU": 0.7515803405416709, "TASIGNA": 0.4720599736873043, "TELMISARTAN": 2.8350645496234783, "TOBRAMYCIN": 19.419871543939724, "VFEND": 21.36679761681834, "VIMPAT": 1.5686214670222132, "VORICONAZOLE": 19.49937869865424, "VORTIOXETINE": 12.777375292865074, "ZYPADHERA": 4.2712946673072505, "ZYPREXA": 2.7521604163721265, "null": 3.5248882783114976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3808.json
index 63c16216958..fa2e176ed84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3808.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3808.json
@@ -1 +1 @@
-{"HIZENTRA": 51.77164990739778, "HUMAN": 55.46440502694127, "PRIVIGEN": 195.02144887657207, "null": 1.2558740368532824}
\ No newline at end of file
+{"FULVESTRANT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3809.json
index 8b0985437d8..3d10e40cbce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3809.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3809.json
@@ -1 +1 @@
-{"BEDAQUILINE": 93.71277875548957, "CICLOSPORIN": 9.287395609739743, "PEGASYS": 13.26700719516867}
\ No newline at end of file
+{"null": 1.006633644640497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/381.json
index e07713cda33..3c40a301c5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/381.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/381.json
@@ -1 +1 @@
-{"ENTYVIO": 22.93618007380296, "PEGASYS": 4.660851110761988, "SUTENT": 10.1634339600209}
\ No newline at end of file
+{"FENTANYL": 25.081074095529964, "null": 3.1737202397266704}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3810.json
index 82be7e00e1d..b94d8606e04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3810.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3810.json
@@ -1 +1 @@
-{"HIZENTRA": 50.52758032331322}
\ No newline at end of file
+{"null": 3.6857187783012617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3811.json
index 9b3deada88a..4fccdde9d49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3811.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3811.json
@@ -1 +1 @@
-{"ABACAVIR": 1.192182293013802, "BEDAQUILINE": 2.311880269565149, "BIKTARVY": 1.3013981337423834, "BLOOD": 86.9189159251557, "BOCEPREVIR": 9.49460475171496, "BUPRENORPHINE": 2.616354011731244, "CELLCEPT": 2.780995653242304, "CICLOSPORIN": 1.652985181558995, "DACLATASVIR": 192.08409143741375, "DAKLINZA": 154.85679920233505, "DASABUVIR": 40.50535812993751, "DESCOVY": 3.2448239462563198, "DOLUTEGRAVIR": 4.765148696447183, "EPCLUSA": 135.3773960995886, "EPIVIR": 2.395455472995975, "EXVIERA": 8.994358041029216, "HARVONI": 209.96740766911051, "HUMAN": 5.800916360538624, "INCIVO": 2.138588627408528, "INTRONA": 1.6813160279730306, "LEDIPASVIR": 39.02832528485297, "MABTHERA": 1.1863603941504808, "MYCOPHENOLATE": 4.713906280729081, "NORVIR": 2.3846614160916837, "NOVOSEVEN": 2.0385591352302272, "NPLATE": 1.058466283832175, "OLYSIO": 119.83930948018384, "PEGASYS": 10.999716272042145, "PEGINTERFERON": 31.911282572903563, "PEGINTRON": 5.7032020278508, "REBETOL": 65.45724903225579, "REYATAZ": 3.097400349434636, "RIBAVIRIN": 298.6586198673844, "SIMEPREVIR": 234.90436308015376, "SOFOSBUVIR": 72.37544742557667, "SOVALDI": 140.67988130454347, "STELARA": 1.5399496295642914, "SUBOXONE": 6.472613655317582, "ZEPATIER": 53.639794945656256, "ZYPREXA": 1.1862827790225137}
\ No newline at end of file
+{"LEMTRADA": 46.9529179390628, "null": 2.497500082994929}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3812.json
index da57299f04d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3812.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3812.json
@@ -1 +1 @@
-{"OLYSIO": 530.1486413459464}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3813.json
index c81e0cb1d7b..805ac231e7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3813.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3813.json
@@ -1 +1 @@
-{"OLYSIO": 68.92528886197735, "PEGASYS": 29.76771912571276, "PEGINTRON": 18.03834365547028, "RIBAVIRIN": 90.82319023474894, "SOVALDI": 76.9606002229754}
\ No newline at end of file
+{"ABACAVIR": 0.5726154415351102, "AERIUS": 3.526958171317896, "ALIMTA": 0.454574545821142, "AMIKACIN": 19.398358083179648, "ANAKINRA": 1.164304637419682, "APIXABAN": 0.2769934324786735, "APROVEL": 1.205173129649002, "ARANESP": 0.4399499550503375, "ARAVA": 0.0492288147983298, "ARIPIPRAZOLE": 0.6594104222916589, "ARIXTRA": 3.772564307265488, "ATAZANAVIR": 0.7818508687739147, "ATRIPLA": 0.0366016232831218, "AZTREONAM": 8.918864062711494, "BEDAQUILINE": 1.040246998523757, "BORTEZOMIB": 2.7223125418741123, "BRAFTOVI": 0.6692464580245951, "BRIDION": 2.77366468988606, "BRILIQUE": 1.3369061589467437, "CANCIDAS": 14.975652601815009, "CASPOFUNGIN": 3.90640402459066, "CELECOXIB": 4.8625093916242506, "CICLOSPORIN": 0.3985631138776948, "CLOPIDOGREL": 0.9031522003364708, "COBIMETINIB": 45.40339313184336, "COMIRNATY": 0.015484436521899, "COTELLIC": 34.59723030316257, "CUBICIN": 10.729340102504926, "CYMBALTA": 0.276782021685296, "DABRAFENIB": 3.60401680676962, "DAPTOMYCIN": 23.596180667483697, "DARZALEX": 0.9460619751765336, "DELAMANID": 6.907415060223075, "DESLORATADINE": 2.3656906914215536, "DEXAMETHASONE": 0.9761635696306936, "ELIQUIS": 0.0936669525610704, "EMTRICITABINE": 4.322025762055895, "ENOXAPARIN": 0.9248571615080567, "ERLEADA": 9.465050809935, "ERTAPENEM": 17.239199096755485, "ESOMEPRAZOLE": 5.356461103240522, "EXFORGE": 0.6721882556922626, "FEBUXOSTAT": 5.734654195525256, "FENTANYL": 0.6316011672523097, "GANCICLOVIR": 4.233071746565882, "HUMAN": 1.029314389671657, "IBUPROFEN": 1.810681986892622, "INCIVO": 13.481308793054993, "INTELENCE": 7.953018479796488, "INVANZ": 13.513559208705493, "IPILIMUMAB": 1.899234004544844, "IRBESARTAN": 2.2735509593897856, "ISENTRESS": 17.60677404815595, "JANUVIA": 0.5639580282312859, "JARDIANCE": 0.1511307927623471, "KEPPRA": 5.79703559091276, "KEYTRUDA": 0.1300186009519799, "KIVEXA": 4.262973902770463, "LACOSAMIDE": 2.9152413046465577, "LANTUS": 0.2619630867151697, "LEVETIRACETAM": 13.916084274903094, "LEVOFLOXACIN": 4.454503983966503, "LYRICA": 1.5964419177048987, "MEKINIST": 0.969974561850654, "MICARDIS": 1.446919393668788, "MIDAZOLAM": 1.5230131469102235, "NEVIRAPINE": 9.588319070863143, "NEXAVAR": 0.270726193512354, "NORVIR": 5.0787652794900575, "NOT": 1.246752143725886, "OCTREOTIDE": 7.934345023941725, "OLANZAPINE": 1.7985684335921648, "OPDIVO": 1.036302531957994, "OSSEOR": 36.9002321363029, "PANTOPRAZOLE": 6.754905178149402, "PEGASYS": 1.2675393239890993, "PEGINTERFERON": 11.3910755217354, "PEGINTRON": 0.1561177826545405, "PLAVIX": 0.5663401128477205, "PRADAXA": 1.909081623504359, "PREGABALIN": 0.7114542120448207, "PROTELOS": 27.71664721093901, "REVLIMID": 4.84042603803958, "RIBAVIRIN": 2.9904915604709, "RITUXIMAB": 0.3898223716349205, "ROACTEMRA": 0.568827179008532, "SPIKEVAX": 0.0234281057079622, "SPIRONOLACTONE": 6.398986065335149, "SUFENTANIL": 1.5123817873169152, "TAMIFLU": 1.2777762425760868, "TELMISARTAN": 2.4105719907855825, "TEMODAL": 1.9771320186582355, "TEMOZOLOMIDE": 4.737676161759718, "THALIDOMIDE": 5.232076000148883, "TOZINAMERAN": 0.0286667964083628, "TRUVADA": 0.0690629961810368, "VAXZEVRIA": 0.0185363995581986, "VFEND": 1.6056062864960712, "VIMPAT": 3.8735614484050793, "VIRAMUNE": 4.317324225377931, "VORICONAZOLE": 1.6093067174224542, "XARELTO": 0.6894083403589464, "ZELBORAF": 6.589780037536045, "ZONISAMIDE": 7.465738990781831, "ZYPREXA": 0.8785984728311136, "null": 3.8901432186537663}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3814.json
index 226e71ee95e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3814.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3814.json
@@ -1 +1 @@
-{"DAKLINZA": 151.8364867932985, "EPCLUSA": 115.41334055001042, "HARVONI": 49.2195562710512, "PEGASYS": 17.49627553969152, "RIBAVIRIN": 204.29920361086772, "SOVALDI": 259.072465501785}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3815.json
index 8e450f3422e..559e63b98c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3815.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3815.json
@@ -1 +1 @@
-{"null": 1.3226815133593934}
\ No newline at end of file
+{"null": 2.324060307247745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3816.json
index 99cb82d985a..f87947095a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3816.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3816.json
@@ -1 +1 @@
-{"PEGASYS": 40.57473560326963}
\ No newline at end of file
+{"ABACAVIR": 8.986599769085734, "ABILIFY": 0.2670400765534882, "ADALIMUMAB": 0.381985723065564, "ADEFOVIR": 162.91823534825764, "AFATINIB": 46.1857950846204, "AFINITOR": 0.2358150234959878, "ALECTINIB": 24.23544654161696, "ALEMTUZUMAB": 4.333670594674488, "AMIKACIN": 31.621807338038334, "AMINOSALICYLIC": 6.877050539761385, "AMPRENAVIR": 27.7725328581426, "ANIDULAFUNGIN": 32.48423929122619, "ARANESP": 0.563633101633766, "ARAVA": 0.3033177617120635, "ARIPIPRAZOLE": 3.705517975904417, "ASPARAGINASE": 0.8082219734907073, "ATAZANAVIR": 14.081894325936908, "ATRIPLA": 0.7191363482871251, "AVAPRITINIB": 85.13210303001547, "AZACITIDINE": 2.460042616203085, "AZATHIOPRINE": 1.2519987223481064, "AZTREONAM": 14.390025647687796, "BARACLUDE": 56.71241890902205, "BASILIXIMAB": 14.521440558411316, "BEDAQUILINE": 4.198202117026216, "BEVACIZUMAB": 4.202504207876552, "BIKTARVY": 13.496253773232944, "BORTEZOMIB": 4.24769533979567, "BOSULIF": 2.127813673801134, "BOSUTINIB": 54.21982733756069, "BOTULINUM": 2.5908981937930244, "BRIVARACETAM": 9.846605225472588, "BUDESONIDE": 0.4745759585075321, "BUSULFAN": 2.14038094830292, "CANCIDAS": 12.67587317565221, "CANNABIDIOL": 2.517949753545401, "CAPECITABINE": 1.7590002343035318, "CARIPRAZINE": 20.66326783732023, "CASPOFUNGIN": 29.75388852693252, "CEFEPIME": 42.43951397031212, "CEFTAZIDIME": 49.459272413470735, "CELSENTRI": 10.89045383743329, "CICLOSPORIN": 4.195714891926675, "CIDOFOVIR": 66.19412812334754, "CIMZIA": 0.4466236765809224, "CLOFARABINE": 5.220164781447125, "CLOPIDOGREL": 3.824268207242101, "COMBIVIR": 1.2133949234344168, "CORTICOSTEROID": 18.7736168755498, "COSENTYX": 0.2031371426557958, "CRIXIVAN": 10.394303020324488, "CRIZOTINIB": 25.86674604070391, "CUBICIN": 11.405141995636962, "CYTARABINE": 3.6682188262294138, "DABRAFENIB": 8.563251101083688, "DACLATASVIR": 3.4354189144129426, "DAKLINZA": 3.862540736610312, "DAPTOMYCIN": 16.96060549943664, "DARUNAVIR": 18.21245276451576, "DARZALEX": 1.0766153467076849, "DASATINIB": 55.84951292110906, "DELAMANID": 3.2004237402802573, "DESCOVY": 9.390049238320705, "DEXAMETHASONE": 2.8762231290013283, "DOCETAXEL": 2.057054354931867, "DOLUTEGRAVIR": 16.338730060176587, "DOXORUBICIN": 2.046394853986681, "DULOXETINE": 1.7966544184212032, "EDURANT": 8.947842229864875, "EFAVIRENZ": 18.75058872077989, "EMTRICITABINE": 28.68399807816939, "EMTRIVA": 19.236133938849942, "ENBREL": 1.0915298661027302, "ENTECAVIR": 109.3203281592032, "EPIVIR": 3.809719538367165, "ERLOTINIB": 127.23124849934706, "ERTAPENEM": 14.90162324672444, "ESKETAMINE": 236.10679660195305, "EVEROLIMUS": 5.273792086447853, "FASLODEX": 0.3159417600721923, "FENTANYL": 0.5716017015058621, "FIDAXOMICIN": 16.348234021143536, "FULVESTRANT": 1.2435282090855688, "GANCICLOVIR": 64.03121628065877, "GEFITINIB": 149.64231670061238, "GENVOYA": 19.78828288861536, "GLIVEC": 11.69634249410196, "HARVONI": 4.306003531993655, "HEPSERA": 48.16925443337597, "HUMALOG": 0.2076993584129482, "HUMAN": 5.124773869719335, "IBRUTINIB": 8.485543119963147, "IBUPROFEN": 0.4393023304984174, "ICLUSIG": 2.6884976361881665, "IMATINIB": 45.847391323599005, "INFLIXIMAB": 1.7532363172544343, "INTELENCE": 5.547178033788962, "IRESSA": 70.67642715786374, "IRINOTECAN": 1.2062123101485085, "ISENTRESS": 5.380172491526457, "JAKAVI": 0.5416988260948953, "KALETRA": 0.9230683030793736, "KEPPRA": 0.711354786157427, "KEYTRUDA": 0.3161915438137074, "LACOSAMIDE": 23.80958056751449, "LAMIVUDINE": 10.233656324555149, "LEVETIRACETAM": 15.653016394293587, "LEVOFLOXACIN": 5.01549074644675, "LOPINAVIR": 4.377913627622504, "LOXAPINE": 16.684796681170937, "LYNPARZA": 1.0565185277415443, "MEKINIST": 2.038281106331965, "METHOTREXATE": 2.298533721246092, "MICAFUNGIN": 9.014122277824814, "MIDAZOLAM": 1.85413572346472, "MYCOPHENOLATE": 3.0396911705658147, "NEVIRAPINE": 6.520830090898225, "NEXAVAR": 0.1538774823864271, "NILOTINIB": 23.846169402817285, "NORVIR": 1.5774648646492848, "NOT": 1.6775706641906132, "OLANZAPINE": 1.381163965886816, "OLAPARIB": 8.3094419787056, "OLYSIO": 1.1915085164751782, "OSELTAMIVIR": 10.3997089083515, "OSIMERTINIB": 104.07428461205674, "PACLITAXEL": 1.4191154192941278, "PANITUMUMAB": 5.462208552802176, "PEGINTERFERON": 0.4672314621270302, "PEMBROLIZUMAB": 1.4740420479630636, "PLAVIX": 1.547800201331701, "POSACONAZOLE": 9.194598382781573, "REYATAZ": 10.274192212131634, "RIBAVIRIN": 1.9556069135469152, "RITUXIMAB": 1.591731742184786, "SOVALDI": 1.3193407632459289, "SPRYCEL": 2.3760629427418105, "STRIBILD": 2.2244384333546305, "TACROLIMUS": 1.7422318623715174, "TAGRISSO": 4.47367629226466, "TAMIFLU": 1.4868081561797075, "TASIGNA": 2.747156827283987, "TECOVIRIMAT": 254.29199408251824, "TELITHROMYCIN": 148.29231174476035, "TEMOZOLOMIDE": 6.000159797207004, "TENOFOVIR": 12.66793728472928, "TIGECYCLINE": 27.68949377920479, "TIVICAY": 3.075588478323166, "TOBRAMYCIN": 9.636538525884005, "TRUVADA": 0.8019438487398858, "VEMLIDY": 6.855741903061904, "VFEND": 0.5301903950004406, "VIRAMUNE": 6.119840934414189, "VIREAD": 4.757009853657179, "VORICONAZOLE": 16.994754019021116, "XTANDI": 0.2184957259395888, "null": 0.5150914826994749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3817.json
index 792a5869073..98660d630c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3817.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3817.json
@@ -1 +1 @@
-{"DAKLINZA": 65.79974705440259, "EPCLUSA": 198.68358075290303, "HARVONI": 145.48517654250932, "OLYSIO": 43.4134411319507, "PEGASYS": 11.618981624459783, "RIBAVIRIN": 208.4716387124404, "SOVALDI": 55.05430937726681}
\ No newline at end of file
+{"BIKTARVY": 183.54765795258527}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3818.json
index c3d50fca4e3..82c80ee066f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3818.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3818.json
@@ -1 +1 @@
-{"CICLOSPORIN": 16.649135311217098, "MYCOPHENOLATE": 46.77960080420841, "RIBAVIRIN": 23.013618978041563, "RINVOQ": 20.70950238902325, "ROACTEMRA": 10.954148654951895}
\ No newline at end of file
+{"null": 3.201168827527945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3819.json
index dd70c219b17..71bea77a4dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3819.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3819.json
@@ -1 +1 @@
-{"AVANDIA": 1.303100338433027, "BRILIQUE": 1.5369577490274335, "BUSILVEX": 14.783695190770024, "CARMUSTINE": 6.311460372249967, "CLOPIDOGREL": 1.3819550122380675, "COAPROVEL": 2.6679218721102904, "COMBIVIR": 2.4135491630461425, "DEXAMETHASONE": 1.1110590635112088, "FEBUXOSTAT": 11.846524798139164, "IBUPROFEN": 1.3394408278983765, "IPILIMUMAB": 2.208515980355958, "ISENTRESS": 3.0026870387222675, "JANUMET": 4.259912244242738, "KALETRA": 2.9289878970262007, "KEPPRA": 2.148045112461197, "KEYTRUDA": 1.4670263837741175, "KISQALI": 3.785607562912243, "LEVETIRACETAM": 1.9825155817597044, "LEVOFLOXACIN": 4.616759946338017, "METHOTREXATE": 1.2471686319714217, "MICARDIS": 2.887657515316995, "MULTAQ": 3.964794264298266, "NEXAVAR": 2.626900605097561, "OLYSIO": 4.657834937980569, "OPDIVO": 2.721252679289698, "PLAVIX": 1.9723934429728065, "REYATAZ": 7.743430362215176, "SAXENDA": 1.581157536436154, "STIVARGA": 1.1306663799978565, "SUBOXONE": 1.5133928948990594, "TAMIFLU": 5.5508965781441, "VFEND": 1.344501198868599, "VIRAMUNE": 9.148280883816811, "VOTRIENT": 1.899754792177533, "ZYPREXA": 1.154711016022527, "null": 2.8892017832673718}
\ No newline at end of file
+{"SUBOXONE": 237.63185643055596, "null": 0.5143141970941679}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/382.json
index ff2eabc4abc..b49973be1eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/382.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/382.json
@@ -1 +1 @@
-{"SUTENT": 36.23832607887527}
\ No newline at end of file
+{"null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3820.json
index 6fe7ac3d83e..2dc0c82277e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3820.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3820.json
@@ -1 +1 @@
-{"null": 1.3598186225810662}
\ No newline at end of file
+{"ATRIPLA": 0.3998494376976175, "BENZODIAZEPINE": 135.42320396809225, "BENZODIAZEPINES": 462.15194297836354, "BUPRENORPHINE": 67.39039117982836, "CYMBALTA": 2.3209729195780286, "FENTANYL": 3.082917995721994, "GLUCAGON": 55.20627207166592, "IBUPROFEN": 4.314457297995316, "KEPPRA": 4.243929569801572, "OLANZAPINE": 3.653794972545934, "OPIOIDS": 169.0674731848615, "SUBOXONE": 31.26446222108259, "XYREM": 26.8361402461562, "null": 1.98605000512178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3821.json
index 2ddec07ae34..038fb570a9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3821.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3821.json
@@ -1 +1 @@
-{"AERIUS": 3.1688140637342554, "ALIMTA": 1.218563718217731, "APROVEL": 3.61523711838298, "ASPARAGINASE": 1.536205815777481, "AZATHIOPRINE": 2.3646911202377066, "BRILIQUE": 2.300149278070388, "CAELYX": 2.79778209103456, "CANCIDAS": 5.708432239383474, "CELLCEPT": 2.1783549978793344, "CLOPIDOGREL": 1.08251342057552, "COAPROVEL": 6.322536131043499, "CRIXIVAN": 5.051583375314272, "CYTARABINE": 1.6886858962639266, "DARUNAVIR": 11.794282110757702, "EFAVIRENZ": 8.67736550825753, "ENOXAPARIN": 2.7480687808331363, "EPIVIR": 6.619742538631544, "ESOMEPRAZOLE": 5.1740598082943725, "GANCICLOVIR": 3.1528992255001183, "GLIBENCLAMIDE": 5.460949687430225, "IBUPROFEN": 2.3294116004471594, "KALETRA": 1.434905865964382, "KEPPRA": 1.8971374653596265, "LEVOFLOXACIN": 1.767047153580578, "NOVONORM": 7.083807913223398, "NOXAFIL": 4.309402186794785, "PANTOPRAZOLE": 8.286009017230423, "PEGINTERFERON": 1.067680044558734, "PEMBROLIZUMAB": 1.6995939693268818, "PLAVIX": 1.5229614302828225, "PRADAXA": 5.7946689001960126, "TAMIFLU": 2.060264767255891, "TRACLEER": 1.6545390155045072, "VFEND": 4.177332069915817, "VIRAMUNE": 21.38444524199395, "VORICONAZOLE": 4.952749714864956, "XARELTO": 2.341395234823331, "null": 4.64496202752805}
\ No newline at end of file
+{"ABATACEPT": 3.0535344804056086, "ADALIMUMAB": 8.838268975352372, "ANAKINRA": 41.446128233003, "ARANESP": 9.05850300677316, "ETANERCEPT": 117.40307272805944, "HUMIRA": 9.789050725069863, "KOGENATE": 316.4478466455078, "NEORECORMON": 367.845356566029, "STELARA": 3.232017229133336, "null": 1.6900985481513209}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3822.json
index 956b7dea19e..79dd67333a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3822.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3822.json
@@ -1 +1 @@
-{"PEGINTERFERON": 51.8312100964621}
\ No newline at end of file
+{"ARANESP": 136.53636450501443, "CELLCEPT": 15.06923659438446, "EPOETIN": 143.78375634679756, "PEGASYS": 2.7744894909161397, "null": 2.5365298012308486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3823.json
index cb7622afe5f..6330757efd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3823.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3823.json
@@ -1 +1 @@
-{"CANCIDAS": 21.26528082258209, "CELLCEPT": 1.5372090261439089, "DOXORUBICIN": 3.974093012982332, "EPIVIR": 10.874454746272315, "FENTANYL": 1.4854973575885584, "FUZEON": 196.6941678065769, "KEYTRUDA": 2.54644489409303, "LEVOFLOXACIN": 1.5464858134322792, "MICARDIS": 4.730475042130308, "NEXAVAR": 2.154395045709915, "OPDIVO": 4.283665611637545, "PEGINTRON": 1.2816529202405416, "PLAVIX": 2.5274009662209256, "STIVARGA": 7.0359841607686455, "TAMIFLU": 18.87629302680123, "VFEND": 5.112324998761247, "VIRAMUNE": 33.2294897419774, "null": 2.746647205373114}
\ No newline at end of file
+{"ADALIMUMAB": 11.131916247995571, "AMINOSALICYLIC": 10.871088511389091, "ANAKINRA": 33.1910186422276, "ARANESP": 10.77953892471145, "AZATHIOPRINE": 15.006967535127435, "CIMZIA": 5.189775273766961, "EMICIZUMAB": 540.4426166802308, "ENTYVIO": 47.250327320296016, "HEMLIBRA": 158.56430117260803, "HUMIRA": 18.91864718758512, "INFLIXIMAB": 50.01696414162971, "NEULASTA": 18.032124041146933, "null": 0.2091424066398265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3824.json
index 2d66adec518..8360ee590d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3824.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3824.json
@@ -1 +1 @@
-{"null": 2.2450342229325893}
\ No newline at end of file
+{"null": 9.918400172113037}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3825.json
index 2efb3a6862c..40e22628d23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3825.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3825.json
@@ -1 +1 @@
-{"ABACAVIR": 1.3065138882831682, "BEDAQUILINE": 24.049799982381305, "BRILIQUE": 4.820094858388861, "DELAMANID": 24.296871103636636, "ERLOTINIB": 101.07373888247392, "IBUPROFEN": 2.321636507960174, "ISENTRESS": 6.906792872458438, "LEVOFLOXACIN": 2.9231998092304585, "MULTAQ": 6.139875882219048, "PEMBROLIZUMAB": 3.7612757727925183, "VIRAMUNE": 18.58154531849236, "VOTRIENT": 2.0525038160155784, "ZYPREXA": 1.3675739952248984, "null": 2.9248328510803927}
\ No newline at end of file
+{"ARANESP": 712.9213778540573, "DARBEPOETIN": 1909.175898647532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3826.json
index da3406cd359..48b5627cf97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3826.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3826.json
@@ -1 +1 @@
-{"CICLOSPORIN": 8.729161066821439}
\ No newline at end of file
+{"BUVIDAL": 1356.4727640371566, "HEMANGIOL": 2301.0846467385527, "SAXENDA": 38.86317134855557, "VAXZEVRIA": 0.3033873027447951, "VICTOZA": 50.32093933856398, "null": 0.9535726062393476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3827.json
index ee200c5e855..08074da22d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3827.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3827.json
@@ -1 +1 @@
-{"null": 2.936222849208289}
\ No newline at end of file
+{"ABATACEPT": 5.7123329959021385, "ADALIMUMAB": 24.90428416953105, "ARAVA": 2.116436129477965, "AZATHIOPRINE": 5.220542878375118, "BARACLUDE": 54.379619228667366, "BUPRENORPHINE": 13.554122218892276, "CLOPIDOGREL": 1.1470455557680834, "DULOXETINE": 5.529379048135286, "ENBREL": 3.5955307219698853, "FENTANYL": 34.38290815255834, "HEPSERA": 15.61960145484399, "IRESSA": 16.780137723758106, "LYRICA": 2.2252912498015185, "null": 1.054363514457194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3828.json
index 5d079acdbec..17c56dbc394 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3828.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3828.json
@@ -1 +1 @@
-{"null": 1.5870959564812956}
\ No newline at end of file
+{"ABATACEPT": 10.424361328446915, "ABILIFY": 1.9445578273298785, "ADALIMUMAB": 25.176768577985555, "AMINOSALICYLIC": 8.440006691825143, "APREMILAST": 27.00138262471977, "ARAVA": 22.939236379392327, "CIMZIA": 1.0728159605327456, "COSENTYX": 1.4805905870342102, "DEXAMETHASONE": 1.670011753876338, "ENBREL": 16.551201998619682, "null": 0.2198782867618026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3829.json
index c67fbe4f2ab..6dbef35030c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3829.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3829.json
@@ -1 +1 @@
-{"BARACLUDE": 27.412576373237403, "CABOMETYX": 23.984397296438274, "CABOZANTINIB": 29.996389152386485, "CICLOSPORIN": 1.2698256082258128, "DACLATASVIR": 58.54203475195683, "DAKLINZA": 55.46603061317785, "ENTECAVIR": 9.974535134057517, "EPCLUSA": 28.278685580557507, "EXVIERA": 23.950892692541142, "GLECAPREVIR": 577.3223763570121, "HARVONI": 58.42611373237201, "HEPSERA": 12.485046651037486, "INCIVO": 2.581830366445286, "NEXAVAR": 523.0707210796588, "OCALIVA": 2.697551802508707, "OLYSIO": 20.56345777099131, "PEGASYS": 2.308174788477719, "PEGINTERFERON": 6.808505291656262, "PEGINTRON": 2.463860480363384, "REBETOL": 13.099374481068653, "REGORAFENIB": 24.1944534690259, "RIBAVIRIN": 21.61363963307781, "SOFOSBUVIR": 23.772727215694548, "SORAFENIB": 45.14421136202953, "SOVALDI": 48.2368636220552, "STIVARGA": 17.792609847090493, "VEMLIDY": 23.079483594531577, "VIREAD": 2.336098690931376}
\ No newline at end of file
+{"FENTANYL": 23.7009207084096, "null": 3.0760004219642987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/383.json
index f1be04a3d3a..c4aafa35e6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/383.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/383.json
@@ -1 +1 @@
-{"null": 1.3089659008738577}
\ No newline at end of file
+{"BRIDION": 177.18371626482366, "FENTANYL": 43.74026045613645, "MIDAZOLAM": 85.73327635780471, "null": 2.958274790227484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3830.json
index 55a7b69cc0a..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3830.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3830.json
@@ -1 +1 @@
-{"ALIMTA": 4.680294300918038, "AUBAGIO": 1.868851787892442, "AVANDIA": 1.2472554265355498, "BUSULFAN": 1.5590182464577804, "CANCIDAS": 8.8907234308636, "CLOPIDOGREL": 1.426461307301497, "CYMBALTA": 1.101454008769948, "CYTARABINE": 1.1157274977721665, "DEXAMETHASONE": 1.1626671344754165, "EFAVIRENZ": 9.160556287000247, "ENOXAPARIN": 4.3368954949522, "ESOMEPRAZOLE": 4.238009404699844, "EXJADE": 1.3146919211318653, "GILENYA": 17.187168117464328, "IBUPROFEN": 1.3672351574767976, "ISENTRESS": 4.159450809627482, "JANUVIA": 1.1641401484607203, "KAFTRIO": 5.460397552586802, "KALETRA": 7.009012108048632, "KEPPRA": 1.251686486180095, "KISQALI": 3.399987723554554, "LEVETIRACETAM": 1.1385150811812332, "LEVOFLOXACIN": 2.52802188802698, "METHOTREXATE": 2.2773875282915883, "MICARDIS": 3.5332855053765573, "MULTAQ": 59.08653909835128, "OLANZAPINE": 1.9067064014994557, "OPDIVO": 1.2570708495217755, "PLAVIX": 2.4162069549370897, "ROACTEMRA": 3.94479832497383, "TAMIFLU": 1.687594676109764, "TEMODAL": 6.302324232807426, "VEKLURY": 13.352466463644827, "VFEND": 7.0048517636798895, "VORICONAZOLE": 3.2721592095315155, "VOTRIENT": 1.818334580426421, "ZYPREXA": 1.9190344558904249, "null": 2.9007881682328405}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3831.json
index ba54d8c2506..8f05b3ec8d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3831.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3831.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 32.14990981262236}
\ No newline at end of file
+{"ADALIMUMAB": 0.9757473192213548, "ANAKINRA": 4.411145635859244, "ARAVA": 0.4996458860527022, "BUPRENORPHINE": 37.22909463069427, "ENBREL": 28.33158551255392, "FENTANYL": 12.247855887259036, "LYRICA": 4.708137716483887, "OLANZAPINE": 1.01174119298759, "PREGABALIN": 22.504109193283664, "SUBOXONE": 1.5078162720745532, "ZYPREXA": 2.339296383948818, "null": 4.836856826828687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3832.json
index 72da57633d4..f314688d5a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3832.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3832.json
@@ -1 +1 @@
-{"ABACAVIR": 1.1332225434007197, "AFINITOR": 1.478775957182353, "AMINOSALICYLIC": 2.5190760484170025, "ASPARAGINASE": 6.178761764269764, "ATAZANAVIR": 2.52835779864938, "AVANDIA": 1.449783548260862, "BEDAQUILINE": 3.302878975172696, "BUSULFAN": 6.599491125356257, "BYETTA": 1.3643253383531944, "CICLOSPORIN": 2.874387740251926, "CRIXIVAN": 4.296713476066761, "CYTARABINE": 4.042389901088626, "DEXAMETHASONE": 2.2145979194151817, "EFAVIRENZ": 8.419660048653052, "EMTRICITABINE": 4.723320937088181, "ENBREL": 1.0455086452973197, "EPIVIR": 8.620628971074215, "EXJADE": 4.8437052723761695, "FASLODEX": 1.3590894409585086, "GANCICLOVIR": 3.848120487977617, "GLIVEC": 6.477623546234107, "IBUPROFEN": 3.1214779623115354, "ICLUSIG": 2.1754795957608533, "INSULIN": 2.3767663923348072, "INVIRASE": 20.812618482064707, "JAKAVI": 6.644585489172268, "JANUMET": 2.8402357754677285, "JANUVIA": 1.5319338505254425, "KALETRA": 4.778726089406887, "KYMRIAH": 3.8070722932632046, "LAMIVUDINE": 24.622710880008647, "LEVETIRACETAM": 1.9853602153562304, "LEVOFLOXACIN": 1.6634547318940742, "MEKINIST": 1.4603652679257768, "METHOTREXATE": 1.1636290067333392, "NEXAVAR": 1.416612017403328, "OCALIVA": 5.031470260330458, "OPSUMIT": 1.125162432955097, "OZEMPIC": 24.46817337092776, "PANTOPRAZOLE": 2.6609816737329206, "PEGASYS": 1.5814919856293153, "RITUXIMAB": 1.127311834588297, "SOLIRIS": 2.0192498845453515, "SOMATROPIN": 11.912783809452428, "SPRYCEL": 1.2977504685867127, "SUBOXONE": 1.083819991153191, "TASIGNA": 1.4699162388518134, "TRACLEER": 3.3072012109477136, "VFEND": 1.4792677286217653, "ZYPREXA": 1.7501916987708064, "null": 1.423252874455761}
\ No newline at end of file
+{"FYCOMPA": 30.46257916292862, "KEPPRA": 7.363409245311645, "LACOSAMIDE": 17.106628121265516, "LEVETIRACETAM": 8.602827307342709, "SUBOXONE": 5.4316405022887375, "null": 7.478723715983823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3833.json
index daa30bec46b..b1a45407098 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3833.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3833.json
@@ -1 +1 @@
-{"NEXAVAR": 6.587030998065674, "PEGASYS": 5.791091835619644, "SUTENT": 2.5091969475583973, "null": 1.5512971016791597}
\ No newline at end of file
+{"CYMBALTA": 12.384351457445456, "VAXZEVRIA": 0.6178021538544481, "null": 3.290437061208233}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3834.json
index 079ec59199f..87e990df424 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3834.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3834.json
@@ -1 +1 @@
-{"BUSULFAN": 8.959935614720834, "DAKLINZA": 35.420927228081126, "EPCLUSA": 24.785368289088403, "EXVIERA": 58.33212065210742, "HARVONI": 12.932037305789096, "NEXAVAR": 13.417094230003466, "OLYSIO": 50.17000056017976, "PEGASYS": 1.4618171686914243, "PEGINTERFERON": 10.755862477019967, "PEGINTRON": 5.677108487319266, "SOVALDI": 16.059846038349804, "null": 1.033603089584205}
\ No newline at end of file
+{"null": 3.59908058992106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3835.json
index 1ce49a18e33..1b5e5ff8a0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3835.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3835.json
@@ -1 +1 @@
-{"ADALIMUMAB": 6.724396334597728, "ANAKINRA": 129.96523550269524, "INFLIXIMAB": 320.4286824637925, "MERCAPTOPURINE": 283.7303273000464}
\ No newline at end of file
+{"ABILIFY": 0.8800663554107524, "ACLASTA": 5.578997902856047, "ARIPIPRAZOLE": 1.1404286052041546, "ARSENIC": 20.446490172271535, "BENZODIAZEPINE": 9.57965703394802, "BRINTELLIX": 0.8360288585970189, "BUDESONIDE": 0.15144354609389, "BUMETANIDE": 5.3303540269639145, "BUPIVACAINE": 15.95423029285921, "BUPRENORPHINE": 27.81516101832861, "BUVIDAL": 9.062927083250036, "CARBIDOPA": 2.353751551745864, "CHAMPIX": 1.7339995456044637, "CYMBALTA": 54.62378811252613, "DEXMEDETOMIDINE": 5.25714211792707, "DULOXETINE": 0.4831254398496277, "ENTACAPONE": 4.927621321142853, "EXFORGE": 0.3668947371903452, "FENTANYL": 9.796894066286365, "IBUPROFEN": 1.2206729626140391, "IRON": 1.924466591772606, "JAKAVI": 0.6565169677700767, "KEPPRA": 0.846708067898008, "LATUDA": 0.7898013436385262, "LEVETIRACETAM": 0.5266456823505284, "LEVODOPA": 4.847073654679399, "LEVOFLOXACIN": 0.2124975331435523, "LYRICA": 2.102057447103009, "MIDAZOLAM": 1.724778114437895, "NALMEFENE": 80.94441726232563, "NALOXONE": 8.763207396830463, "OLANZAPINE": 1.4353613731369146, "OPIOIDS": 27.80155307735634, "OXYBUTYNIN": 2.716469793406256, "PEGASYS": 0.1431595415598398, "PREGABALIN": 1.216093096510096, "PRIALT": 24.6190452188728, "ROTIGOTINE": 51.14117313413747, "SELINCRO": 169.31686542854504, "SUBOXONE": 61.85572902319647, "XYREM": 2.070564829784533, "ZYPREXA": 1.6348853626651745, "null": 2.021269483352029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3836.json
index 1a54beade45..5d37fbe9a7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3836.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3836.json
@@ -1 +1 @@
-{"ABACAVIR": 4.62450283413216, "ALEMTUZUMAB": 8.69857985981491, "ANAKINRA": 6.098629660157629, "ASPARAGINASE": 8.363037532467885, "AZATHIOPRINE": 8.039601851458428, "BEDAQUILINE": 15.39518701342432, "BUSILVEX": 56.23841639202787, "CICLOSPORIN": 9.01721319472986, "COMBIVIR": 9.84831592481146, "CYTARABINE": 4.6136682945475656, "DEXAMETHASONE": 2.696924539385122, "EFAVIRENZ": 11.98462843307787, "EPIVIR": 14.536455110451652, "IBUPROFEN": 2.703860227640599, "JAKAVI": 11.063642454228606, "KALETRA": 4.139265663746004, "LAMIVUDINE": 35.059602296950295, "LEVOFLOXACIN": 2.767922001183315, "ZYPREXA": 1.838638468091964, "null": 1.0682822877986244}
\ No newline at end of file
+{"ABILIFY": 5.642693544756414, "BENZODIAZEPINE": 31.410555451721237, "BUPRENORPHINE": 96.98426917810568, "BUVIDAL": 71.03492023019396, "CYMBALTA": 1.4783163689687928, "DEXMEDETOMIDINE": 20.131236801456076, "DULOXETINE": 2.7714501796719166, "FENTANYL": 5.198745511749201, "KEPPRA": 1.5250763230776687, "LEVETIRACETAM": 0.734851628180624, "LYRICA": 0.9824976281775032, "NALOXONE": 15.11581335382122, "NORVIR": 4.830257194988777, "OLANZAPINE": 3.5013214424624968, "OPIATES": 140.61201824392026, "OPIOIDS": 121.97395366582086, "SUBOXONE": 141.42027231905917, "VIGABATRIN": 41.80210790722083, "ZYPREXA": 2.6115860446176558, "null": 2.1826247867668886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3837.json
index 9aba0e93563..978a8eaa610 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3837.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3837.json
@@ -1 +1 @@
-{"ABIRATERONE": 27.09826907391346, "ACLIDINIUM": 21.478130648738183, "ADALIMUMAB": 1.1494096318934146, "AMIKACIN": 5.232923293963265, "AMINOSALICYLIC": 1.3537725914575187, "ANAKINRA": 21.505856923663856, "ANORO": 1.2358389049621077, "APTIVUS": 12.607378882023747, "ARAVA": 2.7113613139895683, "ASPARAGINASE": 11.069979152498458, "ATAZANAVIR": 1.4124313727084732, "AXITINIB": 14.272362363384111, "AZATHIOPRINE": 4.2104512197865045, "BEDAQUILINE": 11.143482604644063, "BEVACIZUMAB": 1.2121891770258073, "BLINATUMOMAB": 7.607816770877876, "BORTEZOMIB": 1.556228359970414, "BOSULIF": 4.842737385106275, "BRAFTOVI": 1.9536257988043344, "BUSULFAN": 2.431575437933876, "CABAZITAXEL": 5.925754882445448, "CABOMETYX": 3.343523441009091, "CAELYX": 3.693891311750168, "CANCIDAS": 2.823826544931943, "CAPECITABINE": 4.88377091229686, "CARMUSTINE": 4.956630564305426, "CASPOFUNGIN": 9.668283011896508, "CICLOSPORIN": 1.041703470667989, "CLOFARABINE": 7.595775336717903, "COBIMETINIB": 9.1304284538417, "COMBIVIR": 4.078806108719815, "COTELLIC": 3.9147110418945696, "CRESEMBA": 6.758688786864178, "CYTARABINE": 1.910675664993407, "DABRAFENIB": 2.916078764798514, "DASATINIB": 2.997220448582712, "DELAMANID": 5.850847030484843, "DELTYBA": 22.390869375384185, "DENOSUMAB": 3.856622085120218, "DEXAMETHASONE": 1.760489101119242, "DOCETAXEL": 1.4994291780991738, "EFAVIRENZ": 3.151962997086222, "EMTRICITABINE": 7.129990647187765, "ENBREL": 4.832846870144331, "ERLOTINIB": 94.12818719282616, "ESBRIET": 1.0820339239209702, "EXJADE": 1.6995205367226716, "FILGRASTIM": 4.74742296262051, "FULVESTRANT": 10.44203837597922, "GANCICLOVIR": 1.8122233119303792, "GEFITINIB": 12.271814291520244, "HALAVEN": 1.557446281083742, "IBRANCE": 1.0447854200595843, "ICLUSIG": 8.42043415909153, "IMATINIB": 5.330414666910616, "INLYTA": 5.658952619078822, "INVIRASE": 6.083870705208882, "IPILIMUMAB": 18.084465198137583, "IRESSA": 2.3314064927057734, "IRINOTECAN": 1.0095131757006917, "ISENTRESS": 1.265861914906654, "JAKAVI": 2.061009489696677, "KALETRA": 3.965942206987117, "KEYTRUDA": 2.220964745199124, "KISQALI": 31.71551463656383, "KYPROLIS": 3.050491475426421, "LAMIVUDINE": 7.983379440648861, "LEFLUNOMIDE": 1.66468382584245, "LEVETIRACETAM": 1.161807364152128, "LEVOFLOXACIN": 2.7849205834653707, "LOPINAVIR": 9.5417665369948, "LUMYKRAS": 50.388295503148655, "MEKINIST": 1.7779177738116492, "MERCAPTOPURINE": 11.327954826698743, "METHOTREXATE": 2.0846600525657006, "MULTAQ": 2.2396029478194133, "MYCOPHENOLATE": 1.2050036448506751, "NEVIRAPINE": 17.634299746053117, "NEXAVAR": 1.0164242155323575, "NILOTINIB": 12.271001638090668, "NORVIR": 2.034388551964605, "NOXAFIL": 9.44454040464298, "NUBEQA": 8.578679038591302, "OFEV": 3.9754868498428086, "ONCASPAR": 14.902398467486284, "OPDIVO": 3.769746093408006, "PAZOPANIB": 21.881884249347717, "PEMBROLIZUMAB": 6.909165705241249, "PEMETREXED": 8.437011960379898, "POSACONAZOLE": 8.128528294553155, "PROPRANOLOL": 2.061598014643246, "REMDESIVIR": 3.849337103795701, "REMICADE": 1.8840938863122267, "REYATAZ": 3.263681494975544, "RIBOCICLIB": 42.37642320431733, "SOMATROPIN": 13.493550296518764, "SORAFENIB": 5.478867204588851, "SOTORASIB": 44.974335675532025, "STIVARGA": 5.156989869061184, "SUTENT": 1.3920533598404152, "TACROLIMUS": 2.315869496282281, "TAGRISSO": 1.221719716726292, "TASIGNA": 4.890901328588043, "TEMODAL": 3.124515286193175, "TEMOZOLOMIDE": 3.594665722255572, "THIOTEPA": 15.106087171396371, "TRABECTEDIN": 19.16477250008546, "TRACLEER": 1.334220655892662, "TRISENOX": 7.840642177793671, "TRIUMEQ": 2.230755259211301, "VEKLURY": 5.511694354431929, "VEMURAFENIB": 10.494100004576406, "VFEND": 5.125883905380617, "VIRAMUNE": 17.558247300172678, "VORICONAZOLE": 24.86453081033385, "VOTRIENT": 13.828756504939784, "XALKORI": 10.712764797639675, "YERVOY": 6.895680990131609, "YONDELIS": 19.531439013723443, "ZELBORAF": 4.519386010526862}
\ No newline at end of file
+{"null": 0.9004185235913372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3838.json
index 838b01740c3..e994ddbd439 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3838.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3838.json
@@ -1 +1 @@
-{"null": 3.183863684710422}
\ No newline at end of file
+{"null": 2.571528168126639}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3839.json
index 06fc0735a6e..dbc5b8bd019 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3839.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3839.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 492.1708209018281}
\ No newline at end of file
+{"FENTANYL": 43.34640304021451, "null": 1.7945837226228631}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/384.json
index e3ef4d2f6cb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/384.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/384.json
@@ -1 +1 @@
-{"null": 1.5984532156507272}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3840.json
index c2cf42151ed..77a8b923cac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3840.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3840.json
@@ -1 +1 @@
-{"C1": 355.3965786839803, "CINRYZE": 786.3584686317851, "FIRAZYR": 243.83730034031265, "ICATIBANT": 148.55685883911383, "RUCONEST": 384.81613983022, "null": 9.62923465902985}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3841.json
index c94337e911c..dc811ee735d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3841.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3841.json
@@ -1 +1 @@
-{"null": 2.4674108568917084}
\ No newline at end of file
+{"EYLEA": 122.14711884575792, "ZOSTAVAX": 28.50303352185788, "null": 0.7030953682300184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3842.json
index 6e71d7a0433..b06bd4cf792 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3842.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3842.json
@@ -1 +1 @@
-{"null": 1.4295803886415972}
\ No newline at end of file
+{"ABATACEPT": 1.0604516330770284, "ABILIFY": 2.770251697501581, "ADALIMUMAB": 0.3431050229621811, "AERIUS": 1.8951802237110604, "AFINITOR": 0.4056341426941346, "AIMOVIG": 1.5287889766945, "AMGEVITA": 84.92637032176326, "ARAVA": 1.1043918041419236, "ARIPIPRAZOLE": 1.126107843787037, "AUBAGIO": 0.6958600139197016, "AVASTIN": 1.2378154036807238, "AZATHIOPRINE": 1.2130773689404086, "BENLYSTA": 0.9753581534892491, "BEOVU": 2.451368120452899, "BETMIGA": 6.721857575798488, "BRAFTOVI": 1.6596352367743212, "BRINTELLIX": 2.3305677580868176, "CAPECITABINE": 0.8688359172177905, "CHAMPIX": 0.6977271134681877, "CICLOSPORIN": 0.8424631886162408, "CIMZIA": 0.9292816994094404, "CLOPIDOGREL": 0.2759485429783064, "COAPROVEL": 1.4863653700678794, "COMIRNATY": 0.537905247359709, "COSENTYX": 2.0693219926019624, "CYMBALTA": 0.878564387978965, "DOCETAXEL": 1.7118599960139032, "DULOXETINE": 0.8467641455357214, "DUPIXENT": 5.376112115363782, "ELIQUIS": 0.5535966002643363, "ENBREL": 3.450327203075469, "ENTYVIO": 1.0109858433529746, "ETANERCEPT": 11.52595401748044, "EVISTA": 1.273938876691964, "EXFORGE": 0.6430489601717909, "EYLEA": 3.499352809416769, "FASLODEX": 1.1061074478532076, "FENTANYL": 0.2823518914231798, "FORSTEO": 0.3697117805875285, "FORXIGA": 0.9012898363321936, "FULVESTRANT": 1.148326173269537, "GARDASIL": 1.9160348976053443, "HUMALOG": 0.7687202472335557, "HUMIRA": 1.7043609340903432, "IBRANCE": 2.9496241876286198, "IBUPROFEN": 0.8066733925491786, "ICLUSIG": 3.6277618961705658, "IKERVIS": 34.10584149134583, "IMBRUVICA": 3.820337911851313, "INSULIN": 0.7810294098063569, "IPILIMUMAB": 1.2312100942884137, "IVACAFTOR": 77.82005651515487, "JAKAVI": 1.072575401346722, "JARDIANCE": 0.5154507901756559, "KAFTRIO": 7.324684094347828, "KEPPRA": 0.6795060729704825, "KEYTRUDA": 0.8393133558382775, "KISQALI": 1.5496573640055478, "LANTUS": 0.34789887965922, "LEFLUNOMIDE": 4.938555708644908, "LEVOFLOXACIN": 0.33291498309244, "LYRICA": 1.822335284389748, "MEKINIST": 0.9736228251095268, "METHOTREXATE": 1.801726014413509, "NEVANAC": 17.520869235384517, "NOT": 1.4290294590954853, "OLANZAPINE": 0.318535271119343, "OMALIZUMAB": 1.1992982358512303, "OPTIMARK": 0.7713818863005029, "OXYBUTYNIN": 5.631148755555689, "PEGASYS": 1.7413014023328366, "PEGINTERFERON": 1.9187828622369845, "PEGINTRON": 1.6776925287763689, "PEMBROLIZUMAB": 0.911352825211596, "RIBAVIRIN": 1.0254585907312397, "RITUXIMAB": 0.5604573958142699, "ROACTEMRA": 0.6894008610866158, "SAXENDA": 0.6957752335508001, "SHINGRIX": 0.7304600666494545, "SIMPONI": 0.7163402661356347, "SPIKEVAX": 0.4061670612646495, "SPRYCEL": 0.6378693920688192, "STELARA": 0.7217182254769358, "SUTENT": 0.913305062413493, "TAGRISSO": 2.448772686386256, "TASIGNA": 1.3519219872579626, "TOVIAZ": 10.75103012716396, "TOZINAMERAN": 1.077378588289064, "TRUVADA": 0.0876907604270346, "VAXZEVRIA": 0.5974716680923738, "VIAGRA": 0.5546754956098479, "XELJANZ": 1.707594713816035, "XOLAIR": 0.4691452176141432, "XTANDI": 0.4619311764462964, "XYREM": 2.591655121507472, "ZOSTAVAX": 6.099945537326991, "ZYPREXA": 0.4220805993368036, "null": 1.2378502136519949}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3843.json
index 535cb779d7c..d7c2c0de104 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3843.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3843.json
@@ -1 +1 @@
-{"COSENTYX": 32.82005858996298, "null": 1.0746098492797225}
\ No newline at end of file
+{"INVOKANA": 226.4341849909896, "null": 1.981967050653679}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3844.json
index 2cce0c07389..cb918b7b882 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3844.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3844.json
@@ -1 +1 @@
-{"BENLYSTA": 1.2918547215842282, "BOSULIF": 4.969237201429277, "BRAFTOVI": 2.599225140507091, "BYDUREON": 4.603402508756814, "BYETTA": 1.989503533441897, "CIMZIA": 2.609094590820507, "CLOPIDOGREL": 2.160702890925544, "COSENTYX": 1.5479270194114876, "ELIQUIS": 3.568909457307575, "ENBREL": 1.2258247074753672, "ENTYVIO": 1.4070521053258431, "ESBRIET": 2.7973538346685576, "FORSTEO": 1.9036140161943584, "HUMALOG": 2.6288768182658497, "HUMIRA": 1.729852640186941, "IBRANCE": 1.690927537019285, "IBUPROFEN": 1.21390975977008, "INLYTA": 2.3519276551861603, "INSULIN": 1.2704328462033705, "ISENTRESS": 6.804357810188088, "JAKAVI": 1.3177529632748624, "JANUMET": 1.9982476583659536, "JANUVIA": 1.6654573192576545, "LANTUS": 1.1577474889325436, "LYRICA": 5.406900300801098, "METHOTREXATE": 2.0302163710272287, "NAGLAZYME": 8.039563023613974, "NUCALA": 1.6366513632673507, "OPSUMIT": 1.513469113980197, "PLAVIX": 1.6257687247616817, "RAPAMUNE": 15.53870714872362, "RUBRACA": 6.633738957093603, "SIMPONI": 5.859566134299216, "STELARA": 5.810440246909886, "SUBOXONE": 1.3444760846490982, "SUTENT": 2.340069430387256, "SYNAGIS": 6.27137578201339, "TREMFYA": 4.0896738319595, "VIAGRA": 10.39443850190733, "XELJANZ": 5.032829561481814, "XOLAIR": 1.1339235182182972, "ZOSTAVAX": 3.438175435487462, "null": 1.427529872433756}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3845.json
index dbbfab98fde..bbdfcf855a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3845.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3845.json
@@ -1 +1 @@
-{"null": 2.6473914494403386}
\ No newline at end of file
+{"ABACAVIR": 0.2207540005897223, "ABILIFY": 0.2610014197976055, "ADALIMUMAB": 0.1404176099536033, "AERIUS": 1.207412733046801, "AFINITOR": 3.8170669719432686, "AIMOVIG": 0.5747517948771668, "ALIMTA": 0.3633362086642303, "AMINOSALICYLIC": 0.4232301627932948, "APIXABAN": 11.59042657341062, "ARANESP": 0.2184598036836424, "ARAVA": 0.6335003378431281, "AUBAGIO": 1.7305912594288315, "AVASTIN": 0.4632340470002754, "BEDAQUILINE": 1.512127549242748, "BENLYSTA": 1.0829963372190676, "BEVACIZUMAB": 0.5062614657936277, "BIKTARVY": 1.203522448051511, "BOSULIF": 2.222251118786424, "BRAFTOVI": 2.3646452371718434, "BRINTELLIX": 0.591237424983106, "BUDESONIDE": 0.5555950286744576, "BUPRENORPHINE": 0.2516554198999765, "BUSULFAN": 0.5061420270343348, "BYDUREON": 0.7218429746393632, "BYETTA": 0.4630082796956758, "CABOMETYX": 5.449332751267964, "CAPECITABINE": 1.9085419154211405, "CAPRELSA": 9.078980022181668, "CHAMPIX": 0.6319710039390903, "CICLOSPORIN": 0.5554909236678932, "CIMZIA": 0.8479899159065075, "CLOPIDOGREL": 0.5176001670082722, "COAPROVEL": 1.4061375592581098, "COMIRNATY": 0.2810372114397703, "CONTRAST": 21.77286039616827, "COSENTYX": 3.166996232207971, "CYMBALTA": 0.7679891531339026, "DABRAFENIB": 1.5463460130444664, "DEXAMETHASONE": 0.373164086246637, "DOCETAXEL": 0.3385500987925759, "DUPIXENT": 5.382447301237019, "ELIQUIS": 0.704774800531667, "EMPAGLIFLOZIN": 2.0056512877454336, "ENBREL": 0.6551937721156732, "ENTRESTO": 1.1344368754661631, "ENTYVIO": 1.8577521409687845, "ERBITUX": 6.654729430906476, "ERLEADA": 3.2248995108482728, "ESBRIET": 3.750508179036716, "EVEROLIMUS": 1.619943236992838, "EVISTA": 0.8116177920459969, "EXFORGE": 0.3618222445895894, "EXJADE": 0.3983940476667976, "FASENRA": 0.7999822777618643, "FASLODEX": 3.128372268005105, "FORSTEO": 0.5907213817445086, "FORXIGA": 1.4580538247558914, "FULVESTRANT": 3.124344516229024, "GARDASIL": 0.8976221148344863, "GLIVEC": 2.430498185370144, "HARVONI": 0.9485489600742352, "HERCEPTIN": 2.423594277497117, "HIZENTRA": 0.6322299406514684, "HUMALOG": 0.3321639209947899, "HUMIRA": 1.0677044288334254, "HYDROCORTISONE": 2.198940002968361, "IBRANCE": 6.865324103264642, "IBUPROFEN": 0.5250503768145213, "ICLUSIG": 8.639024360005838, "IMATINIB": 2.703836652337521, "INCIVO": 4.504093809964141, "INLYTA": 4.9808813461295225, "IPILIMUMAB": 1.0745812391240983, "IRESSA": 8.01838755447787, "IRINOTECAN": 3.8671319460963463, "JANUMET": 0.6374597349654424, "JANUVIA": 0.2694016613445549, "JARDIANCE": 1.128861975038511, "KAFTRIO": 0.998460693947618, "KEPPRA": 0.4447793263159997, "KEYTRUDA": 1.0063391661393213, "KISQALI": 6.189108316200277, "LANTUS": 0.2685951779575529, "LEMTRADA": 0.9469975356515614, "LEVETIRACETAM": 0.2609168701424231, "LEVOFLOXACIN": 0.2095592803196942, "LIXIANA": 1.4442751763318027, "LONSURF": 1.5774389254427876, "LYNPARZA": 1.1766572717653656, "LYRICA": 0.3747985254078064, "MEKINIST": 3.151904218956207, "MEPOLIZUMAB": 0.3026729129481059, "METHOTREXATE": 0.8377254748217556, "MICARDIS": 1.0379373827500815, "MMRVAXPRO": 0.8199188379574086, "NEULASTA": 0.8199485368102043, "NEXAVAR": 4.386110742939916, "NILOTINIB": 2.470110313204726, "NIMENRIX": 0.4386722357496589, "NINLARO": 2.0652185055844936, "NUCALA": 0.3805388678393476, "OFEV": 0.4848911856984852, "OLANZAPINE": 0.3394966175777915, "OLYSIO": 1.178629706444491, "OMALIZUMAB": 1.7426108424465383, "OPDIVO": 1.0677784975289268, "OPSUMIT": 0.202875403163946, "OPTIMARK": 9.036452805451052, "OXYBUTYNIN": 2.4386337866298984, "PEGASYS": 5.326728429618185, "PEGINTERFERON": 4.629284477818826, "PEGINTRON": 3.585168494221376, "PEMBROLIZUMAB": 1.4916791049521232, "PLAVIX": 0.2152451752211077, "PLEGRIDY": 0.6773240214130424, "PRIVIGEN": 0.7721328098896558, "REBETOL": 3.171585271804997, "RIBAVIRIN": 1.5001685335307948, "RINVOQ": 0.8164465181579992, "RITUXIMAB": 0.3527904844603266, "ROACTEMRA": 0.3878645072301996, "RUBRACA": 1.5438411595935386, "SHINGRIX": 0.5069353858604696, "SIMPONI": 1.0463742696633391, "SPIKEVAX": 0.2731842211596386, "SPRYCEL": 1.7916451870855783, "STELARA": 0.7239710247021991, "STIVARGA": 2.1585553927001384, "SUTENT": 9.181271766145445, "TAGRISSO": 9.05282648504712, "TASIGNA": 3.0858213151396257, "TOVIAZ": 1.499190992976986, "TOZINAMERAN": 0.6459626128406989, "TRAMETINIB": 11.59659415397186, "TRELEGY": 0.3790967723822812, "TREMFYA": 0.952065967048101, "TRODELVY": 2.035998854606293, "TRULICITY": 0.604239845898262, "VAXZEVRIA": 0.3329143907465383, "VECTIBIX": 12.709833565517892, "VFEND": 0.3806342723673357, "VOTRIENT": 2.319082014165, "XELJANZ": 0.6484979940883842, "XOLAIR": 0.9527549629628088, "XTANDI": 1.4371753469735145, "ZELBORAF": 7.936653768709182, "ZOSTAVAX": 0.9584959784060246, "ZYPREXA": 0.2031163560712987, "null": 0.862533047266673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3846.json
index 108e0448521..fdfd3a06b0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3846.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3846.json
@@ -1 +1 @@
-{"null": 3.053687468309727}
\ No newline at end of file
+{"ALEMTUZUMAB": 4.097864232999535, "AVAMYS": 1.4259742713438943, "BETMIGA": 5.28052200494966, "BRINTELLIX": 1.2075284246213291, "CAPECITABINE": 1.987046016522909, "CHAMPIX": 1.6735469490258228, "COMBIVIR": 2.482897451961384, "COMIRNATY": 0.7115420508549112, "CYMBALTA": 0.3811271998730712, "ELIQUIS": 0.278075933794002, "ENTRESTO": 0.8342218885308444, "EXFORGE": 1.665513306796057, "GALVUS": 5.062486347422186, "HUMALOG": 0.7385086502527248, "IBRANCE": 0.7167850275845755, "INCRUSE": 5.337692142926777, "INLYTA": 1.8298213194425648, "JARDIANCE": 0.622211535818447, "METHOTREXATE": 1.0570833232051489, "NEXAVAR": 0.5464122917683676, "OCRELIZUMAB": 2.178238103265466, "OFEV": 1.7406576328220322, "OMALIZUMAB": 2.7473402459910905, "PEGASYS": 1.0867889554797818, "PEGINTRON": 0.6427432084245073, "RELVAR": 9.737700678941952, "SPIKEVAX": 0.6126215003072043, "SUTENT": 0.2637565456157699, "TOVIAZ": 19.85959229979885, "TOZINAMERAN": 1.8175599233003668, "TRELEGY": 4.290083986585406, "VAXZEVRIA": 1.0939265593113592, "VOTRIENT": 2.1581839540940706, "XELJANZ": 1.3737119283698116, "XOLAIR": 0.5885445341591312, "null": 1.720269226624116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3847.json
index ee127128e66..b0c7925e37f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3847.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3847.json
@@ -1 +1 @@
-{"BYETTA": 13.749405786923012, "CIMZIA": 3.8876252647257368, "ELIQUIS": 1.531383597802475, "JANUMET": 14.619166618607922, "JANUVIA": 10.707654272441452, "LANTUS": 4.789465869472366, "OPSUMIT": 6.401501456095998, "PLAVIX": 2.7759190970341665, "TRELEGY": 14.37929895394199, "VOTRIENT": 5.59520254407644, "ZOSTAVAX": 6.873119302981594, "null": 1.438390471175909}
\ No newline at end of file
+{"PEGASYS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3848.json
index c1ed743becd..fcb7c3c4cfc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3848.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3848.json
@@ -1 +1 @@
-{"FORSTEO": 75.74112674475187}
\ No newline at end of file
+{"BYETTA": 82.77309843270505, "JANUMET": 70.27697403774542, "JANUVIA": 102.99031407032784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3849.json
index 6bec0e1542a..8f7c3942285 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3849.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3849.json
@@ -1 +1 @@
-{"COMIRNATY": 1.5155123232471337, "ZOSTAVAX": 14.271290395599584}
\ No newline at end of file
+{"null": 5.477537162190193}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/385.json
index 805d2500bb1..d8e13a1bcac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/385.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/385.json
@@ -1 +1 @@
-{"INCIVO": 156.10212426211726, "JARDIANCE": 2.769210884809375, "PEGASYS": 28.45281085338077, "PEGINTERFERON": 67.68052608117532, "PEGINTRON": 3.9272887637429887, "RIBAVIRIN": 9.494457793957295, "null": 1.336857798583155}
\ No newline at end of file
+{"BRIDION": 229.77927191725504, "FENTANYL": 104.3362260798244, "null": 1.821856242687136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3850.json
index 428c93eac22..9085b02b2cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3850.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3850.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3242895320335208, "ENBREL": 3.065783985862817, "RINVOQ": 36.00855282893569, "SHINGRIX": 17.45890440622003, "STELARA": 2.918707663223381, "XELJANZ": 5.476988279062687, "ZOSTAVAX": 13.007494699000096}
\ No newline at end of file
+{"null": 6.678337061353202}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3851.json
index 47efbbfce7a..c6a740acc54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3851.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3851.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 50.22142242801687, "ARIPIPRAZOLE": 5.0937355205259935, "ASPARAGINASE": 4.361995427065136, "ATAZANAVIR": 9.305501205112126, "AZATHIOPRINE": 6.36213953867438, "BUSULFAN": 15.249599885558348, "CELLCEPT": 3.036142562647808, "CICLOSPORIN": 3.907995052831402, "COMIRNATY": 1.458690643470525, "COSENTYX": 1.2993632177539165, "CYTARABINE": 5.380678817899063, "DEXAMETHASONE": 1.0469811473868935, "GARDASIL": 1.0402454925401068, "HUMALOG": 3.045355627835913, "ISENTRESS": 6.228646950000963, "MAVENCLAD": 13.868369911307, "METHOTREXATE": 3.795340454575125, "PEGINTRON": 1.8573947591484203, "RINVOQ": 17.119894279312625, "RITUXIMAB": 2.654232040550954, "RUXOLITINIB": 9.455190357220689, "SHINGRIX": 8.856628670201761, "SOLIRIS": 1.5495944537158544, "STELARA": 1.1123203237732704, "XELJANZ": 1.127004464223764, "XOLAIR": 1.165581215856921, "ZOSTAVAX": 8.116162279543603}
\ No newline at end of file
+{"null": 1.3658892787318906}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3852.json
index ebc284937f7..07d7b1317f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3852.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3852.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 33.339552058082646}
\ No newline at end of file
+{"null": 0.899561421132194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3853.json
index c571fc569b0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3853.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3853.json
@@ -1 +1 @@
-{"HUMIRA": 360.22519557019314}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3854.json
index 4776a2249e1..9f735ec6bac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3854.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3854.json
@@ -1 +1 @@
-{"COMIRNATY": 2.955895917989765, "SPIKEVAX": 1.6170912957126131}
\ No newline at end of file
+{"BYETTA": 41.2908445716403, "CYTARABINE": 35.94525437583702, "null": 0.3969928511958395}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3855.json
index 0ee850e4d7a..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3855.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3855.json
@@ -1 +1 @@
-{"AIMOVIG": 1.006121226485165, "ALEMTUZUMAB": 2.474231961773608, "AUBAGIO": 1.59689239938296, "BENLYSTA": 3.657840266375231, "BUSULFAN": 2.6719051513592813, "CELLCEPT": 4.878012250783681, "CICLOSPORIN": 3.642620548615077, "CIMZIA": 1.9942364006977729, "COMBIVIR": 3.960215327357408, "COMIRNATY": 1.6875062487224244, "COSENTYX": 1.898993888555306, "CYMBALTA": 1.0024835877347569, "CYTARABINE": 1.3617929308156218, "EPIVIR": 6.384761337558008, "JAKAVI": 4.387887526162106, "KALETRA": 2.8073357954289966, "METHOTREXATE": 2.6482337682729367, "PEGINTERFERON": 1.7154036413962264, "RINVOQ": 21.3461419727408, "ROACTEMRA": 3.0791500327288777, "SHINGRIX": 7.40865426325525, "SIMPONI": 6.508781222857118, "SPIKEVAX": 1.1711851749049762, "STELARA": 3.8324399324179312, "TREMFYA": 4.535238015381255, "VAXZEVRIA": 1.123527381494989, "XELJANZ": 2.4900287144035707, "ZOSTAVAX": 3.3273371846989366}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3856.json
index f6c05b04bb6..40eb4b47790 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3856.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3856.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 1.539413839453601, "ANAKINRA": 2.848264339664613, "AZATHIOPRINE": 1.0333353035215929, "BENLYSTA": 1.30960530818724, "CELLCEPT": 2.003161757855574, "CIMZIA": 1.3610423559591176, "CLADRIBINE": 1.4532416075650283, "CLOFARABINE": 1.4186153456539452, "COMIRNATY": 2.243090055306674, "ELASOMERAN": 8.16818884785346, "ENBREL": 1.6820188874432795, "ERELZI": 1.4193680459240443, "ETANERCEPT": 1.7563861269944547, "FASENRA": 1.356489783809533, "GOLIMUMAB": 1.7722088662887352, "INVIRASE": 1.5081249419542748, "JAKAVI": 3.777462339358639, "KESIMPTA": 1.2407800114732683, "LEMTRADA": 1.9311846839618367, "LUPKYNIS": 1.3180956857825217, "MAVENCLAD": 6.673886345570021, "MELPHALAN": 1.168541953486569, "MERCK": 17.952416527121674, "NOT": 2.548771515691624, "OLUMIANT": 6.555151153543076, "OZEMPIC": 1.3742330706038348, "REMICADE": 1.2898075830160018, "RINVOQ": 10.37854035603726, "RITUXIMAB": 1.1415203574348034, "ROACTEMRA": 2.9809067398324367, "RUXOLITINIB": 1.261866943020305, "SHINGRIX": 40.42503127967853, "SIMPONI": 1.813373672043992, "SPIKEVAX": 1.27990204605908, "STELARA": 1.417880904892384, "TOFACITINIB": 3.9688817048490073, "TOZINAMERAN": 1.1202737526882562, "UPADACITINIB": 8.289182462460916, "VELCADE": 1.523509173774115, "XELJANZ": 3.829311634892809, "ZOSTAVAX": 50.55248663934648}
\ No newline at end of file
+{"AVASTIN": 34.40179005138358, "BEDAQUILINE": 34.31028382411531, "KEYTRUDA": 9.332353723677937, "LENVIMA": 42.479587530942695, "STIVARGA": 17.84452260203771, "SUTENT": 2.306369514102645, "null": 0.6854769905243662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3857.json
index 5fdba160293..e06f8b133fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3857.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3857.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3413355819420414, "SHINGRIX": 36.22663769366602, "ZOSTAVAX": 20.23082701366594}
\ No newline at end of file
+{"null": 1.4702359818995074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3858.json
index d4212f42edc..a8b10bf8782 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3858.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3858.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 24.0122824094106, "CELLCEPT": 19.49743717543661, "CICLOSPORIN": 5.826038030094606, "RINVOQ": 15.486438901225457, "SHINGRIX": 10.525816003714905, "XELJANZ": 4.146013822175415, "ZOSTAVAX": 83.19416761622605}
\ No newline at end of file
+{"null": 1.437501714802899}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3859.json
index e6dcb4cf9e3..c1bbb4b698c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3859.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3859.json
@@ -1 +1 @@
-{"ZOSTAVAX": 41.1470387436672}
\ No newline at end of file
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/386.json
index 03b778baaf1..b64d831ae3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/386.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/386.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"MEPOLIZUMAB": 95.04338039409016, "METHOTREXATE": 339.4038530446654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3860.json
index 6e0f3ef829e..9d6c49c604c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3860.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3860.json
@@ -1 +1 @@
-{"COMIRNATY": 1.912633138641914}
\ No newline at end of file
+{"ADALIMUMAB": 0.1702565923501166, "ARAVA": 0.6477747798906252, "AVASTIN": 3.3192842900964306, "BRILIQUE": 7.85658530861452, "BYETTA": 3.5073088472060245, "CELLCEPT": 2.6551684445658026, "CICLOSPORIN": 0.9000321128662928, "CLOPIDOGREL": 14.1316768104444, "COMIRNATY": 0.0344007417798563, "DARUNAVIR": 24.337162714480083, "DEXAMETHASONE": 1.023493133396449, "ELIQUIS": 3.831347350277895, "EXJADE": 5.436534657061409, "IBUPROFEN": 3.2477249138437525, "JAKAVI": 1.5678854519042815, "JANUMET": 1.6967443011455932, "JANUVIA": 3.7594226531965895, "JARDIANCE": 0.6987042870366741, "KEYTRUDA": 2.498005101281809, "LENVIMA": 4.282201277694157, "LEVOFLOXACIN": 0.8448686373567998, "LIXIANA": 4.25094939236723, "MEKINIST": 1.8842308402958716, "NEXAVAR": 1.6519670680009275, "OPDIVO": 2.243668147278874, "PANTOPRAZOLE": 3.5516158389963133, "PEGASYS": 0.5058128965109858, "PLAVIX": 12.41165459692926, "SUTENT": 1.2319220945776552, "TAMIFLU": 2.650652489980656, "TICAGRELOR": 15.889728071557718, "VOTRIENT": 1.7401765809713197, "XTANDI": 0.9751081453063848, "null": 1.9657563506171989}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3861.json
index 70efe343fae..0be9f0300c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3861.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3861.json
@@ -1 +1 @@
-{"CELLCEPT": 23.729785859800128, "COMIRNATY": 1.0148165666454203, "ZOSTAVAX": 12.96453523217852}
\ No newline at end of file
+{"AVASTIN": 5.802591850002765, "BRILIQUE": 5.748727404698567, "CLOPIDOGREL": 21.62159635068214, "COMIRNATY": 0.0271352663002754, "EFIENT": 25.76456135924674, "ELIQUIS": 5.809898943996736, "EXJADE": 3.8422594154079657, "IBUPROFEN": 3.697066731239334, "LENVIMA": 8.061933411146926, "LIXIANA": 8.003096730405808, "NEXAVAR": 2.3628842627026434, "PLAVIX": 28.28255813912088, "TAMIFLU": 3.357202942013878, "TICAGRELOR": 32.86101281959504, "XARELTO": 14.474002180915386, "null": 1.7130556973048008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3862.json
index 1e35db19395..aefb1983396 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3862.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3862.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9517678822153532, "SHINGRIX": 32.34507630398697, "TOZINAMERAN": 1.9099136768094476, "ZOSTAVAX": 66.95677680885454}
\ No newline at end of file
+{"ABATACEPT": 28.05787125401948, "ACETAMINOPHEN": 67.64089812316634, "ADALIMUMAB": 45.01826715109623, "AMINOSALICYLIC": 0.921426047821064, "APREMILAST": 23.935253822625956, "APREPITANT": 90.4668098392763, "ARAVA": 34.06516524957513, "AVASTIN": 0.9903641070292466, "CIMZIA": 4.919323499046497, "COSENTYX": 2.06391950965014, "ERELZI": 12.148935606893485, "EXJADE": 0.4816193550201349, "HUMIRA": 1.5842949366845664, "HYDROCORTISONE": 1.7081694163536394, "MYCOPHENOLATE": 3.714255700967463, "RITUXIMAB": 4.013334017329695, "null": 0.0613668352666214}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3863.json
index fb528357e81..4f75faa17c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3863.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3863.json
@@ -1 +1 @@
-{"COMIRNATY": 2.2601676613157653, "SHINGRIX": 26.978841374842805, "SPIKEVAX": 1.4476517519033627, "TOZINAMERAN": 1.8469353333441336, "ZOSTAVAX": 59.07217233105953}
\ No newline at end of file
+{"ADCIRCA": 24.60719711684903, "BYETTA": 13.78139755827861, "CHAMPIX": 1.5075632956929856, "CLOPIDOGREL": 10.94350852739483, "COMIRNATY": 0.0762736774883033, "DACLATASVIR": 42.56792082718861, "ELIQUIS": 1.5106628753224836, "FENTANYL": 2.5512726011700244, "INFLIXIMAB": 19.40263865414012, "IPILIMUMAB": 20.940303671947945, "JANUMET": 3.393304223382985, "JANUVIA": 2.692060788775488, "KEYTRUDA": 2.726024683281772, "METHOTREXATE": 4.292636553809561, "OPDIVO": 8.178438769507647, "PLAVIX": 5.497788573664943, "SUTENT": 1.375259881146429, "null": 1.1702252277103269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3864.json
index b6dff508694..c2e817acb5f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3864.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3864.json
@@ -1 +1 @@
-{"null": 3.38955926305894}
\ No newline at end of file
+{"COMIRNATY": 0.5619329119757608, "SPIKEVAX": 0.5974871449470112, "VAXZEVRIA": 0.7145632296836494, "null": 0.7179149906336206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3865.json
index 383d77d2688..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3865.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3865.json
@@ -1 +1 @@
-{"NORVIR": 182.35772313239215, "null": 1.6834697008824535}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3866.json
index f041ef176c3..3edefe048a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3866.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3866.json
@@ -1 +1 @@
-{"null": 4.198672806064916}
\ No newline at end of file
+{"null": 3.930391680952254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3867.json
index 635864239d9..496187847b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3867.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3867.json
@@ -1 +1 @@
-{"ACTOS": 6.222411685293688, "ADENURIC": 5.58467613474207, "ATAZANAVIR": 3.607914616019385, "AVAMYS": 6.146156286920398, "BRILIQUE": 1.2494825657740734, "BUDESONIDE": 2.247945742895284, "BYDUREON": 2.074392765640138, "BYETTA": 4.68797654007014, "CLOPIDOGREL": 1.3726663177255711, "DENOSUMAB": 7.604055509230259, "ELIQUIS": 1.2880547422148003, "ENBREL": 1.2129104265374269, "ESBRIET": 2.212733849698695, "EXFORGE": 1.4903924384336174, "FASLODEX": 1.026441025638548, "FORSTEO": 3.7366287009973895, "IBUPROFEN": 1.3367774586421175, "IRBESARTAN": 2.240430234191863, "JANUMET": 6.072594581658309, "JANUVIA": 6.082942835515455, "LYRICA": 1.1005087133872355, "METHOTREXATE": 2.8967052859513065, "OCRELIZUMAB": 12.404243996863334, "OMALIZUMAB": 1.5285429427478845, "PANTOPRAZOLE": 1.4539579725060328, "PLAVIX": 2.2823871712581205, "SEEBRI": 39.99138034595639, "SPIRONOLACTONE": 9.265685885806302, "SPRYCEL": 1.053509905342771, "XELJANZ": 1.0310783653080882, "XOLAIR": 1.597372685759248, "ZOSTAVAX": 3.074170269806032, "null": 3.717612659088181}
\ No newline at end of file
+{"ACLIDINIUM": 82.26474012607873, "BIKTARVY": 35.86342570000992, "COLLAGENASE": 3283.2422052339657, "COMIRNATY": 0.2072391737147815, "XIAPEX": 1015.0574975032964, "ZOSTAVAX": 4.9099012234048045, "null": 1.259947412774528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3868.json
index 0db2a4526df..444eb1152f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3868.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3868.json
@@ -1 +1 @@
-{"ADCIRCA": 8.123789971034313, "ALIMTA": 5.019894154420486, "AVASTIN": 4.821485675719646, "BEDAQUILINE": 6.972485855067602, "BEVACIZUMAB": 7.797453592364011, "BYDUREON": 2.7150321398576494, "CAPECITABINE": 3.80699673623874, "DEXAMETHASONE": 3.0719607239476834, "EMEND": 36.49961914269803, "IRINOTECAN": 5.818771108992019, "JANUMET": 1.37971970561548, "KEPPRA": 1.5496156003630783, "MIDAZOLAM": 2.8204241834172783, "NEXAVAR": 3.107871733802602, "OPDIVO": 1.8395303689476343, "SAXENDA": 3.8060620152388194, "SUTENT": 5.597661066415836, "TACROLIMUS": 7.0034951531256535, "TEDUGLUTIDE": 52.586467848788864, "TRULICITY": 6.6596385647474845, "VFEND": 1.3826012273109505, "VICTOZA": 4.322369355181453, "VOTRIENT": 1.8543602185095016, "null": 2.697561980184705}
\ No newline at end of file
+{"ACLIDINIUM": 4289.238193960354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3869.json
index 57569b060df..103012a7c01 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3869.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3869.json
@@ -1 +1 @@
-{"ADALIMUMAB": 8.452485382796315, "CELLCEPT": 5.101948365812859, "CIMZIA": 9.4000427911574, "COSENTYX": 23.246949127168527, "ENTYVIO": 7.241624454815877, "ERTAPENEM": 209.6121553729037, "GARDASIL": 2.876777436521344, "HUMIRA": 47.26125021553986, "REMICADE": 20.12228760304287, "STELARA": 6.703902584385763}
\ No newline at end of file
+{"COMIRNATY": 1.3913697540835566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/387.json
index c3d9becbc4e..88dfddcdf21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/387.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/387.json
@@ -1 +1 @@
-{"null": 1.1464456165419163}
\ No newline at end of file
+{"ABILIFY": 58.8531046935702, "ARIPIPRAZOLE": 85.09058944866679, "BRINTELLIX": 4.58741975998071, "CARIPRAZINE": 79.92834982480295, "CIRCADIN": 9.333845112202145, "COMIRNATY": 0.0251851410298533, "CYMBALTA": 3.070550751610774, "DULOXETINE": 5.006365863085079, "INVEGA": 12.6583957862369, "LATUDA": 50.277405798980354, "LEVETIRACETAM": 1.6062336059335347, "LURASIDONE": 38.58075478871739, "LYRICA": 0.7113793885569484, "MELATONIN": 4.803322928830559, "OLANZAPINE": 21.536792327260116, "PROPRANOLOL": 6.0956223297312, "REAGILA": 204.8978556760539, "RISPERIDONE": 5.32539636822857, "SYCREST": 54.24927311229766, "VAXZEVRIA": 0.0434194754999332, "VORTIOXETINE": 18.435545141214945, "ZYPADHERA": 29.23638263451846, "ZYPREXA": 17.46367824396271, "null": 1.825634401692392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3870.json
index 2116423a595..d0d6bdc2e57 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3870.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3870.json
@@ -1 +1 @@
-{"null": 6.536504304697172}
\ No newline at end of file
+{"ABILIFY": 4.108262861012761, "ANORO": 778.5265350418694, "APIXABAN": 110.07928200261917, "AVAMYS": 33.799660249830936, "AZATHIOPRINE": 33.73311830011506, "COMIRNATY": 0.0496861301063066, "OMALIZUMAB": 33.67648981589529, "PANTOPRAZOLE": 25.49391377440144, "UMECLIDINIUM": 89.7487501433793, "null": 0.1403248216696098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3871.json
index 30fea55b174..3d10e40cbce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3871.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3871.json
@@ -1 +1 @@
-{"ABACAVIR": 4.3398256019239785, "ARIPIPRAZOLE": 23.527148350132716, "AVANDIA": 5.018453519998397, "ENTRESTO": 13.061225053515928, "OLANZAPINE": 3.141827113146035, "ZYPREXA": 6.47134708074725, "null": 1.4731437203725302}
\ No newline at end of file
+{"null": 1.006633644640497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3872.json
index 18be3d29c8e..41336198a9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3872.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3872.json
@@ -1 +1 @@
-{"CYMBALTA": 4.294792470125227, "RINVOQ": 23.937290253463665, "ROACTEMRA": 25.15007310612645}
\ No newline at end of file
+{"COMIRNATY": 0.9842491818222268, "null": 0.7792448177656844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3873.json
index 9fbcb654807..a8a9090bc98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3873.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3873.json
@@ -1 +1 @@
-{"ELIQUIS": 57.879488600570006}
\ No newline at end of file
+{"AMIKACIN": 3.7800801003837576, "ANAGRELIDE": 73.24290938521547, "AUBAGIO": 2.1201063919752463, "CAPECITABINE": 1.926763297514936, "CICLOSPORIN": 0.4125907381859137, "COMIRNATY": 3.0107817784583637, "COSENTYX": 0.5644815768836607, "GARDASIL": 3.5214856124315714, "LANTUS": 0.692066460037383, "LEVOFLOXACIN": 0.6520101897680386, "MMRVAXPRO": 0.6907183374058571, "MODERNA": 1.1727265122016055, "NEXAVAR": 0.6714214720817854, "PEGASYS": 0.2938367391735623, "SHINGRIX": 2.888776473596866, "SIMPONI": 0.7075893755665915, "SPIKEVAX": 1.2394799005291774, "STIVARGA": 1.103367830460705, "SUTENT": 0.4262576600202235, "THALIDOMIDE": 4.974378184157472, "TOZINAMERAN": 0.3196608395296463, "TWINRIX": 5.055151893154581, "VAXZEVRIA": 0.8641495009426854, "ZOSTAVAX": 0.5005073391348537, "null": 0.8123092575077224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3874.json
index f5e11d10d01..5f8978fe472 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3874.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3874.json
@@ -1 +1 @@
-{"SUBOXONE": 51.08161035876591}
\ No newline at end of file
+{"null": 12.763342336763872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3875.json
index 3651bc2e128..db7aae691de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3875.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3875.json
@@ -1 +1 @@
-{"null": 1.9278588677871185}
\ No newline at end of file
+{"null": 1.358446126336236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3876.json
index 180ecdaa52b..33064365cb5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3876.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3876.json
@@ -1 +1 @@
-{"INFANRIX": 392.15024004063065, "null": 1.760684130622174}
\ No newline at end of file
+{"ABACAVIR": 0.4331854040392682, "ABILIFY": 1.8102572098680128, "AERIUS": 0.9651836139907588, "AFINITOR": 0.2369146895536173, "AIMOVIG": 0.5409671470646554, "ALEMTUZUMAB": 0.8047397726510553, "ALIMTA": 0.3679185773206558, "ALISKIREN": 33.22336776202583, "APIDRA": 0.3267625878485701, "APIXABAN": 0.1616947001203006, "ARANESP": 0.3431422559050496, "ARAVA": 0.0468869823733703, "ARIPIPRAZOLE": 2.416663726769768, "ATRIPLA": 0.026478846003447, "AUBAGIO": 1.382473957004405, "AVANDIA": 0.3083080830684088, "AVASTIN": 0.4436515602081404, "AZILECT": 5.983267079969332, "BENLYSTA": 0.2406419995928957, "BENRALIZUMAB": 3.1681000635322896, "BETAFERON": 0.926486275571058, "BEVACIZUMAB": 0.4482810418088639, "BIKTARVY": 0.4008970585706213, "BRILIQUE": 0.6198786343246698, "BRINTELLIX": 0.6274496892545476, "BRIVARACETAM": 3.353894036007678, "BRIVIACT": 1.4840408429372889, "BUPIVACAINE": 0.7369825975151694, "BUPRENORPHINE": 2.546728590505028, "BYDUREON": 0.5769444598765837, "BYETTA": 0.2030847071365857, "CABOMETYX": 0.5297912747202819, "CANNABIDIOL": 4.220369824274967, "CAPECITABINE": 1.16933565924476, "CELLCEPT": 0.184232081499196, "CHAMPIX": 1.770234071876231, "CICLOSPORIN": 0.7402666125644499, "CIMZIA": 0.1795656391342553, "CLOPIDOGREL": 0.8987348865906304, "COMIRNATY": 0.4399006918071997, "COSENTYX": 0.1699585270211073, "CYMBALTA": 1.2042245621231145, "CYTARABINE": 0.976341085294076, "DEXAMETHASONE": 0.6615657663517173, "DULOXETINE": 1.486515078850213, "EFAVIRENZ": 1.3132526026272155, "ELIQUIS": 0.8730902965449723, "EMTRIVA": 3.73013279505712, "ENOXAPARIN": 1.3449988093971832, "ENTRESTO": 0.2846630110100963, "EPIVIR": 1.5424026227622454, "EUCREAS": 1.4403196633378437, "EXFORGE": 0.5271039251080539, "EXJADE": 0.1978543198589333, "EYLEA": 1.7199457653239387, "FAMPYRA": 1.603791676103255, "FASENRA": 0.4444742922726469, "FASLODEX": 0.2498253515993045, "FENTANYL": 2.470457771312636, "FIRDAPSE": 1.7435303034040817, "FORSTEO": 0.1312620819145051, "FORXIGA": 0.2729450313908236, "FYCOMPA": 7.500747393907536, "GARDASIL": 0.9404594142191348, "GLIBENCLAMIDE": 1.6689582009955672, "HARVONI": 0.4710682542482952, "HIZENTRA": 0.4562373846705847, "HUMALOG": 0.6047122374467201, "HUMAN": 0.5306676928281907, "HYDROCORTISONE": 0.4172826483848189, "IBRANCE": 0.1407926858420407, "IBUPROFEN": 1.1186333563495596, "INLYTA": 0.3215358379234126, "INSULIN": 0.4104690797900221, "INTELENCE": 3.421208629107179, "IRBESARTAN": 1.1123180461892537, "IRINOTECAN": 7.501021096371077, "JAKAVI": 0.245414287136563, "JANUMET": 0.4815547292334182, "JANUVIA": 0.3831164028805296, "JARDIANCE": 0.0965645661640094, "KALETRA": 0.7334073111837972, "KEPPRA": 2.519768671487279, "KEYTRUDA": 0.4623723233113286, "KYMRIAH": 1.2166280895248314, "LACOSAMIDE": 2.302824382642821, "LANTUS": 0.8538823755878779, "LATUDA": 2.317266486983779, "LEFLUNOMIDE": 0.7806761636453392, "LEMTRADA": 0.99667431396524, "LEVETIRACETAM": 1.811238677126468, "LEVODOPA": 2.453991309162341, "LEVOFLOXACIN": 0.3562697424680307, "LIXIANA": 0.5874981602069589, "LYRICA": 2.7875695280969293, "MEKINIST": 0.7402708657621221, "MELATONIN": 1.2396738521960649, "METFORMIN": 1.2297830458457784, "METHOTREXATE": 0.2077676175857409, "MICARDIS": 0.5165543117002221, "MIDAZOLAM": 0.7883933958611956, "MODERNA": 0.1541926964375861, "NALOXONE": 4.290598408555982, "NEXAVAR": 0.3701584469786491, "NILOTINIB": 1.5586967505031115, "NOT": 0.7277779635213828, "NOVONORM": 3.80569693573888, "OCRELIZUMAB": 0.5307910081137927, "OLANZAPINE": 4.363034129231791, "OMALIZUMAB": 0.477075005771037, "OPSUMIT": 0.2610211659782832, "OXYBUTYNIN": 2.1413836295883426, "PANTOPRAZOLE": 0.8347565114060383, "PEGASYS": 0.3547530572835523, "PEGINTRON": 0.8660873831710024, "PLAVIX": 0.9332748742838288, "PREGABALIN": 4.997138654675177, "RASILEZ": 0.8985957515281624, "RINVOQ": 0.3668166149935276, "RISPERIDONE": 4.998529316077903, "RITUXIMAB": 0.4694541133060204, "ROACTEMRA": 0.2447631532562102, "SHINGRIX": 0.6434038754334411, "SILDENAFIL": 0.7988109024985399, "SIMPONI": 0.1434589686579557, "SOLIRIS": 0.3678039004165317, "SPIKEVAX": 0.4511140533936277, "STALEVO": 1.2684708139463658, "STELARA": 0.4498414346350857, "STIVARGA": 0.2834803116320291, "SUBOXONE": 0.9309801207017157, "SUTENT": 0.2757657303111284, "SYCREST": 11.53932727711263, "TAMIFLU": 1.0759891521764506, "TASIGNA": 1.2658889002388056, "THALIDOMIDE": 1.0089258690588887, "TOZINAMERAN": 1.0299022299796174, "TRULICITY": 0.245800676885382, "VALDOXAN": 6.116331297362772, "VAXZEVRIA": 0.506042843896126, "VFEND": 0.754770232575651, "VIAGRA": 0.4329371523866654, "VIMPAT": 2.353309594413144, "VOTRIENT": 0.5281604403483232, "XARELTO": 0.6998532533361603, "XELJANZ": 0.1721847411769594, "XOLAIR": 0.4163108248200576, "XTANDI": 0.4234552829085505, "YESCARTA": 0.8212951902403275, "ZOSTAVAX": 0.5224850296231682, "ZYPADHERA": 58.70617919143494, "ZYPREXA": 2.852999275591684, "null": 2.1480180756272347}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3877.json
index 57635a8d70a..1f9a44bdc29 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3877.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3877.json
@@ -1 +1 @@
-{"CICLOSPORIN": 7.195542713521421, "GLYCOPYRRONIUM": 109.3371858324765, "NEXAVAR": 8.536389729584071}
\ No newline at end of file
+{"AMINOSALICYLIC": 9.295240045622233, "BUSULFAN": 43.37323540920034, "COMIRNATY": 0.2914036155240718, "LEVOFLOXACIN": 20.047662924042097, "SPIKEVAX": 0.2364795800205504, "null": 2.3424832500177426}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3878.json
index 36f89e56b68..e416b5b0583 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3878.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3878.json
@@ -1 +1 @@
-{"ABATACEPT": 9.4061206372515, "ADALIMUMAB": 6.0346478264545, "APREMILAST": 19.70174355969116, "ARAVA": 16.904942103738954, "ATRIPLA": 10.137294714304495, "BENLYSTA": 2.5896586722377584, "CAPECITABINE": 1.2815993267408718, "CIMZIA": 3.717593617854537, "ENBREL": 2.256174423315356, "EVISTA": 3.948220905738071, "FORSTEO": 3.598758391775771, "HUMIRA": 1.5001422282153194, "HYDROCORTISONE": 5.247101754103886, "JANUMET": 1.4819538626093527, "JANUVIA": 1.2509146112409764, "JARDIANCE": 1.1354262727823354, "LANTUS": 1.360468002875732, "LEVEMIR": 1.745547253807107, "OMALIZUMAB": 1.1615837216378668, "OPSUMIT": 1.4003296808407488, "SIMPONI": 7.95387826420482, "STELARA": 1.9751278623068305, "STRIBILD": 6.665369088413817, "TRELEGY": 3.281440012979272, "TRUVADA": 6.418942258890757, "VIREAD": 1.9103647093611624, "XELJANZ": 2.7120839709362485, "ZOSTAVAX": 4.230668839777007}
\ No newline at end of file
+{"null": 3.717696276768264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3879.json
index eb6af6afef9..7e544301cd3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3879.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3879.json
@@ -1 +1 @@
-{"ARAVA": 4.3920892718757925}
\ No newline at end of file
+{"AIMOVIG": 7.026971793146089, "COMIRNATY": 0.259695874710889, "ELIQUIS": 2.287089707084687, "ENTYVIO": 12.189379562210648, "GARDASIL": 1.557564057561343, "HUMIRA": 9.944315328606624, "IBRANCE": 1.344193225549219, "PEGASYS": 3.7787155897268376, "SPIKEVAX": 0.284149879231044, "SUTENT": 3.758019712574744, "TOZINAMERAN": 0.2913953844001714, "VAXZEVRIA": 0.2472248831941762, "XELJANZ": 1.930951928864407, "null": 1.3555317353356628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/388.json
index 8736ac0fc84..20399048703 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/388.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/388.json
@@ -1 +1 @@
-{"null": 2.2651680013742945}
\ No newline at end of file
+{"CARBIDOPA": 36.96324373022631, "CLOPIDOGREL": 2.233863117215472, "COMIRNATY": 0.0842547387988213, "COMTAN": 135.48880027440038, "ENTACAPONE": 90.16038367664906, "ENTRESTO": 4.05736747784321, "IBUPROFEN": 3.960895766381687, "KEPPRA": 1.620318625431478, "LANTUS": 1.6937959610207485, "LEVODOPA": 72.04836978935596, "OLANZAPINE": 6.136414989644538, "STALEVO": 60.21426549310371, "ZYPREXA": 2.704758957505391, "null": 2.39780110431732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3880.json
index 192c0914b1f..be9ee14a739 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3880.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3880.json
@@ -1 +1 @@
-{"ANORO": 1.1050208521817402, "APIDRA": 1.3243823454089885, "ARANESP": 2.906334527403862, "ATRIPLA": 7.150697716045842, "AUBAGIO": 1.057194258992915, "BEXTRA": 20.60198940620528, "BONVIVA": 4.057248599655636, "BOSULIF": 1.3904745675461927, "BYDUREON": 1.5975271601572727, "CELECOXIB": 14.259902806493685, "ELIQUIS": 4.269053421002841, "ENBREL": 1.970695870994463, "ESBRIET": 2.4463346411128035, "ESOMEPRAZOLE": 2.195249154858371, "EVENITY": 11.528819794365058, "EVISTA": 24.13053188687281, "EXFORGE": 1.287044534680122, "EXJADE": 3.2707006407485224, "FAMPYRA": 6.35517437997437, "FASLODEX": 2.180316259294209, "FIRDAPSE": 1.631749245481176, "FORSTEO": 5.908190019578335, "GLYCOPYRRONIUM": 4.21348263076589, "HIZENTRA": 1.1723658722192238, "HUMALOG": 3.4040746331742224, "IBRANCE": 4.487625372662655, "INLYTA": 1.3505366746207037, "JANUMET": 1.0755042310859166, "JARDIANCE": 1.942262676253919, "KALETRA": 3.121032832714402, "LANTUS": 2.5774553987268227, "LEVEMIR": 2.323481040538985, "OCALIVA": 4.097836635741317, "OFEV": 3.044727896251443, "OPSUMIT": 2.8809232767830277, "PANTOPRAZOLE": 4.70474611388028, "RAPAMUNE": 4.306724710695486, "REVATIO": 9.35530300055881, "REYATAZ": 4.0953973062765305, "SIMPONI": 1.4606938441803416, "SOLIRIS": 1.1833553790240536, "SPINRAZA": 4.253945306229179, "STALEVO": 3.4761500931010025, "STRIBILD": 5.156764603971011, "SUBOXONE": 1.323390647135856, "TERIPARATIDE": 15.484716274988267, "TOUJEO": 1.89063192112918, "TOVIAZ": 1.7101776518462577, "TRACLEER": 2.583591211890956, "TRELEGY": 8.816957661870658, "TRUVADA": 6.635462243554665, "VELTASSA": 4.809590408597058, "VFEND": 2.136264593125449, "VIAGRA": 1.047843695812947, "VIREAD": 5.453202905620159, "VOTRIENT": 1.685743049565227, "XALKORI": 1.88060008896686, "XELJANZ": 4.684246613409992, "XOFIGO": 2.1735032765630296, "XTANDI": 3.95226414268878, "null": 1.2211860222236337}
\ No newline at end of file
+{"COMIRNATY": 0.3175748672206643, "JETREA": 1303.6266700816795, "KEPPRA": 2.341275909637081, "SILDENAFIL": 23.03630613635852, "SPIKEVAX": 0.1550752236510546, "TOZINAMERAN": 1.0347628275610612, "VAXZEVRIA": 0.2938873686378794, "VFEND": 73.01145294112155, "VIAGRA": 19.35378657567842, "VORICONAZOLE": 31.31668213202654, "null": 0.8237444947648335}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3881.json
index 060c79a055e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3881.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3881.json
@@ -1 +1 @@
-{"ATRIPLA": 2.4156702687435168, "BENLYSTA": 3.567568354149594, "CIMZIA": 3.1395880281686988, "COMBIVIR": 29.4247876783338, "ELIQUIS": 1.5190227801085563, "ENBREL": 2.418730405285088, "EXJADE": 2.9352915188951987, "FORSTEO": 4.1271030528084, "IBRANCE": 3.2873396020775782, "IRON": 28.855271783546023, "JARDIANCE": 1.816284697266964, "KALETRA": 4.531528109753318, "LANTUS": 2.464907337760337, "NAGLAZYME": 18.805963814719306, "OPSUMIT": 3.2827659714076862, "SAXENDA": 5.885408695448563, "SIMPONI": 11.080690849612647, "STELARA": 2.9971319148639286, "STRIBILD": 3.8955786074570313, "TRACLEER": 4.4099615264416165, "TRELEGY": 7.263830844368628, "TREMFYA": 11.315971226143631, "VOTRIENT": 7.112025275118933, "XELJANZ": 5.592309278149666, "null": 1.1228600783803535}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3882.json
index c8c072964fa..8475abd811e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3882.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3882.json
@@ -1 +1 @@
-{"ASPARAGINASE": 167.13486459068065}
\ No newline at end of file
+{"ABACAVIR": 17.0516850194585, "null": 2.615865497461248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3883.json
index 63a90853f0f..2d6e8888fe3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3883.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3883.json
@@ -1 +1 @@
-{"CICLOSPORIN": 32.54001191164458, "GARDASIL": 2.257764834363822, "OLANZAPINE": 8.276375450815959, "null": 2.208457376984849}
\ No newline at end of file
+{"COMIRNATY": 1.926759444018208, "FORSTEO": 4.168522765881235, "SPIKEVAX": 0.7469851416129256, "SUTENT": 5.161163082067929, "VAXZEVRIA": 0.9290998811645016, "null": 1.1643756789515454}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3884.json
index ee4b4304f7c..9f0867324f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3884.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3884.json
@@ -1 +1 @@
-{"COMIRNATY": 2.5861358106910566}
\ No newline at end of file
+{"ADALIMUMAB": 0.4177874246179778, "AFINITOR": 1.2770322443646656, "AIMOVIG": 1.6025521252961257, "ALEMTUZUMAB": 0.3139480147578491, "ALIMTA": 0.6328376883237692, "ANORO": 0.5086221265011138, "APROVEL": 1.8547168214092933, "ARAVA": 0.0493183118726774, "AUBAGIO": 0.2398063670999108, "AVAMYS": 0.6431546607643212, "AVASTIN": 0.7274594260596007, "BENLYSTA": 0.233668771136408, "BEVACIZUMAB": 0.7326662960315716, "BOCEPREVIR": 6.934465018242256, "BOSULIF": 0.5053532921424413, "BRAFTOVI": 0.3711579176303118, "BRILIQUE": 0.5875525293435994, "BRINTELLIX": 1.447513437060054, "BUDESONIDE": 0.1023865766541763, "BUPIVACAINE": 0.5649488415715754, "BYDUREON": 0.6153884190105815, "BYETTA": 0.3282471968402911, "CABOMETYX": 3.64204476711656, "CAPECITABINE": 1.3076165965343924, "CELLCEPT": 0.317562812202765, "CHAMPIX": 2.2661788981383824, "CIMZIA": 0.0510953317701337, "CLOPIDOGREL": 0.4131804934950039, "COAPROVEL": 1.7651789488180814, "COMIRNATY": 1.3056949138738627, "COSENTYX": 0.1746263031619176, "COTELLIC": 1.376925445363407, "CRIXIVAN": 0.8248841784444131, "CYMBALTA": 0.2953216521357364, "DEXAMETHASONE": 0.3243839299357148, "DOCETAXEL": 0.9377302538315506, "DUAKLIR": 33.53294712539142, "ELIQUIS": 0.3151662129845523, "EMPAGLIFLOZIN": 0.8276652713919922, "ENTRESTO": 0.3322310708296252, "ENTYVIO": 0.1773269783442428, "ERLEADA": 0.9751665599842884, "ESBRIET": 1.2641536253928378, "ESOMEPRAZOLE": 0.5370889040431259, "EUCREAS": 1.104119113268106, "EXFORGE": 0.7300226551359775, "FASLODEX": 1.4677339317872131, "FENTANYL": 0.1102290620159905, "FORSTEO": 0.889557977725103, "FORXIGA": 1.303845902489264, "FULVESTRANT": 0.7215278430534405, "GALVUS": 0.8537003060117241, "GARDASIL": 0.2528725345917741, "HERCEPTIN": 1.423988956891861, "HUMALOG": 0.095114617756651, "HUMIRA": 0.4327822719439741, "HYDROCORTISONE": 0.3621822490513652, "IBRANCE": 1.2825685124457429, "IBUPROFEN": 0.3884336347369327, "INCIVO": 1.7541562329244291, "INCRUSE": 1.194590142298889, "INLYTA": 1.431118092717731, "INVIRASE": 2.7742211693576886, "IRBESARTAN": 2.042372789268117, "IRINOTECAN": 1.2396497098847767, "JANUMET": 0.6778411450584709, "JANUVIA": 0.351049300628959, "JARDIANCE": 1.1353410200541372, "JEVTANA": 1.7048426118793605, "JORVEZA": 14.826606885304164, "KALETRA": 0.5965479960202245, "KEPPRA": 0.3015480295239739, "KEYTRUDA": 0.3791041553231106, "KISQALI": 1.3412967368512352, "LANTUS": 0.3589672872120774, "LENVIMA": 0.8913984119362837, "LEVEMIR": 0.2249359625010729, "LEVETIRACETAM": 0.1598851846323951, "LEVOFLOXACIN": 0.4739791021638958, "LIXIANA": 0.4503638667935391, "LONSURF": 0.7064615582689848, "LYNPARZA": 1.773020101148572, "LYRICA": 0.2090645235684518, "MEKINIST": 0.6271580461660474, "METHOTREXATE": 0.1908120236726234, "MICARDIS": 1.1880959930061368, "MODERNA": 0.9103014798069348, "MULTAQ": 0.5129625409302409, "NEXAVAR": 0.5020560432033611, "NOT": 0.4927301783843413, "NOVORAPID": 0.2468776504170876, "NUCALA": 0.3021231397361385, "OCRELIZUMAB": 1.6293374787530837, "OFEV": 0.9037985412957316, "OPSUMIT": 0.1390812372517411, "PACLITAXEL": 0.6709694117999132, "PANTOPRAZOLE": 1.0912631280481178, "PAXLOVID": 17.681183237595107, "PAZOPANIB": 1.073578734012128, "PEGASYS": 2.6576526095404804, "PEGINTERFERON": 1.881000379701021, "PEGINTRON": 4.881739417072375, "PEMBROLIZUMAB": 0.3142117523946136, "PLAVIX": 0.4843769041735037, "QUTENZA": 1.400358455524194, "REBETOL": 1.0257755022804746, "RELVAR": 1.2127737798869218, "RITUXIMAB": 0.1706633377976555, "ROACTEMRA": 0.1876303393142356, "RUBRACA": 8.58117751879402, "RYBELSUS": 3.8382216287347575, "SAXENDA": 1.2721658484320453, "SHINGRIX": 0.1942035434692425, "SIMPONI": 0.1956214700010705, "SPIKEVAX": 0.7196994008307772, "SPRYCEL": 0.2490224348297228, "STELARA": 0.6676080919531165, "SUBOXONE": 0.3755450906149272, "SUTENT": 3.346460672559044, "SYCREST": 10.523392391982188, "TAGRISSO": 1.6529897116311794, "TAMIFLU": 0.6220218112184043, "TOVIAZ": 0.4318684677533201, "TOZINAMERAN": 1.5136479616624603, "TRELEGY": 1.217848548967496, "TRULICITY": 0.8810162861592076, "VAXZEVRIA": 1.19249348096919, "VIAGRA": 0.3318525642424055, "VICTOZA": 0.5007387864995146, "VOTRIENT": 2.4895757228936373, "XALKORI": 3.847660958208119, "XELJANZ": 0.2743988970059911, "XOLAIR": 0.1244994678320845, "XTANDI": 1.168772824549072, "ZELBORAF": 2.6864448286956706, "ZOSTAVAX": 0.2327970473947763, "ZYPREXA": 0.0838241378761734, "null": 1.3959149786242435}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3885.json
index 8a215b748a9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3885.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3885.json
@@ -1 +1 @@
-{"COMIRNATY": 4.241330605731263, "SPIKEVAX": 1.45176956256939, "VAXZEVRIA": 1.1459980346305505}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3886.json
index 941813cbae8..99c925e4458 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3886.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3886.json
@@ -1 +1 @@
-{"SUFENTANIL": 233.4923689841373}
\ No newline at end of file
+{"AUBAGIO": 2.520265838200848, "CAELYX": 6.83519294491055, "COMIRNATY": 0.2984493240290707, "CYMBALTA": 0.845043493501782, "ELIQUIS": 0.4949851435545937, "FAMPYRA": 4.57018111326474, "GARDASIL": 1.4257441427741488, "IBRANCE": 1.6762571329442169, "KEPPRA": 2.641456722033596, "KYMRIAH": 11.160270710439791, "LANTUS": 2.399949797404464, "PLAVIX": 2.4320191371020456, "SPIKEVAX": 0.1665117958474413, "SUTENT": 0.4195694477196177, "TOVIAZ": 6.4057347398106215, "TOZINAMERAN": 0.3652439497255796, "VAXZEVRIA": 0.1267949490902274, "XELJANZ": 3.483087668111357, "YESCARTA": 49.00119438871456, "ZYPREXA": 1.8091456504062484, "null": 2.586851198040493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3887.json
index c04f2f63afc..c7e9cf91506 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3887.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3887.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3608168611637097}
\ No newline at end of file
+{"COMIRNATY": 1.0960934956966562, "COSENTYX": 8.780519613064982, "HUMAN": 27.5628483320006, "PRIVIGEN": 26.650163352733674, "SPIKEVAX": 0.7901503948508457, "TOZINAMERAN": 1.2836270653672786, "VAXZEVRIA": 0.6315374000241121, "null": 0.6966987905542296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3888.json
index 1814041c38a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3888.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3888.json
@@ -1 +1 @@
-{"ARAVA": 11.067650723711097, "null": 1.7958672730630731}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3889.json
index 603d2265934..f8d74f027c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3889.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3889.json
@@ -1 +1 @@
-{"null": 2.065602363262541}
\ No newline at end of file
+{"ABILIFY": 15.683936610897296, "AERIUS": 1.3943001724788768, "AIMOVIG": 0.218120488191155, "APIXABAN": 0.3888666441181725, "ARAVA": 0.0319621367679693, "ARIPIPRAZOLE": 5.892264476059634, "AUBAGIO": 0.5539540946586323, "AZILECT": 37.07866629272099, "BENZODIAZEPINES": 29.36753253356509, "BOTULINUM": 1.97583342655688, "BRINTELLIX": 1.5655875768974452, "BRIVIACT": 1.7298805049673989, "BUDESONIDE": 0.1541538928653579, "BUPIVACAINE": 1.2955197451675906, "BUPRENORPHINE": 0.5104413101257392, "CANNABIDIOL": 2.270507392317191, "CARBIDOPA": 23.30226691773088, "CELECOXIB": 0.9688138872166576, "CELLCEPT": 0.4128575724504296, "CHAMPIX": 0.6912287746074322, "CICLOSPORIN": 0.1665544455000429, "CLOPIDOGREL": 0.2408223643589464, "COMIRNATY": 0.2316529452851539, "COMTAN": 37.02323090008107, "COMTESS": 29.66992297410299, "CYMBALTA": 2.348108055285279, "CYTARABINE": 0.5500575901116598, "DEXAMETHASONE": 0.5740237368149019, "DEXMEDETOMIDINE": 10.141396308326074, "DULOXETINE": 2.6876799440181958, "ELIQUIS": 0.0874954928206953, "ENTACAPONE": 63.78020925244957, "ENTRESTO": 0.2624855113912202, "FAMPYRA": 0.5757093976106634, "FENTANYL": 2.1609963945236093, "FORSTEO": 0.5072113576061625, "FORXIGA": 0.3524287617716084, "FYCOMPA": 3.749273033091782, "GARDASIL": 5.982727196062557, "HUMALOG": 0.2709623131825896, "IBUPROFEN": 0.3961200473337404, "INBRIJA": 22.129918832832896, "INFANRIX": 3.4374250120919583, "INVEGA": 17.41556131767222, "IRESSA": 0.5695850354831026, "KEPPRA": 2.7992603737321464, "KEYTRUDA": 0.1455169920059448, "KYMRIAH": 0.5830661231508977, "LACOSAMIDE": 2.1052859502188457, "LANTUS": 0.2991517601724342, "LATUDA": 12.065524896485076, "LEVETIRACETAM": 2.775534225488941, "LEVODOPA": 56.28044208587159, "LEVOFLOXACIN": 0.7722801036741221, "LYRICA": 2.511392797851753, "MENVEO": 3.2774674902731102, "MIDAZOLAM": 3.58663225257214, "MISOPROSTOL": 21.520422080572413, "MMRVAXPRO": 0.4874109928708015, "NAGLAZYME": 1.0595657432567032, "NEUPRO": 16.903616598255795, "NIMENRIX": 1.6982582852332069, "NOT": 0.9397125907920596, "OLANZAPINE": 6.049284024865924, "ONGENTYS": 56.53748089743798, "OPSUMIT": 0.2342741990116536, "OPTIMARK": 0.4479061891126639, "PEGASYS": 0.2651978760001008, "PEGINTRON": 0.5425362690133335, "PLAVIX": 0.2879256522138326, "PREGABALIN": 2.746480236270974, "PREVENAR": 2.686329215387332, "RISPERIDONE": 3.3110846549008937, "SHINGRIX": 0.2566338928108587, "SIFROL": 12.306324604090507, "SPIKEVAX": 0.2396542010550552, "STALEVO": 30.289171692590585, "SUBOXONE": 0.9590867525641276, "SUTENT": 0.1424131129082722, "SYCREST": 9.832642160628982, "TAMIFLU": 1.439277907182066, "TASMAR": 28.03310513943156, "TOZINAMERAN": 0.7183029614935831, "VAXZEVRIA": 0.2115307708394019, "VFEND": 1.1158236231958594, "VIMPAT": 2.377223616214762, "XTANDI": 0.8686357338180971, "XYREM": 1.6531919871015412, "ZYPADHERA": 7.768752914180816, "ZYPREXA": 6.596708984899679, "null": 2.453743831873896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/389.json
index 98e303eefe9..3e272157d46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/389.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/389.json
@@ -1 +1 @@
-{"ASPARAGINASE": 241.2498489251392}
\ No newline at end of file
+{"null": 1.0075421944574614}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3890.json
index 243ab4570b9..b263dbc8659 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3890.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3890.json
@@ -1 +1 @@
-{"null": 2.9024745245448345}
\ No newline at end of file
+{"ABILIFY": 78.71990194005416, "null": 2.460117513063409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3891.json
index 38bf48fe427..bac674c2fa1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3891.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3891.json
@@ -1 +1 @@
-{"ENTYVIO": 21.15975744220787, "SIMPONI": 10.36365976381764}
\ No newline at end of file
+{"null": 1.2435810430680123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3892.json
index b5e7a93737a..938d27118af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3892.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3892.json
@@ -1 +1 @@
-{"MYCOPHENOLATE": 100.02330172977037}
\ No newline at end of file
+{"AVASTIN": 8.402934911015592, "COMIRNATY": 0.8841038288074687, "EYLEA": 12.0390694390926, "NEXAVAR": 2.755021144384417, "OPDIVO": 5.147577799946268, "TASIGNA": 6.117977188348803, "VAXZEVRIA": 0.1425164170763206, "ZYPREXA": 2.4759309683808337, "null": 2.4515843534243897}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3893.json
index 06bb368801a..8be019bcaba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3893.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3893.json
@@ -1 +1 @@
-{"null": 1.872168776398728}
\ No newline at end of file
+{"COMIRNATY": 0.1669295360794193, "null": 3.496740888632152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3894.json
index de961b56b8a..9b5dc676630 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3894.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3894.json
@@ -1 +1 @@
-{"ADCETRIS": 304.809430858085, "ATRIPLA": 1.2017649807472124, "BRENTUXIMAB": 509.8437675637159, "CARMUSTINE": 33.858763843380395, "CELLCEPT": 3.1816551009501386, "CHLORMETHINE": 281.84869809354905, "CICLOSPORIN": 7.614481942442609, "CIMZIA": 1.1478917242815203, "COSENTYX": 1.741469724215455, "CYTARABINE": 8.940471354094425, "DOXORUBICIN": 8.221703260208425, "GARDASIL": 3.678976217053104, "HUMIRA": 4.637521360406151, "KALETRA": 5.964419480244043, "METHOTREXATE": 2.890843176311133, "RITUXIMAB": 15.236068865879425, "SIMPONI": 4.143735488941171, "STELARA": 6.94850986938331, "TREMFYA": 10.788756280911102, "XELJANZ": 1.2358507237441176}
\ No newline at end of file
+{"ABACAVIR": 10.37914977592417, "ABILIFY": 40.75733576697601, "ADALIMUMAB": 0.1536596214332528, "AFINITOR": 2.025508381688176, "AIMOVIG": 0.8708252038613488, "AMINOSALICYLIC": 9.76149781482696, "APIXABAN": 1.0435547953586948, "ARAVA": 1.124493327527727, "ARIPIPRAZOLE": 34.6321358854817, "ATRIPLA": 0.5103673928245471, "AVANDIA": 1.7825679849095, "BIKTARVY": 4.884081244106118, "BYETTA": 3.5159773124968674, "CICLOSPORIN": 1.448764747906451, "CLOPIDOGREL": 1.5311254832515684, "COMBIVIR": 11.310499689645104, "COMIRNATY": 0.054059612656827, "DARUNAVIR": 9.200380150104095, "EFAVIRENZ": 18.37151561113225, "ENBREL": 0.6677502059288518, "ENTRESTO": 3.799857783534837, "EPIVIR": 4.8798026076846375, "FASLODEX": 1.2722236583395117, "FORXIGA": 3.3434540227439045, "HUMIRA": 2.299074080600981, "IBUPROFEN": 1.931592342533434, "IRBESARTAN": 7.435931195961746, "ISENTRESS": 6.091680103939657, "JANUMET": 3.605410113075433, "JANUVIA": 4.769396955951773, "JARDIANCE": 0.556785793513269, "KALETRA": 22.44857404701054, "LANTUS": 0.716278726726059, "LOPINAVIR": 78.29968435779139, "METFORMIN": 36.77333980987071, "METHOTREXATE": 2.434886313402341, "NORVIR": 22.02834438013721, "OLANZAPINE": 4.650966983085322, "OMALIZUMAB": 2.05461209797516, "ROACTEMRA": 1.4112903002907464, "SPIKEVAX": 0.0310938034163088, "STELARA": 0.5198142936298272, "SUTENT": 0.4307506418138069, "SYMTUZA": 89.77957649352986, "TASIGNA": 6.694980007114304, "TESTOSTERONE": 9.386557677931464, "TRIUMEQ": 9.697881093398912, "TRUVADA": 0.7172884960472982, "VAXZEVRIA": 0.0243396741559599, "ZOSTAVAX": 4.854788004999213, "ZYPREXA": 16.1814252035681, "null": 0.6105037314082873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3895.json
index 1a5d1d7e758..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3895.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3895.json
@@ -1 +1 @@
-{"ADCETRIS": 382.1259086586443, "BUSULFAN": 39.907332911292194, "CARMUSTINE": 575.0677120621181, "CHLORMETHINE": 1654.3781031227663, "DOXORUBICIN": 142.66811151216874}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3896.json
index b2e7b6bb632..d72cf823c98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3896.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3896.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"AIMOVIG": 0.2888310244105427, "AUBAGIO": 0.1047515063271998, "CAPECITABINE": 0.2571051506242646, "COMIRNATY": 10.925482617758004, "CYMBALTA": 0.0397677104300578, "ELLAONE": 4.680213937965393, "ESMYA": 1.2950814460685287, "EVRA": 1.0964050162440218, "GARDASIL": 1.586335299434504, "HYDROCORTISONE": 0.3108349300772616, "MAVENCLAD": 1.6289220282164494, "MODERNA": 6.480535167294683, "OCRELIZUMAB": 1.3587667083558586, "SPIKEVAX": 2.4592894067738795, "STELARA": 0.3519657546775684, "TOZINAMERAN": 5.361330102462249, "VAXZEVRIA": 0.6090190743381118, "null": 0.0540787199636722}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3897.json
index eb002e424db..94525190ca2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3897.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3897.json
@@ -1 +1 @@
-{"IBUPROFEN": 76.30012311567708, "null": 2.279796500993944}
\ No newline at end of file
+{"IRBESARTAN": 134.92989091020652, "null": 2.830621118694401}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3898.json
index cea0232de57..8e5e98d6901 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3898.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3898.json
@@ -1 +1 @@
-{"FENTANYL": 63.09294832643059}
\ No newline at end of file
+{"null": 3.5399459944207345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3899.json
index 6dd5c771b09..0f942559e04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3899.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3899.json
@@ -1 +1 @@
-{"ABILIFY": 4.973334938760129, "ARIPIPRAZOLE": 6.961820042766228, "BRINTELLIX": 4.141315549519621, "BUPRENORPHINE": 2.1238575846109318, "CHAMPIX": 21.39171824046908, "CYMBALTA": 6.806799998174776, "FYCOMPA": 58.91360866932415, "KEPPRA": 3.657188906861641, "LATUDA": 14.177840724623346, "PEGASYS": 11.84520654733562, "PEGINTRON": 16.966296080411045, "SUBOXONE": 5.45277601633491, "ZYPREXA": 3.069224600526086, "null": 2.303396878402684}
\ No newline at end of file
+{"COMBIVIR": 8.129044492437178, "KALETRA": 2.923460574139013, "KEPPRA": 4.952210724596361, "LEVETIRACETAM": 6.939375777940857, "METHOTREXATE": 1.6042515650921672, "VIMPAT": 6.3371493952647295, "ZYPREXA": 1.1711271238499188, "null": 11.82966727161232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/39.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/39.json
index 5bc85f114e8..34a104a0de8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/39.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/39.json
@@ -1 +1 @@
-{"COMIRNATY": 2.8367571727452314, "TOZINAMERAN": 1.0867010208900425, "XARELTO": 61.50583073755554}
\ No newline at end of file
+{"null": 2.394081166501609}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/390.json
index 764eb53157c..3ea1e0f77ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/390.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/390.json
@@ -1 +1 @@
-{"ENTYVIO": 16.063526203084294, "NEXAVAR": 4.795745054407323, "SUTENT": 8.107736793229172, "null": 1.89083636762227}
\ No newline at end of file
+{"ABATACEPT": 14.15957057368352, "ACLASTA": 94.10219370372036, "ADALIMUMAB": 9.996310073338542, "APTIVUS": 110.52070008424252, "ARAVA": 2.725643760105183, "AUBAGIO": 6.4278130349641085, "AVAMYS": 30.97634188610285, "CICLOSPORIN": 2.159388666746173, "HUMIRA": 3.995588615920731, "JAKAVI": 4.095332633510832, "KEYTRUDA": 2.048460936959471, "LEVOFLOXACIN": 2.206805703406878, "NEXAVAR": 4.338331987285797, "PEGASYS": 3.366536908045192, "QARZIBA": 137.8004464089082, "YESCARTA": 29.440642694940514, "null": 0.4069946515568483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3900.json
index 348e1f51b76..90136ef96b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3900.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3900.json
@@ -1 +1 @@
-{"CYMBALTA": 2.2442356831622914, "OLANZAPINE": 5.19260360471046, "PEGASYS": 2.7195326283713595, "PEGINTRON": 10.86144446340948, "SUBOXONE": 14.88869583374211, "null": 4.9188043205911285}
\ No newline at end of file
+{"COMIRNATY": 0.93915243068606, "GARDASIL": 10.603316960373816, "null": 1.968209442885492}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3901.json
index 3ef18fc78fb..522fbf05e76 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3901.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3901.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0862438702986148, "COSENTYX": 2.834271164812374, "IBRANCE": 1.9102623313268656, "KAFTRIO": 63.25695761486933, "PEGASYS": 1.800844623108769, "RINVOQ": 11.39450420949474, "RITUXIMAB": 6.244216407819965, "SHINGRIX": 3.615883212957467, "TOZINAMERAN": 1.2306499114693854, "XELJANZ": 3.00115072256945, "ZOSTAVAX": 2.509776644258744}
\ No newline at end of file
+{"ABACAVIR": 0.4003080812975026, "ABASAGLAR": 0.744067069162297, "ABATACEPT": 0.8377623740365284, "ABILIFY": 0.156913259104879, "ACLIDINIUM": 5.982304367531809, "ACTOS": 0.6841585083445408, "ADALIMUMAB": 5.6284455796841, "ADEMPAS": 3.860989987772288, "ADENURIC": 1.0918304959455505, "AERIUS": 1.301364203310958, "AFINITOR": 0.4254799080701303, "AIMOVIG": 4.382542914875407, "ALEMTUZUMAB": 0.4560169697056745, "ALIMTA": 0.2999474278325287, "AMINOSALICYLIC": 5.575246308052946, "ANAKINRA": 0.7455320061515067, "APIDRA": 0.5964023237768303, "APREMILAST": 3.7391949386541614, "APREPITANT": 2.4009209694429616, "APROVEL": 2.1767888702875564, "ARAVA": 1.6172615873559513, "ARIPIPRAZOLE": 1.878781521041149, "ATRIPLA": 0.030158067784016, "AUBAGIO": 0.592962759033516, "AVAMYS": 6.4932332643644015, "AVANDIA": 0.1446769444169958, "AVASTIN": 0.6064462202592595, "AZATHIOPRINE": 0.1838849797382643, "BARACLUDE": 0.8763245856012225, "BEDAQUILINE": 1.6114342975972276, "BENLYSTA": 0.3875864836298779, "BETMIGA": 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2.020503727977837, "VAXZEVRIA": 0.4189929815238866, "VIAGRA": 1.2261914942050447, "VICTOZA": 3.2385505533081664, "VIRAMUNE": 1.611208488649118, "VOTRIENT": 1.0978945745836632, "XALKORI": 2.206614579092871, "XARELTO": 0.6781390484644313, "XELJANZ": 1.5675140017175084, "XOLAIR": 0.4626343649943782, "XTANDI": 0.850817805695285, "ZEJULA": 2.3227307643694206, "ZEPATIER": 2.0425352548633824, "ZOSTAVAX": 0.9398967827052634, "ZYLLT": 8.012185363188555, "ZYPREXA": 0.3772060269926856, "null": 1.246694807614963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3902.json
index 3ba39d0f281..06c5cc2e3cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3902.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3902.json
@@ -1 +1 @@
-{"AIMOVIG": 1.3290684620329878, "BUPRENORPHINE": 3.020590107473531, "COMIRNATY": 3.5060051168511563, "DOXORUBICIN": 18.69116421200922, "GARDASIL": 2.360556084434402, "OMALIZUMAB": 3.6160473735633847, "PREGABALIN": 3.23126701580303, "SPIKEVAX": 1.130322469354391, "TOZINAMERAN": 1.4950484427297197, "ZOSTAVAX": 1.2128919948262498}
\ No newline at end of file
+{"ABACAVIR": 0.3119930228378418, "ABILIFY": 1.3388215462272817, "ACLIDINIUM": 5.144541199056696, "ADALIMUMAB": 0.0136882873196398, "AERIUS": 1.375479853149433, "AFINITOR": 1.8008661215310553, "AIMOVIG": 0.4390985261351354, "ALEMTUZUMAB": 0.6607708387808227, "ALIMTA": 0.8142994173301806, "ALISKIREN": 17.394934990763517, "APIDRA": 0.5777487817701619, "APROVEL": 0.5010003037846075, "ARANESP": 0.4332494179353146, "ARAVA": 0.3371610075270435, "ARIPIPRAZOLE": 0.5572820869655648, "ATAZANAVIR": 1.9752544214461287, "ATEZOLIZUMAB": 2.381758276940918, "ATRIPLA": 0.0501816219381332, "AUBAGIO": 1.1701940219309612, "AVANDIA": 0.2047170332639987, "AVASTIN": 0.8906427422363085, "AZACITIDINE": 0.4183765394349201, "AZATHIOPRINE": 0.4242399069488882, "AZILECT": 1.7966321869397603, "BARACLUDE": 1.6829390253111554, "BEDAQUILINE": 0.6608367433932292, "BENLYSTA": 0.3328982318698952, "BETAFERON": 0.5790093067484824, "BETMIGA": 0.8583056435902889, "BEVACIZUMAB": 0.7926252972300635, "BIKTARVY": 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"VAXZEVRIA": 0.269114115334593, "VELTASSA": 0.5214404907901138, "VEMLIDY": 8.147846033925518, "VENCLYXTO": 1.6570648362743727, "VENETOCLAX": 2.0152991192318424, "VFEND": 0.4623760687392512, "VIAGRA": 0.5643335225382634, "VICTOZA": 0.3847462648267684, "VIMPAT": 1.7082287812902253, "VOTRIENT": 1.206125688138402, "XALKORI": 2.721957920702261, "XARELTO": 0.6900059690907454, "XELJANZ": 0.5397731322204686, "XELODA": 1.9517341842364369, "XOLAIR": 1.2037428666185273, "XTANDI": 6.667219705365622, "YERVOY": 0.7089820613589431, "YESCARTA": 1.1467389126552865, "ZAVESCA": 9.080036573708147, "ZELBORAF": 3.2535979407698523, "ZEPATIER": 2.359828298224959, "ZOSTAVAX": 0.8075177416981562, "ZYPADHERA": 0.807219816393967, "ZYPREXA": 1.9281442262193773, "null": 1.626269265820829}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3903.json
index cc28a48ccbd..ca7541abac4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3903.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3903.json
@@ -1 +1 @@
-{"FULVESTRANT": 267.2708878944481, "KISQALI": 127.9005657796427, "RIBOCICLIB": 739.6284857264747}
\ No newline at end of file
+{"ABACAVIR": 1.942834603829827, "CHAMPIX": 3.146561454865356, "COMIRNATY": 0.436701304624203, "CYMBALTA": 2.878691317063636, "FENTANYL": 2.8291574110290343, "GARDASIL": 0.973709282325604, "KEPPRA": 5.516796096846513, "LANTUS": 0.6700396107280565, "LATUDA": 5.721153603028377, "LYRICA": 3.002773352252828, "OLANZAPINE": 2.9185896649704755, "SPIKEVAX": 0.3118869846007316, "TOZINAMERAN": 1.24146699662915, "VAXZEVRIA": 0.3054358957046842, "ZYPREXA": 3.370030340456351, "null": 2.225072092753627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3904.json
index 705be2fa920..94a140fc87d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3904.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3904.json
@@ -1 +1 @@
-{"EVEROLIMUS": 257.72149654337187}
\ No newline at end of file
+{"ABACAVIR": 0.1392820097701875, "ABILIFY": 0.6509804123859074, "AERIUS": 0.9441099766534716, "AFINITOR": 1.343222043643949, "AIMOVIG": 0.1636008111447241, "ALIMTA": 0.356323518948113, "ANORO": 2.4291229468287776, "APIXABAN": 0.3735557054693285, "ARAVA": 0.0879178450353673, "ARIPIPRAZOLE": 0.3664670351788519, "AUBAGIO": 0.4373837322534972, "AVAMYS": 0.8818423276231583, "AVASTIN": 1.1873952234018088, "AVELUMAB": 12.464257655064747, "AXITINIB": 13.715147444908686, "AZILECT": 3.058425191190832, "BAVENCIO": 11.912090996202645, "BENLYSTA": 1.55274386985017, "BEVACIZUMAB": 1.2627549048016604, "BOSULIF": 0.7301231623391569, "BOTULINUM": 33.163754844743295, "BRAFTOVI": 0.8926438765000695, "BUDESONIDE": 4.342668859194102, "BUPIVACAINE": 0.7208888757078442, "BYDUREON": 0.7594599215770369, "BYETTA": 0.4783296933999899, "CABOMETYX": 6.048822483666789, "CAPECITABINE": 0.62266148101087, "CELLCEPT": 0.6210091864477577, "CHAMPIX": 0.7633607188517733, "CHOLESTAGEL": 18.24035849344978, "CICLOSPORIN": 0.2079674539423113, "CIMZIA": 0.2274043216138213, "CLOPIDOGREL": 0.520811289522977, "COAPROVEL": 0.6618433434316676, "COMBIVIR": 0.7949468071971393, "COMIRNATY": 0.6243099970207547, "COMTAN": 1.011349251045755, "COSENTYX": 0.9124878036761866, "CYMBALTA": 0.6768334051304016, "DARZALEX": 0.8379315985916286, "DEXAMETHASONE": 0.5207136059470255, "DULOXETINE": 0.4218198941333793, "DUORESP": 15.13635001785534, "ELIQUIS": 0.6836984127244193, "ENBREL": 0.1989474547842295, "ENOXAPARIN": 1.5906806255323247, "ENTACAPONE": 2.1097123571783083, "ENTRESTO": 0.5529206759942128, "ENTYVIO": 0.6965991148652644, "ESBRIET": 0.490390614431977, "EVEROLIMUS": 1.5887622482867172, "EVISTA": 0.5009957049560946, "EXFORGE": 0.6812585579617332, "FAMPYRA": 0.4938195408999054, "FASENRA": 3.4216996708338687, "FASLODEX": 0.9322640645846136, "FENTANYL": 0.4162767198888656, "FIRDAPSE": 1.9228392899448843, "FLUTICASONE": 1.2854829273476651, "FORSTEO": 0.590581320001986, "FORXIGA": 0.2107687052362776, "FOTIVDA": 16.328775921289758, "FULVESTRANT": 0.8873419947202831, "GARDASIL": 0.3957145186697678, "HALAVEN": 0.8100874934730768, "HIZENTRA": 0.4418594590109944, "HUMALOG": 0.6448761018942825, "HUMAN": 0.4639777048917195, "IBRANCE": 1.1627670396413543, "IBUPROFEN": 0.2441635555828545, "INCRUSE": 5.983139677246797, "INLYTA": 16.57617538578399, "INSULIN": 0.4920240768764484, "IRBESARTAN": 1.5966819264728245, "IRINOTECAN": 0.524853869970658, "JANUVIA": 0.4447052313661453, "JARDIANCE": 0.4079859457729793, "KEPPRA": 0.1707898946312424, "KEYTRUDA": 4.05114417636358, "LAMIRA": 19.474822639182825, "LANTUS": 0.3938670798044686, "LEMTRADA": 0.8713633641365123, "LENVIMA": 7.856109076067763, "LEVETIRACETAM": 0.3629329393190177, "LEVOFLOXACIN": 1.1936283522820264, "LONSURF": 2.201331234690422, "LYRICA": 0.7682330813418993, "MEPOLIZUMAB": 2.2703431618936434, "METHOTREXATE": 0.6865917630400638, "MICARDIS": 0.7722754389990292, "MMRVAXPRO": 0.4033150582734442, "MODERNA": 0.2648868717914369, "MULTAQ": 0.5167278592983989, "NAGLAZYME": 0.7174846997664556, "NEULASTA": 0.4317769652002251, "NEXAVAR": 6.287836771291168, "NUCALA": 2.07710235901562, "OFEV": 1.260289343151411, "OLANZAPINE": 0.2084919957009958, "OMALIZUMAB": 2.5906456856796725, "ONCASPAR": 1.1215170830875498, "OPDIVO": 0.2792114629875037, "OPSUMIT": 0.5661032307373537, "PANTOPRAZOLE": 0.4384236740672657, "PEGASYS": 0.4653589187597283, "PEGINTRON": 0.5038993982891539, "PEMBROLIZUMAB": 0.9945117775280532, "PLAVIX": 0.32232798351948, "PRIVIGEN": 0.491244417911728, "QUTENZA": 1.8084654233995592, "RASILEZ": 0.693890339185984, "REGORAFENIB": 5.548416506217792, "RELVAR": 33.776965470290435, "REVATIO": 0.5956851539853404, "REVINTY": 53.26779905974566, "REVLIMID": 0.963317201409265, "RINVOQ": 0.3207139893440497, "RIXATHON": 3.551249212173429, "ROACTEMRA": 0.4512415132765482, "RUCONEST": 1.4992395666993823, "SAXENDA": 0.3466031359821441, "SHINGRIX": 0.4399245621705396, "SILDENAFIL": 0.5513530126134062, "SIMPONI": 0.5878317773232544, "SOLIRIS": 0.2073114784276317, "SPIKEVAX": 0.3799011561113053, "STELARA": 0.5816670271465263, "STIVARGA": 14.28653368540536, "SUTENT": 1.2894146250931058, "TAGRISSO": 0.5825059012390729, "TAMIFLU": 0.4543512007838186, "TASIGNA": 0.7503727340470009, "TELMISARTAN": 1.5246318227808016, "TESTOSTERONE": 1.42334713640818, "TOVIAZ": 2.247012548641629, "TOZINAMERAN": 0.9669817634267228, "TRACLEER": 0.2850831654428601, "TRELEGY": 9.22387747064582, "TRULICITY": 0.3015491727161046, "UMECLIDINIUM": 4.415066821444231, "VAXZEVRIA": 0.3002919749023591, "VIAGRA": 0.4622080701721363, "VICTOZA": 0.48866466210611, "VOTRIENT": 1.952788707910189, "XELJANZ": 1.2625599685223254, "XOLAIR": 2.6851119115028546, "XTANDI": 0.6248879762710357, "ZOSTAVAX": 0.5835746317436279, "ZYPREXA": 0.3424851441924007, "null": 1.6856555976045724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3905.json
index 5cb94898275..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3905.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3905.json
@@ -1 +1 @@
-{"ABIRATERONE": 497.7202871067497, "APALUTAMIDE": 357.33944216139383, "CABAZITAXEL": 845.3219083029279, "DOCETAXEL": 31.42073171900225, "JEVTANA": 42.107361549761535, "NUBEQA": 1055.486014613139, "PLUVICTO": 628.3275672818521, "XOFIGO": 2531.64539760757, "XTANDI": 10.83061766443097}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3906.json
index 2d1187c22e0..1d4bfd6439a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3906.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3906.json
@@ -1 +1 @@
-{"BUPIVACAINE": 42.95057068080644, "FENTANYL": 64.93945018368528, "SUFENTANIL": 157.79323117684072, "null": 1.4154222550187263}
\ No newline at end of file
+{"ARAVA": 2.3794933802617173, "ARIPIPRAZOLE": 0.9014692955089264, "BUDESONIDE": 0.8046175419821052, "CHAMPIX": 1.6913269310803978, "CLOPIDOGREL": 0.6186495281786084, "COMIRNATY": 0.58605958990136, "CYMBALTA": 127.09686259495606, "HUMIRA": 0.8558373782884849, "ISENTRESS": 8.70642763268812, "LEVETIRACETAM": 1.2885716956854538, "LEVODOPA": 9.14877389115202, "LEVOFLOXACIN": 2.072337523565461, "OLANZAPINE": 2.8174497651699064, "PEGASYS": 0.270262214049581, "SPIKEVAX": 0.0696850254474505, "VAXZEVRIA": 0.0662149842883152, "VFEND": 9.36907865211444, "VORICONAZOLE": 3.042502860717484, "ZYPREXA": 0.4959884222131137, "null": 0.7874738617450654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3907.json
index abda0269318..8015a66f072 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3907.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3907.json
@@ -1 +1 @@
-{"ALIMTA": 17.62796954419729, "AUBAGIO": 3.542406764902814, "FIRDAPSE": 31.54554206505523, "KEYTRUDA": 11.291359779707475, "MEKINIST": 10.62283498436832, "OPSUMIT": 16.391617581810436, "TRELEGY": 13.544169009590073, "VELTASSA": 109.95741889958036, "VOTRIENT": 88.34323587239946, "XTANDI": 9.104758627401148}
\ No newline at end of file
+{"GARDASIL": 7.573681381639845, "STELARA": 5.3482566024206015, "null": 0.8308705007615035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3908.json
index 834a3a931e6..59ac4a52573 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3908.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3908.json
@@ -1 +1 @@
-{"ADCIRCA": 6.2916768251943065, "ADEMPAS": 4.697665291767141, "AMBRISENTAN": 2.973524653144432, "AMINOSALICYLIC": 1.0550456441767824, "ANORO": 2.3193984297174604, "APIDRA": 2.695624824094257, "APIXABAN": 5.455143186157754, "ARANESP": 19.47206006717056, "ARIPIPRAZOLE": 2.444667646483264, "ARIXTRA": 1.9319975021695237, "ATAZANAVIR": 1.0582305889080568, "AUBAGIO": 4.616746061367772, "AVAMYS": 3.248076332303526, "BARACLUDE": 3.7727952993017633, "BENLYSTA": 5.406711289728703, "BRIVIACT": 1.364294011590692, "BUMETANIDE": 2.973341954330259, "BUPIVACAINE": 2.5894959370326998, "BUPRENORPHINE": 2.113605751746064, "BYETTA": 1.2472540796071474, "CAPRELSA": 7.2893515022466335, "CIMZIA": 2.871525901494822, "CINRYZE": 9.845387999048516, "CYMBALTA": 1.27229473752009, "DESCOVY": 1.5948474720230783, "DUPIXENT": 5.066538717516255, "ELIQUIS": 4.297572012549787, "ENTYVIO": 1.0506401836052084, "ERLEADA": 2.01637817523183, "EVENITY": 1.1986281136719066, "FIRDAPSE": 2.305664361436756, "FORSTEO": 1.1748167549102888, "FOTIVDA": 4.123921254698673, "GALAFOLD": 3.4804074557423306, "GLYCOPYRRONIUM": 4.657433800374021, "GONALF": 4.756287587870593, "HIZENTRA": 3.655486723706253, "HUMALOG": 1.2663173203097262, "HUMIRA": 1.5330195378181364, "HYCAMTIN": 1.7363050894484235, "ICLUSIG": 1.386862432924727, "INCRUSE": 9.29241578335014, "INSULIN": 1.3075252398483976, "KAFTRIO": 7.685288111599751, "KALYDECO": 37.40684361066212, "KEPPRA": 1.960816835910496, "LAMIRA": 13.920478688864495, "LANTUS": 6.643300619071954, "LEVEMIR": 3.679227575066503, "LONSURF": 7.42618719347173, "MACITENTAN": 4.638759975209124, "MEKINIST": 2.455472691875326, "MEPOLIZUMAB": 4.224066325036662, "MIMPARA": 3.356559704483112, "MULTAQ": 1.003720535208176, "NEULASTA": 27.17484805106171, "NINLARO": 3.901504449895852, "NORVIR": 1.4149192298338964, "NOXAFIL": 1.638487577120708, "NPLATE": 10.694966266236486, "NUCALA": 4.702095792755077, "OCALIVA": 4.310960522177585, "OLYSIO": 1.2420218473578295, "OPSUMIT": 13.169944659777116, "ORKAMBI": 40.20109797178514, "PRIVIGEN": 1.5035772195988304, "RELVAR": 2.9856774168532887, "RINVOQ": 1.965516302060669, "RUCONEST": 1.5376011625016068, "SILDENAFIL": 1.136968186337369, "SIMPONI": 3.212112323620605, "SKYRIZI": 1.9223851002700556, "SOLIRIS": 7.735863960498301, "SPRYCEL": 12.146825424779822, "STELARA": 1.7735175312578308, "SUBOXONE": 5.327027265971126, "SYCREST": 3.449759212018085, "SYNAGIS": 14.812632306586348, "TAFINLAR": 3.607536407949742, "TELMISARTAN": 1.4593595690721382, "TERIPARATIDE": 2.0386633959000635, "TIVICAY": 3.4045985499987865, "TOUJEO": 3.132614835169901, "TRACLEER": 3.345196572229051, "TRELEGY": 13.747641254992166, "TRESIBA": 1.0498557415483434, "TRIUMEQ": 3.81080986709355, "VELTASSA": 62.73956667455344, "VENCLYXTO": 3.730798558980714, "VENETOCLAX": 1.996072063999716, "VICTOZA": 1.4343004734323055, "VIMPAT": 3.5551924961600005, "VOTRIENT": 9.68227827480804, "XARELTO": 1.109205215821847, "XOFIGO": 2.316762870105822, "XTANDI": 7.95369580394521, "YERVOY": 2.899782529060089, "ZYPREXA": 2.049682089854247, "null": 1.225836575683401}
\ No newline at end of file
+{"null": 0.6109129808400738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3909.json
index 40e60a77e1b..71127eb3514 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3909.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3909.json
@@ -1 +1 @@
-{"AIMOVIG": 32.03911444907603, "CHAMPIX": 9.939555826403968, "CYMBALTA": 5.5738376946590815, "FYCOMPA": 23.94001159076202, "KEPPRA": 14.146770505240656, "LATUDA": 10.946057070999917, "LEVETIRACETAM": 7.656645987949806, "LURASIDONE": 134.50611419118653, "OLANZAPINE": 7.582985114456718, "ZYPREXA": 5.845001153648316, "null": 2.5214045148074486}
\ No newline at end of file
+{"1": 3.5490943061549447, "ABACAVIR": 0.0933993306815995, "ABASAGLAR": 0.4025704790398872, "ABATACEPT": 0.8244807283301995, "ABILIFY": 0.2627223544800142, "ABRAXANE": 0.4057403401290889, "ACCOFIL": 1.246620420750333, "ACE": 0.855376240537358, "ACETAMINOPHEN": 1.7275980015047965, "ACLASTA": 0.912399291743278, "ACLIDINIUM": 2.2146747274678558, "ACTOS": 0.5772788897616676, "ACTRAPID": 0.6630606011120004, "ADALIMUMAB": 0.408466369322194, "ADCIRCA": 1.9392815185840768, "ADEMPAS": 2.4589805759814074, "ADENURIC": 0.5159168623054985, "ADVAGRAF": 0.504753755612971, "ADVATE": 0.2930600273275027, "AERIUS": 1.224355382623541, "AFINITOR": 1.7292380666855462, "AGENERASE": 1.0610179834932687, "AIMOVIG": 0.6953749868450689, "AJOVY": 0.7749933612474617, "AKYNZEO": 1.587957795472795, "ALDARA": 0.2195105280148526, "ALEMTUZUMAB": 0.548791279687099, "ALENDRONATE": 1.8302857346547163, "ALIMTA": 0.6822301089086794, "ALISKIREN": 0.2466082358504567, "ALL": 0.4230481525684364, "ALLI": 0.8515553222400184, 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"ZIDOVUDINE": 1.169764577535217, "ZOMETA": 0.4952290501563163, "ZOSTAVAX": 0.2935496311643064, "ZYLLT": 1.3686534296066253, "ZYPADHERA": 0.300052281705647, "ZYPREXA": 0.3320639998296003, "null": 1.2083366936319238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/391.json
index 2ea608f922f..fca143b5d92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/391.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/391.json
@@ -1 +1 @@
-{"COVID19": 7.125327741332961}
\ No newline at end of file
+{"null": 0.6174411127565518}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3910.json
index e9478bede1f..fb802a99052 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3910.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3910.json
@@ -1 +1 @@
-{"ADCIRCA": 2.624695088920644, "ADEMPAS": 1.138832936327557, "AIMOVIG": 1.2893563814011637, "AMBRISENTAN": 1.9592791477704663, "BRINTELLIX": 2.956215049062436, "CABAZITAXEL": 2.287684729266098, "CAELYX": 1.963930901381559, "CHAMPIX": 1.1185515810636502, "CIRCADIN": 1.6913688813652905, "COMIRNATY": 1.7734218777363149, "COVID19": 2.05211389701345, "CYMBALTA": 1.2371859191314385, "DENOSUMAB": 1.9957039133255363, "DOCETAXEL": 1.0113629820608518, "ELLAONE": 4.228055623300692, "EMEND": 1.011797874464038, "ENZALUTAMIDE": 12.87472113055851, "ERLEADA": 9.656146846893924, "ESBRIET": 1.1977130906969355, "ESMYA": 8.709152827239416, "EUCREAS": 1.6120525118588818, "EVISTA": 6.528925471053257, "FASLODEX": 5.2277386044018685, "FLEBOGAMMA": 1.0011322484706298, "FORSTEO": 2.079970881909908, "FULVESTRANT": 2.466065006994868, "HERCEPTIN": 1.0660579850718963, "IBRANCE": 4.070469567484352, "KISQALI": 1.7441110884365962, "LEUPRORELIN": 15.19712763704767, "NUBEQA": 4.145841274519624, "OCRELIZUMAB": 1.9363180172212489, "OLAPARIB": 1.408994588330917, "ORGOVYX": 32.71852701561732, "PERJETA": 1.6707669760546664, "RIBOCICLIB": 2.758221051930096, "RYEQO": 18.619776393643296, "SILDENAFIL": 1.30199860355959, "SPIKEVAX": 1.243410473648593, "TAXOTERE": 1.8992359985526055, "TEDUGLUTIDE": 6.6337027206923445, "TOZINAMERAN": 1.6887009559751152, "VAXZEVRIA": 1.2108386818324577, "VIAGRA": 1.0772830656666212, "XGEVA": 10.009537814005284, "XTANDI": 9.873220279739709}
\ No newline at end of file
+{"AMINOSALICYLIC": 5.174267971881172, "BEDAQUILINE": 19.973183170338768, "BRILIQUE": 57.43063281680008, "CLOPIDOGREL": 3.446844722101716, "COMIRNATY": 0.9752690702465718, "ELIQUIS": 0.9897431338670396, "ENTRESTO": 6.922070749485373, "JANUMET": 4.181503547542258, "KEYTRUDA": 0.7515100939000208, "OMALIZUMAB": 7.883606400836514, "OPSUMIT": 9.181444118958012, "PANTOPRAZOLE": 7.480649097581092, "SPIKEVAX": 0.6033213403321157, "SPIRONOLACTONE": 14.06076764485153, "SUTENT": 0.5819146571194456, "TICAGRELOR": 16.622340433961543, "TOZINAMERAN": 0.8660563918251261, "VAXZEVRIA": 0.2457971373853432, "XOLAIR": 1.4700482620496818, "null": 0.79160650542212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3911.json
index dfebb46cf40..f724c8f7ee1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3911.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3911.json
@@ -1 +1 @@
-{"null": 1.7611919538451286}
\ No newline at end of file
+{"ABACAVIR": 0.3096065712594503, "ABILIFY": 0.5654065440952112, "ABRAXANE": 3.8190710535249415, "ACLIDINIUM": 11.156041974721877, "ADCIRCA": 7.401277973368491, "ADEMPAS": 12.824523977657682, "AFINITOR": 1.9416821034956795, "AIMOVIG": 0.22454789770137, "ALIMTA": 0.9020221580308864, "AMBRISENTAN": 7.761725619343239, "AMIKACIN": 1.2910307599249866, "AMINOSALICYLIC": 0.688340235475671, "ANORO": 2.233586478772062, "APIXABAN": 6.333437320073743, "APROVEL": 0.8411904291076336, "ARANESP": 0.5994913177079774, "ARAVA": 0.1541526993519981, "ATRIPLA": 0.0289260153116486, "AVAMYS": 14.873554646339391, "AVANDIA": 1.6085710227567134, "AVASTIN": 0.3264113841704062, "AZATHIOPRINE": 0.4489789991207922, "BEDAQUILINE": 1.6656384948957792, "BENLYSTA": 0.8260939008064877, "BENRALIZUMAB": 2.149993865559562, "BEVACIZUMAB": 0.6360337902238209, "BINOCRIT": 5.943574659825215, "BORTEZOMIB": 0.903924792538758, "BOSULIF": 1.518709732853495, "BRILIQUE": 7.618061447573855, "BUDESONIDE": 2.1035006709189874, "BYETTA": 0.2218516644169122, "CABOMETYX": 0.52686456916556, "CELLCEPT": 0.8592155957117791, "CHAMPIX": 0.1177573278772019, "CHOLESTAGEL": 22.79024278950676, "CICLOSPORIN": 0.4275968741649632, "CIMZIA": 0.1535420935398481, "CLOPIDOGREL": 1.2720966480165832, "COMBIVIR": 0.4710315568731816, "COMIRNATY": 1.378447068074616, "COSENTYX": 0.3804419212091169, "CYMBALTA": 0.0818333213361629, "CYTARABINE": 0.9293446752783044, "DAPAGLIFLOZIN": 3.0759632911647574, "DASATINIB": 4.38142812326102, "DELAMANID": 4.268086469977132, "DEXAMETHASONE": 0.5558186874256548, "DOCETAXEL": 0.8846616842562279, "DULOXETINE": 0.5270450129033517, "ELIQUIS": 0.9995322363021826, "EMPAGLIFLOZIN": 1.041691282208756, "ENBREL": 0.2485900207374869, "ENTRESTO": 2.944505933026446, "ENTYVIO": 0.6063687535089898, "ESBRIET": 3.6884725150864113, "ESOMEPRAZOLE": 1.9218724641648923, "EXFORGE": 0.4002467718132229, "EXJADE": 0.8631651578920259, "FASENRA": 1.793063017266041, "FASLODEX": 1.9753688979536248, "FENTANYL": 0.2138441784502126, 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3.331870850676523, "RIBAVIRIN": 1.798490786634838, "RINVOQ": 1.089765354393928, "RIOCIGUAT": 40.80273422367407, "RITUXIMAB": 1.328672541497689, "RIVAROXABAN": 2.841231163759238, "RUBRACA": 1.1402046270564368, "SEEBRI": 14.482065994242468, "SHINGRIX": 0.3586828864670709, "SILDENAFIL": 4.201735777816239, "SIMPONI": 0.3517068848410828, "SOLIRIS": 1.3123381533535978, "SPIKEVAX": 0.92257363092846, "SPIRONOLACTONE": 1.8165606803523453, "SPRYCEL": 2.16250888703444, "STELARA": 0.1518002751883806, "STIVARGA": 0.731527976123346, "SUTENT": 0.6869238694541764, "TAGRISSO": 1.4129764985187014, "TASIGNA": 1.3830677457273182, "TICAGRELOR": 1.6137610653037544, "TORISEL": 1.5909524017553027, "TOZINAMERAN": 0.6611385576247083, "TRACLEER": 4.141406100953541, "TRELEGY": 3.55603363050153, "TREMFYA": 0.5393574196925, "TWINRIX": 0.695034403875825, "UMECLIDINIUM": 9.437011834270232, "VALSARTAN": 1.7680368198317202, "VAXZEVRIA": 0.419677752234546, "VFEND": 0.2971015972849398, "VOTRIENT": 1.023022239160984, "XALKORI": 0.886472335482981, "XARELTO": 1.14899939181857, "XELJANZ": 0.3666789600853669, "XOLAIR": 2.1145989537354444, "XTANDI": 0.3966358939731704, "ZOSTAVAX": 0.7294519358205666, "ZYPREXA": 0.1194551063326266, "null": 0.6930468315127577}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3912.json
index 53735dc097c..467f6123cc4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3912.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3912.json
@@ -1 +1 @@
-{"ADALIMUMAB": 35.954877412028665, "XOLAIR": 156.16425587215184}
\ No newline at end of file
+{"AVANDIA": 8.603117149973123, "BRILIQUE": 31.63490670143746, "COMIRNATY": 0.2465368184093877, "ENTRESTO": 19.07967881430109, "null": 1.199847298647472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3913.json
index 07c1f4fa389..c0148a27734 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3913.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3913.json
@@ -1 +1 @@
-{"ABATACEPT": 31.064447951053896, "ADALIMUMAB": 68.83068999167335, "ANAKINRA": 327.4727936270185}
\ No newline at end of file
+{"AVAMYS": 12.617531034943571, "COMIRNATY": 0.3349275892233582, "VAXZEVRIA": 0.2509978096293541, "null": 4.617664462309555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3914.json
index e3031df22ac..3037b44917b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3914.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3914.json
@@ -1 +1 @@
-{"ASPARAGINASE": 1957.7473921606545, "CYTARABINE": 63.03107189827492}
\ No newline at end of file
+{"COMIRNATY": 0.3702118786176727, "null": 1.9349146706434224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3915.json
index 23bfc9317a6..8859a355ce8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3915.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3915.json
@@ -1 +1 @@
-{"REVLIMID": 86.19494375627822, "null": 5.981185033238219}
\ No newline at end of file
+{"ABILIFY": 1.765743535409545, "ADCIRCA": 2.4250174265014217, "AFINITOR": 0.9291848249643893, "AIMOVIG": 1.0706284361902645, "ARANESP": 0.3766013587781204, "ARAVA": 0.2632118570837228, "ARIPIPRAZOLE": 1.8321128399748896, "ATRIPLA": 3.24382861911607, "AUBAGIO": 2.589664259707972, "AVANDIA": 0.2306042221917659, "AZILECT": 7.984543126913088, "BENLYSTA": 0.7065538618204888, "BIKTARVY": 0.967265410024982, "BRAFTOVI": 0.9221241866640985, "BRINTELLIX": 0.67158275209188, "BUPRENORPHINE": 0.6442588049407657, "BYDUREON": 0.7434821099274289, "CHAMPIX": 0.3824825073190314, "CIMZIA": 0.535107839645115, "CLOPIDOGREL": 0.3070393746634419, "COMIRNATY": 0.642584754732973, "COMTAN": 2.4649163067246787, "COSENTYX": 1.6126887288240597, "CYMBALTA": 0.918435472029592, "DULOXETINE": 3.624555366428411, "ELIQUIS": 0.503093502908081, "ENBREL": 0.9983449399794582, "ENTRESTO": 1.422055879118212, "EXFORGE": 2.0673682986739044, "EXJADE": 0.4216108496431602, "FAMPRIDINE": 7.655010928740602, "FAMPYRA": 7.532376919997846, "FASENRA": 1.218191765552686, "FASLODEX": 2.09966541174101, "FESOTERODINE": 16.54920250090912, "FORSTEO": 3.0920327620316685, "FORXIGA": 0.4591127858561108, "GARDASIL": 2.2108983695469244, "HUMALOG": 1.3394348080470873, "HUMIRA": 0.5043945833211345, "IBRANCE": 1.5241068026241151, "IBUPROFEN": 0.3790483247130548, "INLYTA": 1.0630750873884458, "JAKAVI": 0.655928880057577, "JANUMET": 0.4078363909449068, "JANUVIA": 0.4101820076854968, "JARDIANCE": 0.2835223434556712, "KEPPRA": 1.1469428142365397, "KEYTRUDA": 1.0902206439619342, "KISQALI": 1.3274779638450829, "LANTUS": 0.7578390030079754, "LATUDA": 0.8935148880406623, "LEFLUNOMIDE": 2.710459972720797, "LEMTRADA": 1.110168401020904, "LEVOFLOXACIN": 0.8300184095489881, "LYRICA": 2.320142687081783, "MEPOLIZUMAB": 1.9057724610416689, "METHOTREXATE": 0.514062103218266, "MICARDIS": 1.8899995889673649, "MMRVAXPRO": 0.2668142382225654, "NEULASTA": 0.8407328718825472, "NEXAVAR": 0.4317331176504012, "NOT": 2.231609408564929, "NUCALA": 0.927059874952618, "OLANZAPINE": 0.4543476774208653, "OPTIMARK": 4.65429154715601, "PEGASYS": 0.5757152584420014, "PEGINTRON": 0.2666064971100577, "PLAVIX": 0.3517775658224318, "PLEGRIDY": 1.4471712892344846, "SHINGRIX": 1.9364146649431335, "SIMPONI": 0.273247021526375, "SOLIRIS": 0.5994688119228364, "SPIKEVAX": 0.9137157392425996, "STALEVO": 5.67475735952977, "STIVARGA": 0.7769415839961792, "STRIBILD": 4.082773270989218, "SUBOXONE": 0.3208820083605126, "SUTENT": 1.5116570312538986, "TAMIFLU": 0.7892682332107389, "TOVIAZ": 2.283403476661986, "TOZINAMERAN": 2.0577220277264505, "TRELEGY": 0.6457601174221115, "TRULICITY": 1.1926448150216522, "TRUVADA": 2.373478567535961, "VAXZEVRIA": 0.4602146266722552, "VIAGRA": 0.8248117603642313, "VIMPAT": 1.3845865593444, "VIREAD": 1.7957432769557322, "VOTRIENT": 0.471791529989193, "XELJANZ": 2.131529715321447, "XOLAIR": 0.465023288232971, "XTANDI": 2.023859496255933, "ZOSTAVAX": 0.2449282136863732, "ZYPADHERA": 4.682801435551391, "ZYPREXA": 0.803901806968289, "null": 1.0476509978045907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3916.json
index d269d575f97..bc33647c6b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3916.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3916.json
@@ -1 +1 @@
-{"CICLOSPORIN": 237.12043410869265}
\ No newline at end of file
+{"ABILIFY": 39.15235187709575, "ARIPIPRAZOLE": 20.93188842825996, "BRINTELLIX": 1.1247022184207411, "BRIVARACETAM": 7.855907506312775, "BUPRENORPHINE": 1.2759802801221165, "CARBIDOPA": 14.53640192749762, "CARIPRAZINE": 45.30758212232775, "CHAMPIX": 0.5106076827494609, "COMIRNATY": 0.0674808457793221, "COMTAN": 6.988147821292804, "CYMBALTA": 1.7775485458750286, "DEXAMETHASONE": 1.698295734676388, "DULOXETINE": 4.371275662707695, "ENTACAPONE": 30.165469395079832, "FENTANYL": 1.3905580529814356, "GARDASIL": 0.9981256216964804, "INVEGA": 18.64753383363957, "KEPPRA": 2.148328565333581, "LATUDA": 43.07225106585189, "LEVETIRACETAM": 1.7286428211782985, "LEVODOPA": 14.121036460241662, "MIDAZOLAM": 7.297579889698688, "OLANZAPINE": 16.798223933870705, "PEGASYS": 0.2982938156924813, "PEGINTRON": 0.5835837865299373, "RISPERIDONE": 11.700979329501202, "SIFROL": 5.454671926522068, "SPIKEVAX": 0.0315490313499671, "STALEVO": 10.376329680771184, "SUBOXONE": 0.7263969227218466, "SYCREST": 11.28204736198916, "TAMIFLU": 1.4418498186656343, "TOZINAMERAN": 0.2655336040935031, "VAXZEVRIA": 0.0690233888752926, "ZYPADHERA": 4.480892946158898, "ZYPREXA": 13.317688292937348, "null": 2.676054122796136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3917.json
index ac3b6e1136f..a6119ce918a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3917.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3917.json
@@ -1 +1 @@
-{"CELLCEPT": 34.30181760294619, "CICLOSPORIN": 12.68645977088494, "null": 2.515908217122853}
\ No newline at end of file
+{"ARIPIPRAZOLE": 87.25994636402729}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3918.json
index f97a720552c..a4d72c429f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3918.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3918.json
@@ -1 +1 @@
-{"BUSULFAN": 118.49804674405908, "CELLCEPT": 37.357401334036176}
\ No newline at end of file
+{"ABACAVIR": 0.5596525672852601, "ABILIFY": 0.6283927103120285, "AFINITOR": 0.5508813423496678, "AIMOVIG": 0.8540702632743853, "ALDARA": 4.322488389978663, "ANORO": 2.4431385863607664, "APIDRA": 0.5543418015067929, "ARAVA": 0.0313260604877848, "ARIPIPRAZOLE": 0.4731809070888234, "ASPARAGINASE": 0.518405616897579, "ATRIPLA": 0.3901936200601008, "AUBAGIO": 0.8801559459391674, "AVASTIN": 0.3736240563649595, "AZATHIOPRINE": 0.7081063282123196, "BENLYSTA": 2.4623047555874487, "BETMIGA": 14.081119804603617, "BEVACIZUMAB": 0.953961326194253, "BINOCRIT": 6.802686601984546, "BRINTELLIX": 1.5291022135792895, "BUDESONIDE": 0.4917679075259123, "BUPIVACAINE": 2.758404919748561, "BUPRENORPHINE": 0.5597272170033204, "BUSULFAN": 1.0853023337578855, "BYDUREON": 0.5097725890109999, "BYETTA": 0.9907787728289468, "CELLCEPT": 1.3322659540893091, "CHAMPIX": 0.9959047549569868, "CICLOSPORIN": 1.3435262543127966, "CIMZIA": 0.1990219687729101, "CLOPIDOGREL": 1.8628244232048965, "COMIRNATY": 0.254955704439428, "COSENTYX": 1.5277605989679042, "CRIXIVAN": 2.561658384609569, "CYMBALTA": 1.6838832151896794, "CYTARABINE": 0.8989542811076525, "DENOSUMAB": 6.929501558249445, "DEXAMETHASONE": 0.9059217941547324, "DULOXETINE": 1.0597241725466218, "ELIQUIS": 1.1453501729828617, "EMPAGLIFLOZIN": 4.041370388861208, "ENBREL": 0.1639624642312939, "ENTRESTO": 0.9278372166871756, "ENTYVIO": 0.5969159442509966, "ERLEADA": 1.2835528571456625, "ESOMEPRAZOLE": 1.109827175794509, "EXFORGE": 1.7888007450676349, "EXJADE": 1.3131859245638224, "FAMPYRA": 0.6312688072154177, "FASENRA": 0.9054468925481068, "FASLODEX": 1.4131423367200615, "FENTANYL": 0.5381480042990594, "FORSTEO": 1.1934109282126515, "FORXIGA": 10.48875727603429, "GARDASIL": 2.680385824809301, "HIZENTRA": 1.075473735181507, "HUMALOG": 0.4564502110679813, "HUMIRA": 0.8398349857385041, "HYDROCORTISONE": 2.4891874598136163, "IBRANCE": 0.7199552110751306, "IBUPROFEN": 1.3186238802851922, "ICLUSIG": 1.189068893267568, "INCRUSE": 3.537017732191505, "INLYTA": 0.6759917288442685, "INVEGA": 10.765802833813297, "IRESSA": 1.138343681730963, "JAKAVI": 0.5356033966253685, "JANUMET": 1.378998090732487, "JANUVIA": 0.8660516002679244, "JARDIANCE": 12.019145637311702, "JEVTANA": 1.1687778690334187, "KEPPRA": 0.4500551992385679, "KEYTRUDA": 0.3705451276230722, "LANTUS": 0.7280653886139301, "LATUDA": 1.258364570746061, "LEMTRADA": 0.8252192565807431, "LEVOFLOXACIN": 0.9348120874665368, "LYRICA": 1.7231641169514151, "MEPOLIZUMAB": 0.6380717797073618, "METHOTREXATE": 0.3820875632874596, "MICARDIS": 1.63832684224584, "MIRABEGRON": 12.844730137379438, "MODERNA": 0.4920524083529581, "MULTAQ": 0.8367354261887668, "NEULASTA": 0.624971621552586, "NEXAVAR": 0.2773008211616589, "NOT": 1.919382131887068, "NUCALA": 0.5259925095178437, "OCRELIZUMAB": 0.9004733941637457, "OLANZAPINE": 0.951445095698182, "OLYSIO": 1.3339558790144628, "OMALIZUMAB": 0.8522634630602842, "OPSUMIT": 0.3409506203172631, "OXYBUTYNIN": 4.433828689259756, "PEGASYS": 1.5646643027017724, "PEGINTERFERON": 0.860506355320438, "PEGINTRON": 0.8617217164443601, "PEMBROLIZUMAB": 0.7192272446891357, "PLAVIX": 0.6384510699252838, "PREGABALIN": 0.6435905445231366, "PROLIA": 6.945468874700508, "RANEXA": 2.742075923854959, "RASILEZ": 1.272255262255908, "RELVAR": 1.0622477484844732, "RITUXIMAB": 0.756467208855158, "SAXENDA": 0.8075675458017335, "SHINGRIX": 0.2067039141529173, "SIMPONI": 0.7003747066122558, "SOLIRIS": 0.4830212118612985, "SPIKEVAX": 0.3237019870815351, "SPIRONOLACTONE": 3.1565959007118662, "STELARA": 0.1445207097450696, "STIVARGA": 0.9483082041506578, "STRIBILD": 0.2133051817033902, "SUBOXONE": 1.7967304648087838, "SUTENT": 1.3112825358710372, "TASIGNA": 0.520818588724247, "TIVICAY": 3.0409831746805933, "TOVIAZ": 27.516202212383007, "TOZINAMERAN": 0.4734414283302908, "TRACLEER": 0.3391226790752638, "TRELEGY": 4.933036084646602, "TREMFYA": 0.8855169062150403, "TRUVADA": 0.4488792033144794, "VAXZEVRIA": 0.2218228746894258, "VFEND": 0.3400750042923148, "VIAGRA": 5.3868097707135405, "VICTOZA": 0.5329594876807994, "VOTRIENT": 0.5270815711272046, "XELJANZ": 1.067544295763725, "XOLAIR": 0.2299611388418129, "XTANDI": 1.78394543845614, "ZOSTAVAX": 1.5101909243599625, "ZYPREXA": 1.6191082030749344, "null": 1.591427858185272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3919.json
index b44d98f1464..d205c6f9380 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3919.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3919.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 123.29535663017454, "ASPARAGINASE": 269.4510624146874, "BASILIXIMAB": 52.50389610471233, "BUDESONIDE": 5.109612800459093, "BUSULFAN": 62.01914261454116, "CELLCEPT": 7.231179077667551, "CICLOSPORIN": 15.831105175995434, "CYTARABINE": 37.11896797527905, "EMEND": 56.17913560174131, "MELPHALAN": 85.5061207606328, "MYCOPHENOLATE": 36.96272924040714}
\ No newline at end of file
+{"CLOPIDOGREL": 24.635712952637995, "IVABRADINE": 1124.7900986023074, "null": 1.67230761176729}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/392.json
index 1fae96015fe..35405bfe838 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/392.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/392.json
@@ -1 +1 @@
-{"ABILIFY": 269.13885103715563}
\ No newline at end of file
+{"ABACAVIR": 0.6101917680130899, "ABATACEPT": 0.726128961087833, "ABILIFY": 0.5132608159242592, "ABRAXANE": 1.2675298436494609, "ACTOS": 3.3897976435630683, "ADALIMUMAB": 0.8688056565465518, "ADCIRCA": 0.6855528396792534, "ADEFOVIR": 12.476180096397185, "ADEMPAS": 0.9901723936802994, "AERIUS": 0.6386983400942448, "AFINITOR": 1.1284903722643946, "AGENERASE": 8.297007844238493, "AIMOVIG": 0.0909580445549114, "ALEMTUZUMAB": 0.8687301151938938, "ALIMTA": 2.091530432423037, "ALL": 2.0029074851168747, "ALOXI": 5.256692338989005, "AMIKACIN": 2.8693614475672438, "AMINOSALICYLIC": 1.569746935722354, "ANAKINRA": 0.3597124790956418, "APIDRA": 0.4589879363197938, "APREMILAST": 2.3560331402429986, "APROVEL": 1.0638729620155367, "APTIVUS": 3.219699621697369, "ARAVA": 0.9576103027278586, "ARIPIPRAZOLE": 0.9963555643756452, "ARIXTRA": 1.5023138359771553, "ASPARAGINASE": 2.427576404015586, "ATAZANAVIR": 2.5044205502290144, "ATRIPLA": 0.0570630860589987, "AUBAGIO": 3.9275978861122938, "AVANDIA": 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"IRINOTECAN": 0.9166831668214724, "ISENTRESS": 6.037762618218142, "IVACAFTOR": 15.199951144193657, "JAKAVI": 1.487317650565699, "JANUMET": 0.6630607044406677, "JANUVIA": 0.7706277487404685, "JARDIANCE": 0.3009074085798615, "JEVTANA": 0.5630869055736959, "KAFTRIO": 7.555270667711369, "KALETRA": 2.0761707161602394, "KALYDECO": 3.2811975552251385, "KEPPRA": 0.6061886132278331, "KESIMPTA": 1.27617908252441, "KETEK": 4.355758747178736, "KEYTRUDA": 1.2431682997243203, "KISQALI": 8.697353359952956, "KYMRIAH": 0.6895552804433269, "KYPROLIS": 0.448830707045462, "LAMIVUDINE": 2.064056259812392, "LANTUS": 0.1501505220701915, "LATUDA": 0.3795518991354469, "LEFLUNOMIDE": 1.7741298899562568, "LEMTRADA": 1.652438218761688, "LENVIMA": 1.752841376487864, "LEVEMIR": 0.1615066747471256, "LEVETIRACETAM": 0.6747322439691972, "LEVOFLOXACIN": 2.1704317457342133, "LIXIANA": 0.3617660315437341, "LOPINAVIR": 1.7367617195078051, "LUMYKRAS": 4.91060464575573, "LYNPARZA": 0.3264736592554424, "LYRICA": 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"PALIPERIDONE": 3.1201835625851184, "PANTOPRAZOLE": 1.889374828142648, "PAZOPANIB": 6.005476762618425, "PEGASYS": 2.4862034969428417, "PEGINTERFERON": 2.1932950732357, "PEGINTRON": 1.1147370848152998, "PEMBROLIZUMAB": 1.1845229849091734, "PEMETREXED": 1.0114415950390103, "PIOGLITAZONE": 2.081425096886747, "PLAVIX": 1.0004964244658288, "PLEGRIDY": 1.983587403376401, "PREGABALIN": 0.402665428029032, "PRETOMANID": 19.842860680126417, "PROPRANOLOL": 1.168091935588621, "PROTELOS": 3.333100499717094, "QARZIBA": 2.9143306912352585, "RAPAMUNE": 0.5460161258856089, "RASILEZ": 1.683652486741709, "REBETOL": 1.2320238518990037, "REBIF": 2.547049040670156, "REMDESIVIR": 24.939116223105643, "REVATIO": 0.2148809102610598, "REYATAZ": 2.3407995353814126, "RIBAVIRIN": 1.7085644848985408, "RIBOCICLIB": 8.865599627801314, "RINVOQ": 2.251497959767095, "RISPERIDONE": 2.106335512013991, "RITUXIMAB": 0.6765149882197696, "ROACTEMRA": 2.838202441054841, "ROTATEQ": 0.225896997650706, "RUBRACA": 5.712813801765201, "RUXOLITINIB": 1.8605104881482124, "SAMSCA": 3.272590419130843, "SAXENDA": 0.8303790551163719, "SEMAGLUTIDE": 3.23207518169336, "SILDENAFIL": 0.3883088099877422, "SIMEPREVIR": 2.885063112311953, "SIMPONI": 0.300476588615695, "SIRTURO": 4.805884049268032, "SOLIRIS": 0.3689305443255425, "SOMATROPIN": 1.3285467949124534, "SOTORASIB": 10.805313105473848, "SOVALDI": 1.5978502247028217, "SPIKEVAX": 0.0223015429120114, "SPINRAZA": 0.6270662610203945, "SPIRONOLACTONE": 0.4808119319278409, "SPRYCEL": 0.4380945783865009, "STELARA": 0.3372822589092838, "STIVARGA": 5.307689503512639, "STOCRIN": 3.564923615819831, "STRIBILD": 0.1087302763700062, "SUBOXONE": 0.0916240060900792, "SUTENT": 0.8363717367306996, "TACROLIMUS": 1.5059367486595685, "TAGRISSO": 1.1138290133939983, "TAMIFLU": 1.058405114386693, "TASIGNA": 3.007717441354025, "TAXOTERE": 1.3967314099300077, "TEMODAL": 1.933266242877573, "TEMOZOLOMIDE": 1.3930457228793487, "TENOFOVIR": 4.80622794631563, "TERIFLUNOMIDE": 2.27424550433732, "TESTOSTERONE": 1.0024762632724935, "TIVICAY": 1.5688961368156376, "TOCILIZUMAB": 2.0172808890689065, "TOPOTECAN": 1.5627878068567755, "TORISEL": 1.018442862931472, "TOZINAMERAN": 0.0967578713189854, "TRABECTEDIN": 7.781080583349353, "TRACLEER": 16.617943678441424, "TREMFYA": 1.3860465908716408, "TRISENOX": 4.456980771431938, "TRIUMEQ": 2.221817715406452, "TRODELVY": 0.5132638175592724, "TRULICITY": 0.4478054185731775, "TRUVADA": 0.0926042893748983, "TWINRIX": 1.7077718076761976, "UPADACITINIB": 2.0501458018937315, "VALDOXAN": 4.613056624396, "VAXZEVRIA": 0.0136513982549329, "VEKLURY": 10.550560580499273, "VEMLIDY": 10.911000156161284, "VENCLYXTO": 1.1464058011317584, "VENETOCLAX": 0.7842679858825622, "VFEND": 5.240374653879671, "VIAGRA": 0.3687855000380838, "VICTOZA": 0.5810392218083963, "VIRAMUNE": 4.914150141272623, "VIREAD": 2.1396171183624624, "VORICONAZOLE": 3.2081831815878634, "VOTRIENT": 4.2779773441792575, "XALKORI": 5.693584396010497, "XARELTO": 0.4075748770268759, "XELJANZ": 0.3309881353192221, "XELODA": 0.988757945482157, "XOLAIR": 0.2629896984982378, "XTANDI": 0.2156447476355461, "YERVOY": 0.6710091143525162, "YESCARTA": 0.5743203888091876, "YONDELIS": 6.042228462807276, "ZELBORAF": 1.5032672288108873, "ZEPATIER": 2.894299571840142, "ZIAGEN": 5.377769299481594, "ZINBRYTA": 5.861718054897056, "ZOMETA": 1.424627429356071, "ZOSTAVAX": 0.0760575386195005, "ZYPADHERA": 0.4908273508167851, "ZYPREXA": 4.010272484062591, "null": 1.6056828739509017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3920.json
index 3cab087fa3c..726d096ff0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3920.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3920.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 93.84321926661865, "CICLOSPORIN": 8.064440303491313, "CYTARABINE": 26.09731633108, "null": 1.5393374846995298}
\ No newline at end of file
+{"ERLOTINIB": 907.5501128216642, "GEFITINIB": 3703.5645799823487, "IRESSA": 107.23376182237224, "OSIMERTINIB": 812.9786154550924, "TAGRISSO": 44.62231329418593}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3921.json
index f7e97e0df70..9a9346a215f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3921.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3921.json
@@ -1 +1 @@
-{"CICLOSPORIN": 51.412879327651325, "CYTARABINE": 32.49040592248048}
\ No newline at end of file
+{"null": 1.514987313588726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3922.json
index fe4bdbb4372..5bd4db8ef9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3922.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3922.json
@@ -1 +1 @@
-{"DARUNAVIR": 502.62623383061936, "EFAVIRENZ": 442.46612658309095}
\ No newline at end of file
+{"APIXABAN": 8.955412408615338, "COMIRNATY": 0.8479214255015919, "ELIQUIS": 2.24642578545503, "OMALIZUMAB": 13.275698166024204, "SPIKEVAX": 0.7689476788990643, "TOZINAMERAN": 2.7478362728536005, "VAXZEVRIA": 0.7859109256907759, "null": 0.7076436699238903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3923.json
index 1be55fb5415..e68cf0af852 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3923.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3923.json
@@ -1 +1 @@
-{"BORTEZOMIB": 897.7776851889981}
\ No newline at end of file
+{"ADEMPAS": 3.972356740289452, "AIMOVIG": 0.4739309460293784, "CIMZIA": 0.3001366687635929, "COMIRNATY": 2.664469119700611, "COSENTYX": 1.02310374859117, "CYMBALTA": 0.4004949027533221, "DEXAMETHASONE": 0.5027025014134221, "ELIQUIS": 0.1943445968606695, "EXFORGE": 1.0279145829867138, "FORSTEO": 0.850783795066491, "GARDASIL": 1.698147070761812, "IBRANCE": 0.3854120914193674, "JANUVIA": 0.6841774035316899, "KEYTRUDA": 0.334401200882536, "LANTUS": 0.3288315202615423, "MEPOLIZUMAB": 1.603084375226958, "MICARDIS": 1.3082966603039563, "MMRVAXPRO": 0.497878474920755, "MODERNA": 0.5479814750100426, "NUCALA": 0.6970654107880753, "OMALIZUMAB": 2.828206002965592, "OPSUMIT": 0.5090294524938695, "PEGASYS": 0.5262277495804213, "SHINGRIX": 0.9673048409278936, "SPIKEVAX": 1.6796577797402383, "SUTENT": 0.3070761582906027, "TOZINAMERAN": 3.3371506972454763, "VAXZEVRIA": 1.036537434638895, "VIAGRA": 1.8813600230181915, "XELJANZ": 0.6881633528281893, "XOLAIR": 0.7502384175344226, "XTANDI": 0.5423477891392612, "ZOSTAVAX": 1.3561517558871554, "null": 0.6735652647236375}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3924.json
index c2866cf9ae8..ab9165990bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3924.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3924.json
@@ -1 +1 @@
-{"GARDASIL": 658.4496585751372, "METHOTREXATE": 5.461207995713782, "STELARA": 4.071880291253221}
\ No newline at end of file
+{"COMIRNATY": 0.5634196480835538, "COSENTYX": 4.0560639710679, "CYMBALTA": 0.5898283212936106, "ELIQUIS": 1.6898433874098235, "EXJADE": 1.9306078470431036, "FORSTEO": 1.8388930401302863, "HUMALOG": 1.8463419609663567, "IBRANCE": 1.5603616651476302, "KEPPRA": 1.0189879033896994, "LANTUS": 1.28674731932633, "MEPOLIZUMAB": 5.345516705539579, "NUCALA": 2.4035079270776345, "PEGINTRON": 1.397442304479002, "PLAVIX": 0.9674012477509484, "SPIKEVAX": 0.225661832451566, "SUTENT": 0.5123170505493617, "TOZINAMERAN": 2.245239202413107, "VAXZEVRIA": 0.2421588566625246, "XELJANZ": 2.511131425629038, "ZOSTAVAX": 3.21017356463317, "null": 1.9159440142745945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3925.json
index 334bb31df04..de064e77caa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3925.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3925.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 94.26560487904035, "BORTEZOMIB": 80.96896438242086, "BUSULFAN": 66.82798057863587, "CELLCEPT": 45.997681295795374, "CICLOSPORIN": 55.181797551657}
\ No newline at end of file
+{"BRILIQUE": 14.25038039508051, "CLOPIDOGREL": 2.843066814679871, "COMIRNATY": 0.3533382557927116, "ELIQUIS": 12.69890942850561, "PEGASYS": 1.662631314555025, "PLAVIX": 9.299405690215972, "SPIKEVAX": 0.225919048923937, "TOZINAMERAN": 0.973802427985414, "VAXZEVRIA": 0.4099941301509438, "XARELTO": 12.908940136082927, "null": 1.2594957666104916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3926.json
index c299645c58f..a25cd140bd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3926.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3926.json
@@ -1 +1 @@
-{"APIXABAN": 65.87291187423753}
\ No newline at end of file
+{"ABATACEPT": 4.466869729438858, "ACETYLSALICYLIC": 109.60648405525048, "ADALIMUMAB": 4.5865456916610485, "ARAVA": 1.1563325650999992, "AUBAGIO": 1.296376974178902, "AVAMYS": 1.0762998283554592, "BENLYSTA": 3.191072336130972, "BUDESONIDE": 0.6011312396548454, "CELLCEPT": 0.8503991271898638, "CICLOSPORIN": 0.477081238639104, "CIMZIA": 2.2755026958857165, "COMIRNATY": 0.3774102732103565, "COSENTYX": 2.9943960835692565, "CYMBALTA": 0.4881670576681379, "DEXAMETHASONE": 0.8064244531978331, "ELIQUIS": 0.1636652739797026, "ENBREL": 0.6052610332691492, "ENTRESTO": 0.6221006606204729, "ENTYVIO": 3.067481058346367, "EVISTA": 1.9419760226677163, "EXJADE": 1.4227765670135557, "GARDASIL": 0.4702448471030081, "HIZENTRA": 9.060749119542178, "HUMALOG": 0.2832661158066935, "HUMAN": 3.5370700636436294, "HUMIRA": 0.9863159063807156, "HYDROCORTISONE": 2.579186973061092, "IBRANCE": 1.0649815478793832, "INFANRIX": 4.699601217103091, "KEPPRA": 1.0795924250447189, "LANTUS": 0.2110886246713586, "LEVETIRACETAM": 0.7069575441131691, "MEPOLIZUMAB": 7.174479280279965, "METHOTREXATE": 2.5127388021620307, "MMRVAXPRO": 7.379085670287184, "NAGLAZYME": 16.14292577081708, "NUCALA": 0.6647349953362737, "OMALIZUMAB": 5.442796546679945, "OPSUMIT": 1.4549797653188403, "PEGASYS": 1.766529026547983, "PEGINTRON": 1.0132797757664114, "PRIVIGEN": 1.5367412733168884, "RITUXIMAB": 2.6045850017667767, "ROACTEMRA": 1.750944215824397, "ROTATEQ": 3.7530443921108825, "SILDENAFIL": 2.70790835033851, "SIMPONI": 8.883791233118792, "SOLIRIS": 0.8904793146836125, "SPIKEVAX": 0.2935478248334808, "STELARA": 2.167913867315524, "SUBOXONE": 1.435856447762101, "SUTENT": 0.4577505951501636, "SYNAGIS": 16.310887810141697, "TAMIFLU": 1.0582816136762545, "TOZINAMERAN": 1.0606030876607102, "TRACLEER": 1.1056191377705291, "VAXZEVRIA": 0.3750697673688856, "XELJANZ": 4.161364056710985, "XOLAIR": 3.040112373374012, "XTANDI": 0.4567317996064174, "ZOSTAVAX": 1.1876083822291623, "null": 1.0431345980660192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3927.json
index 4bbfd6e807b..7c8b6594c19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3927.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3927.json
@@ -1 +1 @@
-{"ATRIPLA": 10.63627156988016, "AVANDIA": 2.492301123866433, "ELIQUIS": 1.1636723736029673, "EVENITY": 33.35886865017544, "FENTANYL": 1.7572447387387655, "FORSTEO": 14.91403053005988, "HUMALOG": 2.309384445238891, "IBRANCE": 1.5904859963439797, "KALETRA": 11.830859618891978, "LANTUS": 1.0374368270107126, "OLANZAPINE": 3.332607799779309, "ROACTEMRA": 4.200922381218249, "STRIBILD": 3.2049474000090923, "TRUVADA": 5.683795462987426}
\ No newline at end of file
+{"null": 1.2539596971500002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3928.json
index 9a1ef8d83a2..95f24024ffd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3928.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3928.json
@@ -1 +1 @@
-{"ABILIFY": 86.95783755460094, "OMALIZUMAB": 91.6764137515006}
\ No newline at end of file
+{"COMIRNATY": 3.950705123943216, "SPIKEVAX": 2.6224588293820084, "null": 0.1424921170841658}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3929.json
index b20d0fe4438..d86d41e4571 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3929.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3929.json
@@ -1 +1 @@
-{"RITUXIMAB": 238.6522128619549}
\ No newline at end of file
+{"ADALIMUMAB": 15.368448343880647, "COSENTYX": 27.181806342717657, "null": 0.5022785301358149}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/393.json
index 6121cb58286..1484ba978d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/393.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/393.json
@@ -1 +1 @@
-{"null": 6.628258560056476}
\ No newline at end of file
+{"SPIKEVAX": 35.034519208316254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3930.json
index fd5886c32e2..b3c9bee7b08 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3930.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3930.json
@@ -1 +1 @@
-{"ABILIFY": 2.830918110374303, "APIDRA": 10.082621613127468, "ARAVA": 4.2383840352292, "BRINTELLIX": 11.806560583145044, "BYDUREON": 3.2938966828212943, "BYETTA": 3.876722424592612, "CHAMPIX": 2.0013112574652423, "CYMBALTA": 1.598152714150341, "ENTYVIO": 2.065350345306928, "FORXIGA": 5.251004652904629, "HUMALOG": 5.660684758757535, "IBRANCE": 1.699521683557227, "IMATINIB": 11.328279483676983, "INSULIN": 9.04618132070707, "JANUVIA": 3.573810191574963, "JARDIANCE": 4.790496585940269, "LANTUS": 7.104387778185728, "NOVORAPID": 3.888563228743098, "OLANZAPINE": 2.1589850595903157, "SAXENDA": 37.143218299659054, "TASIGNA": 1.9223804683546837, "TRULICITY": 7.111055611999341, "VICTOZA": 4.773325016414194, "XYREM": 7.412476807352304, "ZYPREXA": 3.0862484602135645}
\ No newline at end of file
+{"ASPARAGINASE": 70.36201745381456, "COMBIVIR": 41.75491384864407, "null": 2.7082584829827576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3931.json
index f23564817c9..d14d8c8d8d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3931.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3931.json
@@ -1 +1 @@
-{"MIMPARA": 1741.8962004735863}
\ No newline at end of file
+{"COSENTYX": 66.06622112394976, "null": 1.1433569970435344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3932.json
index b9d6f65b780..e6f1387e436 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3932.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3932.json
@@ -1 +1 @@
-{"null": 6.067551201987004}
\ No newline at end of file
+{"null": 0.7428750911212086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3933.json
index ba018918af9..e85bf93ef6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3933.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3933.json
@@ -1 +1 @@
-{"PEGINTRON": 229.9380837770497}
\ No newline at end of file
+{"null": 1.43264412131452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3934.json
index e55fddf421d..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3934.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3934.json
@@ -1 +1 @@
-{"SUTENT": 1.846534357823101, "null": 2.357795821263958}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3935.json
index 56e946bb72d..83c073013ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3935.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3935.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 4.752369327297212, "CASPOFUNGIN": 10.15174630840824, "CICLOSPORIN": 4.183203902089193, "CLOPIDOGREL": 3.774310683076077, "COMBIVIR": 11.704667221039369, "DEXAMETHASONE": 5.229250910004191, "ELIQUIS": 2.1295312568348383, "FASLODEX": 2.254379717153779, "HUMALOG": 1.2160913958734176, "KALETRA": 3.872752674717096, "KEPPRA": 1.6610722104434363, "LEVETIRACETAM": 3.035015014493942, "NAGLAZYME": 48.25251103409794, "NOVOSEVEN": 12.765679601474098, "SPINRAZA": 37.80372092143507, "SYNAGIS": 7.379805371220383, "TEMOZOLOMIDE": 16.113104648133792, "VOTRIENT": 1.5919376372842764, "null": 1.7425773836881984}
\ No newline at end of file
+{"ABATACEPT": 5.721388987934711, "ABILIFY": 0.3531216530452502, "ADALIMUMAB": 0.3187533313709189, "AFINITOR": 0.1731645038823172, "AIMOVIG": 0.1987267462446941, "AMINOSALICYLIC": 0.4932458252261977, "ARAVA": 5.567009362341646, "ATEZOLIZUMAB": 4.110325234305359, "AUBAGIO": 0.1873065149632048, "AVAMYS": 0.6012730345105269, "BENLYSTA": 1.105061163440981, "BYDUREON": 0.8679294908293552, "CHAMPIX": 0.3351450206939671, "CHLORHEXIDINE": 3.567740328264242, "CIMZIA": 3.5544377052590046, "CLOPIDOGREL": 0.3113338291975318, "COMIRNATY": 1.7445668257536466, "COSENTYX": 0.9554617395485088, "CYMBALTA": 0.383035375622817, "CYTARABINE": 0.4669645677951874, "DEXAMETHASONE": 0.4237547186163575, "ELIQUIS": 0.0643239478143437, "ENBREL": 0.4281418574619277, "ENTYVIO": 0.4575082088569746, "FASLODEX": 0.2938969429170948, "FORSTEO": 0.6027551885607965, "FORXIGA": 0.3592333876385517, "GARDASIL": 1.6878528919747051, "HIZENTRA": 0.5945446547585564, "HUMIRA": 0.8325583407918113, "HYDROCORTISONE": 1.3956741465521407, "IBRANCE": 0.4251672675217475, "IBUPROFEN": 0.7006335949434467, "KEPPRA": 0.2722944650372922, "LANTUS": 0.0997369566555774, "LEMTRADA": 0.4886328946420261, "LEVOFLOXACIN": 0.1555712523833959, "MEPOLIZUMAB": 0.4939827271451567, "METHOTREXATE": 0.6266138444249918, "MMRVAXPRO": 1.3508914123094806, "MODERNA": 1.3102043170302635, "NAGLAZYME": 6.819212420057196, "NIMENRIX": 1.296481727937022, "NUCALA": 0.572301715315827, "OCRELIZUMAB": 3.648087269378721, "OMALIZUMAB": 1.91989585254292, "OPSUMIT": 0.1684982960647788, "PEGASYS": 0.7008245461930578, "PEGINTRON": 0.9618494848939044, "PLAVIX": 0.1731772517427844, "RELVAR": 1.4839711247073784, "REVATIO": 0.5199918475937113, "RINVOQ": 0.3857164507408834, "RITUXIMAB": 0.6669523515053524, "SHINGRIX": 1.7439505779708502, "SIMPONI": 0.3197027187795895, "SPIKEVAX": 1.4870110456751555, "STELARA": 1.0433007122745692, "SUBOXONE": 0.198196637221554, "SUTENT": 0.2479059992259525, "TAMIFLU": 0.9548899800880688, "TOZINAMERAN": 3.283027618994242, "TWINRIX": 0.6610394174053269, "VAXZEVRIA": 2.5979098126330453, "XELJANZ": 0.7195133406611165, "XOLAIR": 0.7224810406371868, "ZOSTAVAX": 2.3050683203959204, "ZYPREXA": 0.2726295153356359, "null": 0.3297593700667413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3936.json
index 03b778baaf1..91cbf03581b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3936.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3936.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"AVAMYS": 14.30757613848323, "BUDESONIDE": 56.217958225519496, "COMIRNATY": 0.4111360592026614, "COSENTYX": 3.072413069175808, "NUCALA": 77.29541078923836, "RITUXIMAB": 9.56045511525553, "SPIKEVAX": 0.099429846858986, "TOZINAMERAN": 0.6110777292482814, "VAXZEVRIA": 0.0906604749036938, "XOLAIR": 1.3228879342210489, "null": 1.7299976316985195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3937.json
index 6daaea260b2..766840ec46b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3937.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3937.json
@@ -1 +1 @@
-{"ABACAVIR": 1.1997564505452132, "AFINITOR": 2.355897066629236, "ATEZOLIZUMAB": 26.331409446449765, "ATRIPLA": 2.0739293236879965, "AVASTIN": 6.009359386455053, "BEDAQUILINE": 4.571709955477257, "BEVACIZUMAB": 2.4075860870194914, "BYETTA": 2.5738949700547136, "CELLCEPT": 6.18181151048279, "CICLOSPORIN": 4.09998789009813, "COMBIVIR": 10.746430210204553, "CRIXIVAN": 74.3874413742463, "CYTARABINE": 2.346505604908505, "DOXORUBICIN": 5.047385593986239, "ESOMEPRAZOLE": 22.722424141571256, "FASLODEX": 2.7969844117775, "FILGRASTIM": 10.957984356054409, "FORXIGA": 4.744957034518556, "FULVESTRANT": 3.888096545962058, "IBRANCE": 1.3145430019674296, "JANUMET": 2.8036604697081464, "JARDIANCE": 1.536913349832222, "JEVTANA": 14.960358500526286, "KEPPRA": 1.1190646314170525, "KEYTRUDA": 4.033803880570942, "LEVETIRACETAM": 1.386409170816129, "LEVOFLOXACIN": 1.3982088838792035, "LONSURF": 5.704149244143079, "MYCOPHENOLATE": 4.2588562025797145, "NEULASTA": 3.3233207772963778, "NORVIR": 19.56728830786064, "OPDIVO": 1.7129186469322053, "PEMBROLIZUMAB": 3.827272070429225, "REYATAZ": 13.064552364159002, "STELARA": 1.1676869703739028, "STIVARGA": 4.055185546224528, "STRIBILD": 1.6863972307176616, "TOVIAZ": 6.592974148708766, "VOTRIENT": 2.05049387855742, "XOFIGO": 8.682038977987448, "XTANDI": 3.5142821980481207}
\ No newline at end of file
+{"COMIRNATY": 0.9825124720834382, "MMRVAXPRO": 2.030182087393097, "OMALIZUMAB": 5.614240609592539, "SHINGRIX": 1.868572232574522, "SPIKEVAX": 0.844580142044795, "TOZINAMERAN": 2.431996243451363, "VAXZEVRIA": 0.9855082819680444, "XOLAIR": 2.5926258146026218, "null": 1.353775999133106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3938.json
index f2bc649936e..f042764929a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3938.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3938.json
@@ -1 +1 @@
-{"COMBIVIR": 36.51244653979159, "EFAVIRENZ": 112.44335762593488, "null": 2.5623980667993767}
\ No newline at end of file
+{"NAGLAZYME": 224.98271827603617, "null": 1.297734211314603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3939.json
index 3743e314aa9..86a85b8ba4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3939.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3939.json
@@ -1 +1 @@
-{"IRESSA": 39.81332002725986, "MIDAZOLAM": 21.10882132128616, "SUTENT": 7.526787478674223}
\ No newline at end of file
+{"null": 19.98870549377461}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/394.json
index a46a3dc95da..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/394.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/394.json
@@ -1 +1 @@
-{"ACLIDINIUM": 41.7137727036254, "ARANESP": 1162.0121286805934, "DARBEPOETIN": 505.3676511870972}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3940.json
index 1142c6f3aac..0d6da5d0fd7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3940.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3940.json
@@ -1 +1 @@
-{"PRIVIGEN": 899.2415428498616}
\ No newline at end of file
+{"null": 0.6906596195891206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3941.json
index ca0496e52b9..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3941.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3941.json
@@ -1 +1 @@
-{"null": 1.4694116034512523}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3942.json
index d1c2b49d1a8..00d06ded929 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3942.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3942.json
@@ -1 +1 @@
-{"BRINTELLIX": 1.9248807242014847, "COMIRNATY": 2.116839263761337, "COVID19": 1.523301941759844, "GARDASIL": 14.740686373023308, "KEPPRA": 1.0987146946426536, "SPIKEVAX": 1.2664253993010293, "TOZINAMERAN": 2.661869130258236, "VAXZEVRIA": 1.8338554560071696}
\ No newline at end of file
+{"null": 0.9819335484950265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3943.json
index e75c9b88eb3..b5591222040 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3943.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3943.json
@@ -1 +1 @@
-{"ADALIMUMAB": 13.86242020610056}
\ No newline at end of file
+{"BYETTA": 28.94310438815108, "COSENTYX": 9.070353027620046, "JAKAVI": 29.290741236796947, "SAXENDA": 15.180222425405, "SUTENT": 1.9855586111455588, "null": 0.7038338805829444}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3944.json
index f456ed6c732..dc5646cd96a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3944.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3944.json
@@ -1 +1 @@
-{"BEXTRA": 51.88735480816836, "DEXAMETHASONE": 2.3627001535164878, "LEVOFLOXACIN": 7.255328752525575, "MEPOLIZUMAB": 9.012246343986456, "MMRVAXPRO": 2.5340654820322897, "ONCASPAR": 46.069756471356136, "null": 2.9507218982906527}
\ No newline at end of file
+{"BEVACIZUMAB": 32.276525683333055, "CICLOSPORIN": 8.991412706640348, "ENTYVIO": 9.535097593594932, "KEYTRUDA": 56.97268525496919, "NEXAVAR": 12.243618517336646, "PEMBROLIZUMAB": 23.19249218843331, "STIVARGA": 9.22460950437574, "TEMODAL": 65.30374806141688, "TEMOZOLOMIDE": 187.3886423931176, "null": 0.052791565852522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3945.json
index f625ba7c5de..4b3b0d673f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3945.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3945.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 1.529822548754484, "BOSULIF": 3.0743117283482606, "BUPIVACAINE": 7.909444522390193, "BUPRENORPHINE": 1.6722817408093014, "CAPECITABINE": 1.4461634840382855, "COMIRNATY": 2.0332315962782808, "DEXAMETHASONE": 1.3296112209768538, "DULOXETINE": 2.758122219256395, "ENBREL": 1.2802157186814638, "FENTANYL": 7.850210768641397, "GARDASIL": 2.4441828976645663, "INLYTA": 1.6118825743348677, "LENVIMA": 6.203625348806715, "METHOTREXATE": 1.0724250131259374, "QUTENZA": 7.613765454166288, "SHINGRIX": 10.07633204483132, "SPIKEVAX": 1.4881000876188932, "STIVARGA": 1.270242682727134, "SUTENT": 2.661547640044298, "TOZINAMERAN": 1.0595921297156248, "VAXZEVRIA": 2.5837965819208826}
\ No newline at end of file
+{"ABILIFY": 3.207800594176771, "ACETYLSALICYLIC": 72.70826667000149, "AFINITOR": 3.711686803078365, "AIMOVIG": 0.7734652996124345, "ALISKIREN": 92.73527678299102, "ARAVA": 0.4155830958718299, "ARIPIPRAZOLE": 1.4735637257414804, "ATRIPLA": 1.0195239159124092, "BENLYSTA": 1.1124527748959188, "BLINCYTO": 15.19177570764113, "BOSULIF": 2.7939572289236008, "BRAFTOVI": 1.6860604108174428, "BRINTELLIX": 0.7302506967039626, "BUMETANIDE": 11.562453375194776, "BUPRENORPHINE": 1.3279453188691364, "BYETTA": 0.9388279019402594, "CABOMETYX": 0.9447216257042066, "CAPECITABINE": 1.2162970904694916, "CARIPRAZINE": 28.250140462176905, "CHAMPIX": 1.5586263907829012, "CICLOSPORIN": 0.2604523448422954, "COMIRNATY": 0.1845685207907585, "COMTAN": 4.329843932287485, "COSENTYX": 0.7082542085720107, "CYMBALTA": 0.9447223461456912, "CYTARABINE": 0.933825885733409, "DELAMANID": 6.702979451741325, "DEXAMETHASONE": 1.106516513424164, "ELIQUIS": 0.8118619391997609, "ENTACAPONE": 7.421471110924092, "ENTRESTO": 0.6697245057849677, "ESBRIET": 1.8843382874602848, "EXFORGE": 0.9002126818636049, "EXJADE": 0.6741150925268308, "FASLODEX": 1.1057941297618348, "FENTANYL": 1.3648370034783175, "FORSTEO": 1.6913135933402046, "FORXIGA": 0.7502766629058144, "FULVESTRANT": 1.7986561333454831, "GARDASIL": 0.9395395845364314, "HUMALOG": 1.30613909694762, "IBRANCE": 4.065388748878825, "IBUPROFEN": 0.8434797701901235, "INLYTA": 3.904834383043246, "JAKAVI": 1.3262614808436763, "JANUVIA": 0.6558414239556913, "JARDIANCE": 0.875299693654558, "KAFTRIO": 1.770312381910708, "KEPPRA": 1.154786752616913, "KEYTRUDA": 1.516273366674149, "KISQALI": 2.374733127119992, "LANTUS": 0.6378975894336654, "LATUDA": 1.5695041241861836, "LEVODOPA": 5.543899076624224, "LEVOFLOXACIN": 0.5101585830744616, "LUTATHERA": 6.5331749117395095, "LUTETIUM": 24.130595487623506, "LYRICA": 1.8431327474788533, "MEKINIST": 1.2038381701034593, "MENVEO": 6.579215815227368, "MICARDIS": 1.7018412907301217, "NEXAVAR": 2.285514767836658, "NUCALA": 1.02185279548994, "OLANZAPINE": 1.3116154326205214, "OMALIZUMAB": 0.8166822482432515, "OPDIVO": 0.7083505972594699, "OPSUMIT": 1.003441465992202, "PEGASYS": 1.000190456638056, "PEGINTRON": 1.8537703384921256, "PLAVIX": 0.4388240404802643, "RELVAR": 3.760359037113616, "ROTATEQ": 1.739382474340644, "SAXENDA": 1.0898046205479714, "SHINGRIX": 0.4013146797700126, "SIFROL": 6.481126856873063, "SOLIRIS": 0.5825887398067244, "SOMATROPIN": 4.873289348430135, "SPIKEVAX": 0.0882818804851964, "SPRYCEL": 1.1068194517142451, "STALEVO": 3.147996652888444, "STIVARGA": 2.40509063864275, "SUBOXONE": 0.5181566943490721, "SUTENT": 8.328880800552078, "TOZINAMERAN": 1.1397035409101528, "TRULICITY": 2.22811241881299, "TRUVADA": 0.3905575914020298, "VAXZEVRIA": 0.0759219070833814, "VOTRIENT": 2.503788838840824, "XALKORI": 2.673495988593454, "XELJANZ": 1.2381338608095585, "XOLAIR": 0.4465295459210646, "XTANDI": 2.564511658533738, "ZYPREXA": 1.327894259854649, "null": 1.2441269778048591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3946.json
index 4899d6da0bb..e46c5b3f9d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3946.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3946.json
@@ -1 +1 @@
-{"AIMOVIG": 5.924811631390887, "COVID19": 1.5736935717051934, "SUTENT": 2.502510690870667, "TOZINAMERAN": 1.4314636489804922, "null": 1.1080414136166787}
\ No newline at end of file
+{"null": 0.6230066376614867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3947.json
index 2ff240fa36d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3947.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3947.json
@@ -1 +1 @@
-{"ALISKIREN": 202.89714715452092, "null": 1.8550221271683172}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3948.json
index 4be92d57662..5298357bdae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3948.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3948.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 1.148417705746056, "ASPARAGINASE": 8.296364388840908, "AVASTIN": 12.723817571509231, "BEVACIZUMAB": 2.092531567619367, "BUSULFAN": 2.090967040869951, "COAPROVEL": 3.864671508894976, "CYTARABINE": 1.8001397617954318, "DEXAMETHASONE": 1.036949391577896, "EXJADE": 2.4277984382224638, "FYCOMPA": 8.345077691863196, "IRINOTECAN": 7.329392227312188, "KEPPRA": 4.216449703602315, "LENVIMA": 11.82633170608136, "LEVETIRACETAM": 9.003340065181149, "MIRABEGRON": 30.185213718404963, "NEXAVAR": 3.817834493446929, "OLANZAPINE": 3.912178137018149, "ONCASPAR": 16.736105301556027, "PANITUMUMAB": 27.327104888389982, "RISPERIDONE": 8.665817939994946, "STIRIPENTOL": 498.2714011121074, "STIVARGA": 4.869945673019456, "ZYPREXA": 1.0979555709928417, "null": 4.879844631007289}
\ No newline at end of file
+{"null": 5.809630326531971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3949.json
index 35eef6ba8b9..28c9315c5fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3949.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3949.json
@@ -1 +1 @@
-{"ASPARAGINASE": 8.295920821338791, "BEVACIZUMAB": 7.967767992182752, "BOTULINUM": 16.00685923621643, "CAPECITABINE": 6.329818278832468, "IRINOTECAN": 12.274097157135747, "LEVETIRACETAM": 14.164951703507915, "OLANZAPINE": 6.6487667932534125, "null": 6.520156493951414}
\ No newline at end of file
+{"CLOPIDOGREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/395.json
index be3b9ee5100..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/395.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/395.json
@@ -1 +1 @@
-{"ADVATE": 1.5626442432753276, "AMGEVITA": 14.08493008854426, "ASPARAGINASE": 1.666337428268396, "BEXSERO": 1.0429259583915278, "BRIDION": 48.95944933705384, "BUPIVACAINE": 1.190953569975041, "CAELYX": 3.154304234305521, "CANCIDAS": 1.3861665066828337, "CELECOXIB": 3.2133895808402717, "CHLORHEXIDINE": 3.693053332732827, "CINRYZE": 1.083946151956079, "CUBICIN": 1.0573461288095416, "DARZALEX": 1.5039748281290612, "DEXAMETHASONE": 2.7661810063802044, "DEXMEDETOMIDINE": 1.6327790250893797, "DUPIXENT": 1.237121027274965, "EMEND": 5.030237175374499, "EVUSHELD": 2.8118731507226715, "FASENRA": 4.69688118111868, "FASTURTEC": 5.574614210389711, "FENTANYL": 8.240833694520294, "FLEBOGAMMA": 3.992229157308128, "FLUCELVAX": 1.6644998619906328, "GARDASIL": 1.0219629541726196, "GAZYVARO": 1.2598620905334978, "GREPID": 5.356348745497177, "HERCEPTIN": 1.5031199987186317, "HIZENTRA": 1.4700704794140975, "HUMAN": 3.353627510609788, "HYQVIA": 1.0220546124673149, "IBUPROFEN": 2.0974637126821314, "KIOVIG": 5.221294284930504, "KUVAN": 4.3307456980514765, "LEVOFLOXACIN": 1.8167581268389592, "MANNITOL": 2.537626793672219, "MICARDIS": 1.1351682231453737, "MIDAZOLAM": 10.714035223382403, "MIRCERA": 3.3934955734555463, "MIXTARD": 1.8125719507512852, "NAGLAZYME": 1.0493447379475511, "NEULASTA": 1.8900849104672268, "NIMENRIX": 1.142298271110578, "NOT": 1.2117276312803096, "NOVOSEVEN": 2.590083057009188, "OBINUTUZUMAB": 1.7623668340145102, "OMALIZUMAB": 2.5126463308115072, "ONCASPAR": 21.36057766273677, "PARECOXIB": 46.2812076369364, "PEGASPARGASE": 2.841899556835528, "PEGFILGRASTIM": 2.145119190993866, "PERJETA": 5.249903384308326, "PIQRAY": 1.515482661329867, "PREVENAR": 2.6719949065830777, "PRIVIGEN": 3.961812408145085, "QARZIBA": 1.3831915431735398, "RIXATHON": 2.9448325292803945, "ROACTEMRA": 2.1948980630238366, "RUCONEST": 1.642940690201044, "STELARA": 1.126145554855, "SUFENTANIL": 16.49165084679229, "SUGAMMADEX": 45.18999043806067, "TAMIFLU": 1.8331063843646376, "TOCILIZUMAB": 3.16100888584066, "TORISEL": 1.9753201237961893, "TOZINAMERAN": 1.3387789187897725, "VECTIBIX": 1.0513764798465706, "VEKLURY": 1.0689391673739563, "XOLAIR": 12.053879170124592, "null": 2.5056977790544943}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3950.json
index 2f2593df8a5..d5e174b2761 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3950.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3950.json
@@ -1 +1 @@
-{"KEYTRUDA": 4.407642154162958, "NEXAVAR": 18.404690150414865, "null": 1.1503127757217606}
\ No newline at end of file
+{"ARAVA": 0.2669540124133514, "BRILIQUE": 29.826857783822657, "BRINTELLIX": 4.045384670254833, "CELLCEPT": 0.5265064245795466, "CICLOSPORIN": 0.4938033603775916, "CLOPIDOGREL": 14.273925525292594, "COMIRNATY": 0.6302294249441386, "COSENTYX": 0.6904441516328743, "CYMBALTA": 0.6226318165605499, "DEXAMETHASONE": 1.510096944408338, "DULOXETINE": 1.232408496221914, "EFIENT": 6.930246385623509, "ELIQUIS": 2.6167738051115297, "ENOXAPARIN": 17.786160944173336, "ENTRESTO": 0.7885408929169254, "EXJADE": 1.9515957078632693, "GARDASIL": 0.4489488342912841, "IBUPROFEN": 1.0832869275044823, "JAKAVI": 0.7941108768046378, "LANTUS": 0.1779783250740839, "LEVOFLOXACIN": 1.8066399160479112, "LIXIANA": 3.197845709891234, "MMRVAXPRO": 2.269324918225508, "MODERNA": 0.8392643822090449, "NEXAVAR": 0.3477302707710744, "NPLATE": 10.495947772092176, "OMALIZUMAB": 1.54533466467452, "OPTIMARK": 0.7281948722883738, "PANTOPRAZOLE": 3.4558652888961547, "PEGASYS": 0.5718526404675205, "PEGINTRON": 0.5886161444361723, "PLAVIX": 8.869862175741625, "ROACTEMRA": 1.671635532274997, "SPIKEVAX": 0.356679684686713, "SUTENT": 1.0478040468237149, "TICAGRELOR": 19.24954589386545, "TOZINAMERAN": 0.1290185405905159, "TRACLEER": 0.6845181101233835, "VAXZEVRIA": 0.8787476292234511, "VOTRIENT": 0.7236966416976528, "XARELTO": 4.354286915935052, "XELJANZ": 0.262945453994278, "XOLAIR": 0.8997303946089552, "null": 1.437726980029028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3951.json
index fd87fd0f6ff..7bea7269bfa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3951.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3951.json
@@ -1 +1 @@
-{"EMTRICITABINE": 593.189358975067}
\ No newline at end of file
+{"COMIRNATY": 0.6087218254947776, "SPIKEVAX": 19.286721630531325, "VAXZEVRIA": 0.4778713846701311, "null": 0.2300175677335202}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3952.json
index c7d56ef10b2..ec282e86363 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3952.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3952.json
@@ -1 +1 @@
-{"ABACAVIR": 2.189000727463703, "AMIKACIN": 4.180003636970371, "AMINOSALICYLIC": 1.277485044263665, "ASPARAGINASE": 9.86978245559182, "ATAZANAVIR": 38.15087120569685, "ATOSIBAN": 11.585104554602909, "AVASTIN": 1.3426518728402208, "AYVAKYT": 81.21165448975894, "AZACITIDINE": 2.2584543690588026, "BEDAQUILINE": 4.010835628548893, "BEVACIZUMAB": 3.19566443575081, "BIKTARVY": 1.7139769274036476, "BUSULFAN": 3.87806983093957, "CANCIDAS": 15.619777262057577, "CAPECITABINE": 2.616640240943848, "CASPOFUNGIN": 6.6184060113658045, "CELLCEPT": 1.0857826713576284, "CICLOSPORIN": 2.375467267908798, "CLADRIBINE": 5.348457993814543, "CLOFARABINE": 12.53120197398825, "COMBIVIR": 9.644926517629614, "CRIXIVAN": 21.636897229342207, "CUBICIN": 2.780444514671022, "CYTARABINE": 8.00340091620727, "DAKLINZA": 16.030729118149914, "DEXAMETHASONE": 2.529004150628658, "EMTRICITABINE": 8.678625914807302, "ENOXAPARIN": 2.4641956367146447, "EPIVIR": 8.815671634720543, "EXJADE": 3.5911029552396547, "EXVIERA": 72.20944292212168, "HALAVEN": 2.5689827564013554, "HARVONI": 4.510867606832952, "HERCEPTIN": 1.6217815496522476, "IBUPROFEN": 1.4931445427322567, "INCIVO": 2.2880024339723497, "INDINAVIR": 15.098558188528974, "IPILIMUMAB": 1.2120126076834157, "IRINOTECAN": 1.88558271547872, "ISENTRESS": 7.20478294102445, "JANUVIA": 1.063150919044834, "KAFTRIO": 14.2892959181756, "KALETRA": 11.241384669984058, "KISQALI": 1.706777479332821, "KIVEXA": 18.051900573636303, "KYMRIAH": 1.2520793224073157, "LACOSAMIDE": 2.737058832351046, "LAMIVUDINE": 3.627244885292161, "LITAK": 45.972828608775394, "LONSURF": 2.556312633099909, "MERCAPTOPURINE": 5.766278859221334, "METHOTREXATE": 1.733352622698144, "MIDAZOLAM": 1.3584058484549235, "NEXAVAR": 4.206334954951767, "NILOTINIB": 13.603184943644372, "NORVIR": 42.8540899561524, "NOXAFIL": 12.02073830328612, "OCALIVA": 7.373711556774623, "OLYSIO": 61.468550347275226, "ONCASPAR": 9.594333350376742, "PAZOPANIB": 8.237906255736153, "PEGASYS": 1.6404982371994563, "PEGINTERFERON": 4.504520115829125, "PEGINTRON": 1.870137747155411, "POSACONAZOLE": 5.946134570743815, "PROPRANOLOL": 5.243791039753565, "REBETOL": 8.776697948270735, "REYATAZ": 98.03927409503956, "RIBAVIRIN": 9.310040241056877, "SIMEPREVIR": 37.07307716573468, "SOLIRIS": 1.0962132815950143, "SOVALDI": 19.273544181611605, "STIVARGA": 8.973271325476142, "TAMIFLU": 1.1493113617497743, "TASIGNA": 7.654302023865514, "VFEND": 2.196505667397472, "VORICONAZOLE": 1.8600283585809296, "VOTRIENT": 4.75756366774999, "XELODA": 3.171059135469399, "YESCARTA": 3.793739634463942, "ZELBORAF": 2.8194306687265214, "null": 1.086074834359393}
\ No newline at end of file
+{"ARIPIPRAZOLE": 35.334604193127, "COMBIVIR": 14.1774643664846, "COMIRNATY": 0.8816116601962013, "SPIKEVAX": 2.54278772922082, "TRACLEER": 8.83963864030103, "null": 0.7624052675574188}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3953.json
index 55fa3646b56..01e46e6cffd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3953.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3953.json
@@ -1 +1 @@
-{"LANTUS": 5.983111762565416, "SUBOXONE": 16.18633658084823, "null": 1.6529040897327385}
\ No newline at end of file
+{"SPIKEVAX": 22.567089862596283}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3954.json
index c560d12a3f9..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3954.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3954.json
@@ -1 +1 @@
-{"ABATACEPT": 3.2440785709175644, "ADALIMUMAB": 3.883461725655418, "AFINITOR": 1.3367176153431668, "APREMILAST": 16.766447692907377, "AZATHIOPRINE": 2.5112646875090454, "BIKTARVY": 7.541415654461298, "BONVIVA": 10.33021937226971, "BORTEZOMIB": 7.89263979461127, "BUSULFAN": 1.9996396962485372, "BYETTA": 1.8795497865227455, "CANCIDAS": 6.249907200072996, "CELECOXIB": 4.4704417593419885, "CELLCEPT": 1.845530770700939, "CICLOSPORIN": 1.8071860356396348, "CINACALCET": 74.16233246502723, "COAPROVEL": 3.539420538430375, "CYTARABINE": 1.263644530978995, "DARZALEX": 2.348415920305669, "DASATINIB": 6.843970899264061, "DENOSUMAB": 5.607487301895458, "DEXAMETHASONE": 1.7516849675174238, "ENBREL": 14.266525093350074, "EVENITY": 8.224792986348008, "EVISTA": 3.0336295083060096, "FASLODEX": 2.2689823800182225, "FORSTEO": 28.35482959898496, "HYDROXOCOBALAMIN": 408.7547512422973, "IBRANCE": 1.0780612658630648, "INLYTA": 2.340213581533172, "IPILIMUMAB": 1.6978739170050294, "IRBESARTAN": 3.228570718867339, "KEYTRUDA": 1.7443619610343672, "KYPROLIS": 4.883966232416806, "LENVIMA": 2.2987456275342466, "MEKINIST": 1.0119357534100284, "MIMPARA": 58.74948521661065, "MOVYMIA": 21.41948279786065, "OPDIVO": 2.2228626430324225, "PANTOPRAZOLE": 3.4644149399409105, "PEGINTERFERON": 1.662832818651434, "POTELIGEO": 18.129281781054377, "PREOTACT": 273.23643781903644, "REVLIMID": 4.231681543534475, "SUTENT": 1.1575612783114058, "TELMISARTAN": 8.75568038213015, "TERIPARATIDE": 76.67013068304536, "TORISEL": 3.94342967994974, "VELTASSA": 3.483191689112846, "VENCLYXTO": 5.942842772370103, "VENETOCLAX": 4.06566124306363, "VORICONAZOLE": 3.7060830466172767, "ZOLEDRONIC": 39.44529671253941, "null": 1.4766591516733691}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3955.json
index b2194ec64b7..37989560261 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3955.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3955.json
@@ -1 +1 @@
-{"FORSTEO": 39.98048944320949, "null": 2.611264679283238}
\ No newline at end of file
+{"null": 4.91065573488685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3956.json
index 4a4b472f5a6..caf79ef26f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3956.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3956.json
@@ -1 +1 @@
-{"ACLIDINIUM": 87.65943224161082, "ARIPIPRAZOLE": 4.559236591096972, "BUPRENORPHINE": 2.860313541766849, "CASPOFUNGIN": 19.25129509686071, "CICLOSPORIN": 1.050965667086039, "CLOPIDOGREL": 1.407620979146679, "DEXAMETHASONE": 2.49655652406694, "FENTANYL": 18.248957998829145, "HYDROCORTISONE": 14.751160631951256, "KEYTRUDA": 1.1814047176419815, "LEVETIRACETAM": 3.568336968158876, "MIDAZOLAM": 25.769717377265444, "NORVIR": 12.482923692416897, "OPSUMIT": 4.335594664602928, "PREGABALIN": 8.025811553870865, "REVATIO": 7.790111372883434, "ZYPREXA": 4.593318771609615, "null": 1.9712160069780345}
\ No newline at end of file
+{"null": 1.4595297982745308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3957.json
index e302da664a7..28392b2ef5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3957.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3957.json
@@ -1 +1 @@
-{"null": 3.2440154132938024}
\ No newline at end of file
+{"INVEGA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3958.json
index 4f8ffb74b0f..3b22b0a95bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3958.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3958.json
@@ -1 +1 @@
-{"null": 3.617785709438192}
\ No newline at end of file
+{"null": 3.94128261155143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3959.json
index 3193ff71a98..7d90db1f359 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3959.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3959.json
@@ -1 +1 @@
-{"ESBRIET": 9.085421203680363, "IBRANCE": 2.458552519735249, "JANUMET": 9.334841391426938, "SAXENDA": 9.95746035965688, "SUTENT": 16.614087871867753, "null": 1.2668135275374248}
\ No newline at end of file
+{"ABILIFY": 1.7827524850640986, "ATRIPLA": 51.50536875963143, "BUPRENORPHINE": 1.342312691407651, "COMIRNATY": 0.003274133330675, "KALETRA": 2.509315768417807, "PLAVIX": 1.0405969282601022, "SIFROL": 2.3264920782076506, "STRIBILD": 47.41659546093008, "SUBOXONE": 0.4112254271662045, "TRUVADA": 29.370968323767038, "VIREAD": 21.96826897371798, "null": 0.6483491216361346}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/396.json
index a73009a0478..c142b5287b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/396.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/396.json
@@ -1 +1 @@
-{"ALIMTA": 1.0378390679784324, "ASPARAGINASE": 1.543444709503757, "AVASTIN": 1.867575621684452, "BONVIVA": 1.3697328333756724, "BRIDION": 62.63059390038672, "CAELYX": 2.5660765514582184, "CEFUROXIME": 14.998257129528922, "CHLORHEXIDINE": 2.5377056795273143, "CUBICIN": 1.173395950832845, "DARZALEX": 1.0023008569383431, "DEXAMETHASONE": 3.6087063386861833, "DEXDOR": 11.185645503700629, "DEXMEDETOMIDINE": 2.6236905544891456, "EMEND": 2.1454589944833344, "ERBITUX": 2.1832359194945603, "FASTURTEC": 16.892588066902487, "FENTANYL": 5.619690709521088, "FLEBOGAMMA": 1.3116786745463622, "GAZYVARO": 1.5377202896978035, "GLUCAGON": 2.314713020934067, "HERCEPTIN": 1.10653145668034, "KIOVIG": 3.8399960865024623, "LEVOFLOXACIN": 2.86058351795023, "MIDAZOLAM": 14.79348965057818, "MIRCERA": 2.231083079273147, "MIXTARD": 2.9126298870710503, "NOT": 1.433254820270035, "ONCASPAR": 8.05132336096863, "PERJETA": 5.335533042116636, "PRIVIGEN": 1.0346159859825956, "RIXATHON": 1.7050380910068694, "ROACTEMRA": 1.535551480132082, "SUFENTANIL": 109.9967214958737, "SUGAMMADEX": 25.2329362032695, "TAMIFLU": 1.499253768379376, "XOLAIR": 1.7046836233767333, "null": 6.62077176035986}
\ No newline at end of file
+{"null": 1.395000896118496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3960.json
index fec7d1f5ad4..edf99774475 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3960.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3960.json
@@ -1 +1 @@
-{"ABACAVIR": 2.5043014690160077, "ABATACEPT": 21.11295101876185, "ADALIMUMAB": 8.361792741822832, "AFINITOR": 4.382970083063183, "APREMILAST": 3.1427390531804567, "ARAVA": 4.321248847843233, "ARIPIPRAZOLE": 1.953604841653125, "ATAZANAVIR": 2.43929409792802, "AVANDIA": 1.8982446268386932, "BIKTARVY": 2.1680425463694517, "BYDUREON": 3.685883396518293, "BYETTA": 9.085032833508189, "CAPECITABINE": 4.311590540912288, "CELLCEPT": 1.7890915721309464, "CERTOLIZUMAB": 29.157764496522365, "CICLOSPORIN": 1.566943626000337, "CIMZIA": 1.40918772660622, "COMBIVIR": 4.236795279306797, "CRIXIVAN": 21.435091590214903, "EMTRIVA": 24.183076725052317, "ENBREL": 3.911389547997099, "EPIVIR": 14.79790248279143, "EXFORGE": 1.4118770359941175, "FASLODEX": 1.077250335517988, "GENVOYA": 11.364104759277613, "GLYCOPYRRONIUM": 80.32487096122237, "HYDROCORTISONE": 3.2245078471824704, "INTELENCE": 20.331408852927524, "INVIRASE": 29.71684111750704, "JAKAVI": 1.7248335178269396, "JANUMET": 6.74046109121503, "JANUVIA": 5.513922783639032, "KALETRA": 4.609767340027047, "LAMIVUDINE": 10.348829177875848, "MEPOLIZUMAB": 1.044418217979224, "MIRABEGRON": 17.775597585053816, "MYCOPHENOLATE": 2.7622384369120505, "NILOTINIB": 10.103422689135725, "NORVIR": 3.832174146612736, "OLANZAPINE": 1.8408996369108896, "ONCASPAR": 4.941555833393443, "PANTOPRAZOLE": 2.142046353793268, "RINVOQ": 5.744124232022465, "ROACTEMRA": 12.080394971391984, "SYMTUZA": 53.33628903283755, "TASIGNA": 9.74211879235081, "TOCILIZUMAB": 6.712580878038252, "ZOSTAVAX": 5.684071235337333, "ZYPREXA": 8.911636697864235}
\ No newline at end of file
+{"DEXAMETHASONE": 22.86960049905417, "null": 0.7750918488004754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3961.json
index 68b21697d35..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3961.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3961.json
@@ -1 +1 @@
-{"COMBIVIR": 185.9864470141101}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3962.json
index 1cff65d99c9..5b5a98deb97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3962.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3962.json
@@ -1 +1 @@
-{"ELIQUIS": 4.321149540026172, "HUMALOG": 2.9039535676329997}
\ No newline at end of file
+{"CAPECITABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3963.json
index adeab008977..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3963.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3963.json
@@ -1 +1 @@
-{"TRUVADA": 4.9373847004101705, "null": 1.0524055819403504}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3964.json
index 099b5cec8e7..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3964.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3964.json
@@ -1 +1 @@
-{"PEMETREXED": 55.48299098868674, "SUTENT": 2.9382717978859705, "null": 1.2303876535239746}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3965.json
index 5a0570c9ae0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3965.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3965.json
@@ -1 +1 @@
-{"FENTANYL": 25.32730947348779, "null": 1.9937791228351505}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3966.json
index 0762df8921b..27fd32520d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3966.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3966.json
@@ -1 +1 @@
-{"BIKTARVY": 47.90612869601023, "null": 1.0021224330468554}
\ No newline at end of file
+{"COMIRNATY": 0.4409701483592925, "CYMBALTA": 5.415066480153956, "ELLAONE": 92.73931409255113, "EVRA": 37.73428142583202, "FASENRA": 10.075088557562072, "FOLLITROPIN": 682.5412023326703, "GARDASIL": 2.4706034617320998, "GNRHANALOG": 32649.084267910934, "GONALF": 96.92512928260922, "KEPPRA": 2.087263774987293, "PEGASYS": 1.3503773013635554, "PUREGON": 228.98950167502068, "SPIKEVAX": 0.1888333301987476, "SUBOXONE": 3.814687570136633, "TOZINAMERAN": 0.7112567824630076, "VAXZEVRIA": 0.1305187484635669, "null": 1.0472343725958866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3967.json
index e33c81ea436..c6945765257 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3967.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3967.json
@@ -1 +1 @@
-{"NUCALA": 21.410970149285266, "null": 1.0333323931531104}
\ No newline at end of file
+{"null": 4.084932439899535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3968.json
index fdffa6dd24c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3968.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3968.json
@@ -1 +1 @@
-{"null": 1.7203581838430817}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3969.json
index b58ac2c99c3..90798fc7b41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3969.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3969.json
@@ -1 +1 @@
-{"null": 1.172994818700057}
\ No newline at end of file
+{"null": 2.269086490314122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/397.json
index 8f17f1f6157..2d985c0a53f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/397.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/397.json
@@ -1 +1 @@
-{"ALIMTA": 1.1426141472628624, "ASPARAGINASE": 2.073248773058864, "AVASTIN": 5.713601580506567, "BRIDION": 44.80322535895784, "CAELYX": 5.894912179903048, "DARZALEX": 2.5474246826309743, "DEXAMETHASONE": 1.2521257418223954, "FASENRA": 1.3825163483021965, "FASLODEX": 1.3474325111585848, "FENTANYL": 7.430705083076045, "FLEBOGAMMA": 6.163378161538409, "HUMAN": 9.077106355714786, "ISOPHANE": 19.088555070127462, "KIOVIG": 17.596572886453956, "LEVOFLOXACIN": 4.339935132695832, "MIDAZOLAM": 8.223422863063975, "PRIVIGEN": 3.1710018807822, "ROACTEMRA": 2.5075888989323065, "STELARA": 1.0277800960126706, "SUFENTANIL": 19.71177305225272, "TAMIFLU": 3.8301099961695777, "XOLAIR": 3.496956817012715, "null": 5.107694725197075}
\ No newline at end of file
+{"COMIRNATY": 0.4828381944274298, "null": 0.4740845503240524}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3970.json
index 091f6e402cf..abdf473ac96 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3970.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3970.json
@@ -1 +1 @@
-{"null": 6.302341794921743}
\ No newline at end of file
+{"BUDESONIDE": 52.59503626972936, "null": 0.9204849839903791}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3971.json
index 15334ce1442..0d4f33f246b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3971.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3971.json
@@ -1 +1 @@
-{"ABASAGLAR": 16.96847515543729, "ACTOS": 2.503913701173462, "ACTRAPID": 21.794126062401197, "AFINITOR": 5.648373004664907, "ALL": 2.932935963249306, "ALPELISIB": 66.83909950677229, "APIDRA": 46.0319744874429, "APROVEL": 2.458433156127104, "ASPARAGINASE": 3.2303632958598945, "BLINATUMOMAB": 8.179014744524643, "BUDESONIDE": 3.639015147468984, "BYDUREON": 1.3291172788585337, "BYETTA": 2.918997002838631, "CANAGLIFLOZIN": 25.853280399146083, "COAPROVEL": 2.199444625078534, "CORTICOSTEROID": 5.656524775072676, "CORTICOSTEROIDS": 5.122187241592768, "CRIXIVAN": 4.466980246257307, "CYTARABINE": 1.3953438927045263, "DAPAGLIFLOZIN": 5.839174150484727, "DENOSUMAB": 1.5171072249204305, "DEVICE": 59.36372930017131, "DEXAMETHASONE": 1.5529892513225425, "EMPAGLIFLOZIN": 2.95399909357365, "EPIVIR": 1.5243187942068923, "EUCREAS": 3.517447406920152, "EXUBERA": 12.53631536929412, "FIASP": 40.09639672669617, "FORXIGA": 6.583103900314509, "FULVESTRANT": 2.7489752485532386, "GALVUS": 3.7372087191152663, "GLIBENCLAMIDE": 4.706674707957352, "GLUCAGON": 3.664733570106926, "HALAVEN": 1.3383404165040558, "HARVONI": 1.0931215135012915, "HUMALOG": 12.63845637842158, "HYDROCHLOROTHIAZIDE": 2.5795252685950327, "INSULATARD": 20.059590601447745, "INSULIN": 21.228420769716006, "INSUMAN": 18.465977341689065, "INTEGRILIN": 2.135309826814493, "INVIRASE": 2.6513000513292195, "INVOKANA": 4.322530604586033, "ISOPHANE": 5.706997139697428, "JANUMET": 3.113214803658157, "JANUVIA": 1.9860854996642776, "JARDIANCE": 2.4274590458928684, "LANTUS": 37.92088185974232, "LEVEMIR": 11.34060881009752, "LIPROLOG": 6.932135829706606, "LIRAGLUTIDE": 2.461384559735168, "LUTATHERA": 1.6203456668376857, "LYUMJEV": 16.941635120085436, "METFORMIN": 5.702916967877856, "MICARDIS": 1.0017120963916228, "MIXTARD": 57.06103805491388, "MYCOPHENOLATE": 1.0191384368087693, "NILOTINIB": 1.577655495030541, "NOVOMIX": 8.589314474132722, "NOVONORM": 8.824095389220867, "NOVORAPID": 83.28236223461992, "OBINUTUZUMAB": 1.2432900008905043, "OCTREOTIDE": 6.794022826848816, "OLANZAPINE": 1.6725659573939216, "ONCASPAR": 3.013646663986965, "ONGLYZA": 2.9168262852476614, "PASIREOTIDE": 27.339750345512016, "PIOGLITAZONE": 2.5777670484436626, "PIQRAY": 90.6698687634995, "PROTAPHANE": 13.65645944061656, "RASILEZ": 1.0074552626383135, "REPAGLINIDE": 4.522722420950192, "RISPERIDONE": 1.3563433689674127, "RYBELSUS": 1.7180256874357005, "SIGNIFOR": 46.301680078031445, "TASIGNA": 1.69651532254808, "TIVICAY": 1.4203486918631285, "TORISEL": 3.779807369931933, "TOUJEO": 25.28186019143705, "TRESIBA": 23.67249654949432, "TRULICITY": 1.575333486536053, "VICTOZA": 1.900107580075146, "VILDAGLIPTIN": 3.876675118939951, "ZYPREXA": 8.739558623725001}
\ No newline at end of file
+{"null": 1.4293166421256611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3972.json
index 11b1abcbe7b..6752aec190f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3972.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3972.json
@@ -1 +1 @@
-{"FORXIGA": 37.898165800217264, "ICOSAPENT": 2439.3512547825017, "JARDIANCE": 27.519081179378546, "OLANZAPINE": 12.930321377973245, "PIQRAY": 217.3686244158599, "ZYPREXA": 17.029439724273008}
\ No newline at end of file
+{"TOBRAMYCIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3973.json
index 5014bd6abb7..faba14b0bf9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3973.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3973.json
@@ -1 +1 @@
-{"HUMALOG": 39.040399199190375, "LANTUS": 33.81586402493104, "LEVEMIR": 88.43868834814944, "NOVORAPID": 34.30867187137813}
\ No newline at end of file
+{"ABACAVIR": 0.1833740106115377, "ADALIMUMAB": 0.7140179478163053, "AERIUS": 5.517817072753864, "AFINITOR": 0.492846517646705, "AIMOVIG": 0.5991748188908156, "ALDARA": 2.182924149825864, "ALIMTA": 0.469130242999444, "APIDRA": 0.4506634010925436, "APIXABAN": 0.2082311580274015, "APROVEL": 3.733806859456663, "ARANESP": 0.6620484466837958, "ARAVA": 0.195372487754057, "ASPARAGINASE": 1.2612768591252888, "AUBAGIO": 1.5320812621952289, "AVAMYS": 16.333681970207188, "BENLYSTA": 0.3886827962087348, "BEXSERO": 2.4000514267783606, "BIKTARVY": 0.5224996364617153, "BONVIVA": 1.6807106182949785, "BOSULIF": 1.0648088557645996, "BRILIQUE": 1.054945929105427, "BRINTELLIX": 0.7949996216145478, "BUDESONIDE": 0.9552758249195548, "BUPRENORPHINE": 0.4220157972398552, "BYDUREON": 0.3799674407256223, "CABOMETYX": 0.7210495065207538, "CAPECITABINE": 0.5093329163728173, "CELLCEPT": 0.1872955006766868, "CHAMPIX": 1.1868381806396986, "CICLOSPORIN": 0.6336839543386406, "CIMZIA": 0.7546848802689063, "CLOPIDOGREL": 0.9176184995378422, "COAPROVEL": 2.303061066754511, "COMIRNATY": 1.027093028781657, "COMPRESSION": 56.141500484418025, "COSENTYX": 3.6484207690903614, "CUBICIN": 0.8693446514761144, "CYMBALTA": 0.4836546519978482, "DULOXETINE": 1.1164537076642915, "DUPIXENT": 3.694088681694117, "ELIQUIS": 1.2552668468969783, "ENTRESTO": 0.7800934861642306, "ENTYVIO": 1.3708332282916167, "ERLEADA": 3.123227063737258, "ESBRIET": 0.4610668045649689, "EUCREAS": 3.4967921072958306, "EXFORGE": 1.1976759725486583, "FASENRA": 2.592598906285132, "FASLODEX": 0.3217266489235685, "FENTANYL": 0.146186276134371, "FLEBOGAMMA": 1.93132124193378, "FLUTICASONE": 3.3260488589173933, "FORSTEO": 0.407089272974969, "FORXIGA": 0.7066243804069486, "GALVUS": 4.106727674208305, "GARDASIL": 1.400154335914165, "HARVONI": 0.4788989426782881, "HIZENTRA": 1.554767469840967, "HUMALOG": 0.3974315157598313, "HUMAN": 1.5556113008770265, "HUMIRA": 0.7483655574000203, "HYDROCORTISONE": 5.522840295222628, "IBRANCE": 0.2396040493774219, "ICLUSIG": 1.3225582418364434, "INCIVO": 3.3150302754689247, "INFANRIX": 2.3981527868361106, "INLYTA": 0.5495611762713736, "IRBESARTAN": 3.2869846394520734, "IRESSA": 2.935566774734069, "JANUMET": 0.883239075518069, "JANUVIA": 1.1623244725695752, "JARDIANCE": 0.8929184235423377, "KEPPRA": 1.014946886226609, "KEYTRUDA": 1.1595148739425192, "KISQALI": 0.7085624384168765, "LANTUS": 0.1335114382679368, "LEVETIRACETAM": 1.058300386526883, "LEVOFLOXACIN": 0.4555068707287485, "LIXIANA": 0.9489393011323156, "LYRICA": 0.5368838771614699, "MEKINIST": 0.8076401469339417, "MEPOLIZUMAB": 6.198317509933217, "METFORMIN": 4.663305494999279, "METHOTREXATE": 0.8506704115125012, "MICARDIS": 1.2680776343847864, "MMRVAXPRO": 3.418287827688867, "MODERNA": 1.1108082316049168, "MULTAQ": 0.7702683758341895, "NEXAVAR": 0.9134098538320508, "NIMENRIX": 0.6786297024565382, "NOVONORM": 5.52689235654284, "NUCALA": 3.316493324358444, "OLANZAPINE": 0.2933791425218894, "OLYSIO": 2.2986677950224768, "OMALIZUMAB": 1.2929323505561268, "OPDIVO": 0.8628245252872387, "OPSUMIT": 0.2088495322210837, "PANTOPRAZOLE": 1.2277546492761149, "PEGASYS": 1.9278619841948728, "PEGINTERFERON": 1.7078138021944285, "PEGINTRON": 1.2435174416241732, "PEMBROLIZUMAB": 1.247001965642912, "PLAVIX": 0.8919736785117658, "PREVENAR": 2.9614984590522613, "PRIVIGEN": 4.763348387309782, "PROTELOS": 5.914249164916635, "PROTOPIC": 8.849080407545403, "REBETOL": 1.5403423696744805, "RELVAR": 1.8213650783488144, "REMICADE": 1.49321342342815, "RIBAVIRIN": 1.5075897030255183, "RINVOQ": 3.224190553330547, "RITUXIMAB": 0.256264348742112, "ROACTEMRA": 1.450490803595924, "ROTATEQ": 1.2728978634550112, "SHINGRIX": 1.4600035966266554, "SIMPONI": 0.8367105351828994, "SKYRIZI": 4.999146028610052, "SPIKEVAX": 0.6602299042777098, "SPRYCEL": 0.330253686042703, "STELARA": 1.735941032107058, "STIVARGA": 0.6181472172254487, "SUTENT": 0.2130633127757348, "SYNAGIS": 0.7082700893818681, "TAGRISSO": 1.1939640983164954, "TAMIFLU": 1.2828681906044308, "TASIGNA": 0.5397816408034894, "TOCOPHEROL": 15.21187802587053, "TOZINAMERAN": 0.8325404245416603, "TREMFYA": 3.8306850009236575, "TRULICITY": 0.3584077250194837, "TWINRIX": 2.5250214162206124, "VAXZEVRIA": 0.4290801149156312, "VIAGRA": 0.3909335792780851, "VIMPAT": 0.8367009541504259, "XARELTO": 0.5741126721161737, "XELJANZ": 0.3735270518086814, "XOLAIR": 1.7772026315331657, "ZINBRYTA": 10.35389393301356, "ZOSTAVAX": 1.5193306233906698, "ZYPREXA": 0.1559895147304915, "null": 1.1840792087068206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3974.json
index aae74a0243f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3974.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3974.json
@@ -1 +1 @@
-{"null": 1.1754565013842662}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3975.json
index 39d3f650e21..21356241bbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3975.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3975.json
@@ -1 +1 @@
-{"ABACAVIR": 6.291607386652432, "ACLIDINIUM": 1.180085048508101, "ACTOS": 1.0281060853638608, "ACTRAPHANE": 3.458195749106008, "ACTRAPID": 1.5173443757157183, "AGOMELATINE": 3.735703102688356, "APIDRA": 2.609194761429089, "APIXABAN": 1.5488049227493983, "ARSENIC": 3.787697675690107, "AZILECT": 1.48797873277654, "BOTULINUM": 7.286541101475322, "BRINTELLIX": 2.3676515431707954, "BUPIVACAINE": 1.140448686911809, "BUPRENORPHINE": 1.3205354686405697, "BUVIDAL": 2.217549279028442, "CHAMPIX": 1.2010966797138944, "CLOPIDOGREL": 1.408839406151829, "COMTAN": 1.0361070429474526, "COVID19": 2.775170598643258, "CYMBALTA": 4.670875436889571, "DAPAGLIFLOZIN": 1.0109522441807268, "DULOXETINE": 1.386117617145698, "ENTACAPONE": 1.205526824067229, "ESOMEPRAZOLE": 1.232516640402546, "FASTURTEC": 2.6947521239337107, "FLEBOGAMMA": 2.280769236112001, "FORSTEO": 1.847594682234163, "GALAFOLD": 1.103246988164163, "GALVUS": 1.0374221613118482, "GARDASIL": 1.197184762162084, "GAZYVARO": 2.236148330981218, "GLIBENCLAMIDE": 1.6407641973720184, "GUANFACINE": 4.218709718398258, "HUMALOG": 1.3109400553811108, "IBUPROFEN": 1.0123727710633246, "ILARIS": 5.044083264446504, "INSULIN": 1.7608668265057124, "INSUMAN": 1.472103925024948, "INVEGA": 1.0478522711028586, "KIOVIG": 1.0371108218851637, "LANTUS": 2.5936102028849457, "MANNITOL": 1.3895013459973364, "MENVEO": 1.1091303170643916, "MICARDIS": 1.130870291561735, "MICARDISPLUS": 1.916818938657884, "MIRCERA": 1.6121199443906824, "MIXTARD": 1.070156718773339, "MOVYMIA": 1.8357237823010435, "NIVESTIM": 1.6468692837230088, "NOVONORM": 1.991471855560976, "OLANZAPINE": 1.1157546741298383, "ORENCIA": 2.060605839325512, "PIOGLITAZONE": 1.386110779452827, "PRAMIPEXOLE": 3.4731125668744016, "PRIVIGEN": 1.3578494664490597, "RANEXA": 2.028537912237953, "REPAGLINIDE": 1.446237805317095, "RIXATHON": 1.5728162292355208, "RYEQO": 1.7111708493979103, "SELINCRO": 3.3945568991737725, "SEMAGLUTIDE": 8.677378671384481, "SOMAVERT": 1.920774238476125, "SPIKEVAX": 1.1972403664094702, "SUBOXONE": 1.9887398919114685, "TELMISARTAN": 1.0365337131990902, "TICAGRELOR": 1.342563436066056, "TOUJEO": 1.2152913963727874, "TOZINAMERAN": 1.5775559917778097, "TWINRIX": 1.686682074782277, "VALDOXAN": 2.433444165727105, "VAXZEVRIA": 1.701376851423265, "VILDAGLIPTIN": 1.4853870546587655, "VORTIOXETINE": 5.7943674053066045, "XYREM": 1.145712208670108, "ZARZIO": 1.5686171027404074, "ZYPADHERA": 1.0806054775440377, "null": 1.054094195686389}
\ No newline at end of file
+{"COMIRNATY": 0.3483788129800211, "PEGINTRON": 8.603176086683266, "VAXZEVRIA": 0.5526027583009983, "null": 0.4959346955042564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3976.json
index 0ff3bd8b222..4467558caf5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3976.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3976.json
@@ -1 +1 @@
-{"INSULIN": 27.491114252306765, "LANTUS": 5.084539383752847, "null": 1.4982465487497445}
\ No newline at end of file
+{"COMIRNATY": 1.2170659532869068, "SPIKEVAX": 0.7001184488685539, "null": 1.5674726001540875}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3977.json
index 47e20de5588..822693f0365 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3977.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3977.json
@@ -1 +1 @@
-{"ABASAGLAR": 65.58767067997874, "ACTRAPID": 48.3005349599956, "APIDRA": 69.5945885267812, "HUMALOG": 60.11258375732549, "INSULIN": 26.22679902043395, "LANTUS": 35.51893406154218, "LEVEMIR": 13.556973157449654, "NOVORAPID": 23.778744399440228}
\ No newline at end of file
+{"CICLOSPORIN": 6.070967534603952, "COMIRNATY": 0.255826487817864, "PROTOPIC": 433.5683513177272, "RINVOQ": 251.4088891281736, "SPIKEVAX": 0.4391022753877929, "UPADACITINIB": 420.7021269661533, "null": 0.4867224300034673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3978.json
index 93beb9ff4da..c22e9e7016e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3978.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3978.json
@@ -1 +1 @@
-{"null": 1.6222395180044056}
\ No newline at end of file
+{"COMIRNATY": 0.9419801979422652, "null": 0.5983697338738411}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3979.json
index eba4de0dff4..110ab46e17a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3979.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3979.json
@@ -1 +1 @@
-{"null": 3.9356187523285056}
\ No newline at end of file
+{"COMIRNATY": 1.4855579025031769, "SPIKEVAX": 0.8067228910518182, "TREMFYA": 29.826567259542028, "VAXZEVRIA": 0.3844319505512226, "null": 0.5427472013377506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/398.json
index cb45f592358..acfe7238125 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/398.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/398.json
@@ -1 +1 @@
-{"BRIDION": 36.34403319582919, "DEXAMETHASONE": 10.887872550506422, "FENTANYL": 3.826588555309565, "MIDAZOLAM": 26.216892794461685, "SUFENTANIL": 212.05232038263395, "null": 5.730523357847515}
\ No newline at end of file
+{"null": 2.386097647336676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3980.json
index 1c390ac48a3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3980.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3980.json
@@ -1 +1 @@
-{"ACE": 7.974255272199924, "ACTOS": 1.825331454837455, "ACTRAPID": 1.033233262518701, "ADENURIC": 9.7812557148707, "ADVAGRAF": 2.963279342738166, "AERIUS": 1.38744498816401, "ALISKIREN": 3.851214217571012, "APREMILAST": 1.1566095556224931, "APROVEL": 30.771762256957366, "ARIPIPRAZOLE": 1.8578972723745792, "AXITINIB": 1.9900543543100015, "BENZODIAZEPINE": 2.923089158744986, "BEXTRA": 3.559725561765743, "BINOCRIT": 4.1854908015195935, "BUMETANIDE": 14.939793212633624, "BYETTA": 1.0520853196596045, "CABOMETYX": 1.0318762837674569, "CELECOXIB": 1.989354892635645, "CELLCEPT": 1.5444945215725303, "COAPROVEL": 14.102096608080023, "CUBICIN": 3.0156361075387403, "DAPAGLIFLOZIN": 5.789084522994558, "DELAMANID": 1.2628517482833232, "DENOSUMAB": 1.7647452106067216, "DUOPLAVIN": 19.34434890240969, "EDOXABAN": 7.934366362558093, "EMPAGLIFLOZIN": 4.006720734983727, "EMTRICITABINE": 1.464419895994319, "EMTRIVA": 3.2492427253827123, "ENALAPRIL": 6.505488191029216, "ENOXAPARIN": 1.0349631480906585, "ENTRESTO": 19.19636968435838, "ERBITUX": 1.8339425466940331, "ESOMEPRAZOLE": 3.05422954871171, "EUCREAS": 10.712512431115888, "EVRENZO": 35.18193331870564, "EXFORGE": 5.860577757065849, "EXVIERA": 2.613354738259977, "FEBUXOSTAT": 3.0064749936535566, "FORXIGA": 2.480542075197812, "GALVUS": 1.2334517127963356, "GLUCAGON": 6.979467708295187, "HYDROCHLOROTHIAZIDE": 4.6060379624442, "IBUPROFEN": 2.5382969068128, "INVOKANA": 4.750934652391743, "IRBESARTAN": 16.410012004643523, "IRON": 2.151128143043236, "ISOPHANE": 4.729444417139543, "JANUMET": 2.207212455315605, "JANUVIA": 1.7416978106769307, "JARDIANCE": 1.4685956262541682, "KARVEA": 26.84115267850989, "KARVEZIDE": 12.970275288876197, "KERENDIA": 100.97790017031684, "LAMIVUDINE": 1.0058669554303206, "LIRAGLUTIDE": 1.8706286812082256, "LUPKYNIS": 3.2292311509411893, "LYRICA": 1.2245863741425247, "METFORMIN": 3.837990250128751, "MICARDIS": 14.4966059202757, "MICARDISPLUS": 8.32197494230159, "MIDAZOLAM": 1.2987596587972845, "MIMPARA": 2.333956010667844, "MYCOPHENOLATE": 1.5655196660468786, "NO": 11.223407434579828, "NOT": 1.3320651239660837, "NOVONORM": 5.269981239572672, "PANTOPRAZOLE": 2.0032822689240697, "PRADAXA": 3.3388951275698764, "PRITOR": 10.57789017706332, "PROCORALAN": 11.59852231678672, "PROPRANOLOL": 1.195163902990167, "RASBURICASE": 13.236460270616377, "RASILEZ": 17.155751588825034, "REMDESIVIR": 2.961959490168129, "REPAGLINIDE": 5.779241485716969, "SAMSCA": 19.29357378860546, "SAXAGLIPTIN": 18.62037132838603, "SITAGLIPTIN": 6.01427606706304, "SOVALDI": 1.3425157070610796, "SPIRONOLACTONE": 53.296380247026285, "TACROLIMUS": 9.20247570669359, "TEKTURNA": 6.718978229010968, "TELMISARTAN": 10.287335806164004, "TORISEL": 2.122195026933143, "TWYNSTA": 8.554381585502908, "VALSARTAN": 22.42117994810287, "VELMETIA": 4.129412199973573, "VELTASSA": 5.958558051814749, "VENCLYXTO": 1.4909647768106076, "VENETOCLAX": 1.1298678269454427, "VFEND": 1.51314436980094, "VIEKIRAX": 37.21698331899839, "VILDAGLIPTIN": 3.9967030013145792, "XARELTO": 1.4972257564572693, "XELEVIA": 23.125419839169584, "null": 3.874320612166048}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3981.json
index 4314ffa2c64..fb5a17f0407 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3981.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3981.json
@@ -1 +1 @@
-{"null": 1.016791246989776}
\ No newline at end of file
+{"null": 1.1637784968729086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3982.json
index d4e206de8b2..9d30b51e65e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3982.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3982.json
@@ -1 +1 @@
-{"AFINITOR": 1.232475777040389, "CABOMETYX": 13.13184889222622, "CICLOSPORIN": 3.7643061213894815, "COBIMETINIB": 35.02899556986354, "CONTRAST": 29.147141242189623, "COSENTYX": 1.4256077190077856, "CYMBALTA": 1.4121786085100956, "HUMALOG": 2.3334183386466307, "IMATINIB": 16.53611659902419, "INLYTA": 15.080731101288189, "JAKAVI": 2.0543411131699485, "LANTUS": 1.1087934789669276, "MEKINIST": 5.901501649971897, "NEXAVAR": 23.754024647137253, "OPTIMARK": 16.368438239246608, "SORAFENIB": 18.3733643542266, "STIVARGA": 21.792225227511054, "SUTENT": 19.395564874249903, "TAFINLAR": 31.339646439611634, "TREMFYA": 4.680934748073876, "VEMURAFENIB": 100.8274759295399, "VOTRIENT": 4.669224456159599, "XELJANZ": 1.4467626409163308, "ZELBORAF": 75.66767677058583, "ZOSTAVAX": 3.8778762548414303}
\ No newline at end of file
+{"COMIRNATY": 0.6687305393910282, "null": 1.205592121999235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3983.json
index 74c121c9dae..97d4d392244 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3983.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3983.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 6.00661033611456, "SIFROL": 57.17855982258489, "STALEVO": 34.69701124488838, "ZYPREXA": 4.524166563001368, "null": 3.485160604075505}
\ No newline at end of file
+{"COMIRNATY": 0.2868410572986537, "KEPPRA": 5.576056915362185, "null": 7.829482673508875}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3984.json
index 175e1e8bbe2..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3984.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3984.json
@@ -1 +1 @@
-{"null": 3.6147353771008457}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3985.json
index d7ec884e0b7..838998eb41c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3985.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3985.json
@@ -1 +1 @@
-{"ABACAVIR": 6.503108083219105, "AMIKACIN": 15.303986672376556, "COAPROVEL": 18.75535041828944, "COMBIVIR": 10.32615128872965, "EFAVIRENZ": 40.39872257930428, "EPIVIR": 45.66328965745541, "IBUPROFEN": 24.53415452523343, "JANUMET": 4.913308736228389, "KALETRA": 18.560511792706837, "KEPPRA": 1.466268083535507, "LAMIVUDINE": 26.679554344313985, "PLAVIX": 1.9215299572350948, "null": 2.3397876309059}
\ No newline at end of file
+{"BORTEZOMIB": 76.38988928367591, "COMIRNATY": 0.4998556314796249, "SPIKEVAX": 0.4841119442804742, "SUTENT": 1.2663199247107213, "VAXZEVRIA": 0.2635408220697959, "null": 0.7753119649055222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3986.json
index 3f834408055..a69846ea5de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3986.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3986.json
@@ -1 +1 @@
-{"FORXIGA": 15.1116064716842, "JANUVIA": 16.563816658372744, "KALETRA": 15.731338313306871, "KEYTRUDA": 3.0402100128312384, "OPDIVO": 10.321826929736323, "TRULICITY": 15.749250667716074, "VICTOZA": 30.11313092837085}
\ No newline at end of file
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3987.json
index bb1ebf8278b..78c81ab4ce1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3987.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3987.json
@@ -1 +1 @@
-{"ABACAVIR": 1.859515225496162, "ABILIFY": 1.13474322817084, "ADCIRCA": 4.939578954714165, "AFINITOR": 4.740089003813893, "ANAKINRA": 2.091261301758052, "ASPARAGINASE": 6.827131841990698, "ATAZANAVIR": 11.282554201473989, "AVANDAMET": 15.304757636588963, "AVANDIA": 10.894237758081053, "AVONEX": 14.811015150856756, "BIKTARVY": 4.419280726988122, "BRILIQUE": 2.004781112576835, "BUSULFAN": 2.853827667827028, "BYDUREON": 4.420872022111512, "BYETTA": 13.93052111593498, "CELLCEPT": 1.7973215707651609, "CIALIS": 4.889486707741651, "CICLOSPORIN": 1.7975604361158712, "COMBIVIR": 4.525457452996397, "CRIXIVAN": 13.585619849108884, "CYTARABINE": 2.0138679805726807, "DARUNAVIR": 17.054909820445843, "EDURANT": 29.80580741826289, "EFAVIRENZ": 12.836098631899391, "EMPAGLIFLOZIN": 3.780612691865135, "ENTRESTO": 1.144364157147408, "EPIVIR": 2.963032159665238, "EXFORGE": 2.433001099534673, "FASLODEX": 1.6309510375366325, "HUMALOG": 1.1316605663773252, "ICLUSIG": 2.1600304147834417, "INDINAVIR": 33.96573037562357, "INSULIN": 1.4388400915461783, "ISENTRESS": 2.985642116493356, "JANUMET": 15.579623058804511, "JANUVIA": 11.766845045807733, "KALETRA": 4.686706307940899, "LYRICA": 2.6633295416151253, "NOT": 3.158938388842871, "OLANZAPINE": 2.745891013859869, "ONCASPAR": 7.555458285586069, "ONGLYZA": 5.668924786666238, "PLAVIX": 1.3906715977176003, "RAPAMUNE": 4.326524495775605, "RINVOQ": 1.6066436295487465, "ROACTEMRA": 1.80921877492062, "TASIGNA": 7.029087789173481, "TIVICAY": 6.78991836222758, "TORISEL": 4.02508443267051, "VIAGRA": 1.1896295972255255, "ZOSTAVAX": 29.05772636951609, "ZYPREXA": 16.807143223473794}
\ No newline at end of file
+{"COMIRNATY": 0.4417481871632261, "GARDASIL": 72.2150223153652, "null": 0.493927577808986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3988.json
index 1972205c6e3..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3988.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3988.json
@@ -1 +1 @@
-{"null": 6.187028974283551}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3989.json
index 830bd68c6ce..a6335089068 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3989.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3989.json
@@ -1 +1 @@
-{"GARDASIL": 3.968422311759035, "HUMALOG": 2.9411069982300866, "OZEMPIC": 234.43314997616017, "ZOSTAVAX": 22.84129668947689, "null": 1.9998058522852}
\ No newline at end of file
+{"BRINTELLIX": 35.3867920741629, "UROREC": 278.87763042882534, "VIAGRA": 26.15578811039196, "null": 3.0582094554056054}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/399.json
index 7e7141e0cb2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/399.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/399.json
@@ -1 +1 @@
-{"null": 2.7785219446407257}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3990.json
index 4a7587be410..befbe38e7a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3990.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3990.json
@@ -1 +1 @@
-{"ARAVA": 6.647557261094192, "CYMBALTA": 4.413393917948008, "GARDASIL": 34.5737603775742, "null": 1.6500287507243918}
\ No newline at end of file
+{"BRINTELLIX": 4.486697194849922, "COMIRNATY": 0.0312451571686831, "CYMBALTA": 2.346156567612913, "SILODOSIN": 429.8428525703207, "SILODYX": 137.4318489637387, "UROREC": 182.75982508068552, "VIAGRA": 179.48332459765524, "ZYPREXA": 1.6958791536928204, "null": 3.394176602402665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3991.json
index 2195d0e7700..25c39a7ee6c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3991.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3991.json
@@ -1 +1 @@
-{"TEMOZOLOMIDE": 3989.270212284088}
\ No newline at end of file
+{"BRINTELLIX": 5.541015208402039, "SILODOSIN": 286.1101086178015, "SILODYX": 726.424772227731, "UROREC": 1366.275005441801, "VIAGRA": 44.64907448214492, "null": 3.938305510329374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3992.json
index badc9636d42..afc87a638f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3992.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3992.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 2.90542864341034, "BRINTELLIX": 2.136542175621704, "BUMETANIDE": 19.02080233809311, "CYTARABINE": 1.6975240476337696, "DEXAMETHASONE": 1.190431994967747, "FENTANYL": 1.4548805786889385, "FORXIGA": 11.670001466419324, "JARDIANCE": 8.935954615055323, "KEPPRA": 1.544002007106259, "LEVETIRACETAM": 3.493030303050896, "LEVOFLOXACIN": 1.6525236675648884, "OLANZAPINE": 6.286318490075148, "PANTOPRAZOLE": 6.213643666350265, "PRADAXA": 15.817071719979564, "SAMSCA": 314.1517471146926, "TOLVAPTAN": 175.80328272586783, "ZYPREXA": 3.954822764883928, "null": 2.8485310982203207}
\ No newline at end of file
+{"APIXABAN": 983.4975124423144, "ELIQUIS": 3.9671450889926287, "ENTRESTO": 6.896740868282619, "ESOMEPRAZOLE": 15.69424139496607, "null": 0.1796552103052057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3993.json
index d7f747c378c..214207d4634 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3993.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3993.json
@@ -1 +1 @@
-{"GLIBENCLAMIDE": 292.1432991117906, "ZYPREXA": 25.421020597272967, "null": 1.403941172460353}
\ No newline at end of file
+{"APIXABAN": 227.68796117011195, "ARIPIPRAZOLE": 7.307954567681184, "BUMETANIDE": 37.77797055980027, "DASATINIB": 63.224074895130514, "ELIQUIS": 6.500460147147728, "ENTRESTO": 35.7475720262455, "HERCEPTIN": 12.262746213510905, "MEKINIST": 7.849323766583291, "SUTENT": 0.9717807973624372, "null": 0.3455212422220189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3994.json
index 22cbf15187e..7b629fa121d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3994.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3994.json
@@ -1 +1 @@
-{"null": 2.441393592880345}
\ No newline at end of file
+{"AFINITOR": 3.0704517580104542, "ALIMTA": 1.122412613457562, "APIXABAN": 2.317857451108242, "ARIPIPRAZOLE": 1.816824396491818, "ASPARAGINASE": 2.19611041313432, "AVANDIA": 2.3196035920313878, "AVASTIN": 4.028470912312301, "AZACITIDINE": 2.48437801264004, "BEVACIZUMAB": 2.3406295322678123, "BINOCRIT": 14.655123957676537, "BONVIVA": 6.229906672438436, "BRAFTOVI": 4.425536664978186, "BRILIQUE": 3.4224705899003265, "BUMETANIDE": 7.202621769364409, "BUSILVEX": 16.800757351779417, "BUSULFAN": 0.9741983021398668, "CABOMETYX": 1.6165814573479187, "CAELYX": 5.790505029138122, "CAPECITABINE": 4.295712838438716, "CARFILZOMIB": 4.877940809146613, "CELLCEPT": 1.2651812251491503, "CICLOSPORIN": 0.6885092374283135, "CLOPIDOGREL": 2.895340246989217, "COBIMETINIB": 10.289766375109766, "COMIRNATY": 0.1272645013604404, "COSENTYX": 0.3906809735186693, "COTELLIC": 14.841143333941892, "CYMBALTA": 0.1843874597167204, "CYTARABINE": 1.3897907960978753, "DABRAFENIB": 28.59351053125258, "DAPAGLIFLOZIN": 12.036689799676948, "DENOSUMAB": 5.64644267530151, "DEXAMETHASONE": 1.0998609301675728, "DOCETAXEL": 19.65072698574972, "DOXORUBICIN": 5.2485025127004175, "EDOXABAN": 31.30861966909152, "ELIQUIS": 0.4635622520379979, "ENTRESTO": 32.600404703756325, "EXFORGE": 0.99897400453201, "EXJADE": 1.758176396635031, "FASLODEX": 1.7156464661089534, "FENTANYL": 1.8166174507471464, "FORXIGA": 0.7352614870539901, "HERCEPTIN": 86.36710166560017, "IBRANCE": 0.2668367383190971, "ICLUSIG": 4.9799410910838615, "INLYTA": 1.828010222619137, "IRBESARTAN": 3.929027789832991, "IRESSA": 1.704728976872328, "IRINOTECAN": 3.600483848459833, "IVABRADINE": 24.22491825993602, "JAKAVI": 0.9483819707427658, "JARDIANCE": 0.5791479743051974, "KEYTRUDA": 1.087958570935851, "KYPROLIS": 16.78775303233424, "LANTUS": 0.3784154790646298, "LENVIMA": 4.071966007755188, "MABTHERA": 3.183457138654644, "MEKINIST": 20.19375858093819, "METHOTREXATE": 0.6339055406288607, "MIDAZOLAM": 1.4941554307447908, "MULTAQ": 8.172417815673962, "NEXAVAR": 1.9008754744598664, "OLANZAPINE": 1.0336286099263627, "PACLITAXEL": 12.104541462081706, "PANTOPRAZOLE": 3.983109801983315, "PERJETA": 18.93911789607467, "PERTUZUMAB": 75.59941775510055, "PLAVIX": 0.3383732760594304, "RITUXIMAB": 2.034809775509157, "SOLIRIS": 0.6465038989919459, "SPIKEVAX": 0.1381717449936989, "SPRYCEL": 0.8750902424650429, "STIVARGA": 0.8648160314611976, "SUTENT": 4.431792451805119, "TAGRISSO": 11.295137675058209, "TASIGNA": 1.224304368579469, "TOZINAMERAN": 0.2255973784945779, "TRAMETINIB": 25.74398628167961, "TRASTUZUMAB": 48.92501618829007, "VALSARTAN": 25.86129382237018, "VAXZEVRIA": 0.0256435225577313, "VOTRIENT": 9.94933144988663, "VYXEOS": 28.066634161035328, "XOLAIR": 0.9523413035708485, "ZYPREXA": 0.33355890261188, "null": 0.9446006145444684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3995.json
index 123465d133c..bf20051849d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3995.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3995.json
@@ -1 +1 @@
-{"ARANESP": 14.1125932972008, "ATRIPLA": 3.728920468137089, "CELLCEPT": 7.7063217209016415, "FORSTEO": 5.065236133670494, "MIMPARA": 27.879968664447784, "PEGASYS": 6.265516394401678, "TRUVADA": 4.462040415720573, "ZOSTAVAX": 3.629773562872243, "null": 1.8804087055467928}
\ No newline at end of file
+{"SPIKEVAX": 33.24078679367958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3996.json
index 38f6fe14014..038fb288ca5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3996.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3996.json
@@ -1 +1 @@
-{"null": 2.955484858645617}
\ No newline at end of file
+{"null": 5.875074040710963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3997.json
index 92da402ef3a..9bc92783913 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3997.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3997.json
@@ -1 +1 @@
-{"ANAKINRA": 59.985525982592, "ARANESP": 13.352019944588278, "ATRIPLA": 12.726096951404992, "TRUVADA": 12.64441609693646}
\ No newline at end of file
+{"ARAVA": 9.311106814813485, "AZATHIOPRINE": 102.8854562245267, "ENBREL": 55.1817012853659, "null": 0.3430315413563459}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3998.json
index 0f4110dc8f0..26b8e8ac8f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3998.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3998.json
@@ -1 +1 @@
-{"ABACAVIR": 3.801172835424252, "ABILIFY": 5.832356104265439, "APIDRA": 6.448577327692834, "ARIPIPRAZOLE": 8.616134703795868, "BIKTARVY": 9.106304444674963, "CHAMPIX": 3.619060167909501, "CYMBALTA": 2.895506825093451, "HUMIRA": 16.399832867299157, "OLANZAPINE": 7.081396549179476, "SIFROL": 20.000566725393885, "ZYPREXA": 23.176904236376306, "null": 1.3068347552539827}
\ No newline at end of file
+{"ARAVA": 6.080807169804451, "null": 0.7840096321632034}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3999.json
index a78f40c8790..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3999.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/3999.json
@@ -1 +1 @@
-{"ARANESP": 323.6734064920491, "ATRIPLA": 1.0090287513548672, "BLINATUMOMAB": 211.95152612027783, "FORXIGA": 4.91337582311263, "MELATONIN": 32.79299335480949, "MIMPARA": 21.13003939953836, "TRUVADA": 2.016318942228509}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4.json
index 7d7d98eb460..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4.json
@@ -1 +1 @@
-{"COMIRNATY": 1.242623628342738}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/40.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/40.json
index 27d572adcc5..2316439461b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/40.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/40.json
@@ -1 +1 @@
-{"ABILIFY": 3.6563687570220855, "ARIPIPRAZOLE": 3.2338208339504115, "BIKTARVY": 13.905583323339515, "BRINTELLIX": 3.649637442603828, "DESLORATADINE": 44.96482191199119, "FORSTEO": 3.4480330966570056, "GENVOYA": 42.45953955944619, "INVEGA": 36.4521364922043, "KEPPRA": 1.1688635805444731, "OLANZAPINE": 11.246950159165372, "RINVOQ": 6.005971472584468, "ZYPREXA": 8.664802590360368, "null": 1.9287958920507289}
\ No newline at end of file
+{"ARAVA": 0.9888622247806385, "COMIRNATY": 0.4265239203549924, "DOCETAXEL": 5.0274011211432885, "FORSTEO": 3.7720066505416714, "JANUVIA": 4.007638307492361, "ROTATEQ": 9.674878005715062, "SPIKEVAX": 0.2576756359244426, "TOZINAMERAN": 0.8322231148573981, "VAXZEVRIA": 0.6566512276811107, "null": 1.4418465476501103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/400.json
index b8ae1b3db27..2df55552166 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/400.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/400.json
@@ -1 +1 @@
-{"CICLOSPORIN": 24.40459777201293}
\ No newline at end of file
+{"NEXAVAR": 17.109712630113386, "null": 0.8022882217487288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4000.json
index 9a86fa8d4d5..0a333d07d66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4000.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4000.json
@@ -1 +1 @@
-{"HEPSERA": 925.0294550685296}
\ No newline at end of file
+{"null": 0.8839493325626656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4001.json
index 8baf3911bcb..11946b4fa6c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4001.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4001.json
@@ -1 +1 @@
-{"TRUVADA": 13.416712855848262}
\ No newline at end of file
+{"COMIRNATY": 0.2434619371974198, "CYMBALTA": 6.524999272462533, "TOZINAMERAN": 1.403479585794217, "VAXZEVRIA": 1.027313360835103, "null": 1.6266582493655528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4002.json
index a1ca1547d24..5bfdb72fa49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4002.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4002.json
@@ -1 +1 @@
-{"ASPARAGINASE": 43.44421060422945, "null": 1.585277929639796}
\ No newline at end of file
+{"ABILIFY": 0.6782208340968424, "AUBAGIO": 2.5672429965761374, "BRINTELLIX": 3.7844405846401417, "BUPIVACAINE": 3.7626801123869886, "CAPECITABINE": 1.6091986655347994, "CHAMPIX": 1.4141818876298542, "COMIRNATY": 0.692672554870522, "CYMBALTA": 77.96541811212425, "DULOXETINE": 3.08516408078946, "FAMPYRA": 2.326474101333175, "GARDASIL": 0.8712553304658585, "LYRICA": 1.1235890680134453, "SHINGRIX": 1.1982625392590949, "SPIKEVAX": 0.4685806348676604, "TOZINAMERAN": 1.4495750098256228, "VAXZEVRIA": 0.4134129555732881, "XELJANZ": 0.2954975917142812, "ZYPREXA": 0.3976819298299107, "null": 1.230629359647601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4003.json
index dcfc16596bd..f840d75d3d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4003.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4003.json
@@ -1 +1 @@
-{"ADCIRCA": 3312.9141942980823}
\ No newline at end of file
+{"COMIRNATY": 1.3072068591174248, "SPIKEVAX": 14.763826789662522, "VAXZEVRIA": 0.4065645450494139, "null": 0.1692407849866467}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4004.json
index f705504b71c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4004.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4004.json
@@ -1 +1 @@
-{"ABILIFY": 10.5796509433522, "ARIPIPRAZOLE": 31.138686187810755, "BRINTELLIX": 8.791477009448968, "CYMBALTA": 1.2492448890165302, "INVEGA": 132.46205883078724, "LATUDA": 51.74356191240668, "LURASIDONE": 169.6362941259309, "OLANZAPINE": 39.34228162824216, "RISPERIDONE": 25.00432169848642, "ZYPREXA": 14.304159997413674, "null": 2.648386313802924}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4005.json
index 09a6752c666..3da33f3594a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4005.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4005.json
@@ -1 +1 @@
-{"BEXSERO": 6.059754661276945, "COMIRNATY": 1.171848019997321, "COVID19": 1.4638619647756792, "DABRAFENIB": 4.713689506436015, "DARZALEX": 3.3493200589099232, "FLEBOGAMMA": 1.8408949016088103, "GANCICLOVIR": 2.218929768062478, "GARDASIL": 1.254999182559976, "HALAVEN": 2.8565623223516066, "HERCEPTIN": 1.4690023273015889, "HEXYON": 169.63819112844877, "INFANRIX": 76.74711253996689, "LEVOFLOXACIN": 1.0123011753149105, "MABTHERA": 2.147906795748211, "MEKINIST": 4.269125840476595, "MENVEO": 9.755469328811758, "MMRVAXPRO": 61.9294216501321, "NIMENRIX": 11.590817879324767, "PERJETA": 6.544825074071549, "PLEGRIDY": 1.0381556344962553, "PREVENAR": 9.054315793598729, "PRIVIGEN": 2.0282736378861026, "PROQUAD": 29.4796726585562, "ROTATEQ": 1.6661972508207474, "SPIKEVAX": 1.607304938538351, "TAFINLAR": 16.748828454881412, "VAXZEVRIA": 2.2518243496536856, "YERVOY": 1.7593311277757944}
\ No newline at end of file
+{"FENTANYL": 20.188407328899903, "null": 2.60077961304476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4006.json
index 07937d3c87b..7235cffca44 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4006.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4006.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 5.257311402388835, "CICLOSPORIN": 1.2406700437229228, "COMTAN": 12.61071844826304, "CYMBALTA": 2.518730397239063, "DULOXETINE": 17.43576302141707, "EPIVIR": 12.526994702101018, "FENTANYL": 4.393008914264482, "GARDASIL": 1.9599453491006589, "IBUPROFEN": 6.08559108966874, "KEPPRA": 1.0050906929865655, "LEVETIRACETAM": 3.1893209471104256, "MIDAZOLAM": 3.801511957690943, "NAGLAZYME": 9.1409000221061, "OLANZAPINE": 8.815765780569599, "RISPERIDONE": 22.62011857434509, "ZYPREXA": 1.4294281946415583, "null": 3.889250719444564}
\ No newline at end of file
+{"ZYPREXA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4007.json
index 8a7c11e984b..05c00a433e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4007.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4007.json
@@ -1 +1 @@
-{"COMIRNATY": 5.196563295091902}
\ No newline at end of file
+{"VIMPAT": 51.93661217876928, "null": 2.775737641821546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4008.json
index fd5a017047e..8ab6be093c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4008.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4008.json
@@ -1 +1 @@
-{"ABACAVIR": 6.378976133651239, "ABATACEPT": 3.341995080375345, "ABLAVAR": 70.04082379006084, "ACETAMINOPHEN": 5.834682110638103, "ACLASTA": 2.3373591013416632, "ACTRAPID": 1.3985254291491829, "ADALIMUMAB": 2.7348615230126083, "ADVATE": 1.4748189220767445, "AERIUS": 1.821083499202688, "ALL": 2.4495782522228144, "ALLERGY": 11.663667858783253, "ALOXI": 2.270165281457616, "ANGIOX": 1.4334861664404237, "ANTIBIOTICS": 1.2841837805174416, "APREMILAST": 3.161166247713074, "APREPITANT": 8.025801396188982, "ARAVA": 4.387726764830991, "ASPARAGINASE": 2.0417621182635104, "AVAPRITINIB": 17.854230528222327, "AVASTIN": 1.1078191787108709, "AVONEX": 1.0804378542685649, "BAVENCIO": 1.7139164047223905, "BENLYSTA": 1.012409828471362, "BENRALIZUMAB": 1.1535596645152617, "BEVACIZUMAB": 1.016157615495191, "BEXTRA": 1.7708544907618156, "BOTULINUM": 7.832189868211626, "BRIDION": 3.0813726860839408, "BUSILVEX": 1.2527607323223044, "BUVIDAL": 1.0422763223314109, "CAELYX": 4.083071907326811, "CARBIDOPA": 1.6108994298325952, "CELECOXIB": 1.0254533931240832, "CERTOLIZUMAB": 1.9692570507312728, "CHLORHEXIDINE": 9.142758970373198, "CIALIS": 2.733820285584924, "CIMZIA": 4.424120274967708, "COSENTYX": 1.166303421105806, "DARZALEX": 1.3437199531565462, "DESLORATADINE": 1.457067530606786, "DUPIXENT": 1.0793918799698232, "EMEND": 2.7277282475411715, "ENBREL": 2.086711100693696, "EPOETIN": 6.2048405343566255, "ERELZI": 2.1299344066647152, "EVRA": 1.4444188125896726, "EVUSHELD": 1.3391699823973433, "FASENRA": 2.3942412351956426, "FASLODEX": 1.1665122715395628, "FASTURTEC": 5.776898181662395, "FLEBOGAMMA": 3.344426321589622, "FLUCELVAX": 1.5744065402171037, "GAZYVARO": 1.6430535603774774, "GLYCOPYRRONIUM": 2.0262044747623738, "HERCEPTIN": 2.044519844185695, "HIZENTRA": 1.3112405967594214, "HYDROCORTISONE": 1.5593044749915983, "INHIXA": 2.4097060858785486, "INSULATARD": 2.18481960960173, "INSUMAN": 3.874387570730978, "ISOPHANE": 1.4615869585388, "JEVTANA": 1.0555651114104945, "KETOCONAZOLE": 2.6482454269344577, "KIOVIG": 3.9186072475493634, "KUVAN": 1.6385022166815812, "LEVEMIR": 1.4031562773136137, "LEVOFLOXACIN": 1.5746859050322306, "LUMINITY": 10.491812645552178, "MENVEO": 1.0431871516958304, "MIRCERA": 2.0380517525422133, "MIRVASO": 3.3112914639899858, "MIXTARD": 4.453007068751582, "MULTITRACE4": 63.82604062080042, "MYCAMINE": 1.2955977209360383, "NAGLAZYME": 1.2977464533698035, "NEULASTA": 1.864264071037372, "NEVANAC": 1.7245540268036728, "NOVOMIX": 2.1337206904577357, "OBINUTUZUMAB": 1.2970475947809066, "OMALIZUMAB": 1.947545491877473, "ONCASPAR": 22.4520723404827, "OPATANOL": 2.8629856762911507, "ORENCIA": 3.0147967468381345, "PACLITAXEL": 1.0608847773145933, "PANTOPRAZOLE": 1.5675884038854409, "PEGASPARGASE": 3.895219141871332, "PERJETA": 4.506661707713622, "PERTUZUMAB": 1.3086463292309192, "PLEGRIDY": 1.1727146405563826, "PRIVIGEN": 2.934393403044051, "PROTAPHANE": 4.761783734351623, "PROTOPIC": 1.4277438707798915, "QARZIBA": 3.5653160292202, "QUTENZA": 2.39786380055675, "RAPISCAN": 1.2753611855176972, "REMICADE": 1.2901501914875748, "REPAGLINIDE": 1.188193171995553, "RIXATHON": 2.846424826582385, "ROACTEMRA": 2.3153696596273066, "SOMAVERT": 4.052739252482582, "STELARA": 1.1712902522422737, "SUBOXONE": 1.324780187949584, "SUFENTANIL": 2.066344387904365, "TAMIFLU": 1.338372486894496, "TORISEL": 2.250187994703694, "TREMFYA": 1.0511283666130242, "TRIUMEQ": 1.4330116093702925, "TWINRIX": 1.9443667550743025, "VECTIBIX": 1.4861146576643596, "VIRAMUNE": 2.727478208548566, "XIAPEX": 3.46007082119764, "XOLAIR": 3.334261641298798, "XYREM": 1.0620352280212535, "ZARZIO": 1.3553008187822584, "ZIAGEN": 11.9867810876284, "ZONEGRAN": 2.2341482219216244, "ZOSTAVAX": 1.170769204153116, "null": 1.6693297052470637}
\ No newline at end of file
+{"COMIRNATY": 6.24131628239582}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4009.json
index 6ffd29583a9..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4009.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4009.json
@@ -1 +1 @@
-{"FONDAPARINUX": 5041.417620442084, "LEVOFLOXACIN": 16.7442650482528, "MILRINONE": 56617.2757639899, "null": 2.068190904451604}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/401.json
index 411eb991104..9c96316f524 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/401.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/401.json
@@ -1 +1 @@
-{"TOPOTECAN": 1333.8882349122905}
\ No newline at end of file
+{"ATRIPLA": 4.004876510141483, "TRUVADA": 2.169895356110505, "null": 1.0350557199872046}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4010.json
index 9d24bc73778..149c89bde8f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4010.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4010.json
@@ -1 +1 @@
-{"CUBICIN": 35.72259692881654, "KEYTRUDA": 1.769077143886707, "METHOTREXATE": 5.647973478582461, "NUCALA": 5.442411682079951, "PACLITAXEL": 18.198247742025284, "PEGASYS": 1.5133026955010862, "PEGINTRON": 2.632444135533732, "null": 1.6040181560461262}
\ No newline at end of file
+{"null": 0.7258599884531305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4011.json
index 0411907f4b0..72bbc7dded0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4011.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4011.json
@@ -1 +1 @@
-{"ENBREL": 13.945891487517772, "FEBUXOSTAT": 37.9628319273163, "LEVOFLOXACIN": 3.4949224392947262, "SIMPONI": 2.642288719273737, "null": 2.502849739652757}
\ No newline at end of file
+{"CLOPIDOGREL": 23.051464321675937, "null": 0.5269870254387709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4012.json
index 6b1996007c1..5332f05fb0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4012.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4012.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 17.839528543460126, "AZILECT": 213.63336841416935, "CANNABIDIOL": 88.82331307979784, "CARBIDOPA": 95.34058254228134, "ENTACAPONE": 165.4767100254095, "LEVETIRACETAM": 5.959144632861045, "LEVODOPA": 259.0407640781477, "SIFROL": 348.30223798376875, "STALEVO": 88.54307920972444, "null": 1.7542896255249003}
\ No newline at end of file
+{"null": 0.584003753717194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4013.json
index d759f8b19e0..a779db4d9bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4013.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4013.json
@@ -1 +1 @@
-{"ABILIFY": 2.049972688583395, "ARIPIPRAZOLE": 1.6243090351587617, "AUBAGIO": 1.612962256548864, "BELIMUMAB": 26.559866388981927, "BENLYSTA": 1.2819438106908263, "BIKTARVY": 2.0124037593218724, "BRINTELLIX": 2.323936572281208, "BRIVIACT": 4.346983317038889, "BUPRENORPHINE": 1.324095100414748, "CARBIDOPA": 4.347881225584343, "CHAMPIX": 2.329649766128405, "COMIRNATY": 1.0661755151388406, "CYMBALTA": 1.8768864451942815, "ESBRIET": 2.149587151394568, "FAMPYRA": 1.7005195777451454, "FASLODEX": 1.1077601706561722, "FIRDAPSE": 5.087513095724264, "FYCOMPA": 2.383497799806398, "GARDASIL": 4.776761134435052, "HIZENTRA": 1.1621110887937138, "IBRANCE": 2.2185289329387463, "INLYTA": 2.319976162969021, "INVEGA": 6.01207201922781, "IRON": 4.946103305847822, "KEPPRA": 3.1867114239231267, "LATUDA": 2.4351623363602144, "LEVETIRACETAM": 1.3279581376304306, "LYRICA": 2.224067639801236, "MELATONIN": 3.10700474972733, "MIDAZOLAM": 1.2695175118529438, "NIMENRIX": 4.714902671182138, "NORVIR": 1.858568751371239, "OCRELIZUMAB": 10.1666284150812, "OLANZAPINE": 2.29371299075397, "OPSUMIT": 1.0326877546906017, "PEGASYS": 1.8234259375781163, "PEGINTRON": 1.3410431815922088, "ROTATEQ": 1.4430030130070923, "RUBRACA": 2.5809900352431043, "SPIKEVAX": 1.1242155756269088, "SUTENT": 1.856069597491316, "TEDUGLUTIDE": 19.10133681389019, "TOZINAMERAN": 2.322969365888668, "VIMPAT": 1.7974064772270453, "XTANDI": 3.345165253333059, "ZYPADHERA": 6.416259329163188, "ZYPREXA": 3.0484420696777907}
\ No newline at end of file
+{"null": 2.147225067505238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4014.json
index acdce599146..f3e6b3b2d95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4014.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4014.json
@@ -1 +1 @@
-{"ADCIRCA": 136.82930560037616, "EXJADE": 16.70671098723399}
\ No newline at end of file
+{"IRBESARTAN": 97.0310900613415, "null": 2.20954197366508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4015.json
index 370d37945bf..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4015.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4015.json
@@ -1 +1 @@
-{"null": 9.826484057423494}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4016.json
index 4615539d233..1b66ff8470a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4016.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4016.json
@@ -1 +1 @@
-{"ABACAVIR": 5.58638880782433, "ABATACEPT": 1.260646873457301, "ABILIFY": 2.605814546966234, "ACE": 1.7909701159656135, "ACLIDINIUM": 2.0391543636049145, "ADALIMUMAB": 1.43672371102903, "AFINITOR": 1.2132977119031658, "AFLIBERCEPT": 4.510027954330581, "AIMOVIG": 1.1957051701954498, "AJOVY": 2.7938050323032027, "ALENDRONATE": 5.087445337647465, "ALISKIREN": 3.5478962905442, "ANTIHYPERTENSIVES": 4.718602907149649, "APIXABAN": 3.948890184146317, "APROVEL": 3.3281757768879405, "ARAVA": 1.168615385072295, "ARIPIPRAZOLE": 1.6433885024013482, "AUBAGIO": 1.785451298104327, "AVANDAMET": 2.128176983403482, "AVANDIA": 1.5803177588451058, "AVASTIN": 3.5082801243620265, "AVELUMAB": 6.896219057994264, "AXITINIB": 8.907816677691093, "BAVENCIO": 7.225008610698339, "BETMIGA": 6.695449284075036, "BEVACIZUMAB": 4.434333862466667, "BIKTARVY": 1.0712023854608144, "BOSULIF": 1.0242224265202895, "BOSUTINIB": 2.020873524020596, "BYDUREON": 1.0642052526336796, "BYETTA": 1.4565178786639703, "CABOMETYX": 5.984146803096716, "CAELYX": 1.1303584214476097, "CANNABIDIOL": 1.0924156464416177, "CAPRELSA": 3.246513604072756, "CARFILZOMIB": 1.012664394765332, "CELECOXIB": 1.1232626108657346, "CIALIS": 1.3550682061607169, "CICLOSPORIN": 2.266685107846941, "COAPROVEL": 2.336777747933982, "COMPRESSION": 8.4274635963524, "CYMBALTA": 1.0354171146216231, "CYRAMZA": 2.5248762972605103, "DAPAGLIFLOZIN": 1.4058824951573767, "DARZALEX": 1.6170273686107917, "DENOSUMAB": 1.1019143357694725, "DEXMEDETOMIDINE": 1.522884511940643, "DINUTUXIMAB": 2.238422995590371, "DUAKLIR": 4.13775575335253, "DULOXETINE": 1.0846026876678545, "ENBREL": 1.6471515687153004, "ENTRESTO": 1.1356335580729608, "ENZALUTAMIDE": 1.4975581086865335, "EPOETIN": 1.3423057013590023, "ERENUMAB": 1.0587025432170123, "ERLEADA": 2.608399803391388, "EVEROLIMUS": 1.2564474323943218, "EXELON": 1.0121697804980132, "EXFORGE": 5.7942242588487405, "FLEBOGAMMA": 7.321868578646285, "FORSTEO": 1.164810248631052, "FOTIVDA": 5.738788442464368, "GALVUS": 2.0966598540794985, "GAVRETO": 2.4760055626867725, "GAZYVARO": 1.034291518219926, "HERCEPTIN": 1.0373958646579666, "HUMALOG": 1.0614700790148546, "HUMIRA": 1.1822113221165682, "HYDROCHLOROTHIAZIDE": 1.7099627820757384, "HYDROCORTISONE": 1.645482455395061, "ICLUSIG": 4.439337080160114, "ILARIS": 4.2768633408657735, "IMBRUVICA": 1.206435956798478, "INLYTA": 7.93588981525814, "INTELENCE": 1.6805631863406525, "IRBESARTAN": 2.0954956251313868, "IRINOTECAN": 1.0861851886459326, "ISOPHANE": 1.3457801813611974, "JANUMET": 2.066679366161157, "JANUVIA": 1.794931529300783, "KARVEA": 2.3184099723719807, "KEYTRUDA": 3.8392457430556126, "KIOVIG": 2.829039417747619, "KYPROLIS": 4.5968470327037, "LEFLUNOMIDE": 1.4362739943661913, "LENVATINIB": 4.255357620400849, "LENVIMA": 13.802416264708938, "LUPKYNIS": 11.374951146910236, "LUTETIUM": 1.771969257370388, "METHOTREXATE": 1.2379339989680858, "MICARDIS": 2.3738624981221395, "MICARDISPLUS": 1.966616759710592, "MIMPARA": 1.1233188443365922, "MIRABEGRON": 7.971688112915015, "MIRCERA": 1.3262976236333013, "MISOPROSTOL": 1.3642017739826304, "MVASI": 2.232886592294536, "NAGLAZYME": 1.045051171096121, "NEXAVAR": 4.752470758247491, "NOXAFIL": 1.3082014099863637, "OMALIZUMAB": 1.32010159046712, "OXYBUTYNIN": 1.57689193176364, "PAZOPANIB": 5.495674879670127, "PEMBROLIZUMAB": 1.1682663021330513, "PERJETA": 1.3090009309870765, "PRITOR": 2.591275157070762, "PRIVIGEN": 3.20228563213158, "PROPRANOLOL": 1.3920812841897268, "QARZIBA": 1.910415129394493, "RAPISCAN": 1.0495837032915163, "RASILEZ": 3.4771411470739224, "REBIF": 1.507156010964716, "REBLOZYL": 2.1647440688028614, "REGORAFENIB": 3.246599268796801, "RIXATHON": 1.0259001656328126, "ROSIGLITAZONE": 2.3806036168080547, "SCEMBLIX": 1.949764889781007, "SOLIRIS": 1.5713340098348088, "SORAFENIB": 3.0134384879071807, "STIVARGA": 4.749046293897282, "SUFENTANIL": 1.2116491362170765, "SUNITINIB": 8.780290190764378, "SUTENT": 4.111030098479426, "TEKTURNA": 4.070054403352931, "TELMISARTAN": 1.567278249368638, "TIKOSYN": 1.7945789148646436, "VALSARTAN": 3.947212109297526, "VELTASSA": 1.0206349298188024, "VIAGRA": 1.9353508724451345, "VOTRIENT": 5.059844539222923, "XTANDI": 1.3359809433435543, "XYREM": 2.9746574395676864, "ZALTRAP": 5.39447631711572, "ZEJULA": 1.1100687762245267, "ZOSTAVAX": 2.1217684623846047, "ZYPADHERA": 2.539246086510817, "ZYPREXA": 1.861136610248889}
\ No newline at end of file
+{"ARIPIPRAZOLE": 5.136693708905806, "CELLCEPT": 1.6426474468519376, "FESOTERODINE": 339.64979337597475, "IBUPROFEN": 4.547230693119836, "LACOSAMIDE": 20.45671238813517, "MIDAZOLAM": 7.359511077484759, "OLANZAPINE": 5.405331624887069, "PROPRANOLOL": 26.135827030316797, "SPIRONOLACTONE": 22.59997050775363, "null": 7.240764303905306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4017.json
index 4e909c5b573..d3c2a41b2ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4017.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4017.json
@@ -1 +1 @@
-{"null": 3.0390232848659395}
\ No newline at end of file
+{"null": 5.465911014126284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4018.json
index 66cfa4c5ca2..92851caef7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4018.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4018.json
@@ -1 +1 @@
-{"AVANDIA": 28.971509755519406, "null": 1.008089787236376}
\ No newline at end of file
+{"null": 1.2139608796753705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4019.json
index fe1b5085d2d..fa272527956 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4019.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4019.json
@@ -1 +1 @@
-{"ALISKIREN": 3.1052416624331927, "APROVEL": 5.691605589918321, "AUBAGIO": 1.0547711355537035, "BETMIGA": 14.94899623366564, "BRIDION": 5.793747311306176, "BRILIQUE": 1.240580574031994, "BRINTELLIX": 1.6826787141994424, "COAPROVEL": 8.96606469471373, "COMIRNATY": 1.6086712005931811, "CYMBALTA": 2.5304852945390333, "DARZALEX": 1.7776701243159791, "EXFORGE": 4.593193105475947, "EYLEA": 1.0359480173604982, "FORSTEO": 1.4910364729274934, "FOTIVDA": 15.13123134719624, "HARVONI": 1.5163282800588258, "ICLUSIG": 2.9854202902178293, "INLYTA": 4.1559687576192905, "JANUMET": 1.251756326474828, "KYPROLIS": 7.544241445533405, "LENVIMA": 6.008694766639326, "LIXIANA": 1.7275199937733474, "MICARDIS": 10.890207669079608, "MICARDISPLUS": 13.864332829667823, "MIMPARA": 4.509104610279337, "NEXAVAR": 1.7512371533723716, "PRIVIGEN": 1.7495110769905866, "PROPRANOLOL": 3.60636810340947, "RASILEZ": 10.961562570895266, "ROACTEMRA": 3.481496542311326, "SOLIRIS": 1.752528214594114, "STIVARGA": 1.8283639170819357, "SUTENT": 1.718739987377979, "TELMISARTAN": 5.356696146564699, "VAXZEVRIA": 1.0629398164643484, "VOTRIENT": 4.912660789291862, "null": 1.0878396083545876}
\ No newline at end of file
+{"null": 1.1631995140575229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/402.json
index 55a79e71a7a..f195c1499ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/402.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/402.json
@@ -1 +1 @@
-{"DABRAFENIB": 1006.3657503455536, "MEKINIST": 107.3960896031414}
\ No newline at end of file
+{"ABILIFY": 1.727359744876189, "ARIPIPRAZOLE": 12.247975009462294, "ATAZANAVIR": 6.643004836640713, "BEDAQUILINE": 9.479007261780232, "BENZODIAZEPINE": 22.97173161425185, "BUPRENORPHINE": 25.50019191789911, "CHAMPIX": 3.6238319326479775, "CYMBALTA": 2.207284366606954, "DELAMANID": 25.62701757663471, "KEPPRA": 2.443001347224849, "OLANZAPINE": 1.6666516828708713, "PEGASYS": 0.4932257107660555, "PEGINTRON": 2.522592023484853, "PREGABALIN": 11.496418322789271, "SUBOXONE": 50.48731469270317, "ZYPREXA": 2.897917832979334, "null": 2.7888422308504905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4020.json
index 766c494ab8d..557ac6f0c97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4020.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4020.json
@@ -1 +1 @@
-{"null": 1.0273357366028335}
\ No newline at end of file
+{"ABACAVIR": 0.4122813636992529, "ABILIFY": 3.5148395625709266, "ADENURIC": 1.3863217915440864, "AERIUS": 2.325154226274264, "AGOMELATINE": 7.206060387942967, "AIMOVIG": 0.2388504544146746, "ALOXI": 8.226379892404765, "AMIKACIN": 7.218605522408021, "AMINOSALICYLIC": 20.009553539409172, "ARIPIPRAZOLE": 11.207419825787635, "ARSENIC": 253.63140734918252, "ASENAPINE": 8.588262012059259, "ASPARAGINASE": 0.5144658180867189, "ATAZANAVIR": 1.159532786786485, "ATRIPLA": 0.0190548737719257, "AVANDIA": 0.124970135716666, "BEDAQUILINE": 67.4492889910647, "BENZODIAZEPINE": 4.489106397781578, "BENZODIAZEPINES": 8.43297277301866, "BETMIGA": 1.0588982077311329, "BORTEZOMIB": 0.843858810799481, "BOSULIF": 1.3542539288615263, "BRAFTOVI": 2.27160784387858, "BREXPIPRAZOLE": 9.149609123764314, "BRILIQUE": 0.7894940165878509, "BRINTELLIX": 2.483161604721336, "BUDESONIDE": 0.1615824478187391, "BUPRENORPHINE": 0.7438334282519647, "CANCIDAS": 1.5310261012565636, "CAPRELSA": 42.41802507870104, "CARFILZOMIB": 1.175967290872146, "CHAMPIX": 0.1458935118514963, "CLOPIDOGREL": 0.4148793584474338, "COAPROVEL": 0.6900295110252146, "COBIMETINIB": 3.440272932233699, "COMBIVIR": 0.605834608518607, "COMIRNATY": 0.0116485794765176, "CORTICOSTEROIDS": 6.182824181576268, "COTELLIC": 2.1219654170119924, "CYMBALTA": 0.9460633026529834, "CYTARABINE": 0.6342279017371941, "DASATINIB": 1.6252952488851318, "DELAMANID": 39.073722321132486, "DELTYBA": 64.12384229545944, "DENOSUMAB": 11.24752656752983, "DESLORATADINE": 2.6230803387564854, "DEXAMETHASONE": 0.9933609921392595, "DEXMEDETOMIDINE": 3.3765495905314906, "DOCETAXEL": 0.2466997756656685, "DOFETILIDE": 38.93381479128505, "DULOXETINE": 2.7313299526828025, "ELIQUIS": 0.2334642066967373, "EMTRICITABINE": 1.871069578384328, "ENTRESTO": 0.1853004283890245, "ENZALUTAMIDE": 1.7797769171436295, "ESOMEPRAZOLE": 2.201495558849452, "FASLODEX": 0.482582034504074, "FENTANYL": 0.8543866440887695, "FULVESTRANT": 1.765346097309127, "GENVOYA": 2.024462664843837, "GLIVEC": 1.47807410780375, "HALAVEN": 0.8445853943303343, "HYDROCORTISONE": 0.5862993995267952, "IBRANCE": 0.1383752302432101, "IBUPROFEN": 2.023541868498093, "INVEGA": 4.219308430202351, "IRBESARTAN": 3.7484294569976098, "IRESSA": 1.5693413861358263, "IRON": 3.117020401875258, "IVABRADINE": 14.944706497890229, "JANUVIA": 0.238863109717234, "KALETRA": 6.9592594429688805, "KEPPRA": 1.1014320548950782, "KETOCONAZOLE": 4.789970606935725, "KEYTRUDA": 0.1376942532042398, "KISQALI": 34.01419135788273, "KYPROLIS": 2.5183917968040723, "LACOSAMIDE": 0.8188477212958274, "LAMIVUDINE": 0.8980930074544543, "LANTUS": 0.0913673510986476, "LATUDA": 1.1627746051665728, "LENVIMA": 1.6951884756351867, "LEVETIRACETAM": 1.4302434286670664, "LEVOFLOXACIN": 9.187658257577167, "LOPINAVIR": 19.611447220983536, "LYRICA": 0.7186872199696045, "MEKINIST": 0.5349267399194326, "MELATONIN": 4.018991099445175, "MEMANTINE": 3.4258917463075487, "MIDAZOLAM": 2.3415223503601554, "MIDOSTAURIN": 12.564313883995508, "MIMPARA": 2.017175315794044, "MULTAQ": 9.647649004262677, "NALOXONE": 13.492775247763587, "NEXAVAR": 0.2784463265870644, "NILOTINIB": 9.12100456628418, "NORVIR": 1.0041469800758591, "NOT": 0.9031254635638298, "NOXAFIL": 12.799748002865092, "OLANZAPINE": 7.85681129203919, "OLYSIO": 1.2752300813828392, "OSELTAMIVIR": 3.324427897010496, "OSIMERTINIB": 5.64770763476954, "PANTOPRAZOLE": 1.5753557881663274, "PLAVIX": 0.2507823800632713, "POSACONAZOLE": 3.563099572978805, "PREGABALIN": 1.5536577852128612, "PRETOMANID": 22.08900263208421, "PROPRANOLOL": 3.336031442452793, "RANEXA": 5.54930487941373, "RANOLAZINE": 14.392136698131354, "REMDESIVIR": 2.6503695079183727, "REYATAZ": 3.1487332357555164, "RIBOCICLIB": 19.127989752419097, "RISPERIDONE": 1.5012518839941964, "RYDAPT": 7.2936575098600755, "SCEMBLIX": 10.286915074612551, "SIGNIFOR": 7.4799445025262035, "SIRTURO": 112.0765038457217, "SPIKEVAX": 0.0049157476101543, "SPINRAZA": 0.8596330735048143, "SPIRONOLACTONE": 2.031898119005041, "SPRYCEL": 3.0042365483041027, "SUBOXONE": 0.1535754774542641, "SUNITINIB": 16.8902170475667, "SUTENT": 0.3117088562028138, "SYCREST": 2.6684345088925614, "TACROLIMUS": 3.153313608304094, "TAGRISSO": 14.629520935685772, "TAMIFLU": 0.224654271299939, "TASIGNA": 12.343597638762292, "TIGECYCLINE": 4.693007721334333, "TIKOSYN": 10.489360458467567, "TOVIAZ": 1.1524660205376098, "TOZINAMERAN": 0.0245509998347881, "TRISENOX": 87.4483537985836, "VALSARTAN": 1.6090921649788132, "VANDETANIB": 28.364739606665385, "VAXZEVRIA": 0.0038470119756997, "VEKLURY": 2.247743398163608, "VEMURAFENIB": 10.930756011241996, "VFEND": 4.520858977192903, "VIMPAT": 1.1580642224942528, "VORICONAZOLE": 7.561895174704058, "VORTIOXETINE": 6.587641231327645, "VOTRIENT": 1.3180731943958237, "XALKORI": 7.204074579501508, "XARELTO": 0.5759184127949748, "XEPLION": 6.694905452022044, "XTANDI": 0.6709208842788206, "XYREM": 0.7571297654994545, "ZELBORAF": 6.043463166343853, "ZYPREXA": 4.594499426067631, "null": 2.5193714302981114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4021.json
index e10d93ddf98..07778eb3cee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4021.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4021.json
@@ -1 +1 @@
-{"CICLOSPORIN": 6.986469870744432, "null": 1.977616594017199}
\ No newline at end of file
+{"null": 3.1210219873705856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4022.json
index ac4a3eba244..3b0ed86c868 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4022.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4022.json
@@ -1 +1 @@
-{"AVANDAMET": 27.68616959106914, "AVANDIA": 30.99793316451888, "ELIQUIS": 1.6430570808996603, "ENTRESTO": 12.308155954952712, "FENTANYL": 3.068442710570729, "JANUVIA": 5.2133195902605936, "ONGLYZA": 89.10909366480809, "SUBOXONE": 3.593834878557539, "ZOSTAVAX": 7.463199066449803}
\ No newline at end of file
+{"null": 1.7801097803014172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4023.json
index 299c030c6df..b7a2ebdac24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4023.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4023.json
@@ -1 +1 @@
-{"ATRIPLA": 5.81513219828528, "ZOSTAVAX": 32.10715896348368}
\ No newline at end of file
+{"null": 1.913393433494604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4024.json
index 378ac902172..6177267e642 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4024.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4024.json
@@ -1 +1 @@
-{"ABILIFY": 2.4099568667395035, "ALIMTA": 1.27431617831495, "CANCIDAS": 5.335012905184868, "CELLCEPT": 1.1917823263265732, "CLOPIDOGREL": 1.199467837936003, "COMTAN": 4.482289071198148, "COTELLIC": 4.8817078958393765, "CUBICIN": 3.183789971470352, "DEXDOR": 67.87160182829832, "DEXMEDETOMIDINE": 11.327580015104171, "ENTACAPONE": 7.379196534772826, "FENTANYL": 2.203080097132748, "FLEBOGAMMA": 18.2845897031136, "IBUPROFEN": 1.5598656052193505, "INCIVO": 3.2305144162995467, "KALETRA": 1.3410744684258689, "KIOVIG": 15.947944483501754, "LEMTRADA": 3.8821894342295913, "MEKINIST": 5.235849971520797, "MIDAZOLAM": 6.094639495203747, "MMRVAXPRO": 1.3089253964364609, "NIMENRIX": 2.214580913911386, "OLANZAPINE": 9.635199522821653, "PRIVIGEN": 7.607573797966813, "SPINRAZA": 2.1185299658147625, "STIVARGA": 2.5571918749185523, "ZYPREXA": 3.820736865382058, "null": 2.148161078465519}
\ No newline at end of file
+{"COMIRNATY": 0.1577899605599481, "null": 2.8559641574825627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4025.json
index 4ad8989d6f1..85b931e46fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4025.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4025.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 2.4602311831937564, "DEXMEDETOMIDINE": 106.40464124789246, "FENTANYL": 87.38915253841068, "METHOTREXATE": 4.156609620018274, "MIDAZOLAM": 47.17750809826777, "SUFENTANIL": 133.87630810898844, "ZYPREXA": 3.5785457210063467, "null": 3.1507725390669017}
\ No newline at end of file
+{"BRIDION": 22.264203309918507, "CICLOSPORIN": 2.1128890683888275, "CLOPIDOGREL": 4.5934385588576125, "COMIRNATY": 0.3418425264247848, "FENTANYL": 20.66135641182584, "KEYTRUDA": 1.0946070283022613, "null": 2.9854190015290354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4026.json
index 31ec05f87ff..75f3f591eee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4026.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4026.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 7.394679872864422, "ATEZOLIZUMAB": 8.26289013904903, "AVELUMAB": 17.66081019452021, "AXITINIB": 6.025984053788545, "BAVENCIO": 14.328706484678364, "BETAFERON": 2.6736518743485163, "CABOMETYX": 4.9834473257923735, "CHAMPIX": 1.0480741721209683, "CIRCADIN": 3.9692516583275887, "DABRAFENIB": 2.1316720979895387, "DAPAGLIFLOZIN": 3.0558402557743243, "EMPAGLIFLOZIN": 6.120619846197168, "EPIVIR": 2.349410922065468, "ERLEADA": 1.5633793546824284, "GALVUS": 1.5172109505608724, "GLYCOPYRRONIUM": 3.854256490556567, "ICLUSIG": 1.6307568508552337, "INLYTA": 5.269074920036991, "INTERFERON": 10.791029692140649, "INTRONA": 9.336094731535342, "IPILIMUMAB": 14.384329526311053, "JARDIANCE": 1.7670959447529735, "KEYTRUDA": 16.505104565147377, "LEMTRADA": 30.24331914374539, "LENVIMA": 2.9696860269319623, "LIBTAYO": 7.8545021524085055, "MULTAQ": 6.79952728465395, "NIVOLUMAB": 13.778586527824569, "OPDIVO": 16.879856701432683, "PACLITAXEL": 1.6886992530672418, "PEGASYS": 6.011153763663096, "PEGINTERFERON": 5.790279601059841, "PEGINTRON": 8.831558827005379, "PEMBROLIZUMAB": 7.741051333738926, "PIOGLITAZONE": 57.903364911478015, "PROPRANOLOL": 4.21090021097424, "REBETOL": 7.280634627887451, "RIBAVIRIN": 1.010639533357203, "SPIRONOLACTONE": 1.706614306115249, "STIVARGA": 1.122861857032572, "SUTENT": 2.772412570594056, "TASIGNA": 1.8724751529860024, "VOTRIENT": 1.5123114857446187, "YERVOY": 3.9315876592628114, "null": 1.995646189586218}
\ No newline at end of file
+{"ABACAVIR": 1.8722099021355612, "ARIPIPRAZOLE": 2.22706516485252, "BRIDION": 13.921814803832056, "CLOPIDOGREL": 4.070618798675494, "COMIRNATY": 1.0054396219537671, "ENTRESTO": 3.4663151846904494, "EVEROLIMUS": 24.214403426721475, "FENTANYL": 9.766166539501734, "IBUPROFEN": 6.101544281606271, "MIDAZOLAM": 11.50615877312332, "OLANZAPINE": 1.6836138922722823, "PLAVIX": 1.3035354186595565, "SPIKEVAX": 0.4555610557888861, "TICAGRELOR": 6.6434971709886135, "TOZINAMERAN": 0.4732987431569151, "VAXZEVRIA": 0.0649077799778946, "null": 2.1667004909934726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4027.json
index 832b740596e..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4027.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4027.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 6.1607699512230045, "BUPRENORPHINE": 2.3953211018168417, "COMBIVIR": 3.0766469571252038, "COMTAN": 11.321824416896892, "CYMBALTA": 1.6059628383438318, "EPIVIR": 6.0388137392567, "FENTANYL": 2.2559107192483365, "GARDASIL": 1.6818157838770469, "IBUPROFEN": 3.205743353596611, "INFANRIX": 11.751743295801267, "KEPPRA": 3.344390891354098, "KETOCONAZOLE": 29.58478134540618, "MIDAZOLAM": 8.426245774606347, "MMRVAXPRO": 7.869019385311396, "OCEAN": 158.83610522990733, "OLANZAPINE": 7.773807210478494, "RISPERIDONE": 6.812703460666097, "ZYPREXA": 3.079811398520228, "null": 3.8665451334302094}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4028.json
index d714b08af2c..251c5a2e7b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4028.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4028.json
@@ -1 +1 @@
-{"null": 6.574430879129772}
\ No newline at end of file
+{"COMIRNATY": 0.1216569195300308, "SPIKEVAX": 0.2646042757127961, "null": 2.751853690573544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4029.json
index dd83a02559f..2148e63f658 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4029.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4029.json
@@ -1 +1 @@
-{"ACE": 255.74431146299892, "BETMIGA": 25.58645950238521, "CYMBALTA": 4.834965793068119, "DEXAMETHASONE": 4.910122293747853, "FAMPYRA": 12.448125500454152, "GARDASIL": 3.698041584363723, "MICARDIS": 12.76128493142163, "OXYBUTYNIN": 38.76044063080097, "TOVIAZ": 20.09643440232842, "ZOSTAVAX": 19.950667271697817, "null": 1.1807805897030113}
\ No newline at end of file
+{"null": 2.058334869644988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/403.json
index 9d5a5c83e01..4a864d3313b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/403.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/403.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 79.46785122459488}
\ No newline at end of file
+{"null": 0.7056531463719815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4030.json
index 285643f12a8..0d4f33f246b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4030.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4030.json
@@ -1 +1 @@
-{"AFINITOR": 1.297797403185911, "ALEMTUZUMAB": 4.149325553018896, "ALIMTA": 6.236898858634018, "ASPARAGINASE": 5.421282670953528, "AUBAGIO": 1.6746981597929844, "AVASTIN": 1.830933101981764, "AVELUMAB": 12.68088634569746, "AXITINIB": 12.064396994877864, "AZATHIOPRINE": 1.4413398355977725, "BIKTARVY": 1.4053437527944086, "BUSULFAN": 1.268901589156686, "CABOMETYX": 5.466048482784253, "CAELYX": 2.337656610588982, "CAPECITABINE": 3.922400271374701, "CELLCEPT": 1.2895905419611855, "CICLOSPORIN": 1.5180788332182693, "COTELLIC": 5.8447392057766345, "CUBICIN": 4.715645780029284, "CYTARABINE": 3.7709309891317626, "DEXAMETHASONE": 2.4084965664063818, "DOCETAXEL": 1.0746365491677847, "ESBRIET": 1.2682945406477832, "ESMYA": 11.116753889695987, "EXJADE": 2.778442021269, "EXVIERA": 9.198437606846044, "GAZYVARO": 5.860827136769324, "HALAVEN": 10.720124075044732, "HERCEPTIN": 4.0855247386006255, "IBRANCE": 2.3679751969131835, "IBUPROFEN": 1.2765233424926956, "ICLUSIG": 2.419927285511357, "INLYTA": 4.049740849509499, "IPILIMUMAB": 13.398479899659156, "IRESSA": 6.531480852162676, "IRINOTECAN": 10.544836731464718, "KAFTRIO": 14.810229418133726, "KALETRA": 11.52045380916123, "KEPPRA": 1.6109913585161342, "KEYTRUDA": 2.3286141971596277, "KISQALI": 18.154727766307488, "LEVETIRACETAM": 3.644663696860511, "LEVOFLOXACIN": 1.958192866256575, "LOPINAVIR": 8.017078428876976, "MEKINIST": 1.4084174050644036, "METHOTREXATE": 3.770724786589712, "MULTAQ": 2.3460573106831637, "NEXAVAR": 2.3681407466998494, "NOXAFIL": 9.717181600805674, "NPLATE": 1.5323326654592568, "OFEV": 7.158299680220993, "OLANZAPINE": 1.6128374301018331, "OPDIVO": 2.152801648897868, "PAZOPANIB": 7.294641958004463, "PEMBROLIZUMAB": 9.423320697365924, "PEMETREXED": 6.8597886032104185, "REMDESIVIR": 37.69700841893579, "RIBOCICLIB": 14.751527832335034, "RINVOQ": 1.6086638596698422, "ROACTEMRA": 3.7582705693042735, "RUBRACA": 5.010802015573565, "STIVARGA": 2.8283745600621306, "TAMIFLU": 1.453334342913589, "TEMOZOLOMIDE": 7.499914540658484, "TRABECTEDIN": 61.68296180850008, "TRACLEER": 1.4584528338551783, "TRIUMEQ": 7.174762543246094, "VEKLURY": 53.03210328347535, "VFEND": 1.0668836023578965, "VORICONAZOLE": 6.225721462704013, "VOTRIENT": 8.765312647622824, "XALKORI": 5.77310332854318, "YERVOY": 6.916256578616816, "YESCARTA": 4.145280065610461, "YONDELIS": 26.536317994353084, "ZEPATIER": 11.505857133645623, "null": 1.1717690898098003}
\ No newline at end of file
+{"null": 1.4293166421256611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4031.json
index 877d36d2424..f461cb7f904 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4031.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4031.json
@@ -1 +1 @@
-{"CICLOSPORIN": 17.890695130430036, "null": 4.681538921448591}
\ No newline at end of file
+{"COMIRNATY": 0.0927202552811487, "FENTANYL": 4.754391190949352, "GARDASIL": 6.768431223725661, "null": 2.078631155409554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4032.json
index 15e64d8ad95..26ed8b78e82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4032.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4032.json
@@ -1 +1 @@
-{"ABACAVIR": 5.814932666104827, "ADENURIC": 9.960953698040502, "AFINITOR": 6.691169263402753, "APIDRA": 1.36264459987003, "ASPARAGINASE": 39.53357680926413, "ATAZANAVIR": 6.20822825797017, "AZATHIOPRINE": 2.821445566590874, "BIKTARVY": 2.345542398288093, "BYETTA": 3.46721700548565, "CELLCEPT": 1.1827371708779992, "CICLOSPORIN": 1.431070768527719, "COMBIVIR": 22.572677471226296, "COSENTYX": 2.4572363129928765, "CRIXIVAN": 78.43224785587607, "CYTARABINE": 2.975052763041889, "DEXAMETHASONE": 4.142055566238585, "EFAVIRENZ": 4.035476968333149, "EMTRICITABINE": 8.325414961562897, "EMTRIVA": 19.27069761347895, "EPIVIR": 51.79666303790715, "FASTURTEC": 56.7835595759765, "FORTOVASE": 80.38347635221086, "FORXIGA": 1.3527995938862674, "ICLUSIG": 5.53918065904896, "INCIVO": 3.9926395481990777, "INDINAVIR": 28.139140514324016, "INVIRASE": 119.9334095543476, "ISENTRESS": 5.462641043151266, "JAKAVI": 3.6152049458251634, "JANUVIA": 2.11199929218251, "KALETRA": 57.19613741529389, "LAMIVUDINE": 16.378838925631023, "LOPINAVIR": 11.817173113705076, "LYRICA": 1.004309074043554, "METHOTREXATE": 1.616711168820699, "NEVIRAPINE": 11.968615933076451, "OLANZAPINE": 5.820701599233047, "ONCASPAR": 68.31196412915445, "PEGASPARGASE": 55.46322503486626, "PEGASYS": 1.2196747247388784, "RAPAMUNE": 8.74494750542327, "RINVOQ": 1.948169235125202, "ROACTEMRA": 2.6715366198221475, "STELARA": 1.2885123835328975, "SUTENT": 1.4370462491249771, "TASIGNA": 2.075230482735936, "TEMSIROLIMUS": 37.08302601852363, "TORISEL": 11.689391749696656, "ZOSTAVAX": 1.4166615320575118, "ZYPREXA": 10.606737216144456}
\ No newline at end of file
+{"CUBICIN": 66.05628602373844, "FENTANYL": 16.021632847945728, "null": 2.285476587393144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4033.json
index f86127dfc1f..7158b0bcae3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4033.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4033.json
@@ -1 +1 @@
-{"AVANDIA": 3.912040721943266, "LEVETIRACETAM": 22.06533167375348, "null": 1.5557216638643925}
\ No newline at end of file
+{"null": 3.4003446336207035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4034.json
index af1085e469c..5369a2a553e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4034.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4034.json
@@ -1 +1 @@
-{"VORICONAZOLE": 473.5437946723953}
\ No newline at end of file
+{"BEDAQUILINE": 21.26716683437778, "CLOPIDOGREL": 1.8394143418503817, "COMIRNATY": 0.4599836328991123, "ELIQUIS": 0.7916579008099294, "ENTRESTO": 6.10130576216825, "FENTANYL": 4.41831382375966, "FINGOLIMOD": 419.3855741897945, "OLANZAPINE": 3.3947572251146, "SPIKEVAX": 0.1746759545984611, "VAXZEVRIA": 0.0692379537715839, "null": 2.7098058109639456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4035.json
index 79d92a4fc76..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4035.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4035.json
@@ -1 +1 @@
-{"null": 1.3193243928001126}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4036.json
index dded7c48d9c..b14f63ff6f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4036.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4036.json
@@ -1 +1 @@
-{"null": 1.402234450941821}
\ No newline at end of file
+{"SPIRONOLACTONE": 125.89105712044372, "null": 2.725248263208032}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4037.json
index 3b22a7892f0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4037.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4037.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2996851003312877, "null": 1.3363182569655443}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4038.json
index 2d4b47ca5b2..cf89bd7c884 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4038.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4038.json
@@ -1 +1 @@
-{"BRILIQUE": 8.397172580407103, "CELLCEPT": 8.262234278178871, "CICLOSPORIN": 1.6556685251769565, "COAPROVEL": 11.60637674483948, "COMBIVIR": 5.458660354075048, "DAPAGLIFLOZIN": 52.02265574909392, "ENTRESTO": 1.8340138612387795, "EXFORGE": 3.006942678953681, "FORSTEO": 2.276734074500842, "INCIVO": 14.17020391769327, "IRBESARTAN": 5.005433905653601, "JAKAVI": 3.1074759607783338, "KEYTRUDA": 1.083042437770478, "LEVOFLOXACIN": 1.5237269601693386, "METHOTREXATE": 1.3761666418300973, "MICARDIS": 4.241342658728513, "MICARDISPLUS": 56.98978011291496, "NEXAVAR": 2.3850677568379104, "OLANZAPINE": 3.793125129361596, "PEGASYS": 1.6988007859304124, "PEGINTERFERON": 23.365808676321887, "PEGINTRON": 24.50673824102144, "REBETOL": 12.16986048262845, "SUTENT": 1.6389438688204478, "null": 1.3209488303072705}
\ No newline at end of file
+{"null": 1.9086754803792847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4039.json
index 853d26cb69b..9267f17ed47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4039.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4039.json
@@ -1 +1 @@
-{"BRILIQUE": 2.373989795856883, "CHAMPIX": 2.2273284450188022, "COMIRNATY": 1.4889045183267309, "FASENRA": 1.7994681840456914, "FENTANYL": 1.5510586903466876, "GARDASIL": 10.850281370163048, "HYDROCORTISONE": 3.053036580347279, "IBUPROFEN": 1.267451296732701, "IRON": 6.937358267364627, "JARDIANCE": 3.034740218011644, "LATUDA": 3.0548652769830373, "MIDAZOLAM": 1.9562561384174213, "NIMENRIX": 1.7955847577132846, "OLANZAPINE": 1.006116913829297, "TOZINAMERAN": 1.200963174415586, "TWINRIX": 2.877268554592895, "XOLAIR": 4.153475508116762, "ZYPREXA": 1.244291761214949, "null": 1.4468886873275584}
\ No newline at end of file
+{"null": 6.798293997947634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/404.json
index 353661ff961..cc1c15c79b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/404.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/404.json
@@ -1 +1 @@
-{"STELARA": 35.5262269502468}
\ No newline at end of file
+{"BRINTELLIX": 5.069399028183685, "BUPRENORPHINE": 44.64250852991062, "CHAMPIX": 28.7329509594068, "CYMBALTA": 0.8668086457311278, "VIAGRA": 5.777872679256765, "null": 3.833516398125868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4040.json
index 468276d374c..fd8d777aa2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4040.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4040.json
@@ -1 +1 @@
-{"CYMBALTA": 4.924775097611434, "null": 2.064737156590052}
\ No newline at end of file
+{"ABILIFY": 1.005311001460623, "AIMOVIG": 0.5797933485918881, "APIXABAN": 0.786760201551813, "AVANDIA": 1.4998696401457332, "BRILIQUE": 4.659323552313481, "BYETTA": 0.8829527168363454, "CLOPIDOGREL": 0.4354402067028614, "COMBIVIR": 2.6318488674283325, "COMIRNATY": 0.9109615787817152, "CYTARABINE": 1.3546282338283595, "ENTRESTO": 2.6627722430024354, "EXFORGE": 1.424074923205868, "EXJADE": 0.7597361214913513, "FENTANYL": 4.746380583981456, "IBUPROFEN": 2.079868322699556, "KALETRA": 2.8061185953535777, "KEPPRA": 0.3539761530760839, "LANTUS": 0.3357171927729024, "MIDAZOLAM": 3.971742243899257, "MULTAQ": 3.2559949144933698, "OLANZAPINE": 3.8192751474286486, "PEGINTRON": 0.5495482698315391, "PLAVIX": 0.482395836541205, "SPIKEVAX": 0.702757903710668, "SPIRONOLACTONE": 6.037101156183706, "SUTENT": 0.5877015704471451, "TASIGNA": 1.1749534769848322, "TELMISARTAN": 4.918461170090918, "TOZINAMERAN": 0.902482864251926, "VAXZEVRIA": 0.1205345386843705, "XOLAIR": 0.7762120990611654, "ZOSTAVAX": 1.0608478201871745, "ZYPREXA": 2.3059323158623317, "null": 2.138434865883305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4041.json
index 4b5bfd3842c..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4041.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4041.json
@@ -1 +1 @@
-{"HYDROXOCOBALAMIN": 12004.371426589903, "null": 2.070447818919116}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4042.json
index 744d799ea36..14b9fca22ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4042.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4042.json
@@ -1 +1 @@
-{"null": 2.848173647013041}
\ No newline at end of file
+{"null": 0.7437140097535307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4043.json
index e26c1b633b8..d0d774ae613 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4043.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4043.json
@@ -1 +1 @@
-{"null": 3.018316396517281}
\ No newline at end of file
+{"AVANDIA": 4.942959132239823, "COMIRNATY": 0.1974897123412697, "null": 3.225077748635413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4044.json
index 3d0272f9a78..38b3c0dcf26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4044.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4044.json
@@ -1 +1 @@
-{"ADCIRCA": 21.72081284231022, "ADEMPAS": 17.56384877407431, "ALEMTUZUMAB": 3.215750790250513, "AMBRISENTAN": 17.603873303054794, "ARANESP": 3.3281553747046213, "AVANDIA": 6.426760338457346, "BUMETANIDE": 9.80238224509852, "BYETTA": 1.2672142009571128, "CASPOFUNGIN": 8.447805013972856, "CELLCEPT": 1.5120575844616606, "CICLOSPORIN": 2.10017371773616, "CYTARABINE": 3.5097280343200747, "DARZALEX": 2.6873569924139105, "DASATINIB": 27.36786162335604, "DEXAMETHASONE": 2.9397792575712067, "ENTRESTO": 9.188865675520768, "EXJADE": 3.036101144071559, "FIRDAPSE": 4.827315829800914, "HUMAN": 3.723911452673895, "JANUMET": 1.607725591546925, "JANUVIA": 1.1870763364979269, "KYMRIAH": 8.987968137474015, "KYPROLIS": 5.086940471619675, "MACITENTAN": 22.433644452740907, "MELPHALAN": 12.324453460790409, "NPLATE": 2.727583185079108, "OPSUMIT": 55.13099627130838, "OPTIMARK": 3.722330189238125, "PRIVIGEN": 5.634730193326282, "REVATIO": 9.17370626259317, "SILDENAFIL": 8.36017983770305, "SOLIRIS": 7.358756562480629, "TRACLEER": 27.857632952953256, "VELTASSA": 14.59895076502313, "VOTRIENT": 1.500481497599785, "XARELTO": 3.858669192579097, "YESCARTA": 4.527191962245125, "null": 1.0822080194907944}
\ No newline at end of file
+{"null": 1.2317673923465602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4045.json
index 539fa0bb581..0406311904e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4045.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4045.json
@@ -1 +1 @@
-{"CABAZITAXEL": 377.29541831882256, "CLOPIDOGREL": 13.369445891243243, "EYLEA": 42.69452236190926, "null": 1.308409454450204}
\ No newline at end of file
+{"COMIRNATY": 1.5027937036114756, "SPIKEVAX": 17.256580365617623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4046.json
index 0aa67f457fa..33d191aaa75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4046.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4046.json
@@ -1 +1 @@
-{"null": 1.5720074500984662}
\ No newline at end of file
+{"BUDESONIDE": 6.125364422174823, "COMIRNATY": 0.283593505870436, "null": 2.628448003413599}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4047.json
index bb4687fc726..753882e1508 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4047.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4047.json
@@ -1 +1 @@
-{"DELAMANID": 726.6622874169204}
\ No newline at end of file
+{"null": 0.5545908350269357}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4048.json
index dc16c23526a..e070634475f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4048.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4048.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.4597272850994163, "ADCIRCA": 1.9864406163640285, "ALENDRONATE": 41.49182391592704, "AMBRISENTAN": 2.7916473154467707, "AMIKACIN": 5.5624242736819625, "AMINOSALICYLIC": 1.8383139298648647, "APIDRA": 1.0805788667762977, "APIXABAN": 3.351723965112884, "APROVEL": 1.084624075791698, "BEDAQUILINE": 5.581938523428828, "BOSULIF": 2.228443779484894, "BRAFTOVI": 3.5123686237946736, "BUDESONIDE": 1.6103782626036107, "BUPIVACAINE": 3.160002270525049, "BYDUREON": 1.5585384746009758, "CANAGLIFLOZIN": 27.64660658007411, "ELIQUIS": 2.0059797098908456, "EPIVIR": 1.6726744089272851, "ESBRIET": 1.2036964586351528, "EXFORGE": 1.842814849498983, "EXJADE": 6.995223103479724, "FASENRA": 1.2606419084553342, "GARDASIL": 1.193256629622813, "HALAVEN": 2.378541856073025, "HUMALOG": 4.181570700584396, "HYDROCORTISONE": 3.279165838952511, "IBRANCE": 3.868031664252529, "INLYTA": 1.3782221169213953, "INTRONA": 3.273474989013229, "LANTUS": 3.9067271038355855, "LEVEMIR": 1.934197575764544, "LYRICA": 1.6706410384431625, "MICARDIS": 1.8658097312051405, "NAGLAZYME": 1.4641217513006906, "OPSUMIT": 1.039075788113461, "PEGASYS": 1.1322361680521542, "PEGINTRON": 3.0076588118825054, "RANOLAZINE": 6.349896577988758, "REBETOL": 2.0878264192928864, "REVATIO": 5.719086414861202, "SILDENAFIL": 2.927163252978739, "TELMISARTAN": 1.593303205410146, "THALIDOMIDE": 1.4209818004294958, "TOBRAMYCIN": 5.694307325151266, "TOUJEO": 3.283023781992304, "TOVIAZ": 4.832171904964978, "TOZINAMERAN": 1.117410888952742, "VELTASSA": 1.128767205331807, "VFEND": 1.2689829743099583, "VIAGRA": 9.31538317451052, "XALKORI": 1.2555624134054308, "XELJANZ": 4.139054976746869, "ZOSTAVAX": 1.5975147292656553, "null": 1.236703270540227}
\ No newline at end of file
+{"SPIKEVAX": 3.542602887455461}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4049.json
index fbf31e0c9e4..7c8ed815f85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4049.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4049.json
@@ -1 +1 @@
-{"ABATACEPT": 1.4820260474483746, "ADALIMUMAB": 1.811695970630011, "AIMOVIG": 2.8584624201666777, "APREMILAST": 3.4200725946268364, "AUBAGIO": 4.97711467130966, "AVONEX": 1.5518363660184171, "AZILECT": 1.7263245894783992, "BC": 6.687718745860841, "BETAFERON": 1.528959571401146, "BLINCYTO": 1.7524791020136563, "BUPIVACAINE": 2.6084091254059705, "CANNABIDIOL": 1.4527962773990115, "CERVARIX": 1.278497328376411, "COMIRNATY": 2.276074217052864, "CONTRAST": 1.3991174686672836, "COVID19": 1.5475701570140978, "ETANERCEPT": 1.7189486359250974, "FAMPRIDINE": 1.7411393416796763, "FAMPYRA": 1.013232348588216, "FASLODEX": 1.1662257532914562, "FIRDAPSE": 1.6732143188187814, "FLUCELVAX": 1.1181264091706846, "GARDASIL": 2.8673290603280543, "INTELENCE": 1.0582089966080408, "IXIARO": 3.163511475907124, "KESIMPTA": 2.9636502819010446, "LEMTRADA": 1.2476046855032443, "LOPINAVIR": 1.0716062479606594, "LYRICA": 1.4425109822738016, "MAYZENT": 7.042494970994402, "NEUPRO": 1.8709780051477272, "OCEAN": 6.216929041966256, "OCRELIZUMAB": 2.9323980622877683, "OPTIMARK": 7.065726247848556, "ORENCIA": 1.4365862954019704, "PLEGRIDY": 1.1527002995117812, "PRIALT": 1.5026907954539692, "REBIF": 2.05482522144224, "SEEBRI": 3.45494405934379, "SHINGRIX": 1.3663000091340336, "SIRTURO": 1.195309336097396, "SPIKEVAX": 1.337922124149062, "SUFENTANIL": 1.2403090312217842, "TECFIDERA": 1.5740897798639482, "TEKTURNA": 1.9251883231345224, "TERIFLUNOMIDE": 3.1773718405128504, "THALIDOMIDE": 1.143664574042032, "TOZINAMERAN": 2.5408558399282644, "TWINRIX": 2.694438347115633, "VAXZEVRIA": 1.4428555214743817, "XELODA": 1.887211567962784, "ZERIT": 2.252591092118696, "ZEVALIN": 3.727758363392819}
\ No newline at end of file
+{"ASPARAGINASE": 13.85665644314401, "CICLOSPORIN": 2.803795554687909, "COMBIVIR": 11.393316842986644, "COMIRNATY": 0.0582279169301778, "CYMBALTA": 0.9014988610225044, "FENTANYL": 4.990908801818381, "GARDASIL": 1.4752046344256566, "HYDROCORTISONE": 4.368647346545763, "KEPPRA": 7.725110651124828, "LEVETIRACETAM": 20.781853516182707, "MIDAZOLAM": 16.371675420703603, "OLANZAPINE": 4.942991346860855, "SODIUM": 87.68644476337025, "VIMPAT": 9.860301414622144, "ZYPREXA": 5.525788423732841, "null": 3.145510070428294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/405.json
index 81df261923c..bb56f9afbee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/405.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/405.json
@@ -1 +1 @@
-{"null": 1.321596290799513}
\ No newline at end of file
+{"CHAMPIX": 13.012596496332264, "COMIRNATY": 0.510272960799927, "GARDASIL": 3.997143694867675, "SPIKEVAX": 0.4968235401095703, "TOZINAMERAN": 0.8373139330425579, "VAXZEVRIA": 0.3433968962579011, "null": 2.37731060023918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4050.json
index 0a33e345a1b..4e6443db2c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4050.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4050.json
@@ -1 +1 @@
-{"ABILIFY": 197.26203943944765, "COMIRNATY": 1.0955134567269191, "TOZINAMERAN": 3.3728637076412324}
\ No newline at end of file
+{"AMINOSALICYLIC": 34.006751629964945, "null": 1.0945039906191687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4051.json
index 1ca208c2ef1..5f739390af3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4051.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4051.json
@@ -1 +1 @@
-{"AIMOVIG": 1.2211474323836535, "COMIRNATY": 2.074327469183596, "COVID19": 1.235949060653461, "DELTYBA": 18.55018265650824, "EVENITY": 1.300348825692058, "FENTANYL": 1.3589973720660202, "FIRDAPSE": 12.427589323305709, "SPIKEVAX": 1.098020753458657, "SYCREST": 22.59341818626025, "TOVIAZ": 1.3406592024032302, "TOZINAMERAN": 3.30126526007234, "VAXZEVRIA": 1.0839764561695369, "VIMPAT": 1.0440186607377375, "XOLAIR": 1.0598316502970544, "null": 1.2422287862510033}
\ No newline at end of file
+{"AFINITOR": 1.427486510747605, "ALISKIREN": 4.595658487868896, "AMIKACIN": 6.020200806806434, "AMINOSALICYLIC": 6.448536023567732, "ASPARAGINASE": 1.575984880477994, "AVASTIN": 1.13584009196156, "BEDAQUILINE": 13.418130212401026, "BENZODIAZEPINES": 39.838417985701255, "BEVACIZUMAB": 1.3750636417068558, "CAPECITABINE": 5.045204901556288, "CELLCEPT": 0.9831790461403076, "CICLOSPORIN": 1.9778874644211373, "CLOPIDOGREL": 1.141708143690439, "COAPROVEL": 5.66118340361966, "COMIRNATY": 0.0484523162907631, "CYMBALTA": 0.5186151923938381, "CYTARABINE": 1.8358826478377108, "DELAMANID": 12.277859677625385, "DEXAMETHASONE": 1.374123076616277, "DEXMEDETOMIDINE": 19.769814507836617, "DOCETAXEL": 1.4760291705316742, "DULOXETINE": 5.1646976191580976, "ENTRESTO": 1.316661417274162, "EVEROLIMUS": 6.312003765456354, "EXJADE": 1.4796146361236922, "GARDASIL": 0.4263184716266524, "IBRANCE": 0.4668274488834014, "IBUPROFEN": 1.2025909756135558, "IRBESARTAN": 3.688027549686892, "JANUMET": 1.2555001999218685, "JANUVIA": 1.5450886050673804, "JARDIANCE": 2.018033165205887, "KALETRA": 2.969301936316937, "KEPPRA": 0.3968367890011338, "KEYTRUDA": 2.2884304236310617, "KYMRIAH": 2.997902569153828, "LANTUS": 0.2999816754970952, "LENVIMA": 2.8846279584939047, "LEVETIRACETAM": 2.140458865779392, "LEVOFLOXACIN": 1.5366118066557446, "LYRICA": 1.060088641668649, "MEKINIST": 2.3667273641171405, "MICARDISPLUS": 16.370008908521847, "NEULASTA": 1.677987643546457, "NEXAVAR": 1.5273822812396285, "OLANZAPINE": 0.8190087620648134, "OPDIVO": 0.9795840803413622, "OPSUMIT": 1.1246135398963066, "PANTOPRAZOLE": 5.1105855358702295, "PEGASYS": 0.7303218293589221, "PEGINTRON": 0.8446164179857023, "PLAVIX": 0.4267890751150426, "SOLIRIS": 0.9123715705470632, "SOMATROPIN": 9.670530122271732, "SPIKEVAX": 0.059211849831791, "SPIRONOLACTONE": 4.820860539541292, "SUTENT": 1.195039224553366, "SYNAGIS": 2.367566494330382, "TACROLIMUS": 11.05953188385152, "TOZINAMERAN": 0.0636134361968761, "TRULICITY": 1.3405869173836529, "VAXZEVRIA": 0.0385590650344713, "VORICONAZOLE": 3.933001171890683, "VOTRIENT": 2.1646289537605106, "XYREM": 7.033362324740189, "ZYPREXA": 1.6924456936315118, "null": 1.9251163389518604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4052.json
index 955e5aef576..f3d9ac3b98a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4052.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4052.json
@@ -1 +1 @@
-{"AFINITOR": 1.5178755199745415, "ALIMTA": 3.3909226247658046, "AMIKACIN": 6.738321961176094, "AMINOSALICYLIC": 11.426984510850284, "ASPARAGINASE": 6.487132446655406, "AVASTIN": 3.626102605887076, "BEDAQUILINE": 5.222747348415804, "BEVACIZUMAB": 3.7346876644465583, "BUDESONIDE": 1.5460782569054197, "CABOMETYX": 4.693687742726391, "CAPECITABINE": 3.0858001529035177, "CASPOFUNGIN": 15.573376294223124, "CICLOSPORIN": 6.625031317786491, "CLADRIBINE": 16.954039956950083, "CYTARABINE": 5.501123724480826, "DELAMANID": 11.386066880600126, "DOCETAXEL": 3.427118686237361, "ERBITUX": 12.462634104754642, "FILGRASTIM": 10.094315017292956, "IBUPROFEN": 3.128634439856203, "INTRONA": 7.149185188044743, "KEYTRUDA": 3.170103430007354, "LAMIVUDINE": 11.400843057685156, "LENVIMA": 4.647739014787701, "LEVETIRACETAM": 1.2772926939431404, "METHOTREXATE": 1.302033475305561, "NEXAVAR": 4.714868488078781, "OLANZAPINE": 2.238354369643893, "ONCASPAR": 22.7291142734394, "OPDIVO": 1.5781044481471196, "PEGINTERFERON": 1.998213553158838, "PEGINTRON": 2.078539569897931, "RITUXIMAB": 4.177717973622568, "STIVARGA": 5.612907304162706, "SUTENT": 2.456992256620264, "VFEND": 1.6655247935751831, "VOTRIENT": 2.4101799509869903, "YESCARTA": 21.912588334117206, "null": 1.047762348299688}
\ No newline at end of file
+{"null": 1.7303640841198316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4053.json
index c6a95af27f7..399caf8ec21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4053.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4053.json
@@ -1 +1 @@
-{"null": 1.0029216615858632}
\ No newline at end of file
+{"null": 0.759305963222717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4054.json
index 71709a2e643..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4054.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4054.json
@@ -1 +1 @@
-{"null": 1.2247091705287942}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4055.json
index ec59cc2962b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4055.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4055.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.44490351741787, "AERIUS": 3.032559941017974, "AFINITOR": 1.5212782361052029, "ALIMTA": 2.173852545930351, "AMINOSALICYLIC": 9.439833480371767, "ANAKINRA": 1.595141083048068, "ARANESP": 1.217896843913454, "AVASTIN": 1.4521221130553297, "BEDAQUILINE": 5.7005565431640655, "BEVACIZUMAB": 1.9080385354388785, "BONVIVA": 9.375353809534593, "BORTEZOMIB": 3.996073076073188, "CABOMETYX": 6.104643418078428, "CAPRELSA": 13.812540258386909, "CELLCEPT": 1.7330153147996137, "CINACALCET": 116.03859378297116, "COMBIVIR": 3.449456698593633, "DARZALEX": 1.9583293227073768, "DELAMANID": 7.928129374143202, "DENOSUMAB": 14.78450658727745, "DEXAMETHASONE": 2.595050792624215, "DOCETAXEL": 2.87736709661984, "DULOXETINE": 2.8516948771703485, "ERBITUX": 15.833808627480296, "ESOMEPRAZOLE": 4.315871481939196, "EVENITY": 20.622950207417933, "FENTANYL": 1.7628169266944227, "FILGRASTIM": 3.3445146855594885, "FORSTEO": 1.6067589621028535, "HYDROCORTISONE": 2.3939519173738706, "JEVTANA": 3.3145491172610684, "KALETRA": 1.2272497342922553, "KEYTRUDA": 1.8426054964896883, "KISQALI": 2.4715232658730213, "LENVIMA": 3.827131628437941, "LEVETIRACETAM": 1.2845358935823366, "LEVOFLOXACIN": 1.6190647627908965, "LOXAPINE": 28.709133522073564, "METHOTREXATE": 1.653848864936466, "MIDAZOLAM": 1.9436979998760648, "MIMPARA": 164.03636205488937, "NATPAR": 270.811839485896, "NEXAVAR": 4.161016356003176, "OLANZAPINE": 2.199427413226372, "PANTOPRAZOLE": 7.256601334272997, "PEGINTERFERON": 1.2946418703067963, "PEMBROLIZUMAB": 1.801917491929608, "PROLIA": 44.18413924393011, "REVATIO": 1.9857708746728877, "RIBAVIRIN": 7.493382316681053, "SORAFENIB": 9.6470695970997, "STIVARGA": 3.3513129373358432, "SUTENT": 1.2449085485997446, "VECTIBIX": 8.870293595804027, "VILDAGLIPTIN": 20.615279119395343, "VIREAD": 2.323657612204268, "XGEVA": 45.58729986690024, "ZOLEDRONIC": 65.58578364951654, "ZOMETA": 19.713913298984803, "null": 1.6505125628237831}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4056.json
index 03b778baaf1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4056.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4056.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4057.json
index 6ce5cd6a6a1..86076c620a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4057.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4057.json
@@ -1 +1 @@
-{"null": 5.39741127910699}
\ No newline at end of file
+{"DULOXETINE": 956.4384185854618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4058.json
index 98ff72f3411..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4058.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4058.json
@@ -1 +1 @@
-{"null": 2.196982643309022}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4059.json
index 4641590c7e0..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4059.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4059.json
@@ -1 +1 @@
-{"null": 8.009118968725161}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/406.json
index 5e17a3bead2..0929f8c227b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/406.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/406.json
@@ -1 +1 @@
-{"null": 4.114099390788256}
\ No newline at end of file
+{"AMINOSALICYLIC": 5.001489980624515, "BEDAQUILINE": 16.803271022461573, "BUPRENORPHINE": 5.013936766491466, "BUVIDAL": 65.59706160161677, "CHAMPIX": 6.930295939797584, "COMIRNATY": 0.0799689805561458, "CYMBALTA": 2.5053787351847827, "DELAMANID": 54.9834279945252, "FENTANYL": 9.244850216422348, "IBUPROFEN": 3.729612664217967, "KEPPRA": 1.5256990726444868, "PREGABALIN": 19.271824525503582, "SUBOXONE": 2.7883742421276456, "ZYPREXA": 4.09410588870549, "null": 3.487078851427887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4060.json
index d037f07cbd3..6b836bbcea7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4060.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4060.json
@@ -1 +1 @@
-{"COAPROVEL": 38.136611886493945, "CYMBALTA": 1.5911524036265337, "null": 5.018499096748638}
\ No newline at end of file
+{"PEGINTERFERON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4061.json
index 9bcb2ed3bb2..854a231aaba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4061.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4061.json
@@ -1 +1 @@
-{"null": 2.6215031579876475}
\ No newline at end of file
+{"null": 0.855331966490197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4062.json
index c2cae7df9fd..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4062.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4062.json
@@ -1 +1 @@
-{"ENTRESTO": 110.26949182621678}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4063.json
index 6b772e6f601..4f7cb8d6fae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4063.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4063.json
@@ -1 +1 @@
-{"IBUPROFEN": 7.843914610653111, "PLAVIX": 4.375159934178359, "null": 1.692030047066947}
\ No newline at end of file
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4064.json
index c82dd5e0279..e334315fbcf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4064.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4064.json
@@ -1 +1 @@
-{"null": 4.802594096429057}
\ No newline at end of file
+{"ELIQUIS": 36.10335257895988, "null": 0.5404806822656967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4065.json
index 9d0428b6694..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4065.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4065.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 1.7655280234339252, "LEVOFLOXACIN": 7.724384290183256, "PLAVIX": 1.242224690893144, "null": 14.64569272558812}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4066.json
index 3a5d98414d9..6cc0aea1106 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4066.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4066.json
@@ -1 +1 @@
-{"null": 1.9524642654359792}
\ No newline at end of file
+{"SIMPONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4067.json
index 5dcfe3f256d..36ec61c3486 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4067.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4067.json
@@ -1 +1 @@
-{"ASPARAGINASE": 23.917903852160908, "DEXAMETHASONE": 6.548779357266675, "KYMRIAH": 57.89219235225119, "ONCASPAR": 136.5486105268739, "ROACTEMRA": 84.09788450445117, "TOCILIZUMAB": 615.2547251291676}
\ No newline at end of file
+{"null": 4.8229311646374615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4068.json
index a12dad9f759..5b5e4a8b328 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4068.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4068.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 13.786378272875783, "AMIKACIN": 13.352707042156537, "AUBAGIO": 2.188316885354747, "AXICABTAGENE": 81.93672085599854, "BORTEZOMIB": 24.2398337978363, "BUDESONIDE": 5.500930288797684, "CARFILZOMIB": 19.84885522181084, "CELLCEPT": 9.929377026422848, "CICLOSPORIN": 6.800434074061824, "CYTARABINE": 29.900991162195343, "DARZALEX": 18.189020058063782, "DEXAMETHASONE": 9.88775939603276, "DOXORUBICIN": 7.427778595904688, "FILGRASTIM": 18.21006282910948, "GLYCOPYRRONIUM": 34.792259578287414, "JAKAVI": 3.3704318110371605, "KEPPRA": 1.418090559919206, "KYMRIAH": 140.2758781423761, "MABTHERA": 15.9027082667804, "METHOTREXATE": 5.217861004154536, "MYCOPHENOLATE": 7.769776719502889, "OBINUTUZUMAB": 55.98488618870621, "RITUXIMAB": 26.44616565656873, "YESCARTA": 78.53503916656763}
\ No newline at end of file
+{"null": 6.8497097717139495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4069.json
index 16dded07374..b12ba2ea4d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4069.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4069.json
@@ -1 +1 @@
-{"CHAMPIX": 1.666255910469532, "COMIRNATY": 1.5233008168756983, "SPIKEVAX": 1.096224360378138, "SUTENT": 11.051951425204097, "XTANDI": 2.106872608271572, "null": 1.1630128099546757}
\ No newline at end of file
+{"COMIRNATY": 1.169149329838129, "ELIQUIS": 12.259942976730905, "null": 0.4116860675088356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/407.json
index c7a1313fd28..f852392bcda 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/407.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/407.json
@@ -1 +1 @@
-{"null": 1.270903590119421}
\ No newline at end of file
+{"null": 1.7915408011315832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4070.json
index 0deedea86ee..fe4d78637d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4070.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4070.json
@@ -1 +1 @@
-{"ABASAGLAR": 27.4716490677543, "ACOMPLIA": 7.467925153294567, "ACTOS": 19.16392981556364, "ACTRAPHANE": 55.76034105879474, "ACTRAPID": 48.13936637651637, "APIDRA": 42.34131185817496, "AVANDIA": 1.5120234171997189, "BAQSIMI": 45.51686243448775, "BYDUREON": 1.516129779096423, "BYETTA": 2.4454183994974703, "CANAGLIFLOZIN": 9.884787460127573, "COMPETACT": 52.72942209775195, "CORTICOSTEROID": 4.263958426578721, "CORTICOSTEROIDS": 1.9157424331255255, "DAPAGLIFLOZIN": 10.995819153771272, "DENOSUMAB": 1.381484621793372, "DEVICE": 21.92506809467372, "DRUG": 6.387249502111086, "DULAGLUTIDE": 6.799041223318199, "EFFICIB": 13.731326204878052, "EMPAGLIFLOZIN": 4.397203672589612, "ENVARSUS": 4.931146788071819, "EUCREAS": 7.1271169551344205, "EXUBERA": 7.456201877066892, "FIASP": 24.243658807805605, "FORXIGA": 4.319723087341925, "GALVUS": 6.824173978957802, "GLIBENCLAMIDE": 51.17085652926136, "GLUCAGON": 7.743640885452296, "HEMANGIOL": 23.191139644224226, "HUMALOG": 23.835807177441875, "INSULATARD": 35.31210921510065, "INSULIN": 38.39556059638405, "INSUMAN": 28.73926687814118, "INVIRASE": 1.0222781762383604, "INVOKANA": 2.6032883215117533, "ISOPHANE": 19.694263748522214, "JANUMET": 3.826717663323439, "JANUVIA": 7.818833163262205, "JARDIANCE": 2.4305338327709256, "LANTUS": 35.50558244318425, "LEVEMIR": 23.534065387498018, "LEVOFLOXACIN": 1.3760930907810995, "LINAGLIPTIN": 14.510139571270685, "LIPROLOG": 10.240657872103307, "LIRAGLUTIDE": 4.73612977433626, "LYUMJEV": 14.840986533815109, "MERCAPTOPURINE": 1.1395934309696163, "METFORMIN": 5.966320988171951, "MICARDIS": 2.0675464773376917, "MIXTARD": 34.55391722451432, "MOUNJARO": 10.871861929520716, "NOVOMIX": 35.05767410149898, "NOVONORM": 71.20607597732156, "NOVORAPID": 35.701191685792395, "ONGLYZA": 2.1382806211245957, "OZEMPIC": 2.4397341665644445, "PIOGLITAZONE": 16.123977300365524, "PRANDIN": 13.256137182522496, "PROPRANOLOL": 1.8364648013228957, "PROTAPHANE": 39.817111793820665, "REPAGLINIDE": 71.80485213169372, "RYBELSUS": 1.0553467411215696, "SAXAGLIPTIN": 13.641553716214377, "SAXENDA": 1.3380264892529243, "SEMAGLUTIDE": 2.0805126115547115, "SILDENAFIL": 1.000612035324015, "SITAGLIPTIN": 13.790223559575583, "SOMATROPIN": 2.576678649672792, "TOUJEO": 16.312080791874546, "TRAJENTA": 32.592981874841975, "TRESIBA": 44.71434145469532, "TRULICITY": 2.7280772953959924, "VELMETIA": 1.6964877505692084, "VFEND": 1.325624808872017, "VICTOZA": 2.625835609032304, "VILDAGLIPTIN": 11.471835693692643, "XELEVIA": 12.430179345498235, "ZYPREXA": 1.0429471769087095}
\ No newline at end of file
+{"AVANDIA": 3.4631106045619933, "CLOPIDOGREL": 5.847809945800048, "COMIRNATY": 0.4684468375203706, "DEXAMETHASONE": 2.022854499494132, "ELIQUIS": 48.87551497450573, "LIXIANA": 25.81648769626895, "NOVOSEVEN": 27.60877028983399, "NPLATE": 5.517723805720633, "PLAVIX": 4.019770195759928, "PRADAXA": 19.751723426223187, "SPIKEVAX": 0.3233697111146132, "TOZINAMERAN": 0.3681208372678809, "VAXZEVRIA": 0.3326896085453857, "XARELTO": 9.72745224184898, "null": 0.7433429936616587}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4071.json
index 3bc98eb83c7..7bc13069f40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4071.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4071.json
@@ -1 +1 @@
-{"ABILIFY": 7.045818457262448, "APIDRA": 6.384772064162495, "COAPROVEL": 18.34306649100582, "HUMALOG": 7.402147314719574, "INSULATARD": 81.07501212520336, "INSULIN": 51.74019821807413, "KEPPRA": 2.972033016891591, "LANTUS": 10.928689300473009, "LEVEMIR": 34.73321346683186, "LEVETIRACETAM": 4.509074734901488, "NOVORAPID": 13.321213904900002, "SUBOXONE": 7.794614060569295, "null": 1.5640755233591908}
\ No newline at end of file
+{"APIXABAN": 3.1417242366322897, "AVASTIN": 5.576337448926301, "BEDAQUILINE": 3.407040151654625, "BEVACIZUMAB": 5.380435493848728, "BLINATUMOMAB": 18.088366983540254, "CLOPIDOGREL": 1.266560262741545, "COMIRNATY": 0.5753543256663504, "CUBICIN": 7.065997068771261, "CYTARABINE": 1.1331205631898225, "DEXAMETHASONE": 3.733981138126457, "ELIQUIS": 5.627175135665634, "ENOXAPARIN": 7.126602790547773, "EVISTA": 45.98919886185333, "FASLODEX": 2.9769294437352274, "FENTANYL": 1.000308297255125, "FORSTEO": 1.5555879560765962, "HUMAN": 5.010424785076559, "HUMIRA": 1.3415887719936492, "IBRANCE": 0.7294295297634362, "JAKAVI": 2.123906130089238, "KEYTRUDA": 0.5801241744308013, "LANTUS": 0.4760094518553163, "METHOTREXATE": 1.0526285025341346, "NOVOSEVEN": 33.62984673505934, "NPLATE": 19.10742456150288, "PEGFILGRASTIM": 21.819417677679464, "PLAVIX": 0.6896780858687638, "PROTELOS": 10.693648234357148, "RINVOQ": 5.12286971818122, "ROACTEMRA": 1.5549272360066413, "SPIKEVAX": 0.2558358290243753, "SUTENT": 0.6547634619919223, "THALIDOMIDE": 9.526398187641204, "TOZINAMERAN": 1.52596068153426, "VAXZEVRIA": 1.4917758198780968, "XELJANZ": 1.269462430433879, "ZYPREXA": 1.463707694964825, "null": 0.731438567410632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4072.json
index 7cb3c70ad41..3dc5f182842 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4072.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4072.json
@@ -1 +1 @@
-{"APIDRA": 12.24910543048068, "HUMALOG": 81.60970471558056, "INSULIN": 36.93383428644884, "LANTUS": 23.61696632267947, "LEVEMIR": 35.38645981053781, "NOVORAPID": 61.924815308449226, "TRESIBA": 55.28012463875248}
\ No newline at end of file
+{"COMIRNATY": 0.525551447368291, "ELIQUIS": 4.459787746908269, "SPIKEVAX": 0.282916952648757, "VAXZEVRIA": 0.5899823878335283, "null": 0.79819539670504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4073.json
index 75be375392a..6ce44730552 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4073.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4073.json
@@ -1 +1 @@
-{"ABASAGLAR": 9.719689281518743, "ACTOS": 12.834957152131125, "ACTRAPHANE": 170.29349442168697, "ACTRAPID": 64.03942587244862, "APIDRA": 26.75085237494848, "BUPRENORPHINE": 3.259739869796056, "BYDUREON": 1.156642252336292, "DAPAGLIFLOZIN": 45.818997838559646, "FORXIGA": 2.455203147437629, "GALVUS": 2.7076728133784727, "GLIBENCLAMIDE": 39.63162497496122, "GLUCAGON": 11.010667654901065, "HUMALOG": 26.64737693109664, "INSULATARD": 34.002637622298, "INSULIN": 41.795373610938746, "INSUMAN": 35.20144740261754, "JANUMET": 2.089239798404699, "JANUVIA": 7.876784529663348, "LANTUS": 32.332054419103045, "LEVEMIR": 28.799798076918613, "MIXTARD": 117.8720885637614, "NOVOMIX": 165.189958337253, "NOVONORM": 124.80168898165324, "NOVORAPID": 40.732862030309256, "ONGLYZA": 4.400593851614851, "PIOGLITAZONE": 27.96394571728185, "PRANDIN": 104.73430579604802, "PROTAPHANE": 52.756719255320775, "REPAGLINIDE": 74.39386919495901, "TOUJEO": 2.698932040269262, "TRESIBA": 28.577169929718732, "VILDAGLIPTIN": 17.5055450558708, "null": 1.1250007493607812}
\ No newline at end of file
+{"ASPARAGINASE": 10.76203789058176, "AVASTIN": 12.899617571292591, "BEVACIZUMAB": 7.702461443491805, "BUDESONIDE": 5.154034674399293, "COMIRNATY": 0.3182352752558116, "ELIQUIS": 10.940641804632277, "ENOXAPARIN": 21.319653710963607, "EVISTA": 66.78943225919956, "NOVOSEVEN": 26.891865923093462, "OLANZAPINE": 15.406257381372429, "PEGASPARGASE": 191.89311462798915, "RINVOQ": 14.991067074716028, "SPIKEVAX": 0.2328318156394445, "TOZINAMERAN": 0.5145560332483401, "VAXZEVRIA": 0.5201344681632319, "XELJANZ": 2.6963874119139417, "null": 0.6271050299639002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4074.json
index f9e800edada..d09347314ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4074.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4074.json
@@ -1 +1 @@
-{"APIDRA": 26.810776635127752, "FORXIGA": 12.465053757170208, "GLIBENCLAMIDE": 109.90323462233904, "HUMALOG": 9.389388590552498, "INSULIN": 39.83663393846316, "JANUVIA": 18.55567434269789, "LANTUS": 12.699629962793276, "LEVEMIR": 20.251674391830758, "NOVORAPID": 35.47961488533972, "TRESIBA": 55.52741387045964, "null": 1.193716217061653}
\ No newline at end of file
+{"COMIRNATY": 0.143300744022799, "IBUPROFEN": 7.76404271422803, "NUCALA": 7.679397107297966, "OPSUMIT": 15.422142977815277, "null": 3.1374373267530427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4075.json
index 202812af23f..c9430f1ddc8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4075.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4075.json
@@ -1 +1 @@
-{"ACTRAPID": 29.959368756581004, "APIDRA": 30.74112026948308, "GLUCAGON": 34.40708570720253, "HEMANGIOL": 309.97633300646106, "HUMALOG": 38.83323533030466, "INSULIN": 20.139371009611352, "LANTUS": 76.27238200974567, "LEVEMIR": 42.525194626210286, "NOVONORM": 45.6029861522495, "NOVORAPID": 30.327697679174417, "TRESIBA": 32.33507975526325}
\ No newline at end of file
+{"VOTRIENT": 16.49954482242419, "null": 6.321761346951351}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4076.json
index 073caf038ce..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4076.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4076.json
@@ -1 +1 @@
-{"ACTRAPID": 29.317153712174655, "APIDRA": 36.21847582303528, "BAQSIMI": 180.40315723235517, "BYETTA": 3.6482375602523343, "FIASP": 20.909130686505648, "GLUCAGON": 29.10304710028644, "HUMALOG": 38.73787878089617, "INSULATARD": 40.13525184457348, "INSULIN": 30.217602853456096, "LANTUS": 70.97806406373125, "LEVEMIR": 66.29622330524269, "NOVONORM": 11.314966706868717, "NOVORAPID": 49.929967348883615, "SAXENDA": 3.59117805970665, "TOUJEO": 4.741306184073823, "TRESIBA": 78.91608763242286, "TRULICITY": 1.173186825204085, "VICTOZA": 4.285409504948167}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4077.json
index 1d568587136..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4077.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4077.json
@@ -1 +1 @@
-{"CYTARABINE": 7.301649011767729, "ZYPREXA": 3.4909112197528485, "null": 3.9486427027687303}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4078.json
index 8e60297e654..b33a42c29d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4078.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4078.json
@@ -1 +1 @@
-{"ZOSTAVAX": 16.99356960924383, "null": 2.9839020141957677}
\ No newline at end of file
+{"ABACAVIR": 0.4631345457925283, "ABILIFY": 4.2377895467052085, "AIMOVIG": 0.7295201743126254, "ARAVA": 0.115892702958935, "ARIPIPRAZOLE": 1.7440875361176609, "ASPARAGINASE": 3.212743310736533, "AUBAGIO": 0.9442918708645368, "AVANDIA": 0.6623741717507177, "BENLYSTA": 2.820879035883171, "BEXTRA": 17.042091928144742, "BIKTARVY": 2.010543519809912, "BRINTELLIX": 1.538502149619607, "BRIVIACT": 11.873902606605606, "BUPRENORPHINE": 1.765061976892203, "CHAMPIX": 11.24919960107046, "CIMZIA": 0.274645959040436, "COMIRNATY": 0.1790547137755697, "CYMBALTA": 2.6060879139155806, "DULOXETINE": 1.569377125598988, "ELIQUIS": 0.7120853124633528, "ELLAONE": 4.808722830383373, "ENBREL": 1.0722635962189302, "EXFORGE": 1.5822862077678217, "FENTANYL": 4.020562792390315, "FYCOMPA": 3.707431638699628, "GARDASIL": 1.0403727544745316, "HUMALOG": 0.5415022225487223, "HYDROCORTISONE": 2.4748541453047777, "IBRANCE": 2.5719950340618736, "IBUPROFEN": 1.842772846295376, "INCIVO": 2.001472889594369, "INVEGA": 11.593336288808644, "JANUMET": 1.843303572420662, "JANUVIA": 0.8525917139731437, "KAFTRIO": 3.6378441948814815, "KEPPRA": 5.790214324942186, "LATUDA": 2.8932844919848923, "LEVETIRACETAM": 2.2513120162268887, "LEVOFLOXACIN": 0.4300750553450089, "LYRICA": 2.1818009061172, "MEPOLIZUMAB": 1.0716658817886973, "OLANZAPINE": 1.213447756037363, "OMALIZUMAB": 0.6884784213825034, "ORKAMBI": 5.099836298815795, "PEGASYS": 2.4549170492396573, "PEGINTRON": 0.9235782497766748, "RIBAVIRIN": 1.8258705068048544, "RISPERIDONE": 6.337126418785396, "SIFROL": 4.114688556790301, "SILDENAFIL": 2.322314766399705, "SIMPONI": 0.3683127509241132, "SPIKEVAX": 0.1503018983073923, "STELARA": 0.2931888512886959, "SUBOXONE": 1.30552363877839, "SUTENT": 1.1629462761466798, "TAMIFLU": 1.015501101790476, "TOVIAZ": 1.637884778090844, "TOZINAMERAN": 0.9230662850968092, "TRODELVY": 8.24960300324811, "VAXZEVRIA": 0.2178532179605511, "VIAGRA": 0.9078853713020358, "XELJANZ": 0.6994295602526128, "XOLAIR": 1.5308672759311206, "XTANDI": 0.7372270147214729, "ZOSTAVAX": 0.3738456466241942, "ZYPREXA": 2.3817556488502776, "null": 2.1834726001483777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4079.json
index 63900ba5b39..8bc03940307 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4079.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4079.json
@@ -1 +1 @@
-{"null": 4.17329705998042}
\ No newline at end of file
+{"null": 2.0363559482475493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/408.json
index f4ac87ea550..314e55022cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/408.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/408.json
@@ -1 +1 @@
-{"null": 3.792326896754684}
\ No newline at end of file
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4080.json
index 0c4f139d41a..f935db947fd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4080.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4080.json
@@ -1 +1 @@
-{"ABIRATERONE": 9.00798235062046, "ABRAXANE": 1.0979380799069636, "ADCIRCA": 1.1842887253035237, "AERIUS": 1.4298901616706718, "ALIMTA": 1.0147733382505175, "ALISKIREN": 1.1885256126770287, "ALOXI": 4.068647694150727, "AMINOSALICYLIC": 4.100992357832779, "ANTIBIOTICS": 2.498696863856688, "APROVEL": 1.1592451328436115, "ATEZOLIZUMAB": 5.313904244089062, "AVELUMAB": 2.020972390119396, "AZACITIDINE": 1.0920705792427443, "BEDAQUILINE": 5.101122412784428, "BEVACIZUMAB": 1.3761929550086611, "BUMETANIDE": 6.936315030390356, "BYETTA": 1.1891865025544248, "CANCIDAS": 12.372192338058692, "CAPECITABINE": 2.2286791241588912, "CARFILZOMIB": 1.0706894944604306, "CASPOFUNGIN": 3.2962384201566173, "CELECOXIB": 1.8470558652082345, "COAPROVEL": 22.442198740846703, "COMTAN": 1.0403609654349002, "COTELLIC": 1.4519748045641463, "CYTARABINE": 1.2388389460191978, "DELAMANID": 7.562096794244004, "DESLORATADINE": 1.2115747719126957, "DOCETAXEL": 1.312099296299155, "EFAVIRENZ": 1.0472779420658629, "EMEND": 1.309127653832956, "ENZALUTAMIDE": 1.8186622937215984, "ERBITUX": 2.252483852069027, "ESOMEPRAZOLE": 1.4025215720102668, "EXFORGE": 1.5076125189327831, "FILGRASTIM": 2.629480043611476, "GANCICLOVIR": 1.4940753490773382, "GLIBENCLAMIDE": 1.5011229063327238, "HALAVEN": 1.4716604394848254, "HEPSERA": 1.5165682086924843, "HYDROCHLOROTHIAZIDE": 26.44071193552828, "HYDROCORTISONE": 1.3511914755260923, "IBUPROFEN": 1.2060438762555843, "INCIVO": 1.0196572204912042, "INOTUZUMAB": 21.139591143737825, "INSULIN": 1.5733533625668377, "INVIRASE": 3.1373967681054253, "IRBESARTAN": 3.857191535637191, "IRINOTECAN": 2.2057721660785337, "JANUVIA": 1.2640905816664725, "JEVTANA": 1.1745439050932978, "KALETRA": 1.3703364108066125, "KARVEZIDE": 14.04686425956964, "KYPROLIS": 1.013743594642991, "LACOSAMIDE": 2.6388937202681504, "LENALIDOMIDE": 1.9958255966292588, "LOKELMA": 46.09987669538091, "LOPINAVIR": 1.981958425279532, "LYSODREN": 3.327568512886822, "MANNITOL": 3.987309188677058, "MICAFUNGIN": 5.424385890857232, "MICARDISPLUS": 6.3623501141381125, "NERLYNX": 5.145997831943793, "NOVONORM": 1.06834544205065, "NOXAFIL": 18.0082903154935, "PANTOPRAZOLE": 2.0284315296010758, "POSACONAZOLE": 5.980548155225688, "PRITORPLUS": 15.130603851658217, "PROCORALAN": 6.001550414634785, "RASILEZ": 2.2121733257128118, "SAMSCA": 6.69753829212873, "SIRTURO": 3.030467415493918, "SPINRAZA": 1.2815425408816117, "SPIRONOLACTONE": 4.438349673040297, "TELMISARTAN": 2.273463676710508, "TENOFOVIR": 4.552127168458829, "TOPOTECAN": 1.2099566087477844, "VECTIBIX": 1.3972481598511708, "VELCADE": 1.932228816969534, "VFEND": 2.1022499276429425, "VIREAD": 1.0833969542394868, "VORICONAZOLE": 2.495424746309905, "XELODA": 1.2102592297143937, "ZOMETA": 2.356209244741283, "ZYPREXA": 1.0838157436011884, "ZYTIGA": 31.003792064069334, "null": 5.568785019220675}
\ No newline at end of file
+{"ABILIFY": 0.499471605962082, "ABLAVAR": 161.85208465362794, "ACETAMINOPHEN/OXYCODONE": 11.540852615818826, "ADALIMUMAB": 0.0348192038846332, "ARAVA": 0.028354404522785, "ARIPIPRAZOLE": 0.1486301464223162, "ATRIPLA": 45.881260610515625, "AVAMYS": 0.1360587331765006, "AVANDAMET": 0.3288353523932646, "AVANDIA": 0.3205985918585608, "BENLYSTA": 0.2800542772816537, "BEOVU": 0.534925759494789, "BIKTARVY": 0.3821028036099834, "BONVIVA": 1.6359948185263578, "BORTEZOMIB": 1.0076102891502814, "BRINTELLIX": 0.273998964186859, "BUDESONIDE": 1.780770350595074, "BUPIVACAINE": 1.0395427386008709, "BUPRENORPHINE": 1.9257699880914656, "BYETTA": 0.4146456429893533, "CHAMPIX": 0.69184733393777, "CIALIS": 9.361178518236857, "CICLOSPORIN": 0.0797574324582287, "COMIRNATY": 0.0467865318224467, "CONTRAST": 4.303460161890472, "COSENTYX": 0.236883045879049, "CYMBALTA": 0.2755703554211822, "CYTARABINE": 0.1241338786671398, "DEXAMETHASONE": 0.1646163465450493, "ELIQUIS": 0.0393811644954641, "ENBREL": 0.1103765230497036, "FENTANYL": 0.6454017548079438, "FLEBOGAMMA": 0.8138872581489436, "GARDASIL": 0.3303752240343456, "HUMALOG": 0.0964381018875098, "HYDROCORTISONE": 0.2024437191557883, "IBRANCE": 0.1065092967571837, "IBUPROFEN": 0.3032782504961716, "INVEGA": 1.8990244487402523, "JANUMET": 0.4574915656024179, "JARDIANCE": 0.053042354103385, "KAFTRIO": 0.3124397942368178, "KALETRA": 1.5779605668794072, "KEPPRA": 0.0947487818646838, "LANTUS": 0.0524222627683271, "LATUDA": 1.0659590791837863, "LEVOFLOXACIN": 0.2306404092045181, "LYRICA": 0.1852541957375642, "MEPOLIZUMAB": 0.1597781115586704, "MIDAZOLAM": 0.2658472736624035, "NALOXONE": 2.081520108533881, "NIMENRIX": 0.1701272317967082, "NUCALA": 0.3980546762328552, "OCRELIZUMAB": 0.4134825940128834, "OLANZAPINE": 0.4400250114736008, "OPTIMARK": 16.79590190336354, "PANTOPRAZOLE": 0.2432631393120992, "PEGASYS": 0.1682191027815974, "PLAVIX": 0.1398266507999101, "PLEGRIDY": 0.2626819144597764, "RISPERIDONE": 0.8713628858747785, "SHINGRIX": 0.2344263530864913, "SILDENAFIL": 0.4715207226070714, "SIMPONI": 0.1808525546196456, "SPIKEVAX": 0.0361085067674968, "STELARA": 0.1049151820336336, "STRIBILD": 31.391290817044823, "SUBOXONE": 0.4627400414160385, "SUTENT": 0.047636620959347, "TAMIFLU": 0.4298352429081618, "TASIGNA": 7.997504827632006, "TOZINAMERAN": 0.128019432999323, "TRUVADA": 30.04732525117182, "VAXZEVRIA": 0.0332077528408351, "VIAGRA": 0.8920533556056225, "VIMPAT": 0.2287774802487543, "VIREAD": 18.20795610370266, "XELJANZ": 0.0989308844018647, "XOLAIR": 0.0943928197100846, "ZOSTAVAX": 1.1406207804913018, "ZYPREXA": 0.3003358090123615, "null": 0.4874695144686595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4081.json
index 9f9ad43cc94..3550f856dfe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4081.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4081.json
@@ -1 +1 @@
-{"null": 1.7602521017145338}
\ No newline at end of file
+{"ABILIFY": 5.321498001344082, "BRINTELLIX": 6.7753003617441445, "CHAMPIX": 9.420701779334095, "COMIRNATY": 0.0817859659859599, "CYMBALTA": 5.28269646569605, "LATUDA": 13.5690236058716, "ZYPREXA": 7.611317837003887, "null": 3.419388857502596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4082.json
index aed16f5bdd8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4082.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4082.json
@@ -1 +1 @@
-{"ACLASTA": 11.31175437897931, "AUBAGIO": 1.4760916327562557, "BUMETANIDE": 5.565785141340589, "BYDUREON": 1.3317326132178977, "COMIRNATY": 1.053237876516993, "COMTAN": 4.05035611719886, "COMTESS": 43.0847079988824, "COSENTYX": 1.218729668695694, "CYMBALTA": 4.018818801496984, "DASATINIB": 6.810363740036559, "DULOXETINE": 6.30601073742953, "ENOXAPARIN": 1.538439956453382, "ENTACAPONE": 12.360679957870936, "ENTRESTO": 3.0643111319493146, "EXFORGE": 1.569265262700844, "FORSTEO": 1.7412297093501543, "GARDASIL": 1.1675782536100208, "IBUPROFEN": 1.0832808605280544, "IRBESARTAN": 8.09776737822522, "KEPPRA": 1.0470752088486572, "LANTUS": 1.0938582652331172, "LEVODOPA": 5.186140096993126, "LYRICA": 1.648215793959137, "MIDAZOLAM": 1.2596961724124094, "NAGLAZYME": 2.110000820419972, "OLANZAPINE": 1.592507177857825, "PANTOPRAZOLE": 1.7128798163473182, "SIMPONI": 1.503641064959954, "STALEVO": 10.896466820444084, "TOUJEO": 1.8192295609003557, "TOZINAMERAN": 2.4754429243777434, "TWINRIX": 2.02786042749427, "XELJANZ": 2.070400302209489, "XOLAIR": 1.255566091284958, "ZYPREXA": 1.6382671411959502, "null": 1.155445872800413}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4083.json
index 6d1a2432522..532ad18f966 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4083.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4083.json
@@ -1 +1 @@
-{"null": 5.198964971256344}
\ No newline at end of file
+{"ACLIDINIUM": 35.37101046229918, "AFINITOR": 1.5062393461558825, "ANORO": 11.374434353079742, "ARAVA": 0.1829677334603068, "BUDESONIDE": 6.312721943956484, "BUPRENORPHINE": 1.8836241403546432, "BYETTA": 1.463172115383406, "CHAMPIX": 3.239620643938389, "COMIRNATY": 0.11399025572352, "COSENTYX": 0.5875022249128756, "CYMBALTA": 0.8635962637369251, "DAPAGLIFLOZIN": 10.296138580794665, "DEXAMETHASONE": 0.9198303877437228, "DULOXETINE": 2.744072968163017, "ELIQUIS": 0.5958589350610943, "ENBREL": 1.8733819813069896, "ESBRIET": 1.8562648532016524, "FORSTEO": 2.021449684948051, "GLYCOPYRRONIUM": 11.609128297957133, "HUMALOG": 1.0230065715693142, "HUMIRA": 1.629734078710942, "IBRANCE": 0.4489689944314333, "IBUPROFEN": 1.4339201238737234, "INCRUSE": 6.027904355666179, "JANUMET": 5.181003329842802, "JANUVIA": 2.226606735218453, "KEYTRUDA": 1.8914030722438295, "LANTUS": 1.2384478295211323, "MEPOLIZUMAB": 6.736869588419506, "MICARDIS": 2.652321428572374, "MULTAQ": 4.678500418194788, "NUCALA": 4.240826271551405, "OLANZAPINE": 0.8147979924792573, "OMALIZUMAB": 1.9822091123836103, "OPSUMIT": 1.7673337763162624, "PEGASYS": 0.7974610336751522, "PEGINTRON": 1.2308127133147555, "PEMBROLIZUMAB": 2.354118053353282, "RELVAR": 3.849993342152198, "REVATIO": 2.874387413230555, "RITUXIMAB": 1.2937566863939152, "SEEBRI": 44.10726862854626, "SIMPONI": 2.0984131112964737, "SPIKEVAX": 0.1257684898711424, "SUTENT": 0.4742579649675686, "TOZINAMERAN": 0.1935665702610133, "TRACLEER": 1.6746017257059138, "TRELEGY": 15.789408401476448, "ULTIBRO": 91.47627680376856, "VAXZEVRIA": 0.0516600961682175, "XARELTO": 2.5593348205418978, "XELJANZ": 0.8854536416526884, "XOLAIR": 1.9627429534328693, "ZOSTAVAX": 3.454363271149943, "null": 1.9161730497347895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4084.json
index ec9123cd69f..87af6754935 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4084.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4084.json
@@ -1 +1 @@
-{"ALIMTA": 2.4718487309531003, "AMIKACIN": 4.913407135136728, "AMINOSALICYLIC": 13.267905181399106, "ANAKINRA": 6.48349124968415, "APIXABAN": 1.1803721319803393, "ASPARAGINASE": 1.851655033638069, "ATEZOLIZUMAB": 54.74344519866453, "AVASTIN": 3.229284732308967, "BEDAQUILINE": 24.27125694728228, "BEVACIZUMAB": 6.844847831025537, "BRAFTOVI": 4.4677448413371055, "BUMETANIDE": 21.3094339833183, "BUSULFAN": 1.8306425633747987, "BYETTA": 2.773870839339415, "CABOMETYX": 7.627779476893026, "CANCIDAS": 10.672039843379068, "CASPOFUNGIN": 6.368665930082398, "CELLCEPT": 2.350438161000631, "CETUXIMAB": 20.937169901068646, "CICLOSPORIN": 2.3986499899020566, "CINACALCET": 29.49062506154964, "CLOPIDOGREL": 2.0345571342017026, "COAPROVEL": 3.831961575319198, "CYTARABINE": 1.294522967077707, "DELAMANID": 11.311169249808838, "DOCETAXEL": 2.303911105122637, "ERBITUX": 46.40220842134673, "ESOMEPRAZOLE": 11.301567551637548, "FILGRASTIM": 11.471376767103354, "FIRDAPSE": 6.584150088676262, "GANCICLOVIR": 4.873743236638839, "GLIBENCLAMIDE": 11.499718958336542, "HYDROCORTISONE": 3.821049958365553, "INOTUZUMAB": 132.8584058253871, "IPILIMUMAB": 3.41010329683911, "IRBESARTAN": 3.911402930919412, "IRINOTECAN": 13.327159290455429, "JANUMET": 3.160496023094699, "JANUVIA": 1.9410969640245472, "KEYTRUDA": 1.59407161294586, "LEVETIRACETAM": 7.557550461647026, "LEVOFLOXACIN": 3.0398567391453235, "LYRICA": 1.9344931970674335, "NEXAVAR": 1.6308536579623334, "NOXAFIL": 13.258917634714832, "PANITUMUMAB": 104.78900949670944, "PANTOPRAZOLE": 18.934579906530296, "POSACONAZOLE": 13.744022326403568, "RIBAVIRIN": 12.208683398658328, "VECTIBIX": 171.51108215756383, "VELTASSA": 7.97588770792165, "VFEND": 2.216409683302376, "VILDAGLIPTIN": 29.407481795694157, "VOTRIENT": 1.131219814901105, "null": 1.2909997425597013}
\ No newline at end of file
+{"FORXIGA": 71.16557396619714, "JARDIANCE": 58.74051576045044, "null": 0.3410849526528416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4085.json
index b1df8d00cd3..60696b91238 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4085.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4085.json
@@ -1 +1 @@
-{"ABILIFY": 3.697783357189534, "ACLIDINIUM": 115.1590019708789, "ANORO": 6.456693255728992, "APTIVUS": 58.1016134272866, "ARIPIPRAZOLE": 16.67201745041211, "BREXPIPRAZOLE": 238.816437624049, "BRINTELLIX": 16.014805547764624, "CHAMPIX": 5.579466313599434, "COMTAN": 13.836712275631216, "CYMBALTA": 58.90137936013216, "ENTACAPONE": 18.694912954293475, "KEPPRA": 2.699385322973444, "LATUDA": 8.795684790603806, "LEVODOPA": 19.62073852543799, "OLANZAPINE": 7.622981146320928, "ZYPREXA": 4.824270892076987, "null": 1.472452713557282}
\ No newline at end of file
+{"JARDIANCE": 66.82818935348261}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4086.json
index 6476ca8cbf3..1c0c8810a8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4086.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4086.json
@@ -1 +1 @@
-{"COMIRNATY": 9.508405574782818, "COVID19": 1.79300767662866, "ELLAONE": 59.68453358266352, "SPIKEVAX": 2.151072070477509, "TOZINAMERAN": 3.3028808954912683}
\ No newline at end of file
+{"null": 4.403675619731737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4087.json
index 46605c331d6..9a63023789a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4087.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4087.json
@@ -1 +1 @@
-{"null": 1.3357237382070768}
\ No newline at end of file
+{"BEDAQUILINE": 21.85038051409052, "BORTEZOMIB": 50.05658309470043, "CICLOSPORIN": 2.6830172914730746, "COMIRNATY": 0.0724265878928931, "PEGASYS": 2.555324873058888, "ROACTEMRA": 12.173498664151271, "SPIKEVAX": 0.1728969423683765, "TOCILIZUMAB": 56.00855925329524, "null": 0.9790991280104836}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4088.json
index a2f00462a8b..7f7fac3de50 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4088.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4088.json
@@ -1 +1 @@
-{"ADCETRIS": 1.932128253063432, "ADENURIC": 1.1684821147537423, "AERIUS": 1.4676181412612288, "AGOMELATINE": 11.996810438920177, "ALIMTA": 1.2078663227247084, "ALOXI": 3.203744470085851, "APROVEL": 10.222136889710535, "ARANESP": 10.97572617095042, "ASPARAGINASE": 1.5822157041935403, "ATEZOLIZUMAB": 3.300203346687173, "BEDAQUILINE": 2.1437416290772644, "BEXTRA": 4.863811378765752, "BRINTELLIX": 3.923799953694836, "BRIVARACETAM": 3.1231792000907967, "BRIVIACT": 1.035400937933931, "BUMETANIDE": 4.37472754916349, "CABOMETYX": 1.2630990292667914, "CIRCADIN": 2.610295710324878, "COAPROVEL": 41.92083150239086, "COMBIVIR": 1.206713467292681, "CYMBALTA": 4.128274806220987, "DAPAGLIFLOZIN": 1.1320576144610068, "DARBEPOETIN": 26.794704673059627, "DESLORATADINE": 1.1966447080298597, "DULOXETINE": 2.5893723932869435, "EBIXA": 1.842085659771715, "EMEND": 4.6757248247046, "EMPAGLIFLOZIN": 1.8538301064663572, "ENTACAPONE": 3.0186994814974075, "ENTRESTO": 1.709450117493772, "ERBITUX": 1.903363921022916, "ESOMEPRAZOLE": 6.1934911328850415, "EVISTA": 1.1148008276148946, "EXELON": 3.1644517546599444, "EXFORGE": 3.413422691656688, "EXVIERA": 2.4919166937483785, "FILGRASTIM": 1.1276495763232417, "FIRDAPSE": 1.095567920094908, "FLUTICASONE": 4.003399027418299, "FORXIGA": 1.3669490815443963, "GONALF": 2.146020347678118, "HYDROCHLOROTHIAZIDE": 14.822155081241691, "IRBESARTAN": 10.27569665805074, "KARVEA": 6.337541657451082, "KARVEZIDE": 22.422652401041617, "KEPPRA": 2.3129990946120937, "KEYTRUDA": 1.5167037734907411, "LACOSAMIDE": 1.5908816775127204, "LENVIMA": 1.4245225283263558, "LEVETIRACETAM": 2.491222663930421, "MANNITOL": 4.607503304319176, "MEKINIST": 1.3172122221288427, "MEMANTINE": 2.622407360299305, "MICARDIS": 4.029462864451151, "MICARDISPLUS": 36.229688108395926, "NIVOLUMAB": 1.480298642149967, "NORVIR": 1.8897572371888165, "NOT": 1.102864331124094, "NOVONORM": 2.391470496955677, "NOXAFIL": 1.5310928945493048, "OLANZAPINE": 2.579177164353873, "OPDIVO": 1.8905913537606769, "OXYBUTYNIN": 1.066919992976948, "PANTOPRAZOLE": 5.084263988126934, "PRADAXA": 2.265995412356076, "PRITOR": 6.851189071467454, "PRITORPLUS": 43.86941329753903, "PROLIA": 7.665441288249248, "RANEXA": 4.21310433504435, "RASILEZ": 4.734463974048647, "RISPERIDONE": 1.0460097706488205, "RIVASTIGMINE": 16.34681190706136, "SAMSCA": 6.57251775209672, "SIFROL": 1.4996696078369336, "SPIRONOLACTONE": 10.753680909294111, "SUNITINIB": 1.911791117971736, "TACROLIMUS": 1.1048126148796924, "TAXOTERE": 1.4316604313275063, "TELMISARTAN": 4.158363038635899, "TORISEL": 1.5431268264156155, "VALSARTAN": 1.178870333479841, "VFEND": 1.5321312983290365, "VIMPAT": 1.24558304890133, "VORICONAZOLE": 1.6114160007814655, "VORTIOXETINE": 5.587325299030235, "YERVOY": 1.5335774624719771, "ZEBINIX": 71.49573461877132, "ZYPREXA": 2.8557417266785845, "ZYTIGA": 7.082231516235132, "null": 4.209493603969707}
\ No newline at end of file
+{"ASPARAGINASE": 73.1880328359359, "ATRIPLA": 4.178173781972772, "null": 1.900823485919936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4089.json
index 8c3894c4186..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4089.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4089.json
@@ -1 +1 @@
-{"null": 8.061190422622072}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/409.json
index 34fd2479421..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/409.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/409.json
@@ -1 +1 @@
-{"null": 1.024072688989114}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4090.json
index 02890111c0a..70e8dc74e26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4090.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4090.json
@@ -1 +1 @@
-{"SOMATROPIN": 386.1438015596223, "null": 5.10847007168488}
\ No newline at end of file
+{"CELSENTRI": 133.48611436397306, "COMIRNATY": 0.2108674642754139, "MMRVAXPRO": 6.144632904899591, "NEXAVAR": 6.288340282235854, "null": 2.483061688452629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4091.json
index f796a75262a..910ac5c64c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4091.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4091.json
@@ -1 +1 @@
-{"KEPPRA": 6.912856548091505, "null": 4.140350862180093}
\ No newline at end of file
+{"null": 3.181588098901945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4092.json
index 8d5712b19ea..21620340156 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4092.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4092.json
@@ -1 +1 @@
-{"null": 2.83139323334466}
\ No newline at end of file
+{"ABACAVIR": 0.8531047166347252, "AIMOVIG": 0.8233751291702189, "ALEMTUZUMAB": 3.543579612068537, "ARAVA": 0.1567807671218863, "ASPARAGINASE": 18.74000560066149, "AXITINIB": 6.39547186371706, "BRAFTOVI": 2.698300949610533, "BUSULFAN": 6.158706181686079, "CELLCEPT": 2.9139699641811867, "CICLOSPORIN": 3.2867599828732468, "CIMZIA": 1.2851168934373391, "COMIRNATY": 0.6113718074556337, "CYTARABINE": 4.314287024392828, "DEXAMETHASONE": 2.533197361953512, "EMTRICITABINE": 4.593915265610619, "ENTYVIO": 1.1520945626538688, "GARDASIL": 6.225442000031031, "HUMAN": 2.3338591239490163, "IPILIMUMAB": 10.559856827701788, "JAKAVI": 1.3676809964868923, "KALETRA": 2.4523281620958817, "KEPPRA": 1.738793006427461, "KEYTRUDA": 11.08818906213535, "LACOSAMIDE": 2.815508154519119, "LAMIVUDINE": 3.4205823407608933, "LEVETIRACETAM": 1.7107473342281874, "MEKINIST": 2.752920009748525, "METHOTREXATE": 3.2655082200524213, "MMRVAXPRO": 2.413283661116198, "MYCOPHENOLATE": 3.838708246930884, "NIMENRIX": 3.7071687956924055, "OPDIVO": 10.964496760472093, "PEGASYS": 0.3190271046219081, "PEGINTRON": 0.6158871820270815, "PEMBROLIZUMAB": 5.745263753749124, "RITUXIMAB": 0.9791184897387392, "ROACTEMRA": 2.117772511165185, "SHINGRIX": 3.387731826277921, "SIMPONI": 0.4980801430009666, "SOLIRIS": 1.043174129261341, "SPIKEVAX": 0.4418139218038084, "STELARA": 0.3964878898395662, "TAMIFLU": 4.245496048573253, "TOZINAMERAN": 0.6788468076118727, "TWINRIX": 6.3053796638871065, "VAXZEVRIA": 0.4946739277978229, "VIMPAT": 2.0739166053675566, "YERVOY": 3.6112130804300513, "ZOSTAVAX": 2.8113456251970748, "null": 0.8565579600785155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4093.json
index bd6a75f4dc8..4f588b04b7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4093.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4093.json
@@ -1 +1 @@
-{"LOXAPINE": 532.6009034077952, "VILDAGLIPTIN": 382.4531151659439, "null": 1.8306837329650412}
\ No newline at end of file
+{"AVONEX": 73.92084513678424, "BUSULFAN": 6.766895826225468, "COMIRNATY": 0.8669801021280338, "GARDASIL": 5.243879314143949, "HUMAN": 11.242805722955936, "IPILIMUMAB": 26.694867674898703, "KEPPRA": 6.879221247982857, "KEYTRUDA": 18.750212506874764, "LEVETIRACETAM": 16.196939528440094, "OLANZAPINE": 2.395997077733444, "OPDIVO": 13.15738855375916, "PEMBROLIZUMAB": 24.49146152563375, "SPIKEVAX": 0.6450297993407719, "TOZINAMERAN": 0.8543985618116144, "VAXZEVRIA": 0.5689595893126005, "null": 0.2690470271369314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4094.json
index 58b7d3e46f4..075da7432bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4094.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4094.json
@@ -1 +1 @@
-{"BORTEZOMIB": 110.2097281671077, "null": 2.417515590433675}
\ No newline at end of file
+{"null": 0.5151100200598595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4095.json
index 090acfaf527..835bef3d457 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4095.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4095.json
@@ -1 +1 @@
-{"ABRAXANE": 23.78003164441682, "ACETYLSALICYLIC": 59.72216539564591, "AFINITOR": 3.2685191469359127, "ALIMTA": 2.0094844354584547, "ALOXI": 23.469966448367465, "AMINOSALICYLIC": 1.2080809387372742, "ARIPIPRAZOLE": 3.1379962320046646, "ASPARAGINASE": 3.478961303036884, "AVASTIN": 1.286687058442996, "AXITINIB": 3.744226475444639, "BEVACIZUMAB": 1.420865638683811, "BYDUREON": 5.147988576922387, "BYETTA": 1.5778804474880963, "CABOMETYX": 1.6655054318203062, "CALCIUM": 62.20750315514399, "CAPECITABINE": 1.7452864427257333, "CEFTAROLINE": 129.91825049650234, "CYMBALTA": 1.0152002144016663, "CYTARABINE": 2.546276862235616, "DACLATASVIR": 6.911485154585296, "DOCETAXEL": 1.6456534598916246, "EMPAGLIFLOZIN": 3.110412544317012, "EPIVIR": 2.760550249175187, "ESBRIET": 2.218603879228362, "EXJADE": 3.079688626183204, "FASENRA": 1.1462985682760454, "FENTANYL": 1.318649883520878, "FIRDAPSE": 6.011332075825327, "FORSTEO": 1.3623557282630554, "FORXIGA": 2.833560573740726, "HERCEPTIN": 1.6848636232384226, "HUMALOG": 2.138261525220665, "HUMIRA": 1.9871526029531128, "IBUPROFEN": 1.4660849557039348, "INLYTA": 2.5742421675407163, "INSULIN": 1.0124177942937895, "IPILIMUMAB": 1.7673224108016343, "IRBESARTAN": 3.96570591413869, "IRESSA": 1.2706988285001797, "IRINOTECAN": 2.191803076310809, "JANUVIA": 1.1045538104205253, "JARDIANCE": 6.067664753534989, "KAFTRIO": 1.6389015132006337, "KALETRA": 2.3749194230790414, "KEYTRUDA": 1.84534149003536, "LEVETIRACETAM": 1.1968330851843232, "LONSURF": 2.41741965171428, "LYNPARZA": 1.747774875297784, "METFORMIN": 5.958762500351369, "MICARDIS": 1.48851896009671, "MMRVAXPRO": 1.269905497530626, "NEULASTA": 1.422812046790636, "NEXAVAR": 1.4028990341368934, "NIMENRIX": 1.2797970676426569, "OFEV": 4.469428165076442, "OLANZAPINE": 3.0593361504695524, "OMALIZUMAB": 2.0114990444954444, "PANTOPRAZOLE": 1.91906981788942, "PEGASYS": 1.2046630544598265, "PEGINTERFERON": 1.165128328053902, "PEGINTRON": 1.620009135387254, "PEMBROLIZUMAB": 1.180930829374501, "RINVOQ": 1.5629799183083612, "ROTATEQ": 15.891236686506671, "RUBRACA": 11.623187792810995, "SAXENDA": 1.3900453952344227, "SOMATROPIN": 6.471100344467632, "SPIRONOLACTONE": 4.001368138956946, "STIVARGA": 2.9216083736855487, "SUTENT": 4.352521262473482, "SYNAGIS": 9.238132289677166, "TAGRISSO": 2.2703870435921254, "TAMIFLU": 1.194042476230433, "TRULICITY": 3.879379726599245, "XALKORI": 1.8863328842668208, "XTANDI": 1.942318334635496, "null": 1.1411248900692323}
\ No newline at end of file
+{"ARAVA": 3.756943216475876, "COMIRNATY": 0.6775153449926906, "null": 0.3380527281218915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4096.json
index 3fcb2ee81fd..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4096.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4096.json
@@ -1 +1 @@
-{"ABACAVIR": 3.717831182234173, "AFINITOR": 2.031309109486191, "ARANESP": 62.26964528755798, "ATAZANAVIR": 5.922991596462227, "ATRIPLA": 1.4041395612357284, "BEVACIZUMAB": 2.0769990626770545, "CELLCEPT": 1.3417968677568202, "COMBIVIR": 4.32014210436532, "DEXAMETHASONE": 1.2916696475358158, "EMTRICITABINE": 18.33753547871697, "ENTECAVIR": 83.70592078534567, "EXJADE": 5.706767815221547, "FILGRASTIM": 6.124584341366077, "FIRDAPSE": 5.68891863279898, "GENVOYA": 15.986854278908874, "H2": 705.89987823997, "HARVONI": 3.0594080189507435, "HEPSERA": 389.2838046527665, "HYDROCORTISONE": 9.88939523519174, "JARDIANCE": 1.1447090717849544, "KALETRA": 12.548102452650392, "LEVETIRACETAM": 1.5159001115524982, "LOPINAVIR": 18.08519207367095, "MEKINIST": 1.691550120164067, "METHOTREXATE": 1.2191526407922446, "MIMPARA": 11.28326852222456, "NEXAVAR": 9.03541799987023, "NORVIR": 9.305293571570456, "STIVARGA": 5.704116111091675, "TASIGNA": 1.7551609107620911, "TENOFOVIR": 127.26828519478757, "TRUVADA": 4.832732673545217, "VIREAD": 70.21664773013512}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4097.json
index 829b00d0d4b..031824b6335 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4097.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4097.json
@@ -1 +1 @@
-{"HEPSERA": 1033.3298314677031, "TENOFOVIR": 846.721781779316, "VIREAD": 118.74644814920156}
\ No newline at end of file
+{"BUDESONIDE": 29.75618383806537, "BUSULFAN": 52.08368419280893, "CELLCEPT": 14.53292655086022, "CICLOSPORIN": 29.070315115526736, "GANCICLOVIR": 342.37811265980645, "null": 0.0810196428166956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4098.json
index d22aa6023dd..ce2ae0ef8b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4098.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4098.json
@@ -1 +1 @@
-{"AXITINIB": 17.305085328067893, "BRAFTOVI": 5.755737250224573, "IPILIMUMAB": 486.2967077921366, "KEYTRUDA": 39.63832308174628, "NIVOLUMAB": 43.84328165206169, "OPDIVO": 166.2949415065339, "PEMBROLIZUMAB": 41.53316971573458, "YERVOY": 349.16454064114987}
\ No newline at end of file
+{"CELLCEPT": 12.56515827925354, "CICLOSPORIN": 20.4749400290905, "COMIRNATY": 0.5810144582911533, "ERIBULIN": 454.3821086037361, "ROACTEMRA": 10.240426475032592, "ZOSTAVAX": 11.074995214800776, "null": 0.4196553986914231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4099.json
index fb37810fe8e..4aab17dd23b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4099.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4099.json
@@ -1 +1 @@
-{"AXITINIB": 34.941480539154895, "IPILIMUMAB": 88.60814365829427, "KEYTRUDA": 53.13344385945798, "OPDIVO": 224.7886056633029, "PEMBROLIZUMAB": 11.891688088871067, "YERVOY": 131.1982648591851}
\ No newline at end of file
+{"null": 2.1571591563082437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/41.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/41.json
index 4f3aaa28138..e9aaddb8388 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/41.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/41.json
@@ -1 +1 @@
-{"COMIRNATY": 7.039855133367335, "SPIKEVAX": 1.6025525654081352}
\ No newline at end of file
+{"NOVOSEVEN": 156.82509829685773, "null": 1.0351547204545708}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/410.json
index 8de7921f6d0..854a231aaba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/410.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/410.json
@@ -1 +1 @@
-{"APTIVUS": 784.0312787137402, "COMBIVIR": 46.60903777122272, "DESCOVY": 137.58390919058138, "null": 1.6013053701760562}
\ No newline at end of file
+{"null": 0.855331966490197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4100.json
index a47fe8b2331..a73c86dba65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4100.json
@@ -1 +1 @@
-{"null": 4.141223174152671}
\ No newline at end of file
+{"ALIMTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4101.json
index 76e7eb2d5be..f3f10dc649d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4101.json
@@ -1 +1 @@
-{"null": 9.65798831717102}
\ No newline at end of file
+{"GARDASIL": 25.140718493747272, "null": 1.1765281003619523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4102.json
index 0b0375724cb..16393d47cc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4102.json
@@ -1 +1 @@
-{"null": 5.731706343934361}
\ No newline at end of file
+{"null": 1.5399766571559377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4103.json
index 56f1ba7cf87..7b32222dbba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4103.json
@@ -1 +1 @@
-{"ADALIMUMAB": 5.766515764976311, "BUPIVACAINE": 9.75713982494687, "COVID19": 2.1231020009038053, "FENTANYL": 3.9371500958496126, "GARDASIL": 1.4801667311173543, "IBUPROFEN": 3.704401208047511, "KEPPRA": 1.0313133634965972, "LEVETIRACETAM": 1.5114519186744124, "MIDAZOLAM": 4.02092944542596, "OPSUMIT": 1.175393634377394, "PANTOPRAZOLE": 7.827678239651715, "SUBOXONE": 2.940634881613922, "TOZINAMERAN": 2.7796850447241885, "XOLAIR": 1.59959260588685, "null": 1.10351384366176}
\ No newline at end of file
+{"ALEMTUZUMAB": 47.95503344008096, "BUSULFAN": 19.629510530072903, "CELLCEPT": 5.894202360015541, "CICLOSPORIN": 15.40731814364185, "COMIRNATY": 0.2101747670162644, "GARDASIL": 2.555811670245405, "SHINGRIX": 4.670882081830588, "TOZINAMERAN": 0.6072788738270943, "VAXZEVRIA": 0.1716496714316731, "null": 0.6551896347754607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4104.json
index 656bfe0b430..77a82e689d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4104.json
@@ -1 +1 @@
-{"AMIKACIN": 26.12155459479332, "CELLCEPT": 5.555024966948186, "CICLOSPORIN": 4.0967528223071135, "CLOPIDOGREL": 2.0232260218516545, "NEXAVAR": 3.3533500723636074, "STIVARGA": 6.983315686377209, "SUTENT": 1.2773850606749286, "null": 1.552052012020613}
\ No newline at end of file
+{"COMBIVIR": 122.76418322146375, "null": 1.088422288245303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4105.json
index d739d0297b9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4105.json
@@ -1 +1 @@
-{"null": 14.45160416332334}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4106.json
index c4a13879d45..ee7807b460c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4106.json
@@ -1 +1 @@
-{"BEOVU": 73.94804861967218, "DEXAMETHASONE": 15.033950482812074, "EYLEA": 480.1282698382223, "TOBRAMYCIN": 63.85817046197631, "null": 1.5236819929049794}
\ No newline at end of file
+{"null": 2.0317388645726813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4107.json
index 0fadd4f0ed1..79347b5641a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4107.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 3.150018199461718, "ASPARAGINASE": 7.198618205930351, "AUBAGIO": 3.759038421945805, "BUDESONIDE": 2.0737408933281296, "CICLOSPORIN": 2.313974468179848, "GARDASIL": 4.060867572764426, "JANUVIA": 3.015272438536037, "LEVETIRACETAM": 2.5758231206481925, "LYRICA": 2.718293052472552, "MELATONIN": 17.372796828632957, "OLANZAPINE": 2.223539220828348, "SHINGRIX": 1.8041336562813843, "null": 2.222396374569204}
\ No newline at end of file
+{"COMIRNATY": 0.9912405390020232, "GARDASIL": 11.833981075332511, "SPIKEVAX": 0.7890874018983999, "VAXZEVRIA": 0.9214939558972576, "null": 0.6199695260490775}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4108.json
index ecf889ac250..d6a060ab6fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4108.json
@@ -1 +1 @@
-{"AZILECT": 82.41361293303027, "BEXSERO": 61.32549657098565, "INFANRIX": 28.803101408203595, "MMRVAXPRO": 4.631635040947092, "NIMENRIX": 18.797493621394835, "PREVENAR": 33.332672706494805, "null": 1.8099637668189188}
\ No newline at end of file
+{"MMRVAXPRO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4109.json
index 9b7879232c0..1f61adeb21b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4109.json
@@ -1 +1 @@
-{"COMIRNATY": 1.936570070187534, "OMALIZUMAB": 5.218626617594258, "SPIKEVAX": 1.7878350330067785, "null": 1.0074698814532526}
\ No newline at end of file
+{"ABACAVIR": 0.7055481303631729, "ABILIFY": 1.9385494727300168, "AFINITOR": 0.8264576396501073, "ALEMTUZUMAB": 0.7548618588698164, "ALIMTA": 0.4727988877389305, "ALLI": 35.93279451767134, "AMIKACIN": 2.0985831552579417, "ARANESP": 0.6408117773618789, "ARAVA": 0.0402966571499281, "ASPARAGINASE": 4.697313980582321, "AVANDIA": 0.3314059882026504, "AXICABTAGENE": 20.69605486978968, "BEVACIZUMAB": 0.5200531756132398, "BRINTELLIX": 0.4790301491387351, "BUDESONIDE": 0.3373356199089226, "BUPIVACAINE": 1.1997178079878996, "BUPRENORPHINE": 0.5968921707403696, "BUSILVEX": 7.479959172991069, "BUSULFAN": 1.9507559876384064, "BYETTA": 0.3743193951825042, "CABOMETYX": 0.8625192206887987, "CANCIDAS": 5.113379632810168, "CAPECITABINE": 0.6361459379732948, "CELLCEPT": 2.8292743712965565, "CICLOSPORIN": 3.111035518377751, "COAPROVEL": 1.5272324384066842, "COMBIVIR": 1.4804966422992196, "COMIRNATY": 0.0900358465300991, "CUBICIN": 1.769046845591703, "CYMBALTA": 0.6989400406675741, "CYTARABINE": 3.1851358349031726, "DACLATASVIR": 9.29907867292176, "DAKLINZA": 4.7604117278802205, "DARZALEX": 2.022518263051156, "DEXAMETHASONE": 2.0026987228212128, "DOCETAXEL": 0.4988251061245317, "DOXORUBICIN": 1.8656015152048864, "DULOXETINE": 1.1300850747380178, "EFAVIRENZ": 1.78440049237074, "ELIQUIS": 0.3069906945131566, "EMEND": 35.7531092545134, "EPCLUSA": 3.036195173689428, "EPIVIR": 1.377653883399768, "EXJADE": 0.8942529280777703, "EXVIERA": 10.850321978614751, "FAMPRIDINE": 6.542838570896499, "FENTANYL": 1.4947224678054871, "FYCOMPA": 2.860885076501177, "GALVUS": 2.812879986650642, "GANCICLOVIR": 3.9401389606454673, "GARDASIL": 0.9237102351503528, "HARVONI": 4.8973122787396175, "HUMAN": 0.9781160575551526, "IBUPROFEN": 0.3239775519188463, "ICLUSIG": 1.1235117979176832, "INCIVO": 4.113972515939547, "INFANRIX": 2.25666709519876, "INLYTA": 0.462267723855799, "INVOKANA": 6.227337894992647, "IPILIMUMAB": 1.1964537341857109, "IRESSA": 0.7180867105890456, "ISENTRESS": 2.059363379723785, "JAKAVI": 0.399491830481376, "JANUVIA": 0.8700111514144727, "KALETRA": 1.489425733790916, "KEPPRA": 4.722780810784731, "KEYTRUDA": 1.1655127175398838, "KYMRIAH": 6.515280847963993, "KYPROLIS": 1.701756700048971, "LACOSAMIDE": 5.041979811322614, "LAMIVUDINE": 2.128890292933612, "LANTUS": 0.1759663217827585, "LENVIMA": 3.02890357611472, "LEVETIRACETAM": 3.5538455699192246, "LEVODOPA": 3.995185386549276, "LEVOFLOXACIN": 0.7419192085942989, "LYRICA": 1.2356679137410314, "MABTHERA": 1.5183664779504449, "MEKINIST": 1.142486320022036, "MELATONIN": 2.217035583181499, "METHOTREXATE": 1.1659893082790689, "MIDAZOLAM": 4.751134577615279, "MMRVAXPRO": 0.3515505406569649, "MYCOPHENOLATE": 1.166912882773525, "NEORECORMON": 17.58191376622502, "NEXAVAR": 3.0541839438948237, "NOT": 2.511557103640587, "NPLATE": 0.9985426579539302, "OBINUTUZUMAB": 3.36156516715479, "OCALIVA": 2.0511740424404508, "OLANZAPINE": 1.5107138589464024, "OLYSIO": 3.251525412656104, "OPDIVO": 0.7814298789302984, "OPSUMIT": 0.3920328695637993, "OXYBUTYNIN": 3.173506669922768, "PANTOPRAZOLE": 1.6414609411912375, "PEGASYS": 1.455350736958241, "PEGINTERFERON": 1.4042826787499183, "PEGINTRON": 2.280285349255256, "PLAVIX": 0.2197252591239742, "POSACONAZOLE": 11.507125946877672, "PREGABALIN": 2.890087745507574, "REBETOL": 2.1784189194327657, "REGORAFENIB": 9.23306606636068, "RIBAVIRIN": 3.523350458763207, "RISPERIDONE": 4.175079612766444, "RITUXIMAB": 0.6605626852484193, "ROACTEMRA": 0.4511401541816834, "SOLIRIS": 0.7761536994355326, "SOVALDI": 1.990843367542089, "SPIKEVAX": 0.1820907275027632, "STELARA": 0.2674871357990832, "STIVARGA": 1.9342952615861453, "SUBOXONE": 0.306839920430666, "SUTENT": 0.4494784386410562, "TACROLIMUS": 3.0534522890184603, "TAMIFLU": 5.498466830890743, "TELMISARTAN": 3.8846470810827474, "THALIDOMIDE": 1.859648398385881, "TISAGENLECLEUCEL": 28.856036376113, "TOZINAMERAN": 0.108856663012534, "TRUVADA": 0.0900987601650808, "VAXZEVRIA": 0.0341356387447739, "VFEND": 3.658346186714437, "VIAGRA": 0.3586638996263113, "VIGABATRIN": 20.375410411569156, "VIMPAT": 3.95509993170344, "VORICONAZOLE": 3.177670781034009, "VOTRIENT": 0.7744295531773513, "XTANDI": 0.4627037881344651, "YESCARTA": 27.64547330737424, "ZOSTAVAX": 0.3724992539877327, "ZYPREXA": 1.444870064384462, "null": 2.4082627176232165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/411.json
index 635eddd762b..cc50c49d956 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/411.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/411.json
@@ -1 +1 @@
-{"ADCIRCA": 14.896472493686606, "APROVEL": 11.413939234477873, "AVANDIA": 3.6539815259801465, "BUDESONIDE": 1.7181525230252337, "CICLOSPORIN": 3.7648758848386654, "CLOPIDOGREL": 1.5735249345262998, "ELIQUIS": 4.191937442985076, "HUMALOG": 3.5631461382820944, "JANUMET": 2.529347612870501, "LANTUS": 1.3989231513381897, "LYRICA": 2.050321555741438, "OMALIZUMAB": 4.402838179403826, "PEGASYS": 1.1961031728380358, "PEGINTRON": 1.9229350476312572, "PLAVIX": 2.783163353400479, "ROACTEMRA": 3.2738460299816365, "STELARA": 1.7992408898789665, "TRELEGY": 5.567259546844954, "VIAGRA": 6.2984258876672055, "ZOSTAVAX": 1.2129247235359482, "null": 1.5740470716721358}
\ No newline at end of file
+{"ARAVA": 1.3220517702315786, "CHAMPIX": 10.90144804920299, "PEGASYS": 6.55870769963997, "null": 2.185225904265113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4110.json
index 494e3b41ea1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4110.json
@@ -1 +1 @@
-{"KALETRA": 5.774242417544768, "KEPPRA": 4.90260679666417, "null": 7.868995535344396}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4111.json
index a9c2b13dec8..cb0e9061823 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4111.json
@@ -1 +1 @@
-{"null": 1.671936358066331}
\ No newline at end of file
+{"null": 2.048058036459657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4112.json
index 2a6c1ca3282..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4112.json
@@ -1 +1 @@
-{"null": 3.07919380766695}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4113.json
index f0d9682d119..109ef79acb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4113.json
@@ -1 +1 @@
-{"null": 6.78597621727484}
\ No newline at end of file
+{"null": 0.8215158129056229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4114.json
index ef14dadac20..290e055991a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4114.json
@@ -1 +1 @@
-{"ACLASTA": 1.2437955869135178, "ADCIRCA": 2.422629678754842, "ADEMPAS": 6.084273809446781, "ADENURIC": 1.2843509431031133, "AERIUS": 1.3266667573934667, "AFLIBERCEPT": 1.0114153484750006, "AMBRISENTAN": 2.117238389579711, "AMBROXOL": 12.83796113095845, "AMLODIPINE": 11.708560867906748, "ANGIOX": 3.67527228213373, "APROVEL": 5.17404812914473, "ARIXTRA": 1.3445315035900436, "ASENAPINE": 3.8470542251340887, "AXICABTAGENE": 1.3804612874517317, "AZILECT": 1.0169135028348684, "AZTREONAM": 1.9430692407723291, "BEDAQUILINE": 1.2233380466096575, "BENZODIAZEPINE": 1.632507030547132, "BENZODIAZEPINES": 3.061489714944795, "BEXTRA": 1.0136938904916326, "BINIMETINIB": 1.275521948695886, "BIVALIRUDIN": 5.902491779083089, "BLINDED": 8.32530415512522, "BOSENTAN": 1.275195837484461, "BRIDION": 7.282716285921468, "BUMETANIDE": 3.884213705071484, "BUPIVACAINE": 3.3459717183427045, "CAELYX": 1.7361049003564055, "CAFFEINE": 7.728082001329624, "CANGRELOR": 24.662597546329067, "CARBIDOPA": 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\ No newline at end of file
+{"null": 6.118191136968713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4115.json
index 1076c51c77a..ef5774e5dab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4115.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3860247284463578}
\ No newline at end of file
+{"ALEMTUZUMAB": 17.765386501231763, "ARANESP": 2.409788595944646, "ATRIPLA": 34.00940475203284, "AVANDIA": 2.847829702820295, "BUMETANIDE": 33.036327395440416, "CELLCEPT": 1.6545550085691931, "CICLOSPORIN": 4.215248372538579, "CLOPIDOGREL": 0.3000381607348, "COMIRNATY": 0.022298167927096, "CYMBALTA": 0.2050940270482952, "ELIQUIS": 0.4910443007644642, "ENTRESTO": 0.5565565188949565, "EXJADE": 0.5928253801840901, "HUMALOG": 1.940525636139066, "LANTUS": 1.0231596959990863, "LEVEMIR": 1.3973188126044511, "NORVIR": 2.6632980671724806, "NPLATE": 2.08161450725286, "OPSUMIT": 1.4564578640224433, "OPTIMARK": 2.0599429233168194, "PANTOPRAZOLE": 3.82400154753504, "RAPAMUNE": 2.715726517094673, "REVATIO": 1.6981025538671508, "SOLIRIS": 6.824515993377244, "SPIKEVAX": 0.0715783799390984, "STRIBILD": 13.156522103308722, "TRACLEER": 0.8126880313905486, "TRUVADA": 26.42406254763668, "VELTASSA": 7.336852987913095, "VIREAD": 34.05433917524757, "ZOSTAVAX": 0.3899869607278087, "null": 0.3864741088957372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4116.json
index df614970681..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4116.json
@@ -1 +1 @@
-{"null": 6.272130450456058}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4117.json
index 0c2db72a29f..696224926ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4117.json
@@ -1 +1 @@
-{"BUDESONIDE": 16.521413989303944, "HYDROCORTISONE": 137.89566713230414, "null": 3.086561168593964}
\ No newline at end of file
+{"FENTANYL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4118.json
index 2f54fc14d6f..550be2d6723 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4118.json
@@ -1 +1 @@
-{"IPILIMUMAB": 17.266786365829507, "KEYTRUDA": 33.390427184058176, "OPDIVO": 61.05255206910652, "YERVOY": 56.0289313002347, "null": 1.4737088377865808}
\ No newline at end of file
+{"FENTANYL": 52.47139714862501, "null": 1.8181522621922257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4119.json
index 1bd70be9646..8735cabbdbd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4119.json
@@ -1 +1 @@
-{"ABILIFY": 2.727639078176121, "ACTRAPID": 4.73765141438557, "ARIPIPRAZOLE": 1.5821772908513807, "BEDAQUILINE": 5.670450922014624, "BEXSERO": 13.4248188900688, "BRIDION": 5.1660197713440015, "BUPIVACAINE": 2.909448883283917, "DULOXETINE": 1.7026606035321132, "EUCREAS": 7.131139310790509, "FENTANYL": 3.547473153398565, "FLEBOGAMMA": 3.83884042865582, "FYCOMPA": 11.451326894691636, "IBUPROFEN": 1.0859991825270685, "KEPPRA": 3.330552349857597, "KYMRIAH": 1.59266102512166, "LANTUS": 1.6638603551675335, "LEVEMIR": 1.452856102185237, "LEVETIRACETAM": 1.277760969005875, "LEVODOPA": 8.659507732707416, "LYRICA": 1.3484361006013397, "MIDAZOLAM": 3.0011687092186925, "MMRVAXPRO": 1.630564052320442, "OLANZAPINE": 7.957704254517482, "PREGABALIN": 2.254572635668405, "PRIVIGEN": 2.376735416412435, "RISPERIDONE": 4.774712848697141, "TAMIFLU": 13.519531127114258, "ZYPREXA": 4.182162221453252, "null": 2.33410298962818}
\ No newline at end of file
+{"FENTANYL": 225.22128790243488, "null": 0.9518920967503458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/412.json
index d67a8cae467..87adc83f5bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/412.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/412.json
@@ -1 +1 @@
-{"null": 1.070213856071489}
\ No newline at end of file
+{"null": 0.8565727309887768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4120.json
index 82fe5841fc7..69c56bd195b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4120.json
@@ -1 +1 @@
-{"null": 2.4815607600334006}
\ No newline at end of file
+{"OPSUMIT": 55.19375759302782, "TRACLEER": 70.75848955340513, "null": 0.5026955502585587}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4121.json
index 71ff512b168..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4121.json
@@ -1 +1 @@
-{"null": 2.762913163152542}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4122.json
index 1707f4c8c42..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4122.json
@@ -1 +1 @@
-{"ABILIFY": 4.175130506125828, "ACLIDINIUM": 2.0899723832883224, "AFINITOR": 1.0844077936151262, "ALEMTUZUMAB": 1.7600791017415809, "AMINOSALICYLIC": 2.7019249988418075, "ANORO": 18.002388832965554, "APIXABAN": 18.169311126462624, "ARIPIPRAZOLE": 1.4095562443125864, "ATEZOLIZUMAB": 5.28004628499475, "AVELUMAB": 30.30551508517025, "AVONEX": 3.589389630015726, "AXITINIB": 27.577781786180037, "AZATHIOPRINE": 1.5476461773386891, "BAVENCIO": 41.53422504399764, "BETAFERON": 1.043551861108633, "BRAFTOVI": 1.2911330994239971, "BYDUREON": 1.0688091818065124, "BYETTA": 2.9668120296031213, "CABOMETYX": 28.96744611916492, "CARMUSTINE": 1.1862846021400446, "DELAMANID": 4.614435957586953, "EPADERM": 38.0176560464381, "ERLEADA": 9.61074919584059, "ESOMEPRAZOLE": 1.6504260995802569, "EVEROLIMUS": 3.953510726380879, "FASLODEX": 1.0821481968812852, "FOTIVDA": 9.370291237474746, "HUMIRA": 1.016388258469894, "ICLUSIG": 1.804502573032024, "INLYTA": 12.046258491430343, "INTERFERON": 9.94358682446966, "INTRONA": 8.604319828204773, "IPILIMUMAB": 13.434881726666614, "JANUMET": 1.288587802469823, "JANUVIA": 1.2052086283144234, "KEYTRUDA": 32.01013841738435, "LEMTRADA": 8.927005992463785, "LENVIMA": 18.639165602739286, "LIBTAYO": 16.56030425450857, "LIRAGLUTIDE": 47.69135187261906, "LYSODREN": 7.792186168294314, "MAVENCLAD": 1.357012861426595, "METFORMIN": 3.5956081282438097, "MITOTANE": 12.78136320557146, "NEXAVAR": 1.7255361596604233, "NILOTINIB": 1.3228742526122073, "NIVOLUMAB": 9.037974754439654, "OCEAN": 23.937833835471064, "OPDIVO": 19.828938271863997, "PACLITAXEL": 2.3342781242198027, "PAZOPANIB": 7.411496511870068, "PEGASYS": 5.313897539842043, "PEGINTERFERON": 2.484518463119456, "PEGINTRON": 5.864273946906122, "PEMBROLIZUMAB": 16.805180227366627, "PROPRANOLOL": 1.4605853674488474, "REBETOL": 4.474055923788559, "REGORAFENIB": 5.385802107028406, "RIBAVIRIN": 1.064246401715855, "RISPERIDONE": 1.0267117058834736, "SOMATROPIN": 1.5047748803994403, "SORAFENIB": 1.8625152058657672, "STIVARGA": 4.873288170592558, "SUNITINIB": 18.01285600587825, "SUTENT": 8.881466818030372, "TASIGNA": 1.234809087242965, "VOTRIENT": 4.472125644502695, "YERVOY": 5.031543586318606, "ZOSTAVAX": 3.5631229431851064}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4123.json
index b7c5bce5b9e..1825b2ce5f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4123.json
@@ -1 +1 @@
-{"BEXSERO": 11.735787655751778, "BRIDION": 2.6330147698831903, "COMBIVIR": 3.1492794709685703, "COMIRNATY": 1.3244675139718314, "DEXMEDETOMIDINE": 8.258811560657222, "DULOXETINE": 1.152397150875641, "ENTRESTO": 1.138792460351556, "EPIVIR": 1.5222867412172605, "FAMPYRA": 1.2371519684058243, "FYCOMPA": 2.877735763930547, "GARDASIL": 2.1086709497718603, "GENERAL": 38.236220074488855, "HEXYON": 14.955513028298991, "INFANRIX": 29.24185632867904, "INVIRASE": 7.923019980290586, "KEPPRA": 2.408479151492726, "LEVETIRACETAM": 3.652039108564368, "MENVEO": 4.567090848444231, "MIDAZOLAM": 2.682739318414337, "MMRVAXPRO": 4.534406081600937, "NAGLAZYME": 2.275604655989829, "NIMENRIX": 2.367011009428384, "NOT": 4.338967905265661, "OLANZAPINE": 1.372835357515606, "PREVENAR": 13.220615682185338, "ROTARIX": 49.32683900561248, "ROTATEQ": 8.508433263001, "SHINGRIX": 1.454210489975014, "SPIKEVAX": 1.034087173985229, "SPINRAZA": 2.3214445971719915, "SUFENTANIL": 3.034198419847066, "SYNAGIS": 4.365242659348025, "SYNFLORIX": 15.496026164217271, "TWINRIX": 1.8424582866577537, "VALSARTAN": 5.939150000865812, "VAXZEVRIA": 2.7827117143086797, "ZYPADHERA": 3.0019890175146755, "null": 1.683735603051295}
\ No newline at end of file
+{"null": 3.016159131874084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4124.json
index 51f5d98c785..85ec5d90f71 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4124.json
@@ -1 +1 @@
-{"FENTANYL": 5.272014947658747, "KEPPRA": 5.599414634373877, "LEVETIRACETAM": 12.020981570990903, "OLANZAPINE": 5.8236503102731785, "ZYPREXA": 8.021537254859577, "null": 7.266012887858744}
\ No newline at end of file
+{"OPTIMARK": 198.569371909976, "null": 0.800415278061176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4125.json
index d0134167ba1..6d798e69ba7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4125.json
@@ -1 +1 @@
-{"TOVIAZ": 167.9625798856184, "null": 1.1821588320254246}
\ No newline at end of file
+{"ARAVA": 0.2136707902986784, "BUPRENORPHINE": 7.649005133574212, "CELLCEPT": 5.696093826942959, "CICLOSPORIN": 2.929448685258107, "COMIRNATY": 0.3518389203538908, "CUBICIN": 54.16991503955047, "DAPTOMYCIN": 66.15875443104805, "DEXAMETHASONE": 1.7311371937615272, "ELIQUIS": 1.4036664617409185, "FENTANYL": 1.7224361686919647, "FORXIGA": 2.9502287931557576, "JARDIANCE": 1.1817881408280475, "KEYTRUDA": 1.4640941566553858, "METHOTREXATE": 2.207009587256098, "OPSUMIT": 1.3826089942065944, "PEGASYS": 3.8035423732818976, "PEGINTRON": 1.2207846623530478, "RITUXIMAB": 2.149026242120611, "ROACTEMRA": 7.1146791038741934, "SIMPONI": 2.3135143467766723, "SOLIRIS": 5.166882071605969, "SPIKEVAX": 0.2379748530539038, "STELARA": 1.5901360657560764, "SUBOXONE": 7.489962753352056, "TOZINAMERAN": 0.343863214901491, "TRACLEER": 2.3131091085449773, "VAXZEVRIA": 0.0867195563362584, "null": 1.1907866611000817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4126.json
index 604b65a64f3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4126.json
@@ -1 +1 @@
-{"BEXSERO": 80.07405606071534, "COMIRNATY": 1.5649407380756148, "GARDASIL": 1.121398815092004, "HEXACIMA": 271.509093342318, "HEXYON": 100.34455324278557, "INFANRIX": 338.5070124109697, "MMRVAXPRO": 36.14993408742078, "NIMENRIX": 11.353942900704736, "NOT": 20.812459476653828, "PREVENAR": 61.33236573240623, "ROTARIX": 158.4509413574325, "ROTATEQ": 34.30344988437864, "SYNFLORIX": 157.4062306832819, "null": 1.0443228655737755}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4127.json
index 3581e5abe41..40b4998b537 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4127.json
@@ -1 +1 @@
-{"EYLEA": 193.76085333873388, "null": 2.203448711752774}
\ No newline at end of file
+{"PEGASYS": 3.966557141860426, "null": 0.8576291823867606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4128.json
index 688cb33943d..334c4bd06a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4128.json
@@ -1 +1 @@
-{"null": 2.0301784492250383}
\ No newline at end of file
+{"null": 0.8340297510290067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4129.json
index a312cf12816..96874e7c1f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4129.json
@@ -1 +1 @@
-{"BUSULFAN": 40.73581760421237, "HEPSERA": 1112.684669710175}
\ No newline at end of file
+{"OSELTAMIVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/413.json
index 14280e53bd2..d529f80d485 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/413.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/413.json
@@ -1 +1 @@
-{"ELIQUIS": 8.138587077294591, "FORXIGA": 12.850542403650108, "null": 1.0269022999227289}
\ No newline at end of file
+{"OLANZAPINE": 15.002089100367453, "SUBOXONE": 13.517819895565216, "ZYPREXA": 8.77376466562783, "null": 1.7652963646475677}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4130.json
index 3f1b72b2807..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4130.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 4.25043684137485, "BRIDION": 65.10665512450535, "BUDESONIDE": 1.1435035032029002, "DEXAMETHASONE": 3.932546430844932, "FENTANYL": 15.435268910019031, "LACOSAMIDE": 6.940039891958013, "MIDAZOLAM": 31.46992846166537, "NUCALA": 5.318175688124239, "OLANZAPINE": 4.83560549183394, "OMALIZUMAB": 26.953863335182177, "XOLAIR": 9.901946952078251, "ZYPREXA": 2.681014305037764, "null": 2.085488309373476}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4131.json
index d0efa013ffd..6879e455af4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4131.json
@@ -1 +1 @@
-{"null": 2.154150020697041}
\ No newline at end of file
+{"ELIQUIS": 21.83168615919631}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4132.json
index b820200aa8f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4132.json
@@ -1 +1 @@
-{"ATRIPLA": 1.4821676922751577, "KEPPRA": 4.322584251932325, "ZOSTAVAX": 5.982363152033486, "null": 1.966777499584661}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4133.json
index f25dbf5f111..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4133.json
@@ -1 +1 @@
-{"ADCIRCA": 10.658654492853346, "ARIPIPRAZOLE": 2.527935899172644, "BUDESONIDE": 5.967726970506194, "BUMETANIDE": 61.97871648184076, "BYETTA": 2.153618768855323, "DEXAMETHASONE": 2.575047791369834, "EMPAGLIFLOZIN": 68.58981438559384, "ENALAPRIL": 71.48626663745546, "ENTRESTO": 6.750063890942708, "FENTANYL": 1.4805124721350198, "FORXIGA": 5.053126299056451, "IBUPROFEN": 1.9108369931488345, "IRBESARTAN": 4.608087195934704, "JANUMET": 2.607602963249857, "JANUVIA": 3.4722612878907597, "JARDIANCE": 12.50705097525911, "MICARDIS": 3.90426144568914, "PEGINTERFERON": 2.757941523948967, "PEGINTRON": 1.8132318772824751, "PREGABALIN": 3.4382222589754106, "ROTATEQ": 3.5095967220087267, "SPIRONOLACTONE": 15.800302349654713, "null": 2.023729014112016}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4134.json
index b4c586d7f5e..40c69d74ccf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4134.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 3.476290496637614, "CLOPIDOGREL": 3.711692640599576, "COAPROVEL": 7.784462777975893, "CYTARABINE": 1.8537072328777675, "ELIQUIS": 2.744189813199186, "ENOXAPARIN": 22.157071704608715, "ENTRESTO": 2.0526053614482795, "FENTANYL": 1.638000067120729, "JARDIANCE": 2.6678334283396348, "LEVOFLOXACIN": 3.105191578016871, "MIDAZOLAM": 5.578067120436186, "NOVOSEVEN": 27.48841974177974, "OPSUMIT": 1.489049594523149, "PLAVIX": 5.373140518859981, "TOZINAMERAN": 1.4904266799457353, "XARELTO": 18.02064426702114, "null": 1.7289190098284517}
\ No newline at end of file
+{"CUBICIN": 303.4296897289892, "null": 1.60620466158052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4135.json
index 6dc341d27d5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4135.json
@@ -1 +1 @@
-{"ABRAXANE": 2.816162523260792, "ADCIRCA": 6.086202415632863, "ADEMPAS": 3.897665608226816, "AFINITOR": 2.075621553182282, "ALEMTUZUMAB": 1.4492426117674957, "AMBRISENTAN": 3.4917185393993955, "AMIKACIN": 4.797577679130017, "ANORO": 29.450185681376823, "APIXABAN": 5.007494141037422, "APREPITANT": 3.6506345400712936, "ASPARAGINASE": 1.7045552983841716, "AZACITIDINE": 1.7720009754355193, "AZATHIOPRINE": 2.29469075456051, "BORTEZOMIB": 1.0706473222801642, "BRIDION": 11.732621449064451, "BUDESONIDE": 3.898813490122389, "BUPIVACAINE": 3.679595413361564, "BUPRENORPHINE": 1.259835200654655, "BUSULFAN": 1.8707342703842376, "CAELYX": 2.9732175357673745, "CANCIDAS": 1.4635999774643649, "CASPOFUNGIN": 3.275082463322547, "CELLCEPT": 1.6268164847405546, "CICLOSPORIN": 1.8157388374071084, "CUBICIN": 6.578677513883645, "CYTARABINE": 3.356690480536494, "DAPTOMYCIN": 3.7053771029911298, "DARZALEX": 3.8504608357566528, "DEXAMETHASONE": 3.3513604497961764, "DEXMEDETOMIDINE": 7.118176340894656, "DOXORUBICIN": 5.066251683724025, "ENOXAPARIN": 1.8423275185468693, "ESBRIET": 3.453480625970981, "EVEROLIMUS": 3.7770093858823537, "FASENRA": 1.4978110111815397, "FENTANYL": 5.541835219371921, "FILGRASTIM": 3.470708117776895, "FIRDAPSE": 2.549474865649298, "FLEBOGAMMA": 7.254197857739967, "GANCICLOVIR": 4.639274883002148, "GAZYVARO": 2.6807289258052616, "HERCEPTIN": 1.0302415237976863, "HUMAN": 3.014060738086456, "HYDROCORTISONE": 1.0825696475682522, "IBUPROFEN": 1.783186812356301, "INSULIN": 1.055542292259943, "IRBESARTAN": 1.551957625411034, "IRESSA": 1.966710712547991, "JAKAVI": 1.4860596951157512, "KIOVIG": 2.669461542959915, "KYMRIAH": 16.491645778492636, "LAMIVUDINE": 1.0063366031408056, "LEVOFLOXACIN": 1.264136427431495, "MACITENTAN": 4.651527694551911, "MELPHALAN": 3.2047242109656606, "MIDAZOLAM": 7.946184836165208, "MULTAQ": 1.2856876923061284, "MYCOPHENOLATE": 1.4388612944230024, "NAGLAZYME": 1.9352514070881977, "NALOXONE": 6.211441553980293, "NIVOLUMAB": 6.673028803452018, "NPLATE": 1.1114780416128387, "NUCALA": 1.5130515995938365, "OCEAN": 36.494907587940936, "OFEV": 2.2809805020470924, "ONCASPAR": 3.025177610049864, "OPSUMIT": 9.636424373122932, "OSELTAMIVIR": 8.192240618259053, "PACLITAXEL": 2.2256927357535754, "PIRFENIDONE": 4.280869916629347, "PRADAXA": 3.257346062597755, "PRIVIGEN": 7.532469597979104, "QARZIBA": 7.0618813113374905, "RASBURICASE": 45.70352594967808, "REMDESIVIR": 11.119021530987798, "REVATIO": 6.579613087608645, "RISPERIDONE": 3.931237559423455, "RITUXIMAB": 1.169864277173075, "SILDENAFIL": 4.075372613822369, "SOLIRIS": 1.0587333754489805, "SPINRAZA": 2.6077343636746, "SUFENTANIL": 4.237604610999548, "SYNAGIS": 8.17891716182334, "TAMIFLU": 2.0473521077900894, "TISAGENLECLEUCEL": 17.688184690083133, "TOCILIZUMAB": 2.793792458103257, "TRACLEER": 10.650307872178091, "TRACTOCILE": 15.243559350458913, "TRELEGY": 1.4591535967078904, "VEKLURY": 5.687383023688201, "VORICONAZOLE": 1.3970747130968075, "XALKORI": 1.5781018496647492, "YESCARTA": 8.396987476281254, "ZIAGEN": 5.229033669015095, "ZYPREXA": 1.167905960919598, "null": 1.5513347018401875}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4136.json
index dfdfb771c7e..e75cfa7c9f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4136.json
@@ -1 +1 @@
-{"ABILIFY": 10.157120966813215, "AVANDIA": 11.517689810883622, "BRIDION": 19.799852917211773, "CUBICIN": 19.176477140611063, "DEXAMETHASONE": 2.746147720263091, "FENTANYL": 10.731963761292471, "GLUCAGON": 87.4524883122731, "KEPPRA": 1.4361046961253674, "MIDAZOLAM": 13.915744659229526, "OLANZAPINE": 3.42564366408953, "ZYPREXA": 3.288391837224776, "null": 2.135755002766772}
\ No newline at end of file
+{"COMIRNATY": 0.3198330398465907, "IPILIMUMAB": 34.18757059239579, "KEYTRUDA": 9.52534947040808, "OPDIVO": 19.05909630543023, "TOZINAMERAN": 0.7619480918469569, "YERVOY": 46.589106690286464, "null": 1.222647379696854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4137.json
index 8a9942bece3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4137.json
@@ -1 +1 @@
-{"null": 7.408067933199498}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4138.json
index 6f89672fcbb..425edd19760 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4138.json
@@ -1 +1 @@
-{"AUBAGIO": 5.032185795308699, "BENLYSTA": 7.131662929342876, "BUDESONIDE": 3.5367053072578023, "BYETTA": 12.624110253195848, "CIMZIA": 2.631512360634101, "CYMBALTA": 4.823055032938819, "HUMIRA": 2.8364282911160057, "IBRANCE": 3.050273152921164, "JANUMET": 21.341633079720545, "JANUVIA": 16.49436088771977, "JARDIANCE": 1.2629310457177232, "METHOTREXATE": 5.848384042759211, "OPSUMIT": 3.969902988576408, "RUCONEST": 22.422541020961425, "SIMPONI": 5.393138011817516, "STELARA": 5.71035751410505, "TREMFYA": 6.457031983092547, "XELJANZ": 1.852144343759512, "ZOSTAVAX": 9.396643114649471, "ZYPREXA": 1.4307792764452116, "null": 1.187120549099582}
\ No newline at end of file
+{"null": 0.9518920967503458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4139.json
index 7292bc6f289..bafbcc979b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4139.json
@@ -1 +1 @@
-{"null": 5.172121072992665}
\ No newline at end of file
+{"ALEMTUZUMAB": 33.568295375885285, "ARAVA": 6.369799322648385, "COMIRNATY": 1.055214867733762, "LEMTRADA": 63.31984974641683, "SPIKEVAX": 0.8724919846594886, "TOZINAMERAN": 2.5311974833088304, "VAXZEVRIA": 0.245074726572711, "null": 0.3577223209266657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/414.json
index e0cb2042f5c..01098349077 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/414.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/414.json
@@ -1 +1 @@
-{"ABILIFY": 4.138060861153133, "AERIUS": 1.8345508552658765, "BRINTELLIX": 4.9298653301322455, "BRIVARACETAM": 8.412027317854058, "BRIVIACT": 14.593799580341882, "CHAMPIX": 24.215432472450004, "CYMBALTA": 8.668178873620828, "DULOXETINE": 1.962129225610948, "EXFORGE": 1.308833231272926, "FYCOMPA": 25.77277814290632, "HARVONI": 2.0121463620690245, "INCIVO": 1.1013214453710425, "INTUNIV": 65.12814380348618, "KAFTRIO": 7.849411130282721, "KEPPRA": 11.92436980786837, "LATUDA": 13.500701450748942, "LEVETIRACETAM": 5.159217232548572, "LYRICA": 2.8832334185879467, "MIDAZOLAM": 1.3023882984476178, "OLANZAPINE": 1.289096648263547, "PEGASYS": 4.828531391228215, "PEGINTRON": 3.96912224177088, "PERAMPANEL": 33.01116502743489, "PLEGRIDY": 1.3166113501454786, "PREGABALIN": 3.967795546441717, "RIBAVIRIN": 1.3132255400685613, "SUBOXONE": 2.001304033547267, "TESTOSTERONE": 5.4076833385033, "VARENICLINE": 9.479165282595376, "VIMPAT": 3.642161823997201, "XYREM": 2.2570229130518658, "ZYPREXA": 2.424903205000438, "null": 2.37083254902094}
\ No newline at end of file
+{"null": 1.2825526105920724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4140.json
index 5d7d6d7813a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4140.json
@@ -1 +1 @@
-{"COMIRNATY": 1.050128986796682, "TOZINAMERAN": 1.5080148085790464}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4141.json
index db604f3ecdf..b8a9582b785 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4141.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2798657391530737, "null": 1.5257893909976403}
\ No newline at end of file
+{"ANAKINRA": 55.83682576514275, "ARAVA": 1.4231075695286275, "IBRANCE": 5.626417478185196, "PEGASYS": 3.844208586611816, "SIMPONI": 9.25724806296796, "null": 1.227073622611793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4142.json
index 5deb603166f..3017cc704f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4142.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1766997005033666, "TOZINAMERAN": 2.636116327406363}
\ No newline at end of file
+{"COMIRNATY": 1.9165846735431091, "null": 0.2856046929218559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4143.json
index 2e801746d9f..f3973051fd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4143.json
@@ -1 +1 @@
-{"null": 2.59678681761694}
\ No newline at end of file
+{"ESMYA": 131.67294194371905, "EVISTA": 603.9414079145375, "null": 0.884048978678697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4144.json
index caf2a0d2872..cd57cca0d5f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4144.json
@@ -1 +1 @@
-{"ICLUSIG": 224.17622711282465, "METHOTREXATE": 37.07500869439725}
\ No newline at end of file
+{"FORSTEO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4145.json
index 6ea09c5d1a2..928345c2e05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4145.json
@@ -1 +1 @@
-{"ICLUSIG": 216.95484361890703}
\ No newline at end of file
+{"null": 1.3727476869860695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4146.json
index 4f67fe2c4c1..dba044d3835 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4146.json
@@ -1 +1 @@
-{"null": 2.7893707053248438}
\ No newline at end of file
+{"ESMYA": 60.53331518222216, "EVISTA": 231.6020401367057, "LANTUS": 1.359779169984851, "STELARA": 4.7464027139728815, "TESTOSTERONE": 45.62416534941225, "TREMFYA": 25.995582423225635, "XELJANZ": 2.7478744826188293, "null": 1.539978507068292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4147.json
index e4c79db2f63..8a75066dc02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4147.json
@@ -1 +1 @@
-{"null": 1.0019793231953782}
\ No newline at end of file
+{"null": 1.2991879801778887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4148.json
index d0201d89f85..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4148.json
@@ -1 +1 @@
-{"ELIQUIS": 9.396406832254192, "null": 1.1751565399393764}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4149.json
index de021c983ae..16d9964df94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4149.json
@@ -1 +1 @@
-{"CICLOSPORIN": 5.417700424104092, "GARDASIL": 4.383536482427187, "KAFTRIO": 20.23402519496648, "SOMATROPIN": 241.6653602346964, "STELARA": 2.6763360230973765, "TESTOSTERONE": 65.82142776256607, "ZYPREXA": 1.7149927601706536, "null": 2.704367944583116}
\ No newline at end of file
+{"null": 1.191905231702337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/415.json
index 830cd4780de..14251a07b6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/415.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/415.json
@@ -1 +1 @@
-{"ACTOS": 1.1758330704018345, "ADCIRCA": 5.8131658178941805, "ALISKIREN": 20.746562321922468, "APROVEL": 1.690048553997339, "AVANDAMET": 12.503593489808305, "AVANDIA": 10.07954079592127, "BETAFERON": 1.1973600793264272, "BRILIQUE": 5.597011332411711, "CAPECITABINE": 1.493324603129425, "CHAMPIX": 2.283953208187737, "CLOPIDOGREL": 3.493836686260948, "COAPROVEL": 1.0953867788845035, "COMBIVIR": 1.2563308239538375, "COMIRNATY": 1.7597801743159194, "COMPRESSION": 47.49339020417307, "CRIXIVAN": 1.327346192186044, "DULOXETINE": 2.3807514556505818, "EFIENT": 7.759070931834747, "ENTRESTO": 1.7384238953779805, "EPADERM": 43.61989143589956, "EPIVIR": 1.0439428412680325, "ESOMEPRAZOLE": 1.6236914488928982, "EVENITY": 5.096299573872878, "EXFORGE": 2.862233653237765, "FEBUXOSTAT": 3.3446336817222884, "FORSTEO": 1.789678203092723, "GLIBENCLAMIDE": 2.21251521654856, "ICLUSIG": 2.5644106512476155, "INFLIXIMAB": 1.1922578834926945, "INSULIN": 4.273126204683987, "IVABRADINE": 25.267803954709017, "KYPROLIS": 2.0262142518999027, "LANTUS": 1.4690518432398665, "MEPOLIZUMAB": 1.7409144104168432, "MICARDIS": 2.0719069499589384, "MIXTARD": 3.6450654210813416, "MULTAQ": 1.3809324788890422, "NILOTINIB": 4.542590492063399, "NOVOSEVEN": 1.3783734559680292, "PLAVIX": 4.223473972436615, "RANEXA": 8.825517861269901, "RANOLAZINE": 18.4296308397781, "RAPISCAN": 9.12085758322994, "RASILEZ": 2.3125374202489866, "RELVAR": 1.6473028290909166, "RIVAROXABAN": 4.64321205926022, "SILDENAFIL": 1.6550623540361875, "SPIKEVAX": 1.0641961543791938, "STALEVO": 1.1150691682388123, "TASIGNA": 6.4167786430618, "TESTOSTERONE": 2.9020354193847595, "TICAGRELOR": 1.4384302679760557, "TIVICAY": 1.4903921997272145, "TOZINAMERAN": 1.638010912109612, "TRELEGY": 1.3007884020038962, "VIAGRA": 2.8959427574340846, "XELODA": 2.2384108583098943, "ZYLLT": 15.01791663778948}
\ No newline at end of file
+{"BRIVIACT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4150.json
index 071c1c1a06d..f455d147da2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4150.json
@@ -1 +1 @@
-{"BROLUCIZUMAB": 2660.372760591177}
\ No newline at end of file
+{"COMIRNATY": 0.2723989567876608, "null": 3.57600800013991}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4151.json
index 0b78654f317..ca5612b21b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4151.json
@@ -1 +1 @@
-{"BUSULFAN": 163.27742089422068, "CICLOSPORIN": 45.1671712987872}
\ No newline at end of file
+{"COMIRNATY": 0.2515701969483159, "ESMYA": 449.8768029927492, "EVISTA": 133.56486836752222, "null": 2.2989027205484787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4152.json
index 370b35c666b..caf79ef26f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4152.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.5368532978281173, "ESBRIET": 159.16530838165005, "OFEV": 650.3447195237708, "OPSUMIT": 2.911343106628782, "PIRFENIDONE": 166.8642218539805}
\ No newline at end of file
+{"null": 1.4595297982745308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4153.json
index 3dc397b7905..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4153.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.1609202877384563, "XOLAIR": 24.82710464781455}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4154.json
index be2796885da..2626bc15737 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4154.json
@@ -1 +1 @@
-{"null": 3.752291490910505}
\ No newline at end of file
+{"VOTRIENT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4155.json
index cea2617bc7a..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4155.json
@@ -1 +1 @@
-{"CELLCEPT": 8.20504393231869, "CICLOSPORIN": 4.513350701188741, "KEYTRUDA": 1.5846954123610062, "REMICADE": 23.9725461664861, "SIMPONI": 5.703988591736264, "SPIKEVAX": 1.655528583868353, "STELARA": 9.598885732283458, "TOZINAMERAN": 2.412441890747129}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4156.json
index 6d90dc0a7c2..440865c15f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4156.json
@@ -1 +1 @@
-{"AVASTIN": 97.7315004757852, "IBUPROFEN": 16.457301471061623}
\ No newline at end of file
+{"VOTRIENT": 134.39772500777065}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4157.json
index f16636c0c1d..7168bba5689 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4157.json
@@ -1 +1 @@
-{"ADALIMUMAB": 4.054272166894666, "CIMZIA": 11.303376972032016, "ENTYVIO": 79.9316154158349, "STELARA": 38.1496453799906}
\ No newline at end of file
+{"COMIRNATY": 0.3452580169445504, "ESMYA": 694.6384135973799, "null": 2.14273640845998}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4158.json
index 9ef9c52bb04..4f81e70903b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4158.json
@@ -1 +1 @@
-{"ABACAVIR": 9.03149706490749, "null": 1.7020725844608953}
\ No newline at end of file
+{"AIMOVIG": 1.589819796285964, "AMINOSALICYLIC": 3.562227234659592, "BOTULINUM": 13.40698224446131, "CIMZIA": 1.6831931630424823, "COMIRNATY": 3.166509117157225, "COSENTYX": 2.553011241533464, "FENTANYL": 2.1279966119809424, "GARDASIL": 7.821178586733486, "LYRICA": 3.9065518114704, "MODERNA": 3.361286785043206, "SPIKEVAX": 0.8755427919626587, "STELARA": 3.241757077383356, "TOZINAMERAN": 2.464873320203884, "VAXZEVRIA": 0.4365942244584205, "null": 0.492864459512885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4159.json
index c5e09a803c6..01985268f6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4159.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 127.64466264750872}
\ No newline at end of file
+{"IBUPROFEN": 36.744256841442905, "STELARA": 7.618320442302831, "null": 2.790565814045662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/416.json
index 17e315749cd..24241a6843e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/416.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/416.json
@@ -1 +1 @@
-{"ADENURIC": 15.484833348324916, "AVANDAMET": 100.22710915779828, "AVANDIA": 77.83761588051956, "BRILIQUE": 10.93581089931697, "CHAMPIX": 1.1462188915967515, "CLOPIDOGREL": 4.950995703904378, "COMBIVIR": 5.191448261231964, "EFIENT": 30.02469311537381, "ICLUSIG": 7.074902856258915, "INVIRASE": 31.72654167313184, "IVABRADINE": 41.09930766440105, "MICARDIS": 2.4281032381504866, "NEXAVAR": 1.093667211924092, "NOT": 4.239119553640717, "PLAVIX": 8.81379350964742, "TASIGNA": 5.935670670071813, "TICAGRELOR": 5.615154263583051, "TRELEGY": 3.223128884475833, "ZYPREXA": 1.3462044050161337, "null": 1.1797952657952058}
\ No newline at end of file
+{"null": 1.4853773445371572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4160.json
index dd0d273b939..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4160.json
@@ -1 +1 @@
-{"CIMZIA": 10.683392951223796, "ENTYVIO": 14.753470634160829, "HUMIRA": 15.658315811925988, "RINVOQ": 45.64470545883065, "STELARA": 20.803512751705878, "XELJANZ": 7.214297757967563}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4161.json
index 89ab7643b87..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4161.json
@@ -1 +1 @@
-{"ABILIFY": 1.1217668534041445, "AFINITOR": 1.807725129318551, "AIMOVIG": 2.2143310170188677, "ALIMTA": 2.156734372783618, "ARIPIPRAZOLE": 1.980515054696536, "ASPARAGINASE": 4.122709627905447, "AVASTIN": 10.860033995943873, "BEVACIZUMAB": 6.410873255619391, "BRAFTOVI": 5.136208007165405, "BYETTA": 2.82373570948684, "CABOMETYX": 2.129745645934271, "CAPECITABINE": 2.1972984756670977, "CELLCEPT": 3.608336993972476, "CHAMPIX": 2.1735371155199514, "COMTAN": 5.105548748995882, "CRIZOTINIB": 43.906279563289374, "CYTARABINE": 2.274358284995789, "DEXAMETHASONE": 1.4110421227071956, "EMTRIVA": 27.70636651902821, "ENTYVIO": 1.2941945612496617, "FENTANYL": 2.458098054895996, "GLUCAGON": 40.15298729404237, "HYCAMTIN": 10.828623647493885, "IBUPROFEN": 1.116543242657076, "INLYTA": 1.2532088288440602, "INSULIN": 1.1685328609283865, "IRESSA": 4.679579289264152, "JAKAVI": 1.0832524833043768, "JANUMET": 1.5226836207640628, "JANUVIA": 4.968120112268087, "JEVTANA": 9.83694704904808, "KALETRA": 1.3489062817355757, "KEPPRA": 1.6882721819130475, "KEYTRUDA": 3.3916147041408395, "LACOSAMIDE": 2.825157680906482, "LYNPARZA": 14.340973853391326, "LYRICA": 1.3232435189838825, "MIDAZOLAM": 1.9093237113598407, "NOXAFIL": 4.532827050205031, "OLANZAPINE": 1.955000882332209, "OPDIVO": 1.8322900459478892, "REMICADE": 3.524663454743522, "ROTATEQ": 3.563286202626382, "SAXENDA": 1.7500581851225605, "STALEVO": 6.712852956988915, "STELARA": 1.758959558222466, "STIVARGA": 5.109396343139419, "TAMIFLU": 1.9841066805506535, "TOVIAZ": 3.5806682207386484, "TRULICITY": 3.914229888618311, "VFEND": 1.9337936582833488, "VICTOZA": 2.059842546515042, "XELODA": 5.047902978645126, "ZYPREXA": 2.752931906856737, "null": 1.74891630372341}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4162.json
index 32fc0124064..a20856bc4e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4162.json
@@ -1 +1 @@
-{"AIMOVIG": 2.6753985625393493, "ASPARAGINASE": 9.51751603334407, "BORTEZOMIB": 8.055542746336965, "CELLCEPT": 2.5204144742580685, "DEXAMETHASONE": 2.350763621930446, "DOCETAXEL": 6.388616230068829, "FENTANYL": 1.820773699683934, "KALETRA": 5.4228912935829765, "KEPPRA": 2.813218186823406, "KEYTRUDA": 1.2667207501708786, "METHOTREXATE": 1.6329978285144848, "MIDAZOLAM": 7.676027778333676, "NOXAFIL": 11.322323292353287, "OLANZAPINE": 8.155465312920613, "POSACONAZOLE": 19.061689494692185, "VICTOZA": 2.955113419600842, "ZYPREXA": 4.308669342203076, "null": 2.8170180141291388}
\ No newline at end of file
+{"AFLIBERCEPT": 72.65942524143358, "AVASTIN": 4.7452756653108565, "BEOVU": 64.95328821927362, "BROLUCIZUMAB": 48.52307633803014, "CELLCEPT": 0.8851422337802646, "CICLOSPORIN": 0.5769085508752108, "DEXAMETHASONE": 6.634141003208802, "EYLEA": 1942.594553388283, "LEVOFLOXACIN": 3.498544422772712, "MVASI": 48.67939417933724, "MYCOPHENOLATE": 8.316813263237535, "NEVANAC": 66.42183283252882, "VORICONAZOLE": 3.649767260934433, "null": 0.4779747472047342}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4163.json
index 36d359c3245..ad8fa14463a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4163.json
@@ -1 +1 @@
-{"null": 1.2750659248573155}
\ No newline at end of file
+{"ESMYA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4164.json
index 2eaa598f27b..a4c93c1125d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4164.json
@@ -1 +1 @@
-{"null": 1.53567740245871}
\ No newline at end of file
+{"null": 0.8456827935637452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4165.json
index 564dc1f770f..e7b14c25d22 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4165.json
@@ -1 +1 @@
-{"ABATACEPT": 11.724179488087708, "ACETAMINOPHEN": 32.997923253061934, "ACLIDINIUM": 3.8833784063394505, "ADALIMUMAB": 9.970955755179384, "AMBRISENTAN": 3.788780259867505, "ANAKINRA": 20.73302986042013, "ANORO": 3.0078279284266363, "APREPITANT": 36.56523764826924, "ARAVA": 5.669340981066956, "AVANDIA": 1.3907103078374663, "BENLYSTA": 5.910832044256317, "BENRALIZUMAB": 16.699276260770333, "BIKTARVY": 1.8583172510224728, "BUDESONIDE": 4.195023227944715, "CARMUSTINE": 4.719764665112564, "CELLCEPT": 1.0885352305976, "CHLORHEXIDINE": 47.555122045737264, "CIMZIA": 15.222508493103383, "COMBIVIR": 1.2286709488347836, "COTELLIC": 1.6732273065275078, "CYTARABINE": 1.7713931593990209, "DOXORUBICIN": 1.114112952625498, "ENBREL": 1.2419876758134398, "ESBRIET": 2.504100589141831, "ETANERCEPT": 4.136068713236246, "EVENITY": 6.089371274751175, "FASENRA": 1.311463344489065, "FILGRASTIM": 4.718735223307243, "GARDASIL": 1.1458469352461722, "GAZYVARO": 2.460101203810525, "HERCEPTIN": 2.488874156373861, "HIZENTRA": 3.579308857100964, "ICLUSIG": 1.3643277081921985, "INCRUSE": 5.66829416162152, "INFLIXIMAB": 1.28401202541026, "INTRONA": 1.887244360803762, "ISENTRESS": 1.7572538677415348, "JANUMET": 1.2626786541908288, "JANUVIA": 1.007583645891478, "KEYTRUDA": 1.950478389140644, "LEFLUNOMIDE": 2.501292671760513, "LUTATHERA": 70.3279944907816, "MEPOLIZUMAB": 2.541509423199464, "METHOTREXATE": 1.2991154034160486, "NUCALA": 2.1149261151146166, "ORKAMBI": 1.3265083292261393, "PEGASYS": 1.0779076413394844, "PEMBROLIZUMAB": 1.4811315650005332, "PLUVICTO": 167.9114742317682, "RELVAR": 2.139037416133213, "RITUXIMAB": 4.5627170500453085, "ROACTEMRA": 3.585409656612296, "SOLIRIS": 1.4280185638404082, "SYNAGIS": 3.151826655051102, "TAMIFLU": 1.00819652886819, "TRELEGY": 3.443456257020577, "TRIUMEQ": 2.4291469746753998, "VELTASSA": 2.848164425155161, "VOTRIENT": 2.2008259465544318, "ZIAGEN": 4.426544322570443, "ZOSTAVAX": 6.343437788983428}
\ No newline at end of file
+{"MAVENCLAD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4166.json
index 8bdb06f64e7..6f390cddce3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4166.json
@@ -1 +1 @@
-{"null": 2.140171203093644}
\ No newline at end of file
+{"ZOSTAVAX": 18.06408428868502, "null": 1.661381676766379}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4167.json
index 15b9d2e20e3..456d2f2b964 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4167.json
@@ -1 +1 @@
-{"ADCIRCA": 1.20130689687631, "ADEMPAS": 1.3360295664002242, "AMBRISENTAN": 2.336109502701676, "APIDRA": 1.2358136075599324, "AUBAGIO": 1.259776528964564, "AVONEX": 2.199414154102292, "AYESURBY": 63.51362596336912, "BENLYSTA": 4.429623282811039, "BOSULIF": 5.318224218804581, "BRAFTOVI": 2.985956947198102, "BYDUREON": 2.071372127864082, "CANNABIDIOL": 1.387906293695749, "CERTOLIZUMAB": 3.137524462066356, "CHAMPIX": 1.0350526221791123, "CIMZIA": 1.4371066218143596, "COSENTYX": 1.304654720398761, "COVID19": 2.2854850539468843, "DALIRESP": 7.168633491688431, "DULAGLUTIDE": 3.139698331516847, "DUPIXENT": 3.634660844363245, "ENTRESTO": 1.053155844042035, "ESBRIET": 1.338084284234375, "EXFORGE": 1.1995967540310035, "EXJADE": 1.5905680572654397, "FASENRA": 2.3052761084296542, "FENTANYL": 1.034594948428016, "FLUCELVAX": 1.3067922539321648, "FULVESTRANT": 1.058316151470068, "GLUCAGON": 1.5342296404328128, "HIZENTRA": 1.004190387153216, "HUMALOG": 2.417163991948005, "HUMIRA": 1.4221964393872015, "HYQVIA": 3.7442010750574433, "IBRANCE": 4.036742672154752, "IMBRUVICA": 1.246111302289995, "INCRUSE": 3.4209387777808127, "INLYTA": 1.8180129842729416, "INSULIN": 1.1902446968419431, "JARDIANCE": 1.1125333022305004, "KAFTRIO": 2.2729561959105795, "KALYDECO": 5.284251582870279, "KESIMPTA": 1.3687399679111578, "KISQALI": 1.171810856066485, "LANTUS": 1.7172825280714883, "LATUDA": 1.3381840154862752, "LONSURF": 1.6210443071161529, "LUTATHERA": 4.355454135335968, "LUTETIUM": 2.773754497421828, "LYRICA": 2.3341780381653754, "MEKINIST": 1.0008341562767888, "METHOTREXATE": 2.1048150467018893, "NEULASTA": 1.4087576731856808, "NINLARO": 3.304630295936773, "NUCALA": 2.0996141618069, "OCALIVA": 1.1623347956901398, "OCRELIZUMAB": 3.0043904013298826, "OCTREOTIDE": 4.5321324450549, "OMALIZUMAB": 3.2337496212121875, "OPSUMIT": 2.4235401947604167, "ORKAMBI": 3.112634432889556, "OXYBUTYNIN": 1.6605200043319364, "PEGINTRON": 1.0361757467387225, "PIRFENIDONE": 8.242357090670469, "PLEGRIDY": 1.349096737053305, "RAPAMUNE": 3.262851459588308, "REVATIO": 5.812672608819377, "RINVOQ": 1.09782913395036, "RUBRACA": 2.1399406483950565, "RUCONEST": 2.6508149923534488, "RYBELSUS": 1.0175003472966018, "SAXENDA": 2.102160483761197, "SHINGRIX": 1.7276072272120844, "SIMPONI": 2.1424557833085958, "SKYRIZI": 1.0641152643959058, "SOLIRIS": 1.0671451074615297, "SPINRAZA": 1.387477718336192, "SUBOXONE": 2.0168370197313, "SUTENT": 1.855162905356392, "SYNAGIS": 3.071927764491293, "TELMISARTAN": 2.153865259770189, "TIVICAY": 1.3094650784057258, "TOUJEO": 1.604594095417684, "TOVIAZ": 2.291088240965124, "TOZINAMERAN": 3.2213659858359653, "TRELEGY": 3.4542163024751527, "TRULICITY": 3.754518789071537, "VELTASSA": 2.835803713512031, "VFEND": 1.689245154999786, "VIAGRA": 1.5669242752072567, "VOTRIENT": 1.819542341782496, "XALKORI": 1.4392249975659044, "XELJANZ": 5.488495275281959, "XOFIGO": 1.278065012897718, "XOLAIR": 1.8342888384914824, "XTANDI": 2.0692474149456146, "XYREM": 1.0503216230340535, "ZEJULA": 3.566532500852188}
\ No newline at end of file
+{"null": 1.1321470499715232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4168.json
index 3e83097f5cf..0fefb6dedf9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4168.json
@@ -1 +1 @@
-{"null": 1.87100637445853}
\ No newline at end of file
+{"PREVENAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4169.json
index 752e9059dad..739727cc95f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4169.json
@@ -1 +1 @@
-{"null": 1.1773695953319565}
\ No newline at end of file
+{"COMIRNATY": 2.4919339227839763, "SPIKEVAX": 0.6223095869488435, "null": 0.2024364314839636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/417.json
index e3bdabb6eb2..3d10e40cbce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/417.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/417.json
@@ -1 +1 @@
-{"ASPARAGINASE": 319.67728143141954}
\ No newline at end of file
+{"null": 1.006633644640497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4170.json
index 20d1fa5c97d..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4170.json
@@ -1 +1 @@
-{"CHAMPIX": 3.2991472309901693, "CYMBALTA": 1.226156603493961, "GARDASIL": 4.387385125561347, "KEPPRA": 1.6869131443219638, "OLANZAPINE": 2.8556700212093324, "TAMIFLU": 4.0243510242320815, "VFEND": 9.487251932704591, "ZYPREXA": 2.438440532483894, "null": 1.9079218677598628}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4171.json
index 752e9059dad..5c9df36d017 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4171.json
@@ -1 +1 @@
-{"null": 1.1773695953319565}
\ No newline at end of file
+{"AZATHIOPRINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4172.json
index 7e978287612..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4172.json
@@ -1 +1 @@
-{"GARDASIL": 62.68624457740534, "SPIKEVAX": 10.158963537880574, "ZYPADHERA": 113.16399785885174}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4173.json
index 59f5980e91b..36ce4e47aab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4173.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 4.614953050810559, "ARAVA": 4.2106916915654615, "COMTAN": 14.23706885878834, "ELIQUIS": 1.6816279021240612, "ENBREL": 4.829618637233338, "OLANZAPINE": 2.45125955451049, "OPTIMARK": 3.136138345715496, "SHINGRIX": 4.709129800598367, "SIMPONI": 1.5796373933763124, "STELARA": 1.5393405555054032, "TOZINAMERAN": 1.2021604358530185, "XELJANZ": 1.0001606058513417, "null": 1.0884268330775737}
\ No newline at end of file
+{"null": 4.1447512675523255}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4174.json
index a3b13aee44e..ff36692769e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4174.json
@@ -1 +1 @@
-{"null": 1.024567463334371}
\ No newline at end of file
+{"ABILIFY": 1.8740229892929925, "BIKTARVY": 16.436345289081938, "BRIDION": 45.7840241160085, "CELLCEPT": 2.0515938683856443, "CICLOSPORIN": 2.6056459670249867, "COMIRNATY": 0.0404384571117655, "CYMBALTA": 0.9441868768470896, "ELIQUIS": 0.6691348744336513, "EXJADE": 2.641980853039686, "FENTANYL": 1.6012894580337165, "GARDASIL": 1.4323129266231265, "HARVONI": 3.7339567196810086, "ISENTRESS": 10.425361401651664, "JARDIANCE": 2.088146669052517, "KALETRA": 15.179993097778643, "KEPPRA": 1.2309416952272978, "KEYTRUDA": 1.1855378204228808, "MIDAZOLAM": 5.454695916300365, "NUCALA": 2.1449736692008634, "OLANZAPINE": 3.3650260536755736, "OPSUMIT": 4.85886330971155, "REMDESIVIR": 20.598655543198035, "SIMPONI": 1.151319609965713, "SPIKEVAX": 0.6681172369279508, "TRACLEER": 10.505880620412116, "TRELEGY": 3.0452775394850256, "TRUVADA": 0.5963303968562161, "VAXZEVRIA": 0.0516461511608925, "XOLAIR": 1.3169948903704374, "ZYPREXA": 3.821457620439124, "null": 1.6815865829468388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4175.json
index 4e7c32a5bd3..39e9e7da6ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4175.json
@@ -1 +1 @@
-{"AXICABTAGENE": 701.3511367824474, "BREYANZI": 497.375138176136, "CYTARABINE": 5.067830109690039, "DOXORUBICIN": 11.979266060860573, "EPCORITAMAB": 150.5355155179341, "KYMRIAH": 442.8114166519695, "NIVOLUMAB": 29.267269951826894, "TISAGENLECLEUCEL": 378.3965970313274, "YESCARTA": 2252.4733315214685}
\ No newline at end of file
+{"BRIDION": 122.413417303142, "NAGLAZYME": 85.13119231268217, "null": 2.9387349126229303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4176.json
index 5135e83b92a..f876e4fce45 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4176.json
@@ -1 +1 @@
-{"ABACAVIR": 17.352714529019355, "ALEMTUZUMAB": 4.207156710514938, "AMIKACIN": 6.272124571394586, "AMINOSALICYLIC": 1.339829089232953, "ASPARAGINASE": 2.080511778153732, "ATAZANAVIR": 51.91010536837692, "ATRIPLA": 2.085008705322505, "BIKTARVY": 62.17207505972675, "BUSULFAN": 1.6231639566736598, "CELSENTRI": 39.17421059660683, "COBICISTAT": 188.4828077047642, "COMBIVIR": 12.806362652213348, "CRIXIVAN": 9.493684024709797, "DARUNAVIR": 153.63691266766077, "DESCOVY": 67.9189795859046, "DEXAMETHASONE": 1.620637798813222, "DOLUTEGRAVIR": 203.1557820626649, "EFAVIRENZ": 236.99657015575752, "EMTRICITABINE": 156.74902480651065, "EMTRIVA": 297.824846055731, "EPIVIR": 60.00885722172054, "FILGRASTIM": 17.22886813102781, "FUZEON": 122.55659360463837, "GANCICLOVIR": 9.737013362436642, "GENVOYA": 25.972807278919174, "INDINAVIR": 37.928620840209845, "INFLIXIMAB": 8.846545418432335, "ISENTRESS": 55.17842015193536, "KALETRA": 24.574738601049937, "LAMIVUDINE": 240.4610028291607, "LEVOFLOXACIN": 1.081977866220028, "LOPINAVIR": 26.73939425175821, "MYCOPHENOLATE": 2.537333217450452, "NORVIR": 36.19482630371997, "PREZISTA": 115.58123582248996, "RALTEGRAVIR": 165.08883489826445, "RITUXIMAB": 3.4521560984508524, "STOCRIN": 50.74421148408263, "STRIBILD": 3.661143387132785, "TENOFOVIR": 12.867663194107063, "TIVICAY": 117.08157361621396, "TRIUMEQ": 21.4799484891294, "TRUVADA": 6.012529462054437, "VIREAD": 10.533889057586588}
\ No newline at end of file
+{"ROTATEQ": 3157.629152286781, "null": 0.1331088131712348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4177.json
index cdb8c6fd216..d00c8798370 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4177.json
@@ -1 +1 @@
-{"EMTRICITABINE": 274.1748553756677, "TRUVADA": 10.352984520321906}
\ No newline at end of file
+{"BRINTELLIX": 4.006684959264616, "BUPRENORPHINE": 6.49203759473958, "COMIRNATY": 0.2863200394379761, "LATUDA": 13.99529255170698, "PEGASYS": 1.7772556098638763, "SPIKEVAX": 0.2651103545418576, "SUBOXONE": 8.182732758732588, "SUTENT": 1.2099886538406692, "TOZINAMERAN": 1.033456253805269, "VAXZEVRIA": 0.2719696896016886, "XELJANZ": 3.321212271238428, "null": 1.6349893498951775}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4178.json
index 1751640dc13..e63d746518a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4178.json
@@ -1 +1 @@
-{"DARUNAVIR": 177.95585838105103, "DOLUTEGRAVIR": 372.8722313325229, "EFAVIRENZ": 281.9161054116521, "EMTRICITABINE": 200.26380668698064, "TRUVADA": 6.891947290869579}
\ No newline at end of file
+{"BUSULFAN": 108.63654156031234, "CICLOSPORIN": 46.096587715239096, "null": 0.4321563636734544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4179.json
index b32b5558c0c..c6f1ff7626a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4179.json
@@ -1 +1 @@
-{"ABACAVIR": 1.4548955681026097, "AIMOVIG": 1.3222754816100757, "ALEMTUZUMAB": 3.223893880663861, "AVAMYS": 3.0909841125903803, "BELIMUMAB": 8.776419611016381, "BENLYSTA": 4.0110913209192605, "BOSULIF": 2.4220157521519208, "COMIRNATY": 1.0806908167501974, "COSENTYX": 2.097659493482929, "ENBREL": 3.026578798794174, "FASENRA": 2.3549444258227687, "GARDASIL": 4.16992911048345, "HARVONI": 2.7879453791831583, "HUMIRA": 1.1833584509046502, "IBRANCE": 5.517148268561308, "KEYTRUDA": 1.0787579770933522, "NUCALA": 4.320347479083358, "OMALIZUMAB": 2.5672974508663997, "OZEMPIC": 22.509212023135564, "PEGASYS": 1.254955967049849, "PEGINTRON": 1.8357776095951424, "RAPAMUNE": 4.540348188406744, "REVLIMID": 4.050934355889792, "RIBAVIRIN": 2.439683977107897, "SHINGRIX": 1.421106110745348, "SIMPONI": 2.821191192428743, "SUTENT": 1.9247992574432, "TOZINAMERAN": 1.9873604812066716, "VFEND": 2.1204680461567063, "XELJANZ": 6.306799815583306, "ZOSTAVAX": 29.045554190561877}
\ No newline at end of file
+{"BUSILVEX": 413.5642157944732, "BUSULFAN": 186.73237052182745, "CICLOSPORIN": 22.73935778598899, "CYTARABINE": 16.921972193368926, "DEXAMETHASONE": 54.041685561337545, "null": 0.2953221114255725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/418.json
index 561f9897db1..cbf7994c7a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/418.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/418.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 12.688749454675072, "ELIQUIS": 7.797573004131726, "METHOTREXATE": 18.634936975850778}
\ No newline at end of file
+{"ABILIFY": 7.524988673457317, "BUDESONIDE": 4.009889248131433, "CHAMPIX": 6.64324411259996, "CYMBALTA": 2.8586354447976894, "MELATONIN": 33.59825451496787, "PEGASYS": 2.148644745952752, "PEGINTRON": 10.367670195178016, "SUBOXONE": 13.524105551343228, "ZYPREXA": 6.73902509706444, "null": 1.649551359175386}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4180.json
index 794acee4fec..e51923f9fdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4180.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 11.617157084676991, "ALISKIREN": 4.961768311648302, "ASPARAGINASE": 1.0329216079661294, "AVASTIN": 1.7841190277867844, "BEVACIZUMAB": 1.22875572370288, "BRILIQUE": 1.6671676301060092, "BUSULFAN": 1.1176605066208996, "CAPSAICIN": 220.03782577967883, "COVID19": 1.1483456441702715, "DEXAMETHASONE": 1.0042279382219774, "ENTYVIO": 2.5218566273135266, "FASENRA": 1.2287679144432528, "GANCICLOVIR": 2.686042786103918, "GARDASIL": 2.810102750169865, "HARVONI": 1.036477618904669, "INTRONA": 3.9606177576914714, "IPILIMUMAB": 6.658732495992841, "KEYTRUDA": 5.553047716682348, "LEMTRADA": 44.39309954496417, "MMRVAXPRO": 6.732366864583718, "NIMENRIX": 1.7175415642364649, "NPLATE": 19.30216738565376, "OPDIVO": 3.2852145534871084, "PANTOPRAZOLE": 2.2253361484162384, "PEGASYS": 3.4697071477254227, "PEGINTERFERON": 4.159875894222123, "PEGINTRON": 2.62063852971095, "PEMBROLIZUMAB": 3.804977470381414, "PLAVIX": 1.2292741347539888, "PREVENAR": 25.78481329817391, "RIBAVIRIN": 2.3115701136270284, "ROTATEQ": 8.410311648318114, "SYNAGIS": 1.3702512258195343, "TAMIFLU": 1.2954769531241077, "TOZINAMERAN": 1.5198814259665387, "VAXZEVRIA": 1.7196245312456184, "VENETOCLAX": 2.607625791171775}
\ No newline at end of file
+{"COMIRNATY": 5.683291503425447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4181.json
index eef37983f10..c61208d43e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4181.json
@@ -1 +1 @@
-{"AXITINIB": 31.67364996594425, "DOXORUBICIN": 10.378304862037805, "IPILIMUMAB": 39.4604514723791, "KEYTRUDA": 259.568585301724, "OPDIVO": 233.0824053732555, "PEMBROLIZUMAB": 12.18187611565332}
\ No newline at end of file
+{"EMTRICITABINE": 294.15624518269175, "null": 1.9907054157872064}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4182.json
index 7a0fa37a2e1..f61890b3374 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4182.json
@@ -1 +1 @@
-{"IPILIMUMAB": 66.64906496063064, "KEYTRUDA": 106.5273546054814, "OPDIVO": 111.99013875702488, "PEMBROLIZUMAB": 218.3804629883757}
\ No newline at end of file
+{"COMIRNATY": 0.7783286922797332, "SPIKEVAX": 0.6993792289607058, "TOZINAMERAN": 3.5281038802941698, "VAXZEVRIA": 0.184542746813636, "XOLAIR": 6.504797389452493, "null": 1.7970024925858448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4183.json
index 49e8126b344..cdd48645cf8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4183.json
@@ -1 +1 @@
-{"IPILIMUMAB": 78.92881584574202, "KEYTRUDA": 134.24104214351402, "OPDIVO": 91.7969739074402, "PEMBROLIZUMAB": 225.4212119315721}
\ No newline at end of file
+{"null": 0.3992861189850491}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4184.json
index 8c54adabb0c..38cea844a9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4184.json
@@ -1 +1 @@
-{"KEYTRUDA": 360.8979806337396, "OPDIVO": 70.12170709435715}
\ No newline at end of file
+{"null": 1.9731583774522563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4185.json
index 10cebd224f0..f918d02530e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4185.json
@@ -1 +1 @@
-{"KEYTRUDA": 82.35272280888942}
\ No newline at end of file
+{"ADALIMUMAB": 0.4689134727666647, "ALEMTUZUMAB": 9.734246503408553, "ALIMTA": 6.178735748091023, "ASPARAGINASE": 37.05199396358634, "AVASTIN": 4.325311608423399, "BENLYSTA": 2.0019553084667354, "BEVACIZUMAB": 4.476629499169423, "CAPECITABINE": 11.7759730299285, "CARMUSTINE": 33.228963411339805, "CELLCEPT": 2.6668628730460027, "CICLOSPORIN": 1.4724692760063622, "CIMZIA": 0.5545072314484875, "COMIRNATY": 0.231070880858644, "COSENTYX": 3.3080518573333944, "CYTARABINE": 4.548323001829614, "DOCETAXEL": 8.504612285310422, "ENTYVIO": 6.376681579869368, "FASLODEX": 1.835591772020241, "FILGRASTIM": 11.024011570548574, "GARDASIL": 0.7440683159246301, "HUMIRA": 1.5699932377046883, "IPILIMUMAB": 12.609878247950771, "IRINOTECAN": 9.121932925422524, "JEVTANA": 6.867742130091692, "KEYTRUDA": 4.84549699662537, "LANTUS": 0.5182891524119151, "OPDIVO": 6.857863249905643, "ROTATEQ": 17.220739490262165, "SIMPONI": 0.9421719386966168, "SOMATROPIN": 18.699391002719537, "SPIKEVAX": 0.1694513484183232, "STELARA": 1.15774939789705, "SUTENT": 0.4316882132115088, "TOZINAMERAN": 0.2245760472939367, "TRODELVY": 8.783494134932793, "VAXZEVRIA": 0.0610897351123317, "XELJANZ": 1.0055307568869964, "XELODA": 13.7171912538231, "YERVOY": 6.830994180042691, "null": 1.0202324638390443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4186.json
index 0a20dd9fc26..2e311a37516 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4186.json
@@ -1 +1 @@
-{"IPILIMUMAB": 98.94122353716833, "KEYTRUDA": 93.16676723494518, "OPDIVO": 385.580392753696, "PEMBROLIZUMAB": 110.2914143779514}
\ No newline at end of file
+{"BRAFTOVI": 20.562960322257915, "CELLCEPT": 6.9104187842182805, "CIMZIA": 3.172898137501744, "COMIRNATY": 0.115820278863689, "ENTYVIO": 9.82426809384146, "IBRANCE": 4.492083945773895, "KEYTRUDA": 3.897537586337428, "PEGINTRON": 8.562411264644265, "XELJANZ": 7.408052506820002, "null": 1.042107323691819}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4187.json
index fa35429e05b..61219823aa0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4187.json
@@ -1 +1 @@
-{"IPILIMUMAB": 284.9756724361475, "KEYTRUDA": 105.58729924737008, "OPDIVO": 68.50200807486466, "PEMBROLIZUMAB": 88.13259325476984}
\ No newline at end of file
+{"ASPARAGINASE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4188.json
index d57d23da329..9fea099a841 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4188.json
@@ -1 +1 @@
-{"KEYTRUDA": 88.82862638785676, "OPDIVO": 135.6052457121074}
\ No newline at end of file
+{"ALEMTUZUMAB": 129.15432764238912, "null": 0.4205167284081899}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4189.json
index 64a86f79c28..3f53234f113 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4189.json
@@ -1 +1 @@
-{"ABRAXANE": 17.59032851999298, "ALIMTA": 3.896940114643466, "AXITINIB": 13.01830059839609, "BRAFTOVI": 15.094653764235456, "CABOMETYX": 4.612208180959077, "INFLIXIMAB": 15.64998902019602, "INLYTA": 2.363354522636749, "IPILIMUMAB": 296.79190779537004, "KEYTRUDA": 138.07732784991654, "NIVOLUMAB": 19.27855314949008, "OPDIVO": 153.57751843105626, "PEMBROLIZUMAB": 87.02014699375799, "YERVOY": 9.312142354077356}
\ No newline at end of file
+{"ALEMTUZUMAB": 17.04930928386789, "ASPARAGINASE": 278.03534902497915, "CICLOSPORIN": 5.414890676256654, "CYTARABINE": 61.83884298708227, "OCEAN": 1176.461061785761, "REMICADE": 36.44380738892816, "null": 0.4846443952708406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/419.json
index 10d7a431a41..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/419.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/419.json
@@ -1 +1 @@
-{"ACE": 9.675285477397145, "AERIUS": 3.1305181833441957, "AFINITOR": 1.3395533759566085, "APIXABAN": 3.885427177458935, "APROVEL": 6.319003364052135, "BEXSERO": 2.6539705283655963, "BONVIVA": 1.103493064862073, "BOTULINUM": 16.02034635742221, "BRIDION": 2.566544524063437, "BRILIQUE": 1.1486844349851, "BYDUREON": 1.4458700868346666, "C1": 17.53470246021304, "CINRYZE": 7.445373446651264, "COAPROVEL": 5.2400299785809406, "DESLORATADINE": 1.8006282494751724, "DUPIXENT": 1.0601413999698657, "EFIENT": 1.278293027649116, "ENALAPRIL": 7.385229777316709, "ENTRESTO": 8.961703665004547, "EUCREAS": 4.353967507455475, "EVEROLIMUS": 1.1156650599049005, "EXFORGE": 2.980556821838915, "FASENRA": 1.767131966924895, "FENTANYL": 1.09886412603075, "GALVUS": 3.2202998347327254, "HUMAN": 1.056668039159451, "HYDROCHLOROTHIAZIDE": 4.821075652509352, "HYDROCORTISONE": 1.1003753364446571, "IBUPROFEN": 3.508300677439365, "ICATIBANT": 98.69102282093216, "IRBESARTAN": 5.969298027062175, "JANUMET": 1.2002395490371591, "JANUVIA": 1.3434580932061655, "JINARC": 79.35818143004069, "KARVEA": 8.718896859635164, "KARVEZIDE": 6.88749549810547, "KIVEXA": 1.3523581072845603, "LEVOFLOXACIN": 1.5932715328240372, "MICARDIS": 5.930562057395212, "MICARDISPLUS": 2.5709492481470337, "MIDAZOLAM": 1.0954421598465995, "MIXTARD": 1.4495969976194043, "NIMENRIX": 2.0193988998842736, "OLAPARIB": 1.4304657989690346, "OMALIZUMAB": 2.38977781356213, "ONCASPAR": 7.957896384667647, "ONGLYZA": 1.1935908191883955, "PLAVIX": 1.5927206658323398, "PRITOR": 6.576439548123348, "PRIVIGEN": 1.2951217743222108, "PROTELOS": 2.879188159190186, "RANOLAZINE": 1.9761783707293543, "RAPAMUNE": 1.2098579019441558, "RASILEZ": 7.8232050529932655, "RELVAR": 1.183382443553747, "RILUTEK": 2.397005643615922, "RIVAROXABAN": 1.255733065240272, "RIXATHON": 1.7808660098713978, "SIROLIMUS": 7.539282653142957, "SITAGLIPTIN": 3.835539714065976, "SUFENTANIL": 1.725103095597671, "TAMIFLU": 1.0252693875092922, "TEKTURNA": 4.852526923056708, "TELMISARTAN": 7.017530788545577, "TORISEL": 2.593441455580831, "VALSARTAN": 3.918305752864459, "VELMETIA": 5.602820157227052, "VICTOZA": 1.2402768806075164, "XOLAIR": 4.969808796998703, "ZEPATIER": 1.5802572731207027, "ZYLLT": 4.551821124708186, "null": 3.72060064163402}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4190.json
index 90b2eebff76..ae336bffda7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4190.json
@@ -1 +1 @@
-{"IPILIMUMAB": 154.62525109794524, "KEYTRUDA": 108.8962407920274, "OPDIVO": 80.50611893721674, "PEMBROLIZUMAB": 138.76480206238105}
\ No newline at end of file
+{"BUSULFAN": 92.02161585888209, "null": 0.6673674910171996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4191.json
index 8379ca2d636..f67bb4fccae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4191.json
@@ -1 +1 @@
-{"ALIMTA": 11.472469817689513, "AXITINIB": 87.1198856764298, "BRAFTOVI": 15.801275667181104, "CABOMETYX": 10.445681181034123, "INLYTA": 23.705167993430408, "IPILIMUMAB": 32.07000010915875, "KEYTRUDA": 191.11539641465163, "OPDIVO": 206.16830038711043, "PEMBROLIZUMAB": 17.702906219432123}
\ No newline at end of file
+{"null": 1.1042497054935116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4192.json
index c1df990abd9..58ae12b51e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4192.json
@@ -1 +1 @@
-{"ALIMTA": 5.003016610445751, "AVELUMAB": 55.05827703969306, "AXITINIB": 26.97754940870548, "BEVACIZUMAB": 4.86306683018024, "IPILIMUMAB": 388.0625496062652, "KEYTRUDA": 87.41113155200065, "OPDIVO": 99.53363435730144, "PACLITAXEL": 18.712096058685947, "PEMBROLIZUMAB": 159.59737572674177}
\ No newline at end of file
+{"EMPAGLIFLOZIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4193.json
index 5c3cbd2395f..d5f22158be1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4193.json
@@ -1 +1 @@
-{"AXITINIB": 56.16742196589801, "IPILIMUMAB": 56.0123608654396, "KEYTRUDA": 323.0698645750154, "OPDIVO": 59.723152833924566, "PEMBROLIZUMAB": 79.05340558283008}
\ No newline at end of file
+{"null": 1.686675360772094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4194.json
index af3660a37b4..c142b5287b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4194.json
@@ -1 +1 @@
-{"IPILIMUMAB": 856.2227396132345, "KEYTRUDA": 42.81127338715039, "OPDIVO": 136.43005773823856, "PEMBROLIZUMAB": 68.77815117475505}
\ No newline at end of file
+{"null": 1.395000896118496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4195.json
index 9e222c3a0e1..e9f602ab598 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4195.json
@@ -1 +1 @@
-{"AXITINIB": 75.94154727669668, "INLYTA": 6.001825255850177, "IPILIMUMAB": 44.30409769261316, "KEYTRUDA": 420.7737835460768, "OPDIVO": 55.93186619878118, "PACLITAXEL": 11.46201496584662, "PEMBROLIZUMAB": 108.51083532945196}
\ No newline at end of file
+{"ALEMTUZUMAB": 45.034012622649534, "BUSULFAN": 60.467703221925255, "CICLOSPORIN": 5.212880200659079, "CUBICIN": 195.76423322614875, "null": 0.5184625492082828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4196.json
index 04cabc29ac5..354bad607d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4196.json
@@ -1 +1 @@
-{"ALIMTA": 5.836701153509392, "CABOMETYX": 5.670059651046584, "IPILIMUMAB": 130.25320983857247, "KEYTRUDA": 117.05357930986636, "NIVOLUMAB": 43.27989002890576, "OPDIVO": 152.35088760516322, "PEMBROLIZUMAB": 252.31174980586215}
\ No newline at end of file
+{"ALEMTUZUMAB": 13.305630869153516, "AMIKACIN": 79.11836155207891, "ASPARAGINASE": 19.15116955114026, "BASILIXIMAB": 56.48677532816336, "BORTEZOMIB": 34.52327111328297, "BUSULFAN": 23.370574175765253, "CASPOFUNGIN": 41.98246259459722, "CELLCEPT": 3.39414802308786, "CICLOSPORIN": 11.250502220049237, "CLADRIBINE": 53.361230371685146, "CUBICIN": 45.219181603164905, "CYTARABINE": 8.532661766741862, "DEXAMETHASONE": 5.625619747362891, "GANCICLOVIR": 15.854964432961388, "KYMRIAH": 13.595702756095022, "MYCOPHENOLATE": 18.384731467801107, "RITUXIMAB": 3.6603812409776806, "SOLIRIS": 6.98605824612428, "null": 0.6524367021154589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4197.json
index c26950a3882..2646f7fc35a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4197.json
@@ -1 +1 @@
-{"IPILIMUMAB": 105.08007748062978, "KEYTRUDA": 160.6908292634454, "OPDIVO": 37.014866421035, "PEMBROLIZUMAB": 142.78294347950708}
\ No newline at end of file
+{"AZATHIOPRINE": 28.7023875449823, "CICLOSPORIN": 11.17034438914093, "SOLIRIS": 20.68554313048513, "null": 0.5172514752746683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4198.json
index 6b37c393dca..4a2881c13dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4198.json
@@ -1 +1 @@
-{"AXITINIB": 46.68329156981822, "IPILIMUMAB": 229.4228018276204, "KEYTRUDA": 126.54803606564856, "OPDIVO": 71.98375210372812, "PEMBROLIZUMAB": 222.96752296417367}
\ No newline at end of file
+{"CYTARABINE": 50.97053886214012, "null": 0.3994154939092192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4199.json
index da44607a449..c0b14432b8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4199.json
@@ -1 +1 @@
-{"IPILIMUMAB": 106.29353756716668, "KEYTRUDA": 84.43892864911557, "OPDIVO": 53.16995419712262, "PEMBROLIZUMAB": 163.0249869285506}
\ No newline at end of file
+{"ABRAXANE": 11.859604200114305, "ADCETRIS": 23.40533475392848, "ALIMTA": 6.342254726887617, "AMINOSALICYLIC": 3.209273320618893, "AVASTIN": 5.7624495807111416, "BEVACIZUMAB": 2.4429046799593, "BRAFTOVI": 9.463731640467063, "BUSULFAN": 2.44232834920476, "CABOMETYX": 2.9768280263463978, "CANCIDAS": 7.639021283501832, "CAPECITABINE": 5.457023765817839, "CASPOFUNGIN": 11.729271279627609, "CELLCEPT": 4.89026487135756, "CICLOSPORIN": 0.6398919651325442, "COMIRNATY": 0.1424729111961695, "COSENTYX": 0.773050684995478, "CYTARABINE": 1.5446285096819488, "DEXAMETHASONE": 3.915015587441159, "DOCETAXEL": 5.289659659040225, "HALAVEN": 8.024529103344896, "INLYTA": 2.7525149917432192, "IPILIMUMAB": 14.18662319144116, "IRESSA": 5.2064274348912765, "JAKAVI": 1.8765783143378825, "JEVTANA": 8.001727037253637, "KEYTRUDA": 16.60791368311092, "LEVETIRACETAM": 1.785483827794487, "LEVOFLOXACIN": 1.7028950171863677, "NEXAVAR": 2.2230404333965, "OPDIVO": 30.508664701013632, "PEGASYS": 0.5051114186098001, "PEMBROLIZUMAB": 3.135333840619102, "ROTATEQ": 3.9780205953263583, "SPIKEVAX": 0.0522689027065473, "SPRYCEL": 4.006317435139912, "STELARA": 0.6893579142219485, "STIVARGA": 1.711226436978255, "SUTENT": 0.6618357087829456, "TRASTUZUMAB": 65.77153017306227, "XELODA": 15.604784290694685, "YERVOY": 80.62849752865445, "null": 1.1093436858310817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/42.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/42.json
index 63d32bbee05..551e16a413c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/42.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/42.json
@@ -1 +1 @@
-{"AUBAGIO": 1.5888119978274269, "CIMZIA": 2.410748623436002, "ENOXAPARIN": 7.401587797330903, "EPIVIR": 13.029016481270984, "GARDASIL": 1.9056172244196736, "GONALF": 146.17175789126907, "KEPPRA": 4.8980690023963165, "LANTUS": 1.160577976306277, "SAXENDA": 5.70146086621288, "SIMPONI": 1.280048769500289, "TAMIFLU": 3.115044874824876, "ZYPREXA": 1.897944676408417, "null": 2.3734057252690675}
\ No newline at end of file
+{"COMIRNATY": 1.108429304103997, "SPIKEVAX": 0.5496861758847508, "TWINRIX": 26.63895069127133, "VAXZEVRIA": 0.4622857716985647, "null": 0.8618599312637232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/420.json
index 9d3c3e0b06c..a923d1474db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/420.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/420.json
@@ -1 +1 @@
-{"SPIKEVAX": 2.000706393077717}
\ No newline at end of file
+{"EXFORGE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4200.json
index 39355b78623..dd4c2fa5f70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4200.json
@@ -1 +1 @@
-{"IPILIMUMAB": 268.11830719659974, "KEYTRUDA": 82.38576537543292, "OPDIVO": 108.7827885815122, "PEMBROLIZUMAB": 97.79539167654733}
\ No newline at end of file
+{"null": 1.0744112584206518}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4201.json
index 89451b63150..0242520bc5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4201.json
@@ -1 +1 @@
-{"KEYTRUDA": 71.57359804206126}
\ No newline at end of file
+{"COMIRNATY": 0.090214257774541, "KEYTRUDA": 2.117081288607134, "NEXAVAR": 2.0096649774626254, "OSELTAMIVIR": 68.26254035280253, "PEGINTRON": 2.1140361391768483, "PLAVIX": 2.53314230941957, "SPRYCEL": 17.93716725282123, "SUTENT": 0.7655020965932018, "TAMIFLU": 85.3151506856073, "YERVOY": 37.19148447662393, "null": 2.1866712051101738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4202.json
index 5092feebe49..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4202.json
@@ -1 +1 @@
-{"IPILIMUMAB": 162.24804260204309, "KEYTRUDA": 42.0542566595739, "OPDIVO": 37.32379813315822, "PEMBROLIZUMAB": 76.49009480494051}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4203.json
index 8a3fa999bf6..73aab45ada5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4203.json
@@ -1 +1 @@
-{"IPILIMUMAB": 89.0312362604972, "KEYTRUDA": 175.430043451578, "OPDIVO": 105.10613000328917, "PEMBROLIZUMAB": 106.91384188795674}
\ No newline at end of file
+{"CYTARABINE": 46.37593003976208, "null": 0.7781746656273398}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4204.json
index 9cd2cff11a7..b438c9e8bf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4204.json
@@ -1 +1 @@
-{"KEYTRUDA": 86.4566241693717}
\ No newline at end of file
+{"null": 0.4922549821089204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4205.json
index dcdad1c5d82..e544f8881a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4205.json
@@ -1 +1 @@
-{"KEYTRUDA": 128.7659776574867}
\ No newline at end of file
+{"AVASTIN": 67.42780119024435, "ENTYVIO": 26.68968019775779, "STELARA": 13.332223906513269, "null": 0.5095496317069903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4206.json
index c63bf77e031..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4206.json
@@ -1 +1 @@
-{"KEYTRUDA": 231.1922072947446, "OPDIVO": 98.88086835554972, "PEMBROLIZUMAB": 41.03041589550981}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4207.json
index 8178a7a6abd..afe0763efdf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4207.json
@@ -1 +1 @@
-{"IPILIMUMAB": 349.93941749374187, "KEYTRUDA": 61.85443684482134, "OPDIVO": 85.8837163156792, "PEMBROLIZUMAB": 272.9409870106071}
\ No newline at end of file
+{"STELARA": 25.995409808280503, "null": 0.7406820408322193}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4208.json
index 740975e9462..57e2efe82dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4208.json
@@ -1 +1 @@
-{"IPILIMUMAB": 237.77810539460356, "KEYTRUDA": 130.0459572587717, "OPDIVO": 54.84933703834195, "PEMBROLIZUMAB": 87.25310306014602}
\ No newline at end of file
+{"null": 1.432158219725615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4209.json
index eeaf352f339..00fa187415a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4209.json
@@ -1 +1 @@
-{"APIXABAN": 2.832845719534628, "COMIRNATY": 48.83361139688855, "TOZINAMERAN": 4.121053531969557}
\ No newline at end of file
+{"CYTARABINE": 116.68565047832332, "SPINRAZA": 171.5457392307427, "SYNAGIS": 64.6643884308422, "null": 0.3444868127370784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/421.json
index 04f83c0802b..c258d7524b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/421.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/421.json
@@ -1 +1 @@
-{"null": 2.119843710264686}
\ No newline at end of file
+{"null": 3.445822455191633}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4210.json
index 1f66629c2d0..c079965f928 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4210.json
@@ -1 +1 @@
-{"BEXSERO": 3.763094068200025, "COMIRNATY": 7.256999281558455, "COVID19": 1.7952798121205404, "ELASOMERAN": 36.530906969268365, "FAMPYRA": 1.473033935322017, "GARDASIL": 1.0007803847720529, "HUMIRA": 1.3553879587108892, "NIMENRIX": 2.48268413298265, "PLEGRIDY": 1.366726425524796, "PREVENAR": 2.1891079209458777, "SPIKEVAX": 4.877326270163718, "TWINRIX": 2.2139374654013158, "VAXZEVRIA": 1.9584456854247665}
\ No newline at end of file
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4211.json
index 64d8d830230..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4211.json
@@ -1 +1 @@
-{"COMIRNATY": 6.688910052273217}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4212.json
index 588ef6b40f2..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4212.json
@@ -1 +1 @@
-{"ABACAVIR": 161.58609277409082, "ABATACEPT": 1.055990024331274, "ADALIMUMAB": 4.972039269810835, "AIMOVIG": 1.7097996208401791, "ANAKINRA": 1.7473098548974968, "BENLYSTA": 6.030819616535878, "CELLCEPT": 2.478989542550925, "COSENTYX": 2.918430167373996, "CYTARABINE": 2.117381157705677, "ENBREL": 8.689095809016184, "FILGRASTIM": 4.148600935072378, "GARDASIL": 1.3729746250045218, "HUMIRA": 7.502544293224453, "IBRANCE": 2.2790204096182807, "IMBRUVICA": 11.252779624983162, "KISQALI": 2.7072478251412746, "LEFLUNOMIDE": 9.104319473849802, "NUCALA": 1.012174275553466, "OCRELIZUMAB": 11.728567939078518, "ORENCIA": 41.19538630829245, "RINVOQ": 4.524245392290687, "RITUXIMAB": 2.85650044819195, "ROACTEMRA": 1.7341899014584004, "SOLIRIS": 1.4312187221670774, "SUTENT": 1.577262720888406, "XELJANZ": 3.000297820661051, "XOLAIR": 1.0802463398507576, "ZOSTAVAX": 1.0055910734067606}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4213.json
index 306a93e8b66..d6f1532ed4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4213.json
@@ -1 +1 @@
-{"GARDASIL": 12.967196997188552}
\ No newline at end of file
+{"null": 0.3793055732831707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4214.json
index 0310b8f6cd1..9bf62ca7f5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4214.json
@@ -1 +1 @@
-{"GARDASIL": 44.90256802070202, "SPIKEVAX": 4.260687219835851}
\ No newline at end of file
+{"ABATACEPT": 18.749146120960493, "ADALIMUMAB": 24.62397824919833, "APREMILAST": 96.69622785994478, "AZATHIOPRINE": 14.579606273008505, "CELECOXIB": 19.02226525195053, "CICLOSPORIN": 3.76025292438594, "CIMZIA": 4.328441253509409, "COMIRNATY": 0.3505217313191098, "COSENTYX": 39.07571443489129, "ENBREL": 10.64618368202364, "HUMIRA": 3.5018220447462163, "METHOTREXATE": 3.113725772571467, "SIMPONI": 3.2508450508298554, "SPIKEVAX": 0.1689851460573669, "null": 0.1750991866190961}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4215.json
index 56971a173e7..2b96d5ac351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4215.json
@@ -1 +1 @@
-{"ARAVA": 1.331047910427223, "HIZENTRA": 33.738866848222536, "RITUXIMAB": 13.363436198413766}
\ No newline at end of file
+{"null": 1.4001987331027643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4216.json
index 44cb1dbe794..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4216.json
@@ -1 +1 @@
-{"MEPOLIZUMAB": 48.167893669448745, "null": 1.3035198506775605}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4217.json
index 6d7cd8b8372..fad366d73ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4217.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4217.json
@@ -1 +1 @@
-{"COVID19": 4.154594980138139}
\ No newline at end of file
+{"ABILIFY": 3.2170994231650707, "ARIPIPRAZOLE": 3.5324079986065757, "COMIRNATY": 0.1823525049612637, "CYMBALTA": 1.4300492379429306, "GARDASIL": 1.2537747152092782, "HUMALOG": 1.9771222151428127, "KEPPRA": 2.949215496011369, "OLANZAPINE": 2.614860116807801, "SPIKEVAX": 0.2693809251033763, "TOZINAMERAN": 0.3686794309834443, "VAXZEVRIA": 0.3734671094557495, "XYREM": 55.01823440148234, "ZYPREXA": 3.4983951516448752, "null": 3.5385167764537124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4218.json
index 835bffa737c..2e72b668a8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4218.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4218.json
@@ -1 +1 @@
-{"ADVAGRAF": 139.8358572904043, "AZATHIOPRINE": 11.780541869409744, "CELLCEPT": 44.13018579337084, "CICLOSPORIN": 28.634089784155982, "MYCOPHENOLATE": 26.11632803558124, "TACROLIMUS": 248.0418648889223, "null": 1.7861237527549647}
\ No newline at end of file
+{"IBUPROFEN": 30.26608135453977, "null": 2.712549408506145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4219.json
index aa285771e5e..cde548e651d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4219.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4219.json
@@ -1 +1 @@
-{"ADVAGRAF": 203.18370510793835, "BASILIXIMAB": 27.704005804894063, "CELLCEPT": 18.36048461702587, "CICLOSPORIN": 60.65172255742176, "ENVARSUS": 292.806821929976, "EVEROLIMUS": 27.509769063503462, "KALETRA": 13.96089286266653, "MYCOPHENOLATE": 43.54833528534023, "RAPAMUNE": 77.82861309558291, "TACROLIMUS": 264.6432124536741, "VFEND": 17.888887628932846, "VORICONAZOLE": 24.32719721298393, "null": 1.0301754806828465}
\ No newline at end of file
+{"null": 1.7380871034356369}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/422.json
index ea4ceec65cc..0f20649561a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/422.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/422.json
@@ -1 +1 @@
-{"SPIKEVAX": 30.57591402254277}
\ No newline at end of file
+{"PACLITAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4220.json
index 27f1e27b1e4..3d34d774a97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4220.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4220.json
@@ -1 +1 @@
-{"AFINITOR": 1.248541298793126, "AIMOVIG": 1.9775558286156127, "ALEMTUZUMAB": 8.447408302109308, "AUBAGIO": 2.57865466571082, "AZATHIOPRINE": 5.250550230153238, "BENLYSTA": 10.19676707680172, "CAPECITABINE": 6.894928108034862, "CELLCEPT": 4.006832116069288, "CICLOSPORIN": 7.295618862887299, "CIMZIA": 3.0287213766976744, "COSENTYX": 4.439740198690783, "CYTARABINE": 3.823556269592133, "DEXAMETHASONE": 2.878827955960284, "ENBREL": 2.3579055559047446, "ENTYVIO": 2.517512360658384, "ERIBULIN": 103.42939245317604, "HUMIRA": 4.704860484842739, "IBRANCE": 5.212985762838488, "JAKAVI": 7.457681043790479, "LEMTRADA": 4.519662278784796, "METHOTREXATE": 7.1884626568275305, "MYCOPHENOLATE": 6.88959264136623, "NPLATE": 5.897940324943267, "NUCALA": 1.4876290663517622, "PEGASYS": 1.0218604700133078, "PEGINTRON": 1.0850744777348669, "RINVOQ": 8.604682647038587, "RITUXIMAB": 5.795676848269999, "ROACTEMRA": 3.630010803493457, "SOLIRIS": 6.524575619371689, "STELARA": 2.873254307844572, "SUTENT": 1.30396311528724, "XELJANZ": 11.315393917453394, "XOLAIR": 1.1115536688403131}
\ No newline at end of file
+{"ONCASPAR": 1281.4118526107254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4221.json
index a31695a4866..8309518f405 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4221.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4221.json
@@ -1 +1 @@
-{"AUBAGIO": 2.8176228730461337, "BRINTELLIX": 1.99253030657012, "BUDESONIDE": 1.542873484627403, "BUMETANIDE": 29.19821471069218, "BUPRENORPHINE": 8.362032667384627, "CHAMPIX": 9.715193054552389, "CYMBALTA": 1.222616326663515, "FENTANYL": 4.005052646931335, "KEPPRA": 1.693177971267491, "LYRICA": 9.84199815922839, "PREGABALIN": 3.151123067066041, "SHINGRIX": 1.6299545516842462, "SUBOXONE": 9.261469779098787, "null": 2.0811565734846176}
\ No newline at end of file
+{"null": 0.9603570280305574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4222.json
index 782e0e2ee2f..7b3aa3a9d26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4222.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4222.json
@@ -1 +1 @@
-{"ZOSTAVAX": 87.26031977037316, "ZYPREXA": 9.472145022956637}
\ No newline at end of file
+{"null": 1.4308638089904002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4223.json
index ec4da52987f..9977cee8e6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4223.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4223.json
@@ -1 +1 @@
-{"AIMOVIG": 6.574601778911032, "APIDRA": 1.7234319225187824, "ARAVA": 1.2288107028927542, "BENLYSTA": 2.748325754845046, "BYDUREON": 10.546640596722352, "BYETTA": 10.259747547109882, "CELLCEPT": 2.031749997539881, "CLOPIDOGREL": 1.1030958305728036, "FENTANYL": 1.451015775475109, "GARDASIL": 5.598179826764711, "HUMALOG": 6.906755723416346, "INSULIN": 3.4950962604679656, "JANUMET": 3.1634697441285624, "JANUVIA": 3.028640280251992, "JARDIANCE": 1.203451150599296, "LANTUS": 2.2463411472728363, "LYRICA": 1.8233883484748064, "METHOTREXATE": 1.539767464463488, "OPSUMIT": 1.0600416238696393, "OPTIMARK": 2.3389550206460554, "OZEMPIC": 24.96230459360585, "RYBELSUS": 31.856143089881357, "SAXENDA": 9.82577811679446, "TRESIBA": 13.91172119293204, "TRULICITY": 22.36237884837358, "VICTOZA": 20.08028268308285, "XELJANZ": 1.2785472297181513, "XOLAIR": 1.686897415393437, "ZYPREXA": 1.00375447472738, "null": 1.2216063840057974}
\ No newline at end of file
+{"null": 0.800415278061176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4224.json
index b5412ce9552..e4b7c027ac3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4224.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4224.json
@@ -1 +1 @@
-{"ABATACEPT": 26.35880766796328, "ACETAMINOPHEN": 43.76835572255833, "ADALIMUMAB": 12.113187967944675, "ANAKINRA": 2.705227249070439, "APREMILAST": 1.5184938890522863, "APREPITANT": 50.58495734397461, "ARAVA": 9.776260801158914, "AVASTIN": 3.2957296428401337, "BETAFERON": 1.3043235022031197, "BONVIVA": 3.9670913186831194, "CABOMETYX": 4.975864512822222, "CERTOLIZUMAB": 11.919250675325646, "CHLORHEXIDINE": 67.00948521742104, "CICLOSPORIN": 1.1914418094672083, "CIMZIA": 23.846800106694268, "COSENTYX": 1.3851470095237843, "CUBICIN": 1.3177226730418576, "ENBREL": 2.7830309969157194, "ENTYVIO": 1.1458870568402475, "EVISTA": 1.6463966643513186, "HUMALOG": 2.2494946416641057, "HUMIRA": 1.2240341812856164, "IBRANCE": 1.4623362766061236, "INLYTA": 2.0935331175948053, "JAKAVI": 1.0419295596764782, "JARDIANCE": 1.0260004974796284, "LEFLUNOMIDE": 2.775554771305538, "LENVIMA": 3.640410868017765, "LIRAGLUTIDE": 3.829771093948872, "LIXIANA": 1.4264292961155274, "METHOTREXATE": 1.165276692443871, "MYCOPHENOLATE": 2.2702477276897004, "NEXAVAR": 1.1416171238912525, "OFEV": 1.7764639624438587, "PROLIA": 7.726653681938115, "RAPAMUNE": 7.3023644694553855, "REMICADE": 1.4243508065904045, "RINVOQ": 1.056451782076167, "RITUXIMAB": 3.051832204922506, "ROACTEMRA": 2.662961609394065, "SIMPONI": 1.146800107639156, "SUTENT": 2.786844517765515, "VOTRIENT": 2.3266746471993858, "XELJANZ": 2.265580348416136, "ZOMETA": 5.11357132893882}
\ No newline at end of file
+{"ATRIPLA": 2.619649144025735, "null": 0.7120645845700431}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4225.json
index f223c11ccb6..95d54906558 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4225.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4225.json
@@ -1 +1 @@
-{"ABILIFY": 1.209517191688766, "ACLIDINIUM": 11.92162497011097, "ADALIMUMAB": 8.915119902712986, "AMINOSALICYLIC": 2.987953025820135, "ANAKINRA": 13.052524413582692, "AUBAGIO": 3.102638900809175, "BUDESONIDE": 3.329062205197135, "BUPRENORPHINE": 4.118207776924648, "CAPSAICIN": 236.64416130164483, "COMIRNATY": 1.2917215366760122, "DULOXETINE": 22.18324739720747, "ENTYVIO": 4.279331695949424, "FENTANYL": 1.0435016700844166, "HUMIRA": 7.238404263682648, "METHOTREXATE": 1.0873165824993398, "NUCALA": 2.7138071737065705, "OLANZAPINE": 1.2338900213918045, "XELJANZ": 3.168956449872104}
\ No newline at end of file
+{"null": 0.6110021031734242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4226.json
index 69d003b09b4..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4226.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4226.json
@@ -1 +1 @@
-{"null": 2.662923799026622}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4227.json
index 39da8778662..21f8e554eee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4227.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4227.json
@@ -1 +1 @@
-{"ABILIFY": 1.0915378694568842, "ADALIMUMAB": 2.08204229068418, "ALISKIREN": 9.11416505936791, "ANAKINRA": 4.63505431041742, "ARAVA": 1.7242064697118094, "ATRIPLA": 1.3770428297814, "AUBAGIO": 1.055594974483152, "BENLYSTA": 1.1449191882931826, "CAPSAICIN": 64.17147643935897, "CHAMPIX": 1.823866029686633, "CIMZIA": 1.1596583523398585, "COMIRNATY": 1.883249029552981, "ENBREL": 3.861505527848524, "FENTANYL": 1.5132722923602246, "GALAFOLD": 5.213511559014525, "GARDASIL": 3.219887370171268, "HUMIRA": 2.8296923124761046, "LYRICA": 1.9856831134808264, "SHINGRIX": 1.7581001384478845, "SPIKEVAX": 2.01232923308311, "STRIBILD": 2.0435730049528598, "TWINRIX": 2.9696472512372623, "VAXZEVRIA": 1.5216793080744986, "XELJANZ": 1.2905538074537402}
\ No newline at end of file
+{"null": 1.0377807121730769}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4228.json
index 8fc99f28665..403b30a658b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4228.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4228.json
@@ -1 +1 @@
-{"ABILIFY": 22.87384207231726, "CHAMPIX": 10.22638179235868, "CYMBALTA": 2.9326716628786214, "KEPPRA": 6.789559130478277, "PEGASYS": 3.646684457617973, "SUTENT": 1.5932224583878911, "null": 2.1065616452886915}
\ No newline at end of file
+{"AVAMYS": 53.65126727236075, "DEXAMETHASONE": 10.004408132091012, "FASENRA": 88.0875997363502, "MEPOLIZUMAB": 237.13138448907017, "NUCALA": 47.38852674578952, "TOBRAMYCIN": 74.65641238920456, "null": 0.4589742996946738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4229.json
index 792d2cdab5d..f0a841c0605 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4229.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4229.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4264243142985773}
\ No newline at end of file
+{"ARIPIPRAZOLE": 5.297627607709581, "BUDESONIDE": 17.980122558507603, "COMIRNATY": 0.1871730133335451, "DOCETAXEL": 10.160438199064352, "FASENRA": 14.49011516925103, "MEPOLIZUMAB": 21.9199178890184, "METHOTREXATE": 34.60868622018931, "NUCALA": 10.033321497836273, "OLANZAPINE": 5.100606400011758, "PEGASYS": 2.1210880057740438, "SPIKEVAX": 0.1437178268905436, "VARENICLINE": 178.9103912301595, "null": 0.5509016366335776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/423.json
index 5fd32a29ad6..cb0e9061823 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/423.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/423.json
@@ -1 +1 @@
-{"AVANDIA": 4.333558304004541, "BUDESONIDE": 4.842038965436102, "CELLCEPT": 2.288810818238165, "CLOPIDOGREL": 2.545312035007541, "ELIQUIS": 1.9368602448704677, "FORSTEO": 1.1934233664430507, "GARDASIL": 3.550093183006948, "HUMALOG": 2.959117705276686, "HYDROCORTISONE": 13.063279941254985, "ICLUSIG": 9.050060055837887, "LANTUS": 3.0127469238575046, "MIMPARA": 10.238481164956204, "PEGINTRON": 1.918830551663541, "PLAVIX": 3.764565025197937, "TASIGNA": 8.542773693010151, "VIAGRA": 5.424495460314242, "ZOSTAVAX": 1.0455107800168162, "null": 1.2102574478937702}
\ No newline at end of file
+{"null": 2.048058036459657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4230.json
index 8627aa04025..f34bb6ec19a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4230.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4230.json
@@ -1 +1 @@
-{"ABACAVIR": 8.16939694290088, "BUPRENORPHINE": 6.127622959244162, "COSENTYX": 4.772251005820685, "GARDASIL": 2.434518211837626, "RINVOQ": 19.33030849576726, "STELARA": 4.270597814197234, "ZOSTAVAX": 6.135473509847262}
\ No newline at end of file
+{"ACLIDINIUM": 11.046773925916243, "ADCIRCA": 4.262994294792495, "ALEMTUZUMAB": 5.0633914158842135, "ARANESP": 0.6540988427716351, "AUBAGIO": 0.91972518828984, "AVAMYS": 6.946869754819198, "AZATHIOPRINE": 6.862102527957227, "BENRALIZUMAB": 11.87626445710108, "BUDESONIDE": 13.465190152228306, "CLOPIDOGREL": 1.7646178937580304, "COMIRNATY": 0.1057897938324436, "COSENTYX": 1.5996486270925998, "CUBICIN": 23.656250907188188, "DUPILUMAB": 29.744665725515546, "DUPIXENT": 16.1346065222669, "ELIQUIS": 0.3557565975967058, "ENTRESTO": 1.5453925212584985, "ERLEADA": 9.165166724221438, "FASENRA": 46.55794372924296, "FLUTICASONE": 9.265379838599872, "GIOTRIF": 116.62312369149006, "IBUPROFEN": 1.682063562510123, "ISENTRESS": 3.570695739773754, "JANUVIA": 2.296252776057526, "KEPPRA": 0.9142524604936756, "KEYTRUDA": 2.956843160119042, "LEVETIRACETAM": 0.8742356372840528, "LEVOFLOXACIN": 2.4814225079434338, "LYRICA": 0.8244168096080273, "MEPOLIZUMAB": 15.137365945883689, "METHOTREXATE": 6.437408583660465, "MICAFUNGIN": 26.70384928505748, "NEXAVAR": 0.6771459050534334, "NOT": 2.407488415386257, "NUCALA": 15.994543648270492, "OLANZAPINE": 1.206369494950407, "OMALIZUMAB": 10.152072018524995, "OPDIVO": 4.270700288981342, "PEGASYS": 0.6082425635427658, "PEGINTRON": 1.4047162110856393, "PLAVIX": 1.3854691241037451, "ROACTEMRA": 2.2028935510378407, "SUTENT": 0.1942660211759772, "TAGRISSO": 1.6189663068143547, "TAMIFLU": 0.923082895666032, "TASIGNA": 1.1325549564748774, "TOZINAMERAN": 0.1411760116944492, "UMECLIDINIUM": 147.61474342621224, "VARENICLINE": 26.621213362331087, "VAXZEVRIA": 0.0139607879270525, "XOLAIR": 5.476101458511203, "ZYPREXA": 0.9225206397699496, "null": 1.5371880372590232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4231.json
index 68cdc5ca4af..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4231.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4231.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 213.77349202416715}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4232.json
index 0586a6420ef..123039ccc3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4232.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4232.json
@@ -1 +1 @@
-{"BUPIVACAINE": 264.4832023807302, "LINACLOTIDE": 6734.374033975497, "null": 1.2119986100173927}
\ No newline at end of file
+{"SPIKEVAX": 1.1507821949395145, "null": 0.1935758078915073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4233.json
index 63f61a46f00..864325fcdeb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4233.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4233.json
@@ -1 +1 @@
-{"IRON": 225.136020516175, "KEPPRA": 15.365046518605595, "OCEAN": 4167.916707069352, "PANTOPRAZOLE": 101.5500062207642, "TOVIAZ": 169.6004886034721}
\ No newline at end of file
+{"COMIRNATY": 0.1400501420860362, "CUBICIN": 47.62854443960199, "KEYTRUDA": 6.684185973198688, "null": 1.3822654475560263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4234.json
index 83ca1dbb5cc..44018a579e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4234.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4234.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 112.87100087956834, "null": 1.6169842601352595}
\ No newline at end of file
+{"ABASAGLAR": 1.5101718065486416, "ADENURIC": 4.995770764503242, "AERIUS": 5.620156441244753, "ALIMTA": 0.5938718380697929, "AMIKACIN": 9.349164823905468, "ANORO": 0.966835649164695, "APROVEL": 5.603570250181797, "ARANESP": 1.350721935318684, "ARAVA": 0.1466446031156119, "ARIPIPRAZOLE": 1.2652444308580162, "ARIXTRA": 6.687854768100896, "ATAZANAVIR": 1.0214443155649455, "AUBAGIO": 0.9415961546330556, "AVAMYS": 1.2231023793290643, "AZTREONAM": 19.18348230403525, "BIKTARVY": 0.9821568396026408, "BINOCRIT": 8.870304500094988, "BRILIQUE": 2.945562999894669, "BUDESONIDE": 14.715432877872876, "CANCIDAS": 7.270462614918485, "CASPOFUNGIN": 3.2641881468700875, "CELLCEPT": 0.3003362836364717, "CHOLESTAGEL": 30.398701899431316, "CICLOSPORIN": 0.38327116218889, "CIMZIA": 0.0971198745416629, "CLOPIDOGREL": 1.52616779325206, "COAPROVEL": 2.9159635776616866, "COMBIVIR": 2.550146602546409, "COMIRNATY": 0.0651838110886003, "COMPLEMENT": 41.24530569511127, "COSENTYX": 0.3969642753265995, "COTELLIC": 2.8094752618794923, "CUBICIN": 32.32341475709163, "CYMBALTA": 0.2328218989353529, "DAPTOMYCIN": 6.718209619446062, "DESLORATADINE": 3.844574625483778, "DEXAMETHASONE": 0.8365139946530613, "DIFICLIR": 20.724558211876207, "DUPIXENT": 4.676493960660832, "EBIXA": 5.388159224928923, "EFIENT": 3.867433900711243, "ELIQUIS": 0.6463605754886141, "EMTRICITABINE": 1.9281037733099768, "ENOXAPARIN": 2.7695082547512886, "ENTRESTO": 0.9878772164999752, "ENTYVIO": 1.420119839339271, "EPIVIR": 1.900993231872388, "ESOMEPRAZOLE": 3.799315730217822, "EUCREAS": 3.235380510740385, "EXJADE": 0.2882965946285032, "FASENRA": 2.9571784773485668, "FEBUXOSTAT": 3.658325672210787, "GANCICLOVIR": 1.740087660995837, "GARDASIL": 0.2923226534869342, "IBUPROFEN": 1.0434860107121753, "INCIVO": 4.810070668988482, "INSULIN": 0.9567845818800306, "IPILIMUMAB": 1.3433577119300888, "IRBESARTAN": 5.285994348254948, "ISENTRESS": 5.474973448983155, "JANUMET": 0.5811785007054137, "JANUVIA": 0.5583513118369791, "JARDIANCE": 0.4000888710981516, "KAFTRIO": 2.356874577628832, "KALETRA": 0.6865301905092122, "KEPPRA": 2.7058028366735174, "KEYTRUDA": 1.0264215691574388, "KIVEXA": 5.088487823700116, "LANTUS": 0.2640117481162348, "LEFLUNOMIDE": 1.1375089300963783, "LEMTRADA": 0.6052181296916175, "LEVETIRACETAM": 3.857571960361709, "LEVOFLOXACIN": 1.7067564134022752, "LOPINAVIR": 5.207396936186621, "LYRICA": 1.0623888549891318, "MABTHERA": 1.359091509757863, "MEPOLIZUMAB": 2.250464897874798, "METFORMIN": 3.779736757670315, "METHOTREXATE": 0.36275194441446, "MICARDIS": 1.767149510611126, "MIDAZOLAM": 1.329485095923417, "MIMPARA": 2.0786496488732835, "NEXAVAR": 0.3988076690668912, "NORVIR": 2.248148411607312, "NOVONORM": 10.36986542694903, "NOVORAPID": 0.3704556486204151, "NUCALA": 9.325180207289105, "OLANZAPINE": 1.6770510077857856, "OMALIZUMAB": 0.3492673777358818, "OPDIVO": 1.9180168858009168, "PANTOPRAZOLE": 7.1227566660689545, "PEGASYS": 0.3421517225073091, "PEGINTERFERON": 1.2568279784940963, "PEMBROLIZUMAB": 0.8131297984775548, "PLAVIX": 1.7686910453365, "PREGABALIN": 5.759221105372885, "PROTELOS": 19.64351038865956, "RASILEZ": 1.4649127173414238, "RENVELA": 31.80448542443745, "REVLIMID": 2.1857501146649487, "RIBAVIRIN": 0.6720151782710303, "RITUXIMAB": 0.5454118548971382, "ROACTEMRA": 2.520100570989864, "SIMPONI": 0.3007641744564909, "SPIKEVAX": 0.0343223773823901, "STELARA": 0.7806183417136623, "SUFENTANIL": 6.226639698414206, "TEMODAL": 2.084203745807542, "TOBRAMYCIN": 4.763391445780803, "TOZINAMERAN": 0.0548480451541474, "TRACLEER": 0.4751524000018183, "TRUVADA": 0.0806460852307725, "VAXZEVRIA": 0.0212052111225604, "VFEND": 1.4746274770275394, "VIMPAT": 1.9539342383704543, "VIRAMUNE": 7.086952592395356, "XARELTO": 1.120289152116781, "XOLAIR": 1.9128640759041449, "YERVOY": 1.1964238695878873, "ZELBORAF": 5.716945552966066, "ZYPREXA": 0.8811895868041952, "null": 2.798095003550069}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4235.json
index 6f0140e4b35..125412b5e11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4235.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4235.json
@@ -1 +1 @@
-{"BUPIVACAINE": 66.24372770902625, "CYMBALTA": 5.432190211167501, "FENTANYL": 11.508013788723003, "KEPPRA": 20.610864628454262, "LINACLOTIDE": 2690.8813664238464, "MIRABEGRON": 367.6303099999968, "null": 1.2774948409642946}
\ No newline at end of file
+{"AVAMYS": 69.15471068134116, "BUDESONIDE": 119.20021936773516, "MEPOLIZUMAB": 57.956206649939226, "null": 0.3668269403827185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4236.json
index dca4a0fb711..a3f1ae0b753 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4236.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4236.json
@@ -1 +1 @@
-{"PLAVIX": 66.67846209606256}
\ No newline at end of file
+{"COMIRNATY": 0.3883373535381157, "null": 1.1224606645002349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4237.json
index 047309c2b56..f5acdb16619 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4237.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4237.json
@@ -1 +1 @@
-{"null": 2.531466042797645}
\ No newline at end of file
+{"null": 0.7198687643182689}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4238.json
index 5e4decb3d34..4b8fa076fd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4238.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4238.json
@@ -1 +1 @@
-{"ELIQUIS": 15.21130207721149, "null": 1.0029216615858632}
\ No newline at end of file
+{"LEVETIRACETAM": 128.51419354834565, "null": 2.790893158746566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4239.json
index b02bf9b14c1..ace3016e298 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4239.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4239.json
@@ -1 +1 @@
-{"BUPIVACAINE": 49.881796170019705, "FENTANYL": 7.811672384566375, "IRON": 83.09099201631, "KEPPRA": 15.953362756460644, "MELATONIN": 54.33093490658237, "TOVIAZ": 59.44726748539614, "null": 1.515504378888737}
\ No newline at end of file
+{"COMIRNATY": 0.3882391959639035, "KEYTRUDA": 13.064842871226915, "PEMBROLIZUMAB": 70.55753608928401, "null": 0.340806842762972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/424.json
index 966810d4ccd..b9d66b94912 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/424.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/424.json
@@ -1 +1 @@
-{"AVANDAMET": 45.84325643231059, "AVANDIA": 25.75840700252757, "CLOPIDOGREL": 4.130656930717373, "INFLIXIMAB": 39.68660109588753, "JANUMET": 11.778053954653188, "JANUVIA": 7.077460816221555, "LANTUS": 3.13454567254831, "OPSUMIT": 6.684156862468332, "PLAVIX": 3.645819862662734, "TRACLEER": 8.806714440816204, "null": 1.1369053258094035}
\ No newline at end of file
+{"null": 2.74112677223756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4240.json
index d393a318551..75a846f5955 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4240.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4240.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 203.80122711198308}
\ No newline at end of file
+{"ANORO": 163.87951462525564, "APIXABAN": 23.08455307385516, "AZATHIOPRINE": 23.013738876760307, "BENRALIZUMAB": 13.701868092712829, "BUDESONIDE": 6.105644701946265, "COMIRNATY": 0.0877242638086899, "FASENRA": 38.22006720967221, "LEVOFLOXACIN": 0.9203943901810738, "MEPOLIZUMAB": 5.610060936559059, "METHOTREXATE": 8.401074238769791, "NUCALA": 10.79423536000895, "OMALIZUMAB": 8.364438316906998, "SPIKEVAX": 0.0475713386970105, "XOLAIR": 16.741397252534668, "null": 2.863875826586399}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4241.json
index 2f1d1e4ada0..665fa8728c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4241.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4241.json
@@ -1 +1 @@
-{"BUPIVACAINE": 158.40017261745592, "FENTANYL": 12.44916203590515, "null": 1.584050226813276}
\ No newline at end of file
+{"null": 1.880737104990534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4242.json
index 18f13c12dad..f398f8b77ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4242.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4242.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 453.741438065735}
\ No newline at end of file
+{"COMIRNATY": 0.1615785568213438, "EMPAGLIFLOZIN": 54.64717491053017, "METHOTREXATE": 77.50412027845114, "null": 2.08969201530414}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4243.json
index b0f488ba817..a549e8dae33 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4243.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4243.json
@@ -1 +1 @@
-{"null": 4.705583054188087}
\ No newline at end of file
+{"ADCIRCA": 54.69795916037025, "COMIRNATY": 0.3923717261289631, "GARDASIL": 9.935904510541976, "XOLAIR": 6.299321516974139, "null": 3.324041273417324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4244.json
index b0537d2dbc0..9fa39b5b195 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4244.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4244.json
@@ -1 +1 @@
-{"null": 1.561918659840594}
\ No newline at end of file
+{"null": 3.260400439880456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4245.json
index 28a7500e9a0..b9477101d8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4245.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4245.json
@@ -1 +1 @@
-{"AVONEX": 765.3409833463292, "CYMBALTA": 11.140578576166847, "KEPPRA": 20.377184296984304}
\ No newline at end of file
+{"ADCIRCA": 10.657785189773763, "CLOPIDOGREL": 1.873072172061186, "COMIRNATY": 0.0792977073178454, "CUBICIN": 682.0369350743701, "ELIQUIS": 0.4520776538102466, "ENTYVIO": 3.9566100429229296, "KEYTRUDA": 0.9688973293062364, "LEVOFLOXACIN": 4.488350824737814, "METHOTREXATE": 11.605386980028914, "PLAVIX": 2.718442840465225, "SIMPONI": 2.089514630422693, "STELARA": 2.5407496572231087, "XOLAIR": 1.0835798256126834, "null": 1.8483496835333957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4246.json
index 4c4e3439e50..40aaf4b45af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4246.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4246.json
@@ -1 +1 @@
-{"AVANDAMET": 72.10628156499364, "AVANDIA": 67.76721455366767, "ENTRESTO": 7.521236884866854, "GALAFOLD": 95.1580602402994, "SILDENAFIL": 25.749770746545995, "null": 1.1778209078130029}
\ No newline at end of file
+{"CUBICIN": 641.1133176788422, "LEVOFLOXACIN": 7.279558311811068, "null": 2.0247213477732986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4247.json
index f488584e472..589c5f56a5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4247.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4247.json
@@ -1 +1 @@
-{"null": 1.7436960170364368}
\ No newline at end of file
+{"null": 0.9162413242697972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4248.json
index 48dd81a6ce4..0e7d8a4cb83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4248.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4248.json
@@ -1 +1 @@
-{"null": 5.338774251570324}
\ No newline at end of file
+{"null": 0.6572227330518101}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4249.json
index 9c7c864dcc6..82a03d225b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4249.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4249.json
@@ -1 +1 @@
-{"null": 1.932247952740592}
\ No newline at end of file
+{"null": 0.3884546592643642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/425.json
index 496d7ef9f62..9368c6894d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/425.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/425.json
@@ -1 +1 @@
-{"VOTRIENT": 41.77293056198687, "null": 1.229809544296353}
\ No newline at end of file
+{"PANTOPRAZOLE": 101.85420501229297, "null": 1.8792931812456068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4250.json
index cabb0f4689f..05e1c890986 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4250.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4250.json
@@ -1 +1 @@
-{"ABILIFY": 16.75123112795543, "AZILECT": 64.74050840141537, "CARBIDOPA": 86.50550160601635, "CYMBALTA": 1.2380854653375486, "ENTACAPONE": 92.71688525003526, "KEPPRA": 1.888277363799665, "LEVODOPA": 257.6020699368528, "NEUPRO": 196.8637368244121, "RASAGILINE": 882.9245621992858, "ROTIGOTINE": 1163.3644995102547, "SIFROL": 477.8563340275925, "STALEVO": 33.91390444203331, "null": 1.6717602350372165}
\ No newline at end of file
+{"COMIRNATY": 1.539237318166838, "COSENTYX": 4.006872857572628, "ENBREL": 3.693440757446758, "SPIKEVAX": 0.8400891681550335, "TOZINAMERAN": 0.8866137330614968, "TRUVADA": 1.2579161907156309, "VAXZEVRIA": 0.526602963057611, "ZOSTAVAX": 4.42593629355172, "null": 0.9944976284143268}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4251.json
index ad850bdcecb..52ee7c3b19c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4251.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4251.json
@@ -1 +1 @@
-{"ABILIFY": 12.273953157695423, "ARIPIPRAZOLE": 5.238671227295008, "BRINTELLIX": 6.137068463420575, "BUDESONIDE": 2.3161080491186343, "CHAMPIX": 7.822267655108584, "CYMBALTA": 2.909442587366036, "ENTACAPONE": 51.4465266678604, "KAFTRIO": 16.262998645444394, "KEPPRA": 4.837932344503909, "LATUDA": 12.267298597575476, "LEVETIRACETAM": 10.038878560968842, "MELATONIN": 19.403227347769885, "OLANZAPINE": 8.136177134481038, "null": 3.0792959174125096}
\ No newline at end of file
+{"ARIXTRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4252.json
index 8a946591177..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4252.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4252.json
@@ -1 +1 @@
-{"ABILIFY": 8.930202475636476, "ANORO": 10.108351672173235, "BRIVIACT": 25.330867579726952, "CIMZIA": 10.5101716106299, "ELIQUIS": 2.6179181648591188, "FASENRA": 15.378595623875018, "JANUMET": 8.276422176835913, "JANUVIA": 13.834756738896036, "KEPPRA": 2.144046934425343, "KEYTRUDA": 2.4229405796487637, "TRELEGY": 30.973314589837297, "VIMPAT": 15.869477421325698, "null": 2.596063513114127}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4253.json
index 664bbfb8775..0bb772ae37a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4253.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4253.json
@@ -1 +1 @@
-{"null": 1.4255256721462233}
\ No newline at end of file
+{"AZARGA": 1291.3632998222286, "AZOPT": 844.2336356273643, "IBUPROFEN": 8.183632570142185, "LEVOFLOXACIN": 9.237013685439615, "null": 2.1125706440905008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4254.json
index cd50388220a..0fc8144cf13 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4254.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4254.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 22.19814327820291, "CLOPIDOGREL": 2.095703131777292, "FENTANYL": 17.05233650416307, "IBUPROFEN": 6.001305690065143, "PREGABALIN": 16.694727020514254, "SUBOXONE": 8.553593895333734, "SUFENTANIL": 40.11323721734267, "null": 4.13524740584665}
\ No newline at end of file
+{"NEXAVAR": 10.292004997085044, "null": 1.5274602407699822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4255.json
index 63b10eddd66..66f1f5d7007 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4255.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4255.json
@@ -1 +1 @@
-{"EYLEA": 687.0395364038268, "null": 1.099498120056937}
\ No newline at end of file
+{"null": 2.328626407465836}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4256.json
index 139a8a9b8e2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4256.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4256.json
@@ -1 +1 @@
-{"null": 3.487298748185552}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4257.json
index cbd99deb94e..6efb94c6cca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4257.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4257.json
@@ -1 +1 @@
-{"ANTIBIOTICS": 96.89138874033952, "CHAMPIX": 3.18032499056214, "CYMBALTA": 1.7834659416352328, "TOZINAMERAN": 1.0577444578133464, "ZYPREXA": 3.658862029781966, "null": 2.5877278709604017}
\ No newline at end of file
+{"null": 5.170063992308876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4258.json
index 774dc4abace..d561a1a9587 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4258.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4258.json
@@ -1 +1 @@
-{"ALIMTA": 1.752849207914402, "APROVEL": 5.43385379790176, "ARIPIPRAZOLE": 1.4028471845955592, "ASPARAGINASE": 8.68460498726035, "BRINTELLIX": 3.569476725042221, "COAPROVEL": 15.095216283796704, "CYMBALTA": 7.860906762142711, "CYTARABINE": 2.17238025138904, "DEXAMETHASONE": 1.4471527557874582, "DOXORUBICIN": 2.170291675945544, "DULOXETINE": 9.481040121298316, "EMEND": 6.334088484527775, "ESOMEPRAZOLE": 4.68695369620357, "EXFORGE": 1.7455451850590982, "IRBESARTAN": 3.073558305953341, "JEVTANA": 3.752455165499272, "KEPPRA": 2.8464149906105067, "KEYTRUDA": 2.023099702122953, "LEVETIRACETAM": 2.180918036870101, "MICARDISPLUS": 15.451594909593137, "MIDAZOLAM": 1.7576072795255986, "OLANZAPINE": 4.98296706928932, "OPDIVO": 1.2591354584771133, "PANTOPRAZOLE": 3.623630397504133, "RIVASTIGMINE": 127.0636169739774, "TAMIFLU": 1.1202212580549378, "TOVIAZ": 2.4605908820595768, "VFEND": 5.696799664278896, "ZYPREXA": 4.491925364503508, "null": 4.042461779876607}
\ No newline at end of file
+{"COMIRNATY": 0.7374772485510945, "FORXIGA": 12.31966695247284, "ISENTRESS": 42.31611709354543, "JARDIANCE": 7.485675490815025, "KAFTRIO": 26.1945148525824, "SPIKEVAX": 0.8249002997244259, "TOZINAMERAN": 0.6806299506525243, "VAXZEVRIA": 0.2487714244408067, "null": 0.9749927077697632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4259.json
index 7dd52361ffa..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4259.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4259.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.6575068512328854, "ABILIFY": 2.3380392031523503, "ADCETRIS": 1.2547526346549394, "AIMOVIG": 1.4636018083544513, "ANORO": 1.376671788721341, "APIDRA": 1.574708435265094, "BELIMUMAB": 1.509405929309169, "BENLYSTA": 6.838151745977968, "BETMIGA": 2.651116169060718, "BUPRENORPHINE": 1.6280172346405817, "CABOMETYX": 3.311076164933438, "CABOTEGRAVIR": 3.686343955482892, "CANAGLIFLOZIN": 2.8294218193359, "CIMZIA": 1.467364770829655, "CINRYZE": 26.81581071894328, "COSENTYX": 6.250176592315128, "DAPAGLIFLOZIN": 1.9735577117723824, "DOLUTEGRAVIR": 1.624831225202911, "DULAGLUTIDE": 2.350372917760858, "ELLAONE": 6.445725806671893, "EMEND": 1.2871233554512147, "ENTRESTO": 3.678077890179571, "ENTYVIO": 1.2298286187743526, "ERENUMAB": 1.1853096784765729, "EVRA": 7.4254628499864515, "EYLEA": 2.0418929123166327, "FAMPYRA": 1.2308213378055934, "FASENRA": 4.257741415837461, "FORSTEO": 1.3753610500927476, "GALAFOLD": 4.172117018832758, "GARDASIL": 3.5903435834293447, "HUMALOG": 1.1053708724310394, "HUMIRA": 1.5478583172008855, "HYQVIA": 3.5836123627091583, "INFLECTRA": 3.60955537663064, "INFLIXIMAB": 2.141386733512766, "INSULIN": 1.4563255845097525, "INVEGA": 2.195184496674329, "JAKAVI": 2.3987360299331915, "JANUMET": 13.118898365690043, "JANUVIA": 1.5653216076352452, "JORVEZA": 8.710665684569504, "KEPPRA": 1.2252836191589391, "KEYTRUDA": 3.30449519163866, "KISQALI": 1.8606159144954135, "LANTUS": 4.0772653104309216, "LIXIANA": 1.5054252106748025, "LONSURF": 8.573613017843925, "LUTATHERA": 3.8027043099293487, "MEPOLIZUMAB": 4.133627515147525, "MISOPROSTOL": 7.772847748160262, "NEULASTA": 1.281637749547784, "NOXAFIL": 2.6324839157921502, "NUCALA": 3.2746659512288554, "OMALIZUMAB": 3.4153061409529117, "OZEMPIC": 1.2470372356470587, "PANTOPRAZOLE": 1.9967398298603185, "PASIREOTIDE": 8.664967430745136, "PEMBROLIZUMAB": 4.670820252626418, "PLEGRIDY": 1.531236505429215, "POTELIGEO": 4.570649351721388, "PROLIA": 1.6522708785987608, "PROPRANOLOL": 1.1328361403045748, "QUTENZA": 2.922072863967962, "RELVAR": 1.059496652344856, "REMICADE": 1.2270726265724476, "REPAGLINIDE": 3.0792771849677902, "ROTATEQ": 3.1752599169597207, "RYBELSUS": 3.2822261274796354, "SACITUZUMAB": 5.937126614629556, "SAMSCA": 1.8583001680742224, "SAXENDA": 3.6130814909044062, "SHINGRIX": 2.5767991977469977, "SIMPONI": 9.3386349855681, "SOLIRIS": 6.142843112685863, "SOMAVERT": 7.913379590326489, "STELARA": 7.030303408050163, "SUBOXONE": 4.8563861509507165, "SYCREST": 1.997515159348082, "SYNAGIS": 2.3163840425681075, "TOUJEO": 7.017598988595349, "TOZINAMERAN": 7.140304059688646, "TRELEGY": 1.4592968701377889, "TREMFYA": 3.3051573197221056, "TRULICITY": 2.8026005234367504, "TWINRIX": 4.583854680225767, "VALSARTAN": 5.080456742271332, "VECTIBIX": 1.1178325801279008, "VELMETIA": 2.2003833446325527, "VELTASSA": 6.70791792925514, "VICTOZA": 1.004804053326495, "VIMPAT": 3.0583068445172046, "XARELTO": 1.2454400923363715, "XOLAIR": 1.600535744468413, "XTANDI": 1.6899795161183495, "XYREM": 1.1723758452636637, "ZYPADHERA": 1.255179522120216}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/426.json
index dd074b8d170..495fc394388 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/426.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/426.json
@@ -1 +1 @@
-{"VOTRIENT": 172.01202449436644}
\ No newline at end of file
+{"null": 2.9341242589086303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4260.json
index b9dd078c473..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4260.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4260.json
@@ -1 +1 @@
-{"SUBOXONE": 170.14412666027445}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4261.json
index 54c601fa76a..4dc72849716 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4261.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4261.json
@@ -1 +1 @@
-{"BUMETANIDE": 1443.7830846389747}
\ No newline at end of file
+{"ELIQUIS": 17.18410907223282, "null": 0.5983845148152901}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4262.json
index 9604d0aee10..2e09ccc80e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4262.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4262.json
@@ -1 +1 @@
-{"null": 1.329258115524737}
\ No newline at end of file
+{"ARIPIPRAZOLE": 126.89755851371504, "null": 0.636331053505638}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4263.json
index 34dfebc7045..413a02be5d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4263.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4263.json
@@ -1 +1 @@
-{"null": 2.8865086325763807}
\ No newline at end of file
+{"ABATACEPT": 4.410548357968583, "ARAVA": 2.042677559216824, "CICLOSPORIN": 1.0678077909034287, "CLOPIDOGREL": 6.025020845618826, "COMIRNATY": 0.2923569092198337, "ELIQUIS": 0.764444056070665, "ENBREL": 2.0148652200839265, "FORXIGA": 3.0759988974532604, "GARDASIL": 0.7947140228674578, "JANUMET": 2.1301982611662367, "JARDIANCE": 1.3792319040131875, "KEPPRA": 1.5457823574519092, "METHOTREXATE": 4.27201635702827, "PEGASYS": 1.277874612722235, "PLAVIX": 1.3860838723501288, "SPIKEVAX": 0.220617620521023, "SUTENT": 0.8429112870824138, "TOZINAMERAN": 0.2806065970947418, "VAXZEVRIA": 0.2331708151521508, "XELJANZ": 1.024972142130188, "null": 1.5342275341474074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4264.json
index 9ebdfcbdf7d..c6fa30bd139 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4264.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4264.json
@@ -1 +1 @@
-{"ELIQUIS": 14.804861072022629, "PLAVIX": 11.315875907389444, "null": 1.183098977607001}
\ No newline at end of file
+{"COMIRNATY": 0.2230813727731898, "null": 2.488477663376592}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4265.json
index 61bc331c005..354c7b90694 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4265.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4265.json
@@ -1 +1 @@
-{"SUTENT": 5.733813722048219, "null": 1.3357237382070768}
\ No newline at end of file
+{"XTANDI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4266.json
index e1d89c0095d..39d530526d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4266.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4266.json
@@ -1 +1 @@
-{"null": 1.2342757628256125}
\ No newline at end of file
+{"COMIRNATY": 0.1960915523609841, "ROACTEMRA": 18.873220888636816, "null": 1.5944988261027135}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4267.json
index 800a285fd6e..6dede4261ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4267.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4267.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 10.905387006102924, "BUPRENORPHINE": 6.051110483875157, "CHAMPIX": 1.0456359670577, "CYMBALTA": 2.408312008833648, "DEXAMETHASONE": 1.390147487935648, "GARDASIL": 1.3824418331560175, "HUMALOG": 2.6164135954225056, "KALETRA": 2.9995746638831653, "KEPPRA": 1.2886451687484213, "LANTUS": 3.982307829384337, "OLANZAPINE": 2.9484518453631647, "PEGASYS": 1.539540498031556, "SUBOXONE": 2.9157113473327385, "TAMIFLU": 4.829033897068582, "ZYPADHERA": 14.516592500646311, "ZYPREXA": 2.902030991375747, "null": 2.128198867886594}
\ No newline at end of file
+{"DEXAMETHASONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4268.json
index a0f55a67f9d..6088ce274cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4268.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4268.json
@@ -1 +1 @@
-{"GARDASIL": 4.899971239737133, "ROTATEQ": 15.284630442685868, "SHINGRIX": 109.4928881444932, "SPIKEVAX": 1.873035136962963, "TWINRIX": 22.85280426762973, "VAXZEVRIA": 4.794000916064215}
\ No newline at end of file
+{"LACOSAMIDE": 198.26593683567603, "LEVETIRACETAM": 65.6393091691687, "null": 0.4628365705705682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4269.json
index 24a79c498b1..234b8142c09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4269.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4269.json
@@ -1 +1 @@
-{"ACE": 54.16071193622556, "AIMOVIG": 1.2709897146314169, "AUBAGIO": 4.979825168622008, "BETMIGA": 4.789270373588477, "CYMBALTA": 1.6231112744202305, "FAMPYRA": 4.922101222891159, "FORSTEO": 2.057538055118504, "FORXIGA": 3.490767767671846, "GARDASIL": 1.27405653967696, "JARDIANCE": 2.8550284174350056, "KEPPRA": 1.0226246356718407, "KYMRIAH": 2.358406836584282, "LYRICA": 1.0152762339328192, "MELATONIN": 8.421779777177536, "OLANZAPINE": 2.407502371630319, "OXYBUTYNIN": 12.2114186684251, "TOVIAZ": 6.274686445724933, "XTANDI": 2.3260090743721022, "YESCARTA": 13.276346641173468, "ZOSTAVAX": 1.6715559753475129, "ZYPREXA": 4.261679012117064, "null": 1.5388914798443634}
\ No newline at end of file
+{"ABACAVIR": 0.2098114887500129, "ABATACEPT": 4.123184214704286, "ABILIFY": 0.794312026057114, "ADALIMUMAB": 1.629125911604181, "AERIUS": 1.7174580229491796, "AFINITOR": 0.6269492618232324, "AIMOVIG": 6.548009661339111, "ALEMTUZUMAB": 0.410481616391992, "ALIMTA": 0.2911115951925465, "AMIKACIN": 0.7684578480454681, "APIDRA": 0.208631334512317, "APIXABAN": 0.1279405472461618, "APREMILAST": 10.010226227238338, "ARANESP": 0.2129772516924254, "ARIPIPRAZOLE": 0.1572865257893294, "ASPARAGINASE": 2.3727635501806965, "ATRIPLA": 0.0165400565101068, "AUBAGIO": 0.1767698897449347, "AVAMYS": 1.9620651648655043, "AVASTIN": 0.5624824340742992, "BEDAQUILINE": 1.5261111042594409, "BENLYSTA": 0.215589383947419, "BETAFERON": 1.0546256140113182, "BETMIGA": 0.8215617481706847, "BEXSERO": 1.489284969296795, "BIKTARVY": 1.2378046692284497, "BRILIQUE": 0.5288087377118158, "BRINTELLIX": 1.2779798821654291, "BRIVARACETAM": 11.911218636710496, "BRIVIACT": 8.227052707751023, "BUCCOLAM": 15.45352692017746, "BUPRENORPHINE": 0.245340232074824, "BUSULFAN": 0.7940194012422107, "BYETTA": 0.1606919931021526, "CABOMETYX": 0.2719650837596328, "CANCIDAS": 0.7904750023577848, "CANNABIDIOL": 7.822489278520348, "CAPECITABINE": 0.9715148688375213, "CELLCEPT": 0.5221555448217854, "CHAMPIX": 2.1944611036790267, "CICLOSPORIN": 0.7491642608699568, "CIMZIA": 0.142063769482307, "CIRCADIN": 3.9065289112923858, "COMBIVIR": 0.6217288097807108, "COMIRNATY": 0.5054138978973625, "COSENTYX": 0.1232936806091623, "CYMBALTA": 0.5696482317486709, "CYTARABINE": 0.2686931028721251, "DEXAMETHASONE": 0.3181174506079379, "DIACOMIT": 14.508609668481167, "EBIXA": 10.046585547440008, "ELIQUIS": 0.3880293985316139, "EMEND": 1.1025746723437884, "ENTRESTO": 0.1452039378209803, "ENTYVIO": 0.231850465902053, "EPIDYOLEX": 11.781796004675943, "ERLEADA": 1.2059756764843448, "ESOMEPRAZOLE": 0.6202175022887153, "EVENITY": 0.5262284833958575, "EXELON": 5.025424609617815, "EXFORGE": 0.3211205276557296, "FAMPYRA": 7.1586094707892265, "FENTANYL": 0.3308533956282787, "FORSTEO": 0.7328155236484329, "FORXIGA": 0.2159671080884982, "FYCOMPA": 9.16621615839612, "GARDASIL": 2.526118706123407, "HARVONI": 0.32919703697891, "HEMLIBRA": 1.703565690875214, "HIZENTRA": 0.2849859551766173, "HUMALOG": 0.3932866323631253, "HUMIRA": 0.4691331817570203, "IBUPROFEN": 0.2209621387341789, "INFANRIX": 3.900284836279887, "INLYTA": 0.473781745402647, "INOVELON": 11.840997356961102, "INVANZ": 6.104987061503228, "IRESSA": 0.888715855527153, "JAKAVI": 0.2992980999333866, "JANUVIA": 0.362355478830221, "JARDIANCE": 0.1501208530469137, "KAFTRIO": 1.3465254080803413, "KEPPRA": 13.629174147513815, "KEYTRUDA": 0.239734979941209, "LACOSAMIDE": 17.709001398372894, "LANTUS": 0.3776500377009595, "LATUDA": 0.4516451882838961, "LEMTRADA": 0.7405958552247086, "LENVIMA": 0.721775659826587, "LEVEMIR": 0.2321768356429383, "LEVETIRACETAM": 16.666419495506936, "LEVOFLOXACIN": 1.8182618399935184, "LYNPARZA": 0.5837450287274327, "LYRICA": 0.7672107406138303, "MEKINIST": 1.027900068128999, "METHOTREXATE": 0.1643921132765104, "MICARDIS": 0.2912870679716311, "MIDAZOLAM": 1.7077149529046525, "MIMPARA": 2.533047565713162, "MMRVAXPRO": 0.7109889995981103, "MODERNA": 0.2397120836105536, "NEXAVAR": 0.1670648012382234, "NIMENRIX": 1.2542381108962244, "NORVIR": 1.3098354001852133, "NOT": 0.5085915665012559, "NOVORAPID": 0.254825484775133, "NUCALA": 0.1224882180814399, "OLANZAPINE": 1.14677181000919, "OPDIVO": 0.2281123107492909, "PEGASYS": 0.4086654987866615, "PEGINTRON": 0.430975578281403, "PEMBROLIZUMAB": 0.4415030275279812, "PERAMPANEL": 15.057648403573708, "PLAVIX": 0.1460820308861601, "PREGABALIN": 1.3484465434465165, "PREVENAR": 1.518399441220321, "PROTELOS": 2.3252081227075263, "RINVOQ": 0.4501928629384794, "RISPERIDONE": 1.5406681232415074, "RITUXIMAB": 0.3210040668452198, "ROACTEMRA": 0.4646536906061267, "ROTATEQ": 0.874797422416226, "SAXENDA": 0.3136688340454197, "SHINGRIX": 0.2151197197994405, "SIMPONI": 0.2281481338163936, "SOVALDI": 0.7290071689446509, "SPIKEVAX": 0.2779525011855306, "SPINRAZA": 1.594047140977376, "STELARA": 0.4575199428396256, "STIVARGA": 0.3226769900769058, "SUBOXONE": 0.2997556144735644, "SUTENT": 0.2129160090159072, "TAGRISSO": 0.3420130899190224, "TAMIFLU": 1.3759652544676797, "TEMODAL": 2.5343123483670507, "TEMOZOLOMIDE": 1.0062329035437534, "TOZINAMERAN": 0.4540552836824202, "TWINRIX": 1.5990083915118187, "VAXZEVRIA": 0.3108818783165291, "VFEND": 1.1887275839678146, "VIAGRA": 0.4955241910017575, "VICTOZA": 0.2978493886846987, "VIGABATRIN": 5.661081061762026, "VIMPAT": 25.420998187503887, "VORICONAZOLE": 1.1247022628787613, "VOTRIENT": 0.2545189509743547, "XELJANZ": 0.07967113304312, "XOLAIR": 0.371442575654356, "XTANDI": 1.2597196716557812, "ZAVESCA": 5.036546526054486, "ZONISAMIDE": 11.425929562407545, "ZOSTAVAX": 0.0909464081850482, "ZYPADHERA": 0.944597306061421, "ZYPREXA": 1.3148201643029611, "null": 2.094474197764495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/427.json
index 0fead327524..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/427.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/427.json
@@ -1 +1 @@
-{"PEGINTERFERON": 70.14436932856873}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4270.json
index 7fbe9d055e3..04037c593e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4270.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4270.json
@@ -1 +1 @@
-{"AIMOVIG": 129.5628809387308, "NEULASTA": 91.83551177133874}
\ No newline at end of file
+{"KEPPRA": 42.56641176407645, "null": 1.9394105009784244}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4271.json
index ef9bf429ff2..5c510935964 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4271.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4271.json
@@ -1 +1 @@
-{"ARAVA": 1.344790199632345, "CICLOSPORIN": 2.3758669490067703, "CLOPIDOGREL": 2.9078052897758204, "ELIQUIS": 1.1564403822546734, "ENTRESTO": 2.2431440202247144, "HUMALOG": 5.079578110604515, "KEPPRA": 1.7729856347537751, "LANTUS": 2.18674080243988, "PLAVIX": 1.355980057278211, "XELJANZ": 1.111247499471606, "null": 2.5920021777620508}
\ No newline at end of file
+{"COMIRNATY": 0.5414023026875469, "KEPPRA": 15.358171505039556, "null": 1.7304229941594695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4272.json
index 840a45d772d..a881939296c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4272.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4272.json
@@ -1 +1 @@
-{"ABASAGLAR": 26.08744557641807, "ABILIFY": 1.1014457359038667, "ACTOS": 2.120190454793858, "ACTRAPID": 3.402394032769598, "ADENURIC": 1.777522929272323, "ADVATE": 1.86162470836304, "AERIUS": 1.5017010008802103, "AIMOVIG": 2.809875304302876, "ANORO": 1.1751217518856, "APIDRA": 5.788217640698246, "ARIPIPRAZOLE": 3.075388076211569, "AVAMYS": 1.0562002897295215, "BEDAQUILINE": 1.3360068199788733, "BENLYSTA": 1.575863476746004, "BETAFERON": 1.2841172787396125, "BRIDION": 4.576765028236026, "BUMETANIDE": 3.149264068794942, "BUPIVACAINE": 1.065130296135734, "BYDUREON": 12.117634579351042, "BYETTA": 1.913571862414922, "CANCIDAS": 2.364643035261509, "CARBIDOPA": 4.089893222747718, "CIMZIA": 1.17384969407112, "CLADRIBINE": 3.8544604396674607, "COLLAGENASE": 26.17725192161104, "COSENTYX": 4.586620865936073, "DESLORATADINE": 3.005280615616549, "DEXMEDETOMIDINE": 3.450575076430014, "DULAGLUTIDE": 8.015056903867183, "EFIENT": 4.010552341133006, "EMPAGLIFLOZIN": 1.3347990922727486, "ENTACAPONE": 2.009071232631149, "ENTRESTO": 2.03495480429601, "ENTYVIO": 1.6724517985854748, "EVENITY": 4.0870254340427525, "EXFORGE": 1.8550895650368704, "EYLEA": 1.431788590068661, "FASLODEX": 1.032492297314888, "FIASP": 2.7544054038301087, "FORSTEO": 1.0200979976052285, "GALVUS": 2.523397623914536, "GLUCAGON": 6.476510556395466, "GONALF": 18.38893238001584, "HUMALOG": 17.720115081805087, "HYQVIA": 4.456709770838998, "IMBRUVICA": 3.8633513052893433, "INFLIXIMAB": 1.5136792715684346, "INSULIN": 7.256820448805883, "INVOKANA": 5.309192184949658, "JAKAVI": 1.2458069245750958, "JANUMET": 4.012508839937042, "JANUVIA": 1.113265926093038, "KEPPRA": 1.6212964125248956, "KESIMPTA": 1.2507901738198677, "KEYTRUDA": 1.3734621797040945, "LANTUS": 2.9443627198476, "LEVEMIR": 2.441650830376014, "LIPROLOG": 41.996423895927954, "LIXIANA": 20.41426748653862, "LYUMJEV": 22.27189997292105, "MEKINIST": 1.1503835653129653, "MELATONIN": 1.134058967601066, "MIDAZOLAM": 1.4057698995644607, "MULTAQ": 1.108895203274552, "NEULASTA": 2.5005617850355657, "NEVANAC": 7.133756729011886, "NOVORAPID": 3.7889825724727375, "NOXAFIL": 5.624872202858161, "OMALIZUMAB": 2.112311293662732, "OMNITROPE": 17.005229286481775, "OVITRELLE": 4.398355316929645, "OXYBUTYNIN": 1.1566490499937505, "PEMBROLIZUMAB": 1.2226940525971597, "PUREGON": 21.50022029979359, "RASBURICASE": 8.514772546174397, "RELVAR": 1.3179002255306835, "REVATIO": 1.3797923743706724, "SAMSCA": 3.77453488412448, "SAXENDA": 1.0970944677069436, "SIFROL": 1.3053675367072646, "SIMPONI": 3.3989102635379957, "SOLIRIS": 8.97936764452443, "SOMATROPIN": 1.4762573556592733, "STALEVO": 2.822161459869556, "STELARA": 2.2632884017835764, "TICAGRELOR": 2.1559789812340373, "TOUJEO": 5.018029843012827, "TRELEGY": 3.798670078725134, "TREMFYA": 1.4786383248556287, "TRESIBA": 2.783135611353261, "TRULICITY": 5.929511581967992, "VALSARTAN": 1.5931883687565471, "VIAGRA": 3.2826734037158976, "VIMPAT": 1.472023026220562, "XARELTO": 2.4655129228295745, "XOLAIR": 1.4460696298929272, "ZOSTAVAX": 1.6135165892192582, "ZYPADHERA": 1.0717381064502771, "null": 1.9328678865650155}
\ No newline at end of file
+{"LEVETIRACETAM": 111.82760703308053, "null": 1.2754798698693273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4273.json
index d23885a05df..425edd19760 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4273.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4273.json
@@ -1 +1 @@
-{"ACTRAPID": 27.30343797426918, "AIMOVIG": 11.13212766531186, "APIDRA": 18.20653141122177, "ARANESP": 1.3367243023971092, "BETAFERON": 15.98675005858739, "BYDUREON": 55.14875262704864, "BYETTA": 3.9729771557288247, "COSENTYX": 5.801520629896028, "FASENRA": 14.852070981448565, "FIASP": 86.41306673308985, "HUMALOG": 1.0316081577882634, "INSULATARD": 23.117799935883717, "INSULIN": 3.615381078273148, "KESIMPTA": 8.448579496906097, "LANTUS": 15.015704812605469, "LEVEMIR": 46.90545637174282, "NEULASTA": 5.448923004220324, "NOVORAPID": 80.0238247811495, "OMNITROPE": 80.89170409175007, "OPSUMIT": 1.0963926106164514, "PLEGRIDY": 11.84875348819214, "SAXENDA": 8.670079993897534, "SIMPONI": 1.584248412418699, "TOUJEO": 28.157920482205046, "TRESIBA": 60.87053935262371, "VICTOZA": 3.2255219113000813, "null": 1.3960716008246323}
\ No newline at end of file
+{"null": 0.9518920967503458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4274.json
index 9b8bcb00fe1..109c1f71d2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4274.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4274.json
@@ -1 +1 @@
-{"NOVORAPID": 31.850682159709184, "null": 2.923384706208534}
\ No newline at end of file
+{"COMIRNATY": 0.8543162640245086, "null": 1.1042497054935116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4275.json
index a0b74ff869e..1776a95423d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4275.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4275.json
@@ -1 +1 @@
-{"CINRYZE": 62.40536052352757, "DARZALEX": 12.651436699663108, "FENTANYL": 2.596427325467257, "HIZENTRA": 7.367623049050164, "HUMAN": 18.415175313121495, "IBUPROFEN": 18.919630755593754, "LEMTRADA": 24.46263347946997, "MIDAZOLAM": 11.222394195799463, "PRIVIGEN": 37.95988970092924, "null": 3.412071858392461}
\ No newline at end of file
+{"null": 6.244641060353657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4276.json
index e35b15fec31..03e6aa80ef8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4276.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4276.json
@@ -1 +1 @@
-{"ABASAGLAR": 7.1564066121743215, "AMINOSALICYLIC": 20.628353497619106, "BEDAQUILINE": 106.92682378638328, "BENLYSTA": 1.2388680034345445, "CIRCADIN": 7.978143020267403, "DELAMANID": 93.08773083028922, "DELTYBA": 48.88141291747056, "DENOSUMAB": 5.003583658567151, "DULOXETINE": 1.1661450306372838, "EPCLUSA": 4.173362157845683, "ESOMEPRAZOLE": 2.3999916659435976, "FORSTEO": 15.616738779076888, "HARVONI": 3.625035421755349, "HUMALOG": 9.035979882442422, "HYDROCORTISONE": 2.0664840836190974, "IBUPROFEN": 2.20232104615282, "INFLIXIMAB": 4.645671658960571, "INSULIN": 2.2071278027033023, "LEMTRADA": 4.583118031605791, "LONSURF": 1.8300046587667165, "MELPHALAN": 7.582793937870976, "NEVANAC": 26.282126748301376, "NUCALA": 1.8544685083445955, "PEGINTERFERON": 1.1175205296999655, "PLAVIX": 1.2570547925030024, "QUTENZA": 12.614906158993572, "RAPISCAN": 28.680268685146057, "RIBAVIRIN": 1.411829971152063, "SOVALDI": 6.3377282494176175, "null": 3.729277548026035}
\ No newline at end of file
+{"null": 4.045079320151362}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4277.json
index 0f03a1c2ec4..73cba68281e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4277.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4277.json
@@ -1 +1 @@
-{"HUMALOG": 7.7615260384409615, "NOXAFIL": 121.41060628921166, "null": 3.177754976232754}
\ No newline at end of file
+{"NUTROPIN": 882.160968263104, "SOMATROPIN": 722.4450930132522, "null": 4.127760147563786}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4278.json
index 36fd50f6939..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4278.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4278.json
@@ -1 +1 @@
-{"HUMALOG": 25.88890783753506, "null": 2.127358162107789}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4279.json
index 8bf85804237..2cc021ad2da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4279.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4279.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.5592137227557354, "AIMOVIG": 6.444768777197345, "APIDRA": 1.4141278128333166, "APREMILAST": 4.563710557295238, "ARANESP": 15.691171974007732, "ARAVA": 1.410537769306526, "ATAZANAVIR": 1.6783600294919694, "BONVIVA": 1.8699715385855769, "BORTEZOMIB": 1.346479391873805, "BUPIVACAINE": 8.87393198142919, "BUPRENORPHINE": 1.795362858016836, "CELLCEPT": 2.466737205296296, "CLOPIDOGREL": 1.1270831723876409, "COSENTYX": 3.514905890379844, "DACLIZUMAB": 48.17924502154337, "DARBEPOETIN": 54.897210869561945, "DOXORUBICIN": 1.479284256269692, "ENOXAPARIN": 1.63707995553401, "EVENITY": 1.8890922397004468, "FASLODEX": 1.7139418152358177, "FENTANYL": 11.544105258675051, "FLUTICASONE": 10.593128999116129, "GANCICLOVIR": 1.986395058704528, "GARDASIL": 2.1604787777969023, "HUMALOG": 1.9116402987145933, "HYDROCORTISONE": 2.4767807809314366, "ISENTRESS": 3.946916895007422, "KEPPRA": 1.330258586142028, "LACOSAMIDE": 3.531745660410877, "LANTUS": 1.0158260495285991, "LEVETIRACETAM": 2.565387640515437, "MELATONIN": 3.908664358311025, "MELPHALAN": 7.8080470551423025, "MENVEO": 1.8361495135762087, "MIDAZOLAM": 4.741102060308593, "MIRABEGRON": 8.5014818066818, "NEULASTA": 1.1073710955921496, "NIMENRIX": 1.9344531698909573, "NOT": 1.340972433947841, "NOXAFIL": 3.450011556572698, "ORGALUTRAN": 21.48588750191, "ROTATEQ": 1.2715422325118722, "RUCONEST": 6.665687103122151, "SHINGRIX": 4.319765846356616, "SOMAVERT": 16.851669547281585, "STELARA": 2.516594297263296, "SUBOXONE": 2.0722922078997, "SUFENTANIL": 2.829203323601296, "SYCREST": 23.306713323462887, "TOBRAMYCIN": 3.3041985821778623, "TREMFYA": 2.45250134069794, "TRULICITY": 1.5611877603453896, "XOLAIR": 3.1794267996872017, "ZOSTAVAX": 4.049389258655312, "ZYPADHERA": 2.897577996630229, "null": 1.9789121046347928}
\ No newline at end of file
+{"EYLEA": 33.33584119321566, "GANCICLOVIR": 81.73674680202016, "ZOSTAVAX": 31.42636889202153, "null": 0.6688289048740712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/428.json
index fe6a21ce105..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/428.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/428.json
@@ -1 +1 @@
-{"null": 12.43575419658052}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4280.json
index 76dd16d6b34..9ef829a0161 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4280.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4280.json
@@ -1 +1 @@
-{"BUDESONIDE": 106.1072779793699, "MELATONIN": 888.8504623211425}
\ No newline at end of file
+{"ADCIRCA": 63.65494520700914, "APIDRA": 20.25030887523095, "COMIRNATY": 0.9859858607858032, "ENBREL": 11.975934621469198, "SPIKEVAX": 0.4689273842857489, "VAXZEVRIA": 0.6829205199404603, "null": 0.2742775628294968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4281.json
index 2b11c2308aa..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4281.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4281.json
@@ -1 +1 @@
-{"ABASAGLAR": 4.18889015468786, "ABILIFY": 33.11811341749913, "AERIUS": 5.567778954914356, "ALEMTUZUMAB": 2.082442139972103, "ARIPIPRAZOLE": 53.62855523011491, "BIKTARVY": 4.289390165041169, "BRINTELLIX": 10.064717422334356, "BYDUREON": 4.506957210023666, "BYETTA": 1.4255285658059749, "CHAMPIX": 5.760277069053683, "CYMBALTA": 1.5399888461440498, "DESLORATADINE": 8.575065830098017, "DULOXETINE": 1.9088400256210845, "ELLAONE": 5.277451658542609, "ESOMEPRAZOLE": 2.501307115515281, "FORXIGA": 1.704493208203767, "FYCOMPA": 4.068681134055331, "IBRANCE": 1.0366684297303106, "INSULIN": 3.617582583129311, "JAKAVI": 2.3640481543499825, "JARDIANCE": 2.000831254515014, "LATUDA": 7.884965215555664, "LEMTRADA": 2.0815903969135383, "LYRICA": 2.715201198991129, "OLANZAPINE": 9.939609644550854, "RYBELSUS": 7.14137344115537, "SAXENDA": 14.291121642029738, "SOMATROPIN": 10.64671010133172, "SPINRAZA": 2.183575142400596, "SYCREST": 13.876496757354449, "TRULICITY": 2.629854708006699, "VICTOZA": 2.8510786813976363, "XELJANZ": 1.3641344756340683, "ZYPREXA": 18.71879465352872, "null": 1.1842579042978598}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4282.json
index fa2ab88d870..6dc05cf4b49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4282.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4282.json
@@ -1 +1 @@
-{"AVAMYS": 4.520626220632452, "CELLCEPT": 2.626672810439041, "FENTANYL": 7.792482361240531, "INCRUSE": 31.689351932243348, "KAFTRIO": 10.38566273672922, "LEVETIRACETAM": 3.764786053933884, "MEPOLIZUMAB": 21.032245913482697, "MIDAZOLAM": 9.80254338599024, "NUCALA": 2.8277202722080066, "OLANZAPINE": 3.335935127303889, "OMALIZUMAB": 8.76056365018181, "OPSUMIT": 2.9277141974958, "ORKAMBI": 40.84965511716271, "SPINRAZA": 32.878367472672025, "SYNAGIS": 17.760013140355337, "TRELEGY": 9.787910372809533, "UMECLIDINIUM": 73.64419455231749, "XOLAIR": 1.8646455167103824, "null": 1.5756102504653875}
\ No newline at end of file
+{"ABILIFY": 0.1371705449300125, "ADCIRCA": 2.460733512122954, "ADEMPAS": 1.9946167066311271, "ADVATE": 1.8625145005966728, "AERIUS": 1.972635004066561, "AFINITOR": 2.6563495417761334, "AIMOVIG": 0.1946330672351269, "ALEMTUZUMAB": 0.2918425319793861, "ALIMTA": 1.5757586052597663, "ALISKIREN": 0.8427301521417356, "AMBRISENTAN": 3.0098741339023487, "AMIKACIN": 0.4560400423564594, "AMINOSALICYLIC": 0.1266734652535013, "APIXABAN": 0.7746893548857537, "APROVEL": 0.8792369385310645, "ARANESP": 0.6297577190475192, "ARAVA": 0.159130094176659, "ARIXTRA": 1.623601759363905, "ASPARAGINASE": 0.1966196218065102, "AUBAGIO": 0.1040276604438631, "AVAMYS": 5.309963277871624, "AVASTIN": 3.3649741178406183, "AXITINIB": 1.0961751188611952, "AZATHIOPRINE": 0.1929851549828778, "BENLYSTA": 0.2447108569389608, "BETMIGA": 1.1048333585584305, "BEVACIZUMAB": 5.929418028509372, "BOCEPREVIR": 1.474611925274038, "BONVIVA": 0.4765257036611464, "BRAFTOVI": 0.2052582205174852, "BRILIQUE": 20.7448313995927, 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0.5118310254242591, "NINLARO": 0.6997629808986944, "NOT": 0.2724902674348483, "NOVOSEVEN": 1.1790354485322518, "NPLATE": 3.814291566420444, "NUCALA": 0.1864790778036579, "OCRELIZUMAB": 0.8499562323426368, "OCTREOTIDE": 2.7555047985676877, "OFEV": 2.2470087561358683, "OLANZAPINE": 0.2091644008891883, "OMALIZUMAB": 0.4054706181495798, "OPDIVO": 0.1895450700907935, "OPSUMIT": 1.6257867504647574, "OZEMPIC": 2.590917654889746, "PACLITAXEL": 0.3710603574534162, "PANTOPRAZOLE": 0.2125682879067088, "PAZOPANIB": 0.808190537532268, "PEGASYS": 1.852503923075951, "PEGINTERFERON": 0.6667401447528872, "PEGINTRON": 0.9716521094561692, "PEMBROLIZUMAB": 0.1534704936125913, "PEMETREXED": 0.6180302887294041, "PLAVIX": 10.479617276839436, "PRADAXA": 3.754822060273004, "PRASUGREL": 12.837270121920746, "RAPAMUNE": 0.3842342607899771, "RELVAR": 0.8097154064243436, "REVATIO": 2.7122332664314617, "REVLIMID": 0.9294875974220004, "RINVOQ": 0.6313384339915926, "RIVAROXABAN": 3.2631607818272244, "ROACTEMRA": 0.5173553231093871, "RUXOLITINIB": 0.9116940835714724, "SHINGRIX": 0.0618906367588265, "SILDENAFIL": 1.84221695870894, "SIMPONI": 0.3927796231638156, "SOLIRIS": 0.534002426958001, "SOVALDI": 0.3491141204403988, "SPIKEVAX": 0.5699692384741483, "SPRYCEL": 0.4003503645787434, "STELARA": 0.3876574387139435, "STIVARGA": 1.2616101297809403, "SUNITINIB": 2.618178916718264, "SUTENT": 3.75529879419692, "TAGRISSO": 0.8564398105352456, "TAMIFLU": 1.197956152290092, "TASIGNA": 0.2724568773937919, "TEMODAL": 0.4892546462942027, "TICAGRELOR": 6.616247987252902, "TOCILIZUMAB": 0.6530289569104032, "TOPOTECAN": 1.477291067304778, "TORISEL": 1.5310893045186, "TOZINAMERAN": 0.6751663770984814, "TRACLEER": 1.0134013169070042, "TRELEGY": 0.3734703332906843, "TRODELVY": 0.5669613774431567, "TRULICITY": 0.1179811988632487, "TWINRIX": 0.6415833793996789, "VAXZEVRIA": 1.3149989032302034, "VECTIBIX": 0.6876602913851918, "VFEND": 0.2742386484190217, "VIAGRA": 0.4803582775979577, "VOTRIENT": 1.8743150082504705, "XARELTO": 10.310139729868803, "XELJANZ": 0.4402005636149445, "XELODA": 0.5897967981169238, "XOLAIR": 0.3696608394647604, "XTANDI": 0.797949593140905, "ZONISAMIDE": 1.6314336130282996, "ZOSTAVAX": 0.14164768788429, "ZYLLT": 15.19584620684367, "ZYPREXA": 0.2624100126698485, "null": 1.138587134084028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4283.json
index d30e8d66490..fd0151db097 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4283.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4283.json
@@ -1 +1 @@
-{"FIASP": 353.48249504892163, "HUMALOG": 14.366962285987526, "NOVORAPID": 122.6253279074092}
\ No newline at end of file
+{"PEMBROLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4284.json
index c6fea6e1f5c..2cb6b93b313 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4284.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4284.json
@@ -1 +1 @@
-{"COMIRNATY": 1.923175377201544}
\ No newline at end of file
+{"ABATACEPT": 4.781006377427552, "ALEMTUZUMAB": 133.55736150482883, "BUDESONIDE": 13.843757216251833, "BUSULFAN": 153.55440210578377, "CELLCEPT": 8.152487995773798, "CICLOSPORIN": 32.282583479408245, "SOLIRIS": 10.645571121736992, "null": 0.1410953558895097}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4285.json
index f9460673b3f..a4192c1c25a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4285.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4285.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 3.2210497797976574, "BRILIQUE": 4.817069845158555, "BRINTELLIX": 3.0410156606306, "CIMZIA": 1.2438520248953178, "CLOPIDOGREL": 3.346996636336995, "COVID19": 1.105287114418553, "DEXAMETHASONE": 1.8486857632947256, "ELIQUIS": 3.824710492078796, "ENBREL": 2.703611448780231, "GARDASIL": 3.3752282841523056, "HUMIRA": 1.6804429649152568, "IBRANCE": 1.1794248072186015, "JANUVIA": 2.21863202571045, "NPLATE": 7.163117585870479, "PEGASYS": 1.8949000997205216, "PLAVIX": 6.002860946020523, "SUTENT": 1.7517292162823972, "VAXZEVRIA": 1.4179847578250853, "VOTRIENT": 1.7339383466652607, "XARELTO": 9.307048360865997, "XELJANZ": 2.4482946489636968, "ZOSTAVAX": 2.847784878443267}
\ No newline at end of file
+{"CELLCEPT": 18.91622928099993, "CICLOSPORIN": 20.437894397329867, "COMIRNATY": 0.580593431997226, "null": 0.6227248239912501}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4286.json
index bf0a52ea45e..fe7002d7837 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4286.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4286.json
@@ -1 +1 @@
-{"CYMBALTA": 2.0972793967484766, "IBRANCE": 1.813438895773432, "NUCALA": 5.665344135254439, "OMALIZUMAB": 4.437324169530553, "XOLAIR": 2.716521190795712, "null": 1.42625154349659}
\ No newline at end of file
+{"ALEMTUZUMAB": 58.524411615350914, "CELLCEPT": 43.14423315038464, "CICLOSPORIN": 27.03553402327932, "null": 0.1595844066623142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4287.json
index 8ade1ec4849..cc6bb7a94c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4287.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4287.json
@@ -1 +1 @@
-{"null": 1.884299257281752}
\ No newline at end of file
+{"ALEMTUZUMAB": 28.893599278375344, "BUSULFAN": 22.53383631011592, "CELLCEPT": 33.41522250690387, "CICLOSPORIN": 74.74041478708031, "METHOTREXATE": 9.557289576750131, "null": 0.5905695262180188}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4288.json
index a44c679e308..e9ec4d1b4be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4288.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4288.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3876383871531897, "COVID19": 1.3475080037812233, "NUCALA": 6.840253189711001, "TOZINAMERAN": 1.7080362252060732}
\ No newline at end of file
+{"ALEMTUZUMAB": 40.17073396879107, "AZATHIOPRINE": 15.579888527703249, "BASILIXIMAB": 35.947028146079234, "BUDESONIDE": 1.4132059744019467, "BUSILVEX": 98.65928912553773, "BUSULFAN": 47.87474573620192, "CAELYX": 8.937936264537738, "CELLCEPT": 24.385689400100848, "CICLOSPORIN": 63.17475050403071, "COMIRNATY": 0.4170889470365577, "CYMBALTA": 1.048232342652352, "CYTARABINE": 3.4555301212070413, "DEXAMETHASONE": 2.243267525166845, "ENTYVIO": 3.100352511224516, "GARDASIL": 3.587175413086636, "HUMAN": 4.607077610382689, "JAKAVI": 7.062068764725214, "METHOTREXATE": 2.348245696559962, "MYCOPHENOLATE": 26.37805706020179, "RITUXIMAB": 4.088679090293736, "SIMPONI": 1.2464381020536774, "SPIKEVAX": 0.2437639120775802, "STELARA": 1.4297093479834546, "TACROLIMUS": 14.84013748743892, "TOZINAMERAN": 0.1453381928088573, "VAXZEVRIA": 0.0731843524609403, "null": 0.3719359343208659}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4289.json
index b13ae708815..5877f4f7af7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4289.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4289.json
@@ -1 +1 @@
-{"BRINTELLIX": 14.373453475273353, "CHAMPIX": 8.391871354704096, "null": 2.8392493690905973}
\ No newline at end of file
+{"ADALIMUMAB": 1.097917877781888, "ALEMTUZUMAB": 46.18966625654815, "AZACITIDINE": 21.448494226992747, "BUDESONIDE": 2.525381270144168, "BUSILVEX": 168.89007609724024, "BUSULFAN": 99.66345285797344, "CARMUSTINE": 30.197945431269453, "CELLCEPT": 5.881188237930019, "CICLOSPORIN": 21.523232153836297, "COMIRNATY": 1.317132632449903, "DOXORUBICIN": 24.616525964638715, "JAKAVI": 4.17864784685497, "METHOTREXATE": 6.479404851299044, "MYCOPHENOLATE": 19.043328315297224, "RUXOLITINIB": 36.77429039852652, "SPIKEVAX": 0.623852588162573, "VAXZEVRIA": 0.1162316784316059, "null": 0.2609822357972563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/429.json
index c2f1ddc354d..029624c4444 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/429.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/429.json
@@ -1 +1 @@
-{"CYMBALTA": 5.19229069199196, "EYLEA": 5.0115993190249695, "TAMIFLU": 2.790985482849434, "TOVIAZ": 5.705853653412107, "ZYPREXA": 2.476663455096601, "null": 7.209278183284273}
\ No newline at end of file
+{"null": 0.968520450522806}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4290.json
index 79d92a4fc76..b84ca33253e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4290.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4290.json
@@ -1 +1 @@
-{"null": 1.3193243928001126}
\ No newline at end of file
+{"CELLCEPT": 56.40970901851848, "CICLOSPORIN": 15.917854075513011, "null": 0.4011177016724823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4291.json
index b6584e97c8c..f77705136a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4291.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4291.json
@@ -1 +1 @@
-{"MISOPROSTOL": 44.36925233704665, "null": 298.2484284628898}
\ No newline at end of file
+{"ESOMEPRAZOLE": 3598.596093268954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4292.json
index 1ad0469688b..e3c19325d35 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4292.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4292.json
@@ -1 +1 @@
-{"null": 3.442779540174401}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4293.json
index c69ca003cf7..06376024a03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4293.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4293.json
@@ -1 +1 @@
-{"KEPPRA": 10.985256136668514, "null": 1.309944743076621}
\ No newline at end of file
+{"CIALIS": 10.493819189325457, "IBUPROFEN": 2.037564499430488, "SILDENAFIL": 13.844145622627291, "VAXZEVRIA": 0.028006671870707, "VIAGRA": 5881.196160640347, "null": 0.0748062174797485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4294.json
index 3c2f63f9083..86fd4c83f17 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4294.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4294.json
@@ -1 +1 @@
-{"APIDRA": 2.9074057633998875, "COMIRNATY": 1.2110461038152247, "FASLODEX": 5.237852693408737, "FENTANYL": 1.5860222468414114, "GARDASIL": 3.849267172718184, "INSULIN": 2.0574446513412665, "MENVEO": 23.65567321618604, "NIMENRIX": 4.377577023650129, "OPTIMARK": 8.037262269118271, "SHINGRIX": 6.626357417620879, "SPIKEVAX": 1.4149685019356957, "TOZINAMERAN": 7.257153569451437, "VAXZEVRIA": 1.8038468806324224}
\ No newline at end of file
+{"ATAZANAVIR": 132.4653258454617, "KALETRA": 43.67801909105801, "LOPINAVIR": 982.4939344662204, "RITONAVIR": 787.4455344018598, "null": 1.096314576571828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4295.json
index 73a31d9deec..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4295.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4295.json
@@ -1 +1 @@
-{"NIMENRIX": 195.46272851523128, "TOZINAMERAN": 3.148713819821033}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4296.json
index 2e591ab413e..b1354742e6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4296.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4296.json
@@ -1 +1 @@
-{"FENTANYL": 6.199417624623381, "INFANRIX": 66.37719253618003, "KEPPRA": 3.973170445646228, "MIDAZOLAM": 31.11785217764841, "ZYPREXA": 3.038217069702191, "null": 3.448681650578457}
\ No newline at end of file
+{"BRILIQUE": 17.514215555376964, "INSULIN": 12.210207537630676, "PLAVIX": 14.011890286933756, "null": 2.5665952946666475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4297.json
index e0e26d41a83..e9833ca3015 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4297.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4297.json
@@ -1 +1 @@
-{"MMRVAXPRO": 73.2441974743109}
\ No newline at end of file
+{"APREPITANT": 194.66640392393444, "CLOPIDOGREL": 3.2758967292649244, "COSENTYX": 2.9477459223378157, "PLAVIX": 4.323415021738636, "null": 2.215571528879201}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4298.json
index 0251f1e25fd..0e0d15e2bd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4298.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4298.json
@@ -1 +1 @@
-{"ROTATEQ": 140.07736793415765, "SUBOXONE": 175.21427846357096}
\ No newline at end of file
+{"AFINITOR": 0.5591211674785237, "AIMOVIG": 0.573536743002972, "APREPITANT": 14.993387411042413, "BOSULIF": 3.980380618077744, "BRINTELLIX": 1.9043972166205407, "BYDUREON": 7.305736548959318, "BYETTA": 4.1031336814865575, "CHAMPIX": 1.3520953580538038, "CLOPIDOGREL": 2.89149082852881, "COMIRNATY": 0.4194365267440791, "CYMBALTA": 0.4848171428252525, "DEXAMETHASONE": 0.6083551993760958, "DULAGLUTIDE": 14.119817142015128, "ELIQUIS": 0.7493372661140026, "ESBRIET": 3.8678115856977193, "FASLODEX": 1.0746262779773763, "FORSTEO": 1.9503170125317857, "FULVESTRANT": 3.4263555031303867, "GARDASIL": 0.3845033792650648, "HUMALOG": 0.3594831967979669, "IBRANCE": 1.560876637190649, "JANUMET": 0.813361228667511, "JARDIANCE": 0.5262502894248334, "KEPPRA": 0.4915718957472362, "LANTUS": 0.8172288110394388, "OFEV": 1.8656600175241729, "OXYBUTYNIN": 8.387980509593854, "OZEMPIC": 13.080785637197332, "PEGASYS": 0.8235125231536482, "PLAVIX": 0.5286746723091119, "RYBELSUS": 36.37387142073739, "SAXENDA": 46.19149517450522, "SPIKEVAX": 0.3377653337263706, "SUTENT": 2.502658975755995, "TEDUGLUTIDE": 49.58185978617529, "TOVIAZ": 3.4894684076972378, "TOZINAMERAN": 0.6743936227706495, "TRULICITY": 64.50965298380565, "VAXZEVRIA": 0.3941012829529225, "VICTOZA": 19.834009462607053, "XELJANZ": 0.5192911223044727, "XTANDI": 0.7344327280443191, "null": 1.2039542274365658}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4299.json
index a876a8ee7e8..dd15c3f8f4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4299.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4299.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 86.67039268480089, "SUBOXONE": 68.77461683192561, "null": 1.9375522878849023}
\ No newline at end of file
+{"ALIMTA": 9.190805937962253, "APROVEL": 6.778911350005282, "ARAVA": 0.209450051708246, "AZATHIOPRINE": 4.114270808264075, "BETAFERON": 5.753397019313024, "CELLCEPT": 1.130107406973707, "CIMZIA": 1.2518304878034956, "CLOPIDOGREL": 0.9479395337564048, "COMIRNATY": 1.1246045939642506, "COSENTYX": 5.6059588239965725, "ELIQUIS": 0.9573019161727394, "ENTRESTO": 2.421818471548661, "FASLODEX": 1.7356607291791484, "FORSTEO": 1.6644517736775395, "HUMALOG": 0.7199692718146473, "HUMIRA": 1.484520702920777, "INCIVO": 3.220784653708336, "JAKAVI": 3.1119792930730514, "LANTUS": 1.0903429772688258, "METHOTREXATE": 2.935325958795919, "PEGASYS": 1.081034333155739, "PEGINTERFERON": 2.00152995649778, "PEMETREXED": 8.459825764561852, "RINVOQ": 4.251572581841722, "ROACTEMRA": 20.862966894416907, "SHINGRIX": 2.023785332942559, "SIMPONI": 5.106090008113961, "SOLIRIS": 1.6478393605076789, "SPIKEVAX": 1.916152004067709, "STELARA": 6.165448266574892, "SUTENT": 0.9409135728436088, "TRACLEER": 2.0635038695183754, "VAXZEVRIA": 0.4330875762025342, "XELJANZ": 0.8391815138314851, "null": 0.4825849455666474}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/43.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/43.json
index 01cc05757a5..a92b6c74199 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/43.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/43.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3320772180869276}
\ No newline at end of file
+{"AFINITOR": 0.9255907851091724, "ARAVA": 0.9721983297291208, "ASPARAGINASE": 5.133888882265375, "BYETTA": 2.6399743846188577, "CICLOSPORIN": 3.190673429927936, "CLOPIDOGREL": 5.135010314676991, "COMIRNATY": 0.1992088655438265, "CYTARABINE": 3.6750197177021184, "ENOXAPARIN": 13.60593704558574, "ENTYVIO": 1.8653373279924532, "EXJADE": 4.693681446594666, "GARDASIL": 1.5097614394861818, "HUMIRA": 1.3436190048396772, "IBUPROFEN": 3.410877309239667, "JANUVIA": 1.6999797630505706, "KALETRA": 2.464720455677494, "LEVOFLOXACIN": 1.0663836988362885, "METHOTREXATE": 1.1940158758299269, "NEXAVAR": 0.7651076267611657, "OLANZAPINE": 1.4701187643740712, "PEGINTERFERON": 2.05175768503502, "ROTATEQ": 8.782813809642887, "SPIKEVAX": 0.2117951747115443, "STIVARGA": 1.5933160748579882, "SUTENT": 0.5321074491274912, "TASIGNA": 2.386278148493243, "TOZINAMERAN": 0.4462843168522753, "VAXZEVRIA": 0.1766802829536158, "XELJANZ": 0.7175745193735649, "ZOSTAVAX": 1.846825495976646, "null": 2.067225979275489}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/430.json
index 81b002c3278..cd6a488d6b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/430.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/430.json
@@ -1 +1 @@
-{"IBUPROFEN": 8.013172984045115, "PEGASYS": 6.427978045524723, "SUTENT": 4.024162274141954}
\ No newline at end of file
+{"null": 1.0160645214141928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4300.json
index 925984eb1a5..6b836bbcea7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4300.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4300.json
@@ -1 +1 @@
-{"null": 1.0379271266124754}
\ No newline at end of file
+{"PEGINTERFERON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4301.json
index 46163309d49..9a7be3ce04b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4301.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4301.json
@@ -1 +1 @@
-{"EVEROLIMUS": 117.93038841103424, "KEPPRA": 7.414556321326129, "LEVETIRACETAM": 45.33390919673814, "ROTATEQ": 20.20028806648838, "SYNAGIS": 30.43452000910176, "VIGABATRIN": 355.6710013672589, "null": 2.8970580602378413}
\ No newline at end of file
+{"ABACAVIR": 3.14560439492838, "ABASAGLAR": 1.1144661046902684, "ABATACEPT": 0.2310028513109049, "ABILIFY": 0.1175986421360838, "ACTOS": 0.3882351492186371, "ACTRAPID": 0.8472108487950036, "ADALIMUMAB": 0.7430121575765903, "ADCETRIS": 0.5010919124029303, "ADCIRCA": 0.4675312531365133, "ADEMPAS": 0.3075820447497032, "ADENURIC": 1.8355670339742565, "AERIUS": 1.6454751701163126, "AFINITOR": 0.7196450425575026, "AIMOVIG": 0.6586224837335259, "AKYNZEO": 4.181718560292917, "ALDARA": 3.508653657525994, "ALEMTUZUMAB": 0.3869408054995095, "ALIGN": 6.74560542679206, "ALIMTA": 1.401821378531727, "ALOXI": 1.191844380947756, "AMELUZ": 3.1465171512188377, "AMIKACIN": 0.2465647697154722, "AMINOSALICYLIC": 3.328645003586926, "ANAKINRA": 0.0885477807849778, "ANORO": 0.1807616125681859, "APIDRA": 0.493687305468492, "APIXABAN": 0.2177826548485786, "APREMILAST": 0.7926642591149278, "APROVEL": 0.5498989387666963, "APTIVUS": 2.7625540431608644, "ARANESP": 0.243019902918242, "ARAVA": 0.3925208108756343, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4302.json
index 23003a6b496..e0f23e02d9b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4302.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4302.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 27.81106275828233, "ROTATEQ": 769.410623990887}
\ No newline at end of file
+{"COMIRNATY": 0.3033200398639974, "SPIKEVAX": 0.6790153182367304, "null": 1.401419671041668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4303.json
index 0bb34ac3f39..b44504616ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4303.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4303.json
@@ -1 +1 @@
-{"BEXSERO": 297.95322778250386, "NIMENRIX": 69.99738985663316, "PREVENAR": 192.17734624387012, "ROTATEQ": 104.53136654764334, "SUBOXONE": 17.59611855607073, "TOZINAMERAN": 2.188421430891237}
\ No newline at end of file
+{"null": 0.9840497355079452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4304.json
index 5e28b9d1f1c..d92e8cef423 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4304.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4304.json
@@ -1 +1 @@
-{"ABILIFY": 6.195724303536501, "APIDRA": 2.5236176431260184, "BRILIQUE": 6.463185841828418, "CHAMPIX": 3.2579505493089065, "CLOPIDOGREL": 1.6808535761427592, "DAPAGLIFLOZIN": 14.08792876526469, "ELIQUIS": 4.044953239724482, "ENTRESTO": 2.5990211841000885, "EXFORGE": 22.452804960152772, "FORSTEO": 2.76975931127729, "FORXIGA": 2.330326848833378, "HUMALOG": 2.0355116500414003, "JANUMET": 1.865058749166838, "JANUVIA": 1.5129454393217563, "JARDIANCE": 1.3353209368920866, "LANTUS": 4.6052191510502185, "MICARDIS": 5.090403872455663, "RASILEZ": 7.0628793897563735, "SIMPONI": 1.915613474653795, "STELARA": 1.866745173748808, "SUTENT": 1.5852631294783657, "TASIGNA": 5.2910010868976745, "VALSARTAN": 9.34408773644059, "VIAGRA": 5.120376813198256, "VOTRIENT": 1.239375124034452, "XELJANZ": 1.065219802115996, "null": 1.577835328159906}
\ No newline at end of file
+{"null": 1.655389132201088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4305.json
index 23590c6cbc1..da367ca8da1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4305.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4305.json
@@ -1 +1 @@
-{"XELJANZ": 9.528866665780384}
\ No newline at end of file
+{"COMIRNATY": 0.7384400662348386, "SPIKEVAX": 1.9990878568262525, "null": 0.2381016593947709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4306.json
index ff742434df7..a5a8fe7445d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4306.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4306.json
@@ -1 +1 @@
-{"PEGASYS": 5.59189523804532}
\ No newline at end of file
+{"AFINITOR": 0.3695986271335116, "ALDARA": 13.707163544445548, "ALIMTA": 1.4701544339361798, "ARAVA": 0.1392391097822941, "BONVIVA": 1.7160044897221662, "BOSULIF": 2.351200422610988, "BRAFTOVI": 0.8186423994566991, "CABOMETYX": 0.9771848510585952, "CELECOXIB": 1.727307515626335, "CELLCEPT": 0.4241110934610036, "CHAMPIX": 1.2948706869886364, "CICATRIZANTS": 133.40075345068618, "CICLOSPORIN": 0.1414921345002043, "CIMZIA": 0.3037415480946157, "CLOPIDOGREL": 0.6766612464650816, "COMBIVIR": 1.5378120340965038, "COMIRNATY": 0.3275833492137001, "COSENTYX": 0.2165431804452337, "COTELLIC": 3.710378415420109, "CYMBALTA": 0.2702135578859151, "DABIGATRAN": 22.86023197250304, "DEXAMETHASONE": 0.6092292786930448, "DOCETAXEL": 0.4575885942894783, "ELIQUIS": 0.1145816565770946, "ERLEADA": 8.62791842080411, "EVENITY": 1.4245235763912305, "EXFORGE": 0.6195286134973527, "EXJADE": 0.752621822769273, "FASLODEX": 0.472605166225481, "FORXIGA": 0.407590643267274, "GARDASIL": 0.5771124911197029, "HARVONI": 0.7034470829458741, "HUMALOG": 0.1751293643626691, "IBUPROFEN": 2.542645888303666, "IMIQUIMOD": 25.1010419806324, "INCIVO": 3.1874541747312883, "INSULIN": 0.4474462841691487, "IPILIMUMAB": 0.8368665732971452, "IRESSA": 1.149832335993702, "KALETRA": 1.240492409879386, "KEPPRA": 0.6875750457279451, "KEYTRUDA": 4.452435183333456, "LANTUS": 0.2506483584225683, "LENVIMA": 1.5426160908897142, "LEVETIRACETAM": 0.7021184557313532, "LEVOFLOXACIN": 2.6130436160115504, "LYRICA": 1.6415519146220667, "MEKINIST": 1.652068761612547, "MICARDIS": 2.914028653213728, "MMRVAXPRO": 0.8525106092530493, "MODERNA": 0.7804516980581879, "NEXAVAR": 19.887232018501354, "NIMENRIX": 1.6863123878260022, "NOT": 1.9810446882172168, "OLYSIO": 1.4069407070513924, "OPDIVO": 7.386131501351977, "OSELTAMIVIR": 6.166523403500603, "PEGASYS": 1.761176335971415, "PEGINTERFERON": 3.9199138697663782, "PEGINTRON": 3.441690826109807, "PEMBROLIZUMAB": 0.943603031914168, "PLAVIX": 2.104785816598572, "PREVENAR": 3.518161129250095, "PROTELOS": 7.267953419498085, "RINVOQ": 0.8232737502040806, "ROACTEMRA": 0.5242660548082777, "ROTATEQ": 0.6939264490893469, "SHINGRIX": 0.5553503322004152, "SIMPONI": 0.2687148153356513, "SORAFENIB": 5.510979238909851, "SOVALDI": 1.2297768325455802, "SPIKEVAX": 0.3169036917632635, "STELARA": 0.5022421434401668, "STIVARGA": 13.90676315287218, "SUTENT": 0.2280416429924119, "TAGRISSO": 5.641609336630526, "TAMIFLU": 8.721989369917017, "TEMODAL": 2.18331725783742, "TOVIAZ": 0.7519891238334656, "TOZINAMERAN": 0.3340803370274526, "TWINRIX": 1.2036033048740449, "VAXZEVRIA": 0.1198477766498737, "VFEND": 1.0345537836270382, "VIMPAT": 0.9028018098136156, "VIRAMUNE": 3.425540464276031, "XTANDI": 0.2278606947828405, "ZYCLARA": 9.560866635513914, "ZYPREXA": 0.320933524174089, "null": 2.47978150134553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4307.json
index e0847f5f99d..e6db6f8ffd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4307.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4307.json
@@ -1 +1 @@
-{"ARAVA": 1.2908145729881435, "CICLOSPORIN": 3.918392019208175, "LANTUS": 3.272265569619563, "PEGASYS": 2.1984251621212323, "SIMPONI": 11.389845601479012, "XELJANZ": 8.246921635446991}
\ No newline at end of file
+{"AFINITOR": 1.1489136165906086, "ARAVA": 0.1956132738033638, "BOSUTINIB": 36.57081019828801, "CIMZIA": 1.3323152900458215, "COMIRNATY": 1.018085352257424, "COSENTYX": 3.3765152722582803, "COTELLIC": 19.465977813204223, "DABRAFENIB": 15.347927069937317, "ENTYVIO": 11.642407641011555, "GARDASIL": 3.046760942743399, "GLYCOPYRRONIUM": 22.3821710176236, "KALETRA": 3.424424196127956, "KEYTRUDA": 0.5924074906861622, "LEVOFLOXACIN": 2.13498120692078, "LYNPARZA": 4.23001175676799, "MEKINIST": 21.60531072498026, "MODERNA": 2.103756079704656, "PANTOPRAZOLE": 11.061684725114096, "PEGASYS": 2.434671991097386, "PEGINTRON": 1.864940741461268, "RINVOQ": 3.2443334935014256, "SIMPONI": 1.1336841536976268, "SPIKEVAX": 0.9940559934804952, "STELARA": 2.8870596395405888, "TAMIFLU": 2.1780017781447123, "TOZINAMERAN": 0.5757505772447101, "VAXZEVRIA": 0.4307606998853115, "XOLAIR": 1.022939046103619, "null": 0.7779894526733035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4308.json
index b64b9e10c1d..a88d741a21e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4308.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4308.json
@@ -1 +1 @@
-{"ABACAVIR": 8.592568638456447, "ABATACEPT": 5.802664379808832, "ABRAXANE": 1.179070770153816, "ACETAMINOPHEN": 12.566858614856026, "ACLIDINIUM": 1.4781353573796736, "ADALIMUMAB": 3.650537269877672, "ADCETRIS": 1.753449830363653, "ADVAGRAF": 1.741898770416339, "AFINITOR": 1.0896143685872235, "ALEMTUZUMAB": 3.1969882535044176, "ALIMTA": 1.615356327733752, "AMIKACIN": 1.45930346072292, "ANAKINRA": 3.525540576911925, "ANTIBIOTICS": 1.485151249425977, "APREPITANT": 12.10962647505432, "ARANESP": 1.1563430909384926, "ARAVA": 4.30173791377368, "ARZERRA": 2.7860159443706847, "ASPARAGINASE": 1.8440193664239863, "AUBAGIO": 1.140173734265357, "AVASTIN": 1.2777837749762042, "AZACITIDINE": 5.6438588113847, "AZATHIOPRINE": 1.129377755163072, "AZTREONAM": 3.182001480149856, "BASILIXIMAB": 1.6493313040632565, "BELIMUMAB": 1.0802398786609546, "BENLYSTA": 3.122456101302248, "BENRALIZUMAB": 2.248190955785128, "BETAFERON": 1.2396015531388649, "BLINCYTO": 3.0408832221837487, "BOCEPREVIR": 1.7424254121090357, "BORTEZOMIB": 3.4626762145622023, "BOSULIF": 1.071794082983933, "BRAFTOVI": 1.3686806471999589, "BUSILVEX": 2.909542338639981, "BUSULFAN": 3.872066821518728, "CAELYX": 1.5511287640049296, "CANCIDAS": 1.1501290464569711, "CARFILZOMIB": 2.570526223708381, "CARMUSTINE": 3.252099430036429, "CASPOFUNGIN": 2.241306870191206, "CELECOXIB": 1.5413931518541424, "CELLCEPT": 2.4627052796915785, "CERTOLIZUMAB": 4.241586066944304, "CHLORHEXIDINE": 18.513057886489943, "CICLOSPORIN": 2.4107438407024526, "CIMZIA": 8.48455375233668, "CLADRIBINE": 2.479593854866181, "CLOFARABINE": 3.0705472904990945, "COBIMETINIB": 1.890437644816898, "COSENTYX": 2.8675140210450927, "CRESEMBA": 2.545807893418941, "CUBICIN": 2.5585112358098008, "CYTARABINE": 4.226800370417621, "DAPTOMYCIN": 2.912448600450679, "DARATUMUMAB": 1.8385171824601485, "DARZALEX": 3.3786757462722328, "DECITABINE": 4.098102477356623, "DEFITELIO": 2.733157101792721, "DEXAMETHASONE": 2.8162433887863134, "DOCETAXEL": 1.2823325680401163, "DOXORUBICIN": 3.125625815851294, "DUAKLIR": 10.829053799311415, "DUPILUMAB": 3.591200522643096, "DUPIXENT": 2.070912006595261, "ENBREL": 3.261610439706248, "ERELZI": 4.588255692300145, "ESBRIET": 1.4807710988691911, "EVOLTRA": 7.635305913920701, "EXJADE": 3.6702916949729456, "FASENRA": 1.586199438893534, "FENTANYL": 1.1039297378068726, "FILGRASTIM": 4.540561875374493, "GAZYVARO": 2.8107207937120644, "GLYCOPYRRONIUM": 6.229394483446552, "GOLIMUMAB": 5.081654607398911, "HALAVEN": 1.0051601710036382, "HEMLIBRA": 1.6895641458890285, "HIZENTRA": 4.452126040231827, "HUMALOG": 1.003995318429009, "HUMIRA": 2.634797379235464, "HYQVIA": 3.4340667064465413, "IBRANCE": 2.1970828220862284, "IBRUTINIB": 5.288100759325498, "ICLUSIG": 2.499938531406007, "IMATINIB": 1.1590028391118925, "IMBRUVICA": 1.4190670753595551, "IMNOVID": 3.7309862787241928, "INFLIXIMAB": 1.6098958894976425, "INTERFERON": 1.2574188046893529, "IRON": 1.6646762539400906, "JAKAVI": 3.688428738706252, "JARDIANCE": 1.3137452639170786, "JEVTANA": 1.9203172968903508, "KAFTRIO": 3.036488738290396, "KALYDECO": 9.354718643969102, "KESIMPTA": 3.3217266954155638, "KYMRIAH": 1.5057434088415134, "KYPROLIS": 3.6894298200637, "LEFLUNOMIDE": 1.9855471224877064, "LEMTRADA": 1.4461002103283562, "LENALIDOMIDE": 3.173961515205887, "MABCAMPATH": 2.892377519863435, "MABTHERA": 3.3525329448264727, "MAVENCLAD": 1.4532157527609642, "MEKINIST": 1.3510036398038936, "MEPOLIZUMAB": 3.690326293272443, "MERCAPTOPURINE": 1.2859122769931506, "METHOTREXATE": 2.366666544110412, "MICAFUNGIN": 2.8467628129589446, "MIRCERA": 1.2684220171156289, "MYCOPHENOLATE": 2.3863514447589824, "NAGLAZYME": 2.4980511055612875, "NEULASTA": 2.1977624183193063, "NINLARO": 1.3045001166047916, "NOXAFIL": 2.389487812297622, "NPLATE": 1.425692397517076, "NUCALA": 2.156178613533952, "OBINUTUZUMAB": 2.104484747780238, "OFEV": 1.1914484776488743, "OLYSIO": 1.1820469933434423, "OPSUMIT": 1.4777108268398245, "ORKAMBI": 13.5450673932968, "PEGASPARGASE": 3.015463228536685, "PEGFILGRASTIM": 4.571167718882419, "PEMETREXED": 1.5902719334748767, "POMALIDOMIDE": 4.520905249254847, "PRIVIGEN": 1.4822855061616875, "RAPAMUNE": 3.43904112994251, "REMICADE": 1.353695707235069, "REMSIMA": 3.401989397300177, "REVATIO": 1.668149079651822, "REVLIMID": 2.265025484568219, "RINVOQ": 2.3340980809170984, "RITUXIMAB": 3.559668631478021, "ROACTEMRA": 4.613048949273127, "RUBRACA": 1.007999575369595, "RUCONEST": 2.3199258258702296, "RUXOLITINIB": 1.9046711717928275, "RYDAPT": 3.195243809750964, "SEEBRI": 5.994181775268377, "SIMPONI": 8.20750251453754, "SKYRIZI": 2.076296230291741, "SOLIRIS": 4.402589324630535, "SPINRAZA": 3.2193352830439386, "SPRYCEL": 1.8567005587159864, "STELARA": 1.9840854401155783, "SUTENT": 1.0708751138776471, "SYNAGIS": 2.5192498127748544, "TASIGNA": 1.0772326504617216, "TEMODAL": 1.518053278176462, "TEMOZOLOMIDE": 2.4208713724480457, "THALIDOMIDE": 2.6350909874578123, "THIOTEPA": 1.6364835466472047, "TOBI": 4.371839808250974, "TOBRAMYCIN": 2.1847065729397137, "TOCILIZUMAB": 1.5679048045473891, "TOPOTECAN": 1.5758411968046455, "TRACLEER": 1.6105646749381948, "TREMFYA": 2.3025082836873763, "TRODELVY": 1.5718571944654625, "VECTIBIX": 1.4412726675667369, "VELTASSA": 2.09302967727532, "VENCLYXTO": 6.002955843660029, "VENETOCLAX": 8.29623509573242, "VFEND": 1.736881879318284, "VOTRIENT": 1.2628615697161896, "VYXEOS": 3.754817677984384, "XELJANZ": 5.05538045120217, "XOFIGO": 1.0476852299428838, "XOLAIR": 1.1579977408032864, "XTANDI": 1.0156201717435809, "YESCARTA": 2.92690775161163, "ZOMETA": 1.184520018113634}
\ No newline at end of file
+{"COMIRNATY": 0.9132322233480252, "LEVOFLOXACIN": 2.3698189757266084, "MMRVAXPRO": 2.844969311147835, "SHINGRIX": 2.310663327175245, "SPIKEVAX": 0.6080507873234814, "TOZINAMERAN": 0.7616613903663739, "VAXZEVRIA": 0.2231353803281897, "null": 2.1434858377484622}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4309.json
index be2caef04f9..8f3be57e2a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4309.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4309.json
@@ -1 +1 @@
-{"CELLCEPT": 54.31946965833135, "CYTARABINE": 57.770230171665865}
\ No newline at end of file
+{"JEVTANA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/431.json
index c83df63a20e..bb3148b2706 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/431.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/431.json
@@ -1 +1 @@
-{"AGOMELATINE": 8.890327335125598, "ATRIPLA": 62.04720501322591, "CONTRAST": 3.1655396872128843, "KALETRA": 1.6529356182025776, "OPTIMARK": 15.623318961576356, "STRIBILD": 37.93305612535252, "TRUVADA": 36.234057817902766, "VIREAD": 20.621645383123106}
\ No newline at end of file
+{"CLOPIDOGREL": 14.710967828403213, "COMIRNATY": 0.5899664640245029, "SPIKEVAX": 0.4120228362236298, "VAXZEVRIA": 0.3236885569063042, "null": 0.8347622849396195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4310.json
index e5fd56233b7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4310.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4310.json
@@ -1 +1 @@
-{"CELLCEPT": 20.291127400644083, "XOLAIR": 14.404427049283964}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4311.json
index c7c706bbca0..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4311.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4311.json
@@ -1 +1 @@
-{"AXICABTAGENE": 230.9584636332921, "BORTEZOMIB": 35.04204649299487, "BUSULFAN": 55.12921392895281, "CICLOSPORIN": 11.158362676158124, "MYCOPHENOLATE": 50.180485758671146, "PEGINTRON": 14.047558024561583, "SOVALDI": 75.01193638089899}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4312.json
index 4a8cab14312..053ac822ae3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4312.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4312.json
@@ -1 +1 @@
-{"ANAKINRA": 6.093063323525795, "COMIRNATY": 3.325213944130507, "COSENTYX": 4.296125625596934, "GARDASIL": 4.791435754704932, "IBRANCE": 1.196328783121052, "INFANRIX": 13.66316826374963, "JORVEZA": 534.7258899892737, "MMRVAXPRO": 2.883652658598969, "SPIKEVAX": 1.3057921271428825, "TWINRIX": 10.598674600215276, "XELJANZ": 1.6023194662022495}
\ No newline at end of file
+{"CICLOSPORIN": 7.878872973734662, "COMIRNATY": 0.1013220656262813, "COSENTYX": 36.55404343376106, "STELARA": 39.17345041399189, "TREMFYA": 25.113494033747774, "null": 1.018505248132595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4313.json
index 6da6e667bec..2c392104490 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4313.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4313.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"COMIRNATY": 0.6985726942095294, "VAXZEVRIA": 0.7345925831021688, "null": 0.7688092158901008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4314.json
index d0efa013ffd..14cfe0b3118 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4314.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4314.json
@@ -1 +1 @@
-{"null": 2.154150020697041}
\ No newline at end of file
+{"null": 2.835034206059269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4315.json
index f19a8a7c689..c6c079d7441 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4315.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4315.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3954379812493451, "COVID19": 1.048236337191108, "CYMBALTA": 1.0870790037219171, "GARDASIL": 21.47945737499857, "SIMPONI": 2.3080218059244104, "TOZINAMERAN": 1.2506204118689606, "XOLAIR": 3.316866878219124}
\ No newline at end of file
+{"ARANESP": 36.45807734757906, "null": 0.7017922362487885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4316.json
index 4f59043d84a..e51e66e9c69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4316.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4316.json
@@ -1 +1 @@
-{"ALIMTA": 9.738364710619626, "CICLOSPORIN": 3.4932304234943587, "KEYTRUDA": 5.131562851067691, "OPDIVO": 7.630901397794385, "ROACTEMRA": 15.447790079377029, "SIMPONI": 7.1526169819697145}
\ No newline at end of file
+{"VFEND": 117.60732539112094, "null": 0.3371386286315536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4317.json
index 827f8056408..ac8b48ce87b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4317.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4317.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1674483270982428}
\ No newline at end of file
+{"COMIRNATY": 0.4884303883514432, "null": 2.054359802321779}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4318.json
index 6f3fa4b9a2d..e14e2119e2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4318.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4318.json
@@ -1 +1 @@
-{"AMBRISENTAN": 479.62612411042807, "APIXABAN": 232.84937188389412, "CLOPIDOGREL": 7.596002163034264, "LYRICA": 26.167542330768477}
\ No newline at end of file
+{"ASPARAGINASE": 25.75877048984337, "CANCIDAS": 110.59922593877658, "COMIRNATY": 0.1100140537703951, "null": 1.8098580781078315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4319.json
index ff8e014b92b..12a94b8b227 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4319.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4319.json
@@ -1 +1 @@
-{"AZTREONAM": 112.58805987505896, "CAYSTON": 212.1742150583465, "KAFTRIO": 108.21878536046133, "KALYDECO": 1090.7775353011405, "LAMIRA": 159.55301259006828, "ORKAMBI": 2780.692803587542}
\ No newline at end of file
+{"BENLYSTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/432.json
index f55b0b64c54..ef80608db89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/432.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/432.json
@@ -1 +1 @@
-{"null": 2.434915845771003}
\ No newline at end of file
+{"METHOTREXATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4320.json
index e45bb874b7a..e0f2df64f9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4320.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4320.json
@@ -1 +1 @@
-{"STELARA": 17.41323762565731}
\ No newline at end of file
+{"ALEMTUZUMAB": 23.26194720803139, "BORTEZOMIB": 22.56597035148707, "CICLOSPORIN": 2.584029076507158, "CYTARABINE": 25.142345185944997, "DEXAMETHASONE": 5.549743119403686, "INCIVO": 22.441856504678576, "SOLIRIS": 7.3440781025868835, "null": 0.4477682028266514}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4321.json
index 9fb43c50a5e..e4755e063d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4321.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4321.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 20.89760281240041, "null": 1.7046058036911742}
\ No newline at end of file
+{"ALEMTUZUMAB": 7.166456510565337, "AMIKACIN": 11.186862530832292, "ARANESP": 1.813309813235349, "ASPARAGINASE": 7.496196773771023, "BASILIXIMAB": 23.617272533172518, "BUSULFAN": 11.521306008617, "CELLCEPT": 6.131465948577728, "CICLOSPORIN": 8.953756848817381, "CIMZIA": 0.7839961663299283, "COMIRNATY": 0.0529508378736678, "CYTARABINE": 14.761084256156671, "DEXAMETHASONE": 3.1092100583490416, "ELIQUIS": 0.5014330791616423, "ENTYVIO": 9.091877979857244, "EXJADE": 5.191075715586276, "HIZENTRA": 5.255138738924435, "HUMALOG": 1.2915374777495383, "IBRANCE": 1.466171527387143, "IBUPROFEN": 4.67761650013148, "JARDIANCE": 5.560816785480192, "LEVOFLOXACIN": 3.3109383656252813, "MEPOLIZUMAB": 2.813342756027833, "MYCOPHENOLATE": 19.504960946915293, "PEGINTERFERON": 5.899741271473969, "SIMPONI": 1.1759475843570828, "SOLIRIS": 3.5523368456675706, "SUBOXONE": 1.7501903821903335, "XELJANZ": 2.937236861029372, "null": 0.7742966541836778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4322.json
index b9e2d70650e..6f67beeb341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4322.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4322.json
@@ -1 +1 @@
-{"ABILIFY": 10.184574056984806, "BUPRENORPHINE": 7.959547325910669, "GARDASIL": 8.486809905560957, "PEGASYS": 2.906384737347863, "STELARA": 3.4362253054291165, "null": 1.353338303321032}
\ No newline at end of file
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4323.json
index cfdb88acdb7..15154854f4f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4323.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4323.json
@@ -1 +1 @@
-{"GARDASIL": 7.587488265601696, "null": 1.1687080327290746}
\ No newline at end of file
+{"AMIKACIN": 31.99014606105109, "ASPARAGINASE": 8.326581465317668, "BUSULFAN": 16.536877853978428, "CICLOSPORIN": 2.946332785291568, "COMIRNATY": 0.0575078931310407, "CYTARABINE": 13.254884277002946, "DEXAMETHASONE": 13.373417124400287, "JAKAVI": 7.085066108730372, "JARDIANCE": 4.672603585281306, "PEGASYS": 2.921100836387362, "PEGINTRON": 2.268377086942889, "SOLIRIS": 9.6912800331151, "null": 0.5300224106227551}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4324.json
index cd9117c0f13..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4324.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4324.json
@@ -1 +1 @@
-{"null": 5.063403774760271}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4325.json
index e69726130d1..f72104745fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4325.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4325.json
@@ -1 +1 @@
-{"ABATACEPT": 6.304272084763363, "ACLASTA": 3.3921359423737103, "ACLIDINIUM": 1.6873382538950712, "ADALIMUMAB": 6.238152895063161, "AFINITOR": 1.3568604651471166, "ALDARA": 7.306664193487716, "AMGEVITA": 22.37178063566425, "AMIKACIN": 1.846740105856826, "ANAKINRA": 1.220331692381758, "APREMILAST": 6.198283395343084, "ARAVA": 1.673844454104494, "ARIXTRA": 2.618577717496235, "AYESURBY": 114.64005417024296, "AZATHIOPRINE": 6.387299244013867, "BASILIXIMAB": 1.7372971508195665, "BELIMUMAB": 7.592577911403811, "BENLYSTA": 3.025540944226234, "BENRALIZUMAB": 3.125464878915571, "BEOVU": 1.0578388345437015, "BONVIVA": 1.3338508226092498, "CELECOXIB": 1.1840156377602555, "CICLOSPORIN": 1.983150157100845, "CIMZIA": 2.285354297074665, "COSENTYX": 3.589610271419706, "COTELLIC": 1.3022006406843654, "EFAVIRENZ": 1.3956868028814229, "ENBREL": 7.753574742263338, "ENTYVIO": 1.67004583041939, "ERELZI": 7.702435262539715, "ETANERCEPT": 8.211937068420342, "EXFORGE": 1.1843309054420064, "FAMPYRA": 1.1877823446127598, "FIRDAPSE": 2.0597810317065632, "HUMIRA": 5.2420571725315765, "HYDROCORTISONE": 2.6001489732830843, "IMIQUIMOD": 13.30360113259045, "INFLIXIMAB": 1.540426244001302, "JAKAVI": 1.168753714227085, "KESIMPTA": 1.6226921266765533, "LEFLUNOMIDE": 3.305211469604857, "MENVEO": 8.721181010352149, "METFORMIN": 3.74834891863175, "METHOTREXATE": 1.82013987700272, "MMRVAXPRO": 1.2646127812102963, "MYCOPHENOLATE": 1.0805002165794946, "NAGLAZYME": 1.071767465541387, "OCRELIZUMAB": 3.799330447727375, "OMALIZUMAB": 1.7040343572460162, "OPTIMARK": 20.186883162162324, "PLEGRIDY": 1.1695763006124718, "RINVOQ": 2.6446323869119075, "RITUXIMAB": 1.211069914917214, "ROACTEMRA": 1.732731125141605, "SHINGRIX": 1.3100086413810952, "SIMPONI": 2.1807749665547336, "SKYRIZI": 1.3687164209511715, "STELARA": 1.2468131971250416, "TOZINAMERAN": 2.6730328219809256, "XELJANZ": 3.0932182395958705, "ZOSTAVAX": 1.4658882001776157, "ZYCLARA": 4.791144196106012}
\ No newline at end of file
+{"JANUMET": 12.410156959138003, "SOLIRIS": 19.18818422318626, "null": 0.6579646667343007}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4326.json
index eb90e315b25..651a48670ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4326.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4326.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 10.577831970737904, "AZATHIOPRINE": 19.92681508052921, "BUDESONIDE": 2.0872131448249704, "CICLOSPORIN": 1.658651683607138, "CIMZIA": 3.712675855536364, "COSENTYX": 64.29945591752977, "DAXAS": 167.861493551287, "ENBREL": 1.5428388153351964, "ENTYVIO": 22.88699060419961, "GARDASIL": 2.12177509232735, "HUMIRA": 6.7775644416693845, "RINVOQ": 4.429214628484195, "SIMPONI": 2.4327272292744544, "STELARA": 13.420157442534055, "XELJANZ": 2.799415557771757}
\ No newline at end of file
+{"ALEMTUZUMAB": 14.95646450630398, "AMIKACIN": 16.734222936633564, "ARAVA": 1.606872880376806, "CELLCEPT": 10.22487796714096, "CICLOSPORIN": 2.024893905368876, "FORXIGA": 19.14607435139621, "JAKAVI": 4.221589741136783, "JARDIANCE": 6.068012360036946, "METHOTREXATE": 4.665174701349785, "ROACTEMRA": 4.2103890123311, "SIMPONI": 1.9481547769557463, "SOLIRIS": 12.786681220250896, "STELARA": 1.757331660956756, "ZOSTAVAX": 3.45147015538061, "null": 0.5324652915849648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4327.json
index f9665aa0b4f..1d77c49dbfa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4327.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4327.json
@@ -1 +1 @@
-{"ABATACEPT": 3.102967102413823, "ADALIMUMAB": 1.7426444290410876, "AMIKACIN": 14.389638833673551, "ARAVA": 1.7528543892865314, "AZATHIOPRINE": 4.682405345044963, "CIMZIA": 4.701261183651728, "CLOPIDOGREL": 1.4038534165446426, "COMIRNATY": 1.2792249975720478, "COSENTYX": 2.503911933639708, "CYTARABINE": 4.390950891122365, "ENVARSUS": 179.42922398324947, "FAMPYRA": 5.808849382764881, "HUMIRA": 4.740294612246738, "JARDIANCE": 2.244689008308591, "KEYTRUDA": 1.6596974545209373, "KYMRIAH": 7.161187893129215, "RINVOQ": 3.874335321154836, "STELARA": 1.1342951047344136, "XELJANZ": 4.328035945001187}
\ No newline at end of file
+{"ARAVA": 0.6518652586299574, "BYDUREON": 6.679815282669478, "BYETTA": 7.666152884303497, "COMIRNATY": 0.1783064460444285, "ELIQUIS": 2.700314983387932, "ENTRESTO": 3.5948513258117534, "IBRANCE": 1.2874947178738327, "JANUMET": 15.537108715397943, "JANUVIA": 9.112397556056871, "LYRICA": 3.239136847301827, "SILDENAFIL": 10.50888608751662, "SPIKEVAX": 0.2519437676342549, "SUTENT": 0.763700882672659, "TASIGNA": 7.443647461291658, "TOZINAMERAN": 0.3056586136640269, "VAXZEVRIA": 0.1406966151652632, "ZOSTAVAX": 71.06535124882829, "ZYPREXA": 2.396428503018617, "null": 0.8179744460097687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4328.json
index 78d19870230..2400b716c26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4328.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4328.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.7552499721466694, "BUPRENORPHINE": 13.26306618132073, "COMIRNATY": 1.1741548353410811, "COSENTYX": 16.044364273902605, "COVID19": 1.1688307962549738, "EXFORGE": 12.254302999833044, "SPIKEVAX": 1.1761087536579269, "TOZINAMERAN": 1.7360804714887643}
\ No newline at end of file
+{"COMIRNATY": 0.3816884945997161, "VAXZEVRIA": 0.4518606905518733, "null": 0.8037916861832554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4329.json
index aae74a0243f..d5c19461e7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4329.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4329.json
@@ -1 +1 @@
-{"null": 1.1754565013842662}
\ No newline at end of file
+{"COMIRNATY": 0.7430052302246158, "CYMBALTA": 8.911536473271578, "GARDASIL": 3.599686820589099, "SPIKEVAX": 0.3890433055271787, "VAXZEVRIA": 0.2961597618599872, "null": 1.4365660284572508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/433.json
index dc1c673bde8..86cbc207b3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/433.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/433.json
@@ -1 +1 @@
-{"HUMALOG": 5.502912499872712, "HUMIRA": 11.202214953071064, "XELJANZ": 7.165849440569597}
\ No newline at end of file
+{"AIMOVIG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4330.json
index 5b6f99d7920..48fd0452048 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4330.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4330.json
@@ -1 +1 @@
-{"ADEMPAS": 1.2060706977797049, "AMBRISENTAN": 1.1566427827968857, "ANTIBIOTICS": 1.1514112226514606, "APIXABAN": 1.5812180996101095, "AXICABTAGENE": 1.5057697518850115, "BENLYSTA": 2.990435487683974, "BENRALIZUMAB": 1.7218836244412397, "CINRYZE": 1.162035601237272, "COMIRNATY": 1.7647692330212943, "COSENTYX": 1.502309459266118, "COVID19": 2.3904406625988543, "DUAKLIR": 7.5042821959927695, "ESBRIET": 1.264303172564939, "FAMPYRA": 1.166355293694121, "FASENRA": 1.7412876893073737, "FILGRASTIM": 1.062699139211459, "GALAFOLD": 1.126074357783864, "HIZENTRA": 1.3512080293252924, "HYQVIA": 1.0074061434247652, "ILARIS": 7.989167777702192, "INCRUSE": 2.1885825963465426, "INFLECTRA": 2.471487595632349, "INFLIXIMAB": 1.0135865029673294, "INSULIN": 1.1348700119996031, "JCOVDEN": 8.72604600768434, "KALYDECO": 3.195248964567396, "KESIMPTA": 2.7477400831620264, "MEPOLIZUMAB": 2.9302143865762544, "METHOTREXATE": 1.0181307285960983, "NAGLAZYME": 1.2419964811721829, "NUCALA": 1.9760176997168577, "OCRELIZUMAB": 1.5229555993015582, "OMALIZUMAB": 2.817614568065777, "OPSUMIT": 1.340756509998968, "ORENCIA": 1.708522060314618, "ORKAMBI": 4.422379182610666, "OSELTAMIVIR": 1.8395131464268355, "OZEMPIC": 1.4787226640120426, "PIOGLITAZONE": 10.12611224470729, "PLEGRIDY": 3.0891113886516446, "SIMPONI": 3.658129551757393, "SOLIRIS": 1.0972054169392556, "SPIKEVAX": 3.345594059956712, "SPINRAZA": 1.85011139009296, "STELARA": 1.0338018648703962, "SYNAGIS": 3.18294008187578, "TAMIFLU": 2.643209913670965, "TRELEGY": 1.2416273775099835, "VAXZEVRIA": 5.332203974936432, "VELTASSA": 1.252261183404716, "XELJANZ": 2.5377032796983707, "XOLAIR": 1.745148655595879, "ZINBRYTA": 1.8976420441066304}
\ No newline at end of file
+{"CANAGLIFLOZIN": 78.65079508481217, "CELECOXIB": 9.017105327801564, "DAPAGLIFLOZIN": 71.7024408889011, "EMPAGLIFLOZIN": 379.8467784748874, "FORXIGA": 83.17267985188033, "INVOKANA": 51.56630694276225, "JARDIANCE": 539.3975028057515, "null": 0.0349027208351444}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4331.json
index 69e2a8a0ce6..b887359af4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4331.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4331.json
@@ -1 +1 @@
-{"SPIKEVAX": 28.879922193631675}
\ No newline at end of file
+{"ABILIFY": 43.02828312291222, "ARIPIPRAZOLE": 65.5007457780649, "AZILECT": 15.180975836807365, "BRINTELLIX": 1.9207114956841147, "BUPRENORPHINE": 6.204583453474744, "CHAMPIX": 5.370952117558132, "COMIRNATY": 0.1228467263519476, "CYMBALTA": 1.0878537144397924, "FAMPYRA": 4.08398472079152, "FENTANYL": 4.3697906449156125, "FYCOMPA": 12.61722814648986, "KEPPRA": 1.7706770999535606, "LATUDA": 4.098198385265858, "LEVETIRACETAM": 2.157143875984096, "LYRICA": 5.308550300215815, "OLANZAPINE": 6.380174879928394, "PEGASYS": 0.4307459069513484, "POPPERS": 290.2125957149228, "SPIKEVAX": 0.1025358176235951, "SUBOXONE": 17.900787673624606, "TOZINAMERAN": 0.4558003591261088, "VAXZEVRIA": 0.2046910305293084, "VFEND": 1.1798782532961738, "ZYPREXA": 1.1935200774533818, "null": 2.009562089363539}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4332.json
index 1d96fc8da82..1844600a95a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4332.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4332.json
@@ -1 +1 @@
-{"TAMIFLU": 49.66379759870595}
\ No newline at end of file
+{"COMIRNATY": 0.4899367120012072, "null": 0.7125810523106879}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4333.json
index e2e2793fac9..03814042c61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4333.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4333.json
@@ -1 +1 @@
-{"SPIKEVAX": 27.96292819423499}
\ No newline at end of file
+{"COMIRNATY": 0.2208725860427907, "CYMBALTA": 4.301143729361999, "GARDASIL": 5.684287021508732, "IBUPROFEN": 18.003712058957543, "METHOTREXATE": 19.557125640756635, "TOZINAMERAN": 1.9520667450410965, "ZOSTAVAX": 22.70853471540661, "null": 0.9596508779679164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4334.json
index 60aa340e34c..3184e9b5786 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4334.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4334.json
@@ -1 +1 @@
-{"ALDARA": 6.745198237156695, "AVONEX": 2.308208306179784, "BESREMI": 4.603300738466763, "BETAFERON": 5.200479261848722, "BOCEPREVIR": 1.082941383370084, "BONVIVA": 3.49833481901078, "BOTULINUM": 1.696233188305625, "CERVARIX": 1.0281322092369305, "COMIRNATY": 2.410989598794739, "COVID19": 6.182112025594535, "ELASOMERAN": 2.613017390762926, "FLUCELVAX": 1.588082399100139, "IMIQUIMOD": 2.977177588933304, "INFERGEN": 2.3352455434726824, "INTERFERON": 1.6698120677224937, "INTRONA": 1.2275272601220228, "JCOVDEN": 1.0859464848205576, "KESIMPTA": 6.522479623162985, "NIMENRIX": 1.1359581729500312, "PEGASYS": 1.9477822197913448, "PEGINTERFERON": 1.3766685742326203, "PEGINTRON": 2.0285873433263046, "PLEGRIDY": 18.240420256610207, "REBIF": 1.5129995928991793, "SHINGRIX": 2.436974412323524, "SPIKEVAX": 2.058936877873601, "TOZINAMERAN": 1.079299708011803, "TWINRIX": 1.8015771868868835, "VAXZEVRIA": 4.832881116230317, "ZIAGEN": 1.1986444232209987, "ZYCLARA": 4.690176277945901}
\ No newline at end of file
+{"COMIRNATY": 0.8393977001475289, "VAXZEVRIA": 1.5706472243509972, "null": 0.4309090647495694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4335.json
index b44e25f01b9..8309518f405 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4335.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4335.json
@@ -1 +1 @@
-{"SPIKEVAX": 10.471255506495}
\ No newline at end of file
+{"null": 0.9603570280305574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4336.json
index d4f4f70b360..1b8fa553ff2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4336.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4336.json
@@ -1 +1 @@
-{"ELIQUIS": 2.1000561080311195, "INFLIXIMAB": 47.003772984888606, "SUTENT": 1.779402256077714, "null": 1.57530294472817}
\ No newline at end of file
+{"null": 0.6354253074591604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4337.json
index 69cabded08e..397d308bb10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4337.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4337.json
@@ -1 +1 @@
-{"null": 1.5306083471358174}
\ No newline at end of file
+{"null": 6.401891465944409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4338.json
index 751efeb679d..ad7deade0ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4338.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4338.json
@@ -1 +1 @@
-{"ABACAVIR": 24.46678274043601, "ABATACEPT": 8.092317732085135, "ACETAMINOPHEN": 21.988815956056705, "ACLASTA": 3.4797199909375998, "ADALIMUMAB": 17.138512223169908, "AGALSIDASE": 17.317630442395497, "AMINOSALICYLIC": 9.85698474658934, "ANAKINRA": 1.0103415449012627, "APREMILAST": 13.742923219633482, "APREPITANT": 19.524010325729176, "ARAVA": 14.73064050774406, "ARZERRA": 14.8457164984654, "ATEZOLIZUMAB": 5.885192582113821, "AVAMYS": 8.703427129513821, "AVASTIN": 1.686686161315401, "AVELUMAB": 16.322856595610713, "AXITINIB": 1.2744686066846218, "AZATHIOPRINE": 1.5650635689407528, "BAVENCIO": 30.263936496241936, "BENLYSTA": 1.933817828000707, "BORTEZOMIB": 2.0796688567753985, "BRAFTOVI": 1.0889538874222968, "BUDESONIDE": 11.422271630851982, "CAELYX": 27.69827858036788, "CARFILZOMIB": 4.64161664692704, "CIMZIA": 2.386729055641581, "CINRYZE": 9.204765678981673, "DARZALEX": 79.28832067209537, "DOCETAXEL": 1.0015939076499665, "ENBREL": 5.363018848885099, "ENTYVIO": 2.194005238893579, "ERBITUX": 8.464936897539623, "ERELZI": 4.352674538718942, "ETANERCEPT": 2.755980402086721, "FLEBOGAMMA": 14.098299361186882, "GAZYVARO": 46.704607631476414, "HERCEPTIN": 13.78088985863785, "HUMAN": 2.6396432445734037, "HUMIRA": 1.2899212108752058, "HYQVIA": 3.3763105294911497, "ILARIS": 19.021352046489564, "INFLIXIMAB": 2.560179316215295, "IPILIMUMAB": 1.5634916457620631, "KEYTRUDA": 1.5451122260923804, "KIOVIG": 6.4666658005341136, "KYPROLIS": 1.752897046994347, "LEFLUNOMIDE": 1.393898439637943, "LEMTRADA": 1.7434850552013312, "MABTHERA": 3.663189675439032, "METHOTREXATE": 2.863534061549834, "NAGLAZYME": 8.652112624932109, "OBINUTUZUMAB": 23.44582970320656, "OCRELIZUMAB": 35.30788970180757, "ONCASPAR": 2.140329760239252, "OPDIVO": 2.671359213541632, "ORENCIA": 5.1587347396241885, "PACLITAXEL": 2.0721947443348614, "PERJETA": 22.759051600025884, "PERTUZUMAB": 10.059885656161416, "POTELIGEO": 31.61374002051957, "PREGABALIN": 5.042370566723563, "PRIVIGEN": 4.275398723087484, "REMDESIVIR": 2.2953720974986123, "REMICADE": 23.21810735084618, "RITUXIMAB": 9.151837978951018, "RIXATHON": 32.75428987528744, "ROACTEMRA": 3.8298921110424806, "SOLIRIS": 1.045997378823388, "STELARA": 6.866808505768802, "SYLVANT": 10.35582239423618, "TOCILIZUMAB": 2.5674632269032647, "TORISEL": 4.113035691601546, "TRODELVY": 1.5224691187433366, "VECTIBIX": 3.268563738025764, "YERVOY": 1.2766175413971343}
\ No newline at end of file
+{"CICLOSPORIN": 18.327526838223587, "NPLATE": 88.72577118324857, "null": 0.2915769378227907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4339.json
index 06bb8ca4bd1..cd57cca0d5f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4339.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4339.json
@@ -1 +1 @@
-{"HIZENTRA": 446.1142005373127}
\ No newline at end of file
+{"FORSTEO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/434.json
index b87975dee3d..ca5d8bf5499 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/434.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/434.json
@@ -1 +1 @@
-{"OMALIZUMAB": 185.6870593965517}
\ No newline at end of file
+{"ARAVA": 2.971970738754869, "COMIRNATY": 0.5350587177746408, "ENBREL": 6.790035003120996, "TOZINAMERAN": 0.8665497565096602, "VAXZEVRIA": 0.5983615791603697, "null": 1.0102233727608827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4340.json
index 88562354f3f..e887f0e6215 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4340.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4340.json
@@ -1 +1 @@
-{"HIZENTRA": 442.32685632151816, "HUMAN": 55.42009141406299}
\ No newline at end of file
+{"ASPARAGINASE": 97.80940640266805, "FENTANYL": 24.155237298645137, "PAZOPANIB": 190.91307841316643, "null": 0.6085595404616717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4341.json
index f1686a5b5ad..bf7cf95d918 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4341.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4341.json
@@ -1 +1 @@
-{"HIZENTRA": 240.237802580342}
\ No newline at end of file
+{"null": 1.820352752819057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4342.json
index 876425f8a90..e378d481afe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4342.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4342.json
@@ -1 +1 @@
-{"HIZENTRA": 309.9111977950611, "HYQVIA": 409.8161138455493, "IBUPROFEN": 17.220507142965946}
\ No newline at end of file
+{"MMRVAXPRO": 44.1801676623634, "null": 1.671928449871968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4343.json
index 4ed86aae61d..5430c83275e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4343.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4343.json
@@ -1 +1 @@
-{"HIZENTRA": 109.28780419841054, "null": 1.6522904669258187}
\ No newline at end of file
+{"COMIRNATY": 0.2046439596506583, "TOZINAMERAN": 1.8630384977782024, "VAXZEVRIA": 0.9531012503287578, "null": 0.6770710126801391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4344.json
index cb28993ecd6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4344.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4344.json
@@ -1 +1 @@
-{"IBUPROFEN": 86.92604237483933}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4345.json
index b75d177b248..bdc9c380f2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4345.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4345.json
@@ -1 +1 @@
-{"ADEMPAS": 21.72114957276768, "ALEMTUZUMAB": 5.745024877636352, "APIXABAN": 2.6525611591279143, "FENTANYL": 1.7560300333019536, "FIASP": 41.26350511296162, "FILGRASTIM": 13.037577282455592, "HIZENTRA": 219.9994685294065, "HUMALOG": 1.29397026304927, "HUMAN": 15.62718382716889, "HYQVIA": 213.33950924423783, "IBUPROFEN": 11.357535975605902, "KYPROLIS": 21.52517691668857, "LEVOFLOXACIN": 5.242558021484332, "LYUMJEV": 378.7068424793442, "MIDAZOLAM": 7.584866298569876, "OPSUMIT": 8.782139207578485, "PRIVIGEN": 7.022568771584545, "TRACLEER": 6.628843076772189, "null": 1.5867215176361351}
\ No newline at end of file
+{"COMIRNATY": 0.1747054294448148, "CYMBALTA": 2.7489211056791096, "LEVETIRACETAM": 12.077227753748533, "OLANZAPINE": 8.234773078068882, "VAXZEVRIA": 0.2989221900499594, "null": 1.943971453952612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4346.json
index c48204ac558..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4346.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4346.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 18.968352798601163, "BONVIVA": 24.87970433586598, "DARZALEX": 12.423451496536437, "ENTYVIO": 4.644557222129218, "FENTANYL": 2.8897352579019158, "HIZENTRA": 15.37860710175936, "ILARIS": 144.8934447434867, "KEYTRUDA": 2.272790940798313, "KYPROLIS": 133.22205638618416, "NAGLAZYME": 25.48472702528333, "PRIVIGEN": 13.581766027170556, "REMDESIVIR": 58.33157472813883, "SITAGLIPTIN": 175.88972800076286, "YONDELIS": 170.21029631779604, "null": 2.7848923619466923}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4347.json
index 443d6c72791..6b8544f76c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4347.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4347.json
@@ -1 +1 @@
-{"null": 4.689831001001493}
\ No newline at end of file
+{"FAMPRIDINE": 811.0982281260475, "null": 1.1560963091768817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4348.json
index d581be40e06..1eb0db42793 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4348.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4348.json
@@ -1 +1 @@
-{"null": 1.1821588320254246}
\ No newline at end of file
+{"null": 0.6017316018275947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4349.json
index dedc0d83060..536d51d6a63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4349.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4349.json
@@ -1 +1 @@
-{"ELIQUIS": 11.553040939302468, "HIZENTRA": 109.82311609014116, "HUMAN": 69.15047975926672, "LYUMJEV": 262.73610743808274, "OPSUMIT": 12.166212180259745}
\ No newline at end of file
+{"null": 3.484806290653003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/435.json
index d9ffedcea8b..86cbc207b3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/435.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/435.json
@@ -1 +1 @@
-{"JARDIANCE": 33.62096270061436, "SPIKEVAX": 4.402474394814995}
\ No newline at end of file
+{"AIMOVIG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4350.json
index e0942f72557..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4350.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4350.json
@@ -1 +1 @@
-{"null": 1.1422885138152594}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4351.json
index d8fb875c4a5..2036583fd21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4351.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4351.json
@@ -1 +1 @@
-{"HIZENTRA": 163.63267015910438, "IBUPROFEN": 68.49313046470938, "LYUMJEV": 1638.7925262499334}
\ No newline at end of file
+{"COMIRNATY": 0.1632621268399701, "null": 4.211344204441964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4352.json
index f2636fede14..854a231aaba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4352.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4352.json
@@ -1 +1 @@
-{"ADEMPAS": 120.68576651036204, "HIZENTRA": 116.33437722823396, "HUMALOG": 6.38068917777827, "OPSUMIT": 40.25640677337759, "null": 1.0567799158588862}
\ No newline at end of file
+{"null": 0.855331966490197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4353.json
index d383838311c..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4353.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4353.json
@@ -1 +1 @@
-{"FIASP": 117.99053270573027, "HIZENTRA": 68.76974051101088, "LYUMJEV": 835.8845780395651, "null": 2.7021461556511475}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4354.json
index 6f3007db52a..c1f6de169b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4354.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4354.json
@@ -1 +1 @@
-{"CRESEMBA": 535.8320072993289, "HIZENTRA": 108.78686453360515, "IBUPROFEN": 29.044063949630686, "OPSUMIT": 29.90641575581305}
\ No newline at end of file
+{"ARIPIPRAZOLE": 36.90440477866854, "COMIRNATY": 0.3316014461594616, "LANTUS": 9.156209584204955, "null": 1.0111312736806846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4355.json
index cf86563c1d9..755cb2bf69e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4355.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4355.json
@@ -1 +1 @@
-{"BUPIVACAINE": 273.9821206216226, "FENTANYL": 23.9578032001368, "HIZENTRA": 170.6550307713755}
\ No newline at end of file
+{"ADCIRCA": 4.6828264657273495, "ALISKIREN": 41.09016130330909, "ATRIPLA": 1.4807774079884015, "AVAMYS": 2.650386578731527, "AVANDIA": 0.5092105426149997, "BUDESONIDE": 1.3152964193521666, "CLOPIDOGREL": 0.924078511165896, "COMIRNATY": 3.75221354493744, "DULOXETINE": 1.949505244762897, "ELIQUIS": 0.5045740967492736, "ENTRESTO": 3.177245322363361, "GARDASIL": 4.873134633713202, "LANTUS": 0.2815315042282526, "MELATONIN": 4.116199177470562, "MEPOLIZUMAB": 1.0937810917223891, "NUCALA": 2.5725317728028347, "OFEV": 1.594976787253541, "OMALIZUMAB": 0.7957006915303726, "OPSUMIT": 2.081498638341815, "PANTOPRAZOLE": 5.140933144337856, "PLAVIX": 0.3682412306374267, "REVATIO": 1.4671564844320633, "SILDENAFIL": 2.0930993515053293, "SPIKEVAX": 2.069156505426191, "SPIRONOLACTONE": 3.2828705842567687, "TOZINAMERAN": 0.745065579954156, "TRACLEER": 3.0743131068499108, "TRUVADA": 0.7805624354168673, "VALSARTAN": 4.891973175554948, "VAXZEVRIA": 0.8322526930517915, "XELJANZ": 0.2697247520573495, "ZOSTAVAX": 0.4269217543291971, "null": 0.339896628379122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4356.json
index b4fd5988732..43b57c26dc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4356.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4356.json
@@ -1 +1 @@
-{"COMIRNATY": 1.99002704542312}
\ No newline at end of file
+{"COMIRNATY": 2.220624727706924, "VAXZEVRIA": 2.165391210196564, "null": 0.1827995417879182}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4357.json
index c4b80164b13..07872e9dda9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4357.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4357.json
@@ -1 +1 @@
-{"null": 2.4699264535838386}
\ No newline at end of file
+{"COMIRNATY": 0.2452706590947578, "CYMBALTA": 3.069331270634832, "FYCOMPA": 17.966812824868196, "ICLUSIG": 8.586620657294072, "KEPPRA": 1.804561498976743, "KEYTRUDA": 1.782841531385605, "NEXAVAR": 2.618476216275731, "OPTIMARK": 27.09456818059071, "SPIKEVAX": 0.1678941786322082, "TOZINAMERAN": 0.6688702616259021, "VAXZEVRIA": 0.1686836709884223, "null": 1.4786950871698803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4358.json
index 8c2ce3fb0f1..91f607b2cac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4358.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4358.json
@@ -1 +1 @@
-{"HIZENTRA": 992.904496928134}
\ No newline at end of file
+{"null": 1.7549413295032312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4359.json
index a86cd7aa75b..61219823aa0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4359.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4359.json
@@ -1 +1 @@
-{"HIZENTRA": 49.51602992480217, "null": 3.111937376872949}
\ No newline at end of file
+{"ASPARAGINASE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/436.json
index 6d068350f34..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/436.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/436.json
@@ -1 +1 @@
-{"null": 1.1662753394176235}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4360.json
index 9a693437394..fdc5bb9cbd4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4360.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4360.json
@@ -1 +1 @@
-{"ADEMPAS": 51.3638777441586, "ALEMTUZUMAB": 5.901168180737076, "ENTYVIO": 3.2856747155776302, "FIASP": 120.95654899212178, "HIZENTRA": 116.9425723282699, "HUMALOG": 1.8712050117879544, "HUMAN": 13.520994382603185, "HYQVIA": 200.52019454525885, "IBUPROFEN": 8.819957091522008, "KYPROLIS": 35.94145743829901, "LYUMJEV": 1479.5861239778103, "OPSUMIT": 17.139914461970182, "TRACLEER": 5.363027835015031, "null": 1.5786514717531963}
\ No newline at end of file
+{"APTIVUS": 901.5852294731764, "null": 3.626610771057925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4361.json
index d348bff2409..e9e2bff601e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4361.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4361.json
@@ -1 +1 @@
-{"null": 1.7813829783242132}
\ No newline at end of file
+{"ALEMTUZUMAB": 9.127196797719863, "CICLOSPORIN": 2.367556079221627, "COMBIVIR": 26.24100695540829, "COMIRNATY": 0.2971528311195056, "DEXAMETHASONE": 3.1524336234019006, "KEPPRA": 3.3285676716224857, "SPIKEVAX": 0.2379796425377422, "SUTENT": 0.9122648233046168, "TOZINAMERAN": 0.9501043563721294, "VAXZEVRIA": 0.1767217817177687, "null": 1.5891718543349038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4362.json
index dbfbb3cf0cc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4362.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4362.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 15.2608525292957, "null": 6.692700128478317}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4363.json
index ddeab6e4281..1854da5c9c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4363.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4363.json
@@ -1 +1 @@
-{"ADEMPAS": 52.15594348002582, "FIASP": 48.44348166416366, "HIZENTRA": 261.2755060893157, "HUMAN": 24.884685448179056, "HYQVIA": 105.6526710566351, "IBUPROFEN": 8.312179719830008, "LEVOFLOXACIN": 6.848978721640928, "LYUMJEV": 468.8194607652781, "OPSUMIT": 9.688391800438271, "null": 1.2928576341841371}
\ No newline at end of file
+{"ABATACEPT": 20.161274679174117, "ADALIMUMAB": 10.68683980553677, "ARAVA": 13.483474909926564, "ATRIPLA": 1.7104483811358708, "BOTULINUM": 10.239844109786985, "BYETTA": 2.0948461308653394, "CERTOLIZUMAB": 61.60156459260583, "CHOLESTAGEL": 169.81984144562443, "CIMZIA": 1.549305099121424, "CLOPIDOGREL": 0.9122742013705792, "COMIRNATY": 0.0319317480930821, "ELIQUIS": 0.7176966665224755, "ENBREL": 2.977859028139469, "FORSTEO": 1.068111074388186, "HUMALOG": 1.535604406737893, "HUMIRA": 2.8047207775240683, "IBRANCE": 1.3295829721979922, "LANTUS": 1.1443222090719365, "LEFLUNOMIDE": 31.017502864808364, "LEVOFLOXACIN": 1.965382380471534, "LYRICA": 2.441455230714451, "PEGASYS": 0.3826926735596139, "SIMPONI": 3.624010368856305, "SPIKEVAX": 0.049702650549131, "STELARA": 0.733592711960113, "STRIBILD": 1.977521717733416, "TRUVADA": 1.8777921401791624, "VIAGRA": 2.030754037177817, "XELJANZ": 2.3877698561179064, "ZOSTAVAX": 1.627314342759537, "null": 0.6698358970209854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4364.json
index 655a68b5aac..2057f6f84f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4364.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4364.json
@@ -1 +1 @@
-{"HIZENTRA": 137.91807049067268, "null": 1.6040519479099495}
\ No newline at end of file
+{"null": 0.7934161955149596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4365.json
index b6411510ccb..e8bec2b5dfb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4365.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4365.json
@@ -1 +1 @@
-{"ABATACEPT": 142.6571936681913, "ADALIMUMAB": 7.183793956895422, "ADEMPAS": 31.05025116633616, "CAELYX": 16.34110469836217, "ENBREL": 4.003917278550165, "HIZENTRA": 41.18562855320863}
\ No newline at end of file
+{"ALEMTUZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4366.json
index 9eda45a0d54..952437c30cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4366.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4366.json
@@ -1 +1 @@
-{"HIZENTRA": 506.3751079093613}
\ No newline at end of file
+{"AUBAGIO": 40.421150494783, "BETAFERON": 263.1656190182535, "IRBESARTAN": 97.23315952462826, "LEMTRADA": 95.1796241988632, "MAVENCLAD": 722.1823674853553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4367.json
index 7224fb3411f..425edd19760 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4367.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4367.json
@@ -1 +1 @@
-{"ADEMPAS": 34.219016949031506, "ELIQUIS": 1.083257393159973, "FILGRASTIM": 18.66190562131812, "HIZENTRA": 264.04880842210986, "HYQVIA": 191.9980464667072, "IBUPROFEN": 15.730499965745548, "LYUMJEV": 121.98537586232004, "NAGLAZYME": 29.761105911720964, "OPSUMIT": 13.12940867982921, "PRIVIGEN": 8.981761725849443, "null": 1.6893996363064043}
\ No newline at end of file
+{"null": 0.9518920967503458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4368.json
index 0b1e98355eb..144cff2c705 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4368.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4368.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 247.64097312952595, "null": 1.60774237993182}
\ No newline at end of file
+{"APIDRA": 22.92441018192392, "LANTUS": 30.083697025656587, "NOVORAPID": 48.99224621572243, "null": 2.095527754009103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4369.json
index 5d4ae5ac8d6..da80c738bdf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4369.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4369.json
@@ -1 +1 @@
-{"HIZENTRA": 397.2090663079029, "null": 1.000143026188907}
\ No newline at end of file
+{"ABILIFY": 1.200878556062303, "AERIUS": 4.133211709464831, "ANORO": 2.292434119589378, "APIDRA": 14.901815873537812, "BUDESONIDE": 0.5112400952264291, "BYETTA": 0.9846649118909118, "COMIRNATY": 0.0716331672518148, "CYMBALTA": 0.3626577032294938, "DAPTOMYCIN": 34.2054777324708, "ELIQUIS": 0.2113489347733853, "EXFORGE": 2.1088754075213507, "FORSTEO": 0.5744715046943557, "GARDASIL": 0.6575594505737892, "GLUCAGON": 29.898897788173056, "HUMALOG": 8.425662931325101, "IBRANCE": 0.4866872771462147, "INSULIN": 2.054620886081299, "JANUMET": 1.5694249398837288, "KEPPRA": 0.5128800912861822, "KEYTRUDA": 0.422271991036725, "LANTUS": 6.526913072197282, "LEVEMIR": 4.756112543938508, "LYRICA": 0.6713838638576742, "LYUMJEV": 15.131490389792624, "MMRVAXPRO": 1.3056771681502553, "NIMENRIX": 1.2112663635838743, "NOVORAPID": 3.8457380988723378, "RAPAMUNE": 5.438286052108444, "RELVAR": 3.996726633513987, "REVATIO": 7.164953475073436, "ROACTEMRA": 0.8454459607050187, "ROTATEQ": 2.38477974434178, "SAXENDA": 1.0809850887502903, "SPIKEVAX": 0.8130422288311516, "SUTENT": 0.2578601105829613, "TAMIFLU": 1.31278252230642, "TOUJEO": 3.7689565369952063, "TOVIAZ": 3.0213527704479746, "TOZINAMERAN": 0.2962614421605223, "TRELEGY": 1.6860510214395368, "TRULICITY": 0.8490297113211839, "TWINRIX": 2.4592835847579297, "VAXZEVRIA": 0.0624361591003618, "VIAGRA": 4.4169697621793125, "XELJANZ": 0.5955116678869312, "ZOSTAVAX": 0.5898569446075218, "null": 3.440374437064773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/437.json
index 89719ba1753..f7025a4bc91 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/437.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/437.json
@@ -1 +1 @@
-{"JARDIANCE": 5.178923155646612, "LAMIVUDINE": 32.785953755349425, "LEVOFLOXACIN": 6.3262374118929445, "null": 2.167810359253016}
\ No newline at end of file
+{"COMIRNATY": 0.5121001934316977, "TOZINAMERAN": 1.5057005279265627, "null": 3.386877538512651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4370.json
index 533f8f28b64..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4370.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4370.json
@@ -1 +1 @@
-{"HIZENTRA": 296.54364937158067, "null": 1.7852607487944887}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4371.json
index 2bc4a16ed8e..ff709444b77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4371.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4371.json
@@ -1 +1 @@
-{"HIZENTRA": 126.37602513076978, "null": 1.3072808816042267}
\ No newline at end of file
+{"AFINITOR": 42.05382949677738, "BONVIVA": 165.77897804957803, "SUTENT": 18.61562798206001}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4372.json
index 2b55ec7d61e..8cf8cff5097 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4372.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4372.json
@@ -1 +1 @@
-{"HIZENTRA": 263.4540219891296, "OPSUMIT": 21.855279499912218, "null": 1.25258778397103}
\ No newline at end of file
+{"ABACAVIR": 21.520575829574344, "ABATACEPT": 0.7027119243026645, "ABILIFY": 0.6028719630419661, "ACTRAPID": 3.7082263932184256, "ADALIMUMAB": 4.545346793071274, "ADCIRCA": 0.6707090312035663, "AERIUS": 2.664415396680807, "AIMOVIG": 0.0977503844028785, "ALEMTUZUMAB": 0.2205382623675776, "ALL": 2.3168431560993987, "AMBRISENTAN": 0.9426722121805212, "AMIKACIN": 0.5620126647477379, "AMINOSALICYLIC": 0.8883424996650593, "ANTIBIOTICS": 4.752764445805536, "APIDRA": 3.5262143672376656, "APREMILAST": 1.4926407725579294, "APROVEL": 0.5644606160975245, "APTIVUS": 5.743266026759097, "ARANESP": 0.1396134272248966, "ARAVA": 1.895014564051908, "ARIPIPRAZOLE": 0.3398713939450438, "ARIXTRA": 4.472023273172317, "ATAZANAVIR": 1.4474691162897146, "ATOSIBAN": 12.760720574698691, "AUBAGIO": 2.3049688225369023, "AVONEX": 1.8546430804677203, "AZATHIOPRINE": 2.6770912480936784, "BEDAQUILINE": 0.686996364848804, "BENLYSTA": 1.6182449444853817, "BENZODIAZEPINE": 1.417476492188622, "BETAFERON": 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0.4899480377760857, "SILDENAFIL": 1.495686425096657, "SIMPONI": 1.4708108598533258, "SOLIRIS": 4.946387181722742, "SPIKEVAX": 0.0669153288831375, "STELARA": 5.393185795504919, "SUBOXONE": 10.919153075500306, "SUFENTANIL": 3.6708429368905486, "TACROLIMUS": 1.4733232034929953, "TAMIFLU": 1.2665863942217224, "TASIGNA": 0.1592454333248745, "TIVICAY": 1.430294539014504, "TOUJEO": 1.4684386799892766, "TOZINAMERAN": 0.1088335184942597, "TRACLEER": 0.197658678371998, "TRACTOCILE": 7.37755324372561, "TREMFYA": 2.036383649706411, "TRESIBA": 1.1856073101236613, "TRIUMEQ": 2.17369320775612, "TRUVADA": 0.0212395342441104, "VAXZEVRIA": 0.0626287793490829, "VICTOZA": 0.5925782359048675, "VIGABATRIN": 2.4990749426151813, "VIMPAT": 0.4406204105798686, "VIREAD": 0.2459991362887736, "XOLAIR": 1.1897697628159445, "ZOELY": 46.89507925655583, "ZONISAMIDE": 4.932643594157653, "ZOSTAVAX": 0.0948500257289145, "ZYPREXA": 1.7359681806096352, "null": 1.8544865652375715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4373.json
index 25030f90eff..31b6c322108 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4373.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4373.json
@@ -1 +1 @@
-{"AFINITOR": 17.27073874395147, "CRIXIVAN": 46.29286137177991, "CYMBALTA": 4.582940686822915, "EVEROLIMUS": 55.71051236674529, "IRESSA": 21.533846927067938, "SIMPONI": 4.876522769649607, "SUTENT": 3.779585730062008}
\ No newline at end of file
+{"ZOSTAVAX": 127.74107307333392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4374.json
index 2af00f94e69..3dc7dccf969 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4374.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4374.json
@@ -1 +1 @@
-{"BIKTARVY": 73.6878714520271}
\ No newline at end of file
+{"CIMZIA": 6.633551718025674, "COMIRNATY": 0.1982461413233123, "MEPOLIZUMAB": 45.95187635567599, "SPIKEVAX": 4.558470857228003, "TOZINAMERAN": 5.353682773740538, "VAXZEVRIA": 0.1514034284629566, "XELJANZ": 3.707403937381688, "null": 0.1950521871458861}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4375.json
index 45e98afbd40..5eeca87cf06 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4375.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4375.json
@@ -1 +1 @@
-{"ASPARAGINASE": 11.00472420069494, "BELANTAMAB": 398.911522618452, "BYETTA": 3.1636220843315157, "COMBIVIR": 5.414505842323663, "COSENTYX": 1.1210377867427983, "CYMBALTA": 1.2531439174619543, "ELIQUIS": 2.6250916000960345, "FORSTEO": 8.07887824496958, "JANUMET": 8.934001137597342, "JANUVIA": 5.109310757510031, "NAGLAZYME": 19.263277958292253, "SIMPONI": 1.9407015251840256, "STELARA": 1.2244320614848792, "SUTENT": 2.2976566249673835, "SYNAGIS": 12.191743656025077, "TRACTOCILE": 71.60826009645038, "XELJANZ": 1.0087804554282105, "ZOSTAVAX": 2.382894456960552, "null": 1.7140923628939555}
\ No newline at end of file
+{"OMALIZUMAB": 134.8784973278876, "null": 0.5779442939459161}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4376.json
index 253044f42e3..a5f009a0058 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4376.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4376.json
@@ -1 +1 @@
-{"ACLIDINIUM": 924.4685547655546}
\ No newline at end of file
+{"null": 1.9854724512375372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4377.json
index 08297b6ed79..de0d16ce913 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4377.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4377.json
@@ -1 +1 @@
-{"null": 19.0111691735073}
\ No newline at end of file
+{"null": 0.6203285043946399}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4378.json
index aac84d3b5b6..2ec737e16c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4378.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4378.json
@@ -1 +1 @@
-{"ADVATE": 3940.9703485076943, "KOGENATE": 5583.317080444805}
\ No newline at end of file
+{"null": 2.385337206579049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4379.json
index dcdb32a5c23..24241a6843e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4379.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4379.json
@@ -1 +1 @@
-{"ADVATE": 1497.021142300464}
\ No newline at end of file
+{"null": 1.4853773445371572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/438.json
index 0fecff80b00..e132750e7e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/438.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/438.json
@@ -1 +1 @@
-{"BENZODIAZEPINES": 190.05902887406697, "FENTANYL": 8.32515792633657, "KEPPRA": 2.8629642013006724, "null": 2.114220728310066}
\ No newline at end of file
+{"null": 1.603923508799126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4380.json
index 9c1dbcb7cc3..778f4aad1f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4380.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4380.json
@@ -1 +1 @@
-{"ANAKINRA": 10.521451883489991, "BUDESONIDE": 3.437052385875562, "KEPPRA": 3.3930176656304183, "SODIUM": 199.73286981245587, "TIVICAY": 40.90244930920812, "null": 2.2362220639573427}
\ No newline at end of file
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4381.json
index 2eaaeec308f..7bb1bd7e7f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4381.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4381.json
@@ -1 +1 @@
-{"AIMOVIG": 2.2405672739137503, "ARIPIPRAZOLE": 1.3996481925162223, "AUBAGIO": 1.1218996815691284, "AVAMYS": 1.7442243627179752, "BIKTARVY": 6.7353978046103, "BRINTELLIX": 8.705332722646437, "CHAMPIX": 1.7773419614214914, "CIRCADIN": 12.786826748189362, "COMIRNATY": 1.3873872708424473, "CYMBALTA": 1.3022591988219252, "FAMPYRA": 2.773036240892231, "FORSTEO": 1.724110145367279, "GARDASIL": 2.699538546551396, "KAFTRIO": 21.773676748792305, "KEPPRA": 1.7514922138268931, "LATUDA": 2.301809176501264, "MELATONIN": 10.813275526940268, "OLANZAPINE": 1.79538798080407, "VORICONAZOLE": 5.681869399632131, "XTANDI": 1.892253192391348, "XYREM": 12.422226735229687, "ZYPREXA": 1.2685238431321937, "null": 1.3866229930500134}
\ No newline at end of file
+{"null": 3.0340752683655694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4382.json
index fbcb03e342d..36a2f34e9c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4382.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4382.json
@@ -1 +1 @@
-{"COMIRNATY": 5.63747618979328, "COVID19": 1.5291015948064748, "GARDASIL": 2.321739191336306, "MENVEO": 9.48919609341109, "MMRVAXPRO": 2.752424731916186, "NIMENRIX": 3.33883993661782, "SHINGRIX": 10.441437278510396, "SPIKEVAX": 4.654410079293224, "TWINRIX": 4.11674735948964, "VAXZEVRIA": 1.684486676805065}
\ No newline at end of file
+{"null": 4.799161565403609}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4383.json
index eb6d8586b29..d81b9e4d2a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4383.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4383.json
@@ -1 +1 @@
-{"COVID19": 4.504651426038966, "SUBSTANCE": 13466.474301417627}
\ No newline at end of file
+{"BARACLUDE": 202.87908817627135, "PEGASYS": 2.433652797289394, "PEGINTRON": 27.624750342598524, "null": 1.8366489950988625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4384.json
index 6ead7699ca4..6b49a398a73 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4384.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4384.json
@@ -1 +1 @@
-{"COVID19": 20.9037203314345, "KESIMPTA": 41.89252635681664, "METHOTREXATE": 2.80183805109018, "SIMPONI": 2.143739096956063, "ZYPADHERA": 30.009545814606085}
\ No newline at end of file
+{"ABILIFY": 3.3094446586538617, "AIMOVIG": 0.5900616939989579, "APIDRA": 4.679269679611808, "BUPIVACAINE": 11.282454229098638, "BUPRENORPHINE": 39.0658361165897, "BUVIDAL": 41.70322730908055, "CIMZIA": 5.600649890041035, "COMIRNATY": 1.0163940313808173, "CYMBALTA": 0.888730764042262, "ELLAONE": 6.543293460583357, "ENOXAPARIN": 9.155134733725795, "FENTANYL": 0.9455220302616912, "HUMALOG": 2.8078786467384576, "IBUPROFEN": 0.8806255409288642, "KEPPRA": 4.811605304682174, "LANTUS": 1.1818561761134074, "LATUDA": 1.6386034941865268, "LEVEMIR": 3.894602312382293, "LEVETIRACETAM": 1.6035411417976884, "MELATONIN": 4.426822712663907, "MIDAZOLAM": 2.167705637984263, "OLANZAPINE": 0.6340890936153696, "OPIATES": 155.96923786553293, "OPIOIDS": 51.87075023362419, "SOLIRIS": 2.735350139679372, "SPIKEVAX": 0.8516981231245637, "STELARA": 1.256794894594688, "SUBOXONE": 54.03878760027632, "TOZINAMERAN": 1.888144529938421, "VAXZEVRIA": 0.3131749904947477, "ZYPREXA": 1.6737919223148203, "null": 0.9254809749726358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4385.json
index 05d4d0ff4e3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4385.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4385.json
@@ -1 +1 @@
-{"ACTRAPID": 19.445792850003738, "APIDRA": 5.370000190017354, "BETAFERON": 192.44242192436116, "BUVIDAL": 90.3706894690186, "BYDUREON": 24.50498032692051, "FASLODEX": 5.593973629299978, "INSULIN": 4.346093497176509, "LANTUS": 1.3942397936605522, "MIXTARD": 68.76364098067428, "PEGINTRON": 9.707400605901418, "SUBOXONE": 4.1172953446477125, "ZYPADHERA": 105.09789913813586, "null": 1.8751798223371456}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4386.json
index 64e4c9ecbec..b60aa75303d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4386.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4386.json
@@ -1 +1 @@
-{"null": 1.659913266071359}
\ No newline at end of file
+{"null": 4.382180287286969}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4387.json
index e9bfa757179..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4387.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4387.json
@@ -1 +1 @@
-{"null": 1.921723426875465}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4388.json
index dc4d4e97e3b..2d86e92da02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4388.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4388.json
@@ -1 +1 @@
-{"APIDRA": 10.28397994628966, "BETAFERON": 94.60407854944586, "FIASP": 58.30545838476363, "HUMALOG": 5.540786619491613, "INSULIN": 59.3583778629965, "LANTUS": 7.505751393557008, "LEVEMIR": 93.30764804742874, "NOVORAPID": 68.0236216001251, "SOMATROPIN": 88.83987535467666}
\ No newline at end of file
+{"null": 4.394498600569006}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4389.json
index 09927ee0db3..f733f02e757 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4389.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4389.json
@@ -1 +1 @@
-{"ABASAGLAR": 11.780928036942004, "ACLASTA": 13.30794375957594, "AIMOVIG": 4.126477337170444, "APIDRA": 6.9708808808052725, "ARANESP": 1.3467219705289228, "BENLYSTA": 4.221267432906119, "BETAFERON": 8.995978415991233, "BYDUREON": 18.59734936713588, "BYETTA": 3.464263353827132, "CIMZIA": 2.539293763525705, "COSENTYX": 5.116924717067456, "DULOXETINE": 1.460144154952685, "ENBREL": 7.9123858164873395, "ENOXAPARIN": 4.311507089019624, "EVENITY": 3.1019959216213184, "EVISTA": 18.331199522342416, "FASLODEX": 4.192591382421722, "FIASP": 8.974130740769215, "FORSTEO": 17.679281144932983, "HIZENTRA": 2.144302958553334, "HUMALOG": 7.220277265172006, "HUMIRA": 2.715843135814292, "INHIXA": 30.02566080062492, "INSULIN": 3.16320127948626, "LANTUS": 8.494217211338384, "LEVEMIR": 9.22956943458334, "LYUMJEV": 27.97931356491879, "NOVORAPID": 1.402679046895732, "NUCALA": 1.0569232766853311, "OMALIZUMAB": 6.12299501848918, "OMNITROPE": 14.132800957583653, "PEGASYS": 3.0045083914284625, "PEGINTRON": 1.18004339706036, "PLEGRIDY": 26.013201988495783, "REBIF": 15.851783606178689, "ROACTEMRA": 1.5627372233707102, "SAXENDA": 17.658288170524308, "SHINGRIX": 1.1694050285872812, "SIMPONI": 3.449766689459083, "SOMATROPIN": 10.547298936069764, "SOMAVERT": 42.68564604487056, "TERROSA": 42.52910538142604, "TOUJEO": 9.702491641405846, "TREMFYA": 1.493582058306633, "TRULICITY": 12.956717524805022, "VICTOZA": 5.8323701484702735, "XOLAIR": 1.4777847265480313, "null": 1.2475385216572106}
\ No newline at end of file
+{"null": 2.6954849018187272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/439.json
index ac4a2490d5f..f7931742243 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/439.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/439.json
@@ -1 +1 @@
-{"null": 1.1894899744046088}
\ No newline at end of file
+{"COMIRNATY": 1.5416618430037392, "VAXZEVRIA": 0.9167475988031808, "null": 0.8164544188692073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4390.json
index f9357423874..6f76bcb3c3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4390.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4390.json
@@ -1 +1 @@
-{"BETAFERON": 88.50121750688037, "BYDUREON": 26.736766198483966, "FASLODEX": 11.169839919279951, "PEGASYS": 1.949805081057718, "PEGINTRON": 13.684776272772432, "SHINGRIX": 6.530320765352262, "ZOSTAVAX": 9.622572306495094, "null": 1.3145349332440874}
\ No newline at end of file
+{"COSENTYX": 33.005856982802364, "VIAGRA": 32.05030219137888, "null": 0.7668983925861758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4391.json
index 4742d6f2b07..62a3c9ce782 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4391.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4391.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.0650614175578, "null": 1.1944206687506744}
\ No newline at end of file
+{"BENLYSTA": 92.24110670668782, "MMRVAXPRO": 5.141620923760652, "NUCALA": 68.97919537889388, "PEGASYS": 2.6800920082488298, "ROACTEMRA": 13.948521189002262, "SIMPONI": 8.896615825179344, "null": 1.0031500868476686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4392.json
index 7ad50ed925f..5f25f214d09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4392.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4392.json
@@ -1 +1 @@
-{"BYDUREON": 67.69157934369878, "FASLODEX": 71.52175056452691}
\ No newline at end of file
+{"LOXAPINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4393.json
index ebe33ed6a06..d0cefa9c677 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4393.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4393.json
@@ -1 +1 @@
-{"COVID19": 2.3496774879422597}
\ No newline at end of file
+{"null": 10.330806197681452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4394.json
index b3bd4a9546f..10dcc9cea6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4394.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4394.json
@@ -1 +1 @@
-{"null": 1.0215285781228296}
\ No newline at end of file
+{"NOVOSEVEN": 960.9056807734388, "null": 0.7490752755497724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4395.json
index 1a1b0492708..3da59600997 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4395.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4395.json
@@ -1 +1 @@
-{"BYDUREON": 82.56665540457304, "COSENTYX": 9.428336623359266, "ENTYVIO": 98.52879303103236, "HIZENTRA": 22.38434433456228}
\ No newline at end of file
+{"VORICONAZOLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4396.json
index 456bf3406fc..16485c39974 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4396.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4396.json
@@ -1 +1 @@
-{"APIDRA": 15.114670136864794, "BETAFERON": 49.09361632465938, "BYDUREON": 16.6824662529012, "CICLOSPORIN": 1.4503150673334164, "CIMZIA": 17.048523272022646, "COSENTYX": 1.9395232446659647, "ENBREL": 3.8228625315288856, "FORSTEO": 4.862508655464087, "INSULIN": 2.850513707230089, "LANTUS": 10.297137879674729, "LEVEMIR": 8.485966240901787, "PEGASYS": 1.937514477488942, "PEGINTRON": 3.286596304190232, "PLEGRIDY": 46.16490830184277, "SAXENDA": 28.08518741703107, "SHINGRIX": 5.046640069872426}
\ No newline at end of file
+{"BRINTELLIX": 0.8740373126498704, "COMIRNATY": 3.7846611311652536, "GARDASIL": 0.275148521747098, "MENVEO": 15.1349492679496, "MMRVAXPRO": 2.941809985853985, "NIMENRIX": 5.430038249084654, "SHINGRIX": 2.7875279290666524, "SPIKEVAX": 11.729198809630306, "TWINRIX": 1.6015864549640146, "VAXZEVRIA": 1.6707638819333626, "null": 0.0304723529063225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4397.json
index 7dbae94fe49..2fa1e7b1dc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4397.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4397.json
@@ -1 +1 @@
-{"AIMOVIG": 1.922128033506088, "BYDUREON": 4.841349528049299, "COMIRNATY": 2.468223417533542, "COVID19": 1.9949735224601095, "EYLEA": 5.255075021735088, "FASLODEX": 7.944307935574326, "FORSTEO": 2.190581797628984, "HIZENTRA": 3.222536202910875, "LANTUS": 1.774472970713241, "MMRVAXPRO": 2.01908748162016, "NIMENRIX": 7.488189960521683, "NUCALA": 3.307850509837743, "SAXENDA": 2.469739815846446, "SHINGRIX": 2.602954285544476, "SPIKEVAX": 3.050744018309254, "TRULICITY": 5.248700777235031, "XOLAIR": 1.1579158221467043}
\ No newline at end of file
+{"CICLOSPORIN": 4.014941467335468, "FENTANYL": 3.928810594244136, "MIDAZOLAM": 28.576773696516508, "VAXZEVRIA": 0.1465089667123558, "null": 3.220882603233773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4398.json
index f0095946354..9bf7db388e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4398.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4398.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.1638517789902854, "AIMOVIG": 1.7117656360986115, "BETAFERON": 6.455033157458272, "BEXSERO": 1.05089050728432, "BUVIDAL": 11.58112562317231, "BYDUREON": 2.384277727697458, "CERVARIX": 1.7107760528989084, "COMIRNATY": 2.154836137268935, "COVID19": 1.6602724265988749, "ENTYVIO": 1.5896692452638743, "EVENITY": 2.879290018259928, "EVISTA": 1.442910248339064, "FASLODEX": 1.041429760818284, "FIASP": 1.816624770436575, "FLUCELVAX": 1.0525761507824511, "FORSTEO": 4.886822139028914, "HIZENTRA": 3.5978678448564683, "HYQVIA": 3.963701915684325, "IDACIO": 2.5795402305388357, "INFANRIX": 2.9684648264043227, "INHIXA": 2.801516410221856, "INSULATARD": 1.6231185977504778, "JCOVDEN": 1.631260259674952, "KESIMPTA": 1.2198683777733206, "LEVEMIR": 4.857376712430522, "LYUMJEV": 13.669935236693926, "MENQUADFI": 9.239081312419753, "MENVEO": 5.153677110621563, "MIXTARD": 1.2501375863977937, "MMRVAXPRO": 7.60287510516651, "MOVYMIA": 7.8839659616020095, "NIMENRIX": 7.454712751021688, "PEGINTRON": 1.0414890306633455, "PLEGRIDY": 21.834867401333877, "PREVENAR": 1.4309719046358644, "REBIF": 3.518185216469681, "ROACTEMRA": 2.258374685064464, "ROTARIX": 4.666092149636292, "SAXENDA": 9.519961246906144, "SHINGRIX": 5.500099841118324, "SPIKEVAX": 8.616017183577258, "TERIPARATIDE": 1.2184461615198017, "TERROSA": 4.430756947462962, "TREMFYA": 1.6455740972454884, "TRULICITY": 5.224260525478492, "TWINRIX": 1.9344551180634653, "VAXZEVRIA": 1.1170824173589338, "VICTOZA": 1.6623401455413327, "XOLAIR": 1.1078238134720362}
\ No newline at end of file
+{"CELLCEPT": 96.94836619722362, "null": 0.753124490853024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4399.json
index 0b20d1c81f8..5e80a70b921 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4399.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4399.json
@@ -1 +1 @@
-{"AIMOVIG": 9.79943382609506, "BONVIVA": 12.000684036178717, "BYDUREON": 90.09055393472178, "BYETTA": 5.433490753360112, "CIMZIA": 1.216397609665106, "ENTYVIO": 5.790616425687328, "ESOMEPRAZOLE": 8.281916500075894, "FASLODEX": 4.766539149111688, "ILARIS": 166.32935373573164, "LANTUS": 6.496400305891565, "LEVEMIR": 4.395854657437314, "PLEGRIDY": 6.403381144453388, "SIMPONI": 2.0683739426887, "ZYPADHERA": 9.81296537995781, "null": 1.7054053682347907}
\ No newline at end of file
+{"ANESTHESIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/44.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/44.json
index 2f042f0340b..1ee7344aabd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/44.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/44.json
@@ -1 +1 @@
-{"null": 2.6575345329485165}
\ No newline at end of file
+{"null": 0.7823193218971615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/440.json
index e66587e1f4b..20ba742c9d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/440.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/440.json
@@ -1 +1 @@
-{"ADALIMUMAB": 86.29912269991883, "ANAKINRA": 115.11539136959284}
\ No newline at end of file
+{"EMPAGLIFLOZIN": 182.72392452058568, "MEPOLIZUMAB": 85.09985011209348, "null": 0.6394687952639345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4400.json
index da63e7f9920..e346e9fd882 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4400.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4400.json
@@ -1 +1 @@
-{"null": 4.831281054603175}
\ No newline at end of file
+{"null": 1.7686867308074297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4401.json
index 2769c76836f..127728d5b2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4401.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4401.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.4163040735604557, "APIDRA": 2.073989742540092, "BETAFERON": 3.429145212862429, "BYDUREON": 1.0394545359914715, "COMIRNATY": 3.863586254258995, "COVID19": 2.678747897529838, "ENOXAPARIN": 3.352210618876561, "FASLODEX": 2.8064359679209283, "FORSTEO": 7.84501235718108, "INHIXA": 21.13499359018867, "MEPOLIZUMAB": 1.3573005061568184, "MMRVAXPRO": 1.0866868693808045, "MOVYMIA": 26.99942879771171, "NUTROPINAQ": 67.45453114642442, "PLEGRIDY": 4.671569357451118, "ROACTEMRA": 1.2143501897132392, "SAXENDA": 2.968113775830008, "SPIKEVAX": 4.845505468415294, "TRULICITY": 3.0528603582424934}
\ No newline at end of file
+{"null": 0.5137590138209702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4402.json
index 0259d402d53..fecaa85fe6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4402.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4402.json
@@ -1 +1 @@
-{"ABASAGLAR": 19.351303492751885, "ACLASTA": 14.555397313196542, "AIMOVIG": 10.126202711468084, "APIDRA": 9.32127309417551, "ARANESP": 3.259871913207012, "BENLYSTA": 5.388953773604058, "BETAFERON": 7.617306709067428, "BYDUREON": 82.074174863281, "BYETTA": 5.426434187367427, "CIMZIA": 2.11013919827168, "CLOPIDOGREL": 1.5589717079671743, "COSENTYX": 4.676857768114068, "ENOXAPARIN": 9.029096740130116, "EVISTA": 11.61833532103239, "EYLEA": 4.887088088928733, "FASENRA": 3.484462650716836, "FASLODEX": 2.969183728394444, "FORSTEO": 15.54348744820253, "HIZENTRA": 1.5110880426423037, "HUMALOG": 5.516411457802968, "INHIXA": 25.271097339249344, "INSULIN": 1.3594112474224145, "INTEGRILIN": 13.002030102046518, "KESIMPTA": 5.423620175613192, "LANTUS": 13.88436056819454, "LEVEMIR": 3.2031583462315405, "MEPOLIZUMAB": 1.0914835227655597, "NOVORAPID": 1.1808563782356205, "OMALIZUMAB": 2.417497171054172, "OMNITROPE": 21.70108096101536, "PEGINTRON": 1.290971750839649, "PLAVIX": 1.5883206687892637, "PLEGRIDY": 62.8847273180763, "PROPRANOLOL": 4.057152667527798, "ROACTEMRA": 2.9192062701370878, "SIMPONI": 12.93160701166396, "SKYRIZI": 7.501150440632723, "SOMATROPIN": 9.86754881187074, "STELARA": 1.0951749091673892, "TERROSA": 26.57497786214627, "TOUJEO": 6.315330031783683, "TREMFYA": 10.530192868855435, "TRULICITY": 16.92174243822442, "VICTOZA": 3.296505392407152, "ZYPADHERA": 8.814872713036596}
\ No newline at end of file
+{"RADIOGRAPHIC": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4403.json
index 9ee89c4d4a4..f8ae35a2b41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4403.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4403.json
@@ -1 +1 @@
-{"AFINITOR": 4.325629874317341, "AIMOVIG": 4.933994065692652, "ANAKINRA": 6.726597611740453, "APIDRA": 16.83129912904313, "ENBREL": 2.6018255195136555, "ENTYVIO": 8.129733841708733, "FASLODEX": 4.180749293829014, "FIASP": 18.09600940676135, "FORSTEO": 2.041207973284883, "HUMALOG": 3.574980948566243, "INSULIN": 2.562349935823217, "LANTUS": 1.6278885535024288, "LEVEMIR": 44.45499172669084, "NOVORAPID": 4.817707583247729, "ROACTEMRA": 11.38466984580444, "SAXENDA": 80.45829811070433, "SPIKEVAX": 2.7052043189146726, "TRULICITY": 32.86994266286161, "VICTOZA": 9.236246778390662}
\ No newline at end of file
+{"COMIRNATY": 1.3848419121895346, "VAXZEVRIA": 1.2243224875782968, "null": 0.3514886888110969}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4404.json
index 1ad0469688b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4404.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4404.json
@@ -1 +1 @@
-{"null": 3.442779540174401}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4405.json
index f2ae61cd74e..696224926ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4405.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4405.json
@@ -1 +1 @@
-{"LEVEMIR": 48.60182647065912}
\ No newline at end of file
+{"FENTANYL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4406.json
index d720b372f41..7de4c1a7c8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4406.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4406.json
@@ -1 +1 @@
-{"COMIRNATY": 3.279454823176971, "COVID19": 1.269105468349794, "FASLODEX": 7.182856981274203, "GARDASIL": 1.6310319531892996, "SIMPONI": 2.6203940550544287, "SPIKEVAX": 2.269605912220934, "VAXZEVRIA": 1.9832134184064325}
\ No newline at end of file
+{"ACTRAPID": 8.751528734546733, "ADVATE": 46.93094278082483, "APIDRA": 7.199423882958384, "APIXABAN": 1.0535243263375846, "AUBAGIO": 1.1746005930658716, "BRIDION": 7.006976829676188, "BUDESONIDE": 0.5710754548578297, "BUPIVACAINE": 18.110883139995185, "BYETTA": 1.498202594204081, "COMIRNATY": 0.0569476632747386, "ELIQUIS": 1.3062445285031783, "FAMPYRA": 3.890650974525132, "FIASP": 13.375735541752793, "GARDASIL": 1.532940116482454, "HUMALOG": 3.2149441055627075, "IBRANCE": 0.780340019424154, "INSULIN": 5.33085882368994, "IRBESARTAN": 3.3056372428490173, "JARDIANCE": 0.9753369168362, "KEPPRA": 1.7689454375885818, "LANTUS": 3.7019075759991886, "LATUDA": 2.005714666111704, "LEVEMIR": 3.5811008046237145, "LEVETIRACETAM": 0.9976804766013352, "MEPOLIZUMAB": 2.607913807304313, "MMRVAXPRO": 1.2224094384517716, "NOVORAPID": 11.688452176624503, "OPSUMIT": 1.8498251446170968, "PEGASYS": 0.4750147384750743, "PLAVIX": 1.1308383037919367, "RELVAR": 4.547101710141916, "ROTATEQ": 1.962784754446847, "SHINGRIX": 5.616523038220247, "SOLIRIS": 1.0137969247210454, "SPIKEVAX": 0.287250561914768, "SUBOXONE": 3.0099091121428674, "TOUJEO": 8.135734389530755, "TOVIAZ": 2.127016158423624, "TOZINAMERAN": 1.0441324112690944, "TRELEGY": 8.90091004749655, "TRESIBA": 13.955697291618444, "TRULICITY": 7.982154545373312, "TWINRIX": 6.067105121553268, "VAXZEVRIA": 0.0201871289620142, "VIAGRA": 6.469810207809299, "VICTOZA": 1.8006089080034478, "XELJANZ": 0.3886603665471263, "ZOSTAVAX": 8.199900977860468, "null": 1.8035407221756836}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4407.json
index ad872d0c8dd..90eef23deff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4407.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4407.json
@@ -1 +1 @@
-{"AIMOVIG": 39.54495787148606, "COVID19": 1.2816121824607944, "VAXZEVRIA": 2.347435910299344}
\ No newline at end of file
+{"ENOXAPARIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4408.json
index 2ef0b1e5963..2626bc15737 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4408.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4408.json
@@ -1 +1 @@
-{"APIDRA": 2.7167980293634484, "BETAFERON": 19.87274297123187, "BUVIDAL": 14.16411226087345, "BYDUREON": 8.691160783541305, "COMIRNATY": 1.4186438832209516, "COVID19": 1.228368232102686, "FASLODEX": 7.820753304027004, "GARDASIL": 1.052666772581214, "HIZENTRA": 5.37953995258993, "HUMALOG": 1.909448077347359, "INSULIN": 3.4630584056725904, "LANTUS": 1.828396309545343, "LEVEMIR": 11.30649294693091, "LYUMJEV": 17.396373382693593, "MENVEO": 7.687753755446627, "MMRVAXPRO": 1.6906122983016545, "NIMENRIX": 1.6462692267957588, "NOVORAPID": 3.4819774416232767, "ORENCIA": 10.478637025516663, "PLEGRIDY": 7.866865045266279, "ROACTEMRA": 1.1492671612902234, "SAXENDA": 5.970067784471712, "SHINGRIX": 2.732815818348413, "SPIKEVAX": 8.571263013660637, "TREMFYA": 2.6828618188839246, "TRULICITY": 4.073613948589225, "TWINRIX": 3.901989884982667, "VAXZEVRIA": 1.018430409981162, "VICTOZA": 1.4397580197804265, "ZYPADHERA": 1.6867305340622971}
\ No newline at end of file
+{"VOTRIENT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4409.json
index 1e3dd273ec8..e6778d91726 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4409.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4409.json
@@ -1 +1 @@
-{"APIDRA": 5.354479576643265, "BETAFERON": 69.9395905386055, "BYDUREON": 22.28819826008692, "CIMZIA": 1.7371976666884026, "FASLODEX": 9.30952730204975, "HIZENTRA": 11.669536280759608, "HUMALOG": 2.6274436113433217, "LANTUS": 3.261148882479572, "PEGASYS": 3.627809809232158, "PEGINTRON": 6.618334975687935, "null": 1.1587899823711572}
\ No newline at end of file
+{"MELPHALAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/441.json
index 1bb64e1865f..4c076974747 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/441.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/441.json
@@ -1 +1 @@
-{"ARAVA": 15.334795269142532}
\ No newline at end of file
+{"null": 3.440318901667623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4410.json
index 9a5189b370f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4410.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4410.json
@@ -1 +1 @@
-{"ACLASTA": 1.5255942283996875, "BETAFERON": 3.108856076207028, "BUVIDAL": 2.3447024669156016, "COMIRNATY": 3.541512045035942, "COVID19": 3.53590516428511, "FIASP": 1.158810182990171, "MMRVAXPRO": 4.126982063857407, "NIMENRIX": 8.70069368119491, "SPIKEVAX": 10.07762846519463}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4411.json
index f3a3296519f..778e519e54e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4411.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4411.json
@@ -1 +1 @@
-{"APIDRA": 12.294740008179598, "BYDUREON": 33.231796607408334, "FASLODEX": 23.0214824752152, "HUMALOG": 5.367992592604903, "LANTUS": 11.465726945683135, "PLEGRIDY": 53.63190773408921, "TRULICITY": 23.00373230491704, "null": 1.2691757954431109}
\ No newline at end of file
+{"CUBICIN": 43.56351430047237, "FENTANYL": 29.327294242239745, "null": 1.2648879175053822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4412.json
index 318053c67f4..b31ca3a0d9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4412.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4412.json
@@ -1 +1 @@
-{"AIMOVIG": 7.575003261939572, "CIMZIA": 3.786251237328044, "FASLODEX": 8.658463093599607, "FIASP": 40.746058343897126, "GARDASIL": 3.071041323548865, "HIZENTRA": 12.623836290080211, "HUMALOG": 2.584536848938182, "LANTUS": 2.877473754646858, "PLEGRIDY": 25.9610552877054, "SAXENDA": 48.73667426736208, "TRULICITY": 13.961167707962874}
\ No newline at end of file
+{"CLOPIDOGREL": 26.75802225539789, "ELIQUIS": 13.023468649520046, "ENOXAPARIN": 44.09704635554694, "FENTANYL": 3.01499082700641, "PLAVIX": 14.32327272171473, "null": 2.0103411658825308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4413.json
index e13ea5ec68c..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4413.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4413.json
@@ -1 +1 @@
-{"null": 7.136878144484689}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4414.json
index 83c198f5965..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4414.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4414.json
@@ -1 +1 @@
-{"COVID19": 2.198008132860444, "SPIKEVAX": 1.7972279778011837}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4415.json
index 42494249169..14f8d5fa251 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4415.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4415.json
@@ -1 +1 @@
-{"null": 2.7801871827442293}
\ No newline at end of file
+{"AUBAGIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4416.json
index b4b4207ba85..0f20649561a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4416.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4416.json
@@ -1 +1 @@
-{"COMIRNATY": 4.773549034603106, "SPIKEVAX": 2.9882110432863307, "VAXZEVRIA": 3.302547569540732}
\ No newline at end of file
+{"PACLITAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4417.json
index 01d05882a2b..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4417.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4417.json
@@ -1 +1 @@
-{"COMIRNATY": 2.0185577449333847, "COVID19": 2.3221512869589893, "SPIKEVAX": 1.9719544807464664, "VAXZEVRIA": 2.7323034413300613}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4418.json
index ae7bcd4b2c3..b5fffaf4307 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4418.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4418.json
@@ -1 +1 @@
-{"COVID19": 3.2573999382393377, "SPIKEVAX": 1.413920090815857, "VAXZEVRIA": 1.3718230536140967, "null": 1.1982190929801075}
\ No newline at end of file
+{"ENTYVIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4419.json
index a265432ad3c..6cc2bb4d123 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4419.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4419.json
@@ -1 +1 @@
-{"null": 4.773427223895921}
\ No newline at end of file
+{"JAKAVI": 67.63130154274111, "REBLOZYL": 2219.0164051742645, "null": 0.4729342430326713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/442.json
index ebc3fe3902b..b0adb85b42d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/442.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/442.json
@@ -1 +1 @@
-{"ANORO": 1.84968819501982, "APIDRA": 1.4997046032219492, "ATRIPLA": 20.673477754037624, "AUBAGIO": 1.6867392271443964, "AVANDIA": 1.2173177296147226, "BYDUREON": 1.664779771410675, "BYETTA": 1.3077000827354577, "EVISTA": 5.463992749685228, "EXFORGE": 1.0211934922599657, "FAMPYRA": 5.198550466919186, "FORSTEO": 2.988355680426995, "HIZENTRA": 1.4413965248984169, "HUMALOG": 3.3332642325989776, "IBRANCE": 1.6272052646590238, "IRON": 6.864011722776922, "KALETRA": 1.0791875169527283, "LANTUS": 3.0201547846403467, "LEFLUNOMIDE": 4.64320478763225, "LEVEMIR": 1.312796239627788, "LYRICA": 2.265033883015292, "OCRELIZUMAB": 11.93051982137408, "OMALIZUMAB": 1.0492634500230391, "PREGABALIN": 1.6078291580444934, "REVATIO": 2.846316494998712, "RINVOQ": 2.066262241425713, "SAXENDA": 1.400001757574803, "SIMPONI": 1.941084036452165, "SPINRAZA": 2.7369788983894483, "STELARA": 1.169054368215391, "STRIBILD": 16.419407186686197, "SUBOXONE": 3.0494537728361064, "TOVIAZ": 1.5702618327011804, "TRELEGY": 1.197591539116198, "TRUVADA": 15.434480687157956, "VIAGRA": 2.8047186156148074, "VIREAD": 8.570846317041044, "XELJANZ": 3.9407655637284713, "XOLAIR": 1.473391556077981, "ZOSTAVAX": 1.1284998929425063}
\ No newline at end of file
+{"PRIVIGEN": 272.8072824683236, "null": 1.213142761852697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4420.json
index 42b96abb28a..1c32108eaca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4420.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4420.json
@@ -1 +1 @@
-{"COMIRNATY": 7.570753144330452, "SPIKEVAX": 3.386726191867222}
\ No newline at end of file
+{"CICLOSPORIN": 13.885188966830086, "null": 0.8005754458928745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4421.json
index 6788d168357..d7d94f67cd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4421.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4421.json
@@ -1 +1 @@
-{"SPIKEVAX": 2.2311628493172946}
\ No newline at end of file
+{"COMIRNATY": 0.5431412567292944, "null": 0.7773028040731379}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4422.json
index beb568c7a4e..751543a20d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4422.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4422.json
@@ -1 +1 @@
-{"ABASAGLAR": 10.178046675029629, "AFINITOR": 2.7466937902185693, "AIMOVIG": 1.6340231625847366, "APIDRA": 2.4272433607256487, "BETAFERON": 14.03604619650286, "BEXSERO": 7.726266586601151, "BUVIDAL": 132.48201321544602, "BYDUREON": 80.01332610649331, "BYETTA": 1.9940795472936017, "COSENTYX": 3.207441747723927, "COVID19": 4.811952951021213, "EVENITY": 4.571729353193205, "FASLODEX": 19.188252903653304, "FIASP": 9.35304123785286, "FORSTEO": 2.266437151881663, "HIZENTRA": 5.087958634138352, "HUMALOG": 5.3933389154404345, "INSULIN": 1.5573219557933973, "LANTUS": 4.138643944136933, "LEVEMIR": 23.58107779973397, "LUTETIUM": 24.14235755997068, "LYUMJEV": 43.04204303733281, "NIMENRIX": 1.8154164121604237, "NOVORAPID": 3.907895879742018, "PLEGRIDY": 3.726454143235781, "SAXENDA": 11.623357067156014, "SIMPONI": 1.2500603977095897, "TOUJEO": 4.058109619468821, "TREMFYA": 2.5563633257861187, "TRULICITY": 16.36851395854585, "VICTOZA": 3.465013803787788, "XOLAIR": 1.6334566085765494, "ZOSTAVAX": 1.624030484511537, "ZYPADHERA": 3.757335327248045}
\ No newline at end of file
+{"null": 0.4491125594149601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4423.json
index 8112959182a..8fa3b91c524 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4423.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4423.json
@@ -1 +1 @@
-{"COMIRNATY": 4.000425876547105, "SPIKEVAX": 4.564479292133886, "VAXZEVRIA": 4.166269309341488}
\ No newline at end of file
+{"ABILIFY": 16.595862484815655, "AGOMELATINE": 34.82692629723762, "AIMOVIG": 9.768929181940658, "ARIPIPRAZOLE": 49.69918808221738, "BRINTELLIX": 1.461441336678307, "BUPRENORPHINE": 0.925117911002286, "CARIPRAZINE": 39.464137526062856, "COMIRNATY": 0.0179611888847291, "CORTICOSTEROIDS": 17.00860541866718, "CYMBALTA": 1.7124872994153817, "DULOXETINE": 1.7515040122459309, "EBIXA": 9.32988702400309, "ERENUMAB": 60.99521700526485, "FENTANYL": 0.833933676961401, "INVEGA": 30.399788263878825, "IRBESARTAN": 2.114318540252831, "KEPPRA": 1.1487259034085546, "LATUDA": 16.212708043419088, "LEVETIRACETAM": 1.7376252801152938, "LEVODOPA": 4.9289084823178575, "LEVOFLOXACIN": 0.5074908832578012, "LOXAPINE": 17.46911214507023, "LURASIDONE": 11.732415876037631, "LYRICA": 1.3545856895529755, "OLANZAPINE": 31.58777590685633, "PALIPERIDONE": 34.98160331614806, "PEGASYS": 0.2528215712463116, "PEGINTRON": 0.2727400596284472, "PREGABALIN": 1.407421138487824, "REAGILA": 27.447262021474742, "RISPERIDONE": 35.78011921299647, "SYCREST": 65.71557977440469, "VAXZEVRIA": 0.0290037891829776, "VIMPAT": 1.2893505419592115, "XEPLION": 53.19828458071488, "ZYPADHERA": 24.678070147681662, "ZYPREXA": 17.223853266768288, "null": 2.568556139377313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4424.json
index c6ad3f39342..4abdd7ea39c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4424.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4424.json
@@ -1 +1 @@
-{"COMIRNATY": 6.078971809531408, "COVID19": 1.1598976983216216, "SPIKEVAX": 2.8505726202188577, "VAXZEVRIA": 2.011286529984275}
\ No newline at end of file
+{"PAZOPANIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4425.json
index 30cbeadc655..82d8a7731c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4425.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4425.json
@@ -1 +1 @@
-{"BETAFERON": 242.46496516396616, "BYDUREON": 5.6828267251085975, "ENOXAPARIN": 14.44022766831718, "FASLODEX": 26.26696720560008, "FULVESTRANT": 8.739781669322744, "HIZENTRA": 13.817646409161682, "LANTUS": 1.7418341165508833, "PEGINTERFERON": 6.651264214852836, "PEGINTRON": 41.4015605968823, "PLEGRIDY": 8.09404981101053, "REBETOL": 24.38215089986352, "SUBOXONE": 3.434426479284284, "null": 2.140831190131402}
\ No newline at end of file
+{"null": 1.2754798698693273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4426.json
index 9b8cdd727f4..d63813e82f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4426.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4426.json
@@ -1 +1 @@
-{"null": 1.1050395043329635}
\ No newline at end of file
+{"TEMOZOLOMIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4427.json
index 365ddec55a8..af95a5bbe97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4427.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4427.json
@@ -1 +1 @@
-{"APIDRA": 7.265806005051203, "BETAFERON": 16.28219088088887, "BUVIDAL": 101.10611988042058, "BYDUREON": 388.8071772502229, "CABOTEGRAVIR": 86.06832264683266, "ENOXAPARIN": 6.432119677991995, "FASLODEX": 20.34957456649347, "FORSTEO": 2.0263454077594787, "GARDASIL": 1.2071872440217442, "HIZENTRA": 7.399300738917742, "HUMALOG": 1.3880963066287724, "INSULIN": 6.901422013170029, "LANTUS": 6.113263817932968, "LEVEMIR": 12.987068176609336, "TRULICITY": 6.3388732274982456}
\ No newline at end of file
+{"AIMOVIG": 1.0864919138529547, "BRINTELLIX": 0.8890073277119499, "CHAMPIX": 0.2875516801777351, "COMIRNATY": 2.6254077633114385, "CYMBALTA": 0.2486404410157972, "ELIQUIS": 0.4811229476543507, "ENTRESTO": 1.5099622174027467, "EXFORGE": 1.593036520777595, "FENTANYL": 0.9778440366066742, "FORSTEO": 1.4286716592497912, "GARDASIL": 0.2413073176550713, "HUMALOG": 0.2524410317727611, "ICLUSIG": 1.6455544643079365, "IRBESARTAN": 6.926790779835981, "LANTUS": 0.233175396321183, "MIDAZOLAM": 2.382716820685609, "MODERNA": 0.6536767182031267, "MULTAQ": 6.433265702433401, "OLANZAPINE": 0.3415793713488582, "OXYBUTYNIN": 4.195771481550629, "PEGASYS": 0.2190334912114808, "PEGINTRON": 0.5067602994228382, "RASILEZ": 6.111300369107672, "SHINGRIX": 0.4934283913283168, "SPIKEVAX": 1.7933424118619918, "TASIGNA": 1.2123659616675708, "TOZINAMERAN": 1.6171854847636986, "VAXZEVRIA": 0.8642772951291774, "VFEND": 1.0182986179561964, "XELJANZ": 0.3042217446914354, "ZYPREXA": 0.8740619576064729, "null": 0.9671855595389972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4428.json
index 3f2c46a02c4..2be82b6554c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4428.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4428.json
@@ -1 +1 @@
-{"APIDRA": 3.33371711902046, "BETAFERON": 5.978895877557384, "COMIRNATY": 2.798774516405392, "ENTYVIO": 2.949061574053319, "FASLODEX": 1.481893949794787, "HIZENTRA": 2.163407103728765, "LEVEMIR": 4.433314725857291, "MENVEO": 17.455522973032824, "MMRVAXPRO": 2.453367024156379, "NIMENRIX": 4.468518269402137, "PLEGRIDY": 5.2417536033569805, "ROACTEMRA": 4.684748817671361, "ROTARIX": 67.93583811313353, "SAXENDA": 2.1014673620694597, "SHINGRIX": 1.444158699733129, "SOMAVERT": 48.46273341790186, "SPIKEVAX": 2.069742848874513, "TREMFYA": 4.774647588402623, "TRULICITY": 5.716416796659002, "VAXZEVRIA": 1.0869906837623131, "XOLAIR": 2.788245982201012}
\ No newline at end of file
+{"BONVIVA": 16.3326894785501, "CAELYX": 24.702306206251336, "COMIRNATY": 0.022213151705587, "DARZALEX": 19.75494220537353, "DEXDOR": 90.8609320988482, "ENTRESTO": 1.6155217084271318, "FENTANYL": 3.627203830745712, "JEVTANA": 22.20810187434947, "KEPPRA": 1.402307965805058, "KYPROLIS": 23.3146038766316, "NAGLAZYME": 11.603848051508804, "PRIVIGEN": 12.782158107584708, "REMDESIVIR": 32.45603113180072, "TORISEL": 12.820160625412464, "TRODELVY": 14.92973406017034, "YONDELIS": 219.13372806767552, "null": 4.220133505172231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4429.json
index 134fed55163..ab27efa0980 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4429.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4429.json
@@ -1 +1 @@
-{"ABASAGLAR": 5.027834730728956, "AIMOVIG": 1.02959901418648, "APIDRA": 1.0127224788577884, "BETAFERON": 3.4249191496727875, "BUVIDAL": 5.816680215162662, "BYDUREON": 3.123125430483474, "CABOTEGRAVIR": 10.967564639171965, "CERVARIX": 1.5273500572546943, "COMIRNATY": 4.142683309206558, "COVID19": 2.4085417306501555, "DULAGLUTIDE": 1.0084045059258853, "EVENITY": 1.4920372702467664, "FASLODEX": 2.018119328083768, "FIASP": 1.8668097150635836, "HEMLIBRA": 1.43787621108809, "HYQVIA": 1.3689266138089915, "IDACIO": 7.634727393614623, "INHIXA": 7.797921113324845, "JCOVDEN": 3.707249111909928, "LANTUS": 1.173960275061933, "LEVEMIR": 1.018613388673212, "LYUMJEV": 15.211592454047496, "MENVEO": 1.668911410201258, "MMRVAXPRO": 1.2519763114420182, "MOVYMIA": 1.3260055483174868, "NIMENRIX": 3.148522282930843, "NUTROPINAQ": 7.479922708016208, "OCTREOTIDE": 1.1830129119515536, "OMNITROPE": 4.978477429703687, "PLEGRIDY": 2.637598636364408, "REKAMBYS": 13.865626365221038, "ROTARIX": 1.964141258526728, "SHINGRIX": 2.418107481043463, "SOMATROPIN": 1.0734033311194622, "SOMAVERT": 2.163059552454616, "SPIKEVAX": 5.90173206900908, "TALTZ": 2.943991133840602, "TOUJEO": 1.2973020446667396, "TRULICITY": 2.85446627575715, "TWINRIX": 1.2303576579895288, "VAXZEVRIA": 2.215580468971463}
\ No newline at end of file
+{"BRILIQUE": 44.172588191445485, "CLOPIDOGREL": 7.325723156632959, "COMIRNATY": 0.5838715354005101, "VAXZEVRIA": 0.5302443956688383, "null": 0.995854327618474}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/443.json
index 2d160fe39ef..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/443.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/443.json
@@ -1 +1 @@
-{"ARAVA": 2.4790450462881704, "CIMZIA": 4.935553140089498, "JANUMET": 17.871831434914583}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4430.json
index 8872e4dccb7..a4a604324ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4430.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4430.json
@@ -1 +1 @@
-{"null": 4.995997872223249}
\ No newline at end of file
+{"SOLIRIS": 1918.0550230097808}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4431.json
index 8f005b8432d..a6a125fcdb2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4431.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4431.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.0090245638383015}
\ No newline at end of file
+{"ARAVA": 4.122586043687391, "COMIRNATY": 0.2138706662861554, "CONTRAST": 410.1498784139749, "OPTIMARK": 393.88532200964505, "null": 0.6981872615138784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4432.json
index 51fa62c2c9c..bac936ff398 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4432.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4432.json
@@ -1 +1 @@
-{"COMIRNATY": 3.068697257100028, "COVID19": 1.3167347664026934, "FORSTEO": 3.4597242153714096, "GARDASIL": 2.2674519405757576, "SHINGRIX": 3.400698010385687, "SPIKEVAX": 2.5540565169392084, "VAXZEVRIA": 1.2725514140485603}
\ No newline at end of file
+{"COMIRNATY": 0.099110265745184, "ELIQUIS": 1.3078243898685613, "FORXIGA": 7.401636042265064, "JARDIANCE": 10.069868463699937, "LANTUS": 2.736652941003308, "NEXAVAR": 2.910304177394224, "PEGASYS": 1.9737074722451704, "ROACTEMRA": 18.15597222859984, "null": 1.1225936013332731}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4433.json
index 0aa87303614..211ef9ee626 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4433.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4433.json
@@ -1 +1 @@
-{"null": 12.442638870519998}
\ No newline at end of file
+{"null": 1.1813139140775986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4434.json
index 852de993763..532ff062769 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4434.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4434.json
@@ -1 +1 @@
-{"TRULICITY": 30.059265813213}
\ No newline at end of file
+{"null": 0.8893525261632298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4435.json
index c94cb008da8..a4dfc389c14 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4435.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4435.json
@@ -1 +1 @@
-{"ABASAGLAR": 4.789358893265909, "AIMOVIG": 2.231691375073261, "APIDRA": 1.8016435055530355, "BUVIDAL": 16.98901595649729, "BYDUREON": 9.29306652733537, "COMIRNATY": 1.896199588079435, "COVID19": 1.6128122665985791, "DULAGLUTIDE": 4.156081596373442, "ENBREL": 1.3594780403525617, "ENTYVIO": 2.283538979808633, "EVENITY": 1.4775364295635702, "FASLODEX": 2.5175854666802238, "FIASP": 3.2241233158346687, "FORSTEO": 1.254838885663739, "HIZENTRA": 4.280869680900624, "INHIXA": 9.18505094045733, "INSULATARD": 5.926416077490024, "INSULIN": 1.6164406131510354, "KESIMPTA": 1.517069498119927, "LEVEMIR": 8.740300564584297, "LYUMJEV": 13.984652241906804, "MENVEO": 2.2141612325441598, "MMRVAXPRO": 1.147226296622738, "NIMENRIX": 7.378142051352186, "NOVOMIX": 13.209800082830222, "NOVORAPID": 1.699871275733238, "PLEGRIDY": 11.843297362292672, "PREVENAR": 1.198469744286896, "ROACTEMRA": 2.566014453918702, "SAXENDA": 19.901706532493257, "SHINGRIX": 2.199849579983649, "SPIKEVAX": 9.135957619599882, "TOUJEO": 1.862293073839281, "TREMFYA": 2.067079118421328, "TRESIBA": 3.2954319615690504, "TRULICITY": 14.331781003929477, "TWINRIX": 1.8713052705944828, "VICTOZA": 3.7417049951661103, "XOLAIR": 1.6269065509757004}
\ No newline at end of file
+{"COMIRNATY": 0.6420140050164005, "SPIKEVAX": 0.5732058000735103, "TOZINAMERAN": 1.699004564593863, "VAXZEVRIA": 0.8119447360621191, "null": 1.1504603326864948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4436.json
index 22ee5612939..1203d648c63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4436.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4436.json
@@ -1 +1 @@
-{"ABASAGLAR": 7.09270767931323, "AIMOVIG": 6.683290972784993, "BENLYSTA": 1.646710060625174, "BETAFERON": 8.279254956593867, "BUVIDAL": 17.38515844174335, "BYDUREON": 5.837601091861755, "CIMZIA": 2.6908221422303, "COVID19": 1.2955996564427048, "ENBREL": 3.408703104418113, "ENOXAPARIN": 4.27664745271828, "ENTYVIO": 2.772123554064716, "FASENRA": 4.209514037073743, "FASLODEX": 3.835060711551751, "FIASP": 5.846281398249956, "FORSTEO": 2.101336374302681, "HIZENTRA": 4.797894981870561, "HUMALOG": 1.6420936588057755, "INSULATARD": 13.398190512472777, "INSULIN": 1.1747296845348665, "LANTUS": 1.3013123492712504, "LEVEMIR": 10.97844969449756, "MMRVAXPRO": 4.624084386621269, "NIMENRIX": 3.5116178554161763, "NOVORAPID": 3.214744312999425, "NUCALA": 1.2537642509615092, "PEGASYS": 4.488240407203239, "PEGINTERFERON": 1.2784939702911808, "PEGINTRON": 5.529265529774063, "PLEGRIDY": 35.06176745408162, "ROACTEMRA": 8.080737646875523, "SAXENDA": 48.78521392180695, "SHINGRIX": 5.68896327002099, "SPIKEVAX": 2.983290176891367, "TREMFYA": 2.190674353365404, "TRULICITY": 16.084646214496072, "VICTOZA": 12.193248639472198, "XOLAIR": 2.0114252623578666, "ZOSTAVAX": 2.763427012202728}
\ No newline at end of file
+{"COMIRNATY": 0.1866755629528303, "SPIKEVAX": 1.0415238519620065, "SUTENT": 5.289142103421447, "VAXZEVRIA": 0.3072220962375579, "null": 0.9003581577378438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4437.json
index 431be70949f..a779db4d9bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4437.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4437.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.407472071824382, "ACTRAPID": 1.0426736673434664, "ADALIMUMAB": 1.555869982945986, "AIMOVIG": 1.5880916428665706, "ANAKINRA": 2.663315037963486, "APIDRA": 1.3632673611230457, "BETAFERON": 11.620657051754536, "BEXSERO": 1.158554722244887, "BONVIVA": 1.675489619862352, "BUVIDAL": 3.042190760083189, "BYDUREON": 1.924165312528173, "CABOTEGRAVIR": 4.021881858591831, "CIMZIA": 1.8989760867971384, "COMIRNATY": 2.805189104071823, "COSENTYX": 1.151188468464702, "ENBREL": 2.529148801741128, "ENTYVIO": 2.7560688709137806, "EVENITY": 1.1634485995246042, "FASENRA": 1.5329364599267663, "FASLODEX": 1.2917566770921565, "FIASP": 1.144320251114323, "HEMLIBRA": 2.481843720567228, "HIZENTRA": 1.3962198204847998, "IDACIO": 4.517619077376616, "INFANRIX": 1.840121132372016, "INSULATARD": 3.773379391242388, "KESIMPTA": 1.926540528830172, "LEVEMIR": 4.114331596347724, "LYUMJEV": 6.199753713454663, "MENVEO": 2.547688211026684, "MIXTARD": 5.044178056233551, "NIMENRIX": 1.877127864737281, "PEGASYS": 1.3720175115462756, "PEGINTRON": 2.814292652181166, "PLEGRIDY": 16.94808451489503, "REBETOL": 1.2640422352805312, "REKAMBYS": 6.399790897747688, "ROACTEMRA": 4.807364579615544, "SAXENDA": 2.829861355947425, "SHINGRIX": 1.1498720985592694, "SPIKEVAX": 4.064794001536034, "TREMFYA": 3.0772059698816028, "TRULICITY": 3.0564400439672155, "TWINRIX": 1.2399572719286718, "VAXZEVRIA": 4.563089401631374, "VICTOZA": 1.61434023632343, "XOLAIR": 2.1324345902204658}
\ No newline at end of file
+{"null": 2.147225067505238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4438.json
index 07d35e4adcb..6af29fc32ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4438.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4438.json
@@ -1 +1 @@
-{"BYDUREON": 56.7557451221051}
\ No newline at end of file
+{"ARAVA": 0.545088199890385, "COMIRNATY": 0.3269616527901055, "CYMBALTA": 1.489178121399616, "ELIQUIS": 3.0743215823661934, "LYRICA": 10.758311890535872, "OMALIZUMAB": 5.905180235766008, "SPIKEVAX": 0.3660606103680991, "SUTENT": 1.2945889180471597, "TOZINAMERAN": 1.9304181683161088, "VAXZEVRIA": 0.7039711256657413, "null": 1.0324719844626475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4439.json
index 904bed41e63..83f7f2c1157 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4439.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4439.json
@@ -1 +1 @@
-{"BYDUREON": 40.95262671786841, "HUMALOG": 13.947291957017791, "LANTUS": 7.296481033139446, "null": 1.3604723609760694}
\ No newline at end of file
+{"null": 2.3857612088043374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/444.json
index 84752f9434c..37cc01873a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/444.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/444.json
@@ -1 +1 @@
-{"AMGEVITA": 86.78172966017884, "ANAKINRA": 2.260988298120851, "ARAVA": 2.2825634434356075, "ATEZOLIZUMAB": 32.795236475489894, "CELECOXIB": 4.722041006679708, "CIMZIA": 77.07517434305815, "COSENTYX": 42.79634456688247, "EMPAGLIFLOZIN": 5.361573722202103, "ENBREL": 7.850933516294374, "ENTYVIO": 4.701029525624019, "ETANERCEPT": 17.687758158197074, "HUMIRA": 11.47384731780143, "METHOTREXATE": 1.8812335326096388, "RINVOQ": 2.816111474897571, "SIMPONI": 53.92058959189155, "STELARA": 3.1199058524417875, "TREMFYA": 2.7764047075032097, "XELJANZ": 2.155962418203152}
\ No newline at end of file
+{"DEXAMETHASONE": 64.21372087421484, "SUFENTANIL": 186.1501833360041, "null": 3.966104153958266}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4440.json
index 0c6c8401c30..f86dabc4e96 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4440.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4440.json
@@ -1 +1 @@
-{"AIMOVIG": 1.1650107137453287, "BETAFERON": 1.4044462138712932, "BEXSERO": 1.075968370055245, "BONVIVA": 1.1106779892748746, "BUVIDAL": 8.387197302836425, "BYDUREON": 1.5270522182616562, "CABOTEGRAVIR": 2.195539606297466, "CERVARIX": 2.458172360727372, "COMIRNATY": 3.311375266317887, "COVID19": 2.0514718606525166, "EVENITY": 2.986074547492431, "HIZENTRA": 2.43063618930381, "HYQVIA": 1.7052002981992471, "INFANRIX": 1.4217000954586525, "JCOVDEN": 2.2167763259379547, "KESIMPTA": 1.0468172590494114, "LEVEMIR": 2.0640411473575746, "LYUMJEV": 1.6961561025036835, "MENQUADFI": 6.5697580854623325, "MENVEO": 1.6460085445460495, "MEPOLIZUMAB": 1.0338132205943174, "MIXTARD": 1.1304328600054914, "MMRVAXPRO": 2.586641463528682, "NIMENRIX": 7.183105379387489, "OCTREOTIDE": 1.9628528606252589, "PLEGRIDY": 1.9413285771363349, "REKAMBYS": 3.4304522456163618, "SAXENDA": 2.678936252607946, "SHINGRIX": 3.569833087863631, "SPIKEVAX": 9.323067276692438, "TRULICITY": 1.7143887338002877, "TWINRIX": 1.9806631401748132, "VAXZEVRIA": 1.0914610263728963}
\ No newline at end of file
+{"AFINITOR": 1.3913165952779027, "COMIRNATY": 0.3241424208095419, "COSENTYX": 2.449319493063262, "EYLEA": 13.288184770012515, "HUMALOG": 1.1100320508896766, "IBRANCE": 1.161898651834399, "LANTUS": 0.5886458873041195, "MMRVAXPRO": 2.7405085538727927, "NEVANAC": 123.80653717525392, "OMALIZUMAB": 7.522479962561048, "PEGASYS": 1.827102613954753, "SPIKEVAX": 0.3296858263745979, "SUTENT": 1.3201474990064357, "TOZINAMERAN": 0.9556542924370076, "VAXZEVRIA": 0.1635820535700823, "XELJANZ": 1.852103951007346, "ZOSTAVAX": 2.142237344686216, "null": 1.8594082155849647}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4441.json
index 2a1392df024..983cd04cb59 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4441.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4441.json
@@ -1 +1 @@
-{"null": 5.54755357753633}
\ No newline at end of file
+{"ABACAVIR": 0.7842868055875194, "ABATACEPT": 0.7611253777714161, "AIMOVIG": 0.390768446387399, "ANORO": 3.447257683678464, "APIDRA": 2.022267112237173, "ARAVA": 1.1820607195578443, "AUBAGIO": 1.158374772421625, "AVANDAMET": 1.567732828958265, "AVANDIA": 1.444272667426462, "AZATHIOPRINE": 0.9507407302723752, "BENLYSTA": 0.9360364010471042, "BOSULIF": 1.5247744650969517, "BRAFTOVI": 4.897555542825799, "BUDESONIDE": 0.5499328141565157, "BYDUREON": 0.8329971774977775, "BYETTA": 0.5950929590043343, "CELECOXIB": 1.941833926438282, "CELLCEPT": 0.5281829905743664, "CHAMPIX": 0.659490969288592, "CICLOSPORIN": 0.2984180592077828, "CIMZIA": 1.0414210141348057, "CLOPIDOGREL": 0.3440075051703454, "COMIRNATY": 0.3547655478038226, "COSENTYX": 0.7355062911328626, "CYMBALTA": 1.1780138002827387, "DEXAMETHASONE": 1.3798231977993225, "DUPIXENT": 4.414523749454035, "ELIQUIS": 2.4851529868411117, "ENBREL": 2.8678700039787985, "ENTRESTO": 0.6108979197421851, "ESBRIET": 0.7476172154649698, "EVISTA": 1.5007287516507428, "EXFORGE": 1.6063358271470696, "EXJADE": 1.5174370304223226, "EYLEA": 9.146482332862528, "FASENRA": 2.430727451544555, "FENTANYL": 0.7052968188327737, "FORSTEO": 1.0008795775082318, "GARDASIL": 1.0497610806799158, "HUMALOG": 5.448398075441043, "HUMIRA": 2.597993664896101, "IBRANCE": 1.883292807868785, "IBUPROFEN": 1.0380216611888615, "INLYTA": 1.481120414208157, "INSULIN": 1.6662978596857525, "JANUMET": 0.7356218566490135, "JANUVIA": 1.0602309788384303, "KEPPRA": 0.7359465197062437, "KEYTRUDA": 0.3722691358517938, "LANTUS": 7.314088836733189, "LEMTRADA": 0.9607172339984588, "LEVEMIR": 1.829973244819018, "LEVOFLOXACIN": 0.429275413834958, "LYRICA": 1.4141169517443086, "MEKINIST": 2.169109793312289, "MEPOLIZUMAB": 0.6936615995548839, "METHOTREXATE": 0.3878023357175507, "NORVIR": 2.056079777300712, "NUCALA": 0.4054306923303937, "OMALIZUMAB": 1.320252870803126, "PEGASYS": 1.0377379763768049, "PEGINTRON": 1.410096193364868, "PLAVIX": 0.4862758366056616, "REVATIO": 2.9090227193725964, "RINVOQ": 1.6082260074646764, "RITUXIMAB": 1.5422170730541886, "SHINGRIX": 0.5862879067811851, "SIMPONI": 1.1047346540878435, "SPIKEVAX": 0.1949220430648752, "SPRYCEL": 0.8407204259480194, "STELARA": 0.3506659556975127, "SUBOXONE": 0.72611419598144, "SUTENT": 0.9189405705000104, "TAGRISSO": 1.4031172844899693, "TOUJEO": 2.5231741222247206, "TOVIAZ": 3.862410515655502, "TOZINAMERAN": 1.271896318511001, "TRELEGY": 1.57750953293469, "TRULICITY": 1.1176445199604526, "VAXZEVRIA": 0.2101129786020282, "VFEND": 1.5807457858995733, "VIAGRA": 4.273283090443046, "VICTOZA": 0.7689667989323722, "VORICONAZOLE": 3.290277163194757, "XALKORI": 1.8772777277856096, "XELJANZ": 2.0842851381664573, "XOLAIR": 1.129096824945211, "XTANDI": 0.437459927617005, "ZOSTAVAX": 2.5531700045387558, "ZYPREXA": 0.6689994227755316, "null": 1.4229935539724363}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4442.json
index 72ae0b804ba..5480d88944a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4442.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4442.json
@@ -1 +1 @@
-{"ACTRAPID": 72.07452070892896, "BETAFERON": 150.39654939070428, "FASLODEX": 62.73676458803966, "HIZENTRA": 19.73151133587743, "LAMIVUDINE": 37.96669611181628, "LANTUS": 2.685024518371889, "PEGASYS": 2.5739437988065528, "PEGINTRON": 54.40757624041827}
\ No newline at end of file
+{"null": 0.5433282862058165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4443.json
index a58b4c79f03..5744a39e17b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4443.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4443.json
@@ -1 +1 @@
-{"ABASAGLAR": 8.595450092692062, "AIMOVIG": 9.125992622190436, "APIDRA": 4.612655303432383, "BYDUREON": 15.17340043887058, "BYETTA": 1.8848471809399845, "CIMZIA": 3.251129943625961, "COSENTYX": 1.2469217166708524, "ENBREL": 3.2057358762172123, "ENTYVIO": 5.094081222385403, "FASLODEX": 2.048212424913828, "FENTANYL": 1.1791701823667866, "FORSTEO": 2.5996134981906494, "HIZENTRA": 7.536768900084261, "HUMALOG": 4.409697891694683, "INSULIN": 6.974209573713489, "LANTUS": 1.7720066518220958, "LEVEMIR": 27.167168800624683, "MIDAZOLAM": 4.449521590604828, "MMRVAXPRO": 1.440742257413834, "NOVORAPID": 3.667253414712229, "NUCALA": 1.9099955077886217, "PLEGRIDY": 11.932806139661595, "ROACTEMRA": 5.934573817635965, "SAXENDA": 45.60513135873133, "SHINGRIX": 2.1352605955515496, "SPIKEVAX": 1.555169339800456, "TREMFYA": 8.704523241469824, "TRULICITY": 10.22369095720672, "VICTOZA": 11.09685250007087, "XOLAIR": 5.925211167070972}
\ No newline at end of file
+{"COMIRNATY": 2.272801916927486, "ELIQUIS": 4.415250938136524, "SPIKEVAX": 0.7015891776475704, "VAXZEVRIA": 2.6579099228025327, "null": 0.181737787277515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4444.json
index e121347d831..d13d6b410e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4444.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4444.json
@@ -1 +1 @@
-{"AIMOVIG": 3.04523206805003, "BYDUREON": 7.670003761909322, "CIMZIA": 2.1429518965813568, "ENBREL": 2.6492935831254703, "FASLODEX": 5.03903485224662, "LANTUS": 1.7682015771614372, "MMRVAXPRO": 11.23907686264527, "PEGINTRON": 2.89159128554541, "SAXENDA": 9.071992541974394, "SHINGRIX": 16.17702748093092, "TRULICITY": 9.488777453942202, "ZOSTAVAX": 4.253103075300228, "null": 1.222024707395569}
\ No newline at end of file
+{"APIDRA": 4.1372166223921925, "ARAVA": 0.3108592481665681, "AVANDIA": 0.3980974019596229, "AVASTIN": 1.3971901965368851, "BEOVU": 9.11409884699867, "BRILIQUE": 6.0432021037232495, "BRINTELLIX": 0.6894699943515828, "BYDUREON": 0.7040990468755483, "BYETTA": 0.589661187310525, "CHAMPIX": 0.4262399642078908, "CLOPIDOGREL": 2.7548409085949053, "COMIRNATY": 0.5131795127134471, "CYMBALTA": 0.2826482595335944, "ELIQUIS": 11.308052420645025, "ESOMEPRAZOLE": 2.7705090300515733, "EVISTA": 2.107932962428776, "EXFORGE": 1.6513093768592926, "EYLEA": 32.40685679091044, "FORSTEO": 0.804289770740857, "HUMALOG": 17.46089326017799, "IBRANCE": 0.8772237462260001, "INSULIN": 3.9064654944551984, "ISCOVER": 10.8854025500992, "JARDIANCE": 0.3174880728252854, "LANTUS": 8.693643771959087, "LEVEMIR": 3.069955587159581, "LIXIANA": 11.539768936071326, "MAYZENT": 77.41697412515178, "MEKINIST": 0.7561057462374091, "NEVANAC": 6.632189376763898, "NEXAVAR": 0.4811246761282907, "OMALIZUMAB": 0.6146757491091174, "PEGASYS": 1.2143532333552318, "PEGINTRON": 0.5281186181655378, "PLAVIX": 9.71948768296904, "REVATIO": 1.801388669231104, "ROACTEMRA": 0.9004055403123451, "SHINGRIX": 0.5772889759175094, "SILDENAFIL": 3.3388178219758973, "SIMPONI": 0.4166172330335461, "SPIKEVAX": 0.4200675165263061, "SPRYCEL": 2.0008541084455365, "STELARA": 0.2964063025260505, "SUTENT": 1.2550616708752191, "TASIGNA": 0.6928967418013167, "TICAGRELOR": 2.471622456330378, "TOUJEO": 3.167798709297984, "TOVIAZ": 1.4622829554931742, "TOZINAMERAN": 0.9665379413243798, "TRELEGY": 3.2798182269059546, "TRULICITY": 1.9250460646652048, "VAXZEVRIA": 0.7019135458728736, "VIAGRA": 4.327113849497902, "VICTOZA": 1.2230198870312197, "VOTRIENT": 0.7193732317558749, "XARELTO": 2.640729038651833, "XELJANZ": 0.6242926126320598, "XYREM": 3.0555226287267105, "ZOSTAVAX": 0.2947515263579772, "null": 0.72287405424223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4445.json
index c4f0f6eb737..8cd214c405e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4445.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4445.json
@@ -1 +1 @@
-{"BUVIDAL": 2.733437071209195, "COMIRNATY": 3.2894829813855164, "COVID19": 3.0707008169526326, "MENQUADFI": 9.453555700609286, "MENVEO": 1.2364376268601434, "MMRVAXPRO": 2.2419999128532435, "NIMENRIX": 7.818587907676562, "PLEGRIDY": 2.4432155385051733, "ROTARIX": 5.178936562105896, "SAXENDA": 1.919618502356887, "SHINGRIX": 2.3752134852848696, "SPIKEVAX": 11.3519024947709}
\ No newline at end of file
+{"COMIRNATY": 4.7813522757945055, "SPIKEVAX": 2.6120842747459743, "VAXZEVRIA": 1.1136873366626592, "null": 0.1452992480431593}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4446.json
index 40a2af1e226..8851c82524b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4446.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4446.json
@@ -1 +1 @@
-{"ABATACEPT": 5.999450956616284, "ABLAVAR": 405.3413816831731, "ADALIMUMAB": 10.371579466868871, "ADVATE": 4.187367198535719, "APREMILAST": 10.427894900771989, "APREPITANT": 17.91978046365896, "ARAVA": 1.145646531463966, "AVANDAMET": 6.082735841414787, "AVANDIA": 12.57712977984629, "BUPRENORPHINE": 1.0683060176567396, "CELECOXIB": 5.686614070471255, "CONTRAST": 10.158087729769807, "COSENTYX": 1.556578963060003, "DAPAGLIFLOZIN": 3.757761137938656, "DULOXETINE": 2.093390179146755, "ELIQUIS": 1.2852258788896247, "ERELZI": 4.908372873509432, "FENTANYL": 1.1648717240420992, "HEMLIBRA": 8.666863564110663, "HUMALOG": 1.0160617063408874, "INSULIN": 4.161797213186596, "LYRICA": 1.1417674317424886, "MEPOLIZUMAB": 1.256668535189781, "OPTIMARK": 49.84857623410041, "PLAVIX": 3.6589711094991326, "SUBOXONE": 1.3643409055068667, "TASIGNA": 20.58623093858763, "VIAGRA": 1.2105176402280984, "VIMPAT": 1.543620291707032, "ZOSTAVAX": 1.7286683467455697, "null": 1.8872229122516384}
\ No newline at end of file
+{"ARAVA": 1.1775860506148277, "BENLYSTA": 4.737690334207903, "CIMZIA": 2.0049306453959512, "COMIRNATY": 0.4182532675434971, "COSENTYX": 3.041020101776579, "CYMBALTA": 0.6759962160389188, "DUPIXENT": 54.53690993932045, "EYLEA": 39.06240770945119, "FORSTEO": 1.3109076054755375, "HIZENTRA": 5.554562477972983, "HUMALOG": 1.1382833890968331, "HUMIRA": 2.6482211812758667, "IBRANCE": 1.1914701098380651, "LANTUS": 2.51236302896192, "PEGASYS": 0.994097705707596, "REVATIO": 6.816912119640038, "RITUXIMAB": 4.705968500043808, "SIMPONI": 7.01156122951659, "SPIKEVAX": 0.3249672174194237, "SUTENT": 0.4088054515201731, "TOZINAMERAN": 0.6750824424344688, "VAXZEVRIA": 0.3961403594152133, "XELJANZ": 7.879992738330348, "ZOSTAVAX": 4.79915446314359, "null": 0.9274519316318248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4447.json
index f822930e085..5f1bb2ebe27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4447.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4447.json
@@ -1 +1 @@
-{"ABASAGLAR": 22.5503474954124, "AIMOVIG": 2.901570474306605, "BYDUREON": 7.308267553787056, "FORSTEO": 6.15273551830467, "HUMALOG": 14.483456703818993, "INSULIN": 7.990588753491875, "LANTUS": 11.233303795427672, "PLEGRIDY": 55.45000510044364, "ROACTEMRA": 6.305817697059696, "SIMPONI": 21.941792102594867, "STELARA": 1.9723409994973584, "TRULICITY": 8.359553808840856, "null": 1.8338396172506728}
\ No newline at end of file
+{"EYLEA": 129.10181067704144, "null": 0.7483774734137085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4448.json
index fb76b371c2a..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4448.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4448.json
@@ -1 +1 @@
-{"null": 1.403941172460353}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4449.json
index b99c5c2374b..aaa9cb817ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4449.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4449.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1460087781851926, "TOZINAMERAN": 1.7173535809386264}
\ No newline at end of file
+{"ANIDULAFUNGIN": 1305.0195962222592, "null": 0.7901095206882638}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/445.json
index 3423a0a24f4..ae5e78d87aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/445.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/445.json
@@ -1 +1 @@
-{"CELLCEPT": 6.157952096204422, "CICLOSPORIN": 6.836616304601608, "COMBIVIR": 37.16774233533396, "GARDASIL": 72.65606894254631, "KALETRA": 55.25217805853367, "SILGARD": 347.5575008371184, "STELARA": 7.007751084239879}
\ No newline at end of file
+{"null": 9.456345772971655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4450.json
index 3e1efaca33b..53018e3eb5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4450.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4450.json
@@ -1 +1 @@
-{"SPIKEVAX": 2.313142173174804, "TOZINAMERAN": 4.801069340858438}
\ No newline at end of file
+{"RIBAVIRIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4451.json
index 086f47552ca..f6750624e19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4451.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4451.json
@@ -1 +1 @@
-{"ABATACEPT": 1.459008517299552, "ABILIFY": 2.223457826243262, "ACLIDINIUM": 1.3427970547797885, "ADALIMUMAB": 1.2797811282943432, "AERIUS": 1.6501602274289853, "AIMOVIG": 1.3890874730445364, "ALDARA": 1.133991707216998, "ANTIBIOTICS": 1.452253455126849, "APIXABAN": 2.553126197783168, "ARAVA": 1.5290678727323892, "ARIPIPRAZOLE": 1.3907325213357935, "AVONEX": 1.38431451039445, "AZILECT": 1.4663927556213392, "BETMIGA": 1.977206930547779, "BIKTARVY": 2.9426045212257823, "BOCEPREVIR": 1.2167405377338192, "BRINTELLIX": 3.288150674753925, "BRIVIACT": 2.1775347078402607, "BUPRENORPHINE": 1.0922845388570397, "BUVIDAL": 1.8492004190161715, "CABOTEGRAVIR": 1.3868661004745142, "CANNABIDIOL": 1.0342983855922578, "CAPRELSA": 1.0426653089285434, "CARIPRAZINE": 3.116797218493686, "CHAMPIX": 5.450849072498638, "CHLORHEXIDINE": 1.4734858096764574, "CIMZIA": 1.2591680510596768, "CIRCADIN": 3.0486810359517484, "COMPLEMENT": 3.4531784156906857, "COMTAN": 1.416106092017598, "CYMBALTA": 6.038909904020921, "DAKLINZA": 3.096398410062133, "DALIRESP": 1.9278503423776745, "DELTYBA": 2.112522584101962, "DESCOVY": 1.1120174806836125, "DESLORATADINE": 1.573088658373742, "DULOXETINE": 1.1460639335647027, "EDURANT": 1.6728523366784025, "ENTACAPONE": 1.506737492744059, "EPCLUSA": 1.2815520789569352, "ERENUMAB": 1.2048082866919532, "ESBRIET": 1.2689055100846065, "EXVIERA": 1.2669271956820851, "FAMPRIDINE": 1.218319703655374, "FAMPYRA": 4.463119712970041, "FIRDAPSE": 1.1948858437898806, "FUZEON": 4.998444574232191, "FYCOMPA": 1.4367158314298287, "GALAFOLD": 1.0998373133607309, "GENVOYA": 1.2394348584738002, "HARVONI": 1.6533352902769334, "HYDROCHLOROTHIAZIDE": 1.176922276652605, "HYDROCORTISONE": 1.5579752624857517, "IBRANCE": 1.031485040129762, "ILARIS": 5.302679487247665, "INCIVO": 1.1246940747498937, "INFERGEN": 2.2877596567567324, "INTELENCE": 1.036965542755596, "INTERFERON": 1.0743368551941073, "INTRONA": 2.6949970071165663, "INVEGA": 2.1794372703530467, "IRON": 1.2697489209863224, "IVACAFTOR": 9.916105429983393, "IXIARO": 1.8998769354249787, "KAFTRIO": 2.5674365980347686, "KEPPRA": 1.5207806424126988, "KIVEXA": 1.544216761571487, "LATUDA": 3.4342148837405047, "LEFLUNOMIDE": 1.232301587758197, "LEMTRADA": 1.0174451249661058, "LEVODOPA": 1.5119847351206896, "LYRICA": 1.714707946365185, "MELATONIN": 5.399498417560318, "MICARDIS": 1.1805827757995748, "NEUPRO": 1.6690210501078957, "OCALIVA": 1.119460479155193, "OCRELIZUMAB": 1.7265745670220911, "OLANZAPINE": 1.3950115967104564, "OLYSIO": 1.4714657216814773, "OMALIZUMAB": 1.1484153663290375, "ORENCIA": 1.1413819958189462, "OTHER": 2.366340398865943, "OXYBUTYNIN": 1.2342027260463198, "PEGASYS": 3.0587966948514373, "PEGINTERFERON": 1.7104166832032248, "PEGINTRON": 2.478233936671585, "PIRFENIDONE": 1.0937617258238603, "POPPERS": 3.797002348937057, "PRAMIPEXOLE": 2.9811683868457397, "PROPRANOLOL": 1.1270879740775506, "PROTOPIC": 2.8210568535750125, "RANEXA": 1.0257998192083797, "REAGILA": 3.079737385748317, "REBETOL": 1.8682395545701809, "RIBAVIRIN": 1.422344847336927, "RISPERIDONE": 1.246171608153881, "RUBRACA": 1.0673544999933195, "SEEBRI": 2.8428971111175256, "SIFROL": 2.737387988726551, "SOFOSBUVIR": 1.65656987324885, "SOVALDI": 1.4031550827496908, "STALEVO": 1.1108059526207004, "STOCRIN": 2.223301781918884, "SUBOXONE": 2.4162344840547383, "SYCREST": 2.409123188764614, "SYMTUZA": 1.903405340308017, "TAMIFLU": 1.5299215607587353, "TECFIDERA": 1.7087842576001495, "TEDUGLUTIDE": 2.7702106056602864, "TIVICAY": 3.201936467142211, "TOVIAZ": 1.6781357148159195, "TOZINAMERAN": 1.3169853545498782, "TRIUMEQ": 7.11788095279899, "UNSPECIFIED": 1.0074221866217017, "VALDOXAN": 2.002242225988651, "VARENICLINE": 3.577180527438575, "VFEND": 1.40100382711106, "VIMPAT": 1.170231369704411, "VORTIOXETINE": 2.0445821955698618, "WAKIX": 5.2608246701273504, "XTANDI": 1.516321467234659, "XYREM": 2.416921029873992, "ZEJULA": 2.8234805089933075, "ZEPATIER": 2.221148345960796, "ZOSTAVAX": 1.7164075393261793, "ZYCLARA": 1.1117989732584057, "ZYPREXA": 1.3028245923075392, "null": 1.127413243586627}
\ No newline at end of file
+{"EYLEA": 87.93990329567666, "null": 7.608905319430579}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4452.json
index 8723a04d43a..eb39a00c3c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4452.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4452.json
@@ -1 +1 @@
-{"BUDESONIDE": 79.49867101686598, "FENTANYL": 193.44620542160672}
\ No newline at end of file
+{"EYLEA": 454.56823802190894, "null": 0.5424216843027951}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4453.json
index 84b0973d93d..029f07adf18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4453.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4453.json
@@ -1 +1 @@
-{"null": 4.9551076627161}
\ No newline at end of file
+{"ARAVA": 0.1359506035394161, "AVASTIN": 2.3859760867463984, "BEOVU": 327.8943497620763, "BROLUCIZUMAB": 266.51048458961844, "CICLOSPORIN": 1.1199021480250608, "CIMZIA": 0.4185417458153129, "COMIRNATY": 0.8741634535669771, "COSENTYX": 1.6551712844715394, "ENTYVIO": 1.4525628223869698, "EYLEA": 254.59335269455383, "LANTUS": 0.2725496258572773, "MMRVAXPRO": 5.861368482614195, "NEVANAC": 19.05092008840178, "PEGASYS": 0.295316195373307, "SHINGRIX": 1.4425181225930015, "SIMPONI": 1.023935596512814, "SPIKEVAX": 0.5817954901278771, "SUTENT": 0.2570384094874257, "TOZINAMERAN": 0.7662781507378447, "VAXZEVRIA": 0.3187979336068449, "XELJANZ": 0.6488086162110163, "XOLAIR": 0.5735612987437352, "ZOSTAVAX": 0.775969011241903, "null": 0.752387504768439}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4454.json
index 7efa8018aa3..8b684609b43 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4454.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4454.json
@@ -1 +1 @@
-{"null": 3.5148518229747605}
\ No newline at end of file
+{"ADALIMUMAB": 24.46119448188546, "AVANDIA": 1.8747662521689687, "BEOVU": 21.658271422350285, "CLOPIDOGREL": 1.7371665884101692, "COMIRNATY": 0.1321130122781032, "ENBREL": 1.7931279777124167, "EYLEA": 8.226479915143292, "HUMALOG": 3.8099002206789296, "HUMIRA": 10.65668846581266, "KEPPRA": 1.2606118549081546, "LANTUS": 2.05895539903638, "NEVANAC": 44.86974810301137, "SPIKEVAX": 0.20186514119534, "SUTENT": 0.9798149724813114, "TOZINAMERAN": 2.3565603792933043, "VAXZEVRIA": 0.6576857694285332, "ZOSTAVAX": 2.877294585578737, "null": 0.6316618815004958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4455.json
index be519d6896b..8fb992df917 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4455.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4455.json
@@ -1 +1 @@
-{"ORENCIA": 5488.458910089917}
\ No newline at end of file
+{"ABILIFY": 0.8610318568887092, "ADALIMUMAB": 0.1298056111270014, "AIMOVIG": 0.9896653613237434, "ANORO": 1.6441822108685658, "ARAVA": 0.1743766821517618, "ARIPIPRAZOLE": 0.6239615399890339, "AVASTIN": 0.8283586646179465, "AZOPT": 11.497342259300076, "BEOVU": 15.833640763139837, "BRIMONIDINE": 67.0115553044586, "BRINTELLIX": 0.7292013408706464, "CHAMPIX": 0.430056631701662, "CHLORHEXIDINE": 1.8508318569471096, "CICLOSPORIN": 0.4978665038003219, "CIMZIA": 0.1869971373056205, "COMIRNATY": 0.9670902148702316, "COSENTYX": 0.4924349520499162, "CYMBALTA": 0.241156948245977, "DEXAMETHASONE": 0.3968444625983841, "ELIQUIS": 0.5046925009373702, "ENTYVIO": 1.292472638331769, "EXJADE": 0.4329508802324454, "EYLEA": 10.467002038390886, "FORSTEO": 0.4120230834642314, "GARDASIL": 0.4454844243710536, "HUMALOG": 0.3334126481451194, "IBRANCE": 0.6021658994826635, "IKERVIS": 324.3741309271525, "KEPPRA": 0.2284150068662125, "LANTUS": 0.3674710610809316, "LIXIANA": 1.455601730775199, "LUCENTIS": 27.923730388082124, "LYRICA": 0.6101186883055316, "MEKINIST": 0.6451984251867917, "MEPOLIZUMAB": 2.1513185143671967, "METHOTREXATE": 0.9892724370779896, "NEVANAC": 69.30522951896134, "NUCALA": 0.4859145789577614, "OMALIZUMAB": 0.6645142200674605, "OPATANOL": 91.33153698774557, "PEGASYS": 1.0928393686859446, "PEGINTERFERON": 1.4037246746043497, "PEGINTRON": 0.2471458201788767, "QUTENZA": 24.07825256900238, "SHINGRIX": 1.1996086064259095, "SIMPONI": 0.5516397801610761, "SPIKEVAX": 0.6834576818752836, "STELARA": 0.3134856874013392, "SUTENT": 0.6362947790449666, "TOZINAMERAN": 1.110755387349109, "TRELEGY": 1.1152436171226734, "VAXZEVRIA": 0.7661233295258109, "VIAGRA": 1.3108774173268734, "XELJANZ": 0.7224294628907962, "XOLAIR": 0.6467201895110585, "ZOSTAVAX": 1.1786430108284438, "null": 1.974162266355164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4456.json
index 25f0a4d43fe..ffd5c0dcbea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4456.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4456.json
@@ -1 +1 @@
-{"null": 4.469397015128806}
\ No newline at end of file
+{"HUMALOG": 12.7280785954752, "LANTUS": 19.88411647407262, "null": 1.1881845312437305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4457.json
index d4ccf3c855d..9241be38556 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4457.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4457.json
@@ -1 +1 @@
-{"null": 1.5866082288418275}
\ No newline at end of file
+{"null": 1.4285586325439394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4458.json
index 04f83c0802b..ec9a3ff6596 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4458.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4458.json
@@ -1 +1 @@
-{"null": 2.119843710264686}
\ No newline at end of file
+{"ABILIFY": 1.1255435321175018, "ARIPIPRAZOLE": 1.0956966739015226, "AUBAGIO": 1.977697527141555, "BEXSERO": 10.154305405513805, "CICLOSPORIN": 1.1608926245754911, "COMIRNATY": 0.4049697474396346, "COSENTYX": 0.690862757649213, "CYMBALTA": 0.7406001132453681, "DEXAMETHASONE": 0.779694303308586, "FIRDAPSE": 5.286820300412947, "GARDASIL": 10.217407710713417, "INFANRIX": 17.36099878463675, "INSULIN": 1.2884760783676967, "KEPPRA": 1.248977834488138, "KEYTRUDA": 0.3694924988272646, "LACOSAMIDE": 4.374897332151165, "LATUDA": 2.780552109262024, "LEVETIRACETAM": 1.635903489131875, "MENVEO": 10.952024416446344, "MMRVAXPRO": 3.96700055365045, "NIMENRIX": 6.689054600506044, "OLANZAPINE": 2.0719253561255173, "PEGASYS": 0.2592314196964412, "PREVENAR": 6.291801470622841, "ROTATEQ": 3.0815105586530165, "SHINGRIX": 0.6276010223821699, "SODIUM": 46.17764180242136, "SPIKEVAX": 0.6434153257014349, "TAMIFLU": 2.1886468204294136, "TOZINAMERAN": 1.1390387255703078, "VAXZEVRIA": 0.2680999239540735, "ZYPREXA": 2.5836841658192555, "null": 2.1295823584131366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4459.json
index e9130e7d96e..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4459.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4459.json
@@ -1 +1 @@
-{"null": 1.3445297455178007}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/446.json
index b7cb1243586..a297c23f8cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/446.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/446.json
@@ -1 +1 @@
-{"null": 4.819314099548674}
\ No newline at end of file
+{"ABILIFY": 7.59322655372163, "COMIRNATY": 0.4083134312115462, "GARDASIL": 5.06044881761342, "IBUPROFEN": 9.175357807641348, "OMALIZUMAB": 59.32984910299365, "PANTOPRAZOLE": 47.71046067868815, "SPIKEVAX": 0.248610835335859, "UMECLIDINIUM": 165.87961332744771, "XOLAIR": 5.336252706063613, "null": 0.8429583319264742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4460.json
index 5745783844f..e2c217d5419 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4460.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4460.json
@@ -1 +1 @@
-{"COVID19": 5.130234219942129}
\ No newline at end of file
+{"BEOVU": 17.22268823265324, "CHAMPIX": 1.0581254128237534, "COMIRNATY": 0.7937805965204201, "ENTRESTO": 1.6101584302951215, "EYLEA": 13.806020929066651, "LANTUS": 0.6113147457720464, "PEGASYS": 0.5921298495345593, "SPIKEVAX": 0.4732533080548364, "SUTENT": 1.5110205953573057, "TOZINAMERAN": 0.4453571504000385, "VAXZEVRIA": 0.4352082654388898, "XOLAIR": 3.103130538697072, "null": 2.2139431761464445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4461.json
index 6bdd8c7bad5..b367b94ef2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4461.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4461.json
@@ -1 +1 @@
-{"HUMALOG": 30.74465337518028, "INSULIN": 47.0287744961078, "JARDIANCE": 30.53262809322468}
\ No newline at end of file
+{"null": 0.475439175831845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4462.json
index b4d93d74fc0..f7d1a5b96a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4462.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4462.json
@@ -1 +1 @@
-{"INSULIN": 88.05675507795686}
\ No newline at end of file
+{"ELIQUIS": 1.6532293959142337, "ENBREL": 5.336320250511881, "EYLEA": 8.09754900950883, "HUMALOG": 2.9593643185148477, "IBRANCE": 6.490012724115688, "JANUMET": 8.14579865997022, "JARDIANCE": 2.21761798694538, "LANTUS": 18.480510826475577, "LEVEMIR": 5.945705847507709, "OPSUMIT": 2.902301506951632, "SIMPONI": 7.681805732137042, "STELARA": 1.826752057931899, "VELTASSA": 25.131552688500403, "XELJANZ": 4.18850389425756, "ZOSTAVAX": 2.33130828970675, "null": 1.3069550972603403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4463.json
index 1f387be08e7..2adc7aaedf3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4463.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4463.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 41.55928355147467, "INSULIN": 56.51647284079366, "LANTUS": 4.587491908736293, "null": 1.6441199628915972}
\ No newline at end of file
+{"ABILIFY": 0.2569073993897314, "ADALIMUMAB": 0.400102294965193, "AIMOVIG": 1.0926342490702774, "ALDARA": 1.6843322828019125, "ALEMTUZUMAB": 0.5011289080222692, "APIDRA": 0.3368923875376223, "ARAVA": 0.0534253505514704, "AUBAGIO": 0.6902155845513284, "AVAMYS": 0.7667846718738909, "AVANDIA": 0.1088363530873645, "AVASTIN": 1.012324497095138, "AZILECT": 5.332908202461363, "AZOPT": 8.844785519530927, "BAQSIMI": 11.729345344384743, "BELIMUMAB": 1.8964228116152468, "BENLYSTA": 0.4863967982897061, "BEOVU": 25.685321557989138, "BETMIGA": 0.8242893442208595, "BIKTARVY": 0.4905478189001815, "BRAFTOVI": 0.3843776604992325, "BRIMONIDINE": 12.531858574035065, "BRINTELLIX": 1.1211586718568265, "BROLUCIZUMAB": 35.02150537037874, "BYDUREON": 2.0652645378464345, "CELLCEPT": 0.1636255041750323, "CHAMPIX": 1.3004537172366235, "CHLORHEXIDINE": 0.5928398073397496, "CICLOSPORIN": 0.4794386447337769, "CIMZIA": 0.1039646653044752, "CLOPIDOGREL": 0.1891268748931996, "COMIRNATY": 1.384266548168229, "COSENTYX": 0.3131588402082164, "CYMBALTA": 0.5218726710126893, "CYTARABINE": 0.1603664868090724, "DEXAMETHASONE": 0.3359444404910471, "DOCETAXEL": 0.3311518493930605, "DUPIXENT": 4.082846102819229, "ELIQUIS": 0.1972555209939019, "ENBREL": 0.1545537438199382, "ENTRESTO": 0.2759345616161255, "ENTYVIO": 0.4675589530871188, "ERENUMAB": 2.568265196173149, "ESBRIET": 0.2870578969911951, "EXFORGE": 0.4511570073283989, "EXJADE": 0.1946491812943734, "EYLEA": 28.5941522060994, "FAMPYRA": 0.3539729047547564, "FASENRA": 0.3153978101455555, "FASLODEX": 0.1983299956747304, "FENTANYL": 0.1837234231854621, "FORSTEO": 0.2197168513415056, "GARDASIL": 1.290570400709379, "HUMALOG": 0.3664667467940445, "HUMIRA": 0.3375933152250402, "HYDROCHLOROTHIAZIDE": 4.479097198272771, "HYDROCORTISONE": 1.2419135979611071, "IBRANCE": 0.2772240992463774, "IBUPROFEN": 0.3331461220098909, "IKERVIS": 72.48049292124732, "INCRUSE": 2.534808443364394, "INTELENCE": 2.7160391488955344, "JANUVIA": 0.28457301361317, "JARDIANCE": 0.0766609552533305, "JETREA": 15.376187844445644, "KAFTRIO": 0.5112762199013653, "KEPPRA": 0.3325645583180557, "KEYTRUDA": 0.0894591678798818, "LAMIVUDINE": 0.617453904675363, "LANTUS": 0.2109796130425817, "LEMTRADA": 0.5543384480463636, "LEVOFLOXACIN": 0.1764863524854481, "LUCENTIS": 17.82701144203305, "LYRICA": 0.6735195627862044, "MAVENCLAD": 1.541945447450353, "MEKINIST": 0.5568932594682136, "MEPOLIZUMAB": 0.1696449217054631, "METHOTREXATE": 0.247854141209632, "MMRVAXPRO": 0.4169175035574501, "MODERNA": 0.9229700179476394, "MYCOPHENOLATE": 1.210191481412729, "NEPAFENAC": 23.506506338721024, "NEVANAC": 17.243385244591956, "NEXAVAR": 0.1314924363015889, "NIMENRIX": 1.3017603402077809, "NUCALA": 0.1894167258456417, "OCRELIZUMAB": 3.298709203934587, "OLANZAPINE": 0.12597443540613, "OMALIZUMAB": 0.25903801671251, "OPATANOL": 21.302859423327806, "OPSUMIT": 0.2728080925788382, "PEGASYS": 0.9573374229989392, "PEGINTERFERON": 0.3526223520281323, "PEGINTRON": 0.9619108219445666, "PLAVIX": 0.2288681930854128, "PLEGRIDY": 0.7226164617757977, "PREGABALIN": 1.4637396041405493, "PRIVIGEN": 0.4460404510396343, "QUTENZA": 4.123300743251277, "REVATIO": 0.3973186088601386, "RINVOQ": 0.451687878787826, "ROACTEMRA": 0.2994951465818985, "SHINGRIX": 1.2263613588985132, "SILDENAFIL": 0.5006240690702066, "SIMPONI": 0.2960193711091827, "SOLIRIS": 0.1682549037945908, "SPIKEVAX": 1.1493308361548398, "STELARA": 0.8335681211197267, "SUTENT": 0.2345137158912047, "TAMIFLU": 0.4125334417147163, "TASIGNA": 0.5952092226532872, "TELMISARTAN": 1.6367263982292557, "TOBRAMYCIN": 3.4165936959212977, "TOUJEO": 0.6359782178824194, "TOVIAZ": 0.9511488598323018, "TOZINAMERAN": 2.555395837569119, "TRELEGY": 1.1267690171488138, "TWINRIX": 0.7499375622595829, "VAXZEVRIA": 3.405283180857132, "VFEND": 0.457506229691987, "VIAGRA": 1.121961660430734, "VORICONAZOLE": 0.7906494348962773, "VOTRIENT": 0.1401364959089517, "XELJANZ": 0.383643670842603, "XOLAIR": 0.2339537781844213, "XTANDI": 0.1501156544749426, "ZOSTAVAX": 1.0733099710026883, "ZYPREXA": 0.2065268432529982, "null": 0.707962479867774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4464.json
index e4db3f13cb5..122d3cb2a52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4464.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4464.json
@@ -1 +1 @@
-{"ACTRAPID": 21.031783213450478, "APIDRA": 9.37935011209292, "BYETTA": 4.568946468936606, "FIASP": 56.18370107771618, "GARDASIL": 2.472983569635918, "HUMALOG": 57.62930720467428, "INSULIN": 46.788192016979416, "LANTUS": 7.143135981648835, "LEVEMIR": 14.961892558651355, "NOVORAPID": 17.916036704348898, "SOMATROPIN": 35.62490278094377, "ZYPREXA": 3.889250128705401}
\ No newline at end of file
+{"COMIRNATY": 2.4508586984643026, "NUCALA": 34.24220619107173, "null": 0.5795561120506747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4465.json
index 4a7d7c79f0a..8f02bc20044 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4465.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4465.json
@@ -1 +1 @@
-{"HUMALOG": 78.20262167219502}
\ No newline at end of file
+{"AIMOVIG": 1.139241357521463, "APIXABAN": 21.31575361979321, "AVAMYS": 3.405531875851113, "BUDESONIDE": 13.378025729940962, "CARBIDOPA": 19.908613523330867, "CHAMPIX": 0.3124887561619919, "CICLOSPORIN": 0.3042822389387998, "CIMZIA": 0.414678415118174, "CLOPIDOGREL": 0.5167250579123522, "COMIRNATY": 0.8906358640194595, "COSENTYX": 0.7845837645084571, "ELIQUIS": 0.3936097892921039, "ESBRIET": 0.837420392232316, "EYLEA": 1.371917734150654, "FASENRA": 1.2758669036721386, "FLUTICASONE": 33.871060887724845, "GARDASIL": 0.5475471168597712, "HUMIRA": 0.553628764459483, "IBRANCE": 0.8444107350686778, "IKERVIS": 51.54901934553404, "KEPPRA": 0.4146942253304562, "LANTUS": 0.2396566032991958, "LEVOFLOXACIN": 0.34261026217822, "MEPOLIZUMAB": 8.665417544561432, "MMRVAXPRO": 1.0328595437531964, "NEVANAC": 9.125705316705805, "NUCALA": 16.467247757577596, "OLANZAPINE": 0.5342038131114745, "OMALIZUMAB": 2.4847970967554747, "OPATANOL": 79.82687449024846, "PANTOPRAZOLE": 3.072309767242324, "PEGASYS": 0.9026359208203908, "PEGINTERFERON": 0.9458975636751586, "QUTENZA": 4.7326865192753935, "RELVAR": 1.943796191061305, "RITUXIMAB": 1.6413841027891294, "SHINGRIX": 0.5150694100074616, "SIMPONI": 0.4523934278268083, "SPIKEVAX": 0.4855262619231238, "STELARA": 0.4258435120815647, "SUTENT": 0.2237669702138099, "TASIGNA": 0.618256782246162, "TOZINAMERAN": 1.6578988910210235, "TRELEGY": 0.9731989127745824, "VAXZEVRIA": 0.5711948037960052, "XELJANZ": 0.5849098246992005, "XOLAIR": 4.486953457092273, "ZOSTAVAX": 1.0281392648116294, "null": 1.3942725482544844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4466.json
index 958942651d2..35bc366fb49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4466.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4466.json
@@ -1 +1 @@
-{"null": 1.4952445862083286}
\ No newline at end of file
+{"AERIUS": 1.418657739412724, "AFINITOR": 0.3637902149292779, "AIMOVIG": 0.3421295909316569, "ARANESP": 0.290634668761396, "AVANDIA": 0.2552735031604622, "BENLYSTA": 0.6173796589657646, "BETMIGA": 3.440645511527012, "BOSULIF": 1.242269307226885, "BUDESONIDE": 0.29505863806597, "BYDUREON": 0.9605751403789408, "CHAMPIX": 0.9166767815165652, "CICLOSPORIN": 0.8501586191173024, "CIMZIA": 0.4332158821604027, "CLOPIDOGREL": 0.310449157694709, "COMIRNATY": 0.9096757167574776, "COSENTYX": 0.6830191905171503, "CYMBALTA": 0.2659636473764928, "DARZALEX": 0.9191184688624576, "DELAMANID": 2.412843267848349, "DEXAMETHASONE": 0.5306664759166877, "ELIQUIS": 0.2892365188129619, "ENBREL": 0.218231282654716, "ENTRESTO": 1.016068785537482, "EXFORGE": 1.8060976558845525, "EXJADE": 0.2908162822255358, "EYLEA": 3.95927258470806, "FASENRA": 0.9818923742136192, "FASLODEX": 0.4651798791247254, "FENTANYL": 0.415396500649989, "FORSTEO": 0.5887634257501245, "GARDASIL": 1.3130896097401217, "HIZENTRA": 1.2643287128389282, "HUMALOG": 0.7302400797439575, "HUMIRA": 0.6172756108639956, "HYDROCORTISONE": 1.8717794145278592, "IBRANCE": 0.1982093073812295, "IBUPROFEN": 0.9915355516223168, "IKERVIS": 16.442496623357297, "IRBESARTAN": 1.0157569520908245, "JANUVIA": 0.3970407329056611, "JARDIANCE": 0.2477389708403459, "KEPPRA": 0.1901425563570842, "KEYTRUDA": 0.1263175664005683, "LANTUS": 0.8866970890598365, "LATUDA": 0.6163191374257363, "LEVOFLOXACIN": 0.2788053204061756, "METHOTREXATE": 0.3121747607112435, "MMRVAXPRO": 1.34892307559695, "NEULASTA": 0.910496675261114, "NEVANAC": 9.686785587428348, "NEXAVAR": 0.2509732026415099, "NIMENRIX": 1.3156052563691825, "NUCALA": 4.587831830205932, "OCRELIZUMAB": 0.6295463118581559, "OMALIZUMAB": 2.5476546693960875, "OPATANOL": 22.69356933040864, "PEGASYS": 1.3129412125358102, "PEGINTRON": 0.4969464838027114, "PLAVIX": 0.3284916960559183, "RASILEZ": 1.3207862192428377, "REVATIO": 0.8329478298736217, "RINVOQ": 1.4426976357074386, "SHINGRIX": 1.2757222969740856, "SIMPONI": 0.3975454732330184, "SOLIRIS": 0.3527334434724203, "SPIKEVAX": 0.8420828285345423, "SPRYCEL": 1.2869350735825291, "STELARA": 0.6555497841105132, "SUBOXONE": 0.3475058044659124, "SUTENT": 2.5023148809084, "TAMIFLU": 1.1054504871827124, "TASIGNA": 0.3971543946619585, "TOBRAMYCIN": 3.379485528471644, "TOVIAZ": 0.8380983565348656, "TOZINAMERAN": 2.797736897130525, "TRELEGY": 0.5642727031107224, "TRULICITY": 0.4090715213049147, "TWINRIX": 1.4416614419850546, "VAXZEVRIA": 0.9668192326963726, "VFEND": 0.5609746036594445, "VIAGRA": 0.6165613371605781, "XELJANZ": 0.6530306482411755, "XOLAIR": 2.607784550082871, "XTANDI": 0.2242812916718834, "ZOSTAVAX": 0.5822798078256333, "null": 1.5903106289268534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4467.json
index e1ac575da38..465987736b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4467.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4467.json
@@ -1 +1 @@
-{"null": 4.920891343497318}
\ No newline at end of file
+{"BRAFTOVI": 50.00329232035875, "COMIRNATY": 0.6659745444605629, "VAXZEVRIA": 0.9759826991652634, "null": 0.6812926852352392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4468.json
index 50abe5b4fd9..5a03607bfd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4468.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4468.json
@@ -1 +1 @@
-{"SOMATROPIN": 278.57056558083264, "SOMAVERT": 2152.5677485815067, "null": 4.910833575490411}
\ No newline at end of file
+{"VAXZEVRIA": 0.5596464003010996, "null": 0.4191079007873347}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4469.json
index 5f1f2d901d9..a1fe3e29ea6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4469.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4469.json
@@ -1 +1 @@
-{"BYDUREON": 31.5742236418412, "BYETTA": 102.04665456066388, "JANUMET": 60.31980507685837, "JANUVIA": 66.15063661684395, "ZYPREXA": 19.914807531028707}
\ No newline at end of file
+{"SUTENT": 44.67334519262169, "VOTRIENT": 56.772157237581325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/447.json
index 9d7b703bf5f..2f8fe7d66ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/447.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/447.json
@@ -1 +1 @@
-{"null": 4.347186733757916}
\ No newline at end of file
+{"COMIRNATY": 1.745225308161554, "TOZINAMERAN": 2.3771964655128923, "null": 0.2558946046788492}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4470.json
index 63a13b8a0e8..14884918d1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4470.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4470.json
@@ -1 +1 @@
-{"IRBESARTAN": 188.33467845780336}
\ No newline at end of file
+{"COMIRNATY": 0.9230752942523928, "VAXZEVRIA": 1.727221542588138}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4471.json
index ab031ab6058..d86924733d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4471.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4471.json
@@ -1 +1 @@
-{"ABILIFY": 35.8062619548615, "BYDUREON": 13.116615424905246, "CIMZIA": 41.84917315920302, "FASENRA": 27.6214310630625, "HIZENTRA": 30.638194974535697, "JANUVIA": 3.355479327212588, "OCALIVA": 28.186777059639294, "RUCONEST": 52.37275706918357, "null": 1.6501135575599386}
\ No newline at end of file
+{"VAXZEVRIA": 2.9737956339659952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4472.json
index fca8baa17f3..3d85f5c133a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4472.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4472.json
@@ -1 +1 @@
-{"AVAMYS": 4.295055557915918, "CICLOSPORIN": 1.9098434336444576, "COMBIVIR": 5.824935971387321, "KEPPRA": 2.9869003578834934, "LEVETIRACETAM": 15.112956368947549, "null": 5.877015326170559}
\ No newline at end of file
+{"VAXZEVRIA": 1.850010924805414, "null": 0.4064585265653785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4473.json
index 0edc42a44e9..4b347af55bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4473.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4473.json
@@ -1 +1 @@
-{"null": 4.593336151050352}
\ No newline at end of file
+{"ARAVA": 2.780363366325544, "BUDESONIDE": 3.8300227755115928, "COMIRNATY": 0.3554787094886403, "ELIQUIS": 1.245363772097721, "MELATONIN": 32.09118561280188, "SPIKEVAX": 0.4238248103515367, "SUTENT": 1.635400489642056, "TOZINAMERAN": 1.9079150824817868, "VAXZEVRIA": 0.2779367617468252, "null": 1.227999655082375}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4474.json
index 0fa357203a5..6aff4266573 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4474.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4474.json
@@ -1 +1 @@
-{"BRIDION": 20.36594354562773, "GARDASIL": 10.340098354904514, "KAFTRIO": 24.113698814046117, "ROTATEQ": 20.622532025437835, "SPIKEVAX": 3.4645391636429013}
\ No newline at end of file
+{"null": 3.216840619012}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4475.json
index 0f41715b695..8405c985227 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4475.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4475.json
@@ -1 +1 @@
-{"FENTANYL": 56.58658394473184, "LACOSAMIDE": 117.70002922557444}
\ No newline at end of file
+{"null": 1.2948793116345525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4476.json
index 281b06f7f75..efa9e3e2162 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4476.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4476.json
@@ -1 +1 @@
-{"null": 2.2968835216399444}
\ No newline at end of file
+{"COMIRNATY": 0.7453754390770845, "GARDASIL": 4.20169660850503, "SHINGRIX": 6.7641752795963805, "SPIKEVAX": 1.1680151669817678, "TOZINAMERAN": 1.7904307243359543, "null": 1.2598766243774997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4477.json
index 307eca9dcb5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4477.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4477.json
@@ -1 +1 @@
-{"BUDESONIDE": 2.7832979154744653, "BYDUREON": 99.47828675714672, "BYETTA": 19.66679124523517, "null": 5.910703605176792}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4478.json
index 3db575e907b..611dd3ac7f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4478.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4478.json
@@ -1 +1 @@
-{"null": 2.1447791014765603}
\ No newline at end of file
+{"COMIRNATY": 2.1493701382868378, "SPIKEVAX": 0.7890287415315941, "VAXZEVRIA": 1.5246377824935666, "null": 0.504483381097527}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4479.json
index f4a6d04f922..5822a54caa2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4479.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4479.json
@@ -1 +1 @@
-{"AUBAGIO": 1.8488139068738307, "BENLYSTA": 1.8086900634680003, "BIKTARVY": 6.3712044032950805, "CIMZIA": 12.84291335166854, "EPCLUSA": 41.02321788655625, "EVENITY": 6.336179286098685, "EYLEA": 2.999944850978076, "FAMPYRA": 4.250524260957696, "FORXIGA": 3.593928862141766, "HARVONI": 4.826400603707151, "HUMIRA": 4.108916592193777, "IBRANCE": 2.832569606483682, "INSULIN": 2.867989424634064, "JANUMET": 1.801932604359437, "LANTUS": 3.724648034225882, "LATUDA": 4.296082312664163, "LEVEMIR": 6.966707818988658, "MEPOLIZUMAB": 7.077536511994595, "REMSIMA": 161.68423900628736, "SAXENDA": 3.6304570118362287, "SOFOSBUVIR": 99.27973837023455, "TOUJEO": 8.955473371269257, "TRELEGY": 3.67426828525032, "VAXZEVRIA": 1.2005781698018516, "VICTOZA": 3.1675452057313227, "XELJANZ": 10.244864731010944, "XTANDI": 11.041481994955625, "null": 1.3503498505548217}
\ No newline at end of file
+{"COMIRNATY": 0.836217290864934, "SPIKEVAX": 1.5879530878457535, "null": 0.2942837640543819}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/448.json
index 53e4d4f8874..2b73efcd2e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/448.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/448.json
@@ -1 +1 @@
-{"CELLCEPT": 1.8490423858829692, "ENTYVIO": 7.912944950868469, "INCIVO": 47.329415359232186, "JARDIANCE": 1.6917307653727656, "NEXAVAR": 1.2186480293969275, "PEGASYS": 37.35516016730588, "PEGINTERFERON": 30.33917692142135, "PEGINTRON": 3.7577784435142942, "RIBAVIRIN": 6.377334237445123, "SUTENT": 4.3090965652021485, "null": 1.4983202105367115}
\ No newline at end of file
+{"COMIRNATY": 2.0888357176228958, "SPIKEVAX": 0.7890287415315941, "null": 0.871226574543269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4480.json
index 110ace6d05d..0618a691eb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4480.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4480.json
@@ -1 +1 @@
-{"null": 9.167961729456698}
\ No newline at end of file
+{"null": 0.8939870514157086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4481.json
index 5fef62c2a49..f9094ea6847 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4481.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4481.json
@@ -1 +1 @@
-{"ABILIFY": 3.772529946033434, "ACTRAPID": 1.90798578755888, "AERIUS": 1.8432938619763048, "ALL": 2.10938882077663, "ARIPIPRAZOLE": 2.745510753742048, "ASENAPINE": 8.797260050481878, "AXURA": 10.644863180880686, "BENZODIAZEPINE": 13.518373231367365, "BENZODIAZEPINES": 5.675225325817674, "BETA": 8.088083989614736, "BETADORM": 80.7833639710511, "BRINTELLIX": 2.5467565856706247, "BUPIVACAINE": 1.9779337929718612, "BUPRENORPHINE": 1.1824623988168184, "CHAMPIX": 1.1290939102847308, "CIRCADIN": 12.446035773319412, "CYMBALTA": 2.632084065356997, "DESLORATADINE": 4.923887587801009, "DULOXETINE": 5.329987568566059, "EMTRICITABINE": 1.0507283974199804, "ESOMEPRAZOLE": 12.269213907308025, "FYCOMPA": 6.698387422911089, "GENVOYA": 1.0162852036349783, "GLIBENCLAMIDE": 4.961168312689323, "GLUCAGON": 7.143546894706867, "GUANFACINE": 10.284906114126846, "HUMALOG": 1.0715660129804017, "HYDROCHLOROTHIAZIDE": 2.0235000204827176, "IBUPROFEN": 15.475397069824515, "INSULIN": 2.4416901290381143, "INVEGA": 10.229395938062794, "IRON": 1.4314954993282023, "KEPPRA": 1.960026738141214, "LACOSAMIDE": 1.99702080445486, "LANTUS": 1.5754029071895697, "LATUDA": 1.7682508959713277, "LEVETIRACETAM": 1.8773315236571944, "LEVODOPA": 2.1956543299060334, "LYRICA": 3.5011089666020343, "MELATONIN": 25.59099691240368, "MIDAZOLAM": 2.247905576431754, "NALOXONE": 2.196628648644798, "NOT": 1.4360679744795288, "NOVORAPID": 3.0614023831950026, "OLANZAPINE": 7.554817683992456, "OPIOIDS": 7.009035091167111, "OXYBUTYNIN": 2.7752177972143093, "PANTOPRAZOLE": 1.3650064145862282, "PERAMPANEL": 9.741663556189955, "PIOGLITAZONE": 5.9082427349603925, "PREGABALIN": 4.761976522278563, "PROPRANOLOL": 6.065148853864478, "RANOLAZINE": 1.535378770095508, "RISPERIDONE": 1.3123623405056632, "RIVAROXABAN": 7.056958957338947, "SIFROL": 1.3723968372153998, "SILDENAFIL": 1.0145753019720531, "SONATA": 36.05160301566608, "SUBOXONE": 1.0006857749717273, "SYCREST": 1.1830649347281106, "TELMISARTAN": 1.906931603417956, "TRESIBA": 5.235566304593297, "TRICYCLIC": 36.2364660944628, "UNKNOWN": 4.922599400571227, "UNSPECIFIED": 4.52359954519825, "VALDOXAN": 30.09070341614108, "VIAGRA": 1.8806834931199043, "VILDAGLIPTIN": 4.282044848885023, "VIMPAT": 1.2798212965827869, "ZALASTA": 17.66585940476954, "ZYPREXA": 7.941652174465774, "null": 6.257861830906898}
\ No newline at end of file
+{"COMIRNATY": 1.8880261194819012, "SPIKEVAX": 1.006918621005916, "TOZINAMERAN": 1.034472426239496, "VAXZEVRIA": 0.7594112680694042, "null": 1.0680142102275805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4482.json
index 44fff0e02b4..1786020114b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4482.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4482.json
@@ -1 +1 @@
-{"ABACAVIR": 15.989563109724989, "ALL": 2.113627040119439, "ANTIBIOTICS": 2.0501502427803837, "APIDRA": 2.351465915269948, "APIXABAN": 3.2768825125569387, "APROVEL": 1.1533661511679558, "ARANESP": 4.96069783902575, "ARIPIPRAZOLE": 3.1354624893195746, "BENZODIAZEPINE": 13.86563142128302, "BENZODIAZEPINES": 5.774684714109031, "BETMIGA": 2.4986282477666037, "BEVESPI": 14.79702221649479, "BORTEZOMIB": 1.9205047210425883, "BOSULIF": 1.796081580496752, "BRILIQUE": 1.7048921160662431, "BRIVIACT": 3.397187050680177, "BUPRENORPHINE": 9.582081594534106, "BYDUREON": 6.5403382336719655, "BYETTA": 1.921768621168593, "CANNABIDIOL": 1.0977056689579463, "CERTOLIZUMAB": 9.408359506921531, "CHAMPIX": 1.0620184948124498, "CIALIS": 2.09179562207739, "CYMBALTA": 2.6433800547004966, "DALIRESP": 8.952161062495813, "DAPTOMYCIN": 4.020798860586919, "DARBEPOETIN": 10.035865815699998, "DULOXETINE": 1.754387005282252, "FAMPYRA": 3.242388889528468, "FASENRA": 1.3367675358705255, "FASLODEX": 1.194970744206011, "FENTANYL": 6.378797461038319, "FIASP": 1.0192418270231398, "FORXIGA": 5.097934772386181, "GLIBENCLAMIDE": 1.807981064731327, "GUANFACINE": 11.072050637112987, "HUMALOG": 1.1797820661156384, "HYDROCORTISONE": 1.0025720640837663, "HYDROXOCOBALAMIN": 32.936759697651475, "IBUPROFEN": 3.105478247839591, "IKERVIS": 6.831764581064476, "INSULIN": 1.1314845247592085, "INVEGA": 2.4435521690193496, "KEPPRA": 1.834886763577828, "LANTUS": 1.6968680343950815, "LEVODOPA": 4.184631161899871, "LURASIDONE": 2.365366297291258, "LYNPARZA": 1.679390161777414, "LYRICA": 4.146299536315696, "MELATONIN": 4.24822352432333, "MIDAZOLAM": 4.460550945793516, "MIRABEGRON": 3.649053886918591, "MYCAMINE": 3.040676915460081, "NALOXONE": 2.365366297291258, "NOT": 1.260536844718181, "OLANZAPINE": 2.1397681211237107, "ONGLYZA": 4.727251592888439, "OTHER": 7.512509041822097, "PALIPERIDONE": 3.538349011329053, "PREGABALIN": 7.825524793513819, "QUTENZA": 1.6001308875429177, "RAPAMUNE": 1.875069708701508, "REVATIO": 1.81357096794818, "RINVOQ": 1.2505746337943866, "RISPERIDONE": 1.995397921631496, "SILDENAFIL": 2.088038196609052, "SKELETAL": 101.95006512172726, "SKYRIZI": 1.1417201065665707, "SOMATROPIN": 2.0170800566277776, "SUBOXONE": 6.23324655309875, "TESTOSTERONE": 3.0541380412068246, "TOUJEO": 3.832139251058136, "TOVIAZ": 2.1827080823906493, "TRESIBA": 1.0482705365836942, "UNKNOWN": 8.231470919708164, "UNSPECIFIED": 13.814003587134271, "VIAGRA": 8.308365312393084, "VIMPAT": 2.171438806846552, "XELJANZ": 4.37964386306572, "XYREM": 3.5747610497699687, "null": 3.517618132289173}
\ No newline at end of file
+{"null": 1.7675830304097986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4483.json
index c4b80164b13..92c5b056768 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4483.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4483.json
@@ -1 +1 @@
-{"null": 2.4699264535838386}
\ No newline at end of file
+{"COMIRNATY": 0.946261289375115, "DULOXETINE": 122.49291959124122, "null": 0.9899765831711672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4484.json
index 4e2b1db097d..4a4ea8e143b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4484.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4484.json
@@ -1 +1 @@
-{"ABACAVIR": 1.220508772544313, "ABATACEPT": 6.020497934137922, "ADALIMUMAB": 7.699286925355375, "ADCETRIS": 3.185199069056277, "ALEMTUZUMAB": 1.9186501117286017, "AMIKACIN": 3.1424090786547647, "AMINOSALICYLIC": 5.107189440060783, "ANAKINRA": 9.21850463348562, "APIXABAN": 6.589281735569899, "APREPITANT": 1.880426224372818, "ARAVA": 2.847906255774537, "ATAZANAVIR": 1.983664465221216, "ATEZOLIZUMAB": 3.18133767053616, "AVASTIN": 2.577616702989084, "AZACITIDINE": 1.5077986114783273, "BASILIXIMAB": 1.6841800050932076, "BEDAQUILINE": 15.63819680324032, "BENZODIAZEPINE": 3.349644179158676, "BIKTARVY": 1.134199261964224, "BORTEZOMIB": 2.995250424325476, "BUPRENORPHINE": 3.898457835824432, "CARFILZOMIB": 15.965461379054137, "CARMUSTINE": 3.608205769563999, "CELLCEPT": 8.537142438057458, "CHLORHEXIDINE": 3.7152225990909153, "CIMZIA": 2.0783979748450414, "COBIMETINIB": 2.4471090168077203, "COTELLIC": 8.626283045552423, "CRESEMBA": 5.304643833263192, "CYTARABINE": 1.5215386262373418, "DABRAFENIB": 2.141262215847849, "DARATUMUMAB": 2.985059149369655, "DARZALEX": 9.932199209606177, "DASATINIB": 2.5418357765786648, "DELAMANID": 13.289884381988626, "DEXAMETHASONE": 1.9233650708952676, "DEXMEDETOMIDINE": 4.518448539481129, "DOCETAXEL": 1.4620401649442518, "DOXORUBICIN": 1.8953315820187977, "EFAVIRENZ": 5.675337181040123, "ELIQUIS": 12.30260033786641, "ENBREL": 1.835505620536005, "ENTECAVIR": 1.813669698092513, "EPCLUSA": 3.967335430354284, "ESBRIET": 3.957210026587711, "ESMYA": 19.525537612815267, "FENTANYL": 1.250427602800116, "FIRDAPSE": 4.69041585991112, "GANCICLOVIR": 4.597188256118383, "GAZYVARO": 6.243268441841447, "GENVOYA": 1.4400897982670655, "HEMLIBRA": 3.748389255691916, "HERCEPTIN": 2.451642646884129, "HUMAN": 9.49510192876428, "HYQVIA": 2.0846086904484973, "INFLECTRA": 7.615369493215052, "INFLIXIMAB": 3.194968426746589, "IPILIMUMAB": 19.045617853119158, "JARDIANCE": 1.0300835339607164, "LENALIDOMIDE": 2.9335982464945336, "LONSURF": 6.709232006755912, "LUTATHERA": 4.972946445322618, "LYRICA": 1.2041090678075297, "MABTHERA": 4.341645693306297, "MELATONIN": 1.3227865809756372, "MYCOPHENOLATE": 1.600991339667195, "NIVOLUMAB": 15.92180494662868, "OBINUTUZUMAB": 3.3335878198901407, "OCREVUS": 7.445990178470172, "OPDIVO": 16.126217029358234, "PACLITAXEL": 1.1082123231153664, "REAGILA": 9.950928045305458, "REMDESIVIR": 2.639631552368108, "REMSIMA": 9.529521865024185, "REVATIO": 1.8684889727619645, "RIBAVIRIN": 1.0300138130195322, "RITUXIMAB": 3.1498801228938698, "ROACTEMRA": 10.91746812994703, "RUCONEST": 67.23278723665948, "SIRTURO": 20.168822450481315, "SPRYCEL": 4.0174721438645, "SUBOXONE": 5.534120197679731, "TAMIFLU": 1.1695938928445628, "THALIDOMIDE": 1.049819047333919, "TOCILIZUMAB": 19.627492512694943, "TOUJEO": 4.008458175524142, "TOVIAZ": 1.9375481281811564, "UROREC": 3.586827280680069, "VENETOCLAX": 2.4442210024458744, "VIAGRA": 3.238322798031636, "XELJANZ": 2.154031897911602, "XELODA": 2.107817980361163, "XTANDI": 1.2342587834458356, "XYREM": 3.297483072452432, "YERVOY": 3.471437852717989, "ZELBORAF": 6.163320274795139, "null": 1.0744170857167148}
\ No newline at end of file
+{"COMIRNATY": 8.106789159052836}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4485.json
index 7e45140b9f4..3ef2125be12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4485.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4485.json
@@ -1 +1 @@
-{"null": 4.388694975075853}
\ No newline at end of file
+{"AFINITOR": 2.232784519607994, "ALIMTA": 2.545970090401545, "AMIKACIN": 1.9483154107511365, "ARANESP": 0.5622362086709904, "AVAMYS": 0.7126730478219585, "BETMIGA": 7.685191081438687, "BRIDION": 13.404843000973436, "BUDESONIDE": 0.2679500314723838, "CHAMPIX": 0.7977209868761449, "CICLOSPORIN": 0.3877190856012044, "CIMZIA": 0.2145902944067068, "COAPROVEL": 1.923779562867607, "COMIRNATY": 0.8616355123179321, "COSENTYX": 0.4684025570619803, "ELIQUIS": 0.1722332882514049, "ENTRESTO": 0.7237880083952566, "EVEROLIMUS": 3.2907684808401663, "EXFORGE": 1.657589130814371, "EXJADE": 0.5028255985771711, "EYLEA": 1.2336666790242692, "FASENRA": 0.8916619780879981, "FORSTEO": 0.4225967716846358, "GARDASIL": 0.9817536325042368, "GLIVEC": 7.052587376183572, "HYDROCORTISONE": 1.0603963035704052, "IBUPROFEN": 0.9221239768508273, "KEPPRA": 0.2068957947262713, "LANTUS": 0.1770808035470054, "LEVOFLOXACIN": 1.7868568132956275, "MMRVAXPRO": 1.8929433444839268, "MODERNA": 1.8363761198739368, "NEVANAC": 8.951055236548877, "NEXAVAR": 0.4978971554784286, "NORVIR": 4.209716842282538, "OLANZAPINE": 0.4033483118855998, "ONCASPAR": 9.766366263828298, "PEGASYS": 0.3759774489823482, "PEGINTRON": 0.3211467823330411, "PEMETREXED": 5.943825526776097, "PLAVIX": 0.3430766881692041, "RASILEZ": 2.5551337913991423, "RINVOQ": 0.735874191066711, "ROACTEMRA": 1.4936415809041148, "SIMPONI": 0.3646143638230121, "SPIKEVAX": 0.3346012964401685, "SUTENT": 2.0434233132144115, "TASIGNA": 0.7683016580343366, "TOBRAMYCIN": 5.160497237279721, "TOPOTECAN": 23.55041516799586, "TOZINAMERAN": 0.259901620313777, "VAXZEVRIA": 0.3012663597223276, "XOLAIR": 1.3324824888717317, "ZYPREXA": 0.8092224489592599, "null": 2.850358768823301}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4486.json
index b76f0447c1e..66b69631af1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4486.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4486.json
@@ -1 +1 @@
-{"ABILIFY": 5.965053291818346, "ARIPIPRAZOLE": 4.344609136199009, "BRINTELLIX": 5.136491299394668, "BRIVIACT": 2.650526862832382, "BUPRENORPHINE": 2.683340069917237, "CHAMPIX": 3.650554367449632, "CIRCADIN": 30.720896867071737, "CYMBALTA": 2.070111754560939, "DESLORATADINE": 8.434215511454896, "DULOXETINE": 8.799847906756787, "IBUPROFEN": 1.7260074276024122, "IVABRADINE": 17.022503347519358, "KAFTRIO": 4.271506978235504, "KEPPRA": 2.0498707183864022, "LACOSAMIDE": 2.473835428227112, "LATUDA": 8.39948755539375, "LYRICA": 3.4504393299099734, "MELATONIN": 106.75947978058886, "OLANZAPINE": 7.8334947877281875, "OXYBUTYNIN": 3.4815148195146457, "PREGABALIN": 4.461698494727343, "TAMIFLU": 1.5741037628121133, "ZYPREXA": 3.0418204352096465, "null": 6.770219572095157}
\ No newline at end of file
+{"null": 1.1852302252440632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4487.json
index 04e5c7a4f47..0dd1eeb00fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4487.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4487.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 33.65582974033644, "ELIQUIS": 3.2489984699311987, "FAMPYRA": 17.65374674703969, "FENTANYL": 2.8870371784719087, "INCRUSE": 10.543246415066337, "RUBRACA": 12.42558380467375, "SUBOXONE": 213.1942893543241, "XELJANZ": 1.5252767724162164, "XTANDI": 17.542703145611828, "null": 1.2410517384706894}
\ No newline at end of file
+{"COMIRNATY": 1.8402591082296065, "SPIKEVAX": 0.7507582359822476, "SUTENT": 2.306369514102645, "TOZINAMERAN": 2.597665550985389, "VAXZEVRIA": 1.510818451954424, "null": 0.5590468596230825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4488.json
index fc1a6425050..75c44d75354 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4488.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4488.json
@@ -1 +1 @@
-{"INCRUSE": 73.12638411309189, "LANTUS": 8.892152665791771, "null": 1.1757414685484784}
\ No newline at end of file
+{"ABACAVIR": 22.46328883559437, "ABILIFY": 1.5186604060741329, "ATAZANAVIR": 24.27989063167037, "CHAMPIX": 0.7210448002672635, "CICLOSPORIN": 0.7715922786801394, "COMIRNATY": 0.7383906835952357, "CRIXIVAN": 31.305880577446903, "CYMBALTA": 0.3613178694800153, "DEXAMETHASONE": 0.8453035824091358, "ELIQUIS": 0.4452656764639323, "ENFUVIRTIDE": 108.78052370969765, "FENTANYL": 1.825738783560512, "GARDASIL": 1.1394323432554825, "KALETRA": 2.818267765747361, "KEYTRUDA": 6.5228979283145625, "METHOTREXATE": 1.002137445907998, "OPDIVO": 5.760881421450782, "PEGASYS": 0.3182939184008753, "PEGINTRON": 1.1733931547813388, "PEMBROLIZUMAB": 4.886720248597092, "SAQUINAVIR": 300.42700844247446, "SHINGRIX": 1.2970571226124428, "SOLIRIS": 2.856473011776091, "SPIKEVAX": 0.5420671961858643, "SUTENT": 0.2446175471504885, "TOPOTECAN": 32.60504106935826, "TOZINAMERAN": 1.3750170177609142, "VAXZEVRIA": 0.43523244225671, "XOLAIR": 1.0672572922191448, "ZOSTAVAX": 3.3403628649891, "ZYPREXA": 0.6536279106453975, "null": 0.9337426456161484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4489.json
index 96c4ca98ecb..d78f8c65863 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4489.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4489.json
@@ -1 +1 @@
-{"AIMOVIG": 24.72587207117854, "ESMYA": 478.3268084470686, "null": 1.827782275796406}
\ No newline at end of file
+{"null": 3.107579688344918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/449.json
index f2d532604d0..e71f880f737 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/449.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/449.json
@@ -1 +1 @@
-{"ENTYVIO": 12.5020718549913, "INCIVO": 69.15428657856077, "PEGASYS": 5.565616156234569, "PEGINTERFERON": 8.284601741361508, "RIBAVIRIN": 9.232428133105154, "STELARA": 3.557080651784194, "SUTENT": 5.018349112826401, "XELJANZ": 2.31115344831101, "null": 1.3106021787900035}
\ No newline at end of file
+{"ADALIMUMAB": 5.555172140707873, "ARAVA": 6.724946439195117, "COMIRNATY": 0.3651411169151409, "OMALIZUMAB": 28.603803712803877, "TOZINAMERAN": 1.119180369361457, "null": 0.8025680385051017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4490.json
index 49b2e545815..779e277ee5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4490.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4490.json
@@ -1 +1 @@
-{"HUMALOG": 52.15020285167839, "null": 1.7602521017145338}
\ No newline at end of file
+{"COMIRNATY": 1.059929282075032, "SPIKEVAX": 0.6374095769926913, "TOZINAMERAN": 1.7469517254905014, "VAXZEVRIA": 1.167421577681297, "null": 0.5760012192663719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4491.json
index 342e0d13258..f39453df4bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4491.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4491.json
@@ -1 +1 @@
-{"CIMZIA": 6.133378396493077, "LONSURF": 50.29835026126475, "METFORMIN": 103.4576834254992, "null": 2.2517713372367423}
\ No newline at end of file
+{"null": 0.6470135058058539}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4492.json
index 70cdc07d26d..bca597ba29a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4492.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4492.json
@@ -1 +1 @@
-{"HUMALOG": 104.3391302207189}
\ No newline at end of file
+{"COMIRNATY": 1.435041271324074, "null": 1.0444346438651106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4493.json
index 35018025abb..d6f1532ed4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4493.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4493.json
@@ -1 +1 @@
-{"PEGASYS": 35.60219331159884, "ROACTEMRA": 91.2333790269778}
\ No newline at end of file
+{"null": 0.3793055732831707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4494.json
index 2ce4c8605cf..e1b6214abb6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4494.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4494.json
@@ -1 +1 @@
-{"CERVARIX": 5.423395614628828, "COMIRNATY": 21.00655705913473, "ELASOMERAN": 31.434959645299845, "GARDASIL": 1.32736847753414, "JCOVDEN": 9.584459182728647, "SPIKEVAX": 2.5343236687583945, "TOZINAMERAN": 1.4367504957387471}
\ No newline at end of file
+{"COMIRNATY": 0.6532265494750573, "null": 0.7280973806202069}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4495.json
index 217772ff763..883fee298c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4495.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4495.json
@@ -1 +1 @@
-{"COMIRNATY": 2.692380184403124}
\ No newline at end of file
+{"COMIRNATY": 0.9010314822408924, "SPIKEVAX": 0.772542093171784, "TOZINAMERAN": 2.224330633051527, "VAXZEVRIA": 0.4029183871052539, "null": 1.555511515208947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4496.json
index 2d988f98244..c355b1efe76 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4496.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4496.json
@@ -1 +1 @@
-{"COMIRNATY": 4.287974352894451}
\ No newline at end of file
+{"ESOMEPRAZOLE": 464.2497912425585, "null": 0.5899625428937079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4497.json
index 3e61b4c460c..3313b62e05d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4497.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4497.json
@@ -1 +1 @@
-{"ARAVA": 16.758174057839074}
\ No newline at end of file
+{"MEPOLIZUMAB": 50.49218562455997, "OMALIZUMAB": 270.00714613289904, "XOLAIR": 74.0900143252954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4498.json
index a6e3e065547..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4498.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4498.json
@@ -1 +1 @@
-{"COMIRNATY": 5.33278085778676}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4499.json
index 1513d1104c8..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4499.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4499.json
@@ -1 +1 @@
-{"ANAKINRA": 106.50186381140963, "KYMRIAH": 125.56499856297658, "ROACTEMRA": 38.13758660722405}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/45.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/45.json
index 1c3c78a0a9a..56c98073551 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/45.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/45.json
@@ -1 +1 @@
-{"ABILIFY": 1.494269655322639, "ACTRAPID": 7.237452877445067, "ALISKIREN": 7.844961259580289, "ATAZANAVIR": 4.153367745355752, "AUBAGIO": 1.5668208225747788, "BARACLUDE": 27.71601358098749, "BIKTARVY": 4.250644590181727, "BUPRENORPHINE": 1.52326058677427, "CELLCEPT": 1.2334063585862167, "CIMZIA": 1.1870054651876325, "COMBIVIR": 20.807068118388536, "DARUNAVIR": 8.606587403070778, "EFAVIRENZ": 5.908968048573806, "ELLAONE": 131.69229441514122, "ENOXAPARIN": 2.8466405482711528, "EPIVIR": 5.778234555351153, "FENTANYL": 4.2071146256265815, "GARDASIL": 11.804580931956572, "GENVOYA": 15.898322827889846, "INTRONA": 12.54486533736513, "ISENTRESS": 9.162201457621572, "KAFTRIO": 5.159001697457107, "KALETRA": 12.279363035061952, "KEPPRA": 6.113819021648333, "LAMIVUDINE": 7.052488303638123, "LEVEMIR": 1.790468112898074, "LEVETIRACETAM": 3.8912446113691455, "MIDAZOLAM": 2.3308733405785, "PEGASYS": 1.8055764894950688, "PEGINTRON": 7.867377124620278, "REBETOL": 7.991108066830665, "RINVOQ": 2.4732068224866106, "STOCRIN": 55.492594492243846, "SUBOXONE": 10.19443815588424, "TRACLEER": 6.086982017000009, "VICTOZA": 2.269932421426158, "VIMPAT": 4.636131950338319, "null": 1.6699680483307466}
\ No newline at end of file
+{"null": 3.560072764387048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/450.json
index f41c56971b8..bd77a421a47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/450.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/450.json
@@ -1 +1 @@
-{"null": 1.3676015331365603}
\ No newline at end of file
+{"COMIRNATY": 0.1377820515778794, "HEXYON": 610.2763127030163, "INFANRIX": 68.33082693779392, "MMRVAXPRO": 126.83694354529229, "OMALIZUMAB": 10.358844368220575, "PREVENAR": 103.3298867341244, "TWINRIX": 31.208132785762515, "null": 0.5240055526199799}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4500.json
index 01dcd307b91..ace6894b5bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4500.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4500.json
@@ -1 +1 @@
-{"COMIRNATY": 11.099753728844435, "ELLAONE": 6.011288323229672, "ESMYA": 5.503489464216597, "EVRA": 13.32914071501503, "RYEQO": 25.013564563326437, "SPIKEVAX": 2.435020914600985, "SPIRONOLACTONE": 1.0895979706286074, "TOZINAMERAN": 1.1451063383922813}
\ No newline at end of file
+{"BIKTARVY": 7.775094238083694, "COMIRNATY": 0.2705007281930284, "CYMBALTA": 1.3140192904990022, "ELIQUIS": 2.1289189821017565, "GARDASIL": 4.792482205430915, "HUMALOG": 2.2147884157372757, "KEPPRA": 4.789289008738435, "LANTUS": 1.9551149268670256, "SPIKEVAX": 0.6779021028194779, "SUTENT": 1.4550226479694066, "TOZINAMERAN": 1.2802536945405576, "VAXZEVRIA": 0.1221042499970407, "null": 1.1122105043127837}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4501.json
index d917300e26c..d1451ecdd12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4501.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4501.json
@@ -1 +1 @@
-{"CICLOSPORIN": 2.001356559354298, "CLOPIDOGREL": 4.1878062640327816, "ICLUSIG": 18.31691825185636, "NILOTINIB": 154.9842544643605, "ROACTEMRA": 5.844934264630948, "TASIGNA": 138.1047019969824, "ZOSTAVAX": 5.160099673135114}
\ No newline at end of file
+{"AERIUS": 2.8084643895895427, "AFINITOR": 1.2196012572723296, "AIMOVIG": 0.1468100603021794, "ALDARA": 1.8438180722275457, "ALIMTA": 1.4458989216827651, "APIDRA": 0.3951670996402296, "APROVEL": 2.664268242226385, "ARANESP": 0.2963374959173042, "ASPARAGINASE": 1.388689206275039, "ATAZANAVIR": 1.6457388266911084, "ATRIPLA": 0.0485265631074746, "AVAMYS": 0.4758948550663761, "AVANDIA": 0.3591312875848069, "AVAPRITINIB": 43.97098945438533, "AVASTIN": 0.3680139474710187, "BENLYSTA": 0.6746113951598844, "BETMIGA": 1.278849093142079, "BIKTARVY": 0.499715398933877, "BINOCRIT": 8.155972602707898, "BONVIVA": 1.6074002987426843, "BRIDION": 2.4530694055438267, "BRILIQUE": 0.6824377665927309, "BRINTELLIX": 0.2308594597166653, "BUDESONIDE": 1.0271511742091832, "BYDUREON": 0.235757775713902, "CAELYX": 1.2342639430281734, "CANCIDAS": 1.3931982122728437, "CELECOXIB": 0.7295248771265365, "CELLCEPT": 0.5899281848447165, "CHAMPIX": 0.8248086544951235, "CHLORHEXIDINE": 0.6756472624153446, "CICLOSPORIN": 0.2756623321632194, "CIMZIA": 0.2305821869705042, "CLOPIDOGREL": 0.350212288155687, "COAPROVEL": 1.9831426710629023, "COMBIVIR": 1.3495383456229264, "COMIRNATY": 0.6539390888470495, "COSENTYX": 0.4687154032344984, "COTELLIC": 6.139019589925036, "CUBICIN": 0.656349258307423, "CYTARABINE": 0.2223821920144313, "DESLORATADINE": 2.386858346690652, "DEXAMETHASONE": 0.7527453475860011, "DOCETAXEL": 0.418063007254625, "ELIQUIS": 0.2736626097407786, "EMEND": 1.7369561385129793, "EMTRICITABINE": 1.3020454097424288, "ENTRESTO": 0.921853063114333, "ENTYVIO": 0.2546599297565127, "ESBRIET": 0.4843927597425002, "ESOMEPRAZOLE": 0.7713284246467861, "EUCREAS": 1.5856294711790984, "EXFORGE": 3.1845933534942628, "EXJADE": 0.4056680298307507, "FASENRA": 0.9269340651952852, "FASLODEX": 0.2429047291330022, "FENTANYL": 0.6539806299408367, "FORSTEO": 0.8352357187834952, "FORXIGA": 0.3004832307840801, "GALVUS": 2.0411462221419048, "GARDASIL": 0.4736548972885431, "GLIVEC": 4.190474902876286, "HARVONI": 0.5185956670734988, "HUMALOG": 0.0920031436001664, "IBRANCE": 0.0850532509343508, "IBUPROFEN": 1.0934807908204045, "IMATINIB": 1.543547182926858, "INCIVO": 4.428952767510319, "INSULIN": 0.6881526699509177, "INTRONA": 1.135069512512093, "ISENTRESS": 1.509547173569878, "JANUMET": 0.2357346249748715, "JANUVIA": 0.5320664246153848, "JARDIANCE": 0.3662058412964895, "KALETRA": 0.7095828823186077, "KEPPRA": 0.5465774955080503, "KEYTRUDA": 0.4031467565923783, "KISQALI": 0.6776664296711636, "KYMRIAH": 1.0483636077563163, "LAMIVUDINE": 0.9694847968812152, "LANTUS": 0.1189820471538227, "LEVEMIR": 0.4979214408720519, "LEVETIRACETAM": 0.7604449198098429, "LEVOFLOXACIN": 2.33563398750285, "LYNPARZA": 0.6674912783911305, "LYRICA": 1.4419510601356134, "MEKINIST": 0.7300303809270465, "MICARDIS": 2.6661602853325848, "MIDAZOLAM": 0.6032929904640547, "MMRVAXPRO": 0.5547612998614165, "MODERNA": 1.3634966558754291, "NEULASTA": 0.7215598642113952, "NEXAVAR": 0.7971931237590195, "NIMENRIX": 0.5950597094912121, "NORVIR": 1.5751248189126166, "NOT": 0.7076116213396443, "NOXAFIL": 1.1307696985968765, "NUCALA": 0.5355343245123119, "OLANZAPINE": 0.4288871566199682, "OMALIZUMAB": 0.26388159244703, "ONCASPAR": 6.828729344336477, "OPDIVO": 0.2505540486323833, "OPSUMIT": 0.3783668746996205, "PEGASYS": 0.77782645757088, "PEGINTERFERON": 1.5336477518160738, "PEGINTRON": 1.262158159572213, "PLAVIX": 0.6961322226091899, "PREGABALIN": 0.5004396741245143, "PRIVIGEN": 0.4991244416769198, "PROTELOS": 4.124734742946936, "RASILEZ": 6.311605107907201, "RELVAR": 1.6231386884769523, "RINVOQ": 0.6264307953895373, "ROACTEMRA": 1.9896090270261777, "SHINGRIX": 0.1991828648793255, "SIMPONI": 0.2629129254773925, "SOLIRIS": 0.2060703785096031, "SPIKEVAX": 0.2892051167741304, "SPRYCEL": 1.2328678911713575, "STELARA": 0.3569909399339403, "STIVARGA": 0.5911781927282482, "SUFENTANIL": 1.3638685808100464, "SUTENT": 1.5477411610667575, "TAMIFLU": 1.482281001813918, "TASIGNA": 0.8255839815979773, "TELMISARTAN": 1.7476248168748358, "TORISEL": 1.2656498356839978, "TOVIAZ": 0.8923258997824847, "TOZINAMERAN": 0.1333338531852831, "TRACLEER": 0.4576222551043821, "TREMFYA": 0.9905988169701312, "TRUVADA": 0.066929259891762, "TWINRIX": 0.8680375611358752, "VALSARTAN": 1.943384676387828, "VAXZEVRIA": 0.2592324925589168, "VFEND": 0.8708805289289373, "XALKORI": 0.7208554482661113, "XARELTO": 0.5490791825654762, "XOLAIR": 1.106702046453887, "XTANDI": 0.2915254811056751, "ZARZIO": 6.011509277355587, "ZELBORAF": 3.707722710651326, "ZYPREXA": 0.7506546017852733, "null": 3.081565268486751}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4502.json
index 8920db739a5..12a94b8b227 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4502.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4502.json
@@ -1 +1 @@
-{"null": 2.589912226151715}
\ No newline at end of file
+{"BENLYSTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4503.json
index 2b5a27f82f2..ff52ea694ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4503.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4503.json
@@ -1 +1 @@
-{"null": 1.8712994194553247}
\ No newline at end of file
+{"ABATACEPT": 50.98486852091079, "ADALIMUMAB": 88.47757471784507, "APREMILAST": 44.73696129518514, "APREPITANT": 9.568040256098945, "ARAVA": 7.414049638445824, "ATRIPLA": 1.190959682505506, "CIMZIA": 3.2543189072526446, "COMIRNATY": 0.0195523109415023, "COSENTYX": 3.219111597588294, "RITUXIMAB": 2.185241450283601, "TRUVADA": 0.5827120581792347, "ZOSTAVAX": 1.812760940015798, "null": 0.030896925404689}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4504.json
index 91de0d40f80..ef53fcf78aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4504.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4504.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 2.707054022941178, "ELIQUIS": 35.661988071516724, "ENTRESTO": 1.5130441385536642, "ESBRIET": 1.6340596982868263, "INLYTA": 1.6250887934849598, "LEVOFLOXACIN": 1.1677974464419958, "MACITENTAN": 31.748197089288187, "OPSUMIT": 3.5998042139603865, "PLAVIX": 22.00420456040948, "REVATIO": 3.902707183862157, "SPRYCEL": 4.193435703955299, "SUTENT": 2.5777776666964924, "TRELEGY": 3.2368065936582027, "VOTRIENT": 3.032973709693985, "XARELTO": 91.2080853710169, "XELJANZ": 1.2953337839602228, "XTANDI": 1.082902870503242}
\ No newline at end of file
+{"COMIRNATY": 1.9829984482694905, "SPIKEVAX": 0.5820176024746494, "SUBOXONE": 6.60045239718795, "TOZINAMERAN": 1.065745580708216, "VAXZEVRIA": 1.1216562556572984, "null": 0.6191334819853107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4505.json
index 16c88cbc422..3df42c04237 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4505.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4505.json
@@ -1 +1 @@
-{"null": 2.0381992078055684}
\ No newline at end of file
+{"COMIRNATY": 3.495906665601197, "NUCALA": 5.500505723368943, "SPIKEVAX": 2.032793693090156, "TOZINAMERAN": 3.7105819366293176, "VAXZEVRIA": 1.8036041758106065, "null": 0.1524752376084115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4506.json
index 0a1054e166a..0d898de6f15 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4506.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4506.json
@@ -1 +1 @@
-{"null": 2.154232826945312}
\ No newline at end of file
+{"COMIRNATY": 6.250018862477208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4507.json
index 6a62ac1dc0c..895378f8170 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4507.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4507.json
@@ -1 +1 @@
-{"null": 3.71029999959756}
\ No newline at end of file
+{"COMIRNATY": 2.323615871552947, "SPIKEVAX": 0.8803861622829738, "TOZINAMERAN": 1.900678294006292, "VAXZEVRIA": 0.982641856104478, "null": 0.4512169552826883}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4508.json
index 7c72de4d426..ffed2e44063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4508.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4508.json
@@ -1 +1 @@
-{"ABILIFY": 6.730385310330717, "ADENURIC": 47.30346194139375, "ELIQUIS": 3.566632118801942, "ENTRESTO": 2.113247653499666, "MULTAQ": 8.62087862811712, "PLAVIX": 2.389411160153802, "VIAGRA": 2.836846714200943, "XTANDI": 1.7351346733694053, "null": 4.05104163212557}
\ No newline at end of file
+{"null": 0.8953782293383834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4509.json
index d682e55b599..025ce8c0461 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4509.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4509.json
@@ -1 +1 @@
-{"BRILIQUE": 3.1884337624615133, "ENOXAPARIN": 4.369744797752236, "ENTRESTO": 1.6829889292526867, "ESBRIET": 7.824526782903493, "LYRICA": 1.6076595103670643, "MULTAQ": 4.887511920054617, "OZEMPIC": 19.860008161700613, "PLAVIX": 2.622995884057844, "ROACTEMRA": 2.2931311523347, "SOLIRIS": 2.1764887078622754, "TRACLEER": 4.734810183627554, "XTANDI": 2.6843084356349656, "null": 4.29020541406559}
\ No newline at end of file
+{"AIMOVIG": 0.6769868502430122, "APIXABAN": 31.0895401273248, "AUBAGIO": 1.3467905972971232, "AVAMYS": 1.7329278155849055, "BENLYSTA": 1.8964620868092412, "CICLOSPORIN": 0.4706506000895796, "COMIRNATY": 1.8932058905251423, "COSENTYX": 0.6814473959045945, "CYMBALTA": 0.4826750930040278, "DULOXETINE": 1.525902404603256, "ENBREL": 1.183457875975972, "EYLEA": 1.5983979732419369, "FAMPYRA": 6.99451675737047, "GARDASIL": 1.327331143118217, "HUMIRA": 0.856204547757223, "IBRANCE": 0.4345170359584523, "IBUPROFEN": 0.9029623797634184, "KEPPRA": 0.4133140720746074, "OCRELIZUMAB": 2.1275370874352078, "OPSUMIT": 0.727123585510923, "SHINGRIX": 4.522481011114067, "SPIKEVAX": 1.1911758051725398, "SUTENT": 0.2991383268701563, "TOZINAMERAN": 3.602684153660225, "TWINRIX": 2.251261880065717, "VAXZEVRIA": 1.3794142874926545, "VFEND": 1.3509411031588117, "XELJANZ": 0.5655320878996868, "XOLAIR": 0.5876070813944797, "ZOSTAVAX": 3.560449399099201, "null": 0.5162194746967315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/451.json
index 8380eef995c..0a8e8f1f684 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/451.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/451.json
@@ -1 +1 @@
-{"GARDASIL": 10.72942061592284, "null": 1.5689242432849575}
\ No newline at end of file
+{"OMALIZUMAB": 169.26475945914396, "null": 0.7252683840760221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4510.json
index 155cbd7b947..34ce00c9f1c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4510.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4510.json
@@ -1 +1 @@
-{"ARAVA": 1.659195206373523, "ELIQUIS": 3.6049734275225735, "ENTRESTO": 5.142195874885386, "KEPPRA": 1.2737243784438632, "PLAVIX": 3.312278737729205, "null": 6.017369906330414}
\ No newline at end of file
+{"ABACAVIR": 0.2033926600706504, "AFINITOR": 0.2102556142752136, "AIMOVIG": 0.3743338495042904, "AMIKACIN": 1.0951138113265382, "ARAVA": 0.0669864694172846, "AVANDIA": 0.1958255602263071, "BRAFTOVI": 1.2605118801740351, "BYETTA": 0.3284488387280906, "CANCIDAS": 1.6157271709073264, "CANNABIDIOL": 6.029554301778748, "CELECOXIB": 1.3282574894650567, "CELLCEPT": 0.2944153699281403, "CHAMPIX": 0.9169494340274924, "CICLOSPORIN": 0.4300795403764638, "CIMZIA": 0.2145882557738665, "CLOPIDOGREL": 0.4352928643288138, "COMIRNATY": 3.6210549583166114, "COSENTYX": 0.4321952133517917, "CYMBALTA": 0.2168275580723094, "CYTARABINE": 0.9942567325835656, "DEXAMETHASONE": 0.368247005205862, "ELIQUIS": 0.355241618557744, "ENTYVIO": 0.3741179330116535, "ESOMEPRAZOLE": 4.41383940769813, "EXFORGE": 0.7529942943417834, "EYLEA": 0.6310907197020775, "FAMPYRA": 0.806781919308948, "FASENRA": 0.5011874825227481, "FASLODEX": 0.574416438588519, "FENTANYL": 0.2297942591795561, "GARDASIL": 2.1577155711032687, "HARVONI": 0.5942603431024437, "HUMALOG": 0.1625144394896593, "HUMIRA": 0.4155227446480372, "IBRANCE": 0.2327367011208592, "ICLUSIG": 0.9858222440584614, "INTRONA": 2.0666796156607155, "IPILIMUMAB": 1.9626721413345556, "KEPPRA": 0.3830869090758502, "KEYTRUDA": 0.5689569258213041, "KYMRIAH": 0.9051242057605886, "LANTUS": 0.4046117843794426, "LATUDA": 0.7422799195431073, "LEVETIRACETAM": 0.2631183432951949, "MEKINIST": 0.5733758256131793, "MENVEO": 1.6117680859272194, "METHOTREXATE": 0.3260242551208839, "MMRVAXPRO": 0.4220283249509011, "MODERNA": 2.4609955054033974, "NEXAVAR": 0.2366130603627175, "OLANZAPINE": 0.249006976004743, "OPDIVO": 1.3193914969317322, "PEGASYS": 0.8179665097776445, "PEGINTERFERON": 0.5214406250492079, "PEGINTRON": 2.5092059960530646, "PLAVIX": 0.2819019835293844, "REBETOL": 2.117406766195512, "RINVOQ": 0.4136219099590951, "ROACTEMRA": 0.7373475931250659, "SHINGRIX": 2.89698346642293, "SOLIRIS": 0.2673687208891002, "SPIKEVAX": 1.8653898461488416, "STELARA": 0.8682887492122142, "SUTENT": 0.2193107238542041, "TASIGNA": 1.5951714183017422, "TOZINAMERAN": 3.2161340907459475, "TWINRIX": 1.6928434670205226, "VAXZEVRIA": 0.9623252014878728, "XELJANZ": 0.1580044752073575, "XOLAIR": 0.4948348322075206, "XTANDI": 0.1924929064428751, "ZOSTAVAX": 1.5718678896939484, "null": 0.414614307314944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4511.json
index b9edd389bf9..26856d19567 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4511.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4511.json
@@ -1 +1 @@
-{"ADEMPAS": 1.476325543437823, "ANGIOX": 11.86043449487409, "ARIXTRA": 4.262828652879841, "BUMETANIDE": 8.493334721022391, "CLOPIDOGREL": 1.7224211855613785, "CUBICIN": 2.549046171444755, "DASATINIB": 2.079905076942145, "ELIQUIS": 1.5719677995471748, "ENOXAPARIN": 5.5782886832393945, "ERBITUX": 1.5391492615854327, "EXVIERA": 2.911021979853384, "IBUPROFEN": 1.3179204518362395, "KALETRA": 1.638390999459826, "KETEK": 14.554849425650922, "KYMRIAH": 1.1576968427870478, "LEVOFLOXACIN": 3.105523449470476, "LIXIANA": 2.9090200625299394, "MEMANTINE": 2.9070948684615576, "MULTAQ": 14.238108353615944, "OSELTAMIVIR": 11.203657936697203, "PANTOPRAZOLE": 1.3766772142294184, "PLAVIX": 3.953282338771351, "PRADAXA": 6.653260931743654, "RAPAMUNE": 1.2512683843198429, "REMDESIVIR": 5.873059800814072, "REMICADE": 1.3447701900794542, "REVLIMID": 1.6394006097829448, "RIVAROXABAN": 4.366425158860022, "SORAFENIB": 2.1038195462158686, "TAMIFLU": 5.235228137226186, "TARCEVA": 8.283980724673425, "TRACLEER": 2.111860339399548, "VORICONAZOLE": 1.070414310274285, "XARELTO": 9.560471500323258, "XELEVIA": 23.44174657935997, "XELODA": 4.347527932144155, "XENICAL": 19.50159743590104, "null": 7.635049036833043}
\ No newline at end of file
+{"BRILIQUE": 2.137819432729089, "CHAMPIX": 0.4262096382475497, "COMIRNATY": 4.720039472957906, "ELIQUIS": 0.8468330619127142, "GARDASIL": 3.676057971027796, "MMRVAXPRO": 0.7102410173108115, "ROACTEMRA": 1.6901556785624563, "SHINGRIX": 2.712335720163058, "SPIKEVAX": 1.7660623728095055, "STELARA": 0.8522608519621496, "TOZINAMERAN": 1.1272694690522775, "TWINRIX": 15.845972085007704, "VAXZEVRIA": 1.3229987267589214, "ZOSTAVAX": 0.5146534671819197, "null": 0.3219739920604607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4512.json
index 2af93ecf5b8..ca123352c2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4512.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4512.json
@@ -1 +1 @@
-{"null": 2.738922347820625}
\ No newline at end of file
+{"COMIRNATY": 0.7430787585834953, "CYMBALTA": 5.818827609831024, "GARDASIL": 3.958420548822129, "SPIKEVAX": 0.5877595286485866, "TOZINAMERAN": 3.522918539104447, "VAXZEVRIA": 0.8884488244668299, "null": 1.0348698463043926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4513.json
index d1be1926e32..6db46a4868f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4513.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4513.json
@@ -1 +1 @@
-{"null": 1.7112874231168382}
\ No newline at end of file
+{"ABACAVIR": 31.997446216782944, "EPIVIR": 197.20698136397948, "null": 0.3131477852903752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4514.json
index e4456a79f86..e36ac4c095e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4514.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4514.json
@@ -1 +1 @@
-{"ABRAXANE": 10.92154847537796, "ACTOS": 2.4141536791469664, "ADCETRIS": 3.065816015355953, "ADCIRCA": 2.3807064037286896, "ADENURIC": 1.1136763674622796, "AFINITOR": 18.38645350175561, "ALECENSA": 19.73846127964552, "ALIMTA": 15.30992891974501, "ALL": 1.437288589496275, "ALOXI": 6.442653242552805, "ALPELISIB": 1.4406786922692931, "ANAKINRA": 5.930703949589351, "APROVEL": 1.881383685851965, "AVASTIN": 8.255300122299978, "AXITINIB": 1.630830687318955, "AZATHIOPRINE": 2.4908487113778346, "BARACLUDE": 1.36750612188959, "BAVENCIO": 1.4671679540837483, "BEVACIZUMAB": 2.3784154819380974, "BRAFTOVI": 2.257630343041064, "BUMETANIDE": 3.851261225899821, "BUSULFAN": 1.4404968188174323, "CABOMETYX": 3.473091488446198, "CAELYX": 14.952238530596354, "CANCIDAS": 1.851063246063832, "CELLCEPT": 2.1146259981820386, "CETUXIMAB": 5.76264336238349, "CICLOSPORIN": 1.0456134266671682, "CIMZIA": 1.1241166653760295, "COAPROVEL": 2.0881863396738662, "COTELLIC": 1.1052598103727804, "CUBICIN": 5.298761139421984, "CYRAMZA": 23.18550861369721, "DARZALEX": 1.2643805783608644, "DOCETAXEL": 4.070969174074145, "DOXORUBICIN": 7.142306990121552, "EFIENT": 1.0170161477057214, "ELIQUIS": 1.0495753086900614, "EMEND": 1.1125085061818167, "ENBREL": 1.4187494715308482, "ERBITUX": 14.457815572296562, "ERIBULIN": 3.844302313135437, "ERLEADA": 11.244950130255395, "ERLOTINIB": 3.105004273415171, "ESBRIET": 1.1537879558470558, "ESOMEPRAZOLE": 1.191789761177006, "EVEROLIMUS": 3.2609879601867244, "EXFORGE": 1.1017276877205393, "FASLODEX": 2.644450604344773, "FEBUXOSTAT": 1.6308953806794373, "FILGRASTIM": 1.0747510811461258, "FULVESTRANT": 1.0326226545701285, "GANCICLOVIR": 1.4531734295442431, "GAVRETO": 4.413154285043648, "GAZYVARO": 1.992983958961555, "GEFITINIB": 15.91222092680261, "GIOTRIF": 9.816971239455752, "GLIVEC": 3.256985486366577, "HALAVEN": 20.86194701529745, "HERCEPTIN": 6.659204131341141, "HYCAMTIN": 5.31336863781602, "IBRANCE": 1.3868601265525362, "IMFINZI": 28.94273436018254, "IMNOVID": 4.273957163611622, "INFLIXIMAB": 2.5614844002876835, "INLYTA": 1.5467229544972103, "INTRONA": 4.567996500738476, "IRESSA": 76.98093674836446, "IRINOTECAN": 2.6600711935397268, "JAKAVI": 1.106129965179169, "JANUVIA": 3.407923210034577, "JEVTANA": 6.140435186089639, "KEYTRUDA": 20.56373056633357, "KISQALI": 1.641973648685077, "KYPROLIS": 2.255682987423362, "LEFLUNOMIDE": 1.3348450651744044, "LENVIMA": 4.972714864401161, "LIBTAYO": 2.6902250626939685, "LIXIANA": 1.3477598073666228, "LONSURF": 1.1077389796069514, "LYNPARZA": 8.120211217308196, "MABTHERA": 6.6573274215883895, "MEKINIST": 1.398449324729439, "METHOTREXATE": 3.1066998989057337, "MICARDIS": 5.720546157244377, "MULTAQ": 2.251515553064867, "MYCOPHENOLATE": 1.3401734744134532, "NEXAVAR": 2.0728150186380643, "NIVOLUMAB": 6.806957161231257, "NOT": 1.004908603232454, "OFEV": 2.848202196193612, "OLAPARIB": 1.5493134068921912, "OPDIVO": 15.237270037331374, "OPSUMIT": 1.1224299052154154, "OSIMERTINIB": 16.746301250464988, "PACLITAXEL": 3.267595172648825, "PANITUMUMAB": 8.23785319977784, "PEGASYS": 3.715013316673896, "PEGINTERFERON": 2.073324629199424, "PEGINTRON": 5.369333950365591, "PEMBROLIZUMAB": 3.30496325809951, "PEMETREXED": 3.037791356837816, "PERJETA": 2.9442108924753807, "PIRFENIDONE": 4.001933157703228, "PLAVIX": 2.006127152272874, "POMALIDOMIDE": 1.7618268129113743, "RADIATION": 2.367174071577374, "RAPAMUNE": 6.669387723052361, "REBETOL": 1.4258615036582418, "REMICADE": 5.1745275017153975, "RILUTEK": 10.14147402809956, "RILUZOLE": 11.600384773928296, "RINVOQ": 1.4105916352076453, "RITUXIMAB": 5.822639004511467, "RIXATHON": 2.103770410507968, "ROACTEMRA": 1.027067741156147, "SIMPONI": 1.7795008273238722, "SKYRIZI": 1.8406466206567604, "SOVALDI": 1.2419486200039938, "SPRYCEL": 1.4278597635402863, "STIVARGA": 1.0608090943798387, "TACROLIMUS": 1.2183853775088986, "TAGRISSO": 47.55755804580372, "TAMIFLU": 1.2067865267676148, "TARCEVA": 9.02994101022334, "TAXOTERE": 8.553226188585219, "TEGAFUR": 5.915587462163558, "TEMODAL": 2.038499602830289, "TEMSIROLIMUS": 5.73365439118869, "TOCILIZUMAB": 1.435788701769536, "TOPOTECAN": 2.446565015257592, "TORISEL": 25.40951788744201, "TRACLEER": 1.052416439338689, "TRASTUZUMAB": 3.606164845095734, "VECTIBIX": 25.11126217969301, "VEKLURY": 1.048454884278608, "VELCADE": 2.76094355520009, "VFEND": 1.517334440034129, "XALKORI": 5.420917694929534, "XARELTO": 1.443066646324176, "XELODA": 2.612142748915216}
\ No newline at end of file
+{"null": 0.9814585982551852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4515.json
index c7c2b56f017..12d3fd45b79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4515.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4515.json
@@ -1 +1 @@
-{"BIKTARVY": 195.03934183053948, "JARDIANCE": 10.219235685578544}
\ No newline at end of file
+{"null": 6.94783504036805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4516.json
index e06cd5cbc30..df1929b4745 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4516.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4516.json
@@ -1 +1 @@
-{"ARAVA": 14.617737341870194}
\ No newline at end of file
+{"APIXABAN": 40.44618222155477, "BUDESONIDE": 44.0306050819768, "COMIRNATY": 0.2666779860563, "null": 0.4162828407653873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4517.json
index dae2a8ad4aa..db4dc013f63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4517.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4517.json
@@ -1 +1 @@
-{"ALENDRONATE": 184.7584371140261, "APIXABAN": 14.593461593957606, "ATRIPLA": 16.00146844249128, "BIKTARVY": 2.508563819178304, "BUPIVACAINE": 6.85830655674908, "BUPRENORPHINE": 2.662849265182701, "BYETTA": 4.3980560705519895, "COSENTYX": 2.287497937807741, "DULOXETINE": 5.0384384093659165, "ELIQUIS": 1.5199950837074157, "ENBREL": 1.746816194286171, "EVISTA": 6.5505886250028365, "HUMALOG": 2.2486722254043072, "IBUPROFEN": 1.927835732227592, "JANUMET": 3.022681062167986, "JANUVIA": 2.559528055596142, "LYRICA": 3.2879976125788755, "METHOTREXATE": 2.230448978354386, "SIMPONI": 1.0944424398825512, "STRIBILD": 6.914664223853307, "SUBOXONE": 2.79680672844321, "TASIGNA": 2.514240863974114, "TRUVADA": 6.447042394555401, "VIAGRA": 2.516620130317171, "VIREAD": 3.236502444989977, "XELJANZ": 2.401744988660555, "XYREM": 5.197283268681771, "ZOSTAVAX": 10.702832518537573}
\ No newline at end of file
+{"null": 0.8135245930740926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4518.json
index 5e84d68bf51..8a75066dc02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4518.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4518.json
@@ -1 +1 @@
-{"ATRIPLA": 1.5867729013611762, "BOSULIF": 16.77667193430694, "ELIQUIS": 1.1183261637453816, "ENBREL": 12.63241443450103, "ESOMEPRAZOLE": 12.922795790440302, "HUMALOG": 1.541196416135186, "HUMIRA": 3.1509625233342105, "IBUPROFEN": 4.621827501322883, "LANTUS": 2.325655146174492, "LYRICA": 4.947066718841611, "SIMPONI": 1.8655211320778256, "STELARA": 1.817931540154116, "SUBOXONE": 3.107095275133679, "SUTENT": 1.233647970413414, "TIVICAY": 25.18928080442944, "TRUVADA": 1.4734838212567614, "VIAGRA": 4.108976633062696, "XELJANZ": 2.681178559619572, "ZOSTAVAX": 8.803671769929613, "null": 1.0579005059867146}
\ No newline at end of file
+{"null": 1.2991879801778887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4519.json
index d8e93e53724..5f32e57cb42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4519.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4519.json
@@ -1 +1 @@
-{"null": 1.075788706140475}
\ No newline at end of file
+{"null": 2.6528177334228498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/452.json
index d2a7ec61474..8220056f47d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/452.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/452.json
@@ -1 +1 @@
-{"ABILIFY": 6.923220431133673, "BRINTELLIX": 50.53299850638077, "CYMBALTA": 4.295001048573446, "PREGABALIN": 11.818784617089475, "VIAGRA": 26.84877206451416, "null": 4.817993371418747}
\ No newline at end of file
+{"COMIRNATY": 1.734742060942553, "CYMBALTA": 1.843935181144544, "GARDASIL": 11.178778725263795, "NIMENRIX": 11.163051616019644, "SPIKEVAX": 2.121293836070407, "TOZINAMERAN": 8.84626198292469, "VAXZEVRIA": 0.797313541695961, "ZOSTAVAX": 13.0498302929037, "null": 0.1685496681179476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4520.json
index 5eb2d3c8903..12c10f1bf39 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4520.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4520.json
@@ -1 +1 @@
-{"SIMPONI": 14.72022707437045, "null": 1.0671152947436566}
\ No newline at end of file
+{"NOVOSEVEN": 5911.667594544416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4521.json
index 081cb12588d..7891d5b06f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4521.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4521.json
@@ -1 +1 @@
-{"APIDRA": 1.433977801841744, "ATRIPLA": 2.168589481816562, "AUBAGIO": 3.798083180373204, "BENLYSTA": 2.167926738944617, "BENRALIZUMAB": 64.67483208994119, "BUPRENORPHINE": 1.3524894960772074, "BUSULFAN": 3.254940609237684, "BYETTA": 1.9483304195747757, "CANNABIDIOL": 18.95311135418196, "COSENTYX": 1.1499967833258775, "CYMBALTA": 1.444726300734582, "ELIQUIS": 1.0585546903028378, "ENBREL": 3.064529740748831, "EXFORGE": 3.2890801210137166, "FAMPYRA": 3.760405865652095, "FASLODEX": 1.860039394522198, "FENTANYL": 1.444722575290774, "FORSTEO": 2.876095986875926, "GARDASIL": 1.1463699748679466, "HUMALOG": 2.97393137794468, "HUMIRA": 6.057971659353998, "IBUPROFEN": 2.270474365814132, "JAKAVI": 1.5113361216413752, "JANUMET": 1.2703173815518516, "LANTUS": 3.4612659910634456, "LEVEMIR": 2.1369276490123568, "LYRICA": 9.016357387725412, "ORENCIA": 16.25229229033568, "OZEMPIC": 16.132358276767903, "REVATIO": 2.721554729845801, "RINVOQ": 2.8548079335450582, "SIMPONI": 4.112048057089912, "STELARA": 1.7947803842611143, "STRIBILD": 1.6730284104570328, "SUBOXONE": 3.641917602034987, "TASIGNA": 2.0117182731620606, "TRUVADA": 1.7221467460758286, "VIAGRA": 5.250956694623164, "XELJANZ": 3.77022404723309, "XOLAIR": 1.0427626536750576, "XYREM": 7.969155623542485, "ZOSTAVAX": 4.432769781081531, "null": 1.012023888381254}
\ No newline at end of file
+{"KEPPRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4522.json
index 76ffdcb98d5..cef4462511f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4522.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4522.json
@@ -1 +1 @@
-{"ARAVA": 20.58020249263744, "ATRIPLA": 2.8791322446840857, "TRUVADA": 5.99790697712559}
\ No newline at end of file
+{"HEMLIBRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4523.json
index a9032dd592f..aae6c76b45f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4523.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4523.json
@@ -1 +1 @@
-{"CICLOSPORIN": 2.978480134782923, "CIMZIA": 2.368664413605335, "CUBICIN": 21.184428349468572, "PEGINTRON": 5.502203486851474, "ROACTEMRA": 23.955481382886827, "STELARA": 4.989373212359169}
\ No newline at end of file
+{"null": 1.0186082156109315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4524.json
index ffc420aca3a..23fd019f5cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4524.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4524.json
@@ -1 +1 @@
-{"HUMIRA": 53.996061640104784, "ROTATEQ": 100.94140798348938}
\ No newline at end of file
+{"ADVATE": 7454.559016309977, "ELOCTA": 1020.4188000615862, "EPTACOG": 284.07402197546674, "HELIXATE": 2562.360690650658, "KOGENATE": 2221.579916647552, "NOVOSEVEN": 30.2553417773186, "OCTOCOG": 1707.5779513017712, "PEGINTERFERON": 4.734202100470303, "null": 0.9039695341564324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4525.json
index 0db0e04d65c..f74386f6b75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4525.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4525.json
@@ -1 +1 @@
-{"null": 20.70010675939629}
\ No newline at end of file
+{"null": 1.3419956826253077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4526.json
index 55c71693466..b0c7925e37f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4526.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4526.json
@@ -1 +1 @@
-{"null": 2.184478674164116}
\ No newline at end of file
+{"PEGASYS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4527.json
index af36630ae72..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4527.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4527.json
@@ -1 +1 @@
-{"BRIVARACETAM": 1301.3554673539454}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4528.json
index f71ae93abc5..f77695ebfa4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4528.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4528.json
@@ -1 +1 @@
-{"COMIRNATY": 5.3119641784435485}
\ No newline at end of file
+{"STELARA": 169.62123683563522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4529.json
index 4025a372d67..69911c20242 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4529.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4529.json
@@ -1 +1 @@
-{"null": 1.5865786303422296}
\ No newline at end of file
+{"ENTYVIO": 86.98014732286052, "STELARA": 98.00656070437594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/453.json
index 22c35d5291a..7f1711da565 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/453.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/453.json
@@ -1 +1 @@
-{"APIXABAN": 19.613382525324305, "AVAMYS": 7.543077166591415, "BENLYSTA": 1.0409252216528633, "CHAMPIX": 1.687337774794429, "COMIRNATY": 2.4111440495695606, "COVID19": 1.246417224561771, "FASENRA": 1.8567084030522727, "FIRDAPSE": 2.156678766324315, "MICARDIS": 1.1369681033603505, "NUCALA": 1.2274273168415737, "RELVAR": 2.0925802073220106, "SPIKEVAX": 1.5441109738890906, "TOZINAMERAN": 2.807698796947334, "VAXZEVRIA": 1.6492778418266527}
\ No newline at end of file
+{"COMIRNATY": 1.4112247038733006, "DULOXETINE": 11.694196249390338, "FENTANYL": 11.034650496853224, "GARDASIL": 8.299626783196151, "QUTENZA": 49.4717389225508, "SHINGRIX": 5.411382948831568, "SPIKEVAX": 0.683098454902343, "TOZINAMERAN": 0.9736288936184284, "VAXZEVRIA": 1.43075728418808, "null": 0.6235620777445823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4530.json
index df5360cd04d..772cae648be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4530.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4530.json
@@ -1 +1 @@
-{"null": 10.368582664778728}
\ No newline at end of file
+{"ADALIMUMAB": 6.360422721300931, "AZATHIOPRINE": 17.76656242236669, "BUDESONIDE": 16.046685109810927, "COMIRNATY": 0.1471924418985623, "COSENTYX": 6.010836396606786, "ENTYVIO": 76.93288311293163, "HUMIRA": 39.44553018694027, "INFLIXIMAB": 44.399033910541874, "RINVOQ": 22.822491508261507, "SIMPONI": 4.649867709614697, "STELARA": 20.97642235710013, "VAXZEVRIA": 0.1204264239571507, "XELJANZ": 26.227119525057848, "null": 0.2110566075894747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4531.json
index 2fc89935ed5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4531.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4531.json
@@ -1 +1 @@
-{"ZYPREXA": 4.208933860377842, "null": 1.6512968717035437}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4532.json
index b6967106e6b..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4532.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4532.json
@@ -1 +1 @@
-{"ENTYVIO": 31.506642033526965, "KEYTRUDA": 8.197828217190049, "SUTENT": 5.006097738890476}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4533.json
index 7a754831490..de0edb9a6d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4533.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4533.json
@@ -1 +1 @@
-{"null": 1.1519462263089952}
\ No newline at end of file
+{"XELODA": 255.86707061670367, "null": 1.8503316605206648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4534.json
index a0248488f4b..b144a0b184e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4534.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4534.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 10.42984206444636, "null": 4.8844696433317205}
\ No newline at end of file
+{"null": 1.3152488223303498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4535.json
index 15c86a4ffcf..04fcd71881c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4535.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4535.json
@@ -1 +1 @@
-{"APIDRA": 3.23129869500408, "BRILIQUE": 20.57750518979222, "BRINTELLIX": 2.372153769988862, "CLOPIDOGREL": 7.588197071354648, "COSENTYX": 1.5215561435909537, "EFIENT": 19.750451417370893, "ELIQUIS": 13.467533117786372, "LIXIANA": 50.37330192525222, "MEPOLIZUMAB": 5.839601293681031, "NEXAVAR": 1.8722276635941943, "NOXAFIL": 13.06149933180976, "PLAVIX": 8.89784697878515, "ROACTEMRA": 2.2840997311813798, "SIMPONI": 1.7053974314228295, "SPRYCEL": 2.6777595367461493, "STIVARGA": 5.545258221650082, "SUTENT": 2.5873097608556184, "VOTRIENT": 1.843249362778289, "XARELTO": 4.10846404499321, "null": 1.0449531849963072}
\ No newline at end of file
+{"null": 2.1241031479313834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4536.json
index 304760a8e41..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4536.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4536.json
@@ -1 +1 @@
-{"null": 1.0791703614449888}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4537.json
index 5ba438fbee4..9d0248a0479 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4537.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4537.json
@@ -1 +1 @@
-{"null": 5.030340738416564}
\ No newline at end of file
+{"null": 1.2697170836939948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4538.json
index 1190f36df32..58b53ffedbc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4538.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4538.json
@@ -1 +1 @@
-{"AVANDIA": 1.2006435029764448, "AVASTIN": 2.9830168985159258, "CELLCEPT": 2.2717768058667147, "CLOPIDOGREL": 2.246694967618632, "ELIQUIS": 1.154837661074665, "KEYTRUDA": 1.1200514040267262, "LEVETIRACETAM": 2.0691279262923548, "NEXAVAR": 1.065603737271715, "NOVOSEVEN": 38.035769153883145, "OLANZAPINE": 1.4219357097510277, "PEGASYS": 1.3337408813804483, "ROACTEMRA": 3.0777713132913496, "SOLIRIS": 1.857797147964562, "SUTENT": 1.0997074314117037, "TRACLEER": 2.097674721476978, "null": 1.4453089927381084}
\ No newline at end of file
+{"ABILIFY": 1.846520273416382, "AIMOVIG": 6.8489040889852495, "CLOPIDOGREL": 2.099633444454991, "COMIRNATY": 0.0741771771636467, "CYMBALTA": 1.8043192673693724, "ELIQUIS": 0.6865113453634104, "FENTANYL": 3.0150532898379967, "FORSTEO": 1.8660191884220017, "JANUMET": 3.573772636553069, "KEPPRA": 1.668651015148842, "KIVEXA": 34.57568742409237, "OLANZAPINE": 6.011740708914863, "SPINRAZA": 6.859016139206288, "SUBOXONE": 1.66816457352619, "TOVIAZ": 6.322670950683489, "VAXZEVRIA": 0.041787058516663, "VELTASSA": 19.02855262070299, "ZYPREXA": 2.451650984361995, "null": 2.814805456896553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4539.json
index d266d8dc562..39a3212223e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4539.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4539.json
@@ -1 +1 @@
-{"null": 1.532334738604865}
\ No newline at end of file
+{"AFINITOR": 2.152223558873582, "APIXABAN": 0.5616172072225304, "ARAVA": 0.1030420531925392, "AUBAGIO": 0.9488003502672178, "AVASTIN": 0.6171183491047333, "AZATHIOPRINE": 0.758729517557258, "BRILIQUE": 3.231692949457732, "BUMETANIDE": 22.72127019674856, "BYDUREON": 0.5007922303483564, "CELLCEPT": 0.8580086428151106, "CHAMPIX": 0.6002870225440664, "CIMZIA": 0.3514693941225681, "CLOPIDOGREL": 14.02075536770884, "COMIRNATY": 0.1486909884675243, "COSENTYX": 0.7080555742606555, "CYMBALTA": 0.2815117483738359, "ELIQUIS": 6.106850083841417, "ENOXAPARIN": 1.7335057834335788, "ENTRESTO": 0.3836155417615663, "ENTYVIO": 0.7591890455467939, "ENZALUTAMIDE": 4.0812958620843895, "ESBRIET": 0.9368548711395088, "EXJADE": 2.8929527530932333, "FENTANYL": 0.5414397787734249, "FORSTEO": 1.1524454342023185, "GLYCOPYRRONIUM": 5.918613933203575, "HARVONI": 1.3654484329738967, "IBRANCE": 0.4073915947067469, "IBUPROFEN": 1.6050902365415671, "JAKAVI": 1.0462935466103251, "JANUMET": 0.8062810803687078, "JANUVIA": 1.190693425568124, "JARDIANCE": 0.5421988783826716, "KALETRA": 1.8214404207849288, "KEPPRA": 0.2672036862859656, "KEYTRUDA": 0.4226583435531237, "LEVOFLOXACIN": 0.7880418913765544, "LIXIANA": 9.728128382810135, "MEKINIST": 0.9388949206055384, "MEPOLIZUMAB": 0.5658373326342271, "MICARDIS": 2.0671097731412917, "MMRVAXPRO": 0.4150456058819112, "NEXAVAR": 3.241241134641345, "OFEV": 2.76097139749974, "OLANZAPINE": 0.264464998160521, "OPDIVO": 0.6026509959570017, "OPSUMIT": 1.7803974667305298, "PASIREOTIDE": 49.47961987141578, "PEGASYS": 1.5681755675038271, "PEGINTRON": 1.0564283422538685, "PLAVIX": 10.373396913124814, "PRADAXA": 3.6572667401456633, "REVATIO": 1.4507041849682374, "RINVOQ": 0.6771736646861175, "ROTATEQ": 23.57647510891971, "SAXENDA": 0.7318368496180768, "SOLIRIS": 0.5545593436017852, "SPIKEVAX": 0.1819638553540974, "SPRYCEL": 1.4155717073295937, "STIVARGA": 2.045355825407793, "SUTENT": 2.147041510627341, "TAMIFLU": 2.5203141312227006, "TICAGRELOR": 16.77884091353526, "TOZINAMERAN": 0.39904062250948, "TRACLEER": 0.9018947588910838, "TWINRIX": 1.3140353321399787, "VAXZEVRIA": 0.1407329919111522, "VOTRIENT": 1.7409794716096454, "XARELTO": 2.1264585238691427, "XELJANZ": 0.6300385628882921, "XOLAIR": 0.3798827133312003, "XTANDI": 0.3568481185887433, "null": 1.9328479199761377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/454.json
index b122cca6ed8..a896cfdbd37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/454.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/454.json
@@ -1 +1 @@
-{"ABILIFY": 811.7473321207051, "ARIPIPRAZOLE": 42.1618890718443, "LURASIDONE": 275.6954898661859, "OLANZAPINE": 11.127151250086804}
\ No newline at end of file
+{"CYTARABINE": 25.408759514637143, "ICLUSIG": 129.94614167075676, "null": 0.4662938824499528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4540.json
index 17ae1ba0048..697c6d836d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4540.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4540.json
@@ -1 +1 @@
-{"null": 2.4268961105938494}
\ No newline at end of file
+{"AIMOVIG": 9.384499500005244, "CLOPIDOGREL": 2.869427641344468, "COMIRNATY": 0.0447674320272231, "ELIQUIS": 0.9692566275494472, "ENTRESTO": 2.565934927019133, "ENTYVIO": 5.763647701938968, "JARDIANCE": 3.631628422864468, "SPIKEVAX": 0.1211933580311613, "SUTENT": 1.5394458882656767, "TEDUGLUTIDE": 249.298143700698, "TRULICITY": 6.124392695066311, "VAXZEVRIA": 0.0837670247588911, "VELTASSA": 26.004480889399872, "XELJANZ": 1.965812050573779, "XTANDI": 2.7048557744654835, "null": 2.037424503433141}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4541.json
index b5a92d9d1b8..fe8e40913ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4541.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4541.json
@@ -1 +1 @@
-{"AFINITOR": 18.58988144173605, "BYETTA": 19.22185324912504, "CABOMETYX": 28.615613417368333, "FASLODEX": 31.554593352549208, "JANUMET": 20.113043053081725, "MEKINIST": 21.687245922570543}
\ No newline at end of file
+{"COMIRNATY": 0.1956085792299736, "PEGASYS": 1.40063931622347, "ROTATEQ": 11.023061783310832, "SUTENT": 0.8661379314298795, "VAXZEVRIA": 0.1446276960451278, "XELJANZ": 2.1372080246099943, "null": 2.5314136450946134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4542.json
index 23b055efad1..645108a76d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4542.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4542.json
@@ -1 +1 @@
-{"null": 3.77657001277882}
\ No newline at end of file
+{"AVASTIN": 4.122861547296017, "BOSULIF": 8.588930549754554, "BUDESONIDE": 1.1075722032511732, "CAPECITABINE": 3.623931464055417, "CELLCEPT": 5.7049375472028, "CLOPIDOGREL": 1.9763490499424223, "COMIRNATY": 0.4258575162875552, "COSENTYX": 0.9375025595733272, "DEXAMETHASONE": 2.2098825166835034, "ELIQUIS": 0.8181791189210303, "ENTYVIO": 11.179882676348289, "HUMIRA": 12.286423724190977, "IBRANCE": 1.4119560328225051, "INFLIXIMAB": 30.192664472519443, "INLYTA": 2.982929618361298, "KEYTRUDA": 1.6833887250537911, "LUTATHERA": 27.946625081114437, "LUTETIUM": 61.352075302252274, "NEXAVAR": 1.5386221160182758, "OFEV": 27.11674947633393, "PEGASYS": 0.7967997163008518, "ROTATEQ": 9.737524210947472, "SPIKEVAX": 0.1205061745570617, "SUTENT": 2.4753697147265905, "TOZINAMERAN": 0.310053025070053, "VAXZEVRIA": 0.1969729489513517, "XELJANZ": 4.560758647460472, "XTANDI": 1.2497071399133342, "null": 1.163752887740297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4543.json
index c4890a366a6..de5c93485e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4543.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4543.json
@@ -1 +1 @@
-{"null": 1.9355590754856575}
\ No newline at end of file
+{"BUPIVACAINE": 510.91182031405225, "null": 0.609726734379986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4544.json
index 59e0b271c41..b617d5946c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4544.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4544.json
@@ -1 +1 @@
-{"ABILIFY": 2.3371158770762417, "AFINITOR": 3.31715443991416, "AIMOVIG": 4.314971690625816, "AMINOSALICYLIC": 1.0975771959739489, "ARAVA": 1.0363272681054965, "ARIPIPRAZOLE": 1.4900803389623796, "ARZERRA": 19.9927447730106, "AVASTIN": 8.377826869129965, "BEDAQUILINE": 1.6187399471008932, "BEVACIZUMAB": 3.333086100123297, "BRAFTOVI": 5.950092364101555, "BUPRENORPHINE": 1.222562546092142, "BYDUREON": 1.2338817370745268, "CABOMETYX": 1.1494030782645914, "CAELYX": 4.048924344642032, "CAPECITABINE": 1.313824791964228, "CELLCEPT": 1.0474456170338915, "CIMZIA": 3.227984517342913, "COTELLIC": 3.0566396679970795, "CYTARABINE": 1.5138618585134092, "DOCETAXEL": 2.5208705875980018, "EMEND": 3.75917015407998, "ENTYVIO": 9.287204766367726, "ERBITUX": 3.825345488288227, "ESBRIET": 1.2402839866825224, "FIRDAPSE": 2.586779812852288, "FORSTEO": 2.6225883692580148, "HIZENTRA": 2.3160482482814104, "HUMIRA": 2.1372937451896123, "IBRANCE": 1.7260783354066436, "INCRUSE": 2.5006485524496425, "INFLIXIMAB": 6.1868306263258, "IRESSA": 2.2174715403769296, "IRINOTECAN": 2.8129105644195618, "JAKAVI": 1.3187381831760343, "JANUMET": 1.4855929213111474, "JANUVIA": 3.330267841869171, "KAFTRIO": 2.6648762699663635, "KALYDECO": 5.374002224770848, "KEYTRUDA": 1.523935112843023, "LONSURF": 9.856655872826012, "LUTATHERA": 11.951299568734497, "LYNPARZA": 4.635870524907283, "MEKINIST": 1.131607922146696, "MVASI": 13.719040317628911, "NEULASTA": 1.051716396757198, "OFEV": 1.7208292706694075, "OLANZAPINE": 2.750556602696021, "OPSUMIT": 1.439469801487386, "ORKAMBI": 12.892589610542563, "PANTOPRAZOLE": 1.068530869325912, "RAPAMUNE": 1.9090060919265504, "REMICADE": 3.2002196832843595, "REVATIO": 1.0530758741393056, "REVESTIVE": 22.70720852555464, "ROTASHIELD": 551.3179136022165, "ROTATEQ": 3.372379828043359, "RUBRACA": 15.398804757094736, "RYBELSUS": 3.5898713116632472, "SAXENDA": 2.91422178720769, "SIFROL": 3.372427046127813, "SKYRIZI": 4.3577606665814885, "SOLIRIS": 1.1374619828625223, "STELARA": 7.975874668911324, "STIVARGA": 3.6023502676312416, "SUTENT": 2.1193668126298646, "TEDUGLUTIDE": 49.144941412122165, "TOVIAZ": 2.8572165296643317, "TRACLEER": 1.0633590527801275, "TREMFYA": 1.4904225754695546, "TRULICITY": 3.9566961672398295, "VEDOLIZUMAB": 13.852601989038355, "VELTASSA": 2.419053203659203, "VFEND": 1.0433181988361206, "VICTOZA": 3.960610521782335, "VIMPAT": 1.5767518034750687, "VOTRIENT": 1.7737787382242445, "XALKORI": 1.5600961924148244, "XELJANZ": 1.4620222870642836, "XELODA": 2.724589771920116, "XTANDI": 1.9625485294146805, "YERVOY": 1.9562256609931976, "ZYPREXA": 1.7037669501882116, "null": 1.4356552974283283}
\ No newline at end of file
+{"PLEGRIDY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4545.json
index 9a33ec9d3d7..a223be252e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4545.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4545.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 25.37263652666409, "SIMPONI": 22.16145748536113, "STELARA": 33.542110172196026, "null": 1.1932904021710675}
\ No newline at end of file
+{"null": 2.3776312885996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4546.json
index 768ba726e06..f700dcf40ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4546.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4546.json
@@ -1 +1 @@
-{"AFINITOR": 1.3349964275220891, "ALIMTA": 4.906375220694746, "AVASTIN": 21.112829183175705, "BEVACIZUMAB": 11.948464949107269, "BRAFTOVI": 4.20298303462268, "CABOMETYX": 5.225968163636565, "CELLCEPT": 3.032883335114489, "CICLOSPORIN": 1.415934196272319, "CIMZIA": 1.529345000681109, "CYTARABINE": 3.5843806823334226, "DEXAMETHASONE": 3.0023856313370945, "ENTYVIO": 2.1917088487797582, "FORSTEO": 1.3478045266379843, "FOTIVDA": 25.87302839628541, "HUMIRA": 3.56124689584405, "INLYTA": 5.772307478231756, "IPILIMUMAB": 8.507515880975806, "JEVTANA": 7.166339622856966, "KEYTRUDA": 5.594446422647323, "LENVIMA": 11.51869585128959, "LEVETIRACETAM": 3.904256428394869, "MEKINIST": 3.960601882081469, "METHOTREXATE": 1.0563743729508457, "NEXAVAR": 2.091346001228908, "OFEV": 4.069453398153047, "OPDIVO": 3.459910889222848, "PAZOPANIB": 8.819903321288153, "PEMBROLIZUMAB": 2.306969561045507, "RINVOQ": 6.048539483244509, "RITUXIMAB": 4.144391115874987, "ROACTEMRA": 13.508199682716992, "ROTATEQ": 2.3091471269116965, "SOLIRIS": 3.808176551217093, "STELARA": 3.221121869111768, "STIVARGA": 5.331124309140023, "SUTENT": 4.532469958492267, "TOCILIZUMAB": 23.396485670310167, "TORISEL": 9.980368857218483, "VOTRIENT": 9.403325405167545, "XELJANZ": 2.9457518964826828, "YERVOY": 62.87074018415184}
\ No newline at end of file
+{"REMICADE": 220.88952195431392, "null": 1.357490168032103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4547.json
index 296d0b236a7..b38e554f8ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4547.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4547.json
@@ -1 +1 @@
-{"ARAVA": 3.0837720061716, "ELIQUIS": 3.3087692493811622, "FORSTEO": 5.780735429657907, "null": 1.5910025834326886}
\ No newline at end of file
+{"GARDASIL": 88.78244063081932, "null": 1.1414720922686423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4548.json
index d52527768d6..215f8d6840d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4548.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4548.json
@@ -1 +1 @@
-{"OLANZAPINE": 11.010588333359712, "null": 2.7898954726195164}
\ No newline at end of file
+{"ELIQUIS": 159.71174600426363, "JARDIANCE": 28.13868120366488, "null": 0.3263997766413352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4549.json
index 3d1fc6e05b4..679798655e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4549.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4549.json
@@ -1 +1 @@
-{"CICLOSPORIN": 4.096622405457169, "CIMZIA": 15.434734262646735, "ENTYVIO": 33.802855059443964, "HUMIRA": 18.2590565790706, "JANUMET": 7.432977143356597, "LANTUS": 1.905894799143072, "ROTATEQ": 28.288548034055815, "SIMPONI": 3.927637104681093, "STELARA": 36.60298156918995, "XELJANZ": 3.5075153490474387}
\ No newline at end of file
+{"BYETTA": 4.205563974512833, "CICLOSPORIN": 1.121439170147137, "CRIZOTINIB": 120.43850822071887, "CYMBALTA": 0.7154347422966321, "DEXAMETHASONE": 2.9292348358544604, "EPIVIR": 14.384959634017967, "EXJADE": 2.341738829912798, "FIRDAPSE": 11.745868033030764, "JANUMET": 6.881409334048459, "JANUVIA": 3.8423422431972822, "KEPPRA": 1.0910627497690253, "KEYTRUDA": 1.1393462309738993, "LAMIVUDINE": 11.808773758426742, "NPLATE": 8.235299558146043, "ORKAMBI": 14.970730733254054, "PEGASYS": 4.895895703818265, "ROTATEQ": 12.46705238011334, "SUBOXONE": 5.414195948183034, "SUTENT": 1.4067805365932542, "SYNAGIS": 22.67603657821293, "TRACLEER": 3.595594437885426, "XTANDI": 4.361504152245531, "null": 1.3843061126857137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/455.json
index 90e84bb5c69..0dbd211d742 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/455.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/455.json
@@ -1 +1 @@
-{"COMIRNATY": 9.018223918948843, "CYMBALTA": 4.885955968575725, "SPIKEVAX": 1.490572751432701, "TOZINAMERAN": 2.924659081092174}
\ No newline at end of file
+{"ABACAVIR": 0.2224790383432172, "ABATACEPT": 6.171295376896089, "ABILIFY": 0.2913808882585231, "ABRAXANE": 0.4391302983662246, "ACETAMINOPHEN": 7.8681949820267825, "ADALIMUMAB": 9.903465517031082, "ADENURIC": 0.784632909295539, "AERIUS": 0.4056961156631675, "AFINITOR": 0.4401078518179019, "AIMOVIG": 5.462129346050119, "ALDARA": 0.4742036410325603, "ALEMTUZUMAB": 0.2781333012285507, "ALIMTA": 0.3081235107588461, "ALL": 1.0618875894851585, "ALOXI": 3.578587789463588, "ALPELISIB": 1.0880045769699564, "AMINOSALICYLIC": 1.2519722204874846, "ANAKINRA": 0.3571841504210908, "APIDRA": 0.0925069131542516, "APIXABAN": 2.3391038466101493, "APREMILAST": 4.916715467900437, "APREPITANT": 11.53889758522827, "APROVEL": 0.3058946375865365, "ARANESP": 0.1852568296644775, "ARAVA": 12.548428878675352, "ARIPIPRAZOLE": 0.9942886004925608, "ARIXTRA": 1.0843285695754168, "ASPARAGINASE": 0.1454529650439815, "ATEZOLIZUMAB": 1.2036472103661873, "ATRIPLA": 0.0074964721115476, "AUBAGIO": 11.52851498970459, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4550.json
index 0f3adc41d2a..e8255c86321 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4550.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4550.json
@@ -1 +1 @@
-{"ANAKINRA": 1036.883909789384, "ENBREL": 26.343019894896837}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4551.json
index b3b0d795ee4..0e1099b0de0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4551.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4551.json
@@ -1 +1 @@
-{"CIMZIA": 19.61296177341615, "ENTYVIO": 59.98262235847874, "FENTANYL": 5.955685836066354, "HUMIRA": 10.185518702842876, "STELARA": 91.77072364467506}
\ No newline at end of file
+{"null": 0.4795028478921596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4552.json
index 1974115bc04..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4552.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4552.json
@@ -1 +1 @@
-{"MEPOLIZUMAB": 581.5570786562088}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4553.json
index b2773e63a46..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4553.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4553.json
@@ -1 +1 @@
-{"null": 2.141940521401468}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4554.json
index e0942f72557..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4554.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4554.json
@@ -1 +1 @@
-{"null": 1.1422885138152594}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4555.json
index 4c291829ffd..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4555.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4555.json
@@ -1 +1 @@
-{"ARAVA": 1.0536998375357498, "CIMZIA": 3.956202933851017, "ENTYVIO": 16.303260633182845, "HUMIRA": 23.68398022720706, "STELARA": 4.220595513349275, "SUTENT": 1.988857117652974, "null": 1.5133868159898043}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4556.json
index a15c649eaec..f115e465f11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4556.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4556.json
@@ -1 +1 @@
-{"CELLCEPT": 21.864150991807485, "null": 7.674203765957176}
\ No newline at end of file
+{"null": 8.985620441455536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4557.json
index 93c1c880cf7..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4557.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4557.json
@@ -1 +1 @@
-{"CABOMETYX": 12.841478638522553, "CIMZIA": 2.8247976204507483, "ENBREL": 4.916635187926729, "JANUMET": 8.98328689544327, "KEYTRUDA": 3.8889013239885006, "LONSURF": 22.33568371094168, "OPSUMIT": 9.08150962349295, "SUTENT": 1.9443013871455264}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4558.json
index 559e9b8e231..d6922f5e0b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4558.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4558.json
@@ -1 +1 @@
-{"ABACAVIR": 4.193291201577518, "BUDESONIDE": 1.65776598138095, "CLOPIDOGREL": 4.639135301849243, "ELIQUIS": 3.622259578048948, "ENOXAPARIN": 46.468432174139, "INHIXA": 194.17758788228116, "PLAVIX": 9.32629301844029, "XARELTO": 7.838536786592517, "null": 3.878139371022612}
\ No newline at end of file
+{"null": 4.685085774816137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4559.json
index e497d2927d4..b84b309d431 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4559.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4559.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.423184471341977, "CLOPIDOGREL": 6.322121133285243, "CYTARABINE": 3.026902710183785, "ELIQUIS": 9.44721658955165, "ENOXAPARIN": 32.631437582704656, "NEXAVAR": 3.892114291958697, "NOVOSEVEN": 26.907526308012773, "PLAVIX": 8.211581888668155, "SUTENT": 1.760456113796434, "VOTRIENT": 3.355343304442659, "null": 2.249400365974449}
\ No newline at end of file
+{"null": 1.9858404412401207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/456.json
index 33271b94927..893f20a356d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/456.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/456.json
@@ -1 +1 @@
-{"null": 1.737401551228939}
\ No newline at end of file
+{"AUBAGIO": 3.5587066548938435, "CHAMPIX": 1.368102862558494, "CIMZIA": 0.9578211802217214, "COMIRNATY": 2.2223593224735665, "DEXAMETHASONE": 1.8159437569637344, "DOCETAXEL": 11.620491977987236, "GARDASIL": 2.779844396609774, "HERCEPTIN": 5.853647743634364, "LEMTRADA": 10.659458968636216, "OLOPATADINE": 508.9692650940183, "PEGASYS": 0.6758229373569884, "RINVOQ": 3.2816221960115097, "SIMPONI": 2.346365668064892, "SPIKEVAX": 1.543199786510672, "STELARA": 3.8707866072502255, "TOZINAMERAN": 1.5839142055402988, "VAXZEVRIA": 0.4666213078869725, "XOLAIR": 1.8434775103370469, "null": 0.5371813843560918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4560.json
index 8e431795c96..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4560.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4560.json
@@ -1 +1 @@
-{"LEVETIRACETAM": 228.95562461413263}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4561.json
index e2998e36555..1b1e859f6e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4561.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4561.json
@@ -1 +1 @@
-{"null": 1.609848241428752}
\ No newline at end of file
+{"FASENRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4562.json
index 886199c8d75..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4562.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4562.json
@@ -1 +1 @@
-{"null": 1.9021034470265756}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4563.json
index 2a432398e6a..3961908b01d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4563.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4563.json
@@ -1 +1 @@
-{"BEOVU": 392.3353624342832, "EYLEA": 1404.1588835979603}
\ No newline at end of file
+{"ILARIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4564.json
index 9defde1104b..e607676af8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4564.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4564.json
@@ -1 +1 @@
-{"AIMOVIG": 1.998435195482384, "ELIQUIS": 4.286797686934121, "EVENITY": 11.291548026712093, "HUMALOG": 2.02433350206806, "IBRANCE": 1.3119048170176215, "LANTUS": 1.390609714065236, "PEGASYS": 1.7033087439091097, "PEGINTRON": 4.749091614008878, "PLAVIX": 4.169441733018772, "SIMPONI": 1.6985234074154625, "STELARA": 2.792653939806947, "XELJANZ": 2.280947130126161, "null": 1.1545011278349695}
\ No newline at end of file
+{"null": 0.5914967197394623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4565.json
index 9a87b409202..cf89bd7c884 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4565.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4565.json
@@ -1 +1 @@
-{"BRILIQUE": 26.691842252699665, "CLOPIDOGREL": 19.586023268805896, "ELIQUIS": 14.808275286788692, "PLAVIX": 19.375652686918187, "null": 1.600745343050176}
\ No newline at end of file
+{"null": 1.9086754803792847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4566.json
index 5040d5bcefe..30380b6ee3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4566.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4566.json
@@ -1 +1 @@
-{"CICLOSPORIN": 5.063869869074814}
\ No newline at end of file
+{"null": 1.719128601799418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4567.json
index 73ab5e3857d..6dd174530c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4567.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4567.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 8.298674014085774, "ASPARAGINASE": 6.028169170140573, "BEDAQUILINE": 4.175270840027901, "CELLCEPT": 1.4377918624963135, "CICLOSPORIN": 4.675219172623604, "COTELLIC": 9.021462063065089, "EFAVIRENZ": 13.749198828075608, "GARDASIL": 1.0031017829431508, "KAFTRIO": 17.41441473106559, "KEPPRA": 2.690756153867914, "KYMRIAH": 3.5156190512935344, "LAMIVUDINE": 8.50540643702899, "MIDAZOLAM": 4.731303430529409, "NAGLAZYME": 21.1625453452651, "NUTROPIN": 66.21940442186816, "OMNITROPE": 36.37607540367611, "SAXENDA": 2.4364285471812592, "SOLIRIS": 1.8489261602447613, "SOMATROPIN": 58.61924593764471, "SPINRAZA": 24.771798699238182, "TEMODAL": 8.991560477816442, "XOLAIR": 1.645663326622907, "null": 1.7179496968848575}
\ No newline at end of file
+{"BIKTARVY": 326.2548304959832, "null": 1.2093357789939485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4568.json
index 5329a3d386e..59f7a66afc7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4568.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4568.json
@@ -1 +1 @@
-{"TEMODAL": 190.82067344463024}
\ No newline at end of file
+{"ABACAVIR": 4.361520189598277, "ATAZANAVIR": 11.121018052112126, "ATRIPLA": 2.36853567198644, "EFAVIRENZ": 15.530059444042344, "EMTRICITABINE": 23.25402452609354, "EXJADE": 8.346222843626329, "HEPSERA": 307.7260100795215, "KALETRA": 56.59641837907686, "LOPINAVIR": 58.44085990009605, "NORVIR": 65.88646132650825, "REYATAZ": 34.118770278916884, "STRIBILD": 6.001312126304554, "TENOFOVIR": 270.4801030760049, "TRUVADA": 15.50414219497317, "VIREAD": 114.53323562815063, "null": 0.634716174449361}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4569.json
index 27248a97017..d2500a8e66a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4569.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4569.json
@@ -1 +1 @@
-{"BYETTA": 64.79127645870685}
\ No newline at end of file
+{"ABACAVIR": 1.0520586596013328, "ADEFOVIR": 68.25145392066845, "ATAZANAVIR": 7.450321314227036, "ATRIPLA": 19.700772038592092, "EMTRICITABINE": 22.815972031634843, "EMTRIVA": 41.46213260682574, "ENTECAVIR": 18.472107891819284, "EXJADE": 10.560227777051518, "GENVOYA": 17.858175899779543, "HARVONI": 3.110091470457843, "HEPSERA": 486.0392539776995, "KALETRA": 11.446248608364026, "LOPINAVIR": 39.72143185987597, "NORVIR": 13.237790094603763, "REYATAZ": 19.91945074203826, "STRIBILD": 17.07001337853639, "TENOFOVIR": 274.5703555001742, "TRUVADA": 35.27945908165026, "VIREAD": 159.86361809160002, "null": 0.0681579028314263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/457.json
index dfa7393146d..457fb3e0b46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/457.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/457.json
@@ -1 +1 @@
-{"ACLIDINIUM": 70.54966664321147, "ARANESP": 4857.661048703754}
\ No newline at end of file
+{"null": 1.1310470291213084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4570.json
index fad188134c4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4570.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4570.json
@@ -1 +1 @@
-{"EVISTA": 96.14445866869367, "SIMPONI": 4.660898297822259, "STELARA": 7.059027030616733, "XOLAIR": 5.399930913896246, "null": 1.936010785324324}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4571.json
index 6093573c5bf..cc5bb4617b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4571.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4571.json
@@ -1 +1 @@
-{"null": 1.8541159603239652}
\ No newline at end of file
+{"COMIRNATY": 0.652934691181988, "JAKAVI": 43.12172376829006, "SPIKEVAX": 0.3580834077624465, "null": 0.8111494388876845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4572.json
index af0143e47a2..c1bbb4b698c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4572.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4572.json
@@ -1 +1 @@
-{"EYLEA": 302.121786975536}
\ No newline at end of file
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4573.json
index c3a53bb46af..fb5a17f0407 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4573.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4573.json
@@ -1 +1 @@
-{"APIDRA": 1.5365783498557322, "AVAMYS": 6.406823546302142, "AZATHIOPRINE": 7.893003272315204, "AZOPT": 58.93334586442949, "BEOVU": 56.8493830803552, "BIMATOPROST": 333.7598422419329, "BRIMONIDINE": 183.10262380635325, "BRINTELLIX": 2.179795843710559, "BRINZOLAMIDE": 184.02015038649944, "BROLUCIZUMAB": 62.04947902726558, "BUDESONIDE": 1.1916490380011446, "CYMBALTA": 1.4187904015599802, "ENBREL": 1.3912768242122315, "EYLEA": 193.96833077091864, "LATANOPROST": 308.75645539874336, "LUMIGAN": 159.09026808163892, "LUXTURNA": 429.7422670112431, "MANNITOL": 23.955267672282307, "MEKINIST": 1.2242733852446634, "MYCOPHENOLATE": 6.39314413551151, "NAGLAZYME": 3.856241412791796, "NEVANAC": 78.22279537298262, "RELVAR": 3.99466733483196, "TOVIAZ": 4.718217787779083, "TRELEGY": 3.964608765707332, "VIAGRA": 3.578398270193223, "null": 1.953756898005115}
\ No newline at end of file
+{"null": 1.1637784968729086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4574.json
index ad9ccb386d7..289b1ceca00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4574.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4574.json
@@ -1 +1 @@
-{"ANIDULAFUNGIN": 1512.9765152147052}
\ No newline at end of file
+{"null": 1.068453339061557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4575.json
index 5a6024be206..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4575.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4575.json
@@ -1 +1 @@
-{"ANIDULAFUNGIN": 697.7867588970669}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4576.json
index 90d62e53fb7..c7efddc0806 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4576.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4576.json
@@ -1 +1 @@
-{"NOVOSEVEN": 1585.301723097751}
\ No newline at end of file
+{"null": 3.697944576707549}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4577.json
index c71973c246a..fa63acb3950 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4577.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4577.json
@@ -1 +1 @@
-{"AVONEX": 2860.8734320198582}
\ No newline at end of file
+{"null": 1.3183814393892817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4578.json
index ae93c906c95..ccdcb0eb1ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4578.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4578.json
@@ -1 +1 @@
-{"COMIRNATY": 7.907296974613479}
\ No newline at end of file
+{"ENBREL": 21.98083171647188, "VAXZEVRIA": 0.4168721622458782, "null": 1.0107092041180954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4579.json
index 8245c0dbf6e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4579.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4579.json
@@ -1 +1 @@
-{"CICLOSPORIN": 6.554110667916862, "PRIVIGEN": 39.990700029654185, "SOLIRIS": 97.73568906188568, "null": 1.3727972421873789}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/458.json
index 3f316808299..a459ef8dbef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/458.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/458.json
@@ -1 +1 @@
-{"null": 10.123542394551846}
\ No newline at end of file
+{"GENVOYA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4580.json
index fac402456a8..5a10c8593c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4580.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4580.json
@@ -1 +1 @@
-{"BRILIQUE": 11.893068078082251, "CLOPIDOGREL": 14.51566134545476, "ELIQUIS": 18.22659708926494, "LIXIANA": 13.1756080849217, "PLAVIX": 12.696408752265803, "null": 1.3761705346672162}
\ No newline at end of file
+{"ABACAVIR": 54.17487555254509, "ATRIPLA": 4.269324761278628, "COMBIVIR": 72.58966387499866, "CRIXIVAN": 439.2645132084237, "KALETRA": 46.16791685529153, "null": 0.3108992661449702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4581.json
index 1687f071d6a..e7275ef5e95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4581.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4581.json
@@ -1 +1 @@
-{"null": 4.637751870891568}
\ No newline at end of file
+{"null": 0.4808447707485204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4582.json
index dfb40441680..ebfd3e5a7d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4582.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4582.json
@@ -1 +1 @@
-{"ABILIFY": 14.927222602381876, "DULOXETINE": 47.56381421089704, "TOZINAMERAN": 1.3418372888064682, "null": 2.35103832431833}
\ No newline at end of file
+{"ABACAVIR": 12.454398859117411, "ATRIPLA": 1.8114802613758492, "BIKTARVY": 18.385815114805084, "COMBIVIR": 19.774919774494677, "COMIRNATY": 0.136759102234842, "DESCOVY": 80.4350097828438, "HUMALOG": 4.636440092893343, "LANTUS": 4.102007307930167, "PEGASYS": 2.1568549551210863, "null": 0.8452384467435372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4583.json
index bdb8316c497..16421ded631 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4583.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4583.json
@@ -1 +1 @@
-{"INFANRIX": 55.15840141036647, "PREVENAR": 219.9261752253154, "ROTARIX": 110.65632499809968, "ROTASHIELD": 607.3828774637363, "ROTATEQ": 2624.760502157841}
\ No newline at end of file
+{"CINRYZE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4584.json
index ef48c1e0e08..7084126e573 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4584.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4584.json
@@ -1 +1 @@
-{"AFINITOR": 3.507314396638059, "AVASTIN": 2.5057372965375158, "BEVACIZUMAB": 5.514887515241198, "CAPECITABINE": 12.296788550554282, "DOCETAXEL": 6.918153166044202, "EVISTA": 38.00910493468018, "FAMPYRA": 7.691554059921631, "FASLODEX": 3.5081668506748995, "FULVESTRANT": 14.67636563893952, "KEPPRA": 1.1862438716026975, "OLANZAPINE": 1.2087964669047508, "PACLITAXEL": 9.354798349180683, "ROACTEMRA": 3.566458064282616, "SIMPONI": 2.896643699582359, "STELARA": 3.4566542650126584, "TESTOSTERONE": 17.47619105370686, "XOLAIR": 2.794409469416894, "null": 4.165501834746796}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4585.json
index 101b0b49e2e..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4585.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4585.json
@@ -1 +1 @@
-{"null": 3.2138035809535523}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4586.json
index 2eaa598f27b..4061401dd7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4586.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4586.json
@@ -1 +1 @@
-{"null": 1.53567740245871}
\ No newline at end of file
+{"null": 1.9146015139537076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4587.json
index fab9294f2cd..daa2ae92c5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4587.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4587.json
@@ -1 +1 @@
-{"FORSTEO": 62.73565020039175}
\ No newline at end of file
+{"ABILIFY": 2.455779454870995, "AERIUS": 2.539826914797604, "AIMOVIG": 0.896229342015781, "ANTIBIOTICS": 8.642087545705975, "APIDRA": 0.6938512202570497, "ARANESP": 0.5203241122757978, "ARAVA": 0.2187314485108428, "ARIPIPRAZOLE": 1.2499212189840865, "ATRIPLA": 1.1393651830578806, "BENLYSTA": 1.8277739334805785, "BRINTELLIX": 2.8320980855035085, "BRIVIACT": 4.423033777376481, "BUPRENORPHINE": 0.7594132582808637, "CHAMPIX": 6.443653022191827, "COMIRNATY": 0.2799176137774434, "COSENTYX": 0.8574128538119115, "CYMBALTA": 2.4943733240005512, "DABRAFENIB": 4.666537695235013, "DULOXETINE": 7.861360926423039, "ELIQUIS": 0.1438847858284019, "ENTRESTO": 0.726034015491847, "EVISTA": 2.632656295440559, "EXFORGE": 1.3288655683308217, "FASENRA": 1.0454543014902582, "FENTANYL": 0.4794161307121557, "FIRDAPSE": 2.305000881015459, "FORSTEO": 0.8253604058127443, "GALVUS": 2.9662039537034484, "GARDASIL": 0.5358762324695432, "HUMALOG": 0.7253904337998498, "IBRANCE": 0.7943033211950752, "IBUPROFEN": 1.2514543404159817, "JAKAVI": 0.8279987929659279, "JANUMET": 1.270997978223174, "JANUVIA": 0.5735835780167435, "KEPPRA": 1.5624990437220263, "KEYTRUDA": 0.2803303999776308, "LANTUS": 1.1351289110846514, "LATUDA": 7.643842398239859, "LEVETIRACETAM": 1.3991367116386844, "LEVOFLOXACIN": 0.6627375789710984, "LYRICA": 2.7157770370146155, "NUCALA": 1.1078363762550727, "OLANZAPINE": 1.846415893820048, "OMALIZUMAB": 1.4227605116349105, "PEGASYS": 0.5696690402935105, "PEGINTRON": 0.3765544431066968, "RELVAR": 2.53138939542242, "SHINGRIX": 0.5924032308493589, "SIFROL": 3.7696767035812018, "SPIKEVAX": 0.342089310977159, "STRIBILD": 1.0693898438405316, "SUBOXONE": 1.9402508641305665, "SUTENT": 0.4958298977152897, "TAMIFLU": 4.375754331430009, "TOZINAMERAN": 0.9688644035246554, "TRULICITY": 0.7323619540086259, "TRUVADA": 1.20188802518762, "TWINRIX": 1.6742308985379704, "VAXZEVRIA": 0.2601830197609069, "VIAGRA": 0.8317486133221177, "VIMPAT": 1.9720956653334083, "XELJANZ": 0.4822755764131122, "XOLAIR": 1.725805519110514, "ZOSTAVAX": 0.594735914584706, "ZYPREXA": 2.039911755356885, "null": 2.383891385641957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4588.json
index 32e340159d7..a96a50dd56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4588.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4588.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.370065114815082, "ARAVA": 5.911467402154835, "COSENTYX": 8.276375766553237, "CYMBALTA": 6.315578445298536, "HUMIRA": 13.012915817241517, "IBRANCE": 5.783308024553341, "OFEV": 18.684351061546703}
\ No newline at end of file
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4589.json
index 329aeccd8ec..ff415505ac1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4589.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4589.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.762866126024607, "COSENTYX": 27.8583954251844, "LEVETIRACETAM": 22.82760212343091}
\ No newline at end of file
+{"CHAMPIX": 2.224498456685196, "COMIRNATY": 0.9006245414734599, "LANTUS": 1.1477153403166145, "SPIKEVAX": 0.3163454793022707, "TOZINAMERAN": 0.6999326703048966, "VAXZEVRIA": 0.4676392840462353, "null": 2.164276648429872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/459.json
index 663bae8d093..1ef3a88f9cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/459.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/459.json
@@ -1 +1 @@
-{"BEOVU": 1357.3753331681553, "BROLUCIZUMAB": 379.5394755689658, "EYLEA": 220.42130832410268, "LEVOFLOXACIN": 4.331710579190829, "null": 1.4033500840725757}
\ No newline at end of file
+{"COMIRNATY": 0.7866103591001672, "DOCETAXEL": 16.11649467259715, "PEGASYS": 3.1805242980303534, "PEGINTERFERON": 24.299120254590505, "null": 0.7063032596076896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4590.json
index 98dd4b95e56..f3216e1f519 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4590.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4590.json
@@ -1 +1 @@
-{"null": 3.457645315486185}
\ No newline at end of file
+{"COMIRNATY": 0.2881454788814722, "VAXZEVRIA": 0.2198979079276551, "null": 3.550593443136789}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4591.json
index e4b2652f84c..6c7f15fc458 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4591.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4591.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"null": 1.0464775269638364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4592.json
index f2732fd19e5..f5ba6bbd9ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4592.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4592.json
@@ -1 +1 @@
-{"BEOVU": 719.8298957214732, "BRAFTOVI": 10.024771499229317, "BROLUCIZUMAB": 521.3094560837853, "COSENTYX": 3.038457437875414, "COTELLIC": 12.17139752720167, "DACLATASVIR": 28.21281420339721, "EYLEA": 79.61471160622825, "IPILIMUMAB": 29.247058088192155, "KEYTRUDA": 1.593365160385788, "MEKINIST": 3.4687485683041044, "POSACONAZOLE": 28.55487422693647, "SIMPONI": 4.692585693953031, "ZELBORAF": 18.59357782861868, "ZOSTAVAX": 2.570573485855684}
\ No newline at end of file
+{"null": 1.387239421952138}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4593.json
index abd9c33c0b4..5f9dc2c7bd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4593.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4593.json
@@ -1 +1 @@
-{"null": 2.158702033383775}
\ No newline at end of file
+{"ABATACEPT": 12.048885045617668, "ADALIMUMAB": 8.084947605440783, "AIMOVIG": 6.181297852908173, "ARAVA": 1.816161213771776, "CICLOSPORIN": 6.767479662260775, "CIMZIA": 4.088949618311697, "COMIRNATY": 0.122199729668177, "COSENTYX": 6.981873402399948, "CYMBALTA": 3.2750711160561, "ENBREL": 11.71110555400744, "GARDASIL": 2.758993614797749, "LANTUS": 1.3884885404796323, "NUCALA": 16.93688311650925, "OMALIZUMAB": 6.0583624283716295, "SPIKEVAX": 0.3102952757422775, "VAXZEVRIA": 0.1066671941905786, "null": 0.4003231792253903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4594.json
index 6d147f9160b..1fa62ca5f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4594.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4594.json
@@ -1 +1 @@
-{"null": 1.162126002253283}
\ No newline at end of file
+{"EVENITY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4595.json
index 708936eb483..09625d32d70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4595.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4595.json
@@ -1 +1 @@
-{"MELPHALAN": 421.6769635803152, "NEVANAC": 1279.1583091864472, "null": 2.163947849098682}
\ No newline at end of file
+{"null": 1.5345798162876387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4596.json
index 6ce64265cbf..c4ed7026bfd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4596.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4596.json
@@ -1 +1 @@
-{"null": 1.7937720800506547}
\ No newline at end of file
+{"ATRIPLA": 29.395048642908076, "STRIBILD": 44.68238171689551, "TRUVADA": 18.65184844518581}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4597.json
index c9359fb4ebf..0cc98ade850 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4597.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4597.json
@@ -1 +1 @@
-{"null": 2.490319740474784}
\ No newline at end of file
+{"ALIMTA": 45.737569991035, "BINOCRIT": 95.85085367940256, "BUSILVEX": 74.02413595356012, "CYTARABINE": 16.05022267978736, "DEXAMETHASONE": 7.264320089277079, "DOXORUBICIN": 14.738893388231258, "EMEND": 80.07372076413918, "JEVTANA": 16.468389662816666, "KEYTRUDA": 4.057648691568108, "MABTHERA": 57.595154942346966, "METHOTREXATE": 8.053817650269835, "NEULASTA": 12.034519595265424, "PEMETREXED": 26.772052895399803, "TAXOTERE": 47.19696517020128, "TEMODAL": 61.711446118932976, "TRODELVY": 51.048881791699, "VFEND": 7.414685828411019, "null": 0.9112181332669472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4598.json
index 7f43d4e6af1..38c3c6d44c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4598.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4598.json
@@ -1 +1 @@
-{"null": 13.164543590896496}
\ No newline at end of file
+{"BEXSERO": 69.45858474914962, "COMIRNATY": 0.2014132588866832, "HEXYON": 53.74010426105814, "INFANRIX": 80.98142815718089, "KEPPRA": 0.6047894261148699, "LEVETIRACETAM": 0.5368135225006829, "MENQUADFI": 44.177967816225895, "MENVEO": 4.88500163110623, "MMRVAXPRO": 61.802680291190384, "NIMENRIX": 45.83363642889816, "NOT": 4.225170179279928, "POLIOMYELITIS": 218.4369009541496, "PREVENAR": 58.558532363690425, "PROQUAD": 81.90154944381175, "ROTARIX": 94.87516685825372, "ROTATEQ": 4.8624118832226975, "SPIKEVAX": 0.211207701271167, "SYNAGIS": 4.45483798342582, "SYNFLORIX": 104.20822628646177, "TAMIFLU": 1.515636576059747, "TOZINAMERAN": 0.3616832966939311, "TWINRIX": 1.854261983841592, "VARICELLA": 276.4066738147391, "VAXZEVRIA": 0.5492879712369594, "null": 3.355915783808505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4599.json
index 817936b56c9..d2516746715 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4599.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4599.json
@@ -1 +1 @@
-{"null": 32.63103118347658}
\ No newline at end of file
+{"COMIRNATY": 0.252808721947654, "JARDIANCE": 8.270063705979563, "NAGLAZYME": 134.86324540865525, "NEULASTA": 18.51688409736594, "null": 0.6109777414426916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/46.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/46.json
index 1eb104f0ce1..e6e67aee351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/46.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/46.json
@@ -1 +1 @@
-{"MISOPROSTOL": 376.5301586356688, "null": 65.16459095163641}
\ No newline at end of file
+{"null": 1.5228310199198265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/460.json
index ae715535582..c439dfc2ef6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/460.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/460.json
@@ -1 +1 @@
-{"EYLEA": 257.3020836062199, "null": 1.932247952740592}
\ No newline at end of file
+{"COMIRNATY": 1.2546580052045029, "PEGINTERFERON": 86.02430164649437, "PEGINTRON": 9.122425473278778, "SPIKEVAX": 0.433804951977977, "null": 0.5378166556132333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4600.json
index fac2b4dcb1e..82b64c15db9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4600.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4600.json
@@ -1 +1 @@
-{"BEOVU": 289.3688999601866, "CIMZIA": 1.7984676058912457, "COSENTYX": 10.13588049167989, "ENBREL": 2.1017291151665374, "EYLEA": 110.45533537298576, "KEYTRUDA": 1.6568722850267243, "ROACTEMRA": 3.913541186695612, "SIMPONI": 3.844948164872117, "ZOSTAVAX": 8.01080610508938}
\ No newline at end of file
+{"ANAKINRA": 506.1734940613872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4601.json
index 18b2755e815..2a3419139af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4601.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4601.json
@@ -1 +1 @@
-{"SOLIRIS": 64.26689007438506}
\ No newline at end of file
+{"ABACAVIR": 0.105658362800929, "ABRAXANE": 11.1327560184904, "ADCETRIS": 49.705165153382254, "AFINITOR": 0.2450603131331306, "ALEMTUZUMAB": 4.348995020437286, "ALIMTA": 11.926965603202683, "ALOXI": 7.775614210119801, "AMIKACIN": 2.0624746107322904, "APIXABAN": 0.1199808151399959, "APREPITANT": 0.8402505686556545, "ARAVA": 0.0329959499735409, "ARZERRA": 4.572052119832367, "ASPARAGINASE": 23.878899281226914, "ATAZANAVIR": 0.7949375226501213, "ATEZOLIZUMAB": 2.8199152235803773, "AVASTIN": 5.983756346775339, "AVELUMAB": 7.9766715281757135, "AXICABTAGENE": 7.587044907758247, "AZACITIDINE": 57.72506348179317, "BASILIXIMAB": 1.0735353583051763, "BEAM": 29.681723734005992, "BEVACIZUMAB": 7.7676878240503, "BLINATUMOMAB": 10.008951094035778, "BLINCYTO": 10.8561907412344, "BORTEZOMIB": 8.091478180854834, "BRENTUXIMAB": 22.86711427181714, "BUDESONIDE": 0.0885878328168076, "BUSILVEX": 11.183740004502177, "BUSULFAN": 18.70474644872796, "CABAZITAXEL": 19.02533671700152, "CABOMETYX": 0.2279758180790007, "CAELYX": 8.438589942503333, "CANCIDAS": 3.305773377064434, "CAPECITABINE": 2.503621248196435, "CARFILZOMIB": 6.066636984106319, "CARMUSTINE": 36.17453827670129, "CASPOFUNGIN": 5.0771209293157264, "CELLCEPT": 1.7275069248407249, "CETUXIMAB": 7.222634621859203, "CICLOSPORIN": 2.595967397286155, "CLADRIBINE": 22.613322623874133, "CLOFARABINE": 21.71906540082924, "CLOPIDOGREL": 0.1236763285564137, "COMIRNATY": 0.0047503476077919, "CRESEMBA": 9.188030188132352, "CYMBALTA": 0.0695681745896472, "CYRAMZA": 33.47390484485422, "CYTARABINE": 45.81071324906084, "DACOGEN": 17.857217806011302, "DARATUMUMAB": 7.012886842356283, "DARUNAVIR": 1.5710260795087383, "DARZALEX": 4.633424286719122, "DASATINIB": 2.202481132585026, "DECITABINE": 22.974699239047236, "DEFITELIO": 3.649380583156115, "DENOSUMAB": 2.286582056362342, "DEXAMETHASONE": 11.222189385718016, "DEXRAZOXANE": 17.89241831710447, "DOCETAXEL": 28.629989018094147, "DOXORUBICIN": 33.866760707716715, "DURVALUMAB": 19.157564658482517, "ELIQUIS": 0.0862721379240375, "EMEND": 1.948942866024692, "EPCORITAMAB": 16.946923541004338, "ERBITUX": 5.136998285102881, "ERIBULIN": 8.331747686386285, "ERLEADA": 1.442741094191144, "EXJADE": 1.024374958555707, "FASLODEX": 1.0088094889523544, "FENTANYL": 0.2268852760999373, "FILGRASTIM": 35.835060872544766, "FULVESTRANT": 1.9246870969330587, "GANCICLOVIR": 2.5514577489793666, "GAZYVARO": 3.821791946146434, "GLIVEC": 0.8678048838927409, "HALAVEN": 62.68894754290422, "HERCEPTIN": 7.358378751322185, "HYCAMTIN": 14.75578955889442, "HYDROCORTISONE": 0.5437824363474599, "IBRANCE": 2.506618236328081, "IBRUTINIB": 6.777115586950506, "IBUPROFEN": 0.2219051712643101, "ICLUSIG": 2.08746355379326, "IMATINIB": 3.062450639921827, "IMBRUVICA": 1.9161516994981955, "IMFINZI": 10.661499865196593, "IMNOVID": 5.969290767559164, "IPILIMUMAB": 0.5283217834723228, "IRESSA": 0.292591352733156, "IRINOTECAN": 14.530857300177512, "JAKAVI": 0.535888673219833, "JEVTANA": 85.26930555549139, 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1.243912660343028, "TAGRISSO": 0.4819421862005794, "TASIGNA": 0.2439559116061506, "TAXOTERE": 10.331509711212863, "TEGAFUR": 2.600021384872554, "TEMODAL": 4.228854622574868, "TEMOZOLOMIDE": 5.276576310830276, "TEMSIROLIMUS": 29.09691853793297, "THALIDOMIDE": 3.443644831636957, "THERAPEUTIC": 17.563989664438253, "THIOTEPA": 20.523005794198767, "TISAGENLECLEUCEL": 13.811249080970205, "TOPOTECAN": 80.62188377634364, "TORISEL": 2.395941843603665, "TRABECTEDIN": 10.616668020940304, "TRASTUZUMAB": 26.77580130996868, "TRISENOX": 3.919462467594223, "TRODELVY": 21.01203460348041, "VECTIBIX": 3.869850089455552, "VELCADE": 5.169660030664931, "VENCLYXTO": 7.490228400116724, "VENETOCLAX": 26.213232806241308, "VFEND": 0.5245032321491828, "VIDAZA": 22.154718997422755, "VORICONAZOLE": 1.593586586367398, "VYXEOS": 55.21249773350638, "XELODA": 4.032253310476976, "YESCARTA": 6.44990512549063, "YONDELIS": 11.031648660353635, "ZARZIO": 11.730560245907713, "null": 0.7452071410799019}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4602.json
index 469171f19dc..e06fdc7d653 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4602.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4602.json
@@ -1 +1 @@
-{"APREMILAST": 16.683504571789697, "ARANESP": 24.004628738543406, "ARIPIPRAZOLE": 2.778131293685698, "BUDESONIDE": 1.633428892331418, "ELIQUIS": 1.7680002707002536, "EMPAGLIFLOZIN": 10.507505644919796, "ENTRESTO": 1.596379138206012, "ENTYVIO": 7.687127818665867, "ESOMEPRAZOLE": 64.45286160110963, "FORSTEO": 1.6385104692576349, "GARDASIL": 2.7022190776147137, "HUMIRA": 5.088668436612184, "IBRANCE": 1.3150776709907874, "JAKAVI": 2.704818773691545, "NEXAVAR": 2.1646648075155395, "OPSUMIT": 2.4380643014211425, "PREGABALIN": 11.36202917709176, "STELARA": 1.2171778174157453, "XELJANZ": 1.002797136029678, "ZOSTAVAX": 1.572072561806486}
\ No newline at end of file
+{"HUMAN": 81.72025550461674, "PRIVIGEN": 317.6474411273187, "null": 2.524796588563209}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4603.json
index 6212883ef98..3b802717f01 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4603.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4603.json
@@ -1 +1 @@
-{"ADCIRCA": 11.765056782075728, "ADEMPAS": 12.131862212352932, "AFINITOR": 2.321564740074885, "AMBRISENTAN": 16.06189173093725, "AMINOSALICYLIC": 3.7543248014955513, "ARIPIPRAZOLE": 3.550384311307794, "BRAFTOVI": 3.648760396908065, "BRILIQUE": 6.693318509779702, "BUDESONIDE": 1.9785440498329248, "BUMETANIDE": 9.453690296989397, "BYETTA": 4.925895063485154, "CELLCEPT": 1.2287639652456366, "CIMZIA": 2.182474194863138, "CLOPIDOGREL": 4.456147188090807, "ELIQUIS": 5.350726431493227, "ENTRESTO": 1.0917620036607238, "ENTYVIO": 1.932435005826364, "EPADERM": 266.4204276526159, "EVISTA": 4.788631727801992, "FASLODEX": 2.583082491473178, "GARDASIL": 2.1084246897166388, "HUMIRA": 1.442820945651806, "IBRANCE": 1.105279551180431, "INSULIN": 1.9171405413709484, "JANUMET": 4.587561763338549, "JANUVIA": 2.7318980392954737, "LIXIANA": 11.553149135982896, "MICARDIS": 2.774504229906312, "MIRCERA": 7.847782481175907, "NPLATE": 2.9437158384846045, "OPSUMIT": 5.241081661584681, "PEGINTRON": 1.0825657385593908, "PLAVIX": 6.184302645079456, "PRADAXA": 16.168148586892954, "SPRYCEL": 2.633098621141812, "STELARA": 2.88500398146181, "TASIGNA": 3.205769918998977, "TICAGRELOR": 4.469980941847617, "TRACLEER": 1.940830947095056, "XARELTO": 8.015215115181691, "ZOSTAVAX": 3.61618860687412, "ZYPREXA": 2.342445791629729}
\ No newline at end of file
+{"ABILIFY": 0.5250088578617504, "ACETYLSALICYLIC": 81.33244164644749, "AFINITOR": 5.230201437869639, "AIMOVIG": 0.5173190374471066, "AMBRISENTAN": 6.791424561786785, "APIDRA": 2.200229058672741, "ARAVA": 0.9312398214663667, "ATRIPLA": 0.0595529433725172, "AUBAGIO": 1.2602575255157658, "BENLYSTA": 1.813597020208197, "BOSULIF": 3.0241784931202704, "BRAFTOVI": 3.285153783662985, "BRINTELLIX": 0.7404948333009465, "BUDESONIDE": 0.5982620484017742, "BYDUREON": 0.9061638801568556, "BYETTA": 0.7878159927906003, "CABOMETYX": 1.4544020355929652, "CELLCEPT": 0.6312025114617695, "CHAMPIX": 0.6104470773494032, "CIMZIA": 1.379277369760977, "CLOPIDOGREL": 1.3248154047765606, "COMIRNATY": 0.4151981049514226, "COSENTYX": 1.0335652233476584, "CYMBALTA": 0.9730540301608188, "DOCETAXEL": 0.6809116214190924, "DULOXETINE": 1.0850744190188386, "ELIQUIS": 0.3096411128494308, "ENBREL": 0.6570824581207612, "ESBRIET": 2.586965187055508, "EXJADE": 0.6170479615486613, "FASLODEX": 1.1713436220603743, "FIRDAPSE": 3.548973781086381, "FORSTEO": 2.338893675408068, "FORXIGA": 0.7684035497268347, "FULVESTRANT": 2.369405155760438, "GARDASIL": 0.4523911728247432, "HARVONI": 1.4691320698760717, "HUMALOG": 2.239580433468652, "HUMIRA": 0.601549941796605, "IBRANCE": 2.9073050177231123, "INLYTA": 4.713536244005971, "IRESSA": 1.5577270224193558, "JANUMET": 1.0730401667893592, "JANUVIA": 0.8409240046310164, "JARDIANCE": 1.1385783818586102, "KEPPRA": 1.6847851747748268, "KEYTRUDA": 2.406856074628886, "LANTUS": 0.8460806533634684, "LATUDA": 0.9317460778806432, "LEVEMIR": 0.7382610627806404, "LEVETIRACETAM": 0.4634697267982551, "LONSURF": 2.7428534297056557, "LYNPARZA": 2.3676459474474, "LYRICA": 0.7540122264858646, "MEKINIST": 1.3824538181918902, "MELATONIN": 3.119725725784809, "MEPOLIZUMAB": 5.222092405354624, "METHOTREXATE": 0.8946010563300242, "NEULASTA": 1.1106874533600424, "NEXAVAR": 1.267091223151776, "NUCALA": 0.600514387574761, "OFEV": 1.4485797735974868, "OPDIVO": 0.5726202434388865, "OPSUMIT": 0.4565590961767922, "PANTOPRAZOLE": 1.1277850853305909, "PEGASYS": 1.2676870072075406, "PEGINTRON": 2.0230253038636388, "PLAVIX": 0.7598692444504069, "ROTATEQ": 1.3082214269973922, "RYBELSUS": 2.99146242080054, "SAXENDA": 1.8908165738510696, "SHINGRIX": 0.7315991211111484, "SIMPONI": 0.3999098756794061, "SOLIRIS": 0.5332824926811708, "SPIKEVAX": 0.6919054148268655, "SPINRAZA": 1.9502110327793871, "SPRYCEL": 0.8173876511882813, "STALEVO": 2.8815379729520307, "STELARA": 0.4459263871730022, "STIVARGA": 1.602241535919579, "STRIBILD": 0.3347780257137607, "SUBOXONE": 0.5772193369165846, "SUTENT": 6.76616756268536, "SYNAGIS": 4.40225001172453, "TAGRISSO": 3.094787333093971, "TASIGNA": 0.6004146744523212, "TEDUGLUTIDE": 22.883103439136296, "TOZINAMERAN": 1.6362087873697908, "TRELEGY": 1.1325204475188098, "TRULICITY": 10.424494113627816, "TRUVADA": 0.1809285333394805, "VAXZEVRIA": 0.4214385613759797, "VFEND": 1.1018564740997707, "VICTOZA": 0.9471652801573563, "VOTRIENT": 2.011874490830634, "XALKORI": 3.2814206874155505, "XELJANZ": 0.7336451998561127, "XTANDI": 2.511557472977726, "ZOSTAVAX": 0.6509102820103284, "ZYPREXA": 0.408652395504013, "null": 0.8762732043712969}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4604.json
index 48c47452e6a..bca42395644 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4604.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4604.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 68.73750605881673, "null": 1.0958848707825044}
\ No newline at end of file
+{"COMIRNATY": 0.8989936246035998, "null": 1.0406871608114707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4605.json
index 1272b17c853..72bbb9f872a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4605.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4605.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 25.589993467539543, "ARANESP": 11.939888168039078, "CICLOSPORIN": 5.160554024960483, "EXJADE": 144.148417187257, "JAKAVI": 21.958596629761185, "PEGASYS": 3.2150869425324564, "SOLIRIS": 32.60414501583814}
\ No newline at end of file
+{"null": 1.0987122816961326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4606.json
index 9c92b56a41e..fcba581f239 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4606.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4606.json
@@ -1 +1 @@
-{"TOZINAMERAN": 1.9107512668070128, "null": 1.7719329790370446}
\ No newline at end of file
+{"ABACAVIR": 0.0795868700736113, "ABASAGLAR": 2.0871794255666787, "ABATACEPT": 0.0473755479232129, "ABILIFY": 1.4837017180940102, "ACE": 5.1820830493482335, "ACTOS": 0.7640354448863972, "ADALIMUMAB": 0.0577564996854008, "ADCIRCA": 2.0239699340449557, "ADEMPAS": 1.3495488885069995, "AERIUS": 0.618716837288007, "AFINITOR": 0.8468899541996078, "AIMOVIG": 1.628156079040279, "ALEMTUZUMAB": 0.9512897995528328, "ALL": 0.8610601074105051, "AMBRISENTAN": 2.373964673760112, "ANAKINRA": 2.190436924521276, "ANORO": 0.2836387425658651, "APIDRA": 1.9552328218014048, "APIXABAN": 2.4014769143065764, "APROVEL": 0.487345875439306, "ARANESP": 0.3965517003104914, "ARAVA": 0.1825454937524066, "ARIPIPRAZOLE": 0.5759005099697498, "ATRIPLA": 0.0242041102100755, "AUBAGIO": 1.2129847139309833, "AVAMYS": 0.5934190911460471, "AVANDIA": 0.1050413338001191, "AVASTIN": 0.1428987503739736, "AVONEX": 1.3915473863740793, "AZATHIOPRINE": 0.3440170430248248, "BENLYSTA": 1.700376571995112, "BETAFERON": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4607.json
index cbb3e6661a8..8f4c780e7a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4607.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4607.json
@@ -1 +1 @@
-{"null": 1.0405878588518898}
\ No newline at end of file
+{"ABILIFY": 0.1193358722656014, "ACLASTA": 3.069383043430526, "ADCIRCA": 1.7325842154977042, "AFINITOR": 0.1634435085845243, "AIMOVIG": 0.6431997240261044, "ALEMTUZUMAB": 0.4775565122571122, "AMBRISENTAN": 1.1201921707542308, "APIDRA": 0.6734606175733894, "ARAVA": 0.0355374568511158, "AUBAGIO": 0.3047744943701715, "AVANDIA": 0.0877283691054751, "AVASTIN": 0.2139079721128805, "BENLYSTA": 0.4376455555959872, "BETAFERON": 0.5928556730688319, "BRILIQUE": 0.396628735706041, "BRINTELLIX": 0.4215462524376076, "BRIVIACT": 0.6767744959423058, "BUDESONIDE": 0.4003972949841251, "BUPRENORPHINE": 0.4432900940056394, "BYDUREON": 1.4816407931835591, "BYETTA": 0.2002974691438261, "CHAMPIX": 0.9647051362560763, "CIMZIA": 0.0598454239844697, "CLOPIDOGREL": 0.2469702877572054, "COMIRNATY": 1.848632532332231, "COSENTYX": 0.1551991121752307, "CYMBALTA": 0.4489467282381182, "EDOXABAN": 6.567110249670703, "ELIQUIS": 0.2229354330488767, "ELLAONE": 1.360883030988104, "EMTRICITABINE": 0.8467131489588571, "ENBREL": 0.2551858805907923, "ENTRESTO": 0.1174304122140387, "ENTYVIO": 0.3120967518648824, "ESBRIET": 0.5738344116585328, "EXFORGE": 0.4440337852823655, "FAMPYRA": 0.853532428996832, "FASENRA": 0.7732150798087991, "FASLODEX": 0.2976898318878892, "FENTANYL": 0.2188936681044025, "FIRDAPSE": 2.938477271034456, "FLEBOGAMMA": 8.577465019364762, "FORSTEO": 1.033708046813737, "FORXIGA": 0.4614445370710044, "FULVESTRANT": 0.3305233251856017, "GARDASIL": 1.2032233557047494, "HERCEPTIN": 0.5094617028896649, "HIZENTRA": 0.3552298402687732, "HUMALOG": 0.228165271382744, "HUMAN": 0.3395850436457507, "HUMIRA": 0.1207648962066939, "HYDROCORTISONE": 2.535180435375461, "IBRANCE": 0.6662703887861701, "IBUPROFEN": 0.1273599141413372, "INLYTA": 0.2301859010770248, "INSULIN": 0.2626332640279062, "JAKAVI": 0.1570455890971921, "JANUMET": 0.153294625896259, "JANUVIA": 0.2137368742602691, "JARDIANCE": 0.1482400814517807, "KEPPRA": 0.0802986628328265, "KESIMPTA": 1.9594674085924828, "KEYTRUDA": 0.2274041840400274, "KIOVIG": 3.387153975982057, "LANTUS": 0.2995552856334511, "LEMTRADA": 0.5222186290117271, "LEVETIRACETAM": 0.1493155031340463, "LEVODOPA": 1.290447701128553, "LEVOFLOXACIN": 0.1304279789999011, "LYRICA": 0.3534908871747529, "MEKINIST": 0.2110814443889645, "METHOTREXATE": 0.1726568264720689, "MMRVAXPRO": 0.1506989737679152, "MODERNA": 0.6012173186322983, "NAGLAZYME": 0.9569301847794686, "NEXAVAR": 0.1649718249323814, "NIMENRIX": 1.2961235217522336, "NUCALA": 0.296317508144548, "OCRELIZUMAB": 4.244807473350331, "OLANZAPINE": 0.131869658774203, "OMALIZUMAB": 0.2856216405479822, "OPSUMIT": 0.2198831159277465, "PEGASYS": 0.5840419955675091, "PEGINTRON": 0.4914329375361702, "PLAVIX": 0.218592684365742, "PLEGRIDY": 1.088500050446459, "PREGABALIN": 1.0459751874797936, "PRIVIGEN": 2.4748199754276072, "REBETOL": 0.6759835183813738, "RINVOQ": 0.2856054854621066, "RITUXIMAB": 0.1424653047505628, "ROACTEMRA": 0.2414046010481445, "SAXENDA": 0.364921727696384, "SHINGRIX": 1.7570035979177607, "SIMPONI": 0.2605683403250762, "SOLIRIS": 0.11978395346674, "SPIKEVAX": 1.7861298182021632, "SPRYCEL": 0.1835982743358255, "STELARA": 0.6427919337427392, "SUBOXONE": 0.2145406802061322, "SUTENT": 0.7253855981240839, "TAMIFLU": 0.1577082738318521, "TASIGNA": 0.3440832552990837, "TOZINAMERAN": 2.219087392015064, "TRULICITY": 0.2424279057004376, "TWINRIX": 0.758163413283311, "VAXZEVRIA": 5.353143648973064, "XELJANZ": 0.2579395206555862, "XELODA": 0.8903252369466218, "XOLAIR": 0.3003497702948376, "XTANDI": 0.3232267738879811, "ZOSTAVAX": 0.1183699037865871, "ZYPREXA": 0.0618017466481491, "null": 0.3969915394130893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4608.json
index b21d4e555f2..0eec1ddc30e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4608.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4608.json
@@ -1 +1 @@
-{"ABILIFY": 6.647982920703926, "AERIUS": 1.3432511090410035, "AIMOVIG": 1.7798108209657917, "ANTIBIOTICS": 2.3182879642361813, "ARIPIPRAZOLE": 4.686009930732643, "BEDAQUILINE": 1.476372424064882, "BENZODIAZEPINE": 1.7498453509839649, "BEXSERO": 10.749402520194906, "BIKTARVY": 1.3986770159035622, "BRINTELLIX": 5.672481692463814, "BRIVARACETAM": 9.979120438565484, "BRIVIACT": 11.55014830485317, "BUPRENORPHINE": 1.741075296774277, "CAFFEINE": 6.626050056784711, "CHAMPIX": 10.080761153280072, "CIRCADIN": 3.2313247085520844, "COMTAN": 2.936880922987732, "CYMBALTA": 19.78671887651882, "DAKLINZA": 2.889726209090952, "DULOXETINE": 2.4445471083525523, "EFAVIRENZ": 1.2267445028806894, "ENTACAPONE": 4.337991242353828, "EPCLUSA": 1.089330195072882, "EPIDYOLEX": 9.332812909565618, "FYCOMPA": 23.393412907221617, "HEMANGIOL": 11.936885285375954, "HEXACIMA": 15.450146402249551, "HEXYON": 7.458123195875359, "INCIVO": 1.5047412779950171, "INFANRIX": 18.34744521629333, "INTRONA": 3.725918475816112, "IRON": 1.3885161902585537, "ISENTRESS": 1.0118719153105835, "KAFTRIO": 4.920430549778263, "KEPPRA": 7.34318230157772, "LACOSAMIDE": 2.7945336759756816, "LATUDA": 3.546732087007208, "LEVETIRACETAM": 7.3781793056509715, "LEVODOPA": 3.0533610105981435, "LURASIDONE": 5.09276508583079, "LYRICA": 1.0214771381618668, "MELATONIN": 2.756344921358165, "MENVEO": 3.849798913321313, "MMRVAXPRO": 4.687593131372768, "NALOXONE": 9.067195014530611, "NIMENRIX": 1.9777968445351648, "OLANZAPINE": 2.665301663549413, "OLYSIO": 2.3920423296030413, "PEGASYS": 5.051250139894244, "PEGINTERFERON": 2.3774481633318847, "PEGINTRON": 3.651052494354712, "PERAMPANEL": 17.189651770743307, "PREGABALIN": 1.253612250103385, "PREVENAR": 9.285284864811803, "REBETOL": 2.274703117893857, "RIBAVIRIN": 1.8666174205925952, "RISPERIDONE": 2.9416183713819666, "ROTATEQ": 14.852874171118836, "RYEQO": 6.512521867210966, "SLENYTO": 30.747741661972785, "SOVALDI": 1.142257657352516, "SUBOXONE": 2.823047324388566, "SYNAGIS": 3.815588419976157, "TAMIFLU": 1.2006181139233036, "TESTOSTERONE": 1.306903195431084, "TRIUMEQ": 2.5452460949243254, "VARENICLINE": 9.441155517020963, "VIMPAT": 4.579458755173473, "VORTIOXETINE": 17.816496575289133, "WAKIX": 8.507842657057793, "XYREM": 4.259291997258726, "ZEPATIER": 2.3672451513448864, "ZYPADHERA": 1.8830692736227663, "ZYPREXA": 1.1319420863947285, "null": 1.5585766937947796}
\ No newline at end of file
+{"ATRIPLA": 0.4265094704341512, "BRINTELLIX": 2.599679390686197, "CHAMPIX": 3.878582112330203, "COMIRNATY": 0.7919182025296528, "CYMBALTA": 1.766297086492456, "FORSTEO": 1.3754843046499403, "GARDASIL": 0.6072394709278909, "HUMALOG": 0.635257018382257, "KEPPRA": 3.2270484088857145, "LYRICA": 6.431042855590051, "PEGASYS": 0.4928183041916412, "PREGABALIN": 3.0867872058919037, "SPIKEVAX": 0.5593052998498595, "TOZINAMERAN": 1.5509013583675155, "VAXZEVRIA": 0.7824890238595009, "VIMPAT": 3.626686513189072, "XYREM": 9.496381190061712, "ZYPADHERA": 23.81473364229841, "ZYPREXA": 1.9705630615999392, "null": 1.7752219006305838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4609.json
index 900c55cc790..f6b3164903c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4609.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4609.json
@@ -1 +1 @@
-{"BEXSERO": 18.888237832198858, "INFANRIX": 17.769163721857655, "MMRVAXPRO": 593.8582125548261, "PREVENAR": 29.0074078727816, "ROTATEQ": 2.4578526523356543, "null": 1.4782030733444094}
\ No newline at end of file
+{"ABILIFY": 10.537810117099314, "ARIPIPRAZOLE": 9.989508817217072, "CHAMPIX": 7.449904340325764, "DULOXETINE": 19.140028951227123, "OLANZAPINE": 13.110535302706676, "SUBOXONE": 12.732692712441128, "null": 1.9100447267473757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/461.json
index 9e73f2c5261..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/461.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/461.json
@@ -1 +1 @@
-{"EYLEA": 92.54339094341348, "null": 5.177702854182607}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4610.json
index f0ecebbbcf7..513d649ba86 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4610.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4610.json
@@ -1 +1 @@
-{"ABATACEPT": 28.4834974701842, "ACETAMINOPHEN": 51.21877906216128, "ACTOS": 5.018076396068219, "ADALIMUMAB": 10.958487464663094, "AIMOVIG": 2.018269559401185, "APREMILAST": 1.5029437112780772, "APREPITANT": 12.84806847105128, "ARAVA": 7.768570336147479, "CHLORHEXIDINE": 78.50191678620189, "CIMZIA": 29.22903886591617, "COSENTYX": 1.049091764713718, "ERELZI": 11.061700721941204, "GARDASIL": 2.4528970980124982, "HARVONI": 1.5072052750318543, "JANUVIA": 1.272284663079558, "RITUXIMAB": 1.4781987370754464, "ZOSTAVAX": 1.9066338067816515}
\ No newline at end of file
+{"ABILIFY": 0.1677726279548176, "ADALIMUMAB": 0.1005317967372271, "ADEMPAS": 0.6401441702655437, "ADENURIC": 0.6876022502466803, "AERIUS": 0.7022845870499453, "AFINITOR": 0.2292610755367621, "AIMOVIG": 1.0968922563888963, "ALEMTUZUMAB": 0.4986973913502301, "ALIMTA": 0.2023885617920024, "AMINOSALICYLIC": 0.6948060561915514, "APIDRA": 0.6917248493634616, "APIXABAN": 0.1643549237212215, "ARAVA": 0.0823669738679448, "ARIPIPRAZOLE": 0.1385126062547426, "ATRIPLA": 0.0119711020425933, "AUBAGIO": 0.4156279468786534, "AVAMYS": 0.267316807722786, "BENLYSTA": 0.9788403227061624, "BETMIGA": 0.5251787296054434, "BEXSERO": 0.671780126393218, "BONVIVA": 0.4588074502555085, "BRILIQUE": 0.1537880092434827, "BRINTELLIX": 0.6532690156098977, "BUDESONIDE": 0.2006188024605658, "BUPIVACAINE": 0.6630584526293506, "BUPRENORPHINE": 0.1786830902423715, "BYDUREON": 0.6826830435670219, "BYETTA": 0.091819840268749, "CABOTEGRAVIR": 2.3383451361351115, "CAELYX": 2.12627571503587, "CELLCEPT": 0.0735667676016638, "CHAMPIX": 0.3104039191386103, "CICLOSPORIN": 0.0530845088739271, "CIMZIA": 0.1221709072079859, "CLOPIDOGREL": 0.1744529485455013, "COMIRNATY": 2.70154254566016, "COSENTYX": 0.4261482056422391, "CYMBALTA": 0.463749961945726, "CYTARABINE": 0.1664103444373365, "DARZALEX": 0.4018193513472528, "DESLORATADINE": 1.1927084958722949, "DEXAMETHASONE": 0.2396578210271424, "DOCETAXEL": 0.3477075828623071, "ELIQUIS": 0.2071307721995632, "EMEND": 1.4196423410860195, "ENBREL": 0.2857506096348295, "ENOXAPARIN": 0.3350616080735212, "ENTRESTO": 0.1286779716571663, "ENTYVIO": 0.5378782590392287, "ESBRIET": 0.3475884917942072, "EVENITY": 0.3404485898619718, "EVISTA": 0.2933276495531784, "EXFORGE": 0.8591630273838007, "FAMPYRA": 0.4835888690924329, "FASENRA": 0.7910420755131324, "FASLODEX": 0.5130476107534272, "FENTANYL": 0.5541651018453989, "FLEBOGAMMA": 2.224037535126375, "FLUCELVAX": 2.1143979841978284, "FORSTEO": 0.8091027038987633, "FORXIGA": 0.2774397168323911, "GARDASIL": 0.8763567760359101, "GAZYVARO": 1.0288551902951544, "HIZENTRA": 0.7105083812384562, "HUMALOG": 0.1979583119642736, "HUMIRA": 0.4388077870751612, "HYDROCORTISONE": 0.6782573262142589, "IBRANCE": 0.3199409415794472, "IBUPROFEN": 0.6634284013862373, "INCIVO": 0.2780524108746329, "INFLIXIMAB": 0.8908990014611722, "INSULIN": 0.1455629588756166, "JANUMET": 0.1437270473498944, "JANUVIA": 0.0870277282861816, "JARDIANCE": 0.1305767889349495, "JCOVDEN": 4.221991613809632, "JEVTANA": 0.6801140035064305, "KEPPRA": 0.2183601631962711, "KESIMPTA": 0.6182624137554843, "KEYTRUDA": 0.0997555041820244, "KIOVIG": 1.378494388532437, "KISQALI": 0.3151134617813556, "LANTUS": 0.4523821400647576, "LATUDA": 0.4262221904357323, "LEFLUNOMIDE": 0.3996373451106611, "LEMTRADA": 1.2038659933126423, "LEVEMIR": 0.2044652641095103, "LEVOFLOXACIN": 0.1877918264331452, "LIXIANA": 0.3726887239715832, "LYNPARZA": 0.3036331792646729, "LYRICA": 0.3970483575675592, "MAVENCLAD": 0.7216526964762112, "MENVEO": 1.757856042277869, "MEPOLIZUMAB": 0.1223775162790406, "METHOTREXATE": 0.3653591324872972, "MICARDIS": 0.3269866626835888, "MIDAZOLAM": 0.1955936447579894, "MIRCERA": 3.396729513191999, "MIRVASO": 9.760374108496348, "MMRVAXPRO": 0.2763467245644856, "MODERNA": 0.4357333802743196, "NAGLAZYME": 0.4699644212228052, "NEULASTA": 0.7146442753880122, "NEXAVAR": 0.2959406043192893, "NIMENRIX": 1.4005894742790674, "NUCALA": 0.251600927334273, "OCRELIZUMAB": 1.0963636139098765, "OMALIZUMAB": 0.8454695607926905, "OPSUMIT": 0.3330375556145815, "OXYBUTYNIN": 0.711138528991459, "PANTOPRAZOLE": 1.406468258293759, "PEGASYS": 0.2898741751177642, "PEGINTRON": 0.2319330999396932, "PERJETA": 1.0403332027763617, "PLAVIX": 0.1665974961471091, "PLEGRIDY": 0.7689490078181035, "PREVENAR": 0.5160729650267375, "PRIVIGEN": 0.7340143689917793, "QUTENZA": 4.250103619096478, "RASILEZ": 0.3588192246713452, "RELVAR": 0.5702289144819012, "REMICADE": 0.3488450565232474, "REVATIO": 0.6880971740041366, "RINVOQ": 0.3526082538411367, "RITUXIMAB": 0.1977432874883493, "RIXATHON": 2.8585958553710897, "ROACTEMRA": 0.7802759338759973, "SHINGRIX": 1.773998004328363, "SILDENAFIL": 0.4000331943745717, "SIMPONI": 0.2472904296101645, "SKYRIZI": 0.8249526809183233, "SOVALDI": 0.328846413634252, "SPIKEVAX": 3.1671436873062917, "SPINRAZA": 0.2766160803144771, "STELARA": 0.4336338234988149, "SUBOXONE": 0.3671502867474254, "SUTENT": 0.2927608342203528, "TAMIFLU": 0.1261593365827704, "TOZINAMERAN": 2.104882907557666, "TRACLEER": 0.1341944806154157, "TRELEGY": 0.2204888034951361, "TRULICITY": 0.2183246527596043, "TWINRIX": 1.2668994759257073, "VAXZEVRIA": 1.9209381829898808, "VIAGRA": 1.1093074803370897, "VOTRIENT": 0.28690107441597, "XELJANZ": 0.3881762699048481, "XOLAIR": 0.978777166290928, "XTANDI": 0.2005532849731099, "ZARZIO": 1.813191045439557, "ZOSTAVAX": 0.29418561772728, "null": 0.5571315223159716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4611.json
index 9a53c747980..bf7e3bb757a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4611.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4611.json
@@ -1 +1 @@
-{"AVANDAMET": 10.738798988022532, "AVANDIA": 11.298375858973191, "BUPIVACAINE": 6.122132805346811, "CLOPIDOGREL": 2.2545682429866, "ELIQUIS": 2.076278699212947, "FENTANYL": 1.1947223640906202, "IBUPROFEN": 2.380382687382895, "LACOSAMIDE": 6.019949753652213, "NOVOSEVEN": 16.876166078491035, "PLAVIX": 1.3874438141587089, "RASILEZ": 7.462843935712358, "TASIGNA": 7.443940733897348, "VOTRIENT": 1.6599043375148834, "null": 1.5133796784920477}
\ No newline at end of file
+{"AIMOVIG": 1.0136780318336762, "ARAVA": 0.5354173489776405, "ATAZANAVIR": 8.56573813086154, "BUDESONIDE": 0.8969487012857972, "BYDUREON": 1.821698789600838, "BYETTA": 4.095411907402606, "CELECOXIB": 10.70415470702378, "CHAMPIX": 1.537711238864055, "CIMZIA": 0.4473451856777438, "COMIRNATY": 0.4527852465091001, "CYMBALTA": 2.2661541443277966, "DEXAMETHASONE": 1.3332592734286437, "ELIQUIS": 0.4107929398821042, "FENTANYL": 0.8523543298241725, "HUMALOG": 0.8340142771733309, "IBRANCE": 0.5185213649045461, "JANUMET": 1.2692692341986138, "JARDIANCE": 0.91016978723879, "LANTUS": 0.7268431842300193, "LATUDA": 4.893955864089135, "OCRELIZUMAB": 2.538808805793816, "OLANZAPINE": 1.3856534123351478, "PEGASYS": 0.948373402435172, "SPIKEVAX": 0.4436928748022332, "SUBOXONE": 2.551223370767334, "TOZINAMERAN": 0.9421375219271012, "VAXZEVRIA": 0.2892357003979747, "XTANDI": 1.651195942958103, "XYREM": 23.63650974650078, "ZYPREXA": 0.9102893736253208, "null": 2.2530533052906696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4612.json
index e2b33086179..b24066411f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4612.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4612.json
@@ -1 +1 @@
-{"AVANDAMET": 169.05160863372032, "AVANDIA": 234.05620985013016, "BRILIQUE": 5.461943434486682, "CLOPIDOGREL": 3.988724709882757, "DASATINIB": 27.773926467812952, "ELIQUIS": 1.1681929170400824, "ENTRESTO": 19.16912200475098, "GLIBENCLAMIDE": 19.06529631221713, "PLAVIX": 1.828061924812757, "TASIGNA": 4.209436227066488, "VALSARTAN": 15.20171955356789}
\ No newline at end of file
+{"AUBAGIO": 0.5817199531569962, "BYDUREON": 1.3587584914363502, "CHAMPIX": 0.874502105286078, "COMIRNATY": 2.27589341493353, "CYMBALTA": 0.7272077815394915, "ESOMEPRAZOLE": 2.5296386458452327, "FORSTEO": 0.4235094817217616, "GARDASIL": 1.7261195829621807, "HYDROCORTISONE": 1.3463381258547438, "IBRANCE": 0.3498849755706369, "NIMENRIX": 2.3880433608597538, "OCRELIZUMAB": 3.657937578654438, "PEGASYS": 0.4547449096061266, "PEGINTRON": 0.3644453925300641, "SHINGRIX": 0.6997964138645407, "SPIKEVAX": 1.8953810326240887, "STELARA": 0.6987291700770873, "SUBOXONE": 5.806096060797016, "TOZINAMERAN": 3.948934846546209, "VAXZEVRIA": 3.850049122266809, "XELJANZ": 0.3249900099467798, "ZOSTAVAX": 0.5050731794706149, "null": 0.341082859893982}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4613.json
index 8e612627f5c..f33523fb502 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4613.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4613.json
@@ -1 +1 @@
-{"COMIRNATY": 1.940416312592749, "CYMBALTA": 2.622123333564804, "ELIQUIS": 4.971902340279449, "EVENITY": 22.582858916587057, "SPIKEVAX": 1.16147089474871}
\ No newline at end of file
+{"ABILIFY": 4.052039841038141, "BRINTELLIX": 5.15906391419491, "CHAMPIX": 10.6610848793209, "CIALIS": 34.36296800537022, "COMIRNATY": 0.6288953040785863, "CYMBALTA": 4.166641984353347, "FAMPYRA": 5.179075140702104, "HUMIRA": 2.483308339843104, "LATUDA": 10.379118698451762, "LEVETIRACETAM": 2.139695809851041, "PEGASYS": 1.0775117859063037, "SPIKEVAX": 0.5167137316609, "SUBOXONE": 2.191718495826146, "TOZINAMERAN": 0.4655924961953015, "VAXZEVRIA": 0.645070953783854, "ZYPREXA": 1.5766196217330264, "null": 1.732392109344057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4614.json
index 7efa8018aa3..7775518db0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4614.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4614.json
@@ -1 +1 @@
-{"null": 3.5148518229747605}
\ No newline at end of file
+{"CHAMPIX": 11.54939764678119, "POPPERS": 8195.362592278176, "PTC": 6189.007009624309, "VAXZEVRIA": 0.4521648676685955, "null": 1.1528510892854449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4615.json
index d28f451922c..15d067fcf5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4615.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4615.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 13.578741053825404, "ENTRESTO": 10.09415479386784, "JEVTANA": 43.06972406313073, "null": 1.3510245910778522}
\ No newline at end of file
+{"CHAMPIX": 8.168554746748166, "null": 3.481905220782889}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4616.json
index e7fa9230e82..94a1caebc84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4616.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4616.json
@@ -1 +1 @@
-{"COVID19": 2.8988850749334607}
\ No newline at end of file
+{"SIMPONI": 72.91188094610021}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4617.json
index 3c96b47ceb8..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4617.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4617.json
@@ -1 +1 @@
-{"ALIMTA": 2.3104260269948287, "APIXABAN": 1.0568753804632258, "ARANESP": 1.6180716176340135, "AVANDAMET": 2.4155015201814027, "AVANDIA": 3.742709476090834, "AVASTIN": 1.6852805213405195, "BIKTARVY": 1.0762717647756663, "BRILIQUE": 3.3788468281178163, "CELECOXIB": 1.5900960339123278, "CELSENTRI": 13.789760203676, "CLOPIDOGREL": 2.480939968419201, "COMIRNATY": 1.3340732847253094, "DAPAGLIFLOZIN": 15.316692373302043, "EDOXABAN": 17.24953900233806, "ELIQUIS": 14.237270524511388, "ENOXAPARIN": 2.041325858046412, "ESOMEPRAZOLE": 6.762726789423836, "EVENITY": 2.5693306780159952, "EVISTA": 3.822416497238737, "EXFORGE": 1.03072634578848, "EYLEA": 5.0471871161541735, "FAMPYRA": 1.3268394288959828, "FASLODEX": 1.1915776719542233, "FORXIGA": 3.390414864013496, "HUMAN": 2.221641593992576, "ICLUSIG": 9.488444658453872, "INLYTA": 1.4448061770306078, "INSULIN": 1.2597515361290428, "IRBESARTAN": 1.638573814948889, "LENVIMA": 1.588838280199629, "LIXIANA": 9.215540370567451, "MICARDIS": 1.8731534963608945, "NILOTINIB": 5.555166720576056, "NOVOSEVEN": 14.52672044546472, "NPLATE": 2.3602931562124865, "OFEV": 1.5304777585349398, "PLAVIX": 5.542897982559905, "PRADAXA": 4.107753456623793, "PRAXBIND": 24.57065142055085, "RINVOQ": 1.513944949805987, "ROACTEMRA": 1.5535094713251325, "SILDENAFIL": 3.8034227662386986, "STELARA": 1.1331011230028372, "TASIGNA": 4.655592818252318, "VAXZEVRIA": 1.4985023208434367, "VIAGRA": 1.3981915853893057, "VOTRIENT": 1.4616262290287374, "XARELTO": 8.512942910284098, "ZOSTAVAX": 2.3377378250285927}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4618.json
index 7371bc496fb..5aabf5a0255 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4618.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4618.json
@@ -1 +1 @@
-{"SPIKEVAX": 2.00187227119521}
\ No newline at end of file
+{"ADALIMUMAB": 23.686914805053664, "ALIGN": 297.0486247413064, "AMINOSALICYLIC": 169.4551418725758, "AVAMYS": 85.72000855297307, "AVASTIN": 6.248840626523406, "BUDESONIDE": 137.9401832500308, "ENTYVIO": 2.0973478190704777, "KEYTRUDA": 2.490888177887532, "LENVIMA": 4.233363004187082, "PREGABALIN": 45.696109829174965, "STELARA": 1.5522942159943858, "null": 0.0628198009276522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4619.json
index b16ace59768..70732e55a65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4619.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4619.json
@@ -1 +1 @@
-{"AUBAGIO": 93.99684932207109, "ENTYVIO": 37.41776843719308}
\ No newline at end of file
+{"null": 3.5688784736225214}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/462.json
index 443820571a4..1429ecd06bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/462.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/462.json
@@ -1 +1 @@
-{"BEOVU": 1576.6926865036194, "BROLUCIZUMAB": 402.1795221334658, "EYLEA": 113.57051882361128, "LEVOFLOXACIN": 14.988135685507585}
\ No newline at end of file
+{"COMBIVIR": 229.0867695823449, "NEXAVAR": 70.07344786311162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4620.json
index 083fab6d87f..83636fc6bf8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4620.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4620.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 87.05177335830737, "AUBAGIO": 7.22793913717343, "AZACITIDINE": 47.00734851353359, "BENLYSTA": 10.913633692233969, "BUSULFAN": 40.178881316155525, "CARFILZOMIB": 176.87886588837085, "CARMUSTINE": 126.61304747228668, "CELLCEPT": 18.16431770930829, "CICLOSPORIN": 11.759142589694063, "EPIVIR": 38.38209824326554, "RITUXIMAB": 18.671698031993053}
\ No newline at end of file
+{"COMIRNATY": 0.952630853258439, "JARDIANCE": 30.952642667395857, "null": 0.6264936854158752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4621.json
index 5700f821143..7ae1c99f27e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4621.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4621.json
@@ -1 +1 @@
-{"null": 5.731858389088097}
\ No newline at end of file
+{"null": 1.6892141769044025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4622.json
index 809b51d385c..5ae7692b17b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4622.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4622.json
@@ -1 +1 @@
-{"AERIUS": 1.615959876585364, "ALOXI": 15.536059121445389, "AMIKACIN": 1.8506792590522805, "APROVEL": 2.692949878694765, "APTIVUS": 19.5686164861567, "ASPARAGINASE": 2.2099360541617314, "ATAZANAVIR": 12.434209205190912, "ATEZOLIZUMAB": 2.472686665377009, "AVANDIA": 1.6282480843982647, "AVASTIN": 1.3748688616834654, "AZATHIOPRINE": 1.4506319533233352, "BARACLUDE": 4.588502279679656, "BETAFERON": 2.5575392497411418, "BIKTARVY": 1.1285910685454168, "BYETTA": 1.638999834802348, "CABOMETYX": 1.1547157230115643, "CANCIDAS": 2.147810521158517, "CASPOFUNGIN": 1.7495828733592147, "CELSENTRI": 5.3434896740701445, "CICLOSPORIN": 1.0511506985155794, "COAPROVEL": 1.1779540068986325, "COMBIVIR": 7.379535794035868, "CRIXIVAN": 5.572587602303014, "CUBICIN": 1.203771769906719, "CYMBALTA": 1.0533298036790515, "DAKLINZA": 3.660378907569706, "EBIXA": 2.302326844018302, "EFAVIRENZ": 2.839182166134649, "EMTRICITABINE": 1.705589941716707, "ENTECAVIR": 5.625254493717801, "EPIVIR": 2.042905083610589, "ERBITUX": 1.7827147435367316, "ESOMEPRAZOLE": 1.1692585585177724, "EUCREAS": 4.055669878212297, "EXJADE": 3.448022727741748, "EXVIERA": 27.597928530877887, "FEBUXOSTAT": 2.659373579356497, "FUZEON": 13.111238054977, "GALVUS": 5.058606614424945, "GANCICLOVIR": 1.1752540264663058, "GLIVEC": 1.1722431849771353, "HARVONI": 2.213216338336152, "HEPSERA": 3.5537000308467173, "HUMAN": 1.791547673267337, "IBUPROFEN": 1.8174018399560967, "INCIVO": 1.481915220059996, "INTRONA": 3.0423533520306183, "INVIRASE": 4.303744149156755, "IRBESARTAN": 1.9668285069887572, "ISENTRESS": 3.0506423672595133, "JAKAVI": 1.76571377210219, "JANUMET": 1.4156464610662969, "JANUVIA": 1.421990469535472, "KALETRA": 4.996178392122745, "KETEK": 13.372204526990384, "KISQALI": 2.493529651810884, "KIVEXA": 6.632792584050142, "LAMIVUDINE": 7.19710398418993, "LEMTRADA": 1.0028659948625036, "LENVIMA": 3.657477694873463, "LEVOFLOXACIN": 1.2430494941833052, "LONSURF": 2.7572258199978266, "LUTATHERA": 2.697811465500182, "MERCAPTOPURINE": 4.162901294072843, "MICARDIS": 4.340460678317132, "MULTAQ": 3.908589244910284, "MYCAMINE": 4.9417342443794565, "NEVIRAPINE": 3.4900073648353533, "NEXAVAR": 5.969779730059007, "NORVIR": 17.575446734860776, "NOVONORM": 3.630345755487389, "NOXAFIL": 2.3434798526277407, "OCALIVA": 11.290404913775614, "OLYSIO": 14.887130439995582, "PANTOPRAZOLE": 1.439520132465009, "PAZOPANIB": 2.985917401333833, "PEGASYS": 1.6382787133750376, "PEGINTERFERON": 1.656490025419043, "PEGINTRON": 2.387202274608553, "PLAVIX": 2.095808299797725, "PRADAXA": 1.4011148704590368, "PRIVIGEN": 1.2908022293192365, "PROLIA": 3.6114092421598, "PROTELOS": 1.933949794226748, "RASILEZ": 1.8106266336692556, "REBETOL": 5.771683166589954, "REYATAZ": 56.45262549599393, "RIBAVIRIN": 3.4760911986690397, "SIMEPREVIR": 6.590644487737361, "SOLIRIS": 2.718728821578664, "SOVALDI": 7.378857502671108, "STIVARGA": 7.761999048342339, "SUBOXONE": 1.1572710701652045, "SUFENTANIL": 1.1099626353281569, "SUTENT": 2.2536639121021818, "TAMIFLU": 2.6097438912683906, "TASIGNA": 2.3496068836225987, "TEMODAL": 2.058926014751334, "TEMOZOLOMIDE": 2.7341669762548224, "TESTOSTERONE": 3.0896299929626605, "TIVICAY": 2.113807371817753, "TRACLEER": 2.7808980535423427, "TRACTOCILE": 8.924990547457472, "TRIUMEQ": 2.853275251708144, "TWINRIX": 2.9094060311870744, "VALDOXAN": 4.325328430327815, "VEMLIDY": 4.289553151657469, "VFEND": 1.484217322379614, "VICTOZA": 1.208296457773083, "VILDAGLIPTIN": 4.110742156128029, "VIRAMUNE": 14.291736992269046, "VORICONAZOLE": 1.3515371561301044, "VOTRIENT": 4.473662136858004, "XARELTO": 1.5392275861697249, "ZYPREXA": 1.022584914504468, "null": 2.3162581232411776}
\ No newline at end of file
+{"null": 3.3896906437938235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4623.json
index 59db88e4b0b..d83f8028cb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4623.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4623.json
@@ -1 +1 @@
-{"null": 1.35440634945964}
\ No newline at end of file
+{"IBUPROFEN": 49.44178507727904, "null": 0.6866926244750784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4624.json
index 7867e12375d..c440f5cc6e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4624.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4624.json
@@ -1 +1 @@
-{"ACLIDINIUM": 100.8431385813956, "AFINITOR": 1.2712272056956415, "ANORO": 5.676240934346821, "APTIVUS": 51.086931422449055, "ASPARAGINASE": 3.580166422718817, "AVANDIA": 1.3118546799109208, "BYDUREON": 4.363531748487131, "BYETTA": 30.374807251659902, "CASPOFUNGIN": 7.665421988098072, "CYTARABINE": 1.975099270609408, "EXJADE": 1.5266735949051826, "JANUMET": 2.251806406996531, "JANUVIA": 4.142499603626009, "KEYTRUDA": 1.3217157951548115, "MICARDIS": 3.599795558981817, "NEXAVAR": 6.9100771723361385, "PLAVIX": 1.233600781005384, "STIVARGA": 4.1565007985323765, "VFEND": 4.736084577014103, "VOTRIENT": 2.8791658437633068, "null": 2.55630729006296}
\ No newline at end of file
+{"null": 3.51233967253537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4625.json
index 94fd6455c6e..d8e828c93a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4625.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4625.json
@@ -1 +1 @@
-{"null": 1.8813434367449384}
\ No newline at end of file
+{"null": 2.3448760680099565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4626.json
index 6f4a552dc13..acfe7238125 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4626.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4626.json
@@ -1 +1 @@
-{"ABILIFY": 16.503846071316257, "BUPRENORPHINE": 21.893004660003403, "BUVIDAL": 200.11772087021816, "COMBIVIR": 7.267834109154724, "HUMALOG": 3.385428116203092, "INSULIN": 5.945557220737262, "KEPPRA": 3.526849387671743, "LANTUS": 2.950098941339058, "LEVEMIR": 41.368028329314974, "OPIOIDS": 117.36398677284554, "SUBOXONE": 80.40969868606038, "null": 1.1527241393001713}
\ No newline at end of file
+{"null": 2.386097647336676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4627.json
index ea3ae7f9f52..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4627.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4627.json
@@ -1 +1 @@
-{"AIMOVIG": 4.727877554123955, "BONVIVA": 25.82526582301634, "ELIQUIS": 1.2538511797456922, "IBRANCE": 4.293989566536973, "SUTENT": 4.672250491338108, "TELMISARTAN": 47.529180325284045, "XELJANZ": 1.862629635788613, "null": 1.0800268331484884}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4628.json
index 1c79eb061ce..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4628.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4628.json
@@ -1 +1 @@
-{"ANAKINRA": 9.31713815930538, "ATRIPLA": 16.89673923512782, "AZATHIOPRINE": 11.631778293340776, "ELIQUIS": 1.574645668096932, "FORSTEO": 3.038616370650522, "STRIBILD": 9.851149821781922, "SUBOXONE": 5.824291756266206, "TRUVADA": 12.156778381114195}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4629.json
index 2793bc905ca..2ceea27fa4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4629.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4629.json
@@ -1 +1 @@
-{"LEVODOPA": 617.832767470861, "null": 1.949924511750532}
\ No newline at end of file
+{"ATRIPLA": 3.934645453623324, "BONVIVA": 21.062285191614023, "CIMZIA": 0.7736807091424511, "CLOPIDOGREL": 1.3017858591253706, "COMIRNATY": 0.0627079625287858, "CYMBALTA": 1.3124680947674816, "DEXAMETHASONE": 1.641899229452118, "ELIQUIS": 2.569128843349466, "EVENITY": 109.3183785369566, "EVISTA": 8.434399314240418, "FORSTEO": 32.40047420047031, "HEPSERA": 48.62599775848373, "LIXIANA": 6.819362956609835, "OPSUMIT": 1.883453462430461, "TRUVADA": 2.394447525081536, "ZYPREXA": 1.2699556680249782, "null": 0.8793228055301464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/463.json
index 9c85b91da6d..b0c7925e37f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/463.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/463.json
@@ -1 +1 @@
-{"BEOVU": 451.4766247129453, "BROLUCIZUMAB": 657.2409346490258, "EYLEA": 218.07082240954225, "JETREA": 172.84936584715766, "null": 2.3000034235670075}
\ No newline at end of file
+{"PEGASYS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4630.json
index 624170e33ad..950d0c7d016 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4630.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4630.json
@@ -1 +1 @@
-{"null": 1.731601702195374}
\ No newline at end of file
+{"null": 0.6786973626991607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4631.json
index 6e265a90e53..d8187c433cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4631.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4631.json
@@ -1 +1 @@
-{"null": 1.0158469741257787}
\ No newline at end of file
+{"null": 4.740269002612894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4632.json
index 47e6bec42dc..831c4017c65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4632.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4632.json
@@ -1 +1 @@
-{"XELJANZ": 21.03533617693567}
\ No newline at end of file
+{"ABATACEPT": 1.417946507107644, "ADALIMUMAB": 1.4667291081739908, "AFINITOR": 0.5049651814944811, "APIDRA": 1.5067393544440333, "APIXABAN": 0.5546985172486619, "ARANESP": 0.8255633957840716, "ARAVA": 0.774983704989656, "ATRIPLA": 4.9124971686279215, "AVANDIA": 0.4703088403701178, "BONVIVA": 53.23844721348703, "BUPRENORPHINE": 0.951011956453718, "BYETTA": 0.8738851200765837, "CELECOXIB": 6.088412729507736, "CIMZIA": 0.5816806642494681, "CLOPIDOGREL": 0.3435226243462517, "COAPROVEL": 2.3209219092083795, "COMIRNATY": 0.0220068700320386, "COSENTYX": 0.3099364525068024, "CYMBALTA": 0.5398944681288244, "ELIQUIS": 2.067269680036953, "ENBREL": 5.1409521457003375, "ENTRESTO": 0.6233979351380379, "EVENITY": 55.55938056204546, "EVISTA": 18.86189667832693, "FASLODEX": 2.9607421653863133, "FORSTEO": 19.008392016031515, "FORXIGA": 0.9363477185111272, "GALVUS": 4.533766502952226, "HEPSERA": 5.182428961977306, "HIZENTRA": 1.1041752287740223, "HUMALOG": 2.5050691763079938, "HUMIRA": 0.6551413251065245, "IBRANCE": 2.662078761243323, "INLYTA": 1.1030410482313546, "JAKAVI": 1.5878702929419253, "JANUVIA": 0.5211935432435739, "JARDIANCE": 1.066840874106365, "KALETRA": 1.7087512525943127, "KEPPRA": 0.4198337200086943, "KEYTRUDA": 0.3168887086942615, "LANTUS": 2.066539056259168, "LEVEMIR": 0.8995668396222894, "LYRICA": 1.0023024915768717, "METHOTREXATE": 1.2922260616024903, "OPSUMIT": 1.2499935401703437, "PLAVIX": 0.4515219448239247, "PROLIA": 15.044543227503732, "REVATIO": 1.35510644982882, "RINVOQ": 1.124791257918034, "RITUXIMAB": 1.2446032648809733, "SIMPONI": 2.974252636318644, "SPIKEVAX": 0.0165323683035971, "SPINRAZA": 16.382098824429015, "STALEVO": 3.138210888517888, "STELARA": 0.3501716602452411, "STRIBILD": 4.241734620439612, "SUBOXONE": 1.298560958690293, "SUTENT": 1.2627799786623202, "TAGRISSO": 2.416476449857122, "TENOFOVIR": 9.745262188288708, "TERIPARATIDE": 16.10478800098519, "TRELEGY": 1.0396003863473748, "TRUVADA": 4.541301329245099, "VAXZEVRIA": 0.0114269247559146, "VFEND": 0.7363860181350202, "VIREAD": 5.714946019178719, "VOTRIENT": 0.541160886263451, "XELJANZ": 3.2992927743073546, "XOFIGO": 3.914800425238691, "XTANDI": 2.133065772637197, "ZOSTAVAX": 0.3112162880942461, "ZYPREXA": 0.4155751058673492, "null": 1.0139926522692784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4633.json
index f96a5b035e4..a99366b53c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4633.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4633.json
@@ -1 +1 @@
-{"ADALIMUMAB": 6.169708205474051, "ARAVA": 8.046287844131554, "CICLOSPORIN": 5.506056138313052, "COSENTYX": 59.35353231004366}
\ No newline at end of file
+{"SUBOXONE": 41.475511394527175, "null": 1.023860288544021}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4634.json
index a52efff9af2..cbcc63d475e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4634.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4634.json
@@ -1 +1 @@
-{"ANAKINRA": 185.2704447919268, "ARAVA": 4.161442644088457, "CIMZIA": 10.13906413396668, "ENBREL": 4.526261366401162, "FORSTEO": 6.511616270248247, "RINVOQ": 14.761714643336084, "SIMPONI": 15.044982719827551, "TRUVADA": 5.742276368623741}
\ No newline at end of file
+{"LEVOFLOXACIN": 281.7824941608508, "null": 0.6805743670107615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4635.json
index 4bf1b063dd3..bf15169ec40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4635.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4635.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.7109481791425936, "DULOXETINE": 9.870709952113874, "OPTIMARK": 465.8843764682989, "null": 1.3007413196990636}
\ No newline at end of file
+{"COMIRNATY": 0.6246112908127128, "SPIKEVAX": 12.5355319724461, "VAXZEVRIA": 2.2857593084146357}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4636.json
index 719f63d2b94..e6fd775b6af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4636.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4636.json
@@ -1 +1 @@
-{"ABATACEPT": 23.21624083253435, "ADALIMUMAB": 66.2930447971063, "ANAKINRA": 14.494195701865946, "ARAVA": 1.3409964435905757, "ENBREL": 10.2415698516852, "METHOTREXATE": 7.382546500159423, "XELJANZ": 4.925112803632064}
\ No newline at end of file
+{"AIMOVIG": 0.4844213818333406, "APIXABAN": 2.110568420283383, "CICLOSPORIN": 0.3039835429064614, "CLOPIDOGREL": 1.0602722781573448, "COMIRNATY": 2.851020645456908, "CYMBALTA": 0.1939297165494095, "ELIQUIS": 1.70957571702631, "ENOXAPARIN": 3.773735409118184, "FENTANYL": 2.530612735627697, "HUMIRA": 0.6855278746066907, "JARDIANCE": 0.3507745785885674, "KEYTRUDA": 0.657080803914093, "KYMRIAH": 5.915109796147887, "LEMTRADA": 1.70860320532902, "MEKINIST": 1.7252879316275005, "MODERNA": 1.5950653596439317, "OLANZAPINE": 0.6910995896813364, "OPDIVO": 1.3908158973957443, "RINVOQ": 1.6222492230443155, "SOLIRIS": 1.2401491485292049, "SPIKEVAX": 1.0570738103952797, "STIVARGA": 1.482666215303418, "TOZINAMERAN": 1.215795357522349, "VAXZEVRIA": 4.443021755136753, "XELJANZ": 0.295191200435078, "null": 0.2049949585835324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4637.json
index a13a33af26d..ac67d4e9801 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4637.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4637.json
@@ -1 +1 @@
-{"ABATACEPT": 5.583260710639072, "ADALIMUMAB": 5.663090527123753, "ARAVA": 5.753712258838939, "ATRIPLA": 1.1136401345070233, "BELIMUMAB": 69.43455530613893, "BENLYSTA": 3.1363259744576464, "CIMZIA": 1.422742181255428, "CLOPIDOGREL": 1.153763406138273, "CYMBALTA": 1.241008857271544, "ENOXAPARIN": 7.840903504745743, "EXFORGE": 2.020315567184119, "FORSTEO": 4.720388649758985, "GARDASIL": 2.0492379273751333, "HUMALOG": 1.1625808908768305, "KEPPRA": 1.2082213609549246, "LAMIVUDINE": 7.401791026363712, "LANTUS": 1.3840859331723876, "LEFLUNOMIDE": 9.49179086184493, "LEVETIRACETAM": 1.9125044350178164, "METHOTREXATE": 1.1580240250801814, "OMALIZUMAB": 4.119786123383254, "ORENCIA": 25.12274136452823, "RINVOQ": 3.87826984792312, "SIMPONI": 2.961737509164242, "SPINRAZA": 19.576110150056387, "SUBOXONE": 1.5449226494483956, "VIAGRA": 2.0967742615893536, "XELJANZ": 5.646604246621957, "XOLAIR": 1.4053360768506218, "XTANDI": 1.28246756878268, "XYREM": 5.122601361281031, "ZOSTAVAX": 1.2325710743262273, "null": 1.0849534574476178}
\ No newline at end of file
+{"COMIRNATY": 0.5224561037257761, "null": 2.0358689626663384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4638.json
index bcee7e7bc81..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4638.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4638.json
@@ -1 +1 @@
-{"ABATACEPT": 4.447180908591867, "ABILIFY": 5.74953079535982, "ADALIMUMAB": 2.681766553925517, "ANAKINRA": 5.571539098105633, "ARAVA": 1.5831891253238992, "BEXTRA": 30.172665544142905, "CIMZIA": 3.5393969472565843, "COSENTYX": 1.6844821525082805, "EMPAGLIFLOZIN": 9.595378390794128, "ENBREL": 3.564680666890032, "HUMIRA": 5.2913138708851495, "LEFLUNOMIDE": 11.517791896533558, "METHOTREXATE": 5.324050424101543, "ORENCIA": 35.654266509805666, "RINVOQ": 3.820260722652491, "ROACTEMRA": 2.02321047590045, "SIMPONI": 2.78675618818426, "STELARA": 1.111452564963359, "XELJANZ": 4.046440701763593, "ZOSTAVAX": 1.1144518111123791, "null": 1.801576732893981}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4639.json
index eb2178189d4..4aaa098c249 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4639.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4639.json
@@ -1 +1 @@
-{"GARDASIL": 11.915493764137414, "null": 2.330669416153329}
\ No newline at end of file
+{"null": 1.1886398168110262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/464.json
index d3c2bfe2526..34ae4836625 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/464.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/464.json
@@ -1 +1 @@
-{"null": 6.249107449882757}
\ No newline at end of file
+{"COMBIVIR": 21.752127181864463, "HARVONI": 16.875268978623797, "NEXAVAR": 262.19548775766816, "PEGASYS": 10.339133414728591, "SORAFENIB": 117.58745308698218, "STIVARGA": 8.002770564380778, "null": 0.1819202089910451}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4640.json
index a3a91823e71..80d5e99ec00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4640.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4640.json
@@ -1 +1 @@
-{"ABATACEPT": 2.647338466343225, "ADALIMUMAB": 1.7715436489204113, "ADVATE": 24.11801714283509, "AFINITOR": 1.401916175082264, "ANAKINRA": 10.07924266986508, "ARAVA": 4.748705729083529, "ATRIPLA": 1.9416518894832788, "AUBAGIO": 2.296500462126027, "BUPRENORPHINE": 1.240726346535575, "BYDUREON": 1.7003897258436769, "BYETTA": 1.0280150746889354, "CIMZIA": 2.687809998281132, "COSENTYX": 1.2114982618860644, "ELIQUIS": 2.045641108151069, "ENBREL": 19.67202122347509, "ENTRESTO": 1.1384400656272244, "FAMPYRA": 2.018341606893371, "FASLODEX": 1.6081432387783043, "FIRDAPSE": 3.9161525349876736, "FORSTEO": 2.053027434450842, "HEMLIBRA": 13.858352433988214, "HUMALOG": 3.1752238367787284, "HUMIRA": 6.441841189722935, "IBRANCE": 2.2942220190668263, "INSULIN": 1.1718860150167107, "KEPPRA": 1.0245370549791066, "KOVALTRY": 67.81377526866912, "LANTUS": 2.403380703548882, "LYRICA": 2.096177884898779, "METHOTREXATE": 1.422310642948137, "NUCALA": 1.396572707963617, "OMALIZUMAB": 1.7857141259780809, "PAIN": 330.36144888742234, "REVATIO": 1.999681214815903, "SIMPONI": 1.9135428292678824, "STRIBILD": 1.2774412833323403, "SUBOXONE": 4.029814938029937, "TOVIAZ": 2.7403460407402047, "TRUVADA": 1.0937600119689506, "VIAGRA": 1.9863827331578048, "VICTOZA": 1.3282065309306412, "XELJANZ": 6.666711606733356, "XOLAIR": 1.0435106422615117, "XYREM": 4.204518378548572, "ZOSTAVAX": 3.4829098160259115}
\ No newline at end of file
+{"MIDAZOLAM": 231.0603295074856, "null": 0.8825139090080125}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4641.json
index d18e0828849..5e1dacbb753 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4641.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4641.json
@@ -1 +1 @@
-{"OPTIMARK": 14.767543283681883, "null": 1.2488254690536962}
\ No newline at end of file
+{"null": 1.574165341041632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4642.json
index e57c553c61e..c25aa699f8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4642.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4642.json
@@ -1 +1 @@
-{"ADALIMUMAB": 4.350782953810553, "ARAVA": 5.151766884011396, "ENBREL": 30.58901823370553, "null": 1.8959801352126116}
\ No newline at end of file
+{"CICLOSPORIN": 34.24860108900526, "COMIRNATY": 0.5649183524447262, "CYMBALTA": 5.000017891119244, "GARDASIL": 6.6079039566281255, "KEPPRA": 5.975115561111926, "null": 0.9446375209246282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4643.json
index 8fe2fd83718..431516cee52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4643.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4643.json
@@ -1 +1 @@
-{"ARAVA": 3.154680827114403, "CIMZIA": 2.5450388060309463, "COVID19": 1.3602296038216728, "ENBREL": 3.242084077554121, "GARDASIL": 4.4892970446945055, "OPTIMARK": 16.027510860816882, "RINVOQ": 11.360775186187848, "SIMPONI": 3.547812834321786, "TOZINAMERAN": 2.0736027756802224, "XELJANZ": 4.297733580675227}
\ No newline at end of file
+{"TENOFOVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4644.json
index 44a0065fcc5..71c8d73bc52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4644.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4644.json
@@ -1 +1 @@
-{"BIKTARVY": 9.535371885678456, "CLOPIDOGREL": 2.1055990792331785, "COSENTYX": 3.201232425602569, "CYMBALTA": 21.74015705043135, "DULOXETINE": 14.122940453543968, "ENBREL": 3.36417806254582, "GARDASIL": 3.4018527997399164, "HUMIRA": 14.273851830983068, "LEVOFLOXACIN": 4.902634522660343, "STELARA": 2.070339173151736, "TOZINAMERAN": 2.23429294556314, "XELJANZ": 3.4604514031083955}
\ No newline at end of file
+{"COMIRNATY": 0.1618620545967833, "ZOSTAVAX": 10.297440614012462, "null": 3.079681721479681}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4645.json
index af5100936fd..26dbdc984fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4645.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4645.json
@@ -1 +1 @@
-{"ABATACEPT": 16.99471452308404, "ADALIMUMAB": 12.644413154790112, "ANAKINRA": 2.9220206063504315, "ARAVA": 3.7405211176097497, "CELECOXIB": 2.138890373831185, "CIMZIA": 1.7728966087203748, "CLINDAMYCIN": 43.28735853395841, "CONTRAST": 78.02612673435942, "COSENTYX": 6.383593828039476, "CYMBALTA": 1.194228797445982, "ENBREL": 7.721827725946437, "HUMIRA": 8.955495527909804, "LEFLUNOMIDE": 4.962151690682721, "MELATONIN": 4.003513871482803, "METHOTREXATE": 1.6504130208426673, "OPTIMARK": 72.14303258211316, "RINVOQ": 1.6156022246156865, "RITUXIMAB": 1.517859845086331, "SHINGRIX": 1.0617427453688115, "TOZINAMERAN": 3.819706773869732, "XELJANZ": 3.316824384480165, "ZOSTAVAX": 1.4344654725728962}
\ No newline at end of file
+{"COMIRNATY": 0.4645590539668642, "null": 2.0577197337142827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4646.json
index 4315f27e24b..c1bbb4b698c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4646.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4646.json
@@ -1 +1 @@
-{"ARAVA": 3.845334368217507, "HUMIRA": 60.52690974700181, "LEFLUNOMIDE": 153.82420829794847}
\ No newline at end of file
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4647.json
index 0fe10dc2b12..2b96d5ac351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4647.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4647.json
@@ -1 +1 @@
-{"ABATACEPT": 3.577990529636573, "ABRAXANE": 8.050645948755175, "ADALIMUMAB": 3.236302820919654, "AIMOVIG": 1.5318998154131347, "AMINOSALICYLIC": 1.7413352300989515, "ARAVA": 6.916842347449433, "AZATHIOPRINE": 2.1005775604798003, "BOTULINUM": 2.7210559583580967, "CERTOLIZUMAB": 16.358608296790425, "CHAMPIX": 1.126148970447317, "CIMZIA": 2.823734743517155, "CONTRAST": 27.12880409702899, "COSENTYX": 4.589818025062403, "COVID19": 1.1693289095203685, "EFAVIRENZ": 2.839482201355063, "ENBREL": 7.448883067901711, "ENTYVIO": 1.9548012181754528, "GARDASIL": 1.2282030136723632, "HUMIRA": 6.534394169315148, "IBRANCE": 1.3451047349446033, "ICLUSIG": 1.1776484036634671, "LEFLUNOMIDE": 2.841665804021809, "LEVOFLOXACIN": 1.1171591983908962, "METHOTREXATE": 2.5267073441297434, "OPTIMARK": 31.912287800336237, "RINVOQ": 1.2643813459658315, "RITUXIMAB": 1.2271362560440944, "SHINGRIX": 1.0897525883128294, "SIMPONI": 1.340821423097998, "TOZINAMERAN": 2.0010797100397326, "XELJANZ": 2.5559959006934543}
\ No newline at end of file
+{"null": 1.4001987331027643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4648.json
index 65998230a5a..d1cbdc36a87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4648.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4648.json
@@ -1 +1 @@
-{"ARAVA": 11.199576096141415, "SIMPONI": 22.57062903151303}
\ No newline at end of file
+{"ABATACEPT": 13.867897090605986, "ABILIFY": 0.5068942181129458, "ACLASTA": 11.566126105421327, "ADALIMUMAB": 19.820423658705856, "AIMOVIG": 0.9140779718987864, "APIXABAN": 28.533907040667657, "APREMILAST": 12.549137230118596, "APREPITANT": 1.6472001611946134, "ARAVA": 4.219781727824279, "AUBAGIO": 0.2688295687206388, "AVONEX": 5.885271341552556, "BENLYSTA": 2.4156415864492544, "BRINTELLIX": 0.5953419605138237, "BUDESONIDE": 0.2255306640578083, "BYDUREON": 1.4121959799227457, "CANNABIDIOL": 8.89091662842922, "CELECOXIB": 5.942398000589662, "CHAMPIX": 0.2929963804243272, "CIMZIA": 2.296382009721766, "CLOPIDOGREL": 4.016626254302802, "COMIRNATY": 0.4823783412506749, "COSENTYX": 2.4847293825022576, "CYMBALTA": 3.3446197227359904, "DULOXETINE": 1.925137191377456, "ELIQUIS": 1.1176547992741457, "ENBREL": 5.43304050658926, "ENTYVIO": 0.7676277872470665, "ERENUMAB": 4.311736226389039, "ESOMEPRAZOLE": 2.507965038436624, "EXFORGE": 0.5529589245767572, "FENTANYL": 0.3605456001899116, "FORSTEO": 0.5319609148687127, "GARDASIL": 3.5640499589806574, "HUMALOG": 0.9618300766145242, "HUMIRA": 5.40110331648273, "HYDROCORTISONE": 1.0861288792652095, "IBRANCE": 0.16524842835573, "IBUPROFEN": 0.9556914194435668, "JANUMET": 0.6735132624900934, "JANUVIA": 0.3250157381343111, "KEPPRA": 0.1741418164199753, "LANTUS": 0.7016455720216542, "LEFLUNOMIDE": 2.7804507521602626, "LEVOFLOXACIN": 0.5359387680834744, "LYRICA": 6.98306858402557, "METHOTREXATE": 5.406653963898446, "MYCOPHENOLATE": 2.1538809714135656, "OMALIZUMAB": 1.341131150242053, "PEGASYS": 0.6646838634372723, "PEGINTRON": 0.3552409941172128, "RITUXIMAB": 2.234812505911918, "SAXENDA": 0.5283950266408031, "SIMPONI": 1.6320051308496522, "SPIKEVAX": 0.3246563079483561, "STELARA": 0.3210577943796454, "SUBOXONE": 0.6399602018646533, "TOZINAMERAN": 0.7955865096126107, "VAXZEVRIA": 0.4324023881229057, "XELJANZ": 2.3882262325419377, "XOLAIR": 0.853938974343446, "XYREM": 6.786034529679121, "ZOSTAVAX": 2.291531178921954, "null": 0.3927649410552273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4649.json
index a9b6814ac42..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4649.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4649.json
@@ -1 +1 @@
-{"ABACAVIR": 12.71982779552135, "ABATACEPT": 10.146508111296583, "ACETAMINOPHEN": 11.752481310346198, "ACLASTA": 2.5442527299246827, "ADALIMUMAB": 5.042472328597467, "ADVATE": 3.1137597639486088, "AMBRISENTAN": 1.2445423335660797, "ANAKINRA": 13.605380101333427, "APREMILAST": 5.527664314302268, "APREPITANT": 1.328474794032794, "ARAVA": 14.254563836023484, "AZATHIOPRINE": 2.194248321956379, "BENLYSTA": 1.6442573993558138, "BETMIGA": 2.239649734535078, "BOSENTAN": 1.3218187011318892, "CELECOXIB": 1.1362834125102237, "CHLORHEXIDINE": 17.78470688299086, "CIMZIA": 10.015853476221784, "COSENTYX": 4.798686794716206, "DULOXETINE": 1.084399750802674, "DUPIXENT": 1.132582413324447, "EMPAGLIFLOZIN": 1.3275891511985507, "ENBREL": 11.469738339878925, "EPOETIN": 1.6218397743667448, "ERELZI": 9.928168066860168, "ETANERCEPT": 6.734660466452948, "EXFORGE": 3.615368351977585, "FORSTEO": 1.0569544675522595, "HEMLIBRA": 2.0475177380630503, "HIZENTRA": 1.099540592936511, "HUMIRA": 4.133262471655464, "IDACIO": 2.460918729537112, "INFLECTRA": 2.018960404184452, "KEVZARA": 6.192097503644567, "KOVALTRY": 4.475144717503885, "LEFLUNOMIDE": 10.527028446441618, "LUPKYNIS": 2.491234741061107, "METHOTREXATE": 4.705871396889209, "OPTIMARK": 1.6020599617372977, "ORENCIA": 2.9086239638211517, "PANTOPRAZOLE": 1.0737441609882878, "RINVOQ": 2.332162037565584, "RITUXIMAB": 2.604745402270192, "ROACTEMRA": 1.4808632184681592, "SIMPONI": 2.242319374163817, "TEDUGLUTIDE": 4.895485853124828, "TOFACITINIB": 4.312288669455672, "TWINRIX": 1.2595982473195066, "VORTIOXETINE": 3.38548286213186, "XELJANZ": 3.287765766670077, "XOLAIR": 1.1921913207154842, "XTANDI": 1.0463544983998383, "ZELBORAF": 1.1359689183570083}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/465.json
index 7a90e0580ef..5b40916e4ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/465.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/465.json
@@ -1 +1 @@
-{"BUPIVACAINE": 886.5884144463513, "FENTANYL": 103.42466271312291}
\ No newline at end of file
+{"OMALIZUMAB": 120.36878387311698, "null": 0.7371811038850543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4650.json
index e1612282283..11f31ea0ebb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4650.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4650.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.0281398186509296, "CIMZIA": 2.2675807696834, "COMIRNATY": 1.211429758511022, "COVID19": 1.0200461608154938, "ENBREL": 6.124928793805195, "TOZINAMERAN": 1.0021486497690946, "null": 1.002404486567506}
\ No newline at end of file
+{"null": 0.8204645188478649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4651.json
index 5e43ed4f8c5..2626bc15737 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4651.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4651.json
@@ -1 +1 @@
-{"BUDESONIDE": 5.5476410451567295, "CHAMPIX": 4.025293448344396, "FENTANYL": 4.735597189916646, "MELATONIN": 46.47530925376212, "OLANZAPINE": 7.769870232645914, "PEGASYS": 1.752948477604729, "null": 3.4935845418473277}
\ No newline at end of file
+{"VOTRIENT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4652.json
index 5cb2e14a036..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4652.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4652.json
@@ -1 +1 @@
-{"AVANDIA": 9.058979089733969, "CLOPIDOGREL": 10.43206311564773, "null": 1.5832566650608149}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4653.json
index edd1110a57b..79de0940ee9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4653.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4653.json
@@ -1 +1 @@
-{"AFINITOR": 3.082204146471866, "AVASTIN": 9.749576248004312, "COVID19": 1.0039773306802855, "ELIQUIS": 1.77362313294872, "GONALF": 71.13364711043621, "NOVOSEVEN": 71.44507794814716, "ONCASPAR": 38.610380459476936, "VAXZEVRIA": 2.3607087248814063}
\ No newline at end of file
+{"APTIVUS": 124.22201749932825, "ARAVA": 0.2755807163255433, "ARIPIPRAZOLE": 4.041501462766648, "CARFILZOMIB": 19.57324064135173, "CICLOSPORIN": 1.5687044962427952, "COMIRNATY": 0.0342180937014066, "CONTRAST": 70.83132362950919, "ESBRIET": 6.722772049541165, "ETANERCEPT": 46.05946083510741, "EXJADE": 2.731191176654721, "EXVIERA": 27.12601783360264, "JAKAVI": 6.9906185844532684, "NPLATE": 8.887544667574392, "OPTIMARK": 289.6170777983042, "PEGASYS": 2.5639962661187194, "VAXZEVRIA": 0.0414538937259508, "null": 0.8191898155009931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4654.json
index 4359f90e911..19e684bc3c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4654.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4654.json
@@ -1 +1 @@
-{"ABATACEPT": 12.696302798484156, "ADALIMUMAB": 7.35401750983562, "ANAKINRA": 70.2697565729198, "ARIPIPRAZOLE": 8.318444244867306, "CICLOSPORIN": 5.812208673927205, "CIMZIA": 11.807830585579676, "COSENTYX": 5.946446007780346, "ENBREL": 4.09626974103659, "GARDASIL": 9.383357027318214, "HUMIRA": 10.59574221614061, "LEFLUNOMIDE": 17.825178915798027, "MMRVAXPRO": 3.620966937599512, "ROACTEMRA": 13.54834243078919, "SIMPONI": 5.119132332524507}
\ No newline at end of file
+{"HEPSERA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4655.json
index 81b0c605662..db7aae691de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4655.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4655.json
@@ -1 +1 @@
-{"GARDASIL": 64.7540181829206}
\ No newline at end of file
+{"null": 1.358446126336236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4656.json
index 83a930b0827..a29933b7991 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4656.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4656.json
@@ -1 +1 @@
-{"AFINITOR": 49.38753817057257, "AVASTIN": 12.268590074793543, "COSENTYX": 6.994506588095212, "FASLODEX": 11.429160290591463, "KEYTRUDA": 25.46344956280277, "OFEV": 15.814963824351024}
\ No newline at end of file
+{"null": 1.7513232568098986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4657.json
index dde3221b302..2131713a245 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4657.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4657.json
@@ -1 +1 @@
-{"ABACAVIR": 9.935784191756234, "ATAZANAVIR": 52.28693377172978, "BASILIXIMAB": 31.38938057871821, "BIKTARVY": 30.559655366828103, "BUSULFAN": 14.889126175579989, "CARMUSTINE": 40.38646349054193, "CELLCEPT": 17.05872921082625, "CICLOSPORIN": 44.73917367212656, "COMBIVIR": 26.95667750797016, "DESCOVY": 47.905623362700105, "EFAVIRENZ": 107.17435288554265, "EMTRICITABINE": 25.14681877757972, "JAKAVI": 7.694048429168653, "KALETRA": 16.64967424057314, "LAMIVUDINE": 22.47138384422397, "METHOTREXATE": 2.535430934241771, "MYCOPHENOLATE": 29.32600102404875, "TIVICAY": 36.84762850203537, "TRUVADA": 1.6333543785938271}
\ No newline at end of file
+{"ATRIPLA": 27.272547950066087, "FORSTEO": 8.959882516500628, "LANTUS": 1.3023898611940772, "STRIBILD": 11.484953535141832, "SUBOXONE": 5.897810484915893, "TRUVADA": 15.340182869365684, "XELJANZ": 2.2613397808861437, "null": 0.4872204363785478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4658.json
index 20ad78e4089..1933c4a1896 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4658.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4658.json
@@ -1 +1 @@
-{"BEXSERO": 93.7734614942848, "INFANRIX": 124.2521410591262, "NIMENRIX": 22.032591417892377, "PREVENAR": 157.69709419386817, "ROTATEQ": 258.4659671772212, "null": 1.5390519165959111}
\ No newline at end of file
+{"BYETTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4659.json
index 51b20efa371..207ba3ddc7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4659.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4659.json
@@ -1 +1 @@
-{"null": 1.532751407690044}
\ No newline at end of file
+{"null": 4.40329870614908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/466.json
index d37e07b6196..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/466.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/466.json
@@ -1 +1 @@
-{"null": 1.89410968155978}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4660.json
index 8e3b9943197..b0c7925e37f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4660.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4660.json
@@ -1 +1 @@
-{"BEOVU": 1156.887711329971, "BROLUCIZUMAB": 427.41863587669104, "EYLEA": 115.21060924115991, "null": 1.9503788466013152}
\ No newline at end of file
+{"PEGASYS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4661.json
index c551931eeaf..ce28ccca0e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4661.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4661.json
@@ -1 +1 @@
-{"ABATACEPT": 3.641507070727722, "ADALIMUMAB": 1.27168806512026, "ARAVA": 2.0890813479578694, "BUSULFAN": 5.713810577548849, "CICLOSPORIN": 2.231529110007328, "CYTARABINE": 4.042691824278513, "EYLEA": 11.272315394999668, "KEYTRUDA": 2.243657324371274, "NEVANAC": 40.83127661989203, "PEGASYS": 1.252001821031045, "ROACTEMRA": 4.899352643818668, "SHINGRIX": 2.306277065812683, "TAGRISSO": 19.58168248049645, "TOBRAMYCIN": 51.800995212431694, "ZOSTAVAX": 4.112810337089968, "null": 1.359078185728576}
\ No newline at end of file
+{"null": 5.752821276950427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4662.json
index d0d9bc637f7..f24ade45f71 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4662.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4662.json
@@ -1 +1 @@
-{"null": 1.0692175350699895}
\ No newline at end of file
+{"ADALIMUMAB": 1.7433013366068333, "ANAKINRA": 8.65036164497117, "ARAVA": 5.1734118156314, "AUBAGIO": 2.5222261475367898, "CIMZIA": 4.224482099589967, "COMIRNATY": 0.9587803012994092, "CYMBALTA": 3.0598883675315918, "ENBREL": 4.365088791203441, "FAMPYRA": 10.186044891174722, "HUMALOG": 2.641471997360679, "IBUPROFEN": 13.427173322029796, "LANTUS": 1.1584252916094129, "METHOTREXATE": 2.5997995003540164, "ORENCIA": 59.34257728786208, "SPIKEVAX": 0.8698394587779533, "TOZINAMERAN": 0.5853837616159716, "VAXZEVRIA": 0.3688709229366592, "null": 0.7954529091076388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4663.json
index b3080dd132e..f174b458312 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4663.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4663.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 34.7178714916898, "VORICONAZOLE": 197.4420336351838}
\ No newline at end of file
+{"null": 0.9966940138996306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4664.json
index 5eaa7eda813..e15d2aea7d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4664.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4664.json
@@ -1 +1 @@
-{"NEXAVAR": 25.238659201396885, "VEMURAFENIB": 997.8325576393898, "ZELBORAF": 699.656364211994}
\ No newline at end of file
+{"ABATACEPT": 4.598575359437049, "ADALIMUMAB": 24.87640129551497, "ANAKINRA": 5.790085745544645, "APREMILAST": 24.512138915914203, "ARAVA": 11.551486270046196, "CIMZIA": 0.886310661866032, "COMIRNATY": 0.0886211717298012, "COSENTYX": 2.863294578804944, "ENBREL": 14.070033069174912, "HUMIRA": 3.734259816307248, "METHOTREXATE": 2.203994698567095, "RITUXIMAB": 8.281403143467042, "SIMPONI": 2.0534771549350617, "VAXZEVRIA": 0.0554798130539707, "XELJANZ": 10.229696425929305, "null": 0.5793873906353617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4665.json
index 9196bb6adae..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4665.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4665.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 29.43380923749087}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4666.json
index d21d25573f9..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4666.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4666.json
@@ -1 +1 @@
-{"null": 3.018048574023795}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4667.json
index 3903c0b349a..14e35683fe6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4667.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4667.json
@@ -1 +1 @@
-{"BELANTAMAB": 6664.325700344432, "BLENREP": 9172.99842238755, "COMBIVIR": 32.03417284330178, "DEXAMETHASONE": 9.379329769038405, "FLORAJEN": 8587.701475032678, "LEVOFLOXACIN": 15.475580989096027, "null": 1.7051019752203735}
\ No newline at end of file
+{"ABILIFY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4668.json
index 6da6e667bec..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4668.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4668.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4669.json
index dd86ced9818..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4669.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4669.json
@@ -1 +1 @@
-{"VEMURAFENIB": 695.27951974193, "ZELBORAF": 657.729500189497}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/467.json
index 04232d6e93e..0d4f33f246b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/467.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/467.json
@@ -1 +1 @@
-{"PRIVIGEN": 411.1213401477086, "null": 1.605070692234245}
\ No newline at end of file
+{"null": 1.4293166421256611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4670.json
index a76a7eec579..8ddd36c247b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4670.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4670.json
@@ -1 +1 @@
-{"null": 2.5907254632306738}
\ No newline at end of file
+{"KAFTRIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4671.json
index 03b778baaf1..d22cc732a5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4671.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4671.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"ADALIMUMAB": 0.3471247855795609, "ARAVA": 0.2545366747531643, "AVASTIN": 14.681941022262109, "BEVACIZUMAB": 4.161364474694855, "CELLCEPT": 2.1194272650408985, "CIMZIA": 13.355300283373024, "COSENTYX": 2.4087457199940085, "ENTYVIO": 21.32662641913339, "HUMALOG": 1.089228274716534, "HUMIRA": 16.56549956014746, "KEYTRUDA": 4.291762525529296, "LENVIMA": 31.70052200738032, "MEKINIST": 3.3919802748936925, "NEXAVAR": 3.379818527178277, "REMICADE": 12.746539596079325, "SIMPONI": 3.343145974005516, "STELARA": 25.698917944548363, "SUTENT": 3.503006845329977, "VOTRIENT": 3.5527752285482546, "XELJANZ": 2.5373645999125016, "null": 0.5241382872663426}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4672.json
index 2fde2bdfcb3..75747011ac6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4672.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4672.json
@@ -1 +1 @@
-{"ABASAGLAR": 6.167752790524029, "ACTRAPID": 10.444151458625472, "ALPELISIB": 12.542344745093494, "APIDRA": 11.672285212230252, "ASPARAGINASE": 1.352912344614831, "CANAGLIFLOZIN": 34.979973407299255, "DAPAGLIFLOZIN": 10.097327844507474, "DULAGLUTIDE": 19.77850962049849, "EMPAGLIFLOZIN": 63.66953893745229, "FIASP": 5.855454631323342, "FORXIGA": 104.63732628172863, "GLIBENCLAMIDE": 6.751282271018541, "HUMALOG": 13.481705582495389, "INSULIN": 10.827389162752286, "INSUMAN": 14.836894349817989, "INVOKANA": 49.04761660825751, "JANUVIA": 2.084633540938085, "JARDIANCE": 208.16694170313176, "KEYTRUDA": 1.4450210383314268, "LANTUS": 9.20026625241413, "LEVEMIR": 6.9490218930578544, "NOVORAPID": 8.495371101314843, "OLANZAPINE": 1.9644436608080311, "PIQRAY": 20.65949515863162, "SPINRAZA": 1.996293559041054, "TOUJEO": 3.240557177342316, "TRESIBA": 5.480055809648136, "TRULICITY": 3.762546353834728, "VICTOZA": 1.228452146020086, "ZYPREXA": 5.664235703338711}
\ No newline at end of file
+{"HUMIRA": 62.66501918978206, "STELARA": 24.844094562564337, "null": 0.4423718904223737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4673.json
index 48df1b7e829..eff8bd1aaae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4673.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4673.json
@@ -1 +1 @@
-{"APIDRA": 9.11514108200945, "DULOXETINE": 14.911697593254065, "EMPAGLIFLOZIN": 32.904785171522995, "FORXIGA": 97.40088812751004, "HUMALOG": 5.066176920903752, "JARDIANCE": 68.26688936820682, "LANTUS": 7.680987524592225, "OLANZAPINE": 4.960717835746749, "ZYPREXA": 6.1369292381943765}
\ No newline at end of file
+{"SUTENT": 9.323279106639555, "null": 0.2614686748157742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4674.json
index 8b09ff94c3c..e75c5813025 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4674.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4674.json
@@ -1 +1 @@
-{"APIDRA": 10.538052985742596, "EMPAGLIFLOZIN": 35.91606200639334, "FORXIGA": 70.77371146235515, "HUMALOG": 10.904758441045582, "INSULIN": 7.870263036008226, "JARDIANCE": 77.69950993819063, "LANTUS": 10.197001980418134, "NOVORAPID": 15.509255853264104, "ZYPREXA": 3.2793548960857444}
\ No newline at end of file
+{"INSULATARD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4675.json
index 94deca11aa8..151dfa56e93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4675.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4675.json
@@ -1 +1 @@
-{"CYMBALTA": 27.791510508102203}
\ No newline at end of file
+{"AIMOVIG": 3.779792294606543, "COMIRNATY": 0.0980326496069849, "IBUPROFEN": 3.0815867775439307, "KEPPRA": 1.9488354191601032, "LEVOFLOXACIN": 14.21845248033594, "PANTOPRAZOLE": 6.129252355458736, "SPIKEVAX": 0.0834970549007641, "VAXZEVRIA": 0.0811586785816893, "null": 5.577252029670122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4676.json
index 5015a9e2967..8b2df5c1e54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4676.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4676.json
@@ -1 +1 @@
-{"ASPARAGINASE": 287.64491534754814}
\ No newline at end of file
+{"ABILIFY": 5.121167666456209, "ADALIMUMAB": 0.1348883293773719, "AFINITOR": 1.5822263748659278, "ATRIPLA": 0.1632171825718227, "BYDUREON": 1.0839472495242268, "BYETTA": 2.623543066663012, "CICLOSPORIN": 0.4235695453286114, "CLOPIDOGREL": 0.6285113130649063, "COMIRNATY": 0.9504553217759572, "CRIXIVAN": 36.12835741627367, "CYMBALTA": 0.4930561974710652, "CYTARABINE": 1.157910030130079, "ELIQUIS": 0.4113495777750516, "ENOXAPARIN": 7.221311966094597, "EXJADE": 2.78815378709898, "FLEBOGAMMA": 6.981764310056512, "FORSTEO": 1.4033359042954778, "FORXIGA": 4.03191970045832, "GARDASIL": 1.7357779328862912, "HIZENTRA": 1.8230196837967445, "INSULIN": 13.795186314444358, "JANUMET": 1.4766792046021444, "JARDIANCE": 1.5407228813610456, "KEYTRUDA": 0.570992506898805, "MEPOLIZUMAB": 2.9213885661169456, "NEXAVAR": 0.8390921817055113, "NUCALA": 1.9997915307525007, "OPSUMIT": 1.4266140347950638, "PEGASYS": 0.8229328403039927, "PLAVIX": 0.8721234499405167, "PRIVIGEN": 3.1266282212611496, "SAXENDA": 1.584035190522198, "SHINGRIX": 1.3785368682252082, "SOLIRIS": 1.2006573462961476, "SPIKEVAX": 1.003000401293353, "SUTENT": 1.819021230741267, "TOZINAMERAN": 0.795739856446791, "VAXZEVRIA": 0.6969474615765144, "VOTRIENT": 1.630281278993047, "XELJANZ": 1.2002070163958178, "XOLAIR": 0.9859648521819292, "XTANDI": 1.0522675657383844, "ZOSTAVAX": 1.4646697691905826, "null": 0.8461814392840591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4677.json
index 2347f192d45..36a2f34e9c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4677.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4677.json
@@ -1 +1 @@
-{"ATRIPLA": 1.261283207280578, "TRUVADA": 2.1221588922214827, "null": 1.5248089309939237}
\ No newline at end of file
+{"null": 4.799161565403609}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4678.json
index 83d5314f4a7..917444bfddf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4678.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4678.json
@@ -1 +1 @@
-{"ATRIPLA": 1.3526449591975631, "BASILIXIMAB": 60.67202096809904, "CELLCEPT": 4.338562430805784, "CICLOSPORIN": 32.48889372031274, "GANCICLOVIR": 28.75917029524525, "MYCOPHENOLATE": 27.65951176374417, "PEMETREXED": 29.308097536992346, "SOLIRIS": 11.370703177887169, "TRUVADA": 3.869070493460961, "null": 1.1801061807439333}
\ No newline at end of file
+{"CHAMPIX": 12.205967416860345, "null": 2.518016064086473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4679.json
index a143e275b94..06e66f93525 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4679.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4679.json
@@ -1 +1 @@
-{"ABATACEPT": 1.39837067948114, "APIDRA": 2.0473225956662087, "ARANESP": 1.3382379680659222, "ARAVA": 3.107948667693437, "ATRIPLA": 1.5991807409607457, "AUBAGIO": 3.4070374682710747, "AVAMYS": 1.9939284096392385, "AZATHIOPRINE": 1.2640921344225569, "BELIMUMAB": 49.62409140117257, "BENLYSTA": 10.250514397730178, "BYETTA": 1.442982010297177, "CELLCEPT": 1.8091294944543903, "CIMZIA": 2.5763847489257863, "COSENTYX": 2.669989993338089, "ELIQUIS": 1.2448890152032226, "ENBREL": 1.219855963336005, "ENTYVIO": 1.020921199711882, "ESBRIET": 1.8713945480924044, "EXFORGE": 1.4276544258305028, "EXJADE": 1.73616757959162, "FAMPYRA": 2.202146993378619, "FORSTEO": 1.07950070710634, "FORXIGA": 1.15511127151754, "HIZENTRA": 10.667244022158858, "HUMALOG": 1.6238258921305797, "IBRANCE": 3.701058777999565, "INVOKANA": 6.30676188283176, "JANUMET": 1.0342677378408724, "JARDIANCE": 2.6110560738932667, "KALETRA": 5.590742591530742, "LANTUS": 2.634550357109484, "LEVEMIR": 1.7630752004583443, "MEKINIST": 1.285937758272875, "NUCALA": 10.887913238337584, "OMALIZUMAB": 1.7411769343754404, "OPSUMIT": 1.7574551537711929, "PRIVIGEN": 1.97724310081412, "RINVOQ": 1.1591558103207409, "ROACTEMRA": 1.4707709426975013, "RUCONEST": 16.055461176545894, "SAXENDA": 1.2190924270707462, "SIMPONI": 5.884316091920942, "SOLIRIS": 1.4355547002319091, "SPRYCEL": 1.416605391744764, "STELARA": 2.7069662444856606, "STRIBILD": 1.245567640251018, "SUBOXONE": 1.6510397062028013, "SUTENT": 1.1066766807387858, "SYNAGIS": 1.8921586320099624, "TOVIAZ": 3.9097138864339738, "TRACLEER": 1.1568083253256436, "TRELEGY": 1.042839527857334, "TREMFYA": 4.622606967974088, "TRULICITY": 1.084294269961966, "TRUVADA": 1.1416464371049295, "VICTOZA": 1.8181024228102376, "VOTRIENT": 1.060506169492692, "XELJANZ": 9.231758312758531, "XOLAIR": 1.557163990716539, "XTANDI": 2.464779679548623}
\ No newline at end of file
+{"ABILIFY": 5.288483529394699, "CHAMPIX": 14.006863644612585, "COMIRNATY": 0.2174895622704219, "CYMBALTA": 3.2245468868452765, "LATUDA": 17.755906768969258, "OLANZAPINE": 4.068189504224402, "SPIKEVAX": 0.1527140279651353, "TOZINAMERAN": 0.5316571846273355, "ZYPREXA": 8.35110303422757, "null": 1.8215118147330065}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/468.json
index f740c42fd0b..20098bd1310 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/468.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/468.json
@@ -1 +1 @@
-{"NOVOSEVEN": 4404.315166762161}
\ No newline at end of file
+{"OMALIZUMAB": 120.36878387311698, "null": 0.4504694085973649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4680.json
index 3dc8caafa67..fa1b2937ffc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4680.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4680.json
@@ -1 +1 @@
-{"IBUPROFEN": 25.27663583011697, "KALETRA": 27.203422015822767, "null": 3.684371222587131}
\ No newline at end of file
+{"null": 5.892551213683755}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4681.json
index e9c8a657160..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4681.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4681.json
@@ -1 +1 @@
-{"ATRIPLA": 7.327498114953578, "null": 1.0041057705130856}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4682.json
index de72f3f355b..f1db876b2b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4682.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4682.json
@@ -1 +1 @@
-{"ADVAGRAF": 45.82340584018013, "ALEMTUZUMAB": 14.16225761455937, "ARANESP": 5.013823535790412, "AZATHIOPRINE": 19.57229845532473, "BASILIXIMAB": 237.7298029655598, "CELLCEPT": 76.43006948542025, "CICLOSPORIN": 73.96579122334492, "IPILIMUMAB": 7.308882660852478, "KEYTRUDA": 1.924372317237257, "MYCOPHENOLATE": 70.929800746366, "RAPAMUNE": 70.55575082485579, "SIMULECT": 453.1409148085539, "SOLIRIS": 14.985101057727126, "TACROLIMUS": 43.66762927488129}
\ No newline at end of file
+{"1": 77.68403086713583, "ABASAGLAR": 2.3710292484164674, "ABILIFY": 0.472606106810352, "AFINITOR": 2.0054278729503, "AIMOVIG": 2.208848699579594, "APIXABAN": 0.8185275958488992, "ARAVA": 0.2050327461767593, "ATRIPLA": 0.0438397988570488, "AUBAGIO": 0.9798701286631888, "AVASTIN": 0.7055954600350806, "BETMIGA": 2.2741210454741028, "BEVACIZUMAB": 0.4346675825302497, "BIKTARVY": 1.962586575773504, "BONVIVA": 2.456956915383216, "BOSULIF": 2.550526363235168, "BRINTELLIX": 1.9696202776435476, "BUDESONIDE": 0.7840629984022617, "BUPRENORPHINE": 0.778249163525909, "BYDUREON": 1.5005013185827882, "BYETTA": 1.9966560983329096, "CABOMETYX": 1.970164845343846, "CELLCEPT": 0.4989718389546007, "CHAMPIX": 4.416052141635959, "CIMZIA": 0.2987178161761796, "CIRCADIN": 4.706691963483168, "CLOPIDOGREL": 1.2641137829561733, "COAPROVEL": 1.029933057664551, "COMBIVIR": 1.6681566117823503, "COMIRNATY": 0.3015771477149531, "COSENTYX": 0.3503099598526367, "CYMBALTA": 0.7871971300475266, "CYTARABINE": 0.5009111171804035, "DEXAMETHASONE": 0.461864541978742, "DUAKLIR": 32.581086240564545, "DULOXETINE": 1.5509424648206305, "ELIQUIS": 0.8550115483655767, "ELLAONE": 3.8110036848793216, "ENBREL": 0.5429116530899226, "ENTRESTO": 1.0150604484090142, "ENTYVIO": 4.681531096238503, "ESBRIET": 3.6950198829615095, "ESMYA": 3.3194948905355632, "ESOMEPRAZOLE": 2.1443591543183342, "EUCREAS": 4.133520620783561, "EVISTA": 1.310801025900005, "EXFORGE": 0.6066129304452185, "EXJADE": 1.3748290370135057, "FASLODEX": 0.5047278886323583, "FENTANYL": 0.389451215131587, "FORSTEO": 1.787433104538953, "FORXIGA": 1.8445824244991131, "FULVESTRANT": 0.7956965044881987, "GALAFOLD": 3.17188018200651, "GALVUS": 1.6785384770944765, "GARDASIL": 0.4192672711912457, "GENVOYA": 3.347392160246422, "HUMALOG": 0.1688395362658506, "HUMIRA": 1.2819031229552555, "IBRANCE": 1.3502226895244582, "IBUPROFEN": 0.4174080514919216, "INFANRIX": 2.259873552504024, "INLYTA": 1.5085279524440165, "INSULIN": 0.2842191455835748, "ISENTRESS": 1.0236377591384798, "JAKAVI": 1.45843927905383, "JANUMET": 2.490324040676283, "JANUVIA": 2.048284719562479, "JARDIANCE": 2.132990127855373, "KAFTRIO": 2.666804060158627, "KEPPRA": 0.3985421010213406, "KEYTRUDA": 0.3281328184001037, "LANTUS": 0.3501579284454023, "LEVEMIR": 0.4520342251393272, "LIXIANA": 1.8017176244389572, "LONSURF": 0.8134923606600827, "LYNPARZA": 1.094928456697828, "LYRICA": 0.5577273607152655, "MEKINIST": 0.4488214263399442, "MELATONIN": 1.8529272439533928, "METHOTREXATE": 0.5428659146229992, "MICARDIS": 1.8787467221582936, "MODERNA": 0.3527162719066593, "MULTAQ": 0.80409056307656, "NEULASTA": 0.6719300491715305, "NEXAVAR": 0.3508847623163384, "NINLARO": 1.457102900814512, "NUCALA": 0.2955464389580889, "OFEV": 5.593090078271459, "OLANZAPINE": 0.2159142358969873, "OPSUMIT": 1.3138831181636097, "ORKAMBI": 1.7210113698809026, "OXYBUTYNIN": 6.802367778743, "OZEMPIC": 5.952825853691669, "PANTOPRAZOLE": 1.213971068573071, "PEGASYS": 0.9407962975905892, "PEGINTRON": 0.5507608633657651, "PLAVIX": 0.6134913355841611, "PREVENAR": 2.6112599940545307, "RANEXA": 3.698013240422013, "REMSIMA": 18.668820306514707, "REVATIO": 0.6809457338075333, "RINVOQ": 0.6073267156595372, "ROACTEMRA": 0.7505935654737647, "ROTATEQ": 6.612124913330795, "RUBRACA": 1.167060200000429, "RYBELSUS": 12.219614862688434, "SAXENDA": 9.188334633323032, "SHINGRIX": 0.4467963793692337, "SILDENAFIL": 1.0868696909646316, "SIMPONI": 0.1951916389621043, "SPIKEVAX": 0.2331088351812249, "SPRYCEL": 1.1099481026048508, "STELARA": 0.3123837735631437, "STIVARGA": 0.4693483940663435, "STRIBILD": 0.3557656170947212, "SUTENT": 4.165876258667662, "TAGRISSO": 0.8252405479253139, "TAMIFLU": 0.4247610803848692, "TASIGNA": 0.5458936294738646, "TEDUGLUTIDE": 24.34308121387681, "TOUJEO": 1.0899732256517525, "TOVIAZ": 1.8111195196245249, "TOZINAMERAN": 0.6747105397648294, "TRACLEER": 0.5245749443947684, "TRELEGY": 0.6636924630000006, "TREMFYA": 0.6717516510801248, "TRIUMEQ": 3.035998592875633, "TRULICITY": 12.78345732995159, "TRUVADA": 0.0536639101157425, "TWINRIX": 0.7645224382274967, "VAXZEVRIA": 0.4285031276601818, "VELTASSA": 7.529590808600435, "VICTOZA": 5.204700462311612, "VIMPAT": 1.260873177747663, "VOTRIENT": 1.6579286474690846, "XARELTO": 0.6785935201024944, "XELJANZ": 2.3787364226860657, "XOLAIR": 0.3094812338545779, "XTANDI": 1.593582297834763, "ZEJULA": 5.575998262318844, "ZOSTAVAX": 0.3314619282937743, "ZYPREXA": 0.2961586300589834, "null": 1.690628150800625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4683.json
index f4c3001f3ab..31839c5ffcd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4683.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4683.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 47.38951551940746, "CARMUSTINE": 173.3695267637119, "CICLOSPORIN": 6.348507675249137, "DEXAMETHASONE": 9.443932765713411, "GANCICLOVIR": 56.73331181658339, "PEGASYS": 3.1353055812921675, "RITUXIMAB": 16.87453514401889}
\ No newline at end of file
+{"SIMPONI": 203.5747351817641}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4684.json
index 3d9c84739eb..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4684.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4684.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 8.117481577300529, "AMIKACIN": 95.87163851363572, "ANIDULAFUNGIN": 74.67587544324111, "ASPARAGINASE": 7.15072821700264, "BASILIXIMAB": 28.51725129953702, "BORTEZOMIB": 33.79957877498846, "BUSULFAN": 36.0755318906041, "CELLCEPT": 3.8202099405616106, "CICLOSPORIN": 10.273127245958964, "COLISTIMETHATE": 171.0713704104597, "CYTARABINE": 13.35309864921058, "DEXAMETHASONE": 10.976030207850355, "JARDIANCE": 2.844029121903007, "KEPPRA": 1.4345883743536396, "LEVOFLOXACIN": 3.361512230636813, "METHOTREXATE": 2.610137132189445, "MYCOPHENOLATE": 33.60958885421392, "RITUXIMAB": 5.662584519829539, "SOLIRIS": 7.068295718307272, "TIGECYCLINE": 173.65006107216314}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4685.json
index ed9ef96e659..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4685.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4685.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 17.566062512342242, "ASPARAGINASE": 42.801394379308704, "BUSULFAN": 17.184254697535707, "CELLCEPT": 12.720291964196132, "CLOFARABINE": 136.05771328017923, "CYTARABINE": 22.266361062781044, "DEXAMETHASONE": 11.051284174282197, "RITUXIMAB": 14.637567154789684}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4686.json
index c76e35896a8..56b15d1a98f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4686.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4686.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 112.63064890491444}
\ No newline at end of file
+{"KEPPRA": 9.799089132133316, "OLANZAPINE": 30.208888592847487, "null": 2.469287145042004}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4687.json
index 440f9ceea56..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4687.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4687.json
@@ -1 +1 @@
-{"ABATACEPT": 9.61221184378673, "ADALIMUMAB": 5.03561976091076, "ANAKINRA": 27.68503273740249, "APREMILAST": 18.174431140073462, "ARAVA": 18.66581368085681, "ATRIPLA": 1.2365671188131684, "BENLYSTA": 3.369721812508712, "BYETTA": 1.849397368703295, "CIMZIA": 4.018604794216641, "COSENTYX": 1.0182351570029566, "ENBREL": 9.178121599585564, "EVISTA": 3.085781417042667, "FORSTEO": 1.9036383389410487, "HIZENTRA": 1.9398157629850945, "HUMALOG": 1.2191853335752998, "HUMIRA": 5.858604215554467, "HYDROCORTISONE": 6.292799886246887, "IBRANCE": 1.2763134004725367, "JANUMET": 1.017652945513028, "JANUVIA": 2.722173967592781, "JARDIANCE": 1.595292441672299, "LANTUS": 3.192065933464588, "LEVEMIR": 1.5789805084273016, "NOVOSEVEN": 4.52778934410037, "OMALIZUMAB": 1.1391464319073286, "OPSUMIT": 1.792489409855731, "RINVOQ": 2.4267527637859208, "SAXENDA": 1.4051088704398815, "SIMPONI": 11.68139631167842, "STELARA": 3.203501352058184, "TRACLEER": 1.2339863016289223, "TRELEGY": 2.0570595442127053, "TREMFYA": 6.179317218656493, "VICTOZA": 2.0913548134192794, "XELJANZ": 5.018296032129474, "ZOSTAVAX": 8.676798999757185}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4688.json
index f63fcbc1a4d..d30f58fb8f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4688.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4688.json
@@ -1 +1 @@
-{"ENBREL": 6.484079502840394, "SUBOXONE": 7.416733049002116, "XELJANZ": 5.358948337671149, "null": 3.025392311614878}
\ No newline at end of file
+{"null": 2.2827141847125403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4689.json
index eaa6584bb70..8d493b97259 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4689.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4689.json
@@ -1 +1 @@
-{"AUBAGIO": 1.833396542632978, "BENLYSTA": 2.768289005750882, "CIMZIA": 4.767332042148009, "ELIQUIS": 1.7609348258765058, "FORSTEO": 1.914807724137846, "HIZENTRA": 5.8288378240947525, "HUMIRA": 4.66465344599152, "IBRANCE": 3.090937407224915, "JANUMET": 6.229673959581141, "JANUVIA": 5.599579872559818, "JARDIANCE": 3.520265529217454, "LANTUS": 5.001206293947275, "LEVEMIR": 5.214745948474147, "NAGLAZYME": 9.440127909780838, "OPSUMIT": 1.866880622721576, "RINVOQ": 14.051546388580569, "SIMPONI": 18.93369338510496, "STELARA": 5.823361416734164, "TRELEGY": 6.974465800337878, "TREMFYA": 5.680464071656886, "XELJANZ": 11.376002177893408, "ZOSTAVAX": 6.680789086079987, "null": 1.2612836149705784}
\ No newline at end of file
+{"null": 9.174218911603552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/469.json
index d4efa81c5ee..367d1514351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/469.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/469.json
@@ -1 +1 @@
-{"ADVATE": 1504.9310023749174}
\ No newline at end of file
+{"CICLOSPORIN": 14.509842339879834, "CYTARABINE": 47.05986632481543, "null": 0.5378733080244116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4690.json
index ea9f999b30f..27d9d70a3bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4690.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4690.json
@@ -1 +1 @@
-{"BRIDION": 197.39885357939272, "CLOPIDOGREL": 3.8459194677099817, "IBUPROFEN": 11.877066658304782, "LEVOFLOXACIN": 5.746158934209714, "MIDAZOLAM": 16.56913123992617, "null": 3.9023465109457542}
\ No newline at end of file
+{"JANUMET": 851.614624534523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4691.json
index ad13a1c3ae0..78bac774d3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4691.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4691.json
@@ -1 +1 @@
-{"CELLCEPT": 37.6837700343522, "JARDIANCE": 18.06378038793672, "null": 1.5164758705851222}
\ No newline at end of file
+{"null": 1.3931600667202215}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4692.json
index 053e3655ddb..61e754e6d69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4692.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4692.json
@@ -1 +1 @@
-{"ENBREL": 84.67629880236318}
\ No newline at end of file
+{"COMIRNATY": 0.2265310862432097, "CYMBALTA": 0.9164709124368796, "ENTRESTO": 5.647244532364818, "FORSTEO": 2.2533251950915405, "FORXIGA": 8.179269776519606, "IRBESARTAN": 10.47750429717237, "JARDIANCE": 5.019560120220211, "OLANZAPINE": 2.7308819692231885, "PEGASYS": 1.7138916085738016, "PEGINTRON": 2.172692381010178, "ROTATEQ": 21.33518026677384, "SPIKEVAX": 0.3528302287316284, "SUTENT": 5.14031145281826, "SYNAGIS": 8.338446272164388, "TRULICITY": 4.781537736322375, "VAXZEVRIA": 0.1171903853633181, "null": 0.9901171019674202}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4693.json
index 2cb6b17825f..a24fc24e095 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4693.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4693.json
@@ -1 +1 @@
-{"APIXABAN": 6.105948595034922, "ATRIPLA": 1.9275402723727155, "BUPIVACAINE": 93.82169501573098, "EVISTA": 30.863447269862174, "MEPOLIZUMAB": 11.514333265814438, "NAGLAZYME": 47.95198316963607, "SPINRAZA": 19.4294991677899, "ZOSTAVAX": 4.545257189281386, "null": 1.4543451903632858}
\ No newline at end of file
+{"null": 1.2565735543080117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4694.json
index 887c1a64b1b..0fab92f49b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4694.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4694.json
@@ -1 +1 @@
-{"LEVODOPA": 1272.462204249185}
\ No newline at end of file
+{"PEGINTRON": 15.2184793924201, "null": 2.4775629249880864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4695.json
index bcfc7cd488e..8d5ab0004a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4695.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4695.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 9.291289701054849, "TRELEGY": 12.207265587748717, "null": 5.231059677944292}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4696.json
index db401ef1141..95973d3a731 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4696.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4696.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 158.2656764770822, "DAPAGLIFLOZIN": 24.689699869269067, "ENOXAPARIN": 27.204020174561137, "OLANZAPINE": 6.417893443804156, "PLAVIX": 12.721136889703276, "TICAGRELOR": 220.60996919041324, "ZOSTAVAX": 17.81219378337435}
\ No newline at end of file
+{"VORICONAZOLE": 921.6795302682484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4697.json
index b6324762bb6..221e2fe6f40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4697.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4697.json
@@ -1 +1 @@
-{"ANORO": 3.283541057763978, "APIXABAN": 3.0717015409436903, "ATAZANAVIR": 2.9753748982531047, "BIVALIRUDIN": 34.98619302559191, "BRILIQUE": 1.098306631445343, "BUPIVACAINE": 6.596760473311735, "CAPECITABINE": 1.734910271931254, "CIRCADIN": 14.852121223881658, "CLOPIDOGREL": 157.08693147264688, "EDOXABAN": 21.588587890473065, "EFAVIRENZ": 4.895999838538571, "EFIENT": 16.698201360135137, "ELIQUIS": 3.0008960257388377, "ELLAONE": 5.507525391582116, "ENOXAPARIN": 16.890657382638054, "ENVARSUS": 48.53508073081731, "ESMYA": 17.051385948802324, "IBUPROFEN": 1.5685457476574227, "INCRUSE": 12.478805454018644, "KALETRA": 1.44239114337874, "LIXIANA": 2.7724472863580587, "PLAVIX": 21.651846697026063, "PRASUGREL": 92.53361777587648, "RANEXA": 4.589921357920211, "RIVAROXABAN": 11.36288257218647, "TACROLIMUS": 8.395399340523921, "TICAGRELOR": 199.4374895009144, "TRELEGY": 5.71441106082268, "XARELTO": 11.869543284749875}
\ No newline at end of file
+{"VFEND": 93.42640505607532, "VORICONAZOLE": 1698.8237236018088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4698.json
index eec02b2d9b3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4698.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4698.json
@@ -1 +1 @@
-{"null": 4.000509736211133}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4699.json
index 6aebcc7b648..3b4668f917a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4699.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4699.json
@@ -1 +1 @@
-{"OLANZAPINE": 32.27977575299081, "null": 2.005000870635928}
\ No newline at end of file
+{"ABILIFY": 0.141319400003291, "ADALIMUMAB": 0.0311258315620136, "ADCIRCA": 5.008542459656376, "ADEMPAS": 6.115299737631473, "AFINITOR": 1.4943192947576762, "AIMOVIG": 2.2407269747283283, "ALEMTUZUMAB": 2.7440354566123477, "ALIMTA": 0.5280613215102407, "AMBRISENTAN": 6.205495925250792, "ANAKINRA": 0.9564289820178152, "APREPITANT": 0.5268129432518689, "APROVEL": 1.921466259815443, "ARAVA": 0.0333666716035128, "ARIPIPRAZOLE": 0.1908093948447917, "ARZERRA": 4.12308805517138, "AUBAGIO": 0.6778776936010287, "AVAMYS": 0.29819487364528, "AVASTIN": 1.0289613475604311, "BENLYSTA": 0.7115295478246794, "BETMIGA": 0.8802689749611101, "BEVACIZUMAB": 0.6881142897938166, "BEXSERO": 1.2748824428414618, "BEXTRA": 4.442430610325446, "BIKTARVY": 0.4262686464962502, "BONVIVA": 0.8518512590658799, "BOSENTAN": 2.3685452636759696, "BRIDION": 3.529586010827188, "BRINTELLIX": 0.5956946088664176, "BUDESONIDE": 0.65424676445011, "BUPRENORPHINE": 0.2349648253529933, "BYDUREON": 0.461248629476963, "BYETTA": 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"XOLAIR": 3.7167230737031383, "XTANDI": 0.6549774053629117, "ZOSTAVAX": 0.2301291945993231, "ZYPREXA": 0.0927040032584152, "null": 2.339500132985182}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/47.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/47.json
index 106d2923fae..e36ac4c095e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/47.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/47.json
@@ -1 +1 @@
-{"STELARA": 88.12870733460751}
\ No newline at end of file
+{"null": 0.9814585982551852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/470.json
index ee9eeb9425d..cf73911d6f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/470.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/470.json
@@ -1 +1 @@
-{"ADVATE": 709.2331216936611, "ELOCTA": 1392.4633636192832, "HELIXATE": 2526.0794837119424, "HUMAN": 25.0229386184022, "KOGENATE": 3799.027533412679, "KOVALTRY": 1329.062886870339, "OCTOCOG": 4529.024532274634, "null": 2.126420140360335}
\ No newline at end of file
+{"null": 0.8623740905996042}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4700.json
index 6ca7efa0e0b..6fa35079d13 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4700.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4700.json
@@ -1 +1 @@
-{"ARAVA": 2.131296654253137, "CYMBALTA": 1.644582494536215, "OLANZAPINE": 4.762087110553849, "null": 1.280079754701562}
\ No newline at end of file
+{"SORAFENIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4701.json
index c88b71130b9..5f1b05b26df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4701.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4701.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 49.36745107373852, "CLOPIDOGREL": 11.96470698346977, "COMIRNATY": 1.1330044166524726}
\ No newline at end of file
+{"CHAMPIX": 1.6791131597335949, "COMIRNATY": 0.2695521356916045, "FENTANYL": 2.239873419174073, "GARDASIL": 1.9245718364242463, "LANTUS": 0.9700803442657054, "OLANZAPINE": 2.2602944877163456, "PREGABALIN": 23.05354771617104, "SPIKEVAX": 0.3176509628084326, "SUBOXONE": 3.329928055283052, "TOZINAMERAN": 0.2606679564859567, "VAXZEVRIA": 0.0657384902218437, "null": 3.2372559731407606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4702.json
index 406836e45a8..88d37354c7a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4702.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4702.json
@@ -1 +1 @@
-{"SPIKEVAX": 34.9703162556709}
\ No newline at end of file
+{"BENZODIAZEPINES": 129.36827053141727, "BRIVIACT": 42.01311000489026, "BUSULFAN": 7.638406024092768, "COMIRNATY": 0.0608654331857019, "FYCOMPA": 64.32892925188159, "GARDASIL": 2.3153184668312807, "KEPPRA": 58.978940357867394, "LACOSAMIDE": 107.43070588901185, "LEVETIRACETAM": 50.58469381913426, "VIMPAT": 32.42546357454082, "null": 1.1517938885811283}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4703.json
index d20aab786e2..54e8a7188a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4703.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4703.json
@@ -1 +1 @@
-{"ABACAVIR": 1.7555439726992872, "ADALIMUMAB": 1.1734219184969594, "AFINITOR": 1.2163952930053736, "AMINOSALICYLIC": 2.227604997213776, "APIDRA": 1.307574560209738, "ARANESP": 2.792296422174614, "ARAVA": 1.5823300464221473, "AUBAGIO": 1.188126317284848, "BENLYSTA": 4.011493791593085, "BOSULIF": 6.593079267966624, "CABOMETYX": 1.9299495070616577, "COMBIVIR": 3.758538240824844, "DARZALEX": 3.033870076213724, "DEXAMETHASONE": 1.5086508478961054, "ENBREL": 2.0135594067108755, "ENTRESTO": 1.1709674135917665, "ENTYVIO": 1.02538517557642, "EXJADE": 1.6348851397494486, "FASLODEX": 2.064729100183572, "FULVESTRANT": 3.21337529523442, "HUMIRA": 3.322679119811636, "IBRANCE": 7.737323458994262, "JAKAVI": 2.139621419482668, "JANUMET": 1.410012845020434, "KEYTRUDA": 1.2094241690296763, "KISQALI": 3.828933922779064, "LEMTRADA": 3.621720089890224, "LUTATHERA": 10.53113452785168, "LYNPARZA": 2.688679409913006, "MEPOLIZUMAB": 5.055496838437614, "MICARDIS": 1.6311815653419184, "NEULASTA": 4.92181843772609, "NINLARO": 11.40718050355891, "NPLATE": 1.9366989571026283, "OCALIVA": 11.790712629326505, "PEGASYS": 2.6750691600372205, "PEGINTRON": 1.7310964284839965, "PLUVICTO": 34.39272569593107, "REVLIMID": 5.466539878105095, "RINVOQ": 3.9547856204719793, "RUBRACA": 14.57198169930636, "SIMPONI": 1.0605019135612348, "SOLIRIS": 13.700520684656396, "SPRYCEL": 1.9613371053970972, "STIVARGA": 1.8088363787973172, "SUTENT": 1.8330684172644152, "VENETOCLAX": 7.153499136707326, "VOTRIENT": 1.426761653276463, "XELJANZ": 2.733926354084012, "XOFIGO": 5.109347993959273, "XTANDI": 1.260838133891354, "ZYPREXA": 1.1552387774425514, "null": 1.191257349848574}
\ No newline at end of file
+{"ATAZANAVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4704.json
index bf4b22bec9d..b81c887d1bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4704.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4704.json
@@ -1 +1 @@
-{"null": 2.7501301876753126}
\ No newline at end of file
+{"ADCIRCA": 119.50748750356352, "SOMATROPIN": 148.3289695208738, "THIOTEPA": 679.6024211412794, "null": 1.0329931675297066}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4705.json
index 7ac60329288..f6148db4597 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4705.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4705.json
@@ -1 +1 @@
-{"SPIKEVAX": 12.24010533147733}
\ No newline at end of file
+{"ATRIPLA": 0.6502707132537366, "CELLCEPT": 17.103564704192642, "CICLOSPORIN": 39.90695710379604, "COMIRNATY": 0.2704785643150532, "SOMATROPIN": 77.75742512517103, "SPIKEVAX": 0.3085887433862997, "TRUVADA": 1.9029750298411148, "null": 0.6072265086279852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4706.json
index 6d1a2432522..c6835180ec8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4706.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4706.json
@@ -1 +1 @@
-{"null": 5.198964971256344}
\ No newline at end of file
+{"null": 3.1560025990362823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4707.json
index c246d5db516..ccbe8310f34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4707.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4707.json
@@ -1 +1 @@
-{"GARDASIL": 66.52434329736816, "null": 2.2990917653458}
\ No newline at end of file
+{"null": 3.612151837161976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4708.json
index 56608465f92..838e0fd9bed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4708.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4708.json
@@ -1 +1 @@
-{"COMIRNATY": 4.22588558148384, "SPIKEVAX": 1.2348939561664307, "VAXZEVRIA": 2.405751919591685}
\ No newline at end of file
+{"AZATHIOPRINE": 385.1714818731349, "CYTARABINE": 107.95678939511905, "null": 0.4079337498083747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4709.json
index aa85803d90f..5797b9ef791 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4709.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4709.json
@@ -1 +1 @@
-{"CHAMPIX": 3.0727936042571256, "COVID19": 3.237443169633215, "LANTUS": 1.4121836604246012, "MEPOLIZUMAB": 9.844129040870063, "SIMPONI": 3.1570523568812368, "TOZINAMERAN": 4.040149543526483, "ZOSTAVAX": 3.050958584191286}
\ No newline at end of file
+{"KEPPRA": 3.4281545341271635, "null": 56.56747290290325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/471.json
index f90c5cea544..e69d5fb8549 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/471.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/471.json
@@ -1 +1 @@
-{"ADVATE": 1794.795778416135, "KOGENATE": 4233.530740644854}
\ No newline at end of file
+{"ANAKINRA": 893.1091123770897, "null": 0.3448040397031988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4710.json
index 47a17cd2322..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4710.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4710.json
@@ -1 +1 @@
-{"null": 1.3959986505165196}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4711.json
index e57ecb5041e..54e6f432cdd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4711.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4711.json
@@ -1 +1 @@
-{"LANTUS": 31.081846666495817, "NOVORAPID": 29.727780283293317, "PLEGRIDY": 49.56307188959267}
\ No newline at end of file
+{"null": 2.158057427192276}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4712.json
index e193d6a01e2..536d51d6a63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4712.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4712.json
@@ -1 +1 @@
-{"SAXENDA": 362.8339976282431}
\ No newline at end of file
+{"null": 3.484806290653003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4713.json
index d6583119478..a8decf170f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4713.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4713.json
@@ -1 +1 @@
-{"TOZINAMERAN": 3.983617823266553, "null": 1.4966123123449866}
\ No newline at end of file
+{"COMIRNATY": 0.391979901185851, "null": 1.251475163937511}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4714.json
index 1f11b8ec969..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4714.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4714.json
@@ -1 +1 @@
-{"SUTENT": 6.918533337798009, "null": 1.369006186723054}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4715.json
index 32ca5dda61c..f74f266da79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4715.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4715.json
@@ -1 +1 @@
-{"null": 1.170753833896769}
\ No newline at end of file
+{"LANTUS": 14.37343277918957, "null": 0.4275639626801554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4716.json
index 63ce93aee11..3982c4303f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4716.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4716.json
@@ -1 +1 @@
-{"ZOSTAVAX": 13.157699378137997, "null": 2.0063382529418163}
\ No newline at end of file
+{"null": 0.6842411932383017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4717.json
index 198442d935a..dca6a956fcb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4717.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4717.json
@@ -1 +1 @@
-{"null": 2.413910384021141}
\ No newline at end of file
+{"null": 3.857120493859071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4718.json
index a14854e9a0c..c1854602ff2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4718.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4718.json
@@ -1 +1 @@
-{"ALIMTA": 3.733165771183845, "AMGEVITA": 90.57457375383964, "AVAMYS": 2.397789322153405, "BEOVU": 4.228847533318706, "BUDESONIDE": 10.119016008498214, "BUPRENORPHINE": 1.0170321161832518, "CAPECITABINE": 2.599719125318074, "CARBIDOPA": 17.266409916684143, "CHAMPIX": 1.876347925855374, "DOCETAXEL": 2.313130989077009, "ENBREL": 1.2583471819992629, "EVOLOCUMAB": 77.51671038697926, "EYLEA": 8.312456745513204, "FASLODEX": 2.7621844351599982, "FLUTICASONE": 23.424075558643075, "FULVESTRANT": 1.5251937756245455, "HERCEPTIN": 2.6089338111470703, "IBRANCE": 3.984079348091146, "IKERVIS": 111.14353348151823, "KAFTRIO": 1.3552732003239576, "KISQALI": 4.072918278244662, "MEPOLIZUMAB": 1.828158641689859, "METHOTREXATE": 2.662963271355986, "MMRVAXPRO": 1.6594665017567114, "NEVANAC": 19.52864943822285, "NUCALA": 10.850182332376242, "OMALIZUMAB": 2.08615339088857, "OPATANOL": 52.36524843309823, "PANTOPRAZOLE": 2.0005300337806, "PEMETREXED": 2.560465838973916, "SUBOXONE": 1.127077885607234, "SUTENT": 2.35558299120903, "TOZINAMERAN": 1.133757297342468, "TRELEGY": 1.856308129286264, "VIAGRA": 1.2495950209547828, "XOLAIR": 2.6458595144824386, "XTANDI": 1.2393837800227503, "ZOSTAVAX": 1.0337744655674608, "null": 1.3236291532643485}
\ No newline at end of file
+{"ABACAVIR": 125.86364401362368, "APIDRA": 2.651402355361708, "ARAVA": 0.1590827254525754, "BUPIVACAINE": 4.480334224675416, "CELLCEPT": 0.9200903116396656, "CICLOSPORIN": 0.5242630164493952, "CIMZIA": 0.3769040482206739, "COMBIVIR": 11.808092646693671, "COMIRNATY": 0.1960830729694398, "DARUNAVIR": 11.471153671176488, "DEXAMETHASONE": 1.610475855514663, "ENBREL": 2.756097755791045, "ENOXAPARIN": 2.357001440023308, "FENTANYL": 7.374970432409965, "GARDASIL": 1.136124880307518, "HUMALOG": 0.7434480398236596, "HUMAN": 5.000896459745274, "HUMIRA": 1.536353139044493, "HYDROCORTISONE": 4.203265532128063, "INSULATARD": 32.1438997235954, "INTRONA": 15.198744649563524, "KALETRA": 5.3430083497887, "KEPPRA": 2.524508255107876, "LAMIVUDINE": 4.398106692919867, "LEVEMIR": 3.14757917733095, "MIDAZOLAM": 7.8622113470239485, "NORVIR": 9.983281402854429, "NOVORAPID": 3.06326977563021, "OLANZAPINE": 0.571513109092786, "OSELTAMIVIR": 14.3726956600107, "PEGASYS": 0.2659373180659676, "PEGINTRON": 1.268343224622468, "SOLIRIS": 2.007891850605745, "SPIKEVAX": 0.0979940019821571, "SUBOXONE": 1.694106562680121, "TAMIFLU": 5.341308159496689, "TOZINAMERAN": 0.2278809006271454, "TRACTOCILE": 90.95769082566837, "TRUVADA": 0.1760104201108144, "VAXZEVRIA": 0.0303435214257716, "VIREAD": 2.3081138750572574, "ZYPREXA": 1.03594397648085, "null": 1.408855344677928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4719.json
index 04f83c0802b..10794e869bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4719.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4719.json
@@ -1 +1 @@
-{"null": 2.119843710264686}
\ No newline at end of file
+{"ARIPIPRAZOLE": 66.21475681325335, "CICLOSPORIN": 5.282332780131777, "ISENTRESS": 53.2821130758034, "null": 2.060432570470258}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/472.json
index d8bc5ce68be..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/472.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/472.json
@@ -1 +1 @@
-{"ELIQUIS": 115.52386320062904}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4720.json
index 25dcd5a99a7..3ffea364402 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4720.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4720.json
@@ -1 +1 @@
-{"COMIRNATY": 2.982256622721679, "SPIKEVAX": 1.187980605066611}
\ No newline at end of file
+{"ABILIFY": 13.225293047437852, "ASPARAGINASE": 14.7398836433327, "BUPIVACAINE": 10.923902199153185, "BUPRENORPHINE": 6.319591394235618, "CICLOSPORIN": 4.129889388257717, "CIMZIA": 1.252368728601999, "CLOPIDOGREL": 1.3099923198080212, "COMBIVIR": 31.476179164783108, "DEXAMETHASONE": 5.37767523036257, "FENTANYL": 6.855978502288396, "JARDIANCE": 1.8143716543644055, "KALETRA": 6.998166371588082, "KEPPRA": 2.735307263665935, "LEVEMIR": 7.332867073113737, "LEVETIRACETAM": 3.0915571262775283, "NEVIRAPINE": 34.31511743597952, "NOVORAPID": 4.266942877509874, "RECOMBINANT": 977.5496199059312, "SOLIRIS": 3.5170824529250417, "SUBOXONE": 7.34344764637757, "null": 2.0204790267461936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4721.json
index e5a6b1f982e..14f8d5fa251 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4721.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4721.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 4.050284222857967, "COMIRNATY": 6.564920227755662, "SPIKEVAX": 1.767742960315883, "TOZINAMERAN": 1.3445463236166748}
\ No newline at end of file
+{"AUBAGIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4722.json
index 46d6db1ddf3..d719fdd51e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4722.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4722.json
@@ -1 +1 @@
-{"COMIRNATY": 2.7595088998447697, "SPIKEVAX": 1.4205359158666668}
\ No newline at end of file
+{"ATAZANAVIR": 37.38641258305063, "BUPIVACAINE": 120.45978787072332, "FENTANYL": 35.07848826987512, "MIDAZOLAM": 32.37601590793237, "null": 4.743549049593492}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4723.json
index a419b99e953..50ff33f8923 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4723.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4723.json
@@ -1 +1 @@
-{"ABACAVIR": 2.256909516030749, "ACTOS": 3.958809395203219, "ACTRAPID": 2.5535677290363106, "ADENURIC": 5.490190426958176, "AGENERASE": 18.69573347936737, "AMIKACIN": 1.4120047732222736, "APIDRA": 1.0350649354260042, "APREMILAST": 1.647288212821821, "APROVEL": 8.858199242854303, "ATAZANAVIR": 1.3939710256005489, "BARACLUDE": 9.605478540840526, "BETMIGA": 1.0045146757949692, "BIKTARVY": 2.818647919224698, "BYETTA": 1.0059264167955548, "CANAGLIFLOZIN": 7.561294628413499, "CELECOXIB": 3.737386679172201, "COAPROVEL": 11.38974419366384, "COMBIVIR": 4.102785800585461, "COMPETACT": 78.00036413067367, "CRIXIVAN": 13.556417406107396, "DAPAGLIFLOZIN": 5.598691253071434, "DAPTOMYCIN": 4.658532419402796, "DARUNAVIR": 3.4829111833959803, "DOLUTEGRAVIR": 4.342632317561691, "DULAGLUTIDE": 2.6397498231605625, "DUOPLAVIN": 35.72516020539575, "EFAVIRENZ": 3.869819696208984, "EFFICIB": 85.40520449294411, "EMPAGLIFLOZIN": 10.105999062525663, "EMTRICITABINE": 4.4671318464322045, "EMTRIVA": 4.626745267934338, "ENTECAVIR": 6.878527305442215, "EPIVIR": 15.513690838318295, "ESOMEPRAZOLE": 4.460404056707669, "EUCREAS": 54.0076132996157, "FORXIGA": 3.777293977954274, "GALVUS": 2.8842817085669443, "GENVOYA": 2.432816034194554, "GLIBENCLAMIDE": 8.31553636135406, "GLUCAGON": 18.29339663212248, "HEPSERA": 1.3192000665986932, "IBUPROFEN": 2.586924139039233, "INDINAVIR": 10.615151331617422, "INSULATARD": 5.741622961994821, "INSULIN": 1.3230728462385803, "INVIRASE": 13.189574486225942, "INVOKANA": 4.822680612783729, "IRBESARTAN": 8.469649436089473, "ISENTRESS": 1.2715626482583036, "JANUMET": 13.0537400613629, "JANUVIA": 2.829537625628609, "JARDIANCE": 4.446969200970843, "KALETRA": 5.48629938283975, "KARVEZIDE": 11.08753621334067, "LAMIVUDINE": 11.65414318888806, "LIRAGLUTIDE": 2.663629836207467, "METFORMIN": 37.51443785708738, "MICARDIS": 1.2673799089226063, "MICARDISPLUS": 7.595427151077852, "MIDAZOLAM": 1.2769485927673143, "NEVIRAPINE": 3.561322697959865, "NORVIR": 2.1900375161912287, "NOVONORM": 8.07938423012479, "OZEMPIC": 4.055427963833002, "PANTOPRAZOLE": 2.646179865189945, "PRITOR": 11.059916099594156, "RASILEZ": 1.461612094137502, "REPAGLINIDE": 20.635407602360583, "RYBELSUS": 1.302806679390702, "SAQUINAVIR": 30.76625312782692, "SITAGLIPTIN": 21.52830886033204, "SPIRONOLACTONE": 1.5212248330285598, "STAVUDINE": 59.73239803503783, "SUSTIVA": 10.085088378464995, "TELMISARTAN": 1.569811387712367, "TENOFOVIR": 3.481036080947576, "TIVICAY": 2.584505602748674, "TOBRAMYCIN": 2.488585383059465, "TRULICITY": 1.1339710238278229, "VELMETIA": 83.63659740336495, "VEMLIDY": 4.63161942658897, "VICTOZA": 1.760583284440638, "VILDAGLIPTIN": 11.333772610235249, "VIRAMUNE": 3.731626853255287, "VIREAD": 5.014528573869841, "XARELTO": 2.555879522454513, "XIGDUO": 76.28632593236019, "ZERIT": 112.65864287560146, "ZOMARIST": 61.4950458281488, "null": 4.654093293193839}
\ No newline at end of file
+{"ABACAVIR": 0.8278328452294702, "ABILIFY": 3.3975274656218546, "ACTRAPID": 2.909382303100484, "ADALIMUMAB": 0.1912712378817564, "AERIUS": 1.2944423993805512, "AIMOVIG": 0.2640573435352643, "ALISKIREN": 2.613055227838435, "ANTIBIOTIC": 6.945300574762279, "ANTIBIOTICS": 1.865198562235805, "APIDRA": 1.257990057762552, "APTIVUS": 5.654519907981118, "ARANESP": 0.1868941654201049, "ARAVA": 0.6601700841507222, "ARIPIPRAZOLE": 1.6139336669203987, "ASPARAGINASE": 0.7536396481203066, "ATAZANAVIR": 5.005933676692155, "ATOSIBAN": 50.82404342107393, "ATRIPLA": 0.0748195712977956, "AUBAGIO": 0.1472697633296165, "AZATHIOPRINE": 3.7876762676410816, "BARACLUDE": 1.26327106041193, "BENLYSTA": 0.1547312994309411, "BENZODIAZEPINE": 3.3808892362155145, "BENZODIAZEPINES": 3.3457231214169907, "BIKTARVY": 1.500736008726904, "BRINTELLIX": 0.3183960631367896, "BRIVARACETAM": 2.727986055011248, "BUDESONIDE": 0.8469925961680188, "BUPIVACAINE": 6.072165798039262, "BUPRENORPHINE": 15.552875092357802, "BUVIDAL": 6.855405136629372, "BYETTA": 0.1305820170156182, "CELLCEPT": 0.4248157059407708, "CEPHALOSPORIN": 39.82482979404303, "CHAMPIX": 0.0612156594249055, "CHLORHEXIDINE": 4.142874731469938, "CICLOSPORIN": 1.643516099188437, "CIMZIA": 0.2549346435245057, "CINACALCET": 9.842911919899434, "CLOPIDOGREL": 0.2238570762235429, "COAPROVEL": 0.5230668255673253, "COMBIVIR": 15.014643266201118, "COMIRNATY": 0.0153173259221459, "COSENTYX": 0.06500482761442, "CRIXIVAN": 1.2308409177946689, "CYMBALTA": 0.8155961743396689, "CYTARABINE": 0.7561126417588871, "DARBEPOETIN": 3.572086143289717, "DARUNAVIR": 9.16330567227559, "DESCOVY": 1.8408118829471605, "DEXAMETHASONE": 3.670418260284831, "DEXMEDETOMIDINE": 13.070754128487645, "DOLUTEGRAVIR": 6.160317009750506, "DOXORUBICIN": 0.6528040868076022, "DULOXETINE": 1.177869434348182, "ECULIZUMAB": 7.827990452198647, "EDURANT": 3.931458941239691, "EFAVIRENZ": 7.152886455357908, "ELIQUIS": 0.0277555126093684, "EMTRICITABINE": 12.020781934089824, "EMTRIVA": 3.993836754884389, "ENFUVIRTIDE": 7.100088648845284, "ENOXAPARIN": 7.047913227351884, "ENTYVIO": 0.3162581399018991, "EPCLUSA": 0.5082122171598407, "EPIVIR": 7.530997689333515, "EPOETIN": 4.360072085638552, "ESMYA": 1.117937019437533, "ESOMEPRAZOLE": 1.3221637974917209, "EVIPLERA": 19.495186980924544, "EXFORGE": 0.3308047023683919, "EXJADE": 0.2389031885902349, "FENTANYL": 6.350611300741691, "FIASP": 0.9100570828144376, "FYCOMPA": 1.5588354989842816, "GANCICLOVIR": 0.4319960743225586, "GARDASIL": 0.3222400644812389, "GLYCOPYRRONIUM": 1.4229156500661777, "HUMALOG": 1.628418445789184, "HUMAN": 4.766632345459989, "HUMIRA": 0.1344112608045217, "HYDROCORTISONE": 1.6648321342490993, "IBUPROFEN": 0.8925542558894621, "ILOPROST": 16.425739907769593, "INFLIXIMAB": 1.2368957252449482, "INSULATARD": 8.687319405670058, "INSULIN": 3.8606507572945454, "INTELENCE": 10.041149469213378, "INTERFERON": 1.5982241567855398, "INVIRASE": 1.4501619416373768, "IRINOTECAN": 0.6865941794558058, "IRON": 12.592708703253534, "ISENTRESS": 19.543130873268037, "JANUVIA": 0.1093133177788057, "JARDIANCE": 0.0893162398336927, "KALETRA": 4.5087321968616045, "KEPPRA": 2.3194200171251835, "KIOVIG": 2.153870562547876, "KIVEXA": 4.451475981750538, "LACOSAMIDE": 3.9444909902749337, "LAMIVUDINE": 9.90235945375504, "LANTUS": 0.5080843466041431, "LATUDA": 1.0855772812681852, "LEVEMIR": 8.897600175521912, "LEVETIRACETAM": 5.635095960703141, "LEVOFLOXACIN": 0.2108542504734256, "LOPINAVIR": 4.4603940342105, "LYRICA": 0.3848785625295336, "MANNITOL": 3.0986054003782653, "MELATONIN": 0.5077706008384866, "MERCAPTOPURINE": 1.0536314582478223, "METHOTREXATE": 0.4221176411629822, "MICARDIS": 0.1868745507979619, "MIDAZOLAM": 4.222222560598248, "MMRVAXPRO": 0.3323884402922973, "MYCOPHENOLATE": 0.6891045173707631, "NALOXONE": 3.5060697833212155, "NEVIRAPINE": 12.142572455099492, "NORVIR": 10.133152246833808, "NOVORAPID": 3.101322919600807, "OLANZAPINE": 1.1721159653265985, "OMALIZUMAB": 0.1216743901643746, "OPIATES": 29.85030895051288, "OPIOIDS": 14.90641647128799, "OPSUMIT": 0.0727087714569536, "OSELTAMIVIR": 14.20124506709699, "OXYBUTYNIN": 1.185481896779025, "PACLITAXEL": 1.6654230756139428, "PANTOPRAZOLE": 1.320432108889427, "PEGASYS": 0.0821953350203896, "PEGINTRON": 0.2131017423387498, "PLEGRIDY": 0.863382438510854, "PREGABALIN": 0.6215136569371879, "PRIVIGEN": 0.6384875614477934, "PROPRANOLOL": 0.8710659113983166, "REMICADE": 2.762625401323441, "REYATAZ": 3.1554473041098103, "RIBAVIRIN": 0.2848405953211155, "RINVOQ": 0.2265556177233144, "RITUXIMAB": 0.8151151536869867, "ROACTEMRA": 0.2263941342485367, "SAXENDA": 0.5711392777945484, "SILDENAFIL": 3.8854247751640623, "SIMPONI": 0.4610915283431446, "SOLIRIS": 1.4235636596127017, "SPIKEVAX": 0.0179847359916179, "SPIRONOLACTONE": 0.7738372238051987, "STELARA": 1.2658527230362, "SUBOXONE": 24.324548621955607, "SUFENTANIL": 1.1710988738357009, "SUSTIVA": 3.8997189349624337, "TACROLIMUS": 2.2210328204057324, "TAMIFLU": 0.3001074929228798, "TELMISARTAN": 0.8851234758030508, "TENOFOVIR": 3.4396858486596025, "TOUJEO": 0.3591608858857804, "TOZINAMERAN": 0.0258307166340587, "TRACTOCILE": 20.554724924786896, "TRESIBA": 1.6962416850736692, "TRIUMEQ": 1.5180219360847351, "TRUVADA": 0.0811742808801887, "VAXZEVRIA": 0.0164052437489925, "VICTOZA": 0.3315579698232866, "VIGABATRIN": 4.969120428596721, "VIMPAT": 0.3358665044202019, "VIRACEPT": 20.004843570465844, "VIRAMUNE": 2.4677831812204265, "VIREAD": 0.90408211669689, "XOLAIR": 0.722713427427652, "ZONISAMIDE": 2.741425171075988, "ZYPREXA": 1.144055278450557, "null": 3.4051099753521488}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4724.json
index b0537d2dbc0..9dd0cfe86d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4724.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4724.json
@@ -1 +1 @@
-{"null": 1.561918659840594}
\ No newline at end of file
+{"APIDRA": 31.99287144806591, "ARAVA": 1.5932246614436805, "FENTANYL": 4.530649498833, "INSULIN": 17.03224301123976, "LANTUS": 11.48803935466787, "OLANZAPINE": 4.03452645745584, "null": 2.538700756704709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4725.json
index 3a1bc09c900..03febc92c09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4725.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4725.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 1.691437437157549, "CYMBALTA": 1.0200743391276073, "FLUTICASONE": 216.58830413682105, "GARDASIL": 6.460965124056082, "IMATINIB": 37.813715070727866, "ROTATEQ": 12.131904994862603, "TASIGNA": 6.416781284253575, "XELJANZ": 2.913422612802192, "null": 1.929211307980757}
\ No newline at end of file
+{"SUBOXONE": 88.01753734723852, "null": 1.0376736955944594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4726.json
index 663ad2c9e58..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4726.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4726.json
@@ -1 +1 @@
-{"AVANDAMET": 11.344734333160911, "AVANDIA": 16.58420049389253, "CLOPIDOGREL": 1.879935691800472, "CYMBALTA": 1.133752682598148, "ELIQUIS": 2.077785978298765, "EVENITY": 33.699373431212905, "EYLEA": 10.415320143467117, "FORXIGA": 6.77736895532869, "JARDIANCE": 3.910781484904638, "NEXAVAR": 3.2938767148953887, "PEGINTRON": 2.118287269868794, "PLAVIX": 1.8597440303390853}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4727.json
index 1a7937b7014..4413f7dad6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4727.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4727.json
@@ -1 +1 @@
-{"COVID19": 3.165761276987318, "SPIKEVAX": 1.003427077440474}
\ No newline at end of file
+{"ATOSIBAN": 2117.559489195261, "null": 1.085029270713009}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4728.json
index 8afed05afb4..f22d4181730 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4728.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4728.json
@@ -1 +1 @@
-{"TOZINAMERAN": 1.502145609732511, "null": 1.576872646756969}
\ No newline at end of file
+{"ABILIFY": 3.256793325174259, "ADVAGRAF": 29.970436453067997, "ARANESP": 1.8608477683176745, "ARIPIPRAZOLE": 1.8297796201899, "ATRIPLA": 0.1480594142375945, "AZATHIOPRINE": 13.82479246266451, "BUDESONIDE": 0.7468508756966021, "BUPIVACAINE": 15.962888098324468, "BUPRENORPHINE": 4.135604250406109, "CAPECITABINE": 2.498361696939574, "CELLCEPT": 0.8208525984344611, "CEPHALOSPORIN": 396.3152677772589, "CICLOSPORIN": 5.5070590986314, "CIMZIA": 1.0599372997761107, "CLOPIDOGREL": 1.2717829337420814, "COMBIVIR": 15.135765488134268, "COMIRNATY": 0.0949699310096967, "CYMBALTA": 0.4914190840694522, "CYTARABINE": 2.3008489458749604, "DEXAMETHASONE": 6.864727161145653, "DOLUTEGRAVIR": 11.893823751249432, "ENOXAPARIN": 16.370230812643833, "EPIVIR": 5.410604103513777, "FENTANYL": 2.7107046930707464, "GARDASIL": 0.5989929476317088, "HUMALOG": 0.950321518460143, "HUMAN": 4.505419817437125, "HYDROCORTISONE": 2.105101734585443, "INSULIN": 4.789515988164296, "ISENTRESS": 12.543304807881617, "KALETRA": 4.39548335946102, "KEPPRA": 4.649515305725992, "KIVEXA": 30.626395538135064, "LANTUS": 0.4280446507692034, "LEVEMIR": 2.078376167552061, "LEVETIRACETAM": 2.788827944786607, "METHOTREXATE": 1.2570996317577072, "MIDAZOLAM": 14.828455228149242, "MYCOPHENOLATE": 4.008145349538796, "NORVIR": 11.290556341965608, "NOVORAPID": 4.828832119411672, "OSELTAMIVIR": 29.65656131696017, "PEGASYS": 0.6055167227124312, "SILDENAFIL": 5.804947577549806, "SOLIRIS": 2.2706051188267558, "SPIKEVAX": 0.0654123890758118, "SUBOXONE": 6.464882274430163, "TOZINAMERAN": 0.2922320232541799, "TRACTOCILE": 83.26589431194269, "TRUVADA": 0.4492474308621211, "ZYPREXA": 1.462094415783613, "null": 1.9712125456433665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4729.json
index 141e04be6b9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4729.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4729.json
@@ -1 +1 @@
-{"CLADRIBINE": 354.6834325581087, "MERCAPTOPURINE": 311.60788927957253}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/473.json
index c08278e4ef6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/473.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/473.json
@@ -1 +1 @@
-{"INSULIN": 46.95654069239811}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4730.json
index 4cef060a0d3..0e9b391556a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4730.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4730.json
@@ -1 +1 @@
-{"COMIRNATY": 1.8334168561081767, "INFANRIX": 8.110883309480084, "KEPPRA": 2.3190226428362197, "LEVETIRACETAM": 5.664683744393851, "ROTASHIELD": 167.08595571253818, "SPIKEVAX": 1.094857809100268, "VAXZEVRIA": 1.1426855029598044, "ZYPREXA": 1.2783170219026074, "null": 1.987119337124836}
\ No newline at end of file
+{"COMIRNATY": 0.1355903952673149, "ENOXAPARIN": 20.502428355657493, "FENTANYL": 10.613237611772298, "GARDASIL": 4.446274376300782, "SUBOXONE": 7.182301574836217, "null": 2.1131174380002826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4731.json
index 905446f84fe..9138eb5b09e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4731.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4731.json
@@ -1 +1 @@
-{"BYETTA": 121.00273941163998}
\ No newline at end of file
+{"CICLOSPORIN": 5.985455428854646, "FENTANYL": 54.09154122548195, "GARDASIL": 3.2437543729757685, "null": 1.8015794836410703}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4732.json
index 22d310bebb2..bfa056cf2d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4732.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4732.json
@@ -1 +1 @@
-{"BYETTA": 31.393207565366254, "CICLOSPORIN": 10.021153245903974, "ELIQUIS": 2.677067177231682, "HUMIRA": 15.011547619204594, "JANUMET": 11.899209316879938, "JANUVIA": 26.279891388220648, "ROTATEQ": 149.57965230494827}
\ No newline at end of file
+{"ABILIFY": 8.861841124423377, "FENTANYL": 31.113077719085314, "SUBOXONE": 15.16748516887113, "null": 2.9299681919645977}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4733.json
index f351474a2ee..b88596f58fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4733.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4733.json
@@ -1 +1 @@
-{"ABILIFY": 12.734298551573785, "HUMALOG": 18.649890323998875, "KEPPRA": 4.936848750049724, "null": 1.6913865101634562}
\ No newline at end of file
+{"null": 4.975846767140154}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4734.json
index 9d8533085b0..796e6f23fc0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4734.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4734.json
@@ -1 +1 @@
-{"BRILIQUE": 15.56491568436153, "CLOPIDOGREL": 6.715140177953983, "ELIQUIS": 18.398287938529457, "KEYTRUDA": 2.120051534269944, "NEXAVAR": 4.913895639642781, "PLAVIX": 15.846210390817337, "SUTENT": 1.5792270786247091, "XARELTO": 15.773913364199675, "null": 1.029355015664125}
\ No newline at end of file
+{"null": 2.039075616916378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4735.json
index ba123a43123..1bc872927b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4735.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4735.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 15.071988428443808, "LONSURF": 35.05839673789991, "OLANZAPINE": 10.07359796062237, "PEGASYS": 1.9529944831177144, "null": 1.3041116346604935}
\ No newline at end of file
+{"FIRDAPSE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4736.json
index 196616c1460..95f739101d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4736.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4736.json
@@ -1 +1 @@
-{"JANUMET": 45.908988500441744, "null": 1.4049867443840058}
\ No newline at end of file
+{"COMIRNATY": 0.5048298177029752, "DEXAMETHASONE": 7.523650426104128, "FENTANYL": 4.786963044151151, "SPIKEVAX": 0.5605374326686565, "SUBOXONE": 18.150206566778685, "TOZINAMERAN": 1.3627805311937158, "null": 1.480634919980073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4737.json
index 7f10dbac858..824a8d4ab0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4737.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4737.json
@@ -1 +1 @@
-{"CIMZIA": 11.227975899318842, "ENTYVIO": 38.98175621252901, "HUMIRA": 28.132556905663627, "STELARA": 21.046049191351887}
\ No newline at end of file
+{"LEVEMIR": 41.4308938806889, "null": 1.974506303241409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4738.json
index 6c2cd661a45..05c744ea94b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4738.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4738.json
@@ -1 +1 @@
-{"BRAFTOVI": 37.64028857281047, "CELLCEPT": 6.621788692058152, "CICLOSPORIN": 2.872862349479948, "CLOPIDOGREL": 2.2214656111340023, "COSENTYX": 2.842273172174308, "ELIQUIS": 1.069592562789654, "ENTYVIO": 11.661997530901298, "GANCICLOVIR": 18.840331831147857, "HUMIRA": 4.804388682901338, "PLAVIX": 2.461264012467892, "SUTENT": 1.1504768414100526, "null": 1.7667726151685776}
\ No newline at end of file
+{"COMBIVIR": 19.24237843004301, "COMIRNATY": 0.2604609550730751, "FLUTICASONE": 111.56980245669033, "KEPPRA": 11.824963940566684, "LEVETIRACETAM": 18.912685862336, "null": 1.4693095843160748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4739.json
index 70fd19dd934..a648ff40cc3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4739.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4739.json
@@ -1 +1 @@
-{"ZOSTAVAX": 41.413996076460165, "null": 1.474794731145718}
\ No newline at end of file
+{"KEPPRA": 22.90514944777268, "null": 1.6867039320864234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/474.json
index eba6cbe9de8..446c817514a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/474.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/474.json
@@ -1 +1 @@
-{"DOXORUBICIN": 1003.0704904166596}
\ No newline at end of file
+{"null": 0.9536240008229327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4740.json
index f0f469499ca..97026e1c554 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4740.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4740.json
@@ -1 +1 @@
-{"null": 1.4912809900639403}
\ No newline at end of file
+{"null": 1.6394521558220654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4741.json
index 7ab17d62d6e..49893e3acf0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4741.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4741.json
@@ -1 +1 @@
-{"NEVIRAPINE": 118.8266648491754, "XELJANZ": 4.497342833521244, "null": 1.402212598124897}
\ No newline at end of file
+{"null": 1.3435687771524831}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4742.json
index e70fa0fae5e..ef80608db89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4742.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4742.json
@@ -1 +1 @@
-{"ALIMTA": 3.800956215802575, "AVASTIN": 43.322128058452186, "AZATHIOPRINE": 4.666936805319956, "BEVACIZUMAB": 22.42168051045469, "CABOMETYX": 9.639674328077994, "CELLCEPT": 3.4359483036397087, "CICLOSPORIN": 2.3504833974897603, "DEXAMETHASONE": 3.573436807280728, "DOCETAXEL": 4.969710625873473, "ENTYVIO": 3.0286660965271777, "IPILIMUMAB": 14.1312095025065, "KEYTRUDA": 4.593060433584121, "LENVIMA": 11.66486718706894, "NEXAVAR": 4.894418353014849, "OPDIVO": 3.873264263300012, "PLAVIX": 1.2594722195985149, "RINVOQ": 3.1395876477275526, "ROACTEMRA": 23.01936606358383, "STELARA": 2.1770731602451368, "STIVARGA": 3.2184559359953058, "SUTENT": 2.8047724397978486, "TOCILIZUMAB": 34.54522123446803, "VOTRIENT": 5.960899245118172, "XELJANZ": 1.6109863766361057, "YERVOY": 33.74146528597284}
\ No newline at end of file
+{"METHOTREXATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4743.json
index cba04000a9c..a3a363930ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4743.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4743.json
@@ -1 +1 @@
-{"BYETTA": 4.831315081878024, "CHLORMETHINE": 157.44829188806528, "CLOPIDOGREL": 1.3439565274395822, "ELIQUIS": 3.26668915874244, "ENTYVIO": 4.29907206738235, "HUMALOG": 1.4344918395650357, "HUMIRA": 1.5105529666932047, "JANUMET": 8.457163747183063, "JANUVIA": 4.495401065837074, "PANTOPRAZOLE": 12.965964232092604, "STELARA": 1.401697078596165, "VIAGRA": 2.0837684194102715, "XELJANZ": 1.089561059473435, "ZOSTAVAX": 8.159074353469759, "null": 4.937059921241006}
\ No newline at end of file
+{"COAPROVEL": 126.15602394333156, "null": 3.527931398015565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4744.json
index 112c3c1d43d..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4744.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4744.json
@@ -1 +1 @@
-{"LANTUS": 3.93473872246961, "STELARA": 9.670535321309991, "null": 1.3174520490828956}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4745.json
index eaf58561b39..1a982a67b08 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4745.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4745.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0853137950136964, "null": 2.650206510753934}
\ No newline at end of file
+{"null": 3.107957061863652}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4746.json
index bb592e52f95..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4746.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4746.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.6275636146859718, "ARAVA": 12.69420637316792, "NUCALA": 12.058114262630909, "null": 1.2026660703403305}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4747.json
index 0c6b44f1fcb..c02d3ca4726 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4747.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4747.json
@@ -1 +1 @@
-{"null": 4.587349568439264}
\ No newline at end of file
+{"COMIRNATY": 0.7234223214852681, "null": 0.636331053505638}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4748.json
index 50694133ff6..79bdaeeab97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4748.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4748.json
@@ -1 +1 @@
-{"null": 1.8059144093544437}
\ No newline at end of file
+{"null": 14.936073201685511}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4749.json
index c546f06fa8f..45eb7594259 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4749.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4749.json
@@ -1 +1 @@
-{"null": 2.356026082357269}
\ No newline at end of file
+{"COMBIVIR": 38.79745520228781, "COMIRNATY": 0.5508596658370771, "SPIKEVAX": 0.2261844908066404, "VAXZEVRIA": 0.4323084951361606, "null": 0.9216931577993224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/475.json
index a5c5fee86e1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/475.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/475.json
@@ -1 +1 @@
-{"ABATACEPT": 64.26207967972435, "ADALIMUMAB": 115.09776496810495, "APREPITANT": 18.884061263319705, "ARAVA": 2.753592127250601, "AVAMYS": 23.573254037434868, "CIMZIA": 4.464105819633202, "HUMIRA": 11.757513015983667}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4750.json
index eeb33f53380..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4750.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4750.json
@@ -1 +1 @@
-{"ELIQUIS": 18.36423744601053, "null": 1.230951775812867}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4751.json
index f1119dfb61e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4751.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4751.json
@@ -1 +1 @@
-{"COMIRNATY": 2.350955373176944}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4752.json
index 1470539c797..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4752.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4752.json
@@ -1 +1 @@
-{"null": 1.7837230327514335}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4753.json
index e06765f4b86..4abdd7ea39c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4753.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4753.json
@@ -1 +1 @@
-{"null": 1.4704209760613205}
\ No newline at end of file
+{"PAZOPANIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4754.json
index e89e1d46944..8333e9e99ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4754.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4754.json
@@ -1 +1 @@
-{"FENTANYL": 26.990544399668916, "null": 1.7826734489297238}
\ No newline at end of file
+{"COMIRNATY": 0.1635390935602642, "CYTARABINE": 29.339581089205733, "DEXAMETHASONE": 15.566931912359967, "DOXORUBICIN": 60.85012272310657, "GAZYVARO": 82.14643210998236, "LENALIDOMIDE": 144.66772577773915, "METHOTREXATE": 6.745699675844388, "OBINUTUZUMAB": 363.2573263171178, "RITUXIMAB": 39.13986195316407, "STELARA": 5.951920438689071, "null": 0.3793909836276931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4755.json
index 1ab8b0bdb8b..44334f277e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4755.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4755.json
@@ -1 +1 @@
-{"APROVEL": 2.356605175196271, "BENLYSTA": 2.2067016550619942, "BRIDION": 6.82982355841586, "BRILIQUE": 1.4620345134995587, "BUDESONIDE": 1.0647887420347122, "CAELYX": 4.306993799886247, "CINRYZE": 13.42755452938998, "COTELLIC": 3.5443050167870074, "DARZALEX": 3.805211841234778, "ENTRESTO": 1.2620027935884526, "EXFORGE": 1.8680002710767392, "FASENRA": 1.0754123124999404, "LEVOFLOXACIN": 3.267134094336276, "MICARDIS": 2.215425717480759, "MIDAZOLAM": 1.858356460073724, "ONCASPAR": 10.590741067372392, "RELVAR": 3.224186413642008, "RIXATHON": 17.021341113537023, "ROACTEMRA": 1.1551828652816236, "RUCONEST": 17.31579009665415, "XARELTO": 1.5262617888824277, "XOLAIR": 3.921325090860384, "null": 4.274417860326705}
\ No newline at end of file
+{"BYETTA": 62.100327209614754, "VICTOZA": 78.31512385967058, "null": 0.499960377561748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4756.json
index 5e7e8407737..9b472f21686 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4756.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4756.json
@@ -1 +1 @@
-{"GARDASIL": 12.417265225085814, "null": 2.249578507082471}
\ No newline at end of file
+{"ABATACEPT": 37.44384211657482, "ACETAMINOPHEN": 56.30894294731588, "ADALIMUMAB": 26.28013517982577, "AFINITOR": 0.4429651322330249, "AMINOSALICYLIC": 1.453552068393, "APREMILAST": 13.266354768790489, "APREPITANT": 67.6329721027273, "ARAVA": 13.901434437701106, "BIKTARVY": 1.9502201413583768, "BOTULINUM": 2.5482400879789493, "CELLCEPT": 0.3296982331102772, "CERTOLIZUMAB": 15.334742669003152, "CETUXIMAB": 7.631578051542689, "CHLORHEXIDINE": 87.7456234936257, "CICLOSPORIN": 0.2614124318430318, "CIMZIA": 30.643919889638155, "COMBIVIR": 1.3469811250503714, "COMIRNATY": 0.0445180557688708, "COSENTYX": 3.7974363123744497, "COTELLIC": 6.105949189442965, "EMTRICITABINE": 2.116534192884324, "ENBREL": 0.2346593923832632, "ENTYVIO": 0.8544541455596928, "GARDASIL": 0.1618769555506645, "INCIVO": 1.0403779472570422, "IRESSA": 0.8938467745233231, "KEYTRUDA": 0.1358266784960334, "MYCOPHENOLATE": 2.090261069093498, "NEXAVAR": 0.9180197973596864, "PEGASYS": 0.3430691525007698, "PEGINTRON": 0.2021210014487608, "RINVOQ": 4.532756837440648, "RITUXIMAB": 2.683598424238676, "ROACTEMRA": 1.046252309538917, "SIMPONI": 0.4840945047110964, "SPIKEVAX": 0.0443748508921443, "SPRYCEL": 0.6582690586534119, "STELARA": 0.2314182921753338, "TASIGNA": 0.9504844974438508, "TOZINAMERAN": 0.0675184027618894, "TRAMETINIB": 13.794110190105965, "VAXZEVRIA": 0.0181309858725249, "VECTIBIX": 4.164078951846105, "XELJANZ": 0.2650677798781329, "ZOSTAVAX": 0.6468512188596084, "null": 0.0898669861151704}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4757.json
index 7b0694d35fc..731a739207a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4757.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4757.json
@@ -1 +1 @@
-{"CELECOXIB": 624.8137397924909}
\ No newline at end of file
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4758.json
index 6d22a31a981..314e55022cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4758.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4758.json
@@ -1 +1 @@
-{"BUDESONIDE": 509.27007122432354}
\ No newline at end of file
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4759.json
index fac41e86cba..863491cd9ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4759.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4759.json
@@ -1 +1 @@
-{"ABATACEPT": 1.4202191278083431, "ADALIMUMAB": 5.005427635553094, "AIMOVIG": 1.0073766225266292, "ARAVA": 2.9137284949269024, "BENLYSTA": 3.319218013145508, "BOTULINUM": 9.51388159013472, "CERTOLIZUMAB": 57.180123344778046, "COSENTYX": 3.970729552398789, "HIZENTRA": 2.7231604842193677, "IBRANCE": 1.932634724051464, "LEFLUNOMIDE": 12.485960102208224, "METHOTREXATE": 1.727155827933624, "MMRVAXPRO": 3.3423246520516656, "OMALIZUMAB": 4.808069788968769, "OPSUMIT": 1.519807765905284, "PEGASYS": 1.1762761845551106, "PEGINTRON": 1.268805367589687, "ROACTEMRA": 1.8491310949772104, "SIMPONI": 2.31615460552948, "STELARA": 1.2877650080102137, "TRELEGY": 2.5631663175555377, "XELJANZ": 4.792477064733623, "XOLAIR": 2.761500365448212, "null": 1.1793629097073983}
\ No newline at end of file
+{"ROTATEQ": 66.65174812380684, "SYNAGIS": 90.0604154444893, "null": 2.08806022860263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/476.json
index fe7e0f4a8a2..14f8d5fa251 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/476.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/476.json
@@ -1 +1 @@
-{"ABACAVIR": 1.0404954006018776, "ABATACEPT": 28.10478528654915, "ACETAMINOPHEN": 43.30790007239304, "ADALIMUMAB": 50.13069383568188, "AIMOVIG": 2.0815128760090427, "AMINOSALICYLIC": 5.830572715093489, "ANAKINRA": 5.267850886950919, "APREMILAST": 33.096166370714364, "APREPITANT": 55.833767501792, "ARAVA": 37.69426586849564, "AVAMYS": 2.046979994793292, "CIMZIA": 4.017628138355303, "ERELZI": 10.1389882346431, "HUMIRA": 1.537013487242257, "MYCOPHENOLATE": 1.8600654498548703, "RITUXIMAB": 2.90581819205919}
\ No newline at end of file
+{"AUBAGIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4760.json
index 1f6f15536fc..c142b5287b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4760.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4760.json
@@ -1 +1 @@
-{"BUSULFAN": 102.8057420411659, "null": 1.1519462263089952}
\ No newline at end of file
+{"null": 1.395000896118496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4761.json
index a9f078af9f8..1f394f6aee5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4761.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4761.json
@@ -1 +1 @@
-{"DEXMEDETOMIDINE": 799.1178864668753, "null": 2.581452788607616}
\ No newline at end of file
+{"ABACAVIR": 240.7774194936877, "ABILIFY": 0.9492887520397284, "APIXABAN": 1.223119176067071, "ARAVA": 0.1126266575340205, "CICLOSPORIN": 0.4258875830356463, "CIMZIA": 0.3392184222578134, "CLOPIDOGREL": 1.834193838166688, "COMIRNATY": 0.4614286423164406, "CYMBALTA": 0.2716997699413482, "DULOXETINE": 4.947372804998524, "ENBREL": 6.069751740822659, "GARDASIL": 4.997603417966292, "HUMALOG": 0.7391834909485772, "HUMIRA": 4.6686076567887485, "INFANRIX": 6.37120734022315, "KEPPRA": 0.5817636137336641, "METFORMIN": 21.643411920315177, "METHOTREXATE": 3.5437911726769755, "MMRVAXPRO": 1.099875345181769, "OMALIZUMAB": 11.279349532479168, "ORENCIA": 59.5944235503269, "PEGASYS": 0.33605085036337, "ROTATEQ": 3.811296640628752, "SPIKEVAX": 0.3295745571578255, "STELARA": 0.7721321806503662, "TOZINAMERAN": 0.9552477398500506, "VAXZEVRIA": 0.1921224232064555, "XELJANZ": 0.5127734268222317, "XOLAIR": 4.486514102666203, "ZOSTAVAX": 0.7253773442663334, "null": 0.4723263329837441}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4762.json
index 1bd0e5fc62b..cc9f49ee78f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4762.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4762.json
@@ -1 +1 @@
-{"BRIDION": 87.2436962135678, "CAPECITABINE": 6.490139241070271, "CYTARABINE": 2.435335974190288, "DEXAMETHASONE": 2.501408092742924, "FASLODEX": 5.709147094284509, "FENTANYL": 11.347953238655776, "GLYCOPYRRONIUM": 19.779587415293364, "IRINOTECAN": 4.690793080988447, "MIDAZOLAM": 7.146323346559651, "SUFENTANIL": 9.679819183490704, "XOLAIR": 1.6510515923117082, "null": 4.358067288577303}
\ No newline at end of file
+{"CHAMPIX": 3.040702214607864, "COMIRNATY": 0.7787598451876317, "COSENTYX": 4.745409762273411, "INCIVO": 9.583655957208135, "JARDIANCE": 1.992864756929668, "KEPPRA": 2.132671859958023, "PEGASYS": 0.9705838701178054, "SAXENDA": 9.9954406755654, "SPIKEVAX": 0.3035660666892291, "SUTENT": 0.8447805973638615, "TOZINAMERAN": 0.4292796276432684, "VAXZEVRIA": 1.6941951951004728, "null": 0.7786929695520303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4763.json
index 579e97d2d58..87762c14bdf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4763.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4763.json
@@ -1 +1 @@
-{"null": 9.458141235220344}
\ No newline at end of file
+{"TOUJEO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4764.json
index 6d1a2432522..470457ee71f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4764.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4764.json
@@ -1 +1 @@
-{"null": 5.198964971256344}
\ No newline at end of file
+{"ABILIFY": 4.165696248454848, "ARIPIPRAZOLE": 12.500409241475626, "BRINTELLIX": 6.906699016369921, "CHAMPIX": 1.9396010395526244, "COMIRNATY": 0.3586383679839051, "CYMBALTA": 2.7602463590042765, "IBRANCE": 1.388947069127276, "JARDIANCE": 8.880468419720158, "OLANZAPINE": 4.019685283230825, "PEGASYS": 1.307755831606006, "SAXENDA": 67.90899668149329, "SIFROL": 28.259577915258152, "SPIKEVAX": 0.2492864966590762, "TOZINAMERAN": 0.3371587907920144, "TRULICITY": 8.09562298083101, "VAXZEVRIA": 0.444632862895343, "ZYPREXA": 7.179228382130544, "null": 0.9903163040008396}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4765.json
index 95b468fbe9d..e0f2ba68a44 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4765.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4765.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6983586387315532, "null": 2.023886935467474}
\ No newline at end of file
+{"ELIQUIS": 2.105896664224411, "KEPPRA": 2.518681754062273, "null": 3.4427334851490574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4766.json
index ca104c2a113..3f2719db4a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4766.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4766.json
@@ -1 +1 @@
-{"JARDIANCE": 22.349252911197397, "TOZINAMERAN": 2.3827473865841333}
\ No newline at end of file
+{"BOTULINUM": 19.40501386318629, "COMIRNATY": 1.0994874476621668, "COSENTYX": 1.4490410474283084, "GARDASIL": 8.632601510921315, "HUMIRA": 4.366787829941423, "IBRANCE": 1.373948620859614, "KEYTRUDA": 0.848069084878956, "PEGASYS": 1.0882138059873638, "SAXENDA": 3.9593160360086697, "SPIKEVAX": 0.4940448138376056, "SUTENT": 2.046369135692587, "TOZINAMERAN": 0.8281350251974336, "VAXZEVRIA": 0.4311234782759063, "XOLAIR": 1.857192370489176, "null": 0.949981368242166}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4767.json
index 23821a6ac53..4dc48ab7757 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4767.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4767.json
@@ -1 +1 @@
-{"BUDESONIDE": 3.7720725446389554, "CIMZIA": 9.26262196935666, "COSENTYX": 5.61445558545964, "ENBREL": 17.5118111608106, "IBUPROFEN": 13.153736572005554, "INFLIXIMAB": 38.66918822824572, "METHOTREXATE": 8.986951198342148, "SIMPONI": 9.905819472136274, "STELARA": 56.52300315935105, "TREMFYA": 22.44772158518783, "XELJANZ": 4.353631065577561}
\ No newline at end of file
+{"DEXAMETHASONE": 3.970088953212458, "HUMALOG": 3.091050951809078, "IBRANCE": 2.4288783618953502, "LANTUS": 2.303434450714469, "SAXENDA": 7.74825804228397, "SIMPONI": 3.5604538045095167, "SPIKEVAX": 0.2068000880976907, "TOZINAMERAN": 0.9446363720057124, "VAXZEVRIA": 0.1299608229778734, "XELJANZ": 3.2618134432736734, "null": 1.1342602884154642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4768.json
index 55b8677765d..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4768.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4768.json
@@ -1 +1 @@
-{"CYMBALTA": 3.0491837077550024, "LANTUS": 8.266323136106058}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4769.json
index 61ba4c2e848..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4769.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4769.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 91.58770942141544, "FENTANYL": 14.244939598272488, "GARDASIL": 2.624044532511292, "KEPPRA": 4.172058735368958, "SUBOXONE": 17.16042433368738, "null": 4.463229935315746}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/477.json
index 67cc9420c68..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/477.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/477.json
@@ -1 +1 @@
-{"ARANESP": 164.68195977219898, "PRIVIGEN": 319.5880767178647}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4770.json
index 5a71cf673fc..2af11e5d3d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4770.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4770.json
@@ -1 +1 @@
-{"GARDASIL": 2.857511896507905, "KEPPRA": 4.947956250178342, "null": 10.048640591924991}
\ No newline at end of file
+{"COMIRNATY": 0.3552259846455444, "NEXAVAR": 8.283540374489354, "SPIKEVAX": 0.6156836475924535, "TOZINAMERAN": 0.731753629321455, "VAXZEVRIA": 1.1995743828402086, "null": 1.1280456277326356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4771.json
index 306f42b6ada..bd4bdb44263 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4771.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4771.json
@@ -1 +1 @@
-{"APIXABAN": 6.734445334771607, "ARIPIPRAZOLE": 70.76812422138548, "BUMETANIDE": 462.6818693399988, "EMPAGLIFLOZIN": 159.2949034589921, "ENTRESTO": 13.847323651152758}
\ No newline at end of file
+{"INVOKANA": 567.3089878642406, "JARDIANCE": 17.526428997293525, "LANTUS": 32.16234642593302, "null": 0.3171985300204046}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4772.json
index a6b151d895a..b3c3e37f2b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4772.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4772.json
@@ -1 +1 @@
-{"AVANDIA": 11.297753703386013, "ENTRESTO": 30.113201636170395, "null": 1.412189553736513}
\ No newline at end of file
+{"ABATACEPT": 11.851920354377272, "ADALIMUMAB": 11.478885576691944, "AERIUS": 5.586170639255544, "ANAKINRA": 15.941327594748644, "ARAVA": 13.215359574165369, "AVAMYS": 1.6423447416896308, "CELECOXIB": 3.4266784750706885, "CIMZIA": 1.51244655022368, "COMBIVIR": 5.03464370043909, "COMIRNATY": 0.075063168497255, "CYMBALTA": 0.6638284096754097, "ELIQUIS": 0.2828018310643533, "ENBREL": 8.968887827127846, "EVISTA": 2.9630271492477087, "FORSTEO": 1.0471031704348108, "GARDASIL": 1.4301664729961687, "HUMALOG": 1.4961543902764485, "HUMIRA": 4.43579835225708, "KEPPRA": 0.8892918304873634, "LANTUS": 0.5597002805977078, "LEFLUNOMIDE": 13.959623179902268, "LEVETIRACETAM": 1.2071344007631064, "LYRICA": 1.6915265196538756, "METHOTREXATE": 3.601113045777461, "RINVOQ": 2.102469250205938, "RITUXIMAB": 1.77597207196156, "SIMPONI": 3.2204537318002884, "SPIKEVAX": 0.0629624028332113, "TOZINAMERAN": 0.0865516798000676, "VAXZEVRIA": 0.0463464207624901, "XELJANZ": 7.956546115312522, "ZOSTAVAX": 2.3035159453035607, "null": 0.8717530383522546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4773.json
index 837c4d57c15..43c13970e13 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4773.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4773.json
@@ -1 +1 @@
-{"null": 3.859667713920546}
\ No newline at end of file
+{"ADALIMUMAB": 0.0708741597021958, "AIMOVIG": 0.546841754661814, "APIDRA": 2.231101418993607, "ARANESP": 0.4644401589274713, "ARAVA": 0.957972522155242, "ATRIPLA": 26.79023749201191, "AUBAGIO": 1.141973266192424, "AVANDIA": 1.5093916744293256, "BENLYSTA": 0.7246862416900939, "BONVIVA": 2.9904376969671675, "BYETTA": 0.8327756139861298, "CIMZIA": 0.4256962540078852, "COMIRNATY": 0.0215293722100759, "COSENTYX": 0.2688682974831967, "CYMBALTA": 0.4467089837232596, "DACLATASVIR": 6.381036602960899, "DARUNAVIR": 3.746935734761056, "ELIQUIS": 0.8889790954327549, "ENBREL": 0.6498980821290247, "ENTYVIO": 0.8634465268919164, "EVENITY": 3.732413956682307, "EVISTA": 4.795124752268973, "EXFORGE": 0.9745636033353892, "FAMPYRA": 1.1858017345985088, "FIRDAPSE": 2.887743426747204, "FORSTEO": 2.3599087106467174, "HEPSERA": 5.8403118744172975, "HUMALOG": 2.203023074616803, "HUMIRA": 0.5683200622950434, "IBRANCE": 0.8032873607108121, "ILARIS": 64.11176941463039, "INSULIN": 0.6290919182985825, "JANUMET": 0.9170516160099712, "JANUVIA": 0.452132751547091, "KALETRA": 2.928405600536122, "KEPPRA": 0.7469359111037774, "LANTUS": 2.6964894633586383, "LEFLUNOMIDE": 2.9140784471922734, "LEVEMIR": 1.4228691992418347, "LYRICA": 2.261441528886728, "MEPOLIZUMAB": 0.6435211177868219, "METHOTREXATE": 0.718005749412024, "MICARDIS": 1.108622760942186, "OMALIZUMAB": 1.2697625881499408, "OPSUMIT": 0.8037925017493252, "REVATIO": 1.3311348512614416, "RITUXIMAB": 2.314853786206414, "SAXENDA": 1.0544730541532448, "SIMPONI": 1.6017691254445114, "SPIKEVAX": 0.0302620844987635, "SPINRAZA": 2.061476419417024, "STELARA": 0.5757780353608548, "STRIBILD": 13.093899613779907, "SUBOXONE": 2.93222341937481, "SUTENT": 0.1088635205448529, "TOZINAMERAN": 0.0661071343934292, "TREMFYA": 1.3130754531084758, "TRUVADA": 19.006097479218766, "VAXZEVRIA": 0.0152841940501149, "VIAGRA": 1.152084746963875, "VIREAD": 8.63491394805124, "XELJANZ": 3.35175163406755, "XOLAIR": 1.0151239425751, "XTANDI": 0.4540771744626995, "XYREM": 2.2089337026026463, "ZOSTAVAX": 1.4786176850137769, "ZYPREXA": 0.2568463378218732, "null": 0.5624304101035531}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4774.json
index a4101037bb3..e6c04fe2447 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4774.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4774.json
@@ -1 +1 @@
-{"BUMETANIDE": 312.61300321709945, "ENTRESTO": 26.345040155626634, "IRBESARTAN": 32.987062152563816, "null": 1.2717564125495646}
\ No newline at end of file
+{"ABATACEPT": 6.44035047144176, "ACETYLSALICYLIC": 349.00448361854524, "ADALIMUMAB": 8.577991729237564, "ANAKINRA": 16.659282535172903, "ARAVA": 7.043362194191314, "AUBAGIO": 2.9381704622259286, "CIMZIA": 3.350374282246914, "LANTUS": 8.161798943910071, "RINVOQ": 5.343728108083647, "SIMPONI": 18.29962574799945, "STELARA": 2.111106358042389, "XELJANZ": 7.889994784542765, "ZOSTAVAX": 2.377185911944788, "null": 0.6268678636617413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4775.json
index c47e0c80ca6..647a79c3cd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4775.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4775.json
@@ -1 +1 @@
-{"ABILIFY": 5.33035179267404, "ALIMTA": 2.708297761606201, "ARIPIPRAZOLE": 16.875062162135812, "AVANDAMET": 5.097039210258387, "AVANDIA": 6.683133943722663, "AVASTIN": 3.7269477565575433, "BEVACIZUMAB": 6.381683760872453, "BRILIQUE": 2.260032367703613, "CAPECITABINE": 5.894981229938773, "CELLCEPT": 2.131584345210736, "CICLOSPORIN": 1.3393456171396518, "CLOPIDOGREL": 4.395230166769288, "CYTARABINE": 1.8835761924312624, "DOCETAXEL": 12.845707313435303, "DOXORUBICIN": 3.170162348835011, "EDOXABAN": 68.52043206096512, "ENTRESTO": 16.764707657584573, "FENTANYL": 1.5399770132745128, "GEFITINIB": 13.46179432791123, "HERCEPTIN": 15.078983352772816, "KYMRIAH": 6.337394284218184, "KYPROLIS": 6.130115922622025, "MEKINIST": 2.192436164083205, "MIDAZOLAM": 8.197942745723498, "NEXAVAR": 1.929065321048978, "OLANZAPINE": 1.3708979528349223, "PERTUZUMAB": 37.70973436625419, "RITUXIMAB": 1.8750071705884572, "SPIRONOLACTONE": 7.442164055802391, "STIVARGA": 1.4858772384252443, "SUTENT": 1.0671112300149257, "TASIGNA": 2.668084826914534, "VALSARTAN": 8.835973442662553, "VOTRIENT": 3.168735737032114, "null": 1.1365036879081427}
\ No newline at end of file
+{"AERIUS": 2992.9661323418613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4776.json
index efeba47cb9b..624df2a6ada 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4776.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4776.json
@@ -1 +1 @@
-{"null": 1.4178238387485211}
\ No newline at end of file
+{"VFEND": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4777.json
index 23fedf439d4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4777.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4777.json
@@ -1 +1 @@
-{"ENTRESTO": 67.98384027123443, "null": 1.0910326714775302}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4778.json
index 84a89b005c1..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4778.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4778.json
@@ -1 +1 @@
-{"ADCIRCA": 14.08996904100706, "AVANDIA": 6.345851504312924, "BUSULFAN": 5.956514453682168, "DASATINIB": 26.891434496853503, "ELIQUIS": 1.6917117816593152, "ENTRESTO": 3.863290671981001, "MULTAQ": 10.09203072065948, "NEXAVAR": 1.1880630161458223, "ONGLYZA": 70.64423012632452, "OPSUMIT": 12.504269814102663, "REVATIO": 10.348056324913514, "SUTENT": 1.7852504844048247, "TRACLEER": 10.338111683798267, "ZOSTAVAX": 1.2714370314060206, "null": 1.504195486686657}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4779.json
index d09a0bfd327..0b808b9240b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4779.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4779.json
@@ -1 +1 @@
-{"ACTOS": 14.494051311241712, "AMINOSALICYLIC": 2.828867267371061, "AVANDIA": 7.09938559562857, "AZATHIOPRINE": 3.47999432521569, "BEDAQUILINE": 5.751340668676269, "CLOPIDOGREL": 2.5233553145116003, "ENTRESTO": 6.928718050347364, "INSULIN": 2.7795099109884123, "JANUMET": 2.7647809072996967, "LEVETIRACETAM": 2.6927629518092417, "MICARDIS": 5.381877839465967, "MIDAZOLAM": 4.096070028400209, "OLANZAPINE": 1.5044104279230517, "OPTIMARK": 3.5895976354178023, "PEGINTRON": 1.1972866365520043, "SILDENAFIL": 6.765230377894711, "TASIGNA": 6.120326506146673, "TELMISARTAN": 12.13198423660111, "TESTOSTERONE": 46.62225786585368, "VALSARTAN": 21.03672978620776, "ZOSTAVAX": 5.63642101762027, "ZYPREXA": 5.813500893793271, "null": 1.6919932119694607}
\ No newline at end of file
+{"TELMISARTAN": 2804.388150094649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/478.json
index c6ead1e1f42..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/478.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/478.json
@@ -1 +1 @@
-{"PRIVIGEN": 730.083056576617}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4780.json
index 58b115cf274..09625d32d70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4780.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4780.json
@@ -1 +1 @@
-{"RIOCIGUAT": 20394.860412082395, "SILDENAFIL": 391.0388391056505}
\ No newline at end of file
+{"null": 1.5345798162876387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4781.json
index 23108efb937..73c8ed9a0ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4781.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4781.json
@@ -1 +1 @@
-{"APIDRA": 4.660726542374589, "AVANDIA": 4.68164557239068, "FORXIGA": 6.286919909786217, "HUMALOG": 5.516518080632216, "HUMIRA": 3.4564480786839056, "INSULIN": 5.442274200635206, "INVOKANA": 213.12920258511377, "JARDIANCE": 16.604985945736537, "LANTUS": 25.484349441692498, "LEVEMIR": 17.19800812639043, "OPTIMARK": 4.503459517076035, "PLAVIX": 1.2464496064440231, "SIMPONI": 1.6133151928136444, "STELARA": 1.572159393246871, "VELTASSA": 19.24300274765625}
\ No newline at end of file
+{"AVAMYS": 176.6124145195051, "ESOMEPRAZOLE": 153.72221324368624, "MEPOLIZUMAB": 53.08499381938294, "null": 0.3085273525936356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4782.json
index f41c56971b8..a32af9c2ddb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4782.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4782.json
@@ -1 +1 @@
-{"null": 1.3676015331365603}
\ No newline at end of file
+{"ANORO": 131.2388577090135, "APIXABAN": 42.578949522765285, "AVAMYS": 29.03288737448556, "AZATHIOPRINE": 19.318378697585, "BUDESONIDE": 4.435310806827292, "CICLOSPORIN": 1.6383233010001357, "FASENRA": 14.013334315191551, "KAFTRIO": 40.28055751195593, "KALYDECO": 39.84352076104096, "MEPOLIZUMAB": 5.019148900134135, "NUCALA": 10.258847266428669, "OMALIZUMAB": 158.1560419604483, "ORKAMBI": 210.98520079574155, "TOBI": 189.36367883747508, "XOLAIR": 29.310949396213665, "null": 0.2730186728515671}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4783.json
index cf45cd4d1c6..343b32387da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4783.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4783.json
@@ -1 +1 @@
-{"CICLOSPORIN": 17.36339163904472}
\ No newline at end of file
+{"NUCALA": 101.01952374079964, "VAXZEVRIA": 1.449764843599997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4784.json
index 2c49a215978..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4784.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4784.json
@@ -1 +1 @@
-{"null": 1.1993519194026288}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4785.json
index 36774ca2c8b..0ec754b9cac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4785.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4785.json
@@ -1 +1 @@
-{"PAZOPANIB": 233.90928402187205}
\ No newline at end of file
+{"OMALIZUMAB": 287.46289209490635}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4786.json
index 692baf07437..a3dad20fbd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4786.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4786.json
@@ -1 +1 @@
-{"VOTRIENT": 128.5271986993595}
\ No newline at end of file
+{"BUDESONIDE": 10.341640257267889, "ESBRIET": 65.93658430880326, "FLUTICASONE": 277.28250946491227, "NUCALA": 33.53279246580824, "OFEV": 89.14292732257697, "OMALIZUMAB": 45.85813625126464, "PIRFENIDONE": 405.76837801449045, "TELMISARTAN": 311.63286284412646, "null": 0.1586449494360388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4787.json
index a64a989cffb..49331912cd4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4787.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4787.json
@@ -1 +1 @@
-{"null": 1.550517434167808}
\ No newline at end of file
+{"OFEV": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4788.json
index 130b2b3da69..04076fe4925 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4788.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4788.json
@@ -1 +1 @@
-{"ASPARAGINASE": 252.46334778932453, "BOTULINUM": 195.5232187538583, "KEPPRA": 39.79996604871586}
\ No newline at end of file
+{"ATRIPLA": 15.18377083368827, "TRUVADA": 12.351142054677586, "null": 0.3111600275763773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4789.json
index 5ff1344354e..15322d9bbcf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4789.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4789.json
@@ -1 +1 @@
-{"null": 1.46416688640993}
\ No newline at end of file
+{"ELIQUIS": 6.730289623888353, "LANTUS": 10.112010268024688, "null": 1.2578664551525562}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/479.json
index 21de16e0c12..30380b6ee3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/479.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/479.json
@@ -1 +1 @@
-{"ARANESP": 63.4887630842544, "null": 2.8918101261397577}
\ No newline at end of file
+{"null": 1.719128601799418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4790.json
index ef3402337ed..e71d3f55fcb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4790.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4790.json
@@ -1 +1 @@
-{"null": 1.733021882012422}
\ No newline at end of file
+{"null": 5.660026639471274}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4791.json
index 878d7a8d70f..88ed3e6917b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4791.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4791.json
@@ -1 +1 @@
-{"BRAFTOVI": 78.7446942258701, "COSENTYX": 44.756918601738896, "VFEND": 48.173506867500194}
\ No newline at end of file
+{"HUMIRA": 622.1465906276263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4792.json
index 65c1ca081dd..a28046288cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4792.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4792.json
@@ -1 +1 @@
-{"CIALIS": 1389.5915893463423, "VIAGRA": 177.21213866619368}
\ No newline at end of file
+{"EYLEA": 88.505671666285, "null": 1.558357025504113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4793.json
index 29d751894b0..8cd970729ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4793.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4793.json
@@ -1 +1 @@
-{"LAMIVUDINE": 201.357822559237, "null": 1.695933139054759}
\ No newline at end of file
+{"null": 3.1100755720052486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4794.json
index 352abcf2d6a..bac6db672b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4794.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4794.json
@@ -1 +1 @@
-{"ASPARAGINASE": 629.9935959036418}
\ No newline at end of file
+{"null": 9.241648297161886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4795.json
index e1fdd58c7bb..9eb28f4dee6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4795.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4795.json
@@ -1 +1 @@
-{"CICLOSPORIN": 33.332111642137754}
\ No newline at end of file
+{"HUMIRA": 35.59934875473306, "null": 2.960407296740769}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4796.json
index b5713e4621d..93ec4851ab7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4796.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4796.json
@@ -1 +1 @@
-{"ADEMPAS": 1.2489347825872583, "ASPARAGINASE": 1.0146194655975578, "AZILECT": 1.9361525551742127, "BEXSERO": 4.853299975916843, "BUMETANIDE": 3.227079935636893, "BUPIVACAINE": 2.432726387351796, "CANNABIDIOL": 4.37397642326073, "CASPOFUNGIN": 1.641417808187857, "CHAMPIX": 1.6365640181779608, "COMIRNATY": 1.345748745408761, "COVID19": 3.247695603471658, "CRIXIVAN": 1.2023407872613594, "CYMBALTA": 6.885095420511219, "DARATUMUMAB": 5.012191801092992, "DASATINIB": 1.759573185269558, "DELAMANID": 2.526978350067973, "EMPAGLIFLOZIN": 1.7492003885500913, "ENTRESTO": 1.0634708487389448, "FIRDAPSE": 1.633589429367823, "FOTIVDA": 2.8195867854336782, "FYCOMPA": 1.0773824714737297, "GALAFOLD": 1.8107797015881395, "GARDASIL": 1.6071870697019528, "HYDROCORTISONE": 1.5955587072094752, "IBUPROFEN": 1.182180120293513, "IMATINIB": 1.818450338566282, "INCIVO": 1.5462911951117086, "INFANRIX": 3.595380299708533, "INTERFERON": 3.350577336109295, "IRON": 1.7144388710528022, "KEPPRA": 1.6615607481519337, "MELATONIN": 1.2999173270718194, "MEMANTINE": 2.304281742699432, "MULTAQ": 1.138406141774161, "NIMENRIX": 1.970609414046216, "OLANZAPINE": 1.4883010686217863, "ORENCIA": 2.4940697925235287, "OXYBUTYNIN": 1.5522422876977415, "PEGINTERFERON": 1.590463474064481, "PREVENAR": 1.7847414857724646, "PROPRANOLOL": 1.0551694666124307, "RANEXA": 1.3446069553506803, "RISPERIDONE": 7.957249694101176, "ROTARIX": 5.092917150057466, "ROTATEQ": 5.142984259217696, "SUBOXONE": 1.2601302021828251, "TEDUGLUTIDE": 5.601716806197969, "TOPOTECAN": 1.172465362303751, "TOZINAMERAN": 2.997497318288075, "VIMPAT": 1.1725200867694852, "XTANDI": 1.280372847363651, "XYREM": 3.511171568626322, "ZYPADHERA": 1.4443290526086083, "ZYPREXA": 1.2606588846802216}
\ No newline at end of file
+{"BRAFTOVI": 6.902869377386941, "COMIRNATY": 0.098999627240583, "COMTAN": 14.564890833762073, "IBRANCE": 5.244334363673514, "RELVAR": 22.68240933183316, "TOZINAMERAN": 0.3855763309035044, "TRELEGY": 33.03383072148257, "XTANDI": 23.56750391630196, "null": 4.208809127853953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4797.json
index 7becd721447..f3d9ac3b98a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4797.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4797.json
@@ -1 +1 @@
-{"null": 12.220140829168235}
\ No newline at end of file
+{"null": 1.7303640841198316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4798.json
index a81b0114c22..c1384db15a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4798.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4798.json
@@ -1 +1 @@
-{"null": 2.6556073102073143}
\ No newline at end of file
+{"FENTANYL": 49.76434945181951, "null": 1.294615628706115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4799.json
index 755d7f0e8d5..627a678ccac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4799.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4799.json
@@ -1 +1 @@
-{"ABILIFY": 32.42495844778806, "ARIPIPRAZOLE": 29.141245774450045, "ASPARAGINASE": 3.2715742746403347, "BOSULIF": 3.4997137297925662, "BUSULFAN": 3.096675511503505, "CHLORMETHINE": 78.27003535870135, "CRESEMBA": 15.208481165981857, "CYTARABINE": 3.5443285638424578, "DEXAMETHASONE": 1.0559283557727368, "DOXORUBICIN": 3.910483703794333, "ELIQUIS": 1.91196511270351, "EXJADE": 14.559671672923406, "FORSTEO": 2.091603351736853, "HUMALOG": 1.8432198070596224, "JAKAVI": 14.991140403365906, "KEPPRA": 1.5611326785353723, "LANTUS": 2.1767884414228598, "LEVEMIR": 1.764340245604688, "LYNPARZA": 7.248800798708685, "METHOTREXATE": 1.213340472005929, "NEULASTA": 2.069665565522324, "NOXAFIL": 21.38399227889401, "NPLATE": 5.240278610971806, "PLAVIX": 1.1180453826933252, "SIMPONI": 1.625565115489751, "SOLIRIS": 1.957402662970405, "SPRYCEL": 9.611546395556612, "STELARA": 2.1177966329264737, "TASIGNA": 2.1325683615721696, "VFEND": 30.19362380106578, "VIAGRA": 1.8045259152077688, "XELJANZ": 1.2592353269887553, "XOLAIR": 1.9374177765361331, "null": 1.2166350230261036}
\ No newline at end of file
+{"BEOVU": 26.226150408941898, "COMIRNATY": 0.4165277698023021, "EYLEA": 43.32788307392756, "NEPAFENAC": 629.2321277083585, "NEVANAC": 270.04463671168526, "OMALIZUMAB": 5.035269928678844, "SPIKEVAX": 0.2296756535985381, "TOZINAMERAN": 0.8397822290354364, "VAXZEVRIA": 0.4522380702016037, "ZOSTAVAX": 2.1562463133456067, "null": 1.725172363378974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/48.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/48.json
index 6f3fef90945..3522a73568a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/48.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/48.json
@@ -1 +1 @@
-{"COMIRNATY": 1.314762255279745}
\ No newline at end of file
+{"ARIXTRA": 70.51519536618059, "CLOPIDOGREL": 10.104299292350154, "ELIQUIS": 7.290085562780676, "ENOXAPARIN": 135.3112663266006, "INHIXA": 81.90071154690648, "PLAVIX": 6.2889205596248825, "XARELTO": 19.39152434148882, "null": 4.088024746732292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/480.json
index 7856708f3ec..b1a15f0b856 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/480.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/480.json
@@ -1 +1 @@
-{"ARANESP": 92.8942963410077, "CELLCEPT": 12.329698044569628, "EPOETIN": 675.2947513744114, "MYCOPHENOLATE": 62.32364709530312, "null": 2.0206059268522774}
\ No newline at end of file
+{"ABILIFY": 1.8981675168423169, "ACTOS": 6.028416208279905, "ACTRAPID": 1.5519825369524305, "ADALIMUMAB": 0.2165613588138942, "AFINITOR": 0.3418996890649842, "ALEMTUZUMAB": 0.4229874746243265, "ALOXI": 6.640526091070373, "AMINOSALICYLIC": 0.8773240177208977, "APIDRA": 2.3255643928279883, "APIXABAN": 0.1868367466823111, "ARIPIPRAZOLE": 1.582164664765567, "ASPARAGINASE": 2.185810600706365, "AVASTIN": 1.5752878860292814, "AZATHIOPRINE": 0.3351038347650187, "AZILECT": 2.5745269417249164, "BENZODIAZEPINE": 3.078522396003399, "BEVACIZUMAB": 0.7436109918996117, "BONVIVA": 1.1610603207200658, "BRIDION": 0.9741614253703318, "BRINTELLIX": 0.3338406193934425, "BUPIVACAINE": 0.672259876706317, "BUPRENORPHINE": 1.5675172683152, "BUSULFAN": 0.6956412560468809, "CABOMETYX": 0.4981227191106614, "CANCIDAS": 2.175993581873835, "CELECOXIB": 0.7749465091619787, "CELLCEPT": 0.5788876722978905, "CHAMPIX": 1.761351052919007, "CICLOSPORIN": 1.651876492066667, "CLOPIDOGREL": 0.8680815760725549, "COAPROVEL": 2.5894141406469458, "COMIRNATY": 0.3724808981114291, "CYMBALTA": 1.0632723769917325, "CYTARABINE": 0.2927481210316298, "DAPAGLIFLOZIN": 2.625296757176017, "DAPTOMYCIN": 5.509876812962887, "DEFITELIO": 5.130072330182727, "DELAMANID": 1.4974066970623123, "DESCOVY": 3.1681226227730144, "DEXAMETHASONE": 0.7290306143741575, "DOCETAXEL": 0.392212270341843, "DOXORUBICIN": 0.8290592900660536, "DULOXETINE": 2.650652268560339, "EBIXA": 2.9400648935380524, "ELIQUIS": 0.2567172809198012, "ENTRESTO": 0.2099545000393154, "EPIVIR": 0.9897101045661963, "EVENITY": 1.1548102304197618, "EXJADE": 0.2781863487933741, "FENTANYL": 1.6167290034288169, "FORXIGA": 1.6775811201928286, "FYCOMPA": 5.8775045454376045, "GARDASIL": 0.7165226724060441, "GLIBENCLAMIDE": 8.079651360125947, "GLUCAGON": 3.375257157275059, "HARVONI": 0.4865319364361621, "HUMALOG": 0.9906817352614894, "HYDROCORTISONE": 0.5459387244293418, "IBUPROFEN": 0.3455754166462362, "INLYTA": 0.6184884869320434, "INSULIN": 2.912913779201449, "INTRONA": 2.092654666118045, "IRBESARTAN": 0.97167292764996, "IRESSA": 0.9607796914142396, "IRINOTECAN": 0.6199986327695366, "JAKAVI": 0.8347261723370707, "JANUVIA": 1.755597070023312, "JARDIANCE": 2.87706179882228, "JEVTANA": 2.2973471479308376, "KALETRA": 1.183723651082191, "KEPPRA": 1.0504932990759457, "KEYTRUDA": 1.2756894600227198, "KYMRIAH": 0.91646712165303, "LACOSAMIDE": 0.8375715354555232, "LANTUS": 1.4695105607320338, "LATUDA": 0.75157828211637, "LENVIMA": 2.4799665845552, "LEVEMIR": 0.4671310472772778, "LEVETIRACETAM": 2.281512622524628, "LEVODOPA": 1.6441949671953469, "LEVOFLOXACIN": 1.2083738547575174, "LOXAPINE": 7.47240532226129, "LYRICA": 3.527660835278154, "MANNITOL": 5.262091304159024, "MEKINIST": 1.1326494482209235, "MEMANTINE": 2.7660166607834733, "METFORMIN": 6.941119395343088, "METHOTREXATE": 0.2787003141718709, "MICARDIS": 1.60124032733442, "MIDAZOLAM": 4.247092809747, "MIRABEGRON": 5.39633365741133, "MMRVAXPRO": 0.3684368411837619, "MYCOPHENOLATE": 0.5844424328627399, "NALOXONE": 4.9580686514756165, "NEXAVAR": 1.256886314339779, "NOT": 0.8409482381978342, "NOVORAPID": 1.105833661887288, "OLANZAPINE": 3.410629123317774, "OPDIVO": 1.5461031180201497, "OPSUMIT": 0.2695919565929374, "PALIPERIDONE": 5.854295983308866, "PEGASYS": 0.1599547392534382, "PEGINTERFERON": 0.5424218949073734, "PEGINTRON": 0.6610962885724861, "PERAMPANEL": 12.23001555370216, "PLAVIX": 0.6676059542885753, "PRADAXA": 1.6151779508760369, "PREGABALIN": 3.466503339746278, "PROPRANOLOL": 3.216831849858869, "RASILEZ": 1.263480041970794, "REPAGLINIDE": 5.84545652419119, "RIBAVIRIN": 0.6852771228308678, "RINVOQ": 0.3788586811741142, "RISPERIDONE": 1.548466174506333, "ROTARIX": 8.57877698802745, "SAMSCA": 11.7634952913407, "SHINGRIX": 0.1686961589792723, "SIFROL": 1.9401593814837224, "SIMPONI": 0.116969857782746, "SOLIRIS": 0.2712747270276545, "SOVALDI": 2.024050394367631, "SPIKEVAX": 0.2579375331099423, "STIVARGA": 1.4832405774262365, "SUBOXONE": 0.2368794690752421, "SUTENT": 0.4017723120507661, "TAGRISSO": 0.5655089985582478, "TAMIFLU": 9.507906163289748, "TELMISARTAN": 1.9644446446622763, "TOZINAMERAN": 0.1275567003795089, "TWINRIX": 0.5803626775388532, "VAXZEVRIA": 0.0948777823893305, "VECTIBIX": 1.896955946767681, "VELCADE": 4.04357212866022, "VFEND": 5.169284655202852, "VIAGRA": 0.3193132680740744, "VIMPAT": 2.4306724795353998, "VORICONAZOLE": 2.107890333258095, "XARELTO": 0.7940269332529248, "XOLAIR": 0.1353599189908437, "XTANDI": 0.2935043616663018, "YESCARTA": 0.6696333816495911, "ZONISAMIDE": 4.500602372188896, "ZYPADHERA": 6.098538538996962, "ZYPREXA": 3.4411979518512434, "null": 2.9402900668988816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4800.json
index cd6eb900f7e..00eb018abf8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4800.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4800.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 22.67287098012612, "ARSENIC": 1480.678075625734, "ASPARAGINASE": 39.38746816765458, "BLINATUMOMAB": 98.04356151587376, "BUSILVEX": 121.42520941204472, "BUSULFAN": 70.90840328640249, "CASPOFUNGIN": 36.85167843717864, "CICLOSPORIN": 20.49041436516287, "CLOFARABINE": 77.08779789168332, "CYTARABINE": 28.267523141071106, "EXJADE": 4.742938287362217, "ICLUSIG": 31.68209624846668, "KYMRIAH": 10.81243580264405, "MERCAPTOPURINE": 32.29158903987639, "METHOTREXATE": 9.15323382639019, "NOXAFIL": 24.593829632849364, "SPRYCEL": 11.621405669090858, "TASIGNA": 16.504493091168484, "VFEND": 21.148782131931178}
\ No newline at end of file
+{"ABILIFY": 0.7673139373626675, "AUBAGIO": 0.8400103292807596, "BRINTELLIX": 2.7840778297103115, "BUPIVACAINE": 3.842590564027162, "CHAMPIX": 1.3306227832359174, "COMIRNATY": 1.6395352669216237, "CYMBALTA": 1.68823706271685, "ELIQUIS": 0.2547755242234803, "FENTANYL": 0.67002003446945, "FORSTEO": 1.4700662862279257, "GARDASIL": 1.135900346463136, "KEPPRA": 0.4295359992559721, "LANTUS": 0.9642803931065064, "LYRICA": 1.0254577586327251, "MODERNA": 4.293332193948601, "PEGASYS": 0.8583816480347872, "SHINGRIX": 0.7612052410071267, "SIMPONI": 1.038068129483576, "SPIKEVAX": 0.7411477120727696, "STELARA": 0.5896440331488514, "SUBOXONE": 2.8235380024702352, "TOZINAMERAN": 0.8847756611319684, "TWINRIX": 7.460690967269573, "VAXZEVRIA": 1.0669189362239218, "XELODA": 4.762352058622428, "ZYPREXA": 0.7570916568501918, "null": 1.4401206695298794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4801.json
index da5d25c785b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4801.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4801.json
@@ -1 +1 @@
-{"null": 2.287399874957282}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4802.json
index f6769da3d9c..6f284eaa726 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4802.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4802.json
@@ -1 +1 @@
-{"OLANZAPINE": 549.0021310917658}
\ No newline at end of file
+{"ASPARAGINASE": 3.75999569342926, "AVASTIN": 4.566646751941444, "BEVACIZUMAB": 5.995825775030709, "EMPAGLIFLOZIN": 113.05436512855135, "FORXIGA": 77.28684335655478, "INVOKANA": 29.700321249119792, "JARDIANCE": 527.3962475357285, "ROACTEMRA": 2.513416677689425, "SUTENT": 0.6491255716032818, "null": 0.0765742717181008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4803.json
index 914cb40f26f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4803.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4803.json
@@ -1 +1 @@
-{"null": 4.300975156186353}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4804.json
index 97b1c56c4e5..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4804.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4804.json
@@ -1 +1 @@
-{"AMIKACIN": 3.0157308620725773, "ARIPIPRAZOLE": 5.213339869676421, "ATAZANAVIR": 1.1687295354980527, "AVASTIN": 1.3104780209875737, "AZACITIDINE": 3.7453140505611313, "BETAFERON": 1.7105813310319662, "BYDUREON": 1.4323281080928656, "BYETTA": 2.449650134349874, "CANNABIDIOL": 5.210673312692011, "CELLCEPT": 1.1421481632969177, "CICLOSPORIN": 2.2306462037658674, "COMTAN": 3.353441305859976, "CUBICIN": 1.7665851113983135, "CYTARABINE": 2.2877321042925938, "DASATINIB": 12.145605580698366, "DEXAMETHASONE": 2.6152985389337187, "DOCETAXEL": 1.154325978187353, "DOLUTEGRAVIR": 6.986331431046132, "DULOXETINE": 1.12895151270939, "ENOXAPARIN": 1.235807061618023, "EXJADE": 4.307885996779434, "EXVIERA": 4.379126736334502, "FILGRASTIM": 8.284765185677102, "FIRDAPSE": 3.2988755388621627, "IBUPROFEN": 2.556335006828665, "ICLUSIG": 5.77165108887904, "INVOKANA": 6.739419834490064, "IRBESARTAN": 2.4007062342222567, "IRINOTECAN": 1.5904766899644731, "ISENTRESS": 2.2313904262082334, "JAKAVI": 11.868743467460938, "JANUMET": 2.988494567055332, "JANUVIA": 3.26894626282866, "JEVTANA": 1.9307509558663836, "LEMTRADA": 1.498257210336745, "LEVETIRACETAM": 2.018622219861783, "LEVOFLOXACIN": 3.2606389958573483, "LONSURF": 2.549562938245106, "MIDAZOLAM": 2.728538967873844, "NEULASTA": 22.88526447382734, "NILOTINIB": 4.618693393519429, "NPLATE": 10.095916600891856, "OLANZAPINE": 4.959125689385736, "OLYSIO": 1.9461588832872252, "PANTOPRAZOLE": 1.8211836538599648, "PEGFILGRASTIM": 11.068767733409931, "RISPERIDONE": 3.5071704222147417, "ROTATEQ": 1.2160750620135483, "RUXOLITINIB": 21.679110582355044, "SOLIRIS": 1.1814973254307295, "SPRYCEL": 1.7105179773334331, "TASIGNA": 4.133510356755458, "TOBRAMYCIN": 5.886981850906022, "TRISENOX": 16.82479904356629, "VENETOCLAX": 3.435863819164556, "ZOSTAVAX": 1.1497030368508947, "ZYPREXA": 2.9899729898801004, "null": 2.1871848229354702}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4805.json
index c85bfcf4e96..9640c1ca863 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4805.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4805.json
@@ -1 +1 @@
-{"JARDIANCE": 11.060299917517954, "null": 1.2607784966970002}
\ No newline at end of file
+{"CHOLESTAGEL": 13346.819653084816, "null": 0.5623079634166885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4806.json
index e77ae940751..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4806.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4806.json
@@ -1 +1 @@
-{"KEYTRUDA": 25.213205145039304, "OPDIVO": 230.95446120214768}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4807.json
index 4e21f5f4a85..0544b198867 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4807.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4807.json
@@ -1 +1 @@
-{"GARDASIL": 132.95789170707545}
\ No newline at end of file
+{"ABILIFY": 0.3930647505941536, "AFINITOR": 0.2503317692756261, "ARAVA": 0.3384547546906315, "ATRIPLA": 25.288779362352965, "AVANDIA": 2.406422488438323, "BENLYSTA": 0.5184240967096201, "BONVIVA": 6.166452749831576, "CABOMETYX": 0.7404768847178874, "CHAMPIX": 0.73264100201832, "CIMZIA": 0.5483674716405201, "COMIRNATY": 0.0435729098745139, "COMTAN": 1.737320038930249, "COSENTYX": 0.2412645806865352, "CYMBALTA": 0.2582007296736726, "DARZALEX": 0.8294599110702771, "ELIQUIS": 0.9872679774120948, "EVENITY": 110.43387424951868, "EVISTA": 15.021470351922598, "EXFORGE": 0.5569478582954425, "EXJADE": 0.5416680574089467, "FASLODEX": 1.6396151819144398, "FESOTERODINE": 14.77680835255884, "FORSTEO": 3.5924614077263577, "FULVESTRANT": 1.232645819864864, "HEPSERA": 10.55615778216707, "HUMALOG": 0.3012840263276843, "IBRANCE": 0.9713720356557546, "INLYTA": 0.5468208148913889, "JAKAVI": 1.001779714977452, "JANUVIA": 0.327360335922309, "JARDIANCE": 0.1642169656491077, "KALETRA": 11.1530863789869, "KEPPRA": 0.1753981494966424, "KEYTRUDA": 0.240446502512814, "LANTUS": 0.3941941507171693, "LATUDA": 0.629781220107246, "LYNPARZA": 1.0311681893838147, "LYRICA": 0.7451410787531463, "MICARDIS": 1.052675371449828, "MIRCERA": 2.00521205189836, "NEXAVAR": 0.2817249676379184, "OPSUMIT": 0.2758031563753657, "PEGINTRON": 0.4321116911659743, "PLAVIX": 0.1886368007879331, "RINVOQ": 1.6226781495222664, "ROACTEMRA": 0.416242349060123, "SIMPONI": 0.9923133489728992, "SPIKEVAX": 0.0220119982326082, "STALEVO": 5.769176202321302, "STELARA": 0.3233752752140372, "STRIBILD": 24.913703256263304, "SUBOXONE": 0.4612373665272134, "SUTENT": 0.628428417356024, "TAGRISSO": 2.645747600499752, "TOVIAZ": 0.9581554814660292, "TOZINAMERAN": 0.0284592248317259, "TRACLEER": 0.3597525342924662, "TRUVADA": 25.590753011490605, "VAXZEVRIA": 0.0286825781829069, "VIAGRA": 0.374696667148689, "VIREAD": 11.318158613347029, "XELJANZ": 1.6729427683022224, "XOFIGO": 2.385089294128976, "XOLAIR": 0.8295686593073143, "XTANDI": 2.0313533656356904, "ZYPREXA": 0.2080589190567104, "null": 0.4740953201881758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4808.json
index 7e0fdad3cd6..6ed6d3e8c0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4808.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4808.json
@@ -1 +1 @@
-{"ALIMTA": 5.458262979281818, "ASPARAGINASE": 20.430810276701774, "AVASTIN": 8.278959534084095, "BEVACIZUMAB": 3.8912272912641073, "BUSULFAN": 6.555732155237148, "CELLCEPT": 5.681425848949701, "CICLOSPORIN": 12.033758421331695, "CYTARABINE": 15.70552442011438, "DEXAMETHASONE": 1.7231745888067704, "DOCETAXEL": 4.176121464472854, "IRESSA": 9.047228067410376, "IRINOTECAN": 7.30531746594093, "KEYTRUDA": 1.1461395706283206, "METHOTREXATE": 17.08604728385845, "NEXAVAR": 2.7692695604274853, "SUTENT": 2.124562452622696, "TEMODAL": 12.403514266290706, "XELODA": 12.439607280393512, "null": 1.3092799962987915}
\ No newline at end of file
+{"OPSUMIT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4809.json
index fab7d9555f1..98fd3d12abd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4809.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4809.json
@@ -1 +1 @@
-{"null": 2.224121452268076}
\ No newline at end of file
+{"ADALIMUMAB": 22.765765025494105, "null": 0.6875802522490944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/481.json
index 70a01c75c7c..3e35b87c0dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/481.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/481.json
@@ -1 +1 @@
-{"ARANESP": 190.2727245056481, "EPOETIN": 349.5703420902292, "NEORECORMON": 816.2697011790758, "PEGASYS": 1.7488480861322795, "null": 2.472424226495301}
\ No newline at end of file
+{"null": 1.5847379641713213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4810.json
index 51a98a7d8e3..35c05d41dae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4810.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4810.json
@@ -1 +1 @@
-{"ABACAVIR": 1.617023883451738, "ABILIFY": 4.383188797993573, "ABRAXANE": 1.607538074785348, "ADCETRIS": 2.265747274505872, "ADVAGRAF": 5.17567030453581, "ALDARA": 1.3617639345721213, "ALEMTUZUMAB": 1.231500420399172, "ALIMTA": 5.364298037301018, "AMIKACIN": 2.658030388210914, "ARIPIPRAZOLE": 9.876281019446289, "ASPARAGINASE": 1.3621565397823017, "ATAZANAVIR": 1.273333570807956, "AUBAGIO": 1.9332987314129504, "AVASTIN": 2.7890573125360465, "AZACITIDINE": 2.618180303770428, "AZATHIOPRINE": 2.392263054654869, "BARACLUDE": 1.4153909623442982, "BASILIXIMAB": 5.887401224624318, "BELIMUMAB": 1.942347766322179, "BENLYSTA": 1.4981932014010473, "BETAFERON": 2.845662841897447, "BEVACIZUMAB": 4.698945038600277, "BLINATUMOMAB": 1.9260076671209263, "BOCEPREVIR": 9.296073098498242, "BORTEZOMIB": 1.922649494589128, "CABAZITAXEL": 2.059640393139203, "CAELYX": 4.094452483483853, "CANCIDAS": 4.744077546766662, "CAPECITABINE": 4.482413000593519, "CARFILZOMIB": 2.438133215444721, "CARMUSTINE": 1.9862240858538676, "CELLCEPT": 8.923749910207928, "CETUXIMAB": 5.308338791846951, "CICLOSPORIN": 1.3387384490566945, "CLADRIBINE": 4.44222378542556, "COAPROVEL": 1.3229118977245644, "COMBIVIR": 2.798437651650655, "COTELLIC": 1.0167015621317903, "CRIXIVAN": 1.1152430518703136, "CUBICIN": 2.218182652526236, "CYTARABINE": 2.5239899560495758, "DARZALEX": 1.8560039232766008, "DENOSUMAB": 1.694442051016121, "DEXAMETHASONE": 1.847301066654085, "DEXRAZOXANE": 11.870806265102384, "DOCETAXEL": 8.147973514141079, "DOLUTEGRAVIR": 1.7451199848136127, "DOXORUBICIN": 7.36564386485423, "EBIXA": 3.041880708768073, "EFAVIRENZ": 1.17105918513033, "EMEND": 1.3394817012030662, "EMTRICITABINE": 1.7310393286830923, "ENVARSUS": 8.228827180716044, "EPIVIR": 4.605438958206982, "ERBITUX": 3.0337516752732925, "ERLEADA": 1.2881605024077676, "EVEROLIMUS": 2.981597718104191, "FASLODEX": 2.537065233667765, "FILGRASTIM": 3.9119765681220486, "FULVESTRANT": 6.363089801299656, "FUZEON": 6.816101975563304, "GANCICLOVIR": 11.184021713047224, "GAZYVARO": 6.63119853651579, "GEFITINIB": 1.6485360145695451, "GILENYA": 1.4667567727453252, "GLIVEC": 1.8235375755790892, "HALAVEN": 21.3628244842576, "HERCEPTIN": 2.0095230153048336, "HUMAN": 1.0974859519929316, "HYCAMTIN": 11.89923373865077, "IBRANCE": 6.095799576866688, "IBUPROFEN": 1.0513950378096322, "IMATINIB": 1.351987788708232, "INCIVO": 6.723911925873681, "INFERGEN": 7.973762124647253, "INTERFERON": 1.6607786247454532, "INTRONA": 5.253062487466219, "IRINOTECAN": 5.283762298689871, "ISCOVER": 3.604698234888086, "JAKAVI": 1.5928893222492733, "JEVTANA": 6.748448957639394, "KALETRA": 1.7693447774379258, "KEPPRA": 3.10137704014513, "KESIMPTA": 1.083954469056811, "KIOVIG": 1.3454202623452198, "KISQALI": 10.860752295209371, "LEFLUNOMIDE": 2.056674393925776, "LEMTRADA": 2.3327519725294192, "LENALIDOMIDE": 1.8838740719050149, "LEVETIRACETAM": 1.1953311849822257, "LEVOFLOXACIN": 1.2105598804539783, "LONSURF": 7.582926750515908, "LUTATHERA": 5.28041612760406, "LUTETIUM": 7.012303433342856, "LYNPARZA": 2.4391107890161843, "MABCAMPATH": 4.59394493019408, "MABTHERA": 10.52508503688411, "MAVENCLAD": 2.39433463064217, "MEKINIST": 1.3945506381240402, "MERCAPTOPURINE": 10.909300572773898, "METHOTREXATE": 3.176384803800352, "MYCOPHENOLATE": 4.675234305738132, "NEULASTA": 3.3248667182508944, "NEVIRAPINE": 1.71480883504397, "OBINUTUZUMAB": 1.3798873678769483, "OLANZAPINE": 3.029217321782993, "OLAPARIB": 7.88560598918799, "PACLITAXEL": 7.077457290827546, "PANITUMUMAB": 2.493709518175643, "PANTOPRAZOLE": 1.5745749989803788, "PEGASPARGASE": 3.1753234105710217, "PEGASYS": 5.398825452045159, "PEGFILGRASTIM": 8.335218267401745, "PEGINTERFERON": 8.592014690829139, "PEGINTRON": 5.24453041822838, "PEMBROLIZUMAB": 1.2549459675978314, "PEMETREXED": 7.476794303000054, "PERJETA": 2.3851098462010696, "PERTUZUMAB": 3.2880506145431565, "PLAVIX": 1.1419598664776194, "PLEGRIDY": 4.76915987358359, "POTELIGEO": 2.788030074474355, "PRIVIGEN": 1.1534365394280264, "RADIATION": 5.927868342492429, "RAPAMUNE": 1.26440468116155, "REBETOL": 4.020799927642053, "REBIF": 2.181621907874316, "RIBAVIRIN": 3.0724237219492827, "RIBOCICLIB": 15.258175669243291, "RINVOQ": 1.1575183247364424, "RITUXIMAB": 3.784945212991589, "RIXATHON": 1.3898225554005896, "ROACTEMRA": 7.27509717547501, "RUXOLITINIB": 2.324104356528106, "SOLIRIS": 1.5975605241551765, "SORAFENIB": 1.434582089304956, "SPRYCEL": 1.686356350751631, "SUNITINIB": 4.028926241635756, "SUTENT": 2.419763332385862, "TACROLIMUS": 2.2104064797681637, "TAGRISSO": 1.2086764154936989, "TAMIFLU": 2.1455858788713704, "TASIGNA": 1.8017496242955184, "TAXOTERE": 15.417388750327724, "TEGAFUR": 9.691648078360767, "TEMODAL": 13.310108986627728, "TEMOZOLOMIDE": 10.172920643292162, "THALIDOMIDE": 1.9137305299284024, "THERAPEUTIC": 10.748193567293193, "THIOTEPA": 2.96137769703598, "TOCILIZUMAB": 4.049179285731845, "TOPOTECAN": 6.149278453926653, "TRABECTEDIN": 6.014067022917677, "TRODELVY": 2.173023630650995, "VECTIBIX": 2.432230712818792, "VENCLYXTO": 3.5229369564159736, "VENETOCLAX": 3.189345365182621, "VIMPAT": 1.2015955724137155, "XELODA": 3.282350316287402, "XOFIGO": 3.309170650389392, "YONDELIS": 5.256302080622599, "ZERBAXA": 55.47428453801862, "ZEVALIN": 16.92251773841379, "ZONISAMIDE": 2.571632092644756, "ZYPREXA": 2.025476611164348, "null": 1.4965865493997788}
\ No newline at end of file
+{"null": 1.0694489479752738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4811.json
index 886199c8d75..6d91272f152 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4811.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4811.json
@@ -1 +1 @@
-{"null": 1.9021034470265756}
\ No newline at end of file
+{"FORSTEO": 35.04906616736135, "null": 1.0460471173104462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4812.json
index e79f9230936..20f05556124 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4812.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4812.json
@@ -1 +1 @@
-{"null": 1.730357858957824}
\ No newline at end of file
+{"VIAGRA": 18.65750474614494, "null": 18.1559053912446}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4813.json
index 664bbfb8775..1ae218cf760 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4813.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4813.json
@@ -1 +1 @@
-{"null": 1.4255256721462233}
\ No newline at end of file
+{"ATRIPLA": 4.322859759935198, "FORSTEO": 29.293571628827525, "null": 0.8832253996055756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4814.json
index e866bea8efb..9a766f531e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4814.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4814.json
@@ -1 +1 @@
-{"AUBAGIO": 38.2030645950247}
\ No newline at end of file
+{"ATRIPLA": 10.80446523489447, "IRBESARTAN": 45.02893113078954, "LANTUS": 3.616486077161892, "STRIBILD": 7.70458096946798, "TRUVADA": 3.232855366542165, "null": 0.8838013917961243}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4815.json
index 12ef1c34aca..57403427256 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4815.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4815.json
@@ -1 +1 @@
-{"ABILIFY": 2.9038114404415607, "BIKTARVY": 3.1649080604128565, "BRINTELLIX": 23.455325710609827, "BUPIVACAINE": 6.772424126502291, "CHAMPIX": 3.200033211705383, "CIALIS": 14.529117802560044, "CYMBALTA": 3.36527236295115, "LYRICA": 1.6549911189139752, "OLANZAPINE": 1.6909507755279498, "PEGASYS": 1.085131112543151, "SUBOXONE": 3.742848708553416, "TESTOSTERONE": 7.07597971587408, "UROREC": 34.48602214236978, "VIAGRA": 2.5741502400427145, "ZYPREXA": 2.4291218071755067, "null": 4.8946350951620925}
\ No newline at end of file
+{"AFINITOR": 9.769120522963082, "ATRIPLA": 9.074203406325076, "FORSTEO": 19.424240771987712, "TRUVADA": 6.520159988183859, "null": 0.8722684183116406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4816.json
index 4d85aaa5f16..c42db5e103e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4816.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4816.json
@@ -1 +1 @@
-{"CHAMPIX": 4.353121827090177, "ZYPREXA": 5.011274901838199, "null": 2.2930071897638866}
\ No newline at end of file
+{"ZEPATIER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4817.json
index a6850c7a084..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4817.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4817.json
@@ -1 +1 @@
-{"ABILIFY": 4.705213970829912, "AIMOVIG": 30.87106876122801, "BRINTELLIX": 7.98195071012703, "CHAMPIX": 5.563645123697841, "CIALIS": 56.07065819962056, "CYMBALTA": 1.2275708314524203, "OLANZAPINE": 5.217943264426953, "PANTOPRAZOLE": 8.035659682944493, "SIFROL": 68.8112909051405, "STALEVO": 20.785353313834342, "VIAGRA": 9.50189564743061, "null": 1.822934016408282}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4818.json
index d6f481a6b3c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4818.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4818.json
@@ -1 +1 @@
-{"null": 1.043373384120751}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4819.json
index 8487857520a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4819.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4819.json
@@ -1 +1 @@
-{"COMIRNATY": 2.743845232190221}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/482.json
index c8faabda0c2..808f720ad85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/482.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/482.json
@@ -1 +1 @@
-{"HUMALOG": 43.08463888836064, "INSULIN": 105.00069486159164, "LEVEMIR": 60.51446007654668, "NOVORAPID": 286.48426815482804}
\ No newline at end of file
+{"BUDESONIDE": 116.0331301026762, "CICLOSPORIN": 43.86125711231584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4820.json
index 8d4c5b0a70f..6cb99988921 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4820.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4820.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.251627887996571, "COMIRNATY": 1.3820032469133046, "COSENTYX": 4.228770675892275, "JARDIANCE": 1.2728746438612557, "KEYTRUDA": 8.401622223797961, "PEGASYS": 1.0452773946464131, "PEMBROLIZUMAB": 8.72861911035164, "TOZINAMERAN": 1.2502739416501578, "TWINRIX": 7.405725764967803, "ZOSTAVAX": 3.0324280435932334}
\ No newline at end of file
+{"ABIRATERONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4821.json
index 0b32d400487..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4821.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4821.json
@@ -1 +1 @@
-{"COMIRNATY": 2.2413257631804453, "JARDIANCE": 25.352570229184767, "TOZINAMERAN": 1.4986046182224182}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4822.json
index 61e93ac646e..f3ef05fc458 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4822.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4822.json
@@ -1 +1 @@
-{"CICLOSPORIN": 31.858958687588725, "OPTIMARK": 45.30524993893318, "RINVOQ": 34.57120774683536}
\ No newline at end of file
+{"AZILECT": 251.44086568418496, "CARBIDOPA": 195.44164740913732, "COMIRNATY": 0.3137520984255739, "COMTAN": 67.19127695877536, "SPIKEVAX": 0.6095613070788486, "STALEVO": 69.77136538612962, "TOZINAMERAN": 0.6495259154226957, "VAXZEVRIA": 4.588452646104823, "null": 0.5181382646489006}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4823.json
index ea33c773565..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4823.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4823.json
@@ -1 +1 @@
-{"ALIMTA": 7.922876019064592, "CICLOSPORIN": 1.6753296431684226, "ELIQUIS": 1.198668832198886, "IPILIMUMAB": 13.016764537000531, "KEPPRA": 1.6274111675157636, "KEYTRUDA": 12.91858344233929, "OPDIVO": 6.208279406740189, "PEMBROLIZUMAB": 15.455843731148954, "PLAVIX": 1.5445698918510615, "null": 1.2483030323487254}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4824.json
index 624170e33ad..afba1ec60a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4824.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4824.json
@@ -1 +1 @@
-{"null": 1.731601702195374}
\ No newline at end of file
+{"ADALIMUMAB": 12.153078338121496, "AFINITOR": 2.0950676331265328, "ALIGN": 106.10161277887882, "AMINOSALICYLIC": 65.57882864305256, "AUBAGIO": 2.2391407422368284, "AVAMYS": 28.896819751538786, "AZATHIOPRINE": 2.6215034319318686, "BUDESONIDE": 40.476029735495786, "CELECOXIB": 3.591085642591316, "CICLOSPORIN": 0.2722703332434977, "CIMZIA": 1.6627203055785866, "CLOPIDOGREL": 0.3501902371990877, "COMIRNATY": 0.1395938054922157, "COSENTYX": 0.4733649681777329, "ELIQUIS": 0.2616773082644065, "ENTRESTO": 0.6257191078108146, "ENTYVIO": 28.073236052895368, "ESOMEPRAZOLE": 2.0133379178023363, "EXJADE": 1.0120361797727542, "FORSTEO": 0.5197474567841684, "HUMALOG": 0.2401462755553045, "HUMIRA": 15.069769653552475, "IBRANCE": 0.3336840385872317, "INFLECTRA": 14.483309116064094, "INFLIXIMAB": 35.87700965493708, "JANUMET": 1.095291231442208, "JARDIANCE": 0.4521396976097875, "KEYTRUDA": 0.2895194750987083, "NEXAVAR": 0.9940717104265056, "OFEV": 1.728475731436441, "OPSUMIT": 0.4165136616526095, "PANTOPRAZOLE": 3.6620865520174, "PEGASYS": 0.7384857808370056, "PLAVIX": 0.2546261761891242, "PREGABALIN": 16.269330528922094, "REMICADE": 8.053457801901756, "REMSIMA": 24.48324583090658, "RINVOQ": 3.602311933750688, "ROTATEQ": 4.446760420273724, "SIMPONI": 2.1545851650890784, "SPIKEVAX": 0.1600290511349681, "STELARA": 2.949603249932357, "STIVARGA": 0.8861280753446434, "SUTENT": 1.3392272494152262, "TEDUGLUTIDE": 42.62433073776352, "TOZINAMERAN": 0.2811651495906376, "VAXZEVRIA": 0.1366292851611593, "VEDOLIZUMAB": 17.89618934955584, "VOTRIENT": 0.9565241534593708, "XELJANZ": 10.326830726255375, "XTANDI": 0.6310058493792106, "null": 0.5824974460263159}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4825.json
index cffc2e23f0e..35c05d41dae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4825.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4825.json
@@ -1 +1 @@
-{"COSENTYX": 15.520567113427768}
\ No newline at end of file
+{"null": 1.0694489479752738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4826.json
index 731721ced7c..a950252e298 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4826.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4826.json
@@ -1 +1 @@
-{"null": 12.865521889241586}
\ No newline at end of file
+{"null": 1.7917648510406683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4827.json
index bde3b857dfe..8a375be457a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4827.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4827.json
@@ -1 +1 @@
-{"null": 3.3226791819194994}
\ No newline at end of file
+{"VAXZEVRIA": 1.2478426946968209, "null": 0.5063454530123213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4828.json
index dca9c745ce5..de75739c64a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4828.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4828.json
@@ -1 +1 @@
-{"HUMALOG": 8.466224930517543, "OPTIMARK": 39.14153631062759, "null": 1.5619699003156953}
\ No newline at end of file
+{"null": 1.7523684511692792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4829.json
index a1b8923e348..997db83072f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4829.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4829.json
@@ -1 +1 @@
-{"null": 1.7549963703378892}
\ No newline at end of file
+{"AUBAGIO": 2.354134427603052, "AVAMYS": 19.744389105399204, "CHAMPIX": 4.082880585803816, "CIMZIA": 0.5850370288129599, "COMIRNATY": 0.1024071911715985, "CYMBALTA": 1.6979004633589627, "ENBREL": 4.000052796429732, "ESBRIET": 2.838005618234625, "FASENRA": 3.488487622535633, "GARDASIL": 1.1312642246039888, "HUMALOG": 1.7538855053095337, "IBRANCE": 1.4345418742240772, "KEPPRA": 3.263322234505051, "LANTUS": 2.051561823295374, "LATUDA": 5.47558127092253, "LEFLUNOMIDE": 16.509879225402386, "LEVETIRACETAM": 1.6168598597448476, "LYRICA": 1.9324341706115808, "MEPOLIZUMAB": 2.895621726559348, "OLANZAPINE": 4.375347611624641, "OMALIZUMAB": 10.278697576028922, "PEGASYS": 0.7540671454162529, "PEGINTRON": 1.109943457636979, "RINVOQ": 2.5417027037971858, "SPIKEVAX": 0.2161420527446396, "SUTENT": 0.5546718446249163, "TOZINAMERAN": 0.9313637127328828, "TRELEGY": 2.3491978908640534, "VAXZEVRIA": 0.0885682506544236, "VIAGRA": 2.4516875379082688, "XELJANZ": 2.3802364664172453, "XOLAIR": 3.0572908959121645, "ZOSTAVAX": 2.8170381887336067, "null": 1.6699655840627825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/483.json
index 9ebfbb4eea1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/483.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/483.json
@@ -1 +1 @@
-{"APIDRA": 59.33583015662892, "HUMALOG": 45.96755765258344, "INSULIN": 102.09304959519568, "LANTUS": 11.4827297063163, "LEVEMIR": 42.24135693190912, "NOVORAPID": 110.0534227974708}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4830.json
index ea87f19fb76..5861639d9b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4830.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4830.json
@@ -1 +1 @@
-{"null": 3.552772685977802}
\ No newline at end of file
+{"MYCOPHENOLATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4831.json
index f3e6aa83c92..ac9b0f2262d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4831.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4831.json
@@ -1 +1 @@
-{"null": 1.2028697269537385}
\ No newline at end of file
+{"GARDASIL": 12.471320486033791, "SPIKEVAX": 12.69405066806334, "VAXZEVRIA": 1.614155934146969}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4832.json
index 7da0857eab1..1253d93047f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4832.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4832.json
@@ -1 +1 @@
-{"null": 1.19653130101283}
\ No newline at end of file
+{"ACLIDINIUM": 13.226810655026258, "AFINITOR": 1.0501117239013256, "ALENDRONATE": 46.19825742893999, "ALIMTA": 0.5156855799182795, "ANORO": 35.224706129151855, "APIXABAN": 22.627245272351654, "ARANESP": 1.3245690412421434, "ARAVA": 0.0871355466958537, "ARIPIPRAZOLE": 0.3116984699600069, "AUBAGIO": 0.4906704418333665, "AVAMYS": 47.93991502446215, "AVASTIN": 0.4138035822206083, "AZATHIOPRINE": 4.927509065122937, "AZOPT": 37.54490072368649, "BENRALIZUMAB": 83.07725265669586, "BEVACIZUMAB": 0.6346127113340451, "BOSULIF": 2.481239568516834, "BUDESONIDE": 34.038595651177395, "CANAGLIFLOZIN": 63.22364631229287, "CELECOXIB": 1.8940499126844603, "CELLCEPT": 0.3933112077796887, "CLOPIDOGREL": 1.092596567507602, "COMIRNATY": 0.0507625761015734, "CYMBALTA": 0.1645206529442734, "DAXAS": 44.69104487310736, "DESLORATADINE": 8.439381944953862, "DEXAMETHASONE": 2.0017129261253546, "DUAKLIR": 52.760914489237024, "DUPIXENT": 3.3888005614164407, "ELIQUIS": 0.8718069919821055, "ESOMEPRAZOLE": 1.631520099628615, "EXJADE": 1.2825102233539076, "FASENRA": 1.4828566366778246, "FASLODEX": 4.857797451427605, "FLUTICASONE": 21.581871607110187, "FORSTEO": 0.3172870131685416, "FULVESTRANT": 2.303349306598948, "GLYCOPYRRONIUM": 66.17129266597702, "HIZENTRA": 0.9496018607940592, "HUMIRA": 0.2959204509478557, "IBRANCE": 15.270411036050346, "IBUPROFEN": 0.56882767852869, "ICLUSIG": 2.176171772150969, "INCIVO": 0.8050568400107712, "INCRUSE": 7.719024628920669, "INLYTA": 0.6864408754093995, "INVOKANA": 6.299675955740804, "IRON": 2.378942861899194, "JAKAVI": 4.174054840512145, "JANUMET": 0.9322363479998208, "JANUVIA": 0.8380239404962037, "KEPPRA": 0.1968000754877305, "KISQALI": 1.2227759288841364, "LEVOFLOXACIN": 0.4674242281795119, "LIRAGLUTIDE": 88.46421785977161, "LONSURF": 6.023692379471247, "LYNPARZA": 2.134481421043976, "MEPOLIZUMAB": 29.987776959368123, "METHOTREXATE": 0.2941287838399671, "NEULASTA": 3.829320361628729, "NINLARO": 2.5888930296866453, "NUCALA": 48.48616911498753, "OMALIZUMAB": 7.520788507715626, "OPSUMIT": 1.086374454054559, "OZEMPIC": 9.589587649052197, "PANTOPRAZOLE": 6.217705174589401, "PEGASYS": 2.665764304262987, "PEGINTRON": 0.904790738258329, "PLAVIX": 0.4109790402090341, "PLEGRIDY": 4.91205944294301, "PREGABALIN": 3.672295055233335, "REBETOL": 1.8755685764102328, "REVATIO": 0.7848012355782642, "REVLIMID": 1.7277076968177187, "RINVOQ": 0.4540731761892536, "ROACTEMRA": 0.5916467432536983, "RUBRACA": 11.69700743732657, "SIMPONI": 0.2249639848884508, "SOLIRIS": 1.651287977116059, "SPIKEVAX": 0.0516079862352283, "SPRYCEL": 0.9488963661919236, "SUTENT": 1.6792810591732763, "TASIGNA": 1.008488733343236, "TELMISARTAN": 5.310903785908307, "TOZINAMERAN": 0.0763512268316425, "TRACLEER": 0.4202144770226544, "TRELEGY": 0.7056546565091696, "UMECLIDINIUM": 36.297922636280944, "VARENICLINE": 19.295760722661964, "VAXZEVRIA": 0.0403614886566044, "VFEND": 0.8490186902484675, "VIAGRA": 0.3454934128610678, "XARELTO": 0.7820820406653944, "XELJANZ": 0.5442783627597765, "XOFIGO": 6.233720673247319, "XOLAIR": 1.1950237916814883, "XTANDI": 0.4153051704583083, "null": 0.582541544166749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4833.json
index 4163b751af1..e7d6569f286 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4833.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4833.json
@@ -1 +1 @@
-{"ATRIPLA": 1.0106697894068906, "CIMZIA": 5.20665111649671, "HUMALOG": 2.0414072396363627, "LANTUS": 1.8897863284130176, "OMALIZUMAB": 9.482026379166994, "SIMPONI": 2.7655278369001755, "SUBOXONE": 3.6305018078054094, "TRUVADA": 1.490403985729282, "XELJANZ": 7.581175158983913, "XOLAIR": 3.2013016684220634, "null": 1.5095509202037225}
\ No newline at end of file
+{"AFINITOR": 1.0270972136225922, "ALIMTA": 1.2578819151628629, "AVASTIN": 1.7628227601855495, "AZACITIDINE": 4.470106748047323, "BEVACIZUMAB": 1.566854623808677, "BOSULIF": 3.233179046733889, "CELLCEPT": 0.8929405243792862, "CICLOSPORIN": 0.7652688910906232, "COMIRNATY": 0.0097695238501265, "CYTARABINE": 2.756190249461182, "DEXAMETHASONE": 4.758344184158699, "DOCETAXEL": 1.3273066674618397, "ELIQUIS": 1.3506642983977886, "EXJADE": 3.914746158348806, "FASLODEX": 6.016758305898734, "FULVESTRANT": 3.763892140408255, "IBRANCE": 42.477152671963, "ICLUSIG": 3.9702374987291673, "JAKAVI": 6.864549410321958, "KEYTRUDA": 0.5295926593942116, "KYMRIAH": 11.05449778336716, "LYNPARZA": 2.6267400513663084, "MABTHERA": 6.508644197216642, "MEKINIST": 1.4290877997626783, "NEULASTA": 1.6884069655847629, "NINLARO": 24.739155655112604, "OPSUMIT": 0.8708448710879577, "PEGASYS": 8.724457781966105, "PEGINTERFERON": 1.248062285494382, "PEGINTRON": 1.8937542893391224, "PLAVIX": 0.5323702326022666, "REVLIMID": 38.35147417025899, "RITUXIMAB": 1.6223081375375297, "SOLIRIS": 0.9180381098182664, "SPRYCEL": 12.55605821348726, "SUTENT": 2.001570008182767, "TASIGNA": 4.369205166795656, "VFEND": 1.0402685176887836, "VOTRIENT": 0.7644803462716889, "XELJANZ": 0.6114014506797228, "XTANDI": 3.4862464490880787, "null": 1.6437554790213331}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4834.json
index 330d5b27650..20fe88cac7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4834.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4834.json
@@ -1 +1 @@
-{"ABILIFY": 3.3090728013630875, "APIXABAN": 3.8886672281490826, "BIKTARVY": 19.833474889458245, "CIMZIA": 1.4311120074447494, "ELIQUIS": 1.2416299191014983, "FAMPYRA": 8.958605722647864, "FORSTEO": 3.0017927295228373, "GARDASIL": 2.636477003373537, "HEMLIBRA": 20.438175479098213, "HUMIRA": 2.303245571688715, "IBRANCE": 1.3396615427193823, "LANTUS": 1.8924442983476328, "LYRICA": 3.9034106916524753, "METHOTREXATE": 2.1705543009091555, "OMALIZUMAB": 7.911694007255219, "RITUXIMAB": 6.044906870906838, "SIMPONI": 2.2760218882182754, "XELJANZ": 4.783110454910474, "XOLAIR": 3.8122382356983993, "ZOSTAVAX": 5.649413402354802, "null": 1.1534121759397866}
\ No newline at end of file
+{"null": 0.776601708699106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4835.json
index f1d2b6dc1d1..f9803a26d8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4835.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4835.json
@@ -1 +1 @@
-{"DARZALEX": 211.9208540814577, "DEXAMETHASONE": 43.01342858391224}
\ No newline at end of file
+{"GARDASIL": 33.72115178371756, "SPIKEVAX": 9.162685007412223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4836.json
index e4e0045dbeb..7a086972a23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4836.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4836.json
@@ -1 +1 @@
-{"CARFILZOMIB": 478.0959556872116}
\ No newline at end of file
+{"IPILIMUMAB": 51.11545576917631, "KEYTRUDA": 117.98497221773302, "OPDIVO": 176.56552251434485, "PEMBROLIZUMAB": 35.50204880131232, "null": 0.0778444714409719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4837.json
index 615d58d43c9..45d0ecd1bcd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4837.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4837.json
@@ -1 +1 @@
-{"INVOKANA": 464.515703934641, "JARDIANCE": 35.11456236835319}
\ No newline at end of file
+{"COMIRNATY": 0.611747686568373, "null": 1.6063777337432468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4838.json
index 7572033ea98..63305cbe3fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4838.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4838.json
@@ -1 +1 @@
-{"null": 2.8422024405568638}
\ No newline at end of file
+{"ACETYLSALICYLIC": 328.6286408623495, "AIMOVIG": 1.650962414093265, "ARAVA": 2.380394839153929, "AUBAGIO": 3.323534194999604, "BENLYSTA": 2.9791718978037025, "BORTEZOMIB": 30.08609264414136, "CHAMPIX": 1.3352896803341787, "COMIRNATY": 0.2690126920934546, "CYMBALTA": 0.8381885649679527, "FENTANYL": 19.14350626717185, "GARDASIL": 1.4727355021543735, "IBRANCE": 1.3444237990972954, "JANUMET": 2.341312506092806, "PEGASYS": 1.0647837019598947, "PLAVIX": 1.37474859208567, "SPIKEVAX": 0.2323300711379657, "SUTENT": 1.6067608310044954, "TOZINAMERAN": 0.4416442296850693, "VAXZEVRIA": 0.3027732994930815, "XELJANZ": 2.2770319143352507, "ZOSTAVAX": 1.423797368138999, "null": 1.1330351743264058}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4839.json
index eceb72fd42c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4839.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4839.json
@@ -1 +1 @@
-{"SUBOXONE": 19.798595992301724, "null": 1.327921547200984}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/484.json
index 3f67326261d..92b0750930f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/484.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/484.json
@@ -1 +1 @@
-{"APIDRA": 85.92377329816652, "HUMALOG": 44.50766885741264, "INSULIN": 86.28165917649825, "LANTUS": 35.35467224977318, "LEVEMIR": 65.54256120743777, "NOVORAPID": 125.76838697673116}
\ No newline at end of file
+{"ATRIPLA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4840.json
index 10989c135f7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4840.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4840.json
@@ -1 +1 @@
-{"ADALIMUMAB": 4.802418510331047, "ARAVA": 8.839749034402201, "ENBREL": 4.49399211616613, "HUMALOG": 2.2501366278233483, "null": 1.399370174741408}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4841.json
index 37f7eb5978f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4841.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4841.json
@@ -1 +1 @@
-{"AUBAGIO": 1.0232625549037129, "COMIRNATY": 3.785311125001844, "COVID19": 1.049247275502652, "JCOVDEN": 12.778438947000025, "SHINGRIX": 1.3295222446240167, "SPIKEVAX": 4.774105907953095, "TOZINAMERAN": 1.289221647223691, "VAXZEVRIA": 6.218275209524858}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4842.json
index 50d6c63243c..6f847dacf5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4842.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4842.json
@@ -1 +1 @@
-{"ATRIPLA": 30.61004843188345, "TRUVADA": 17.986323589381943}
\ No newline at end of file
+{"null": 0.5059414636737627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4843.json
index 21f2a2d2f3d..60dbfd4175f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4843.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4843.json
@@ -1 +1 @@
-{"null": 6.639262375097111}
\ No newline at end of file
+{"LEVOFLOXACIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4844.json
index 1212a11bdeb..5df86e54ff3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4844.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4844.json
@@ -1 +1 @@
-{"COMIRNATY": 1.50645655963597, "COVID19": 2.1169363616894614, "TOZINAMERAN": 1.3924788478781656, "VAXZEVRIA": 1.4109115253108246}
\ No newline at end of file
+{"ALEMTUZUMAB": 13.854087202383887, "AMIKACIN": 73.55685619394276, "ASPARAGINASE": 18.50180720157124, "AZACITIDINE": 27.554173674062927, "BUSULFAN": 30.64068841417857, "CANCIDAS": 100.61353957184764, "CASPOFUNGIN": 207.0090693552395, "CELLCEPT": 7.526651982913923, "CICLOSPORIN": 8.027489512917285, "CYTARABINE": 32.423125896178675, "POSACONAZOLE": 63.97711774661576, "VORICONAZOLE": 17.673646397854935, "null": 0.5703891247560225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4845.json
index 583fda1e143..23c511d2207 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4845.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4845.json
@@ -1 +1 @@
-{"ACLASTA": 12.253353225594433, "ADVATE": 20.54735479041749, "ALLERGY": 154.76060111989247, "APIDRA": 1.8462213645806305, "AUBAGIO": 1.26334041483154, "BENLYSTA": 4.100039900216026, "BYDUREON": 2.2469765588098336, "BYETTA": 2.211694638895096, "COSENTYX": 1.057991777263655, "CYMBALTA": 1.24829173910561, "ELIQUIS": 3.268037144614117, "EVISTA": 1.5972666357758816, "FAMPYRA": 1.5743123854077103, "FORSTEO": 1.6566521964265195, "FORXIGA": 2.185039692439216, "GALVUS": 2.77480984054728, "HEMLIBRA": 8.90856941147081, "HUMALOG": 6.068354649300743, "HUMIRA": 2.4999468389191617, "IBRANCE": 2.7442242848153064, "ILARIS": 20.03756307875125, "INSULIN": 2.186108042313221, "JANUVIA": 1.1371834629557849, "JARDIANCE": 2.391419129335128, "KOVALTRY": 63.36811877106136, "LANTUS": 3.802973060122879, "LEVEMIR": 1.035527728375797, "LYRICA": 1.9506928457694028, "MEPOLIZUMAB": 1.7853735747940167, "METHOTREXATE": 1.6771697641584673, "NUCALA": 1.6206144339095645, "OMALIZUMAB": 1.0751848698746944, "OPSUMIT": 1.6836050906732898, "PREGABALIN": 1.2683446881107463, "REMICADE": 3.122272862381916, "REVATIO": 1.8982918491517704, "RITUXIMAB": 1.1315082002661965, "ROACTEMRA": 1.4388252360512706, "SIMPONI": 1.7796729670806426, "SOMAVERT": 28.849978134739857, "STELARA": 1.1083926073232313, "SUBOXONE": 3.5477221890592454, "SUTENT": 3.076252804424091, "TOVIAZ": 1.5694019315014829, "TOZINAMERAN": 1.120668080212885, "TRESIBA": 5.233675930073246, "TRULICITY": 1.1514371493250724, "VELTASSA": 2.5276264457264697, "VIAGRA": 3.9514352262055614, "XELJANZ": 6.265018893940134, "XYREM": 3.89101592731847, "ZOSTAVAX": 3.270131234152873, "null": 1.1307136025359117}
\ No newline at end of file
+{"JARDIANCE": 110.99003288205569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4846.json
index ba179c806a5..0e46b93ad47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4846.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4846.json
@@ -1 +1 @@
-{"ACLASTA": 62.08834775715734, "ELIQUIS": 2.7097724360430706, "FASLODEX": 4.803165365036792, "METHOTREXATE": 4.991275058257167, "OPTIMARK": 8.983798875109375, "PEGASYS": 2.6378063666562963, "SIMPONI": 7.881293011568928, "SUTENT": 1.1309869760875717, "TOZINAMERAN": 3.268402775107524, "VAXZEVRIA": 1.0280707056170495, "XELJANZ": 3.554656696907944}
\ No newline at end of file
+{"JARDIANCE": 95.3145387929366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4847.json
index f64a7477a4b..dc72c69e68f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4847.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4847.json
@@ -1 +1 @@
-{"APIDRA": 5.10137353160867, "ARAVA": 2.578357070322252, "BENLYSTA": 9.882498156932748, "CIMZIA": 2.737561857072276, "HIZENTRA": 7.896683055121838, "HUMIRA": 7.862596051523624, "IBRANCE": 1.692477797322318, "LANTUS": 5.096640728170159, "SIMPONI": 23.25870233215681, "STELARA": 2.7093565402621667, "VOTRIENT": 5.278391815847565, "XELJANZ": 7.807236902522109, "ZOSTAVAX": 2.22364390440566, "null": 1.1258878711157407}
\ No newline at end of file
+{"ACLIDINIUM": 3630.822227419112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4848.json
index 93161c9f3d0..5c1f69d3dd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4848.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4848.json
@@ -1 +1 @@
-{"null": 4.373749325542392}
\ No newline at end of file
+{"CASPOFUNGIN": 385.0219473762471, "null": 0.4666526541053096}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4849.json
index ad31c9dc21c..aab8ec88bed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4849.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4849.json
@@ -1 +1 @@
-{"null": 7.122006539340007}
\ No newline at end of file
+{"XELJANZ": 8.167187275228661, "null": 0.5928168212747869}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/485.json
index 992596c9723..c3b48313350 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/485.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/485.json
@@ -1 +1 @@
-{"ANAKINRA": 10.334892715896435, "KALETRA": 16.356085092997674, "PEGINTRON": 4.091608767835779, "TOZINAMERAN": 1.1825362617824826, "null": 2.4171275984934173}
\ No newline at end of file
+{"ATRIPLA": 17.917211846154192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4850.json
index edbf64781b0..9fb030657b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4850.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4850.json
@@ -1 +1 @@
-{"SUBOXONE": 12.683690788368708, "null": 1.140467804756307}
\ No newline at end of file
+{"ADALIMUMAB": 0.0868545733329357, "AFINITOR": 0.4654671377880545, "ALEMTUZUMAB": 3.8640739939578608, "APIXABAN": 0.747816025317223, "ARAVA": 0.501048451493037, "ASPARAGINASE": 16.98301266954229, "AUBAGIO": 1.5021439698975, "AZACITIDINE": 8.864341881982472, "AZATHIOPRINE": 2.143849903975345, "BENLYSTA": 1.260141296143794, "BEVACIZUMAB": 0.9399252003901992, "BUDESONIDE": 1.7731491664615624, "BUSULFAN": 6.098309732925757, "BYDUREON": 0.6979604671479499, "CANCIDAS": 19.843744589406505, "CARMUSTINE": 7.795338135475069, "CASPOFUNGIN": 22.41245824824658, "CELLCEPT": 2.491695673806795, "CHAMPIX": 0.2800968124850259, "CICLOSPORIN": 5.256933537213028, "CIMZIA": 3.2534511514182567, "COMBIVIR": 1.968519264916109, "COMIRNATY": 0.1242955236473782, "COSENTYX": 5.681236982286603, "CRESEMBA": 9.33814757027215, "CYMBALTA": 0.2615676978626161, "CYTARABINE": 6.76938673192877, "DEXAMETHASONE": 1.798113590144698, "ELIQUIS": 0.5606463467718691, "ENBREL": 0.452277709524095, "ENTRESTO": 0.472166969014562, "ENTYVIO": 0.8282323533063852, "ESBRIET": 0.7506254224127988, "ESOMEPRAZOLE": 3.2405529213131743, "EXJADE": 0.797746378475533, "FASLODEX": 1.0810670442708172, "FILGRASTIM": 2.775285032924556, "FORSTEO": 0.3861801394375536, "FORXIGA": 20.0155600915012, "GANCICLOVIR": 7.118218398976823, "GARDASIL": 0.9228985372523562, "HIZENTRA": 2.0083459946113664, "HUMALOG": 1.269053135215425, "HUMIRA": 2.819377073296562, "HYDROCORTISONE": 2.469442753759983, "IBRANCE": 1.1830532991273908, "ICLUSIG": 1.4326526135047977, "INVOKANA": 5.833651037895012, "JAKAVI": 1.0390305634557129, "JANUMET": 0.5563995566580369, "JANUVIA": 1.2418419549577346, "JARDIANCE": 37.46073701844024, "KAFTRIO": 1.320896654225234, "KEYTRUDA": 0.2837994286918816, "LANTUS": 0.638562856719227, "LEVEMIR": 0.7715894416764688, "LEVOFLOXACIN": 0.5598842013599392, "LYRICA": 0.5718507771150348, "MEPOLIZUMAB": 5.479801799498355, "METHOTREXATE": 4.668568381938914, "MYCAMINE": 12.80968933405287, "MYCOPHENOLATE": 8.879060897265878, "NOXAFIL": 8.591884072473107, "NUCALA": 0.4554370070274138, "OFEV": 1.336977235081577, "OPSUMIT": 0.606407910493955, "PEGASYS": 0.8441937079139794, "PEGINTRON": 1.415793560949911, "POSACONAZOLE": 22.56871578978878, "RELVAR": 1.9729366288793773, "REMICADE": 3.5226170216749817, "RINVOQ": 1.713660817153971, "RITUXIMAB": 1.471012337042534, "ROACTEMRA": 0.5684043298420303, "SIMPONI": 1.232212043635048, "SKYRIZI": 4.237620919927919, "SOLIRIS": 1.8333342899409948, "SPIKEVAX": 0.1111848365374314, "STELARA": 1.3467830873238384, "SUBOXONE": 0.3455463267188495, "SUTENT": 1.0814911127454216, "TACROLIMUS": 6.372367484662919, "TOZINAMERAN": 0.1554335226566023, "TRELEGY": 2.049104031761188, "TREMFYA": 1.767801538344073, "TRULICITY": 0.5708137321295238, "VAXZEVRIA": 0.0626766967435237, "VENETOCLAX": 5.481790008746805, "VFEND": 8.527562568612923, "VORICONAZOLE": 10.188354554892197, "XELJANZ": 2.8633427657959003, "XOLAIR": 0.7647932775651416, "XYREM": 1.92883693954689, "ZOSTAVAX": 1.2904236457205769, "ZYPREXA": 0.6381124654687942, "null": 0.7882285075828772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4851.json
index 5780fe6256b..2eead2e69f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4851.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4851.json
@@ -1 +1 @@
-{"IBRANCE": 2.017281019146413, "METHOTREXATE": 5.037144722518463, "PEGASYS": 1.2278018503504151, "SHINGRIX": 6.88812791092473, "SUTENT": 4.015342487820515, "TOZINAMERAN": 1.22647284049522, "TRELEGY": 6.989093735581003, "VFEND": 5.656052732896853, "XELJANZ": 1.3317494385703152, "null": 1.4404264978235022}
\ No newline at end of file
+{"null": 1.5111451146838542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4852.json
index ecc9cfd93bb..4dc70348cd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4852.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4852.json
@@ -1 +1 @@
-{"ABACAVIR": 8.50009195042409, "COMBIVIR": 26.47207259420638, "PREGABALIN": 45.517006873899646, "SUTENT": 1.779402256077714, "TOZINAMERAN": 1.1891512091888374, "null": 1.305520562824036}
\ No newline at end of file
+{"ECULIZUMAB": 1916.125622920623, "null": 2.4931470547475416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4853.json
index b6e0e43f4de..3b281e41a8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4853.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4853.json
@@ -1 +1 @@
-{"RITUXIMAB": 17.210922557143547, "SUTENT": 2.245602234128931, "TOZINAMERAN": 1.3510065373978042, "null": 2.201223209577031}
\ No newline at end of file
+{"RELVAR": 340.2434842976009, "TRELEGY": 86.83023986528065, "null": 1.2448464290104064}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4854.json
index ffb1eea5b65..ac70f434a31 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4854.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4854.json
@@ -1 +1 @@
-{"ABATACEPT": 35.09686344749346, "ADALIMUMAB": 9.193255044639187, "AMINOSALICYLIC": 3.288616115737017, "APREMILAST": 7.089402273940031, "ARAVA": 1.7679042278173362, "BOTULINUM": 10.936227848000453, "CIMZIA": 1.741420127650097, "COSENTYX": 4.289316321982557, "ENTRESTO": 1.941691812095782, "IBRANCE": 2.018537798798818, "PEGASYS": 1.7994322385836838, "PEGINTRON": 2.605827300433849, "SUTENT": 3.3956769905256694, "TOVIAZ": 7.053491848512653}
\ No newline at end of file
+{"CICLOSPORIN": 10.151745560848358, "null": 0.8107925680758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4855.json
index 26e5710db8d..7982e04d4a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4855.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4855.json
@@ -1 +1 @@
-{"ABACAVIR": 8.871796013938816, "AP": 2995.653479617848, "CLOPIDOGREL": 5.809397809441265, "FORTIMEL": 4132.516782492467, "LYRICA": 7.2775840105700675, "PLAVIX": 3.278526683660457, "null": 2.5478623390386144}
\ No newline at end of file
+{"AZATHIOPRINE": 11.050394306188178, "CANCIDAS": 34.02599070962757, "CELLCEPT": 5.541713382971231, "CICLOSPORIN": 3.7151012967561017, "COMIRNATY": 0.3152447094766386, "HUMIRA": 4.564372566058133, "JARDIANCE": 3.6170807592913263, "SPIKEVAX": 0.2019953166039718, "SUTENT": 2.1079193083712373, "ZOSTAVAX": 4.506738692900286, "null": 0.8005828810298574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4856.json
index ab574a10d21..c1bbb4b698c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4856.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4856.json
@@ -1 +1 @@
-{"null": 2.4876892533848878}
\ No newline at end of file
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4857.json
index 420ee7f235d..91acdd4c051 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4857.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4857.json
@@ -1 +1 @@
-{"SUTENT": 3.4663938587292744, "null": 2.001389135307804}
\ No newline at end of file
+{"CICLOSPORIN": 11.203166294349778, "JANUVIA": 17.777012565447045, "null": 1.0036032441389895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4858.json
index e37bf323b02..0d4f33f246b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4858.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4858.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 6.9612232472192535, "null": 1.382675755092757}
\ No newline at end of file
+{"null": 1.4293166421256611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4859.json
index 9a136c64cb8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4859.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4859.json
@@ -1 +1 @@
-{"GARDASIL": 5.0152810186693495, "HUMALOG": 3.503806135454594, "KEPPRA": 3.406737208157162, "METHOTREXATE": 6.198313270573319, "SUTENT": 2.1785697272631683, "TOZINAMERAN": 1.053042803772458, "null": 1.051033988070584}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/486.json
index e2998e36555..7a67dce49cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/486.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/486.json
@@ -1 +1 @@
-{"null": 1.609848241428752}
\ No newline at end of file
+{"null": 0.3410849526528416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4860.json
index aae0c4c05d8..c83c34ab753 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4860.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4860.json
@@ -1 +1 @@
-{"null": 1.2897868525631466}
\ No newline at end of file
+{"ARAVA": 0.8149065534613396, "AUBAGIO": 2.5018435143340563, "CELLCEPT": 2.556727261351347, "CICLOSPORIN": 1.434854920247763, "CIMZIA": 1.6351155878557375, "COMIRNATY": 0.4705059287744431, "COSENTYX": 6.549532920978803, "ENTYVIO": 12.666403558861816, "FORSTEO": 1.335610201590089, "FORXIGA": 2.7785471903872083, "GARDASIL": 0.9102328000312307, "HUMIRA": 4.915432095373986, "INCIVO": 5.748901220733634, "JARDIANCE": 1.5173224363979267, "LANTUS": 0.8642604736725213, "NEXAVAR": 2.9628835777323466, "PEGASYS": 2.5750134696979226, "RINVOQ": 4.965253144851592, "ROACTEMRA": 2.4904993207679382, "SIMPONI": 5.271877572437044, "SPIKEVAX": 0.3584574670831549, "STELARA": 2.07608935107074, "SUTENT": 4.6563117774364695, "TOZINAMERAN": 0.7120421248779742, "VAXZEVRIA": 0.2795183033949962, "VOTRIENT": 2.034606580289052, "XELJANZ": 3.81059626690815, "null": 0.697089286804699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4861.json
index 19abdb1c0be..bf32939581e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4861.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4861.json
@@ -1 +1 @@
-{"ASPARAGINASE": 2.200092581512791, "BRIDION": 3.617718833455508, "BRILIQUE": 1.5252015673946528, "COTELLIC": 4.096246433612609, "EXFORGE": 1.188142216429674, "IBUPROFEN": 3.4243751666264832, "LEVOFLOXACIN": 2.899415331434075, "MICARDIS": 1.5123746057273226, "MIDAZOLAM": 2.599667521392922, "OLYSIO": 3.1115354828713917, "ONCASPAR": 17.640166133587712, "RASILEZ": 2.67879431892859, "null": 4.97136957254804}
\ No newline at end of file
+{"ASPARAGINASE": 23.475407961537847, "BUSULFAN": 34.9964327386839, "CASPOFUNGIN": 178.7844656559994, "CICLOSPORIN": 25.396038339569497, "CLOFARABINE": 322.4011120110772, "CYTARABINE": 28.046526531043806, "DEXAMETHASONE": 11.56229469541203, "GANCICLOVIR": 109.73097073532917, "NOXAFIL": 83.96084495144952, "VORICONAZOLE": 70.60356992255576, "null": 0.0660609724849832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4862.json
index 45c5f9156f8..ade5a105f3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4862.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4862.json
@@ -1 +1 @@
-{"IBRANCE": 2.188061624380058, "SUTENT": 2.814470490632392, "TOZINAMERAN": 1.990172945868432, "null": 1.930901224167665}
\ No newline at end of file
+{"CARFILZOMIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4863.json
index b3a4a501e20..04f8a81ca4f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4863.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4863.json
@@ -1 +1 @@
-{"COMIRNATY": 2.1272476942727536, "MEPOLIZUMAB": 18.598154005894145, "TOZINAMERAN": 1.9050331456446707, "null": 1.5979377595017548}
\ No newline at end of file
+{"OPTIMARK": 3836.558883516212, "null": 0.3246708167090583}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4864.json
index 918b1c5aa16..46548ab395e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4864.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4864.json
@@ -1 +1 @@
-{"APIXABAN": 7.409324600881119, "BETMIGA": 1.9976264548600828, "BEXSERO": 1.9528084245133, "BRIDION": 1.733716368447395, "BYDUREON": 2.115883565434862, "CHAMPIX": 1.015722556296011, "COVID19": 1.225511078750833, "DESLORATADINE": 2.0017512776510054, "ENTRESTO": 4.290892154531568, "EXFORGE": 1.3509030051745927, "FASENRA": 1.305737817390721, "FIASP": 1.6866778164247025, "GALVUS": 1.4008868593847963, "GARDASIL": 1.1192498046547192, "HIZENTRA": 1.00332596266615, "HYDROCORTISONE": 2.785069484812841, "IRBESARTAN": 2.3642070817755774, "MENVEO": 1.4444902352807698, "MICARDIS": 1.3679281066323836, "MMRVAXPRO": 1.1857326038604288, "NIMENRIX": 1.921643945417784, "ONCASPAR": 9.786860654492523, "ONGLYZA": 1.6725414568936698, "OXYBUTYNIN": 2.8199647726728, "PRIVIGEN": 1.1148213429624323, "RASILEZ": 1.9672310175055288, "RELVAR": 1.5236419168470965, "TAMIFLU": 1.592940384019064, "TOUJEO": 1.1265385561255947, "TOVIAZ": 2.36492739717607, "TOZINAMERAN": 2.179975985610524, "XOLAIR": 4.252408121442034, "ZELBORAF": 1.0502671158012598, "null": 2.079295260197871}
\ No newline at end of file
+{"COMIRNATY": 1.0480888795899983, "null": 0.8325331525086475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4865.json
index 1690a45983a..25acfc99461 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4865.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4865.json
@@ -1 +1 @@
-{"AFINITOR": 4.308765376520227, "ARAVA": 3.502370454611716, "CIMZIA": 10.041032503182407, "COSENTYX": 6.169311991799358, "FENTANYL": 5.351134311401888, "METHOTREXATE": 6.239772171286459, "null": 1.0252423479538424}
\ No newline at end of file
+{"ABACAVIR": 0.1842478817651915, "ABASAGLAR": 0.3144753138877034, "ABATACEPT": 0.839485014411954, "ABILIFY": 1.0104671719089564, "ACE": 4.175141021995201, "ACLASTA": 2.7199392187332534, "ACTOS": 0.564520831398848, "ADALIMUMAB": 0.6914082827322213, "ADCIRCA": 0.4700059442832483, "ADEMPAS": 1.116424118605941, "AERIUS": 1.0884889359088477, "AFINITOR": 0.912325373907976, "AIMOVIG": 0.5919738974158152, "ALEMTUZUMAB": 0.7765477273841376, "ALIMTA": 0.2900463407628152, "ALL": 1.2500654405387932, "AMBRISENTAN": 1.1968274659706415, "AMIKACIN": 0.2633891776746027, "AMINOSALICYLIC": 0.1397256499442318, "ANAKINRA": 0.6316152763216258, "ANORO": 0.3812244157197577, "APIDRA": 0.7981110287472065, "APIXABAN": 1.5735041430688212, "APREMILAST": 4.878890505871176, "APROVEL": 0.6988042672072885, "ARANESP": 0.2641393588186436, "ARAVA": 1.9861964563494845, "ARIPIPRAZOLE": 0.9433172142576094, "ASPARAGINASE": 0.2827892447989927, "ATAZANAVIR": 0.2547818531751334, "ATEZOLIZUMAB": 1.2898983737090888, "ATRIPLA": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4866.json
index 93f3ef85214..bc9e04c2304 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4866.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4866.json
@@ -1 +1 @@
-{"JANUVIA": 28.96956336952664, "JARDIANCE": 14.42509155329727}
\ No newline at end of file
+{"ABATACEPT": 5.864223907254919, "ABILIFY": 0.6545439554027864, "ADALIMUMAB": 4.023288057629049, "AFINITOR": 0.2123745294908326, "AIMOVIG": 0.3598913699903288, "AMINOSALICYLIC": 0.6222753818592311, "ANAKINRA": 0.9472170418016956, "APIDRA": 0.8128059881531178, "APIXABAN": 0.8029114195704091, "APREMILAST": 7.760141213654442, "APREPITANT": 1.7680620887107457, "APROVEL": 0.9240493963053124, "ARANESP": 0.2597046784620352, "ARAVA": 2.239598884668879, "ARIPIPRAZOLE": 0.3839344547903381, "ASPARAGINASE": 0.5445301284568244, "ATRIPLA": 0.1815285259313618, "AUBAGIO": 2.9367993127719862, "AVANDIA": 0.6807546487389394, "AVASTIN": 0.3924503097503863, "BENLYSTA": 1.232806335497268, "BETAFERON": 2.088595588605608, "BEVACIZUMAB": 0.4289072129277311, "BEXSERO": 2.209768213881706, "BUDESONIDE": 0.7350317330224857, "BUMETANIDE": 5.126562271467251, "BUPIVACAINE": 3.012404799069607, "BYETTA": 0.3020135361618798, "CELLCEPT": 0.1724485652782275, "CHAMPIX": 0.4093335973642265, "CICLOSPORIN": 0.540803987243719, "CIMZIA": 1.0371682634890458, "CLOPIDOGREL": 0.6315512944448901, "COMIRNATY": 0.3610147272932331, "COMTAN": 3.5663399119569354, "CONTRAST": 3.691080789939184, "COSENTYX": 1.3566563191453802, "CYMBALTA": 1.0524111918492425, "CYTARABINE": 0.2140890243709637, "DEXAMETHASONE": 0.4710836424911925, "DULAGLUTIDE": 2.255597690945153, "DULOXETINE": 1.7000102402771415, "ELIQUIS": 0.8295707157899744, "ENBREL": 3.1116297560662014, "ENTRESTO": 0.5056429003253361, "ENTYVIO": 0.5525025679111331, "ESBRIET": 0.3832322472774668, "ETANERCEPT": 6.249530359631804, "EVENITY": 1.1850155982274493, "EXFORGE": 0.8714566652980178, "EXJADE": 0.3639084482828066, "FAMPRIDINE": 5.978552544820518, "FAMPYRA": 11.160871110785877, "FASENRA": 0.471071157540919, "FASLODEX": 0.7348349415439678, "FENTANYL": 0.8637489343434944, "FIRDAPSE": 3.0748778697231858, "FORSTEO": 1.761479113533215, "FULVESTRANT": 1.474907192543168, "GALVUS": 2.100018584079771, "GARDASIL": 2.527331687040578, "HEPSERA": 1.61685396748361, "HIZENTRA": 1.0284482425420616, "HUMALOG": 2.160987136137645, "HUMIRA": 1.3155914548160703, "IBRANCE": 2.27633059772132, "IBUPROFEN": 0.662828901393512, "INCRUSE": 1.112353912760455, "INFANRIX": 1.046956701034688, "INLYTA": 2.51551395858585, "INSULIN": 0.5964852313531117, "IRESSA": 0.5922354624330287, "JANUMET": 0.751565335252917, "JANUVIA": 0.7032385171611041, "JARDIANCE": 0.430981765459031, "KEPPRA": 0.7070538819472809, "KESIMPTA": 1.308452932925344, "KEYTRUDA": 0.8045757838741054, "LANTUS": 1.518471464244727, "LATUDA": 1.4118137271642892, "LEMTRADA": 0.8650270689782861, "LEVEMIR": 0.655788514446505, "LEVETIRACETAM": 0.3009259649379566, "LEVOFLOXACIN": 1.4014246890855722, "LYRICA": 2.677613666943335, "MEKINIST": 0.7027892172608071, "MELATONIN": 1.5741950621954155, "MEPOLIZUMAB": 2.3020708003487287, "METHOTREXATE": 1.032213530640845, "MIMPARA": 3.216013705819196, "MMRVAXPRO": 0.148476765159637, "MYCOPHENOLATE": 1.0929834890810737, "NAGLAZYME": 1.8341290295205173, "NEULASTA": 0.7530028386574436, "NEXAVAR": 1.7108003304863366, "NIMENRIX": 0.4707865025295662, "NUCALA": 0.5901212380516542, "OCRELIZUMAB": 1.0209115813648393, "OLANZAPINE": 0.2876001630810616, "OMALIZUMAB": 0.9448804355865116, "OPSUMIT": 0.4999136654498307, "OPTIMARK": 4.764938781471843, "PEGASYS": 0.8418511922201987, "PEGINTRON": 0.9180573005777268, "PLAVIX": 1.15945584581523, "PLEGRIDY": 0.884531685188932, "PREVENAR": 1.5324573446540122, "PRIVIGEN": 0.5375809991127989, "REVATIO": 0.8537586002700267, "RINVOQ": 1.387735485968184, "RITUXIMAB": 0.7060163702531801, "ROACTEMRA": 0.2594079378573747, "SHINGRIX": 1.5932505932998566, "SILDENAFIL": 0.6683323883133213, "SIMPONI": 1.0227045309684102, "SOLIRIS": 0.5051672386902482, "SPIKEVAX": 0.4692304253315483, "SPINRAZA": 6.485456111872511, "SPRYCEL": 0.5112053432614501, "STALEVO": 3.887561247038376, "STELARA": 0.674524342483442, "STIVARGA": 1.1464669923362991, "STRIBILD": 0.400891029568409, "SUBOXONE": 0.4483052022388367, "SUTENT": 2.52330984342541, "TAMIFLU": 0.5507923016441202, "TASIGNA": 0.3203801360423207, "TOUJEO": 1.6900102636922618, "TOVIAZ": 0.7265630446634935, "TOZINAMERAN": 1.7753244066172502, "TRELEGY": 0.9771574889727732, "TRULICITY": 0.7795011073130302, "TRUVADA": 0.2548923911924828, "VALSARTAN": 1.715300275003923, "VAXZEVRIA": 0.3095120940566319, "VELTASSA": 0.9617489192608248, "VFEND": 0.357210328699108, "VIAGRA": 0.8756181361830837, "VICTOZA": 0.3989540068038917, "VIMPAT": 1.1992759822415124, "VOTRIENT": 0.8168338839107928, "XALKORI": 1.0304345354862077, "XARELTO": 0.6696049214658771, "XELJANZ": 4.451775321529252, "XOLAIR": 0.6701409107240015, "XTANDI": 2.4856700675003744, "ZOSTAVAX": 0.5537962840563223, "ZYPREXA": 0.4947399003473307, "null": 1.0293412853548232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4867.json
index 3bbe9fe29d5..28076ce93d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4867.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4867.json
@@ -1 +1 @@
-{"ABILIFY": 1.548103764121435, "ADCIRCA": 4.9118258206569845, "AMINOSALICYLIC": 1.7499755429267851, "ASPARAGINASE": 7.399089291530031, "ATAZANAVIR": 1.970052995694224, "AUBAGIO": 1.8309715180598305, "BARACLUDE": 6.024164602347864, "BOSULIF": 4.18589047240673, "BRAFTOVI": 2.835657183522277, "BYDUREON": 7.919849003659774, "BYETTA": 10.136331236647957, "CABOMETYX": 1.8456090319112293, "CELLCEPT": 1.9596983323676869, "COMBIVIR": 3.386938801884705, "CRIXIVAN": 6.302456072497876, "CYTARABINE": 1.6896177187750965, "DASATINIB": 26.601097506718855, "ENTYVIO": 1.2425484134732414, "EPIVIR": 9.724482354172173, "EUCREAS": 67.63168697118317, "EXJADE": 1.8235823809816083, "FORXIGA": 2.7326896554857965, "GALVUS": 26.78752759263563, "HARVONI": 1.4484302061349452, "HYDROCORTISONE": 3.4920478303509577, "ICLUSIG": 22.64525056272141, "INLYTA": 1.3877758081207965, "INOTUZUMAB": 81.7024835845914, "IPILIMUMAB": 4.333568386422847, "ISENTRESS": 4.41054915562292, "JANUMET": 17.04002262383921, "JANUVIA": 17.048021654068837, "JARDIANCE": 2.6615758487331567, "KALETRA": 6.006202476849299, "KEPPRA": 1.3748381263187612, "KEYTRUDA": 2.234355698926608, "MEKINIST": 3.830614050862919, "MERCAPTOPURINE": 7.899123843845635, "MICARDIS": 1.281746738377478, "NEXAVAR": 5.687153491700794, "NILOTINIB": 16.270825269823412, "ONCASPAR": 15.420887004898502, "OPDIVO": 3.2232245572285403, "PEMBROLIZUMAB": 1.4273240263089018, "RYBELSUS": 8.741235794760204, "SAXENDA": 15.057639001971657, "SCEMBLIX": 47.84433307375701, "SPRYCEL": 1.2659965534351596, "STIVARGA": 1.8718600709085924, "SUTENT": 1.3168586618094762, "TASIGNA": 32.00851409859394, "TRULICITY": 27.81706180731476, "VELMETIA": 39.6792820680849, "VICTOZA": 24.9459175265347, "VIREAD": 3.8011608575206366, "VOTRIENT": 2.7873366373119564, "ZIAGEN": 11.904355371471253, "ZYPREXA": 2.1135296053248007}
\ No newline at end of file
+{"IRBESARTAN": 545.6683246105284, "null": 0.7756227871083207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4868.json
index 965b449fd15..7dab0060542 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4868.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4868.json
@@ -1 +1 @@
-{"null": 1.0946308134224956}
\ No newline at end of file
+{"SOMATROPIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4869.json
index f18df8a6df1..6884e48b5d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4869.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4869.json
@@ -1 +1 @@
-{"ABACAVIR": 10.272007388770064, "ATRIPLA": 1.8811432953413276, "BIKTARVY": 57.20426184527183, "COMBIVIR": 24.880789245241147, "ZYPREXA": 8.691064027313393}
\ No newline at end of file
+{"ABILIFY": 7.4604094540903025, "AIMOVIG": 3.777469495971169, "ARIPIPRAZOLE": 4.745979295691932, "BRINTELLIX": 3.7954394802651295, "COMIRNATY": 0.2915325194803457, "CYMBALTA": 1.5924613449274458, "GARDASIL": 0.8859727160868928, "INVEGA": 68.16745256660197, "LATUDA": 11.607195555130296, "OLANZAPINE": 8.439398168021741, "RISPERIDONE": 10.581923308275991, "SPIKEVAX": 0.1287483944913164, "ZYPREXA": 18.076007985334044, "null": 4.225077948777081}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/487.json
index 1287c7931b2..f653e98f2b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/487.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/487.json
@@ -1 +1 @@
-{"GARDASIL": 18.15384972895468, "LEMTRADA": 139.0987784470424}
\ No newline at end of file
+{"OMALIZUMAB": 318.7586976707087, "null": 0.5637527582657493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4870.json
index 0348e1c890e..d655a9ceb93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4870.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4870.json
@@ -1 +1 @@
-{"ARAVA": 1.966917520960484, "CELSENTRI": 97.2135798576956, "CICLOSPORIN": 5.762445574042518, "DESCOVY": 106.53451714813713, "HUMALOG": 2.873277170397168, "KALETRA": 14.103983110461328, "OLANZAPINE": 4.002983003452871, "RINVOQ": 25.13823522661907, "ROACTEMRA": 14.949862124036123, "UPADACITINIB": 105.97899889350984, "XELJANZ": 3.841642055216963, "ZYPREXA": 12.961412966144104}
\ No newline at end of file
+{"ZAVESCA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4871.json
index e0c1dfe747b..610368cd814 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4871.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4871.json
@@ -1 +1 @@
-{"ABACAVIR": 46.42425179826252, "APIDRA": 7.125962489516124, "ATAZANAVIR": 46.76954413248669, "COMBIVIR": 18.59625241056286, "EPIVIR": 190.60670605547568, "HUMALOG": 7.627500257782525, "INDINAVIR": 131.48348004087248, "INSULIN": 23.663757305543054, "KALETRA": 10.605008895367536, "LAMIVUDINE": 43.77061911694503, "LANTUS": 2.372196513705373, "LEVEMIR": 21.88253394069027, "NOVORAPID": 28.799145734600717, "REYATAZ": 72.72424495166167, "STAVUDINE": 502.6771923047401}
\ No newline at end of file
+{"COMIRNATY": 6.06335710414263, "SPIKEVAX": 1.5920001476817427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4872.json
index 8c98b3da53d..4de0aba521a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4872.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4872.json
@@ -1 +1 @@
-{"ABACAVIR": 65.03054498160915, "ABASAGLAR": 8.842062201004781, "ACTRAPID": 18.486994368373526, "AMPRENAVIR": 147.90997635781167, "APIDRA": 16.60002005215803, "APTIVUS": 313.1885069513086, "ATAZANAVIR": 61.83313937217041, "ATRIPLA": 1.5503947557516486, "BIKTARVY": 9.772942216336924, "COMBIVIR": 121.14353686676807, "CRIXIVAN": 118.34258518135223, "EFAVIRENZ": 56.82285513435125, "EMTRICITABINE": 17.559610123437768, "ENFUVIRTIDE": 155.41778268445293, "EPIVIR": 91.77322139930904, "FIASP": 9.927281986718564, "FORTOVASE": 94.48533793058571, "HUMALOG": 1.8945652005091247, "INDINAVIR": 138.6639156308147, "INSULIN": 5.908147386209165, "INTELENCE": 57.52824164423886, "INVIRASE": 107.48170491901207, "ISENTRESS": 43.97566010068277, "KALETRA": 20.463836895459032, "LAMIVUDINE": 23.014576515920773, "LANTUS": 6.803861244929651, "LEVEMIR": 10.242424622805435, "NEVIRAPINE": 30.515514340110848, "NORVIR": 51.442515404716, "NOVORAPID": 5.226307908481054, "REYATAZ": 45.35792210685551, "SAQUINAVIR": 540.0979097647316, "SEMGLEE": 373.8506342293514, "TIVICAY": 16.553652358115084, "TRIUMEQ": 12.824058483691358, "ZERIT": 129.77964585708622}
\ No newline at end of file
+{"BOSENTAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4873.json
index 9925eed10f7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4873.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4873.json
@@ -1 +1 @@
-{"ABACAVIR": 18.16045255675414, "COMIRNATY": 1.6541991188117728}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4874.json
index a81b0114c22..2cfb06ae911 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4874.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4874.json
@@ -1 +1 @@
-{"null": 2.6556073102073143}
\ No newline at end of file
+{"null": 4.188692368715918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4875.json
index e78ce418626..48198e5d56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4875.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4875.json
@@ -1 +1 @@
-{"ATAZANAVIR": 22.06335317116376, "ATRIPLA": 1.034567331070841, "CICLOSPORIN": 3.2624178034770117, "CRIXIVAN": 41.87978178834146, "EFAVIRENZ": 34.48858109831706, "HUMALOG": 5.723343559366875, "INSULIN": 17.42416003861978, "LANTUS": 6.934632441827537, "LEVEMIR": 22.755453490831044, "MEPOLIZUMAB": 10.58935036183204, "NORVIR": 60.87722005330464, "NOVORAPID": 11.228253514148156}
\ No newline at end of file
+{"null": 0.9986656045005448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4876.json
index 7bb1d4475e5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4876.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4876.json
@@ -1 +1 @@
-{"COSENTYX": 4.016182886060782, "ENBREL": 2.512218287165735, "HUMALOG": 2.9311809518849734, "JANUMET": 5.198422199596653, "JANUVIA": 5.697905834059018, "PEGASYS": 1.7210261364840247, "STELARA": 7.266525397216478, "XELJANZ": 1.7613264587026771, "ZOSTAVAX": 4.351657130454828}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4877.json
index 8ec153407f8..5f97310265c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4877.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4877.json
@@ -1 +1 @@
-{"null": 1.3092049495297184}
\ No newline at end of file
+{"TRELEGY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4878.json
index 94bf5b74868..854a231aaba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4878.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4878.json
@@ -1 +1 @@
-{"null": 1.118542882024994}
\ No newline at end of file
+{"null": 0.855331966490197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4879.json
index 68ddb779b3a..c0fb60d3d1f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4879.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4879.json
@@ -1 +1 @@
-{"null": 1.0124475158719186}
\ No newline at end of file
+{"AFINITOR": 2.0745251195486287, "ARAVA": 1.0754395050327776, "AUBAGIO": 1.815864601391104, "BYDUREON": 4.630792689776322, "BYETTA": 8.018638933051415, "CIMZIA": 1.4412550532012962, "COMIRNATY": 0.0685591332586443, "COSENTYX": 0.9746612486792472, "CYMBALTA": 1.0018833839792494, "ELIQUIS": 3.482707659943685, "ENBREL": 1.4244704918799405, "ENTYVIO": 1.445310687601107, "EXFORGE": 1.8071673862453543, "EXJADE": 1.6846798078387946, "GARDASIL": 1.191523874187682, "HUMALOG": 1.8817389233431407, "IBRANCE": 1.6705744991553078, "INLYTA": 2.248766413252454, "JAKAVI": 1.533356940245539, "JANUMET": 6.890985240644676, "JANUVIA": 6.886045928748315, "LANTUS": 3.966729306889741, "OPSUMIT": 2.1531805407849545, "PEGASYS": 0.9271328056830556, "PEGINTRON": 1.871994105302664, "REVATIO": 7.465311595919974, "SAXENDA": 8.285145149548281, "SIMPONI": 1.2916071410611132, "SOLIRIS": 2.3024280036148377, "SPIKEVAX": 0.0615009863993676, "SPRYCEL": 2.766055353890416, "SUBOXONE": 6.179151297682488, "SUTENT": 2.166754055573439, "TOZINAMERAN": 0.1424871679666058, "TRULICITY": 2.369736299881586, "VFEND": 3.3904163348875427, "VIAGRA": 2.3174803065703093, "VICTOZA": 7.830111722130526, "XELJANZ": 2.8332988935768126, "XTANDI": 0.8420159596950392, "ZOSTAVAX": 1.809467210683112, "null": 1.5108592128118812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/488.json
index 4ddd7d28975..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/488.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/488.json
@@ -1 +1 @@
-{"COMIRNATY": 4.343951402358383}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4880.json
index b168aa976b7..59116478074 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4880.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4880.json
@@ -1 +1 @@
-{"ACTRAPHANE": 146.44913670522578, "APIDRA": 7.7358756873391075, "FIASP": 420.4859578835674, "HIZENTRA": 4.500303814138518, "INSULATARD": 75.28688640571029, "LANTUS": 1.643178855368726, "LEVEMIR": 9.255694770450212, "MIXTARD": 46.19583586412519, "MMRVAXPRO": 1.957457002966088, "NEVANAC": 251.35581652330288, "NOVORAPID": 388.0570938410197, "PROTAPHANE": 269.42646882059927, "SAXENDA": 9.349475343780858, "SIMPONI": 1.249040953283327, "STELARA": 5.76983259568185, "TREMFYA": 11.521932700711902, "TRESIBA": 29.878842219642, "VICTOZA": 4.15020206228933}
\ No newline at end of file
+{"COMIRNATY": 0.0877324633642952, "CYTARABINE": 11.8698628159706, "JANUMET": 9.242598129176717, "JANUVIA": 9.142924728060771, "KEYTRUDA": 2.3226943086584, "null": 0.918279144208052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4881.json
index 6d55750d5d7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4881.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4881.json
@@ -1 +1 @@
-{"null": 2.739337169947462}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4882.json
index 1f6d2bb56fa..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4882.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4882.json
@@ -1 +1 @@
-{"LEMTRADA": 131.10689916181974}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4883.json
index ead611013ef..01098349077 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4883.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4883.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 45.08557899441609, "AZATHIOPRINE": 24.7935458554767, "CICLOSPORIN": 6.404523061228796, "LEMTRADA": 79.30399236280809}
\ No newline at end of file
+{"null": 1.2825526105920724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4884.json
index 1f8796a9429..e4079eb49c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4884.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4884.json
@@ -1 +1 @@
-{"BRILIQUE": 1.6601399133053003, "CHAMPIX": 2.2563440532310266, "ELIQUIS": 1.7936491724331085, "ENTYVIO": 1.5847744947911109, "FORSTEO": 1.3521215445715729, "GARDASIL": 1.5635027673721729, "KAFTRIO": 3.142555152760239, "KEPPRA": 1.4336344274511787, "KESIMPTA": 4.753311765503098, "LEVETIRACETAM": 1.1385150811812332, "MMRVAXPRO": 78.48819994934202, "NIMENRIX": 9.401515346152744, "OFEV": 1.6696538114471262, "PLEGRIDY": 3.350489073691868, "ROACTEMRA": 1.1939796802093654, "ROTATEQ": 4.227785841512978, "SHINGRIX": 1.2381954209082826, "TWINRIX": 5.788596026541258, "XTANDI": 1.3882047122990828, "null": 1.0543057760305994}
\ No newline at end of file
+{"null": 0.6328555915525093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4885.json
index eebe04e2bb6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4885.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4885.json
@@ -1 +1 @@
-{"KAFTRIO": 84.97749147897477}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4886.json
index 2d8b025fcb2..f0401afe8dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4886.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4886.json
@@ -1 +1 @@
-{"ABACAVIR": 2.278848749431539, "ABATACEPT": 20.489959678244837, "ABILIFY": 7.838143885716013, "ADALIMUMAB": 6.8740139502629525, "AMINOSALICYLIC": 1.5651007438254327, "ANESTHESIA": 139.48583358761417, "ANTIBIOTICS": 24.482197729375407, "APREMILAST": 28.497321730821493, "ARAVA": 6.834261988394675, "ATAZANAVIR": 6.586866486370775, "AZATHIOPRINE": 24.80128137119303, "BENLYSTA": 3.507425948673032, "BIKTARVY": 6.978214306370388, "BUPIVACAINE": 17.03074081666323, "CELSENTRI": 17.892309315246393, "CERTOLIZUMAB": 35.00823367625806, "COMBIVIR": 17.159039974943088, "DARUNAVIR": 10.06468039475834, "DEXAMETHASONE": 6.5158864372304, "DOLUTEGRAVIR": 10.904616724138082, "ECULIZUMAB": 48.0223760262891, "EFAVIRENZ": 6.079738640431882, "EMTRICITABINE": 5.471324079702918, "ENOXAPARIN": 8.446441254877003, "EPIVIR": 6.587160846630346, "EPOETIN": 21.275077080012537, "FENTANYL": 12.979508841692985, "FONDAPARINUX": 196.14851672721463, "HYDROCORTISONE": 10.80564277732502, "INSULIN": 1.2247403894371507, "INVIRASE": 14.963944881939105, "IRON": 8.036657697663637, "ISENTRESS": 3.944480221883075, "KALETRA": 7.092025400495164, "KIVEXA": 28.074936511916107, "LAMIVUDINE": 6.563415513755155, "LOPINAVIR": 20.073412454885304, "MAVENCLAD": 5.838032820397292, "NORVIR": 25.246827942120824, "OLANZAPINE": 1.0292298025987725, "REYATAZ": 17.04406533358518, "null": 1.0890025308069995}
\ No newline at end of file
+{"null": 0.5234282361212452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4887.json
index b7cd4d34684..89e0c1eb07d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4887.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4887.json
@@ -1 +1 @@
-{"BOSULIF": 22.41480255799906, "CLOPIDOGREL": 1.5589909889252418, "COVID19": 1.0114640782257331, "FLEBOGAMMA": 24.941787286090964, "GARDASIL": 3.2144602592322165, "KIOVIG": 60.54969248978288, "MMRVAXPRO": 1.7551544301499105, "NAGLAZYME": 10.280916975096504, "OPTIMARK": 6.388184635194754, "PRIVIGEN": 19.03912835262059, "VAXZEVRIA": 1.1381294696752478, "null": 1.3910690738702898}
\ No newline at end of file
+{"null": 1.4003020621202162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4888.json
index 4677523169c..c6c36b00639 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4888.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4888.json
@@ -1 +1 @@
-{"AFINITOR": 2.9437723717783646, "AMIKACIN": 15.503320153638995, "ASPARAGINASE": 9.19155590411931, "AVASTIN": 5.37008012130089, "BYETTA": 4.106544327383777, "CELLCEPT": 5.329942300116247, "CICLOSPORIN": 3.845771368460654, "CIMZIA": 1.3479580931431985, "COSENTYX": 2.044992251511394, "CYTARABINE": 5.575072098749756, "DEXAMETHASONE": 2.864475806966906, "ENTYVIO": 4.679804849207558, "JAKAVI": 4.380022929058129, "JARDIANCE": 1.9529402243490188, "KEYTRUDA": 1.850097733425312, "LENVIMA": 13.400039871420544, "NEXAVAR": 10.125482308195616, "RINVOQ": 5.309696110515334, "ROACTEMRA": 8.002409543469943, "SUTENT": 1.9888892588713545}
\ No newline at end of file
+{"null": 0.5283813682031073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4889.json
index 525504158ab..bf5d2fa6942 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4889.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4889.json
@@ -1 +1 @@
-{"LENVIMA": 271.07394042044467, "NEXAVAR": 297.61951492211045}
\ No newline at end of file
+{"BYETTA": 5.221135924767798, "CIMZIA": 2.899247530926276, "ELIQUIS": 1.407496387206264, "FORSTEO": 3.3746376991599685, "IBRANCE": 4.231747137504277, "JANUMET": 6.848272622590489, "JANUVIA": 7.394897326739481, "LANTUS": 5.66741933240526, "SAXENDA": 17.142103989999185, "SIMPONI": 12.6262384910705, "STELARA": 2.9433468964910228, "ZOSTAVAX": 4.415633738620838, "null": 1.46766679224901}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/489.json
index cbfdf1fda37..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/489.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/489.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 24.57803533114699, "GARDASIL": 4.171913179417255, "LEMTRADA": 314.36001348904705, "PEGASYS": 3.157985364535693, "PEGINTRON": 7.516104243376881}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4890.json
index 2000b8a6b09..48523bda10a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4890.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4890.json
@@ -1 +1 @@
-{"ABATACEPT": 1.339913070830458, "ABRAXANE": 2.642989716356119, "ACTOS": 3.548193830579446, "ADALIMUMAB": 1.6970104853822376, "ADCIRCA": 3.237375237492586, "AFINITOR": 1.1349648354415025, "ALIMTA": 2.3133165310214348, "AMINOSALICYLIC": 1.8820875311590155, "APREPITANT": 1.0927552817728328, "ARAVA": 1.1939118675002398, "ASPARAGINASE": 1.9241326289999523, "AUBAGIO": 1.2449546576420742, "AVASTIN": 1.238946231852346, "AXITINIB": 3.3729178115512246, "BARACLUDE": 8.605807127052278, "BAVENCIO": 4.64996926001087, "BETAFERON": 1.541124671731404, "BEVACIZUMAB": 1.0302231313736012, "BINIMETINIB": 8.394019310031123, "BLINCYTO": 4.078308777820453, "BORTEZOMIB": 2.8775596145840594, "BOSULIF": 3.7584599413202393, "BOTULINUM": 1.1768631632604103, "BRAFTOVI": 4.004724307976833, "CABOMETYX": 6.030318712884438, "CANCIDAS": 4.661810132107933, "CAPECITABINE": 1.7756303241912983, "CARFILZOMIB": 1.2065218509353586, "CELECOXIB": 1.486718053082482, "CELLCEPT": 1.3234768317154162, "CICLOSPORIN": 1.0049595142186345, "COMTAN": 1.4723359401302716, "COSENTYX": 1.4995883250716555, "COTELLIC": 1.436940168440707, "CUBICIN": 1.015879094566413, "DAKLINZA": 2.1047147619145083, "EDURANT": 7.24168984015721, "EFIENT": 2.002261408379223, "ELIQUIS": 1.057548066776999, "EMEND": 1.4751841880686496, "ENBREL": 4.627624697476847, "ENTYVIO": 1.388337954378177, "EPCLUSA": 2.227469251051033, "EPIVIR": 1.6686659168102806, "ESMYA": 2.5057395282185007, "EXFORGE": 1.09699548055979, "EXJADE": 4.537421315914231, "FASLODEX": 1.4563689601071306, "FEBUXOSTAT": 6.650367268911463, "GALVUS": 1.7347385982880577, "GANCICLOVIR": 2.380944135646563, "GLIVEC": 2.751413058219708, "HALAVEN": 1.7022832695638312, "HARVONI": 1.399094178355062, "HEPSERA": 2.052152721024981, "HUMALOG": 1.1178766727587968, "IBRANCE": 1.145725845528977, "IBUPROFEN": 1.1381334856350802, "ICLUSIG": 2.3031826408148737, "IMFINZI": 10.704866227543205, "INCIVO": 1.4404434807160411, "INLYTA": 1.959803153520072, "IPILIMUMAB": 1.9115081421592848, "IRESSA": 12.835000063960898, "ISENTRESS": 3.51379628327106, "JAKAVI": 1.1811878495180292, "JANUVIA": 1.7994640123007957, "KAFTRIO": 1.9946505279577091, "KALETRA": 1.3812371173579976, "KEYTRUDA": 3.477080683953705, "KISQALI": 1.9825865896222543, "KYPROLIS": 1.9454839609606047, "LAMIVUDINE": 1.1209029017328909, "LEFLUNOMIDE": 1.1266135292165478, "LENVIMA": 4.174418119128023, "LEVOFLOXACIN": 1.4617496339332825, "LONSURF": 1.5061336906412708, "LYNPARZA": 1.2728550263584255, "LYRICA": 1.846774463387824, "MEKINIST": 2.676789269560892, "METHOTREXATE": 1.892532330833978, "MICARDIS": 6.399679187593398, "MIRCERA": 1.1024200940083764, "MULTAQ": 1.3259093592694835, "NEXAVAR": 4.91871587189219, "NIVOLUMAB": 3.7817380314767433, "NORVIR": 1.2340123395566758, "NOT": 1.7982439540780055, "NOVONORM": 1.578627704850836, "NOXAFIL": 1.48033085250778, "OCALIVA": 2.315184593772416, "OFEV": 2.3109187802046227, "ONCASPAR": 2.8780958641495054, "OPDIVO": 11.26697223504703, "OPSUMIT": 1.0319124252975227, "PAZOPANIB": 1.3094364914635066, "PEGASYS": 1.113516846320555, "PEGINTERFERON": 1.4716979445635925, "PEGINTRON": 1.2899112496186935, "PLAVIX": 1.846157784558877, "POTELIGEO": 4.941759699053839, "RAPAMUNE": 1.6884296890802963, "REBETOL": 2.515200901213209, "REMDESIVIR": 2.712353451945241, "REMICADE": 1.6829572745182406, "REVATIO": 1.11341483219222, "REVLIMID": 1.1531960207884853, "REVOLADE": 5.854211892527528, "RIBAVIRIN": 1.3808603126284122, "RIBOCICLIB": 1.582642326720804, "RINVOQ": 1.4757300907840138, "SAMSCA": 4.238596509568318, "SIMPONI": 1.5193911113002798, "SOTORASIB": 6.937692081216955, "SOVALDI": 1.1432877208122243, "STIVARGA": 6.031307863881112, "SUTENT": 1.400324967287219, "TACROLIMUS": 1.4410897421089426, "TAGRISSO": 3.2453349166959704, "TAMIFLU": 5.3958315552922365, "TASIGNA": 2.637982610648082, "TEMODAL": 2.0105244928308434, "TRACLEER": 1.5881357893488832, "VEKLURY": 6.838037003637965, "VFEND": 7.066124976710237, "VIMPAT": 1.1878368438236775, "VORICONAZOLE": 1.9080377463071252, "VOTRIENT": 2.061150486334104, "XALKORI": 2.6982119486132814, "XARELTO": 1.5356888447870485, "XELJANZ": 1.3393079606430252, "YERVOY": 2.1825646687641305, "ZYPREXA": 1.0522447995746758, "null": 1.5424968741567324}
\ No newline at end of file
+{"COMIRNATY": 0.1434142327822194, "PEGASYS": 3.80025163421434, "null": 1.51301184072387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4891.json
index 118ff1610d5..b1614825c64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4891.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4891.json
@@ -1 +1 @@
-{"ACLASTA": 12.716323075861728, "ADENURIC": 2.564100772432423, "AMIKACIN": 1.2921415691267455, "ANAKINRA": 1.901820511581315, "ARAVA": 1.5492004024139303, "ASPARAGINASE": 1.7955421843890538, "ATAZANAVIR": 1.2506056628708413, "AVANDIA": 1.3026408234303477, "AZACITIDINE": 1.8689779212757192, "AZATHIOPRINE": 5.157451865912398, "BETAFERON": 1.0886264118175075, "BOSULIF": 1.6498535697880354, "CABOMETYX": 1.2280393976803363, "CANCIDAS": 3.136483807733892, "CANNABIDIOL": 4.77127703389505, "CASPOFUNGIN": 2.9071983011082634, "CELECOXIB": 2.0804162203060703, "CELLCEPT": 2.712470878928291, "CICLOSPORIN": 1.9630393283171397, "COAPROVEL": 1.261638124179118, "COMBIVIR": 5.160906144476018, "COMTESS": 12.673551314986488, "CUBICIN": 1.1241702614296372, "DACLIZUMAB": 88.08209458992357, "DENOSUMAB": 15.638355665605555, "DEXAMETHASONE": 1.286740580615492, "EFAVIRENZ": 2.119238086866003, "EMTRIVA": 5.552062979442419, "ENBREL": 1.700575009142346, "ESMYA": 5.086456913606974, "EXJADE": 2.604317477218185, "FEBUXOSTAT": 6.175604854779799, "GALVUS": 2.3870294615828054, "GAZYVARO": 2.197509857588608, "GEFITINIB": 5.501414530026557, "HUMIRA": 2.5244614658908384, "HYDROCHLOROTHIAZIDE": 3.499071064472354, "IBUPROFEN": 1.5776508796626207, "INVIRASE": 5.967640076123396, "IPILIMUMAB": 1.0029713752303502, "IRESSA": 2.463257788588159, "KAFTRIO": 2.5349645074168983, "KALETRA": 4.857936210709581, "KEPPRA": 1.7831137208037255, "KISQALI": 4.145631872372797, "LAMIVUDINE": 3.989939901651817, "LEVETIRACETAM": 1.805027327717869, "LEVOFLOXACIN": 1.454861221845297, "LIXIANA": 1.4703176799205286, "MERCAPTOPURINE": 4.525445890859405, "METHOTREXATE": 1.416269834073839, "MICARDIS": 1.805387398407956, "MULTAQ": 5.79210362936562, "NEVIRAPINE": 3.90455602302544, "NEXAVAR": 1.1044556642210357, "NOXAFIL": 1.7310998576653067, "OCALIVA": 1.8755326691950704, "OFEV": 2.7050995841816503, "OLANZAPINE": 2.0787003756372027, "PAZOPANIB": 2.583598603221104, "PLEGRIDY": 1.3566884176861678, "RAPAMUNE": 1.5108894299094475, "REMDESIVIR": 5.731896059626332, "REYATAZ": 2.58293801683463, "RUBRACA": 3.320690882441154, "STELARA": 1.892413811296947, "STIVARGA": 2.787069006118719, "TAMIFLU": 3.129344253175592, "TASIGNA": 1.6072553966724703, "TEMODAL": 1.922688108595045, "TEMOZOLOMIDE": 1.8928301156633476, "TIGECYCLINE": 10.803848506217888, "TIVICAY": 2.8860344175572226, "TRACLEER": 26.956228721887456, "TREMFYA": 5.194483329246184, "TRODELVY": 1.5715015534122505, "TWINRIX": 1.2893227019789295, "VEKLURY": 2.9021044936551323, "VFEND": 11.760859097941418, "VICTOZA": 1.1877309468022816, "VIRAMUNE": 16.01907328745246, "VORICONAZOLE": 4.9609106261429785, "VOTRIENT": 3.0682278115770854, "XALKORI": 2.4478917049008104, "XARELTO": 1.1444035341424394, "ZIAGEN": 4.63103788702584, "ZYPREXA": 1.7267353922467163, "null": 1.8190137742704588}
\ No newline at end of file
+{"null": 0.7841781133378859}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4892.json
index 3e9cde59b44..118a40921d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4892.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4892.json
@@ -1 +1 @@
-{"ABATACEPT": 7.513354477643465, "ADALIMUMAB": 3.2086332847359973, "AFINITOR": 2.051059716885652, "AMINOSALICYLIC": 1.933538733351928, "ARAVA": 2.9102686130140705, "AUBAGIO": 4.520380219892439, "AXITINIB": 4.287770032955797, "AZATHIOPRINE": 7.461416820425723, "BETAFERON": 10.74301469681734, "BIKTARVY": 3.3178096774942105, "BOSULIF": 4.26626372062178, "BRAFTOVI": 1.4622353162045971, "BUDESONIDE": 4.607044378644615, "CABOMETYX": 3.3861393973201386, "CANCIDAS": 1.8741858944032597, "CASPOFUNGIN": 3.473224613704249, "CELLCEPT": 1.349311299502994, "CIMZIA": 2.989521300876958, "COSENTYX": 3.012499009497676, "COTELLIC": 2.334919296695529, "CUBICIN": 3.858283927757722, "DABRAFENIB": 2.319048612076317, "ELIQUIS": 1.4114777704540815, "ENBREL": 2.021581926342047, "ENTYVIO": 1.3800276431607283, "ESBRIET": 2.214722562796281, "ESMYA": 6.076845977151445, "EXFORGE": 1.0107982810815233, "EXJADE": 6.715562055717308, "FAMPYRA": 2.212883192758298, "FASLODEX": 1.941540519246187, "FULVESTRANT": 1.319498383665843, "HERCEPTIN": 1.8052033970663293, "HUMIRA": 1.4353993688047837, "ICLUSIG": 2.1667793031086, "INLYTA": 2.2025627045203127, "IPILIMUMAB": 1.320130533583237, "IRESSA": 2.6305809497949, "ISENTRESS": 2.995057419059889, "JAKAVI": 1.096129000255744, "KAFTRIO": 9.759204938114392, "KEPPRA": 2.1936848038861623, "KESIMPTA": 2.489360719050035, "KEYTRUDA": 1.6353488015566784, "KISQALI": 15.37090083488622, "LEMTRADA": 2.0608254237839514, "LIXIANA": 3.2074843020773915, "LONSURF": 1.254962094191819, "MEKINIST": 4.3246056087454114, "METHOTREXATE": 1.8943763047877051, "MICARDIS": 1.6440811103721926, "MULTAQ": 6.135229458683927, "NEXAVAR": 3.1704099325642408, "NOXAFIL": 4.335560642673161, "OCALIVA": 4.70692040957297, "OFEV": 9.71141303055552, "OLANZAPINE": 1.264167793218891, "OPDIVO": 1.530819574013149, "OPSUMIT": 1.870396745137824, "ORKAMBI": 4.7155056174303445, "PACLITAXEL": 1.6420495009959404, "PAZOPANIB": 4.620312609536337, "PLEGRIDY": 9.298335340278353, "REMDESIVIR": 41.2207836061092, "RIBOCICLIB": 3.722892574065247, "RINVOQ": 3.485373640472775, "ROACTEMRA": 5.080413656551617, "RUBRACA": 6.4920965469468825, "SAXENDA": 2.0251056417235325, "SOTORASIB": 17.2586945444678, "STIVARGA": 4.644175037317708, "SUTENT": 1.4190169722328865, "TAMIFLU": 1.7208097367189543, "TASIGNA": 2.099874599126551, "TEMODAL": 1.6894280339706815, "TIVICAY": 3.2125968792793502, "TRACLEER": 19.71060452045376, "TREMFYA": 1.9638153738905373, "TRESIBA": 2.782408170438118, "TRIUMEQ": 2.785495652725661, "VEKLURY": 6.350322093652966, "VEMLIDY": 10.802338272128758, "VFEND": 8.88344458378139, "VICTOZA": 1.0826534006615465, "VIRAMUNE": 6.119552773167825, "VORICONAZOLE": 3.532889541110577, "VOTRIENT": 7.917242524667291, "XALKORI": 6.77451798307465, "XELJANZ": 1.369487461510439, "YERVOY": 3.66705152791576, "ZELBORAF": 3.3542046490974595, "ZINBRYTA": 16.158964072406498, "ZYPREXA": 1.7359711577012793}
\ No newline at end of file
+{"SIFROL": 231.20483300422177, "null": 2.292584725562504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4893.json
index 10c793ac74e..73df311e064 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4893.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4893.json
@@ -1 +1 @@
-{"ABATACEPT": 6.237150576884588, "ACTOS": 4.949751787472818, "ADALIMUMAB": 8.72996719719374, "AMIKACIN": 1.2511962659013365, "AMINOSALICYLIC": 1.549650533097691, "ANAKINRA": 1.2282328318481566, "APREMILAST": 5.634168981451155, "ARAVA": 6.35759750154798, "ARIXTRA": 3.9336780650627032, "ASPARAGINASE": 1.0371401946045842, "AUBAGIO": 1.2192719565330592, "AVANDAMET": 1.5059451165366955, "AVANDIA": 1.9209611472494923, "AXITINIB": 2.7818436503589345, "BARACLUDE": 3.5877528418912026, "BIKTARVY": 1.3867670845204323, "BOSULIF": 1.333314308886114, "BOTULINUM": 1.8142244795916276, "BUPRENORPHINE": 1.4036346732841047, "BUSULFAN": 1.038455190863306, "CAELYX": 1.6160313330802951, "CANCIDAS": 4.526709125891083, "CAPECITABINE": 2.124449539747236, "CASPOFUNGIN": 1.8144461330726904, "CERTOLIZUMAB": 10.907271545275607, "CICLOSPORIN": 1.03042728336292, "CLOPIDOGREL": 1.2140529474835269, "COSENTYX": 1.922082514308818, "COTELLIC": 1.6690494557369393, "CUBICIN": 1.2058275060843904, "CYTARABINE": 1.4080381757243132, "DAPAGLIFLOZIN": 4.863044443465836, "DEXAMETHASONE": 1.116022089877049, "DOCETAXEL": 1.704420697876035, "DOLUTEGRAVIR": 3.84765355622666, "DOXORUBICIN": 1.854547568785209, "EFAVIRENZ": 2.867689370019945, "EMEND": 3.6608881760268086, "ENOXAPARIN": 4.526313169693091, "ESOMEPRAZOLE": 1.881361200249277, "FEBUXOSTAT": 5.979765053244534, "FULVESTRANT": 1.2519072224339185, "FYCOMPA": 3.229319690224901, "GEFITINIB": 5.327021095731904, "GLIBENCLAMIDE": 2.981297510437962, "HERCEPTIN": 1.044708118625108, "HYDROCORTISONE": 1.20591593503876, "IBUPROFEN": 3.16786042811094, "IRESSA": 1.5259568119454698, "ISENTRESS": 2.133136484320288, "KALETRA": 1.652589241319157, "KEPPRA": 1.2917965652220589, "KINERET": 21.972363966381543, "LAMIVUDINE": 5.951574222691468, "LEVETIRACETAM": 1.620109984293745, "LEVOFLOXACIN": 3.259464455551239, "LOPINAVIR": 5.1131599920309325, "METHOTREXATE": 1.5432025071432394, "MULTAQ": 3.457507176451214, "MYCOPHENOLATE": 1.144477494357388, "NORVIR": 1.2811493954148827, "NOXAFIL": 5.327940108793181, "OLANZAPINE": 1.6589110245184522, "PACLITAXEL": 3.0279507347302164, "PANTOPRAZOLE": 1.2040370005461845, "PAZOPANIB": 3.2495188569297917, "PEMBROLIZUMAB": 1.252370232750696, "PEMETREXED": 2.278333507171818, "REBIF": 8.366328612052788, "REMICADE": 1.1511352423339805, "RIBAVIRIN": 1.5706015332744443, "RIBOCICLIB": 2.180673050781036, "RITUXIMAB": 1.7046029939178888, "SIRTURO": 12.052242875590746, "STIVARGA": 2.698425874431802, "STOCRIN": 11.968814558743084, "TEMODAL": 2.0623628003677035, "TEMOZOLOMIDE": 2.825557141379093, "TICAGRELOR": 1.3725366759575208, "TIGECYCLINE": 10.461446568340955, "TRACLEER": 1.143704399010068, "VFEND": 5.682750917640966, "VORICONAZOLE": 14.16604469093819, "VOTRIENT": 1.7976308245629615, "XALKORI": 2.6201608926682707, "XELODA": 2.1875435848493927, "ZYPREXA": 1.0510724836929486, "null": 1.5651095498625247}
\ No newline at end of file
+{"ABILIFY": 26.894774191108105, "ARIPIPRAZOLE": 9.530642884449946, "AZILECT": 148.12390542308947, "CARBIDOPA": 55.97581084541248, "ENTACAPONE": 151.69592192483438, "LEVODOPA": 254.79365735789688, "SIFROL": 821.3678350455043, "STALEVO": 38.28915995569985, "null": 1.942863774889652}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4894.json
index 722dd83bc3d..b1863136977 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4894.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4894.json
@@ -1 +1 @@
-{"null": 1.1892535402764817}
\ No newline at end of file
+{"ADCIRCA": 212.78407609137832, "null": 1.3238674455015131}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4895.json
index 4e057fc7f08..4ee67547d88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4895.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4895.json
@@ -1 +1 @@
-{"null": 3.215202769711489}
\ No newline at end of file
+{"ELIQUIS": 3.932193412599977, "KEYTRUDA": 4.863051866913594, "OBETICHOLIC": 1002.8322798423314, "OCALIVA": 239.1050901814988, "null": 0.6508724336444767}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4896.json
index 54d684df5a9..3028528f656 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4896.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4896.json
@@ -1 +1 @@
-{"PEGASYS": 4.323495871313302, "null": 1.0435353624732868}
\ No newline at end of file
+{"COMIRNATY": 0.9321873061151504, "null": 0.5983845148152901}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4897.json
index 0e25cf28a40..04de2799543 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4897.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4897.json
@@ -1 +1 @@
-{"BARACLUDE": 43.0860132100201, "CICLOSPORIN": 2.644481403947702, "DACLATASVIR": 131.16569623171617, "DAKLINZA": 50.61370761165082, "EPCLUSA": 57.531365047012585, "HARVONI": 40.72665666149275, "INCIVO": 19.206452201029723, "KAFTRIO": 14.72189004861564, "LANTUS": 2.5500822025690746, "OCALIVA": 62.27696103920935, "OLYSIO": 19.22634199254209, "OPSUMIT": 12.583385700327966, "PEGASYS": 2.4687698225527845, "PEGINTERFERON": 9.091632786840236, "PEGINTRON": 6.172533444558133, "RAPAMUNE": 18.514104413007264, "RIBAVIRIN": 23.68568270437797}
\ No newline at end of file
+{"ABACAVIR": 1.6649907278158111, "ABILIFY": 0.5153318759383944, "ACTOS": 4.157908084253837, "ADENURIC": 2.231576725178692, "AFINITOR": 1.3143722349472502, "ALIMTA": 1.7072224248051522, "AMIKACIN": 3.0065535079785235, "AMINOSALICYLIC": 1.4614779165566791, "ANAKINRA": 1.432453618013983, "APIDRA": 0.6922461861394249, "APREPITANT": 0.7269334759844001, "APROVEL": 3.5162151285545478, "ARAVA": 0.415144508425355, "ARIPIPRAZOLE": 0.7476400812021764, "ARIXTRA": 3.6155011095293967, "ASPARAGINASE": 1.145682032842511, "ATAZANAVIR": 0.9519945351391108, "ATRIPLA": 0.0429491639548271, "AUBAGIO": 3.8438086754690577, "AVANDIA": 1.0994501664983896, "AVASTIN": 0.4253404794009153, "AZATHIOPRINE": 1.2203507009521584, "BARACLUDE": 4.92038040648754, "BEDAQUILINE": 1.1826034318127208, "BETAFERON": 8.029269148548016, "BEVACIZUMAB": 0.9000438694592358, "BIKTARVY": 0.4746472924404407, "BONVIVA": 1.0611815454456086, "BRAFTOVI": 1.3640768468879352, "BRILIQUE": 0.8015648971360082, "BRINTELLIX": 0.3379915513926108, "BUDESONIDE": 0.1396659880030753, "BUSILVEX": 3.423438738546759, "BUSULFAN": 0.4230730346787864, "BYETTA": 0.3870019774377545, "CABOMETYX": 0.4552758755605547, "CAELYX": 1.5715457020425676, "CANCIDAS": 9.246756972660862, "CAPECITABINE": 0.920931652667656, "CASPOFUNGIN": 2.0420539005657545, "CELLCEPT": 1.4775028972141433, "CELSENTRI": 5.677064344594642, "CHAMPIX": 0.7188404881478705, "CICLOSPORIN": 0.9328096089922256, "CIMZIA": 0.1171715640418749, "CLOPIDOGREL": 0.304544511577984, "COAPROVEL": 0.9809585407833592, "COBIMETINIB": 3.527311734242254, "COMBIVIR": 1.6218416852792965, "COMIRNATY": 0.0774192234500237, "COMPLEMENT": 16.21460878059043, "COMTAN": 2.878456788201641, "COSENTYX": 1.0919173848092043, "COTELLIC": 2.860585250027473, "CRESEMBA": 5.037255494651044, "CRIXIVAN": 3.876819013571757, "CUBICIN": 0.9609590303067996, "CYMBALTA": 1.4442198390743648, "CYTARABINE": 1.1538854208021465, "DACLATASVIR": 4.354495610237676, "DASATINIB": 3.001164960339424, "DELAMANID": 9.24921827736326, "DENOSUMAB": 2.874228615359094, "DEXAMETHASONE": 0.3549099007684128, "DOCETAXEL": 0.5560705883533048, "EBIXA": 3.5665522441535016, "EFAVIRENZ": 1.605070204223319, "ELIQUIS": 1.7422391903915937, "EMTRICITABINE": 1.5326885518801514, "ENOXAPARIN": 0.7749919152913582, "ENTRESTO": 1.2166543978896127, "EPIVIR": 6.249540266558678, "ERLEADA": 1.073384297575979, "ESBRIET": 1.6306404561226662, "ESMYA": 14.908905864081284, "ESOMEPRAZOLE": 2.4264874459659787, "EUCREAS": 8.70891737749009, "EXFORGE": 1.2270065586725976, "EXJADE": 1.6466109305413197, "FASLODEX": 0.9004985911262031, "FENTANYL": 0.3577752064740634, "FORSTEO": 0.6205909807380466, "FORXIGA": 0.3537006709792492, "FULVESTRANT": 1.2172023071846096, "GALVUS": 8.287586051827768, "GAZYVARO": 1.9556767284942853, "GILENYA": 5.714944132661755, "GLIVEC": 2.202234744166533, "HALAVEN": 1.2272842509480208, "HEPSERA": 1.767094278908219, "HUMIRA": 0.5316531088899312, "IBRANCE": 0.1938442148883052, "IBUPROFEN": 0.529933934805294, "ICLUSIG": 1.7047702188254057, "INCIVO": 0.6431702460575635, "INLYTA": 0.4166685528728034, "INSULATARD": 5.082973939784116, "INVIRASE": 3.3824270447191336, "IRBESARTAN": 1.6252457728320058, "IRESSA": 0.8406500013467625, "IRINOTECAN": 0.7107284262298252, "ISENTRESS": 1.2126798885501562, "JAKAVI": 2.019385055193068, "JANUMET": 1.4919611215311912, "JANUVIA": 1.140787135030928, "JARDIANCE": 0.4252132530557335, "JEVTANA": 1.0934963726492364, "KAFTRIO": 4.9716898071290405, "KALETRA": 2.51512850260092, "KEPPRA": 2.1876871319357667, "KESIMPTA": 1.5708990422585842, "KEYTRUDA": 0.8171325107738138, "KISQALI": 4.02842079859986, "KIVEXA": 4.525833059178416, "LAMIVUDINE": 2.071123211880536, "LANTUS": 0.0728550641949592, "LEMTRADA": 1.8964732715745436, "LEVETIRACETAM": 0.722259269851328, "LEVOFLOXACIN": 1.1105790535007956, "LIXIANA": 4.238830062019366, "LYRICA": 0.7621002645729364, "LYSODREN": 12.242512024210331, "MANNITOL": 5.852570473464167, "MAVENCLAD": 4.941962076264789, "MEKINIST": 1.7039352897584523, "METHOTREXATE": 0.7241940190352422, "MICARDIS": 2.347468052127309, "MIDAZOLAM": 0.697273507458917, "MIMPARA": 1.3332901566010942, "MULTAQ": 13.096070626026156, "NEXAVAR": 1.6878130422257671, "NORVIR": 1.7311625214887991, "NOVONORM": 3.979566684953581, "NOXAFIL": 5.3613844045880565, "OCALIVA": 6.577725107121158, "OFEV": 4.293371678104928, "OLANZAPINE": 1.9972954489751604, "OLYSIO": 0.8701128657816153, "OPDIVO": 0.5018447218679165, "OPSUMIT": 0.7239296747001958, "ORKAMBI": 1.6392008882508833, "PANTOPRAZOLE": 1.5521887398921803, "PEGASYS": 1.1865074374006297, "PEGINTERFERON": 1.6938935292548585, "PEGINTRON": 0.327757374328632, "PEMBROLIZUMAB": 0.6898726941821275, "PLAVIX": 1.406247294285591, "PLEGRIDY": 2.384532037172422, "PRADAXA": 1.4442169866067611, "PREGABALIN": 0.7991371831937139, "PROTELOS": 5.077490286593045, "RASILEZ": 3.882335517987928, "REYATAZ": 2.030095205158305, "RIBOCICLIB": 3.1493419256252144, "RINVOQ": 1.4636691241745874, "RITUXIMAB": 0.232796007273171, "ROACTEMRA": 2.728626060531597, "SAXENDA": 0.7852370387175415, "SIMPONI": 0.1500106318490993, "SOLIRIS": 0.3016984345887676, "SPIKEVAX": 0.0220073298974769, "STALEVO": 0.945254102340526, "STELARA": 0.4852228637858864, "STIVARGA": 1.2045503567577525, "STOCRIN": 13.98440149259873, "SUSTIVA": 14.588066774648752, "SUTENT": 0.4847135596194436, "TAGRISSO": 0.6342118544959247, "TAMIFLU": 0.8877280395941298, "TASIGNA": 2.207886265208566, "TEMODAL": 3.189726350476666, "TOVIAZ": 0.4650625216118861, "TOZINAMERAN": 0.0174984961566192, "TRACLEER": 8.540162960316653, "TREMFYA": 2.576649240824072, "TRULICITY": 1.0031734025374022, "TRUVADA": 0.1295967929784502, "TWINRIX": 3.58346641813296, "VALDOXAN": 10.651416251477333, "VAXZEVRIA": 0.0122468345207651, "VEKLURY": 5.184415482598313, "VENCLYXTO": 1.5998372816400326, "VFEND": 13.004802692565416, "VIAGRA": 0.4527144463450213, "VICTOZA": 0.7330890089633311, "VIMPAT": 0.7600605867105242, "VIRAMUNE": 8.272662946028708, "VORICONAZOLE": 4.5742565337314405, "VOTRIENT": 1.9677678015157976, "XALKORI": 1.2752268661823356, "XARELTO": 1.1753781245328496, "XELJANZ": 0.235790085331927, "XOLAIR": 0.2552257584341815, "XTANDI": 0.2768964112832157, "YONDELIS": 6.669493541020436, "ZELBORAF": 2.8100449585369094, "ZINBRYTA": 6.332316417040714, "ZYPREXA": 4.241921089613284, "null": 2.221470831509428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4898.json
index 4711e9e44a5..f0401afe8dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4898.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4898.json
@@ -1 +1 @@
-{"PEGINTERFERON": 216.20921605597152}
\ No newline at end of file
+{"null": 0.5234282361212452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4899.json
index 43a2b9f8fa3..2900afdd575 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4899.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4899.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 15.425809834275736, "BASILIXIMAB": 49.61194538204336, "CELLCEPT": 29.554386484103908, "CICLOSPORIN": 78.19263660444946, "MYCOPHENOLATE": 37.03336670706999, "PEGASYS": 3.294369690463115, "PEGINTERFERON": 13.699027567553191, "PEGINTRON": 6.073202179948938, "RAPAMUNE": 63.632980704996754, "RIBAVIRIN": 12.654757578857504, "SIROLIMUS": 340.61135450972023, "TACROLIMUS": 108.23083641779152}
\ No newline at end of file
+{"ALISKIREN": 201.48327063640147, "ATRIPLA": 0.2264750324423447, "COMIRNATY": 0.0544768681743566, "ELIQUIS": 1.6748999624001977, "FORXIGA": 6.245357806954813, "HUMALOG": 9.006841849053604, "INSULIN": 6.016234019801332, "INVOKANA": 117.15922691018568, "JANUMET": 1.8088602174385715, "JARDIANCE": 17.592818231283392, "LANTUS": 5.498441057008426, "LEVEMIR": 5.5318455819178665, "MIXTARD": 31.619309296179427, "NEXAVAR": 1.0278529861575196, "OPTIMARK": 3.024234135694025, "PLAVIX": 1.176687334152042, "ROACTEMRA": 2.341077561302919, "SIMPONI": 1.3733353874568883, "SUTENT": 1.1788480347934618, "TASIGNA": 13.01497844242736, "TRACLEER": 3.409082278858314, "VAXZEVRIA": 0.0500889449296162, "null": 1.1131073276606904}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/49.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/49.json
index 5e448dc46e4..a7d19e295b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/49.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/49.json
@@ -1 +1 @@
-{"CIMZIA": 2.2379192954486182, "COMBIVIR": 15.92037670770376, "GARDASIL": 3.5810030082947564, "KEPPRA": 2.200638191502839, "TAMIFLU": 5.87576722310144, "null": 1.7230363193987783}
\ No newline at end of file
+{"ELIQUIS": 6.589920302667124, "ENOXAPARIN": 72.07732639141402, "null": 1.4651809233323585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/490.json
index 664bbfb8775..263bf947daa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/490.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/490.json
@@ -1 +1 @@
-{"null": 1.4255256721462233}
\ No newline at end of file
+{"ANAKINRA": 133.8890029182049, "CICLOSPORIN": 23.60704785949264, "JAKAVI": 60.09298710381449, "null": 0.2909693343743713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4900.json
index 7cf430accca..ba50e53e4ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4900.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4900.json
@@ -1 +1 @@
-{"COMIRNATY": 1.264654280539471, "FORSTEO": 14.421763753569222}
\ No newline at end of file
+{"MIXTARD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4901.json
index 2c0f35938a9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4901.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4901.json
@@ -1 +1 @@
-{"VOTRIENT": 21.713913861893857, "null": 1.951020859108989}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4902.json
index 50694133ff6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4902.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4902.json
@@ -1 +1 @@
-{"null": 1.8059144093544437}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4903.json
index 2d24d9c1610..c1bbb4b698c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4903.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4903.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3415661888751484, "null": 1.1927577248925028}
\ No newline at end of file
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4904.json
index f37f82d59af..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4904.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4904.json
@@ -1 +1 @@
-{"BUPIVACAINE": 595.3668374268615, "null": 3.0624739922083037}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4905.json
index 06c2758eb30..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4905.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4905.json
@@ -1 +1 @@
-{"COMIRNATY": 2.3585392090681263, "GARDASIL": 1.7299658277684475, "HIZENTRA": 1.8319822035714823, "HUMIRA": 1.767433290749532, "MENVEO": 25.032541326903686, "MMRVAXPRO": 2.94402812755673, "NIMENRIX": 6.358764998789755, "PLEGRIDY": 1.9623753087769444, "PREVENAR": 4.1383523031394045, "ROACTEMRA": 1.3666859000898888, "SHINGRIX": 18.19812847694293, "SPIKEVAX": 3.344580535381688, "TOZINAMERAN": 1.214303803778971, "TWINRIX": 6.713910802309224, "VAXZEVRIA": 5.362385642871577, "XOLAIR": 1.1932252081728738}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4906.json
index 56bf381a4fb..8afe0f74b25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4906.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4906.json
@@ -1 +1 @@
-{"ADCIRCA": 3.919718180451196, "ANAKINRA": 4.99459380194368, "APIDRA": 3.8379834481655744, "ARANESP": 1.4380385653453895, "ARAVA": 2.3168242017485885, "BENLYSTA": 4.7028537016138685, "BYDUREON": 7.819829272515478, "BYETTA": 1.221525201840749, "CELLCEPT": 1.621902652830857, "CIMZIA": 1.6775740093521023, "COSENTYX": 1.6051526042248612, "CYMBALTA": 1.6841940555025154, "DARATUMUMAB": 28.256979611010827, "ELIQUIS": 1.3691830802956455, "ENBREL": 3.8850356594788753, "ENTYVIO": 1.3920483166077733, "EXFORGE": 2.5455275806635056, "FORSTEO": 1.5349557427012603, "FORXIGA": 2.008748838720217, "HIZENTRA": 1.4060233749674227, "HUMALOG": 7.845262910914044, "HUMIRA": 2.0152842500579995, "IBRANCE": 3.3460553154616264, "ILARIS": 94.1912156113165, "INLYTA": 2.178475339739858, "INSULIN": 2.939278886159805, "INVOKANA": 4.982933844170973, "JANUMET": 1.2409872752490236, "JARDIANCE": 3.171400740687021, "LANTUS": 5.6097284855433935, "LEVEMIR": 7.943715523025998, "LYRICA": 1.933707695937848, "MEPOLIZUMAB": 1.522033166741562, "METHOTREXATE": 2.8038428788548546, "MYCOPHENOLATE": 3.712961503535044, "NEXAVAR": 1.0071277809811436, "OFEV": 1.3351082743770315, "OPSUMIT": 2.3605882940444314, "PEGASYS": 1.2132496216650768, "RAPAMUNE": 3.538862940170233, "REVATIO": 2.6587300753078886, "RITUXIMAB": 4.079913037962451, "ROACTEMRA": 4.935662320416527, "SIMPONI": 7.508136202735399, "SOLIRIS": 1.863633737888991, "SPRYCEL": 1.418256295558371, "SUTENT": 1.908454669316234, "TRACLEER": 1.7417997769778777, "TRELEGY": 2.81792730857228, "VELTASSA": 11.274868997110266, "VIAGRA": 1.8141562611248676, "VOTRIENT": 1.0617425755582366, "XELJANZ": 9.295619806565076, "XTANDI": 1.6552563002889251}
\ No newline at end of file
+{"INVOKANA": 273.96623485230424, "null": 1.157801816178564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4907.json
index c4584a43e05..e17df90da73 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4907.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4907.json
@@ -1 +1 @@
-{"COMIRNATY": 2.1538551058949587, "COSENTYX": 1.7534177500514203, "ENTRESTO": 1.2177684595799654, "KYMRIAH": 2.921036106234984, "MENVEO": 5.199834042457992, "MICARDIS": 1.6962833923672174, "MMRVAXPRO": 1.177595707170957, "OPSUMIT": 1.8808314223668323, "OPTIMARK": 1.0368625927455544, "REBIF": 19.055221364108395, "SPIKEVAX": 1.52538384276938, "TRACLEER": 1.3683808606161822, "XOLAIR": 1.599905349949241, "null": 1.1805917678886972}
\ No newline at end of file
+{"COSENTYX": 22.419885222713887, "null": 1.2486327047423242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4908.json
index 0abb8bddf8b..1bd89300b8f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4908.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4908.json
@@ -1 +1 @@
-{"EPIVIR": 129.8796683858363, "null": 1.768628644631982}
\ No newline at end of file
+{"ELIQUIS": 5.44030107692668, "NEXAVAR": 30.554153342376058, "TOZINAMERAN": 1.8722219913415263, "null": 0.427565755283664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4909.json
index d1840533d21..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4909.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4909.json
@@ -1 +1 @@
-{"VAXZEVRIA": 11.810765173396954}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/491.json
index be28d34b20e..55981c7c899 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/491.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/491.json
@@ -1 +1 @@
-{"null": 4.627060647228294}
\ No newline at end of file
+{"IRINOTECAN": 808.736956470952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4910.json
index f4ac87ea550..804a36154e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4910.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4910.json
@@ -1 +1 @@
-{"null": 3.792326896754684}
\ No newline at end of file
+{"null": 0.3425776569616238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4911.json
index 9c5f0bff6f5..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4911.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4911.json
@@ -1 +1 @@
-{"COMIRNATY": 2.526008366242428}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4912.json
index fe283265236..db502fe0f6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4912.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4912.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 3.9993227028455474, "BRINTELLIX": 6.135639487946842, "BUPRENORPHINE": 6.108321229144807, "CHAMPIX": 3.700125593768914, "CYMBALTA": 1.507987396767164, "KEPPRA": 3.341601385458941, "LATUDA": 8.188355011155997, "LYRICA": 2.781017828846475, "OLANZAPINE": 3.6690582505569904, "VFEND": 6.288063181292692, "ZYPREXA": 3.7534733630240473, "null": 3.702026827524416}
\ No newline at end of file
+{"BYETTA": 10.311398945272376, "CYMBALTA": 16.5374669705985, "LATUDA": 30.53803614419454, "null": 1.0612988877134155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4913.json
index 4eb968c6f1b..8807d2f9f42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4913.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4913.json
@@ -1 +1 @@
-{"BUDESONIDE": 1.8089207379945296, "KALETRA": 25.918491042939127, "LEVOFLOXACIN": 9.006782357675878, "MULTAQ": 11.484943071370012, "OLANZAPINE": 8.324889743984125, "TAGRISSO": 15.736520794768186, "ZYPREXA": 2.101405788258744, "null": 3.975022039769379}
\ No newline at end of file
+{"CARMUSTINE": 7.934386489609373, "CELLCEPT": 1.092246889269236, "CHAMPIX": 0.6390776094963172, "CICLOSPORIN": 1.0165153224702657, "COMIRNATY": 0.0176154264863913, "COSENTYX": 0.471457116518873, "ELIQUIS": 1.702629574300028, "FORSTEO": 0.483104957502297, "HUMALOG": 0.381330170871917, "IBRANCE": 0.55925537153756, "JANUMET": 0.8819373159068797, "JANUVIA": 1.0526248520045076, "JARDIANCE": 0.5481003121652638, "KEYTRUDA": 0.2467135678708946, "LANTUS": 0.9820446270309758, "PEGASYS": 0.315694059905818, "PEGINTRON": 0.6695960706646531, "PLAVIX": 0.6338371115958551, "RINVOQ": 1.0657807396742154, "SIMPONI": 1.5670457943543654, "STELARA": 1.714631552721413, "SUTENT": 0.5432314627870647, "TREMFYA": 2.302493632626053, "TRULICITY": 1.3951786282061651, "XELJANZ": 0.7917966902454203, "XOLAIR": 0.4260124203935471, "XTANDI": 0.6962480649042964, "null": 8.341315442060948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4914.json
index ed2a8507161..f244519fff4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4914.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4914.json
@@ -1 +1 @@
-{"null": 4.155425732610098}
\ No newline at end of file
+{"null": 2.3276181966549254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4915.json
index 34e7a0795e8..e949df452d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4915.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4915.json
@@ -1 +1 @@
-{"null": 2.5322569562112758}
\ No newline at end of file
+{"COMIRNATY": 0.3067248007897953, "FENTANYL": 38.788493314486736, "LEVEMIR": 13.062758867167908, "SPIKEVAX": 0.2400659051741172, "VAXZEVRIA": 0.2513797985696674, "null": 1.1691404715144078}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4916.json
index fb4b8fff5f9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4916.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4916.json
@@ -1 +1 @@
-{"ADALIMUMAB": 47.79142692684376, "ARAVA": 4.246605494391295}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4917.json
index e109cd2d650..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4917.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4917.json
@@ -1 +1 @@
-{"AIMOVIG": 3.594372556266701, "ATRIPLA": 2.1690106094917314, "BONVIVA": 27.42327193061157, "ELIQUIS": 2.203686274414696, "EVENITY": 17.923837666594252, "FORSTEO": 5.481972941660784, "IBRANCE": 2.644938277439671, "LANTUS": 2.297169921965453, "PEGASYS": 2.891460078326796, "SUTENT": 6.674271686234114, "TRUVADA": 1.7990838436821324}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4918.json
index 0d0272596cf..5121f6f936a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4918.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4918.json
@@ -1 +1 @@
-{"ADENURIC": 180.51049166018075, "GARDASIL": 8.371365617444159, "null": 2.537397259285423}
\ No newline at end of file
+{"RILUTEK": 847.6445785237527, "null": 1.0040424242367023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4919.json
index 39f0ec878bd..4f7cb8d6fae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4919.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4919.json
@@ -1 +1 @@
-{"KYMRIAH": 1719.9631390808895}
\ No newline at end of file
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/492.json
index 11234c864b2..bd735a388d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/492.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/492.json
@@ -1 +1 @@
-{"null": 9.647693326596746}
\ No newline at end of file
+{"PAZOPANIB": 2393.722277868474, "SUTENT": 15.921463651607532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4920.json
index c4502cd0a22..cb6e8d1964d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4920.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4920.json
@@ -1 +1 @@
-{"COVID19": 1.9543097977415045}
\ No newline at end of file
+{"AFINITOR": 1.247729515766535, "ALIMTA": 1.3200400513240922, "APIDRA": 1.3411631799063284, "ARANESP": 1.791573350262495, "AVASTIN": 2.532820138738656, "BONVIVA": 4.123335901182265, "BRILIQUE": 29.38634058723716, "CELLCEPT": 0.9370855478809472, "CHAMPIX": 0.4326899822803758, "CLOPIDOGREL": 14.524151407664773, "COMIRNATY": 0.041115994348084, "CYTARABINE": 1.288902264814017, "DEFITELIO": 17.818560609472588, "EFIENT": 28.402176758269, "ELIQUIS": 11.681012992032276, "ENOXAPARIN": 3.041927510386743, "ENTRESTO": 0.7456399371859855, "ETANERCEPT": 14.148941812547823, "EVEROLIMUS": 5.885428147723778, "EXJADE": 1.6771342191547391, "FORSTEO": 0.8375301960479495, "HEMLIBRA": 13.331516630039411, "I": 389.9155962150428, "IBRANCE": 0.5908320483508187, "IBUPROFEN": 1.650212117384635, "ISCOVER": 21.5939574161558, "JAKAVI": 1.4133769488587236, "JANUMET": 1.5680781566530666, "JARDIANCE": 0.6769454331688716, "KEPPRA": 0.6226297453349818, "KEYTRUDA": 0.6433540839885111, "LANTUS": 0.674948435802961, "LENVIMA": 2.6897151412464675, "LIXIANA": 15.098828263106984, "MIMPARA": 5.117987947110145, "NEXAVAR": 5.518878763099375, "OFEV": 2.6180614604235624, "OPSUMIT": 1.7576509388676609, "PANTOPRAZOLE": 2.037425128309988, "PEGASYS": 0.5453521390032313, "PLAVIX": 22.326501796585944, "SPRYCEL": 1.6523479276103912, "SUTENT": 5.342882235823343, "TICAGRELOR": 9.73669946209261, "TOZINAMERAN": 0.1225435954133864, "TRACLEER": 0.96144040904065, "VAXZEVRIA": 0.0508166141859411, "VOTRIENT": 2.406679903127493, "XARELTO": 3.496552743041361, "XELJANZ": 0.6887354592157475, "null": 1.1871763736338932}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4921.json
index 361c0d4dee4..46e074f71cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4921.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4921.json
@@ -1 +1 @@
-{"ABILIFY": 1.1488849558783418, "ACTOS": 1.541076876940835, "ACTRAPHANE": 6.761780926959728, "ACTRAPID": 2.96696138570018, "AERIUS": 1.9105663470429404, "ALL": 1.858321798432272, "ANAKINRA": 4.989524303724422, "APIDRA": 3.9167986581702574, "AZILECT": 1.934709431994704, "BAQSIMI": 5.664399825894125, "BEDAQUILINE": 1.3169828585043633, "BENZODIAZEPINE": 1.4221374892109686, "BENZODIAZEPINES": 2.279977767315066, "BEXSERO": 3.202554283668737, "BUMETANIDE": 1.261808960321682, "BUPIVACAINE": 2.303789709968207, "BUPRENORPHINE": 1.102171953635022, "CANNABIDIOL": 1.293317034966191, "CARBIDOPA": 1.0098505345105604, "CELSENTRI": 1.6282534528714965, "CHAMPIX": 2.0993366797746926, "COAPROVEL": 1.1708931979043324, "COMTAN": 1.1739248698982092, "CYMBALTA": 1.6875186722165576, "DEXMEDETOMIDINE": 1.3768586992207388, "DRONEDARONE": 4.053540175145463, "DULAGLUTIDE": 1.6517268651129575, "EBIXA": 2.58957657434998, "EMEND": 1.4842621682946433, "ENTACAPONE": 1.0603584409597542, "ENTRESTO": 1.7205818173505711, "EVENITY": 1.5444634161262545, "EVISTA": 1.2554693850898355, "EXELON": 3.422250403130506, "EXFORGE": 1.2084854267005438, "FAMPRIDINE": 2.000328761207167, "FENTANYL": 2.154797297701909, "FESOTERODINE": 25.641298123479583, "FORSTEO": 1.1634305585674294, "GALAFOLD": 1.5273098291210754, "GARDASIL": 4.469268674356597, "GILENYA": 1.1702857750537463, "GLIBENCLAMIDE": 2.5160774022959425, "GLUCAGON": 4.92958606716744, "HUMALOG": 3.46907131798296, "IBUPROFEN": 1.0000752706448008, "INFANRIX": 1.2606429657839948, "INSULATARD": 2.0698264582768218, "INSULIN": 2.562426716071182, "INSUMAN": 2.26309896866658, "IVABRADINE": 1.1023731694934158, "KEPPRA": 1.3055922913780844, "KETEK": 1.9309690863078983, "KETOCONAZOLE": 1.4347703365313107, "LANTUS": 2.91776864610035, "LATUDA": 1.2259839718510983, "LEVEMIR": 1.8393883897546663, "LOXAPINE": 1.9753890834585444, "LUPKYNIS": 1.451966358330282, "LYRICA": 2.09433026303426, "MELATONIN": 1.354831535078902, "MEMANTINE": 1.970033598526234, "MENVEO": 3.8460747118948846, "MICARDIS": 2.2733326443293045, "MICARDISPLUS": 1.1758673291657098, "MIDAZOLAM": 1.5110330819638884, "MIRCERA": 2.6975211508941954, "MIXTARD": 1.3914044377445491, "MMRVAXPRO": 1.583055735432449, "NALOXONE": 4.518094004215677, "NEULASTA": 1.25528862917047, "NIMENRIX": 1.7566640269100295, "NOVONORM": 1.7279719797841104, "OCRELIZUMAB": 1.6408983044336485, "OLANZAPINE": 1.0401052233387305, "OPIOIDS": 2.408752465899624, "PEGASYS": 1.2691061608992718, "PEGINTRON": 1.842575183566976, "PERJETA": 1.4157868438586645, "PREGABALIN": 1.6527286304026934, "PRIALT": 6.701840247718767, "PROPRANOLOL": 1.827792935487944, "RANEXA": 1.346398062411884, "RANOLAZINE": 3.002422979862492, "RAPISCAN": 2.5571452123022893, "REBIF": 3.719894503194017, "REGADENOSON": 12.84259758677844, "REPAGLINIDE": 2.572741501472916, "RISPERIDONE": 1.4546406111557844, "SEMAGLUTIDE": 13.864678498138977, "SHINGRIX": 1.1497114942110491, "SILDENAFIL": 1.6055526464903904, "SILGARD": 3.173172786041904, "SILODOSIN": 8.387300798338616, "SITAGLIPTIN": 2.3883140827112337, "SOVALDI": 2.441487455317065, "SUBOXONE": 2.6181734510103905, "SUBSTANCE": 4.45683785537527, "SYCREST": 1.1498123282789006, "TAMIFLU": 3.35523421962547, "TERIPARATIDE": 1.103439698314041, "TORISEL": 1.2727417522441604, "TOUJEO": 2.022951403150728, "TOZINAMERAN": 1.517087129618688, "TRELEGY": 1.0570961801643315, "TRULICITY": 1.1629200199970695, "TRUMENBA": 26.50042158332387, "TWINRIX": 1.886002435487389, "UNKNOWN": 2.245824837892662, "UNSPECIFIED": 1.0771322870282394, "UROREC": 1.5104047383108157, "VIAGRA": 1.5361247415381851, "VICTOZA": 1.312906777650529, "VIMPAT": 1.6899263977381682, "XOLAIR": 1.0204160763747394, "XTANDI": 1.2457736183437456, "XYREM": 1.3813156226246728, "ZARZIO": 1.762576895125173, "ZYPADHERA": 2.677706478363381, "ZYPREXA": 1.859508434158088, "null": 1.6916918382567514}
\ No newline at end of file
+{"null": 1.040710572737965}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4922.json
index 6bac70326b8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4922.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4922.json
@@ -1 +1 @@
-{"CHAMPIX": 2.421090709512496, "COVID19": 1.2958516544609515, "DULOXETINE": 46.913153769197685, "FAMPYRA": 43.23925065677231, "GARDASIL": 2.9039571759100617, "LYRICA": 6.752290098792746, "OPTIMARK": 5.04898358831433, "PLEGRIDY": 17.12226485150154, "TOZINAMERAN": 1.7114755652561917}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4923.json
index 8aa7b31dc6c..ec31764245c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4923.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4923.json
@@ -1 +1 @@
-{"null": 1.8513909425073325}
\ No newline at end of file
+{"CIMZIA": 3.128070403872572, "HIZENTRA": 13.849102544766325, "IBRANCE": 3.960671050321068, "SIMPONI": 4.354706927023201, "SUTENT": 1.5739633052242183, "XELJANZ": 8.39051971112481, "null": 1.0728669484043518}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4924.json
index e3ac247c317..bff4479e00a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4924.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4924.json
@@ -1 +1 @@
-{"ABATACEPT": 1.7527091133304675, "ABILIFY": 4.889162168256731, "ARAVA": 6.622548449023761, "BUPRENORPHINE": 4.588916946451849, "CHAMPIX": 2.603477485978756, "FENTANYL": 5.287964521708748, "PLAVIX": 9.382258376442618, "SUBOXONE": 3.0588946057884714, "null": 4.636509986348207}
\ No newline at end of file
+{"null": 4.684808851717915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4925.json
index 60ced48d1b6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4925.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4925.json
@@ -1 +1 @@
-{"ABILIFY": 4.214250623596751, "BIKTARVY": 6.791091788636486, "BRINTELLIX": 10.329641100706752, "CHAMPIX": 2.4345156562230468, "CYMBALTA": 1.575828545694914, "DULOXETINE": 4.700682719295856, "FASLODEX": 1.3829867153491562, "INFLIXIMAB": 9.51673247549562, "KEPPRA": 1.3032484623053406, "LEVETIRACETAM": 1.4630870684121875, "SUBOXONE": 1.4389090961467077, "ZYPREXA": 1.1914762768480307, "null": 5.44038396549083}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4926.json
index bd1a7c9cc30..a5ba01d036b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4926.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4926.json
@@ -1 +1 @@
-{"ABATACEPT": 1.727001309719118, "ACLIDINIUM": 9.263379861637183, "ADALIMUMAB": 2.2106161508344417, "ALENDRONATE": 19.47849011603824, "AMGEVITA": 17.46137590846161, "ANAKINRA": 1.960894384762728, "ANORO": 17.521459101361557, "APIXABAN": 17.268819031060907, "APREMILAST": 2.978394408819015, "ARAVA": 3.597968762727217, "ARIPIPRAZOLE": 1.552882175147961, "ATAZANAVIR": 6.757673573466355, "ATRIPLA": 2.3981231852904603, "AUBAGIO": 2.9568122256442715, "AVAMYS": 11.658809588355831, "AZATHIOPRINE": 1.4107306493723275, "AZOPT": 16.78487835844961, "BELIMUMAB": 9.13361982811423, "BENRALIZUMAB": 25.875353987394348, "BUDESONIDE": 9.87751215182506, "CANAGLIFLOZIN": 9.182070803183922, "CAPSAICIN": 9.354370405041324, "CARBIDOPA": 5.758863028851672, "CAYSTON": 76.23873646718333, "CELECOXIB": 1.5761170578142951, "CERTOLIZUMAB": 6.8156675913041225, "CHAMPIX": 1.2222367163426913, "CIMZIA": 3.032854617310936, "DACLIZUMAB": 31.3291419328828, "DAXAS": 16.424389136078307, "DESLORATADINE": 6.004930061983674, "DUPIXENT": 5.512050455085209, "ENBREL": 4.707693381479931, "ENTACAPONE": 2.369763036930724, "ESOMEPRAZOLE": 1.347738436826057, "FAMPRIDINE": 3.0102149107026435, "FIRDAPSE": 1.227648953733786, "FLUTICASONE": 7.182622362253732, "GARDASIL": 1.3984336577360024, "GLYCOPYRRONIUM": 28.87663885538977, "HUMIRA": 3.773238221986897, "HYDROCORTISONE": 1.4181031035793097, "IBRANCE": 1.026973054892799, "IBUPROFEN": 1.016816501935926, "INCRUSE": 6.226696659294275, "INSULIN": 1.4030686042856826, "INVEGA": 1.6795760572979783, "IRON": 1.9940723279377215, "LEFLUNOMIDE": 1.4696208121296883, "LENVIMA": 1.288773705090385, "LIRAGLUTIDE": 37.39284053455656, "LYRICA": 1.7762489314901972, "MEPOLIZUMAB": 25.248698951458405, "METHOTREXATE": 2.61209946774204, "NUCALA": 21.02383876665718, "OMALIZUMAB": 2.7422822870531185, "OPTIMARK": 1.002142738301738, "PANTOPRAZOLE": 3.928475453990444, "QUTENZA": 1.36805523839113, "RISPERIDONE": 1.2877963657827267, "SHINGRIX": 2.4680461370999, "SIFROL": 1.5582580385797644, "SOMATROPIN": 1.4855215274431026, "STALEVO": 1.0051311505345903, "STRIBILD": 2.9151883326726065, "SUBOXONE": 1.227765660044972, "TELMISARTAN": 4.800037831736784, "TOZINAMERAN": 1.7374920601418462, "TRELEGY": 1.4495563547600043, "TRUVADA": 2.090275867570981, "UMECLIDINIUM": 21.10253761371964, "VARENICLINE": 8.131251014982976, "VIREAD": 2.139403117010488, "XELJANZ": 3.2566380396750985}
\ No newline at end of file
+{"null": 2.2357192722022696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4927.json
index 727f0bc5c42..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4927.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4927.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.5010924033491966, "CIMZIA": 3.099942773167552, "COSENTYX": 18.901397180474618, "ENTYVIO": 70.2541207970881, "FAMPYRA": 27.01715793645097, "IDACIO": 167.01291200352358, "KEYTRUDA": 2.2156208566144664, "NPLATE": 11.631305082728998, "RINVOQ": 12.81877212950778, "ROACTEMRA": 24.85376139922004, "SIMPONI": 19.745426658500097, "STELARA": 52.34013902510119, "TREMFYA": 53.96576756411759, "XELJANZ": 4.603716714473935}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4928.json
index 1c4eecb4ec5..117b332867c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4928.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4928.json
@@ -1 +1 @@
-{"null": 1.1196148430104418}
\ No newline at end of file
+{"null": 2.1482279923668317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4929.json
index e5b872ed52f..81a7906fbab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4929.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4929.json
@@ -1 +1 @@
-{"ABILIFY": 1.180302657647445, "ALISKIREN": 3.705976736931941, "ARIPIPRAZOLE": 5.164813251049623, "ASPARAGINASE": 4.746422462442229, "ATAZANAVIR": 4.715409218773686, "ATOSIBAN": 51.716120868502806, "AZATHIOPRINE": 5.583130756397774, "BUPIVACAINE": 10.803296984130249, "BUPRENORPHINE": 20.25032575669563, "CELLCEPT": 1.0771289749963404, "CICLOSPORIN": 9.64185386958937, "CIMZIA": 5.001820523592239, "CINACALCET": 32.968006986081015, "CLOPIDOGREL": 1.5229991784435843, "COMBIVIR": 4.569809732683283, "CYTARABINE": 2.1407826356628017, "DARBEPOETIN": 17.210922654826184, "DARUNAVIR": 12.501062023369682, "DEXAMETHASONE": 7.413601751008866, "EFAVIRENZ": 6.921882996301598, "EMTRICITABINE": 8.66007261104367, "ENOXAPARIN": 17.47392962779129, "EPIVIR": 7.499620128094573, "EPOETIN": 13.5985602262372, "FENTANYL": 11.956497498762486, "HUMALOG": 1.5905293245657928, "HUMAN": 5.652287105920948, "ILOPROST": 135.5415074795063, "INSULIN": 1.7322617113797183, "IRON": 10.99021050548419, "ISENTRESS": 15.759877556169904, "KALETRA": 1.2001914432937706, "KEPPRA": 7.953660196519968, "LACOSAMIDE": 4.229220586169486, "LAMIVUDINE": 6.447978394621438, "LEVEMIR": 3.629158159883025, "LEVETIRACETAM": 5.970938335265829, "MANNITOL": 14.254371169103957, "MICARDIS": 1.6370397393985303, "MIDAZOLAM": 1.9237908210057, "MYCOPHENOLATE": 2.8153908894174893, "NORVIR": 3.490716487831572, "NOVORAPID": 1.2652607172233754, "OSELTAMIVIR": 19.508678938503497, "PANTOPRAZOLE": 2.836875361485474, "RITUXIMAB": 2.10237602363072, "SILDENAFIL": 2.805055652249801, "SOLIRIS": 2.0953899761895527, "SUBOXONE": 20.40497803523439, "TRACTOCILE": 155.90377936877294, "null": 1.7244793092399475}
\ No newline at end of file
+{"CHAMPIX": 7.06368826931453, "CICLOSPORIN": 4.389939675238484, "CLOPIDOGREL": 29.42958477837592, "PLAVIX": 5.214514073925921, "TICAGRELOR": 67.19114694267986, "null": 0.97198472237328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/493.json
index 2af93ecf5b8..ba4f2bf5bb0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/493.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/493.json
@@ -1 +1 @@
-{"null": 2.738922347820625}
\ No newline at end of file
+{"AFINITOR": 3.190398293148186, "ARAVA": 0.5436289730718724, "COMIRNATY": 0.156513187649433, "DOXORUBICIN": 87.17841772880637, "PEGINTRON": 4.49384184019817, "ROACTEMRA": 6.006661137234706, "null": 1.700414187469347}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4930.json
index a6bb639a94d..5c254547900 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4930.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4930.json
@@ -1 +1 @@
-{"APIXABAN": 27.79362773157298, "JARDIANCE": 11.16674980490368, "null": 1.6874884624940454}
\ No newline at end of file
+{"null": 1.1311436028399546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4931.json
index 8535a3e0041..2f4029f3f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4931.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4931.json
@@ -1 +1 @@
-{"null": 3.778876509953263}
\ No newline at end of file
+{"CLOPIDOGREL": 92.80576009556243}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4932.json
index cc66ccf0bd7..abad891fa21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4932.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4932.json
@@ -1 +1 @@
-{"ABACAVIR": 6.529795958369237, "AFINITOR": 1.805905594361783, "ARIPIPRAZOLE": 3.670973717715072, "BIKTARVY": 6.782848910948265, "CLOPIDOGREL": 1.912336471927361, "CYMBALTA": 1.4105637486245586, "DESCOVY": 27.64040309252692, "ENBREL": 1.4397973932773194, "ENTRESTO": 1.5869769688577298, "JARDIANCE": 2.551729823695472, "LANTUS": 1.1014143233775715, "METHOTREXATE": 2.966595679882067, "RINVOQ": 33.65583573680853, "ROACTEMRA": 11.425854238321786, "VIAGRA": 2.413573988820143, "XELJANZ": 2.610811890157499, "ZOSTAVAX": 1.112073791139654, "ZYPREXA": 5.355905437674048, "null": 1.2940301914120216}
\ No newline at end of file
+{"null": 0.9273165750343132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4933.json
index c1e23803af6..a2d9fcc93d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4933.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4933.json
@@ -1 +1 @@
-{"COMBIVIR": 55.48362368470901, "KEPPRA": 18.53886621780069, "LAMIVUDINE": 70.34112268644077, "null": 3.094654202318216}
\ No newline at end of file
+{"COMIRNATY": 0.5511833751979826, "PEGASYS": 2.872197029649099, "null": 1.49547724446007}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4934.json
index 3fef4ec3398..f978edef1b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4934.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4934.json
@@ -1 +1 @@
-{"BONVIVA": 901.5967187241832}
\ No newline at end of file
+{"AVASTIN": 30.11394410185521, "I": 2341.8356390871418, "KEYTRUDA": 3.3626584490213767, "ROACTEMRA": 6.682678226162834, "SUTENT": 1.7319717053820916, "null": 1.3550674907494031}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4935.json
index 832c5f36a4a..9f822add57e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4935.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4935.json
@@ -1 +1 @@
-{"APIXABAN": 2.7156074591696804, "BEVACIZUMAB": 2.848027467709434, "BRILIQUE": 9.76505367420426, "CLOPIDOGREL": 37.284092462076295, "COSENTYX": 5.791728642525092, "DEFITELIO": 31.192443568856344, "ELIQUIS": 16.645373803810696, "ENOXAPARIN": 14.002127200170184, "IBUPROFEN": 2.560607459385219, "LIXIANA": 17.50273654570032, "NEXAVAR": 4.407844073319892, "OFEV": 2.404607702312918, "PLAVIX": 33.28197483813736, "PRADAXA": 24.7932824941684, "REVATIO": 4.3606054968789225, "SPRYCEL": 3.111106895934293, "STIVARGA": 2.869987148046988, "TICAGRELOR": 62.99539964068568, "XARELTO": 65.06573702400466}
\ No newline at end of file
+{"ARAVA": 0.9010677663938385, "CHLORMETHINE": 497.3030796388903, "CLOPIDOGREL": 3.4809516278014287, "DENOSUMAB": 48.31706299587351, "ELIQUIS": 1.42720028645287, "SPIRONOLACTONE": 23.02311044271998, "SUTENT": 0.9528611709465812, "null": 2.83099746324385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4936.json
index 0bfb348da5f..07648dacfbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4936.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4936.json
@@ -1 +1 @@
-{"ABATACEPT": 1.372057266294349, "ADALIMUMAB": 2.3123839575932377, "AERIUS": 9.6073443976647, "AMINOSALICYLIC": 3.048400734091228, "APREMILAST": 16.03664259157772, "ARAVA": 2.5712653021751777, "ATRIPLA": 8.79094575229899, "AUBAGIO": 1.8724969646642604, "BONVIVA": 3.8275476501795023, "BOTULINUM": 4.285149736620262, "COSENTYX": 2.052638464248524, "DOCETAXEL": 2.213641969034443, "ELIQUIS": 2.214796992671167, "EVENITY": 3.490797371104312, "EVISTA": 4.120261704848079, "EXFORGE": 2.221003507566298, "EXJADE": 1.341805896315029, "FAMPYRA": 4.551707006065149, "FORSTEO": 2.7359903862311987, "GALVUS": 3.3910265893179345, "HUMALOG": 4.079368559392479, "HUMIRA": 2.150251795159507, "IBRANCE": 2.649335710807593, "IRON": 8.785541230540646, "KALETRA": 1.0403480763512332, "LANTUS": 3.170695482729567, "LEVEMIR": 3.144520046999083, "LYRICA": 2.794071534996463, "OPSUMIT": 1.1713535926904557, "RAPAMUNE": 3.0883412065560827, "REVATIO": 5.193695716837231, "SIMPONI": 3.4999703139694964, "SOMATROPIN": 9.307119250187409, "SPINRAZA": 6.242113081147199, "STRIBILD": 6.724854728671521, "SUBOXONE": 3.7592135729671607, "TAMIFLU": 2.0152148927423266, "TRACLEER": 1.6244003605649906, "TRELEGY": 3.284768550631055, "TRUVADA": 6.635368640602052, "VELTASSA": 5.364909615279473, "VIAGRA": 5.199416524804963, "VIREAD": 3.7160225128186983, "XELJANZ": 5.522633434697309, "XTANDI": 1.653507597905151}
\ No newline at end of file
+{"SPINRAZA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4937.json
index a390f2a75bd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4937.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4937.json
@@ -1 +1 @@
-{"ARAVA": 1.3526869426679713, "COSENTYX": 14.648129714292685, "JANUVIA": 13.978001519025815, "MEPOLIZUMAB": 12.116768442813347, "METHOTREXATE": 18.264593881615117}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4938.json
index 50ffd88bce0..f07a0f21c9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4938.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4938.json
@@ -1 +1 @@
-{"ABATACEPT": 17.774333238911268, "ACETAMINOPHEN": 31.46455341163997, "ACLIDINIUM": 5.4037397425142055, "ADALIMUMAB": 2.6706352106786118, "AMINOSALICYLIC": 1.0123912537974975, "ANORO": 2.043642694587992, "APREMILAST": 1.0914761986933188, "APREPITANT": 3.8057202539450303, "ARANESP": 1.4601931385918272, "ARAVA": 8.20569673439919, "ARIPIPRAZOLE": 1.2299609881545182, "AVAMYS": 1.6357503376728575, "BELIMUMAB": 5.316073800425885, "BENLYSTA": 1.5317653126284927, "BORTEZOMIB": 2.107260136192868, "BOTULINUM": 1.4251744665853765, "BUDESONIDE": 4.082520661691011, "CELECOXIB": 1.3674450981670234, "CHLORHEXIDINE": 52.15758702987159, "CIMZIA": 20.26161822074207, "COSENTYX": 3.629777892119733, "DAPTOMYCIN": 17.48120855997858, "DARATUMUMAB": 7.665860095136718, "DEXAMETHASONE": 1.1584007668513456, "ENBREL": 3.8164781746322, "ENTYVIO": 2.8379438517107607, "ENVARSUS": 19.765855286211934, "ERELZI": 7.941873051372406, "ESBRIET": 2.2308969863372776, "ETANERCEPT": 7.993038953770923, "FAMPYRA": 1.2121886567179396, "FASENRA": 3.326421035960379, "FILGRASTIM": 1.068024992664265, "FLUTICASONE": 3.513560235833496, "GLYCOPYRRONIUM": 2.5610268125243865, "HIZENTRA": 2.6201207671526983, "HUMIRA": 1.0140477508815005, "HYQVIA": 3.640139125199566, "INCRUSE": 1.1883505516074733, "INFLECTRA": 7.39735095172084, "INFLIXIMAB": 2.406097792199618, "INSULIN": 3.3552902451283595, "IRON": 2.4377833344801867, "KAFTRIO": 17.36542213956028, "KALYDECO": 15.181994393094431, "LEFLUNOMIDE": 2.124087522405213, "MEPOLIZUMAB": 8.454618242478228, "METHOTREXATE": 2.9778639035922114, "NOT": 1.2235623913488731, "NUCALA": 3.50551682711488, "OBINUTUZUMAB": 3.6044861194639073, "OMALIZUMAB": 6.16530331518118, "ORKAMBI": 2.3053675980509354, "PIRFENIDONE": 7.363690924686139, "PLEGRIDY": 1.0319232099820264, "POMALIDOMIDE": 4.200290165033403, "RANIBIZUMAB": 119.9638786744081, "RELVAR": 2.4164460110353843, "REMICADE": 1.0239245559984225, "REMSIMA": 38.60930812577993, "RITUXIMAB": 1.903667091396254, "ROACTEMRA": 2.680866474465975, "SIMPONI": 31.340362958976165, "SPINRAZA": 1.66235556822652, "STELARA": 3.677432021359204, "SYNAGIS": 6.14019488803452, "TOBI": 10.94610738108935, "TORISEL": 1.3016911605490442, "TRELEGY": 5.433508115296665, "ULTIBRO": 13.073612994098845, "UMECLIDINIUM": 6.289517735241842, "XELJANZ": 7.2083470458330545, "XOLAIR": 2.619215877332144}
\ No newline at end of file
+{"SUTENT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4939.json
index 49703889fa3..89e0c1eb07d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4939.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4939.json
@@ -1 +1 @@
-{"BUSULFAN": 48.61019454980439, "CASPOFUNGIN": 314.3160854528656}
\ No newline at end of file
+{"null": 1.4003020621202162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/494.json
index 6aaca4843a7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/494.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/494.json
@@ -1 +1 @@
-{"ZOSTAVAX": 31.48184819255657}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4940.json
index c3c67134a70..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4940.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4940.json
@@ -1 +1 @@
-{"COSENTYX": 21.99319991174285}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4941.json
index 76b5e992626..ff3f7c08c95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4941.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4941.json
@@ -1 +1 @@
-{"ZOSTAVAX": 16.17324292387107, "null": 1.022803258843102}
\ No newline at end of file
+{"ABACAVIR": 0.8918937631332552, "ABILIFY": 0.8356083176246686, "AFINITOR": 0.6595516182094413, "AIMOVIG": 0.4201574118402398, "ARANESP": 1.0959085044949082, "ARAVA": 0.1710812159046149, "AUBAGIO": 1.4610506946860435, "AVASTIN": 5.442533151186426, "AZATHIOPRINE": 1.0222406924757317, "BONVIVA": 2.8241725972947003, "BOSULIF": 1.834235712464397, "BRAFTOVI": 1.5254695197314625, "BRILIQUE": 4.5858711919559525, "BUDESONIDE": 0.2933817083495016, "BUPRENORPHINE": 1.181171954846515, "BYDUREON": 1.2573930695459343, "BYETTA": 1.9495135528405163, "CABOMETYX": 1.880377571519327, "CAELYX": 3.120830111855331, "CELECOXIB": 2.087855976471394, "CELLCEPT": 2.769423631338793, "CHAMPIX": 1.6203653193451266, "CICLOSPORIN": 1.9163611208093028, "CIMZIA": 0.9864414220605694, "CLOPIDOGREL": 10.6387139112476, "COMIRNATY": 0.0392728496922257, "COSENTYX": 1.4962139147217322, "CYMBALTA": 0.4898808392846352, "DARUNAVIR": 8.842963579811087, "DEXAMETHASONE": 0.5523970375678418, "EFIENT": 8.852091763668387, "ELIQUIS": 3.966077684442996, "ENBREL": 0.4522571719703991, "EVEROLIMUS": 3.603101824266253, "EXJADE": 4.162006828725947, "FORSTEO": 1.7121947459962537, "GARDASIL": 0.1963103232433014, "HUMALOG": 0.3454081540007861, "HUMIRA": 0.6652616506870235, "IBRANCE": 0.9070740499960236, "IBUPROFEN": 3.924211168396506, "INLYTA": 1.7821135627540907, "IRESSA": 2.2380691972563773, "ISENTRESS": 3.521040239531981, "JAKAVI": 2.6700429948396933, "JANUMET": 2.7989938620289663, "JANUVIA": 2.6665616954877653, "JARDIANCE": 0.3042401586035925, "KALETRA": 0.8504418236304072, "KEYTRUDA": 1.3519593801854068, "LANTUS": 0.3900751651112589, "LEVEMIR": 0.9244899265297558, "LEVETIRACETAM": 0.9345590434819744, "LEVOFLOXACIN": 0.4166522196200014, "LYRICA": 0.8338945661720585, "MEKINIST": 1.2186563795953227, "METHOTREXATE": 1.4843178037334834, "MICARDIS": 1.5793903716855922, "NEXAVAR": 3.156276516354088, "OLANZAPINE": 0.4416472487592909, "OPSUMIT": 0.4512736263443874, "ORENCIA": 11.267038271481676, "PEGASYS": 0.7585098975546039, "PEGINTRON": 0.2775455739509363, "PLAVIX": 12.061340095384692, "PRADAXA": 5.925922712000488, "RINVOQ": 1.3551607202590965, "ROACTEMRA": 1.2417728287053629, "SIMPONI": 0.8498717532039732, "SPIKEVAX": 0.0472117744849182, "SPRYCEL": 1.569599248118734, "STELARA": 0.3520619195965644, "STIVARGA": 0.6226697045163051, "STRIBILD": 0.3702251859503487, "SUBOXONE": 0.4140111676808427, "SUTENT": 2.081114555939259, "TACROLIMUS": 3.8335378448649, "TASIGNA": 1.4975807184387615, "TICAGRELOR": 7.536851715733031, "TOZINAMERAN": 0.1109083125964585, "VAXZEVRIA": 0.0518803583724639, "VIAGRA": 0.8604463400698267, "VICTOZA": 1.5558464583528582, "VOTRIENT": 1.920458532996648, "XARELTO": 5.426766014721341, "XELJANZ": 2.1746675150777057, "XTANDI": 0.4750657329692738, "ZOSTAVAX": 0.5150158572448753, "null": 1.7978395797538638}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4942.json
index c551a9edeb9..4672c632926 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4942.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4942.json
@@ -1 +1 @@
-{"COVID19": 2.040083672172359, "GARDASIL": 15.272774129780249, "SPIKEVAX": 1.978003838481772}
\ No newline at end of file
+{"ALIMTA": 1.9042892542077905, "AVASTIN": 3.909296305289317, "BRILIQUE": 10.155574444960424, "CELECOXIB": 4.920746983024274, "CELLCEPT": 2.254738112641704, "CHAMPIX": 0.963205987771812, "CLOPIDOGREL": 14.192171559513657, "COMIRNATY": 0.0257134742901066, "EFIENT": 35.39529556850933, "ELIQUIS": 8.474334056030504, "EXJADE": 1.1456899556069322, "FIRDAPSE": 8.53966430168686, "IBUPROFEN": 3.72347004096194, "ISCOVER": 115.956823658567, "KEYTRUDA": 0.8653024108361816, "LIXIANA": 7.031904197190437, "NEXAVAR": 4.340003391782286, "PLAVIX": 34.877867677455946, "SUTENT": 1.3071817032809157, "TICAGRELOR": 20.12180399203093, "XARELTO": 17.499262302920044, "null": 1.7584194250733385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4943.json
index 8b51c8655d8..55d844dc8cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4943.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4943.json
@@ -1 +1 @@
-{"BOSULIF": 49.67300396486864, "ZOSTAVAX": 59.21880598284709}
\ No newline at end of file
+{"null": 1.4568942704774168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4944.json
index b8ef071dd5b..09438caf1ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4944.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4944.json
@@ -1 +1 @@
-{"ATRIPLA": 3.825423780632272, "BIKTARVY": 48.03791963540094, "BUMETANIDE": 111.1047198134594, "BUPIVACAINE": 44.5916838596932, "COSENTYX": 3.207181305701119, "FORSTEO": 4.577759645746135, "HUMALOG": 1.662688874627763, "JANUMET": 4.260525870162717, "TRUVADA": 2.290670895721512, "XELJANZ": 2.5029672295770595, "ZOSTAVAX": 21.522236952455497}
\ No newline at end of file
+{"PLAVIX": 4.851895480572279, "SUTENT": 2.268194674768029, "null": 1.5275709086297995}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4945.json
index d74770405d6..da1fcded91f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4945.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4945.json
@@ -1 +1 @@
-{"ATRIPLA": 4.74401153220382, "CABOMETYX": 4.972943505432412, "COSENTYX": 4.873164840223964, "EVENITY": 76.62288260096102, "EVISTA": 28.93008537881848, "FORSTEO": 20.522031982771782, "HUMALOG": 1.2098314983193763, "IBRANCE": 1.1178226119552608, "MEPOLIZUMAB": 3.095252352220609, "MIRABEGRON": 66.75008605453684, "SIMPONI": 1.6398065434052191, "SUTENT": 1.169309147635458, "TEDUGLUTIDE": 132.1628924135092, "TRUVADA": 5.651228708380304}
\ No newline at end of file
+{"AVASTIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4946.json
index 72a7b66f139..b8b80e495a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4946.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4946.json
@@ -1 +1 @@
-{"ZOSTAVAX": 23.404036088623457}
\ No newline at end of file
+{"JANUMET": 22.94192843431816, "RIBAVIRIN": 38.79697485049733, "null": 0.4252649442617578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4947.json
index a920902fad0..a47596c5825 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4947.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4947.json
@@ -1 +1 @@
-{"BEDAQUILINE": 17.16613767832352, "CICLOSPORIN": 3.272928013394609, "DEXAMETHASONE": 6.040423370051107, "KEYTRUDA": 4.36313853510541, "NEXAVAR": 3.4396696421049247, "PEGASYS": 2.005352668416377, "ROACTEMRA": 9.55864542874819, "SUTENT": 1.3102695149775887, "VOTRIENT": 4.449351553035297}
\ No newline at end of file
+{"JAKAVI": 26.3197505794818, "NEXAVAR": 41.71983923940159, "null": 0.280963907470946}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4948.json
index 0698d039435..f3d9ac3b98a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4948.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4948.json
@@ -1 +1 @@
-{"ALIMTA": 7.515945786741905, "AUBAGIO": 2.9313062166725308, "BEVACIZUMAB": 6.667700423761304, "CELLCEPT": 3.398607704151845, "CIMZIA": 2.7856866297565377, "DABRAFENIB": 25.76589602633331, "DOCETAXEL": 14.324400832077291, "FORSTEO": 2.414260537036764, "GEFITINIB": 47.32440281927434, "LUMYKRAS": 247.78417504984668, "MEKINIST": 20.598264502973123, "METHOTREXATE": 3.4577832475125985, "OLYSIO": 28.043911661689865, "PEMBROLIZUMAB": 8.450147929399304, "PEMETREXED": 86.98840776426681, "ROACTEMRA": 9.563765550138871, "SIMPONI": 6.318837031042986, "SOTORASIB": 136.47393837646254, "STELARA": 9.394738266102213, "XALKORI": 44.00791185422814, "XOLAIR": 5.475644854129506}
\ No newline at end of file
+{"null": 1.7303640841198316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4949.json
index b230a2431c1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4949.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4949.json
@@ -1 +1 @@
-{"GEFITINIB": 369.3220082985871, "MEKINIST": 47.45248308747861, "PEMETREXED": 142.9284234042745, "XALKORI": 85.52356478007565}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/495.json
index fe6d0d3e6f5..9415d4013af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/495.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/495.json
@@ -1 +1 @@
-{"VAXZEVRIA": 25.21322444761289}
\ No newline at end of file
+{"ARAVA": 0.8414249354402341, "CLOPIDOGREL": 15.176292353004264, "COMIRNATY": 0.2729071170325022, "ELIQUIS": 1.8555096357494, "EYLEA": 24.41496107824563, "TICAGRELOR": 39.52333191306073, "VAXZEVRIA": 0.4688650864969953, "null": 1.0766938423770744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4950.json
index e4daed4383e..a0aefd2dde4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4950.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4950.json
@@ -1 +1 @@
-{"ELIQUIS": 4.466800069677869, "LANTUS": 1.83249637973804, "NEXAVAR": 2.8190849298960323, "NPLATE": 11.467003295264314, "STELARA": 4.489651987862212, "XALKORI": 23.50581052782383}
\ No newline at end of file
+{"AFINITOR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4951.json
index c65c3291182..1ed29e321ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4951.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4951.json
@@ -1 +1 @@
-{"IRESSA": 39.052140692189056, "KEYTRUDA": 6.749403110579432, "null": 1.0661762052268746}
\ No newline at end of file
+{"ABACAVIR": 0.359397974304964, "ABILIFY": 0.4706968222456699, "AFINITOR": 0.9127371307126356, "AIMOVIG": 1.1449147274657256, "AMIKACIN": 1.5612642572403197, "AMINOSALICYLIC": 3.522877254108869, "ARANESP": 0.9060543303318672, "ARAVA": 0.3464683928445717, "ATRIPLA": 0.0597376028117951, "AUBAGIO": 1.1673048629849176, "AVASTIN": 1.0563298474710168, "BEDAQUILINE": 1.9909363475718689, "BENLYSTA": 1.1048537825215543, "BETMIGA": 2.879069385533123, "BIKTARVY": 0.8163716085842905, "BONVIVA": 6.879406770703405, "BOSULIF": 1.3424344222439777, "BRAFTOVI": 1.6580155276226185, "BRILIQUE": 2.0741260471710405, "BRINTELLIX": 0.9008570165607896, "BUDESONIDE": 0.5154773264508449, "BYDUREON": 0.7333310733013617, "BYETTA": 5.467658728013177, "CABOMETYX": 0.8867090904809346, "CAPECITABINE": 0.9010964615681678, "CELECOXIB": 4.653093891295279, "CELLCEPT": 1.6037686160771722, "CHAMPIX": 1.308898189991133, "CICLOSPORIN": 1.1780125957191183, "CIMZIA": 0.5094320537812521, "CLOPIDOGREL": 2.9343797874167845, "COAPROVEL": 1.5415632128231893, "COMIRNATY": 0.3679583222007259, "COSENTYX": 0.7726932641937176, "COTELLIC": 2.358326745641816, "CYMBALTA": 0.7164412462797863, "CYTARABINE": 1.4809759876968098, "DACLATASVIR": 5.466515698962911, "DEXAMETHASONE": 0.4042402647656971, "DOCETAXEL": 0.7734214860586032, "DUKORAL": 29.63207932518932, "EFAVIRENZ": 2.4523945742282023, "ELIQUIS": 1.2334741169376116, "ENBREL": 1.104485617734654, "ENTRESTO": 0.9723431068242104, "ENTYVIO": 0.6610745879141686, "ESBRIET": 0.9775038038646464, "ESOMEPRAZOLE": 1.4268296458308551, "EVISTA": 2.2937205032894554, "EXFORGE": 1.9413306393185945, "EXJADE": 2.345159660122176, "FASLODEX": 1.3454089445205302, "FENTANYL": 0.5083469663755926, "FIRDAPSE": 1.5753731918637273, "FORSTEO": 2.2396138309663254, "FORXIGA": 0.8254856921449881, "GALVUS": 2.2680861508945926, "GARDASIL": 1.6088398433499338, "HERCEPTIN": 1.0518621280534322, "HUMALOG": 0.6104120829313352, "IBRANCE": 0.638934303713051, "IBUPROFEN": 1.898170314561478, "INCIVO": 1.0455687380686156, "INLYTA": 0.9724448631705738, "IPILIMUMAB": 2.79945464102805, "JANUMET": 3.2900926155803654, "JANUVIA": 2.674295690074475, "JARDIANCE": 0.5300989718800637, "KAFTRIO": 1.7857486635181583, "KALETRA": 2.915218589387468, "KEPPRA": 0.4469425687319688, "KEYTRUDA": 1.528539321752785, "KISQALI": 2.2851938233121345, "LANTUS": 0.3019406950216135, "LEVETIRACETAM": 0.6307961724058244, "LEVOFLOXACIN": 1.3034354059509672, "LIXIANA": 1.1963590086015468, "LYNPARZA": 1.1036599851730031, "LYRICA": 1.4856206877165177, "METHOTREXATE": 1.841952250564618, "NEULASTA": 0.8989348960681576, "OLANZAPINE": 0.2302973019022738, "OPDIVO": 2.026011428351472, "OPSUMIT": 0.7862917543245922, "PANTOPRAZOLE": 2.5351648943908094, "PEGASYS": 1.0723907823967844, "PEGINTRON": 1.1759625513571714, "PEMBROLIZUMAB": 2.2074963936590506, "PLAVIX": 3.8967190468221258, "PRADAXA": 2.812516685960521, "REMICADE": 1.5711883473185886, "ROACTEMRA": 1.0514751912459253, "RUBRACA": 1.378876416720249, "RYBELSUS": 3.3980543583701888, "SAXENDA": 8.102702654106327, "SIMPONI": 0.830286845033157, "SOLIRIS": 0.4316121826834537, "SPIKEVAX": 0.2670434205164735, "SPRYCEL": 1.6620353866106128, "STELARA": 0.3872773944938798, "SUFENTANIL": 3.1270129199642613, "SUTENT": 2.1008947899329, "TAMIFLU": 0.8439304587585051, "TASIGNA": 0.9552287970736828, "TOZINAMERAN": 0.4131792684582784, "TRACLEER": 0.6641339166018293, "TRULICITY": 1.8787365839610493, "UNSPECIFIED": 5.724904094990235, "VAXZEVRIA": 0.2800552411041749, "VIAGRA": 0.6296685827747184, "VICTOZA": 3.0651218956111297, "VIMPAT": 1.3476512249423152, "VOTRIENT": 0.9158365152648592, "XARELTO": 1.851556394746916, "XELJANZ": 1.0812271282725563, "XOLAIR": 0.741240826682255, "XTANDI": 0.6588287357289615, "XYREM": 2.142776586231483, "ZOSTAVAX": 1.0656248355401272, "ZYPREXA": 1.076016667778483, "null": 1.4294123411835855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4952.json
index 0e200a91226..459cff37cb6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4952.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4952.json
@@ -1 +1 @@
-{"null": 3.438562821726312}
\ No newline at end of file
+{"null": 0.90994491113401}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4953.json
index 29eb886c40b..55c5448c60b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4953.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4953.json
@@ -1 +1 @@
-{"null": 2.045240671351275}
\ No newline at end of file
+{"ARANESP": 1.5826083137081135, "BRILIQUE": 7.42770038110147, "BYETTA": 1.8404304402121088, "CEFUROXIME": 146.00098610311133, "CLOPIDOGREL": 17.82632347946747, "COMIRNATY": 0.0434966041250285, "COSENTYX": 1.2871414220639037, "ELIQUIS": 2.7082534648982475, "HARVONI": 4.270744463220554, "I": 777.4529183729293, "IBUPROFEN": 2.533927960427998, "PEGASYS": 0.9017188098482122, "PLAVIX": 12.551146650699216, "SUTENT": 0.470286310084677, "TICAGRELOR": 18.44878041359304, "null": 2.373431691585142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4954.json
index 56dbb6c7f52..e7ed992a8c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4954.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4954.json
@@ -1 +1 @@
-{"ELIQUIS": 4.785078586457598, "TRELEGY": 39.87834538346229, "XELJANZ": 3.837127476170201, "null": 1.87768622117061}
\ No newline at end of file
+{"PANTOPRAZOLE": 611.0907924671799, "null": 0.6407477151697535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4955.json
index 26ed5c590f6..7b05761470c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4955.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4955.json
@@ -1 +1 @@
-{"AFINITOR": 4.913301794652878, "APIXABAN": 11.503877413520607, "BIKTARVY": 20.874198792914715, "CICLOSPORIN": 5.607872863658767, "CUBICIN": 25.89168983292649, "CYTARABINE": 8.2002024625787, "DEXAMETHASONE": 3.434866768682372, "ENVARSUS": 334.1482293927682, "KEYTRUDA": 2.347257090521638, "LEVOFLOXACIN": 6.1215352835389965, "METHOTREXATE": 3.2079220134819004, "NUCALA": 3.354337926867295, "OMALIZUMAB": 8.00091386457747, "PANTOPRAZOLE": 8.576661420585728, "PEMBROLIZUMAB": 7.839506423332576}
\ No newline at end of file
+{"CLOPIDOGREL": 6.027709141094727, "ELIQUIS": 4.744117817101043, "ISCOVER": 228.4518689559682, "PEGASYS": 1.1101985318529568, "PLAVIX": 16.087951800199697, "XARELTO": 11.77387208209341, "null": 1.7851640415408936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4956.json
index 16e318185e3..7aa318812a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4956.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4956.json
@@ -1 +1 @@
-{"DULOXETINE": 72.77981611879493}
\ No newline at end of file
+{"null": 0.9505518610027304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4957.json
index 20df6992f5f..817eb6d3b07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4957.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4957.json
@@ -1 +1 @@
-{"ACLIDINIUM": 1409.8429305547263, "MEPOLIZUMAB": 45.47689497459437}
\ No newline at end of file
+{"null": 1.5571158263284657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4958.json
index a0b4d21e56e..c00fda98e4f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4958.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4958.json
@@ -1 +1 @@
-{"BUDESONIDE": 867.5748060901936}
\ No newline at end of file
+{"null": 1.6637691735939928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4959.json
index 93c046a7f72..cfffb2dcefb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4959.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4959.json
@@ -1 +1 @@
-{"ACLIDINIUM": 155.189601036973, "ESBRIET": 48.41025827995069, "JANUMET": 29.43764126396596, "OFEV": 39.5815663846807, "OMALIZUMAB": 61.35249931651309}
\ No newline at end of file
+{"ACLIDINIUM": 31.08316455881353, "AFINITOR": 0.9619201276516928, "ALEMTUZUMAB": 3.030407956677545, "ALIMTA": 1.1335698089637405, "AMINOSALICYLIC": 6.3774856230606485, "ARAVA": 0.3298884561473618, "AUBAGIO": 0.824972077529743, "BEDAQUILINE": 4.7031476010580295, "BENLYSTA": 1.246853643739671, "BUDESONIDE": 0.5008495518934942, "BUSULFAN": 1.2465725511158388, "BYDUREON": 0.7469935957716047, "BYETTA": 3.131032720511448, "CAPECITABINE": 1.5252117949274258, "CELLCEPT": 5.296329550581172, "CHAMPIX": 0.4116296739466993, "CICLOSPORIN": 0.8113044234680886, "CIMZIA": 0.6152545075462332, "CLOPIDOGREL": 0.3451667593605802, "COMIRNATY": 0.3159301606667686, "COSENTYX": 0.8400693558274351, "CRIZOTINIB": 24.71402496274566, "CYMBALTA": 0.6686445227557231, "DELAMANID": 14.736930203599782, "DEXAMETHASONE": 0.4357260497712359, "DOCETAXEL": 1.5202233975251938, "ELIQUIS": 0.3573122632912453, "EMPAGLIFLOZIN": 3.326236460959717, "ENTRESTO": 0.6881484595987698, "ENTYVIO": 0.9028108051897578, "EXJADE": 1.2929654668977408, "FASENRA": 1.517109181512049, "FASLODEX": 1.2394120882870387, "FIRDAPSE": 4.008595158741052, "FLUTICASONE": 10.217947959514346, "FORSTEO": 3.731922840555556, "FORXIGA": 2.676138371534414, "GARDASIL": 2.07822184601995, "HUMALOG": 0.5796171280105626, "IBRANCE": 0.3669768119618196, "INCIVO": 3.7179323155082935, "INFANRIX": 11.904862449586364, "INVOKANA": 5.524572912058302, "IPILIMUMAB": 1.5247506152627472, "JANUMET": 1.314096402621214, "JANUVIA": 1.0297742476469132, "JARDIANCE": 5.288829247667135, "KALETRA": 0.9415254014729916, "KEPPRA": 0.8654734160739885, "KEYTRUDA": 0.7441293786783052, "LANTUS": 0.9285485260731904, "LEVEMIR": 1.268688552296512, "LEVOFLOXACIN": 0.8010273847809118, "METHOTREXATE": 2.210900787849329, "MICARDIS": 1.5916920814527382, "MMRVAXPRO": 2.365124807172967, "NEXAVAR": 0.3310287687838137, "NOVORAPID": 0.8868421189719183, "OFEV": 1.0545293225232886, "OMALIZUMAB": 1.0968916747801685, "OPSUMIT": 1.1901953709123498, "PEGASYS": 0.4778873572375701, "PEGINTRON": 1.5378425960037805, "PLAVIX": 0.4536840106745919, "PREVENAR": 5.914651032696907, "PROTOPIC": 38.15957859877299, "RITUXIMAB": 0.8688844679276543, "ROACTEMRA": 1.7007540294273589, "ROTASHIELD": 134.8481763047518, "ROTATEQ": 44.20771096311233, "SAXENDA": 4.977572882944337, "SIMPONI": 1.045398759401941, "SOLIRIS": 2.523809025454057, "SPIKEVAX": 0.1560709267363861, "SPINRAZA": 3.977676834297863, "STELARA": 1.215482152510548, "SUBOXONE": 0.5190247830843138, "SUTENT": 0.7717103395391236, "SYNAGIS": 10.611421096914691, "SYNFLORIX": 49.50427881908052, "TOZINAMERAN": 0.199262837662117, "TRACLEER": 1.3752844470919323, "TREMFYA": 2.773484033560378, "TRULICITY": 1.9302855123711269, "TWINRIX": 2.66917965920307, "VAXZEVRIA": 0.2081507377135776, "VICTOZA": 3.223353219444585, "XELJANZ": 1.5674064353782902, "XOLAIR": 1.2304491132859348, "ZOSTAVAX": 0.4389140332541068, "ZYPREXA": 1.0721011284231583, "null": 1.163394493998316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/496.json
index 7c2ce652b33..d127eee6e98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/496.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/496.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9032819598275217, "VAXZEVRIA": 2.871654462789048}
\ No newline at end of file
+{"ADALIMUMAB": 11.048033027349184, "COMIRNATY": 1.1630982683286153, "EYLEA": 45.61128102611088, "SPIKEVAX": 0.5163502271416773, "VAXZEVRIA": 0.616407581590491, "null": 0.807011845647609}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4960.json
index ec304aba429..fda3bb1350a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4960.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4960.json
@@ -1 +1 @@
-{"ABATACEPT": 3.866684554856171, "ACLIDINIUM": 7.157501990190728, "ACTOS": 1.9986853797094584, "ADALIMUMAB": 1.0640027689844496, "ADCIRCA": 1.221954270660982, "ADEMPAS": 1.3589690834370551, "AERIUS": 1.1633946021332509, "AFINITOR": 4.942857754399042, "ALIMTA": 4.001933990182212, "AMIKACIN": 1.5003914321856708, "AMINOSALICYLIC": 2.213670110821123, "ANAKINRA": 1.8430444963550752, "ANORO": 28.642836382227028, "ANTIBIOTICS": 5.23722881344897, "APIDRA": 1.0532058878432082, "APIXABAN": 3.864715787336343, "AVAMYS": 1.7895691178801405, "AVANDIA": 1.10783323620077, "AZACITIDINE": 1.2272857813090707, "AZATHIOPRINE": 3.1405136066194923, "BENLYSTA": 2.7979213404805585, "BENRALIZUMAB": 3.6909466127852175, "BLINATUMOMAB": 3.920680176271511, "BOSULIF": 1.0911235387059683, "BOTULINUM": 1.351572346498687, "BUDESONIDE": 5.618856803494375, "BUPIVACAINE": 3.1614601372670603, "BUSILVEX": 5.911660749875731, "BUSULFAN": 2.368149783602854, "CANAGLIFLOZIN": 6.6244199844684335, "CANCIDAS": 1.5052669009477375, "CELLCEPT": 3.921506847872158, "CICLOSPORIN": 1.1699038257382837, "CIMZIA": 1.6900735534477838, "COSENTYX": 1.4845463194002586, "COTELLIC": 1.6502942058477852, "CUBICIN": 4.417513773850411, "CYTARABINE": 1.0484727204406583, "DEXAMETHASONE": 1.147639850861657, "DOXORUBICIN": 1.4575522219790231, "DUAKLIR": 25.7133939444531, "ELIQUIS": 1.3152203250244727, "EMEND": 1.694168074813751, "ENBREL": 1.6612558790921663, "ESBRIET": 4.762604899535714, "ESOMEPRAZOLE": 1.024350200773628, "EVEROLIMUS": 2.732633687773769, "FASENRA": 4.149015452965188, "FASLODEX": 1.787936557378019, "FILGRASTIM": 2.136088260073278, "FLUTICASONE": 1.579853958046888, "FORSTEO": 1.690385773998012, "GLIVEC": 1.2407863057595363, "HERCEPTIN": 1.743040526496706, "HIZENTRA": 1.100538037211819, "IBRANCE": 1.7863776193797312, "ICLUSIG": 1.066173607511597, "IMATINIB": 3.404027941339955, "INCRUSE": 5.439000893572809, "INFLECTRA": 3.76549353786466, "INLYTA": 1.5696988295561316, "INVOKANA": 1.5534149147312526, "IRESSA": 26.01572389184868, "JAKAVI": 1.3153894740131429, "JANUMET": 1.1738253620912196, "KAFTRIO": 3.6287429421404673, "KALYDECO": 2.422095250119124, "KEYTRUDA": 3.4140526984933017, "LANTUS": 1.220585143012329, "LONSURF": 1.170069603732374, "LYNPARZA": 1.0844036921674522, "LYRICA": 1.3730513502343298, "MABTHERA": 3.182178222229484, "MEPOLIZUMAB": 1.8079841516996809, "METHOTREXATE": 1.9610937644291977, "MULTAQ": 2.1862765197534446, "MYCOPHENOLATE": 1.2813524863829453, "NAGLAZYME": 2.11455468526692, "NEXAVAR": 1.1157636486083746, "NOXAFIL": 1.102915906692406, "NUCALA": 3.466649002546725, "OFEV": 4.593783756963166, "OMALIZUMAB": 4.268430244772706, "OPDIVO": 1.8438958441089168, "OPSUMIT": 2.10289114582812, "ORKAMBI": 5.239077716003076, "PANTOPRAZOLE": 2.055998363455411, "PRADAXA": 3.127806483717644, "RAPAMUNE": 4.837676975714129, "REBETOL": 1.4368781110971012, "REVATIO": 6.41020708266104, "RINVOQ": 1.9485380544002904, "ROACTEMRA": 2.068675500840253, "SIMPONI": 1.5004327582295698, "SOLIRIS": 1.1947395006732129, "SPINRAZA": 1.1972765580339542, "SPRYCEL": 2.0766461174880537, "SUTENT": 1.1912639426698652, "SYNAGIS": 3.5149700029506, "TAGRISSO": 8.477348622658056, "TAMIFLU": 1.0328881178909912, "TASIGNA": 1.0003306516744763, "TAXOTERE": 2.001515387755858, "TOBRAMYCIN": 2.7022443059056065, "TORISEL": 2.6034988999078728, "TRACLEER": 2.384226814777129, "TRELEGY": 7.440279740818217, "ULTIBRO": 12.398510233168937, "VELTASSA": 1.207571731866586, "VFEND": 2.878510798951254, "VOTRIENT": 1.5532618179698474, "XALKORI": 1.6731233281301467, "XELJANZ": 2.714603459551626, "XOLAIR": 2.1207053982336586, "null": 1.1262856252428872}
\ No newline at end of file
+{"null": 0.5065282367296023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4961.json
index cb836566d0c..8c425c91ace 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4961.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4961.json
@@ -1 +1 @@
-{"NUCALA": 425.78393148472776}
\ No newline at end of file
+{"ALEMTUZUMAB": 186.7711083357592, "CICLOSPORIN": 24.325448498413557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4962.json
index 57a03e64830..7eb9d443b81 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4962.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4962.json
@@ -1 +1 @@
-{"BUMETANIDE": 424.4136683948769, "CLOPIDOGREL": 5.733094397337681, "DUAKLIR": 1217.8860284739233, "HYDROCORTISONE": 34.42613259308436, "MEPOLIZUMAB": 15.38863402841734, "null": 1.358666846538103}
\ No newline at end of file
+{"null": 1.623969081365468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4963.json
index 52044b6b258..2f055504d82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4963.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4963.json
@@ -1 +1 @@
-{"AFINITOR": 8.936308768339808, "ALEMTUZUMAB": 3.77877024318674, "ALIMTA": 2.6404197018067697, "AVAMYS": 1.8634536176973169, "AZACITIDINE": 3.9712134913622257, "AZATHIOPRINE": 3.564204587004535, "BASILIXIMAB": 7.891247692447439, "BEVACIZUMAB": 2.1242273120263704, "CELLCEPT": 1.0827354381823513, "CICLOSPORIN": 6.97723086569875, "CUBICIN": 36.95154364665658, "CYTARABINE": 2.60844876134563, "DEXAMETHASONE": 2.769056280144776, "EFAVIRENZ": 3.808346992907371, "EPIVIR": 5.115284128498868, "EVEROLIMUS": 13.40256776412486, "EXJADE": 4.858509247715617, "FASENRA": 1.917182213086051, "GANCICLOVIR": 4.149060361502943, "HERCEPTIN": 3.122007351119766, "HUMIRA": 1.044470332030712, "IBUPROFEN": 2.066134980560748, "IRESSA": 2.9293397521386213, "JAKAVI": 1.629996950298623, "KEYTRUDA": 1.219979530162134, "LAMIVUDINE": 6.108716639535079, "LEVOFLOXACIN": 1.45271069370295, "MABTHERA": 4.979017783483184, "METHOTREXATE": 1.2547521041683007, "MULTAQ": 5.005714737087952, "MYCOPHENOLATE": 4.099191160928856, "NEULASTA": 5.287983497370491, "NPLATE": 2.1311599455599515, "PEGASYS": 1.1442493664471332, "PEGINTERFERON": 3.349489498541369, "PEGINTRON": 3.834235648844026, "PEMBROLIZUMAB": 1.558689176699563, "PRIVIGEN": 2.6600506191558626, "RAPAMUNE": 11.919951611047733, "ROACTEMRA": 1.053948551801912, "SOLIRIS": 1.2441050934568672, "SPRYCEL": 4.648382745863988, "TAGRISSO": 2.1073581419576777, "TAMIFLU": 1.4895411487662205, "TASIGNA": 1.7289840256174531, "TORISEL": 20.929469791936743, "TRACLEER": 2.5948201457208384, "XOLAIR": 1.9516597146738988, "ZIAGEN": 9.54455091703132, "null": 1.4056094151426943}
\ No newline at end of file
+{"null": 0.7144637947593688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4964.json
index d32d872fe42..0eeae09f8fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4964.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4964.json
@@ -1 +1 @@
-{"INTELENCE": 392.0162968566276, "TRELEGY": 43.811456910452456, "null": 1.7796579602868323}
\ No newline at end of file
+{"EFAVIRENZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4965.json
index b79d330eda9..ae20423517a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4965.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4965.json
@@ -1 +1 @@
-{"ACLIDINIUM": 206.0748539316517, "AFINITOR": 6.287154585902235, "ELIQUIS": 1.7527876783626757, "ESBRIET": 11.491905384648074, "NEXAVAR": 3.069204360384449, "ROACTEMRA": 8.881654310470072, "STELARA": 3.1548024165754045, "VOTRIENT": 9.266638596664054}
\ No newline at end of file
+{"ENTYVIO": 30.824288151535647, "null": 1.2076523677001134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4966.json
index 2dae94eb412..c1bbb4b698c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4966.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4966.json
@@ -1 +1 @@
-{"ACLIDINIUM": 21.55655238078973, "ALIMTA": 1.4668906547525056, "ANORO": 9.887614046288872, "ARANESP": 1.0155656694764177, "AVAMYS": 1.9952514596798845, "BYDUREON": 1.195343697415202, "CELLCEPT": 1.2447815038977417, "CHAMPIX": 1.0577484808014188, "CIMZIA": 1.59879331555279, "DOXORUBICIN": 1.6990881186361764, "ELIQUIS": 2.7448782764379063, "EPADERM": 75.57418514590347, "ESBRIET": 5.6301948807497375, "EVENITY": 2.529412716010654, "FEBUXOSTAT": 3.855896899204271, "FIRDAPSE": 2.565299176101854, "FORSTEO": 2.439717162561026, "HUMALOG": 1.0831899451959914, "INCRUSE": 13.09634456805191, "IRESSA": 3.717607999085944, "JAKAVI": 2.003483681007594, "JANUMET": 1.947984629756089, "JARDIANCE": 1.099258229541305, "LANTUS": 1.9096040935110052, "LEVEMIR": 1.781881937691423, "MEKINIST": 7.526168423111554, "MEPOLIZUMAB": 1.3543582632062383, "MICARDIS": 2.2355367858452704, "NEULASTA": 2.067877888086081, "NPLATE": 3.222570331459524, "OFEV": 5.500278878535834, "OPSUMIT": 1.2833110907593366, "RAPAMUNE": 3.047617199088322, "RELVAR": 2.6712682466585123, "REVATIO": 3.0276096328834146, "REVLIMID": 1.6426178137909928, "RINVOQ": 2.745309089353502, "ROACTEMRA": 2.0629536082075366, "SIMPONI": 2.170709280523144, "SKYRIZI": 3.0857363616944395, "SOTORASIB": 12.518128619614066, "SOVALDI": 2.0633085005915626, "SPRYCEL": 1.1622010545219714, "STELARA": 2.9350670277153568, "TAGRISSO": 8.157281600255411, "TASIGNA": 1.1452052029638546, "TRACLEER": 1.8388239591616429, "TRELEGY": 27.365924611141427, "TREMFYA": 1.5185008899363646, "VELTASSA": 1.3520838440406124, "VFEND": 1.8337834023712984, "VIAGRA": 1.9152148378924725, "VOTRIENT": 1.2550366824903745, "XALKORI": 65.06347904480481, "XELJANZ": 3.0002753876117234, "XOLAIR": 2.021281790340965, "XTANDI": 1.3154407105801351, "null": 2.650877455908001}
\ No newline at end of file
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4967.json
index 14544a23107..a714e50088b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4967.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4967.json
@@ -1 +1 @@
-{"ADENURIC": 13.713146368286308, "AFINITOR": 6.294669682747965, "AVAMYS": 15.652962664824289, "BENRALIZUMAB": 15.764845244284697, "BUDESONIDE": 24.30746981198156, "BUSULFAN": 4.047817045541906, "CABOMETYX": 3.098478607659696, "CYTARABINE": 6.036730017482625, "DEXAMETHASONE": 5.427698759405109, "GANCICLOVIR": 8.68872095946977, "IBRANCE": 1.1732895044612597, "JANUMET": 4.107719595571671, "KEYTRUDA": 7.0467050434274965, "MEKINIST": 2.348278209407672, "MEPOLIZUMAB": 3.523286704059034, "NUCALA": 4.2026060558520255, "OPDIVO": 4.340232951173019, "PANTOPRAZOLE": 8.60266563296315, "RINVOQ": 4.900077487906754, "RITUXIMAB": 2.0082885858915183, "SPIKEVAX": 1.8940661602370652, "TAGRISSO": 22.832835082362784}
\ No newline at end of file
+{"ALEMTUZUMAB": 36.10737791112788, "ASPARAGINASE": 96.65176109842196, "BUSULFAN": 23.699837800169146, "CELLCEPT": 8.80459085195238, "CICLOSPORIN": 7.377721123526189, "CYTARABINE": 13.611437944761864, "null": 0.468804175626112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4968.json
index cf66193e94f..47c7bf06b18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4968.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4968.json
@@ -1 +1 @@
-{"TRELEGY": 22.901769912136853, "VOTRIENT": 10.66369760815222, "null": 2.434975583340463}
\ No newline at end of file
+{"HUMALOG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4969.json
index a6938790a9a..ea24179fd5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4969.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4969.json
@@ -1 +1 @@
-{"BOSENTAN": 75.37673154476656, "KALYDECO": 84.26020092909432, "OFEV": 51.13058623378122, "OPSUMIT": 114.28771266575342, "ORKAMBI": 112.21702162275216, "TRACLEER": 101.10920016670671}
\ No newline at end of file
+{"null": 0.4817574350101159}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/497.json
index ac69f836350..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/497.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/497.json
@@ -1 +1 @@
-{"GARDASIL": 4.818781612933058, "MMRVAXPRO": 20.75810856637325, "VAXZEVRIA": 3.5645009405434225, "null": 1.6504013439007017}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4970.json
index 60eaa6e14e0..331b8fc304c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4970.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4970.json
@@ -1 +1 @@
-{"AMIKACIN": 86.75445446744452, "CELLCEPT": 24.82839929098712, "CICLOSPORIN": 70.52548890089882, "MYCOPHENOLATE": 50.09454433237544, "VFEND": 39.83635048862307}
\ No newline at end of file
+{"PREVENAR": 28.9951664818706, "ROTATEQ": 3799.2644022541904, "SYNAGIS": 11.128835654804124, "null": 0.2917649277175547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4971.json
index f2efe79928f..cab54cd6879 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4971.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4971.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 22.1436252960797, "BENLYSTA": 167.11274984090224, "CELLCEPT": 13.838734601732185, "CICLOSPORIN": 6.179127761541515, "CYMBALTA": 1.9767691212451264, "GARDASIL": 2.612345366539917, "LUPKYNIS": 155.4193937872188, "SIMPONI": 7.734788400795993}
\ No newline at end of file
+{"ARAVA": 2.3185940335131363, "null": 0.6742056969051113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4972.json
index 4d17ebfdf82..3762b95e2f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4972.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4972.json
@@ -1 +1 @@
-{"null": 1.4303389403425195}
\ No newline at end of file
+{"null": 2.059188424572364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4973.json
index 46dca327ccd..db8f8184f54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4973.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4973.json
@@ -1 +1 @@
-{"ABATACEPT": 7.41983028310854, "ADALIMUMAB": 128.471314006873, "AMINOSALICYLIC": 80.78693278955653, "ARAVA": 2.104030994476698, "BOTULINUM": 49.29371591454608, "COSENTYX": 12.144596227927536}
\ No newline at end of file
+{"ABATACEPT": 0.6997926805077471, "ADALIMUMAB": 5.794677887163791, "AFINITOR": 0.9534018393270072, "AMBRISENTAN": 20.69488058713773, "ANAKINRA": 2.880424077499184, "APIDRA": 1.9111877404161504, "AUBAGIO": 1.0309871288347745, "AVAMYS": 5.181633190137428, "AZATHIOPRINE": 3.2419309498510414, "BENLYSTA": 3.293254720976102, "BOSULIF": 6.587175195083663, "BYDUREON": 3.132986776462638, "BYETTA": 1.489347682440225, "CELLCEPT": 1.0536039731253162, "CIMZIA": 2.378401320924316, "COMIRNATY": 0.1312233780714121, "COSENTYX": 0.654630331186414, "CYMBALTA": 0.9345084272349606, "DENOSUMAB": 16.33635949422196, "ELIQUIS": 0.4391333503345531, "ENTYVIO": 2.311352410244072, "EXJADE": 2.065526039016758, "FORSTEO": 0.8499518683612055, "GARDASIL": 0.8339684840896887, "HIZENTRA": 5.269274548160809, "HUMALOG": 2.1760312672208184, "IBRANCE": 1.8086992003338167, "JARDIANCE": 1.4126868046523922, "KEPPRA": 0.6681763813112331, "LANTUS": 0.7011968626820624, "METHOTREXATE": 1.2152049802970155, "OMALIZUMAB": 3.705803929475261, "OPSUMIT": 3.640769655976606, "PEGASYS": 1.5803181149995345, "PEGINTRON": 0.8186435149656555, "REMICADE": 6.332296606166667, "ROTATEQ": 5.232300856243053, "SIMPONI": 1.5498653095725805, "SOLIRIS": 4.56978182774044, "SPIKEVAX": 0.0996309998181756, "SPINRAZA": 8.37322402749472, "STELARA": 1.0656199389255678, "SUTENT": 0.5601787096678728, "SYNAGIS": 3.5622295088234366, "TOZINAMERAN": 0.4508711537986674, "TRACLEER": 4.5318037632284405, "TRULICITY": 3.133622734061845, "VAXZEVRIA": 0.2290718669676949, "VICTOZA": 3.3219372295646106, "XELJANZ": 3.550538916958005, "XOLAIR": 2.138554759247791, "null": 1.1762365589283466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4974.json
index 0d5b932587a..cede950f07a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4974.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4974.json
@@ -1 +1 @@
-{"ABATACEPT": 2.531384307836116, "ADALIMUMAB": 6.555661583689183, "AIMOVIG": 1.655121127156442, "AMINOSALICYLIC": 8.808402035961873, "ARAVA": 2.16926106935813, "CELLCEPT": 1.8079130243840649, "CICLOSPORIN": 1.0402783395361972, "CIMZIA": 9.2787729478573, "COSENTYX": 7.123378979068758, "ENBREL": 3.593545189691137, "ENTYVIO": 11.815927657211178, "HUMAN": 5.220276887316385, "HUMIRA": 18.619915298052817, "LEVOFLOXACIN": 1.2946842474876112, "REMICADE": 29.57930730518999, "SIMPONI": 12.78058568188752, "STELARA": 6.700268150139073, "null": 1.3523986370066785}
\ No newline at end of file
+{"LUTATHERA": 1591.4611163225388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4975.json
index 3a8b3a00ae5..4e7a14b0ef4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4975.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4975.json
@@ -1 +1 @@
-{"CLINDAMYCIN": 251.9226149215846, "COSENTYX": 2.410843394885977, "GARDASIL": 10.666414880869382, "HUMIRA": 4.07583105417339, "SHINGRIX": 3.075687566700229, "SIMPONI": 2.1293046444539776, "STELARA": 3.802317427090035, "TOZINAMERAN": 1.753866659952643, "XELJANZ": 4.507230549518414, "ZOSTAVAX": 2.6831974103452803}
\ No newline at end of file
+{"BYETTA": 97.0623562272919, "JANUVIA": 156.3101028095204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4976.json
index 2d2dd75a737..ee192127fe6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4976.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4976.json
@@ -1 +1 @@
-{"TOZINAMERAN": 5.808362723274055}
\ No newline at end of file
+{"null": 1.2235218531283787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4977.json
index 929cfad0402..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4977.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4977.json
@@ -1 +1 @@
-{"COMIRNATY": 2.034326152502664}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4978.json
index 44f340b1342..ebecbc3bac2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4978.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4978.json
@@ -1 +1 @@
-{"COMIRNATY": 8.075901685742306, "COVID19": 1.2777134506475365, "MMRVAXPRO": 1.1718952986325148, "SPIKEVAX": 3.15479936222887, "TOZINAMERAN": 5.29085486112161}
\ No newline at end of file
+{"IRINOTECAN": 173.54186699462883, "null": 0.3609475605104554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4979.json
index 882003fed7a..85f639e413b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4979.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4979.json
@@ -1 +1 @@
-{"COMIRNATY": 3.726739073197198, "SPIKEVAX": 1.5400268547273368, "TOZINAMERAN": 1.1835314891707611}
\ No newline at end of file
+{"BUMETANIDE": 693.0067012441299, "CLOPIDOGREL": 8.913069979096663, "ELIQUIS": 8.306855830631394, "null": 0.3883522375529764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/498.json
index 492c190aeb5..d5625bf8e91 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/498.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/498.json
@@ -1 +1 @@
-{"ABATACEPT": 6.024795455616933, "ADALIMUMAB": 12.929014598384825, "ANAKINRA": 51.39037263212762, "ARANESP": 12.932783273162114, "NOVOSEVEN": 52.64303882449443, "NPLATE": 20.66925026279972}
\ No newline at end of file
+{"VAXZEVRIA": 0.2683509543678413, "null": 2.44757712703547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4980.json
index bd505fc1970..115c7017e03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4980.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4980.json
@@ -1 +1 @@
-{"CIMZIA": 7.379343097928687, "JAKAVI": 60.97275278868206, "PEGASYS": 2.949003532312677, "PEGINTERFERON": 27.136394997868923, "PEGINTRON": 6.254891066078447, "SIMPONI": 19.511815467239437}
\ No newline at end of file
+{"null": 0.5347424042529709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4981.json
index 60d8d9dd45c..32e254b59e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4981.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4981.json
@@ -1 +1 @@
-{"CELLCEPT": 7.5880545887889586, "CICLOSPORIN": 16.386548271681225, "KEYTRUDA": 10.28222482606338, "null": 1.0590927407288366}
\ No newline at end of file
+{"null": 0.8612234122755659}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4982.json
index a9e7db9ca3e..a182a6a652b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4982.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4982.json
@@ -1 +1 @@
-{"AMIKACIN": 2.9672722226590413, "AZATHIOPRINE": 4.337383149966338, "CICLOSPORIN": 2.145858929418475, "COMBIVIR": 3.043925803844411, "COMIRNATY": 7.142222861389564, "CRIXIVAN": 4.164586373254649, "DOXORUBICIN": 3.1089365297771447, "FILGRASTIM": 6.142341843596005, "GARDASIL": 1.498420059204874, "LAMIVUDINE": 23.85832530233409, "MENVEO": 4.367716418813148, "MMRVAXPRO": 3.674532324759927, "NIMENRIX": 4.069493574997692, "SPIKEVAX": 1.936252066728276, "TOZINAMERAN": 1.0951761894359864, "VAXZEVRIA": 1.0146465626316288}
\ No newline at end of file
+{"ADALIMUMAB": 3.501374511052364, "COMIRNATY": 0.2044629486154457, "GARDASIL": 9.269911676393484, "null": 1.900867124108181}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4983.json
index 0eaef53c1ff..029624c4444 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4983.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4983.json
@@ -1 +1 @@
-{"ACALABRUTINIB": 5.855002439232344, "CABAZITAXEL": 1.6253686918853998, "CARMUSTINE": 1.950538824510266, "COMIRNATY": 7.478022544050123, "COVID19": 1.2304063014340785, "DOLUTEGRAVIR": 1.3229666257412322, "EFAVIRENZ": 1.0705331618320606, "ENFUVIRTIDE": 1.4915405536306456, "FLUCELVAX": 2.2752032308983794, "IBRUTINIB": 1.75006247990514, "IMBRUVICA": 1.2854331434197528, "JCOVDEN": 2.252891895787213, "MENVEO": 1.0515709499399584, "MMRVAXPRO": 2.980412633495709, "NIMENRIX": 1.5930175359639525, "SPIKEVAX": 3.74661948790408, "TOZINAMERAN": 2.488782440488037, "VENCLYXTO": 1.3951030439723564, "VENETOCLAX": 1.0041536582102628, "ZINBRYTA": 1.346193075290922}
\ No newline at end of file
+{"null": 0.968520450522806}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4984.json
index cd63a06170a..a30da275b18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4984.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4984.json
@@ -1 +1 @@
-{"AFINITOR": 6.464462867837981, "CICLOSPORIN": 5.219241904700827, "CLOPIDOGREL": 3.067998196657192, "CYTARABINE": 4.695930233122192, "FASLODEX": 10.972906287254975, "INCIVO": 14.850550416853643, "KEYTRUDA": 3.961273557154689, "MEPOLIZUMAB": 9.329706973203116, "NEXAVAR": 10.950571625321064, "PEGINTERFERON": 5.910927332641744, "STIVARGA": 5.82610558980444, "VOTRIENT": 3.620643576250691}
\ No newline at end of file
+{"COSENTYX": 11.428186571584783, "null": 1.1842073100275303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4985.json
index 0ec19cbcb5f..74fe00cc524 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4985.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4985.json
@@ -1 +1 @@
-{"AFINITOR": 35.32766317841092, "AVASTIN": 16.17035983169931, "BEVACIZUMAB": 15.943838724100871, "CAPECITABINE": 15.400149136561572, "FASLODEX": 19.847313188314537, "IRESSA": 70.33819700889768, "KEYTRUDA": 17.71982293759872, "NEXAVAR": 6.543280564162787, "OPDIVO": 11.343486180993914, "TAGRISSO": 54.89363797859607}
\ No newline at end of file
+{"ARAVA": 0.254895918633001, "COMIRNATY": 0.0345336792145514, "ELIQUIS": 1.7256330401828088, "HUMALOG": 0.7593359745731235, "INSULIN": 3.927741541993596, "LANTUS": 2.40890757089265, "SIMPONI": 2.129365450296284, "STELARA": 2.3742361258586047, "SUTENT": 1.0780187300408377, "VAXZEVRIA": 0.0383456706992069, "XELJANZ": 0.7382636269770388, "null": 5.893459984544338}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4986.json
index 729f811740a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4986.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4986.json
@@ -1 +1 @@
-{"ASPARAGINASE": 10.827097929273894, "COMIRNATY": 1.7829400150285633, "SHINGRIX": 4.846824258841722, "SPIKEVAX": 1.47635914074817}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4987.json
index 5273fd027cf..b5af72cfcf5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4987.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4987.json
@@ -1 +1 @@
-{"PEGINTRON": 15.5253665329719}
\ No newline at end of file
+{"ABACAVIR": 0.2585246053109399, "ABATACEPT": 6.273051201594593, "ABILIFY": 0.3120520189616417, "ACETAMINOPHEN": 14.645169581619932, "ACETYLSALICYLIC": 13.929614256906678, "ADALIMUMAB": 4.450068141186018, "ADCIRCA": 1.4267467733067425, "ADEMPAS": 1.5867541170053232, "AERIUS": 0.9471767383525524, "AFINITOR": 0.3523762183086601, "AIMOVIG": 0.9820290298255854, "ALIMTA": 0.278904398043111, "ALISKIREN": 11.264793254731003, "AMIKACIN": 2.2058439510060857, "AMINOSALICYLIC": 1.3399484329400468, "ANAKINRA": 1.543829173240772, "ANTIBIOTICS": 1.73077295212327, "APIXABAN": 0.1159905797379662, "APREMILAST": 3.0132122026620216, "APREPITANT": 21.183754298772264, "APROVEL": 0.7394636916068354, "ARANESP": 0.2890765632266286, "ARAVA": 4.318883931143318, "ARIPIPRAZOLE": 0.4570936192467167, "ASPARAGINASE": 0.4347680708645515, "ATAZANAVIR": 0.6315659960825872, "ATRIPLA": 0.1502247453042054, "AUBAGIO": 2.746026822295664, "AVANDAMET": 0.3572018802644077, "AVANDIA": 0.2100430683106395, "AVASTIN": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4988.json
index 07638cfed09..2f2f718ab86 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4988.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4988.json
@@ -1 +1 @@
-{"AIMOVIG": 46.122476759013765, "null": 1.0424139146894698}
\ No newline at end of file
+{"APTIVUS": 4701.065232172242, "null": 2.1373771463912843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4989.json
index 5a6f7dc3dc6..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4989.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4989.json
@@ -1 +1 @@
-{"CELLCEPT": 65.92093004617628, "CICLOSPORIN": 23.76558147673437}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/499.json
index 28a15fa12ff..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/499.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/499.json
@@ -1 +1 @@
-{"COMIRNATY": 7.484139599408403}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4990.json
index 286d6f99b3c..62a388c1084 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4990.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4990.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 147.01611245066317, "AUBAGIO": 11.750472849913418, "AZATHIOPRINE": 49.83377020343119, "LEMTRADA": 158.77695140779184}
\ No newline at end of file
+{"BLINCYTO": 549.966731309946, "CLOPIDOGREL": 9.08584256212102, "IBUPROFEN": 16.01021425643838, "null": 1.580136992732906}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4991.json
index ec8ed0f3b7c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4991.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4991.json
@@ -1 +1 @@
-{"AFINITOR": 4.704634047013764, "ALEMTUZUMAB": 27.1582447485189, "ALIMTA": 2.50187372835504, "APIDRA": 1.5728831391968965, "ARIPIPRAZOLE": 17.935804039484506, "AUBAGIO": 9.07767323526001, "AZACITIDINE": 4.51923658288471, "AZATHIOPRINE": 1.994685178725808, "BETAFERON": 6.762588910126118, "BEVACIZUMAB": 5.269658418720744, "BLINCYTO": 48.75910590826577, "CARIPRAZINE": 45.00167105885801, "CICLOSPORIN": 2.5497531584436124, "CLADRIBINE": 27.903304097236344, "CLOPIDOGREL": 1.104363844261249, "COSENTYX": 1.064335983216428, "CYTARABINE": 4.575501663910246, "DARZALEX": 3.8959742743840735, "DEXAMETHASONE": 1.3999468917545372, "DOCETAXEL": 4.095361731196704, "DOXORUBICIN": 7.865678461439518, "ENTRESTO": 2.484464169302409, "EXJADE": 1.9519658258322223, "FAMPYRA": 8.259070522120584, "GAZYVARO": 11.794093682792798, "GILENYA": 42.09043696906324, "IBRANCE": 2.572321939252668, "ICLUSIG": 2.385453769951053, "JAKAVI": 4.880386646944058, "KESIMPTA": 29.657195624357826, "KEYTRUDA": 1.0140587237794834, "KISQALI": 4.53511348170126, "KYMRIAH": 22.333219464869316, "KYPROLIS": 4.577901740844326, "LEFLUNOMIDE": 3.422720480392464, "LEMTRADA": 33.57313614709771, "MAVENCLAD": 326.85481159665795, "MEKINIST": 3.5939439380494864, "METFORMIN": 19.43411798016228, "METHOTREXATE": 3.666409925860428, "OBINUTUZUMAB": 21.73966608870621, "OCRELIZUMAB": 18.01233369918397, "OLANZAPINE": 4.587936696652833, "PEGASYS": 1.26326611729336, "PEGINTERFERON": 1.2617733165222176, "PEGINTRON": 1.643124807179894, "PLEGRIDY": 8.930617986823266, "RINVOQ": 2.376827763762872, "RITUXIMAB": 6.777745947608089, "ROACTEMRA": 1.213833611898929, "SOLIRIS": 1.2652762817676182, "TEMODAL": 23.103146852237835, "TOPOTECAN": 8.37237025275072, "VENETOCLAX": 5.189973608480049, "VFEND": 1.3326696910993947, "XELJANZ": 2.131806248967955}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4992.json
index 8a0af76ff9a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4992.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4992.json
@@ -1 +1 @@
-{"AFINITOR": 2.8116550337994286, "ARAVA": 2.9050355953365687, "ARIPIPRAZOLE": 9.74018195540024, "AUBAGIO": 3.820953428674964, "CICLOSPORIN": 3.888209613798106, "CYTARABINE": 4.368453748466752, "ENBREL": 1.9775908156702693, "GLIVEC": 30.45990786871446, "IBRANCE": 3.785180184443382, "JAKAVI": 5.885034663283319, "PEGASYS": 3.182507242259926, "RINVOQ": 5.071809767424735, "RUXOLITINIB": 24.70879291504317, "VENCLYXTO": 29.55071079807676, "ZYPREXA": 1.8653014181280143}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4993.json
index a944f7267eb..e50c6efbc61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4993.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4993.json
@@ -1 +1 @@
-{"CICLOSPORIN": 8.505879054879587, "LEVOFLOXACIN": 6.7073626316054105, "null": 2.552822903877229}
\ No newline at end of file
+{"null": 0.2255961473406682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4994.json
index b6dae8f4db5..b810b2f977d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4994.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4994.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 48.71873892507818, "ENTRESTO": 6.499894652432314, "LEMTRADA": 99.34423702853086, "OMALIZUMAB": 10.779133786317669, "ZOSTAVAX": 4.5548006185633945}
\ No newline at end of file
+{"CIMZIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4995.json
index e8a410cafa8..15acb6c51c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4995.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4995.json
@@ -1 +1 @@
-{"IBRANCE": 12.376931092724089}
\ No newline at end of file
+{"null": 1.0596355080941091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4996.json
index 15836c7d4d5..aaa582272f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4996.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4996.json
@@ -1 +1 @@
-{"null": 3.0938723142390154}
\ No newline at end of file
+{"ABACAVIR": 0.2179945343413667, "ABILIFY": 0.1163454563742621, "ADCIRCA": 0.7799061595875707, "ADEMPAS": 1.1056657775920218, "ADVATE": 1.5795452091837825, "AFINITOR": 0.8925366999845326, "ALEMTUZUMAB": 0.6167365191776389, "ALIMTA": 0.7751028208094961, "ALISKIREN": 1.562796163091152, "AMBRISENTAN": 1.1163910333927871, "AMIKACIN": 1.9251311132092208, "APIDRA": 0.1970789527095941, "APIXABAN": 1.4802533742360988, "APROVEL": 0.9300608172508594, "ARANESP": 0.5216184471247081, "ARAVA": 0.1144546860691522, "ARIXTRA": 4.525780544756375, "ASPARAGINASE": 0.6908854863211643, "ATRIPLA": 0.0105241064160228, "AUBAGIO": 0.157480787528723, "AVANDIA": 0.2944270611241068, "AVASTIN": 1.326248506567998, "AXITINIB": 0.5777485564203001, "AZACITIDINE": 0.6320502010745939, "BARACLUDE": 0.7784580586921654, "BASILIXIMAB": 0.9226408827056196, "BENLYSTA": 0.1867230853750193, "BEVACIZUMAB": 2.0859819618239595, "BIVALIRUDIN": 11.818976646273246, "BLINCYTO": 2.7820656683259557, "BLINDED": 7.374994973018202, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4997.json
index 4538e54e67c..ec24beb5faf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4997.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4997.json
@@ -1 +1 @@
-{"MICARDIS": 28.22185375056543, "null": 5.669039459795369}
\ No newline at end of file
+{"COMIRNATY": 0.5160977125315291, "null": 1.4855557950686302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4998.json
index 67aa9f77735..c71d357b38a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4998.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4998.json
@@ -1 +1 @@
-{"IPILIMUMAB": 558.4777228864215, "KEYTRUDA": 15.2176430654473, "OPDIVO": 110.31049889217404, "PEMBROLIZUMAB": 41.1719771148286, "YERVOY": 83.95034300033848}
\ No newline at end of file
+{"COMIRNATY": 0.1519644476099975, "LEVETIRACETAM": 14.053173956490076, "OLANZAPINE": 10.898148469486651, "null": 1.806880476825924}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4999.json
index 545cc73a395..3442118ffac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4999.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/4999.json
@@ -1 +1 @@
-{"CICATRIZANTS": 2494.937340658309, "CICLOSPORIN": 11.031136436099022, "null": 1.9149017897626472}
\ No newline at end of file
+{"AIMOVIG": 2.094159217608264, "ARAVA": 0.7519809702229044, "BENLYSTA": 4.824353772710448, "BUSULFAN": 23.394009522213853, "CICLOSPORIN": 2.0516337434518856, "CIMZIA": 2.0417458194208997, "COMIRNATY": 0.0734949517078243, "COSENTYX": 3.096860271644963, "ELIQUIS": 1.039453332940182, "ENTYVIO": 4.299004256089062, "EXJADE": 1.7769657248534847, "FORSTEO": 1.692397955016376, "HUMALOG": 1.264790847535188, "HUMIRA": 4.626812978984777, "IBRANCE": 0.996117284447704, "JANUMET": 1.923143631415796, "JARDIANCE": 2.808910124439997, "LANTUS": 0.7859195721265371, "NAGLAZYME": 22.614233901482383, "PEGASYS": 1.809792729366135, "PEGINTRON": 3.210533593246148, "SIMPONI": 3.4691956295235644, "SOLIRIS": 3.2075994660017324, "SOMATROPIN": 38.17183352978912, "SPIKEVAX": 0.0621189004167899, "SPINRAZA": 18.743216724599115, "SPRYCEL": 3.6992038061813335, "STELARA": 3.042406608623666, "SUBOXONE": 1.9184849920662457, "SUTENT": 1.0035547122403103, "TRACLEER": 2.727520721167108, "VAXZEVRIA": 0.042935650068296, "VOTRIENT": 1.795028406889002, "XELJANZ": 3.5724520560017154, "null": 0.8803975114670834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5.json
index 89d67575595..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5.json
@@ -1 +1 @@
-{"AVASTIN": 9.172792028809967, "BEVACIZUMAB": 6.029422655673468, "BORTEZOMIB": 39.64266638877553, "CIMZIA": 5.403765303250289, "DEXAMETHASONE": 4.130620441731502, "ENTYVIO": 11.885365636094624, "HUMIRA": 4.089612509281598, "JANUMET": 6.532704798762095, "JANUVIA": 5.411829508548316, "KEYTRUDA": 1.2635065494184738, "LANTUS": 1.6038515231013897, "NEXAVAR": 3.4208625086148183, "REMICADE": 19.104396055116244, "ROACTEMRA": 9.802551288980698, "SIMPONI": 2.7112756746622257, "STELARA": 6.960912366184648, "STIVARGA": 4.218059667625735, "SUTENT": 2.33927761709552}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/50.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/50.json
index fd492b8d793..f99490a5690 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/50.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/50.json
@@ -1 +1 @@
-{"AERIUS": 3.154990370031147, "AIMOVIG": 1.7212877628254848, "APIDRA": 1.2787023908881283, "AUBAGIO": 1.8400339400273256, "BARACLUDE": 5.522991508505197, "BENLYSTA": 1.7676422405261552, "BETAFERON": 2.312950445121351, "BIKTARVY": 1.1290536482493143, "BRIVIACT": 1.5723142577875973, "BUPRENORPHINE": 2.8355616895806506, "BUVIDAL": 11.042530920582866, "CELLCEPT": 1.6936570326264857, "CETROTIDE": 41.36617298931657, "CIMZIA": 2.6893184239613017, "CINRYZE": 4.352654143550742, "COMBIVIR": 7.264560865183492, "CYMBALTA": 2.4898774190923567, "DARUNAVIR": 3.973337641069544, "DOLUTEGRAVIR": 3.1330095999477057, "DULOXETINE": 1.0077811194557982, "EFAVIRENZ": 16.75952185738349, "ELLAONE": 11.008724546845963, "EMTRICITABINE": 2.942096135529341, "ENOXAPARIN": 2.136548111081094, "ENTECAVIR": 3.2826850280997317, "ENTYVIO": 3.2589633691132947, "EPCLUSA": 2.4904397223012094, "EPIVIR": 2.824132659772705, "ESMYA": 4.303600445537499, "EVRA": 10.26560903728218, "FASENRA": 1.1112848513675189, "FIASP": 1.546294727852897, "FOLLITROPIN": 44.88515405519594, "GARDASIL": 4.204782983496123, "GENVOYA": 4.043792838386082, "GONALF": 15.605549896270018, "HUMAN": 1.140711964314095, "INSULATARD": 6.60193873952468, "INTELENCE": 4.546432581542087, "ISENTRESS": 12.24250372988332, "KAFTRIO": 5.801758721123785, "KALETRA": 3.588582679833056, "KALYDECO": 2.9975189812819782, "KEPPRA": 4.10725222549644, "KESIMPTA": 2.745017414611656, "KUVAN": 19.63690358637492, "LACOSAMIDE": 2.1361917251404274, "LAMIVUDINE": 2.324682801906542, "LANTUS": 1.4691903077835218, "LATUDA": 1.171057653375401, "LEMTRADA": 1.313873706784329, "LEVEMIR": 6.708010821351965, "LEVETIRACETAM": 4.061530013123205, "MAVENCLAD": 2.4906783256451277, "MIXTARD": 4.915194563394945, "NORVIR": 7.254318368077092, "NOVORAPID": 1.303322830970982, "ORGALUTRAN": 23.42208079717694, "OVITRELLE": 9.620444076127043, "PEGASYS": 2.114093662417026, "PEGINTRON": 2.320057112257917, "PLEGRIDY": 2.48365168228427, "PUREGON": 271.38723846364684, "REBETOL": 1.403725837608477, "REMICADE": 2.665193559768155, "REYATAZ": 5.654078537973878, "ROACTEMRA": 1.3889872538861012, "SAXENDA": 2.41651665995451, "SIMPONI": 1.155584650256459, "SKYRIZI": 2.6603026197685966, "SOLIRIS": 1.411360771963905, "SOVALDI": 1.315793410226482, "STELARA": 4.548898709347866, "SUBOXONE": 13.991029093548203, "TAMIFLU": 1.1735536197312166, "THYROID": 227.04082780582536, "TOZINAMERAN": 1.9147005016504812, "TREMFYA": 2.4410437219236285, "TRIUMEQ": 2.1855466614040524, "VICTOZA": 1.0513409242950544, "VIMPAT": 1.7393219741442492, "VIREAD": 1.907782076994284, "XOLAIR": 4.235924985411844, "null": 1.3075913985769}
\ No newline at end of file
+{"null": 0.98574606972409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/500.json
index 4a400843761..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/500.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/500.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 12.204571865402157, "FENTANYL": 8.217520547646828, "MIDAZOLAM": 19.5927804513776, "OLANZAPINE": 65.76881218578033, "OXYBUTYNIN": 54.25472618169631, "TOVIAZ": 14.658867231176783, "ZYPREXA": 4.0707804444432965, "null": 2.6037678651474696}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5000.json
index baee50e298b..2587392b6a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5000.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5000.json
@@ -1 +1 @@
-{"JAKAVI": 6.907672565156201, "RITUXIMAB": 4.593567857445642, "ROACTEMRA": 4.453725117219718, "SIMPONI": 3.1898214192986534, "SPRYCEL": 10.32387784063538, "STELARA": 2.5500494780499463, "null": 1.5424629425902572}
\ No newline at end of file
+{"ADALIMUMAB": 1.2050063683281356, "BUDESONIDE": 2.2108210901375727, "CIMZIA": 2.249110812914209, "COMIRNATY": 0.4853224405349031, "COSENTYX": 4.1802208525566975, "CYTARABINE": 8.352669647091659, "DEXAMETHASONE": 5.3076534373207815, "ELIQUIS": 0.7615768132109558, "ENBREL": 3.051195567808402, "ENTYVIO": 19.361955417513503, "FORSTEO": 2.985178015294516, "HUMIRA": 7.803359662415743, "IBUPROFEN": 3.823729664809397, "KEYTRUDA": 1.2878558948878172, "ROACTEMRA": 4.278317981356002, "SIMPONI": 2.1758300744304524, "SPIKEVAX": 0.2438378507937142, "STELARA": 2.706037651464128, "SUTENT": 1.0784650669019022, "TOZINAMERAN": 0.2583375805091149, "VAXZEVRIA": 0.1613068507755661, "XELJANZ": 1.2543423737378991, "null": 1.001118262278306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5001.json
index 1ac98797ab1..9de39b445e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5001.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5001.json
@@ -1 +1 @@
-{"ABACAVIR": 2.0673110052091954, "AFINITOR": 3.349879022962376, "ALIMTA": 2.48076188490676, "BYDUREON": 2.0431123165066314, "CELECOXIB": 14.568999832387243, "CIALIS": 8.494286139900328, "CLOPIDOGREL": 14.249488569813913, "COMIRNATY": 1.4780087920078295, "ELIQUIS": 1.1988020517354705, "ESOMEPRAZOLE": 4.770843793537126, "FASLODEX": 9.580888153668855, "FULVESTRANT": 7.559811564097917, "HERCEPTIN": 7.097262975626716, "HUMALOG": 1.146472095192985, "IBRANCE": 8.07985345850302, "IMBRUVICA": 10.47366588239726, "IRBESARTAN": 4.704948622008581, "MEKINIST": 3.579509541583436, "OCEAN": 171.59470648540855, "OPTIMARK": 1.7347687974555337, "RAPAMUNE": 15.377927480648806, "TOZINAMERAN": 1.597828063326282}
\ No newline at end of file
+{"SUTENT": 3.357414708652275, "null": 1.3601150684625565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5002.json
index 528b6f55181..59975fe9979 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5002.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5002.json
@@ -1 +1 @@
-{"null": 1.6098723398614427}
\ No newline at end of file
+{"null": 1.6679598926299606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5003.json
index b0dc27cdf88..b1d4501c13f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5003.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5003.json
@@ -1 +1 @@
-{"ASPARAGINASE": 3440.467664101077}
\ No newline at end of file
+{"null": 0.7375443275018408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5004.json
index 191fd22e08e..5fd70b7ebe1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5004.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5004.json
@@ -1 +1 @@
-{"ASPARAGINASE": 2.085845204885646, "AZATHIOPRINE": 1.84856261001636, "BARACLUDE": 5.541480638555672, "BENLYSTA": 2.2037318005382605, "BIKTARVY": 3.6713867640859537, "BYETTA": 1.271018484382453, "CANCIDAS": 5.136868806508928, "CARMUSTINE": 18.73150043133445, "CELLCEPT": 9.166852715532633, "CICLOSPORIN": 4.771217099927423, "CIMZIA": 1.6149596274413949, "COSENTYX": 1.5434309640403214, "CYTARABINE": 5.557509956389152, "DESCOVY": 9.143998226139692, "DEXAMETHASONE": 1.897843765309448, "DOXORUBICIN": 2.988285940887218, "ELIQUIS": 1.0761190116398904, "ENBREL": 3.4998076706520127, "ENTYVIO": 1.580063074885871, "EPIVIR": 3.4342327172845644, "ESOMEPRAZOLE": 3.873476774973775, "EVENITY": 2.698702429827353, "EVISTA": 2.3271515831106515, "EXJADE": 1.1930169984245906, "FASLODEX": 1.014108116150391, "FORSTEO": 1.124587447221567, "HARVONI": 2.370026319083788, "HERCEPTIN": 2.0960493033904832, "HIZENTRA": 2.256366044162881, "HUMIRA": 2.097079132268074, "ISENTRESS": 5.141574378086152, "JAKAVI": 3.2886400772214004, "JANUMET": 2.301565927996368, "KALETRA": 2.7992081760117733, "KYMRIAH": 7.175316025947196, "LANTUS": 1.2251697436126474, "MABTHERA": 4.692779402081943, "METHOTREXATE": 6.170391237017313, "NEULASTA": 5.950220864120438, "NORVIR": 7.656605140753281, "NPLATE": 11.45106539331197, "OLANZAPINE": 1.7260990634944966, "PEGINTERFERON": 1.3242615268411746, "PEGINTRON": 3.008843057415183, "RAPAMUNE": 7.338574276139948, "REMICADE": 6.843388527387275, "RINVOQ": 5.861253074952829, "RITUXIMAB": 4.67503546461384, "SIMPONI": 4.334434223123927, "SKYRIZI": 9.202427564839976, "SOVALDI": 6.231909913666382, "SPRYCEL": 1.959426712905578, "STELARA": 5.056050739083417, "TIVICAY": 10.450593910608385, "TRELEGY": 1.8277140713015083, "VFEND": 1.7779605399996288, "VIAGRA": 1.1329084893991577, "XELJANZ": 4.034631811242523, "XOLAIR": 3.184390382058309, "YESCARTA": 12.77224862846974, "ZOSTAVAX": 1.6129594080223997}
\ No newline at end of file
+{"APTIVUS": 1714.2496582015333, "null": 2.039943691420396}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5005.json
index 2809945fbea..d8b9347619d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5005.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5005.json
@@ -1 +1 @@
-{"ATEZOLIZUMAB": 1596.3535557185337}
\ No newline at end of file
+{"AIMOVIG": 7.849754223527122, "AUBAGIO": 1.849426111077998, "BEVACIZUMAB": 3.7108926359442544, "BUPRENORPHINE": 3.939111830684285, "CELLCEPT": 2.141105188195248, "CHAMPIX": 1.4023199522991805, "COMIRNATY": 0.323230486601525, "COSENTYX": 1.813962679018124, "ELIQUIS": 0.7883574035994826, "ENTRESTO": 1.9063607270866183, "GARDASIL": 2.099541604819133, "IBRANCE": 1.1379858163996768, "KEYTRUDA": 0.8820754724729282, "LEVOFLOXACIN": 4.398368534663399, "PEGASYS": 0.692725683964273, "SPIKEVAX": 0.1888877382970342, "SUTENT": 1.1471832160401496, "TOZINAMERAN": 0.2176975375791998, "TRACLEER": 2.457210643549166, "VAXZEVRIA": 0.1438553036281798, "ZYPREXA": 1.5766196217330264, "null": 1.6391695534592856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5006.json
index 48099f7bb7a..fbfc01efcec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5006.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5006.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 23.22435633524737, "AMIKACIN": 3.1734161064888395, "ASPARAGINASE": 10.253602836845584, "AUBAGIO": 12.88293630942308, "AVASTIN": 1.4593412768009966, "AZATHIOPRINE": 4.64123551442051, "BASILIXIMAB": 6.699503461802639, "BENLYSTA": 2.593712939407104, "BETAFERON": 3.0272881448863496, "BEVACIZUMAB": 1.757848984363236, "BORTEZOMIB": 6.087349356498266, "BUSULFAN": 2.9730582623370165, "CARFILZOMIB": 6.26311114086344, "CARMUSTINE": 7.681563915256989, "CELLCEPT": 5.901356450246229, "CICLOSPORIN": 2.711468098947762, "CLADRIBINE": 68.82968895258274, "CLOFARABINE": 23.736809040512, "COTELLIC": 3.783710496363629, "CYTARABINE": 2.077239725416044, "DARZALEX": 11.564370618507894, "DEXAMETHASONE": 7.590006305188066, "DOCETAXEL": 2.9178734386698912, "DOXORUBICIN": 4.208275759679525, "EFAVIRENZ": 3.9351336551695297, "FAMPYRA": 8.924382360284124, "FASENRA": 1.1480285304845603, "FUZEON": 42.21135955493028, "GANCICLOVIR": 3.5224167646458038, "GAZYVARO": 10.1813265001177, "HALAVEN": 4.667670654744531, "INCIVO": 2.871220037072409, "IRBESARTAN": 9.354812321814732, "IRINOTECAN": 2.2216070985987826, "JAKAVI": 3.1371209291842708, "KALETRA": 2.693984630671448, "KEPPRA": 1.0406053986882875, "KESIMPTA": 9.54347259262302, "KYMRIAH": 2.6902697229658705, "LEMTRADA": 28.243206903670345, "LEVETIRACETAM": 1.445608065313627, "LUTATHERA": 30.395794333192743, "MABCAMPATH": 28.46581378946015, "MABTHERA": 8.472184485878547, "MAVENCLAD": 245.25829444617733, "MERCAPTOPURINE": 6.794389196299509, "METHOTREXATE": 5.689556556870365, "MYCOPHENOLATE": 4.9875458444564815, "OLAPARIB": 14.303938738756528, "OLYSIO": 4.572777251010968, "PANTOPRAZOLE": 2.17658035063958, "PEGASYS": 1.0647979129969094, "PEGINTERFERON": 3.106132958839261, "PEMBROLIZUMAB": 1.4985251002634927, "PLEGRIDY": 11.701693174862449, "POTELIGEO": 62.31663035119141, "PRIVIGEN": 1.3085935381969536, "RIBAVIRIN": 3.032454403605515, "RINVOQ": 3.80303966770919, "RITUXIMAB": 5.878505093663969, "ROACTEMRA": 3.877571606952749, "RUXOLITINIB": 4.17910572908198, "STELARA": 1.4674944533639682, "STIVARGA": 1.6492357386854457, "TEMODAL": 16.68107467108862, "TEMOZOLOMIDE": 66.75238665159297, "TISAGENLECLEUCEL": 75.03930993327171, "TREMFYA": 2.0438324511174466, "XELJANZ": 1.2108075020017894, "ZELBORAF": 2.933488122200715, "ZERBAXA": 343.82570308638475, "ZYPREXA": 1.332036741665106}
\ No newline at end of file
+{"BINIMETINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5007.json
index a2cb0e32890..d5f2e4d2d42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5007.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5007.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 71.89894350936628, "ANAKINRA": 9.834574828168238, "AZATHIOPRINE": 19.26038188178627, "BUSULFAN": 17.796190320270146, "CELLCEPT": 25.38253063793229, "CICLOSPORIN": 34.304720264822684, "CIMZIA": 3.46824380424903, "GOLIMUMAB": 171.54023905889187, "METHOTREXATE": 37.01473173406536, "RITUXIMAB": 6.171210265561445, "SIMPONI": 5.8974497851605765, "XELJANZ": 1.9878502314571629}
\ No newline at end of file
+{"ENTYVIO": 46.55142795915202, "HUMIRA": 66.54237323532267, "null": 0.5086816374320208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5008.json
index 74c88ce329f..ae1664765a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5008.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5008.json
@@ -1 +1 @@
-{"null": 1.875690201927605}
\ No newline at end of file
+{"CICLOSPORIN": 9.94353305414932, "null": 1.5050909386456548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5009.json
index e901ccd7033..f3d421600e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5009.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5009.json
@@ -1 +1 @@
-{"null": 2.566265663764024}
\ No newline at end of file
+{"null": 1.7233708610319531}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/501.json
index df40bc379cf..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/501.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/501.json
@@ -1 +1 @@
-{"ADALIMUMAB": 18.698497387935017, "ENBREL": 250.2132357798923}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5010.json
index 573fd35adbb..1a5ad1a0399 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5010.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5010.json
@@ -1 +1 @@
-{"ARAVA": 1.9069808268651105, "COMBIVIR": 26.695846554904747, "EPIVIR": 33.722367037941495, "IBRANCE": 7.540550442395319, "LAMIVUDINE": 30.990901072345288, "MEPOLIZUMAB": 10.842457184564276, "PEGASYS": 3.1822239735592426, "null": 1.06473544483439}
\ No newline at end of file
+{"ALIMTA": 7.540149650996057, "ASPARAGINASE": 6.965564877225422, "AVASTIN": 10.718512787954406, "BEVACIZUMAB": 8.293772423064224, "CICLOSPORIN": 1.4048655049192322, "COMIRNATY": 0.165250004286143, "DEXAMETHASONE": 4.008444039687495, "DOCETAXEL": 5.148365347366503, "INCIVO": 11.24826156720184, "KEYTRUDA": 1.2751934304269388, "OLANZAPINE": 2.935893180135387, "ROTATEQ": 14.624890838600027, "SAXENDA": 5.953425285382934, "SUTENT": 1.4585973146845557, "VAXZEVRIA": 0.0625738431129526, "null": 1.9356760333840783}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5011.json
index 036a938ec4f..cb796c51058 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5011.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5011.json
@@ -1 +1 @@
-{"LACOSAMIDE": 51.73103555922069, "null": 2.715043369295507}
\ No newline at end of file
+{"null": 0.9761347316344936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5012.json
index 22514f5ccc8..d10790f6882 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5012.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5012.json
@@ -1 +1 @@
-{"null": 1.070559733320756}
\ No newline at end of file
+{"AIMOVIG": 5.593351118093032, "MEPOLIZUMAB": 15.228503661737228, "PANTOPRAZOLE": 16.603462478387588, "null": 1.1435787763530358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5013.json
index c57232a4ba2..0b81a13302d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5013.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5013.json
@@ -1 +1 @@
-{"null": 1.0073536249268118}
\ No newline at end of file
+{"COMIRNATY": 0.1333248892679253, "HUMIRA": 6.707212826314283, "KEYTRUDA": 4.802679667081652, "SUTENT": 3.127753383303937, "ZYPREXA": 3.0268398602898263, "null": 1.5061502170130654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5014.json
index 04785f405ad..a3527a8022c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5014.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5014.json
@@ -1 +1 @@
-{"SUBOXONE": 28.744040016204508, "null": 1.7708175590793294}
\ No newline at end of file
+{"ACETYLSALICYLIC": 50.74511261053413, "ADCIRCA": 4.7052299480691335, "AIMOVIG": 1.4674709247102389, "ARAVA": 0.8106412473117222, "AUBAGIO": 0.893242768992271, "BRAFTOVI": 1.6147600882472282, "BRINTELLIX": 2.3076452667621603, "CHAMPIX": 0.8566492669948065, "CIMZIA": 0.4691942620648712, "CLOPIDOGREL": 0.4548493742659287, "COMIRNATY": 1.4253550001009432, "COSENTYX": 1.7414620278334618, "CYMBALTA": 0.3247023246472617, "DEXAMETHASONE": 0.4717536994348486, "ELIQUIS": 0.806345516547755, "ENTRESTO": 0.5471294652044675, "ENTYVIO": 2.31231258260322, "ESBRIET": 0.9520182071909268, "EXJADE": 0.898711919131948, "FAMPYRA": 2.087319802945844, "FORSTEO": 1.116181254616537, "GARDASIL": 0.4291193688839598, "HUMIRA": 0.8834547492841732, "IBRANCE": 0.4698946381817677, "IBUPROFEN": 0.7516364208499599, "LIXIANA": 1.9593535279852288, "MODERNA": 0.5142450801671511, "NEXAVAR": 0.3583996103253956, "OFEV": 2.742896542182305, "PEGASYS": 0.1568481292620236, "PLAVIX": 0.4503295153768203, "ROACTEMRA": 0.8163048396688433, "SAXENDA": 1.9034547451489636, "SHINGRIX": 0.9701480978397546, "SPIKEVAX": 1.2396407073094438, "STELARA": 0.5912761200937514, "SUTENT": 0.6404648019240383, "TOZINAMERAN": 1.1846230623835314, "TRULICITY": 2.829708585882691, "VAXZEVRIA": 1.3345191294747665, "VICTOZA": 2.1805427462526974, "VOTRIENT": 0.745909227217837, "XELJANZ": 1.5426313897728137, "XOLAIR": 0.3860347492662845, "XTANDI": 0.5089525821708993, "null": 1.1432581409032114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5015.json
index 0fd2f1aaea9..30c8e2bb67e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5015.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5015.json
@@ -1 +1 @@
-{"ACE": 25.88607086778382, "ACETIC": 2094.342912544314, "ADALIMUMAB": 19.968526399944903, "ALIGN": 103.1497414299534, "AMINOSALICYLIC": 52.69591190606454, "ANORO": 1.4812074984599104, "APIDRA": 2.0058052895522818, "AVAMYS": 100.631583862083, "BEOVU": 2.753031074251332, "BUDESONIDE": 56.74452833179084, "BYDUREON": 1.5291862182484937, "BYETTA": 1.3673735926722022, "ELIQUIS": 2.644889694056368, "ERTAPENEM": 23.499619126453133, "EVISTA": 1.4319195827343758, "EYLEA": 6.596083476724825, "HUMALOG": 6.873135908429041, "HUMIRA": 1.503884537301245, "INCRUSE": 4.22004828739168, "INSULIN": 1.4846837434368003, "LANTUS": 7.950099283915953, "LEVEMIR": 4.952040199595427, "PLAVIX": 1.162565278942742, "REVATIO": 1.8561593924882127, "TOVIAZ": 1.7122049435448288, "TRELEGY": 2.61291106203906, "TRULICITY": 1.4737615699466828, "VIAGRA": 2.66454131234433, "XELJANZ": 1.0382362859232408, "ZOSTAVAX": 2.084731392308088}
\ No newline at end of file
+{"ALIMTA": 4.130067607171318, "ANAKINRA": 12.88716872677673, "ASPARAGINASE": 4.69816200492505, "AVASTIN": 93.50277957307928, "BEVACIZUMAB": 21.121010421757383, "CABOMETYX": 10.47796376931451, "CELLCEPT": 2.5427870518836264, "CICLOSPORIN": 1.07372855528153, "DEXAMETHASONE": 2.210527748430587, "INLYTA": 8.656871112969979, "IRESSA": 5.0569163625333, "KEYTRUDA": 10.034904563258438, "LENVIMA": 40.12790119771768, "NEXAVAR": 10.247663107593302, "OFEV": 4.392510452123849, "OPDIVO": 4.875137917493226, "RINVOQ": 24.585505658215705, "ROACTEMRA": 8.987047724134243, "STIVARGA": 30.192403927791126, "SUTENT": 5.37178977165879, "VECTIBIX": 16.415169105565433, "VOTRIENT": 7.039805241374208, "XELJANZ": 4.025802609356632, "null": 0.7387326588343253}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5016.json
index 63b2c82763a..5f69103914e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5016.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5016.json
@@ -1 +1 @@
-{"BRAFTOVI": 138.08795302806917, "JETREA": 1078.3765261200688}
\ No newline at end of file
+{"ELIQUIS": 18.783268778738822, "null": 0.4656970531888171}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5017.json
index ed7f400cb36..8b35a04f916 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5017.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5017.json
@@ -1 +1 @@
-{"AIMOVIG": 531.1042025712393}
\ No newline at end of file
+{"CLOPIDOGREL": 10.268531560226863, "ELIQUIS": 16.83178580021113, "PLAVIX": 18.222588473627383, "XARELTO": 50.88177702095466, "null": 0.6265361043973344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5018.json
index 04eed762b5f..49893e3acf0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5018.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5018.json
@@ -1 +1 @@
-{"EYLEA": 251.2185392333289}
\ No newline at end of file
+{"null": 1.3435687771524831}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5019.json
index e6ff2387744..6c82a22fe34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5019.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5019.json
@@ -1 +1 @@
-{"EYLEA": 133.99738726450923, "JETREA": 4742.731750220694, "LANTUS": 2.001171565263475, "VIAGRA": 12.44629385977021, "ZOSTAVAX": 5.734687094075265}
\ No newline at end of file
+{"ASPARAGINASE": 561.9550542438122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/502.json
index 32682fdf363..5563a162e95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/502.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/502.json
@@ -1 +1 @@
-{"ACLIDINIUM": 42.79248108704672, "ARANESP": 382.90548999125576, "SPIKEVAX": 4.841745469737655, "ZOSTAVAX": 37.13520669391215}
\ No newline at end of file
+{"null": 4.489626363644233}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5020.json
index fffd941429c..fc3edb78072 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5020.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5020.json
@@ -1 +1 @@
-{"ACTOS": 13.124275732943987, "APIDRA": 8.016697006377177, "AVANDAMET": 26.75152210463802, "AVANDIA": 50.570604294264726, "AVASTIN": 5.276359869718402, "BEOVU": 56.81511750917128, "BRAFTOVI": 13.476829963000965, "COTELLIC": 18.16314842919592, "EYLEA": 43.9068730243313, "HUMALOG": 4.321691850946753, "JETREA": 65.3759087378149, "LANTUS": 2.0776330519322554, "MEKINIST": 4.772524171679895, "MVASI": 49.39423957211921, "NEVANAC": 78.65877849794477, "PEGASYS": 1.3856567897250325, "VIAGRA": 9.445230570750857, "ZOSTAVAX": 1.1034088178498744}
\ No newline at end of file
+{"null": 0.6695999608341691}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5021.json
index 1b7baf91ee6..5630806938b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5021.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5021.json
@@ -1 +1 @@
-{"CELLCEPT": 2.3005229126089555, "CICLOSPORIN": 1.7601675007721844, "COSENTYX": 6.390419258282256, "DEXAMETHASONE": 3.737861339238013, "ELIQUIS": 1.100369293077037, "LEVOFLOXACIN": 6.507771537663624, "OPTIMARK": 2.802642456092703, "SUFENTANIL": 19.15446590647125, "SUTENT": 1.2305766681378087, "null": 1.8901707743996232}
\ No newline at end of file
+{"AIMOVIG": 2.1278386228190107, "CLOPIDOGREL": 1.284016509194265, "COMIRNATY": 0.241209870182077, "CYMBALTA": 1.830815214016554, "EXJADE": 2.2892227298083045, "IBUPROFEN": 5.882996192688777, "JANUMET": 2.745717497949153, "JARDIANCE": 0.9977201582790796, "LYRICA": 2.8219663282558787, "OFEV": 4.484790637477156, "OLANZAPINE": 5.160373831128488, "ROTATEQ": 18.05493430872045, "SPIKEVAX": 0.2021887662540474, "SUTENT": 1.1461082978652857, "TOZINAMERAN": 0.6019095711350252, "TRULICITY": 4.279817904951046, "VAXZEVRIA": 0.194784998315146, "ZYPREXA": 1.9673230189740047, "null": 2.404976181343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5022.json
index f1f52eae7a9..15b8a9f5be2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5022.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5022.json
@@ -1 +1 @@
-{"ARAVA": 2.0988054650031627, "EXJADE": 4.332810753745315, "EYLEA": 14.33417113903644, "HUMALOG": 2.8347756652507394, "SILDENAFIL": 17.732171691654205, "null": 1.6273772423960369}
\ No newline at end of file
+{"LIRAGLUTIDE": 194.37817882313828, "TEDUGLUTIDE": 827.8331164307498, "null": 1.338840423796911}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5023.json
index 7a0067a5708..f093ebfadcf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5023.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5023.json
@@ -1 +1 @@
-{"AUBAGIO": 9.249042440884208, "DEXAMETHASONE": 3.414606412778061, "DOCETAXEL": 28.634906865586395, "FASLODEX": 6.606045865529776, "HERCEPTIN": 20.146285544475266, "IBRANCE": 12.718244721351205, "KISQALI": 18.426697040160583, "SUTENT": 1.8513231368905756, "TOPOTECAN": 111.006133198286, "VOTRIENT": 3.754044316291969}
\ No newline at end of file
+{"TEDUGLUTIDE": 9535.860229578517, "null": 1.1414720922686423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5024.json
index ae666cd05af..142561d85f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5024.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5024.json
@@ -1 +1 @@
-{"SPIKEVAX": 16.14723547511517}
\ No newline at end of file
+{"null": 3.1525519358877845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5025.json
index 7942ad0d4c8..4db056d14a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5025.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5025.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 33.4308022293989, "AUBAGIO": 33.06925983358782, "BUPIVACAINE": 13.306867129314227, "CICLOSPORIN": 3.887643206601181, "FAMPYRA": 14.742149006259872, "LEMTRADA": 87.63845247378052, "METHOTREXATE": 4.132993204264399, "PLEGRIDY": 23.671488700767597, "VIGABATRIN": 215.38064940058064, "null": 1.1572049034453584}
\ No newline at end of file
+{"null": 0.502161135947256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5026.json
index 72380ab2550..209a4123d3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5026.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5026.json
@@ -1 +1 @@
-{"COVID19": 10.051137178476331, "SPIKEVAX": 3.9302928745301777}
\ No newline at end of file
+{"GLIVEC": 339.22883004376786, "IMATINIB": 254.6933176216501, "NEXAVAR": 2.679323249244824, "NILOTINIB": 11.736393193335884, "REGORAFENIB": 37.71499409464941, "STIVARGA": 29.829892794878464, "SUTENT": 210.4016494260949, "TASIGNA": 5.130809918818825, "null": 0.0864118779961921}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5027.json
index 8c1db396827..3567e569364 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5027.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5027.json
@@ -1 +1 @@
-{"ABACAVIR": 3.2284729614290035, "ANAKINRA": 10.20912020746489, "ASPARAGINASE": 15.214867007330565, "BEVACIZUMAB": 13.292326543312454, "CICLOSPORIN": 9.77919968973547, "CYMBALTA": 1.5350486267018928, "GARDASIL": 2.2496140464684977, "GLIBENCLAMIDE": 61.25440741479058, "KALETRA": 6.922696514695927, "LACOSAMIDE": 26.60207033401084, "VIGABATRIN": 1295.492678923104, "null": 1.1853633874689598}
\ No newline at end of file
+{"null": 1.1414720922686423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5028.json
index 4b8aaf40411..18e8608847b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5028.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5028.json
@@ -1 +1 @@
-{"SPIKEVAX": 15.60778192516601}
\ No newline at end of file
+{"null": 1.0720660417193746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5029.json
index 59cae665efa..eb31f982149 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5029.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5029.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0352893892793984, "MEPOLIZUMAB": 108.46702368418488, "SPIKEVAX": 6.649218182807665}
\ No newline at end of file
+{"ABATACEPT": 2.987268534119775, "ADALIMUMAB": 0.8807895480257865, "ALIMTA": 4.251609047365809, "ARAVA": 11.267423015570712, "AVASTIN": 12.023691216921158, "BEVACIZUMAB": 20.4935059291466, "BUSULFAN": 5.18185948912087, "CABOMETYX": 5.031319210647889, "CAPECITABINE": 25.06898519970581, "CARMUSTINE": 20.46131854364733, "CELLCEPT": 2.9013569700321047, "CIMZIA": 1.5176057566127956, "CYTARABINE": 3.6019455128828524, "DOCETAXEL": 8.472649627069885, "DOXORUBICIN": 5.511553625063246, "ENBREL": 17.68575744113546, "HUMIRA": 3.365072145680986, "IRINOTECAN": 38.51108397261213, "KEYTRUDA": 0.8765976705356187, "LONSURF": 8.75236664587835, "NEXAVAR": 1.573053001135691, "PAZOPANIB": 14.277915741464014, "PEMBROLIZUMAB": 4.178889296420048, "PEMETREXED": 15.46480298601168, "SUTENT": 1.8649243852989303, "VECTIBIX": 26.317986804612485, "VOTRIENT": 3.1475600789309914, "null": 0.4471283493309128}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/503.json
index 44c63d09ffd..51c7c31325b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/503.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/503.json
@@ -1 +1 @@
-{"null": 13.257198417882725}
\ No newline at end of file
+{"AIMOVIG": 0.8861922532615215, "ARIPIPRAZOLE": 0.4100717021029363, "AUBAGIO": 0.2049819682683155, "BENLYSTA": 0.2840505798259405, "BRINTELLIX": 0.6266308964995626, "BUSULFAN": 1.2202435198146984, "CARMUSTINE": 1.212046389536792, "CHAMPIX": 0.3981049662280641, "CIMZIA": 0.0577963912905304, "COMIRNATY": 12.263344567253128, "CYMBALTA": 0.1595225520056116, "DOCETAXEL": 0.6824084588289963, "ELLAONE": 2.275766905749496, "ERENUMAB": 2.744479301086959, "ESMYA": 17.975812491780623, "EVRA": 2.704875313116577, "GARDASIL": 1.319542693656402, "INSULIN": 0.159983550098055, "INVEGA": 7.892499593476063, "KEPPRA": 0.2624858458439495, "LATUDA": 0.4767764360778065, "METHOTREXATE": 0.1436419990055195, "MODERNA": 5.74424857538131, "OCRELIZUMAB": 0.3669656718140102, "OLANZAPINE": 0.7232758794191987, "PEGASYS": 0.0811559905028318, "REBIF": 3.167374425977623, "RINVOQ": 1.3516731083566311, "RISPERIDONE": 0.926465664088776, "RYEQO": 24.40258963306568, "SAXENDA": 0.3694080376040936, "SPIKEVAX": 1.989463228349584, "STELARA": 0.2065408067849976, "TOZINAMERAN": 0.738993188414561, "VAXZEVRIA": 0.5413505353336832, "XELJANZ": 0.0622256580909404, "XOLAIR": 0.0886460954830472, "ZYPREXA": 0.8983115768757141, "null": 0.2095835002451953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5030.json
index 2dd0e79304a..c8a8b66fe02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5030.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5030.json
@@ -1 +1 @@
-{"SPIKEVAX": 11.364666689149423}
\ No newline at end of file
+{"null": 1.416391468466869}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5031.json
index 910fb8bb81e..b84413610b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5031.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5031.json
@@ -1 +1 @@
-{"ABILIFY": 4.748040716114136, "ARIPIPRAZOLE": 1.2912542252672343, "BIKTARVY": 3.869531464238956, "BRINTELLIX": 5.2675713168562375, "CHAMPIX": 8.878504872299018, "CYMBALTA": 3.3690227382296243, "DULOXETINE": 7.223976878819252, "ESOMEPRAZOLE": 101.11756952010852, "GARDASIL": 2.5541108282856504, "IBUPROFEN": 2.253603958169095, "KEPPRA": 4.898458763041879, "LATUDA": 10.670326275528408, "LEVETIRACETAM": 4.97187036849143, "OLANZAPINE": 5.48732768183777, "OPTIMARK": 1.9910250709408768, "PEGASYS": 2.599668333410378, "PEGINTERFERON": 2.7815453689361043, "PEGINTRON": 1.1258618332135972, "SUBOXONE": 4.834075089151133, "TIVICAY": 16.01999119556906, "XELJANZ": 1.3606682519698727, "ZOSTAVAX": 8.639625671818244, "ZYPREXA": 3.316289176196924, "null": 1.68570890539775}
\ No newline at end of file
+{"COMIRNATY": 0.5538275711658625, "null": 1.2031938110405558}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5032.json
index b333e7ce80a..523f18bf14c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5032.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5032.json
@@ -1 +1 @@
-{"CELLCEPT": 2.306561090966368, "CICLOSPORIN": 1.0241629963027534, "FENTANYL": 1.1941684698667847, "JANUMET": 1.9533881780353917, "LATUDA": 2.478510551521283, "LEVETIRACETAM": 2.7857197542984866, "NOXAFIL": 10.608870916373665, "RINVOQ": 5.98398775184608, "null": 6.96587064876283}
\ No newline at end of file
+{"null": 2.1526103969026127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5033.json
index a8a9efb3d12..04be15b26e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5033.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5033.json
@@ -1 +1 @@
-{"null": 1.7025476302047156}
\ No newline at end of file
+{"null": 5.557101568430234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5034.json
index 914cb40f26f..150eacb30b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5034.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5034.json
@@ -1 +1 @@
-{"null": 4.300975156186353}
\ No newline at end of file
+{"BIKTARVY": 83.8861499345394, "CYMBALTA": 11.168444030045542, "DESCOVY": 103.9029424781775, "ELIQUIS": 6.062361877880409, "GENVOYA": 52.6857427621192, "ISENTRESS": 67.11132867204128, "JANUMET": 11.81918114799445, "JANUVIA": 14.237684525825111, "KEPPRA": 2.2549236967474333, "KEYTRUDA": 1.7008183915558637, "MIMPARA": 167.58058502170368, "NOXAFIL": 16.854719342134363, "OPSUMIT": 3.634211268457672, "REYATAZ": 25.148317704360064, "TRACLEER": 7.879626722451301, "TRUVADA": 0.8211407405146665, "null": 0.6748357690362168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5035.json
index b7b782f831e..7af8cbaa4f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5035.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5035.json
@@ -1 +1 @@
-{"HUMALOG": 48.65424171960977}
\ No newline at end of file
+{"BUDESONIDE": 5.326384884646954, "CLOPIDOGREL": 4.467539541741807, "ELIQUIS": 1.5723968827119446, "ENTYVIO": 17.22851839635191, "PLAVIX": 10.107347258778518, "null": 1.321064875315441}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5036.json
index c596aea496a..52552203d68 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5036.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5036.json
@@ -1 +1 @@
-{"ALDARA": 1.1594393735722135, "ALIGN": 2.201146362300357, "AMINOSALICYLIC": 1.2538474459840692, "BAVENCIO": 1.0046803391494987, "BENRALIZUMAB": 1.320200257930096, "CABOMETYX": 1.0419771953095909, "CERVARIX": 1.800453978852989, "COMIRNATY": 2.6422687249103607, "COVID19": 2.622014177443229, "DUAKLIR": 1.2793781400733302, "FENDRIX": 1.334341218908643, "FLEBOGAMMA": 1.1649953504088917, "FLUCELVAX": 1.6318172648695004, "INFLECTRA": 1.2739916066427956, "INTRONA": 1.2634048789659182, "JCOVDEN": 1.7204632835107283, "JEVTANA": 1.1324254293910134, "KALYDECO": 1.5220188525607954, "LENVIMA": 1.8002963535296217, "LYNPARZA": 1.0606872096734314, "MMRVAXPRO": 1.153548011385216, "NIMENRIX": 2.159207342977912, "OMALIZUMAB": 1.2320210568292609, "PIRFENIDONE": 1.418455425362824, "PROLIA": 1.308916280146167, "RAPISCAN": 1.1185317536438044, "REMSIMA": 1.8193140358185047, "SEMAGLUTIDE": 2.942363592521839, "SHINGRIX": 1.204634645974758, "SIMPONI": 1.3092059485441914, "SPIKEVAX": 3.146917849081165, "TERROSA": 1.2151780935480594, "VAXZEVRIA": 1.7236754462446675, "ZIAGEN": 2.2343565591019785}
\ No newline at end of file
+{"CLOPIDOGREL": 29.40992060296735, "ELIQUIS": 17.478570163171543, "PLAVIX": 29.11766531041668, "null": 0.9029617895825538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5037.json
index 47afa6c60d2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5037.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5037.json
@@ -1 +1 @@
-{"CELSENTRI": 314.199920891648, "COMBIVIR": 60.12535236189317, "null": 2.0212289754145263}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5038.json
index 47f3b2ff7c6..6d0f5db3247 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5038.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5038.json
@@ -1 +1 @@
-{"null": 4.934436336095037}
\ No newline at end of file
+{"CLOPIDOGREL": 13.650483203155051, "ELIQUIS": 7.453626206016144, "PLAVIX": 63.68724138512445, "XARELTO": 113.62537844237836, "null": 0.338080293447027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5039.json
index bfd07aa29d0..4c3916786a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5039.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5039.json
@@ -1 +1 @@
-{"VIAGRA": 52.14127593129213, "null": 6.265623095496101}
\ No newline at end of file
+{"null": 0.7179149906336206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/504.json
index 22eb35e5b43..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/504.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/504.json
@@ -1 +1 @@
-{"null": 1.5423794178557078}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5040.json
index 9c9d9001a72..460ec8d92e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5040.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5040.json
@@ -1 +1 @@
-{"VIAGRA": 33.506478751547284, "null": 3.223244446764583}
\ No newline at end of file
+{"ADCIRCA": 60.44190481972753, "CYTARABINE": 10.942681602711453, "ENTYVIO": 24.160542691650825, "JANUMET": 16.066529292699062, "SPIKEVAX": 0.292124163868785, "SUTENT": 1.7430990355602496, "null": 0.5066490891291334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5041.json
index 524bf959f30..2d0031b9f9b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5041.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5041.json
@@ -1 +1 @@
-{"null": 3.7249674127896375}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5042.json
index 8ec153407f8..f799fc55292 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5042.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5042.json
@@ -1 +1 @@
-{"null": 1.3092049495297184}
\ No newline at end of file
+{"null": 3.839799338917061}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5043.json
index bfeaf97ecf0..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5043.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5043.json
@@ -1 +1 @@
-{"AFINITOR": 10.65652931067766, "BYETTA": 77.72463427589034, "JANUMET": 28.83186335285856, "KEYTRUDA": 15.44114488723946, "NEXAVAR": 9.704594799694252}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5044.json
index d6638b7cc3d..952df66681c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5044.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5044.json
@@ -1 +1 @@
-{"VOTRIENT": 1165.1732247638752}
\ No newline at end of file
+{"null": 4.005218844184789}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5045.json
index 9ae3cdeeb51..75f2a68cc29 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5045.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5045.json
@@ -1 +1 @@
-{"CANNABIDIOL": 6173.011979038408}
\ No newline at end of file
+{"BIKTARVY": 39.71666788395807, "CYMBALTA": 4.543903209582577, "ELIQUIS": 5.705676108752737, "GENVOYA": 58.36946654505461, "ISENTRESS": 37.41306126457084, "JANUMET": 11.848902034024205, "JANUVIA": 13.692366248616723, "MIMPARA": 155.17940999063666, "SYNAGIS": 16.171757107267304, "ZAVESCA": 255.98396991124983, "null": 0.8862324887850251}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5046.json
index 3d9f9686ea6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5046.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5046.json
@@ -1 +1 @@
-{"CICLOSPORIN": 43.63452627638474}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5047.json
index 4b0541a609e..e631993b193 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5047.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5047.json
@@ -1 +1 @@
-{"KEYTRUDA": 40.06616746239568}
\ No newline at end of file
+{"null": 0.8747763506310584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5048.json
index 4db24cd6242..ca3e51a48a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5048.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5048.json
@@ -1 +1 @@
-{"ARAVA": 1.199566424943329, "SOLIRIS": 23.650686245210693}
\ No newline at end of file
+{"ARIPIPRAZOLE": 3.354433281552398, "COMIRNATY": 0.4183906518721478, "CYMBALTA": 0.8047580386836274, "FYCOMPA": 27.749640592152737, "GARDASIL": 4.161020548772105, "INFANRIX": 16.670475127604053, "MMRVAXPRO": 15.768668091530634, "NIMENRIX": 4.665709502045421, "OLANZAPINE": 3.189187351206502, "PREVENAR": 32.192489975390544, "SPIKEVAX": 0.4595754595909315, "VAXZEVRIA": 0.076632398955177, "ZYPREXA": 2.1670657168287693, "null": 2.946459253745713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5049.json
index f63c110b8a4..6cf6bf77fc7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5049.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5049.json
@@ -1 +1 @@
-{"AVAMYS": 321.4682757996754}
\ No newline at end of file
+{"null": 1.4737406591636295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/505.json
index 522958fe4da..5c5f3481e08 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/505.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/505.json
@@ -1 +1 @@
-{"AMIKACIN": 38.4740518413227, "CLOPIDOGREL": 2.086849182284414, "CYMBALTA": 2.1281337990657474, "ELIQUIS": 1.1388812148761325, "XARELTO": 13.327564404483804, "null": 5.7675993332376985}
\ No newline at end of file
+{"CICLOSPORIN": 40.11724168797738, "null": 0.352382957625774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5050.json
index 43cfe36196a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5050.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5050.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 1.2353803266416474, "AUBAGIO": 1.1377122318913655, "BINIMETINIB": 46.72571709494515, "BRAFTOVI": 3.245991038295499, "BYDUREON": 2.6930509632110757, "CELLCEPT": 1.6722198047409131, "CIALIS": 1030.757229570867, "CICLOSPORIN": 1.012835720774219, "CIMZIA": 1.3081235548548542, "COSENTYX": 2.524605838198359, "COTELLIC": 5.734243465443444, "DABRAFENIB": 62.77887682052799, "ENBREL": 2.276871814387254, "ENTYVIO": 1.9579660411861453, "FAMPYRA": 1.325981675031297, "HUMIRA": 2.1377954818542277, "IPILIMUMAB": 2.930529179041703, "JAKAVI": 1.1249545095300957, "LEMTRADA": 2.0770975811767176, "LEVITRA": 100.69410941559936, "MEKINIST": 64.03054324406182, "MYCOPHENOLATE": 2.360610977139317, "NPLATE": 1.299167524313558, "REMICADE": 4.3288275580812, "RINVOQ": 3.870643412967511, "ROACTEMRA": 6.834719714660357, "SILDENAFIL": 10.874259051185092, "SIMPONI": 4.127388079783122, "STELARA": 8.22177690420082, "TADALAFIL": 27.122319976752102, "TAFINLAR": 26.51803200313268, "TREMFYA": 3.0973226128390805, "VALSARTAN": 4.812103877481853, "VIAGRA": 186.55452091965492, "XELJANZ": 2.5408563090460943, "XOLAIR": 2.1604329481759623, "YERVOY": 2.4404107321332678, "ZELBORAF": 22.42615015582018, "ZOSTAVAX": 1.04114112994158}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5051.json
index dfc1fa9ceec..d2cb816199f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5051.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5051.json
@@ -1 +1 @@
-{"CIALIS": 2984.2853286942864, "CIMZIA": 1.1744718761862172, "LEVITRA": 326.721474720663, "STELARA": 6.499803782123895, "VIAGRA": 304.06768829500163}
\ No newline at end of file
+{"ABRAXANE": 91.3961623391678, "AZACITIDINE": 22.397063404129423, "BEVACIZUMAB": 13.106333568065692, "CYTARABINE": 7.588635848261394, "DARUNAVIR": 57.80395433588703, "DEXAMETHASONE": 10.444869816058512, "GEFITINIB": 76.17624291310764, "IMATINIB": 62.43513421369017, "IRESSA": 30.909304431817933, "IRINOTECAN": 18.48866461171893, "SOLIRIS": 18.91004049148605, "SPRYCEL": 30.12755491850753, "null": 0.2898855303214103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5052.json
index 630f84936a8..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5052.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5052.json
@@ -1 +1 @@
-{"CIALIS": 10055.556989065251, "VIAGRA": 74.9636904094196}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5053.json
index ff2271e02e5..bb0a3df184a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5053.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5053.json
@@ -1 +1 @@
-{"CIALIS": 6699.82115394077, "VIAGRA": 108.97182328947208}
\ No newline at end of file
+{"GLIVEC": 112.40264336280148, "STRIBILD": 16.558650560064695, "TASIGNA": 96.45183951585608, "TRUVADA": 4.908400027954089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5054.json
index c0e33819630..b868b424c59 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5054.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5054.json
@@ -1 +1 @@
-{"CIALIS": 3313.018374028092, "MEKINIST": 54.38052734536953, "VIAGRA": 115.61467380398553}
\ No newline at end of file
+{"null": 3.521488923428598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5055.json
index bb23ec1e96c..456d2f2b964 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5055.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5055.json
@@ -1 +1 @@
-{"CIALIS": 2615.4602735927106, "DABRAFENIB": 110.14107887544486, "MEKINIST": 182.9944745065283, "VIAGRA": 116.42887587058576}
\ No newline at end of file
+{"null": 1.1321470499715232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5056.json
index e038d5d3b36..9375616b082 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5056.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5056.json
@@ -1 +1 @@
-{"JANUMET": 64.55445316299304}
\ No newline at end of file
+{"ARAVA": 0.3052187843969478, "CLOPIDOGREL": 0.9829497200401336, "COMIRNATY": 0.3580749159730921, "COSENTYX": 1.1236217250516218, "CYMBALTA": 0.9164638946558872, "ENTRESTO": 4.123896193324312, "EXFORGE": 4.07628895957286, "EXJADE": 3.273542237884899, "FORSTEO": 1.4588758325294031, "HUMALOG": 1.2670605290825692, "JAKAVI": 6.985947192479478, "KEYTRUDA": 0.8439854027639777, "LANTUS": 0.8590999964390493, "MEPOLIZUMAB": 3.011572200364233, "OMALIZUMAB": 5.3275421019367855, "PEGASYS": 0.7345658516511685, "SIMPONI": 4.180621706128001, "SPIKEVAX": 0.2270255812846612, "SUTENT": 1.866548161425852, "TRACLEER": 2.351162456505008, "VAXZEVRIA": 0.1312134117906591, "XOLAIR": 1.987024445050661, "XTANDI": 1.8992604762514973, "ZYPREXA": 1.0733810163864317, "null": 1.1988733613210776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5057.json
index 6562b92465e..baf26548d37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5057.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5057.json
@@ -1 +1 @@
-{"KEYTRUDA": 42.14701765866408}
\ No newline at end of file
+{"ABACAVIR": 0.1289856425077028, "ABATACEPT": 4.220113954313813, "ABILIFY": 0.5136490317322261, "ACLASTA": 3.7396188839798192, "ACTRAPID": 1.554510731556478, "ADALIMUMAB": 6.285846972803346, "ADCIRCA": 1.3897022597215554, "ADEMPAS": 0.6157006824355197, "ADENURIC": 1.1404089733424638, "ADVAGRAF": 2.3728861876467917, "AERIUS": 0.8743766346335468, "AFINITOR": 2.4687783191896284, "AIMOVIG": 0.2530617904396872, "ALEMTUZUMAB": 0.2795524645132208, "ALIMTA": 3.3219538157415496, "AMIKACIN": 1.22793575965664, "AMINOSALICYLIC": 1.7155267351689745, "APIDRA": 0.4768021008446139, "APIXABAN": 0.557204771663901, "APREMILAST": 5.652607483802892, "APREPITANT": 12.675750125958908, "APROVEL": 0.7360122323499679, "ARANESP": 11.249111382868575, "ARAVA": 3.724033325652897, "ARIPIPRAZOLE": 0.8070348575845119, "ASPARAGINASE": 0.8049131905236733, "ATAZANAVIR": 0.4774721984991534, "ATEZOLIZUMAB": 1.5192459123341393, "ATRIPLA": 0.3539797465366559, "AUBAGIO": 0.6212461199018467, "AVAMYS": 0.1364383536215296, 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"RAPAMUNE": 1.6995232974542238, "RASBURICASE": 8.370152932510361, "RASILEZ": 1.0399622014944, "REBETOL": 1.4606419440057112, "REGORAFENIB": 3.087177415854483, "RELVAR": 0.7695845920782091, "REMDESIVIR": 2.354658961441206, "REMICADE": 0.8457731861245346, "REVATIO": 1.038714569764014, "REVLIMID": 0.7958096074617107, "RIBAVIRIN": 0.6098572521564476, "RIBOCICLIB": 0.7360495655276544, "RINVOQ": 0.8358213859699252, "RISPERIDONE": 1.0959582116200934, "RITUXIMAB": 1.3682968498086006, "ROACTEMRA": 0.8780143020336854, "ROTATEQ": 1.0269807502099857, "RUBRACA": 0.6002658434201072, "RUXOLITINIB": 1.2228429926977331, "SHINGRIX": 0.8658766660677968, "SIFROL": 1.8719111781795603, "SILDENAFIL": 1.7231466423043345, "SIMPONI": 0.379639333290913, "SOLIRIS": 1.6881430215989668, "SORAFENIB": 1.4533973190410678, "SOVALDI": 0.4964823000253649, "SPIKEVAX": 0.4610029989919891, "SPINRAZA": 1.8134478750515584, "SPIRONOLACTONE": 1.154387701456537, "SPRYCEL": 0.7618389720380799, "STALEVO": 3.102061139066422, "STELARA": 0.3731279499993423, "STIVARGA": 2.7473036898688576, "STRIBILD": 0.3126492207820143, "SUBOXONE": 0.2057078756099805, "SUSTIVA": 3.373776232891266, "SUTENT": 1.617287130010736, "SYNAGIS": 1.55279426831822, "TAFINLAR": 2.256908028393501, "TAGRISSO": 1.7550839007064245, "TAMIFLU": 0.5978553198425962, "TASIGNA": 0.7442409055221543, "TELMISARTAN": 1.2401447626987343, "TEMODAL": 1.483428776739043, "TEMOZOLOMIDE": 1.1274073693703557, "THALIDOMIDE": 1.1059991610898607, "TOBRAMYCIN": 1.7143184097250124, "TOPOTECAN": 1.0533238438661254, "TORISEL": 3.765928004252657, "TOVIAZ": 0.5827634451090656, "TOZINAMERAN": 0.1739477134986488, "TRACLEER": 1.6633232619512368, "TRELEGY": 0.3314612388128952, "TREMFYA": 0.304255929907499, "TRODELVY": 3.293896312853976, "TRULICITY": 0.6150332888187044, "TRUVADA": 0.3491338055915622, "TWINRIX": 1.6655228403146731, "VALSARTAN": 0.6470296861262873, "VAXZEVRIA": 0.2244192298301898, "VECTIBIX": 1.438102444862371, "VEKLURY": 1.592033890462808, "VELTASSA": 0.4938872896369952, "VEMURAFENIB": 2.1638242702828627, "VENCLYXTO": 3.713192362780255, "VENETOCLAX": 1.908762819626015, "VFEND": 1.070543254083685, "VIAGRA": 0.2415047940507007, "VICTOZA": 0.3409947482292112, "VIMPAT": 0.2905941064526655, "VIREAD": 0.6777394347541401, "VORICONAZOLE": 0.4844815453127297, "VORTIOXETINE": 3.142239720835997, "VOTRIENT": 1.6504960874054155, "XALKORI": 1.7141064119241805, "XARELTO": 0.5115748872348992, "XELJANZ": 0.4061430990503187, "XELODA": 0.9895052782718736, "XOFIGO": 19.88394878925993, "XOLAIR": 0.8340337365780012, "XTANDI": 2.547642216100543, "YERVOY": 2.561426451371126, "ZAVESCA": 4.599047971530279, "ZELBORAF": 1.30685236833259, "ZOSTAVAX": 0.1257160180513508, "ZYPREXA": 0.562212618405522, "null": 0.6831474010061677}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5058.json
index cbc60adae9f..b01911d121c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5058.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5058.json
@@ -1 +1 @@
-{"ABEMACICLIB": 17.71103368606872, "ABIRATERONE": 9.80531146295762, "ABRAXANE": 23.199986162423457, "ADCETRIS": 2.500141335478064, "AFATINIB": 10.974094265330796, "AFINITOR": 28.992812975770253, "AFLIBERCEPT": 4.271566426015454, "ALECTINIB": 15.509173382992389, "ALIMTA": 22.685301763025528, "ALPELISIB": 22.57815466307848, "APALUTAMIDE": 5.112240598587916, "ATEZOLIZUMAB": 4.695144332190645, "AVASTIN": 4.947617691044979, "AXICABTAGENE": 1.3611264431597094, "AXITINIB": 19.186621125061976, "AZACITIDINE": 2.0528288742589726, "BEVACIZUMAB": 8.337986541308332, "BINIMETINIB": 9.035119602991468, "BLINATUMOMAB": 3.878533800941676, "BORTEZOMIB": 2.1469346685459314, "BOSUTINIB": 3.751758454889652, "BRAFTOVI": 2.8503229898888818, "BRENTUXIMAB": 12.169908275871409, "BREYANZI": 11.064216574603396, "CABAZITAXEL": 23.794316321203663, "CABOMETYX": 14.663837198358197, "CABOZANTINIB": 23.020014512618467, "CAELYX": 3.0948885531340853, "CALCIUM": 9.729671495002776, "CAPECITABINE": 12.50883496228145, "CAPRELSA": 2.1683079265871723, "CARMUSTINE": 2.3766976935474866, "CERITINIB": 14.594242325161998, "CETUXIMAB": 7.610465091458724, "CLOFARABINE": 2.6297882588930475, "COBIMETINIB": 4.469167450252903, "CRIZOTINIB": 19.025366267636603, "CYRAMZA": 30.20567096301881, "CYTARABINE": 2.149678733019357, "DABRAFENIB": 33.366863067596874, "DASATINIB": 7.228553289343166, "DENOSUMAB": 8.211590523692863, "DEXAMETHASONE": 1.3650337827714318, "DOCETAXEL": 6.961275829144909, "DOXORUBICIN": 2.241303624174718, "DURVALUMAB": 12.685740063035697, "EMPLICITI": 10.47792816281476, "ENFORTUMAB": 16.821220033149324, "ENZALUTAMIDE": 18.53751142033012, "EPCORITAMAB": 3.0098643443827173, "ERBITUX": 6.81441490555122, "ERIBULIN": 16.817078574147903, "ERLOTINIB": 25.191557150446386, "EVEROLIMUS": 24.097942047331514, "EXJADE": 4.078279143019933, "FASLODEX": 18.001415794422723, "FILGRASTIM": 1.414135716161394, "FOTIVDA": 4.415054407236185, "FULVESTRANT": 24.749582372148613, "GEFITINIB": 51.87421790053863, "GIOTRIF": 9.972907481194987, "GLIVEC": 16.61708138935664, "HALAVEN": 12.269189941285596, "HYCAMTIN": 1.5812738244707236, "IBRUTINIB": 1.6070661621289557, "IMATINIB": 16.41465427309384, "IMFINZI": 5.664032268194773, "INLYTA": 2.3582650129712976, "IPILIMUMAB": 27.755525810245462, "IRESSA": 24.02795548612873, "IRINOTECAN": 5.222260454482672, "JAKAVI": 1.592226987887983, "JEVTANA": 2.209448956152972, "KEYTRUDA": 34.96939152703957, "KISQALI": 11.123173098770913, "KYMRIAH": 16.231291541400513, "LENALIDOMIDE": 3.256936199165221, "LENVATINIB": 10.076448626612216, "LENVIMA": 7.298647799365376, "LEUPRORELIN": 8.509482013205686, "LIBTAYO": 3.3511231171771247, "LONSURF": 5.398532703412329, "LUTATHERA": 11.689206230877357, "LUTETIUM": 7.052373895510567, "LYNPARZA": 21.829110716766078, "LYSODREN": 7.1671120220053, "MABCAMPATH": 2.2952875163023787, "MEKINIST": 21.414420371112428, "MIDOSTAURIN": 6.537038938722183, "MITOTANE": 16.095815953969478, "NERLYNX": 3.3445778904472245, "NILOTINIB": 7.997743830252789, "NIVOLUMAB": 16.770999437033964, "NUBEQA": 2.028595623473497, "OCTREOTIDE": 6.346768049164015, "OFATUMUMAB": 7.042521180092629, "OLAPARIB": 20.91696188034176, "OPDIVO": 25.993291592963157, "OSIMERTINIB": 46.0742427092143, "PACLITAXEL": 9.224935846706318, "PALBOCICLIB": 4.67972848222079, "PAZOPANIB": 38.95369816501778, "PEGFILGRASTIM": 1.1145666421555531, "PEMBROLIZUMAB": 22.544986335850417, "PEMETREXED": 20.37061834568109, "PIQRAY": 10.087116948684503, "PLUVICTO": 16.76075496028068, "QARZIBA": 8.80731004006506, "RIBOCICLIB": 17.327820122738164, "RITUXIMAB": 1.3113413979271882, "RUBRACA": 18.765646195545816, "RUXOLITINIB": 3.025916556907649, "RYDAPT": 3.180868996190057, "SORAFENIB": 2.809789132493224, "SPRYCEL": 11.37571149675828, "SUNITINIB": 4.075736551178736, "TAFINLAR": 10.074603566996371, "TAGRISSO": 23.07686060217942, "TASIGNA": 4.4327934507756375, "TAXOTERE": 2.4246877508444062, "TEGAFUR": 2.341822028937473, "TEMODAL": 3.859162467647848, "TEMOZOLOMIDE": 9.587188952169704, "THIOTEPA": 1.5404932203128563, "TISAGENLECLEUCEL": 2.229553208403124, "TOPOTECAN": 6.125014988030871, "TRAMETINIB": 25.4187534355958, "TRASTUZUMAB": 2.757867358889308, "TRISENOX": 1.6940306376611938, "VEMURAFENIB": 2.600347477976096, "VOTRIENT": 13.28520716586008, "XELODA": 1.0850365834327422, "XGEVA": 7.224431708774694, "XOFIGO": 3.833058014482327, "XTANDI": 33.76219057946895, "YERVOY": 52.809348812424254, "ZELBORAF": 1.1677659782070355, "ZOLEDRONIC": 7.868406437144278, "ZOMETA": 5.594598733873204}
\ No newline at end of file
+{"AMGEVITA": 636.8802479283545, "ARAVA": 1.11717094566097, "COMIRNATY": 0.1970067393063031, "CRIXIVAN": 32.72172983031557, "ENTYVIO": 7.0341645449440815, "FAMPYRA": 11.958999521844198, "GARDASIL": 3.753457570897822, "HUMIRA": 10.789202509719487, "LEFLUNOMIDE": 35.438560814111035, "RINVOQ": 10.9416287543033, "SPIKEVAX": 0.2037575550254365, "VAXZEVRIA": 0.258390777462638, "null": 1.4549304329713493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5059.json
index 7bbd5298010..03fc377245e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5059.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5059.json
@@ -1 +1 @@
-{"JANUVIA": 17.584144466350097}
\ No newline at end of file
+{"AVAMYS": 9.112878387719496, "COMIRNATY": 0.1565138750239079, "CYMBALTA": 2.8122520296477576, "GARDASIL": 12.27009129444493, "LYRICA": 5.570319794721856, "OLANZAPINE": 5.024108968046135, "ZOSTAVAX": 18.16937278298062, "ZYPREXA": 3.138172305162715, "null": 1.8584406197589136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/506.json
index 9b9f6ad961c..d590971dccf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/506.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/506.json
@@ -1 +1 @@
-{"null": 3.442512862192141}
\ No newline at end of file
+{"COMTAN": 287.49336409222485, "OLANZAPINE": 48.02189748962015, "null": 1.2412694206715336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5060.json
index 2800611dc1a..6b2b9d485d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5060.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5060.json
@@ -1 +1 @@
-{"AFINITOR": 14.9870654855149, "ALIMTA": 11.283119446394767, "CABOMETYX": 13.35405582847828, "EVEROLIMUS": 45.353502992322944, "FASLODEX": 20.49817889622529, "FULVESTRANT": 14.244076771502511, "IBRANCE": 4.226978430617154, "IRESSA": 29.596189572494023, "KEYTRUDA": 16.60076339480707, "MEKINIST": 9.124079053679669, "NEXAVAR": 7.209523246523186, "OPDIVO": 7.970671401605895, "SUTENT": 2.0739808227013725, "TAGRISSO": 16.791500949232315}
\ No newline at end of file
+{"null": 2.234965918179927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5061.json
index 290dd5c1c8b..4fa37ce7167 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5061.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5061.json
@@ -1 +1 @@
-{"GEFITINIB": 2091.4869565741496, "OSIMERTINIB": 887.0728703677532}
\ No newline at end of file
+{"ADALIMUMAB": 0.643060995923643, "AFINITOR": 2.87763109881739, "ALIMTA": 3.466945943486511, "APIDRA": 1.2959432761733116, "APIXABAN": 0.4935016467770273, "ARANESP": 0.6752290606707211, "ARAVA": 0.4519952425173443, "AVANDIA": 3.16527752348487, "BARACLUDE": 4.167501468500933, "BEDAQUILINE": 2.073654900839456, "BINOCRIT": 20.58629853871493, "BUDESONIDE": 1.7634614996472344, "BUMETANIDE": 6.6065137159538185, "BUSULFAN": 1.916716302890045, "BYETTA": 1.398000556769175, "CELLCEPT": 1.0479641440415302, "CHAMPIX": 0.7406642046340125, "CICLOSPORIN": 2.91330206027636, "CIMZIA": 1.409150388564306, "CLOPIDOGREL": 0.3419564289377835, "COMIRNATY": 0.2707466543905798, "COSENTYX": 0.4330429408784715, "CYMBALTA": 0.3913332396038771, "DEXAMETHASONE": 0.9110282332817043, "DOCETAXEL": 0.8259053282440714, "ELIQUIS": 0.2068525279760165, "ENBREL": 0.3534201566250747, "ENTRESTO": 1.7975932771046856, "EXFORGE": 5.260750835741959, "EXJADE": 1.7591404868798526, "FASENRA": 2.1056420776481617, "FENTANYL": 0.6519005515499794, "FORSTEO": 0.6176919872071873, "GALVUS": 3.3993588128725567, "GARDASIL": 0.3022144330749463, "GLIVEC": 8.991406170302016, "HERCEPTIN": 1.7850168853911632, "HUMALOG": 0.8117177299605873, "IBUPROFEN": 1.2818374575286169, "IMATINIB": 11.544894269482665, "INCIVO": 1.5671580401076284, "INSULIN": 2.006434879007469, "IRON": 4.6298974405027336, "JAKAVI": 0.7489407493533616, "JANUMET": 1.5568671042387814, "JANUVIA": 1.9492991620302316, "KALETRA": 0.932771174879452, "KEPPRA": 0.5243644627446981, "KEYTRUDA": 0.959362049200982, "LANTUS": 1.5769679496837858, "LENVIMA": 2.045157432292528, "LEVETIRACETAM": 1.6002785678214135, "LONSURF": 1.824666546541192, "LYRICA": 1.2518633299820705, "MICARDIS": 2.371044971549952, "NEXAVAR": 0.8846490426650884, "OLANZAPINE": 0.930988015676923, "OPSUMIT": 2.2567136023540724, "OPTIMARK": 0.6867741382528265, "PEGASYS": 1.0643699619617046, "PEGINTERFERON": 1.35613266441564, "PEGINTRON": 1.379909308548417, "PEMBROLIZUMAB": 1.550679097972672, "PLAVIX": 0.4120467011388892, "RASILEZ": 5.463655145441369, "REVATIO": 1.5274949900926749, "ROACTEMRA": 1.151813423840799, "SILDENAFIL": 1.9244333175046904, "SIMPONI": 0.3456167650683432, "SOLIRIS": 1.041677036985716, "SPIKEVAX": 0.154606632734482, "SPRYCEL": 3.0215952709851184, "STIVARGA": 0.6829489533085487, "SUBOXONE": 0.7637926384341058, "SUTENT": 2.3740404485798194, "TASIGNA": 1.856594541452772, "TOVIAZ": 1.9050958341723532, "TOZINAMERAN": 0.1419503435650525, "TRACLEER": 3.744146053088675, "VAXZEVRIA": 0.0993125138952729, "VFEND": 1.5470429670089627, "VOTRIENT": 1.7770227125199574, "XALKORI": 4.499413095760138, "XELJANZ": 0.247986435819727, "XOLAIR": 0.848470995150603, "XTANDI": 1.3566593936306872, "ZYPREXA": 1.7092444533663451, "null": 1.5202168744821565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5062.json
index 11d8b27a1c6..6b390e910bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5062.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5062.json
@@ -1 +1 @@
-{"ADCIRCA": 62.22821080783974, "CLOPIDOGREL": 10.865425450974785, "ELIQUIS": 4.41867178875727, "PEGINTRON": 5.054866311248769, "PLAVIX": 10.190047385489, "SUTENT": 2.76989674079206, "null": 1.1885480153518146}
\ No newline at end of file
+{"null": 1.6237216251425384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5063.json
index 56d3f6a04fc..5e9ad39a7c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5063.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5063.json
@@ -1 +1 @@
-{"ABILIFY": 1.2712984304546169, "AFINITOR": 1.672241098084206, "AMINOSALICYLIC": 2.553992999526739, "ARANESP": 1.3473128163952552, "ASPARAGINASE": 3.4388681663165293, "AVASTIN": 1.8307146499449176, "BUDESONIDE": 1.080773542369649, "BUPRENORPHINE": 1.5534160130250032, "BYETTA": 7.607901465940682, "CLOPIDOGREL": 1.947431986615608, "ENTYVIO": 3.182103693668411, "ESOMEPRAZOLE": 6.876028483988614, "EXJADE": 1.941364876810888, "FIRDAPSE": 11.32959981765502, "HUMALOG": 10.113088864055069, "HUMIRA": 3.149603411883763, "INLYTA": 1.7284998685634814, "INSULIN": 2.1410576600848086, "JANUMET": 3.807384667278464, "JANUVIA": 6.5371979951144406, "KEYTRUDA": 1.1027523424868009, "LACOSAMIDE": 4.413136517393929, "LANTUS": 1.5764929783126402, "METHOTREXATE": 1.266283054638143, "MIMPARA": 6.854318975706754, "NPLATE": 6.010383354639162, "OPSUMIT": 1.3453713516308852, "PEGASYS": 1.0345589417147654, "PEGINTRON": 2.100944198813491, "PLAVIX": 1.2824053567639242, "PRADAXA": 9.52112891603238, "RUBRACA": 4.121488334961979, "SOLIRIS": 1.2915249332766965, "SPINRAZA": 15.777376221445708, "STELARA": 2.0192239115484565, "STIVARGA": 1.726361786020384, "SUTENT": 1.94350622051573, "VOTRIENT": 1.3617120526091426, "XTANDI": 1.2656585040548949, "ZOSTAVAX": 1.1278568769518682, "ZYPREXA": 1.854527958506844}
\ No newline at end of file
+{"ABACAVIR": 0.1352463580312196, "ABILIFY": 1.480417802299969, "AERIUS": 1.2863812963334091, "AFINITOR": 0.2948194760167807, "AIMOVIG": 0.3651895074223194, "AMINOSALICYLIC": 0.5856239451425933, "ARAVA": 0.0323921588616792, "ARIPIPRAZOLE": 0.704016719411216, "ASPARAGINASE": 2.338732252311187, "ATAZANAVIR": 0.828105767299761, "AUBAGIO": 0.4867719245686926, "AZACITIDINE": 1.3502600432024805, "BEDAQUILINE": 1.7259130653484522, "BETAFERON": 0.7865546306919204, "BEXSERO": 1.8092693467726704, "BRINTELLIX": 0.574269581363775, "BRIVARACETAM": 8.376903608315061, "BRIVIACT": 20.591159463133124, "BUPIVACAINE": 2.411594132259743, "BUPRENORPHINE": 0.2163446623636285, "BUSULFAN": 1.5532237543989833, "CELLCEPT": 0.6027875895236083, "CETRORELIX": 56.12817963761371, "CHAMPIX": 1.3136209118990212, "CICLOSPORIN": 1.844403768519128, "CIMZIA": 0.1205073192722632, "CLOPIDOGREL": 0.1733305286543177, "COMIRNATY": 0.189683661946211, "CYMBALTA": 1.355595409766173, "CYTARABINE": 0.3652173744020691, "DARUNAVIR": 1.9193860249984804, "DELAMANID": 5.136273980007629, "DESLORATADINE": 2.5828653294725097, "DEXAMETHASONE": 1.6723530412452328, "DEXDOR": 9.923100689383936, "DOLUTEGRAVIR": 4.2633749946342725, "DULOXETINE": 1.5987635748721114, "EBIXA": 5.556787290429658, "EFAVIRENZ": 0.9511540375299394, "ELIQUIS": 0.0657862593820411, "ENTYVIO": 0.2487699849396958, "EPIDYOLEX": 9.221365612661124, "FAMPRIDINE": 11.65399367869762, "FAMPYRA": 4.795748504359378, "FENTANYL": 3.3438832568127, "FYCOMPA": 5.354562078945678, "GARDASIL": 3.695166276212011, "HUMALOG": 0.2375097547080739, "HYDROCORTISONE": 1.1427643724520409, "IBUPROFEN": 1.4422543605818134, "INFANRIX": 3.984424650539563, "JANUMET": 0.2033833570781349, "KAFTRIO": 0.6926048755149702, "KALETRA": 0.6931638538255116, "KEPPRA": 22.688763669656822, "KEYTRUDA": 0.0720893335390015, "LACOSAMIDE": 19.27628586420693, "LAMIVUDINE": 1.289308428215884, "LANTUS": 0.2217948859724267, "LATUDA": 0.4509370369446919, "LEVETIRACETAM": 17.398498038491827, "LEVOFLOXACIN": 1.2583637813087716, "LOXAPINE": 14.50084368750199, "LYRICA": 0.8803103543685378, "MEMANTINE": 3.6486530029508257, "MENVEO": 1.3576369632053404, "METHOTREXATE": 0.223441105941079, "MIDAZOLAM": 5.03831189883264, "MIMPARA": 1.211046645353974, "MMRVAXPRO": 0.6578192069993039, "MYCOPHENOLATE": 0.6085484166456134, "NIMENRIX": 2.9679871469706884, "NOT": 0.875637889052003, "NOXAFIL": 1.5500425740612227, "OLANZAPINE": 2.871823986264944, "OXYBUTYNIN": 4.248019653007331, "PANTOPRAZOLE": 0.7157173503331345, "PEGASYS": 0.6319312447197144, "PEGINTRON": 0.9491630953519702, "PLAVIX": 0.2122114147789995, "PREGABALIN": 1.030921789043132, "REBIF": 5.634915864517315, "RIBAVIRIN": 0.4959735195757772, "RISPERIDONE": 2.0941628084335417, "RITUXIMAB": 0.2710868437614609, "ROTATEQ": 0.499744071414748, "SHINGRIX": 0.1756549836405709, "SILDENAFIL": 1.827258987767144, "SOLIRIS": 0.6325786048580362, "SPIKEVAX": 0.1379316226260156, "STELARA": 0.1228122142634293, "STRIBILD": 0.1620217605434176, "SUBOXONE": 0.698684943658472, "SUFENTANIL": 1.4905845160780604, "SUTENT": 0.2265931524911625, "SYCREST": 6.330328912397482, "TACROLIMUS": 1.481580770942979, "TAMIFLU": 1.7009563832149974, "TOZINAMERAN": 0.4614476227348333, "TWINRIX": 1.8991113101693105, "VAXZEVRIA": 0.1319390293185179, "VFEND": 0.929173498364631, "VIAGRA": 0.53400038028396, "VIMPAT": 18.054479368923, "VOTRIENT": 0.2926074207610353, "XOLAIR": 0.1409432954788762, "XTANDI": 0.326613015065835, "ZYPREXA": 5.9862343331461885, "null": 2.6382294834454023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5064.json
index 697d4a0d0df..978a8eaa610 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5064.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5064.json
@@ -1 +1 @@
-{"null": 3.709147026364101}
\ No newline at end of file
+{"null": 0.9004185235913372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5065.json
index aae0c4c05d8..fac22e3c614 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5065.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5065.json
@@ -1 +1 @@
-{"null": 1.2897868525631466}
\ No newline at end of file
+{"COMIRNATY": 0.57417610885526, "JARDIANCE": 37.357908182237615, "null": 0.3509327131721231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5066.json
index 4314ffa2c64..f390ddc247d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5066.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5066.json
@@ -1 +1 @@
-{"null": 1.016791246989776}
\ No newline at end of file
+{"null": 6.267647605368683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5067.json
index ead79a1140b..112e289b5d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5067.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5067.json
@@ -1 +1 @@
-{"ZOSTAVAX": 18.358284377925024, "null": 3.880291025884471}
\ No newline at end of file
+{"null": 7.224155163960526}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5068.json
index b7d869979bf..2ec81f20b8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5068.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5068.json
@@ -1 +1 @@
-{"COSENTYX": 24.59267791278567, "JANUVIA": 32.371633368699}
\ No newline at end of file
+{"COMIRNATY": 0.6686134846890184, "JARDIANCE": 35.10184009340554, "null": 0.6875127170729862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5069.json
index 25c2711a80e..8c8360f6668 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5069.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5069.json
@@ -1 +1 @@
-{"ABILIFY": 11.54587732904396, "ARIPIPRAZOLE": 9.613997180296854, "BRINTELLIX": 9.3049790640852, "CHAMPIX": 7.747715824987102, "CYMBALTA": 5.413630572116798, "DULOXETINE": 3.266831703684594, "INTRONA": 6.337118613283159, "KAFTRIO": 1.964208653547035, "KEPPRA": 1.5720308698385077, "LATUDA": 36.81915325790826, "LEVETIRACETAM": 2.0401322781360087, "LURASIDONE": 26.33287787536992, "LYRICA": 1.1177826192014817, "OLANZAPINE": 10.67150246896983, "PANTOPRAZOLE": 1.3674135611623806, "PEGASYS": 1.6772593062429324, "PEGINTERFERON": 1.210793268492226, "PEGINTRON": 2.4160397795734907, "RIBAVIRIN": 2.823502289625839, "RISPERIDONE": 8.287095506684738, "SIFROL": 5.120873990572349, "SUBOXONE": 1.033478373235155, "SYCREST": 13.290526507603497, "TAMIFLU": 1.2244596719034446, "VARENICLINE": 16.873937286848534, "VFEND": 1.6682581432835737, "VIMPAT": 1.981299094672912, "VORICONAZOLE": 2.045216658957756, "XYREM": 3.17662604767393, "ZONISAMIDE": 14.720482474685856, "ZYPADHERA": 1.785027744810754, "ZYPREXA": 9.842347318232331, "null": 3.5628549587428404}
\ No newline at end of file
+{"COMIRNATY": 0.6252332030337514, "FORXIGA": 25.046667634019563, "JARDIANCE": 55.68933577067613, "SUTENT": 1.4606867161751391, "null": 1.6898409247418371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/507.json
index 2410bb49669..19e684bc3c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/507.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/507.json
@@ -1 +1 @@
-{"null": 1.2687455096402631}
\ No newline at end of file
+{"HEPSERA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5070.json
index 8ec153407f8..3625353e6c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5070.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5070.json
@@ -1 +1 @@
-{"null": 1.3092049495297184}
\ No newline at end of file
+{"COSENTYX": 10.837112412158406, "FORXIGA": 72.56172846573526, "JARDIANCE": 159.87264381542818, "null": 0.6948988787331483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5071.json
index fcf120dccfb..1c67366d453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5071.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5071.json
@@ -1 +1 @@
-{"CYTARABINE": 31.931146453856304, "RITUXIMAB": 29.88309948155111, "TORISEL": 140.79980342004131, "VENETOCLAX": 81.83991858205871}
\ No newline at end of file
+{"COMIRNATY": 1.2092517544568804, "JARDIANCE": 23.071954291026465, "null": 0.8971239776135098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5072.json
index 74caff8fa96..1afe14ba86d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5072.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5072.json
@@ -1 +1 @@
-{"ACALABRUTINIB": 4869.774588526102, "CAELYX": 129.70878503950638, "CARMUSTINE": 533.6099424136872, "CYTARABINE": 86.48253246507716, "IBRUTINIB": 455.5528273194338, "RITUXIMAB": 27.407653036525947}
\ No newline at end of file
+{"COMIRNATY": 0.8013583928855952, "FORXIGA": 31.209316829566628, "JARDIANCE": 34.512792909978344, "SPIKEVAX": 0.427094709559186, "SUTENT": 5.659528413941774, "null": 1.0788477815974706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5073.json
index 1c472909aaf..c1c8906f1ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5073.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5073.json
@@ -1 +1 @@
-{"null": 4.087854129026545}
\ No newline at end of file
+{"null": 0.809811682955197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5074.json
index 1b3ea0ec2c9..f4830b9f624 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5074.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5074.json
@@ -1 +1 @@
-{"null": 2.8181737538583063}
\ No newline at end of file
+{"AP": 7210.221152950711, "KONTRASTMITTEL": 10901.437672281838, "null": 1.751190995632305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5075.json
index b4ed7914b43..33a1f242f3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5075.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5075.json
@@ -1 +1 @@
-{"EVENITY": 87.59384467418964, "FORXIGA": 16.753327165652003, "MIRCERA": 233.95195806552343, "SIMPONI": 7.252200203772163}
\ No newline at end of file
+{"COMIRNATY": 0.2181762319831358, "FORXIGA": 39.2881386929236, "JARDIANCE": 74.2729635297026, "SUTENT": 5.401073181582177, "null": 1.1232413102872707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5076.json
index 0f3bcd3e807..2d9b4ec5c99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5076.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5076.json
@@ -1 +1 @@
-{"null": 4.680092339331298}
\ No newline at end of file
+{"BRILIQUE": 6.430989446292358, "CLOPIDOGREL": 3.3834186295780944, "COMIRNATY": 0.9734909098123752, "CYMBALTA": 0.901566138095182, "ELIQUIS": 4.261421513719472, "JARDIANCE": 2.2247190831009784, "SPIKEVAX": 0.5436960811532382, "SUTENT": 1.8442726600648776, "TOZINAMERAN": 0.632167770450384, "VAXZEVRIA": 0.4331151269307007, "null": 1.9773393850843417}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5077.json
index d322224ed15..a012658d1b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5077.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5077.json
@@ -1 +1 @@
-{"RITUXIMAB": 323.8160277764217}
\ No newline at end of file
+{"CICLOSPORIN": 1.414460050088215, "COMIRNATY": 2.6789805173979397, "ENBREL": 1.7276091782392025, "GARDASIL": 1.6269368483794542, "JARDIANCE": 2.22670782542874, "RINVOQ": 18.492770235745017, "SHINGRIX": 4.079620006066168, "SIMPONI": 2.1431170333354466, "SPIKEVAX": 1.264919060627498, "STELARA": 1.5238030689771642, "TOZINAMERAN": 1.9508086204693664, "VAXZEVRIA": 1.107122285268761, "XELJANZ": 1.2129524659539743, "ZOSTAVAX": 4.811290212582444, "null": 0.2154100808533468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5078.json
index b7eeebdca76..f56bc7d2002 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5078.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5078.json
@@ -1 +1 @@
-{"null": 3.75078864372996}
\ No newline at end of file
+{"COMIRNATY": 0.7802368621939515, "ZOSTAVAX": 18.866586307309586, "null": 0.2435226415735424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5079.json
index 7eef1aac7df..bcf91479265 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5079.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5079.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 32.88875257240407, "BUSULFAN": 17.4808144502965, "CICLOSPORIN": 5.838752940578392, "EXJADE": 13.520492208506973, "NPLATE": 37.25801268760016}
\ No newline at end of file
+{"COMIRNATY": 1.5918754155660295, "RINVOQ": 68.77505227064998, "SHINGRIX": 24.772332819476965, "ZOSTAVAX": 39.46033853163732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/508.json
index 14e6fcd2d2e..83c7138e812 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/508.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/508.json
@@ -1 +1 @@
-{"ELIQUIS": 9.288445782116971, "PRAXBIND": 1055.8045558201163}
\ No newline at end of file
+{"KUVAN": 2041.1466107797487, "MIDAZOLAM": 115.60085864622104, "null": 0.8409338086873693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5080.json
index b657670cbec..afcd8a44bb8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5080.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5080.json
@@ -1 +1 @@
-{"ABACAVIR": 1.2050350196378266, "AFINITOR": 2.679310747889804, "BYDUREON": 3.440559528329461, "CAPECITABINE": 1.78290008462325, "CICLOSPORIN": 2.51918533570359, "COSENTYX": 1.1708259727095394, "FASLODEX": 3.61378049065874, "FORSTEO": 2.3331873544068142, "HERCEPTIN": 2.654234136363378, "HUMIRA": 1.1008379603278216, "JAKAVI": 1.4113758152635356, "MEKINIST": 1.1821268432114025, "METHOTREXATE": 1.815033188414464, "OPTIMARK": 120.83878278883608, "PEGASYS": 2.1574938055007142, "REMICADE": 3.624027825682425, "ROACTEMRA": 1.1108014098618162, "SIMPONI": 2.8254636166684803, "STELARA": 1.9634297794614468, "SUTENT": 1.079956172068359, "TOZINAMERAN": 1.7425714733141346, "TRULICITY": 1.4132988241670592, "XELJANZ": 1.2253448084486922, "XOLAIR": 1.4965853856184594, "XTANDI": 1.651045562280472, "ZELBORAF": 21.7387670768274, "ZOSTAVAX": 1.5214334015077926}
\ No newline at end of file
+{"BRINTELLIX": 15.103086320626188, "COMIRNATY": 0.1278692677512951, "SPIKEVAX": 0.3048687859966147, "VIAGRA": 43.04346605830896, "null": 4.027928408583359}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5081.json
index f6b2a885aa0..68d117c780e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5081.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5081.json
@@ -1 +1 @@
-{"ENBREL": 21.894055788917104}
\ No newline at end of file
+{"FORXIGA": 133.53464918811915, "JARDIANCE": 622.5009415789317, "null": 0.0270627624043653}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5082.json
index d1a5e69ca93..4ef90480943 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5082.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5082.json
@@ -1 +1 @@
-{"CELECOXIB": 18.30157064051844, "COMIRNATY": 2.404794010561785, "GARDASIL": 19.37366384462523, "OMALIZUMAB": 7.42692119857508, "SPIKEVAX": 1.0925759409391629, "TOZINAMERAN": 2.990434072403617, "VAXZEVRIA": 1.1219446715493593, "XOLAIR": 8.266462843097395}
\ No newline at end of file
+{"FORXIGA": 284.6405467290686, "JARDIANCE": 136.09647261073528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5083.json
index 3ce76c14b5a..5ea83e43130 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5083.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5083.json
@@ -1 +1 @@
-{"DOCETAXEL": 9.743275516649092, "IBRANCE": 11.27277707633053, "JANUMET": 14.566003265736038, "JANUVIA": 12.177316021787306, "KEYTRUDA": 3.403633801052591, "XOLAIR": 4.165933766731786, "null": 2.040054694944704}
\ No newline at end of file
+{"COMIRNATY": 0.1424551946772617, "FORXIGA": 74.57950754489234, "JARDIANCE": 571.3668692659778, "SPIKEVAX": 0.1099996696851185, "null": 0.2164332825155219}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5084.json
index 94934478ebb..7a99bacde1c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5084.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5084.json
@@ -1 +1 @@
-{"ABILIFY": 5.240389297729403, "ATRIPLA": 1.074861692160828, "BUPRENORPHINE": 5.774222572980701, "GARDASIL": 1.59361747050843, "LEVETIRACETAM": 4.160746158167752, "SUTENT": 5.709438240412879, "TOZINAMERAN": 1.5558010847592876, "null": 1.080535232718128}
\ No newline at end of file
+{"FORXIGA": 234.59845650896727, "JARDIANCE": 318.4064627795978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5085.json
index 44c95701730..bbc37219cdd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5085.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5085.json
@@ -1 +1 @@
-{"COMIRNATY": 2.783125266355148, "IBRANCE": 4.795460322981487, "SPIKEVAX": 1.041097601621044, "STELARA": 2.783530067193339, "TOZINAMERAN": 4.257247956806352, "XELJANZ": 1.974141805694111}
\ No newline at end of file
+{"null": 1.5555904087896162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5086.json
index 546ad60da73..598e9be2c6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5086.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5086.json
@@ -1 +1 @@
-{"COMIRNATY": 11.228648755461542}
\ No newline at end of file
+{"GANCICLOVIR": 70.14313202692853, "null": 1.1319512542843513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5087.json
index 25a831a591b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5087.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5087.json
@@ -1 +1 @@
-{"OMALIZUMAB": 24.92111361971912}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5088.json
index 93d86db52e7..c5db9ef9b46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5088.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5088.json
@@ -1 +1 @@
-{"AIMOVIG": 153.45786364683454, "BOTULINUM": 85.07329063963378}
\ No newline at end of file
+{"INVEGA": 903.5286584417336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5089.json
index eb076c60f11..2946993f094 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5089.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5089.json
@@ -1 +1 @@
-{"ISENTRESS": 91.35380809590296, "null": 5.452461991893415}
\ No newline at end of file
+{"COMIRNATY": 2.0243300083787266, "FORXIGA": 8.985343778539445, "JARDIANCE": 20.408221633833275, "SPIKEVAX": 1.5995476372636224, "TOZINAMERAN": 0.5045238042984077, "VAXZEVRIA": 0.2755532995453022, "null": 0.8427669976055844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/509.json
index f41e1bcdce3..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/509.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/509.json
@@ -1 +1 @@
-{"KEPPRA": 23.470658096024444, "null": 3.884878719463113}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5090.json
index f936156ca66..fd8af30324e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5090.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5090.json
@@ -1 +1 @@
-{"ABACAVIR": 6.627569793842597, "ADALIMUMAB": 1.0478625903743743, "AIMOVIG": 1.2333286341639589, "ARAVA": 2.7943857226769566, "BRIVARACETAM": 55.54997841708654, "BRIVIACT": 46.264772324014366, "CIMZIA": 55.73641010039992, "DUPILUMAB": 155.54580913172757, "ESMYA": 27.08950782560163, "GARDASIL": 5.572073221524352, "INSULIN": 3.530598492227121, "KEPPRA": 14.029717863992246, "LACOSAMIDE": 8.317683615015683, "LEVETIRACETAM": 8.056050921382376, "MAVENCLAD": 35.14603627754939, "MMRVAXPRO": 11.285844510184155, "VIMPAT": 23.43509053558697}
\ No newline at end of file
+{"COMIRNATY": 0.3966444594897495, "null": 2.378485116964598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5091.json
index 709c743aa5d..50cadae82d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5091.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5091.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 2.9652835003547784, "BRIVARACETAM": 31.63918674749975, "BUPIVACAINE": 10.322884496813666, "CIMZIA": 13.108665570439214, "COVID19": 7.676688074161753, "DULOXETINE": 1.7470257447894906, "ENTYVIO": 2.114787289082662, "HUMALOG": 1.8324030320128128, "KEPPRA": 4.968293891651217, "KESIMPTA": 4.468809395352782, "RUCONEST": 16.68983578534393, "SOLIRIS": 2.504567731024204, "SPIKEVAX": 2.548655073136345, "SUBOXONE": 1.7163172932890234, "TOZINAMERAN": 2.0632600349081938, "VAXZEVRIA": 1.0787076183010889, "VIMPAT": 3.756021888934713}
\ No newline at end of file
+{"COMIRNATY": 0.2743483961294153, "FORXIGA": 24.883544478523486, "JARDIANCE": 23.55112053291146, "SHINGRIX": 5.185660131362184, "SUTENT": 7.368472604416787, "VAXZEVRIA": 0.1321607285055279, "null": 0.9978588114555428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5092.json
index 52f95adc8ed..c6405eb8a93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5092.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5092.json
@@ -1 +1 @@
-{"BRIDION": 11.927981808903398, "BUPIVACAINE": 113.3381710601659, "FENTANYL": 34.60321775898639, "SUFENTANIL": 66.73311128693486, "null": 7.157070214281162}
\ No newline at end of file
+{"COMIRNATY": 0.364556218281038, "FORXIGA": 41.974229710828745, "JARDIANCE": 36.646453056991625, "SPIKEVAX": 0.3252335443977909, "null": 1.3375035083773053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5093.json
index 9b3081e7c22..ad302c67113 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5093.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5093.json
@@ -1 +1 @@
-{"ABACAVIR": 3.212953764124815, "ABASAGLAR": 1.0144146924856878, "ABATACEPT": 4.02870271799851, "ABILIFY": 3.874135695304656, "ACTRAPID": 1.76778488748224, "ADALIMUMAB": 6.0895209360909455, "AERIUS": 1.7277940605224908, "AIMOVIG": 1.4475051583667409, "ALECTINIB": 9.569216513522722, "ALISKIREN": 1.4065084445306888, "ANTIBIOTICS": 3.256675899068878, "APREMILAST": 2.6306432381254594, "ARAVA": 10.60486212078613, "ARIPIPRAZOLE": 2.192177892259071, "ATAZANAVIR": 4.277587027962828, "ATOSIBAN": 68.47129950844143, "AZATHIOPRINE": 5.601539424357867, "BARACLUDE": 3.500331343764132, "BENZODIAZEPINE": 1.2201368828039705, "BETAFERON": 1.760089395652519, "BIKTARVY": 3.3975395285741725, "BOTULINUM": 1.0436607503923028, "BRIVARACETAM": 13.402411002774071, "BRIVIACT": 6.396402171704837, "BUPIVACAINE": 7.964337031256709, "BUPRENORPHINE": 6.134404078914449, "BUVIDAL": 13.16100771631348, "CHLORHEXIDINE": 1.8188257328559736, "CIMZIA": 8.501416567092992, "CINACALCET": 6.86188301810864, "COMBIVIR": 2.6424769547444047, "CORTICOSTEROIDS": 4.2380256575224085, "COSENTYX": 1.6040669534341665, "CYTARABINE": 1.728710139224462, "DARBEPOETIN": 1.9701491316647912, "DARUNAVIR": 8.53356983614865, "DESLORATADINE": 1.0799978711372338, "DEXAMETHASONE": 2.3210288984604035, "DEXMEDETOMIDINE": 4.39142746434673, "DULOXETINE": 1.553276001451342, "DUPILUMAB": 6.654305319862672, "EFAVIRENZ": 8.483672841340296, "ELLAONE": 1.4800867702239071, "EMTRICITABINE": 8.152203166310473, "EMTRIVA": 4.4599457388284085, "ENOXAPARIN": 4.166509741527456, "EPCLUSA": 1.8541648711911425, "EPIVIR": 1.2611578600931517, "EPOETIN": 4.690423265148625, "ERELZI": 2.012687356705128, "ESMYA": 2.3331818032683858, "ESOMEPRAZOLE": 1.441191361350293, "EVIPLERA": 19.13131250383814, "EVRA": 2.973803311670892, "FENTANYL": 3.5402526692869505, "FIASP": 3.7175474671029263, "FILGRASTIM": 1.0588139326071753, "GENVOYA": 5.323618502408802, "GLIVEC": 1.048970879521813, "HUMALOG": 1.6761047755119047, "HUMAN": 3.2685919883204533, "HYDROCORTISONE": 3.014403411871577, "ILOPROST": 17.1657129290093, "INFLIXIMAB": 1.058381144253814, "INHIXA": 5.327997557508038, "INSULATARD": 4.375293189711445, "INSULIN": 2.608956472803196, "INTELENCE": 4.846197871679369, "IRON": 4.415670321833552, "ISENTRESS": 11.888837358995266, "KAFTRIO": 1.192957589782469, "KALETRA": 1.3950402345412105, "KEPPRA": 8.66098384054666, "KESIMPTA": 1.5252086877221238, "KIVEXA": 1.536363880519723, "KUVAN": 14.039416233340251, "LACOSAMIDE": 5.589082799254214, "LAMIVUDINE": 2.054066480569113, "LATUDA": 1.390175500943266, "LEVEMIR": 6.406750246669916, "LEVETIRACETAM": 4.624810248682817, "LOPINAVIR": 4.345046649392438, "MIDAZOLAM": 1.5199589039112182, "MISOPROSTOL": 9.446188138221132, "MIXTARD": 3.0016215913852964, "MYCOPHENOLATE": 1.0134936708483564, "NEVIRAPINE": 6.852834294827379, "NILOTINIB": 1.1968181072634307, "NORVIR": 6.9877197980120105, "NOVORAPID": 2.026240384028059, "NPLATE": 1.18860758466601, "OLANZAPINE": 1.2178599386162146, "OPIOIDS": 3.468688777077636, "OSELTAMIVIR": 11.32997835754546, "PLEGRIDY": 2.785077754649936, "PROTAPHANE": 12.127560380236863, "QUTENZA": 1.2769095309674308, "REMDESIVIR": 2.570930384658349, "REMICADE": 1.798077652070412, "REYATAZ": 5.0191106146855775, "RINVOQ": 1.430982737622841, "RITUXIMAB": 1.3282928846393058, "RUCONEST": 8.816119739164813, "SAXENDA": 1.7364270178775552, "SILDENAFIL": 3.500998077933269, "SKYRIZI": 2.287321105344685, "SPINRAZA": 1.3772748580081209, "SPIRONOLACTONE": 1.4011877308361709, "SUBOXONE": 8.588988252791335, "SUFENTANIL": 3.148377370358524, "TACROLIMUS": 1.190897055200922, "TAMIFLU": 1.5306062627137214, "TENOFOVIR": 6.16179687642922, "THYROID": 96.34696146561234, "TOCILIZUMAB": 1.506048058537083, "TRACTOCILE": 6.326833517989214, "TRESIBA": 2.10005472095654, "VEKLURY": 4.3910939728096015, "VEMLIDY": 2.955896832124799, "VIGABATRIN": 3.5638714753386647, "VIMPAT": 6.051934033251827, "VIREAD": 1.6931467942198877, "XOLAIR": 3.8061345723664624}
\ No newline at end of file
+{"COMIRNATY": 0.3969299670919849, "DULAGLUTIDE": 180.75724255187797, "FORXIGA": 61.75579153760319, "JARDIANCE": 152.6328820168078, "null": 0.3013204585355152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5094.json
index 0f5675b641f..8b12f11b34b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5094.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5094.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.971321771847468, "APIDRA": 2.697791923505208, "AZATHIOPRINE": 19.048869196746463, "COMBIVIR": 27.75796375603813, "COMIRNATY": 1.164771531009548, "COSENTYX": 5.557354257826239, "CRIXIVAN": 53.1598718254657, "EFAVIRENZ": 10.250307255066904, "FENTANYL": 8.419994895328559, "IBUPROFEN": 3.572631583992928, "ISENTRESS": 8.722990414245237, "MAVENCLAD": 18.5411422160925, "METHOTREXATE": 5.702010758519705, "RITUXIMAB": 2.9237512487509574, "TOZINAMERAN": 1.5939710018429971, "XOLAIR": 1.51890582295109, "null": 1.481015692912102}
\ No newline at end of file
+{"COMIRNATY": 0.4417166137039018, "JARDIANCE": 12.778868182044157, "SPIKEVAX": 0.4091553277382923, "TOZINAMERAN": 0.7927172306444383, "VAXZEVRIA": 0.2269634097292256, "null": 0.9267834476877052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5095.json
index 2a3e30125f5..f268e93183e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5095.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5095.json
@@ -1 +1 @@
-{"AIMOVIG": 91.6856170724836}
\ No newline at end of file
+{"APTIVUS": 3472.013490665753, "null": 1.5814979032827292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5096.json
index 50d1e0cbe87..766388df6c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5096.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5096.json
@@ -1 +1 @@
-{"FENTANYL": 40.533543464208, "null": 2.102911391962367}
\ No newline at end of file
+{"GARDASIL": 35.76787976752307, "null": 0.7935073517165068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5097.json
index 435f5520021..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5097.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5097.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 11.68731339176432, "CICLOSPORIN": 3.489602736136421, "IBUPROFEN": 10.572978677337328, "JAKAVI": 17.361117034449848, "SUTENT": 2.1676870297869315}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5098.json
index a2bbef50ecd..8908d041f86 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5098.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5098.json
@@ -1 +1 @@
-{"KYMRIAH": 63.47993213053206}
\ No newline at end of file
+{"null": 0.7199158905365257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5099.json
index 9f2e52bc601..8e6fdff5c88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5099.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5099.json
@@ -1 +1 @@
-{"ABATACEPT": 12.679799079149811, "ADALIMUMAB": 6.810342603969291, "ALEMTUZUMAB": 44.057680901303655, "ARIPIPRAZOLE": 13.97068263833318, "CLOPIDOGREL": 6.658986189078273, "LEMTRADA": 27.158257191841624, "XELJANZ": 2.676231691943449}
\ No newline at end of file
+{"LIXIANA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/51.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/51.json
index f2e60ee5eaf..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/51.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/51.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7112830867708326}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/510.json
index c1d9b4dab3c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/510.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/510.json
@@ -1 +1 @@
-{"KEPPRA": 10.518731967446165, "LACOSAMIDE": 59.6952048166675, "LEVETIRACETAM": 30.799991497847827, "null": 4.267365141095341}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5100.json
index 62325bb387a..f8b2e126845 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5100.json
@@ -1 +1 @@
-{"ADENURIC": 64.78516098067134, "ARAVA": 6.95476286059655, "ARIPIPRAZOLE": 8.466790627019492, "IBRANCE": 15.138469951290771, "KEYTRUDA": 3.238949866378964}
\ No newline at end of file
+{"FORXIGA": 75.5057731662356, "JARDIANCE": 330.8622086352936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5101.json
index ce77dba335a..7aa318812a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5101.json
@@ -1 +1 @@
-{"ABATACEPT": 15.183263770956415, "ADALIMUMAB": 5.876550718248341, "ARIPIPRAZOLE": 8.81982534180345, "ENBREL": 4.536834626904256, "JAKAVI": 14.910970826041302, "LEMTRADA": 16.24632739922808, "NUCALA": 6.057295339447124}
\ No newline at end of file
+{"null": 0.9505518610027304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5102.json
index 47e49341c98..0eeae09f8fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5102.json
@@ -1 +1 @@
-{"ADENURIC": 47.9568886855016, "BEVACIZUMAB": 12.530608336139084, "EXJADE": 9.63950830565918, "IBRANCE": 19.306710242500284, "JAKAVI": 13.54089698954817, "LEMTRADA": 11.551232672526217, "PEGASYS": 1.8421951734116415, "PEGINTRON": 5.502575046946735, "SOLIRIS": 11.107163247770677, "SUTENT": 2.258146127077712}
\ No newline at end of file
+{"EFAVIRENZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5103.json
index 8d2773b1ecc..f13b1a17ad2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5103.json
@@ -1 +1 @@
-{"ABATACEPT": 33.45090619095597, "ADALIMUMAB": 8.927738169431281, "CICLOSPORIN": 6.875277705809002}
\ No newline at end of file
+{"ABACAVIR": 4.022235736866002, "ATRIPLA": 2.8460607298242477, "BIKTARVY": 115.6037006985006, "DACLATASVIR": 605.38686445476, "DAKLINZA": 76.88646183118409, "DARUNAVIR": 38.88981273607956, "EMTRICITABINE": 69.99170557169604, "EMTRIVA": 232.04572794552456, "EPCLUSA": 230.96761373882345, "GENVOYA": 109.00034409569749, "HARVONI": 209.12966486986124, "HEPSERA": 38.522496795404365, "ISENTRESS": 19.14264409014666, "RIBAVIRIN": 69.62172040059913, "SOFOSBUVIR": 117.6370637123594, "SOVALDI": 15.422815593871432, "STRIBILD": 10.881243385437315, "TRUVADA": 8.898345177071272, "VEKLURY": 29.351147639113016, "VIREAD": 18.85327797861016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5104.json
index 1405b65079a..bc42b277645 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5104.json
@@ -1 +1 @@
-{"ENTRESTO": 43.03522717998387}
\ No newline at end of file
+{"CYTARABINE": 181.16345793633465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5105.json
index f04db6517e6..9977cee8e6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5105.json
@@ -1 +1 @@
-{"MMRVAXPRO": 43.75512412166614, "PREVENAR": 23.523625146675386, "null": 6.399006905116629}
\ No newline at end of file
+{"null": 0.800415278061176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5106.json
index 99c72545099..504f5c25b63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5106.json
@@ -1 +1 @@
-{"MMRVAXPRO": 138.13164024857514, "null": 2.790604720356131}
\ No newline at end of file
+{"BLINATUMOMAB": 4947.162511445805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5107.json
index a37fe897fd5..ac74bbc6689 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5107.json
@@ -1 +1 @@
-{"MMRVAXPRO": 137.43701108319576, "null": 5.085845879805}
\ No newline at end of file
+{"ABILIFY": 14.368150281486573, "BIKTARVY": 5.749868437892848, "BUVIDAL": 63.6846969407586, "CIMZIA": 5.49513050315054, "COMBIVIR": 17.74221502584702, "CYMBALTA": 0.8675518937279735, "DOLUTEGRAVIR": 33.81449259053695, "DULOXETINE": 7.680691723769849, "HUMALOG": 1.05862145809775, "KAFTRIO": 10.348107517383331, "KEPPRA": 1.9698543384799316, "LATUDA": 5.311467690673049, "NORVIR": 28.894697793690543, "OLANZAPINE": 9.59414354391342, "STELARA": 1.6401143808966063, "SUBOXONE": 6.122302551536591, "VAXZEVRIA": 0.0534592755903398, "ZYPREXA": 10.068843221680137, "null": 1.5310822649029046}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5108.json
index 38b84f7d929..31f2ae7ea3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5108.json
@@ -1 +1 @@
-{"null": 1.0259410925767232}
\ No newline at end of file
+{"ABILIFY": 24.283716257423404, "AERIUS": 90.30663702201907, "CICLOSPORIN": 3.697325478305274, "CIMZIA": 2.654389356451843, "COMBIVIR": 24.861693204686684, "DUPILUMAB": 532.0404063831385, "GARDASIL": 2.809742312328228, "HUMALOG": 3.91957520817228, "INSULIN": 13.98205614390136, "LEVEMIR": 10.428691246535964, "SUBOXONE": 16.514168120873606, "null": 1.088065987902754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5109.json
index 9c7aad15f80..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5109.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2401067631206522, "GARDASIL": 1.9776454014107756, "OMALIZUMAB": 4.674798296271496, "SPIKEVAX": 9.034999274725912}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/511.json
index e49babebdc1..5e8a6de83c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/511.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/511.json
@@ -1 +1 @@
-{"KEPPRA": 15.615018967311784, "LACOSAMIDE": 29.92555352076628, "LEVETIRACETAM": 33.849691263280874, "null": 4.168703922756898}
\ No newline at end of file
+{"HEPSERA": 731.2622665216284, "null": 0.921897804784552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5110.json
index 106c404c5a9..a96a50dd56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5110.json
@@ -1 +1 @@
-{"BIKTARVY": 5.804577235091415, "BRIDION": 22.86680617419127, "CICLOSPORIN": 10.72605917659054, "CUBICIN": 9.780774841754138, "FENTANYL": 3.632316812850788, "KALETRA": 15.43189770366376, "KEPPRA": 1.9889078668003903, "OPSUMIT": 2.350065859815498, "TRACLEER": 16.09085387542, "VEKLURY": 39.69780482614727, "ZYPREXA": 1.5843542372449295, "null": 1.679195729477925}
\ No newline at end of file
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5111.json
index 9b92426b09a..37367bc2b3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5111.json
@@ -1 +1 @@
-{"BUDESONIDE": 86.36942001783544, "FENTANYL": 25.83484401047674, "MIDAZOLAM": 78.83418505750022, "SPINRAZA": 111.4787948553636}
\ No newline at end of file
+{"MMRVAXPRO": 53.6910382152705, "null": 1.6237216251425384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5112.json
index 25f0a4d43fe..11ad212fbe0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5112.json
@@ -1 +1 @@
-{"null": 4.469397015128806}
\ No newline at end of file
+{"COMIRNATY": 2.282114266233351, "IPILIMUMAB": 9.109378620817504, "OMALIZUMAB": 3.940223867404386, "ROACTEMRA": 15.951950522449064, "SHINGRIX": 2.978847776514664, "SPIKEVAX": 1.0129146366520083, "TELMISARTAN": 34.0285107602632, "TOZINAMERAN": 1.3597832675800328, "VAXZEVRIA": 1.3342900722956188, "ZOSTAVAX": 6.615790371612311, "null": 0.3215593136985311}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5113.json
index 11b989d4ace..c1bbb4b698c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5113.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 55.65212136844276, "SUBOXONE": 62.304379222774536, "null": 1.131952637324735}
\ No newline at end of file
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5114.json
index c3d9becbc4e..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5114.json
@@ -1 +1 @@
-{"null": 1.1464456165419163}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5115.json
index bbc7b3e6b1b..eddf3984908 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5115.json
@@ -1 +1 @@
-{"COMBIVIR": 41.224156739232924, "null": 4.022890261345194}
\ No newline at end of file
+{"null": 0.4265354194532689}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5116.json
index ad012f4c159..bf5ddf7c6d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5116.json
@@ -1 +1 @@
-{"SUBOXONE": 33.18421055559569, "null": 1.0985433920604462}
\ No newline at end of file
+{"COMIRNATY": 0.3968357729843311, "KAFTRIO": 523.3148854066509, "null": 0.4913385892519531}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5117.json
index 905040779a7..94a98b22790 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5117.json
@@ -1 +1 @@
-{"CUBICIN": 237.4138931489093}
\ No newline at end of file
+{"COMIRNATY": 0.2553877881173277, "DULOXETINE": 48.83039354485118, "LEFLUNOMIDE": 172.0566540200923, "SIMPONI": 14.519827635965832, "VAXZEVRIA": 0.3734227225557804, "null": 0.5708977850179239}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5118.json
index 0282145cbeb..d7003eb8068 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5118.json
@@ -1 +1 @@
-{"ADCIRCA": 206.16236740389}
\ No newline at end of file
+{"null": 1.1654417738127898}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5119.json
index 421a776d781..3a507711da2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5119.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 53.67010567280488, "null": 1.660551333735505}
\ No newline at end of file
+{"AFINITOR": 0.5601674323484627, "AIMOVIG": 1.1164819343762094, "APIXABAN": 0.451890700588497, "ARAVA": 0.2560000180998396, "AVASTIN": 0.9343174121038872, "BEVACIZUMAB": 1.501579209600382, "BRILIQUE": 12.123229652373457, "BRINTELLIX": 1.4074091712468009, "BUPRENORPHINE": 0.7122383827571395, "BYETTA": 0.5675123413493395, "CABOMETYX": 1.3481087885138532, "CHAMPIX": 1.7559644966531731, "CICLOSPORIN": 1.468063067116888, "CIMZIA": 0.1862611596194995, "CLOPIDOGREL": 8.336520297498446, "COAPROVEL": 1.8682482309613844, "COMIRNATY": 0.4192642845361184, "COSENTYX": 0.3199050475716001, "DEXAMETHASONE": 0.4475992125418314, "EFIENT": 7.418668739802642, "ELIQUIS": 8.81294995352432, "ELTROMBOPAG": 23.57195985885075, "ENBREL": 0.4100168709082507, "ENOXAPARIN": 3.9811616580341145, "EXJADE": 0.4883156422069629, "FORSTEO": 0.366806804800819, "GARDASIL": 0.6203891724461664, "HEMLIBRA": 13.547923342503749, "IBRANCE": 1.1141811309458414, "INCIVO": 2.909971761452355, "INTEGRILIN": 9.913264867442908, "INTRONA": 3.262624305993968, "KEPPRA": 0.6816285526982722, "LEMTRADA": 3.652575526297622, "LENVIMA": 1.653810230931746, "LEVETIRACETAM": 0.5147677866613001, "LIXIANA": 16.23723168019448, "NEXAVAR": 3.17010531532471, "NPLATE": 5.727288356321504, "PEGASYS": 3.71265382402777, "PEGINTERFERON": 1.2417372661632369, "PEGINTRON": 3.036156598972957, "PLAVIX": 8.886655857877885, "PRADAXA": 8.706464692511164, "RIBAVIRIN": 1.017392538857917, "ROACTEMRA": 0.8665748923975926, "SIMPONI": 0.4879854138082732, "SOLIRIS": 1.0284820587705945, "SPIKEVAX": 0.2595971266411895, "STIVARGA": 2.2531532524976754, "SUTENT": 4.02706349040044, "TAMIFLU": 0.6886945765145139, "TASIGNA": 1.0282687800462391, "TEMODAL": 2.848373774378412, "TICAGRELOR": 14.890783877736542, "TOZINAMERAN": 0.4916165261143909, "VAXZEVRIA": 0.7425142213405459, "VOTRIENT": 0.6923405623823672, "XARELTO": 13.3193976871396, "XTANDI": 0.4264392425969532, "null": 1.2240995780113797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/512.json
index 99330bf4b41..c214875dbb0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/512.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/512.json
@@ -1 +1 @@
-{"KEPPRA": 10.621659216411144, "LEVETIRACETAM": 21.300144797851804, "null": 6.537895630009107}
\ No newline at end of file
+{"null": 2.5069703921797624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5120.json
index b5c1f2b5459..bd7001aaa4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5120.json
@@ -1 +1 @@
-{"null": 1.5160708865908477}
\ No newline at end of file
+{"COMIRNATY": 0.7048447366327104, "TOZINAMERAN": 2.16759500337661, "VAXZEVRIA": 0.9885219343426226, "null": 1.1835944550764812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5121.json
index 87a6290f8db..9241be38556 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5121.json
@@ -1 +1 @@
-{"STIVARGA": 24.471039095289207}
\ No newline at end of file
+{"null": 1.4285586325439394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5122.json
index 97f0d8e0c0d..7a2b1c886b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5122.json
@@ -1 +1 @@
-{"CICLOSPORIN": 10.645728315859296, "null": 1.2309577084831436}
\ No newline at end of file
+{"COMIRNATY": 0.3598093299538754, "null": 1.824953776358388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5123.json
index 0b194ecb1d0..ac674f2ffc4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5123.json
@@ -1 +1 @@
-{"OPSUMIT": 75.4139689515332, "TRACLEER": 47.81268563204908, "null": 1.1813218191891224}
\ No newline at end of file
+{"COMIRNATY": 0.7485416070025688, "SPIKEVAX": 0.4768045093118609, "SUTENT": 6.065385247770869, "VAXZEVRIA": 0.2773630811777397, "null": 2.332202471150379}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5124.json
index 425ebc7ab3c..39e097edc0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5124.json
@@ -1 +1 @@
-{"BUPIVACAINE": 290.63123174664247, "FENTANYL": 28.25812347954277, "null": 1.3510682248624}
\ No newline at end of file
+{"AIMOVIG": 2.5220558977492886, "BRIVARACETAM": 47.87628306976799, "CICLOSPORIN": 1.7935718838560235, "COMIRNATY": 0.1498719167651758, "ELIQUIS": 1.5424859504935575, "FORSTEO": 2.81331691899648, "HYDROCORTISONE": 21.50384544829572, "IBRANCE": 2.0558446648102597, "KEPPRA": 3.961454023216485, "LEFLUNOMIDE": 31.36864171977029, "PEGASYS": 1.3759875851467047, "SUBOXONE": 2.8140812955514574, "SUTENT": 6.232221360570755, "TOZINAMERAN": 0.2795165469570268, "VAXZEVRIA": 0.1813564809294786, "null": 1.439428204853727}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5125.json
index b198b06fe85..5cca95e1e1c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5125.json
@@ -1 +1 @@
-{"ARAVA": 2.991779229381196, "HUMIRA": 19.37971712124573, "SIMPONI": 12.894906770410708}
\ No newline at end of file
+{"null": 2.3409756031485403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5126.json
index 93beb9ff4da..fa6417dd96e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5126.json
@@ -1 +1 @@
-{"null": 1.6222395180044056}
\ No newline at end of file
+{"COMIRNATY": 0.1841220349345345, "null": 2.1523696507168224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5127.json
index e007dce6536..acfe7238125 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5127.json
@@ -1 +1 @@
-{"AVONEX": 612.9718071700232, "FORSTEO": 27.189727481559476}
\ No newline at end of file
+{"null": 2.386097647336676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5128.json
index 5497c055589..325f3a6e18b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5128.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 512.8726411463114}
\ No newline at end of file
+{"CELLCEPT": 5.931761485528994, "CICLOSPORIN": 54.98124570209416, "EXFORGE": 20.66609785754913, "KEPPRA": 4.361989239904805, "LEVETIRACETAM": 8.952639175588828, "MYCOPHENOLATE": 11.531704646710814, "null": 2.81930901055226}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5129.json
index f16ee10de1d..90ede2837eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5129.json
@@ -1 +1 @@
-{"FAMPRIDINE": 4436.643070289055}
\ No newline at end of file
+{"null": 1.0552223260526887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/513.json
index df6004a4fd1..09bdfb1b78a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/513.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/513.json
@@ -1 +1 @@
-{"BRIVARACETAM": 53.10643467084547, "FYCOMPA": 37.00809436042189, "KEPPRA": 11.998846866472894, "LACOSAMIDE": 20.78181766814305, "LEVETIRACETAM": 12.941280590671036, "VIMPAT": 12.554149828038058, "null": 5.135149256780477}
\ No newline at end of file
+{"ASPARAGINASE": 4.166168267425813, "CLOPIDOGREL": 0.7937481933751357, "COMBIVIR": 3.869856930423088, "CORTICOSTEROIDS": 66.1559910842339, "EXJADE": 4.95919371310263, "FENTANYL": 1.2910719911535578, "HARVONI": 4.73377396540167, "IBUPROFEN": 1.7862297721018587, "KEPPRA": 3.57118576963517, "LANTUS": 0.6258192278324064, "LENVIMA": 39.94253449630861, "LEVETIRACETAM": 7.289186730475309, "NEXAVAR": 12.103147509851594, "OLANZAPINE": 2.901037255083975, "OPSUMIT": 1.6296910939533875, "PEGASYS": 8.490191464134423, "PEGINTRON": 3.3838107428023614, "SODIUM": 85.14768935177429, "SOVALDI": 7.394131877404162, "STIVARGA": 9.495013922609548, "SUTENT": 0.4657434324196066, "TRACLEER": 2.150567695161058, "ZYPREXA": 1.2177058349041028, "null": 2.356053223847318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5130.json
index 0c1b00c1eba..5b84b8e54bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5130.json
@@ -1 +1 @@
-{"CYMBALTA": 18.672592179462804, "FAMPRIDINE": 2704.271097350109, "PANTOPRAZOLE": 120.44037892017955}
\ No newline at end of file
+{"COMIRNATY": 1.0451808356231165, "VAXZEVRIA": 0.4409501103731193, "null": 2.5552896092205404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5131.json
index 026055a05e0..a026770cc59 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5131.json
@@ -1 +1 @@
-{"KEPPRA": 56.36560644688014, "PANTOPRAZOLE": 147.20905208316307}
\ No newline at end of file
+{"ADALIMUMAB": 4.395535279019419, "AFINITOR": 1.64576494586669, "AIMOVIG": 1.426991884016456, "BUDESONIDE": 0.9266934158280904, "CAPECITABINE": 2.7097286272148766, "CHAMPIX": 3.854249837068328, "CICLOSPORIN": 0.580252392205958, "COMIRNATY": 0.6055865858047087, "ELIQUIS": 0.4702720141825287, "FORSTEO": 1.661687952544587, "IBRANCE": 2.4404917280363727, "INLYTA": 2.2301662877538724, "KEPPRA": 0.7155394074932895, "NEXAVAR": 1.7934441479595036, "PEGASYS": 2.3317856275493303, "RELVAR": 5.892239857535707, "RINVOQ": 6.64556612979422, "SPIKEVAX": 0.6390948938992836, "SUTENT": 10.8486246776352, "TOVIAZ": 3.49278620452905, "TOZINAMERAN": 1.5480226783902438, "VAXZEVRIA": 1.1550286779083228, "XELJANZ": 1.0518224520064043, "null": 0.8867802900489397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5132.json
index 098d7c1b187..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5132.json
@@ -1 +1 @@
-{"KEPPRA": 140.10334883477805}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5133.json
index b60e5da0218..8e18bb4332b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5133.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 157.729003413971}
\ No newline at end of file
+{"COMIRNATY": 0.8175416320602392, "null": 1.7820739510549428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5134.json
index 9c5c3890670..c206c9d4a79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5134.json
@@ -1 +1 @@
-{"AVONEX": 1110.911552596269, "FAMPRIDINE": 944.4046531340248}
\ No newline at end of file
+{"ATRIPLA": 1.6133362768730306, "BUPRENORPHINE": 9.224254111903605, "COMIRNATY": 0.2092460865767811, "KEPPRA": 4.55913770045477, "PEGASYS": 1.6962904305852158, "SUTENT": 3.608593798958621, "null": 1.3840468649756137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5135.json
index 0a8d8210dac..d9a71cb3251 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5135.json
@@ -1 +1 @@
-{"RENVELA": 51920.25683250734}
\ No newline at end of file
+{"AFINITOR": 2.7056496873107467, "CHAMPIX": 1.8155690092949568, "CICLOSPORIN": 2.493216446457698, "CIMZIA": 0.8227455186894418, "COMIRNATY": 0.6779438042006566, "ELIQUIS": 0.6753136075789934, "EXFORGE": 5.515886743692176, "KEPPRA": 3.186319986787728, "PEGASYS": 1.1453537150129305, "SPIKEVAX": 0.4367260486571947, "SUTENT": 6.428086433308337, "TOZINAMERAN": 1.075246457814775, "VAXZEVRIA": 0.6534359526097039, "XELJANZ": 1.245075152718613, "null": 1.4135145175884785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5136.json
index 3fd0234a287..35ae9020239 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5136.json
@@ -1 +1 @@
-{"ATRIPLA": 14.769176305851964}
\ No newline at end of file
+{"COMIRNATY": 0.2370933834068665, "null": 1.0036032441389895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5137.json
index 7cca76cd765..27d63254902 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5137.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0870936689223134}
\ No newline at end of file
+{"CICLOSPORIN": 175.34681513972532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5138.json
index 92a20725da3..9a47076f216 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5138.json
@@ -1 +1 @@
-{"BUPIVACAINE": 292.7905486857145, "SUBOXONE": 60.93715936813632}
\ No newline at end of file
+{"AFINITOR": 2.7368213733069697, "AIMOVIG": 1.097960693502301, "ARAVA": 0.2483544084850876, "AUBAGIO": 1.310907351140809, "BONVIVA": 12.047995164160998, "CHAMPIX": 2.3578315615691428, "CICLOSPORIN": 0.780396328167767, "CIMZIA": 0.5487796856750149, "COMIRNATY": 0.6688710527552539, "COSENTYX": 1.8821177176399693, "EFAVIRENZ": 8.1527815367198, "ELIQUIS": 0.6137489379891469, "FORSTEO": 1.0807197562351838, "GARDASIL": 0.5808979391056253, "IBRANCE": 1.817134211425432, "INCIVO": 3.012246640751563, "JANUVIA": 2.160676047524135, "JARDIANCE": 0.795044813060103, "KEPPRA": 1.3205818297310878, "KEYTRUDA": 2.084454227897091, "LENVIMA": 4.872605574255534, "METHOTREXATE": 1.3808519236974497, "PEGASYS": 1.7055534468914422, "PEGINTRON": 1.3832536189425058, "ROACTEMRA": 3.1107883865946317, "SIMPONI": 2.523489823763614, "SPIKEVAX": 0.5475931089356249, "STELARA": 2.3456634855385747, "SUTENT": 2.1932608461011385, "TOZINAMERAN": 0.1542547886039511, "VAXZEVRIA": 0.3784877119833987, "XELJANZ": 1.957551038894738, "null": 1.0949716629382145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5139.json
index 7b9a914e041..b89024eeaed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5139.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"null": 0.6262677824534585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/514.json
index edf397140fb..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/514.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/514.json
@@ -1 +1 @@
-{"DULOXETINE": 167.80463970365986, "null": 3.636371078044172}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5140.json
index f01d6088860..a69846ea5de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5140.json
@@ -1 +1 @@
-{"ABATACEPT": 2.57033741951046, "ABILIFY": 1.144259531972193, "ACTOS": 4.340907312744745, "ACTRAPID": 4.693481095594937, "ADALIMUMAB": 2.133456754265262, "AERIUS": 1.8722905911844951, "ALISKIREN": 6.195840590800977, "ANAKINRA": 1.4046333313208537, "APIDRA": 7.345847296120676, "APREPITANT": 1.6408268337654228, "APROVEL": 3.61114791705552, "BONVIVA": 1.483214904902035, "BORTEZOMIB": 1.111875526794642, "BUPIVACAINE": 1.762416780179176, "CHLORHEXIDINE": 3.6426584920878873, "CIMZIA": 1.878332271774714, "CLOPIDOGREL": 2.0525608085852287, "COAPROVEL": 4.1382477360439855, "DULOXETINE": 2.1409719353601835, "EBIXA": 2.4363366817870347, "EMPAGLIFLOZIN": 3.2566071668004475, "ERELZI": 4.28559222115168, "EVRA": 5.027118328797085, "EXFORGE": 1.0917647871953942, "FENTANYL": 2.242022671841251, "GARDASIL": 1.4613459269416929, "GLIBENCLAMIDE": 5.299132169168445, "HUMALOG": 3.285766161547184, "HYDROCORTISONE": 5.173922249640948, "IBUPROFEN": 4.136007331880804, "INSULIN": 2.3451829841043774, "IRBESARTAN": 1.2324706505789889, "JANUVIA": 1.0191709289425763, "KEPPRA": 1.720011710869357, "LACOSAMIDE": 4.813553254079814, "LANTUS": 4.563657120977821, "LEVEMIR": 1.2143202473961778, "LURASIDONE": 14.313870110906905, "MICARDIS": 1.5234765297342503, "MIDAZOLAM": 2.2694086075189874, "NEVANAC": 18.067108264281742, "NOVONORM": 3.409721139114368, "NOVORAPID": 3.0556670585330057, "OLANZAPINE": 1.4940072316944273, "OXYBUTYNIN": 2.1136027777281887, "RANOLAZINE": 2.56687880833589, "REPAGLINIDE": 17.689220306166497, "SIFROL": 2.637235467890542, "SPIRONOLACTONE": 3.736153846002881, "STALEVO": 1.8254506865083733, "TAMIFLU": 1.711236468071354, "UNSPECIFIED": 4.277647757322662, "XARELTO": 1.3501329840637393, "ZOSTAVAX": 1.401932311810359, "null": 3.132963184388722}
\ No newline at end of file
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5141.json
index a317e2c9872..8766ae3b342 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5141.json
@@ -1 +1 @@
-{"AIMOVIG": 57.030724371770056, "IBUPROFEN": 38.72505589940975, "null": 2.142964164603532}
\ No newline at end of file
+{"COMIRNATY": 0.7176314166912728, "null": 1.2065275361315324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5142.json
index c234435e070..e8ff3c5ce98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5142.json
@@ -1 +1 @@
-{"BYETTA": 55.72367560562081, "TRULICITY": 50.0158035998072, "VICTOZA": 180.5402773475419}
\ No newline at end of file
+{"COMIRNATY": 0.3629267935515055, "FENTANYL": 10.545626881363622, "SPIKEVAX": 0.6749842316973602, "VAXZEVRIA": 0.7235664348371446, "null": 1.3879905858018269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5143.json
index 66e1f719ca3..c2d71ddace7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5143.json
@@ -1 +1 @@
-{"null": 2.151954624278827}
\ No newline at end of file
+{"ABATACEPT": 0.4528418798223143, "AIMOVIG": 0.8335443397287378, "ANAKINRA": 1.0344309596227224, "ANORO": 3.4749107087156177, "APIDRA": 2.3696678315432447, "ARAVA": 0.7872796118777242, "AUBAGIO": 1.056217489277387, "AVAMYS": 5.885870431432305, "AVANDIA": 0.3992803872261138, "AZOPT": 22.032096395214975, "BEOVU": 4.8270793968633, "BETMIGA": 3.0240552842945814, "BIKTARVY": 2.201854598827318, "BRINTELLIX": 0.6915199096042077, "BUDESONIDE": 0.8634564960446799, "BYDUREON": 1.016303927989168, "BYETTA": 1.66307223833574, "CELECOXIB": 11.661514749400643, "CELSENTRI": 18.365198130685133, "CICLOSPORIN": 0.4912136169779765, "CIMZIA": 1.8301810825183624, "COAPROVEL": 1.740136779983078, "COMBIVIR": 1.5751843882039276, "COMIRNATY": 0.089219946782068, "CYMBALTA": 2.682118682371012, "CYTARABINE": 0.6661267888978256, "DEXAMETHASONE": 0.9383455636021863, "DULAGLUTIDE": 5.539507622759449, "ELIQUIS": 1.7514694738714325, "ENBREL": 1.5075882364833388, "EVISTA": 2.0932913185675126, "EXFORGE": 1.8079287799975805, "EYLEA": 5.143439430619032, "FASENRA": 0.9132911386703902, "FENTANYL": 0.4639396343400573, "FLUTICASONE": 3.826825285078561, "FORSTEO": 0.5267823639020013, "GLYCOPYRRONIUM": 12.489912142733584, "HUMALOG": 7.709389007178751, "HUMIRA": 0.6223208088949505, "IBRANCE": 0.7551811379145577, "INCRUSE": 10.181196200405982, "INSULIN": 1.875621069833292, "JANUMET": 2.53970957903969, "JANUVIA": 3.5678032952166734, "JARDIANCE": 0.7529058911137463, "KEPPRA": 0.3863744281781209, "LANTUS": 7.999546670658191, "LEVEMIR": 3.940642164446946, "LYRICA": 0.6409596314426291, "MEPOLIZUMAB": 8.802340678641276, "METHOTREXATE": 0.4364114418454826, "MICARDIS": 1.085002945325752, "NAGLAZYME": 2.1359201923771782, "NEVANAC": 16.039538818856528, "NUCALA": 3.116719346550308, "PEGASYS": 0.4596979155870515, "PEGINTRON": 0.700169337484663, "PLAVIX": 0.3514031895475151, "RELVAR": 7.035630884168263, "SIMPONI": 1.474299904142406, "SPIKEVAX": 0.06798826012218, "SPRYCEL": 1.0481084739618722, "STELARA": 0.3618000009110921, "SUBOXONE": 0.5971554543536505, "TASIGNA": 1.044662851809221, "TOUJEO": 3.3578785022059754, "TOVIAZ": 7.079840221839622, "TOZINAMERAN": 0.1863363297608491, "TRELEGY": 7.7005673796594385, "TRULICITY": 1.536407643811229, "VAXZEVRIA": 0.045469361312886, "VFEND": 0.8774783776905762, "VIAGRA": 6.628713638373988, "VICTOZA": 1.3342525167493131, "XELJANZ": 2.3799662718851518, "XOLAIR": 0.381696713329175, "XTANDI": 0.5899374711500452, "ZOSTAVAX": 6.03222335674307, "ZYPREXA": 1.4968745518182374, "null": 1.879896120051616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5144.json
index 870aa793818..c0a5e9f5891 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5144.json
@@ -1 +1 @@
-{"THIOTEPA": 2815.918222338205, "null": 1.0432453016274748}
\ No newline at end of file
+{"JANUMET": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5145.json
index 4ee6c2fbb77..23490b35171 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5145.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 7.53600144829206, "OLANZAPINE": 9.863359753195429, "OXYBUTYNIN": 46.68457477866456, "null": 2.325530409594286}
\ No newline at end of file
+{"null": 1.7100643239240485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5146.json
index 3d16409e16e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5146.json
@@ -1 +1 @@
-{"NPLATE": 116.04096468830942}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5147.json
index d71e45d61c9..e332faf540f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5147.json
@@ -1 +1 @@
-{"ZOSTAVAX": 32.0153541750301, "null": 1.0604721639336117}
\ No newline at end of file
+{"NUBEQA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5148.json
index 3ea679ab7e4..186166c1903 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5148.json
@@ -1 +1 @@
-{"OLANZAPINE": 45.43331266053788}
\ No newline at end of file
+{"BEVACIZUMAB": 12.375672133402112, "COMIRNATY": 0.3926321267167268, "ELIQUIS": 2.326199819767089, "KEPPRA": 13.130619227214034, "SPIKEVAX": 0.2858408248108153, "STELARA": 3.913655833938604, "TEMODAL": 117.97095157262052, "TEMOZOLOMIDE": 355.40828063677634, "null": 0.4330976770974318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5149.json
index 92a53fce5be..8f1a7f241b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5149.json
@@ -1 +1 @@
-{"ALIMTA": 1.0322117420693044, "APIXABAN": 1.1002048630528467, "APREPITANT": 1.1563524352808996, "ARIXTRA": 9.260221237153402, "ATAZANAVIR": 1.4528998042638688, "AVASTIN": 2.069628089556249, "BLINCYTO": 9.931077907835238, "BRAFTOVI": 2.2814799737424134, "BRILIQUE": 20.4410477782199, "CELECOXIB": 1.0034198453060392, "CLOPIDOGREL": 40.16938217847586, "DEFITELIO": 11.40631664311037, "DUOPLAVIN": 19.36354366868858, "EFIENT": 21.784002915417467, "ELIQUIS": 12.89642416117359, "ENOXAPARIN": 10.122748293920669, "EXJADE": 1.4839212663259522, "EXVIERA": 1.6299895352005307, "FEBUXOSTAT": 2.226279260344153, "IBUPROFEN": 1.8712349673009367, "INTEGRILIN": 4.657665409948859, "ISCOVER": 28.611045219608908, "JEVTANA": 1.878672085496396, "LENVIMA": 1.2549472468168674, "LIXIANA": 20.43457538005694, "NEXAVAR": 5.33317546389968, "PLAVIX": 28.27726551692328, "PRADAXA": 16.646433690855105, "PRASUGREL": 12.140570065458991, "PRAXBIND": 9.138734031875424, "REBETOL": 1.1399129794074676, "RIVAROXABAN": 7.669519975721385, "RUXOLITINIB": 2.128013885062618, "SOVALDI": 1.3195603984250113, "SPIRONOLACTONE": 1.6461907145218275, "SPRYCEL": 1.3043098814881735, "STIVARGA": 2.815867544417741, "TAMIFLU": 3.950543936748369, "TICAGRELOR": 59.43854388157198, "TORISEL": 1.2406013587821048, "XARELTO": 9.831445625659468, "null": 1.5591320516289715}
\ No newline at end of file
+{"ASPARAGINASE": 76.12593055161321, "KEPPRA": 14.246605441202384, "TEMODAL": 115.2803270972064, "TEMOZOLOMIDE": 250.3005974242701, "null": 0.520639005259478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/515.json
index ecbb1681056..f39cc6c999f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/515.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/515.json
@@ -1 +1 @@
-{"ABILIFY": 66.62300005378003, "null": 3.967075970378113}
\ No newline at end of file
+{"ABACAVIR": 0.6003140989261265, "ABASAGLAR": 0.8334817100384813, "ABATACEPT": 5.917278702494962, "ABILIFY": 0.9559327567741912, "ADALIMUMAB": 4.040294810551348, "ADCIRCA": 0.915148482468812, "AERIUS": 1.4455240442967066, "AFINITOR": 0.2355766756817248, "AIMOVIG": 1.3744293214374503, "ALISKIREN": 7.829551754069855, "ALL": 2.722934579715965, "AMINOSALICYLIC": 3.808849611886302, "APIDRA": 0.4493095998675681, "APIXABAN": 6.752470954741497, "APREMILAST": 11.50680238375522, "ARAVA": 0.3187578170976297, "ARIPIPRAZOLE": 0.550538856358314, "ATAZANAVIR": 0.4548627950215135, "ATRIPLA": 0.126742627656366, "AUBAGIO": 0.8622969561245193, "AVAMYS": 0.2255308951524672, "AVANDAMET": 2.891006817442729, "AVANDIA": 2.463285906066578, "AVASTIN": 0.3270969467628445, "BENLYSTA": 1.2722785763164837, "BIKTARVY": 0.5874979003740401, "BOSULIF": 0.743870245847193, "BRILIQUE": 0.2735374276231051, "BRINTELLIX": 1.0278763466470164, "BRIVIACT": 1.6711991477861812, "BUMETANIDE": 3.889045767515914, "BUPIVACAINE": 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1.5105624892866487, "SILDENAFIL": 0.5741842128050759, "SIMPONI": 0.2724604998934644, "SPIKEVAX": 0.3938957876464821, "SPRYCEL": 0.5535647604713537, "STELARA": 0.4998707268198044, "STIVARGA": 0.3794625707915914, "STRIBILD": 0.1355422292378039, "SUBOXONE": 1.195523314022546, "SUBSTANCE": 58.49653583304914, "SUTENT": 0.6677281577452597, "TAMIFLU": 1.8498221583806345, "TASIGNA": 0.5454694419668381, "TIVICAY": 2.595667529497314, "TOVIAZ": 1.2318523277702245, "TOZINAMERAN": 0.8027211205698985, "TRACLEER": 0.2386999761432621, "TRELEGY": 0.8398586127987661, "TRULICITY": 0.8017036977406032, "TRUVADA": 0.1044314194280789, "TWINRIX": 0.4518832925537844, "ULTIBRO": 9.285647470349865, "VAXZEVRIA": 0.4375226699361905, "VFEND": 0.7537308577987979, "VIAGRA": 2.182108693692677, "VIMPAT": 4.040217485068628, "VOTRIENT": 0.6859159549500228, "XELJANZ": 0.7009978752351228, "XOLAIR": 0.3632012507940844, "XTANDI": 2.4786911840725074, "XYREM": 2.1995343898763675, "ZOSTAVAX": 0.8425501742442659, "ZYPADHERA": 2.9605379745798617, "ZYPREXA": 1.2571967014560936, "null": 1.5393130592207869}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5150.json
index c6e6655c28f..9de0305f4d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5150.json
@@ -1 +1 @@
-{"BRAFTOVI": 30.444162681138355, "CIALIS": 55.802230110504254, "COSENTYX": 6.958519350054344, "ELIQUIS": 1.2783529909268834, "ENBREL": 5.284586953967684, "GARDASIL": 2.052637310544196, "MEKINIST": 6.2175471404663565, "PEGASYS": 1.2444027046616473, "ROACTEMRA": 4.603834993479543, "SIMPONI": 5.80786831435327, "XELJANZ": 1.529583835907429, "ZELBORAF": 61.79864680335034, "ZOSTAVAX": 10.73653273248661}
\ No newline at end of file
+{"KEPPRA": 10.191694057385243, "MEKINIST": 40.072743996917694, "null": 0.5352117695574716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5151.json
index 951ca5f804a..b49973be1eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5151.json
@@ -1 +1 @@
-{"CIALIS": 467.9892252687633, "DABRAFENIB": 101.38713681701633, "IPILIMUMAB": 40.76271445567616, "KEYTRUDA": 19.4419816727237, "MEKINIST": 153.2119819876857}
\ No newline at end of file
+{"null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5152.json
index a8791eb1b8a..373ff628410 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5152.json
@@ -1 +1 @@
-{"null": 3.4178729931212524}
\ No newline at end of file
+{"COMIRNATY": 0.3422267187328554, "null": 0.7890198655729873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5153.json
index 30a8d3be56f..53e8da31e62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5153.json
@@ -1 +1 @@
-{"ABATACEPT": 1.8931803076357276, "ABILIFY": 3.134575846333691, "ACE": 5.312704066005202, "ADCIRCA": 1.1607455286732558, "AIMOVIG": 6.244432116238149, "AMBRISENTAN": 2.550416963317032, "ANTIBIOTICS": 2.291643309185935, "APIXABAN": 3.247522042183846, "APREMILAST": 3.471302949247177, "ARIPIPRAZOLE": 1.1350349767765324, "AUBAGIO": 3.971943006931743, "AVAMYS": 1.554432068175652, "AVONEX": 3.118720419413033, "AZILECT": 1.9693778359268224, "BENLYSTA": 1.496668844976453, "BETAFERON": 1.0097081371701282, "BOSULIF": 1.5269239454278023, "BRINTELLIX": 1.2152245149417036, "BRIVARACETAM": 6.0700529536339065, "BRIVIACT": 2.874098043810729, "BUPIVACAINE": 1.1490448028393203, "BUPRENORPHINE": 1.2352126628881686, "BYDUREON": 2.089332292815164, "CHAMPIX": 2.9491196392023493, "COMBIVIR": 1.1020985967961126, "CYMBALTA": 2.846944378320692, "DAKLINZA": 1.2673151606101074, "DULAGLUTIDE": 1.6814026929600046, "DULOXETINE": 1.8532812843814328, "ELIQUIS": 1.1641723111519136, "ENTACAPONE": 1.2367124654788253, "ENTRESTO": 1.1876103520353314, "ENZALUTAMIDE": 1.5542455318180413, "ERELZI": 2.0708032605516005, "ERENUMAB": 1.3088846498189368, "EUCREAS": 1.3452810623236893, "EXELON": 3.766492137692678, "EXFORGE": 1.1171060753841606, "FAMPYRA": 1.5759203493049605, "FYCOMPA": 1.4876169205062035, "GALAFOLD": 1.84184355377395, "GARDASIL": 2.820406397776104, "GILENYA": 2.5974757118218323, "HUMALOG": 4.055099621342925, "HYDROCORTISONE": 1.2863022332576242, "IBRANCE": 3.124955162588955, "INLYTA": 1.0732946011476496, "INSULIN": 1.210641363555797, "KAFTRIO": 1.5918724832766704, "KEPPRA": 3.315903651478308, "LACOSAMIDE": 1.791207143919241, "LANTUS": 2.296339684344088, "LATUDA": 1.8636675538774456, "LEVEMIR": 1.157732822931254, "LEVETIRACETAM": 2.415526318538046, "LUPKYNIS": 2.151472970190159, "LYRICA": 4.22556505262172, "LYSODREN": 3.0518598258782337, "MELATONIN": 2.472631349724021, "NINLARO": 1.6420912340991178, "OCRELIZUMAB": 4.090194422574117, "OLANZAPINE": 1.104349664378096, "OLYSIO": 1.7952836919304958, "ORENCIA": 2.084766456628006, "OZEMPIC": 5.183641924205403, "PEGASYS": 2.35219547194414, "PEGINTRON": 2.933787384267375, "PLEGRIDY": 2.0043152743431447, "POPPERS": 22.02625791205271, "PRIALT": 4.426920092772397, "PROTELOS": 2.632380138363757, "REVATIO": 1.2366592622293922, "RISPERIDONE": 1.4750910722219326, "SIFROL": 1.1251460662537485, "SOVALDI": 1.0594751386868426, "TAMIFLU": 1.2609268597400087, "TECFIDERA": 6.514345875131827, "TERIFLUNOMIDE": 3.1825561538104483, "TOUJEO": 1.4705002302016263, "TOVIAZ": 3.3007688490311677, "TRULICITY": 1.1336205398791064, "VARENICLINE": 1.827227839152326, "VFEND": 1.1682692332355316, "VIAGRA": 1.7300249677154902, "VIMPAT": 3.4185507630444425, "XELJANZ": 2.848906966970412, "XTANDI": 3.0024892426353595, "XYREM": 3.484801502040036, "YESCARTA": 2.343798909178276, "ZYPADHERA": 1.0547316501059112, "ZYPREXA": 1.163698068475805, "null": 1.2889387049677383}
\ No newline at end of file
+{"GALAFOLD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5154.json
index 6e83a234759..53e8da31e62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5154.json
@@ -1 +1 @@
-{"COMIRNATY": 11.58258423488003}
\ No newline at end of file
+{"GALAFOLD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5155.json
index fb143a16ff3..53e8da31e62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5155.json
@@ -1 +1 @@
-{"ACLIDINIUM": 34.264617464400864, "COMIRNATY": 1.654118471542514, "KEPPRA": 1.6499396278600185, "SPIKEVAX": 1.1679976292837906, "TOZINAMERAN": 1.7942251931630464, "ZOSTAVAX": 4.372665369048065}
\ No newline at end of file
+{"GALAFOLD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5156.json
index 25048ed7c41..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5156.json
@@ -1 +1 @@
-{"PRIVIGEN": 51.82943737253477, "null": 1.2751951137186257}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5157.json
index 06bdcab827d..3a1e4dbb2e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5157.json
@@ -1 +1 @@
-{"KEPPRA": 5.428264388703753, "LANTUS": 1.1274065049817394, "NUTROPIN": 137.41681124373372, "SOMATROPIN": 56.60556288884906, "STELARA": 3.267509000760177, "XOLAIR": 1.8700445815549347, "ZOSTAVAX": 1.8584933694745944, "null": 3.155245049152494}
\ No newline at end of file
+{"VIREAD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5158.json
index db2dcae05f9..2c8710ccabb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5158.json
@@ -1 +1 @@
-{"null": 1.7699517587271436}
\ No newline at end of file
+{"null": 0.2636835288886316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5159.json
index cbb9a2cda05..e528cbcd87f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5159.json
@@ -1 +1 @@
-{"CICLOSPORIN": 2.3666851241929243, "COMIRNATY": 1.0364799197146817, "GARDASIL": 5.627798572035309, "MMRVAXPRO": 3.955422373628032, "NIMENRIX": 16.035210660767962, "PRIVIGEN": 43.225935869015366, "VAXZEVRIA": 2.194724300455667, "null": 1.417229363862565}
\ No newline at end of file
+{"ARIPIPRAZOLE": 138.1780621387131, "FENTANYL": 26.91985384191952, "null": 0.3511249500169788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/516.json
index c82dd5e0279..dc546b110ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/516.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/516.json
@@ -1 +1 @@
-{"null": 4.802594096429057}
\ No newline at end of file
+{"COMIRNATY": 1.408758404126483, "SPIKEVAX": 0.6626502836068203, "VAXZEVRIA": 0.3618765920780917, "null": 1.037094337686606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5160.json
index 752c096cbe9..0e32b732408 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5160.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 3.650332361743743, "AZACITIDINE": 11.329537963438954, "BENLYSTA": 2.146702973141024, "BEXSERO": 12.117142794974749, "BUMETANIDE": 24.377082120436363, "CELLCEPT": 2.1292880044485374, "CIMZIA": 2.308196561470091, "CYTARABINE": 1.802007344160923, "DEXAMETHASONE": 2.8334366671711573, "ENBREL": 1.1291826529866549, "GARDASIL": 1.920125085633452, "HIZENTRA": 4.4043238105405536, "HUMAN": 3.0835514355770166, "INFANRIX": 12.069120941351851, "IPILIMUMAB": 3.548983673908793, "IRON": 8.871124926098295, "KEPPRA": 1.342676448413834, "KEYTRUDA": 4.869034976549676, "KIOVIG": 12.883176172319638, "MEKINIST": 2.324092423199864, "METHOTREXATE": 1.9346616583457912, "NIMENRIX": 3.128265998765871, "OPDIVO": 4.957867972420475, "PEGINTERFERON": 1.8870471760691736, "PEGINTRON": 1.218573333151925, "PRIVIGEN": 6.605751755991852, "RINVOQ": 3.885957320941921, "RITUXIMAB": 1.987599251850224, "ROACTEMRA": 2.9906611078709435, "ROTATEQ": 3.6612257708683407, "SOLIRIS": 6.487533766053176, "SPINRAZA": 10.622511670869004, "STELARA": 1.7257788898019957, "TAMIFLU": 2.1985142309196237, "TWINRIX": 5.9297707516085385, "VFEND": 2.337675901633092, "XELJANZ": 1.308818005762802, "YERVOY": 6.01690293636279, "null": 1.144986682646001}
\ No newline at end of file
+{"ATRIPLA": 29.376101713647127, "ELIQUIS": 1.1225227858958209, "ENTRESTO": 4.997079519827066, "FORXIGA": 6.045588894643836, "HUMIRA": 3.7057653826172894, "JARDIANCE": 8.888497178933218, "KALETRA": 6.5503082776078925, "STRIBILD": 19.99977407824438, "TRUVADA": 34.19553337255382, "VIREAD": 8.336870075297226, "null": 0.1426491176920866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5161.json
index e488a4c56e8..8ddf842d6c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5161.json
@@ -1 +1 @@
-{"BRAFTOVI": 3.761054922071707, "CELLCEPT": 1.4033736083323798, "FLEBOGAMMA": 110.00785822130943, "HIZENTRA": 42.02005390010969, "HUMAN": 102.35111657517828, "HYQVIA": 39.738901622563006, "IPILIMUMAB": 8.047001915998338, "KEYTRUDA": 2.462047793821412, "KIOVIG": 120.66271390629689, "MEKINIST": 1.5967870491710567, "OPDIVO": 9.269458446645515, "PRIVIGEN": 180.9170365490505, "SPINRAZA": 15.887930131253365, "TELMISARTAN": 12.6570295587455, "null": 1.5468329662804474}
\ No newline at end of file
+{"ABACAVIR": 1.0865611458922164, "AFINITOR": 2.0122021094934275, "ALIMTA": 0.9030895870714832, "ALPELISIB": 8.32963304444604, "APIXABAN": 0.6595255548853167, "ARAVA": 0.423956465482624, "ARIPIPRAZOLE": 2.9899077985654694, "ATAZANAVIR": 3.496509708654596, "ATRIPLA": 4.832647256171353, "BIKTARVY": 10.884422190208015, "BUMETANIDE": 5.943983092291953, "BYDUREON": 0.90669990283803, "BYETTA": 1.339255004579943, "CICLOSPORIN": 3.0078259372301943, "CLOPIDOGREL": 1.7997369464969062, "COMIRNATY": 0.0818958062173344, "COSENTYX": 0.9154863204490834, "CUBICIN": 1.85377516161719, "CYMBALTA": 0.1465933027344858, "DAPAGLIFLOZIN": 8.49638488109364, "EDURANT": 27.643554080405792, "ELIQUIS": 1.355129565640815, "EMPAGLIFLOZIN": 11.458758221066695, "EMTRICITABINE": 11.217394176131512, "ENTRESTO": 35.55669847920228, "EPCLUSA": 5.476512084250556, "EXFORGE": 1.6759591669513356, "EXJADE": 5.954876076476644, "FORSTEO": 0.3604287053445265, "FORXIGA": 37.225351671922496, "FULVESTRANT": 2.385440591880667, "GALAFOLD": 21.12201785750508, "GENVOYA": 11.564132450969906, "HARVONI": 9.59118611304434, "HEPSERA": 9.909123720359222, "HUMALOG": 0.4276729565390301, "HUMIRA": 1.244514296707225, "IBRANCE": 0.8622346350552086, "IBUPROFEN": 0.9964580681296956, "INCIVO": 1.0046085575652677, "INSULIN": 1.4620542860790264, "IVABRADINE": 26.640445622249874, "JAKAVI": 2.739039268546146, "JANUMET": 1.1712098366378996, "JANUVIA": 1.4688601935296977, "JARDIANCE": 17.194474165429988, "KEYTRUDA": 0.2583402086205117, "KISQALI": 2.372394845257269, "KYMRIAH": 1.5709820165824904, "LANTUS": 0.2119760042517864, "LIXIANA": 5.076442554601303, "LUPKYNIS": 54.10652661597313, "LYNPARZA": 3.350114791446407, "LYRICA": 0.8976593586554257, "METFORMIN": 3.82382876781628, "MICARDIS": 1.010844259592957, "MULTAQ": 10.712231050801597, "PEGASYS": 0.1291377096252343, "PEGINTERFERON": 2.972268343849347, "PEMETREXED": 2.3813590387932786, "RANEXA": 6.02218835659011, "RASILEZ": 14.738760835681012, "REBETOL": 3.2845716783947854, "REMDESIVIR": 14.218054002144711, "REYATAZ": 4.208226432560288, "RUBRACA": 4.193727772477089, "SAMSCA": 10.993233127056232, "SOLIRIS": 2.4095523909266183, "SOVALDI": 4.504709760160125, "SPIKEVAX": 0.0740711207922719, "SPIRONOLACTONE": 3.4408901559498477, "STRIBILD": 7.059146965188791, "SUTENT": 0.4394644400641119, "TASIGNA": 1.288380348158089, "TENOFOVIR": 26.25382620265648, "TIVICAY": 4.202684904602609, "TOZINAMERAN": 0.1838862762229045, "TRULICITY": 4.345697265948747, "TRUVADA": 5.544934713583113, "VALSARTAN": 12.168385066272046, "VAXZEVRIA": 0.0115893194691754, "VICTOZA": 1.281289678260023, "VIREAD": 7.780712543780693, "VOTRIENT": 0.747367237370399, "XARELTO": 1.9222208599925448, "XELJANZ": 0.6200069453698855, "ZOSTAVAX": 0.4298012829412424, "null": 0.5642656475231355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5162.json
index 5519b22065c..3d475359a02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5162.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 12.982161620973324, "FENTANYL": 4.975531752367867, "KEPPRA": 3.8921821733887274, "MELPHALAN": 54.39845061524957, "PEGINTRON": 3.074499234801986, "RELVAR": 78.16649334527607, "SPINRAZA": 40.26448965100187}
\ No newline at end of file
+{"ATRIPLA": 9.138976620101262, "COMIRNATY": 0.1146447042706558, "DAPAGLIFLOZIN": 115.4869166457034, "ENTRESTO": 9.25722964247403, "JARDIANCE": 10.05094202203462, "STRIBILD": 11.120092820898366, "TRUVADA": 19.96672116034269, "null": 0.2187449697407686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5163.json
index 3b8d5673ba3..072dbcfda15 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5163.json
@@ -1 +1 @@
-{"SPINRAZA": 162.41417442634565, "null": 2.216989853625224}
\ No newline at end of file
+{"SPIKEVAX": 16.23246180124599}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5164.json
index daa1e2edf93..74ff46df5c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5164.json
@@ -1 +1 @@
-{"ATAZANAVIR": 24.8479624139308, "BIKTARVY": 22.12526967402916, "CELLCEPT": 18.6082643096074, "CICLOSPORIN": 7.022672108143361, "DEXAMETHASONE": 7.818018911247948, "EFAVIRENZ": 94.03975606283969, "EMTRICITABINE": 57.65008032027289, "KALETRA": 16.869321207753014, "LAMIVUDINE": 108.48959861935464}
\ No newline at end of file
+{"CICLOSPORIN": 39.4835916661227, "null": 0.8565727309887768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5165.json
index 8ddce86d009..fbc6d8a1e23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5165.json
@@ -1 +1 @@
-{"LEMTRADA": 143.63200416987397}
\ No newline at end of file
+{"ATRIPLA": 0.7277583627179474, "CELLCEPT": 3.091229221506835, "CICLOSPORIN": 5.566138618323351, "COMIRNATY": 0.5395064036301686, "IPILIMUMAB": 11.684935902526489, "KEYTRUDA": 1.7918667092344174, "PEGASYS": 0.8934740380677415, "SIMPONI": 4.571076360576318, "SOLIRIS": 4.512951320548305, "SPIKEVAX": 0.4741063336743211, "SUTENT": 0.7776654382967126, "TOZINAMERAN": 0.8949839026268578, "VAXZEVRIA": 0.1095501304168309, "null": 1.0628513183686044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5166.json
index b9e83b03360..6a26692fe76 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5166.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 58.2547894768026, "MENVEO": 135.67257430230964, "SOLIRIS": 111.5718939991666, "null": 1.6529040897327385}
\ No newline at end of file
+{"COMIRNATY": 0.2687393603707121, "CUBICIN": 80.43272265657906, "null": 0.922741215011107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5167.json
index b2e7b6bb632..4c2de3aa6b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5167.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"COMIRNATY": 0.4972471818645569, "null": 1.0738417992000802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5168.json
index 71f20c07950..3f5429fe2f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5168.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 85.5928231358192, "AMINOSALICYLIC": 75.855969798588, "BEDAQUILINE": 71.92468919821913, "BUSULFAN": 22.12015713521552, "CICLOSPORIN": 7.09766852481623, "COMBIVIR": 29.838379456352666, "DEXAMETHASONE": 26.543622274472067, "EFAVIRENZ": 48.183797260451534, "FILGRASTIM": 94.97647903946046}
\ No newline at end of file
+{"CELLCEPT": 14.033426820952116, "CICLOSPORIN": 11.323459240980338, "SOLIRIS": 30.2219430048036, "null": 0.4456636419931546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5169.json
index 30ce107dfe1..b5a94b82cb5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5169.json
@@ -1 +1 @@
-{"ABACAVIR": 7.782808416034403, "ALEMTUZUMAB": 19.08377803895416, "CELLCEPT": 7.48594216551238, "CIMZIA": 1.8082502294441825, "GARDASIL": 3.2392127816267102, "INTEGRILIN": 96.46591368346768, "PEGASYS": 2.343774189009945}
\ No newline at end of file
+{"ATRIPLA": 1.2126636906635726, "BUSULFAN": 25.546498975002923, "CELLCEPT": 6.078360609471277, "CICLOSPORIN": 15.36820401466257, "COMIRNATY": 0.3272985342330487, "IBUPROFEN": 7.434827410278267, "KEYTRUDA": 3.1838216115646825, "SPIKEVAX": 0.4011163237956292, "TOZINAMERAN": 0.9369515761955084, "null": 0.810917504517299}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/517.json
index 624170e33ad..c96757ddb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/517.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/517.json
@@ -1 +1 @@
-{"null": 1.731601702195374}
\ No newline at end of file
+{"null": 1.2000579486555316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5170.json
index 642b8c4b3c1..324f6825d6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5170.json
@@ -1 +1 @@
-{"null": 3.226473374678685}
\ No newline at end of file
+{"ATRIPLA": 1.4853090654075778, "CICLOSPORIN": 20.173059515114243, "COMIRNATY": 1.01035574391326, "SPIKEVAX": 1.0387043574713943, "TOZINAMERAN": 4.624798922546271, "VAXZEVRIA": 0.4168156504329136, "null": 0.5287066960519344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5171.json
index 5153dfbbe0a..1ae7ebfcdaa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5171.json
@@ -1 +1 @@
-{"BEXSERO": 447.5382783503141, "SOLIRIS": 207.8043086040115}
\ No newline at end of file
+{"null": 1.1189131890781991}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5172.json
index 2515a13e7fc..08b8c0b59c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5172.json
@@ -1 +1 @@
-{"SOLIRIS": 242.7543101087164, "null": 1.631140917454479}
\ No newline at end of file
+{"COMIRNATY": 0.2618137088557677, "KEYTRUDA": 5.414875226241813, "SIMPONI": 6.4786283952236605, "SPIKEVAX": 0.8167245698739698, "TOZINAMERAN": 1.375089378631499, "VAXZEVRIA": 0.1920953446137341, "null": 1.3969727902934057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5173.json
index 89fe47c45f1..4099e08a2a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5173.json
@@ -1 +1 @@
-{"MENVEO": 232.4328799216312, "SOLIRIS": 335.3369801704848}
\ No newline at end of file
+{"CICLOSPORIN": 40.79378178339435, "null": 0.594660458766305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5174.json
index 00b171e0bf1..ec01c8bb02a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5174.json
@@ -1 +1 @@
-{"COMBIVIR": 53.79285941713882, "null": 4.76877766187732}
\ No newline at end of file
+{"BASILIXIMAB": 151.73728268961497, "CICLOSPORIN": 30.503864489519064, "SOLIRIS": 14.064299512472532, "null": 1.116768885313567}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5175.json
index ee4e8dddd95..b8c10738718 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5175.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0673023049304051}
\ No newline at end of file
+{"CHAMPIX": 2.463127733345117, "COMIRNATY": 0.4236582746005604, "COSENTYX": 1.8674412213150413, "CYMBALTA": 0.6112557845412172, "IBRANCE": 0.8845802012906498, "INLYTA": 4.033188573388499, "IRESSA": 7.513602512433928, "KEYTRUDA": 1.6334485338776628, "NEXAVAR": 2.618656485935144, "PEGASYS": 1.1460043907836286, "PEGINTRON": 1.9876408924373528, "SPIKEVAX": 0.2233716431153286, "STIVARGA": 2.8679538698210845, "SUTENT": 5.439892588161064, "TOZINAMERAN": 0.6121973132958124, "VAXZEVRIA": 0.2335915117208148, "null": 2.24762552469664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5176.json
index 7b7ef597bed..128e494fe25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5176.json
@@ -1 +1 @@
-{"ELIQUIS": 10.418608019474334, "PLAVIX": 20.7498074890058}
\ No newline at end of file
+{"ABATACEPT": 12.545508815812305, "ACETAMINOPHEN": 26.077630807602503, "ADALIMUMAB": 25.24085094901, "AFINITOR": 0.4948445958231805, "AMINOSALICYLIC": 1.180698046079092, "APREMILAST": 5.044314927048245, "APREPITANT": 31.26092587474628, "ARAVA": 47.29109702107069, "BUPRENORPHINE": 0.2391270465312627, "CABOMETYX": 0.9168577360117636, "CERTOLIZUMAB": 7.101370809522758, "CHAMPIX": 0.188379325893518, "CIMZIA": 3.538408502972722, "COMIRNATY": 0.1380175552865932, "COSENTYX": 0.6542985532391166, "CYMBALTA": 0.1275564843143791, "ELIQUIS": 0.0761813577661436, "ERELZI": 4.2271358903615335, "IBRANCE": 0.5233671986673402, "IBUPROFEN": 0.2114619327287821, "INLYTA": 1.2879185217479745, "LENVIMA": 0.5553555657911026, "NEXAVAR": 0.8424997777389651, "PEGASYS": 0.5511036738628763, "PEGINTERFERON": 0.7285312766777952, "PEGINTRON": 0.3224054264598061, "RELVAR": 0.8918595135023857, "RITUXIMAB": 1.7795798305934494, "SPIKEVAX": 0.1062219425215546, "STIVARGA": 0.2100023385937134, "SUBOXONE": 0.355525303952687, "SUTENT": 3.8732505966282864, "TOZINAMERAN": 0.3391442185484765, "VAXZEVRIA": 0.1479313155645391, "VOTRIENT": 0.4708541151657929, "XELJANZ": 0.1323136191966613, "null": 0.2318303826631698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5177.json
index df212e85a8e..24cafa72189 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5177.json
@@ -1 +1 @@
-{"ATRIPLA": 1.0239590992189556, "CIMZIA": 1.0274051704479903, "COSENTYX": 4.474738329991791, "CYMBALTA": 1.043837572948883, "ELIQUIS": 2.5984031762032744, "ENTRESTO": 2.832516971038215, "HUMALOG": 2.4132122228082467, "LANTUS": 1.5517998249788325, "LEVOFLOXACIN": 2.309812339610075, "OZEMPIC": 62.46572376117647, "PEGASYS": 1.431685268360572, "SIMPONI": 3.197942813221633, "STELARA": 2.159682843530743, "STRIBILD": 2.8838998318480638, "TRUVADA": 1.0257513898691, "VIAGRA": 4.307880722785227, "XELJANZ": 5.274771973456831, "ZOSTAVAX": 4.731643656075844, "null": 1.464556553427777}
\ No newline at end of file
+{"FENTANYL": 13.437854818654188, "null": 4.7644925028882215}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5178.json
index 26670cbf2ae..757ee145c57 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5178.json
@@ -1 +1 @@
-{"COMIRNATY": 14.867551134262436, "ESMYA": 15.82191013257609, "SPIKEVAX": 2.391940829647871}
\ No newline at end of file
+{"IPILIMUMAB": 93.33687687709478, "KEYTRUDA": 29.365829221533048, "OPDIVO": 27.08891849697116, "null": 0.4950149342157043}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5179.json
index 3e0dbc47cbe..f1e724f8d20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5179.json
@@ -1 +1 @@
-{"AIMOVIG": 3.506349710630265, "ALLI": 173.7794336599358, "BIKTARVY": 30.25483376445725, "COMIRNATY": 1.7522462280575228, "IBRANCE": 1.2578169909455086, "SPIKEVAX": 1.0121026257059598, "ZOSTAVAX": 5.313546838501924, "null": 1.3220811554473648}
\ No newline at end of file
+{"null": 1.6305801185912183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/518.json
index 4fc14dc8643..cf73911d6f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/518.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/518.json
@@ -1 +1 @@
-{"ZYPREXA": 16.890541440676117, "null": 5.497939411714516}
\ No newline at end of file
+{"null": 0.8623740905996042}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5180.json
index f7829b63cfc..f76b6289195 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5180.json
@@ -1 +1 @@
-{"ABILIFY": 4.8554980416227576, "AIMOVIG": 3.4660200546216697, "CIMZIA": 6.383010905401272, "COMIRNATY": 1.17774915859957, "COVID19": 1.36205144838144, "FASLODEX": 7.283634155248744, "TOZINAMERAN": 3.084408508421559, "ZOSTAVAX": 7.221315517760544}
\ No newline at end of file
+{"ABACAVIR": 5.069443730099772, "ABILIFY": 4.606368789970698, "AFINITOR": 3.191624683823824, "ANAKINRA": 21.94305978070569, "AZATHIOPRINE": 3.7608684675252255, "CHAMPIX": 1.1035543943181652, "CICLOSPORIN": 1.913302431378617, "CIMZIA": 1.0858525196814617, "COMIRNATY": 0.0802950837737942, "CYMBALTA": 1.4930527856981666, "GARDASIL": 1.4952724899757377, "HUMIRA": 6.596604427153548, "NUCALA": 3.800430589881909, "OLANZAPINE": 1.8423896882920976, "PASIREOTIDE": 115.57485983627264, "PLAVIX": 1.4264685066949645, "SOMATROPIN": 68.31341766630216, "TASIGNA": 3.887708493428753, "TOZINAMERAN": 0.2407748843071918, "ZOSTAVAX": 17.751548643631097, "ZYPREXA": 15.224548656496314, "null": 1.32737246957542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5181.json
index befb1d8c5df..9c680269e24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5181.json
@@ -1 +1 @@
-{"COMIRNATY": 2.66829793192535}
\ No newline at end of file
+{"SAQUINAVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5182.json
index 91f3e179785..e6f1387e436 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5182.json
@@ -1 +1 @@
-{"COMIRNATY": 16.876233111511485, "SPIKEVAX": 2.4609535884259084}
\ No newline at end of file
+{"null": 0.7428750911212086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5183.json
index 0f5f02459f6..5007bbe0dba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5183.json
@@ -1 +1 @@
-{"COMIRNATY": 20.68434401105291, "SPIKEVAX": 2.68963012723821}
\ No newline at end of file
+{"JARDIANCE": 28.113853905460807, "null": 1.0707578149250971}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5184.json
index 8987be66dab..64dad9d030d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5184.json
@@ -1 +1 @@
-{"COMIRNATY": 15.235498210707116, "ELLAONE": 2.977724608827629, "EVRA": 2.0428543868199105, "SPIKEVAX": 2.794989298768743, "TOZINAMERAN": 1.5074072711256288}
\ No newline at end of file
+{"CYMBALTA": 5.747781102950112, "FORXIGA": 47.28269332852632, "HEPSERA": 100.6072620648826, "JARDIANCE": 45.5475802846092, "OLANZAPINE": 4.3723505993512, "SUTENT": 1.2456016565905617, "ZYPREXA": 4.557271525088346, "null": 0.5434898091842607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5185.json
index d1ccb89d40f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5185.json
@@ -1 +1 @@
-{"COMIRNATY": 7.097310558455764}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5186.json
index 2f3b79d50f4..330a056bcdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5186.json
@@ -1 +1 @@
-{"COMIRNATY": 8.3983681665545, "COVID19": 2.80655562536948, "ELLAONE": 84.35303207001584, "EVRA": 1.2842858586025658, "SPIKEVAX": 2.151318453640999, "TOZINAMERAN": 4.0383497638216}
\ No newline at end of file
+{"TAGRISSO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5187.json
index 2daebba30be..147a1b46064 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5187.json
@@ -1 +1 @@
-{"COMIRNATY": 10.921590720679024, "COVID19": 1.1400386592292422, "ELLAONE": 2.1522009742812838, "EVRA": 1.149287614308465, "GARDASIL": 1.4627043614113897, "MAVENCLAD": 1.0917489089932753, "SPIKEVAX": 2.682871572706525, "TOZINAMERAN": 3.537129160155573}
\ No newline at end of file
+{"FASTURTEC": 995.870006735314, "HUMALOG": 95.23597343459136, "null": 0.3571088539563765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5188.json
index 1daa6ef2086..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5188.json
@@ -1 +1 @@
-{"COMIRNATY": 2.7592193060025574, "SPIKEVAX": 1.0727092548624304}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5189.json
index 4956017acff..3bf175fcd5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5189.json
@@ -1 +1 @@
-{"null": 3.21688923472569}
\ No newline at end of file
+{"ZYPREXA": 22.79795703353525, "null": 1.703387479893112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/519.json
index 6bf63252ebb..1d2974d9ec1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/519.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/519.json
@@ -1 +1 @@
-{"null": 2.882650336471254}
\ No newline at end of file
+{"null": 0.9615430346474086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5190.json
index 3e3307e023f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5190.json
@@ -1 +1 @@
-{"ABILIFY": 4.886333254395177, "AIMOVIG": 1.4146240703293926, "ANORO": 1.1852124055282327, "ARIPIPRAZOLE": 2.7768600865340187, "BEDAQUILINE": 1.2132827495258385, "BEVACIZUMAB": 1.4051802502892643, "BIKTARVY": 4.062789468605201, "BREXPIPRAZOLE": 33.24999593428197, "BRINTELLIX": 1.4569453245427375, "BRIVIACT": 3.498861890931292, "BUPRENORPHINE": 3.599401039950524, "CHAMPIX": 7.2335849714411795, "COMTAN": 1.4992517140193085, "COSENTYX": 1.0967294693572098, "CYMBALTA": 2.241759627222402, "DARUNAVIR": 2.070139029757534, "DELAMANID": 2.98590434709295, "DULOXETINE": 3.951452673353805, "EFAVIRENZ": 3.260110530908055, "ENTYVIO": 1.118918379457786, "EPCLUSA": 1.8210046280909264, "ERLEADA": 1.3304787590422638, "FAMPYRA": 3.166893017963858, "FENTANYL": 1.5599274857014032, "FIRDAPSE": 1.285527863123199, "FYCOMPA": 1.6730102440816408, "GARDASIL": 1.4179436040164626, "GENVOYA": 2.5728594074446365, "HUMALOG": 1.228578462849809, "INCIVO": 2.429141203861877, "INTRONA": 2.7581073436713144, "ISENTRESS": 1.4000287152550626, "IVABRADINE": 9.96525652703948, "KAFTRIO": 7.672477799744856, "KALYDECO": 4.193822873079055, "KEPPRA": 3.355723460706693, "LACOSAMIDE": 1.448301694202969, "LATUDA": 6.165308565013028, "LEVETIRACETAM": 2.439086821822709, "LEVOFLOXACIN": 1.975586454136864, "LOXAPINE": 9.37636320254358, "LYRICA": 1.5144310715136915, "MERCAPTOPURINE": 3.328053703309068, "NORVIR": 1.93718026878199, "NOT": 1.1949689661209553, "OLANZAPINE": 2.301161431964491, "OPTIMARK": 1.0381518508277732, "PANTOPRAZOLE": 7.765789611244798, "PEGASYS": 2.5043278693789026, "PEGINTERFERON": 3.125436440683549, "PEGINTRON": 3.084396250006178, "PLEGRIDY": 1.9094653497641865, "PREGABALIN": 1.1236965654596935, "RISPERIDONE": 2.4171961297892444, "SERTRALINE": 14.850121211582309, "SIFROL": 4.908716868074454, "SOVALDI": 1.2086107660680692, "STALEVO": 1.5021397953144502, "SUBOXONE": 4.072375292129225, "TAMIFLU": 4.953582762655146, "TIVICAY": 5.391991499208519, "TOVIAZ": 1.3766409473158308, "TRIUMEQ": 5.24950614546218, "TRULICITY": 1.1339127431692022, "VFEND": 8.103742127294886, "VIAGRA": 1.2626019298912046, "VIMPAT": 2.702442678953964, "VORICONAZOLE": 8.13225930813876, "XYREM": 1.2189310550008556, "ZYPREXA": 3.655220285092621, "null": 1.8733413868761368}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5191.json
index ec1ec066290..9b9968c69e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5191.json
@@ -1 +1 @@
-{"null": 1.1037392363797265}
\ No newline at end of file
+{"BEVACIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5192.json
index 9654214ab50..a0aefd2dde4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5192.json
@@ -1 +1 @@
-{"BRINTELLIX": 4.009657135944759, "COMIRNATY": 1.5765765005604249, "COVID19": 6.039446641253501, "SPIKEVAX": 1.1639244561352962, "TOZINAMERAN": 5.23567206909259, "VAXZEVRIA": 1.319279088721694}
\ No newline at end of file
+{"AFINITOR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5193.json
index ba47e144444..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5193.json
@@ -1 +1 @@
-{"ABILIFY": 3.039389038283853, "ACTOS": 3.008330778334653, "AIMOVIG": 1.8400605619318808, "ANORO": 1.7771432072839286, "ARIPIPRAZOLE": 4.027447556640392, "ASENAPINE": 26.26973011913314, "AUBAGIO": 2.142678966032652, "BENLYSTA": 2.480285546723076, "BENZODIAZEPINES": 18.375343974002057, "BUPRENORPHINE": 1.4604730491864553, "CARIPRAZINE": 22.61356722903168, "CHAMPIX": 3.59661557933796, "CYMBALTA": 1.6538273662976974, "DULOXETINE": 4.190555203252156, "FAMPYRA": 1.243570776859175, "FENTANYL": 3.650724815348212, "GARDASIL": 1.1742439541114136, "HUMALOG": 1.4413798604601156, "IBRANCE": 2.191403480274153, "INLYTA": 1.500131550892271, "KEPPRA": 2.7675201001747585, "LANTUS": 1.0741085923046818, "LATUDA": 5.767121979839229, "LEVETIRACETAM": 1.6463232818764333, "LYRICA": 2.8887378366452383, "MELATONIN": 1.9441686483860627, "OCRELIZUMAB": 7.43367500524008, "OLANZAPINE": 4.100979165589343, "OPTIMARK": 24.285711687637445, "OZEMPIC": 12.690196665574875, "PANTOPRAZOLE": 2.60990286126989, "PEGASYS": 1.4921369285334838, "PEGINTRON": 1.2010953968307692, "PREGABALIN": 1.0019424231648584, "RISPERIDONE": 2.661810997863701, "SIFROL": 3.1143873074312083, "SUBOXONE": 2.211182242728886, "TAMIFLU": 1.1439632891417442, "TOVIAZ": 3.975150120917871, "TOZINAMERAN": 1.3610826042144126, "TRELEGY": 1.4141760047908678, "VIAGRA": 1.9691825599523305, "VIMPAT": 1.8914976684838796, "XELJANZ": 1.4015149439536658, "XTANDI": 1.022422098276909, "ZYPADHERA": 1.441306467775155, "ZYPREXA": 2.1677128202902334, "null": 1.8717121286679144}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5194.json
index 7bf5cbc9b63..6a412f3c8d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5194.json
@@ -1 +1 @@
-{"ADCIRCA": 2.539406521659177, "ALIMTA": 1.029958565380712, "ANTIBIOTICS": 16.5333227963875, "ARIPIPRAZOLE": 1.504809485292537, "ASPARAGINASE": 2.221652374359274, "BENZODIAZEPINES": 28.02188055093436, "BEVACIZUMAB": 3.035248812880296, "BIKTARVY": 4.74743931081544, "BUPIVACAINE": 6.940268523046822, "BUSULFAN": 1.0232220726841696, "BYETTA": 1.2321774324018608, "CHAMPIX": 1.2408958036068714, "CICLOSPORIN": 1.9515772827988025, "COMBIVIR": 1.2336242913422146, "CUBICIN": 3.617554071226496, "CYMBALTA": 1.4904889533524703, "CYTARABINE": 1.8383813324525515, "DEXAMETHASONE": 1.5655389739446623, "DOLUTEGRAVIR": 5.956877568247251, "DULOXETINE": 3.4676443170201927, "EMPAGLIFLOZIN": 2.4093129759983527, "ENOXAPARIN": 1.8737536300876991, "ESOMEPRAZOLE": 1.981114275915145, "EXJADE": 3.559153564554105, "FENTANYL": 3.38568436795332, "FYCOMPA": 2.8803371331903262, "GLUCAGON": 16.45119628948413, "HARVONI": 1.3317767306177888, "IBUPROFEN": 2.602545099966308, "JANUMET": 1.0776810803388135, "JANUVIA": 1.4163298029722375, "KEPPRA": 2.238745380779076, "KYMRIAH": 5.526766816122155, "LACOSAMIDE": 2.0492778987998506, "LATUDA": 1.059515655733, "LEVETIRACETAM": 4.058162025087208, "LEVOFLOXACIN": 1.5661765482780896, "LYRICA": 1.324521358305645, "MEKINIST": 1.3889263524548143, "MEMANTINE": 7.662391456502933, "MIDAZOLAM": 2.465309056845878, "NALOXONE": 25.83439398790766, "NEULASTA": 1.656641420719187, "NOT": 1.838959649676918, "NPLATE": 1.3992529155946336, "OLANZAPINE": 5.563457302871587, "ONCASPAR": 4.106175822646401, "OPSUMIT": 1.8671834459648924, "OPTIMARK": 30.643123341667888, "OXYBUTYNIN": 5.412152830409378, "PALIPERIDONE": 14.321456635387635, "PANTOPRAZOLE": 1.267903658198841, "PEGASYS": 1.3529019433641822, "PEGINTRON": 3.210409064732784, "PLAVIX": 1.2115925163316097, "POSACONAZOLE": 6.86516154137159, "PRIALT": 19.506438340585365, "REVLIMID": 2.460071258065713, "RIBAVIRIN": 2.2090090052939235, "RISPERIDONE": 4.162468380293945, "RIVASTIGMINE": 45.407689271142, "SOLIRIS": 1.705063546661855, "SUBOXONE": 1.4697050880133506, "TACROLIMUS": 4.740266931794532, "TAMIFLU": 1.313877068708196, "TIGECYCLINE": 13.065675539197924, "TRACLEER": 1.6010518048295723, "VELTASSA": 2.292959871453379, "VORICONAZOLE": 1.896381440431602, "VOTRIENT": 1.0057929085043085, "XTANDI": 1.1744686407106522, "YESCARTA": 8.193608969219776, "ZYPREXA": 2.4106202658282565, "null": 1.8040700094617472}
\ No newline at end of file
+{"COMIRNATY": 0.4632325615181797, "CYMBALTA": 9.199687047576406, "GARDASIL": 16.407748403799914, "SPIKEVAX": 0.2584460150991811, "TOZINAMERAN": 0.865188120216561, "VAXZEVRIA": 0.1593706740490593, "null": 2.043715201362551}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5195.json
index cfd704a6844..47c7bf06b18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5195.json
@@ -1 +1 @@
-{"FENTANYL": 183.23582245372936}
\ No newline at end of file
+{"HUMALOG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5196.json
index 6938e19e00b..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5196.json
@@ -1 +1 @@
-{"null": 3.826423134070761}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5197.json
index d87fe5d02d6..f2c405301ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5197.json
@@ -1 +1 @@
-{"VAXZEVRIA": 1.4029166083137423}
\ No newline at end of file
+{"ABACAVIR": 3.383961996854826, "ATRIPLA": 4.516914326705232, "BUSULFAN": 7.051163571251954, "EMTRICITABINE": 38.58930676135778, "EXJADE": 15.03759326325902, "FORXIGA": 45.79477279449783, "HEPSERA": 47.59055984878525, "JARDIANCE": 25.42509783038011, "KALETRA": 7.480753479581756, "LOPINAVIR": 35.848356057355105, "NORVIR": 13.658677211931511, "TENOFOVIR": 208.0560519742387, "TRUVADA": 5.991290921759968, "VIREAD": 46.00087635976696, "ZYPREXA": 11.715524148597604, "null": 0.5050172765683136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5198.json
index 4b351c03d1b..b81c957f633 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5198.json
@@ -1 +1 @@
-{"null": 2.526902834298863}
\ No newline at end of file
+{"JARDIANCE": 26.475117487031376, "null": 0.4064585265653785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5199.json
index 20020f8a1a6..c17cdad854f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5199.json
@@ -1 +1 @@
-{"null": 1.115179498463266}
\ No newline at end of file
+{"BYDUREON": 6.255026771649692, "FORXIGA": 15.02345359389014, "HUMALOG": 9.74944499130071, "INSULIN": 8.598739531160085, "JANUMET": 24.98125515192253, "JANUVIA": 15.958974386412882, "JARDIANCE": 35.0095859800841, "LANTUS": 19.27820567004624, "LEVEMIR": 18.287012638590863, "NOVORAPID": 10.465314744157077, "TOUJEO": 26.25361228980562, "TRULICITY": 14.252844878612102, "VICTOZA": 22.176803919062717, "null": 0.4139994627506805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/52.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/52.json
index 7d3d1269166..2ebc2296945 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/52.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/52.json
@@ -1 +1 @@
-{"null": 1.431887213883862}
\ No newline at end of file
+{"ABILIFY": 3.673334873313861, "AERIUS": 3.016131981903649, "AFINITOR": 0.3430768752312603, "AMINOSALICYLIC": 0.4689796344307103, "ANTIBIOTICS": 7.656193957164304, "APIDRA": 0.365502911917363, "ARIPIPRAZOLE": 4.064001302398715, "ATRIPLA": 0.0415615211522213, "AZILECT": 4.430084591115952, "BENLYSTA": 0.5300116120620074, "BORTEZOMIB": 3.433742445346988, "BRINTELLIX": 1.0346778652923547, "BRIVARACETAM": 16.6327666826383, "BRIVIACT": 4.2286544214840704, "BUMETANIDE": 6.596792511968096, "BUPIVACAINE": 3.058253986678419, "BUPRENORPHINE": 1.8767940805810377, "CARBIDOPA": 3.6096053274572095, "CHAMPIX": 12.905389238812257, "CICLOSPORIN": 0.3539669138155968, "CLOPIDOGREL": 0.1947882154077297, "COMBIVIR": 1.0432628919256517, "COMIRNATY": 0.0497417604036305, "COMTAN": 7.507020106136249, "CYMBALTA": 2.5785133784533807, "DEXAMETHASONE": 0.5983240950778879, "DULOXETINE": 2.334526815687807, "ELIQUIS": 0.2497085522877366, "EPIDYOLEX": 15.059179866566067, "FENTANYL": 1.635488334509277, "FYCOMPA": 6.167782667245704, "GARDASIL": 0.9266735234805448, "HUMALOG": 0.3992340493637483, "HYDROCORTISONE": 0.8296750354630532, "IBUPROFEN": 0.8883228637192127, "INFANRIX": 2.6070964307545883, "INSULIN": 0.3712434227169071, "IRBESARTAN": 1.882761072022387, "JANUMET": 0.3360919107442385, "JARDIANCE": 0.2548298629208828, "KAFTRIO": 2.142837896252696, "KALETRA": 0.6731982282769753, "KEPPRA": 5.756936452959672, "KEYTRUDA": 0.1191276782498072, "LANTUS": 0.6660845769197875, "LATUDA": 7.180708771614565, "LEVETIRACETAM": 6.499697901118006, "LEVODOPA": 3.506483117110069, "LEVOFLOXACIN": 0.6212849086199738, "LURASIDONE": 15.157694377695112, "LYRICA": 2.3044147632241634, "MEMANTINE": 7.068974726541299, "MICARDIS": 0.6542269987398716, "MIDAZOLAM": 2.1346029689101007, "MMRVAXPRO": 1.84008611476073, "NEXAVAR": 0.168666320608838, "NIMENRIX": 1.4833514539414658, "OLANZAPINE": 5.2414653370770194, "OXYBUTYNIN": 3.974543768811076, "PEGASYS": 0.5097525584999308, "PEGINTRON": 1.4386580562090516, "PLAVIX": 0.2700911954501455, "PREGABALIN": 1.300472466083365, "PREVENAR": 2.028533872098258, "RIBAVIRIN": 0.8808818666439223, "RISPERIDONE": 7.068079384800062, "ROTATEQ": 0.6441515973442749, "SIFROL": 5.513847270309444, "SILDENAFIL": 1.2538233159131065, "SPIKEVAX": 0.1045368384511007, "STALEVO": 3.405736030382148, "SUBOXONE": 2.261691333626838, "SUTENT": 0.1923055002845214, "TAMIFLU": 114.07796883334296, "TOZINAMERAN": 0.1639380816646331, "VAXZEVRIA": 0.040399458612376, "VFEND": 1.4722529716014197, "VIAGRA": 0.7795230707914629, "VIMPAT": 4.281961212219553, "XOLAIR": 0.3570399522859986, "XTANDI": 0.3855273078315759, "XYREM": 2.562222455144273, "ZONISAMIDE": 10.15880150495769, "ZYPADHERA": 4.974195543518177, "ZYPREXA": 3.566399861795604, "null": 2.177992589195754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/520.json
index 56a4c7730a9..c0e76dafd48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/520.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/520.json
@@ -1 +1 @@
-{"CUBICIN": 2551.583420968558, "DAPTOMYCIN": 1146.818714423247}
\ No newline at end of file
+{"null": 2.282700417918916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5200.json
index 15588da709c..5f714aef723 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5200.json
@@ -1 +1 @@
-{"GARDASIL": 12.166718115190466}
\ No newline at end of file
+{"FORXIGA": 18.0952202899212, "HUMALOG": 6.057966491246829, "INSULIN": 17.145558602460984, "JANUVIA": 15.163698231122646, "JARDIANCE": 30.196644897764397, "LANTUS": 9.098572941901336, "LEVEMIR": 16.061201896992877, "TRULICITY": 20.174378131012823, "VICTOZA": 18.197696159033992, "null": 0.4079432432034038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5201.json
index 2873665a1a5..d2922f8180d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5201.json
@@ -1 +1 @@
-{"ADENURIC": 46.56288698766726, "COMIRNATY": 1.1263328665094698, "COVID19": 1.6976419817667328, "NEXAVAR": 2.9009174589856137, "NOVOSEVEN": 48.53319812038328, "PEGASYS": 1.967306058230887, "TESTOSTERONE": 50.04406637958645, "VAXZEVRIA": 2.391820014825808}
\ No newline at end of file
+{"ABASAGLAR": 46.47747577782364, "ACTOS": 10.487066583468224, "ACTRAPID": 10.672403628470969, "AFINITOR": 1.3721969988931977, "APIDRA": 18.33535461941884, "ARANESP": 1.1962080434344564, "ARAVA": 0.2123992219696975, "AVANDIA": 0.7203074037223725, "BIKTARVY": 4.106038528650144, "BYDUREON": 13.68815061833364, "BYETTA": 11.171252323411396, "CANAGLIFLOZIN": 16.67157348414034, "CHAMPIX": 0.5663619838359378, "CICLOSPORIN": 0.3991376906638106, "CLOPIDOGREL": 0.4476705454664546, "COMIRNATY": 0.0549926169382652, "CYMBALTA": 0.5634826202013783, "DAPAGLIFLOZIN": 6.146722992521417, "DULAGLUTIDE": 44.57301064512043, "ELIQUIS": 0.3307761875039888, "EMPAGLIFLOZIN": 7.112116025254086, "ENBREL": 0.4522681205597371, "ENTRESTO": 1.2581643810214655, "EUCREAS": 20.25568493182673, "EXFORGE": 3.5103486248965994, "FIASP": 7.969175260571077, "FORXIGA": 12.578866016411542, "GALVUS": 13.781345171413143, "GLIBENCLAMIDE": 10.995062700252134, "HUMALOG": 30.89803240118812, "IBRANCE": 0.1534988639965633, "ICANDRA": 35.549503557834065, "INSULATARD": 5.99950847690032, "INSULIN": 26.80602783002848, "INVOKANA": 5.355835441293127, "ISOPHANE": 31.151325040449557, "JANUMET": 5.541774702632454, "JANUVIA": 6.906844466064206, "JARDIANCE": 12.315057084845938, "KEYTRUDA": 0.2617825355971037, "LANTUS": 22.414038697485747, "LATUDA": 1.6589103592600376, "LEVEMIR": 18.86236890446116, "LIPROLOG": 22.876231371127083, "LIRAGLUTIDE": 13.009536707015313, "LYRICA": 0.8706699046738959, "LYUMJEV": 23.480798525429787, "METFORMIN": 29.01814730792279, "MIXTARD": 6.568116180033895, "NOVONORM": 14.670057517393955, "NOVORAPID": 8.751384351868246, "OLANZAPINE": 0.6391516897250428, "ONGLYZA": 8.674524125061561, "OPTISULIN": 126.52260579786405, "OZEMPIC": 8.694542836589525, "PASIREOTIDE": 17.48409997184417, "RASILEZ": 4.017675890279441, "REPAGLINIDE": 10.050717719234516, "RIVAROXABAN": 5.167941820910829, "RYBELSUS": 24.09881812677861, "SIGNIFOR": 27.43364251437124, "SOMATROPIN": 3.522666981774041, "SPIKEVAX": 0.0304764541430571, "SUTENT": 0.1482531780891037, "TASIGNA": 1.348726905452203, "TOUJEO": 29.2511753821142, "TOZINAMERAN": 0.1147173834908561, "TRESIBA": 8.823848630402999, "TRULICITY": 28.468341355961996, "VAXZEVRIA": 0.0074055078786745, "VIAGRA": 0.6143427820358837, "VICTOZA": 11.67264215075313, "VILDAGLIPTIN": 9.115781457933426, "XELJANZ": 0.2599048894519531, "ZOSTAVAX": 0.4254698179352167, "ZYPREXA": 0.749632224275681, "null": 0.5732356909888033}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5202.json
index f9f32714b06..0d3a16adfcc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5202.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 33.10717474191843, "ELIQUIS": 12.511508345070762}
\ No newline at end of file
+{"ALEMTUZUMAB": 5.43219458563702, "ARAVA": 1.544765519481455, "ATAZANAVIR": 7.945945091322272, "BYDUREON": 2.8404908706096053, "BYETTA": 31.809221402745628, "CICLOSPORIN": 0.8948854981994381, "COMIRNATY": 0.6094158669739433, "ENBREL": 2.961113723684197, "FORSTEO": 1.2391923420203736, "GARDASIL": 1.028439408444723, "HUMALOG": 0.696810837602233, "IRBESARTAN": 10.528454952190708, "JANUMET": 3.262181597761555, "JANUVIA": 2.034800700527514, "LEMTRADA": 8.872073549853997, "NUCALA": 3.522080705592737, "PEGASYS": 1.888216344274242, "PEGINTRON": 3.4144234193954053, "SOMAVERT": 97.82226335142823, "SPIKEVAX": 0.3152653164292582, "SUTENT": 0.4899325686868513, "TASIGNA": 2.5519496044010195, "TOZINAMERAN": 0.3989189381023596, "VAXZEVRIA": 0.2471136076955749, "VICTOZA": 8.500968997216617, "XELJANZ": 0.6774736261815256, "ZOSTAVAX": 4.380189515598813, "null": 1.2907119733361012}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5203.json
index 03b778baaf1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5203.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5204.json
index d817e8daa87..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5204.json
@@ -1 +1 @@
-{"ACTOS": 2.613109270406352, "AERIUS": 1.8508785787118425, "AMIKACIN": 3.01167565933921, "APROVEL": 3.2007463843106434, "ATAZANAVIR": 1.0813547732601718, "BEDAQUILINE": 1.04766009737747, "BORTEZOMIB": 1.2760127286722391, "BUSULFAN": 1.0396574278473991, "BYETTA": 1.1748493576347718, "CANAGLIFLOZIN": 12.955663861865364, "CASPOFUNGIN": 1.7351755076356328, "CELECOXIB": 2.4527901017766607, "COAPROVEL": 3.7134303281364462, "DAPAGLIFLOZIN": 15.461530444811292, "DARUNAVIR": 2.463018969322534, "DELAMANID": 2.2356882101608258, "DEXAMETHASONE": 2.11532608318124, "DULOXETINE": 1.2392276888816338, "EFAVIRENZ": 1.6903508427466336, "EMPAGLIFLOZIN": 21.154526142699968, "EMTRICITABINE": 5.552220482419975, "ENTRESTO": 1.0107401553390691, "EPIVIR": 2.752790521771012, "ESOMEPRAZOLE": 47.04828479884403, "EUCREAS": 12.854079728363898, "EVEROLIMUS": 1.9969067137878551, "EXFORGE": 1.335081127794119, "EXJADE": 4.195162887286397, "EXVIERA": 2.8869399621863963, "FENTANYL": 2.8832795303616634, "FORXIGA": 9.14700474709596, "GANCICLOVIR": 4.5232319866114725, "GLIBENCLAMIDE": 5.124426232136686, "GLUCAGON": 5.638466002694288, "HEPSERA": 9.569751333342657, "HYDROCORTISONE": 2.072632917201095, "IBUPROFEN": 8.926399798142526, "INSULIN": 1.0129590211687225, "INVOKANA": 35.09673005468178, "IRBESARTAN": 3.1010784619048923, "IRINOTECAN": 1.427642173928751, "ISENTRESS": 3.129901270487822, "JANUMET": 4.441319586252592, "JANUVIA": 1.3917883791284753, "JARDIANCE": 9.694514896800808, "KALETRA": 1.9133051900635776, "KEPPRA": 1.2366179568621276, "KYMRIAH": 1.6713859106720148, "LACOSAMIDE": 3.252722006761424, "LAMIVUDINE": 5.42732983525791, "LEVETIRACETAM": 2.5634366948375056, "LEVOFLOXACIN": 1.0828102662201218, "LOPINAVIR": 4.680288115825212, "MANNITOL": 7.857124829315548, "METFORMIN": 4.27529891119734, "MIDAZOLAM": 6.131424777076011, "MISOPROSTOL": 12.174774813714428, "NORVIR": 2.035549662981824, "OLANZAPINE": 1.6312822100821132, "PANTOPRAZOLE": 1.113297283924945, "PREGABALIN": 1.5829836238050363, "PROPRANOLOL": 2.14146044815562, "RASILEZ": 1.8866234096652847, "REPAGLINIDE": 11.586812331360129, "RISPERIDONE": 2.7703926846867457, "ROTATEQ": 2.374378329602276, "SILDENAFIL": 1.3651361917612983, "SPINRAZA": 1.454391888426489, "SPIRONOLACTONE": 8.104403705802996, "TENOFOVIR": 15.265377300721712, "TRACLEER": 1.223797553109092, "VALSARTAN": 2.0510917774333177, "VELMETIA": 14.374027664108525, "VELTASSA": 4.637132775526004, "VILDAGLIPTIN": 8.964177702938553, "VIREAD": 3.2378047216976333, "null": 2.862740252099892}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5205.json
index 141a76e6617..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5205.json
@@ -1 +1 @@
-{"CELECOXIB": 24.363058398203624, "FORXIGA": 6.216469818177934, "null": 5.491948514937654}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5206.json
index b818de5d266..5727b2d19a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5206.json
@@ -1 +1 @@
-{"ABACAVIR": 1.5905168453656526, "ABILIFY": 83.15517160287843, "ARIPIPRAZOLE": 9.3886624329378, "BIKTARVY": 24.792700553421984, "INSULIN": 5.647429494658617, "JANUMET": 2.137132623247167, "KEPPRA": 3.073114908022468, "OLANZAPINE": 6.069100583928666, "PEGASYS": 1.2709871489205211, "PREGABALIN": 4.542569620838044, "ZYPREXA": 10.252153690012651}
\ No newline at end of file
+{"BIKTARVY": 111.74457758253568, "null": 0.5049055256884603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5207.json
index 1cf64b10383..f9503686d68 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5207.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.936384023580917, "INVOKANA": 54.81103034817952, "JARDIANCE": 1.6353729031493458, "KEPPRA": 2.760233712987468, "LEVETIRACETAM": 6.244520019860818, "ZOSTAVAX": 1.719012186140483, "null": 2.19872340019254}
\ No newline at end of file
+{"LEMTRADA": 162.12141247352884, "null": 0.2709068880680003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5208.json
index ce5c0e4230b..a87b733ed5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5208.json
@@ -1 +1 @@
-{"SPIKEVAX": 38.15829329414724}
\ No newline at end of file
+{"ADALIMUMAB": 0.1301056447356038, "ADENURIC": 45.28957475717383, "AFINITOR": 0.988709083896281, "ALENDRONATE": 93.34742101821249, "APIXABAN": 6.940674305772917, "ARANESP": 1.5740323841249493, "ARAVA": 0.3292692221858233, "ATRIPLA": 1.1424822275252, "BOSULIF": 2.087145251971984, "BRILIQUE": 11.203176638513517, "BUDESONIDE": 0.3780251694403966, "BUMETANIDE": 5.032878512166839, "BYDUREON": 2.1341221704579683, "BYETTA": 3.015934234049155, "CELLCEPT": 1.1620913127325203, "CICLOSPORIN": 1.326160322894647, "CIMZIA": 0.2962019717882873, "CLOPIDOGREL": 0.7553683845449747, "COAPROVEL": 2.6818607273557, "COMIRNATY": 0.3031777662111585, "COSENTYX": 0.5383932991562239, "CYMBALTA": 0.3323734924285249, "ELIQUIS": 2.4263799207975025, "ENBREL": 0.4645524240750644, "ENTRESTO": 4.925266766803385, "EXFORGE": 3.8660730656265248, "EXJADE": 0.7765488389287776, "FASLODEX": 1.0772232809498852, "FEBUXOSTAT": 90.03909919508094, "FORSTEO": 1.2454125339062605, "FORXIGA": 1.5008364979999775, "HUMALOG": 1.54350997706693, "HUMIRA": 0.921353814050299, "IBRANCE": 0.4460525826591223, "IBUPROFEN": 1.1490796320405037, "INLYTA": 1.512344886489528, "IRBESARTAN": 2.188177064547534, "JAKAVI": 1.8664594091713855, "JANUMET": 3.858260003809165, "JANUVIA": 3.208445921147673, "JARDIANCE": 1.6271482815573302, "LANTUS": 0.8716411383762224, "LEVEMIR": 1.177052120689792, "LYRICA": 0.6968456484210334, "MEPOLIZUMAB": 1.233753328176183, "MICARDIS": 2.125469223018796, "NEXAVAR": 0.3402325376050515, "OLANZAPINE": 0.3580539547678968, "OMALIZUMAB": 0.8492064899514475, "OPSUMIT": 1.9144189734490795, "PEGASYS": 0.9353917875759948, "PEGINTRON": 0.400136324359485, "PLAVIX": 1.0843990831912582, "REVATIO": 7.449146845248789, "RITUXIMAB": 0.798158143059588, "SIMPONI": 0.3585599935597227, "SPIKEVAX": 0.4684215894319367, "STELARA": 1.1164833217259096, "SUTENT": 2.2146413621083147, "TASIGNA": 1.2708867622453062, "TICAGRELOR": 5.717688853474336, "TOZINAMERAN": 0.7669746271290583, "TRACLEER": 1.2213705694060315, "TREMFYA": 2.410526970313048, "TRUVADA": 0.5271660714562465, "VAXZEVRIA": 0.4681621820301048, "VELTASSA": 3.912958067469365, "VIAGRA": 0.6975803781931998, "XELJANZ": 1.5006746417051262, "XOLAIR": 0.4643132740111335, "XTANDI": 1.6032488431495076, "ZOSTAVAX": 6.056136393468823, "ZYPREXA": 0.3874053358221035, "null": 1.1811231417706716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5209.json
index 2dd0e79304a..68e83787edd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5209.json
@@ -1 +1 @@
-{"SPIKEVAX": 11.364666689149423}
\ No newline at end of file
+{"CLOPIDOGREL": 5.889421773352323, "COMIRNATY": 0.2405385542403609, "null": 1.3787307955646513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/521.json
index c97db9944e4..54ce361be21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/521.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/521.json
@@ -1 +1 @@
-{"null": 1.0688549701826997}
\ No newline at end of file
+{"null": 4.29790114419221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5210.json
index 682411bd4d8..0e15d0ad6c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5210.json
@@ -1 +1 @@
-{"ETANERCEPT": 135.73418500554973, "JARDIANCE": 6.7273094002582825, "LATUDA": 20.2521963370098, "SIMPONI": 9.661356747326696, "STELARA": 9.414893098362, "ZOSTAVAX": 5.5518264464461}
\ No newline at end of file
+{"CICLOSPORIN": 24.091540229914287, "null": 0.8299178612331063}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5211.json
index 7bce6651dfb..bcf3c953f48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5211.json
@@ -1 +1 @@
-{"ABILIFY": 29.55024842669443, "ARIPIPRAZOLE": 8.848245356332344, "INSULIN": 8.453228637314536, "OLANZAPINE": 34.31149637455153, "ZYPREXA": 45.67785530482576}
\ No newline at end of file
+{"MACI": 69022.96824143936, "null": 0.2252411949115869}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5212.json
index e7fb165591c..ddb365cd57b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5212.json
@@ -1 +1 @@
-{"ALLI": 1080.051204159216, "CANNABIDIOL": 132.0096209278199, "GARDASIL": 21.41090238761431, "ROTASHIELD": 1116.1260303304462, "null": 2.3190259513510965}
\ No newline at end of file
+{"null": 1.2825404106852534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5213.json
index 9bd0d953f1d..c8a7cdce7cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5213.json
@@ -1 +1 @@
-{"BEOVU": 33.85487800279317, "EYLEA": 74.88310403194838, "JETREA": 562.3379355361022, "LANTUS": 1.4896180889698585, "TOZINAMERAN": 2.2876058947560405, "VIAGRA": 5.967008577651318}
\ No newline at end of file
+{"ALEMTUZUMAB": 66.10240486558885, "CICLOSPORIN": 60.89858667148621, "NEXOBRID": 3295.829608504337, "SOLIRIS": 50.34185270030078, "null": 0.193623808759578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5214.json
index 906ff5503d8..ebcc0430d60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5214.json
@@ -1 +1 @@
-{"null": 4.007036161400551}
\ No newline at end of file
+{"null": 0.5639274422831586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5215.json
index df18bed8a12..65eb06d1ec8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5215.json
@@ -1 +1 @@
-{"null": 1.015699803528595}
\ No newline at end of file
+{"ABATACEPT": 0.5343714524366859, "ALEMTUZUMAB": 39.745373946787936, "ASPARAGINASE": 8.361455674225297, "AZACITIDINE": 7.677888281745559, "AZATHIOPRINE": 6.006840865693885, "BASILIXIMAB": 19.152850863362566, "BLINATUMOMAB": 18.058109803042903, "BORTEZOMIB": 6.88856001544937, "BUDESONIDE": 2.407666985102093, "BUSILVEX": 23.23780984134875, "BUSULFAN": 137.89242214332782, "CANCIDAS": 7.090237349909074, "CARMUSTINE": 19.98814560118569, "CASPOFUNGIN": 7.052988596759614, "CELLCEPT": 7.402579540290782, "CICLOSPORIN": 74.62545185890804, "CYTARABINE": 5.862931451392072, "DEFITELIO": 72.64573373980406, "DEXAMETHASONE": 1.1122792924821612, "EMEND": 10.95782757742808, "EXJADE": 5.228228663555145, "FILGRASTIM": 14.274505669524556, "GANCICLOVIR": 25.46792910769731, "ICLUSIG": 14.359605768883863, "JAKAVI": 8.898408166039426, "KEYTRUDA": 0.42513433835888, "KYMRIAH": 3.204861424632776, "METHOTREXATE": 4.563150150240687, "MYCOPHENOLATE": 15.416641353226195, "NEXAVAR": 0.9284630481202046, "NOXAFIL": 30.741090940429768, "POSACONAZOLE": 16.864822357495758, "RAPAMUNE": 14.82187447314644, "RITUXIMAB": 1.2467376465935354, "RUXOLITINIB": 7.164081477653011, "SOLIRIS": 9.746955301883135, "SPRYCEL": 4.341178167173663, "TACROLIMUS": 26.73033623851588, "TEPADINA": 383.9366784620941, "TOBRAMYCIN": 10.042811175242203, "VFEND": 5.906064883103782, "null": 0.554817381476319}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5216.json
index 62f54426ac0..02e2b0b2f8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5216.json
@@ -1 +1 @@
-{"BORTEZOMIB": 102.2879728018637, "BUSULFAN": 30.61399722634533, "CICLOSPORIN": 12.700526944892667, "CRIZOTINIB": 604.1764313162163, "SPINRAZA": 58.59525912964613, "SYNAGIS": 85.09869161671082}
\ No newline at end of file
+{"CICLOSPORIN": 56.74841693793063}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5217.json
index fda11347e62..d7cd56ec87e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5217.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5217.json
@@ -1 +1 @@
-{"BYETTA": 17.248697992406434, "JANUMET": 18.26661707233712, "NEXAVAR": 25.96536125872216, "STIVARGA": 24.28542944959026}
\ No newline at end of file
+{"ADALIMUMAB": 0.7331382678371344, "ALEMTUZUMAB": 32.47365204494937, "AZATHIOPRINE": 7.322813583771836, "BASILIXIMAB": 82.80753994802072, "BORTEZOMIB": 12.998549725714092, "BUDESONIDE": 12.763184582639123, "BUSULFAN": 86.1526663733048, "CANCIDAS": 37.73632313185117, "CELLCEPT": 4.47633719783671, "CICLOSPORIN": 93.9378934515538, "CIDOFOVIR": 145.9283893197127, "CYTARABINE": 14.277123102281712, "GANCICLOVIR": 19.20732665701491, "ICLUSIG": 12.296544679845432, "JAKAVI": 4.946653998405916, "METHOTREXATE": 4.446861579183851, "MYCOPHENOLATE": 33.62392949366133, "NOXAFIL": 20.70373000431945, "SOLIRIS": 3.329436792457472, "TACROLIMUS": 27.46189931928016, "THIOTEPA": 177.81909816834084, "null": 0.2068639276062199}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5218.json
index 9267ea2b592..5640503bcbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5218.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5218.json
@@ -1 +1 @@
-{"AFINITOR": 16.67909751977598, "BYETTA": 10.333741608504498, "CABOMETYX": 12.398751952132695, "FASLODEX": 7.959810491734183, "JANUMET": 8.672430433070476, "JANUVIA": 13.121399701689672, "MEKINIST": 14.589020435136348, "NEXAVAR": 43.63209954533655, "PEMBROLIZUMAB": 16.600920758504564, "SORAFENIB": 69.905760963194, "STIVARGA": 14.871516198932746, "VOTRIENT": 11.730257387447825}
\ No newline at end of file
+{"BUDESONIDE": 10.779260772207216, "BUSULFAN": 44.585717975201376, "CICLOSPORIN": 91.90011788629268, "null": 0.2386824126027056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5219.json
index e8128498935..50532704f93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5219.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5219.json
@@ -1 +1 @@
-{"ABEMACICLIB": 81.60225083279639, "ABRAXANE": 67.35189139787303, "AFINITOR": 29.473717364568763, "ALIMTA": 1.382691488590421, "ALPELISIB": 86.4907984598958, "AVASTIN": 4.2378201426009, "BEVACIZUMAB": 7.602820045694378, "BYETTA": 1.7221823267092855, "CABAZITAXEL": 76.68625987070743, "CABOMETYX": 16.261267148832726, "CAELYX": 3.441742769172808, "CAPECITABINE": 37.54396653800693, "CELECOXIB": 1.8756022327230248, "DABRAFENIB": 10.48483944623639, "DENOSUMAB": 63.03282663313394, "DEXAMETHASONE": 2.3885674742849763, "DOCETAXEL": 18.209331432456565, "ENZALUTAMIDE": 21.176231017645318, "ERIBULIN": 25.38961047309413, "ERLEADA": 13.247050129787748, "EVEROLIMUS": 44.916092013069736, "FASLODEX": 58.59786894763333, "FORSTEO": 1.6836412632215687, "FULVESTRANT": 78.41901248631949, "GEFITINIB": 35.13422829398389, "GLIVEC": 3.703569971895906, "HERCEPTIN": 8.710863335773325, "IBRANCE": 3.5405607850667407, "IPILIMUMAB": 1.7365293471733652, "IRESSA": 24.143152079819867, "IRINOTECAN": 5.865332170718887, "JANUMET": 2.1760633339579263, "JANUVIA": 2.559705449641625, "JEVTANA": 10.591024199035726, "KISQALI": 37.6961749525868, "KYMRIAH": 1.9708181309324615, "LYNPARZA": 7.859001519196086, "MEKINIST": 9.656950559939787, "METHOTREXATE": 1.0688311178629235, "NEULASTA": 2.0120600764763124, "NEXAVAR": 9.928395767594251, "NUBEQA": 28.788696981352857, "OLAPARIB": 14.81828111570877, "OPDIVO": 3.940960003961727, "OSIMERTINIB": 19.71399934239578, "PACLITAXEL": 13.182002823954797, "PAZOPANIB": 12.616916336947613, "PEMBROLIZUMAB": 1.4382744636665308, "PEMETREXED": 3.4453514551195266, "PLUVICTO": 24.338396053255607, "RIBAVIRIN": 1.0304666920630992, "RIBOCICLIB": 77.19685287946722, "SORAFENIB": 8.459648334480317, "STIVARGA": 4.69540707373648, "TAGRISSO": 16.023886140613364, "TRODELVY": 4.608094214969409, "VOTRIENT": 6.969653136969008, "XGEVA": 23.43139547256248, "XOFIGO": 106.22421418528654, "XTANDI": 9.678539324149195, "ZOLEDRONIC": 29.374429379307216, "ZOMETA": 20.61406513089984}
\ No newline at end of file
+{"BUSULFAN": 106.08091308428784, "CELLCEPT": 16.701262780160683, "CICLOSPORIN": 48.41314782017566, "null": 0.3012579467041654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/522.json
index 5078c4cd0c4..a6b3edc4b27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/522.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/522.json
@@ -1 +1 @@
-{"NUCALA": 90.51391258008884}
\ No newline at end of file
+{"CICLOSPORIN": 6.956140472839916, "GARDASIL": 4.142644689710695, "SUBOXONE": 11.132558882060517, "null": 1.7979172557530176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5220.json
index 68e2198ad6a..7087cab3ff9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5220.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5220.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 31.53780885532417, "BLINATUMOMAB": 317.92045073071745, "FASLODEX": 21.75721366115137, "MEKINIST": 22.585871291859128, "XOFIGO": 112.18539757329346}
\ No newline at end of file
+{"ALEMTUZUMAB": 76.73224056918353, "AZACITIDINE": 13.551880321876038, "AZATHIOPRINE": 7.592747026790454, "BASILIXIMAB": 61.14477896990847, "BUDESONIDE": 10.1239218380943, "BUSULFAN": 139.27196764486726, "CELLCEPT": 3.4346999175371637, "CICLOSPORIN": 88.88632025626295, "CYTARABINE": 9.656865195379297, "ICLUSIG": 27.43963679183444, "JAKAVI": 6.313849346398749, "MELPHALAN": 37.25819953393263, "METHOTREXATE": 4.511363050164665, "MYCOPHENOLATE": 35.86845437186013, "THIOTEPA": 66.86096760754364, "null": 0.2041045304106711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5221.json
index c1c99191a6a..f799729472b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5221.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5221.json
@@ -1 +1 @@
-{"FASLODEX": 42.92133690505344, "FULVESTRANT": 129.858097469737}
\ No newline at end of file
+{"null": 0.7267193828409113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5222.json
index ef59cbcb317..f1b288d179e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5222.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5222.json
@@ -1 +1 @@
-{"ABRAXANE": 13.197444504172031, "AFATINIB": 54.04114445315533, "AFINITOR": 16.832961994307073, "ALECTINIB": 68.3430419709596, "ALIMTA": 2.985369263592658, "ALPELISIB": 24.052704377612688, "AVASTIN": 5.874240879541268, "BEVACIZUMAB": 8.111974753966239, "BRAFTOVI": 2.738881113488303, "CABOMETYX": 9.843372525467856, "CAPECITABINE": 23.31138394386436, "COBIMETINIB": 20.20165330636985, "COTELLIC": 16.145387217005425, "DABRAFENIB": 74.25310461855811, "DENOSUMAB": 6.587491386229211, "DEXAMETHASONE": 1.2051836957310098, "DOCETAXEL": 9.551172068634004, "ERIBULIN": 29.157739427233377, "EVEROLIMUS": 5.909263629848896, "FASLODEX": 8.379646929456335, "FULVESTRANT": 10.43434985679579, "GEFITINIB": 137.6437376626633, "HALAVEN": 6.281793230317255, "HERCEPTIN": 29.56260290571279, "IPILIMUMAB": 17.19086188377956, "IRESSA": 80.0331746628135, "IRINOTECAN": 5.109625320999466, "JANUMET": 1.7199332845916222, "KEYTRUDA": 1.4826664050908096, "KISQALI": 6.32742206755942, "KYMRIAH": 2.8065009163255565, "LONSURF": 2.7283763054667407, "LYNPARZA": 15.617552643685949, "MEKINIST": 82.53499261484295, "NEULASTA": 3.3168553549386783, "NEXAVAR": 4.810446488160231, "NPLATE": 2.2319180727125825, "OLAPARIB": 13.157402366366735, "OPDIVO": 13.022718873683932, "OSIMERTINIB": 67.20668007534422, "PACLITAXEL": 8.477027558357051, "PAZOPANIB": 17.219248089598665, "PEMBROLIZUMAB": 2.048016328557937, "PEMETREXED": 6.874710134936829, "PERJETA": 10.500135282061494, "PERTUZUMAB": 16.292755740890993, "RIBOCICLIB": 6.822928870819823, "RUBRACA": 9.00918446382834, "STIVARGA": 10.325037494890625, "TAFINLAR": 35.97684734159338, "TAGRISSO": 50.12358179331599, "TRODELVY": 31.637125528548697, "VEMURAFENIB": 27.65001307014291, "VIAGRA": 1.369335210284815, "VOTRIENT": 13.856136011628116, "XOFIGO": 13.794139072933582, "XTANDI": 2.042302060067424, "YERVOY": 44.140995296166736, "ZELBORAF": 38.98943047378976}
\ No newline at end of file
+{"OLANZAPINE": 19.549015445914836, "PANTOPRAZOLE": 56.51229843683184, "null": 2.145293937009585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5223.json
index 1e44b303fdd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5223.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5223.json
@@ -1 +1 @@
-{"AFINITOR": 48.23251351460835, "FULVESTRANT": 65.47261589686659}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5224.json
index 7bc66f51be2..19fd96117df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5224.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5224.json
@@ -1 +1 @@
-{"CAPECITABINE": 86.46264186745579, "FASLODEX": 43.02271515150407}
\ No newline at end of file
+{"AVASTIN": 12.41265986128413, "AZACITIDINE": 38.3197928802718, "BEVACIZUMAB": 7.378486904499383, "CAPECITABINE": 7.464779378129253, "CYTARABINE": 8.331078621858817, "DARZALEX": 11.924019192374526, "DOCETAXEL": 29.800393023951813, "DOXORUBICIN": 34.600772447016915, "ERBITUX": 83.49082057305466, "HERCEPTIN": 8.519913535980328, "IBRANCE": 2.099338082875037, "INTRONA": 33.74502690751007, "KEYTRUDA": 0.60518800437107, "MABTHERA": 37.55484819352679, "METHOTREXATE": 1.8780725987356572, "OLANZAPINE": 1.1565187865239344, "PACLITAXEL": 8.950975550845312, "PEGASYS": 7.660713173576283, "PLAVIX": 0.8954343752194232, "RITUXIMAB": 21.67473625431221, "TEGAFUR": 35.40515316876338, "XELODA": 20.84968282235198, "ZYPREXA": 1.1053757376666982, "null": 1.9801676598468287}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5225.json
index a27d801d8f6..498182855dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5225.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5225.json
@@ -1 +1 @@
-{"NEXAVAR": 17.7977981189221}
\ No newline at end of file
+{"null": 0.5506979862807917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5226.json
index e54f9e2391b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5226.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5226.json
@@ -1 +1 @@
-{"AFINITOR": 23.88215817212511, "EVEROLIMUS": 201.56682743457355, "MEKINIST": 23.562192365356974, "VOTRIENT": 25.069343267375142}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5227.json
index 23eaa8ca1be..3c58d0ff7a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5227.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5227.json
@@ -1 +1 @@
-{"ABEMACICLIB": 45.60456660337498, "ABRAXANE": 33.89317051002639, "AFINITOR": 37.86328708578322, "AFLIBERCEPT": 14.41295635305149, "ALPELISIB": 54.324832692377214, "ATEZOLIZUMAB": 6.005048548619468, "AVASTIN": 7.939289503185602, "BEVACIZUMAB": 21.05723344247512, "BYDUREON": 4.116329768710287, "BYETTA": 30.45572009179837, "CABAZITAXEL": 9.335836788883592, "CABOMETYX": 5.536644643945167, "CAELYX": 7.25386423540664, "CANNABIDIOL": 4.847550654733778, "CAPECITABINE": 35.235771579763714, "CELLCEPT": 1.0093315849696498, "CIALIS": 3.038713415793136, "CRIZOTINIB": 15.414354655152296, "DABRAFENIB": 13.449048807140931, "DENOSUMAB": 38.10326855860724, "DOCETAXEL": 13.095444590288958, "ERBITUX": 3.0853196008628085, "ERIBULIN": 35.45978175461751, "EVEROLIMUS": 49.40117682104076, "FASLODEX": 28.09298526523889, "FILGRASTIM": 2.8805693342087046, "FULVESTRANT": 52.18814367212594, "GEFITINIB": 24.86186010700512, "GLIVEC": 21.08590054413992, "HARVONI": 1.2704595820741575, "HERCEPTIN": 7.591623934907175, "IMATINIB": 27.180022868590324, "INFLIXIMAB": 3.302205441203484, "IPILIMUMAB": 2.2836365542458195, "IRESSA": 6.638260761547869, "IRINOTECAN": 15.964499057576887, "JAKAVI": 2.0871034853812107, "JANUMET": 19.86722797455172, "JANUVIA": 17.51079759940971, "JEVTANA": 3.2748000465265856, "KISQALI": 15.010978097019722, "KYMRIAH": 1.7912874635584306, "LONSURF": 2.0058006572712084, "LUTATHERA": 17.84323881092934, "LYNPARZA": 6.367899244213283, "MEKINIST": 8.854432934553861, "METFORMIN": 3.755512816027257, "METHOTREXATE": 1.4596098046142176, "NEULASTA": 1.7896483434801742, "NEXAVAR": 3.053413220496524, "OCTREOTIDE": 19.263468254725467, "OLAPARIB": 20.452640339256494, "OPDIVO": 3.0259874143756504, "OSIMERTINIB": 20.23584385119665, "PACLITAXEL": 8.32848896061637, "PANITUMUMAB": 18.687314237067422, "PANTOPRAZOLE": 1.694196614241524, "PAZOPANIB": 10.105666365323083, "PEMETREXED": 2.6483612872406144, "PIQRAY": 9.271530529835005, "RIBOCICLIB": 44.954693367645305, "ROACTEMRA": 1.2788956160599003, "RUBRACA": 1.4733335160972518, "SORAFENIB": 6.502514645388471, "STIVARGA": 23.874126517292257, "TAGRISSO": 7.575937267365127, "TRODELVY": 11.124902332275592, "VECTIBIX": 19.326109349843605, "VICTOZA": 2.166453664493657, "VOTRIENT": 6.395487341774149, "XELODA": 2.7565281006463964, "XOFIGO": 46.14883717192665, "XTANDI": 1.6980067701238728, "YERVOY": 3.2572757699936377, "ZOMETA": 5.033653834751213}
\ No newline at end of file
+{"null": 0.3066760465565514}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5228.json
index 7fbd6512668..0d0c193983d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5228.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5228.json
@@ -1 +1 @@
-{"ABEMACICLIB": 37.63510260335623, "ABRAXANE": 27.63412771485676, "AFINITOR": 23.47041266434797, "ALPELISIB": 23.682241113965883, "ATEZOLIZUMAB": 10.152256653265084, "AVASTIN": 9.557683838820886, "AXITINIB": 8.412810015504931, "BEVACIZUMAB": 17.951351519640106, "BYETTA": 12.670800529081014, "CABOMETYX": 16.957870119289613, "CAPECITABINE": 20.936748260534216, "CICLOSPORIN": 1.1920316897806809, "CYTARABINE": 1.2903836873857957, "DABRAFENIB": 26.540211495558733, "DENOSUMAB": 15.123245947783852, "DEXAMETHASONE": 1.1054155117318398, "DOCETAXEL": 15.80763441352502, "EVEROLIMUS": 41.68066664429985, "EXFORGE": 1.1904230531870688, "FASENRA": 1.1415677909854378, "FASLODEX": 21.26094283943617, "FILGRASTIM": 3.06413385708991, "FULVESTRANT": 30.172297113663348, "GEFITINIB": 36.13115434155291, "HERCEPTIN": 7.084990561471039, "INFLIXIMAB": 3.9776823642643135, "IPILIMUMAB": 6.438861607838036, "IRESSA": 8.774142922998356, "IRINOTECAN": 12.575021989705675, "JANUMET": 6.289501541293526, "JANUVIA": 7.623409756973144, "KISQALI": 16.481581218461102, "LONSURF": 2.995133353364316, "LYNPARZA": 3.5095021094296475, "MEKINIST": 14.76734707992742, "METHOTREXATE": 1.6610130065597912, "NEULASTA": 2.1302622244131606, "NEXAVAR": 35.83003586033936, "OLAPARIB": 14.223318352326697, "OPDIVO": 3.818139964867101, "OSIMERTINIB": 20.150139670735104, "PACLITAXEL": 8.522404990230545, "PAZOPANIB": 47.94854878515119, "PEMBROLIZUMAB": 2.1447424190208206, "PEMETREXED": 3.569441367978779, "REGORAFENIB": 39.116001822785215, "RIBOCICLIB": 36.50779916579864, "SORAFENIB": 30.543054872294285, "STIVARGA": 38.118732324234486, "TAFINLAR": 10.738587887181808, "TAGRISSO": 6.587186732999116, "VECTIBIX": 8.126174606056066, "VICTOZA": 1.0799941367607375, "VOTRIENT": 21.48019136910384, "XOFIGO": 20.97677760725499, "YERVOY": 6.801163194434338, "ZELBORAF": 3.695946709795381}
\ No newline at end of file
+{"ALIMTA": 2.3584151095808545, "ARAVA": 0.1323817599529301, "AVASTIN": 1.7877784324638, "BEVACIZUMAB": 1.9534761828635896, "BUDESONIDE": 0.644734652970958, "BUSULFAN": 4.392633473387216, "CAPECITABINE": 5.658196551538851, "CARMUSTINE": 6.744459938897255, "CELLCEPT": 3.443859176813701, "CICLOSPORIN": 0.4037896840739164, "COMBIVIR": 5.002335292413831, "CYTARABINE": 7.419154551259774, "DEXAMETHASONE": 1.9452778665213644, "DOCETAXEL": 16.79507584085875, "DOXORUBICIN": 22.541093690697405, "ERBITUX": 14.452791677852453, "FULVESTRANT": 5.263903805858065, "GANCICLOVIR": 8.080309076734414, "HALAVEN": 4.470671594109228, "HERCEPTIN": 4.194343384934607, "INTRONA": 6.98516733525301, "KEPPRA": 1.6004333305386609, "KISQALI": 3.3637159545179687, "LEVOFLOXACIN": 2.500471251929835, "MABTHERA": 12.529442163376215, "METHOTREXATE": 2.2518112010015363, "OLANZAPINE": 4.153480221278849, "PACLITAXEL": 10.155098290692544, "PEGASPARGASE": 22.927136602743246, "PEGASYS": 5.519188858185659, "PEGINTRON": 2.41502957317963, "PEMBROLIZUMAB": 1.7467930301798718, "PLAVIX": 4.275708434520027, "RIBAVIRIN": 2.226176488481406, "RIBOCICLIB": 6.447586491781753, "RITUXIMAB": 6.596194452730753, "ROACTEMRA": 1.181031485626946, "TAMIFLU": 1.6695821439266536, "TAXOTERE": 10.186004229820725, "XELODA": 9.19988947578254, "ZYPREXA": 2.1172158470176607, "null": 3.215843358567191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5229.json
index 7aa2b0529ee..aa2d550a2be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5229.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5229.json
@@ -1 +1 @@
-{"AFINITOR": 14.897583730474066, "ALIMTA": 1.7678777263976866, "AVASTIN": 6.847831531591747, "BEVACIZUMAB": 11.984289094093535, "BYETTA": 25.765809699884667, "CABAZITAXEL": 58.64291724211469, "CABOMETYX": 5.65517235426344, "CAELYX": 9.765847469944289, "CAPECITABINE": 28.009540242665626, "CELLCEPT": 2.5345057027326523, "CICLOSPORIN": 3.0571696577427687, "COSENTYX": 1.5719981781643868, "DABRAFENIB": 30.70553947850328, "DENOSUMAB": 56.437294754440025, "DOCETAXEL": 19.01086616611968, "ERLEADA": 6.249677927040783, "EVEROLIMUS": 24.873221042092617, "FASLODEX": 22.129557208961096, "FILGRASTIM": 5.741533166035016, "FULVESTRANT": 35.74068675046074, "GEFITINIB": 20.77716717434163, "HARVONI": 3.209468068523524, "HERCEPTIN": 7.10243917847237, "IPILIMUMAB": 4.478887375105418, "IRESSA": 13.49867076149224, "IRINOTECAN": 8.794897011381536, "JAKAVI": 2.305338622748669, "JANUMET": 16.911174490180073, "JANUVIA": 13.19697488441654, "KISQALI": 10.127196207173396, "LYNPARZA": 10.986428217050255, "MEKINIST": 18.56970240604992, "METHOTREXATE": 1.3913660200907811, "NEULASTA": 2.6874863182482165, "NEXAVAR": 11.363897750905126, "OLAPARIB": 16.58734584391089, "OPDIVO": 4.581561098716215, "OSIMERTINIB": 19.914064423452132, "PACLITAXEL": 13.60697261388922, "PAZOPANIB": 18.11540227348305, "RIBOCICLIB": 40.90150870083818, "STIVARGA": 14.775683567287034, "TAGRISSO": 7.505266377899103, "TRODELVY": 6.426408142046866, "VIAGRA": 3.624636339121254, "VOTRIENT": 6.438153289411878, "XOFIGO": 39.55039531435719, "XTANDI": 1.73333895083174}
\ No newline at end of file
+{"null": 1.713220839728608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/523.json
index 9289d20ab8d..4c076974747 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/523.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/523.json
@@ -1 +1 @@
-{"null": 1.067158724968268}
\ No newline at end of file
+{"null": 3.440318901667623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5230.json
index ac136240b3c..70e1a9957ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5230.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5230.json
@@ -1 +1 @@
-{"AFINITOR": 4.5901097025415, "ALIMTA": 9.324240708755696, "CAPECITABINE": 16.4393439860207, "DABRAFENIB": 59.98765145654069, "FASLODEX": 5.704001583287627, "GEFITINIB": 393.0899666966118, "IRESSA": 79.9672614942064, "IRINOTECAN": 23.15263988029885, "KEYTRUDA": 3.709840129301144, "KYMRIAH": 17.4087257488375, "LYNPARZA": 10.919971421604256, "MEKINIST": 29.611906397240787, "OPDIVO": 5.882507387465225, "OSIMERTINIB": 313.46420020359267, "TAGRISSO": 80.14189619352831, "TRODELVY": 37.27705422132789, "XOFIGO": 26.34510649230741}
\ No newline at end of file
+{"ABACAVIR": 1.961251477282365, "ABATACEPT": 2.029811566391851, "ACLIDINIUM": 23.244855531122948, "ADALIMUMAB": 3.10679708404994, "ALEMTUZUMAB": 10.314099597676462, "CELECOXIB": 9.121386530223866, "CICLOSPORIN": 3.479088617772321, "COMIRNATY": 0.1438735313292645, "EFAVIRENZ": 37.47050818838971, "ENTYVIO": 3.6075009964293816, "GARDASIL": 2.058729047525755, "IPILIMUMAB": 6.016820916352349, "JANUMET": 2.6031494108573514, "KEYTRUDA": 1.1703070364832224, "LAMIVUDINE": 10.70561463647167, "MEPOLIZUMAB": 10.249298806434682, "PEGASYS": 0.6473467209841854, "PEGINTERFERON": 5.031263637677742, "SPIKEVAX": 0.1465262667881616, "VAXZEVRIA": 0.0650737481291178, "XOLAIR": 1.8051274695040065, "null": 1.0621469685677525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5231.json
index ed0c9e7cdec..89f0a3feabd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5231.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5231.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 56.69051435988442, "FASLODEX": 42.62919988201436}
\ No newline at end of file
+{"ARAVA": 1.1125794936693891, "COMIRNATY": 1.055971690645324, "LANTUS": 3.131577575270952, "ROACTEMRA": 10.952167043308764, "SPIKEVAX": 0.4102820971801916, "TOZINAMERAN": 1.3204078059792623, "VAXZEVRIA": 0.4095359436646257, "null": 0.5566623580316882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5232.json
index bed796c08eb..53a90150e33 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5232.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5232.json
@@ -1 +1 @@
-{"AFINITOR": 17.951142535889385, "CABOMETYX": 55.95373952908467, "VOTRIENT": 22.25127026025585}
\ No newline at end of file
+{"FORXIGA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5233.json
index e0463107742..792da1cfc9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5233.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5233.json
@@ -1 +1 @@
-{"ABRAXANE": 264.92328007524685, "AVASTIN": 19.490208918049344, "FASLODEX": 28.67899269633443, "FULVESTRANT": 33.37662939641732, "OLAPARIB": 142.41297073437656, "STIVARGA": 26.880117247900117}
\ No newline at end of file
+{"ABATACEPT": 15.873460123118894, "ADALIMUMAB": 26.57819832385996, "APREMILAST": 113.51445573635232, "ARAVA": 9.64422837654782, "AZATHIOPRINE": 7.126480920719509, "CICLOSPORIN": 7.934798297854597, "COMIRNATY": 0.0437531919662224, "ENBREL": 73.05270481868115, "null": 0.119454016895145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5234.json
index c1ebdcfa612..ce279e1289d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5234.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5234.json
@@ -1 +1 @@
-{"ABRAXANE": 49.41912303055205, "AFINITOR": 16.39410410068564, "AVASTIN": 8.460768537383478, "BEVACIZUMAB": 19.64027420307878, "BYDUREON": 5.416495187854698, "BYETTA": 36.804315125463, "CABOMETYX": 5.543007576096178, "CAELYX": 32.53880288847138, "CAPECITABINE": 14.38048008724238, "DENOSUMAB": 26.360779971070592, "DOCETAXEL": 4.365230794928159, "FASLODEX": 14.683666866126794, "FULVESTRANT": 18.90708836760346, "GLIVEC": 34.11910597613456, "IMATINIB": 48.13174253446147, "IRINOTECAN": 23.422164326674043, "JANUMET": 32.591093776001884, "JANUVIA": 12.638973958185373, "LYNPARZA": 30.631896287468688, "MEKINIST": 10.160155812159358, "NEXAVAR": 11.751850587579357, "STIVARGA": 23.85734842534587, "VOTRIENT": 3.611108865173556}
\ No newline at end of file
+{"CICLOSPORIN": 3.956006506148308, "COMIRNATY": 1.0404509346402917, "SPIKEVAX": 0.4713377425188318, "VAXZEVRIA": 0.2741989352286826, "null": 0.9223077697710744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5235.json
index 6fd076bb036..ad716f9aca1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5235.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5235.json
@@ -1 +1 @@
-{"AFINITOR": 19.00742993054101, "BEVACIZUMAB": 20.34230163395972, "DOCETAXEL": 12.567505471785957, "FASLODEX": 29.299990245235925, "FULVESTRANT": 58.41925527347942, "IRESSA": 33.3072167061144, "NEXAVAR": 9.428577915943851, "RIBOCICLIB": 69.54439858823935, "TAGRISSO": 27.48685934398338}
\ No newline at end of file
+{"ARAVA": 4.924525643056774, "null": 0.1996297637353317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5236.json
index b29ed10d9cb..d0d49c3f099 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5236.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5236.json
@@ -1 +1 @@
-{"FASLODEX": 46.88225855015713}
\ No newline at end of file
+{"FUZEON": 906.3244014727634, "PEGASYS": 4.532703579706318, "null": 1.1434166841740538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5237.json
index a4264947e3a..c51be745f40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5237.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5237.json
@@ -1 +1 @@
-{"ABRAXANE": 81.71431836821557, "AFINITOR": 21.59419135596566, "CAPECITABINE": 72.23905247420778, "DABRAFENIB": 77.26958700981854, "DOCETAXEL": 18.2761915385294, "EVEROLIMUS": 93.9978510593902, "FASLODEX": 49.99263942988155, "FULVESTRANT": 22.289994602626408, "MEKINIST": 34.301064275930294, "VOTRIENT": 7.616249199893995}
\ No newline at end of file
+{"null": 0.3036851220416282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5238.json
index 27423be6426..dd161db73cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5238.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5238.json
@@ -1 +1 @@
-{"ADENURIC": 223.2416131666521}
\ No newline at end of file
+{"null": 1.5608023183884372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5239.json
index 88e25a0f048..0c9fb3647f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5239.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5239.json
@@ -1 +1 @@
-{"AFINITOR": 22.782134037202567, "BEVACIZUMAB": 7.493469205097857, "CABAZITAXEL": 65.18818324664026, "CABOMETYX": 12.997056285401468, "CANNABIDIOL": 37.158299060983616, "CAPECITABINE": 17.80566651191498, "DENOSUMAB": 61.8211325294319, "DOCETAXEL": 4.508553353777948, "ENZALUTAMIDE": 29.12586942559325, "EVEROLIMUS": 24.43880980660968, "FASLODEX": 31.372114579649264, "FULVESTRANT": 45.354334178589305, "IBRANCE": 2.542986041380823, "IRESSA": 11.360625521153604, "KISQALI": 35.82018120446954, "LYNPARZA": 10.11919456863008, "NEXAVAR": 16.876739383629452, "OLAPARIB": 41.00453127641667, "OPDIVO": 6.397980894324145, "PAZOPANIB": 23.342671409656152, "RIBOCICLIB": 37.56694829658316, "STIVARGA": 3.727047530953574, "TAGRISSO": 15.279311033087652, "VOTRIENT": 9.81058885925851, "XOFIGO": 72.41624308179424, "XTANDI": 5.766791176801762}
\ No newline at end of file
+{"ACLIDINIUM": 12.300312738030945, "AIMOVIG": 1.2328299607243776, "ALEMTUZUMAB": 47.36996760302877, "ATAZANAVIR": 7.175737360602633, "AUBAGIO": 1.631005228601494, "CHAMPIX": 0.8801317505472084, "CICLOSPORIN": 0.6103382856881104, "COMBIVIR": 3.986201971449111, "COMIRNATY": 1.5166835573499065, "COSENTYX": 1.137979349568011, "EFAVIRENZ": 13.71603784859098, "GARDASIL": 1.087912864855625, "HUMALOG": 1.1381086450497169, "KEYTRUDA": 2.1509895546126616, "LANTUS": 0.4543571392551025, "LEMTRADA": 126.52278402127328, "OPDIVO": 3.2690845328398903, "OPSUMIT": 1.0446520922237417, "PEGASYS": 4.517214762417995, "PEGINTERFERON": 7.60540509998259, "PEGINTRON": 12.593643762371324, "RIBAVIRIN": 7.182308576945927, "SPIKEVAX": 0.8932833492067357, "STELARA": 1.877133531135709, "TOZINAMERAN": 1.5731226660586204, "VAXZEVRIA": 0.357999317044427, "null": 0.3911660289890883}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/524.json
index 7408329f427..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/524.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/524.json
@@ -1 +1 @@
-{"ANORO": 334.8885519514293, "APIXABAN": 120.94204205228588, "AZATHIOPRINE": 46.01920140651239, "PANTOPRAZOLE": 51.87459937090336}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5240.json
index 9fecaef9e2a..d3231cbf983 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5240.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5240.json
@@ -1 +1 @@
-{"BYETTA": 30.26868209216557, "CYTARABINE": 17.512252148486507, "JANUMET": 41.19274318393758, "JANUVIA": 14.738469939243368, "MEKINIST": 22.585871291859128, "NEXAVAR": 11.90556601257187}
\ No newline at end of file
+{"ARAVA": 1.563155364353604, "COMIRNATY": 0.2334914155616594, "PEGASYS": 2.6643805846401776, "VAXZEVRIA": 0.1495884096582174, "null": 1.2261657615832804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5241.json
index 61419a42a2e..deae00fb401 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5241.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5241.json
@@ -1 +1 @@
-{"AFINITOR": 24.129649230925665, "CAPECITABINE": 47.4411592404888, "DOCETAXEL": 46.6027442241182, "FULVESTRANT": 49.8933315420318}
\ No newline at end of file
+{"COMIRNATY": 0.8376242799886215, "VAXZEVRIA": 0.4931249023390629, "null": 0.6395579106482814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5242.json
index 5e5d34a1ce7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5242.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5242.json
@@ -1 +1 @@
-{"FULVESTRANT": 182.33121832079317}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5243.json
index 4054b5e20fd..345f343827e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5243.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5243.json
@@ -1 +1 @@
-{"ABRAXANE": 30.71685088447018, "AFINITOR": 15.476127537598192, "AVASTIN": 5.908860087813162, "BEVACIZUMAB": 2.629886995062024, "BUSULFAN": 5.177259549220746, "CABAZITAXEL": 22.875354779777588, "CABOMETYX": 2.8260810925846016, "CAPECITABINE": 8.742747202471499, "COTELLIC": 15.896274964634316, "CYTARABINE": 2.3328121215426005, "DABRAFENIB": 11.510920545905874, "DEXAMETHASONE": 2.127094175150375, "DOCETAXEL": 21.238099804132546, "EVEROLIMUS": 12.058787052567316, "FASLODEX": 21.737343461616373, "FENTANYL": 1.0445089665157243, "FULVESTRANT": 23.47502587778088, "GEFITINIB": 23.41666785477021, "GLIVEC": 10.76041380931471, "HERCEPTIN": 4.809965350308519, "IBRANCE": 1.343535938516635, "IPILIMUMAB": 4.070435754520704, "IRESSA": 31.50917039552248, "JANUMET": 4.677292685727501, "JANUVIA": 3.160345485280885, "JEVTANA": 10.476867917269118, "KISQALI": 26.336611257910043, "LYNPARZA": 20.48839259768505, "MEKINIST": 23.40704979929865, "NEXAVAR": 6.630588623025816, "OSIMERTINIB": 21.220950133878887, "RIBOCICLIB": 18.504186471736244, "RITUXIMAB": 2.3220098721552054, "STIVARGA": 5.534298052188569, "TAGRISSO": 19.640796287052037, "TEMOZOLOMIDE": 11.842009849091328, "TRODELVY": 15.85493451381507, "VOTRIENT": 17.38652411379557, "XOFIGO": 56.17192846609832, "XTANDI": 6.664261700612534, "YERVOY": 6.750475518621078, "ZELBORAF": 13.484747460593926}
\ No newline at end of file
+{"null": 2.588873808515698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5244.json
index 58bee294a93..9b019f91dc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5244.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5244.json
@@ -1 +1 @@
-{"CARMUSTINE": 162.38853222426616}
\ No newline at end of file
+{"ZOSTAVAX": 14.151704087485523, "null": 2.2243297918405363}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5245.json
index 893e2eb668b..049707c3d5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5245.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5245.json
@@ -1 +1 @@
-{"ABACAVIR": 2.146734443215766, "BRAFTOVI": 18.72576582039307, "CIALIS": 398.3852834812421, "CICLOSPORIN": 1.4308756701042822, "COBIMETINIB": 95.22920200409833, "COTELLIC": 15.604456715116802, "DABRAFENIB": 398.4923391902726, "IPILIMUMAB": 21.94798157927847, "KEYTRUDA": 2.898609733216808, "MEKINIST": 184.77386873663477, "OPDIVO": 3.885011201384616, "TAFINLAR": 127.91629892137396, "TRAMETINIB": 432.5070243040728, "VIAGRA": 59.45174475157529, "ZELBORAF": 51.46286329880186}
\ No newline at end of file
+{"MIDAZOLAM": 42.87349808881051, "null": 1.7991395330553472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5246.json
index 683168184e5..8f2b19e076b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5246.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5246.json
@@ -1 +1 @@
-{"ABEMACICLIB": 107.1257911622265, "AVASTIN": 5.685191986693974, "BEVACIZUMAB": 9.884736656037571, "BYDUREON": 5.667639540984428, "BYETTA": 7.273380179448467, "CAPECITABINE": 9.325335904707348, "CLOPIDOGREL": 1.8951211674516024, "EPADERM": 756.3507176705792, "FASLODEX": 9.008988128446756, "FULVESTRANT": 12.260579057756733, "HERCEPTIN": 14.712173388250616, "IBRANCE": 1.83380336066334, "JANUMET": 5.386877084256314, "JANUVIA": 4.842037036549811, "LANTUS": 1.0516421370757842, "MEKINIST": 8.050283087717638, "NEXAVAR": 1.8131738214077624, "SIMPONI": 1.9125308467579205, "STELARA": 1.863742033539159, "VOTRIENT": 11.82295108728882, "XTANDI": 2.5766044654416627}
\ No newline at end of file
+{"ADALIMUMAB": 15.109736357403614, "AMINOSALICYLIC": 278.6191839434603, "VAXZEVRIA": 1.3785939378152716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5247.json
index e1bc8a2fa06..0a53d5df0b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5247.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5247.json
@@ -1 +1 @@
-{"AFINITOR": 10.201155270081228, "AXITINIB": 15.124255365368272, "CABOMETYX": 14.596056886098031, "EVEROLIMUS": 18.240195690993257, "INLYTA": 57.561952567542654, "NEXAVAR": 8.197947416268333, "PAZOPANIB": 52.539787273854216, "SORAFENIB": 30.86796027671447, "SUTENT": 207.67602263722588, "TORISEL": 46.4807089170371, "VOTRIENT": 26.658796092450817}
\ No newline at end of file
+{"ABATACEPT": 7.823468964933189, "ADALIMUMAB": 19.084379926190056, "ALEMTUZUMAB": 3.288554461047939, "ANAKINRA": 4.377738667125497, "APREMILAST": 93.42765945488998, "ARAVA": 3.0948660475633982, "AUBAGIO": 3.802632781357136, "CICLOSPORIN": 0.6004580983763653, "CIMZIA": 5.761603135850685, "COMIRNATY": 0.6228479366004572, "COSENTYX": 3.017078097717903, "ENBREL": 3.4561394243357157, "ENTYVIO": 1.8574595450493483, "GARDASIL": 1.5470951861899611, "HUMIRA": 4.322304163807522, "IBUPROFEN": 6.139970379343966, "LANTUS": 0.8384534938193358, "LEFLUNOMIDE": 8.326785607525586, "LYRICA": 1.5607454707509758, "METHOTREXATE": 29.2400604957555, "OPTIMARK": 2.8069519582839337, "PANTOPRAZOLE": 4.578118763484127, "RITUXIMAB": 1.7876588827186908, "SIMPONI": 0.9093831899714772, "SPIKEVAX": 0.4361190317165829, "TOZINAMERAN": 1.1462182072945108, "VAXZEVRIA": 0.1921871855572888, "XELJANZ": 3.4727923717025067, "XOLAIR": 1.6567193449328668, "null": 0.287310010225094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5248.json
index 95a267c2d86..e3fcada0d26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5248.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5248.json
@@ -1 +1 @@
-{"STELARA": 20.30149001189801}
\ No newline at end of file
+{"ADALIMUMAB": 2.570027423952936, "CIMZIA": 5.1510122468968245, "COMIRNATY": 0.2117688253370402, "JARDIANCE": 12.224563718058734, "SIMPONI": 9.825500938587751, "null": 0.4690326049596159}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5249.json
index 323f9900566..61c251cb491 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5249.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5249.json
@@ -1 +1 @@
-{"INVOKANA": 1190.3828331667223}
\ No newline at end of file
+{"CELLCEPT": 23.87627696721794, "JARDIANCE": 18.22155639316904, "null": 0.3221299234189435}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/525.json
index d9618a7dd83..cf8a35cc948 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/525.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/525.json
@@ -1 +1 @@
-{"COSENTYX": 6.426610524567921}
\ No newline at end of file
+{"BUPRENORPHINE": 24.164366861405085, "SUBOXONE": 16.06504125506405, "null": 2.1253513481003816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5250.json
index 04b7c67a0ec..4e4cb63eab6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5250.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5250.json
@@ -1 +1 @@
-{"CYTARABINE": 14.07186529698887, "FASTURTEC": 2326.180366476596, "IBUPROFEN": 7.733565513227944, "LEVOFLOXACIN": 11.068121497177764, "RASBURICASE": 3269.9253194698936, "null": 1.9810393223010527}
\ No newline at end of file
+{"AFINITOR": 0.727543682935904, "ARAVA": 0.3283092648426801, "BONVIVA": 5.077553307451468, "CAPECITABINE": 2.187006322456696, "CICLOSPORIN": 1.764049116110227, "CLOPIDOGREL": 0.9741276441481402, "COMIRNATY": 1.494554135347005, "COSENTYX": 1.3607797080957735, "CYMBALTA": 0.2987689437161784, "ELIQUIS": 0.7706406403110398, "ENBREL": 0.6481045665312358, "EVENITY": 6.792578362636017, "EXFORGE": 1.833164754143561, "FASLODEX": 1.7338403081649194, "FORSTEO": 3.8070888145895, "FORXIGA": 1.8942970468548237, "GARDASIL": 1.426344990493844, "HUMIRA": 3.33066359190656, "IBRANCE": 0.7277200005233917, "JARDIANCE": 0.6848616188367561, "KEYTRUDA": 0.4754177551591432, "PEMBROLIZUMAB": 2.294421122722232, "RINVOQ": 1.6205671885097954, "SHINGRIX": 2.6067607063008253, "SPIKEVAX": 1.2368337075825695, "SUTENT": 1.260569612544183, "TOZINAMERAN": 1.962408582718945, "VAXZEVRIA": 1.3895630794834672, "XELJANZ": 1.4507468558763992, "XTANDI": 1.8139524935889977, "ZOSTAVAX": 1.1181369747602332, "null": 0.6346690956902116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5251.json
index 4e21f5f4a85..dda22566c13 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5251.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5251.json
@@ -1 +1 @@
-{"GARDASIL": 132.95789170707545}
\ No newline at end of file
+{"null": 5.945524228397505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5252.json
index 135496ef4d2..003cb9d93f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5252.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5252.json
@@ -1 +1 @@
-{"EXFORGE": 10.277324364297993, "FORXIGA": 31.561539761373663, "HUMALOG": 18.042749946604467, "INSULIN": 8.421722293891142, "JANUMET": 7.622660228825891, "JARDIANCE": 5.327332361719206, "TRUVADA": 1.401490849145564, "ZYPREXA": 7.341479726927162}
\ No newline at end of file
+{"FORSTEO": 28.14653158629961, "SPIKEVAX": 3.127311648742324, "null": 0.6487643009059564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5253.json
index f8321f82dc1..f6b4067630a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5253.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5253.json
@@ -1 +1 @@
-{"AMIKACIN": 70.77640694401363, "CARFILZOMIB": 123.67520185412064, "CICLOSPORIN": 33.424592404565416, "KYPROLIS": 70.73904893702823, "SOLIRIS": 10.146375979739236}
\ No newline at end of file
+{"null": 2.214696680158027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5254.json
index 5a1850a403e..de75739c64a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5254.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5254.json
@@ -1 +1 @@
-{"BUSULFAN": 15.405417284640798, "CICLOSPORIN": 10.988982327127031, "METHOTREXATE": 55.12684820623129, "SOLIRIS": 9.029373011729698}
\ No newline at end of file
+{"null": 1.7523684511692792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5255.json
index 04c458f6983..6c04a7a6713 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5255.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5255.json
@@ -1 +1 @@
-{"COMBIVIR": 14.905457190049656, "IBUPROFEN": 10.311142660845665, "KEPPRA": 8.783099123555639, "null": 4.565595627530554}
\ No newline at end of file
+{"BUDESONIDE": 37.25875595641253, "null": 1.6190527138086976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5256.json
index a8fdb623c5a..42bacd1cdc0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5256.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5256.json
@@ -1 +1 @@
-{"ARAVA": 2.0069486068144857, "CLOPIDOGREL": 3.553955417121922, "ELIQUIS": 4.40117027565731, "PLAVIX": 7.310789076838037, "TORISEL": 34.65440871462857, "null": 1.1901251117309015}
\ No newline at end of file
+{"ASPARAGINASE": 42.254489806209534, "CYMBALTA": 9.343179309338437, "MICARDIS": 141.42414367164525, "null": 0.962906271449712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5257.json
index 285bf7933f4..23d1f14f88d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5257.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5257.json
@@ -1 +1 @@
-{"ASENAPINE": 2486.398161409357, "COMBIVIR": 171.16376157047154}
\ No newline at end of file
+{"BUDESONIDE": 8.20345612096366, "CANAKINUMAB": 397.05889983740735, "CICLOSPORIN": 6.51054184221271, "CYMBALTA": 1.4281769594013094, "FLUTICASONE": 69.44089591960237, "HYDROCORTISONE": 5.65537225485269, "KEPPRA": 3.844087876823985, "METHOTREXATE": 6.368863295029495, "OMNITROPE": 106.84320022944836, "ROTATEQ": 5.562266355780661, "null": 3.930235676744311}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5258.json
index b65fc305ae7..3fa967be725 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5258.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5258.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.077336483794247}
\ No newline at end of file
+{"COMIRNATY": 0.308931134820023, "GARDASIL": 5.4154000492976, "TOZINAMERAN": 1.289407177787973, "null": 1.4137336672913603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5259.json
index 712dd626728..2be6b591db6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5259.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5259.json
@@ -1 +1 @@
-{"null": 2.0925266228089137}
\ No newline at end of file
+{"AMIKACIN": 1.8237268755068787, "APIXABAN": 1.3801262114976676, "BEXSERO": 3.534322219722199, "BIKTARVY": 0.9536110605641592, "BRAFTOVI": 1.151701961380143, "BUSULFAN": 2.5049190905976544, "CAPECITABINE": 0.929580731701021, "CELLCEPT": 0.4382622363068562, "CICLOSPORIN": 0.6261477443773935, "CIMZIA": 0.1585486810978278, "COMIRNATY": 1.5988129876192487, "COSENTYX": 0.4384276413379724, "DEXAMETHASONE": 0.6134336384675352, "ENBREL": 0.3119284560447114, "ENTYVIO": 0.6971072256376503, "EPIVIR": 2.279550551440222, "FLUCELVAX": 9.287196737883969, "GARDASIL": 8.890485041552422, "HUMAN": 2.3014325447121804, "HUMIRA": 0.6300176141651307, "IPILIMUMAB": 7.194192879250318, "KEYTRUDA": 3.184928289240782, "LEVETIRACETAM": 1.11662109778435, "MABCAMPATH": 13.43619225958807, "MENVEO": 5.002027772462974, "MMRVAXPRO": 0.8001625348551201, "MODERNA": 0.988972882737322, "NIMENRIX": 2.0029548703560405, "OPDIVO": 3.6578166407226256, "PEGASYS": 0.6123958493206304, "PEGINTERFERON": 1.2497691262129766, "PEGINTRON": 1.5265590610988369, "PEMBROLIZUMAB": 3.498801080312312, "PREVENAR": 4.56651240347074, "RAPAMUNE": 1.9041460026811607, "SHINGRIX": 13.12763770515259, "SIMPONI": 0.6468480534599372, "SPIKEVAX": 1.0561180749493742, "STELARA": 1.0047839312212017, "SUTENT": 0.2625399572402542, "TOZINAMERAN": 2.412747139980594, "TWINRIX": 12.979841354061328, "VAXZEVRIA": 3.2658442909301035, "VFEND": 1.970564485599464, "YERVOY": 4.97783944956507, "ZOSTAVAX": 2.992259022727743, "null": 0.3624673456023569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/526.json
index beff19f2a4f..6f1ec2f3cdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/526.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/526.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.389627332397746, "AIMOVIG": 3.1776023626917387, "ARAVA": 1.1803905456822656, "CELECOXIB": 9.359985871974756, "CICLOSPORIN": 2.3375258538363157, "COSENTYX": 1.4284708112523925, "DEXAMETHASONE": 2.8132376218259, "EMPAGLIFLOZIN": 20.817546563769028, "ENBREL": 2.532852673095394, "GARDASIL": 3.7864937317592338, "PEGASYS": 1.1205227906440145, "PEGINTRON": 1.7871334190794834, "STELARA": 2.854883889814624, "XOLAIR": 2.757847378933025, "null": 1.8570707845610237}
\ No newline at end of file
+{"null": 1.710304764804888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5260.json
index c12769ed1f8..840f8f23220 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5260.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5260.json
@@ -1 +1 @@
-{"METHOTREXATE": 16.766266809103005, "null": 4.939258664128763}
\ No newline at end of file
+{"FENTANYL": 5.652494748975029, "SUBOXONE": 37.68862266788788, "null": 3.078020186445883}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5261.json
index e0942f72557..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5261.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5261.json
@@ -1 +1 @@
-{"null": 1.1422885138152594}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5262.json
index f771f620527..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5262.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5262.json
@@ -1 +1 @@
-{"null": 2.182707492679382}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5263.json
index 3223e6e8f72..91487c7908f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5263.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5263.json
@@ -1 +1 @@
-{"null": 2.916728444196855}
\ No newline at end of file
+{"CICLOSPORIN": 4.634057460775123, "CIMZIA": 3.691014670204133, "COMIRNATY": 1.1241827611745865, "COSENTYX": 11.370348961748691, "SPIKEVAX": 0.6065000005767066, "STELARA": 29.40302661617941, "TOZINAMERAN": 0.7210892173536855, "TREMFYA": 30.663619627956813, "VAXZEVRIA": 0.9086601872572436, "null": 0.2619759992794246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5264.json
index 74299653b9f..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5264.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5264.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1915816642481352}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5265.json
index eb66b8085ef..2ffd12adb4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5265.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5265.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 265.35095102493494, "CICLOSPORIN": 26.45077194744592}
\ No newline at end of file
+{"ABILIFY": 5.553865372400018, "ARIPIPRAZOLE": 5.565816411905163, "ATRIPLA": 0.8669006268877889, "BIKTARVY": 4.400034294832929, "BRILIQUE": 1.3106765706803123, "BRINTELLIX": 1.3594461489891536, "CLOPIDOGREL": 2.19882329765898, "COMBIVIR": 3.2681477364346936, "COMIRNATY": 0.0658889021734415, "CYMBALTA": 0.4342915234187502, "EFAVIRENZ": 9.480367940897343, "ELIQUIS": 0.3394056700466412, "ENTRESTO": 4.515124351117639, "ENZALUTAMIDE": 8.337607562842555, "EXFORGE": 3.0080356730993576, "INVEGA": 92.28047410441224, "ISENTRESS": 2.899085785998296, "JANUVIA": 1.010316666896486, "JARDIANCE": 0.7855385975667301, "KAFTRIO": 3.0767791959763238, "KALETRA": 1.177768367026675, "KEYTRUDA": 0.2582993032154858, "MICARDIS": 2.587408685157932, "NORVIR": 3.833056649095538, "OLANZAPINE": 2.882390816938738, "OPSUMIT": 0.6249982908743235, "PLAVIX": 0.9609741007312828, "PRIVIGEN": 3.7078464164328473, "RASILEZ": 3.058078914914629, "REYATAZ": 9.93630983269045, "RISPERIDONE": 14.851192660703886, "SPIRONOLACTONE": 15.513178101531572, "STELARA": 0.4401661754868647, "STOCRIN": 32.00288477148004, "SUTENT": 0.2876937730692753, "TASIGNA": 1.6772523732067783, "TESTOSTERONE": 7.10372429034173, "UROREC": 16.825726505283956, "VAXZEVRIA": 0.0143625050635942, "XTANDI": 2.51981684479072, "ZYPREXA": 9.252248870444353, "null": 3.801078532738508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5266.json
index b0537d2dbc0..6cf090a3468 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5266.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5266.json
@@ -1 +1 @@
-{"null": 1.561918659840594}
\ No newline at end of file
+{"CELLCEPT": 10.88361965789094, "CICLOSPORIN": 5.084382400885404, "INTELENCE": 147.18136326792742, "SYNAGIS": 26.584753479197943, "TAMIFLU": 108.54891770019869, "null": 0.7072262816667427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5267.json
index 5f04f70901e..66004af64db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5267.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5267.json
@@ -1 +1 @@
-{"CELLCEPT": 62.236788757969975, "null": 1.2199126845533774}
\ No newline at end of file
+{"COMIRNATY": 0.2390188169343158, "null": 2.627329092220702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5268.json
index 175e1e8bbe2..e525a3d6533 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5268.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5268.json
@@ -1 +1 @@
-{"null": 3.6147353771008457}
\ No newline at end of file
+{"DOCETAXEL": 60.193124052351465, "HERCEPTIN": 100.46124334043576, "null": 0.3731052279235446}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5269.json
index 5df2d467966..9b9968c69e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5269.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5269.json
@@ -1 +1 @@
-{"CYMBALTA": 1.7670160420545338, "FORXIGA": 3.838346858488418, "INCRUSE": 12.138668609296312, "IRON": 20.092337341910685, "JARDIANCE": 3.537439051433315, "NUCALA": 1.7906826561328288, "TOVIAZ": 16.291095437403083, "TRELEGY": 5.216566251678753, "VIAGRA": 2.5469118237308632, "ZYPREXA": 2.2019781419053555, "null": 2.3821266380902024}
\ No newline at end of file
+{"BEVACIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/527.json
index ee99753930f..345f343827e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/527.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/527.json
@@ -1 +1 @@
-{"OLANZAPINE": 32.25696391938091}
\ No newline at end of file
+{"null": 2.588873808515698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5270.json
index 092c789a342..439c968904e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5270.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5270.json
@@ -1 +1 @@
-{"IBUPROFEN": 47.07804721196963, "JARDIANCE": 5.963639909434095, "null": 1.9599486513903035}
\ No newline at end of file
+{"DOCETAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5271.json
index 15fdaa8daba..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5271.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5271.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 1.17541888565027, "AUBAGIO": 4.443833465903453, "AZILECT": 21.221128594536346, "BETMIGA": 16.102872177207068, "BRINTELLIX": 1.5030205439510866, "ELMIRON": 80.6509196419714, "EXFORGE": 5.286877279446814, "FAMPYRA": 4.095215788715235, "FASLODEX": 2.0256556982193974, "FORSTEO": 9.363612741052922, "FORXIGA": 9.496834676371662, "JARDIANCE": 12.70208558453816, "MICARDIS": 1.9450757175024165, "NOT": 3.395840337597743, "OXYBUTYNIN": 13.688573523647792, "TOVIAZ": 23.460789938807768, "XELJANZ": 1.468320113881998, "XTANDI": 1.8861844114186408, "ZOSTAVAX": 1.2084805172355002, "null": 1.4230276412518692}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5272.json
index ea781cdb256..3c4f9bd6c1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5272.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5272.json
@@ -1 +1 @@
-{"COVID19": 1.0227716476688424, "ELIQUIS": 12.256099977060725}
\ No newline at end of file
+{"ABACAVIR": 12.6857707366339, "AMINOSALICYLIC": 21.48713133078371, "BIKTARVY": 30.24915229169567, "DACLATASVIR": 94.41371560596392, "DARUNAVIR": 49.07284387317901, "DELAMANID": 69.40456006323075, "DESCOVY": 82.13567411867415, "EFAVIRENZ": 96.4603203157973, "EMTRICITABINE": 46.538992949554846, "ISENTRESS": 26.20435061450971, "KALETRA": 14.629881321238097, "LAMIVUDINE": 84.26817768120603, "NORVIR": 27.34268683994153, "STELARA": 5.53850291113557, "TRUVADA": 4.125121315088141, "VIAGRA": 4.956590106852047, "null": 0.5232331789214322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5273.json
index bf2a27668c2..9152205e8d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5273.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5273.json
@@ -1 +1 @@
-{"null": 1.6954522483523864}
\ No newline at end of file
+{"LAMIVUDINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5274.json
index c763e0b3c01..a4fc3433a26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5274.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5274.json
@@ -1 +1 @@
-{"null": 1.013607895875657}
\ No newline at end of file
+{"TIVICAY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5275.json
index 15bab7dcc21..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5275.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5275.json
@@ -1 +1 @@
-{"COMIRNATY": 1.281875706839827, "SPIKEVAX": 1.89811584226407, "null": 1.0309609352421476}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5276.json
index eedac25aa33..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5276.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5276.json
@@ -1 +1 @@
-{"AIMOVIG": 7.415357607661773, "AVAMYS": 3.040514724276893, "BIKTARVY": 2.039092749231868, "BRINTELLIX": 3.369377829495865, "BUDESONIDE": 16.581529434744848, "CHAMPIX": 1.8547917960823737, "CIRCADIN": 21.07027534721172, "CPAP": 160.24441423630603, "EFAVIRENZ": 3.973115202063137, "ESBRIET": 1.7678180464331557, "FASENRA": 4.018446164159955, "FLUTICASONE": 5.905972825192549, "HUMIRA": 3.608948557418156, "JANUVIA": 1.2447859237494174, "KAFTRIO": 9.652365329911897, "LATUDA": 2.0868334972548768, "LYRICA": 1.312869139372379, "MELATONIN": 46.09640544647803, "MEPOLIZUMAB": 12.0458594243768, "MMRVAXPRO": 1.8565523456272812, "NUCALA": 6.172075998563005, "OLANZAPINE": 1.1580129850981151, "OMALIZUMAB": 25.712367272315667, "PANTOPRAZOLE": 1.5899364435338164, "PREGABALIN": 10.034790778955744, "RINVOQ": 3.581925439903827, "SLENYTO": 108.16237748116951, "TOVIAZ": 5.353819996751486, "TRELEGY": 1.3616414948353408, "XELJANZ": 2.046899917943348, "XOLAIR": 3.682727916880797, "null": 1.0721757709953212}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5277.json
index 3be0964c9dd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5277.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5277.json
@@ -1 +1 @@
-{"AIMOVIG": 28.98863992328096, "AJOVY": 6.846093138431921, "APIXABAN": 2.2236352577719205, "APREMILAST": 2.620634789629685, "AUBAGIO": 1.0249657311601352, "AVAMYS": 1.4259217306043332, "BELIMUMAB": 1.2809832081449355, "BENLYSTA": 1.892005078836748, "BOTULINUM": 28.4761202693563, "BRINTELLIX": 1.2593991739566424, "CELECOXIB": 2.1958011650187097, "CIRCADIN": 1.4327364752163427, "COMIRNATY": 1.536810640189796, "COVID19": 3.8096253557000335, "CYMBALTA": 1.3688707137663956, "EMGALITY": 21.79360439143026, "ERENUMAB": 22.81362551475834, "ESMYA": 1.1169347886857948, "EVRA": 1.5986903268627877, "FIRDAPSE": 1.06289705436245, "FLUCELVAX": 1.0637290551870575, "GARDASIL": 2.355015301968417, "GILENYA": 1.062638633088275, "HIZENTRA": 2.5997491242597524, "HUMIRA": 1.1078194286488434, "HYQVIA": 1.3608940127385984, "IXIARO": 3.260808789662923, "KALYDECO": 1.091979194276287, "KESIMPTA": 1.058480573121137, "LYRICA": 1.3132154765703257, "OMALIZUMAB": 1.265960247761991, "PLEGRIDY": 1.0329695169670363, "PRIVIGEN": 1.4021440135647054, "PROPRANOLOL": 1.685239648677589, "RUCONEST": 1.381741240940003, "SAXENDA": 1.3513557612238982, "SPIKEVAX": 1.2608121672232842, "SUBOXONE": 1.0051790372954834, "TOZINAMERAN": 3.1160555892674657, "VAXZEVRIA": 1.2775604276994976, "XOLAIR": 1.1839044256186813, "XYREM": 2.75245547697651, "ZONEGRAN": 4.0665620084698375, "ZONISAMIDE": 4.844660135959851}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5278.json
index b1aa3ee4d50..f2fb1597afb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5278.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5278.json
@@ -1 +1 @@
-{"AIMOVIG": 10.56067372608402, "AZATHIOPRINE": 2.5572870575290905, "BELIMUMAB": 18.825022305191485, "BOTULINUM": 18.85873440850666, "CICLOSPORIN": 1.4934328202010163, "COMIRNATY": 2.3141641579140586, "COVID19": 3.545596431366792, "GARDASIL": 3.4332702480461625, "SPIKEVAX": 1.2821283445941354, "TOZINAMERAN": 4.006577048301333, "VAXZEVRIA": 1.1712488160267602}
\ No newline at end of file
+{"CYMBALTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5279.json
index 672f649e714..5c1122093b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5279.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5279.json
@@ -1 +1 @@
-{"AIMOVIG": 15.321054923766384, "COVID19": 1.9793961044160304, "CYMBALTA": 3.623549546504935, "ERENUMAB": 173.33544977004564, "GARDASIL": 9.275656764706726, "TOZINAMERAN": 1.3454073978459549, "ZOSTAVAX": 6.890266185386682}
\ No newline at end of file
+{"KALETRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/528.json
index 0366cbfb84a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/528.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/528.json
@@ -1 +1 @@
-{"STELARA": 10.04441511834412, "null": 1.460808871659261}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5280.json
index c30be23753e..54e8a7188a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5280.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5280.json
@@ -1 +1 @@
-{"COVID19": 4.115383950897705, "TOZINAMERAN": 3.71973640993095}
\ No newline at end of file
+{"ATAZANAVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5281.json
index 7615b9442c6..821201f9372 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5281.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5281.json
@@ -1 +1 @@
-{"ABILIFY": 10.856886804758512, "ROTATEQ": 216.33844959140868, "null": 1.533263101034518}
\ No newline at end of file
+{"ISENTRESS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5282.json
index 2858f4b04ef..aaaccbf1bdf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5282.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5282.json
@@ -1 +1 @@
-{"null": 3.358155988248352}
\ No newline at end of file
+{"TRUVADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5283.json
index 8647d6f257c..5faba73fbe4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5283.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5283.json
@@ -1 +1 @@
-{"COMIRNATY": 2.213068882010747, "COVID19": 1.5708658691675377, "GARDASIL": 4.201598200555135, "SPIKEVAX": 1.007943161514555, "VAXZEVRIA": 2.725949081506543}
\ No newline at end of file
+{"BIKTARVY": 41.80907631172655, "DESCOVY": 154.89261518741472, "EMTRICITABINE": 108.94046551656396, "KALETRA": 26.43681284633029, "STRIBILD": 8.126243426562583, "TRUVADA": 26.20451359067532, "VIAGRA": 15.282436861438102, "null": 0.3028371153170485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5284.json
index 544e1839b81..0d43b6cc1d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5284.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5284.json
@@ -1 +1 @@
-{"null": 1.256579993351517}
\ No newline at end of file
+{"BIKTARVY": 118.78717738244588, "DARUNAVIR": 656.8725332715977, "EFAVIRENZ": 118.22051711534051}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5285.json
index e1f831d55ec..6433a5c5b1c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5285.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5285.json
@@ -1 +1 @@
-{"ELIQUIS": 9.854581840918367, "OPSUMIT": 62.02983418708365, "TRACLEER": 43.14966987734736}
\ No newline at end of file
+{"DARUNAVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5286.json
index 6384ced8628..a16bc29d627 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5286.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5286.json
@@ -1 +1 @@
-{"MITOTANE": 28927.234211841896}
\ No newline at end of file
+{"ABACAVIR": 40.65245686934084, "BIKTARVY": 33.207019396040145, "COMBIVIR": 50.75525594379243, "EMTRICITABINE": 148.60740218812705, "LAMIVUDINE": 120.47572943055047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5287.json
index 34e7a0795e8..4f457658be6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5287.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5287.json
@@ -1 +1 @@
-{"null": 2.5322569562112758}
\ No newline at end of file
+{"ENBREL": 123.38315335318828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5288.json
index ab805b7f21e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5288.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5288.json
@@ -1 +1 @@
-{"AZACITIDINE": 124.9021968373036, "CLOPIDOGREL": 9.27448047184934, "CYTARABINE": 33.544187395813935, "KYMRIAH": 403.7936048847712, "VENETOCLAX": 273.2854754181052}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5289.json
index b6bb8c888b9..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5289.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5289.json
@@ -1 +1 @@
-{"CUBICIN": 685.2128261388098, "DAPTOMYCIN": 5070.275694688478}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/529.json
index ee614f0e114..5b5a98deb97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/529.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/529.json
@@ -1 +1 @@
-{"BENLYSTA": 6.886619903555781, "ELIQUIS": 7.997121519995715, "GARDASIL": 6.271562033230672, "SOLIRIS": 6.005879457919846, "TOZINAMERAN": 1.023064412227452}
\ No newline at end of file
+{"CAPECITABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5290.json
index 9d7c89f0623..26ee34bfad8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5290.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5290.json
@@ -1 +1 @@
-{"ABILIFY": 1.484379658009216, "BENZODIAZEPINE": 11.58012151830402, "BIKTARVY": 2.1669781331918214, "BRINTELLIX": 1.0845372443222228, "BUPRENORPHINE": 20.801779228987996, "DULOXETINE": 2.281697224267688, "FENTANYL": 5.749754174117107, "IBUPROFEN": 2.683210750961254, "KEPPRA": 2.130490878890328, "LYRICA": 4.55360670432247, "MIDAZOLAM": 5.535696703805512, "NALOXONE": 65.87776609155605, "OLANZAPINE": 9.239520544131192, "PREGABALIN": 16.05252066141492, "SODIUM": 51.29912456556964, "SUBOXONE": 4.720773098128257, "SUFENTANIL": 9.856369291838975, "VFEND": 1.0246277658848215, "ZYPADHERA": 7.962094257083629, "ZYPREXA": 6.142805859887483, "null": 5.611761010374255}
\ No newline at end of file
+{"null": 0.6192836920493578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5291.json
index 7d84c6bd417..26dd8a1ddf2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5291.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5291.json
@@ -1 +1 @@
-{"HUMAN": 442.7832890143675, "null": 1.1017941805452511}
\ No newline at end of file
+{"CABOTEGRAVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5292.json
index 94fcfee05c9..87d26556251 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5292.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5292.json
@@ -1 +1 @@
-{"ANORO": 803.8175693667865, "APIXABAN": 136.10388769069826, "AZATHIOPRINE": 34.478415398783895, "BUDESONIDE": 2.687102036427533, "MEPOLIZUMAB": 15.757386825678555}
\ No newline at end of file
+{"MULTAQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5293.json
index 11ef01615a2..b49973be1eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5293.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5293.json
@@ -1 +1 @@
-{"INTELENCE": 4803.567854497512}
\ No newline at end of file
+{"null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5294.json
index 43ed108b00a..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5294.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5294.json
@@ -1 +1 @@
-{"BIKTARVY": 106.42441620614947, "DEXAMETHASONE": 140.37039197993863, "LEVETIRACETAM": 48.901741466100425}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5295.json
index 810f172f389..40fa1ce0c5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5295.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5295.json
@@ -1 +1 @@
-{"ABACAVIR": 15.408894107948033, "ATRIPLA": 1.5644146873039737, "COMBIVIR": 52.83260521541753, "COMIRNATY": 1.8076242719474973, "INVIRASE": 188.1958555668036, "VIREAD": 34.07459120981709}
\ No newline at end of file
+{"VAXZEVRIA": 6.333110207060727}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5296.json
index 215369fa141..0cb2776bceb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5296.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5296.json
@@ -1 +1 @@
-{"null": 2.0384881070613017}
\ No newline at end of file
+{"ABILIFY": 3.313361887584079, "ASPARAGINASE": 22.35483115503358, "COMIRNATY": 0.4416723596282064, "ELIQUIS": 1.1010184670392125, "GARDASIL": 1.8014067267425162, "KEPPRA": 2.5344356121319214, "LEVETIRACETAM": 7.876656868223224, "SPIKEVAX": 0.3292110923668251, "SUTENT": 1.045127275080111, "VAXZEVRIA": 0.3475029173870994, "null": 1.279144858245484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5297.json
index 744d799ea36..cb8b5c700ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5297.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5297.json
@@ -1 +1 @@
-{"null": 2.848173647013041}
\ No newline at end of file
+{"null": 3.306605669291395}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5298.json
index 79b34cf194f..a8588ac8c05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5298.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5298.json
@@ -1 +1 @@
-{"ABACAVIR": 154.91757398474897}
\ No newline at end of file
+{"JANUMET": 65.89345285284487}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5299.json
index e19f1f69d7b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5299.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5299.json
@@ -1 +1 @@
-{"INTELENCE": 1634.87883964271}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/53.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/53.json
index 0c6ed5351e7..447b4f36c1c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/53.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/53.json
@@ -1 +1 @@
-{"null": 2.439933410514347}
\ No newline at end of file
+{"VAXZEVRIA": 0.9149615433676612, "null": 1.157801816178564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/530.json
index 886199c8d75..4bc7996fc89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/530.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/530.json
@@ -1 +1 @@
-{"null": 1.9021034470265756}
\ No newline at end of file
+{"CELECOXIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5300.json
index f76bc8a430b..e57d8224ef2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5300.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5300.json
@@ -1 +1 @@
-{"ABACAVIR": 169.22159041294174, "ATAZANAVIR": 116.3955291996319, "CRIXIVAN": 171.58590705123788, "ENFUVIRTIDE": 579.3875928474247, "IBUPROFEN": 6.304984210756544, "INTELENCE": 108.03239645820874, "KALETRA": 16.355617336897613, "LAMIVUDINE": 45.18824138855129, "RIBAVIRIN": 11.496602397107832, "SAQUINAVIR": 1873.104789775333, "TRUVADA": 1.2455015607996498}
\ No newline at end of file
+{"COMIRNATY": 0.2008909910715482, "ESMYA": 99.47312502887094, "JANUMET": 12.136357336474797, "JANUVIA": 10.909889206594755, "PEGASYS": 3.0180354213133453, "null": 0.9074039225728028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5301.json
index 439e34aae45..b2423b61c32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5301.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5301.json
@@ -1 +1 @@
-{"null": 2.040534036553507}
\ No newline at end of file
+{"COMIRNATY": 0.5393594056901613, "COSENTYX": 12.867725091094544, "VAXZEVRIA": 1.0677186167902566, "ZOSTAVAX": 9.082945005309467, "null": 0.6898331367641963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5302.json
index 10b88d4942a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5302.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5302.json
@@ -1 +1 @@
-{"null": 1.469345218101073}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5303.json
index 82895b560f9..38da6547cf6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5303.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5303.json
@@ -1 +1 @@
-{"AVANDIA": 15.396607845184848, "CLOPIDOGREL": 3.0435752408174177, "ELIQUIS": 10.502652934576904, "FYCOMPA": 34.563785348141884, "null": 1.6187720071640774}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5304.json
index 29168bf4e24..5d053d22d01 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5304.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5304.json
@@ -1 +1 @@
-{"AFINITOR": 1.4954447039567644, "APIXABAN": 2.9908560542017755, "APROVEL": 5.842035632098304, "ARIPIPRAZOLE": 3.930243467468784, "AVANDAMET": 8.707804642688046, "AVANDIA": 9.88420787721383, "BEDAQUILINE": 5.812120385904112, "BRILIQUE": 5.302599318604846, "BUMETANIDE": 42.96962464155932, "CELECOXIB": 2.9873960499119057, "CLOPIDOGREL": 2.904069873189179, "DAPAGLIFLOZIN": 19.106363225878475, "DASATINIB": 11.946417822285056, "DOCETAXEL": 1.2204177867668364, "DULOXETINE": 2.4114463125913623, "EDOXABAN": 46.51361941766905, "ELIQUIS": 2.535094015418429, "EMPAGLIFLOZIN": 4.298817735758627, "ENTRESTO": 12.87866634901938, "EVISTA": 3.2761629132493844, "EXJADE": 1.2151065046134228, "FORSTEO": 1.1642005671322222, "HERCEPTIN": 5.941691618514279, "ICLUSIG": 4.1329524260223565, "INTEGRILIN": 15.995202876832636, "IRBESARTAN": 6.211170183147972, "IVABRADINE": 35.82421899676855, "JANUVIA": 1.5078491486858814, "KALETRA": 1.3779689407852171, "NAGLAZYME": 18.558064266761303, "PANTOPRAZOLE": 3.5131424198356003, "SPIRONOLACTONE": 6.882078331051297, "TASIGNA": 6.256271534798794, "VALSARTAN": 17.814205263909184, "XOLAIR": 1.1019255633102856, "ZOSTAVAX": 2.440923727544879, "ZYPREXA": 1.2405942062573911, "null": 1.6870041101215316}
\ No newline at end of file
+{"ABACAVIR": 0.3669220601432031, "ADALIMUMAB": 0.5017925559361265, "ADCIRCA": 2.932683072765768, "ADVATE": 3.7586044117679593, "AFINITOR": 0.5776848906972766, "ALIMTA": 0.6647071055299635, "APIDRA": 0.4379648146005897, "APIXABAN": 1.3277199736312342, "APREPITANT": 7.128287150578749, "ARANESP": 0.2935598275763537, "ARAVA": 0.2049905307572772, "ARIXTRA": 15.21036327493926, "ASPARAGINASE": 0.8379790734398306, "AVASTIN": 1.7724830166808956, "AZATHIOPRINE": 0.5454050922029381, "BENLYSTA": 0.6006816133938718, "BEVACIZUMAB": 0.5370395101307699, "BLINCYTO": 9.98531170035907, "BONVIVA": 1.189366405732349, "BRILIQUE": 7.43085591863739, "BRINTELLIX": 0.3113268399581971, "BUPRENORPHINE": 0.6299031200148725, "BUSULFAN": 0.4741862266105453, "BYDUREON": 1.0474049772483809, "BYETTA": 0.34138373755128, "CABOMETYX": 0.6464180041402176, "CAPECITABINE": 0.6569250446975173, "CELECOXIB": 1.1139522768825194, "CELLCEPT": 0.6869144230145878, "CHAMPIX": 1.7214917737256734, "CICLOSPORIN": 0.2441552561571309, "CIMZIA": 0.1120440277561764, "CLOPIDOGREL": 26.534114989742847, "COMIRNATY": 0.1281943105134622, "COSENTYX": 0.2523531944039905, "CYMBALTA": 0.4963304836554238, "CYTARABINE": 0.4622920671429717, "DAKLINZA": 2.381578611272152, "DEXAMETHASONE": 0.7877621300174447, "DULOXETINE": 0.7162939653791581, "EFIENT": 4.721670751530465, "ELIQUIS": 5.283920632972277, "ENOXAPARIN": 9.685239716417684, "ENTRESTO": 0.3018145627642432, "EPCLUSA": 1.8421668250610623, "EPIVIR": 1.2564458550327866, "ESBRIET": 0.6532820271944054, "EVEROLIMUS": 2.176877076703062, "EXFORGE": 0.4294045904456961, "EXJADE": 2.0013752884498905, "EXVIERA": 2.2425592430465566, "FORSTEO": 0.4676990369246923, "GARDASIL": 0.4089963176465013, "HARVONI": 1.756470139489148, "HUMALOG": 0.3279772182833413, "IBRANCE": 0.4127181111073444, "IBUPROFEN": 3.154722094241915, "INCIVO": 0.5431609262470918, "INLYTA": 1.3252821694925256, "INTEGRILIN": 15.603142729759774, "INVOKANA": 1.8968569634703645, "IRBESARTAN": 0.9061192326850694, "IRESSA": 1.1011568469830928, "ISCOVER": 20.046321897187752, "JAKAVI": 1.0905451007243676, "JANUMET": 0.3556723454056745, "JANUVIA": 0.680171780209056, "JARDIANCE": 0.2612928380432754, "KEPPRA": 0.2375417603474638, "KEYTRUDA": 0.2978642923096522, "LANTUS": 0.2938250074196969, "LENVIMA": 2.7621038279843253, "LEVOFLOXACIN": 0.1963298733945895, "LIXIANA": 4.9069930310897645, "LONSURF": 1.1244942527955513, "MEKINIST": 0.5959615599129952, "METHOTREXATE": 0.8583687507704731, "MIDAZOLAM": 0.7272150769598011, "NEXAVAR": 4.565769928899651, "OFEV": 0.8545368787809114, "OLANZAPINE": 0.2588155611930463, "OLYSIO": 1.7336035595131816, "OPDIVO": 0.6158487151433168, "OPSUMIT": 0.8959388610796271, "PANTOPRAZOLE": 0.5876947461135816, "PEGASYS": 2.2337785705808004, "PEGINTERFERON": 0.9643743439009846, "PEGINTRON": 1.3117990335162275, "PLAVIX": 17.435235208672296, "PRADAXA": 7.380582367365746, "RIBAVIRIN": 1.699108056940149, "RITUXIMAB": 0.374238941390212, "RIVAROXABAN": 3.451328955769747, "ROTATEQ": 2.1926199410130622, "SAXENDA": 1.3906883242724182, "SOLIRIS": 0.6669660887109096, "SOVALDI": 3.0708755356390083, "SPIKEVAX": 0.1259528344745732, "SPINRAZA": 1.4001989675452642, "SPIRONOLACTONE": 1.860144670122444, "STELARA": 0.2063163959383609, "STIVARGA": 1.816252140848781, "SUBOXONE": 1.0338384032023396, "SUTENT": 3.158116476345672, "TAMIFLU": 3.663660307644783, "TASIGNA": 0.3542867532199908, "TICAGRELOR": 32.75609737472881, "TOZINAMERAN": 0.2746003492978336, "TRACLEER": 0.7537655972634897, "TRULICITY": 1.368930202302181, "VAXZEVRIA": 0.1652104612525891, "VIAGRA": 0.4590203773524968, "VICTOZA": 1.0410107067360934, "VOTRIENT": 1.767348412939725, "XARELTO": 7.784190337045868, "XELJANZ": 0.3509699878656671, "XTANDI": 0.3363921540097765, "ZYPREXA": 0.6486337774774833, "null": 1.4291388393533626}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5305.json
index 4f72c17e1bc..99fcae5d4fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5305.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5305.json
@@ -1 +1 @@
-{"AVANDIA": 5.6126197414567605, "AVONEX": 138.07514204204986, "ZOSTAVAX": 3.701553899849742, "null": 1.91342254555837}
\ No newline at end of file
+{"ABACAVIR": 0.1178314425083766, "ADALIMUMAB": 3.3900736521831387, "ADEMPAS": 1.1716882307334695, "AFINITOR": 0.4695767509988247, "AIMOVIG": 0.5332368609329605, "ALEMTUZUMAB": 0.4292944819830435, "ALIGN": 34.12314227259775, "AMINOSALICYLIC": 19.04089314447869, "APIXABAN": 1.1807832160860936, "APREPITANT": 0.7287212854109313, "ARANESP": 0.1445134444226391, "ARAVA": 0.1271675523682304, "ASPARAGINASE": 0.7269906210197504, "AUBAGIO": 0.7821295557843496, "AVAMYS": 9.183514530530108, "AVASTIN": 0.8186769804521411, "AZATHIOPRINE": 1.213694028300002, "BENLYSTA": 0.3069294927130229, "BEVACIZUMAB": 1.0722954833389151, "BEXSERO": 4.235949557450641, "BOSULIF": 0.5455255324147336, "BRAFTOVI": 2.506368910245721, "BRILIQUE": 2.9522318206756446, "BRINTELLIX": 0.519159544873251, "BUDESONIDE": 13.365498338546534, "BUPRENORPHINE": 0.473173415463638, "BUSULFAN": 0.299264080587648, "BYETTA": 0.4776741357606777, "CABOMETYX": 0.5183148165325276, "CAPECITABINE": 0.3661564163812039, "CELLCEPT": 0.2839061832027941, "CHAMPIX": 2.171829360953949, "CICLOSPORIN": 0.6236222183766136, "CIMZIA": 0.5692938853683128, "CLOPIDOGREL": 13.630996166714706, "COMBIVIR": 0.9612196894657528, "COMIRNATY": 0.1674495155385506, "COSENTYX": 2.2187097302302057, "COTELLIC": 1.061451067764344, "CYMBALTA": 0.4050783665619859, "CYTARABINE": 0.9128404653519908, "DEFITELIO": 5.001882453042298, "DEXAMETHASONE": 0.1804152152256148, "DOCETAXEL": 0.3451840771524478, "EFIENT": 2.631405035802383, "ELIQUIS": 6.174741325041334, "ENBREL": 0.630048590576138, "ENOXAPARIN": 5.165601064300165, "ENTRESTO": 0.5419024883955382, "ENTYVIO": 11.78514504555582, "ESBRIET": 0.7067109104088327, "ESOMEPRAZOLE": 0.7185067617611659, "EXJADE": 1.540434822016928, "FASLODEX": 0.3849895162027592, "FENTANYL": 0.2215909876894595, "FIRDAPSE": 0.8109401202475501, "FORSTEO": 0.6620686988483533, "FORXIGA": 0.2258647216816059, "GANCICLOVIR": 0.7042240070207637, "GARDASIL": 0.7092714473309103, "HIZENTRA": 0.501043801990602, "HUMAN": 0.4391366243771502, "HUMIRA": 2.981173264424042, "IBRANCE": 0.8087177187796155, "IBUPROFEN": 1.4293808688639458, "INFANRIX": 6.5645875543084005, "INFLECTRA": 10.782933449898264, "INFLIXIMAB": 6.750640495113327, "INLYTA": 0.9894020688675474, "IPILIMUMAB": 0.6591814064120327, "IRINOTECAN": 1.0474689113305933, "JAKAVI": 0.699440498098584, "JANUVIA": 0.4632111892851195, "JARDIANCE": 0.1917163695522019, "KEPPRA": 0.2015571050791861, "KEYTRUDA": 0.6738701402175358, "LANTUS": 0.1293682368079006, "LEFLUNOMIDE": 1.836431614994067, "LENVIMA": 0.7548583306176697, "LEVOFLOXACIN": 0.2947874009370321, "LIXIANA": 7.79142977927386, "LONSURF": 1.480359402817165, "LYRICA": 0.3160275274499091, "MEKINIST": 0.3321429320029322, "MEPOLIZUMAB": 0.5290305902225526, "MERCAPTOPURINE": 1.114357457383263, "METHOTREXATE": 0.8449040342756435, "MICARDIS": 0.3046359796025898, "MMRVAXPRO": 0.1159306530527859, "NEXAVAR": 2.064970027477269, "NOT": 1.1215838205814244, "NPLATE": 0.3617265418217316, "OCALIVA": 1.6072838304620651, "OFEV": 1.5918846664645, "OLANZAPINE": 0.1705380156040289, "OMALIZUMAB": 0.4719123581688803, "OPDIVO": 0.535322129520954, "OPSUMIT": 0.9129417624232756, "PANTOPRAZOLE": 0.3275797959577921, "PEGASYS": 1.3187895699036685, "PEGINTERFERON": 0.4008956588378587, "PEGINTRON": 0.6224205322694935, "PLAVIX": 7.553392859692189, "PRADAXA": 5.525004349581445, "PREGABALIN": 5.201559829857167, "PREVENAR": 13.067908799921048, "REMICADE": 3.286141358476609, "REMSIMA": 22.429862933830425, "REVATIO": 1.03972088349563, "RINVOQ": 1.270828246974564, "ROACTEMRA": 0.3404952098771805, "ROTARIX": 30.079045065129765, "ROTATEQ": 73.01333734339156, "SAXENDA": 0.9313334765667544, "SHINGRIX": 0.19443939159773, "SILDENAFIL": 1.1003584997697429, "SIMPONI": 1.5490835148286246, "SOLIRIS": 0.3266078452823696, "SPIKEVAX": 0.1828733164971669, "SPRYCEL": 2.255193461066019, "STELARA": 2.528165799610988, "STIVARGA": 1.7589989433266484, "SUTENT": 2.688474710731836, "SYNAGIS": 1.7546792784143266, "TAMIFLU": 1.3082202481397331, "TASIGNA": 0.3598620839162259, "TICAGRELOR": 17.488758055730678, "TOZINAMERAN": 0.4859609652888987, "TRACLEER": 0.523720769660063, "TRELEGY": 0.2214815396918369, "TRULICITY": 0.4288844037365518, "VAXZEVRIA": 0.1495961769518384, "VEDOLIZUMAB": 9.750225039066098, "VELTASSA": 2.690360875403733, "VFEND": 0.7148109256999426, "VIAGRA": 0.711465248331856, "VICTOZA": 0.311499606789598, "VOTRIENT": 1.8723337135998943, "XARELTO": 4.9465574242523065, "XELJANZ": 8.013486725307432, "XOLAIR": 0.2438703636969286, "XTANDI": 0.5563320799410351, "YERVOY": 1.4328174299612333, "ZOSTAVAX": 0.1771249596653093, "ZYPREXA": 0.4364104500650302, "null": 0.8915631064604285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5306.json
index e65103a936e..830cdb8e3ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5306.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5306.json
@@ -1 +1 @@
-{"null": 1.1425222380734628}
\ No newline at end of file
+{"ADENURIC": 84.83115858496569, "JAKAVI": 17.43811155070475, "PEGASYS": 5.25921771551082, "SOLIRIS": 22.530966179682263, "null": 0.9770504967657448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5307.json
index 2ba91d94e9c..2f25fdecba5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5307.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5307.json
@@ -1 +1 @@
-{"null": 1.1777437941946254}
\ No newline at end of file
+{"ABATACEPT": 1.3300031725737895, "ABILIFY": 2.486087707626516, "ACTRAPID": 2.8540721932572395, "ADALIMUMAB": 1.6439083602661868, "ADCIRCA": 2.7382750792997625, "ADENURIC": 3.659162960649169, "AFINITOR": 2.9850527168898173, "ALEMTUZUMAB": 2.803929643877387, "ALIMTA": 2.4102747656145813, "AMIKACIN": 3.892416527627805, "AMINOSALICYLIC": 0.9108279306257788, "ARANESP": 2.70352504566141, "ARAVA": 0.8163360989996056, "ARIPIPRAZOLE": 1.7958186837773151, "AVANDIA": 1.0938518771546426, "AVASTIN": 0.8911298525482229, "BEDAQUILINE": 3.288530461342508, "BEVACIZUMAB": 2.7685056792677663, "BRILIQUE": 4.87215966867938, "CASPOFUNGIN": 10.08771034552078, "CELLCEPT": 1.290739328269884, "CICLOSPORIN": 2.055425274908107, "CIMZIA": 0.1603718398210064, "CLOPIDOGREL": 2.1013771378914043, "COMBIVIR": 1.456046700953546, "COMIRNATY": 0.0732871560350742, "COMTAN": 3.7899886212270286, "COSENTYX": 0.2432455920605318, "CYMBALTA": 0.3084300860571939, "CYTARABINE": 1.025470761923451, "DEXAMETHASONE": 0.4311774543638853, "DOCETAXEL": 1.9503626969157728, "ELIQUIS": 1.2055010215351736, "ENBREL": 0.8345693061587103, "ENOXAPARIN": 3.238744033850485, "ENTRESTO": 3.153285875838852, "ENTYVIO": 0.7051252583990337, "EPOETIN": 9.229948820867802, "ESOMEPRAZOLE": 2.2955874036431307, "EVISTA": 2.513657742006864, "EXFORGE": 0.9767028770894975, "EXJADE": 13.433071136717013, "FASLODEX": 0.6011341138327263, "FENTANYL": 1.2414926226134444, "FORSTEO": 1.0892325036665724, "FULVESTRANT": 4.666604385598965, "GLIVEC": 3.902234984905897, "IBRANCE": 4.237388852170649, "ICLUSIG": 2.0211491628069385, "INCIVO": 2.9023747322074533, "INLYTA": 0.6832653666352347, "INTEGRILIN": 8.535036944170484, "JAKAVI": 10.45915323035157, "JANUMET": 0.5764784030625083, "JANUVIA": 0.6879119858634063, "KEPPRA": 0.7355092817569787, "KEYTRUDA": 0.4589105799585909, "KISQALI": 5.334721197358444, "KYMRIAH": 4.583176079809899, "LANTUS": 0.3963683948965411, "LEMTRADA": 5.630765438191701, "LEVOFLOXACIN": 0.580098900300337, "LYNPARZA": 1.9368182305905424, "LYRICA": 0.5924872132173008, "MEKINIST": 1.3219852532914944, "METFORMIN": 10.207662634458815, "METHOTREXATE": 1.1745887983696646, "MICARDIS": 1.2431212826803535, "MIRCERA": 9.02569323503856, "NALOXONE": 15.3371753997248, "NEULASTA": 1.1883835569147705, "OLANZAPINE": 0.5741097343887953, "OMALIZUMAB": 0.92864900196022, "OPSUMIT": 3.69095576008058, "PEGASYS": 6.866375065843592, "PEGINTERFERON": 1.3631338147087186, "PEGINTRON": 2.933802179443729, "PLAVIX": 3.330424757461006, "RASILEZ": 1.909502518774794, "RIBOCICLIB": 4.957351605025616, "RINVOQ": 2.086892732968893, "RUBRACA": 5.8683464905226925, "RUXOLITINIB": 11.088714795018666, "SOLIRIS": 10.347416795639123, "SOVALDI": 1.749998386933592, "SPIKEVAX": 0.0427763566299417, "STELARA": 0.3954607625842411, "SUTENT": 1.6929717413578418, "TASIGNA": 2.511156387831171, "TOZINAMERAN": 0.1499848637495245, "TRACLEER": 4.185402766710015, "VAXZEVRIA": 0.0241812820832505, "VFEND": 0.8111110664072727, "VOTRIENT": 0.5380745402096573, "XARELTO": 1.3588533997835848, "XELJANZ": 1.055431429792994, "XOLAIR": 0.5475012839104114, "ZIAGEN": 5.334144563589491, "ZOMETA": 6.303005249763632, "ZOSTAVAX": 0.4107651846760251, "ZYPREXA": 1.4204188199739347, "null": 1.286971017683733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5308.json
index 492b29ae9bb..382ddd7ea7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5308.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5308.json
@@ -1 +1 @@
-{"null": 2.219522144485229}
\ No newline at end of file
+{"COMIRNATY": 0.1921794791166601, "EMPAGLIFLOZIN": 65.15206964147711, "FORXIGA": 14.494949779411778, "GONALF": 50.97458676897165, "JAKAVI": 25.09826838520145, "JARDIANCE": 51.851841448044965, "OLANZAPINE": 2.2044986944269884, "ORGALUTRAN": 161.93228765978904, "SPIKEVAX": 0.0927640817368445, "TOZINAMERAN": 0.5024986427025938, "VAXZEVRIA": 0.0726562574069608, "null": 1.2029715515825554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5309.json
index 4c75d4d8c29..e159bdfacaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5309.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5309.json
@@ -1 +1 @@
-{"ELIQUIS": 4.69058633009984, "null": 2.1203067530260964}
\ No newline at end of file
+{"SPIKEVAX": 20.452212841830843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/531.json
index 737c385b299..d56838552ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/531.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/531.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 18.31097742769342, "null": 6.304581907039694}
\ No newline at end of file
+{"null": 0.6781670157280706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5310.json
index 9b13b1b7ae6..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5310.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5310.json
@@ -1 +1 @@
-{"ENTRESTO": 147.5725274569521}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5311.json
index f718fe397d5..77d51fa3fa6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5311.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5311.json
@@ -1 +1 @@
-{"ATRIPLA": 1.257945949934337, "CYMBALTA": 2.3462935595433465, "FORSTEO": 5.085042893945065, "GARDASIL": 2.7332632117912112, "KEPPRA": 3.5784708307580257, "null": 1.070134543493274}
\ No newline at end of file
+{"null": 0.6872665387038563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5312.json
index 7f98d3b787f..2d5af69d38a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5312.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5312.json
@@ -1 +1 @@
-{"GARDASIL": 10.969720467285828}
\ No newline at end of file
+{"NPLATE": 89.06962410391, "null": 2.168809406157068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5313.json
index d6c4b79e745..0df4e030d2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5313.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5313.json
@@ -1 +1 @@
-{"ABILIFY": 3.634086902597341, "ARIXTRA": 32.9126697180814, "CIRCADIN": 34.87244284217698, "CLOPIDOGREL": 1.209410613536076, "DEXAMETHASONE": 3.3701055919535987, "ELIQUIS": 2.578424413578431, "ENOXAPARIN": 11.652234839664258, "KEPPRA": 2.812450387597942, "KEYTRUDA": 2.315381878790771, "MULTAQ": 10.017366773863175, "VFEND": 4.071292260662628, "ZYPREXA": 2.1296587495833457, "null": 2.575762878304656}
\ No newline at end of file
+{"PEGASYS": 8.399116914428886, "SOLIRIS": 36.96601394173455, "null": 0.2518408693848765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5314.json
index 48c404be6a5..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5314.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5314.json
@@ -1 +1 @@
-{"CYMBALTA": 2.68621127695474, "LANTUS": 2.468814694805832, "MMRVAXPRO": 7.823572444570948, "OLANZAPINE": 4.474733129885358, "null": 1.491961324107285}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5315.json
index afde78b8e04..35884908ac6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5315.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5315.json
@@ -1 +1 @@
-{"ABATACEPT": 4.913332455544526, "ADALIMUMAB": 4.761835202629054, "ALISKIREN": 9.275322466282208, "AMBRISENTAN": 1.4996277376490368, "AMBROXOL": 50.21150595409613, "AMLODIPINE": 42.02602056409437, "ANAKINRA": 17.891113336828145, "APREMILAST": 12.221507413573692, "ARAVA": 2.566890644372059, "ATRIPLA": 1.443365931765917, "AUBAGIO": 5.583674539688123, "AVAMYS": 1.429800650578697, "AZILECT": 2.9072966027211464, "BENLYSTA": 1.7290103359270774, "BETAFERON": 2.501567399333673, "BUPIVACAINE": 1.2541954398527904, "CAFFEINE": 30.252681634466477, "CELECOXIB": 1.8031079055830077, "CIMZIA": 1.0227748946724973, "COMIRNATY": 1.0459758335722422, "CONTRAST": 14.405859385082197, "COSENTYX": 1.9083386268668436, "DAPAGLIFLOZIN": 2.3401497710040537, "DULAGLUTIDE": 2.2595781674827027, "DULOXETINE": 1.080654545744259, "ENBREL": 4.759365326516916, "ENTACAPONE": 1.6123497684471388, "ERTAPENEM": 7.119663964112632, "ETANERCEPT": 3.1574895531528955, "EVISTA": 1.693170314287909, "FAMPRIDINE": 6.415137612286107, "FAMPYRA": 13.288268779791428, "FIRDAPSE": 2.464524274103693, "FLUCELVAX": 4.747096413492493, "FORSTEO": 2.8227922562309216, "GILENYA": 2.103802492704021, "HUMALOG": 1.7534562145799808, "HUMIRA": 2.344447401538378, "HYDROCORTISONE": 2.9660269887826183, "IBRANCE": 1.0156283909346573, "ILARIS": 18.187305108247585, "INTELENCE": 2.588487564792472, "LEFLUNOMIDE": 1.5059660281662206, "LEVOFLOXACIN": 12.775584031504165, "NEULASTA": 1.797833338532579, "OCRELIZUMAB": 2.555939187076532, "OMALIZUMAB": 2.0526565769129284, "OPTIMARK": 28.04932357926465, "PLEGRIDY": 2.696607554787472, "RINVOQ": 2.138089171974596, "SHINGRIX": 3.374531468335576, "SPIKEVAX": 1.2523508039338571, "SPINRAZA": 2.969403561972793, "SPIRONOLACTONE": 2.240356063463286, "STALEVO": 1.4422061050273298, "STRIBILD": 1.1222128124008812, "TOZINAMERAN": 1.3302836026435043, "TRULICITY": 1.2523600873255594, "TRUVADA": 1.174078794890619, "TWINRIX": 1.3357570438268416, "VAXZEVRIA": 1.072980111835447, "VIREAD": 1.112329645812363, "XELJANZ": 2.66992969279505, "XOFIGO": 1.4518889534341572}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5316.json
index 12881ae3247..c711963bead 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5316.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5316.json
@@ -1 +1 @@
-{"OCALIVA": 3834.7455166239465}
\ No newline at end of file
+{"ELIQUIS": 34.898158137344055, "null": 1.342347788470703}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5317.json
index 90089f399d5..51616e7b543 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5317.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5317.json
@@ -1 +1 @@
-{"null": 9.527343403928812}
\ No newline at end of file
+{"null": 0.5015340265855428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5318.json
index c812e44b3e2..570f079868c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5318.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5318.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 15.00024975303728, "LAMIVUDINE": 209.13265569696145}
\ No newline at end of file
+{"ADVATE": 23.95071289970571, "ARIXTRA": 75.38139348792014, "BRILIQUE": 11.417540489429, "BUDESONIDE": 0.8040704390172906, "CLOPIDOGREL": 11.325592706980371, "COMIRNATY": 0.1163806498866823, "ELIQUIS": 12.60220178814821, "ENOXAPARIN": 48.86446475296374, "HEMLIBRA": 32.78587640673578, "JAKAVI": 2.372213621056585, "LIXIANA": 6.914985491947554, "MODERNA": 1.1758230610947171, "PLAVIX": 9.281854365421433, "TAMIFLU": 1.8793458866975568, "VAXZEVRIA": 0.1341154631428521, "XARELTO": 16.142705403003053, "null": 3.431057388279628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5319.json
index e0422ef7a81..b86aa0dff3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5319.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5319.json
@@ -1 +1 @@
-{"BIKTARVY": 572.2812317977036}
\ No newline at end of file
+{"null": 0.7775215640317513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/532.json
index 2717ca3680b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/532.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/532.json
@@ -1 +1 @@
-{"ABILIFY": 237.50794988698203, "ARIPIPRAZOLE": 447.9641777227113, "OLANZAPINE": 3.4954684399884868}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5320.json
index 452e4b93a14..354943c8b9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5320.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5320.json
@@ -1 +1 @@
-{"DARZALEX": 203.9453988685196}
\ No newline at end of file
+{"COMIRNATY": 0.1947411304700374, "ELIQUIS": 3.917147040616148, "VAXZEVRIA": 0.9248097401833828, "VIAGRA": 56.93989320388568, "null": 0.9811402250931696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5321.json
index 732b6c7a19c..27c14958442 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5321.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5321.json
@@ -1 +1 @@
-{"DARZALEX": 85.2101406936284, "null": 1.1577430836966396}
\ No newline at end of file
+{"AFINITOR": 1.66422002469376, "ALIMTA": 18.18047000409302, "ASPARAGINASE": 39.7439864866309, "AUTOLOGOUS": 900.225238050385, "AVASTIN": 6.273187028564526, "AZACITIDINE": 45.96069004427152, "BEVACIZUMAB": 25.02103812619014, "BORTEZOMIB": 5.014086440832481, "BUSULFAN": 1.9349642015750907, "CAELYX": 12.74634902097489, "CAPECITABINE": 14.95689403558011, "CARFILZOMIB": 6.9023314875150845, "CARMUSTINE": 91.91135750287236, "CELLCEPT": 1.940424856677045, "CETUXIMAB": 22.83093732451928, "CICLOSPORIN": 0.711897922632678, "CLADRIBINE": 13.191364244338963, "CYTARABINE": 8.532628794068346, "DARATUMUMAB": 27.306766249685985, "DARZALEX": 6.67487551328717, "DEXAMETHASONE": 4.171035044974905, "DOCETAXEL": 16.659864057754387, "DOXORUBICIN": 7.817870414904575, "FASLODEX": 1.3366844021967188, "FULVESTRANT": 9.397932207284091, "GLIVEC": 7.928366869414983, "HYCAMTIN": 19.74903657799025, "IBRANCE": 3.3403637038813287, "ICLUSIG": 12.952161655373692, "IMATINIB": 20.43860401847871, "IRINOTECAN": 32.63859910568032, "JAKAVI": 3.141661215605704, "JEVTANA": 10.568738710373212, "KEYTRUDA": 1.9765817904174887, "KISQALI": 9.52389482859843, "LONSURF": 7.130697356303676, "LOPINAVIR": 16.997252055293124, "LUTATHERA": 30.436555517539382, "LUTETIUM": 53.23100045612008, "LYNPARZA": 20.220523194314836, "METHOTREXATE": 2.693978720192474, "NEXAVAR": 1.7594670637644805, "NILOTINIB": 26.942674821013792, "OBINUTUZUMAB": 12.510331163226136, "OLAPARIB": 31.74342982354335, "PACLITAXEL": 15.127491562013253, "PEMBROLIZUMAB": 4.317281802221969, "PEMETREXED": 59.72475605556156, "RIBOCICLIB": 19.478325362592496, "RITUXIMAB": 7.211051079679289, "RUBRACA": 4.10209729463261, "SORAFENIB": 11.741519357162655, "SPRYCEL": 4.18158776538611, "SUTENT": 2.266795220152406, "TAGRISSO": 2.965636279316429, "TASIGNA": 5.448402478505148, "TEMODAL": 6.993518151542569, "TEMOZOLOMIDE": 55.01334121756218, "THIOTEPA": 34.0783825233434, "TOPOTECAN": 14.682500968407506, "TRODELVY": 8.106610741968414, "VECTIBIX": 20.76880639419742, "VENETOCLAX": 30.873930476153586, "XOFIGO": 21.629561732648952, "YONDELIS": 27.102429169140475, "null": 0.4349319569256405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5322.json
index 02855532f02..de1bb795f9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5322.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5322.json
@@ -1 +1 @@
-{"ANAKINRA": 4518.732904412501}
\ No newline at end of file
+{"ADALIMUMAB": 0.3669813931487999, "ADENURIC": 1.808048941115118, "ADVATE": 2.94461079396561, "AFINITOR": 0.6663712624084652, "ALEMTUZUMAB": 1.6185120796664896, "ALIMTA": 0.3824780374138203, "APIXABAN": 0.902831829691453, "APROVEL": 0.915438635789537, "ARANESP": 0.2299676126641048, "ARAVA": 0.0308303405296861, "ARIXTRA": 6.903668053939697, "ASPARAGINASE": 0.5777048531122678, "ATAZANAVIR": 2.486970427047161, "ATRIPLA": 0.6899051079720091, "AVASTIN": 1.708245881007047, "AVELUMAB": 2.679155157518853, "BARACLUDE": 1.4511480179776202, "BASILIXIMAB": 4.774283069027482, "BENLYSTA": 0.3796678574450763, "BETMIGA": 1.814884890044833, "BEVACIZUMAB": 1.6376819752259897, "BRILIQUE": 16.443115439202668, "BUDESONIDE": 0.1803321169855012, "BUSILVEX": 4.311988840851732, "BUSULFAN": 3.244451209741445, "BYETTA": 0.6276073122909538, "CABAZITAXEL": 12.193773802825952, "CABOMETYX": 0.6338260898288814, "CANCIDAS": 2.5261554531428003, "CELLCEPT": 1.3756742518515654, "CHAMPIX": 0.7319142216888084, 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"SILDENAFIL": 0.6700894928242823, "SOLIRIS": 2.5780001041469798, "SOVALDI": 0.7728800288552116, "SPIKEVAX": 0.234951821793203, "SPINRAZA": 1.8909073419988127, "SPIRONOLACTONE": 2.500963812934925, "SPRYCEL": 0.3410793697458091, "STELARA": 0.4221366728319885, "STIVARGA": 1.7205693085373146, "STRIBILD": 0.4681831931376107, "SUBOXONE": 0.2152407167615252, "SUTENT": 2.047454739302634, "TAMIFLU": 2.1216630045715763, "TASIGNA": 0.3452036779903541, "TELMISARTAN": 1.4897959211284113, "TICAGRELOR": 9.169292620862317, "TOPOTECAN": 2.766400653094257, "TORISEL": 1.3667753045856026, "TOVIAZ": 0.9406308405132264, "TOZINAMERAN": 0.2246729718373388, "TRUVADA": 0.3821936268001927, "VAXZEVRIA": 0.1404416770897685, "VFEND": 0.6072986032305933, "VIAGRA": 1.1621223364077533, "VIREAD": 0.7482114250680251, "VORICONAZOLE": 0.5559844082436098, "VOTRIENT": 1.3571115331720502, "XARELTO": 19.47667888848008, "XELJANZ": 0.1323284608481271, "XOFIGO": 1.8004709053470884, "XOLAIR": 0.2290577975467545, "XTANDI": 2.0918382320871345, "ZOSTAVAX": 0.8270562839947686, "ZYPREXA": 0.7129961250196182, "null": 1.545879291652096}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5323.json
index d842ec04f69..30d5d76ebba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5323.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5323.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 21.62742227465071, "CICLOSPORIN": 4.361474125001556, "IBRANCE": 8.704475938106404, "LEMTRADA": 38.051814173734186}
\ No newline at end of file
+{"CLOPIDOGREL": 15.65866819502525, "ELIQUIS": 9.053311787647974, "LENVIMA": 47.64103992779931, "NEXAVAR": 55.40618228772155, "PLAVIX": 8.632726510367853, "null": 0.6706380298945842}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5324.json
index 828b0c673b4..70854778cd2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5324.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5324.json
@@ -1 +1 @@
-{"ABATACEPT": 6.667587432343806, "ADALIMUMAB": 1.8612997377292664, "ARIPIPRAZOLE": 5.406511959835667, "AUBAGIO": 4.333626423606355, "ENBREL": 4.331263327736288, "EXJADE": 5.627645872578109, "IBRANCE": 2.884459912449413, "JAKAVI": 4.315617139061603, "MEPOLIZUMAB": 3.7617063447774512, "METHOTREXATE": 3.6640855520020255, "PEGASYS": 1.163148190219845, "PEGINTERFERON": 5.066591548712127, "RUXOLITINIB": 22.491540704952385, "ZOSTAVAX": 1.7848585696247663}
\ No newline at end of file
+{"ARAVA": 1.845521055167178, "EXJADE": 47.9677763047148, "PEGASYS": 8.25056931707855, "null": 0.7501957403783551}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5325.json
index 9e0de84c241..56fece381a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5325.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5325.json
@@ -1 +1 @@
-{"LEMTRADA": 200.10094088166096}
\ No newline at end of file
+{"null": 2.648162525123761}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5326.json
index dd8cf1f2252..022546ef0f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5326.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5326.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 86.31492287084673, "IBRANCE": 6.400424103006786, "OMALIZUMAB": 35.516110586954184}
\ No newline at end of file
+{"APIDRA": 4.39895567956903, "ARANESP": 117.29989186112634, "AZATHIOPRINE": 6.79388428299945, "BIKTARVY": 10.926470096349258, "CELLCEPT": 5.138892724575992, "CICLOSPORIN": 17.6719298486061, "CUBICIN": 10.059418181292155, "ELIQUIS": 1.0111872373109394, "LANTUS": 2.729121913640665, "OPSUMIT": 4.523628767791503, "PEGINTRON": 1.4854075357112873, "SOLIRIS": 5.911820949467304, "SPIKEVAX": 0.0909871084118948, "null": 1.0867728295840235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5327.json
index 925984eb1a5..5bf40364f3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5327.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5327.json
@@ -1 +1 @@
-{"null": 1.0379271266124754}
\ No newline at end of file
+{"null": 2.7190485237635444}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5328.json
index c42acc8783d..c57936b28a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5328.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5328.json
@@ -1 +1 @@
-{"null": 1.324753522196647}
\ No newline at end of file
+{"ARAVA": 15.32828935423587, "null": 0.5447738916505026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5329.json
index 2697b21aeb2..a713fc458f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5329.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5329.json
@@ -1 +1 @@
-{"COMIRNATY": 1.531093835014037}
\ No newline at end of file
+{"AMIKACIN": 13.72693929803472, "ANAKINRA": 3.116900988685394, "ANIDULAFUNGIN": 68.80844849758704, "ARIPIPRAZOLE": 1.9560532534639063, "AZACITIDINE": 9.609600102688969, "BRIDION": 7.327077201472442, "BUPIVACAINE": 6.405113741447217, "CELLCEPT": 2.081443448132596, "CICLOSPORIN": 1.940587113304664, "CLOPIDOGREL": 4.740743947282608, "COMIRNATY": 0.0335926183846158, "CYTARABINE": 2.787054549417832, "DEXAMETHASONE": 4.515529056009427, "DEXMEDETOMIDINE": 32.19564129964526, "ELIQUIS": 0.6662739431342499, "ENOXAPARIN": 13.961267249533632, "FENTANYL": 10.61061892729434, "GANCICLOVIR": 6.7532442981957965, "GLUCAGON": 25.63312861873641, "IBUPROFEN": 10.204744273461664, "JARDIANCE": 0.6765749444043893, "KYMRIAH": 3.1639243104934165, "LEVETIRACETAM": 5.880561818582035, "LEVOFLOXACIN": 4.81228916830265, "MIDAZOLAM": 18.68865778039921, "OLANZAPINE": 2.622588426835528, "OPSUMIT": 1.8322395255830428, "SILDENAFIL": 13.950686601811007, "SUFENTANIL": 18.45473884285001, "TRACLEER": 2.7061258934387142, "VAXZEVRIA": 0.0745400515951374, "null": 2.166046066604657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/533.json
index b28b8fa1d6e..6e8118aa9fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/533.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/533.json
@@ -1 +1 @@
-{"null": 3.6736587314690303}
\ No newline at end of file
+{"PEMETREXED": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5330.json
index e72ce84edca..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5330.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5330.json
@@ -1 +1 @@
-{"PEGASYS": 5.523378368757425, "PEGINTRON": 13.961157350823347, "TELMISARTAN": 120.48405403877672, "null": 1.0808021790561764}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5331.json
index e39e635686e..596119666bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5331.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5331.json
@@ -1 +1 @@
-{"MIDAZOLAM": 226.59276516001088, "null": 1.0875014698081733}
\ No newline at end of file
+{"null": 1.436254850849268}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5332.json
index cada8b79a91..51a3d619e05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5332.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5332.json
@@ -1 +1 @@
-{"AUBAGIO": 1.9272208417402683, "CLOPIDOGREL": 1.592643251116262, "COMIRNATY": 2.4788084943555684, "COVID19": 1.564157371348475, "GARDASIL": 3.207761190666808, "SHINGRIX": 1.37728859559373, "TOZINAMERAN": 1.1935894875267363, "VAXZEVRIA": 1.9649630109023637}
\ No newline at end of file
+{"PEGASYS": 20.63941900416405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5333.json
index 3227b8ae16b..9152205e8d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5333.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5333.json
@@ -1 +1 @@
-{"COMBIVIR": 3.015751250058257, "COMIRNATY": 1.730155991294632, "COVID19": 1.139803094974798, "EYLEA": 1.968057305955301, "FENTANYL": 1.4813035066672902, "FORSTEO": 1.3219872042430267, "GARDASIL": 5.566736809569423, "SHINGRIX": 3.3504338913242737, "SPIKEVAX": 1.1630944682016515, "TOZINAMERAN": 2.479415176496815, "TWINRIX": 4.35447158336323, "VAXZEVRIA": 1.4776182157590834}
\ No newline at end of file
+{"LAMIVUDINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5334.json
index fecdc8f0daf..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5334.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5334.json
@@ -1 +1 @@
-{"ABILIFY": 2.954844296794644, "AERIUS": 2.451858359423866, "ARIPIPRAZOLE": 4.223109665906919, "BIKTARVY": 1.285814741566888, "BOTULINUM": 3.187024307882343, "BRINTELLIX": 3.729614605955202, "BRIVIACT": 6.038663098525994, "CELECOXIB": 4.028828927031591, "CHAMPIX": 24.553460101514187, "CYMBALTA": 1.9752559891226529, "DULOXETINE": 1.896370670365924, "ELLAONE": 3.743010773041569, "FENTANYL": 1.207819939782454, "FORSTEO": 1.196919516868291, "FYCOMPA": 12.627323155305202, "KAFTRIO": 7.659714375123392, "KEPPRA": 5.5496277945870505, "LATUDA": 4.688870847023732, "LEMTRADA": 2.3721595954009, "LEVETIRACETAM": 5.388692778598893, "LEVODOPA": 4.0301309454851015, "LYRICA": 1.5482745246726428, "MMRVAXPRO": 1.4961392408377825, "OLANZAPINE": 2.074365282628174, "PANTOPRAZOLE": 2.5556111218383437, "PEGASYS": 3.9170019104844354, "PEGINTERFERON": 3.1912271811445683, "PEGINTRON": 2.5368567787863925, "PLEGRIDY": 1.5539946921195564, "PREVENAR": 6.950834823899874, "RIBAVIRIN": 1.6804812862219265, "RISPERIDONE": 3.062818842060969, "ROTATEQ": 1.1765008717129073, "SAXENDA": 1.7867187072904924, "SUBOXONE": 1.647756650327464, "TAMIFLU": 1.8689087426209232, "TRIUMEQ": 3.3596108684714348, "VARENICLINE": 7.970782773944391, "VIMPAT": 2.6923124794718207, "XYREM": 2.380997367637278, "null": 1.800817010737623}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5335.json
index a1024cd761a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5335.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5335.json
@@ -1 +1 @@
-{"ABILIFY": 1.9236041063080032, "BRINTELLIX": 2.4931073899653287, "BRIVARACETAM": 8.259207953150085, "BRIVIACT": 12.34908179675857, "BUPRENORPHINE": 1.9745928417945728, "CHAMPIX": 20.842103167413807, "CYMBALTA": 23.31086633979196, "DAKLINZA": 3.988207913442861, "DULOXETINE": 1.5772719405965965, "ELLAONE": 19.94721924100916, "ESMYA": 6.707144644639451, "EVRA": 2.8882909445655454, "FAMPYRA": 1.595993989071192, "GARDASIL": 1.900190200592024, "INCIVO": 3.250206722718535, "KAFTRIO": 6.109029478646402, "KEPPRA": 8.014207195521426, "LATUDA": 6.207860266090219, "LEVETIRACETAM": 3.505062928250133, "NUCALA": 1.3760972303522303, "ORKAMBI": 3.379896707076513, "PEGASYS": 3.773605450971736, "PEGINTERFERON": 1.6086572127665886, "PEGINTRON": 3.3228463373999326, "PLEGRIDY": 1.3476744105070952, "RIBAVIRIN": 1.1014466963652907, "RISPERIDONE": 3.8223233951197466, "RYEQO": 15.989526844285349, "SOVALDI": 2.400183233757752, "TAMIFLU": 1.3037144133630654, "VARENICLINE": 15.749139610367603, "VIMPAT": 2.494658604364797, "null": 1.4598619344686643}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5336.json
index 98fb75f9b20..0d49d3f7af6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5336.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5336.json
@@ -1 +1 @@
-{"AMIKACIN": 234.4438383409893}
\ No newline at end of file
+{"EXJADE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5337.json
index 755e503388c..73519ff4973 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5337.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5337.json
@@ -1 +1 @@
-{"CHAMPIX": 25.744439973842464, "CYMBALTA": 2.7746362247199667, "KEPPRA": 8.47177729143926, "null": 2.234088760968957}
\ No newline at end of file
+{"ADENURIC": 17.507165854840945, "ALISKIREN": 19.845709258691716, "ARANESP": 46.34517430832325, "BEVACIZUMAB": 3.67771627201035, "CELLCEPT": 2.375240766021732, "CLOPIDOGREL": 4.665717888877805, "COMIRNATY": 0.0229311364895504, "CYTARABINE": 21.192435046281325, "ELIQUIS": 2.81667108255038, "IBRANCE": 1.499215669249179, "JAKAVI": 13.85744780869198, "JARDIANCE": 1.1116202145613927, "KEYTRUDA": 4.161181808450198, "MEPOLIZUMAB": 4.497561333995736, "NEULASTA": 8.205515259717526, "OLAPARIB": 28.29443893371044, "PEGASYS": 4.651654299375388, "PEGINTRON": 2.26491664928827, "RIBAVIRIN": 5.890354563154924, "RUXOLITINIB": 20.69857129316561, "SOLIRIS": 23.822083738152024, "SUTENT": 0.597540410685349, "XOFIGO": 11.864105421691882, "null": 0.573917768221388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5338.json
index 25f68494b01..f2bf4132827 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5338.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5338.json
@@ -1 +1 @@
-{"null": 4.1423793880704975}
\ No newline at end of file
+{"ABACAVIR": 0.3558066246817389, "ABATACEPT": 0.2906740646718311, "ABILIFY": 0.7073421714783709, "ABRAXANE": 1.8912463906037889, "ACE": 6.229015300163077, "ACTRAPID": 0.5369537788302458, "ADALIMUMAB": 0.3586343945979637, "ADCIRCA": 1.8448923266996988, "ADEMPAS": 2.208148326650264, "ADENURIC": 0.7794630661154867, "AFINITOR": 2.869058070268579, "AIMOVIG": 0.0683469831426879, "ALEMTUZUMAB": 1.0118347562595418, "ALIMTA": 2.6613181790944767, "AMBRISENTAN": 0.792396232872508, "AMIKACIN": 0.8835151972761469, "AMINOSALICYLIC": 2.714781668803715, "ANAGRELIDE": 11.317748609915052, "ANAKINRA": 2.9179190553092926, "ANGIOX": 5.936204469293225, "APIXABAN": 0.8921615603963872, "APREMILAST": 0.6804209813263294, "ARANESP": 9.275835483106544, "ARAVA": 0.351305754730115, "ARIPIPRAZOLE": 1.0766294888887216, "ARIXTRA": 3.8825875924515976, "ASPARAGINASE": 0.621146991212888, "ATAZANAVIR": 0.9517203978350056, "ATEZOLIZUMAB": 2.098973313081164, "ATRIPLA": 0.0145829662726504, "AUBAGIO": 0.2372303387432408, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5339.json
index c301ac4fbc9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5339.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5339.json
@@ -1 +1 @@
-{"BORTEZOMIB": 284.2395129934279}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/534.json
index aff3d6ef166..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/534.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/534.json
@@ -1 +1 @@
-{"ABILIFY": 3.860186491583365, "ARIPIPRAZOLE": 15.020719432282585, "IRON": 41.64382396910717, "OLANZAPINE": 19.266132377911028, "ZYPADHERA": 11.793153247741134, "ZYPREXA": 4.8880740623079, "null": 6.679057747235033}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5340.json
index 9543a34eebd..b5e41111b42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5340.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5340.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 18.22255925453364, "COVID19": 1.8227696363050048, "LANTUS": 4.977455456457704, "TOZINAMERAN": 2.347396016751878}
\ No newline at end of file
+{"ARANESP": 15.464113856854864, "CELLCEPT": 2.1910356028419717, "COMIRNATY": 0.1584056971882866, "CYMBALTA": 13.605723454803243, "ELIQUIS": 0.6502783520742389, "EMPAGLIFLOZIN": 50.79588195266864, "ENTRESTO": 3.014614820253325, "FORXIGA": 6.8805500546271885, "HUMALOG": 0.9938997143524884, "JAKAVI": 10.487344168427972, "JANUMET": 2.546609037372523, "JARDIANCE": 12.607004109869685, "KEYTRUDA": 1.5223486262093362, "METHOTREXATE": 2.528897831414537, "MIRCERA": 35.968062055525465, "NEXAVAR": 1.4470658222631168, "SUTENT": 0.5512022599589947, "TOZINAMERAN": 0.4806434464901744, "VAXZEVRIA": 0.0846484077101299, "VOTRIENT": 4.348488230098944, "ZYPREXA": 1.3004748654103646, "null": 0.8331326412319923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5341.json
index 8e1da12e16c..cbb83fc9ae2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5341.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5341.json
@@ -1 +1 @@
-{"null": 2.863469777983985}
\ No newline at end of file
+{"SPIKEVAX": 16.975956652032924}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5342.json
index 3d96d171b0a..b8015efadb4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5342.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5342.json
@@ -1 +1 @@
-{"ARAVA": 2.9813486577318904, "COMIRNATY": 1.1197687506241027}
\ No newline at end of file
+{"ADENURIC": 552.9062051057653, "null": 0.4905699579185362}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5343.json
index e6e05d24184..6862367606c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5343.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5343.json
@@ -1 +1 @@
-{"METHOTREXATE": 66.38308767528781}
\ No newline at end of file
+{"null": 0.4549782352129193}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5344.json
index fbd283531d8..7c3c7689d72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5344.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5344.json
@@ -1 +1 @@
-{"BRINTELLIX": 6.370097728739999, "COVID19": 3.0262720549873903, "CYMBALTA": 2.0720302274388755, "GARDASIL": 4.564294642739241, "PEGASYS": 1.65950283295348, "TOZINAMERAN": 4.755861875191933}
\ No newline at end of file
+{"PRIVIGEN": 53.52160665306746, "SOLIRIS": 371.0713233141034, "null": 0.5332589627468022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5345.json
index 632abfa9ff0..aeffa9d55ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5345.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5345.json
@@ -1 +1 @@
-{"ASPARAGINASE": 65.92066238831329, "AVAMYS": 16.659412148175193, "INFANRIX": 65.78443483083953, "KEPPRA": 6.633354691234914, "null": 3.263020816914346}
\ No newline at end of file
+{"AFINITOR": 0.5566896448097527, "ALOXI": 91.04718887035745, "ARANESP": 1.5790133462473943, "AZATHIOPRINE": 5.226711236548641, "CELLCEPT": 3.054183651322782, "CICLOSPORIN": 5.093794443016761, "COMBIVIR": 1.8463751632047836, "COMIRNATY": 0.069060220940532, "CRIXIVAN": 5.218116735602054, "DARZALEX": 2.3652028723529845, "EXJADE": 4.469273073500288, "EXVIERA": 6.469178084977756, "FASTURTEC": 127.16543489514792, "FLEBOGAMMA": 5.9061059658649, "HARVONI": 2.5010698339926307, "HUMAN": 41.10746564468607, "JAKAVI": 4.442414071943248, "KEPPRA": 0.4894327287326664, "KEYTRUDA": 0.2870425592381689, "KIOVIG": 40.068465592741504, "KYPROLIS": 6.098184267762944, "LEVOFLOXACIN": 0.8734235439326126, "MYCAMINE": 38.06759928559801, "NPLATE": 2.371862999466807, "PEGASYS": 1.4646571689628998, "PEGINTERFERON": 2.2511420796755077, "PEGINTRON": 2.482441073657569, "PLAVIX": 0.5783143396566394, "PRIVIGEN": 61.13158230321904, "RASBURICASE": 138.26491241134434, "RIBAVIRIN": 15.752057155528544, "ROACTEMRA": 1.048097016539875, "SOLIRIS": 192.63669030211705, "SPIKEVAX": 0.0692570725157918, "SUTENT": 0.6593667720865931, "TAMIFLU": 1.055319644289158, "TOZINAMERAN": 0.1245009499768454, "VAXZEVRIA": 0.0478694322355045, "VENETOCLAX": 6.913563576108045, "null": 0.943069417765292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5346.json
index b9128ee735e..3da1068268b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5346.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5346.json
@@ -1 +1 @@
-{"ABILIFY": 1.8375099809934772, "ALISKIREN": 50.13723904052972, "ASPARAGINASE": 2.0277978531552314, "AUBAGIO": 2.0892280592953254, "BUPIVACAINE": 11.146037610263733, "CARBIDOPA": 11.06582596302105, "CELLCEPT": 1.0991462473239753, "COSENTYX": 1.062386332015116, "ENTACAPONE": 29.35575909122322, "ESOMEPRAZOLE": 4.934519683934377, "FAMPYRA": 29.0962909989145, "FENTANYL": 1.2532768020826168, "FIRDAPSE": 3.8288868154505455, "GARDASIL": 1.8916955005770093, "IBUPROFEN": 1.2250652895262468, "LEMTRADA": 2.301005739984688, "LEVETIRACETAM": 3.2781991690739973, "LEVODOPA": 10.732357297884976, "OLANZAPINE": 1.1881202988404242, "OPTIMARK": 8.128637198305313, "PLEGRIDY": 6.750803214393726, "SHINGRIX": 1.028669083292663, "SIFROL": 4.883028722099444, "SPINRAZA": 19.01756437435784, "SPIRONOLACTONE": 9.763492882981032, "STALEVO": 5.006339917569944, "TASIGNA": 1.6089693685039252, "TWINRIX": 2.4558099113729592, "null": 1.2435911877173098}
\ No newline at end of file
+{"ABACAVIR": 0.478231736109721, "AFINITOR": 0.4418431637462418, "ALEMTUZUMAB": 2.241506975047836, "ALIMTA": 2.222335508831179, "ARANESP": 0.524149271418205, "ARAVA": 0.0586513327326106, "ATAZANAVIR": 4.044724005953814, "ATRIPLA": 0.1324046085767914, "AVANDIA": 0.411519024261109, "AVASTIN": 2.0191721922886, "BOCEPREVIR": 11.56926518439374, "BUSULFAN": 1.748125770440221, "CARFILZOMIB": 5.752385116305821, "CELLCEPT": 3.067169650168879, "CICLOSPORIN": 2.822317869168053, "CLOPIDOGREL": 0.8755867276427768, "COAPROVEL": 2.272224694746178, "COMBIVIR": 7.7129316927656975, "COMIRNATY": 0.0712219554423836, "CRIXIVAN": 12.136848413733292, "DEXAMETHASONE": 0.480750254315783, "EBIXA": 6.088372109860061, "ELIQUIS": 0.20343871069914, "ENTYVIO": 1.0705947521861574, "ESOMEPRAZOLE": 2.863958411436394, "EXJADE": 1.9704626654973805, "FASLODEX": 1.207603305327101, "FASTURTEC": 158.64867509702987, "HARVONI": 1.7527049071074634, "HUMAN": 34.21681370734074, "IBRANCE": 0.2318845658255098, "INCIVO": 2.962167094576873, "INTERFERON": 11.715555197298055, "INTRONA": 18.447631254296628, "IPILIMUMAB": 1.3119796003081556, "ISENTRESS": 2.8610902433984724, "JAKAVI": 1.3431733606432787, "JANUMET": 0.7191661154146572, "JARDIANCE": 0.4067994378412256, "KEPPRA": 0.5511910836795874, "KEYTRUDA": 1.3610236610187327, "KIOVIG": 15.936833509753832, "KYPROLIS": 9.987702033127498, "LANTUS": 0.1650857341968914, "LEMTRADA": 5.45656695782342, "LEVOFLOXACIN": 1.4302962319988175, "METHOTREXATE": 0.5032476510809604, "MIDAZOLAM": 1.2984317830866838, "MYCAMINE": 18.52614058850419, "MYCOPHENOLATE": 2.3839014661997275, "NEXAVAR": 0.4086522550832467, "NORVIR": 2.356238692080797, "NOT": 2.4442927886467456, "NOVONORM": 9.242107666145804, "NPLATE": 3.15142464965738, "OPDIVO": 1.1489801652735945, "PEGASYS": 8.697255856136703, "PEGINTERFERON": 7.266141775465452, "PEGINTRON": 7.391910526407071, "PLAVIX": 1.1092494787808298, "PRIVIGEN": 31.198500925407465, "RASBURICASE": 154.15323944948963, "REBETOL": 32.980256969230524, "RIBAVIRIN": 16.574781536664425, "SOLIRIS": 4.997996780678127, "SOVALDI": 12.313385417004216, "SPIKEVAX": 0.0533878021825537, "STELARA": 0.4934047515673046, "SUTENT": 0.4804911188102647, "TAMIFLU": 1.561077195153156, "TASIGNA": 0.8110628800747275, "TEMODAL": 3.464307995711492, "TOZINAMERAN": 0.1262684401516854, "TRUVADA": 0.1183827723893253, "VAXZEVRIA": 0.0472172903060716, "VENETOCLAX": 3.1415786739025995, "XELJANZ": 0.2153856113956972, "null": 1.684401358256169}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5347.json
index e9f43d4f4a4..4c622802e4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5347.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5347.json
@@ -1 +1 @@
-{"RILUTEK": 1354.1392518161315, "TOZINAMERAN": 2.073115216548373, "VAXZEVRIA": 1.475581521985156}
\ No newline at end of file
+{"null": 1.1699170674426764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5348.json
index 77cb7f8e8c3..30dee5318c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5348.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5348.json
@@ -1 +1 @@
-{"null": 1.6822364083208643}
\ No newline at end of file
+{"AVASTIN": 4.549800460976415, "CARFILZOMIB": 21.99312525787101, "CELLCEPT": 11.000863947247426, "CICLOSPORIN": 28.31427628623721, "CLOPIDOGREL": 1.5247871967677262, "COMIRNATY": 0.0303101601945918, "KYPROLIS": 31.87407445538449, "RAPAMUNE": 82.4760154314649, "SOLIRIS": 58.00253211012946, "SUTENT": 1.140072231040473, "null": 1.429336455969083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5349.json
index ac6e53c9fc9..ad7eae3500e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5349.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5349.json
@@ -1 +1 @@
-{"COVID19": 3.784728824037096}
\ No newline at end of file
+{"BRILIQUE": 9.200692216419434, "CETROTIDE": 166.83489865666, "CLOPIDOGREL": 4.9243698637285584, "COMIRNATY": 0.0538808516706832, "ELIQUIS": 6.182824944571112, "ENOXAPARIN": 29.41206617604368, "GONALF": 74.82980670656231, "NEXAVAR": 2.38478140710606, "NOVOSEVEN": 31.41375430989804, "PLAVIX": 6.823704548064068, "SILDENAFIL": 11.028878799817454, "SUTENT": 1.107216456145152, "VAXZEVRIA": 0.0917018235475291, "null": 2.477075323404153}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/535.json
index 7ff6c04841a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/535.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/535.json
@@ -1 +1 @@
-{"OLANZAPINE": 8.959125441339296, "null": 4.741994668750362}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5350.json
index 8c5207b3efe..e8355898be4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5350.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5350.json
@@ -1 +1 @@
-{"ADVATE": 34.60356212098903, "AFINITOR": 1.0883091863935253, "ALISKIREN": 10.81951499422057, "APIXABAN": 3.091924044141797, "AVASTIN": 1.6318689879871375, "BRILIQUE": 2.849301697700111, "CLOPIDOGREL": 6.025420022427461, "CYTARABINE": 1.2412548160470522, "DEFITELIO": 26.962058141958032, "ELIQUIS": 7.591971987547864, "ENOXAPARIN": 4.82537450522635, "EXJADE": 1.07375721962602, "FENTANYL": 1.3566851850784891, "HEMLIBRA": 45.31209499041631, "IBUPROFEN": 1.226898020498966, "LIXIANA": 15.50421722005541, "NEXAVAR": 3.678798995538519, "NPLATE": 14.5808009714183, "PEGASYS": 1.860619294592303, "PEGINTRON": 1.381623748365982, "PLAVIX": 8.651168684259495, "STIVARGA": 1.8732821183274937, "SUTENT": 4.48645789071857, "XARELTO": 10.192896405835326, "null": 1.1910576486326243}
\ No newline at end of file
+{"ADALIMUMAB": 0.2742355515509195, "ALEMTUZUMAB": 18.455838715641203, "ANAKINRA": 17.3576464737494, "ASPARAGINASE": 1.9147054006094204, "AZACITIDINE": 14.078457478158864, "AZATHIOPRINE": 5.349174913109832, "BORTEZOMIB": 3.8214682307629415, "BUSULFAN": 12.725961671727896, "CABOMETYX": 2.0354791878228404, "CANCIDAS": 5.224009958049547, "CASPOFUNGIN": 7.296665380041955, "CELLCEPT": 6.764452102797425, "CICLOSPORIN": 16.20052419836649, "COMIRNATY": 0.1597106613864351, "CYTARABINE": 9.633523333615232, "DABRAFENIB": 14.5978623926523, "DEXAMETHASONE": 6.621375900074577, "DOXORUBICIN": 3.5056478274243608, "EPIVIR": 5.60846677252474, "FILGRASTIM": 12.59214449028324, "GANCICLOVIR": 19.533609795889223, "INCIVO": 1.913153524657706, "INFLIXIMAB": 7.166093809176325, "IPILIMUMAB": 11.841191342117146, "JAKAVI": 1.2833138450280708, "KEPPRA": 1.2137211476886125, "KEYTRUDA": 8.293215613179738, "KYMRIAH": 39.15127894587606, "LEMTRADA": 2.4597961614117203, "LEVETIRACETAM": 3.036925348731608, "LEVOFLOXACIN": 1.9714425691554889, "MEKINIST": 10.826520826364264, "MELPHALAN": 22.19933142471585, "MERCAPTOPURINE": 15.902933191788792, "METHOTREXATE": 3.398019345055091, "MYCOPHENOLATE": 7.553402835945369, "OPDIVO": 16.57668238767877, "PEGASYS": 0.3793872396181976, "PEMBROLIZUMAB": 5.397031303734889, "RITUXIMAB": 1.6345808428760016, "ROACTEMRA": 5.818354038999269, "ROTATEQ": 2.430479498462464, "SOLIRIS": 1.786123943955551, "SPIKEVAX": 0.093190100699245, "TISAGENLECLEUCEL": 61.20934212873309, "TOCILIZUMAB": 25.402921322524023, "TOZINAMERAN": 0.2672190518610584, "VAXZEVRIA": 0.13245584516269, "YESCARTA": 29.78905983703002, "null": 0.7682851111028319}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5351.json
index 3aeed83f29b..cfbbc7f05d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5351.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5351.json
@@ -1 +1 @@
-{"EFAVIRENZ": 28.339872014752263, "GARDASIL": 2.559722159869604, "PEGASYS": 2.0821070060505384, "SUTENT": 43.57623112608271, "null": 1.1475644802128255}
\ No newline at end of file
+{"null": 0.3944676594233216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5352.json
index 195e2555de7..2441e7feeaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5352.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5352.json
@@ -1 +1 @@
-{"AFINITOR": 1.581334555485879, "BETMIGA": 3.7193403503664033, "CHAMPIX": 2.3675601942732225, "ENTRESTO": 1.4988116370219915, "IMATINIB": 7.228522037921586, "NEXAVAR": 1.2415791757695802, "SUTENT": 1.071672476585781, "TASIGNA": 1.0962708220314366, "TOVIAZ": 3.290525796172336, "TOZINAMERAN": 1.2242187713166142, "XOLAIR": 2.278699143611436, "null": 3.4809418720626737}
\ No newline at end of file
+{"NUCALA": 25.800555354328807, "null": 0.7153526512461432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5353.json
index a127599afc5..14b9fca22ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5353.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5353.json
@@ -1 +1 @@
-{"ABRAXANE": 9.370436500008594, "AFINITOR": 7.061031308176213, "ALIMTA": 1.124192615691427, "ANORO": 1.2594937697567443, "ARAVA": 1.4794784001262986, "ATEZOLIZUMAB": 8.224467725938316, "AVASTIN": 1.4366712418232468, "BEDAQUILINE": 1.289322560040355, "BENLYSTA": 1.1519866085919603, "BEVACIZUMAB": 2.341912820587715, "BUSULFAN": 3.9299150183359046, "CAELYX": 2.9870909385078663, "CAPECITABINE": 1.2861908933483348, "CELLCEPT": 2.3377251739106857, "CHAMPIX": 2.5022053444566943, "CICLOSPORIN": 2.444316950741806, "CIMZIA": 2.040270593375836, "COAPROVEL": 1.7997521215741583, "COMBIVIR": 1.1597910513168577, "COSENTYX": 3.685254843293102, "COVID19": 1.151576155517039, "CYTARABINE": 1.220107820891114, "DEXAMETHASONE": 1.598166843539379, "DOCETAXEL": 2.1575535697871917, "DOXORUBICIN": 1.992755737370992, "ENTYVIO": 3.5568019443972068, "ETANERCEPT": 5.967306600523477, "EVEROLIMUS": 5.01274661406502, "EXJADE": 1.1109954334278842, "FASLODEX": 1.3329640086319343, "FILGRASTIM": 4.5161053343012325, "FULVESTRANT": 1.2419653357258054, "HALAVEN": 3.0329397701465703, "HERCEPTIN": 1.0966897820791564, "HUMIRA": 2.1600167926373794, "IBRANCE": 1.892688174717662, "IBUPROFEN": 1.0177695191506586, "IMATINIB": 2.986113713927086, "INCIVO": 1.9792497885773088, "INFLIXIMAB": 4.513483320089829, "INLYTA": 1.8055317482253657, "IRESSA": 2.9457374622225267, "JAKAVI": 1.3279038691137457, "LAMIVUDINE": 2.092034122131244, "LENVIMA": 1.4227831079737203, "LEVOFLOXACIN": 1.5813040169010204, "MABTHERA": 1.748986632820439, "MERCAPTOPURINE": 3.627643433409321, "METHOTREXATE": 5.725417978367167, "MYCOPHENOLATE": 1.5220617833974055, "NEXAVAR": 2.2890906393397765, "PEGASYS": 1.6619896998429762, "PEGINTERFERON": 3.348314523951591, "PEGINTRON": 1.6362857642195507, "PEMBROLIZUMAB": 1.5110323339812022, "PEMETREXED": 2.584181272144885, "PROTELOS": 9.7200562044117, "RAPAMUNE": 7.704345945818331, "RELVAR": 1.8045869450010577, "RINVOQ": 2.082510743071653, "ROACTEMRA": 4.2709706922509145, "STIVARGA": 3.5164763401527064, "SUTENT": 7.905219352681657, "TAGRISSO": 2.0692533413201595, "TAMIFLU": 1.8042129644218083, "TOZINAMERAN": 1.2540555882572018, "TRELEGY": 2.396665829430584, "VIRAMUNE": 5.449754130300336, "XELJANZ": 1.579482699540668, "XELODA": 2.1701152747591235, "null": 1.024152874943918}
\ No newline at end of file
+{"null": 0.7437140097535307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5354.json
index ec8f7102229..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5354.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5354.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.8389941774940357, "ARIPIPRAZOLE": 1.2167225181265262, "AUBAGIO": 3.12683396339216, "AVAMYS": 2.196162140511912, "AZILECT": 3.906124373508813, "BENLYSTA": 1.7650373531175512, "BENZODIAZEPINES": 13.086613918213608, "BONVIVA": 3.7582723028538094, "BRIDION": 2.127181872881548, "BUPIVACAINE": 2.299846032202524, "CARBIDOPA": 3.965406088917108, "CELECOXIB": 1.03841929613136, "COMIRNATY": 1.359250678865762, "COMTAN": 4.792740523184088, "COSENTYX": 1.877674919887744, "CYMBALTA": 1.2882598052176883, "ENTACAPONE": 3.3393979533287625, "EVISTA": 1.0175626408186509, "EXFORGE": 2.1215067836212778, "FENTANYL": 1.4715318522643837, "FIRDAPSE": 1.2122827091873905, "FORSTEO": 1.1245557367757189, "FULVESTRANT": 1.3611786042684777, "GARDASIL": 1.9105856466647737, "GILENYA": 7.327885998189389, "HEPSERA": 2.1368420258205894, "IMATINIB": 2.7920799647795715, "INFANRIX": 3.71586303580453, "KEYTRUDA": 1.03462234576466, "LACOSAMIDE": 1.5464946947252154, "LATUDA": 1.7371394813224137, "LEVODOPA": 7.844531657826774, "LYRICA": 1.0036375799034285, "MIDAZOLAM": 3.2797285819601587, "OPTIMARK": 16.99093514477029, "RISPERIDONE": 2.581078911780785, "SHINGRIX": 1.7581862724523802, "SIFROL": 1.7508250875121594, "STALEVO": 5.751234979080472, "TOZINAMERAN": 2.053993429868784, "TWINRIX": 3.303751596059743, "VAXZEVRIA": 1.1760762619916327, "VIAGRA": 1.0335017471214354, "XELJANZ": 1.9628177238967603, "XOLAIR": 1.020405117271491, "ZYPADHERA": 1.8711534936313945, "null": 1.1201591526555257}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5355.json
index 3b569964453..89bd1f90f9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5355.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5355.json
@@ -1 +1 @@
-{"ICLUSIG": 138.05836805067898}
\ No newline at end of file
+{"ACLIDINIUM": 2.286225686888364, "ACTOS": 2.2800641442735667, "ADCIRCA": 6.78110142447869, "ADEMPAS": 3.2755053627031425, "AFINITOR": 1.3384000810354293, "ALEMTUZUMAB": 1.4655518107674432, "ALIMTA": 4.193107464974718, "AMBRISENTAN": 3.306428790812638, "AMIKACIN": 2.5768331030786094, "AMINOSALICYLIC": 2.647837925592657, "ANORO": 38.17418876090326, "APIXABAN": 6.018607878443826, "ARANESP": 0.3298367077387246, "ARAVA": 0.0449118815399335, "ASPARAGINASE": 0.6915756708780056, "AVAMYS": 2.088024652666327, "AVASTIN": 2.716996919642155, "AZATHIOPRINE": 5.407199636696437, "AZTREONAM": 6.239221114461407, "BEDAQUILINE": 4.7528885389955535, "BEVACIZUMAB": 2.453586118885069, "BOSENTAN": 6.540342458308255, "BRIDION": 1.256999494518075, "BRILIQUE": 9.460213237844595, "BUDESONIDE": 4.193687167688098, "BUSULFAN": 0.6032637707543863, "CABOMETYX": 1.9224776906614005, "CANCIDAS": 2.0902331337684217, "CASPOFUNGIN": 3.125288015284393, "CELLCEPT": 0.3739674583851277, "CHAMPIX": 0.7984379474064058, "CICLOSPORIN": 0.861506906197838, "CIMZIA": 0.1394524801050717, "CLOPIDOGREL": 8.326113218946862, "COLOBREATHE": 26.677273143342997, "COMIRNATY": 0.2014668276545681, "COSENTYX": 0.4738068815366441, "CYTARABINE": 0.3011769334561684, "DELAMANID": 3.0335211794686545, "DEXAMETHASONE": 1.119545759085931, "EFIENT": 6.7696065688410485, "ELIQUIS": 6.25949043279129, "ENOXAPARIN": 9.991761795212016, "ENTRESTO": 0.5501533194297683, "ENVARSUS": 26.029058926580912, "ESBRIET": 3.4221937689463164, "EVEROLIMUS": 2.70950515316095, "EXJADE": 0.897825814535538, "FASENRA": 1.3325140519926513, "FENTANYL": 0.2657082618906661, "FILGRASTIM": 2.3648124959167345, "FLUTICASONE": 16.209915613016683, "GARDASIL": 0.1191087057949835, "IBRANCE": 0.5211064557602777, "IBUPROFEN": 0.457424481675786, "INLYTA": 2.5164452478470167, "INTEGRILIN": 14.394136447758727, "IRESSA": 4.967856209861063, "ISCOVER": 6.329459482389591, "JAKAVI": 0.4635202353012349, "JANUVIA": 0.3210961632516295, "KAFTRIO": 8.35316885671557, "KALYDECO": 18.93344787110714, "KEPPRA": 0.1374457578704369, "KEYTRUDA": 1.6407592856492583, "LAMIRA": 29.319983795503493, "LANTUS": 0.0820068861008366, "LEMTRADA": 2.801905368612896, "LENVIMA": 4.824375820268939, "LEVOFLOXACIN": 1.3614553209612792, "LIXIANA": 4.789159600438884, "MABTHERA": 1.2282054576580792, "MEKINIST": 0.4918427959056344, "MELATONIN": 1.317189327196323, "MEPOLIZUMAB": 0.4470847648419009, "METHOTREXATE": 0.5298509736504341, "MICARDIS": 0.695304393691041, "MIDAZOLAM": 0.6450003373325932, "MULTAQ": 0.8811542279900829, "MYCOPHENOLATE": 0.8436833234021219, "NEULASTA": 0.8156712993742874, "NEXAVAR": 5.931159267589055, "NUCALA": 4.944253392353406, "OFEV": 3.524722204336436, "OLANZAPINE": 0.4543965021473507, "OMALIZUMAB": 0.8039330330228487, "OPDIVO": 0.9144688091994014, "OPSUMIT": 3.1420601104483192, "ORKAMBI": 13.127019942616585, "PAZOPANIB": 2.8429838048179588, "PEGASYS": 1.722378137080847, "PEGINTERFERON": 1.415529179213846, "PEGINTRON": 1.2443217950060628, "PEMBROLIZUMAB": 1.138405085409715, "PEMETREXED": 4.260469760728439, "PLAVIX": 8.709655599285693, "PRADAXA": 5.857052232169145, "RELVAR": 1.5697949707538883, "REVATIO": 2.371609943397331, "RIBAVIRIN": 0.5428189433824707, "RINVOQ": 0.4888604880943141, "RIVAROXABAN": 5.580265929700638, "ROACTEMRA": 0.8758610913325887, "SILDENAFIL": 3.2403597907396637, "SIMPONI": 0.4052540592379173, "SOLIRIS": 0.9617531273404624, "SPIKEVAX": 0.1932597243483443, "SPRYCEL": 0.4277669401848371, "STELARA": 0.170272407461805, "STIVARGA": 0.7037260357800077, "SUTENT": 3.329985580096804, "TAGRISSO": 2.417693027600344, "TAMIFLU": 0.566425188981258, "TICAGRELOR": 11.78474493545197, "TOBI": 72.22021283293803, "TOBRAMYCIN": 2.673796057072801, "TORISEL": 2.4054583742737488, "TOZINAMERAN": 0.3957570084561521, "TRACLEER": 5.124650840363503, "TRELEGY": 2.5630922644881684, "VAXZEVRIA": 0.2744793885397174, "VFEND": 4.06263832952699, "VIAGRA": 0.5523384581885398, "VORICONAZOLE": 3.313785930625285, "VOTRIENT": 3.8723978105776578, "XALKORI": 2.580986328000739, "XARELTO": 11.070736938417404, "XELJANZ": 0.5007213260672058, "XOLAIR": 0.9161124810142331, "XTANDI": 0.3662198840427962, "ZOSTAVAX": 0.2544790316566095, "ZYPREXA": 0.2829799288220208, "null": 1.0305769283291912}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5356.json
index aae74a0243f..dde5cc91e9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5356.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5356.json
@@ -1 +1 @@
-{"null": 1.1754565013842662}
\ No newline at end of file
+{"ABACAVIR": 0.0818457237032433, "ABILIFY": 0.2746450721063875, "ACTRAPID": 0.6969715058551593, "ADCIRCA": 0.9829474153247968, "ADEMPAS": 1.093176724742373, "ADVATE": 48.52981161493238, "AFINITOR": 0.6216861220076646, "AIMOVIG": 0.2603149470203899, "ALEMTUZUMAB": 0.3193260148995074, "ALIMTA": 0.4843330083027166, "AMBRISENTAN": 1.251556151344426, "ANGIOX": 9.510545799059694, "APIDRA": 0.3883228307412023, "APIXABAN": 0.8588359509692144, "ARANESP": 0.7818393542261061, "ARAVA": 0.1235733693393112, "ARIPIPRAZOLE": 0.1167919174319452, "ARIXTRA": 6.716240857934408, "ASPARAGINASE": 0.7674190194079903, "ATRIPLA": 0.0109781718090825, "AUBAGIO": 0.4030675659566637, "AVAMYS": 0.1300865980663458, "AVANDIA": 0.1512574751549879, "AVASTIN": 1.5871937015897886, "AVELUMAB": 1.499334993629302, "AXITINIB": 0.5322966330454995, "AYESURBY": 62.75145750431325, "AZACITIDINE": 0.9063981694163395, "AZATHIOPRINE": 0.2319492937789819, "BENLYSTA": 0.5216981933213953, "BEVACIZUMAB": 1.4791274166785495, "BIKTARVY": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5357.json
index c4eb9bdcc76..e2d09fe9ab6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5357.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5357.json
@@ -1 +1 @@
-{"CICLOSPORIN": 157.71453839144132}
\ No newline at end of file
+{"AZATHIOPRINE": 606.2742771064916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5358.json
index 3c594a12178..e8455c6a7b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5358.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5358.json
@@ -1 +1 @@
-{"null": 1.2243952870523205}
\ No newline at end of file
+{"AZATHIOPRINE": 82.91640941139394, "COMIRNATY": 0.6258676283244051, "SPIKEVAX": 0.5752081136403531, "null": 1.873332202996648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5359.json
index 854e694f8ca..26ea50400b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5359.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5359.json
@@ -1 +1 @@
-{"CELLCEPT": 250.24972189929596}
\ No newline at end of file
+{"ADVATE": 9.704736643486026, "ALEMTUZUMAB": 1.0567743400896876, "ANGIOX": 30.169453963045854, "APIXABAN": 2.135358699659514, "ASPARAGINASE": 2.268977166156065, "AVANDIA": 0.6592500474813007, "BRILIQUE": 19.727763449709418, "BUSULFAN": 2.717758090948571, "CAELYX": 2.6532110974691308, "CICLOSPORIN": 2.133562820558479, "CLOPIDOGREL": 13.276653416602986, "COMIRNATY": 0.0777810622878328, "CRIXIVAN": 2.776626296418392, "CUBICIN": 1.742027073103282, "CYMBALTA": 0.1377576138615179, "CYTARABINE": 1.0247824452311884, "DEXAMETHASONE": 0.6138616250107681, "EFIENT": 17.58699624761932, "ELIQUIS": 32.45981985561951, "ENOXAPARIN": 11.214095751412886, "EPTIFIBATIDE": 73.12327039440846, "EXJADE": 1.4868307345377263, "HEMLIBRA": 6.886895254851355, "HUMAN": 1.734847053012878, "HYDROCORTISONE": 1.076742536541628, "INTEGRILIN": 99.62991781874044, "ISCOVER": 9.673882097408493, "JAKAVI": 0.7170670537627205, "KALETRA": 1.2160666156879554, "LIXIANA": 5.92703356924056, "MEKINIST": 0.9430903983526104, "METHOTREXATE": 0.6425884434099445, "NEXAVAR": 0.3513120882197623, "NOVOSEVEN": 18.8527181572159, "NPLATE": 6.177479515365452, "OPSUMIT": 0.3695918633901507, "PEGASYS": 0.7615152094227697, "PEGINTRON": 0.2573941966037, "PLAVIX": 13.363908847357235, "PRADAXA": 12.297014285110066, "PRASUGREL": 24.23070147526959, "PRAXBIND": 66.54078888492823, "RETEPLASE": 141.09699798553353, "RITUXIMAB": 0.8062661765580987, "SOLIRIS": 0.9496126646341528, "SPIKEVAX": 0.0565448450209693, "SPRYCEL": 1.3498263990128092, "SUTENT": 0.595201726936939, "TASIGNA": 0.7801483037475854, "TEMODAL": 2.6301496434181058, "TICAGRELOR": 12.488215838481278, "TOZINAMERAN": 0.1085245090272952, "VAXZEVRIA": 0.2075967403647525, "VIAGRA": 0.7202997860521404, "VOTRIENT": 0.7022969615229533, "XARELTO": 10.166937592885102, "ZYPREXA": 0.3497576132267959, "null": 1.49499698388316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/536.json
index facd457e0b2..f0c8c488b78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/536.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/536.json
@@ -1 +1 @@
-{"null": 1.910776270828323}
\ No newline at end of file
+{"ABILIFY": 19.96714608383073, "FENTANYL": 104.577100957766, "null": 1.4737725646662443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5360.json
index eb19045da08..c6490dabd28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5360.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5360.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 10.685504653851993, "AMIKACIN": 25.668700284221813, "ASPARAGINASE": 67.07912415846083, "BASILIXIMAB": 37.53034447575481, "BLINCYTO": 123.32032564269905, "BUDESONIDE": 1.9273969627703011, "BUSULFAN": 44.88734426588955, "CASPOFUNGIN": 130.04818223746466, "CELLCEPT": 6.7687935101413, "CICLOSPORIN": 27.321440802620867, "CRESEMBA": 52.345649742807865, "CYTARABINE": 34.97631926772645, "DEXAMETHASONE": 11.967548179451574, "EXJADE": 5.850057172938651, "LEVOFLOXACIN": 3.066830280521802, "METHOTREXATE": 4.1873357195622845, "MICAFUNGIN": 130.36712523267298, "MYCOPHENOLATE": 37.814590684748616, "NOXAFIL": 29.03308476274195, "POSACONAZOLE": 71.80780084153649, "VFEND": 16.050312198702812, "VORICONAZOLE": 77.5129449144517}
\ No newline at end of file
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5361.json
index 1a43e349980..03bf28c8bdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5361.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5361.json
@@ -1 +1 @@
-{"null": 2.7309725355112}
\ No newline at end of file
+{"ADVATE": 9.736029390613254, "AVASTIN": 1.456139322761095, "BRILIQUE": 2.913934923595036, "BRUKINSA": 42.19485753973184, "CLOPIDOGREL": 29.262305548024155, "COMIRNATY": 0.3921909269360674, "EFIENT": 17.394324507521002, "ELIQUIS": 27.83091320945292, "ENOXAPARIN": 44.087884917459846, "JAKAVI": 2.102382873307404, "LIXIANA": 9.625573609595731, "MACITENTAN": 19.77790066788693, "NEXAVAR": 1.0561860521666375, "PEGASYS": 0.3158706111966394, "PLAVIX": 31.569885389472077, "SPIKEVAX": 0.0669032182035324, "STIVARGA": 1.3680755042568875, "SUTENT": 1.2091547495603154, "TAMIFLU": 1.3598692567135402, "TICAGRELOR": 28.148778203318603, "TOZINAMERAN": 0.1930334172669582, "VAXZEVRIA": 0.1943559991468714, "VFEND": 1.184483256549934, "VOTRIENT": 1.734915605355236, "XARELTO": 5.863796995998415, "null": 0.9881059470175724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5362.json
index c90ca5b001e..b28cc5c4981 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5362.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5362.json
@@ -1 +1 @@
-{"null": 1.2706252307038903}
\ No newline at end of file
+{"null": 1.0697945780850726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5363.json
index c474d3f3585..2e8ede1a993 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5363.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5363.json
@@ -1 +1 @@
-{"TWINRIX": 46.456491910898805, "null": 1.2577629178620418}
\ No newline at end of file
+{"BRILIQUE": 10.080651626796415, "CLOPIDOGREL": 15.185905864956712, "COMIRNATY": 0.1624060373754389, "ELIQUIS": 14.86220684319361, "ENOXAPARIN": 9.709479846787358, "INLYTA": 4.709692375194555, "JARDIANCE": 1.6014818214480566, "JEVTANA": 10.794935028984996, "LEVOFLOXACIN": 2.193205997922832, "LIXIANA": 7.682373977381654, "PLAVIX": 12.314906004058235, "SPIKEVAX": 0.358105858159583, "STIVARGA": 3.711476793133804, "SUTENT": 4.062910248861032, "TICAGRELOR": 13.819169447400435, "TOZINAMERAN": 1.5668211654124031, "VAXZEVRIA": 0.5154353032877418, "VIAGRA": 4.050255366374707, "VOTRIENT": 4.222287702930135, "XARELTO": 7.389123279562001, "XTANDI": 7.8092025705464865, "null": 0.6776380318567211}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5364.json
index c66b6e56c65..1a0487ea27f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5364.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5364.json
@@ -1 +1 @@
-{"AVASTIN": 3.602166329713131, "BUSULFAN": 4.335723610741874, "EMEND": 21.41424078711642, "IBUPROFEN": 5.740734703305691, "KEPPRA": 1.104457867211046, "KEYTRUDA": 1.7947642981128331, "MEPOLIZUMAB": 4.484793931896532, "METFORMIN": 28.135875336172823, "NEXAVAR": 2.252510641610624, "STIVARGA": 3.035452100708784, "SUTENT": 2.731271672595573, "TAGRISSO": 6.642481227070001, "null": 1.801452042356397}
\ No newline at end of file
+{"PLAVIX": 159.12407342389068, "XARELTO": 245.64703109920376, "null": 0.1546485840402534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5365.json
index 82991fd18b0..40c91270645 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5365.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5365.json
@@ -1 +1 @@
-{"ARAVA": 1.1393333389541702, "COSENTYX": 1.9395232446659647, "EMPAGLIFLOZIN": 51.46793241103668, "JARDIANCE": 2.0359780547263244, "OLANZAPINE": 3.957270193394228, "SUTENT": 1.945532390393769, "null": 1.8680378058013576}
\ No newline at end of file
+{"null": 1.5491673155342816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5366.json
index 7fcc77c0436..520a7860b49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5366.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5366.json
@@ -1 +1 @@
-{"CANCIDAS": 49.072009640340674, "CICATRIZANTS": 2307.4006469383025, "CICLOSPORIN": 5.18729890679847, "FORTIMEL": 3630.7298320394366, "KONTRASTMITTEL": 3914.518092932005, "null": 3.1369432874498626}
\ No newline at end of file
+{"CLOPIDOGREL": 22.0549002494817, "COMIRNATY": 0.1360948392427799, "ELIQUIS": 27.92987435611951, "PEGINTRON": 6.815147075760715, "PLAVIX": 9.176649971180185, "VAXZEVRIA": 0.3214268761275695, "null": 0.7573797960730213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5367.json
index b1b2a3b70d3..078231be7a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5367.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5367.json
@@ -1 +1 @@
-{"null": 3.012772679945205}
\ No newline at end of file
+{"null": 0.9643385539623236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5368.json
index 9c6da3c5230..952eb485cbb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5368.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5368.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 9.850598780435396, "NPLATE": 32.88185867075616, "PLAVIX": 3.659441874727186, "null": 1.1758759313410312}
\ No newline at end of file
+{"null": 0.7057485925835059}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5369.json
index 5d81e7a82d8..646d4715c4d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5369.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5369.json
@@ -1 +1 @@
-{"null": 2.6146608751144047}
\ No newline at end of file
+{"AIMOVIG": 1.21908379756963, "ARAVA": 4.0794453656895335, "BRILIQUE": 8.42037157187717, "BUDESONIDE": 1.222016999977228, "CICLOSPORIN": 0.7649980725009157, "CLOPIDOGREL": 6.6273605663488615, "COMIRNATY": 0.284774443591027, "COSENTYX": 2.781858681898234, "ELIQUIS": 10.860768037378834, "EMTRICITABINE": 14.743719408191971, "HUMIRA": 1.7251837494388818, "JAKAVI": 2.2434705110878865, "LIXIANA": 6.808872444652647, "MMRVAXPRO": 1.2806835772783034, "NPLATE": 6.169661660172122, "PEGASYS": 1.4917649316922474, "PEGINTRON": 1.156054831804991, "PLAVIX": 11.203601975375484, "ROACTEMRA": 2.237518130131931, "SPIKEVAX": 0.0830487650849719, "SUTENT": 2.254501992976191, "VAXZEVRIA": 0.1665624358326855, "VFEND": 2.1958086240305077, "XARELTO": 8.985751905708424, "null": 1.1314401660976914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/537.json
index 2ebdf9131cc..35032404d77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/537.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/537.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6327902846829228}
\ No newline at end of file
+{"GARDASIL": 145.51225347647076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5370.json
index 1c798acee3f..87fa7ff20ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5370.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5370.json
@@ -1 +1 @@
-{"ABRAXANE": 4.013792314933522, "AFINITOR": 17.805555917671324, "ALEMTUZUMAB": 22.0039540849673, "ALIMTA": 20.667109300032763, "ALPELISIB": 7.85130941763764, "ARIPIPRAZOLE": 4.518729412928821, "ASPARAGINASE": 6.362803053901457, "ATEZOLIZUMAB": 19.538782463051007, "AUTOLOGOUS": 248.2440796808056, "AVASTIN": 5.809776800295488, "AVELUMAB": 11.506867451942869, "AXITINIB": 10.235257851890683, "AZACITIDINE": 2.2990966643045407, "BEVACIZUMAB": 9.19484483244863, "BORTEZOMIB": 10.07119456556988, "BUSILVEX": 48.793652386192434, "BUSULFAN": 47.55871649349039, "CABOMETYX": 11.877159368091853, "CAELYX": 16.872895737343462, "CAPECITABINE": 12.20438660192316, "CARFILZOMIB": 3.4873631141885566, "CARMUSTINE": 34.98697437223768, "CETUXIMAB": 12.816613870387014, "CICLOSPORIN": 3.784468538439572, "CLOFARABINE": 10.625306983762046, "COTELLIC": 8.15032580005422, "CYTARABINE": 15.740472236651442, "DABRAFENIB": 6.212920658691106, "DENOSUMAB": 9.880017584135532, "DEXAMETHASONE": 3.907924431932402, "DOCETAXEL": 11.1819402652812, "DOXORUBICIN": 6.448123299390503, "EMEND": 5.61541955424712, "ERBITUX": 19.15913965359837, "EVEROLIMUS": 11.204110676464571, "FASLODEX": 1.6763296775282623, "FILGRASTIM": 12.74216972681663, "FOTIVDA": 15.17872435955698, "FULVESTRANT": 4.880115684873705, "HALAVEN": 16.62397688200028, "HERCEPTIN": 8.114971067489925, "IBRANCE": 3.0542357538811973, "IMATINIB": 2.3608688022802897, "INLYTA": 3.990599265402368, "IPILIMUMAB": 1.2337836638754225, "IRINOTECAN": 16.573972843345164, "JEVTANA": 4.148808423897667, "KALETRA": 1.3070064182950394, "KEYTRUDA": 2.7287166109150296, "KISQALI": 2.0309088798652577, "LENVIMA": 6.065694936931237, "LONSURF": 1.00364797099502, "MABTHERA": 4.347918998995172, "MEKINIST": 1.3091613818992411, "MELPHALAN": 29.711473393345468, "MERCAPTOPURINE": 5.434794374256518, "METHOTREXATE": 6.074778511578046, "MYCOPHENOLATE": 1.731430403067021, "NEULASTA": 3.682606829417447, "NEXAVAR": 4.406268651420727, "NORVIR": 1.4921206402848182, "NOXAFIL": 2.6580712168914555, "OSIMERTINIB": 9.77079322761784, "PACLITAXEL": 2.8878591677951824, "PAZOPANIB": 2.913754855245118, "PEGFILGRASTIM": 13.12904535157648, "PEMBROLIZUMAB": 5.08786367137818, "PEMETREXED": 7.7321859486767535, "PIQRAY": 7.152458026021125, "RADIATION": 20.097733810354235, "REGORAFENIB": 16.534102229623297, "RITUXIMAB": 2.704544466110942, "SORAFENIB": 8.28979992726653, "STIVARGA": 9.972290900157718, "SUNITINIB": 17.0382805141317, "SUTENT": 10.791726273551149, "TAGRISSO": 3.283513389119108, "TAXOTERE": 10.3136214171609, "TEMODAL": 2.402037579790392, "TEMOZOLOMIDE": 3.8913693932643, "TEMSIROLIMUS": 15.267585899345825, "TEPADINA": 61.453650752156, "THERAPEUTIC": 27.58822158590593, "THIOTEPA": 62.6153191884963, "TOPOTECAN": 10.095124714877947, "TORISEL": 8.135266549182274, "TRODELVY": 16.592205532591443, "VECTIBIX": 9.803165973594096, "VIRAMUNE": 3.400807573853644, "VOTRIENT": 5.686589905217481, "XELODA": 12.440914443245743, "ZELBORAF": 2.962792836266497}
\ No newline at end of file
+{"METHOTREXATE": 146.15393057542502, "null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5371.json
index 664280acb2c..b8e70a8ceee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5371.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5371.json
@@ -1 +1 @@
-{"null": 4.010584589699205}
\ No newline at end of file
+{"CLOPIDOGREL": 2.9652996448511435, "COMIRNATY": 0.0913240629993729, "ELIQUIS": 13.448903308587411, "SUTENT": 1.5377083873451751, "TOZINAMERAN": 1.615823586909635, "VAXZEVRIA": 0.1249722445568446, "null": 2.0458683465531657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5372.json
index 55a5fcb9ff1..d1f034b043e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5372.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5372.json
@@ -1 +1 @@
-{"null": 1.9662913221615863}
\ No newline at end of file
+{"CLOPIDOGREL": 19.689211922790243, "PLAVIX": 17.45521327449445, "null": 0.6247215457498482}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5373.json
index bc34b549a23..3080300aecc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5373.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5373.json
@@ -1 +1 @@
-{"null": 1.2723219839493107}
\ No newline at end of file
+{"ELIQUIS": 42.23872369664178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5374.json
index 0e978170760..b3b978f19fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5374.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5374.json
@@ -1 +1 @@
-{"CICLOSPORIN": 7.719240126966397, "FENTANYL": 5.451851313915949, "null": 1.7156660942295023}
\ No newline at end of file
+{"CLOPIDOGREL": 22.52081310354528, "COMIRNATY": 0.2077360794553045, "ELIQUIS": 23.95401326479443, "VAXZEVRIA": 0.6373836056873315, "null": 0.7437700143715388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5375.json
index 9f6a151beab..0f6aa689f16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5375.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5375.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 4.805222502931265, "BUDESONIDE": 2.446321606411439, "CLOPIDOGREL": 1.892825433234507, "COSENTYX": 2.5304662289178874, "ENTYVIO": 46.74572706225303, "HUMIRA": 5.501050560822975, "LEFLUNOMIDE": 21.005494902487907, "PREVENAR": 16.423148171415633, "REMSIMA": 230.5545196447674, "ROTATEQ": 198.6830155109137, "SIMPONI": 3.0455893958702296, "XELJANZ": 12.605678648686649, "null": 1.0060672592330488}
\ No newline at end of file
+{"null": 0.7883024379779383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5376.json
index df30a2ae6fa..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5376.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5376.json
@@ -1 +1 @@
-{"ANIDULAFUNGIN": 149.71178760117215, "ESOMEPRAZOLE": 26.712879623594432, "HUMALOG": 49.34177021652342, "INSULIN": 10.693664890472649, "PEMBROLIZUMAB": 20.00576718863162}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5377.json
index 5366d1e70ea..8f26154e756 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5377.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5377.json
@@ -1 +1 @@
-{"ENVARSUS": 960.2672617602084, "LANTUS": 4.357369219031158, "NPLATE": 70.97405534452291, "SOLIRIS": 34.63443148832581}
\ No newline at end of file
+{"COMIRNATY": 0.315015337906429, "GARDASIL": 8.90084121236159, "null": 1.086276799205236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5378.json
index 6194913967f..8908d041f86 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5378.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5378.json
@@ -1 +1 @@
-{"ABATACEPT": 1.4494149262598992, "ACTOS": 34.3031300088349, "APIXABAN": 10.967333982460408, "ARAVA": 2.307347809628296, "BELIMUMAB": 91.81517002415158, "BENLYSTA": 4.533598841618911, "BUDESONIDE": 12.952186524893628, "CANAGLIFLOZIN": 82.72575419753434, "FASENRA": 5.335703318262164, "HUMALOG": 1.1206626636562302, "INCRUSE": 15.7555353573988, "INVOKANA": 19.399175792702227, "JANUMET": 3.9167183064023208, "MEPOLIZUMAB": 17.889475495498083, "NUCALA": 10.54796757817624, "OMALIZUMAB": 6.431103832172015, "OPSUMIT": 2.6988065021335736, "XOLAIR": 1.5511578750495305, "null": 1.42985559868221}
\ No newline at end of file
+{"null": 0.7199158905365257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5379.json
index 07178a6ff11..d435c3ece18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5379.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5379.json
@@ -1 +1 @@
-{"SUBOXONE": 62.22198879561816, "null": 2.1384046678205544}
\ No newline at end of file
+{"ADALIMUMAB": 1.5621262729509926, "APIXABAN": 1.335033402666666, "ARIXTRA": 12.967585947209905, "AVANDIA": 1.8130266390310807, "BRILIQUE": 18.002026949195187, "BRINTELLIX": 0.9963504848633752, "BUPRENORPHINE": 1.2112147607388133, "CHAMPIX": 0.4523404164730561, "CIMZIA": 0.3166879324365702, "CLOPIDOGREL": 5.329364590037511, "COMIRNATY": 0.2884061786679399, "CYMBALTA": 0.6849576298466225, "EFIENT": 11.387880975385707, "ELIQUIS": 23.59546772521708, "ENOXAPARIN": 6.033596004113435, "EVENITY": 3.578442986039483, "EVISTA": 4.581475543263785, "EYLEA": 2.517393947639739, "HARVONI": 3.049237843951357, "INTEGRILIN": 13.3021975125005, "KEYTRUDA": 0.4471495964356206, "LIXIANA": 6.301820941326927, "MEKINIST": 1.7370954052220275, "NEXAVAR": 0.787597512722482, "PEGASYS": 0.9102242206707044, "PLAVIX": 29.186411200444876, "PRADAXA": 15.779312018217611, "ROACTEMRA": 1.1629293199869544, "SOLIRIS": 1.1270097843927809, "SPIKEVAX": 0.1739486831512405, "SUTENT": 1.3840493426443, "TOZINAMERAN": 0.3411611930729632, "VAXZEVRIA": 0.3882404081260984, "VOTRIENT": 1.5301820279830731, "XARELTO": 23.98177836364397, "XELJANZ": 0.4320620151093398, "XTANDI": 0.6403009918813324, "ZOSTAVAX": 1.2307758008272525, "ZYPREXA": 0.458862069261824, "null": 0.9745785058875712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/538.json
index 7d4812469c3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/538.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/538.json
@@ -1 +1 @@
-{"ASPARAGINASE": 121.48788414995752, "ONCASPAR": 199.4393686798386, "PEGASPARGASE": 575.9895961791626, "null": 1.4748266597185058}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5380.json
index 9b205db9a9e..0decd029077 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5380.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5380.json
@@ -1 +1 @@
-{"KEPPRA": 3.3469187944263923, "SUBOXONE": 3.3340712938529053, "null": 9.817096270568506}
\ No newline at end of file
+{"BRILIQUE": 19.47076909181008, "CLOPIDOGREL": 21.204885766957872, "COMIRNATY": 0.2341061037320913, "ELIQUIS": 16.52552753622925, "PLAVIX": 21.71155151268448, "PRAXBIND": 384.43779001517566, "VAXZEVRIA": 0.2851230030111158, "XARELTO": 31.698128636877968, "null": 0.8398771039578925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5381.json
index f4ec16902b4..666cd9984a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5381.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5381.json
@@ -1 +1 @@
-{"ALISKIREN": 163.4984966064616, "AMLODIPINE": 1266.7035623438549, "CAFFEINE": 1276.726816297091, "LANTUS": 2.111162610249816, "LEVOFLOXACIN": 165.60940022887206, "RISPERIDONE": 41.009342614502486}
\ No newline at end of file
+{"null": 0.7326587296750037}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5382.json
index f9dbbe5c3f9..b054164dac3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5382.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5382.json
@@ -1 +1 @@
-{"ATRIPLA": 63.59495811946002, "DESCOVY": 1.7334997563519987, "EVENITY": 1.0947226002475956, "GENVOYA": 1.4089336831084067, "HEPSERA": 3.6000743399115893, "KALETRA": 6.505589673364803, "STRIBILD": 39.76729575086082, "TRUVADA": 66.22581992318202, "VIREAD": 15.613076504346932}
\ No newline at end of file
+{"null": 1.2467472781160776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5383.json
index 8f29a7f2e01..2128b1e46cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5383.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5383.json
@@ -1 +1 @@
-{"ATRIPLA": 1.802479746703629, "BUPRENORPHINE": 2.907422192268827, "PLAVIX": 352.4772273286153}
\ No newline at end of file
+{"JANUVIA": 55.17256324537502, "null": 0.9932040047199518}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5384.json
index 40c3490c7da..a025b62cab9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5384.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5384.json
@@ -1 +1 @@
-{"APIDRA": 366.7779925124033}
\ No newline at end of file
+{"AFINITOR": 1.646670656185523, "BRILIQUE": 8.053802164459556, "CELLCEPT": 2.3069405872898807, "CLOPIDOGREL": 6.308151663415908, "COMIRNATY": 0.1127915294560526, "DEXAMETHASONE": 2.0055001369481844, "ELIQUIS": 20.220478731498943, "IBRANCE": 0.9785809660544462, "INCIVO": 17.434684076443634, "LIXIANA": 12.95557426756336, "NEXAVAR": 1.8558935856650896, "PEGASYS": 2.493162542268886, "PEGINTERFERON": 7.772747236671253, "PEGINTRON": 2.5254171607097837, "PLAVIX": 12.931834589154926, "SUTENT": 6.045258780466201, "TICAGRELOR": 10.6583566207891, "VAXZEVRIA": 0.1776024338904291, "VOTRIENT": 3.0485178520053084, "XARELTO": 45.96255273256549, "XELJANZ": 0.9089532918694416, "null": 0.7536116077797586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5385.json
index 7370022252a..76f9cb762f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5385.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5385.json
@@ -1 +1 @@
-{"ADVAGRAF": 7.873443172391126, "ALEMTUZUMAB": 9.396115394781216, "ALIMTA": 1.574230678736814, "ALL": 5.4626420270326665, "AMIKACIN": 7.609418994484369, "ANIDULAFUNGIN": 32.04139621301433, "APROVEL": 2.0720312879652574, "ARANESP": 13.43277067963261, "ASPARAGINASE": 6.308935013096033, "AUTOLOGOUS": 40.39871300762043, "AVASTIN": 1.8634460107766333, "AZACITIDINE": 4.130361469672551, "AZTREONAM": 6.5848186566809535, "BASILIXIMAB": 10.207100041941702, "BOCEPREVIR": 3.90012924023044, "BORTEZOMIB": 5.786790440888698, "BOSENTAN": 4.439462878133713, "BRILIQUE": 1.2569011679613633, "BUDESONIDE": 1.1242186589917909, "BUMETANIDE": 3.3194734821854173, "BUSILVEX": 7.743620550804389, "BUSULFAN": 10.286826091907466, "BYETTA": 1.2439782015027887, "CAELYX": 1.576729842066184, "CANCIDAS": 18.17512832966768, "CARFILZOMIB": 4.016244281530759, "CARMUSTINE": 1.985214812470636, "CASPOFUNGIN": 24.598947909825156, "CELLCEPT": 3.8427621192294414, "CICATRIZANTS": 88.44252085104105, "CICLOSPORIN": 7.57077338595741, "CLADRIBINE": 6.7989066677518455, "CLOFARABINE": 18.03431775606538, "CRESEMBA": 4.9517323139424425, "CRIXIVAN": 2.544399455236729, "CUBICIN": 8.244554343151947, "CYTARABINE": 6.739153860369067, "DAPTOMYCIN": 11.07517215059124, "DARBEPOETIN": 37.97844336770435, "DEFITELIO": 75.27726498668905, "DESLORATADINE": 2.172706433892237, "DEXAMETHASONE": 4.893857759065851, "DEXMEDETOMIDINE": 8.805195481335653, "DIFICLIR": 4.835982362881562, "DOXORUBICIN": 2.420876958207874, "EMTRICITABINE": 2.134475171057049, "EPIVIR": 1.33147316154783, "ESOMEPRAZOLE": 2.3906239330462835, "EVEROLIMUS": 1.839218981175441, "EXJADE": 2.6130449156549465, "EXVIERA": 1.4956797181030197, "FASLODEX": 1.0804022227714656, "FENTANYL": 1.82798363532282, "FILGRASTIM": 5.779657534825653, "FLUTICASONE": 9.016775606380053, "GALVUS": 1.384190760250865, "GANCICLOVIR": 11.93025485977306, "HUMAN": 1.4348702744743989, "HYDROCORTISONE": 4.937040480149458, "IBUPROFEN": 2.3871455800737422, "ICLUSIG": 2.38448957811382, "INCIVO": 3.2953642402732037, "INTEGRILIN": 3.976621746033693, "INTELENCE": 3.835737953232934, "IPILIMUMAB": 1.03351463665802, "IRESSA": 1.0429952400927809, "JAKAVI": 2.6163643856469765, "JEVTANA": 4.186135230579333, "KEPPRA": 1.3562297812021469, "KEYTRUDA": 1.38558702663347, "KYMRIAH": 5.148071230720524, "KYPROLIS": 1.452541989591628, "LACOSAMIDE": 2.147959179417983, "LAMIVUDINE": 1.1046224461828442, "LEVETIRACETAM": 2.963596066497437, "LEVOFLOXACIN": 3.0914899425731117, "MABTHERA": 2.6259913780759443, "MELATONIN": 1.6656813481261266, "MELPHALAN": 7.120862460936055, "METHOTREXATE": 1.716120665902218, "MICAFUNGIN": 9.906876627679932, "MIDAZOLAM": 2.650422557865285, "MULTAQ": 1.785380298859692, "MYCAMINE": 10.737063867899556, "MYCOPHENOLATE": 4.072562385233291, "NEXAVAR": 1.2248566736118716, "NOVOSEVEN": 39.48044985677456, "NOXAFIL": 2.4287226916008247, "NPLATE": 1.763015893076058, "OLYSIO": 2.102722631470594, "ONCASPAR": 2.4180213598553766, "OPDIVO": 1.0352766194827627, "OPSUMIT": 2.115070514807774, "PANTOPRAZOLE": 1.5299167589257567, "PEGASYS": 1.3005145865086911, "PEGINTERFERON": 1.2611730454055097, "PEGINTRON": 1.0079927070524928, "PEMBROLIZUMAB": 1.2756400808927109, "PEMETREXED": 1.2317201125894954, "PLAVIX": 1.2599891028746022, "POSACONAZOLE": 4.38267615005681, "PRADAXA": 2.8223763014192222, "PRAXBIND": 20.3051244338344, "RAPAMUNE": 1.3848165340536012, "RASILEZ": 1.1271517461958918, "REBETOL": 2.1585928739019797, "REMDESIVIR": 6.540283728499924, "REMICADE": 1.0139111280231805, "REVATIO": 2.164120203446809, "REVLIMID": 1.38285576491973, "RIBAVIRIN": 1.039473684577101, "RITUXIMAB": 1.2859949202312493, "ROACTEMRA": 3.063738967462874, "RUXOLITINIB": 1.816948299538206, "SAMSCA": 6.9206296233715205, "SODIUM": 10.636908014887943, "SOLIRIS": 5.58569698589678, "SOVALDI": 2.8095887428918456, "SPIRONOLACTONE": 2.989912938021328, "SUTENT": 2.706371180706926, "SYNAGIS": 1.6297013213242737, "TACROLIMUS": 2.2936034813393302, "TAMIFLU": 3.639019186038419, "TEMODAL": 2.083632835555644, "TENOFOVIR": 2.5388572546855173, "THIOTEPA": 4.057598456527057, "TICAGRELOR": 1.299177530476449, "TOBRAMYCIN": 3.664853757759001, "TOCILIZUMAB": 1.953289132815306, "TRACLEER": 3.7653623141773607, "VEKLURY": 7.202359625838215, "VENCLYXTO": 4.877874921754071, "VENETOCLAX": 2.474981630352914, "VFEND": 2.560230636961792, "VORICONAZOLE": 4.690752964401965, "XALKORI": 1.4613011568977283, "XELODA": 1.7015464730866168, "YERVOY": 1.166185455095715, "YESCARTA": 3.287513838781345, "YONDELIS": 8.030080488581554, "null": 1.2115446232846014}
\ No newline at end of file
+{"AFINITOR": 0.5954802911233156, "AIMOVIG": 0.6555674700941055, "ARANESP": 0.4607478386676365, "ARAVA": 0.1363627382407733, "AVASTIN": 0.7789966415903012, "AVONEX": 8.12197157256277, "BIKTARVY": 0.934098408172853, "BRAFTOVI": 1.1281360019816011, "BRILIQUE": 2.137010282112985, "BYDUREON": 0.565009275503228, "BYETTA": 1.4172139175846998, "CELLCEPT": 0.8549000325597572, "CHAMPIX": 0.2218287681478936, "CIMZIA": 0.7519891882036273, "CLOPIDOGREL": 0.4947843818885498, "COMBIVIR": 1.5490095373978567, "COMIRNATY": 0.1847022780441512, "COSENTYX": 0.7765671770689605, "CYMBALTA": 0.5633407168721989, "DEXAMETHASONE": 0.8398612909785705, "DOCETAXEL": 0.7140283913805109, "ELIQUIS": 2.842911626813601, "ENTRESTO": 0.3822270331266679, "ENTYVIO": 3.0361757505943547, "EPADERM": 104.38002836808998, "ESBRIET": 0.8426374755547155, "EXJADE": 0.8004136687210401, "FASLODEX": 1.0106653911769354, "FENTANYL": 1.202162388454989, "FIRDAPSE": 2.041104762101816, "FORSTEO": 4.518052595958407, "GARDASIL": 0.3706920203127841, "HUMIRA": 1.9228881798887068, "HYDROCORTISONE": 1.4990615462409485, "IBRANCE": 0.8434010783492581, "IBUPROFEN": 0.4637315382027377, "ICLUSIG": 1.2694460083969372, "INCIVO": 20.332976185088366, "INLYTA": 1.2063272923882933, "ISENTRESS": 3.1961623961660885, "JANUMET": 3.048182863131012, "JANUVIA": 2.105559600716193, "JARDIANCE": 0.5073488035698435, "KEPPRA": 0.625388273070117, "KEYTRUDA": 0.3295273695206849, "LIXIANA": 1.7342555483183104, "LYRICA": 0.6982540961575092, "METHOTREXATE": 0.8791646879810896, "NEXAVAR": 0.3172197601554783, "OFEV": 1.0105478027203003, "OLANZAPINE": 0.3698180102352211, "OPSUMIT": 0.4228053250170399, "OPTIMARK": 1.030815123248067, "PEGASYS": 4.931697417775261, "PEGINTERFERON": 9.805466173611904, "PEGINTRON": 1.872622170084986, "PLAVIX": 1.477395204146625, "RIBAVIRIN": 1.7898138491652325, "SAXENDA": 1.329415699695197, "SIMPONI": 0.8300260338487045, "SOLIRIS": 0.6121089041041898, "SPIKEVAX": 0.1770060042549511, "SPRYCEL": 1.2187719837910485, "STELARA": 0.7886346916932223, "STEROIDS": 13.823249904224234, "SUTENT": 3.584597450537875, "TASIGNA": 0.704440488422959, "TOZINAMERAN": 0.1830378454484517, "VAXZEVRIA": 0.2101499611399476, "VOTRIENT": 1.108983907630945, "XELJANZ": 2.015030974891797, "XOLAIR": 0.4535559339913978, "XYREM": 1.935280626002884, "ZOSTAVAX": 2.2174884724221564, "ZYPREXA": 0.7418436007641424, "null": 2.6478225664482773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5386.json
index 17865d13e7d..435b11f700c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5386.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5386.json
@@ -1 +1 @@
-{"null": 2.067710689608565}
\ No newline at end of file
+{"COMIRNATY": 1.9607438333029217, "PEGASYS": 3.2380903027789647, "SPIKEVAX": 1.2710033771049687, "VAXZEVRIA": 3.332866656597804, "null": 0.2970724326508784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5387.json
index 920960a54a7..600d2f805da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5387.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5387.json
@@ -1 +1 @@
-{"AIMOVIG": 1.875436397801229, "ALEMTUZUMAB": 3.0084014570127406, "AUBAGIO": 143.1144337118876, "AVONEX": 55.70613096320757, "BETAFERON": 69.19632833547284, "CHAMPIX": 1.0950916010004663, "CLADRIBINE": 8.726772442789567, "FAMPRIDINE": 34.75634760554862, "FAMPYRA": 55.70703471685937, "GARDASIL": 7.000328285493678, "GILENYA": 15.36785179420972, "HUMALOG": 1.202167478033288, "HUMIRA": 2.41132944218718, "KESIMPTA": 50.33137836897392, "LEMTRADA": 17.257764784611222, "LYRICA": 2.5907315242993483, "MAVENCLAD": 77.61281487196355, "MAYZENT": 92.35270030804791, "OCRELIZUMAB": 23.996016100282844, "OCREVUS": 38.058270279091005, "PLEGRIDY": 42.094731173501, "PREGABALIN": 2.3627923084863034, "REBIF": 25.67628620896644, "REMICADE": 2.0808923698063366, "RITUXIMAB": 1.382255676998915, "SIMPONI": 4.120764921466942, "STELARA": 2.551347505634536, "TASIGNA": 1.0012140999536352, "TECFIDERA": 46.771396749336944, "TERIFLUNOMIDE": 35.87273619557571, "TOVIAZ": 6.419184797446486, "TREMFYA": 2.0713916861042163, "TWINRIX": 15.36636396973925, "TYSABRI": 24.853966529166293, "VIAGRA": 4.001563035040417, "XOLAIR": 1.542536203712496, "ZINBRYTA": 20.702358230624483}
\ No newline at end of file
+{"EXJADE": 93.84489672779354, "JAKAVI": 88.30832907156403, "null": 0.5632691106230296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5388.json
index 120ee30547b..d97391ed455 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5388.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5388.json
@@ -1 +1 @@
-{"AUBAGIO": 37.02130013216005, "SPIKEVAX": 1.4406538605853905}
\ No newline at end of file
+{"ELIQUIS": 31.14468455210082, "null": 0.585019761126208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5389.json
index 298ae7be49e..4e19eaace56 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5389.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5389.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 14.41758214973277, "AUBAGIO": 442.6417017384261, "AVONEX": 52.38570504027653, "BETAFERON": 83.12951191182691, "BUPIVACAINE": 3.164214167574689, "CLADRIBINE": 15.519533093867665, "FAMPRIDINE": 18.416880905597733, "FAMPYRA": 65.08492093100487, "FINGOLIMOD": 43.94406459061196, "GILENYA": 50.62157833187744, "KESIMPTA": 86.02330080684595, "LEMTRADA": 56.60979159502951, "MAVENCLAD": 175.07429808851833, "OCRELIZUMAB": 5.086907429152187, "OCREVUS": 29.09856964033237, "PLEGRIDY": 67.31078049233504, "REBIF": 23.640733938495227, "TECFIDERA": 48.757346912509696, "TERIFLUNOMIDE": 74.31171249524328, "TYSABRI": 66.59342900293417, "ZINBRYTA": 147.53093478950782}
\ No newline at end of file
+{"BRILIQUE": 5.185069041603913, "BUDESONIDE": 7.925522750841215, "CLOPIDOGREL": 14.6089634559228, "ELIQUIS": 11.73867080803951, "ENOXAPARIN": 8.051514057642576, "NEXAVAR": 4.453077289386711, "NOVOSEVEN": 27.37382281177756, "PLAVIX": 8.131550718196586, "PRADAXA": 29.608454478081047, "SPRYCEL": 9.277347037846702, "SUTENT": 0.9645984496737632, "TICAGRELOR": 11.45930800695112, "XARELTO": 20.66909927323392, "null": 1.4504630564695808}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/539.json
index f3d9cd0fff4..1f55fbf03e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/539.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/539.json
@@ -1 +1 @@
-{"KALETRA": 303.6379803569546}
\ No newline at end of file
+{"COMIRNATY": 0.1432706976278878, "HUMALOG": 10.00894076766185, "HUMIRA": 8.72426333525107, "INVOKANA": 212.1455539523325, "JARDIANCE": 18.3028811611038, "LANTUS": 9.557989664770307, "OPTIMARK": 16.186119085325508, "null": 0.8704470929942913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5390.json
index 13f33ff7a5f..40af9869ad4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5390.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5390.json
@@ -1 +1 @@
-{"ENBREL": 31.004383141107738}
\ No newline at end of file
+{"CABOMETYX": 23.051049143210896, "COMIRNATY": 0.0424736488705349, "DOCETAXEL": 10.749513942419506, "HERCEPTIN": 5.160034083773915, "IBRANCE": 0.6088434827305389, "KEYTRUDA": 0.7420133878613784, "OPDIVO": 2.031473398392185, "PAZOPANIB": 69.88264006999313, "PEGASYS": 0.4698016754117792, "SPIKEVAX": 0.059692944329786, "SUNITINIB": 30.246649169899676, "SUTENT": 40.61344201843543, "VAXZEVRIA": 0.0536426767601833, "VOTRIENT": 94.5611094490942, "XOLAIR": 0.9121738333741084, "null": 1.134587245262506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5391.json
index b5ec5aa5b03..8b7c5498fa7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5391.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5391.json
@@ -1 +1 @@
-{"APIDRA": 118.0375707069236, "EYLEA": 391.0920808504305, "IKERVIS": 267.97990693400607, "LANTUS": 35.313953739851186, "NOVORAPID": 16.014334764099562, "TOUJEO": 36.7594532910498}
\ No newline at end of file
+{"COMIRNATY": 0.2721713972532688, "IBRANCE": 6.900609871191678, "SUTENT": 2.4480651699949654, "null": 1.975357306608592}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5392.json
index df3975a47f9..1ecc751a3db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5392.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5392.json
@@ -1 +1 @@
-{"ABACAVIR": 9.396463745113849, "ADALIMUMAB": 1.1404435594030635, "AMIKACIN": 9.484347282901172, "AMINOSALICYLIC": 3.427056268840273, "ANAKINRA": 11.218753785241592, "AVAPRITINIB": 221.49405833462865, "AZATHIOPRINE": 2.3092151046247458, "BEVACIZUMAB": 2.822592450768702, "BRIVARACETAM": 383.9333592629885, "BRIVIACT": 61.94275572432765, "CAELYX": 7.648590483363011, "CANNABIDIOL": 261.95180239719457, "CASPOFUNGIN": 6.244033658629087, "CIDOFOVIR": 60.847392246304615, "COMBIVIR": 8.138254552665765, "DAPTOMYCIN": 15.890956090397513, "DEXAMETHASONE": 4.617778664636292, "ELTROMBOPAG": 75.24112928101874, "ENTECAVIR": 19.48396269195553, "FENTANYL": 2.277454642999196, "FYCOMPA": 81.50660345662867, "HUMAN": 11.08506671796665, "HYDROCORTISONE": 6.838664909761753, "KEPPRA": 32.05695506524039, "LACOSAMIDE": 290.1051023038506, "LAMIVUDINE": 6.862826082977011, "LEVETIRACETAM": 108.75641881042888, "MIDAZOLAM": 10.670049301128088, "PERAMPANEL": 151.4527106111148, "STRIBILD": 1.2900423396291385, "VIMPAT": 6.261785591153815, "VORICONAZOLE": 4.717739569623929, "ZONISAMIDE": 47.622253705920464}
\ No newline at end of file
+{"ANAKINRA": 237.1010437372663}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5393.json
index 61a55fa4fee..b9df47dee55 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5393.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5393.json
@@ -1 +1 @@
-{"COMIRNATY": 2.2910237437353307, "ENBREL": 21.133042977406035, "SPIKEVAX": 2.158726640069617, "TOZINAMERAN": 3.785060574616325, "VAXZEVRIA": 1.3855681713414192}
\ No newline at end of file
+{"AUBAGIO": 2.035777023074312, "CICLOSPORIN": 1.3273737412081472, "COMIRNATY": 0.2204626399657777, "FASLODEX": 2.4903221734512666, "FORSTEO": 2.7084564208969177, "GARDASIL": 1.0097729474717771, "IBRANCE": 2.8965790767574564, "SPIKEVAX": 0.1468245687680923, "SUTENT": 0.9783733814079562, "TESTOSTERONE": 28.38329845833128, "XELJANZ": 2.56580013425024, "null": 2.9157626083163284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5394.json
index 0b99ab0779a..109ef79acb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5394.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5394.json
@@ -1 +1 @@
-{"COMIRNATY": 2.5915127334107493, "SPIKEVAX": 2.571117724806057}
\ No newline at end of file
+{"null": 0.8215158129056229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5395.json
index ebaa98e1949..0b9703849c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5395.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5395.json
@@ -1 +1 @@
-{"COMIRNATY": 4.895190768110581, "TOZINAMERAN": 6.556008980763848}
\ No newline at end of file
+{"COMIRNATY": 0.4692411674087145, "null": 1.4702359818995074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5396.json
index 346d357b0e7..cfe7cd019db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5396.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5396.json
@@ -1 +1 @@
-{"MIDAZOLAM": 18.372625791282527, "MMRVAXPRO": 21.46837729829788, "null": 10.488353438609238}
\ No newline at end of file
+{"AUBAGIO": 7.68491429316602, "COMIRNATY": 0.1491663354850353, "DOCETAXEL": 19.596889298428984, "GARDASIL": 1.656553702329182, "HERCEPTIN": 9.952475578000737, "IBRANCE": 6.170929614891883, "NEXAVAR": 1.8493915291871448, "PEGASYS": 1.6204524808962786, "PEGINTRON": 2.5563502465571144, "SUTENT": 2.6621926292561016, "VAXZEVRIA": 0.0875135566179434, "null": 2.468316126505262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5397.json
index 25ab1055b5e..db2fce85cc7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5397.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5397.json
@@ -1 +1 @@
-{"MMRVAXPRO": 100.51277911411076, "null": 2.6282276649410377}
\ No newline at end of file
+{"null": 10.625427305602074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5398.json
index 565444e1db9..c917ea03c8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5398.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5398.json
@@ -1 +1 @@
-{"null": 1.2574723005795418}
\ No newline at end of file
+{"CLADRIBINE": 1192.8535201374905, "null": 0.6274802474019688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5399.json
index 0a4db084518..3bb23ad3b55 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5399.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5399.json
@@ -1 +1 @@
-{"CANAKINUMAB": 1507.303276494352, "PEGASYS": 4.729710007216791, "PEGINTRON": 8.03650631955333}
\ No newline at end of file
+{"CLADRIBINE": 4026.426509953304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/54.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/54.json
index b8dbdbb1ca5..e2dc3218b30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/54.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/54.json
@@ -1 +1 @@
-{"ACTRAPID": 8.31855174511245, "AFINITOR": 1.5958848467128268, "ALEMTUZUMAB": 1.8896245397489564, "AMIKACIN": 7.868278144604589, "ANAKINRA": 3.4088407597988524, "AVASTIN": 2.725261632807709, "BENLYSTA": 1.995833216614816, "BETAFERON": 10.47828900988403, "BEVACIZUMAB": 2.243181028513752, "BYETTA": 1.2961583599070174, "CELLCEPT": 1.8913007856507131, "CICLOSPORIN": 2.648336107217271, "CIMZIA": 5.650877740085182, "COSENTYX": 2.52569870338455, "DEXAMETHASONE": 1.5480779165175766, "DOCETAXEL": 1.3937069805972824, "ENBREL": 2.148186430149844, "ENTYVIO": 9.92959164608, "EXJADE": 1.793180811864839, "FASLODEX": 1.8303230747501429, "GARDASIL": 1.5578764427141298, "HIZENTRA": 2.528086955448713, "HUMALOG": 1.4713179834027676, "HUMIRA": 6.908129252415575, "INCIVO": 2.1076322238246754, "JARDIANCE": 2.6944837279420786, "LANTUS": 1.4538899149567048, "LEVETIRACETAM": 1.6475988248857276, "METHOTREXATE": 2.122205229408155, "MYCOPHENOLATE": 3.259838442479331, "PEGASYS": 2.8200358057637023, "PEGINTRON": 3.824662725041792, "PROPRANOLOL": 5.575513494058053, "REMICADE": 7.668284365493086, "RINVOQ": 2.276288007385868, "ROACTEMRA": 12.76697828917951, "SIMPONI": 6.352695421455475, "SOLIRIS": 1.43318365920293, "STELARA": 5.931996595032327, "SUTENT": 1.2325969459926105, "TREMFYA": 2.2448150483924554, "XELJANZ": 1.0776273499194382, "ZOMETA": 13.327878876799396, "ZOSTAVAX": 1.3151042668302908}
\ No newline at end of file
+{"ABACAVIR": 1.6609913631815771, "ABILIFY": 0.8550967074230981, "AIMOVIG": 1.8726741492127807, "ATRIPLA": 1.2017139462765607, "AZILECT": 7.453715920437804, "BIKTARVY": 16.211473568022807, "BRINTELLIX": 12.155831564315122, "CELLCEPT": 0.6030359699819595, "CHAMPIX": 57.498055495201605, "CIRCADIN": 11.465604490786784, "COMBIVIR": 2.402627690194404, "COMIRNATY": 0.1916331957866918, "CYMBALTA": 1.700927591996912, "DESCOVY": 5.25433925655206, "EFAVIRENZ": 2.6132998755463577, "ELIQUIS": 0.2144667394880228, "ENTRESTO": 0.3825552205515913, "GARDASIL": 0.210964248818765, "GENVOYA": 6.497984733688627, "IBRANCE": 0.2310101154797641, "JANUMET": 0.4993899235474855, "KEPPRA": 0.7744454816105686, "LATUDA": 1.6447094600110634, "LYRICA": 0.8632255276402304, "MELATONIN": 7.340968484047119, "OCRELIZUMAB": 0.9988862977696316, "OLANZAPINE": 0.4604539801353228, "PEGASYS": 0.2982284260274151, "PEGINTRON": 0.4802588101690811, "SAXENDA": 0.8263888361379367, "SEMAGLUTIDE": 13.85767641076035, "SHINGRIX": 0.385548914027506, "SIFROL": 4.549356890943895, "SPIKEVAX": 0.2550023268833699, "STALEVO": 2.702998184368318, "STRIBILD": 0.8437829635227182, "SUBOXONE": 1.1770429257780683, "SUTENT": 0.1080907200161397, "TAMIFLU": 1.2794925741182936, "TIVICAY": 7.369999789464062, "TOZINAMERAN": 0.7329553627700564, "TRIUMEQ": 5.403626924150437, "TRUVADA": 0.1179362611262071, "VARENICLINE": 24.92171622127777, "VAXZEVRIA": 0.5731886616280436, "VFEND": 3.37318621636723, "VIAGRA": 0.5818139855733926, "XTANDI": 1.5013924848012814, "XYREM": 8.91516435096831, "ZYPREXA": 0.9970050129284734, "null": 2.078897452844542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/540.json
index 62e3876a833..ff225af61de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/540.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/540.json
@@ -1 +1 @@
-{"ACTRAPID": 4.604732110523533, "AIMOVIG": 14.203559456009351, "AMIKACIN": 4.178088750542549, "APROVEL": 6.311806334429481, "BASILIXIMAB": 8.82062798509484, "CELLCEPT": 2.6743739069601165, "CICLOSPORIN": 3.3926519660750487, "CLOPIDOGREL": 1.082266559448324, "COAPROVEL": 3.291196575171782, "CUBICIN": 5.222896514313198, "DACLATASVIR": 10.4227031742893, "DEXAMETHASONE": 1.0816443759494918, "ENTRESTO": 4.921701033935137, "ERENUMAB": 86.87076200210286, "EUCREAS": 7.084855627102629, "EXFORGE": 2.5336996573190254, "EXJADE": 2.342633833001168, "FENTANYL": 2.5494728896214656, "FORXIGA": 1.9994189208537652, "GALVUS": 3.4153728605027305, "GLIBENCLAMIDE": 12.081899525524816, "IBUPROFEN": 7.300396179883529, "INCIVO": 1.6083041561395903, "IRBESARTAN": 6.395079655963421, "JANUMET": 2.3122994608737164, "JANUVIA": 1.4892245928199217, "JARDIANCE": 1.01186352543594, "KALETRA": 1.6656720932000522, "LEVETIRACETAM": 1.71837834764099, "METFORMIN": 10.079941522585113, "MICARDIS": 4.070834331402571, "MIDAZOLAM": 2.128129514204692, "OLYSIO": 3.2301788820576784, "OPDIVO": 1.2402306777908916, "PRIVIGEN": 1.555011365529627, "RASILEZ": 3.9037176749672513, "SOLIRIS": 5.166221789558011, "TRACLEER": 2.339000068891427, "VFEND": 2.5166156093434524, "XELEVIA": 95.8692694470784, "ZONISAMIDE": 18.93129004190845, "null": 2.6178249325926988}
\ No newline at end of file
+{"null": 0.3643902650883761}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5400.json
index a3098ee30f9..c8b4cb61dba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5400.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5400.json
@@ -1 +1 @@
-{"ABACAVIR": 1.7750510496386822, "BENLYSTA": 1.9050510602455293, "BIKTARVY": 3.983226531210247, "BUDESONIDE": 1.1929919770652209, "BYDUREON": 1.5802952072936989, "CELLCEPT": 1.2908094116924953, "COSENTYX": 2.0121848816990338, "CRIXIVAN": 5.7329972241464535, "CYMBALTA": 4.958690877021871, "DEXAMETHASONE": 1.5044421289058514, "DULOXETINE": 2.764969075324298, "ESOMEPRAZOLE": 4.087823959316461, "FAMPYRA": 2.6597416190518715, "FORSTEO": 1.4845624434475846, "FORXIGA": 2.9616085589871965, "GARDASIL": 1.0460118393032702, "INLYTA": 1.335978914773854, "JARDIANCE": 2.2793850735649914, "KALETRA": 1.822239180909213, "LEVOFLOXACIN": 1.135271025978995, "LYRICA": 1.1589196328806208, "OPTIMARK": 2.7015857282212723, "PANTOPRAZOLE": 2.11025283295399, "PEGASYS": 1.6106667703992898, "PEGINTRON": 2.279827764167504, "XTANDI": 1.9979912316713373, "ZOSTAVAX": 1.5776716965340212, "null": 1.441323596212899}
\ No newline at end of file
+{"ABACAVIR": 0.1177878630688773, "ABILIFY": 1.968865145230768, "ACTOS": 0.8520069037644874, "ADVAGRAF": 2.717676761659514, "AERIUS": 2.5932401316823195, "AFINITOR": 0.1527159572453135, "AIMOVIG": 0.1145190290638918, "AMIKACIN": 0.7784413854654463, "APIDRA": 0.3881148435153026, "APIXABAN": 3.9996870601302654, "ARAVA": 0.3888692603221693, "ARIPIPRAZOLE": 1.2154587381306583, "ATRIPLA": 0.200122279722302, "AUBAGIO": 0.2521121501104457, "AVAMYS": 0.1769246509459269, "AXITINIB": 0.6394040934250496, "AXURA": 8.504855877447458, "AZILECT": 14.574263652342466, "BENZODIAZEPINE": 1.6606382481186632, "BETMIGA": 0.5785219689804398, "BEXTRA": 2.919419191066829, "BIKTARVY": 1.5037205459401386, "BORTEZOMIB": 0.917503156890651, "BRILIQUE": 0.1895243296166052, "BRINTELLIX": 1.2243018513932715, "BRIVARACETAM": 4.337772292008388, "BRIVIACT": 2.119041677049975, "BUDESONIDE": 0.2472677440298456, "BUPIVACAINE": 0.609656319650504, "BUPRENORPHINE": 2.481903376178692, "BYDUREON": 0.4108566208079802, "BYETTA": 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3.261384376255992, "KEYTRUDA": 0.1229469674431857, "KYMRIAH": 0.6777022737935287, "LACOSAMIDE": 0.500489843775518, "LANTUS": 0.3261511095017684, "LATUDA": 4.676230114320489, "LEVETIRACETAM": 1.5900174562942062, "LEVODOPA": 10.923715051688882, "LEVOFLOXACIN": 1.7329302769783244, "LYRICA": 3.01621985219676, "MEKINIST": 0.4557745175407841, "MELATONIN": 3.950094370718908, "MEMANTINE": 3.1470164016387168, "METHOTREXATE": 0.1271558262235638, "MICARDIS": 0.2051190498762488, "MIDAZOLAM": 3.127064192882801, "MMRVAXPRO": 0.0988745358093658, "MODERNA": 0.0859143302321361, "MULTAQ": 0.6000455416007816, "NEUPRO": 10.668591887877795, "NIMENRIX": 0.4687295159425254, "NOT": 0.75510587783213, "NOXAFIL": 1.3730936616865106, "OCRELIZUMAB": 1.051141672854595, "OFEV": 0.2159685586445213, "OLANZAPINE": 2.0075955770424336, "ONGENTYS": 24.397770380650236, "OPSUMIT": 0.1010890391014939, "OSELTAMIVIR": 4.045122864211468, "OXYBUTYNIN": 5.711367998435299, "PALIPERIDONE": 4.432568208933654, "PANTOPRAZOLE": 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0.7968896973673119, "TORISEL": 0.7252933320018008, "TOVIAZ": 1.6285580683594771, "TOZINAMERAN": 0.4936262053470039, "TRACLEER": 0.2827590750239998, "TRELEGY": 0.3796366724371847, "TRULICITY": 0.2690678380486376, "TRUVADA": 0.0219769061950598, "VAXZEVRIA": 0.451639494056948, "VFEND": 39.9247386582293, "VIAGRA": 0.1722504298934929, "VIMPAT": 2.0653796496900183, "VORICONAZOLE": 22.376448887865354, "VOTRIENT": 0.1379985469099824, "XALKORI": 0.3222246102055853, "XOLAIR": 0.1267045566137482, "XTANDI": 1.53363934379061, "XYREM": 3.638520376701773, "ZOSTAVAX": 0.1439879098082823, "ZYPADHERA": 1.9351871306900024, "ZYPREXA": 2.159350643355357, "null": 2.4169918749777253}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5401.json
index 5a6e56b624e..9a2da977642 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5401.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5401.json
@@ -1 +1 @@
-{"AFINITOR": 1.7994194597891906, "AMINOSALICYLIC": 2.82479437504366, "BRINTELLIX": 1.9742295494602955, "CEFUROXIME": 59.08739854093133, "COMIRNATY": 1.7216566252226573, "EVEROLIMUS": 7.934051166488537, "GARDASIL": 2.450452707286093, "LEVOFLOXACIN": 1.7124515713253126, "LYRICA": 2.3446628700076526, "OLANZAPINE": 2.18623094350606, "OPTIMARK": 2.1274734560659434, "TAMIFLU": 1.509956106863226, "TOZINAMERAN": 1.3012285312745973, "ZYPREXA": 1.2503698277264232, "null": 1.635673979667879}
\ No newline at end of file
+{"ABILIFY": 15.503110004087238, "AERIUS": 5.594442263832297, "ANTIBIOTICS": 7.925452504116055, "ARIPIPRAZOLE": 26.457331338797804, "ATRIPLA": 0.2588004044318128, "BIKTARVY": 1.0954206674250555, "BRINTELLIX": 2.5964264790287035, "BRIVIACT": 6.941085502194045, "BUPRENORPHINE": 2.490783556451839, "CANAGLIFLOZIN": 31.393055824025748, "CARBIDOPA": 12.747511218165664, "CARIPRAZINE": 31.807090427007594, "CHAMPIX": 6.408686197751896, "CLOPIDOGREL": 0.2736407566363118, "COMIRNATY": 0.0647725050966548, "CYMBALTA": 2.537536189929358, "DULOXETINE": 3.1179175768060383, "ENTRESTO": 0.6657861041875074, "FENTANYL": 0.4870474723430863, "FYCOMPA": 5.23944941306573, "GARDASIL": 0.8735301055352436, "INVEGA": 17.692620719746742, "ISENTRESS": 3.169948029630719, "JARDIANCE": 0.6336676590421048, "KALETRA": 0.9457095547413712, "KEPPRA": 3.9474269924309753, "LATUDA": 30.601852506935607, "LEVETIRACETAM": 2.837230167116293, "LEVODOPA": 11.089738228310518, "LEVOFLOXACIN": 0.7625000558072837, "LURASIDONE": 35.75094149436588, "LYRICA": 1.1978326909318409, "OLANZAPINE": 12.94387113976042, "PEGASYS": 1.9904111992467577, "PEGINTRON": 1.8428152786250465, "PLAVIX": 0.2709215881318347, "PROPRANOLOL": 3.7839357506232414, "RISPERIDONE": 14.608692375920151, "SIFROL": 6.003134274361014, "SPIKEVAX": 0.0972388539101213, "STALEVO": 3.80876539209585, "SUBOXONE": 4.223094164518433, "TAMIFLU": 11.95068004286625, "TOZINAMERAN": 0.2470001027125132, "VAXZEVRIA": 0.1006737934489698, "VFEND": 21.164207312631717, "VIMPAT": 3.284362503392343, "VORICONAZOLE": 12.79315998657443, "ZYPADHERA": 3.010679029354051, "ZYPREXA": 6.832288572019277, "null": 1.9742862225069675}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5402.json
index c69d6bd63dc..aad71bbd580 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5402.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5402.json
@@ -1 +1 @@
-{"ABILIFY": 3.1551888221935767, "GARDASIL": 2.1030527772341507, "LEVOFLOXACIN": 1.996252000307364, "OPTIMARK": 57.46387176007076, "SPINRAZA": 22.321433396426976, "null": 1.272642748520397}
\ No newline at end of file
+{"COMIRNATY": 0.8699781270109439, "TOZINAMERAN": 1.6387810860886909, "VAXZEVRIA": 0.8337743614887914, "null": 1.279516514886861}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5403.json
index 6a1416b6ef9..dd161db73cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5403.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5403.json
@@ -1 +1 @@
-{"COMIRNATY": 1.8191254109907424, "LEVOFLOXACIN": 2.2214024857031087, "NILEMDO": 632.4611504205525, "SHINGRIX": 1.7085103035416591, "SPIKEVAX": 1.793816871040408, "VAXZEVRIA": 1.782891458731355, "null": 1.0971313404966063}
\ No newline at end of file
+{"null": 1.5608023183884372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5404.json
index b66e024ab7b..556b4946f8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5404.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5404.json
@@ -1 +1 @@
-{"ABILIFY": 2.947294244670653, "BYDUREON": 7.991330998583714, "FASLODEX": 2.212891547088625, "GARDASIL": 1.426763537279278, "HUMALOG": 1.2347206395554795, "LYRICA": 4.392064065688369, "OLANZAPINE": 1.5067517509266533, "OPTIMARK": 1.780174623490422, "TOZINAMERAN": 1.2180368026574702, "null": 1.997444538125418}
\ No newline at end of file
+{"ARIPIPRAZOLE": 79.5854412150779, "LEVODOPA": 659.9624101125918, "null": 1.2941955297703815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5405.json
index 07bf1cfa6af..c5c5e08b27e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5405.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5405.json
@@ -1 +1 @@
-{"null": 1.8146962327266931}
\ No newline at end of file
+{"ABILIFY": 2.3294480562906466, "AERIUS": 3.311305008781135, "AMINOSALICYLIC": 0.9384487000349002, "ARIPIPRAZOLE": 4.87036678891114, "ATRIPLA": 0.0407814351653431, "AZILECT": 25.5602279768312, "BEDAQUILINE": 0.924050660509686, "BRINTELLIX": 1.2454001542455582, "BRIVARACETAM": 4.354156378080129, "BRIVIACT": 4.108361007717854, "BUPRENORPHINE": 2.116230316771884, "CANAGLIFLOZIN": 19.78741248109205, "CARBIDOPA": 19.06402630768352, "CELLCEPT": 0.3551571021478445, "CHAMPIX": 3.9217213864839504, "CICLOSPORIN": 0.3672887381782294, "CLOPIDOGREL": 0.3657662262195127, "COMIRNATY": 0.088698183169308, "COMTAN": 27.14727310831451, "CYMBALTA": 2.005647947348569, "DELAMANID": 2.828570343338615, "DULOXETINE": 2.162430506084715, "EBIXA": 10.993170097526582, "ELIQUIS": 0.1282688329418088, "ENTACAPONE": 30.772711995753465, "ENTRESTO": 0.4549949608746814, "ESOMEPRAZOLE": 1.207243971381675, "EVENITY": 1.2974930212690103, "EXFORGE": 0.5642864922129708, "FENTANYL": 0.8546431876560301, "FORSTEO": 0.3173793002481596, "FYCOMPA": 6.176800216476574, "GARDASIL": 0.3276479199228879, "KEPPRA": 3.675190669085266, "LACOSAMIDE": 1.7004806449034184, "LANTUS": 0.1073071341577737, "LATUDA": 3.087308699109023, "LEVETIRACETAM": 3.391483978688039, "LEVODOPA": 34.39880764038122, "LEVOFLOXACIN": 2.510652058993552, "LYRICA": 3.1895343788591046, "MELATONIN": 4.103268460571258, "MEMANTINE": 5.846093479961975, "MIDAZOLAM": 1.0460241124603118, "NEUPRO": 26.680345183922075, "NOXAFIL": 3.4786890835323323, "OLANZAPINE": 3.3034075623418504, "OXYBUTYNIN": 2.3935303441415026, "PEGASYS": 1.0834814088975495, "PEGINTRON": 0.7510109019501972, "PIOGLITAZONE": 65.54495287783573, "PLAVIX": 0.3400987341727673, "POSACONAZOLE": 5.696964522562297, "PREGABALIN": 2.580982864346789, "PROPRANOLOL": 3.543360050268616, "RANEXA": 6.560073753302664, "RANOLAZINE": 5.168106004558706, "RISPERIDONE": 5.512040834318139, "SIFROL": 27.067351593524997, "SPIKEVAX": 0.0961807696652334, "STALEVO": 20.04913758685486, "SUBOXONE": 2.739438946138125, "SUTENT": 0.089347019469401, "TAMIFLU": 6.762625765982687, "TOZINAMERAN": 0.2340971040915657, "VAXZEVRIA": 0.098965006641793, "VFEND": 59.75643232354208, "VIMPAT": 2.800729348188799, "VORICONAZOLE": 44.81446573287334, "XTANDI": 0.8003371766747785, "YESCARTA": 1.264904883577879, "ZYPADHERA": 2.544636836470833, "ZYPREXA": 1.6673416909504095, "null": 2.676650242447612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5406.json
index 41821debbe2..4a7a779d7b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5406.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5406.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.7003232238201416, "COMIRNATY": 1.0300878273804, "COVID19": 9.133361587542094, "FAMPYRA": 2.505136799032439, "GARDASIL": 1.801750209135023, "OPTIMARK": 3.4142423782617337, "SHINGRIX": 1.0172680556502467, "SPIKEVAX": 1.0405415350459757, "TOZINAMERAN": 4.266169355697603, "VAXZEVRIA": 1.111229252604485}
\ No newline at end of file
+{"ABILIFY": 43.50966740688547, "ARIPIPRAZOLE": 10.301920476254049, "CHAMPIX": 5.490112050956109, "COMIRNATY": 0.0804312595154127, "CYMBALTA": 1.4689762782600757, "KEPPRA": 1.5277819418635317, "LEVETIRACETAM": 7.0931842792459125, "LYRICA": 2.994046826317976, "OLANZAPINE": 1.930790553675472, "OXYBUTYNIN": 16.87351985190282, "PEGASYS": 0.7244330924284355, "PEGINTRON": 1.5365378663140898, "SPIKEVAX": 0.0742066988153099, "TAMIFLU": 7.224798356858723, "VAXZEVRIA": 0.0827905621412268, "VFEND": 8.80196688735411, "VORICONAZOLE": 14.197228302801186, "ZYPREXA": 2.657407961420685, "null": 2.565769333646612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5407.json
index f5b0c2245ca..49d2e505bfd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5407.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5407.json
@@ -1 +1 @@
-{"OPTIMARK": 190.51015348922263, "null": 1.009551223095855}
\ No newline at end of file
+{"COMIRNATY": 0.2429171212842952, "VAXZEVRIA": 0.231860616514759, "VFEND": 187.24760436163928, "VORICONAZOLE": 56.02069897689224, "null": 1.0880519849394257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5408.json
index ad27a86f130..f74386f6b75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5408.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5408.json
@@ -1 +1 @@
-{"ABACAVIR": 3.1421042455548305, "ADVATE": 168.5913638164659, "ARIXTRA": 77.7148033002511, "BRILIQUE": 4.548565586421685, "CLOPIDOGREL": 5.12379450647086, "ELIQUIS": 13.860986286403415, "EMICIZUMAB": 222.32659432783367, "ENOXAPARIN": 17.850096392352537, "HEMLIBRA": 368.8851761018944, "KOVALTRY": 231.06293822332853, "LIXIANA": 8.788041150014225, "NOVOSEVEN": 35.37199944726619, "PLAVIX": 9.421461851994469, "XARELTO": 9.088419294248208, "null": 2.192760636749671}
\ No newline at end of file
+{"null": 1.3419956826253077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5409.json
index 1b226ad7b50..69ef0a4c0d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5409.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5409.json
@@ -1 +1 @@
-{"ABATACEPT": 55.36681997060485, "ACETAMINOPHEN": 101.14402644684608, "ADALIMUMAB": 8.775946971078632, "AMINOSALICYLIC": 3.260409262178809, "APREMILAST": 21.68880441626898, "APREPITANT": 10.68946862316932, "ARAVA": 11.258973495805348, "CHLORHEXIDINE": 158.93044170022665, "CIMZIA": 53.28368191580831, "COSENTYX": 4.395911360423021, "ERELZI": 12.987037467407026, "RINVOQ": 1.2264406496826543, "RITUXIMAB": 2.309407024990068, "VIAGRA": 1.236741950004642}
\ No newline at end of file
+{"ABATACEPT": 15.574822213638438, "ACETAMINOPHEN": 36.31596680891196, "ADALIMUMAB": 32.18412249307124, "AMINOSALICYLIC": 1.6449625185112382, "ANAKINRA": 6.200412063138442, "APREMILAST": 13.597033352859649, "APREPITANT": 45.12003483895201, "ARAVA": 57.71539517717878, "ATRIPLA": 0.0309301468494105, "BELIMUMAB": 14.616996410922086, "BENLYSTA": 0.3144741287763346, "CERTOLIZUMAB": 11.065622066544838, "CICLOSPORIN": 0.1685704233310169, "CIMZIA": 4.257824102988123, "COMIRNATY": 0.0113686775966285, "COSENTYX": 1.4975907112479745, "CYMBALTA": 1.2277405340629697, "ENBREL": 1.715536676576943, "ERELZI": 7.814633803474466, "HUMIRA": 1.7022953816823596, "LEFLUNOMIDE": 6.879551589895835, "METHOTREXATE": 0.875197307352619, "MYCOPHENOLATE": 0.7394834141637411, "RITUXIMAB": 2.623776071645356, "SIMPONI": 0.2697338726567601, "TOZINAMERAN": 0.0271021191261112, "VAXZEVRIA": 0.0068349456269215, "XELJANZ": 1.7469591378330342, "null": 0.064897108617918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/541.json
index 1b866c4eada..06fa15be930 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/541.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/541.json
@@ -1 +1 @@
-{"ABATACEPT": 1.3569523270580386, "ABILIFY": 2.3224671878730354, "ACLIDINIUM": 1.1788966875889324, "AERIUS": 1.1359578377649937, "AGOMELATINE": 3.07090957720799, "AIMOVIG": 1.5132178432658026, "ALENDRONATE": 5.083037549053048, "ALISKIREN": 6.056960094960443, "ANORO": 4.185293611286958, "APIXABAN": 2.6870004242757988, "ARIPIPRAZOLE": 1.2626084743165866, "ARSENIC": 5.906182057917096, "ATAZANAVIR": 5.121372204897111, "ATRIPLA": 9.981756945498146, "AZATHIOPRINE": 1.40049589351521, "AZILECT": 1.0956842043637285, "BENZODIAZEPINE": 1.4050394116016447, "BEXTRA": 1.3432064956378422, "BIKTARVY": 1.575889343786762, "BRINTELLIX": 4.619317314188294, "BRIVIACT": 2.6102226933160275, "BUPIVACAINE": 1.381156100502965, "BUPRENORPHINE": 1.6690814837632904, "CANAGLIFLOZIN": 1.1915635692868127, "CANNABIDIOL": 1.5138775428695934, "CARBIDOPA": 1.0187764475512102, "CERTOLIZUMAB": 1.3064149336647557, "CHAMPIX": 4.780971487727802, "CIALIS": 5.495613911796524, "CIRCADIN": 1.5499132210091784, "COMTAN": 1.4999331804780842, "CONTRAST": 2.439137521797732, "CYMBALTA": 5.075860392216875, "DAKLINZA": 1.0803285944108918, "DALIRESP": 1.097837596812468, "DENOSUMAB": 1.8092190698617483, "DESCOVY": 1.4459518994886815, "DOVATO": 1.505463179395801, "DULOXETINE": 1.3627474151350143, "EDURANT": 1.468724935221888, "ELLAONE": 1.1630984959048278, "ENFUVIRTIDE": 2.652666560137375, "ENTACAPONE": 1.6626501923047514, "ESOMEPRAZOLE": 1.013090084781525, "FYCOMPA": 1.6418772920116742, "GARDASIL": 1.1275345924903777, "GLYCOPYRRONIUM": 4.414400461996598, "ILARIS": 4.527741045471823, "INFERGEN": 1.4310421384346663, "INTERFERON": 1.653358392080705, "INVEGA": 1.1809670734762896, "JANUMET": 1.081577413944393, "KAFTRIO": 2.6593063058710427, "KEPPRA": 1.58809870067149, "KUVAN": 2.212205437105592, "LATUDA": 3.307393947750888, "LEVETIRACETAM": 1.042341035719528, "LEVODOPA": 2.382816806697764, "LIRAGLUTIDE": 10.2300050007786, "LURASIDONE": 1.0998457356626896, "LYRICA": 1.2930973413016498, "MELATONIN": 1.4467063144791157, "OLANZAPINE": 1.311051084909719, "OMALIZUMAB": 1.2998331429883694, "OPTIMARK": 6.389095637480471, "OXYBUTYNIN": 1.346723568597071, "OZEMPIC": 1.490836032325177, "PALIPERIDONE": 2.349022033762413, "PEGASYS": 1.4133724753082086, "PEGINTRON": 1.0612872294977465, "PRIALT": 2.998800227940469, "PROLIA": 2.999901777382809, "RANEXA": 1.2532230474605872, "REAGILA": 2.211963657728077, "SAXENDA": 1.0548337562195078, "SEEBRI": 2.7059062670482086, "SEMAGLUTIDE": 1.5234458428024982, "SERTRALINE": 4.85346854084976, "SIFROL": 1.640522962151013, "STRIBILD": 9.74465712378995, "SUBOXONE": 2.198388937451164, "SUBSTANCE": 2.5182975219052115, "SUSTIVA": 1.0700309822880087, "SYCREST": 1.9273379234229864, "TAMIFLU": 1.1661498143298556, "TASIGNA": 3.017489100464697, "TEDUGLUTIDE": 2.4321796793193515, "TESTOSTERONE": 1.3194469348080118, "TIGECYCLINE": 1.0108739041034618, "TIVICAY": 1.1939076520821463, "TRIUMEQ": 2.5126702817908866, "TRUVADA": 8.144784670968768, "VALDOXAN": 2.00040030589495, "VARENICLINE": 2.288763329920857, "VIREAD": 5.714051501038864, "VORTIOXETINE": 2.948017995130213, "WAKIX": 3.897745817976608, "XEPLION": 1.418568787215829, "XYREM": 4.678931396658194, "ZEJULA": 1.4139578627067784, "ZEPATIER": 1.268071965635531, "ZOMETA": 1.6812617295606611, "ZOSTAVAX": 2.8970994780363406, "ZYPADHERA": 2.55641610942508, "ZYPREXA": 1.1402600998340888, "null": 1.2363341547815652}
\ No newline at end of file
+{"null": 0.3842030418334339}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5410.json
index 09404887fe5..c0a0062e2e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5410.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5410.json
@@ -1 +1 @@
-{"TESTOSTERONE": 195.39051143952344}
\ No newline at end of file
+{"CAPECITABINE": 19.580147590345376, "COMIRNATY": 2.254382556236996, "PEGASYS": 2.356356897487794, "SPIKEVAX": 0.7080026038860986, "VAXZEVRIA": 0.3455934651006632, "null": 0.4865115654425807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5411.json
index dc9f44a9c35..6319210a91a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5411.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5411.json
@@ -1 +1 @@
-{"null": 3.1569513411924524}
\ No newline at end of file
+{"AIMOVIG": 1.141913428371983, "ARAVA": 0.1191594115938358, "ATRIPLA": 37.55777014417928, "BUPRENORPHINE": 1.2267050993532167, "ELIQUIS": 0.8843768901311907, "EVISTA": 3.494086252448078, "FORSTEO": 3.896146306799657, "HUMALOG": 0.694455776457752, "IBRANCE": 1.064185195231206, "ILARIS": 147.7608236708438, "KALETRA": 1.863810071596974, "KEPPRA": 0.4964642323179792, "LANTUS": 1.6859592961376992, "STRIBILD": 22.87269317018801, "SUBOXONE": 3.000795013379057, "SUTENT": 0.2496077470187465, "TOZINAMERAN": 0.1142206096212391, "TRUVADA": 18.43026366037598, "VIAGRA": 1.7027918022081687, "XELJANZ": 2.3396441058608803, "ZOSTAVAX": 0.9551261007889832, "null": 0.4594481296792542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5412.json
index 33b6886c2a3..6047e5b80f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5412.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5412.json
@@ -1 +1 @@
-{"COMIRNATY": 1.313985686816855}
\ No newline at end of file
+{"null": 1.3486950296810791}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5413.json
index a021d0483d4..97bd087396a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5413.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5413.json
@@ -1 +1 @@
-{"ZOSTAVAX": 218.53919008947216}
\ No newline at end of file
+{"COMIRNATY": 0.2953262939288593, "SUTENT": 5.538883253152427, "null": 0.6983512116965884}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5414.json
index 8cbe7031a25..0469d5a433c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5414.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5414.json
@@ -1 +1 @@
-{"ABILIFY": 4.703394246839595, "ARIPIPRAZOLE": 8.69442998861359, "BETAFERON": 2.472485330421788, "BRIDION": 7.334475203592546, "BUPIVACAINE": 2.2008937839219853, "BUPRENORPHINE": 1.2686956005006789, "CARBIDOPA": 19.930454164925457, "COMTAN": 33.26051489828492, "CYMBALTA": 1.0523570135024876, "DULOXETINE": 2.400528545968396, "ENTACAPONE": 29.85303263033005, "EXFORGE": 1.21196761463041, "FENTANYL": 5.948349740943895, "FORSTEO": 1.292572070908749, "GARDASIL": 2.295670642580961, "INFANRIX": 3.3394778109955543, "LATUDA": 6.943846111455374, "LEVETIRACETAM": 1.4018862496585969, "LEVODOPA": 16.405095550951703, "MENVEO": 7.146836995226273, "MIDAZOLAM": 5.452083975718347, "NIMENRIX": 1.6142822405667347, "OLANZAPINE": 19.99866088674353, "OPTIMARK": 1.035957983855722, "PALIPERIDONE": 33.29453172440556, "PREGABALIN": 1.9082124397835465, "RENVELA": 157.05964573374231, "RISPERIDONE": 21.58596416363122, "SIFROL": 4.681903116351543, "STALEVO": 16.086162379776695, "SYCREST": 13.567981271452318, "ZONISAMIDE": 14.557648724337986, "ZYPADHERA": 5.275722377631711, "ZYPREXA": 11.520855826122212, "null": 2.3687563847998536}
\ No newline at end of file
+{"OLANZAPINE": 26.64046607765923, "null": 1.0552223260526887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5415.json
index a55e47d0a7d..fe02a340823 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5415.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5415.json
@@ -1 +1 @@
-{"ELIQUIS": 2.366332459798268, "LEVOFLOXACIN": 4.859420718124301, "PLAVIX": 1.417609932341954, "SIMPONI": 1.834852862487593, "TOZINAMERAN": 1.144716487186322, "VIAGRA": 3.566568541899536, "XELJANZ": 4.239719702411953, "null": 2.275859276764477}
\ No newline at end of file
+{"BYDUREON": 5.757316292090104, "CHAMPIX": 3.3336090215114127, "COMIRNATY": 0.6271325909346319, "COSENTYX": 2.189087979730614, "CYMBALTA": 4.058855273990603, "SPIKEVAX": 0.6674660821631996, "TOZINAMERAN": 3.368834741093996, "VAXZEVRIA": 2.82279175504908, "XYREM": 15.869527954881004, "null": 0.8192223485819298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5416.json
index b0a0fc2b041..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5416.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5416.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.2865933745190488, "ABATACEPT": 1.257932141523579, "ABILIFY": 1.078394717165755, "ADENURIC": 1.020794257704903, "AERIUS": 1.657949660970634, "AIMOVIG": 2.9961601927085346, "ALOXI": 2.592170907969974, "APROVEL": 1.7278733011471472, "AUBAGIO": 1.922071499201884, "BEXSERO": 1.001317339143869, "BONVIVA": 1.191531526761385, "BOSULIF": 1.111822858195356, "BOSUTINIB": 2.669409817112228, "BRINTELLIX": 1.3338306961341335, "BUDESONIDE": 1.4786687106793368, "BUPIVACAINE": 3.8031601164019535, "CAPSAICIN": 3.6305471763679775, "CHOLESTAGEL": 10.699498537987708, "CINACALCET": 1.464199996019566, "COAPROVEL": 1.7074393613662608, "COMPRESSION": 15.520951788371654, "COVID19": 1.6598566294314592, "CYMBALTA": 1.1656656230799132, "DASATINIB": 2.109364242685745, "DULAGLUTIDE": 1.043911898515417, "DUORESP": 8.956379816784567, "ELLAONE": 1.6780907422914475, "ENTACAPONE": 1.1400696070240302, "EPOETIN": 1.2203770439157533, "ERENUMAB": 2.310143198258543, "EVENITY": 1.628569341797454, "EVISTA": 4.004184488621846, "EXFORGE": 1.5019059676198276, "FAMPRIDINE": 1.620346259322972, "FAMPYRA": 3.2363984014509555, "FASLODEX": 1.1577414594702886, "FESOTERODINE": 3.0627913244552927, "FIRDAPSE": 2.497313669035319, "FLEBOGAMMA": 1.4578034551838028, "FORSTEO": 4.99039528807127, "GARDASIL": 1.981816332529812, "GILENYA": 2.3840007662375875, "GLIVEC": 1.2105181490101813, "HYDROCHLOROTHIAZIDE": 1.2576779782250227, "HYDROCORTISONE": 1.3987533202567313, "HYQVIA": 1.1332096089174435, "IBRANCE": 1.01383045377277, "IMATINIB": 1.272018541508089, "IMBRUVICA": 2.054079344308416, "INFANRIX": 1.2262653241010582, "INVEGA": 1.4726950672480936, "IRBESARTAN": 1.121338019136651, "KARVEA": 2.107211367889008, "KESIMPTA": 1.020918604340228, "KETOCONAZOLE": 1.6721843617518446, "LATUDA": 1.253410161784692, "LEVODOPA": 1.97648187014602, "LINACLOTIDE": 10.485525791662669, "LUPKYNIS": 1.33581192226947, "LYRICA": 1.558800155826958, "MICARDIS": 1.3429541010573134, "MIMPARA": 2.4120189069019107, "MIRABEGRON": 2.885954298210821, "MOVYMIA": 5.74445811752924, "NEUPRO": 2.701126862665208, "NILEMDO": 13.794132353558789, "NINLARO": 2.0220090332138345, "OCEAN": 8.975409337745328, "OCRELIZUMAB": 3.052193819826842, "OPTIMARK": 7.797043518152326, "ORENCIA": 1.2943303504675228, "OVITRELLE": 1.5024610775098453, "OXYBUTYNIN": 1.860748178573789, "OZEMPIC": 1.0723353368662698, "PERTUZUMAB": 1.2866998270676224, "PLEGRIDY": 1.2439079679452147, "PROLIA": 1.012526667319992, "PROTELOS": 2.08928280948712, "RANEXA": 1.4787389138086426, "REBIF": 1.3161251766112834, "RELVAR": 3.577001240784488, "REVINTY": 3.435648955674925, "REVLIMID": 1.6911339557232727, "RYBELSUS": 1.0756003630102786, "SEMAGLUTIDE": 13.696256817795092, "SIFROL": 1.8846854023508504, "TAGRISSO": 1.1251797548436115, "TASIGNA": 1.3550587425586618, "TECFIDERA": 3.784136065385861, "TELMISARTAN": 1.1308354239249487, "TERIFLUNOMIDE": 1.8115650426943384, "TERIPARATIDE": 2.469262203061878, "TERROSA": 3.495796094787281, "TOZINAMERAN": 1.7724318173444993, "TYSABRI": 3.1020041071496247, "VELMETIA": 1.5085495872379135, "VELTASSA": 1.2317844938063425, "XELJANZ": 1.2975552122611964, "XTANDI": 1.0288564888069636, "XYREM": 1.568020809935134, "ZOSTAVAX": 1.24124627548123, "ZYPADHERA": 1.0393892693581506, "null": 1.2328162997406222}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5417.json
index 219a4ce0534..6bc241e6c06 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5417.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5417.json
@@ -1 +1 @@
-{"ABATACEPT": 14.691566236391054, "ABILIFY": 1.5098185455142168, "ADALIMUMAB": 1.344961113507455, "ALISKIREN": 52.58602668983142, "ARAVA": 21.042189494675814, "ARIPIPRAZOLE": 1.947080105188045, "AUBAGIO": 11.406813967845356, "AVONEX": 47.86737051065053, "BETAFERON": 12.430429347369362, "BUPIVACAINE": 27.123164643549632, "CHLORHEXIDINE": 3.5369934951372546, "CIMZIA": 3.2656670557140512, "CYMBALTA": 3.455007319817792, "DULOXETINE": 1.6530843001623692, "ESOMEPRAZOLE": 6.060979420579608, "EXFORGE": 1.7617572097457634, "FAMPYRA": 32.28110392569897, "FENTANYL": 1.163976314428032, "IBUPROFEN": 3.662268482713934, "IRBESARTAN": 16.24827066279386, "IRON": 10.26859269384046, "JEVITY": 480.8180825742653, "KEPPRA": 2.569772833860457, "KESIMPTA": 8.929703806074848, "LAMIVUDINE": 4.27607627736016, "LEMTRADA": 5.679675875144048, "LINACLOTIDE": 143.13476011750578, "LYRICA": 4.902497859162001, "MIRABEGRON": 25.37170189770751, "NAGLAZYME": 4.511658172215146, "OXYBUTYNIN": 22.681988329537877, "PLEGRIDY": 4.966675769493454, "RENVELA": 228.41890069735095, "TECFIDERA": 27.698310389422748}
\ No newline at end of file
+{"SOLIRIS": 420.2864946301463}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5418.json
index f302b70f0f5..656ba445daa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5418.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5418.json
@@ -1 +1 @@
-{"AIMOVIG": 1.613563410470107, "AUBAGIO": 1.92820878518541, "BENRALIZUMAB": 28.12476520164093, "COSENTYX": 3.952619581341313, "FORSTEO": 1.2526150139537, "HUMALOG": 1.8023580692490255, "IBRANCE": 1.4533594726138572, "METHOTREXATE": 3.617632397031544, "TOZINAMERAN": 1.7022157878141584, "VIAGRA": 2.1026059651859947, "XELJANZ": 4.129407348025351, "ZOSTAVAX": 6.321185694276393, "ZYPREXA": 1.6839782563452708, "null": 1.1194818233526276}
\ No newline at end of file
+{"CICLOSPORIN": 9.699973261541778, "COMBIVIR": 20.665057068757665, "JAKAVI": 9.25034823936566, "PRIVIGEN": 36.92356423182349, "RASBURICASE": 437.31840994707375, "SOLIRIS": 149.62864045334135, "null": 0.8703098202056465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5419.json
index 6aeac6036d6..2ae2d82b801 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5419.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5419.json
@@ -1 +1 @@
-{"COMIRNATY": 2.220914997034065, "COVID19": 1.3012422735774392, "SPIKEVAX": 1.5682850027213897, "VAXZEVRIA": 1.8543376133197285}
\ No newline at end of file
+{"SOLIRIS": 96.7641693229658, "null": 0.7126294333448642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/542.json
index d93d1cb0c82..100832ef4ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/542.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/542.json
@@ -1 +1 @@
-{"ABILIFY": 9.072679408953784, "AMIKACIN": 9.656380191759064, "ARIPIPRAZOLE": 2.504178228267331, "BIKTARVY": 3.982353311394032, "BUMETANIDE": 42.010011533516206, "CHAMPIX": 4.780703734414313, "CYMBALTA": 3.199838694786522, "EPADERM": 445.15862442643135, "FENTANYL": 3.0424164833954426, "GARDASIL": 3.542877015599678, "JANUVIA": 2.6078026570130275, "JARDIANCE": 4.3876998348601335, "KEPPRA": 1.478116678127818, "LEVETIRACETAM": 3.872946813867824, "PEGINTRON": 1.256319180031669, "ZOSTAVAX": 4.29140252280999, "null": 1.494881194169204}
\ No newline at end of file
+{"ABACAVIR": 1.5886654167540808, "ARAVA": 0.3736537473990702, "ASPARAGINASE": 15.8399167838061, "AUBAGIO": 0.7594606433644028, "AVANDIA": 0.930334141727918, "BEDAQUILINE": 3.8008549373551954, "BOSULIF": 3.89819793428598, "BRAFTOVI": 4.011982399454651, "BYDUREON": 2.435030134499657, "BYETTA": 5.246513096176721, "CABOMETYX": 3.0569301310287527, "CELLCEPT": 3.8727576143660993, "CICLOSPORIN": 1.0571168969362927, "COMBIVIR": 3.834942172549373, "COMIRNATY": 0.0474086813426847, "CRIXIVAN": 19.871550489325063, "CYMBALTA": 0.4423539201233808, "CYTARABINE": 1.796547134033389, "DEXAMETHASONE": 1.431978476349394, "EFAVIRENZ": 3.2901406815407586, "ENTRESTO": 0.6910294060924765, "EPIVIR": 7.52748075588499, "EUCREAS": 29.46604981944361, "EXJADE": 1.6611652844363658, "FENTANYL": 1.6043118331183084, "FORXIGA": 1.4254365564159115, "GALVUS": 22.12117026435505, "GLIVEC": 6.833184366588426, "ICLUSIG": 12.601941774524814, "INLYTA": 1.8448965996703028, "IPILIMUMAB": 2.085031515863356, "ISENTRESS": 5.332207763079496, "JANUMET": 8.180354626332832, "JANUVIA": 9.30897824846138, "JARDIANCE": 2.233198366901149, "KALETRA": 3.475488870677262, "KEPPRA": 1.7735542111843874, "KEYTRUDA": 4.406260090593412, "LANTUS": 0.2316750434126263, "MEKINIST": 2.316018006012534, "MERCAPTOPURINE": 7.187581688332613, "NEXAVAR": 11.204096282799698, "NILOTINIB": 9.21739275793892, "OLANZAPINE": 1.2858992359101755, "ONCASPAR": 12.987830257816848, "OPDIVO": 4.95806308725641, "PAZOPANIB": 5.899918398429357, "PEGASYS": 0.2243257719725324, "PEGINTRON": 0.7069219153741487, "PEMBROLIZUMAB": 1.5248230509005685, "PLAVIX": 0.8323767986303845, "RYBELSUS": 5.671405673963641, "SAXENDA": 7.238104714883996, "STIVARGA": 1.4538691946563744, "SUTENT": 1.0296231230133976, "TAGRISSO": 1.8206191673848968, "TASIGNA": 17.280760353425762, "TRULICITY": 11.333830904616011, "VICTOZA": 16.045442514892073, "VIREAD": 4.285906087678335, "VOTRIENT": 3.026984729139077, "XELJANZ": 0.551379004487165, "ZIAGEN": 18.37404941793895, "ZYPREXA": 2.560621699453914, "null": 1.3499587278265104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5420.json
index c982abd68ba..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5420.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5420.json
@@ -1 +1 @@
-{"COMIRNATY": 1.5854793032692325, "NIMENRIX": 11.115284585791168, "SPIKEVAX": 2.872749278880861, "TOZINAMERAN": 2.781660004013172}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5421.json
index 1b918565fbc..048f42cf349 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5421.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5421.json
@@ -1 +1 @@
-{"FENTANYL": 314.2128633340365}
\ No newline at end of file
+{"null": 2.2434296420663644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5422.json
index b00aa1274e7..7b68380f47e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5422.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5422.json
@@ -1 +1 @@
-{"AIMOVIG": 2.227416524332326, "ALEMTUZUMAB": 1.8309023182405448, "BRINTELLIX": 2.632166779774327, "BUPIVACAINE": 3.4367413629941663, "COMIRNATY": 1.327057170864176, "CYMBALTA": 3.067953410420849, "FAMPYRA": 6.347879849822971, "FENTANYL": 1.9327477101758093, "GARDASIL": 2.9787755721043467, "HUMIRA": 3.774451684556418, "JANUVIA": 2.252211803410609, "KEPPRA": 1.359911616635324, "KETOCONAZOLE": 16.48986926511455, "LATUDA": 1.4724469207660709, "LEVOFLOXACIN": 1.1197252425225976, "OPTIMARK": 14.429060955606436, "OXYBUTYNIN": 4.936565431236237, "PREGABALIN": 3.4329693007340705, "SHINGRIX": 1.5213651232804442, "SPIKEVAX": 1.1208754133226435, "SPINRAZA": 3.501321337847505, "TOVIAZ": 4.817108927544359, "TOZINAMERAN": 2.242854824519322, "VAXZEVRIA": 1.0713416237511155, "XYREM": 6.2617087744399615}
\ No newline at end of file
+{"null": 0.9343614962225464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5423.json
index cf484c52a1f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5423.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5423.json
@@ -1 +1 @@
-{"null": 2.154033910838173}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5424.json
index 8be836f77f4..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5424.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5424.json
@@ -1 +1 @@
-{"ABILIFY": 1.2006005604027403, "AIMOVIG": 3.850955047190574, "APIXABAN": 6.9691791912211976, "BEXTRA": 10.747460803875107, "BRIDION": 2.3660244586563715, "BRINTELLIX": 2.1542976905779208, "BRIVIACT": 3.130991179562926, "CELSENTRI": 5.826827876328659, "COMIRNATY": 1.8848659158796577, "CYMBALTA": 2.088657553373812, "DEXAMETHASONE": 1.2002747632768995, "DOXORUBICIN": 1.4134287639072132, "FENTANYL": 1.6012175812629497, "FILGRASTIM": 2.3890805251928344, "FIRDAPSE": 1.635235205853985, "GARDASIL": 3.192684277248285, "INFANRIX": 2.712241082834932, "KEPPRA": 2.3087175839871747, "LACOSAMIDE": 2.033885156191307, "LATUDA": 1.9223750559093356, "LEVETIRACETAM": 2.412541363672651, "LEVOFLOXACIN": 1.9949138720600412, "LOXAPINE": 12.193786743794403, "LYRICA": 1.974826233246767, "MIDAZOLAM": 1.3745215645894917, "OLANZAPINE": 1.121525729057936, "SPIKEVAX": 1.2502450151661593, "SUBOXONE": 1.403706594976311, "SYCREST": 3.480614704247663, "TOZINAMERAN": 2.218725770693595, "TWINRIX": 2.660815696629773, "VAXZEVRIA": 1.056793882185535, "VIMPAT": 1.0949487921217955, "ZYPADHERA": 2.5134405385365186, "ZYPREXA": 1.1933643066092805, "null": 1.160231498417567}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5425.json
index f08847b1a1a..1078a2144a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5425.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5425.json
@@ -1 +1 @@
-{"null": 1.1246274429310863}
\ No newline at end of file
+{"COMIRNATY": 0.5289943370520279, "MMRVAXPRO": 14.447342841230578, "SPIKEVAX": 0.365465116068999, "TOZINAMERAN": 0.8043385359347935, "VAXZEVRIA": 1.7035581246427527, "null": 0.9804122715779534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5426.json
index c2de348906f..34f01d34eea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5426.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5426.json
@@ -1 +1 @@
-{"ABATACEPT": 1.7614013678125209, "ACTOS": 1.1163161794247989, "ALEMTUZUMAB": 1.0641455454839408, "ALISKIREN": 4.501693007252407, "AMINOSALICYLIC": 1.06484124332015, "APIXABAN": 1.6036822080151127, "APREMILAST": 3.1031281553987, "AUBAGIO": 3.0129145779896995, "AVONEX": 2.556692857144089, "BENZODIAZEPINES": 7.167479031125765, "BETAFERON": 3.045618896583388, "BEXTRA": 3.302635869460995, "BONVIVA": 1.1795206748266365, "BORTEZOMIB": 1.0351669222623507, "BRIMICA": 28.959563671864228, "BUPIVACAINE": 2.1269410675909977, "CARBIDOPA": 1.0861672132021634, "COLISTIMETHATE": 3.946657388586083, "COMIRNATY": 1.348735757238558, "CONTRAST": 5.719382308944905, "COVID19": 1.1556110115704754, "CRIXIVAN": 1.2274586451943152, "CUBICIN": 1.666107995758363, "DESLORATADINE": 1.2211294049353083, "DOLUTEGRAVIR": 2.306513241887995, "ENTACAPONE": 1.192797978030626, "ENTECAVIR": 1.0156479776043963, "ENZALUTAMIDE": 2.015200400007508, "ESOMEPRAZOLE": 1.3689512537959705, "EVISTA": 1.3681509646632886, "FAMPRIDINE": 5.029474515911486, "FAMPYRA": 3.7779090083358593, "FASLODEX": 1.1728510852945204, "FIRDAPSE": 5.637877128661003, "FLUCELVAX": 1.1444634028343526, "FORSTEO": 1.5903860943746744, "GARDASIL": 4.461509714841062, "GILENYA": 2.4229811879196266, "HALAVEN": 1.312484755995902, "HEPSERA": 2.943874475443774, "INTELENCE": 1.2423603069832492, "INVEGA": 1.2939422081335372, "IRBESARTAN": 2.541352237650241, "IRON": 1.255444698269472, "KESIMPTA": 2.325459609638912, "LEMTRADA": 2.1324915017030937, "LEVODOPA": 1.1358175732902318, "LEVOFLOXACIN": 1.1031399163980595, "LIXIANA": 1.1980113524671725, "LYRICA": 1.1163179944458137, "MIMPARA": 1.4702654376725153, "MISOPROSTOL": 6.466238838833422, "OCEAN": 10.242025034482634, "OCRELIZUMAB": 3.4830625458159554, "OPDIVO": 1.0435728304738574, "OPTIMARK": 4.3130281200882346, "ORENCIA": 1.979879129117008, "PLEGRIDY": 1.074329716958099, "RANEXA": 1.3819050357953926, "RANOLAZINE": 1.3047286177805557, "REBIF": 1.7005477798185304, "RISPERIDONE": 1.633012964499544, "SHINGRIX": 1.4570475459733476, "SIFROL": 1.3970794255311887, "SILGARD": 3.8414880279171935, "SPINRAZA": 2.584331345227675, "SPIRONOLACTONE": 2.534329561959896, "TECFIDERA": 2.5932401840977333, "TENOFOVIR": 1.1538525261826842, "TERIFLUNOMIDE": 1.518421363756449, "TOZINAMERAN": 1.8816504859090843, "TWINRIX": 2.952869085412212, "VAXZEVRIA": 1.1094419164531273, "XOFIGO": 1.0878512329554555, "XTANDI": 2.495394483175778, "YERVOY": 1.0719689487213078, "ZYPADHERA": 1.8692279662442843}
\ No newline at end of file
+{"SUBOXONE": 40.79009719040551, "null": 2.0287274307096745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5427.json
index ea68c64e334..9af03ac4824 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5427.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5427.json
@@ -1 +1 @@
-{"AFINITOR": 1.060122473603825, "APROVEL": 5.62416008711063, "BENLYSTA": 1.257043114896368, "BENRALIZUMAB": 8.428554414547074, "BONVIVA": 3.539006726393864, "BUPIVACAINE": 2.1119878155979475, "BYETTA": 1.143941496250248, "CHAMPIX": 2.6063396790172555, "COMIRNATY": 1.460701084049933, "COSENTYX": 1.4953443280921193, "COVID19": 1.5946711404912115, "DEXAMETHASONE": 1.3384851721247746, "ENTYVIO": 1.788290615432086, "ESBRIET": 1.261357576043668, "EVENITY": 1.905224395247252, "FASLODEX": 3.363373594974164, "FIRDAPSE": 3.727798313730399, "FORSTEO": 2.6651434596131174, "GARDASIL": 1.465382942251264, "HEPSERA": 6.291496500752625, "IBRANCE": 3.2021676715538043, "INLYTA": 1.3683316263874838, "KAFTRIO": 1.8456745561596, "KISQALI": 1.996868982313528, "LEFLUNOMIDE": 4.726300449926645, "MEPOLIZUMAB": 8.132743216889573, "NEULASTA": 2.519130174600301, "OXYBUTYNIN": 13.129472780261862, "PANTOPRAZOLE": 1.4376406413427676, "SHINGRIX": 1.617376644015158, "SPIKEVAX": 1.242713530977213, "SUTENT": 1.1989182541057104, "TOZINAMERAN": 2.2837707447358224, "VOTRIENT": 1.4393363029008317, "XELJANZ": 1.0937513654089448, "XOFIGO": 2.9521658499840675, "XOLAIR": 1.093665986899721, "XTANDI": 1.931636994236388, "ZARZIO": 11.490152077859197, "ZOSTAVAX": 1.5471511624387548}
\ No newline at end of file
+{"BUDESONIDE": 15.847504722766072, "CICLOSPORIN": 11.392294542520396, "null": 3.584021902723622}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5428.json
index fd23a97a662..c1d648271fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5428.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5428.json
@@ -1 +1 @@
-{"ABATACEPT": 94.34284544781342, "ADALIMUMAB": 27.88049298956776, "ENBREL": 25.20263751362485}
\ No newline at end of file
+{"ADALIMUMAB": 0.2980766211389203, "AFINITOR": 0.1846373991278481, "AIMOVIG": 1.958736186287802, "APIDRA": 0.5098335291475949, "AUBAGIO": 0.476916430615118, "AVAMYS": 0.8977802240870258, "BENLYSTA": 1.2820093806333253, "BETMIGA": 1.4746841534527872, "BOTULINUM": 74.08518967532446, "BRILIQUE": 0.6119667796956536, "BRINTELLIX": 2.297322009021695, "BUDESONIDE": 0.6541265076131019, "BYDUREON": 1.3285676834438984, "CHAMPIX": 1.153187331265402, "CIMZIA": 0.0946642933130525, "CLOPIDOGREL": 0.5681857144580527, "COMIRNATY": 2.040496776878699, "COSENTYX": 0.2213307853294623, "CYMBALTA": 0.7715370017178276, "EBIXA": 3.262171527426476, "ELIQUIS": 0.7434546239746237, "ENTRESTO": 0.2057555552854854, "ENTYVIO": 0.4161795764766812, "ERENUMAB": 4.594867889050179, "EXFORGE": 1.3532582750508224, "FAMPYRA": 0.802194972948992, "FASENRA": 0.498338400671365, "FIRDAPSE": 1.6937509172686256, "FORSTEO": 1.6817014942328277, "FORXIGA": 0.3423683880660075, "GARDASIL": 0.7566104624937625, "HUMALOG": 0.3453181356350306, "HYDROCORTISONE": 0.6710370783320446, "IBRANCE": 0.6171268298194802, "INLYTA": 0.4033179062150808, "IRON": 5.172275441735192, "JAKAVI": 0.5860248321873551, "JARDIANCE": 0.211406536275822, "KAFTRIO": 1.023353812952602, "KEPPRA": 0.4871478763565388, "KEYTRUDA": 0.0952034782506985, "LANTUS": 0.2810686561393929, "LATUDA": 0.8843217311693808, "LEVOFLOXACIN": 0.342316290577601, "LIXIANA": 1.5208252664582091, "LYRICA": 0.5425042056912552, "MELATONIN": 1.5894868507166902, "MEPOLIZUMAB": 2.1443384261371845, "NIMENRIX": 0.9077417370403073, "NUCALA": 0.338906328454152, "OCRELIZUMAB": 1.2894108016280794, "OLANZAPINE": 0.2034674421893557, "OMALIZUMAB": 0.3006649142058957, "OPSUMIT": 0.3707611439408621, "PANTOPRAZOLE": 0.5622145589675174, "PEGASYS": 0.343988024187502, "PLAVIX": 0.1575345398474806, "RASILEZ": 1.5817141336224074, "RELVAR": 1.2065461809919331, "ROACTEMRA": 0.3476226227494911, "SHINGRIX": 0.7432228800891347, "SIFROL": 1.5868259026629108, "SILDENAFIL": 0.8956065721784184, "SPIKEVAX": 1.4798637080018435, "STELARA": 0.5592701541939754, "SUTENT": 0.2269834900851896, "TOZINAMERAN": 2.4908562876262814, "TRELEGY": 0.3801215727275213, "TRULICITY": 0.3490961561474057, "VAXZEVRIA": 2.085345455227328, "VIAGRA": 0.5703433122355391, "XELJANZ": 0.4769277055000631, "XOLAIR": 0.5664651950626121, "XTANDI": 0.7473062772286898, "ZOSTAVAX": 0.2627739352658756, "ZYPREXA": 0.3291814676435202, "null": 0.7130186145320031}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5429.json
index f87641301d9..c80c4893e64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5429.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5429.json
@@ -1 +1 @@
-{"AUBAGIO": 1.208867896581785, "BENLYSTA": 1.7141309443425965, "COMIRNATY": 1.3802086328415928, "COSENTYX": 3.5365620806802784, "ENBREL": 5.877989575141969, "FASLODEX": 1.47075652647888, "FORSTEO": 2.404211225708773, "FULVESTRANT": 3.443028425450144, "HUMIRA": 1.5413054678830798, "IBRANCE": 1.0680271496532816, "IRBESARTAN": 9.953365071502423, "LEVOFLOXACIN": 1.1267095145541062, "LYRICA": 1.0325382028393315, "NIMENRIX": 1.107301837831561, "OXYBUTYNIN": 4.386520725029194, "RINVOQ": 1.847735615240256, "SHINGRIX": 1.038667865538316, "SPIKEVAX": 1.4054780175655162, "SUBOXONE": 1.2675919194721743, "TOZINAMERAN": 1.926391331223405, "VAXZEVRIA": 1.195748980896622, "XELJANZ": 2.547961877215986, "ZOSTAVAX": 1.1063345004403122}
\ No newline at end of file
+{"ABILIFY": 1.0712619253146431, "ADEMPAS": 3.407176019874939, "ADVATE": 11.662746173364592, "AIMOVIG": 0.6530603986677425, "ALEMTUZUMAB": 0.8894915922191609, "ANORO": 1.7539659896842086, "APIDRA": 0.5727090803734078, "APIXABAN": 0.5654401400228051, "ARIPIPRAZOLE": 0.7260258401195346, "AUBAGIO": 2.1130102448858263, "BENLYSTA": 0.5918094610944916, "BOSULIF": 1.621257115697406, "BRINTELLIX": 0.5157213110678415, "BYDUREON": 0.8479298008914425, "BYETTA": 1.2548560810275216, "CARBIDOPA": 5.487906837216118, "CELLCEPT": 0.4001586565655147, "CHAMPIX": 0.7445249793470963, "CIMZIA": 0.3054061030550997, "CLOPIDOGREL": 1.08169299735461, "COAPROVEL": 1.4520368869897209, "COMIRNATY": 0.2201662890129621, "COSENTYX": 0.2781726300736946, "CYMBALTA": 1.930492330052184, "CYTARABINE": 1.3138509374712095, "ELIQUIS": 5.416980855713284, "EMICIZUMAB": 40.897408721612, "ENBREL": 0.352995223786558, "ENTRESTO": 2.1249779247579745, "ESBRIET": 1.4885440075421486, "EVISTA": 2.806256227341833, "EXFORGE": 0.9685176218139854, "EXJADE": 0.638232961052839, "FAMPYRA": 2.1836017515404404, "FENTANYL": 0.5028454409024913, "FIRDAPSE": 3.303139302154598, "FORSTEO": 2.017524715744212, "FYCOMPA": 6.676504151030104, "GARDASIL": 5.776231490997012, "HEMLIBRA": 32.61547141284012, "HIZENTRA": 1.9932561750538296, "HUMALOG": 3.5913628101548296, "HUMIRA": 0.6892741872964931, "HYDROCORTISONE": 1.271927711083389, "IBRANCE": 1.106122585142282, "INLYTA": 1.0372089171205363, "INSULIN": 0.8918789692996599, "JAKAVI": 1.0477841473830989, "JANUMET": 0.986169111934064, "JANUVIA": 1.2732061399191243, "JARDIANCE": 0.5343858618064528, "KEPPRA": 3.2501384298992724, "KEYTRUDA": 0.1455901427417454, "LANTUS": 1.988934286521682, "LATUDA": 2.049495255294012, "LEVEMIR": 1.2527841671330255, "LEVETIRACETAM": 0.7864700476199503, "LYRICA": 2.987607146003576, "MEKINIST": 0.6404243803180714, "MENVEO": 5.515812438376587, "MICARDIS": 1.2327049031050428, "MIDAZOLAM": 1.1903480109743736, "NAGLAZYME": 4.805716466873002, "OLANZAPINE": 0.9220334284904284, "OPSUMIT": 2.100899907781085, "PEGASYS": 0.6733212935674052, "PEGINTERFERON": 0.7929412942223778, "PEGINTRON": 1.254530146136981, "PLAVIX": 2.066906140273, "REVATIO": 3.4570171238113585, "RUBRACA": 1.4706571955082617, "SAXENDA": 0.6797058935965894, "SHINGRIX": 0.8807838163443906, "SIMPONI": 0.5189234566246982, "SOLIRIS": 0.6267902320496168, "SOMATROPIN": 4.360510550601289, "SPIKEVAX": 0.6159210593287016, "STALEVO": 1.9633483417310411, "STELARA": 0.4989012076993161, "SUBOXONE": 2.8682635646402423, "SUTENT": 0.9216761091589716, "TAGRISSO": 0.9387865105748516, "TAMIFLU": 0.8252391869448522, "TOVIAZ": 2.3192771840047235, "TOZINAMERAN": 1.233461037920529, "TRACLEER": 1.170709957948665, "TRELEGY": 1.3107179836432858, "TRULICITY": 1.04943386603638, "VAXZEVRIA": 0.1319867066569665, "VELTASSA": 1.9710157027149964, "VIAGRA": 1.6501226123231696, "VIMPAT": 5.443299115673567, "XARELTO": 1.0832614337139328, "XELJANZ": 0.9772978478116224, "XTANDI": 2.023987785892876, "XYREM": 2.781333811644462, "ZOSTAVAX": 0.9639519013418684, "ZYPREXA": 1.518401669381294, "null": 1.5420635838539414}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/543.json
index fb8e735ed0e..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/543.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/543.json
@@ -1 +1 @@
-{"GARDASIL": 52.9345240341982}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5430.json
index c84bb8678ae..0d52af8b1b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5430.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5430.json
@@ -1 +1 @@
-{"ABATACEPT": 1.3350966837138605, "ACETYLSALICYLIC": 92.05833702424012, "ADALIMUMAB": 3.239464489598455, "ANAKINRA": 47.896622089975885, "ARAVA": 5.053214500409497, "AUBAGIO": 4.455088440664124, "CELECOXIB": 2.941449501240041, "ENBREL": 6.081405235345452, "FAMPYRA": 23.05037899143051, "FASLODEX": 1.2412931037809716, "HUMALOG": 2.0102312679837926, "HUMIRA": 3.4607610254680607, "IBRANCE": 1.1327251324197634, "LANTUS": 1.0322406113132072, "LEMTRADA": 1.8442737362951251, "LYRICA": 1.9476994992744296, "METHOTREXATE": 1.2937440219454668, "OPTIMARK": 2.254740944591571, "PEGINTRON": 3.5864156883165847, "PLEGRIDY": 9.79984424322577, "REVATIO": 3.579451703223251, "RINVOQ": 4.766405364026517, "SUBOXONE": 1.6851917368427167, "TOVIAZ": 8.347428426560988, "TRULICITY": 1.2355677757322636, "VIAGRA": 9.391475175348328, "XELJANZ": 3.435690119569411, "ZOSTAVAX": 1.6260608191643675}
\ No newline at end of file
+{"VAXZEVRIA": 2.0638156604354325, "null": 0.438944582825541}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5431.json
index 6d58b28d028..4712c1c4b46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5431.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5431.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 24.027052810713418, "null": 7.603510004502053}
\ No newline at end of file
+{"ARIPIPRAZOLE": 34.14094511770808, "COMIRNATY": 0.4545695082863333, "CYMBALTA": 1.920439214912903, "KEPPRA": 4.237552567148993, "SPIKEVAX": 0.3257133660562037, "TOZINAMERAN": 0.8926851404101308, "VAXZEVRIA": 0.530313007898538, "null": 1.4218852318844852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5432.json
index 7c7d99797f1..c9dd3e15c00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5432.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5432.json
@@ -1 +1 @@
-{"ABATACEPT": 8.044003778959254, "ACLASTA": 5.539037358927272, "ADALIMUMAB": 3.177389417540368, "AFINITOR": 2.061481348245846, "AMINOSALICYLIC": 1.3707713241348347, "ANAKINRA": 16.16478557257648, "APREMILAST": 9.06383803522002, "ARAVA": 4.061352684228294, "AZACITIDINE": 1.2483418660791756, "AZATHIOPRINE": 1.713977479676886, "BONVIVA": 4.984593009101706, "CIMZIA": 1.2274108352758364, "COMIRNATY": 2.1239748392696964, "COSENTYX": 3.9722130393392767, "CYMBALTA": 2.1400790250723007, "DASATINIB": 2.4133468589826985, "DONJOY": 599.3138099904689, "DULOXETINE": 1.9238730426259476, "ENBREL": 7.100525542067282, "ESMYA": 3.7393132635546578, "EVEROLIMUS": 1.984656987261422, "EVISTA": 1.6020580975088965, "FAMPYRA": 1.1496771038889095, "FASLODEX": 3.331166283301034, "FILGRASTIM": 1.6369336428017278, "FIRDAPSE": 1.993612497053276, "FORSTEO": 1.4216777120130546, "FULVESTRANT": 1.0029872331886998, "GARDASIL": 1.082796011469023, "HUMIRA": 2.216274590322169, "IFLOW": 661.1240093632636, "LEFLUNOMIDE": 2.3547135992354824, "METHOTREXATE": 1.0982093867585097, "NEULASTA": 2.425379675115351, "OMALIZUMAB": 1.4175509065229748, "PAIN": 135.39174423901332, "PANTOPRAZOLE": 1.2803706292480144, "RITUXIMAB": 1.651671606841409, "SPRYCEL": 1.515862940090674, "TASIGNA": 1.5413753787465303, "VAXZEVRIA": 1.573331294006793, "VORICONAZOLE": 2.3127547665720374, "XOLAIR": 1.0543524956795478, "ZOSTAVAX": 1.0493546137674172}
\ No newline at end of file
+{"ABACAVIR": 0.7621491917830786, "ABASAGLAR": 0.2294547663641826, "ABATACEPT": 0.2006499604306434, "ABILIFY": 0.1075250852951366, "ACETYLSALICYLIC": 0.6508100631255263, "ACLASTA": 0.2526180791127667, "ACLIDINIUM": 0.1090693426503073, "ACTOS": 0.148185918957791, "ACTRAPID": 0.0786659004421805, "ADALIMUMAB": 0.3055262017438216, "ADCIRCA": 0.9919109356586856, "ADEMPAS": 0.988044714847062, "ADENURIC": 0.3063127790045887, "ADVAGRAF": 0.2979434766328134, "ADVATE": 0.148304481735182, "AERIUS": 0.6112448716472133, "AFINITOR": 0.1803446836349673, "AFLIBERCEPT": 0.1457721375331909, "AGOMELATINE": 0.289113630191968, "AIMOVIG": 0.6960727968781486, "ALDARA": 0.7565220209654426, "ALEMTUZUMAB": 0.3546420133762249, "ALIGN": 1.0145847013190408, "ALIMTA": 0.0771727186962423, "ALISKIREN": 0.5602274142667985, "ALL": 0.2167050687609641, "ALLI": 0.337332217308829, "ALPELISIB": 0.1575223862192484, "AMBIRIX": 1.132140914339689, "AMBRISENTAN": 0.746927752920361, "AMGEVITA": 0.3702206465146298, "AMIKACIN": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5433.json
index 3b3e73e25e4..64e6540c01b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5433.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5433.json
@@ -1 +1 @@
-{"ABATACEPT": 2.4516636390671667, "ABILIFY": 1.3656606021059443, "ADALIMUMAB": 2.7490435485845675, "ADCIRCA": 1.092551560534602, "AIMOVIG": 1.039772677928591, "ANAKINRA": 1.3184568153091183, "APREMILAST": 10.823090623686443, "ARAVA": 6.168357153468685, "AUBAGIO": 1.9000985062047604, "AZATHIOPRINE": 2.319022258181382, "AZILECT": 1.36163262434091, "BELIMUMAB": 1.6171188408081665, "BENLYSTA": 1.1778886440802103, "BETAFERON": 1.161589724224461, "BONVIVA": 2.4781772130800053, "BRIDION": 1.6235935969003692, "BUDESONIDE": 1.4072988709669838, "CARBIDOPA": 2.4880036206940472, "CELECOXIB": 1.1494257290773096, "CERTOLIZUMAB": 4.0847468496939445, "CIMZIA": 1.9423988643423564, "COMIRNATY": 1.075103479288929, "COMTAN": 3.2392747716831938, "CONTRAST": 6.8184519483309085, "COSENTYX": 5.495285825912794, "COVID19": 1.5551096114996577, "ENBREL": 6.346298454153795, "ENTACAPONE": 3.854784034248912, "ERELZI": 11.603371470683705, "ERENUMAB": 1.7287830574465508, "ETANERCEPT": 4.673732889500736, "FAMPRIDINE": 2.989313744667246, "FAMPYRA": 1.6567173170738492, "FLUCELVAX": 2.069948152290699, "GARDASIL": 1.7571685208356744, "GILENYA": 2.636150437711364, "HIZENTRA": 1.2264902317897348, "HUMIRA": 3.5404132279728797, "INFLECTRA": 1.8927202647752883, "INVEGA": 2.40739109565096, "KETOCONAZOLE": 2.535045555170216, "KIOVIG": 1.0729005357837649, "LATUDA": 2.049140616977808, "LEFLUNOMIDE": 7.059125854719007, "MAYZENT": 12.858548505148864, "MENVEO": 1.9496676955445371, "METHOTREXATE": 2.890659585694976, "NEVANAC": 2.323828710187012, "NIMENRIX": 2.705844199530369, "OCRELIZUMAB": 2.34470884066925, "OPTIMARK": 6.461734883825051, "PRIVIGEN": 3.0584277161268454, "REAGILA": 3.2188980435166887, "RENVELA": 25.34841798684741, "RITUXIMAB": 1.4117783952030554, "SIFROL": 1.4519383479763075, "SIMPONI": 1.597849582600648, "SPIKEVAX": 1.2183057073701096, "SPINRAZA": 1.0611971208131443, "STALEVO": 3.3576030236252605, "SYCREST": 1.5643016951369078, "TOZINAMERAN": 1.843648543511688, "TWINRIX": 1.3518881130696925, "VAXZEVRIA": 1.0044367971439605, "XELJANZ": 3.2104209048186707, "ZYPADHERA": 1.184501564002475}
\ No newline at end of file
+{"null": 1.1187061430061025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5434.json
index 8803405703f..a935e865730 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5434.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5434.json
@@ -1 +1 @@
-{"ABILIFY": 6.850632482819692, "ARIPIPRAZOLE": 20.359318302123377, "KEPPRA": 5.781697817227845, "OLANZAPINE": 20.679661105866614, "SUTENT": 1.8469122676722136, "TOZINAMERAN": 1.339563082819536, "XELJANZ": 2.483974516899671, "ZYPREXA": 7.974915111242755, "null": 1.5946485970797686}
\ No newline at end of file
+{"COMIRNATY": 0.5430882549375871, "null": 1.1560916602842155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5435.json
index 4c27e50ae29..4447aa0892d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5435.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5435.json
@@ -1 +1 @@
-{"ALDARA": 1.2162465327275878, "BEMPEDOIC": 13.98203209107439, "BONVIVA": 1.674698758017511, "CERVARIX": 1.1377930435104695, "CHOLESTAGEL": 3.055253169759368, "COMIRNATY": 3.426081177760506, "COVID19": 4.35125107258701, "ELASOMERAN": 1.3712330192646631, "FLUCELVAX": 1.5091114772903833, "JCOVDEN": 2.150954659312319, "LEQVIO": 3.369100339840505, "NILEMDO": 14.417780807854356, "NIMENRIX": 1.0877225971569906, "NUSTENDI": 4.250344691869928, "PRALUENT": 2.5189684738246845, "REPATHA": 2.185215636451157, "SCEMBLIX": 1.41113716177195, "SEMAGLUTIDE": 2.0151036703337253, "SHINGRIX": 1.1331992187794668, "SPIKEVAX": 3.479196381544742, "TOZINAMERAN": 1.1404463913794003, "TREDAPTIVE": 5.535939184449084, "VAXZEVRIA": 3.301187984473398, "ZIAGEN": 1.5078070576161609}
\ No newline at end of file
+{"COMIRNATY": 0.6565054806932794, "VAXZEVRIA": 1.5364953496581475, "null": 1.0955434952890146}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5436.json
index 5e3ec6994cd..b380fb011b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5436.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5436.json
@@ -1 +1 @@
-{"COMIRNATY": 3.755795029612401}
\ No newline at end of file
+{"OPSUMIT": 116.40019806549728, "TRACLEER": 153.6498255998542, "null": 0.515770594264304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5437.json
index 8b631a509e5..f733f02e757 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5437.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5437.json
@@ -1 +1 @@
-{"AXITINIB": 12.11973995023847, "CELLCEPT": 2.7640399540590344, "DARBEPOETIN": 101.68476605696192, "ELIQUIS": 1.0486022285504364, "FIRDAPSE": 6.813466680856688, "GARDASIL": 1.396141217148646, "HUMAN": 3.788017304848753, "HUMIRA": 2.363821166964887, "INLYTA": 2.257196993466269, "IPILIMUMAB": 22.77116436963525, "KEYTRUDA": 29.305083589509465, "LEVOFLOXACIN": 1.1648707740869495, "MELATONIN": 11.712335951291577, "OPDIVO": 22.258222480237016, "PEGASYS": 1.2496690715676513, "PEGINTERFERON": 2.538010425065013, "PEGINTRON": 1.59773931633655, "PEMBROLIZUMAB": 26.215648034731014, "PRIVIGEN": 2.5122200044316805, "RITUXIMAB": 2.3522965180062028, "SOLIRIS": 43.35999711736493, "STELARA": 1.4639621188425809, "XOLAIR": 1.1201064247440096}
\ No newline at end of file
+{"null": 2.6954849018187272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5438.json
index cd67b0a9174..b8bf4731e7e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5438.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5438.json
@@ -1 +1 @@
-{"KEYTRUDA": 9.84488804159934, "PEMBROLIZUMAB": 30.418324473380853, "SOLIRIS": 157.05129187414656}
\ No newline at end of file
+{"ALISKIREN": 9.771826857909712, "ATRIPLA": 0.2746926079142602, "CELLCEPT": 1.6863809778722227, "COMBIVIR": 5.062314841351838, "COMIRNATY": 0.0911757239325128, "IBUPROFEN": 2.8984929862073123, "KEPPRA": 1.909910089696061, "LANTUS": 0.570058168303751, "NORVIR": 22.051945591775198, "STELARA": 0.9343535256141166, "SUBOXONE": 3.264566365973748, "SYNAGIS": 14.403515377699994, "TOZINAMERAN": 0.3020021007343543, "TRACLEER": 2.1924865879802984, "VAXZEVRIA": 0.09314375499192, "ZYPREXA": 1.0009403870644469, "null": 6.035244917987387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5439.json
index 425ee16f0d2..b133aa1f184 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5439.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5439.json
@@ -1 +1 @@
-{"FIRDAPSE": 594.6413670970958, "IPILIMUMAB": 30.15867478453428, "KEYTRUDA": 15.890342360489829, "OPDIVO": 9.244769872030815, "PEMBROLIZUMAB": 33.76937177007655}
\ No newline at end of file
+{"ENTRESTO": 30.516256251498195, "null": 0.4732727925385979}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/544.json
index bed8251b91f..9f1dfa34567 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/544.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/544.json
@@ -1 +1 @@
-{"null": 3.037725845126247}
\ No newline at end of file
+{"ENBREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5440.json
index 97d63eefa21..e349eceacff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5440.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5440.json
@@ -1 +1 @@
-{"AMIKACIN": 51.05499789923144, "APIXABAN": 17.74908051016117, "CANAGLIFLOZIN": 180.1345642652421, "CICLOSPORIN": 7.85459758922767, "INVOKANA": 42.24188768373045, "JAKAVI": 9.09226126479271, "LAMIVUDINE": 38.404652003389984, "NUCALA": 5.738034805515741, "XELJANZ": 2.372770725834075}
\ No newline at end of file
+{"CLOPIDOGREL": 8.190638656809508, "COMIRNATY": 0.1844796665064109, "ENTRESTO": 56.69108818540332, "SPIRONOLACTONE": 91.6063468955274, "TAGRISSO": 28.31332695155776, "null": 0.4352020731547634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5441.json
index 10ecfe8be15..84b11435011 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5441.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5441.json
@@ -1 +1 @@
-{"AMIKACIN": 644.3524522687882, "PEGINTERFERON": 39.40274218024246}
\ No newline at end of file
+{"BYDUREON": 6.328616036708412, "COMIRNATY": 0.5907077986980233, "OCRELIZUMAB": 19.30133170341808, "SPIKEVAX": 2.496412280214256, "STELARA": 3.1358598197620835, "TOZINAMERAN": 2.2240491234225117, "VAXZEVRIA": 14.527354120125237, "null": 0.0633165611824553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5442.json
index a49b5bce33c..9a16b6b65dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5442.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5442.json
@@ -1 +1 @@
-{"ABACAVIR": 4.033079831110975, "AMIKACIN": 208.6702244361007, "ATAZANAVIR": 18.57641566219981, "BENRALIZUMAB": 30.621198959091775, "BIKTARVY": 15.940841457075749, "CICLOSPORIN": 4.219271145249596, "DESCOVY": 39.47881318032175, "EFAVIRENZ": 23.09017350876748, "EMGALITY": 846.56413802355, "EPIVIR": 22.917102689188237, "JAKAVI": 5.453006197334908, "KALETRA": 7.528109052886492, "LAMIVUDINE": 19.15581025306196, "MEPOLIZUMAB": 17.91529315822425, "MYCOPHENOLATE": 13.936788747017497, "NORVIR": 13.744392662934828, "NUCALA": 5.361211638852794, "PEGASYS": 1.390121921238805, "TRELEGY": 9.264988059016911, "XELJANZ": 1.4239012193605862, "null": 1.065793609494716}
\ No newline at end of file
+{"AIMOVIG": 2.8710208127939176, "COMIRNATY": 1.1567927250753092, "CYMBALTA": 0.7927950529972726, "DOXORUBICIN": 6.062422331254474, "ELIQUIS": 1.5450275301785832, "ENTRESTO": 4.122690429358669, "FILGRASTIM": 11.977554611581343, "GARDASIL": 0.8958144471509439, "IBUPROFEN": 1.9021206578714145, "KEYTRUDA": 0.9229170463567512, "LEMTRADA": 3.131755703715311, "LEVOFLOXACIN": 1.679070668006549, "SPIKEVAX": 0.7873894112447104, "TOZINAMERAN": 4.573050528565459, "VAXZEVRIA": 0.9894577480233148, "XOLAIR": 0.872730193789185, "null": 0.981159316617372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5443.json
index 05583f881a3..83c72539ca8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5443.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5443.json
@@ -1 +1 @@
-{"ASPARAGINASE": 560.566896846649, "CICLOSPORIN": 26.67661126509181, "MYCOPHENOLATE": 40.13034780871492}
\ No newline at end of file
+{"ABILIFY": 0.8112932487774247, "ACLASTA": 7.617924085514173, "AFINITOR": 1.2313028279823317, "AIMOVIG": 0.6914164333401962, "ALEMTUZUMAB": 2.553050430881372, "ANAKINRA": 2.187898082799443, "APIXABAN": 0.8901887558518331, "ARAVA": 0.2174582278072958, "ARIPIPRAZOLE": 0.726174114324756, "AUBAGIO": 0.4251011337663026, "AVANDIA": 0.5964081122610678, "BENLYSTA": 0.4167707183203117, "BOSULIF": 1.1417310859677614, "BRIDION": 4.839388247126134, "BRILIQUE": 2.030605061579656, "BRINTELLIX": 0.411234947682187, "BUDESONIDE": 0.4383402731524834, "BUPIVACAINE": 2.054904534331672, "CAPECITABINE": 1.043397415306991, "CELECOXIB": 1.2995293233833385, "CHAMPIX": 0.3957790941867228, "CHLORHEXIDINE": 0.839096882119944, "CICLOSPORIN": 0.4995452724669815, "CLOPIDOGREL": 1.1823076844772913, "COMIRNATY": 0.5329765342117698, "CORTICOSTEROIDS": 10.77143943380814, "COSENTYX": 0.4719198706987459, "CYMBALTA": 0.208432088576933, "DEXAMETHASONE": 1.2622954400469546, "DEXMEDETOMIDINE": 5.665609169208732, "DULOXETINE": 1.3913933383905384, "ELIQUIS": 1.0900825125069575, "ENBREL": 0.6608910329703792, "ENTRESTO": 4.860297003144631, "ENTYVIO": 0.6736464708539668, "ESBRIET": 1.04282173047951, "ESOMEPRAZOLE": 2.106462965639234, "EXFORGE": 2.50237276481534, "FENTANYL": 3.090341836508568, "FORSTEO": 0.4143790852068427, "GARDASIL": 0.7265031973210954, "HARVONI": 0.7205508974728214, "HUMALOG": 0.8419220690090514, "HUMAN": 1.5454252243944766, "HUMIRA": 0.5038598589602906, "IBRANCE": 0.4206781773310312, "IBUPROFEN": 0.3902940562573615, "ILARIS": 41.69282799220811, "INFLECTRA": 10.52961376324002, "INFLIXIMAB": 2.120600863498509, "INLYTA": 0.491825771202817, "INSULIN": 0.6594740359357512, "IRBESARTAN": 1.6296011925425915, "IRON": 3.32877661780945, "JANUVIA": 0.4131893980972694, "JARDIANCE": 0.8353827317888718, "KALETRA": 0.7428692151121867, "KEPPRA": 0.550727171125033, "KEYTRUDA": 0.1629184100015104, "LANTUS": 0.4908223268723408, "LEFLUNOMIDE": 2.0844129315542586, "LEMTRADA": 3.255732245459075, "LEVETIRACETAM": 0.4477084811051529, "LEVOFLOXACIN": 0.4174776715249065, "LYRICA": 1.575987727132517, "MENVEO": 3.1463137600313003, "MEPOLIZUMAB": 0.5193584015892931, "METHOTREXATE": 3.821216512204815, "MICARDIS": 2.7862177420561807, "MIDAZOLAM": 4.694825161932841, "MULTAQ": 10.769817329415172, "NUCALA": 0.4133055377094259, "OCTREOTIDE": 11.257876641843296, "OFEV": 0.9969479662685644, "OLANZAPINE": 1.0092097038676702, "OMALIZUMAB": 2.4739447079321923, "OPSUMIT": 1.1613289351531837, "ORENCIA": 7.600888751752111, "PANTOPRAZOLE": 4.516047920148172, "PEGASYS": 0.3685890158761442, "PEGINTRON": 0.4913368978766714, "PLAVIX": 0.6156694660859169, "PRIVIGEN": 1.166109938660016, "PROPRANOLOL": 12.260831765631924, "RANOLAZINE": 5.70689113614341, "RAPISCAN": 22.20754325626869, "RASILEZ": 2.701663508521147, "REGADENOSON": 69.67538769661037, "REMICADE": 1.5130835885015417, "REVATIO": 1.1801697054737226, "RITUXIMAB": 7.335827436130102, "SILDENAFIL": 1.9908367603955428, "SOMAVERT": 15.84040714212818, "SPIKEVAX": 0.2945506680176882, "SPINRAZA": 1.3423464581222238, "SUBOXONE": 0.9669501855180792, "SUFENTANIL": 1.8949720608422933, "SUTENT": 0.8285699901067426, "SYNAGIS": 0.8412529381643635, "TAMIFLU": 0.5407161638754969, "TASIGNA": 0.7533667207077922, "TELMISARTAN": 5.281758681616276, "TIKOSYN": 14.197114362627648, "TOZINAMERAN": 1.1370566444145165, "TRACLEER": 0.3663780176131045, "TRELEGY": 0.4635390169511018, "TRULICITY": 0.7759730142472339, "VALSARTAN": 7.104071597069544, "VAXZEVRIA": 0.3010085688634738, "VFEND": 0.5270048812137293, "VIAGRA": 1.6082996327086032, "VIMPAT": 0.8167046951158973, "VOTRIENT": 0.733829455848819, "XALKORI": 3.912367495704781, "XARELTO": 1.2122200835529051, "XELJANZ": 0.5430801088865302, "XOLAIR": 1.5148030915810298, "XTANDI": 0.5945544925008102, "XYREM": 2.018743809974245, "ZYPREXA": 0.5511363874083463, "null": 1.9616947576709511}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5444.json
index ee717d9eeeb..c5aeccc6b53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5444.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5444.json
@@ -1 +1 @@
-{"MYCOPHENOLATE": 295.84022379430326}
\ No newline at end of file
+{"ABACAVIR": 0.0594391541495287, "ABILIFY": 0.4847318083836556, "ACTOS": 0.5705570245155812, "ADCIRCA": 1.4447247211604015, "ADEMPAS": 1.3957717437550352, "AERIUS": 1.011278162370044, "AFINITOR": 0.3651823194285415, "AGALSIDASE": 9.13627834487562, "AIMOVIG": 0.9747235712924788, "ALEMTUZUMAB": 0.6406746367841644, "ALIMTA": 0.1372767387559954, "AMBRISENTAN": 0.8273837875350118, "AMIKACIN": 0.3623713362019972, "AMINOSALICYLIC": 0.1412262517894028, "ANORO": 0.8865107745496149, "APIDRA": 0.3346832392341224, "APIXABAN": 3.223246548292053, "APROVEL": 1.3529192663305738, "ARANESP": 0.1022815382696303, "ARAVA": 0.0908140837172079, "ARIPIPRAZOLE": 0.9513955174454102, "ASPARAGINASE": 0.1936088415242018, "ATRIPLA": 0.0209307061910385, "AUBAGIO": 0.4472558415782352, "AVAMYS": 0.2299887498460071, "AVANDAMET": 0.8887615533165758, "AVANDIA": 0.4711920382661065, "AVASTIN": 0.3960089430353206, "BELIMUMAB": 1.1290789117598683, "BENLYSTA": 0.6118564874864071, "BENRALIZUMAB": 0.8215507792340964, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5445.json
index eeb20613977..201f5aedbed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5445.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5445.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 121.30209803279804, "CICLOSPORIN": 16.892041736139973}
\ No newline at end of file
+{"ABILIFY": 0.6992038076236279, "AERIUS": 1.8409001839819104, "AFINITOR": 0.2807543419023627, "AIMOVIG": 0.364849647817195, "APIXABAN": 0.5622282076721997, "ARAVA": 0.0422010188960275, "AUBAGIO": 0.3893457274998627, "AVANDAMET": 5.271241572513962, "AVANDIA": 6.273238005579436, "BETMIGA": 3.0533519580028323, "BUDESONIDE": 0.2578414212901746, "BYDUREON": 0.7130172640561582, "CHAMPIX": 0.7402899005887169, "CLOPIDOGREL": 1.1975863818268266, "COMIRNATY": 1.2833217553447391, "CYMBALTA": 0.3279910528931228, "ELIQUIS": 1.664397966728234, "ENBREL": 0.3855827186994783, "ENTRESTO": 3.0873467514235187, "ESBRIET": 1.7538265490726102, "ESOMEPRAZOLE": 1.3363385313422151, "EXFORGE": 2.249159403687182, "EXJADE": 0.687960524553496, "FORSTEO": 2.703183201535672, "FYCOMPA": 3.795845124338, "GARDASIL": 1.127679622073214, "HUMALOG": 0.5983372013577842, "IBUPROFEN": 0.4866809902476024, "INFLIXIMAB": 2.335261497722776, "INSULIN": 0.5715285058423963, "JANUVIA": 0.7745549010913858, "JARDIANCE": 0.2085386692692812, "KEPPRA": 0.2710732103068367, "LANTUS": 0.3379199928538084, "LATUDA": 1.1223991734392065, "LEMTRADA": 2.8213180159611917, "LEVEMIR": 0.9769697312432334, "LEVOFLOXACIN": 0.3233788868629854, "LYRICA": 0.7058863218673205, "MEPOLIZUMAB": 1.661656735858832, "METHOTREXATE": 0.6746129542353388, "MICARDIS": 0.7950107013452049, "MULTAQ": 6.985750944358415, "NUCALA": 0.4235245382555329, "OLANZAPINE": 0.4107092561310517, "OMALIZUMAB": 0.4571824556689289, "OPSUMIT": 0.9262924928827204, "PANTOPRAZOLE": 1.1997714964385506, "PEGASYS": 0.3812417495233697, "PEGINTRON": 0.2729088345830858, "PLAVIX": 0.3717105343172805, "PREGABALIN": 0.9816975157073412, "RITUXIMAB": 1.9529137358522768, "SOLIRIS": 0.4042421007233382, "SPIKEVAX": 1.3521881261248463, "SPRYCEL": 0.9552603119931832, "SUBOXONE": 0.5858072986749759, "SUTENT": 0.3182889520103928, "TASIGNA": 0.5835539904711954, "TOVIAZ": 1.2168158400499829, "TOZINAMERAN": 2.4796071332683014, "TRELEGY": 1.2194128928666188, "VAXZEVRIA": 0.7572769915340186, "VIAGRA": 1.5684696600990793, "VOTRIENT": 0.534993123005164, "XELJANZ": 0.7259191961918463, "XOLAIR": 1.6477811992584128, "XTANDI": 0.7846328307883377, "ZOSTAVAX": 0.7893601011934183, "ZYPREXA": 0.2927024691108739, "null": 1.217938709844448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5446.json
index 5eaee365b32..0685b8cf5e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5446.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5446.json
@@ -1 +1 @@
-{"ABACAVIR": 28.265747711225867, "ACLIDINIUM": 272.05132804874165, "AMINOSALICYLIC": 46.7131363565164}
\ No newline at end of file
+{"COMIRNATY": 2.6102113942271328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5447.json
index 7b50e20c96e..99cf62decc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5447.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5447.json
@@ -1 +1 @@
-{"ARAVA": 4.447792284993893, "CIMZIA": 13.202259101927009, "COSENTYX": 9.647511425556411, "LEFLUNOMIDE": 74.57893324652491, "SIMPONI": 17.61127486185552, "STELARA": 54.70661375516564, "TREMFYA": 43.98230610947639, "XELJANZ": 4.208125136182243}
\ No newline at end of file
+{"COMIRNATY": 5.20172707626531}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5448.json
index cffbcebb77d..5ca60856397 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5448.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5448.json
@@ -1 +1 @@
-{"null": 18.312818235900263}
\ No newline at end of file
+{"INSULIN": 508.8804626505858, "MEPOLIZUMAB": 94.94397371702748, "NUCALA": 38.85933927237095, "VAXZEVRIA": 0.4492836804310309}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5449.json
index f4f22529f98..31dae7615fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5449.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5449.json
@@ -1 +1 @@
-{"BIKTARVY": 1155.9796967217178}
\ No newline at end of file
+{"AVANDIA": 5.662628944136256, "CLOPIDOGREL": 6.192803808717119, "COMIRNATY": 0.1885902496739725, "SPIKEVAX": 0.2521978512069854, "null": 2.271323845388942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/545.json
index a316db39c8f..90174539f0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/545.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/545.json
@@ -1 +1 @@
-{"AVANDIA": 2.5261139334429763, "CICLOSPORIN": 1.1610057343154878, "CLOPIDOGREL": 2.3641183508725288, "ELIQUIS": 4.073779921137691, "ESBRIET": 6.36972424897701, "EXFORGE": 6.873072114304232, "FORSTEO": 3.8968635724481535, "IRBESARTAN": 7.628220743712314, "JANUMET": 4.494329680254895, "JANUVIA": 6.340050655965332, "OMALIZUMAB": 5.654030358498327, "PLAVIX": 4.924655058951651, "ROACTEMRA": 2.4132038316319524, "STELARA": 1.9897721529543448, "TASIGNA": 2.6651883678180024, "TESTOSTERONE": 18.258745645855708, "VIAGRA": 3.35385269780366, "XELJANZ": 2.023304278173464, "ZOSTAVAX": 5.545350830174395, "null": 1.5231279058248588}
\ No newline at end of file
+{"BORTEZOMIB": 25.58679349938668, "COMIRNATY": 0.1491727083444156, "DEXAMETHASONE": 7.687354726152503, "ELIQUIS": 3.8719464356423754, "ENTRESTO": 7.154680796279707, "INSULIN": 15.64404638596218, "LANTUS": 4.11899299092068, "null": 0.7994845499292648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5450.json
index 7e7f4e086bd..161165695a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5450.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5450.json
@@ -1 +1 @@
-{"GARDASIL": 16.890791795422807, "TIVICAY": 155.73506054310172}
\ No newline at end of file
+{"LANTUS": 5.982948142146345, "OPSUMIT": 15.580110357731838, "RAPAMUNE": 108.9795613801014, "TRACLEER": 44.40121679275831, "null": 0.8906956247624578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5451.json
index a60fe2dba62..232a3425e74 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5451.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5451.json
@@ -1 +1 @@
-{"ABILIFY": 4.907725424495013, "ANORO": 1029.534557542628, "APIXABAN": 146.55802373300943, "AZATHIOPRINE": 40.50645639063959, "COSENTYX": 6.427548504386733}
\ No newline at end of file
+{"AZATHIOPRINE": 29.67545756171909, "CELLCEPT": 23.14180941618654, "CICLOSPORIN": 111.9539682704614, "MYCOPHENOLATE": 378.3491857867693, "RAPAMUNE": 73.22073397811435, "null": 0.3363102005315294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5452.json
index f3fccd19c84..36ba7f89fe0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5452.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5452.json
@@ -1 +1 @@
-{"ABILIFY": 2.359942946443465, "ARIPIPRAZOLE": 1.547710975820272, "BRINTELLIX": 3.3979059289520803, "BUPRENORPHINE": 2.404934533720903, "CYMBALTA": 6.213169903612969, "DULOXETINE": 6.1913511874763145, "ENTACAPONE": 10.946730025066095, "FENTANYL": 6.625640480151256, "GARDASIL": 1.8453807463629053, "IBUPROFEN": 2.57348349358205, "KALETRA": 1.7019514901706445, "KEPPRA": 1.2836037054124625, "LYRICA": 2.413459283160653, "MELATONIN": 4.538616905507444, "MIDAZOLAM": 5.782620041476337, "NALOXONE": 14.660874080202383, "OLANZAPINE": 2.9582860582218924, "PREGABALIN": 9.183884803163398, "QARZIBA": 35.60914388603176, "VALDOXAN": 20.69534154483875, "ZYPREXA": 1.6630736245613005, "null": 5.07843861761456}
\ No newline at end of file
+{"null": 1.9499670788388528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5453.json
index b2d24c437f0..98611e7d764 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5453.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5453.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1350049026628084, "SPIKEVAX": 2.5794529249278506, "VAXZEVRIA": 3.867124625981779}
\ No newline at end of file
+{"AVANDIA": 7.480437648802755, "CIMZIA": 1.8131652922741368, "COMIRNATY": 0.2194899357928878, "ELIQUIS": 4.296079884373612, "ESBRIET": 8.610737610937539, "IBUPROFEN": 7.822223871148866, "SPIKEVAX": 0.2629428237715714, "TOZINAMERAN": 0.5808732772436552, "null": 1.6472980002754485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5454.json
index d81c64fe40b..0439064e430 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5454.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5454.json
@@ -1 +1 @@
-{"CELLCEPT": 3.2271846411120104, "COMIRNATY": 3.0083303713832867, "GARDASIL": 5.051379494696148, "KEYTRUDA": 1.5917870511123489, "SHINGRIX": 1.8162715233139255, "SIMPONI": 2.9197213969571445, "TELMISARTAN": 29.142288020288525, "TWINRIX": 16.771831940483228, "VAXZEVRIA": 1.7645260679437265}
\ No newline at end of file
+{"JARDIANCE": 20.00244847236067, "null": 0.6875127170729862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5455.json
index 189805587e4..d4ad45463a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5455.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5455.json
@@ -1 +1 @@
-{"BUSULFAN": 4.226140079003772, "CELLCEPT": 3.3311080675610008, "COMIRNATY": 1.1215611270777543, "COVID19": 2.0446528978229708, "GARDASIL": 10.712938448215867, "SHINGRIX": 3.615304624341296, "SPIKEVAX": 1.0339304491444647, "TOZINAMERAN": 4.412448005852357, "TWINRIX": 11.48003730302966, "VAXZEVRIA": 2.4969514427769828, "ZOSTAVAX": 5.733914332188312}
\ No newline at end of file
+{"AVANDIA": 8.088474615620378, "ELIQUIS": 7.878887067588237, "LANTUS": 8.501225370967846, "SIMPONI": 9.255261727526465, "TRELEGY": 14.04038006104879, "null": 1.0168270289872026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5456.json
index 32b43aef645..88f2b0368d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5456.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5456.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 1.7210331235575844, "ALIMTA": 1.0619774653329954, "ARANESP": 11.957347995660667, "AVASTIN": 1.230349165629487, "AXICABTAGENE": 21.785252719774228, "AZACITIDINE": 20.665504242509662, "AZATHIOPRINE": 1.3436050038912228, "BEVACIZUMAB": 2.63914603567144, "BORTEZOMIB": 10.459418173903924, "BRUKINSA": 19.880619736329056, "BUSULFAN": 7.161471491029698, "CAELYX": 6.218518014670228, "CAPECITABINE": 4.524067430787326, "CARFILZOMIB": 5.280110016837126, "CARMUSTINE": 81.4027984094622, "CELLCEPT": 1.3451779495763596, "CHLORMETHINE": 134.23063423773536, "CICLOSPORIN": 4.769597012916603, "CLADRIBINE": 62.9200925648239, "CYTARABINE": 16.599059698990477, "DECITABINE": 36.72531265495387, "DEXAMETHASONE": 6.3629723083324405, "DOCETAXEL": 4.9583661044732095, "DOXORUBICIN": 8.745734145159718, "EPOETIN": 12.66255227373563, "EVEROLIMUS": 4.7348508055082, "EXJADE": 33.35937060389989, "FILGRASTIM": 13.501437347217127, "IRINOTECAN": 4.005118359848836, "JAKAVI": 2.025101666666671, "KYMRIAH": 5.44973197528824, "LENALIDOMIDE": 13.058060614436116, "LUTATHERA": 18.3515893862464, "LUTETIUM": 114.05385490438854, "LYNPARZA": 66.9554390594016, "MABTHERA": 5.493830037244657, "MELPHALAN": 18.383451752961964, "MERCAPTOPURINE": 4.931076439286908, "METHOTREXATE": 2.3726271827000898, "MIRCERA": 12.569013326754238, "NEULASTA": 2.5998930586428264, "NOXAFIL": 11.827850148551256, "NPLATE": 45.83262020298119, "OLAPARIB": 84.84470807194162, "PLAVIX": 1.008254971191804, "RADIOTHERAPY": 76.19645250821675, "REVLIMID": 18.40211469710746, "RITUXIMAB": 7.532113316446473, "ROACTEMRA": 1.134152981930346, "RUBRACA": 8.928459387780606, "SOLIRIS": 9.82888400172119, "TASIGNA": 2.2255842714048435, "TEMODAL": 6.272516643396435, "TEMOZOLOMIDE": 32.27090725212073, "THALIDOMIDE": 6.728775349883188, "THIOTEPA": 13.236047168380043, "VENETOCLAX": 9.761312109831897, "VFEND": 4.260659062728707, "YESCARTA": 5.69639157441125, "ZEVALIN": 139.32337300908432}
\ No newline at end of file
+{"null": 1.3872398812792184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5457.json
index 364e7b6de4c..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5457.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5457.json
@@ -1 +1 @@
-{"EXJADE": 477.023938774888}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5458.json
index 111a957a42f..81361c00410 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5458.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5458.json
@@ -1 +1 @@
-{"CARMUSTINE": 187.05989123202315}
\ No newline at end of file
+{"COMIRNATY": 0.2032167110739307, "null": 1.1752605608746192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5459.json
index 15d0f9a9174..6272e3633f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5459.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5459.json
@@ -1 +1 @@
-{"ARANESP": 75.17752483159329, "CELLCEPT": 13.780979705435357, "MIRCERA": 77.4415955149014, "RITUXIMAB": 21.14767341963071}
\ No newline at end of file
+{"COMIRNATY": 0.6418833454933549, "FORXIGA": 22.23676104522316, "null": 0.6861799382854807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/546.json
index cfb26bc642b..6742c1def11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/546.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/546.json
@@ -1 +1 @@
-{"null": 1.7115280359095626}
\ No newline at end of file
+{"COMIRNATY": 1.173146576740555, "COSENTYX": 2.4919692264470825, "ENBREL": 3.62471799970405, "GARDASIL": 2.941585496084374, "RILUTEK": 287.1360725659436, "SIMPONI": 2.791571518521819, "SPIKEVAX": 0.9176226794239672, "TOZINAMERAN": 0.6161964814774269, "VAXZEVRIA": 0.1553999581620675, "null": 1.07349385123137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5460.json
index b2eb03ba967..7256d0251c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5460.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5460.json
@@ -1 +1 @@
-{"ANAGRELIDE": 245.4323693937629, "ARANESP": 2.8832966867905294, "BUSULFAN": 6.329638474031602, "EXJADE": 18.718076744532823, "JAKAVI": 325.718443353204, "NPLATE": 172.97106796132394, "RUXOLITINIB": 150.31914257748258}
\ No newline at end of file
+{"COMIRNATY": 0.4247173273690505, "OLANZAPINE": 11.723972374523012, "SPIKEVAX": 0.3356751061010384, "VAXZEVRIA": 0.4472708752329062, "null": 1.906993080532694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5461.json
index b00e796b97b..fbf49f8aae7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5461.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5461.json
@@ -1 +1 @@
-{"CICLOSPORIN": 9.022980588351649, "DASATINIB": 138.31933612043383, "null": 1.4370180597354345}
\ No newline at end of file
+{"null": 1.102950366923506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5462.json
index e2998e36555..e996712ede2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5462.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5462.json
@@ -1 +1 @@
-{"null": 1.609848241428752}
\ No newline at end of file
+{"AIMOVIG": 0.2268561393443464, "ALISKIREN": 0.6381626612875861, "APIXABAN": 0.06432424009765, "ARAVA": 0.0123237468967289, "AUBAGIO": 0.5267397441106674, "BENLYSTA": 0.1083915214592643, "BRILIQUE": 0.168295106882642, "BRINTELLIX": 0.2419873574879322, "CHAMPIX": 0.2351299873358808, "CIMZIA": 0.0639924524974651, "CLOPIDOGREL": 0.0681022923177977, "COMIRNATY": 10.04967375634502, "COSENTYX": 0.0500198230224432, "CYMBALTA": 0.0240465943930874, "CYTARABINE": 0.1746393735675612, "ELIQUIS": 0.3187670813161827, "ELLAONE": 4.733054172327333, "ENOXAPARIN": 0.1695690331431192, "ESMYA": 3.937071567551048, "EVRA": 1.843482278554036, "FAMPYRA": 0.181313266821581, "GARDASIL": 0.4502717040556414, "HYDROCORTISONE": 0.7733654182590878, "IBUPROFEN": 0.0723428016889564, "KAFTRIO": 0.3327208735231848, "KEPPRA": 0.0513458692693509, "LEMTRADA": 0.4188063659142565, "LIXIANA": 0.8521222299312117, "MACITENTAN": 1.4575562831818785, "MAVENCLAD": 0.5675995558949297, "MODERNA": 4.4604050797082975, "NPLATE": 0.2756849146935531, "OCRELIZUMAB": 2.643238479242716, "OPSUMIT": 0.0645152612118874, "ORKAMBI": 0.3586475943519888, "PEGASYS": 0.1705306886631809, "PEGINTRON": 0.0405627795480783, "PLAVIX": 0.067425551502487, "RINVOQ": 0.1432756800686092, "RYEQO": 18.50896560490084, "SAXENDA": 0.361143020434016, "SIMPONI": 0.0363586203770377, "SOLIRIS": 0.2343650787820995, "SPIKEVAX": 2.4727271822255936, "STELARA": 0.8092242919592878, "SUTENT": 0.0512491064221133, "TOZINAMERAN": 4.185421024327055, "TRACLEER": 0.0860232665068025, "VAXZEVRIA": 0.9579810223553128, "XARELTO": 0.8990698682984276, "XELJANZ": 0.0291811913355178, "XOLAIR": 0.0783360869500465, "ZYPREXA": 0.0564906629007458, "null": 0.0836481674421357}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5463.json
index 9b5f7a683cb..7c23dd83c26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5463.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5463.json
@@ -1 +1 @@
-{"ASPARAGINASE": 12.887382671684607, "BUPRENORPHINE": 6.326400490750471, "CYTARABINE": 15.337413912491414, "NAGLAZYME": 35.243267916551126, "ZOSTAVAX": 7.274613438673619}
\ No newline at end of file
+{"null": 1.1580364355015798}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5464.json
index 899c9abc0eb..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5464.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5464.json
@@ -1 +1 @@
-{"JAKAVI": 38.99379197621237, "NPLATE": 33.1015936978901, "null": 1.086471098086573}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5465.json
index 2a7c04dbd66..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5465.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5465.json
@@ -1 +1 @@
-{"ABEMACICLIB": 20.66017116223991, "ABRAXANE": 5.778864293248316, "ADCETRIS": 5.235131906938769, "ALIMTA": 8.335613859382482, "AMIKACIN": 1.3602530956795982, "ASPARAGINASE": 3.414780689926144, "ATEZOLIZUMAB": 1.1633679480971058, "AVASTIN": 9.426161035139668, "AXICABTAGENE": 4.29364959033556, "AZACITIDINE": 28.384324838937022, "BEVACIZUMAB": 18.740888338968787, "BLINCYTO": 4.683653799613817, "BORTEZOMIB": 5.9212924305736, "BRENTUXIMAB": 15.995376106483372, "BRUKINSA": 22.305217271544183, "BUSULFAN": 3.445198919691956, "CAELYX": 1.4458311507280508, "CAPECITABINE": 28.43857497139052, "CARFILZOMIB": 5.193264158219974, "CARMUSTINE": 3.967085255369893, "CELLCEPT": 1.685871617095973, "CETUXIMAB": 13.933715967767142, "CIDOFOVIR": 4.7153669730625785, "CLADRIBINE": 6.658471251034292, "CLOFARABINE": 1.9044256059756588, "COMBIVIR": 1.1941471775708676, "CYTARABINE": 20.35230207004287, "DARATUMUMAB": 2.0854331433781645, "DARZALEX": 5.293475992428948, "DASATINIB": 1.690029003472853, "DECITABINE": 32.22196203941578, "DEXAMETHASONE": 4.441662516911432, "DEXRAZOXANE": 179.84077526992706, "DOCETAXEL": 48.89011241487291, "DOXORUBICIN": 44.27675282111058, "EMEND": 1.582229864778555, "EPIRUBICIN": 123.38111695133507, "ERBITUX": 20.93513213507013, "ERIBULIN": 19.91577679508041, "FASLODEX": 1.5186960264201943, "FILGRASTIM": 1.6123345565761529, "FULVESTRANT": 2.101981274351814, "GANCICLOVIR": 8.681818500258082, "GAVRETO": 4.963177993943318, "GEFITINIB": 2.814276526251704, "GLIVEC": 1.3843817837361156, "HALAVEN": 30.660202447203687, "HERCEPTIN": 18.18597533459476, "HYCAMTIN": 5.49694849873427, "IBRANCE": 1.7261710506094656, "ICLUSIG": 1.8419750984264531, "IMATINIB": 2.4957919360987244, "IRINOTECAN": 8.368814537554545, "JEVTANA": 5.919793816580693, "KEYTRUDA": 2.060662072085421, "KYPROLIS": 3.31188692151381, "LENALIDOMIDE": 10.146210653105106, "LENVIMA": 1.5197300213565148, "LONSURF": 1.375655222856954, "LUTATHERA": 1.134477681885508, "LYNPARZA": 4.744439594719571, "MABTHERA": 48.20506914867611, "MANNITOL": 22.981492639911885, "MERCAPTOPURINE": 32.64145417093603, "METHOTREXATE": 5.883447214392253, "NILOTINIB": 1.4805584165749446, "NIVOLUMAB": 2.816398540645348, "NOT": 1.1403397240683777, "OBINUTUZUMAB": 9.993352816734342, "OLAPARIB": 10.070589398960326, "OSIMERTINIB": 3.9137885572720768, "PACLITAXEL": 42.57353739824841, "PALONOSETRON": 25.27011654010468, "PANITUMUMAB": 4.677550248368575, "PAZOPANIB": 1.250870329064071, "PEGASPARGASE": 92.99782563488202, "PEGASYS": 1.1745494932976814, "PEGFILGRASTIM": 2.175068292087747, "PEMBROLIZUMAB": 1.0270694001908838, "PEMETREXED": 44.96270929325553, "PERJETA": 10.975652294960303, "PERTUZUMAB": 21.30114627392455, "RITUXIMAB": 17.771099440325496, "SAVENE": 25.945340301620405, "SPRYCEL": 1.467567430245078, "STIVARGA": 1.748105441629059, "SUTENT": 1.1338541085756513, "TAGRISSO": 2.6984300502336844, "TASIGNA": 1.405338224126815, "TAXOTERE": 17.546431551703954, "TEGAFUR": 98.16820857735608, "TEMODAL": 8.264221843129564, "TEMOZOLOMIDE": 8.396614169605277, "THALIDOMIDE": 1.020294308238891, "THERAPEUTIC": 6.927597858062939, "THIOTEPA": 4.700370594290437, "TISLELIZUMAB": 150.64707793241547, "TOPOTECAN": 11.273516311575714, "TRASTUZUMAB": 23.164410871560133, "TRODELVY": 2.1499986772095654, "VECTIBIX": 2.773139160113045, "VENETOCLAX": 17.075808294633024, "VIDAZA": 6.565870778276999, "XELODA": 58.189299880052815, "XOFIGO": 6.721688788318357, "YONDELIS": 4.890360513337416, "ZEVALIN": 8.677926270546802, "null": 1.7718961197059315}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5466.json
index 79d92a4fc76..4954fc02fb2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5466.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5466.json
@@ -1 +1 @@
-{"null": 1.3193243928001126}
\ No newline at end of file
+{"RASBURICASE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5467.json
index f1be04a3d3a..f75688c427d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5467.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5467.json
@@ -1 +1 @@
-{"null": 1.3089659008738577}
\ No newline at end of file
+{"COMIRNATY": 0.0983749718503138, "null": 2.6835185421893595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5468.json
index 1a6c2c2e7ab..6e33b884f57 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5468.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5468.json
@@ -1 +1 @@
-{"null": 3.796835854988803}
\ No newline at end of file
+{"ABATACEPT": 18.71979509112216, "ACETAMINOPHEN": 67.5917558636739, "ADALIMUMAB": 32.68439532955782, "APREMILAST": 14.214965474978568, "APREPITANT": 82.99315107728042, "ARAVA": 31.054017827995203, "BIKTARVY": 2.1989374407539364, "BUMETANIDE": 3.866311578004487, "BYETTA": 0.7615885424002038, "CICLOSPORIN": 0.5488353694652267, "CIMZIA": 4.974396903837434, "COMIRNATY": 0.0167098292805449, "COSENTYX": 1.2295180785962228, "EFAVIRENZ": 2.4070585561439413, "ELIQUIS": 0.3518037190906319, "ENBREL": 0.5537581986077281, "ERELZI": 10.958209909794524, "FORSTEO": 0.3192643762302112, "GARDASIL": 0.5657828529613034, "HYDROCORTISONE": 1.1492591536770258, "INTRONA": 2.507787583909556, "JANUMET": 2.155500245708094, "JANUVIA": 0.8724564218210689, "METHOTREXATE": 0.5552808215377321, "MYCOPHENOLATE": 2.1221157607758925, "PEGASYS": 0.3426108762766596, "RITUXIMAB": 3.7466323239213386, "SPIKEVAX": 0.0131164001693589, "STELARA": 0.2192749602327459, "XELJANZ": 0.6286216212292561, "null": 0.2202976105859709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5469.json
index e2e63ab41f2..cd4d0a80bc4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5469.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5469.json
@@ -1 +1 @@
-{"OPTIMARK": 11.17510169807368, "SOMATROPIN": 99.93713553370924, "TESTOSTERONE": 92.16453514520332, "null": 1.3972083563916722}
\ No newline at end of file
+{"APIXABAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/547.json
index fa42c1548a8..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/547.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/547.json
@@ -1 +1 @@
-{"ELIQUIS": 3.889108045568736}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5470.json
index df7c55eaf87..d4b55304b4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5470.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5470.json
@@ -1 +1 @@
-{"null": 2.0495228807388}
\ No newline at end of file
+{"CLOPIDOGREL": 5.981060111650128, "ELIQUIS": 2.8758135483121414, "null": 2.2091296308076336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5471.json
index 72ac4eb9206..5b0a62da03a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5471.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5471.json
@@ -1 +1 @@
-{"OLANZAPINE": 254.2373242522463}
\ No newline at end of file
+{"null": 1.632028588574835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5472.json
index 79402a15550..f64eda4158a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5472.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5472.json
@@ -1 +1 @@
-{"ACTOS": 3.5967436696322275, "ALL": 1.0103782163845956, "ANAKINRA": 2.451164047016015, "ANGIOX": 4.128972686019072, "ANORO": 1.026931773483509, "APIDRA": 1.3460929894981426, "APIXABAN": 1.215428048401482, "APROVEL": 1.0740413243891538, "AVANDAMET": 63.61789877734254, "AVANDIA": 65.88708404164942, "AVASTIN": 1.1329372172561396, "BEDAQUILINE": 1.0768674123140274, "BETAFERON": 1.2600949114836648, "BOCEPREVIR": 1.037996790085192, "BOSULIF": 1.7695220355691663, "BOSUTINIB": 2.992635150452614, "BRILIQUE": 3.3876797851558, "BUDESONIDE": 1.011087085407712, "BYDUREON": 2.061323222620743, "BYETTA": 1.5372818664742334, "CHAMPIX": 1.5428137715091323, "CIALIS": 1.3719776716528114, "CLOPIDOGREL": 2.435864937934077, "COMBIVIR": 1.0316351471736265, "CRIXIVAN": 2.7842469452972254, "DAPAGLIFLOZIN": 2.613407920118109, "DELAMANID": 1.8210829546954748, "EFIENT": 1.354103970792476, "ELIQUIS": 1.8264568615043288, "ENTRESTO": 2.363289624422017, "ENZALUTAMIDE": 1.3089253552942843, "EPIVIR": 2.395919733274142, "ERENUMAB": 1.940473290540284, "ERLEADA": 1.4765339361965435, "ESBRIET": 1.6504405051729354, "EVENITY": 5.414172495557952, "EVISTA": 1.7638754416657163, "EVUSHELD": 1.9033940434163552, "EXFORGE": 1.657086842908092, "EYLEA": 2.8229705505699805, "FEBUXOSTAT": 5.898233011785821, "FORTOVASE": 3.742796175861603, "FORXIGA": 1.130186931459602, "GALAFOLD": 1.0723300436792402, "GALVUS": 1.5575476229748948, "GENVOYA": 1.1788643294039924, "HUMALOG": 3.3307101858068573, "ICLUSIG": 3.066776604543855, "INCRUSE": 1.6410064266788165, "INLYTA": 1.6702540268137929, "INSULIN": 1.538815820084037, "INTEGRILIN": 6.57120765111645, "INTELENCE": 2.15311431672718, "INVIRASE": 3.1964369748732766, "INVOKANA": 2.8731209675729468, "ISENTRESS": 1.5482811270472172, "JANUMET": 2.915181230998567, "JANUVIA": 1.966709934616422, "JARDIANCE": 3.609380148821226, "KIVEXA": 3.8757845799855386, "KYPROLIS": 2.52365714068476, "LANTUS": 2.813974321390978, "LENVIMA": 1.131892114555722, "LEVEMIR": 2.7526349727555184, "MEMANTINE": 1.2318782225499905, "MICARDIS": 2.2968766678505657, "MICARDISPLUS": 1.9083175298487525, "MIRCERA": 1.4524623029447965, "MIXTARD": 1.797985295253249, "NEXAVAR": 1.2486917047344328, "NILOTINIB": 2.908153651936296, "NORVIR": 1.576507284058333, "NOVOSEVEN": 5.689921343228859, "NPLATE": 1.2799854182875714, "OCRELIZUMAB": 1.0080602547021356, "OFEV": 2.170622258264545, "ONGLYZA": 6.590586636395497, "PLAVIX": 5.375368047075587, "PRASUGREL": 2.8012780644058526, "RANOLAZINE": 6.369605078928369, "RAPAMUNE": 1.5326630675829216, "REVATIO": 1.97455799136926, "RINVOQ": 1.5690375384176192, "ROACTEMRA": 1.0443410003858906, "ROSIGLITAZONE": 45.30991079890095, "SILDENAFIL": 1.5400293590112697, "SIMPONI": 1.027710325572962, "SKYRIZI": 1.8068044188105044, "SOVALDI": 1.1503085306016425, "SPRYCEL": 1.4842709485406826, "STELARA": 2.5867038276028844, "SYMTUZA": 1.7178159104733677, "TASIGNA": 4.50384630647375, "TEMSIROLIMUS": 4.519647519580414, "TERIPARATIDE": 1.2059726310213024, "TESTOSTERONE": 4.311761855990994, "TOUJEO": 1.8303165043837413, "TRACLEER": 1.0192593604773732, "TRELEGY": 3.237701485151042, "TREMFYA": 1.591574337216335, "TRIUMEQ": 4.083600852210179, "TRULICITY": 1.345807761506366, "VELTASSA": 2.7420414028758637, "VIAGRA": 5.754736676708825, "VICTOZA": 1.0224286699400484, "VOTRIENT": 1.254544240519241, "XARELTO": 1.3386604515440417, "XELJANZ": 1.3232296293399382, "XOLAIR": 1.1095180648124972, "XTANDI": 1.2708218152975992, "ZIAGEN": 1.2999276197544107, "ZYPREXA": 1.3098376515529386, "null": 1.2293127328334164}
\ No newline at end of file
+{"COMIRNATY": 0.5897599235402958, "SPIKEVAX": 0.524565111240252, "VAXZEVRIA": 0.9161931884534644, "null": 1.3101093027805215}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5473.json
index 2e7fd9ce9f5..ea45a01c7db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5473.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5473.json
@@ -1 +1 @@
-{"AVANDAMET": 147.73120757729404, "AVANDIA": 181.7509825862903, "KEYTRUDA": 1.392495786471418, "ROTATEQ": 11.973287805411006, "TOZINAMERAN": 2.3277096064839493}
\ No newline at end of file
+{"COMIRNATY": 6.662726369148217, "SPIKEVAX": 1.6690280926246115, "VAXZEVRIA": 0.5634802885458849, "null": 0.1638040869451594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5474.json
index 46a2866cc67..57d4d7f3983 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5474.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5474.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 2.2842172773270764, "AVANDAMET": 105.0980192728626, "AVANDIA": 75.73261401072858, "AVASTIN": 2.7856789725911706, "AZACITIDINE": 4.443949324395582, "AZATHIOPRINE": 1.261157230105133, "AZILECT": 14.943365240846106, "BEDAQUILINE": 5.316367139528253, "BRILIQUE": 2.2256297827583778, "CLOPIDOGREL": 2.6694494034922736, "DASATINIB": 33.602464866388445, "EMEND": 6.862248400903142, "ENTRESTO": 2.1172057876936594, "ENTYVIO": 1.1396869536441046, "ENVARSUS": 67.86487204535443, "FENTANYL": 3.346437421271826, "IBUPROFEN": 1.0893115718891957, "ICLUSIG": 6.990298694124772, "JAKAVI": 1.740069439362453, "KYPROLIS": 4.063369566035392, "LEVOFLOXACIN": 1.1599729603640707, "MICARDIS": 1.4308390159675115, "NEXAVAR": 2.83048811523868, "NILOTINIB": 14.560143763627284, "NOVOSEVEN": 6.970902287729764, "PLAVIX": 1.5444803483352347, "RITUXIMAB": 1.456817103478844, "ROSIGLITAZONE": 23.74918556953053, "STIVARGA": 1.5864065949032315, "TASIGNA": 8.118521790355238, "VOTRIENT": 1.058041976108219, "ZYPREXA": 1.0690472552001569}
\ No newline at end of file
+{"BORTEZOMIB": 25.0625688570322, "COMIRNATY": 0.8952619961211175, "ELIQUIS": 1.878359067463609, "SPIKEVAX": 0.2870204204867383, "VAXZEVRIA": 0.6701363542273711, "null": 0.9536521298695676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5475.json
index c42a8c3927e..6dcc7556e0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5475.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5475.json
@@ -1 +1 @@
-{"null": 1.210200739341985}
\ No newline at end of file
+{"null": 2.5880611525333377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5476.json
index bee166a9fc8..171d24859e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5476.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5476.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 6.676080168420926, "KEYTRUDA": 3.077639447265126, "SUTENT": 1.200421270498096, "null": 1.3350480100509567}
\ No newline at end of file
+{"COMIRNATY": 0.4303646601067227, "HUMAN": 28.925994433148357, "VAXZEVRIA": 0.2031724387170827, "null": 0.8589928940162272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5477.json
index 24fe544dff3..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5477.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5477.json
@@ -1 +1 @@
-{"ERENUMAB": 248.40339966835413, "SPIKEVAX": 1.51026518824306, "TOZINAMERAN": 2.7071847014629493}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5478.json
index f55fc9ee71a..db624e64dec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5478.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5478.json
@@ -1 +1 @@
-{"OLANZAPINE": 397.16674798978426}
\ No newline at end of file
+{"COMIRNATY": 1.9901060972330853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5479.json
index a8497103325..5a6cc0d34c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5479.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5479.json
@@ -1 +1 @@
-{"SILDENAFIL": 98.62741075263312, "null": 1.171086138891646}
\ No newline at end of file
+{"COMIRNATY": 7.668718921551703, "VAXZEVRIA": 1.6463538993223843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/548.json
index 103fc02e2bc..01444468374 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/548.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/548.json
@@ -1 +1 @@
-{"ADENURIC": 23.49110535832396, "ARANESP": 3.055648834068608, "AVANDIA": 5.367409323557069, "BYETTA": 14.444661576728985, "CLOPIDOGREL": 2.5021840563469584, "DELAMANID": 28.39991469915388, "ELIQUIS": 1.365541402526147, "EXFORGE": 5.060357905848247, "IBRANCE": 1.8444394914883997, "JANUMET": 29.015161014734176, "JANUVIA": 36.81995971072208, "KEYTRUDA": 2.50238390549157, "SUTENT": 1.3408555656008567, "TASIGNA": 11.145538448411177, "ZOMETA": 55.2295906269168, "ZOSTAVAX": 16.425604755919707}
\ No newline at end of file
+{"AVAMYS": 19.553073707509203, "COMIRNATY": 0.5099885397931033, "null": 0.8824432111601311}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5480.json
index 3403836b39e..7b0b6ec1c5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5480.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5480.json
@@ -1 +1 @@
-{"COVID19": 7.037313775342047, "SPIKEVAX": 1.1628633664834338}
\ No newline at end of file
+{"COMIRNATY": 4.727057248827813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5481.json
index 5863f391689..c6490dabd28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5481.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5481.json
@@ -1 +1 @@
-{"null": 10.792995139835782}
\ No newline at end of file
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5482.json
index 8085b262915..08ccedbd89e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5482.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5482.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 2.1106098592159195, "AVELUMAB": 6.266588365811183, "AXITINIB": 2.96007335532532, "BAVENCIO": 7.7464849406626, "BUSILVEX": 8.446375965893624, "COMIRNATY": 6.197062538509944, "DASATINIB": 1.904213315640024, "FYCOMPA": 1.244473084836656, "IPILIMUMAB": 8.622128064118565, "KEYTRUDA": 6.149165904754061, "LIBTAYO": 6.679995533611112, "LURASIDONE": 5.952689749045105, "NIVOLUMAB": 2.2610322161649843, "OLANZAPINE": 1.5947973174656684, "OPDIVO": 6.062662293770092, "PALIPERIDONE": 6.188728971692331, "PEMBROLIZUMAB": 5.851308603952155, "POTELIGEO": 7.022884251373756, "SPIKEVAX": 3.287676577148453, "TAMIFLU": 1.2946567826913036, "TOCILIZUMAB": 1.3259638625178929, "TOZINAMERAN": 4.348857025585666, "VALSARTAN": 1.146167137627587, "YERVOY": 1.0906946755866085}
\ No newline at end of file
+{"COMIRNATY": 8.120336782188133, "SPIKEVAX": 1.8121159927206376, "VAXZEVRIA": 0.7026546053734338, "null": 0.0956927472753451}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5483.json
index b12858db2d7..2c489fd4431 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5483.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5483.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 4.043547934673387, "BOTULINUM": 20.20744794153688, "BRIVARACETAM": 80.28682712562556, "GARDASIL": 2.0193118932054994, "KEPPRA": 39.77733889882512, "LACOSAMIDE": 35.509268693550474, "LEVETIRACETAM": 62.927670597876926, "LEVOFLOXACIN": 2.6898893096576564, "OLANZAPINE": 3.88617027874296, "VIMPAT": 17.582460393016248, "null": 1.501413695775205}
\ No newline at end of file
+{"COMIRNATY": 6.8288886632768175, "MODERNA": 4.068588214841811, "SPIKEVAX": 1.6469611531737085, "TOZINAMERAN": 1.100391230711663, "VAXZEVRIA": 1.632614730630624, "null": 0.0947737443640688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5484.json
index 423fde33933..85c389eb457 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5484.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5484.json
@@ -1 +1 @@
-{"ABILIFY": 1.2567560106260065, "ARIPIPRAZOLE": 2.771875190166911, "BOTULINUM": 2.5296490852367497, "BRIVARACETAM": 12.946037358036394, "BRIVIACT": 3.048821133390644, "BUPIVACAINE": 7.251053418117064, "CANCIDAS": 6.859555454295205, "CELECOXIB": 2.6012558103548904, "CELLCEPT": 1.2434358032662185, "CYMBALTA": 2.0798824258018125, "DEXAMETHASONE": 3.263760722752866, "DEXDOR": 34.91096421203645, "DEXMEDETOMIDINE": 11.69048483037068, "DULOXETINE": 5.931528322613611, "EBIXA": 10.89927844007874, "FENTANYL": 7.611023273666915, "GARDASIL": 1.5365222176957591, "GRANISETRON": 73.56009032098757, "HIZENTRA": 1.0392941825963655, "IBUPROFEN": 1.830968658593201, "INFANRIX": 2.5149029554247417, "KEPPRA": 5.136093523856046, "LACOSAMIDE": 6.623771508870318, "LEVETIRACETAM": 10.287496522898865, "LEVODOPA": 10.331335123572996, "LEVOFLOXACIN": 1.7904524500065824, "LOXAPINE": 32.00133395568836, "LYRICA": 6.473267967465594, "MEMANTINE": 13.408167635860384, "MIDAZOLAM": 7.981299992959979, "MMRVAXPRO": 1.7275078395256072, "NIMENRIX": 1.2529795027522237, "OLANZAPINE": 3.424352993200118, "PREGABALIN": 6.533716064282663, "REPAGLINIDE": 12.87899500681118, "RISPERIDONE": 10.635696612364184, "SODIUM": 24.15322610955697, "SUFENTANIL": 5.079150875332176, "TAMIFLU": 1.4149486140435672, "VIMPAT": 6.765741841462612, "ZYPADHERA": 1.6677470857022472, "ZYPREXA": 2.511097029462208, "null": 3.4533882796224136}
\ No newline at end of file
+{"ABACAVIR": 0.44612018531109, "AIMOVIG": 0.7584024872130091, "ALEMTUZUMAB": 2.201324466444449, "ALISKIREN": 73.54799271646382, "ARAVA": 0.0693197010505608, "ASPARAGINASE": 2.6633930267784547, "AUBAGIO": 4.841848999227047, "AVANDAMET": 3.016614290586319, "AVANDIA": 3.377832065202813, "AVASTIN": 0.8582600540666299, "BENLYSTA": 1.2934280246397003, "BETAFERON": 3.033009720895796, "BEVACIZUMAB": 3.5812492659425463, "BRILIQUE": 1.2066396289901755, "BRIVIACT": 4.707114367201571, "CELLCEPT": 0.5291808611130668, "CHAMPIX": 0.8779852451474857, "CICLOSPORIN": 1.6830968038236829, "CIDOFOVIR": 11.185868631595154, "CLOPIDOGREL": 3.981111146306435, "COMBIVIR": 1.658215253337997, "COMIRNATY": 1.3030852439195155, "CYMBALTA": 0.1893816278270582, "CYTARABINE": 1.404573348706297, "DEXAMETHASONE": 0.9835356405725628, "DOXORUBICIN": 1.0072075769475015, "EFAVIRENZ": 4.688211196906759, "ELIQUIS": 2.3349098281897582, "ENOXAPARIN": 5.045295980914968, "ENTRESTO": 0.3460481233603231, "ENTYVIO": 0.5525421386199806, "EVISTA": 1.3687051084166302, "EXFORGE": 0.6101473059262142, "EYLEA": 2.189341382191776, "FAMPYRA": 2.2582485908300614, "FENTANYL": 0.6040424803171033, "FORSTEO": 0.3507913812201526, "GARDASIL": 1.053108150735868, "GLIBENCLAMIDE": 4.794169196949426, "HIZENTRA": 0.8603102263469963, "HUMALOG": 0.7292777213434704, "INLYTA": 0.5990529898079315, "INSULIN": 0.4989800771631349, "IRBESARTAN": 2.7163461528893955, "JAKAVI": 1.2429232639150696, "KALETRA": 0.9048809868541882, "KEPPRA": 0.6975615936880477, "KESIMPTA": 4.337666077675605, "KEYTRUDA": 0.3812170319146986, "LACOSAMIDE": 1.3504687121680332, "LANTUS": 0.7460833900637167, "LEMTRADA": 3.021339659561258, "LEVETIRACETAM": 1.1054738218095863, "LIXIANA": 6.194982430785515, "MEKINIST": 0.8469191173899319, "METHOTREXATE": 0.3957136597890154, "MYCOPHENOLATE": 1.512277176706863, "NEXAVAR": 0.5111234696427077, "NOT": 1.9029346566598264, "NOVOSEVEN": 4.603973416240186, "PEGASYS": 0.2970752821200061, "PEGINTRON": 0.8221862410779175, "PLAVIX": 2.915492458851386, "RITUXIMAB": 0.5949689089277981, "RIVAROXABAN": 7.28423278734293, "SHINGRIX": 0.773796308964478, "SILDENAFIL": 1.330255294684478, "SIMPONI": 0.3026610346306714, "SOLIRIS": 0.6087728097891918, "SPIKEVAX": 0.7803571319711773, "STELARA": 0.4287868189001497, "SUBOXONE": 0.3976535261126491, "SUTENT": 0.5970041862197173, "TASIGNA": 1.9670390211052788, "TEMODAL": 4.2270607926352834, "TEMOZOLOMIDE": 7.633248053251657, "TOZINAMERAN": 0.9478462599917652, "TWINRIX": 1.663575664371997, "VAXZEVRIA": 0.7496880873166075, "VIAGRA": 1.959805474797535, "VOTRIENT": 0.6261857573268697, "XARELTO": 1.622124051303426, "XELJANZ": 0.1714112309201022, "XOLAIR": 0.7311724196491897, "XTANDI": 0.360152600340785, "YESCARTA": 1.3676973672841826, "ZOSTAVAX": 0.4209439544768654, "ZYPREXA": 0.7960264368244286, "null": 0.9232341464416416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5485.json
index bcfff6b53bb..193f2ac8812 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5485.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5485.json
@@ -1 +1 @@
-{"ABILIFY": 47.29777488164353, "ENBREL": 25.09936470855124, "GARDASIL": 6.330061632747766, "ZOSTAVAX": 8.38120436529354}
\ No newline at end of file
+{"ALISKIREN": 121.997391676684, "ARAVA": 0.0736539099734434, "AUBAGIO": 1.2669093077919429, "AVANDAMET": 2.893038001513855, "AVANDIA": 2.6499985934902237, "AVASTIN": 1.3962704218084772, "BETAFERON": 2.756704943379932, "BRILIQUE": 2.156875008570613, "BRIVIACT": 4.514095045470783, "CELECOXIB": 3.5062420895187807, "CHAMPIX": 0.4546764906974082, "CICLOSPORIN": 1.1859030430983106, "CLOPIDOGREL": 3.082796350094898, "COMIRNATY": 0.8411667190628532, "DEXAMETHASONE": 1.203026697581012, "EFIENT": 14.023861451095147, "ELIQUIS": 2.486888848365058, "ESOMEPRAZOLE": 15.04953935896331, "EVISTA": 2.445729005863231, "EXFORGE": 3.4331469953837863, "EYLEA": 6.701384233483764, "FENTANYL": 1.5799821271059975, "FORSTEO": 0.6268797836395695, "FORXIGA": 1.1512730905339272, "GARDASIL": 1.7586227465680506, "GLIBENCLAMIDE": 7.03976088340772, "HUMALOG": 1.5708133833631035, "INSULIN": 2.5989298683238418, "IRBESARTAN": 3.2293644339674965, "KEPPRA": 1.7327032481574272, "KEYTRUDA": 0.3896543697720246, "LANTUS": 1.9172119758518549, "LEVOFLOXACIN": 0.4984439554731151, "NEXAVAR": 1.3986534910423594, "PEGASYS": 0.4783745164832702, "PEGINTRON": 0.4257574291031216, "PLAVIX": 5.543115699598892, "SIMPONI": 0.4268633168672577, "SPIKEVAX": 0.5234701570163747, "STIVARGA": 0.8434945358561201, "SUFENTANIL": 4.1239994903891946, "SUTENT": 0.6038901194643638, "TASIGNA": 3.5207974447514374, "TEMODAL": 7.007870727675664, "TOZINAMERAN": 0.906282137504904, "VAXZEVRIA": 0.532259134451234, "VIAGRA": 2.741192564062448, "VOTRIENT": 0.843025093227983, "XARELTO": 6.492058862692474, "XOLAIR": 0.4940435485961134, "null": 1.0227989888431628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5486.json
index dcc70b891cc..2674967cd4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5486.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5486.json
@@ -1 +1 @@
-{"GARDASIL": 25.647032322582945, "null": 2.7354562412626264}
\ No newline at end of file
+{"COMIRNATY": 1.13453149622228, "FENTANYL": 14.844833303312027, "KAFTRIO": 50.69130162964955, "SPIKEVAX": 0.681911721406699, "TOZINAMERAN": 6.398572412270908, "VAXZEVRIA": 1.7613040557517592, "null": 0.3464110184280705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5487.json
index 9b549d57b2d..fcb334729c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5487.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5487.json
@@ -1 +1 @@
-{"CHOLESTAGEL": 993.1636323993032, "CICLOSPORIN": 2.556921231771057, "CUBICIN": 14.917097126754866, "NORVIR": 19.64221659720473, "OLANZAPINE": 2.2296958012160566, "RIVAROXABAN": 44.567448222234816, "ZYPREXA": 4.32845365190316, "null": 2.600188106237404}
\ No newline at end of file
+{"ISENTRESS": 480.30284527477977, "null": 1.4869856224624525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5488.json
index 90be3dcf122..7240fc81866 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5488.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5488.json
@@ -1 +1 @@
-{"null": 2.3165222645963905}
\ No newline at end of file
+{"COMIRNATY": 0.4814964866205223, "CUBICIN": 10.959818262048946, "GARDASIL": 6.845010088781863, "KEYTRUDA": 0.8765567991346731, "LEVOFLOXACIN": 2.193205997922832, "MMRVAXPRO": 4.151781861430987, "PLAVIX": 1.930890118242528, "SPIKEVAX": 0.4633308432551253, "STELARA": 2.4983459955511567, "TAMIFLU": 4.087286149918017, "TOZINAMERAN": 0.9814655062601494, "TWINRIX": 9.319312592505446, "VAXZEVRIA": 0.2795552313233063, "null": 2.243903858325803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5489.json
index 631f713775e..9bc2c6e415a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5489.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5489.json
@@ -1 +1 @@
-{"FENTANYL": 23.217841444389503, "null": 2.976063820706978}
\ No newline at end of file
+{"null": 1.481424803110106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/549.json
index 73aeb7b9ac3..fa9e11909eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/549.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/549.json
@@ -1 +1 @@
-{"ARAVA": 13.803300886070748}
\ No newline at end of file
+{"ABACAVIR": 0.5222068394911329, "ABASAGLAR": 0.1904828405018338, "ABATACEPT": 0.0294764539570303, "ABEMACICLIB": 2.4617573956389687, "ABILIFY": 0.1746913551628849, "ABRAXANE": 3.221139019553731, "ACLIDINIUM": 0.2543704285976015, "ACTOS": 0.9679478462937534, "ADALIMUMAB": 0.5277491193101621, "ADCETRIS": 2.023261524132719, "ADCIRCA": 1.7821991639673351, "ADEMPAS": 0.8644744113143475, "ADENURIC": 1.0475099727022508, "ADVAGRAF": 1.9066431136073976, "ADVATE": 0.4109207690705864, "AERIUS": 0.4451613297222751, "AFINITOR": 2.15690033855101, "AFLIBERCEPT": 1.2171615470161363, "AIMOVIG": 0.1183227993134818, "ALEMTUZUMAB": 0.664441118655042, "ALIGN": 7.573133338189613, "ALIMTA": 6.453276168811002, "ALISKIREN": 0.4923868917509369, "AMBRISENTAN": 1.5038472798826732, "AMIKACIN": 1.9904688957772696, "AMINOSALICYLIC": 7.750340702567592, "ANAGRELIDE": 4.594814524997642, "ANAKINRA": 0.0817027122238988, "ANIDULAFUNGIN": 2.371752324636192, "APIDRA": 0.1026514591244782, "APIXABAN": 0.43233606869102, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5490.json
index 6bfbcae3868..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5490.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5490.json
@@ -1 +1 @@
-{"null": 4.07007745522992}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5491.json
index 93cf5fb546a..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5491.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5491.json
@@ -1 +1 @@
-{"CICLOSPORIN": 9.311895683784783, "OLANZAPINE": 8.891634435323578, "null": 4.554983330015176}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5492.json
index 47c06ca5d0e..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5492.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5492.json
@@ -1 +1 @@
-{"COMIRNATY": 7.658790384145563, "SPIKEVAX": 1.1138425224083743}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5493.json
index 22514f5ccc8..c2fa46270e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5493.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5493.json
@@ -1 +1 @@
-{"null": 1.070559733320756}
\ No newline at end of file
+{"ARIXTRA": 17.00200692193224, "BIVALIRUDIN": 175.5513554064213, "CLOPIDOGREL": 1.4891223809570695, "COMIRNATY": 0.019146967301501, "ELIQUIS": 0.5064135400108507, "ENOXAPARIN": 124.06347169423198, "INHIXA": 33.89343939392273, "VAXZEVRIA": 0.124167473867366, "null": 10.174975609820368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5494.json
index fe979f42ebb..6f50cee46e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5494.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5494.json
@@ -1 +1 @@
-{"APIXABAN": 1.4390495698740962, "ASPARAGINASE": 3.482507513095783, "AZATHIOPRINE": 1.987662552792209, "BUDESONIDE": 1.0768175107160796, "CELLCEPT": 1.779261182336115, "CICLOSPORIN": 4.930714607294435, "COMBIVIR": 3.215027357134657, "CUBICIN": 14.004946015509192, "DEXAMETHASONE": 2.471734612230572, "IBUPROFEN": 1.092948232486021, "INSULIN": 1.5580573379592406, "IPILIMUMAB": 4.157478503697465, "ISENTRESS": 4.122208270356127, "KEYTRUDA": 1.6773150980315377, "LEVOFLOXACIN": 2.014961036992792, "MYCOPHENOLATE": 5.382053437002213, "OMALIZUMAB": 3.2253458972389915, "PEMBROLIZUMAB": 2.699496723212772, "STELARA": 1.3625013816380025, "TICAGRELOR": 4.604628449945429, "VFEND": 1.1610239680656314, "null": 3.3644495651859514}
\ No newline at end of file
+{"null": 9.287136915380955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5495.json
index d96e82dc9b8..25eb3f2e114 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5495.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5495.json
@@ -1 +1 @@
-{"CICLOSPORIN": 26.292027135629706, "null": 1.8137242369999087}
\ No newline at end of file
+{"VAXZEVRIA": 5.452241483132324, "null": 1.5882266254828457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5496.json
index 031a3e7015d..3e272157d46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5496.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5496.json
@@ -1 +1 @@
-{"COMIRNATY": 5.3983231716635975, "SPIKEVAX": 4.962108452054618, "TOZINAMERAN": 5.774145755946964}
\ No newline at end of file
+{"null": 1.0075421944574614}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5497.json
index a916c3c285d..4dde7ddf67e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5497.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5497.json
@@ -1 +1 @@
-{"CHAMPIX": 4.623903842525274, "GARDASIL": 1.3048509511189734, "HUMALOG": 3.4181106878652328, "LANTUS": 1.3529199699934886, "OZEMPIC": 84.64024074534038, "ZOSTAVAX": 4.930646479734463, "null": 4.2726863339301975}
\ No newline at end of file
+{"null": 2.520641570619253}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5498.json
index 9716f3b81ab..ab9942bdc32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5498.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5498.json
@@ -1 +1 @@
-{"COMIRNATY": 1.37031925988799, "OPTIMARK": 136.6886234996496}
\ No newline at end of file
+{"YESCARTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5499.json
index 82dcc7555ac..1c8f5664a70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5499.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5499.json
@@ -1 +1 @@
-{"ADCETRIS": 32.32992431704492, "ALIMTA": 2.1465364922288632, "AVELUMAB": 14.199936351905746, "AXITINIB": 9.919810495913202, "AZATHIOPRINE": 4.061141250784096, "BAVENCIO": 27.05833074633933, "BIKTARVY": 3.2123078701029257, "BRAFTOVI": 2.126588931767969, "BRILIQUE": 1.8944730272154249, "CABOMETYX": 1.5098476512107184, "CAPECITABINE": 2.662009030050384, "CICLOSPORIN": 1.4420382959682707, "COBIMETINIB": 14.818580655751855, "CUBICIN": 10.66438994533109, "FASLODEX": 1.6309592953364622, "GARDASIL": 1.455902958733266, "HUMAN": 3.288561023640566, "INLYTA": 1.247289863032048, "IPILIMUMAB": 23.00058399342101, "ISENTRESS": 8.930839917029676, "JAKAVI": 2.750650369892375, "KEYTRUDA": 20.54695776918828, "LIBTAYO": 24.899890572959738, "MEKINIST": 1.9254003985494303, "OPDIVO": 25.150991347116992, "PEGASYS": 1.672904993405118, "PEGINTRON": 1.1828425918078609, "PEMBROLIZUMAB": 17.149963639662726, "STELARA": 1.4552559038364732, "TAMIFLU": 1.9747228914021733, "TWINRIX": 4.152910507792303, "ZOSTAVAX": 1.2038224774421862}
\ No newline at end of file
+{"NOT": 316.24411147327004, "PEGINTRON": 65.52921356671662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/55.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/55.json
index 1ec57d88210..92d88b2dfa5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/55.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/55.json
@@ -1 +1 @@
-{"ASPARAGINASE": 430.01279390507}
\ No newline at end of file
+{"AIMOVIG": 1.3504307237817843, "AUBAGIO": 1.071834978687013, "CHAMPIX": 0.7041536595669756, "CICLOSPORIN": 0.6752042002773871, "CLOPIDOGREL": 0.6541259720758323, "COMIRNATY": 1.493076830893422, "CYMBALTA": 0.2559788239840655, "ELIQUIS": 0.590867402944462, "ENTYVIO": 5.5651680839521935, "EXJADE": 1.1763393345247803, "FORXIGA": 1.1558504084368764, "GARDASIL": 0.5692734259193787, "IBRANCE": 0.4195115200779986, "INFANRIX": 4.7365412803820215, "JARDIANCE": 0.8447557353730536, "LEVOFLOXACIN": 0.8902331716855825, "MMRVAXPRO": 2.2191072859617997, "OFEV": 1.6414364496536955, "PEGINTRON": 0.6714992636803642, "ROTATEQ": 19.91638527895577, "SAXENDA": 1.5005478510832848, "SPIKEVAX": 1.10456262895814, "STELARA": 0.4322627950392307, "SUTENT": 1.364716175983756, "TAMIFLU": 3.903878360679762, "TOZINAMERAN": 0.389447007306762, "VAXZEVRIA": 1.2861320154020048, "VOTRIENT": 1.0725417564789252, "XELJANZ": 2.392530819149343, "ZYPREXA": 0.4630680778451655, "null": 1.0320193945705882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/550.json
index fb970cc6e72..33ba0d6c31d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/550.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/550.json
@@ -1 +1 @@
-{"ZOSTAVAX": 6.494769559683469, "null": 1.0397906634490834}
\ No newline at end of file
+{"null": 1.0371637327994034}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5500.json
index fd99735e6e4..a174b164972 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5500.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5500.json
@@ -1 +1 @@
-{"null": 1.691040399517562}
\ No newline at end of file
+{"null": 0.2844358711963882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5501.json
index 20020f8a1a6..97367c0abf3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5501.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5501.json
@@ -1 +1 @@
-{"null": 1.115179498463266}
\ No newline at end of file
+{"AVASTIN": 42.48416653659967, "null": 2.6228591978770406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5502.json
index 2eaa598f27b..49e5951dfee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5502.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5502.json
@@ -1 +1 @@
-{"null": 1.53567740245871}
\ No newline at end of file
+{"null": 0.3466418178452108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5503.json
index 4b9b874b476..29d70f6a2c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5503.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5503.json
@@ -1 +1 @@
-{"SUTENT": 8.682577424173445, "null": 1.019236823012075}
\ No newline at end of file
+{"AVANDIA": 0.3875267826015034, "BARACLUDE": 46.23848180227015, "BYETTA": 2.947015358870562, "CABOMETYX": 3.131920151152616, "CICLOSPORIN": 0.3759358310656864, "COMIRNATY": 0.0134556080187888, "COSENTYX": 0.3235662893449499, "DACLATASVIR": 7.679390704427341, "DAKLINZA": 13.093020709827162, "DARUNAVIR": 9.518606446442176, "ELIQUIS": 1.0710585811900155, "ENTECAVIR": 8.954113847391804, "EPCLUSA": 7.215967324859996, "EXFORGE": 1.2993724861160203, "FASLODEX": 0.7996632916564541, "FORSTEO": 1.2590176122167296, "HARVONI": 14.97648138783986, "HEPSERA": 18.086266146471115, "HUMALOG": 0.532895868700222, "IBRANCE": 0.5939784614717222, "INSULIN": 0.7570938054785231, "JANUMET": 2.0890611598548445, "JANUVIA": 1.795122608747373, "JARDIANCE": 1.1138997589599238, "KALETRA": 4.897187297161806, "LANTUS": 1.7133099210074505, "LEVEMIR": 1.1898843541636377, "NEXAVAR": 26.53183321462419, "OLYSIO": 5.621424277234415, "PEGASYS": 2.730850008307717, "PEGINTERFERON": 2.6258783517408126, "PEGINTRON": 2.160604981712785, "REBETOL": 4.745768428083379, "RIBAVIRIN": 7.509593228685498, "SOVALDI": 14.629033122198743, "STELARA": 0.9519113237852052, "STIVARGA": 1.9323015404876656, "SUTENT": 0.3926161909163602, "TRACLEER": 0.766686082998788, "TRELEGY": 1.562136424040655, "VEMLIDY": 20.873704873934525, "VICTOZA": 1.2049108940776538, "VIREAD": 2.784639777042697, "VOTRIENT": 0.7158068935219524, "XELJANZ": 0.6196053115159759, "XTANDI": 0.4313194745689628, "null": 3.8020160317595577}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5504.json
index cdbe4abff4e..15607c02804 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5504.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5504.json
@@ -1 +1 @@
-{"IRBESARTAN": 400.94499438346753}
\ No newline at end of file
+{"BYETTA": 28.547028122901526, "COMIRNATY": 0.2611490080436846, "NEXAVAR": 22.59660865467791, "null": 0.7814857369626694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5505.json
index 701d9221faa..42be4aec216 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5505.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5505.json
@@ -1 +1 @@
-{"APIXABAN": 5.526574847574149, "CLOPIDOGREL": 14.236723301531814, "ELIQUIS": 3.2214260905396137, "ENALAPRIL": 148.79490798639085, "ENTRESTO": 100.90825695767376, "IVABRADINE": 80.44381262534556, "JARDIANCE": 2.4423761711162544, "KEYTRUDA": 1.879648208904276, "OPSUMIT": 7.347931725609952, "TRACLEER": 5.34967562309036, "VALSARTAN": 70.02456107608491}
\ No newline at end of file
+{"HARVONI": 229.73980363895225, "NEXAVAR": 23.004327011639884, "PEGASYS": 8.891482554877246, "SOVALDI": 602.0039890255414, "null": 0.097489775570382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5506.json
index 31f8e1e35a4..f8eea3a00f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5506.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5506.json
@@ -1 +1 @@
-{"AVAMYS": 2578.1190087691425}
\ No newline at end of file
+{"NEXAVAR": 21.91977100199012, "null": 1.6633378125826677}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5507.json
index 9c873571f0e..f3651c6cbd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5507.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5507.json
@@ -1 +1 @@
-{"null": 1.6406247505359015}
\ No newline at end of file
+{"ABACAVIR": 2.746889785944175, "ABATACEPT": 0.5291473424504721, "ABILIFY": 0.6811572855174668, "ACTOS": 4.166404044301671, "ADALIMUMAB": 2.6124044440159806, "ADCIRCA": 7.033824432351459, "AFINITOR": 0.5828518799796544, "AMINOSALICYLIC": 2.646538969577636, "APIDRA": 0.648439208998804, "ARANESP": 0.4294387845914056, "ARAVA": 1.8443759279420933, "ATAZANAVIR": 1.3910196211986905, "ATRIPLA": 0.2977928591907599, "AUBAGIO": 0.6036723740852014, "AVANDIA": 2.595557005903756, "AVASTIN": 1.0913775756178383, "AZATHIOPRINE": 0.9034392373107926, "BARACLUDE": 21.07978926239514, "BETAFERON": 1.7985341307157163, "BIKTARVY": 3.250563380271834, "BOCEPREVIR": 7.646238729680586, "BOTULINUM": 3.0926817373746704, "BUPRENORPHINE": 0.4946932819754157, "BYDUREON": 0.6671751708221091, "BYETTA": 3.053137954394757, "CAPECITABINE": 1.4816948834217347, "CELLCEPT": 0.6729140019483638, "CERTOLIZUMAB": 18.610653760146523, "CICLOSPORIN": 1.6248192820218668, "CIMZIA": 0.4176954337571607, "CLOPIDOGREL": 0.2462616017507754, "COAPROVEL": 1.644017803396611, "COMIRNATY": 0.0260409978972764, "COSENTYX": 1.841219825986239, "CRIXIVAN": 4.080061379530517, "CYMBALTA": 2.143769611106274, "DACLATASVIR": 17.979465592968364, "DAKLINZA": 15.425507515045556, "EFAVIRENZ": 2.6959362093716166, "ELIQUIS": 0.6690432863310495, "ENBREL": 0.3996840609479833, "ENTECAVIR": 17.91011149176656, "ENTRESTO": 0.4033986916278293, "ENTYVIO": 1.0371050082499405, "EPCLUSA": 29.92627406492871, "EPIVIR": 10.081449847375742, "EXJADE": 2.352722657010078, "EXVIERA": 34.06868530255819, "FASLODEX": 1.3028828766198377, "FENTANYL": 0.3122997564438287, "FORSTEO": 0.7750780217166068, "HALAVEN": 2.8865913712369187, "HARVONI": 17.77469453588154, "HEPSERA": 8.428477113072669, "HUMALOG": 1.9746035295001296, "HUMIRA": 1.0465160385343768, "IBRANCE": 0.8309049114441072, "INCIVO": 8.140975922628007, "INSULIN": 0.6508072220632957, "INTELENCE": 10.659739972018835, "INTERFERON": 8.66354073960194, "INTRONA": 7.215738714312078, "INVIRASE": 7.95494270063493, "ISENTRESS": 2.3439797942780887, "JAKAVI": 1.2733390657034127, "JANUMET": 4.981851977366819, "JANUVIA": 2.62291633798551, "JARDIANCE": 1.0755806469295193, "KAFTRIO": 3.771938892981274, "KALETRA": 1.80486837842458, "KEPPRA": 0.4224241636002818, "KEYTRUDA": 0.3240618684272211, "LAMIVUDINE": 2.423112709854484, "LANTUS": 1.4714483106691754, "LEVEMIR": 2.488783751751845, "METHOTREXATE": 2.4016999156743983, "MULTAQ": 1.4533071264308648, "MYCOPHENOLATE": 1.391505539886466, "NEXAVAR": 3.32044331466792, "NOVORAPID": 0.6252048354548987, "NPLATE": 5.375563519809614, "OBETICHOLIC": 52.45252841805807, "OCALIVA": 44.77995960243233, "OLANZAPINE": 0.3903074993713046, "OLYSIO": 12.51313699003402, "OPSUMIT": 2.2097995958867704, "PANTOPRAZOLE": 1.1022675240896085, "PEGASYS": 10.55538089373633, "PEGINTERFERON": 5.24890516232784, "PEGINTRON": 6.160783178397923, "REBETOL": 6.238490070092362, "REVATIO": 2.2934915622820333, "REYATAZ": 3.768678234504326, "RIBAVIRIN": 18.211423949475275, "ROACTEMRA": 0.6018885127100831, "SKYRIZI": 5.020717179041319, "SOLIRIS": 1.038015224882174, "SOMATROPIN": 26.67277078647569, "SOVALDI": 22.786745654044303, "SPIKEVAX": 0.0538793830743004, "STELARA": 2.226541402018878, "STIVARGA": 0.8484879229321548, "SUBOXONE": 1.8296656312050912, "SUTENT": 0.1275257258772515, "TASIGNA": 1.1536893917191458, "TOZINAMERAN": 0.0662614902204826, "TRACLEER": 3.263835706207077, "TREMFYA": 2.2136429894342617, "TRULICITY": 1.18830830170811, "TRUVADA": 0.1228792886444727, "VAXZEVRIA": 0.0274529761699882, "VFEND": 0.7483263624961068, "VIAGRA": 0.541813250601829, "VICTOZA": 2.08350821616508, "VIRAMUNE": 6.312214284861156, "VIREAD": 4.001487236745732, "XELJANZ": 0.7443465291576012, "ZEPATIER": 12.134097510682, "ZOSTAVAX": 0.747706633261984, "ZYPREXA": 0.9282800824750328, "null": 0.7153957720317495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5508.json
index e8ac75b5bf8..b42ec8a74e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5508.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5508.json
@@ -1 +1 @@
-{"ABRAXANE": 1241.19955539701}
\ No newline at end of file
+{"ADENURIC": 24.882408166713347, "ARAVA": 1.3195513936893797, "BYETTA": 10.055521341695576, "CARMUSTINE": 29.015323312332637, "CLOPIDOGREL": 2.237382995872468, "COMIRNATY": 0.1934558631434353, "CYMBALTA": 0.9897609800645186, "IBRANCE": 1.4323348295080414, "JANUMET": 17.33083394402624, "JANUVIA": 11.927521072229212, "KEYTRUDA": 1.851090478391442, "MEPOLIZUMAB": 7.419736213518512, "NEXAVAR": 2.2306814444562675, "PEGASYS": 1.976702336261432, "SPIKEVAX": 0.1872389246136189, "SUTENT": 1.2263136308747409, "ZOSTAVAX": 2.336020687458286, "null": 0.9465492668279992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5509.json
index 91cb0191ad5..23fd4a88e85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5509.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5509.json
@@ -1 +1 @@
-{"SUTENT": 4.857093848368591}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/551.json
index f42f25f21d9..64c372ded88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/551.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/551.json
@@ -1 +1 @@
-{"ELIQUIS": 9.679407215332107, "ZOSTAVAX": 10.55803426113151, "null": 1.4404860322677937}
\ No newline at end of file
+{"ARAVA": 0.3351148257537849, "CLOPIDOGREL": 2.3454963663843547, "COMBIVIR": 90.36771396112262, "COMIRNATY": 0.0528283335749883, "ELIQUIS": 2.253928599965841, "EPIVIR": 20.41601545663509, "ESOMEPRAZOLE": 10.611743755698138, "IBRANCE": 3.405188735784974, "KALETRA": 5.241635182301193, "PEGASYS": 4.5229869174040775, "PEGINTRON": 2.887803207817908, "PLAVIX": 1.7015821138862917, "SUTENT": 0.8906726106890152, "null": 1.163930715254231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5510.json
index 50c396a06d4..8fd08a0b7b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5510.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5510.json
@@ -1 +1 @@
-{"TAGRISSO": 116.04007033133642}
\ No newline at end of file
+{"ABACAVIR": 0.7399074872782359, "AMINOSALICYLIC": 1.7580159077347244, "ASPARAGINASE": 5.06722416348333, "ATRIPLA": 0.2105495774624898, "AVANDIA": 0.7123795663318997, "AZATHIOPRINE": 1.3597713276610857, "BARACLUDE": 14.602783825908674, "BOCEPREVIR": 11.507872578266722, "BUDESONIDE": 0.4419053081947457, "BUSULFAN": 1.696193657811358, "CABOMETYX": 6.08890780555587, "CAPECITABINE": 1.637804146978329, "CICLOSPORIN": 0.492346462643759, "COMIRNATY": 0.0083483416396404, "CYMBALTA": 0.570748273938417, "DACLATASVIR": 21.348871507731868, "DAKLINZA": 16.162011192807157, "EPCLUSA": 25.13926692887764, "EXJADE": 1.2321882635987178, "EXVIERA": 45.286269277756666, "FASLODEX": 1.0471769798191994, "FUZEON": 61.340033465269, "HARVONI": 20.57371811762984, "IBUPROFEN": 0.9445688711969414, "INCIVO": 3.016371032849432, "INTRONA": 5.475564904564629, "IRINOTECAN": 2.515806126686099, "JANUVIA": 0.712493235668095, "KEPPRA": 0.52627431362681, "KEYTRUDA": 0.6340302747683715, "LAMIVUDINE": 11.26171137728526, "LANTUS": 0.2305149563888799, "LENVIMA": 128.29548863085378, "LEVETIRACETAM": 1.7423673437331295, "MIDAZOLAM": 1.8130453975507863, "NEXAVAR": 42.154087398225926, "NPLATE": 1.831962684180476, "OCALIVA": 12.694429734823943, "OLYSIO": 20.83149632821512, "OPDIVO": 1.471165055236392, "OPSUMIT": 1.4427249750350355, "PANITUMUMAB": 23.76121476728033, "PEGASYS": 5.130926981523602, "PEGINTERFERON": 6.438705734719675, "PEGINTRON": 6.377218557353179, "REBETOL": 15.975200747232927, "RIBAVIRIN": 15.927670214224351, "RITUXIMAB": 1.309837638130413, "SAMSCA": 30.619023253576987, "SOMATROPIN": 44.40357586596575, "SORAFENIB": 10.293247755647284, "SOVALDI": 28.74600624895768, "STIVARGA": 16.78642664509995, "SUTENT": 0.1715525439698055, "VFEND": 1.4132162373100037, "ZYPREXA": 0.4583537776125364, "null": 0.9457066894827452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5511.json
index 0e75a9a7c0f..d568ea34dbf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5511.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5511.json
@@ -1 +1 @@
-{"null": 1.1027747526015266}
\ No newline at end of file
+{"ADALIMUMAB": 0.3020233447058427, "ARAVA": 0.3019027800663936, "AUBAGIO": 3.6050078570474144, "AZATHIOPRINE": 4.561149693825301, "CIMZIA": 0.7553976430460962, "CLOPIDOGREL": 3.4865343872054546, "COMIRNATY": 0.1334666466150421, "COSENTYX": 3.669342737376634, "CYMBALTA": 1.367095034857341, "ELIQUIS": 0.4831511478928328, "ENBREL": 3.4898519713409897, "EXJADE": 1.7482894985235709, "FASLODEX": 2.5006086668954843, "HUMIRA": 1.8881026896558075, "IBRANCE": 1.4125496698521782, "INLYTA": 3.9921451382715145, "JARDIANCE": 0.9661145723010416, "KEPPRA": 1.724062542624658, "KEYTRUDA": 1.0356313914364923, "MEKINIST": 2.605361486140992, "METHOTREXATE": 2.707259107679366, "OLANZAPINE": 2.0677164576301026, "OPSUMIT": 2.013531734060102, "PEGASYS": 0.7265855966650413, "SUTENT": 1.4856773040924391, "TOZINAMERAN": 0.2491625336735776, "TRACLEER": 3.5663816642106645, "VFEND": 3.046953638345157, "VOTRIENT": 2.2391631483056647, "XELJANZ": 1.415339818411152, "ZYPREXA": 2.7636323268437946, "null": 1.34204364744565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5512.json
index 6efcc131de8..a6ca2dc40a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5512.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5512.json
@@ -1 +1 @@
-{"ABACAVIR": 3.662884932648735, "COMBIVIR": 8.117974909087486, "FORSTEO": 2.4712843628663403, "IBRANCE": 3.305925556801524, "PEGASYS": 1.3697730194118816, "SUTENT": 5.7942836014471215}
\ No newline at end of file
+{"null": 0.4205167284081899}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5513.json
index 498d95cc0ac..122e4064e32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5513.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5513.json
@@ -1 +1 @@
-{"ABATACEPT": 32.04519269060555, "ADALIMUMAB": 2.028716930403175, "AFINITOR": 5.515484474578983, "AIMOVIG": 1.5696725269315104, "ARAVA": 2.6396625440550934, "AUBAGIO": 3.785382125654896, "CAPECITABINE": 5.124982319852399, "CIMZIA": 7.334374446264041, "COSENTYX": 3.4036219832946166, "DOCETAXEL": 14.73465580338538, "FORSTEO": 1.218574598804142, "HERCEPTIN": 11.556539537691254, "IBRANCE": 8.247312251240555, "IRESSA": 11.708200467416654, "KEPPRA": 1.933988911750366, "PEGASYS": 1.5151250016338718, "SUTENT": 2.415419447979621, "TAGRISSO": 27.50616212964865, "TORISEL": 17.982508451786252, "XELJANZ": 1.1224925013132498, "XTANDI": 1.25109331914848}
\ No newline at end of file
+{"ABACAVIR": 16.164598524776167, "ABATACEPT": 5.271144458121476, "ABILIFY": 0.3690509007407408, "ACETAMINOPHEN": 14.27090988199706, "ACLASTA": 2.8789150738840488, "ACLIDINIUM": 6.53294544579161, "ADALIMUMAB": 5.58946194037622, "ADENURIC": 1.2037753858139753, "AERIUS": 1.0502026079716056, "AFINITOR": 0.7656788813494931, "AGOMELATINE": 4.059472798678062, "AIMOVIG": 0.2151014259896168, "ALEMTUZUMAB": 0.2663979449229391, "ALIMTA": 0.2717758064255758, "ALOXI": 8.90267033169458, "AMIKACIN": 3.0312665364121374, "AMINOSALICYLIC": 1.4561652280761563, "AMPRENAVIR": 8.899852357985706, "ANAKINRA": 1.184316603142064, "ANORO": 0.5671100008682186, "ANTIBIOTICS": 1.6865415508001511, "APREMILAST": 6.670186334260973, "APREPITANT": 16.99299136086368, "APROVEL": 0.6094717548293515, "APTIVUS": 7.6700180362842625, "ARAVA": 8.841905785139128, "ARIPIPRAZOLE": 0.305322433441212, "ASPARAGINASE": 0.5064373618898431, "ATAZANAVIR": 0.5408662955212928, "ATRIPLA": 0.093075731139264, "AUBAGIO": 3.801195248528876, 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"XARELTO": 0.7661320235727044, "XELJANZ": 1.0770461173864896, "XELODA": 0.6504104616281984, "XOLAIR": 0.2409942504150825, "XTANDI": 0.3019596900883449, "YERVOY": 1.77496020560525, "YONDELIS": 3.4749654815084074, "ZELBORAF": 1.1063296781418606, "ZIAGEN": 1.5975330365072848, "ZOSTAVAX": 0.0803443218821653, "ZYPREXA": 2.8548741222927885, "null": 1.0818264649563392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5514.json
index 115c1aec750..0ae72411435 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5514.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5514.json
@@ -1 +1 @@
-{"CICLOSPORIN": 7.879142184593298}
\ No newline at end of file
+{"ABACAVIR": 0.2985000322157725, "ACTOS": 3.315944750371807, "AFINITOR": 1.6103724917914168, "ALEMTUZUMAB": 1.280024232448883, "ALIMTA": 1.245986316987159, "AMINOSALICYLIC": 1.281836193680547, "APIXABAN": 0.1859847247735991, "ARAVA": 0.3827046034794426, "ASPARAGINASE": 2.305920437185893, "ATAZANAVIR": 1.185771097436882, "ATRIPLA": 0.174774287660962, "AUBAGIO": 0.3486263809592945, "AVANDAMET": 1.7347803489390954, "AVANDIA": 3.236832711774552, "AVASTIN": 1.3417739191849354, "AZACITIDINE": 2.084752138218937, "AZATHIOPRINE": 0.830376118480391, "BARACLUDE": 8.603040182070085, "BEVACIZUMAB": 2.0119081364082563, "BIKTARVY": 1.252996202748378, "BOCEPREVIR": 5.513339956177235, "BORTEZOMIB": 0.9517470394013836, "BRAFTOVI": 1.060170714021598, "BUSULFAN": 3.61506945925111, "BYDUREON": 0.2788993003920718, "BYETTA": 0.5961125280595293, "CABOMETYX": 1.2062128506804866, "CANCIDAS": 7.318640578884482, "CAPECITABINE": 1.9089590200858773, "CASPOFUNGIN": 3.873910618107945, "CELLCEPT": 1.8067805415828908, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5515.json
index 4ff1d1d5be3..9035083e1c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5515.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5515.json
@@ -1 +1 @@
-{"ARAVA": 1.858871363672293}
\ No newline at end of file
+{"ADALIMUMAB": 0.5597539833305584, "ARAVA": 2.2515013056776083, "ARIPIPRAZOLE": 4.628705886676309, "AZATHIOPRINE": 7.55510415926069, "CICLOSPORIN": 12.06781370845746, "COMBIVIR": 8.088944048381823, "ENBREL": 10.103968838474696, "EXJADE": 4.473366987393571, "HUMIRA": 3.12431126169822, "METHOTREXATE": 3.1101457860032475, "OCALIVA": 79.48418554905066, "PEGASYS": 4.754606118452727, "PEGINTRON": 3.994828936692246, "RIBAVIRIN": 8.477722510818781, "SOVALDI": 12.041285487330828, "null": 0.8273878201958117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5516.json
index cb02c05dc78..98e3b059731 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5516.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5516.json
@@ -1 +1 @@
-{"XELJANZ": 9.919580006167063}
\ No newline at end of file
+{"ABACAVIR": 0.4246608920626351, "ABILIFY": 0.3272474015856207, "ABRAXANE": 0.7600723038089291, "ACTOS": 3.043681227231443, "ACTRAPID": 1.565891883625952, "ADALIMUMAB": 0.0201276994643121, "ADCETRIS": 1.900223480657396, "ADCIRCA": 1.5473313440807073, "ADEFOVIR": 3.9970933837906446, "ADEMPAS": 0.8442753952705654, "AFINITOR": 1.0080825744455142, "ALIMTA": 1.2807358586020796, "ALL": 1.3098526367469814, "AMIKACIN": 2.051119123426317, "AMINOSALICYLIC": 0.2461445283070846, "APIDRA": 0.3756575931615456, "APROVEL": 0.5294770593407456, "ARAVA": 0.2283774159517297, "ARIPIPRAZOLE": 0.2768234567226972, "ARIXTRA": 1.5144532993222102, "ASPARAGINASE": 1.2077744969888262, "ATAZANAVIR": 1.452581241708083, "ATRIPLA": 0.0143727835277434, "AUBAGIO": 0.1421727480067194, "AVANDIA": 0.1598066998731506, "AVASTIN": 1.5907453730072056, "AXITINIB": 4.787127700673955, "AZACITIDINE": 0.9576260209265024, "AZATHIOPRINE": 0.3582391739757994, "AZTREONAM": 2.050770917060521, "BARACLUDE": 2.002145938159553, "BAVENCIO": 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1.7831194205679906, "MEPOLIZUMAB": 0.3289266459717012, "MERCAPTOPURINE": 2.0733429737902336, "METFORMIN": 2.63039415612761, "METHOTREXATE": 1.6432633336526503, "MICAFUNGIN": 9.703154620030972, "MICARDIS": 6.409544555505026, "MIDAZOLAM": 0.7299765317932554, "MIRCERA": 1.4504244833981117, "MIXTARD": 1.834392063259952, "MULTAQ": 0.3279243349488224, "MYCAMINE": 3.0241408115384925, "MYCOPHENOLATE": 0.5448142957361366, "NEXAVAR": 8.49895943130735, "NOT": 2.731961783495609, "NOVONORM": 2.599755096988864, "NOVORAPID": 0.6408237258308126, "NOXAFIL": 2.9074267306114456, "NUBEQA": 6.281596871720396, "OBINUTUZUMAB": 1.012009710008423, "OFEV": 1.1830515540149684, "OLANZAPINE": 3.7477431263674426, "OLOPATADINE": 20.77731600369258, "OLYSIO": 2.22619695749173, "ONCASPAR": 0.6286118352162506, "OPDIVO": 8.778091511202947, "OPSUMIT": 0.4499489011491087, "PACLITAXEL": 4.07166048630619, "PANTOPRAZOLE": 0.1939952985227687, "PAZOPANIB": 5.457018408316558, "PEGASPARGASE": 2.9499715632230257, "PEGASYS": 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10.931019075800709, "VOTRIENT": 2.362625784607744, "XALKORI": 5.255674747529746, "XARELTO": 0.8787652119307506, "XELJANZ": 0.1317879880253344, "XELODA": 6.779865604880881, "XTANDI": 0.6266322610906426, "YERVOY": 0.6764317598301175, "YONDELIS": 3.702116887134036, "ZELBORAF": 0.8019002829946056, "ZONISAMIDE": 2.6465515709358494, "ZYPREXA": 1.614449149316158, "null": 2.51683480068649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5517.json
index 9fa24ce34ec..1aacce9dbc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5517.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5517.json
@@ -1 +1 @@
-{"ARAVA": 7.458853867128867, "CIMZIA": 20.74366818411284}
\ No newline at end of file
+{"ARAVA": 6.094136140217494, "null": 1.0969754771738236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5518.json
index 1ab919548d7..fe8c69cc548 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5518.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5518.json
@@ -1 +1 @@
-{"CIMZIA": 12.58621256834057, "COSENTYX": 44.25870098606173, "STELARA": 16.925933751935, "TREMFYA": 93.2330366114683}
\ No newline at end of file
+{"COMIRNATY": 0.1265829692979377, "ELIQUIS": 7.107023530844515, "null": 0.8307282216609648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5519.json
index c284d18f11b..06ac293c9cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5519.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5519.json
@@ -1 +1 @@
-{"null": 2.321372237564148}
\ No newline at end of file
+{"COMIRNATY": 0.2512995986557298, "NEXAVAR": 30.31547483983686, "null": 0.7692117648308936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/552.json
index 7750d4d54e8..f75c87834a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/552.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/552.json
@@ -1 +1 @@
-{"AVASTIN": 7.369900695043835, "BRILIQUE": 5.596485783634826, "CABOMETYX": 5.651897475790106, "ELIQUIS": 2.7745569954274245, "EVENITY": 43.391853880427526, "KEYTRUDA": 1.3983383413122303, "LENVIMA": 20.651641066753616, "NEXAVAR": 4.539225268954751, "ROACTEMRA": 12.181739776967426, "STELARA": 3.325574829564992, "SUTENT": 3.995738296764016, "XTANDI": 2.5107483294547484}
\ No newline at end of file
+{"COMBIVIR": 39.07619223461191, "null": 2.964743232056498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5520.json
index 861a69fb449..8c3f2d1dd1c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5520.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5520.json
@@ -1 +1 @@
-{"CHAMPIX": 4.251340436413179, "GARDASIL": 23.67095228854161, "MIRABEGRON": 112.2460116099052, "TOZINAMERAN": 1.1536266970344382, "XYREM": 49.08378363190105, "ZONISAMIDE": 118.88364804682072}
\ No newline at end of file
+{"SUTENT": 3.9360510525814494, "null": 0.4495171624950593}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5521.json
index d80cc33f176..bafa429822b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5521.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5521.json
@@ -1 +1 @@
-{"null": 3.0265595087464576}
\ No newline at end of file
+{"null": 1.007369280660236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5522.json
index e0300f34f1f..c3297000ad6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5522.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5522.json
@@ -1 +1 @@
-{"null": 6.810075230560672}
\ No newline at end of file
+{"ABRAXANE": 55.30702437836333, "ADENURIC": 16.328117200140913, "AFINITOR": 19.422934706136093, "ALPELISIB": 36.89639442563308, "APIXABAN": 6.530851119727518, "ARAVA": 0.5686868767303057, "ASPARAGINASE": 4.453349404255383, "AVASTIN": 3.20960163852152, "BYETTA": 6.904393071905728, "CAPECITABINE": 10.744089688597846, "CICLOSPORIN": 2.1667626424074737, "COMIRNATY": 0.0452795653852587, "COSENTYX": 1.0854252479849344, "CYMBALTA": 0.6493061411573208, "CYTARABINE": 3.3495688838688578, "DOCETAXEL": 4.083193753420265, "EVEROLIMUS": 13.903296751737496, "EXVIERA": 14.322785173136614, "FASLODEX": 8.231980579726653, "FULVESTRANT": 9.346337156297665, "HARVONI": 5.663877675850996, "IBRANCE": 2.000411061606712, "IPILIMUMAB": 4.6931242684799095, "JANUMET": 13.95923462273825, "JANUVIA": 9.830982992202497, "KALETRA": 4.611536250781388, "KEYTRUDA": 1.1115233074409805, "KISQALI": 8.380137348698895, "MEKINIST": 3.545110952534604, "NEXAVAR": 14.791776052853082, "OLYSIO": 8.933914118091076, "PEGASYS": 0.5049308003294334, "RIBAVIRIN": 5.493003906844376, "RIBOCICLIB": 24.1811488612435, "SPIKEVAX": 0.0578978410353596, "SUTENT": 1.257623983423834, "VOTRIENT": 2.4030685492749413, "XELODA": 9.691426315849826, "null": 0.5448508564748241}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5523.json
index 7328a2e7554..e2290ec9182 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5523.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5523.json
@@ -1 +1 @@
-{"null": 1.690422363166397}
\ No newline at end of file
+{"AFINITOR": 9.54421117217398, "BYETTA": 12.024211637252533, "CICLOSPORIN": 2.704948582400178, "COMIRNATY": 0.0708102227644367, "DEXAMETHASONE": 3.681153104708956, "EVEROLIMUS": 29.730763792722183, "HARVONI": 20.32763330193152, "JANUMET": 4.921646942681543, "JANUVIA": 10.065711819156355, "KEYTRUDA": 1.953852567642259, "NEXAVAR": 7.88935457435623, "PEGASYS": 3.794014914531565, "PEGINTRON": 3.5459208449778123, "STIVARGA": 5.137931716152903, "null": 0.6469720615616177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5524.json
index 6f2a188427d..a5494aa0475 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5524.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5524.json
@@ -1 +1 @@
-{"ACLIDINIUM": 7.64959702258826, "ADCIRCA": 4.0079430509532, "ADEMPAS": 6.332022762905129, "ADENURIC": 6.067665667193415, "AERIUS": 1.3115704421214924, "ALDARA": 2.02742515866795, "AMBRISENTAN": 8.602002550380435, "ANORO": 2.2816295670798845, "APROVEL": 1.0555334481574077, "AVAMYS": 19.63620574961391, "BENLYSTA": 1.8233752467407436, "BENRALIZUMAB": 5.706285634447246, "BEXSERO": 1.8065295874292144, "BUDESONIDE": 6.792136139986357, "CIALIS": 1.914194765068708, "COSENTYX": 1.7573233007801807, "DARZALEX": 3.133281544677238, "DUPIXENT": 3.884888540408189, "ENTYVIO": 1.5308448136014214, "ESBRIET": 1.0863336796198118, "EXFORGE": 1.1532181594728286, "FASENRA": 3.5571198197191483, "FLUCELVAX": 3.3694067415776763, "FLUTICASONE": 10.018999123764752, "GALAFOLD": 2.8220767946630883, "HUMIRA": 1.266396320714275, "IBRANCE": 1.3743079579278576, "IBUPROFEN": 1.1307555679195904, "INCRUSE": 1.5745764291037965, "INSULIN": 4.406263090470182, "KAFTRIO": 2.061211464050231, "KESIMPTA": 1.6555167398919814, "MACITENTAN": 4.351811208284828, "MEPOLIZUMAB": 7.530938140948781, "METHOTREXATE": 1.734856303756991, "NAGLAZYME": 4.184875841004458, "NUCALA": 11.98190999379069, "OFEV": 1.1782201813864812, "OMALIZUMAB": 7.723498960965423, "OPSUMIT": 7.082429166701621, "ORKAMBI": 2.2737378618230006, "RELVAR": 2.1806746573014086, "REVATIO": 2.088871531329061, "RIVAROXABAN": 3.8404634944945606, "RIXATHON": 4.475975245137927, "ROTATEQ": 1.787343118785627, "SILDENAFIL": 4.903028496670616, "SILODYX": 27.12149106958791, "SYNAGIS": 8.841466414948421, "TAMIFLU": 1.164594685083714, "TOZINAMERAN": 2.1810211268010526, "TRACLEER": 1.5619933868859932, "TRELEGY": 1.7708005542919671, "UROREC": 46.89901844546527, "VIAGRA": 4.3726339451933, "XELJANZ": 2.8640900645122964, "XOLAIR": 4.818888881202088, "ZOSTAVAX": 1.2293623753622267}
\ No newline at end of file
+{"ABACAVIR": 2.747350681839932, "ARAVA": 0.2164680593564865, "AVANDIA": 3.435162665874572, "BUDESONIDE": 1.4810921913893726, "BUSULFAN": 9.061903191280749, "CICLOSPORIN": 3.5112706387926127, "FENTANYL": 1.9770575201101503, "IBUPROFEN": 6.645869215485291, "NEXAVAR": 2.176164379130741, "PEGINTRON": 1.2517607510245017, "SOMATROPIN": 118.82859525466692, "SUTENT": 0.4534438633354836, "VIRAMUNE": 25.42466373157117, "null": 2.6063406130968927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5525.json
index e99007b3cc2..1f49b0f24dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5525.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5525.json
@@ -1 +1 @@
-{"AVAMYS": 27.4970156152809, "COSENTYX": 24.603209856284334}
\ No newline at end of file
+{"AFINITOR": 10.01006919845913, "CICLOSPORIN": 1.9917959963421887, "COMIRNATY": 0.0530974644539769, "DAKLINZA": 33.68786281065437, "FASLODEX": 12.642163649696869, "LANTUS": 4.419789336106967, "NEXAVAR": 4.138244583619787, "PEGASYS": 3.3080952244922788, "PEGINTRON": 3.539833829639244, "SUTENT": 1.5762897051775917, "VOTRIENT": 5.737294089541829, "null": 1.197751605047122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5526.json
index ad08a4c4d12..fd0151db097 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5526.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5526.json
@@ -1 +1 @@
-{"AFINITOR": 17.186241379549326, "MEPOLIZUMAB": 148.91171148216262, "OMALIZUMAB": 56.705455127876206}
\ No newline at end of file
+{"PEMBROLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5527.json
index 79ce8d48a0a..48b27a37b30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5527.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5527.json
@@ -1 +1 @@
-{"AVAMYS": 13.284000866359689, "BAQSIMI": 260.4657714333368, "CHAMPIX": 1.3340169990421, "CHLORHEXIDINE": 5.109512639514701, "COSENTYX": 1.298763644469326, "ENBREL": 2.612436676619505, "ENTRESTO": 1.5278387198516437, "IBRANCE": 1.3596169755315888, "MEPOLIZUMAB": 1.7799863346537823, "RELVAR": 7.073219053252065, "SUTENT": 2.9590174337254664, "TOZINAMERAN": 1.2187131290235262, "null": 2.231900859233242}
\ No newline at end of file
+{"AFINITOR": 2.646534367556543, "COMIRNATY": 0.5901347877457046, "ELIQUIS": 0.5889680118045116, "FORSTEO": 1.6008848803566416, "HARVONI": 5.623214282279865, "NEXAVAR": 1.0337598617673276, "OZEMPIC": 55.66682175376164, "PANTOPRAZOLE": 3.808013334838306, "PEGASYS": 8.362370050043396, "PEGINTERFERON": 3.140197980507461, "PEGINTRON": 4.081818816527785, "SPIKEVAX": 0.6806295337465021, "STELARA": 0.867234119030269, "SUBOXONE": 3.449977908525622, "SUTENT": 1.306162869518721, "TOZINAMERAN": 0.8573156885932687, "VAXZEVRIA": 0.6559466797787573, "XELJANZ": 1.1630985738689146, "null": 1.031768242413223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5528.json
index aab6c532e62..c106af618ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5528.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5528.json
@@ -1 +1 @@
-{"DOCETAXEL": 13.998010511142423, "IBRANCE": 2.0912241390637885, "MEPOLIZUMAB": 5.790630077018108, "NUCALA": 15.878804052461458, "SUTENT": 4.633536241178054, "null": 2.7592624802170604}
\ No newline at end of file
+{"NEXAVAR": 77.29630421893182, "null": 0.4972591599644708}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5529.json
index fa9baa8d1c2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5529.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5529.json
@@ -1 +1 @@
-{"AFINITOR": 1.5359378304361868, "AVAMYS": 10.621506202579573, "CHAMPIX": 1.258885990754893, "CIMZIA": 1.07361892830072, "COSENTYX": 3.827693385275481, "ELIQUIS": 1.0665883526261974, "IBRANCE": 2.674845603599179, "IBUPROFEN": 5.95751326992526, "JARDIANCE": 1.0072124960782811, "OPSUMIT": 2.3071541205084647, "PEGINTRON": 1.1784144418203626, "SUTENT": 4.625529522228055, "TOVIAZ": 8.477493313926937, "null": 1.8761708412491895}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/553.json
index f19f8e7d8fa..f151d286203 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/553.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/553.json
@@ -1 +1 @@
-{"COVID19": 11.339416126085275}
\ No newline at end of file
+{"ATOSIBAN": 364.09945230536647, "BUPRENORPHINE": 19.936950831729355, "COMBIVIR": 53.43388190337051, "TRACTOCILE": 1509.8887549805152, "null": 1.491444015087827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5530.json
index 6d07c5f9846..0d49d3f7af6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5530.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5530.json
@@ -1 +1 @@
-{"null": 1.5376831920133922}
\ No newline at end of file
+{"EXJADE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5531.json
index 9fe57ac3ef0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5531.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5531.json
@@ -1 +1 @@
-{"COMIRNATY": 3.026368624942601, "COVID19": 1.0313099231924572, "SPIKEVAX": 2.502915692613385, "VAXZEVRIA": 1.6345154365463688}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5532.json
index 421192c3121..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5532.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5532.json
@@ -1 +1 @@
-{"COSENTYX": 7.913814465870637, "null": 1.1218511647856668}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5533.json
index 9aa879d01ba..25b748fb874 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5533.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5533.json
@@ -1 +1 @@
-{"SUTENT": 5.564279729652812, "null": 1.701849862941616}
\ No newline at end of file
+{"ABACAVIR": 1.4732873098198551, "ABATACEPT": 0.822757390147144, "ABILIFY": 1.2952939084409232, "ACTOS": 4.235496209895322, "ACTRAPID": 4.572345449220898, "ADALIMUMAB": 0.1502307583068068, "AFINITOR": 1.1209384724347156, "APIDRA": 0.8170383014741885, "ARAVA": 2.3329469870494544, "ARIPIPRAZOLE": 0.9059906379050016, "ARZERRA": 17.234922817130382, "ASPARAGINASE": 9.348567678525148, "ATRIPLA": 0.0662026884342883, "AUBAGIO": 1.4336109164033184, "AVANDIA": 1.4184724873190682, "AVASTIN": 2.3761769506473835, "BEDAQUILINE": 1.6985356855811466, "BENLYSTA": 0.9275147222501392, "BETAFERON": 3.333658828091606, "BEVACIZUMAB": 2.272649865702409, "BIKTARVY": 4.072503965535388, "BUPRENORPHINE": 0.7753792745718664, "BYDUREON": 2.0102974545365, "BYETTA": 9.350644960948664, "CARFILZOMIB": 3.2251822089842617, "CELECOXIB": 3.020415781021836, "CELLCEPT": 0.7416004710119498, "CHAMPIX": 0.366946783161814, "CICLOSPORIN": 1.0131710808021095, "CIMZIA": 1.2884911063688078, "CLOPIDOGREL": 1.0360696519808346, "COMBIVIR": 5.560928095815048, "COMIRNATY": 0.1047880319906083, "COSENTYX": 3.133224206743468, "CRIXIVAN": 8.871254499605044, "CYMBALTA": 2.6678070703632946, "CYTARABINE": 2.2874937092487726, "DEXAMETHASONE": 0.4004008151575272, "DULOXETINE": 3.284158157640713, "EFAVIRENZ": 2.7406433723046995, "ELIQUIS": 0.5092280193187264, "ENBREL": 1.6773554833580706, "ENFUVIRTIDE": 24.90715761283308, "ENTRESTO": 0.5082838465930225, "ENTYVIO": 1.3886096641323455, "EPIVIR": 12.599659604994558, "ESBRIET": 0.904063061221741, "ESMYA": 7.925074418281881, "EUCREAS": 5.053654039446934, "EXFORGE": 1.630575086726732, "EXJADE": 0.6130839764805859, "FASLODEX": 1.1638138563693508, "FENTANYL": 0.4455720521174067, "FORSTEO": 0.3715567787367191, "FORXIGA": 1.7148171982889666, "GALVUS": 9.957790632863446, "GARDASIL": 0.2234510713323847, "HEPSERA": 4.225463456311646, "HUMALOG": 0.8357961464879596, "HUMIRA": 3.3410620984761707, "IBRANCE": 0.9050721516325844, "IBUPROFEN": 2.0216697672535373, "INSULIN": 1.642851058666553, "JAKAVI": 0.8610312073572455, "JANUMET": 8.213960265882875, "JANUVIA": 5.413213356394599, "JARDIANCE": 1.16912979247557, "KAFTRIO": 1.8014481360207837, "KALETRA": 1.6122139193420664, "KEPPRA": 0.4294338802053584, "KEYTRUDA": 0.4023852077676655, "LAMIVUDINE": 4.955490336452736, "LANTUS": 0.6443438890624574, "LYRICA": 0.681944376725787, "METFORMIN": 16.351750291338135, "METHOTREXATE": 4.714677839340835, "NORVIR": 5.292626917247405, "OLANZAPINE": 2.371628646515697, "OMALIZUMAB": 0.529213576825851, "ONCASPAR": 8.173486909472942, "PANTOPRAZOLE": 2.088047324100467, "PEGASYS": 1.5572717891602583, "PEGINTERFERON": 1.313463109953762, "PEGINTRON": 0.4902330055109804, "PREGABALIN": 3.5751547801585506, "REYATAZ": 3.8311509001919695, "RIBOCICLIB": 3.3403508294835342, "RINVOQ": 1.1161345251431498, "RITUXIMAB": 1.014690181311922, "ROACTEMRA": 1.4692961833191145, "SAXENDA": 3.3003074561353016, "SIFROL": 2.793041950447652, "SIMPONI": 0.805605571155228, "SPIKEVAX": 0.0695376006636772, "STELARA": 1.8535091077775336, "STRIBILD": 0.3766472093425547, "SUSTIVA": 13.683564925922584, "SUTENT": 0.4157836524343999, "TASIGNA": 0.9197981351413388, "TOZINAMERAN": 0.1387329930353972, "TRACLEER": 0.669980674704811, "TRULICITY": 1.9330764400129512, "TWINRIX": 1.971510213817771, "VAXZEVRIA": 0.0495377839307732, "VICTOZA": 3.895038146208304, "VOTRIENT": 0.5590529074353017, "XELJANZ": 1.4165740464659131, "XOLAIR": 0.4061029221681014, "ZERIT": 22.559685416350383, "ZOSTAVAX": 1.3894907252467732, "ZYPREXA": 9.316903275164472, "null": 1.1570845313917877}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5534.json
index 0f601593120..f2a993ef6da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5534.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5534.json
@@ -1 +1 @@
-{"null": 1.9147619606564508}
\ No newline at end of file
+{"VAXZEVRIA": 1.449764843599997, "null": 0.3528265731859907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5535.json
index 4173cfcb4c4..99c86c2c033 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5535.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5535.json
@@ -1 +1 @@
-{"AZILECT": 170.40505820682887, "null": 2.384665230385425}
\ No newline at end of file
+{"null": 2.1369066781231147}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5536.json
index 031785b5b26..b51a2e5b282 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5536.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5536.json
@@ -1 +1 @@
-{"null": 1.0786987957213037}
\ No newline at end of file
+{"null": 0.7922580778215401}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5537.json
index d0dbaef3e85..da7ea0a66ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5537.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5537.json
@@ -1 +1 @@
-{"null": 1.4418412080229217}
\ No newline at end of file
+{"SOLIRIS": 30.212448172203665, "VAXZEVRIA": 4.589592230855323, "null": 0.4547009427102871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5538.json
index b150c51eb30..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5538.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5538.json
@@ -1 +1 @@
-{"null": 1.4259831885118324}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5539.json
index dfc053e4689..be94b922d84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5539.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5539.json
@@ -1 +1 @@
-{"AVAMYS": 135.62439723234328, "BUDESONIDE": 15.042057198826114, "DARZALEX": 10.54799599864986, "MEPOLIZUMAB": 5.129680157424341, "NUCALA": 2.991981302186584, "VARENICLINE": 213.2398847970452, "null": 1.2681180301370691}
\ No newline at end of file
+{"CETUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/554.json
index 9f73e00f48c..da170a8e00a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/554.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/554.json
@@ -1 +1 @@
-{"null": 1.4030839804291255}
\ No newline at end of file
+{"ARAVA": 3.9938660172710536, "ATRIPLA": 2.719284791053432, "BYETTA": 23.2573218001352, "JANUMET": 20.21212411019014, "JANUVIA": 39.20223787633837, "TRUVADA": 4.215352552502857, "ZOSTAVAX": 5.040994189851421, "null": 0.3193519570500644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5540.json
index b303c5d1585..5b2ff3ebdbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5540.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5540.json
@@ -1 +1 @@
-{"AVAMYS": 13.542034530464951, "FLUTICASONE": 33.36753249121173, "NUCALA": 6.445652306026791, "OMALIZUMAB": 63.805634159832906, "SUTENT": 1.4373513089902863, "TASIGNA": 5.413016265413506, "TOZINAMERAN": 1.1802162194084962, "ZOSTAVAX": 2.6097134084408986, "null": 1.3580992220385444}
\ No newline at end of file
+{"ABACAVIR": 0.3459687837839666, "ABATACEPT": 0.8112367949219578, "ACLASTA": 5.182508495608797, "ADALIMUMAB": 2.3651738430337663, "AERIUS": 3.453882512780276, "AFINITOR": 0.4625370845856584, "ALEMTUZUMAB": 1.192105749803493, "ALIMTA": 1.8636136328567048, "AMIKACIN": 2.231844898558922, "AMINOSALICYLIC": 3.4421082558839657, "APROVEL": 2.614531253140855, "ARAVA": 1.162645470612347, "ARIPIPRAZOLE": 0.2431561231220752, "ASPARAGINASE": 0.6650516954883257, "ATAZANAVIR": 0.9835864835957008, "ATEZOLIZUMAB": 6.285285375742584, "ATRIPLA": 0.1377062314346048, "AUBAGIO": 0.697853113755401, "AVANDIA": 0.6939577037293919, "AVELUMAB": 5.186145496372268, "AXITINIB": 16.753390014848808, "AZATHIOPRINE": 2.644920217563348, "BAVENCIO": 4.956567357485743, "BEDAQUILINE": 7.728451731313643, "BETAFERON": 3.45065821253789, "BEVACIZUMAB": 0.3907971381537348, "BIKTARVY": 1.166933875001468, "BRAFTOVI": 1.565280143307236, "BRILIQUE": 1.044703216742897, "BRINTELLIX": 0.2265534085130054, "BUDESONIDE": 0.1139151958616095, "BUPRENORPHINE": 0.5215074398614399, "BUSULFAN": 0.9809914582306808, "BYETTA": 0.8563561149756378, "CABOMETYX": 0.7296691148762099, "CAELYX": 0.7204383129850684, "CANCIDAS": 2.1209667609712053, "CANNABIDIOL": 2.665927530092933, "CAPECITABINE": 0.7694333013164277, "CASPOFUNGIN": 1.073616934791368, "CELLCEPT": 1.0719676157396505, "CHAMPIX": 0.561880100154298, "CICLOSPORIN": 0.7851296012811531, "CIMZIA": 0.4736453174712709, "CLOPIDOGREL": 0.4768147995600643, "COAPROVEL": 3.042223633695545, "COMBIVIR": 5.510310798753819, "COMIRNATY": 0.0923613469574353, "COSENTYX": 0.1532561080532732, "COTELLIC": 3.553001960603466, "CRIXIVAN": 6.169405596624159, "CUBICIN": 1.8312338464879667, "CYMBALTA": 0.7981902757075693, "CYTARABINE": 0.8517933252027377, "DABRAFENIB": 2.43402874286642, "DELAMANID": 2.6335387304733926, "DEXAMETHASONE": 1.0543001599135324, "EFAVIRENZ": 1.901974617439265, "ELIQUIS": 0.4105423666218313, "EMTRICITABINE": 1.58354225222928, "ENBREL": 0.6637374291282994, 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4.316767633661138, "TASIGNA": 0.8490691628427531, "TEMODAL": 1.69746566433422, "THALIDOMIDE": 1.986591645447708, "TIVICAY": 4.701953903118595, "TOCILIZUMAB": 6.4978951201722825, "TOZINAMERAN": 0.1050230811511252, "TRACLEER": 1.6136004071835786, "TREMFYA": 0.5334048234653248, "TRIUMEQ": 3.0237708836892208, "TRULICITY": 0.483948340137058, "TRUVADA": 0.1148019535598427, "TWINRIX": 2.3696994369557247, "VAXZEVRIA": 0.0435973365067126, "VEKLURY": 2.9510362980985128, "VFEND": 3.4170283704533717, "VICTOZA": 1.401951057020464, "VILDAGLIPTIN": 7.64271220380885, "VIMPAT": 1.074344358648058, "VIRAMUNE": 28.122670851311444, "VIREAD": 1.422997901311506, "VORICONAZOLE": 2.4983580605679574, "VOTRIENT": 2.16004884432652, "XALKORI": 2.1524371245495257, "XARELTO": 0.9820173411337036, "XELJANZ": 0.338498837046506, "XOLAIR": 0.1584053819771613, "YERVOY": 8.581449838269881, "ZOSTAVAX": 0.184377261940896, "ZYPREXA": 1.2165084279650096, "null": 1.933437434623823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5541.json
index dee19fef29f..0e2e41bc199 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5541.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5541.json
@@ -1 +1 @@
-{"null": 1.2349194595918347}
\ No newline at end of file
+{"AMINOSALICYLIC": 9.863488948402903, "HUMALOG": 16.22699915260514, "TAMIFLU": 12.622450927110243, "TWINRIX": 97.06904459895983, "null": 1.1189441517100718}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5542.json
index b2e7b6bb632..9062dec95a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5542.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5542.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"PANTOPRAZOLE": 1129.6804875969242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5543.json
index fbf070b9875..8505b67a3a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5543.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5543.json
@@ -1 +1 @@
-{"ACLIDINIUM": 140.08611178974064, "ANORO": 7.378232226872656, "AVAMYS": 124.64345505077404, "BUDESONIDE": 65.25688218887255, "DEXAMETHASONE": 2.392485884452181, "EFAVIRENZ": 9.926621125720963, "FASENRA": 49.50810648472746, "FLUTICASONE": 37.75355804313354, "IBUPROFEN": 3.657189395413015, "LEVOFLOXACIN": 1.862733358750856, "MEPOLIZUMAB": 5.169910165821498, "METHOTREXATE": 11.946702211061604, "NUCALA": 86.50490277073048, "OMALIZUMAB": 15.993468344541697, "PANTOPRAZOLE": 15.022383563728509, "XOLAIR": 5.865389581311857}
\ No newline at end of file
+{"TWINRIX": 982.0740076246668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5544.json
index 81bc57b9831..15a79830737 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5544.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5544.json
@@ -1 +1 @@
-{"ENTRESTO": 5.141645180688413, "KEPPRA": 2.2751141661865315, "null": 3.157489095767474}
\ No newline at end of file
+{"BLOOD": 9765.233574728178, "null": 0.8882203550082645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5545.json
index ae529ee5d9b..1afd8fd63c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5545.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5545.json
@@ -1 +1 @@
-{"SUBOXONE": 86.29629797653344, "null": 1.2199126845533774}
\ No newline at end of file
+{"ABACAVIR": 1.6254223329148154, "ALEMTUZUMAB": 14.500811536370795, "ATRIPLA": 0.7400670412738362, "BARACLUDE": 68.1807118252519, "BEDAQUILINE": 6.192876186137739, "BIKTARVY": 5.74237078064502, "CELLCEPT": 7.060521090184976, "CICLOSPORIN": 4.451912094740669, "COMBIVIR": 9.94832876686307, "COMIRNATY": 0.02030579931138, "CYTARABINE": 5.271113976880163, "DEXAMETHASONE": 1.8282266830324492, "DOXORUBICIN": 29.3846056265272, "EMTRICITABINE": 20.994179313240178, "ENTECAVIR": 113.90205205799128, "EPIVIR": 15.767705158215668, "HEPSERA": 40.75201156813115, "HIZENTRA": 9.948954687832384, "HUMALOG": 1.1619012489244094, "HUMIRA": 2.1791827003331794, "LAMIVUDINE": 23.88655440692921, "MABTHERA": 12.968281761654218, "METHOTREXATE": 1.7098171755477969, "PEGASYS": 1.9648611549794333, "PRIVIGEN": 10.449094457891476, "RINVOQ": 3.7427343481723234, "RITUXIMAB": 16.72827038006642, "SIMPONI": 2.783373511160178, "STELARA": 1.9452441736197743, "STRIBILD": 2.094615756278807, "SUTENT": 0.4172698707634599, "TENOFOVIR": 66.05944286504219, "TREMFYA": 5.032967976391252, "TRUVADA": 0.5649564661875964, "TWINRIX": 13.811064000770486, "VEMLIDY": 66.57821702822208, "VIREAD": 8.142364790830603, "XELJANZ": 0.9274979330537928, "ZYPREXA": 1.9408680603699613, "null": 0.6986897828138765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5546.json
index 4b46c765b46..739475634c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5546.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5546.json
@@ -1 +1 @@
-{"CICLOSPORIN": 4.62945995029691, "NUCALA": 12.105649200767076, "ZOSTAVAX": 11.238121331867946, "null": 1.2854212117444073}
\ No newline at end of file
+{"HUMAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5547.json
index 6992c4dea11..f95e44f6cf5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5547.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5547.json
@@ -1 +1 @@
-{"null": 1.5030322087711956}
\ No newline at end of file
+{"HEPSERA": 191.44061970449027, "VEMLIDY": 1966.8875608376236, "VIREAD": 254.68624259722085, "null": 0.1624904426200326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5548.json
index 39dbfca7c84..3fcbac43eac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5548.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5548.json
@@ -1 +1 @@
-{"AVAMYS": 33.312940071794905, "SUTENT": 3.333255921609096, "null": 3.349460294629244}
\ No newline at end of file
+{"ADEFOVIR": 541.6693372279842, "BARACLUDE": 1452.9984802120198, "BIKTARVY": 11.023349431784432, "ENTECAVIR": 398.5147792574245, "HEPSERA": 338.42826030452915, "PEGASYS": 3.472633003225663, "TENOFOVIR": 193.33614043315708, "TRUVADA": 2.323754783340984, "VEMLIDY": 801.0197711433434, "VIREAD": 150.2480570451599, "null": 0.0704306450420842}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5549.json
index a666d4ba3e3..377af2efea7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5549.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5549.json
@@ -1 +1 @@
-{"null": 7.977247753518294}
\ No newline at end of file
+{"TWINRIX": 2031.5442067160168, "null": 0.6424162645682162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/555.json
index 24bfefc0e68..8ea8004e3aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/555.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/555.json
@@ -1 +1 @@
-{"ACLIDINIUM": 15.788116947577956, "ARANESP": 132.38306226231197, "AVANDAMET": 10.85419364374887, "AVANDIA": 17.233442658468967, "CLOPIDOGREL": 3.0412668697915946, "ELIQUIS": 3.0579891233273027, "ENTRESTO": 3.4958651742543574, "EXJADE": 3.64016087415864, "FORSTEO": 1.4956184485519306, "MEPOLIZUMAB": 6.979657621364519, "OPSUMIT": 2.2939467252497585, "TASIGNA": 4.972108266025858, "TRACLEER": 6.174466580238899, "ZOSTAVAX": 3.136761200754285, "null": 1.0134338878151468}
\ No newline at end of file
+{"SUBOXONE": 94.80203619700433, "null": 0.4335501018639234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5550.json
index c70e9bd5da4..e320b05daf3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5550.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5550.json
@@ -1 +1 @@
-{"null": 1.8275871714573335}
\ No newline at end of file
+{"null": 1.1380882761191795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5551.json
index a4ac83b734d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5551.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5551.json
@@ -1 +1 @@
-{"ARAVA": 6.783110762184133, "AVAMYS": 23.839769141132308, "BENLYSTA": 20.443250103552167, "PEGASYS": 3.2651175792031752}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5552.json
index 7716c595ff4..5f75ded41a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5552.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5552.json
@@ -1 +1 @@
-{"COMIRNATY": 3.616081865482766}
\ No newline at end of file
+{"ARAVA": 4.632415713392016, "HIZENTRA": 38.15186738197758, "HUMAN": 42.89750223661919, "KIOVIG": 119.908424629118, "PRIVIGEN": 208.7809434457605, "null": 1.0254015186941736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5553.json
index 4798141e40f..19e684bc3c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5553.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5553.json
@@ -1 +1 @@
-{"null": 2.703349121596609}
\ No newline at end of file
+{"HEPSERA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5554.json
index b5aea8c25f9..902e5b7eea5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5554.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5554.json
@@ -1 +1 @@
-{"ABATACEPT": 5.978449769229223, "ACETAMINOPHEN": 11.813667041060732, "ACLASTA": 1.5362395208870248, "ACTOS": 1.0085464052928004, "ADALIMUMAB": 1.0278123161966368, "ADEMPAS": 2.000140900098144, "AERIUS": 1.033318172932865, "AFINITOR": 1.0617938790983068, "AIMOVIG": 1.1957351836392924, "AMBRISENTAN": 1.5691296745474248, "ARAVA": 1.465624946048357, "AUBAGIO": 1.336268420162498, "AVAMYS": 1.249486565762395, "BELIMUMAB": 5.546520932349633, "BENLYSTA": 2.6154655047497246, "BENRALIZUMAB": 2.1134070196621866, "BETAFERON": 1.070574718971463, "BOSULIF": 1.2228325256258257, "CHLORHEXIDINE": 17.615527659664526, "CHOLESTAGEL": 8.868473638625566, "CIMZIA": 6.924987708275627, "CINRYZE": 1.4350586133717145, "COSENTYX": 4.428489005334835, "DAXAS": 6.79905919571834, "DESLORATADINE": 1.325865368590253, "DUPIXENT": 1.1384792517385378, "ENBREL": 2.0454432109076377, "ENTYVIO": 3.1134567434864557, "ERELZI": 1.5168780735684235, "ESBRIET": 2.228947970105952, "EVENITY": 1.1028651854879032, "FAMPYRA": 3.1290200671903023, "FASENRA": 2.591100415508424, "FLUCELVAX": 1.989394325262715, "HIZENTRA": 1.6053187744455382, "HUMIRA": 1.6748708292695524, "HYQVIA": 1.3666238559262431, "IBRANCE": 2.288907611738858, "INCRUSE": 2.213317363099767, "INFLECTRA": 3.1595228284850534, "INSULIN": 1.706673138999228, "KAFTRIO": 1.1682361966386856, "KALYDECO": 3.595319619163448, "KARVEA": 2.2712750421827206, "KESIMPTA": 8.46147952859894, "KISQALI": 1.1824134703546914, "LEFLUNOMIDE": 2.397072080088689, "LEMTRADA": 1.3879277698199932, "MACITENTAN": 1.9360213491518825, "MAVENCLAD": 4.2182235135714405, "MENVEO": 1.3946849674267543, "MEPOLIZUMAB": 5.766419129305357, "METHOTREXATE": 3.237274759043305, "MMRVAXPRO": 9.713547105587658, "NAGLAZYME": 7.123502353363376, "NIMENRIX": 1.1231443236155818, "NINLARO": 1.706442909531744, "NUCALA": 2.940658080063855, "OCRELIZUMAB": 4.949656553002624, "OMALIZUMAB": 5.157104851191668, "OPSUMIT": 2.012006443709877, "ORENCIA": 2.1688320068792786, "ORKAMBI": 2.8936978937871003, "OZEMPIC": 2.006059205063244, "PASIREOTIDE": 8.985880492502382, "PLEGRIDY": 2.9882076993329565, "PREVENAR": 1.970737478192756, "RAPAMUNE": 1.0700072371971616, "RELVAR": 3.448637728775523, "REMICADE": 1.3245278888075065, "REVATIO": 1.844560431173512, "REVLIMID": 1.176336969335914, "RINVOQ": 1.7670191113762557, "RITUXIMAB": 2.7828605520688083, "ROACTEMRA": 1.3144236358122248, "SEMAGLUTIDE": 3.130926206794654, "SIMPONI": 6.057701915236309, "SKYRIZI": 1.2513597936837233, "SOLIRIS": 1.327186528517881, "SPINRAZA": 2.170590741597012, "STELARA": 1.7983806055832643, "SYNAGIS": 5.781711385643718, "SYNFLORIX": 5.439428078260963, "TELMISARTAN": 4.014674871096902, "TOZINAMERAN": 1.1790477458576794, "TRACLEER": 1.016210911486087, "TRELEGY": 1.858017909491275, "TREMFYA": 1.649555849766671, "TWINRIX": 1.4551815975459117, "VELTASSA": 1.0702181585891952, "XELJANZ": 5.251160202437409, "XOLAIR": 3.508971402582956, "XYREM": 1.323351766303983}
\ No newline at end of file
+{"ENTECAVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5555.json
index 050c715f621..7a0951a36ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5555.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5555.json
@@ -1 +1 @@
-{"CICLOSPORIN": 137.52493547373126}
\ No newline at end of file
+{"AFINITOR": 1.6152784248911611, "BARACLUDE": 56.961362588635126, "BEVACIZUMAB": 12.334511336931543, "BIKTARVY": 3.928729798195381, "BORTEZOMIB": 29.34498032691541, "BUSULFAN": 5.719843764567004, "CARMUSTINE": 15.516634258955971, "CELSENTRI": 37.90994644162344, "CICLOSPORIN": 7.72026506472417, "COSENTYX": 1.1222686166929836, "CYTARABINE": 6.873191511730263, "DARZALEX": 4.779851875646584, "DEXAMETHASONE": 11.14655944281346, "DOXORUBICIN": 44.05824269346044, "ENTECAVIR": 137.78668538384193, "EPCLUSA": 9.815736919356604, "HARVONI": 30.71656075311177, "HEPSERA": 44.65817401307872, "JAKAVI": 9.474871024021782, "KEYTRUDA": 0.8328745192976439, "LAMIVUDINE": 30.03203632840066, "MABTHERA": 60.83092471733034, "MELPHALAN": 17.29619037851157, "METHOTREXATE": 7.568568022542653, "NEXAVAR": 2.228811547482642, "PEGASYS": 0.5843343819394713, "RIBAVIRIN": 14.056526656310446, "RITUXIMAB": 83.19623849410237, "SIMEPREVIR": 51.36221335161509, "SIMPONI": 1.8700507473586083, "SOVALDI": 24.750836315201404, "SUTENT": 0.6194235752069382, "TENOFOVIR": 90.9693594286036, "VIREAD": 14.49678923427908, "null": 0.3176379342297908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5556.json
index e0d4fa10bae..7c9c438f454 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5556.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5556.json
@@ -1 +1 @@
-{"ACOMPLIA": 1.1437136979110656, "ADEMPAS": 1.1919917104980864, "AGENERASE": 1.0971993508979798, "AIMOVIG": 1.1723559190287527, "AKYNZEO": 1.6266435306896103, "ALIGN": 1.5735425860121304, "ALYMSYS": 4.799154589596066, "AMINOSALICYLIC": 1.1220472857844093, "AVASTIN": 1.035288778674332, "BEMFOLA": 1.0251162346174183, "BEVACIZUMAB": 1.0398065120103763, "BOSULIF": 1.22930565304852, "BOTULINUM": 1.151304440903165, "BRAFTOVI": 1.2716826796749183, "BRINTELLIX": 3.9446164944480167, "BYDUREON": 1.36950520216406, "BYETTA": 1.3855800653056085, "CAPECITABINE": 1.1304451734603216, "CERVARIX": 1.412955623776125, "CHAMPIX": 2.3260723104196552, "CHORIOGONADOTROPIN": 1.668615716974, "CINACALCET": 1.756319479661293, "COMIRNATY": 1.6009697728131795, "CONSTELLA": 5.324444641354957, "COVID19": 2.5382042689332804, "CRIXIVAN": 1.013028974247033, "CYMBALTA": 1.4934274605192797, "DARBEPOETIN": 1.4075285179031982, "DELTYBA": 1.754676511697041, "DENOSUMAB": 1.3153487584263035, "DEXRAZOXANE": 1.3818961383244224, "DOCETAXEL": 1.073872367594665, "DULAGLUTIDE": 1.505485681378557, "EFFICIB": 1.3238121397096718, "ELLAONE": 2.1544969582757045, "EMEND": 1.0121195034533708, "EMTRICITABINE/TENOFOVIR": 1.305559016499643, "EPIRUBICIN": 1.4400997777844986, "ERBITUX": 1.0299603965262651, "ERENUMAB": 1.559333101157904, "ERIVEDGE": 1.114665949200337, "ESBRIET": 1.8203632779100285, "ESMYA": 1.1056546938674423, "EUCREAS": 1.1492500212734444, "EXENATIDE": 1.7243711067509129, "EXVIERA": 1.0035651570166162, "FABRAZYME": 1.3187640204489357, "FLEBOGAMMA": 1.593849677828558, "FLUCELVAX": 1.325361145025043, "FORSTEO": 1.7532013039697576, "FORTOVASE": 1.1412239112288205, "GARDASIL": 1.184361548978618, "GIOTRIF": 1.025846140173328, "GUANFACINE": 1.0452473433948737, "HYCAMTIN": 1.407160272149576, "IBRANCE": 1.0339420400765071, "ICANDRA": 1.2472659791113856, "INCIVO": 1.291629448477127, "INFERGEN": 1.1400400186487354, "IRINOTECAN": 1.8388548471081172, "ISTURISA": 1.9175445588431208, "KIOVIG": 1.544510945481931, "KISQALI": 1.3175725278333248, "LIRAGLUTIDE": 1.2039925218141931, "LONQUEX": 2.6557462838163506, "LONSURF": 2.018168492003554, "LUTATHERA": 1.405243651819472, "LUVERIS": 2.0954448636457466, "LYNPARZA": 2.780230261913804, "LYSODREN": 1.7166910475292587, "MIDOSTAURIN": 1.3516927082042427, "MIMPARA": 2.131888829471804, "MOVYMIA": 2.0920516768185573, "NERATINIB": 1.449999176658229, "NERLYNX": 1.2131010151169246, "NILEMDO": 1.493787006161303, "NIMENRIX": 1.7160938042585494, "NINLARO": 1.255177078181417, "NINTEDANIB": 1.924623217951238, "OFEV": 2.121303412956336, "OLAPARIB": 2.379809113658327, "ONIVYDE": 2.100997219578719, "OSSEOR": 1.0196069243265378, "OTEZLA": 1.9103398204268287, "OVITRELLE": 1.722707384395327, "OZEMPIC": 1.9180698654168105, "PEGINTERFERON": 1.0703122450579452, "PEMETREXED": 1.217550370972952, "PIRFENIDONE": 1.4918449768022233, "PREOTACT": 2.5397828714246398, "PRETOMANID": 1.428687043907312, "PRIVIGEN": 1.2968724556335045, "PROLIA": 1.153556964385795, "RADIATION": 1.1914044452439014, "RANEXA": 1.3949197504092514, "RAPISCAN": 2.129869984020443, "REGADENOSON": 2.3304190977873755, "RILUZOLE": 1.035943499862343, "RUBRACA": 2.2120777799631868, "RUCAPARIB": 1.3823352573147587, "RYBELSUS": 4.606891516615754, "RYDAPT": 1.9945544399512125, "RYEQO": 1.1205957355912728, "SACITUZUMAB": 2.032819325315852, "SAXENDA": 3.63326601514742, "SIGNIFOR": 1.7145562367534086, "SILGARD": 1.6200509896763886, "SITAGLIPTIN": 1.1933179545922106, "SOTORASIB": 1.1508444157555564, "SPIKEVAX": 1.833021304804497, "TAFINLAR": 1.095349273665308, "TALTZ": 1.07236753140649, "TEGAFUR": 1.4515106753077949, "TEPMETKO": 3.538019223047813, "TERIPARATIDE": 1.2070371386539127, "TERROSA": 2.087142972732305, "THERAPEUTIC": 1.5789829967686988, "TIGECYCLINE": 1.458356280454586, "TOZINAMERAN": 1.2815960856955737, "TRABECTEDIN": 1.110320643872979, "TREPROSTINIL": 1.3238121397096718, "TRIUMEQ": 1.1020428794301382, "TRODELVY": 1.3913852226487282, "TRULICITY": 3.913777695990481, "TWINRIX": 1.2443056336855822, "VARENICLINE": 1.0824043894902935, "VAXZEVRIA": 1.6070149092390695, "VICTOZA": 2.8462924962131986, "VORTIOXETINE": 2.431326558267716, "VOTRIENT": 1.3423745474996165, "WAKIX": 1.0755048934667502, "XALKORI": 1.6055205689671703, "XELODA": 1.611238719454459, "ZALVISO": 4.846605938473601, "ZEJULA": 1.3815363718594658, "ZELBORAF": 1.040341654767989, "ZEPATIER": 1.1724646014767173, "ZIAGEN": 1.7414426147706086, "ZYLLT": 1.04880323682569}
\ No newline at end of file
+{"TWINRIX": 2788.5962976576443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5557.json
index c7fc2f91051..7203116ab02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5557.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5557.json
@@ -1 +1 @@
-{"APIDRA": 3.485166423720468, "BENLYSTA": 1.971579547076381, "BUDESONIDE": 1.0955236593658892, "BYDUREON": 4.248315792012976, "ENTRESTO": 15.058884646759312, "FENTANYL": 2.0506677416020453, "IBRANCE": 1.1562553919451803, "INLYTA": 2.3266356243307924, "JARDIANCE": 2.1414185224319247, "LANTUS": 1.772248801923563, "LATUDA": 4.683636252556969, "LYRICA": 4.790857304035077, "SHINGRIX": 2.390199920178497, "TOZINAMERAN": 3.80713718278302, "TRELEGY": 11.41260392557306, "VIAGRA": 3.817954786452341, "XELJANZ": 2.683142016735039, "XTANDI": 1.104128925909931, "null": 2.149740922028582}
\ No newline at end of file
+{"HIZENTRA": 51.721159695051824, "HUMAN": 55.18924826040399, "PRIVIGEN": 194.94456465112216, "null": 1.2549764325881851}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5558.json
index 1dd2930576b..bd92808cf63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5558.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5558.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0505709444116795, "null": 1.2763921387255468}
\ No newline at end of file
+{"BEDAQUILINE": 93.71277875548957, "CICLOSPORIN": 9.271808028954329, "PEGASYS": 13.26700719516867, "null": 0.4040565412635927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5559.json
index 604d4524353..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5559.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5559.json
@@ -1 +1 @@
-{"ARAVA": 17.007863968389056}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/556.json
index 9cecd026769..36e571fa920 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/556.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/556.json
@@ -1 +1 @@
-{"null": 1.244470496613888}
\ No newline at end of file
+{"null": 0.955922073788854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5560.json
index 2c7447e8974..a3199879a2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5560.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5560.json
@@ -1 +1 @@
-{"BYDUREON": 14.330651041379928, "CYMBALTA": 2.0705669664758144, "HUMALOG": 5.253712110222016, "LANTUS": 2.133220001331121, "LYRICA": 7.539359501776247, "SUBOXONE": 8.733726617050294, "ZOSTAVAX": 2.794561064494443, "null": 1.6809012386972544}
\ No newline at end of file
+{"HIZENTRA": 50.47830427418024, "null": 0.5490418597259978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5561.json
index 4b214775bad..a505c34a9cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5561.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5561.json
@@ -1 +1 @@
-{"ARAVA": 1.9701337142699624, "CIMZIA": 2.8649195576462816, "PEGASYS": 1.020932426273596, "SIMPONI": 3.1235783360129656, "TOZINAMERAN": 2.782362586763087}
\ No newline at end of file
+{"ABACAVIR": 1.192182293013802, "AMINOSALICYLIC": 0.5451297258992881, "ATAZANAVIR": 0.7194417705444354, "ATRIPLA": 0.1836895074011037, "AZATHIOPRINE": 0.7856372861540105, "BEDAQUILINE": 2.311880269565149, "BIKTARVY": 1.3013981337423834, "BLOOD": 86.9189159251557, "BOCEPREVIR": 9.49460475171496, "BUPRENORPHINE": 2.6137588688842754, "CELLCEPT": 2.775190412407376, "CICLOSPORIN": 1.6502107008689408, "COSENTYX": 0.3070673278755901, "CYMBALTA": 0.3001948897045561, "DACLATASVIR": 192.08409143741375, "DAKLINZA": 154.85679920233505, "DASABUVIR": 40.50535812993751, "DESCOVY": 3.2448239462563198, "DEXAMETHASONE": 0.2037131729717672, "DOLUTEGRAVIR": 4.765148696447183, "DOXORUBICIN": 0.687621428507355, "ELIQUIS": 0.0787469907259164, "ENBREL": 0.327765360998109, "EPCLUSA": 135.3773960995886, "EPIVIR": 2.395455472995975, "EXJADE": 0.2516591272584069, "EXVIERA": 8.994358041029216, "FENTANYL": 0.4658299412103581, "HARVONI": 209.96740766911051, "HUMALOG": 0.7338908842486728, "HUMAN": 5.7721307846113294, "INCIVO": 2.138588627408528, "INTRONA": 1.6813160279730306, "JANUMET": 0.3450218183996446, "KALETRA": 0.6176995792381363, "LANTUS": 0.395501702635004, "LEDIPASVIR": 39.02832528485297, "MABTHERA": 1.1863603941504808, "MYCOPHENOLATE": 4.713906280729081, "NORVIR": 2.3846614160916837, "NOVOSEVEN": 2.0385591352302272, "NPLATE": 1.058466283832175, "OLYSIO": 119.83930948018384, "PEGASYS": 10.999716272042145, "PEGINTERFERON": 31.911282572903563, "PEGINTRON": 5.7032020278508, "REBETOL": 65.45724903225579, "REYATAZ": 3.097400349434636, "RIBAVIRIN": 298.6586198673844, "RITUXIMAB": 0.7226855722067822, "SIMEPREVIR": 234.90436308015376, "SIMPONI": 0.2742261184198309, "SOFOSBUVIR": 72.37544742557667, "SOLIRIS": 0.2695770301755926, "SOVALDI": 140.67988130454347, "STELARA": 1.2568156728080022, "STRIBILD": 0.2953931917698481, "SUBOXONE": 6.472257077760794, "SUTENT": 0.0589513816723058, "TOZINAMERAN": 0.0212851074362164, "TREMFYA": 0.9007563311415184, "TRUVADA": 0.1116298378035069, "VIAGRA": 0.4452740983059843, "XELJANZ": 0.1737612948970607, "ZEPATIER": 53.639794945656256, "ZOSTAVAX": 0.1461978126502991, "ZYPREXA": 1.1862827790225137, "null": 0.1548768034449895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5562.json
index 52e72f25822..da57299f04d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5562.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5562.json
@@ -1 +1 @@
-{"ABATACEPT": 1.99526122265236, "ACLASTA": 1.5908325713869471, "ADALIMUMAB": 1.003606885357384, "AIMOVIG": 2.473767578477926, "ANAKINRA": 6.03337410997935, "APREPITANT": 1.933581009562371, "BOTULINUM": 29.085627103859597, "BUPIVACAINE": 1.5282670146270378, "CELECOXIB": 1.1608884424376178, "CERVARIX": 3.2345181669802874, "COMIRNATY": 2.061385954454366, "COSENTYX": 2.583259689843464, "COVID19": 2.3557841345100403, "ERELZI": 2.2530732233966893, "ERENUMAB": 2.195195366040987, "EVENITY": 1.4469295549759404, "FIRDAPSE": 1.098336332533983, "FLEBOGAMMA": 1.8158540068115097, "FLUCELVAX": 1.7575254357000396, "FORSTEO": 1.6710409433242668, "GARDASIL": 2.330338741475777, "HUMIRA": 2.437523999855325, "LEFLUNOMIDE": 1.3694923416356708, "MENVEO": 2.168382562315345, "NIMENRIX": 3.660534437370429, "OCEAN": 15.72842707541396, "OCRELIZUMAB": 2.500260601103013, "PRIVIGEN": 2.193681865750557, "SHINGRIX": 2.0036743922054576, "SPIKEVAX": 1.722688431006661, "SPINRAZA": 1.5418826897218794, "TOZINAMERAN": 3.566426484498621, "TWINRIX": 1.3190023897325145, "VAXZEVRIA": 1.965996644099076, "ZARZIO": 2.236402243869809, "ZOSTAVAX": 1.803649276482544}
\ No newline at end of file
+{"OLYSIO": 530.1486413459464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5563.json
index c10949b4bbc..c81e0cb1d7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5563.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5563.json
@@ -1 +1 @@
-{"CIMZIA": 5.018470107156419, "LANTUS": 6.545261318096628, "SIMPONI": 6.978428468167049, "XELJANZ": 5.403019961580301, "ZOSTAVAX": 7.642698585987916, "null": 1.3596537672907174}
\ No newline at end of file
+{"OLYSIO": 68.92528886197735, "PEGASYS": 29.76771912571276, "PEGINTRON": 18.03834365547028, "RIBAVIRIN": 90.82319023474894, "SOVALDI": 76.9606002229754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5564.json
index 19c062499ae..6b836bbcea7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5564.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5564.json
@@ -1 +1 @@
-{"null": 2.387804269380746}
\ No newline at end of file
+{"PEGINTERFERON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5565.json
index c5348ba7582..226e71ee95e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5565.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5565.json
@@ -1 +1 @@
-{"AFINITOR": 2.6043610037800784, "ATRIPLA": 1.024134079187984, "CELLCEPT": 2.028655164016316, "CICLOSPORIN": 3.5087481883914693, "CLOPIDOGREL": 1.4322328745263475, "CYTARABINE": 2.7619128609137733, "DEXAMETHASONE": 3.0226152572819998, "EFAVIRENZ": 20.821467831672688, "ELIQUIS": 1.3528066641529586, "ENOXAPARIN": 4.679541487408792, "FENTANYL": 1.4264449383419278, "FORXIGA": 4.569749567753556, "JAKAVI": 2.7559405163344635, "JARDIANCE": 3.0995234714103725, "KEYTRUDA": 1.2559513328329048, "NOVOSEVEN": 15.89311978233603, "ROACTEMRA": 2.748543957606701, "SUTENT": 1.4267391289584497, "TASIGNA": 5.092873782852443, "VOTRIENT": 1.981854897057111, "null": 1.5148468453559707}
\ No newline at end of file
+{"DAKLINZA": 151.8364867932985, "EPCLUSA": 115.41334055001042, "HARVONI": 49.2195562710512, "PEGASYS": 17.49627553969152, "RIBAVIRIN": 204.29920361086772, "SOVALDI": 259.072465501785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5566.json
index 5983c5a0b38..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5566.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5566.json
@@ -1 +1 @@
-{"LEVETIRACETAM": 50.15914745594712, "null": 2.1840310555248794}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5567.json
index 24596d0eae2..7527837189c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5567.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5567.json
@@ -1 +1 @@
-{"null": 3.608846172111333}
\ No newline at end of file
+{"null": 1.3217361602779802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5568.json
index 0e7217b17b3..19e684bc3c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5568.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5568.json
@@ -1 +1 @@
-{"null": 1.7577431229335871}
\ No newline at end of file
+{"HEPSERA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5569.json
index 46a48d57fc7..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5569.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5569.json
@@ -1 +1 @@
-{"AVASTIN": 14.715574417008808, "CELECOXIB": 11.003400090320032, "CICLOSPORIN": 6.421113608871963, "EMPAGLIFLOZIN": 26.727844286177287, "FORXIGA": 13.160895997716914, "INVOKANA": 48.16911737572099, "JARDIANCE": 75.1263403376006, "KEYTRUDA": 2.362435914068973, "METHOTREXATE": 2.4599786724159647, "MYCOPHENOLATE": 14.529584344702911, "PEGASYS": 1.098369657754427, "PEGINTRON": 3.515391834048868, "ROACTEMRA": 17.436429214243372, "SOLIRIS": 3.525176853769997}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/557.json
index adbdb9658d9..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/557.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/557.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 6.214309686572341, "ELIQUIS": 3.102813577899986, "NOVOSEVEN": 74.40118164937415, "VAXZEVRIA": 2.153995138068192}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5570.json
index a92a33f14e0..99cb82d985a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5570.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5570.json
@@ -1 +1 @@
-{"KEYTRUDA": 15.268277178365915}
\ No newline at end of file
+{"PEGASYS": 40.57473560326963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5571.json
index 8c46cc6f04f..4bbb1e35fff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5571.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5571.json
@@ -1 +1 @@
-{"JARDIANCE": 17.155465778462478, "null": 1.4511030014567503}
\ No newline at end of file
+{"DAKLINZA": 65.79974705440259, "EPCLUSA": 198.68358075290303, "HARVONI": 145.48517654250932, "OLYSIO": 43.4134411319507, "PEGASYS": 11.618981624459783, "RIBAVIRIN": 208.4716387124404, "SOVALDI": 55.05430937726681, "null": 0.362810089380595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5572.json
index cbba94d881e..b75ecbb34e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5572.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5572.json
@@ -1 +1 @@
-{"ZOSTAVAX": 24.194802752771867}
\ No newline at end of file
+{"CICLOSPORIN": 16.621191428146737, "COMIRNATY": 0.1134131948299251, "MYCOPHENOLATE": 46.77960080420841, "RIBAVIRIN": 23.013618978041563, "RINVOQ": 20.153480267784808, "ROACTEMRA": 10.952167043308764, "null": 0.3085765402348511}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5573.json
index 9dc62f0ad30..faa6172baa6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5573.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5573.json
@@ -1 +1 @@
-{"null": 1.5056734221207937}
\ No newline at end of file
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5574.json
index e299f417513..3a1e4dbb2e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5574.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5574.json
@@ -1 +1 @@
-{"JARDIANCE": 176.97175248692744}
\ No newline at end of file
+{"VIREAD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5575.json
index 6178e263c1b..b0c7925e37f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5575.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5575.json
@@ -1 +1 @@
-{"EMEND": 1640.8684551118154}
\ No newline at end of file
+{"PEGASYS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5576.json
index d4e2dc2429d..e576ce3751b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5576.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5576.json
@@ -1 +1 @@
-{"AFINITOR": 6.743415216481868, "AIMOVIG": 8.790527182282677, "ARANESP": 1.1658093148397215, "BYDUREON": 37.59307232454269, "CIMZIA": 5.281202013630307, "COSENTYX": 6.358657303781159, "DULOXETINE": 2.8460085412569383, "ENOXAPARIN": 3.114255613552546, "EVEROLIMUS": 7.632344285518537, "FASENRA": 6.533851924653591, "INHIXA": 146.14435753282967, "LANTUS": 2.0471796439686023, "LEVEMIR": 2.6686461125603103, "NOVORAPID": 3.167046360729976, "PANTOPRAZOLE": 6.658691855814617, "PROPRANOLOL": 8.186647474042685, "ROACTEMRA": 7.48149772967829, "SIMPONI": 30.787679840954063, "STELARA": 14.151751896262011, "TOUJEO": 6.434243098805027, "TREMFYA": 73.62159192129377, "XOLAIR": 6.233384332184372, "null": 2.0235578051964285}
\ No newline at end of file
+{"ABILIFY": 0.6567341102009064, "ARAVA": 0.1758308357697139, "AVANDIA": 1.303100338433027, "BRILIQUE": 1.535863792261393, "BUSILVEX": 14.783695190770024, "CARMUSTINE": 6.311460372249967, "CICLOSPORIN": 0.4227965418192794, "CLOPIDOGREL": 1.380608842926797, "COAPROVEL": 2.6657284095909115, "COMBIVIR": 2.4135491630461425, "COMIRNATY": 0.1475911265546036, "CYMBALTA": 0.511552972091702, "DEXAMETHASONE": 1.109429745455419, "ELIQUIS": 0.3239555241834423, "EXJADE": 0.7890250313044535, "FEBUXOSTAT": 11.846524798139164, "FENTANYL": 0.6416437526292346, "IBUPROFEN": 1.3351364362623144, "IPILIMUMAB": 2.208515980355958, "ISENTRESS": 2.999909162521497, "JANUMET": 4.259514955805113, "JANUVIA": 0.7676365523354824, "JARDIANCE": 0.436018998653787, "KALETRA": 2.928877671509451, "KEPPRA": 2.1477852284715166, "KEYTRUDA": 1.466977590719134, "KISQALI": 3.785607562912243, "LEVETIRACETAM": 1.9825155817597044, "LEVOFLOXACIN": 4.615930768339785, "LYRICA": 0.982029370041992, "METHOTREXATE": 1.246507803187083, "MICARDIS": 2.887395841901769, "MULTAQ": 3.964794264298266, "NEXAVAR": 2.626900605097561, "OLANZAPINE": 0.9520411063288384, "OLYSIO": 4.657834937980569, "OPDIVO": 2.721252679289698, "PEGASYS": 0.5341373638490212, "PLAVIX": 1.9720728157859413, "REYATAZ": 7.743430362215176, "SAXENDA": 1.581157536436154, "SPIKEVAX": 0.0742616727569832, "STELARA": 0.4554803421943927, "STIVARGA": 1.1306663799978565, "SUBOXONE": 1.5133095351418144, "SUTENT": 0.3683206637449214, "TAMIFLU": 5.5508965781441, "TOZINAMERAN": 0.0589311839870626, "VAXZEVRIA": 0.0292335622914049, "VFEND": 1.344501198868599, "VIRAMUNE": 9.148280883816811, "VOTRIENT": 1.899754792177533, "ZYPREXA": 1.154711016022527, "null": 2.8871367941517523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5577.json
index 7ad99d3fa62..8402583e368 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5577.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5577.json
@@ -1 +1 @@
-{"null": 4.893428407223816}
\ No newline at end of file
+{"null": 1.3588467267129662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5578.json
index 7174ba45eda..b3be423fdde 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5578.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5578.json
@@ -1 +1 @@
-{"BRIDION": 354.81312716219105, "DEXAMETHASONE": 31.14163769891865, "FENTANYL": 56.00423894665031}
\ No newline at end of file
+{"AERIUS": 3.1581863863512094, "ALIMTA": 1.218563718217731, "APROVEL": 3.6148948053102288, "ARANESP": 0.8198016063174527, "ARAVA": 0.1116530049220036, "ASPARAGINASE": 1.536205815777481, "AZATHIOPRINE": 2.364313316236609, "BRILIQUE": 2.2985120606209115, "CAELYX": 2.79778209103456, "CANCIDAS": 5.708432239383474, "CELLCEPT": 2.17380807002108, "CICLOSPORIN": 0.6544944288195538, "CLOPIDOGREL": 1.0814589430142083, "COAPROVEL": 6.317337393354136, "COMIRNATY": 0.0254820469202418, "CRIXIVAN": 5.051583375314272, "CYMBALTA": 0.3327459742565863, "CYTARABINE": 1.6886858962639266, "DARUNAVIR": 11.779982094125865, "EFAVIRENZ": 8.67736550825753, "ELIQUIS": 0.4828191195115399, "ENOXAPARIN": 2.746997486148972, "EPIVIR": 6.619742538631544, "ESOMEPRAZOLE": 5.173272214966265, "FENTANYL": 0.6604871407398127, "GANCICLOVIR": 3.1528992255001183, "GLIBENCLAMIDE": 5.460949687430225, "IBUPROFEN": 2.32192566387324, "KALETRA": 1.434851868675726, "KEPPRA": 1.896907938073791, "KEYTRUDA": 0.5603690304712756, "LEVOFLOXACIN": 1.766729801099482, "METHOTREXATE": 0.5485895404989953, "NEXAVAR": 0.6140165969920498, "NOVONORM": 7.083807913223398, "NOXAFIL": 4.309402186794785, "OLANZAPINE": 0.5308971242430608, "OPDIVO": 0.843208468613559, "PANTOPRAZOLE": 8.28116460083992, "PEGASYS": 0.2931240987946363, "PEGINTERFERON": 1.067680044558734, "PEMBROLIZUMAB": 1.6994425152252564, "PLAVIX": 1.522713862853813, "PRADAXA": 5.7946689001960126, "TAMIFLU": 2.060264767255891, "TRACLEER": 1.6545390155045072, "VFEND": 4.177332069915817, "VIAGRA": 0.8163115969097631, "VIRAMUNE": 21.38444524199395, "VORICONAZOLE": 4.952749714864956, "XARELTO": 2.341395234823331, "ZYPREXA": 0.8073465490589999, "null": 4.641642150024873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5579.json
index f989a5f311b..4bcb1f1ec07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5579.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5579.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 336.35450396468894}
\ No newline at end of file
+{"PEGINTERFERON": 51.8312100964621, "null": 0.7092780897017376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/558.json
index 2d66adec518..16aefc1b5c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/558.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/558.json
@@ -1 +1 @@
-{"null": 2.2450342229325893}
\ No newline at end of file
+{"COMIRNATY": 0.2172794246331278, "VAXZEVRIA": 0.5468382120215953, "null": 1.6029054922303072}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5580.json
index d7c259c050c..002dce46edf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5580.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5580.json
@@ -1 +1 @@
-{"ABILIFY": 3.763533281688927, "ARIPIPRAZOLE": 5.534869683783612, "BRINTELLIX": 25.698832995465622, "CHAMPIX": 34.82197659870145, "CYMBALTA": 3.512676521934172, "KEPPRA": 4.214585880133037, "LATUDA": 12.210437613776168, "PEGASYS": 1.4291626627540723, "null": 1.8078731685296332}
\ No newline at end of file
+{"CANCIDAS": 21.26528082258209, "CELLCEPT": 1.534000499972357, "CICLOSPORIN": 0.6965281216188584, "COMIRNATY": 0.0232904141326033, "DOXORUBICIN": 3.974093012982332, "EPIVIR": 10.874454746272315, "FENTANYL": 1.484891670643012, "FUZEON": 196.6941678065769, "KEYTRUDA": 2.54636020010749, "LEVOFLOXACIN": 1.5462080800582902, "MICARDIS": 4.730046383830578, "NEXAVAR": 2.154395045709915, "OPDIVO": 4.283665611637545, "PEGASYS": 0.7149712218821701, "PEGINTRON": 1.2816529202405416, "PLAVIX": 2.526990123689311, "STIVARGA": 7.0359841607686455, "SUTENT": 0.9221091376465672, "TAMIFLU": 18.87629302680123, "VFEND": 5.112324998761247, "VIRAMUNE": 33.2294897419774, "null": 2.7446841056587585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5581.json
index d185c4bb324..24b65598973 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5581.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5581.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 22.98890708770908, "OLANZAPINE": 30.977487753246205, "null": 2.0412460480762418}
\ No newline at end of file
+{"COMIRNATY": 0.6057179229290024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5582.json
index 7cb2aad75df..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5582.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5582.json
@@ -1 +1 @@
-{"CARIPRAZINE": 3436.650574946053}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5583.json
index 8e8c80e45b6..048f42cf349 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5583.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5583.json
@@ -1 +1 @@
-{"null": 2.1706108345009483}
\ No newline at end of file
+{"null": 2.2434296420663644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5584.json
index ebdd432cd92..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5584.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5584.json
@@ -1 +1 @@
-{"null": 2.856126191322969}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5585.json
index 769acd262c0..608549aa93b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5585.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5585.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 6.225551588790206, "FENTANYL": 22.532570472543192, "null": 4.093710481331146}
\ No newline at end of file
+{"ABACAVIR": 1.3065138882831682, "ARAVA": 0.5942751032412774, "BEDAQUILINE": 24.049799982381305, "BRILIQUE": 4.816664012575751, "CHAMPIX": 0.8731805823090548, "COMIRNATY": 0.0307783431568511, "CYMBALTA": 0.6879061650209066, "DELAMANID": 24.296871103636636, "ERLOTINIB": 101.07373888247392, "IBUPROFEN": 2.314175832170516, "ISENTRESS": 6.900403193211755, "LEVOFLOXACIN": 2.9226748246634866, "MULTAQ": 6.139875882219048, "PEMBROLIZUMAB": 3.760940600477056, "SUTENT": 0.4759605202945477, "VIRAMUNE": 18.58154531849236, "VOTRIENT": 2.0525038160155784, "ZYPREXA": 1.3675739952248984, "null": 2.922742397700114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5586.json
index d7f286c3a9d..858672e8b8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5586.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5586.json
@@ -1 +1 @@
-{"SUBOXONE": 55.03731513097423, "null": 1.120368689581554}
\ No newline at end of file
+{"CICLOSPORIN": 8.714510338289603, "COMIRNATY": 0.1661362174152566, "null": 0.9849843623000544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5587.json
index 29f4bd6a69c..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5587.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5587.json
@@ -1 +1 @@
-{"VIGABATRIN": 2147.1499701144967, "null": 3.1287473158599246}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5588.json
index c330423c0dd..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5588.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5588.json
@@ -1 +1 @@
-{"AMIKACIN": 1321.3792121936094, "null": 1.1228291695147434}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5589.json
index 02b639386e9..495fc394388 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5589.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5589.json
@@ -1 +1 @@
-{"null": 3.87893833691815}
\ No newline at end of file
+{"null": 2.9341242589086303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/559.json
index a109b19bf72..982b8b5c88c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/559.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/559.json
@@ -1 +1 @@
-{"ENTRESTO": 17.68778272181648}
\ No newline at end of file
+{"CARBIDOPA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5590.json
index b979eaf3e6a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5590.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5590.json
@@ -1 +1 @@
-{"FENTANYL": 37.92941563518856, "SUBOXONE": 48.67233379313334, "null": 2.6325165099319694}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5591.json
index eecb0657df7..7565cc15c32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5591.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5591.json
@@ -1 +1 @@
-{"ATOSIBAN": 1996.5794647630812}
\ No newline at end of file
+{"null": 0.9120026232315974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5592.json
index 06bb368801a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5592.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5592.json
@@ -1 +1 @@
-{"null": 1.872168776398728}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5593.json
index 883c813b2d1..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5593.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5593.json
@@ -1 +1 @@
-{"null": 3.0041773045320355}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5594.json
index f5b5aec6a8c..46ca16009f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5594.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5594.json
@@ -1 +1 @@
-{"null": 3.6264816480187143}
\ No newline at end of file
+{"null": 1.5859616200385516}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5595.json
index 4926b1901dc..9b1ad37230b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5595.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5595.json
@@ -1 +1 @@
-{"null": 3.3399747004831646}
\ No newline at end of file
+{"BARACLUDE": 27.412576373237403, "CABOMETYX": 23.981351824918622, "CABOZANTINIB": 29.996389152386485, "CELLCEPT": 0.9391082107491696, "CICLOSPORIN": 1.2676942997666587, "COSENTYX": 0.6157070082305502, "DACLATASVIR": 58.54203475195683, "DAKLINZA": 55.46603061317785, "ENTECAVIR": 9.974535134057517, "EPCLUSA": 28.278685580557507, "EXVIERA": 23.950892692541142, "GLECAPREVIR": 577.3223763570121, "HARVONI": 58.42611373237201, "HEPSERA": 12.485046651037486, "INCIVO": 2.581830366445286, "JANUVIA": 0.8206122397585822, "NEXAVAR": 523.0707210796588, "OCALIVA": 2.697551802508707, "OLYSIO": 20.56345777099131, "PEGASYS": 2.308174788477719, "PEGINTERFERON": 6.808505291656262, "PEGINTRON": 2.463860480363384, "REBETOL": 13.099374481068653, "REGORAFENIB": 24.1944534690259, "RIBAVIRIN": 21.61363963307781, "SOFOSBUVIR": 23.772727215694548, "SORAFENIB": 45.14421136202953, "SOVALDI": 48.2368636220552, "STELARA": 0.5779375827696339, "STIVARGA": 17.792609847090493, "VEMLIDY": 23.079483594531577, "VIREAD": 2.336098690931376, "null": 0.0527878358326763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5596.json
index 05298a18ebf..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5596.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5596.json
@@ -1 +1 @@
-{"null": 1.84449607237132}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5597.json
index d21d25573f9..426384360df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5597.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5597.json
@@ -1 +1 @@
-{"null": 3.018048574023795}
\ No newline at end of file
+{"OLYSIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5598.json
index ce765b1ec06..8743daede6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5598.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5598.json
@@ -1 +1 @@
-{"null": 1.967405165801844}
\ No newline at end of file
+{"ALIMTA": 4.678925388619213, "ARAVA": 0.2715575460203048, "AUBAGIO": 1.8665079652998524, "AVANDIA": 1.2468913868634248, "BUSULFAN": 1.5573384766073557, "CANCIDAS": 8.888129809789534, "CLOPIDOGREL": 1.4246549785514795, "COMIRNATY": 0.0395690683413073, "CYMBALTA": 1.1010874775473112, "CYTARABINE": 1.1154024258951258, "DEXAMETHASONE": 1.160623550594371, "EFAVIRENZ": 9.157881187549656, "ELIQUIS": 0.2983794984984989, "ENOXAPARIN": 4.33394043791073, "ESOMEPRAZOLE": 4.236129141174011, "EXJADE": 1.3143085914556114, "GILENYA": 17.182159324512153, "IBUPROFEN": 1.362444206494133, "ISENTRESS": 4.15439197129471, "JANUMET": 0.922106399318404, "JANUVIA": 1.163800801522128, "KAFTRIO": 5.457276526512403, "KALETRA": 7.006693446318263, "KEPPRA": 1.2511690942953373, "KEYTRUDA": 0.4141788661140401, "KISQALI": 3.398997123160076, "LEVETIRACETAM": 1.138183287306786, "LEVOFLOXACIN": 2.526827806843849, "LYRICA": 0.9477131199867004, "METHOTREXATE": 2.275515237003312, "MICARDIS": 3.5319344169338973, "MULTAQ": 59.06876295073005, "NEXAVAR": 0.6639860021016407, "OLANZAPINE": 1.905988755253268, "OPDIVO": 1.256704596673505, "PEGASYS": 0.2905827259493488, "PLAVIX": 2.4151047445550007, "ROACTEMRA": 3.942931084805762, "SPIKEVAX": 0.0297766843188954, "SUTENT": 0.2529184747309022, "TAMIFLU": 1.6871027421688294, "TEMODAL": 6.298118991076426, "VEKLURY": 13.326218985502637, "VFEND": 7.002793572595037, "VORICONAZOLE": 3.2712058524857826, "VOTRIENT": 1.8178038584416565, "ZYPREXA": 1.9184724212229909, "null": 2.8969783301411085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5599.json
index 65482cd981e..33344de9de4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5599.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5599.json
@@ -1 +1 @@
-{"null": 2.4593523396094774}
\ No newline at end of file
+{"CLOPIDOGREL": 32.11859324482533, "null": 0.5244050423572348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/56.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/56.json
index 3fec00b881c..c3fa1e0c3a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/56.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/56.json
@@ -1 +1 @@
-{"CICLOSPORIN": 11.732023580390669, "JANUMET": 16.12936836817677}
\ No newline at end of file
+{"null": 4.266278772784978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/560.json
index 3ef95d64199..04c99124262 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/560.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/560.json
@@ -1 +1 @@
-{"AVANDIA": 7.269905223714561, "ELIQUIS": 20.85058312823719, "MEPOLIZUMAB": 8.870624782641633, "PLAVIX": 3.2401241714763445, "null": 1.6585260349856672}
\ No newline at end of file
+{"INSULIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5600.json
index c8f5ae6770a..d980354f33f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5600.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5600.json
@@ -1 +1 @@
-{"FENTANYL": 26.817869729866047, "LEVETIRACETAM": 19.13978505224685, "null": 3.631418343302053}
\ No newline at end of file
+{"ABACAVIR": 1.1332225434007197, "AFINITOR": 1.4786572739814876, "AMINOSALICYLIC": 2.5190760484170025, "ARANESP": 0.883579707624603, "ARAVA": 0.2339745470789906, "ASPARAGINASE": 6.178761764269764, "ATAZANAVIR": 2.527580901033091, "ATRIPLA": 0.1404280884336449, "AUBAGIO": 0.7199587130146802, "AVANDIA": 1.449783548260862, "BEDAQUILINE": 3.302878975172696, "BENLYSTA": 0.9608863086078664, "BUSULFAN": 6.594300686592269, "BYETTA": 1.3643253383531944, "CICLOSPORIN": 2.869563264668373, "COMIRNATY": 0.097834407510981, "COSENTYX": 0.9109810774525912, "CRIXIVAN": 4.296713476066761, "CYMBALTA": 0.8345877844156671, "CYTARABINE": 4.042389901088626, "DEXAMETHASONE": 2.2113502370405502, "EFAVIRENZ": 8.419660048653052, "ELIQUIS": 0.3517273064019648, "EMTRICITABINE": 4.723320937088181, "ENBREL": 1.043549086331478, "EPIVIR": 8.620628971074215, "EXJADE": 4.8437052723761695, "FASLODEX": 1.358830790357239, "FENTANYL": 0.5071100485036613, "GANCICLOVIR": 3.848120487977617, "GARDASIL": 0.8024737137894048, "GLIVEC": 6.477623546234107, "HUMALOG": 0.495851235116463, "IBRANCE": 0.3493468490147505, "IBUPROFEN": 3.111446480438999, "ICLUSIG": 2.1754795957608533, "INSULIN": 2.376032115493568, "INVIRASE": 20.812618482064707, "JAKAVI": 6.643179267591862, "JANUMET": 2.839970895133616, "JANUVIA": 1.5319338505254425, "KALETRA": 4.778546246777942, "KEPPRA": 0.501397094617346, "KEYTRUDA": 0.3031094506499208, "KYMRIAH": 3.8070722932632046, "LAMIVUDINE": 24.622710880008647, "LANTUS": 0.8259409342869668, "LEVETIRACETAM": 1.9853602153562304, "LEVOFLOXACIN": 1.6631559854534963, "MEKINIST": 1.4597095345486804, "METHOTREXATE": 1.1630124438299303, "NEXAVAR": 1.416612017403328, "OCALIVA": 5.031470260330458, "OPSUMIT": 1.1250033207732144, "OZEMPIC": 24.45373386216384, "PANTOPRAZOLE": 2.65942611665106, "PEGASYS": 1.5814919856293153, "PEGINTRON": 0.9571926322662136, "RITUXIMAB": 1.1264150570083824, "SOLIRIS": 2.017432548750733, "SOMATROPIN": 11.912783809452428, "SPIKEVAX": 0.0809768641753084, "SPRYCEL": 1.2973378446607058, "STELARA": 0.3599800755340109, "STIVARGA": 0.8935959730605031, "SUBOXONE": 1.0837602934801225, "SUTENT": 0.8970928284099116, "TASIGNA": 1.4696569603062468, "TOZINAMERAN": 0.1858715030492342, "TRACLEER": 3.3072012109477136, "VAXZEVRIA": 0.0292754638322116, "VFEND": 1.4792677286217653, "VOTRIENT": 0.7981864341621582, "XELJANZ": 0.402251646182594, "XOLAIR": 0.6488225817991896, "ZYPREXA": 1.7501916987708064, "null": 1.42223563803764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5601.json
index f89d2098ccb..07c3be30ce0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5601.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5601.json
@@ -1 +1 @@
-{"ABILIFY": 18.546648288026617, "BUPRENORPHINE": 14.094190526716243, "CYMBALTA": 1.2085101212298497, "DEXAMETHASONE": 6.013483005204564, "KEPPRA": 4.434210431631492, "LANTUS": 1.2450782165582348, "OLANZAPINE": 2.867014376658946, "SUBOXONE": 10.414938221429606, "ZYPREXA": 2.714470591450501, "null": 3.0466004827729294}
\ No newline at end of file
+{"NEXAVAR": 6.587030998065674, "PEGASYS": 5.791091835619644, "SUTENT": 2.509068768949616, "null": 1.5501883510704162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5602.json
index 7c151f502c3..5c8e9ee7cec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5602.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5602.json
@@ -1 +1 @@
-{"ABILIFY": 4.270081839263074, "ATOSIBAN": 108.29782339958244, "BUDESONIDE": 1.619747097284136, "BUPIVACAINE": 9.997270337114802, "BUPRENORPHINE": 3.092174419768444, "CYMBALTA": 1.9819043159693333, "DEXAMETHASONE": 9.666951865279842, "FENTANYL": 4.426249098648336, "INSULATARD": 46.40005896119211, "KEPPRA": 7.408884349136048, "LANTUS": 1.7916862728449614, "LEVEMIR": 6.966338753399174, "LEVETIRACETAM": 3.9778226864152417, "OLANZAPINE": 1.96786965345262, "SUBOXONE": 10.154605265176643, "ZYPREXA": 4.484552222197485, "null": 2.4411862062532084}
\ No newline at end of file
+{"ARAVA": 0.5477417000112046, "ATRIPLA": 0.585924517986437, "BUSULFAN": 8.95288944053289, "DAKLINZA": 35.420927228081126, "EPCLUSA": 24.785368289088403, "EXVIERA": 58.33212065210742, "HARVONI": 12.932037305789096, "NEXAVAR": 13.417094230003466, "OLYSIO": 50.17000056017976, "PEGASYS": 1.4618171686914243, "PEGINTERFERON": 10.755862477019967, "PEGINTRON": 5.677108487319266, "SOVALDI": 16.059846038349804, "null": 1.0328643474444978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5603.json
index bba9dece55e..3d0553a411a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5603.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5603.json
@@ -1 +1 @@
-{"null": 3.9826354958906576}
\ No newline at end of file
+{"ADALIMUMAB": 6.724283580964504, "ANAKINRA": 128.46614996832704, "INFLIXIMAB": 320.4286824637925, "MERCAPTOPURINE": 283.3076266174472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5604.json
index 8b1c4be3a27..2a675c7cf57 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5604.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5604.json
@@ -1 +1 @@
-{"LACOSAMIDE": 96.87803389142852, "SUBOXONE": 20.166080255628472, "null": 4.794057847239342}
\ No newline at end of file
+{"ABACAVIR": 4.62450283413216, "ALEMTUZUMAB": 8.570575819876012, "ANAKINRA": 6.028287199199661, "ASPARAGINASE": 8.363037532467885, "AZATHIOPRINE": 8.038317380536466, "BEDAQUILINE": 15.39518701342432, "BUSILVEX": 56.23841639202787, "CICLOSPORIN": 9.002078447487527, "COMBIVIR": 9.84831592481146, "COMIRNATY": 0.1326854803504075, "CYTARABINE": 4.6136682945475656, "DEXAMETHASONE": 2.692969656644061, "EFAVIRENZ": 11.98462843307787, "EPIVIR": 14.536455110451652, "IBUPROFEN": 2.695171323125412, "JAKAVI": 11.061301136715556, "KALETRA": 4.139109899819189, "LAMIVUDINE": 35.059602296950295, "LEVOFLOXACIN": 2.7674249090925427, "TRUVADA": 0.6051495969278304, "ZYPREXA": 1.838638468091964, "null": 1.0675187593095343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5605.json
index f251bd84b21..c7ec2d97f91 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5605.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5605.json
@@ -1 +1 @@
-{"null": 2.489100169809212}
\ No newline at end of file
+{"ABACAVIR": 0.956593146775178, "ABATACEPT": 0.9535814206519536, "ABIRATERONE": 27.09826907391346, "ACLIDINIUM": 21.478130648738183, "ADALIMUMAB": 1.149390358229617, "AFINITOR": 0.4609361242439131, "ALIMTA": 0.6851400691941403, "AMIKACIN": 5.232923293963265, "AMINOSALICYLIC": 1.3537725914575187, "ANAKINRA": 21.25768806349301, "ANORO": 1.235600017749678, "APTIVUS": 12.607378882023747, "ARAVA": 2.7113411370450806, "ARIPIPRAZOLE": 0.6090584987972842, "ASPARAGINASE": 11.069979152498458, "ATAZANAVIR": 1.4119973590926709, "ATRIPLA": 0.0690586310653875, "AUBAGIO": 0.5260210555806725, "AVANDIA": 0.5485601778603397, "AXITINIB": 14.268333439404133, "AZATHIOPRINE": 4.209778436217082, "BEDAQUILINE": 11.143482604644063, "BEVACIZUMAB": 1.2106158455935818, "BIKTARVY": 0.6738892095381307, "BLINATUMOMAB": 7.607816770877876, "BORTEZOMIB": 1.556228359970414, "BOSULIF": 4.842737385106275, "BRAFTOVI": 1.9536257988043344, "BUDESONIDE": 0.9411579645594876, "BUPRENORPHINE": 0.4745422780886664, "BUSULFAN": 2.4296630495705824, "CABAZITAXEL": 5.911603901428573, "CABOMETYX": 3.3430990204311355, "CAELYX": 3.693891311750168, "CANCIDAS": 2.823826544931943, "CAPECITABINE": 4.857226050939679, "CARMUSTINE": 4.956630564305426, "CASPOFUNGIN": 9.668283011896508, "CELLCEPT": 0.8598938329826379, "CICLOSPORIN": 1.039955045826068, "CIMZIA": 0.4203697236978805, "CLOFARABINE": 7.595775336717903, "CLOPIDOGREL": 0.5577787870186444, "COBIMETINIB": 9.1304284538417, "COMBIVIR": 4.078806108719815, "COMIRNATY": 0.0037913958651088, "COSENTYX": 0.848803825242016, "COTELLIC": 3.9147110418945696, "CRESEMBA": 6.758688786864178, "CYMBALTA": 0.5192026803509797, "CYTARABINE": 1.910675664993407, "DABRAFENIB": 2.916078764798514, "DASATINIB": 2.997220448582712, "DELAMANID": 5.850847030484843, "DELTYBA": 22.390869375384185, "DENOSUMAB": 3.856622085120218, "DEXAMETHASONE": 1.7579072877631954, "DOCETAXEL": 1.4989793851381263, "EFAVIRENZ": 3.151962997086222, "EMTRICITABINE": 7.129990647187765, "ENBREL": 4.823787832979731, "ERLOTINIB": 94.12818719282616, "ESBRIET": 1.081691612944561, "EXJADE": 1.6995205367226716, "FASLODEX": 0.623635993179575, "FILGRASTIM": 4.74742296262051, "FULVESTRANT": 10.440047326227557, "GANCICLOVIR": 1.8122233119303792, "GEFITINIB": 12.271814291520244, "HALAVEN": 1.557446281083742, "IBRANCE": 1.0446354194086398, "IBUPROFEN": 0.5157359960963049, "ICLUSIG": 8.42043415909153, "IMATINIB": 5.313876001116438, "INLYTA": 5.658952619078822, "INVIRASE": 6.083870705208882, "IPILIMUMAB": 18.084465198137583, "IRESSA": 2.3314064927057734, "IRINOTECAN": 1.0090659823185475, "ISENTRESS": 1.264690827698762, "JAKAVI": 2.060573320134922, "KALETRA": 3.965792942378605, "KEPPRA": 0.6406481913695279, "KEYTRUDA": 2.2208908734053985, "KISQALI": 31.71551463656383, "KYPROLIS": 3.050491475426421, "LAMIVUDINE": 7.983379440648861, "LEFLUNOMIDE": 1.6624466317585924, "LEVETIRACETAM": 1.161807364152128, "LEVOFLOXACIN": 2.784420395933539, "LOPINAVIR": 9.612157118370458, "LUMYKRAS": 50.388295503148655, "MEKINIST": 1.7771194038953717, "MERCAPTOPURINE": 11.311071507863923, "METHOTREXATE": 2.083555401659189, "MULTAQ": 2.2396029478194133, "MYCOPHENOLATE": 1.2050036448506751, "NEVIRAPINE": 17.634299746053117, "NEXAVAR": 1.0164242155323575, "NILOTINIB": 12.271001638090668, "NORVIR": 2.034388551964605, "NOXAFIL": 9.44454040464298, "NUBEQA": 8.578679038591302, "OFEV": 3.9754868498428086, "OLANZAPINE": 0.6841768203246501, "ONCASPAR": 14.902398467486284, "OPDIVO": 3.769746093408006, "PANTOPRAZOLE": 0.6654198182159928, "PAZOPANIB": 21.881884249347717, "PEGASYS": 0.1440956473801832, "PEMBROLIZUMAB": 6.908549875594698, "PEMETREXED": 8.437011960379898, "POSACONAZOLE": 8.128528294553155, "PROPRANOLOL": 2.0557096456303454, "REMDESIVIR": 3.85802291327184, "REMICADE": 1.820100419562724, "REYATAZ": 3.263681494975544, "RIBOCICLIB": 42.37642320431733, "RITUXIMAB": 0.6821325248795915, "ROACTEMRA": 0.6342610004648677, "SOLIRIS": 0.573530793830504, "SOMATROPIN": 13.493550296518764, "SORAFENIB": 5.478867204588851, "SOTORASIB": 44.974335675532025, "STELARA": 0.1715895418693868, "STIVARGA": 5.156989869061184, "SUTENT": 1.3919822460045754, "TACROLIMUS": 2.315869496282281, "TAGRISSO": 1.221719716726292, "TAMIFLU": 0.5813511560991768, "TASIGNA": 4.890038492629433, "TEMODAL": 3.1233405925009, "TEMOZOLOMIDE": 3.594665722255572, "THIOTEPA": 15.106087171396371, "TRABECTEDIN": 19.16477250008546, "TRACLEER": 1.334220655892662, "TRISENOX": 7.840642177793671, "TRIUMEQ": 2.230755259211301, "TRUVADA": 0.1494561980349686, "VEKLURY": 5.502463173330285, "VEMURAFENIB": 10.494100004576406, "VFEND": 5.125883905380617, "VIRAMUNE": 17.558247300172678, "VORICONAZOLE": 24.86453081033385, "VOTRIENT": 13.828756504939784, "XALKORI": 10.712764797639675, "XELJANZ": 0.2719218656334253, "XTANDI": 0.3492171137931832, "YERVOY": 6.895680990131609, "YONDELIS": 19.531439013723443, "ZELBORAF": 4.519386010526862, "ZYPREXA": 0.2056557623230862, "null": 0.924361838419778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5606.json
index ed6ec29ab4d..910ac5c64c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5606.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5606.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 28.496191624361337, "null": 2.239033257618621}
\ No newline at end of file
+{"null": 3.181588098901945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5607.json
index 7b94fdfb16d..06fc0735a6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5607.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5607.json
@@ -1 +1 @@
-{"null": 5.5955177896771575}
\ No newline at end of file
+{"AMINOSALICYLIC": 492.1708209018281}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5608.json
index 1f73f344d53..e94e00ba1c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5608.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5608.json
@@ -1 +1 @@
-{"AFINITOR": 2.6849896087158025, "ATEZOLIZUMAB": 20.45436345506358, "AVASTIN": 3.672894875103706, "BEVACIZUMAB": 2.370744962383161, "CELLCEPT": 1.2083971427200375, "CICLOSPORIN": 1.4011103156150992, "CLOPIDOGREL": 1.9165300870793704, "COSENTYX": 1.4951860712264995, "CYTARABINE": 2.602491106837406, "DABRAFENIB": 9.161247639507623, "DEXAMETHASONE": 1.560574005090649, "ELIQUIS": 2.680417327949972, "EXFORGE": 4.554524020868539, "FASLODEX": 1.635521107399281, "FORSTEO": 2.8417359295310503, "HERCEPTIN": 3.380014602364869, "HUMALOG": 1.0912489593104822, "IBRANCE": 1.366910450667586, "JAKAVI": 2.4786002298590435, "KEPPRA": 1.1261169716854744, "KISQALI": 4.562013437372067, "LANTUS": 2.5714638328467165, "LYNPARZA": 5.275852587468256, "LYRICA": 1.2720622890139202, "MEKINIST": 6.164231283551559, "METHOTREXATE": 1.63207318845717, "OPDIVO": 1.887561343073388, "ROACTEMRA": 5.300055248234694, "RUBRACA": 5.61590484322116, "SIMPONI": 4.087961818509343, "STELARA": 1.9540684868080844, "VOTRIENT": 5.259648947893268, "XELJANZ": 2.5127221610796884, "XOLAIR": 1.2751379508910785, "XTANDI": 2.78309094623456, "YERVOY": 5.372987939217346, "ZELBORAF": 32.394735538409606, "null": 1.1558651514672478}
\ No newline at end of file
+{"ARANESP": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5609.json
index 9da77dbf99d..3b38496e85b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5609.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5609.json
@@ -1 +1 @@
-{"ANORO": 2.034132010099591, "ARANESP": 1.6796277087052958, "ARAVA": 1.2468492022964388, "AUBAGIO": 1.11911484176086, "BARACLUDE": 2.8650002289867538, "BIKTARVY": 1.4953613901972729, "BOSULIF": 1.0108312428223285, "BYDUREON": 1.1510539629241308, "CHEMOTHERAPY": 10.777709124109515, "CRIZOTINIB": 7.980252722632817, "DESCOVY": 1.9794135132446724, "DULAGLUTIDE": 2.397209023425353, "ELIQUIS": 5.24066595545308, "EMEND": 1.386161433737718, "ENBREL": 1.8898839305593136, "ERLEADA": 2.164180853164125, "ESBRIET": 1.9138109553102916, "EVENITY": 1.4909852794809386, "EVISTA": 1.1210164364326691, "EXFORGE": 1.7085721144746286, "FAMPYRA": 1.32798266876058, "FASLODEX": 2.3036640622120026, "FILGRASTIM": 1.8439442089264768, "FIRDAPSE": 1.6228986027866543, "FORSTEO": 1.1764806924826294, "HARVONI": 1.3629579402222458, "HIZENTRA": 1.7896683585717437, "HUMALOG": 2.701503050793737, "INCRUSE": 3.883804197451501, "INLYTA": 2.5454735328346323, "INSULIN": 1.333834841863366, "ISENTRESS": 2.0183941028081787, "JANUMET": 1.0574844839849316, "JANUVIA": 2.282813123309375, "JARDIANCE": 3.296049819745635, "LANTUS": 3.128611695573933, "LEVEMIR": 2.4395184968672896, "LIBTAYO": 4.139028660434776, "LYNPARZA": 1.2130974543966615, "LYRICA": 1.552950289581389, "MEKINIST": 1.4156711113379912, "MEPOLIZUMAB": 1.571172736883352, "MIRCERA": 1.596786544543323, "NEULASTA": 2.303041986971433, "NOT": 1.1652819464706885, "NPLATE": 1.0434021845639485, "OCALIVA": 1.2534797184440605, "OFEV": 1.3291249443092183, "OPSUMIT": 1.07496324399825, "PASIREOTIDE": 21.03353439972257, "PLUVICTO": 6.092625850982343, "RAPAMUNE": 4.103570283496334, "REVATIO": 2.3326324008254167, "RINVOQ": 2.233107415963276, "SIMPONI": 2.251512043305429, "SOVALDI": 2.3829166882263846, "STELARA": 1.5757446438091092, "SUTENT": 2.373006754990978, "TORISEL": 4.114377887002928, "TOUJEO": 2.424678179938528, "TOVIAZ": 2.416904902567219, "TRELEGY": 6.841751279746122, "TREMFYA": 1.917228838375948, "TRULICITY": 3.5067715983238488, "VELTASSA": 1.4529844170581514, "VEMLIDY": 4.206086757849832, "VFEND": 2.626276122262664, "VIAGRA": 7.365277405295108, "VICTOZA": 2.016679449408947, "VOTRIENT": 4.357770247904095, "XALKORI": 6.995653352001748, "XELJANZ": 3.900035231921756, "XOLAIR": 1.6317722855399732, "XTANDI": 1.5402588534371842, "ZELBORAF": 1.6280205849121778, "null": 2.5758538298588416}
\ No newline at end of file
+{"ARAVA": 0.138355156895582, "C1": 355.3965786839803, "CINRYZE": 786.3584686317851, "COMIRNATY": 0.006252293529945, "FIRAZYR": 243.83730034031265, "ICATIBANT": 148.55685883911383, "RUCONEST": 384.81613983022, "XOLAIR": 0.4603071148670977, "null": 9.622352391262991}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/561.json
index 67b00dbeedd..4844d723f2f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/561.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/561.json
@@ -1 +1 @@
-{"AFINITOR": 1.480398175946835, "ARANESP": 2.2528687802310547, "AVANDIA": 4.580170668540155, "CLOPIDOGREL": 3.819298092502562, "ELIQUIS": 1.6585946669609697, "ENTRESTO": 9.979374345995724, "EXFORGE": 4.628532070591958, "FORSTEO": 1.6931555247910604, "MIDAZOLAM": 5.580864451503178, "NAGLAZYME": 21.161389535196328, "SPIRONOLACTONE": 11.268573145889905, "XOLAIR": 1.4930608267364336, "ZOMETA": 26.34132372946341, "ZOSTAVAX": 1.6245632960290677, "null": 2.37342960392887}
\ No newline at end of file
+{"COMIRNATY": 5.811394043125332, "SPIKEVAX": 0.7794291658045372, "VAXZEVRIA": 0.4911567792735716, "null": 0.4300530208910899}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5610.json
index bc0d7cd641b..2fdcdf23f18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5610.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5610.json
@@ -1 +1 @@
-{"ABRAXANE": 12.139220611551323, "ADCETRIS": 4.999396475545985, "AFINITOR": 14.766692290719275, "ALECTINIB": 20.35142371057902, "ALIMTA": 10.840530994796836, "ARIPIPRAZOLE": 1.5892755399053802, "AVASTIN": 4.704938817888281, "AVELUMAB": 34.31551260473867, "AXITINIB": 23.478976029793955, "BAVENCIO": 23.7186344047527, "BEVACIZUMAB": 13.513197012277514, "BINIMETINIB": 8.657878374988124, "BLINATUMOMAB": 3.416279302240109, "BLINCYTO": 5.854621454597867, "BORTEZOMIB": 1.5214224364899769, "BOSULIF": 13.477764058775024, "BOSUTINIB": 7.750563083848918, "BRAFTOVI": 41.482383360703295, "BUSULFAN": 1.1152848599630123, "CABOMETYX": 1.4775311342938802, "CAELYX": 6.484491072544475, "CANCIDAS": 3.3264228941321394, "CAPECITABINE": 4.231867734352878, "CAPRELSA": 3.644448726396821, "CASPOFUNGIN": 1.0528242328061272, "CIALIS": 3.9870605567468895, "CLADRIBINE": 2.043606209396206, "CLOFARABINE": 3.410873043513219, "CRIZOTINIB": 13.687230092176735, "CYTARABINE": 2.495175503653735, "DABRAFENIB": 2.573619239728883, "DENOSUMAB": 10.567728316547894, "DEXAMETHASONE": 1.3770830929120683, "DINUTUXIMAB": 20.642783159820247, "DOCETAXEL": 3.9210568211633503, "DOXORUBICIN": 5.393891934457058, "ERBITUX": 3.1683264039448917, "ERIBULIN": 9.50096419372044, "ERLOTINIB": 36.83248526103096, "EVEROLIMUS": 8.151092738862795, "EXJADE": 2.3131460758941658, "FASLODEX": 18.545883051019374, "FILGRASTIM": 4.055131988845357, "FULVESTRANT": 27.262878949959, "GLIVEC": 4.218123562435118, "IBRANCE": 68.26536752826036, "ICLUSIG": 20.95868142075205, "IMATINIB": 4.908439294023079, "INFLIXIMAB": 1.145615915078113, "INLYTA": 46.8356640027241, "IRESSA": 2.999499742324912, "IRINOTECAN": 2.9764128957703253, "LENALIDOMIDE": 4.284263797224767, "LUTATHERA": 6.787175024997808, "LUTETIUM": 6.259368173684158, "LYNPARZA": 1.1434289584446602, "MEKINIST": 1.3341770081057214, "NEULASTA": 1.3602529881691958, "NEXAVAR": 1.441538604571545, "PACLITAXEL": 4.04961524736345, "PALBOCICLIB": 32.93367121164228, "PAZOPANIB": 2.3883253303420777, "PEMETREXED": 5.898010270704583, "RITUXIMAB": 1.2522500653155957, "RUBRACA": 1.2060700226252912, "SORAFENIB": 3.452534897166229, "STIVARGA": 1.2204328194564389, "SUNITINIB": 6.036755141801905, "SUTENT": 34.32529094049958, "TAGRISSO": 2.3573911721813654, "TASIGNA": 1.5419942450111552, "TEMODAL": 3.2329657185116214, "TEMOZOLOMIDE": 10.827016044707758, "TOPOTECAN": 4.272878503168244, "TORISEL": 14.6171425037178, "VOTRIENT": 1.9937658772580011, "XALKORI": 55.10796811966359, "XELODA": 1.6078287987139948, "XOFIGO": 1.6209619760534044, "ZELBORAF": 1.7338759408160316}
\ No newline at end of file
+{"null": 2.4656473380232584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5611.json
index ab96a19da52..731a739207a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5611.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5611.json
@@ -1 +1 @@
-{"AFINITOR": 2.851068581942908, "ASPARAGINASE": 15.05486522354311, "BRAFTOVI": 9.368481757081865, "CICLOSPORIN": 2.972663130440259, "CYTARABINE": 18.0973582551348, "DEXAMETHASONE": 2.741032110547338, "DOCETAXEL": 16.70196546036002, "FASLODEX": 12.951661827650351, "GLIVEC": 89.01957280268876, "IBRANCE": 15.039361850301924, "IMATINIB": 30.84256562737216, "SOMATROPIN": 93.530186464796, "SUTENT": 4.997523244286912, "VFEND": 5.898440360400695, "XELJANZ": 1.7623977791095171}
\ No newline at end of file
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5612.json
index beec5dd18bb..f98727b5f2a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5612.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5612.json
@@ -1 +1 @@
-{"CELLCEPT": 9.442541191957403, "CICLOSPORIN": 10.04857319529661, "COSENTYX": 5.27623807433815, "DEXAMETHASONE": 6.592449898519988, "ENBREL": 9.489136364530047, "JAKAVI": 15.647972769752108, "ZOSTAVAX": 5.879093831947936}
\ No newline at end of file
+{"null": 0.6150315419721749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5613.json
index e1cf0730405..9241be38556 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5613.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5613.json
@@ -1 +1 @@
-{"BEOVU": 73.56496946099988, "ELIQUIS": 4.136404561931448, "EYLEA": 129.7050682507325, "HUMALOG": 3.593824546640325}
\ No newline at end of file
+{"null": 1.4285586325439394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5614.json
index 1ad9d5b1151..4b29371c302 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5614.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5614.json
@@ -1 +1 @@
-{"AIMOVIG": 448.1284763804093, "ERENUMAB": 1602.3203926596684}
\ No newline at end of file
+{"COSENTYX": 32.80857180243192, "null": 1.0738417992000802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5615.json
index 6dd2aaa4354..7dab0060542 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5615.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5615.json
@@ -1 +1 @@
-{"ACLIDINIUM": 38.63190251255492, "APIXABAN": 153.57676362043054, "ATRIPLA": 3.198458489711401, "CELLCEPT": 3.7230717587577207, "CICLOSPORIN": 12.490699521236138, "ELIQUIS": 4.948545414892426, "INLYTA": 24.85979703431633, "JARDIANCE": 2.2052717099337267, "LANTUS": 1.423616690978441, "MYCOPHENOLATE": 16.403682988713747, "SUTENT": 2.84234231184438, "TRUVADA": 1.143361622443084, "VOTRIENT": 8.576910030566427}
\ No newline at end of file
+{"SOMATROPIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5616.json
index 3f62f2e0ec3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5616.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5616.json
@@ -1 +1 @@
-{"AFINITOR": 52.05237856534719}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5617.json
index 13e16d9cac4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5617.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5617.json
@@ -1 +1 @@
-{"ABACAVIR": 1.8945187359821, "ALIMTA": 9.359551566284056, "AMINOSALICYLIC": 5.984178775828358, "AXITINIB": 17.292789469821198, "BENLYSTA": 9.944140421621668, "CICLOSPORIN": 1.5382678016013838, "CLOPIDOGREL": 1.1913756708241898, "HEMLIBRA": 22.588099575935384, "INLYTA": 3.373467730099228, "IPILIMUMAB": 23.81096487403195, "JARDIANCE": 2.4302467603621647, "KEYTRUDA": 33.22766256792849, "OPDIVO": 13.70680988880464, "PEGINTRON": 1.1849726548390116, "PEMBROLIZUMAB": 31.09587608715112, "SUTENT": 1.030060944778609, "TRUVADA": 1.061277287807371}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5618.json
index 9cc187b2e6b..35b177b772d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5618.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5618.json
@@ -1 +1 @@
-{"null": 2.643496268847826}
\ No newline at end of file
+{"ABATACEPT": 0.5122637659206197, "AFINITOR": 0.8844514932016144, "ARAVA": 0.4440026994320074, "AVANDIA": 0.91268074824695, "BENLYSTA": 1.2918547215842282, "BOSULIF": 4.969237201429277, "BRAFTOVI": 2.599225140507091, "BYDUREON": 2.9347360955269863, "BYETTA": 1.989503533441897, "CIMZIA": 2.6087709966668733, "CLOPIDOGREL": 2.158598131741599, "COMIRNATY": 0.0469359660998446, "COSENTYX": 1.6290904991873856, "ELIQUIS": 3.567343029636687, "ENBREL": 1.2235271962479457, "ENTYVIO": 1.406370413878091, "ESBRIET": 2.7964688782164453, "FENTANYL": 0.7721163312902605, "FORSTEO": 1.9036140161943584, "HUMALOG": 2.628828722438105, "HUMIRA": 1.705102543943808, "IBRANCE": 1.690684773587665, "IBUPROFEN": 1.210008823379188, "INLYTA": 2.3519276551861603, "INSULIN": 1.2700403739475097, "ISENTRESS": 6.798062491312155, "JAKAVI": 1.317474112446444, "JANUMET": 1.998061307154671, "JANUVIA": 1.6654573192576545, "JARDIANCE": 0.5183941284715194, "LANTUS": 1.1577158274924353, "LYRICA": 5.406122981796719, "METHOTREXATE": 2.0291406276478794, "NAGLAZYME": 8.039563023613974, "NUCALA": 1.635494858921446, "OPSUMIT": 1.5132550903388633, "PEGASYS": 0.3544954456023342, "PLAVIX": 1.62550444733406, "RAPAMUNE": 15.523409771896915, "RUBRACA": 6.633738957093603, "SIMPONI": 5.854400237779444, "SPIKEVAX": 0.0366874803673145, "STELARA": 4.7421378966747385, "SUBOXONE": 1.34440203000045, "SUTENT": 2.339949888328551, "SYNAGIS": 6.27137578201339, "TOZINAMERAN": 0.1335349666926285, "TREMFYA": 4.089177018644167, "TRUVADA": 0.2973050248738558, "VAXZEVRIA": 0.0540539319249687, "VIAGRA": 10.39443850190733, "XELJANZ": 5.032247517570047, "XOLAIR": 1.1339235182182972, "XTANDI": 0.7234676987487914, "ZOSTAVAX": 3.438002817317248, "ZYPREXA": 0.7279702880414454, "null": 1.428532700124878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5619.json
index 6105c213093..f66868290a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5619.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5619.json
@@ -1 +1 @@
-{"null": 1.5111904302906702}
\ No newline at end of file
+{"null": 2.6454992938449817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/562.json
index 6e6be3b1fba..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/562.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/562.json
@@ -1 +1 @@
-{"AVANDIA": 18.602610553937968, "ELIQUIS": 7.422517329871476, "JARDIANCE": 6.087314031052674, "LANTUS": 3.091085838662212, "null": 1.1596605310689032}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5620.json
index 9544aa94f15..ace0291cabf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5620.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5620.json
@@ -1 +1 @@
-{"MIMPARA": 80.32732908656111, "null": 2.5658516979654964}
\ No newline at end of file
+{"JARDIANCE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5621.json
index aeb4262e266..ef98228caa3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5621.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5621.json
@@ -1 +1 @@
-{"ATRIPLA": 13.785214180238956, "SUTENT": 1.3486355129495975, "TRUVADA": 8.653046718866833}
\ No newline at end of file
+{"null": 3.051504922969584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5622.json
index ea392fa55a3..e5d79f3c2d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5622.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5622.json
@@ -1 +1 @@
-{"ALIMTA": 5.255493209810065, "ARIPIPRAZOLE": 6.075008804696153, "KALETRA": 5.5308123837868814, "MIDAZOLAM": 7.828645544382011, "OLANZAPINE": 4.34623811162273, "TENOFOVIR": 40.97437493593878, "TRUVADA": 1.3075151386068549, "VIREAD": 21.26200462109204, "ZYPREXA": 3.201542183250081, "null": 5.802790186340983}
\ No newline at end of file
+{"COMIRNATY": 0.350735027041586, "null": 0.8080369381263133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5623.json
index 867922caba1..3ff98ece330 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5623.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5623.json
@@ -1 +1 @@
-{"CONTRAST": 262.02365246068035, "OPTIMARK": 639.5132296893016, "null": 2.309298947705535}
\ No newline at end of file
+{"BYETTA": 13.749405786923012, "CIMZIA": 3.8871431123845, "ELIQUIS": 1.530711483352036, "JANUMET": 14.617803265813818, "JANUVIA": 10.707654272441452, "LANTUS": 4.789334890544276, "OPSUMIT": 6.400596211561336, "PLAVIX": 2.775467866205173, "TRELEGY": 14.3759811462674, "VOTRIENT": 5.59520254407644, "ZOSTAVAX": 6.872774239388944, "null": 1.4373624174504966}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5624.json
index 7f36646ee8b..c1ed743becd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5624.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5624.json
@@ -1 +1 @@
-{"ABATACEPT": 1.0187885758342794, "AERIUS": 1.4992723068241471, "AIMOVIG": 2.401879705200065, "APROVEL": 1.2065825902093597, "ARAVA": 2.431805185606731, "ATAZANAVIR": 7.957820034645501, "ATRIPLA": 3.3988420190678585, "AUBAGIO": 2.6480799065970544, "BELIMUMAB": 21.24616349238205, "BENLYSTA": 3.1132338764932683, "BIKTARVY": 1.1699649454771814, "BOSULIF": 1.0328666500199202, "BOTULINUM": 36.43819102619504, "BRAFTOVI": 1.1264489389929893, "BRIVARACETAM": 2.760119299145742, "BYDUREON": 2.8362291717622337, "BYETTA": 4.563248896987959, "CIALIS": 2.44809137021632, "CIMZIA": 1.7509057480228636, "COMBIVIR": 2.056012805956021, "COSENTYX": 1.703762386591983, "CRIXIVAN": 108.00935272651444, "DARUNAVIR": 1.9518903647363997, "ELIQUIS": 1.8994011623721248, "EMPAGLIFLOZIN": 2.218609141326887, "EMTRIVA": 5.844605947168194, "ENBREL": 1.421770611707885, "EPIVIR": 2.301547451766021, "ESBRIET": 2.4740732542418216, "ESOMEPRAZOLE": 1.8062011080962104, "EVISTA": 1.113576182754841, "EXJADE": 2.822571011053649, "FAMPYRA": 3.179608486618043, "FEBUXOSTAT": 3.474103664860489, "FIRDAPSE": 3.365137644866734, "FORSTEO": 4.077386729404583, "FORXIGA": 1.526512758541134, "GALAFOLD": 4.086792359180077, "HEMLIBRA": 4.4243755029452805, "HEPSERA": 1.6664182183102652, "HIZENTRA": 4.9939794894243255, "HUMALOG": 1.6060790814343668, "HUMIRA": 2.129548316573213, "HYDROCORTISONE": 1.6214341748719765, "IBRANCE": 1.427569518876309, "INDINAVIR": 6.733526716356552, "ISENTRESS": 2.047924234110237, "JANUMET": 5.330073768713016, "JANUVIA": 4.021054637924353, "JARDIANCE": 2.352933059557922, "KIVEXA": 13.422247823597411, "LACOSAMIDE": 1.243080651398048, "LANTUS": 1.1062830879737653, "MIMPARA": 2.402138534431345, "NORVIR": 24.02392613476737, "ORKAMBI": 1.958266648509084, "OZEMPIC": 6.057813465282492, "PEGASYS": 1.0899648363642491, "PROPRANOLOL": 4.073491528838657, "REMICADE": 1.7036770100269276, "REYATAZ": 95.4946524093281, "RINVOQ": 1.1708091557525595, "RUBRACA": 1.186936722056348, "RUCONEST": 8.54046866738051, "SAXENDA": 2.642365666476556, "SIMPONI": 2.5735826667052235, "SOLIRIS": 1.3351225672803193, "SPINRAZA": 5.845623521259975, "SPRYCEL": 1.0701703328860717, "STELARA": 2.9541414888518185, "STRIBILD": 3.5586223456193964, "TERIPARATIDE": 6.1441501362115165, "TOBRAMYCIN": 2.809823942435975, "TOVIAZ": 1.3871656044901313, "TREMFYA": 4.388197486484241, "TRULICITY": 1.859048716033461, "TRUVADA": 2.6810816813972003, "VELTASSA": 1.5562284194356324, "VIAGRA": 1.004323983619808, "VICTOZA": 3.028214169668568, "VIMPAT": 1.2823551883728042, "VIREAD": 4.13942258032391, "XARELTO": 1.160386062177979, "XELJANZ": 3.671263112618825, "XYREM": 3.2683663559732485, "ZOSTAVAX": 2.32892741875493, "null": 1.0179142713355107}
\ No newline at end of file
+{"FORSTEO": 75.74112674475187}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5625.json
index 49c60de16da..e560ceb56d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5625.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5625.json
@@ -1 +1 @@
-{"APIXABAN": 12.189822269918857, "ATRIPLA": 41.3887994361458, "AVANDIA": 1.35829056998834, "BASILIXIMAB": 3.632196255333132, "BYETTA": 1.2287746699953, "CELLCEPT": 1.206225296813504, "CICLOSPORIN": 2.52099223713054, "HARVONI": 1.4394821460589975, "HEPSERA": 2.702581694389534, "HUMALOG": 1.012216709542998, "JANUMET": 1.658699040494049, "JANUVIA": 1.1425655259706191, "KALETRA": 1.951619903407564, "RASILEZ": 4.016217036440081, "STRIBILD": 14.935658524312323, "TIVICAY": 3.4347291586537425, "TRESIBA": 4.671340145678388, "TRUVADA": 29.879319102877165, "VIREAD": 12.039688814163268}
\ No newline at end of file
+{"null": 0.5033462095138237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5626.json
index 7459de0a236..0653010d315 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5626.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5626.json
@@ -1 +1 @@
-{"ABACAVIR": 2.357228084229724, "ALEMTUZUMAB": 2.191080728615165, "ALIMTA": 8.349366848945547, "AMIKACIN": 18.60198113024841, "ATAZANAVIR": 6.158190605585218, "AZATHIOPRINE": 4.340298309892899, "BASILIXIMAB": 25.10255011739549, "BIKTARVY": 1.923533078826721, "BUSULFAN": 3.2751340617532256, "CANCIDAS": 3.8669372898050254, "CARMUSTINE": 4.777767750232702, "CASPOFUNGIN": 10.695950586667625, "CELLCEPT": 5.056530041436114, "CICLOSPORIN": 29.705721354069723, "CIDOFOVIR": 105.4011116265018, "CUBICIN": 2.8606416350262838, "CYTARABINE": 1.9660531451149528, "DARUNAVIR": 6.768534060700462, "DELAMANID": 4.955711867891541, "DEXAMETHASONE": 1.451377633900454, "DOCETAXEL": 1.2989030538855284, "DOLUTEGRAVIR": 122.68740612527888, "DULOXETINE": 1.650141489789291, "EFAVIRENZ": 10.862407909727676, "EMTRICITABINE": 50.58966648649003, "EXJADE": 1.3475691155895375, "GANCICLOVIR": 17.35222385259939, "HEPSERA": 6.925310611766496, "IPILIMUMAB": 1.6919788221840868, "KALETRA": 2.819130014787876, "KEYTRUDA": 1.888972287420924, "LAMIVUDINE": 4.099949308267737, "LEVOFLOXACIN": 1.0861739299900728, "LOPINAVIR": 8.660594485151726, "LUTETIUM": 17.83469840638457, "MANNITOL": 19.14072067562964, "METHOTREXATE": 2.1384798335530584, "MYCOPHENOLATE": 6.677698022101296, "NORVIR": 5.664561806643916, "OPDIVO": 1.3086653210799828, "PEMBROLIZUMAB": 4.4615282099775095, "PEMETREXED": 17.20789078806694, "POSACONAZOLE": 7.330339632259821, "STRIBILD": 16.302223077865932, "TACROLIMUS": 26.15257354673421, "TENOFOVIR": 36.3441495212082, "TOBRAMYCIN": 15.63470794955351, "TRUVADA": 1.6775561702357298, "VIREAD": 16.632416206986555, "VORICONAZOLE": 3.982611378022996, "null": 1.6232523243260637}
\ No newline at end of file
+{"COMIRNATY": 1.478268394746601, "ZOSTAVAX": 14.270573918246988, "null": 0.2429649580431189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5627.json
index ae19d0d0889..98095c3095d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5627.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5627.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 16.353003377355375, "null": 1.711279905869139}
\ No newline at end of file
+{"null": 0.499960377561748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5628.json
index 54f153ba0db..0909bf3fc2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5628.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5628.json
@@ -1 +1 @@
-{"ENBREL": 25.874465543965314}
\ No newline at end of file
+{"COMIRNATY": 1.291744881650998, "ENBREL": 3.0600379710161505, "RINVOQ": 35.041685281600294, "SHINGRIX": 17.44806349894638, "SPIKEVAX": 0.9282742015136818, "STELARA": 2.382103485263267, "TOZINAMERAN": 0.7459360326850042, "VAXZEVRIA": 0.6137246905556073, "XELJANZ": 5.47635488976758, "ZOSTAVAX": 13.00684164265436, "null": 0.3828050907033208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5629.json
index b11a1105f85..67283834090 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5629.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5629.json
@@ -1 +1 @@
-{"AFINITOR": 1.2220822475784794, "ALIMTA": 2.9074035701178365, "AVASTIN": 6.427338098305752, "BENLYSTA": 1.002247163465768, "BETAFERON": 4.276446191708813, "BEVACIZUMAB": 6.04845066741208, "CABOMETYX": 5.8287386631001405, "CELLCEPT": 5.160972643255575, "CICLOSPORIN": 15.74217162384833, "CYRAMZA": 54.95641009513694, "ENTYVIO": 1.353166032893347, "EXFORGE": 1.3641810097621074, "GANCICLOVIR": 3.5443542776729555, "HARVONI": 1.9622617031569856, "HUMAN": 2.5153676693698848, "INLYTA": 4.631625972329708, "INTRONA": 6.62360406406957, "KEYTRUDA": 3.1504359303777854, "LAMIVUDINE": 5.450446214539015, "LENVIMA": 15.119008861741564, "MYCOPHENOLATE": 7.424659521508784, "NEXAVAR": 7.691775605357985, "OFEV": 2.398954613152664, "OMALIZUMAB": 1.3600186706977386, "OPDIVO": 1.2011143308942198, "PAZOPANIB": 6.527876194109605, "PEGASYS": 2.2435592816047065, "PEGINTERFERON": 1.6849573592441076, "PEMBROLIZUMAB": 1.707585040329508, "RAPAMUNE": 6.088105424083695, "RIBAVIRIN": 1.7171494396092837, "SIMPONI": 1.7031047285246397, "SOLIRIS": 1.3128828241411457, "SPRYCEL": 4.129193005343136, "STIVARGA": 3.939537064570632, "SUNITINIB": 23.75094271928633, "SUTENT": 8.499525200018242, "TAMIFLU": 1.0264362579230293, "TASIGNA": 1.1257357078791976, "VIREAD": 3.0242179030742102, "VOTRIENT": 4.746626224643749}
\ No newline at end of file
+{"ALEMTUZUMAB": 49.48214126928027, "ARIPIPRAZOLE": 5.092487444046704, "ASPARAGINASE": 4.361995427065136, "ATAZANAVIR": 9.302641643753446, "AZATHIOPRINE": 6.361123036667845, "BUSULFAN": 15.237605784555637, "CELLCEPT": 3.029805218321766, "CICLOSPORIN": 3.9014357749586535, "COMIRNATY": 1.437003739316201, "COSENTYX": 1.2989084446545722, "CYTARABINE": 5.380678817899063, "DEXAMETHASONE": 1.045445817768581, "GARDASIL": 1.0402454925401068, "HUMALOG": 3.045299912521568, "ISENTRESS": 6.222884485707275, "MAVENCLAD": 13.844738833364188, "METHOTREXATE": 3.793329399807715, "MODERNA": 1.694000548671998, "PEGINTRON": 1.8573947591484203, "RINVOQ": 16.660184351716676, "RITUXIMAB": 2.6521205666547587, "RUXOLITINIB": 9.455190357220689, "SHINGRIX": 8.85112909970152, "SIMPONI": 0.739052464151063, "SOLIRIS": 1.548199848771616, "SPIKEVAX": 0.8277682086614035, "STELARA": 0.9078196676861776, "TOZINAMERAN": 0.408765524981795, "VAXZEVRIA": 0.5629788210804321, "XELJANZ": 1.1268741320168778, "XOLAIR": 1.165581215856921, "ZOSTAVAX": 8.11575478613205, "null": 0.4191848724851968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/563.json
index 892144dc827..2fc59dc7759 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/563.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/563.json
@@ -1 +1 @@
-{"ZOSTAVAX": 9.83081577944338, "null": 1.596671536386941}
\ No newline at end of file
+{"COMIRNATY": 1.7342505107612949, "SPIKEVAX": 0.4518288554840898, "VAXZEVRIA": 0.5097133932201888, "null": 2.145810639247743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5630.json
index df051c29d9c..b17078bb2c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5630.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5630.json
@@ -1 +1 @@
-{"CICLOSPORIN": 280.08380551729664}
\ No newline at end of file
+{"RELVAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5631.json
index f125e0d314a..a4999ba9f89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5631.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5631.json
@@ -1 +1 @@
-{"ENBREL": 44.275926947221066, "null": 1.067366365207655}
\ No newline at end of file
+{"COMIRNATY": 0.4688062371972107, "DEXAMETHASONE": 33.29066110657138, "null": 0.3763244122588169}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5632.json
index 83e26d63f55..2264aa87b78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5632.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5632.json
@@ -1 +1 @@
-{"AUBAGIO": 2.472623960927029, "BUDESONIDE": 1.0597703549238393, "CANNABIDIOL": 22.40117854522213, "CIMZIA": 1.2239389623719783, "CYMBALTA": 1.2138982400360288, "ELIQUIS": 1.0273742625012965, "ENBREL": 1.6379441559690613, "FORSTEO": 2.4100372250050723, "HUMALOG": 3.869279632810292, "HUMIRA": 5.211818867345266, "HYDROCORTISONE": 20.805389158093075, "IBRANCE": 1.5304036222083142, "IBUPROFEN": 7.590653751468527, "JARDIANCE": 1.363423110474054, "LANTUS": 1.4972798229972604, "LYRICA": 4.999192310263951, "MEPOLIZUMAB": 4.549972307157433, "OCEAN": 283.4974384664607, "OMALIZUMAB": 6.084195779428255, "RINVOQ": 3.7905352177558, "SIMPONI": 2.410458561107661, "SUBOXONE": 4.503181881133476, "TOZINAMERAN": 1.610474788036297, "VIAGRA": 7.345848160742834, "XELJANZ": 7.295610284416162, "XTANDI": 1.902470670397213, "ZOSTAVAX": 2.610670728636749}
\ No newline at end of file
+{"TRASTUZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5633.json
index 62849e38b86..7d7aefdb040 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5633.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5633.json
@@ -1 +1 @@
-{"null": 1.1849644289398389}
\ No newline at end of file
+{"HUMIRA": 355.07134329475025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5634.json
index 85b83051809..6e403abc94d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5634.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5634.json
@@ -1 +1 @@
-{"null": 1.3613415485503635}
\ No newline at end of file
+{"COMIRNATY": 2.8832543039241787, "SPIKEVAX": 1.6111658173394665, "VAXZEVRIA": 0.723274455355814, "null": 0.1582029850494111}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5635.json
index 43187fb0a22..330a056bcdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5635.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5635.json
@@ -1 +1 @@
-{"ABACAVIR": 1.1382629970787523, "ABATACEPT": 1.4763771933489132, "ARAVA": 3.5035650715671265, "AVANDIA": 1.4011359187360723, "BEVACIZUMAB": 5.370427662085597, "COMBIVIR": 2.093061644280116, "FASLODEX": 2.9801828876678647, "HUMALOG": 3.1429455018269894, "IBRANCE": 2.6269853037258817, "INSULIN": 1.014344994038693, "LANTUS": 1.7534803606757, "LEVEMIR": 1.7659482272740723, "LEVOFLOXACIN": 1.1153490496692742, "LYRICA": 8.55941714440394, "MEPOLIZUMAB": 1.1621475861177826, "MIDAZOLAM": 2.6035976497468103, "PLAVIX": 1.1258998495843766, "SHINGRIX": 3.661290444507724, "SUBOXONE": 2.3013412585414783, "TOZINAMERAN": 2.569295941281553, "VIAGRA": 4.288157946079251, "XELJANZ": 1.8374157488354552, "ZOSTAVAX": 11.338229505166307, "null": 1.180358122498854}
\ No newline at end of file
+{"TAGRISSO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5636.json
index e2998e36555..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5636.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5636.json
@@ -1 +1 @@
-{"null": 1.609848241428752}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5637.json
index c3d9becbc4e..efc869f2bad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5637.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5637.json
@@ -1 +1 @@
-{"null": 1.1464456165419163}
\ No newline at end of file
+{"null": 0.6564663807179607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5638.json
index 0259a187be6..a4c4601659d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5638.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5638.json
@@ -1 +1 @@
-{"APIDRA": 1.0905358239843346, "ASPARAGINASE": 1.5065960466921664, "ATEZOLIZUMAB": 9.8152565456443, "BENLYSTA": 1.0582075890807454, "BEVACIZUMAB": 3.117851772203976, "BIKTARVY": 7.323679230407762, "BUPRENORPHINE": 1.1172369882970483, "CELSENTRI": 15.924331632167846, "CICLOSPORIN": 1.0772846552714752, "COMBIVIR": 1.1802652792836386, "COSENTYX": 2.24123722361904, "CYTARABINE": 2.6596998601594053, "DEXAMETHASONE": 1.0794185266816, "EFAVIRENZ": 2.9949014201624644, "ENOXAPARIN": 1.5888873286153695, "EPIVIR": 4.450318610071912, "FAMPYRA": 1.1024073503309364, "FASENRA": 1.2495350561046812, "FENTANYL": 1.9138394928152465, "FILGRASTIM": 2.3308717899712668, "GARDASIL": 2.8370247140589893, "HARVONI": 1.0280276422241688, "INTELENCE": 17.010059857792, "ISENTRESS": 1.4688222660935557, "KALETRA": 1.0868063838860764, "KYMRIAH": 6.08858583728322, "LEVOFLOXACIN": 2.07662505610088, "LYRICA": 1.364996368480995, "MIDAZOLAM": 2.526842079333527, "NOT": 4.132229480147723, "OLANZAPINE": 1.206814334380798, "OXYBUTYNIN": 5.71662493253048, "PEGINTRON": 1.095236291406693, "PREGABALIN": 2.526718538532097, "RASBURICASE": 19.946357158042847, "SOLIRIS": 1.5405321907666325, "SPINRAZA": 1.193319235299806, "THIOTEPA": 14.202169728341207, "TIVICAY": 4.602720773527096, "TOVIAZ": 1.5813697823417938, "TOZINAMERAN": 1.007289338943086, "TRIENTINE": 75.2965792521512, "TRIUMEQ": 2.588420505184052, "TWINRIX": 2.3121264873124527, "VAXZEVRIA": 1.0196669343497395, "VFEND": 1.3326792665817937, "VORICONAZOLE": 5.956735772289727, "YESCARTA": 3.036023505601178, "ZOSTAVAX": 2.7175111887767254, "null": 1.4241208359825688}
\ No newline at end of file
+{"AIMOVIG": 1.00603840754239, "ALEMTUZUMAB": 2.437823389196057, "ARAVA": 0.2123008220292678, "AUBAGIO": 1.5953555546096547, "BENLYSTA": 3.657840266375231, "BUSULFAN": 2.669803928079617, "CELLCEPT": 4.867830116271139, "CICLOSPORIN": 3.6365066774368464, "CIMZIA": 1.993989066678852, "COMBIVIR": 3.960215327357408, "COMIRNATY": 1.6529038715175366, "COSENTYX": 1.89832923955258, "CYMBALTA": 1.002443659069115, "CYTARABINE": 1.3617929308156218, "EPIVIR": 6.384761337558008, "FENTANYL": 0.7559676575186703, "FORSTEO": 0.9902408220465244, "JAKAVI": 4.386958954300336, "KALETRA": 2.807230150837427, "METHOTREXATE": 2.646830550476622, "PEGASYS": 0.9257167502704632, "PEGINTERFERON": 1.7154036413962264, "RINVOQ": 20.772925021600937, "ROACTEMRA": 3.0785929945535906, "SHINGRIX": 7.404053840389325, "SIMPONI": 6.5030429676225, "SPIKEVAX": 1.1668935990422828, "STELARA": 3.127823241674897, "SUTENT": 0.7316935236491974, "TOZINAMERAN": 0.3043821946706319, "TREMFYA": 4.534687074987334, "VAXZEVRIA": 0.671499604614309, "XELJANZ": 2.489740750606883, "XOLAIR": 0.9675146596354892, "ZOSTAVAX": 3.327170132087328, "null": 0.4096892362820492}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5639.json
index ddd1af291fd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5639.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5639.json
@@ -1 +1 @@
-{"ABILIFY": 1.1593604562889408, "ACTOS": 1.5544514546303687, "AERIUS": 2.322218633761326, "APIDRA": 4.356519650079207, "BENLYSTA": 2.2382170578450133, "BIKTARVY": 1.7782291136486008, "BRINTELLIX": 4.313540760896908, "BRIVIACT": 2.0987424382245714, "BYDUREON": 1.1012916398040118, "CHAMPIX": 5.365025643749227, "CIRCADIN": 2.648308451035515, "COMTAN": 1.8454866263038776, "CYMBALTA": 2.1454673488969136, "DAKLINZA": 4.355902856228382, "EXFORGE": 2.931795259301165, "FAMPYRA": 1.0467614179264646, "FIRDAPSE": 2.1004215225844822, "FORSTEO": 1.8028356673502777, "FYCOMPA": 2.674890638713748, "GALVUS": 1.5893619751317527, "GLYCOPYRRONIUM": 3.25780036988099, "IBRANCE": 1.6652004632441375, "INCRUSE": 1.193275122876397, "INTRONA": 1.5028687770410207, "KAFTRIO": 1.3349236309535495, "KEPPRA": 2.534013444914005, "LANTUS": 3.1893565617729305, "LATUDA": 2.082205177468173, "LEVETIRACETAM": 1.3334744834673138, "LYRICA": 2.462824445142416, "MELATONIN": 1.1375310176511737, "NUCALA": 1.08979273913549, "OCALIVA": 2.500585402662928, "OMALIZUMAB": 1.403419417092289, "PEGASYS": 2.1920055466226738, "PEGINTERFERON": 1.3347058570450403, "PEGINTRON": 2.281610054257478, "PREGABALIN": 1.1520578580632383, "PROLIA": 4.0959464766758495, "RASILEZ": 1.574887218254751, "RELVAR": 1.4895573881743642, "SAXENDA": 1.3270354966013844, "SILDENAFIL": 1.1395829595473022, "STALEVO": 3.309137962557001, "SUBOXONE": 1.3530461811986867, "SYCREST": 2.9747076280888964, "TIVICAY": 2.4960177052602344, "TOUJEO": 3.000444619679882, "TOVIAZ": 1.2904556608729676, "TOZINAMERAN": 1.117567407757342, "TRELEGY": 1.66637768684479, "VALSARTAN": 1.3516141941643236, "VIMPAT": 1.2802661154871977, "XYREM": 5.17106940957871, "ZYPREXA": 1.7222042976254728, "null": 2.526693448266528}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/564.json
index 4581f5c8c1b..1eeb6bdf30a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/564.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/564.json
@@ -1 +1 @@
-{"ALENDRONATE": 884.2587082422037, "APIXABAN": 88.8763762670528, "AVANDIA": 10.39883154122372, "CLOPIDOGREL": 4.821591301420276, "DULOXETINE": 12.79745250913199, "ELIQUIS": 6.475274421695546, "FORSTEO": 3.88821789437354, "SILDENAFIL": 18.686773899753693}
\ No newline at end of file
+{"BRIDION": 31.643062098232445, "BUPIVACAINE": 23.08295884347801, "FENTANYL": 17.949859931588605, "MIDAZOLAM": 17.36179230822008, "SUFENTANIL": 65.0873203784674, "null": 8.114010023518599}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5640.json
index 6d40675bf9d..81618591d92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5640.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5640.json
@@ -1 +1 @@
-{"COMBIVIR": 54.92696561304764, "DESCOVY": 65.42523578250851, "null": 9.12527190069441}
\ No newline at end of file
+{"ABACAVIR": 0.1479603910031152, "ABATACEPT": 0.1872250746861443, "ADALIMUMAB": 0.0430242386401329, "AFINITOR": 0.2942934100918539, "AIMOVIG": 0.2616571935306493, "ALDARA": 0.8105916659423965, "ALEMTUZUMAB": 1.5381108176590406, "ALIMTA": 0.2187604380418092, "ANAKINRA": 2.8534408136349603, "APIXABAN": 0.1611792681149673, "ARANESP": 0.1971019486657192, "ARAVA": 0.3813829918420032, "ARIPIPRAZOLE": 0.1315825824765432, "ASPARAGINASE": 0.1932604424018802, "ATAZANAVIR": 0.376270565475655, "ATRIPLA": 0.0101157165663907, "AUBAGIO": 0.5812798123443756, "AVAMYS": 0.4115078453688051, "AVASTIN": 0.1162617063822132, "AZATHIOPRINE": 1.0331701816662735, "BENLYSTA": 1.30960530818724, "BEVACIZUMAB": 0.1407484423075206, "BIKTARVY": 0.2653800054216985, "BORTEZOMIB": 0.8950736314850265, "BRAFTOVI": 0.1520339564466853, "BRIVARACETAM": 0.7091834299172225, "BUDESONIDE": 0.0556519301363364, "BYDUREON": 0.3457613431476848, "BYETTA": 0.1344315997280107, "CABOMETYX": 0.1079282221707172, "CARFILZOMIB": 0.6013995639636239, "CELLCEPT": 1.9989796831384687, "CHAMPIX": 0.0378657779188036, "CICLOSPORIN": 0.5582374596255985, "CIMZIA": 1.3608735351631676, "CLADRIBINE": 1.4484328561209676, "CLOFARABINE": 1.4186153456539452, "CLOPIDOGREL": 0.0389628557070625, "COMIRNATY": 2.2074986992071337, "COSENTYX": 0.827172427999053, "CYMBALTA": 0.2199918120081175, "CYTARABINE": 0.3661403822969228, "DARZALEX": 0.6681614115582235, "DESLORATADINE": 0.6807505295369389, "DEXAMETHASONE": 0.5311470378912109, "DOCETAXEL": 0.2414642716949272, "DULOXETINE": 0.3398232162527123, "DUPIXENT": 0.6785740296701681, "EFAVIRENZ": 0.2777108250289619, "ELASOMERAN": 6.217454033881553, "ELIQUIS": 0.1215571029884146, "ENBREL": 1.678865799197778, "ENTRESTO": 0.0701083929406685, "ENTYVIO": 0.904898301276793, "EPIVIR": 0.7948476833491052, "ERELZI": 1.414406078448727, "ESBRIET": 0.4608964487523623, "ETANERCEPT": 1.7383517465039846, "EVENITY": 0.5315828401719952, "EVISTA": 0.2279060712433577, "EXJADE": 0.3341396214903753, "EYLEA": 0.0988675428107749, "FAMPYRA": 0.6107931088438961, "FASENRA": 1.3543802442008372, "FASLODEX": 0.3562438706439434, "FENTANYL": 0.0614584377769519, "FORSTEO": 0.4997288419190729, "FORXIGA": 0.2836254207385986, "FULVESTRANT": 0.4850628870089274, "GANCICLOVIR": 0.6020593401886841, "GARDASIL": 0.2173545072718598, "GOLIMUMAB": 1.7722088662887352, "HALAVEN": 0.3685185994583592, "HARVONI": 0.2195911202929031, "HIZENTRA": 0.4065245513989884, "HUMALOG": 0.174549501850575, "HUMAN": 0.2568116894735712, "HUMIRA": 0.9168734821068142, "HYDROCORTISONE": 0.4709957950524874, "IBRANCE": 0.3753207336947187, "IBUPROFEN": 0.2533260453682454, "ICLUSIG": 0.1710776905411475, "INCIVO": 0.193103799147263, "INFLIXIMAB": 0.5707782469164004, "INVIRASE": 1.5081249419542748, "IPILIMUMAB": 0.1554076036857636, "IRESSA": 0.3322611478484255, "ISENTRESS": 0.2992457163428033, "JAKAVI": 3.7766626563107946, "JANUMET": 0.1599174712860948, "JANUVIA": 0.183768979197993, "JARDIANCE": 0.0727285460172382, "JEVTANA": 0.3283458962291085, "KALETRA": 0.1215681004213498, "KEPPRA": 0.0502207345732379, "KESIMPTA": 1.2407800114732683, "KEYTRUDA": 0.307945650421397, "KYMRIAH": 0.2185333953445755, "LANTUS": 0.1051694234993874, "LEMTRADA": 1.930592272137364, "LEVEMIR": 0.0921384197021286, "LEVOFLOXACIN": 0.0582605026150256, "LUPKYNIS": 1.3180956857825217, "LYRICA": 0.608858143261972, "MABTHERA": 0.6966553403009248, "MAVENCLAD": 6.662502878490866, "MELPHALAN": 1.168541953486569, "MEPOLIZUMAB": 0.2309903476963352, "MERCK": 17.952416527121674, "METHOTREXATE": 0.9005267302516217, "MICARDIS": 0.2270847147798377, "MMRVAXPRO": 0.1315554697543012, "MODERNA": 1.404092697354772, "MYCOPHENOLATE": 0.6930369634762553, "NEULASTA": 0.1386034944285348, "NEXAVAR": 0.0427415407151103, "NIMENRIX": 0.185085884715093, "NINLARO": 0.9556775094034424, "NOT": 2.548771515691624, "NPLATE": 0.2696438707226631, "NUCALA": 0.9497481149025724, "OCRELIZUMAB": 0.4998184791508299, "OLUMIANT": 6.555151153543076, "OLYSIO": 0.550862230555313, "OMALIZUMAB": 0.5544992167928257, "OPDIVO": 0.1714173152092581, "OPSUMIT": 0.2312506370270105, "OZEMPIC": 1.3734222232834647, "PANTOPRAZOLE": 0.1574467324211428, "PEGASYS": 0.1619056136999191, "PEGINTRON": 0.1173584163855731, "PEMBROLIZUMAB": 0.1136749906886999, "PLAVIX": 0.0423734452313914, "PLEGRIDY": 0.4578730220255129, "PREGABALIN": 0.2399309189976706, "PREVENAR": 0.5524111694006587, "PROLIA": 0.9990980085082172, "QUTENZA": 0.7266050046736899, "RAPAMUNE": 0.676973172790989, "REMICADE": 1.2459886747469746, "REVATIO": 0.2139101094958664, "REVLIMID": 0.6441928207433186, "REYATAZ": 0.6095799655706943, "RIBAVIRIN": 0.1603966934670371, "RINVOQ": 10.132960571407825, "RITUXIMAB": 1.14061211048479, "ROACTEMRA": 2.9803672973066195, "RUBRACA": 0.3276928148733393, "RUXOLITINIB": 1.261866943020305, "SAXENDA": 0.165177898933952, "SHINGRIX": 40.42696419966883, "SILDENAFIL": 0.2241949125769732, "SIMPONI": 1.8117747635319976, "SKYRIZI": 0.7799236997854525, "SOLIRIS": 0.4332121312939772, "SOVALDI": 0.2892894407133797, "SPIKEVAX": 1.2770083550705578, "SPRYCEL": 0.114112842439486, "STELARA": 1.261884915663708, "SUBOXONE": 0.0851288478630538, "SUTENT": 0.1261010512367021, "TAGRISSO": 0.2472976307401617, "TASIGNA": 0.235335640427113, "TEMODAL": 0.6288042111452823, "TOCILIZUMAB": 0.950334023604648, "TOFACITINIB": 3.9688817048490073, "TORISEL": 0.5563930234192425, "TOZINAMERAN": 1.1185453368007283, "TRACLEER": 0.1210286548482962, "TRELEGY": 0.2139166581063568, "TREMFYA": 0.7972386552435967, "TRIUMEQ": 0.4718157556269819, "TRULICITY": 0.1082892302640848, "TWINRIX": 0.4751855088730981, "UPADACITINIB": 8.289182462460916, "VAXZEVRIA": 0.7609777166477802, "VELCADE": 1.523509173774115, "VIAGRA": 0.0691860428135969, "VOTRIENT": 0.1168469725076261, "XALKORI": 0.2056018101821855, "XELJANZ": 3.833068933253675, "XOLAIR": 0.6360126596672934, "XTANDI": 0.2711671420968772, "YERVOY": 0.3265889275376866, "ZOSTAVAX": 50.54994619285371, "ZYPREXA": 0.068317675826549, "null": 0.4286324051808348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5641.json
index d970b7392b4..054fc2effd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5641.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5641.json
@@ -1 +1 @@
-{"AIMOVIG": 1.1189963808425554, "AUBAGIO": 2.1971677395686915, "AZILECT": 7.314318115155658, "BORTEZOMIB": 2.86210752542952, "BUPIVACAINE": 6.505878910478043, "COMIRNATY": 2.7076202161824394, "COVID19": 1.815465864501484, "CYMBALTA": 1.4737317295275916, "DARBEPOETIN": 17.514183820995754, "DESLORATADINE": 2.360310786046996, "DINUTUXIMAB": 14.104996693691866, "FAMPYRA": 2.807592063739979, "FASLODEX": 1.8517178694011247, "FORSTEO": 2.414078231833297, "GARDASIL": 1.760379094098945, "HYDROCORTISONE": 5.3206100426639455, "ILARIS": 26.18203562747009, "KESIMPTA": 1.2013275047184675, "LYRICA": 4.447744116238967, "MELATONIN": 1.7532473083832458, "NOXAFIL": 2.1974396879125173, "QUTENZA": 2.519298233887701, "REVLIMID": 1.2001770826434104, "SHINGRIX": 10.176061067158184, "SPIKEVAX": 1.5459643505247305, "TOZINAMERAN": 2.138028816407344, "TWINRIX": 2.671330428562546, "VAXZEVRIA": 1.7537529344643543, "XYREM": 2.436432241168069, "ZOSTAVAX": 7.063246701746626}
\ No newline at end of file
+{"COMIRNATY": 1.3083720661006188, "SHINGRIX": 36.20414392049136, "SPIKEVAX": 0.6003725637536386, "ZOSTAVAX": 20.229811332101136, "null": 0.1530390274713689}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5642.json
index 6ba03dca975..93c71ab608f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5642.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5642.json
@@ -1 +1 @@
-{"COMIRNATY": 5.649980460817649, "SHINGRIX": 5.856573990103475, "SPIKEVAX": 2.995391023354006, "TOZINAMERAN": 2.087049116050822, "VAXZEVRIA": 1.3818369732237128}
\ No newline at end of file
+{"ALEMTUZUMAB": 23.658932419314095, "CELLCEPT": 19.45674023953803, "CICLOSPORIN": 5.816259775649258, "COMIRNATY": 0.1997317879064414, "RINVOQ": 15.070652717335111, "SHINGRIX": 10.519280370414725, "XELJANZ": 4.145534360985906, "ZOSTAVAX": 83.18999063285824, "null": 0.2442188046702365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5643.json
index 97fa1a826f2..39f99aa1c1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5643.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5643.json
@@ -1 +1 @@
-{"null": 2.8888362465479496}
\ No newline at end of file
+{"COMIRNATY": 0.8717825462304636, "ZOSTAVAX": 41.144972972938405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5644.json
index 67ad55de471..27363f7aefb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5644.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5644.json
@@ -1 +1 @@
-{"ANORO": 304.8002359017744, "APIXABAN": 39.321051932693294, "AZATHIOPRINE": 14.448614041635516, "COMIRNATY": 2.0918669950175723, "SHINGRIX": 4.008085739666925, "TWINRIX": 19.31777602578721, "VAXZEVRIA": 1.0013956136903008, "ZOSTAVAX": 5.400003832179604}
\ No newline at end of file
+{"COMIRNATY": 1.8656298978913624, "SPIKEVAX": 0.5307340823837847, "null": 0.4066753475451627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5645.json
index dc5ea0b9305..87c3ebd9f81 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5645.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5645.json
@@ -1 +1 @@
-{"COMIRNATY": 1.671720354814651}
\ No newline at end of file
+{"CELLCEPT": 23.680256192794133, "COMIRNATY": 0.9898773083899234, "ZOSTAVAX": 12.963884359208231, "null": 0.2977713253129739}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5646.json
index 5b037be040b..5812979a0a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5646.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5646.json
@@ -1 +1 @@
-{"TOPOTECAN": 528.8684434796431, "null": 1.052370515841698}
\ No newline at end of file
+{"COMIRNATY": 1.90380283818111, "SHINGRIX": 32.324991656953955, "SPIKEVAX": 0.8577770659335551, "TOZINAMERAN": 1.9054642606514305, "VAXZEVRIA": 0.4336261118843642, "ZOSTAVAX": 66.95341499750187, "null": 0.2761168093139464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5647.json
index dc95960b108..20bbea9e930 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5647.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5647.json
@@ -1 +1 @@
-{"CANNABIDIOL": 545.5897569526122, "QARZIBA": 2551.4870964439315}
\ No newline at end of file
+{"COMIRNATY": 2.204623656123472, "SHINGRIX": 26.962089273872877, "SPIKEVAX": 1.442347143848026, "TOZINAMERAN": 1.8426326408371885, "VAXZEVRIA": 0.1844632350743572, "ZOSTAVAX": 59.06920646252112, "null": 0.0586185160483266}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5648.json
index 3389559d805..9d6450ca9ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5648.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5648.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2026996934241965}
\ No newline at end of file
+{"COMIRNATY": 0.4279744198844294, "null": 3.387136661598981}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5649.json
index 006efe0e11b..95002a5adb6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5649.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5649.json
@@ -1 +1 @@
-{"null": 1.6048559675751095}
\ No newline at end of file
+{"NORVIR": 182.35772313239215, "null": 1.6822664836665353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/565.json
index 6d55750d5d7..aaa10e3c9c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/565.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/565.json
@@ -1 +1 @@
-{"null": 2.739337169947462}
\ No newline at end of file
+{"FENTANYL": 6.451099949958561, "MIDAZOLAM": 638.727152898888, "SUFENTANIL": 893.9317810214162, "null": 0.9179747699496228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5650.json
index 77f3201df86..1e3253192a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5650.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5650.json
@@ -1 +1 @@
-{"COMIRNATY": 2.978623963247665, "COSENTYX": 3.995171721601437, "GARDASIL": 1.101212217472603, "HEXYON": 101.14428493815488, "INFANRIX": 43.20443839174434, "KEYTRUDA": 1.5576055123469723, "PEGASYS": 1.0927592228447758, "SPIKEVAX": 1.9061853229675985, "STELARA": 1.5216989355320143, "TWINRIX": 11.963244230239397, "ZOSTAVAX": 3.1705791747851166}
\ No newline at end of file
+{"null": 4.195671911955299}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5651.json
index a5652e1e127..0b9e7e66ca3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5651.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5651.json
@@ -1 +1 @@
-{"null": 11.904228559389969}
\ No newline at end of file
+{"ACTOS": 6.220564909652137, "ADENURIC": 5.582588316755717, "ARAVA": 0.2586452209192933, "ATAZANAVIR": 3.606805955286504, "AVAMYS": 6.142335296694983, "BRILIQUE": 1.2485932301281768, "BUDESONIDE": 2.2470960450838016, "BYDUREON": 1.4337658274921825, "BYETTA": 4.68797654007014, "CELLCEPT": 0.7567974474908206, "CIMZIA": 0.552054569773121, "CLOPIDOGREL": 1.3713291940236187, "COMIRNATY": 0.0401111261297919, "COSENTYX": 0.8373384224845875, "CYMBALTA": 0.5288334220988689, "DENOSUMAB": 7.604055509230259, "DEXAMETHASONE": 0.5879878701556507, "ELIQUIS": 1.2874894101925438, "ENBREL": 1.2106370986952444, "ESBRIET": 2.2120338347273583, "EXFORGE": 1.4903924384336174, "FASLODEX": 1.0262456833497269, "FORSTEO": 3.7366287009973895, "GARDASIL": 0.3994130590581008, "HUMALOG": 0.6909426830382843, "HUMIRA": 0.9724296043941304, "IBRANCE": 0.7653055131931116, "IBUPROFEN": 1.3324816128690018, "IRBESARTAN": 2.240430234191863, "JANUMET": 6.072028221539005, "JANUVIA": 6.082942835515455, "KEYTRUDA": 0.2786439556744745, "LANTUS": 0.3396583360198819, "LEVOFLOXACIN": 0.6814229132718457, "LYRICA": 1.1003505084281977, "METHOTREXATE": 2.895170374025387, "OCRELIZUMAB": 1.7594307365654966, "OMALIZUMAB": 1.528423309658489, "PANTOPRAZOLE": 1.4531080461947372, "PEGASYS": 0.5697647282331479, "PEGINTRON": 0.3661634825631289, "PLAVIX": 2.282016149706135, "SEEBRI": 39.99138034595639, "SIMPONI": 0.5267489670010417, "SPIKEVAX": 0.0744178197402192, "SPIRONOLACTONE": 9.260051774443756, "SPRYCEL": 1.0531749402639532, "SUTENT": 0.9206180934561786, "TOZINAMERAN": 0.1067035257197086, "VAXZEVRIA": 0.043081452043923, "XELJANZ": 1.0309591254206896, "XOLAIR": 1.597372685759248, "ZOSTAVAX": 3.0740159254079744, "ZYPREXA": 0.5963934570191821, "null": 3.714955582519947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5652.json
index 2d82389dd84..c553b8f04b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5652.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5652.json
@@ -1 +1 @@
-{"CICLOSPORIN": 13.375418742024529, "JAKAVI": 82.92425922340112, "RINVOQ": 27.869252458487264, "XELJANZ": 5.985781662082982}
\ No newline at end of file
+{"ADCIRCA": 8.123789971034313, "ALIMTA": 5.019894154420486, "AVASTIN": 4.791083889350189, "BEDAQUILINE": 6.972485855067602, "BEVACIZUMAB": 7.78733258193343, "BYDUREON": 1.9018438829836304, "CAPECITABINE": 3.786307735107498, "CLOPIDOGREL": 0.6451576143716236, "COMIRNATY": 0.1500123592666814, "DEXAMETHASONE": 3.0674557365067776, "EMEND": 36.49961914269803, "ENTRESTO": 0.9444089719847244, "FENTANYL": 0.7310122005018274, "GARDASIL": 0.4599344722660962, "IBRANCE": 0.7485206571049586, "IRINOTECAN": 5.816193383212857, "JANUMET": 1.3795910385797117, "KEPPRA": 1.549428121335553, "KEYTRUDA": 0.6494506304135645, "LEVOFLOXACIN": 0.9646925725761252, "MIDAZOLAM": 2.820123927446156, "NEXAVAR": 3.107871733802602, "OPDIVO": 1.8395303689476343, "SAXENDA": 3.8060620152388194, "SPIKEVAX": 0.2111747217892527, "SUTENT": 5.597375106076228, "TACROLIMUS": 7.0034951531256535, "TEDUGLUTIDE": 52.35140991832138, "TOZINAMERAN": 0.3073591161448283, "TRULICITY": 6.6596385647474845, "VAXZEVRIA": 0.1494829117759049, "VFEND": 1.3826012273109505, "VICTOZA": 4.3221924562634975, "VOTRIENT": 1.8543602185095016, "ZYPREXA": 0.6295714188311715, "null": 2.6956339621123195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5653.json
index e3a6e7db294..ac16cd99150 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5653.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5653.json
@@ -1 +1 @@
-{"AFINITOR": 170.68746585727607, "BYETTA": 8.674153217862413, "EVEROLIMUS": 49.35720273574054, "LUTATHERA": 432.6586984026894, "SUTENT": 1.748451867915773}
\ No newline at end of file
+{"ADALIMUMAB": 8.4523436505689, "CELLCEPT": 5.09129931273874, "CIMZIA": 9.398876952570834, "COMIRNATY": 0.4411458578561399, "COSENTYX": 23.23881240494213, "ENTYVIO": 7.238115992178653, "ERTAPENEM": 209.23020093874217, "GARDASIL": 2.876777436521344, "HUMIRA": 46.584990412848384, "REMICADE": 19.43885152314032, "SPIKEVAX": 0.364320669098827, "STELARA": 5.471374774644078, "VAXZEVRIA": 0.1051718744502363, "null": 0.4081054062567946}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5654.json
index 9eacc72c033..c37d895788b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5654.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5654.json
@@ -1 +1 @@
-{"AFINITOR": 117.59567765322556}
\ No newline at end of file
+{"null": 6.531832504582576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5655.json
index e0ce9fbb425..6f847dacf5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5655.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5655.json
@@ -1 +1 @@
-{"AFINITOR": 224.0023327940353}
\ No newline at end of file
+{"null": 0.5059414636737627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5656.json
index ca086e31ec7..3b7df148c79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5656.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5656.json
@@ -1 +1 @@
-{"null": 1.1605127259847858}
\ No newline at end of file
+{"ABACAVIR": 4.3398256019239785, "ARIPIPRAZOLE": 23.52138364077873, "AVANDIA": 5.018453519998397, "COMIRNATY": 0.2113639846735422, "ENTRESTO": 13.061225053515928, "OLANZAPINE": 3.141563700545401, "ZYPREXA": 6.47134708074725, "null": 1.4720908274753297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5657.json
index 97ecbaafa50..6e8b1441929 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5657.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5657.json
@@ -1 +1 @@
-{"AIMOVIG": 55.87139936988857}
\ No newline at end of file
+{"COMIRNATY": 0.1821711819914555, "CYMBALTA": 4.294621411714628, "RINVOQ": 23.29461949501023, "ROACTEMRA": 25.145523410847517, "null": 0.7910456200456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5658.json
index 1438b0f1bf5..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5658.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5658.json
@@ -1 +1 @@
-{"AUBAGIO": 4.33717106904458, "CYMBALTA": 1.452919858851772, "GARDASIL": 4.093308835175206, "KEPPRA": 5.055716130057183, "OCEAN": 768.5327563352045, "ZOSTAVAX": 3.1323021500467965, "null": 1.5519528442114006}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5659.json
index 4b8138aa7e9..80c417840b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5659.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5659.json
@@ -1 +1 @@
-{"null": 1.1383648476345771}
\ No newline at end of file
+{"ELIQUIS": 57.85408542160759, "null": 0.7686757609157693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/566.json
index 87a727ebb4e..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/566.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/566.json
@@ -1 +1 @@
-{"DOCETAXEL": 15.012815887936876, "FILGRASTIM": 124.04884208021328, "HERCEPTIN": 19.790133136971345, "KEYTRUDA": 3.1345859926033364, "PEGFILGRASTIM": 613.5579472683735, "null": 2.393703955661359}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5660.json
index 68f7eb5f810..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5660.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5660.json
@@ -1 +1 @@
-{"TOZINAMERAN": 5.124071134384604}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5661.json
index 6d6df2a3493..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5661.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5661.json
@@ -1 +1 @@
-{"SPIRONOLACTONE": 249.3962780602105}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5662.json
index 6e062f00b73..29ebdbddff9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5662.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5662.json
@@ -1 +1 @@
-{"ABILIFY": 15.226735240454625, "ARIPIPRAZOLE": 16.891524258120143, "ASENAPINE": 19.97782218049421, "CARBIDOPA": 14.682078768238997, "COMTAN": 17.09824342074636, "CYMBALTA": 1.0793868271082698, "DEXMEDETOMIDINE": 6.936658181368837, "DULOXETINE": 2.419431431127692, "ENTACAPONE": 19.767517285193183, "ESOMEPRAZOLE": 11.86522508139484, "FENTANYL": 1.6891532133026568, "HYDROCORTISONE": 1.4316095257616477, "INVEGA": 21.885678113490577, "LATUDA": 11.85959994627396, "LEVODOPA": 17.41257569686684, "LOXAPINE": 22.794503539131547, "LURASIDONE": 20.48484485657965, "MIDAZOLAM": 1.2875350447122935, "OLANZAPINE": 56.44518718288362, "PALIPERIDONE": 45.18296401804053, "PREGABALIN": 1.623889793876824, "RISPERIDONE": 17.142879721773358, "STALEVO": 3.49465684394376, "SYCREST": 59.92183755876987, "XEPLION": 37.12060238203841, "ZYPADHERA": 4.160085951465657, "ZYPREXA": 43.50682076135289, "null": 2.770869038728204}
\ No newline at end of file
+{"SUBOXONE": 51.0787967590382, "null": 0.5226776930269966}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5663.json
index c9d536ea308..1461494e85b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5663.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5663.json
@@ -1 +1 @@
-{"ALISKIREN": 823.7237790575595, "ELIQUIS": 3.0974762050922178}
\ No newline at end of file
+{"null": 1.92648097981972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5664.json
index 798b64fce8a..12c230d9634 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5664.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5664.json
@@ -1 +1 @@
-{"CASPOFUNGIN": 22.90979267784319, "CICLOSPORIN": 5.577161593119884, "CYTARABINE": 6.556559817281046, "KYMRIAH": 19.10260970130401, "LEVETIRACETAM": 9.669998720543736, "METHOTREXATE": 3.8714090403081256, "SOLIRIS": 6.687708171394188, "null": 1.1933303896361778}
\ No newline at end of file
+{"INFANRIX": 392.15024004063065, "null": 1.7594257260330517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5665.json
index 1846177c6a3..d890b539eb6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5665.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5665.json
@@ -1 +1 @@
-{"SPINRAZA": 194.5464689476435}
\ No newline at end of file
+{"CICLOSPORIN": 7.183465893729113, "COMIRNATY": 0.2371413292451294, "GLYCOPYRRONIUM": 109.3371858324765, "NEXAVAR": 8.536389729584071, "SPIKEVAX": 0.263241150153693, "TOZINAMERAN": 0.6358372481778055, "null": 0.3994901765592462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5666.json
index 70c8349f1db..14ef932c862 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5666.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5666.json
@@ -1 +1 @@
-{"SPINRAZA": 1658.1405853221372}
\ No newline at end of file
+{"ABATACEPT": 9.402012568945342, "ADALIMUMAB": 6.034546633512429, "APIDRA": 0.9623724482810814, "APREMILAST": 19.70174355969116, "ARAVA": 16.90481630074737, "ATRIPLA": 10.137160501496668, "BENLYSTA": 2.5896586722377584, "BYETTA": 0.750079556516029, "CAPECITABINE": 1.2746347472557806, "CICLOSPORIN": 0.7770790813442094, "CIMZIA": 3.717132529579189, "COSENTYX": 0.7438699281057666, "ELIQUIS": 0.5436406969072245, "ENBREL": 2.251945628693864, "EVISTA": 3.944881534710202, "EXJADE": 0.6454051513137607, "FENTANYL": 0.4142272848394123, "FORSTEO": 3.598758391775771, "HUMALOG": 0.2726117195173695, "HUMIRA": 1.4786784515575049, "HYDROCORTISONE": 3.6720751501504094, "IBRANCE": 0.9082689742717196, "JANUMET": 1.4818156584643876, "JANUVIA": 1.2509146112409764, "JARDIANCE": 1.1352364252318743, "LANTUS": 1.3604307971051866, "LEVEMIR": 1.7453580535327886, "METHOTREXATE": 0.6119125399186623, "OMALIZUMAB": 1.1614928095894237, "OPSUMIT": 1.4001316538938098, "PEGASYS": 0.1533946023157344, "PLAVIX": 0.4404073936817266, "RINVOQ": 0.9445017017657646, "RITUXIMAB": 0.7261398658842213, "SIMPONI": 7.946865655193645, "STELARA": 1.6119894748716923, "STRIBILD": 6.665369088413817, "TOZINAMERAN": 0.0545876395375011, "TRACLEER": 0.8742242104281012, "TRELEGY": 3.2806828319985364, "TRUVADA": 6.418942258890757, "VIREAD": 1.9103647093611624, "XELJANZ": 2.7117703209909, "XOLAIR": 0.4275131402701188, "XTANDI": 0.8643920253977343, "ZOSTAVAX": 4.230456427105719, "null": 0.3963177248694269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5667.json
index 63494a0206e..d150c8db092 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5667.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5667.json
@@ -1 +1 @@
-{"ABACAVIR": 2.1239278787773963, "ANORO": 136.99192218843612, "APIXABAN": 19.34594258814763, "AZATHIOPRINE": 8.177357930385789, "CAELYX": 3.571900301581749, "CICLOSPORIN": 1.9706919611067144, "GARDASIL": 2.9425877240799285, "KEYTRUDA": 1.023722649370033, "OLANZAPINE": 1.1054989146225704, "ROTASHIELD": 123.43464368199488, "SHINGRIX": 1.4599056537462856, "SOLIRIS": 1.4090615603265686, "TAMIFLU": 2.036530638883425, "TOZINAMERAN": 1.923331168341187, "VFEND": 1.4570746994045531, "YESCARTA": 3.932976493530116}
\ No newline at end of file
+{"ARAVA": 4.39205658893626, "null": 0.6316770099604113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5668.json
index 3a950c83a13..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5668.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5668.json
@@ -1 +1 @@
-{"null": 1.162750327229765}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5669.json
index da7647dafb7..61349c74e11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5669.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5669.json
@@ -1 +1 @@
-{"BRIDION": 287.7867726350917, "FENTANYL": 38.00750708633272, "SUGAMMADEX": 783.3574580078387, "null": 4.390618781840559}
\ No newline at end of file
+{"AFINITOR": 0.2742096205816408, "AIMOVIG": 0.3563427366891121, "ANORO": 1.1048072580219288, "APIDRA": 1.3242303547457936, "ARANESP": 2.9060215694465965, "ATRIPLA": 7.150603043788784, "AUBAGIO": 1.056176796159192, "AVANDIA": 0.7647596142477888, "BENLYSTA": 0.7825296352951157, "BEXTRA": 20.60198940620528, "BONVIVA": 4.057248599655636, "BOSULIF": 1.3904745675461927, "BUDESONIDE": 0.5666592032556887, "BYDUREON": 1.0184500041228084, "BYETTA": 0.9036723069179544, "CELECOXIB": 14.259902806493685, "CICLOSPORIN": 0.2236113754839139, "CIMZIA": 0.5061743653044276, "COMIRNATY": 0.00420157290835, "CYMBALTA": 0.4399736035595682, "ELIQUIS": 4.26717962596082, "ENBREL": 1.9670021069737589, "ENTRESTO": 0.9610071459297164, "ESBRIET": 2.445560689560902, "ESOMEPRAZOLE": 2.1949150068811307, "EVENITY": 11.528819794365058, "EVISTA": 24.11011271580117, "EXFORGE": 1.287044534680122, "EXJADE": 3.2707006407485224, "FAMPYRA": 6.351338629766888, "FASLODEX": 2.179901295720906, "FIRDAPSE": 1.631749245481176, "FORSTEO": 5.908190019578335, "GLYCOPYRRONIUM": 4.21348263076589, "HIZENTRA": 1.1712225176168152, "HUMALOG": 3.4040123522881176, "HUMIRA": 0.6136809070261435, "IBRANCE": 4.486981048415546, "INLYTA": 1.3505366746207037, "INSULIN": 0.4406165187568481, "JANUMET": 1.0754039311419816, "JANUVIA": 0.7048710148338017, "JARDIANCE": 1.9419379122185387, "KALETRA": 3.120915373442186, "KEPPRA": 0.5660229065950101, "KEYTRUDA": 0.1600967023872364, "LANTUS": 2.5773849089847944, "LEVEMIR": 2.323229185582808, "LYRICA": 0.8058876572556866, "NPLATE": 0.9219945597497068, "NUCALA": 0.4582294873177569, "OCALIVA": 4.097836635741317, "OFEV": 3.044727896251443, "OPSUMIT": 2.880515850311754, "PANTOPRAZOLE": 4.701995481726397, "PEGASYS": 0.1529313463233587, "PLAVIX": 0.8650469399139095, "RAPAMUNE": 4.302485156603666, "REVATIO": 9.35530300055881, "REYATAZ": 4.0953973062765305, "RITUXIMAB": 0.7239557694442555, "ROACTEMRA": 0.7959312016748353, "SIMPONI": 1.45940609476607, "SOLIRIS": 1.182290347669194, "SPIKEVAX": 0.0409517654037355, "SPINRAZA": 4.253945306229179, "STALEVO": 3.4761500931010025, "STELARA": 0.2408973961103447, "STRIBILD": 5.156764603971011, "SUBOXONE": 1.3233177515593275, "SUTENT": 0.9815197635704136, "TERIPARATIDE": 15.484716274988267, "TOUJEO": 1.89063192112918, "TOVIAZ": 1.7101776518462577, "TOZINAMERAN": 0.121801778474089, "TRACLEER": 2.583591211890956, "TRELEGY": 8.814922875814164, "TRUVADA": 6.635462243554665, "VELTASSA": 4.809590408597058, "VFEND": 2.136264593125449, "VIAGRA": 1.047843695812947, "VIREAD": 5.453202905620159, "VOTRIENT": 1.685743049565227, "XALKORI": 1.88060008896686, "XELJANZ": 4.683704862035591, "XOFIGO": 2.172773961450536, "XTANDI": 3.95226414268878, "ZOSTAVAX": 0.7382681911341922, "ZYPREXA": 0.6406299938884069, "null": 1.220313207454447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/567.json
index 958942651d2..c34e77819d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/567.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/567.json
@@ -1 +1 @@
-{"null": 1.4952445862083286}
\ No newline at end of file
+{"ABATACEPT": 3.5056966125328723, "ADALIMUMAB": 1.2707618555590083, "ARAVA": 4.494375245486609, "BUSULFAN": 4.573184472452145, "CIMZIA": 4.855441324347547, "COMIRNATY": 0.073181805562493, "COSENTYX": 2.237241184053005, "ENTYVIO": 46.85057827260443, "FORXIGA": 6.814915019608272, "HUMIRA": 4.176275151285838, "INCIVO": 11.879287286122594, "JARDIANCE": 11.00421257309361, "NEXAVAR": 3.717694595348619, "PEGASYS": 1.526958314169339, "REMICADE": 17.075151057943053, "SIMPONI": 4.160748136818152, "STELARA": 14.177264879162497, "STIVARGA": 4.952402543059005, "SUTENT": 4.059616054555711, "XELJANZ": 1.5880486903595028, "null": 0.4201773187604315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5670.json
index 23ed52dcd85..627f211cfb2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5670.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5670.json
@@ -1 +1 @@
-{"FENTANYL": 14.29982238485408, "SUFENTANIL": 151.23454294364646, "SUGAMMADEX": 1233.7163544188072, "null": 3.4457302777719123}
\ No newline at end of file
+{"ARAVA": 0.6570976118845425, "ATRIPLA": 2.415638287910548, "BENLYSTA": 3.567568354149594, "CIMZIA": 3.1391986460072365, "COMBIVIR": 29.4247876783338, "ELIQUIS": 1.518356086569469, "ENBREL": 2.414197114852868, "EXJADE": 2.9352915188951987, "FORSTEO": 4.1271030528084, "IBRANCE": 3.28686764811359, "IRON": 28.532415485192693, "JARDIANCE": 1.815981014090416, "KALETRA": 4.53135758467981, "LANTUS": 2.4648399291029097, "NAGLAZYME": 18.805963814719306, "OPSUMIT": 3.282301750001958, "SAXENDA": 5.885408695448563, "SIMPONI": 11.070922095671053, "STELARA": 2.446106253778405, "STRIBILD": 3.8955786074570313, "TRACLEER": 4.4099615264416165, "TRELEGY": 7.262154816001967, "TREMFYA": 11.314596563888683, "TRUVADA": 0.5847439854865516, "VOTRIENT": 7.112025275118933, "XELJANZ": 5.591662547681602, "null": 1.122057541799798}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5671.json
index 5785e707ddb..407f03f0aca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5671.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5671.json
@@ -1 +1 @@
-{"null": 15.590822419093616}
\ No newline at end of file
+{"ASPARAGINASE": 167.13486459068065, "null": 0.6659916929566059}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5672.json
index 1e6e953bd68..ac5c80f84f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5672.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5672.json
@@ -1 +1 @@
-{"COMIRNATY": 2.265036149485321}
\ No newline at end of file
+{"CICLOSPORIN": 32.48539541837922, "COMIRNATY": 0.117290652057222, "GARDASIL": 2.257764834363822, "OLANZAPINE": 8.27568154536018, "null": 2.206878937095164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5673.json
index 232a8a565d9..12c4a05f6f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5673.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5673.json
@@ -1 +1 @@
-{"null": 1.8177662466906612}
\ No newline at end of file
+{"COMIRNATY": 2.7882544816507413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5674.json
index eb4cd2f34ca..dccef158be1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5674.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5674.json
@@ -1 +1 @@
-{"BETAFERON": 36.07455045600889, "COMIRNATY": 1.2105163488506514, "GARDASIL": 5.663523013688188, "ROACTEMRA": 10.641241399405978, "SOLIRIS": 43.3034429151255, "TOZINAMERAN": 1.3822472733009443, "VAXZEVRIA": 1.1962990964730371}
\ No newline at end of file
+{"COMIRNATY": 4.137099191996298, "SPIKEVAX": 1.4464498678978743, "TOZINAMERAN": 0.6543363418424886, "VAXZEVRIA": 0.5640411702207184, "null": 0.5689253728505743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5675.json
index c0066dd645f..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5675.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5675.json
@@ -1 +1 @@
-{"GARDASIL": 2.4396592543916027, "KEYTRUDA": 2.317973310484395, "LEVETIRACETAM": 19.54209077248775, "null": 2.280959455756404}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5676.json
index 87d0950afa1..befd5bd7fd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5676.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5676.json
@@ -1 +1 @@
-{"HUMALOG": 41.50460065641253, "LANTUS": 7.403955855428577, "OPTIMARK": 19.30969205579556}
\ No newline at end of file
+{"COMIRNATY": 0.4750033096468884, "SUFENTANIL": 233.4923689841373, "null": 0.7124067480939676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5677.json
index f75c0bc2044..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5677.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5677.json
@@ -1 +1 @@
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\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5678.json
index 19d068601ec..1362920bbcf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5678.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5678.json
@@ -1 +1 @@
-{"BIKTARVY": 118.46683606821615}
\ No newline at end of file
+{"COMIRNATY": 1.4598683064362097, "null": 0.2974667307030956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5679.json
index 28215d32794..dd4335c6062 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5679.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5679.json
@@ -1 +1 @@
-{"EFAVIRENZ": 24.485149034334952, "EMTRICITABINE": 103.25528014840788, "LEVETIRACETAM": 7.691601974956101, "null": 6.357208008222257}
\ No newline at end of file
+{"ARAVA": 11.067568365815692, "null": 1.7945837226228631}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/568.json
index f3fd5e2b5aa..d29c5ae7700 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/568.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/568.json
@@ -1 +1 @@
-{"CHLORHEXIDINE": 25.90289805646156, "OLANZAPINE": 6.864923034946712, "ZYPREXA": 11.130878533341958, "null": 1.9260590713245411}
\ No newline at end of file
+{"APTIVUS": 952.249070345796, "COMBIVIR": 36.07291863631076, "null": 2.8970744058844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5680.json
index dff04b09607..1a6d73c0f72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5680.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5680.json
@@ -1 +1 @@
-{"COMIRNATY": 1.8862256856457968, "MEPOLIZUMAB": 31.64167749954049}
\ No newline at end of file
+{"null": 2.064126026423565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5681.json
index d590c8dd5bd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5681.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5681.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 10.273899666770747, "CHAMPIX": 4.857320177532466, "COMTAN": 66.36416249117842, "PEGINTRON": 11.744435572666768, "null": 1.779606857061301}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5682.json
index 8d8b5503ba8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5682.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5682.json
@@ -1 +1 @@
-{"ALIMTA": 1.026155911564335, "ARIPIPRAZOLE": 1.8590280557829333, "ASPARAGINASE": 14.2011200632041, "AVASTIN": 11.859621701008011, "AXICABTAGENE": 96.237660765208, "BEVACIZUMAB": 20.21455008908868, "BLINATUMOMAB": 14.123888559518909, "BORTEZOMIB": 5.8134152823756295, "BREYANZI": 107.81329337021144, "BUPIVACAINE": 4.582403595753855, "BUPRENORPHINE": 1.0568023435400238, "BUSILVEX": 12.943401651148482, "BUSULFAN": 6.265438266096305, "CAELYX": 2.080584492222345, "CAPECITABINE": 12.135852915879894, "CETUXIMAB": 8.372217811797878, "CICLOSPORIN": 7.172991543039554, "COLISTIMETHATE": 38.40526030714968, "CYTARABINE": 5.400012623858544, "DESCOVY": 8.714819067114021, "DEXAMETHASONE": 2.212188367002649, "DOCETAXEL": 4.2277405777198, "DOXORUBICIN": 1.6868859354553865, "DULOXETINE": 1.6685679086684504, "EFAVIRENZ": 2.437111596279093, "EMTRIVA": 24.573582278336744, "FAMPRIDINE": 15.890887142486475, "FENTANYL": 2.2358258002870186, "FILGRASTIM": 4.538518941240761, "HALAVEN": 6.94467427494983, "HERCEPTIN": 1.6116032091734411, "IMATINIB": 4.388141512395203, "INTELENCE": 19.471394046635037, "IRINOTECAN": 16.67839111290034, "ISENTRESS": 3.297971421175697, "JEVTANA": 3.971893911862381, "KYMRIAH": 66.64143421379781, "LACOSAMIDE": 14.167596075578876, "LEVETIRACETAM": 1.5504386095296527, "MABTHERA": 2.570163794905357, "METHOTREXATE": 2.313545862303196, "MIDAZOLAM": 1.528578517057832, "NEULASTA": 1.2163540358842158, "NOXAFIL": 6.764302951957865, "OLANZAPINE": 1.4348549061348648, "PACLITAXEL": 4.980259111635566, "PANITUMUMAB": 29.940356339272107, "POSACONAZOLE": 15.0974259307694, "RISPERIDONE": 4.223653893050045, "TACROLIMUS": 11.378608573956864, "THALIDOMIDE": 4.854351083876428, "THIOTEPA": 10.093362038127054, "TISAGENLECLEUCEL": 33.45867697076864, "TIVICAY": 23.15917344924086, "VECTIBIX": 23.748500805987835, "VFEND": 2.245860206919485, "VORICONAZOLE": 12.809669691928049, "XELODA": 7.1808520378960266, "YESCARTA": 343.4460247622447, "null": 1.5210227822422686}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5683.json
index 5c2c81c1e54..d728615f792 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5683.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5683.json
@@ -1 +1 @@
-{"null": 2.2215263940755143}
\ No newline at end of file
+{"null": 2.90040005488522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5684.json
index d2d245bc31d..2bcc13482e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5684.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5684.json
@@ -1 +1 @@
-{"ZOSTAVAX": 106.38086844845338}
\ No newline at end of file
+{"ENTYVIO": 21.14950598665603, "SIMPONI": 10.35452358996506, "null": 0.494456145726517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5685.json
index e5b43619775..0df33aaba10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5685.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5685.json
@@ -1 +1 @@
-{"ARANESP": 38.11223478447088, "EPOETIN": 361.4433936119351, "null": 2.838782617585562}
\ No newline at end of file
+{"MYCOPHENOLATE": 100.02330172977037, "null": 0.316676073089126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5686.json
index 2fbf2ffba4c..798344088db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5686.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5686.json
@@ -1 +1 @@
-{"ABEMACICLIB": 4.333271677969338, "ABRAXANE": 3.59197947071274, "ACCOFIL": 15.908291807085313, "ADCETRIS": 16.77784833495564, "ADVAGRAF": 4.757569884751916, "AFLIBERCEPT": 6.855846559771462, "ALEMTUZUMAB": 2.770013540322416, "ALIMTA": 8.532196322030602, "ALOXI": 2.164915742137972, "ALPELISIB": 1.021249839755706, "ALYMSYS": 25.443533426929605, "AMIKACIN": 1.0327902603505523, "ANIDULAFUNGIN": 8.283197941217677, "APROVEL": 1.0959027231570264, "ARIPIPRAZOLE": 2.402313699072564, "ARIXTRA": 1.1933323125833415, "ARZERRA": 6.518697438948528, "ASPARAGINASE": 4.752217137987931, "ATEZOLIZUMAB": 1.4921761316824054, "ATRIANCE": 26.723945494716958, "AUBAGIO": 1.2075710721180533, "AUTOLOGOUS": 35.42540171394921, "AVASTIN": 6.732960282702266, "AXICABTAGENE": 7.847349187259715, "AYBINTIO": 32.3138873188415, "AZACITIDINE": 16.005021914560267, "AZATHIOPRINE": 1.880393461599028, "AZTREONAM": 1.4088954410350223, "BASILIXIMAB": 2.427631852611056, "BEVACIZUMAB": 9.664512777770453, "BINOCRIT": 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\ No newline at end of file
+{"null": 1.87083069145616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5687.json
index e3dd9fc9d77..4186d705485 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5687.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5687.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 315.0970474243834, "REMICADE": 157.16266732289336}
\ No newline at end of file
+{"ADALIMUMAB": 0.8404849883351992, "ADCETRIS": 304.809430858085, "ARAVA": 0.3813084385471809, "ATRIPLA": 1.201749070776099, "BRENTUXIMAB": 509.8437675637159, "CARMUSTINE": 33.858763843380395, "CELLCEPT": 3.175014220263382, "CHLORMETHINE": 281.84869809354905, "CICLOSPORIN": 7.6017017265821, "CIMZIA": 1.147749360982762, "COMIRNATY": 0.2272544161389338, "COSENTYX": 1.7408602223573912, "CYTARABINE": 8.940471354094425, "DOXORUBICIN": 8.221703260208425, "GARDASIL": 3.678976217053104, "HUMIRA": 4.5711698335401305, "KALETRA": 5.964195033071367, "METHOTREXATE": 2.8893114503999877, "RITUXIMAB": 15.223947930808542, "SIMPONI": 4.140082487027561, "STELARA": 5.671002222119986, "TREMFYA": 10.787445686135934, "XELJANZ": 1.235707805649357, "null": 0.5408397807388458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5688.json
index 2cb56b3eabb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5688.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5688.json
@@ -1 +1 @@
-{"ASPARAGINASE": 35.58110644337845, "AZACITIDINE": 31.263827805238563, "BUSULFAN": 16.35751232270599, "CLADRIBINE": 98.72312854272454, "CYTARABINE": 30.74581354202947, "DEXAMETHASONE": 13.086143321138335, "DOCETAXEL": 23.721687015940727, "IRINOTECAN": 18.142800601224515, "MELPHALAN": 60.461402812124255, "NOXAFIL": 39.42474232419959, "PEMETREXED": 26.199465956507265, "TRODELVY": 264.3894184690821}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5689.json
index e11eb6f8465..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5689.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5689.json
@@ -1 +1 @@
-{"CYTARABINE": 68.21820345943779, "JEVTANA": 65.4639443293483, "RITUXIMAB": 17.668595973878624}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/569.json
index a78bd98b7c8..e5d870c811b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/569.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/569.json
@@ -1 +1 @@
-{"ABILIFY": 5.275930599594846, "ARIPIPRAZOLE": 1.759995198313837, "BIKTARVY": 1.7231743651726186, "BRINTELLIX": 4.9283939953229, "BRIVIACT": 4.902148692531389, "BUPRENORPHINE": 1.001654714254277, "CHAMPIX": 6.476834998407813, "COMIRNATY": 1.0670953811984272, "COMTAN": 5.431748990424147, "CYMBALTA": 2.1630539842006167, "DULOXETINE": 3.510957663587796, "EBIXA": 6.05920944286743, "EXFORGE": 1.243215605542146, "FAMPYRA": 1.621720858567678, "FORSTEO": 1.4015560111233654, "FORXIGA": 1.0382138038273383, "FYCOMPA": 4.520259805327356, "HEXYON": 8.161867337607076, "INFANRIX": 6.97649788629731, "KAFTRIO": 3.220992855313835, "KEPPRA": 3.934914570091265, "LACOSAMIDE": 2.3270785485008907, "LATUDA": 4.918695597125134, "LEVETIRACETAM": 3.215824000145393, "LEVODOPA": 14.09673920175693, "MMRVAXPRO": 2.9328853250945754, "OLANZAPINE": 3.939502746445686, "PREGABALIN": 1.506810832878814, "PREVENAR": 3.4146565422771413, "ROTATEQ": 4.533970063022273, "SAXENDA": 1.7716303345219309, "SIFROL": 2.982740107341061, "STALEVO": 2.131198435493688, "SUBOXONE": 1.6437625553885502, "TEDUGLUTIDE": 24.39302440109842, "VIMPAT": 2.0269299023052576, "ZYPADHERA": 1.7488189369496483, "ZYPREXA": 3.716186082816292, "null": 1.5666792997494057}
\ No newline at end of file
+{"STELARA": 10.492368550522537, "null": 1.1557037129504903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5690.json
index b3f5b1481c7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5690.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5690.json
@@ -1 +1 @@
-{"ALIMTA": 13.71526175504257, "ASPARAGINASE": 11.001427394410594, "ATEZOLIZUMAB": 42.51883667150901, "AVASTIN": 3.358737286018038, "AZACITIDINE": 38.46956013909756, "BEVACIZUMAB": 5.831359160009026, "BLINATUMOMAB": 32.165819567441254, "CAELYX": 9.34679140187509, "CARMUSTINE": 42.005298328183, "CYTARABINE": 21.44495738479297, "DEXAMETHASONE": 15.536810774416166, "DOCETAXEL": 7.723748318635585, "DOXORUBICIN": 18.021746827221516, "FILGRASTIM": 19.917272888526316, "GAZYVARO": 16.682693453617606, "HALAVEN": 14.272453684068877, "IBRANCE": 1.744260704535124, "IRINOTECAN": 7.595501674003464, "JEVTANA": 12.716553873488872, "METHOTREXATE": 7.470973468520317, "NEULASTA": 52.52440530302146, "OBINUTUZUMAB": 26.11896152102213, "PEMBROLIZUMAB": 4.578900562803577, "PEMETREXED": 15.810092617644823, "RITUXIMAB": 22.872962403719743, "TRODELVY": 34.953182777898256, "VENETOCLAX": 14.671156167849382, "VYXEOS": 138.48004694764285, "YONDELIS": 40.93582995344361}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5691.json
index 3b67db36121..eb9fe471302 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5691.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5691.json
@@ -1 +1 @@
-{"GANCICLOVIR": 559.0386598035703, "null": 1.074688907439278}
\ No newline at end of file
+{"VENCLYXTO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5692.json
index d213ca5873e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5692.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5692.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 10.35443142948545, "IBRANCE": 3.518592586697804, "KEYTRUDA": 1.956607480834996, "KISQALI": 14.151957148948668, "LEMTRADA": 21.751065209396163, "LENALIDOMIDE": 82.10552000916098, "NEULASTA": 205.1008400856755, "PEGASYS": 5.209846730989928, "TRODELVY": 24.273228276241984}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5693.json
index 3e75fa66a02..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5693.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5693.json
@@ -1 +1 @@
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\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5694.json
index 8ed19a91ff4..8e974da261b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5694.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5694.json
@@ -1 +1 @@
-{"AFINITOR": 1.199846976621057, "ALEMTUZUMAB": 4.250546417397724, "ARIPIPRAZOLE": 37.5973461240653, "AZATHIOPRINE": 10.7690417071381, "BEVACIZUMAB": 4.924103356753341, "CAELYX": 4.85518163478879, "CANCIDAS": 24.08427274796544, "CARBIDOPA": 11.9505496012003, "CICLOSPORIN": 2.397771287751376, "COSENTYX": 1.7725380350409885, "CYTARABINE": 2.6854346104900038, "DEXAMETHASONE": 1.031385198108741, "DOCETAXEL": 3.8817215350565952, "DOXORUBICIN": 3.476272047505969, "ENBREL": 1.909288284202762, "ENTRESTO": 3.0112822457471373, "EXJADE": 3.251296950215474, "FILGRASTIM": 13.52660983739053, "IBRANCE": 1.3542888399885729, "JAKAVI": 9.5737738024387, "KEYTRUDA": 1.6906667811488536, "LEMTRADA": 10.015330921787124, "MEKINIST": 3.194014718298717, "NEULASTA": 17.509674702215186, "OLANZAPINE": 6.995768602379992, "RITUXIMAB": 2.9620141285114108, "RUXOLITINIB": 23.806962190466784, "SOLIRIS": 2.2969193170329643, "XOLAIR": 2.5332110599457502, "ZYPREXA": 2.435738739663856}
\ No newline at end of file
+{"PROTOPIC": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5695.json
index 99f044b86a9..4d43e1baa07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5695.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5695.json
@@ -1 +1 @@
-{"null": 1.0759747915026638}
\ No newline at end of file
+{"DESCOVY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5696.json
index f90e06089b8..573ffeaf613 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5696.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5696.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 27.769461020411832, "CLOPIDOGREL": 4.184973554682112, "JAKAVI": 11.604024378258543, "LEMTRADA": 60.84889620006983, "null": 1.1443285564937835}
\ No newline at end of file
+{"ADCETRIS": 382.1259086586443, "BUSULFAN": 39.87594989406452, "CARMUSTINE": 575.0677120621181, "CHLORMETHINE": 1654.3781031227663, "DOXORUBICIN": 142.66811151216874, "null": 0.4623368707901257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5697.json
index f537c6a9090..583196c8637 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5697.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5697.json
@@ -1 +1 @@
-{"null": 1.2476389963413008}
\ No newline at end of file
+{"PRIVIGEN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5698.json
index e3a6fbc78ce..030666f2ec4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5698.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5698.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 3.744807748740549, "AVASTIN": 5.001843633647941, "BUDESONIDE": 5.577794789043273, "CICLOSPORIN": 1.9596465184318368, "DASATINIB": 47.93547485481319, "DEXAMETHASONE": 4.9973430520409385, "FILGRASTIM": 17.766347641778545, "JANUMET": 5.306298111242307, "LEVOFLOXACIN": 2.789243798216206, "NEULASTA": 7.342697582397224, "NPLATE": 7.265477843620469, "OLANZAPINE": 3.442482096648433, "ROACTEMRA": 4.068980182953355, "RUXOLITINIB": 26.978614278571342, "SUTENT": 1.0521109610055512, "XOLAIR": 1.9238938935552417, "ZYPREXA": 1.605225051981526, "null": 1.3729350299036251}
\ No newline at end of file
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5699.json
index 4d584c84023..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5699.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5699.json
@@ -1 +1 @@
-{"COMIRNATY": 3.0279954715369333, "COVID19": 2.359385446581346, "SPIKEVAX": 3.4537518657525337, "VAXZEVRIA": 2.512091163881199}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/57.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/57.json
index a62ef319817..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/57.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/57.json
@@ -1 +1 @@
-{"ASPARAGINASE": 181.2853996352168}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/570.json
index 8789a00924d..826d4b5830f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/570.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/570.json
@@ -1 +1 @@
-{"FENTANYL": 47.98164838974555, "null": 1.0154320630092648}
\ No newline at end of file
+{"RAPAMUNE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5700.json
index 417a1d2146d..9cf2cbedaea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5700.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5700.json
@@ -1 +1 @@
-{"ANAKINRA": 104.17914485032036, "AZATHIOPRINE": 1014.4020018036178}
\ No newline at end of file
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5701.json
index 84c977243b5..6c7be202c00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5701.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5701.json
@@ -1 +1 @@
-{"null": 24.94847964235029}
\ No newline at end of file
+{"null": 0.9514018175904208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5702.json
index 35e9f0c5392..5ee61b669ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5702.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5702.json
@@ -1 +1 @@
-{"CHAMPIX": 2.912122964207541, "CLOPIDOGREL": 1.1216900413858797, "ZOSTAVAX": 2.352641027342492, "null": 26.203675378634653}
\ No newline at end of file
+{"IBUPROFEN": 76.05493062621257, "null": 2.2781670743824907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5703.json
index 6c13421ffd6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5703.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5703.json
@@ -1 +1 @@
-{"null": 3.339546348012921}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5704.json
index d0a28b7e3b6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5704.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5704.json
@@ -1 +1 @@
-{"ZAVESCA": 73971.8608260369}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5705.json
index 5890447e566..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5705.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5705.json
@@ -1 +1 @@
-{"AIMOVIG": 12.001838663294162, "JETREA": 897.1759333914919, "null": 1.3322904825206294}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5706.json
index 371167c511e..6f97782ffb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5706.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5706.json
@@ -1 +1 @@
-{"ABATACEPT": 7.689297613991, "AMINOSALICYLIC": 1.2938568636600956, "APREMILAST": 2.2905177900150364, "ARAVA": 4.958419837141051, "AZATHIOPRINE": 5.886355105520511, "BRINTELLIX": 6.325316967404075, "BUDESONIDE": 1.057937792824273, "CIMZIA": 1.885590618409964, "CIRCADIN": 3.661918913374096, "COMIRNATY": 1.058551789550818, "COSENTYX": 1.993350931270775, "COVID19": 2.557843516538353, "CYMBALTA": 1.0417350789840096, "DOXORUBICIN": 2.237001474630656, "DULOXETINE": 1.185368945096458, "EFAVIRENZ": 1.1425362814119602, "ENTYVIO": 1.208446956287689, "HYDROCORTISONE": 1.4518905739093055, "IBRANCE": 1.1600502505309738, "IMBRUVICA": 3.34319206782186, "ISENTRESS": 1.5847620275098453, "JAKAVI": 3.353171352384323, "KAFTRIO": 1.0126498599917648, "LAMIVUDINE": 1.7648046194674618, "MICARDIS": 1.2721324590698748, "NUCALA": 3.4829862373181504, "OCALIVA": 1.8431085643328384, "RITUXIMAB": 1.0438157237869636, "RUXOLITINIB": 2.9029705271776423, "SPIKEVAX": 1.265473558310801, "TOZINAMERAN": 1.6912171779852838, "XYREM": 1.4783333371260663}
\ No newline at end of file
+{"FENTANYL": 63.06722349740458, "null": 0.8204645188478649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5707.json
index 7a70014192c..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5707.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5707.json
@@ -1 +1 @@
-{"ABILIFY": 1.963775410342204, "AERIUS": 3.311381588240087, "AIMOVIG": 3.228535423380225, "BETMIGA": 2.382205075119483, "BIKTARVY": 8.013305430925737, "BOTULINUM": 43.24589284850268, "BRINTELLIX": 9.05262022820338, "BRIVIACT": 1.3026493177526133, "CARBIDOPA": 5.149905987150091, "CHAMPIX": 20.71423323981967, "CIRCADIN": 16.279928442093993, "COMBIVIR": 1.1970180471185492, "COMTAN": 1.5940215586855584, "CYMBALTA": 16.040272703168466, "DELAMANID": 1.7857572554695815, "DESLORATADINE": 2.6705397704222027, "EBIXA": 3.1652504543469275, "EDURANT": 12.394255766578366, "EFAVIRENZ": 1.4831091856970384, "ENTACAPONE": 3.683581612399953, "ENTRESTO": 1.1169499778006864, "GENVOYA": 4.244136125566038, "GLIBENCLAMIDE": 1.8155216163857748, "ISENTRESS": 2.226080948038596, "KAFTRIO": 2.7359863225730057, "LATUDA": 2.063048762003044, "LYRICA": 1.120234443122961, "MELATONIN": 16.003497676352573, "RISPERIDONE": 1.490079579695066, "SIFROL": 3.913379328905386, "STALEVO": 2.5097010206155463, "SUSTIVA": 8.542291872123538, "TAMIFLU": 8.08041709435329, "TIVICAY": 5.080839812983594, "TRIUMEQ": 10.760783163387798, "VARENICLINE": 6.521673110084333, "VFEND": 1.3841907770307875, "WAKIX": 13.11133970060878, "XTANDI": 1.1723025005076368, "XYREM": 2.909004273096369, "ZYPREXA": 1.052969960344711, "null": 2.33037598534243}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5708.json
index ff809b71c0b..5fdd91a754c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5708.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5708.json
@@ -1 +1 @@
-{"ACTRAPID": 104.10362586681872, "AP": 3068.614566788939, "AZARGA": 1296.5589549937945, "AZOPT": 1314.909636104503, "CLOPIDOGREL": 5.951958197405623, "DEXAMETHASONE": 5.431982103444282, "IBUPROFEN": 7.656267664893967, "SIFROL": 64.05248677783362, "null": 2.154046336827644}
\ No newline at end of file
+{"ABILIFY": 4.970505984353743, "ARIPIPRAZOLE": 6.960114260619189, "BRINTELLIX": 3.4157772754844067, "BUPRENORPHINE": 2.121751185524717, "CHAMPIX": 21.39171824046908, "CYMBALTA": 6.8065288787294165, "FYCOMPA": 58.91360866932415, "KEPPRA": 3.656746442459725, "LATUDA": 14.177840724623346, "PEGASYS": 11.84520654733562, "PEGINTRON": 16.966296080411045, "SUBOXONE": 5.45247566682297, "ZYPREXA": 3.069224600526086, "null": 2.301750581543654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5709.json
index 0da66012ecf..ff1d65e01a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5709.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5709.json
@@ -1 +1 @@
-{"null": 3.051364619219909}
\ No newline at end of file
+{"CYMBALTA": 2.244146296561926, "OLANZAPINE": 5.192168250645442, "PEGASYS": 2.7195326283713595, "PEGINTRON": 10.86144446340948, "SUBOXONE": 14.887875735121906, "null": 4.915288727675612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/571.json
index 80cbdd4a3ac..b810b2f977d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/571.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/571.json
@@ -1 +1 @@
-{"CICLOSPORIN": 3.683806357713131, "DEXAMETHASONE": 3.3918928028152635, "FENTANYL": 48.86600054913171, "HUMALOG": 2.0033998277186664, "INSULIN": 5.003405455998516, "MIDAZOLAM": 22.055562715950764, "TAMIFLU": 6.689197087648888, "ZYPREXA": 3.910623778748796, "null": 2.59331698936654}
\ No newline at end of file
+{"CIMZIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5710.json
index b307c3db30d..f6cc4db0a54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5710.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5710.json
@@ -1 +1 @@
-{"null": 1.3737295251571595}
\ No newline at end of file
+{"SPRYCEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5711.json
index f7d003cd648..40991961779 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5711.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5711.json
@@ -1 +1 @@
-{"COMIRNATY": 1.5264218121582174}
\ No newline at end of file
+{"BUPRENORPHINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5712.json
index b2e7b6bb632..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5712.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5712.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5713.json
index 67376ef06aa..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5713.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5713.json
@@ -1 +1 @@
-{"COMIRNATY": 1.922589991248297, "ENTRESTO": 3.6366776258785545, "ENTYVIO": 4.679804849207558, "NEXAVAR": 1.917546596334187, "TOZINAMERAN": 1.439863721552169, "null": 1.8218105649760503}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5714.json
index a0b7a84c4a9..09c5760e6bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5714.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5714.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 29.11222027064911, "COMIRNATY": 1.0544639864788643}
\ No newline at end of file
+{"COMIRNATY": 1.0827477025498944, "COSENTYX": 2.833279188586506, "IBRANCE": 1.9099880845188, "KAFTRIO": 63.239252752044855, "PEGASYS": 1.800844623108769, "RINVOQ": 11.088576857376932, "RITUXIMAB": 6.239249150590987, "SHINGRIX": 3.613638084200257, "SPIKEVAX": 0.3852018019050338, "STELARA": 2.228745170083058, "TOZINAMERAN": 1.227782941735606, "VAXZEVRIA": 0.6526474816355206, "XELJANZ": 3.0008036569644183, "ZOSTAVAX": 2.509650643008601, "null": 0.6613982129077923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5715.json
index 4705fd316a7..5921c3c055a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5715.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5715.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 97.54135168891756, "CELECOXIB": 137.6881342924125}
\ No newline at end of file
+{"AIMOVIG": 1.3289590594207028, "BUPRENORPHINE": 3.0175942692027333, "CHAMPIX": 0.6755292955282018, "COMIRNATY": 3.4511085250280664, "CYMBALTA": 0.8007937197113213, "DOXORUBICIN": 18.69116421200922, "GARDASIL": 2.360556084434402, "OMALIZUMAB": 3.615764357212993, "PREGABALIN": 3.2254840803075515, "SPIKEVAX": 1.126180630208803, "TOZINAMERAN": 1.4915654929595268, "VAXZEVRIA": 0.3573542917605672, "ZOSTAVAX": 1.2128311020547409, "ZYPREXA": 0.8685822688533665, "null": 0.8016606918943858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5716.json
index c124f809e98..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5716.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5716.json
@@ -1 +1 @@
-{"ACLIDINIUM": 2.033384056312953, "AERIUS": 5.246008939884965, "ANAKINRA": 9.29073798697564, "ATAZANAVIR": 2.2323945196317108, "BARACLUDE": 3.566535628533104, "BETAFERON": 2.098320871672575, "BUPIVACAINE": 13.158126403706996, "CANCIDAS": 1.8590762995279344, "CELLCEPT": 2.4419241185178486, "COMBIVIR": 1.4626953583393238, "DARUNAVIR": 11.8860103008112, "DOXORUBICIN": 2.1329943953204333, "ELIQUIS": 4.334242680302658, "EMTRICITABINE": 11.87495387159626, "ENBREL": 1.2496180718623362, "ENTYVIO": 1.748806350063096, "EPCLUSA": 1.6454600385400917, "ESOMEPRAZOLE": 1.7755529192271566, "EYLEA": 1.1517548377958078, "FASLODEX": 1.2295664395038357, "FORXIGA": 1.3135153975334577, "GARDASIL": 3.887933854760525, "HEMLIBRA": 4.966154478585073, "HERCEPTIN": 2.3075808163853666, "HIZENTRA": 47.4727639798165, "HUMAN": 36.92807322490231, "HYDROCORTISONE": 1.557128819232559, "ICLUSIG": 2.43393812076235, "ISENTRESS": 4.618797466770805, "LACOSAMIDE": 2.171717353624054, "LANTUS": 1.0430506048862, "LEVETIRACETAM": 1.026327971987804, "LIXIANA": 1.0932830798457642, "LONSURF": 2.6711274281813404, "LYNPARZA": 5.728751473358724, "MIRCERA": 16.87373296956922, "MMRVAXPRO": 2.656756481863554, "NEXAVAR": 1.609352047154578, "OCALIVA": 4.274842085440388, "PEGASYS": 3.959864859315759, "PEGINTERFERON": 1.2090285355799102, "PRIVIGEN": 43.07986275294141, "ROACTEMRA": 12.437043016325376, "ROTATEQ": 1.8334402938561083, "SOLIRIS": 1.1489597471413793, "STIVARGA": 1.3724146427404764, "SUBOXONE": 2.31914639388907, "TAGRISSO": 2.7729909872459397, "TAMIFLU": 11.22079228665147, "TOCILIZUMAB": 5.220093348720895, "VIMPAT": 2.1066351862654185, "XOFIGO": 9.26591997490989, "null": 1.6858846225084865}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5717.json
index c6f6f380814..ce649c7fc44 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5717.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5717.json
@@ -1 +1 @@
-{"COVID19": 2.484105469062831}
\ No newline at end of file
+{"FULVESTRANT": 267.21994105173206, "KISQALI": 127.9005657796427, "RIBOCICLIB": 739.6284857264747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5718.json
index ae0ffae5dc3..013fcc6cee7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5718.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5718.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 17.762404934025476, "AZATHIOPRINE": 12.606180355223923, "BASILIXIMAB": 69.17041958208573, "BUSULFAN": 12.417675481283103, "CELLCEPT": 16.590317693593732, "CICLOSPORIN": 51.32691663873011, "LEVOFLOXACIN": 4.134828548791761, "METHOTREXATE": 4.084859426525982, "MYCOPHENOLATE": 70.4218378211067, "TACROLIMUS": 66.56801510090207}
\ No newline at end of file
+{"EVEROLIMUS": 257.72149654337187, "null": 0.3762194816437627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5719.json
index c1f253d032f..6e4b5e9a957 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5719.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5719.json
@@ -1 +1 @@
-{"ABASAGLAR": 5.710478804883988, "AZILECT": 29.023614939660504, "BETMIGA": 28.62102145270435, "BRAFTOVI": 2.6676686233640123, "BRINTELLIX": 1.775271652918125, "BYETTA": 1.7262903378512169, "CHAMPIX": 3.3100712653689586, "CIRCADIN": 11.33478305423614, "CLOPIDOGREL": 1.538087266173573, "ENTRESTO": 2.5170997443812606, "EXFORGE": 4.784199975429818, "FORSTEO": 2.6123865708179914, "FORXIGA": 13.655739215533105, "JANUMET": 1.901733398917348, "JANUVIA": 1.3152409832347167, "JARDIANCE": 13.61202647174065, "MICARDIS": 3.129573074762157, "OFEV": 1.88618521771482, "OXYBUTYNIN": 15.065990453928755, "PASIREOTIDE": 116.77161584677452, "PEGINTRON": 1.1610849532781786, "TOVIAZ": 18.684595985090297, "XTANDI": 4.564941828923853, "ZOSTAVAX": 2.3678534303632417, "null": 1.9033148644058369}
\ No newline at end of file
+{"ABEMACICLIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/572.json
index 672da946416..0c8bd5cafba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/572.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/572.json
@@ -1 +1 @@
-{"AIMOVIG": 2.924425608295886, "ALISKIREN": 43.04666273680289, "ARIPIPRAZOLE": 1.276005735999426, "AUBAGIO": 1.889069794194286, "AZILECT": 9.769345836094898, "BENLYSTA": 1.3098870910114555, "BOTULINUM": 4.2677612393737565, "BRILIQUE": 1.1431765761904829, "BRIVIACT": 2.0319974394952047, "BUPIVACAINE": 1.5946786580555965, "CLOPIDOGREL": 2.054712868220362, "COMIRNATY": 1.1278434697005892, "CYTARABINE": 1.4156949125478318, "DOLUTEGRAVIR": 3.722706740607183, "DULOXETINE": 1.1396402437355102, "ELIQUIS": 1.6027572022100842, "ENOXAPARIN": 2.369484532299894, "ESOMEPRAZOLE": 1.515900471173869, "EVISTA": 1.6110849378933156, "EYLEA": 1.292718671112598, "FESOTERODINE": 49.54845343347981, "FILGRASTIM": 1.6498277102413703, "FIRDAPSE": 2.173363708595058, "ICLUSIG": 1.530538072403244, "INFANRIX": 1.89799243290278, "IRBESARTAN": 1.93744620561695, "IRINOTECAN": 1.578646493981358, "KEPPRA": 3.311014649204485, "KYMRIAH": 3.975692058042827, "LACOSAMIDE": 2.749392822087687, "LANTUS": 1.3001945370834216, "LEMTRADA": 1.0921424894449931, "LEVETIRACETAM": 1.6958060882093058, "LIXIANA": 1.0275256205157628, "LYRICA": 1.285754415904378, "MISOPROSTOL": 20.773318408665148, "NOVONORM": 4.743917001567636, "OFEV": 1.3410409772376926, "PEGINTRON": 1.100576499012609, "PLAVIX": 1.3831114993387397, "RISPERIDONE": 1.3316729064035044, "RIVAROXABAN": 2.8177158397889865, "RUBRACA": 1.069112771105312, "STALEVO": 1.4272926026276518, "TASIGNA": 1.5317848174622335, "TEMODAL": 2.680491570203874, "TEMOZOLOMIDE": 3.804293192407808, "THALIDOMIDE": 1.76463613058725, "VIMPAT": 2.75008718179607, "YESCARTA": 13.946453313172247, "ZYPADHERA": 1.6045716574402693, "null": 1.3164806894838923}
\ No newline at end of file
+{"null": 1.250315058628196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5720.json
index 8abe73f3a5a..ce43ba14c12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5720.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5720.json
@@ -1 +1 @@
-{"ACLIDINIUM": 102.4710127386318, "BRILIQUE": 47.27474268299163, "NUCALA": 5.38451150271531, "null": 1.7500196449020675}
\ No newline at end of file
+{"ABIRATERONE": 497.7202871067497, "APALUTAMIDE": 357.33944216139383, "CABAZITAXEL": 843.3002878261087, "DOCETAXEL": 31.411306147416752, "JEVTANA": 42.107361549761535, "NUBEQA": 1055.486014613139, "PLUVICTO": 628.3275672818521, "XOFIGO": 2530.7950590700366, "XTANDI": 10.83061766443097}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5721.json
index 3cdc7be51df..cf4c698f063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5721.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5721.json
@@ -1 +1 @@
-{"null": 2.7083890562614026}
\ No newline at end of file
+{"BUPIVACAINE": 42.94025635460892, "COMIRNATY": 0.4257964922299266, "FENTANYL": 64.91297083447648, "SUFENTANIL": 157.79323117684072, "null": 1.4144106174825508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5722.json
index af938249150..f3a3c6e3456 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5722.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5722.json
@@ -1 +1 @@
-{"null": 8.735195699572643}
\ No newline at end of file
+{"ALIMTA": 17.62796954419729, "AUBAGIO": 3.538997609700999, "FIRDAPSE": 31.54554206505523, "KEYTRUDA": 11.290984229118711, "MEKINIST": 10.618065064286146, "OPSUMIT": 16.389299527296895, "TRELEGY": 13.541043846682433, "VELTASSA": 109.95741889958036, "VOTRIENT": 88.34323587239946, "XTANDI": 9.104758627401148, "null": 0.6801734016852156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5723.json
index 89c7fe1f0c9..c0fcd8884be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5723.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5723.json
@@ -1 +1 @@
-{"FENTANYL": 3.9543557923764863, "IRBESARTAN": 13.49443218263164, "LACOSAMIDE": 16.04346081937672, "null": 7.916898692157472}
\ No newline at end of file
+{"ABATACEPT": 0.0675469222158941, "ABILIFY": 0.9925085351199102, "ADCIRCA": 6.2916768251943065, "ADEMPAS": 4.697665291767141, "ALEMTUZUMAB": 0.2899044802245244, "ALIMTA": 0.8337940706585063, "AMBRISENTAN": 2.973524653144432, "AMINOSALICYLIC": 1.0550456441767824, "ANORO": 2.3189500030345624, "APIDRA": 2.695315416351243, "APIXABAN": 5.1486048875940025, "APREMILAST": 0.4239368218477305, "ARANESP": 19.469962326052077, "ARAVA": 0.5634982728025817, "ARIPIPRAZOLE": 2.444068576044516, "ARIXTRA": 1.9319975021695237, "ATAZANAVIR": 1.057905394433909, "AUBAGIO": 4.612301912232184, "AVAMYS": 3.246056786669453, "BARACLUDE": 3.7727952993017633, "BEDAQUILINE": 0.4808830296489106, "BENLYSTA": 5.406711289728703, "BETAFERON": 0.9434617662286672, "BRINTELLIX": 0.6248832895872051, "BRIVIACT": 1.364294011590692, "BUDESONIDE": 0.4075034109692448, "BUMETANIDE": 2.973341954330259, "BUPIVACAINE": 2.588873938442315, "BUPRENORPHINE": 2.111509180717235, "BYETTA": 1.2472540796071474, "CABOMETYX": 0.3413831931347277, "CAPRELSA": 7.2893515022466335, "CELLCEPT": 0.5384860436209516, "CIMZIA": 2.8711697256835227, "CINRYZE": 9.845387999048516, "CLOPIDOGREL": 0.2155842718515838, "COMIRNATY": 0.0574399377868218, "CYMBALTA": 1.2722440593091082, "DARZALEX": 0.8283492955849413, "DESCOVY": 1.5948474720230783, "DEXAMETHASONE": 0.3448096705654804, "DUPIXENT": 5.066538717516255, "ELIQUIS": 4.295685582294421, "ENBREL": 0.1150229238570142, "ENTYVIO": 1.0501311181570516, "ERLEADA": 2.01637817523183, "ESOMEPRAZOLE": 0.9235950944289842, "EVENITY": 1.1986281136719066, "EVISTA": 0.7969494715946505, "EYLEA": 0.5022061994137251, "FENTANYL": 0.2156727316442618, "FIRDAPSE": 2.305664361436756, "FORSTEO": 1.1748167549102888, "FOTIVDA": 4.123921254698673, "GALAFOLD": 3.4804074557423306, "GARDASIL": 0.0632626183068437, "GLYCOPYRRONIUM": 4.657433800374021, "GONALF": 4.700296232353882, "HIZENTRA": 3.6519207747497457, "HUMALOG": 1.266294151650148, "HUMIRA": 1.511083241985378, "HYCAMTIN": 1.7363050894484235, "ICLUSIG": 1.386862432924727, "INCIVO": 0.2932304876055049, "INCRUSE": 9.29241578335014, "INSULIN": 1.3071212630543931, "ISENTRESS": 0.6030095436135926, "JANUMET": 0.5017992127733685, "JANUVIA": 0.3241524380910697, "JARDIANCE": 0.0773941134806782, "KAFTRIO": 7.683136288879194, "KALETRA": 0.7123381863942843, "KALYDECO": 37.40684361066212, "KEPPRA": 1.960579586407083, "KEYTRUDA": 0.5761693277508425, "LAMIRA": 13.920478688864495, "LANTUS": 6.643118912032518, "LEMTRADA": 0.8795928602541664, "LEVEMIR": 3.6788286886646566, "LEVETIRACETAM": 0.370602173111931, "LONSURF": 7.42618719347173, "LYRICA": 0.2900955060606019, "MACITENTAN": 4.62445461845534, "MEKINIST": 2.4543699356278124, "MEPOLIZUMAB": 4.218725899616056, "METHOTREXATE": 0.1470661149359646, "MIMPARA": 3.356559704483112, "MULTAQ": 1.003720535208176, "NEULASTA": 27.17484805106171, "NEXAVAR": 0.6104153040610238, "NINLARO": 3.901504449895852, "NORVIR": 1.4149192298338964, "NOVORAPID": 0.5383830201997657, "NOXAFIL": 1.638487577120708, "NPLATE": 10.694966266236486, "NUCALA": 4.698772421384198, "OCALIVA": 4.310960522177585, "OLANZAPINE": 0.8922090386711502, "OLYSIO": 1.2420218473578295, "OPDIVO": 0.457885609187244, "OPSUMIT": 13.16808153641268, "ORKAMBI": 40.20109797178514, "PEGASYS": 0.3105998601136429, "PEGINTRON": 0.2431550069931897, "PEMBROLIZUMAB": 0.2901471558882957, "PLAVIX": 0.3678475095034912, "PRIVIGEN": 1.5029844315913194, "RELVAR": 2.98429976160136, "REMICADE": 0.5461695240987214, "REVATIO": 0.7050453220301305, "RINVOQ": 1.912736892450822, "RUBRACA": 0.4793188969674117, "RUCONEST": 1.5376011625016068, "SAXENDA": 0.6296302455341037, "SILDENAFIL": 1.1365272596944531, "SIMPONI": 3.209280178551425, "SKYRIZI": 1.917815426310133, "SOLIRIS": 7.728899475393187, "SPIKEVAX": 0.1285026063482832, "SPRYCEL": 12.142961245391785, "STELARA": 1.447426411584417, "STIVARGA": 0.915048677681526, "SUBOXONE": 5.326733779176508, "SYCREST": 3.449759212018085, "SYNAGIS": 14.812632306586348, "TAFINLAR": 3.607536407949742, "TELMISARTAN": 1.4593595690721382, "TERIPARATIDE": 2.0386633959000635, "TIVICAY": 3.4045985499987865, "TOUJEO": 3.132614835169901, "TRACLEER": 3.345196572229051, "TRELEGY": 13.74446748825085, "TREMFYA": 0.8385132330370979, "TRESIBA": 1.0496643963764003, "TRIUMEQ": 3.81080986709355, "VAXZEVRIA": 0.0333571298162419, "VELTASSA": 62.73956667455344, "VENCLYXTO": 3.730798558980714, "VENETOCLAX": 1.996072063999716, "VICTOZA": 1.4342417673389118, "VIMPAT": 3.5551924961600005, "VOTRIENT": 9.68227827480804, "XARELTO": 1.109205215821847, "XOFIGO": 2.315985315993159, "XTANDI": 7.95369580394521, "YERVOY": 2.899782529060089, "ZYPADHERA": 0.4637187439947117, "ZYPREXA": 2.049682089854247, "null": 1.224960434545776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5724.json
index 22f3b64d150..a19bb83c9ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5724.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5724.json
@@ -1 +1 @@
-{"CIALIS": 683.7731034442445}
\ No newline at end of file
+{"AIMOVIG": 32.03647695039577, "CHAMPIX": 9.939555826403968, "CYMBALTA": 5.573615688860079, "FYCOMPA": 23.94001159076202, "KEPPRA": 14.145058934366778, "LATUDA": 10.946057070999917, "LEVETIRACETAM": 7.656645987949806, "LURASIDONE": 134.50611419118653, "OLANZAPINE": 7.5823493384751135, "ZYPREXA": 5.845001153648316, "null": 2.5196024032873963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5725.json
index 8d7c3329849..aa0a624e7b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5725.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5725.json
@@ -1 +1 @@
-{"LAMIVUDINE": 98.9965773969692, "MERCAPTOPURINE": 137.24568877727535}
\ No newline at end of file
+{"ABILIFY": 0.1514893592939974, "ADCIRCA": 2.624695088920644, "ADEMPAS": 1.138832936327557, "AFINITOR": 0.7116295230361308, "AIMOVIG": 1.2892502378612225, "ALEMTUZUMAB": 0.4583421004334491, "AMBRISENTAN": 1.9592791477704663, "APIDRA": 0.2372558102967018, "ARANESP": 0.2131611414067526, "ARAVA": 0.0819567021803383, "AUBAGIO": 0.6494969626171384, "BETMIGA": 0.7539187170426589, "BRINTELLIX": 2.4382160883635016, "BUDESONIDE": 0.3341437555072962, "BUPRENORPHINE": 0.2251379548633294, "BYDUREON": 0.8735975744963338, "CABAZITAXEL": 2.2822218985584697, "CAELYX": 1.963930901381559, "CHAMPIX": 1.1185515810636502, "CICLOSPORIN": 0.2184859002697812, "CIMZIA": 0.2489925230304327, "CIRCADIN": 1.6913688813652905, "CLOPIDOGREL": 0.2703263077928514, "COAPROVEL": 0.953814683276186, "COMIRNATY": 1.8153280480006448, "COSENTYX": 0.4825100704068862, "CYMBALTA": 1.2371366394904904, "CYTARABINE": 0.1857931799948695, "DENOSUMAB": 1.9957039133255363, "DEXAMETHASONE": 0.2017947942527528, "DOCETAXEL": 1.0110595867465415, "DULOXETINE": 0.910531480377163, "ELIQUIS": 0.270006502226402, "ELLAONE": 4.228055623300692, "EMEND": 1.011797874464038, "ENBREL": 0.7433130750700943, "ENTRESTO": 0.1475980899484661, "ENTYVIO": 0.4029686214610208, "ENZALUTAMIDE": 12.857630583700436, "ERLEADA": 9.656146846893924, "ESBRIET": 1.1973341559502544, "ESMYA": 8.709152827239416, "ESOMEPRAZOLE": 0.4493145532316137, "EUCREAS": 1.6120525118588818, "EVENITY": 0.5467653915400508, "EVISTA": 6.523401125198133, "EXFORGE": 0.8194386794520834, "EXJADE": 0.1268835460463767, "FAMPYRA": 0.636106544723759, "FASENRA": 0.5740954374230509, "FASLODEX": 5.226743430294895, "FENTANYL": 0.2896946385142744, "FLEBOGAMMA": 1.0011322484706298, "FORSTEO": 2.079970881909908, "FORXIGA": 0.4456361407690948, "FULVESTRANT": 2.465594847265685, "GARDASIL": 0.8028943207446739, "HERCEPTIN": 1.0660579850718963, "HIZENTRA": 0.5514137177350921, "HUMALOG": 0.1285754630382697, "HUMIRA": 0.2496994825840928, "HYDROCORTISONE": 0.951912538230809, "IBRANCE": 4.069885096739005, "IBUPROFEN": 0.1830540734666563, "IRBESARTAN": 0.9986461063023496, "IRINOTECAN": 0.4358797652629692, "ISENTRESS": 0.6185476209610079, "JANUMET": 0.2895320774185813, "JARDIANCE": 0.2097475514141215, "JEVTANA": 0.7593004825068334, "KEPPRA": 0.2306482201269111, "KEYTRUDA": 0.2048915756666539, "KIOVIG": 0.821889815484774, "KISQALI": 1.7441110884365962, "LANTUS": 0.143603909858098, "LATUDA": 0.3772991916919925, "LEUPRORELIN": 15.19712763704767, "LEVEMIR": 0.2412362414895896, "LEVETIRACETAM": 0.1337568504096307, "LEVOFLOXACIN": 0.1749746071676752, "LIXIANA": 0.5403624794163631, "LYNPARZA": 0.7328073753692337, "LYRICA": 0.4433802918758454, "MEPOLIZUMAB": 0.3048519977614665, "METHOTREXATE": 0.7412082883799056, "MICARDIS": 0.7996647336175768, "MODERNA": 0.4540403733863872, "NEULASTA": 0.5158427195893917, "NEXAVAR": 0.2217702425967842, "NIMENRIX": 0.5737485146374101, "NOT": 0.4667183783556303, "NUBEQA": 4.145841274519624, "NUCALA": 0.2532717588327206, "OCRELIZUMAB": 2.473242295498163, "OLAPARIB": 1.4073164965631415, "OMALIZUMAB": 0.5527371617848746, "OPSUMIT": 0.6007483952645079, "ORGOVYX": 32.71852701561732, "PACLITAXEL": 0.6355481557138857, "PANTOPRAZOLE": 0.6476862004784805, "PEGASYS": 0.3130219090416888, "PEGINTRON": 0.216668899271962, "PERJETA": 1.6707669760546664, "PLAVIX": 0.1806988834499182, "PLEGRIDY": 0.7164311658918175, "PRIVIGEN": 0.7402519337945687, "REMICADE": 0.7096673557429076, "REVATIO": 0.4065539989458975, "RIBOCICLIB": 2.758221051930096, "RINVOQ": 0.4131179928080217, "RITUXIMAB": 0.7557933029599102, "ROACTEMRA": 0.6934292346239108, "RYEQO": 18.619776393643296, "SAXENDA": 0.3502402115425403, "SHINGRIX": 0.3224192509864804, "SILDENAFIL": 1.3014936684363096, "SIMPONI": 0.320839157933812, "SPIKEVAX": 1.243781179988102, "STELARA": 0.8935073640070431, "SUBOXONE": 0.6928975086407372, "SUTENT": 0.3164924819162441, "TASIGNA": 0.2194908227085814, "TAXOTERE": 1.8992359985526055, "TEDUGLUTIDE": 6.604050365706294, "TOZINAMERAN": 1.6847667251506455, "TRACLEER": 0.4825591913311717, "TRULICITY": 0.250424362086227, "VAXZEVRIA": 1.7782062327241894, "VIAGRA": 1.0772830656666212, "VOTRIENT": 0.2702436973243011, "XELJANZ": 0.7638250129665128, "XGEVA": 10.009537814005284, "XOLAIR": 0.6881159089330793, "XTANDI": 9.873220279739709, "ZOSTAVAX": 0.1660874680851232, "null": 0.8797739042834571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5726.json
index 5d62d1ec616..9b7dab00373 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5726.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5726.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.7629899618957945, "AFINITOR": 1.2170566842780624, "AMIKACIN": 4.606356276354017, "ANAKINRA": 21.314026062593165, "ANORO": 85.75191330559532, "APIXABAN": 14.55260144657266, "AZATHIOPRINE": 7.139703819151822, "BENLYSTA": 1.8438689800824477, "BYDUREON": 4.519201336352137, "CELLCEPT": 1.06859784229159, "CICLOSPORIN": 3.1848880448234653, "CIMZIA": 1.3011676794134557, "COSENTYX": 2.669989993338089, "CYTARABINE": 2.241301870784812, "ENBREL": 5.8676192756406085, "FASLODEX": 2.320247137948398, "FULVESTRANT": 2.2788997650081018, "HIZENTRA": 1.4043873600790144, "HUMIRA": 3.267719446534155, "IBRANCE": 1.2249626953208927, "JAKAVI": 1.3423021961968329, "JANUMET": 1.7705084969411042, "LEFLUNOMIDE": 4.696685871091507, "MEKINIST": 1.996236043948864, "MEPOLIZUMAB": 1.0560893434938774, "METHOTREXATE": 7.88998072764187, "NUCALA": 1.900497919408161, "OPTIMARK": 2.628598509815405, "PEMBROLIZUMAB": 1.7870388676911624, "RINVOQ": 1.6272145598043013, "RITUXIMAB": 3.532314893811435, "SIMPONI": 1.191736167429995, "SUTENT": 2.042683594566028, "TOZINAMERAN": 3.397248769884536, "TRULICITY": 1.213250622941854, "VOTRIENT": 1.25423050951957, "XELJANZ": 4.307214026731338}
\ No newline at end of file
+{"COMIRNATY": 0.7427713870357366, "SPIKEVAX": 0.4877171223833214, "VAXZEVRIA": 0.4796129482717964, "null": 1.7599331863273298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5727.json
index e64e4ba9f51..20f534e9914 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5727.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5727.json
@@ -1 +1 @@
-{"null": 1.4682857086670595}
\ No newline at end of file
+{"ADALIMUMAB": 35.954274527187025, "XOLAIR": 156.16425587215184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5728.json
index c3cdf3787d0..e02678ebaf7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5728.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5728.json
@@ -1 +1 @@
-{"ARAVA": 5.497199970593192, "CARMUSTINE": 56.93476936728541, "CELLCEPT": 5.223905296077697, "CICLOSPORIN": 6.213887951092764, "COMBIVIR": 5.592901672522456, "COSENTYX": 1.183719233378684, "CYTARABINE": 7.635581201386291, "DEXAMETHASONE": 2.7672545661177304, "DOXORUBICIN": 6.806077024869822, "ENBREL": 1.358045276950326, "KALETRA": 3.196539742375133, "KYMRIAH": 8.82161451713208, "NPLATE": 15.2589506438617, "PEGINTRON": 1.2938453042430782, "RITUXIMAB": 5.880504835299436, "SIMPONI": 1.6157605783926392, "STELARA": 3.069883371997933, "ZOSTAVAX": 1.0616643780267678, "null": 1.3541502000003474}
\ No newline at end of file
+{"YTTRIUM90": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5729.json
index 72482f3b065..d8a62d9708f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5729.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5729.json
@@ -1 +1 @@
-{"CARMUSTINE": 567.372300187744, "CYTARABINE": 21.526101970521967, "RITUXIMAB": 60.31046632054312}
\ No newline at end of file
+{"ABATACEPT": 31.050882124126453, "ADALIMUMAB": 68.82953584016988, "ANAKINRA": 323.69531670912704}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/573.json
index 68e27700fc1..495272759e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/573.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/573.json
@@ -1 +1 @@
-{"BAVENCIO": 11.55315777248286, "BENLYSTA": 1.7144877051950096, "CELLCEPT": 1.4578541150221578, "CHAMPIX": 1.1484985792221722, "COMIRNATY": 1.027534290684237, "COSENTYX": 1.1560387272068455, "DESLORATADINE": 11.179078206059978, "EXFORGE": 1.3869619490390417, "IBRANCE": 2.112672352822748, "INCRUSE": 4.973774797886219, "INLYTA": 12.147411688353444, "METHOTREXATE": 1.055506386532321, "NUCALA": 2.2660679947393056, "OMALIZUMAB": 3.3723739464537097, "PEGINTRON": 1.2668058165840292, "RELVAR": 30.51226266383044, "REVINTY": 70.56324565898791, "SIMPONI": 1.0134718490649524, "STIVARGA": 2.55817137582958, "TOVIAZ": 2.386394544325944, "TOZINAMERAN": 1.7262770225462594, "TRELEGY": 8.244451803193433, "VOTRIENT": 1.363517335271768, "XELJANZ": 2.5106125352909108, "XOLAIR": 3.0061926110009853, "null": 1.340088857443542}
\ No newline at end of file
+{"null": 1.327642290394438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5730.json
index 2db9c966e67..e3031df22ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5730.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5730.json
@@ -1 +1 @@
-{"ADALIMUMAB": 4.280030763089571, "CIMZIA": 8.973140985549891, "DAPAGLIFLOZIN": 490.2106149003097}
\ No newline at end of file
+{"ASPARAGINASE": 1957.7473921606545, "CYTARABINE": 63.03107189827492}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5731.json
index a8804885137..4a864d3313b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5731.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5731.json
@@ -1 +1 @@
-{"AMPRENAVIR": 683.7381828613328, "ARIPIPRAZOLE": 15.601449555278444, "ASPARAGINASE": 14.418405644262846, "BYETTA": 9.072284187549329}
\ No newline at end of file
+{"null": 0.7056531463719815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5732.json
index d8567205557..c830ee035ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5732.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5732.json
@@ -1 +1 @@
-{"ACTOS": 35.88399149032056, "CYTARABINE": 10.769057248873136, "HUMALOG": 1.4721066868121535, "PEGASYS": 1.0502569077183062, "PEGINTRON": 2.7152423874740137, "PLAVIX": 2.1682345078921483}
\ No newline at end of file
+{"REVLIMID": 86.14338695105104, "null": 5.97691013245312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5733.json
index 4237aa0e9db..b0996f8b4b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5733.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5733.json
@@ -1 +1 @@
-{"FENTANYL": 24.41356537493828, "null": 2.5800671895893976}
\ No newline at end of file
+{"CICLOSPORIN": 236.72246053898985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5734.json
index 5b1e0b1c407..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5734.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5734.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 329.22375476520955}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5735.json
index 9747b0f7249..c0e2309ff65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5735.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5735.json
@@ -1 +1 @@
-{"null": 3.1877485848580447}
\ No newline at end of file
+{"CELLCEPT": 34.230221107425514, "CICLOSPORIN": 12.665167316477438, "null": 2.51411003539644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5736.json
index a715d675b39..936a70d68d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5736.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5736.json
@@ -1 +1 @@
-{"BEOVU": 106.17963605536713, "EYLEA": 5223.992318143326}
\ No newline at end of file
+{"BUSULFAN": 118.40485894852011, "CELLCEPT": 37.27942795700315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5737.json
index eb6c8044672..75bb3e37496 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5737.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5737.json
@@ -1 +1 @@
-{"ARANESP": 396.30123387811545}
\ No newline at end of file
+{"ALEMTUZUMAB": 121.48065411422849, "ASPARAGINASE": 269.4510624146874, "BASILIXIMAB": 52.50389610471233, "BUDESONIDE": 5.107681489634913, "BUSULFAN": 61.97036442351029, "CELLCEPT": 7.216085746802549, "CICLOSPORIN": 15.804533996468992, "CYTARABINE": 37.11896797527905, "EMEND": 56.17913560174131, "MELPHALAN": 85.5061207606328, "MYCOPHENOLATE": 36.96272924040714, "null": 0.3704482912711341}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5738.json
index 827f8056408..203a7774e38 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5738.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5738.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1674483270982428}
\ No newline at end of file
+{"ALEMTUZUMAB": 92.46221198142165, "CICLOSPORIN": 8.050905237836128, "CYTARABINE": 26.09731633108, "null": 1.5382372820079726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5739.json
index 5e77838cedb..635f1d6a4e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5739.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5739.json
@@ -1 +1 @@
-{"ALIMTA": 7.367040542798005, "BEVACIZUMAB": 6.249356195065518, "CLOPIDOGREL": 1.1123139760296794, "CRIZOTINIB": 148.72150343068327, "DABRAFENIB": 13.876856684339211, "DOCETAXEL": 17.51882348616584, "GEFITINIB": 28.23458809957795, "IPILIMUMAB": 14.374157110331277, "IRESSA": 4.371656697444121, "LUMYKRAS": 262.62199792081105, "MEKINIST": 60.33700972276355, "OPDIVO": 430.24269236953, "PACLITAXEL": 10.997894707503384, "PEMBROLIZUMAB": 4.549050977466058, "PEMETREXED": 29.84811142501192, "SOTORASIB": 917.6710243441228, "TAGRISSO": 11.60562978054623, "XALKORI": 94.28499747426464}
\ No newline at end of file
+{"CICLOSPORIN": 51.3265888581136, "CYTARABINE": 32.49040592248048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/574.json
index 4a6f4db0b44..4727dce5e29 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/574.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/574.json
@@ -1 +1 @@
-{"AFINITOR": 10.51274848222767, "AIMOVIG": 1.1722672671559586, "ALIMTA": 1.313833985353151, "APIXABAN": 1.0011781436644582, "AUBAGIO": 1.2610816625425727, "AVELUMAB": 8.374486553079608, "AXITINIB": 3.3673544198793226, "AZATHIOPRINE": 1.0779573005718874, "BEVACIZUMAB": 1.8452317487407588, "BUDESONIDE": 1.02064071801048, "CABOMETYX": 1.696176140302743, "CAELYX": 2.2152020209205, "CAPECITABINE": 1.460422291348441, "CELLCEPT": 2.773493057180294, "CHAMPIX": 1.7088711027282124, "COMPRESSION": 143.07621289750065, "COSENTYX": 4.293180894961076, "COTELLIC": 5.273353831346296, "ENTYVIO": 1.4327816729100185, "ESOMEPRAZOLE": 2.548313943292091, "FASLODEX": 2.233888037302952, "HALAVEN": 3.443729630799968, "HUMIRA": 2.023821222211253, "IBRANCE": 2.166572291530525, "INCIVO": 3.3777359831663016, "ISENTRESS": 2.501575915045517, "JAKAVI": 1.0106999897820697, "KISQALI": 2.5346160377874063, "LAMIVUDINE": 3.518316360843172, "METHOTREXATE": 1.901909162598056, "MMRVAXPRO": 2.1865439005874423, "NEXAVAR": 2.2346349326458785, "PEGASYS": 1.2956888863130744, "PEGINTERFERON": 1.6623037688507507, "PEGINTRON": 1.55685313533385, "RAPAMUNE": 5.9926740554940325, "RINVOQ": 4.783314784655471, "ROACTEMRA": 6.506769765352767, "SIMPONI": 1.1981753242158826, "STELARA": 1.068810823798976, "STIVARGA": 1.197103858093222, "SUTENT": 5.682940200067657, "TAGRISSO": 1.435840271723319, "TORISEL": 9.09863849925276, "null": 1.244759887354263}
\ No newline at end of file
+{"ARAVA": 1.433863909846511, "AZATHIOPRINE": 10.505835585316673, "BUDESONIDE": 2.206003130292276, "CIMZIA": 1.394486948139601, "COMIRNATY": 0.0764179363768323, "ENTYVIO": 15.450398230256704, "HUMIRA": 10.169972050073527, "INCIVO": 11.846661823899442, "INFLECTRA": 100.14735250984732, "PEGASYS": 2.238158940034937, "ROTATEQ": 13.289277331478871, "STELARA": 1.8861146728405347, "SUTENT": 4.543616104988348, "null": 1.15727998773836}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5740.json
index 30dbe4295db..aa465dc727f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5740.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5740.json
@@ -1 +1 @@
-{"ALPELISIB": 332.6209519828068, "PEMBROLIZUMAB": 35.32621984119697, "SOTORASIB": 2736.759079656651, "XALKORI": 149.7730456624511}
\ No newline at end of file
+{"DARUNAVIR": 502.0169625443496, "EFAVIRENZ": 442.46612658309095}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5741.json
index 50b9acd2549..1be55fb5415 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5741.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5741.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 29.17608234903769, "IRESSA": 145.3852755723312, "KEYTRUDA": 16.987094632975086}
\ No newline at end of file
+{"BORTEZOMIB": 897.7776851889981}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5742.json
index 585d94710ad..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5742.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5742.json
@@ -1 +1 @@
-{"null": 4.793129411962667}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5743.json
index 8ec153407f8..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5743.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5743.json
@@ -1 +1 @@
-{"null": 1.3092049495297184}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5744.json
index 25758e8c8e4..91bdc2a8f6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5744.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5744.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0992616884568265, "GARDASIL": 7.371081007566778, "RITUXIMAB": 21.410416223711024, "TOZINAMERAN": 3.3148466642566565, "VAXZEVRIA": 1.0132300519785018}
\ No newline at end of file
+{"GARDASIL": 658.4496585751372, "METHOTREXATE": 5.458314359530697, "STELARA": 3.323267938928645, "null": 0.130076868698487}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5745.json
index faa8ad46ba2..c96c38c69f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5745.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5745.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.4518935993055657, "COMIRNATY": 1.3786843917848264, "IBRANCE": 1.8821940746092685, "SUTENT": 4.421411936043727}
\ No newline at end of file
+{"ALEMTUZUMAB": 92.8784264747334, "BORTEZOMIB": 80.96896438242086, "BUSULFAN": 66.77542573358578, "CELLCEPT": 45.90167139502904, "CICLOSPORIN": 55.08918059254521, "null": 0.1585031204306017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5746.json
index 9aef077cf5e..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5746.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5746.json
@@ -1 +1 @@
-{"COMIRNATY": 2.7552060383857886}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5747.json
index 6834417b3df..c9707d204b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5747.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5747.json
@@ -1 +1 @@
-{"COMIRNATY": 1.5738363695319002, "MMRVAXPRO": 14.41155945541538, "null": 1.098287297167797}
\ No newline at end of file
+{"APIXABAN": 62.17220658164793, "null": 0.363987241145765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5748.json
index e9336d7d58e..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5748.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5748.json
@@ -1 +1 @@
-{"ENOXAPARIN": 291.07510631178434, "FENTANYL": 31.56208891603267, "null": 1.0507248818882962}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5749.json
index b19acd6c6d7..4eb4d281260 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5749.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5749.json
@@ -1 +1 @@
-{"HUMALOG": 3.319821636926553, "HUMIRA": 12.478184811274156, "KEPPRA": 4.064025810870016, "null": 2.303106799524413}
\ No newline at end of file
+{"ATRIPLA": 10.636130754983602, "AVANDIA": 2.492301123866433, "COMIRNATY": 0.0659803018428367, "ELIQUIS": 1.1631616423873712, "EVENITY": 33.35886865017544, "FENTANYL": 1.7565282544828973, "FORSTEO": 14.91403053005988, "HUMALOG": 2.309342195435577, "IBRANCE": 1.5902576567107751, "KALETRA": 11.83041438444896, "LANTUS": 1.0374084560850223, "OLANZAPINE": 3.3323283876414624, "ROACTEMRA": 4.2001624215159055, "STRIBILD": 3.2049474000090923, "TRUVADA": 5.683795462987426, "XELJANZ": 0.9925354868616556, "null": 0.8815564491967071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/575.json
index 16feb834f0d..6f847dacf5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/575.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/575.json
@@ -1 +1 @@
-{"null": 8.80848717857811}
\ No newline at end of file
+{"null": 0.5059414636737627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5750.json
index 5ab8c3b99fe..01f54a7f06a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5750.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5750.json
@@ -1 +1 @@
-{"null": 3.5424778899304763}
\ No newline at end of file
+{"ABILIFY": 86.90837503679627, "OMALIZUMAB": 91.66923873710982, "null": 0.2764125943856398}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5751.json
index f28038783c1..f6e29691c5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5751.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5751.json
@@ -1 +1 @@
-{"null": 3.178702039398656}
\ No newline at end of file
+{"RITUXIMAB": 238.4623629674742, "null": 0.3540582879014698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5752.json
index 5f7949dc942..f3e6f63d09e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5752.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5752.json
@@ -1 +1 @@
-{"null": 1.3814210219558818}
\ No newline at end of file
+{"ABATACEPT": 0.9356857478748082, "ABILIFY": 2.829307817880865, "APIDRA": 10.08146442601987, "ARAVA": 4.238352495309346, "BRINTELLIX": 9.737933802106646, "BYDUREON": 2.4841732744397147, "BYETTA": 3.876722424592612, "CHAMPIX": 2.0013112574652423, "COMIRNATY": 0.3164846452730099, "CYMBALTA": 1.5980890597674111, "ENTYVIO": 2.0643497122275343, "FORXIGA": 5.067605644335838, "GARDASIL": 0.8826876354558295, "HUMALOG": 5.660581193600192, "IBRANCE": 1.699277687120717, "IMATINIB": 11.293136601738532, "INSULIN": 9.04338645212568, "JANUVIA": 3.573810191574963, "JARDIANCE": 4.789695578264968, "LANTUS": 7.104193484273528, "NOVORAPID": 3.887589026100776, "OLANZAPINE": 2.158804045123876, "PEGASYS": 0.5031201417187073, "SAXENDA": 37.143218299659054, "SPIKEVAX": 0.3309625277260258, "SUTENT": 0.7813700871639614, "TASIGNA": 1.922041382358591, "TOZINAMERAN": 0.5174617192387158, "TRULICITY": 7.111055611999341, "VAXZEVRIA": 0.424996158464562, "VICTOZA": 4.773129661526392, "XELJANZ": 0.7677017968026996, "XYREM": 7.412476807352304, "ZYPREXA": 3.0862484602135645, "null": 0.7963914368387963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5753.json
index fde9149f0a5..f23564817c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5753.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5753.json
@@ -1 +1 @@
-{"ATOSIBAN": 168024.3977411458}
\ No newline at end of file
+{"MIMPARA": 1741.8962004735863}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5754.json
index f27e4519ef1..eebf65e696e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5754.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5754.json
@@ -1 +1 @@
-{"ABILIFY": 6.236304935827589, "AIMOVIG": 4.303093242707801, "ANTIBIOTICS": 32.74166895002574, "ATAZANAVIR": 14.06872212636886, "AZATHIOPRINE": 32.666677823068795, "CICLOSPORIN": 5.110929506265864, "CINACALCET": 46.40508512384153, "COMBIVIR": 40.04443202687385, "COSENTYX": 3.969452053546088, "DEXAMETHASONE": 4.5706632322473695, "EFAVIRENZ": 18.83170393825188, "ESOMEPRAZOLE": 8.50720724557446, "FENTANYL": 2.2290312082333186, "IBUPROFEN": 2.9946487638060435, "KALETRA": 3.082574860960762, "KEPPRA": 1.119240885638508, "MIDAZOLAM": 4.363273233136822, "NORVIR": 16.84186026990361, "OLANZAPINE": 2.87799180720436, "OMALIZUMAB": 2.9101533306861342, "OPSUMIT": 1.2754220112462262, "REYATAZ": 47.3521230043124, "SUFENTANIL": 9.741556511994713, "TRACLEER": 3.4407828708352364, "XOLAIR": 14.595419058219372, "null": 1.8277059655526735}
\ No newline at end of file
+{"null": 6.063214573559826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5755.json
index a7ac4f740ce..ba018918af9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5755.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5755.json
@@ -1 +1 @@
-{"null": 1.186077944205506}
\ No newline at end of file
+{"PEGINTRON": 229.9380837770497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5756.json
index 139a8a9b8e2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5756.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5756.json
@@ -1 +1 @@
-{"null": 3.487298748185552}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5757.json
index 8fe651d97a4..97a12c1cdb5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5757.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5757.json
@@ -1 +1 @@
-{"ENTRESTO": 13.617549779275077, "null": 1.8784027870157576}
\ No newline at end of file
+{"SUTENT": 1.8464400303440915, "null": 2.3561106457286263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5758.json
index f124ca91045..9e753b04c39 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5758.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5758.json
@@ -1 +1 @@
-{"ANORO": 386.41575199834926, "APIXABAN": 63.48623105771417, "ARANESP": 17.120467205408225, "AVANDIA": 1.7998484519923332, "AZATHIOPRINE": 21.42457439127578, "BRIDION": 18.677798859335425, "CICLOSPORIN": 1.2460219840170217, "CLOPIDOGREL": 1.3159273651835084, "JANUVIA": 3.553495622279256, "KEPPRA": 1.3714205300686308, "NPLATE": 6.497698601778965, "PLAVIX": 2.1963222721546933}
\ No newline at end of file
+{"LYNPARZA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5759.json
index 6f158d7348b..d39aedad309 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5759.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5759.json
@@ -1 +1 @@
-{"ARANESP": 3.0546007557742643, "BYETTA": 3.55184204835388, "CICLOSPORIN": 2.062297079962748, "CLOPIDOGREL": 4.2148065615427885, "JANUVIA": 3.7727303207559895, "LEFLUNOMIDE": 13.671963942845345, "PEGINTRON": 3.962046917388971, "PLAVIX": 4.639052070488683, "ZOSTAVAX": 2.497668997278105, "null": 1.1637363769705638}
\ No newline at end of file
+{"ALEMTUZUMAB": 4.682436711751008, "CASPOFUNGIN": 10.15174630840824, "CICLOSPORIN": 4.176182759496952, "CLOPIDOGREL": 3.7706340923345367, "COMBIVIR": 11.704667221039369, "COMIRNATY": 0.1563856626463761, "DEXAMETHASONE": 5.221582265381327, "ELIQUIS": 2.128596603941256, "FASLODEX": 2.2539506872382327, "HUMALOG": 1.2160691477958, "KALETRA": 3.8726069375113, "KEPPRA": 1.6608712483827617, "LANTUS": 0.4960404246093386, "LEVETIRACETAM": 3.035015014493942, "NAGLAZYME": 48.25251103409794, "NOVOSEVEN": 12.765679601474098, "SPIKEVAX": 0.0958368776750856, "SPINRAZA": 37.80372092143507, "SYNAGIS": 7.379805371220383, "TEMOZOLOMIDE": 16.113104648133792, "VAXZEVRIA": 0.1751111896602741, "VOTRIENT": 1.5919376372842764, "null": 1.7413319187660856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/576.json
index 1cfb2d49633..3bcc367cb53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/576.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/576.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 9.825559097273809, "APROVEL": 3.871015095206571, "ARANESP": 171.87568015645115, "BINOCRIT": 172.36431590406747, "BUSULFAN": 3.1618252550748163, "CELLCEPT": 12.266874612439224, "CICLOSPORIN": 4.124159290574716, "COMBIVIR": 5.211683537367236, "DARBEPOETIN": 26.41592018628307, "EMTRIVA": 18.74988426690793, "EPOETIN": 210.8803792217742, "EXJADE": 1.3550021494853917, "IPILIMUMAB": 2.784467066528548, "KEYTRUDA": 1.0621533284436298, "LYRICA": 1.106624726894914, "MIRCERA": 245.8315059291889, "MYCOPHENOLATE": 9.399504414378557, "NEORECORMON": 473.508449493159, "OPDIVO": 1.144019940637858, "PEGASYS": 2.114870246685556, "PEGINTERFERON": 7.73264308463609, "PEGINTRON": 6.453376607821674, "RIBAVIRIN": 27.072688433532356, "TACROLIMUS": 9.435409341152765, "null": 1.1303225963906869}
\ No newline at end of file
+{"ADALIMUMAB": 1.9785319912704435, "AVASTIN": 14.871372989625067, "CABOMETYX": 7.978759359470787, "CIMZIA": 7.457756284708322, "COMIRNATY": 0.0587070022080474, "ENTYVIO": 37.91216443536936, "HUMIRA": 26.325392107690316, "NEXAVAR": 3.8626713946848215, "SIMPONI": 5.595216454595147, "STELARA": 25.78121449698306, "STIVARGA": 6.595486222015647, "SUTENT": 4.898771255917191, "null": 0.5329404636484212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5760.json
index dbb496a7d75..ccab937611d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5760.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5760.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 72.61635787511798}
\ No newline at end of file
+{"null": 0.578691898322137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5761.json
index fa9b53e911e..056e5b4282b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5761.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5761.json
@@ -1 +1 @@
-{"ASPARAGINASE": 731.7837258096637, "CICLOSPORIN": 15.598157148618046, "CYTARABINE": 23.799004635289663}
\ No newline at end of file
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5762.json
index 12400d023ce..fb7f53bf8b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5762.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5762.json
@@ -1 +1 @@
-{"KEPPRA": 7.3403523726244995, "null": 6.451996972234148}
\ No newline at end of file
+{"ABACAVIR": 1.1997564505452132, "AFINITOR": 2.3557079886584806, "ATEZOLIZUMAB": 26.313559263725868, "ATRIPLA": 2.0739018669978253, "AVASTIN": 5.97146761264325, "BEDAQUILINE": 4.571709955477257, "BEVACIZUMAB": 2.404461363534158, "BYETTA": 2.5738949700547136, "CELLCEPT": 6.168907889087056, "CICLOSPORIN": 4.093106386701189, "CIMZIA": 0.5016518182543548, "COMBIVIR": 10.746430210204553, "COMIRNATY": 0.0316986375986059, "CRIXIVAN": 74.3874413742463, "CYTARABINE": 2.346505604908505, "DOXORUBICIN": 5.047385593986239, "ELIQUIS": 0.7158382187255757, "ESOMEPRAZOLE": 22.71896492943059, "FASLODEX": 2.796452111200169, "FILGRASTIM": 10.957984356054409, "FORXIGA": 4.36820427325827, "FULVESTRANT": 3.8873554439439415, "IBRANCE": 1.3143542774947707, "JANUMET": 2.803399007887481, "JARDIANCE": 1.5366563752726676, "JEVTANA": 14.960358500526286, "KEPPRA": 1.1189292437084009, "KEYTRUDA": 4.033669715805142, "LEVETIRACETAM": 1.386409170816129, "LEVOFLOXACIN": 1.3979577795532756, "LONSURF": 5.704149244143079, "MYCOPHENOLATE": 4.2588562025797145, "NEULASTA": 3.3233207772963778, "NORVIR": 19.56728830786064, "OPDIVO": 1.7129186469322053, "PEMBROLIZUMAB": 3.826931012806324, "REYATAZ": 13.064552364159002, "SIMPONI": 0.8523644802592406, "SPIKEVAX": 0.0683454886861725, "STELARA": 0.953007446167801, "STIVARGA": 4.055185546224528, "STRIBILD": 1.6863972307176616, "SUTENT": 0.7417227622799814, "TOVIAZ": 6.592974148708766, "TRUVADA": 0.9375798166675748, "VOTRIENT": 2.05049387855742, "XOFIGO": 8.67912569056462, "XTANDI": 3.5142821980481207, "null": 0.8784361857421827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5763.json
index 0714cbe034c..24960b659ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5763.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5763.json
@@ -1 +1 @@
-{"HUMALOG": 2.330788457325879, "null": 1.6502606036047287}
\ No newline at end of file
+{"COMBIVIR": 36.51244653979159, "EFAVIRENZ": 112.44335762593488, "null": 2.5605666572279024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5764.json
index 914cb40f26f..9977cee8e6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5764.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5764.json
@@ -1 +1 @@
-{"null": 4.300975156186353}
\ No newline at end of file
+{"null": 0.800415278061176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5765.json
index 53d2df19ca5..ced6af6478a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5765.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5765.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.3687895092896931, "COMIRNATY": 2.265487973017836, "NIMENRIX": 8.053803198433927, "PRIVIGEN": 22.847411545135053, "SHINGRIX": 2.106848332491285, "SPIKEVAX": 1.0597843043555142, "VAXZEVRIA": 2.391493760990039, "ZYPREXA": 2.0007899326893392}
\ No newline at end of file
+{"IRESSA": 39.81332002725986, "MIDAZOLAM": 21.10657414664368, "SUTENT": 7.526402980153036, "null": 0.5746813363381259}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5766.json
index 88ce6fdf86e..b810b2f977d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5766.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5766.json
@@ -1 +1 @@
-{"KEYTRUDA": 5.223122764657142, "SUTENT": 3.58081522979573}
\ No newline at end of file
+{"CIMZIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5767.json
index 258957c0684..5684c3da855 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5767.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5767.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 2.6019176531375776, "CICLOSPORIN": 1.4182785422640898, "CYMBALTA": 1.5740457816233568, "FENTANYL": 3.4946520636026346, "GARDASIL": 2.010269425713638, "HUMIRA": 2.1876247276139984, "IBUPROFEN": 2.1040351789282403, "KALETRA": 2.1669977229298123, "KEPPRA": 2.15960321839786, "LACOSAMIDE": 16.354456111143946, "LEVETIRACETAM": 3.8141550270278377, "MIDAZOLAM": 18.00325735264516, "TWINRIX": 3.983724362663025, "VIMPAT": 7.102562501107253, "null": 2.839953917591586}
\ No newline at end of file
+{"null": 0.7694978515518868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5768.json
index 0cfdccd8a12..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5768.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5768.json
@@ -1 +1 @@
-{"ABATACEPT": 11.236654246463274, "ABILIFY": 33.18425407466267, "ADALIMUMAB": 7.523893958818003, "AMINOSALICYLIC": 2.858997403932905, "ANAKINRA": 7.672484533025304, "APIXABAN": 18.26453764316842, "APREMILAST": 6.346264408954157, "ARIPIPRAZOLE": 24.241186139837545, "BIKTARVY": 3.6439446922268695, "BYDUREON": 3.0532159669409067, "BYETTA": 1.9431017227512324, "CANAGLIFLOZIN": 19.6982147703357, "COSENTYX": 3.3587241289799405, "DAPAGLIFLOZIN": 17.28763761920976, "DULOXETINE": 1.7074122977271913, "ENBREL": 1.8542389883223536, "EXFORGE": 1.296149179494965, "FASENRA": 1.1219722980084048, "GLYCOPYRRONIUM": 66.4218957243778, "HUMALOG": 1.4804717922716637, "INVEGA": 38.05853944663191, "INVOKANA": 4.619202327250742, "IRON": 4.898398896577418, "JANUMET": 1.2744508479708518, "JANUVIA": 1.4642564100232485, "LATUDA": 4.261541041772467, "LYRICA": 2.047583306796765, "MEPOLIZUMAB": 1.640913461546859, "METHOTREXATE": 5.799859143616076, "OLANZAPINE": 5.668834166547385, "RISPERIDONE": 5.738143285086417, "TASIGNA": 1.8305157313903904, "TREMFYA": 1.5764781449509149, "TRULICITY": 1.2101192533087202, "ZOSTAVAX": 15.277143640395344, "ZYPREXA": 15.727893569764973}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5769.json
index d274ded2615..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5769.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5769.json
@@ -1 +1 @@
-{"ABACAVIR": 13.102626038528143, "BUSULFAN": 29.54317595540411, "CELLCEPT": 6.987507970683218, "CICLOSPORIN": 45.742529321595576, "ENBREL": 22.3294370278092}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/577.json
index a39afaa654b..90fada2f889 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/577.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/577.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 23.593529507529723, "ARANESP": 3.436135630868969, "ASPARAGINASE": 10.132184254094309, "BUSULFAN": 25.37713273505147, "CELLCEPT": 2.924830084720364, "CICLOSPORIN": 8.521443350858325, "COMBIVIR": 8.483671029155875, "CYTARABINE": 2.7634868926917022, "DARATUMUMAB": 23.13578027934807, "DOXORUBICIN": 4.956175486850026, "EXJADE": 8.908519567182362, "INCIVO": 4.699734438463656, "IPILIMUMAB": 2.486168795344502, "KEPPRA": 3.763056019836746, "NPLATE": 8.982684556704914, "PEGASYS": 4.636340723237672, "PEGINTERFERON": 7.197434266897775, "PEGINTRON": 1.198652180276116, "PLAVIX": 4.213671247983228, "REVOLADE": 156.66864436367123, "SOLIRIS": 25.90175120911438, "TAGRISSO": 2.4584023089024867, "TASIGNA": 2.09445202044265, "TEMODAL": 15.672726238864222, "TEMOZOLOMIDE": 42.15746161684291, "THIOTEPA": 16.247896771933043, "VFEND": 1.3661590118230038, "null": 1.5222812037048166}
\ No newline at end of file
+{"null": 0.9567157319567168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5770.json
index e0175031054..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5770.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5770.json
@@ -1 +1 @@
-{"ARSENIC": 438.63740015950617, "BRINTELLIX": 9.956686754305707, "CHAMPIX": 14.796793945329526, "CYMBALTA": 5.034058823718284, "DULOXETINE": 21.600923040193592, "KEPPRA": 3.8921821733887274, "LATUDA": 19.337806689170385, "OLANZAPINE": 6.924538703314073, "ZYPREXA": 9.106373952905454, "null": 2.237770939281953}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5771.json
index 8369fbd837b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5771.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5771.json
@@ -1 +1 @@
-{"ABILIFY": 73.19126478121633, "ARIPIPRAZOLE": 117.3795063365944, "AVAMYS": 4.975782922883751, "AZILECT": 46.797422012772095, "CHAMPIX": 2.287928930852209, "DULOXETINE": 5.97528600717863, "GARDASIL": 2.858695349858913, "KEPPRA": 2.485033408505231, "LATUDA": 4.327155416712492, "LEVETIRACETAM": 1.9728031751093449, "LEVODOPA": 14.00328034366333, "OLANZAPINE": 11.01658567352957, "SIFROL": 20.97054602236829, "XYREM": 5.763962290003075, "ZYPREXA": 4.350587210559445, "null": 1.8292165215811516}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5772.json
index 28d02462504..286802270a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5772.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5772.json
@@ -1 +1 @@
-{"null": 1.5251192380717895}
\ No newline at end of file
+{"PRIVIGEN": 898.8870729328216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5773.json
index 6efc476f7d1..d5baa90ddfd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5773.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5773.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 36.54650113837572, "OLANZAPINE": 47.47952688971287, "null": 1.611653283852084}
\ No newline at end of file
+{"null": 1.4683613789688683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5774.json
index 7f706c4adba..52ff73aaedc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5774.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5774.json
@@ -1 +1 @@
-{"null": 1.2695044214265356}
\ No newline at end of file
+{"BRINTELLIX": 1.5876533019547046, "CHAMPIX": 0.5687308918428627, "COMIRNATY": 2.1033970758229974, "CYMBALTA": 0.9577109871548298, "GARDASIL": 14.740686373023308, "KEPPRA": 1.0985817684615908, "MODERNA": 0.9211121735423056, "SPIKEVAX": 1.2617848332653312, "TOZINAMERAN": 2.655667849857364, "VAXZEVRIA": 1.768907837378051, "null": 0.8268218170141539}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5775.json
index dba7c55938d..9977cee8e6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5775.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5775.json
@@ -1 +1 @@
-{"ACLIDINIUM": 37.10626431864435, "ALENDRONATE": 652.4529975226078, "ANORO": 14.588579984397548, "APIXABAN": 58.36573228558085, "AVANDIA": 7.250883023933782, "AZATHIOPRINE": 8.068280361910475, "ELIQUIS": 3.5526240057503102, "HUMIRA": 7.703538013323878, "MEPOLIZUMAB": 13.535249459310538}
\ No newline at end of file
+{"null": 0.800415278061176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5776.json
index ef2662db8c4..e28b7a55454 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5776.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5776.json
@@ -1 +1 @@
-{"BYETTA": 31.22489130869108, "JANUVIA": 11.244190319169984, "null": 1.8384144459260363}
\ No newline at end of file
+{"ADALIMUMAB": 13.862187762210567, "null": 0.7443608579779352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5777.json
index 344883e263e..78a10d9dcdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5777.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5777.json
@@ -1 +1 @@
-{"ACLIDINIUM": 38.78514261709207, "ALENDRONATE": 78.8709776157945, "ANORO": 67.18526812791438, "APIXABAN": 17.47786672280041, "AVAMYS": 36.83179941451178, "AZATHIOPRINE": 4.070173335759971, "BENRALIZUMAB": 62.91169907953648, "BRIDION": 4.785719336500796, "BUDESONIDE": 36.60759271961302, "CANAGLIFLOZIN": 16.508213335505754, "CHOLESTAGEL": 55.82454169535375, "CLOPIDOGREL": 1.1474765698887637, "DAXAS": 81.25887567309145, "DUAKLIR": 145.00925102216425, "ENTRESTO": 1.2782841731346075, "ESOMEPRAZOLE": 2.097997070885026, "FASENRA": 3.967576993899162, "FENTANYL": 3.5871798139939344, "FLUTICASONE": 54.25864613570611, "GLYCOPYRRONIUM": 44.02344786435396, "HIZENTRA": 1.7588481510089014, "HYDROCORTISONE": 2.239139349366045, "IBUPROFEN": 2.25409525695472, "INCRUSE": 4.522496775053304, "INVOKANA": 3.8711505949287215, "IRBESARTAN": 2.5180717189263224, "JANUMET": 1.0678599277363323, "LIRAGLUTIDE": 152.46478997433735, "MEPOLIZUMAB": 33.70875074627306, "METHOTREXATE": 3.392206572951215, "NAGLAZYME": 5.273498934977887, "NUCALA": 28.894712606831565, "OMALIZUMAB": 23.182360764463414, "PANTOPRAZOLE": 6.994172432874352, "PREGABALIN": 6.287911342908376, "SYNAGIS": 3.121322617869412, "TRELEGY": 1.3060351280718296, "UMECLIDINIUM": 33.284421332421, "XOLAIR": 5.655817256685253}
\ No newline at end of file
+{"BEXTRA": 51.85667503452572, "COMIRNATY": 0.2839433572882319, "DEXAMETHASONE": 2.357837548403345, "GARDASIL": 0.7906255574425882, "LEVOFLOXACIN": 7.24966933145107, "MEPOLIZUMAB": 8.995472859381866, "MMRVAXPRO": 2.5325632893650285, "ONCASPAR": 46.04227133603601, "SPIKEVAX": 0.1769955958836291, "SUTENT": 0.6252925947214337, "TOZINAMERAN": 0.2054323421055991, "VAXZEVRIA": 0.2407435769327505, "null": 2.958901715436214}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5778.json
index 520dca42583..c4f19c30783 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5778.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5778.json
@@ -1 +1 @@
-{"BYETTA": 34.13640529153494, "JANUVIA": 12.98287556480673, "SAXENDA": 26.32632903703612, "SPIRONOLACTONE": 53.42267375952956, "TRULICITY": 16.89917769749009, "VICTOZA": 50.02272033820936}
\ No newline at end of file
+{"ABILIFY": 0.6061949752396757, "ALEMTUZUMAB": 1.507311053454252, "BOSULIF": 3.0743117283482606, "BUPIVACAINE": 7.907544864867567, "BUPRENORPHINE": 1.6706231574090014, "CAPECITABINE": 1.4383046157198858, "CHAMPIX": 0.3503969328107203, "COMIRNATY": 2.0136712549325075, "CYMBALTA": 0.6784270641669049, "DEXAMETHASONE": 1.327661390840318, "DULOXETINE": 2.757087954233844, "ELIQUIS": 0.4010284237777467, "ENBREL": 1.2778162387798613, "FENTANYL": 7.847009650464487, "GARDASIL": 2.4441828976645663, "IBRANCE": 0.3219967997819409, "INLYTA": 1.6118825743348677, "LENVIMA": 6.203625348806715, "METHOTREXATE": 1.071856775755038, "MMRVAXPRO": 0.5156125502288746, "MODERNA": 0.7966203141074212, "NEXAVAR": 0.7779017716245527, "QUTENZA": 7.613765454166288, "SHINGRIX": 10.070074794262313, "SPIKEVAX": 1.486825430048883, "STIVARGA": 1.270242682727134, "SUTENT": 2.6614116739016898, "TOZINAMERAN": 1.0571236369325494, "VAXZEVRIA": 1.5762047513071455, "XELJANZ": 0.370747828836062, "ZOSTAVAX": 0.4734039343411876, "null": 0.6423788017308226}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5779.json
index 0c2efce3376..0eabe45b525 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5779.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5779.json
@@ -1 +1 @@
-{"ABILIFY": 1.9618868303781216, "APIXABAN": 81.21641842899147, "BYDUREON": 3.998902086463563, "BYETTA": 7.292328161370191, "CHOLESTAGEL": 248.48900100341547, "CLOPIDOGREL": 2.3871152939624887, "CYMBALTA": 1.3462915464377416, "CYTARABINE": 2.724315726997285, "ELIQUIS": 1.3027415359184382, "IRBESARTAN": 34.4898290623038, "JANUMET": 7.483540892896189, "JANUVIA": 6.104547756404069, "MELATONIN": 13.340426662922388, "METHOTREXATE": 3.9948720926526544, "NAGLAZYME": 15.092124930041056, "SOMATROPIN": 93.44473712164935, "TESTOSTERONE": 27.36125663288645, "XYREM": 22.398941260294063, "ZOSTAVAX": 21.249320749623745, "ZYPREXA": 3.2927071125975385}
\ No newline at end of file
+{"AIMOVIG": 5.924323928203078, "COMIRNATY": 0.5583028219091329, "SPIKEVAX": 0.7505275059894655, "SUTENT": 2.502382853143841, "TOZINAMERAN": 1.4281288558726346, "VAXZEVRIA": 1.411801745849177, "null": 1.1072494686351797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/578.json
index 7df06d9d4c2..588b451b5eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/578.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/578.json
@@ -1 +1 @@
-{"BENZODIAZEPINE": 6.828105434603596, "BRIDION": 10.293039919551331, "BRILIQUE": 2.88808778465734, "BUPIVACAINE": 8.643477787121533, "BUPRENORPHINE": 1.296938851226206, "CICLOSPORIN": 1.2041858584826184, "CYTARABINE": 1.0013327365776603, "DULOXETINE": 5.05800065086327, "FENTANYL": 14.506630989042293, "HYDROCORTISONE": 5.681993997346934, "IBUPROFEN": 3.643004603410384, "INFANRIX": 42.26384642761485, "KEPPRA": 1.4856033922193672, "LEVETIRACETAM": 3.6717342005658433, "MIDAZOLAM": 16.42994024524625, "MMRVAXPRO": 4.161526218099412, "NAGLAZYME": 8.688030289211124, "NALOXONE": 69.22507979239305, "NOT": 2.2698479644444087, "OLANZAPINE": 1.1972627737998045, "PREVENAR": 19.58757845662804, "ROTATEQ": 14.852593495546712, "SOMATROPIN": 12.316305373243914, "SPINRAZA": 8.790394260314505, "SUFENTANIL": 3.863862385315131, "SYNAGIS": 57.086794905206126, "XYREM": 3.7164870615315473, "ZYPREXA": 1.229596942733189, "null": 2.998305437336556}
\ No newline at end of file
+{"CLOPIDOGREL": 3.812009074506384, "COMIRNATY": 0.2688922964520943, "ELIQUIS": 10.025145494913934, "INCIVO": 13.15985497548179, "LIXIANA": 21.132663684390533, "PEGASYS": 2.6022841428211843, "PEGINTERFERON": 6.423823976199437, "PLAVIX": 1.572581941439087, "SPIKEVAX": 0.2066835703013796, "SUTENT": 8.008286932459692, "TOZINAMERAN": 0.5664594198283459, "VAXZEVRIA": 0.6306677631863953, "null": 0.9662388161965796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5780.json
index 9a26eca1d2d..d6af4e7f5eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5780.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5780.json
@@ -1 +1 @@
-{"COMIRNATY": 2.074971587369053, "SHINGRIX": 6.811069586264487, "TOZINAMERAN": 3.0939438485057367, "ZOSTAVAX": 8.34938428033506}
\ No newline at end of file
+{"ALISKIREN": 202.6854615293846, "null": 1.8536962969900772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5781.json
index c785c37925a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5781.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5781.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 11.73133023751578, "COSENTYX": 8.706968915985879, "ELIQUIS": 18.33089033289348, "null": 1.510732927142325}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5782.json
index 9441005191e..20929791313 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5782.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5782.json
@@ -1 +1 @@
-{"ADCIRCA": 22.21482856195279, "ARANESP": 2.7448656331196544, "CLOPIDOGREL": 45.37271107912906, "ELIQUIS": 5.931428761155782, "ENOXAPARIN": 18.844602033886, "EXJADE": 4.245833867728391, "PLAVIX": 23.09045927506125, "ROTATEQ": 14.636764576177596, "TICAGRELOR": 35.740598372901744, "XARELTO": 9.944278996874278, "null": 1.0983000498845354}
\ No newline at end of file
+{"ARIPIPRAZOLE": 1.1481363337386123, "ASPARAGINASE": 8.296364388840908, "AVASTIN": 12.64358140586052, "BEVACIZUMAB": 2.0898157263847645, "BUSULFAN": 2.08932269352976, "COAPROVEL": 3.861494125388208, "CYTARABINE": 1.8001397617954318, "DEXAMETHASONE": 1.0354287690573034, "EXJADE": 2.4277984382224638, "FYCOMPA": 8.345077691863196, "IRINOTECAN": 7.326145207621402, "KEPPRA": 4.215939566476828, "LENVIMA": 11.82633170608136, "LEVETIRACETAM": 9.003340065181149, "MIRABEGRON": 30.185213718404963, "NEXAVAR": 3.817834493446929, "OLANZAPINE": 3.911850123361381, "ONCASPAR": 16.736105301556027, "PANITUMUMAB": 27.327104888389982, "PEGASYS": 0.939675933085939, "RISPERIDONE": 8.665817939994946, "STIRIPENTOL": 498.2714011121074, "STIVARGA": 4.869945673019456, "ZYPREXA": 1.0979555709928417, "null": 4.876356878904289}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5783.json
index f40ca8a23b0..68919de48f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5783.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5783.json
@@ -1 +1 @@
-{"null": 2.2796882444559303}
\ No newline at end of file
+{"ASPARAGINASE": 8.295920821338791, "BEVACIZUMAB": 7.957426675733114, "BOTULINUM": 15.99123185732148, "CAPECITABINE": 6.295420244631099, "IRINOTECAN": 12.268659875385437, "LEVETIRACETAM": 14.164951703507915, "OLANZAPINE": 6.6482093421491495, "null": 6.515496373234137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5784.json
index 5d337c5758d..d1c3b70b313 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5784.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5784.json
@@ -1 +1 @@
-{"QUTENZA": 1538.1797386052046, "ZOSTAVAX": 3.232285161238911, "null": 1.8345736828549328}
\ No newline at end of file
+{"KEYTRUDA": 4.407495560311134, "NEXAVAR": 18.404690150414865, "null": 1.14949061858642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5785.json
index 1faa32cbac6..d7fa7cc9451 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5785.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5785.json
@@ -1 +1 @@
-{"AVAMYS": 2.23193110671591, "BEOVU": 18.85339119830556, "COMIRNATY": 1.8917891379636729, "COSENTYX": 1.6690658310527158, "CYMBALTA": 4.1623066600193, "EYLEA": 11.369010583106714, "IKERVIS": 33.26831969137706, "KAFTRIO": 2.4273492309064038, "MEPOLIZUMAB": 14.676213678293555, "NEVANAC": 19.42386459040564, "NUCALA": 4.527092618176862, "SPIKEVAX": 1.6876350254919332, "TOZINAMERAN": 1.3155904738460849, "VAXZEVRIA": 2.284555869215628, "VIAGRA": 1.5140359606051352}
\ No newline at end of file
+{"EMTRICITABINE": 593.189358975067, "null": 0.4275639626801554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5786.json
index 58325bfe606..f26391efb65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5786.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5786.json
@@ -1 +1 @@
-{"BEOVU": 37.57471454772128, "BRIMONIDINE": 30.48440017252974, "BROLUCIZUMAB": 62.23780902167999, "COSENTYX": 1.7515571307251183, "DEXAMETHASONE": 1.2827788228395565, "EXFORGE": 1.445698266822597, "EYLEA": 16.473275989170876, "FLUTICASONE": 5.454881647425919, "HYDROCORTISONE": 1.0478197693124267, "IKERVIS": 83.92988741684864, "IRBESARTAN": 1.3588079402220776, "JETREA": 13.713770737041854, "MEKINIST": 1.370677989096436, "MELATONIN": 1.5528896810607626, "MEPOLIZUMAB": 6.117970676065559, "MMRVAXPRO": 1.037642973368995, "NEPAFENAC": 52.03467092134263, "NEVANAC": 36.290202634937856, "NIMENRIX": 1.0362348213245964, "NUCALA": 2.01306028874568, "OMALIZUMAB": 1.3961084233317211, "OPATANOL": 43.74035806725436, "RINVOQ": 1.0278172358680564, "RITUXIMAB": 1.1136426535637731, "SHINGRIX": 1.168340441854934, "SILDENAFIL": 1.108629141505562, "TAMIFLU": 1.8254463987836704, "TOBRAMYCIN": 6.195404658368457, "TOZINAMERAN": 1.383520137321959, "TRELEGY": 1.2680750816289172, "VIAGRA": 2.5504874357382774, "XOLAIR": 1.048145272635969, "ZELBORAF": 2.432905770960995, "null": 1.7726873479833545}
\ No newline at end of file
+{"ABACAVIR": 2.189000727463703, "AFINITOR": 0.3604636507588469, "AMIKACIN": 4.180003636970371, "AMINOSALICYLIC": 1.277485044263665, "ARAVA": 0.1143341533760143, "ASPARAGINASE": 9.86978245559182, "ATAZANAVIR": 38.13914183583642, "ATOSIBAN": 11.585104554602909, "AVASTIN": 1.3341860717860134, "AYVAKYT": 81.21165448975894, "AZACITIDINE": 2.2584543690588026, "BEDAQUILINE": 4.010835628548893, "BEVACIZUMAB": 3.191516553236521, "BIKTARVY": 1.7139769274036476, "BUSULFAN": 3.875019812757828, "CANCIDAS": 15.619777262057577, "CAPECITABINE": 2.60241979086696, "CASPOFUNGIN": 6.6184060113658045, "CELLCEPT": 1.0835163295265262, "CICLOSPORIN": 2.3714801729452257, "CLADRIBINE": 5.3307654304797305, "CLOFARABINE": 12.53120197398825, "COMBIVIR": 9.644926517629614, "COMIRNATY": 0.0233052373334721, "CRIXIVAN": 21.636897229342207, "CUBICIN": 2.780444514671022, "CYTARABINE": 8.00340091620727, "DAKLINZA": 16.030729118149914, "DEXAMETHASONE": 2.5252953130247047, "ELIQUIS": 0.1696421944037841, "EMTRICITABINE": 8.678625914807302, "ENOXAPARIN": 2.463234989475409, "EPIVIR": 8.815671634720543, "EXJADE": 3.5911029552396547, "EXVIERA": 72.20944292212168, "GARDASIL": 0.1956274592815403, "HALAVEN": 2.5689827564013554, "HARVONI": 4.510867606832952, "HERCEPTIN": 1.6217815496522476, "IBUPROFEN": 1.4883461190523284, "INCIVO": 2.2880024339723497, "INDINAVIR": 15.098558188528974, "IPILIMUMAB": 1.2120126076834157, "IRINOTECAN": 1.884747432237242, "ISENTRESS": 7.198116353770423, "JANUMET": 0.735977810310855, "JANUVIA": 1.063150919044834, "KAFTRIO": 14.285295902701291, "KALETRA": 11.240961552227372, "KEPPRA": 0.2556223637955362, "KEYTRUDA": 0.4737382774821994, "KISQALI": 1.706777479332821, "KIVEXA": 18.051900573636303, "KYMRIAH": 1.2520793224073157, "LACOSAMIDE": 2.737058832351046, "LAMIVUDINE": 3.627244885292161, "LEVETIRACETAM": 0.7168737156306466, "LEVOFLOXACIN": 0.880614213254714, "LITAK": 45.972828608775394, "LONSURF": 2.556312633099909, "MERCAPTOPURINE": 5.757687995917776, "METHOTREXATE": 1.7324341598282598, "MIDAZOLAM": 1.3582612356202437, "NEXAVAR": 4.206334954951767, "NILOTINIB": 13.603184943644372, "NORVIR": 42.8540899561524, "NOXAFIL": 12.02073830328612, "OCALIVA": 7.373711556774623, "OFEV": 0.9492003859258616, "OLYSIO": 61.468550347275226, "ONCASPAR": 9.594333350376742, "OPSUMIT": 0.8957083867814183, "PAZOPANIB": 8.237906255736153, "PEGASYS": 1.6404982371994563, "PEGINTERFERON": 4.504520115829125, "PEGINTRON": 1.870137747155411, "PLAVIX": 0.7639292418336494, "POSACONAZOLE": 5.946134570743815, "PROPRANOLOL": 5.228812366552086, "REBETOL": 8.776697948270735, "REYATAZ": 98.03927409503956, "RIBAVIRIN": 9.310040241056877, "ROACTEMRA": 0.6786562097641946, "SIMEPREVIR": 37.07307716573468, "SOLIRIS": 1.0952266935533743, "SOVALDI": 19.273544181611605, "SPIKEVAX": 0.0230549222510319, "STIVARGA": 8.973271325476142, "SUTENT": 0.8782404770423876, "TAMIFLU": 1.1493113617497743, "TASIGNA": 7.652951687792893, "TRUVADA": 0.1238367383409933, "VFEND": 2.196505667397472, "VORICONAZOLE": 1.8600283585809296, "VOTRIENT": 4.75756366774999, "XELODA": 3.171059135469399, "YESCARTA": 3.793739634463942, "ZELBORAF": 2.8194306687265214, "ZYPREXA": 0.450379311843727, "null": 1.0870675275370678}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5787.json
index b48225e1b9d..08e8d8ebefe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5787.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5787.json
@@ -1 +1 @@
-{"EYLEA": 86.21309615490061, "ZOSTAVAX": 4.581015030890859, "null": 1.366770569685885}
\ No newline at end of file
+{"LANTUS": 5.982948142146345, "SUBOXONE": 16.185445036888865, "null": 1.651722718256705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5788.json
index d621a866c27..36c0c2aaf63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5788.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5788.json
@@ -1 +1 @@
-{"ATAZANAVIR": 11.090474091391656, "BUPRENORPHINE": 1.9791883412346143, "CYMBALTA": 1.393955828143651, "EXJADE": 4.793531916887997, "EXVIERA": 14.675267961757802, "LEVOFLOXACIN": 2.935330170742204, "NEXAVAR": 3.0906704393524307, "NORVIR": 41.01902061840364, "OCALIVA": 16.88078745165721, "OPTIMARK": 8.606465085381101, "PEGASYS": 1.0436888665296575, "REYATAZ": 162.10864387129527, "SOLIRIS": 3.6767950684675497, "STIVARGA": 8.2514143042709, "SUBOXONE": 2.544180016405388, "SUTENT": 1.3976271983410602, "TRACLEER": 3.8830844366291073, "TWINRIX": 7.527489952226493, "null": 1.8246181431113475}
\ No newline at end of file
+{"ABATACEPT": 3.2426618220390004, "ADALIMUMAB": 3.883396605955818, "AFINITOR": 1.3366103332471362, "APREMILAST": 16.766447692907377, "ARANESP": 0.7589684264714465, "ARAVA": 0.7997979970206429, "AZATHIOPRINE": 2.5108634619292247, "BIKTARVY": 7.541415654461298, "BONVIVA": 10.33021937226971, "BORTEZOMIB": 7.89263979461127, "BUSULFAN": 1.9980671278743372, "BYETTA": 1.8795497865227455, "CANCIDAS": 6.249907200072996, "CELECOXIB": 4.4704417593419885, "CELLCEPT": 1.8416785684280783, "CICLOSPORIN": 1.8041528187585527, "CIMZIA": 0.2286270884165496, "CINACALCET": 74.16233246502723, "COAPROVEL": 3.5365104278351827, "COMIRNATY": 0.0246309491057264, "CYMBALTA": 0.2073638594830783, "CYTARABINE": 1.263644530978995, "DARZALEX": 2.348415920305669, "DASATINIB": 6.843970899264061, "DENOSUMAB": 5.607487301895458, "DEXAMETHASONE": 1.7491161495985963, "ELIQUIS": 0.2098759366778042, "ENBREL": 14.239782167196635, "EVENITY": 8.224792986348008, "EVISTA": 3.031063779175513, "EXFORGE": 0.9921068048682858, "FASLODEX": 2.268550552941494, "FORSTEO": 28.35482959898496, "HUMIRA": 0.647318892709184, "HYDROXOCOBALAMIN": 408.7547512422973, "IBRANCE": 1.077906490527626, "INLYTA": 2.340213581533172, "IPILIMUMAB": 1.6978739170050294, "IRBESARTAN": 3.228570718867339, "JANUVIA": 0.5831374308026613, "JARDIANCE": 0.4649311375438716, "KEPPRA": 0.4697750430795507, "KEYTRUDA": 1.7443039434007048, "KYPROLIS": 4.883966232416806, "LENVIMA": 2.2987456275342466, "MEKINIST": 1.0114813779953238, "MIMPARA": 58.74948521661065, "MOVYMIA": 21.41948279786065, "NEXAVAR": 0.3686079187120897, "OLANZAPINE": 0.9319490289946846, "OPDIVO": 2.2228626430324225, "PANTOPRAZOLE": 3.462389643437967, "PEGASYS": 0.3639370122065585, "PEGINTERFERON": 1.662832818651434, "PEGINTRON": 0.4335193406565014, "POTELIGEO": 18.129281781054377, "PREOTACT": 273.23643781903644, "REVLIMID": 4.229150284990906, "SUTENT": 1.1575021447258007, "TELMISARTAN": 8.75568038213015, "TERIPARATIDE": 76.67013068304536, "TORISEL": 3.94342967994974, "TRUVADA": 0.2275827729022762, "VELTASSA": 3.483191689112846, "VENCLYXTO": 5.942842772370103, "VENETOCLAX": 4.06566124306363, "VFEND": 0.8239055433701129, "VORICONAZOLE": 3.7060830466172767, "VOTRIENT": 0.7671624088410522, "XTANDI": 0.7775978026548177, "ZOLEDRONIC": 39.44529671253941, "ZOSTAVAX": 0.5857437396056603, "ZYPREXA": 0.4649922244294926, "null": 1.4756037441170833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5789.json
index 5ed686d3417..ff225af61de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5789.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5789.json
@@ -1 +1 @@
-{"null": 1.0067924667284014}
\ No newline at end of file
+{"null": 0.3643902650883761}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/579.json
index 54dfd143433..0d535da3b52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/579.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/579.json
@@ -1 +1 @@
-{"FENTANYL": 16.41262609313192, "LEVETIRACETAM": 14.029602172204472, "MIDAZOLAM": 29.364445466068627, "SYNAGIS": 53.88703751774717, "null": 1.70092310324581}
\ No newline at end of file
+{"AFINITOR": 1.3966598579867708, "AIMOVIG": 0.6782724939700816, "AUBAGIO": 4.843845471241635, "BENLYSTA": 1.2239470231947114, "BUPIVACAINE": 8.942581474406607, "CIMZIA": 0.5229737829987595, "CLOPIDOGREL": 1.2822528655045555, "COMIRNATY": 0.2207964009792433, "CYMBALTA": 0.8559558917269009, "CYTARABINE": 1.0274208660870396, "ELIQUIS": 0.626879618098958, "ENTYVIO": 4.067658519168047, "GARDASIL": 1.185780802637925, "HUMALOG": 0.5791237438638596, "HUMIRA": 3.465806971446582, "IBRANCE": 0.6612977730765607, "INFLIXIMAB": 6.970024780586294, "INSULIN": 1.3464486210362925, "JANUVIA": 1.2140541589130125, "JARDIANCE": 0.7576600806217657, "KEPPRA": 1.495173143326947, "KEYTRUDA": 0.3861127916881436, "LANTUS": 0.2797544620433848, "LYRICA": 1.2528090131060516, "MEMANTINE": 19.12740493642513, "METHOTREXATE": 1.1617944728966092, "OCEAN": 143.4849730525466, "OFEV": 2.206531905684396, "OLANZAPINE": 1.7262254830495147, "PEGASYS": 1.012075206327277, "PLAVIX": 1.3365231702412108, "SPIKEVAX": 0.2964514972947349, "SUTENT": 1.0781489192281235, "TOVIAZ": 2.86666338473011, "TOZINAMERAN": 0.6600079938005975, "VAXZEVRIA": 0.2506241084678886, "VFEND": 1.2217016318357967, "XELJANZ": 1.1505673095996216, "XTANDI": 1.7494246013582335, "ZOSTAVAX": 0.5847286478821403, "ZYPREXA": 1.6981942105465797, "null": 2.0191216479908816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5790.json
index 33bbeb26090..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5790.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5790.json
@@ -1 +1 @@
-{"COMIRNATY": 1.5727980240642414, "KEYTRUDA": 11.793309206194769, "PEMBROLIZUMAB": 45.98025625679719}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5791.json
index bb5bdf448bb..e263ecf43bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5791.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5791.json
@@ -1 +1 @@
-{"null": 1.0924667414613298}
\ No newline at end of file
+{"FORSTEO": 39.98048944320949, "null": 2.609398343587493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5792.json
index 2260fd9b341..a0777814b29 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5792.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5792.json
@@ -1 +1 @@
-{"EYLEA": 610.6207487368232}
\ No newline at end of file
+{"ACLIDINIUM": 87.65943224161082, "ARIPIPRAZOLE": 4.558119517834448, "BUPRENORPHINE": 2.857476730171905, "CASPOFUNGIN": 19.25129509686071, "CICLOSPORIN": 1.0492017681667758, "CLOPIDOGREL": 1.406249837828738, "COMIRNATY": 0.0986752354256139, "DEXAMETHASONE": 2.492895469261716, "FENTANYL": 18.24151674555093, "HYDROCORTISONE": 10.323423269446415, "KEYTRUDA": 1.1813654251748456, "LEVETIRACETAM": 3.568336968158876, "MIDAZOLAM": 25.766973629773883, "NORVIR": 12.482923692416897, "OPSUMIT": 4.3349815533207385, "PREGABALIN": 8.011447575436026, "REVATIO": 7.790111372883434, "SPIKEVAX": 0.1531892576540217, "ZYPREXA": 4.593318771609615, "null": 1.9698071285494296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5793.json
index c613a886e9e..444639dcc7e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5793.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5793.json
@@ -1 +1 @@
-{"null": 1.272362384048146}
\ No newline at end of file
+{"null": 3.241696835702917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5794.json
index 7c48730bc64..5964ec2bdf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5794.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5794.json
@@ -1 +1 @@
-{"ARAVA": 3.661620326929036, "BELANTAMAB": 2921.8518615322105, "COTELLIC": 93.4614007033173}
\ No newline at end of file
+{"EVISTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5795.json
index 80e4058d30b..22b91a9ec19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5795.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5795.json
@@ -1 +1 @@
-{"CYMBALTA": 3.61198627754864, "LANTUS": 3.7212808106720168, "PEGASYS": 3.534021348166976, "SUTENT": 2.769495280217558, "TOZINAMERAN": 4.101983273283674, "VIAGRA": 28.872690648385948}
\ No newline at end of file
+{"null": 3.6151999885120047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5796.json
index 69867a88679..974a5479ca2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5796.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5796.json
@@ -1 +1 @@
-{"BEOVU": 577.9275414880514, "EYLEA": 90.79550693576324}
\ No newline at end of file
+{"COMIRNATY": 0.116615130990339, "ESBRIET": 9.08254707134164, "IBRANCE": 2.458199557668983, "JANUMET": 9.33397085750518, "SAXENDA": 9.95746035965688, "SUTENT": 16.613239145022153, "TOZINAMERAN": 0.6629772082330841, "null": 1.2659081041725515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5797.json
index 71ff512b168..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5797.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5797.json
@@ -1 +1 @@
-{"null": 2.762913163152542}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5798.json
index db70bd694f4..bff14695bb2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5798.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5798.json
@@ -1 +1 @@
-{"ABILIFY": 28.628464108084536, "ARIPIPRAZOLE": 20.9825861799108, "INVEGA": 29.95337294481709, "LATUDA": 89.56453064257155, "OLANZAPINE": 25.772206569072985, "ZYPREXA": 8.815602300199465, "null": 3.363162173696292}
\ No newline at end of file
+{"ABACAVIR": 2.5043014690160077, "ABATACEPT": 21.10372963586569, "ADALIMUMAB": 8.361652525353406, "AFINITOR": 4.3826182998012735, "APREMILAST": 3.1427390531804567, "ARAVA": 4.321216691001969, "ARIPIPRAZOLE": 1.9531261758052056, "ATAZANAVIR": 2.438544567228293, "ATRIPLA": 0.2414467800028457, "AVANDIA": 1.8982446268386932, "BIKTARVY": 2.1680425463694517, "BYDUREON": 2.34979686121558, "BYETTA": 9.085032833508189, "CAPECITABINE": 4.288158325527211, "CELLCEPT": 1.7853571983176049, "CERTOLIZUMAB": 29.157764496522365, "CICLOSPORIN": 1.564313655358469, "CIMZIA": 1.4090129525569486, "CLOPIDOGREL": 0.5731982655811994, "COMBIVIR": 4.236795279306797, "COMIRNATY": 0.1397627633773134, "COSENTYX": 0.4934919157572547, "CRIXIVAN": 21.435091590214903, "ELIQUIS": 0.2106732606613088, "EMTRIVA": 24.183076725052317, "ENBREL": 3.9040582303196114, "EPIVIR": 14.79790248279143, "EXFORGE": 1.4118770359941175, "FASLODEX": 1.0770453236959168, "FORSTEO": 0.9946295749559116, "GENVOYA": 11.364104759277613, "GLYCOPYRRONIUM": 80.32487096122237, "HUMALOG": 0.5592869102231186, "HYDROCORTISONE": 2.2566574133524604, "IBRANCE": 0.3370432101215478, "INTELENCE": 20.331408852927524, "INVIRASE": 29.71684111750704, "JAKAVI": 1.72446851532169, "JANUMET": 6.739832439922782, "JANUVIA": 5.513922783639032, "KALETRA": 4.609593855989078, "KEPPRA": 0.3551822732067006, "LAMIVUDINE": 10.348829177875848, "LANTUS": 0.3864852648043368, "MEPOLIZUMAB": 1.043098103803045, "MIRABEGRON": 17.775597585053816, "MYCOPHENOLATE": 2.7622384369120505, "NILOTINIB": 10.103422689135725, "NORVIR": 3.832174146612736, "OLANZAPINE": 1.840745289889763, "ONCASPAR": 4.941555833393443, "PANTOPRAZOLE": 2.140794171881774, "PLAVIX": 0.5675023605850875, "RINVOQ": 5.589889432036182, "ROACTEMRA": 12.078209236971054, "SPIKEVAX": 0.0438579144378762, "STELARA": 0.4400648339379405, "STIVARGA": 0.8621305880749266, "SUTENT": 0.3789326110822834, "SYMTUZA": 53.33628903283755, "TASIGNA": 9.74040015134888, "TOCILIZUMAB": 6.720206429157618, "VAXZEVRIA": 0.0143591996131531, "VIAGRA": 0.8488130277735435, "XELJANZ": 0.4650985097128792, "ZOSTAVAX": 5.683785848749014, "ZYPREXA": 8.911636697864235, "null": 0.5566790496717581}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5799.json
index 287537b3ef0..2282dd284d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5799.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5799.json
@@ -1 +1 @@
-{"null": 4.644398536330027}
\ No newline at end of file
+{"COMBIVIR": 185.9864470141101, "null": 0.3476500171942541}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/58.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/58.json
index 6a3d8d191a5..b1f80b87816 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/58.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/58.json
@@ -1 +1 @@
-{"CIMZIA": 10.632784878283328, "ENTYVIO": 34.78200113140713, "STELARA": 11.700579230958237}
\ No newline at end of file
+{"ACETYLSALICYLIC": 176.27066865559016, "ARAVA": 1.3861485243835197, "BUDESONIDE": 0.8954468820711069, "BUPIVACAINE": 7.007363655143908, "BYETTA": 7.326786308921675, "CLOPIDOGREL": 0.8507139579866273, "COMIRNATY": 0.5116116990192437, "ELIQUIS": 1.4855790778843032, "EMPAGLIFLOZIN": 8.097988738803862, "ESBRIET": 3.40542994981012, "FORXIGA": 2.318804580895704, "GARDASIL": 2.2635609413244744, "INVOKANA": 10.850415787038829, "JANUMET": 7.076779415434595, "JANUVIA": 3.907935796149604, "JARDIANCE": 4.800938010709016, "KEYTRUDA": 1.2041167777267423, "NEXAVAR": 2.884630197055093, "OFEV": 9.189783815760324, "PEGASYS": 0.5610487786980918, "PEGINTRON": 1.547329567613987, "SIMPONI": 2.03435866918208, "SPIKEVAX": 0.3980913784648294, "STELARA": 1.1818733327335924, "TOZINAMERAN": 0.6735932668920864, "VAXZEVRIA": 0.4933776799639005, "XARELTO": 8.345556497234348, "ZOSTAVAX": 2.593697544139217, "null": 1.1549409241325648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/580.json
index 76fb44802f5..804a36154e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/580.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/580.json
@@ -1 +1 @@
-{"ANAKINRA": 699.1225933891851, "ENBREL": 6.305589108307958, "I": 3002.8779500427586}
\ No newline at end of file
+{"null": 0.3425776569616238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5800.json
index fca0b5e82d5..1c170470223 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5800.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5800.json
@@ -1 +1 @@
-{"AFINITOR": 1.2553277426996616, "ALEMTUZUMAB": 5.735476573627094, "COMIRNATY": 1.8079624375440777, "COSENTYX": 1.0587553633051987, "CYTARABINE": 1.627094622214856, "DEXAMETHASONE": 1.3677644770878905, "ENTRESTO": 1.053203578563098, "IMATINIB": 9.137249758967762, "MEPOLIZUMAB": 1.389995855493356, "NEXAVAR": 1.6656719671295566, "STIVARGA": 1.9806146176672623, "SUTENT": 1.7522131815800863, "TASIGNA": 1.9225439514726168, "TOZINAMERAN": 2.681374666284752, "VAXZEVRIA": 1.114142230780696, "XALKORI": 3.7569855983701848}
\ No newline at end of file
+{"COMIRNATY": 0.3497959993870891, "ELIQUIS": 4.3192529935927695, "HUMALOG": 2.9039004406859408, "SPIKEVAX": 0.2917498040890724, "TOZINAMERAN": 0.4255298374646308, "VAXZEVRIA": 0.7055502318060815, "null": 1.018706942168642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5801.json
index a1bb2051a49..5b80769f5e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5801.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5801.json
@@ -1 +1 @@
-{"ACTOS": 4.965627294272026, "ADALIMUMAB": 1.923379024322169, "ADCIRCA": 4.344012397501819, "ADEMPAS": 5.30380729086785, "AERIUS": 1.3490224803568809, "AFINITOR": 2.3228574040088965, "ALIMTA": 1.6564331694455512, "AMBRISENTAN": 4.846218519886903, "AMGEVITA": 17.355048168592948, "APROVEL": 1.067455924060393, "AVANDAMET": 2.3627474756270748, "AVANDIA": 5.649473610403978, "BEDAQUILINE": 1.1607565956339865, "BONVIVA": 1.9743059185318488, "BOSULIF": 1.1033639533196782, "BRIDION": 1.3915088642654847, "CABOMETYX": 1.305282619599755, "CANCIDAS": 2.1624607701070646, "CELECOXIB": 1.1734682680010622, "CELSENTRI": 2.5430580199616366, "CICLOSPORIN": 1.3254797315450129, "COMBIVIR": 1.7273934848464008, "COMPLEMENT": 12.91950466584628, "CONTRAST": 5.161057756807073, "COSENTYX": 1.9226364048231432, "COTELLIC": 1.7978749438012844, "DAPAGLIFLOZIN": 1.493519260476019, "DASATINIB": 1.5956224175837843, "DESLORATADINE": 2.050463468575645, "DEXAMETHASONE": 1.0686195654688848, "DOCETAXEL": 1.1982015578606011, "EFAVIRENZ": 1.0089311017560432, "EMPAGLIFLOZIN": 1.2316934256309686, "ENOXAPARIN": 1.143628706275991, "ENTRESTO": 3.962296584273642, "ERLEADA": 1.4299315343974164, "EUCREAS": 1.0720755613102189, "EXFORGE": 3.399053281214611, "EXJADE": 1.529078088708057, "EXVIERA": 2.3626370500136225, "FASLODEX": 1.000033636580551, "FENTANYL": 1.1257073103248596, "FLUTICASONE": 2.179725971660956, "GALVUS": 1.992006712418644, "GLIVEC": 7.841440942489659, "HALAVEN": 1.6407886100888458, "HERCEPTIN": 1.1179748000260523, "HYDROCORTISONE": 2.6393992151435755, "HYQVIA": 1.888998053005256, "IMATINIB": 3.0447025153450173, "IMIQUIMOD": 8.075763175232542, "INCIVO": 2.2834940836454782, "INFLIXIMAB": 1.6019108428567632, "INSULIN": 1.259052393194317, "IRON": 1.008628180406804, "JAKAVI": 1.216357782667787, "KEYTRUDA": 1.0904906834187256, "LAMIVUDINE": 2.3110925618244105, "LENVIMA": 2.619798012002812, "LEVOFLOXACIN": 1.4359275797100184, "LIXIANA": 1.0403382538518615, "LUPKYNIS": 3.124616948541081, "LYRICA": 1.959132978201079, "MACITENTAN": 2.36331364297496, "MEKINIST": 1.7386721570084676, "MELATONIN": 1.393730160773336, "MENVEO": 3.577665911248734, "MICARDIS": 1.5134560075996406, "MULTAQ": 3.054920461652236, "NEVIRAPINE": 1.522970013492774, "NEXAVAR": 1.2146009173272767, "NILOTINIB": 1.1601899385414116, "NORVIR": 2.0137407408963885, "NOT": 1.2009852469450455, "OLANZAPINE": 1.0520423997522894, "OMALIZUMAB": 9.524840635649024, "ONCASPAR": 1.7781172511634862, "OPSUMIT": 6.015809866413793, "OPTIMARK": 2.9731341476076505, "PAZOPANIB": 1.0299932979256663, "PEMETREXED": 1.3678686139143434, "QARZIBA": 3.238606306832298, "QUTENZA": 1.6851006923012957, "RADIATION": 3.7102596845300617, "RANEXA": 1.7865904060429094, "RAPAMUNE": 2.9596863816580017, "RASILEZ": 4.357158260730562, "REBETOL": 1.1674281337187211, "REVATIO": 3.528551314326556, "REVLIMID": 1.0760313328067406, "REYATAZ": 1.0074882274165398, "RITUXIMAB": 2.6931213804520997, "ROACTEMRA": 1.422391344871645, "ROSIGLITAZONE": 4.548903594873108, "RUXOLITINIB": 1.1800485031942003, "SIFROL": 1.870174305183653, "SILDENAFIL": 4.0061419508836895, "SOVALDI": 1.008164358446961, "SPIRONOLACTONE": 1.5609582271270088, "SPRYCEL": 2.8288642460091658, "STEROIDS": 5.473815044901856, "SUTENT": 1.6553389573988997, "TASIGNA": 1.6965535599711807, "TAXOTERE": 3.1204572923275715, "TEMOZOLOMIDE": 1.6426557314134995, "THALIDOMIDE": 2.486531273173087, "TORISEL": 1.8133834213149147, "TRACLEER": 4.875915566124861, "VALSARTAN": 3.3354315962276613, "VOTRIENT": 1.101613907164732, "XALKORI": 6.1516870180396825, "XOLAIR": 1.0766733584438766, "ZELBORAF": 1.5030322378114196, "ZIAGEN": 3.284761378562467, "ZYPREXA": 1.4175747972410686, "null": 1.3995811117821826}
\ No newline at end of file
+{"TRUVADA": 4.9373847004101705, "null": 1.0516534016431185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5802.json
index d8fef1f2e33..b52704dcd83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5802.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5802.json
@@ -1 +1 @@
-{"null": 1.0844206131302538}
\ No newline at end of file
+{"PEMETREXED": 55.48299098868674, "SUTENT": 2.93812170040978, "null": 1.229508264867212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5803.json
index 40ee18fc8bd..5256a4147c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5803.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5803.json
@@ -1 +1 @@
-{"JARDIANCE": 8.814384670206216, "null": 2.323994115839095}
\ No newline at end of file
+{"FENTANYL": 25.316982732339696, "null": 1.992354119715068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5804.json
index 383424d4b23..f49e0edd743 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5804.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5804.json
@@ -1 +1 @@
-{"null": 19.54644672009796}
\ No newline at end of file
+{"BIKTARVY": 47.90612869601023, "null": 1.001406191400178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5805.json
index 2d1c004a639..a4e1a18588e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5805.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5805.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.8381632224878064, "null": 2.8637850970169896}
\ No newline at end of file
+{"COMIRNATY": 0.4121833166140017, "NUCALA": 21.39584069217388, "null": 1.032593844914968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5806.json
index a76a7eec579..30380b6ee3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5806.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5806.json
@@ -1 +1 @@
-{"null": 2.5907254632306738}
\ No newline at end of file
+{"null": 1.719128601799418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5807.json
index 0e021cbc1a0..08e1beb5b3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5807.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5807.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.8708380996491647, "ACE": 4.287485847828577, "ACLIDINIUM": 5.260170690109287, "ACTOS": 3.845394188213933, "ADCIRCA": 2.731984846024386, "ADEMPAS": 4.5402496842493125, "ADENURIC": 2.746627518993653, "AFINITOR": 3.292260042409957, "ALIMTA": 2.9470339843375943, "ALISKIREN": 6.311166401519785, "ALPELISIB": 1.5895206062956408, "AMBRISENTAN": 5.576157889574819, "APROVEL": 2.093100989706836, "AVANDIA": 3.0749932058921328, "AZILECT": 3.240014114926104, "BETAFERON": 1.0876569765727395, "BETMIGA": 2.130477826037653, "BOCEPREVIR": 2.395237920595602, "BONVIVA": 1.2419568363185252, "BOSENTAN": 1.2928464230281025, "BOSUTINIB": 1.7430436524467967, "BUDESONIDE": 1.5023307882242878, "BUMETANIDE": 4.564941762235514, "BUPIVACAINE": 1.0504919029480977, "BUVIDAL": 2.725482452977497, "CABAZITAXEL": 1.4579797425326284, "CABOMETYX": 1.1172455915128965, "CARBIDOPA": 2.133083330380152, "CELECOXIB": 1.0272678568884186, "CELSENTRI": 2.027070091307062, "CLOPIDOGREL": 1.2223834627264143, "COAPROVEL": 2.6262445763556563, "COLLAGENASE": 33.285720701347, "CONTRAST": 9.477298474729473, "COPALIA": 11.175338583637824, "COTELLIC": 1.6500122553508458, "CRIXIVAN": 1.0678079108957803, "CRIZOTINIB": 4.112857174936864, "DAFIRO": 6.525972831883817, "DAPAGLIFLOZIN": 5.058925727791796, "DECITABINE": 3.350266980608194, "DEXAMETHASONE": 1.155590070112115, "DOCETAXEL": 1.432946360010918, "EBIXA": 1.0628740919527206, "EDOXABAN": 3.3669984472199115, "EMEND": 1.2152924669054894, "EMPAGLIFLOZIN": 2.71841044955868, "ENTRESTO": 3.797685865757976, "EPOETIN": 1.279986687181043, "ERLEADA": 2.464220997558076, "ESOMEPRAZOLE": 1.4781939286068435, "EUCREAS": 2.233242635202733, "EVISTA": 2.173123166553942, "EXFORGE": 11.27238366564034, "EXJADE": 1.524376821575517, "EXVIERA": 3.715158297096089, "FAMPYRA": 1.2419625280328308, "FEBUXOSTAT": 2.0153264957652595, "FORSTEO": 1.491193284392216, "GALAFOLD": 1.7574001665218597, "GALVUS": 2.801378047410939, "GENVOYA": 1.1177370980059964, "GLIBENCLAMIDE": 2.566651853169521, "GLIVEC": 3.602497233283783, "HARVONI": 1.3522356567332805, "HERCEPTIN": 1.1661291653381176, "HYDROCHLOROTHIAZIDE": 2.47609353786058, "ICLUSIG": 1.018249807039655, "IMATINIB": 1.310893245805396, "IMBRUVICA": 2.888846967565688, "INCIVO": 2.2919966713737905, "INSULIN": 1.5281622038599787, "IRBESARTAN": 2.9372207252676663, "IRON": 1.338160035104242, "IVABRADINE": 18.086521302271574, "JAKAVI": 1.8641854604916184, "JANUMET": 1.0402798405601934, "JANUVIA": 1.6520612959130594, "KETOCONAZOLE": 2.753608157937103, "KISQALI": 1.389736293729804, "LAMIVUDINE": 1.4038051626858568, "LENVIMA": 2.122636973033883, "LEVODOPA": 1.106974695436406, "LIXIANA": 1.8703343783908992, "LYRICA": 2.1250600396045454, "MACITENTAN": 3.568872015586262, "MEKINIST": 1.7046503767040744, "MELPHALAN": 1.125254172351677, "MENVEO": 1.2330575253930145, "MICARDIS": 2.1783737509121246, "MULTAQ": 4.365051480602233, "NEXAVAR": 1.4217936649894578, "NOT": 1.7894668826261022, "NOVONORM": 1.076446373727354, "NOXAFIL": 1.3346463999645914, "NPLATE": 2.073364648811989, "OCALIVA": 2.6813740826178183, "OLANZAPINE": 1.195810643205517, "OLYSIO": 1.395611591279919, "ONGLYZA": 1.220496718943471, "OPSUMIT": 5.1701702412845005, "OPTIMARK": 7.379097580892623, "PANTOPRAZOLE": 1.1551834975052604, "PAZOPANIB": 1.0787266215221565, "PEGINTERFERON": 1.0528684551194365, "PEMBROLIZUMAB": 1.0558803480264998, "PEMETREXED": 2.0148124283467843, "PIOGLITAZONE": 1.771022624974748, "PRADAXA": 1.2045622847360102, "PRAMIPEXOLE": 11.577403354098026, "PROPRANOLOL": 1.2170709568552556, "PROTELOS": 3.442064461322108, "RANEXA": 1.689271156137033, "RAPAMUNE": 2.28412758020039, "RASILEZ": 4.973542272350369, "REBETOL": 1.372612292157195, "REGORAFENIB": 2.3460148261258373, "REVATIO": 2.096600197750676, "REVLIMID": 1.5094914558567143, "RIVAROXABAN": 4.082292613670128, "ROACTEMRA": 1.962663742094036, "SAMSCA": 3.254683779829601, "SIFROL": 5.378747567457739, "SILDENAFIL": 2.135272736936991, "SOLIRIS": 1.2912928015293157, "SOVALDI": 2.315672842128636, "SPIRONOLACTONE": 3.818025650372767, "SPRYCEL": 1.9581530189719811, "STIVARGA": 1.6680573318194702, "SUBOXONE": 1.319153512356013, "SUTENT": 1.3755186587432466, "TASIGNA": 1.6618444043785172, "TAXOTERE": 1.0818690175900076, "TELMISARTAN": 3.0004241882566376, "THALIDOMIDE": 3.145178411541293, "TOCILIZUMAB": 1.25048693831945, "TORISEL": 2.14909283068786, "TOUJEO": 1.2770040771408788, "TOVIAZ": 1.3563764116004726, "TRACLEER": 4.762629962140861, "TRESIBA": 1.293511520845379, "TWYNSTA": 12.1722214162604, "VALSARTAN": 3.695945447149588, "VELCADE": 2.60668859245986, "VFEND": 1.0078376127875637, "XALKORI": 7.280379713610663, "XARELTO": 1.0934781783461085, "XOFIGO": 1.2391941465446608, "XOLAIR": 1.3730854628335945, "XTANDI": 1.831730069196355, "ZEPATIER": 1.2250515989228536, "ZOSTAVAX": 1.0226200651080597, "ZYPREXA": 2.180975493732439, "null": 1.3426031058703074}
\ No newline at end of file
+{"null": 0.70754727037457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5808.json
index 47ebc4356a6..9c21761c4fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5808.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5808.json
@@ -1 +1 @@
-{"BUSULFAN": 24.938014720560727, "BYETTA": 11.54977510854166, "JANUVIA": 15.763101205581638, "NOXAFIL": 80.13697504153676, "SAXENDA": 15.68004635983038, "VICTOZA": 28.364171785632944}
\ No newline at end of file
+{"null": 0.5610331033905649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5809.json
index 82b15eb808f..44f3060d2d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5809.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5809.json
@@ -1 +1 @@
-{"null": 1.033298285924836}
\ No newline at end of file
+{"null": 1.172156450325345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/581.json
index 0ffd3a5014e..f4aeb655ea8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/581.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/581.json
@@ -1 +1 @@
-{"BYETTA": 15.156697003631898, "COMBIVIR": 44.60740897940171, "GARDASIL": 6.2699308076641325, "JANUMET": 19.56527879529214, "JANUVIA": 22.048758276953723, "LANTUS": 1.2242127717534992, "OPSUMIT": 3.6138740843140384, "PEGASYS": 2.226816329081166, "ROTATEQ": 42.45810536472584, "STELARA": 3.8059938970856826, "ZOSTAVAX": 6.517461369328814}
\ No newline at end of file
+{"ENTYVIO": 22.92506793389697, "PEGASYS": 4.660851110761988, "SUTENT": 10.162914772680605, "null": 0.9697234911887308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5810.json
index dbe129b2296..83c2bfa11cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5810.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5810.json
@@ -1 +1 @@
-{"KALETRA": 33.00140241118983, "null": 1.9665602545876208}
\ No newline at end of file
+{"null": 0.7452144221444468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5811.json
index dfd9bb6ce47..72176dac51f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5811.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5811.json
@@ -1 +1 @@
-{"ABACAVIR": 9.745763986665612, "ALIMTA": 4.050268647332098, "AMINOSALICYLIC": 3.2860666445853672, "ASPARAGINASE": 31.79229053316334, "ATAZANAVIR": 10.04628461425767, "CELLCEPT": 2.2737530876965963, "CICLOSPORIN": 3.2040538992900043, "CIMZIA": 1.0302415523777553, "CLOPIDOGREL": 1.2344908458025368, "COSENTYX": 20.51816627698332, "DARUNAVIR": 19.67147825298624, "DELAMANID": 24.628368010155995, "JORVEZA": 321.3204320895036, "KALETRA": 12.206937488055887, "PEGINTERFERON": 3.590199469276407, "RELVAR": 66.59835607258583, "RITUXIMAB": 4.129937549063519, "STELARA": 1.376131753914001, "TACROLIMUS": 15.158382280624116, "TRELEGY": 7.981816764431218, "XALKORI": 6.359841939999329, "null": 1.2220383513999766}
\ No newline at end of file
+{"null": 6.297837356598585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5812.json
index 00cd24244a4..9b814ecfc87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5812.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5812.json
@@ -1 +1 @@
-{"CYTARABINE": 1.7947375368328766, "ENVARSUS": 73.47984765264044, "GREPID": 63.390300370528976, "TRELEGY": 1.4273883025543674, "null": 15.796353934681983}
\ No newline at end of file
+{"ABASAGLAR": 16.96847515543729, "ABILIFY": 0.6041747865548138, "ACTOS": 2.503170381466811, "ACTRAPID": 21.794126062401197, "AFINITOR": 5.647919568059884, "ALIMTA": 0.1979896212279088, "ALL": 2.932935963249306, "ALPELISIB": 66.83909950677229, "AMIKACIN": 0.4615941514502513, "AMINOSALICYLIC": 0.2772665906502141, "APIDRA": 46.02668627317476, "APREMILAST": 0.9050759099503362, "APROVEL": 2.458200316237769, "ARAVA": 0.0405093315998448, "ASPARAGINASE": 3.2303632958598945, "ATAZANAVIR": 0.3007629899595613, "AVAMYS": 0.3076654515666259, "AVANDIA": 0.5966514900487746, "AVASTIN": 0.2012511031973392, "AZATHIOPRINE": 0.1953401337053081, "BEVACIZUMAB": 0.2436378519325171, "BIKTARVY": 0.6144671286034751, "BLINATUMOMAB": 8.179014744524643, "BORTEZOMIB": 0.6173478250207582, "BRAFTOVI": 0.4900182536142113, "BRINTELLIX": 0.1771435589910149, "BUDESONIDE": 3.63763943376614, "BYDUREON": 0.8886445776371861, "BYETTA": 2.918997002838631, "CANAGLIFLOZIN": 25.818614097497424, "CAPECITABINE": 0.2980265096427827, "CELLCEPT": 0.5039122428214637, "CHAMPIX": 0.6101064776904115, "CICLOSPORIN": 0.2909542363192954, "CIMZIA": 0.0904147032688377, "CLOPIDOGREL": 0.257204554487443, "COAPROVEL": 2.197635865221809, "COMBIVIR": 0.8155042021132066, "COMIRNATY": 0.0754166613440102, "CORTICOSTEROID": 5.6333498978372845, "CORTICOSTEROIDS": 5.122187241592768, "CRIXIVAN": 4.466980246257307, "CYMBALTA": 0.1402537966008794, "CYTARABINE": 1.3953438927045263, "DAPAGLIFLOZIN": 5.839174150484727, "DENOSUMAB": 1.5171072249204305, "DEVICE": 59.36372930017131, "DEXAMETHASONE": 1.550711603132395, "DOCETAXEL": 0.2968988446726678, "DOXORUBICIN": 0.4033350779852742, "ELIQUIS": 0.1045289857069199, "EMPAGLIFLOZIN": 2.95399909357365, "ENTRESTO": 0.2478758763927321, "EPIVIR": 1.5243187942068923, "ERLEADA": 0.7658605612462396, "EUCREAS": 3.517447406920152, "EVISTA": 0.5317146103204615, "EXFORGE": 0.5732683443954081, "EXJADE": 0.1621472276735497, "EXUBERA": 12.53631536929412, "FASLODEX": 0.4373097792661365, 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"TIVICAY": 1.4203486918631285, "TORISEL": 3.779807369931933, "TOUJEO": 25.28186019143705, "TOVIAZ": 0.2677675248918073, "TOZINAMERAN": 0.1035565196215523, "TRESIBA": 23.6681744650378, "TRULICITY": 1.575333486536053, "VAXZEVRIA": 0.091680696230277, "VFEND": 0.2635108389291478, "VIAGRA": 0.2044504024460242, "VICTOZA": 1.900029803988537, "VILDAGLIPTIN": 3.876675118939951, "VIMPAT": 0.3214510083669373, "VOTRIENT": 0.1203283429910332, "XOLAIR": 0.1171431540779314, "XTANDI": 0.1250496974643772, "YERVOY": 0.6262015947111637, "ZOSTAVAX": 0.48038971229918, "ZYPREXA": 8.739558623725001, "null": 0.5326573438753003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5813.json
index 8be526363ce..34697948641 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5813.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5813.json
@@ -1 +1 @@
-{"LANTUS": 90.24235533198424}
\ No newline at end of file
+{"FORXIGA": 34.88895970917199, "ICOSAPENT": 2439.3512547825017, "JARDIANCE": 27.514479810608723, "OLANZAPINE": 12.929237270526803, "PIQRAY": 217.3686244158599, "ZYPREXA": 17.029439724273008, "null": 0.6681276006259282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5814.json
index 9e26ce3a150..d8ff5fb4e76 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5814.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5814.json
@@ -1 +1 @@
-{"null": 1.1186285327950696}
\ No newline at end of file
+{"null": 0.607446179040787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5815.json
index edf8e52fa2f..2d00c35c7d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5815.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5815.json
@@ -1 +1 @@
-{"null": 2.838728414981406}
\ No newline at end of file
+{"HUMALOG": 39.03968496107499, "LANTUS": 33.81493925125257, "LEVEMIR": 88.42910247616035, "NOVORAPID": 34.30007688463178, "null": 0.5052144834708597}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5816.json
index 76f5d1a4f3b..1c93d877847 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5816.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5816.json
@@ -1 +1 @@
-{"BUDESONIDE": 2.9723899984242563, "CYMBALTA": 2.346630337097233, "ELIQUIS": 2.9281528325634967, "IBRANCE": 1.9441335104033968, "KEYTRUDA": 1.6866339350912465, "NUCALA": 8.343097745566656, "PEGASYS": 1.616117987192392, "PLAVIX": 2.7366045691650527, "SOMATROPIN": 49.96482074252936, "SUTENT": 1.1535350615363504, "VIAGRA": 7.571547072739969, "null": 1.9143563798053385}
\ No newline at end of file
+{"null": 1.174616373878293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5817.json
index 58e14398f19..541cdeedeed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5817.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5817.json
@@ -1 +1 @@
-{"null": 1.4277695316070118}
\ No newline at end of file
+{"ABACAVIR": 6.291607386652432, "ABASAGLAR": 0.749368107153537, "ABILIFY": 0.5000338404313925, "ACLIDINIUM": 1.180085048508101, "ACTOS": 1.0278008619182688, "ACTRAPHANE": 3.458195749106008, "ACTRAPID": 1.5173443757157183, "ADCIRCA": 0.3253014922274709, "ADENURIC": 0.6274794999919907, "AERIUS": 0.6708059852017701, "AFINITOR": 0.1749143957918065, "AGOMELATINE": 3.735703102688356, "AIMOVIG": 0.9231028169146546, "ALEMTUZUMAB": 0.415273954598734, "ALIMTA": 0.1642498699481916, "ALL": 0.6355536797669636, "APIDRA": 2.608895210305412, "APIXABAN": 1.5147397317678288, "APROVEL": 0.6804625826761614, "ARANESP": 0.0826170025796168, "ARAVA": 0.0682945953672628, "ARIPIPRAZOLE": 0.6034975464143941, "ARSENIC": 3.787697675690107, "ASPARAGINASE": 0.0973988053017212, "ATAZANAVIR": 0.377080992498092, "AUBAGIO": 0.3664854854228515, "AVAMYS": 0.2935641278265337, "AVANDIA": 0.2535701367777653, "AVASTIN": 0.1740369992905982, "AZACITIDINE": 0.3116741783684129, "AZILECT": 1.48797873277654, "BAVENCIO": 0.5729831576566825, "BENLYSTA": 0.4378753180370192, "BETAFERON": 0.4823932136780796, "BETMIGA": 0.6630080579758345, "BEVACIZUMAB": 0.2106941831464607, "BEXSERO": 0.568578620027108, "BIKTARVY": 0.1774784651616536, "BOCEPREVIR": 0.5766566842865429, "BONVIVA": 0.5031699630661993, "BOTULINUM": 7.279417403782223, "BRAFTOVI": 0.1426588444040278, "BRILIQUE": 0.3784722484236986, "BRINTELLIX": 2.0147352164818577, "BRIVIACT": 0.2514698404629319, "BUDESONIDE": 0.2500130411955798, "BUPIVACAINE": 1.1401747241754234, "BUPRENORPHINE": 1.3265609538152827, "BUVIDAL": 2.217549279028442, "BYDUREON": 1.4668961059027288, "BYETTA": 0.5666196609465485, "CABAZITAXEL": 0.5829512984569466, "CABOMETYX": 0.1417942007029903, "CAELYX": 0.6981370444742406, "CANNABIDIOL": 0.4677781548892291, "CAPECITABINE": 0.1264804879755574, "CARBIDOPA": 0.8761325236529607, "CELECOXIB": 0.7813058538818015, "CELLCEPT": 0.1280199152541086, "CHAMPIX": 1.2010966797138944, "CICLOSPORIN": 0.140844326467429, "CIMZIA": 0.1580373312033001, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5818.json
index b529055ebd5..ed77e18cc8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5818.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5818.json
@@ -1 +1 @@
-{"APREPITANT": 221.55515272500247, "CLOPIDOGREL": 7.986215871109961, "ELIQUIS": 7.472711899787304, "NEXAVAR": 5.47133373356446, "PLAVIX": 19.13280329807113, "SUTENT": 3.692904151301261}
\ No newline at end of file
+{"null": 0.7046368370854855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5819.json
index e65103a936e..6d057f8c063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5819.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5819.json
@@ -1 +1 @@
-{"null": 1.1425222380734628}
\ No newline at end of file
+{"INSULIN": 27.4826214419794, "LANTUS": 5.084400336758828, "null": 1.4971757148412033}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/582.json
index e942ba87ffd..5893a8b8be0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/582.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/582.json
@@ -1 +1 @@
-{"ACLIDINIUM": 5.725439129869816, "ARANESP": 170.42240186197307, "BENLYSTA": 1.396915284244856, "BYDUREON": 1.5729628259199944, "CYTARABINE": 3.660852485868422, "DARBEPOETIN": 141.54596667567208, "ENTYVIO": 4.494765027478689, "FLUTICASONE": 33.41754705093679, "GARDASIL": 1.695109486699092, "IBRANCE": 1.0064512623896973, "INSULIN": 2.853004676275869, "JARDIANCE": 1.1376796262223536, "MELATONIN": 7.715629821638753, "PEGASYS": 1.477737002956917, "PEGINTERFERON": 1.509967931840989, "PEGINTRON": 5.360149010088953, "RINVOQ": 1.8978098416618727, "ROACTEMRA": 3.035884836961405, "SAXENDA": 3.4932959877051197, "SIMPONI": 1.057812181714984, "SPINRAZA": 2.5298747996263806, "STELARA": 1.577753695237463, "SUBOXONE": 1.122423328933079, "TOZINAMERAN": 1.8666345381317928, "TRULICITY": 1.0163986045047744, "VICTOZA": 2.31312756745515, "XELJANZ": 1.393795671786048}
\ No newline at end of file
+{"SUTENT": 36.236474889033325, "null": 0.9136107010113488}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5820.json
index a350d2dbb15..d2c3a319f64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5820.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5820.json
@@ -1 +1 @@
-{"null": 1.0452345623587092}
\ No newline at end of file
+{"ABASAGLAR": 65.58767067997874, "ACTRAPID": 48.3005349599956, "APIDRA": 69.58660120169772, "HUMALOG": 60.11148396594709, "INSULIN": 26.21869653362764, "LANTUS": 35.517962690977825, "LEVEMIR": 13.555503751415571, "NOVORAPID": 23.772787140978377, "null": 0.3369912271189988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5821.json
index 8d5712b19ea..daf7975d7ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5821.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5821.json
@@ -1 +1 @@
-{"null": 2.83139323334466}
\ No newline at end of file
+{"null": 1.6210800635805371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5822.json
index 0b40ebcc740..8bf4b254a89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5822.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5822.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 64.70018974451897, "null": 1.569900760278023}
\ No newline at end of file
+{"null": 3.932805869084876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5823.json
index fc45b024ca2..66956bacc25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5823.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5823.json
@@ -1 +1 @@
-{"null": 3.995992352689222}
\ No newline at end of file
+{"ABILIFY": 0.160476915094438, "ACE": 7.973155901355311, "ACTOS": 1.8245380407468896, "ACTRAPID": 1.0330908212792334, "ADENURIC": 9.77624542560364, "ADVAGRAF": 2.9614691106978674, "AERIUS": 1.3826005253778633, "AFINITOR": 0.2693581579948746, "ALEMTUZUMAB": 0.3150155658480618, "ALIMTA": 0.7355718564358256, "ALISKIREN": 3.846664079087128, "AMIKACIN": 0.9914105946456728, "AMINOSALICYLIC": 0.3863683553204355, "APIDRA": 0.5627505815178019, "APIXABAN": 0.1243718225071234, "APREMILAST": 1.156450028418593, "APROVEL": 30.76454710029234, "ARANESP": 0.4018460665010037, "ARIPIPRAZOLE": 1.8571851814379932, "ASPARAGINASE": 0.2816438346596109, "ATAZANAVIR": 0.9783465641774592, "ATRIPLA": 0.2683932433257751, "AVANDIA": 0.3491163979468956, "AVASTIN": 0.2571213163875751, "AXITINIB": 1.98921844730731, "BEDAQUILINE": 0.4670711821115649, "BENZODIAZEPINE": 2.922686086115226, "BEXTRA": 3.5592348383079604, "BIKTARVY": 0.3491434531341289, "BINOCRIT": 4.184913791176711, "BORTEZOMIB": 0.8664199793802754, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5824.json
index bb0f10b430d..cd6a488d6b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5824.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5824.json
@@ -1 +1 @@
-{"null": 1.7106632264816388}
\ No newline at end of file
+{"null": 1.0160645214141928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5825.json
index 36fc81b0461..37d0b39cfdb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5825.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5825.json
@@ -1 +1 @@
-{"APREPITANT": 3985.207007354716}
\ No newline at end of file
+{"AFINITOR": 1.2323768636173538, "CABOMETYX": 13.130182007419895, "CICLOSPORIN": 3.757988066758605, "COBIMETINIB": 35.02899556986354, "COMIRNATY": 0.078741882331006, "CONTRAST": 29.147141242189623, "COSENTYX": 1.4251087622488252, "CYMBALTA": 1.4121223617995196, "HUMALOG": 2.3333756488442043, "IMATINIB": 16.484816635549095, "INLYTA": 15.080731101288189, "JAKAVI": 2.053906392331211, "LANTUS": 1.108763156495154, "MEKINIST": 5.89885166852538, "NEXAVAR": 23.754024647137253, "OPTIMARK": 16.368438239246608, "SIMPONI": 0.9478246980941534, "SORAFENIB": 18.3733643542266, "SPIKEVAX": 0.0633984862254086, "STELARA": 0.7544990975324177, "STIVARGA": 21.792225227511054, "SUTENT": 19.39457401821049, "TAFINLAR": 31.339646439611634, "TREMFYA": 4.680366122822149, "VEMURAFENIB": 100.8274759295399, "VOTRIENT": 4.669224456159599, "XELJANZ": 1.446595330345872, "ZELBORAF": 75.66767677058583, "ZOSTAVAX": 3.877681562998301, "ZYPREXA": 0.8082686040308604, "null": 0.5600599053454921}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5826.json
index 3093ce4fcc0..74fe7bfe544 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5826.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5826.json
@@ -1 +1 @@
-{"null": 2.045398491126318}
\ No newline at end of file
+{"ARIPIPRAZOLE": 5.9943203297496686, "SIFROL": 57.07474492455968, "STALEVO": 34.63431122896784, "VAXZEVRIA": 0.2232108711523765, "ZYPREXA": 4.515965338120743, "null": 3.468219231173703}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5827.json
index 4a72b2dab81..ccbe8310f34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5827.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5827.json
@@ -1 +1 @@
-{"null": 2.0976434733784406}
\ No newline at end of file
+{"null": 3.612151837161976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5828.json
index bb5bdf448bb..a6204aecf7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5828.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5828.json
@@ -1 +1 @@
-{"null": 1.0924667414613298}
\ No newline at end of file
+{"ABACAVIR": 6.503108083219105, "AMIKACIN": 15.303986672376556, "COAPROVEL": 18.739929330402667, "COMBIVIR": 10.32615128872965, "EFAVIRENZ": 40.39872257930428, "EPIVIR": 45.66328965745541, "IBUPROFEN": 24.455305479800668, "JANUMET": 4.912850535698259, "KALETRA": 18.5598132830562, "KEPPRA": 1.46609069107637, "LAMIVUDINE": 26.679554344313985, "PLAVIX": 1.9212176070221192, "null": 2.33811532507788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5829.json
index 8d914194058..08e095f4958 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5829.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5829.json
@@ -1 +1 @@
-{"CHAMPIX": 1.3793215020567944, "CLOPIDOGREL": 6.793475314256406, "IBRANCE": 2.1298317227998886, "INLYTA": 4.114298365017184, "PLAVIX": 1.0005788544444671, "XALKORI": 8.37860289029666, "XELJANZ": 1.0398009963151391, "XTANDI": 1.7442749134807491, "null": 3.5285841559870312}
\ No newline at end of file
+{"COMIRNATY": 0.2931163108311664, "null": 0.8935515100829805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/583.json
index 16128d662d9..1d2d368d556 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/583.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/583.json
@@ -1 +1 @@
-{"PEGASYS": 1.5136436427368665, "SUBOXONE": 4.789270370465714, "TOZINAMERAN": 1.31017908956661, "XELJANZ": 4.250554405590314, "null": 1.032116347392365}
\ No newline at end of file
+{"LYRICA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5830.json
index 5b95f8809a8..d2154e2d1b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5830.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5830.json
@@ -1 +1 @@
-{"DULOXETINE": 69.61531964138896, "ENVARSUS": 1472.667815408806, "KEYTRUDA": 6.376720843017223}
\ No newline at end of file
+{"COMIRNATY": 0.1149567720383105, "FORXIGA": 13.9117711774439, "JANUVIA": 16.563816658372744, "KALETRA": 15.7307463277005, "KEYTRUDA": 3.040108898540009, "OPDIVO": 10.321826929736323, "TRULICITY": 15.749250667716074, "VICTOZA": 30.111898522614144, "null": 0.8728584687409205}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5831.json
index 1a532b9306f..f1b64615d04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5831.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5831.json
@@ -1 +1 @@
-{"MEPOLIZUMAB": 131.71038952237984}
\ No newline at end of file
+{"ABACAVIR": 1.859515225496162, "ABILIFY": 1.1340977667660217, "ADCIRCA": 4.939578954714165, "AFINITOR": 4.739708554037388, "ANAKINRA": 2.067139968870847, "ARAVA": 0.1247740823018683, "ARIPIPRAZOLE": 0.8818026195566057, "ASPARAGINASE": 6.827131841990698, "ATAZANAVIR": 11.279086682793192, "ATRIPLA": 0.7990647973205487, "AVANDAMET": 15.304757636588963, "AVANDIA": 10.894237758081053, "AVONEX": 13.656772461726051, "BIKTARVY": 4.419280726988122, "BRILIQUE": 2.0033541418574217, "BUSULFAN": 2.851583293921191, "BYDUREON": 2.8183370965383414, "BYETTA": 13.93052111593498, "CELLCEPT": 1.7935700034760684, "CIALIS": 4.889486707741651, "CICLOSPORIN": 1.7945433772993356, "CLOPIDOGREL": 0.8816910163710777, "COMBIVIR": 4.525457452996397, "COMIRNATY": 0.0517727019709697, "COSENTYX": 0.6961106211915308, "CRIXIVAN": 13.585619849108884, "CYMBALTA": 0.877085283832532, "CYTARABINE": 2.0138679805726807, "DARUNAVIR": 17.034228607124298, "EDURANT": 29.80580741826289, "EFAVIRENZ": 12.836098631899391, "ELIQUIS": 0.9812669187853484, "EMPAGLIFLOZIN": 3.780612691865135, "ENBREL": 0.5691419454747467, "ENTRESTO": 1.144364157147408, "EPIVIR": 2.963032159665238, "EXFORGE": 2.433001099534673, "FASLODEX": 1.630640644378359, "GARDASIL": 0.2470190194504594, "HUMALOG": 1.1316398626193265, "IBRANCE": 0.3427228625399233, "ICLUSIG": 2.1600304147834417, "INDINAVIR": 33.96573037562357, "INSULIN": 1.4383955845767549, "ISENTRESS": 2.982879970423149, "JANUMET": 15.578169888155136, "JANUVIA": 11.766845045807733, "JARDIANCE": 0.3380820961157156, "KALETRA": 4.686529926649116, "KEYTRUDA": 0.2973621202511122, "LANTUS": 0.7535297831928756, "LYRICA": 2.662946656003094, "NOT": 3.158938388842871, "OLANZAPINE": 2.7456607852480346, "ONCASPAR": 7.555458285586069, "ONGLYZA": 5.668924786666238, "PEGASYS": 0.3002924690191598, "PEGINTRON": 0.4424992283874104, "PLAVIX": 1.39044553507149, "RAPAMUNE": 4.32226579628449, "RINVOQ": 1.563507325553516, "ROACTEMRA": 1.8088914754774883, "SHINGRIX": 0.7594215915485635, "SPIKEVAX": 0.0826774556524378, "STELARA": 0.4867501629953153, "SUTENT": 0.4080787564485423, "TASIGNA": 7.027847791522514, "TIVICAY": 6.78991836222758, "TORISEL": 4.02508443267051, "TOZINAMERAN": 0.0655631349150809, "TRUVADA": 0.4556913553725293, "VAXZEVRIA": 0.0130497490724355, "VIAGRA": 1.1896295972255255, "XELJANZ": 0.5303342748833765, "ZOSTAVAX": 29.05626724884087, "ZYPREXA": 16.807143223473794, "null": 0.8701979647756894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5832.json
index d8a52ff37e4..b2b4fa08cb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5832.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5832.json
@@ -1 +1 @@
-{"null": 1.7052383257484258}
\ No newline at end of file
+{"null": 6.182606950960828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5833.json
index 1468a2790d3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5833.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5833.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 20.317414140912863, "CYMBALTA": 2.8474691023159324, "XOLAIR": 5.055931464545518, "null": 1.9788445322269028}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5834.json
index 47bd0ea86b3..aa5ffbfb582 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5834.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5834.json
@@ -1 +1 @@
-{"COSENTYX": 3.171997578848048, "DEXAMETHASONE": 4.443102338622094, "IBRANCE": 2.4235391458587423, "KEYTRUDA": 3.139119323043714, "null": 1.753155099484737}
\ No newline at end of file
+{"COMIRNATY": 0.4286319856628351, "null": 0.6836701333954871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5835.json
index 98ed1b30bdf..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5835.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5835.json
@@ -1 +1 @@
-{"BONVIVA": 13.964751634701608, "CELLCEPT": 3.877766852691498, "CICLOSPORIN": 1.461144997691845, "CLOPIDOGREL": 4.118372943234711, "COMBIVIR": 6.6332895650558505, "COSENTYX": 2.40515574524744, "ENBREL": 2.264334979348395, "KEYTRUDA": 1.3082381112927024, "NEXAVAR": 3.5069615807318923, "PLAVIX": 7.309920750555538, "SUTENT": 4.2642676942846585, "XALKORI": 39.54303907059105, "null": 1.877144486042149}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5836.json
index 832fae36c45..b2de97fe930 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5836.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5836.json
@@ -1 +1 @@
-{"ELIQUIS": 5.317679950065124, "PLAVIX": 19.72427474693973, "null": 1.27692002496126}
\ No newline at end of file
+{"COMIRNATY": 0.2832997178202974, "GARDASIL": 3.968422311759035, "HUMALOG": 2.941053191848288, "OZEMPIC": 234.29481117765732, "ZOSTAVAX": 22.84014992171198, "null": 1.9983765410385872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5837.json
index 8aadab1fe2d..e0f0654b9da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5837.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5837.json
@@ -1 +1 @@
-{"ATAZANAVIR": 9.80135768428901, "AVASTIN": 7.760295211814483, "DAKLINZA": 31.465047549163856, "ELIQUIS": 1.411732053533892, "EPCLUSA": 32.49532311478416, "EXVIERA": 23.090356520143576, "HARVONI": 39.19669618351153, "JAKAVI": 14.852709006818234, "LENVIMA": 45.64002112013237, "NEXAVAR": 64.93929950231525, "OCALIVA": 39.952015691301774, "PEGASYS": 7.543699955078122, "PEGINTRON": 3.1623683826218723, "PLAVIX": 1.923316060242337, "REBETOL": 25.72096970609256, "RIBAVIRIN": 26.03871474924258, "SOVALDI": 38.12947358924573}
\ No newline at end of file
+{"ARAVA": 6.647507794131284, "COMIRNATY": 0.0891335956229255, "CYMBALTA": 4.413218134794631, "GARDASIL": 34.5737603775742, "null": 1.6488494339943656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5838.json
index 3aa64d54e9d..2195d0e7700 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5838.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5838.json
@@ -1 +1 @@
-{"ALIMTA": 4.193420773445412, "AVASTIN": 1.9928587084220604, "BEVACIZUMAB": 4.111529694515274, "BONVIVA": 20.14578747238701, "BRILIQUE": 1.8191521767922203, "BUPRENORPHINE": 3.557041080146793, "BUSULFAN": 1.934707875608048, "BYETTA": 1.3754602665129148, "CAPECITABINE": 2.9485847260199187, "CELLCEPT": 2.484503976516243, "CHAMPIX": 1.7594502747128529, "CLOPIDOGREL": 2.678482801731417, "COSENTYX": 1.2204856225054734, "CYTARABINE": 1.9700434954044832, "DABRAFENIB": 10.19261524565018, "DACLATASVIR": 14.351529796099808, "DOCETAXEL": 3.056369699064993, "ELIQUIS": 1.2964905478529238, "ESOMEPRAZOLE": 5.102870786981723, "EXJADE": 1.972832080760374, "FORSTEO": 1.0822446409939288, "IBRANCE": 1.3648658050255065, "IBUPROFEN": 2.7239424092858573, "JANUMET": 1.9892984747698532, "JANUVIA": 1.028970180324619, "KEYTRUDA": 1.742032997400133, "OPDIVO": 2.219618530629032, "PANTOPRAZOLE": 2.9722990858142424, "PEGASYS": 1.0245343178120454, "PLAVIX": 3.2582806962705613, "PRADAXA": 16.670901475394526, "SAXENDA": 1.6725401402673117, "SPRYCEL": 1.737068947219613, "SUTENT": 2.1064233860845234, "VOTRIENT": 1.1955430989400873, "XALKORI": 16.014376240973323, "null": 1.8061134066076543}
\ No newline at end of file
+{"TEMOZOLOMIDE": 3989.270212284088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5839.json
index 28b74956af2..a9de59b95bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5839.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5839.json
@@ -1 +1 @@
-{"null": 4.172004983808182}
\ No newline at end of file
+{"ARIPIPRAZOLE": 2.90471677272578, "BRINTELLIX": 1.7622343519534809, "BUMETANIDE": 19.02080233809311, "COMIRNATY": 0.0603843173132516, "CYMBALTA": 0.667000520514628, "CYTARABINE": 1.6975240476337696, "DEXAMETHASONE": 1.188686304059364, "ELIQUIS": 0.7575391638106291, "FENTANYL": 1.4542873739927478, "FORXIGA": 10.743340543396483, "JARDIANCE": 8.934460427879404, "KEPPRA": 1.5438152081781185, "LEVETIRACETAM": 3.493030303050896, "LEVOFLOXACIN": 1.6522268895953771, "OLANZAPINE": 6.285791413945478, "PANTOPRAZOLE": 6.210011231244325, "PRADAXA": 15.817071719979564, "SAMSCA": 314.1517471146926, "TOLVAPTAN": 175.80328272586783, "ZYPREXA": 3.954822764883928, "null": 2.8464951792009643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/584.json
index 4482360e89c..64dc0f28d65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/584.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/584.json
@@ -1 +1 @@
-{"ACLIDINIUM": 18.89066446471517, "ARANESP": 2225.6922003734244, "BUDESONIDE": 1.6289224494652492, "DARBEPOETIN": 482.6031003037765, "FLUTICASONE": 111.87200361338776, "INSULIN": 5.622198272191772, "MELATONIN": 23.776460596043343}
\ No newline at end of file
+{"CHAMPIX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5840.json
index a9981f35136..adcef590cc0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5840.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5840.json
@@ -1 +1 @@
-{"PLAVIX": 16.360918015580044, "SUTENT": 3.763293724415581, "null": 1.3569443769995166}
\ No newline at end of file
+{"GLIBENCLAMIDE": 292.1432991117906, "ZYPREXA": 25.421020597272967, "null": 1.402937741052847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5841.json
index 277fa284876..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5841.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5841.json
@@ -1 +1 @@
-{"DOXORUBICIN": 464.68485732743153, "null": 1.7058820093978926}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5842.json
index 1fe83577762..762b2252d72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5842.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5842.json
@@ -1 +1 @@
-{"FASLODEX": 47.44933469930247, "TESTOSTERONE": 182.0430068416356, "null": 4.375679922124095}
\ No newline at end of file
+{"null": 2.4396486689105443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5843.json
index 0a4230d8877..1e31bc5ec69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5843.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5843.json
@@ -1 +1 @@
-{"null": 2.748830212428649}
\ No newline at end of file
+{"ACALABRUTINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5844.json
index 8a94bcf4b4c..bf9bce8956f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5844.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5844.json
@@ -1 +1 @@
-{"IBRANCE": 13.605110566070923, "null": 4.831632651095809}
\ No newline at end of file
+{"ARANESP": 14.11107369596022, "ATRIPLA": 3.728871101262186, "CELLCEPT": 7.690236417208235, "FORSTEO": 5.065236133670494, "MIMPARA": 27.879968664447784, "PEGASYS": 6.265516394401678, "TRUVADA": 4.462040415720573, "ZOSTAVAX": 3.6295913312727777, "null": 1.8790647298783552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5845.json
index 352e14f72bc..edd85171f67 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5845.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5845.json
@@ -1 +1 @@
-{"ABACAVIR": 2.4683448679906657, "ABILIFY": 1.316990288806794, "ABIRATERONE": 1.1979462262958298, "ABRAXANE": 1.892877295551597, "ACALABRUTINIB": 6.148326864036193, "ACETYLSALICYLIC": 1.432782581757112, "ACLIDINIUM": 1.0095561911128523, "ADALIMUMAB": 1.9917778206136456, "ADCETRIS": 3.739881920948621, "AFLIBERCEPT": 2.457966878930715, "AGOMELATINE": 2.166901394186165, "AIMOVIG": 1.8395546112189776, "ALEMTUZUMAB": 4.53368741691868, "ALIGN": 3.880435553525409, "ALIMTA": 3.983355233904703, "AMELUZ": 10.961417770735672, "AMGEVITA": 1.0346355689144031, "AMIKACIN": 2.241205505901953, "AMINOSALICYLIC": 2.9539539445469054, "ANAGRELIDE": 1.773070843290049, "ANAKINRA": 3.588936772623088, "ANGIOX": 2.215416147262464, "APREMILAST": 1.762067563311652, "ARAVA": 1.6837411781589957, "ARIPIPRAZOLE": 1.5288377777499529, "ARIXTRA": 1.2419061356117884, "ATEZOLIZUMAB": 2.0011936171566296, "ATOSIBAN": 1.0021670551870676, "AVAMYS": 1.4771045067699415, "AVASTIN": 1.0371420934873423, "AVELUMAB": 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2.919365000850682, "XARELTO": 1.020863436194093, "XELJANZ": 1.970107311664388, "XEPLION": 1.2886366345363902, "YERVOY": 1.3393004262131962, "ZEJULA": 1.59248205465249, "ZELBORAF": 1.3933547021349106, "ZEVALIN": 2.2929224490737914, "ZYCLARA": 1.267410033598139, "ZYPREXA": 1.2215971227083804}
\ No newline at end of file
+{"null": 2.9533725008112346}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5846.json
index 9d39687dd80..2711c648127 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5846.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5846.json
@@ -1 +1 @@
-{"null": 5.87698667678919}
\ No newline at end of file
+{"ANAKINRA": 59.29359095841062, "ARANESP": 13.350582286330484, "ATRIPLA": 12.725928471375267, "TRUVADA": 12.64441609693646, "null": 0.6168336929657802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5847.json
index cda756fc5c4..c945a5faeaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5847.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5847.json
@@ -1 +1 @@
-{"null": 1.51951164243297}
\ No newline at end of file
+{"ABACAVIR": 3.801172835424252, "ABILIFY": 5.829038562087598, "APIDRA": 6.447837286969352, "ARIPIPRAZOLE": 8.614023614179391, "BIKTARVY": 9.106304444674963, "CHAMPIX": 3.619060167909501, "COMIRNATY": 0.0452470562964267, "CYMBALTA": 2.8953914979000244, "HUMIRA": 16.165179724047775, "OLANZAPINE": 7.080802825994087, "SIFROL": 20.000566725393885, "TOZINAMERAN": 0.2645706185770316, "VAXZEVRIA": 0.0846644784664606, "ZYPREXA": 23.176904236376306, "null": 1.3059007273941623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5848.json
index 0b76da26390..7235cffca44 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5848.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5848.json
@@ -1 +1 @@
-{"BUDESONIDE": 13.786102168972665, "COMIRNATY": 1.5131996464485529, "IBUPROFEN": 45.39573188822148}
\ No newline at end of file
+{"ZYPREXA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5849.json
index 2f50700620b..735edf66941 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5849.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5849.json
@@ -1 +1 @@
-{"MMRVAXPRO": 70.21447117876387, "null": 1.5373359914414144}
\ No newline at end of file
+{"ARANESP": 323.63854751957194, "ATRIPLA": 1.0090153930042247, "BLINATUMOMAB": 211.95152612027783, "FORXIGA": 4.523265307877876, "MELATONIN": 32.785868816720985, "MIMPARA": 21.13003939953836, "TRUVADA": 2.016318942228509, "null": 0.6132010751637905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/585.json
index a94bc1b078a..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/585.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/585.json
@@ -1 +1 @@
-{"null": 5.228685282958513}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5850.json
index 1b9f1604e0a..006beea82d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5850.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5850.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.3448712863638488, "CIMZIA": 1.458922193142835, "COMBIVIR": 10.299848992273906, "DEXAMETHASONE": 3.1002916826363176, "EXFORGE": 4.095754414978354, "FENTANYL": 3.814538290374758, "HERCEPTIN": 7.314465437185395, "SUBOXONE": 6.366391662804304, "TELMISARTAN": 27.02468754792876, "ZYPREXA": 1.3675836922519888, "null": 4.319353368958843}
\ No newline at end of file
+{"HEPSERA": 925.0294550685296, "null": 0.6236113365267257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5851.json
index aa34bbc9ee9..8baf3911bcb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5851.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5851.json
@@ -1 +1 @@
-{"COMIRNATY": 17.332305685473493, "SPIKEVAX": 2.5452551465113684}
\ No newline at end of file
+{"TRUVADA": 13.416712855848262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5852.json
index 685c0506a2b..128ac2a2a16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5852.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5852.json
@@ -1 +1 @@
-{"null": 6.421723954633703}
\ No newline at end of file
+{"ASPARAGINASE": 43.44421060422945, "COMIRNATY": 0.1357823316788055, "null": 1.584144891978018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5853.json
index 609551a3118..e56fdd3f680 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5853.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5853.json
@@ -1 +1 @@
-{"ADEMPAS": 6.724281081010858, "AMIKACIN": 4.12182206682986, "AZILECT": 13.40145811821922, "CELECOXIB": 3.5625772667323896, "CELLCEPT": 2.090245901097928, "CICLOSPORIN": 5.668743296635772, "CLOPIDOGREL": 1.072388331596034, "COAPROVEL": 4.8998604666256425, "DAPTOMYCIN": 16.858437902920198, "DEXAMETHASONE": 2.0176712126055905, "ENOXAPARIN": 4.93564172396745, "ENTRESTO": 2.3769549331181525, "EXJADE": 1.2796102200909087, "GANCICLOVIR": 6.232025790696159, "IBUPROFEN": 3.4213792468862194, "IRBESARTAN": 3.6716842470271143, "KALETRA": 4.35374220437765, "KYMRIAH": 4.218055009751324, "LEVETIRACETAM": 2.231500098946488, "LEVOFLOXACIN": 5.929156138332552, "LYRICA": 1.6837296856621748, "MIDAZOLAM": 3.1682871995420645, "OPSUMIT": 1.2407345865474155, "OVITRELLE": 30.542230143812077, "RASILEZ": 6.340160121615348, "SOLIRIS": 2.401780381679244, "SPIRONOLACTONE": 5.320506039465583, "TELMISARTAN": 5.370400027937494, "null": 3.030528413522446}
\ No newline at end of file
+{"null": 0.6718273461206041}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5854.json
index 6a7155cd2be..dcfc16596bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5854.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5854.json
@@ -1 +1 @@
-{"COMIRNATY": 2.146884941059276}
\ No newline at end of file
+{"ADCIRCA": 3312.9141942980823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5855.json
index f89c06886ab..71d838899e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5855.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5855.json
@@ -1 +1 @@
-{"REMICADE": 251.48931049945924}
\ No newline at end of file
+{"ABILIFY": 10.573632723244025, "ARIPIPRAZOLE": 31.13105569708262, "BRINTELLIX": 7.251190203791279, "COMIRNATY": 0.0306940553161097, "CYMBALTA": 1.2491951320460064, "INVEGA": 132.46205883078724, "LATUDA": 51.74356191240668, "LURASIDONE": 169.6362941259309, "OLANZAPINE": 39.33898268311663, "RISPERIDONE": 25.00432169848642, "ZYPREXA": 14.304159997413674, "null": 2.6464934438712207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5856.json
index 893ff665e7b..89eb5406534 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5856.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5856.json
@@ -1 +1 @@
-{"AZILECT": 344.7596214391791, "CARBIDOPA": 533.3204676001469, "COMTAN": 114.64384055491416, "ENTACAPONE": 624.7224564583022, "LEVODOPA": 850.806344389586, "SIFROL": 71.00047408638419, "STALEVO": 227.7982496854132}
\ No newline at end of file
+{"null": 0.6391236183990162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5857.json
index a2867a9a9ec..12a1571d349 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5857.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5857.json
@@ -1 +1 @@
-{"AFINITOR": 21.26754160233977, "TASIGNA": 42.08369048026828, "XTANDI": 17.07118321948716}
\ No newline at end of file
+{"AFINITOR": 0.2785436226191713, "ALEMTUZUMAB": 0.6926675975529242, "ALIMTA": 0.6223095286210317, "BEXSERO": 6.033188628178409, "BRINTELLIX": 0.546758076225431, "CLOPIDOGREL": 0.1495809918312125, "COMIRNATY": 1.14649812527001, "DABRAFENIB": 4.713689506436015, "DARZALEX": 3.3493200589099232, "DEXAMETHASONE": 0.3357265768187068, "EXJADE": 0.3744025417335064, "FASENRA": 0.7517983668976782, "FLEBOGAMMA": 1.8408949016088103, "GANCICLOVIR": 2.218929768062478, "GARDASIL": 1.254999182559976, "HALAVEN": 2.8565623223516066, "HERCEPTIN": 1.4690023273015889, "HEXYON": 169.63819112844877, "IBRANCE": 0.147955015725666, "INCIVO": 0.6187866973393861, "INFANRIX": 76.74711253996689, "KEYTRUDA": 0.3055643005069453, "LEVOFLOXACIN": 1.012119369706245, "MABTHERA": 2.147906795748211, "MEKINIST": 4.2672086464234935, "MENVEO": 9.755469328811758, "MMRVAXPRO": 61.9294216501321, "NEXAVAR": 0.4898647591376771, "NIMENRIX": 11.590817879324767, "OLANZAPINE": 0.572590453639119, "PEGASYS": 0.1563300415630385, "PEGINTRON": 0.2836745738770619, "PERJETA": 6.544825074071549, "PLEGRIDY": 1.0369110796931431, "PREVENAR": 9.040335632377165, "PRIVIGEN": 2.027474039395833, "PROQUAD": 29.4796726585562, "ROTATEQ": 1.6661972508207474, "SHINGRIX": 0.9868536991101402, "SPIKEVAX": 1.601415231276092, "STIVARGA": 0.5834872975301861, "SUTENT": 0.2072466882894142, "TAFINLAR": 16.748828454881412, "TOZINAMERAN": 0.1646167041458705, "VAXZEVRIA": 2.0110977485623733, "YERVOY": 1.7593311277757944, "ZYPREXA": 0.36821224490898, "null": 0.918567096366834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5858.json
index 0e1fd07e5de..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5858.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5858.json
@@ -1 +1 @@
-{"SUTENT": 5.006097738890476}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5859.json
index 5dd2afb04d5..d2a6beef167 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5859.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5859.json
@@ -1 +1 @@
-{"AFINITOR": 6.931663734707629, "AIMOVIG": 2.475155971563972, "APIXABAN": 2.508279712699573, "AUBAGIO": 6.33619214659702, "CICLOSPORIN": 1.2264183542408578, "DAPAGLIFLOZIN": 97.83932439009328, "ENBREL": 3.1066982828464145, "FASLODEX": 10.256181100661582, "FORSTEO": 2.9684354636912853, "HERCEPTIN": 9.586571978680464, "IBRANCE": 15.583683980199767, "IMBRUVICA": 46.11474460969721, "INSULIN": 3.878152757668662, "IRESSA": 7.312797983547702, "LONSURF": 13.521904378026498, "PEGASYS": 1.8697185730054016, "SUTENT": 2.2768250086522146, "TAGRISSO": 37.42974064973691, "XELJANZ": 1.3319750029225836}
\ No newline at end of file
+{"ARIPIPRAZOLE": 5.256023264049235, "CICLOSPORIN": 1.2385877376924428, "COMIRNATY": 0.1344670298285679, "COMTAN": 12.61071844826304, "CYMBALTA": 2.518630076073634, "DULOXETINE": 17.42922420826344, "EPIVIR": 12.526994702101018, "FENTANYL": 4.391217687215838, "GARDASIL": 1.9599453491006589, "IBUPROFEN": 6.066033988604476, "KEPPRA": 1.0049690946457286, "LEVETIRACETAM": 3.1893209471104256, "MIDAZOLAM": 3.801107260634944, "NAGLAZYME": 9.1409000221061, "OLANZAPINE": 8.815026618036176, "RISPERIDONE": 22.62011857434509, "SPIKEVAX": 0.0798155752049123, "TOZINAMERAN": 0.1824328924449367, "VAXZEVRIA": 0.1085566125470469, "ZYPREXA": 1.4294281946415583, "null": 3.886470971757684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/586.json
index f8f1ea29fbd..a00c5ce4e60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/586.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/586.json
@@ -1 +1 @@
-{"ELIQUIS": 3.290783196566647, "ENBREL": 8.868550832362711, "JANUVIA": 20.47425259671117, "ROTATEQ": 24.6155580379301, "SUBOXONE": 15.236042885069162}
\ No newline at end of file
+{"null": 1.3080303508864288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5860.json
index 702b96a99c5..fd9717f3f9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5860.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5860.json
@@ -1 +1 @@
-{"ARAVA": 3.859474178586268, "COSENTYX": 14.648129714292685, "DOCETAXEL": 18.73956889653857, "EVOLOCUMAB": 1639.7553507646785, "FASLODEX": 13.875084389138015, "SUTENT": 2.3182319402534266}
\ No newline at end of file
+{"COMIRNATY": 5.068857063625577, "null": 0.5143145869086995}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5861.json
index 769dc4fbc0a..e7de75ffed5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5861.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5861.json
@@ -1 +1 @@
-{"ABATACEPT": 29.414550483968867, "ADALIMUMAB": 35.376428467098215, "ARAVA": 1.0240287470433798, "AUBAGIO": 4.585422856277496, "CIMZIA": 7.63890452214577, "IBRANCE": 1.707813068534617, "KEYTRUDA": 1.0535336776738289, "OPTIMARK": 3.5367906725961964}
\ No newline at end of file
+{"ABACAVIR": 6.378976133651239, "ABASAGLAR": 0.9157336312767812, "ABATACEPT": 3.3405351907153142, "ABILIFY": 0.305250306125256, "ABLAVAR": 70.04082379006084, "ACETAMINOPHEN": 5.834682110638103, "ACLASTA": 2.3373591013416632, "ACLIDINIUM": 0.6861626409199633, "ACTOS": 0.4979266131559767, "ACTRAPID": 1.3985254291491829, "ADALIMUMAB": 2.73481565836246, "ADCIRCA": 0.4448729903612257, "ADEMPAS": 0.234680980832212, "ADENURIC": 0.9551040603766646, "ADVATE": 1.4748189220767445, "AERIUS": 1.8149726464048628, "AFINITOR": 0.1879661274294939, "AIMOVIG": 0.8888126771343735, "ALDARA": 0.3981480441503406, "ALEMTUZUMAB": 0.1206403159507732, "ALIMTA": 0.6986900922016706, "ALL": 2.4495782522228144, "ALLERGY": 11.663667858783253, "ALOXI": 2.270165281457616, "AMIKACIN": 0.2480870738280016, "AMINOSALICYLIC": 0.178246635743725, "ANAKINRA": 0.4957010190327384, "ANGIOX": 1.4334861664404237, "ANORO": 0.3453746905229195, "ANTIBIOTICS": 1.2841837805174416, "APIDRA": 0.9048927549116624, "APIXABAN": 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"XELODA": 0.4824222003419821, "XIAPEX": 3.46007082119764, "XOLAIR": 3.334261641298798, "XTANDI": 0.3382201546184383, "XYREM": 1.0620352280212535, "YERVOY": 0.2183682743793516, "ZARZIO": 1.3553008187822584, "ZELBORAF": 0.5357419138979862, "ZIAGEN": 11.9867810876284, "ZONEGRAN": 2.2341482219216244, "ZOSTAVAX": 1.1707104159038215, "ZYPREXA": 0.188910350142832, "null": 1.6693890889275769}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5862.json
index 4ccd7d3e6cf..dd1a761d5de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5862.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5862.json
@@ -1 +1 @@
-{"ADALIMUMAB": 32.21783678183156, "ARAVA": 1.948858634561311, "CIMZIA": 12.499882906579542, "CLOPIDOGREL": 1.9808518487111415, "COSENTYX": 2.2629235716491465, "RITUXIMAB": 4.016773770975223, "XELJANZ": 2.090557649308347, "ZOSTAVAX": 6.148349457915384, "ZYPREXA": 3.487010150680951}
\ No newline at end of file
+{"FONDAPARINUX": 5041.417620442084, "LEVOFLOXACIN": 16.741257951133942, "MILRINONE": 56617.2757639899, "SPIKEVAX": 0.4799372313960189, "null": 2.0667127171670003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5863.json
index 68ff5596382..f0117289657 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5863.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5863.json
@@ -1 +1 @@
-{"null": 2.999112472942262}
\ No newline at end of file
+{"COMIRNATY": 0.1853063937756783, "CUBICIN": 35.72259692881654, "KEYTRUDA": 1.769018306029921, "METHOTREXATE": 5.644980839759978, "NUCALA": 5.43856593908761, "PACLITAXEL": 18.198247742025284, "PEGASYS": 1.5133026955010862, "PEGINTRON": 2.632444135533732, "SPIKEVAX": 0.1270768272381368, "VAXZEVRIA": 0.3214635794905098, "null": 1.6028717237648495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5864.json
index 6124476d223..5d02c063c3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5864.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5864.json
@@ -1 +1 @@
-{"IBRANCE": 16.828134281834593, "null": 1.107714857676006}
\ No newline at end of file
+{"ARAVA": 0.641354006113743, "COMIRNATY": 0.3361358319938163, "ENBREL": 13.919752633654966, "FEBUXOSTAT": 37.9628319273163, "LEVOFLOXACIN": 3.4942947892279084, "SIMPONI": 2.639959384828207, "SPIKEVAX": 0.1595957932046716, "VAXZEVRIA": 0.1721114904716685, "null": 2.50106088982145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5865.json
index d7d20063b9d..c03bf52e0d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5865.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5865.json
@@ -1 +1 @@
-{"CYMBALTA": 4.378974673829317, "ZOSTAVAX": 18.17196269105628, "null": 1.979267116322484}
\ No newline at end of file
+{"ARIPIPRAZOLE": 17.83515750649777, "AZILECT": 213.63336841416935, "CANNABIDIOL": 88.82331307979784, "CARBIDOPA": 95.18692555569451, "ENTACAPONE": 165.4767100254095, "LEVETIRACETAM": 5.959144632861045, "LEVODOPA": 259.0407640781477, "SIFROL": 348.30223798376875, "STALEVO": 88.54307920972444, "null": 1.753035790574984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5866.json
index 25bcff04d30..0d78d780ba1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5866.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5866.json
@@ -1 +1 @@
-{"null": 1.1733358945517447}
\ No newline at end of file
+{"ABILIFY": 2.048806572874485, "AFINITOR": 0.5734164035466904, "AIMOVIG": 0.8349101597290997, "ARIPIPRAZOLE": 1.623911043753217, "ATRIPLA": 0.1113528332514268, "AUBAGIO": 1.6114098829512915, "AVAMYS": 0.6639439753854101, "BELIMUMAB": 26.559866388981927, "BENLYSTA": 1.2819438106908263, "BIKTARVY": 2.0124037593218724, "BRINTELLIX": 1.91677357321202, "BRIVIACT": 4.346983317038889, "BUPRENORPHINE": 1.3227818310698745, "BYDUREON": 0.8162420638815691, "CARBIDOPA": 4.340875059307174, "CELLCEPT": 0.5720836294348542, "CHAMPIX": 2.329649766128405, "CICLOSPORIN": 0.2697421776498915, "CIMZIA": 0.2540466860219876, "COMIRNATY": 1.0575596521468436, "COSENTYX": 0.5074612092853203, "CYMBALTA": 1.876811686716486, "ELIQUIS": 0.3481199124787084, "ESBRIET": 2.1489070888387083, "FAMPYRA": 1.6994933672100578, "FASLODEX": 1.1075493468549134, "FENTANYL": 0.5986804434651714, "FIRDAPSE": 5.087513095724264, "FYCOMPA": 2.383497799806398, "GARDASIL": 4.776761134435052, "HIZENTRA": 1.160977735209283, "HUMALOG": 0.7712416430952367, "IBRANCE": 2.218210411178181, "IBUPROFEN": 0.5839807113477564, "INLYTA": 2.319976162969021, "INVEGA": 6.01207201922781, "IRON": 4.890759305570806, "JARDIANCE": 0.3968620217840922, "KEPPRA": 3.186325860386709, "KEYTRUDA": 0.3778318660946162, "LANTUS": 0.6475050004306061, "LATUDA": 2.4351623363602144, "LEVETIRACETAM": 1.3279581376304306, "LYRICA": 2.2237478970065734, "MELATONIN": 3.1063297437196384, "MIDAZOLAM": 1.269382359835063, "MMRVAXPRO": 0.5339662572969588, "MODERNA": 0.4084175117184064, "NIMENRIX": 4.714902671182138, "NORVIR": 1.858568751371239, "NUCALA": 0.544269709083776, "OCRELIZUMAB": 2.1322792122852228, "OFEV": 0.9067710219986976, "OLANZAPINE": 2.293520671953554, "OPSUMIT": 1.0325417168938746, "PEGASYS": 1.8234259375781163, "PEGINTRON": 1.3410431815922088, "PLAVIX": 0.231928747856098, "ROTATEQ": 1.4430030130070923, "RUBRACA": 2.5809900352431043, "SHINGRIX": 0.3783434279610397, "SOLIRIS": 0.6033717509261174, "SPIKEVAX": 1.1246815932520366, "STELARA": 0.2645251664454119, "STIVARGA": 0.4678986014378868, "SUBOXONE": 0.7468957216699676, "SUTENT": 1.8559747789721937, "TAMIFLU": 0.7944061476233414, "TEDUGLUTIDE": 19.015954812781917, "TOZINAMERAN": 2.329664255593047, "TRULICITY": 0.6510660725565746, "VAXZEVRIA": 0.6366208717534693, "VIAGRA": 0.5216246581161732, "VIMPAT": 1.7974064772270453, "VOTRIENT": 0.5689927442096826, "XELJANZ": 0.7027335419939579, "XOLAIR": 0.7610866411796114, "XTANDI": 3.345165253333059, "ZOSTAVAX": 0.4477561514010033, "ZYPADHERA": 6.416259329163188, "ZYPREXA": 3.0484420696777907, "null": 0.8941702002897925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5867.json
index bb9b8e2196d..10a0bb9bddf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5867.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5867.json
@@ -1 +1 @@
-{"COMIRNATY": 3.2178071789352845}
\ No newline at end of file
+{"ADCIRCA": 136.82930560037616, "EXJADE": 16.70671098723399, "null": 0.4286798163716597}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5868.json
index 6a7155cd2be..7d9c464d19f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5868.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5868.json
@@ -1 +1 @@
-{"COMIRNATY": 2.146884941059276}
\ No newline at end of file
+{"null": 9.819460826248172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5869.json
index ada41c8ab42..fd695994e8f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5869.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5869.json
@@ -1 +1 @@
-{"SHINGRIX": 24.165679154344176, "TOZINAMERAN": 1.9481858989672196, "ZOSTAVAX": 47.09985954922732}
\ No newline at end of file
+{"ABACAVIR": 5.586330303197478, "ABASAGLAR": 0.301021663790857, "ABATACEPT": 1.2600831791409528, "ABILIFY": 2.604304732376006, "ACE": 1.7909516286114178, "ACLIDINIUM": 2.0391333021842586, "ACTOS": 0.6865531738231638, "ADALIMUMAB": 1.436684525271841, "ADCIRCA": 0.1736615078519227, "ADEMPAS": 0.3794177252461507, "ADENURIC": 0.9447166998319464, "AERIUS": 0.2475767796989845, "AFINITOR": 1.21318775347069, "AFLIBERCEPT": 4.509981388643912, "AIMOVIG": 1.199665147732628, "AJOVY": 2.7295588461459785, "ALEMTUZUMAB": 0.9401318486463928, "ALENDRONATE": 5.087392819013005, "ALIMTA": 0.2975785605379379, "ALISKIREN": 3.5441547102119166, "ALL": 0.6480262439333905, "AMINOSALICYLIC": 0.3225475144425937, "ANAKINRA": 0.7854166998609522, "ANORO": 0.3390926260109101, "ANTIHYPERTENSIVES": 4.718554198348741, "APIDRA": 0.5951128206433627, "APIXABAN": 3.8126757844309673, "APREMILAST": 0.7029908475257095, "APREPITANT": 0.3057419934926011, "APROVEL": 3.3278259770567447, "ARANESP": 0.8269747116252505, "ARAVA": 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0.3965703828178353, "REMICADE": 0.769536801054102, "REVATIO": 0.9130084542656292, "REVLIMID": 0.2591273503098948, "REYATAZ": 0.3715471288936898, "RIBAVIRIN": 0.2070217784011201, "RIBOCICLIB": 0.3558426927878415, "RINVOQ": 0.6646831180360356, "RISPERIDONE": 0.3103138689094405, "RITUXIMAB": 0.8230901671823626, "RIXATHON": 1.0258895750708086, "ROACTEMRA": 0.984545666293122, "ROSIGLITAZONE": 2.380579041389812, "RUBRACA": 0.3850593245174654, "RUCONEST": 0.4157148849894995, "RYBELSUS": 0.2326052379321762, "SAXENDA": 0.3984437951767171, "SCEMBLIX": 1.9497447632623612, "SHINGRIX": 0.2996511942728331, "SIFROL": 0.244533359125623, "SILDENAFIL": 0.7504524697055229, "SIMPONI": 0.7641519456757161, "SKYRIZI": 0.3527002737679427, "SOLIRIS": 1.5699031540281287, "SOMATROPIN": 0.6902737267382669, "SORAFENIB": 3.013407366915988, "SOVALDI": 0.1936829509942362, "SPIKEVAX": 0.4478478868728379, "SPINRAZA": 0.3161372142325573, "SPIRONOLACTONE": 0.8519827146966964, "SPRYCEL": 0.7498739005190277, "STALEVO": 0.3292810162114175, "STELARA": 0.6737765310834593, "STIVARGA": 4.748996929669808, "STRIBILD": 0.1730987763301864, "SUBOXONE": 0.4495464482780079, "SUFENTANIL": 1.211636624953588, "SUNITINIB": 8.780199481446322, "SUTENT": 4.11077621459278, "TACROLIMUS": 0.4736569457917569, "TAGRISSO": 0.2570842409732465, "TAMIFLU": 0.1791482501177164, "TASIGNA": 0.9669787813816784, "TEKTURNA": 4.070012386267104, "TELMISARTAN": 1.5672620643899602, "TERIFLUNOMIDE": 0.8953894532724734, "TERIPARATIDE": 0.8365951440407547, "TESTOSTERONE": 0.9259557747761789, "THALIDOMIDE": 0.3927516772815235, "THIOTEPA": 0.5588921240312296, "TICAGRELOR": 0.6882645955260785, "TIKOSYN": 1.7945603902584972, "TOCILIZUMAB": 0.4474119895865631, "TORISEL": 0.5644773181449058, "TOUJEO": 0.4394160149517329, "TOVIAZ": 0.9059076114769372, "TOZINAMERAN": 0.8491291118589265, "TRACLEER": 0.1707692710497313, "TRELEGY": 0.5450951076451518, "TREMFYA": 0.6149302807552269, "TRESIBA": 0.2562165909045081, "TRIUMEQ": 0.6175636192286519, 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1.8611172767552415, "null": 0.9645498769219982}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/587.json
index e5ff29ee3a6..b4b78a446f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/587.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/587.json
@@ -1 +1 @@
-{"AFINITOR": 1.408636505786204, "ARAVA": 3.723861259266066, "ARIPIPRAZOLE": 2.5827948639750606, "AVAMYS": 6.181626236964057, "BRINTELLIX": 2.4859069152567117, "COSENTYX": 1.2040535687269962, "CYMBALTA": 1.300874278114309, "ELLAONE": 9.00152179985779, "ESBRIET": 4.022294128035956, "FASENRA": 5.732178515833106, "GARDASIL": 1.6364036538295, "HUMIRA": 1.4768148373172176, "IBRANCE": 3.0988391054693385, "INSULIN": 22.9941844941446, "LYRICA": 1.4994992151562858, "MEPOLIZUMAB": 6.230200995265609, "METFORMIN": 12.024749024022574, "NUCALA": 2.5267073739393293, "PANTOPRAZOLE": 3.460504311852878, "PEGASYS": 2.1208590456183827, "PEGINTRON": 2.3135784099238754, "SAXENDA": 24.66198093097622, "SUTENT": 2.6855515473252405, "TRULICITY": 2.1474708143991514, "VAXZEVRIA": 1.277491287803154, "VOTRIENT": 1.7259419189019245, "ZOSTAVAX": 1.3187363390061286, "ZYPREXA": 2.127353234777491}
\ No newline at end of file
+{"null": 1.597310761985136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5870.json
index d68b6bf67da..f437947a28f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5870.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5870.json
@@ -1 +1 @@
-{"COMIRNATY": 1.869884835809562, "LYRICA": 1.6489870631591457, "METHOTREXATE": 1.0135269702459244, "NOT": 5.990997569429214, "RINVOQ": 9.899244154207254, "ROACTEMRA": 1.8741759876709985, "SHINGRIX": 40.93649928081029, "SIMPONI": 1.850504883356764, "STELARA": 1.123190602362552, "XELJANZ": 4.47859278818176, "ZOSTAVAX": 102.7002753113882}
\ No newline at end of file
+{"null": 3.0368512204162816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5871.json
index 416ffcb6f16..63a16b98d31 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5871.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5871.json
@@ -1 +1 @@
-{"COMIRNATY": 2.801471198401816, "TOZINAMERAN": 2.06410230311864, "VAXZEVRIA": 1.5191169585506945}
\ No newline at end of file
+{"AVANDIA": 28.971509755519406, "null": 1.007369280660236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5872.json
index aa7562d7dce..047d5efb919 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5872.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5872.json
@@ -1 +1 @@
-{"COMIRNATY": 2.1418821255626903}
\ No newline at end of file
+{"ADALIMUMAB": 0.1560642661551315, "ALISKIREN": 3.102002037349749, "APROVEL": 5.691066606938431, "ARANESP": 0.8915803935007067, "ARAVA": 0.1293259448703503, "AUBAGIO": 1.0537560128970656, "AVASTIN": 0.961800303294118, "BETMIGA": 14.94899623366564, "BRIDION": 5.792686233237613, "BRILIQUE": 1.2396975584648708, "BRINTELLIX": 1.387875285644966, "CHAMPIX": 0.5936876997347831, "CICLOSPORIN": 0.6509502182666321, "CIMZIA": 0.1959912210990362, "CLOPIDOGREL": 0.5179289337095493, "COAPROVEL": 8.958691365123826, "COMIRNATY": 1.5735846245662912, "CYMBALTA": 2.5303845022633578, "DARZALEX": 1.7776701243159791, "ELIQUIS": 0.5681099833637705, "EXFORGE": 4.593193105475947, "EYLEA": 1.0358677059380152, "FENTANYL": 0.9384944553878884, "FORSTEO": 1.4910364729274934, "FOTIVDA": 15.13123134719624, "HARVONI": 1.5163282800588258, "ICLUSIG": 2.9854202902178293, "INLYTA": 4.1559687576192905, "JANUMET": 1.2516395898088866, "JANUVIA": 0.4414713911977325, "JARDIANCE": 0.2507569146834659, "KEPPRA": 0.476794518902746, "KEYTRUDA": 0.2927554375539276, "KYPROLIS": 7.544241445533405, "LANTUS": 0.3221080970313899, "LENVIMA": 6.008694766639326, "LIXIANA": 1.7275199937733474, "MICARDIS": 10.889220621899009, "MICARDISPLUS": 13.864332829667823, "MIMPARA": 4.509104610279337, "MODERNA": 0.7872126156844231, "NEXAVAR": 1.7512371533723716, "OFEV": 0.8889743525541713, "PEGASYS": 0.1221259953939462, "PLAVIX": 0.227378921447401, "PRIVIGEN": 1.7488214080925564, "PROPRANOLOL": 3.5960673049710707, "RASILEZ": 10.961562570895266, "ROACTEMRA": 3.480866678477814, "SOLIRIS": 1.7509509083313637, "SPIKEVAX": 0.6538713413501872, "STELARA": 0.4939730794318764, "STIVARGA": 1.8283639170819357, "SUTENT": 1.7186521850576966, "TELMISARTAN": 5.356696146564699, "TOZINAMERAN": 0.9924323201290198, "VAXZEVRIA": 0.5895488029947518, "VIAGRA": 0.7248824188342763, "VOTRIENT": 4.912660789291862, "XELJANZ": 0.1863494268828433, "XOLAIR": 0.380808274333519, "XTANDI": 0.5885637758217859, "null": 1.087891402840846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5873.json
index 05679787881..6e0aeaed46c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5873.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5873.json
@@ -1 +1 @@
-{"COMIRNATY": 5.125084534539589, "CYMBALTA": 3.824059703848672, "ELIQUIS": 3.165873003655279, "SPIKEVAX": 1.2932423859501174, "VAXZEVRIA": 4.920479557366775}
\ No newline at end of file
+{"COMIRNATY": 0.7281634517366002, "SPIKEVAX": 0.9737199602815916, "TOZINAMERAN": 0.9427475551191572, "VAXZEVRIA": 0.4598918340201941, "null": 1.026601474185438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5874.json
index 368aaa122a6..e65bbf0ba74 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5874.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5874.json
@@ -1 +1 @@
-{"ABACAVIR": 5.394833940515004, "ABILIFY": 3.656175965973194, "ATAZANAVIR": 36.33223870588911, "BUPIVACAINE": 89.29806148768498, "CICLOSPORIN": 1.859676225037296, "CRIXIVAN": 21.53586652576077, "ENFUVIRTIDE": 288.0299812836236, "GARDASIL": 1.1130207167390105, "HUMIRA": 5.966586871166773, "KEYTRUDA": 2.5570750976371146, "PEMBROLIZUMAB": 8.032282111595299, "SAQUINAVIR": 798.8004375898169, "null": 1.0991614674538857}
\ No newline at end of file
+{"CICLOSPORIN": 6.974744030350709, "null": 1.976203142286078}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5875.json
index 2dacee7fcf9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5875.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5875.json
@@ -1 +1 @@
-{"FENTANYL": 159.00956045926398, "null": 2.387538094559576}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5876.json
index 812f5d89163..c986036fd46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5876.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5876.json
@@ -1 +1 @@
-{"GARDASIL": 2.504018289459586, "HEXYON": 109.67758439435184, "MMRVAXPRO": 4.972029947016519, "NIMENRIX": 9.797976447567253, "OLANZAPINE": 4.452592573666275, "ZYPREXA": 4.568121020654727, "null": 5.5302567009443}
\ No newline at end of file
+{"AVANDAMET": 27.68616959106914, "AVANDIA": 30.99793316451888, "COMIRNATY": 0.3749202213092603, "ELIQUIS": 1.6423359518308136, "ENTRESTO": 12.308155954952712, "FENTANYL": 3.0671916125659267, "JANUVIA": 5.2133195902605936, "ONGLYZA": 89.10909366480809, "SUBOXONE": 3.593636930279242, "VAXZEVRIA": 0.0900196244648222, "ZOSTAVAX": 7.462824375071254, "null": 0.8374642913890368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5877.json
index 97e00d08841..becd3d58a26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5877.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5877.json
@@ -1 +1 @@
-{"ATAZANAVIR": 24.38041814153666, "BIKTARVY": 19.559388367292687, "CELLCEPT": 9.029254075926865, "CICLOSPORIN": 4.641848162781707, "MYCOPHENOLATE": 31.335685602671106}
\ No newline at end of file
+{"ATRIPLA": 5.815055212860129, "ZOSTAVAX": 32.105547026277115, "null": 0.6340347648828809}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5878.json
index 3d8f2fcc203..86591c38f31 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5878.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5878.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 56.747105827895965, "null": 3.555003800928013}
\ No newline at end of file
+{"COMIRNATY": 0.6538608482299999, "SPIKEVAX": 0.3262718747768475, "VAXZEVRIA": 0.6181950578951769, "null": 0.7665926802860421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5879.json
index fd239fd93d0..3d16b2d3ad4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5879.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5879.json
@@ -1 +1 @@
-{"KEPPRA": 4.9864507668882805, "PEGASYS": 1.7150418931700109, "VIAGRA": 19.319876776397145, "VIGABATRIN": 206.5678709662796, "null": 1.852231509656174}
\ No newline at end of file
+{"ABILIFY": 2.4085860005435054, "ALIMTA": 1.27431617831495, "ARIPIPRAZOLE": 0.7794504205212174, "BRINTELLIX": 0.7261417532997446, "CANCIDAS": 5.335012905184868, "CELLCEPT": 1.18929474383296, "CLOPIDOGREL": 1.1982994302647798, "COMIRNATY": 0.6267200755381299, "COMTAN": 4.482289071198148, "COTELLIC": 4.8817078958393765, "CUBICIN": 3.183789971470352, "CYMBALTA": 0.4987934855562079, "DEXAMETHASONE": 0.8932881262901121, "DEXDOR": 67.87160182829832, "DEXMEDETOMIDINE": 11.327580015104171, "ENTACAPONE": 7.379196534772826, "FENTANYL": 2.202181793829046, "FLEBOGAMMA": 18.2845897031136, "FORSTEO": 0.5758980562175993, "GARDASIL": 0.3429347702507529, "IBUPROFEN": 1.554852804149925, "INCIVO": 3.2305144162995467, "KALETRA": 1.341024002128602, "KEPPRA": 0.3957304942242717, "KEYTRUDA": 0.5236788507817431, "KIOVIG": 15.947944483501754, "LEMTRADA": 3.88099883898254, "MEKINIST": 5.233498759087492, "METHOTREXATE": 0.5127288085010292, "MIDAZOLAM": 6.093990597904907, "MMRVAXPRO": 1.3089253964364609, "NIMENRIX": 2.214580913911386, "OLANZAPINE": 9.634391605150622, "OPDIVO": 0.8924272441823605, "PEGASYS": 0.3437428159666945, "PEGINTRON": 0.7792798231102384, "PRIVIGEN": 7.6045744899097505, "SHINGRIX": 0.6267336563034788, "SIMPONI": 0.3921604034566618, "SPIKEVAX": 0.3163485927327352, "SPINRAZA": 2.1185299658147625, "STIVARGA": 2.5571918749185523, "SUTENT": 0.2991879812163387, "TAMIFLU": 0.8533852518533526, "TOZINAMERAN": 0.2321054375451816, "VAXZEVRIA": 0.3906360623508302, "ZYPREXA": 3.820736865382058, "null": 2.146625730467475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/588.json
index c7a4da19eff..08b95c68e43 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/588.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/588.json
@@ -1 +1 @@
-{"null": 2.037812422706561}
\ No newline at end of file
+{"COMIRNATY": 0.1176422164462883, "INCIVO": 156.10212426211726, "JARDIANCE": 2.768747870739882, "PEGASYS": 28.45281085338077, "PEGINTERFERON": 67.68052608117532, "PEGINTRON": 3.9272887637429887, "RIBAVIRIN": 9.494457793957295, "VAXZEVRIA": 0.0876701448091987, "null": 1.3424821761314087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5880.json
index 50f144333e5..16d5755a3af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5880.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5880.json
@@ -1 +1 @@
-{"null": 1.125430266136171}
\ No newline at end of file
+{"DEXAMETHASONE": 2.4566234150891813, "DEXMEDETOMIDINE": 106.40464124789246, "FENTANYL": 87.35351573141122, "METHOTREXATE": 4.154407195791473, "MIDAZOLAM": 47.17248476201075, "SUFENTANIL": 133.87630810898844, "ZYPREXA": 3.5785457210063467, "null": 3.148520601823473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5881.json
index 92b1aca746f..8775e2c0d1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5881.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5881.json
@@ -1 +1 @@
-{"null": 1.0041057705130856}
\ No newline at end of file
+{"AFINITOR": 0.2241626614706026, "AIMOVIG": 0.8871695655142666, "ALEMTUZUMAB": 7.285169440682011, "ALIMTA": 0.6206755632949672, "ARAVA": 0.0500337256511599, "ATEZOLIZUMAB": 8.25653582889938, "AUBAGIO": 0.7621876784715269, "AVELUMAB": 17.65920078636035, "AXITINIB": 6.023734656797981, "BAVENCIO": 14.327401158905998, "BETAFERON": 2.673408447388397, "BYDUREON": 0.413123495115396, "CABOMETYX": 4.98235930642546, "CELLCEPT": 0.4516269389973212, "CHAMPIX": 1.047978501173097, "CIRCADIN": 3.968890502049475, "COMIRNATY": 0.2976134222120585, "COSENTYX": 0.4377913148224813, "DABRAFENIB": 2.131478155385784, "DAPAGLIFLOZIN": 3.0555622525164186, "DEXAMETHASONE": 0.8080747595010405, "ELIQUIS": 0.264624416482848, "EMPAGLIFLOZIN": 6.120062034157296, "ENTRESTO": 0.6273636862753229, "EPIVIR": 2.349197085017803, "ERLEADA": 1.5632371161632093, "FORSTEO": 0.3081339474413506, "GALVUS": 1.5159250274330671, "GARDASIL": 0.5365178157734707, "GLYCOPYRRONIUM": 3.85390579751219, "HARVONI": 0.8890743142127906, "HUMALOG": 0.3029068480709585, "ICLUSIG": 1.6306084118674562, "INCIVO": 0.6308473751076231, "INLYTA": 5.268592704605744, "INTERFERON": 10.790047126681598, "INTRONA": 9.335243087282992, "IPILIMUMAB": 14.383006757701027, "JARDIANCE": 1.766638786908724, "KALETRA": 0.5896382371467436, "KEPPRA": 0.2259787911537755, "KEYTRUDA": 16.50293212683646, "LANTUS": 0.5245586988319428, "LEMTRADA": 30.2312216890142, "LENVIMA": 2.969415514403733, "LIBTAYO": 7.853787427306609, "MICARDIS": 0.5606032726183928, "MULTAQ": 6.798906501024758, "NEXAVAR": 0.8687544792055206, "NIVOLUMAB": 13.733024371330457, "NUCALA": 0.3633944345554999, "OPDIVO": 16.87828333167245, "OPSUMIT": 0.718586146139806, "PACLITAXEL": 1.688545600803815, "PEGASYS": 6.010583766736021, "PEGINTERFERON": 5.789749410355004, "PEGINTRON": 8.830731809385144, "PEMBROLIZUMAB": 7.739652271170485, "PIOGLITAZONE": 57.898074885963794, "PLAVIX": 0.1333418657194237, "PROPRANOLOL": 4.198488588792926, "REBETOL": 7.27997098558161, "RIBAVIRIN": 1.0105475476562011, "SAXENDA": 0.7346587397052278, "SHINGRIX": 0.2223318867379511, "SIMPONI": 0.5162153621089611, "SPIKEVAX": 0.1702237883683783, "SPIRONOLACTONE": 1.7054215586341257, "STELARA": 0.6855497616974445, "STIVARGA": 1.1227595740712653, "SUTENT": 2.77201306962794, "TASIGNA": 1.8719741375719496, "TOZINAMERAN": 0.354159147228641, "TREMFYA": 0.7518697774962284, "TRUVADA": 0.0600642699300172, "VAXZEVRIA": 0.1137185421842919, "VICTOZA": 0.7804523079461355, "VOTRIENT": 1.5121735548542348, "XELJANZ": 0.1684579054721984, "XOLAIR": 0.1762671986481871, "YERVOY": 3.931229555385353, "ZOSTAVAX": 0.4395991437336364, "ZYPREXA": 0.3315058997502316, "null": 1.9939080151130455}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5882.json
index 958942651d2..06233fef153 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5882.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5882.json
@@ -1 +1 @@
-{"null": 1.4952445862083286}
\ No newline at end of file
+{"ABILIFY": 0.9273270667672232, "ARIPIPRAZOLE": 6.159260397734927, "BUPRENORPHINE": 2.3929454086732624, "COMBIVIR": 3.0766469571252038, "COMIRNATY": 0.200377719589624, "COMTAN": 11.321824416896892, "CYMBALTA": 1.60589887274926, "EPIVIR": 6.0388137392567, "FENTANYL": 2.2549908895269413, "GARDASIL": 1.6818157838770469, "IBUPROFEN": 3.195441236438478, "INFANRIX": 11.751743295801267, "KEPPRA": 3.343986264894684, "KETOCONAZOLE": 29.58478134540618, "MIDAZOLAM": 8.425348648457915, "MMRVAXPRO": 7.869019385311396, "OCEAN": 158.83610522990733, "OLANZAPINE": 7.773155400848025, "RISPERIDONE": 6.812703460666097, "SPIKEVAX": 0.1237990056783755, "VAXZEVRIA": 0.0693747092309556, "ZYPREXA": 3.079811398520228, "null": 3.863781612589656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5883.json
index 6d07c5f9846..1131e68fdd6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5883.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5883.json
@@ -1 +1 @@
-{"null": 1.5376831920133922}
\ No newline at end of file
+{"null": 6.5697319713125335}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5884.json
index 4ce98c9843e..c19920b1740 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5884.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5884.json
@@ -1 +1 @@
-{"HUMALOG": 1.0892482021102332, "PEGASYS": 4.439784482206279, "PEGINTERFERON": 6.866297589043155, "PEGINTRON": 7.8836263184468995, "SHINGRIX": 1.904012435522828, "SILDENAFIL": 75.23133853382573, "VIAGRA": 115.47809232654626, "ZOSTAVAX": 2.229958495541152}
\ No newline at end of file
+{"ACE": 255.74431146299892, "BETMIGA": 25.58645950238521, "COMIRNATY": 0.2367690539445044, "CYMBALTA": 4.834773217360102, "DEXAMETHASONE": 4.902921887304403, "FAMPYRA": 12.440613729835611, "GARDASIL": 3.698041584363723, "MICARDIS": 12.760128558653369, "OXYBUTYNIN": 38.76044063080097, "SPIKEVAX": 0.2244985407742862, "TOVIAZ": 20.09643440232842, "VAXZEVRIA": 0.2650510731339831, "ZOSTAVAX": 19.949665617823587, "null": 1.1799366561284943}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5885.json
index db2dcae05f9..baea250b270 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5885.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5885.json
@@ -1 +1 @@
-{"null": 1.7699517587271436}
\ No newline at end of file
+{"ADALIMUMAB": 0.4090944333648326, "AFINITOR": 1.2976932449102714, "ALEMTUZUMAB": 4.088262904753532, "ALIMTA": 6.236898858634018, "ARAVA": 0.1249310335728943, "ASPARAGINASE": 5.421282670953528, "AUBAGIO": 1.6730864033213666, "AVASTIN": 1.819388504786772, "AVELUMAB": 12.68088634569746, "AXITINIB": 12.060992446014156, "AZATHIOPRINE": 1.441109560278524, "BIKTARVY": 1.4053437527944086, "BUSULFAN": 1.267903718262282, "CABOMETYX": 5.465354651768304, "CAELYX": 2.337656610588982, "CAPECITABINE": 3.9010831884884505, "CELLCEPT": 1.286898800318412, "CICLOSPORIN": 1.515530873401984, "CLOPIDOGREL": 0.3510746425585539, "COMIRNATY": 0.0472853986635869, "COSENTYX": 0.354397627301356, "COTELLIC": 5.8447392057766345, "CUBICIN": 4.715645780029284, "CYTARABINE": 3.7709309891317626, "DEXAMETHASONE": 2.4049645026094355, "DOCETAXEL": 1.0743142025597237, "ELIQUIS": 0.2610627372448728, "ESBRIET": 1.2678933168310669, "ESMYA": 11.116753889695987, "EXJADE": 2.778442021269, "EXVIERA": 9.198437606846044, "GAZYVARO": 5.860827136769324, "HALAVEN": 10.720124075044732, "HERCEPTIN": 4.0855247386006255, "IBRANCE": 2.3676352241388594, "IBUPROFEN": 1.272421128312494, "ICLUSIG": 2.419927285511357, "INLYTA": 4.049740849509499, "IPILIMUMAB": 13.398479899659156, "IRESSA": 6.531480852162676, "IRINOTECAN": 10.540164607175209, "JANUMET": 0.9305923240766678, "KAFTRIO": 14.8060837661288, "KALETRA": 11.52002020087891, "KEPPRA": 1.6107964515070874, "KEYTRUDA": 2.32853674668975, "KISQALI": 18.154727766307488, "LEVETIRACETAM": 3.644663696860511, "LEVOFLOXACIN": 1.9578411829666795, "LOPINAVIR": 8.076201285937115, "MEKINIST": 1.407784994620553, "METHOTREXATE": 3.768726715925843, "MULTAQ": 2.3460573106831637, "NEXAVAR": 2.3681407466998494, "NOXAFIL": 9.717181600805674, "NPLATE": 1.5323326654592568, "OFEV": 7.158299680220993, "OLANZAPINE": 1.6127022047179371, "OPDIVO": 2.152801648897868, "PAZOPANIB": 7.294641958004463, "PEGASYS": 0.4203859347479078, "PEMBROLIZUMAB": 9.422480830953967, "PEMETREXED": 6.8597886032104185, "REMDESIVIR": 37.78213428877549, "RIBOCICLIB": 14.751527832335034, "RINVOQ": 1.56547331511846, "ROACTEMRA": 3.757590643833084, "RUBRACA": 5.010802015573565, "SPIKEVAX": 0.021406715611379, "STIVARGA": 2.8283745600621306, "SUTENT": 0.4735185575462062, "TAMIFLU": 1.453334342913589, "TEMOZOLOMIDE": 7.499914540658484, "TOZINAMERAN": 0.0586694936530208, "TRABECTEDIN": 61.68296180850008, "TRACLEER": 1.4584528338551783, "TRIUMEQ": 7.174762543246094, "VAXZEVRIA": 0.0372050095240055, "VEKLURY": 52.94321098013379, "VFEND": 1.0668836023578965, "VORICONAZOLE": 6.225721462704013, "VOTRIENT": 8.765312647622824, "XALKORI": 5.77310332854318, "YERVOY": 6.916256578616816, "YESCARTA": 4.145280065610461, "YONDELIS": 26.536317994353084, "ZEPATIER": 11.505857133645623, "ZOSTAVAX": 0.3558610585614034, "null": 1.170931595416189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5886.json
index cf64eac2fca..6bf9dd6966d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5886.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5886.json
@@ -1 +1 @@
-{"BEDAQUILINE": 27.34892358315133, "COMBIVIR": 15.585757400271092, "PEGINTRON": 5.08671583400806, "VIAGRA": 24.46343675201418, "null": 1.1238830385267575}
\ No newline at end of file
+{"CICLOSPORIN": 17.86066688461875, "COMIRNATY": 0.0770770895973054, "null": 4.678192907875999}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5887.json
index 7292bc6f289..348e2a8e1cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5887.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5887.json
@@ -1 +1 @@
-{"null": 5.172121072992665}
\ No newline at end of file
+{"ABACAVIR": 5.814932666104827, "ABILIFY": 0.8509107457496172, "ADENURIC": 9.957229614831288, "AFINITOR": 6.690632217436224, "APIDRA": 1.3624882241218472, "ASPARAGINASE": 39.53357680926413, "ATAZANAVIR": 6.206320518524291, "ATRIPLA": 0.3568662761869052, "AVANDIA": 0.7927174057892509, "AZATHIOPRINE": 2.820994791881923, "BIKTARVY": 2.345542398288093, "BYETTA": 3.46721700548565, "CELLCEPT": 1.1802684989388106, "CICLOSPORIN": 1.4286688696758578, "COMBIVIR": 22.572677471226296, "COMIRNATY": 0.0158756122135579, "COSENTYX": 2.456376269313804, "CRIXIVAN": 78.43224785587607, "CYMBALTA": 0.3123501628896222, "CYTARABINE": 2.975052763041889, "DEXAMETHASONE": 4.135981195707384, "EFAVIRENZ": 4.035476968333149, "EMTRICITABINE": 8.325414961562897, "EMTRIVA": 19.27069761347895, "EPIVIR": 51.79666303790715, "FASTURTEC": 56.7835595759765, "FORTOVASE": 80.38347635221086, "FORXIGA": 1.2453904395417417, "ICLUSIG": 5.53918065904896, "INCIVO": 3.9926395481990777, "INDINAVIR": 28.139140514324016, "INVIRASE": 119.9334095543476, "ISENTRESS": 5.457587187879199, "JAKAVI": 3.614439892547741, "JANUVIA": 2.11199929218251, "JARDIANCE": 0.7004461209395362, "KALETRA": 57.19398421371701, "LAMIVUDINE": 16.378838925631023, "LANTUS": 0.4383600527497814, "LOPINAVIR": 11.904320162033985, "LYRICA": 1.0041647003349994, "METHOTREXATE": 1.6158545330797431, "NEVIRAPINE": 11.968615933076451, "OLANZAPINE": 5.820213556262758, "ONCASPAR": 68.31196412915445, "PEGASPARGASE": 55.46322503486626, "PEGASYS": 1.2196747247388784, "PEGINTRON": 0.8672785439242318, "RAPAMUNE": 8.736339237483916, "RINVOQ": 1.895863918329233, "ROACTEMRA": 2.671053321526618, "STELARA": 1.051617146980207, "SUTENT": 1.4369728383816065, "TASIGNA": 2.074864431449301, "TEMSIROLIMUS": 37.08302601852363, "TORISEL": 11.689391749696656, "ZOSTAVAX": 1.4165904084079082, "ZYPREXA": 10.606737216144456, "null": 0.6817514474125554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5888.json
index 8eee8fbd8f9..a393f4f31bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5888.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5888.json
@@ -1 +1 @@
-{"ZOSTAVAX": 5.5729332034412495, "null": 1.5363680297848727}
\ No newline at end of file
+{"AVANDIA": 3.912040721943266, "COMIRNATY": 0.3363816936377348, "LEVETIRACETAM": 22.06533167375348, "SPIKEVAX": 0.2214090765719878, "null": 1.5546097505951184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5889.json
index 9a9911abeae..af1085e469c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5889.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5889.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 3.10922594352912, "AMIKACIN": 8.628884490105358, "AMINOSALICYLIC": 7.993482644255071, "AUBAGIO": 16.36978572389746, "BEDAQUILINE": 13.441853436674988, "BETAFERON": 15.885276611415652, "CIMZIA": 2.067653581497214, "COMBIVIR": 4.191856692675621, "ENTYVIO": 1.396301841259732, "GARDASIL": 6.166319942328212, "HUMIRA": 1.573531254570598, "INTRONA": 7.712711717318518, "IPILIMUMAB": 6.291091398036157, "KALETRA": 1.6283813384203587, "KESIMPTA": 10.21881080861654, "KEYTRUDA": 3.257634972181272, "KYMRIAH": 2.4056935949643994, "LEMTRADA": 5.323278433489317, "LEVOFLOXACIN": 1.488505410636438, "MAVENCLAD": 12.2719335947408, "MEKINIST": 1.7588906953512915, "METHOTREXATE": 1.217592837881572, "PEGASYS": 2.159315863619944, "PEGINTRON": 5.74878954844395, "PLEGRIDY": 5.270160415198022, "REBETOL": 6.373349113214562, "ROACTEMRA": 1.6527643946075192, "SAXENDA": 1.667217135472968, "SHINGRIX": 1.2542805944248647, "SIMPONI": 2.936252398692796, "STELARA": 1.415157605007669, "TASIGNA": 1.271546056269187, "TOZINAMERAN": 1.1133928110525482, "TWINRIX": 12.203871933097796, "VFEND": 5.216255483140998, "VIAGRA": 3.170918457452134, "XOLAIR": 1.0378115720738854, "ZOSTAVAX": 1.1424798837616252}
\ No newline at end of file
+{"VORICONAZOLE": 473.5437946723953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/589.json
index 19960cf7c08..056e5b4282b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/589.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/589.json
@@ -1 +1 @@
-{"null": 8.45167466525154}
\ No newline at end of file
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5890.json
index 3ff1c8d1928..fa63acb3950 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5890.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5890.json
@@ -1 +1 @@
-{"COMBIVIR": 11.184288860664696, "FENTANYL": 2.9427098556537303, "PEGASYS": 2.4748696296274693, "PEGINTERFERON": 9.950603839118072, "PEGINTRON": 8.783995469735185, "TELMISARTAN": 42.39028228996898, "VFEND": 4.908754258348037, "VIAGRA": 4.502740865463051, "null": 1.5851277602675364}
\ No newline at end of file
+{"null": 1.3183814393892817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5891.json
index 8981c2a21d7..016eb23e7de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5891.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5891.json
@@ -1 +1 @@
-{"JETREA": 2182.0966030865507, "VIGABATRIN": 3883.8639835737167}
\ No newline at end of file
+{"COMIRNATY": 0.2862730055812162, "null": 1.401232239230152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5892.json
index 802c4d5d2b6..230eb3bc0ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5892.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5892.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 42.92551807710531, "SUBOXONE": 64.07084743437848, "null": 2.767046335723498}
\ No newline at end of file
+{"COMIRNATY": 1.2677451692426729, "null": 1.3353631575089848}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5893.json
index 73421f1ada9..ff5c91a68d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5893.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5893.json
@@ -1 +1 @@
-{"null": 6.946393816732602}
\ No newline at end of file
+{"BRILIQUE": 8.391195363188555, "CELLCEPT": 8.244987901471195, "CICLOSPORIN": 1.6528896806674505, "COAPROVEL": 11.596833609948632, "COMBIVIR": 5.458660354075048, "COMIRNATY": 0.0591600362628979, "DAPAGLIFLOZIN": 52.02265574909392, "ELIQUIS": 0.4485812242691561, "ENTRESTO": 1.8340138612387795, "EXFORGE": 3.006942678953681, "FORSTEO": 2.276734074500842, "INCIVO": 14.17020391769327, "IRBESARTAN": 5.005433905653601, "JAKAVI": 3.1068183740292614, "KEYTRUDA": 1.0830064165944504, "LEVOFLOXACIN": 1.523453314056869, "METHOTREXATE": 1.3754374737840052, "MICARDIS": 4.240958326105247, "MICARDISPLUS": 56.98978011291496, "NEXAVAR": 2.3850677568379104, "OLANZAPINE": 3.7928071018760345, "PEGASYS": 1.6988007859304124, "PEGINTERFERON": 23.365808676321887, "PEGINTRON": 24.50673824102144, "REBETOL": 12.16986048262845, "SUTENT": 1.6388601446282849, "null": 1.3200047141459357}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5894.json
index a9c2b13dec8..022f2821f9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5894.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5894.json
@@ -1 +1 @@
-{"null": 1.671936358066331}
\ No newline at end of file
+{"BRILIQUE": 2.372300037540408, "CHAMPIX": 2.2273284450188022, "COMIRNATY": 1.477225421539896, "CYMBALTA": 0.7972527814946622, "DEXAMETHASONE": 0.8979128754079034, "FASENRA": 1.7966704280393777, "FENTANYL": 1.550426261381788, "GARDASIL": 10.850281370163048, "HYDROCORTISONE": 2.1366673032336387, "IBUPROFEN": 1.2633782748040157, "IRON": 6.859741536361875, "JARDIANCE": 3.0342327881176594, "KEPPRA": 0.8309443475129416, "LATUDA": 3.0548652769830373, "MIDAZOLAM": 1.956047881472704, "MMRVAXPRO": 0.6334398563174316, "NIMENRIX": 1.7955847577132846, "OLANZAPINE": 1.006032559459747, "PEGASYS": 0.5741378067302321, "PEGINTRON": 0.7589212571808942, "PLAVIX": 0.5016896222575074, "SPIKEVAX": 0.6818482723352312, "SUBOXONE": 0.6727892534159584, "TOZINAMERAN": 1.198165336851145, "TWINRIX": 2.877268554592895, "VAXZEVRIA": 0.5892975387634761, "XOLAIR": 4.153475508116762, "ZYPREXA": 1.244291761214949, "null": 1.4458545579447046}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5895.json
index 5f8aa117859..e2135da9fec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5895.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5895.json
@@ -1 +1 @@
-{"COVID19": 3.211326033890387, "TOZINAMERAN": 1.959918330220516, "VAXZEVRIA": 1.2533202971313198}
\ No newline at end of file
+{"COMIRNATY": 0.2914756553143169, "CYMBALTA": 4.924578946749222, "SPIKEVAX": 0.4063291238087846, "VAXZEVRIA": 0.2203977770697632, "null": 2.063261437569512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5896.json
index b6a233793ce..f8ac2200cdb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5896.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5896.json
@@ -1 +1 @@
-{"ABACAVIR": 2.075965350732973, "ACLIDINIUM": 5.240636219464246, "ADALIMUMAB": 7.326698403738829, "ALIGN": 108.67658809148702, "ALIMTA": 2.75204136774328, "AMINOSALICYLIC": 62.15940815585522, "ANORO": 5.600641232710296, "AVAMYS": 33.38011770190547, "AZATHIOPRINE": 2.4290633647920425, "BEXTRA": 12.170827291552945, "BUDESONIDE": 40.83840925748972, "BUSULFAN": 1.0651969881198768, "CAPECITABINE": 1.033499723965418, "CASPOFUNGIN": 5.516021599530959, "CELLCEPT": 1.1565821284662814, "CIMZIA": 1.0441257655725256, "COSENTYX": 8.810117655092354, "CYTARABINE": 1.5120411477748852, "DACLATASVIR": 7.061174146273633, "DELAMANID": 10.854896403765474, "DEXAMETHASONE": 1.1722817181871108, "DUORESP": 16.35545172849498, "ENTYVIO": 1.7323561396448457, "EPIVIR": 4.697492849660551, "GANCICLOVIR": 5.375922212651754, "INCIVO": 3.4666639284750143, "INCRUSE": 4.793885048519384, "JORVEZA": 97.95356823430126, "KALETRA": 2.0491084178176253, "LAMIVUDINE": 2.0457059839534777, "MEPOLIZUMAB": 1.5176948138477222, "METHOTREXATE": 1.5234066557116086, "NEULASTA": 2.0160950685816665, "NORVIR": 3.1838893230475063, "NUCALA": 2.952608828328524, "OPDIVO": 1.0914693483994882, "PEGASYS": 1.0380164544160628, "PEGINTERFERON": 2.384868751403672, "PREGABALIN": 17.107783150326775, "RELVAR": 16.899030218835332, "RINVOQ": 2.5810019956608703, "SIMPONI": 1.538272795112576, "TRELEGY": 7.311876537172459, "UMECLIDINIUM": 9.476668531196724}
\ No newline at end of file
+{"null": 0.8438068151165871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5897.json
index b307c3db30d..4152edfcf79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5897.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5897.json
@@ -1 +1 @@
-{"null": 1.3737295251571595}
\ No newline at end of file
+{"HYDROXOCOBALAMIN": 12004.371426589903, "null": 2.0689680189058968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5898.json
index 5783a535626..5db20dc5145 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5898.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5898.json
@@ -1 +1 @@
-{"COMIRNATY": 8.441672520054388}
\ No newline at end of file
+{"null": 2.846137987720282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5899.json
index d32c78ae862..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5899.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5899.json
@@ -1 +1 @@
-{"COVID19": 2.533624472913047, "VAXZEVRIA": 2.4642960792907016}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/59.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/59.json
index 0210928f76d..f23cdf319a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/59.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/59.json
@@ -1 +1 @@
-{"AMIKACIN": 23.63360683482409, "CICLOSPORIN": 1.139748794147006, "CIMZIA": 1.921306003622615, "COSENTYX": 4.36418901000244, "ENBREL": 1.5776049833459913, "HUMALOG": 2.423970573245167, "JARDIANCE": 4.780448596184982, "METHOTREXATE": 2.2822416028897563, "NEXAVAR": 2.258015054011106, "PEGASYS": 3.1456478539677666, "PEGINTRON": 1.7202642512240935, "ROACTEMRA": 16.375334716636576, "SIMPONI": 6.587175574871973, "SOMATROPIN": 27.31409671249371, "STELARA": 2.3209900731435438, "SUBOXONE": 2.8444969163870018, "SUTENT": 1.6809305295315675, "XELJANZ": 2.5028862684074333, "ZOSTAVAX": 1.5639126245218675, "ZYPADHERA": 8.907174373435073}
\ No newline at end of file
+{"COMIRNATY": 4.497464173875331, "SPIKEVAX": 3.478635973324953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/590.json
index 301708045d1..51ce01c9af8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/590.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/590.json
@@ -1 +1 @@
-{"null": 3.791598180341608}
\ No newline at end of file
+{"null": 1.145626223782917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5900.json
index 047309c2b56..1825b2ce5f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5900.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5900.json
@@ -1 +1 @@
-{"null": 2.531466042797645}
\ No newline at end of file
+{"null": 3.016159131874084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5901.json
index 4b6ab2fb0a5..1b654d4b5c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5901.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5901.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.739430219706182, "AERIUS": 3.320583462891775, "CABOMETYX": 1.455681353890873, "CHLORHEXIDINE": 2.751138203065422, "CIMZIA": 1.080145477425531, "FORSTEO": 1.0897428204868342, "INLYTA": 2.357684248620034, "ONCASPAR": 3.657221832604946, "QUTENZA": 4.59956394822805, "RELVAR": 3.715956572333219, "SUBOXONE": 1.0661711115622536, "SUTENT": 6.408973951329068, "TELMISARTAN": 5.600585268935812, "TRELEGY": 3.477395642316657, "VOTRIENT": 1.0672887991674107, "null": 3.334646751470425}
\ No newline at end of file
+{"ADCIRCA": 21.72081284231022, "ADEMPAS": 17.56384877407431, "ALEMTUZUMAB": 3.168429663414219, "AMBRISENTAN": 17.603873303054794, "ARANESP": 3.3277970112457638, "AVANDIA": 6.426760338457346, "BUMETANIDE": 9.80238224509852, "BYETTA": 1.2672142009571128, "CASPOFUNGIN": 8.447805013972856, "CELLCEPT": 1.5089015210409342, "CICLOSPORIN": 2.0966487757510137, "COMIRNATY": 0.0362788280469555, "CYTARABINE": 3.5097280343200747, "DARZALEX": 2.6873569924139105, "DASATINIB": 27.36786162335604, "DEXAMETHASONE": 2.9354681123177797, "ELIQUIS": 0.9202046930820657, "ENTRESTO": 9.188865675520768, "EXJADE": 3.036101144071559, "FENTANYL": 0.6997322325414588, "FIRDAPSE": 4.827315829800914, "HUMAN": 3.705436990876408, "JANUMET": 1.6075756606688243, "JANUVIA": 1.1870763364979269, "KYMRIAH": 8.987968137474015, "KYPROLIS": 5.086940471619675, "MACITENTAN": 22.36448255179425, "MELPHALAN": 12.324453460790409, "NPLATE": 2.727583185079108, "OPSUMIT": 55.12319817743671, "OPTIMARK": 3.722330189238125, "PLAVIX": 0.6774091858596589, "PRIVIGEN": 5.632508870372009, "REVATIO": 9.17370626259317, "SILDENAFIL": 8.356937713996084, "SOLIRIS": 7.352133293023371, "SPIKEVAX": 0.1634739284896841, "SUTENT": 0.9194978278770696, "TRACLEER": 27.857632952953256, "VAXZEVRIA": 0.0554822358679675, "VELTASSA": 14.59895076502313, "VOTRIENT": 1.500481497599785, "XARELTO": 3.858669192579097, "YESCARTA": 4.527191962245125, "null": 1.0814345372648466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5902.json
index cbdb2fcfe22..fb9a2645059 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5902.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5902.json
@@ -1 +1 @@
-{"CELLCEPT": 1.4462041163861872, "CHAMPIX": 1.0281277523843146, "CICLOSPORIN": 2.5797796343472803, "CIMZIA": 1.3314586040645728, "CLOPIDOGREL": 1.399934318177873, "COSENTYX": 2.12682000959752, "CYTARABINE": 3.194451962349238, "DARUNAVIR": 15.234661281625398, "DEXAMETHASONE": 1.5298071329721743, "ENBREL": 1.5988070528592744, "HYDROCORTISONE": 13.173859414567607, "IBRANCE": 2.2929451276594057, "INCIVO": 2.899656222909162, "INLYTA": 2.5187622762524584, "METHOTREXATE": 1.455997926444409, "NEXAVAR": 1.80999874127508, "NUCALA": 2.769775191093403, "PEGASYS": 1.139701495999751, "PEGINTERFERON": 3.681851384405282, "RITUXIMAB": 1.5591284754673909, "SUTENT": 5.317212899986992, "VFEND": 1.6808425439845818, "ZOSTAVAX": 1.1961294502266044, "null": 1.4705133656533091}
\ No newline at end of file
+{"CABAZITAXEL": 376.3944572979013, "CLOPIDOGREL": 13.356422923926104, "EYLEA": 42.69121250321484, "null": 1.3074743018581303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5903.json
index 66d2ba0d72a..b48254bfee9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5903.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5903.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7760447099983492, "SYCREST": 163.14584172802412, "null": 1.5460719184663778}
\ No newline at end of file
+{"null": 1.570883897646029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5904.json
index 5ef531dc428..44f690208bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5904.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5904.json
@@ -1 +1 @@
-{"BUDESONIDE": 1.9460666567029004, "CIMZIA": 1.6781899545635284, "COSENTYX": 7.325967297772159, "JARDIANCE": 6.742257935427442, "KEYTRUDA": 1.384714443246095, "PEGASYS": 3.160035187627252, "RELVAR": 38.87649016416324, "SIMPONI": 2.3414551151931, "SUTENT": 1.2203817008091131, "TRELEGY": 6.13038502662616, "XELJANZ": 1.3240992472508657, "null": 1.7105470025887803}
\ No newline at end of file
+{"DELAMANID": 726.6622874169204, "null": 0.4546645556637538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5905.json
index 35380bc89c2..e075b540497 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5905.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5905.json
@@ -1 +1 @@
-{"ACLASTA": 11.519342555804696, "AFINITOR": 1.2680462906519494, "ALEMTUZUMAB": 2.250134324863444, "ANAKINRA": 1.554003113795956, "ASPARAGINASE": 11.192740755611666, "AUBAGIO": 1.7328218616905862, "COMIRNATY": 2.390073072406059, "COSENTYX": 3.5874707218909667, "COVID19": 1.837989018704783, "CYTARABINE": 2.2722103677390884, "DEXAMETHASONE": 1.0185162240946295, "FASENRA": 1.3007026438106584, "HUMIRA": 2.809506000810029, "IBRANCE": 1.525139768292748, "JAKAVI": 1.074300243620186, "KESIMPTA": 9.870295650029282, "LEMTRADA": 1.960842900341172, "LUTATHERA": 6.461218656891535, "MAVENCLAD": 18.53042827262662, "METHOTREXATE": 2.1170145290911933, "NAGLAZYME": 1.969900948184911, "OMALIZUMAB": 1.0723159210387516, "PEGASYS": 1.4181507346082407, "PEGINTERFERON": 1.661133705920628, "REMICADE": 1.9172821144094951, "RINVOQ": 10.802274084733094, "ROACTEMRA": 3.2173590882702285, "SHINGRIX": 9.725664672497496, "SIMPONI": 3.464327395712661, "SPIKEVAX": 1.6314271960533475, "STELARA": 1.2009869876057606, "TOZINAMERAN": 1.0778678940581037, "TREMFYA": 1.993531475387952, "TWINRIX": 1.3488973822953547, "UPADACITINIB": 14.211142165000236, "VAXZEVRIA": 1.2212367516425184, "XELJANZ": 2.901829524858127, "ZOSTAVAX": 3.810454711025185}
\ No newline at end of file
+{"ABASAGLAR": 1.459604475496402, "ABILIFY": 0.5907630793923306, "ADCIRCA": 1.9862734573031764, "AFINITOR": 0.207301306397548, "AIMOVIG": 0.3960811729077077, "ALENDRONATE": 41.48833084888079, "ALIMTA": 0.6305282421294672, "AMBRISENTAN": 2.7914124321681166, "AMIKACIN": 5.561955307910981, "AMINOSALICYLIC": 1.8381590022082228, "APIDRA": 1.0803638457140885, "APIXABAN": 3.2317399542383733, "APROVEL": 1.084430136874423, "ARAVA": 0.1767133720537364, "ARIPIPRAZOLE": 0.27994146956161, "AUBAGIO": 0.3456450921967462, "BEDAQUILINE": 5.581467396940961, "BOSULIF": 2.2282561587304284, "BRAFTOVI": 3.512072497298039, "BUDESONIDE": 1.6096334479364356, "BUPIVACAINE": 3.1589771789243724, "BYDUREON": 1.3642779826156957, "BYETTA": 0.44087019135341, "CANAGLIFLOZIN": 27.607263052420763, "CELLCEPT": 0.5164888043715443, "CHAMPIX": 0.3414728257825539, "CICLOSPORIN": 0.1334392954463966, "CLOPIDOGREL": 0.4102834792958806, "COMIRNATY": 0.8904519424307263, "COSENTYX": 0.755683287291493, "CYMBALTA": 0.3871937369246119, "DEXAMETHASONE": 0.4201270413106329, "ELIQUIS": 2.004928236849814, "ENBREL": 0.3439647217887315, "ENTRESTO": 0.5497926597754323, "EPIVIR": 1.6725336533005888, "ESBRIET": 1.2032143094941858, "EXFORGE": 1.842659530533455, "EXJADE": 6.994626796362686, "FAMPYRA": 0.7954449872730829, "FASENRA": 1.2585758165083385, "FASLODEX": 0.7457447239546816, "FORSTEO": 0.553260127408263, "FORXIGA": 0.3843942818682214, "GARDASIL": 1.1931556921898816, "HALAVEN": 2.378341657653164, "HUMALOG": 4.181135791437674, "HUMIRA": 0.4843946232130764, "HYDROCORTISONE": 2.475972254251155, "IBRANCE": 3.867145519346536, "INCIVO": 0.7230169459164786, "INLYTA": 1.3781060178944489, "INSULIN": 0.9247115150350044, "INTRONA": 3.2731994039646195, "JANUMET": 0.7177085366414404, "JANUVIA": 0.6451769059796182, "JARDIANCE": 0.7648380503694424, "KEPPRA": 0.7179170455141789, "KEYTRUDA": 0.1990940533023447, "LANTUS": 3.906283847827712, "LEVEMIR": 1.933824897500116, "LEVOFLOXACIN": 0.6985659138941074, "LYRICA": 1.6702599604388015, "MICARDIS": 1.8654834763844428, "MODERNA": 1.1869036454508175, "NAGLAZYME": 1.4639985543174143, "NEXAVAR": 0.2758304002595028, "NIMENRIX": 0.6255973822333454, "NUCALA": 0.5874723821160105, "OMALIZUMAB": 0.9371120500748008, "OPDIVO": 0.4940749725053121, "OPSUMIT": 1.0388412527576332, "PEGASYS": 1.132140160856937, "PEGINTRON": 3.007403261588615, "PLAVIX": 0.5195024496911689, "RANOLAZINE": 6.34936203738101, "REBETOL": 2.087650728614624, "REVATIO": 5.718603293175185, "ROACTEMRA": 0.5313501586941141, "SHINGRIX": 0.681127639793617, "SILDENAFIL": 2.92578156339221, "SIMPONI": 0.2020405292708064, "SPIKEVAX": 0.7808716410441023, "SPRYCEL": 0.5118429857162757, "STELARA": 0.3046954630889407, "SUBOXONE": 0.2654525029276426, "SUTENT": 0.7309176164693345, "TAMIFLU": 0.6325802129425069, "TASIGNA": 0.3360747892603551, "TELMISARTAN": 1.5931691578156657, "THALIDOMIDE": 1.4208622505564803, "TOBRAMYCIN": 5.693827936897788, "TOUJEO": 3.282747246954409, "TOVIAZ": 4.831763995942214, "TOZINAMERAN": 1.1185519740521073, "TRACLEER": 0.500896461798761, "TRULICITY": 0.9843031056955576, "VAXZEVRIA": 0.4724034764128877, "VELTASSA": 1.128672240019439, "VFEND": 1.2688760610479892, "VIAGRA": 9.314588498317466, "VICTOZA": 0.5301344359086846, "VOTRIENT": 0.3149105024198966, "XALKORI": 1.2554567500600042, "XELJANZ": 4.138221430815063, "XOLAIR": 0.7373709491208348, "XTANDI": 0.9774260259588212, "ZOSTAVAX": 1.5972994491721255, "ZYPREXA": 0.4070631529072576, "null": 1.2361560001646146}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5906.json
index 02e9313c6f2..ee6d925952f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5906.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5906.json
@@ -1 +1 @@
-{"COMIRNATY": 1.8190982598616368}
\ No newline at end of file
+{"ABACAVIR": 0.2042630871319227, "ABASAGLAR": 0.5147100165974071, "ABATACEPT": 1.481378728416206, "ABILIFY": 0.3382602856974643, "ACTOS": 0.3733390341550047, "ADALIMUMAB": 1.811665588772617, "ADCETRIS": 0.6746988392002934, "ADCIRCA": 0.3414387645596372, "ADENURIC": 0.7067761023509734, "AFINITOR": 0.2669867931917837, "AIMOVIG": 2.858227048889497, "ALDARA": 0.620596906930126, "ALEMTUZUMAB": 0.7822731653318803, "ALIMTA": 0.2010517502287898, "AMINOSALICYLIC": 0.2167570047526308, "ANAKINRA": 0.0979908804252616, "APIDRA": 0.394820969030731, "APIXABAN": 0.1766940828942944, "APREMILAST": 3.4200725946268364, "ARANESP": 0.0923261184517632, "ARAVA": 0.6131577176671812, "ARIPIPRAZOLE": 0.0987056844230945, "ASPARAGINASE": 0.1818222772673826, "ATRIPLA": 0.0566053635660045, "AUBAGIO": 4.972322448282471, "AVAMYS": 0.7904375133719688, "AVANDAMET": 0.4023470600615973, "AVANDIA": 0.4307119630382138, "AVASTIN": 0.9388461565394156, "AVONEX": 1.430864345743016, "AZATHIOPRINE": 0.458238873015478, "AZILECT": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5907.json
index 388baa7b09a..4d9316c6d89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5907.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5907.json
@@ -1 +1 @@
-{"BENLYSTA": 7.128244385303307, "CIMZIA": 4.213934720723039, "IBRANCE": 5.228113791390726, "PEGASYS": 3.1820411826383297, "SIMPONI": 7.165432470939846, "STELARA": 3.2720420714586163, "SUTENT": 2.229559121109506, "XELJANZ": 4.855985979106284}
\ No newline at end of file
+{"ABILIFY": 197.14982519653017, "COMIRNATY": 1.1245640770794512, "SPIKEVAX": 0.7286395360613322, "TOZINAMERAN": 3.365006154547727, "VAXZEVRIA": 0.6522359358677268, "null": 0.2570626875530107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5908.json
index 1991a9cdc55..633d80b5d0f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5908.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5908.json
@@ -1 +1 @@
-{"CICLOSPORIN": 4.453144601826418, "COMIRNATY": 1.0746809935049937, "ESOMEPRAZOLE": 56.02847417416725, "PEGASYS": 2.498449708420172, "TOZINAMERAN": 2.448894810026476}
\ No newline at end of file
+{"AFINITOR": 0.2878219519719842, "AIMOVIG": 1.22104690959142, "AUBAGIO": 0.6119179619176099, "BRINTELLIX": 0.5194356028123119, "BYDUREON": 0.5876214003481146, "CELLCEPT": 0.3602374506782407, "CHAMPIX": 0.9008779755735916, "CIMZIA": 0.1475672312114103, "COMIRNATY": 2.082868845482584, "COSENTYX": 0.1976713083924966, "CYMBALTA": 0.3598569051365044, "DELTYBA": 18.55018265650824, "ELIQUIS": 0.1325081923804113, "ENTRESTO": 0.3207420712938812, "EVENITY": 1.300348825692058, "EXFORGE": 0.7164453761924852, "FASENRA": 0.9628085214523822, "FENTANYL": 1.3584432403726112, "FIRDAPSE": 12.427589323305709, "FORSTEO": 0.4678478620413773, "GARDASIL": 0.4966108794948183, "HUMALOG": 0.4105049217482076, "IBRANCE": 0.2540144217814286, "KEPPRA": 0.4055618860337788, "KEYTRUDA": 0.1310670084915166, "LANTUS": 0.6053915457006718, "LEVOFLOXACIN": 0.3986250630125046, "LYRICA": 0.4303262408180404, "NEXAVAR": 0.2101182363503375, "OCRELIZUMAB": 0.9370031037484372, "PEGASYS": 0.1807433655005061, "RITUXIMAB": 0.6108826781743565, "SHINGRIX": 0.4595803234863143, "SIMPONI": 0.341378783029219, "SPIKEVAX": 1.098276370638844, "STELARA": 0.4751622333703991, "SUBOXONE": 0.8711063961779738, "SUTENT": 0.4760356439423502, "SYCREST": 22.59341818626025, "TOVIAZ": 1.3406592024032302, "TOZINAMERAN": 3.2935742452394146, "TRELEGY": 0.7344059127480979, "VAXZEVRIA": 1.186582691372983, "VIMPAT": 1.0440186607377375, "XELJANZ": 0.1777532839225062, "XOLAIR": 1.0598316502970544, "XTANDI": 0.4430872838736738, "ZOSTAVAX": 0.3059988077137992, "null": 1.242695027679598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5909.json
index eace1eeae84..5704b43280f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5909.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5909.json
@@ -1 +1 @@
-{"AP": 1806.993202921764, "CICLOSPORIN": 3.3084285036482166, "DEXAMETHASONE": 4.372826671755049, "FENTANYL": 7.29917373500387, "IBUPROFEN": 3.9831365514475183, "KEYTRUDA": 2.8422271894390527, "LYRICA": 4.395163592624496, "NEXAVAR": 6.173828220541467, "STIVARGA": 5.666083055556985, "null": 3.0101624491095134}
\ No newline at end of file
+{"null": 0.8515841511674774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/591.json
index 49497a2bc16..e9060bdc03e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/591.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/591.json
@@ -1 +1 @@
-{"null": 1.906036144418784}
\ No newline at end of file
+{"COMIRNATY": 0.2401097289647706, "null": 2.2635490297651497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5910.json
index 8a596a1d209..60fea9acc97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5910.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5910.json
@@ -1 +1 @@
-{"null": 1.807890886590464}
\ No newline at end of file
+{"AFINITOR": 1.5177537004896444, "ALIMTA": 3.3909226247658046, "AMIKACIN": 6.738321961176094, "AMINOSALICYLIC": 11.426984510850284, "ASPARAGINASE": 6.487132446655406, "AVASTIN": 3.6032389172083135, "BEDAQUILINE": 5.222747348415804, "BEVACIZUMAB": 3.72984040964318, "BUDESONIDE": 1.5454938734935255, "CABOMETYX": 4.69309199306433, "CAPECITABINE": 3.0690309087075587, "CASPOFUNGIN": 15.573376294223124, "CICLOSPORIN": 6.613911526655144, "CLADRIBINE": 16.897952572894162, "COMIRNATY": 0.0478298874049675, "CYTARABINE": 5.501123724480826, "DELAMANID": 11.386066880600126, "DOCETAXEL": 3.4260906695037123, "ELIQUIS": 0.3792469250201634, "ERBITUX": 12.462634104754642, "FILGRASTIM": 10.094315017292956, "IBUPROFEN": 3.1185802282696566, "INTRONA": 7.149185188044743, "KEYTRUDA": 3.1699979924105604, "LAMIVUDINE": 11.400843057685156, "LENVIMA": 4.647739014787701, "LEVETIRACETAM": 1.2772926939431404, "METHOTREXATE": 1.3013435852309148, "NEXAVAR": 4.714868488078781, "OLANZAPINE": 2.2381667009298627, "ONCASPAR": 22.7291142734394, "OPDIVO": 1.5781044481471196, "PEGASYS": 0.8817986265786336, "PEGINTERFERON": 1.998213553158838, "PEGINTRON": 2.078539569897931, "PLAVIX": 0.7695466822590463, "RITUXIMAB": 4.174394487375136, "SPIKEVAX": 0.0473938624844378, "STIVARGA": 5.612907304162706, "SUTENT": 2.4568667420381054, "VFEND": 1.6655247935751831, "VOTRIENT": 2.4101799509869903, "YESCARTA": 21.912588334117206, "ZYPREXA": 0.9404872839011038, "null": 1.0470134854932098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5911.json
index 5105bfb4ef4..1ca9e650d04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5911.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5911.json
@@ -1 +1 @@
-{"AFINITOR": 1.7338648523588178, "AIMOVIG": 1.3254521288536465, "BENLYSTA": 1.995128773274872, "BUPRENORPHINE": 1.8344353068544048, "CABOMETYX": 2.298622037959301, "CHAMPIX": 1.858714318217618, "COSENTYX": 1.005095250299482, "IBRANCE": 2.5852205198454783, "IBUPROFEN": 1.6554012870210206, "IMATINIB": 8.304051904634319, "INLYTA": 4.531119554012507, "PEGASYS": 3.297024115683356, "ROACTEMRA": 2.638078872489457, "SHINGRIX": 3.5862812780054707, "SUBOXONE": 1.233719042649391, "SUTENT": 8.637353692483547, "TASIGNA": 1.5960088760611386, "VOTRIENT": 1.3208615382969684, "null": 1.580698406323818}
\ No newline at end of file
+{"null": 1.0022048488299071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5912.json
index 8600c7afbdb..7f47674983f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5912.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5912.json
@@ -1 +1 @@
-{"STALEVO": 96.12341708593657, "null": 2.860039857558307}
\ No newline at end of file
+{"null": 1.223833840850454}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5913.json
index 3439d066713..e65c0b24c03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5913.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5913.json
@@ -1 +1 @@
-{"KEYTRUDA": 1.3341109313060016, "MMRVAXPRO": 5.925652820205065, "PANTOPRAZOLE": 7.882798355272097, "SUTENT": 1.974222085635604, "null": 2.829994390230411}
\ No newline at end of file
+{"ABATACEPT": 0.3831235001770539, "ADALIMUMAB": 3.4448457518504365, "AERIUS": 3.0223892372319776, "AFINITOR": 1.52115614118994, "ALIMTA": 2.173852545930351, "AMINOSALICYLIC": 9.439833480371767, "ANAKINRA": 1.5767424895511042, "ARANESP": 1.217765708203759, "ARAVA": 0.0692856262113634, "AVASTIN": 1.442966146338725, "BEDAQUILINE": 5.7005565431640655, "BEVACIZUMAB": 1.9055620897824217, "BONVIVA": 9.375353809534593, "BORTEZOMIB": 3.996073076073188, "BUDESONIDE": 0.4736940537186976, "CABOMETYX": 6.103868519239276, "CAPRELSA": 13.812540258386909, "CELLCEPT": 1.7293979817207463, "CICLOSPORIN": 0.4164889852180451, "CINACALCET": 116.03859378297116, "COMBIVIR": 3.449456698593633, "COMIRNATY": 0.0180097651982559, "DARZALEX": 1.9583293227073768, "DELAMANID": 7.928129374143202, "DENOSUMAB": 14.78450658727745, "DEXAMETHASONE": 2.5912451362546096, "DOCETAXEL": 2.876503960970272, "DULOXETINE": 2.8506255175982385, "ELIQUIS": 0.193891699008634, "ERBITUX": 15.833808627480296, "ESOMEPRAZOLE": 4.315214533170031, "EVENITY": 20.622950207417933, "EXJADE": 0.7016016584118565, "FENTANYL": 1.7620981467725574, "FILGRASTIM": 3.3445146855594885, "FORSTEO": 1.6067589621028535, "HYDROCORTISONE": 1.6754069385334929, "IBRANCE": 0.384513605722947, "IBUPROFEN": 0.7990889265470972, "JANUMET": 0.8496079160953686, "JEVTANA": 3.3145491172610684, "KALETRA": 1.2272035516110609, "KEPPRA": 0.365759325172895, "KEYTRUDA": 1.8425442112347223, "KISQALI": 2.4715232658730213, "LENVIMA": 3.827131628437941, "LEVETIRACETAM": 1.2845358935823366, "LEVOFLOXACIN": 1.618773987612315, "LOXAPINE": 28.709133522073564, "METHOTREXATE": 1.6529725394827242, "MIDAZOLAM": 1.943491076578404, "MIMPARA": 164.03636205488937, "NATPAR": 270.811839485896, "NEXAVAR": 4.161016356003176, "NUCALA": 0.7704468820086564, "OLANZAPINE": 2.199243004406199, "PANTOPRAZOLE": 7.252358808759367, "PEGASYS": 0.4499396811033064, "PEGINTERFERON": 1.2946418703067963, "PEMBROLIZUMAB": 1.8017569185932565, "PROLIA": 44.18413924393011, "REVATIO": 1.9857708746728877, "RIBAVIRIN": 7.493382316681053, "SORAFENIB": 9.6470695970997, "STIVARGA": 3.3513129373358432, "SUTENT": 1.244844952871515, "TRUVADA": 0.1398471974190451, "VAXZEVRIA": 0.0167447322550146, "VECTIBIX": 8.870293595804027, "VILDAGLIPTIN": 20.615279119395343, "VIREAD": 2.323657612204268, "XGEVA": 45.58729986690024, "XTANDI": 0.6054236117582262, "ZOLEDRONIC": 65.58578364951654, "ZOMETA": 19.713913298984803, "ZYPREXA": 0.9239747273622748, "null": 1.6493328976197947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5914.json
index 11d63ee3844..056e5b4282b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5914.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5914.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.906504768857109, "SUTENT": 4.039736141105351, "null": 3.286674079163142}
\ No newline at end of file
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5915.json
index 8bd80e72989..8ae9bcf1a27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5915.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5915.json
@@ -1 +1 @@
-{"SUTENT": 4.491476899651225, "null": 2.6578987005891603}
\ No newline at end of file
+{"null": 5.393553616600018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5916.json
index c6bef3776f9..7081ec751c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5916.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5916.json
@@ -1 +1 @@
-{"null": 2.208597383915884}
\ No newline at end of file
+{"null": 2.1954124053828687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5917.json
index 7b5a4078c35..84ef56e525a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5917.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5917.json
@@ -1 +1 @@
-{"AFINITOR": 5.999807247439297, "ANORO": 2.122968996765015, "APREPITANT": 1.6227202252541524, "ARAVA": 1.1734760392020658, "AVASTIN": 1.076133747353523, "BEVACIZUMAB": 1.9746840020663063, "CABOMETYX": 4.216097954438656, "COSENTYX": 1.712711744269544, "DEXAMETHASONE": 2.0661099463228787, "FASLODEX": 1.1591087701534266, "HERCEPTIN": 1.941191872396056, "IBRANCE": 4.754720436185472, "INCIVO": 2.1455777641952323, "INLYTA": 7.741015213140715, "IRINOTECAN": 1.5684196006042042, "KISQALI": 1.2689481703031895, "LENVIMA": 1.8809146231639504, "NEULASTA": 3.890357200295511, "NEXAVAR": 2.1853232110713425, "OCALIVA": 3.645594118980828, "PEGASYS": 1.8311712553178772, "PEGINTERFERON": 1.167753371332649, "PEGINTRON": 1.2233013985783103, "RELVAR": 9.455345454321089, "STIVARGA": 2.9663636300145666, "SUTENT": 19.97053325621103, "TAGRISSO": 1.2504905544535998, "TORISEL": 3.0025155885227512, "TRELEGY": 2.4985562764383187, "UMECLIDINIUM": 8.410569975546164, "VOTRIENT": 2.1067785853905527, "null": 1.6688241403111157}
\ No newline at end of file
+{"null": 8.003394656024124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5918.json
index 475e8e6ceef..db523c3d236 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5918.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5918.json
@@ -1 +1 @@
-{"null": 4.910307140806525}
\ No newline at end of file
+{"COAPROVEL": 38.10525427275213, "CYMBALTA": 1.591089029060563, "null": 5.014912249182941}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5919.json
index 1c4eecb4ec5..ba711faadef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5919.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5919.json
@@ -1 +1 @@
-{"null": 1.1196148430104418}
\ No newline at end of file
+{"null": 2.6196295054388483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/592.json
index d8c79d04a53..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/592.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/592.json
@@ -1 +1 @@
-{"COVID19": 2.14016194061601, "FORSTEO": 16.79240931345673, "NEULASTA": 69.43368450228891, "null": 1.7492918094459085}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5920.json
index 35647b116fe..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5920.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5920.json
@@ -1 +1 @@
-{"RITUXIMAB": 1.772536036726702, "XOLAIR": 1.6010279491408252, "null": 6.922923128016432}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5921.json
index 8404b2035da..006c17aa79a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5921.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5921.json
@@ -1 +1 @@
-{"null": 1.5183052269791055}
\ No newline at end of file
+{"ENTRESTO": 110.26949182621678, "null": 0.4019967776605336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5922.json
index fbe18be14dd..8a78dfd1173 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5922.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5922.json
@@ -1 +1 @@
-{"ENBREL": 13.751976031298096, "IBRANCE": 10.91489074330277, "XELJANZ": 6.936227928532146, "null": 1.0284719844397054}
\ No newline at end of file
+{"COMIRNATY": 0.1215751324474063, "IBUPROFEN": 7.818708061437475, "PLAVIX": 4.37444874164376, "null": 1.6908207108875115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5923.json
index 9f3523001b9..36a2f34e9c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5923.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5923.json
@@ -1 +1 @@
-{"null": 2.567861733067455}
\ No newline at end of file
+{"null": 4.799161565403609}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5924.json
index de550285bad..a3d9564b14b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5924.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5924.json
@@ -1 +1 @@
-{"IPILIMUMAB": 162.43734978402895}
\ No newline at end of file
+{"CLOPIDOGREL": 1.7638082480162665, "LEVOFLOXACIN": 7.722997026076803, "PLAVIX": 1.242022764916893, "null": 14.635225081112107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5925.json
index 180d63623fe..8d9ae55c9d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5925.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5925.json
@@ -1 +1 @@
-{"SUTENT": 4.659195817524316, "null": 2.7476276713017143}
\ No newline at end of file
+{"null": 1.9510687911938975}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5926.json
index 90b66eda774..9f8b96f1cd4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5926.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5926.json
@@ -1 +1 @@
-{"JARDIANCE": 42.51197865267931}
\ No newline at end of file
+{"ASPARAGINASE": 23.917903852160908, "DEXAMETHASONE": 6.539176030283298, "KYMRIAH": 57.89219235225119, "ONCASPAR": 136.5486105268739, "ROACTEMRA": 84.08266965052248, "TOCILIZUMAB": 615.9541135263365, "VAXZEVRIA": 0.3967172303591179, "null": 0.4430214823284705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5927.json
index 61f234bf159..8da9829e533 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5927.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5927.json
@@ -1 +1 @@
-{"FORXIGA": 25.09707029000772, "JARDIANCE": 19.368833094296768, "KAFTRIO": 32.56816283301198, "MMRVAXPRO": 9.51702650626466}
\ No newline at end of file
+{"ALEMTUZUMAB": 13.583497524895552, "AMIKACIN": 13.352707042156537, "ARAVA": 0.4146514599305153, "AUBAGIO": 2.186210884117386, "AXICABTAGENE": 81.93672085599854, "BORTEZOMIB": 24.2398337978363, "BUDESONIDE": 5.498851029827721, "CARFILZOMIB": 19.8432950123894, "CELLCEPT": 9.908651062245813, "CICLOSPORIN": 6.789020126145987, "COMIRNATY": 0.0868137507853087, "CYTARABINE": 29.900991162195343, "DARZALEX": 18.189020058063782, "DEXAMETHASONE": 9.873258978983696, "DOXORUBICIN": 7.427778595904688, "FILGRASTIM": 18.21006282910948, "GLYCOPYRRONIUM": 34.792259578287414, "JAKAVI": 3.3697185912527936, "KEPPRA": 1.4179189960858627, "KYMRIAH": 140.2758781423761, "MABTHERA": 15.9027082667804, "METHOTREXATE": 5.215096236266903, "MYCOPHENOLATE": 7.769776719502889, "OBINUTUZUMAB": 55.98488618870621, "RITUXIMAB": 26.42512546433008, "YESCARTA": 78.53503916656763, "null": 0.3975970676284043}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5928.json
index 15574012c4f..c669f47c405 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5928.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5928.json
@@ -1 +1 @@
-{"null": 4.406448101978552}
\ No newline at end of file
+{"CHAMPIX": 1.666255910469532, "COMIRNATY": 1.5008608796350384, "SPIKEVAX": 1.092207475862219, "SUTENT": 11.05138683276546, "TOZINAMERAN": 0.315168965069298, "VAXZEVRIA": 0.8239114362987607, "XTANDI": 2.106872608271572, "null": 1.1621815751461766}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5929.json
index 1811d144c70..febbec2d336 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5929.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5929.json
@@ -1 +1 @@
-{"BUSULFAN": 10.21027844138946, "CANCIDAS": 40.14281119641697, "DEXAMETHASONE": 3.03616761981253, "ELIQUIS": 1.413527851123045, "HUMALOG": 1.964108682803814, "REVATIO": 8.35955780544161, "SUTENT": 8.207455905864984}
\ No newline at end of file
+{"ABASAGLAR": 27.470713776110543, "ABILIFY": 0.365427351410536, "ACOMPLIA": 7.467673101849119, "ACTOS": 19.157579612427885, "ACTRAPHANE": 55.75845621501416, "ACTRAPID": 48.13772001110835, "AFINITOR": 0.2884302981748465, "AIMOVIG": 0.0376707861764588, "ALISKIREN": 0.5232428236421892, "AMIKACIN": 0.3640488219112857, "AMINOSALICYLIC": 0.4075722584536106, "APIDRA": 42.348444129641486, "APIXABAN": 0.0510968369642436, "APROVEL": 0.585814657412829, "ARANESP": 0.1549214692293483, "ARAVA": 0.0283797862885033, "ARIPIPRAZOLE": 0.1023074092390401, "ASPARAGINASE": 0.309328456183283, "ATAZANAVIR": 0.1411163127929781, "AVANDAMET": 0.9846070166599274, "AVANDIA": 1.5119721734712668, "AVASTIN": 0.1358218117013567, "AXITINIB": 0.6834367000685517, "BAQSIMI": 45.51532470215711, "BEDAQUILINE": 0.5215491233128982, "BUDESONIDE": 0.0459034315478335, "BUMETANIDE": 0.7225814096337615, "BUPRENORPHINE": 0.3641371672564383, "BYDUREON": 0.976647472404966, "BYETTA": 2.445335534522721, "CABOMETYX": 0.1496347984871902, "CANAGLIFLOZIN": 9.871205438828682, "CANCIDAS": 0.3195189986092008, "CAPECITABINE": 0.2809874257704249, "CELECOXIB": 0.2371081457615573, "CELLCEPT": 0.0644871729280765, "CHAMPIX": 0.2374295385353616, "CICLOSPORIN": 0.1327010251125891, "CIMZIA": 0.0316472785454359, "CLOPIDOGREL": 0.5905697868479696, "COAPROVEL": 0.2138254632007584, "COMBIVIR": 0.2567726178471091, "COMIRNATY": 0.0412956787200012, "COMPETACT": 52.72764181620155, "COMTAN": 0.4049025897982847, "CORTICOSTEROID": 4.246334857826197, "CORTICOSTEROIDS": 1.9156777697804133, "COSENTYX": 0.0939855014166996, "COTELLIC": 0.2923713868554804, "CUBICIN": 0.1906840986286994, "CYMBALTA": 0.1953638753532076, "CYTARABINE": 0.0570622479215674, "DAPAGLIFLOZIN": 10.9954473661268, "DELAMANID": 0.6884567190497474, "DENOSUMAB": 1.3814379853175478, "DEVICE": 21.92432809857477, "DEXAMETHASONE": 0.1929316283421296, "DOCETAXEL": 0.1072595898096187, "DRUG": 6.387033899506927, "DULAGLUTIDE": 6.798811512884453, "DULOXETINE": 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"INLYTA": 0.288334862388838, "INSULATARD": 35.31091219850383, "INSULIN": 38.38230946323628, "INSUMAN": 28.73829489155645, "INVIRASE": 1.0222436721038983, "INVOKANA": 2.603200402320889, "IRBESARTAN": 0.4643144968257237, "IRESSA": 0.1410879362209701, "ISOPHANE": 19.69359836574509, "JANUMET": 3.8262306516846607, "JANUVIA": 7.818565274785982, "JARDIANCE": 2.4300446539057488, "KAFTRIO": 0.528840508368032, "KALETRA": 0.121138389943258, "KEPPRA": 0.2180750084445996, "KEYTRUDA": 0.1579262788999644, "LANTUS": 35.503161697491976, "LATUDA": 0.2205312906140402, "LEVEMIR": 23.530696203986917, "LEVETIRACETAM": 0.3667550761130881, "LEVOFLOXACIN": 1.375799316931767, "LINAGLIPTIN": 14.509649698233726, "LIPROLOG": 10.240312160809149, "LIRAGLUTIDE": 4.728896285801191, "LYRICA": 0.2909269316376561, "LYUMJEV": 14.840485089462495, "MEPOLIZUMAB": 0.1272495650951654, "MERCAPTOPURINE": 1.1378568791124155, "METFORMIN": 5.966119298595938, "MICARDIS": 2.067289156562403, "MIDAZOLAM": 0.1547893128745574, "MIRCERA": 0.3330585703533666, "MIXTARD": 34.552746984138324, "MOUNJARO": 10.87149494834562, "MYCOPHENOLATE": 0.1809826757282488, "NEVIRAPINE": 0.8289835114652426, "NEXAVAR": 0.3882071591580475, "NOT": 0.4090637336416117, "NOVOMIX": 35.05648956645474, "NOVONORM": 71.2036395853591, "NOVORAPID": 35.69097452180055, "OLANZAPINE": 0.5211078459602589, "ONGLYZA": 2.1382084243749944, "OPDIVO": 0.2310808528602102, "OPSUMIT": 0.0623549916527512, "OPTIMARK": 0.0719756516618183, "ORKAMBI": 0.3573009662786764, "OZEMPIC": 2.4382117764287923, "PANTOPRAZOLE": 0.2357340269545073, "PEGASYS": 0.0979022938583241, "PEGINTERFERON": 0.1368312145038874, "PEGINTRON": 0.1805497937317351, "PIOGLITAZONE": 16.12343243709669, "PLAVIX": 0.1862696632281786, "PRANDIN": 13.255689746409368, "PROPRANOLOL": 1.8311552377690128, "PROTAPHANE": 39.81576644763496, "RANEXA": 0.5471047887188171, "REPAGLINIDE": 71.80241591451644, "RISPERIDONE": 0.636304422890097, "ROACTEMRA": 0.1065563923312374, "RYBELSUS": 1.055002554599371, "SAXAGLIPTIN": 13.6410932370172, "SAXENDA": 1.337981266376726, "SEMAGLUTIDE": 2.080442388671336, "SILDENAFIL": 1.0001901604078167, "SIMPONI": 0.0405217010300811, "SITAGLIPTIN": 13.789757839468932, "SOMATROPIN": 2.576591646842401, "SPIKEVAX": 0.023305856436052, "SPINRAZA": 0.4145588688337079, "SPIRONOLACTONE": 0.7939523013198917, "STELARA": 0.0761559274239641, "STIVARGA": 0.1609038345805112, "SUTENT": 0.2120941826626304, "TAMIFLU": 0.2291200493421626, "TELMISARTAN": 0.4047862803955646, "TOUJEO": 16.311526051220454, "TOZINAMERAN": 0.0610686804130812, "TRACLEER": 0.214786613992497, "TRAJENTA": 32.59188134541195, "TRESIBA": 44.7046347125016, "TRULICITY": 2.7279848811329166, "TRUVADA": 0.0126148630722163, "VAXZEVRIA": 0.0292431330517971, "VELMETIA": 1.6964304903849092, "VELTASSA": 0.2563297940950345, "VFEND": 1.325579986368613, "VICTOZA": 2.625639252258717, "VILDAGLIPTIN": 11.471448202273892, "VIMPAT": 0.186894893388789, "VORICONAZOLE": 0.7560256839094095, "VOTRIENT": 0.1716488118809375, "XELEVIA": 12.429759756931611, "XELJANZ": 0.0312407288399858, "XOLAIR": 0.1026821031555606, "XTANDI": 0.0693596113748802, "ZOSTAVAX": 0.0481996846247048, "ZYPREXA": 1.0429118502824528, "null": 0.9342737807891288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/593.json
index 8775f9dd7c3..f4103b7f4c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/593.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/593.json
@@ -1 +1 @@
-{"ALDARA": 59.00338709100504, "BUPRENORPHINE": 5.458120222090591, "EVRA": 20.209520669171948, "QUTENZA": 451.2862945158739, "null": 11.906851381874386}
\ No newline at end of file
+{"null": 0.5715551162716871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5930.json
index 96d6ef5aa2f..cc609878268 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5930.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5930.json
@@ -1 +1 @@
-{"ZOSTAVAX": 19.441982514860808, "null": 3.661767206368689}
\ No newline at end of file
+{"ABILIFY": 7.041810677914607, "APIDRA": 6.384039351429727, "COAPROVEL": 18.32798518997678, "HUMALOG": 7.40201189227814, "INSULATARD": 81.07501212520336, "INSULIN": 51.724212301366855, "KEPPRA": 2.9716734521825767, "LANTUS": 10.928390424758552, "LEVEMIR": 34.729448446951025, "LEVETIRACETAM": 4.509074734901488, "NOVORAPID": 13.317876542258707, "SUBOXONE": 7.794184723736071, "null": 1.5629576391173532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5931.json
index 3875f0b48fa..62401f0e1f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5931.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5931.json
@@ -1 +1 @@
-{"AFINITOR": 2.239683745433949, "ALEMTUZUMAB": 4.291803685718118, "ALIMTA": 6.0488465658707575, "BUSULFAN": 2.603624781525339, "CELLCEPT": 1.8655743162260343, "CICLOSPORIN": 3.223942193906272, "CIMZIA": 1.3076744886121086, "CUBICIN": 23.709829370286045, "CYTARABINE": 2.5397925576383256, "ENTYVIO": 3.442931792742111, "FASENRA": 4.02091734505425, "HUMIRA": 1.9768369258791345, "IPILIMUMAB": 3.560433136185261, "JAKAVI": 1.9993613320706984, "KALETRA": 3.4972754920815365, "KEYTRUDA": 15.58186271957175, "METHOTREXATE": 3.813203767555988, "OPDIVO": 12.062849410281848, "PEGASYS": 1.2690652321366898, "PEGINTERFERON": 3.297238594525865, "PEGINTRON": 1.4839240871060764, "PEMBROLIZUMAB": 12.523307405207756, "RAPAMUNE": 16.689030056545406, "RINVOQ": 2.4237319910097623, "ROACTEMRA": 3.0779881733699046, "SIMPONI": 3.6307687913081903, "STELARA": 1.7724435051479843, "TOCILIZUMAB": 15.887612891414657, "null": 1.1234402232680551}
\ No newline at end of file
+{"APIDRA": 12.247699725669852, "HUMALOG": 81.6082116097719, "INSULIN": 36.922423731495655, "LANTUS": 23.61632044948392, "LEVEMIR": 35.38262414628692, "NOVORAPID": 61.90930039064607, "TRESIBA": 55.27004942570008, "null": 0.3608193884260709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5932.json
index b48f3315a4f..7f97f99bf23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5932.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5932.json
@@ -1 +1 @@
-{"BRINTELLIX": 43.18643723930584, "CYMBALTA": 5.169963519201124, "VIAGRA": 15.048400772538647, "null": 4.273314163819546}
\ No newline at end of file
+{"ABASAGLAR": 9.719689281518743, "ACTOS": 12.831146775899136, "ACTRAPHANE": 170.29349442168697, "ACTRAPID": 64.03942587244862, "APIDRA": 26.74778142625806, "AVANDIA": 0.5073987761398135, "BUPRENORPHINE": 3.256506660540679, "BYDUREON": 0.7373882368404953, "DAPAGLIFLOZIN": 45.818997838559646, "FORXIGA": 2.2602542265372394, "GALVUS": 2.7056240675604366, "GLIBENCLAMIDE": 39.63162497496122, "GLUCAGON": 11.010667654901065, "HUMALOG": 26.64688933407961, "INSULATARD": 34.002637622298, "INSULIN": 41.78245654915433, "INSUMAN": 35.20144740261754, "JANUMET": 2.0890449551097547, "JANUVIA": 7.876784529663348, "JARDIANCE": 0.4785160899197651, "LANTUS": 32.33117007941675, "LEVEMIR": 28.79667530632921, "LEVOFLOXACIN": 0.5044409255300732, "MIXTARD": 117.8720885637614, "NOVOMIX": 165.189958337253, "NOVONORM": 124.80168898165324, "NOVORAPID": 40.722653022288696, "ONGLYZA": 4.400593851614851, "PIOGLITAZONE": 27.96394571728185, "PRANDIN": 104.73430579604802, "PROTAPHANE": 52.756719255320775, "REPAGLINIDE": 74.39386919495901, "TOUJEO": 2.698932040269262, "TRESIBA": 28.57195786486116, "TRULICITY": 0.6680330888048013, "VILDAGLIPTIN": 17.5055450558708, "null": 1.1241966812327102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5933.json
index be14faa7a52..1d9f36cad54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5933.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5933.json
@@ -1 +1 @@
-{"null": 6.024203529332313}
\ No newline at end of file
+{"APIDRA": 26.807699731151043, "FORXIGA": 11.4753498725451, "GLIBENCLAMIDE": 109.90323462233904, "HUMALOG": 9.389216812638152, "INSULIN": 39.824326529782674, "JANUVIA": 18.55567434269789, "LANTUS": 12.699282658650931, "LEVEMIR": 20.249479313150744, "NOVORAPID": 35.470725986630804, "TRESIBA": 55.51729358738868, "null": 1.192863038250526}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5934.json
index 0e0ce7f917c..cabfaf3b29d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5934.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5934.json
@@ -1 +1 @@
-{"ENTACAPONE": 258.7186522340258, "LATUDA": 41.06326569656673, "LEVODOPA": 128.2575176357359, "OLANZAPINE": 13.729124271715389, "null": 2.2883546138442954}
\ No newline at end of file
+{"ACTRAPID": 29.959368756581004, "APIDRA": 30.737591958111693, "GLUCAGON": 34.40708570720253, "HEMANGIOL": 309.97633300646106, "HUMALOG": 38.83252482378238, "INSULIN": 20.13314877417417, "LANTUS": 76.27029598531811, "LEVEMIR": 42.52058456143703, "NOVONORM": 45.6029861522495, "NOVORAPID": 30.32009886417246, "TRESIBA": 32.32918555067968, "null": 0.45401329176661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5935.json
index 37815fe863a..5204ff842a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5935.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5935.json
@@ -1 +1 @@
-{"SUTENT": 1.7611090155532327, "TOZINAMERAN": 2.387967351399433, "null": 1.3149935286464598}
\ No newline at end of file
+{"ACTRAPID": 29.317153712174655, "APIDRA": 36.21431823849119, "BAQSIMI": 180.40315723235517, "BYETTA": 3.6482375602523343, "FIASP": 20.90015912959503, "GLUCAGON": 29.10304710028644, "HUMALOG": 38.737169970777565, "INSULATARD": 40.13525184457348, "INSULIN": 30.208265493121797, "JANUVIA": 0.9189198453063524, "LANTUS": 70.97612271210569, "LEVEMIR": 66.2890344516306, "NOVONORM": 11.314966706868717, "NOVORAPID": 49.91745438889177, "SAXENDA": 3.59117805970665, "TOUJEO": 4.741306184073823, "TRESIBA": 78.90169064170057, "TRULICITY": 1.173186825204085, "VICTOZA": 4.285234116336723, "null": 0.4248624892816144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5936.json
index d50b73eb212..13c8fb537af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5936.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5936.json
@@ -1 +1 @@
-{"ACLIDINIUM": 342.6936893694759, "ATAZANAVIR": 26.000716492086333, "BUDESONIDE": 4.836272419919271, "COSENTYX": 9.963380005889906, "TRELEGY": 28.255059502047967, "null": 1.349536270916012}
\ No newline at end of file
+{"CYTARABINE": 7.301649011767729, "ZYPREXA": 3.4909112197528485, "null": 3.9458205090471865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5937.json
index d35aa80a0a0..93562c38a3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5937.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5937.json
@@ -1 +1 @@
-{"ABILIFY": 7.23488701428434, "ACLIDINIUM": 22.966397516323312, "APREPITANT": 10.805707007532696, "AVAMYS": 1.3436048920448005, "COMIRNATY": 2.779290323216589, "DARZALEX": 2.3353420716768527, "EXFORGE": 1.137853006597495, "FASENRA": 2.621140735800155, "FASLODEX": 1.3474325111585848, "NUCALA": 1.1553754238553091, "OMALIZUMAB": 1.5790557243861558, "PANTOPRAZOLE": 3.135450896599251, "RELVAR": 10.203478245219232, "RIXATHON": 14.92179927166421, "TOZINAMERAN": 1.633744587023878, "TRELEGY": 3.768375908403298, "null": 1.2851964991778817}
\ No newline at end of file
+{"ZOSTAVAX": 16.992716460965752, "null": 2.981769345817651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5938.json
index ed1acbdaaae..0d48e0ef99f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5938.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5938.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3639552842098417, "null": 1.3383128797207735}
\ No newline at end of file
+{"COMIRNATY": 0.1539227239417992, "null": 4.170314300875232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5939.json
index a385ddcb3d9..054f02e5fbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5939.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5939.json
@@ -1 +1 @@
-{"1": 23.775160354588635, "ACLASTA": 1.997323725006334, "AERIUS": 1.1725252840490803, "ALDARA": 1.470653674141762, "ALEMTUZUMAB": 1.2762201198680594, "ANORO": 1.1907495075990808, "APIXABAN": 2.1477382345962184, "BENLYSTA": 2.5446083217043527, "CASPOFUNGIN": 1.6144825484074856, "COMIRNATY": 1.8571986644051297, "COMPRESSION": 20.3108929873496, "COSENTYX": 2.3821924009514395, "COVID19": 2.3067672486762474, "DARATUMUMAB": 3.2074090862458693, "DUORESP": 6.5982924514366985, "ENTYVIO": 1.5082652881135727, "FASENRA": 1.921785126357816, "FLUCELVAX": 3.9931596685026944, "GARDASIL": 1.640826539525707, "IBRANCE": 1.034840428836866, "INCRUSE": 1.505903117435197, "INFLECTRA": 3.66686313794112, "INLYTA": 1.219105615660079, "KAFTRIO": 1.2558539978278729, "KESIMPTA": 3.124306366718031, "LEMTRADA": 1.3036196879111173, "MEPOLIZUMAB": 2.3394195407731893, "MMRVAXPRO": 1.2603483240191644, "NAGLAZYME": 4.090064569810644, "NEULASTA": 1.0147663263369011, "NIMENRIX": 2.3842329799295467, "NUCALA": 1.3384291398839336, "OCRELIZUMAB": 3.157104655656428, "OMALIZUMAB": 2.697550249608793, "ORENCIA": 1.8361168483806696, "OXYBUTYNIN": 1.4728429938048524, "PASIREOTIDE": 8.802529081531612, "PEGASYS": 1.135694756399706, "RELVAR": 5.264133473007273, "REMSIMA": 3.1328507814803235, "RINVOQ": 1.1959370724874392, "RIXATHON": 1.3898967097111137, "SIMPONI": 1.6667485315692716, "SPIKEVAX": 1.3481416413957803, "THIOTEPA": 1.1896486516383749, "TOVIAZ": 1.2761732337830654, "TOZINAMERAN": 3.360691560852413, "TRELEGY": 1.650802105958704, "TRIUMEQ": 1.0858096071649703, "TWINRIX": 2.029017595718256, "UMECLIDINIUM": 2.1055093908729736, "VAXZEVRIA": 1.186135864064211, "XELJANZ": 1.899303927046897, "XOLAIR": 2.134960302884575, "ZIAGEN": 1.8141083574654315, "ZYCLARA": 2.079486191570606}
\ No newline at end of file
+{"ABACAVIR": 0.2526691276581745, "ABATACEPT": 0.1675009992714575, "ABILIFY": 0.5461322217204054, "ABIRATERONE": 9.00798235062046, "ABRAXANE": 1.0979380799069636, "ACTOS": 0.674610974177481, "ADALIMUMAB": 0.6529852563392577, "ADCIRCA": 1.1842887253035237, "AERIUS": 1.4250936897493651, "AFINITOR": 0.8333798247097381, "ALIMTA": 1.0147733382505175, "ALISKIREN": 1.187285525600404, "ALOXI": 4.068647694150727, "AMIKACIN": 0.8418119486083244, "AMINOSALICYLIC": 4.100992357832779, "ANAKINRA": 0.2751992695301183, "ANTIBIOTICS": 2.498696863856688, "APIXABAN": 0.3482364126980956, "APROVEL": 1.159135355793628, "ARANESP": 0.1504131548144479, "ARAVA": 0.0682660205763296, "ARIPIPRAZOLE": 0.2024150722644321, "ASPARAGINASE": 0.3439709272572765, "ATAZANAVIR": 0.5886022872366039, "ATEZOLIZUMAB": 5.310299828312972, "ATRIPLA": 0.1534564158280536, "AUBAGIO": 0.2265096508167685, "AVASTIN": 0.9219976601693411, "AVELUMAB": 2.020972390119396, "AZACITIDINE": 1.0920705792427443, "BARACLUDE": 0.864094998859118, 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0.8914796033588198, "DARZALEX": 0.614156514003761, "DASATINIB": 0.8800030140484396, "DELAMANID": 7.562096794244004, "DESLORATADINE": 1.2115747719126957, "DEXAMETHASONE": 0.8674599411440973, "DOCETAXEL": 1.311705663835647, "DOXORUBICIN": 0.6792840393540872, "DULOXETINE": 0.8958807949565604, "EFAVIRENZ": 1.0472779420658629, "ELIQUIS": 0.4454092766781279, "EMEND": 1.309127653832956, "EMTRICITABINE": 0.739430126818635, "ENBREL": 0.1364452527785875, "ENOXAPARIN": 0.6223351804780047, "ENTRESTO": 0.8082582425048069, "ENZALUTAMIDE": 1.816250156237935, "ERBITUX": 2.252483852069027, "ERLEADA": 0.5066445244484419, "ESOMEPRAZOLE": 1.402308061362176, "EVENITY": 0.5728313450160076, "EXFORGE": 1.5076125189327831, "EXJADE": 0.8628405883838607, "FASLODEX": 0.2246789818558397, "FENTANYL": 0.6968539757092037, "FILGRASTIM": 2.629480043611476, "FIRDAPSE": 0.9741598507489388, "FORSTEO": 0.2637222018857481, "FORXIGA": 0.382845217728808, "FULVESTRANT": 0.3268154410873058, "GANCICLOVIR": 1.4940753490773382, 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"SUTENT": 0.1320932245538499, "TACROLIMUS": 0.6799585270405931, "TAMIFLU": 0.2315138163489965, "TASIGNA": 0.459200181220696, "TELMISARTAN": 2.273463676710508, "TEMODAL": 0.9575821579872372, "TENOFOVIR": 4.552127168458829, "TOPOTECAN": 1.2099566087477844, "TOVIAZ": 0.2485474713831463, "TOZINAMERAN": 0.0247042423871727, "TRACLEER": 0.4430696710423004, "TRELEGY": 0.2305249413521271, "TRODELVY": 0.9094230497158076, "TRULICITY": 0.2896044061400812, "TRUVADA": 0.3302704466791641, "VALSARTAN": 0.6643519677361096, "VAXZEVRIA": 0.0126893141330487, "VECTIBIX": 1.3972481598511708, "VELCADE": 1.932228816969534, "VELTASSA": 0.8799754203182613, "VFEND": 2.1022499276429425, "VICTOZA": 0.3650159721987671, "VIMPAT": 0.8278306099839975, "VIREAD": 1.0833969542394868, "VORICONAZOLE": 2.495424746309905, "VOTRIENT": 0.207975892480425, "XARELTO": 0.9175970230853896, "XELJANZ": 0.0454062563705435, "XELODA": 1.2102592297143937, "XTANDI": 0.3286222145898096, "ZOMETA": 2.356209244741283, "ZOSTAVAX": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/594.json
index c95c104eb70..ac5be35cc8f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/594.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/594.json
@@ -1 +1 @@
-{"null": 8.637843294500454}
\ No newline at end of file
+{"ASPARAGINASE": 241.2498489251392, "null": 0.4443289456186156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5940.json
index 48eb038504e..6b335483b73 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5940.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5940.json
@@ -1 +1 @@
-{"SUTENT": 3.277288597469136, "null": 1.6311393906523008}
\ No newline at end of file
+{"null": 1.7589940062340212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5941.json
index 7b9a914e041..4447f320360 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5941.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5941.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"ABILIFY": 0.5943829614184297, "ACLASTA": 11.31175437897931, "AFINITOR": 0.4234990827243944, "APIXABAN": 0.6694893867314207, "ARAVA": 0.0502456693037727, "ARIPIPRAZOLE": 0.8596072139045695, "ATRIPLA": 0.2518968688703533, "AUBAGIO": 1.4746710076822551, "AZATHIOPRINE": 0.8342516783510883, "BENLYSTA": 0.868419163367342, "BUMETANIDE": 5.565785141340589, "BYDUREON": 1.082579507333045, "CHAMPIX": 0.3774363502100001, "CICLOSPORIN": 0.548376744936612, "CLOPIDOGREL": 0.7154213971665754, "COMIRNATY": 1.0463219078260548, "COMTAN": 4.05035611719886, "COMTESS": 43.0847079988824, "COSENTYX": 1.218303107787581, "CYMBALTA": 4.018658724545637, "DASATINIB": 6.810363740036559, "DULOXETINE": 6.303645766739907, "ELIQUIS": 0.2619992163983884, "ENOXAPARIN": 1.5378402289269677, "ENTACAPONE": 12.360679957870936, "ENTRESTO": 3.0643111319493146, "EXFORGE": 1.569265262700844, "FENTANYL": 0.7841648136348924, "FORSTEO": 1.7412297093501543, "GARDASIL": 1.1675782536100208, "HUMALOG": 0.8597544051276426, "IBRANCE": 0.8999275350889537, "IBUPROFEN": 1.0797996268539087, "IRBESARTAN": 8.09776737822522, "KEPPRA": 1.0469485280471926, "KEYTRUDA": 0.2898754894364395, "LANTUS": 1.0938283506302793, "LEVETIRACETAM": 0.664767747892384, "LEVODOPA": 5.186140096993126, "LEVOFLOXACIN": 0.5718705838618874, "LYRICA": 1.647978845201342, "MIDAZOLAM": 1.2595620679865358, "NAGLAZYME": 2.110000820419972, "OLANZAPINE": 1.5923736556522208, "OPSUMIT": 0.36828610542217, "PANTOPRAZOLE": 1.7118785006794333, "PEGASYS": 0.203372826381173, "SHINGRIX": 0.8449651360918641, "SIMPONI": 1.502315461698548, "SPIKEVAX": 0.9557731639268702, "STALEVO": 10.896466820444084, "STELARA": 0.357407243777227, "SUBOXONE": 0.4332283058823219, "SUTENT": 0.9351255000361118, "TASIGNA": 0.6136033070398712, "TOUJEO": 1.8192295609003557, "TOZINAMERAN": 2.469675896943856, "TRUVADA": 0.1014166492283728, "TWINRIX": 2.02786042749427, "VAXZEVRIA": 0.6625112591420788, "XELJANZ": 2.070160862577704, "XOLAIR": 1.255566091284958, "XTANDI": 0.9344467191354412, "ZOSTAVAX": 0.2955644812954022, "ZYPREXA": 1.6382671411959502, "null": 1.1546200446342063}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5942.json
index 3d74cba8c2a..af09adb1db6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5942.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5942.json
@@ -1 +1 @@
-{"null": 1.7479467479119173}
\ No newline at end of file
+{"null": 5.195249144307421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5943.json
index ac837444e1b..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5943.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5943.json
@@ -1 +1 @@
-{"XOLAIR": 5.334275528398657, "null": 2.781564216239956}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5944.json
index 3c80da32314..98e53afe0fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5944.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5944.json
@@ -1 +1 @@
-{"null": 2.516331049844454}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5945.json
index 8a421eb1d4c..c0730a23327 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5945.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5945.json
@@ -1 +1 @@
-{"null": 1.1241322145466943}
\ No newline at end of file
+{"ABILIFY": 3.695679976185136, "ACLIDINIUM": 115.1590019708789, "ANORO": 6.455445180043111, "APTIVUS": 58.1016134272866, "ARIPIPRAZOLE": 16.667932204984595, "BREXPIPRAZOLE": 238.816437624049, "BRINTELLIX": 13.208859086668689, "CHAMPIX": 5.579466313599434, "COMTAN": 13.836712275631216, "CYMBALTA": 58.89903311115423, "ENTACAPONE": 18.694912954293475, "KEPPRA": 2.6990587390999234, "LATUDA": 8.795684790603806, "LEVODOPA": 19.62073852543799, "OLANZAPINE": 7.622341997319465, "ZYPREXA": 4.824270892076987, "null": 1.4714003137040272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5946.json
index 16eb7b77a02..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5946.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5946.json
@@ -1 +1 @@
-{"AFINITOR": 2.8104044762110227, "APIXABAN": 4.7469339140936135, "AVANDIA": 11.616204282460613, "BRILIQUE": 8.999511539246154, "BUDESONIDE": 1.1562332641782094, "CLOPIDOGREL": 5.545925999150536, "ENTRESTO": 22.99954149103805, "EXJADE": 2.42879212732862, "MIDAZOLAM": 5.3724385515650965, "NUCALA": 2.153137628093142, "OPSUMIT": 6.6902349670391885, "PLAVIX": 1.48265689540976, "TRACLEER": 8.420093556048611, "VALSARTAN": 11.50886381992278, "VOTRIENT": 3.537026681557241, "null": 1.2914445363208484}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5947.json
index 53032275278..a8649580c85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5947.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5947.json
@@ -1 +1 @@
-{"null": 4.497846157096005}
\ No newline at end of file
+{"COMIRNATY": 9.570765054852728, "ELLAONE": 59.68453358266352, "MODERNA": 1.497516635097717, "SPIKEVAX": 2.143189856438795, "STELARA": 0.3643254591241034, "TOZINAMERAN": 3.2951862130804512, "VAXZEVRIA": 1.2396220236532034, "null": 0.0812786999599348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5948.json
index 85e0ec50796..36ffe1c1556 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5948.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5948.json
@@ -1 +1 @@
-{"ABILIFY": 111.36976972814588, "ARIPIPRAZOLE": 19.919707695499664}
\ No newline at end of file
+{"COMIRNATY": 0.5541403165039407, "null": 1.334769063428159}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5949.json
index 5dd06a45cbe..7024cf5e286 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5949.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5949.json
@@ -1 +1 @@
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\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/595.json
index c1e31260288..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/595.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/595.json
@@ -1 +1 @@
-{"ALDARA": 532.9627777471007, "null": 3.2487421000399466}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5950.json
index 11f63141282..679dd7d41ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5950.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5950.json
@@ -1 +1 @@
-{"COMIRNATY": 1.447570720991174, "GARDASIL": 108.22267915678968}
\ No newline at end of file
+{"null": 8.055428891752898}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5951.json
index 4ebeafd5f84..1aa31cd4fe8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5951.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5951.json
@@ -1 +1 @@
-{"null": 1.3748907022751364}
\ No newline at end of file
+{"SOMATROPIN": 386.1438015596223, "null": 5.10481892239974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5952.json
index 0d6b33f1044..594fe3ef2eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5952.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5952.json
@@ -1 +1 @@
-{"null": 4.843626274582155}
\ No newline at end of file
+{"KEPPRA": 6.912020216649908, "null": 4.13739165076555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5953.json
index b14c67a4fb2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5953.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5953.json
@@ -1 +1 @@
-{"CICLOSPORIN": 12.14502353871776, "PEGASYS": 7.2797245048246015, "null": 3.1376920967560387}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5954.json
index b2fbc74c41c..dbe024f862b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5954.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5954.json
@@ -1 +1 @@
-{"ACLASTA": 83.46835268608572, "BONVIVA": 53.53767787315208, "CELLCEPT": 6.060786009989613, "FORSTEO": 5.9543516813421, "NEXAVAR": 4.8747877273999, "OCRELIZUMAB": 99.13066707064216, "ROACTEMRA": 12.130229887250422, "SIMPONI": 5.141914925284588, "STELARA": 5.941926689676518, "SUTENT": 1.1977625149685909, "XELJANZ": 2.3810781968613}
\ No newline at end of file
+{"null": 2.829369566940733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5955.json
index c9fb2140150..1358ee9da2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5955.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5955.json
@@ -1 +1 @@
-{"FORSTEO": 28.586770555592462}
\ No newline at end of file
+{"LOXAPINE": 532.6009034077952, "VILDAGLIPTIN": 382.4531151659439, "null": 1.8293752978045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5956.json
index d4b2b45ac1e..6a0a5c0acc3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5956.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5956.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.5006361622624202, "ABATACEPT": 6.140323854067137, "ACLASTA": 8.714316233681705, "ADALIMUMAB": 3.172244840762692, "AMINOSALICYLIC": 1.556764449641496, "ANAKINRA": 1.2338677162705716, "APIDRA": 1.2133952191870627, "APREMILAST": 2.873053991334549, "APROVEL": 1.2625267256664952, "ARAVA": 4.000949170567793, "ATRIPLA": 7.662655291517863, "AVONEX": 5.473311161671718, "BONVIVA": 1.9503601701733309, "BYDUREON": 1.2387684893647088, "BYETTA": 2.7011947326082164, "CANNABIDIOL": 6.11201945184307, "CELECOXIB": 4.341118862648496, "CIMZIA": 1.534713889779983, "COSENTYX": 4.137215310531088, "CRIXIVAN": 3.286303745960675, "CYMBALTA": 2.554901501703663, "DULOXETINE": 3.0157357219979115, "ELIQUIS": 1.3645294394965062, "EMPAGLIFLOZIN": 2.3215074124233177, "ENBREL": 5.372996052040717, "ERELZI": 8.688903727005318, "EVENITY": 1.6190606987034704, "EVISTA": 2.7356626835918183, "EXFORGE": 2.157010251250268, "FAMPYRA": 1.6453182583462065, "FASLODEX": 1.0043873300634345, "FIRDAPSE": 1.4189665195007055, "FORSTEO": 3.5436182546070243, "GALVUS": 2.8716166591156584, "HUMALOG": 1.19418840472002, "HUMIRA": 6.177999485760927, "HYDROCORTISONE": 2.1989195427880563, "IBRANCE": 1.0645468146631822, "ISENTRESS": 1.090344302885995, "JANUMET": 4.729625013115848, "JANUVIA": 3.746527455364527, "KISQALI": 1.1290530809237207, "KIVEXA": 4.465408946100279, "LANTUS": 1.0233419878876469, "LEFLUNOMIDE": 7.81704667384628, "LYRICA": 1.405416270653645, "METHOTREXATE": 7.782439049524688, "OPTIMARK": 1.2222704839540914, "ORENCIA": 11.016220108711304, "PANTOPRAZOLE": 2.063673387923775, "PROLIA": 5.216499118007124, "RASILEZ": 1.3010894862587328, "REMICADE": 1.6227975737480378, "RINVOQ": 2.8362530455011776, "SIMPONI": 2.9188609494900883, "STRIBILD": 4.125715809934811, "TRUVADA": 4.618559494639511, "VIREAD": 2.467252235641249, "XELJANZ": 6.08990563761232, "XYREM": 1.361680769786647, "ZOSTAVAX": 8.998382647059312}
\ No newline at end of file
+{"BORTEZOMIB": 110.2097281671077, "COMIRNATY": 0.1426784883467695, "VAXZEVRIA": 0.1571227412858497, "null": 2.4397847507961226}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5957.json
index 22cbf15187e..579996904f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5957.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5957.json
@@ -1 +1 @@
-{"null": 2.441393592880345}
\ No newline at end of file
+{"ABACAVIR": 0.558584443079469, "ABRAXANE": 23.78003164441682, "ACETYLSALICYLIC": 59.72216539564591, "AFINITOR": 3.268256810997209, "ALIMTA": 2.0094844354584547, "ALOXI": 23.469966448367465, "AMINOSALICYLIC": 1.2080809387372742, "ARAVA": 0.7180246498921214, "ARIPIPRAZOLE": 3.137227338577804, "ASPARAGINASE": 3.478961303036884, "AVASTIN": 1.278574164105399, "AXITINIB": 3.743170092411594, "BEVACIZUMAB": 1.4190215045577923, "BUSULFAN": 0.9200491518046924, "BYDUREON": 3.281837822268007, "BYETTA": 1.5778804474880963, "CABOMETYX": 1.6652940384627886, "CALCIUM": 62.20750315514399, "CAPECITABINE": 1.7358017959772196, "CEFTAROLINE": 129.91825049650234, "CELLCEPT": 0.4687013276037889, "CICLOSPORIN": 0.7585504808091478, "CLOPIDOGREL": 0.7632910154100095, "COMIRNATY": 0.1863204825952303, "CYMBALTA": 1.0151597787550355, "CYTARABINE": 2.546276862235616, "DACLATASVIR": 6.911485154585296, "DEXAMETHASONE": 0.919023515594916, "DOCETAXEL": 1.6451598169217605, "ELIQUIS": 0.2144930724722074, "EMPAGLIFLOZIN": 3.110412544317012, "ENTRESTO": 0.7019028726739495, "ENTYVIO": 0.7545299292674669, "EPIVIR": 2.760550249175187, "ESBRIET": 2.217901996431225, "EXJADE": 3.079688626183204, "FASENRA": 1.1445163395182347, "FASLODEX": 0.8052530240880512, "FENTANYL": 1.3181122120132551, "FIRDAPSE": 6.011332075825327, "FORSTEO": 1.3623557282630554, "FORXIGA": 2.60856795859727, "GARDASIL": 0.6703118074772946, "HERCEPTIN": 1.6848636232384226, "HUMALOG": 2.138222404812998, "HUMIRA": 1.9587202386533784, "IBRANCE": 0.5672747643908952, "IBUPROFEN": 1.4613735038506217, "INLYTA": 2.5742421675407163, "INSULIN": 1.0121050257226043, "IPILIMUMAB": 1.7673224108016343, "IRBESARTAN": 3.96570591413869, "IRESSA": 1.2706988285001797, "IRINOTECAN": 2.190832131986965, "JANUMET": 0.8400024969148264, "JANUVIA": 1.1045538104205253, "JARDIANCE": 6.066650143344289, "KAFTRIO": 1.6384428812588436, "KALETRA": 2.3748300478915567, "KEPPRA": 0.8091796485935734, "KEYTRUDA": 1.8452801134286805, "LANTUS": 0.2443020488405892, "LEVETIRACETAM": 1.1968330851843232, "LEVOFLOXACIN": 0.5346629231340668, "LONSURF": 2.41741965171428, "LYNPARZA": 1.7468486134123788, "LYRICA": 0.5598928175219646, "METFORMIN": 5.958762500351369, "MICARDIS": 1.488384076728096, "MMRVAXPRO": 1.269905497530626, "NEULASTA": 1.422812046790636, "NEXAVAR": 1.4028990341368934, "NIMENRIX": 1.2797970676426569, "OFEV": 4.469428165076442, "OLANZAPINE": 3.0590796376534364, "OMALIZUMAB": 2.0113416084135287, "OPDIVO": 0.9201660217764436, "OPSUMIT": 0.4671956784765484, "PANTOPRAZOLE": 1.9179479676527973, "PEGASYS": 1.2046630544598265, "PEGINTERFERON": 1.165128328053902, "PEGINTRON": 1.620009135387254, "PEMBROLIZUMAB": 1.1808255950172324, "RINVOQ": 1.5210155503516007, "ROTATEQ": 15.891236686506671, "RUBRACA": 11.623187792810995, "SAXENDA": 1.3900453952344227, "SOLIRIS": 0.610563830908434, "SOMATROPIN": 6.471100344467632, "SPIKEVAX": 0.2380912520202516, "SPIRONOLACTONE": 3.998935340894473, "STIVARGA": 2.9216083736855487, "SUTENT": 4.352298907860018, "SYNAGIS": 9.238132289677166, "TAGRISSO": 2.2703870435921254, "TAMIFLU": 1.194042476230433, "TOZINAMERAN": 0.2810338692082868, "TRULICITY": 3.879379726599245, "VAXZEVRIA": 0.0936971228336967, "XALKORI": 1.8863328842668208, "XOLAIR": 0.6079676195920817, "XTANDI": 1.942318334635496, "ZOSTAVAX": 0.4508929546681834, "ZYPREXA": 0.9598594559204272, "null": 1.1440924980794889}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5958.json
index ad9a8d855c5..2b6a5b62729 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5958.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5958.json
@@ -1 +1 @@
-{"null": 1.4012002052499064}
\ No newline at end of file
+{"EPIVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5959.json
index 031785b5b26..90c16e96e1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5959.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5959.json
@@ -1 +1 @@
-{"null": 1.0786987957213037}
\ No newline at end of file
+{"ABACAVIR": 3.717831182234173, "ADALIMUMAB": 0.1730302573336016, "AFINITOR": 2.031146082066013, "ARANESP": 62.26293876340647, "ATAZANAVIR": 5.92117155958121, "ATRIPLA": 1.4041209719124357, "BEVACIZUMAB": 2.074303396662024, "CELLCEPT": 1.3389962057651463, "COMBIVIR": 4.32014210436532, "COMIRNATY": 0.01639235666856, "DEXAMETHASONE": 1.2897754889204447, "EMTRICITABINE": 18.33753547871697, "ENTECAVIR": 83.70592078534567, "EXJADE": 5.706767815221547, "FILGRASTIM": 6.124584341366077, "FIRDAPSE": 5.68891863279898, "GENVOYA": 15.986854278908874, "H2": 705.89987823997, "HARVONI": 3.0594080189507435, "HEPSERA": 389.2838046527665, "HYDROCORTISONE": 6.920905188139471, "JARDIANCE": 1.1445176749857708, "KALETRA": 12.547630196477364, "LEVETIRACETAM": 1.5159001115524982, "LOPINAVIR": 18.21857133765413, "MEKINIST": 1.6907905907111538, "METHOTREXATE": 1.2185066656076575, "MIMPARA": 11.28326852222456, "NEXAVAR": 9.03541799987023, "NORVIR": 9.305293571570456, "STIVARGA": 5.704116111091675, "STRIBILD": 0.9784646645148456, "SUTENT": 0.5617038057085327, "TASIGNA": 1.754851321694369, "TENOFOVIR": 127.26828519478757, "TRUVADA": 4.832732673545217, "VIREAD": 70.21664773013512, "null": 0.4572929486776483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/596.json
index 1928fd38743..5acba8aefb0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/596.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/596.json
@@ -1 +1 @@
-{"ALDARA": 64.92981737708975, "EVRA": 76.84951553435127, "QUTENZA": 82.97038620744593, "SIMPONI": 4.7684549251202935, "null": 10.273378247491229}
\ No newline at end of file
+{"ENTYVIO": 16.05574363502386, "NEXAVAR": 4.795745054407323, "SUTENT": 8.107322616792056, "null": 1.8894849396655644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5960.json
index 8e74e6a0a05..15fee68fed0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5960.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5960.json
@@ -1 +1 @@
-{"ABACAVIR": 7.523871228005273, "ADENURIC": 71.51681785343544, "ATRIPLA": 2.5701721111532385, "STRIBILD": 9.733075617096606, "TRUVADA": 2.885117636957224}
\ No newline at end of file
+{"HEPSERA": 1033.3298314677031, "TENOFOVIR": 846.721781779316, "VIREAD": 118.74644814920156, "null": 0.3113889811090267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5961.json
index dd3fb452f01..8bfd52f2757 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5961.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5961.json
@@ -1 +1 @@
-{"ATRIPLA": 2.585485204882509, "KALETRA": 42.532756143564455}
\ No newline at end of file
+{"AXITINIB": 17.30020283967958, "BRAFTOVI": 5.755737250224573, "IPILIMUMAB": 486.2967077921366, "KEYTRUDA": 39.63700463116541, "NIVOLUMAB": 43.702356243315045, "OPDIVO": 166.2949415065339, "PEMBROLIZUMAB": 41.52946791044046, "YERVOY": 349.16454064114987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5962.json
index 97c3b168333..ab3513c39e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5962.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5962.json
@@ -1 +1 @@
-{"ADENURIC": 49.3448447442696, "ARAVA": 5.403231900069628, "CAPECITABINE": 16.195629681325563, "CARFILZOMIB": 78.98700905819479, "CICLOSPORIN": 5.808811301899119, "FULVESTRANT": 16.755677717001202, "NEXAVAR": 5.407297025091355}
\ No newline at end of file
+{"BRAFTOVI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5963.json
index 07eb2f94cbc..633eb30fe2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5963.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5963.json
@@ -1 +1 @@
-{"ADENURIC": 508.8565670154496}
\ No newline at end of file
+{"AXITINIB": 34.93162137773945, "COMIRNATY": 0.0420067198777217, "IPILIMUMAB": 88.60814365829427, "KEYTRUDA": 53.13167654906784, "OPDIVO": 224.7886056633029, "PEMBROLIZUMAB": 11.89062836850796, "YERVOY": 131.1982648591851, "null": 0.3258451226083819}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5964.json
index f17219fe4f1..5a9b7aeb9a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5964.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5964.json
@@ -1 +1 @@
-{"ATRIPLA": 34.368516648652104, "ENTECAVIR": 48.0659823795009, "HEPSERA": 645.4999120606287, "KALETRA": 4.4159530769092905, "LOPINAVIR": 18.556647484457045, "STRIBILD": 15.30060678883252, "TENOFOVIR": 99.17814845409876, "TRUVADA": 27.71823713318533, "VIREAD": 68.067425460411}
\ No newline at end of file
+{"null": 4.138263340504558}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5965.json
index eada890c09a..8fd1887715a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5965.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5965.json
@@ -1 +1 @@
-{"ACLASTA": 17.399752673986765, "AFINITOR": 1.2311857321237674, "ATRIPLA": 1.663665458779212, "AUBAGIO": 1.3994425825370564, "BENLYSTA": 2.4460211871849213, "BONVIVA": 44.95133363244908, "BUPRENORPHINE": 1.7682247841566554, "CABOMETYX": 1.873569332801892, "CELECOXIB": 10.537403215361934, "CELLCEPT": 2.473218546425137, "CICLOSPORIN": 1.8328442825235016, "CIMZIA": 1.711889547394348, "COSENTYX": 1.4603841175585597, "CUBICIN": 21.84415709602437, "CYMBALTA": 1.12701013406488, "CYTARABINE": 1.2319639077559383, "DASATINIB": 11.691476398155068, "DEXAMETHASONE": 2.252321052507341, "ENBREL": 2.274862927741641, "ENTYVIO": 1.1138287921875778, "EVENITY": 5.840069245667778, "FASLODEX": 1.6383653003815348, "FORXIGA": 1.2602299411764972, "HIZENTRA": 3.664592450902416, "HUMALOG": 6.063820391767351, "IBRANCE": 2.646834346981601, "INLYTA": 1.9188432856807296, "INSULIN": 2.7158868217062246, "INVOKANA": 148.59832760374488, "JANUMET": 1.5317828923418777, "JARDIANCE": 4.389947286909426, "JEVTANA": 5.034794245238509, "LANTUS": 3.1301743731143272, "LEVEMIR": 2.376699498403231, "LYRICA": 1.7070009138208864, "METHOTREXATE": 2.573782797896816, "MYCOPHENOLATE": 2.723360144273229, "OPTIMARK": 3.578151098040038, "PEGASYS": 1.2802227138076987, "RINVOQ": 1.814794128458656, "ROACTEMRA": 6.09917260942971, "SIMPONI": 5.52061225692662, "SOLIRIS": 1.6451431969397745, "STELARA": 2.7519021333146845, "SUBOXONE": 1.0054714866719665, "TRUVADA": 1.257958639632978, "VFEND": 1.4649248889540558, "XELJANZ": 4.74128264592438, "XOLAIR": 1.0163817996319788, "ZOMETA": 35.10675871764828}
\ No newline at end of file
+{"null": 9.651085513909733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5966.json
index c0812a66a42..265773c8920 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5966.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5966.json
@@ -1 +1 @@
-{"INVOKANA": 466.94296709079504}
\ No newline at end of file
+{"null": 5.727609753124543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5967.json
index dd85062df67..ba178f095e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5967.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5967.json
@@ -1 +1 @@
-{"ASPARAGINASE": 1.4531348214947697, "ATRIPLA": 53.32525997511447, "BIKTARVY": 1.59103135564877, "BONVIVA": 4.964407359658485, "CRIXIVAN": 2.5995832428780936, "CYTARABINE": 1.3508517399411475, "EFAVIRENZ": 1.274630317693099, "EMTRICITABINE": 1.1768909273082049, "EMTRIVA": 2.189586290976137, "EPIVIR": 2.667810004557924, "GENVOYA": 3.2009706595492253, "INDINAVIR": 2.0354347674550377, "INVIRASE": 3.397353505165784, "ISENTRESS": 2.1202904779640805, "KALETRA": 10.440469673963497, "KIVEXA": 1.9886344521846984, "LOPINAVIR": 2.0338300867947376, "NORVIR": 2.3158143652694068, "OCEAN": 11.797922540172449, "REYATAZ": 3.5002651700339324, "RITONAVIR": 2.06848121012976, "STRIBILD": 40.16079280889993, "TENOFOVIR": 1.072512863071379, "TESTOSTERONE": 3.1980220199220595, "TRUVADA": 60.90031088752984, "VIREAD": 15.360986277732517, "ZOMETA": 5.591603834989503}
\ No newline at end of file
+{"ADALIMUMAB": 5.766419070385762, "BUPIVACAINE": 9.754796598050056, "COMIRNATY": 0.5867715106300094, "FENTANYL": 3.9355447450581336, "GARDASIL": 1.4801667311173543, "IBUPROFEN": 3.6924967073905592, "KEPPRA": 1.0311885925068407, "LEVETIRACETAM": 1.5114519186744124, "MIDAZOLAM": 4.0205013864427706, "OCRELIZUMAB": 3.103791315509961, "OLANZAPINE": 0.9279293323311506, "OPSUMIT": 1.1752274216220515, "PANTOPRAZOLE": 7.8231022067609155, "SPIKEVAX": 0.7780288884859464, "SUBOXONE": 2.940472907760595, "TOZINAMERAN": 2.7965479484497857, "VAXZEVRIA": 1.3796245105213245, "XOLAIR": 1.59959260588685, "null": 1.105338389605195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5968.json
index e3a2bdd83df..047fd2cfac2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5968.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5968.json
@@ -1 +1 @@
-{"ACLASTA": 48.64531299490949, "ACLIDINIUM": 17.730997735917917, "AFINITOR": 13.30002107270266, "ALIMTA": 3.544968527356245, "AVASTIN": 5.62825923534458, "AXITINIB": 10.442535568322572, "BEVACIZUMAB": 4.929753772125436, "BONDRONAT": 458.2330193518784, "BONVIVA": 500.44137319738974, "BORTEZOMIB": 6.0937859417738895, "CABAZITAXEL": 17.032282791715605, "CABOMETYX": 22.022776711413727, "CAPECITABINE": 4.17964592395439, "DARZALEX": 6.340162451585181, "DENOSUMAB": 67.39420292653622, "DEXAMETHASONE": 3.844903863000716, "DOCETAXEL": 3.952831959644103, "EVENITY": 79.22637126581128, "EVISTA": 9.774382602494402, "FASLODEX": 5.800514772958016, "FORSTEO": 2.78173828062088, "FOSAVANCE": 240.23676751424856, "FULVESTRANT": 10.949193842622188, "IBRANCE": 8.663465993503198, "INLYTA": 3.691279153893254, "JEVTANA": 12.055093389380763, "LENVIMA": 7.223543500335463, "NEXAVAR": 2.549461265328836, "PEMETREXED": 4.687289583030724, "PROLIA": 24.149922892268723, "SORAFENIB": 14.70981260897226, "SUNITINIB": 86.25154931662397, "SUTENT": 12.097106933796264, "THALIDOMIDE": 12.31537943769507, "VOTRIENT": 2.294451649629253, "XGEVA": 189.02555822628665, "XOFIGO": 41.595890843858456, "XTANDI": 1.7516935568683112, "ZOLEDRONIC": 390.7119213060007, "ZOMETA": 194.4531119845519}
\ No newline at end of file
+{"AMIKACIN": 26.12155459479332, "CELLCEPT": 5.54343016885066, "CICLOSPORIN": 4.089876907679058, "CLOPIDOGREL": 2.0212552326328943, "NEXAVAR": 3.3533500723636074, "STIVARGA": 6.983315686377209, "SUTENT": 1.2773198071569565, "null": 1.550942721237803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5969.json
index eebe1bcf617..b493121afdd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5969.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5969.json
@@ -1 +1 @@
-{"ACLASTA": 6.537883717501369, "ATRIPLA": 68.31019063939806, "DESCOVY": 2.8386089925677567, "EFAVIRENZ": 2.1395532168954507, "EMTRICITABINE": 4.308766513322853, "EVEROLIMUS": 1.4905730651446891, "ISENTRESS": 1.614414116016283, "KALETRA": 3.622578632293048, "LOPINAVIR": 2.5747566297293845, "NORVIR": 1.119849155520688, "STRIBILD": 31.278487027827527, "TENOFOVIR": 5.189291991228509, "TIVICAY": 3.734166142319564, "TRUVADA": 39.595588742731046, "VIREAD": 22.847655999828397, "ZOSTAVAX": 2.185507406751505}
\ No newline at end of file
+{"null": 14.441275245163482}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/597.json
index f70845fa238..14ae06efdf8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/597.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/597.json
@@ -1 +1 @@
-{"null": 7.208495727880573}
\ No newline at end of file
+{"VAXZEVRIA": 5.109876098179467, "null": 0.607446179040787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5970.json
index dd829cd2c05..114df2d38e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5970.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5970.json
@@ -1 +1 @@
-{"ACLASTA": 3.124835017382656, "ADEFOVIR": 4.717083502807063, "ALENDRONATE": 13.441191236542306, "ALPELISIB": 1.567821272203524, "APIXABAN": 1.0344198989941722, "ATRIPLA": 48.2989046874149, "CANAKINUMAB": 10.236979833369356, "DACLATASVIR": 1.0950671484377636, "DARUNAVIR": 3.1109798076540023, "DENOSUMAB": 1.2544679777815582, "DESCOVY": 2.990841928683331, "EMTRICITABINE": 2.154773322619436, "EMTRIVA": 1.9278820986676144, "ENBREL": 1.2536726735599495, "ENTECAVIR": 1.0078273375303166, "EVISTA": 3.002512697810034, "GENVOYA": 3.61735310944852, "HEPSERA": 7.13236119592556, "INOVELON": 7.736049387581538, "INTELENCE": 1.5616221383187854, "KALETRA": 6.879071022701591, "KIVEXA": 2.5657577985167404, "LOPINAVIR": 1.856522690442476, "MIRABEGRON": 2.106147722018445, "NORVIR": 6.157647300067522, "PROLIA": 1.839799536988984, "RITONAVIR": 2.257155108783413, "SPIRONOLACTONE": 1.2838510275487738, "STRIBILD": 31.576430709141217, "TENOFOVIR": 8.634721512900589, "TIVICAY": 1.0768109493851492, "TRUVADA": 44.003572877467015, "VEMLIDY": 2.444969294416385, "VIREAD": 22.156577081776984, "ZOSTAVAX": 1.2410130859617958}
\ No newline at end of file
+{"BEOVU": 73.94804861967218, "DEXAMETHASONE": 15.011903548774782, "EYLEA": 480.09103713237, "TOBRAMYCIN": 63.85817046197631, "null": 1.522592979177992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5971.json
index d4faa298b05..51915884b21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5971.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5971.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.531075424269411, "ATRIPLA": 25.654815836290396, "CICLOSPORIN": 3.12623403840072, "EVISTA": 13.810657763091127, "FORSTEO": 5.802024149413668, "STRIBILD": 4.512159499609686, "TRUVADA": 19.467346146552988}
\ No newline at end of file
+{"ARIPIPRAZOLE": 3.149246415808347, "ASPARAGINASE": 7.198618205930351, "AUBAGIO": 3.755420734858288, "BUDESONIDE": 2.072957071479217, "CICLOSPORIN": 2.3100907486691926, "COMIRNATY": 0.4682951203292085, "GARDASIL": 4.060867572764426, "JANUVIA": 3.015272438536037, "LEVETIRACETAM": 2.5758231206481925, "LYRICA": 2.717902286339948, "MELATONIN": 17.36902265085328, "OLANZAPINE": 2.223352797263866, "SHINGRIX": 1.8030134587351163, "SPIKEVAX": 0.3224195688013975, "TOZINAMERAN": 0.3193935492297433, "VAXZEVRIA": 0.3080732167763091, "null": 2.2208079712464355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5972.json
index fe284a98c17..d5329e8a95c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5972.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5972.json
@@ -1 +1 @@
-{"METHOTREXATE": 19.1398421968342, "NEXAVAR": 8.099751990899538, "THIOTEPA": 502.9693174763792}
\ No newline at end of file
+{"AZILECT": 82.41361293303027, "BEXSERO": 61.05668844628617, "COMIRNATY": 0.3838260156233337, "INFANRIX": 28.803101408203595, "MMRVAXPRO": 4.631635040947092, "NIMENRIX": 18.797493621394835, "PREVENAR": 33.28122562400783, "SPIKEVAX": 0.5811127714266748, "null": 1.8215520627676296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5973.json
index a21bcca84e4..3877b3182b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5973.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5973.json
@@ -1 +1 @@
-{"PAZOPANIB": 862.0287985077421}
\ No newline at end of file
+{"COMIRNATY": 1.888978514597675, "OMALIZUMAB": 5.218218186227153, "SPIKEVAX": 1.7812838891415514, "TOZINAMERAN": 0.8850306658665014, "VAXZEVRIA": 0.9577412457356064, "null": 1.0067498174240062}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5974.json
index 6c6e5142b95..d2f6ba5e730 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5974.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5974.json
@@ -1 +1 @@
-{"ARAVA": 4.079493885432548, "ENBREL": 8.135285920525464, "FULVESTRANT": 28.43729889478194, "LEFLUNOMIDE": 43.03121409068424}
\ No newline at end of file
+{"KALETRA": 5.774025128155651, "KEPPRA": 4.902013659480922, "null": 7.863371366201184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5975.json
index fabcc419095..1e5b86c3084 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5975.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5975.json
@@ -1 +1 @@
-{"RINVOQ": 441.3242238122656}
\ No newline at end of file
+{"null": 1.6707413842154883}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5976.json
index 9d8568df1d4..8a675fdac11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5976.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5976.json
@@ -1 +1 @@
-{"COSENTYX": 10.757771677203424, "GARDASIL": 3.267371003436215, "PEGASYS": 1.9196575716302584, "STELARA": 5.734648203180128, "ZOSTAVAX": 12.10889728270801}
\ No newline at end of file
+{"null": 3.0769930326174477}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5977.json
index a74d0b9931d..616457c7093 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5977.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5977.json
@@ -1 +1 @@
-{"AIMOVIG": 23.196685106510127, "AMIKACIN": 9.069150587417631, "BOTULINUM": 19.618845686512465, "CELLCEPT": 2.563018743769575, "COMBIVIR": 7.929004504899535, "COSENTYX": 2.273908166734489, "CYTARABINE": 2.909983131892154, "DELAMANID": 22.79196815930085, "INCIVO": 4.32768758828345, "INFANRIX": 39.20311069576132, "MEPOLIZUMAB": 2.5308737787287137, "MMRVAXPRO": 14.109401929844422, "NUCALA": 2.0306372571671405, "PEGASYS": 1.1883250228894664, "PREVENAR": 17.971332406303574, "ROACTEMRA": 2.2840760977104293, "ROTATEQ": 8.663267440188225, "SYNAGIS": 25.09467310992204, "SYNFLORIX": 171.24733030314465, "ZOSTAVAX": 3.287192828625292, "null": 1.5686403594560938}
\ No newline at end of file
+{"null": 6.781126114714091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5978.json
index 7b943c94ff0..ec60c547f02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5978.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5978.json
@@ -1 +1 @@
-{"GARDASIL": 6.424575725180661, "MMRVAXPRO": 19.158406091721755, "ZOSTAVAX": 7.778919171669348, "null": 1.0454954131483345}
\ No newline at end of file
+{"ABACAVIR": 0.175356731946918, "ABATACEPT": 0.031029374127585, "ABILIFY": 0.7364117182294525, "ABRAXANE": 0.3800856401555691, "ACLASTA": 1.243766833050426, "ACTOS": 0.4923721587070559, "ACTRAPID": 0.7901296725083298, "ADALIMUMAB": 0.1761663974112645, "ADCIRCA": 2.422573634373008, "ADEMPAS": 6.084132914511892, "ADENURIC": 1.2838408786075444, "ADVAGRAF": 0.8434144332027089, "AERIUS": 1.3221847763576575, "AFINITOR": 0.4568662286063565, "AFLIBERCEPT": 1.0113919688544477, "AIMOVIG": 0.9717004430541324, "ALEMTUZUMAB": 0.5711324914832122, "ALIMTA": 0.6066304040694714, "ALISKIREN": 0.7957886204367655, "AMBRISENTAN": 2.117189430207232, "AMBROXOL": 12.837664357602002, "AMIKACIN": 0.9979577299675446, "AMINOSALICYLIC": 0.3611683763281043, "AMLODIPINE": 11.708290053400296, "ANAKINRA": 0.4894393302300822, "ANGIOX": 3.675187308095426, "ANORO": 0.1421783031034296, "ANTIBIOTICS": 0.6353801605675201, "APIDRA": 0.3683906283282817, "APIXABAN": 0.5206205577462028, "APREMILAST": 0.2907604558650292, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5979.json
index 51ce0372d6d..a18aaaea42d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5979.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5979.json
@@ -1 +1 @@
-{"NUCALA": 12.192410014874737, "null": 2.017758176683172}
\ No newline at end of file
+{"COMIRNATY": 1.3519629862874958, "null": 0.6695999608341691}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/598.json
index 5ec3e4d28fe..a3efe8eb63c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/598.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/598.json
@@ -1 +1 @@
-{"null": 41.06112461163088}
\ No newline at end of file
+{"ABILIFY": 268.98576278857007, "null": 0.5610331033905649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5980.json
index 0194702ed38..f390ddc247d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5980.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5980.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7862105792281946}
\ No newline at end of file
+{"null": 6.267647605368683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5981.json
index cda756fc5c4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5981.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5981.json
@@ -1 +1 @@
-{"null": 1.51951164243297}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5982.json
index ec194d490fb..2c5e3b0df06 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5982.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5982.json
@@ -1 +1 @@
-{"null": 4.79129469592632}
\ No newline at end of file
+{"BUDESONIDE": 16.515169332122458, "HYDROCORTISONE": 96.50531063051272, "null": 3.0843551270831253}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5983.json
index 9358e16fe00..312d21a1c8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5983.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5983.json
@@ -1 +1 @@
-{"ALIMTA": 7.685290052827204, "AMIKACIN": 275.40436637700014, "AMINOSALICYLIC": 22.31138591229001, "CASPOFUNGIN": 35.92219244618255, "CICLOSPORIN": 3.029860238373207, "PEMETREXED": 31.348768565678352, "TOBRAMYCIN": 174.24190923011594, "null": 2.523492912438566}
\ No newline at end of file
+{"COMIRNATY": 0.063316131008878, "IPILIMUMAB": 17.266786365829507, "KEYTRUDA": 33.389316598495235, "OPDIVO": 61.05255206910652, "YERVOY": 56.0289313002347, "null": 1.4726555410667108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5984.json
index 2bc6e5b7b5c..525a6b05707 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5984.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5984.json
@@ -1 +1 @@
-{"KYMRIAH": 994.662270761931, "null": 1.214010444928523}
\ No newline at end of file
+{"ABILIFY": 2.726087495545264, "ACTRAPID": 4.73765141438557, "ARIPIPRAZOLE": 1.5817896330177907, "BEDAQUILINE": 5.670450922014624, "BEXSERO": 13.365963223585394, "BRIDION": 5.165073722305402, "BUPIVACAINE": 2.9087501930525743, "BUPRENORPHINE": 0.9959499877302128, "CHAMPIX": 0.4254469716068297, "CLOPIDOGREL": 0.7494155518673234, "COMIRNATY": 0.4461013702813187, "CYMBALTA": 0.424814391017642, "DULOXETINE": 1.7020221440356955, "ELIQUIS": 0.3842704771979246, "EUCREAS": 7.131139310790509, "FENTANYL": 3.5460266463336683, "FLEBOGAMMA": 3.83884042865582, "FYCOMPA": 11.451326894691636, "HUMALOG": 0.5495002800853699, "IBUPROFEN": 1.0825092551322562, "INSULIN": 0.8343149123043871, "JANUMET": 0.8451310112538392, "KEPPRA": 3.33014939125787, "KEYTRUDA": 0.2995557989610362, "KYMRIAH": 1.59266102512166, "LANTUS": 1.6638148521738794, "LEVEMIR": 1.4526986289615995, "LEVETIRACETAM": 1.277760969005875, "LEVODOPA": 8.659507732707416, "LYRICA": 1.3482422528177074, "MIDAZOLAM": 3.0008491981819256, "MMRVAXPRO": 1.630564052320442, "OLANZAPINE": 7.957037005582945, "PEGASYS": 0.2101646110103656, "PREGABALIN": 2.250537572696859, "PRIVIGEN": 2.375798491582636, "RISPERIDONE": 4.774712848697141, "SPIKEVAX": 0.3423729543009303, "SUTENT": 0.2226403375514616, "TAMIFLU": 13.519531127114258, "TOZINAMERAN": 0.578000077258397, "VAXZEVRIA": 0.5998145447901307, "ZYPREXA": 4.182162221453252, "null": 2.3324347440189683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5985.json
index f6b9fde876d..9b9f1afc8d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5985.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5985.json
@@ -1 +1 @@
-{"null": 1.1927577248925028}
\ No newline at end of file
+{"null": 2.4797871277346024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5986.json
index a8e54906b24..4d6f01073e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5986.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5986.json
@@ -1 +1 @@
-{"BUSULFAN": 1022.0490136637568}
\ No newline at end of file
+{"null": 2.760938441528851}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5987.json
index 5e53a5dbd4f..5183f594e58 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5987.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5987.json
@@ -1 +1 @@
-{"AUBAGIO": 2.058107883122748, "AVASTIN": 4.4598789094008495, "BEVACIZUMAB": 5.372149505499167, "CAELYX": 27.03620824413983, "ELIQUIS": 1.136085593777423, "EVISTA": 21.583699905103146, "FORSTEO": 2.204324663928343, "HUMALOG": 1.2395304217045091, "LANTUS": 1.7543809906085188, "LYNPARZA": 13.922675841615671, "MVASI": 41.772609923864295, "NEULASTA": 5.034572934410719, "NPLATE": 5.093898146353857, "OLANZAPINE": 2.6596420955391373, "ROACTEMRA": 2.2502118498866626, "RUBRACA": 6.22399101680361, "SIMPONI": 2.204509909589928, "STELARA": 1.567612107448176, "XELJANZ": 1.205249274541455, "XOLAIR": 1.3488449966914615, "null": 3.063226128238768}
\ No newline at end of file
+{"ABILIFY": 4.172755177207447, "ACLIDINIUM": 2.0899723832883224, "AFINITOR": 1.084320756887066, "AIMOVIG": 0.5292308444124366, "ALEMTUZUMAB": 1.7341756257206156, "ALIMTA": 0.9619237052383968, "AMIKACIN": 0.8242567185355526, "AMINOSALICYLIC": 2.7019249988418075, "ANORO": 17.998906336397237, "APIXABAN": 17.1716546478448, "ARAVA": 0.1250561341716884, "ARIPIPRAZOLE": 1.40921085436607, "ASPARAGINASE": 0.6552645278613061, "ATAZANAVIR": 0.7127582136162771, "ATEZOLIZUMAB": 5.276465839346902, "AUBAGIO": 0.2271654491205621, "AVASTIN": 0.3452103289448491, "AVELUMAB": 30.30551508517025, "AVONEX": 3.309663239109815, "AXITINIB": 27.569990326732736, "AZATHIOPRINE": 1.5473988896107311, "BAVENCIO": 41.53422504399764, "BEDAQUILINE": 0.6386655658516266, "BETAFERON": 1.043551861108633, "BEVACIZUMAB": 0.3434580634301378, "BIKTARVY": 0.3402434668505212, "BRAFTOVI": 1.2911330994239971, "BUDESONIDE": 0.4324258428104457, "BUSULFAN": 0.5326238189815738, "BYDUREON": 0.6813732684461076, "BYETTA": 2.9668120296031213, "CABOMETYX": 28.96376642823016, "CARMUSTINE": 1.1862846021400446, "CELLCEPT": 0.6673083857467521, "CHAMPIX": 0.4796489304150541, "CICLOSPORIN": 0.1395440350575738, "CIMZIA": 0.1357213799649944, "CLOPIDOGREL": 0.1156902149595899, "COMIRNATY": 0.1358110139635043, "COSENTYX": 0.6192861039626729, "CYMBALTA": 0.3932287769700356, "DELAMANID": 4.614435957586953, "DEXAMETHASONE": 0.323392278466225, "DOXORUBICIN": 0.7962153891874522, "DULOXETINE": 0.5434075922907914, "ELIQUIS": 0.7263420285202392, "ENBREL": 0.4442862646118694, "ENTRESTO": 0.9073082284023696, "EPADERM": 38.0176560464381, "ERLEADA": 9.61074919584059, "ESOMEPRAZOLE": 1.6501748602398187, "EVEROLIMUS": 3.953510726380879, "EVISTA": 0.4863136559833519, "FASLODEX": 1.0819422364390274, "FIRDAPSE": 0.6565765611252559, "FORSTEO": 0.171705802864775, "FORXIGA": 0.4610261845581349, "FOTIVDA": 9.370291237474746, "GARDASIL": 0.6478134260620158, "HERCEPTIN": 0.4383900896639563, "HUMALOG": 0.2929132604425014, "HUMIRA": 1.001845210403555, "HYDROCORTISONE": 0.4486068409971814, "IBRANCE": 0.4101221898092876, "IBUPROFEN": 0.3078086189105619, "ICLUSIG": 1.804502573032024, "INCIVO": 0.4785965893233448, "INLYTA": 12.046258491430343, "INSULIN": 0.5039378260544306, "INTERFERON": 9.94358682446966, "INTRONA": 8.604319828204773, "IPILIMUMAB": 13.434881726666614, "IRINOTECAN": 0.7148714934978111, "JAKAVI": 0.2638351747035258, "JANUMET": 1.2884676230255554, "JANUVIA": 1.2052086283144234, "JARDIANCE": 0.0927926860951158, "KEPPRA": 0.4542927299604189, "KEYTRUDA": 32.009073399516225, "LANTUS": 0.3143887367216421, "LEMTRADA": 8.924267166383311, "LENVIMA": 18.639165602739286, "LEVETIRACETAM": 0.4911948116169075, "LIBTAYO": 16.56030425450857, "LIRAGLUTIDE": 47.62001282654, "LYRICA": 0.7200785092898395, "LYSODREN": 7.792186168294314, "MAVENCLAD": 1.3547007127342592, "METFORMIN": 3.5956081282438097, "METHOTREXATE": 0.5680608413353471, "MITOTANE": 12.78136320557146, "MULTAQ": 0.5015847679553583, "NEXAVAR": 1.7255361596604233, "NILOTINIB": 1.3228742526122073, "NIVOLUMAB": 9.008905793415217, "NUCALA": 0.4127765123992846, "OCEAN": 23.937833835471064, "OLANZAPINE": 0.4041006228338459, "OMALIZUMAB": 0.3020416118556965, "OPDIVO": 19.828938271863997, "OPSUMIT": 0.2916554811098221, "PACLITAXEL": 2.3342781242198027, "PANTOPRAZOLE": 0.3359673111668927, "PAZOPANIB": 7.411496511870068, "PEGASYS": 5.313897539842043, "PEGINTERFERON": 2.484518463119456, "PEGINTRON": 5.864273946906122, "PEMBROLIZUMAB": 16.803681739659414, "PLAVIX": 0.104271887205858, "PREGABALIN": 0.4368252678152333, "PROPRANOLOL": 1.4564133473274845, "REBETOL": 4.474055923788559, "REGORAFENIB": 5.385802107028406, "RIBAVIRIN": 1.064246401715855, "RISPERIDONE": 1.0267117058834736, "RITUXIMAB": 0.3176359411757224, "ROACTEMRA": 0.26313516024621, "RUBRACA": 0.7279641687688718, "SAXENDA": 0.3364447972295311, "SHINGRIX": 0.2465943276665839, "SIMPONI": 0.3750576066370147, "SOLIRIS": 0.1798744286940349, "SOMATROPIN": 1.5047748803994403, "SORAFENIB": 1.8625152058657672, "SPIKEVAX": 0.073320977770649, "SPRYCEL": 0.4784366292875277, "STELARA": 0.4420446908726915, "STIVARGA": 4.873288170592558, "SUBOXONE": 0.3029874385703748, "SUNITINIB": 18.01285600587825, "SUTENT": 8.881013048743606, "TASIGNA": 1.2345912611439478, "TOZINAMERAN": 0.1860910451938659, "TRACLEER": 0.2519176902414579, "TREMFYA": 0.5307963909288149, "TRUVADA": 0.0515950046094057, "VAXZEVRIA": 0.0614695390688257, "VICTOZA": 0.2821609781010221, "VOTRIENT": 4.472125644502695, "XELJANZ": 0.2470169529318978, "XOLAIR": 0.3833285481137221, "XTANDI": 0.2577295130874491, "XYREM": 0.7981528998813188, "YERVOY": 5.031543586318606, "ZOSTAVAX": 3.562944032090234, "ZYPREXA": 0.7247704905620407, "null": 0.8014316689424252}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5988.json
index f1bf00d17c2..a030c52bb9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5988.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5988.json
@@ -1 +1 @@
-{"RUBRACA": 61.51599018863623, "null": 2.2687650005360758}
\ No newline at end of file
+{"ABILIFY": 0.5399717789217768, "ARIPIPRAZOLE": 0.404811668305007, "AVAMYS": 0.7078367866449418, "BEXSERO": 11.683067915618995, "BRIDION": 2.632249551540651, "CHAMPIX": 0.171228414518186, "CICLOSPORIN": 0.3612773935561899, "COMBIVIR": 3.1489404178673763, "COMIRNATY": 1.293660127143306, "COSENTYX": 0.4900929038837848, "CYMBALTA": 0.3750387028653559, "DEXAMETHASONE": 0.7998928919477225, "DEXMEDETOMIDINE": 8.25792394985899, "DULOXETINE": 1.1518411897002612, "ELIQUIS": 0.2341020901395583, "ENTRESTO": 1.1386698331870904, "EPIVIR": 1.522123179340907, "EXFORGE": 0.6590089883433895, "FAMPYRA": 1.236272501671043, "FASLODEX": 0.3968358414140491, "FENTANYL": 0.5149229789662549, "FORSTEO": 0.3639405187327693, "FYCOMPA": 2.877426480812209, "GARDASIL": 2.108442171500678, "GENERAL": 38.23211180675602, "HEXYON": 14.953904631688031, "IBUPROFEN": 0.3579518437095896, "INFANRIX": 29.238684109667965, "INSULIN": 0.3757106588462094, "INVIRASE": 7.922168379135289, "JARDIANCE": 0.2677366760210248, "KEPPRA": 2.4079265017512865, "LANTUS": 0.1253194492900158, "LEVETIRACETAM": 3.6516442257073214, "LEVOFLOXACIN": 0.4674754878293795, "LYRICA": 0.994289929481198, "MENVEO": 4.5665996310314325, "METHOTREXATE": 0.3015430090289211, "MICARDIS": 0.6620974652971134, "MIDAZOLAM": 2.682165010714514, "MMRVAXPRO": 4.533913717995985, "NAGLAZYME": 2.275360063789025, "NIMENRIX": 2.36675622570285, "NOT": 4.338500861353692, "OLANZAPINE": 1.3725722149020765, "PREVENAR": 13.198776932099891, "ROTARIX": 49.32153108343879, "ROTATEQ": 8.507512993472057, "SHINGRIX": 1.4531508308702117, "SPIKEVAX": 1.0301802484761493, "SPINRAZA": 2.3211949837258525, "SUFENTANIL": 3.0338722906143767, "SUTENT": 0.0932644875495714, "SYNAGIS": 4.364772416793054, "SYNFLORIX": 15.49436104679001, "TOZINAMERAN": 0.218218387523523, "TWINRIX": 1.842260213765478, "VALSARTAN": 5.93851096370049, "VAXZEVRIA": 1.2494450005196591, "VIMPAT": 0.8481194540141634, "ZYPADHERA": 3.001666135916481, "ZYPREXA": 0.5461267107134566, "null": 1.6822416163965588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5989.json
index 8b5d65ce68a..cf9682d2fc7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5989.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5989.json
@@ -1 +1 @@
-{"LYNPARZA": 856.9699592211797, "OLAPARIB": 228.7139975240651, "RUBRACA": 719.381654576542}
\ No newline at end of file
+{"FENTANYL": 5.269865358941686, "KEPPRA": 5.598737195292245, "LEVETIRACETAM": 12.020981570990903, "OLANZAPINE": 5.823162045329704, "ZYPREXA": 8.021537254859577, "null": 7.260819686023027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/599.json
index 8fc1cae4a85..7c5594b912b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/599.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/599.json
@@ -1 +1 @@
-{"null": 7.192783404900978}
\ No newline at end of file
+{"null": 6.623521179512259}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5990.json
index 8cff135a518..624d9ce3dad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5990.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5990.json
@@ -1 +1 @@
-{"AFINITOR": 2.738394351629312, "AIMOVIG": 3.138392394705308, "CANNABIDIOL": 18.36312986808593, "CELLCEPT": 10.531921526894331, "CHLORHEXIDINE": 3.990926106543789, "CIMZIA": 1.5686677208202198, "COMIRNATY": 1.115109584308846, "DACLIZUMAB": 621.1673489199251, "ESMYA": 43.09269855841772, "FORSTEO": 1.3706540954211135, "GARDASIL": 7.271329271376039, "GONALF": 35.56144068611211, "JANUVIA": 1.967181420416416, "LYRICA": 1.6013304427992257, "OMALIZUMAB": 1.9753540540381345, "SILDENAFIL": 5.196500991959199, "SIMPONI": 2.248867030538873, "SOLIRIS": 1.543303071411234, "SUBOXONE": 2.2388025567298446, "XELJANZ": 1.1646851765847404, "XOLAIR": 1.6059032923727223, "null": 1.0965107514864638}
\ No newline at end of file
+{"TOVIAZ": 167.9625798856184, "null": 1.1813139140775986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5991.json
index 982242baad8..eecee536519 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5991.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5991.json
@@ -1 +1 @@
-{"GARDASIL": 9.585506318345404, "TOZINAMERAN": 1.4170139542195364}
\ No newline at end of file
+{"BEXSERO": 79.72292340643273, "COMIRNATY": 1.5640769949476214, "GARDASIL": 1.121398815092004, "HEXACIMA": 271.509093342318, "HEXYON": 100.34455324278557, "INFANRIX": 338.5070124109697, "MMRVAXPRO": 36.14993408742078, "NIMENRIX": 11.353942900704736, "NOT": 20.812459476653828, "PREVENAR": 61.23766732362881, "ROTARIX": 158.4509413574325, "ROTATEQ": 34.30344988437864, "SPIKEVAX": 0.2696586819060509, "SYNFLORIX": 157.4062306832819, "VAXZEVRIA": 0.5958486292962825, "null": 1.0435764613927647}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5992.json
index e154b9baf38..681db0fbf07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5992.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5992.json
@@ -1 +1 @@
-{"CIMZIA": 11.159622841328934, "IBRANCE": 7.080428342156689}
\ No newline at end of file
+{"EYLEA": 193.7458312965939, "null": 2.201873852535795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5993.json
index 26ca8f80199..8d16f0f6cfc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5993.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5993.json
@@ -1 +1 @@
-{"GONALF": 1103.8244496017528}
\ No newline at end of file
+{"null": 2.0287274307096745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5994.json
index 0f5665cd4df..92b0750930f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5994.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5994.json
@@ -1 +1 @@
-{"BUSULFAN": 265.69886583984, "GARDASIL": 17.649250192178776}
\ No newline at end of file
+{"ATRIPLA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5995.json
index 4ae3074771e..41f87c440d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5995.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5995.json
@@ -1 +1 @@
-{"GONALF": 304.0913425839392, "null": 1.388842788657508}
\ No newline at end of file
+{"BUSULFAN": 40.703782705163256, "HEPSERA": 1112.684669710175, "null": 0.7417893370486598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5996.json
index 9615bb40e49..ff0e38cc7b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5996.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5996.json
@@ -1 +1 @@
-{"BEMFOLA": 1748.431010687586, "CETRORELIX": 1249.972431842877, "CETROTIDE": 1863.3713266267764, "CHORIOGONADOTROPIN": 1086.6710242053302, "ELONVA": 1163.225652223502, "FOLLITROPIN": 1027.3058360315404, "GANIRELIX": 2008.8510980136048, "GONALF": 2471.5156252129264, "LUTROPIN": 856.7378404412825, "LUVERIS": 1783.289084149633, "ORGALUTRAN": 2249.0641223469383, "OVALEAP": 1564.2258460080902, "OVITRELLE": 1323.0010622929744, "PUREGON": 1145.3262440447318, "RECOMBINANT": 1077.885177931513, "REKOVELLE": 3327.7200146559853}
\ No newline at end of file
+{"ARIPIPRAZOLE": 4.249395425033976, "BRIDION": 65.09472879591365, "BUDESONIDE": 1.143071290049215, "COMIRNATY": 0.273033180229226, "CYMBALTA": 0.7338489843815991, "DEXAMETHASONE": 3.9267794857875473, "FENTANYL": 15.428974977622351, "LACOSAMIDE": 6.940039891958013, "MIDAZOLAM": 31.46657764290041, "NUCALA": 5.314417654709579, "OLANZAPINE": 4.8352000600916565, "OMALIZUMAB": 26.95175352533294, "SPIKEVAX": 0.1941170483442698, "VAXZEVRIA": 0.0624067463747226, "XOLAIR": 9.901946952078251, "ZYPREXA": 2.681014305037764, "null": 2.0839977574097777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5997.json
index 8b54d530bfd..523f18bf14c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5997.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5997.json
@@ -1 +1 @@
-{"ARAVA": 3.824492475410161}
\ No newline at end of file
+{"null": 2.1526103969026127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5998.json
index a697b284042..42cfd26d96c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5998.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5998.json
@@ -1 +1 @@
-{"null": 3.540905648144215}
\ No newline at end of file
+{"ATRIPLA": 1.4821480701588734, "COMIRNATY": 0.2298544307342462, "KEPPRA": 4.322061295997354, "TOZINAMERAN": 0.6998348747690214, "ZOSTAVAX": 5.982062810964349, "null": 1.9653717945593605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5999.json
index d3105f45f49..a17bb107132 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5999.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/5999.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0242884157419665, "ELIQUIS": 26.51688724578051}
\ No newline at end of file
+{"ADCIRCA": 10.658654492853346, "ARAVA": 0.2694092855646761, "ARIPIPRAZOLE": 2.5273165231673445, "BUDESONIDE": 5.965471218526047, "BUMETANIDE": 61.97871648184076, "BYETTA": 2.153618768855323, "COMIRNATY": 0.0232122109593884, "DEXAMETHASONE": 2.5712715781125026, "EMPAGLIFLOZIN": 68.58981438559384, "ENALAPRIL": 71.48626663745546, "ENTRESTO": 6.750063890942708, "FENTANYL": 1.4799088164388972, "FORXIGA": 4.651903423733287, "IBUPROFEN": 1.904696438445606, "IRBESARTAN": 4.608087195934704, "JANUMET": 2.6073597858985464, "JANUVIA": 3.4722612878907597, "JARDIANCE": 12.504959632028855, "MICARDIS": 3.903907657932638, "PEGASYS": 0.8026188469818848, "PEGINTERFERON": 2.757941523948967, "PEGINTRON": 1.8132318772824751, "PLAVIX": 0.9285473690089098, "PREGABALIN": 3.432068939865614, "ROTATEQ": 3.5095967220087267, "SPIKEVAX": 0.0801893806857493, "SPIRONOLACTONE": 15.790695183996773, "SUTENT": 0.5643430718847561, "ZYPREXA": 0.7291586991520186, "null": 2.022282602574025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6.json
index 7ccc182f949..9cf2cbedaea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6.json
@@ -1 +1 @@
-{"CIMZIA": 7.966332062231188, "null": 1.2510304888901662}
\ No newline at end of file
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/60.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/60.json
index 288fdc7b324..fa10849a618 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/60.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/60.json
@@ -1 +1 @@
-{"FENTANYL": 20.64842232043754}
\ No newline at end of file
+{"null": 3.9299292077785366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/600.json
index 91f86280388..75856994525 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/600.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/600.json
@@ -1 +1 @@
-{"ALDARA": 156.95737222410713, "null": 7.26020539786171}
\ No newline at end of file
+{"ACLIDINIUM": 41.7137727036254, "ARANESP": 1161.886993037581, "COMIRNATY": 0.3221136586087892, "DARBEPOETIN": 505.3676511870972, "SPIKEVAX": 0.205861204187672, "VAXZEVRIA": 0.1119957468592714, "null": 0.092010972977106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6000.json
index 6da6e667bec..10955989d2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6000.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6000.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"AMINOSALICYLIC": 3.476290496637614, "CLOPIDOGREL": 3.708077049892244, "COAPROVEL": 7.778062541058603, "COMIRNATY": 0.060611974944798, "CYTARABINE": 1.8537072328777675, "ELIQUIS": 2.7429853819140635, "ENOXAPARIN": 22.148432894673984, "ENTRESTO": 2.0526053614482795, "FENTANYL": 1.6373321997331958, "JARDIANCE": 2.6673873586681736, "LEVOFLOXACIN": 3.104633908140965, "MIDAZOLAM": 5.577473283304134, "NEXAVAR": 0.986155003646874, "NOVOSEVEN": 27.48841974177974, "OPSUMIT": 1.4888390270349308, "PLAVIX": 5.3722670713647815, "TOZINAMERAN": 1.4869545037044862, "VAXZEVRIA": 0.4051904102609179, "XARELTO": 18.02064426702114, "null": 1.7316480043646203}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6001.json
index b0b37c2ba11..778f4aad1f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6001.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6001.json
@@ -1 +1 @@
-{"ABACAVIR": 8.134701076405351, "ABILIFY": 2.333792449099305, "ACETAMINOPHEN/OXYCODONE": 11.59275491568321, "AERIUS": 2.0582694107737427, "AGOMELATINE": 2.7657241129280954, "ALL": 1.883588499187357, "ANGIOX": 2.990223381675826, "ANTIDEPRESSANTS": 7.557112045353668, "ANTIHISTAMINE": 9.465665925996325, "APIDRA": 1.1391467205067414, "APROVEL": 1.4668230306732146, "ARIPIPRAZOLE": 2.728068595657529, "ASENAPINE": 6.218184290427175, "BARBITURATES": 8.749745194088035, "BENZODIAZEPINE": 13.28443762212147, "BENZODIAZEPINES": 11.273215314666494, "BRIDION": 1.8674594809369307, "BRINTELLIX": 2.0170525421968275, "BRIVARACETAM": 9.244613032529807, "BRIVIACT": 5.791951032843361, "BUMETANIDE": 6.872812829955204, "BUPIVACAINE": 3.840925020580722, "BUPRENORPHINE": 14.254464251949674, "BUVIDAL": 2.4082585554776474, "CAFFEINE": 13.805918403104684, "CANCIDAS": 1.6558332425152211, "CANNABIDIOL": 1.7275028873052756, "CARIPRAZINE": 3.214016692650831, "CELECOXIB": 1.0656517568281365, "CELSENTRI": 1.2096773402093874, "CERTAGEN": 79.27662993296236, "CIRCADIN": 4.953701314060728, "COAPROVEL": 1.0104785945146706, "COLISTIMETHATE": 3.398565002869733, "CORTICOSTEROIDS": 1.2612363760228196, "CRIXIVAN": 1.9429987391065835, "CUBICIN": 2.4475557792468874, "CYMBALTA": 1.244263368925177, "DACLIZUMAB": 15.257887090500232, "DESLORATADINE": 2.921857486838308, "DEXMEDETOMIDINE": 2.1573167509016526, "DULOXETINE": 3.808189700567137, "EMTRICITABINE": 1.1246661119295644, "ENALAPRIL": 2.644313198169167, "ENTACAPONE": 1.0271373901371414, "EPIDYOLEX": 5.686020081046888, "ESOMEPRAZOLE": 1.4266815879298698, "EUCREAS": 1.1466345893443215, "FENTANYL": 8.098521277133903, "FESOTERODINE": 31.18354674290772, "FYCOMPA": 1.013078368278619, "GENVOYA": 1.3152756896366955, "GLIBENCLAMIDE": 5.82406378973073, "GLUCAGON": 4.220962392169906, "HERBAL": 4.36787360081528, "IBUPROFEN": 6.146872504657533, "INSULIN": 1.0882164927446114, "INTEGRILIN": 1.8462170565339693, "INVEGA": 2.735138234345458, "IRBESARTAN": 1.3148872062284147, "JANUMET": 1.2667063807266337, "JEVITY": 28.387805474557503, "KEPPRA": 3.3403727416393214, "LACOSAMIDE": 2.695134369652358, "LANTUS": 1.2355291990983974, "LATUDA": 1.0226142319297775, "LEVETIRACETAM": 2.2436122680641586, "LEVODOPA": 2.327211917401294, "LEVOFLOXACIN": 1.264019776670122, "LOXAPINE": 6.888201236158349, "LURASIDONE": 3.9029597959734046, "LYRICA": 2.261127925185482, "MELATONIN": 2.4858812853342624, "MICARDIS": 1.3005501707725604, "MIDAZOLAM": 3.854359542732952, "MIXTARD": 2.180112163946692, "MYCAMINE": 1.523181685519233, "NALOXONE": 18.58924069369474, "NOT": 5.136330255025773, "NOXAFIL": 1.9566172241404969, "OLANZAPINE": 4.315073173179077, "OPIOIDS": 14.344372271990986, "ORENCIA": 1.9263487106413544, "ORGALUTRAN": 5.858271996896808, "OXYBUTYNIN": 1.4958340642058872, "PIOGLITAZONE": 1.6961137676655045, "PRADAXA": 2.42582339372099, "PREGABALIN": 4.651389877313613, "PRIALT": 8.329305050587235, "PROPRANOLOL": 4.717267316909693, "PROQUAD": 6.098810933662947, "RELVAR": 1.2071390981375132, "RUCONEST": 1.2864400927173552, "SEEBRI": 5.28533097805287, "SERTRALINE": 2.7941216912224616, "SIFROL": 2.5762404735889946, "SILDENAFIL": 1.0144642413713856, "SODIUM": 17.66334240346588, "STALEVO": 1.016229597510605, "STOCRIN": 2.905313149425483, "SUBOXONE": 6.698285804535434, "SUFENTANIL": 1.23008147714811, "TAMIFLU": 1.153530844488632, "TEMSIROLIMUS": 4.736074388706919, "TERIPARATIDE": 1.6413003062845126, "TESTOSTERONE": 1.5295746243698338, "TRACTOCILE": 3.1146338112295417, "TRELEGY": 1.168746699445488, "ULTIBRO": 4.575354809980388, "UNKNOWN": 2.1465761918483364, "UNSPECIFIED": 8.639218236813234, "VALDOXAN": 1.9124709718827648, "VELMETIA": 1.8779314548596056, "VFEND": 1.036056119091305, "VIAGRA": 2.18976453470984, "VIMPAT": 4.611095916495148, "VORTIOXETINE": 5.3403495699396695, "XEPLION": 2.8464849965704224, "XYREM": 2.421502865789863, "ZYPADHERA": 2.8951672394409647, "ZYPREXA": 4.436000958492175, "null": 4.267992161622221}
\ No newline at end of file
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6002.json
index 65faef368a2..0e131539576 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6002.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6002.json
@@ -1 +1 @@
-{"null": 1.071962840808923}
\ No newline at end of file
+{"ABRAXANE": 2.816162523260792, "ADCIRCA": 6.086202415632863, "ADEMPAS": 3.897665608226816, "AFINITOR": 2.0754549574311936, "ALEMTUZUMAB": 1.4279152506928994, "ALIMTA": 0.6849271769963801, "AMBRISENTAN": 3.4917185393993955, "AMIKACIN": 4.797577679130017, "ANAKINRA": 0.9577236752023812, "ANORO": 29.44448850019058, "APIXABAN": 4.758532708692389, "APREPITANT": 3.6506345400712936, "ARAVA": 0.0948257333958905, "ARIPIPRAZOLE": 0.6930417564883065, "ASPARAGINASE": 1.7045552983841716, "AUBAGIO": 0.2332613166300926, "AVANDIA": 0.684216318215015, "AZACITIDINE": 1.7720009754355193, "AZATHIOPRINE": 2.294324102895045, "BEVACIZUMAB": 0.4680427267472107, "BORTEZOMIB": 1.0706473222801642, "BRIDION": 11.7304719230179, "BUDESONIDE": 3.897339657108935, "BUPIVACAINE": 3.678711618082422, "BUPRENORPHINE": 1.2585856355460654, "BUSULFAN": 1.869262972924305, "BYETTA": 0.3687227597784004, "CABOMETYX": 0.5035494594516203, "CAELYX": 2.9732175357673745, "CANCIDAS": 1.4635999774643649, "CASPOFUNGIN": 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"XALKORI": 1.5781018496647492, "XELJANZ": 0.1692229970465514, "XOLAIR": 0.7241427404288937, "XTANDI": 0.1743701137306507, "YESCARTA": 8.396987476281254, "ZIAGEN": 5.229033669015095, "ZOSTAVAX": 0.8643334532282378, "ZYPREXA": 1.167905960919598, "null": 1.5528305680612229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6003.json
index 90767084c1d..293271daaa1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6003.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6003.json
@@ -1 +1 @@
-{"ENTYVIO": 56.09709914828749, "null": 1.162750327229765}
\ No newline at end of file
+{"ABILIFY": 10.15134321552979, "AVANDIA": 11.517689810883622, "BRIDION": 19.796226954076065, "COMIRNATY": 0.1473621400532253, "CUBICIN": 19.176477140611063, "DEXAMETHASONE": 2.742120645304142, "FENTANYL": 10.727587770562671, "GLUCAGON": 87.4524883122731, "KEPPRA": 1.4359309526606598, "MIDAZOLAM": 13.914263125093768, "OLANZAPINE": 3.4253564516524757, "SPIKEVAX": 0.1633308573594054, "ZYPREXA": 3.288391837224776, "null": 2.1342285241050734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6004.json
index 88d8432a2b8..aec88566466 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6004.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6004.json
@@ -1 +1 @@
-{"ADCIRCA": 169.2042777497253, "AZATHIOPRINE": 60.38527609623851}
\ No newline at end of file
+{"null": 7.402773206193315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6005.json
index 4e144bf6cc1..f9038595377 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6005.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6005.json
@@ -1 +1 @@
-{"COMIRNATY": 1.61081277399819, "COVID19": 4.700049216497536, "TOZINAMERAN": 4.350231800153703}
\ No newline at end of file
+{"ARAVA": 0.3948389836669522, "AUBAGIO": 5.027342780426489, "BENLYSTA": 7.131662929342876, "BUDESONIDE": 3.535368505413264, "BYETTA": 12.624110253195848, "CIMZIA": 2.6311859919486573, "COMIRNATY": 0.0988636252979578, "CYMBALTA": 4.822862929638955, "HUMIRA": 2.7958462345681245, "IBRANCE": 3.049835233478537, "JANUMET": 21.339642665241865, "JANUVIA": 16.49436088771977, "JARDIANCE": 1.2627198841122715, "METHOTREXATE": 5.84528516493047, "OPSUMIT": 3.9693415931929272, "RUCONEST": 22.422541020961425, "SIMPONI": 5.388383504592668, "STELARA": 4.660486218927783, "TREMFYA": 6.45624761047756, "XELJANZ": 1.8519301535599857, "ZOSTAVAX": 9.396171342498072, "ZYPREXA": 1.4307792764452116, "null": 1.1862720838374616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6006.json
index 5a5b3758385..b810b2f977d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6006.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6006.json
@@ -1 +1 @@
-{"ASPARAGINASE": 12.29160763943474, "AVAMYS": 49.3208762989773, "BYETTA": 4.594623835629918, "COSENTYX": 2.2880288254742767, "ELIQUIS": 1.5318417632416037, "HUMALOG": 4.3363732384206175, "IBRANCE": 1.2122634439885838, "KEPPRA": 1.007324612767986, "LANTUS": 1.342551185424429, "LYRICA": 2.7245223451990213, "OLANZAPINE": 5.306813913390497, "RINVOQ": 3.681188859816153, "SUBOXONE": 4.170635175804756, "TOVIAZ": 6.977681065854134, "TREMFYA": 6.10867273416731, "XELJANZ": 1.125977319063301, "ZOSTAVAX": 14.152103584257732, "ZYPREXA": 4.157780558618842, "null": 1.382810643849948}
\ No newline at end of file
+{"CIMZIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6007.json
index e58c821c28d..46c2538ccaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6007.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6007.json
@@ -1 +1 @@
-{"COMIRNATY": 11.453165702058676, "SPIKEVAX": 1.736645492156021, "TOZINAMERAN": 2.5818452495589224}
\ No newline at end of file
+{"null": 5.168424431654815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6008.json
index bfaba91e2c6..5f053b13388 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6008.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6008.json
@@ -1 +1 @@
-{"COMIRNATY": 9.183405092974358, "SPIKEVAX": 1.4917827725506114, "TOZINAMERAN": 2.0284966627441463}
\ No newline at end of file
+{"COMIRNATY": 0.7612133588596941, "null": 0.7119897356285397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6009.json
index d46530e9bb0..cbdfc783d2a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6009.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6009.json
@@ -1 +1 @@
-{"COMIRNATY": 9.93563583106262, "SPIKEVAX": 2.47919315784784, "TOZINAMERAN": 2.7015098054646414}
\ No newline at end of file
+{"COMIRNATY": 1.0243219012423574, "SPIKEVAX": 0.4517857500893517, "TOZINAMERAN": 1.5045016821458217, "VAXZEVRIA": 0.4022817152499971, "null": 0.860756694424549}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/601.json
index ceb0007cb39..914a8f975c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/601.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/601.json
@@ -1 +1 @@
-{"ALDARA": 67.13065316459243, "AMELUZ": 527.973245072209, "BETAFERON": 5.275672012420706, "BUPRENORPHINE": 4.786551077400051, "COVID19": 1.3902874216807948, "EVRA": 41.57151758806449, "IMIQUIMOD": 46.70213617853167, "KENTERA": 167.28006146326328, "MIRVASO": 73.8955897172656, "NEULASTA": 1.1806128886659797, "NIMENRIX": 1.7099728281405602, "PLEGRIDY": 1.4497642042599692, "QUTENZA": 225.33352477841436, "ROACTEMRA": 1.1937389042200566, "SHINGRIX": 1.085652013832016, "SPIKEVAX": 1.6330031060847847, "ZYCLARA": 30.13932401420249, "null": 3.1756403525679224}
\ No newline at end of file
+{"ABATACEPT": 0.3052381325137126, "ADALIMUMAB": 0.2405054378885024, "ADCIRCA": 0.5015763803836966, "ADVATE": 1.562611035127755, "AERIUS": 0.5956594163436036, "AFINITOR": 0.1041713686480362, "AIMOVIG": 0.5515461549771644, "ALEMTUZUMAB": 0.1649271703702919, "ALIMTA": 0.6785894744731716, "AMGEVITA": 12.494737353107771, "ANAKINRA": 0.4297709512923622, "APIDRA": 0.4389359608224475, "APIXABAN": 0.3417558322000085, "APREMILAST": 0.21300998871931, "APREPITANT": 0.9644962791118336, "ARANESP": 0.1950768669709156, "ARAVA": 0.885123684373844, "ASPARAGINASE": 1.6663019690341316, "AUBAGIO": 0.1275823877862886, "AVASTIN": 0.7983261605179601, "BENLYSTA": 0.8539807018615323, "BEVACIZUMAB": 0.3228853388496834, "BEXSERO": 1.0383319762950909, "BONVIVA": 0.6007466260149231, "BORTEZOMIB": 0.3292455498149204, "BOTULINUM": 0.9509651002176576, "BRIDION": 48.94939742335712, "BUDESONIDE": 0.611991344150607, "BUPIVACAINE": 1.1906421940677432, "BUPRENORPHINE": 0.1821282971579051, "BYDUREON": 0.5491937843297561, 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0.9190401247924236, "EVUSHELD": 2.8118133993395933, "EXJADE": 0.0872022646263089, "FASENRA": 4.6894748747482735, "FASLODEX": 0.4530434248188033, "FASTURTEC": 5.5744957362280125, "FENTANYL": 8.237293411691851, "FILGRASTIM": 0.7073585735667886, "FLEBOGAMMA": 3.992144229332423, "FLUCELVAX": 1.663326341753678, "FORSTEO": 0.1396244010978336, "GARDASIL": 1.0219411347863077, "GAZYVARO": 1.2598353153726247, "GREPID": 5.3562349269588125, "HERCEPTIN": 1.5030880306434715, "HIZENTRA": 1.4686052265459728, "HUMALOG": 0.3139730293903601, "HUMAN": 3.336911290583924, "HUMIRA": 0.9372580574208716, "HYDROCORTISONE": 0.6936202125823355, "HYQVIA": 1.021077527966076, "IBUPROFEN": 2.090677218960239, "INFANRIX": 0.5906296075137183, "INFLIXIMAB": 0.6465378660181119, "INSULIN": 0.5476855572046259, "IPILIMUMAB": 0.5117443823895595, "IRBESARTAN": 0.552605862529642, "IRON": 0.8317093469067666, "JANUMET": 0.0761596479937713, "JANUVIA": 0.2081662580821973, "JARDIANCE": 0.1286928974038279, "KEPPRA": 0.0527618637044439, "KEYTRUDA": 0.3049866359484718, "KIOVIG": 5.22118317497265, "KUVAN": 4.330653653870778, "KYMRIAH": 0.2475388824345945, "LANTUS": 0.4526188384052677, "LATUDA": 0.315956056910809, "LEFLUNOMIDE": 0.7068470186351316, "LEMTRADA": 0.1672705810721559, "LEVEMIR": 0.6522397360553077, "LEVETIRACETAM": 0.0741827515541501, "LEVOFLOXACIN": 1.8163930223165508, "LIXIANA": 0.2646834824371971, "LYRICA": 0.1759713665255448, "MABTHERA": 0.6601469992420586, "MANNITOL": 2.537572865930953, "MEKINIST": 0.0926228227100773, "MENVEO": 0.5958400568109717, "MEPOLIZUMAB": 0.6711927611958527, "METHOTREXATE": 0.2956913021284968, "MICARDIS": 1.135041198232531, "MIDAZOLAM": 10.712664122511526, "MIRCERA": 3.3934233926249253, "MIXTARD": 1.8125334334774152, "MMRVAXPRO": 0.3995004713804208, "MODERNA": 0.1476913173748718, "NAGLAZYME": 1.0493224333848958, "NEULASTA": 1.890044685889976, "NEXAVAR": 0.0750862207770139, "NIMENRIX": 1.142273974018415, "NOT": 1.2117018696437143, "NOVORAPID": 0.284010563336607, 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0.0763325141736133, "XELODA": 0.4066816250704567, "XOLAIR": 12.053614301991722, "ZOSTAVAX": 0.3129494903161882, "ZYPREXA": 0.1287098065989334, "null": 2.508933216219049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6010.json
index f771f620527..d4b932ec428 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6010.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6010.json
@@ -1 +1 @@
-{"null": 2.182707492679382}
\ No newline at end of file
+{"COMIRNATY": 1.2484128608648415, "null": 1.5246988716777894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6011.json
index 243ab4570b9..8b5194a1f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6011.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6011.json
@@ -1 +1 @@
-{"null": 2.9024745245448345}
\ No newline at end of file
+{"LEMTRADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6012.json
index 815f4731190..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6012.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6012.json
@@ -1 +1 @@
-{"null": 1.3489941582883689}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6013.json
index a72ea3cf907..441da48f8ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6013.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6013.json
@@ -1 +1 @@
-{"OFEV": 26.952328427651786, "OPSUMIT": 91.22856756866656, "TRACLEER": 29.742254816213222}
\ No newline at end of file
+{"COMIRNATY": 1.147782144732601, "TOZINAMERAN": 2.6299751504756195, "null": 0.8606339996356857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6014.json
index 26351a69477..ccc748dcb77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6014.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6014.json
@@ -1 +1 @@
-{"COVID19": 1.5393345123460973, "VAXZEVRIA": 6.246853154745332}
\ No newline at end of file
+{"null": 2.594930830139385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6015.json
index d732a89f6d2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6015.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6015.json
@@ -1 +1 @@
-{"FENTANYL": 3.596827998485142, "KEYTRUDA": 3.268273782571876, "LEVOFLOXACIN": 4.117386491830603, "MEPOLIZUMAB": 4.304199607577753, "MIDAZOLAM": 11.04670330123272, "NUCALA": 3.531892536643995, "OPSUMIT": 6.12531872656195, "SYNAGIS": 11.07455627423752, "TRACLEER": 7.189704036274527, "TRELEGY": 7.57887493788218, "null": 1.058275168824472}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6016.json
index ef1b5cb558f..1e1bd04982e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6016.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6016.json
@@ -1 +1 @@
-{"ACLIDINIUM": 1.2396010552273944, "ADCIRCA": 14.282584438429122, "ADEMPAS": 9.67984937874514, "AMBRISENTAN": 3.533498342552415, "ANORO": 1.687495526839224, "ATOSIBAN": 4.237081668099353, "BAVENCIO": 6.948926063799539, "BENZODIAZEPINE": 1.9606852728960773, "BOSENTAN": 8.379748697437957, "BRIDION": 15.043253080145272, "BRIVARACETAM": 2.0226916491779696, "BUPIVACAINE": 2.3652898150308777, "CAELYX": 1.9666998964878328, "CUBICIN": 1.6777553223523642, "CYTARABINE": 1.0166239073122671, "DARZALEX": 7.820938050190069, "DEXAMETHASONE": 1.5204898700091398, "DEXMEDETOMIDINE": 4.111406849262989, "DUPIXENT": 3.359134245777305, "EMEND": 3.3625196943629496, "ESBRIET": 10.037274736203733, "FASENRA": 3.1457537149250325, "FASTURTEC": 11.494452366391998, "FENTANYL": 6.764085227172628, "FIRDAPSE": 1.1647719357410982, "FLEBOGAMMA": 17.462511487671325, "FYCOMPA": 1.0209416598679864, "GANCICLOVIR": 2.1666263893054003, "GAZYVARO": 4.756680736940636, "GLYCOPYRRONIUM": 4.032460186567593, "HERCEPTIN": 2.0195810231110745, "HIZENTRA": 1.260006524710941, "HUMAN": 1.0763278165462042, "HYDROCORTISONE": 2.0839877497959094, "INCRUSE": 3.496080049811848, "INFANRIX": 3.1822942090515136, "INTEGRILIN": 2.8390676152454493, "JEVTANA": 1.3473462413318056, "KALYDECO": 2.0201211412468534, "KIOVIG": 8.142419989866568, "KYMRIAH": 3.0504200676910527, "LACOSAMIDE": 1.4598893152014203, "LEMTRADA": 1.0577285686096156, "MABTHERA": 1.137149761880062, "MEPOLIZUMAB": 3.1686839029537186, "METHOTREXATE": 1.6788555288553824, "MIDAZOLAM": 10.08318538212028, "NAGLAZYME": 12.78571142085263, "NALOXONE": 12.215405345823244, "NOT": 1.131095883923515, "NUCALA": 3.247376428256293, "OBINUTUZUMAB": 3.634564435890242, "OFEV": 7.071504980995843, "OLANZAPINE": 1.2477719751261622, "OMALIZUMAB": 2.2725482753591963, "ONCASPAR": 5.553547877119749, "OPSUMIT": 10.51309914329442, "ORKAMBI": 1.4038707379291098, "PERJETA": 8.046205184682673, "PIRFENIDONE": 5.823960767821354, "POPPERS": 14.795588577484311, "PREGABALIN": 1.1593198435593264, "PRIVIGEN": 8.897954141189457, "QARZIBA": 3.4826469525089703, "RASBURICASE": 15.4096195532012, "RELVAR": 1.130152513393886, "REMDESIVIR": 5.526829435949915, "REVATIO": 5.742346903072885, "RILUTEK": 4.895565807919141, "RITUXIMAB": 5.994611888015808, "RIVAROXABAN": 2.84112514037655, "RIXATHON": 10.308229891350392, "SILDENAFIL": 5.834543748083668, "SPINRAZA": 5.296742676414011, "SUFENTANIL": 4.890392953782203, "SYNAGIS": 8.98293093621433, "TOBI": 12.154623634098035, "TOCILIZUMAB": 1.3779635535578585, "TORISEL": 2.470699428981729, "TOZINAMERAN": 1.0696051622868783, "TRACLEER": 6.225367342205363, "TRELEGY": 5.1563944749702895, "VEKLURY": 8.443477208431764, "VELTASSA": 1.3080430581970617, "XOLAIR": 1.5558670819135545, "ZYPADHERA": 1.6677613650029477, "null": 1.656104821597777}
\ No newline at end of file
+{"ICLUSIG": 224.17622711282465, "METHOTREXATE": 37.05536417913332, "null": 0.6502256512287952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6017.json
index 0978ae546bf..7fb6fdfdaff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6017.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6017.json
@@ -1 +1 @@
-{"null": 1.1364325208437909}
\ No newline at end of file
+{"ICLUSIG": 216.95484361890703, "null": 0.4175806272323522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6018.json
index 840933eea64..9cf2cbedaea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6018.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6018.json
@@ -1 +1 @@
-{"IRBESARTAN": 128.9482607467275}
\ No newline at end of file
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6019.json
index c66651b6fc2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6019.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6019.json
@@ -1 +1 @@
-{"ANORO": 10.732583349401162, "AVANDIA": 8.30495392094646, "CELLCEPT": 3.78583408742792, "INCRUSE": 63.59037986865131, "KEYTRUDA": 4.168712712046613, "OPSUMIT": 13.125976067632, "TRACLEER": 5.5005768303592655, "TRELEGY": 32.796794120896024, "null": 2.335389151187984}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/602.json
index 3a316ac7d84..be5d412fb56 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/602.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/602.json
@@ -1 +1 @@
-{"AMELUZ": 1032.0127431283329, "null": 16.49450891866841}
\ No newline at end of file
+{"ADALIMUMAB": 0.0152310653813707, "AERIUS": 0.9572206023695272, "AIMOVIG": 0.250894445317829, "ALIMTA": 1.0378390679784324, "APIDRA": 0.1685885310755963, "APROVEL": 0.8646797087038165, "ARAVA": 0.1151733585711184, "ASPARAGINASE": 1.543444709503757, "AVASTIN": 1.8809523072401912, "BENLYSTA": 0.1929712686405147, "BEVACIZUMAB": 0.5461699787041839, "BONVIVA": 1.3697328333756724, "BRIDION": 62.6190984551573, "BRILIQUE": 0.3267886574947992, "BUDESONIDE": 0.6912973312112722, "BUPIVACAINE": 0.3720071648484438, "BYDUREON": 0.3296538049766005, "BYETTA": 0.3471800660607809, "CAELYX": 2.5660765514582184, "CEFUROXIME": 14.998257129528922, "CELLCEPT": 0.0929957836068782, "CHLORHEXIDINE": 2.5377056795273143, "CICLOSPORIN": 0.1502310129403352, "CIMZIA": 0.2625267707538285, "CLOPIDOGREL": 0.181723335525403, "COAPROVEL": 0.4326283539425648, "COMIRNATY": 0.2087075861172886, "COSENTYX": 0.1556205450444829, "CUBICIN": 1.173395950832845, "CYMBALTA": 0.1096954459627212, "CYTARABINE": 0.1940688625228285, "DARZALEX": 1.0023008569383431, "DEXAMETHASONE": 3.603413232380194, "DEXDOR": 11.185645503700629, "DEXMEDETOMIDINE": 2.6236905544891456, "DOCETAXEL": 0.3261061648277295, "ELIQUIS": 0.0542228437960731, "EMEND": 2.1454589944833344, "ENBREL": 0.2079058031286593, "ENTRESTO": 0.1391829800935945, "ENTYVIO": 0.4352169123569152, "ERBITUX": 2.1832359194945603, "FASENRA": 0.4518464030536961, "FASLODEX": 0.4919413243472599, "FASTURTEC": 16.892588066902487, "FENTANYL": 5.617398759622583, "FLEBOGAMMA": 1.3116786745463622, "FORSTEO": 0.0750205393831656, "GARDASIL": 0.3826850774217962, "GAZYVARO": 1.5377202896978035, "GLUCAGON": 2.314713020934067, "HERCEPTIN": 1.10653145668034, "HUMALOG": 0.177545326685655, "HUMAN": 0.7276118465014059, "HYDROCORTISONE": 0.4345707866984414, "IBUPROFEN": 0.6388794764353861, "INSULIN": 0.3930261742855727, "KEPPRA": 0.104839601993566, "KEYTRUDA": 0.2030800700781123, "KIOVIG": 3.8399960865024623, "LANTUS": 0.0846657912354975, "LEVEMIR": 0.2353012959979656, "LEVOFLOXACIN": 2.8600696913968195, "LYRICA": 0.1110892345879517, "MICARDIS": 0.7885820580100587, "MIDAZOLAM": 14.791913494924014, "MIRCERA": 2.231083079273147, "MIXTARD": 2.9126298870710503, "MMRVAXPRO": 0.1345915061487824, "NEULASTA": 0.6999305132784261, "NOT": 1.433254820270035, "NOVORAPID": 0.4564450925733094, "NUCALA": 0.2779098724944724, "OMALIZUMAB": 0.2726092035922288, "ONCASPAR": 8.05132336096863, "OPDIVO": 0.2186544043637709, "PACLITAXEL": 0.5002494273197718, "PANTOPRAZOLE": 0.2561629637361267, "PEGASYS": 0.1298305448695812, "PEGINTRON": 0.1038803661250598, "PERJETA": 5.335533042116636, "PLAVIX": 0.2029087047093707, "PRIVIGEN": 1.0342080949058416, "REMICADE": 0.8664025770560839, "RIXATHON": 1.7050380910068694, "ROACTEMRA": 1.5352736531547353, "SAXENDA": 0.3006648794719569, "SHINGRIX": 0.2204281196304503, "SIMPONI": 0.0997588863629826, "SOLIRIS": 0.1355115750141915, "SPIKEVAX": 0.0944232689496708, "STELARA": 0.3550847087117256, "SUBOXONE": 0.254370982806334, "SUFENTANIL": 109.9967214958737, "SUGAMMADEX": 25.2329362032695, "SYNAGIS": 0.2776142365139996, "TAMIFLU": 1.499253768379376, "TORISEL": 0.6570700346353416, "TOZINAMERAN": 0.3330133021908555, "TRELEGY": 0.2571352665484153, "TRULICITY": 0.1590589463301912, "TWINRIX": 0.6771197827617499, "VAXZEVRIA": 0.0956883590965741, "VFEND": 0.1554350447325805, "VICTOZA": 0.3733055452466594, "XELJANZ": 0.0575453509984582, "XOLAIR": 1.7046836233767333, "ZOSTAVAX": 0.0656908060975103, "null": 6.6182060149589566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6020.json
index 6fafa0347f5..d7e80e1d246 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6020.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6020.json
@@ -1 +1 @@
-{"CELLCEPT": 555.7050803405959}
\ No newline at end of file
+{"null": 2.787377073635478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6021.json
index 6da6e667bec..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6021.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6021.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6022.json
index 9ea338607a1..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6022.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6022.json
@@ -1 +1 @@
-{"null": 2.8697248265443647}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6023.json
index 1c686d8ef19..f9297abccd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6023.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6023.json
@@ -1 +1 @@
-{"FENTANYL": 22.146796648540803, "HYDROCORTISONE": 42.12694531530786, "MIDAZOLAM": 88.88622571793454, "null": 1.844521858586168}
\ No newline at end of file
+{"null": 1.00126318400449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6024.json
index 738281c8d97..a3f975623a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6024.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6024.json
@@ -1 +1 @@
-{"null": 1.756196526127696}
\ No newline at end of file
+{"EVICEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6025.json
index 58d103fc3e9..4eab3bdf196 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6025.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6025.json
@@ -1 +1 @@
-{"ABRAXANE": 384.2762242630757, "AFINITOR": 39.19263695492248, "CAPECITABINE": 125.74100353664238, "EVEROLIMUS": 320.8386037988223, "FULVESTRANT": 127.98164662635736, "RIBOCICLIB": 139.72286085065116}
\ No newline at end of file
+{"COMIRNATY": 0.6886520118771823, "null": 0.7254051087831385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6026.json
index 3977650035c..246ec4f1d35 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6026.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6026.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 4.789511835591069, "FENTANYL": 7.283054513893038, "HYDROCORTISONE": 28.430124957901445, "null": 2.314794342296027}
\ No newline at end of file
+{"null": 0.9500807176259892}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6027.json
index 358da088fee..23d339dd96e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6027.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6027.json
@@ -1 +1 @@
-{"MIDAZOLAM": 67.08828438022006, "null": 1.941725146518624}
\ No newline at end of file
+{"ELIQUIS": 9.392282812973162, "null": 1.174316626625736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6028.json
index 74267341a0b..4f0c4987573 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6028.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6028.json
@@ -1 +1 @@
-{"null": 1.9474346804572036}
\ No newline at end of file
+{"CICLOSPORIN": 5.408607357381165, "COMIRNATY": 0.3445013829465722, "GARDASIL": 4.383536482427187, "KAFTRIO": 20.22836243330241, "SOMATROPIN": 241.6653602346964, "SPIKEVAX": 0.1072145714757335, "STELARA": 2.184290362972145, "TESTOSTERONE": 65.5316144352414, "TOZINAMERAN": 0.7005828715281948, "VAXZEVRIA": 0.0903083203902211, "ZYPREXA": 1.7149927601706536, "null": 2.7024350640693378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6029.json
index 02567f6ca69..071c1c1a06d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6029.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6029.json
@@ -1 +1 @@
-{"null": 2.5460556445726743}
\ No newline at end of file
+{"BROLUCIZUMAB": 2660.372760591177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/603.json
index 67fefe40557..5eca7ace66a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/603.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/603.json
@@ -1 +1 @@
-{"null": 11.135564435826042}
\ No newline at end of file
+{"ADALIMUMAB": 0.1987556532723077, "ALIMTA": 1.1426141472628624, "ASPARAGINASE": 2.073248773058864, "AVASTIN": 5.677572293275682, "BRIDION": 44.795015537124655, "BUDESONIDE": 0.7385126610468821, "CAELYX": 5.894912179903048, "COMIRNATY": 0.2024643744080535, "DARZALEX": 2.5474246826309743, "DEXAMETHASONE": 1.2502895348521874, "FASENRA": 1.3803668422778617, "FASLODEX": 1.3471760764093013, "FENTANYL": 7.427675002465234, "FLEBOGAMMA": 6.163378161538409, "GARDASIL": 0.219068942918392, "HUMALOG": 0.4179123187298104, "HUMAN": 9.032066298486807, "IBUPROFEN": 0.7829547044685705, "ISOPHANE": 19.088555070127462, "KIOVIG": 17.596572886453956, "LANTUS": 0.216378108947878, "LEVOFLOXACIN": 4.339155664456813, "MEPOLIZUMAB": 0.8406484936880793, "MIDAZOLAM": 8.222547265549204, "PEGASYS": 0.20496152639116, "PRIVIGEN": 3.169751808219294, "ROACTEMRA": 2.507135248392041, "SPIKEVAX": 0.132411457276361, "STELARA": 0.8388198308539826, "SUFENTANIL": 19.71177305225272, "TAMIFLU": 3.8301099961695777, "TOZINAMERAN": 0.1375148884996993, "VAXZEVRIA": 0.1457889458670169, "XOLAIR": 3.496956817012715, "null": 5.108203649759658}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6030.json
index 2d66adec518..b28500ad30f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6030.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6030.json
@@ -1 +1 @@
-{"null": 2.2450342229325893}
\ No newline at end of file
+{"BUSULFAN": 163.14901252605057, "CICLOSPORIN": 45.09136339437031, "null": 0.2571802866768885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6031.json
index 44c98391189..563d42f5cf0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6031.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6031.json
@@ -1 +1 @@
-{"ABACAVIR": 2.175452404913429, "ABATACEPT": 1.630032520594547, "ACLASTA": 2.3953645926889715, "ADALIMUMAB": 1.6434268780372303, "AIMOVIG": 1.2114089119571936, "ALDARA": 1.0521709088906166, "ALIGN": 2.930915342815897, "ALL": 1.1283293442409088, "AMBROXOL": 4.720173517702025, "AMELUZ": 2.400725791329203, "AMINOSALICYLIC": 1.5642977781532623, "AMLODIPINE": 3.943724599579484, "ANAKINRA": 3.0632426423754064, "ANALGESICS": 1.175355246355276, "APREMILAST": 1.0242279112528772, "ARAVA": 3.2036804497545424, "ATRIPLA": 4.198385354821227, "AUBAGIO": 1.0850166297804742, "AVAMYS": 1.2634902053253756, "BELIMUMAB": 1.5568230260608955, "BENLYSTA": 1.767532260315, "BEXTRA": 1.28501042147212, "BONVIVA": 1.4634604559503723, "BOTULINUM": 3.704221710221257, "BUDESONIDE": 1.298939975856977, "BUPIVACAINE": 2.5481860456262657, "CABOTEGRAVIR": 2.297679117049065, "CAFFEINE": 2.840861513301707, "CAPSAICIN": 1.006000866060083, "CHLORHEXIDINE": 2.151737425162009, "CIMZIA": 1.8150178841733575, "COMIRNATY": 1.0809370029666987, "COMPRESSION": 3.4695799844341626, "CONTRAST": 1.9080516974780075, "COSENTYX": 1.5887274479407365, "COVID19": 1.5288942955935618, "DACLIZUMAB": 4.513551486942567, "DINUTUXIMAB": 2.0656398630683253, "ELMIRON": 1.098537710126214, "ENBREL": 1.862020012062576, "ERELZI": 2.9132865134718418, "FLUCELVAX": 1.3330639640535131, "FORSTEO": 1.4065617998649496, "GALAFOLD": 1.1962035407274705, "GARDASIL": 1.0422775372960091, "HIZENTRA": 1.036376634398494, "HUMIRA": 1.4452067944023077, "IBRANCE": 1.0984193269890228, "INFERGEN": 1.244257900134654, "KEVZARA": 2.0493777191454114, "LEFLUNOMIDE": 1.5525448904019543, "LEVOFLOXACIN": 1.6272172901214363, "LUPKYNIS": 1.1197846046420346, "LUVERIS": 1.7465133863217936, "LYRICA": 1.8184903271436947, "MENVEO": 1.9430353899206585, "METHOTREXATE": 1.1484536773821057, "NEXOBRID": 17.185945869110345, "NIVESTIM": 1.9236000299051097, "OCRELIZUMAB": 1.6452610677883663, "OCREVUS": 1.17585382319552, "OPTIMARK": 4.629547651816242, "ORENCIA": 1.973713630087941, "PREGABALIN": 1.1792809979624972, "PRIALT": 2.6518190039929026, "QARZIBA": 5.133261962339349, "QUTENZA": 4.2188097595354535, "REKAMBYS": 2.384535265350324, "RINVOQ": 1.1303173349405422, "SHINGRIX": 3.0336105842129872, "SIMPONI": 1.8146573376497503, "SOMAVERT": 1.279345202117344, "SPIKEVAX": 1.221993208838828, "STRIBILD": 4.357759529926079, "SUBOXONE": 1.1288234258964247, "TASIGNA": 1.7104808661407933, "TOZINAMERAN": 2.266764295438391, "TRUVADA": 3.657662426043725, "VAXZEVRIA": 1.696778338404075, "VIREAD": 2.7221747215539653, "XELJANZ": 2.081006176716522, "XIAPEX": 1.6461766804652458, "XOFIGO": 1.919559916191511, "ZARZIO": 2.724640815870433, "ZOSTAVAX": 1.1610196776169042}
\ No newline at end of file
+{"CICLOSPORIN": 1.5342738967740044, "COMIRNATY": 0.0695711314367538, "ESBRIET": 160.12044965908808, "OFEV": 650.3447195237708, "OPSUMIT": 2.910931409694798, "PIRFENIDONE": 166.8642218539805, "null": 0.524728315648665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6032.json
index 64ad83a131a..61ed6df0337 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6032.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6032.json
@@ -1 +1 @@
-{"ACLASTA": 1.1020976752232, "ADEMPAS": 1.298133411668795, "AJOVY": 1.2790021971668282, "ALENDRONATE": 2.606020428429274, "AMGEVITA": 2.3360798188649907, "ANORO": 2.045389340495568, "BEXSERO": 1.645622616948858, "COMIRNATY": 2.5356407742444707, "CONTRAST": 2.026723948657412, "COSENTYX": 1.0162383807326023, "COVID19": 2.674247190492264, "DENOSUMAB": 1.1368351836596895, "DUPIXENT": 1.055975079311425, "ELASOMERAN": 1.0736817236651222, "ENBREL": 1.0551536875474512, "ERELZI": 1.040091586039198, "EVISTA": 1.1987788102935912, "FLUCELVAX": 2.7038708746155344, "FORSTEO": 2.96589565331395, "GARDASIL": 1.317827392321412, "GILENYA": 1.2276429618207112, "HUMIRA": 1.0697994960451704, "LEFLUNOMIDE": 1.3979110111433823, "MENVEO": 1.2162128421534784, "MOVYMIA": 3.482328270930943, "NIMENRIX": 1.8555549510470095, "OCRELIZUMAB": 1.4382905476066845, "OMNITROPE": 1.053348098462452, "OPTIMARK": 1.2257831901282288, "REMSIMA": 1.2140589159413733, "SEMAGLUTIDE": 3.958832904283301, "SHINGRIX": 3.0119131796131686, "SPIKEVAX": 2.219818141371047, "TERIPARATIDE": 1.2715698747050836, "TERROSA": 2.738348488732794, "TOZINAMERAN": 3.0667185005472817, "TWINRIX": 2.071919380784036, "UPTRAVI": 1.3054783245433932, "VAXZEVRIA": 2.8143827402669164, "XELJANZ": 1.370748385981147, "XGEVA": 1.0541363715378802, "XIAPEX": 2.0482966017415256}
\ No newline at end of file
+{"COMIRNATY": 0.38269854266228, "SPIKEVAX": 1.15666635444164, "VAXZEVRIA": 0.5567068817593421, "XOLAIR": 24.82710464781455, "null": 0.7926968853379056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6033.json
index 8d863a027f9..8d1b3ff94d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6033.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6033.json
@@ -1 +1 @@
-{"ADCIRCA": 22.686402456831495, "ADEMPAS": 33.97084848612666, "AFINITOR": 1.042103508371432, "AMBRISENTAN": 20.35193601894708, "AZATHIOPRINE": 1.482701574147834, "BONVIVA": 12.582461971561989, "BRINTELLIX": 1.0773159649585218, "COMIRNATY": 1.2501899306810056, "COVID19": 1.7944200225301712, "CYTARABINE": 1.127302771837804, "ENBREL": 1.2634552757581154, "EVENITY": 3.2613983174053947, "FASLODEX": 1.768901828873552, "FORSTEO": 2.558108499960419, "GARDASIL": 1.1342688711321702, "HUMIRA": 1.602507469300175, "MACITENTAN": 17.636502907876174, "OPSUMIT": 18.829791754004464, "REVATIO": 3.0770392163178446, "SILDENAFIL": 9.434279023778418, "SPIKEVAX": 1.089857893973841, "SUNITINIB": 8.918078838186114, "SUTENT": 1.6182482278685817, "TOZINAMERAN": 2.7480001493909283, "TRACLEER": 4.122891400100203, "UPTRAVI": 36.82329903554431, "ZOMETA": 9.804681688608202}
\ No newline at end of file
+{"null": 3.749609635105247}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6034.json
index 2bb2c374abe..8a070362637 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6034.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6034.json
@@ -1 +1 @@
-{"AIMOVIG": 1.3787400323617198, "APIXABAN": 3.966077238203885, "BENLYSTA": 1.3531865192011665, "COMIRNATY": 1.3664428507668107, "COSENTYX": 2.575693410398263, "COVID19": 3.1204990500754066, "FIASP": 2.567970792699055, "HYDROCORTISONE": 3.547850538933444, "NEXAVAR": 4.649006485479259, "OPTIMARK": 8.872682436509104, "RINVOQ": 2.364682603535332, "SHINGRIX": 7.593015475575824, "SPIKEVAX": 1.8168159525179783, "STIVARGA": 10.981597830924182, "SUTENT": 1.3027711602180947, "TOZINAMERAN": 1.714104220110246, "VAXZEVRIA": 2.1876963627845334, "ZOSTAVAX": 1.3331579642970024}
\ No newline at end of file
+{"ATRIPLA": 0.6273980973446623, "CELLCEPT": 8.187917729945985, "CICLOSPORIN": 4.505775585330823, "COMIRNATY": 0.7451689939197075, "KEYTRUDA": 1.58464270699565, "REMICADE": 23.15832860750893, "SIMPONI": 5.69896011509764, "SPIKEVAX": 1.6494622493127242, "STELARA": 8.177090731937334, "TOZINAMERAN": 2.4068217563636622, "VAXZEVRIA": 0.1745631670459526, "null": 0.523769606080151}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6035.json
index f4b2f11cedd..101a5b66efc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6035.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6035.json
@@ -1 +1 @@
-{"SUBOXONE": 165.49235665667692}
\ No newline at end of file
+{"AVASTIN": 97.11525318232968, "IBUPROFEN": 16.40441571088534, "null": 0.5707768662955027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6036.json
index fa0838de4a0..14b8ef2e4f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6036.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6036.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 53.04212209328095, "null": 3.576373745791844}
\ No newline at end of file
+{"ADALIMUMAB": 4.054204185582731, "CIMZIA": 11.301975106472202, "ENTYVIO": 79.89288888786486, "STELARA": 31.13576830552161, "null": 0.186623183488822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6037.json
index 46763e6e902..1dc553b84f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6037.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6037.json
@@ -1 +1 @@
-{"OLANZAPINE": 25.293361852981807, "VIAGRA": 481.4038272174812}
\ No newline at end of file
+{"ABACAVIR": 9.03149706490749, "null": 1.7008560709293985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6038.json
index da2e314bb12..255c66aa8d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6038.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6038.json
@@ -1 +1 @@
-{"BENLYSTA": 2.9166157572853675, "COMIRNATY": 3.026459956159598, "ESBRIET": 3.9207854413148793, "SPIKEVAX": 2.29159335936884, "TAMIFLU": 2.9870078531201028, "TOZINAMERAN": 3.160612064944142, "VAXZEVRIA": 1.0776881877013986, "XELJANZ": 1.2226367161654397}
\ No newline at end of file
+{"AZATHIOPRINE": 127.6242699158896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6039.json
index 3341a2290ff..da1fcded91f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6039.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6039.json
@@ -1 +1 @@
-{"null": 1.8329749510898308}
\ No newline at end of file
+{"AVASTIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/604.json
index 664280acb2c..8480a8b7795 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/604.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/604.json
@@ -1 +1 @@
-{"null": 4.010584589699205}
\ No newline at end of file
+{"BRIDION": 36.33737764168267, "DEXAMETHASONE": 10.871905814482997, "FENTANYL": 3.825028334502896, "MIDAZOLAM": 26.21410166040369, "SUFENTANIL": 212.05232038263395, "null": 5.726427609048711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6040.json
index abc706e40a5..18d0b7b7657 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6040.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6040.json
@@ -1 +1 @@
-{"FENTANYL": 2.317367865057454, "LEVOFLOXACIN": 2.939626795196689, "null": 4.290335942789303}
\ No newline at end of file
+{"CIMZIA": 10.6820679586089, "ENTYVIO": 14.746322769760216, "HUMIRA": 15.434281493634153, "RINVOQ": 44.419145394754246, "STELARA": 16.978702454592298, "XELJANZ": 7.213463462600584, "null": 0.7354939463663731}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6041.json
index efb1519bac7..fceb7965a77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6041.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6041.json
@@ -1 +1 @@
-{"COMIRNATY": 1.646917480822812, "null": 1.2724602151720033}
\ No newline at end of file
+{"ABILIFY": 1.1211287780066357, "AFINITOR": 1.807580044947672, "AIMOVIG": 2.214148738612658, "ALIMTA": 2.156734372783618, "ARAVA": 0.0976582716460927, "ARIPIPRAZOLE": 1.9800297979938424, "ASPARAGINASE": 4.122709627905447, "AVASTIN": 10.791549952735384, "BEVACIZUMAB": 6.402551954055832, "BRAFTOVI": 5.136208007165405, "BYETTA": 2.82373570948684, "CABOMETYX": 2.12947533215046, "CAPECITABINE": 2.1853575552277937, "CELLCEPT": 3.600805118647548, "CHAMPIX": 2.1735371155199514, "CICLOSPORIN": 0.7265295315122753, "COMIRNATY": 0.0553541895883705, "COMTAN": 5.105548748995882, "CRIZOTINIB": 43.906279563289374, "CYMBALTA": 0.4974941000703324, "CYTARABINE": 2.274358284995789, "DEXAMETHASONE": 1.4089728847895282, "ELIQUIS": 0.512251730174891, "EMTRIVA": 27.70636651902821, "ENTYVIO": 1.2935675446703083, "EXJADE": 0.7711529003127429, "FENTANYL": 2.4570957735345043, "GLUCAGON": 40.15298729404237, "HYCAMTIN": 10.828623647493885, "IBUPROFEN": 1.1129551838519676, "INLYTA": 1.2532088288440602, "INSULIN": 1.1681718670866386, "IRESSA": 4.679579289264152, "JAKAVI": 1.0830232553164236, "JANUMET": 1.522541619767179, "JANUVIA": 4.968120112268087, "JEVTANA": 9.83694704904808, "KALETRA": 1.348855521281234, "KEPPRA": 1.688067926000315, "KEYTRUDA": 3.391501897468668, "LACOSAMIDE": 2.825157680906482, "LYNPARZA": 14.333372117004169, "LYRICA": 1.3230532945190607, "MIDAZOLAM": 1.9091204506942685, "NEXAVAR": 0.4742410509234097, "NOXAFIL": 4.532827050205031, "OLANZAPINE": 1.9548369690940255, "OPDIVO": 1.8322900459478892, "PEGINTRON": 0.6179994278935713, "PLAVIX": 0.4896482012144579, "REMICADE": 3.4049528078020925, "ROTATEQ": 3.563286202626382, "SAXENDA": 1.7500581851225605, "SPIKEVAX": 0.0572020826285073, "STALEVO": 6.712852956988915, "STELARA": 1.4355685416861246, "STIVARGA": 5.109396343139419, "SUTENT": 0.7075414982370715, "TAMIFLU": 1.9841066805506535, "TOVIAZ": 3.5806682207386484, "TRULICITY": 3.914229888618311, "VFEND": 1.9337936582833488, "VICTOZA": 2.059758247138987, "XELODA": 5.047902978645126, "XTANDI": 0.91732102041836, "ZYPREXA": 2.752931906856737, "null": 1.7476663071377032}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6042.json
index 8b0ac019ea6..7f79fc81b9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6042.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6042.json
@@ -1 +1 @@
-{"ENBREL": 30.61823952005552}
\ No newline at end of file
+{"AIMOVIG": 2.67517833300743, "ASPARAGINASE": 9.51751603334407, "BORTEZOMIB": 8.055542746336965, "CELLCEPT": 2.515153678683074, "COMIRNATY": 0.0712955081310028, "DEXAMETHASONE": 2.3473163265368338, "DOCETAXEL": 6.386699811510123, "FENTANYL": 1.8200313049218804, "KALETRA": 5.422687216840202, "KEPPRA": 2.812877829746246, "KEYTRUDA": 1.2666786198750717, "METHOTREXATE": 1.6321325728900196, "MIDAZOLAM": 7.675210561959552, "NOXAFIL": 11.322323292353287, "OLANZAPINE": 8.154781512363943, "POSACONAZOLE": 19.061689494692185, "SUTENT": 0.4071810804998264, "VICTOZA": 2.9549924825360705, "ZYPREXA": 4.308669342203076, "null": 2.8150046184529933}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6043.json
index 1e87ce0e287..6221529bc1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6043.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6043.json
@@ -1 +1 @@
-{"KEYTRUDA": 6.598997586342115, "OPSUMIT": 12.555415669859109, "VOTRIENT": 25.405691378746152, "null": 1.0106288127795615}
\ No newline at end of file
+{"null": 1.2741546040657432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6044.json
index 0cd1c13c1d4..3ede6d5a877 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6044.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6044.json
@@ -1 +1 @@
-{"AERIUS": 1.395436274903277, "AMIKACIN": 1.0279571259602216, "BEXSERO": 14.245331492820604, "BUPIVACAINE": 1.2558559834406473, "CANNABIDIOL": 3.392398640244805, "CASPOFUNGIN": 3.7841059764973184, "CERVARIX": 6.8690288750390645, "CLOPIDOGREL": 2.539166176506703, "COAPROVEL": 1.0916354400108026, "COMBIVIR": 2.710531658381941, "CYTARABINE": 1.337890433595748, "DIPHTHERIA": 89.76635320086456, "EFAVIRENZ": 1.1601297068334315, "ENOXAPARIN": 1.9266808342016877, "FLEBOGAMMA": 6.844024464594878, "GARDASIL": 9.188264992769335, "HEXYON": 13.751735599676266, "HUMAN": 1.1092075979720537, "INFANRIX": 16.2490572949061, "IRON": 2.503343024660426, "ISCOVER": 4.493169715650098, "JAKAVI": 1.0540281105936986, "KIOVIG": 3.765455318282479, "LAMIVUDINE": 2.7113708571224624, "LANTUS": 1.0828516263804933, "MENVEO": 10.726832060595894, "MERCAPTOPURINE": 2.6016607346539904, "MIXTARD": 3.961992413953552, "MMRVAXPRO": 5.93730885954629, "NAGLAZYME": 7.545442536452517, "NIMENRIX": 8.1210327561741, "NOT": 3.717125591331736, "ONCASPAR": 4.678060512202109, "PEGINTERFERON": 1.0507354548519638, "PREGABALIN": 2.030004192953974, "PREVENAR": 15.129014270833386, "PRIVIGEN": 2.6533243868124803, "RENVELA": 55.62891914932019, "ROTARIX": 31.68844573933464, "ROTATEQ": 10.1835103315336, "SUTENT": 1.1589062056470252, "SYNAGIS": 5.311780570315658, "TAMIFLU": 1.0582521054876384, "TICAGRELOR": 1.6779453030900493, "TOZINAMERAN": 1.432197617531218, "TWINRIX": 4.488031905023656, "XOLAIR": 1.04386650359081, "ZYPADHERA": 4.008174543568239, "null": 1.5660281533863143}
\ No newline at end of file
+{"null": 0.8127770663330414}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6045.json
index edb8465383d..8b3efc5c79b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6045.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6045.json
@@ -1 +1 @@
-{"MANNITOL": 133.11433221108734, "NEXAVAR": 8.540918636972627, "SUTENT": 4.192009470704741, "null": 2.001855876464097}
\ No newline at end of file
+{"null": 0.2298666994433706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6046.json
index c265ea7f5b9..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6046.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6046.json
@@ -1 +1 @@
-{"ABRAXANE": 3.692960490420063, "AFINITOR": 2.9568123020456776, "ALOXI": 13.355275236298018, "AVASTIN": 8.293684266110146, "AVELUMAB": 4.649060618661651, "AXITINIB": 21.53643371209697, "BAVENCIO": 24.120606528277506, "BEVACIZUMAB": 8.156149730935889, "BRAFTOVI": 2.154090941186156, "BUSULFAN": 1.4220660728766887, "CABOMETYX": 62.66580624189505, "CABOZANTINIB": 27.602612950673223, "CAELYX": 58.44418964901055, "CAPECITABINE": 18.791413504171032, "CETUXIMAB": 3.2096717802750594, "CLOFARABINE": 9.674008355036984, "COTELLIC": 1.2232503797355063, "DOCETAXEL": 4.53870810103801, "DOXORUBICIN": 1.968713595412756, "ERBITUX": 4.934282183697775, "ERLOTINIB": 13.580746876506206, "EVEROLIMUS": 7.692662760600868, "FOTIVDA": 21.99549428320448, "HALAVEN": 2.6372436357367146, "HERCEPTIN": 2.8090431608328625, "IBRANCE": 1.0197948048225511, "IMATINIB": 2.707908004736528, "INLYTA": 12.875761466754383, "IRINOTECAN": 1.6155526013914996, "KEYTRUDA": 8.739637151379464, "KISQALI": 1.8486866024223572, "LENVATINIB": 21.372306069844967, "LENVIMA": 31.71208721746813, "LONSURF": 2.95466344205187, "MEKINIST": 1.0741608157682, "NEULASTA": 1.4187106408429562, "NEXAVAR": 119.08039126054707, "PANITUMUMAB": 5.486448857272092, "PAZOPANIB": 16.5570235431447, "PEMBROLIZUMAB": 2.6386768565817307, "REGORAFENIB": 87.94473375117687, "SORAFENIB": 71.92652538146406, "STIVARGA": 108.34766489515604, "SUNITINIB": 21.856100254812542, "SUTENT": 24.47753708966814, "TAGRISSO": 1.7822290237056857, "TAXOTERE": 4.153081478533539, "VECTIBIX": 3.613964997254565, "VOTRIENT": 6.7670847852677065, "XELODA": 21.2059160599237, "ZELBORAF": 5.183406312968176}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6047.json
index 4f56aa5e9b8..09625d32d70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6047.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6047.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.9661001895758865, "APIXABAN": 89.21134541175363, "NEXAVAR": 44.17969983410938, "STIVARGA": 19.616636582000588, "SUTENT": 1.940669764776632, "TAFINLAR": 337.1039155598279, "ZELBORAF": 167.49371806436864}
\ No newline at end of file
+{"null": 1.5345798162876387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6048.json
index 00de127abb9..ace0291cabf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6048.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6048.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.3680156604782103, "BUPRENORPHINE": 16.099570661677454, "CIMZIA": 17.161376005049508, "COSENTYX": 37.98178771646722, "SIMPONI": 43.74717196032708, "STELARA": 12.212346205089586}
\ No newline at end of file
+{"JARDIANCE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6049.json
index 16b0350abf7..1b0f6f1887b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6049.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6049.json
@@ -1 +1 @@
-{"null": 1.5830984175777678}
\ No newline at end of file
+{"null": 0.5846345910800499}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/605.json
index fd07730f558..07b7eee45cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/605.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/605.json
@@ -1 +1 @@
-{"COVID19": 1.2343896278698363, "VAXZEVRIA": 2.025762746033165, "null": 1.0992718788332965}
\ No newline at end of file
+{"null": 2.776536066930761}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6050.json
index 4843f200f97..12770787145 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6050.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6050.json
@@ -1 +1 @@
-{"ADCIRCA": 1.976655259086008, "ADEMPAS": 1.4966295459257504, "AERIUS": 1.710579476492842, "AIMOVIG": 1.219429589545215, "AMBRISENTAN": 1.77936432391901, "ANTIHYPERTENSIVES": 3.6073794538208888, "BEDAQUILINE": 1.1983782605553033, "BETMIGA": 5.7441885439448175, "BRINTELLIX": 1.1800521156028103, "CHAMPIX": 1.7946463300071136, "CIRCADIN": 2.4883188312117897, "COMIRNATY": 2.43251858542271, "COMPRESSION": 9.941292060448715, "COVID19": 1.6643980061169312, "DELAMANID": 1.3352582153280566, "DESLORATADINE": 2.125269300558198, "DUORESP": 2.491452297440771, "EDURANT": 1.124787547059612, "EXFORGE": 1.3526215255835885, "FAMPYRA": 1.9155608041669636, "FEBUXOSTAT": 1.042733688950717, "FORSTEO": 1.721429009384483, "GARDASIL": 1.2780886029557783, "GONALF": 1.1556527720079195, "INSULIN": 1.4261734256858698, "IVABRADINE": 1.8548084541608785, "KARVEA": 1.3496610810503984, "KARVEZIDE": 1.843735592963177, "LEMTRADA": 1.1111432642088108, "MACITENTAN": 1.0282432539939337, "MELATONIN": 1.473246792925045, "MICARDIS": 1.3253206049154782, "MIRABEGRON": 4.400537275479096, "MOVYMIA": 2.849534765575867, "MULTAQ": 1.5606174396289867, "OPSUMIT": 1.145831592066258, "PREOTACT": 3.195143846090982, "PROPRANOLOL": 1.0906832378422993, "RASILEZ": 1.1662563229454777, "RELVAR": 4.144310787372008, "SILDENAFIL": 1.114334402996429, "SPIKEVAX": 1.7592380141887365, "TEKTURNA": 2.2555678102262497, "TELMISARTAN": 1.3312560766207606, "TERIPARATIDE": 1.1534715073620196, "TERROSA": 3.018722676984012, "TICAGRELOR": 1.705338039634564, "TOZINAMERAN": 2.564994031952629, "UROREC": 1.622247685754756, "VALSARTAN": 1.681288579570032, "VAXZEVRIA": 1.145315795020447, "WAKIX": 1.9159168838586456, "ZEJULA": 1.4282665201634277}
\ No newline at end of file
+{"ABACAVIR": 0.2721491830346205, "ABATACEPT": 11.719058409573616, "ACETAMINOPHEN": 32.997923253061934, "ACLIDINIUM": 3.8833784063394505, "ADALIMUMAB": 9.970788545583048, "AFINITOR": 0.3033403598832633, "AIMOVIG": 0.4738515502878125, "AMBRISENTAN": 3.788780259867505, "AMINOSALICYLIC": 0.4494494733148115, "ANAKINRA": 20.493755369896384, "ANORO": 3.007246428613916, "APIDRA": 0.3502810900017465, "APREPITANT": 36.56523764826924, "ARANESP": 0.3196346233548776, "ARAVA": 5.669298790650416, "ATRIPLA": 0.093079240829901, "AUBAGIO": 0.3445571897725001, "AVAMYS": 0.4218385179981685, "AVANDIA": 1.3907103078374663, "AVASTIN": 0.660818880547809, "BENLYSTA": 5.910832044256317, "BENRALIZUMAB": 16.595726808467234, "BIKTARVY": 1.8583172510224728, "BUDESONIDE": 4.193437401191037, "BYDUREON": 0.3568175803146555, "BYETTA": 0.3717069262949521, "CAPECITABINE": 0.7152828552555535, "CARMUSTINE": 4.719764665112564, "CELLCEPT": 1.0862630574498104, "CHAMPIX": 0.5288425981720541, "CHLORHEXIDINE": 47.555122045737264, "CICLOSPORIN": 0.2824983483145852, "CIMZIA": 15.220620153338212, "CLOPIDOGREL": 0.1330279816658433, "COMBIVIR": 1.2286709488347836, "COMIRNATY": 0.0252253493227287, "COSENTYX": 0.4135635522829396, "COTELLIC": 1.6732273065275078, "CYMBALTA": 0.3163952315095519, "CYTARABINE": 1.7713931593990209, "DEXAMETHASONE": 0.8120070454718398, "DOCETAXEL": 0.4509277922012869, "DOXORUBICIN": 1.114112952625498, "ELIQUIS": 0.0726377334460889, "ENBREL": 1.2396597493887451, "ENTRESTO": 0.6188284314374772, "ESBRIET": 2.5033083173049677, "ETANERCEPT": 4.093609534052771, "EVENITY": 6.089371274751175, "FASENRA": 1.309424177739368, "FILGRASTIM": 4.718735223307243, "FORSTEO": 0.2402484242714739, "GARDASIL": 1.1458469352461722, "GAZYVARO": 2.460101203810525, "HARVONI": 0.83056904148773, "HERCEPTIN": 2.488874156373861, "HIZENTRA": 3.575817535833825, "HUMALOG": 0.1350936581080132, "HUMIRA": 0.4083938688263164, "ICLUSIG": 1.3643277081921985, "INCRUSE": 5.66829416162152, "INFLIXIMAB": 1.28401202541026, "INTRONA": 1.887244360803762, "ISENTRESS": 1.755628037407413, "JAKAVI": 0.2914084694361109, "JANUMET": 1.2625608940464077, "JANUVIA": 1.007583645891478, "JARDIANCE": 0.93986806549487, "KEPPRA": 0.9032615266912486, "KEYTRUDA": 1.9504135134032212, "LANTUS": 0.6640822444830988, "LEFLUNOMIDE": 2.49793075857242, "LEVEMIR": 0.9387986107209346, "LEVOFLOXACIN": 0.3311430199246292, "LUTATHERA": 70.3279944907816, "LYRICA": 0.5877477556689704, "MEKINIST": 0.7420216774528527, "MEPOLIZUMAB": 2.538296634904736, "METHOTREXATE": 1.298427013542933, "MYCOPHENOLATE": 0.7607948194659533, "NOT": 0.7632282860832528, "NUCALA": 2.1134315188815878, "OMALIZUMAB": 0.8660314990990573, "ORKAMBI": 1.3265083292261393, "PEGASYS": 1.0779076413394844, "PEMBROLIZUMAB": 1.4809995685339157, "PLAVIX": 0.4379100761988153, "PLUVICTO": 167.9114742317682, "PRIVIGEN": 0.7993836085262631, "RELVAR": 2.138050591156522, "RITUXIMAB": 4.559086718709007, "ROACTEMRA": 3.584760940873281, "SAXENDA": 0.8917494758705996, "SIMPONI": 0.1886982520958265, "SOLIRIS": 1.4267332787376683, "SPIKEVAX": 0.0269688633189344, "STELARA": 0.1356027985348092, "SUBOXONE": 0.1766840171349197, "SUTENT": 0.0615706667821088, "SYNAGIS": 3.151826655051102, "TAGRISSO": 0.5132489095498067, "TAMIFLU": 1.00819652886819, "TOZINAMERAN": 0.0175496326910882, "TRELEGY": 3.4426616104718577, "TRIUMEQ": 2.4291469746753998, "TRUVADA": 0.0530289600088949, "VAXZEVRIA": 0.0538395380098834, "VELTASSA": 2.848164425155161, "VOTRIENT": 2.2008259465544318, "XOLAIR": 0.9263194071268628, "XTANDI": 0.3374566185383595, "ZIAGEN": 4.426544322570443, "ZOSTAVAX": 6.343119266280783, "null": 0.8607985079475635}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6051.json
index 2077bbbf068..47c191829e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6051.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6051.json
@@ -1 +1 @@
-{"DESLORATADINE": 4182.342890189411}
\ No newline at end of file
+{"COMIRNATY": 0.5537709935360621, "null": 2.1386415700192587}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6052.json
index 68ca32eee18..56eb1cb300f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6052.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6052.json
@@ -1 +1 @@
-{"BEDAQUILINE": 661.4397568393958}
\ No newline at end of file
+{"ABASAGLAR": 0.5509388147241265, "ABATACEPT": 0.0816273055348452, "ABILIFY": 0.6704480564412181, "ADALIMUMAB": 0.0355523652440071, "ADCIRCA": 1.20130689687631, "ADEMPAS": 1.3360295664002242, "AFINITOR": 0.8628862593392658, "AIMOVIG": 0.5326255547113277, "ALEMTUZUMAB": 0.2435482905820255, "ALIMTA": 0.2874810366346658, "AMBRISENTAN": 2.336109502701676, "ANORO": 0.7355587645332152, "APIDRA": 1.2356717653166611, "APROVEL": 0.6587528868272801, "ARANESP": 0.4604125788277243, "ARAVA": 0.1762790959975484, "ARIPIPRAZOLE": 0.093324810608258, "ATRIPLA": 0.1044082766823792, "AUBAGIO": 1.2585639708291394, "AVANDIA": 0.1530949577071112, "AVASTIN": 0.1569336764884802, "AVONEX": 2.0280015331854004, "AYESURBY": 63.51362596336912, "AZATHIOPRINE": 0.594182808845584, "BENLYSTA": 4.429623282811039, "BENRALIZUMAB": 0.9239760227143706, "BETAFERON": 0.3433771025037353, "BETMIGA": 0.6040747056528818, "BIKTARVY": 0.2131025388271877, "BOSULIF": 5.318224218804581, "BRAFTOVI": 2.985956947198102, "BRINTELLIX": 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1.3474791127338883, "PREVENAR": 0.7519151470439827, "PRIVIGEN": 0.3160060223605188, "RAPAMUNE": 3.259638513734751, "RASILEZ": 0.4218667626671682, "RELVAR": 0.5429020106330037, "REMICADE": 0.816185826294772, "REVATIO": 5.812672608819377, "REVLIMID": 0.6410048765755999, "RINVOQ": 1.0903872083229, "RISPERIDONE": 0.5016113416373318, "RITUXIMAB": 0.2660641981266589, "ROACTEMRA": 0.2756526678464088, "RUBRACA": 2.1399406483950565, "RUCONEST": 2.6508149923534488, "RYBELSUS": 1.0172028860586046, "SAXENDA": 2.102160483761197, "SHINGRIX": 1.726534376539148, "SILDENAFIL": 0.4562974357779084, "SIMPONI": 2.1405667606073657, "SKYRIZI": 1.1661372651208122, "SOLIRIS": 1.0661845776370191, "SOVALDI": 0.3414730326495309, "SPIKEVAX": 0.8039465918567384, "SPINRAZA": 1.387477718336192, "SPIRONOLACTONE": 0.7805802001750851, "SPRYCEL": 0.4637716184116334, "STELARA": 1.376764952734752, "SUBOXONE": 2.016725912078749, "SUTENT": 1.8550681276167007, "SYNAGIS": 3.071927764491293, "TAGRISSO": 0.2029309691643865, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6053.json
index cd411a2bae7..3954d241e67 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6053.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6053.json
@@ -1 +1 @@
-{"BYETTA": 134.9346561572111, "JANUMET": 103.41019534321238, "JANUVIA": 99.443323290227, "LANTUS": 4.743943228297531}
\ No newline at end of file
+{"null": 1.8696691199934907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6054.json
index 10d1d61aeb2..cf860035071 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6054.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6054.json
@@ -1 +1 @@
-{"HUMALOG": 17.145873204941108}
\ No newline at end of file
+{"null": 1.1765281003619523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6055.json
index 662ae2dad40..36edc2d9c39 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6055.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6055.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.1075353199285973, "ABRAXANE": 3.9089567940666585, "ACTOS": 3.04327444927231, "AMINOSALICYLIC": 1.1319035020460684, "BYDUREON": 16.353532438122055, "BYETTA": 145.43536473368553, "COAPROVEL": 4.1424290065537965, "ELIQUIS": 1.0725837533119855, "EUCREAS": 25.51502488151719, "EXFORGE": 1.095663100537594, "FORXIGA": 1.2675241350325983, "GALVUS": 4.494502709009152, "HUMALOG": 1.6833720172738784, "INSULIN": 1.4081639823131769, "IRINOTECAN": 2.11987767332525, "JAKAVI": 1.1881932420355763, "JANUMET": 51.440316858249815, "JANUVIA": 65.45542945970087, "JARDIANCE": 2.0858960275960685, "LANTUS": 2.2067507224613934, "LEVEMIR": 2.6328489590195447, "METFORMIN": 4.979488155907248, "ONGLYZA": 10.470210013694052, "RINVOQ": 1.050326502214293, "RYBELSUS": 3.893633522379389, "SAXENDA": 2.896273958730941, "SIMPONI": 1.0489594541877192, "TRESIBA": 3.7379279644261154, "TRULICITY": 8.24885553272093, "VELMETIA": 8.513084692751528, "VICTOZA": 40.69340676233741, "null": 1.2623708098431148}
\ No newline at end of file
+{"CHAMPIX": 3.2991472309901693, "COMIRNATY": 0.8499510814300063, "CYMBALTA": 1.2261077664271052, "GARDASIL": 4.387385125561347, "KEPPRA": 1.6867090577250667, "OLANZAPINE": 2.855430598795272, "SPIKEVAX": 0.6125446491557492, "TAMIFLU": 4.0243510242320815, "VAXZEVRIA": 0.3307270170800379, "VFEND": 9.487251932704591, "ZYPREXA": 2.438440532483894, "null": 1.906558227562862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6056.json
index 48c3c1f92bf..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6056.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6056.json
@@ -1 +1 @@
-{"ABRAXANE": 22.55899605603173, "APIDRA": 2.781309411080744, "BRILIQUE": 4.064899658670651, "BYDUREON": 29.75688608270224, "BYETTA": 218.8257052472164, "ENBREL": 1.0928969540483868, "EUCREAS": 13.566853639311631, "IRINOTECAN": 17.032738931035393, "JANUMET": 110.41004211417928, "JANUVIA": 93.2899845189841, "SAXENDA": 2.9478176547389245, "SOLIRIS": 1.7647554965797638, "STELARA": 1.9010589051177165, "TRULICITY": 7.679010726588554, "VICTOZA": 55.47004813841591}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6057.json
index cafc09797bf..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6057.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6057.json
@@ -1 +1 @@
-{"BYETTA": 108.53505549207446, "IRINOTECAN": 178.4899887026813}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6058.json
index aaff66a993c..da1fcded91f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6058.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6058.json
@@ -1 +1 @@
-{"MICARDIS": 212.43699148382075}
\ No newline at end of file
+{"AVASTIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6059.json
index a220e8f03bd..cf860035071 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6059.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6059.json
@@ -1 +1 @@
-{"BYETTA": 87.85846710344173, "JANUMET": 48.44641928719288, "JANUVIA": 26.179956446116638, "VICTOZA": 91.22781600419644}
\ No newline at end of file
+{"null": 1.1765281003619523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/606.json
index 4dfdba2d565..1cedb71802f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/606.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/606.json
@@ -1 +1 @@
-{"ALDARA": 194.16432212653245, "AMELUZ": 428.25188660894895, "BUPRENORPHINE": 9.492685819225697, "LANTUS": 2.942740076789228, "NEULASTA": 147.94494347623447, "SIMPONI": 11.48800511085608, "null": 2.011579604917944}
\ No newline at end of file
+{"CICLOSPORIN": 24.363637936417607, "null": 0.406441001957477}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6060.json
index ace9e0df440..989e30ff485 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6060.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6060.json
@@ -1 +1 @@
-{"BYDUREON": 10.7856489927379, "BYETTA": 37.945158051264414, "JANUMET": 25.0953126842088, "JANUVIA": 25.0127214099448, "SAXENDA": 13.737458709428653, "TRULICITY": 8.842036352729702, "VICTOZA": 13.266886028079169}
\ No newline at end of file
+{"GARDASIL": 62.68624457740534, "SPIKEVAX": 10.121738155634183, "ZYPADHERA": 113.16399785885174, "null": 0.235174800212001}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6061.json
index 4f607f809be..2057f6f84f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6061.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6061.json
@@ -1 +1 @@
-{"APIDRA": 7.440167161696918, "BYDUREON": 7.058984747317663, "BYETTA": 6.109646030140581, "CICLOSPORIN": 1.0447057029543554, "HUMALOG": 11.37197562329227, "INSULIN": 2.60432142302513, "JANUMET": 5.690017729910943, "JANUVIA": 7.704838901039387, "KEYTRUDA": 1.6484476442779143, "LANTUS": 8.725620980853542, "PEGASYS": 1.0719464148645936, "PEGINTRON": 2.273628560753431, "SAXENDA": 7.133313633904936, "SUTENT": 1.080941729275399, "TRULICITY": 13.075804190613146, "VICTOZA": 14.422045817461632, "XELJANZ": 2.159102279470577, "ZYPREXA": 2.9054042186608093}
\ No newline at end of file
+{"null": 0.7934161955149596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6062.json
index 0d3d7d53403..87a853c089b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6062.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6062.json
@@ -1 +1 @@
-{"BYETTA": 81.44228212874353, "JANUMET": 71.3415470343592, "JANUVIA": 21.877513668252533}
\ No newline at end of file
+{"AMINOSALICYLIC": 4.614953050810559, "ARAVA": 4.210660357944211, "ATRIPLA": 0.7275862727154181, "COMIRNATY": 0.4334745761187022, "COMTAN": 14.23706885878834, "ELIQUIS": 1.680889838572783, "ENBREL": 4.820566533687059, "LANTUS": 0.7664999332878694, "OLANZAPINE": 2.451054037225735, "OPTIMARK": 3.136138345715496, "SHINGRIX": 4.70620578673606, "SIMPONI": 1.578244843302041, "SPIKEVAX": 0.4275891717530236, "STELARA": 1.392366839324231, "SUTENT": 0.5704399857153323, "TOZINAMERAN": 1.226894443602167, "VAXZEVRIA": 0.4812803439807024, "XELJANZ": 1.0000449434809002, "null": 1.0876489066371666}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6063.json
index 21ac89825dd..4c792444860 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6063.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6063.json
@@ -1 +1 @@
-{"BYETTA": 67.92853781353745}
\ No newline at end of file
+{"COMIRNATY": 0.3480673454152106, "null": 1.0238351796550105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6064.json
index 7da0857eab1..ab9942bdc32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6064.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6064.json
@@ -1 +1 @@
-{"null": 1.19653130101283}
\ No newline at end of file
+{"YESCARTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6065.json
index 5ba2b4d86dc..4d6db177076 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6065.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6065.json
@@ -1 +1 @@
-{"null": 1.0489532232822167}
\ No newline at end of file
+{"AXICABTAGENE": 701.3511367824474, "BREYANZI": 497.375138176136, "CYTARABINE": 5.067830109690039, "DOXORUBICIN": 11.979266060860573, "EPCORITAMAB": 150.5355155179341, "KYMRIAH": 442.8114166519695, "NIVOLUMAB": 29.17319603670109, "TISAGENLECLEUCEL": 378.3965970313274, "YESCARTA": 2252.4733315214685, "null": 0.0317144999602935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6066.json
index 6ec77f3f747..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6066.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6066.json
@@ -1 +1 @@
-{"BENLYSTA": 6.597701511130713, "BYETTA": 5.567986881249192, "ICLUSIG": 13.177115422234298, "IPILIMUMAB": 10.572297065075528, "JANUMET": 9.064673798950643, "JANUVIA": 8.147849380561984, "KEYTRUDA": 2.742036346706606, "NEXAVAR": 16.551433861855426, "OPDIVO": 7.751427497641741, "PEGASYS": 1.9237127841152817, "SUTENT": 1.257128574708288, "TASIGNA": 8.129112609753763, "TRULICITY": 5.944964742295338, "VICTOZA": 11.323564113713998, "null": 1.113283639725348}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6067.json
index badd79531ad..bf38cb86e9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6067.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6067.json
@@ -1 +1 @@
-{"BYETTA": 18.18703435115625, "COMBIVIR": 56.3254648398669, "HUMALOG": 7.267595990314433, "JANUMET": 6.701352793843782, "KEYTRUDA": 3.436255674831981, "LANTUS": 2.8195342904801777, "TRULICITY": 13.605000342563953}
\ No newline at end of file
+{"ABACAVIR": 17.352714529019355, "ALEMTUZUMAB": 4.145244336690006, "AMIKACIN": 6.272124571394586, "AMINOSALICYLIC": 1.339829089232953, "ASPARAGINASE": 2.080511778153732, "ATAZANAVIR": 51.894146825582986, "ATRIPLA": 2.084981101782758, "BIKTARVY": 62.17207505972675, "BUSULFAN": 1.6218874920394128, "CELSENTRI": 39.17421059660683, "CICLOSPORIN": 0.7923787539961948, "COBICISTAT": 188.4828077047642, "COMBIVIR": 12.806362652213348, "CRIXIVAN": 9.493684024709797, "DARUNAVIR": 153.4503916083696, "DESCOVY": 67.9189795859046, "DEXAMETHASONE": 1.6182611880818834, "DOLUTEGRAVIR": 203.1557820626649, "EFAVIRENZ": 236.99657015575752, "EMTRICITABINE": 156.74902480651065, "EMTRIVA": 297.824846055731, "EPIVIR": 60.00885722172054, "FILGRASTIM": 17.22886813102781, "FUZEON": 122.55659360463837, "GANCICLOVIR": 9.737013362436642, "GENVOYA": 25.972807278919174, "INDINAVIR": 37.928620840209845, "INFLIXIMAB": 8.846545418432335, "ISENTRESS": 55.12734084854807, "KALETRA": 24.57381358395608, "LAMIVUDINE": 240.4610028291607, "LEVOFLOXACIN": 1.0817835525941373, "LOPINAVIR": 26.93665728607972, "METHOTREXATE": 0.8413350664893698, "MYCOPHENOLATE": 2.537333217450452, "NORVIR": 36.19482630371997, "PREZISTA": 115.58123582248996, "RALTEGRAVIR": 165.08883489826445, "RITUXIMAB": 3.449409778609375, "STOCRIN": 50.74421148408263, "STRIBILD": 3.661143387132785, "TENOFOVIR": 12.867663194107063, "TIVICAY": 117.08157361621396, "TRIUMEQ": 21.4799484891294, "TRUVADA": 6.012529462054437, "VIREAD": 10.533889057586588, "null": 0.0678607906931149}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6068.json
index 51ab0aac83c..cdb8c6fd216 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6068.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6068.json
@@ -1 +1 @@
-{"null": 1.196302373580328}
\ No newline at end of file
+{"EMTRICITABINE": 274.1748553756677, "TRUVADA": 10.352984520321906}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6069.json
index 7359afb0fb0..4e6296b584d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6069.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6069.json
@@ -1 +1 @@
-{"BYETTA": 67.00228546997259, "ISENTRESS": 76.30225936932983, "JANUMET": 23.845881555043864, "JANUVIA": 31.445443621359328, "TRULICITY": 13.502031179557513, "VICTOZA": 35.71405912352257}
\ No newline at end of file
+{"DARUNAVIR": 177.74013742551838, "DOLUTEGRAVIR": 372.8722313325229, "EFAVIRENZ": 281.9161054116521, "EMTRICITABINE": 200.26380668698064, "TRUVADA": 6.891947290869579, "null": 0.1739018749937073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/607.json
index 87bc782ba27..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/607.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/607.json
@@ -1 +1 @@
-{"QUTENZA": 4101.869131213314}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6070.json
index e49c4efa583..c8712e437dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6070.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6070.json
@@ -1 +1 @@
-{"BYETTA": 32.80685181748222, "JANUMET": 21.921872454985728, "JANUVIA": 11.325499520086856, "LANTUS": 2.942740076789228, "VICTOZA": 51.11664283703716}
\ No newline at end of file
+{"ABACAVIR": 1.4548955681026097, "AIMOVIG": 1.3221666362696622, "ALEMTUZUMAB": 3.176451434817756, "ARAVA": 0.4746847450717478, "AUBAGIO": 0.9021495269895616, "AVAMYS": 3.089062592141616, "BELIMUMAB": 8.776419611016381, "BENLYSTA": 4.0110913209192605, "BOSULIF": 2.4220157521519208, "CICLOSPORIN": 0.3074529907870641, "CIMZIA": 0.5169475254034449, "COMIRNATY": 1.061367309913831, "COSENTYX": 2.09692529891269, "CYMBALTA": 0.4425606515100758, "ENBREL": 3.0209059794743425, "FASENRA": 2.351282927546486, "FORSTEO": 0.6110508527155633, "GARDASIL": 4.16992911048345, "HARVONI": 2.7879453791831583, "HUMALOG": 0.3806602202043788, "HUMIRA": 1.1664273916781738, "IBRANCE": 5.516356141983105, "KEYTRUDA": 1.0787220979466887, "LANTUS": 0.2020806662484064, "METHOTREXATE": 0.5440140457537803, "MMRVAXPRO": 0.5147071920922439, "NUCALA": 4.317294420820848, "OMALIZUMAB": 2.5670965135502763, "OZEMPIC": 22.49592856114517, "PEGASYS": 1.254955967049849, "PEGINTRON": 1.8357776095951424, "RAPAMUNE": 4.535879017358669, "REVLIMID": 4.048511256466765, "RIBAVIRIN": 2.439683977107897, "SHINGRIX": 1.4202237135279097, "SIMPONI": 2.8187040175534643, "SPIKEVAX": 0.7009690727131174, "STELARA": 0.844670984800545, "SUTENT": 1.924700929028524, "TOZINAMERAN": 1.993012001325653, "TRUVADA": 0.1449117918127392, "VAXZEVRIA": 0.2539818554823612, "VFEND": 2.1204680461567063, "XELJANZ": 6.306070419842226, "XOLAIR": 0.7756259858861166, "ZOSTAVAX": 29.044095689378377, "null": 0.6032081739228418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6071.json
index 5e644c4fcbe..c11161c4f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6071.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6071.json
@@ -1 +1 @@
-{"AFINITOR": 175.0589038120881, "BYETTA": 44.55632003066437, "CAPECITABINE": 29.616446771874728, "EVEROLIMUS": 144.42396150719617, "JANUMET": 8.786327447522655, "JANUVIA": 7.117943810599132, "LUTATHERA": 167.3917756535081, "SUTENT": 20.865581339530547}
\ No newline at end of file
+{"ABATACEPT": 0.5360856676539874, "ALEMTUZUMAB": 11.6177984892787, "ALISKIREN": 4.956591359390759, "APIXABAN": 0.5983346335628869, "ASPARAGINASE": 1.0329216079661294, "AUBAGIO": 0.3966607739239167, "AVASTIN": 1.772869404952375, "BEVACIZUMAB": 1.2271609279994795, "BRILIQUE": 1.6659809549883775, "BUSULFAN": 1.1167815627290656, "CAPSAICIN": 220.03782577967883, "CICLOSPORIN": 0.6244533037142538, "CLOPIDOGREL": 0.895258446409166, "COMIRNATY": 0.7454998647445632, "DEXAMETHASONE": 1.0027552663155117, "ELIQUIS": 0.6587083210689971, "ENTYVIO": 2.520634750720948, "FASENRA": 1.2268574416516995, "GANCICLOVIR": 2.686042786103918, "GARDASIL": 2.810102750169865, "HARVONI": 1.036477618904669, "HIZENTRA": 0.8972789370858634, "HUMALOG": 0.3352500653045948, "IBRANCE": 0.1924727034418412, "INTRONA": 3.9606177576914714, "IPILIMUMAB": 6.658732495992841, "JANUVIA": 0.7122944242655959, "KEPPRA": 0.3411163841332673, "KEYTRUDA": 5.552863011836945, "LEMTRADA": 44.37947752822445, "LEVOFLOXACIN": 0.417390455844203, "MMRVAXPRO": 6.732366864583718, "MODERNA": 0.8105125169983148, "NEXAVAR": 0.3391787508733287, "NIMENRIX": 1.7175415642364649, "NPLATE": 19.30216738565376, "OPDIVO": 3.2852145534871084, "PANTOPRAZOLE": 2.2240352308610585, "PEGASYS": 3.4697071477254227, "PEGINTERFERON": 4.159875894222123, "PEGINTRON": 2.62063852971095, "PEMBROLIZUMAB": 3.804638369177528, "PLAVIX": 1.2290743070989367, "PREVENAR": 25.744990034558345, "RIBAVIRIN": 2.3115701136270284, "ROTATEQ": 8.410311648318114, "SHINGRIX": 0.5402400108947587, "SOLIRIS": 0.4663304662248166, "SPIKEVAX": 0.5909172483472793, "STELARA": 0.3777174139877051, "SUTENT": 0.6234483852962114, "SYNAGIS": 1.3702512258195343, "TAMIFLU": 1.2954769531241077, "TOZINAMERAN": 1.516340586379426, "TRUVADA": 0.1244890465392686, "VAXZEVRIA": 1.4138876672151193, "VENETOCLAX": 2.607625791171775, "XOLAIR": 0.3653319359652849, "ZOSTAVAX": 0.4971937541995824, "ZYPREXA": 0.2724401511312693, "null": 0.8210559827642488}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6072.json
index bd6be900179..52667084a5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6072.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6072.json
@@ -1 +1 @@
-{"AFINITOR": 97.65212229684352, "BYETTA": 96.14014129169658, "CAPECITABINE": 46.18776361163071, "OLANZAPINE": 11.680702112028191, "SUTENT": 12.176925220462872}
\ No newline at end of file
+{"AXITINIB": 31.66471351948561, "DOXORUBICIN": 10.378304862037805, "IPILIMUMAB": 39.4604514723791, "KEYTRUDA": 259.55995157599045, "OPDIVO": 233.0824053732555, "PEMBROLIZUMAB": 12.180790553386824}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6073.json
index 4061922f487..b1d83127328 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6073.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6073.json
@@ -1 +1 @@
-{"ASPARAGINASE": 119.01717524869828, "BYETTA": 26.2798904508502, "JANUMET": 18.227238062616014, "JANUVIA": 11.084099614188649, "ONCASPAR": 91.4197460099163, "VICTOZA": 25.740166285726552, "ZYPREXA": 4.596008826205094}
\ No newline at end of file
+{"COMIRNATY": 0.1613056160797764, "IPILIMUMAB": 66.64906496063064, "KEYTRUDA": 106.52381131281108, "OPDIVO": 111.99013875702488, "PEMBROLIZUMAB": 218.3609962337172, "VAXZEVRIA": 0.1677068792423437, "null": 0.0217545925036319}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6074.json
index 1d91532de2f..d8f155c8d4f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6074.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6074.json
@@ -1 +1 @@
-{"BYETTA": 93.48750618786488, "JANUMET": 191.14148497573888, "JANUVIA": 101.2944267596451}
\ No newline at end of file
+{"IPILIMUMAB": 78.92881584574202, "KEYTRUDA": 134.23657725866886, "OPDIVO": 91.7969739074402, "PEMBROLIZUMAB": 225.40112169505903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6075.json
index 19e81e701ec..601d2aa6544 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6075.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6075.json
@@ -1 +1 @@
-{"BYETTA": 107.68938426721324, "JANUMET": 170.10795683074954, "JANUVIA": 242.48014885587503}
\ No newline at end of file
+{"KEYTRUDA": 360.8859773064907, "OPDIVO": 70.12170709435715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6076.json
index 763df1e0d48..a60703e88e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6076.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6076.json
@@ -1 +1 @@
-{"ACTOS": 2.014278443396581, "ADENURIC": 2.142315086416051, "ASPARAGINASE": 5.427743888188936, "AUBAGIO": 1.3859786399269594, "AVONEX": 2.7493343494663707, "AZATHIOPRINE": 3.7280473082584846, "BARACLUDE": 1.8060005453800676, "BIKTARVY": 1.6973502712080624, "BLINATUMOMAB": 3.1819150861582477, "BOSULIF": 1.5094296328519126, "BOSUTINIB": 10.562963266460804, "BRAFTOVI": 1.2400205121392276, "BYDUREON": 13.29379487448506, "BYETTA": 31.44804119598424, "CABOMETYX": 1.069491034779208, "CANCIDAS": 3.386882733663956, "CELLCEPT": 2.4164639259746905, "COAPROVEL": 1.4119446346340296, "COMBIVIR": 1.1042935700507874, "CRIXIVAN": 6.412639307063479, "CYTARABINE": 1.7168367162572205, "DASATINIB": 5.33977684664884, "DESCOVY": 2.631736997926445, "DULAGLUTIDE": 6.625808673154866, "EBIXA": 2.5104449071063395, "EFAVIRENZ": 1.578678386485412, "ENTYVIO": 1.8301642683850785, "EPCLUSA": 1.945203977686066, "EPIVIR": 5.453320870769771, "ERLOTINIB": 7.54355080424299, "ESOMEPRAZOLE": 1.3614034876574677, "EUCREAS": 12.53858841408445, "FEBUXOSTAT": 1.3410937102808889, "FORTOVASE": 7.360631430953967, "FORXIGA": 2.0965333584408072, "GALVUS": 9.407410761028077, "GLIBENCLAMIDE": 1.0957491134219808, "HIZENTRA": 1.0220785910414898, "HUMIRA": 1.4575558790349388, "ICLUSIG": 11.03762090090398, "INCIVO": 1.8273823480144524, "INDINAVIR": 3.195000741685373, "INFLIXIMAB": 2.671741040550064, "INTRONA": 2.083909232317406, "INVIRASE": 6.803109053075297, "INVOKANA": 5.049986261556998, "IPILIMUMAB": 1.7270494480498673, "ISENTRESS": 2.135222387905285, "JANUMET": 27.626295296434662, "JANUVIA": 36.443906758260574, "JARDIANCE": 3.912976009527797, "KALETRA": 2.961680146897196, "KALYDECO": 6.814419662396732, "KEPPRA": 1.656985178089405, "KEYTRUDA": 1.7956853104882298, "LAMIVUDINE": 2.1340268536953126, "LANTUS": 1.0173724248542368, "LENVIMA": 1.4620130734252283, "LEVEMIR": 1.3537390490901875, "LIRAGLUTIDE": 7.79640321688138, "LOPINAVIR": 1.0592147232582785, "MEKINIST": 1.1523071269570944, "MERCAPTOPURINE": 6.481835431929405, "METFORMIN": 1.731615636031565, "METHOTREXATE": 1.0697522482772048, "MICARDISPLUS": 2.8276290756533724, "MOUNJARO": 12.105980806309844, "MULTAQ": 1.1943722761976103, "NEVIRAPINE": 2.6717245412653083, "NEXAVAR": 1.6471620765377597, "NILOTINIB": 4.563984729764407, "NIVOLUMAB": 1.743430498243685, "NORVIR": 3.62235554795027, "NOVONORM": 2.964748557750767, "NOXAFIL": 1.2710063011505748, "OFEV": 1.449374258149571, "OLYSIO": 1.1003718213806992, "ONCASPAR": 30.006224014559614, "ONGLYZA": 14.258198894708364, "OPDIVO": 1.5767567616514462, "ORKAMBI": 1.0105047666348537, "OZEMPIC": 4.855400812138701, "PANTOPRAZOLE": 1.0504741706300162, "PEGASPARGASE": 5.48124796280896, "PEGASYS": 1.6604476022321992, "PEGINTERFERON": 1.1928297213618488, "PEGINTRON": 1.640802183990365, "REMICADE": 1.828822312768129, "REVESTIVE": 5.047738816970853, "REYATAZ": 5.913890930661339, "RILUTEK": 6.768214897223107, "RITONAVIR": 3.286040564070988, "ROACTEMRA": 1.1525762523723473, "RUCONEST": 1.006310409288213, "RYBELSUS": 19.22416033733675, "SAXENDA": 27.253388124166133, "SCEMBLIX": 11.790948559960835, "SPRYCEL": 1.4059965415469309, "STAVUDINE": 11.936607486507832, "SUSTIVA": 3.2123651582107637, "SUTENT": 1.0452483079998218, "TAMIFLU": 1.0666820321355162, "TASIGNA": 8.25315426615855, "TIVICAY": 2.5533012752926343, "TOCILIZUMAB": 1.2670312701704476, "TOUJEO": 1.2421264363534903, "TRIUMEQ": 3.15892929738473, "TRULICITY": 29.629314673776637, "VEDOLIZUMAB": 3.0795259033172697, "VEKLURY": 1.2955868991958304, "VELMETIA": 23.734504115941363, "VICTOZA": 72.59033108836931, "VIRAMUNE": 3.915676478387241, "VIREAD": 1.8496287127634707, "VOTRIENT": 2.1518282849842776, "YERVOY": 1.0160284835181352, "ZELBORAF": 1.1874904835313504, "ZEPATIER": 1.5535744427246012, "ZERIT": 22.351247477085668, "ZIAGEN": 2.743751463134501, "ZYPREXA": 5.188768890673827}
\ No newline at end of file
+{"KEYTRUDA": 82.34998384098816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6077.json
index 9dea0505190..5c8c45049e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6077.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6077.json
@@ -1 +1 @@
-{"ADENURIC": 6.241606018796652, "ADVAGRAF": 8.633271691888433, "AERIUS": 2.340191892769533, "APROVEL": 3.834585210596814, "ASPARAGINASE": 13.164815233504898, "AXITINIB": 2.2003738649165308, "AZATHIOPRINE": 1.7885990369694955, "BIKTARVY": 1.8545398133425373, "BRAFTOVI": 2.0701855016824218, "BUSULFAN": 1.090565086357136, "BYDUREON": 7.457948544560627, "BYETTA": 24.718934351883235, "CANCIDAS": 2.73345514031356, "CELLCEPT": 2.8882362560647774, "COAPROVEL": 5.01959918926064, "COMBIVIR": 2.146778328158112, "COTELLIC": 2.198002288287974, "CRIXIVAN": 3.488385110481233, "CYTARABINE": 1.8876411363923464, "DELAMANID": 1.8716010004622992, "DEXAMETHASONE": 1.910505193748005, "DULAGLUTIDE": 3.0738798159934837, "EBIXA": 6.577299342398249, "EMEND": 3.350705271393696, "EMPAGLIFLOZIN": 3.746006424900579, "EMTRICITABINE": 3.033080190170774, "ENTYVIO": 1.1931978553837577, "EPIVIR": 2.743474523763604, "ESOMEPRAZOLE": 7.175900814347076, "EUCREAS": 23.31092100895109, "FEBUXOSTAT": 1.8567528796547597, "FORXIGA": 1.3965808682194183, "GALVUS": 13.386847840851493, "GEFITINIB": 3.5635039625955947, "HARVONI": 1.2780503256472815, "ICANDRA": 23.105299434417457, "ICLUSIG": 5.193429312729352, "INCIVO": 3.8287733213352526, "INTELENCE": 3.90052859478247, "INVIRASE": 6.8706616635760085, "INVOKANA": 6.816723529365103, "IRBESARTAN": 1.0726222248875246, "IRESSA": 1.2807867976788476, "ISENTRESS": 3.35181563404807, "JANUMET": 17.099378456043898, "JANUVIA": 24.847722364374416, "JARDIANCE": 2.162766703271535, "KALETRA": 3.4857999729663933, "KALYDECO": 2.57172234377964, "KEPPRA": 1.1913904493927998, "KIVEXA": 3.981455186552933, "LACOSAMIDE": 1.5392441064572198, "LENVIMA": 1.7183309426239444, "LEVEMIR": 1.101931043123996, "LIRAGLUTIDE": 13.412222145481731, "MERCAPTOPURINE": 6.95560824244525, "METFORMIN": 4.618796183190683, "MIDAZOLAM": 1.329082807590074, "NEXAVAR": 3.215301896133324, "NILOTINIB": 4.265214066736592, "NORVIR": 2.147938191645139, "NOXAFIL": 1.325953272012913, "OLANZAPINE": 1.2471075289764977, "ONCASPAR": 24.737938345639527, "ONGLYZA": 18.78576684086436, "OZEMPIC": 5.38146513186418, "PEGASYS": 1.117846462852624, "PEGINTERFERON": 2.693064518090718, "PEGINTRON": 2.2729548882269266, "PRADAXA": 2.6475803914390323, "REMICADE": 1.7894520269001193, "REPAGLINIDE": 5.093129475791856, "REYATAZ": 3.938583819082288, "RILUTEK": 12.25409631709886, "RILUZOLE": 15.922121402782386, "RISPERIDONE": 1.2181159625535525, "ROACTEMRA": 2.470161641379549, "RYBELSUS": 14.244427534332155, "SAXENDA": 11.630526219325995, "SIMEPREVIR": 7.570739143679191, "SOMATROPIN": 6.354695258301056, "SOVALDI": 2.857094945402418, "SPECTRILA": 73.61796610087383, "SUSTIVA": 12.270590573638067, "TAMIFLU": 1.358338495176456, "TASIGNA": 4.089603474774221, "TIGECYCLINE": 7.469700010507458, "TOCILIZUMAB": 2.2222536563324087, "TRIUMEQ": 2.332336366873145, "TRULICITY": 12.953750442096418, "VEKLURY": 3.737774416605651, "VELMETIA": 39.9984755530353, "VICTOZA": 48.316839087891495, "VILDAGLIPTIN": 15.667470033671016, "VIREAD": 1.074725873968572, "VOTRIENT": 1.5512993847943533, "XELEVIA": 63.37477913824392, "ZELBORAF": 1.436637375302675, "ZERIT": 21.72216881088159, "ZYPREXA": 2.774000244627797, "null": 1.2932527560886844}
\ No newline at end of file
+{"IPILIMUMAB": 98.94122353716833, "KEYTRUDA": 93.1636683543367, "OPDIVO": 385.580392753696, "PEMBROLIZUMAB": 110.28158389102845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6078.json
index 06ac72676f9..e22a9c4789e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6078.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6078.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 8.890763123775479, "BOSULIF": 10.71252557069622, "BUPRENORPHINE": 4.602314932703579, "BYETTA": 92.87566972861912, "JANUMET": 34.558062817423206, "JANUVIA": 33.63753706259275, "LANTUS": 1.8967562281542707, "SUBOXONE": 2.418093236825073, "TRULICITY": 5.617763541971441, "VICTOZA": 21.43339116978135, "ZYPREXA": 4.508069701474809}
\ No newline at end of file
+{"COMIRNATY": 0.1439611497090261, "IPILIMUMAB": 284.9756724361475, "KEYTRUDA": 105.58378738220324, "OPDIVO": 68.50200807486466, "PEMBROLIZUMAB": 88.12473905802388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6079.json
index 1c8fe629914..66c6308b86b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6079.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6079.json
@@ -1 +1 @@
-{"BUSULFAN": 35.44391106075367, "BYETTA": 20.424036291162206, "OLANZAPINE": 10.231150068199211, "null": 1.6388511278600713}
\ No newline at end of file
+{"KEYTRUDA": 88.82567202993074, "OPDIVO": 135.6052457121074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/608.json
index 620cc67a80f..69243662961 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/608.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/608.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 15.44300794738935, "EVRA": 126.4377489659286, "null": 8.363043486911334}
\ No newline at end of file
+{"XALKORI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6080.json
index bdb612fa628..a5a60ce0074 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6080.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6080.json
@@ -1 +1 @@
-{"ASPARAGINASE": 36.922295647503525, "BYETTA": 21.51144230105459, "CELLCEPT": 8.09783630329994, "CRIXIVAN": 16.038000960695626, "DEXAMETHASONE": 2.1113548783793994, "FORXIGA": 6.584749238463214, "JANUMET": 9.83296340018686, "JANUVIA": 18.4426117276304, "JARDIANCE": 7.3300810337044915, "MERCAPTOPURINE": 25.499085566225485, "NORVIR": 14.842834958997877, "OLANZAPINE": 5.879915436039491, "ONCASPAR": 142.5177441968473, "PEGASYS": 1.3842625376626398, "PEGINTRON": 1.684539006185121, "SAXENDA": 11.273877099815111, "TRULICITY": 6.181048234022347, "VICTOZA": 20.419665985565064, "ZYPREXA": 2.225011387348092}
\ No newline at end of file
+{"ABRAXANE": 17.59032851999298, "ALIMTA": 3.896940114643466, "AXITINIB": 13.01462744852356, "BRAFTOVI": 15.094653764235456, "CABOMETYX": 4.611622776121585, "INFLIXIMAB": 15.64998902019602, "INLYTA": 2.363354522636749, "IPILIMUMAB": 296.79190779537004, "KEYTRUDA": 138.07273477819757, "NIVOLUMAB": 19.21659460783954, "OPDIVO": 153.57751843105626, "PEMBROLIZUMAB": 87.01238917414331, "YERVOY": 9.312142354077356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6081.json
index 126f2e80da1..b457d20f7f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6081.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6081.json
@@ -1 +1 @@
-{"ATRIPLA": 1.0467854449933682, "BYETTA": 46.569648047079085, "JANUVIA": 8.513367501894463, "JARDIANCE": 7.578264123282696, "MEPOLIZUMAB": 25.943104994050174, "STELARA": 4.349670037640452, "ZYPREXA": 4.3143328506515095}
\ No newline at end of file
+{"IPILIMUMAB": 154.62525109794524, "KEYTRUDA": 108.89261895590786, "OPDIVO": 80.50611893721674, "PEMBROLIZUMAB": 138.7524362437781}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6082.json
index 8a0304896ad..f7f188c5b5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6082.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6082.json
@@ -1 +1 @@
-{"JANUVIA": 251.8054739786547}
\ No newline at end of file
+{"ALIMTA": 11.472469817689513, "AXITINIB": 87.09529715629557, "BRAFTOVI": 15.801275667181104, "CABOMETYX": 10.44435535647333, "INLYTA": 23.705167993430408, "IPILIMUMAB": 32.07000010915875, "KEYTRUDA": 191.10903942150597, "OPDIVO": 206.16830038711043, "PEMBROLIZUMAB": 17.701328577193927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6083.json
index f81557f657f..0621cda8ba9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6083.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6083.json
@@ -1 +1 @@
-{"ABRAXANE": 1.1373758948084116, "ADCETRIS": 3.3333090118730357, "ADCIRCA": 1.4668660362376835, "ADENURIC": 4.301883514820562, "ADVAGRAF": 5.262442904968156, "AFINITOR": 1.4763503440041907, "ALEMTUZUMAB": 5.134437082651225, "ALIMTA": 19.1483356397338, "ALL": 2.192959408731116, "AMIKACIN": 2.3218026713617226, "ANIDULAFUNGIN": 3.9428006652885976, "APROVEL": 2.5663896581921195, "ARANESP": 2.021827558114906, "ASPARAGINASE": 3.876722608542614, "AVASTIN": 1.6894345259417796, "AXICABTAGENE": 7.408489041631926, "AZACITIDINE": 12.151355792967754, "AZATHIOPRINE": 2.868270710557398, "BARACLUDE": 2.9125412406315285, "BASILIXIMAB": 5.230846874129729, "BEVACIZUMAB": 1.966959419259455, "BLINATUMOMAB": 6.2513125465939545, "BLINCYTO": 5.55301388025667, "BOCEPREVIR": 5.589816312299018, "BORTEZOMIB": 4.806276840060104, "BOSULIF": 1.024363739538778, "BOSUTINIB": 4.393682976373812, "BUSULFAN": 9.019469751530236, "CAELYX": 5.75086480447691, "CANCIDAS": 4.565684632829624, "CAPECITABINE": 2.6676738068405887, "CARFILZOMIB": 5.327846393984082, "CARMUSTINE": 10.547358989551524, "CASPOFUNGIN": 2.709874113172724, "CELLCEPT": 8.208864627071813, "CELSENTRI": 2.8369679267689256, "CHLORMETHINE": 11.617859482661585, "CICLOSPORIN": 3.025415179280812, "CIDOFOVIR": 8.245672673576786, "CLADRIBINE": 38.17989303271306, "CLOFARABINE": 8.462996114289497, "COAPROVEL": 2.0262058440159234, "COMBIVIR": 6.285346772838557, "CRIXIVAN": 1.8774720824984068, "CUBICIN": 3.6665253818099344, "CYTARABINE": 9.118206841572222, "DACOGEN": 11.229998603806642, "DAPTOMYCIN": 3.454615316456632, "DARATUMUMAB": 2.353610609415271, "DARZALEX": 5.218177044952263, "DASATINIB": 3.66827926951917, "DECITABINE": 11.807840480875372, "DEXAMETHASONE": 4.536571299964305, "DIFICLIR": 5.893151436169882, "DOCETAXEL": 1.2650321890798877, "DOLUTEGRAVIR": 2.3538100855586124, "DOXORUBICIN": 7.601580795610622, "EFAVIRENZ": 1.3628092525851532, "ELTROMBOPAG": 17.374029516055028, "EMEND": 1.3910860419718925, "EMTRICITABINE": 2.0240553773343986, 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1.9445302897286876, "KEPPRA": 2.967371999404607, "KEYTRUDA": 1.3920962112380493, "KISQALI": 2.684617507136792, "KYMRIAH": 6.835060632109216, "KYPROLIS": 4.412198175842415, "LAMIVUDINE": 2.6711823353871, "LEFLUNOMIDE": 2.0534196917129237, "LEVETIRACETAM": 1.7082294133206426, "LONSURF": 4.316328080531182, "LOPINAVIR": 1.3235821760526885, "LUTATHERA": 3.920631046771508, "LYNPARZA": 4.860710280438424, "MABCAMPATH": 12.059216786587651, "MABTHERA": 8.996925630102426, "MEKINIST": 1.1360347123037993, "MELPHALAN": 7.517998685250997, "MERCAPTOPURINE": 15.927044981458106, "METHOTREXATE": 7.106972193635807, "MIRCERA": 1.229066764442514, "MYCOPHENOLATE": 3.3596866918737027, "NEORECORMON": 9.79841557335311, "NEULASTA": 2.3144378357026536, "NILOTINIB": 5.354800560503826, "NINLARO": 1.362884889838177, "NOT": 1.0598935940703151, "NOXAFIL": 2.8009232853139765, "NPLATE": 2.8743240396404888, "OBINUTUZUMAB": 2.248656063809772, "OLAPARIB": 5.098888063138287, "OLOPATADINE": 10.366808009349796, "PACLITAXEL": 3.6361545709060583, "PANTOPRAZOLE": 1.4411444535583728, "PEGASPARGASE": 7.840648745542014, "PEGASYS": 5.848013727865227, "PEGINTERFERON": 6.1828429366359225, "PEGINTRON": 4.301841055928266, "PEMBROLIZUMAB": 3.2001865606127686, "PEMETREXED": 10.621235728969689, "PLAVIX": 1.3642403103771157, "PLUVICTO": 10.108843906607506, "POMALIDOMIDE": 9.382844790844969, "POSACONAZOLE": 2.1410013034757966, "RADIATION": 4.530630819096461, "RAPAMUNE": 1.094265185504502, "REBETOL": 2.3564283355813016, "REMICADE": 1.1656408448752595, "REVLIMID": 5.8856370015526, "RIBAVIRIN": 2.9024323561220244, "RITUXIMAB": 4.400352041460621, "RIXATHON": 3.110215357561937, "ROACTEMRA": 1.740578060520013, "RUBRACA": 1.3119831028483773, "RUXOLITINIB": 3.4887651396967585, "SCEMBLIX": 10.519882618710938, "SOLIRIS": 2.0656798948700525, "SPRYCEL": 5.441121560058406, "SUTENT": 1.5203717349682555, "TACROLIMUS": 1.6616847351464517, "TAGRISSO": 1.2217903321688115, "TASIGNA": 6.349180443577289, "TAXOTERE": 3.252733923666057, "TEMODAL": 30.691148650726, "TEMOZOLOMIDE": 20.55017296647523, "THALIDOMIDE": 4.191613805125339, "THIOTEPA": 2.3438655669244155, "TOCILIZUMAB": 1.1283416813701, "TOPOTECAN": 14.640763910154396, "TORISEL": 2.0059226652056497, "TRABECTEDIN": 13.470615035928716, "TRISENOX": 4.657562294120532, "TRODELVY": 4.168216564960286, "VELCADE": 7.039671369657623, "VENCLYXTO": 7.634495276913012, "VENETOCLAX": 7.896441014530584, "VFEND": 2.463818572158823, "VORICONAZOLE": 1.4382865602463726, "VYXEOS": 7.139146307915707, "XELODA": 3.3775782223168496, "XOFIGO": 9.63964719827858, "YESCARTA": 7.294153515095287, "YONDELIS": 21.793830302109644, "YTTRIUM90": 42.12177304765153, "null": 1.1843504964265246}
\ No newline at end of file
+{"ALIMTA": 5.003016610445751, "AVELUMAB": 55.05827703969306, "AXITINIB": 26.969937630686196, "BEVACIZUMAB": 4.856755224126911, "IPILIMUMAB": 388.0625496062652, "KEYTRUDA": 87.40822405458994, "OPDIVO": 99.53363435730144, "PACLITAXEL": 18.712096058685947, "PEMBROLIZUMAB": 159.58314858683067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6084.json
index c5844f0da5c..47f139a4547 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6084.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6084.json
@@ -1 +1 @@
-{"ABILIFY": 1.6222285346844956, "AIMOVIG": 2.133936587057049, "BENLYSTA": 1.075499067529223, "BIKTARVY": 1.0593692987671763, "BRINTELLIX": 3.93591986177056, "BRIVIACT": 1.6620944591939262, "CANNABIDIOL": 3.5010844484843004, "CHAMPIX": 10.056562003766496, "CYMBALTA": 4.36698777095376, "DULOXETINE": 2.3384774351807143, "ELLAONE": 2.076656878830349, "ESOMEPRAZOLE": 1.2321547472018597, "GARDASIL": 1.8971591912514247, "HUMAN": 1.176180169265595, "HUMIRA": 1.4554550152565795, "IRBESARTAN": 1.4786961451008436, "KAFTRIO": 2.81115648154628, "KEPPRA": 2.587018937301792, "LATUDA": 6.119671745237946, "LEVOFLOXACIN": 1.3019714614548925, "LYRICA": 2.8579206817138045, "NORVIR": 1.2337672633055738, "OLANZAPINE": 1.2275585751224638, "OXYBUTYNIN": 2.183191114284211, "PEGASYS": 1.972902341629219, "PEGINTRON": 1.007002256237549, "PREGABALIN": 1.3045174394747387, "REMICADE": 1.4212748164147968, "SIFROL": 2.224470168023422, "STALEVO": 1.6086270020461395, "SUBOXONE": 2.888701964811584, "TAMIFLU": 2.862934426803805, "TOZINAMERAN": 1.3110934110239083, "TRELEGY": 1.8381656148417684, "TRIUMEQ": 2.3615591326696896, "VIMPAT": 1.3508372655550684, "XYREM": 5.907251742015056, "ZYPREXA": 1.5200853772645022, "null": 1.8693574011276477}
\ No newline at end of file
+{"AXITINIB": 56.15157551640022, "IPILIMUMAB": 56.0123608654396, "KEYTRUDA": 323.0591191024658, "OPDIVO": 59.723152833924566, "PEMBROLIZUMAB": 79.04636038738231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6085.json
index 0ec31114a09..cc9211509f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6085.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6085.json
@@ -1 +1 @@
-{"ABILIFY": 2.140331538996817, "AIMOVIG": 2.3617556178445547, "ARIPIPRAZOLE": 5.8393192665911, "BRINTELLIX": 2.914758262985242, "BUPRENORPHINE": 4.889299511850244, "BYETTA": 2.32823854958584, "CHAMPIX": 9.376908754594163, "CYMBALTA": 3.300305981206497, "GARDASIL": 1.713043935572801, "RISPERIDONE": 15.532924596578226, "ZOSTAVAX": 1.9618951677225545, "null": 2.417258715672065}
\ No newline at end of file
+{"IPILIMUMAB": 856.2227396132345, "KEYTRUDA": 42.80984948074083, "OPDIVO": 136.43005773823856, "PEMBROLIZUMAB": 68.77202184071163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6086.json
index 476345d908d..81e966383f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6086.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6086.json
@@ -1 +1 @@
-{"ABILIFY": 8.749059074626432, "BRINTELLIX": 3.175111381907692, "CHAMPIX": 10.437362256158758, "CYMBALTA": 2.249350837383586, "KEPPRA": 1.1893147662956156, "LATUDA": 3.1106919729643723, "OMALIZUMAB": 1.7783656063528313, "TAMIFLU": 3.8643770514106337, "TOZINAMERAN": 1.5452990881393966, "VIAGRA": 2.983754783082659, "ZYPREXA": 1.307835246667177, "null": 2.5282716852007785}
\ No newline at end of file
+{"AXITINIB": 75.92011247818438, "INLYTA": 6.001825255850177, "IPILIMUMAB": 44.30409769261316, "KEYTRUDA": 420.75978740058224, "OPDIVO": 55.93186619878118, "PACLITAXEL": 11.46201496584662, "PEMBROLIZUMAB": 108.50116229004126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6087.json
index f87c8206518..40e7e829d43 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6087.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6087.json
@@ -1 +1 @@
-{"ABATACEPT": 7.340176358882203, "ADALIMUMAB": 8.630721533950622, "ALIMTA": 3.682938896503301, "APREMILAST": 53.17751302090653, "ARAVA": 2.265618622220262, "ASPARAGINASE": 4.642960968138163, "BETAFERON": 13.03687385137447, "CICLOSPORIN": 5.917115874017986, "CIMZIA": 1.0720160407806107, "COTELLIC": 34.98819975996297, "DABRAFENIB": 33.217689177885575, "ENBREL": 57.87496223132836, "FORSTEO": 1.66442988896085, "INCIVO": 4.639197831916441, "KEYTRUDA": 1.0780241426537698, "MEKINIST": 33.126236917580684, "ROACTEMRA": 5.677589710435543, "SOMATROPIN": 25.471415284247072, "VEMURAFENIB": 79.29499705804155, "ZELBORAF": 17.593938575093958}
\ No newline at end of file
+{"ALIMTA": 5.836701153509392, "CABOMETYX": 5.669339994370568, "IPILIMUMAB": 130.25320983857247, "KEYTRUDA": 117.04968577415124, "NIVOLUMAB": 43.140781727226496, "OPDIVO": 152.35088760516322, "PEMBROLIZUMAB": 252.2892549395408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6088.json
index 8632d1f00c9..122e82d2c6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6088.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6088.json
@@ -1 +1 @@
-{"null": 7.99712037139817}
\ No newline at end of file
+{"IPILIMUMAB": 105.08007748062978, "KEYTRUDA": 160.68548473043376, "OPDIVO": 37.014866421035, "PEMBROLIZUMAB": 142.77021930411232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6089.json
index 29f5f45a493..5f8aa00d852 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6089.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6089.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 170.29637498110682}
\ No newline at end of file
+{"AXITINIB": 46.67011933359792, "IPILIMUMAB": 229.4228018276204, "KEYTRUDA": 126.54382685086368, "OPDIVO": 71.98375210372812, "PEMBROLIZUMAB": 222.94764746283224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/609.json
index c9a277e7e5b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/609.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/609.json
@@ -1 +1 @@
-{"COMIRNATY": 3.5231563466910822, "COVID19": 1.162621800718408, "SPIKEVAX": 1.7117530571155843, "VAXZEVRIA": 1.645326874981367}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6090.json
index 1a4ab99e9d6..8074671bee7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6090.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6090.json
@@ -1 +1 @@
-{"BYETTA": 76.32777601954106, "CICLOSPORIN": 11.12658135469201, "COSENTYX": 3.118088943510042, "ESOMEPRAZOLE": 59.179539972509694, "NEXAVAR": 9.220969723878095, "SAXENDA": 22.8405449442475, "SIMPONI": 4.140200018149041, "TRULICITY": 6.215948186476563, "VICTOZA": 79.29530607505393}
\ No newline at end of file
+{"COMIRNATY": 0.0567488453971936, "IPILIMUMAB": 106.29353756716668, "KEYTRUDA": 84.436120092004, "OPDIVO": 53.16995419712262, "PEMBROLIZUMAB": 163.01045574735727, "TOZINAMERAN": 0.4210521877730031, "null": 0.6153675847955242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6091.json
index 7b6a6d656ae..950b3f35a5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6091.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6091.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 3.65535516676802, "ASPARAGINASE": 3.28688134670332, "BEOVU": 17.215404632937354, "CICLOSPORIN": 4.102515332321778, "DOXORUBICIN": 8.555582261201163, "GARDASIL": 1.5970441244572195, "KAFTRIO": 19.145455473209356, "KEPPRA": 1.5540227654508478, "LEVETIRACETAM": 1.4599275041913884, "MEKINIST": 4.668197301718378, "MULTAQ": 4.683874972733009, "OLANZAPINE": 1.0152742250564304, "OMNITROPE": 46.948165393100005, "PEGASYS": 2.7331147756334957, "PEGINTRON": 6.061506012587965, "SOMATROPIN": 23.66846701604428, "STELARA": 1.1097178130953789, "TASIGNA": 2.919851787487163, "TESTOSTERONE": 18.204226209297303, "VFEND": 9.290576519719766, "VIAGRA": 5.251589461528071, "XOLAIR": 1.0390422537131203, "null": 1.4153767454217294}
\ No newline at end of file
+{"IPILIMUMAB": 268.11830719659974, "KEYTRUDA": 82.38302522030115, "OPDIVO": 108.7827885815122, "PEMBROLIZUMAB": 97.78667643242784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6092.json
index 330cdd7aee3..cd47b5d4362 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6092.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6092.json
@@ -1 +1 @@
-{"COMBIVIR": 118.6214886852543}
\ No newline at end of file
+{"KEYTRUDA": 71.5712175749142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6093.json
index 9172852404e..0d17356a1c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6093.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6093.json
@@ -1 +1 @@
-{"CICLOSPORIN": 5.264544089488227, "CIMZIA": 2.1577202957596198, "GARDASIL": 136.76112806333907, "RINVOQ": 6.841144726359089, "SILGARD": 421.0598913020565, "SIMPONI": 4.7816475224493775, "STELARA": 10.148003900572236}
\ No newline at end of file
+{"COMIRNATY": 0.5210957143503071, "IPILIMUMAB": 162.24804260204309, "KEYTRUDA": 42.05285796278237, "OPDIVO": 37.32379813315822, "PEMBROLIZUMAB": 76.48327868180448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6094.json
index b0f64ce2a0e..913f2bd1424 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6094.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6094.json
@@ -1 +1 @@
-{"AIMOVIG": 1.2770439438338377, "APIDRA": 1.1601362818561851, "BRIDION": 2.642705488493004, "CICLOSPORIN": 2.8982022379645214, "COSENTYX": 4.101512271149069, "DESLORATADINE": 6.877681052032816, "DEXAMETHASONE": 1.0611292895775046, "LAMIVUDINE": 4.64319458223776, "LEVOFLOXACIN": 2.499594359053298, "MEPOLIZUMAB": 1.9361516814625317, "METFORMIN": 4.364007459109607, "MMRVAXPRO": 2.9653925426285235, "MYCOPHENOLATE": 3.662419762310765, "OMALIZUMAB": 2.2521682669237126, "OPTIMARK": 3.125187504547718, "PEGINTERFERON": 2.158713462508949, "RINVOQ": 2.0767886461909986, "XOLAIR": 1.9276009364716884, "ZOSTAVAX": 1.025851874889474, "null": 2.854510586496244}
\ No newline at end of file
+{"IPILIMUMAB": 89.0312362604972, "KEYTRUDA": 175.42420859062494, "OPDIVO": 105.10613000328917, "PEMBROLIZUMAB": 106.9043138221212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6095.json
index 3b45948c62f..6801eac8de0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6095.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6095.json
@@ -1 +1 @@
-{"OPSUMIT": 64.5026697992598, "TRACLEER": 31.727211363231174, "null": 1.358069506289637}
\ No newline at end of file
+{"KEYTRUDA": 86.45374871324714}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6096.json
index eabcb6af384..ae05b4ff9be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6096.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6096.json
@@ -1 +1 @@
-{"AIMOVIG": 52.13227418084397, "ARIPIPRAZOLE": 5.962776736786875, "CIMZIA": 1.118684898294595, "COSENTYX": 4.452448100510977, "DEXAMETHASONE": 5.088742267003961, "EFAVIRENZ": 34.394895656535255, "ERENUMAB": 303.9100530685184, "LEVETIRACETAM": 6.250227453284563, "LEVOFLOXACIN": 3.201428477403569, "LURASIDONE": 98.99268137396714, "MIDAZOLAM": 32.84851213305368, "OLANZAPINE": 1.4965061455050723, "SIMPONI": 4.528254006373663, "STELARA": 1.4615572258316845, "null": 1.944170769134384}
\ No newline at end of file
+{"KEYTRUDA": 128.76169506023538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6097.json
index 19c062499ae..d9cd16d2ef8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6097.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6097.json
@@ -1 +1 @@
-{"null": 2.387804269380746}
\ No newline at end of file
+{"KEYTRUDA": 231.1845178685836, "OPDIVO": 98.88086835554972, "PEMBROLIZUMAB": 41.02675963556282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6098.json
index b03ba5ea5a4..b9f9a5df68c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6098.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6098.json
@@ -1 +1 @@
-{"CIMZIA": 26.15502052521021, "COSENTYX": 28.843392104841904}
\ No newline at end of file
+{"IPILIMUMAB": 349.93941749374187, "KEYTRUDA": 61.852379535659175, "OPDIVO": 85.8837163156792, "PEMBROLIZUMAB": 272.9166595203233}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6099.json
index faacf9807d4..92a8503bc8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6099.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6099.json
@@ -1 +1 @@
-{"AIMOVIG": 2.331078459727568, "AJOVY": 2.8224126900494286, "ALOXI": 1.2833906127806003, "ANAGRELIDE": 2.340609127628494, "AUBAGIO": 3.2045524005492, "CAPECITABINE": 1.6115126301504306, "CETUXIMAB": 1.0144170098887964, "CIRCADIN": 1.1161669489826802, "COLISTIMETHATE": 1.9391546785202023, "COMIRNATY": 3.043902393474709, "COVID19": 1.7786083356130775, "CYMBALTA": 2.7454436504055706, "ERENUMAB": 1.0244469742508864, "FAMPRIDINE": 1.5197792208636738, "FAMPYRA": 1.3724432670294329, "FIRDAPSE": 2.8597808828072098, "FLUCELVAX": 2.050604051519783, "GARDASIL": 1.8541664635701405, "GILENYA": 1.575525551558451, "INVIRASE": 1.279430744375882, "IRINOTECAN": 1.0841468245400134, "JCOVDEN": 1.7271298561324522, "KESIMPTA": 1.6582452114081103, "MICARDISPLUS": 1.2637675996875035, "MIMPARA": 1.1088109350183952, "NATPAR": 2.9420328543551912, "NEUPRO": 3.0162274619266016, "OCRELIZUMAB": 1.2570208255323003, "ONTRUZANT": 7.451828323924774, "OPTIMARK": 4.294114252058795, "PANITUMUMAB": 2.317240975091024, "PERTUZUMAB": 1.1611079400571085, "QUTENZA": 1.4804315298936774, "SHINGRIX": 1.793515693605475, "SILGARD": 1.1875031647769294, "SPIKEVAX": 1.6181294033627502, "TERIFLUNOMIDE": 1.4817266460799894, "THALIDOMIDE": 2.4860527681080287, "TOZINAMERAN": 2.0028237766459056, "TWINRIX": 3.211297657009865, "VAXZEVRIA": 1.976104106789802, "VEDOLIZUMAB": 1.4709698822398125, "XELODA": 1.653424206778893}
\ No newline at end of file
+{"IPILIMUMAB": 237.77810539460356, "KEYTRUDA": 130.04163197438356, "OPDIVO": 54.84933703834195, "PEMBROLIZUMAB": 87.2453277067317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/61.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/61.json
index abaf8df8d9c..72dd53dc330 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/61.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/61.json
@@ -1 +1 @@
-{"SIMPONI": 8.94645775188156}
\ No newline at end of file
+{"COMIRNATY": 0.7099543544015016, "EYLEA": 15.951871935728416, "MEPOLIZUMAB": 11.501171529391137, "PEGINTRON": 2.084322590103024, "SPIKEVAX": 0.5227552480129227, "TOZINAMERAN": 1.231236388160455, "VAXZEVRIA": 0.8459843877201576, "null": 1.3759229180045156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/610.json
index 45007505f08..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/610.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/610.json
@@ -1 +1 @@
-{"VAXZEVRIA": 2.7826950218070405, "null": 1.1089262244170963}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6100.json
index 2fb33a02748..fcb78cf58d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6100.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4632555735142945, "null": 1.7599662436797368}
\ No newline at end of file
+{"APIXABAN": 2.673677519431933, "COMIRNATY": 48.547612919493005, "PRIVIGEN": 0.7852494746157516, "SPIKEVAX": 0.0509499248151598, "TOZINAMERAN": 4.138153125225917, "VAXZEVRIA": 0.059683896607743, "null": 0.0015373119865317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6101.json
index 9ae73bffd04..7b80f751820 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6101.json
@@ -1 +1 @@
-{"null": 3.0600123374239803}
\ No newline at end of file
+{"AUBAGIO": 0.5762474409362479, "BEXSERO": 3.746596616094324, "CIMZIA": 0.07002986398659, "COMIRNATY": 7.152296111999791, "CYMBALTA": 0.1264035944525195, "ELASOMERAN": 27.80279477065455, "FAMPYRA": 1.472144957492061, "FENTANYL": 0.2243206270201281, "GARDASIL": 1.0007803847720529, "HUMIRA": 1.3359942186806828, "MMRVAXPRO": 0.597122771021198, "MODERNA": 27.996419448719347, "NIMENRIX": 2.48268413298265, "PLEGRIDY": 1.3650878522256056, "PREVENAR": 2.1857287560268137, "RINVOQ": 0.7747387592301658, "ROTATEQ": 0.6050567972993103, "SHINGRIX": 0.7614842593811779, "SPIKEVAX": 4.871591331114365, "TOZINAMERAN": 0.1196612361783814, "TWINRIX": 2.2139374654013158, "VAXZEVRIA": 1.2506226077878182, "ZOSTAVAX": 0.4822389614538609, "null": 0.045527303405885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6102.json
index baff8654f7e..8b77d992ffa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6102.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.2199481677469568, "ADALIMUMAB": 4.87108335621482, "ALIGN": 48.55558979401639, "AMINOSALICYLIC": 24.09811691262469, "AVAMYS": 13.36842235050235, "BUDESONIDE": 16.55266269558192, "COMIRNATY": 2.0204853071541984, "COVID19": 1.0832131564279193, "DESLORATADINE": 2.014524297634052, "FIRDAPSE": 15.399609317702334, "MISOPROSTOL": 19.61731223106112, "PREGABALIN": 7.514113204656563, "SYCREST": 5.346089278198875, "TOZINAMERAN": 2.6093444679716784, "XOLAIR": 1.58911939591942}
\ No newline at end of file
+{"COMIRNATY": 6.853656513622809, "VAXZEVRIA": 0.8312121947180706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6103.json
index 1bf505a2b9e..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6103.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 16.16767691459181, "ASPARAGINASE": 231.63485125133508, "CICLOSPORIN": 13.08529974351386, "CYTARABINE": 73.19461253797118, "SPINRAZA": 51.23897082039803, "SYNAGIS": 40.67945089811968}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6104.json
index 7fe07696a10..6d883bf35df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6104.json
@@ -1 +1 @@
-{"null": 1.9565892807607224}
\ No newline at end of file
+{"ABACAVIR": 161.58609277409082, "ABATACEPT": 1.0555288717720943, "ADALIMUMAB": 4.971955896145842, "AIMOVIG": 1.7096588748808526, "ANAKINRA": 1.727156124606469, "ARAVA": 0.6515257958087662, "AUBAGIO": 0.9536810033870958, "BENLYSTA": 6.030819616535878, "CELLCEPT": 2.473815075086524, "CIMZIA": 0.5841338530643306, "COMIRNATY": 0.2065254314929707, "COSENTYX": 2.9174086878186154, "CYTARABINE": 2.117381157705677, "ENBREL": 8.672808674801876, "FILGRASTIM": 4.148600935072378, "GARDASIL": 1.3729746250045218, "HUMALOG": 0.6468507109852676, "HUMIRA": 7.395190102517019, "IBRANCE": 2.278693209586436, "IMBRUVICA": 11.229011124183092, "JAKAVI": 0.9531136760905818, "JARDIANCE": 0.4246865993771586, "KEYTRUDA": 0.5120673127299383, "KISQALI": 2.7072478251412746, "LANTUS": 0.2136144750142471, "LEFLUNOMIDE": 9.092082399457526, "MEPOLIZUMAB": 0.8299067426770261, "METHOTREXATE": 0.8869022216345438, "NEXAVAR": 0.528827544214687, "NUCALA": 1.0114590477327725, "OCRELIZUMAB": 1.6636597385454122, "ORENCIA": 40.98806332739078, "PEGASYS": 0.5202207178595516, "RINVOQ": 4.402767954120173, "RITUXIMAB": 2.8542280005071445, "ROACTEMRA": 1.7338761774657794, "SHINGRIX": 0.9134045512352276, "SIMPONI": 0.4398372900255624, "SOLIRIS": 1.429930633948391, "SPIKEVAX": 0.2077745108569529, "STELARA": 0.4436397792066989, "SUTENT": 1.5771821467666782, "TOZINAMERAN": 0.6081305565319507, "VAXZEVRIA": 0.0679612826803838, "VFEND": 0.932865046718196, "XELJANZ": 2.999950839941079, "XOLAIR": 1.0802463398507576, "ZOSTAVAX": 1.0055405876588293, "null": 0.3775892209865333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6105.json
index 5678e4eeee7..3890a4e36d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6105.json
@@ -1 +1 @@
-{"AUBAGIO": 1.5859541853365169, "AVANDIA": 1.3668739370251115, "BETAFERON": 2.8328005403394143, "BEXSERO": 3.590123010712093, "BIKTARVY": 1.796846728049546, "BRIDION": 5.215729583354633, "BUPIVACAINE": 6.696687477025248, "DULOXETINE": 1.0254778346631948, "FENTANYL": 2.978347207075359, "GARDASIL": 6.948879687817077, "HIZENTRA": 1.1808508500206447, "HUMALOG": 1.495153102759387, "ISENTRESS": 2.2453383424932265, "JANUMET": 1.0238168764407651, "KESIMPTA": 2.623151903764049, "LANTUS": 1.7844327922064376, "LEVOFLOXACIN": 1.0117488745861758, "LYRICA": 1.7414336251119271, "PLAVIX": 1.226354291473805, "SHINGRIX": 2.8871048689421164, "STALEVO": 4.33061368972657, "TOVIAZ": 1.3260594252136582, "TOZINAMERAN": 2.6046575527240705, "TWINRIX": 4.298732589113557, "VIAGRA": 2.0464886766952586, "null": 1.219363647789523}
\ No newline at end of file
+{"GARDASIL": 12.967196997188552, "null": 0.9589376355324744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6106.json
index cff3c7f1f19..6fc1d1f4fe1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6106.json
@@ -1 +1 @@
-{"null": 1.6456637196320243}
\ No newline at end of file
+{"COMIRNATY": 0.5920295307849959, "null": 0.9044743737771784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6107.json
index 4bb525bac9b..6fdad67cec8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6107.json
@@ -1 +1 @@
-{"AIMOVIG": 568.2280886626462, "BOTULINUM": 217.6383795944915}
\ No newline at end of file
+{"GARDASIL": 44.90256802070202, "SPIKEVAX": 4.245074883332947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6108.json
index ccd93dc19c7..05321e60dbc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6108.json
@@ -1 +1 @@
-{"CELLCEPT": 275.8342741665905}
\ No newline at end of file
+{"null": 0.6048909072855504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6109.json
index a17c698caca..9d4f803c502 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6109.json
@@ -1 +1 @@
-{"AVAMYS": 18.23362315370565, "COMIRNATY": 1.2270152361725877, "COVID19": 1.4549766945912457, "IBRANCE": 1.783156351690495, "NUCALA": 14.623653732306344, "OPSUMIT": 3.702123196102472, "TOZINAMERAN": 3.270418421584146, "VAXZEVRIA": 1.2104733141566426, "XOLAIR": 2.3568381766486555, "ZOSTAVAX": 2.9091104776320784}
\ No newline at end of file
+{"ARAVA": 1.331038005677753, "COMIRNATY": 0.1194749447877224, "HIZENTRA": 33.705963008290006, "RITUXIMAB": 13.352805673393895, "null": 0.8465629333835909}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/611.json
index 79d83f6e43d..411eb991104 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/611.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/611.json
@@ -1 +1 @@
-{"null": 3.304367878880804}
\ No newline at end of file
+{"TOPOTECAN": 1333.8882349122905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6110.json
index 5777924925c..ffa1a4797ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6110.json
@@ -1 +1 @@
-{"IBRANCE": 5.720525304362393, "OPSUMIT": 8.323526228462041, "null": 1.0507779830706734}
\ No newline at end of file
+{"COMIRNATY": 0.2798170852099665, "MEPOLIZUMAB": 48.107009640165856, "null": 1.30258819276114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6111.json
index 64e4c9ecbec..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6111.json
@@ -1 +1 @@
-{"null": 1.659913266071359}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6112.json
index cbaa998ea5f..894b3d75504 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6112.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9245424944342095, "LEVOFLOXACIN": 20.41497334503136, "SPIKEVAX": 1.2330058557220354}
\ No newline at end of file
+{"COMIRNATY": 1.395371779365438, "VAXZEVRIA": 2.268006440704129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6113.json
index 04f83c0802b..af279050a6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6113.json
@@ -1 +1 @@
-{"null": 2.119843710264686}
\ No newline at end of file
+{"null": 0.6830184854001202}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6114.json
index 2613ac8084e..25687a450a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6114.json
@@ -1 +1 @@
-{"ASPARAGINASE": 203.17410242714985}
\ No newline at end of file
+{"ADVAGRAF": 139.76970210997496, "AZATHIOPRINE": 11.778659778291964, "CELLCEPT": 44.03806945953374, "CICLOSPORIN": 28.58602951608526, "MYCOPHENOLATE": 26.11632803558124, "TACROLIMUS": 248.0418648889223, "null": 1.7848471653974085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6115.json
index 08c721e38a1..0269e265176 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6115.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 32.90743054345186, "KEYTRUDA": 12.313563280528632}
\ No newline at end of file
+{"ADVAGRAF": 203.08749041628212, "BASILIXIMAB": 27.704005804894063, "CELLCEPT": 18.322159098951992, "CICLOSPORIN": 60.54991635083719, "ENVARSUS": 292.806821929976, "EVEROLIMUS": 27.509769063503462, "KALETRA": 13.960367470115209, "MYCOPHENOLATE": 43.54833528534023, "RAPAMUNE": 77.75198356218219, "TACROLIMUS": 264.6432124536741, "VFEND": 17.888887628932846, "VORICONAZOLE": 24.32719721298393, "null": 1.0294391881631877}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6116.json
index f4d2da3a10a..7b009a4a58f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6116.json
@@ -1 +1 @@
-{"ABILIFY": 3.6071599831000976, "AERIUS": 4.265530906808739, "ANTIBIOTICS": 26.71934929252364, "ARIPIPRAZOLE": 8.105322564801313, "ATAZANAVIR": 99.48050623294212, "BIKTARVY": 2.364334584402473, "BORTEZOMIB": 7.083730416430863, "BRINTELLIX": 1.267905343131274, "BRIVIACT": 5.753530859635969, "BUPRENORPHINE": 2.952757758044624, "CHAMPIX": 25.11822714408249, "COMTAN": 7.937459235975657, "CYMBALTA": 3.960282633794132, "DOXORUBICIN": 1.9563828183862295, "ENFUVIRTIDE": 49.72140767682633, "FYCOMPA": 5.685450323534483, "HARVONI": 2.074809780275474, "INTRONA": 3.3343337518119984, "KEPPRA": 4.226306789099626, "LATUDA": 13.471220864343618, "LEVETIRACETAM": 3.360779403643656, "LEVODOPA": 12.369932604489309, "LEVOFLOXACIN": 1.0905512853390409, "OLANZAPINE": 5.36353819543423, "PEGASYS": 3.679762711832305, "PEGINTRON": 4.397214970717138, "RIBAVIRIN": 2.147162603587857, "RISPERIDONE": 9.838709216430772, "SIFROL": 4.578169682881997, "STALEVO": 5.749322435225319, "SUBOXONE": 7.139983385440125, "TAMIFLU": 2.5087993514651235, "VARENICLINE": 11.530650983975736, "VIMPAT": 2.999011153345502, "XYREM": 9.683113198735764, "ZYPREXA": 4.850032534517471, "null": 1.907974838732796}
\ No newline at end of file
+{"AFINITOR": 1.2484410962596058, "AIMOVIG": 1.9773930452564192, "ALEMTUZUMAB": 8.32309731089317, "ARAVA": 0.948133753357809, "AUBAGIO": 2.576172975982268, "AZATHIOPRINE": 5.2497113642295, "BENLYSTA": 10.19676707680172, "CAPECITABINE": 6.85745763395408, "CELLCEPT": 3.998468686130389, "CICLOSPORIN": 7.28337362857909, "CIMZIA": 3.0283457418376774, "COMIRNATY": 0.1122040645255183, "COSENTYX": 4.438186271884652, "CYTARABINE": 3.823556269592133, "DEXAMETHASONE": 2.87460627684992, "ENBREL": 2.353486226874941, "ENTYVIO": 2.516292671338029, "ERIBULIN": 103.42939245317604, "HUMIRA": 4.637544011122462, "IBRANCE": 5.212237334347816, "JAKAVI": 7.456102833237416, "LEMTRADA": 4.518276277774243, "METHOTREXATE": 7.184653633621811, "MYCOPHENOLATE": 6.88959264136623, "NPLATE": 5.897940324943267, "NUCALA": 1.4865778841810522, "PEGASYS": 1.0218604700133078, "PEGINTRON": 1.0850744777348669, "RINVOQ": 8.373648942701143, "RITUXIMAB": 5.791066233533313, "ROACTEMRA": 3.629354120766268, "SOLIRIS": 6.51870339049537, "SPIKEVAX": 0.1171708366115638, "STELARA": 2.34499971485353, "SUTENT": 1.303896503621205, "TOZINAMERAN": 0.3844365947485366, "VAXZEVRIA": 0.0453803472650075, "XELJANZ": 11.31408529049527, "XOLAIR": 1.1115536688403131, "null": 0.5091641625182257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6117.json
index 3e9b2a59789..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6117.json
@@ -1 +1 @@
-{"null": 1.5682485806606292}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6118.json
index cd41d320600..eb058822295 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6118.json
@@ -1 +1 @@
-{"AUBAGIO": 4.2561447722440535, "BENZODIAZEPINES": 122.0268062117308, "BETAFERON": 13.538559077179602, "CICLOSPORIN": 2.063595664184878, "FAMPYRA": 8.25838688906546, "GARDASIL": 60.87283161650386, "LEMTRADA": 11.096144810247372, "SUFENTANIL": 15.96645380539012}
\ No newline at end of file
+{"AUBAGIO": 2.8149111642793065, "BRINTELLIX": 1.6434523892789468, "BUDESONIDE": 1.542290312548361, "BUMETANIDE": 29.19821471069218, "BUPRENORPHINE": 8.353738699388481, "CHAMPIX": 9.715193054552389, "COMIRNATY": 0.4873750678918646, "CYMBALTA": 1.2225676301376427, "FENTANYL": 4.003419598186716, "GARDASIL": 0.4882077120597998, "KEPPRA": 1.6929731238639842, "LANTUS": 0.9723993077146168, "LYRICA": 9.840583200536145, "PEGASYS": 0.412470655242963, "PREGABALIN": 3.145483563579853, "SHINGRIX": 1.6289424898380822, "SPIKEVAX": 0.7612618660772639, "SUBOXONE": 9.260959615908895, "SUTENT": 0.4768963903207207, "TOZINAMERAN": 0.9024851982512418, "VAXZEVRIA": 0.2015771349723358, "XELJANZ": 0.9777809418666024, "null": 2.0796691168299617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6119.json
index 4585761d2a4..46ca8d103ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6119.json
@@ -1 +1 @@
-{"LEVODOPA": 980.963496440671, "null": 1.125430266136171}
\ No newline at end of file
+{"ZOSTAVAX": 87.25593876814074, "ZYPREXA": 9.472145022956637, "null": 0.933150434971299}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/612.json
index 3edb2fdb676..d0da08dcfd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/612.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/612.json
@@ -1 +1 @@
-{"ALDARA": 364.0892757176776, "BUPRENORPHINE": 7.765091028739306, "QUTENZA": 70.4415342237246, "null": 6.472640969371964}
\ No newline at end of file
+{"DABRAFENIB": 1006.3657503455536, "MEKINIST": 107.34786695611486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6120.json
index 83d6cdffc5c..73447695613 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6120.json
@@ -1 +1 @@
-{"JARDIANCE": 104.49675120507555}
\ No newline at end of file
+{"AIMOVIG": 6.574060561151203, "APIDRA": 1.723234144037513, "ARAVA": 1.2288015588310033, "BENLYSTA": 2.748325754845046, "BYDUREON": 6.723533294869586, "BYETTA": 10.259747547109882, "CELLCEPT": 2.027509199105987, "CIMZIA": 0.5586348475147495, "CLOPIDOGREL": 1.1020213176726552, "COMIRNATY": 0.0957677618244991, "CYMBALTA": 0.8352379979448527, "ENBREL": 0.8569675087804197, "FENTANYL": 1.4504241465914258, "GARDASIL": 5.598179826764711, "HUMALOG": 6.906629360592932, "INSULIN": 3.4940164994538687, "JANUMET": 3.1631747258969667, "JANUVIA": 3.028640280251992, "JARDIANCE": 1.203249932348715, "LANTUS": 2.2462797152407137, "LYRICA": 1.823126226805089, "METHOTREXATE": 1.5389516076077303, "OPSUMIT": 1.0598917230736593, "OPTIMARK": 2.3389550206460554, "OZEMPIC": 24.94757765689803, "RYBELSUS": 31.846828417034583, "SAXENDA": 9.82577811679446, "SPIKEVAX": 0.0399047122117866, "SUTENT": 0.302903673592886, "TOZINAMERAN": 0.4985297256388747, "TRESIBA": 13.909185529945471, "TRULICITY": 22.36237884837358, "VAXZEVRIA": 0.0503626698256294, "VICTOZA": 20.079460769484044, "XELJANZ": 1.2783993723813, "XOLAIR": 1.686897415393437, "ZYPREXA": 1.00375447472738, "null": 1.220733270382236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6121.json
index 6ffce909b8f..665acb01fe4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6121.json
@@ -1 +1 @@
-{"BUPIVACAINE": 25.22604234464008, "CLOPIDOGREL": 5.954199184311182, "CYTARABINE": 3.64482324948938, "DEXAMETHASONE": 2.556019997829242, "EFAVIRENZ": 10.0263513272291, "ELIQUIS": 2.450934675190487, "ENOXAPARIN": 6.782309096396426, "FENTANYL": 6.703989195356158, "GARDASIL": 2.8724471925193984, "LEVETIRACETAM": 6.776141061300896, "PEGINTRON": 1.2803814549962538, "PLAVIX": 1.1241075867735015, "SUTENT": 1.2685760674970514, "VIAGRA": 4.369812844927618, "null": 1.5883535455549458}
\ No newline at end of file
+{"ABACAVIR": 0.1980714485542784, "ABATACEPT": 26.347293509938613, "ABILIFY": 0.4361693002314768, "ACETAMINOPHEN": 43.76835572255833, "ADALIMUMAB": 12.112984835410993, "AFINITOR": 0.4318595161285773, "AIMOVIG": 0.691980964617186, "ANAKINRA": 2.674021417213229, "APIDRA": 0.6166960212163204, "APREMILAST": 1.5184938890522863, "APREPITANT": 50.58495734397461, "ARAVA": 9.776188047234552, "ATRIPLA": 0.1034935678332625, "AUBAGIO": 0.7506333055379765, "AVASTIN": 3.2749468826524013, "AZATHIOPRINE": 0.6473488522194067, "BENLYSTA": 0.9653962721234536, "BETAFERON": 1.3043235022031197, "BEVACIZUMAB": 0.9171409299607036, "BONVIVA": 3.9670913186831194, "BRILIQUE": 0.5357221989996627, "CABOMETYX": 4.975232848015149, "CELLCEPT": 0.8056183336263416, "CERTOLIZUMAB": 11.919250675325646, "CHLORHEXIDINE": 67.00948521742104, "CICLOSPORIN": 1.189442046239793, "CIMZIA": 23.843841898852624, "CLOPIDOGREL": 0.2147241500725149, "COMIRNATY": 0.076562335088927, "COSENTYX": 1.384662191020672, "CUBICIN": 1.3177226730418576, "CYMBALTA": 0.4463972515133179, "CYTARABINE": 0.4464572796413775, "DEXAMETHASONE": 0.2522556179063671, "DOXORUBICIN": 0.952637015425204, "ELIQUIS": 0.8756847782892353, "ENBREL": 2.777814458372898, "ENTYVIO": 1.145331869120488, "EVISTA": 1.645004179234352, "FASLODEX": 0.584305780369697, "FORSTEO": 0.9999924774918488, "GARDASIL": 0.2504819520563352, "HUMALOG": 2.2494534851634427, "HUMIRA": 1.2065204744817275, "IBRANCE": 1.4621263250248366, "INLYTA": 2.0935331175948053, "JAKAVI": 1.041709066111596, "JANUMET": 0.7149103646135815, "JARDIANCE": 1.025828943067203, "KEPPRA": 0.2890446028717386, "KEYTRUDA": 0.4285440183302494, "LANTUS": 0.853239706840801, "LEFLUNOMIDE": 2.7718243471613344, "LENVIMA": 3.640410868017765, "LIRAGLUTIDE": 3.824057503771781, "LIXIANA": 1.4264292961155274, "LYRICA": 0.3061311806986844, "MEKINIST": 0.5195675176103204, "METHOTREXATE": 1.1646592349351408, "MYCOPHENOLATE": 2.2702477276897004, "NEXAVAR": 1.1416171238912525, "OFEV": 1.7764639624438587, "OMALIZUMAB": 0.6077324522513398, "OPTIMARK": 0.7989624795747534, "PEGASYS": 0.2778769065518931, "PEGINTRON": 0.5176008058369834, "PLAVIX": 0.9969725720309892, "PROLIA": 7.726653681938115, "RAPAMUNE": 7.295174682214194, "REMICADE": 1.3759738637642838, "RINVOQ": 1.0280868053966372, "RITUXIMAB": 3.04940419178873, "ROACTEMRA": 2.662479823241335, "SIMPONI": 1.1457890852048045, "SPIKEVAX": 0.060024722460471, "STELARA": 0.3826591361323415, "STIVARGA": 0.8459785761519323, "SUBOXONE": 0.2343534898425195, "SUTENT": 2.7867021470032425, "TASIGNA": 0.4761322820965958, "TOZINAMERAN": 0.0558689051676666, "TREMFYA": 0.777620439772739, "VAXZEVRIA": 0.0283946390883745, "VOTRIENT": 2.3266746471993858, "XELJANZ": 2.265318330541839, "XOLAIR": 0.3065230948819243, "ZOMETA": 5.11357132893882, "ZOSTAVAX": 0.2914188132049277, "ZYPREXA": 0.3650773582841841, "null": 0.3250685808298029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6122.json
index 091346625d5..ebcc0430d60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6122.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3961135368649382}
\ No newline at end of file
+{"null": 0.5639274422831586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6123.json
index 1ca49772616..42aa9a2190c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6123.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 31.775020412595183, "XYREM": 102.17006879388096, "null": 1.7424013740275064}
\ No newline at end of file
+{"ABILIFY": 1.2083612591982746, "ACLIDINIUM": 11.917003816073244, "ADALIMUMAB": 8.911137040425606, "AMINOSALICYLIC": 2.986795202043897, "ANAKINRA": 12.896909009287018, "ARAVA": 0.4187659291802477, "ATRIPLA": 0.1354076125124073, "AUBAGIO": 3.098447620031068, "BUDESONIDE": 3.32650437557122, "BUPRENORPHINE": 4.112522967296689, "CAPSAICIN": 236.55201943217665, "COMIRNATY": 1.259387168197162, "DULOXETINE": 22.16618899542657, "ENTYVIO": 4.275595788849079, "FENTANYL": 1.042672281798441, "HUMIRA": 7.132041644020717, "IBRANCE": 0.5668055266960806, "METHOTREXATE": 1.0863197752714409, "NUCALA": 2.710835760957862, "OLANZAPINE": 1.2333083198472632, "PLAVIX": 0.875240535500563, "SHINGRIX": 0.9459813010978628, "SPIKEVAX": 0.6912077127752557, "TOZINAMERAN": 0.8924259264071595, "VAXZEVRIA": 0.2705590290347857, "XELJANZ": 3.1673472606735062, "null": 0.8413018692074564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6124.json
index 830d2d55b77..101b4b0d9aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6124.json
@@ -1 +1 @@
-{"ADALIMUMAB": 11.73022432182549, "MIMPARA": 147.73537481203763, "null": 1.261893216734958}
\ No newline at end of file
+{"COMIRNATY": 0.3199162017949845, "VAXZEVRIA": 0.4546953253685801, "null": 2.661020541391055}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6125.json
index 1612736e4f4..8331b9195e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6125.json
@@ -1 +1 @@
-{"null": 2.043655518311099}
\ No newline at end of file
+{"ABATACEPT": 0.736036277387519, "ABILIFY": 1.0909169684643976, "ADALIMUMAB": 2.082007377954231, "AIMOVIG": 0.2353936746120198, "ALISKIREN": 9.104653379261858, "ANAKINRA": 4.581584463408498, "ARAVA": 1.7241936389342931, "ATRIPLA": 1.3770245988875538, "AUBAGIO": 1.054579043330691, "BENLYSTA": 1.1449191882931826, "BIKTARVY": 0.801265278706138, "BRINTELLIX": 0.6747257854899016, "BUDESONIDE": 0.261188695674938, "BUPRENORPHINE": 0.7490217057049239, "CAPSAICIN": 64.17147643935897, "CHAMPIX": 1.823866029686633, "CIMZIA": 1.159514523940852, "COMIRNATY": 1.8532533475205464, "CYMBALTA": 0.4559320538869806, "ENBREL": 3.854267387592981, "FENTANYL": 1.5126552493352745, "GALAFOLD": 5.213511559014525, "GARDASIL": 3.219887370171268, "HIZENTRA": 0.7198625270212603, "HUMIRA": 2.789202680415823, "IBRANCE": 0.1363734700382083, "IBUPROFEN": 0.3513084957997814, "JANUVIA": 0.3000884241855841, "KEPPRA": 0.9234879914587836, "LANTUS": 0.3052481039905045, "LEVOFLOXACIN": 0.7691848306386335, "LYRICA": 1.9853976409521357, "METHOTREXATE": 0.5513108871202731, "OLANZAPINE": 0.2528890258061947, "PEGASYS": 0.3242372671102191, "PEGINTRON": 0.5801896016681809, "PLAVIX": 0.4395842297778419, "SHINGRIX": 1.7570084525390022, "SPIKEVAX": 2.0092771518911525, "STRIBILD": 2.0435730049528598, "SUBOXONE": 0.6304590889888391, "TOZINAMERAN": 0.9452421342027592, "TRUVADA": 0.8488737849437347, "TWINRIX": 2.9696472512372623, "VAXZEVRIA": 1.318965742800634, "VIAGRA": 0.9335690942476788, "XELJANZ": 1.290404556685234, "null": 0.7564530266480273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6126.json
index 413a6243062..ea63aca038a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6126.json
@@ -1 +1 @@
-{"null": 1.4481593619296391}
\ No newline at end of file
+{"ABILIFY": 22.860830801950087, "CHAMPIX": 10.22638179235868, "COMIRNATY": 0.1204352903853262, "CYMBALTA": 2.932554856385156, "KEPPRA": 6.788737708419065, "PEGASYS": 3.646684457617973, "SUTENT": 1.5931410709706466, "null": 2.1050560329877936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6127.json
index 724873a75d6..103012a7c01 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6127.json
@@ -1 +1 @@
-{"MIMPARA": 487.32319843541393, "null": 1.97621069506955}
\ No newline at end of file
+{"COMIRNATY": 1.3913697540835566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6128.json
index 59397b12a47..7235cffca44 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6128.json
@@ -1 +1 @@
-{"MIMPARA": 819.8834597316322}
\ No newline at end of file
+{"ZYPREXA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6129.json
index 73844ab6af5..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6129.json
@@ -1 +1 @@
-{"ADALIMUMAB": 5.252258124854462, "MIMPARA": 988.230776727609}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/613.json
index e1abafb4bb4..ab84ba4a0b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/613.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/613.json
@@ -1 +1 @@
-{"null": 1.3105706451927457}
\ No newline at end of file
+{"IRINOTECAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6130.json
index 7406afa5d33..c1245ace4f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6130.json
@@ -1 +1 @@
-{"null": 7.510767283920724}
\ No newline at end of file
+{"ABACAVIR": 8.154383034073085, "BUPRENORPHINE": 6.110437616374979, "COMIRNATY": 0.4561826501631051, "COSENTYX": 4.761869660084068, "GARDASIL": 2.4300937239117792, "RINVOQ": 18.77673497566645, "SPIKEVAX": 0.3012399226191368, "STELARA": 3.4791044953535666, "TOZINAMERAN": 0.7604486832824897, "VAXZEVRIA": 0.2248490913473856, "ZOSTAVAX": 6.123908470839947, "null": 0.82001804931313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6131.json
index 84e640e77d6..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6131.json
@@ -1 +1 @@
-{"null": 1.017980813242261}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6132.json
index ee619261f6e..de1447dad91 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6132.json
@@ -1 +1 @@
-{"CASPOFUNGIN": 407.845926029848, "null": 5.203844953381612}
\ No newline at end of file
+{"PANTOPRAZOLE": 213.64853114502495, "null": 0.5703274743427723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6133.json
index 40e36b9160e..b815aef079a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6133.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 3.688983128231283, "COMIRNATY": 1.94039833975906, "FENTANYL": 1.1275780797628547, "GARDASIL": 4.392160465170734, "METHOTREXATE": 1.4893114133823282, "PEGINTRON": 1.0027692452752617, "SHINGRIX": 2.0918397076855904, "TWINRIX": 9.11074287435665, "VAXZEVRIA": 1.93455359975412, "null": 1.1748538349800008}
\ No newline at end of file
+{"BUPIVACAINE": 264.4196866497728, "LINACLOTIDE": 6588.100700844751, "null": 1.2111323647658876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6134.json
index 17e3b24c710..e8e1f6b8d2a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6134.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0110830246357052}
\ No newline at end of file
+{"IRON": 222.6172074230019, "KEPPRA": 15.36318762310279, "OCEAN": 4167.916707069352, "PANTOPRAZOLE": 101.4906427848626, "TOVIAZ": 169.6004886034721, "null": 0.5283813682031073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6135.json
index 6d0aed9dfe1..58537b8fa73 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6135.json
@@ -1 +1 @@
-{"ABILIFY": 2.606553734423559, "APIDRA": 1.0250092597629508, "ARIPIPRAZOLE": 1.084746609996004, "AZILECT": 33.47523438910083, "BYDUREON": 2.945994895410787, "CARBIDOPA": 102.86727421896629, "CEREZYME": 365.8581108859343, "COMTAN": 141.7651698625537, "CYMBALTA": 1.105541067520699, "ELIQUIS": 1.9259890180186248, "ENTACAPONE": 89.26674060586625, "EVENITY": 2.926948208048838, "EXFORGE": 1.577990648036634, "FORSTEO": 2.9627899025069766, "HUMALOG": 3.8719616118628535, "IBRANCE": 1.0830436828564125, "JANUVIA": 1.8818964673302252, "LANTUS": 3.070154399833378, "LATUDA": 3.670973563437508, "LEVEMIR": 2.080299468795502, "LEVODOPA": 47.02115758391009, "LYRICA": 1.3780536350685877, "NEUPRO": 37.36175526731196, "OLANZAPINE": 1.5852936244699103, "PANTOPRAZOLE": 4.848278624168591, "RANOLAZINE": 8.306014249681576, "SIFROL": 15.664549898185424, "SIMPONI": 1.3873841715391857, "STALEVO": 196.40166614224387, "STELARA": 1.813841121734242, "TASIGNA": 1.050447010144292, "TOVIAZ": 11.154932242831832, "TRULICITY": 1.081776314692624, "VIAGRA": 4.699312148714355, "XELJANZ": 2.0725179632364497, "XTANDI": 1.5704144656354713, "ZOSTAVAX": 1.0648527469829037, "ZYPREXA": 2.54374095667948, "null": 1.5526819746519245}
\ No newline at end of file
+{"PANTOPRAZOLE": 112.80501957193523, "null": 1.6158285616134158}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6136.json
index 0a6fffecc3c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6136.json
@@ -1 +1 @@
-{"CARBIDOPA": 2848.169582419294}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6137.json
index a6dc8647ba9..276a796ed96 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6137.json
@@ -1 +1 @@
-{"STALEVO": 840.9120212576136, "null": 1.5177451042929735}
\ No newline at end of file
+{"BUPIVACAINE": 66.2278197104629, "CYMBALTA": 5.43197385065716, "FENTANYL": 11.503321612699366, "KEPPRA": 20.60837105032082, "LINACLOTIDE": 2632.407900761736, "MIRABEGRON": 367.6303099999968, "null": 1.2765817837354347}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6138.json
index b23416344a2..816fee5a6d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6138.json
@@ -1 +1 @@
-{"ENTACAPONE": 195.87889138105592, "LEVODOPA": 161.27818397582072, "OLANZAPINE": 10.39507516048998, "ZYPREXA": 7.115324045415322, "null": 2.2705447323482426}
\ No newline at end of file
+{"PLAVIX": 66.66762345310205}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6139.json
index 5979e2ded76..f8cd22aa2ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6139.json
@@ -1 +1 @@
-{"CARBIDOPA": 288.99640557645824, "OLANZAPINE": 19.91414013769362}
\ No newline at end of file
+{"null": 2.52965674176222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/614.json
index ba8cde63e05..40e113c5841 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/614.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/614.json
@@ -1 +1 @@
-{"ALDARA": 63.88590868536174, "BUPRENORPHINE": 6.1062402543127945, "EVRA": 60.05365519160141, "OPSUMIT": 2.91534735939021, "null": 15.773994281436265}
\ No newline at end of file
+{"null": 0.3912703338460954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6140.json
index 6031cf35e00..9249c259799 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6140.json
@@ -1 +1 @@
-{"ABILIFY": 18.565155826930127, "ARIPIPRAZOLE": 19.476646667807582, "ATAZANAVIR": 2.666821968980529, "AZILECT": 21.3905529021994, "CARBIDOPA": 13.175958269772584, "CARIPRAZINE": 88.298763168657, "COMTAN": 7.084402574685902, "CYMBALTA": 1.1136417677360988, "ENTACAPONE": 25.524049144938555, "INVEGA": 21.79121037476481, "KEPPRA": 1.45318949456275, "LACOSAMIDE": 2.7560485677460216, "LATUDA": 10.460422764586962, "LEVETIRACETAM": 1.2773221158633852, "LEVODOPA": 38.09030227816618, "LOXAPINE": 34.10754488140372, "NEUPRO": 49.79497931617493, "OLANZAPINE": 25.270518300614523, "PEGINTERFERON": 1.9982805262957983, "PEGINTRON": 1.1369744708022111, "PREGABALIN": 4.160283368146442, "PROPRANOLOL": 5.280013938476501, "REAGILA": 25.37826357570688, "RISPERIDONE": 19.074003955242866, "SIFROL": 12.737749659104246, "SPIRONOLACTONE": 9.596792245219186, "STALEVO": 7.755478468608146, "SYCREST": 42.65624719921861, "ZYPREXA": 15.681670210029065, "null": 3.218917769417358}
\ No newline at end of file
+{"ELIQUIS": 15.20462593790742, "null": 1.0022048488299071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6141.json
index cadc59ca373..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6141.json
@@ -1 +1 @@
-{"CARBIDOPA": 967.5378719692492}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6142.json
index 01b0ffe3e3e..35e821b6eb8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6142.json
@@ -1 +1 @@
-{"AFATINIB": 245.1656015327333, "AFINITOR": 5.100274896045671, "ALEMTUZUMAB": 8.34648148828121, "AVASTIN": 4.377019549516368, "BEVACIZUMAB": 16.433894527846267, "BRAFTOVI": 9.72228291733152, "CETUXIMAB": 34.87132313773825, "COSENTYX": 1.8474901219402688, "CRIXIVAN": 31.694505564086292, "CYTARABINE": 4.426790638793492, "DOCETAXEL": 5.435922286220248, "ERBITUX": 127.35631535512138, "GEFITINIB": 87.68899063871469, "HERCEPTIN": 8.513438932237628, "IRESSA": 110.48531786560513, "IRINOTECAN": 25.965644440670207, "KEYTRUDA": 1.2245979602895736, "MEKINIST": 3.3856004634457206, "OSIMERTINIB": 101.30965749809664, "PANITUMUMAB": 236.9122316971992, "ROACTEMRA": 4.034797646177136, "STIVARGA": 2.908198723791648, "TAGRISSO": 140.35659557675618, "TRAMETINIB": 142.97919276519008, "VECTIBIX": 352.93183242823807}
\ No newline at end of file
+{"BUPIVACAINE": 49.869817228685655, "FENTANYL": 7.808487320868249, "IRON": 82.1613590858906, "KEPPRA": 15.95143265341054, "MELATONIN": 54.31913211775271, "TOVIAZ": 59.44726748539614, "null": 1.5144212101788888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6143.json
index ebe48bc5d3d..e4f4b5bc531 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6143.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.6585521834457106, "AVAMYS": 1.1953400366525997, "BRINTELLIX": 1.8041439003175117, "CHAMPIX": 1.4514343393532136, "COMIRNATY": 2.152650668184402, "COVID19": 1.4154847800867538, "GARDASIL": 1.4143411624587932, "MICARDIS": 1.2377269844132937, "PEGINTRON": 1.9458685313101511, "SAXENDA": 1.052110179201088, "SPIKEVAX": 1.3072822510829103, "TOZINAMERAN": 1.662665349242617, "TRULICITY": 1.5070283248355516, "VAXZEVRIA": 1.3295153829988235}
\ No newline at end of file
+{"PANTOPRAZOLE": 203.6820915811512, "null": 0.4211122573965482}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6144.json
index e78bdce14f9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6144.json
@@ -1 +1 @@
-{"null": 1.4641793956652778}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6145.json
index 55db53dc748..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6145.json
@@ -1 +1 @@
-{"KEYTRUDA": 1.415942859228313, "MMRVAXPRO": 82.10370106574, "null": 2.4518449042620136}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6146.json
index 13d2e274a0b..0067007e04b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6146.json
@@ -1 +1 @@
-{"AVAMYS": 64.67500455446003, "MMRVAXPRO": 34.78395360307713, "null": 1.6939508984165672}
\ No newline at end of file
+{"BUPIVACAINE": 158.36213007900008, "COMIRNATY": 0.3329082417888463, "FENTANYL": 12.444086113608249, "SPIKEVAX": 0.413912218749784, "null": 1.5829180668206957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6147.json
index 12837924f63..c437be4e808 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6147.json
@@ -1 +1 @@
-{"COMIRNATY": 1.084991036399349}
\ No newline at end of file
+{"PANTOPRAZOLE": 453.4762013104217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6148.json
index 6d2525e73f2..760e78ea8c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6148.json
@@ -1 +1 @@
-{"COVID19": 5.064751622687733, "EFAVIRENZ": 586.0335193128805}
\ No newline at end of file
+{"null": 4.702219858979559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6149.json
index 16bcb7906af..dd161db73cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6149.json
@@ -1 +1 @@
-{"CICLOSPORIN": 11.089954322061155, "SOLIRIS": 341.02619745721444}
\ No newline at end of file
+{"null": 1.5608023183884372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/615.json
index 124d3d2a195..0a9e64f7fea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/615.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/615.json
@@ -1 +1 @@
-{"null": 4.617604539187664}
\ No newline at end of file
+{"BEVACIZUMAB": 79.36471230496774, "null": 0.3380527281218915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6150.json
index 22514f5ccc8..258c9b07c9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6150.json
@@ -1 +1 @@
-{"null": 1.070559733320756}
\ No newline at end of file
+{"AVONEX": 705.692691379214, "CYMBALTA": 11.140134853862186, "KEPPRA": 20.37471901130056, "null": 0.6224259699253132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6151.json
index ea8de872d55..1079b51874c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6151.json
@@ -1 +1 @@
-{"null": 2.844207717923794}
\ No newline at end of file
+{"YONDELIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6152.json
index b8aeaf164b8..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6152.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 1.609770058556152, "ARANESP": 1.583616861440113, "ARIPIPRAZOLE": 1.2131034238465344, "ASPARAGINASE": 7.125067755412741, "AUBAGIO": 1.205570685291245, "BRIVARACETAM": 13.619399023248173, "BRIVIACT": 43.44448147852698, "CICLOSPORIN": 3.144065161274676, "DEXAMETHASONE": 4.320960673856503, "FAMPYRA": 3.046019093501283, "FENTANYL": 1.8490898512690703, "FYCOMPA": 23.135567874753814, "GARDASIL": 1.5494722129249474, "IBUPROFEN": 1.3631943847733203, "INFANRIX": 8.957637840918013, "KEPPRA": 36.55949668069951, "LACOSAMIDE": 94.6800849143202, "LEVETIRACETAM": 46.1992944010548, "LYRICA": 2.0611289854331467, "MIDAZOLAM": 9.50264505072604, "PERAMPANEL": 45.44369259789571, "TAMIFLU": 1.3277173634864818, "VIMPAT": 22.32943163219125, "XTANDI": 1.019418768106702, "ZONISAMIDE": 26.277264727374625, "null": 1.0607400469482564}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6153.json
index d2fbd0a802d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6153.json
@@ -1 +1 @@
-{"BRIVARACETAM": 610.7360466308605, "KEPPRA": 19.223293066564263, "LACOSAMIDE": 70.69648296726015, "LEVETIRACETAM": 37.36526787412522, "VIMPAT": 47.58366789819265}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6154.json
index 140d295886c..1bc872927b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6154.json
@@ -1 +1 @@
-{"ATRIPLA": 2.734755129734826, "TRUVADA": 4.124631218771299, "null": 3.9906472906582495}
\ No newline at end of file
+{"FIRDAPSE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6155.json
index 669501723e2..121086353f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6155.json
@@ -1 +1 @@
-{"ARANESP": 23.237744443252264, "CELLCEPT": 17.338062751951334, "CICLOSPORIN": 23.78075284200802, "MYCOPHENOLATE": 83.11189606042485}
\ No newline at end of file
+{"AVANDAMET": 72.10628156499364, "AVANDIA": 67.76721455366767, "COMIRNATY": 0.10341527563814, "ENTRESTO": 7.521236884866854, "GALAFOLD": 95.1580602402994, "SILDENAFIL": 25.739785855873027, "null": 1.1769790898109749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6156.json
index ce29bedde71..65b0fa474f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6156.json
@@ -1 +1 @@
-{"CELLCEPT": 68.17961602160781}
\ No newline at end of file
+{"null": 1.7424497548446465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6157.json
index e2998e36555..dad70a3c288 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6157.json
@@ -1 +1 @@
-{"null": 1.609848241428752}
\ No newline at end of file
+{"null": 5.334958498674236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6158.json
index d872febe280..5ffc191948e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6158.json
@@ -1 +1 @@
-{"null": 2.6974128087585774}
\ No newline at end of file
+{"null": 1.9308669274594548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6159.json
index 6fb1e2d036b..4e8ad818b63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6159.json
@@ -1 +1 @@
-{"ATRIPLA": 10.587732344437724, "ELIQUIS": 1.653741001201637, "EVISTA": 28.396294877641424, "FORSTEO": 13.04652586452305, "HUMALOG": 2.8024408704587014, "KALETRA": 12.765750670362692, "STRIBILD": 4.065729447325782, "TRUVADA": 6.244898346236188, "XELJANZ": 4.412541845948415, "null": 1.0013304432120635}
\ No newline at end of file
+{"ABILIFY": 16.74170240924194, "AZILECT": 64.74050840141537, "CARBIDOPA": 86.366077507589, "CYMBALTA": 1.238036153242824, "ENTACAPONE": 92.71688525003526, "KEPPRA": 1.888048916035297, "LEVODOPA": 257.6020699368528, "NEUPRO": 196.8637368244121, "RASAGILINE": 882.9245621992858, "ROTIGOTINE": 1163.3644995102547, "SIFROL": 477.8563340275925, "STALEVO": 33.91390444203331, "null": 1.6705653857623926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/616.json
index 41c04f4437d..5f76ea52346 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/616.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/616.json
@@ -1 +1 @@
-{"COMIRNATY": 11.401112698468564, "SPIKEVAX": 1.7358780501614377}
\ No newline at end of file
+{"OCTREOTIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6160.json
index e958f50c97b..6b5efd6e29f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6160.json
@@ -1 +1 @@
-{"ATRIPLA": 3.1221547288735256}
\ No newline at end of file
+{"ABILIFY": 12.266971286682733, "ARIPIPRAZOLE": 5.237387687559451, "BRINTELLIX": 5.061884232596684, "BUDESONIDE": 2.3152326186119097, "CHAMPIX": 7.822267655108584, "CYMBALTA": 2.909326704895814, "ENTACAPONE": 51.4465266678604, "KAFTRIO": 16.25844733772006, "KEPPRA": 4.837347029700292, "LATUDA": 12.267298597575476, "LEVETIRACETAM": 10.038878560968842, "MELATONIN": 19.39901206726316, "OLANZAPINE": 8.135494969940602, "null": 3.0770950663554606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6161.json
index 4d4c59757d2..22da8098083 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6161.json
@@ -1 +1 @@
-{"BRIVARACETAM": 53.23991995776781, "COMBIVIR": 8.213741271929631, "DEXAMETHASONE": 2.6984252007597034, "EPIVIR": 9.991896921848657, "ESOMEPRAZOLE": 11.78958046933987, "IBUPROFEN": 7.5524229690021, "KALETRA": 4.919850697279562, "KEPPRA": 4.9851020982742655, "LEVETIRACETAM": 2.964952658625009, "NORVIR": 14.95502870289387, "null": 7.291347057694717}
\ No newline at end of file
+{"ABILIFY": 8.925122740638542, "ANORO": 10.106397769075995, "BRIVIACT": 25.330867579726952, "CIMZIA": 10.508868076719644, "ELIQUIS": 2.6167691652960934, "FASENRA": 15.354684236328776, "JANUMET": 8.275650332508778, "JANUVIA": 13.834756738896036, "KEPPRA": 2.1437875420509758, "KEYTRUDA": 2.422859994405677, "TRELEGY": 30.966167299473625, "VIMPAT": 15.869477421325698, "null": 2.594208040646259}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6162.json
index b2efebd1e31..601c0c8268b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6162.json
@@ -1 +1 @@
-{"null": 4.826380696809855}
\ No newline at end of file
+{"null": 1.4245068139663926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6163.json
index 3e2f4435b73..fa80be96fc8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6163.json
@@ -1 +1 @@
-{"KEPPRA": 26.518275989902943}
\ No newline at end of file
+{"BUPRENORPHINE": 22.17612625350558, "CLOPIDOGREL": 2.093661747231624, "FENTANYL": 17.04538342504066, "IBUPROFEN": 5.982020252083279, "PREGABALIN": 16.664847894805806, "SUBOXONE": 8.553122753013692, "SUFENTANIL": 40.11323721734267, "VAXZEVRIA": 0.5767735445846623, "null": 4.132291840392794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6164.json
index 9be6e356a03..7fa58908a46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6164.json
@@ -1 +1 @@
-{"COSENTYX": 21.274910866504865, "SIMPONI": 13.403767429590582, "STELARA": 19.712343347763444, "SUBOXONE": 14.783800191642344, "TASIGNA": 15.186235814275127, "TREMFYA": 58.39221289374553}
\ No newline at end of file
+{"EYLEA": 686.9862716449983, "null": 1.0987122816961326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6165.json
index 4a27eb584d3..63084479146 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6165.json
@@ -1 +1 @@
-{"BARACLUDE": 131.9844283127463, "OLANZAPINE": 10.93077297010494, "PEGASYS": 8.31624681105071, "PEGINTRON": 9.640458377205611}
\ No newline at end of file
+{"null": 0.5020245583541936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6166.json
index 67d5f91fe72..536d51d6a63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6166.json
@@ -1 +1 @@
-{"ABACAVIR": 30.04171271939711, "ADEFOVIR": 51.170480911540366, "ALEMTUZUMAB": 14.311673228735405, "AMIKACIN": 47.53185946752846, "AMINOSALICYLIC": 3.1236267533958357, "ANIDULAFUNGIN": 41.06116395601374, "ATAZANAVIR": 17.206287741141267, "AZTREONAM": 55.97792805790844, "BASILIXIMAB": 16.922712759103167, "BIKTARVY": 2.5144235375035864, "BUSULFAN": 3.803979014492161, "CABOTEGRAVIR": 184.0805572413363, "CANCIDAS": 11.889853253028583, "CASPOFUNGIN": 42.36796436158664, "CELLCEPT": 1.358067091727706, "CELSENTRI": 34.94696541122213, "CICLOSPORIN": 2.2805934677175537, "CIDOFOVIR": 29.723942328537767, "COLISTIMETHATE": 60.92862420526939, "COMBIVIR": 2.996309201601516, "CUBICIN": 54.65440177605538, "CYTARABINE": 4.700790345025746, "DAPTOMYCIN": 81.02339386579516, "DARUNAVIR": 100.8737448008916, "DEXAMETHASONE": 1.7893098647050292, "DOLUTEGRAVIR": 83.16547948207413, "EFAVIRENZ": 32.00898742464371, "EMTRICITABINE": 43.67132036894899, "ENTECAVIR": 39.47302722295338, "EPIVIR": 7.643189522437596, "ERTAPENEM": 36.75798309471927, "GANCICLOVIR": 80.30511535194721, "HEPSERA": 7.553551912943149, "HUMIRA": 4.906327159919575, "ISENTRESS": 4.723258805631885, "LAMIVUDINE": 26.15368890218628, "LEVOFLOXACIN": 26.729323661118897, "MICAFUNGIN": 31.156905845030607, "NOXAFIL": 5.083665961297556, "OSELTAMIVIR": 108.42485152512316, "POSACONAZOLE": 56.69041788506062, "REKAMBYS": 96.76241974462664, "RIBAVIRIN": 3.805979651383172, "TAMIFLU": 17.821919168165415, "TIGECYCLINE": 136.85464308207028, "TIVICAY": 11.68661893294461, "TOBRAMYCIN": 45.98290959042277, "VFEND": 1.5065273877741483, "VORICONAZOLE": 20.880268940562104}
\ No newline at end of file
+{"null": 3.484806290653003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6167.json
index f667e9f2619..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6167.json
@@ -1 +1 @@
-{"AFINITOR": 2.224091513190162, "ATRIPLA": 6.539336186316638, "AVANDIA": 1.6330742006760628, "BONVIVA": 29.343236651921647, "DEXAMETHASONE": 4.900137601318927, "ENBREL": 2.2000042427460413, "EVENITY": 48.53169007781396, "FASLODEX": 4.184496737752419, "FENTANYL": 3.1348902050892264, "FORSTEO": 11.0471333534074, "HEPSERA": 49.06039601632977, "IBRANCE": 3.957199147952972, "KEYTRUDA": 2.0494406788511426, "METHOTREXATE": 1.9981482142971705, "STRIBILD": 5.419408444349534, "SUTENT": 2.895902767683288, "TRUVADA": 4.969325355061479, "VIREAD": 17.89257424991074, "XOFIGO": 42.76582127475856, "XTANDI": 2.305351023381109}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6168.json
index c42b571d0ee..da1fd0291cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6168.json
@@ -1 +1 @@
-{"null": 2.517955561887787}
\ No newline at end of file
+{"ANTIBIOTICS": 96.89138874033952, "CHAMPIX": 3.18032499056214, "COMIRNATY": 0.1624084659427092, "CYMBALTA": 1.78339490748491, "TOZINAMERAN": 1.0552802989833383, "VAXZEVRIA": 0.3038922718868097, "ZYPREXA": 3.658862029781966, "null": 2.585878356977194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6169.json
index 9d1db466288..e843be21784 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6169.json
@@ -1 +1 @@
-{"ABILIFY": 19.17713849898944, "RISPERIDONE": 82.56907334482011, "null": 2.155481718464486}
\ No newline at end of file
+{"ABILIFY": 0.6690956308809022, "ALIMTA": 1.752849207914402, "APROVEL": 5.4333392555809095, "ARIPIPRAZOLE": 1.402503467333939, "ASPARAGINASE": 8.68460498726035, "BRINTELLIX": 2.944094417583337, "CICLOSPORIN": 0.3002050012259633, "COAPROVEL": 15.082802055931031, "COMIRNATY": 0.0203490020212984, "CYMBALTA": 7.860593643921877, "CYTARABINE": 2.17238025138904, "DEXAMETHASONE": 1.445030547277209, "DOCETAXEL": 0.9708693664292478, "DOXORUBICIN": 2.170291675945544, "DULOXETINE": 9.477484372004122, "EMEND": 6.334088484527775, "ESOMEPRAZOLE": 4.686240256111195, "EXFORGE": 1.7455451850590982, "IRBESARTAN": 3.073558305953341, "JEVTANA": 3.752455165499272, "KEPPRA": 2.846070609226251, "KEYTRUDA": 2.023032413469135, "LEVETIRACETAM": 2.180918036870101, "MICARDISPLUS": 15.451594909593137, "MIDAZOLAM": 1.7574201686121, "OLANZAPINE": 4.982549262391343, "OPDIVO": 1.2591354584771133, "PANTOPRAZOLE": 3.621512023712018, "PEGINTRON": 0.4052236004794639, "RIVASTIGMINE": 127.0636169739774, "SPIKEVAX": 0.0245117854714857, "SUTENT": 0.3744617649195716, "TAMIFLU": 1.1202212580549378, "TOVIAZ": 2.4605908820595768, "VFEND": 5.696799664278896, "ZYPREXA": 4.491925364503508, "null": 4.039572524974126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/617.json
index 7e7141e0cb2..716c1ede744 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/617.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/617.json
@@ -1 +1 @@
-{"null": 2.7785219446407257}
\ No newline at end of file
+{"STELARA": 28.99477233426612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6170.json
index 2fae8c257e5..c8694e292d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6170.json
@@ -1 +1 @@
-{"BENLYSTA": 83.54886481302421}
\ No newline at end of file
+{"ABACAVIR": 0.0583692472015508, "ABASAGLAR": 1.6575068512328854, "ABILIFY": 2.336709011145053, "ADALIMUMAB": 0.5069534284639136, "ADCETRIS": 1.2547526346549394, "ADENURIC": 0.6234291189286575, "ADVATE": 0.9165450494912432, "AFINITOR": 0.7711112324239713, "AIMOVIG": 1.4634813135723643, "ALDARA": 0.8696880465142095, "ALIMTA": 0.5750150043458807, "AMINOSALICYLIC": 0.3663445048616269, "ANORO": 1.3764056251537768, "APIDRA": 1.5745276876425092, "APIXABAN": 0.2373206864537571, "ARANESP": 0.2682557899495565, "ARAVA": 0.0275772185669179, "ARIPIPRAZOLE": 0.5222733293023629, "AUBAGIO": 0.244576245721538, "AVAMYS": 0.555215716196327, "AVASTIN": 0.1818382417972536, "AZATHIOPRINE": 0.6423451403982544, "BELIMUMAB": 1.509405929309169, "BENLYSTA": 6.838151745977968, "BETAFERON": 0.5463100299638081, "BETMIGA": 2.651116169060718, "BEVACIZUMAB": 0.1309630561494346, "BIKTARVY": 0.1643395065957139, "BRAFTOVI": 0.5052379972134948, "BRINTELLIX": 0.3883700054156291, "BUDESONIDE": 0.4029325886778017, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6171.json
index a76a7eec579..189efdb2505 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6171.json
@@ -1 +1 @@
-{"null": 2.5907254632306738}
\ No newline at end of file
+{"SUBOXONE": 170.134754859374, "null": 0.7686757609157693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6172.json
index eb66bb5f11a..9cf2cbedaea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6172.json
@@ -1 +1 @@
-{"null": 3.225583063227329}
\ No newline at end of file
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6173.json
index a30cca9ee4e..dc61f7d04c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6173.json
@@ -1 +1 @@
-{"null": 2.145723911501263}
\ No newline at end of file
+{"SOVALDI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6174.json
index 7181dd91e6a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6174.json
@@ -1 +1 @@
-{"null": 1.1878667024099252}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6175.json
index 4d6260fb2d1..5e72f682670 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6175.json
@@ -1 +1 @@
-{"NUCALA": 27.090908040473565, "OMALIZUMAB": 10.768901053867998, "XOLAIR": 39.524262476685344, "null": 2.50781131721724}
\ No newline at end of file
+{"BUMETANIDE": 1443.7830846389747, "null": 0.7261808941817974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6176.json
index 744d799ea36..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6176.json
@@ -1 +1 @@
-{"null": 2.848173647013041}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6177.json
index 051b73605c3..0652ad23af8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6177.json
@@ -1 +1 @@
-{"OPTIMARK": 1367.7014714439697}
\ No newline at end of file
+{"VIAGRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6178.json
index 3ec564bb072..09f6ad58920 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6178.json
@@ -1 +1 @@
-{"null": 5.992219891988702}
\ No newline at end of file
+{"null": 1.3283080620789878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6179.json
index 1ae6ceca82b..5a07b3bb90e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6179.json
@@ -1 +1 @@
-{"null": 9.99190506862145}
\ No newline at end of file
+{"BUPIVACAINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/618.json
index de434527b44..cc46ea10ac6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/618.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/618.json
@@ -1 +1 @@
-{"COMIRNATY": 5.827157835572923, "SPIKEVAX": 2.416036232546306}
\ No newline at end of file
+{"null": 1.3206517134204443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6180.json
index 03c1a28fc0e..d405bac950d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6180.json
@@ -1 +1 @@
-{"JARDIANCE": 8.888345771976178}
\ No newline at end of file
+{"null": 0.4819417230289597}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6181.json
index 9cecd026769..c43fc0d564d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6181.json
@@ -1 +1 @@
-{"null": 1.244470496613888}
\ No newline at end of file
+{"null": 2.8844455740745247}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6182.json
index d1cd2c0de9d..03b5a51a728 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6182.json
@@ -1 +1 @@
-{"VAXZEVRIA": 1.1025815765346625}
\ No newline at end of file
+{"ELIQUIS": 14.798363248431494, "PLAVIX": 11.314036481293806, "null": 1.1822533874561725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6183.json
index b150c51eb30..48198e5d56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6183.json
@@ -1 +1 @@
-{"null": 1.4259831885118324}
\ No newline at end of file
+{"null": 0.9986656045005448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6184.json
index 4ff93d086e1..b8ca5ebf89e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6184.json
@@ -1 +1 @@
-{"CETROTIDE": 654.9371394831838, "GONALF": 622.36807009238, "ORGALUTRAN": 925.225940880982}
\ No newline at end of file
+{"SUTENT": 5.733520818341887, "null": 1.334769063428159}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6185.json
index 832c8f7d3d3..c8718172ed1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6185.json
@@ -1 +1 @@
-{"ATRIPLA": 2.069212464389205, "CICLOSPORIN": 2.4010761102963984, "CYMBALTA": 1.5974497688631004, "ELIQUIS": 2.14136273154322, "EVENITY": 26.831616776128005, "EVISTA": 48.499415079187166, "EXJADE": 1.635223799669648, "FORSTEO": 25.022099327775365, "HUMALOG": 2.977328031505329, "IBRANCE": 1.4435052319850508, "JARDIANCE": 1.2317167606009587, "LANTUS": 1.0945032796124816, "METHOTREXATE": 1.3863592254102035, "OPSUMIT": 1.6625106822363291, "REVATIO": 5.63731821835583, "SIMPONI": 1.1871450391058398, "SOLIRIS": 1.753228511016166, "STRIBILD": 2.0078561174450296, "SUBOXONE": 1.7269556073399073, "TRELEGY": 2.8037332454507453, "TRUVADA": 3.904356311281637, "XELJANZ": 8.05332095859515, "XTANDI": 1.1133931404518458, "null": 1.3207480353931336}
\ No newline at end of file
+{"null": 0.836747143117295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6186.json
index a453d0e5c39..cc57fd0746b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6186.json
@@ -1 +1 @@
-{"COMIRNATY": 1.947862684820601}
\ No newline at end of file
+{"null": 1.233393595316033}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6187.json
index c4804df40c0..604703bd3a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6187.json
@@ -1 +1 @@
-{"ELIQUIS": 8.44189979001699, "ENOXAPARIN": 83.5619382405621, "PLAVIX": 9.703096181327036, "null": 2.72800811588569}
\ No newline at end of file
+{"null": 0.8452258041202194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6188.json
index d5c739c51e1..b41ba368e60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6188.json
@@ -1 +1 @@
-{"COVID19": 3.6600657481491448, "TOZINAMERAN": 6.114042540995697}
\ No newline at end of file
+{"null": 0.3700478415865874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6189.json
index 2c7f6f329ae..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6189.json
@@ -1 +1 @@
-{"ABACAVIR": 12.334426810172763, "GARDASIL": 7.775901971141212, "JARDIANCE": 8.329751717612467, "null": 1.1814207727118495}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/619.json
index 4cef0724046..7cc425e585b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/619.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/619.json
@@ -1 +1 @@
-{"null": 4.554081806157254}
\ No newline at end of file
+{"null": 0.5519605119142673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6190.json
index 3651bc2e128..8022c4b35e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6190.json
@@ -1 +1 @@
-{"null": 1.9278588677871185}
\ No newline at end of file
+{"BEVACIZUMAB": 10.89123203587931, "BUPRENORPHINE": 6.045108822670555, "CHAMPIX": 1.0456359670577, "COMIRNATY": 0.0926431393730292, "CYMBALTA": 2.4082160856861456, "DEXAMETHASONE": 1.388108927324513, "GARDASIL": 1.3824418331560175, "HUMALOG": 2.6163657281569965, "KALETRA": 2.999461786798583, "KEPPRA": 1.2884892646942188, "LANTUS": 3.9821989219914378, "OLANZAPINE": 2.948204640142205, "PEGASYS": 1.539540498031556, "SPIKEVAX": 0.4383228406926996, "SUBOXONE": 2.915550746623422, "SUTENT": 0.3546393001885707, "TAMIFLU": 4.829033897068582, "TOZINAMERAN": 0.564305428136651, "VAXZEVRIA": 0.1577493411309595, "ZYPADHERA": 14.516592500646311, "ZYPREXA": 2.902030991375747, "null": 2.1266777892539785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6191.json
index 55a3f555499..fa01a6cafcd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6191.json
@@ -1 +1 @@
-{"AMGEVITA": 121.14916487980284, "ATAZANAVIR": 2.2885052499429435, "COMIRNATY": 2.5150598844836654, "COSENTYX": 2.842511887247708, "COVID19": 1.1802885391893223, "ELLAONE": 24.28188440744931, "ENZALUTAMIDE": 7.067882601254196, "ESMYA": 15.667663094590742, "FASLODEX": 1.5589520107990784, "FORSTEO": 2.919926359122316, "GARDASIL": 2.351586182780637, "JARDIANCE": 1.1942693319034714, "NEULASTA": 4.292131070291559, "SPIKEVAX": 1.0556617411730085, "STIVARGA": 1.0248813842411288, "SUBOXONE": 1.0511716681735122, "TOVIAZ": 4.3015003600387685, "TOZINAMERAN": 1.634285891488352, "XOFIGO": 4.167684597142023, "XTANDI": 1.4836342608290494, "ZARZIO": 25.0254999581374}
\ No newline at end of file
+{"COMIRNATY": 0.5825134563770966, "GARDASIL": 4.899971239737133, "ROTATEQ": 15.284630442685868, "SHINGRIX": 109.4248946274265, "SPIKEVAX": 1.86617179426448, "TOZINAMERAN": 0.6523370807411621, "TWINRIX": 22.85280426762973, "VAXZEVRIA": 2.6731014549576826, "null": 0.4124181609614994}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6192.json
index 948cf75a2fc..daf2ce70b24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6192.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1828184250045617, "ELIQUIS": 2.2388169361472903, "NOVOSEVEN": 96.6587143580445, "VAXZEVRIA": 1.0636642149714488}
\ No newline at end of file
+{"ABILIFY": 0.8602027800500963, "ACE": 54.16071193622556, "ADALIMUMAB": 0.1763786949925034, "AIMOVIG": 1.2708850921234904, "ATRIPLA": 0.230606207169067, "AUBAGIO": 4.975032355126063, "BETMIGA": 4.789270373588477, "BUDESONIDE": 0.7732032080866965, "COMIRNATY": 0.4200622168238024, "COSENTYX": 0.9634583990001824, "CYMBALTA": 1.6230466257050746, "DEXAMETHASONE": 0.9361975151074874, "ELIQUIS": 0.8334854377653784, "FAMPYRA": 4.919130850829294, "FORSTEO": 2.057538055118504, "FORXIGA": 3.2135975427940684, "GARDASIL": 1.27405653967696, "HUMALOG": 0.9839271827476632, "IBRANCE": 0.6790657560973079, "JANUVIA": 0.8878879397221272, "JARDIANCE": 2.8545510399022267, "KEPPRA": 1.022500914982422, "KEYTRUDA": 0.3964758154281942, "KYMRIAH": 2.358406836584282, "LANTUS": 0.5652989712562595, "LYRICA": 1.015130283648483, "MELATONIN": 8.419950096987858, "OLANZAPINE": 2.407300519052325, "OXYBUTYNIN": 12.2114186684251, "PEGASYS": 0.4133668226322807, "PEGINTRON": 0.6601992840500792, "SHINGRIX": 0.673421356704226, "SPIKEVAX": 0.5222433554069296, "SUBOXONE": 0.8800785934040217, "SUTENT": 0.4515813339861751, "TOVIAZ": 6.274686445724933, "TOZINAMERAN": 0.7038786085748583, "VAXZEVRIA": 0.4930665493002544, "XELJANZ": 0.5781765604564072, "XTANDI": 2.3260090743721022, "YESCARTA": 13.276346641173468, "ZOSTAVAX": 1.6714720543800858, "ZYPREXA": 4.261679012117064, "null": 1.5377915938332598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6193.json
index 6dfe49e3303..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6193.json
@@ -1 +1 @@
-{"BRAFTOVI": 1.5208275783228176, "CELECOXIB": 2.08149580985475, "CLOPIDOGREL": 1.5241094547274487, "DABRAFENIB": 4.396866657824431, "DUOTRAV": 440.691716296677, "EMPAGLIFLOZIN": 4.204358201331185, "EUCREAS": 101.41832654564612, "FASENRA": 1.103866118128987, "FORXIGA": 3.2174127437509936, "GALVUS": 91.6266499843558, "IPILIMUMAB": 7.308260249922632, "IRBESARTAN": 5.745747651360943, "JANUMET": 6.37902902093416, "JANUVIA": 39.925947295972136, "JARDIANCE": 1.422882272671669, "KEYTRUDA": 13.813117370311137, "LIBTAYO": 24.370993007234965, "LINAGLIPTIN": 60.263806054218286, "METFORMIN": 186.7322681135001, "NIVOLUMAB": 8.241259495879213, "NOVONORM": 6.719764484327032, "ONGLYZA": 30.333624450156545, "OPDIVO": 4.0324965854222174, "PEMBROLIZUMAB": 17.85239913267581, "SITAGLIPTIN": 36.49822139696445, "STELARA": 2.347851611356385, "TREMFYA": 4.184461479573158, "TRULICITY": 1.4079546859545906, "VELMETIA": 20.90526843295087, "VILDAGLIPTIN": 350.16633668975106, "XARELTO": 2.415875461209798, "null": 1.2794125540768069}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6194.json
index 630ab618f36..409e8e0126f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6194.json
@@ -1 +1 @@
-{"ABATACEPT": 10.652675469681675, "ADALIMUMAB": 24.43070073020857, "APREMILAST": 2.069948935221054, "APREPITANT": 1.1514804146500084, "ARAVA": 98.96507651564156, "CIMZIA": 3.6586710550476425, "EUCREAS": 2.385749495898354, "RITUXIMAB": 1.5460987774867168}
\ No newline at end of file
+{"AIMOVIG": 129.55221583962555, "NEULASTA": 91.83551177133874, "null": 0.8273854288420193}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6195.json
index 4ec99b8ba62..0e04866f667 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6195.json
@@ -1 +1 @@
-{"null": 2.4684870470463327}
\ No newline at end of file
+{"ARAVA": 1.3447801925655425, "CICLOSPORIN": 2.371879355593005, "CLOPIDOGREL": 2.904972819773449, "ELIQUIS": 1.1559328262532995, "ENTRESTO": 2.2431440202247144, "HUMALOG": 5.079485179653728, "KEPPRA": 1.7727711346163202, "LANTUS": 2.186681001019407, "PLAVIX": 1.3557596401545329, "XELJANZ": 1.1111189909271573, "null": 2.590149607898906}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6196.json
index f6787922fc6..31471917fd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6196.json
@@ -1 +1 @@
-{"JARDIANCE": 59.22820325825489}
\ No newline at end of file
+{"ABASAGLAR": 26.08744557641807, "ABILIFY": 1.1008191729357986, "ACTOS": 2.119561135876678, "ACTRAPID": 3.402394032769598, "ADALIMUMAB": 0.0281066199333754, "ADENURIC": 1.7768583521938155, "ADVATE": 1.86162470836304, "AERIUS": 1.4966639843854992, "AFINITOR": 0.4057824994561712, "AIMOVIG": 2.80964397549574, "AMINOSALICYLIC": 0.8568718025460151, "ANORO": 1.1748945857195254, "APIDRA": 5.78755320013322, "ARANESP": 0.5450948280241674, "ARAVA": 0.0273515382413362, "ARIPIPRAZOLE": 3.074634440769851, "AVAMYS": 1.055543678478107, "BEDAQUILINE": 1.3360068199788733, "BENLYSTA": 1.575863476746004, "BETAFERON": 1.2841172787396125, "BRIDION": 4.5759266561682015, "BRILIQUE": 0.5971687074226398, "BRIVIACT": 0.8805733547743047, "BUMETANIDE": 3.149264068794942, "BUPIVACAINE": 1.0648744969115025, "BUPRENORPHINE": 0.7052052727585276, "BYDUREON": 7.723864008342201, "BYETTA": 1.913571862414922, "CAELYX": 0.5552371535967927, "CANCIDAS": 2.364643035261509, "CARBIDOPA": 4.083300904835598, "CELLCEPT": 0.2468783868483777, "CHAMPIX": 0.6362799832513928, "CICLOSPORIN": 0.5933112495947155, "CIMZIA": 1.1737041016148944, "CLADRIBINE": 3.841706100586476, "CLOPIDOGREL": 0.956161250481021, "COLLAGENASE": 26.17725192161104, "COMIRNATY": 0.0957394434458229, "COSENTYX": 4.585015294674072, "CUBICIN": 0.9046318372360206, "CYMBALTA": 0.4734990474408965, "DARZALEX": 0.6259516306655097, "DESLORATADINE": 3.005280615616549, "DEXAMETHASONE": 0.4235335040747207, "DEXMEDETOMIDINE": 3.450575076430014, "DULAGLUTIDE": 8.015056903867183, "DULOXETINE": 0.9963635075385642, "EFIENT": 4.010552341133006, "ELIQUIS": 0.9754514521461014, "EMPAGLIFLOZIN": 1.3347990922727486, "ENOXAPARIN": 0.9273225210263086, "ENTACAPONE": 2.009071232631149, "ENTRESTO": 2.03495480429601, "ENTYVIO": 1.671641425809938, "ERLEADA": 0.7548497061555569, "EVENITY": 4.0870254340427525, "EVISTA": 0.5401937129445789, "EXFORGE": 1.8550895650368704, "EXJADE": 0.3919331818820947, "EYLEA": 1.4316775792391194, "FASENRA": 0.2921526494994642, 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0.8392118215477443, "PEGASYS": 0.4300922102500277, "PEGINTERFERON": 0.6463731700016696, "PEGINTRON": 0.9122644103360577, "PEMBROLIZUMAB": 1.2225850859654654, "PLAVIX": 0.5970533140133246, "PLEGRIDY": 0.45082049902099, "PUREGON": 21.50022029979359, "RAPAMUNE": 0.6665140854536409, "RASBURICASE": 8.514772546174397, "RASILEZ": 0.6607905820614068, "RELVAR": 1.3172922371031983, "REVATIO": 1.3797923743706724, "RIBAVIRIN": 0.4672317176623277, "RINVOQ": 0.4393715629244692, "ROTATEQ": 0.5267010134101641, "SAMSCA": 3.77453488412448, "SAXENDA": 1.0970944677069436, "SHINGRIX": 0.2575795597098661, "SIFROL": 1.3053675367072646, "SILDENAFIL": 0.736731942826286, "SIMPONI": 3.3959134483794533, "SOLIRIS": 8.971283679950222, "SOMATROPIN": 1.4762573556592733, "SPIKEVAX": 0.0441204224343858, "STALEVO": 2.822161459869556, "STELARA": 1.8471426519078171, "STIVARGA": 0.5019425680039556, "SUTENT": 0.1646837904831492, "TAMIFLU": 0.6139033339388242, "TASIGNA": 0.8673211432405356, "TEMODAL": 0.9609317748437411, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6197.json
index fd228ade14a..673cd11a2c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6197.json
@@ -1 +1 @@
-{"XIAPEX": 5477.844931612342, "null": 4.55779258879207}
\ No newline at end of file
+{"ACTRAPID": 27.30343797426918, "AIMOVIG": 11.13121125142736, "APIDRA": 18.20444176572348, "ARANESP": 1.3365803749788123, "BETAFERON": 15.98675005858739, "BYDUREON": 35.1547764006719, "BYETTA": 3.9729771557288247, "COSENTYX": 5.799490041082088, "FASENRA": 14.828976566696236, "FIASP": 86.37597565844638, "HUMALOG": 1.0315892847833443, "INSULATARD": 23.117799935883717, "INSULIN": 3.614264156967711, "KESIMPTA": 8.448579496906097, "LANTUS": 15.015294149363324, "LEVEMIR": 46.90037102727569, "NEULASTA": 5.448923004220324, "NOVORAPID": 80.00377033005442, "OMNITROPE": 80.89170409175007, "OPSUMIT": 1.096237569417445, "PLEGRIDY": 11.83454769491556, "SAXENDA": 8.670079993897534, "SIMPONI": 1.5828517872516394, "TOUJEO": 28.157920482205046, "TRESIBA": 60.85943914980587, "VICTOZA": 3.225389907080324, "null": 1.3950737923952805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6198.json
index 4b728ed483f..2d4d06615b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6198.json
@@ -1 +1 @@
-{"VIAGRA": 92.49527136490808, "null": 2.0617677569376225}
\ No newline at end of file
+{"NOVORAPID": 31.84270283817101, "null": 2.921295290734162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6199.json
index 4aaca40067a..e128131ba9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6199.json
@@ -1 +1 @@
-{"JARDIANCE": 80.93120106568271}
\ No newline at end of file
+{"CINRYZE": 62.40536052352757, "DARZALEX": 12.651436699663108, "FENTANYL": 2.595368682525147, "HIZENTRA": 7.360437930170771, "HUMAN": 18.3238147281793, "IBUPROFEN": 18.85882844249825, "LEMTRADA": 24.455131226712517, "MIDAZOLAM": 11.221199477128854, "PRIVIGEN": 37.94492432989593, "null": 3.409633164414902}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/62.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/62.json
index 5e4500978b0..a6ac9fa73f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/62.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/62.json
@@ -1 +1 @@
-{"CYMBALTA": 6.353675390827741, "DULOXETINE": 16.241065931820852, "EPIVIR": 28.384495193864304, "LATUDA": 14.08647118210864, "OLANZAPINE": 5.886206226120309, "ZYPREXA": 6.440529739071105, "null": 2.649708048519545}
\ No newline at end of file
+{"CHAMPIX": 8.849465175938487, "COMIRNATY": 0.1851596028828348, "XYREM": 109.88972220291755, "null": 2.234926950691295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/620.json
index 234790f4fde..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/620.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/620.json
@@ -1 +1 @@
-{"null": 2.562402753033977}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6200.json
index 98c5782b6bf..8d26de5c6b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6200.json
@@ -1 +1 @@
-{"JARDIANCE": 39.36406010924392, "VIAGRA": 59.62887672071078, "null": 1.008089787236376}
\ No newline at end of file
+{"ABASAGLAR": 7.1564066121743215, "AIMOVIG": 0.8614016468954115, "AMINOSALICYLIC": 20.628353497619106, "BEDAQUILINE": 106.92682378638328, "BENLYSTA": 1.2388680034345445, "CIRCADIN": 7.978143020267403, "COSENTYX": 0.3094264181287707, "CYMBALTA": 0.5142570168719351, "DELAMANID": 93.08773083028922, "DELTYBA": 48.88141291747056, "DENOSUMAB": 5.003583658567151, "DULOXETINE": 1.1657077584595026, "ELIQUIS": 0.3119321097203035, "EPCLUSA": 4.173362157845683, "ESOMEPRAZOLE": 2.399626364403326, "FORSTEO": 15.616738779076888, "HARVONI": 3.625035421755349, "HUMALOG": 9.035814555325114, "HYDROCORTISONE": 1.446228601148907, "IBUPROFEN": 2.1952434858681915, "INFLIXIMAB": 4.645671658960571, "INSULIN": 2.206445927033962, "KEPPRA": 0.3497618836271213, "KEYTRUDA": 0.2599429829895125, "LANTUS": 0.2132911730945527, "LEMTRADA": 4.581712432490049, "LONSURF": 1.8300046587667165, "MELPHALAN": 7.582793937870976, "NEVANAC": 26.282126748301376, "NEXAVAR": 0.5997744249142213, "NUCALA": 1.8531580552188247, "PEGINTERFERON": 1.1175205296999655, "PLAVIX": 1.2568504499438249, "QUTENZA": 12.614906158993572, "RAPISCAN": 28.680268685146057, "RIBAVIRIN": 1.411829971152063, "SOLIRIS": 0.5729134966902535, "SOVALDI": 6.3377282494176175, "STELARA": 0.503157408633453, "null": 3.726612133443832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6201.json
index eb7b46a3e41..87d7ddfda24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6201.json
@@ -1 +1 @@
-{"JARDIANCE": 129.76614203802706}
\ No newline at end of file
+{"HUMALOG": 7.7613840442941395, "NOXAFIL": 121.41060628921166, "null": 3.1754837560714613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6202.json
index 7328a2e7554..d1078ec3a99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6202.json
@@ -1 +1 @@
-{"null": 1.690422363166397}
\ No newline at end of file
+{"HUMALOG": 25.888434204392727, "null": 2.125837686607829}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6203.json
index 2cd720fd626..b069bafaff9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6203.json
@@ -1 +1 @@
-{"FORXIGA": 47.41690754376895, "JARDIANCE": 99.12479650292588, "VIAGRA": 37.17598490690295}
\ No newline at end of file
+{"ABATACEPT": 0.878344664559182, "ABILIFY": 0.3844422887156405, "ADALIMUMAB": 1.5591875772637556, "AFINITOR": 0.3034437223243491, "AIMOVIG": 6.444238197451657, "APIDRA": 1.4139655208151078, "APREMILAST": 4.563710557295238, "ARANESP": 15.689481997524505, "ARAVA": 1.4105272727552345, "ARIPIPRAZOLE": 0.4147044157532225, "ATAZANAVIR": 1.677844297072591, "AUBAGIO": 0.3321712536942428, "BEVACIZUMAB": 0.90745497586911, "BIKTARVY": 0.7386441746199366, "BONVIVA": 1.8699715385855769, "BORTEZOMIB": 1.346479391873805, "BUDESONIDE": 0.2726340826986554, "BUPIVACAINE": 8.871800324173195, "BUPRENORPHINE": 1.7935821309893265, "CELLCEPT": 2.461588103665055, "CHLORHEXIDINE": 0.8926654975135928, "CIMZIA": 0.3128514612626756, "CLOPIDOGREL": 1.125985257194441, "COMIRNATY": 0.1551979041759435, "COSENTYX": 3.513675582693747, "CYMBALTA": 0.2074859444526054, "CYTARABINE": 0.8390659869924696, "DACLIZUMAB": 47.69434844439749, "DARBEPOETIN": 54.897210869561945, "DEXAMETHASONE": 0.5497542232816173, "DOXORUBICIN": 1.479284256269692, "ENBREL": 0.8007077294435616, "ENOXAPARIN": 1.6364417527559012, "EVENITY": 1.8890922397004468, "FASLODEX": 1.7136156155058158, "FENTANYL": 11.53939739315429, "FLUTICASONE": 10.585468672126982, "FORSTEO": 0.5805480783931628, "GANCICLOVIR": 1.986395058704528, "GARDASIL": 2.1604787777969023, "HIZENTRA": 0.7514012095104907, "HUMALOG": 1.9116053240205544, "HYDROCORTISONE": 1.733335767509128, "INSULIN": 0.9239319323806564, "ISENTRESS": 3.943264942882293, "JANUMET": 0.3484477280099642, "JANUVIA": 0.3132346977129826, "JARDIANCE": 0.7775486990255048, "KEPPRA": 1.330097641576556, "KEYTRUDA": 0.2251324328293777, "LACOSAMIDE": 3.531745660410877, "LANTUS": 1.0157982687689997, "LEVEMIR": 0.9090911230489634, "LEVETIRACETAM": 2.565387640515437, "MELATONIN": 3.9078151352585913, "MELPHALAN": 7.8080470551423025, "MENVEO": 1.8361495135762087, "METHOTREXATE": 0.3089120873021074, "MIDAZOLAM": 4.740597248222714, "MIRABEGRON": 8.5014818066818, "NEULASTA": 1.1073710955921496, "NEXAVAR": 0.2508310551355616, "NIMENRIX": 1.9344531698909573, "NOT": 1.340972433947841, "NOVORAPID": 0.6573853000517168, "NOXAFIL": 3.450011556572698, "OLANZAPINE": 0.4697504446354194, "ORGALUTRAN": 21.48588750191, "PEGASYS": 0.2335622690333799, "PLAVIX": 0.2940784623801608, "ROTATEQ": 1.2715422325118722, "RUCONEST": 6.665687103122151, "SAXENDA": 0.7304714574193863, "SHINGRIX": 4.31708336266103, "SIMPONI": 0.3803613957729984, "SOMAVERT": 16.851669547281585, "SPIKEVAX": 0.1822474774060249, "STELARA": 2.053890608137908, "SUBOXONE": 2.0721780577005378, "SUFENTANIL": 2.829203323601296, "SYCREST": 23.306713323462887, "TOBRAMYCIN": 3.3041985821778623, "TOZINAMERAN": 0.5372563166461046, "TREMFYA": 2.452203394120468, "TRULICITY": 1.5611877603453896, "VAXZEVRIA": 0.3603635282314383, "VIAGRA": 0.6258381046834363, "XOLAIR": 3.1794267996872017, "ZOSTAVAX": 4.049185941451907, "ZYPADHERA": 2.897577996630229, "ZYPREXA": 0.4011503802604407, "null": 1.9774977217001743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6204.json
index b9441a0011d..0ea4de41b87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6204.json
@@ -1 +1 @@
-{"SUTENT": 12.010963633660152, "null": 1.730128329454912}
\ No newline at end of file
+{"BUDESONIDE": 106.06717249639952, "MELATONIN": 888.6573787653879}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6205.json
index 7a471bf1dd3..860fa51d570 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6205.json
@@ -1 +1 @@
-{"XIAPEX": 2783.614869252263, "null": 5.8435418733158135}
\ No newline at end of file
+{"ABASAGLAR": 4.18889015468786, "ABILIFY": 33.0992703629578, "AERIUS": 5.549103945383997, "AIMOVIG": 0.8680466561608766, "ALEMTUZUMAB": 2.0517981229919884, "ARIPIPRAZOLE": 53.61541065799989, "BIKTARVY": 4.289390165041169, "BRINTELLIX": 8.301213626368801, "BYDUREON": 2.8732170243969075, "BYETTA": 1.4255285658059749, "CHAMPIX": 5.760277069053683, "COMIRNATY": 0.1393255363738526, "COSENTYX": 0.5064865276773451, "CYMBALTA": 1.539927507810547, "DESLORATADINE": 8.575065830098017, "DEXAMETHASONE": 0.8492773245502963, "DULOXETINE": 1.9081242488455616, "ELIQUIS": 0.1723543576773308, "ELLAONE": 5.277451658542609, "ESOMEPRAZOLE": 2.5009263969898465, "FENTANYL": 0.636251828907467, "FORSTEO": 0.988911376391318, "FORXIGA": 1.5691571112915323, "FYCOMPA": 4.068681134055331, "GARDASIL": 0.4592544327612901, "HUMALOG": 0.99024912630548, "IBRANCE": 1.036519597342063, "INSULIN": 3.616464935646354, "JAKAVI": 2.3635478735914908, "JANUMET": 0.9474669505488466, "JANUVIA": 0.7687986514394902, "JARDIANCE": 2.0004967034200782, "KEPPRA": 0.4888235287081146, "KEYTRUDA": 0.2392439313120213, "LANTUS": 0.7986015371028797, "LATUDA": 7.884965215555664, "LEMTRADA": 2.0809520463656384, "LYRICA": 2.714810856208345, "OLANZAPINE": 9.938776201963472, "PEGASYS": 0.7877077289583525, "PEGINTRON": 0.4031496294633407, "RYBELSUS": 7.139285735278908, "SAXENDA": 14.291121642029738, "SOMATROPIN": 10.64671010133172, "SPIKEVAX": 0.0873000736656842, "SPINRAZA": 2.183575142400596, "SUTENT": 0.8479970014377364, "SYCREST": 13.876496757354449, "TOZINAMERAN": 0.1345100576756985, "TRULICITY": 2.629854708006699, "VAXZEVRIA": 0.2046018133266184, "VICTOZA": 2.8509619965252115, "XELJANZ": 1.3639767181687097, "ZYPREXA": 18.71879465352872, "null": 1.1834114838354433}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6206.json
index 80dad6db7ef..39cf03ea641 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6206.json
@@ -1 +1 @@
-{"ELIQUIS": 8.350988172112316, "JARDIANCE": 6.312966461825265, "SUTENT": 3.411882391631947, "VIAGRA": 173.79974977648993, "null": 1.0226606592690042}
\ No newline at end of file
+{"AVAMYS": 4.517816123568488, "CELLCEPT": 2.6211903276944715, "COMIRNATY": 0.3020899548325913, "FENTANYL": 7.789305022210832, "INCRUSE": 31.689351932243348, "KAFTRIO": 10.382756374027831, "LEVETIRACETAM": 3.764786053933884, "MEPOLIZUMAB": 21.00565974034652, "MIDAZOLAM": 9.801499814588771, "NUCALA": 3.163762660904344, "OLANZAPINE": 3.335655437988066, "OMALIZUMAB": 8.759877987701966, "OPSUMIT": 2.9273001865122685, "ORKAMBI": 40.84965511716271, "SPIKEVAX": 0.2100936631194689, "SPINRAZA": 32.878367472672025, "SYNAGIS": 17.760013140355337, "TRELEGY": 9.785651922750697, "UMECLIDINIUM": 73.5464981200453, "VAXZEVRIA": 0.0844472332344552, "XOLAIR": 1.8646455167103824, "null": 1.6134385602754433}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6207.json
index 2e658ad1745..8b50b3e4b71 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6207.json
@@ -1 +1 @@
-{"JARDIANCE": 151.01235003664917}
\ No newline at end of file
+{"COMIRNATY": 0.4575065253181187, "FIASP": 353.33082829694865, "HUMALOG": 14.366699444969775, "NOVORAPID": 122.5946050837822, "SPIKEVAX": 0.6942066457006074, "VAXZEVRIA": 0.328754714367185, "null": 0.2301919214229945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6208.json
index 01572d9cebb..8133e390ca7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6208.json
@@ -1 +1 @@
-{"null": 3.206012394354377}
\ No newline at end of file
+{"COMIRNATY": 1.875913085165953, "null": 0.6671588520219112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6209.json
index 2c7f6d38443..2e743f451aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6209.json
@@ -1 +1 @@
-{"JARDIANCE": 8.287050317828355, "null": 2.143384173871464}
\ No newline at end of file
+{"ALEMTUZUMAB": 3.1736517117456544, "BRILIQUE": 4.813641116255154, "BRINTELLIX": 2.5082444988082977, "CIMZIA": 1.2436977588361424, "CLOPIDOGREL": 3.3437362930216934, "COMIRNATY": 0.8041400266686951, "CYMBALTA": 0.4685796646465215, "DEXAMETHASONE": 1.845974760705435, "ELIQUIS": 3.8230318024983214, "ENBREL": 2.698544130869559, "GARDASIL": 3.3752282841523056, "HUMIRA": 1.8537613831960549, "IBRANCE": 1.1792554815737817, "JANUVIA": 2.21863202571045, "NPLATE": 7.163117585870479, "PEGASYS": 1.8949000997205216, "PEGINTRON": 0.9798392586695684, "PLAVIX": 6.00188512340556, "SPIKEVAX": 0.5662690081207667, "SUTENT": 1.7516397303964883, "TOZINAMERAN": 0.6139380068550648, "VAXZEVRIA": 1.3192385885163544, "VOTRIENT": 1.7339383466652607, "XARELTO": 9.307048360865997, "XELJANZ": 2.4480115133677045, "ZOSTAVAX": 2.8476419040684235, "null": 0.8497773359501231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/621.json
index b2f5a8a11db..19a7bd44c12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/621.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/621.json
@@ -1 +1 @@
-{"AMELUZ": 406.4519230286784, "QUTENZA": 252.8061759506137, "VAXZEVRIA": 4.4541578092943865, "null": 2.1124970914036787}
\ No newline at end of file
+{"null": 4.111158942395831}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6210.json
index a76a7eec579..84c9f81db07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6210.json
@@ -1 +1 @@
-{"null": 2.5907254632306738}
\ No newline at end of file
+{"ARAVA": 0.5084670491338498, "COMIRNATY": 0.947104824732392, "CYMBALTA": 2.097195863062332, "IBRANCE": 1.8131785486899, "NUCALA": 5.661340844195672, "OMALIZUMAB": 4.436976884740267, "SPIKEVAX": 0.6796816456576259, "TOZINAMERAN": 0.8708997949259852, "VAXZEVRIA": 0.2521284705874935, "XOLAIR": 2.716521190795712, "null": 1.4252321654422255}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6211.json
index a3d071df821..16aab93bd3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6211.json
@@ -1 +1 @@
-{"FORXIGA": 9.46494293104424, "JARDIANCE": 11.245915468023275, "SILDENAFIL": 16.692366677633938, "SUTENT": 1.2131965288331148, "VIAGRA": 423.2955968071438, "XIAPEX": 436.1699933696145, "null": 1.0451152883266457}
\ No newline at end of file
+{"null": 1.882952501881872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6212.json
index f1f31d1b11e..19d49864fa4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6212.json
@@ -1 +1 @@
-{"null": 10.013420854280112}
\ No newline at end of file
+{"COMIRNATY": 1.3756135316668463, "MODERNA": 12.575984174921205, "NUCALA": 6.835419761778538, "SPIKEVAX": 0.5845128652642666, "TOZINAMERAN": 1.7040571216696443, "VAXZEVRIA": 0.876021686376519, "null": 0.8543710772773501}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6213.json
index ca943c362e8..590c46e8962 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6213.json
@@ -1 +1 @@
-{"JARDIANCE": 27.867841269942637, "VIAGRA": 74.23997461824624, "XIAPEX": 1571.5565979304415, "null": 1.922463216527268}
\ No newline at end of file
+{"DARZALEX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6214.json
index e1a26df9c57..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6214.json
@@ -1 +1 @@
-{"JARDIANCE": 14.18390522947653, "null": 1.8275020751286093}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6215.json
index a6fdf545538..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6215.json
@@ -1 +1 @@
-{"VIAGRA": 260.1887563605293, "null": 1.7118823319212062}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6216.json
index f9271c5ae19..ef5ec371c8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6216.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1932341408611689}
\ No newline at end of file
+{"GONALF": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6217.json
index 3a48a0fcc77..b5fffaf4307 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6217.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6217.json
@@ -1 +1 @@
-{"FORXIGA": 15.460999022848425, "JARDIANCE": 21.24784154423476, "VIAGRA": 207.54539720643365, "null": 2.064668594260769}
\ No newline at end of file
+{"ENTYVIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6218.json
index 4a8c5298a0f..6c91aa1873e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6218.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6218.json
@@ -1 +1 @@
-{"JARDIANCE": 23.740224185475597, "VIAGRA": 61.48212710937026, "null": 2.721448279980755}
\ No newline at end of file
+{"BRINTELLIX": 11.855333718343385, "CHAMPIX": 8.391871354704096, "COMIRNATY": 0.2605695553076548, "VAXZEVRIA": 0.239263840282408, "null": 2.837220086893687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6219.json
index d4244041db7..fa63acb3950 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6219.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6219.json
@@ -1 +1 @@
-{"AVONEX": 55.63652702114012, "CLOPIDOGREL": 5.363863610229037, "COSENTYX": 4.725003900887934, "EFAVIRENZ": 14.573759240115283, "ELIQUIS": 2.7015006697822392, "EXFORGE": 5.396325214414675, "EXJADE": 3.2601980597325584, "IBUPROFEN": 4.539264714386686, "PEGINTRON": 1.8610477063636848, "PLAVIX": 4.693988125896942, "ZOSTAVAX": 2.7326662008311007, "null": 2.5372584319444886}
\ No newline at end of file
+{"null": 1.3183814393892817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/622.json
index 63653d88c46..b135a0ed020 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/622.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/622.json
@@ -1 +1 @@
-{"ALDARA": 20.30873062154639, "AMELUZ": 126.01282470419216, "BETAFERON": 1.5367632057426417, "COMIRNATY": 1.8703840032981005, "COVID19": 10.221302054320926, "EVRA": 5.053048374388454, "INHIXA": 5.42111609672694, "KENTERA": 9.698582669459917, "MIRVASO": 11.539053877987769, "NEULASTA": 2.804927795048449, "QUTENZA": 155.62902365216024, "SPIKEVAX": 1.5089148071450642, "SYNAGIS": 1.0205756608863292, "VAXZEVRIA": 1.4446519875487862, "ZYCLARA": 12.679312445768767}
\ No newline at end of file
+{"COMIRNATY": 0.7472126829640091, "null": 1.2699952439977171}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6220.json
index 6da3b50a994..18f9417e9b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6220.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6220.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 24.48181441598375, "ELIQUIS": 4.346921126301893, "ENBREL": 36.7568383497984, "PLAVIX": 27.74344239253145, "XARELTO": 20.91946217650754}
\ No newline at end of file
+{"MISOPROSTOL": 44.36925233704665, "null": 298.03526295781927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6221.json
index 648f94f35e5..4c076974747 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6221.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6221.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 32.01743501687865, "null": 2.065602363262541}
\ No newline at end of file
+{"null": 3.440318901667623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6222.json
index 696cafb584e..32281de29a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6222.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6222.json
@@ -1 +1 @@
-{"AVANDIA": 30.486712478463133, "CLOPIDOGREL": 14.56132232579404, "ELIQUIS": 15.628145133870683}
\ No newline at end of file
+{"KEPPRA": 10.983927120617308, "null": 1.309008493234746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6223.json
index 03b6b0830bc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6223.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6223.json
@@ -1 +1 @@
-{"null": 1.499467059653714}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6224.json
index c344f2602e6..778f4aad1f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6224.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6224.json
@@ -1 +1 @@
-{"KEYTRUDA": 8.080314761591087}
\ No newline at end of file
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6225.json
index 5c54809b054..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6225.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6225.json
@@ -1 +1 @@
-{"null": 2.59950973928883}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6226.json
index 340967f62ca..05f9a8c651f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6226.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6226.json
@@ -1 +1 @@
-{"AFINITOR": 1.3907204929051753, "ALIMTA": 3.5968138033072456, "BEVACIZUMAB": 2.892702846091133, "BUPIVACAINE": 45.97860329989782, "CABOMETYX": 3.6771202130970737, "COMIRNATY": 3.242313946243213, "DEXAMETHASONE": 1.0522072373276483, "FENTANYL": 1.791203085220589, "FIRDAPSE": 7.632333974926924, "JEVTANA": 8.830975425837613, "KETOCONAZOLE": 30.796717521955948, "LEVETIRACETAM": 1.368260884793688, "LONSURF": 11.054507460595712, "NEXAVAR": 2.4707477031365843, "OLANZAPINE": 1.0227374372827551, "OPDIVO": 3.0128219635834146, "PEMBROLIZUMAB": 2.689200158241418, "SPIKEVAX": 1.240659096417738, "STIVARGA": 3.938495428818477, "SUTENT": 1.1674261408304365, "TOVIAZ": 6.270564642182218, "TWINRIX": 6.010888894213508, "VOTRIENT": 1.741413156015736, "XTANDI": 2.2526829574376426}
\ No newline at end of file
+{"APIDRA": 2.9070721110680324, "CICLOSPORIN": 0.8239446000519675, "COMIRNATY": 1.1961063551579854, "FASLODEX": 5.236855850015062, "FENTANYL": 1.5853755739416375, "GARDASIL": 3.849267172718184, "INSULIN": 2.056809051639327, "LANTUS": 0.8362440565200706, "MENVEO": 23.65567321618604, "NIMENRIX": 4.377577023650129, "OPTIMARK": 8.037262269118271, "SHINGRIX": 6.622242883776575, "SPIKEVAX": 1.420536698834983, "TOZINAMERAN": 7.240246727086626, "VAXZEVRIA": 1.0870733743540884, "null": 0.578880846858781}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6227.json
index 8e0f6c57f90..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6227.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6227.json
@@ -1 +1 @@
-{"HYDROCORTISONE": 114.31224896336468, "MEPOLIZUMAB": 41.02014716286871, "OMALIZUMAB": 182.6881870036343}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6228.json
index d955f6ba190..252393455cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6228.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6228.json
@@ -1 +1 @@
-{"COMIRNATY": 2.468570430037872, "COVID19": 4.958457251061391, "CYMBALTA": 1.7623293357009775, "SPIKEVAX": 1.8869123471757228, "TOZINAMERAN": 4.139391435415851, "VAXZEVRIA": 1.0869694335665678}
\ No newline at end of file
+{"COMIRNATY": 0.4687752705298114, "NIMENRIX": 195.46272851523128, "TOZINAMERAN": 3.141378474892707, "null": 0.478025912326444}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6229.json
index 4a07d6bf059..fa894bcc2ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6229.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6229.json
@@ -1 +1 @@
-{"EMTRICITABINE": 1588.5393538138464}
\ No newline at end of file
+{"FENTANYL": 6.196889910937904, "INFANRIX": 66.37719253618003, "KEPPRA": 3.972689761257669, "MIDAZOLAM": 31.114539273892635, "ZYPREXA": 3.038217069702191, "null": 3.446216791309263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/623.json
index a6be863cda0..f1ec610f206 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/623.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/623.json
@@ -1 +1 @@
-{"null": 11.386139095903053}
\ No newline at end of file
+{"null": 3.789616428224515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6230.json
index 3e80fafdd74..ba893a4f40d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6230.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6230.json
@@ -1 +1 @@
-{"ELIQUIS": 12.970036131262283}
\ No newline at end of file
+{"MMRVAXPRO": 73.2441974743109, "null": 0.6354253074591604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6231.json
index 5b931cbb759..5c0896c8625 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6231.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6231.json
@@ -1 +1 @@
-{"ADCIRCA": 6.914063135777443, "ADEMPAS": 3.158395033791112, "AFINITOR": 2.94644895546623, "ALEMTUZUMAB": 2.9760253923020445, "ALIMTA": 2.409438826500479, "AMBRISENTAN": 4.064654600447698, "AVANDAMET": 3.9064900829692415, "AVANDIA": 5.3884355503676105, "BENLYSTA": 1.8590919452515469, "BEVACIZUMAB": 1.2367534424721054, "BOSULIF": 17.401747880928824, "BRILIQUE": 1.1372128731624076, "BUSULFAN": 5.195245376335139, "CABOMETYX": 1.0594222414735963, "CELLCEPT": 1.3992448182763375, "CICLOSPORIN": 1.0864062222077522, "COMBIVIR": 1.5533354275799425, "COMIRNATY": 1.2489537418081849, "CYTARABINE": 1.791505837284506, "DEXAMETHASONE": 1.054199166813972, "DOLUTEGRAVIR": 6.064657975868012, "ELIQUIS": 1.5324501665545722, "EMTRICITABINE": 4.316504174223839, "ESBRIET": 1.1798587454114289, "ESOMEPRAZOLE": 2.5573390850603825, "FASLODEX": 1.2109627872014508, "FILGRASTIM": 2.1902240367957204, "FULVESTRANT": 1.8610754945124504, "GEFITINIB": 3.7159938383499753, "GLIVEC": 2.972249723445658, "HERCEPTIN": 3.5529399031931543, "HUMALOG": 3.070549191432192, "ICLUSIG": 7.548719133276303, "IMATINIB": 3.617691784872147, "INLYTA": 1.249407633224905, "INSULIN": 1.2042238213893013, "IPILIMUMAB": 1.1243101221626934, "IRESSA": 3.785930921858004, "JAKAVI": 1.6194296165597009, "KEYTRUDA": 3.4181474689127325, "KYPROLIS": 2.608800387345995, "MACITENTAN": 9.248181935817447, "MIDAZOLAM": 1.3334071566233772, "MULTAQ": 2.284978435869312, "MYCOPHENOLATE": 1.4554613491354365, "NILOTINIB": 9.851013085097676, "NOXAFIL": 2.384937464532678, "NPLATE": 1.0149385360882628, "OPDIVO": 1.3746153210683116, "OPSUMIT": 5.225951097576325, "PACLITAXEL": 2.0323053314220214, "PEMBROLIZUMAB": 2.186758890047929, "PEMETREXED": 1.5894934622176138, "RAPAMUNE": 5.737647637189616, "REVATIO": 4.303318454889912, "RUBRACA": 1.2410355721072066, "SILDENAFIL": 3.635812119953557, "SOLIRIS": 2.042029565695339, "SPRYCEL": 37.59568427821048, "SUTENT": 2.127330191892572, "TAGRISSO": 3.709610246804262, "TASIGNA": 8.404129158562077, "TORISEL": 3.248567297118669, "TRACLEER": 4.794408175707647, "TRACTOCILE": 11.84002971292918, "TRISENOX": 9.680716121109253, "VELTASSA": 2.061419099827796, "VOTRIENT": 1.923938371063147, "XALKORI": 6.813298819426448, "XARELTO": 1.2828513416310003, "YERVOY": 1.5049257153543871, "ZELBORAF": 3.235146468661178}
\ No newline at end of file
+{"ROTATEQ": 140.07736793415765, "SUBOXONE": 175.204627579188}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6232.json
index c5e6df4afba..cd864d96a49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6232.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6232.json
@@ -1 +1 @@
-{"ISENTRESS": 302.50208192980966}
\ No newline at end of file
+{"AZATHIOPRINE": 86.65654541247035, "SUBOXONE": 68.77082860541636, "null": 1.9361674713283776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6233.json
index cd522174601..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6233.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6233.json
@@ -1 +1 @@
-{"COMIRNATY": 2.691300251014165}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6234.json
index 42d0228a633..9e36c29470d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6234.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6234.json
@@ -1 +1 @@
-{"APIXABAN": 10.342562057030207, "BRILIQUE": 32.62433302234234, "CLOPIDOGREL": 17.07358004808956, "ELIQUIS": 25.05009917101124, "PLAVIX": 14.51154824823795, "TICAGRELOR": 16.089366722855882, "XARELTO": 24.289482190610336}
\ No newline at end of file
+{"null": 1.037185294654559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6235.json
index 0429c22878b..4e38b7557b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6235.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6235.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2768699644015051, "SPIKEVAX": 1.6762933416119945}
\ No newline at end of file
+{"EVEROLIMUS": 117.93038841103424, "KEPPRA": 7.413659287333687, "LEVETIRACETAM": 45.33390919673814, "ROTATEQ": 20.20028806648838, "SYNAGIS": 30.43452000910176, "VIGABATRIN": 355.6710013672589, "null": 2.8949874606110657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6236.json
index c457407d69c..afc427a24af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6236.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6236.json
@@ -1 +1 @@
-{"ABATACEPT": 3.0618943151788667, "ACLASTA": 3.342855518431429, "ADALIMUMAB": 5.686499454917296, "APIXABAN": 1.0167904570182045, "APREMILAST": 5.153502246351762, "ARAVA": 9.89118039729899, "BENLYSTA": 1.5276305123054568, "BUSILVEX": 3.152704432560703, "CIMZIA": 1.0015057005075094, "COMIRNATY": 4.70852925776631, "ERELZI": 3.8064003559620194, "NILOTINIB": 2.1593319854123867, "PEMBROLIZUMAB": 1.0316711672210697, "SPIKEVAX": 1.8320852871434812, "SPRYCEL": 1.191246235293963, "TOZINAMERAN": 2.7996479110268413}
\ No newline at end of file
+{"BUPRENORPHINE": 27.783480283499557, "ROTATEQ": 769.410623990887, "null": 0.4250694734353579}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6237.json
index 12878d878f9..e63f53f665f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6237.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6237.json
@@ -1 +1 @@
-{"null": 2.992703786062721}
\ No newline at end of file
+{"BEXSERO": 296.64694850554986, "COMIRNATY": 0.2942649417064585, "NIMENRIX": 69.99738985663316, "PREVENAR": 191.88067974129405, "ROTATEQ": 104.53136654764334, "SUBOXONE": 17.595149349726622, "TOZINAMERAN": 2.183323206743089, "null": 0.815471829526792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6238.json
index 6cd1dbe555e..ea5fbf9ca05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6238.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6238.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0414852998944526}
\ No newline at end of file
+{"ABILIFY": 6.192199923987996, "APIDRA": 2.523328031849173, "AVANDIA": 0.9628590605383218, "BRILIQUE": 6.458585299641441, "CHAMPIX": 3.2579505493089065, "CLOPIDOGREL": 1.679216261998762, "COMIRNATY": 0.444527129151243, "DAPAGLIFLOZIN": 14.08792876526469, "ELIQUIS": 4.043177878317358, "ENTRESTO": 2.5990211841000885, "EXFORGE": 22.452804960152772, "FORSTEO": 2.76975931127729, "FORXIGA": 2.1453026938640214, "HUMALOG": 2.0354744103988613, "JANUMET": 1.864884820840454, "JANUVIA": 1.5129454393217563, "JARDIANCE": 1.33509766923519, "LANTUS": 4.60509320735576, "MICARDIS": 5.08994259095519, "PLAVIX": 0.8634348291508124, "RASILEZ": 7.0628793897563735, "SIMPONI": 1.9139247173567369, "SPIKEVAX": 0.1546252982692959, "STELARA": 1.5235404361099334, "SUTENT": 1.5851821473961587, "TASIGNA": 5.290067773914355, "TOZINAMERAN": 0.1894582019882642, "VALSARTAN": 9.34408773644059, "VAXZEVRIA": 0.395478580324386, "VIAGRA": 5.120376813198256, "VOTRIENT": 1.239375124034452, "XELJANZ": 1.0650966152268504, "null": 1.5767076083540228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6239.json
index 1df759f516f..f61754ef5f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6239.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6239.json
@@ -1 +1 @@
-{"KEYTRUDA": 96.00996264380446}
\ No newline at end of file
+{"XELJANZ": 9.527764715352854, "null": 0.4711205340009194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/624.json
index 5553a500ddd..0867d3194b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/624.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/624.json
@@ -1 +1 @@
-{"QUTENZA": 85.15413995213785, "null": 9.833986126933397}
\ No newline at end of file
+{"COMIRNATY": 0.4787292915940387, "null": 1.0233407588825978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6240.json
index 32a04334162..e69f1a774cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6240.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6240.json
@@ -1 +1 @@
-{"COMIRNATY": 2.687666997909171}
\ No newline at end of file
+{"PEGASYS": 5.59189523804532, "null": 0.9632132309199268}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6241.json
index 7d544ed2ded..880b71c3be8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6241.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6241.json
@@ -1 +1 @@
-{"CYTARABINE": 200.66396200307184}
\ No newline at end of file
+{"null": 0.3553047315024529}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6242.json
index fabe3995045..34e168d1e9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6242.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6242.json
@@ -1 +1 @@
-{"ABILIFY": 30.666410785618048, "KEPPRA": 9.593312485670609, "null": 1.0151598592929156}
\ No newline at end of file
+{"ARAVA": 1.2908049676211728, "CICLOSPORIN": 3.911815548207629, "LANTUS": 3.272176082716209, "PEGASYS": 2.1984251621212323, "SIMPONI": 11.379804639644416, "XELJANZ": 8.245967922716813, "null": 0.7624951648913102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6243.json
index 3fbf9e96dbb..9e9c236a99a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6243.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6243.json
@@ -1 +1 @@
-{"FORXIGA": 59.45241731900098, "JARDIANCE": 76.50574730028949}
\ No newline at end of file
+{"ABACAVIR": 8.592568638456447, "ABATACEPT": 5.800129687832262, "ABILIFY": 0.5371256581796828, "ABRAXANE": 1.179070770153816, "ACETAMINOPHEN": 12.566858614856026, "ACLIDINIUM": 1.4781353573796736, "ADALIMUMAB": 3.650476051184509, "ADCETRIS": 1.753449830363653, "ADCIRCA": 0.6377113422989934, "ADVAGRAF": 1.741074679737903, "AFINITOR": 1.0895269102385507, "AIMOVIG": 0.36731888043784, "ALEMTUZUMAB": 3.14992721799683, "ALIMTA": 1.615356327733752, "AMIKACIN": 1.45930346072292, "AMINOSALICYLIC": 0.58955379877035, "ANAKINRA": 3.4848621381477685, "ANTIBIOTICS": 1.485151249425977, "APIDRA": 0.7087138419437122, "APREMILAST": 0.7873765932746342, "APREPITANT": 12.10962647505432, "ARANESP": 1.1562185680971149, "ARAVA": 4.301705899750052, "ARIPIPRAZOLE": 0.2688525275329896, "ARZERRA": 2.7860159443706847, "ASPARAGINASE": 1.8440193664239863, "ATAZANAVIR": 0.3797366129867984, "ATRIPLA": 0.0651255667626856, "AUBAGIO": 1.1390763021344406, "AVANDIA": 0.0843867182159718, "AVASTIN": 1.2697258362339816, 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2.241306870191206, "CELECOXIB": 1.5413931518541424, "CELLCEPT": 2.457563911988345, "CERTOLIZUMAB": 4.241586066944304, "CHAMPIX": 0.1352193025208454, "CHLORHEXIDINE": 18.513057886489943, "CICLOSPORIN": 2.406697085793656, "CIMZIA": 8.483501186320796, "CLADRIBINE": 2.47138830435394, "CLOFARABINE": 3.0705472904990945, "CLOPIDOGREL": 0.0901032761530344, "COBIMETINIB": 1.890437644816898, "COMBIVIR": 0.2469831368128666, "COMIRNATY": 0.1326696225898832, "COSENTYX": 2.866510215904845, "CRESEMBA": 2.545807893418941, "CRIXIVAN": 0.4866059282996983, "CUBICIN": 2.5585112358098008, "CYMBALTA": 0.4597224085826032, "CYTARABINE": 4.226800370417621, "DAPTOMYCIN": 2.912448600450679, "DARATUMUMAB": 1.8385171824601485, "DARZALEX": 3.3786757462722328, "DECITABINE": 4.098102477356623, "DEFITELIO": 2.733157101792721, "DEXAMETHASONE": 2.812112640804961, "DOCETAXEL": 1.281947857108629, "DOXORUBICIN": 3.125625815851294, "DUAKLIR": 10.829053799311415, "DULOXETINE": 0.8050003750856193, "DUPILUMAB": 3.591200522643096, "DUPIXENT": 2.070912006595261, "ELIQUIS": 0.6340531196249513, "EMEND": 0.8841614392717458, "EMPAGLIFLOZIN": 0.5462162199431037, "ENBREL": 3.255496063287737, "ENTRESTO": 0.5360095804823941, "ENTYVIO": 0.8558952095942551, "EPCLUSA": 0.3998551435249775, "ERBITUX": 0.7260255445127117, "ERELZI": 4.572206398133791, "ERLEADA": 0.9835341942761632, "ESBRIET": 1.4803025727008452, "ETANERCEPT": 1.1108946594625608, "EVEROLIMUS": 0.984432813113614, "EVOLTRA": 7.635305913920701, "EXFORGE": 0.3716808759116574, "EXJADE": 3.6702916949729456, "FAMPYRA": 0.6333268413784461, "FASENRA": 1.5837327519990074, "FASLODEX": 0.5445479641694582, "FENTANYL": 1.1034795772049062, "FILGRASTIM": 4.540561875374493, "FIRDAPSE": 0.8392585407285228, "FORSTEO": 0.418504822865627, "FORXIGA": 0.8037296171852394, "FULVESTRANT": 0.5603068104619107, "FYCOMPA": 0.5155195481831757, "GALVUS": 0.7244377400060625, "GANCICLOVIR": 0.8671014327668934, "GARDASIL": 0.8212725415829915, "GAZYVARO": 2.8107207937120644, 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0.6418949805055052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6244.json
index 5a6a6dd2e9a..63a0a7da1ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6244.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6244.json
@@ -1 +1 @@
-{"JARDIANCE": 98.3797168180772}
\ No newline at end of file
+{"CELLCEPT": 54.2060902294955, "CYTARABINE": 57.770230171665865, "null": 0.2186092676899984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6245.json
index d055f6d110f..9941715206c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6245.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6245.json
@@ -1 +1 @@
-{"null": 1.898432931150312}
\ No newline at end of file
+{"CELLCEPT": 20.248774889570942, "XOLAIR": 14.404427049283964, "null": 0.8860118048178214}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6246.json
index 4043785c1b2..bec8b36901d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6246.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6246.json
@@ -1 +1 @@
-{"HYDROCORTISONE": 114.3506496984886, "JARDIANCE": 16.14107894428279, "LEVOFLOXACIN": 20.51317719429193, "SUTENT": 4.011127567991756}
\ No newline at end of file
+{"AXICABTAGENE": 230.9584636332921, "BORTEZOMIB": 35.04204649299487, "BUSULFAN": 55.085857217531455, "CICLOSPORIN": 11.139634661808849, "COMIRNATY": 0.249969930279481, "MYCOPHENOLATE": 50.180485758671146, "PEGINTRON": 14.047558024561583, "SOVALDI": 75.01193638089899, "null": 0.1419477900217589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6247.json
index 7a004a6e21c..1cfbc9f4db2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6247.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6247.json
@@ -1 +1 @@
-{"JARDIANCE": 384.6145035528135}
\ No newline at end of file
+{"ANAKINRA": 6.018386933901725, "COMIRNATY": 3.2398472686648745, "COSENTYX": 4.291457328754646, "GARDASIL": 4.787873710494616, "IBRANCE": 1.1952841719411536, "INFANRIX": 13.65320421868539, "JORVEZA": 534.3324132541065, "MMRVAXPRO": 2.8815443952336954, "SPIKEVAX": 1.3129861640644982, "TWINRIX": 10.590930765391146, "VAXZEVRIA": 0.1441525039796493, "XELJANZ": 1.6009620812803598, "null": 0.4454773429079212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6248.json
index 94b7c7b874d..c6490dabd28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6248.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6248.json
@@ -1 +1 @@
-{"null": 1.741939270774629}
\ No newline at end of file
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6249.json
index 53444b21105..523f18bf14c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6249.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6249.json
@@ -1 +1 @@
-{"ATRIPLA": 3.058779080546067, "SUNITINIB": 259.7499988829635, "TRUVADA": 2.6612894532819773}
\ No newline at end of file
+{"null": 2.1526103969026127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/625.json
index b0537d2dbc0..d47ae502f01 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/625.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/625.json
@@ -1 +1 @@
-{"null": 1.561918659840594}
\ No newline at end of file
+{"APTIVUS": 784.0312787137402, "COMBIVIR": 46.60903777122272, "DESCOVY": 137.58390919058138, "null": 1.600160877462513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6250.json
index 3b40fca7165..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6250.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6250.json
@@ -1 +1 @@
-{"BONVIVA": 60.2509976744506, "CICLOSPORIN": 3.0940854671494176, "FORSTEO": 4.84510271618761, "SIMPONI": 3.2935843976316392, "STELARA": 7.815516190968091, "SUTENT": 1.5110139332076649}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6251.json
index 8287f954560..bdc815bf95d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6251.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6251.json
@@ -1 +1 @@
-{"AVAMYS": 16.534827696977914, "null": 1.3339606397346768}
\ No newline at end of file
+{"COMIRNATY": 1.4141769582735424, "CYMBALTA": 1.0870357061530709, "GARDASIL": 21.47945737499857, "SIMPONI": 2.305987147540465, "SPIKEVAX": 0.527161229836005, "TOZINAMERAN": 1.2477069156917049, "VAXZEVRIA": 0.6542326771464039, "XOLAIR": 3.316866878219124, "null": 0.862649982132895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6252.json
index fa637f0c9f5..1cbdcf249b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6252.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6252.json
@@ -1 +1 @@
-{"COMIRNATY": 2.1620430088028515}
\ No newline at end of file
+{"ALIMTA": 9.738364710619626, "CICLOSPORIN": 3.4873675002202438, "COMIRNATY": 0.1169469315899701, "KEYTRUDA": 5.131392178611103, "OPDIVO": 7.630901397794385, "ROACTEMRA": 15.444995478560044, "SIMPONI": 7.14631143625652, "null": 0.6250143062474355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6253.json
index 2e82a9f4822..80bd3c4a9ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6253.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6253.json
@@ -1 +1 @@
-{"ELIQUIS": 11.159269012890167, "PLAVIX": 11.850185208903696, "null": 1.0780555506800118}
\ No newline at end of file
+{"COMIRNATY": 1.1387581343296962}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6254.json
index 05c95a7779b..1b2a0cf4b70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6254.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6254.json
@@ -1 +1 @@
-{"VAXZEVRIA": 2.121937026479123}
\ No newline at end of file
+{"null": 0.7926968853379056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6255.json
index abd9c33c0b4..34752f919b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6255.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6255.json
@@ -1 +1 @@
-{"null": 2.158702033383775}
\ No newline at end of file
+{"AMBRISENTAN": 479.62612411042807, "APIXABAN": 219.76731271539452, "CLOPIDOGREL": 7.588603046351393, "LYRICA": 26.16378059523933, "null": 0.2083924928186715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6256.json
index f346ece0cf3..313a8a66b99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6256.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6256.json
@@ -1 +1 @@
-{"ALIMTA": 2.177206815011948, "AYVAKYT": 267.8413402999365, "BUDESONIDE": 2.350837245469499, "GLIVEC": 10.545992373431394, "HUMIRA": 1.1324104612947243, "IBUPROFEN": 3.1914461391077844, "IMATINIB": 9.42145148794145, "LYRICA": 1.1498046715518222, "RASILEZ": 7.242809684882715, "SUTENT": 4.995571697315627, "TASIGNA": 2.576622043072833, "XOLAIR": 1.64690761392896, "null": 2.712119060780732}
\ No newline at end of file
+{"null": 0.7011289212253213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6257.json
index b5aad59d828..9c21761c4fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6257.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6257.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2852573834904724, "VAXZEVRIA": 1.0563833387682946}
\ No newline at end of file
+{"null": 0.5610331033905649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6258.json
index 472c4eb7051..3621b8cd6fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6258.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6258.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1725463325844527, "DEXAMETHASONE": 1.3766574208935904, "ENTECAVIR": 21.459340586837158, "ENTRESTO": 1.135380293565042, "MMRVAXPRO": 1.2286912760618982, "NIMENRIX": 3.744682457915451, "SUTENT": 1.2010748795151351, "TAMIFLU": 2.1614824500275764, "TOZINAMERAN": 2.263773396195595, "XOLAIR": 1.01517561758835, "null": 1.7467128798454217}
\ No newline at end of file
+{"AZTREONAM": 112.58805987505896, "CAYSTON": 212.1742150583465, "KAFTRIO": 108.18848405906286, "KALYDECO": 1090.7775353011405, "LAMIRA": 159.55301259006828, "ORKAMBI": 2780.692803587542, "null": 0.8708384636785793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6259.json
index 1457fcdb34b..63be1d96f72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6259.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6259.json
@@ -1 +1 @@
-{"VFEND": 30.14666225107935, "VORICONAZOLE": 2483.749219642236}
\ No newline at end of file
+{"STELARA": 14.211824531418817, "null": 0.6597254716059914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/626.json
index 7c4fdfbde97..d373e652b85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/626.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/626.json
@@ -1 +1 @@
-{"null": 2.2142953271576955}
\ No newline at end of file
+{"ADCIRCA": 14.896472493686606, "APROVEL": 11.412858478747223, "AVANDIA": 3.6539815259801465, "BUDESONIDE": 1.7175031034804762, "CICLOSPORIN": 3.898850099123142, "CLOPIDOGREL": 1.5719921821615608, "COMIRNATY": 0.2426690155904405, "ELIQUIS": 4.1900975833659215, "HUMALOG": 3.563080950410208, "JANUMET": 2.5291117362540247, "LANTUS": 1.3988848946141534, "LYRICA": 2.050026813316709, "OMALIZUMAB": 4.40249358657242, "PEGASYS": 1.1961031728380358, "PEGINTRON": 1.9229350476312572, "PLAVIX": 2.7827109367542846, "ROACTEMRA": 3.273253783625714, "SPIKEVAX": 0.1541484175006124, "STELARA": 1.4684495615825612, "SUTENT": 0.7890940326102316, "TOZINAMERAN": 0.517474938989391, "TRELEGY": 5.565974973451828, "VAXZEVRIA": 0.1736536866848098, "VIAGRA": 6.2984258876672055, "XELJANZ": 0.95967449608876, "ZOSTAVAX": 1.212863829534835, "null": 1.572922059894847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6260.json
index c03b2c15feb..8023dac8356 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6260.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6260.json
@@ -1 +1 @@
-{"null": 2.279485601685458}
\ No newline at end of file
+{"null": 0.8071462026075795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6261.json
index 15836c7d4d5..91ef7e6fc4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6261.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6261.json
@@ -1 +1 @@
-{"null": 3.0938723142390154}
\ No newline at end of file
+{"CLOPIDOGREL": 20.87724680229958, "null": 1.703387479893112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6262.json
index cb0730324ab..502f98a6802 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6262.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6262.json
@@ -1 +1 @@
-{"CICLOSPORIN": 20.616843425485712}
\ No newline at end of file
+{"ABILIFY": 10.178780903240384, "BUPRENORPHINE": 7.951653155231626, "COMIRNATY": 0.814434573460777, "GARDASIL": 8.486809905560957, "PEGASYS": 2.906384737347863, "SPIKEVAX": 0.3582158826078574, "STELARA": 3.1802325151009683, "TOZINAMERAN": 0.9817650318046506, "VAXZEVRIA": 0.265031914127679, "null": 1.3523710385105805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6263.json
index 2755daefdc8..521ff578e8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6263.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6263.json
@@ -1 +1 @@
-{"AVANDIA": 3.595742729762115, "BOSULIF": 8.180599131483248, "BOSUTINIB": 46.18491893600885, "CLOPIDOGREL": 2.483426744165686, "ELIQUIS": 2.7651290733313423, "FORXIGA": 3.6371742611429374, "HUMALOG": 1.478009552025381, "ICLUSIG": 69.0623561839334, "IMATINIB": 15.406600670784329, "JANUMET": 2.347033230075813, "JARDIANCE": 1.9339500045956644, "NILOTINIB": 250.70679987256895, "PLAVIX": 4.547100305217328, "SPRYCEL": 5.747034098392515, "TASIGNA": 239.31663393931655, "ZOSTAVAX": 3.865087411301512}
\ No newline at end of file
+{"COMIRNATY": 0.8535139063023205, "GARDASIL": 7.587488265601696, "null": 1.1678727281780183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6264.json
index 140bd86a3b0..2434ab3a407 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6264.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6264.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 7.063615947994778, "CLOPIDOGREL": 2.3722351744245707, "ELIQUIS": 2.096004366600632, "ENOXAPARIN": 14.159270387944304, "HUMALOG": 3.456858238818632, "ICLUSIG": 12.879366070197138, "JARDIANCE": 4.523240552508843, "LANTUS": 1.4739396374032887, "NILOTINIB": 46.78502574437142, "PLAVIX": 6.299287492240356, "TASIGNA": 55.40814471022747, "XARELTO": 11.790499690839017}
\ No newline at end of file
+{"null": 5.059784834593736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6265.json
index 84d4e3fc9bd..cdd48645cf8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6265.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6265.json
@@ -1 +1 @@
-{"ICLUSIG": 62.84336830361444, "NILOTINIB": 363.3881513720295, "TASIGNA": 186.3985226001778}
\ No newline at end of file
+{"null": 0.3992861189850491}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6266.json
index 5cfb4f03414..1d1bab638ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6266.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6266.json
@@ -1 +1 @@
-{"AERIUS": 17.77187774494437, "CLOPIDOGREL": 2.864715582791518, "ELIQUIS": 3.649051938326524, "FASLODEX": 6.618018402267256, "ICLUSIG": 11.320424895315822, "NOVOSEVEN": 137.68330558704656, "STELARA": 2.295140996474106, "TASIGNA": 10.042240319792011, "VAXZEVRIA": 2.872970538658464}
\ No newline at end of file
+{"ABATACEPT": 6.3011925495727175, "ACLASTA": 3.3919642194432917, "ACLIDINIUM": 1.687252823041063, "ADALIMUMAB": 6.237708263367304, "AFINITOR": 1.3566826532630392, "AIMOVIG": 0.4582767545439479, "ALDARA": 7.306293880697874, "ALEMTUZUMAB": 0.4395517939056629, "ALIMTA": 0.6265837589898577, "AMGEVITA": 19.847935195390995, "AMIKACIN": 1.8466465749453147, "AMINOSALICYLIC": 0.461358851418554, "ANAKINRA": 1.2061938382899575, "APIDRA": 0.3595612039990295, "APIXABAN": 0.3619954924756572, "APREMILAST": 6.197968463667811, "ARANESP": 0.2487423261190129, "ARAVA": 1.6737448744177734, "ARIXTRA": 2.6184451665575184, "ATRIPLA": 0.0297736933785267, "AUBAGIO": 0.6098129382981173, "AVASTIN": 0.4074596520563913, "AYESURBY": 114.6342502272756, "AZATHIOPRINE": 6.3859530835892695, "BASILIXIMAB": 1.7372092059926316, "BELIMUMAB": 7.592193268642691, "BENLYSTA": 3.0253871733748467, "BENRALIZUMAB": 3.1059403214309613, "BEOVU": 1.0577852873241556, "BETAFERON": 0.9551826011202024, "BEVACIZUMAB": 0.6099752286290351, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6267.json
index e740780654d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6267.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6267.json
@@ -1 +1 @@
-{"COMIRNATY": 2.2206821637244043, "SPIKEVAX": 1.2578989659648483, "VAXZEVRIA": 3.2247585286041778}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6268.json
index 3eca669bce6..323bc0c6448 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6268.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6268.json
@@ -1 +1 @@
-{"AIMOVIG": 1.8634797818202544, "APROVEL": 1.765669075652618, "COAPROVEL": 1.8668826569477863, "COMIRNATY": 1.374101167453205, "COVID19": 3.0870732450579337, "EDOXABAN": 18.66806084300031, "FAMPYRA": 1.02289244833481, "FIRDAPSE": 5.685801884561881, "FLEBOGAMMA": 1.969869594625232, "GARDASIL": 4.1912639708944885, "HYDROCORTISONE": 3.55626541674488, "IRBESARTAN": 1.2507503062703988, "KALETRA": 1.1669091644239469, "KIOVIG": 3.158261590466468, "LOPINAVIR": 6.4214541091289385, "MICARDIS": 1.1204137861193264, "PROPRANOLOL": 3.4220670752125355, "SPIKEVAX": 1.1322702660679882, "TOZINAMERAN": 1.9761391011657568, "TWINRIX": 1.7100734707233871, "VALSARTAN": 1.9002037237168763, "VAXZEVRIA": 2.170845432192784}
\ No newline at end of file
+{"COMIRNATY": 0.4972471818645569, "null": 0.578691898322137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6269.json
index 35db3402bcc..121201734a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6269.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6269.json
@@ -1 +1 @@
-{"ELIQUIS": 6.739992436345964}
\ No newline at end of file
+{"ADALIMUMAB": 0.8014188260935, "AMINOSALICYLIC": 10.577831970737904, "ARAVA": 0.9417091052252984, "AZATHIOPRINE": 19.92363115110685, "BUDESONIDE": 2.0864242281332905, "CICLOSPORIN": 1.655867848982325, "CIMZIA": 3.71221539379242, "COMIRNATY": 0.3224848118466689, "COSENTYX": 64.27694836700651, "DAXAS": 167.861493551287, "ENBREL": 1.5399471706039496, "ENTYVIO": 22.875901005054715, "GARDASIL": 2.12177509232735, "HUMIRA": 6.680591347388483, "RINVOQ": 4.310297131766532, "SIMPONI": 2.430582611242476, "SPIKEVAX": 0.2300045771640326, "STELARA": 11.140692687452509, "TOZINAMERAN": 0.3929082696556111, "VAXZEVRIA": 0.0990883427476816, "XELJANZ": 2.799091818244326, "null": 0.7255009704058654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/627.json
index a1c4e71e69f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/627.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/627.json
@@ -1 +1 @@
-{"null": 6.966216456354185}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6270.json
index dfa86255c88..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6270.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6270.json
@@ -1 +1 @@
-{"ALIMTA": 3.4355198825332045, "BUPRENORPHINE": 2.1026600225188123, "CABOMETYX": 4.066078301618449, "CLOPIDOGREL": 1.172048969442765, "ELIQUIS": 1.367151081791253, "EMPAGLIFLOZIN": 22.54036167742105, "ICLUSIG": 6.444370132216057, "KALETRA": 4.92907737695531, "LAMIVUDINE": 9.199746292940432, "NEXAVAR": 1.122104618397474, "NOVOSEVEN": 55.96816978497376, "OPTIMARK": 3.960055522563656, "PEMETREXED": 11.482248470918138, "PLAVIX": 1.1594604441814909, "ROACTEMRA": 7.70196228660544, "TASIGNA": 10.61232327409314, "null": 1.2997932824986362}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6271.json
index a6a6867be73..0c9775254b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6271.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6271.json
@@ -1 +1 @@
-{"ASPARAGINASE": 13.408992819907525, "BLINATUMOMAB": 363.0720385040647, "DABRAFENIB": 45.268081504696575, "NORVIR": 36.550546887176736, "PEGASYS": 2.9221716322032134, "THALIDOMIDE": 68.0896975870547}
\ No newline at end of file
+{"null": 0.7743032315660294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6272.json
index 0b6851790d9..a7e49eae158 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6272.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6272.json
@@ -1 +1 @@
-{"FENTANYL": 8.878903296595146, "LEVOFLOXACIN": 10.267746259537336, "null": 1.589144650542983}
\ No newline at end of file
+{"ABATACEPT": 3.10161202885721, "ADALIMUMAB": 1.7426152083815083, "AMIKACIN": 14.389638833673551, "ARAVA": 1.752841345609722, "AZATHIOPRINE": 4.681657257814806, "CIMZIA": 4.7006781087799325, "CLOPIDOGREL": 1.4024859411151682, "COMIRNATY": 1.258279920302092, "COSENTYX": 2.503035568645474, "CYTARABINE": 4.390950891122365, "ENVARSUS": 179.42922398324947, "FAMPYRA": 5.805344025877565, "HUMIRA": 4.672471322094531, "JARDIANCE": 2.2443136919681925, "KEYTRUDA": 1.6596422540822806, "KYMRIAH": 7.161187893129215, "RINVOQ": 3.770315460831331, "SPIKEVAX": 0.6785908569428186, "STELARA": 0.9257556844746916, "TOZINAMERAN": 0.8415297864776187, "VAXZEVRIA": 0.3015969810852598, "XELJANZ": 4.3275354217436455, "null": 0.4891919901348929}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6273.json
index 0c05fb3100f..8d7b2827503 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6273.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6273.json
@@ -1 +1 @@
-{"COMIRNATY": 1.216077043941412, "VAXZEVRIA": 1.289471071922838}
\ No newline at end of file
+{"ADALIMUMAB": 1.755220540394937, "BUPRENORPHINE": 13.249911973109176, "COMIRNATY": 1.1851724661118797, "COSENTYX": 16.03874872813674, "EXFORGE": 12.254302999833044, "SPIKEVAX": 1.1717991591428032, "TOZINAMERAN": 1.7320360343037275, "VAXZEVRIA": 1.1325359576080538, "null": 0.2905531431238334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6274.json
index bbdbb3c7a38..1c93d877847 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6274.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6274.json
@@ -1 +1 @@
-{"COMIRNATY": 2.5915127334107493}
\ No newline at end of file
+{"null": 1.174616373878293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6275.json
index 9139725a0cd..f24eabd7ba7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6275.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6275.json
@@ -1 +1 @@
-{"GARDASIL": 8.092680980914258}
\ No newline at end of file
+{"ABASAGLAR": 0.8268078479219924, "ABILIFY": 0.1776785915648515, "ACTOS": 0.5830377954262737, "ADALIMUMAB": 0.0224883687012413, "ADEMPAS": 1.2060706977797049, "AFINITOR": 0.413090061752434, "AIMOVIG": 0.3214867031450853, "ALDARA": 0.7364302687889756, "ALEMTUZUMAB": 0.5997436406436367, "ALIMTA": 0.1152872480765668, "AMBRISENTAN": 1.1566427827968857, "ANAKINRA": 0.2318613365521077, "ANORO": 0.3698004306189768, "ANTIBIOTICS": 1.1514112226514606, "APIXABAN": 1.5314213387326872, "ARANESP": 0.0919854413256607, "ARAVA": 0.1206754570637723, "ASPARAGINASE": 0.1768386005348819, "AUBAGIO": 0.6132496199386643, "AVAMYS": 0.5212440869687209, "AVASTIN": 0.0826978075373152, "AXICABTAGENE": 1.5057697518850115, "AZATHIOPRINE": 0.6030441633773589, "BELIMUMAB": 0.94825432777328, "BENLYSTA": 2.990435487683974, "BENRALIZUMAB": 1.7933273068869244, "BETAFERON": 0.6855054437333459, "BEVACIZUMAB": 0.1001151060471866, "BONVIVA": 0.8263694288197014, "BOSULIF": 0.4654279241934538, "BRINTELLIX": 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2.5374097544710894, "XOLAIR": 1.745148655595879, "XTANDI": 0.3522568459175003, "XYREM": 0.2602820085178895, "ZINBRYTA": 1.8976420441066304, "ZOSTAVAX": 0.3540418694862163, "ZYPREXA": 0.0814983848210606, "null": 0.265952476745501}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6276.json
index d102470f5aa..20b78f33dcd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6276.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6276.json
@@ -1 +1 @@
-{"LOPINAVIR": 462.791873582706}
\ No newline at end of file
+{"SPIKEVAX": 28.77409830629225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6277.json
index 21c45e07d11..fb18ee37047 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6277.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6277.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 14.16113331860664, "CYMBALTA": 2.7841462594215542, "DEXAMETHASONE": 6.050556624600754, "KALETRA": 10.272232817797898, "PEGASYS": 2.0087261054667325, "TELMISARTAN": 69.99693825383892, "null": 1.0351893029852413}
\ No newline at end of file
+{"TAMIFLU": 49.66379759870595, "null": 0.3554471913211595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6278.json
index 151d8a549bf..8dc872fa058 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6278.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6278.json
@@ -1 +1 @@
-{"ABRAXANE": 14.671557522902848, "ADCETRIS": 28.956403504266547, "ALIMTA": 2.454926443280172, "AMINOSALICYLIC": 2.826441540427532, "ASPARAGINASE": 3.4635638025119397, "ATAZANAVIR": 5.237790466362527, "AUBAGIO": 1.670466549830655, "AVASTIN": 10.619619192454635, "BEVACIZUMAB": 9.75463611979253, "BLINATUMOMAB": 33.80432070279049, "BORTEZOMIB": 26.60243216122796, "CAPECITABINE": 7.494455365201925, "CICLOSPORIN": 1.0533605321137582, "CYTARABINE": 6.633860156241059, "DABRAFENIB": 10.448255366274385, "DARUNAVIR": 10.5265978137022, "DARZALEX": 5.617823365857957, "DEXAMETHASONE": 4.819338183055592, "DOCETAXEL": 4.271454127678446, "ERBITUX": 16.333154170616254, "EVEROLIMUS": 16.274647361266226, "HALAVEN": 11.64383512958491, "HERCEPTIN": 3.854672781068957, "IRINOTECAN": 24.741762827475803, "KEYTRUDA": 1.8103474774870283, "NORVIR": 7.426022793299137, "OPDIVO": 4.0890285886855136, "PACLITAXEL": 12.865449832205602, "PANITUMUMAB": 38.809223758920666, "PEGASYS": 1.1084111607696563, "TELMISARTAN": 15.417019349574757, "THALIDOMIDE": 86.03693107542922, "VELCADE": 29.22554974512547, "null": 1.4320888385304582}
\ No newline at end of file
+{"SPIKEVAX": 27.86046440444297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6279.json
index de3444eac86..498f5412b4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6279.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6279.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.3138754779019717, "ABATACEPT": 4.307888223523494, "ADALIMUMAB": 1.1822395569452555, "ADCIRCA": 3.807379056808041, "ADEMPAS": 1.750514923716723, "ADVATE": 1.1915643315273952, "ALBIGLUTIDE": 6.617030366243652, "ALISKIREN": 1.8048990535902745, "AMBRISENTAN": 2.21963515297341, "APREMILAST": 3.2941311668734694, "ARAVA": 2.933660418066702, "BENLYSTA": 1.7116132244956437, "BETMIGA": 1.046718846643052, "BEXSERO": 1.3325431648506247, "BONVIVA": 1.0493940786154103, "BOSULIF": 1.1745048552383943, "BRUKINSA": 1.4742625060257268, "CELECOXIB": 1.3829306672629464, "CHLORHEXIDINE": 11.333138761845948, "CIMZIA": 4.44986124933645, "CONTRAST": 1.5881941268315083, "COSENTYX": 1.8850856201553672, "COVID19": 1.580426421952454, "DUPIXENT": 1.3944563096076996, "ELIQUIS": 1.197654191016075, "ENBREL": 3.373696996181063, "ENOXAPARIN": 1.102628724536861, "ENTRESTO": 1.3783121706544113, "ERELZI": 3.7778105478182895, "EVENITY": 1.1848822779896353, "EVISTA": 2.093672755562276, "EXFORGE": 3.1783725195878687, "FLUCELVAX": 2.372252398173686, "FORSTEO": 1.9578288845090608, "HIZENTRA": 1.6448583495594251, "HUMIRA": 2.487884987268813, "HYDROCHLOROTHIAZIDE": 1.161976053987538, "IBRANCE": 1.3652372403110895, "IDACIO": 2.094863910594089, "IRON": 1.244838052164453, "KOVALTRY": 2.661680718730477, "LEFLUNOMIDE": 2.8898103802668995, "LIXIANA": 1.3811686324087928, "LUPKYNIS": 1.4423200553128317, "LYRICA": 1.7576239210084816, "MACITENTAN": 2.4832690818304566, "MENVEO": 2.255393630937274, "METHOTREXATE": 1.2414999862212357, "MICARDIS": 1.277195286637504, "MICARDISPLUS": 1.0315900911305087, "MIRABEGRON": 1.2515067862737002, "MOVYMIA": 2.0284355272018013, "NIMENRIX": 1.0585488796660156, "NINLARO": 3.234383834447606, "NOT": 1.006442579077779, "NUCALA": 1.2252623576373516, "OCRELIZUMAB": 1.215991806636508, "OMALIZUMAB": 1.1902911336121818, "OPSUMIT": 2.1505224748492897, "OPTIMARK": 1.8542483034528208, "OXYBUTYNIN": 1.2403648069346824, "PROLIA": 1.944975325018649, "PROTOPIC": 1.8444180701476085, "RAPAMUNE": 1.427689568836395, "RASILEZ": 1.3453194437641498, "REVATIO": 1.8751621193827164, "REVLIMID": 1.1113905039014338, "RINVOQ": 1.79736577871643, "ROACTEMRA": 1.2858020910059194, "RUBRACA": 1.1770611945033225, "SHINGRIX": 2.3111403842813765, "SIMPONI": 1.3047107825168105, "SOMAVERT": 2.480743531082287, "SPIKEVAX": 1.386354251823135, "SPIRONOLACTONE": 1.0059284357455345, "SUTENT": 1.2993699049977487, "TOUJEO": 1.1993227972795386, "TOZINAMERAN": 2.237638262342473, "TWINRIX": 1.0498965036547372, "VALSARTAN": 2.191571950742943, "XALKORI": 2.2426008614593327, "XELJANZ": 2.7673379784818533, "XIAPEX": 6.27675194293081, "XOLAIR": 1.4484719139633155, "XTANDI": 2.492510051591361, "ZELBORAF": 1.1004274344187908}
\ No newline at end of file
+{"ABILIFY": 0.0330587219765135, "ADEMPAS": 0.2243480289981421, "AFINITOR": 0.1671700904108634, "AIMOVIG": 0.7106238660899129, "ALDARA": 6.745198237156695, "ALEMTUZUMAB": 0.1614751709736996, "AMBRISENTAN": 0.3978146003586985, "ANORO": 0.1475026030395407, "APROVEL": 0.174990715029165, "ARANESP": 0.0789602288572808, "ARAVA": 0.0759015121528653, "AUBAGIO": 0.4192113583966567, "AVANDIA": 0.03409638435367, "AVASTIN": 0.1984439279610388, "AVONEX": 2.1282097580792385, "BEDAQUILINE": 0.1076432717268315, "BENLYSTA": 0.3792947336461115, "BESREMI": 4.603300738466763, "BETAFERON": 5.200479261848722, "BEXSERO": 0.3777553798235782, "BIKTARVY": 0.0804653321862878, "BOCEPREVIR": 1.082941383370084, "BONVIVA": 3.49833481901078, "BOTULINUM": 1.6945762670249316, "BRINTELLIX": 0.8433241075277176, "BRIVIACT": 0.2122726460209157, "BUDESONIDE": 0.1221355547169216, "BUPRENORPHINE": 0.0622264599793771, "BYDUREON": 1.0303250740117122, "BYETTA": 0.0461507509274881, "CELLCEPT": 0.0879401325452547, "CELSENTRI": 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0.4605701027002244, "FLUCELVAX": 1.5869961417043676, "FORSTEO": 0.1189925795231372, "FORXIGA": 0.1592281873030437, "GARDASIL": 0.8278881412521288, "GLYCOPYRRONIUM": 0.6179879010169891, "HERCEPTIN": 0.2486744265331089, "HIZENTRA": 0.8882388638693391, "HUMALOG": 0.097273196188627, "HUMAN": 0.1065120129341909, "HUMIRA": 0.2126142286486882, "HYDROCORTISONE": 0.7667223924153656, "HYQVIA": 0.5761963058792998, "IBRANCE": 0.1318214465936843, "IBUPROFEN": 0.1866346500015328, "IMIQUIMOD": 2.977177588933304, "INCIVO": 0.5885874407334217, "INFERGEN": 2.3352455434726824, "INFLIXIMAB": 0.364831070554011, "INTERFERON": 1.6698120677224937, "INTRONA": 1.2275272601220228, "IRBESARTAN": 0.1387006507861517, "ISENTRESS": 0.170975843638509, "JANUMET": 0.0745639957771285, "JANUVIA": 0.0525866617446133, "JARDIANCE": 0.1210807203631443, "JCOVDEN": 1.032610120370031, "KAFTRIO": 0.144605846258761, "KALETRA": 0.061348428048625, "KEPPRA": 0.0537756748304842, "KESIMPTA": 6.522479623162985, "KEYTRUDA": 0.0362282973083637, "KIOVIG": 0.5449797617636156, "LANTUS": 0.0464433937667674, "LATUDA": 0.0941487748086318, "LEMTRADA": 0.2244982616470521, "LEVETIRACETAM": 0.0369733839592737, "LYRICA": 0.1108404611099387, "MAVENCLAD": 0.606698381212198, "MEKINIST": 0.2442032761510874, "MENVEO": 0.2806433774367911, "MEPOLIZUMAB": 0.4206767589024194, "METHOTREXATE": 0.1342313906387829, "MICARDIS": 0.1989689761373143, "MMRVAXPRO": 0.3454432563792277, "MODERNA": 5.07894610531853, "NAGLAZYME": 0.3001036584842242, "NEULASTA": 0.5640408618427022, "NEXAVAR": 0.0874188079476585, "NIMENRIX": 1.1359581729500312, "NPLATE": 0.0877362982393406, "NUCALA": 0.2793211668763225, "OCRELIZUMAB": 2.081867476320613, "OFEV": 0.1154919347511047, "OLANZAPINE": 0.0644902575097521, "OLYSIO": 0.3043104676216986, "OMALIZUMAB": 0.4867919914380537, "OPSUMIT": 0.249072848029269, "ORKAMBI": 0.284017220539583, "PANTOPRAZOLE": 0.1560789908304282, "PEGASYS": 1.9477822197913448, "PEGINTERFERON": 1.3766685742326203, "PEGINTRON": 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"VICTOZA": 0.0667292069662594, "VIRAMUNE": 0.4604187213487078, "XELJANZ": 0.2714047206136185, "XOLAIR": 0.7333767159318221, "XTANDI": 0.0972125568275499, "ZEPATIER": 0.4692683890951164, "ZIAGEN": 1.1986444232209987, "ZOSTAVAX": 0.2979401486413552, "ZYCLARA": 4.690176277945901, "ZYPREXA": 0.0696652324305025, "null": 0.1321915290964175}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/628.json
index 3010edbfd8d..d843d6cc544 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/628.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/628.json
@@ -1 +1 @@
-{"ALDARA": 34.2725169819962, "AMELUZ": 78.91465391185146, "BUPRENORPHINE": 8.080385395562752, "EVRA": 76.49688124651175, "KENTERA": 266.6039195958152, "QUTENZA": 79.07628640548619, "null": 8.857872411016452}
\ No newline at end of file
+{"TICAGRELOR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6280.json
index d0aa7db24ea..3e879691d5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6280.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6280.json
@@ -1 +1 @@
-{"AVANDAMET": 5.234960823364357, "AVANDIA": 6.756682927408639, "BOSUTINIB": 17.0810309108648, "BYETTA": 1.8338809799024065, "COMIRNATY": 1.5116791380296024, "GARDASIL": 3.770380738095266, "HUMALOG": 2.024454419421392, "ICLUSIG": 4.207833105397713, "JANUMET": 1.4607189139996646, "JANUVIA": 2.458773352660824, "JARDIANCE": 1.3968007792011197, "LANTUS": 1.0281885216109623, "NILOTINIB": 22.549931040880217, "OPTIMARK": 1.4501017490113175, "SHINGRIX": 3.63445877473144, "SPRYCEL": 1.3172413735135555, "TASIGNA": 25.99487833468264, "TWINRIX": 5.822038149731333, "VAXZEVRIA": 3.805579469567367, "VIAGRA": 1.5598722302096528, "ZOSTAVAX": 3.314793763181421}
\ No newline at end of file
+{"SPIKEVAX": 10.432885952215912}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6281.json
index a85519b7fce..95acaec0e85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6281.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6281.json
@@ -1 +1 @@
-{"ABATACEPT": 6.9820024103254, "ADALIMUMAB": 22.15822582565768, "APREMILAST": 21.312116555646824, "ARAVA": 1.1536777208744964, "BYETTA": 2.447988307281232, "CIMZIA": 2.908719501866156, "COSENTYX": 5.795138036411785, "ELIQUIS": 1.9463780467037912, "HYDROCORTISONE": 6.344541821465205, "VAXZEVRIA": 1.0198818788294144, "ZOSTAVAX": 3.5864718923126166, "ZYPREXA": 2.631285683951333}
\ No newline at end of file
+{"ELIQUIS": 2.099134406917504, "INFLIXIMAB": 47.003772984888606, "SUTENT": 1.779311357942241, "null": 1.5741770363863663}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6282.json
index 61ddbdbf5aa..019342fdabb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6282.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6282.json
@@ -1 +1 @@
-{"null": 1.155800322825551}
\ No newline at end of file
+{"null": 0.4894537929896228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6283.json
index 976eface428..79d36226896 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6283.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6283.json
@@ -1 +1 @@
-{"null": 2.7324561440655404}
\ No newline at end of file
+{"null": 1.529514383481331}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6284.json
index d69d58c5b80..211204ebea1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6284.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6284.json
@@ -1 +1 @@
-{"CIMZIA": 10.018949033417709, "JARDIANCE": 9.23377281705044}
\ No newline at end of file
+{"ABACAVIR": 24.46678274043601, "ABATACEPT": 8.088783008785661, "ACETAMINOPHEN": 21.988815956056705, "ACLASTA": 3.4797199909375998, "ADALIMUMAB": 17.138224799338758, "AGALSIDASE": 17.317630442395497, "ALEMTUZUMAB": 0.6367070582031673, "ALIMTA": 0.5513848975315303, "AMINOSALICYLIC": 9.85698474658934, "ANAKINRA": 0.9986872146659592, "APIXABAN": 0.2220131006827582, "APREMILAST": 13.742923219633482, "APREPITANT": 19.524010325729176, "ARAVA": 14.730530878140348, "ARZERRA": 14.8457164984654, "ATEZOLIZUMAB": 5.881201339089353, "AVAMYS": 8.698014700821338, "AVASTIN": 1.6760499492751648, "AVELUMAB": 16.322856595610713, "AXITINIB": 1.274109018066598, "AZATHIOPRINE": 1.5648134959571345, "BAVENCIO": 30.263936496241936, "BENLYSTA": 1.933817828000707, "BEVACIZUMAB": 0.6809559482947625, "BORTEZOMIB": 2.0796688567753985, "BOTULINUM": 0.9949667117605724, "BRAFTOVI": 1.0889538874222968, "BUDESONIDE": 11.4179530028121, "CAELYX": 27.69827858036788, "CAPECITABINE": 0.7418943321853737, "CARFILZOMIB": 4.640315916973252, "CELECOXIB": 0.955529022532376, "CELLCEPT": 0.2346102938070337, "CICLOSPORIN": 0.7822066930508645, "CIMZIA": 2.386433018408605, "CINRYZE": 9.204765678981673, "CLOPIDOGREL": 0.0981885134136608, "COMIRNATY": 0.0054279750197833, "COSENTYX": 0.1919175045366313, "CYMBALTA": 0.5342581224550943, "CYTARABINE": 0.2686931028721251, "DARZALEX": 79.28832067209537, "DEXAMETHASONE": 0.7357882165028922, "DOCETAXEL": 1.001293445359982, "DOXORUBICIN": 0.961913585508138, "ENBREL": 5.352965162285789, "ENTYVIO": 2.1929421162686924, "ERBITUX": 8.464936897539623, "ERELZI": 4.337456214834252, "ESOMEPRAZOLE": 0.5543789294971397, "ETANERCEPT": 2.7276886368634887, "FENTANYL": 0.1004890261652656, "FLEBOGAMMA": 14.098299361186882, "GANCICLOVIR": 0.7624207164873082, "GAZYVARO": 46.704607631476414, "HERCEPTIN": 13.78088985863785, "HIZENTRA": 0.3226735363265363, "HUMAN": 2.6265451572171536, "HUMIRA": 1.2714638939168643, "HYDROCORTISONE": 0.5550571006837008, "HYQVIA": 3.3731539142298588, "ILARIS": 19.021352046489564, "INFLIXIMAB": 2.560179316215295, "IPILIMUMAB": 1.5634916457620631, "JEVTANA": 0.6532031394303638, "KEYTRUDA": 1.5450608329815676, "KIOVIG": 6.4666658005341136, "KYMRIAH": 0.8572857146349727, "KYPROLIS": 1.752897046994347, "LEFLUNOMIDE": 1.3920250003540982, "LEMTRADA": 1.742950319002593, "LEVOFLOXACIN": 0.1906768796940285, "MABTHERA": 3.663189675439032, "METHOTREXATE": 2.8620165609026653, "MYCOPHENOLATE": 0.6282528378471162, "NAGLAZYME": 8.652112624932109, "OBINUTUZUMAB": 23.44582970320656, "OCRELIZUMAB": 4.998457308163618, "ONCASPAR": 2.140329760239252, "OPDIVO": 2.671359213541632, "ORENCIA": 5.132780364916249, "PACLITAXEL": 2.0721947443348614, "PEGASYS": 0.0372125990341429, "PEMBROLIZUMAB": 0.8999616855232184, "PERJETA": 22.759051600025884, "PERTUZUMAB": 10.059885656161416, "POTELIGEO": 31.61374002051957, "PREGABALIN": 5.033343155396176, "PRIVIGEN": 4.273712880470028, "REMDESIVIR": 2.0562778267387687, "REMICADE": 22.42866634364605, "RITUXIMAB": 9.144554945194564, "RIXATHON": 32.75428987528744, "ROACTEMRA": 3.829199116227006, "SOLIRIS": 1.0450559248914328, "STELARA": 5.617281987113422, "SYLVANT": 10.35582239423618, "TOCILIZUMAB": 2.570380391443917, "TORISEL": 4.113035691601546, "TRODELVY": 1.5224691187433366, "VAXZEVRIA": 0.0101566129947941, "VECTIBIX": 3.268563738025764, "VEKLURY": 1.5401821512882157, "YERVOY": 1.2766175413971343, "null": 0.3134486218818716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6285.json
index 594143686fc..07699ea9efd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6285.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6285.json
@@ -1 +1 @@
-{"null": 23.340019202682}
\ No newline at end of file
+{"HIZENTRA": 445.6791247779289}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6286.json
index 10008a8b4ac..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6286.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6286.json
@@ -1 +1 @@
-{"ARANESP": 88.78259271561392}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6287.json
index ee1056ae80c..effb4940d66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6287.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6287.json
@@ -1 +1 @@
-{"null": 23.00939142604211}
\ No newline at end of file
+{"HIZENTRA": 454.0912088326572, "HUMAN": 55.14515716546533, "null": 0.4914614527952656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6288.json
index ffbbe132583..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6288.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6288.json
@@ -1 +1 @@
-{"AVASTIN": 52.850759373403775}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6289.json
index e286a1ad834..a8679d087c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6289.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6289.json
@@ -1 +1 @@
-{"null": 7.580088704520082}
\ No newline at end of file
+{"HIZENTRA": 240.0035130832028, "null": 0.6647957300243768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/629.json
index 17a2588dad3..35c05d41dae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/629.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/629.json
@@ -1 +1 @@
-{"AMELUZ": 1764.2703490542085, "null": 4.261048660632532}
\ No newline at end of file
+{"null": 1.0694489479752738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6290.json
index e4b2652f84c..6ed6d3e8c0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6290.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6290.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"OPSUMIT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6291.json
index 16136ad3645..edc5076aa11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6291.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6291.json
@@ -1 +1 @@
-{"null": 1.548528338481882}
\ No newline at end of file
+{"HIZENTRA": 309.60892174152303, "HYQVIA": 409.4329683230082, "IBUPROFEN": 17.165168815656862, "null": 0.7384584494777172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6292.json
index b9dcab5c517..cf5d69ef6ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6292.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6292.json
@@ -1 +1 @@
-{"CIMZIA": 13.94469109812356, "PEGINTRON": 20.86643233759957, "SIMPONI": 41.63369215343048}
\ No newline at end of file
+{"HIZENTRA": 109.1812227315124, "null": 1.6511095342512934}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6293.json
index 6a867100a00..7415b2902e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6293.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6293.json
@@ -1 +1 @@
-{"ALIMTA": 3.129826647901603, "ANIDULAFUNGIN": 33.843766951424854, "ARANESP": 4.300743857641797, "ARIPIPRAZOLE": 1.7535554867481828, "ASPARAGINASE": 2.3044057099609327, "AVASTIN": 23.90244897684604, "AZATHIOPRINE": 1.8433432040878213, "BEDAQUILINE": 3.046480804019243, "BEVACIZUMAB": 3.871864109144701, "CABOMETYX": 1.5409818810017852, "CELLCEPT": 5.079260484300982, "CICLOSPORIN": 3.7985126196202894, "DEXAMETHASONE": 2.48752275553548, "DOCETAXEL": 2.2139518672388983, "ECULIZUMAB": 41.09252560238984, "EMTRICITABINE": 4.682494025458942, "FORSTEO": 1.24256319477173, "HUMIRA": 1.204923040406059, "INCIVO": 1.857309709975416, "IPILIMUMAB": 2.2190722713139697, "IRESSA": 4.753691269167062, "IRINOTECAN": 3.411495994258846, "ISENTRESS": 3.822973430022648, "JAKAVI": 1.3943594102991583, "KALETRA": 1.3702194528252791, "KEYTRUDA": 1.9901213707551408, "LENVIMA": 2.652979241113815, "MEKINIST": 1.1678809105246648, "METHOTREXATE": 1.694434733214748, "MYCOPHENOLATE": 3.214422121006701, "NEXAVAR": 2.4924478670896604, "OLANZAPINE": 1.1444179993014312, "OPDIVO": 2.603082735384791, "PEGINTRON": 2.3135606293766737, "PEMBROLIZUMAB": 1.837943800312371, "REMICADE": 4.537027281568919, "ROACTEMRA": 18.31268717934086, "SOLIRIS": 3.420306724646078, "STELARA": 1.7868707317738992, "STIVARGA": 4.713961807887195, "SUTENT": 2.16712664023413, "TACROLIMUS": 9.178477286389231, "TORISEL": 5.153673278473041, "TRULICITY": 1.247813411931925, "VOTRIENT": 1.0027131880958766, "YERVOY": 6.7155303973396485, "null": 1.8330048948881976}
\ No newline at end of file
+{"IBUPROFEN": 86.64669945403669, "null": 0.7587588607454253}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6294.json
index 7dbcdc8de4f..e835822ccf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6294.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6294.json
@@ -1 +1 @@
-{"ARANESP": 9.572433499343148, "CICLOSPORIN": 2.959632448715252, "PEGASYS": 3.8031219938512897, "PEGINTRON": 11.375328909316169, "SOLIRIS": 7.502961139070839, "null": 1.9728299919157053}
\ No newline at end of file
+{"ADEMPAS": 21.72114957276768, "ALEMTUZUMAB": 5.660486288631719, "APIXABAN": 2.503542633395959, "FENTANYL": 1.7553140460071446, "FIASP": 41.24580207192502, "FILGRASTIM": 13.037577282455592, "HIZENTRA": 219.78482144089944, "HUMALOG": 1.293946590310646, "HUMAN": 15.549653054716249, "HYQVIA": 213.1398935689801, "IBUPROFEN": 11.321036271383736, "KYPROLIS": 21.52517691668857, "LEVOFLOXACIN": 5.241616493192903, "LYUMJEV": 378.7068424793442, "MIDAZOLAM": 7.584058825131398, "OPSUMIT": 8.780897268907744, "PRIVIGEN": 7.781073874128937, "TRACLEER": 6.628843076772189, "null": 1.591155509045805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6295.json
index c436ea2e1e4..0ed780c5c8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6295.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6295.json
@@ -1 +1 @@
-{"COSENTYX": 6.5848138188840855}
\ No newline at end of file
+{"ALEMTUZUMAB": 18.689215699090266, "BONVIVA": 24.87970433586598, "DARZALEX": 12.423451496536437, "ENTYVIO": 4.642307028150763, "FENTANYL": 2.88855702159754, "HIZENTRA": 15.36360875389692, "ILARIS": 144.8934447434867, "KEYTRUDA": 2.272715349646189, "KYPROLIS": 133.22205638618416, "NAGLAZYME": 25.48472702528333, "PRIVIGEN": 13.5764120125042, "REMDESIVIR": 58.46320675984806, "SITAGLIPTIN": 175.88972800076286, "YONDELIS": 170.21029631779604, "null": 2.782901928947761}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6296.json
index fa66ab33a30..5915f0ea99a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6296.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6296.json
@@ -1 +1 @@
-{"null": 3.0632229490426384}
\ No newline at end of file
+{"null": 4.686479064305307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6297.json
index dbfefb0c7ce..211ef9ee626 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6297.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6297.json
@@ -1 +1 @@
-{"null": 1.3278020383506333}
\ No newline at end of file
+{"null": 1.1813139140775986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6298.json
index 056d00ae5e1..1e1bfe6c9e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6298.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6298.json
@@ -1 +1 @@
-{"COMIRNATY": 3.606310516070311, "SPIKEVAX": 1.0777356406993024, "TOZINAMERAN": 9.715910758572596}
\ No newline at end of file
+{"ELIQUIS": 11.547970325496902, "HIZENTRA": 113.78499873608274, "HUMAN": 68.80740742910157, "LYUMJEV": 262.73610743808274, "OPSUMIT": 12.164491741736969, "null": 0.7414321923633586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6299.json
index ba39dd568dc..0f607d251bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6299.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6299.json
@@ -1 +1 @@
-{"AUBAGIO": 8.346193704912755, "BOSULIF": 11.528472180872493, "CLOPIDOGREL": 1.8862380833283103, "DEXAMETHASONE": 2.7458977960224944, "ELIQUIS": 1.029396424543198, "FAMPYRA": 8.648097353368252, "GARDASIL": 1.2338174237761756, "HUMALOG": 1.572693094680262, "KEPPRA": 1.4239388973220473, "LYRICA": 3.0366675408993498, "OCRELIZUMAB": 51.69733706757736, "OPTIMARK": 3.9354419225954103, "PEGASYS": 2.3608292066645986, "PEGINTRON": 4.7922438923996005, "TOZINAMERAN": 1.3439210651302145, "ZOSTAVAX": 2.9671968753821045, "null": 1.0315308787240127}
\ No newline at end of file
+{"LYUMJEV": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/63.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/63.json
index 50694133ff6..0b3df841114 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/63.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/63.json
@@ -1 +1 @@
-{"null": 1.8059144093544437}
\ No newline at end of file
+{"COMIRNATY": 2.8015424085311595, "SPIKEVAX": 0.8290477541783507, "TOZINAMERAN": 1.0841694060718703, "VAXZEVRIA": 0.32485038601992, "XARELTO": 61.50583073755554, "null": 0.635333706161139}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/630.json
index 64158ed4c9b..5610562ceb0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/630.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/630.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 16.781670821873718, "EVRA": 74.67275309781097, "KENTERA": 130.10739102167346, "null": 13.550628420921498}
\ No newline at end of file
+{"COMIRNATY": 0.5974570785564416, "ELIQUIS": 8.135015066755319, "FORXIGA": 11.830240313058722, "null": 1.0261683472874774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6300.json
index c8ba9eef98a..3567e569364 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6300.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6300.json
@@ -1 +1 @@
-{"ABILIFY": 4.397965829307505, "ARIPIPRAZOLE": 24.16745361524234, "BIKTARVY": 6.87463343559486, "BRINTELLIX": 3.43739688411783, "BUPRENORPHINE": 4.591784747475368, "CHAMPIX": 4.484071041794281, "DULOXETINE": 10.919322025908905, "ENTACAPONE": 28.811704935331065, "FYCOMPA": 17.46253025377572, "KEPPRA": 2.989333532519069, "LATUDA": 11.349998166176958, "LEVETIRACETAM": 2.4905237008043377, "LURASIDONE": 86.42905429623825, "LYRICA": 3.333550984218779, "OLANZAPINE": 19.83305203951076, "PANTOPRAZOLE": 12.139531286875318, "VFEND": 4.118966244746465, "ZYPREXA": 8.148108422900913, "null": 1.9401744227569584}
\ No newline at end of file
+{"null": 1.1414720922686423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6301.json
index 658982edb01..5ac1af2305d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6301.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6301.json
@@ -1 +1 @@
-{"KEPPRA": 19.181150619546123, "null": 1.7209970373810626}
\ No newline at end of file
+{"HIZENTRA": 163.47307428434308, "IBUPROFEN": 68.27301634097113, "LYUMJEV": 1638.7925262499334, "null": 0.935552240850714}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6302.json
index d348bff2409..c590066f8d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6302.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6302.json
@@ -1 +1 @@
-{"null": 1.7813829783242132}
\ No newline at end of file
+{"ADEMPAS": 120.68576651036204, "HIZENTRA": 116.2209149337925, "HUMALOG": 6.380572445495285, "OPSUMIT": 40.250713934014506, "null": 1.0560246090607563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6303.json
index c84f8674583..45caab43ea7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6303.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6303.json
@@ -1 +1 @@
-{"ABILIFY": 11.225204172208752, "BUPRENORPHINE": 13.716209978852586, "COMTAN": 78.08807940996124, "CYMBALTA": 3.636535455816395, "null": 1.3909240487399306}
\ No newline at end of file
+{"FIASP": 117.93992238579548, "HIZENTRA": 68.70267233407614, "LYUMJEV": 835.8845780395651, "null": 2.7002148649286277}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6304.json
index 6ddd67c5ff4..40baaca5f18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6304.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6304.json
@@ -1 +1 @@
-{"null": 3.9844657603791687}
\ No newline at end of file
+{"CRESEMBA": 535.8320072993289, "HIZENTRA": 108.68076930071598, "IBUPROFEN": 28.950730584148705, "OPSUMIT": 29.90218666238063, "null": 0.7339776334505721}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6305.json
index 64447fb8e5a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6305.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6305.json
@@ -1 +1 @@
-{"null": 2.8246314187502346}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6306.json
index f004538aee5..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6306.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6306.json
@@ -1 +1 @@
-{"LURASIDONE": 4464.526009175805, "null": 1.0692653319242271}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6307.json
index 0f3bcd3e807..59a033543eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6307.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6307.json
@@ -1 +1 @@
-{"null": 4.680092339331298}
\ No newline at end of file
+{"BUPIVACAINE": 273.91631586866765, "FENTANYL": 23.9480347347853, "HIZENTRA": 170.48858648857654, "null": 0.7182695033999078}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6308.json
index 7365040232c..f2180f62d12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6308.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6308.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3387539205734882, "COVID19": 5.760710746971374, "TOZINAMERAN": 4.617190615780875}
\ No newline at end of file
+{"COMIRNATY": 1.9411218735790416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6309.json
index 30f1cb671c4..32600fbe3e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6309.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6309.json
@@ -1 +1 @@
-{"ABILIFY": 12.03718113707504, "BUPRENORPHINE": 48.42419137200845, "FENTANYL": 12.149594455958894, "NUCALA": 38.69229326411551, "SUBOXONE": 8.724636866096482, "null": 3.4167243693843647}
\ No newline at end of file
+{"null": 2.468161136512688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/631.json
index 0c0aae2be42..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/631.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/631.json
@@ -1 +1 @@
-{"ALDARA": 90.73690072666808, "AMELUZ": 97.91933944061462, "COMIRNATY": 1.01827621162724, "COVID19": 5.012030946021421, "EVRA": 38.631953824218456, "KENTERA": 68.09048612112686, "QUTENZA": 16.39090043961273, "SPIKEVAX": 2.279170478242345, "ZYCLARA": 39.556561252101694, "null": 1.120720499586796}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6310.json
index b696bb68cb7..90cfdac823c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6310.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6310.json
@@ -1 +1 @@
-{"ABILIFY": 36.76274515306304, "ARIPIPRAZOLE": 5.008573926948478, "BRINTELLIX": 1.3613874163786892, "CHAMPIX": 20.01295082233087, "CYMBALTA": 2.131327960116097, "FYCOMPA": 13.786134240113562, "GARDASIL": 2.1388317055107806, "INFANRIX": 8.903119479406502, "KAFTRIO": 4.700152995709196, "KEPPRA": 9.360923562311852, "LATUDA": 2.784330587886993, "LEVETIRACETAM": 4.953128146583439, "MMRVAXPRO": 1.2625274038379313, "PEGASYS": 1.1448967503462324, "RIBAVIRIN": 2.737295244151301, "SIFROL": 11.775302922678398, "TAMIFLU": 2.408148543568479, "ZYPREXA": 1.2436394825325965, "null": 2.236225875340597}
\ No newline at end of file
+{"HIZENTRA": 991.936128420792, "null": 0.3137065143448349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6311.json
index 84726a27b10..037c613c790 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6311.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6311.json
@@ -1 +1 @@
-{"ABILIFY": 127.7461421799497, "BELIMUMAB": 3441.48211353264}
\ No newline at end of file
+{"HIZENTRA": 49.467740061401805, "null": 3.109713198277843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6312.json
index b442fd4de2e..16fe6ee13d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6312.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6312.json
@@ -1 +1 @@
-{"ABILIFY": 8.349169416418253, "AIMOVIG": 21.65268290935972, "ALISKIREN": 173.58498184190398, "CHAMPIX": 7.266990683499798, "ESOMEPRAZOLE": 16.45643956581091, "IVABRADINE": 98.99076893959575, "KALETRA": 6.244526468310814, "KEPPRA": 6.4103180099559705, "LEVETIRACETAM": 5.675585405055448, "OLANZAPINE": 3.244798425416371, "PEGASYS": 1.5496441163953698, "ZYPREXA": 3.182268678831566, "null": 2.142239847496612}
\ No newline at end of file
+{"ADEMPAS": 51.3638777441586, "ALEMTUZUMAB": 5.814330638778379, "COMIRNATY": 0.0504987332688643, "ELIQUIS": 0.9113301231394668, "ENTYVIO": 3.284082859066214, "FIASP": 120.90463252864572, "HIZENTRA": 117.67972067746966, "HUMALOG": 1.8711707784701157, "HUMAN": 13.453912482055925, "HYQVIA": 200.33254763251284, "IBUPROFEN": 8.791612452961692, "KYPROLIS": 35.94145743829901, "LYUMJEV": 1479.5861239778103, "OPSUMIT": 17.137490491910704, "TRACLEER": 5.363027835015031, "VAXZEVRIA": 0.0762891607106578, "null": 1.5775231691529854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6313.json
index 94354e3ad26..5a45fa881a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6313.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6313.json
@@ -1 +1 @@
-{"null": 4.772904135896998}
\ No newline at end of file
+{"HIZENTRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6314.json
index bb2d406b6f9..3b0ed86c868 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6314.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6314.json
@@ -1 +1 @@
-{"CIMZIA": 5.7391930925206855, "STELARA": 12.02394070185708, "null": 1.4917819978264557}
\ No newline at end of file
+{"null": 1.7801097803014172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6315.json
index bd8dcff0fcc..37416e191b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6315.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6315.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 1.3277615966690812, "ALIMTA": 1.2217676513332063, "BETMIGA": 2.477451035451456, "BEXSERO": 4.397909738079209, "BRIDION": 1.305043436998812, "BRILIQUE": 6.176442973481381, "BRUKINSA": 8.51423323903242, "CLOPIDOGREL": 3.818921652573308, "COMIRNATY": 1.281429678673442, "COVID19": 1.5356193917513834, "CYTARABINE": 1.006796390255595, "ELIQUIS": 2.1587102200507315, "ENOXAPARIN": 4.77187554756768, "EXJADE": 1.3381529821441656, "GARDASIL": 1.3005935288454615, "HUMAN": 1.4407784324805752, "INFANRIX": 4.410442287899118, "INTEGRILIN": 5.555594037234224, "LEMTRADA": 6.096998294941883, "LIXIANA": 3.082395822676621, "MENVEO": 3.684071865941208, "MMRVAXPRO": 5.56932217385685, "NIMENRIX": 3.654132230849064, "NOVONORM": 2.9587553744478896, "NPLATE": 13.91609803673088, "PANTOPRAZOLE": 2.1824334867224597, "PEMBROLIZUMAB": 1.0668260565585503, "PLAVIX": 2.707744136286437, "PREVENAR": 10.01083318556207, "ROTATEQ": 2.2613576401587507, "SUTENT": 1.0445023685695831, "SYNAGIS": 1.67305795506847, "TAMIFLU": 1.8873022333981933, "TEMODAL": 4.8169906168205685, "TEMOZOLOMIDE": 3.127501591806748, "TWINRIX": 2.077163099721941, "VAXZEVRIA": 3.155442149391035, "XARELTO": 1.5932245883826373, "null": 1.0081274344732911}
\ No newline at end of file
+{"LEVOFLOXACIN": 15.258111856376894, "null": 6.6879166907085725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6316.json
index c935f7d4e55..4c4d2be193a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6316.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6316.json
@@ -1 +1 @@
-{"ATAZANAVIR": 4.978780549385239, "BOTULINUM": 5.881226829385805, "BRIVARACETAM": 23.244622915869808, "BRIVIACT": 26.51918637846004, "CANNABIDIOL": 11.787846729550232, "CELSENTRI": 38.55345919083141, "CHAMPIX": 2.298467437469513, "DESLORATADINE": 18.491660505131037, "FYCOMPA": 9.475416310747857, "GARDASIL": 2.7736409903945827, "KEPPRA": 33.76281055809101, "LACOSAMIDE": 23.317908781810512, "LEVETIRACETAM": 22.29898042537243, "MMRVAXPRO": 1.8729285324702656, "OLANZAPINE": 1.8090657434774715, "VIMPAT": 26.92714130644329, "ZYPREXA": 1.7165260925780097, "null": 2.104007524086255}
\ No newline at end of file
+{"ADEMPAS": 52.15594348002582, "FIASP": 48.42270193240421, "HIZENTRA": 261.0206380197223, "HUMAN": 24.76123191038789, "HYQVIA": 105.55391116455054, "IBUPROFEN": 8.285468295992716, "LEVOFLOXACIN": 6.847748714381694, "LYUMJEV": 468.8194607652781, "OPSUMIT": 9.687021743806795, "null": 1.3044721210020522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6317.json
index 24c44e8e7ad..5c6f5d8d53e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6317.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6317.json
@@ -1 +1 @@
-{"VIAGRA": 62.175907366819686, "null": 2.427217477504736}
\ No newline at end of file
+{"HIZENTRA": 137.7835572330428, "null": 1.6029054922303072}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6318.json
index 3d88e0212c1..187ced3586d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6318.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6318.json
@@ -1 +1 @@
-{"SUTENT": 2.6045755469495013, "null": 2.159711925015488}
\ No newline at end of file
+{"ABATACEPT": 142.59488943461523, "ADALIMUMAB": 7.183673498558482, "ADEMPAS": 31.05025116633616, "CAELYX": 16.34110469836217, "ENBREL": 3.996412962877269, "HIZENTRA": 41.14545870528124, "null": 0.6659534483549496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6319.json
index dee41cbb58b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6319.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6319.json
@@ -1 +1 @@
-{"null": 1.5645262835561466}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/632.json
index 041901e54a3..518471a3aca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/632.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/632.json
@@ -1 +1 @@
-{"ALDARA": 637.9441892819284, "AMELUZ": 4173.279286329315, "IMIQUIMOD": 497.746941445022, "ZYCLARA": 461.3967579998862, "null": 2.8748535685179606}
\ No newline at end of file
+{"ABILIFY": 4.135706842858733, "AERIUS": 1.828398074702796, "AIMOVIG": 0.5214476328984432, "ATRIPLA": 0.1821075492031999, "BRINTELLIX": 4.140379681509965, "BRIVARACETAM": 8.412027317854058, "BRIVIACT": 14.593799580341882, "BUPRENORPHINE": 0.4885890476762373, "BYDUREON": 0.7081728167570273, "CHAMPIX": 24.215432472450004, "CIMZIA": 0.2404152624969502, "CLOPIDOGREL": 0.345818314023289, "COMIRNATY": 0.0859527958056542, "COSENTYX": 0.8139709265258034, "CYMBALTA": 8.667833588769883, "DULOXETINE": 1.961393437215044, "EXFORGE": 1.308833231272926, "FENTANYL": 0.7749470217053649, "FYCOMPA": 25.77277814290632, "GARDASIL": 0.4988184990508889, "HARVONI": 2.0121463620690245, "HUMALOG": 0.4740807180210366, "IBRANCE": 0.2554818270859677, "IBUPROFEN": 0.7782290412227585, "INCIVO": 1.1013214453710425, "INTUNIV": 65.12814380348618, "KAFTRIO": 7.847213999531769, "KEPPRA": 11.922926947431003, "KEYTRUDA": 0.2417846175610502, "LANTUS": 0.1818850660578749, "LATUDA": 13.500701450748942, "LEVETIRACETAM": 5.159217232548572, "LYRICA": 2.882818904409927, "MIDAZOLAM": 1.302249647027483, "MMRVAXPRO": 0.4632709761308974, "OLANZAPINE": 1.2889885653283486, "OPTIMARK": 0.4826981367891444, "PEGASYS": 4.828531391228215, "PEGINTERFERON": 0.6999116182196764, "PEGINTRON": 3.96912224177088, "PERAMPANEL": 33.01116502743489, "PLAVIX": 0.1878124576687991, "PLEGRIDY": 1.3150329789721982, "PREGABALIN": 3.960693525807887, "RIBAVIRIN": 1.3132255400685613, "SPIKEVAX": 0.0969362199677006, "SUBOXONE": 2.00119379478964, "SUTENT": 0.2107909486100078, "TAMIFLU": 0.8149774732839162, "TESTOSTERONE": 5.383876922768514, "TOZINAMERAN": 0.3180551906832697, "TRUVADA": 0.1071776135659528, "VARENICLINE": 9.479165282595376, "VAXZEVRIA": 0.0828727273763523, "VIMPAT": 3.642161823997201, "XELJANZ": 0.237303799188501, "XOLAIR": 0.4526025473535386, "XTANDI": 0.3661994611420662, "XYREM": 2.2570229130518658, "ZYPREXA": 2.424903205000438, "null": 2.369138050245866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6320.json
index 69efa8ccda6..648cc02d18f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6320.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6320.json
@@ -1 +1 @@
-{"CICLOSPORIN": 35.59377919423019}
\ No newline at end of file
+{"HIZENTRA": 505.8812969775844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6321.json
index 17a0e9bdf6b..a3f574bd452 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6321.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6321.json
@@ -1 +1 @@
-{"OLANZAPINE": 205.8791551113204}
\ No newline at end of file
+{"ADEMPAS": 34.219016949031506, "ELIQUIS": 1.0827819579804312, "FILGRASTIM": 18.66190562131812, "HIZENTRA": 265.6991137539359, "HYQVIA": 191.81846317545907, "IBUPROFEN": 15.67994701180688, "LYUMJEV": 121.98537586232004, "NAGLAZYME": 29.761105911720964, "OPSUMIT": 13.127551964363512, "PRIVIGEN": 8.978221153586317, "null": 1.688192179677232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6322.json
index c57232a4ba2..94816b5b20f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6322.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6322.json
@@ -1 +1 @@
-{"null": 1.0073536249268118}
\ No newline at end of file
+{"AZATHIOPRINE": 247.60140598811068, "null": 1.606593286726563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6323.json
index 383eae86ca2..3fa48b3e8f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6323.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6323.json
@@ -1 +1 @@
-{"null": 4.02283837449332}
\ No newline at end of file
+{"HIZENTRA": 396.8216973003799, "null": 0.9994281994518696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6324.json
index f268a7e81a7..ec21d1b022f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6324.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6324.json
@@ -1 +1 @@
-{"COVID19": 1.5460431666419967, "CYMBALTA": 7.860610807629707}
\ No newline at end of file
+{"HIZENTRA": 296.2544242157266, "null": 1.783984778831243}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6325.json
index c79672b45ae..ecd1a1b94f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6325.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6325.json
@@ -1 +1 @@
-{"null": 10.510138366415156}
\ No newline at end of file
+{"HIZENTRA": 126.2527781221119, "null": 1.306346535786408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6326.json
index d9c1927a6c0..db15c508839 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6326.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6326.json
@@ -1 +1 @@
-{"null": 1.0450165374005}
\ No newline at end of file
+{"HIZENTRA": 263.1970730381342, "OPSUMIT": 21.852188937375036, "null": 1.2516925285640812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6327.json
index 77f341d6aad..1109300759e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6327.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6327.json
@@ -1 +1 @@
-{"AERIUS": 25.24293533690124, "CLOPIDOGREL": 2.3326561609602443, "IBRANCE": 3.822846010394968, "LANTUS": 1.4493480272321544, "PEGASYS": 2.8197355795100525, "RELVAR": 17.448855258315934, "TOZINAMERAN": 1.1556889227221083, "XELJANZ": 3.304762953454073, "XOLAIR": 4.549457264915034, "null": 1.7716497497849286}
\ No newline at end of file
+{"AFINITOR": 17.269352634420148, "CRIXIVAN": 46.29286137177991, "CYMBALTA": 4.58275815057203, "EVEROLIMUS": 55.71051236674529, "IRESSA": 21.533846927067938, "SIMPONI": 4.872223826258463, "SUTENT": 3.7793926545348615, "null": 0.8483160152276764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6328.json
index 9dc62f0ad30..ea9ddb5028f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6328.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6328.json
@@ -1 +1 @@
-{"null": 1.5056734221207937}
\ No newline at end of file
+{"BIKTARVY": 73.6878714520271, "null": 0.3511171371258133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6329.json
index 4ab8c7f1f34..0210f9f8173 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6329.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6329.json
@@ -1 +1 @@
-{"BUDESONIDE": 1.7856989043994866, "DEXAMETHASONE": 1.8908072867145604, "GARDASIL": 2.415028433920557, "KEPPRA": 1.3784597316534477, "MMRVAXPRO": 19.45851738799934, "NIMENRIX": 7.893943250534347, "NUCALA": 4.993417676228683, "ROTATEQ": 13.229747586236387, "null": 2.1324966264655565}
\ No newline at end of file
+{"ASPARAGINASE": 11.00472420069494, "BELANTAMAB": 398.911522618452, "BYETTA": 3.1636220843315157, "COMBIVIR": 5.414505842323663, "COMIRNATY": 0.0598643990748922, "COSENTYX": 1.1206454315658338, "CYMBALTA": 1.2530940053032866, "ELIQUIS": 2.6239394454792184, "FORSTEO": 8.07887824496958, "JANUMET": 8.933167948448475, "JANUVIA": 5.109310757510031, "KEPPRA": 0.9024869334203174, "NAGLAZYME": 19.263277958292253, "PEGASYS": 0.5213149379948985, "SIMPONI": 1.9389906678960755, "SPIKEVAX": 0.0677165115821884, "STELARA": 0.9993210219863178, "SUTENT": 2.2975392509032786, "SYNAGIS": 12.191743656025077, "TRACTOCILE": 71.60826009645038, "VAXZEVRIA": 0.0755287578476281, "XELJANZ": 1.0086637962257488, "ZOSTAVAX": 2.3827748241481728, "null": 1.7128672571929424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/633.json
index bbe7ba03d0e..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/633.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/633.json
@@ -1 +1 @@
-{"null": 13.602521812653652}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6330.json
index f48d1ad0455..646f18a2534 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6330.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6330.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 36.49302472931458, "null": 2.1589937134569936}
\ No newline at end of file
+{"ACLIDINIUM": 924.4685547655546, "null": 0.6785948420994828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6331.json
index e69c2b220b8..9762c854030 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6331.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6331.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 5.428654464416129, "ELIQUIS": 13.014032694093794, "PEGASYS": 1.928213345591658, "PLAVIX": 4.91471827264757, "SUTENT": 1.4796877489251845, "null": 1.1694770797238778}
\ No newline at end of file
+{"null": 0.3476500171942541}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6332.json
index 8205089862a..05317853bca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6332.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6332.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7422415357580123, "FENTANYL": 10.43780825965789, "TOZINAMERAN": 3.50560238317168, "null": 1.3196238708651016}
\ No newline at end of file
+{"null": 18.997581423780414}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6333.json
index c7d2fc95bb4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6333.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6333.json
@@ -1 +1 @@
-{"AVAMYS": 8.52371067975638, "BENLYSTA": 15.603543282020508, "SUTENT": 2.286738651842473, "TOZINAMERAN": 1.0964640041783005, "null": 1.0514473464605192}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6334.json
index dab8393a56d..e6778d91726 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6334.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6334.json
@@ -1 +1 @@
-{"null": 4.809482967964405}
\ No newline at end of file
+{"MELPHALAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6335.json
index 885cd7e549a..5381fb332e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6335.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6335.json
@@ -1 +1 @@
-{"null": 1.3429555258382595}
\ No newline at end of file
+{"ADVATE": 3940.9703485076943, "KOGENATE": 5583.317080444805, "null": 0.40485381406118}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6336.json
index 075de6704ea..5e06dc16078 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6336.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6336.json
@@ -1 +1 @@
-{"TOZINAMERAN": 3.329602349681321}
\ No newline at end of file
+{"ADVATE": 1497.021142300464, "null": 0.7127343957588432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6337.json
index 16ca5800760..4fef4ee7d0a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6337.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6337.json
@@ -1 +1 @@
-{"ADCIRCA": 5.8371633722833005, "APIDRA": 1.3526228470646458, "BRIDION": 6.427581111025683, "CHAMPIX": 1.1739934383973578, "ENBREL": 6.027486491469131, "EXFORGE": 1.4832821794798228, "GARDASIL": 1.140609786095211, "LEVOFLOXACIN": 1.1415264905008795, "MICARDIS": 5.952274516129602, "OMALIZUMAB": 1.0857343389625034, "RASILEZ": 4.069912583406109, "XOLAIR": 2.791571589983282, "null": 3.9569876829917208}
\ No newline at end of file
+{"ANAKINRA": 10.400095301422152, "BUDESONIDE": 3.43575326457935, "COMIRNATY": 0.0954007366563014, "KEPPRA": 3.3926071680634684, "SODIUM": 199.73286981245587, "TIVICAY": 40.90244930920812, "null": 2.2571414995630104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6338.json
index 28b9df4cbcb..3e576441bc7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6338.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6338.json
@@ -1 +1 @@
-{"null": 2.1497644818720323}
\ No newline at end of file
+{"AIMOVIG": 2.2403828378560773, "ARIPIPRAZOLE": 1.399305265667914, "AUBAGIO": 1.1208199799021863, "AVAMYS": 1.7431401232654138, "BIKTARVY": 6.7353978046103, "BRINTELLIX": 7.180102541672565, "CHAMPIX": 1.7773419614214914, "CIRCADIN": 12.786826748189362, "COMIRNATY": 1.3798149750774935, "CYMBALTA": 1.3022073300137726, "ELIQUIS": 0.3001594832973379, "FAMPYRA": 2.771362875473496, "FORSTEO": 1.724110145367279, "GARDASIL": 2.699538546551396, "IBRANCE": 0.7409579344442543, "KAFTRIO": 21.767582149994027, "KEPPRA": 1.7512803107206243, "LATUDA": 2.301809176501264, "MELATONIN": 10.810926250453456, "MMRVAXPRO": 0.9861858893877692, "OLANZAPINE": 1.7952374518251757, "PEGASYS": 0.6177233343071902, "SPIKEVAX": 0.6929557482913573, "TOZINAMERAN": 0.3179073785917043, "VAXZEVRIA": 0.487523022846523, "VORICONAZOLE": 5.681869399632131, "XELJANZ": 0.5653058748899547, "XTANDI": 1.892253192391348, "XYREM": 12.422226735229687, "ZYPREXA": 1.2685238431321937, "null": 1.3856319375587316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6339.json
index dbedff01b90..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6339.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6339.json
@@ -1 +1 @@
-{"COMIRNATY": 2.2457231029240674, "FENTANYL": 5.064529233621383, "OMALIZUMAB": 3.105734476934358, "TOZINAMERAN": 2.3500726213227163, "null": 1.7278084019637734}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/634.json
index c1765ad31c9..62f5bc2a902 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/634.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/634.json
@@ -1 +1 @@
-{"ALDARA": 21.15855554628843, "AMELUZ": 252.3272667956982, "COMIRNATY": 2.016873632289655, "COVID19": 4.9708971392042685, "NEULASTA": 2.047586347678803, "QUTENZA": 30.260150448059377, "SPIKEVAX": 3.037670080509844}
\ No newline at end of file
+{"ABACAVIR": 0.1386567791964577, "ABILIFY": 0.1815959524678695, "ACTOS": 1.175484112281726, "ADCIRCA": 5.8131658178941805, "AFINITOR": 0.2487413405948704, "AIMOVIG": 0.937534736598728, "ALIMTA": 0.2828277948890248, "ALISKIREN": 20.724897050834283, "ANORO": 0.7861890983242991, "APIDRA": 0.3812248528604138, "APIXABAN": 0.1951244040258553, "APROVEL": 1.689888516389504, "ARANESP": 0.585744660134715, "ARAVA": 0.0190286434201432, "AVANDAMET": 12.503593489808305, "AVANDIA": 10.07954079592127, "AVASTIN": 0.541870266282464, "BEDAQUILINE": 0.7327884250187023, "BENLYSTA": 0.4941187740365932, "BETAFERON": 1.1973600793264272, "BETMIGA": 0.8929610216685305, "BEVACIZUMAB": 0.4365181703528745, "BIKTARVY": 0.6017202588597774, "BOSULIF": 0.9894814537201564, "BRILIQUE": 5.593026399990932, "BYDUREON": 0.4097488237450761, "BYETTA": 0.6811728611300676, "CAPECITABINE": 1.48520856334251, "CELLCEPT": 0.3113252151192647, "CHAMPIX": 2.283953208187737, "CICLOSPORIN": 0.1484985487215187, "CIMZIA": 0.2532933261882747, "CLOPIDOGREL": 3.490432957471067, "COAPROVEL": 1.0944861423766532, "COMBIVIR": 1.2563308239538375, "COMIRNATY": 1.7322701337276902, "COMPRESSION": 47.49339020417307, "COSENTYX": 0.5688810835398519, "CRIXIVAN": 1.327346192186044, "CYMBALTA": 0.3004043363948451, "CYTARABINE": 0.2491676499248327, "DEXAMETHASONE": 0.2904445955258929, "DULOXETINE": 2.379858591444589, "EFIENT": 7.759070931834747, "ELIQUIS": 0.7778489614185373, "ENBREL": 0.3543376115330638, "ENOXAPARIN": 0.86467882365087, "ENTRESTO": 1.7384238953779805, "EPADERM": 43.61989143589956, "EPIVIR": 1.0439428412680325, "ERLEADA": 0.999574206755215, "ESBRIET": 0.3521070481382887, "ESOMEPRAZOLE": 1.6234442849966662, "EVENITY": 5.096299573872878, "EVISTA": 0.7829392123548471, "EXFORGE": 2.862233653237765, "EYLEA": 0.5154368288947648, "FASENRA": 0.3416772509375727, "FEBUXOSTAT": 3.3446336817222884, "FORSTEO": 1.789678203092723, "FORXIGA": 0.6672819619555362, "GARDASIL": 0.3970097231448574, "GLIBENCLAMIDE": 2.21251521654856, "HUMALOG": 0.7898296355572638, "HUMIRA": 0.2327818300279601, "IBRANCE": 0.2026723571850956, "IBUPROFEN": 0.608959507767718, "ICLUSIG": 2.5644106512476155, "INCIVO": 0.4998969834026514, "INFLIXIMAB": 1.1922578834926945, "INSULIN": 4.271805844339797, "IRBESARTAN": 0.9160976127095628, "IVABRADINE": 25.267803954709017, "JAKAVI": 0.2705805199546156, "JANUMET": 0.5786498275579084, "JANUVIA": 0.4215252708196536, "JARDIANCE": 0.6788667374346921, "KEPPRA": 0.1557763815582921, "KEYTRUDA": 0.1006103073185521, "KYPROLIS": 2.0262142518999027, "LANTUS": 1.469011666416726, "LEVOFLOXACIN": 0.2715366650071039, "LYRICA": 0.4541391659473518, "MEPOLIZUMAB": 1.7387137105160118, "METHOTREXATE": 0.144186583742976, "MICARDIS": 2.07171917847922, "MIXTARD": 3.6450654210813416, "MODERNA": 0.3166057887742357, "MULTAQ": 1.3809324788890422, "NEXAVAR": 0.7217718635233089, "NILOTINIB": 4.542590492063399, "NOVOSEVEN": 1.3783734559680292, "NUCALA": 0.6580880509466841, "OFEV": 0.3333556552808072, "OLYSIO": 0.9174548369906912, "OMALIZUMAB": 0.3756719920040784, "OPSUMIT": 0.2740512527612732, "PANTOPRAZOLE": 0.4364535166369145, "PEGASYS": 0.5184705108603567, "PEGINTERFERON": 0.5113946502109898, "PEGINTRON": 0.6856057055346937, "PLAVIX": 4.222787338313758, "RANEXA": 8.825517861269901, "RANOLAZINE": 18.4296308397781, "RAPISCAN": 9.12085758322994, "RASILEZ": 2.3125374202489866, "RELVAR": 1.6465428690201194, "RIBAVIRIN": 0.4014099333775803, "RINVOQ": 0.7596771411411081, "RITUXIMAB": 0.2746110516690905, "RIVAROXABAN": 4.506459331394318, "ROACTEMRA": 0.4343457196928265, "SHINGRIX": 0.2110813474978278, "SILDENAFIL": 1.654420500526799, "SIMPONI": 0.5157576347508821, "SPIKEVAX": 1.0613695874303102, "SPRYCEL": 0.8778750148065424, "STALEVO": 1.1150691682388123, "STELARA": 0.5492178952647447, "STIVARGA": 0.3358899611670888, "SUBOXONE": 0.164055517762414, "SUTENT": 0.2430100557910285, "TAMIFLU": 0.4034471316343193, "TASIGNA": 6.415646484749315, "TESTOSTERONE": 2.889259044182473, "TICAGRELOR": 1.4384302679760557, "TIVICAY": 1.4903921997272145, "TOVIAZ": 0.6675474146013913, "TOZINAMERAN": 1.6341948041480927, "TRACLEER": 0.3175116516833114, "TRELEGY": 1.3004882427199842, "TRULICITY": 0.3689267467380046, "VAXZEVRIA": 0.4625339876381216, "VIAGRA": 2.8959427574340846, "VICTOZA": 0.3665535370498068, "VOTRIENT": 0.7238008530575838, "XELJANZ": 0.5384036323772633, "XELODA": 2.2384108583098943, "XOLAIR": 0.6513328961855684, "XTANDI": 0.2022695833341821, "ZOSTAVAX": 0.7136717334988326, "ZYLLT": 15.01791663778948, "ZYPREXA": 0.6335377991707976, "null": 0.9483752009342894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6340.json
index b8530e12de3..34d643ba9e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6340.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6340.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9458022611218733}
\ No newline at end of file
+{"COMIRNATY": 5.540192792947932, "GARDASIL": 2.321739191336306, "MENVEO": 9.48919609341109, "MMRVAXPRO": 2.752424731916186, "MODERNA": 2.4147188638591595, "NIMENRIX": 3.33883993661782, "SHINGRIX": 10.43495345706578, "SPIKEVAX": 4.637354806222072, "TOZINAMERAN": 0.4863432747318986, "TWINRIX": 4.11674735948964, "VAXZEVRIA": 1.7311906860528832, "ZOSTAVAX": 0.6712465962090826, "null": 0.0717308756661086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6341.json
index d0201796729..9c7145bdf09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6341.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6341.json
@@ -1 +1 @@
-{"AERIUS": 1.4549667507065962, "BYDUREON": 1.5401693914892267, "CHAMPIX": 2.0559874966711877, "COMIRNATY": 1.0711659787232233, "COSENTYX": 1.327849795222386, "ENTRESTO": 1.5834914956447323, "FASENRA": 1.8795875525728225, "HIZENTRA": 2.3012153729172047, "LATUDA": 1.8859694744591613, "LEFLUNOMIDE": 2.4240670151370165, "MENVEO": 2.147651021907916, "NEULASTA": 1.8862111285426904, "OMALIZUMAB": 1.351339832493733, "PRIVIGEN": 1.8367062859168504, "RASILEZ": 1.5286652363379034, "REVATIO": 1.1591738031855272, "RUCONEST": 134.7075176265005, "SUBOXONE": 4.073912171359331, "TAMIFLU": 1.3814128797660228, "TOVIAZ": 2.2650142803064, "TOZINAMERAN": 2.501904512951657, "TRELEGY": 1.5005753674442557, "XOLAIR": 5.751740422515013, "null": 1.7916746654100748}
\ No newline at end of file
+{"SPIKEVAX": 0.893119075811885, "SUBSTANCE": 13466.474301417627, "VAXZEVRIA": 3.230476365017457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6342.json
index 6441278cb72..be96e12061e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6342.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6342.json
@@ -1 +1 @@
-{"PEGASYS": 5.874985072507446, "PLAVIX": 5.654245672630367, "RITUXIMAB": 12.82537123462368, "SUTENT": 3.232718349059031, "TOZINAMERAN": 1.850590914239552}
\ No newline at end of file
+{"BYDUREON": 5.139732699352935, "COMIRNATY": 0.4205473351110214, "KESIMPTA": 41.89252635681664, "METHOTREXATE": 2.800353488995893, "SIMPONI": 2.1418492635082096, "SPIKEVAX": 0.6780013743187486, "STELARA": 2.3989453311664657, "TOZINAMERAN": 0.9785244056751036, "VAXZEVRIA": 12.387963556737883, "ZYPADHERA": 30.009545814606085, "null": 0.1442306087811027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6343.json
index 10c80ca10a3..d8bcc3a7f77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6343.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6343.json
@@ -1 +1 @@
-{"ACETYLSALICYLIC": 102.16034905003669, "ARAVA": 1.3340144848617752, "AVAMYS": 1.226767480138576, "BENLYSTA": 4.8021558954317936, "CASPOFUNGIN": 6.454624956109873, "CICLOSPORIN": 1.019083390197072, "CIMZIA": 1.37110829207194, "COMBIVIR": 2.109159832113177, "COSENTYX": 3.3515868093988828, "ENBREL": 3.401486304602118, "ENTYVIO": 2.016090287879069, "ETANERCEPT": 23.03344890703354, "EXJADE": 1.5222316641198428, "FASENRA": 7.445291485187445, "FULVESTRANT": 1.994306350683445, "GARDASIL": 3.817038147783936, "HALAVEN": 3.576763952068084, "HIZENTRA": 1.5760521188708994, "IBUPROFEN": 1.405917120921132, "INCIVO": 1.4123739793598131, "MENVEO": 4.874829537603974, "MEPOLIZUMAB": 1.2738733663426218, "METHOTREXATE": 2.2388331904949275, "MICARDIS": 1.8008913652518554, "MMRVAXPRO": 8.14258624957039, "NAGLAZYME": 4.014109436519468, "NIMENRIX": 1.900354630339139, "NUCALA": 3.3772614685498428, "OMALIZUMAB": 1.6076169970379297, "PREVENAR": 4.413218079527683, "PRIVIGEN": 1.5464044869399505, "RINVOQ": 1.148730060223374, "RITUXIMAB": 1.0898595563192872, "ROACTEMRA": 1.995190968162498, "SIMPONI": 13.136003645350218, "SOLIRIS": 1.5269345049446734, "STELARA": 2.339977142940845, "SYNFLORIX": 41.241806972258544, "TRELEGY": 1.033459956660282, "XELJANZ": 1.922683794171209, "XOLAIR": 2.452025554320373, "ZOSTAVAX": 1.5341483049881337, "ZYPREXA": 1.0618785684890562, "null": 1.2727583604182164}
\ No newline at end of file
+{"ACTRAPID": 19.445792850003738, "APIDRA": 5.369383929404512, "BETAFERON": 192.44242192436116, "BUVIDAL": 90.3706894690186, "BYDUREON": 15.622032956712207, "COMIRNATY": 0.0888318327569943, "FASLODEX": 5.592909031300689, "INSULIN": 4.344750862787473, "LANTUS": 1.394201665197358, "MIXTARD": 68.76364098067428, "PEGASYS": 0.7709716078715333, "PEGINTRON": 9.707400605901418, "SPIKEVAX": 0.1492077957144707, "SUBOXONE": 4.117068561323337, "VAXZEVRIA": 0.1477954829863507, "ZYPADHERA": 105.09789913813586, "null": 1.873839583717585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6344.json
index 2135036b268..ae0987c2b9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6344.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6344.json
@@ -1 +1 @@
-{"BENLYSTA": 6.261594681430518, "BUDESONIDE": 8.703536075529568, "CIMZIA": 5.9039332459305065, "COSENTYX": 6.251497993451569, "ENBREL": 2.7230239674428502, "ENTYVIO": 4.280214924962643, "GARDASIL": 5.188792845996884, "HIZENTRA": 7.556099067877654, "HUMALOG": 1.5469946723010035, "METHOTREXATE": 3.105040603046501, "PEGASYS": 1.3454661535180847, "STELARA": 2.592391030267944, "XELJANZ": 8.588485839355084, "XOLAIR": 2.425971990554596, "null": 1.2871615419338065}
\ No newline at end of file
+{"null": 1.6587268853734356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6345.json
index d8fef1f2e33..d379008a45f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6345.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6345.json
@@ -1 +1 @@
-{"null": 1.0844206131302538}
\ No newline at end of file
+{"null": 1.920349924069633}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6346.json
index dd7faddcad9..dcc1a9cb675 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6346.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6346.json
@@ -1 +1 @@
-{"SYNFLORIX": 1141.1071288927312, "null": 1.47872275687022}
\ No newline at end of file
+{"APIDRA": 10.28279977319746, "BETAFERON": 94.60407854944586, "COMIRNATY": 0.1119105222575642, "FIASP": 58.28044840631933, "HUMALOG": 5.540685252400602, "INSULIN": 59.340039074140186, "LANTUS": 7.505546131366235, "LEVEMIR": 93.29753353999894, "NOVORAPID": 68.00657879180505, "SOMATROPIN": 88.83987535467666, "null": 0.3607649745336309}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6347.json
index f89525acf89..d6b9ac8a057 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6347.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6347.json
@@ -1 +1 @@
-{"BOSULIF": 113.38880249549912, "BOSUTINIB": 350.1316962967879, "DASATINIB": 512.8557772777307, "ICLUSIG": 93.7088246239684, "IMATINIB": 162.23793971528576, "NILOTINIB": 196.87095117596877, "SPRYCEL": 192.5274851188784, "TASIGNA": 41.05154737863561}
\ No newline at end of file
+{"ABASAGLAR": 11.780928036942004, "ACLASTA": 13.30794375957594, "AIMOVIG": 4.126137639696816, "APIDRA": 6.970080801041829, "ARANESP": 1.3465769623170667, "ARAVA": 0.1682488060226157, "BENLYSTA": 4.221267432906119, "BETAFERON": 8.995978415991233, "BYDUREON": 11.968657832523132, "BYETTA": 3.464263353827132, "CICLOSPORIN": 0.7205150631259861, "CIMZIA": 2.538978821496924, "COMIRNATY": 0.1596374221125622, "COSENTYX": 5.115133675427511, "CYMBALTA": 0.7319534471546499, "DULOXETINE": 1.4595966336636128, "ELIQUIS": 0.3940101859859822, "ENBREL": 7.89755440015157, "ENOXAPARIN": 4.309826194967568, "ENTYVIO": 0.7923024515339918, "EVENITY": 3.1019959216213184, "EVISTA": 18.31569071064464, "FASLODEX": 4.191793420797693, "FIASP": 8.970280605012752, "FORSTEO": 17.679281144932983, "HIZENTRA": 2.142211683998021, "HUMALOG": 7.220145160667847, "HUMIRA": 2.6769840528941566, "INHIXA": 30.02566080062492, "INSULIN": 3.162224010419262, "LANTUS": 8.493984898905378, "LEVEMIR": 9.22856888643478, "LYUMJEV": 27.97931356491879, "METHOTREXATE": 0.8167021640885794, "NOVORAPID": 1.4023276383522192, "NUCALA": 1.0561764213381255, "OMALIZUMAB": 6.122515747877794, "OMNITROPE": 14.132800957583653, "PEGASYS": 3.0045083914284625, "PEGINTRON": 1.18004339706036, "PLAVIX": 0.8736387854160049, "PLEGRIDY": 25.98200335223188, "REBIF": 15.851783606178689, "ROACTEMRA": 1.562454514034264, "SAXENDA": 17.658288170524308, "SHINGRIX": 1.1686789182905104, "SIMPONI": 3.4467253054656912, "SOMATROPIN": 10.547298936069764, "SOMAVERT": 42.68564604487056, "SPIKEVAX": 0.2586590329341837, "STELARA": 0.3087805610200507, "TERROSA": 42.52910538142604, "TOUJEO": 9.702491641405846, "TREMFYA": 1.4934006242473583, "TRULICITY": 12.956717524805022, "VAXZEVRIA": 0.4189642471308973, "VICTOZA": 5.832131430485554, "XOLAIR": 1.4777847265480313, "null": 1.2476942447430577}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6348.json
index 40cebb92751..142a93fcc41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6348.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6348.json
@@ -1 +1 @@
-{"ICLUSIG": 2288.780376911525}
\ No newline at end of file
+{"BETAFERON": 88.50121750688037, "BYDUREON": 17.04512304845716, "FASLODEX": 11.167714170738469, "PEGASYS": 1.949805081057718, "PEGINTRON": 13.684776272772432, "SHINGRIX": 6.526266015407827, "SPIKEVAX": 0.5389346276588334, "VAXZEVRIA": 0.3918808099117049, "ZOSTAVAX": 9.622089204100291, "null": 1.313595402201658}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6349.json
index 8181675d23f..d9128a09dc5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6349.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6349.json
@@ -1 +1 @@
-{"ASPARAGINASE": 26.63528147586704, "FORXIGA": 81.24626573227967, "JARDIANCE": 259.70850349443134, "VIAGRA": 12.475380514967512}
\ No newline at end of file
+{"COMIRNATY": 0.973644222659326, "SPIKEVAX": 1.0611587387507342, "null": 1.1935669868911705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/635.json
index 4f165be8a5c..a81fa435e69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/635.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/635.json
@@ -1 +1 @@
-{"ALDARA": 1589.5166149094773, "null": 2.373810070128011}
\ No newline at end of file
+{"ADENURIC": 15.479043771721944, "AVANDAMET": 100.22710915779828, "AVANDIA": 77.83761588051956, "BRILIQUE": 10.928026299029318, "CHAMPIX": 1.1462188915967515, "CLOPIDOGREL": 4.946172807737574, "COMBIVIR": 5.191448261231964, "COMIRNATY": 0.1563977605489673, "EFIENT": 30.02469311537381, "ELIQUIS": 0.4036667175159472, "HUMALOG": 0.5513210594199528, "ICLUSIG": 7.074902856258915, "INVIRASE": 31.72654167313184, "IVABRADINE": 41.09930766440105, "JARDIANCE": 0.9827464411972864, "MICARDIS": 2.4278832179268317, "NEXAVAR": 1.093667211924092, "NOT": 4.239119553640717, "PLAVIX": 8.812360712420924, "SPIKEVAX": 0.0700233241792428, "STELARA": 0.7535798836823543, "SUTENT": 0.2699650485858691, "TASIGNA": 5.9346236283024, "TICAGRELOR": 5.615154263583051, "TRELEGY": 3.222385191748701, "VAXZEVRIA": 0.1119369864236737, "ZYPREXA": 1.3462044050161337, "null": 1.1789520355651175}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6350.json
index 81cc3c51633..98321fd4c00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6350.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6350.json
@@ -1 +1 @@
-{"COSENTYX": 227.33299859301476}
\ No newline at end of file
+{"BYDUREON": 43.15537071341788, "FASLODEX": 71.50813924713485, "null": 0.862267173832418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6351.json
index 93a7b794e02..5415e2069f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6351.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6351.json
@@ -1 +1 @@
-{"BONVIVA": 6.178977510161345, "CELECOXIB": 9.44461549207107, "COMIRNATY": 1.0389594596435543, "CRESEMBA": 18.152061890242305, "EBIXA": 12.852828780432867, "ELIQUIS": 1.9592053320887648, "EVISTA": 4.423161684438792, "FASLODEX": 1.856790948096717, "FORSTEO": 4.457912071928293, "LEVOFLOXACIN": 2.3874963180274995, "PEGASYS": 1.0315545439107583, "PROTELOS": 27.176896564318834, "RINVOQ": 4.018172399913326, "ROACTEMRA": 2.5851814088665805, "SIMPONI": 1.4463319013649765, "VAXZEVRIA": 1.381899825469317, "null": 1.830799274281237}
\ No newline at end of file
+{"COMIRNATY": 0.9005398495647808, "VAXZEVRIA": 3.5851390862264005}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6352.json
index 9a6d1db873f..8e5309259bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6352.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6352.json
@@ -1 +1 @@
-{"PROTELOS": 1201.3054046318136}
\ No newline at end of file
+{"null": 1.02079846655359}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6353.json
index 4cd49d03dcb..d7601fbc50a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6353.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6353.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6826831679649588, "COVID19": 1.0500773200124125, "VAXZEVRIA": 3.556748867896201}
\ No newline at end of file
+{"BYDUREON": 52.63683210837285, "COSENTYX": 9.425036748034934, "ENTYVIO": 98.48105345329606, "HIZENTRA": 22.36251436651957, "null": 0.6355169085057336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6354.json
index 22514f5ccc8..5a7ac2d81f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6354.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6354.json
@@ -1 +1 @@
-{"null": 1.070559733320756}
\ No newline at end of file
+{"APIDRA": 15.112935469575186, "BETAFERON": 49.09361632465938, "BYDUREON": 10.635211401316084, "CICLOSPORIN": 1.447880909007077, "CIMZIA": 17.046408770011475, "COMIRNATY": 0.2018584934218498, "COSENTYX": 1.93884442186294, "ENBREL": 3.815697470155639, "FORSTEO": 4.862508655464087, "INSULIN": 2.849633107356301, "LANTUS": 10.296856272706036, "LEVEMIR": 8.4850464379573, "PEGASYS": 1.937514477488942, "PEGINTRON": 3.286596304190232, "PLEGRIDY": 46.10955362881223, "SAXENDA": 28.08518741703107, "SHINGRIX": 5.043506502453442, "SPIKEVAX": 0.4714926198459012, "VAXZEVRIA": 0.3344557635919917, "null": 0.8288184941568638}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6355.json
index b141e2941e3..30412d9bf3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6355.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6355.json
@@ -1 +1 @@
-{"DELAMANID": 93.89526946675883, "OLANZAPINE": 7.324603873684357, "null": 2.4200536385003977}
\ No newline at end of file
+{"AIMOVIG": 1.9219698120534168, "BYDUREON": 3.3290857819010653, "CIMZIA": 0.5260119255937786, "COMIRNATY": 2.413069844742217, "COSENTYX": 0.9036634197842522, "EYLEA": 5.25466761251131, "FASLODEX": 7.942795958596692, "FORSTEO": 2.190581797628984, "HIZENTRA": 3.219393470001869, "HUMALOG": 0.8181841739433885, "LANTUS": 1.7744244433801426, "MMRVAXPRO": 2.01908748162016, "NIMENRIX": 7.488189960521683, "NUCALA": 3.3055130645454462, "SAXENDA": 2.469739815846446, "SHINGRIX": 2.6013380600099656, "SPIKEVAX": 3.039565147383256, "TRULICITY": 5.248700777235031, "VAXZEVRIA": 1.836359045237094, "XOLAIR": 1.1579158221467043, "null": 0.3386764127393709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6356.json
index fa018f6a390..4ddf8cb1d3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6356.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6356.json
@@ -1 +1 @@
-{"null": 1.3805811357358588}
\ No newline at end of file
+{"COMIRNATY": 0.2975196945878058, "null": 0.6921758508107121}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6357.json
index af04e69c6b5..5dda88d8bd3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6357.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6357.json
@@ -1 +1 @@
-{"COMIRNATY": 5.832993491151451}
\ No newline at end of file
+{"null": 0.9771354964150176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6358.json
index 0413cc759f4..3a8751391e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6358.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6358.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0777303884387828, "GARDASIL": 8.609841751386828, "PRIVIGEN": 25.714108279276303}
\ No newline at end of file
+{"ABASAGLAR": 2.1638517789902854, "ACTRAPID": 0.7783419152959041, "AIMOVIG": 1.711624705215235, "ANAKINRA": 0.1172182090422804, "APIDRA": 0.917274934360917, "ARAVA": 0.0608222915894578, "BENLYSTA": 0.2524086531493483, "BETAFERON": 6.455033157458272, "BEXSERO": 1.0462835781609794, "BONVIVA": 0.5640879291089909, "BRINTELLIX": 1.190204093351655, "BUVIDAL": 11.58112562317231, "BYDUREON": 1.556590641132427, "BYETTA": 0.2645240656928042, "CERVARIX": 1.7107760528989084, "CIMZIA": 0.530251575200028, "COMIRNATY": 2.113810548458545, "COSENTYX": 0.3534999303336187, "CYMBALTA": 0.1029188400245961, "DARZALEX": 0.2968081513612893, "DUPIXENT": 0.721736962453549, "ENBREL": 0.729437775179088, "ENOXAPARIN": 0.5275903613001385, "ENTYVIO": 1.5888989045092885, "EVENITY": 2.879290018259928, "EVISTA": 1.47260910904264, "EYLEA": 0.1620628593683455, "FASENRA": 0.5659100564239977, "FASLODEX": 1.0412315334501565, "FENTANYL": 0.0712935516813603, "FIASP": 1.8158452441255992, "FLUCELVAX": 1.051856541401243, "FORSTEO": 4.886822139028914, "GARDASIL": 0.5248718222796535, "HEMLIBRA": 0.9788278960130696, "HIZENTRA": 3.594357504746206, "HUMALOG": 0.3648224080761571, "HUMIRA": 0.1884926905671086, "HYQVIA": 3.9599937984408697, "IDACIO": 2.5795402305388357, "INFANRIX": 2.9684648264043227, "INHIXA": 2.801516410221856, "INSULATARD": 1.6231185977504778, "INSULIN": 0.8112434547816068, "JCOVDEN": 1.55114579298617, "KESIMPTA": 1.2198683777733206, "LANTUS": 0.3339339454622113, "LEVEMIR": 4.856849973283468, "LEVOFLOXACIN": 0.0931064322146504, "LYUMJEV": 13.669935236693926, "MENQUADFI": 9.239081312419753, "MENVEO": 5.153677110621563, "MEPOLIZUMAB": 0.3113332383546349, "METHOTREXATE": 0.0559911544042346, "MIXTARD": 1.2501375863977937, "MMRVAXPRO": 7.60287510516651, "MODERNA": 3.562947684198091, "MOVYMIA": 7.8839659616020095, "NEULASTA": 0.1826811792845775, "NIMENRIX": 7.454712751021688, "NOVORAPID": 0.8890838714248597, "NUCALA": 0.3148446031999804, "OCRELIZUMAB": 0.1430413670829995, "OMALIZUMAB": 0.578317962797891, "PEGASYS": 0.4855345168450594, "PEGINTERFERON": 0.2878415670143127, "PEGINTRON": 1.0414890306633455, "PLEGRIDY": 21.808651621567304, "PREVENAR": 1.4287625963534167, "REBIF": 3.518185216469681, "ROACTEMRA": 2.257966023377921, "ROTARIX": 4.666092149636292, "ROTATEQ": 0.1551927047829724, "SAXENDA": 9.519961246906144, "SHINGRIX": 5.504619205490667, "SIMPONI": 0.242382572292139, "SKYRIZI": 0.904755133141909, "SPIKEVAX": 8.588257047045724, "STELARA": 0.3053116264983445, "SYNAGIS": 0.7581391537643873, "TERIPARATIDE": 1.2184461615198017, "TERROSA": 4.430756947462962, "TOUJEO": 0.9217054129319984, "TOZINAMERAN": 0.0246058523616462, "TREMFYA": 1.645374139284913, "TRESIBA": 0.6948799376914541, "TRULICITY": 5.224260525478492, "TWINRIX": 1.9344551180634653, "VAXZEVRIA": 1.5034896048515545, "VICTOZA": 1.6622720968358538, "XOLAIR": 1.1078238134720362, "ZOSTAVAX": 0.7726659317738851, "ZYPADHERA": 0.2771278980445722, "null": 0.2255734769136914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6359.json
index 1c4eecb4ec5..89c3b6c88a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6359.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6359.json
@@ -1 +1 @@
-{"null": 1.1196148430104418}
\ No newline at end of file
+{"null": 0.9044743737771784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/636.json
index 9a88b52e500..ce1f362d4b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/636.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/636.json
@@ -1 +1 @@
-{"MMRVAXPRO": 8.755671041850686, "null": 12.755959937088909}
\ No newline at end of file
+{"null": 0.7163965810284204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6360.json
index 9869c0071d4..e7aca23ef63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6360.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6360.json
@@ -1 +1 @@
-{"CICLOSPORIN": 8.17574779963936, "VORICONAZOLE": 135.68739277990338}
\ No newline at end of file
+{"AIMOVIG": 9.798627145154551, "BONVIVA": 12.000684036178717, "BYDUREON": 57.4286229874938, "BYETTA": 5.433490753360112, "CIMZIA": 1.216246749462212, "COMIRNATY": 0.194198766821853, "ENTYVIO": 5.787810905398385, "ESOMEPRAZOLE": 8.280655928387487, "FASLODEX": 4.765632015180158, "ILARIS": 166.32935373573164, "LANTUS": 6.496222642995168, "LEVEMIR": 4.395378198891554, "PLEGRIDY": 6.395704767778714, "SIMPONI": 2.066550533713411, "SPIKEVAX": 0.1632075757322577, "VAXZEVRIA": 0.0680132321680064, "ZYPADHERA": 9.81296537995781, "null": 1.7041864714208996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6361.json
index 7cba9f33d75..b3754436671 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6361.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6361.json
@@ -1 +1 @@
-{"AIMOVIG": 2.33155031839947, "AZACITIDINE": 2.110448223421736, "BELIMUMAB": 3.680925238878539, "BEOVU": 5.086577637595925, "CHAMPIX": 1.22756125057967, "COMIRNATY": 1.3528558167165312, "COSENTYX": 1.4318876994379073, "COVID19": 2.552377572771684, "ERENUMAB": 10.02704189224825, "EYLEA": 6.238307229204585, "FLEBOGAMMA": 4.520758543111221, "GARDASIL": 7.178833634746916, "HIZENTRA": 1.91457656856858, "HUMAN": 1.972497984796999, "JETREA": 29.87340712707928, "KIOVIG": 2.932849149058149, "LUXTURNA": 33.10168806744936, "MEKINIST": 1.201661212070977, "MENVEO": 5.293169380409728, "MMRVAXPRO": 1.4559900013224123, "NEVANAC": 7.93625528005635, "NIMENRIX": 1.944578934903714, "PRIVIGEN": 9.29597606194154, "SHINGRIX": 2.156099987719906, "SILDENAFIL": 1.100678890586824, "SPIKEVAX": 1.0667982330418138, "SPINRAZA": 1.4533204803958946, "TOZINAMERAN": 2.357834303746854, "TWINRIX": 1.096888657005788, "VAXZEVRIA": 1.807127333931936, "VFEND": 13.445438039419347, "VIAGRA": 1.2217739014698132, "VORICONAZOLE": 2.191131781915289, "XALKORI": 1.6242836208605094}
\ No newline at end of file
+{"null": 0.9167239559827142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6362.json
index a6007a2ea6e..0aab1166273 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6362.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6362.json
@@ -1 +1 @@
-{"AZILECT": 37.23206085361342, "BEOVU": 17.3774057964473, "BRINTELLIX": 2.167606164064148, "CHAMPIX": 1.739114824163544, "COMIRNATY": 1.060218847771203, "COVID19": 1.9358816286159697, "ERENUMAB": 19.81779697081929, "ESOMEPRAZOLE": 4.334321809544095, "EYLEA": 9.575116758061895, "FASLODEX": 1.881494108099248, "GARDASIL": 1.2888242931387055, "JETREA": 406.7610016231488, "TOZINAMERAN": 2.34194078334566, "VFEND": 14.82579612203931, "VIAGRA": 6.895560408642696, "VORICONAZOLE": 5.974649759405092, "XALKORI": 29.1764804164103}
\ No newline at end of file
+{"null": 4.82782801856178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6363.json
index e3d3e4e9454..f21fb60bb36 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6363.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6363.json
@@ -1 +1 @@
-{"ADENURIC": 3.5830813384944955, "AERIUS": 4.271289004097845, "AIMOVIG": 1.1695391699563442, "ALEMTUZUMAB": 1.3328604786322025, "ANAKINRA": 13.697778504350682, "APROVEL": 2.920089833058851, "ATAZANAVIR": 1.4586277989189418, "AZATHIOPRINE": 1.423872362683516, "BENLYSTA": 1.1284891637256806, "BOSULIF": 1.55255679935935, "BRAFTOVI": 2.1245148090462034, "BRINTELLIX": 1.6630431853228758, "CAPRELSA": 20.36682090496372, "COAPROVEL": 4.377082299707135, "COBIMETINIB": 35.91514071915189, "COSENTYX": 1.217828043145578, "COTELLIC": 48.65962371824853, "DASATINIB": 6.910562087939298, "DESLORATADINE": 5.9867980874682, "EMTRIVA": 15.25648437215026, "ENBREL": 1.130274227345185, "ENTYVIO": 1.155644083612168, "ESBRIET": 42.81341624115025, "EXFORGE": 1.1825303493374295, "GARDASIL": 1.9652038248685704, "IRBESARTAN": 2.862349617962733, "KAFTRIO": 1.1833625624190454, "KEPPRA": 1.0075384410991046, "LEVOFLOXACIN": 1.3748565376675073, "METHOTREXATE": 2.380496607127948, "MICARDISPLUS": 10.022856636163448, "MULTAQ": 6.33796335013457, "MYCOPHENOLATE": 1.3326730875207922, "OLYSIO": 61.43671189451053, "PANTOPRAZOLE": 1.5018409415706775, "PEGASYS": 1.4097652230545314, "PEGINTRON": 1.168158584489862, "PIRFENIDONE": 81.87302339553328, "RASILEZ": 1.8690756487807123, "RIBAVIRIN": 1.4885092812979226, "RUBRACA": 6.377257826963176, "SIMEPREVIR": 23.011967925880302, "SOVALDI": 2.332324622538988, "VEMURAFENIB": 36.187932257270695, "VFEND": 31.180583209106384, "VORICONAZOLE": 42.82782057483317, "XOLAIR": 1.5093300071715747, "ZELBORAF": 57.499578519567216, "null": 1.3270034625435363}
\ No newline at end of file
+{"ABASAGLAR": 2.4163040735604557, "APIDRA": 2.0737517156467558, "BETAFERON": 3.429145212862429, "BRINTELLIX": 2.916904876901613, "BYDUREON": 0.6626741738432944, "CIMZIA": 0.3124727268227837, "CLOPIDOGREL": 0.2283970143868333, "COMIRNATY": 3.773894517058901, "COSENTYX": 0.3924392934823938, "ELIQUIS": 0.1619917017068816, "ENOXAPARIN": 3.350903676103481, "FASLODEX": 2.805901824263979, "FORSTEO": 7.84501235718108, "GARDASIL": 0.1644825925148515, "HUMALOG": 0.3863301872096171, "INHIXA": 21.13499359018867, "INSULIN": 0.3844259279786534, "LANTUS": 0.8642133884722029, "LEVEMIR": 0.6840680457793153, "MEPOLIZUMAB": 1.3555848415245697, "MMRVAXPRO": 1.0866868693808045, "MODERNA": 0.3212935734381498, "MOVYMIA": 26.99942879771171, "NIMENRIX": 0.8175196296287761, "NUCALA": 0.3225637365361581, "NUTROPINAQ": 67.45453114642442, "OMALIZUMAB": 0.3895809024147965, "PEGASYS": 0.0979964549378465, "PEGINTRON": 0.207852370136813, "PLAVIX": 0.3167106959005023, "PLEGRIDY": 4.66596807066349, "ROACTEMRA": 1.2141305029502147, "SAXENDA": 2.968113775830008, "SHINGRIX": 0.2686792949518373, "SIMPONI": 0.750185881749279, "SPIKEVAX": 4.827749771231789, "TRULICITY": 3.0528603582424934, "VAXZEVRIA": 1.9397083349735968, "XOLAIR": 0.5113189384007911, "null": 0.2486052892869777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6364.json
index a427886c857..bba697f0236 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6364.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6364.json
@@ -1 +1 @@
-{"null": 1.698193259516354}
\ No newline at end of file
+{"ABASAGLAR": 19.351303492751885, "ACLASTA": 14.555397313196542, "AIMOVIG": 10.125369061216178, "APIDRA": 9.320203226997885, "ARANESP": 3.259520893363877, "BENLYSTA": 5.388953773604058, "BETAFERON": 7.617306709067428, "BYDUREON": 52.31208787947631, "BYETTA": 5.426434187367427, "CICLOSPORIN": 0.4268932716106174, "CIMZIA": 2.10987748534042, "CLOPIDOGREL": 1.5574530934563493, "COMIRNATY": 0.1012169558789416, "COSENTYX": 4.675220775828595, "ELIQUIS": 0.9013084156487762, "ENBREL": 0.4338205630014897, "ENOXAPARIN": 9.02557630810152, "EVISTA": 11.608507023258948, "EYLEA": 4.886709184530151, "FASENRA": 3.4790447578818933, "FASLODEX": 2.9686186307671503, "FORSTEO": 15.54348744820253, "GARDASIL": 0.295720252304581, "HIZENTRA": 1.5096143656595726, "HUMALOG": 5.5163105295839365, "HUMIRA": 0.6242921853394787, "INHIXA": 25.271097339249344, "INSULIN": 1.3589912787382774, "INTEGRILIN": 13.002030102046518, "KESIMPTA": 5.423620175613192, "LANTUS": 13.883980830812169, "LEVEMIR": 3.2028111417427683, "MEPOLIZUMAB": 1.0901039095751477, "METHOTREXATE": 0.489828716868735, "NOVORAPID": 1.1805605457551094, "NUCALA": 0.8614144793131543, "OMALIZUMAB": 2.417307957838827, "OMNITROPE": 21.70108096101536, "PEGASYS": 0.7543320657348742, "PEGINTRON": 1.290971750839649, "PLAVIX": 1.5880624756780637, "PLEGRIDY": 62.8092867143474, "PROPRANOLOL": 4.045564566223877, "ROACTEMRA": 2.9186781505040065, "SIMPONI": 12.920205337188948, "SKYRIZI": 7.483320503453508, "SOMATROPIN": 9.86754881187074, "SPIKEVAX": 0.1063580129912657, "STELARA": 0.8938239193671483, "TERROSA": 26.57497786214627, "TOUJEO": 6.315330031783683, "TREMFYA": 10.528913431687643, "TRULICITY": 16.92174243822442, "VAXZEVRIA": 0.17023578409228, "VICTOZA": 3.2963704754508103, "XOLAIR": 0.9198574815927164, "ZYPADHERA": 8.814872713036596, "null": 0.9269426471966709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6365.json
index b2efebd1e31..bd552fc4a5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6365.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6365.json
@@ -1 +1 @@
-{"null": 4.826380696809855}
\ No newline at end of file
+{"null": 0.6579458467610275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6366.json
index 6353020e17e..ac8b48ebc12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6366.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6366.json
@@ -1 +1 @@
-{"CHAMPIX": 23.912197265454942, "CYMBALTA": 4.566041079955316, "FYCOMPA": 70.48429610073784, "JARDIANCE": 2.784938184573706, "KEPPRA": 7.961523478268476, "LATUDA": 13.267118074208542, "PEGASYS": 2.0237567444924363, "SUBOXONE": 8.063064019118448, "ZYPREXA": 3.459840721567651, "null": 2.553016376091892}
\ No newline at end of file
+{"AFINITOR": 4.325282709791495, "AIMOVIG": 4.933587914480797, "ANAKINRA": 6.649011176515492, "APIDRA": 16.829367419387985, "ARAVA": 0.3368041210082948, "COMIRNATY": 0.3881711088678868, "ENBREL": 2.5969490375590483, "ENTYVIO": 8.125794973264224, "FASLODEX": 4.179953648659973, "FIASP": 18.08824697358781, "FORSTEO": 2.041207973284883, "HUMALOG": 3.5749155443804512, "INSULIN": 2.5615583574148046, "LANTUS": 1.6278440352018997, "LEVEMIR": 44.45017244919512, "NOVORAPID": 4.816500628940478, "PEGASYS": 0.7313406100797408, "ROACTEMRA": 11.38261021857491, "SAXENDA": 80.45829811070433, "SPIKEVAX": 2.695291636906402, "TRULICITY": 32.86994266286161, "VAXZEVRIA": 0.5980540059286231, "VICTOZA": 9.235868772515715, "null": 0.283081311169835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6367.json
index 6be8fadd342..4c076974747 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6367.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6367.json
@@ -1 +1 @@
-{"APIXABAN": 1.457914463905314, "CHAMPIX": 2.844249294995618, "COMIRNATY": 1.1663809503686469, "CYMBALTA": 1.914884269376273, "ESOMEPRAZOLE": 152.45535552702785, "EVENITY": 15.201333457368364, "EXFORGE": 2.4902315446560466, "FORXIGA": 2.2544684170706257, "GARDASIL": 1.0563284607445784, "INLYTA": 2.158643434180084, "JANUVIA": 1.815139394075142, "JARDIANCE": 1.6595432447057918, "JEVTANA": 7.954452546646241, "KEYTRUDA": 3.0615832036279764, "LANTUS": 1.9728274037609077, "LATUDA": 3.953999088860821, "METFORMIN": 29.53439335498188, "NEXAVAR": 2.456040975280282, "NUCALA": 1.817486919720328, "OFEV": 9.419122685306077, "OPDIVO": 3.407527251903232, "OPSUMIT": 1.088924323822517, "STIVARGA": 2.156306249538904, "XELJANZ": 1.4758517012170262, "XOFIGO": 6.917627610377852, "XTANDI": 2.315673831297754}
\ No newline at end of file
+{"null": 3.440318901667623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6368.json
index 2fa68b7ca73..bd4644376a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6368.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6368.json
@@ -1 +1 @@
-{"ABATACEPT": 2.921572667942407, "AVANDIA": 1.1743500048898214, "PLAVIX": 8.682241137144018, "null": 9.086383900683314}
\ No newline at end of file
+{"LEVEMIR": 48.59655869007735, "null": 0.481739723213371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6369.json
index 3aad96604ac..92a84412a52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6369.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6369.json
@@ -1 +1 @@
-{"SPINRAZA": 263.044119806319}
\ No newline at end of file
+{"COMIRNATY": 3.2563028841418657, "FASLODEX": 7.181490005548178, "GARDASIL": 1.6310319531892996, "SIMPONI": 2.6180840220501693, "SPIKEVAX": 2.261289415382543, "VAXZEVRIA": 1.7544972156087375, "null": 0.3667051389941538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/637.json
index f1b8ce45e81..e3cb6640995 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/637.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/637.json
@@ -1 +1 @@
-{"ALDARA": 56.72354895590348, "AMELUZ": 160.43156103925915, "BUPRENORPHINE": 4.574628984404338, "EVRA": 41.520771892426325, "QUTENZA": 592.120629817139, "null": 7.226662435139376}
\ No newline at end of file
+{"ASPARAGINASE": 319.67728143141954, "null": 0.1877053021953632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6370.json
index 71218f8e74d..e83ae9a692d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6370.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6370.json
@@ -1 +1 @@
-{"null": 2.1997009292346097}
\ No newline at end of file
+{"AIMOVIG": 39.541702712060136, "COMIRNATY": 0.4911918880104061, "VAXZEVRIA": 1.9505233814036569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6371.json
index e79ab8e0d98..c8e5b2db12f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6371.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6371.json
@@ -1 +1 @@
-{"null": 1.8582657088792327}
\ No newline at end of file
+{"AFINITOR": 0.9026861010351596, "AIMOVIG": 0.4350195846564632, "APIDRA": 2.716486230393913, "BETAFERON": 19.87274297123187, "BUVIDAL": 14.16411226087345, "BYDUREON": 5.540445600792123, "CIMZIA": 0.2646123501642975, "COMIRNATY": 1.3935731591207932, "COSENTYX": 0.329789165573419, "FASLODEX": 7.819264698100782, "FENTANYL": 0.4142832175868822, "FORSTEO": 0.9114198117291652, "GARDASIL": 1.052666772581214, "HIZENTRA": 5.374292914229049, "HUMALOG": 1.909413143177831, "INSULIN": 3.461988477181094, "LANTUS": 1.8283463063424856, "LEVEMIR": 11.30526718258914, "LYUMJEV": 17.396373382693593, "MENVEO": 7.687753755446627, "MMRVAXPRO": 1.6906122983016545, "MODERNA": 0.3970170095998745, "NIMENRIX": 1.6462692267957588, "NOVORAPID": 3.4811050536648627, "ORENCIA": 10.42593001277369, "PEGASYS": 0.1371181537554634, "PEGINTRON": 0.964514971830079, "PLEGRIDY": 7.857432252556512, "ROACTEMRA": 1.1490592528548813, "SAXENDA": 5.970067784471712, "SHINGRIX": 2.7311188812816414, "SPIKEVAX": 8.539854820767324, "STELARA": 0.2321256749397905, "SUBOXONE": 0.4853901920664356, "TREMFYA": 2.6825358952367995, "TRULICITY": 4.073613948589225, "TWINRIX": 3.901989884982667, "VAXZEVRIA": 1.287932579146225, "VICTOZA": 1.4396990968247565, "XOLAIR": 0.4595231991646497, "ZOSTAVAX": 0.6276771844507796, "ZYPADHERA": 1.6867305340622971, "null": 0.3248924804344293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6372.json
index d8483badd59..16f202f3a72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6372.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6372.json
@@ -1 +1 @@
-{"null": 3.1554650401827407}
\ No newline at end of file
+{"APIDRA": 5.353865104791541, "BETAFERON": 69.9395905386055, "BYDUREON": 14.209018856908925, "CIMZIA": 1.736982216507658, "COMIRNATY": 0.3150457482596291, "FASLODEX": 9.307755579827322, "HIZENTRA": 11.658155599265363, "HUMALOG": 2.6273955430601976, "LANTUS": 3.2610596989295337, "PEGASYS": 3.627809809232158, "PEGINTRON": 6.618334975687935, "SPIKEVAX": 0.7020726322482158, "VAXZEVRIA": 0.4999483759212172, "null": 1.1579617660072214}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6373.json
index 0c417fc9f9f..630d597abf0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6373.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6373.json
@@ -1 +1 @@
-{"null": 2.216280710420783}
\ No newline at end of file
+{"ACLASTA": 1.5255942283996875, "AIMOVIG": 0.0629851095181491, "APIDRA": 0.3289699685508512, "BENEPALI": 7.418102639341672, "BETAFERON": 3.108856076207028, "BRINTELLIX": 3.5173460119468154, "BUVIDAL": 2.3447024669156016, "BYDUREON": 0.4100725518732144, "CIMZIA": 0.0356434387709541, "COMIRNATY": 3.464210329759271, "EYLEA": 0.2709637756169761, "FASLODEX": 0.343026539709705, "FIASP": 1.1583130464575566, "GARDASIL": 0.1609376193092416, "HIZENTRA": 0.3586360878726745, "HUMALOG": 0.0394703423925596, "INFANRIX": 0.7191137919397586, "LANTUS": 0.0329053844624305, "LEVEMIR": 0.3938282685281415, "MENVEO": 0.9247660565773002, "MMRVAXPRO": 4.126982063857407, "MODERNA": 0.3064797025759471, "NIMENRIX": 8.70069368119491, "PEGASYS": 0.0373369493322526, "PEGINTRON": 0.1550741886981788, "PLEGRIDY": 0.7267455827329328, "ROACTEMRA": 0.2604544088433559, "SAXENDA": 0.4642712392143559, "SHINGRIX": 0.8405611731717473, "SPIKEVAX": 10.04311151245854, "TRULICITY": 0.2615584850582658, "TWINRIX": 0.4835928796909644, "VAXZEVRIA": 2.415863913260534, "XOLAIR": 0.1553495110783708, "ZOSTAVAX": 0.0873610342235589, "null": 0.0757095561110872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6374.json
index f4c579300ff..7d628aafdf3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6374.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6374.json
@@ -1 +1 @@
-{"null": 9.575409445861082}
\ No newline at end of file
+{"APIDRA": 12.293329061010942, "BYDUREON": 21.185717657297623, "FASLODEX": 23.01710109648364, "HUMALOG": 5.367894386409123, "LANTUS": 11.465413385743068, "PLEGRIDY": 53.56760734289673, "TRULICITY": 23.00373230491704, "VAXZEVRIA": 0.1788107718825199, "null": 1.26826868373604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6375.json
index a81b0114c22..2fc5f3700d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6375.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6375.json
@@ -1 +1 @@
-{"null": 2.6556073102073143}
\ No newline at end of file
+{"AIMOVIG": 7.574379720136462, "CIMZIA": 3.7857816576239913, "COMIRNATY": 0.0867051910423484, "FASLODEX": 8.656815300448518, "FIASP": 40.72858039073311, "GARDASIL": 3.071041323548865, "HIZENTRA": 12.611525085319895, "HUMALOG": 2.584489565798849, "LANTUS": 2.877395063931004, "PLEGRIDY": 25.929932059534416, "SAXENDA": 48.73667426736208, "SPIKEVAX": 0.6711658116129033, "TRULICITY": 13.961167707962874, "VAXZEVRIA": 0.2117027829135746, "null": 0.9305811887508112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6376.json
index 2eaa598f27b..9007ce5308b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6376.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6376.json
@@ -1 +1 @@
-{"null": 1.53567740245871}
\ No newline at end of file
+{"null": 7.131777242974785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6377.json
index 570c29dc267..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6377.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6377.json
@@ -1 +1 @@
-{"AFINITOR": 1.1090881420079746, "AVASTIN": 3.009323132020194, "BEVACIZUMAB": 3.023676281123968, "BIKTARVY": 14.009123986857192, "COSENTYX": 2.1484689460044644, "DEXAMETHASONE": 1.338979179651532, "EXFORGE": 1.946677866082773, "FORSTEO": 1.8673138235509776, "KISQALI": 5.251146733616541, "LEFLUNOMIDE": 11.889443453400656, "LEVOFLOXACIN": 1.008232609582165, "MEKINIST": 1.7534419756904116, "OPTIMARK": 8.106690691395034, "PEGASYS": 1.095903617983326, "SUTENT": 2.337134739937951, "VOTRIENT": 3.5697638270200724, "XOLAIR": 2.2232093522323515, "null": 2.123934774645688}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6378.json
index 02479b11a55..f470291a0f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6378.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6378.json
@@ -1 +1 @@
-{"ABILIFY": 6.719464659881618, "BUPRENORPHINE": 6.007709716303477, "COMIRNATY": 1.0182768479909297, "COVID19": 2.654475626836231, "FENTANYL": 11.250486260647172, "SPIKEVAX": 1.1947273934183458, "SUBOXONE": 5.516033533357287, "TOZINAMERAN": 2.019168231434914, "VAXZEVRIA": 1.3900442270664304}
\ No newline at end of file
+{"COMIRNATY": 0.5489473924900842, "MODERNA": 34.2853694186257, "SPIKEVAX": 1.790642435808837, "null": 0.5365168473202504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6379.json
index 1a316ef3621..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6379.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6379.json
@@ -1 +1 @@
-{"HUMIRA": 57.69823251673791}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/638.json
index 132b2a2e7cb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/638.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/638.json
@@ -1 +1 @@
-{"QUTENZA": 443.6786496626767, "SPIKEVAX": 1.1501093734408383, "null": 3.661475534210249}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6380.json
index 1596e10b98f..20d4b864835 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6380.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6380.json
@@ -1 +1 @@
-{"GARDASIL": 31.89632822653764}
\ No newline at end of file
+{"null": 2.778200114793397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6381.json
index 27abe90f1b5..f67b29e81df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6381.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6381.json
@@ -1 +1 @@
-{"null": 3.5103262795406023}
\ No newline at end of file
+{"COMIRNATY": 4.656238343019606, "SPIKEVAX": 2.97726139593493, "VAXZEVRIA": 1.6260910191985924, "null": 0.1072201749159709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6382.json
index bc34b549a23..cf937cf86ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6382.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6382.json
@@ -1 +1 @@
-{"null": 1.2723219839493107}
\ No newline at end of file
+{"COMIRNATY": 2.0587525758959475, "SPIKEVAX": 1.9647286798002424, "VAXZEVRIA": 2.9514671964227617, "null": 0.5912998819310886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6383.json
index f94a11c9ce3..977de995704 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6383.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6383.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 19.083623760488734, "OPDIVO": 66.88881843522914}
\ No newline at end of file
+{"COMIRNATY": 0.8949597363781386, "MODERNA": 78.01761768383675, "SPIKEVAX": 1.4087390928283745, "VAXZEVRIA": 0.8020844888454317, "null": 1.197362696133965}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6384.json
index f760f971f62..4a864d3313b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6384.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6384.json
@@ -1 +1 @@
-{"LANTUS": 2.7059341991172, "null": 3.065592630020129}
\ No newline at end of file
+{"null": 0.7056531463719815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6385.json
index a0d9759fe3b..b39ec03a174 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6385.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6385.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 4.303349556426392, "CYMBALTA": 3.3243704632739943, "HYDROCORTISONE": 18.686926283494053, "OLANZAPINE": 5.49796598715079, "SOMATROPIN": 63.016160763225535, "ZYPREXA": 3.432428826828059, "null": 2.191161186509677}
\ No newline at end of file
+{"null": 4.770015538267414}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6386.json
index fbf4bf88277..fcbc50c5dca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6386.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6386.json
@@ -1 +1 @@
-{"null": 3.3500130170480302}
\ No newline at end of file
+{"COMIRNATY": 7.502377896940629, "SPIKEVAX": 3.4593882654886223, "VAXZEVRIA": 0.3168891492920634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6387.json
index fba54b6cf0c..804f719c47f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6387.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6387.json
@@ -1 +1 @@
-{"null": 8.825496783869223}
\ No newline at end of file
+{"SPIKEVAX": 2.2229872512204167, "null": 0.4549782352129193}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6388.json
index 76135d0b4a7..a018d1fc781 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6388.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6388.json
@@ -1 +1 @@
-{"ATRIPLA": 2.7535466194941174}
\ No newline at end of file
+{"ABASAGLAR": 10.178046675029629, "AFINITOR": 2.746473342139388, "AIMOVIG": 1.6338886547631382, "APIDRA": 2.426964802831161, "BETAFERON": 14.03604619650286, "BEXSERO": 7.692400676067793, "BUVIDAL": 132.48201321544602, "BYDUREON": 52.97665395344087, "BYETTA": 1.9940795472936017, "CIMZIA": 0.8990812165668235, "COMIRNATY": 0.2986509584682101, "COSENTYX": 3.206319109432782, "ENBREL": 0.5995376033071456, "EVENITY": 4.571729353193205, "FASLODEX": 19.18460041908295, "FIASP": 9.34902879851446, "FORSTEO": 2.266437151881663, "GARDASIL": 0.9517023179286356, "HIZENTRA": 5.0829962713902646, "HUMALOG": 5.393240239996179, "INSULIN": 1.5568408472154764, "LANTUS": 4.138530758909317, "LEVEMIR": 23.578521213624693, "LUTETIUM": 24.14235755997068, "LYUMJEV": 43.04204303733281, "NIMENRIX": 1.8154164121604237, "NOVORAPID": 3.906916806360983, "OCRELIZUMAB": 6.773426722133022, "PEGASYS": 0.2697357811474238, "PLEGRIDY": 3.721986659731683, "SAXENDA": 11.623357067156014, "SHINGRIX": 0.6675274286777747, "SIMPONI": 1.248958372113662, "SPIKEVAX": 0.5608686799679775, "STELARA": 2.021899809295095, "TOUJEO": 4.058109619468821, "TOZINAMERAN": 0.1540243720376717, "TREMFYA": 2.556052783999356, "TRULICITY": 16.36851395854585, "VAXZEVRIA": 2.753678409102316, "VICTOZA": 3.4648719920413877, "XOLAIR": 1.6334566085765494, "ZOSTAVAX": 1.6239489491003656, "ZYPADHERA": 3.757335327248045, "null": 0.5928094219582434}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6389.json
index 93ecc359c02..d99cd461bc8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6389.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6389.json
@@ -1 +1 @@
-{"TOZINAMERAN": 3.260185664789124}
\ No newline at end of file
+{"COMIRNATY": 3.902114705549993, "SPIKEVAX": 4.5477537080392665, "VAXZEVRIA": 1.9975677141058263, "null": 0.159311338292498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/639.json
index 0b846df7f2b..31e92af638f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/639.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/639.json
@@ -1 +1 @@
-{"null": 4.109071196305052}
\ No newline at end of file
+{"CLOPIDOGREL": 12.6763895795205, "ELIQUIS": 7.794150695718074, "METHOTREXATE": 18.62506321705894, "null": 0.5140132321674769}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6390.json
index c1aabea5f94..14a22b07ff8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6390.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6390.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0795004013393938}
\ No newline at end of file
+{"COMIRNATY": 5.929580167540494, "SPIKEVAX": 2.9569596923600248, "VAXZEVRIA": 1.431813532138834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6391.json
index 14ad3ab554a..6254a3e57e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6391.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6391.json
@@ -1 +1 @@
-{"COMIRNATY": 5.87389143338205, "GARDASIL": 3.54756628266662, "SPIKEVAX": 1.8427821505603288, "TOZINAMERAN": 2.819630884438891}
\ No newline at end of file
+{"BETAFERON": 242.46496516396616, "BYDUREON": 3.622952060290892, "ENOXAPARIN": 14.4345982223795, "FASLODEX": 26.261967838161603, "FULVESTRANT": 8.738115782611867, "HIZENTRA": 13.804170224412935, "LANTUS": 1.7417864822235896, "PEGINTERFERON": 6.651264214852836, "PEGINTRON": 41.4015605968823, "PLEGRIDY": 8.0843466617031, "REBETOL": 24.38215089986352, "SUBOXONE": 3.434237309252293, "null": 2.139301083608602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6392.json
index b20c18ee8fa..f67bb4fccae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6392.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6392.json
@@ -1 +1 @@
-{"ADALIMUMAB": 4.959263203251201, "CICLOSPORIN": 10.61846079233384, "ICLUSIG": 53.93698520196627}
\ No newline at end of file
+{"null": 1.1042497054935116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6393.json
index 06bb368801a..2bc2709530f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6393.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6393.json
@@ -1 +1 @@
-{"null": 1.872168776398728}
\ No newline at end of file
+{"APIDRA": 7.26497215940671, "BETAFERON": 16.28219088088887, "BUVIDAL": 101.10611988042058, "BYDUREON": 247.82497367002492, "CABOTEGRAVIR": 85.92336302585137, "COMIRNATY": 0.0957673125977536, "ENOXAPARIN": 6.429612281330059, "FASLODEX": 20.345701460816827, "FORSTEO": 2.0263454077594787, "GARDASIL": 1.2071872440217442, "HIZENTRA": 7.392084505112527, "HUMALOG": 1.3880709118245045, "INSULIN": 6.899289898787941, "LANTUS": 6.113096633344028, "LEVEMIR": 12.985660443342852, "SPIKEVAX": 0.1780968441589505, "TRULICITY": 6.3388732274982456, "VAXZEVRIA": 0.2081066084847525, "null": 0.947517020706353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6394.json
index e2ba4f6b3ab..5a633907a2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6394.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6394.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 18.21596402642002, "CYMBALTA": 4.30131504773034, "SUBOXONE": 21.271682447714632, "null": 1.3039377145252045}
\ No newline at end of file
+{"AIMOVIG": 0.8951904364291062, "APIDRA": 3.332276190692532, "ARAVA": 0.3738116700710823, "BETAFERON": 5.977001823109292, "COMIRNATY": 2.7648947302024665, "ENTYVIO": 2.946697413264264, "FASLODEX": 1.4811428269857003, "GARDASIL": 0.5247454392392644, "HIZENTRA": 2.160613153785988, "LEVEMIR": 4.431426350858566, "MENVEO": 17.44997447786477, "MMRVAXPRO": 2.452587183616913, "MODERNA": 3.20219690623795, "NIMENRIX": 4.467100311926894, "PLEGRIDY": 5.233809979072314, "ROACTEMRA": 4.682411581971213, "ROTARIX": 67.9143168822047, "SAXENDA": 2.100802002346716, "SHINGRIX": 1.442804277366847, "SOMAVERT": 48.44739766612511, "SPIKEVAX": 2.061423246041963, "STELARA": 0.6705033818452452, "TREMFYA": 4.772554340640084, "TRULICITY": 5.714596057391035, "VAXZEVRIA": 0.7082208614954685, "XOLAIR": 2.7873576366503343, "null": 0.9680473948359244}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6395.json
index e0956e9c2b6..51cb9cb8a31 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6395.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6395.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 19.89339561215432, "COMBIVIR": 24.546871304112383, "EPIVIR": 34.128575768762055, "KEPPRA": 5.102457531575547, "null": 1.5371245785580427}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6396.json
index 76afbfb61ff..118652c7cfb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6396.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6396.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 529.6759586755849}
\ No newline at end of file
+{"null": 4.992427109914473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6397.json
index 1c70de7ef7c..6452727eb8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6397.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6397.json
@@ -1 +1 @@
-{"null": 1.866169029069192}
\ No newline at end of file
+{"COMIRNATY": 0.6028528095243728, "SPIKEVAX": 1.0053272164370497, "null": 0.7379100413294987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6398.json
index 680506ab5c7..d7d0fae8741 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6398.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6398.json
@@ -1 +1 @@
-{"CEFTAROLINE": 1995.0411285213304, "null": 1.7929340154451503}
\ No newline at end of file
+{"COMIRNATY": 3.042601448080089, "FORSTEO": 3.4597242153714096, "GARDASIL": 2.2674519405757576, "MODERNA": 6.336862328560651, "SHINGRIX": 3.3985864868480173, "SPIKEVAX": 2.544697704978642, "VAXZEVRIA": 1.2387329098099136, "null": 0.3329666600274695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6399.json
index b5f72c83f72..80b9f3dafb8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6399.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6399.json
@@ -1 +1 @@
-{"FENTANYL": 81.05291178788833, "null": 1.2106190070076248}
\ No newline at end of file
+{"null": 12.433745810109867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/64.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/64.json
index e3cdc0c4f76..227e719e09c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/64.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/64.json
@@ -1 +1 @@
-{"ARAVA": 3.689549793530921, "CICLOSPORIN": 17.372580702754462, "null": 1.2835800561208623}
\ No newline at end of file
+{"ABILIFY": 3.654288968139205, "ARIPIPRAZOLE": 3.233028517882534, "BIKTARVY": 13.905583323339515, "BRINTELLIX": 3.0102480819723496, "COMIRNATY": 0.2728795603528169, "DESLORATADINE": 44.96482191199119, "FORSTEO": 3.4480330966570056, "GENVOYA": 42.45953955944619, "INVEGA": 36.4521364922043, "KEPPRA": 1.1687221691736556, "OLANZAPINE": 11.24600716347155, "RINVOQ": 5.844719752000349, "SPIKEVAX": 0.0877075731949452, "TOZINAMERAN": 0.3279095636598063, "VAXZEVRIA": 0.2634832652149743, "ZYPREXA": 8.664802590360368, "null": 1.9274173325195296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/640.json
index 0088e9a524d..0a917175ed9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/640.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/640.json
@@ -1 +1 @@
-{"AVAMYS": 8.26798761133523, "IBUPROFEN": 5.189039386941863, "KEPPRA": 2.399066587772965, "KYMRIAH": 11.735727412449387, "MICARDIS": 16.189786321376353, "null": 1.8600395844359932}
\ No newline at end of file
+{"ABACAVIR": 0.140370020968263, "ABASAGLAR": 0.5145686935839817, "ABILIFY": 0.0722226491588214, "ACE": 9.675285477397145, "ACTRAPID": 0.8743875349042555, "ADALIMUMAB": 0.0229561953060779, "ADENURIC": 0.6668701268105052, "AERIUS": 3.120014127364198, "AFINITOR": 1.339445854038719, "AIMOVIG": 0.2370622227959212, "ALIMTA": 0.3055071217572376, "ANORO": 0.2296808703956291, "APIDRA": 0.8853174609252278, "APIXABAN": 3.734436801483392, "APROVEL": 6.318404623719389, "ARANESP": 0.1836860866075346, "ARAVA": 0.0617871758794235, "ARIPIPRAZOLE": 0.1222948841119581, "ASPARAGINASE": 0.3851475054153915, "ATAZANAVIR": 0.2774665342495173, "ATRIPLA": 0.0193232711476081, "AUBAGIO": 0.3154292997503588, "AVAMYS": 0.3678044318123394, "AVANDIA": 0.096738925811888, "BENLYSTA": 0.5261229411508322, "BETMIGA": 0.9646609769825998, "BEXSERO": 2.642333193522215, "BIKTARVY": 0.4216900850401335, "BONVIVA": 1.103493064862073, "BOSULIF": 0.3272923883409454, "BOTULINUM": 16.004683432179913, "BRIDION": 2.5660743754284328, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6400.json
index 5ef89597d72..9ae1b65c8c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6400.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6400.json
@@ -1 +1 @@
-{"null": 5.973252903537125}
\ No newline at end of file
+{"SPIKEVAX": 0.8884794630549419, "TRULICITY": 30.059265813213, "VAXZEVRIA": 0.5074203895350425, "null": 0.520899031913128}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6401.json
index 27f1e846c1b..4d2c6bf8b61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6401.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6401.json
@@ -1 +1 @@
-{"NEXAVAR": 38.92430833213189, "STIVARGA": 51.83478744048034, "SUTENT": 14.82722095857907}
\ No newline at end of file
+{"ABASAGLAR": 4.789358893265909, "AFINITOR": 0.1362868561276987, "AIMOVIG": 2.2315076517370542, "APIDRA": 1.801436725810878, "BETAFERON": 0.9502093282566172, "BRINTELLIX": 1.2146639813907656, "BUVIDAL": 16.98901595649729, "BYDUREON": 5.923686443732716, "BYETTA": 0.7049688253705881, "CIMZIA": 0.4355432155413122, "COMIRNATY": 1.866807903862934, "COSENTYX": 0.4964512172794982, "DULAGLUTIDE": 4.156081596373442, "ENBREL": 1.3748905885052098, "ENOXAPARIN": 0.5537143909780845, "ENTYVIO": 2.282432487085737, "EVENITY": 1.4775364295635702, "FASENRA": 0.3678412591069056, "FASLODEX": 2.517106273189357, "FENTANYL": 0.1649902201024431, "FIASP": 3.2227400204039616, "FORSTEO": 1.254838885663739, "GARDASIL": 0.3259218091123686, "HIZENTRA": 4.276693754233053, "HUMALOG": 0.956618936388247, "HUMIRA": 0.7899242041178759, "INHIXA": 9.18505094045733, "INSULATARD": 5.926416077490024, "INSULIN": 1.6159411954412497, "KESIMPTA": 1.517069498119927, "LANTUS": 0.8768570262045604, "LEVEMIR": 8.739352866305511, "LEVOFLOXACIN": 0.3117580591882704, "LYUMJEV": 13.984652241906804, "MENVEO": 2.2141612325441598, "MEPOLIZUMAB": 0.7721137651299346, "METHOTREXATE": 0.1370965250468656, "MMRVAXPRO": 1.147226296622738, "MODERNA": 1.854562801082361, "NIMENRIX": 7.378142051352186, "NOVOMIX": 13.209800082830222, "NOVORAPID": 1.6994453716549274, "NUCALA": 0.581376266392962, "OMALIZUMAB": 0.5864441075600549, "PEGASYS": 0.3566753878748058, "PEGINTRON": 0.5483290683581482, "PLEGRIDY": 11.829091263186625, "PREVENAR": 1.1966199284830188, "ROACTEMRA": 2.565550184029449, "SAXENDA": 19.901706532493257, "SHINGRIX": 2.198483517006423, "SIMPONI": 0.2515881939371542, "SPIKEVAX": 9.104677167805544, "STELARA": 0.2248608553161899, "TOUJEO": 1.862293073839281, "TOZINAMERAN": 0.0348417536781045, "TREMFYA": 2.066827978498037, "TRESIBA": 3.294831200287436, "TRULICITY": 14.331781003929477, "TWINRIX": 1.8713052705944828, "VAXZEVRIA": 1.298819161558704, "VICTOZA": 3.7415518322522336, "XOLAIR": 1.6269065509757004, "ZOSTAVAX": 0.5879792580812302, "null": 0.1934812905893737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6402.json
index f537c6a9090..a78ec095ec3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6402.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6402.json
@@ -1 +1 @@
-{"null": 1.2476389963413008}
\ No newline at end of file
+{"SPIKEVAX": 0.8757844101682217, "null": 0.6956146435995719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6403.json
index 22852a74f8c..cd8e9a31bb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6403.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6403.json
@@ -1 +1 @@
-{"AMGEVITA": 1020.8310174406388, "BUPRENORPHINE": 7.228054978638736, "CHOLESTAGEL": 484.1335908908842, "COSENTYX": 3.963878381610708, "ENBREL": 9.453008515832062, "HARVONI": 14.933772300369856, "LEVOFLOXACIN": 5.184190944825141, "OPTIMARK": 5.216795573526623, "TOZINAMERAN": 1.152423995690964, "XELJANZ": 2.57610753350694, "ZOSTAVAX": 3.979053448573323, "null": 1.0703020729970498}
\ No newline at end of file
+{"ABASAGLAR": 7.09270767931323, "AIMOVIG": 6.682740791958593, "BENLYSTA": 1.646710060625174, "BETAFERON": 8.279254956593867, "BUVIDAL": 17.38515844174335, "BYDUREON": 3.8689481682187408, "BYETTA": 0.9009716926061956, "CIMZIA": 2.6904884098333994, "COMIRNATY": 0.5093092216619081, "COSENTYX": 0.6296649655395974, "ENBREL": 3.4023140761041013, "ENOXAPARIN": 4.274980222337302, "ENTYVIO": 2.7707804589218825, "FASENRA": 4.202968840564676, "FASLODEX": 3.834330821313552, "FIASP": 5.843773635635211, "FORSTEO": 2.101336374302681, "GARDASIL": 0.5710234489476439, "HIZENTRA": 4.793215582644109, "HUMALOG": 1.642063616574098, "INSULATARD": 13.398190512472777, "INSULIN": 1.1743667763140486, "LANTUS": 1.301276761518893, "LEVEMIR": 10.977259587727488, "LEVOFLOXACIN": 0.6643959201283843, "MMRVAXPRO": 4.624084386621269, "MODERNA": 5.540979609357985, "NIMENRIX": 3.5116178554161763, "NOVORAPID": 3.2139389143208463, "NUCALA": 1.2528783075138377, "OCRELIZUMAB": 2.126582014570768, "PEGASYS": 4.488240407203239, "PEGINTERFERON": 1.2784939702911808, "PEGINTRON": 5.529265529774063, "PLEGRIDY": 35.01971771916899, "ROACTEMRA": 8.079275662635757, "SAXENDA": 48.78521392180695, "SHINGRIX": 5.685430685795132, "SIMPONI": 0.6366689464199351, "SPIKEVAX": 2.978325004845822, "STELARA": 1.020406346222645, "TREMFYA": 2.190408239490503, "TRULICITY": 16.084646214496072, "VAXZEVRIA": 0.8615110826798812, "VICTOZA": 12.192749550978744, "XOLAIR": 2.0114252623578666, "ZOSTAVAX": 2.7632882707851008, "null": 0.4623206157808408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6404.json
index 291147f03b4..c21b00c906c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6404.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6404.json
@@ -1 +1 @@
-{"BORTEZOMIB": 202.4132823908067, "CARFILZOMIB": 126.26456772180592, "DARZALEX": 54.03659493762508, "DEXAMETHASONE": 32.8993387242471, "REVLIMID": 107.8712812442313}
\ No newline at end of file
+{"ABASAGLAR": 2.407472071824382, "ABATACEPT": 0.5945303416671504, "ACTRAPID": 1.0426736673434664, "ADALIMUMAB": 1.555843892942714, "AIMOVIG": 1.6054737350888952, "ANAKINRA": 2.632589916987689, "APIDRA": 1.3631108965173158, "ARANESP": 0.2279039875273965, "ARAVA": 0.9796059710346856, "AVAMYS": 0.2465087890175525, "AZATHIOPRINE": 0.4589933643102492, "BENLYSTA": 0.3938974119052688, "BETAFERON": 11.620657051754536, "BEXSERO": 1.1534767951195608, "BONVIVA": 1.675489619862352, "BUVIDAL": 3.042190760083189, "BYDUREON": 1.2535068363716972, "CABOTEGRAVIR": 4.015109574368509, "CIMZIA": 1.8987405507039563, "COMIRNATY": 2.743975432465247, "COSENTYX": 1.1507855282532822, "ENBREL": 2.5244079279319647, "ENOXAPARIN": 0.9239907156232592, "ENTYVIO": 2.754733356731633, "EVENITY": 1.1634485995246042, "FASENRA": 1.5305527879192689, "FASLODEX": 1.2915108175860035, "FIASP": 1.143829384482062, "FORSTEO": 0.5564082488697846, "GARDASIL": 0.6105758250502645, "HEMLIBRA": 2.481843720567228, "HIZENTRA": 1.3948580130964423, "HUMALOG": 0.4134988876240816, "HUMIRA": 0.4382849837281469, "IDACIO": 4.517619077376616, "INFANRIX": 1.840121132372016, "INSULATARD": 3.773379391242388, "INSULIN": 0.9368600436835473, "KESIMPTA": 1.926540528830172, "LANTUS": 0.9615676690932716, "LEVEMIR": 4.113885536368621, "LYUMJEV": 6.199753713454663, "MENVEO": 2.547688211026684, "METHOTREXATE": 0.3958729484935918, "MIXTARD": 5.044178056233551, "MMRVAXPRO": 0.4746881175266585, "MODERNA": 0.6725374038810361, "NEULASTA": 0.4664841104986847, "NIMENRIX": 1.877127864737281, "NOVORAPID": 0.6498568844612147, "NUCALA": 0.3059640758905482, "OMALIZUMAB": 0.7684336503094691, "PEGASYS": 1.3720175115462756, "PEGINTERFERON": 0.7028692984411139, "PEGINTRON": 2.814292652181166, "PLEGRIDY": 16.927750627550914, "REBETOL": 1.2640422352805312, "REKAMBYS": 6.399790897747688, "ROACTEMRA": 4.806494682969876, "SAXENDA": 2.829861355947425, "SHINGRIX": 1.1491580737545857, "SIMPONI": 0.5358349039599135, "SPIKEVAX": 4.053459073078722, "STELARA": 0.6531178237156091, "TOUJEO": 0.5492677475206446, "TREMFYA": 3.076832067767031, "TRULICITY": 3.0564400439672155, "TWINRIX": 1.2399572719286718, "VAXZEVRIA": 2.085349500380978, "VICTOZA": 1.6142741609840607, "XOLAIR": 2.1324345902204658, "ZOSTAVAX": 0.5433438769551329, "null": 0.2689763154580477}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6405.json
index 4c43a2fffc4..380f1bbf119 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6405.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6405.json
@@ -1 +1 @@
-{"ARANESP": 1.082585355030399, "BELANTAMAB": 81.30944715832501, "BORTEZOMIB": 123.95715837787353, "CAELYX": 6.550785786912292, "CARFILZOMIB": 250.1091458598949, "CARMUSTINE": 2.309216098104557, "CELLCEPT": 1.0106774593882086, "DARATUMUMAB": 110.3570070557018, "DARZALEX": 131.17081336307456, "DEXAMETHASONE": 32.54864684551133, "EMPLICITI": 115.28354830433628, "EVENITY": 1.391900026165089, "FILGRASTIM": 2.186982839596736, "FORSTEO": 2.533891197232653, "IMNOVID": 88.85475027703849, "ISATUXIMAB": 120.19680629071564, "KYPROLIS": 62.7449831745164, "LENALIDOMIDE": 15.03797815831158, "MELPHALAN": 17.811635782609535, "NINLARO": 101.63486272063848, "NPLATE": 3.043583585862543, "POMALIDOMIDE": 168.79004554642137, "REVLIMID": 112.17963108683212, "STELARA": 1.0267813801260917, "THALIDOMIDE": 49.61178118538482, "VELCADE": 42.29686851612029, "VENETOCLAX": 11.670601936418954, "null": 1.9081064501385383}
\ No newline at end of file
+{"BYDUREON": 36.18344023218586, "null": 0.3476664059591997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6406.json
index 18af5ebf487..7ca01b0cf22 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6406.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6406.json
@@ -1 +1 @@
-{"BORTEZOMIB": 184.7513470758042, "CAELYX": 21.28066622512318, "CARFILZOMIB": 310.350688266078, "DARATUMUMAB": 136.46929935798, "DARZALEX": 84.71844872614702, "DEXAMETHASONE": 65.36531828380281, "KYPROLIS": 81.70648494324013, "NINLARO": 99.10039417222528, "POMALIDOMIDE": 93.22531068431744, "REVLIMID": 118.28309937211156, "THALIDOMIDE": 46.55714078620445}
\ No newline at end of file
+{"BYDUREON": 26.10820811220562, "HUMALOG": 13.947036794018963, "LANTUS": 7.296281495093635, "VAXZEVRIA": 0.2654005299319645, "null": 1.359499997615784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6407.json
index 570f3cd9bf7..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6407.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6407.json
@@ -1 +1 @@
-{"BORTEZOMIB": 690.6130652070248, "CARFILZOMIB": 656.2514909092383, "DARZALEX": 50.34665769884432, "DEXAMETHASONE": 125.20869105062272}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6408.json
index fdffa6dd24c..e79ae0cf363 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6408.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6408.json
@@ -1 +1 @@
-{"null": 1.7203581838430817}
\ No newline at end of file
+{"ABASAGLAR": 0.7472065325027363, "ADALIMUMAB": 0.0103175707021023, "AIMOVIG": 1.164914801657078, "APIDRA": 0.2620882946949803, "BENLYSTA": 0.1042282961158048, "BETAFERON": 1.4044462138712932, "BEXSERO": 1.071251503769685, "BONVIVA": 1.1106779892748746, "BRINTELLIX": 2.1798499880684754, "BUVIDAL": 8.387197302836425, "BYDUREON": 0.997941510941652, "BYETTA": 0.0974321213769711, "CABOTEGRAVIR": 2.1918420339120623, "CERVARIX": 2.458172360727372, "CIMZIA": 0.5116187172955251, "COMIRNATY": 3.238765815235214, "COSENTYX": 0.327857286316045, "DEXAMETHASONE": 0.0483692920981419, "ENBREL": 0.4407748275497333, "ENOXAPARIN": 0.204492992511464, "ENTYVIO": 0.880489334904948, "EVENITY": 2.986074547492431, "FASENRA": 0.3231212207171341, "FASLODEX": 0.6171497505288491, "FIASP": 0.5580591274697063, "FORSTEO": 0.2876366576981751, "GARDASIL": 0.5830178934875095, "HEMLIBRA": 0.6502050389063454, "HIZENTRA": 2.4282649304612463, "HUMALOG": 0.186023912803562, "HUMIRA": 0.0994536998538764, "HYQVIA": 1.7036059319496797, "INFANRIX": 1.4217000954586525, "INSULATARD": 0.9118737890049328, "INSULIN": 0.202969538577726, "JCOVDEN": 2.1078862232316267, "KESIMPTA": 1.0468172590494114, "LANTUS": 0.2437102301546016, "LEVEMIR": 2.0638173664893213, "LYUMJEV": 1.6961561025036835, "MENQUADFI": 6.5697580854623325, "MENVEO": 1.6460085445460495, "MEPOLIZUMAB": 1.0325063028763797, "MIXTARD": 1.1304328600054914, "MMRVAXPRO": 2.586641463528682, "MODERNA": 0.1342048765119133, "NIMENRIX": 7.183105379387489, "NOVORAPID": 0.2341249536852939, "NUCALA": 0.297191165240152, "OCRELIZUMAB": 0.1464544017535883, "OCTREOTIDE": 1.9628528606252589, "OMALIZUMAB": 0.4986651383256665, "PEGASYS": 0.0676653945180361, "PEGINTRON": 0.1382652604983438, "PLEGRIDY": 1.9695458877910617, "REKAMBYS": 3.4304522456163618, "ROACTEMRA": 0.6439481592254814, "SAXENDA": 2.678936252607946, "SHINGRIX": 3.575588906173622, "SIMPONI": 0.0816381485737372, "SPIKEVAX": 9.29302841216401, "STELARA": 0.1585081820959475, "SYNAGIS": 0.2559858576753517, "TOUJEO": 0.4408339171393408, "TOZINAMERAN": 0.0151137679799084, "TREMFYA": 0.6585043225521445, "TRULICITY": 1.7143887338002877, "TWINRIX": 1.9806631401748132, "VAXZEVRIA": 1.888193759430652, "VICTOZA": 0.4608559514549888, "XOLAIR": 0.8004588668378014, "ZOSTAVAX": 0.6134079182285018, "ZYPADHERA": 0.2536258940570184, "null": 0.1400621059134885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6409.json
index 5338f57a69c..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6409.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6409.json
@@ -1 +1 @@
-{"ADALIMUMAB": 4.401785795732926, "CICLOSPORIN": 27.7436503463608, "COMBIVIR": 71.219658842243}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/641.json
index a7ac4f740ce..731a739207a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/641.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/641.json
@@ -1 +1 @@
-{"null": 1.186077944205506}
\ No newline at end of file
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6410.json
index 73084a23e4c..9030468c470 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6410.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6410.json
@@ -1 +1 @@
-{"BORTEZOMIB": 139.77245146240406, "CARFILZOMIB": 185.76647810811983, "CICLOSPORIN": 8.278193627554993, "DARZALEX": 76.77781212474392, "DEXAMETHASONE": 31.2116566885422, "FORSTEO": 4.2327796081995, "KYPROLIS": 100.71757198604698, "POMALIDOMIDE": 119.62528421273352, "REVLIMID": 116.41884360165386, "THALIDOMIDE": 74.41602336223518}
\ No newline at end of file
+{"null": 5.543588604028688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6411.json
index cebf1376265..372dfa8a0ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6411.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6411.json
@@ -1 +1 @@
-{"null": 1.3075545298535065}
\ No newline at end of file
+{"ACTRAPID": 72.07452070892896, "BETAFERON": 150.39654939070428, "FASLODEX": 62.724824249174034, "HIZENTRA": 19.712268372051007, "LAMIVUDINE": 37.96669611181628, "LANTUS": 2.684951090862003, "PEGASYS": 2.5739437988065528, "PEGINTRON": 54.40757624041827, "null": 0.8483160152276764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6412.json
index 595ec4af79d..53f7c00ca3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6412.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6412.json
@@ -1 +1 @@
-{"SOLIRIS": 44.02007672414733}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6413.json
index c284d18f11b..270ff284b58 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6413.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6413.json
@@ -1 +1 @@
-{"null": 2.321372237564148}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6414.json
index abd9c33c0b4..e3bbd16a4eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6414.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6414.json
@@ -1 +1 @@
-{"null": 2.158702033383775}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6415.json
index 2d6d7955cba..d845f315df1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6415.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6415.json
@@ -1 +1 @@
-{"null": 1.3745155205357629}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6416.json
index 04f83c0802b..ece9d78d57b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6416.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6416.json
@@ -1 +1 @@
-{"null": 2.119843710264686}
\ No newline at end of file
+{"ABASAGLAR": 22.5503474954124, "AIMOVIG": 2.90133163031087, "BYDUREON": 4.6591848492103205, "FORSTEO": 6.15273551830467, "HUMALOG": 14.483191720946513, "INSULIN": 7.988120154026569, "LANTUS": 11.232996585754025, "PLEGRIDY": 55.38351522912368, "ROACTEMRA": 6.304676942422692, "SIMPONI": 21.922447580414573, "STELARA": 1.609726226730158, "TRULICITY": 8.359553808840856, "VAXZEVRIA": 0.0737714402355533, "null": 1.832528925373856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6417.json
index 20020f8a1a6..4450f01ff1f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6417.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6417.json
@@ -1 +1 @@
-{"null": 1.115179498463266}
\ No newline at end of file
+{"null": 1.402937741052847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6418.json
index bac390078e8..5066fda4708 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6418.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6418.json
@@ -1 +1 @@
-{"TICAGRELOR": 471.91629779597486, "null": 1.1733358945517447}
\ No newline at end of file
+{"COMIRNATY": 1.1409715987668074, "SPIKEVAX": 0.4614494241778238, "TOZINAMERAN": 1.713352772921621, "VAXZEVRIA": 0.5207766185692556, "null": 0.7857322092059679}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6419.json
index 9c7322d56ba..a422c26478f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6419.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6419.json
@@ -1 +1 @@
-{"ADENURIC": 17.25268611390025, "ARANESP": 3.3385415789168094, "CYTARABINE": 3.861330290451181, "IBRANCE": 1.2314648088425837, "ICLUSIG": 9.54351824708954, "JAKAVI": 15.920147433236416, "KEYTRUDA": 1.8338824929256452, "LEMTRADA": 17.11617574383416, "LENALIDOMIDE": 51.36176312677823, "NEULASTA": 8.719795505914457, "NPLATE": 460.8840840660201, "PEGASYS": 4.764929184154894, "PEGINTRON": 1.2814586029400237, "RUXOLITINIB": 41.54108764443495, "SOLIRIS": 21.21316660301365, "SUTENT": 1.3995841295711453}
\ No newline at end of file
+{"COMIRNATY": 0.9996041367842974, "SPIKEVAX": 2.502296931125042, "TOZINAMERAN": 4.789884614723969, "null": 0.236432641128267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/642.json
index 10ade746ec7..b1dd1e762fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/642.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/642.json
@@ -1 +1 @@
-{"null": 8.782520890325227}
\ No newline at end of file
+{"SPIKEVAX": 2.1608260134199724, "null": 0.979572353271942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6420.json
index 0034310930e..222bf85aebe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6420.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6420.json
@@ -1 +1 @@
-{"ABEMACICLIB": 5.768634076520544, "ABRAXANE": 1.9044746010383005, "ADCETRIS": 1.0914173221910917, "ADCIRCA": 3.2246804373193183, "ADENURIC": 1.0658392773346486, "AFINITOR": 3.4092589138839258, "ALIMTA": 5.816457706133234, "AMINOSALICYLIC": 1.04556225301418, "ANAGRELIDE": 6.713019868553475, "ANGIOX": 2.9170750797567284, "ARIPIPRAZOLE": 1.3373400362231076, "ASPARAGINASE": 1.004607946373662, "ATEZOLIZUMAB": 1.2465845124422432, "AVASTIN": 4.61056391993668, "AXICABTAGENE": 2.123433829948547, "AZACITIDINE": 5.2840529728928205, "AZATHIOPRINE": 1.2689883856305109, "BARACLUDE": 1.676794687114764, "BARICITINIB": 29.991794752000008, "BAVENCIO": 1.1015343427343212, "BEDAQUILINE": 2.255987249836561, "BELANTAMAB": 9.395397853734124, "BELIMUMAB": 1.3129071931195095, "BEVACIZUMAB": 3.52797003831426, "BLINCYTO": 5.596612474194603, "BLINDED": 9.64128768973362, "BOCEPREVIR": 2.4932417112616867, "BORTEZOMIB": 2.2168492408265026, "BOSULIF": 2.1146898451377094, "BREYANZI": 8.313159966355384, "BRUKINSA": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6421.json
index 2764c2a63d9..d843d6cc544 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6421.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6421.json
@@ -1 +1 @@
-{"ABATACEPT": 1.3250321774535765, "AFINITOR": 2.567058554965121, "ALIMTA": 1.714003921172142, "AMINOSALICYLIC": 6.496394947453721, "ANAGRELIDE": 70.73577353593751, "BEDAQUILINE": 20.88064800573933, "BOSULIF": 8.311839426802559, "BRILIQUE": 1.8130853715512576, "BUDESONIDE": 20.795334418912905, "BUSILVEX": 17.440617916739587, "CICLOSPORIN": 1.991014630480584, "CLOPIDOGREL": 2.342417069614416, "CYTARABINE": 2.2922483742357858, "DACLATASVIR": 10.086642594741278, "DEXAMETHASONE": 1.5190543219690271, "ENTYVIO": 2.3382265826720823, "EXJADE": 4.981653757931294, "FULVESTRANT": 2.1715958955811145, "GLIVEC": 4.857422139270834, "HUMIRA": 1.6993360210453532, "HYDROXYCARBAMIDE": 58.28767027844895, "IBRANCE": 1.1220300293592191, "JAKAVI": 55.85902523398672, "LEMTRADA": 1.7465509457834172, "MEKINIST": 1.9977597104089373, "NEXAVAR": 1.152353338405364, "NPLATE": 57.43959250496793, "NUCALA": 21.700830133042984, "PANTOPRAZOLE": 3.0373225541014124, "PEGASYS": 1.180561357360045, "RINVOQ": 4.8985689135926105, "RUXOLITINIB": 25.26832647194433, "SOLIRIS": 3.206291831953534, "SPRYCEL": 3.0776449567349133, "SUTENT": 1.0275915718638966, "TASIGNA": 4.554988105601887, "XELJANZ": 1.042165317494412, "ZYPREXA": 1.9708852780372712}
\ No newline at end of file
+{"TICAGRELOR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6422.json
index 5f7ea0f3c2e..1edab83b5b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6422.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6422.json
@@ -1 +1 @@
-{"SPIKEVAX": 13.620252842493365}
\ No newline at end of file
+{"BUDESONIDE": 79.46862170332938, "FENTANYL": 193.36732750027576, "null": 0.3461473379860954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6423.json
index e935647fcce..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6423.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6423.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 2.004966686174166, "DEXAMETHASONE": 3.2083217914490456, "IBRANCE": 3.723636835827567, "JAKAVI": 7.057734453232928, "LENALIDOMIDE": 160.24766203663197, "NPLATE": 28.565846645997446, "PEGASYS": 4.254657659778611, "RITUXIMAB": 5.046152382377004, "SUTENT": 2.532136574134029, "null": 1.002492638258273}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6424.json
index 7777fd2a2bb..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6424.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6424.json
@@ -1 +1 @@
-{"PLAVIX": 51.65079099407865, "null": 1.3163797674030808}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6425.json
index 29240e66865..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6425.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6425.json
@@ -1 +1 @@
-{"ADCIRCA": 63.65494520700914, "ELIQUIS": 2.6949095395854026, "OPSUMIT": 26.24741529965362, "SOLIRIS": 10.450685731660364, "SPRYCEL": 16.00890211337492, "TEMODAL": 56.87757181459276, "TEMOZOLOMIDE": 80.54199615150993, "TRACLEER": 11.800070091411234}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6426.json
index 9ec5b064a97..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6426.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6426.json
@@ -1 +1 @@
-{"CICLOSPORIN": 7.051373543851954, "DARUNAVIR": 76.14576800980407, "DEXAMETHASONE": 17.672185714803042, "SPINRAZA": 61.1953986922888}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6427.json
index d12fc060f5d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6427.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6427.json
@@ -1 +1 @@
-{"ANAKINRA": 88.2559498903586, "SOMATROPIN": 349.2422085660759}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6428.json
index 7df5251a0d1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6428.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6428.json
@@ -1 +1 @@
-{"ABRAXANE": 8.437691917801445, "ACLASTA": 4.006768957930272, "ACTOS": 2.096929839241975, "ACTRAPID": 1.1578672067999407, "ADEMPAS": 1.3276031952166745, "ADENURIC": 1.485057478781899, "AERIUS": 1.015861541660028, "AFINITOR": 5.85024531693692, "ALEMTUZUMAB": 1.0546000560667923, "ALIMTA": 5.273227639183809, "ARANESP": 1.0582967735304727, "ASPARAGINASE": 1.4075345818646905, "AVAMYS": 1.0786972232320104, "AVANDAMET": 5.824423803126988, "AVANDIA": 7.120059347451, "AVASTIN": 1.4768741614514769, "AXITINIB": 1.8652082321016583, "BASILIXIMAB": 5.060201675862896, "BENLYSTA": 1.1301680776481666, "BEVACIZUMAB": 2.018593796112311, "BLINCYTO": 4.258181333604145, "BORTEZOMIB": 1.8542920741510611, "BOSULIF": 25.190130504144733, "BOSUTINIB": 34.44009112692088, "BUDESONIDE": 2.1121270573677804, "BUSULFAN": 2.5422128560813952, "BYETTA": 1.2559929099423466, "CABOMETYX": 2.4287924215629757, "CAELYX": 1.384285836811694, "CAPECITABINE": 1.1814552004752907, "CARFILZOMIB": 3.834160665216909, "CARMUSTINE": 1.660207810906613, "CASPOFUNGIN": 1.7256874653803045, "CELLCEPT": 2.033584905738471, "CETROTIDE": 5.7916252601346, "CICLOSPORIN": 2.0851520573548767, "CLADRIBINE": 1.683012612497442, "COMTAN": 1.4346054162114992, "COTELLIC": 1.283683942817699, "CRIXIVAN": 1.0503446588930376, "CRIZOTINIB": 5.458902812646247, "CUBICIN": 2.292014885393016, "CYTARABINE": 3.425071193535427, "DARATUMUMAB": 2.800230079589462, "DARZALEX": 1.4089906521217237, "DASATINIB": 23.185611889913705, "DENOSUMAB": 3.3941981078152272, "DEXAMETHASONE": 1.6005564900369709, "DOCETAXEL": 3.3059096040541758, "DOLUTEGRAVIR": 1.8167260549453128, "DOXORUBICIN": 2.4779199941933907, "ELIQUIS": 1.2410511282221537, "EMEND": 1.6550889701317406, "ENTRESTO": 1.44922624538855, "ENVARSUS": 13.451571400694606, "EPADERM": 34.517328009414946, "EPCLUSA": 1.3387949693838057, "ERIBULIN": 8.976950703173097, "ESOMEPRAZOLE": 3.36544633749827, "EVEROLIMUS": 2.9858586237120983, "EVISTA": 1.0602821614834232, "EXJADE": 1.7255252373413508, "EXVIERA": 1.0279678471100566, "FASLODEX": 4.804916245286972, "FILGRASTIM": 2.5036895903331797, "FIRDAPSE": 1.9629697715822436, "FOTIVDA": 4.489202604559692, "FULVESTRANT": 4.109089641700626, "GAZYVARO": 1.2881292617067297, "GEFITINIB": 7.3092818920871, "GLIVEC": 9.489629644111986, "GONALF": 16.71601558581784, "HALAVEN": 3.786833643269671, "HARVONI": 1.00722910361784, "HERCEPTIN": 3.846065370159309, "HYCAMTIN": 1.4920580309982825, "IBRANCE": 3.164173986143324, "ICLUSIG": 5.522035925912177, "ILARIS": 4.069871945152817, "IMATINIB": 3.405736471819357, "IMBRUVICA": 4.370311145612399, "INFLIXIMAB": 1.99938324073977, "INLYTA": 1.685360258635232, "INTEGRILIN": 2.7330007152868947, "INTRONA": 2.73668783993894, "IPILIMUMAB": 1.4702687812669446, "IRESSA": 8.540891072572432, "IRINOTECAN": 1.384531870304463, "JAKAVI": 2.266021602565759, "JANUMET": 1.455995013324789, "JANUVIA": 1.59118519661312, "JEVTANA": 2.191063587946617, "KEYTRUDA": 3.7989200562171, "KISQALI": 3.0428501860148667, "KYMRIAH": 2.065617109154086, "KYPROLIS": 2.3427551917676555, "LEFLUNOMIDE": 1.0977343870556553, "LENVIMA": 2.925435608422407, "LEVOFLOXACIN": 1.0518038548125055, "LYNPARZA": 1.898914819922242, "MABCAMPATH": 5.514504790889189, "MACITENTAN": 2.7701980531758794, "MEKINIST": 1.4488175130380656, "MELPHALAN": 3.263682816630683, "MERCAPTOPURINE": 1.458224988815807, "MICARDIS": 1.0201986902215252, "MULTAQ": 2.12957804766806, "MYCOPHENOLATE": 1.2394153592349135, "NEULASTA": 1.6404685301055322, "NEXAVAR": 1.9220196576473576, "NILOTINIB": 7.70811254900449, "NINLARO": 1.387379562788904, "NITRIC": 19.000574397200637, "NOXAFIL": 1.3306147223080678, "NPLATE": 4.769703720102466, "OFEV": 1.069885996572143, "ONCASPAR": 1.9422463059798865, "OPDIVO": 2.898203566072025, "OPSUMIT": 3.447341206646472, "ORGALUTRAN": 9.870513781926528, "OSIMERTINIB": 6.853987656099673, "OVITRELLE": 12.057259500379256, "PACLITAXEL": 2.119235437801376, "PAZOPANIB": 3.8665750483282393, "PEMBROLIZUMAB": 2.375550063168703, "PEMETREXED": 2.607980512916922, "PRADAXA": 2.0913078488472983, "RAPAMUNE": 2.033187845704041, "REBETOL": 1.7164699670033283, "REVATIO": 2.076108301167222, "REVLIMID": 1.582083394160705, "RIBOCICLIB": 4.336217119998718, "RITUXIMAB": 1.4898465050664935, "ROACTEMRA": 1.08976973000277, "RUBRACA": 2.036136003862858, "RUXOLITINIB": 2.365438966547613, "SAMSCA": 5.187733378137275, "SILDENAFIL": 1.7482123986709956, "SOLIRIS": 1.7535669150326134, "SORAFENIB": 1.691030682324599, "SPIRONOLACTONE": 1.4984473880578828, "SPRYCEL": 109.2133794519122, "STIVARGA": 1.5528161189511749, "SUTENT": 3.764100273041752, "TACROLIMUS": 1.1876547209039197, "TAGRISSO": 10.054866459723204, "TASIGNA": 7.861704993037496, "TAXOTERE": 2.617807302711724, "THALIDOMIDE": 1.198334201488159, "TOPOTECAN": 1.473473901293939, "TORISEL": 9.44131382555991, "TRACLEER": 3.2224525026407527, "TRACTOCILE": 10.504424069460146, "TRISENOX": 5.044322757776238, "TRODELVY": 1.7155786991362163, "VALSARTAN": 1.0248564204941724, "VENCLYXTO": 1.9820892033532465, "VENETOCLAX": 2.65605544225935, "VFEND": 1.1280945202006083, "VOTRIENT": 3.7955905366705656, "XALKORI": 8.049614158492712, "XOFIGO": 1.5802844987144553, "XTANDI": 1.003207415369498, "YERVOY": 2.1793372659633947, "YESCARTA": 2.4143088169479467, "YONDELIS": 3.156311965447801}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6429.json
index 98b2905b44a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6429.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6429.json
@@ -1 +1 @@
-{"ABATACEPT": 22.850581039941893, "ARAVA": 5.866102604500076, "ENBREL": 17.93538475976761, "null": 1.2732112529018609}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/643.json
index aae74a0243f..d8ff5fb4e76 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/643.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/643.json
@@ -1 +1 @@
-{"null": 1.1754565013842662}
\ No newline at end of file
+{"null": 0.607446179040787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6430.json
index 1ecbb7294af..ab23b22acfd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6430.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6430.json
@@ -1 +1 @@
-{"XOLAIR": 121.40023571606756}
\ No newline at end of file
+{"null": 4.951566125954974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6431.json
index 8954deef6c3..c440f5cc6e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6431.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6431.json
@@ -1 +1 @@
-{"ABATACEPT": 11.486349846877108, "AFINITOR": 6.412706273956337, "ARAVA": 4.670280547142492}
\ No newline at end of file
+{"null": 3.51233967253537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6432.json
index 34946e8c720..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6432.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6432.json
@@ -1 +1 @@
-{"AMIKACIN": 6.735529907934369, "BEDAQUILINE": 6.258773779897765, "BENLYSTA": 8.128558707938724, "CELLCEPT": 1.2799725616264082, "CIMZIA": 1.112042715437852, "HUMIRA": 1.681956735294511, "KEYTRUDA": 1.9701407143177947, "METHOTREXATE": 3.2416719343756286, "NEXAVAR": 2.0141032359866107, "PEGASYS": 2.493331852741769, "PEGINTRON": 2.2881452715823616, "ROACTEMRA": 1.69676574700422, "SIMPONI": 3.828720880812159, "SPRYCEL": 14.555241378223528, "STELARA": 1.8426969070797805, "TASIGNA": 2.5530031025859348, "XELJANZ": 1.4197686438426096, "XOLAIR": 1.5797609590171993, "null": 1.0687558004056457}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6433.json
index ec07d5eb4aa..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6433.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6433.json
@@ -1 +1 @@
-{"ASPARAGINASE": 4.9786162063403, "AZATHIOPRINE": 4.999005142093742, "BUDESONIDE": 24.903057756599843, "CHAMPIX": 1.294487770199927, "CICLOSPORIN": 1.139748794147006, "COMIRNATY": 1.0063650589010296, "NUCALA": 3.8535175399403543, "PANTOPRAZOLE": 13.008268417714902, "SPIKEVAX": 1.2489809780915757, "SUTENT": 1.6809305295315675, "TOZINAMERAN": 2.9537116144952367}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6434.json
index 2b6d2342382..c55fa55abc6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6434.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6434.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7422912471081762, "SPIKEVAX": 1.2103926583973674}
\ No newline at end of file
+{"ONCASPAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6435.json
index b914c766e01..761c2246b18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6435.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6435.json
@@ -1 +1 @@
-{"ABILIFY": 11.008924038585253, "OLANZAPINE": 69.58405259296852, "ZYPREXA": 13.29450809415053, "null": 1.9845992777308743}
\ No newline at end of file
+{"ORENCIA": 5460.864244745746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6436.json
index 72bb7a9d958..bcd37a4b969 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6436.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6436.json
@@ -1 +1 @@
-{"MIRABEGRON": 426.50703372673775}
\ No newline at end of file
+{"null": 4.466202627667591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6437.json
index 3d70e9ec177..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6437.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6437.json
@@ -1 +1 @@
-{"LEVETIRACETAM": 36.04375776367828}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6438.json
index 7446f1144bf..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6438.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6438.json
@@ -1 +1 @@
-{"ASPARAGINASE": 113.87109256001396, "AVASTIN": 6.979874937005742, "BUSULFAN": 7.57745351509045, "CABOMETYX": 9.93382171689049, "CELLCEPT": 3.451755876689333, "CICLOSPORIN": 9.067916952336407, "CYTARABINE": 16.22595817284289, "DOCETAXEL": 5.056969776330204, "IRESSA": 22.450609301793232, "KEYTRUDA": 3.6030559072700488, "LENVIMA": 12.528553601031517, "METHOTREXATE": 2.767444045561092, "NEXAVAR": 4.561519399465767, "SUTENT": 2.0832170272996344, "null": 1.102325332911981}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6439.json
index f3fb470b4d4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6439.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6439.json
@@ -1 +1 @@
-{"BYETTA": 96.8829292325847, "JANUMET": 171.5832851999647, "JANUVIA": 67.64771204508088}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/644.json
index 96941c56c9c..3a9d0cf08cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/644.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/644.json
@@ -1 +1 @@
-{"null": 17.88498050344945}
\ No newline at end of file
+{"null": 2.118328606160788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6440.json
index 7745803e8ba..b30067de1a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6440.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6440.json
@@ -1 +1 @@
-{"null": 3.7069770407614007}
\ No newline at end of file
+{"null": 1.5854742411385632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6441.json
index f8fded99010..3a9d0cf08cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6441.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6441.json
@@ -1 +1 @@
-{"CELLCEPT": 14.769015900121117, "PEGASYS": 3.7472211405682647}
\ No newline at end of file
+{"null": 2.118328606160788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6442.json
index 5401776b47f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6442.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6442.json
@@ -1 +1 @@
-{"null": 3.913732912441447}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6443.json
index 1010edc7a0b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6443.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6443.json
@@ -1 +1 @@
-{"ABACAVIR": 7.609767410855049, "CASPOFUNGIN": 53.62121961048446, "CELLCEPT": 22.760208417529224, "CICLOSPORIN": 10.4268682501703, "CYTARABINE": 14.945647142137853, "TEMODAL": 55.0193527045579}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6444.json
index 3049c3d1369..49893e3acf0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6444.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6444.json
@@ -1 +1 @@
-{"ABACAVIR": 1.3495821354321105, "ACTRAPID": 11.995337305180469, "ADCETRIS": 36.70440870977886, "AFINITOR": 6.639894025005895, "ALEMTUZUMAB": 10.72556943342062, "ALIMTA": 1.3836629391087565, "ASPARAGINASE": 2.80990899806932, "ATAZANAVIR": 3.2423914012172053, "AVASTIN": 1.117193478284909, "AZACITIDINE": 4.810503632835713, "AZATHIOPRINE": 4.925131245361223, "BASILIXIMAB": 29.856816599360705, "BENLYSTA": 1.421154286092055, "BEVACIZUMAB": 3.234417694715552, "BIKTARVY": 6.084671348336378, "BLINCYTO": 36.114422173161934, "BUSULFAN": 8.031047056597318, "CARMUSTINE": 20.318614157098374, "CELLCEPT": 17.860818541303043, "CICLOSPORIN": 8.921894943169129, "CIMZIA": 1.0981540245963977, "COMBIVIR": 4.627442006135585, "CYTARABINE": 4.394982201765128, "DARATUMUMAB": 34.459013345949, "DARUNAVIR": 26.9502989311732, "DARZALEX": 3.164763672908086, "DESCOVY": 10.607492205056912, "DEXAMETHASONE": 8.15847604581049, "DOCETAXEL": 2.5702896223938048, "DOXORUBICIN": 16.595479193898992, "EMTRICITABINE": 8.01648309077969, "EPIVIR": 9.083205861262153, "GANCICLOVIR": 17.951250688834016, "HALAVEN": 4.413919403031031, "HERCEPTIN": 2.172956973179268, "HUMIRA": 1.0205735737895476, "INFLIXIMAB": 4.5489797844148745, "IPILIMUMAB": 2.082410976904716, "IRESSA": 1.855735911667845, "ISENTRESS": 9.502252732514217, "JAKAVI": 5.176793968060559, "KALETRA": 4.44212250808757, "KEYTRUDA": 4.056222237555544, "LAMIVUDINE": 4.145989802783515, "LEVOFLOXACIN": 2.092981062109333, "LYNPARZA": 3.963258387920126, "MABTHERA": 44.47282078568343, "MERCAPTOPURINE": 5.673383651283134, "METHOTREXATE": 13.386135596273306, "MYCOPHENOLATE": 13.072287889091877, "OPDIVO": 3.897909439326853, "PEMBROLIZUMAB": 2.3491300736374656, "RAPAMUNE": 7.117993153674562, "REMICADE": 12.640648091353777, "RINVOQ": 9.514856509044794, "RITUXIMAB": 33.200442139688704, "ROACTEMRA": 4.3530857004683705, "SIMPONI": 7.1081865439948215, "TAGRISSO": 2.552700740824178, "TEMODAL": 30.5036585333217, "TEMOZOLOMIDE": 17.669069548919932, "TIVICAY": 7.291528400449626, "TORISEL": 23.487759819321926, "XELJANZ": 1.5135124536119404, "ZIAGEN": 10.561805036617551}
\ No newline at end of file
+{"null": 1.3435687771524831}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6445.json
index e4b2b98c8f2..ef6962f7396 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6445.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6445.json
@@ -1 +1 @@
-{"BIKTARVY": 19.300673001841798, "CICLOSPORIN": 9.7615020212804, "COSENTYX": 5.403606201727981, "DEXAMETHASONE": 13.122434125717852, "FENTANYL": 4.810580710742442, "OFEV": 12.962014744564977, "null": 1.1169586629506216}
\ No newline at end of file
+{"VAXZEVRIA": 3.679109797020926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6446.json
index b89f67c48a7..174ec537647 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6446.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6446.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 49.00196345517049, "TRELEGY": 99.3643285834608, "null": 1.904773272521493}
\ No newline at end of file
+{"HUMALOG": 30.74409091099713, "INSULIN": 47.0142460643323, "JARDIANCE": 30.527523031532443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6447.json
index 0ce076d3623..0e91548326f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6447.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6447.json
@@ -1 +1 @@
-{"ABRAXANE": 1.5590106865518534, "ACLIDINIUM": 4.887498549939374, "ACTOS": 1.0521306713962868, "ADCETRIS": 2.0239026324312097, "ADCIRCA": 1.698857552953501, "ADEMPAS": 1.9206110088508304, "AFINITOR": 2.4807119872560977, "AFLIBERCEPT": 1.0029427327644809, "ALEMTUZUMAB": 1.1840656929539397, "ALIMTA": 1.8705082750012827, "ALL": 1.0865879308528157, "AMBRISENTAN": 1.6189208796578758, "AMIKACIN": 1.5964002973995797, "ANIDULAFUNGIN": 1.0314344443041188, "ANORO": 3.686074107067511, "ANTIBIOTICS": 2.4517125532394286, "APTIVUS": 3.698393232766496, "ARZERRA": 4.458591296339398, "ASPARAGINASE": 1.7756520069005963, "ATEZOLIZUMAB": 1.681655500476296, "AUBAGIO": 1.0450630344901537, "AXICABTAGENE": 1.516447278957577, "AZACITIDINE": 3.904417489215523, "AZATHIOPRINE": 1.0734556340353736, "AZTREONAM": 2.3354444439338824, "BARICITINIB": 14.640098005305184, "BASILIXIMAB": 1.2391393744839971, "BEDAQUILINE": 1.1316131954392934, "BELIMUMAB": 1.39388236141519, "BENLYSTA": 2.927303455571056, "BENRALIZUMAB": 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\ No newline at end of file
+{"INSULIN": 88.02955137683921, "null": 0.8708473976486026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6448.json
index 32773a484e3..20983f25727 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6448.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6448.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 333.0077595131308}
\ No newline at end of file
+{"CLOPIDOGREL": 41.51880028952999, "INSULIN": 56.499012627679946, "LANTUS": 4.587366454375105, "null": 1.642944869548268}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6449.json
index 7c918852423..7c96aa83749 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6449.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6449.json
@@ -1 +1 @@
-{"ABILIFY": 2.252954259495824, "ACIDOPHYLUS": 553.088874749223, "ALIMTA": 1.613463637002595, "ARIPIPRAZOLE": 1.6938583972602128, "BENZODIAZEPINE": 8.895148900799963, "BRAFTOVI": 1.0555530392868568, "BUPIVACAINE": 1.4193616009058678, "BUPRENORPHINE": 1.7155106497586017, "CABOMETYX": 2.0205643439815897, "CARIPRAZINE": 22.40740346294968, "CELLCEPT": 8.844958478506454, "COMTAN": 9.740242249959108, "CYMBALTA": 1.998227481322436, "DARZALEX": 1.7882227178162176, "DULOXETINE": 15.705589249832462, "ELIQUIS": 1.9542569133776773, "ERBITUX": 5.199126358282486, "EVENITY": 5.000132700453898, "FAMPYRA": 1.1013497681437985, "FENTANYL": 1.4719365884489566, "FIRDAPSE": 2.8363868391695477, "FYCOMPA": 5.604614723136496, "INVEGA": 6.268929403487217, "IPILIMUMAB": 1.3374381405825482, "IRESSA": 2.309092362423352, "JAKAVI": 1.4427974026654142, "JANUVIA": 1.2780244295667913, "JARDIANCE": 1.019319201067023, "JEVTANA": 2.280098098708521, "KEPPRA": 2.742012173483117, "KEYTRUDA": 3.5323653893658764, "LACOSAMIDE": 4.601091124815817, "LATUDA": 2.0572458510186435, "LENVIMA": 2.722133455250781, "LEVETIRACETAM": 2.9072903038495497, "LEVOFLOXACIN": 1.0824517971893588, "LIXIANA": 1.4502977484875708, "LYRICA": 3.275018423536069, "MEMANTINE": 7.397405507474271, "MIDAZOLAM": 1.9900064555101955, "NEXAVAR": 1.2079607823395948, "NIVOLUMAB": 8.820163313211008, "OCEAN": 61.49413817699495, "OLANZAPINE": 6.485847307012103, "OPDIVO": 3.1114679618671586, "OPSUMIT": 1.4629495364692744, "OXYBUTYNIN": 4.669580535883602, "PANITUMUMAB": 9.305473080743532, "PERAMPANEL": 20.82629814709234, "PREGABALIN": 3.7271783833101817, "RINVOQ": 1.0909490231738992, "RISPERIDONE": 2.329287172265972, "SPINRAZA": 7.300812164484346, "STALEVO": 8.312145081727648, "SUFENTANIL": 5.033002883227971, "SYCREST": 12.841027614980089, "SYNAGIS": 2.6983985035534634, "TAGRISSO": 2.26254680295525, "TEMODAL": 2.517192178676251, "TRACLEER": 2.1604316075228915, "TRELEGY": 1.063991386753994, "VEKLURY": 18.59509359871149, "VIMPAT": 5.463928137418055, "XTANDI": 2.079228066426385, "ZAVESCA": 17.203773895378895, "ZYPREXA": 5.425633561563041, "null": 1.8917366177057244}
\ No newline at end of file
+{"ACTRAPID": 21.031783213450478, "APIDRA": 9.378273716821695, "BYETTA": 4.568946468936606, "COMIRNATY": 0.1864578593800322, "FIASP": 56.15959659715353, "GARDASIL": 2.472983569635918, "HUMALOG": 57.628252807775496, "INSULIN": 46.7737359422946, "LANTUS": 7.142940633250903, "LEVEMIR": 14.960270792980664, "NOVORAPID": 17.911548066961483, "SOMATROPIN": 35.62490278094377, "SPIKEVAX": 0.1083502648785727, "TOZINAMERAN": 0.2620484772163346, "VAXZEVRIA": 0.1210596886042115, "ZYPREXA": 3.889250128705401, "null": 0.4327906526545766}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/645.json
index 330c8428a59..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/645.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/645.json
@@ -1 +1 @@
-{"CYMBALTA": 5.193343418404978, "null": 1.2175179510255725}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6450.json
index 476862f35bb..76ba5060269 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6450.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6450.json
@@ -1 +1 @@
-{"ADCIRCA": 9.63258671527971, "AFINITOR": 2.5478311057672065, "ALIMTA": 2.7835395416865327, "BASILIXIMAB": 10.052655217649246, "BORTEZOMIB": 8.285454616131386, "BUSULFAN": 4.195578829682562, "CABOMETYX": 3.594198981308985, "CANCIDAS": 6.20480848018251, "CASPOFUNGIN": 8.66790693928, "CELLCEPT": 3.974334792264212, "CICLOSPORIN": 5.559877541838443, "CIMZIA": 1.3694184538236949, "CYTARABINE": 1.59010991488703, "DEXAMETHASONE": 4.1438033194214325, "DOXORUBICIN": 4.575871899759484, "FASENRA": 3.6744238650331686, "GANCICLOVIR": 5.285561322354974, "IRESSA": 10.327780174809508, "JAKAVI": 1.932245873883292, "JEVTANA": 16.179885360866663, "KEYTRUDA": 9.303075547112124, "LEVOFLOXACIN": 1.4994976972028238, "METHOTREXATE": 4.773284246319933, "MICARDIS": 4.173946467813583, "MYCOPHENOLATE": 6.415445726270518, "NUCALA": 2.457264386405713, "OMALIZUMAB": 1.84657758534289, "OPDIVO": 7.333087599237727, "OPSUMIT": 1.497772190733326, "REMDESIVIR": 18.027379736028927, "RINVOQ": 3.905681666530848, "RITUXIMAB": 3.740429481927064, "SIMPONI": 5.376148546687255, "SPINRAZA": 5.863496938056331, "STELARA": 1.2522750611318356, "SYNAGIS": 3.4167918356732008, "TAGRISSO": 8.470957817758496, "TAMIFLU": 6.48537805099744, "TRACLEER": 1.6652281670352764, "TRELEGY": 4.494246955082044, "TREMFYA": 5.5982555188163206, "VEKLURY": 25.596881324023062, "VFEND": 6.087437432974514, "XELJANZ": 2.170113859780184}
\ No newline at end of file
+{"TRULICITY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6451.json
index 89735e605fb..906bb14dbc0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6451.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6451.json
@@ -1 +1 @@
-{"ARAVA": 2.830334034410101, "CELLCEPT": 45.17720101863723}
\ No newline at end of file
+{"HUMALOG": 78.20119097978912}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6452.json
index 6b12bf83a30..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6452.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6452.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 66.76792862072492, "AZATHIOPRINE": 14.63531653190448, "BUSULFAN": 48.776310994085286, "CELLCEPT": 22.29409306475558, "CICLOSPORIN": 33.7268938429351, "CYTARABINE": 11.1639430085824, "DEXAMETHASONE": 5.918473356083501, "GANCICLOVIR": 96.60966432325596, "METHOTREXATE": 4.282878643601265, "MYCOPHENOLATE": 45.275112236602936, "RITUXIMAB": 6.441163796596672, "THIOTEPA": 65.051301155106}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6453.json
index 8296109945d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6453.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6453.json
@@ -1 +1 @@
-{"ASPARAGINASE": 17.05388200448535, "AZACITIDINE": 52.381814793976176, "BUSULFAN": 23.135992557986835, "CARFILZOMIB": 15.855721888869745, "CELLCEPT": 7.279963775959679, "CICLOSPORIN": 9.221449806012398, "CYTARABINE": 24.842092675096893, "DEXAMETHASONE": 7.701276323980196, "GANCICLOVIR": 19.1127906397976, "ICLUSIG": 11.280808610512429, "JAKAVI": 3.0143728405718435, "KYMRIAH": 7.032640355274652, "LEVOFLOXACIN": 3.204626735886338, "MELPHALAN": 27.487919385052948, "METHOTREXATE": 4.121622652731253, "NOXAFIL": 53.83966995819555, "POSACONAZOLE": 48.1700031930461, "RITUXIMAB": 4.613207032307488, "SIMPONI": 1.7652874814539448, "SOLIRIS": 2.917763809911303, "SPRYCEL": 4.469600005136266, "STELARA": 1.3564782458898, "TRELEGY": 4.620909959577586, "VENETOCLAX": 21.67345627342415, "VFEND": 39.69545904632764, "VORICONAZOLE": 16.482551629034095, "VYXEOS": 91.18708181728309, "XELJANZ": 2.659072250323589}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6454.json
index 7922672d484..b49973be1eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6454.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6454.json
@@ -1 +1 @@
-{"TAMIFLU": 109.02266483115554}
\ No newline at end of file
+{"null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6455.json
index 31c91a91e3b..80be54e9b32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6455.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6455.json
@@ -1 +1 @@
-{"BUSULFAN": 21.14592111819901, "CELLCEPT": 6.152738908644116, "CICLOSPORIN": 5.1339691143129, "CYTARABINE": 9.477767992865791, "DEXAMETHASONE": 8.676261447654184, "FENTANYL": 4.227290972781793, "JANUMET": 7.136981755749122, "SOLIRIS": 8.790475350240348}
\ No newline at end of file
+{"null": 4.917374261405082}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6456.json
index 09a9230c05c..16360c1f85a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6456.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6456.json
@@ -1 +1 @@
-{"CELLCEPT": 7.932109869024526, "CICLOSPORIN": 5.764023370367196, "CIMZIA": 6.976463880571726, "SIMPONI": 8.583554706470188, "STELARA": 6.840133106615349}
\ No newline at end of file
+{"SOMATROPIN": 278.57056558083264, "SOMAVERT": 2152.5677485815067, "null": 4.907323680180788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6457.json
index 9a89ce869a1..f5110940a4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6457.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6457.json
@@ -1 +1 @@
-{"ANAKINRA": 108.9085412381968, "GANCICLOVIR": 261.0318101212616, "null": 1.2064544046879329}
\ No newline at end of file
+{"BYDUREON": 20.129467465685103, "BYETTA": 102.04665456066388, "JANUMET": 60.31417974484709, "JANUVIA": 66.15063661684395, "ZYPREXA": 19.914807531028707, "null": 0.1870502799492828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6458.json
index 784dd0be26e..7bf07a22062 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6458.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6458.json
@@ -1 +1 @@
-{"null": 1.6090640055768926}
\ No newline at end of file
+{"IRBESARTAN": 188.33467845780336, "null": 0.4654227171731536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6459.json
index ca45fb856cc..083db95d417 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6459.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6459.json
@@ -1 +1 @@
-{"CYTARABINE": 20.861977227008, "GANCICLOVIR": 138.39174146074512}
\ No newline at end of file
+{"ABILIFY": 35.78589316191043, "BYDUREON": 8.362092755784401, "CIMZIA": 41.84398261048992, "FASENRA": 27.578482382301814, "HIZENTRA": 30.608312599723156, "JANUVIA": 3.355479327212588, "OCALIVA": 28.186777059639294, "RUCONEST": 52.37275706918357, "null": 1.6489341796861592}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/646.json
index 7c4fafed809..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/646.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/646.json
@@ -1 +1 @@
-{"BUPIVACAINE": 122.6566059986434, "FENTANYL": 14.485197907476818, "SPINRAZA": 96.45144110812238, "null": 1.9130296247177248}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6460.json
index cf782490df7..925d99ddf9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6460.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6460.json
@@ -1 +1 @@
-{"CELLCEPT": 11.665934384057923, "METHOTREXATE": 4.958864340765277, "PEGASYS": 2.442649027553118, "ROACTEMRA": 13.891886005784276, "STELARA": 3.69733247732768}
\ No newline at end of file
+{"AVAMYS": 4.292385665396005, "CICLOSPORIN": 1.906638005906263, "COMBIVIR": 5.824935971387321, "COMIRNATY": 0.0649909665133803, "KEPPRA": 2.9865389916017437, "LEVETIRACETAM": 15.112956368947549, "VAXZEVRIA": 0.0921169382791426, "null": 5.894828182631127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6461.json
index 68e53eae73b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6461.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6461.json
@@ -1 +1 @@
-{"CELLCEPT": 6.168940989865584, "CICLOSPORIN": 8.42508037930584, "KEPPRA": 4.458761130232161, "ORKAMBI": 37.72375508149661, "TOBRAMYCIN": 53.40531967015604}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6462.json
index 929c83c07ca..1d7c88973e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6462.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6462.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 28.485077342419917, "MEPOLIZUMAB": 30.23540190848667, "SPINRAZA": 60.99532952499428, "SYNAGIS": 607.4683976830942}
\ No newline at end of file
+{"null": 4.590053181210944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6463.json
index 13d7616e138..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6463.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6463.json
@@ -1 +1 @@
-{"CICLOSPORIN": 2.5929868379700505, "KEPPRA": 3.931104252029086, "KEYTRUDA": 1.633129483603515, "ORKAMBI": 34.55838598085397, "PEGASYS": 2.957090187807436, "PEGINTRON": 4.110125124260783, "PRIVIGEN": 23.70586074885136, "null": 1.056871006210791}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6464.json
index d2c9c93ea7a..528ceb26174 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6464.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6464.json
@@ -1 +1 @@
-{"BIKTARVY": 45.13149165628347, "CANAKINUMAB": 1284.7406007768789, "PEGASYS": 7.061844426530764}
\ No newline at end of file
+{"BRIDION": 20.362214274538324, "COMIRNATY": 0.2009725754039314, "GARDASIL": 10.340098354904514, "KAFTRIO": 24.10695056139572, "ROTATEQ": 20.622532025437835, "SPIKEVAX": 3.451844079261878, "null": 0.9571180954275827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6465.json
index cd6f064af09..567a59e4dd7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6465.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6465.json
@@ -1 +1 @@
-{"ARAVA": 2.528507992149643, "BENLYSTA": 4.156583469456789, "BUDESONIDE": 5.517517911099858, "CELLCEPT": 3.573527053201716, "CICLOSPORIN": 5.06121999215259, "COBIMETINIB": 51.45739142043528, "CYTARABINE": 4.427158217358356, "ENBREL": 6.379295281905739, "RITUXIMAB": 4.361100585922058, "SPINRAZA": 25.57541487592364, "SYNAGIS": 25.409601766476616, "TAMIFLU": 4.256901990761142, "TRACLEER": 3.654001643077791, "XELJANZ": 1.5729289545698704}
\ No newline at end of file
+{"COMIRNATY": 0.2217707379252678, "FENTANYL": 56.56351118497405, "LACOSAMIDE": 117.70002922557444, "null": 0.5958071208153576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6466.json
index 1194868a2e9..e75e91ae846 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6466.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6466.json
@@ -1 +1 @@
-{"ABILIFY": 1.2813656307392718, "ABRAXANE": 10.89664039951243, "ADCETRIS": 6.90516272421026, "AFINITOR": 32.928356301331306, "ALEMTUZUMAB": 5.265153621638745, "ALIMTA": 16.13262891593914, "ATEZOLIZUMAB": 11.961241494089322, "AVASTIN": 1.1504611405801723, "AVELUMAB": 8.365874232351949, "AXITINIB": 5.801531428388537, "AZACITIDINE": 4.512906102551736, "BENRALIZUMAB": 5.124956793220637, "BEVACIZUMAB": 3.0566644517396244, "BORTEZOMIB": 1.1746478228254822, "BRAFTOVI": 1.199717761795452, "BUSULFAN": 4.553334006101009, "CABOMETYX": 1.571382700603034, "CAELYX": 2.416346374017764, "CAPECITABINE": 3.553683386549746, "CARMUSTINE": 8.776898531720585, "COTELLIC": 2.678370267489312, "CUBICIN": 6.1574672326928725, "DABRAFENIB": 8.993253828545377, "DARZALEX": 1.3182252725884318, "DEXAMETHASONE": 1.281053728260501, "DOCETAXEL": 2.8653892941791006, "DOXORUBICIN": 3.712798630356106, "ENBREL": 1.348334387371113, "ENTYVIO": 1.2256460278445418, "EVEROLIMUS": 17.09063871947472, "FASENRA": 1.191448108714943, "FASLODEX": 1.827442204044922, "FILGRASTIM": 4.767284495053123, "FULVESTRANT": 2.8620424005194227, "GANCICLOVIR": 1.5488379855503651, "GEFITINIB": 4.128659506926195, "HALAVEN": 5.133553341464911, "HERCEPTIN": 4.936085658016009, "IBRANCE": 2.468327104113717, "ICLUSIG": 1.349999792300572, "IMFINZI": 20.84180021060519, "INCIVO": 1.071897995841716, "INFLIXIMAB": 4.943794564730101, "INLYTA": 1.0955938448140523, "IPILIMUMAB": 28.607869287609, "IRESSA": 6.517559829522712, "JAKAVI": 2.0949123610883578, "JEVTANA": 1.6809710133966524, "KEYTRUDA": 23.006069446903247, "KISQALI": 10.406482214027596, "KYPROLIS": 4.666072869667799, "LEFLUNOMIDE": 2.2903918331519293, "LEMTRADA": 3.757755789756212, "LIBTAYO": 22.17963797527833, "LYNPARZA": 4.945725390177708, "MABTHERA": 5.992381102178824, "MEKINIST": 3.779837005069093, "METHOTREXATE": 2.622805531827365, "MIDAZOLAM": 1.7714628367703107, "MULTAQ": 1.5972970582705368, "MYCOPHENOLATE": 1.2763862968653488, "NEULASTA": 1.8758599873034696, "NIVOLUMAB": 12.63028930487864, "OLAPARIB": 6.580111946942954, "OPDIVO": 22.54156935062784, "OSIMERTINIB": 53.44695903828789, "PACLITAXEL": 6.586848759406368, "PEGINTRON": 1.3944145400273629, "PEMBROLIZUMAB": 30.10659730805594, "PEMETREXED": 7.623794091325042, "PREGABALIN": 1.5439375707039895, "RAPAMUNE": 20.949903577099384, "RIBOCICLIB": 4.221716719579039, "RINVOQ": 1.0088324920957972, "RITUXIMAB": 1.2888425074802428, "ROACTEMRA": 1.7804790231726355, "SPRYCEL": 1.801588305033409, "TAGRISSO": 41.91260667605256, "TAXOTERE": 3.392565185806798, "TEMSIROLIMUS": 26.033960533213502, "THALIDOMIDE": 2.956133445462064, "TICAGRELOR": 1.530717754311274, "TORISEL": 17.297661059169375, "TRELEGY": 1.2880847111056493, "TRODELVY": 13.655155478146348, "VELCADE": 5.55748686591266, "XALKORI": 11.01864522069129, "YERVOY": 7.427405654605455}
\ No newline at end of file
+{"COMIRNATY": 0.2464925055019204, "null": 2.29524188181441}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6467.json
index 168d20f617b..246327acbd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6467.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6467.json
@@ -1 +1 @@
-{"FENTANYL": 7.207044266393752, "KEPPRA": 4.618967259848595, "OLANZAPINE": 9.08012560922131, "null": 2.13732309411946}
\ No newline at end of file
+{"BUDESONIDE": 2.782245902870621, "BYDUREON": 63.41533752902963, "BYETTA": 19.66679124523517, "null": 5.906479076743343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6468.json
index 47f3c2c75ba..92f86feeed4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6468.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6468.json
@@ -1 +1 @@
-{"null": 1.3278303894342487}
\ No newline at end of file
+{"null": 2.143246175282272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6469.json
index a0a55ed1597..ae0faeb9507 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6469.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6469.json
@@ -1 +1 @@
-{"NEXAVAR": 6.331969999942376}
\ No newline at end of file
+{"AUBAGIO": 1.8470346180765336, "BENLYSTA": 1.8086900634680003, "BIKTARVY": 6.3712044032950805, "CIMZIA": 12.84132044178221, "EPCLUSA": 41.02321788655625, "EVENITY": 6.336179286098685, "EYLEA": 2.9997122816033284, "FAMPYRA": 4.247959276700852, "FORXIGA": 3.3085723725597003, "HARVONI": 4.826400603707151, "HUMIRA": 4.050126509995973, "IBRANCE": 2.8321629379923974, "INSULIN": 2.8671034074035173, "JANUMET": 1.801764563478084, "KEPPRA": 0.944470231969451, "LANTUS": 3.724546173085043, "LATUDA": 4.296082312664163, "LEVEMIR": 6.965952669784408, "MEPOLIZUMAB": 7.068590195677527, "REMSIMA": 161.68423900628736, "SAXENDA": 3.6304570118362287, "SOFOSBUVIR": 99.27973837023455, "SPIKEVAX": 0.413745251955501, "SUTENT": 0.5618031746009913, "TOUJEO": 8.955473371269257, "TRELEGY": 3.673420498349929, "TRUVADA": 0.2964541545831557, "VAXZEVRIA": 0.5372299639749686, "VICTOZA": 3.1674155742026047, "XELJANZ": 10.243679903439002, "XTANDI": 11.041481994955625, "null": 1.3521041487633585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/647.json
index 9d9e1052b8e..921102b4a58 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/647.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/647.json
@@ -1 +1 @@
-{"BENZODIAZEPINES": 95.37984249360052, "BUPIVACAINE": 21.26904191385626, "CELECOXIB": 8.565377256697056, "CICLOSPORIN": 2.025468324129245, "CLOPIDOGREL": 1.280824611152062, "ESOMEPRAZOLE": 27.869898043038837, "FENTANYL": 6.642433644537372, "GARDASIL": 4.340270932646788, "IBUPROFEN": 3.518931992257468, "INSULIN": 6.1074669174394325, "MIDAZOLAM": 6.259808284129397, "NUCALA": 2.7301664594454587, "OLANZAPINE": 3.113231895045645, "SHINGRIX": 2.481457877917973, "TWINRIX": 6.4112930980695575, "ZOSTAVAX": 1.1583124377122314, "null": 2.1124531043519053}
\ No newline at end of file
+{"SPIKEVAX": 30.463875443970583}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6470.json
index 1dfe112f9ae..2057f6f84f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6470.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6470.json
@@ -1 +1 @@
-{"AFINITOR": 1.6839934043659923, "ALIMTA": 3.910957483134511, "AMINOSALICYLIC": 3.414693284495831, "AVASTIN": 1.9835201821843875, "AZACITIDINE": 7.678725651460646, "BEDAQUILINE": 26.054463571380836, "BEVACIZUMAB": 1.3418569774440336, "BIKTARVY": 2.04675400184223, "BRIDION": 4.496556945590275, "BUDESONIDE": 3.869506655743951, "BUSULFAN": 2.3874695951704363, "CABOMETYX": 2.567507490406236, "CELLCEPT": 1.0615788367559909, "CHOLESTAGEL": 69.075898608453, "CICLOSPORIN": 2.1047257618856654, "CYTARABINE": 1.6065993419179057, "DELAMANID": 6.737830220635362, "DEXAMETHASONE": 3.788054047904079, "DOCETAXEL": 1.762547317188906, "ERBITUX": 5.316058586044711, "ESBRIET": 7.325428863737445, "FASENRA": 1.794194009151659, "FENTANYL": 3.6752909157471545, "FIRDAPSE": 5.778507363024353, "HALAVEN": 10.589825367498312, "HIZENTRA": 1.5122839035508304, "IBRANCE": 1.000810729425481, "INCRUSE": 10.127286651124235, "INLYTA": 3.533393888891544, "IRESSA": 7.775588441863413, "KAFTRIO": 2.9048045081518765, "KALYDECO": 9.462653878567552, "KEYTRUDA": 4.381583129605632, "LENVIMA": 10.744055730438356, "MEKINIST": 1.3300893784963257, "METHOTREXATE": 1.250553002685022, "MIDAZOLAM": 2.8169399658541883, "NEULASTA": 1.99038968244762, "NUCALA": 1.232058942466417, "OFEV": 12.751779894493763, "OPDIVO": 1.0576392437510054, "OPSUMIT": 1.279542039548982, "ORKAMBI": 13.334877501826746, "PAZOPANIB": 32.419494668662544, "PEMBROLIZUMAB": 2.01628070961675, "PEMETREXED": 2.871185898940192, "REMDESIVIR": 7.581352114885695, "REVATIO": 1.4633842016111245, "ROACTEMRA": 1.0268947885752984, "SPINRAZA": 11.107134247403348, "SPRYCEL": 1.868570366363777, "SUFENTANIL": 3.622375758224646, "SUTENT": 1.0945947014956998, "SYNAGIS": 3.628023829160131, "TAGRISSO": 6.265809169077893, "TAMIFLU": 1.6045572203793468, "TRACLEER": 3.285757160738092, "TRELEGY": 8.334015459512946, "VEKLURY": 6.45504451922386, "VFEND": 1.7940228872328907, "VOTRIENT": 21.79921209366731, "XALKORI": 1.9145793858365965, "null": 1.1804043232964774}
\ No newline at end of file
+{"null": 0.7934161955149596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6471.json
index 36de0b75c7c..6f04b7c8984 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6471.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6471.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 20.207553212424017, "VOTRIENT": 13.39582429963201}
\ No newline at end of file
+{"null": 9.161409162330925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6472.json
index 14b0dfb8762..ff463f2dbed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6472.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6472.json
@@ -1 +1 @@
-{"KEPPRA": 35.78042598318595}
\ No newline at end of file
+{"ABILIFY": 3.770383544607679, "ACTOS": 0.8671840581423278, "ACTRAPID": 1.90798578755888, "AERIUS": 1.837110172542876, "ALL": 2.10938882077663, "APIDRA": 0.5017836339252495, "APIXABAN": 0.2740009624964004, "ARIPIPRAZOLE": 2.744837922781824, "ASENAPINE": 8.797260050481878, "ATRIPLA": 0.0433887259885968, "AVANDIA": 0.0785213986234186, "AXURA": 10.644863180880686, "BENZODIAZEPINE": 13.518373231367365, "BENZODIAZEPINES": 5.675225325817674, "BETA": 8.088083989614736, "BETADORM": 80.7833639710511, "BIKTARVY": 0.2879800317178973, "BRINTELLIX": 2.1004933188735357, "BUPIVACAINE": 1.9774586861854109, "BUPRENORPHINE": 1.181289496855778, "BYETTA": 0.1039744529720566, "CELECOXIB": 0.8637152989615661, "CELLCEPT": 0.0833051375173279, "CHAMPIX": 1.1290939102847308, "CICLOSPORIN": 0.0903240386430883, "CIRCADIN": 12.446035773319412, "CLOPIDOGREL": 0.54185554947633, "COAPROVEL": 0.8211417894184326, "CYMBALTA": 2.6319792177212307, "DESLORATADINE": 4.923887587801009, "DULOXETINE": 5.327988063727441, "ELIQUIS": 0.210347372700216, "EMPAGLIFLOZIN": 0.9591982482705528, "EMTRICITABINE": 1.0507283974199804, "ESOMEPRAZOLE": 12.26734475450065, "EXFORGE": 0.465138926807043, "FENTANYL": 0.5850296053771717, "FIRDAPSE": 0.4484509651408352, "FYCOMPA": 6.698387422911089, "GENVOYA": 1.0162852036349783, "GLIBENCLAMIDE": 4.961168312689323, "GLUCAGON": 7.143546894706867, "GUANFACINE": 10.284906114126846, "HUMALOG": 1.0715464073444765, "HYDROCHLOROTHIAZIDE": 2.0235000204827176, "IBUPROFEN": 15.42563573305376, "INCRUSE": 0.6011413846811713, "INSULIN": 2.440935657898821, "INVEGA": 10.229395938062794, "IRBESARTAN": 0.8416518904479424, "IRON": 1.4154771379416815, "JANUMET": 0.5437648337805223, "JANUVIA": 0.4340149211207783, "JARDIANCE": 0.1258487956190317, "KAFTRIO": 0.4895214420169141, "KEPPRA": 1.959789578726569, "LACOSAMIDE": 1.99702080445486, "LANTUS": 1.5753598203169812, "LATUDA": 1.7682508959713277, "LEVEMIR": 0.7491312776001781, "LEVETIRACETAM": 1.8773315236571944, "LEVODOPA": 2.1956543299060334, "LYRICA": 3.500605531905709, "MELATONIN": 25.5854285212531, "MICARDIS": 0.4797948989225793, "MIDAZOLAM": 2.2476662071706257, "NALOXONE": 2.196628648644798, "NOT": 1.4360679744795288, "NOVORAPID": 3.060635228388274, "OLANZAPINE": 7.554184079293921, "OPIOIDS": 7.009035091167111, "OXYBUTYNIN": 2.7752177972143093, "PANTOPRAZOLE": 1.364208342442477, "PEGASYS": 0.0865587076983297, "PEGINTERFERON": 0.1670503381890891, "PEGINTRON": 0.0716538782240814, "PERAMPANEL": 9.741663556189955, "PIOGLITAZONE": 5.9082427349603925, "PLAVIX": 0.2730816455814731, "PRADAXA": 0.8006294716262418, "PREGABALIN": 4.753450252466519, "PROPRANOLOL": 6.047812754570971, "RANOLAZINE": 1.535378770095508, "REMICADE": 0.3950232725025666, "RISPERIDONE": 1.3123623405056632, "RIVAROXABAN": 6.408274978644332, "SAXENDA": 0.1602246469493863, "SIFROL": 1.3723968372153998, "SILDENAFIL": 1.014181827907466, "SONATA": 36.05160301566608, "STALEVO": 0.8433509220465522, "SUBOXONE": 1.0006306511359238, "SYCREST": 1.1830649347281106, "TELMISARTAN": 1.906931603417956, "TOUJEO": 0.4588395224447513, "TRELEGY": 0.19225911524753, "TRESIBA": 5.234611420794442, "TRICYCLIC": 36.2364660944628, "UNKNOWN": 4.922599400571227, "UNSPECIFIED": 4.52359954519825, "VALDOXAN": 30.09070341614108, "VALSARTAN": 0.7542444430996142, "VAXZEVRIA": 0.0029410479082339, "VFEND": 0.1392374813097867, "VIAGRA": 1.8806834931199043, "VICTOZA": 0.3834985894869108, "VILDAGLIPTIN": 4.282044848885023, "VIMPAT": 1.2798212965827869, "XARELTO": 0.3234496032030989, "XELJANZ": 0.1098874485871494, "XYREM": 0.8354738123570441, "ZALASTA": 17.66585940476954, "ZYPREXA": 7.941652174465774, "null": 6.253389149358762}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6473.json
index 1bbf7e45739..b698f86fc66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6473.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6473.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 1.741895465914639, "BEDAQUILINE": 2.575154579114072, "BENZODIAZEPINE": 33.52905914479428, "BUPRENORPHINE": 6.882243667861207, "CANNABIDIOL": 9.56235383226558, "DULOXETINE": 5.766179691677862, "ENTRESTO": 1.170605138870347, "FENTANYL": 2.2961316950707533, "IBUPROFEN": 4.962939752374636, "IRBESARTAN": 4.114685025399158, "KEPPRA": 1.471563850822151, "LOXAPINE": 64.84474681924394, "LYRICA": 3.0837628093296803, "MIDAZOLAM": 6.547846293031295, "NOT": 3.0863450055831905, "OLANZAPINE": 7.454475427875071, "PANTOPRAZOLE": 2.670251031494801, "POPPERS": 59.76871710773202, "PREGABALIN": 9.93551915483845, "SUTENT": 1.048803959812254, "ZYPREXA": 1.961448772498716, "null": 4.60836816992855}
\ No newline at end of file
+{"ABACAVIR": 15.989563109724989, "ABILIFY": 0.5288971495040086, "ADALIMUMAB": 0.1226884104991343, "AFINITOR": 0.0811540787917509, "AIMOVIG": 0.1516874378871515, "ALL": 2.113627040119439, "AMINOSALICYLIC": 0.2362687708191199, "ANTIBIOTICS": 2.0501502427803837, "APIDRA": 2.351196010934683, "APIXABAN": 3.092755092049531, "APROVEL": 1.153256933054719, "ARANESP": 4.960163562410982, "ARAVA": 0.4942032475296722, "ARIPIPRAZOLE": 3.134694101813549, "ATRIPLA": 0.0275108177565193, "AUBAGIO": 0.139454595466785, "BENLYSTA": 0.1902786368746291, "BENZODIAZEPINE": 13.86563142128302, "BENZODIAZEPINES": 5.774684714109031, "BETAFERON": 0.4565637094010628, "BETMIGA": 2.4986282477666037, "BEVACIZUMAB": 0.5667867101618984, "BEVESPI": 14.79702221649479, "BIKTARVY": 0.4560171914201096, "BORTEZOMIB": 1.9205047210425883, "BOSULIF": 1.796081580496752, "BRAFTOVI": 0.5507489747336393, "BRILIQUE": 1.703678421814157, "BRINTELLIX": 0.3915719870092736, "BRIVIACT": 3.397187050680177, "BUDESONIDE": 0.3801324802261474, "BUPRENORPHINE": 9.572574174986295, "BYDUREON": 4.168993560527213, "BYETTA": 1.921768621168593, "CANNABIDIOL": 1.0977056689579463, "CELLCEPT": 0.1015722416584497, "CERTOLIZUMAB": 9.408359506921531, "CHAMPIX": 1.0620184948124498, "CIALIS": 2.09179562207739, "CICLOSPORIN": 0.0732947090698717, "CIMZIA": 0.3541006762784085, "CLOPIDOGREL": 0.2753281545493527, "COAPROVEL": 0.5855755966832008, "COMIRNATY": 0.0020902383034908, "CYMBALTA": 2.6432747585056453, "DALIRESP": 8.952161062495813, "DAPTOMYCIN": 4.020798860586919, "DARBEPOETIN": 10.035865815699998, "DEXAMETHASONE": 0.1608962603897401, "DULOXETINE": 1.7537290363883795, "ELIQUIS": 0.9715933227764806, "ENBREL": 0.7695618222446289, "ENTRESTO": 0.102394522553566, "EPCLUSA": 0.551968029132287, "ESBRIET": 0.506425989180007, "ESOMEPRAZOLE": 0.4892967094319483, "EVISTA": 0.5513080959387121, "FAMPYRA": 3.2404317007358343, "FASENRA": 1.334688880572435, "FASLODEX": 1.1947433031037047, "FENTANYL": 6.376195900955742, "FIASP": 1.018804605242777, "FIRDAPSE": 0.7443365786088466, "FORSTEO": 0.3958213618757001, "FORXIGA": 4.693045002269752, "GLIBENCLAMIDE": 1.807981064731327, "GUANFACINE": 11.072050637112987, "HUMALOG": 1.1797604806512036, "HUMIRA": 0.5140901147715164, "HYDROCORTISONE": 0.7016291068020849, "HYDROXOCOBALAMIN": 32.936759697651475, "IBRANCE": 0.927625628382306, "IBUPROFEN": 3.095496506239056, "ICLUSIG": 0.6197394390391463, "IKERVIS": 6.831764581064476, "INCRUSE": 0.8119098734792235, "INLYTA": 0.5835927544653109, "INSULIN": 1.1311349385695744, "INVEGA": 2.4435521690193496, "IRBESARTAN": 0.6942744274924117, "IRESSA": 0.6606379428857753, "JANUMET": 0.6072956173564842, "JANUVIA": 0.4466962785952822, "JARDIANCE": 0.162356410218471, "KEPPRA": 1.8346647501126496, "LACOSAMIDE": 0.9004796001466124, "LANTUS": 1.6968216258047084, "LATUDA": 0.3886083134612695, "LEVEMIR": 0.5479188454749014, "LEVETIRACETAM": 0.4486059872038904, "LEVODOPA": 4.184631161899871, "LEVOFLOXACIN": 0.2346057458034824, "LURASIDONE": 2.365366297291258, "LYNPARZA": 1.678499990535971, "LYRICA": 4.145703330790836, "MELATONIN": 4.247300242771841, "METHOTREXATE": 0.2626857277382515, "MICARDIS": 0.3541871548923715, "MIDAZOLAM": 4.460075911537511, "MIMPARA": 0.7029644709855691, "MIRABEGRON": 3.649053886918591, "MYCAMINE": 3.040676915460081, "NALOXONE": 2.365366297291258, "NEXAVAR": 0.0849723602300727, "NOT": 1.260536844718181, "NOVORAPID": 0.8664275905826897, "OLANZAPINE": 2.1395886964368542, "ONGLYZA": 4.727251592888439, "OTHER": 7.512509041822097, "OXYBUTYNIN": 0.9818640298584131, "PALIPERIDONE": 3.538349011329053, "PANTOPRAZOLE": 0.9262342200807808, "PEGASYS": 0.0493495928282359, "PLAVIX": 0.5367793245879837, "PREGABALIN": 7.811511987244406, "QUTENZA": 1.6001308875429177, "RAPAMUNE": 1.8732237400970773, "RELVAR": 0.6571634684208941, "REVATIO": 1.81357096794818, "RINVOQ": 1.2169945874372756, "RISPERIDONE": 1.995397921631496, "RITUXIMAB": 0.13897474503262, "ROACTEMRA": 0.3221381856635916, "SAXENDA": 0.8223248714843693, "SILDENAFIL": 2.0872283339887896, "SIMPONI": 0.0706968138781314, "SKELETAL": 101.95006512172726, "SKYRIZI": 1.1390064335346424, "SOMATROPIN": 2.0170800566277776, "STALEVO": 0.7148013140853103, "SUBOXONE": 6.232903123987146, "SUTENT": 0.2974083468968358, "SYNAGIS": 0.3032169757676733, "TAGRISSO": 0.8476349978736493, "TAMIFLU": 0.194871026609648, "TESTOSTERONE": 3.0406896463845103, "TICAGRELOR": 0.5313239050586209, "TOUJEO": 3.832139251058136, "TOVIAZ": 2.1827080823906493, "TRELEGY": 0.7550435365248174, "TRESIBA": 1.048079475055273, "TRULICITY": 0.3906219762036251, "TRUVADA": 0.0663150094774878, "UNKNOWN": 8.231470919708164, "UNSPECIFIED": 13.814003587134271, "VAXZEVRIA": 0.0266939610772575, "VFEND": 0.27322174838141, "VIAGRA": 8.308365312393084, "VICTOZA": 0.3488680685954253, "VIMPAT": 2.171438806846552, "XALKORI": 0.4572785508914077, "XELJANZ": 4.379137296804797, "XOLAIR": 0.1946136204966235, "XTANDI": 0.9373131376073992, "XYREM": 3.5747610497699687, "ZYPREXA": 0.8833310220179765, "null": 3.515635285102262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6474.json
index 8d7fd3d70f1..32600fbe3e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6474.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6474.json
@@ -1 +1 @@
-{"ABILIFY": 2.921610012116054, "ARIPIPRAZOLE": 2.259781854904412, "BIKTARVY": 3.7420826116033674, "BRINTELLIX": 3.4187120160276314, "BUPRENORPHINE": 1.6795551068449588, "IBUPROFEN": 3.323374485896906, "LOXAPINE": 59.6502768504546, "LYRICA": 4.087179183234894, "MELATONIN": 6.507163746014482, "MIDAZOLAM": 8.142820011314287, "OLANZAPINE": 9.653937600898152, "PREGABALIN": 13.702285488775294, "ZYPREXA": 1.6074706606047506, "null": 9.288618320469602}
\ No newline at end of file
+{"null": 2.468161136512688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6475.json
index dc711e58b0d..3e880c3ede7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6475.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6475.json
@@ -1 +1 @@
-{"null": 3.1548067533935624}
\ No newline at end of file
+{"ABACAVIR": 1.220508772544313, "ABATACEPT": 6.017868286319677, "ABILIFY": 0.1713767848961401, "ADALIMUMAB": 7.699157809595462, "ADCETRIS": 3.185199069056277, "AFINITOR": 0.1209107146365846, "ALEMTUZUMAB": 1.890412464698092, "AMIKACIN": 3.1424090786547647, "AMINOSALICYLIC": 5.107189440060783, "ANAKINRA": 9.112130052777273, "APIDRA": 0.7758468556069884, "APIXABAN": 6.219011474160773, "APREPITANT": 1.880426224372818, "ARAVA": 2.847885062246545, "ASPARAGINASE": 0.7658018192173992, "ATAZANAVIR": 1.983054844373285, "ATEZOLIZUMAB": 3.1791809195991423, "AVAMYS": 0.5191044839170122, "AVASTIN": 2.5613615753747645, "AZACITIDINE": 1.5077986114783273, "AZATHIOPRINE": 0.7973490332200251, "BASILIXIMAB": 1.6841800050932076, "BEDAQUILINE": 15.63819680324032, "BENZODIAZEPINE": 3.349644179158676, "BEVACIZUMAB": 0.8245088553490435, "BIKTARVY": 1.134199261964224, "BORTEZOMIB": 2.995250424325476, "BRILIQUE": 0.3163530059400943, "BRINTELLIX": 0.2654984356193787, "BRIVIACT": 0.8687333358197641, 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0.7873506385646273, "REAGILA": 9.950928045305458, "REMDESIVIR": 2.645588462887244, "REMSIMA": 9.529521865024185, "REVATIO": 1.8684889727619645, "RIBAVIRIN": 1.0300138130195322, "RITUXIMAB": 3.147373916101883, "ROACTEMRA": 10.91549229614474, "RUCONEST": 67.23278723665948, "SAXENDA": 0.3962234197331393, "SILDENAFIL": 0.5179927745780356, "SIMPONI": 0.1695216428892814, "SIRTURO": 20.168822450481315, "SPIKEVAX": 0.0305419631534456, "SPRYCEL": 4.016194459524272, "STELARA": 0.2215401612511627, "STIVARGA": 0.1838268873844795, "SUBOXONE": 5.533815306201888, "SUTENT": 0.0757654490138606, "TAMIFLU": 1.1695938928445628, "THALIDOMIDE": 1.049819047333919, "TOCILIZUMAB": 19.649817627527007, "TOUJEO": 4.008458175524142, "TOVIAZ": 1.9375481281811564, "TRELEGY": 0.3695873220618904, "TRUVADA": 0.096924764517537, "UROREC": 3.586827280680069, "VENETOCLAX": 2.4442210024458744, "VFEND": 0.4160266285302663, "VIAGRA": 3.238322798031636, "VICTOZA": 0.2730916612192053, "XELJANZ": 2.153782772987741, "XELODA": 2.107817980361163, "XOLAIR": 0.640324828868848, "XTANDI": 1.2342587834458356, "XYREM": 3.297483072452432, "YERVOY": 3.471437852717989, "ZELBORAF": 6.163320274795139, "null": 1.073911197169633}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6476.json
index 65432659e0f..11aee190f9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6476.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6476.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.5296113348748246, "ADEMPAS": 1.867867183906501, "ANORO": 1.63078535689249, "APIDRA": 1.5015601741370823, "ATRIPLA": 1.337187588350958, "AUBAGIO": 2.0063858697199, "AZACITIDINE": 1.202115542801805, "BETMIGA": 14.005895435295397, "BRINTELLIX": 1.5809814419980577, "CHAMPIX": 2.09095290487465, "COAPROVEL": 2.082827240578652, "COSENTYX": 1.1271430825601298, "CYMBALTA": 1.119046125744932, "DULAGLUTIDE": 3.5565773784015, "EMPAGLIFLOZIN": 12.240661494588526, "ENTACAPONE": 3.1450774877689414, "ENTRESTO": 2.604135152429276, "ENZALUTAMIDE": 3.5114183829130763, "EXFORGE": 3.9922118844832912, "FAMPRIDINE": 5.931940916156075, "FAMPYRA": 1.2940342992356175, "FASLODEX": 1.122376192751617, "FORSTEO": 5.715341974846749, "FORXIGA": 19.0907632991636, "GARDASIL": 1.1289505581940191, "HUMALOG": 2.106559315281079, "INCRUSE": 2.688744731727493, "INTELENCE": 12.124317213615468, "INVOKANA": 2.1351278355626984, "IRBESARTAN": 1.2640416172588909, "JANUMET": 1.1329474638853128, "JARDIANCE": 25.511179269782065, "KESIMPTA": 1.438343917568162, "LANTUS": 2.0080214006230075, "LATUDA": 1.3921008814134674, "MELATONIN": 1.304117362521549, "MICARDIS": 1.6263821009629835, "MIRABEGRON": 8.62787136213413, "OXYBUTYNIN": 4.921441762447618, "PEGINTRON": 1.991257384529049, "RASILEZ": 1.4837724869764433, "RELVAR": 1.1078069626609166, "RINVOQ": 1.580295461875896, "SILODYX": 14.650789830120049, "TOUJEO": 1.0441951760987218, "TOVIAZ": 11.34076737873998, "TRELEGY": 1.7259756952625709, "TRUVADA": 1.4092700734269143, "VALSARTAN": 2.174530238033752, "VIAGRA": 1.3198287022768247, "XELJANZ": 1.4326636777681825, "XTANDI": 3.2310860258787715, "XYREM": 3.122479395364816, "ZOSTAVAX": 1.3025667052359604, "ZYPREXA": 1.4034550359199585, "null": 1.2877023098471776}
\ No newline at end of file
+{"null": 4.385558267650419}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6477.json
index 0d1dd033093..c6b81cd0bc6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6477.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6477.json
@@ -1 +1 @@
-{"ANAKINRA": 39.2025044059492, "null": 1.712875212803881}
\ No newline at end of file
+{"ABILIFY": 5.961659895892341, "ARIPIPRAZOLE": 4.343544554237446, "BRINTELLIX": 4.236518316439188, "BRIVIACT": 2.650526862832382, "BUPRENORPHINE": 2.680678589082045, "CHAMPIX": 3.650554367449632, "CIRCADIN": 30.720896867071737, "CLOPIDOGREL": 0.2216493457193019, "COMIRNATY": 0.0076972152592664, "CYMBALTA": 2.070029299914488, "DESLORATADINE": 8.434215511454896, "DULOXETINE": 8.796547488127727, "ELIQUIS": 0.1698599808932925, "GARDASIL": 0.7733883842705703, "HUMALOG": 0.2094618852322446, "IBUPROFEN": 1.720460600267918, "IVABRADINE": 17.022503347519358, "KAFTRIO": 4.270311493327137, "KEPPRA": 2.0496227087772483, "LACOSAMIDE": 2.473835428227112, "LATUDA": 8.39948755539375, "LEVETIRACETAM": 0.841718132245114, "LEVOFLOXACIN": 0.3752880231303981, "LYRICA": 3.449943269395068, "MELATONIN": 106.73625453350212, "OLANZAPINE": 7.832837937521737, "OXYBUTYNIN": 3.4815148195146457, "PREGABALIN": 4.45371246951623, "SUBOXONE": 0.8954825496226159, "TAMIFLU": 1.5741037628121133, "ZYPREXA": 3.0418204352096465, "null": 6.770308093868617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6478.json
index d7c56da4c14..1fde90d8ef4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6478.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6478.json
@@ -1 +1 @@
-{"ADALIMUMAB": 5.7244963659828425, "ANAKINRA": 12.56571645821245, "BENLYSTA": 2.5309394579676234, "CIMZIA": 2.578406131922832, "CLOPIDOGREL": 2.6529248914234174, "COMIRNATY": 1.0999436119571588, "COMPRESSION": 332.39268654815885, "COSENTYX": 2.8142327480251423, "ENBREL": 2.6168142628908115, "ENTYVIO": 1.57730105170645, "FORSTEO": 1.3805316195015824, "GARDASIL": 2.7289772784054187, "HUMIRA": 4.9212726473584345, "IBUPROFEN": 2.2911146316362787, "IPILIMUMAB": 11.23661901865747, "JANUVIA": 1.6272282960306983, "KEYTRUDA": 6.085150867459725, "LEFLUNOMIDE": 8.222074524367118, "METHOTREXATE": 3.1872655644592256, "OPDIVO": 3.054261960266129, "PEGASYS": 1.870967052885377, "PEMBROLIZUMAB": 17.233569810920102, "PLAVIX": 1.3486954276054497, "RINVOQ": 3.702505109587792, "SHINGRIX": 1.234940448902102, "SIMPONI": 2.793992191043352, "STELARA": 1.5912813424031829, "TWINRIX": 4.854045359640742, "XELJANZ": 2.855226304939351, "XOLAIR": 1.1078982091895129, "ZOSTAVAX": 1.067723298361814}
\ No newline at end of file
+{"BUPRENORPHINE": 33.62244515913804, "ELIQUIS": 3.2475724752480013, "FAMPYRA": 17.643092441266454, "FENTANYL": 2.88586002354976, "INCRUSE": 10.543246415066337, "RUBRACA": 12.42558380467375, "SUBOXONE": 213.18254319836905, "XELJANZ": 1.5251003824456686, "XTANDI": 17.542703145611828, "null": 1.2401647270075191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6479.json
index d1f2fe1b5c2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6479.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6479.json
@@ -1 +1 @@
-{"CARMUSTINE": 281.1710476480148}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/648.json
index d918f103d80..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/648.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/648.json
@@ -1 +1 @@
-{"GARDASIL": 4.486955127273264, "KEPPRA": 8.755418048586838, "null": 4.2896695402129}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6480.json
index ea8970e051f..b2f2aefb503 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6480.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6480.json
@@ -1 +1 @@
-{"ADENURIC": 1213.679415045924}
\ No newline at end of file
+{"INCRUSE": 73.12638411309189, "LANTUS": 8.891909490135637, "VAXZEVRIA": 0.3301281946754887, "null": 1.174901136945774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6481.json
index 2a6e5ad601d..4cc5f082da1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6481.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6481.json
@@ -1 +1 @@
-{"APIXABAN": 25.993378412514986, "COVID19": 1.2249583821724472, "GARDASIL": 22.053125387903727, "TOZINAMERAN": 2.206474284552243}
\ No newline at end of file
+{"AIMOVIG": 24.72383676462357, "ESMYA": 478.3268084470686, "null": 1.8264759146952505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6482.json
index c134ba583a5..5f8bbe0b67f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6482.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6482.json
@@ -1 +1 @@
-{"APIXABAN": 996.103608613361, "ELIQUIS": 10.078486062131432, "ESOMEPRAZOLE": 28.03127236743863}
\ No newline at end of file
+{"HUMALOG": 52.14924877783667, "null": 1.7589940062340212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6483.json
index b075305bf9e..ffdeba7a98c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6483.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6483.json
@@ -1 +1 @@
-{"ARANESP": 3.3767239497890564, "AXITINIB": 41.579890874547424, "CICLOSPORIN": 3.247333717713528, "COSENTYX": 7.965017940283153, "EMPAGLIFLOZIN": 25.16137389725629, "FORXIGA": 19.174419530142018, "INLYTA": 11.72398820540779, "JARDIANCE": 15.260105884660032, "LENVIMA": 27.482390398199648, "SUTENT": 1.0800910698914543, "TESTOSTERONE": 194.5021391228964, "null": 1.2123104703047611}
\ No newline at end of file
+{"CIMZIA": 6.132617721590867, "LONSURF": 50.29835026126475, "METFORMIN": 103.4576834254992, "null": 2.250161940172825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6484.json
index 5c79273a7e0..7e8c2e71112 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6484.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6484.json
@@ -1 +1 @@
-{"JAKAVI": 152.31551694094267, "null": 1.2174571444027211}
\ No newline at end of file
+{"HUMALOG": 104.33722136848446, "null": 0.8543727500275625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6485.json
index bac0dacd642..efe1c4fca0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6485.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6485.json
@@ -1 +1 @@
-{"COMBIVIR": 95.8083307570583, "KEPPRA": 6.870752334737723, "LEVETIRACETAM": 8.229104630163784, "null": 3.05879853322794}
\ No newline at end of file
+{"PEGASYS": 35.60219331159884, "ROACTEMRA": 91.21687460292188, "null": 0.5712359299689306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6486.json
index b2c3024e459..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6486.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6486.json
@@ -1 +1 @@
-{"ABILIFY": 1.9868168198169072, "AFINITOR": 1.4264046306064706, "APIDRA": 4.6502909501666005, "CHAMPIX": 2.6919628398941797, "CYTARABINE": 1.5777828285434738, "DEXAMETHASONE": 1.1064616491397083, "EMPAGLIFLOZIN": 9.441444816522113, "FORXIGA": 10.307484050938182, "GARDASIL": 1.4087072913388197, "HUMALOG": 1.2191143020641664, "INSULIN": 7.444265565416608, "IRBESARTAN": 5.399581495360236, "JANUMET": 3.5572962546358764, "JARDIANCE": 10.49512181479786, "LANTUS": 1.6219144497562887, "LATUDA": 9.138487424797011, "OLANZAPINE": 7.217015639482775, "PEGINTRON": 1.0943763548338623, "RIBAVIRIN": 3.9943487712233257, "SYCREST": 25.35471915052848, "VIREAD": 4.57582520644142, "ZYPREXA": 25.09898153193511, "null": 1.3845202338481897}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6487.json
index 25c1581586d..6fc42ed6cc5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6487.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6487.json
@@ -1 +1 @@
-{"OLANZAPINE": 26.074045327665026, "null": 1.29554158417237}
\ No newline at end of file
+{"CERVARIX": 5.4231511804199375, "COMIRNATY": 21.43784098171479, "ELASOMERAN": 24.492341929467337, "GARDASIL": 1.3273082881853502, "HUMIRA": 0.1997463933731413, "JANSSEN": 50.77818884962029, "JCOVDEN": 9.953844508940737, "SPIKEVAX": 2.578317306784124, "TOZINAMERAN": 1.5784811061537891, "VAXZEVRIA": 0.2555249880785284, "null": 0.0019447907647161}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6488.json
index 83ddcdb12ab..ba97df1015a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6488.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6488.json
@@ -1 +1 @@
-{"FENTANYL": 6.061605785391556, "KEPPRA": 3.055436957807088, "null": 2.6693936137508825}
\ No newline at end of file
+{"COMIRNATY": 2.707888001337136, "SPIKEVAX": 0.8384409704025698, "VAXZEVRIA": 0.4518606905518733, "null": 0.2259842738821923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6489.json
index 42a7b919c24..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6489.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6489.json
@@ -1 +1 @@
-{"COMIRNATY": 5.466745188948011}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/649.json
index 419a1f63db4..899c92dc9ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/649.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/649.json
@@ -1 +1 @@
-{"GARDASIL": 17.059728529030046, "null": 3.657729150466252}
\ No newline at end of file
+{"STALEVO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6490.json
index 480b16ad5ca..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6490.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6490.json
@@ -1 +1 @@
-{"COMIRNATY": 16.14731686872899, "ELLAONE": 14.503021723401998, "EVRA": 2.3654009776792018, "SPIKEVAX": 2.8110501066686715, "TOZINAMERAN": 1.1857830607534865}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6491.json
index 5a8a6f2e25d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6491.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6491.json
@@ -1 +1 @@
-{"ABACAVIR": 44.75061526696715, "SPIKEVAX": 1.9259868873263883}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6492.json
index 10dcaa37061..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6492.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6492.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 24.851458710209272, "TOZINAMERAN": 6.738791305197456, "VAXZEVRIA": 2.1368049224706964}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6493.json
index 745cf00987f..56e6d08b391 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6493.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6493.json
@@ -1 +1 @@
-{"COMIRNATY": 2.464852379631598}
\ No newline at end of file
+{"COMIRNATY": 4.182596849841941}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6494.json
index 4823dfa84a9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6494.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6494.json
@@ -1 +1 @@
-{"COMIRNATY": 3.9922588888628496, "EFAVIRENZ": 5.425744246544911, "EVENITY": 3.645073409048223, "IPILIMUMAB": 4.715348616344248, "KEYTRUDA": 6.824011134335908, "MEPOLIZUMAB": 2.648258949268122, "NUCALA": 1.793691637531622, "OPDIVO": 7.063942355122454, "PEMBROLIZUMAB": 13.494303455996013, "SHINGRIX": 5.157116798092937, "SPIKEVAX": 1.4561322268059993, "STELARA": 1.2789941364063555, "TOZINAMERAN": 2.6178996896848004, "VAXZEVRIA": 1.2630417166176082, "ZOSTAVAX": 6.885032098115992}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6495.json
index af2d61b23fc..b5fffaf4307 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6495.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6495.json
@@ -1 +1 @@
-{"CICLOSPORIN": 2.757970477445421, "GARDASIL": 2.072305104696043, "IPILIMUMAB": 11.325017009955308, "KEYTRUDA": 8.695467953802197, "OPDIVO": 9.135383838466224, "PEGASYS": 6.100394054249318, "PEGINTRON": 4.003886628389784, "RITUXIMAB": 8.943281330508277, "null": 1.001566930882512}
\ No newline at end of file
+{"ENTYVIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6496.json
index b577d21e5d2..23946d39a77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6496.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6496.json
@@ -1 +1 @@
-{"ADCETRIS": 8.777759897138928, "ALIMTA": 1.400944703418, "ASPARAGINASE": 1.473805232645462, "AUBAGIO": 6.220133233396325, "AVAMYS": 1.1295141307541, "AVASTIN": 2.167719653710725, "BEDAQUILINE": 3.245713850429476, "BEVACIZUMAB": 3.3054588069212545, "BORTEZOMIB": 25.32014122752416, "BRAFTOVI": 2.93020532691351, "BUSULFAN": 1.286616037994804, "CAELYX": 4.035874746464884, "CAPECITABINE": 5.283650277506104, "CARFILZOMIB": 4.587445772602574, "CELLCEPT": 1.8285025862711213, "CETUXIMAB": 11.867715054267329, "CYTARABINE": 1.3913158068629603, "DABRAFENIB": 4.975738969265043, "DARZALEX": 13.136839810009102, "DELAMANID": 4.708063363811717, "DEXAMETHASONE": 3.4112238870047693, "DOCETAXEL": 8.982403123324195, "DOLUTEGRAVIR": 27.501523657553747, "FASENRA": 2.126801695656414, "FENTANYL": 1.1465273625664851, "GARDASIL": 1.302949521010892, "HALAVEN": 11.215632563580252, "HERCEPTIN": 3.995612132084032, "INSULIN": 1.2645931689680874, "IPILIMUMAB": 5.290614128625591, "IRINOTECAN": 4.645608137473361, "JAKAVI": 1.690687159859508, "KEYTRUDA": 1.1760914082679477, "LAMIVUDINE": 2.8258993565133608, "LEFLUNOMIDE": 2.538510396295617, "LEVOFLOXACIN": 1.897793573186036, "LYNPARZA": 1.5551196709250397, "MABTHERA": 7.078936670215466, "MEKINIST": 2.351097961791508, "MULTAQ": 2.378831802044324, "NORVIR": 5.739199544723217, "NOXAFIL": 2.94554929983637, "OPDIVO": 1.3773379752262325, "PACLITAXEL": 4.577187379605625, "PANITUMUMAB": 17.62130888824201, "PEGASYS": 1.2215917022518696, "PEGINTRON": 1.2963892279045637, "PEMBROLIZUMAB": 1.7463045744481285, "REYATAZ": 6.777430396939882, "RITUXIMAB": 1.5346126849944344, "ROACTEMRA": 1.0825094978477494, "SHINGRIX": 1.5040554525599985, "SIMPONI": 1.2711301012628589, "TASIGNA": 1.0554234316393625, "THALIDOMIDE": 23.35385164384917, "TWINRIX": 4.828480778267172, "VECTIBIX": 16.7667016003144, "VFEND": 1.3544065922229562, "VORICONAZOLE": 3.3405895687499347, "XELODA": 3.27974274011786, "ZERIT": 58.4463593594333, "ZOSTAVAX": 2.063368375042501}
\ No newline at end of file
+{"ARAVA": 16.75804935473935, "null": 0.2943795592415016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6497.json
index e88077f1dac..1fa6dff8f1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6497.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6497.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 138.43621350133128, "BUSULFAN": 241.51640210653483, "CICLOSPORIN": 77.04412280631654, "MYCOPHENOLATE": 50.36090592134553}
\ No newline at end of file
+{"PEGINTRON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6498.json
index e530e81f3b6..99cf62decc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6498.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6498.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 18.84997598958276, "BASILIXIMAB": 373.9499872182839, "BORTEZOMIB": 72.14547868530732, "CELLCEPT": 204.99569829209383, "CICLOSPORIN": 24.51253409160969, "CIDOFOVIR": 175.93598661295954, "MYCOPHENOLATE": 175.33610809555947, "TACROLIMUS": 70.68430142199296}
\ No newline at end of file
+{"COMIRNATY": 5.20172707626531}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6499.json
index 8b2743e3fbc..5291dc74265 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6499.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6499.json
@@ -1 +1 @@
-{"AIMOVIG": 2.186691439366262, "AMIKACIN": 8.723592742098521, "BUDESONIDE": 4.7789135698057725, "BYETTA": 2.813994962645586, "CLOPIDOGREL": 1.5656732737777417, "COSENTYX": 1.5290353956294114, "ELIQUIS": 5.673721214840196, "ENTYVIO": 2.6332618598522437, "FORSTEO": 1.4934942732004008, "HUMALOG": 1.3054141423518872, "HUMIRA": 3.88680408797094, "JANUVIA": 3.0067486120070237, "MEPOLIZUMAB": 22.05448892182321, "NUCALA": 3.764454420152322, "PEGASYS": 1.4643497404472698, "PLAVIX": 2.2464824514100585, "SIMPONI": 1.152335464427139, "SOMAVERT": 126.81002671235574, "STELARA": 1.5305618876169258, "XELJANZ": 3.879668448788496, "XOLAIR": 2.047137667216888, "null": 2.1031473174941286}
\ No newline at end of file
+{"ANAKINRA": 105.27334704395328, "COMIRNATY": 0.597429747721177, "KYMRIAH": 125.56499856297658, "ROACTEMRA": 38.13068723337594, "null": 0.3994146859466952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/65.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/65.json
index 2fc3c1960e1..34b9fae2588 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/65.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/65.json
@@ -1 +1 @@
-{"MELATONIN": 233.18590181972124}
\ No newline at end of file
+{"COMIRNATY": 6.905039712513494, "SPIKEVAX": 1.5966803504222524, "VAXZEVRIA": 0.1846628783805649, "null": 0.9580789394028736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/650.json
index dd504886fe6..30dc6b7c802 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/650.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/650.json
@@ -1 +1 @@
-{"ADENURIC": 1.1024153165964374, "AERIUS": 1.3846109999942742, "APROVEL": 1.1372812066889804, "AVANDAMET": 2.763557013166295, "AVANDIA": 3.3864220168075776, "BARICITINIB": 11.460978047712834, "BETMIGA": 4.803171294325519, "CANCIDAS": 1.5462032593153747, "COMIRNATY": 2.7896177426539377, "COMPRESSION": 22.92917334070321, "DALIRESP": 3.787587708056783, "DASATINIB": 1.560962510584034, "DELAMANID": 2.039099155055584, "DESLORATADINE": 1.696602160636177, "ELIQUIS": 1.1641240257836516, "EMPAGLIFLOZIN": 2.9462299577937614, "ENTRESTO": 1.8243130293747367, "EVENITY": 2.9160239852004186, "EXFORGE": 3.1963046096998564, "FEBUXOSTAT": 1.1800987461244543, "FORSTEO": 2.429975022402502, "GLIBENCLAMIDE": 1.0680595018592725, "IBUPROFEN": 1.0920080120570697, "IMATINIB": 1.2049059723523992, "JCOVDEN": 5.971439602828725, "KISQALI": 1.0845938721918178, "LIXIANA": 1.1198831824758169, "MANNITOL": 2.8696161635906186, "MEXILETINE": 7.923941572518663, "MICARDIS": 1.2204955970815914, "MIMPARA": 1.4260267557013109, "MULTAQ": 5.199257544728525, "OLANZAPINE": 1.5534343376795152, "OLYSIO": 1.70713462534303, "ONGLYZA": 2.1637002606442524, "OXYBUTYNIN": 1.0978738861637618, "PANTOPRAZOLE": 1.0752352465557031, "PEGFILGRASTIM": 5.632229392640844, "PRADAXA": 1.0915362418940802, "PROPRANOLOL": 1.050672199200812, "RASILEZ": 2.036727684458403, "RELVAR": 4.282954944881019, "RIVAROXABAN": 1.4913258632151112, "SPIKEVAX": 1.6356429058637645, "SPIRONOLACTONE": 1.1844830138324898, "TASIGNA": 1.5112459793956197, "TAXOTERE": 1.3507133490624803, "TERIPARATIDE": 1.3539387954360935, "TIKOSYN": 7.027505058064821, "VALSARTAN": 1.4028763456391111, "VIAGRA": 1.447127081957264, "VIMPAT": 1.670532345151201, "null": 1.1090116675364985}
\ No newline at end of file
+{"null": 0.3414698501099596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6500.json
index ceaabdfe2f9..4e71720b08b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6500.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6500.json
@@ -1 +1 @@
-{"COMBIVIR": 139.53448020130247, "ELIQUIS": 13.864676096176977, "null": 1.028166907891067}
\ No newline at end of file
+{"null": 0.803626107550182}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6501.json
index 2c545d56381..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6501.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6501.json
@@ -1 +1 @@
-{"EYLEA": 1001.2685046105308}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6502.json
index 4a9bbd59ea4..5abd30b7efa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6502.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6502.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4775043595409865}
\ No newline at end of file
+{"AERIUS": 0.6321045152918578, "AIMOVIG": 0.6441898600934437, "AUBAGIO": 0.1320841619557948, "BRILIQUE": 0.3433424707834092, "BRINTELLIX": 0.230865357508352, "CHAMPIX": 0.1495787415828773, "COMBIVIR": 0.319733792824853, "COMIRNATY": 10.969500864047616, "COSENTYX": 0.1206463729876074, "CYMBALTA": 0.0442878815309727, "ELIQUIS": 0.2640270415621381, "ELLAONE": 6.011288323229672, "ESMYA": 5.503489464216597, "EVRA": 13.32914071501503, "GARDASIL": 0.3184917406019645, "KEPPRA": 0.0533212467749664, "KESIMPTA": 0.6382791631364111, "MODERNA": 5.066267212628726, "OCRELIZUMAB": 0.3818361490074602, "PEGASYS": 0.0784103413143018, "PLAVIX": 0.0963972088031581, "RINVOQ": 0.2402261494744091, "RYEQO": 25.013564563326437, "SAXENDA": 0.4917072345437066, "SPIKEVAX": 2.430339405368759, "SPIRONOLACTONE": 1.0889354828943787, "STELARA": 0.1766108718626231, "SUTENT": 0.0268083682094166, "TAMIFLU": 0.5313665970129421, "TOZINAMERAN": 1.1424385569173592, "VAXZEVRIA": 0.5617214392003085, "null": 0.2779804128329267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6503.json
index 1eeca7002af..5773efd7f6c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6503.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6503.json
@@ -1 +1 @@
-{"ABILIFY": 3.5458609860547385, "APIDRA": 1.4131322890239266, "CHAMPIX": 2.662425226860789, "DULOXETINE": 3.708370171811969, "EMPAGLIFLOZIN": 21.63219746544057, "ENTRESTO": 5.092098920893879, "EXFORGE": 1.754956565894496, "EXJADE": 1.3304269908083994, "FORSTEO": 2.596850090387034, "FORXIGA": 34.11144886349959, "HIZENTRA": 1.6475597249338767, "IBUPROFEN": 1.83644537193839, "INSULIN": 2.833298156432316, "JANUMET": 1.1475812172674835, "JANUVIA": 1.0315123913094018, "JARDIANCE": 21.097602727970973, "LANTUS": 1.7347679828734093, "LEVETIRACETAM": 1.117688537795014, "OLANZAPINE": 2.2375607622588274, "OPSUMIT": 1.0906590044877364, "RIBAVIRIN": 2.3949521372821843, "SPINRAZA": 2.795973211520785, "VIREAD": 3.669147609982113, "ZYPREXA": 6.273739608579961, "null": 1.7591772052089862}
\ No newline at end of file
+{"CICLOSPORIN": 1.9979975625713144, "CLOPIDOGREL": 4.183726961089155, "COMIRNATY": 0.3110064251361584, "ICLUSIG": 18.31691825185636, "NILOTINIB": 154.9842544643605, "ROACTEMRA": 5.843876912136647, "TASIGNA": 138.08033710077143, "VAXZEVRIA": 0.2569802504993994, "ZOSTAVAX": 5.159840611297467, "null": 0.8186637000620507}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6504.json
index 2f0009030a9..6dcc7556e0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6504.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6504.json
@@ -1 +1 @@
-{"AIMOVIG": 17.99253239661731, "ATRIPLA": 9.92006364782072}
\ No newline at end of file
+{"null": 2.5880611525333377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6505.json
index a37b081f2d5..aafcd6e02e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6505.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6505.json
@@ -1 +1 @@
-{"ABILIFY": 5.574032999273601, "BUPRENORPHINE": 20.123467965601407, "BUVIDAL": 160.53676347776343, "DEXMEDETOMIDINE": 80.6401665042981, "KEPPRA": 2.5642801201522647, "MIDAZOLAM": 17.71409520889765, "ROTATEQ": 18.78964523807031, "SUBOXONE": 26.64074560396661, "SYNAGIS": 34.438343270752696, "ZYPREXA": 2.818547464676096, "null": 2.351622414669142}
\ No newline at end of file
+{"null": 1.8699619557512364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6506.json
index da887de8939..83d6a3e6283 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6506.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6506.json
@@ -1 +1 @@
-{"COMIRNATY": 5.55088874642594}
\ No newline at end of file
+{"ARAVA": 0.1417208619685753, "CLOPIDOGREL": 2.704417047087622, "COMIRNATY": 0.4381881542934261, "ELIQUIS": 35.646334542825, "ENTRESTO": 1.5130441385536642, "ESBRIET": 1.6335427703802403, "HUMALOG": 0.5930983023299049, "IBRANCE": 0.6208110111037777, "INLYTA": 1.6250887934849598, "KEYTRUDA": 0.5386440981761574, "LANTUS": 0.757091388566223, "LEVOFLOXACIN": 1.1675877212450163, "MACITENTAN": 31.65030092419465, "OLANZAPINE": 0.9087531919428228, "OPSUMIT": 3.5992951421387245, "PLAVIX": 22.000627286243265, "REVATIO": 3.902707183862157, "SPIKEVAX": 0.1897889635251066, "SPRYCEL": 4.192102329831255, "SUTENT": 2.577645981282433, "TOZINAMERAN": 0.3847003227905349, "TRELEGY": 3.236059739155178, "VAXZEVRIA": 0.0970181747202401, "VOTRIENT": 3.032973709693985, "XARELTO": 91.2080853710169, "XELJANZ": 1.295183984664419, "XTANDI": 1.082902870503242, "null": 0.7219097227079275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6507.json
index 8610ec832ab..aedd4b67187 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6507.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6507.json
@@ -1 +1 @@
-{"COMIRNATY": 1.083232527028852, "HUMALOG": 5.702083194997125, "HUMIRA": 2.25676995813038, "LANTUS": 3.076559145535576, "PLAVIX": 2.338066155825059, "VAXZEVRIA": 1.047171785147741, "XTANDI": 1.7995806158307412, "ZYPREXA": 2.746893796203969}
\ No newline at end of file
+{"null": 2.036742456889483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6508.json
index a3702e2d17f..7710079b49b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6508.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6508.json
@@ -1 +1 @@
-{"null": 2.33315261325578}
\ No newline at end of file
+{"null": 2.152693143785813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6509.json
index d6ed06c77b6..6aac0677c1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6509.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6509.json
@@ -1 +1 @@
-{"null": 34.589314240903875}
\ No newline at end of file
+{"EYLEA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/651.json
index 599a977a01c..c079965f928 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/651.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/651.json
@@ -1 +1 @@
-{"null": 1.4515973247004734}
\ No newline at end of file
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6510.json
index e1f3f654395..eab4b13abc4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6510.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6510.json
@@ -1 +1 @@
-{"APIDRA": 4.811088468265711, "FENTANYL": 3.316362977451846, "HUMALOG": 3.0793215704199075, "IBRANCE": 3.111446403852923, "LANTUS": 1.062705761954421, "MMRVAXPRO": 1.449070940704217, "MOVYMIA": 46.00860432469364, "NEVANAC": 88.73316532445071, "ROACTEMRA": 2.235481285835389, "SIMPONI": 6.066648723042844, "STELARA": 4.608336841547685, "null": 3.2184540264612056}
\ No newline at end of file
+{"null": 3.707648156723547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6511.json
index 2a2f6247c9e..a3cbc5c6b09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6511.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6511.json
@@ -1 +1 @@
-{"AIMOVIG": 6.2234132316662025, "ALEMTUZUMAB": 1.179533724734596, "ANAKINRA": 8.115974618438939, "ARIPIPRAZOLE": 1.3337716778868909, "BELIMUMAB": 17.64763999737211, "BENLYSTA": 1.0596051796186978, "BIKTARVY": 1.510134848570921, "BORTEZOMIB": 5.6455309832841865, "BRINTELLIX": 3.938763264138833, "CAPSAICIN": 81.46797197332828, "CHAMPIX": 4.330357210879198, "CIRCADIN": 10.39316768658454, "COSENTYX": 1.0612112328289127, "COVID19": 1.5094098131098614, "CYMBALTA": 1.5012226345749535, "DEXAMETHASONE": 1.1911937912480426, "ENBREL": 1.3812123357983848, "ERENUMAB": 7.247337913942489, "EXFORGE": 1.0895162095616298, "FAMPYRA": 15.788647883684892, "FULVESTRANT": 1.3102777878714316, "GALAFOLD": 11.020034157197278, "GARDASIL": 1.0674003407206138, "IBRANCE": 1.2811908599655335, "INCIVO": 1.0382154830431232, "KAFTRIO": 3.436273604294017, "LATUDA": 2.4843087966396897, "MELATONIN": 8.041967535022787, "MMRVAXPRO": 2.941150128798684, "NOT": 1.4397379542812463, "NUCALA": 1.0391563210120434, "PANTOPRAZOLE": 1.1239971499065002, "PEGINTRON": 1.8364010337434844, "ROTATEQ": 2.753218166522784, "SHINGRIX": 1.673693846300219, "TOZINAMERAN": 1.3373230902446227, "VFEND": 1.7736359646160036, "VORICONAZOLE": 1.5025723654819796, "VORTIOXETINE": 17.93609851102529, "XELJANZ": 1.3476322121261637, "XYREM": 3.1288373834274723, "ZOSTAVAX": 2.739491859186051}
\ No newline at end of file
+{"ABILIFY": 6.726556888253144, "ADENURIC": 47.285773500199184, "COMIRNATY": 0.0619209947436722, "ELIQUIS": 3.5650667179646893, "ENTRESTO": 2.113247653499666, "MULTAQ": 8.62087862811712, "PLAVIX": 2.389022752485175, "VAXZEVRIA": 0.0947024920782875, "VIAGRA": 2.836846714200943, "XTANDI": 1.7351346733694053, "null": 4.048146249363015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6512.json
index b1b2c3625a4..b98058de86d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6512.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6512.json
@@ -1 +1 @@
-{"KEPPRA": 10.847342777148116, "SUBOXONE": 12.63857689910646, "null": 3.654332297223388}
\ No newline at end of file
+{"BRILIQUE": 3.186164338969029, "CLOPIDOGREL": 0.8284290647157677, "COMIRNATY": 0.1487304947600256, "ELIQUIS": 0.7294277304696584, "ENOXAPARIN": 4.368041364572428, "ENTRESTO": 1.6829889292526867, "ESBRIET": 7.822051364246144, "JARDIANCE": 0.9045257666996512, "LYRICA": 1.6074284024783352, "MULTAQ": 4.887511920054617, "OZEMPIC": 19.848292908496667, "PEGASYS": 0.655068291757845, "PLAVIX": 2.6225695016405384, "ROACTEMRA": 2.2927163213332338, "SOLIRIS": 2.174529904158778, "SPIKEVAX": 0.044596841503597, "TOZINAMERAN": 0.3307875568221641, "TRACLEER": 4.734810183627554, "VAXZEVRIA": 0.2888541220418659, "XTANDI": 2.6843084356349656, "null": 4.304983266768736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6513.json
index 1ccadef5448..ba757a705ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6513.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6513.json
@@ -1 +1 @@
-{"ACLASTA": 191.3726483021597, "CINRYZE": 172.09378108364504, "ENTYVIO": 35.361104321313995, "HUMIRA": 9.52025137472416, "INFLIXIMAB": 31.750527756816943, "METHOTREXATE": 6.1303996282856295, "NAGLAZYME": 155.0225596220758, "RITUXIMAB": 15.933221914564468, "RUCONEST": 92.5799569758312, "SOLIRIS": 47.56172966933303}
\ No newline at end of file
+{"ARAVA": 1.6591828596923888, "COMIRNATY": 0.0661062360333424, "ELIQUIS": 3.6033912030624498, "ENTRESTO": 5.142195874885386, "KEPPRA": 1.2735702808132534, "PLAVIX": 3.311740313271792, "VAXZEVRIA": 0.0583051589924729, "null": 6.013069139702176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6514.json
index 14c3cb68c5e..bb7187f26af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6514.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6514.json
@@ -1 +1 @@
-{"SUBOXONE": 76.55170159965064, "null": 1.4241105912350855}
\ No newline at end of file
+{"ADEMPAS": 1.476325543437823, "AERIUS": 0.827033792957532, "AFINITOR": 0.1261286130114458, "ALIMTA": 0.2817900300971502, "AMINOSALICYLIC": 0.2898972548714557, "ANGIOX": 11.86043449487409, "APIXABAN": 0.2935916595887136, "ARANESP": 0.4253353345899883, "ARAVA": 0.0679117444551021, "ARIXTRA": 4.262828652879841, "AVANDIA": 0.1174722795020637, "AVASTIN": 0.5425415858125536, "BENLYSTA": 0.2061996338187698, "BEVACIZUMAB": 0.4988609660106418, "BUMETANIDE": 8.493334721022391, "BYDUREON": 0.2574769591360459, "BYETTA": 0.468775151166023, "CABOMETYX": 0.3730700942088296, "CAPECITABINE": 0.8034453517442256, "CELLCEPT": 0.1578623517476378, "CHAMPIX": 0.207702780019502, "CICLOSPORIN": 0.0811886499510161, "CLOPIDOGREL": 1.746964071335796, "COMIRNATY": 0.0452738594628864, "CUBICIN": 2.549046171444755, "CYMBALTA": 0.7251582028501857, "DASATINIB": 2.079905076942145, "DEXAMETHASONE": 0.3626165302911106, "DULOXETINE": 0.8791742438682232, "ELIQUIS": 1.57127782500176, "ENOXAPARIN": 5.576113313900021, "ENTRESTO": 0.956229367364434, "ERBITUX": 1.5391492615854327, "EXFORGE": 0.3820020598496582, "EXJADE": 0.6536007592662363, "EXVIERA": 2.911021979853384, "FENTANYL": 0.1526914692189313, "FORSTEO": 0.4561882354314155, "FORXIGA": 0.2898327521115172, "IBRANCE": 0.1783304097141692, "IBUPROFEN": 1.3136848647613812, "IRESSA": 0.8517977205316323, "IRINOTECAN": 0.651571820956121, "ISENTRESS": 0.7299442884683867, "JANUMET": 0.2273787174331447, "JANUVIA": 0.4796552963277828, "JARDIANCE": 0.2106697203597185, "KALETRA": 1.6383293374101895, "KEPPRA": 0.2297029608172957, "KETEK": 14.554849425650922, "KEYTRUDA": 0.0727580008367201, "KYMRIAH": 1.1576968427870478, "LEVETIRACETAM": 0.6159365267190873, "LEVOFLOXACIN": 3.104965645030852, "LIXIANA": 2.9090200625299394, "LYRICA": 0.3753040779543942, "MEMANTINE": 2.9070948684615576, "METHOTREXATE": 0.3606360213874891, "MICARDIS": 0.3571593709127056, "MULTAQ": 14.238108353615944, "NEXAVAR": 0.5028555428433052, "NOT": 0.925922467093732, "OLANZAPINE": 0.2610441641480098, "OPSUMIT": 0.7285855976586786, "OSELTAMIVIR": 11.203657936697203, "PANTOPRAZOLE": 1.375872370860662, "PEGASYS": 0.169661685178067, "PLAVIX": 3.9526396276768856, "PRADAXA": 6.653260931743654, "RAPAMUNE": 1.2500367003438906, "REMDESIVIR": 5.886318413113833, "REMICADE": 1.2990927132876875, "REVATIO": 0.9087679620287316, "REVLIMID": 1.6384198958674498, "RIVAROXABAN": 3.965285818107559, "RUBRACA": 0.5802121250329711, "SOLIRIS": 0.2250542867981568, "SORAFENIB": 2.1038195462158686, "SPIKEVAX": 0.0296397417766224, "STELARA": 0.0772492594726854, "STIVARGA": 0.8073734094807806, "SUTENT": 0.3158863025712145, "TAMIFLU": 5.235228137226186, "TARCEVA": 8.283980724673425, "TASIGNA": 0.2315261333598024, "TOZINAMERAN": 0.0975460707830249, "TRACLEER": 2.111860339399548, "VAXZEVRIA": 0.0675533535156001, "VFEND": 0.6466691974375729, "VIAGRA": 0.5366408439584895, "VICTOZA": 0.4390885080750967, "VORICONAZOLE": 1.070414310274285, "VOTRIENT": 0.7309127711447292, "XALKORI": 0.8330613485154431, "XARELTO": 9.560471500323258, "XELEVIA": 23.44174657935997, "XELODA": 4.347527932144155, "XENICAL": 19.50159743590104, "XTANDI": 0.4329050498990796, "ZYPREXA": 0.1864751395885457, "null": 7.641577261356354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6515.json
index acb7768c253..6a3837a2241 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6515.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6515.json
@@ -1 +1 @@
-{"null": 2.039414910660589}
\ No newline at end of file
+{"null": 2.7369647729532067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6516.json
index ba62c5bc8a5..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6516.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6516.json
@@ -1 +1 @@
-{"null": 5.068942649117353}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6517.json
index 476c4c92746..23490b35171 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6517.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6517.json
@@ -1 +1 @@
-{"CICLOSPORIN": 27.488116975361876, "null": 1.0154320630092648}
\ No newline at end of file
+{"null": 1.7100643239240485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6518.json
index 6fb4e4be623..38ad1ebf902 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6518.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6518.json
@@ -1 +1 @@
-{"null": 2.060349732016189}
\ No newline at end of file
+{"ABATACEPT": 0.3122469580549131, "ABRAXANE": 10.92154847537796, "ACTOS": 2.413436957642366, "ADALIMUMAB": 0.0851718116294584, "ADCETRIS": 3.065816015355953, "ADCIRCA": 2.3807064037286896, "ADENURIC": 1.113259977707535, "AFINITOR": 18.38497704141028, "ALECENSA": 19.73846127964552, "ALEMTUZUMAB": 0.4100602282966795, "ALIMTA": 15.30992891974501, "ALL": 1.437288589496275, "ALOXI": 6.442653242552805, "ALPELISIB": 1.4406786922692931, "ANAKINRA": 5.862265891162632, "APROVEL": 1.8812055000333452, "ARAVA": 0.889131183550665, "ASPARAGINASE": 0.2439870540765558, "AUBAGIO": 0.3182249497412848, "AVASTIN": 8.203222251126874, "AXITINIB": 1.6303704694596357, "AZACITIDINE": 0.3868375478205892, "AZATHIOPRINE": 2.4904506559526896, "BARACLUDE": 1.36750612188959, "BAVENCIO": 1.4671679540837483, "BEDAQUILINE": 0.4641020763805361, "BENLYSTA": 0.1447610678700125, "BEVACIZUMAB": 2.375327793040459, "BOSULIF": 0.7510732158478859, "BRAFTOVI": 2.257630343041064, "BRILIQUE": 0.3875123013433868, "BUMETANIDE": 3.851261225899821, "BUSULFAN": 1.439363797584917, "CABOMETYX": 3.472650526694036, "CAELYX": 14.952238530596354, "CANCIDAS": 1.851063246063832, "CAPECITABINE": 0.555127323334428, "CARMUSTINE": 0.6638240997032365, "CELECOXIB": 0.847660274022403, "CELLCEPT": 2.110211422993723, "CETUXIMAB": 5.76264336238349, "CICLOSPORIN": 1.0438583403561434, "CIMZIA": 1.1239772377725128, "CLADRIBINE": 0.9130761519348792, "CLOPIDOGREL": 0.4677175916336758, "COAPROVEL": 2.086469001674572, "COMIRNATY": 0.0510214750103788, "COSENTYX": 0.377269090030777, "COTELLIC": 1.1052598103727804, "CUBICIN": 5.298761139421984, "CYMBALTA": 0.1463864727927856, "CYRAMZA": 23.18550861369721, "CYTARABINE": 0.4633465565523846, "DABRAFENIB": 0.5870667016916382, "DARZALEX": 1.2643805783608644, "DASATINIB": 0.9473168574365496, "DESLORATADINE": 0.9203192535164526, "DEXAMETHASONE": 0.5715109992294922, "DOCETAXEL": 4.069747627390993, "DOXORUBICIN": 7.142306990121552, "DULOXETINE": 0.4871642481370754, "EFIENT": 1.0170161477057214, 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0.8011229794007106, "HERCEPTIN": 6.659204131341141, "HUMAN": 0.6415766193879039, "HUMIRA": 0.9388420178033742, "HYCAMTIN": 5.31336863781602, "IBRANCE": 1.386660999769798, "IBUPROFEN": 0.1197254699352469, "ICLUSIG": 0.7739490639315494, "IMFINZI": 28.94273436018254, "IMNOVID": 4.273957163611622, "INCIVO": 0.2200894066892, "INFLIXIMAB": 2.5614844002876835, "INLYTA": 1.5467229544972103, "INTRONA": 4.567996500738476, "IPILIMUMAB": 0.9058376162133126, "IRESSA": 76.98093674836446, "IRINOTECAN": 2.6588924243645606, "JAKAVI": 1.1058958621555537, "JANUMET": 0.2286313204882145, "JANUVIA": 3.407923210034577, "JARDIANCE": 0.123508567683019, "JEVTANA": 6.140435186089639, "KEPPRA": 0.1098746642965899, "KEYTRUDA": 20.563046350478697, "KISQALI": 1.641973648685077, "KYPROLIS": 2.255682987423362, "LANTUS": 0.0513169932840337, "LEFLUNOMIDE": 1.3330508376504626, "LEMTRADA": 0.2233481838269256, "LENVIMA": 4.972714864401161, "LEVETIRACETAM": 0.2098577062183413, "LEVOFLOXACIN": 0.7202067171705734, "LIBTAYO": 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"XOLAIR": 0.0924027433250721, "XTANDI": 0.8191483702036945, "YERVOY": 0.6010333734792627, "ZYPREXA": 0.09669501828484, "null": 0.9245717124302378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6519.json
index 3eef8b30ef7..3ab428e7301 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6519.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6519.json
@@ -1 +1 @@
-{"ADALIMUMAB": 5.591640668937998, "DEXMEDETOMIDINE": 273.6694587616796, "null": 1.9708563105913453}
\ No newline at end of file
+{"BIKTARVY": 195.03934183053948, "JARDIANCE": 10.217527028901626, "null": 0.5396535701018487}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/652.json
index 27dd89172de..cd6b49cdae7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/652.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/652.json
@@ -1 +1 @@
-{"ELIQUIS": 1.6431209173928865, "null": 1.3023686916356072}
\ No newline at end of file
+{"null": 0.7127343957588432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6520.json
index dfd9a12e49d..f6e1f69cc63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6520.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6520.json
@@ -1 +1 @@
-{"PEGASYS": 16.16536088612806, "PEGINTERFERON": 41.67349272695679, "RIBAVIRIN": 28.203000947941906}
\ No newline at end of file
+{"ARAVA": 14.617628565949436, "null": 0.5612154634013213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6521.json
index ad3e6ba9a7d..ae13e6a8a25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6521.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6521.json
@@ -1 +1 @@
-{"null": 1.2326483963287242}
\ No newline at end of file
+{"ALENDRONATE": 184.7584371140261, "APIXABAN": 13.773525420094185, "ARAVA": 0.258400667776899, "ATRIPLA": 16.00125659303533, "AUBAGIO": 0.9963009704843024, "BIKTARVY": 2.508563819178304, "BUPIVACAINE": 6.856659515240994, "BUPRENORPHINE": 2.660208236170796, "BYETTA": 4.3980560705519895, "CIMZIA": 0.5286022397655433, "COMIRNATY": 0.0508598839237914, "COSENTYX": 2.2866973093656613, "CYMBALTA": 0.9029441368050044, "DULOXETINE": 5.036549041447541, "ELIQUIS": 1.5193279563215707, "ENBREL": 1.7435421951369068, "EVISTA": 6.545048288501292, "FENTANYL": 0.90002052344607, "GARDASIL": 0.8691283511297629, "HUMALOG": 2.248631085804534, "IBRANCE": 0.6127072980085115, "IBUPROFEN": 1.921640510209765, "JANUMET": 3.0223991721408128, "JANUVIA": 2.559528055596142, "KEPPRA": 0.5769845656663646, "KEYTRUDA": 0.4194528894680441, "LANTUS": 0.8790074367308973, "LYRICA": 3.2875249321616296, "METHOTREXATE": 2.22926714080512, "PEGINTRON": 0.791083798960518, "SIMPONI": 1.093477616084337, "SPIKEVAX": 0.1167794025901121, "STRIBILD": 6.914664223853307, "SUBOXONE": 2.796652675646357, "SUTENT": 0.3246296958376713, "TASIGNA": 2.5137973753781053, "TOZINAMERAN": 0.1556842089536337, "TRUVADA": 6.447042394555401, "VAXZEVRIA": 0.029559807284844, "VIAGRA": 2.516620130317171, "VIREAD": 3.236502444989977, "XELJANZ": 2.40146723515131, "XYREM": 5.197283268681771, "ZOSTAVAX": 10.702295146039871, "null": 0.6566666778854763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6522.json
index 3bad4ba6b9b..42a8032f307 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6522.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6522.json
@@ -1 +1 @@
-{"ADCIRCA": 493.2699308308524}
\ No newline at end of file
+{"ATRIPLA": 1.5867518942956875, "BOSULIF": 16.77667193430694, "COMIRNATY": 0.2796563038807358, "ELIQUIS": 1.1178353362722702, "ENBREL": 12.60873720505488, "ESOMEPRAZOLE": 12.920828820535943, "HUMALOG": 1.541168220480374, "HUMIRA": 3.105880443365572, "IBUPROFEN": 4.606975019570369, "LANTUS": 2.3255915458252674, "LYRICA": 4.946355547623246, "SIMPONI": 1.863876564253075, "SPIKEVAX": 0.1625126583191532, "STELARA": 1.4837060251337313, "SUBOXONE": 3.106924135520205, "SUTENT": 1.2335849510663084, "TIVICAY": 25.18928080442944, "TOZINAMERAN": 0.3761098814795958, "TRUVADA": 1.4734838212567614, "VAXZEVRIA": 0.0613433985125842, "VIAGRA": 4.108976633062696, "XELJANZ": 2.6808684956244457, "ZOSTAVAX": 8.803229773181984, "null": 1.0571443977279793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6523.json
index 8be8b9e76e9..23d9f3058d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6523.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6523.json
@@ -1 +1 @@
-{"ABACAVIR": 4.956103283268751, "AVASTIN": 11.640929385326508, "AZATHIOPRINE": 4.706648151379506, "BEVACIZUMAB": 16.905831135172203, "BYETTA": 3.736345191910292, "CAPECITABINE": 7.229159722415427, "EFAVIRENZ": 17.512074404453557, "EMTRICITABINE": 19.21823019636772, "EMTRIVA": 54.101806259511264, "EPIVIR": 18.97363116246328, "IRINOTECAN": 9.869382948144722, "JAKAVI": 5.502912316308954, "KAFTRIO": 10.467773024288835, "KALETRA": 4.433366126230136, "LAMIVUDINE": 19.0316419296194, "NEXAVAR": 2.409117571334489, "NPLATE": 6.3400550753037965, "OCALIVA": 23.18355387462372, "OPSUMIT": 4.102645259013127, "PEGASYS": 5.313027487976421, "PEGINTRON": 1.6392574317879016, "RIBAVIRIN": 8.161965845362309, "SOLIRIS": 4.200131786818342, "STIVARGA": 3.245864818011414}
\ No newline at end of file
+{"null": 0.8016876378115404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6524.json
index 8c94f00272f..d0510599936 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6524.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6524.json
@@ -1 +1 @@
-{"ADCIRCA": 190.1001047735297, "OPSUMIT": 15.664425126822003}
\ No newline at end of file
+{"null": 1.0750198134476086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6525.json
index 9a16be6e787..df2fed07464 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6525.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6525.json
@@ -1 +1 @@
-{"ADCIRCA": 435.214280130478, "null": 1.319335982684351}
\ No newline at end of file
+{"SIMPONI": 14.707250236047395, "null": 1.0663526010132711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6526.json
index 4314ffa2c64..70701dcf7e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6526.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6526.json
@@ -1 +1 @@
-{"null": 1.016791246989776}
\ No newline at end of file
+{"ADALIMUMAB": 0.6521968354446657, "AIMOVIG": 0.9710618777949372, "APIDRA": 1.433813238006815, "ARAVA": 0.656957282715049, "ATRIPLA": 2.1685607716856103, "AUBAGIO": 3.79442772916001, "BENLYSTA": 2.167926738944617, "BENRALIZUMAB": 64.2737592316961, "BUPRENORPHINE": 1.351148101097052, "BUSULFAN": 3.252380782849349, "BYETTA": 1.9483304195747757, "CANNABIDIOL": 18.95311135418196, "CELLCEPT": 0.7355770481606494, "CHAMPIX": 0.4815791861514774, "CIMZIA": 0.9597367173045624, "COMIRNATY": 0.3112834808269694, "COSENTYX": 1.1495942847164695, "CYMBALTA": 1.444668756947547, "DEXAMETHASONE": 0.6394618049945192, "ELIQUIS": 1.0580900888887446, "ENBREL": 3.0587858059283097, "EXFORGE": 3.2890801210137166, "FAMPYRA": 3.758136549012384, "FASLODEX": 1.859685402604769, "FENTANYL": 1.4441335028766713, "FORSTEO": 2.876095986875926, "GARDASIL": 1.1463699748679466, "HUMALOG": 2.973876968609263, "HUMIRA": 5.97128951855531, "IBRANCE": 0.8785158380785792, "IBUPROFEN": 2.263177869068653, "JAKAVI": 1.5110163010498303, "JANUMET": 1.2701989158270153, "JANUVIA": 0.678679058975152, "KEPPRA": 0.5468224116448095, "KEYTRUDA": 0.3030371482956364, "LANTUS": 3.461171331460984, "LEVEMIR": 2.1366960269370567, "LEVOFLOXACIN": 0.597833484680912, "LYRICA": 9.01506107978662, "MEPOLIZUMAB": 0.9660300546950632, "METHOTREXATE": 0.6693863355330602, "OPTIMARK": 0.8983866833091365, "ORENCIA": 16.170544142926982, "OZEMPIC": 16.122839969193087, "PEGASYS": 0.6771715905846901, "PLAVIX": 0.7379959043294648, "REVATIO": 2.721554729845801, "RINVOQ": 2.7781580923787472, "SIMPONI": 4.108422811261697, "SPIKEVAX": 0.1564650924536377, "STELARA": 1.464802594388088, "STRIBILD": 1.6730284104570328, "SUBOXONE": 3.641716992925165, "SUTENT": 0.4900003248702964, "TASIGNA": 2.01136342106698, "TOZINAMERAN": 0.2677694546822322, "TRUVADA": 1.7221467460758286, "VAXZEVRIA": 0.0792929964868249, "VIAGRA": 5.250956694623164, "XELJANZ": 3.769788022619701, "XOLAIR": 1.0427626536750576, "XYREM": 7.969155623542485, "ZOSTAVAX": 4.432547223052121, "null": 1.011300568310666}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6527.json
index 451d3ba3d97..cae4700003d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6527.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6527.json
@@ -1 +1 @@
-{"AVASTIN": 7.608930707820455, "BEVACIZUMAB": 8.682007320946147, "CABOMETYX": 4.838309795451629, "COVID19": 1.664626266788663, "ESOMEPRAZOLE": 6.199317682575309, "EXVIERA": 18.7773343372558, "HARVONI": 9.431582628508904, "INCIVO": 3.664772253673176, "JAKAVI": 7.406106254026403, "JANUMET": 1.8945496121228984, "JANUVIA": 2.159127344941448, "LENVIMA": 16.95733373696746, "NEXAVAR": 10.14030283768059, "NOVOSEVEN": 34.18865079316216, "NPLATE": 9.267955716133097, "OLYSIO": 16.432735008781343, "PEGASYS": 1.2763448634717611, "PEGINTRON": 2.114847633981307, "RIBAVIRIN": 11.541880933481238, "RINVOQ": 4.602849813601846, "SOLIRIS": 5.939272258552816, "SOVALDI": 15.421635932283817, "TESTOSTERONE": 23.015678258440865, "VAXZEVRIA": 2.553698747838306}
\ No newline at end of file
+{"ARAVA": 20.580049347749675, "ATRIPLA": 2.879094128470016, "TRUVADA": 5.99790697712559, "null": 0.2070215725994163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6528.json
index bd87dba97e4..3aea2ab3c40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6528.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6528.json
@@ -1 +1 @@
-{"DOCETAXEL": 56.987472475308735, "null": 1.7476688258902946}
\ No newline at end of file
+{"CICLOSPORIN": 2.973481173427809, "CIMZIA": 2.368370648238561, "COMIRNATY": 0.3348304086084917, "CUBICIN": 21.184428349468572, "PEGINTRON": 5.502203486851474, "ROACTEMRA": 23.95114763621588, "STELARA": 4.0720775130630775, "null": 0.7873772013733333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6529.json
index 033965b801f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6529.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6529.json
@@ -1 +1 @@
-{"COMIRNATY": 1.697062603765418, "COVID19": 1.8574624691481685, "VAXZEVRIA": 6.315673624353204}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/653.json
index e86348a93a4..04df4456f60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/653.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/653.json
@@ -1 +1 @@
-{"ENTRESTO": 20.15894567754527, "MEXILETINE": 2550.613125453545, "null": 1.358970350655756}
\ No newline at end of file
+{"null": 0.7256991417055473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6530.json
index a9df16a39e8..49c28b7afc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6530.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6530.json
@@ -1 +1 @@
-{"SPIKEVAX": 4.225397257192262}
\ No newline at end of file
+{"HUMIRA": 53.22351986680141, "ROTATEQ": 100.94140798348938, "null": 0.2558298307316865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6531.json
index c5f32186c41..195e3dc129a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6531.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6531.json
@@ -1 +1 @@
-{"null": 17.481807052488172}
\ No newline at end of file
+{"null": 20.685311882779843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6532.json
index 36d359c3245..96119ecc62a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6532.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6532.json
@@ -1 +1 @@
-{"null": 1.2750659248573155}
\ No newline at end of file
+{"null": 2.18291737345322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6533.json
index 81df261923c..8ee68b3f55d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6533.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6533.json
@@ -1 +1 @@
-{"null": 1.321596290799513}
\ No newline at end of file
+{"BRIVARACETAM": 1301.3554673539454, "null": 0.8740741756598425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6534.json
index fa615f4e8c8..f937c2adb16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6534.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6534.json
@@ -1 +1 @@
-{"null": 4.038627971753013}
\ No newline at end of file
+{"COMIRNATY": 5.181421943665497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6535.json
index ecb5cc8683b..6f40b7de540 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6535.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6535.json
@@ -1 +1 @@
-{"JAKAVI": 2.260889048951999, "LYRICA": 6.390019563471146, "NOT": 9.798881532023334, "RINVOQ": 3.496675873382596, "SHINGRIX": 44.72816960934562, "XELJANZ": 1.1578149547089918, "ZOSTAVAX": 329.024380833753}
\ No newline at end of file
+{"null": 1.5854446637012745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6536.json
index c78bc13c275..d9a0d98eab1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6536.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6536.json
@@ -1 +1 @@
-{"OPTIMARK": 43.121424622012185, "ZOSTAVAX": 14.020808157928386}
\ No newline at end of file
+{"null": 0.3722926360196361}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6537.json
index 57c27e29443..c8f3747bd5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6537.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6537.json
@@ -1 +1 @@
-{"FENTANYL": 6.156961969546647, "GARDASIL": 1.9854357365500932, "SPINRAZA": 6081.1811400013785}
\ No newline at end of file
+{"null": 10.36117198542795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6538.json
index 1c9f23c9c85..dcde4dbf89b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6538.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6538.json
@@ -1 +1 @@
-{"AZILECT": 1595.9617023553117, "TOVIAZ": 133.10271977977422, "null": 1.8595273061289463}
\ No newline at end of file
+{"COMIRNATY": 0.1104471495839131, "ZYPREXA": 4.208933860377842, "null": 1.650116648601822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6539.json
index fc65173367a..dc510103358 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6539.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6539.json
@@ -1 +1 @@
-{"null": 1.3201499688026834}
\ No newline at end of file
+{"ENTYVIO": 31.491377562337632, "KEYTRUDA": 8.197555565264095, "SUTENT": 5.005842009498007, "null": 0.2790243859827835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/654.json
index 61f3aa553f4..1a033b9f524 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/654.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/654.json
@@ -1 +1 @@
-{"null": 1.280142941968354}
\ No newline at end of file
+{"AVANDIA": 4.333558304004541, "BUDESONIDE": 4.8402087400015725, "CELLCEPT": 2.2840334784553864, "CICLOSPORIN": 0.7608429492725424, "CLOPIDOGREL": 2.542832646766422, "COMIRNATY": 0.4849517504578114, "ELIQUIS": 1.9360101566605925, "FORSTEO": 1.1934233664430507, "GARDASIL": 3.550093183006948, "HUMALOG": 2.9590635681604693, "HYDROCORTISONE": 9.142110937224588, "ICLUSIG": 9.050060055837887, "LANTUS": 3.0126645323533814, "MIMPARA": 10.238481164956204, "PEGINTRON": 1.918830551663541, "PLAVIX": 3.7639530705298143, "SPIKEVAX": 0.1475732503773175, "SUTENT": 0.6799221245005708, "TASIGNA": 8.541266759506541, "TOZINAMERAN": 0.507950327618545, "VAXZEVRIA": 0.1930622251538491, "VIAGRA": 5.424495460314242, "ZOSTAVAX": 1.0454582909096233, "null": 1.209392445827005}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6540.json
index 5db7ce49da6..f4da1dbd767 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6540.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6540.json
@@ -1 +1 @@
-{"AUBAGIO": 1.253005002912683, "CIMZIA": 1.816438828054135, "ELIQUIS": 1.9752790709945875, "ENBREL": 3.444012119654817, "EXJADE": 2.508990298476559, "FENTANYL": 9.0085269394889, "FORSTEO": 2.792260712174081, "HUMALOG": 4.741386534633255, "HUMAN": 5.889679632824693, "HUMIRA": 2.323409032475936, "INSULIN": 2.3076596515599186, "JANUMET": 1.487004053552518, "JANUVIA": 2.063094705788182, "JARDIANCE": 4.688576365666854, "LANTUS": 1.6326644777654655, "NPLATE": 3.8925661779645377, "NUCALA": 1.2179255166318457, "OFEV": 2.691475955140743, "OMALIZUMAB": 3.278814282345127, "OPSUMIT": 1.4276553560112797, "RINVOQ": 2.96557265258614, "SIMPONI": 2.14598878252412, "SPINRAZA": 57.565698813811885, "STELARA": 1.8364803751954035, "SUTENT": 1.3661891974500735, "TRACLEER": 4.00504605451263, "TRELEGY": 2.383922209404938, "TREMFYA": 4.92119354707447, "XELJANZ": 4.0430533651762, "XOLAIR": 1.030742597973045, "ZYPADHERA": 88.53570773576514, "null": 1.0519573183617956}
\ No newline at end of file
+{"null": 1.1511229020506544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6541.json
index 83f8b14bca7..623e5d1c5cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6541.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6541.json
@@ -1 +1 @@
-{"ANAKINRA": 149.62107970785385}
\ No newline at end of file
+{"CLOPIDOGREL": 10.419682563016115, "null": 4.880978592334923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6542.json
index 6ac5d3e5c05..760d1127b43 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6542.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6542.json
@@ -1 +1 @@
-{"null": 1.000143026188907}
\ No newline at end of file
+{"APIDRA": 3.230927868661144, "BRILIQUE": 21.03161312581302, "BRINTELLIX": 1.956568388491105, "CICLOSPORIN": 0.87383131603043, "CIMZIA": 0.621889593451101, "CLOPIDOGREL": 7.580805157289242, "COMIRNATY": 0.2977130711893814, "COSENTYX": 1.5210236044677892, "CYMBALTA": 0.43976588358238, "EFIENT": 19.750451417370893, "ELIQUIS": 13.461621957996655, "KEYTRUDA": 0.5521769961036191, "LANTUS": 0.4530783253640577, "LIXIANA": 50.37330192525222, "MEPOLIZUMAB": 5.832219902546267, "NEXAVAR": 1.8722276635941943, "NOXAFIL": 13.06149933180976, "PEGASYS": 0.4387952593352522, "PLAVIX": 8.896400531193333, "ROACTEMRA": 2.283686533977654, "SIMPONI": 1.7038940049918865, "SPIKEVAX": 0.0939496748422338, "SPRYCEL": 2.676908134644101, "STIVARGA": 5.545258221650082, "SUTENT": 2.587177589311766, "VAXZEVRIA": 0.1498965989473273, "VOTRIENT": 1.843249362778289, "XARELTO": 4.10846404499321, "XELJANZ": 0.9956132473241204, "null": 1.0442063301006437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6543.json
index 6592921ce1f..e0e8253842e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6543.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6543.json
@@ -1 +1 @@
-{"SPINRAZA": 204.8236967187005}
\ No newline at end of file
+{"COMIRNATY": 0.4000304428912656, "VAXZEVRIA": 0.5273168215921386, "null": 1.078399051530331}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6544.json
index 1f996dc143e..24d4baa4535 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6544.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6544.json
@@ -1 +1 @@
-{"BRILIQUE": 12.544621739624002, "CLOPIDOGREL": 9.270539631213488, "ELIQUIS": 14.607861096484418, "PLAVIX": 15.375998685287408, "SPINRAZA": 19.88214714778649, "null": 1.5321016464388484}
\ No newline at end of file
+{"null": 5.0267454307815465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6545.json
index 31c2412a175..92b69dd690b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6545.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6545.json
@@ -1 +1 @@
-{"ELIQUIS": 32.98303914682567}
\ No newline at end of file
+{"ARAVA": 0.824534452208432, "AVANDIA": 1.2006435029764448, "AVASTIN": 2.964208542346468, "CELLCEPT": 2.2670350330854023, "CLOPIDOGREL": 2.2445064718409826, "COMIRNATY": 0.4036019758686814, "ELIQUIS": 1.154330806353676, "KEYTRUDA": 1.1200141520355638, "LEVETIRACETAM": 2.0691279262923548, "NEXAVAR": 1.065603737271715, "NOVOSEVEN": 38.035769153883145, "OLANZAPINE": 1.4218164935768902, "PEGASYS": 1.3337408813804483, "PLAVIX": 0.9835318279280636, "ROACTEMRA": 3.0772145372945947, "SOLIRIS": 1.856125177998086, "SPIKEVAX": 0.1692096726920306, "SUTENT": 1.0996512540563237, "TRACLEER": 2.097674721476978, "VAXZEVRIA": 0.5393956241150332, "null": 1.4442759933271254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6546.json
index ec412e59b01..fd4be36011e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6546.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6546.json
@@ -1 +1 @@
-{"ANGIOX": 34.2588339284578, "BRIDION": 8.741206586779095, "BRILIQUE": 11.321105043922062, "CABOMETYX": 1.9097212863427808, "CELLCEPT": 1.0258687793050076, "CLOPIDOGREL": 13.04822598588826, "ELIQUIS": 24.00538431564614, "ENOXAPARIN": 9.704654856953672, "FENTANYL": 1.2880853295435046, "FIRDAPSE": 4.867379872549266, "HEMLIBRA": 26.97633434903145, "JAKAVI": 4.508040879506992, "LEVEMIR": 2.0661060150427715, "LIXIANA": 11.79132078421702, "MACITENTAN": 25.313683515697647, "MIDAZOLAM": 2.40358989308267, "NOVOSEVEN": 18.917217920078333, "OCTREOTIDE": 40.42174416181631, "PLAVIX": 22.005186251289697, "SOLIRIS": 4.40645166568044, "SPINRAZA": 7.181089276620807, "TICAGRELOR": 5.864217060738054, "XARELTO": 15.694598329229065, "null": 1.552914597503994}
\ No newline at end of file
+{"null": 1.5312395412331168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6547.json
index a55efd4bf15..4ac0dd2c56d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6547.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6547.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 36.44921523683357}
\ No newline at end of file
+{"null": 0.7090211814480226}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6548.json
index 6100003a7c2..26eda793bd3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6548.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6548.json
@@ -1 +1 @@
-{"BYETTA": 241.0856269030708, "EFAVIRENZ": 232.15547212950776}
\ No newline at end of file
+{"null": 2.4251615483088984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6549.json
index 3d1bd8bb796..f7f48fc6745 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6549.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6549.json
@@ -1 +1 @@
-{"BEXTRA": 129.32191508716056, "BYETTA": 3.6446276271560185, "CICLOSPORIN": 1.185990197458049, "CIMZIA": 2.994667647337176, "COSENTYX": 3.4569787862136243, "ELIQUIS": 2.4896543912600486, "ENBREL": 4.211825732761012, "FORSTEO": 2.870297609602072, "HUMALOG": 3.6401411605545406, "HUMIRA": 8.60113055895309, "HYDROCORTISONE": 10.70054335585496, "IBRANCE": 1.2386663749406108, "JARDIANCE": 2.5003885749015864, "LANTUS": 1.094185620774858, "RINVOQ": 5.919483272612193, "SIMPONI": 12.204378354764938, "SPINRAZA": 23.51661666310653, "XELJANZ": 9.684732945782804, "null": 1.0045879689808908}
\ No newline at end of file
+{"AFINITOR": 18.588389484632984, "BYETTA": 19.22185324912504, "CABOMETYX": 28.611981514126622, "FASLODEX": 31.54858814547517, "JANUMET": 20.111167396698168, "MEKINIST": 21.677508070145265, "null": 0.3520671893194094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/655.json
index 78ab3f890d7..9f6e5671f05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/655.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/655.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 7.441972642488024, "AVANDIA": 7.327198674532172, "CICLOSPORIN": 7.349033329217061, "ELIQUIS": 2.2091494959624507, "HUMALOG": 2.588967014562717, "JANUMET": 17.337857514953527, "PLAVIX": 2.1811583509497425, "SUTENT": 1.2946334154054504, "TASIGNA": 42.12464685714461}
\ No newline at end of file
+{"AVANDAMET": 45.84325643231059, "AVANDIA": 25.75840700252757, "CLOPIDOGREL": 4.126633324446446, "INFLIXIMAB": 39.68660109588753, "JANUMET": 11.776955572525369, "JANUVIA": 7.077460816221555, "LANTUS": 3.134459951723984, "OPSUMIT": 6.683211649594256, "PLAVIX": 3.645227226938779, "TRACLEER": 8.806714440816204, "null": 1.1360927511606538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6550.json
index f3ab8954a19..bf67e53c9cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6550.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6550.json
@@ -1 +1 @@
-{"SPINRAZA": 107.72222377474203}
\ No newline at end of file
+{"null": 3.7738708059543176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6551.json
index 908c1f05648..ee1a527352f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6551.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6551.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 85.15263786883847, "AZATHIOPRINE": 18.139088290645475, "BASILIXIMAB": 55.8031209991636, "BUSILVEX": 71.99214415824973, "BUSULFAN": 51.63142090930607, "CAELYX": 20.86388934609301, "CARMUSTINE": 32.85664997954095, "CELLCEPT": 74.24318279991152, "CICLOSPORIN": 114.75031611108524, "CYTARABINE": 3.5347068757922746, "DINUTUXIMAB": 95.8295562186226, "GANCICLOVIR": 27.977122528355924, "METHOTREXATE": 4.8697238023389415, "MYCOPHENOLATE": 67.84965207266681, "RAPAMUNE": 9.425074859114725, "RITUXIMAB": 6.6189281996480895, "TACROLIMUS": 23.09285420269395}
\ No newline at end of file
+{"null": 1.9341756838760509}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6552.json
index 2b88e3b4019..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6552.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6552.json
@@ -1 +1 @@
-{"COMIRNATY": 13.416230219233356, "GARDASIL": 3.322719634718234, "SPIKEVAX": 2.5608776459681635, "VAXZEVRIA": 1.5357375396827433}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6553.json
index 32d398784b4..b8ef2d14bdb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6553.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6553.json
@@ -1 +1 @@
-{"COMIRNATY": 8.180331892970766, "SPIKEVAX": 2.245101233871936, "TOZINAMERAN": 1.78625286337166, "VAXZEVRIA": 1.764450727966624}
\ No newline at end of file
+{"ABILIFY": 2.3357864216059583, "AFINITOR": 3.316888197367843, "AIMOVIG": 4.31461646963416, "ALIMTA": 0.971154342358391, "AMINOSALICYLIC": 1.0975771959739489, "ARAVA": 1.036319556312986, "ARIPIPRAZOLE": 1.4897152406983103, "ARZERRA": 19.9927447730106, "AUBAGIO": 0.4805719643386044, "AVASTIN": 8.3249934220319, "BEDAQUILINE": 1.6187399471008932, "BENLYSTA": 0.5733096401379814, "BEVACIZUMAB": 3.328759772854729, "BRAFTOVI": 5.950092364101555, "BUDESONIDE": 0.2512081560169266, "BUPRENORPHINE": 1.2213499914144317, "BUSULFAN": 0.8616475155723757, "BYDUREON": 0.7866271335829933, "BYETTA": 0.8136828313067109, "CABOMETYX": 1.1492571925188806, "CAELYX": 4.048924344642032, "CAPECITABINE": 1.306684941124168, "CELLCEPT": 1.0452592863441266, "CHAMPIX": 0.3814450862613387, "CICLOSPORIN": 0.5080485317579189, "CIMZIA": 3.2275841518088275, "CLOPIDOGREL": 0.3841390352443212, "COMIRNATY": 0.0725588963033485, "COTELLIC": 3.0566396679970795, "CYMBALTA": 0.9004779119180139, "CYTARABINE": 1.5138618585134092, "DEXAMETHASONE": 0.7599225200921115, "DOCETAXEL": 2.520114377391215, "ELIQUIS": 0.8332098719101877, "EMEND": 3.75917015407998, "ENBREL": 0.2759062309363913, "ENTYVIO": 9.282704403497831, "ERBITUX": 3.825345488288227, "ESBRIET": 1.239891616751327, "EXJADE": 0.7590012836679106, "FASLODEX": 0.5256673011799627, "FENTANYL": 0.8158314634922033, "FIRDAPSE": 2.586779812852288, "FORSTEO": 2.6225883692580148, "HIZENTRA": 2.313789420157242, "HUMALOG": 0.4222290358825536, "HUMIRA": 2.10671271446557, "IBRANCE": 1.725830519848491, "INCRUSE": 2.5006485524496425, "INFLIXIMAB": 6.1868306263258, "INLYTA": 0.9495224387331884, "IRESSA": 2.2174715403769296, "IRINOTECAN": 2.811664417113687, "JAKAVI": 1.3184591139997812, "JANUMET": 1.485454375818076, "JANUVIA": 3.330267841869171, "JARDIANCE": 0.7934144746726952, "KAFTRIO": 2.664130479155897, "KALYDECO": 5.374002224770848, "KEPPRA": 0.5518984186571767, "KEYTRUDA": 1.5238844263048188, "LANTUS": 0.491995025657293, "LONSURF": 9.856655872826012, "LUTATHERA": 11.951299568734497, "LYNPARZA": 4.633413372442902, "LYRICA": 0.9103539947066008, "MEKINIST": 1.1310998011265023, "MEPOLIZUMAB": 0.7849285726777575, "MVASI": 13.719040317628911, "NEULASTA": 1.051716396757198, "NEXAVAR": 0.3947332284043505, "OFEV": 1.7208292706694075, "OLANZAPINE": 2.750325978806978, "OMALIZUMAB": 0.5043576089756672, "OPDIVO": 0.6139744270314067, "OPSUMIT": 1.439266236902092, "ORKAMBI": 12.892589610542563, "PANTOPRAZOLE": 1.0679062438284015, "PEGASYS": 0.8479055495257976, "PLAVIX": 0.5935550318609689, "RAPAMUNE": 1.907127116936253, "REMICADE": 3.091521165483192, "REVATIO": 1.0530758741393056, "REVESTIVE": 22.70720852555464, "ROTASHIELD": 551.3179136022165, "ROTATEQ": 3.372379828043359, "RUBRACA": 15.398804757094736, "RYBELSUS": 3.58882191137151, "SAXENDA": 2.91422178720769, "SIFROL": 3.372427046127813, "SIMPONI": 0.5692695232316761, "SKYRIZI": 4.3474030201401, "SOLIRIS": 1.1364382633022143, "SPIKEVAX": 0.0682921319215138, "STELARA": 6.50935217905369, "STIVARGA": 3.6023502676312416, "SUBOXONE": 0.646299426200919, "SUTENT": 2.119258543409182, "TAMIFLU": 0.6648450065928215, "TEDUGLUTIDE": 48.92497417169078, "TOVIAZ": 2.8572165296643317, "TOZINAMERAN": 0.0897276003270203, "TRACLEER": 1.0633590527801275, "TREMFYA": 1.4902415219615932, "TRULICITY": 3.9566961672398295, "VAXZEVRIA": 0.0429997176080705, "VEDOLIZUMAB": 13.852601989038355, "VELTASSA": 2.419053203659203, "VFEND": 1.0433181988361206, "VICTOZA": 3.9604484171539744, "VIMPAT": 1.5767518034750687, "VOTRIENT": 1.7737787382242445, "XALKORI": 1.5600961924148244, "XELJANZ": 1.4618532071199102, "XELODA": 2.724589771920116, "XOLAIR": 0.3493651625815734, "XTANDI": 1.9625485294146805, "YERVOY": 1.9562256609931976, "ZOSTAVAX": 0.4754504997150353, "ZYPREXA": 1.7037669501882116, "null": 1.434629195783232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6554.json
index 6da6e667bec..46738978d50 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6554.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6554.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"AZATHIOPRINE": 25.368582931956578, "SIMPONI": 22.14192054465871, "STELARA": 27.37529494542912, "null": 1.192437527941866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6555.json
index f90685d4840..213d4257234 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6555.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6555.json
@@ -1 +1 @@
-{"KYMRIAH": 14899.032451876572}
\ No newline at end of file
+{"ADALIMUMAB": 0.2313298345124522, "AFINITOR": 1.334889285070914, "ALIMTA": 4.906375220694746, "AVASTIN": 20.97968392431629, "BEVACIZUMAB": 11.932955268093648, "BRAFTOVI": 4.20298303462268, "CABOMETYX": 5.225304838393497, "CELLCEPT": 3.026552756252951, "CICLOSPORIN": 1.4135577073085372, "CIMZIA": 1.5291553253172017, "COMIRNATY": 0.031959578437415, "COSENTYX": 0.7987036445668935, "CYTARABINE": 3.5843806823334226, "DEXAMETHASONE": 2.997982674751125, "ENTYVIO": 2.190646988903055, "EXJADE": 0.9831805904855404, "FORSTEO": 1.3478045266379843, "FOTIVDA": 25.87302839628541, "HUMIRA": 3.5102924780317184, "IBRANCE": 0.6103685431048745, "INLYTA": 5.772307478231756, "IPILIMUMAB": 8.507515880975806, "JEVTANA": 7.166339622856966, "KEYTRUDA": 5.594260347331181, "LENVIMA": 11.51869585128959, "LEVETIRACETAM": 3.904256428394869, "MEKINIST": 3.958823432305798, "METHOTREXATE": 1.0558146467764673, "NEXAVAR": 2.091346001228908, "OFEV": 4.069453398153047, "OLANZAPINE": 0.7206244548196398, "OPDIVO": 3.459910889222848, "OPSUMIT": 0.8058822591607095, "PAZOPANIB": 8.819903321288153, "PEGASYS": 0.5207972346986117, "PEMBROLIZUMAB": 2.3067639838674494, "RINVOQ": 5.886135346442828, "RITUXIMAB": 4.14109410597642, "ROACTEMRA": 13.505755687533508, "ROTATEQ": 2.3091471269116965, "SIMPONI": 0.8075383583740108, "SOLIRIS": 3.804749126279064, "SPIKEVAX": 0.0384518995250907, "STELARA": 2.7100246510323367, "STIVARGA": 5.331124309140023, "SUTENT": 4.532238415176344, "TOCILIZUMAB": 23.42307101439506, "TORISEL": 9.980368857218483, "VAXZEVRIA": 0.0323548464521128, "VOTRIENT": 9.403325405167545, "XELJANZ": 2.9454112278608027, "YERVOY": 62.87074018415184, "null": 0.9228930399756164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6556.json
index 498a84bdc51..68e4062e7d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6556.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6556.json
@@ -1 +1 @@
-{"OLANZAPINE": 20.932082239866972, "ZYPADHERA": 3968.163149506781}
\ No newline at end of file
+{"ARAVA": 3.0837490587515157, "ELIQUIS": 3.307317047188706, "FORSTEO": 5.780735429657907, "null": 1.5898654541728443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6557.json
index c3d9becbc4e..40e450cb8a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6557.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6557.json
@@ -1 +1 @@
-{"null": 1.1464456165419163}
\ No newline at end of file
+{"null": 0.8572740378047333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6558.json
index e4a8c1bda08..6e4d410aa6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6558.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6558.json
@@ -1 +1 @@
-{"null": 1.039897555002841}
\ No newline at end of file
+{"OLANZAPINE": 11.009665185739568, "null": 2.7879014645651106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6559.json
index 9966a0402a0..e8b769d672f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6559.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6559.json
@@ -1 +1 @@
-{"AIMOVIG": 128.7630895554759}
\ No newline at end of file
+{"CICLOSPORIN": 4.089746769373476, "CIMZIA": 15.432819973256064, "ENTYVIO": 33.786477235490736, "HUMIRA": 17.9978084263794, "JANUMET": 7.4322839770129585, "LANTUS": 1.905842678583974, "ROTATEQ": 28.288548034055815, "SIMPONI": 3.9241746597883407, "STELARA": 29.873247238992825, "XELJANZ": 3.507109726278421, "null": 0.6282796506939682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/656.json
index 3e209c4fe42..2b9b33a34dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/656.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/656.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 20.6059909811743, "ELIQUIS": 10.049142472550706, "EMPAGLIFLOZIN": 41.14437771362002, "ENOXAPARIN": 38.35073801292001, "ENTRESTO": 5.577796016698047, "LENVIMA": 34.065267325009586, "PLAVIX": 6.355952011316006, "null": 1.3711290779445853}
\ No newline at end of file
+{"VOTRIENT": 41.77293056198687, "null": 1.2289305690104997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6560.json
index 85dfb50a23f..fffd3eb8737 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6560.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6560.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 34.45165026324748, "HUMIRA": 49.12310336964346, "SPIKEVAX": 1.631095481456283}
\ No newline at end of file
+{"ANAKINRA": 1024.923300546897, "ENBREL": 26.293646695383604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6561.json
index b1587391c26..6ed6d3e8c0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6561.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6561.json
@@ -1 +1 @@
-{"ABILIFY": 2.3970855859714644, "AIMOVIG": 2.721819665250952, "ATRIPLA": 1.1646742335734943, "AVAMYS": 2.904813870503962, "BENLYSTA": 3.158375253663774, "BUPRENORPHINE": 10.88150043884504, "CHAMPIX": 1.5219112085969908, "CYMBALTA": 2.88483184122589, "DESCOVY": 40.6177379573548, "FENTANYL": 4.977870474441823, "GARDASIL": 2.764295341272708, "IBUPROFEN": 2.620573818334706, "LATUDA": 15.111620668454814, "LYRICA": 4.852012383894664, "MEPOLIZUMAB": 6.672711702534168, "OLANZAPINE": 2.308234006745232, "STRIBILD": 4.149638767731106, "SUBOXONE": 5.350668358966052, "TRUVADA": 1.7382298802991565, "XELJANZ": 1.1472913009662655, "ZOSTAVAX": 4.142306544511485, "ZYPREXA": 1.6846851543003565, "null": 1.7693589313588756}
\ No newline at end of file
+{"OPSUMIT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6562.json
index 7faa2a9caf8..6a12d67c48c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6562.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6562.json
@@ -1 +1 @@
-{"null": 2.0464318866351654}
\ No newline at end of file
+{"CIMZIA": 19.61052928612009, "ENTYVIO": 59.953559812816586, "FENTANYL": 5.953257521455817, "HUMIRA": 10.039790021350404, "STELARA": 74.89779392570269, "null": 0.4408321274741206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6563.json
index ae01f842e4c..a45aff020d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6563.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6563.json
@@ -1 +1 @@
-{"EYLEA": 67.87894724426535, "ZOSTAVAX": 41.533977139766826}
\ No newline at end of file
+{"MEPOLIZUMAB": 580.8220315751637}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6564.json
index 07bf26e22a9..1889b124c2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6564.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6564.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 5.29562500507369, "ASPARAGINASE": 60.56914711338992, "AVASTIN": 8.302118346397739, "AXITINIB": 15.43629919383513, "BASILIXIMAB": 11.779810246461874, "BEVACIZUMAB": 16.037488480954025, "BORTEZOMIB": 17.30020423427628, "BUSULFAN": 19.12680278572686, "CABOMETYX": 4.379493568592375, "CAPECITABINE": 3.1194627140444022, "CARFILZOMIB": 5.376729770695204, "CELLCEPT": 7.782395812293387, "CICLOSPORIN": 32.447985184985896, "CYTARABINE": 12.250743157607856, "DARZALEX": 3.54957101093443, "DEXAMETHASONE": 4.975472679193486, "ENOXAPARIN": 3.1589555388102832, "FOTIVDA": 27.495954427717464, "HUMAN": 18.32105427120659, "ICLUSIG": 5.8027476188123925, "INLYTA": 16.298877596549946, "KEYTRUDA": 2.826861594893625, "KYPROLIS": 13.729202611871049, "LENVIMA": 12.24705296816257, "METHOTREXATE": 6.247698308403684, "MYCOPHENOLATE": 5.638336859025644, "NEXAVAR": 1.8299282512632653, "NOXAFIL": 6.140828521412818, "ONCASPAR": 15.444983639313, "PAZOPANIB": 12.325488290256157, "PEMBROLIZUMAB": 3.855960667303973, "POSACONAZOLE": 14.205863310938328, "RITUXIMAB": 3.472420200296689, "SOLIRIS": 2.6519255309959227, "STELARA": 3.8796188806632, "STIVARGA": 7.168029557811422, "SUNITINIB": 22.447372708534235, "SUTENT": 2.1505904583878857, "TACROLIMUS": 13.802264725416752, "VFEND": 1.4360096658112311, "VORICONAZOLE": 3.1651550451971406, "VOTRIENT": 10.417503973718985, "XTANDI": 5.153549072430196}
\ No newline at end of file
+{"null": 2.140409623997833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6565.json
index 935a98af1dc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6565.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6565.json
@@ -1 +1 @@
-{"ATRIPLA": 56.94605046303012}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6566.json
index 73393762985..3567e569364 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6566.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6566.json
@@ -1 +1 @@
-{"BRIVARACETAM": 345.63629709145465, "LEVETIRACETAM": 31.91848511431913}
\ No newline at end of file
+{"null": 1.1414720922686423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6567.json
index 5be172f8326..5a2476b95f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6567.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6567.json
@@ -1 +1 @@
-{"LEVETIRACETAM": 272.89342297561643}
\ No newline at end of file
+{"ARAVA": 1.0536919966156768, "CIMZIA": 3.955712277361165, "ENTYVIO": 16.29536186081414, "HUMIRA": 23.34511088061039, "STELARA": 3.444641981642002, "SUTENT": 1.9887555196774245, "null": 1.5123051605907196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6568.json
index 20c2ebdadf7..ff8611058cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6568.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6568.json
@@ -1 +1 @@
-{"GARDASIL": 6.998001069471346, "KEPPRA": 20.826996837189984, "MMRVAXPRO": 4.896427972657276, "null": 2.320858418961638}
\ No newline at end of file
+{"CELLCEPT": 21.81851452191148, "null": 7.668718822441552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6569.json
index 34c01889d12..3d23cce4b78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6569.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6569.json
@@ -1 +1 @@
-{"COMIRNATY": 5.847274064745463, "COVID19": 1.328173316017509, "EVISTA": 2.676355260641452, "SPIKEVAX": 2.570973484005285, "TOZINAMERAN": 3.3506715388992125}
\ No newline at end of file
+{"CABOMETYX": 12.83984879091715, "CIMZIA": 2.8244472843351622, "COMIRNATY": 0.0744134212686448, "ENBREL": 4.907420254631859, "JANUMET": 8.98244915146608, "KEYTRUDA": 3.888771982499427, "LONSURF": 22.33568371094168, "OPSUMIT": 9.08022539009012, "SUTENT": 1.9442020652364504, "null": 0.6986867424823829}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/657.json
index 27f0ffccb8a..dd074b8d170 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/657.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/657.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 9.55799862144343, "null": 1.5613722900121134}
\ No newline at end of file
+{"VOTRIENT": 172.01202449436644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6570.json
index d26f7541e84..57172fa0f3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6570.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6570.json
@@ -1 +1 @@
-{"COVID19": 3.768192100120235}
\ No newline at end of file
+{"ABACAVIR": 4.193291201577518, "BUDESONIDE": 1.6571393910650705, "CLOPIDOGREL": 4.634616317133382, "ELIQUIS": 3.620669766693791, "ENOXAPARIN": 46.4503141240779, "INHIXA": 194.17758788228116, "PLAVIX": 9.324776955013547, "VAXZEVRIA": 0.1157171793846158, "XARELTO": 7.838536786592517, "null": 3.8753675663392544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6571.json
index c9248e0328c..5ac65bceb7e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6571.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6571.json
@@ -1 +1 @@
-{"FENTANYL": 1503.0517445598343}
\ No newline at end of file
+{"CICLOSPORIN": 1.420795851598393, "CLOPIDOGREL": 6.315962699384387, "COMIRNATY": 0.0461397324488704, "CYTARABINE": 3.026902710183785, "ELIQUIS": 9.443070132004106, "ENOXAPARIN": 32.61871515941548, "NEXAVAR": 3.892114291958697, "NOVOSEVEN": 26.907526308012773, "PLAVIX": 8.210247033277858, "SUTENT": 1.7603661827764736, "VOTRIENT": 3.355343304442659, "null": 2.2477926622995192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6572.json
index 4c239e0f31d..5ce035ef7ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6572.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6572.json
@@ -1 +1 @@
-{"null": 15.211422364983385}
\ No newline at end of file
+{"LEVETIRACETAM": 228.95562461413263, "null": 0.8013400042961678}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6573.json
index 6e6e659a4ae..adea616a844 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6573.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6573.json
@@ -1 +1 @@
-{"FENTANYL": 51.36534182441573, "null": 5.961318397796992}
\ No newline at end of file
+{"null": 1.6086976435080844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6574.json
index 25f68494b01..2c261eeb256 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6574.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6574.json
@@ -1 +1 @@
-{"null": 4.1423793880704975}
\ No newline at end of file
+{"null": 1.9007439671806237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6575.json
index e06765f4b86..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6575.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6575.json
@@ -1 +1 @@
-{"null": 1.4704209760613205}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6576.json
index 090855e8899..2d9456112e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6576.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6576.json
@@ -1 +1 @@
-{"DEXDOR": 14791.92902198019, "FENTANYL": 17.049781696539725, "MIDAZOLAM": 40.88554487595712, "SUFENTANIL": 809.6657414852194}
\ No newline at end of file
+{"BEOVU": 392.3353624342832, "EYLEA": 1404.0500274868111}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6577.json
index 62ae84465da..80ed008022b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6577.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6577.json
@@ -1 +1 @@
-{"OLANZAPINE": 28.413322761654747, "null": 1.425377534033471}
\ No newline at end of file
+{"AIMOVIG": 1.9982706949573168, "COMIRNATY": 0.4463645001543242, "CYMBALTA": 0.9064122087254824, "ELIQUIS": 4.284916203597952, "EVENITY": 11.291548026712093, "HUMALOG": 2.024296467413852, "IBRANCE": 1.3117164731224134, "LANTUS": 1.3905716848413328, "PEGASYS": 1.7033087439091097, "PEGINTRON": 4.749091614008878, "PLAVIX": 4.168763969539065, "SIMPONI": 1.697026057988556, "SPIKEVAX": 0.3072926044028109, "STELARA": 2.279222451239645, "TOZINAMERAN": 0.4373696787812904, "VAXZEVRIA": 0.1602927434630091, "XELJANZ": 2.280683351010586, "null": 1.1536759765939195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6578.json
index b0537d2dbc0..dbaefd41ae2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6578.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6578.json
@@ -1 +1 @@
-{"null": 1.561918659840594}
\ No newline at end of file
+{"BRILIQUE": 26.67284348880717, "CLOPIDOGREL": 19.56694440516088, "ELIQUIS": 14.801775912707727, "PLAVIX": 19.372503057913644, "null": 1.599601250419327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6579.json
index 1a0ffea4fdd..3deee07ba04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6579.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6579.json
@@ -1 +1 @@
-{"ELIQUIS": 14.262714572506985, "null": 1.1892535402764817}
\ No newline at end of file
+{"COMIRNATY": 0.4328839511218751, "null": 0.6773544623757338}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/658.json
index a3f99139201..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/658.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/658.json
@@ -1 +1 @@
-{"null": 2.1614517302000533}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6580.json
index 7be555ff883..e538b89e009 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6580.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6580.json
@@ -1 +1 @@
-{"null": 1.1105033216721278}
\ No newline at end of file
+{"CICLOSPORIN": 5.055370875362882, "COMIRNATY": 0.1366646861510684, "null": 0.5049856690640153}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6581.json
index db5f53a7aa1..4e08843e225 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6581.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6581.json
@@ -1 +1 @@
-{"BRIVIACT": 15.260027866893164, "BUPIVACAINE": 9.394036209693931, "BYETTA": 3.716992369920854, "CELLCEPT": 3.968948297810744, "CHLORHEXIDINE": 11.793522732298658, "CICLOSPORIN": 1.3703940940919843, "CIMZIA": 1.899206451373168, "CYMBALTA": 2.927893806217169, "HUMALOG": 3.2183765536974045, "HUMIRA": 2.762556371754778, "IBRANCE": 1.8808450610071417, "LANTUS": 2.0365822140546115, "METHOTREXATE": 2.7115333809502022, "NEXAVAR": 1.966863427245472, "OPSUMIT": 2.066998286045499, "ROACTEMRA": 3.532339241485574, "SIMPONI": 3.95207084057368, "SOLIRIS": 2.703345824660892, "STELARA": 4.089929510783841, "SUTENT": 1.967341214388248, "XELJANZ": 5.953531238236739, "XOLAIR": 2.118523083237267}
\ No newline at end of file
+{"ARIPIPRAZOLE": 8.296640621460803, "ASPARAGINASE": 6.028169170140573, "BEDAQUILINE": 4.175270840027901, "CELLCEPT": 1.4347908439006642, "CICLOSPORIN": 4.667372167414553, "COMIRNATY": 0.2863631063783085, "COTELLIC": 9.021462063065089, "EFAVIRENZ": 13.749198828075608, "GARDASIL": 1.0031017829431508, "KAFTRIO": 17.409540700811423, "KEPPRA": 2.6904306131268694, "KYMRIAH": 3.5156190512935344, "LAMIVUDINE": 8.50540643702899, "MIDAZOLAM": 4.730799739217773, "NAGLAZYME": 21.1625453452651, "NUTROPIN": 66.21940442186816, "OLANZAPINE": 0.9972399412717592, "OMNITROPE": 36.37607540367611, "PEGASYS": 0.565134202249654, "PLAVIX": 0.6816931573829076, "SAXENDA": 2.4364285471812592, "SOLIRIS": 1.847262162630536, "SOMATROPIN": 58.61924593764471, "SPIKEVAX": 0.1262426844746415, "SPINRAZA": 24.771798699238182, "STELARA": 0.7949568205358589, "TEMODAL": 8.988180294232402, "TOZINAMERAN": 0.4165249762836909, "VAXZEVRIA": 0.4454253348644621, "XOLAIR": 1.645663326622907, "null": 1.7267911086956684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6582.json
index d693d25d749..2937a4e0659 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6582.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6582.json
@@ -1 +1 @@
-{"BUPIVACAINE": 41.72040540553686, "FENTANYL": 5.619038551548635, "MISOPROSTOL": 274.6963063577937, "NOVOSEVEN": 49.250872995599, "SUBOXONE": 8.780587660818588, "null": 2.950196851229682}
\ No newline at end of file
+{"TEMODAL": 190.7489374680354, "null": 0.3479807136403974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6583.json
index f0d9682d119..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6583.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6583.json
@@ -1 +1 @@
-{"null": 6.78597621727484}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6584.json
index dbb10d702a6..bda36fd6052 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6584.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6584.json
@@ -1 +1 @@
-{"APIDRA": 21.529138873615903, "HUMALOG": 16.0670790429748, "INSULIN": 55.230240255555074, "NOVORAPID": 97.1444273327776}
\ No newline at end of file
+{"BYETTA": 64.79127645870685, "null": 0.2288849749510079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6585.json
index 779194bf095..b9f4d12f9f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6585.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6585.json
@@ -1 +1 @@
-{"KEYTRUDA": 11.618461616540635, "null": 1.1603316604622087}
\ No newline at end of file
+{"EVISTA": 96.06313467398658, "SIMPONI": 4.656789440064177, "STELARA": 5.76122208355333, "XOLAIR": 5.399930913896246, "null": 1.9346270700297663}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6586.json
index 55d95ba06ce..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6586.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6586.json
@@ -1 +1 @@
-{"ZYPREXA": 58.74823363078491}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6587.json
index 225e4d45ef9..ded352c9703 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6587.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6587.json
@@ -1 +1 @@
-{"AIMOVIG": 1.6442106725342889, "COMIRNATY": 2.6349018986793893, "CYMBALTA": 1.4013405614682828, "EMGALITY": 622.6024985866085, "GARDASIL": 89.93581689493419, "SPIKEVAX": 1.108504098858086, "TOZINAMERAN": 3.8601782300333074}
\ No newline at end of file
+{"null": 0.8400700673806651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6588.json
index 9cecd026769..e4079eb49c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6588.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6588.json
@@ -1 +1 @@
-{"null": 1.244470496613888}
\ No newline at end of file
+{"null": 0.6328555915525093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6589.json
index 57d41259147..48198e5d56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6589.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6589.json
@@ -1 +1 @@
-{"null": 2.0209537743770083}
\ No newline at end of file
+{"null": 0.9986656045005448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/659.json
index 4f1711eb072..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/659.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/659.json
@@ -1 +1 @@
-{"ALISKIREN": 138.6771059963094, "APIDRA": 7.868104115259915, "AVANDAMET": 18.58232363788637, "AVANDIA": 12.997503544288795, "BYETTA": 2.295696457985284, "CLOPIDOGREL": 1.876109739767472, "DALIRESP": 42.69625338462652, "DASATINIB": 19.304223782686, "ELIQUIS": 2.104698133368001, "ENTRESTO": 1.3660595719170066, "EXFORGE": 5.835231522706204, "FORSTEO": 1.1170321285207196, "FORXIGA": 4.753662482475782, "HUMALOG": 6.249310017616688, "HUMIRA": 1.455911695915258, "ICLUSIG": 6.678339062934668, "INSULIN": 2.362149686090582, "JANUMET": 3.056142171303218, "JARDIANCE": 1.8505372665786983, "LANTUS": 3.070562735956315, "LEVEMIR": 4.452209429941644, "NILOTINIB": 10.465354402752332, "PLAVIX": 4.987798560949623, "SOMAVERT": 61.40886252165932, "TASIGNA": 13.056470869488132, "VIAGRA": 6.504272692991568, "null": 1.37592318691517}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6590.json
index b68297f5ca5..1566d5fde92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6590.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6590.json
@@ -1 +1 @@
-{"ABILIFY": 10.40767395781147, "ARIPIPRAZOLE": 4.453217077207204, "ASPARAGINASE": 17.641828859563073, "BEXSERO": 23.76643216495098, "COMTAN": 27.45842688537308, "EVISTA": 9.133056824008086, "GARDASIL": 8.586208258678164, "KEPPRA": 1.4693564018293432, "LEVETIRACETAM": 2.933612361429914, "OLANZAPINE": 13.451442547437908, "ZYPREXA": 3.7193035578131823, "null": 1.7104558170184438}
\ No newline at end of file
+{"null": 1.8527907780345887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6591.json
index c6bef3776f9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6591.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6591.json
@@ -1 +1 @@
-{"null": 2.208597383915884}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6592.json
index 8fede44ebee..74b4ae6e478 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6592.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6592.json
@@ -1 +1 @@
-{"ABILIFY": 2.367437073774622, "BUPRENORPHINE": 2.1222690807636777, "CLOPIDOGREL": 4.426172754512345, "CYMBALTA": 3.570557902202204, "DEXMEDETOMIDINE": 34.47845662404311, "ELIQUIS": 1.0169214738972665, "EMTRIVA": 73.46934545318256, "FENTANYL": 6.544467520121809, "GLIBENCLAMIDE": 15.534782092063216, "IBUPROFEN": 2.1043027363369298, "LEVETIRACETAM": 4.641629947325373, "LYRICA": 5.170883876378313, "MIDAZOLAM": 4.55981190567656, "NOXAFIL": 12.11631913255806, "PLAVIX": 2.329421002551059, "PREGABALIN": 8.965748019361003, "ZYPREXA": 3.118373461953376, "null": 2.746046374425543}
\ No newline at end of file
+{"EYLEA": 302.0983636445462, "null": 0.835030843281158}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6593.json
index 9423582b730..d099207b7a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6593.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6593.json
@@ -1 +1 @@
-{"null": 5.148543192577682}
\ No newline at end of file
+{"null": 0.5703274743427723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6594.json
index b9a5e01bcdf..9df7641c50b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6594.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6594.json
@@ -1 +1 @@
-{"BUDESONIDE": 22.065366433820596, "ENTYVIO": 112.82113200213136, "HUMIRA": 40.0502155324284, "STELARA": 28.60589190480127}
\ No newline at end of file
+{"APIDRA": 1.5364020122179431, "ARAVA": 0.1163651747246393, "AVAMYS": 6.4028405774450325, "AZATHIOPRINE": 7.891742116740974, "AZOPT": 58.93334586442949, "BEOVU": 56.8493830803552, "BIMATOPROST": 333.7598422419329, "BRIMONIDINE": 183.10262380635325, "BRINTELLIX": 1.7979036852893822, "BRINZOLAMIDE": 184.02015038649944, "BROLUCIZUMAB": 62.04947902726558, "BUDESONIDE": 1.1911986196696491, "CHAMPIX": 0.5669283278015809, "CICLOSPORIN": 0.3932474570796466, "CLOPIDOGREL": 0.4156027471197812, "COMIRNATY": 0.1398605754486403, "CYMBALTA": 1.4187338909956562, "DEXAMETHASONE": 0.842325137945682, "ELIQUIS": 0.2269333539203948, "ENBREL": 1.3886691964755566, "EYLEA": 193.9532822944248, "HUMALOG": 0.9365939767830844, "LANTUS": 0.5085470826937755, "LATANOPROST": 308.75645539874336, "LUMIGAN": 159.09026808163892, "LUXTURNA": 429.7422670112431, "MANNITOL": 23.955267672282307, "MEKINIST": 1.2237236694941878, "METHOTREXATE": 0.6958206454843378, "MYCOPHENOLATE": 6.39314413551151, "NAGLAZYME": 3.856241412791796, "NEVANAC": 78.22279537298262, "RELVAR": 3.99282462525096, "SPIKEVAX": 0.0837082048575953, "TOVIAZ": 4.718217787779083, "TOZINAMERAN": 0.1669659136750969, "TRELEGY": 3.9636939573251295, "VAXZEVRIA": 0.0768144451170856, "VIAGRA": 3.578398270193223, "XELJANZ": 0.520174719047422, "ZOSTAVAX": 0.9385954020548536, "ZYPREXA": 0.513954735607525, "null": 1.9523604965321608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6595.json
index 4641590c7e0..f6f4c54bf67 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6595.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6595.json
@@ -1 +1 @@
-{"null": 8.009118968725161}
\ No newline at end of file
+{"ANIDULAFUNGIN": 1512.9765152147052, "COMIRNATY": 0.4954012721255029, "VAXZEVRIA": 1.175446212916454, "null": 0.7965586274764056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6596.json
index 24c8b7d3bcf..9a6562de7fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6596.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6596.json
@@ -1 +1 @@
-{"null": 2.1142542249800265}
\ No newline at end of file
+{"ANIDULAFUNGIN": 697.7867588970669, "COMIRNATY": 0.5115766347067007, "null": 0.990357914416916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6597.json
index 6155c3a27b1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6597.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6597.json
@@ -1 +1 @@
-{"null": 1.9014649402371044}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6598.json
index a0b6f186727..90d62e53fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6598.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6598.json
@@ -1 +1 @@
-{"ABACAVIR": 1.558899743433641, "BUPIVACAINE": 7.210381944502787, "BUPRENORPHINE": 6.531750250919719, "CICLOSPORIN": 5.486072397036593, "CIMZIA": 1.5709950711704197, "COMBIVIR": 7.103361370899588, "DEXAMETHASONE": 2.730073160099671, "DULOXETINE": 18.22811845102764, "ENOXAPARIN": 5.851918563562781, "ENTYVIO": 2.262724999034128, "FENTANYL": 3.1789544420932403, "GARDASIL": 3.0442574078627533, "HUMALOG": 4.591116386320009, "INSULIN": 11.98814642818381, "KEPPRA": 4.933202242129088, "LANTUS": 2.118468687474817, "LEVEMIR": 19.20793612579897, "NEXAVAR": 1.05066620284357, "OLANZAPINE": 1.8631938434424395, "SOLIRIS": 7.7935883153693934, "SUBOXONE": 10.713493428717651, "XOLAIR": 1.1316799740797758, "ZYPREXA": 1.3266885532896364, "null": 1.5344236160866014}
\ No newline at end of file
+{"NOVOSEVEN": 1585.301723097751}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6599.json
index 1c114a75675..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6599.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6599.json
@@ -1 +1 @@
-{"CHAMPIX": 10.136151290194698, "CICLOSPORIN": 3.332431046406912, "GALAFOLD": 171.6906000939662, "IBRANCE": 2.1848773686945995, "LOPINAVIR": 293.05930324646465, "LYRICA": 7.160520774727868, "REVATIO": 18.878108223792363, "STIVARGA": 8.243145150574604, "SUBOXONE": 3.794749168221852, "SUTENT": 1.2727660713782654, "VIAGRA": 16.21813189710212, "XELJANZ": 11.386047523066978, "XOFIGO": 25.73337451081017, "XYREM": 18.91428706978631}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/66.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/66.json
index 71a38723bfa..64f4f609460 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/66.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/66.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 40.26032343992639, "STELARA": 6.920993015896301}
\ No newline at end of file
+{"null": 0.8080245494647719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/660.json
index 44525e73bf5..7a182da6a7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/660.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/660.json
@@ -1 +1 @@
-{"PLAVIX": 47.25363266924098, "null": 2.0528597347076776}
\ No newline at end of file
+{"PEGINTERFERON": 70.14436932856873, "null": 0.2694109304858855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6600.json
index 151544c76c4..464ae39d24d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6600.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6600.json
@@ -1 +1 @@
-{"COMIRNATY": 2.9396643527144874, "SPIKEVAX": 1.030501777484915}
\ No newline at end of file
+{"AVONEX": 2637.989635161719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6601.json
index c445a95d6fb..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6601.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6601.json
@@ -1 +1 @@
-{"null": 1.052774402811636}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6602.json
index 0547657763f..92965adb013 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6602.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6602.json
@@ -1 +1 @@
-{"STELARA": 8.80123540294716, "XELJANZ": 7.302423076228181, "null": 1.2009861248240616}
\ No newline at end of file
+{"COMIRNATY": 7.712974182756422}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6603.json
index 8c4fe48799a..c362372d9bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6603.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6603.json
@@ -1 +1 @@
-{"null": 11.863951839656613}
\ No newline at end of file
+{"null": 0.7764183008908029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6604.json
index 53ba191b2d7..2b0dd6d2c27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6604.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6604.json
@@ -1 +1 @@
-{"KEPPRA": 7.20328845953537, "TESTOSTERONE": 180.70576479241248, "null": 2.692894283708174}
\ No newline at end of file
+{"CICLOSPORIN": 6.543110516313186, "PRIVIGEN": 39.97493580988354, "SOLIRIS": 97.64772412391892, "null": 1.3718160699585138}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6605.json
index 0418b8597f7..a32b94df2c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6605.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6605.json
@@ -1 +1 @@
-{"ABACAVIR": 1.3272271287474966, "ABILIFY": 4.791669390296495, "ADALIMUMAB": 2.08631776103997, "AMINOSALICYLIC": 4.032461398331105, "APROVEL": 3.847905238445936, "ARIPIPRAZOLE": 3.740028233587971, "AZATHIOPRINE": 6.860174707098705, "BARACLUDE": 17.417996214854522, "BRINTELLIX": 8.009044031771037, "CIMZIA": 2.262536937481636, "COMBIVIR": 36.05845446688756, "COSENTYX": 1.3647743911391947, "DEXAMETHASONE": 2.0175715456179266, "EFAVIRENZ": 12.897965922276812, "ELLAONE": 29.27504305039617, "ENTECAVIR": 18.56908384486345, "ENTYVIO": 49.55700468164199, "EPIVIR": 25.296389568421983, "EVRA": 12.377603435493102, "FENTANYL": 2.0975540920171123, "HERCEPTIN": 4.709416242581648, "KEPPRA": 20.902290115072876, "LAMIVUDINE": 8.208890626529648, "LATUDA": 11.366393886709735, "LEMTRADA": 3.202600017487929, "LEVEMIR": 3.3106054400373, "LEVETIRACETAM": 8.080025611062089, "NEVIRAPINE": 24.456437645591368, "NORVIR": 19.068601939595894, "NOVORAPID": 2.5004122990402022, "PANTOPRAZOLE": 2.241306864260675, "REYATAZ": 31.21522719821035, "ROACTEMRA": 1.886952530112929, "SOLIRIS": 6.053885613760671, "STOCRIN": 36.640987519026496, "TAMIFLU": 4.257014348911788, "TRACLEER": 12.145529984146064, "TRUVADA": 1.69699330029499, "VIMPAT": 2.668376815105756, "VIRAMUNE": 17.038471055472254, "VIREAD": 4.715708925021231, "ZERIT": 75.94110485622062}
\ No newline at end of file
+{"BRILIQUE": 11.884602708807543, "CLOPIDOGREL": 14.50152125071638, "COMIRNATY": 0.1512002437832072, "ELIQUIS": 18.218597218379404, "LIXIANA": 13.1756080849217, "PLAVIX": 12.69434483881667, "SPIKEVAX": 0.1745902043687976, "VAXZEVRIA": 0.1793518695865455, "null": 1.38159185076749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6606.json
index e5485cd0945..88062e6663a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6606.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6606.json
@@ -1 +1 @@
-{"ELLAONE": 7627.940313052155}
\ No newline at end of file
+{"null": 4.634437155226893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6607.json
index 89e44eb4cea..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6607.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6607.json
@@ -1 +1 @@
-{"PEGASYS": 12.513707960459236, "STELARA": 26.72668276872753, "TREMFYA": 96.61903333126422}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6608.json
index b18674c594f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6608.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6608.json
@@ -1 +1 @@
-{"CIMZIA": 4.9574817533598505, "KALETRA": 22.731393287479904, "KEPPRA": 8.593821665770419, "NORVIR": 58.381615201498406, "null": 1.6206014677062914}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6609.json
index 701608d2d2d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6609.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6609.json
@@ -1 +1 @@
-{"KEPPRA": 2.1485143653145045, "null": 22.529648166669475}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/661.json
index a85f8afecff..22667dfae3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/661.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/661.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 10.211024499536814, "null": 1.1876078154108285}
\ No newline at end of file
+{"null": 12.426866059035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6610.json
index 4e0ea066fbd..2ebe1cd3a0a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6610.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6610.json
@@ -1 +1 @@
-{"COVID19": 29.767113554509702}
\ No newline at end of file
+{"ABILIFY": 14.918731891158965, "DULOXETINE": 47.54597871822317, "TOZINAMERAN": 1.3387113024887716, "null": 2.349357978913775}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6611.json
index 69da811b16c..4e4d72fb757 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6611.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6611.json
@@ -1 +1 @@
-{"COMIRNATY": 4.585949489481648}
\ No newline at end of file
+{"INFANRIX": 55.15840141036647, "PREVENAR": 219.5863100007606, "ROTARIX": 110.65632499809968, "ROTASHIELD": 607.3828774637363, "ROTATEQ": 2624.760502157841, "TOZINAMERAN": 0.389854695484193, "VAXZEVRIA": 0.0694398521979878, "null": 0.2443397576853717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6612.json
index a0e5c4a19c8..ea638f56046 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6612.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6612.json
@@ -1 +1 @@
-{"null": 1.2099269960988963}
\ No newline at end of file
+{"null": 0.8909720435390208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6613.json
index 34a3d7da7e9..16c3098c62f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6613.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6613.json
@@ -1 +1 @@
-{"EVRA": 158247.44099835248}
\ No newline at end of file
+{"AFINITOR": 3.5070329076266646, "ARAVA": 0.2088509115281599, "AVASTIN": 2.489938334353353, "BEVACIZUMAB": 5.507729703952918, "CAPECITABINE": 12.229958276106494, "COMIRNATY": 0.0537351320100314, "DOCETAXEL": 6.916077914407778, "EVISTA": 37.976951229351, "FAMPYRA": 7.686912450399617, "FASLODEX": 3.5074992033801062, "FULVESTRANT": 14.673567909379614, "KEPPRA": 1.1861003567173014, "OLANZAPINE": 1.2086951206880006, "PACLITAXEL": 9.354798349180683, "ROACTEMRA": 3.565812878482105, "SIMPONI": 2.8940900831427907, "STELARA": 2.8211374456664675, "TESTOSTERONE": 17.39926159304209, "XELJANZ": 0.9512938779220927, "XOLAIR": 2.794409469416894, "null": 4.16252464352996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6614.json
index 47a70acf148..56627a17f00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6614.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6614.json
@@ -1 +1 @@
-{"ATRIPLA": 5.340970659714591, "EFAVIRENZ": 419.6914731861493, "null": 1.184865240038237}
\ No newline at end of file
+{"COMIRNATY": 0.1898579560084924, "null": 3.2115065956266418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6615.json
index f5c4e6b2284..09625d32d70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6615.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6615.json
@@ -1 +1 @@
-{"null": 1.3299487608782574}
\ No newline at end of file
+{"null": 1.5345798162876387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6616.json
index b12f63ec6dc..28b49f6d553 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6616.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6616.json
@@ -1 +1 @@
-{"ABILIFY": 6.548518918479444, "ACTRAPID": 4.277366932055089, "AERIUS": 2.379524819785799, "ALISKIREN": 1.3360520557909277, "ANTIBIOTICS": 4.105853583309913, "APIDRA": 2.436063399738545, "ARANESP": 1.3122846463684068, "ARIPIPRAZOLE": 4.331184355440571, "ASPARAGINASE": 1.6292644448768543, "ATAZANAVIR": 2.871120816341852, "ATOSIBAN": 146.91602308270248, "AZATHIOPRINE": 10.316462656130298, "BETAFERON": 1.0353232941266983, "BIKTARVY": 1.8695344149333573, "BRIVARACETAM": 11.030295800604376, "BUDESONIDE": 1.3960585702898805, "BUPIVACAINE": 14.973621523578668, "BUPRENORPHINE": 9.725551105522197, "BUVIDAL": 5.547184045710002, "CHLORHEXIDINE": 11.610702158928223, "CICLOSPORIN": 4.90229613346597, "CIMZIA": 2.2504761444678416, "CINACALCET": 26.46755019392775, "COMBIVIR": 17.031251404823326, "CRIXIVAN": 5.249943410395293, "CYTARABINE": 1.9281617224211167, "DARBEPOETIN": 8.687828480005768, "DARUNAVIR": 4.793131037156078, "DEXAMETHASONE": 8.904621416655322, "DEXMEDETOMIDINE": 17.384291923192563, "DOLUTEGRAVIR": 5.612270060079436, "DOXORUBICIN": 2.535419214095747, "ECULIZUMAB": 25.52749024781719, "EFAVIRENZ": 2.4924953161738097, "EMTRICITABINE": 6.460503986240286, "ENOXAPARIN": 10.370539212061937, "EPIVIR": 7.312124600425434, "EPOETIN": 8.7230998826782, "ESOMEPRAZOLE": 2.491312112019289, "FENTANYL": 11.979472137574987, "FILGRASTIM": 1.5119235267873707, "FORTOVASE": 15.677764662153026, "GARDASIL": 1.1158828762070092, "HUMALOG": 2.491856840522042, "HUMAN": 5.091361208179787, "HYDROCORTISONE": 5.016327798363761, "IBUPROFEN": 1.9513741097997284, "ILOPROST": 67.05813794476613, "INFLIXIMAB": 2.1480779669871533, "INSULATARD": 9.6183242895605, "INSULIN": 6.539373428793136, "INVIRASE": 5.12318380530117, "IRON": 17.826570928774572, "ISENTRESS": 12.093646925864116, "KALETRA": 3.619797209126382, "KEPPRA": 4.636888109348921, "KIOVIG": 3.379669654386116, "KUVAN": 8.506722303138876, "LACOSAMIDE": 3.538757496942015, "LAMIVUDINE": 5.498225871974321, "LEVEMIR": 12.03020437085858, "LEVETIRACETAM": 2.3094888250466084, "MANNITOL": 8.642685573808313, "MIDAZOLAM": 2.1105320507358947, "MIMPARA": 1.594072088743473, "MYCOPHENOLATE": 2.3976253249398645, "NORVIR": 7.138323483931827, "NOVORAPID": 4.686371898358253, "OPIATES": 39.337907723587456, "OSELTAMIVIR": 10.947227006336307, "PACLITAXEL": 2.2583734658357515, "PANTOPRAZOLE": 1.1018963780675697, "REMICADE": 7.443935901091317, "RITUXIMAB": 1.4759536703980844, "SILDENAFIL": 12.684793034210598, "SOLIRIS": 2.6549410145049994, "STELARA": 1.1553053574732075, "SUBOXONE": 12.613000020992567, "SUFENTANIL": 2.173504966771082, "TACROLIMUS": 6.992214468985721, "TRACTOCILE": 118.04908072199056, "TRESIBA": 2.0994361272620186, "VIMPAT": 1.0290017878813538, "VIRAMUNE": 2.8678991685492417, "XOLAIR": 1.2106271605599257, "ZYPREXA": 1.4137949697343926, "null": 1.781784566366332}
\ No newline at end of file
+{"FORSTEO": 62.73565020039175, "null": 0.4335501018639234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6617.json
index 9661a2a00c0..57423533af3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6617.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6617.json
@@ -1 +1 @@
-{"null": 1.2393608788685448}
\ No newline at end of file
+{"ADALIMUMAB": 2.370025373911349, "ARAVA": 5.911423412758685, "COSENTYX": 8.273479071940628, "CYMBALTA": 6.315326898444037, "HUMIRA": 12.826733171366818, "IBRANCE": 5.782477739868759, "OFEV": 18.684351061546703, "null": 0.5647614148013381}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6618.json
index 1667cede1a4..39ce79f2bd7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6618.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6618.json
@@ -1 +1 @@
-{"ABILIFY": 6.642401606456948, "ACTRAPID": 7.798892225614347, "AERIUS": 3.0167678870271355, "AMBRISENTAN": 6.1744054254780325, "ARANESP": 1.467537486484554, "ARIPIPRAZOLE": 12.103564334365316, "ATAZANAVIR": 6.813730009955076, "ATOSIBAN": 631.9486856443345, "AZATHIOPRINE": 13.080970261225012, "BIKTARVY": 3.368697788612041, "BRIVARACETAM": 24.3147215911612, "BUPIVACAINE": 17.04393497101173, "BUPRENORPHINE": 14.039920316491598, "CHLORHEXIDINE": 12.18509396476181, "CICLOSPORIN": 2.150737763809231, "CIMZIA": 4.610093554704861, "CINACALCET": 20.12054408455916, "COMBIVIR": 10.8441398054403, "CORTICOSTEROIDS": 22.918067778130204, "CYTARABINE": 12.853060264706691, "DARUNAVIR": 9.274468500126233, "DEXAMETHASONE": 7.769951733531802, "DEXMEDETOMIDINE": 22.995042803899363, "DUPILUMAB": 52.25794809196569, "EFAVIRENZ": 3.4151491307965967, "EMTRICITABINE": 10.735411485505155, "ENOXAPARIN": 6.692908556746825, "EPIVIR": 11.130256088603078, "EPOETIN": 14.321792496065203, "FENTANYL": 8.013375404072494, "HUMAN": 2.3316607742190696, "HYDROCORTISONE": 9.296888917729335, "ILOPROST": 100.909144764413, "INFLIXIMAB": 3.81408163964804, "INSULATARD": 10.524812983759936, "INSULIN": 5.361874229152554, "IRON": 6.708356834204396, "ISENTRESS": 11.003633827803116, "KALETRA": 2.7104037076259693, "KEPPRA": 7.094217648025301, "KIOVIG": 5.436984145381256, "LACOSAMIDE": 10.297646952277118, "LAMIVUDINE": 3.7358090888459534, "LEVEMIR": 9.660720204820374, "LEVETIRACETAM": 3.328003682593172, "LOPINAVIR": 7.891521505746379, "MIDAZOLAM": 2.2668278066916305, "MIMPARA": 5.409134156361651, "NORVIR": 9.566251248974568, "NOVORAPID": 2.7337242401064725, "OSELTAMIVIR": 42.38847643028049, "PANTOPRAZOLE": 1.2337309392570524, "REMICADE": 5.9763552053955245, "RITUXIMAB": 1.565495452296369, "SILDENAFIL": 42.25080244367314, "SOLIRIS": 2.4634929034490574, "SPIRONOLACTONE": 3.490646309951432, "SUBOXONE": 25.877519891624942, "TACROLIMUS": 3.789818494331719, "VIMPAT": 1.6632504728741986, "XOLAIR": 1.1347518611120178}
\ No newline at end of file
+{"ADALIMUMAB": 3.7628030309844966, "COSENTYX": 27.848645090313667, "LEVETIRACETAM": 22.82760212343091, "null": 0.5538116827786236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6619.json
index 28559ba3759..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6619.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6619.json
@@ -1 +1 @@
-{"VIAGRA": 53.27596748161916, "null": 3.8687120197152}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/662.json
index 5362665aa61..1409be15e7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/662.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/662.json
@@ -1 +1 @@
-{"KALETRA": 60.86330433956943, "null": 1.214330578981636}
\ No newline at end of file
+{"COMIRNATY": 0.0544198377170844, "CYMBALTA": 5.192083881069792, "EYLEA": 5.011210795054187, "TAMIFLU": 2.790985482849434, "TOVIAZ": 5.705853653412107, "VAXZEVRIA": 0.0593223874104558, "ZYPREXA": 2.476663455096601, "null": 7.204125528668259}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6620.json
index 54bc4a8e252..975479a2cd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6620.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6620.json
@@ -1 +1 @@
-{"ABACAVIR": 2.6015549874251267, "ABILIFY": 3.4091642539582856, "APTIVUS": 50.64353106010293, "ARIPIPRAZOLE": 1.5203647384240844, "AZATHIOPRINE": 20.26522192784463, "BUPRENORPHINE": 3.0328779567838144, "CICLOSPORIN": 8.113477383031176, "COMBIVIR": 13.47592596315812, "DEXAMETHASONE": 3.7535544870881794, "DOXORUBICIN": 4.6279261118858805, "ENOXAPARIN": 6.236331815874247, "FENTANYL": 3.516427589228427, "GARDASIL": 2.631775490923829, "HUMALOG": 2.218312926312457, "HYDROCORTISONE": 5.779270125947948, "INSULIN": 1.8097831212597053, "ISENTRESS": 22.636597583884907, "KALETRA": 4.942252506738883, "KEPPRA": 3.437711479443347, "LEVEMIR": 3.151873147420036, "NORVIR": 18.05163915933248, "OXYBUTYNIN": 10.622350016349966, "PANTOPRAZOLE": 8.194132050849895, "STELARA": 3.057233923924256, "SUBOXONE": 24.61777763860196, "TAMIFLU": 1.8844969038742168, "TRACTOCILE": 55.9556496487921, "XOLAIR": 1.002480454276724, "null": 1.602073256608486}
\ No newline at end of file
+{"null": 3.4551740517825604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6621.json
index 10c9498e876..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6621.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6621.json
@@ -1 +1 @@
-{"BUSULFAN": 114.60410294816032, "COMIRNATY": 1.0810083484226445, "COVID19": 1.3518726933150471, "GARDASIL": 16.00694302108516, "TOZINAMERAN": 1.4622795648460285}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6622.json
index 3cc0c0137da..a96a50dd56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6622.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6622.json
@@ -1 +1 @@
-{"COMIRNATY": 4.484089432891292}
\ No newline at end of file
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6623.json
index 0d0a1acb8df..f56c95c205b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6623.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6623.json
@@ -1 +1 @@
-{"null": 5.907197081000589}
\ No newline at end of file
+{"ADALIMUMAB": 0.471594601163697, "BEOVU": 719.8298957214732, "BRAFTOVI": 10.024771499229317, "BROLUCIZUMAB": 521.3094560837853, "COMIRNATY": 0.6279912324673333, "COSENTYX": 3.037393978749092, "COTELLIC": 12.17139752720167, "DACLATASVIR": 28.21281420339721, "EYLEA": 79.60853766071563, "IPILIMUMAB": 29.247058088192155, "KEYTRUDA": 1.593312166163139, "MEKINIST": 3.4671910377040467, "POSACONAZOLE": 28.55487422693647, "SIMPONI": 4.688448772000083, "SPIKEVAX": 0.2591594389615325, "TOZINAMERAN": 0.7851609662177684, "VAXZEVRIA": 0.2689255680774584, "ZELBORAF": 18.59357782861868, "ZOSTAVAX": 2.5704444302917526, "null": 0.5163508019991964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6624.json
index 5eec8be6e27..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6624.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6624.json
@@ -1 +1 @@
-{"ATAZANAVIR": 32.343802528227194, "ATOSIBAN": 124.85658155349412, "BUPRENORPHINE": 7.456442850774994, "CIMZIA": 2.7935991501198085, "COMBIVIR": 31.29985680412729, "EFAVIRENZ": 25.179919969416503, "EPIVIR": 17.51643184253225, "EPOETIN": 56.56878537110124, "GARDASIL": 2.2741795034101595, "ISENTRESS": 27.886813253642085, "KALETRA": 14.324702326996333, "LANTUS": 1.514457470652892, "NORVIR": 36.794002436428336, "PEGASYS": 1.294887733006703, "SUBOXONE": 8.098585419617384, "TAMIFLU": 4.02042901331533, "null": 1.3062226567621271}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6625.json
index f4471342c6b..de55d62633b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6625.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6625.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 5.754082094937249, "CYMBALTA": 1.8952854269468584, "SUBOXONE": 13.2070798210606, "null": 2.630739988370026}
\ No newline at end of file
+{"BEOVU": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6626.json
index 81668ddc802..e0ff7a001e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6626.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6626.json
@@ -1 +1 @@
-{"COMIRNATY": 3.786163247309833, "TOZINAMERAN": 6.287452566398694}
\ No newline at end of file
+{"HUMIRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6627.json
index 82f72fc50bc..4aab17dd23b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6627.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6627.json
@@ -1 +1 @@
-{"COMIRNATY": 4.660515762898247}
\ No newline at end of file
+{"null": 2.1571591563082437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6628.json
index bfb05f7dc87..5d862438343 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6628.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6628.json
@@ -1 +1 @@
-{"COMIRNATY": 8.717170755048063, "COVID19": 1.3582349028265717, "SPIKEVAX": 2.583839208313918, "TOZINAMERAN": 3.871367820119668}
\ No newline at end of file
+{"null": 1.1612954020848236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6629.json
index bd5f28d008e..cfbf85a9ca4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6629.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6629.json
@@ -1 +1 @@
-{"COMIRNATY": 11.47569156296703, "SPIKEVAX": 2.114200739273832, "TOZINAMERAN": 2.5097851662107797}
\ No newline at end of file
+{"MELPHALAN": 421.6769635803152, "NEVANAC": 1279.1583091864472, "null": 2.162401222338949}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/663.json
index 4be11edb934..0c904cb8e47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/663.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/663.json
@@ -1 +1 @@
-{"AVANDIA": 6.678563257384186, "HUMALOG": 4.0712360669832846, "TASIGNA": 28.642650355179452}
\ No newline at end of file
+{"COMIRNATY": 0.3255400413922832, "IBUPROFEN": 7.9874225207337854, "PEGASYS": 6.427978045524723, "SUTENT": 4.023956704497161, "VAXZEVRIA": 0.3433968962579011, "null": 0.9128000201144456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6630.json
index 082fbce57ba..37c8f54500c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6630.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6630.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 4.850860782404132, "ENTRESTO": 4.001117735199706, "FORXIGA": 11.208260245431289, "JARDIANCE": 6.8974527321722645, "KEYTRUDA": 5.650137096600775, "null": 1.5885845522789088}
\ No newline at end of file
+{"null": 1.7924900272218691}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6631.json
index 3f8a9340f8d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6631.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6631.json
@@ -1 +1 @@
-{"ABATACEPT": 33.73003723200497, "ARAVA": 9.149546053071983, "ENBREL": 19.693155027798845, "MEPOLIZUMAB": 26.942616045164947}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6632.json
index 7b9a914e041..b84824ad96a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6632.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6632.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"null": 2.488539847645202}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6633.json
index 3d9cded81a1..eea3e5d16a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6633.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6633.json
@@ -1 +1 @@
-{"HUMALOG": 6.14435445555031, "ZOSTAVAX": 72.72294497439263}
\ No newline at end of file
+{"null": 13.155134570170723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6634.json
index 73a9988ee5e..4d7a1f05877 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6634.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6634.json
@@ -1 +1 @@
-{"ABACAVIR": 53.5035246367101, "ABATACEPT": 1.539520961258974, "ABILIFY": 14.971827050956584, "ADALIMUMAB": 2.6491991862380067, "AERIUS": 2.6415720808597025, "APREMILAST": 3.014320009463184, "ARIPIPRAZOLE": 11.66995420164655, "ATAZANAVIR": 4.220689305099393, "BRINTELLIX": 4.434573670795789, "BRIVARACETAM": 4.52465246155034, "BRIVIACT": 5.712132665153324, "BUPIVACAINE": 6.7239760323819455, "BUPRENORPHINE": 2.335282693055624, "C1": 54.40658618686044, "CANCIDAS": 2.001241869493409, "CINRYZE": 24.101428144326384, "CIRCADIN": 11.727236751747808, "CUBICIN": 1.8413075439555, "CYMBALTA": 2.884757437136783, "EFIENT": 3.788697294503779, "ELIQUIS": 4.478169672840556, "FIRDAPSE": 5.580106995554496, "IKERVIS": 42.16403842664547, "IPILIMUMAB": 3.019148756330173, "KEPPRA": 2.183719119058245, "LACOSAMIDE": 1.977153121214298, "LATUDA": 4.176899015217927, "LYRICA": 1.7022688897918796, "MICARDIS": 1.1370270877376465, "NOXAFIL": 4.341061389787439, "OLANZAPINE": 6.759460124181447, "OPDIVO": 4.195065923211207, "PLAVIX": 4.576202617219796, "REVATIO": 6.408397397325239, "SUBOXONE": 4.142747720913503, "SYCREST": 9.10113487826083, "TOVIAZ": 1.8795365706934564, "VFEND": 1.5858966089992406, "VIMPAT": 1.0696341496286728, "XELJANZ": 1.0870465950561172, "YERVOY": 32.797987113559344, "ZYPADHERA": 25.019653221165527, "ZYPREXA": 43.68725474392463, "null": 1.1366071849920338}
\ No newline at end of file
+{"null": 0.6780206922776975}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6635.json
index bc70d21d999..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6635.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6635.json
@@ -1 +1 @@
-{"ABATACEPT": 2.223185444810729, "ABILIFY": 6.380167763945899, "ADALIMUMAB": 5.6176672053528085, "AMINOSALICYLIC": 3.1467426373590417, "ANAKINRA": 16.092328740094636, "APIDRA": 1.0290717790966504, "ARAVA": 3.5587368366656547, "BENLYSTA": 1.0632702447291478, "BRINTELLIX": 2.0943634386167918, "BRUKINSA": 37.800265656865406, "CLOPIDOGREL": 3.195652594005692, "ELIQUIS": 55.06955722708253, "ENTRESTO": 12.828336572077127, "ERLEADA": 8.501462338724695, "FAMPYRA": 17.568032037353976, "FEBUXOSTAT": 8.9209062405223, "GILENYA": 10.849328929140706, "INCRUSE": 4.582914788213763, "IPILIMUMAB": 4.603506628675699, "LATUDA": 26.845203589340443, "LIXIANA": 2.2922989361270742, "LONSURF": 12.061890520799398, "NERLYNX": 70.74528973363854, "OBINUTUZUMAB": 59.929557590833554, "OPDIVO": 4.590715224437839, "PEMBROLIZUMAB": 3.812801396102118, "PLEGRIDY": 2.395254961160316, "RUBRACA": 16.198406409227303, "SPINRAZA": 7.158483424727773, "SPRYCEL": 52.94852112096044, "VALSARTAN": 28.444418686658093, "VIMPAT": 2.582923215234883, "XARELTO": 4.39168114912845, "XTANDI": 15.400983405917302}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6636.json
index b020e24ef83..38389377e79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6636.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6636.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 8.015065640435287, "CHAMPIX": 5.228148959205406, "CLOPIDOGREL": 2.604691817051813, "FENTANYL": 3.997754490630531, "HUMALOG": 1.4402477621970784, "JANUMET": 3.329489056769431, "LYRICA": 2.698008873189033, "PREGABALIN": 31.10758205898569, "SAXENDA": 10.492383405543332, "SILDENAFIL": 14.7685029771604, "TESTOSTERONE": 22.69348618358044, "TRELEGY": 10.09147209738475, "VIAGRA": 30.780490277612422, "XELJANZ": 1.1285457433364858, "null": 2.799558603875971}
\ No newline at end of file
+{"null": 32.607708990302235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6637.json
index 8a53c22d67e..6aaa53e3a58 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6637.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6637.json
@@ -1 +1 @@
-{"null": 9.934545626438448}
\ No newline at end of file
+{"BEOVU": 289.3688999601866, "CIMZIA": 1.7982445559183882, "COMIRNATY": 0.484750645487766, "COSENTYX": 10.13233286193664, "ENBREL": 2.097789978121071, "EYLEA": 110.44677006867646, "KEYTRUDA": 1.656817178875162, "ROACTEMRA": 3.912833224339235, "SIMPONI": 3.84155856542062, "SPIKEVAX": 0.4681831326843541, "TOZINAMERAN": 0.3322879072908576, "VAXZEVRIA": 0.1987255461820949, "ZOSTAVAX": 8.010403915668682, "null": 0.9495807649599388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6638.json
index 7320803708d..e352dbb8907 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6638.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6638.json
@@ -1 +1 @@
-{"OLANZAPINE": 22.70129626412294, "null": 2.9538777157993703}
\ No newline at end of file
+{"SOLIRIS": 64.20905133480194, "null": 0.3462340875624367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6639.json
index ba2240c71f8..953ee2a9fd2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6639.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6639.json
@@ -1 +1 @@
-{"APIDRA": 1.079342489754255, "BEXSERO": 1.3192575896762229, "BRILIQUE": 1.1599869284891493, "BRIMICA": 62.267975873994246, "CERVARIX": 5.612881996941176, "COMIRNATY": 2.4906942225785835, "CORTICOSTEROIDS": 4.854771962447388, "EMPAGLIFLOZIN": 4.06641024417524, "ENTRESTO": 1.1113474521369529, "ENZALUTAMIDE": 2.195981414943367, "FLUCELVAX": 2.7529746701902518, "GARDASIL": 5.7534832119186845, "HUMALOG": 1.1490104800619316, "IVABRADINE": 19.74648643544044, "KARVEA": 11.031226228445153, "KARVEZIDE": 6.236679600672139, "MENVEO": 5.491821028525964, "MICARDIS": 1.479077831167285, "MICARDISPLUS": 8.445860528172176, "MMRVAXPRO": 1.3650749822789712, "NIMENRIX": 5.41333610801312, "NOVONORM": 2.031940858440355, "OPSUMIT": 1.1357787443333804, "PREVENAR": 2.011442219048233, "PRITORPLUS": 15.515070674962002, "QUTENZA": 2.39788887399838, "RANEXA": 1.7121289161320918, "RAPISCAN": 4.7424936056094, "REMICADE": 1.0483068555166208, "RIVAROXABAN": 1.7650201557170933, "SILDENAFIL": 1.621784480167223, "SPIKEVAX": 2.5206626242489656, "TOZINAMERAN": 1.619487899725322, "TWINRIX": 1.1170211616906092, "UROREC": 4.319022426315292, "ZYPADHERA": 1.152536872800983}
\ No newline at end of file
+{"APREMILAST": 16.683504571789697, "ARANESP": 24.002043816609508, "ARAVA": 0.2439288808269658, "ARIPIPRAZOLE": 2.777450623342715, "BUDESONIDE": 1.6328114973011758, "COMIRNATY": 0.7522818310022098, "ELIQUIS": 1.7672242980321051, "EMPAGLIFLOZIN": 10.507505644919796, "ENTRESTO": 1.596379138206012, "ENTYVIO": 7.683403382631144, "ESOMEPRAZOLE": 64.44304810144143, "FORSTEO": 1.6385104692576349, "GARDASIL": 2.7022190776147137, "HUMIRA": 5.015860679203612, "IBRANCE": 1.3148888708392377, "JAKAVI": 2.704246404773918, "NEXAVAR": 2.1646648075155395, "OPSUMIT": 2.4377195306507677, "PREGABALIN": 11.341693465278336, "SPIKEVAX": 0.272137545424176, "STELARA": 0.9934004658294018, "SUTENT": 0.8245376182049555, "TOZINAMERAN": 0.540856310957958, "VAXZEVRIA": 0.2687600163582956, "XELJANZ": 1.0026811687609103, "ZOSTAVAX": 1.5719936367751286, "null": 0.6086599196156309}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/664.json
index 163ba28af50..ca8f422ecaa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/664.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/664.json
@@ -1 +1 @@
-{"null": 1.0969360158005672}
\ No newline at end of file
+{"ABILIFY": 0.2403655400282998, "AGOMELATINE": 8.890327335125598, "ARIPIPRAZOLE": 0.308870118921584, "ATRIPLA": 62.04638342318317, "BEOVU": 0.7141512687648353, "BRINTELLIX": 0.190572492306892, "CHAMPIX": 0.2595512584511347, "COMIRNATY": 0.0025347577783073, "CONTRAST": 3.1655396872128843, "CYMBALTA": 0.1455437775371952, "GARDASIL": 0.0768171338085977, "KALETRA": 1.6528734066743918, "LATUDA": 0.33654920983333, "LEVETIRACETAM": 0.2344077663466073, "OLANZAPINE": 0.2300977452537832, "OPTIMARK": 15.623318961576356, "PLAVIX": 0.3636464605316323, "STRIBILD": 37.93305612535252, "TRUVADA": 36.234057817902766, "VIREAD": 20.621645383123106, "ZYPREXA": 0.1051496678977143, "null": 0.3865692317400482}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6640.json
index 5aa12832fe5..54a2101d821 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6640.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6640.json
@@ -1 +1 @@
-{"HYDROCORTISONE": 105.9744567718501}
\ No newline at end of file
+{"ADCIRCA": 11.760869986450256, "ADEMPAS": 12.12754623459814, "AFINITOR": 2.320550473135397, "AMBRISENTAN": 16.056181177196063, "AMINOSALICYLIC": 3.75298833953584, "ARAVA": 0.6022845300625161, "ARIPIPRAZOLE": 3.5482484313285685, "BRAFTOVI": 3.6474639324354015, "BRILIQUE": 6.686167001461, "BUDESONIDE": 1.9770905686873803, "BUMETANIDE": 9.450332269215345, "BYETTA": 4.924134204705148, "CELLCEPT": 1.2257635420071613, "CIMZIA": 2.181421129313813, "CLOPIDOGREL": 4.450200582460544, "COMIRNATY": 0.2552551559965473, "CYMBALTA": 0.6705184748989488, "ELIQUIS": 5.346409718575211, "ENTRESTO": 1.0913740825801623, "ENTYVIO": 1.93081226472393, "EPADERM": 266.32579582675174, "EVISTA": 4.782881162023502, "FASLODEX": 2.581671835801861, "FORSTEO": 0.9888334263200708, "GARDASIL": 2.107669505827176, "HUMALOG": 0.438732426358162, "HUMIRA": 1.4216724611668017, "IBRANCE": 1.1047272205098315, "INSULIN": 1.915866876868847, "JANUMET": 4.58549416376921, "JANUVIA": 2.7309243044453506, "KEYTRUDA": 0.5595119073213632, "LIXIANA": 11.549025938002483, "METHOTREXATE": 0.880147435204345, "MICARDIS": 2.773267079866394, "MIRCERA": 7.844994036596608, "NPLATE": 2.9426702058616923, "OPSUMIT": 5.238459160154789, "PEGINTRON": 1.0821806092152952, "PLAVIX": 6.181051755205363, "PRADAXA": 16.162394879373352, "SIMPONI": 0.8531605022080996, "SPIKEVAX": 0.1458396553032816, "SPRYCEL": 2.6313255460329703, "STELARA": 2.353740892020551, "SUTENT": 0.5495781668822588, "TASIGNA": 3.2040630964327983, "TICAGRELOR": 4.468393646110373, "TOZINAMERAN": 0.135546860512224, "TRACLEER": 1.9401409138986847, "VAXZEVRIA": 0.0800601452600195, "XARELTO": 8.012358241119333, "XELJANZ": 0.9013026974580292, "ZOSTAVAX": 3.614709314264672, "ZYPREXA": 2.341608437646726, "null": 0.8996608143418157}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6641.json
index fb4aed077ba..57e181f2be7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6641.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6641.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 8.957155721246615, "OLANZAPINE": 26.895689545416836, "RISPERIDONE": 54.40247395563022, "SILDENAFIL": 52.61127406357554, "SUBOXONE": 2.088614001504605, "VIAGRA": 134.18168756080345, "ZYPREXA": 12.411333828450598, "null": 1.5266557021739875}
\ No newline at end of file
+{"ARIPIPRAZOLE": 68.72066479252251, "null": 1.095101614929364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6642.json
index ea3ca6ad539..d8618263045 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6642.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6642.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 25.63798001918226, "KEYTRUDA": 18.042906794702397, "NOXAFIL": 124.51802954776834, "OPDIVO": 35.38583373398441, "POSACONAZOLE": 333.4399540432499}
\ No newline at end of file
+{"ALEMTUZUMAB": 25.21342952758611, "ARANESP": 11.93860256925485, "CICLOSPORIN": 5.151892734423569, "EXJADE": 144.148417187257, "JAKAVI": 21.953949849237564, "PEGASYS": 3.2150869425324564, "SOLIRIS": 32.5748009006544, "null": 0.5373484179216562}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6643.json
index 9dac5245ade..222cbbe26ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6643.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6643.json
@@ -1 +1 @@
-{"OCALIVA": 131.2628631456531, "null": 1.031516512074019}
\ No newline at end of file
+{"COMIRNATY": 0.6314659520094018, "SPIKEVAX": 0.5829387086166014, "TOZINAMERAN": 1.906299909366586, "VAXZEVRIA": 0.6156755977938507, "null": 1.7706665342973893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6644.json
index ae44c0227bf..9c0747fe8c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6644.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6644.json
@@ -1 +1 @@
-{"COVID19": 4.301706552270272}
\ No newline at end of file
+{"null": 0.569459501492322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6645.json
index 06e79496f46..7bf728cc33d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6645.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6645.json
@@ -1 +1 @@
-{"null": 1.9666797076280187}
\ No newline at end of file
+{"COMIRNATY": 0.4312302438541386, "null": 1.0398441250054362}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6646.json
index b79f649bace..6ed6d3e8c0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6646.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6646.json
@@ -1 +1 @@
-{"BUSULFAN": 400.9560442398337}
\ No newline at end of file
+{"OPSUMIT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6647.json
index dd111ce4128..f962de10df7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6647.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6647.json
@@ -1 +1 @@
-{"IPILIMUMAB": 55.39933377858444, "KEYTRUDA": 14.76351931431538, "OPDIVO": 32.870005717940174, "PEMBROLIZUMAB": 87.03208616193082, "SUTENT": 5.188114909023682}
\ No newline at end of file
+{"ABACAVIR": 0.2119259221114613, "ABILIFY": 6.643878975327891, "AERIUS": 1.33868168318507, "AIMOVIG": 1.7795789568187594, "ANTIBIOTICS": 2.3181772749494387, "ARIPIPRAZOLE": 4.684636109105737, "ATRIPLA": 0.1018203620267083, "AUBAGIO": 0.2867414226152726, "AZATHIOPRINE": 0.4359239822462786, "BEDAQUILINE": 1.4763018824364018, "BENLYSTA": 0.3233154592949867, "BENZODIAZEPINE": 1.749761799242925, "BEXSERO": 10.701735980202338, "BIKTARVY": 1.3986101691409725, "BRINTELLIX": 4.6782296275476245, "BRIVARACETAM": 9.978643256492289, "BRIVIACT": 11.549594880680846, "BUDESONIDE": 0.3547798644365955, "BUPIVACAINE": 0.5890107390061293, "BUPRENORPHINE": 1.739265031566802, "BYDUREON": 0.5377285469563424, "BYETTA": 0.1837749939023229, "CAFFEINE": 6.625733662931749, "CELLCEPT": 0.1472418391462066, "CHAMPIX": 10.08026302621828, "CICLOSPORIN": 0.1314065367104489, "CIMZIA": 0.0532714595753855, "CIRCADIN": 3.2311703806684937, "COMBIVIR": 0.8268292551245129, "COMIRNATY": 0.2661193561561843, "COMTAN": 2.9367405916663856, "COSENTYX": 0.2057146821046402, "CYMBALTA": 19.784871304038678, "DAKLINZA": 2.8895881842654707, "DEXAMETHASONE": 0.3551745857976198, "DULOXETINE": 2.443513382002993, "EFAVIRENZ": 1.226685913618166, "ELIQUIS": 0.1329182169085738, "ENTACAPONE": 4.337784025041486, "ENTRESTO": 0.1157870451752898, "EPCLUSA": 1.0892781752356249, "EPIDYOLEX": 9.332367231185929, "FAMPYRA": 0.7513985536229841, "FASLODEX": 0.1763451586985412, "FENTANYL": 0.3804917562381453, "FORXIGA": 0.1926646608875026, "FYCOMPA": 23.39228841290309, "GARDASIL": 0.7132076571567805, "HARVONI": 0.9451410049762664, "HEMANGIOL": 11.936315204990535, "HEXACIMA": 15.449408688737986, "HEXYON": 7.457766920929498, "HUMALOG": 0.3783594795750704, "IBRANCE": 0.3080152363489565, "IBUPROFEN": 0.4521119992726983, "INCIVO": 1.5046693463435383, "INFANRIX": 18.346563844208774, "INSULIN": 0.4745432379940488, "INTRONA": 3.725740395822753, "IRON": 1.3729151519357334, "ISENTRESS": 1.0108874633927871, "JANUMET": 0.2969735236411917, "JANUVIA": 0.2094225148257538, "JARDIANCE": 0.1406352044347941, "KAFTRIO": 4.918817588360969, "KALETRA": 0.4799719614077657, "KEPPRA": 7.341932714171782, "KEYTRUDA": 0.1285337530768643, "KYMRIAH": 0.360909631906715, "LACOSAMIDE": 2.794400076202445, "LANTUS": 0.3599666170620672, "LATUDA": 3.5465622224739874, "LEVETIRACETAM": 7.37782235224648, "LEVODOPA": 3.0532151637333187, "LEVOFLOXACIN": 0.4286527472244009, "LURASIDONE": 5.092521876100791, "LYRICA": 1.0212814413458515, "MELATONIN": 2.755614307086228, "MENVEO": 3.8496148963415657, "METHOTREXATE": 0.1339923190721345, "MIDAZOLAM": 0.9314066530415708, "MMRVAXPRO": 4.687366836203584, "NALOXONE": 9.066761837087205, "NIMENRIX": 1.977702249004308, "NOT": 0.7208208467812374, "NUCALA": 0.773801864125724, "OCRELIZUMAB": 0.5509346767132285, "OLANZAPINE": 2.66494993363812, "OLYSIO": 2.391928031987029, "PEGASYS": 5.051000417285198, "PEGINTERFERON": 2.3773343510132965, "PEGINTRON": 3.650876056663505, "PERAMPANEL": 17.188830656331135, "PLAVIX": 0.1078620087705834, "PREGABALIN": 1.2513086434332168, "PREVENAR": 9.270499536555484, "PRIVIGEN": 0.4490436552641936, "REBETOL": 2.2745944551256123, "RIBAVIRIN": 1.8665281585033116, "RISPERIDONE": 2.9414778197824805, "ROTATEQ": 14.852156507491006, "RYEQO": 6.512210919621305, "SAXENDA": 0.3855139970963279, "SHINGRIX": 0.1166822416518507, "SIMPONI": 0.139508726251944, "SLENYTO": 30.746272970693337, "SOVALDI": 1.1422031031773596, "SPIKEVAX": 0.1688862777298251, "SPINRAZA": 0.488977077448383, "STELARA": 0.1211231945722785, "SUBOXONE": 2.8227561808396064, "SUTENT": 0.2413746752910888, "SYNAGIS": 3.815405786273261, "TAMIFLU": 1.2005607051630396, "TESTOSTERONE": 1.3010883010551468, "TOZINAMERAN": 0.8801056506237798, "TRELEGY": 0.2139099186602009, "TRIUMEQ": 2.5451245186720466, "TRULICITY": 0.385983226458733, "TWINRIX": 0.6301530078607729, "VARENICLINE": 9.44070437648679, "VAXZEVRIA": 0.295055476336048, "VFEND": 0.5171333011470961, "VICTOZA": 0.2657115453479775, "VIMPAT": 4.579239420117863, "VORTIOXETINE": 17.815645187684645, "WAKIX": 8.507436424297984, "XELJANZ": 0.2860989113763337, "XOLAIR": 0.2906367290847071, "XTANDI": 0.1962703971269173, "XYREM": 4.2590883169872695, "ZEPATIER": 2.3671321153450804, "ZOSTAVAX": 0.2306012114090019, "ZYPADHERA": 1.8829792959738083, "ZYPREXA": 1.1318878345693024, "null": 1.5576698872280557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6648.json
index 328a3ecdf2e..654822522c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6648.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6648.json
@@ -1 +1 @@
-{"YESCARTA": 376.71858990274416}
\ No newline at end of file
+{"BEXSERO": 18.805435131999744, "COMIRNATY": 0.0167516512948761, "INFANRIX": 17.769163721857655, "MMRVAXPRO": 593.8582125548261, "PREVENAR": 28.962621222091308, "ROTATEQ": 2.4578526523356543, "null": 1.4771465631198295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6649.json
index fb0f7673cf7..ba44c004527 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6649.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6649.json
@@ -1 +1 @@
-{"JAKAVI": 400.4249844935871, "RUXOLITINIB": 453.3999335105938}
\ No newline at end of file
+{"ABATACEPT": 28.471055383750624, "ABILIFY": 0.4260094275817681, "ACETAMINOPHEN": 51.21877906216128, "ACTOS": 5.016586896530147, "ADALIMUMAB": 10.958303698148963, "AIMOVIG": 2.01810341453164, "AMINOSALICYLIC": 0.6976753672589738, "ANAKINRA": 0.7324597061280901, "APREMILAST": 1.5029437112780772, "APREPITANT": 12.84806847105128, "ARAVA": 7.768512523980321, "AUBAGIO": 0.8346770495641319, "BENLYSTA": 0.5022030727766256, "BRINTELLIX": 0.5958410386848745, "BUDESONIDE": 0.194339804578744, "BYDUREON": 0.446921168435241, "BYETTA": 0.8438393628902701, "CHAMPIX": 0.472971768814559, "CHLORHEXIDINE": 78.50191678620189, "CIMZIA": 29.225412989568053, "COMIRNATY": 0.1100019369438015, "COSENTYX": 1.0783599390341634, "CYMBALTA": 0.4761143385148971, "DEXAMETHASONE": 0.3302730128612822, "ELIQUIS": 0.2798526878703211, "ENBREL": 0.6071000261553418, "ENTYVIO": 0.7771694578727226, "ERELZI": 11.0230233690825, "EXJADE": 0.3646783273177301, "FASLODEX": 0.6269299791107458, "GARDASIL": 2.4528970980124982, "HARVONI": 1.5072052750318543, "HUMALOG": 0.615701882422732, "HUMIRA": 0.9375607066106244, "IBRANCE": 0.2394358236310855, "JANUMET": 0.5373535990681552, "JANUVIA": 1.272284663079558, "KEPPRA": 0.1699105792250929, "LANTUS": 0.1284246973771826, "LEVOFLOXACIN": 0.275982623996601, "LYRICA": 0.7556787434847196, "PANTOPRAZOLE": 0.8261316886392722, "PEGASYS": 0.1954095617287372, "PLAVIX": 0.4350023490857302, "RIBAVIRIN": 0.8500766550939829, "RITUXIMAB": 1.4770227711142654, "SPIKEVAX": 0.1128776384399409, "STELARA": 0.3028793279085418, "SUTENT": 0.1591407232009266, "TOZINAMERAN": 0.5563927466882579, "VAXZEVRIA": 0.185024303502348, "XELJANZ": 0.956723147549598, "XOLAIR": 0.3888776111020556, "ZOSTAVAX": 1.9065380798040716, "ZYPREXA": 0.4797909968126669, "null": 0.8254244135944155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/665.json
index 433488fbeb7..c9a2d6cd842 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/665.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/665.json
@@ -1 +1 @@
-{"null": 2.0344411705489893}
\ No newline at end of file
+{"COMIRNATY": 0.2057245673258245, "null": 2.4331755511674102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6650.json
index aa1156988e2..780e6a03494 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6650.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6650.json
@@ -1 +1 @@
-{"FAMPYRA": 614.9804246750336}
\ No newline at end of file
+{"AVANDAMET": 10.738798988022532, "AVANDIA": 11.298375858973191, "BUPIVACAINE": 6.120662639760171, "CLOPIDOGREL": 2.252372075374548, "COMIRNATY": 0.5371254549005161, "ELIQUIS": 2.0753674197900955, "FENTANYL": 1.1942352391146511, "IBUPROFEN": 2.372733228347009, "LACOSAMIDE": 6.019949753652213, "LANTUS": 0.8713935359213487, "NOVOSEVEN": 16.876166078491035, "PLAVIX": 1.3872182808558935, "RASILEZ": 7.462843935712358, "SPIKEVAX": 0.3901620146340966, "SUTENT": 0.7586344813751846, "TASIGNA": 7.442627647016176, "TOZINAMERAN": 0.3349335622362295, "VAXZEVRIA": 0.3784085960966906, "VOTRIENT": 1.6599043375148834, "ZOSTAVAX": 0.9545946639281048, "null": 1.515972597637638}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6651.json
index 147eee38742..170a235ecef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6651.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6651.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0907433004614857, "COVID19": 12.462343133790666, "SPIKEVAX": 1.6073921744684014, "TOZINAMERAN": 2.2666109172251563}
\ No newline at end of file
+{"AVANDAMET": 169.05160863372032, "AVANDIA": 234.05620985013016, "BRILIQUE": 5.458055755808496, "CLOPIDOGREL": 3.984839274640039, "COMIRNATY": 0.0548679324666554, "DASATINIB": 27.773926467812952, "ELIQUIS": 1.1676802014208898, "ENTRESTO": 19.16912200475098, "GLIBENCLAMIDE": 19.06529631221713, "PLAVIX": 1.827764767286279, "TASIGNA": 4.208693724799727, "VALSARTAN": 15.20171955356789, "null": 0.4221489328179222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6652.json
index ec1ec0c75c7..086ce7651a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6652.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6652.json
@@ -1 +1 @@
-{"BRIDION": 51.033546921024985, "CELSENTRI": 147.42765613363318, "FENTANYL": 14.71802832294206, "ICLUSIG": 34.87955655555459, "RELVAR": 44.71070060516731, "null": 1.543899368135592}
\ No newline at end of file
+{"COMIRNATY": 1.908670214617804, "CYMBALTA": 2.6220188957517583, "ELIQUIS": 4.969720177195407, "EVENITY": 22.582858916587057, "SPIKEVAX": 1.157214934056716, "VAXZEVRIA": 0.9117468455090474, "null": 0.4832536882429608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6653.json
index 58968e85fc4..d63813e82f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6653.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6653.json
@@ -1 +1 @@
-{"SPIKEVAX": 19.325597411746887}
\ No newline at end of file
+{"TEMOZOLOMIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6654.json
index d5adda1d0d7..95d54906558 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6654.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6654.json
@@ -1 +1 @@
-{"CYTARABINE": 7.938607581413303, "KEYTRUDA": 4.277540214792153, "LEMTRADA": 18.29954473561047, "LEVOFLOXACIN": 5.82542853068188, "SOLIRIS": 7.3629327914664335, "VORICONAZOLE": 28.95326954922581}
\ No newline at end of file
+{"null": 0.6110021031734242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6655.json
index 97c25ca1c6e..c440f5cc6e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6655.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6655.json
@@ -1 +1 @@
-{"SPINRAZA": 278.9977731143591, "null": 1.8023493232929435}
\ No newline at end of file
+{"null": 3.51233967253537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6656.json
index e014ef32f86..41efc9fb5a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6656.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6656.json
@@ -1 +1 @@
-{"BENLYSTA": 5.727665115750488, "ELIQUIS": 1.1499200945846255, "ESMYA": 122.33656821287612, "FENTANYL": 5.280819042523384, "HUMALOG": 1.967484496292496, "OPSUMIT": 8.669934685915337, "PEGASYS": 2.394694919680528, "SPINRAZA": 72.53106069592043, "TREMFYA": 16.049641240564625, "null": 1.3646325137547728}
\ No newline at end of file
+{"CLOPIDOGREL": 13.565513983034974, "ENTRESTO": 10.09415479386784, "JEVTANA": 43.06972406313073, "null": 1.3500589800646416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6657.json
index 32b523417cc..e6b372c6012 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6657.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6657.json
@@ -1 +1 @@
-{"COVID19": 6.910463954165801}
\ No newline at end of file
+{"VAXZEVRIA": 3.632149091269595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6658.json
index 51ea448dd09..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6658.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6658.json
@@ -1 +1 @@
-{"APIXABAN": 2.671425100550385, "BRILIQUE": 14.546583922985786, "CLOPIDOGREL": 18.24911069287091, "ELIQUIS": 19.312829696576863, "ENOXAPARIN": 19.80962190286255, "ESMYA": 30.69483207240664, "FEBUXOSTAT": 48.5525773713977, "HEMLIBRA": 33.57126784887463, "PLAVIX": 9.988297316909538, "RITUXIMAB": 4.991470222230597, "XARELTO": 17.40844868134598, "null": 1.3932312496353043}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6659.json
index 2b6cd2886a5..4d677817413 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6659.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6659.json
@@ -1 +1 @@
-{"SPINRAZA": 469.6356570752501}
\ No newline at end of file
+{"null": 0.9766116568776682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/666.json
index 41828b5e1a2..04dd3bcbac6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/666.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/666.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.5537010337651231, "CLOPIDOGREL": 3.006575658523409, "CRIXIVAN": 28.06281448725047, "ELIQUIS": 5.641196238041681, "NOVOSEVEN": 55.73916270229012, "PLAVIX": 1.6232442091604216, "TASIGNA": 5.013581101586812, "VAXZEVRIA": 1.9607511262791104}
\ No newline at end of file
+{"HUMALOG": 5.502811826039766, "HUMIRA": 11.04194052913834, "XELJANZ": 7.165020752222783, "null": 0.9761630124195084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6660.json
index d3e701d4810..bf3a0119ce8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6660.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6660.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 13.566224474182846, "FENTANYL": 68.12447363244294, "SUFENTANIL": 104.79014404852744, "null": 2.456730492580001}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6661.json
index a727903f49b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6661.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6661.json
@@ -1 +1 @@
-{"BRIDION": 60.408463051357, "COVID19": 1.093349197418317, "DEXAMETHASONE": 40.97070936748767, "FENTANYL": 78.97129346318529, "SPINRAZA": 191.43637376659936}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6662.json
index ba5820ac5a3..fa2e176ed84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6662.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6662.json
@@ -1 +1 @@
-{"ACLASTA": 28.83017076200957, "ADALIMUMAB": 20.61423495256972, "AMINOSALICYLIC": 39.64681039436218, "AVAMYS": 51.7033434624297, "BENLYSTA": 1.219664920672056, "BUDESONIDE": 61.97940338329205, "BUPIVACAINE": 3.299795593688674, "BUPRENORPHINE": 2.166426081191697, "BYETTA": 1.6581784995000068, "CABOMETYX": 1.742292928779191, "CIMZIA": 2.865014836702534, "ELIQUIS": 1.4319569788393125, "ENTYVIO": 1.0358032548970006, "FASLODEX": 1.3866431581636058, "FENTANYL": 2.671830534646184, "HUMALOG": 1.3967307765387582, "HUMIRA": 4.2973966967318935, "PREGABALIN": 28.296959539094143, "SIMPONI": 1.0712968295972856, "SOLIRIS": 1.062547270072744, "SPINRAZA": 120.87952076780572, "SUBOXONE": 13.970137844451523}
\ No newline at end of file
+{"FULVESTRANT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6663.json
index 64447fb8e5a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6663.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6663.json
@@ -1 +1 @@
-{"null": 2.8246314187502346}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6664.json
index 62d95c7e456..b571d5f96ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6664.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6664.json
@@ -1 +1 @@
-{"null": 1.5484537234902955}
\ No newline at end of file
+{"COMIRNATY": 0.7367590589310873, "SPIKEVAX": 1.9945368583202605, "null": 0.5639274422831586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6665.json
index 30454f1207e..83b6b85ce5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6665.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6665.json
@@ -1 +1 @@
-{"BRIDION": 94.8049991961705, "DEXAMETHASONE": 36.59828765358079, "FENTANYL": 67.02332752202292, "SPINRAZA": 231.11594451421843}
\ No newline at end of file
+{"AUBAGIO": 93.90638563192442, "ENTYVIO": 37.39964027356265, "null": 0.1652842167503198}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6666.json
index 9275cfe33ca..5dfb316ae27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6666.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6666.json
@@ -1 +1 @@
-{"AVASTIN": 2.5874098425158985, "CIMZIA": 2.4567204029914484, "CYTARABINE": 4.743904605819446, "ENTYVIO": 8.529521921051762, "FENTANYL": 2.085661934963761, "HUMIRA": 3.142974378260089, "INCIVO": 58.57944069348382, "JARDIANCE": 2.5489897241530137, "NEXAVAR": 1.046997026089656, "PEGASYS": 6.765729653415421, "PEGINTERFERON": 13.737783149482118, "PEGINTRON": 2.199082126005491, "RIBAVIRIN": 4.497240026359802, "SIMPONI": 1.5516833858111594, "STELARA": 1.364455201703047, "STIVARGA": 5.255582445562452, "SUTENT": 6.404359917165865, "VOTRIENT": 3.1426266372805896, "null": 1.2606802109988062}
\ No newline at end of file
+{"ALEMTUZUMAB": 85.77065040140113, "AUBAGIO": 7.2209830878534, "AZACITIDINE": 47.00734851353359, "BENLYSTA": 10.913633692233969, "BUSULFAN": 40.14728292653586, "CARFILZOMIB": 176.82930722414977, "CARMUSTINE": 126.61304747228668, "CELLCEPT": 18.12640361946038, "CICLOSPORIN": 11.73940619695463, "EPIVIR": 38.38209824326554, "RITUXIMAB": 18.656844498237287, "null": 0.1545039784550728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6667.json
index 2e10be0e637..c079965f928 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6667.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6667.json
@@ -1 +1 @@
-{"ADALIMUMAB": 20.477085463132635, "ALIGN": 260.373752025888, "AMINOSALICYLIC": 146.21761997883382, "AVAMYS": 75.78729699646041, "AZATHIOPRINE": 2.036643531196846, "BUDESONIDE": 109.54358055323075, "ENTYVIO": 10.372175913626387, "HUMIRA": 2.8911605061076124, "INCIVO": 3.2245793420937776, "PREGABALIN": 40.00546335312899, "XELJANZ": 1.2850458423581457}
\ No newline at end of file
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6668.json
index 60435c2b2cc..132f18596c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6668.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6668.json
@@ -1 +1 @@
-{"STELARA": 63.96931646068537}
\ No newline at end of file
+{"null": 5.727761688805479}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6669.json
index a83e3e1d231..89888b71c2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6669.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6669.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 14.719613437850914, "EVRA": 333.66787809081507, "FENTANYL": 3.928994117267088, "KENTERA": 266.19442500055175, "null": 11.538176703883272}
\ No newline at end of file
+{"ABACAVIR": 0.9964635855555942, "ABILIFY": 0.186926140489024, "AERIUS": 1.6105396122135072, "AFINITOR": 0.5994054360143893, "ALEMTUZUMAB": 0.720978426919113, "ALIMTA": 0.2946410035394339, "ALOXI": 15.536059121445389, "AMIKACIN": 1.8506792590522805, "AMINOSALICYLIC": 0.6032817316804246, "APIDRA": 0.2927578593114557, "APROVEL": 2.692694845794366, "APTIVUS": 19.5686164861567, "ARANESP": 0.2195405780516889, "ARAVA": 0.3373113401489315, "ASPARAGINASE": 2.2099360541617314, "ATAZANAVIR": 12.4303862812158, "ATEZOLIZUMAB": 2.471010583624879, "ATRIPLA": 0.1321652903092564, "AUBAGIO": 0.3422673999451494, "AVANDIA": 1.6282480843982647, "AVASTIN": 1.3661992398455771, "AZATHIOPRINE": 1.45040016973104, "BARACLUDE": 4.588502279679656, "BETAFERON": 2.5575392497411418, "BIKTARVY": 1.1285910685454168, "BUPRENORPHINE": 0.6757300851040206, "BUSULFAN": 0.6866185259324946, "BYDUREON": 0.2172437955232528, "BYETTA": 1.638999834802348, "CABOMETYX": 1.1545691521693169, "CAELYX": 0.6764861163674518, "CANCIDAS": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/667.json
index 7dee1fd5056..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/667.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/667.json
@@ -1 +1 @@
-{"null": 1.6962176648425369}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6670.json
index f0ee1be02de..8bed1b2bf75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6670.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6670.json
@@ -1 +1 @@
-{"AIMOVIG": 2.807321070644702, "EVRA": 53.11866923087421, "FASLODEX": 2.78276627057596, "FENTANYL": 3.613940079394489, "FLUCELVAX": 27.68251193880776, "FORSTEO": 5.143637701479135, "GARDASIL": 3.547148327329185, "HUMALOG": 1.4470843943084732, "LANTUS": 1.7311013152897534, "PLEGRIDY": 6.107209423305534, "QUTENZA": 43.80814975471984, "SHINGRIX": 6.27996401683862, "TOZINAMERAN": 2.2862823049536014, "TRULICITY": 8.868154149359322, "ZOSTAVAX": 1.7012887611944074, "ZYPADHERA": 7.380180241670926, "null": 1.871337847969761}
\ No newline at end of file
+{"null": 1.3534383220088049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6671.json
index b6706be12cc..b5632c7d63b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6671.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6671.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 3.601808732175522, "BEXSERO": 14.268787928159856, "BRIDION": 15.29805648294015, "BRINTELLIX": 4.60572362910094, "BUDESONIDE": 1.328900637623055, "BUPIVACAINE": 12.84518811127172, "BUPRENORPHINE": 1.336947113149273, "BUSULFAN": 11.65685254376015, "CIRCADIN": 237.60224187662067, "COSENTYX": 1.352395899720179, "CRESEMBA": 27.39448415324466, "DEXDOR": 90.26655160878968, "DEXMEDETOMIDINE": 72.59612084088424, "ENTYVIO": 6.087613074228484, "FYCOMPA": 6.763873098312874, "GARDASIL": 2.633318660205244, "HEMANGIOL": 229.77071380582444, "ICLUSIG": 15.700536603397218, "INFANRIX": 7.266874030610229, "LATUDA": 5.531422011277158, "LEVETIRACETAM": 3.3369634952941434, "MIDAZOLAM": 4.788238682462222, "NIMENRIX": 2.834225076393344, "NOXAFIL": 9.057095832837096, "PREVENAR": 11.787694360646636, "PROPRANOLOL": 6.425338342645916, "ROTATEQ": 21.06347028043164, "SHINGRIX": 19.92911847991682, "SLENYTO": 129.40971429495238, "TWINRIX": 16.19330497497042, "ZOSTAVAX": 1.4366797470079755, "null": 1.951529458972613}
\ No newline at end of file
+{"ACLIDINIUM": 100.8431385813956, "AFINITOR": 1.2711251820079403, "ANORO": 5.675143719615152, "APTIVUS": 51.086931422449055, "ASPARAGINASE": 3.580166422718817, "AVANDIA": 1.3118546799109208, "BYDUREON": 2.781843868918307, "BYETTA": 30.374807251659902, "CASPOFUNGIN": 7.665421988098072, "COMIRNATY": 0.015365251725304, "CYTARABINE": 1.975099270609408, "ELIQUIS": 0.733700825243204, "EXJADE": 1.5266735949051826, "JANUMET": 2.251596411405714, "JANUVIA": 4.142499603626009, "KEPPRA": 0.8821025171955196, "KEYTRUDA": 1.321671835721358, "MICARDIS": 3.599469362675688, "NEXAVAR": 6.9100771723361385, "PLAVIX": 1.2334002550937353, "STIVARGA": 4.1565007985323765, "SUTENT": 0.4002332093714089, "TOZINAMERAN": 0.1140035797250323, "VAXZEVRIA": 0.0364440369601369, "VFEND": 4.736084577014103, "VOTRIENT": 2.8791658437633068, "null": 2.554480231050181}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6672.json
index 52ae3e30897..e485ccdaf65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6672.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6672.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.476840969105917, "ACTRAPID": 3.961530675818505, "APIDRA": 5.531902959028437, "APROVEL": 2.721008239155132, "BONVIVA": 4.101416489412935, "BRIDION": 1.2369035014169585, "BRINTELLIX": 1.301415818094121, "BUMETANIDE": 2.331609469460284, "BYDUREON": 1.5175255227224298, "CLOPIDOGREL": 4.830460958153646, "DAPTOMYCIN": 15.009462586872033, "DULOXETINE": 1.2722674063649726, "EMEND": 2.068666556813258, "EMPAGLIFLOZIN": 1.2502400386652452, "ESMYA": 14.64511411024511, "ESOMEPRAZOLE": 1.478942187759193, "EVRA": 3.2448183376503827, "GLIBENCLAMIDE": 2.712001718556157, "HUMALOG": 2.087105649241942, "IBUPROFEN": 1.722795999297765, "INCRUSE": 1.2153328275615791, "INSULIN": 1.6277779169783375, "IRBESARTAN": 1.920536088143865, "JANUMET": 1.79173354026138, "KEPPRA": 1.479013600779459, "LANTUS": 12.107783947080874, "LATUDA": 6.974510321680538, "LEVEMIR": 2.470478097143442, "LEVETIRACETAM": 1.7060481752117496, "LEVODOPA": 2.644137164702144, "MAVENCLAD": 2.096463515476069, "MENVEO": 1.4794557228773977, "MEPOLIZUMAB": 2.2545662490435574, "MIDAZOLAM": 1.868614721047376, "NAGLAZYME": 3.5445046443729047, "NEVANAC": 11.69880648177743, "NOT": 2.6489762917871937, "NOVORAPID": 2.517178850624717, "NOXAFIL": 2.076004331048994, "PLAVIX": 1.3207260705529205, "PRASUGREL": 23.65792598113279, "ROACTEMRA": 1.451782810444746, "SHINGRIX": 1.277003086629831, "SIMPONI": 1.291476137107232, "STALEVO": 1.8270458288343143, "TICAGRELOR": 3.3964352939835822, "TOUJEO": 1.8230623766587624, "TOVIAZ": 1.0627932313225614, "UNSPECIFIED": 5.682825623944992, "VIAGRA": 1.3968645426860915, "VIMPAT": 2.1304216253860155, "XARELTO": 1.5693989105694592, "null": 3.675016194065194}
\ No newline at end of file
+{"LEVEMIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6673.json
index ace5cf9bb43..c8f5b73a6b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6673.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6673.json
@@ -1 +1 @@
-{"AIMOVIG": 7.403961965885593, "AVAMYS": 10.035110074718933, "EBIXA": 92.2203453366499, "EVENITY": 30.2334681074962, "IBRANCE": 4.6872605400474265, "IBUPROFEN": 15.276899283236482, "MACITENTAN": 128.55663112788406, "XELJANZ": 3.620536614562346, "null": 1.726937071126384}
\ No newline at end of file
+{"null": 1.8799987942868013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6674.json
index c45cec5b017..0367717b03e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6674.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6674.json
@@ -1 +1 @@
-{"TRELEGY": 18.5683780387856, "null": 3.88628898007962}
\ No newline at end of file
+{"ABILIFY": 16.494457985737277, "BUPRENORPHINE": 21.87128982870628, "BUVIDAL": 200.11772087021816, "COMBIVIR": 7.267834109154724, "HUMALOG": 3.3853661803101547, "INSULIN": 5.943720447108028, "KEPPRA": 3.5264226968335826, "LANTUS": 2.950018263934024, "LEVEMIR": 41.36354391916744, "OPIOIDS": 117.36398677284554, "SUBOXONE": 80.40526902862044, "null": 1.1519002581863391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6675.json
index eae7bbd5dd2..9dcdd46bc58 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6675.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6675.json
@@ -1 +1 @@
-{"FIASP": 484.1838787489507, "NOVORAPID": 16.30443179020188, "null": 3.2285115701860283}
\ No newline at end of file
+{"COMIRNATY": 0.5552461789524855, "null": 0.9559290879659368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6676.json
index 73c68fc625d..9c088c675a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6676.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6676.json
@@ -1 +1 @@
-{"AERIUS": 6.906315116320731, "APROVEL": 5.257459566306882, "AVAMYS": 2.9854771737362187, "AZATHIOPRINE": 2.416652703066004, "BEDAQUILINE": 3.0077993634137505, "BENLYSTA": 25.63064723453765, "BETMIGA": 7.985409058127021, "BRIVIACT": 27.22052828453979, "CHAMPIX": 5.336997095177058, "CIMZIA": 8.024197737829825, "COMTAN": 17.015426290426387, "ENTRESTO": 1.0788851324316406, "IKERVIS": 39.08392780175632, "JAKAVI": 1.0864030567387897, "JANUMET": 2.6374662888767424, "JANUVIA": 1.37266190997588, "KEPPRA": 6.011075583177427, "LEVETIRACETAM": 1.257539558384981, "LONSURF": 42.75693475670063, "NUCALA": 9.039400450353344, "OMALIZUMAB": 2.810760376612675, "OZEMPIC": 16.396631808839434, "SIMPONI": 3.240605375659636, "STELARA": 1.1034767408877757, "TREMFYA": 7.886806890861887, "VIMPAT": 6.260828099343911, "XTANDI": 2.802395357476865, "null": 2.98729263941848}
\ No newline at end of file
+{"AIMOVIG": 4.727488376977303, "BONVIVA": 25.82526582301634, "COMIRNATY": 0.3298546465271099, "ELIQUIS": 1.2533008719860652, "IBRANCE": 4.293373092637439, "SPIKEVAX": 0.2445444494132418, "SUTENT": 4.672011813112553, "TELMISARTAN": 47.529180325284045, "TOZINAMERAN": 0.8726219437653369, "VAXZEVRIA": 0.0853406630851155, "XELJANZ": 1.8624142345197685, "null": 1.0792549107994047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6677.json
index 38a11f756c7..e2eba2b114f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6677.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6677.json
@@ -1 +1 @@
-{"BIKTARVY": 29.42146536340325, "ELIQUIS": 4.029400366951027, "null": 3.046219421583188}
\ No newline at end of file
+{"ANAKINRA": 9.209673671888224, "ATRIPLA": 16.896515538322188, "AZATHIOPRINE": 11.629919927165387, "COMIRNATY": 0.0585442397629959, "ELIQUIS": 1.573954564430013, "FORSTEO": 3.038616370650522, "STRIBILD": 9.851149821781922, "SUBOXONE": 5.823970950528313, "TRUVADA": 12.156778381114195, "null": 0.5465955493585427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6678.json
index 8c206fe46e8..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6678.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6678.json
@@ -1 +1 @@
-{"null": 5.897460791394173}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6679.json
index 1393e41a9d3..33cd0b9d32e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6679.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6679.json
@@ -1 +1 @@
-{"null": 28.410666566280582}
\ No newline at end of file
+{"null": 0.4427496670823753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/668.json
index 12e1b0a8588..0c15906fe6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/668.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/668.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 1.2704060955385224, "ANORO": 94.0594474118258, "APIXABAN": 13.01060907744372, "ARANESP": 1.2494008731478226, "AVANDAMET": 44.49856676448125, "AVANDIA": 29.9932414377477, "AZATHIOPRINE": 6.047843027211649, "BOSULIF": 3.1740392819132848, "BRILIQUE": 1.63886846346867, "BYETTA": 5.57568813475133, "CICLOSPORIN": 2.2435332283671205, "CLOPIDOGREL": 1.82736645384878, "DOCETAXEL": 1.150982486030146, "DULOXETINE": 1.834460265302498, "ELIQUIS": 1.1607339959510716, "ENTRESTO": 1.94040861919125, "EXFORGE": 1.8967387768281392, "EXJADE": 1.1459130390432826, "FORSTEO": 1.341335560583472, "HUMALOG": 1.7733626707919536, "IBUPROFEN": 1.3093464742500145, "ICLUSIG": 6.599810202144397, "INSULIN": 1.6206934674651294, "JANUMET": 5.585314612301204, "JANUVIA": 4.084677463673096, "KALETRA": 1.2995698161304656, "NILOTINIB": 8.397776624493467, "OPTIMARK": 2.02031240214266, "PLAVIX": 1.1729617111276285, "PREGABALIN": 3.53206336569775, "RINVOQ": 1.2651465867817628, "ROSIGLITAZONE": 25.98107655929585, "SPRYCEL": 1.3818219689073343, "TASIGNA": 80.4653115628525, "TESTOSTERONE": 10.723714771519749, "ZOMETA": 9.835765219158038, "ZOSTAVAX": 3.139044374566043}
\ No newline at end of file
+{"OMALIZUMAB": 185.67252581782108, "null": 0.50767180939712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6680.json
index 98dd4b95e56..cfe57863fac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6680.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6680.json
@@ -1 +1 @@
-{"null": 3.457645315486185}
\ No newline at end of file
+{"LEVODOPA": 617.832767470861, "null": 1.9485308526121072}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6681.json
index d0e9fae7269..7891d5b06f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6681.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6681.json
@@ -1 +1 @@
-{"null": 7.229322137377884}
\ No newline at end of file
+{"KEPPRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6682.json
index 2965d99036f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6682.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6682.json
@@ -1 +1 @@
-{"null": 6.115388537611228}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6683.json
index 0853417934c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6683.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6683.json
@@ -1 +1 @@
-{"COAPROVEL": 14.589136290493936, "EXFORGE": 6.306453795668079, "FIASP": 60.56367525498494, "JANUMET": 5.026377358849203, "NEVANAC": 77.60008461597022, "NOVORAPID": 8.00412571229209, "VELTASSA": 27.22284756317718, "VICTOZA": 6.474242149881435, "null": 4.223533455697868}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6684.json
index ddb79e5cf36..d89cd5b70e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6684.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6684.json
@@ -1 +1 @@
-{"null": 4.655308371133672}
\ No newline at end of file
+{"null": 0.5447738916505026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6685.json
index 5f2b46b644b..f3d9ac3b98a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6685.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6685.json
@@ -1 +1 @@
-{"AIMOVIG": 23.80309226130351, "LEVEMIR": 20.14782096978226, "OLANZAPINE": 14.089062967658434, "SAXENDA": 12.65069974537242, "null": 1.844118805382164}
\ No newline at end of file
+{"null": 1.7303640841198316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6686.json
index 1215cf84d91..06fa15be930 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6686.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6686.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.4588680516119032, "ADEFOVIR": 22.58273994844667, "ANORO": 8.610980730373356, "APIDRA": 8.971059113318463, "AVAMYS": 6.145904474039615, "BENLYSTA": 4.982124344830921, "COMTAN": 6.956087761267162, "EVRA": 35.10255332432735, "HEPSERA": 3.57557203930012, "INCRUSE": 12.419809605101712, "INFERGEN": 19.630874306222, "INSULIN": 1.701034786696216, "INSUMAN": 8.109223304435012, "INTEGRILIN": 4.992649438773675, "KENTERA": 13.701573838435705, "LANTUS": 15.815190102846028, "NIMENRIX": 1.041031856338745, "NOVORAPID": 1.0178604745622266, "NUCALA": 3.6156508368937774, "RELVAR": 30.238638022036778, "REVINTY": 50.18569025613216, "ROACTEMRA": 1.0313488463117335, "SIMPONI": 1.024574184848916, "SOVALDI": 2.159330908377829, "STALEVO": 20.89472713737045, "STELARA": 1.0483709840846818, "TRELEGY": 20.816183665126744, "TREMFYA": 3.3616390902896325, "TWINRIX": 10.298596695916508, "VIAGRA": 1.1159145289994576, "null": 5.608788608018839}
\ No newline at end of file
+{"null": 0.3842030418334339}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6687.json
index d654523ea4d..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6687.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6687.json
@@ -1 +1 @@
-{"null": 4.292195308414041}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6688.json
index b53ce235030..88937481f8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6688.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6688.json
@@ -1 +1 @@
-{"null": 2.840853036468754}
\ No newline at end of file
+{"COMIRNATY": 0.3508923314915578, "null": 1.015120923233671}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6689.json
index 0d0481aa932..f0f4278f60d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6689.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6689.json
@@ -1 +1 @@
-{"LEVEMIR": 17.11373965462868, "NEVANAC": 141.15257464816798, "NOVORAPID": 267.482597579064, "null": 2.215441943306689}
\ No newline at end of file
+{"XELJANZ": 21.032903576104804, "null": 0.4775366109396853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/669.json
index 56857b2629d..69e7f14c5a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/669.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/669.json
@@ -1 +1 @@
-{"ACTRAPID": 16.767488677491823, "ANORO": 134.89782747636536, "APIXABAN": 21.80719611464464, "ARIPIPRAZOLE": 5.499371314830549, "AVANDAMET": 51.45619721533965, "AVANDIA": 40.77317616096587, "AZATHIOPRINE": 7.776722063299803, "BUMETANIDE": 45.42836115240488, "BUPRENORPHINE": 3.374393736114491, "BYETTA": 7.340670388812847, "CLOPIDOGREL": 2.121391044178571, "COMBIVIR": 3.210630654223092, "DULOXETINE": 6.049461304118168, "ENTRESTO": 1.7984539858592068, "ESBRIET": 4.78500364079098, "ICLUSIG": 4.056785561356703, "IRBESARTAN": 3.5859000766069, "JANUMET": 6.8364671189082085, "JANUVIA": 7.126013386007306, "OLANZAPINE": 2.2989359988665967, "PLAVIX": 1.3138066536982973, "PREGABALIN": 3.757076249431161, "TASIGNA": 6.380077641824245, "ZOSTAVAX": 7.703860793763111, "ZYPREXA": 1.28159340881802}
\ No newline at end of file
+{"JARDIANCE": 33.61534127907508, "SPIKEVAX": 4.3863425035514005, "null": 0.7889979766615597}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6690.json
index fb2f90d2c75..6ba39d237e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6690.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6690.json
@@ -1 +1 @@
-{"null": 2.611291489515862}
\ No newline at end of file
+{"ADALIMUMAB": 6.169604752142789, "ARAVA": 8.046227968647832, "CICLOSPORIN": 5.496814956601756, "COMIRNATY": 0.5286994954525622, "COSENTYX": 59.33275787265174, "VAXZEVRIA": 0.244831643443166, "null": 0.4646109570280096}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6691.json
index 287a2881f5f..12ff8cc8e3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6691.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6691.json
@@ -1 +1 @@
-{"EYLEA": 11.976672147455483, "SILDENAFIL": 122.30050970217188, "null": 3.4049457148235858}
\ No newline at end of file
+{"ANAKINRA": 183.133100637, "ARAVA": 4.161411677282365, "CIMZIA": 10.137806650864336, "ENBREL": 4.517778103469709, "FORSTEO": 6.511616270248247, "RINVOQ": 14.365386117708816, "SIMPONI": 15.031719347575448, "TRUVADA": 5.742276368623741, "null": 0.4492619848140083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6692.json
index 37cd036d9d2..3b89c804b64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6692.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6692.json
@@ -1 +1 @@
-{"null": 20.440090127758925}
\ No newline at end of file
+{"FAMPYRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6693.json
index fb5928144b1..7bec1919961 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6693.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6693.json
@@ -1 +1 @@
-{"COAPROVEL": 407.8546500435292, "null": 4.092058684049487}
\ No newline at end of file
+{"CICLOSPORIN": 1.708076592073286, "COMIRNATY": 0.0745424202360583, "DULOXETINE": 9.86700866104979, "OPTIMARK": 465.8843764682989, "null": 1.2998116470527088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6694.json
index 97d80ec1ebf..461a1beba20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6694.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6694.json
@@ -1 +1 @@
-{"HUMIRA": 19.590340374175348, "MIDAZOLAM": 44.27052488058702, "null": 2.362693008173615}
\ No newline at end of file
+{"ABATACEPT": 23.2061020357899, "ADALIMUMAB": 66.29193317804193, "ANAKINRA": 14.327017750745938, "ARAVA": 1.3409864647893808, "ENBREL": 10.222374383493202, "METHOTREXATE": 7.3786347981135645, "XELJANZ": 4.924543241345287, "null": 0.3056021691715723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6695.json
index da472d3d21b..58520581a24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6695.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6695.json
@@ -1 +1 @@
-{"FENTANYL": 13.172184782434034, "LANTUS": 4.233259282086727, "PEGASYS": 2.4270704554170552, "PLAVIX": 24.487052627680413, "SILDENAFIL": 88.98924937323102, "VIAGRA": 11.3709334368447, "null": 2.142719995295475}
\ No newline at end of file
+{"ABATACEPT": 5.580822404097319, "ADALIMUMAB": 5.662995566305843, "ARAVA": 5.753669442414161, "ATRIPLA": 1.11362539111119, "BELIMUMAB": 69.43455530613893, "BENLYSTA": 3.1363259744576464, "CIMZIA": 1.4225657277130754, "CLOPIDOGREL": 1.1526395341284836, "COMIRNATY": 0.0999427523136451, "CYMBALTA": 1.2409594280849323, "ELIQUIS": 0.5863122254034794, "ENBREL": 0.9052310213450514, "ENOXAPARIN": 7.837846675993964, "EXFORGE": 2.020315567184119, "FORSTEO": 4.720388649758985, "GARDASIL": 2.0492379273751333, "HUMALOG": 1.1625596216500258, "IBRANCE": 0.4764909202619405, "KEPPRA": 1.2080751861310073, "LAMIVUDINE": 7.401791026363712, "LANTUS": 1.3840480819319447, "LEFLUNOMIDE": 9.479033920455276, "LEVETIRACETAM": 1.9125044350178164, "METHOTREXATE": 1.157410439247119, "OMALIZUMAB": 4.119463676719956, "ORENCIA": 24.99637547874075, "PEGASYS": 0.5294264224505273, "RINVOQ": 3.77414152855097, "SIMPONI": 2.959126473205028, "SPIKEVAX": 0.1049309982967092, "SPINRAZA": 19.576110150056387, "STRIBILD": 0.9294196811702462, "SUBOXONE": 1.544837554070008, "TOZINAMERAN": 0.3294584201492496, "TRUVADA": 0.8418021547969856, "VAXZEVRIA": 0.1119050700370749, "VIAGRA": 2.0967742615893536, "XELJANZ": 5.645951220706646, "XOLAIR": 1.4053360768506218, "XTANDI": 1.28246756878268, "XYREM": 5.122601361281031, "ZOSTAVAX": 1.2325091933854164, "null": 1.08417801308498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6696.json
index e7e0c487b30..a6734e20384 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6696.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6696.json
@@ -1 +1 @@
-{"NEVANAC": 183.744377120215, "null": 9.265826238224996}
\ No newline at end of file
+{"ABATACEPT": 4.445238767926507, "ABILIFY": 5.746260228558585, "ADALIMUMAB": 2.6817215856208683, "ANAKINRA": 5.507273436891977, "ARAVA": 1.5831773441563748, "BEXTRA": 30.172665544142905, "CICLOSPORIN": 0.6915979922052761, "CIMZIA": 3.538957970803576, "COMIRNATY": 0.4389682565478531, "COSENTYX": 1.6838925857136475, "CYMBALTA": 0.4412122311507256, "EMPAGLIFLOZIN": 9.595378390794128, "ENBREL": 3.557999372806435, "GARDASIL": 0.7099180372400659, "HUMIRA": 5.215604669545476, "KEYTRUDA": 0.7358652848868867, "LEFLUNOMIDE": 11.502311676159648, "METHOTREXATE": 5.321229302866509, "ORENCIA": 35.47490257158812, "RINVOQ": 3.7176903263129137, "ROACTEMRA": 2.022844472369268, "SHINGRIX": 0.8407865904720458, "SIMPONI": 2.7842994228847484, "SPIKEVAX": 0.2745605081276784, "STELARA": 0.9896604305863932, "SUTENT": 0.2669153052396109, "TOZINAMERAN": 0.4693720975924561, "TRUVADA": 0.3968679455034636, "VAXZEVRIA": 0.1339414784125345, "XELJANZ": 4.045972739242057, "ZOSTAVAX": 1.1143958604913782, "null": 1.8090536860999464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6697.json
index 1b3ef039b7e..866ac2ed2ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6697.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6697.json
@@ -1 +1 @@
-{"FIASP": 192.5742350082225, "null": 5.278284416263158}
\ No newline at end of file
+{"GARDASIL": 11.915493764137414, "null": 2.329003629215115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6698.json
index 15836c7d4d5..45edb5aaf1f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6698.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6698.json
@@ -1 +1 @@
-{"null": 3.0938723142390154}
\ No newline at end of file
+{"ABATACEPT": 2.6461823404171314, "ADALIMUMAB": 1.7715139433403817, "ADVATE": 24.11801714283509, "AFINITOR": 1.4018036606572482, "ANAKINRA": 10.19233519792376, "ARAVA": 4.748670391265248, "ATRIPLA": 1.941626183834832, "AUBAGIO": 2.294290256694181, "BUPRENORPHINE": 1.2394958018036348, "BYDUREON": 1.084040815959881, "BYETTA": 1.0280150746889354, "CIMZIA": 2.687476638478505, "COMIRNATY": 0.0604484497072653, "COSENTYX": 1.2110742372452947, "CYMBALTA": 0.8349878403123904, "ELIQUIS": 2.044743262107385, "ENBREL": 19.635145082222294, "ENTRESTO": 1.1384400656272244, "FAMPYRA": 2.0171236454140304, "FASLODEX": 1.6078371882391471, "FIRDAPSE": 3.9161525349876736, "FORSTEO": 2.053027434450842, "GARDASIL": 0.8028577926197338, "HEMLIBRA": 13.858352433988214, "HUMALOG": 3.175165744592051, "HUMIRA": 6.349665936856559, "IBRANCE": 2.2938926367442845, "IBUPROFEN": 0.9003758663816845, "INSULIN": 1.171523984000636, "JARDIANCE": 0.3857675019475543, "KEPPRA": 1.024413102278174, "KOVALTRY": 67.81377526866912, "LANTUS": 2.4033149759038936, "LYRICA": 2.0958765396681365, "METHOTREXATE": 1.4215570097909231, "NUCALA": 1.3955858456519656, "OMALIZUMAB": 1.7855743646831022, "OPSUMIT": 0.962690781833966, "PAIN": 330.36144888742234, "REVATIO": 1.999681214815903, "SIMPONI": 1.9118558702032973, "SPIKEVAX": 0.1182387369656744, "STELARA": 0.4563503280791934, "STRIBILD": 1.2774412833323403, "SUBOXONE": 4.029592961071299, "SUTENT": 0.8975237937797904, "TOVIAZ": 2.7403460407402047, "TOZINAMERAN": 0.4582157395269939, "TRUVADA": 1.0937600119689506, "VAXZEVRIA": 0.0675777930213036, "VIAGRA": 1.9863827331578048, "VICTOZA": 1.3281521748318008, "XELJANZ": 6.665940587540864, "XOLAIR": 1.0435106422615117, "XTANDI": 0.5383747870956164, "XYREM": 4.204518378548572, "ZOSTAVAX": 3.482734949837657, "null": 0.9557533093163876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6699.json
index 6e329cb0fb5..e315719fb5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6699.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6699.json
@@ -1 +1 @@
-{"null": 3.345147135380988}
\ No newline at end of file
+{"COMIRNATY": 0.4107027972380814, "OPTIMARK": 14.767543283681883, "TOZINAMERAN": 0.969858333122684, "null": 1.2479329024796038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/67.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/67.json
index 03fa7f0b1ac..c1a089eaedd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/67.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/67.json
@@ -1 +1 @@
-{"ICLUSIG": 46.27348328858969, "null": 1.130256808323252}
\ No newline at end of file
+{"ARAVA": 0.2737234058730221, "AUBAGIO": 1.5872829504201278, "CIMZIA": 2.4104496336379198, "COMIRNATY": 0.3229492500636067, "ENOXAPARIN": 7.398702397480677, "EPIVIR": 13.029016481270984, "GARDASIL": 1.9056172244196736, "GONALF": 144.45015550521677, "KEPPRA": 4.8974764052425614, "LANTUS": 1.1605462377183269, "SAXENDA": 5.70146086621288, "SIMPONI": 1.2789203279358672, "SPIKEVAX": 0.105976039942858, "TAMIFLU": 3.115044874824876, "VAXZEVRIA": 0.1938504537739639, "ZYPREXA": 1.897944676408417, "null": 2.3717093911966223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/670.json
index 6b6abcc58c3..d7003eb8068 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/670.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/670.json
@@ -1 +1 @@
-{"AIMOVIG": 5.793762369576544, "AVANDIA": 1.5725447802966062, "BRIDION": 41.88225720413606, "BUPIVACAINE": 7.463881350510869, "CAPECITABINE": 12.216730301039656, "ENBREL": 2.431936267398563, "FENTANYL": 6.20954473958047, "MIDAZOLAM": 6.9711217604801305, "TASIGNA": 3.099875018838641, "null": 4.164066145162414}
\ No newline at end of file
+{"null": 1.1654417738127898}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6700.json
index e5ed4816546..3c39c45957c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6700.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6700.json
@@ -1 +1 @@
-{"ACE": 40.20452458043525, "ANORO": 3.132968610967063, "APIDRA": 2.1700914004896266, "BYDUREON": 2.939158479693294, "BYETTA": 1.1053935962952095, "CLOPIDOGREL": 1.396895395698538, "DAPTOMYCIN": 42.9960251449162, "ELIQUIS": 1.3611854586210528, "ENTYVIO": 2.6906942033592443, "FIASP": 4.511898013930061, "FLUTICASONE": 30.41188208519931, "HUMALOG": 6.752393443766357, "IBRANCE": 4.095536287614363, "INCRUSE": 5.543423532013192, "INSULIN": 1.13739107122558, "JANUMET": 2.4208658886875427, "JEVTANA": 6.758245194668755, "KEPPRA": 1.7830104528483222, "LANTUS": 1.480068773366637, "LEVEMIR": 4.630873659602108, "NOVOMIX": 39.40436118860804, "NOVORAPID": 2.2251275871619924, "PANTOPRAZOLE": 1.739170953115386, "RAPAMUNE": 3.1069162988031027, "RELVAR": 5.725191939227428, "REVATIO": 2.405952606024619, "RINVOQ": 1.1537857411314398, "SUBOXONE": 1.3864929527482186, "SUTENT": 1.1274002507000178, "TAMIFLU": 1.2108172192582218, "TOUJEO": 2.7433617618824675, "TOVIAZ": 5.17099796717938, "TRELEGY": 4.224463027910352, "TRESIBA": 5.750628610143592, "VEMLIDY": 16.39437735989556, "VFEND": 2.652762511189472, "VIAGRA": 3.609722227177732, "XELJANZ": 4.14149329496209, "null": 3.193394836967029}
\ No newline at end of file
+{"ADALIMUMAB": 4.350710000482538, "ARAVA": 5.151728547941032, "ENBREL": 30.53168598296857, "null": 1.894625031156298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6701.json
index 210f12a88a5..d72b5ceec83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6701.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6701.json
@@ -1 +1 @@
-{"IBRANCE": 5.772013421315129, "XELJANZ": 10.82425487424132, "null": 2.52699458851551}
\ No newline at end of file
+{"ARAVA": 3.154657351955785, "CIMZIA": 2.5447231649887745, "COMIRNATY": 0.7705997964930895, "ENBREL": 3.236007646610801, "GARDASIL": 4.4892970446945055, "OPTIMARK": 16.027510860816882, "RINVOQ": 11.05575341248968, "SIMPONI": 3.5446852140759413, "SPIKEVAX": 0.8940375890912682, "TOZINAMERAN": 2.068772020517694, "VAXZEVRIA": 1.0652165925120838, "XELJANZ": 4.297236570338184, "null": 0.5840195117407057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6702.json
index c79b5705aa3..d9b8f653332 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6702.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6702.json
@@ -1 +1 @@
-{"CIMZIA": 13.240319325083757, "FASENRA": 43.56567503761844, "null": 1.7615821240307266}
\ No newline at end of file
+{"ARAVA": 0.7243117595039537, "BIKTARVY": 9.535371885678456, "CLOPIDOGREL": 2.1035480486616303, "COMIRNATY": 0.4661980060816016, "COSENTYX": 3.2001120078423546, "CYMBALTA": 21.73929111585515, "DULOXETINE": 14.11764451627266, "ENBREL": 3.3578727614982995, "GARDASIL": 3.4018527997399164, "HUMIRA": 14.069619736949464, "LEVOFLOXACIN": 4.901754051696568, "SPIKEVAX": 0.3378891800234871, "STELARA": 2.37739441653124, "TOZINAMERAN": 2.2290878304552777, "VAXZEVRIA": 0.599598788483235, "XELJANZ": 3.4600512196386384, "null": 0.7842663010211496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6703.json
index 0f468ab8a39..5478f9a3de4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6703.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6703.json
@@ -1 +1 @@
-{"null": 3.0915894918603004}
\ No newline at end of file
+{"UPADACITINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6704.json
index 5f4e86171cf..1eb9da396cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6704.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6704.json
@@ -1 +1 @@
-{"null": 5.551760277563229}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6705.json
index b2e7b6bb632..caa38470670 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6705.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6705.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"CUBICIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6706.json
index 731de28652a..6081d7a428f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6706.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6706.json
@@ -1 +1 @@
-{"AUBAGIO": 16.149579734186496, "CIMZIA": 2.857514498487939, "ELIQUIS": 1.761733718514389, "ENTRESTO": 1.467963303586436, "EPCLUSA": 7.067992508614373, "FAMPYRA": 35.238367265280324, "FULVESTRANT": 6.374283779589493, "GALAFOLD": 44.89261774555358, "IBRANCE": 14.816397952362763, "INLYTA": 6.142552611668178, "LIXIANA": 5.319145280218994, "PLEGRIDY": 6.086868225802203, "SUBOXONE": 2.003271093613406, "TOUJEO": 6.405887570616123, "TRELEGY": 4.525542566580455, "VELTASSA": 9.88908215681454, "XELJANZ": 29.36672245036584, "ZEJULA": 37.735137892659885, "null": 1.741318624812369}
\ No newline at end of file
+{"ARAVA": 3.845305753883379, "HUMIRA": 59.66092118885856, "LEFLUNOMIDE": 153.61749085687117, "null": 0.2307556459259619}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6707.json
index c48b01c48bc..a9ee3c848fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6707.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6707.json
@@ -1 +1 @@
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\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6708.json
index 5483aa95bc1..bb41ea85716 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6708.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6708.json
@@ -1 +1 @@
-{"null": 1.736640177686496}
\ No newline at end of file
+{"ARAVA": 11.199492756394845, "SIMPONI": 22.55073172401233, "null": 0.4492116245353612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6709.json
index ed7c44167ff..1b2688d10ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6709.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6709.json
@@ -1 +1 @@
-{"GREPID": 480.6615881764384, "null": 11.653632592534928}
\ No newline at end of file
+{"ABACAVIR": 12.71982779552135, "ABATACEPT": 10.142075487750692, "ABILIFY": 0.1170830865596722, "ACETAMINOPHEN": 11.752481310346198, "ACLASTA": 2.5442527299246827, "ADALIMUMAB": 5.042387765396186, "ADCIRCA": 0.655109885547399, "ADEMPAS": 0.7285700052963106, "ADVATE": 3.1137597639486088, "AFINITOR": 0.6851782328378504, "AIMOVIG": 0.2900211873515167, "ALEMTUZUMAB": 0.6755829473453391, "AMBRISENTAN": 1.2445423335660797, "AMINOSALICYLIC": 0.6102977652907687, "ANAKINRA": 13.475438026954969, "APIDRA": 0.2945505368187712, "APREMILAST": 5.527664314302268, "APREPITANT": 1.328474794032794, "ARANESP": 0.1450867318375449, "ARAVA": 14.2544577443333, "ATRIPLA": 0.0413120420992274, "AUBAGIO": 0.3780937494039489, "AVANDAMET": 0.5223114008506505, "AVANDIA": 0.5616436161119797, "AZATHIOPRINE": 2.193897666041273, "BENLYSTA": 1.6442573993558138, "BETMIGA": 2.239649734535078, "BIKTARVY": 0.214751725871887, "BONVIVA": 0.9125331053970824, "BOSENTAN": 1.3218187011318892, "BOTULINUM": 0.5317646918396194, 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0.2617730411444328, "null": 0.4878483427846685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/671.json
index 9277bd6a455..65723140e12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/671.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/671.json
@@ -1 +1 @@
-{"VELTASSA": 291.3353824941928}
\ No newline at end of file
+{"null": 0.8553834483359593}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6710.json
index 784f0fc968b..522f11b95b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6710.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6710.json
@@ -1 +1 @@
-{"FIASP": 1916.530692084404}
\ No newline at end of file
+{"ADALIMUMAB": 1.0281225789882504, "CIMZIA": 2.267299540860866, "COMIRNATY": 1.18165867487757, "ENBREL": 6.113449167434034, "SPIKEVAX": 0.621387702812942, "TOZINAMERAN": 0.9998140093718004, "VAXZEVRIA": 0.9641103315415098, "null": 1.0016880430204194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6711.json
index 7a2c12c4ca1..3a82c847214 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6711.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6711.json
@@ -1 +1 @@
-{"CHAMPIX": 26.225322480846494, "null": 3.906261862577389}
\ No newline at end of file
+{"BUDESONIDE": 5.545544177368384, "CHAMPIX": 4.025293448344396, "FENTANYL": 4.73366634236642, "MELATONIN": 46.46521269425487, "OLANZAPINE": 7.769218796565812, "PEGASYS": 1.752948477604729, "null": 3.491087589580632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6712.json
index 57e7c1b0f26..7fd9a227cf6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6712.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6712.json
@@ -1 +1 @@
-{"null": 2.40622094449741}
\ No newline at end of file
+{"AVANDIA": 9.058979089733969, "CLOPIDOGREL": 10.421901348256585, "COMIRNATY": 0.1328180205059421, "null": 1.5821250721374358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6713.json
index 8fa2ab19690..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6713.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6713.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.917535318493809, "ARAVA": 9.402989570418708, "null": 2.2974437054956462}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6714.json
index 382b34e9be0..23ed3c2822b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6714.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6714.json
@@ -1 +1 @@
-{"ELIQUIS": 3.4804982310872354, "HUMIRA": 8.52569055747612, "SIMPONI": 5.478927097540825, "STELARA": 7.957760447998941, "TREMFYA": 23.86849139802609, "null": 2.906603184764656}
\ No newline at end of file
+{"AFINITOR": 3.0819567821269693, "AVASTIN": 9.688102969826112, "COMIRNATY": 0.6494387371806382, "ELIQUIS": 1.7728446985284956, "GONALF": 70.29657831827883, "NOVOSEVEN": 71.44507794814716, "ONCASPAR": 38.610380459476936, "SPIKEVAX": 0.3493917937640324, "TOZINAMERAN": 0.5924890304612838, "VAXZEVRIA": 1.7263628480003932, "null": 0.6504504820235479}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6715.json
index a67505187f4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6715.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6715.json
@@ -1 +1 @@
-{"null": 6.541596807880673}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6716.json
index b5138ed5290..490a5ec3fac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6716.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6716.json
@@ -1 +1 @@
-{"ACTRAPID": 7.336652671392606, "FIASP": 30.916721805438318, "IBUPROFEN": 1.0904163975460104, "LEVEMIR": 7.794624856468626, "NOVORAPID": 2060.6516560101154, "SAXENDA": 1.7091002108728253, "SIMPONI": 4.412322200448869, "STELARA": 3.318890499698033, "TREMFYA": 74.06748461655228, "TRESIBA": 28.020593773302192}
\ No newline at end of file
+{"ABATACEPT": 12.69075821063018, "ADALIMUMAB": 7.353894197048209, "ANAKINRA": 69.45912463486013, "ARIPIPRAZOLE": 8.316406116964382, "CICLOSPORIN": 5.802453530347779, "CIMZIA": 11.80636611549604, "COMIRNATY": 0.188849607383665, "COSENTYX": 5.9443647597749045, "ENBREL": 4.088592319942951, "GARDASIL": 9.383357027318214, "HUMIRA": 10.444140340637327, "LEFLUNOMIDE": 17.801224108714596, "MMRVAXPRO": 3.620966937599512, "ROACTEMRA": 13.54589143475627, "SIMPONI": 5.114619455766403, "null": 0.6799430756156122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6717.json
index 1a343e6a1e7..8d247143224 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6717.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6717.json
@@ -1 +1 @@
-{"GARDASIL": 42.803307723476735, "null": 2.19641142827624}
\ No newline at end of file
+{"GARDASIL": 64.7540181829206, "null": 0.6781670157280706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6718.json
index 224a9efd3d1..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6718.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6718.json
@@ -1 +1 @@
-{"STELARA": 7.045932267735833, "null": 3.8676647592770874}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6719.json
index ecb89d16e21..45c14136a01 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6719.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6719.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 6.712555036788778, "EMPAGLIFLOZIN": 67.54661012311233, "ENTRESTO": 11.71672629759177, "INSULIN": 25.6958108516746, "OLANZAPINE": 8.01080142083515, "SITAGLIPTIN": 290.8439585151044, "null": 2.2660193473742134}
\ No newline at end of file
+{"AFINITOR": 49.383574297019024, "AVASTIN": 12.191234908350284, "COSENTYX": 6.99205854160406, "FASLODEX": 11.426985206418728, "KEYTRUDA": 25.462602647392107, "OFEV": 15.814963824351024, "null": 0.7691779134988325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/672.json
index 59db88e4b0b..dd40f9bfdd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/672.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/672.json
@@ -1 +1 @@
-{"null": 1.35440634945964}
\ No newline at end of file
+{"JARDIANCE": 5.178057238962451, "LAMIVUDINE": 32.785953755349425, "LEVOFLOXACIN": 6.325101288809947, "TOZINAMERAN": 0.6230271262684548, "null": 2.166260971022489}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6720.json
index ba234cd1316..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6720.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6720.json
@@ -1 +1 @@
-{"GARDASIL": 7.150586329123432, "HUMALOG": 10.606230974206628, "null": 5.092955636029015}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6721.json
index bf7561d56c0..378419ca529 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6721.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6721.json
@@ -1 +1 @@
-{"APIDRA": 4.190460787440595, "IBUPROFEN": 1.9659068097320536, "LANTUS": 3.2670598897362484, "NOVORAPID": 19.287825546322203, "SAXENDA": 4.758113216793893, "null": 9.43895845494856}
\ No newline at end of file
+{"ABACAVIR": 9.935784191756234, "ATAZANAVIR": 52.27086451743866, "ATRIPLA": 0.3577424976036358, "BASILIXIMAB": 31.38938057871821, "BIKTARVY": 30.559655366828103, "BUSULFAN": 14.87741669131619, "CARMUSTINE": 40.38646349054193, "CELLCEPT": 17.02312135935345, "CICLOSPORIN": 44.664078714298284, "COMBIVIR": 26.95667750797016, "DESCOVY": 47.905623362700105, "EFAVIRENZ": 107.17435288554265, "EMTRICITABINE": 25.14681877757972, "JAKAVI": 7.692420246027545, "KALETRA": 16.649047658593556, "LAMIVUDINE": 22.47138384422397, "METHOTREXATE": 2.534087528698, "MYCOPHENOLATE": 29.32600102404875, "TIVICAY": 36.84762850203537, "TRUVADA": 1.6333543785938271, "null": 0.3168926689935094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6722.json
index c8897261e2f..c2d4afeaa0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6722.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6722.json
@@ -1 +1 @@
-{"GARDASIL": 63.06277500021524, "null": 3.582119543491137}
\ No newline at end of file
+{"ENCORAFENIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6723.json
index 354ce6f9250..fa2a5cec173 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6723.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6723.json
@@ -1 +1 @@
-{"null": 2.3785921265590324}
\ No newline at end of file
+{"XOFIGO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6724.json
index 3de9d29148a..0e7d8a4cb83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6724.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6724.json
@@ -1 +1 @@
-{"BIKTARVY": 21.230167513596108, "null": 10.502921019704605}
\ No newline at end of file
+{"null": 0.6572227330518101}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6725.json
index a2c85ea3a95..4f6fe13e87d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6725.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6725.json
@@ -1 +1 @@
-{"null": 9.487583063695}
\ No newline at end of file
+{"BEXSERO": 93.15436537267972, "COMIRNATY": 0.311022389170072, "INFANRIX": 123.9690523837094, "NIMENRIX": 21.98349545687021, "PREVENAR": 157.09340249396317, "ROTATEQ": 257.7779281044644, "null": 1.532624190159869}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6726.json
index 4c78b6fc058..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6726.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6726.json
@@ -1 +1 @@
-{"BIKTARVY": 40.79061362810873, "IBRANCE": 16.42254706027971, "null": 3.041990472461201}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6727.json
index 92aa40bf227..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6727.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6727.json
@@ -1 +1 @@
-{"COSENTYX": 1.858065564123044, "ELIQUIS": 1.0059024458087351, "EXFORGE": 5.314014646248573, "IBRANCE": 1.8014740738944688, "SIMPONI": 5.042618412150207, "STELARA": 6.782418162370936, "null": 4.237851257421613}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6728.json
index ba33c966389..9ed96e3a06b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6728.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6728.json
@@ -1 +1 @@
-{"BYDUREON": 38.02297957018376, "ELIQUIS": 5.091454360551792, "JANUVIA": 7.323581151586458, "SIMPONI": 5.663599511864924, "STELARA": 4.0151584796472095, "null": 2.9803549550841804}
\ No newline at end of file
+{"SUBOXONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6729.json
index f168b7f886d..9333eb3971e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6729.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6729.json
@@ -1 +1 @@
-{"APIDRA": 7.495901403956943, "NEVANAC": 475.8685099859572, "null": 8.677353264109586}
\ No newline at end of file
+{"null": 1.5316559125282017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/673.json
index cd9662813ba..9612589d244 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/673.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/673.json
@@ -1 +1 @@
-{"ARANESP": 31.458975001674865}
\ No newline at end of file
+{"BENZODIAZEPINES": 190.05902887406697, "COMIRNATY": 0.5472427543057305, "FENTANYL": 8.321763422545263, "KEPPRA": 2.862617832475548, "SPIKEVAX": 0.3157667155108387, "TOZINAMERAN": 0.5196529728160635, "VAXZEVRIA": 0.3518922801405517, "null": 2.112709641414212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6730.json
index 364d03d3c93..4988e52cdd6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6730.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6730.json
@@ -1 +1 @@
-{"ACTRAPID": 7.995969630384268, "APIDRA": 1.5698882336028503, "BRAFTOVI": 6.193438917247973, "COLOBREATHE": 173.9784084673403, "ENTRESTO": 1.406136164279754, "FIASP": 58.579206366307375, "GALAFOLD": 22.632470588815448, "IBUPROFEN": 1.0620047757048554, "JANUMET": 1.5519810466648245, "LEVEMIR": 10.355565363942771, "MICARDIS": 2.749569767991811, "NINLARO": 17.10124564727359, "NOVORAPID": 278.4674230502161, "STELARA": 1.0721211290482022, "TRESIBA": 37.1247308729641, "VELTASSA": 7.1747585753016505, "XTANDI": 2.810342116830472, "null": 2.4561054683055548}
\ No newline at end of file
+{"BEOVU": 1156.887711329971, "BROLUCIZUMAB": 427.41863587669104, "EYLEA": 115.2016761175119, "null": 1.9489848619137644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6731.json
index f888550cab3..00c2d556dd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6731.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6731.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1445485929932293, "LANTUS": 1.2406327880481838, "NOVORAPID": 8.550148413329795, "TOZINAMERAN": 1.761090391997243, "VELTASSA": 22.44627072962048, "null": 2.1414856755277847}
\ No newline at end of file
+{"ABATACEPT": 3.639916825124701, "ADALIMUMAB": 1.2716667415776146, "ARAVA": 2.089065802315085, "BUSULFAN": 5.709317209110184, "CICLOSPORIN": 2.227783774185612, "COMIRNATY": 0.2565065597764424, "CYTARABINE": 4.042691824278513, "EYLEA": 11.271441485141237, "KEYTRUDA": 2.243582701957273, "NEVANAC": 40.83127661989203, "PEGASYS": 1.252001821031045, "ROACTEMRA": 4.898466339706872, "SHINGRIX": 2.304845081029533, "SPIKEVAX": 0.257327102078683, "TAGRISSO": 19.58168248049645, "TOBRAMYCIN": 51.800995212431694, "TOZINAMERAN": 0.2331540578351683, "VAXZEVRIA": 0.116155907628248, "ZOSTAVAX": 4.112603853336434, "null": 1.358106818072958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6732.json
index dbbf7a4cdc2..289b1ceca00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6732.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6732.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 52.12205912713963, "BYDUREON": 2.3377121911350414, "MENVEO": 8.599709621853313, "OPIOIDS": 72.06738655976147, "SHINGRIX": 1.2233086041215724, "SOLIRIS": 1.6166777204907656, "SUBOXONE": 321.30788190891906, "null": 1.3011705926227457}
\ No newline at end of file
+{"null": 1.068453339061557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6733.json
index 4ef0344f43f..245b9c27812 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6733.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6733.json
@@ -1 +1 @@
-{"AERIUS": 3.1329042308590327, "AMIKACIN": 4.222294779045326, "APIDRA": 2.753771634500222, "APIXABAN": 1.8507983326406756, "ARIPIPRAZOLE": 3.5915546525770385, "BOSULIF": 1.9481249631933275, "BRAFTOVI": 4.166942773383198, "BRILIQUE": 1.3696852455900024, "BUPRENORPHINE": 1.033215436342524, "CANAGLIFLOZIN": 30.022121513609054, "CLOPIDOGREL": 1.3757499062550471, "COSENTYX": 5.04855056575651, "DESLORATADINE": 6.887527920789664, "ELIQUIS": 2.323487921278806, "EMPAGLIFLOZIN": 3.152934165131456, "ENTRESTO": 7.364862618951516, "EXFORGE": 4.134033899364286, "FASLODEX": 1.13232402533663, "FENTANYL": 2.1876603930230245, "HUMALOG": 1.711654245862986, "IBRANCE": 2.093625124404104, "IBUPROFEN": 1.7182717731636714, "INLYTA": 1.6713968354041766, "INSULIN": 1.4706724976806258, "ISENTRESS": 1.9652920498101356, "JANUMET": 1.4786273558189549, "JANUVIA": 1.5982085366290537, "KEPPRA": 2.0291223239961407, "LEVETIRACETAM": 1.440110572523038, "LIXIANA": 5.28942153508757, "LONSURF": 2.4059803976167813, "LYNPARZA": 1.5834200093350468, "MELATONIN": 4.53425719078641, "NOVOMIX": 30.03727917918204, "NOXAFIL": 9.248677374246196, "OCALIVA": 15.9354432815253, "OLANZAPINE": 1.383440589741097, "OPTIMARK": 2.0259540127447817, "PREGABALIN": 5.014435051271363, "RAPAMUNE": 10.131909055004488, "REVATIO": 2.268025085308202, "RUBRACA": 1.7671227803634262, "SIMPONI": 1.7142721855018412, "SOMATROPIN": 10.437622371213305, "SPIRONOLACTONE": 2.582734282324931, "STALEVO": 4.978415313901908, "STELARA": 1.7166249563970462, "SUBOXONE": 2.250476900541265, "TOVIAZ": 6.357167940172565, "TRELEGY": 1.474211501943668, "VFEND": 1.9722561080090104, "VIAGRA": 1.2133217793708413, "VICTOZA": 1.0992827303375747, "XELJANZ": 3.9116832129130055, "null": 2.831118956680083}
\ No newline at end of file
+{"LEVOFLOXACIN": 34.71163656045561, "VORICONAZOLE": 197.4420336351838, "null": 0.9044743737771784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6734.json
index 1a2479dd798..3c77995e869 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6734.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6734.json
@@ -1 +1 @@
-{"AERIUS": 15.2101453494379, "ANORO": 6.290351626603902, "APIDRA": 1.9414678479460228, "AVAMYS": 10.770024469938852, "BUPRENORPHINE": 4.788986931744423, "CABOMETYX": 4.451519699639776, "CLOPIDOGREL": 11.744262975471695, "ENOXAPARIN": 5.362835264440401, "ENTRESTO": 1.207660675578471, "EYLEA": 3.486657940211172, "FENTANYL": 1.1735026685213874, "IBRANCE": 2.314142591208772, "INSULIN": 1.9300882569289035, "JANUMET": 5.861640684954498, "JANUVIA": 2.526348914057953, "LANTUS": 2.644677382771607, "OLANZAPINE": 1.3579441484136647, "PLAVIX": 1.3860545476822823, "RELVAR": 15.583271941775324, "TICAGRELOR": 28.85639652403592, "TOUJEO": 4.653400593218763, "TRELEGY": 9.139149993361707, "XARELTO": 5.062092678220416, "XELJANZ": 4.481664173472336, "null": 2.756272689832585}
\ No newline at end of file
+{"NEXAVAR": 24.94634059531697, "VEMURAFENIB": 986.3177331040152, "ZELBORAF": 690.1300972073765, "null": 0.1914678254112203}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6735.json
index 8b47102e7a0..b88c50e90c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6735.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6735.json
@@ -1 +1 @@
-{"null": 8.713709740761487}
\ No newline at end of file
+{"COMIRNATY": 0.3621671211505262, "DEXAMETHASONE": 29.39064660875426, "null": 0.8845734618260478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6736.json
index bb0f10b430d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6736.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6736.json
@@ -1 +1 @@
-{"null": 1.7106632264816388}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6737.json
index b21e2fdf3e7..1d979d302bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6737.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6737.json
@@ -1 +1 @@
-{"ACTRAPID": 10.088048977106665, "ADALIMUMAB": 1.3785998172433995, "AIMOVIG": 1.398726417496266, "APIDRA": 7.321487308441586, "APREMILAST": 10.715493763558364, "BARACLUDE": 2.1234511509134344, "BRIDION": 2.44255953154262, "BRIVIACT": 1.6444932516238022, "BUPRENORPHINE": 2.213004071972424, "BYDUREON": 16.076680641113548, "BYETTA": 4.809079677645833, "CIMZIA": 1.9875619440923105, "COAPROVEL": 1.040417805975099, "DUORESP": 24.653601987947177, "EVENITY": 1.1709289280002255, "EVRA": 2.288637478112077, "FIASP": 29.742685640781005, "INSULATARD": 16.843550912533086, "INSUMAN": 8.006479920118634, "JANUMET": 1.7950057356200309, "KEPPRA": 1.7345644441484571, "LANTUS": 3.993240893555362, "LEVEMIR": 10.178689697245726, "MICARDIS": 2.769245848251092, "MIXTARD": 7.925849101663631, "MMRVAXPRO": 1.5043877747870067, "NEVANAC": 34.439167940621, "NOVORAPID": 43.95207905871248, "NOXAFIL": 2.685614224675173, "OLYSIO": 13.823559289434725, "OMNITROPE": 10.19779197379122, "PEGINTRON": 3.8121735086498303, "PRIVIGEN": 1.0473196298136636, "QUTENZA": 4.776658249530487, "SAXENDA": 5.8477870037826944, "SIFROL": 1.7373260513658442, "SIMPONI": 3.685320170090673, "STALEVO": 2.3635455221260697, "TESTOSTERONE": 13.9082561483666, "TOUJEO": 10.657454019343618, "TREMFYA": 9.74433628234364, "TRESIBA": 21.20750203961347, "VICTOZA": 3.073033449615231, "XOLAIR": 1.041112981478513, "ZONISAMIDE": 7.581383850589211, "null": 3.5561781652399813}
\ No newline at end of file
+{"null": 3.015891500848607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6738.json
index 9b144471db0..0c876bf433d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6738.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6738.json
@@ -1 +1 @@
-{"null": 3.20618593011718}
\ No newline at end of file
+{"BELANTAMAB": 6664.325700344432, "BLENREP": 9172.99842238755, "COMBIVIR": 32.03417284330178, "DEXAMETHASONE": 9.365575606217618, "FLORAJEN": 8587.701475032678, "LEVOFLOXACIN": 15.472801711570453, "null": 1.7038832964140076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6739.json
index d90abb39aee..c6490dabd28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6739.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6739.json
@@ -1 +1 @@
-{"AIMOVIG": 1.4372448137533946, "BRILIQUE": 5.024754561996318, "EXFORGE": 2.287583403744086, "FAMPYRA": 9.363383061255892, "JANUMET": 1.8549332682440824, "JANUVIA": 2.167479693854709, "KEPPRA": 1.4528161952543073, "LEVETIRACETAM": 2.533058174618461, "LIXIANA": 12.95337182245376, "PLAVIX": 1.1165282373052952, "RANOLAZINE": 16.90370673062155, "RINVOQ": 50.648782418079904, "SIFROL": 8.836813178268656, "STALEVO": 10.629254931708047, "TRELEGY": 2.6255185714169857, "UPADACITINIB": 62.28564945344207, "VIRAMUNE": 44.68375910299325, "null": 5.7351314234840665}
\ No newline at end of file
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/674.json
index 3b4af924cc2..fa63b254bae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/674.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/674.json
@@ -1 +1 @@
-{"ELIQUIS": 4.370350849036751, "HUMALOG": 8.959727133086355, "null": 1.1238185029208014}
\ No newline at end of file
+{"null": 0.9302594866885618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6740.json
index ea1dc75c584..d56838552ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6740.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6740.json
@@ -1 +1 @@
-{"INSULIN": 15.763066581367177, "null": 3.7263833547840566}
\ No newline at end of file
+{"null": 0.6781670157280706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6741.json
index ced665c209c..f992da8a660 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6741.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6741.json
@@ -1 +1 @@
-{"null": 4.416696116520047}
\ No newline at end of file
+{"VEMURAFENIB": 695.27951974193, "ZELBORAF": 657.729500189497, "null": 0.1618522454544298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6742.json
index 83bdb7ef55e..345f343827e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6742.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6742.json
@@ -1 +1 @@
-{"IBRANCE": 3.3666547380900558, "JANUMET": 8.240783413111822, "STALEVO": 27.248367343819105, "XTANDI": 157.7860447798756, "null": 1.9550498208796183}
\ No newline at end of file
+{"null": 2.588873808515698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6743.json
index 34f06e7cf47..056e5b4282b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6743.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6743.json
@@ -1 +1 @@
-{"BRILIQUE": 8.046603787996911, "BYDUREON": 19.281671564516795, "VELTASSA": 26.677681737825765, "null": 9.327814922420602}
\ No newline at end of file
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6744.json
index 1ad95a66c47..92e473ab98a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6744.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6744.json
@@ -1 +1 @@
-{"ABASAGLAR": 17.368902802593887, "ACTRAPID": 8.633175288682734, "AIMOVIG": 6.538863636427508, "APIDRA": 22.440878059765357, "ARANESP": 3.653994517612783, "BENLYSTA": 2.0047198637834733, "BIKTARVY": 1.8231454464905532, "BRIDION": 2.182568284615693, "CIMZIA": 1.394573832451358, "COSENTYX": 1.6560992015741507, "DAPTOMYCIN": 25.602519920043846, "EYLEA": 1.0222900013999867, "FIASP": 16.45900668133971, "FORSTEO": 10.576015123161758, "HUMALOG": 14.61816584765003, "HYQVIA": 8.240110990668715, "IBRANCE": 1.2943195915881371, "INSULIN": 7.805098451626654, "INSUMAN": 22.20525235270007, "JEVTANA": 3.4817700319491998, "LANTUS": 32.01127937242492, "LEVEMIR": 11.31339515297005, "MEKINIST": 2.3554100402015554, "MICARDIS": 1.0789808805712873, "MIXTARD": 8.659812233775915, "NEULASTA": 3.2479137331628327, "NEVANAC": 8.147861805313616, "NOVORAPID": 19.74191149168975, "OMNITROPE": 18.184002506667014, "PEGASYS": 1.2194316625976802, "PLEGRIDY": 1.5887299066125793, "ROACTEMRA": 4.377676497346008, "SAXENDA": 2.6071750114245624, "SIMPONI": 10.434149359929174, "STELARA": 8.201716521915186, "TOUJEO": 52.87165737838029, "TREMFYA": 9.955614743636051, "TRESIBA": 9.764039170526528, "TRULICITY": 3.657975720266613, "VICTOZA": 2.303510269134493, "XTANDI": 1.218360925555204}
\ No newline at end of file
+{"ABASAGLAR": 6.167752790524029, "ACTRAPID": 10.444151458625472, "ALPELISIB": 12.542344745093494, "APIDRA": 11.670945466137614, "ASPARAGINASE": 1.352912344614831, "BYETTA": 0.8395868297327422, "CANAGLIFLOZIN": 34.93317325695415, "COMIRNATY": 0.0294702034754238, "DAPAGLIFLOZIN": 10.097327844507474, "DULAGLUTIDE": 19.77850962049849, "EMPAGLIFLOZIN": 63.66953893745229, "FIASP": 5.852942784178761, "FORXIGA": 96.32441320468398, "GLIBENCLAMIDE": 6.751282271018541, "HUMALOG": 13.481458909057322, "INSULIN": 10.824043715660942, "INSUMAN": 14.836894349817989, "INVOKANA": 49.04761660825751, "JANUVIA": 2.084633540938085, "JARDIANCE": 208.13212310760295, "KEYTRUDA": 1.444972976964991, "LANTUS": 9.2000146299674, "LEVEMIR": 6.94826860401811, "NOVORAPID": 8.493242506327617, "OLANZAPINE": 1.964278954140284, "PEGASYS": 0.3017671523268028, "PEGINTRON": 0.5019107126927528, "PIQRAY": 20.65949515863162, "SPIKEVAX": 0.0175958336825166, "SPINRAZA": 1.996293559041054, "TOUJEO": 3.240557177342316, "TRESIBA": 5.479056995635643, "TRULICITY": 3.762546353834728, "VICTOZA": 1.228401872001699, "ZYPREXA": 5.664235703338711, "null": 0.1721136546171303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6745.json
index 74de6f006ac..f92d69f30e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6745.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6745.json
@@ -1 +1 @@
-{"null": 2.807860034721575}
\ No newline at end of file
+{"APIDRA": 9.114095038352255, "DULOXETINE": 14.906106087745398, "EMPAGLIFLOZIN": 32.904785171522995, "FORXIGA": 89.66649393402682, "HUMALOG": 5.066084236450653, "JARDIANCE": 68.25547436856795, "LANTUS": 7.680777469378942, "OLANZAPINE": 4.96030192555201, "ZYPREXA": 6.1369292381943765, "null": 0.4808959534870577}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6746.json
index dee41cbb58b..6dc360dee12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6746.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6746.json
@@ -1 +1 @@
-{"null": 1.5645262835561466}
\ No newline at end of file
+{"APIDRA": 10.536843631695382, "EMPAGLIFLOZIN": 35.91606200639334, "FORXIGA": 65.15371973409829, "HUMALOG": 10.904558937644586, "INSULIN": 7.867831675773611, "JARDIANCE": 77.6865174676479, "LANTUS": 10.196723116313391, "NOVORAPID": 15.505370335122697, "ZYPREXA": 3.2793548960857444, "null": 0.6014474210915096}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6747.json
index fff570aadee..f8a7405e6a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6747.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6747.json
@@ -1 +1 @@
-{"ABASAGLAR": 7.750088083341915, "BUPRENORPHINE": 1.5648550692568914, "CLOPIDOGREL": 3.3441673211103127, "DESLORATADINE": 6.438806872786277, "DUORESP": 100.00162811000044, "EFAVIRENZ": 2.097835031956915, "EFAVIRENZ/EMTRICITABINE/TENOFOVIR": 216.75931459080996, "EMTRICITABINE": 1.998936865865718, "EMTRICITABINE/TENOFOVIR": 79.69252866459298, "FAMPRIDINE": 60.77426743591488, "FIRDAPSE": 7.632033296057564, "HYDROCHLOROTHIAZIDE": 16.203726705119042, "IDACIO": 11.137470791797783, "INHIXA": 45.58339541123116, "IRBESARTAN": 15.6367401964026, "KEPPRA": 2.671227239653394, "LACOSAMIDE": 4.598251383730196, "LEVETIRACETAM": 9.064376919790805, "MICARDIS": 1.3848665992762237, "OLANZAPINE": 2.278071779154693, "SILDENAFIL": 3.434213382524677, "TELMISARTAN": 20.64133703091313, "TEMOZOLOMIDE": 2.75563338050983, "TERIFLUNOMIDE": 14.914393889373814, "ZYLLT": 27.06103239303645, "null": 11.234851344764856}
\ No newline at end of file
+{"CYMBALTA": 27.79040359143432, "null": 0.7591107809894673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6748.json
index 562cf6dfb15..571b0294264 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6748.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6748.json
@@ -1 +1 @@
-{"AIMOVIG": 2.331346588133291, "BENLYSTA": 11.60850001699639, "CHAMPIX": 2.5991970940644884, "COSENTYX": 3.1035205710981297, "HIZENTRA": 6.8775119565018885, "JAKAVI": 9.658523351269674, "KEPPRA": 1.1685261673920362, "NUCALA": 2.46385016218792, "OPSUMIT": 2.055773797170493, "SHINGRIX": 9.317305533237832, "STALEVO": 35.574906451178286, "XOLAIR": 2.5835795722786825, "null": 3.919727222365293}
\ No newline at end of file
+{"ASPARAGINASE": 287.64491534754814, "null": 0.9307174993918504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6749.json
index 2bb034c5c51..c71ae619bd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6749.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6749.json
@@ -1 +1 @@
-{"HUMALOG": 19.2821272710958, "null": 3.936064980832032}
\ No newline at end of file
+{"ATRIPLA": 1.2612665094256217, "TRUVADA": 2.1221588922214827, "null": 1.5237191120286924}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/675.json
index 432a0035cb5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/675.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/675.json
@@ -1 +1 @@
-{"BEOVU": 93.67428826407624, "SUBOXONE": 8.111207336119344, "TASIGNA": 16.57097312249361, "null": 1.334289485233089}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6750.json
index 47c002a1080..8ef59964a52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6750.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6750.json
@@ -1 +1 @@
-{"JANUMET": 2.124366227912344, "RYBELSUS": 7.9344464610669885, "SYCREST": 23.7928495376452, "VELTASSA": 25.202732683878335, "null": 14.107072374285798}
\ No newline at end of file
+{"ATRIPLA": 1.3526270517793266, "BASILIXIMAB": 60.67202096809904, "CELLCEPT": 4.329506834312014, "CICLOSPORIN": 32.43436264642617, "GANCICLOVIR": 28.75917029524525, "MYCOPHENOLATE": 27.65951176374417, "PEMETREXED": 29.308097536992346, "SOLIRIS": 11.360469572455772, "TRUVADA": 3.869070493460961, "null": 1.179262729223091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6751.json
index 7a5383a87ef..02598cb33bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6751.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6751.json
@@ -1 +1 @@
-{"ADALIMUMAB": 12.397406859206022, "HYQVIA": 205.86537416457296, "SIMPONI": 15.615022045150988, "TOZINAMERAN": 2.0407330818695844}
\ No newline at end of file
+{"ABATACEPT": 1.3977600046351812, "ADALIMUMAB": 0.7204457468790915, "AIMOVIG": 0.8011799531730329, "APIDRA": 2.047087640104844, "ARANESP": 1.3380938747596134, "ARAVA": 3.107925539824746, "ATRIPLA": 1.5991595693526408, "AUBAGIO": 3.403758391958024, "AVAMYS": 1.9926889149053624, "AZATHIOPRINE": 1.2638901794173545, "BELIMUMAB": 49.62409140117257, "BENLYSTA": 10.250514397730178, "BYETTA": 1.442982010297177, "CELLCEPT": 1.8053532954629536, "CICLOSPORIN": 0.3259841779212662, "CIMZIA": 2.576065208960662, "COMIRNATY": 0.0954069004424301, "COSENTYX": 2.6690554734777767, "CYMBALTA": 0.2355030886938664, "ELIQUIS": 1.2443426296796554, "ENBREL": 1.2175696210059892, "ENTYVIO": 1.0204265817236151, "ESBRIET": 1.870802525865984, "EXFORGE": 1.4276544258305028, "EXJADE": 1.73616757959162, "FAMPYRA": 2.2008181046620825, "FASLODEX": 0.859507941621481, "FORSTEO": 1.07950070710634, "FORXIGA": 1.0633976994136425, "GARDASIL": 0.3482496826634083, "HIZENTRA": 10.656839168564728, "HUMALOG": 1.6237961840246968, "HUMIRA": 0.8324888968305522, "IBRANCE": 3.700527406941676, "INVOKANA": 6.30676188283176, "JANUMET": 1.0341712859330472, "JARDIANCE": 2.610619486933351, "KALETRA": 5.590532186095822, "KEYTRUDA": 0.261124481468215, "LANTUS": 2.634478307225094, "LEVEMIR": 1.7628841020699788, "MEKINIST": 1.2853603489039491, "METHOTREXATE": 0.8097061992556936, "NUCALA": 10.880218607146556, "OMALIZUMAB": 1.7410406588423073, "OPSUMIT": 1.757206623677674, "PEGASYS": 0.831339902008722, "PEGINTRON": 0.8203497640099507, "PLAVIX": 0.5260545546372398, "PRIVIGEN": 1.9764636738255548, "RINVOQ": 1.1280346026220225, "ROACTEMRA": 1.470504874583766, "RUCONEST": 16.055461176545894, "SAXENDA": 1.2190924270707462, "SIMPONI": 5.879128286527264, "SOLIRIS": 1.434262709659829, "SPIKEVAX": 0.1119270311127784, "SPRYCEL": 1.4161549752266025, "STELARA": 2.3230239902489256, "STRIBILD": 1.245567640251018, "SUBOXONE": 1.6509487643249527, "SUTENT": 1.1066201467259176, "SYNAGIS": 1.8921586320099624, "TOVIAZ": 3.9097138864339738, "TOZINAMERAN": 0.9473769633903364, "TRACLEER": 1.1568083253256436, "TRELEGY": 1.0425989133866085, "TREMFYA": 4.6220453896305065, "TRULICITY": 1.084294269961966, "TRUVADA": 1.1416464371049295, "VAXZEVRIA": 0.1440502794406262, "VICTOZA": 1.8180280166841256, "VOTRIENT": 1.060506169492692, "XELJANZ": 9.23069062273853, "XOLAIR": 1.557163990716539, "XTANDI": 2.464779679548623, "ZOSTAVAX": 0.5010671505913297, "null": 0.7571652008351455}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6752.json
index 6240c45f583..241f9074b88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6752.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6752.json
@@ -1 +1 @@
-{"BIKTARVY": 5.0528863367305, "BRAFTOVI": 10.699173929674076, "COMTAN": 12.876704535639782, "EPCLUSA": 8.17758403890649, "FASLODEX": 1.801910690396812, "HARVONI": 4.306244241493999, "HIZENTRA": 3.3341869728334395, "IBRANCE": 2.382685744245473, "JANUMET": 5.592577244810446, "LANTUS": 1.148279287161478, "LEVEMIR": 5.06773272916548, "LYNPARZA": 6.036027443364017, "MELATONIN": 11.137790585126384, "NEVANAC": 73.38824727994127, "SIMPONI": 1.1732358371547829, "STALEVO": 12.432151262976552, "VENCLYXTO": 49.14598022544505, "VENETOCLAX": 20.586116624249826, "XTANDI": 14.154089949971391, "null": 3.784861482209704}
\ No newline at end of file
+{"IBUPROFEN": 25.19540824670632, "KALETRA": 27.202398331586476, "null": 3.6817379112496873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6753.json
index d0120a74731..9428bfca642 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6753.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6753.json
@@ -1 +1 @@
-{"ABILIFY": 5.033011443581888, "ADALIMUMAB": 1.3954476964107505, "ADCETRIS": 1.34303659187542, "AERIUS": 2.0808299618657764, "AFINITOR": 1.2671340671761775, "AGOMELATINE": 3.321710721425925, "AIMOVIG": 3.0424462463688844, "ALEMTUZUMAB": 4.414279218738303, "ALITRETINOIN": 21.375050404928874, "ALLI": 6.209801356723792, "ALPELISIB": 1.899736234791156, "AMIKACIN": 3.434552160653675, "AMLODIPINE": 3.1539639476941272, "ANAKINRA": 1.7472253772329869, "ANORO": 2.415880711547481, "APREMILAST": 2.838507746192976, "APTIVUS": 2.6650335679573085, "ARIPIPRAZOLE": 3.835707431722695, "ASPARAGINASE": 1.7044510394786818, "ATAZANAVIR": 3.759087506675887, "ATEZOLIZUMAB": 2.371840889895564, "ATOSIBAN": 27.212735058239723, "AVAMYS": 1.368341946684464, "AVELUMAB": 1.2525551815340177, "AXITINIB": 2.499799584092084, "AZACITIDINE": 2.016403298573421, "AZATHIOPRINE": 2.191676028804119, "AZOPT": 1.3713046423043915, "BARICITINIB": 4.790899862496336, "BASILIXIMAB": 4.91507111556063, "BEDAQUILINE": 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3.4149383306111605, "VFEND": 1.50341062875762, "VIAGRA": 2.501008636836417, "VICTOZA": 1.6360036550204875, "VIGABATRIN": 1.3713046423043915, "VORICONAZOLE": 2.3142966159196474, "VORTIOXETINE": 2.926132667439656, "VOTRIENT": 2.9432936615316785, "XALKORI": 4.037267308891923, "XARELTO": 1.0224738156680004, "XEPLION": 2.3756402356931456, "XOLAIR": 1.3136636837717677, "ZONISAMIDE": 5.012743940558878, "null": 2.0168569315924803}
\ No newline at end of file
+{"null": 0.3900087783156435}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6754.json
index 5357f1f5d3c..1f3a4aa6b95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6754.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6754.json
@@ -1 +1 @@
-{"ABACAVIR": 11.108501861523091, "ABATACEPT": 2.535007626375071, "ABILIFY": 1.216189174893289, "ADALIMUMAB": 5.208295880848833, "ADCETRIS": 1.383500448274726, "ADCIRCA": 1.1565310404515805, "ADENURIC": 1.059903284889578, "AERIUS": 3.10136072162112, "ANAKINRA": 1.522772584072696, "APIDRA": 3.203746619264044, "APREMILAST": 2.3079170981950936, "ARAVA": 7.411772078949007, "ARIPIPRAZOLE": 2.954572614324533, "ATEZOLIZUMAB": 1.412433768548024, "AUBAGIO": 1.2615771278804526, "AVELUMAB": 1.2903158218879225, "AZACITIDINE": 1.2677280221428724, "AZATHIOPRINE": 2.049137160534142, "BASILIXIMAB": 1.648529496155165, "BEDAQUILINE": 1.9050347374633996, "BEVACIZUMAB": 1.8506153342900848, "BIKTARVY": 1.1615853415316295, "BORTEZOMIB": 1.2379965241154995, "BOSENTAN": 4.653239195489384, "BRAFTOVI": 1.8976683522177349, "BRIDION": 2.319835937484415, "BRILIQUE": 1.6878990662303195, "BRIVARACETAM": 3.796214371767524, "BRIVIACT": 3.065214551849517, "BUCCOLAM": 10.439739296252949, "BUPIVACAINE": 1.839648265021702, "BUPRENORPHINE": 1.8111003885173376, "BUSULFAN": 1.0652768367421983, "BYDUREON": 1.91797082193171, "CAELYX": 1.9324119279903773, "CARFILZOMIB": 1.852241562744006, "CARMUSTINE": 1.2413109452738722, "CASPOFUNGIN": 1.0120861062332238, "CELECOXIB": 1.400068628634411, "CIDOFOVIR": 7.898429186621002, "CIRCADIN": 3.6287814862931618, "CLADRIBINE": 1.8384974615468856, "CLOFARABINE": 4.355088636534059, "DACLATASVIR": 1.3438288556721096, "DACLIZUMAB": 14.312856635970098, "DARZALEX": 4.576556047949117, "DELAMANID": 5.792457569391681, "DELTYBA": 7.21387344947387, "DESLORATADINE": 2.900080254614198, "DEXAMETHASONE": 1.7369679981626205, "DIFICLIR": 3.005565686521214, "DINUTUXIMAB": 8.80475975568574, "DULOXETINE": 1.0216920093822068, "DUPIXENT": 2.9713349226775883, "ENBREL": 1.2865794612396235, "ENTYVIO": 1.1475492504861504, "ENZALUTAMIDE": 1.0751848857614557, "EPCLUSA": 1.4979634148853485, "ERELZI": 2.939633641442516, "ERENUMAB": 2.1036369800162222, "ESOMEPRAZOLE": 1.0912307623777893, "ETANERCEPT": 1.1218698656510568, "EVRENZO": 13.896638095810998, "FASENRA": 1.299741850305759, "FASLODEX": 1.360004845593147, "FENTANYL": 1.2113624726675942, "FESOTERODINE": 11.161460207839356, "FORXIGA": 1.396524804239094, "FULVESTRANT": 1.1278462760119905, "FYCOMPA": 1.852760848948151, "GANCICLOVIR": 12.993841760372671, "GILTERITINIB": 19.95552235996222, "HEMANGIOL": 19.676594100050394, "HUMIRA": 1.751507120123296, "IBRANCE": 2.2085648386272427, "IMBRUVICA": 1.8674638373933627, "INCRUSE": 1.1285066124860927, "INFLECTRA": 5.035902344249279, "INFLIXIMAB": 5.283887379814758, "INSULIN": 1.7183903217434744, "JANUMET": 1.037084089990248, "KEPPRA": 1.6700048702848571, "KEYTRUDA": 2.923306400686949, "LACOSAMIDE": 2.8886168233752945, "LANTUS": 4.266443632576364, "LEVETIRACETAM": 2.4612933664617938, "LONSURF": 3.912583577097015, "LYNPARZA": 1.9122965825006848, "MACITENTAN": 3.662669903703475, "MELATONIN": 2.4971311887244925, "MELPHALAN": 1.5674687071443492, "MERCAPTOPURINE": 2.1919666233671906, "METFORMIN": 1.012902595969197, "METHOTREXATE": 1.9328053613616472, "MIDAZOLAM": 1.3475487595431663, "NEVANAC": 2.934990284268869, "NOXAFIL": 4.942068034371759, "OLANZAPINE": 1.0258687930253374, "OLAPARIB": 1.4745041390355849, "OPIOIDS": 3.147240815027134, "ORENCIA": 2.784619438870995, "PACLITAXEL": 1.065590339982642, "PADCEV": 17.66970884703083, "PANTOPRAZOLE": 1.6108073538816334, "PEMBROLIZUMAB": 5.152339237576816, "POSACONAZOLE": 2.611424123893368, "PROPRANOLOL": 2.8519503884009936, "QUTENZA": 4.37876656700965, "RAPAMUNE": 3.615909892377676, "RELVAR": 2.666644847523653, "REMICADE": 3.485480502919315, "REVATIO": 9.70986736753094, "RIBAVIRIN": 2.106283945635109, "RIVAROXABAN": 1.2943893684955994, "RUCONEST": 1.412397831730295, "RUFINAMIDE": 25.461701209919077, "RUXOLITINIB": 2.079218485591212, "SAXENDA": 1.5986845818835966, "SILDENAFIL": 2.8464683223840743, "SIMEPREVIR": 14.839077771030553, "SIMPONI": 4.083128065649463, "SIRTURO": 5.170778410045484, "SORAFENIB": 1.9741588455367385, "STELARA": 9.813735862874276, "SUBOXONE": 3.362953270498493, "TELMISARTAN": 3.771594390572568, "TESTOSTERONE": 7.260814834947145, "TIGECYCLINE": 3.2802729536254747, "TOPOTECAN": 4.312006486974255, "TOUJEO": 3.8809653362097616, "TOVIAZ": 1.5472170344954792, "TOZINAMERAN": 1.5874970800035275, "TRAMETINIB": 12.723801347784429, "TRELEGY": 2.0577589425319247, "TREMFYA": 2.857008505851736, "VALSARTAN": 1.2081910180002235, "VFEND": 1.0300691656224634, "VIAGRA": 1.9986966053818576, "VIMPAT": 1.4345716538247173, "VORICONAZOLE": 1.4615834882305507, "XELJANZ": 2.051342810626262}
\ No newline at end of file
+{"ATRIPLA": 7.327401107792125, "null": 1.0033881114169}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6755.json
index aa41fd672e8..628a1a223b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6755.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6755.json
@@ -1 +1 @@
-{"BOTULINUM": 90.84680576452529, "TRELEGY": 24.476145220105938, "null": 1.8319817315764757}
\ No newline at end of file
+{"ADVAGRAF": 45.80172693848392, "ALEMTUZUMAB": 13.953842110620837, "ARANESP": 5.013283674141334, "AZATHIOPRINE": 19.56917118070381, "BASILIXIMAB": 237.7298029655598, "CELLCEPT": 76.27050996325622, "CICLOSPORIN": 73.8416337394747, "IPILIMUMAB": 7.308882660852478, "KEYTRUDA": 1.924308313890116, "MYCOPHENOLATE": 70.929800746366, "RAPAMUNE": 70.48627913963772, "SIMULECT": 453.1409148085539, "SOLIRIS": 14.971613758345857, "TACROLIMUS": 43.66762927488129, "null": 0.5889042437221111}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6756.json
index 849e950b7d4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6756.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6756.json
@@ -1 +1 @@
-{"null": 13.829769084571922}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6757.json
index 3f7a15f3a8c..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6757.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6757.json
@@ -1 +1 @@
-{"ACLIDINIUM": 12.673877489259858, "ADEMPAS": 2.4414356644276016, "AERIUS": 2.161706115810852, "AFINITOR": 2.580564808163351, "ALENDRONATE": 35.30089351652676, "AMBRISENTAN": 10.476618575923926, "AMIKACIN": 1.1639003422452336, "ANORO": 30.20140585661644, "APIXABAN": 7.078654324062947, "ATEZOLIZUMAB": 4.641529942280488, "AVAMYS": 7.774087740959746, "AZATHIOPRINE": 4.019316168300148, "BEDAQUILINE": 2.214394937605768, "BENLYSTA": 3.219902346718569, "BENRALIZUMAB": 8.185417378578126, "BUDESONIDE": 3.0758212251814405, "CANAGLIFLOZIN": 7.393231004927482, "CANCIDAS": 1.1971977208332256, "CICLOSPORIN": 1.17172816506509, "CLOPIDOGREL": 1.0087142824544535, "COSENTYX": 2.0279462924027083, "DARZALEX": 1.065286908297113, "DESLORATADINE": 7.694851592706317, "DOXORUBICIN": 1.4571872078419523, "DUAKLIR": 28.69742741506821, "DULOXETINE": 1.1628004773830192, "DUPIXENT": 4.169174404013628, "ENTRESTO": 1.1701411138573632, "ENVARSUS": 20.920691495028183, "ERELZI": 4.276081027261872, "ESBRIET": 6.254026131592322, "FASENRA": 4.283133141130589, "FILGRASTIM": 2.0603241596788977, "FLUTICASONE": 22.65635746529319, "GLYCOPYRRONIUM": 35.22558742791208, "HIZENTRA": 2.8428069051672966, "IBRANCE": 1.313457248603487, "IBUPROFEN": 1.044907878082967, "INCRUSE": 8.02698776465279, "INFLIXIMAB": 1.2958702984257309, "INLYTA": 1.1724729672280183, "INSULIN": 5.007335850759927, "INVOKANA": 1.7336998747124075, "KAFTRIO": 15.529316403851697, "KALYDECO": 4.167342664848204, "MANNITOL": 6.105726415386842, "MEPOLIZUMAB": 20.413055348865477, "METHOTREXATE": 3.4274743557448204, "MYCOPHENOLATE": 1.3326113614013102, "NAGLAZYME": 5.686594710825485, "NUCALA": 20.470575809479367, "OFEV": 7.921496209644519, "OMALIZUMAB": 14.520690253880655, "OPSUMIT": 3.196057559369708, "ORKAMBI": 6.474440952637258, "PANTOPRAZOLE": 4.8275802264505145, "PEGASYS": 1.2829420693175693, "PREGABALIN": 2.982245868860357, "RELVAR": 11.25046981692471, "REVATIO": 1.6648104951483644, "RITUXIMAB": 2.3197037309607724, "RIVAROXABAN": 3.8019640934753776, "SILDENAFIL": 1.1653423411747064, "SPIRONOLACTONE": 1.1859820809519346, "SYNAGIS": 1.4824413796954268, "TOBRAMYCIN": 2.4334306499190306, "TRACLEER": 1.2653858008627206, "TRELEGY": 12.065951279697362, "UMECLIDINIUM": 18.87535857273193, "VALSARTAN": 1.5939195497592225, "VARENICLINE": 14.740983499543688, "XELJANZ": 1.7047456323647316, "XOLAIR": 7.555071575066395}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6758.json
index 9a05ddb4c06..1c6822b9780 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6758.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6758.json
@@ -1 +1 @@
-{"null": 2.242505380349595}
\ No newline at end of file
+{"ALEMTUZUMAB": 46.69215331032196, "CARMUSTINE": 173.3695267637119, "CICLOSPORIN": 6.337852582641347, "DEXAMETHASONE": 9.43008390313144, "GANCICLOVIR": 56.73331181658339, "PEGASYS": 3.1353055812921675, "RITUXIMAB": 16.86111151313305, "null": 0.4068208406939804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6759.json
index b8933b0ae1e..21f9fc12102 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6759.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6759.json
@@ -1 +1 @@
-{"null": 4.194235525893107}
\ No newline at end of file
+{"ALEMTUZUMAB": 7.998029486975804, "AMIKACIN": 95.87163851363572, "ANIDULAFUNGIN": 74.67587544324111, "ASPARAGINASE": 7.15072821700264, "BASILIXIMAB": 28.51725129953702, "BORTEZOMIB": 33.79957877498846, "BUSULFAN": 36.04715760486412, "CELLCEPT": 3.812236155996005, "CICLOSPORIN": 10.255884483844374, "COLISTIMETHATE": 171.0713704104597, "COMIRNATY": 0.0466700797807896, "CYTARABINE": 13.35309864921058, "DEXAMETHASONE": 10.959933776846317, "JARDIANCE": 2.843553595414779, "KEPPRA": 1.4344148145773776, "LEVOFLOXACIN": 3.3609085330345536, "METHOTREXATE": 2.608754135930819, "MYCOPHENOLATE": 33.60958885421392, "RITUXIMAB": 5.658079866612463, "SOLIRIS": 7.061934218380748, "TIGECYCLINE": 172.88050144707557, "null": 0.5919552280964367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/676.json
index f81c3e560b4..4aaa098c249 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/676.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/676.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1326896390931698}
\ No newline at end of file
+{"null": 1.1886398168110262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6760.json
index 1cf993b6da5..5196dd68476 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6760.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6760.json
@@ -1 +1 @@
-{"null": 3.79363972685902}
\ No newline at end of file
+{"ALEMTUZUMAB": 17.30757656467466, "ASPARAGINASE": 42.801394379308704, "BUSULFAN": 17.170740857471497, "CELLCEPT": 12.69374132689124, "CLOFARABINE": 136.05771328017923, "CYTARABINE": 22.266361062781044, "DEXAMETHASONE": 11.035078017806176, "RITUXIMAB": 14.625922889196596, "null": 0.5656604214667129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6761.json
index 80a2af0b022..a185b6ea4eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6761.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6761.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 24.912736912382098, "null": 4.636634725002985}
\ No newline at end of file
+{"PANTOPRAZOLE": 112.564806979257, "null": 0.4744149287199816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6762.json
index b70ce22d08a..3982c4303f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6762.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6762.json
@@ -1 +1 @@
-{"ABACAVIR": 1506.060606607389, "CRIXIVAN": 317.3889860292967}
\ No newline at end of file
+{"null": 0.6842411932383017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6763.json
index 26c300515e9..27758240a93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6763.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6763.json
@@ -1 +1 @@
-{"ABACAVIR": 4.986634574696754, "ALEMTUZUMAB": 58.48425720886843, "ATAZANAVIR": 11.761033010294092, "AZACITIDINE": 16.383356634562368, "AZATHIOPRINE": 3.8713836987885566, "BENLYSTA": 8.222367582116624, "BIKTARVY": 4.782743068794248, "BORTEZOMIB": 33.05804275521204, "BUSULFAN": 16.87596785205346, "CAELYX": 11.182075505572945, "CARFILZOMIB": 77.86589480704242, "CARMUSTINE": 35.32857658513915, "CELLCEPT": 32.34308123787983, "CICLOSPORIN": 4.265587372359194, "CIDOFOVIR": 88.93765803221706, "CYTARABINE": 5.10487787093283, "DEXAMETHASONE": 6.673065806855803, "DOLUTEGRAVIR": 31.865709654787818, "DOXORUBICIN": 12.903090360990753, "EFAVIRENZ": 14.39666948916742, "ENTYVIO": 4.6548154297163205, "EPIVIR": 17.022703380064378, "FAMPYRA": 6.029842328011755, "FILGRASTIM": 15.817642690554772, "GAZYVARO": 61.29121853312946, "IBRUTINIB": 38.77745130906629, "INDINAVIR": 79.22306257314399, "JAKAVI": 4.5239408838045065, "KALETRA": 11.558470089264862, "LAMIVUDINE": 14.334710120202152, "LEMTRADA": 6.967018618871005, "MABCAMPATH": 67.38752508970668, "MABTHERA": 89.70245689681086, "METHOTREXATE": 3.486667897006588, "MYCOPHENOLATE": 7.6479679881112705, "OBINUTUZUMAB": 24.636375546315737, "RITUXIMAB": 19.67093241726139, "TIVICAY": 20.686411956313982, "TYSABRI": 116.42808810046051}
\ No newline at end of file
+{"null": 0.7618228783228234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6764.json
index 4c456ab45ee..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6764.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6764.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 62.88352257039343, "AUBAGIO": 96.75645972030392, "FAMPYRA": 152.731634913918}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6765.json
index 5443dcc7ce4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6765.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6765.json
@@ -1 +1 @@
-{"OLANZAPINE": 41.07468947631209}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6766.json
index b63c4aa5387..82de2acbc32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6766.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6766.json
@@ -1 +1 @@
-{"null": 4.979405671064821}
\ No newline at end of file
+{"ABATACEPT": 9.608013754360067, "ADALIMUMAB": 5.035535320651137, "ANAKINRA": 27.36559279929388, "APREMILAST": 18.174431140073462, "ARAVA": 18.665674773479456, "ATRIPLA": 1.2365507478688278, "AUBAGIO": 0.9287581329343128, "BENLYSTA": 3.369721812508712, "BYETTA": 1.849397368703295, "CIMZIA": 4.01810637009588, "COSENTYX": 1.0178787740412083, "CYMBALTA": 0.5375074255902803, "ELIQUIS": 0.970461569213164, "ENBREL": 9.160917505316515, "EVISTA": 3.083171556162263, "FENTANYL": 0.4062326027873931, "FORSTEO": 1.9036383389410487, "HIZENTRA": 1.9379239391477847, "HUMALOG": 1.2191630284667772, "HUMIRA": 5.774773548136743, "HYDROCORTISONE": 4.4038466671475165, "IBRANCE": 1.2761301614219496, "INSULIN": 0.6682037600099219, "JANUMET": 1.0175580424601782, "JANUVIA": 2.722173967592781, "JARDIANCE": 1.5950257000821857, "KALETRA": 0.9776887959352916, "LANTUS": 3.1919786356234447, "LEVEMIR": 1.5788093631257012, "LYRICA": 0.7040375199536162, "METHOTREXATE": 0.4736355622115984, "NOVOSEVEN": 4.52778934410037, "NUCALA": 0.6273774366305658, "OMALIZUMAB": 1.1390572759266095, "OPSUMIT": 1.7922359233191152, "RINVOQ": 2.3615956868147365, "SAXENDA": 1.4051088704398815, "SIMPONI": 11.67109699116381, "STELARA": 2.614509804029364, "STRIBILD": 0.5392623422468477, "TOZINAMERAN": 0.0472757978703293, "TRACLEER": 1.2339863016289223, "TRELEGY": 2.0565848986842274, "TREMFYA": 6.178566478356277, "TRUVADA": 0.7116806760748068, "VICTOZA": 2.091269222626312, "XELJANZ": 5.01771565688022, "ZOSTAVAX": 8.676363338018346, "null": 0.5948286069087295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6767.json
index 14a1c97326e..8b681718f88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6767.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6767.json
@@ -1 +1 @@
-{"INSULIN": 289.7063554763469, "MEPOLIZUMAB": 64.75583166018866, "NUCALA": 34.643651327455025, "TELMISARTAN": 84.50497864567333}
\ No newline at end of file
+{"ENBREL": 6.471926786740402, "SUBOXONE": 7.416324534699641, "XELJANZ": 5.358328606677833, "null": 3.023229988193342}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6768.json
index 0cc3689bf28..5db3246a8bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6768.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6768.json
@@ -1 +1 @@
-{"null": 1.95785984818979}
\ No newline at end of file
+{"ATRIPLA": 0.5801541105425597, "AUBAGIO": 1.8316321109970015, "BENLYSTA": 2.768289005750882, "CIMZIA": 4.766740774216468, "ELIQUIS": 1.7601619546634195, "FORSTEO": 1.914807724137846, "HIZENTRA": 5.82315326293442, "HUMIRA": 4.597912762525225, "IBRANCE": 3.090493648508134, "JANUMET": 6.229092988363275, "JANUVIA": 5.599579872559818, "JARDIANCE": 3.5196769297492443, "LANTUS": 5.001069522119328, "LEVEMIR": 5.214180726339435, "NAGLAZYME": 9.440127909780838, "OPSUMIT": 1.8666166259092016, "RINVOQ": 13.674257204505924, "SIMPONI": 18.917000821009115, "STELARA": 4.752709851082453, "TRELEGY": 6.9728565203318364, "TREMFYA": 5.67977403312819, "XELJANZ": 11.374686550174312, "ZOSTAVAX": 6.680453669602684, "null": 1.260382143369297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6769.json
index f40ca8a23b0..1c90b48b0a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6769.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6769.json
@@ -1 +1 @@
-{"null": 2.2796882444559303}
\ No newline at end of file
+{"null": 0.5300222037649106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/677.json
index 0ab044d9660..8ba33825512 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/677.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/677.json
@@ -1 +1 @@
-{"ABATACEPT": 1.774120078994558, "ACCOFIL": 1.1140641419599933, "ACETAMINOPHEN": 1.543898178348843, "ACLASTA": 1.4263823070646366, "ADALIMUMAB": 1.3947531206314825, "ALDARA": 1.0973368582439922, "ANAKINRA": 1.785510696529542, "APREPITANT": 1.940709269161168, "ARAVA": 1.3808632760826367, "BELIMUMAB": 1.1075679069888864, "BENLYSTA": 1.1858799685074206, "BONVIVA": 2.0490172957917334, "BRODALUMAB": 1.779302395175968, "CHLORHEXIDINE": 2.1918877661036844, "CIMZIA": 1.4338650677906737, "COMIRNATY": 2.3975398424383667, "COSENTYX": 1.4753654410492174, "COVID19": 3.656683919396985, "DENOSUMAB": 1.328789379129466, "ELOCTA": 1.2550981167222863, "ENBREL": 1.7978033219707803, "ENTYVIO": 1.5254135491358451, "ERELZI": 1.3032869660106965, "ETANERCEPT": 1.7188730325986183, "FASENRA": 1.0767698420375718, "FLUCELVAX": 1.77375512699601, "FORSTEO": 1.2798753191240386, "GARDASIL": 1.0528124913862231, "GOLIMUMAB": 1.209384104097463, "GUSELKUMAB": 1.8328798451050008, "HEMLIBRA": 1.2986698907763734, "HEPSERA": 1.2155242006701568, "HUMIRA": 1.4821781892341848, "HYRIMOZ": 1.611876956671632, "IDACIO": 1.556147039746276, "KEVZARA": 1.2548420523841135, "KOVALTRY": 1.1218756463380744, "LEFLUNOMIDE": 1.64198591550963, "LEUPRORELIN": 1.3169947589413842, "MAYZENT": 1.4806691342291751, "METHOTREXATE": 1.0769941108857437, "MOVYMIA": 1.7044914772221025, "NILEMDO": 2.6465026260726554, "OLUMIANT": 1.3136154640438222, "OMNITROPE": 1.2143702147836424, "OPTIMARK": 2.0657666519954696, "ORENCIA": 1.1655096211891205, "PRALUENT": 1.4911494192500028, "REBLOZYL": 1.1908786056061296, "REPATHA": 1.505546564941504, "RISANKIZUMAB": 1.6180001564998738, "SCEMBLIX": 1.782025522360298, "SHINGRIX": 1.036169149225879, "SIMPONI": 1.0047728873418136, "SPIKEVAX": 2.440285985882721, "STELARA": 1.0202443298902062, "TERROSA": 1.7647205171785405, "TOZINAMERAN": 1.4730844189519356, "TREMFYA": 1.3683508839316578, "TWINRIX": 1.1799056254958944, "USTEKINUMAB": 1.027910209834752, "VAXZEVRIA": 2.197046869192503, "VEDOLIZUMAB": 1.624164564400033, "VEMURAFENIB": 2.4287868704359425, "XELJANZ": 1.2625271310415698, "XOLAIR": 1.0621259518642556, "ZARZIO": 1.4518070958873517, "ZELBORAF": 2.534101627650563, "ZIAGEN": 1.1887520547831485, "ZYCLARA": 1.1686332631840046}
\ No newline at end of file
+{"ADALIMUMAB": 86.29767563539538, "ANAKINRA": 113.78756154357916, "null": 0.1546444249720887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6770.json
index cded9665ea6..52f1901f684 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6770.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6770.json
@@ -1 +1 @@
-{"null": 9.9526502563786}
\ No newline at end of file
+{"DABRAFENIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6771.json
index 81c9eb58857..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6771.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6771.json
@@ -1 +1 @@
-{"COVID19": 13.78494150559252}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6772.json
index b7d5b02088f..d2860b18d17 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6772.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6772.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 10.389235100926498, "FENTANYL": 4.302918743034548, "LEVETIRACETAM": 12.247010364483812, "MIDAZOLAM": 15.999732858016284, "null": 12.986844603768988}
\ No newline at end of file
+{"BRIDION": 197.36269659019072, "CLOPIDOGREL": 3.842173225338009, "IBUPROFEN": 11.838898999097168, "LEVOFLOXACIN": 5.745126986812363, "MIDAZOLAM": 16.56736734464267, "null": 3.899557406346749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6773.json
index 936e2618471..eed3a767b16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6773.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6773.json
@@ -1 +1 @@
-{"null": 4.143453142560489}
\ No newline at end of file
+{"CELLCEPT": 37.60511458499304, "JARDIANCE": 18.060760125618323, "null": 1.515392007861441}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6774.json
index d0af0bbe387..9889eeacaaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6774.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6774.json
@@ -1 +1 @@
-{"null": 1.0956447489458954}
\ No newline at end of file
+{"ENBREL": 84.51759346296382, "null": 0.93936999068891}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6775.json
index 6793c943b0d..39ec1586b56 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6775.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6775.json
@@ -1 +1 @@
-{"APROVEL": 1.6966635520483366, "BYDUREON": 3.679508494307686, "BYETTA": 1.1239912466442772, "CABAZITAXEL": 27.93142400814743, "CIALIS": 14.872241062500802, "COSENTYX": 1.842665663984652, "DENOSUMAB": 7.172807603969819, "DOCETAXEL": 3.896826834079503, "ELIQUIS": 1.6603463219124817, "ENTYVIO": 1.4160208043184743, "ENZALUTAMIDE": 22.22920148214569, "ERLEADA": 30.266294219724717, "EXFORGE": 1.685060511964193, "HUMALOG": 1.5356488112047406, "IRBESARTAN": 1.3446774324817516, "JANUMET": 1.1018619588087646, "JANUVIA": 1.1403718410250665, "JEVTANA": 8.027783234947151, "LANTUS": 1.5962379944555165, "LEUPRORELIN": 46.12833308098613, "LYNPARZA": 1.4365355471795234, "METFORMIN": 10.83510027665936, "METHOTREXATE": 2.986319699099029, "MICARDIS": 1.2045868924720822, "NPLATE": 1.9175765243335487, "NUBEQA": 43.88348774865375, "NUCALA": 1.6967559999150308, "OFEV": 1.0268905312088872, "PLUVICTO": 33.937123438531856, "REVLIMID": 1.894458758814404, "ROACTEMRA": 1.1434821391478789, "SILODOSIN": 37.36992534930331, "SIMPONI": 2.0653169739433515, "SKYRIZI": 4.411043624079024, "STELARA": 6.871659265801518, "TESTOSTERONE": 6.712579923483899, "TOVIAZ": 1.7009886836125767, "TRELEGY": 2.602796143928521, "TREMFYA": 5.868992708556217, "VIAGRA": 31.883337595859853, "VICTOZA": 1.0878050505745376, "XELJANZ": 1.2615446567754938, "XOFIGO": 41.50683373793359, "XOLAIR": 1.8496606079045843, "XTANDI": 10.816870647420302, "ZOSTAVAX": 1.6222630692561724, "ZYTIGA": 19.69964984498989, "null": 3.162337002861423}
\ No newline at end of file
+{"AVANDAMET": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6776.json
index aad867051d7..ece600f0f04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6776.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6776.json
@@ -1 +1 @@
-{"ABIRATERONE": 758.3802573695656, "APALUTAMIDE": 383.29016688632737, "CABAZITAXEL": 939.8044844651956, "DEXAMETHASONE": 3.499165893191574, "DOCETAXEL": 32.343223176880564, "ELIQUIS": 1.19338450533996, "ENZALUTAMIDE": 102.2266905141083, "ERLEADA": 211.62250043889804, "JEVTANA": 20.39173520269268, "PLUVICTO": 206.69547058818415, "STELARA": 2.4072680104884103, "XOFIGO": 274.5854082570385, "XTANDI": 23.287040880013382}
\ No newline at end of file
+{"APIXABAN": 5.762921965899396, "ATRIPLA": 1.92751475400236, "BUPIVACAINE": 93.79916046123002, "EVISTA": 30.83734398551614, "MEPOLIZUMAB": 11.499779349853936, "NAGLAZYME": 47.95198316963607, "SPINRAZA": 19.4294991677899, "ZOSTAVAX": 4.545028997244483, "null": 1.4770282628606313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6777.json
index b021927da15..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6777.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6777.json
@@ -1 +1 @@
-{"VIAGRA": 21.43258406191056, "XTANDI": 16.770769596990146}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6778.json
index 62c2fe3564e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6778.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6778.json
@@ -1 +1 @@
-{"null": 2.9407983789400665}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6779.json
index d0e9fae7269..9d8b998363a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6779.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6779.json
@@ -1 +1 @@
-{"null": 7.229322137377884}
\ No newline at end of file
+{"LEVODOPA": 1272.462204249185, "null": 0.8215158129056229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/678.json
index 59efecf4886..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/678.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/678.json
@@ -1 +1 @@
-{"ABATACEPT": 5.744678399975245, "ACLASTA": 8.015668489391434, "ADALIMUMAB": 4.966033072458957, "ALISKIREN": 14.833735459789397, "AMINOSALICYLIC": 2.52395774711242, "ANAKINRA": 2.9993302429471487, "ARAVA": 2.601940896681242, "AVAMYS": 2.370351010010433, "AVELUMAB": 4.3810188036593765, "AZATHIOPRINE": 2.199008872674337, "BARICITINIB": 65.7265361981178, "BELIMUMAB": 11.67689489268312, "BENLYSTA": 2.818988549588164, "BONVIVA": 1.229164500630474, "BRAFTOVI": 1.0184516012158609, "BYDUREON": 1.5153519634895218, "BYETTA": 2.191877763533141, "CANNABIDIOL": 3.9038755677663466, "CELECOXIB": 3.4023720723841264, "CIALIS": 1.2347332930941584, "CICLOSPORIN": 1.1038394705205627, "CIMZIA": 2.0671371760664337, "CLOPIDOGREL": 1.0953828212108732, "COSENTYX": 5.940349574184624, "DARUNAVIR": 1.697822028972243, "DASATINIB": 1.3922247815090136, "DUPIXENT": 1.490330130310469, "ELIQUIS": 1.0000165699468735, "EMPAGLIFLOZIN": 1.3569397456679897, "ENBREL": 3.985767813405747, "ENTYVIO": 2.1650567359660524, "ERELZI": 5.078939762959454, "ESOMEPRAZOLE": 2.184613741701468, "ETANERCEPT": 2.194497127806509, "EVISTA": 1.8163527063251088, "FASENRA": 1.070768604363233, "FASLODEX": 1.6365455180640285, "FLUTICASONE": 2.4227745147164628, "GLYCOPYRRONIUM": 3.065367556652224, "GOLIMUMAB": 6.00074716211868, "HUMALOG": 3.2927484422081994, "HUMIRA": 5.672546780484407, "IBRANCE": 1.4527199082421012, "IDACIO": 12.91222712264465, "ILARIS": 3.642187158944324, "INFLECTRA": 3.0635623332367925, "INFLIXIMAB": 1.4195369010977772, "IPILIMUMAB": 5.236890875852426, "JANUMET": 1.818591454086873, "JANUVIA": 1.5903398294811029, "KEYTRUDA": 1.5429562110001636, "LANTUS": 1.3941616477755692, "LEFLUNOMIDE": 5.498450337347067, "LEVEMIR": 1.323826155472004, "LYRICA": 1.317247384776567, "MEPOLIZUMAB": 1.531824996528265, "METHOTREXATE": 3.6538095580888497, "OMALIZUMAB": 1.3268859463152842, "OPDIVO": 1.6585852928383196, "ORENCIA": 3.443238462424279, "OXYBUTYNIN": 1.6720183725286712, "PEMBROLIZUMAB": 1.768219679004054, "PROLIA": 3.1474188356173176, "REMICADE": 1.315070016468019, "REVATIO": 1.1364568774721473, "RINVOQ": 3.250936412412874, "RITUXIMAB": 1.6522724313861872, "ROACTEMRA": 4.570244922257798, "SIMPONI": 5.314071309640637, "SKYRIZI": 2.6599646368819707, "STELARA": 3.6405362883350216, "TOCILIZUMAB": 4.689665923864119, "TOVIAZ": 1.4621524311973704, "TOZINAMERAN": 1.1884781398627522, "TREMFYA": 3.662403435132727, "TWINRIX": 1.6449567751950855, "USTEKINUMAB": 5.884095841308956, "VEDOLIZUMAB": 4.097538891715336, "VIAGRA": 1.2139265931098584, "XELJANZ": 4.122558377241598, "XOLAIR": 1.3863581255101256, "XYREM": 2.431628755455323, "ZOMETA": 2.0453810811446984, "ZOSTAVAX": 4.156397842258508}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6780.json
index a41289f557c..0579db7e98e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6780.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6780.json
@@ -1 +1 @@
-{"null": 6.406470326786169}
\ No newline at end of file
+{"CLOPIDOGREL": 9.28223912587372, "TRELEGY": 12.204449007643952, "null": 5.227320909300265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6781.json
index 0ab25e2fb7e..59c964c8630 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6781.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6781.json
@@ -1 +1 @@
-{"XOFIGO": 669.6419292504548, "null": 1.341242089611436}
\ No newline at end of file
+{"CLOPIDOGREL": 158.1114865001045, "DAPAGLIFLOZIN": 24.689699869269067, "ENOXAPARIN": 27.193413563465764, "OLANZAPINE": 6.417355343399906, "PLAVIX": 12.719068917991832, "TICAGRELOR": 220.60996919041324, "ZOSTAVAX": 17.811299465538177, "null": 0.5550023897024372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6782.json
index d4ccf3c855d..84cd166027a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6782.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6782.json
@@ -1 +1 @@
-{"null": 1.5866082288418275}
\ No newline at end of file
+{"ANORO": 3.282906298825487, "APIXABAN": 2.8991222922430038, "ATAZANAVIR": 2.974460570869642, "BIVALIRUDIN": 34.98619302559191, "BRILIQUE": 1.0975248786946064, "BUPIVACAINE": 6.59517597844562, "BUPRENORPHINE": 0.7080093443761748, "CAPECITABINE": 1.725481791504649, "CICLOSPORIN": 0.5244412711969968, "CIRCADIN": 14.852121223881658, "CLOPIDOGREL": 156.93384994489583, "EDOXABAN": 21.48113485282493, "EFAVIRENZ": 4.895999838538571, "EFIENT": 16.698201360135137, "ELIQUIS": 2.9995788737844102, "ELLAONE": 5.507525391582116, "ENOXAPARIN": 16.8840701608992, "ENTRESTO": 0.5960027323035876, "ENVARSUS": 48.53508073081731, "ESMYA": 17.051385948802324, "FENTANYL": 0.5224676466063225, "IBUPROFEN": 1.5635049280858284, "INCRUSE": 12.478805454018644, "INSULIN": 0.4950492577550739, "KALETRA": 1.4423368626224893, "KEPPRA": 0.2158675892076596, "LIXIANA": 2.7724472863580587, "PLAVIX": 21.64832636522843, "PRASUGREL": 92.53361777587648, "PREGABALIN": 0.9513804013746516, "RANEXA": 4.589921357920211, "RIVAROXABAN": 10.318956831505435, "SPRYCEL": 0.8426955235449242, "TACROLIMUS": 8.395399340523921, "TICAGRELOR": 199.4374895009144, "TRELEGY": 5.713092356640655, "VFEND": 0.6368690389516218, "XARELTO": 11.869543284749875, "ZOSTAVAX": 0.5727643681590929, "null": 0.8243298369740195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6783.json
index f57bacf48d5..e8810aaf282 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6783.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6783.json
@@ -1 +1 @@
-{"null": 2.3324848978728823}
\ No newline at end of file
+{"null": 3.997650473907311}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6784.json
index c4114d5aba4..526861a8218 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6784.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6784.json
@@ -1 +1 @@
-{"JARDIANCE": 47.39973294230192}
\ No newline at end of file
+{"OLANZAPINE": 32.277069382042534, "null": 2.0035678470432274}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6785.json
index 61ddbdbf5aa..27758240a93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6785.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6785.json
@@ -1 +1 @@
-{"null": 1.155800322825551}
\ No newline at end of file
+{"null": 0.7618228783228234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6786.json
index d3f61a018a5..a22a005607e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6786.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6786.json
@@ -1 +1 @@
-{"BYETTA": 72.36487152243265}
\ No newline at end of file
+{"ARAVA": 2.1312807945210435, "COMIRNATY": 0.9323886428605956, "CYMBALTA": 1.644516991946727, "OLANZAPINE": 4.7616878521933135, "SPIKEVAX": 0.5168277567931803, "VAXZEVRIA": 0.4907919092175186, "null": 1.2791648495542116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6787.json
index 2972b9a8dca..452d1e9613e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6787.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6787.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 1.3544155378949028, "ELIQUIS": 8.282018900741669, "HUMALOG": 2.230458706492033, "LANTUS": 1.540399021402314, "MEPOLIZUMAB": 5.523539286681516, "PLAVIX": 1.5181674307906716, "SUTENT": 1.4208745401327216, "TOVIAZ": 9.568910677146164, "VIAGRA": 67.30083479918393, "XELJANZ": 1.098043679310694, "ZOSTAVAX": 7.405651000272421, "null": 2.125424387986033}
\ No newline at end of file
+{"AZATHIOPRINE": 49.35956393741153, "CLOPIDOGREL": 11.953052383727965, "COMIRNATY": 1.1559037789768103, "null": 0.5738691864931794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6788.json
index 5cb24a0b0e8..9f0e4a63920 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6788.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6788.json
@@ -1 +1 @@
-{"ELIQUIS": 22.28347239732169}
\ No newline at end of file
+{"SPIKEVAX": 34.842175210949605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6789.json
index 7d3d1269166..20b7bca94ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6789.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6789.json
@@ -1 +1 @@
-{"null": 1.431887213883862}
\ No newline at end of file
+{"ABACAVIR": 1.7555439726992872, "ABATACEPT": 0.4227758461037631, "ADALIMUMAB": 1.173402242465183, "AFINITOR": 1.2162976687218603, "AMINOSALICYLIC": 2.227604997213776, "APIDRA": 1.3074245036236956, "ARANESP": 2.7919957574002288, "ARAVA": 1.582318271600221, "ATRIPLA": 0.2638813105148808, "AUBAGIO": 1.1869828677864676, "BENLYSTA": 4.011493791593085, "BOSULIF": 6.593079267966624, "BUDESONIDE": 0.7860681031891489, "CABOMETYX": 1.9297045534381696, "CLOPIDOGREL": 0.7708850101396582, "COMBIVIR": 3.758538240824844, "COMIRNATY": 0.0877077640963547, "DARZALEX": 3.033870076213724, "DEXAMETHASONE": 1.5064384663785888, "ELIQUIS": 0.3300170980287221, "ENBREL": 2.0097854070366075, "ENTRESTO": 1.1709674135917665, "ENTYVIO": 1.0248883970072864, "EXJADE": 1.6348851397494486, "FASLODEX": 2.0643361529181057, "FORSTEO": 0.5815647728195077, "FULVESTRANT": 3.21276278350428, "GARDASIL": 0.4388521659592936, "HUMALOG": 0.3270199544559086, "HUMIRA": 3.275137726814768, "IBRANCE": 7.736212562969245, "JAKAVI": 2.139168639565919, "JANUMET": 1.4098813517469828, "KEPPRA": 0.6069559018562334, "KEYTRUDA": 1.2093839440251712, "KISQALI": 3.828933922779064, "LANTUS": 0.3087990758668211, "LEMTRADA": 3.6206094072122887, "LUTATHERA": 10.53113452785168, "LYNPARZA": 2.687254500435971, "MEPOLIZUMAB": 5.049106384806118, "MICARDIS": 1.6310337573905784, "NEULASTA": 4.92181843772609, "NINLARO": 11.40718050355891, "NPLATE": 1.9366989571026283, "OCALIVA": 11.790712629326505, "OPSUMIT": 0.6345993720672432, "PEGASYS": 2.6750691600372205, "PEGINTRON": 1.7310964284839965, "PLUVICTO": 34.39272569593107, "REVLIMID": 5.463269966696396, "RINVOQ": 3.848600489876647, "RUBRACA": 14.57198169930636, "SIMPONI": 1.0595670042103107, "SOLIRIS": 13.688188631590554, "SPIKEVAX": 0.1084935915780227, "SPRYCEL": 1.960713482865976, "STELARA": 0.7858059443342842, "STIVARGA": 1.8088363787973172, "SUTENT": 1.8329747753413548, "TOZINAMERAN": 0.2162544711290057, "VAXZEVRIA": 0.0348716818316201, "VENETOCLAX": 7.153499136707326, "VOTRIENT": 1.426761653276463, "XELJANZ": 2.733610181062031, "XOFIGO": 5.107633534309299, "XTANDI": 1.260838133891354, "ZOSTAVAX": 0.509339682602561, "ZYPREXA": 1.1552387774425514, "null": 1.1918927026982251}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/679.json
index 958942651d2..1fa62ca5f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/679.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/679.json
@@ -1 +1 @@
-{"null": 1.4952445862083286}
\ No newline at end of file
+{"EVENITY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6790.json
index 6b0dc545904..4325171f4a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6790.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6790.json
@@ -1 +1 @@
-{"ELIQUIS": 7.162743490236901, "LANTUS": 6.062088515207667, "null": 1.468864080709966}
\ No newline at end of file
+{"null": 2.74816460155056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6791.json
index a29c7c5b9a2..fd095cadd34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6791.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6791.json
@@ -1 +1 @@
-{"null": 2.5669362932198845}
\ No newline at end of file
+{"SPIKEVAX": 12.19525419628571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6792.json
index 3574745b78e..af09adb1db6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6792.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6792.json
@@ -1 +1 @@
-{"ADENURIC": 133.27292678749092, "ENZALUTAMIDE": 192.27628273134397, "XTANDI": 105.7858051350146}
\ No newline at end of file
+{"null": 5.195249144307421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6793.json
index fa904b662b7..8c3eb67258d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6793.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6793.json
@@ -1 +1 @@
-{"null": 1.055977058825828}
\ No newline at end of file
+{"GARDASIL": 66.52434329736816, "null": 2.297448547694354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6794.json
index 862bb861ddf..30e302bde3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6794.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6794.json
@@ -1 +1 @@
-{"APALUTAMIDE": 97.51335005611386, "CABAZITAXEL": 170.76217460249023, "DENOSUMAB": 13.005275668098822, "DEXAMETHASONE": 1.0392691754573211, "DOCETAXEL": 15.151697270019106, "ENZALUTAMIDE": 217.35708087756328, "ERLEADA": 83.62774384057815, "EXFORGE": 1.2611239350264047, "FORXIGA": 1.2929452039148734, "JEVTANA": 73.54458657594722, "LEUPRORELIN": 233.6534224817427, "LYNPARZA": 12.811893746207485, "NUBEQA": 166.0449101665958, "OLAPARIB": 9.581649539149394, "PLUVICTO": 100.62671114972268, "TAXOTERE": 8.12737713949123, "TESTOSTERONE": 10.009669084425653, "VIAGRA": 2.881588671329942, "XGEVA": 76.98881335539022, "XOFIGO": 246.02777608228257, "XTANDI": 236.49024028387117}
\ No newline at end of file
+{"null": 0.5773065971612161}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6795.json
index 2c272ad6eed..fcf976940e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6795.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6795.json
@@ -1 +1 @@
-{"null": 2.041280120024456}
\ No newline at end of file
+{"COMIRNATY": 4.361243534676912, "SPIKEVAX": 1.2303689598235072, "VAXZEVRIA": 0.9531012503287578, "null": 0.5544781668016266}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6796.json
index 69375042381..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6796.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6796.json
@@ -1 +1 @@
-{"COSENTYX": 1.7559203584407987, "ELIQUIS": 1.1799692911890438, "FORXIGA": 38.072872679888285, "JANUMET": 5.078699765440058, "JARDIANCE": 24.711531922659635, "LEVOFLOXACIN": 2.6023625805693267, "PEGASYS": 1.378534929716582, "SIMPONI": 1.968076161883041, "ZOSTAVAX": 2.2365026655656544, "null": 1.1019531045385094}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6797.json
index b1a086bcd9a..53819af7fc4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6797.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6797.json
@@ -1 +1 @@
-{"BYDUREON": 6.004422029193521, "BYETTA": 4.505551160562772, "CLOPIDOGREL": 8.28124846984374, "ELIQUIS": 2.423047796323768, "JANUMET": 19.20455142904344, "JANUVIA": 15.006842997796722, "JARDIANCE": 5.080528071851669, "SUTENT": 2.153371764956921, "TOVIAZ": 10.84742633209079, "VIAGRA": 24.74928990905141, "ZOSTAVAX": 5.84228560798611, "null": 1.201037424385841}
\ No newline at end of file
+{"CHAMPIX": 3.0727936042571256, "COMIRNATY": 0.7384233563833078, "LANTUS": 1.4121450412146752, "MEPOLIZUMAB": 9.8316859047665, "SIMPONI": 3.1542691961882507, "SPIKEVAX": 0.6402111231886656, "TOZINAMERAN": 4.030737373678735, "VAXZEVRIA": 2.124183589809061, "ZOSTAVAX": 3.0508054115686947, "null": 0.945053800457994}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6798.json
index 3fafa191183..c142b5287b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6798.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6798.json
@@ -1 +1 @@
-{"FORSTEO": 59.85738486807363}
\ No newline at end of file
+{"null": 1.395000896118496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6799.json
index 50acfd02c9b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6799.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6799.json
@@ -1 +1 @@
-{"ENOXAPARIN": 299.5312729577975, "null": 2.8262385602565785}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/68.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/68.json
index 383eae86ca2..b228457ee09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/68.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/68.json
@@ -1 +1 @@
-{"null": 4.02283837449332}
\ No newline at end of file
+{"COMIRNATY": 1.2993412406164475, "null": 0.8229062239386857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/680.json
index 34093432375..505d5305451 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/680.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/680.json
@@ -1 +1 @@
-{"ARAVA": 1.7481747954423337, "CASPOFUNGIN": 15.579829609146616, "CELLCEPT": 2.0156356750894986, "CICLOSPORIN": 1.6009074281666882, "CIMZIA": 3.516786611990874, "COSENTYX": 3.392257456594186, "DAPTOMYCIN": 61.70225519680322, "ELIQUIS": 1.2653151495763844, "ENBREL": 3.0387715170336347, "FENTANYL": 2.8722758902854246, "HUMIRA": 6.066129117527454, "METHOTREXATE": 11.7098688324948, "PEGASYS": 2.023159462034352, "PEGINTRON": 2.976347410812122, "RINVOQ": 3.678470300077306, "ROACTEMRA": 52.76979609328048, "SIMPONI": 9.194166207051572, "STELARA": 1.7317027858824168, "XELJANZ": 3.645172554537759, "null": 1.0423046663961413}
\ No newline at end of file
+{"ARAVA": 15.334681157993126, "null": 0.4309090647495694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6800.json
index ce765b1ec06..4bc9a11bc7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6800.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6800.json
@@ -1 +1 @@
-{"null": 1.967405165801844}
\ No newline at end of file
+{"LANTUS": 31.080996656631854, "NOVORAPID": 29.72033282706073, "PLEGRIDY": 49.50365593678025, "null": 0.9841099869569464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6801.json
index 42494249169..37f92659366 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6801.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6801.json
@@ -1 +1 @@
-{"null": 2.7801871827442293}
\ No newline at end of file
+{"HARVONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6802.json
index 02c6c2f0236..dab1838ea24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6802.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6802.json
@@ -1 +1 @@
-{"COMIRNATY": 1.8078123682197187, "SPIKEVAX": 1.3119354389372615}
\ No newline at end of file
+{"SAXENDA": 362.8339976282431, "null": 0.7404684711556045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6803.json
index 752e9059dad..9ac27f812f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6803.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6803.json
@@ -1 +1 @@
-{"null": 1.1773695953319565}
\ No newline at end of file
+{"COMIRNATY": 0.5356550053300104, "TOZINAMERAN": 3.9743374443739783, "null": 1.4955426464894448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6804.json
index 51cbd2490df..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6804.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6804.json
@@ -1 +1 @@
-{"null": 1.861645065438752}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6805.json
index ca335229b34..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6805.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6805.json
@@ -1 +1 @@
-{"NEXAVAR": 369.74579649025935}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6806.json
index 029252f7ec1..90f7549471c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6806.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6806.json
@@ -1 +1 @@
-{"ATRIPLA": 43.5989040572801, "KALETRA": 7.672892858527975, "STRIBILD": 38.08103452661691, "TRUVADA": 68.75035750194012, "VIREAD": 15.633383854024098}
\ No newline at end of file
+{"COMIRNATY": 0.2136338452914169, "SUTENT": 6.918179913949738, "null": 1.3680277241486762}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6807.json
index 52b2fcee262..af3263aba1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6807.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6807.json
@@ -1 +1 @@
-{"AFINITOR": 6.586807731232621, "DEXAMETHASONE": 2.0582087950586083, "ESOMEPRAZOLE": 8.992006964143311, "EXJADE": 14.599246450086667, "HYCAMTIN": 39.56100020244674, "IBRANCE": 1.424074560518766, "KEYTRUDA": 1.36947981747451, "KYMRIAH": 9.225437549353147, "MEKINIST": 6.385838608670719, "PEGINTRON": 1.838399102536998, "SUTENT": 3.1245991730951266, "VFEND": 4.426889385910149, "XALKORI": 9.520158694719164, "null": 1.2679612433428051}
\ No newline at end of file
+{"IDACIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6808.json
index 4753292d051..8d0c929cf4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6808.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6808.json
@@ -1 +1 @@
-{"ATRIPLA": 18.3844909322867, "CAPECITABINE": 13.209624266290229, "ERIBULIN": 183.550213263826, "EXJADE": 5.443680301476359, "SPINRAZA": 13.204125319543, "STRIBILD": 16.158653148413833, "TRUVADA": 22.18963464029907}
\ No newline at end of file
+{"null": 0.7783440919244126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6809.json
index f91ca4740cf..4c622802e4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6809.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6809.json
@@ -1 +1 @@
-{"AVASTIN": 26.45948413838928, "JARDIANCE": 5.081013445716344, "KEYTRUDA": 13.279910423362985, "SUTENT": 1.8976731011209536}
\ No newline at end of file
+{"null": 1.1699170674426764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/681.json
index 9ba32a3610f..961f482b2d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/681.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/681.json
@@ -1 +1 @@
-{"CASPOFUNGIN": 633.1345390859295}
\ No newline at end of file
+{"AIMOVIG": 0.7260957220168334, "ANORO": 1.849330660986208, "APIDRA": 1.499532495309652, "ARAVA": 0.8118305888760634, "ATRIPLA": 20.673204044029315, "AUBAGIO": 1.6851158821584469, "AVANDIA": 1.2173177296147226, "BYDUREON": 1.0613363807747247, "BYETTA": 1.3077000827354577, "CIMZIA": 0.3958773843515865, "COMIRNATY": 0.0158674596912961, "COSENTYX": 0.6509798764228687, "CYMBALTA": 0.973809823401178, "ELIQUIS": 0.8538686455991957, "ENBREL": 0.92251040115375, "EVISTA": 5.459371210073607, "EXFORGE": 1.0211934922599657, "FAMPYRA": 5.19541312017541, "FORSTEO": 2.988355680426995, "HIZENTRA": 1.4399908230102632, "HUMALOG": 3.3332032486259875, "IBRANCE": 1.626971647572623, "IRON": 6.787211368988364, "JARDIANCE": 0.719664349122756, "KALETRA": 1.079146906236403, "LANTUS": 3.02007218868058, "LEFLUNOMIDE": 4.636964475853394, "LEVEMIR": 1.3126539480229749, "LYRICA": 2.264708260048224, "OCRELIZUMAB": 1.692237130720993, "OMALIZUMAB": 1.0491813293466774, "OPSUMIT": 0.5726541372958271, "PEGINTRON": 0.4943612311122421, "PREGABALIN": 1.6049516570602276, "REVATIO": 2.846316494998712, "RINVOQ": 2.010785037473997, "SAXENDA": 1.400001757574803, "SIMPONI": 1.939372789367459, "SPIKEVAX": 0.0320285816379866, "SPINRAZA": 2.7369788983894483, "STELARA": 0.9541204337334412, "STRIBILD": 16.419407186686197, "SUBOXONE": 3.0492857990740463, "TOVIAZ": 1.5702618327011804, "TOZINAMERAN": 0.0661164811759581, "TRACLEER": 0.7468901193564244, "TRELEGY": 1.1973152160159366, "TRULICITY": 0.9827328046654136, "TRUVADA": 15.434480687157956, "VAXZEVRIA": 0.0316170306812106, "VIAGRA": 2.8047186156148074, "VIREAD": 8.570846317041044, "XELJANZ": 3.940309813247728, "XOLAIR": 1.473391556077981, "ZOSTAVAX": 1.1284432362636594, "ZYPREXA": 0.3861233346913601, "null": 0.6268113095237778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6810.json
index 3566cced93b..f6cc4db0a54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6810.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6810.json
@@ -1 +1 @@
-{"AFINITOR": 1.825036980031484, "ATRIPLA": 5.3953293617237055, "AVASTIN": 7.267891011873724, "BENLYSTA": 3.997195001964161, "BEVACIZUMAB": 6.153686575012781, "CABOMETYX": 12.794677353374064, "CELLCEPT": 2.708384754262631, "CICLOSPORIN": 5.859650477086315, "ENTECAVIR": 42.48409458101086, "EXJADE": 4.064352527770911, "HEPSERA": 28.01542513836638, "INLYTA": 8.561011414028785, "KEYTRUDA": 3.671743505746551, "LANTUS": 1.058070557874632, "LEMTRADA": 8.54560810210846, "LENVIMA": 22.02907929843787, "NEXAVAR": 2.79279986788058, "SOLIRIS": 2.159528002687648, "SPINRAZA": 10.162907183565522, "STIVARGA": 13.60207694931976, "STRIBILD": 12.203197917789748, "SUTENT": 3.368216321373712, "TRUVADA": 7.082237197250877, "VOTRIENT": 2.477851817494573}
\ No newline at end of file
+{"SPRYCEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6811.json
index e7344f31881..e16cfa021a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6811.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6811.json
@@ -1 +1 @@
-{"CICLOSPORIN": 8.765183839157324, "SOMATROPIN": 185.394968085309, "null": 1.575744925955175}
\ No newline at end of file
+{"COMIRNATY": 0.2267079992276429, "ZOSTAVAX": 13.157038806318738, "null": 2.0049042733862388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6812.json
index fef8d0523cb..6ae03218fd7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6812.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6812.json
@@ -1 +1 @@
-{"ABACAVIR": 1.4749559325424944, "AFINITOR": 1.6647848814976525, "AFLIBERCEPT": 14.5899979923462, "ALEMTUZUMAB": 1.6553620737313537, "ATAZANAVIR": 2.731940268553985, "ATRIPLA": 5.9216403271562585, "AVASTIN": 14.67991337313445, "AXITINIB": 10.719986954240738, "AZATHIOPRINE": 1.9377379614228891, "BASILIXIMAB": 5.278645075495335, "BAVENCIO": 9.551171466749564, "BENLYSTA": 2.1200644818300947, "BETAFERON": 1.8707144237316888, "BEVACIZUMAB": 15.406635104997276, "BIKTARVY": 1.1184052546047203, "BORTEZOMIB": 1.3729002596103292, "BYDUREON": 1.17554412564578, "CABOMETYX": 26.788767351491767, "CELLCEPT": 4.029639456439384, "CICLOSPORIN": 7.094904369188273, "COMBIVIR": 1.1028444174078205, "CRIXIVAN": 2.752359486201103, "CYRAMZA": 21.88696057678864, "DACLATASVIR": 3.5154205941141465, "DARUNAVIR": 5.618582939795924, "DASATINIB": 2.612603248618689, "EFAVIRENZ": 1.2959874576200885, "EMTRICITABINE": 6.503786909132362, "ENTECAVIR": 6.678567825246477, "EPIVIR": 1.7788240670186852, "EVEROLIMUS": 2.148518889400526, "EXJADE": 5.915398565375088, "FORXIGA": 1.3658661818102362, "GALAFOLD": 10.428904441011738, "GALVUS": 1.4597366255247244, "HARVONI": 1.758370113279903, "HEPSERA": 13.164315772820816, "IBUPROFEN": 1.7590402416408288, "ICLUSIG": 1.023516051091331, "INLYTA": 11.840970594423409, "INSULIN": 1.3540305698946196, "IRINOTECAN": 3.586411327871009, "KALETRA": 2.6129317627185995, "KEYTRUDA": 13.234297614067325, "LAMIVUDINE": 4.448180624175497, "LEMTRADA": 2.271459153916815, "LENVIMA": 62.09274455717696, "LONSURF": 1.123250263870803, "LOPINAVIR": 3.793714298007711, "LUPKYNIS": 45.94678797603984, "METFORMIN": 7.345176640142861, "MICARDIS": 1.1134137235578627, "MIDAZOLAM": 1.2070052645155271, "MYCOPHENOLATE": 5.134486465657435, "NEXAVAR": 4.354487559138087, "NORVIR": 7.953206706559948, "OZEMPIC": 3.9843664915520103, "PAZOPANIB": 9.60978881754176, "PEMBROLIZUMAB": 4.052773951805703, "PEMETREXED": 2.8281726182896776, "RAPAMUNE": 11.568118061452555, "RASILEZ": 9.098022280081588, "REYATAZ": 2.8791696134844176, "RIBAVIRIN": 1.015676576563272, "SOLIRIS": 6.018766268441128, "SPINRAZA": 7.17713036823594, "SPRYCEL": 1.3542265433828244, "STIVARGA": 9.854963822550864, "STRIBILD": 4.7347056716076406, "SUNITINIB": 9.455354143398926, "SUTENT": 2.8028325769048084, "TAMIFLU": 4.573017070850496, "TELMISARTAN": 2.89361043441058, "TENOFOVIR": 24.1606279256998, "TIVICAY": 2.5393731250062097, "TRUVADA": 6.813157290886251, "VIREAD": 13.078849431429168, "VOTRIENT": 6.281423010616346, "ZALTRAP": 34.85095200530019}
\ No newline at end of file
+{"null": 2.412185102749764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6813.json
index f253eed998a..be36de26838 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6813.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6813.json
@@ -1 +1 @@
-{"AMIKACIN": 120.9803622922906}
\ No newline at end of file
+{"AFINITOR": 0.3464691858399047, "AIMOVIG": 0.3554020922118147, "ALIMTA": 3.733165771183845, "AMGEVITA": 80.34816352545491, "AVAMYS": 2.396298694725053, "AVASTIN": 0.7791019210750332, "BEOVU": 4.228847533318706, "BUDESONIDE": 10.115190666666445, "BUPRENORPHINE": 1.0160234121379603, "BYDUREON": 0.5707309932223934, "CAPECITABINE": 2.5855902840513982, "CARBIDOPA": 17.238572466925273, "CHAMPIX": 1.876347925855374, "CICLOSPORIN": 0.4226388866272366, "CIMZIA": 0.1776356555599984, "COMIRNATY": 0.8065823831432231, "COSENTYX": 0.6688432155309825, "CYMBALTA": 0.1123081743226093, "CYTARABINE": 0.4811738542101177, "DEXAMETHASONE": 0.6709221569852251, "DOCETAXEL": 2.3124370944806736, "ELIQUIS": 0.3348415438641097, "ENBREL": 1.2559886482326723, "ENTRESTO": 0.9126151679962144, "ESBRIET": 0.6005044675285862, "EVOLOCUMAB": 77.51671038697926, "EXFORGE": 0.8539171779133544, "EYLEA": 8.311812188743762, "FASLODEX": 2.7616587199885285, "FENTANYL": 0.2671646206715272, "FLUTICASONE": 23.407131235001675, "FORSTEO": 0.3498212959734506, "FULVESTRANT": 1.524903053507884, "GARDASIL": 0.5571091119848487, "HERCEPTIN": 2.6089338111470703, "HUMALOG": 0.5117822217972235, "HUMIRA": 0.953129000071224, "IBRANCE": 3.983507325439702, "IKERVIS": 111.14353348151823, "JARDIANCE": 0.257350019317157, "KAFTRIO": 1.354893935208099, "KEYTRUDA": 0.3801616394513569, "KISQALI": 4.072918278244662, "LANTUS": 0.6699263455629729, "LEVOFLOXACIN": 0.5868886977689624, "LYRICA": 0.4088917984452597, "MEPOLIZUMAB": 1.8258477776828728, "METHOTREXATE": 2.6615521789863257, "MMRVAXPRO": 1.6594665017567114, "NEVANAC": 19.52864943822285, "NUCALA": 10.842513869207842, "OMALIZUMAB": 2.085990108360453, "OPATANOL": 52.36524843309823, "OPSUMIT": 0.5492896781567851, "PANTOPRAZOLE": 1.9993605301212527, "PEGASYS": 0.8128406941023787, "PEMETREXED": 2.560465838973916, "SHINGRIX": 0.8530649302833959, "SPIKEVAX": 0.6344790119653618, "STELARA": 0.2661546441483166, "SUBOXONE": 1.1270158038195084, "SUTENT": 2.3554626539753007, "TAGRISSO": 0.9092912605361128, "TOZINAMERAN": 1.1311160074733588, "TRELEGY": 1.8558797964378968, "VAXZEVRIA": 0.6578757764089715, "VFEND": 0.7790317056291595, "VIAGRA": 1.2495950209547828, "XELJANZ": 0.3403703751773331, "XOLAIR": 2.6458595144824386, "XTANDI": 1.2393837800227503, "ZOSTAVAX": 1.0337225639729797, "null": 1.3234411684137084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6814.json
index 49497a2bc16..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6814.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6814.json
@@ -1 +1 @@
-{"null": 1.906036144418784}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6815.json
index a2cf01bbfda..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6815.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6815.json
@@ -1 +1 @@
-{"null": 1.2960257441560978}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6816.json
index 394398cb691..3a9d0cf08cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6816.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6816.json
@@ -1 +1 @@
-{"COMBIVIR": 8.294196364349702, "ELIQUIS": 1.0405495725882985, "PLAVIX": 2.0910749344927826, "null": 7.052734413838827}
\ No newline at end of file
+{"null": 2.118328606160788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6817.json
index 7719d6e465e..6a18b23e1b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6817.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6817.json
@@ -1 +1 @@
-{"null": 3.765026251591907}
\ No newline at end of file
+{"COMIRNATY": 2.908967194529306, "SPIKEVAX": 1.1836275112030168, "null": 0.8559744887336724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6818.json
index b2e7b6bb632..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6818.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6818.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6819.json
index 7b8812efc8f..92215c72b5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6819.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6819.json
@@ -1 +1 @@
-{"ADENURIC": 250.0058291022553, "null": 2.180809650515524}
\ No newline at end of file
+{"BUPRENORPHINE": 4.04626721859974, "COMIRNATY": 6.4578209524433685, "SPIKEVAX": 1.7612654340255154, "TOZINAMERAN": 1.3414140110267905, "VAXZEVRIA": 0.2734732071427184, "null": 0.5210479494657132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/682.json
index a80566aa8a8..09999499216 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/682.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/682.json
@@ -1 +1 @@
-{"ARAVA": 7.513313708904587, "CIMZIA": 3.437643931863468, "CYMBALTA": 1.1100025687272927, "ELIQUIS": 1.0044662297234397, "ENBREL": 3.891164551228452, "HUMIRA": 6.003757215095779, "ILARIS": 363.0507514653518, "IRON": 22.68599663096103, "METHOTREXATE": 4.325801482980193, "ROACTEMRA": 12.060393585170235, "SIMPONI": 7.442900895142266, "SUBOXONE": 2.492953101578481, "XELJANZ": 14.23639378974735}
\ No newline at end of file
+{"ARAVA": 2.4790265989066387, "CIMZIA": 4.934941025448542, "JANUMET": 17.87016478392363, "null": 0.801549526354019}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6820.json
index d7429d5d9ad..c610402427a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6820.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6820.json
@@ -1 +1 @@
-{"ASPARAGINASE": 2.426664609599449, "AVANDIA": 1.0427861145626705, "BUPRENORPHINE": 1.3345472874071067, "CELLCEPT": 1.0806024375186378, "CLOPIDOGREL": 3.5260905952348103, "CUBICIN": 3.18714423285526, "ELIQUIS": 1.735345661341287, "ENOXAPARIN": 10.550206288224688, "EXJADE": 1.6229769479028036, "GLIBENCLAMIDE": 8.817379841070919, "IBUPROFEN": 1.0673605481444797, "IRINOTECAN": 3.5924468892495334, "KYMRIAH": 7.042070123370153, "LEVOFLOXACIN": 3.934026653098589, "LIXIANA": 10.43832557775457, "MULTAQ": 2.7897714157547737, "NEXAVAR": 1.445658470359604, "OLANZAPINE": 1.050453816586472, "PLAVIX": 3.488216579291176, "REMDESIVIR": 22.83539663124758, "TAMIFLU": 1.957640478629271, "TRACLEER": 2.5481573219932674, "VFEND": 3.4019035480767585, "XARELTO": 12.939366073535084, "XELODA": 8.384464030534312, "null": 4.14709740468815}
\ No newline at end of file
+{"COMIRNATY": 2.691693581672522, "SPIKEVAX": 1.4153306791852116, "null": 0.6424162645682162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6821.json
index a3dd4d3fa9f..0e17e31c35a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6821.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6821.json
@@ -1 +1 @@
-{"null": 4.115152999235356}
\ No newline at end of file
+{"ABACAVIR": 2.256909516030749, "ABILIFY": 0.3545235440567683, "ACTOS": 3.957634221793165, "ACTRAPID": 2.5535677290363106, "ADENURIC": 5.488137201970899, "AGENERASE": 18.69573347936737, "AMIKACIN": 1.4120047732222736, "APIDRA": 1.0349461448940949, "APREMILAST": 1.647288212821821, "APROVEL": 8.857360107106622, "ATAZANAVIR": 1.3935426662044592, "ATRIPLA": 0.0964294232718426, "AVANDIA": 0.2417150887459127, "BARACLUDE": 9.605478540840526, "BETMIGA": 1.0045146757949692, "BEVACIZUMAB": 0.5883528143631997, "BIKTARVY": 2.818647919224698, "BUPRENORPHINE": 0.2203654388780359, "BYDUREON": 0.3943823132732708, "BYETTA": 1.0059264167955548, "CANAGLIFLOZIN": 7.551182649665888, "CELECOXIB": 3.737386679172201, "CELLCEPT": 0.2257799574805451, "CICLOSPORIN": 0.1286260138934281, "CLOPIDOGREL": 0.5292476733269929, "COAPROVEL": 11.380374787915464, "COMBIVIR": 4.102785800585461, "COMIRNATY": 0.0062030318541151, "COMPETACT": 78.00036413067367, "CRIXIVAN": 13.556417406107396, "CYTARABINE": 0.6290589709570167, "DAPAGLIFLOZIN": 5.598691253071434, "DAPTOMYCIN": 4.658532419402796, "DARUNAVIR": 3.4786883114918337, "DEXAMETHASONE": 0.349194473059719, "DOLUTEGRAVIR": 4.342632317561691, "DULAGLUTIDE": 2.6397498231605625, "DULOXETINE": 0.819821300108701, "DUOPLAVIN": 35.72516020539575, "EFAVIRENZ": 3.869819696208984, "EFFICIB": 85.40520449294411, "ELIQUIS": 0.3479545134596383, "EMPAGLIFLOZIN": 10.105999062525663, "EMTRICITABINE": 4.4671318464322045, "EMTRIVA": 4.626745267934338, "ENTECAVIR": 6.878527305442215, "ENTRESTO": 0.179685038407224, "EPIVIR": 15.513690838318295, "ESOMEPRAZOLE": 4.459724969156753, "EUCREAS": 54.0076132996157, "EXFORGE": 0.6225814438576092, "EXJADE": 0.242474324174778, "FENTANYL": 0.4371613423748748, "FORXIGA": 3.477332015647255, "GALVUS": 2.8820989665033085, "GENVOYA": 2.432816034194554, "GLIBENCLAMIDE": 8.31553636135406, "GLUCAGON": 18.29339663212248, "HARVONI": 0.6394927912319537, "HEPSERA": 1.3192000665986932, "HUMALOG": 0.2178304321766955, "HYDROCORTISONE": 0.5790250638294617, "IBUPROFEN": 2.578609870747207, "INCIVO": 0.6177491191056412, "INDINAVIR": 10.615151331617422, "INSULATARD": 5.741622961994821, "INSULIN": 1.3226640794914288, "INVIRASE": 13.189574486225942, "INVOKANA": 4.822680612783729, "IRBESARTAN": 8.469649436089473, "ISENTRESS": 1.2703862253364713, "JAKAVI": 0.6845666509102972, "JANUMET": 13.052522291867492, "JANUVIA": 2.829537625628609, "JARDIANCE": 4.446225560304851, "KALETRA": 5.486092874780975, "KARVEZIDE": 11.08753621334067, "KEPPRA": 0.3618168874292448, "KYMRIAH": 0.9015021599510692, "LAMIVUDINE": 11.65414318888806, "LANTUS": 0.3674085875388562, "LEVEMIR": 0.961814857203177, "LEVETIRACETAM": 0.7876020623758714, "LIRAGLUTIDE": 2.659655997846512, "LYRICA": 0.3579518199015778, "METFORMIN": 37.51443785708738, "METHOTREXATE": 0.1836510938122575, "MICARDIS": 1.2672650571460728, "MICARDISPLUS": 7.595427151077852, "MIDAZOLAM": 1.2768126419549328, "NEVIRAPINE": 3.561322697959865, "NORVIR": 2.1900375161912287, "NOVONORM": 8.07938423012479, "OLANZAPINE": 0.1402671257298146, "OZEMPIC": 4.053035294571535, "PANTOPRAZOLE": 2.6446327572858004, "PEGASYS": 0.1774629642877837, "PEGINTRON": 0.2147083200417888, "PRITOR": 11.059916099594156, "RASILEZ": 1.461612094137502, "REPAGLINIDE": 20.635407602360583, "RIBAVIRIN": 0.7836739879706826, "RYBELSUS": 1.3024258560102646, "SAQUINAVIR": 30.76625312782692, "SITAGLIPTIN": 21.52830886033204, "SPIKEVAX": 0.0304068312405936, "SPIRONOLACTONE": 1.5202999408916484, "STAVUDINE": 59.73239803503783, "STRIBILD": 0.1457559618053281, "SUSTIVA": 10.085088378464995, "SUTENT": 0.1274689133620581, "TELMISARTAN": 1.569811387712367, "TENOFOVIR": 3.481036080947576, "TIVICAY": 2.584505602748674, "TOBRAMYCIN": 2.488585383059465, "TOZINAMERAN": 0.0161898636346412, "TRULICITY": 1.1339710238278229, "TRUVADA": 0.3893735774088441, "VELMETIA": 83.63659740336495, "VEMLIDY": 4.63161942658897, "VICTOZA": 1.7605112253849258, "VILDAGLIPTIN": 11.333772610235249, "VIRAMUNE": 3.731626853255287, "VIREAD": 5.014528573869841, "XARELTO": 2.555879522454513, "XIGDUO": 76.28632593236019, "ZERIT": 112.65864287560146, "ZOMARIST": 61.4950458281488, "null": 4.6507668806442295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6822.json
index a33033f07c5..60dbfd4175f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6822.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6822.json
@@ -1 +1 @@
-{"ELIQUIS": 6.149256689058482, "TAMIFLU": 31.368353476497735, "null": 1.88202276025813}
\ No newline at end of file
+{"LEVOFLOXACIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6823.json
index 186343491b5..0e7d8a4cb83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6823.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6823.json
@@ -1 +1 @@
-{"ELIQUIS": 3.1047072311038444, "KEPPRA": 2.1869702671416995, "TAMIFLU": 6.6192310343218805, "ZYPREXA": 2.8762673410982744, "null": 3.095984129282946}
\ No newline at end of file
+{"null": 0.6572227330518101}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6824.json
index 7aba2c3decf..dd161db73cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6824.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6824.json
@@ -1 +1 @@
-{"OLANZAPINE": 11.507858120138104, "ZYPREXA": 7.695042052797245, "null": 2.624762531110566}
\ No newline at end of file
+{"null": 1.5608023183884372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6825.json
index da0d0159bef..a838fec3f08 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6825.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6825.json
@@ -1 +1 @@
-{"AERIUS": 46.58721842142428, "LEVOFLOXACIN": 8.361147565363211, "PEGASYS": 3.3932990885150165, "null": 1.1052905625140488}
\ No newline at end of file
+{"CLOPIDOGREL": 1.6897898400581963, "COMIRNATY": 0.3133296529145949, "CYMBALTA": 1.020033710305683, "FLUTICASONE": 216.4316374980787, "GARDASIL": 6.460965124056082, "IMATINIB": 37.69640595005169, "ROTATEQ": 12.131904994862603, "SPIKEVAX": 0.1307570401841755, "SUTENT": 0.7821036995882791, "TASIGNA": 6.415649433206307, "VAXZEVRIA": 0.0903772979328053, "XELJANZ": 2.913085691368192, "null": 1.9278324518349752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6826.json
index 4f9be395d62..a17d9e1046e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6826.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6826.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.934934147561611, "ABATACEPT": 1.3386442547665198, "ADENURIC": 3.276291395375459, "AERIUS": 2.361609636502864, "AFATINIB": 1.7227812942878713, "AIMOVIG": 1.3629438884542802, "ALDARA": 1.7499282095602338, "ALIMTA": 1.071927759442468, "ANTHRAQUINONE": 27.77970820789924, "AP": 9.156194915220588, "APROVEL": 1.1154084876460444, "ARIXTRA": 1.5105384224715994, "ARZERRA": 1.0840318494656145, "BESREMI": 5.596282910433106, "BETMIGA": 1.625837750709491, "BINOCRIT": 3.5176137602039232, "BOCEPREVIR": 1.3013930479866356, "BRILIQUE": 1.5278342789853498, "BRINTELLIX": 5.376291387266709, "BUVIDAL": 1.1293610962369682, "CEFUROXIME": 1.4059981562113415, "CELSENTRI": 1.9567728388236485, "CHLORHEXIDINE": 4.717334957408566, "CIMZIA": 1.9858677471613704, "CIRCADIN": 1.2042188670348652, "CLOPIDOGREL": 1.4857564002626262, "COAPROVEL": 1.2089873708386092, "COMPRESSION": 4.944102466946936, "CONTRAST": 1.8168314156273453, "COSENTYX": 1.512947593836859, "CUBICIN": 1.005673886167324, "DAKLINZA": 1.1725899646439195, "DESLORATADINE": 2.2775029291853244, "DUAKLIR": 4.433357667806532, "DUKORAL": 1.163877499255205, "DUPIXENT": 1.6774122329203056, "ELIQUIS": 1.0226269815435038, "ELOCTA": 1.6309222779371613, "EMEND": 1.525515010190853, "ENTECAVIR": 1.3635906604253314, "ENTRESTO": 2.2049266412573343, "ERELZI": 1.0823074826630816, "ERLEADA": 1.9040508229676465, "ESBRIET": 1.459655220062024, "EUCREAS": 2.62907971593626, "EVRA": 1.244697803272168, "EXFORGE": 1.149302192719634, "EXVIERA": 3.196564920252836, "FASENRA": 1.5399456628956014, "FASTURTEC": 1.1127343280802795, "FEBUXOSTAT": 1.4310864870810631, "FIASP": 1.041483143214781, "FLEBOGAMMA": 1.5953751470239124, "FLUCELVAX": 2.035750448817452, "FORXIGA": 1.3244686343707075, "GALVUS": 2.091835421999153, "GEFITINIB": 1.0894384225652805, "GREPID": 1.8580054514151865, "HERCEPTIN": 1.0665779143431735, "HIZENTRA": 1.5029942568341208, "HYDROCHLOROTHIAZIDE": 1.0769337024900911, "HYDROCORTISONE": 1.1798205429448492, "HYQVIA": 1.445079963165662, 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4.010183949524811, "RIXATHON": 4.361945542553429, "ROACTEMRA": 1.9203192027321887, "SHINGRIX": 2.4041225153954917, "SILODOSIN": 1.664327169073092, "SILODYX": 1.6927716311152046, "SKYRIZI": 1.958512003471, "SOVALDI": 1.1772818300450003, "STELARA": 1.044400150335166, "STOCRIN": 2.450197395109578, "SUSTIVA": 1.8281215956530408, "SYMTUZA": 2.458791050041042, "TAFINLAR": 1.0026730996986235, "TASIGNA": 1.1816646311826822, "TELAPREVIR": 2.5581591849985323, "TOUJEO": 1.5223737439312452, "TOZINAMERAN": 1.0696829192572577, "TREMFYA": 1.087887603916094, "TRESIBA": 1.5741793076177677, "TWINRIX": 1.3843812877003978, "UROREC": 2.070639017654329, "VECTIBIX": 1.0801814057173893, "VELMETIA": 1.0831690326062435, "VEMURAFENIB": 1.0820400408107451, "VIRAMUNE": 1.415193117887577, "VORTIOXETINE": 2.706056077599857, "XOLAIR": 2.642180799900074, "YERVOY": 1.7669734154287375, "ZARZIO": 2.4757848287068525, "ZELBORAF": 1.8238976795117827, "ZIAGEN": 1.766172695754329, "ZYCLARA": 1.5911321914465055, "ZYLLT": 7.78500757438934, "null": 1.7402989399631796}
\ No newline at end of file
+{"AVANDAMET": 11.344734333160911, "AVANDIA": 16.58420049389253, "CLOPIDOGREL": 1.8781044762970744, "COMIRNATY": 0.4383197838640882, "CYMBALTA": 1.1337075259633465, "ELIQUIS": 2.076874043910047, "EVENITY": 33.699373431212905, "EYLEA": 10.414512681061057, "FORXIGA": 6.239252837874376, "JARDIANCE": 3.910127593967568, "NEXAVAR": 3.2938767148953887, "PEGASYS": 0.7871605008407673, "PEGINTRON": 2.118287269868794, "PLAVIX": 1.8594417244860544, "SPIKEVAX": 0.2732184465183608, "VAXZEVRIA": 0.381090021763456, "null": 0.9810707110224796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6827.json
index 38c9e033f2b..0ec4491dfe7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6827.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6827.json
@@ -1 +1 @@
-{"ARAVA": 2.804497435681925, "ENBREL": 21.743634121495617, "null": 1.288434297715008}
\ No newline at end of file
+{"COMIRNATY": 0.8977525241272523, "SPIKEVAX": 0.9997502421789208, "VAXZEVRIA": 2.094601051895581, "null": 0.1681703264445696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6828.json
index 185abb7ec1e..b16ef0926aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6828.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6828.json
@@ -1 +1 @@
-{"AIMOVIG": 1.7835311240445637, "APIXABAN": 8.592697110992848, "ELLAONE": 17.2964921881521, "EMPAGLIFLOZIN": 25.75357746727545, "FORXIGA": 85.30780393204091, "JARDIANCE": 111.44988062790392, "SUTENT": 1.3009329102405294, "VIAGRA": 2.9465436143331285, "null": 1.0900380999922636}
\ No newline at end of file
+{"COMIRNATY": 0.9647868605861514, "SPIKEVAX": 0.7793158914071653, "TOZINAMERAN": 1.4986461651238352, "VAXZEVRIA": 0.3779472845049668, "null": 1.5757456168574515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6829.json
index c130b169da8..3689bc26019 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6829.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6829.json
@@ -1 +1 @@
-{"EVENITY": 261.59813408667446}
\ No newline at end of file
+{"CLADRIBINE": 353.5099699955909, "MERCAPTOPURINE": 311.1436128783783, "null": 0.7715003486009308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/683.json
index 75c2c850114..b807a0aa6a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/683.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/683.json
@@ -1 +1 @@
-{"COMIRNATY": 2.9583985515168583, "COVID19": 1.5007802844855342, "GARDASIL": 4.487941083354287, "SPIKEVAX": 1.7695236717511895, "TOZINAMERAN": 3.60862233528396}
\ No newline at end of file
+{"ADALIMUMAB": 0.7051213333964965, "AMGEVITA": 77.00569225346163, "ANAKINRA": 2.234909888724937, "ARAVA": 2.2825464578450743, "ATEZOLIZUMAB": 32.77299868244631, "CELECOXIB": 4.722041006679708, "CIMZIA": 77.0656137026122, "COMIRNATY": 0.4614421869171145, "COSENTYX": 42.781363356957634, "EMPAGLIFLOZIN": 5.361573722202103, "ENBREL": 7.836217888321912, "ENTYVIO": 4.698751837196362, "ETANERCEPT": 17.506190823212762, "HUMIRA": 11.309667062130446, "METHOTREXATE": 1.8802367341755537, "RINVOQ": 2.740502188036837, "SIMPONI": 53.87304493530668, "SPIKEVAX": 0.1717307535661165, "STELARA": 2.6271204981734977, "TOZINAMERAN": 0.2369670455329043, "TREMFYA": 2.776067441599327, "VAXZEVRIA": 0.18779839586885, "XELJANZ": 2.155713088588961, "null": 0.1470129887471324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6830.json
index 18b1cc3b4a7..22133b9cb71 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6830.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6830.json
@@ -1 +1 @@
-{"BUDESONIDE": 15.599294521545328, "RITONAVIR": 570.5118041624851, "null": 1.8486214868391624}
\ No newline at end of file
+{"COMIRNATY": 1.797022889908282, "GARDASIL": 0.7893567630356745, "INFANRIX": 8.110883309480084, "KEPPRA": 2.3187420766960694, "LEVETIRACETAM": 5.664683744393851, "ROTASHIELD": 167.08595571253818, "SPIKEVAX": 1.098496484213899, "TOZINAMERAN": 0.1804068182378785, "VAXZEVRIA": 0.5023011240817025, "ZYPREXA": 1.2783170219026074, "null": 1.9856990914102717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6831.json
index a42b840ce93..bcf3f798f70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6831.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6831.json
@@ -1 +1 @@
-{"null": 6.149057498512275}
\ No newline at end of file
+{"null": 0.8543727500275625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6832.json
index 001d4c0cf7b..0c824fe67b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6832.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6832.json
@@ -1 +1 @@
-{"NOXAFIL": 411.6086505306429, "POSACONAZOLE": 792.8375288062289, "null": 1.389376939580893}
\ No newline at end of file
+{"BYETTA": 121.00273941163998, "null": 0.4772793874135558}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6833.json
index a4823d5b35d..b37ad5b46b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6833.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6833.json
@@ -1 +1 @@
-{"PEMETREXED": 1527.0649025067391}
\ No newline at end of file
+{"BYETTA": 31.393207565366254, "CICLOSPORIN": 10.004333977557652, "ELIQUIS": 2.6758922297475154, "HUMIRA": 14.796769543581776, "JANUMET": 11.898099650174643, "JANUVIA": 26.279891388220648, "ROTATEQ": 149.57965230494827, "null": 0.937563248878432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6834.json
index 9f3523001b9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6834.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6834.json
@@ -1 +1 @@
-{"null": 2.567861733067455}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6835.json
index eef2109873a..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6835.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6835.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 128.3624554030931, "HALAVEN": 176.10370880440905}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6836.json
index 4ece481e629..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6836.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6836.json
@@ -1 +1 @@
-{"ESOMEPRAZOLE": 215.6324427323596, "null": 1.097745090481706}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6837.json
index 215b7c50d62..d3216d1d882 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6837.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6837.json
@@ -1 +1 @@
-{"EYLEA": 1820.0005019124112}
\ No newline at end of file
+{"ABILIFY": 12.72705516851472, "HUMALOG": 18.64954912545092, "KEPPRA": 4.936251480815301, "null": 1.6901776341599788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6838.json
index 387937aa441..24bb8c32e37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6838.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6838.json
@@ -1 +1 @@
-{"null": 1.120368689581554}
\ No newline at end of file
+{"null": 0.2596972743864258}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6839.json
index 7b9a914e041..d40eda622b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6839.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6839.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"BRILIQUE": 15.55383679062142, "CLOPIDOGREL": 6.708598971227058, "COMIRNATY": 0.0698696363960674, "ELIQUIS": 18.39021277998263, "KEYTRUDA": 2.119981023334966, "NEXAVAR": 4.913895639642781, "PLAVIX": 15.84363446168183, "SUTENT": 1.5791464059113698, "XARELTO": 15.773913364199675, "null": 1.0286193097804044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/684.json
index 2959c899a7b..b9d54bf3531 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/684.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/684.json
@@ -1 +1 @@
-{"ANAKINRA": 214.09990399409415, "ARAVA": 8.73150413354774, "CIMZIA": 14.20421949429828, "COSENTYX": 19.113289327343, "ENBREL": 14.831745069338524, "HUMIRA": 8.826519533944474, "METHOTREXATE": 14.677417560233964}
\ No newline at end of file
+{"CELLCEPT": 6.1450989340539, "CICLOSPORIN": 6.825141832583513, "COMBIVIR": 37.16774233533396, "COMIRNATY": 0.2093733801382261, "GARDASIL": 72.65606894254631, "KALETRA": 55.25009863770435, "SILGARD": 347.5575008371184, "STELARA": 5.7193662850465445, "null": 0.2805593341323424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6840.json
index 2bc221a97b0..dbf2d37def0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6840.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6840.json
@@ -1 +1 @@
-{"CICLOSPORIN": 20.223403042777708, "null": 2.4473951292315634}
\ No newline at end of file
+{"BEVACIZUMAB": 15.052426923308412, "LONSURF": 35.05839673789991, "OLANZAPINE": 10.07275337447502, "PEGASYS": 1.9529944831177144, "null": 1.3031795535179358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6841.json
index 93f4efd2645..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6841.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6841.json
@@ -1 +1 @@
-{"AMIKACIN": 6.97841915403745, "CELLCEPT": 4.966337751243146, "DIFICLIR": 47.81509754634903, "LEVOFLOXACIN": 15.050348217150509, "PANTOPRAZOLE": 7.692721310931113, "PEGINTRON": 1.0060189620392588, "TIGECYCLINE": 42.06122203494714, "TOBRAMYCIN": 46.61018151627578, "VFEND": 4.923921244898617, "null": 7.123662467324542}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6842.json
index 4ec77646d71..115f68779b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6842.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6842.json
@@ -1 +1 @@
-{"AZACITIDINE": 68.5374381551583, "CICLOSPORIN": 6.206217235159014, "METHOTREXATE": 22.140759919258784}
\ No newline at end of file
+{"JANUMET": 45.90470723642693, "null": 1.403982565750079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6843.json
index 62dd6a2b94a..742d48169e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6843.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6843.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 14.667354594778637, "ASPARAGINASE": 319.775220112462, "BUSILVEX": 174.78341325570173, "BUSULFAN": 13.548186059616684, "CELLCEPT": 4.085297372411056, "CICLOSPORIN": 11.934815144922675, "CYTARABINE": 17.012471858250922, "DEXAMETHASONE": 7.035359288062929, "IBUPROFEN": 6.352531771174996, "ONCASPAR": 32.13838074555922, "SOLIRIS": 12.840627580830272}
\ No newline at end of file
+{"CIMZIA": 11.22658337565087, "ENTYVIO": 38.96286973590514, "HUMIRA": 27.73004454727307, "STELARA": 17.176690807547143, "null": 0.6534009340624118}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6844.json
index d916991eb6d..4644ea485cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6844.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6844.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 15.67225481119778, "AMIKACIN": 22.172232147919782, "APIXABAN": 1.3686127581567848, "ASPARAGINASE": 12.415466277968063, "AZTREONAM": 65.86105513431144, "BASILIXIMAB": 23.609301228922348, "BENRALIZUMAB": 81.75161960364622, "BUSULFAN": 6.907619324354034, "CASPOFUNGIN": 32.45388870286651, "CELLCEPT": 4.114204383274852, "CICLOSPORIN": 11.263638566533045, "CYTARABINE": 12.371061814410146, "DEXAMETHASONE": 6.617214001138983, "DOXORUBICIN": 3.812937353762629, "EXJADE": 1.5805926948000562, "FENTANYL": 1.286142721768603, "GANCICLOVIR": 12.41252544005707, "HIZENTRA": 5.671568869839827, "HUMIRA": 2.792358891822872, "IBUPROFEN": 3.1410134279904565, "KAFTRIO": 10.942568534312135, "KALYDECO": 30.343285991339783, "LEVOFLOXACIN": 4.15307960907002, "METHOTREXATE": 1.9925385469130563, "MYCOPHENOLATE": 23.508561960276364, "ORKAMBI": 59.52932317879984, "REMICADE": 7.224403936982364, "RITUXIMAB": 3.249586449277101, "SOLIRIS": 6.825609567625249, "SPINRAZA": 8.923477398241392, "TOBRAMYCIN": 51.875778004570485, "TRACLEER": 1.9134686213044036, "TRELEGY": 3.29997373638286, "VORICONAZOLE": 4.730976282542804, "XOLAIR": 1.1717374517320758}
\ No newline at end of file
+{"ARAVA": 0.4903630803106946, "BRAFTOVI": 37.64028857281047, "CELLCEPT": 6.607967245077647, "CICLOSPORIN": 2.868040624680952, "CLOPIDOGREL": 2.219301720234147, "COSENTYX": 2.8412783935195645, "ELIQUIS": 1.0691231254417704, "ENTYVIO": 11.656347346359956, "GANCICLOVIR": 18.840331831147857, "HUMIRA": 4.735650146328456, "PLAVIX": 2.460863928126959, "SUTENT": 1.1504180709089935, "null": 1.765509858201804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6845.json
index 0b3339782eb..aa9ea658174 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6845.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6845.json
@@ -1 +1 @@
-{"DARZALEX": 214.1076754529604, "null": 2.6961666124093897}
\ No newline at end of file
+{"null": 0.8349763786897797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6846.json
index f9585b4a2ab..18fe3972169 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6846.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6846.json
@@ -1 +1 @@
-{"null": 2.47292729852726}
\ No newline at end of file
+{"ZOSTAVAX": 41.41191692948338, "null": 1.4737406591636295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6847.json
index 81fedae6fff..7025ca5f855 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6847.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6847.json
@@ -1 +1 @@
-{"ZOSTAVAX": 122.53392502395144}
\ No newline at end of file
+{"null": 1.4902151349234876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6848.json
index 128a8fec110..deca5047b0f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6848.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6848.json
@@ -1 +1 @@
-{"VFEND": 128.6672897321775, "VORICONAZOLE": 300.1623556152388, "null": 1.5275890267406491}
\ No newline at end of file
+{"COMIRNATY": 0.1133991462529931, "NEVIRAPINE": 118.8266648491754, "XELJANZ": 4.496822742690647, "null": 1.401210401752681}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6849.json
index 7b9a914e041..9ac2e216d7a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6849.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6849.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"null": 0.925299144556582}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/685.json
index ae9a4eb0787..4b5f39075e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/685.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/685.json
@@ -1 +1 @@
-{"ABATACEPT": 14.998149458397153, "ACETAMINOPHEN": 17.368259943870395, "ACETYLSALICYLIC": 16.52024151786227, "ADALIMUMAB": 22.016648906359464, "ADVATE": 1.9608579087639808, "AIMOVIG": 1.0118230233319534, "AMINOSALICYLIC": 2.329512758318693, "ANAKINRA": 13.007647934214392, "APREMILAST": 12.876044526087918, "APREPITANT": 21.884931133281384, "ARAVA": 25.81598372032629, "AZATHIOPRINE": 1.2358166911443134, "BELIMUMAB": 5.827965804454518, "CELECOXIB": 1.4892654803906926, "CIMZIA": 4.305032573210535, "COSENTYX": 3.7602168578615736, "DULOXETINE": 1.0023690254641382, "ELIQUIS": 3.3169195186283607, "ENBREL": 7.210858829302754, "ERELZI": 4.703859815865795, "ETANERCEPT": 1.5512558014903477, "EVISTA": 1.2343211165216714, "GLYCOPYRRONIUM": 1.5815440786454418, "HEMLIBRA": 1.5054037364451742, "HUMIRA": 2.630172971784552, "LANTUS": 1.186458731675489, "LEFLUNOMIDE": 2.899907381522649, "LYRICA": 1.4546807318418091, "METHOTREXATE": 1.765228047928043, "MYCOPHENOLATE": 1.379849968289686, "OCEAN": 17.62765613959282, "ORENCIA": 2.3308015051993154, "REMICADE": 1.1248057416591215, "RINVOQ": 1.734952389549951, "RITUXIMAB": 2.5598916915263383, "SIMPONI": 1.423273675772991, "SKYRIZI": 1.4166013358010154, "STELARA": 1.398789291279147, "SUBOXONE": 1.159980081662207, "TOVIAZ": 1.5614990669014193, "TREMFYA": 1.5877267634933931, "VIAGRA": 2.790431530259921, "XELJANZ": 3.1563723529350804, "ZOMETA": 2.430895632992411}
\ No newline at end of file
+{"null": 4.815869617115221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6850.json
index 1229283274b..4b5fe6c8ddf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6850.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6850.json
@@ -1 +1 @@
-{"KEYTRUDA": 4.578429259945913, "PEGASYS": 4.096950187522695, "PEGINTRON": 8.689713970945844}
\ No newline at end of file
+{"ALIMTA": 3.800956215802575, "ARAVA": 0.1820181009696454, "AVASTIN": 43.0489168396272, "AZATHIOPRINE": 4.6661911854694775, "BEVACIZUMAB": 22.392575750646863, "CABOMETYX": 9.63845076714197, "CELLCEPT": 3.4287765059025275, "CICLOSPORIN": 2.3465383715558032, "COMIRNATY": 0.0365672084703633, "DEXAMETHASONE": 3.5681964743774346, "DOCETAXEL": 4.96821987938351, "ENTYVIO": 3.027198750737247, "IPILIMUMAB": 14.1312095025065, "KEYTRUDA": 4.592907668234061, "LENVIMA": 11.66486718706894, "NEXAVAR": 4.894418353014849, "OPDIVO": 3.873264263300012, "PLAVIX": 1.2592674887557385, "RINVOQ": 3.0552950423669656, "ROACTEMRA": 23.015201243826013, "STELARA": 1.7768150256667463, "STIVARGA": 3.2184559359953058, "SUTENT": 2.8046291593743256, "TOCILIZUMAB": 34.58447319617437, "VOTRIENT": 5.960899245118172, "XELJANZ": 1.6108000744492903, "YERVOY": 33.74146528597284, "null": 0.992745251376066}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6851.json
index 78d325ce5dd..217a6873a07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6851.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6851.json
@@ -1 +1 @@
-{"ABACAVIR": 22.82069497717423, "ADALIMUMAB": 1.560347027567404, "AMGEVITA": 46.48257774633006, "ANAKINRA": 2.0365221602968604, "APREMILAST": 1.6825195823750554, "AVONEX": 3.651217352739838, "BRODALUMAB": 38.37623437383036, "CARIPRAZINE": 9.92761212615132, "CELECOXIB": 2.4001400884204487, "CHAMPIX": 1.1331116181480096, "CICLOSPORIN": 4.6271820930632535, "CIMZIA": 10.59522853520784, "COSENTYX": 39.92569355554707, "DAPAGLIFLOZIN": 6.38472549246734, "DUPIXENT": 3.623032255377798, "EMPAGLIFLOZIN": 1.6786122625399438, "ENBREL": 7.020498072099405, "ENTYVIO": 1.9774354568130597, "GOLIMUMAB": 17.33678070325074, "GUSELKUMAB": 19.823778766041663, "HUMIRA": 13.291624687832163, "HYDROCORTISONE": 1.3819265695831289, "IDACIO": 25.684053552221773, "INFLIXIMAB": 4.077207811533406, "IVABRADINE": 22.570009125551728, "KEYTRUDA": 1.606302771809595, "LEFLUNOMIDE": 3.532014189991952, "MAVENCLAD": 1.8793148736796488, "METHOTREXATE": 4.477999324788413, "OTEZLA": 38.38255102083125, "PEGASYS": 2.3397961595430514, "PEGINTERFERON": 2.5079651191003878, "PEGINTRON": 1.3165271681672537, "PEMBROLIZUMAB": 2.412262972984238, "REMICADE": 4.827795061340399, "RINVOQ": 3.5421088835381243, "RISANKIZUMAB": 64.94692932419719, "ROACTEMRA": 2.2858492251678544, "SIMPONI": 8.804527773910243, "SKYRIZI": 52.788970015310994, "STELARA": 45.92494760760212, "TOCILIZUMAB": 1.6827700365998786, "TREMFYA": 56.59738025111589, "USTEKINUMAB": 19.47108059867133, "XELJANZ": 1.0290645829606428, "ZINBRYTA": 5.849242037953012}
\ No newline at end of file
+{"BYETTA": 4.831315081878024, "CHLORMETHINE": 157.44829188806528, "CICLOSPORIN": 0.4702047492617207, "CLOPIDOGREL": 1.3426473835833153, "COMIRNATY": 0.0204260497068435, "ELIQUIS": 3.2652553827927577, "ENTYVIO": 4.296989141754599, "HUMALOG": 1.4344655956302272, "HUMIRA": 1.488940660295141, "JANUMET": 8.456374996632215, "JANUVIA": 4.495401065837074, "PANTOPRAZOLE": 12.95838365711935, "PEGASYS": 0.6746433000554172, "PEGINTRON": 0.9433711747908806, "PLAVIX": 0.9683404354874736, "STELARA": 1.143992642673168, "VIAGRA": 2.0837684194102715, "XELJANZ": 1.0894350571638336, "ZOSTAVAX": 8.158664702341628, "ZYPREXA": 0.54265287318276, "null": 4.933531275773745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6852.json
index 4d40444ee76..f3ee0e393b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6852.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6852.json
@@ -1 +1 @@
-{"CICLOSPORIN": 17.632460627415607, "COSENTYX": 80.19648950652187, "STELARA": 97.88198677088477, "TREMFYA": 113.34041673486207}
\ No newline at end of file
+{"LANTUS": 3.934631118869082, "STELARA": 7.892603974328329, "null": 1.316510433329206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6853.json
index b72b3d3264f..97c75cd9146 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6853.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6853.json
@@ -1 +1 @@
-{"ABATACEPT": 3.3826314681527347, "ADALIMUMAB": 15.646597914898898, "APREMILAST": 25.479445587990757, "ARAVA": 9.548644909845526, "AZATHIOPRINE": 1.149422825260478, "CELECOXIB": 2.99949996631996, "CICLOSPORIN": 1.7394084963461416, "CIMZIA": 15.422106312276972, "COSENTYX": 48.11329056998748, "DULOXETINE": 1.349575803408862, "ENBREL": 4.827931991596277, "ERELZI": 6.785098643149864, "ESOMEPRAZOLE": 1.0392823363785508, "ETANERCEPT": 5.280557119405412, "GOLIMUMAB": 8.370060998611207, "HUMIRA": 9.390486611940275, "HYDROCORTISONE": 1.8251130524551529, "LEFLUNOMIDE": 13.375046521121352, "METHOTREXATE": 6.121017501358987, "OTEZLA": 26.592657008632838, "REMICADE": 1.882203276371208, "RINVOQ": 3.210766460606365, "RISANKIZUMAB": 24.8556723405198, "SIMPONI": 16.789623502663087, "SKYRIZI": 11.436602027411512, "STELARA": 29.7299817903874, "TREMFYA": 95.32419704938978, "USTEKINUMAB": 32.492689241697285, "XELJANZ": 1.9393005152522789}
\ No newline at end of file
+{"DASABUVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6854.json
index ac3e2caa0c4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6854.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6854.json
@@ -1 +1 @@
-{"ABILIFY": 9.615305348013736, "ARIPIPRAZOLE": 7.010423144443448, "ATAZANAVIR": 864.076421109176, "CHAMPIX": 5.554664792548061, "ENFUVIRTIDE": 296.7536430572005, "ISENTRESS": 43.94282658421839, "KEPPRA": 5.983303759077355, "LATUDA": 8.074227299509102, "OLANZAPINE": 14.85222806556086, "RALTEGRAVIR": 663.2396778811935, "ZYPREXA": 8.906618439569613}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6855.json
index 688884b7e4c..8b47c3733f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6855.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6855.json
@@ -1 +1 @@
-{"ABILIFY": 5.616737573158261, "ARIPIPRAZOLE": 2.927547562623122, "BIKTARVY": 2.997034679642722, "CHAMPIX": 10.780484138968731, "COMTAN": 15.043310369274588, "CYMBALTA": 1.079638990095739, "DOLUTEGRAVIR": 29.68566372575558, "FENTANYL": 2.146924073746344, "FYCOMPA": 8.522408418008784, "IBRANCE": 1.9126567445927587, "KALETRA": 3.2095535039873906, "KEPPRA": 2.3921006799074, "LATUDA": 15.73146219237784, "LEVETIRACETAM": 7.15761083068843, "LYRICA": 1.8421324682247195, "NUCALA": 5.279707138902394, "OLANZAPINE": 5.079072930928464, "PANTOPRAZOLE": 3.35382497446061, "PEGASYS": 1.4917743932836192, "PEGINTRON": 3.281670866273176, "TAMIFLU": 7.817796259819365, "VFEND": 4.058998513201081, "XEPLION": 61.4738604159204, "ZYPREXA": 6.873586095912122, "null": 1.8589115838848087}
\ No newline at end of file
+{"NAGLAZYME": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6856.json
index 0d7219567f7..3347221b57d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6856.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6856.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0928794187938264, "CYMBALTA": 4.744806210036919, "GARDASIL": 8.852669974974052, "KEPPRA": 13.898352664844046, "LEVETIRACETAM": 19.69329021393718}
\ No newline at end of file
+{"COMIRNATY": 1.0586420285640783, "SPIKEVAX": 0.2782986894335099, "VAXZEVRIA": 0.1771957912829437, "null": 2.648312341538713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6857.json
index 334e8e9046e..fb562c637c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6857.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6857.json
@@ -1 +1 @@
-{"PLAVIX": 36.87053850096279, "TAXOTERE": 231.20972511778865, "null": 1.5118494188507938}
\ No newline at end of file
+{"ADALIMUMAB": 1.6275363240086715, "ARAVA": 12.694111910741034, "NUCALA": 12.049593771334049, "null": 1.2018064950161969}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6858.json
index abf6e93e5d7..25afcd541db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6858.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6858.json
@@ -1 +1 @@
-{"ABILIFY": 4.158956068754716, "AERIUS": 5.578688781074466, "ARIPIPRAZOLE": 5.782475623119649, "AVAMYS": 2.1886475041574243, "BRINTELLIX": 6.781936190857386, "BRIVIACT": 7.345755108065209, "BUPRENORPHINE": 1.0617195892469895, "CHAMPIX": 2.0408074117008197, "COMTAN": 13.854426122129828, "CYMBALTA": 2.233385698802848, "EBIXA": 6.641989223716157, "ENTACAPONE": 8.649524864319838, "FAMPYRA": 1.989193839145918, "FENTANYL": 1.954399778575998, "FIRDAPSE": 2.2369151359801256, "FYCOMPA": 4.176428754160562, "INFANRIX": 4.009263813939239, "KAFTRIO": 5.676928787233578, "KEPPRA": 5.177193687818671, "LATUDA": 5.52750750606705, "LEVETIRACETAM": 5.535546376860114, "LYRICA": 2.1981642587290597, "MEMANTINE": 7.743706531478124, "MIDAZOLAM": 5.474875171976252, "OLANZAPINE": 5.808412534572094, "PEGINTRON": 1.2621327280742862, "SIFROL": 17.707000380016478, "STALEVO": 11.440689702563777, "SUBOXONE": 4.9783731932162, "SYCREST": 13.140979296140326, "TAMIFLU": 2.567700717582952, "VFEND": 1.4657063310968903, "XYREM": 3.042851549867131, "ZYPADHERA": 18.42425375766652, "ZYPREXA": 3.7529999391417967, "null": 3.3263442136579977}
\ No newline at end of file
+{"COMIRNATY": 0.2921455767731519, "null": 4.584070876546053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6859.json
index a006133c257..0d2ac78bc1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6859.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6859.json
@@ -1 +1 @@
-{"ABILIFY": 4.697350117455549, "ARIPIPRAZOLE": 9.64387681118675, "ATAZANAVIR": 40.67810696512076, "KEPPRA": 2.75442779602126, "LEVETIRACETAM": 2.175933810464027, "OLANZAPINE": 12.185465414783588, "ZYPREXA": 5.2300472652238135, "null": 3.975188774102112}
\ No newline at end of file
+{"null": 1.80462367809423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/686.json
index ffa142ce22c..fa8c804875b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/686.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/686.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 12.697509728922162, "BUDESONIDE": 2.5485373583746287, "CELECOXIB": 29.73875828067373, "CICLOSPORIN": 5.612405568893792, "CIMZIA": 1.4650828539784713, "COSENTYX": 2.0050481045629764, "CYMBALTA": 1.7701145689357367, "ENBREL": 3.0598672708087853, "GARDASIL": 1.860666574861835, "HUMALOG": 2.278627136169689, "HUMIRA": 2.992104373090342, "IBRANCE": 4.026229544770969, "OMALIZUMAB": 4.1974747059302215, "RITUXIMAB": 3.4820277293417083, "SIMPONI": 4.816677640187761, "STELARA": 2.9130739977496747, "XELJANZ": 4.091048236158095, "ZOSTAVAX": 13.504660987059625}
\ No newline at end of file
+{"null": 4.344079692273116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6860.json
index b1b97ca9184..c17a881a6e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6860.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6860.json
@@ -1 +1 @@
-{"ABILIFY": 4.582932270202171, "ATAZANAVIR": 301.9021919157425, "BUPRENORPHINE": 2.2454057652861805, "ENFUVIRTIDE": 135.3868717632304, "INFANRIX": 17.122759786610846, "KEPPRA": 4.903634329965175, "LEVETIRACETAM": 2.5014008895168494, "MMRVAXPRO": 1.3957471703696571, "OLANZAPINE": 1.9602402281232167, "null": 3.3285856712335136}
\ No newline at end of file
+{"null": 2.354342172759579}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6861.json
index 2410bb49669..ead90d2dad1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6861.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6861.json
@@ -1 +1 @@
-{"null": 1.2687455096402631}
\ No newline at end of file
+{"ELIQUIS": 18.35617751377324, "null": 1.2300719843678736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6862.json
index 6f225b5daa8..69f96c00b82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6862.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6862.json
@@ -1 +1 @@
-{"null": 3.500420499157024}
\ No newline at end of file
+{"MEKINIST": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6863.json
index bd383f8d85c..5ab16defe05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6863.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6863.json
@@ -1 +1 @@
-{"BUMETANIDE": 171.91699021283188, "BUPRENORPHINE": 8.004819329406565, "CHAMPIX": 9.268239703141166, "COMTAN": 51.64729196331477, "CYMBALTA": 2.699021846482917, "FENTANYL": 5.729701530413742, "KEPPRA": 5.496445119786614, "OLANZAPINE": 10.31930889480686, "null": 1.691823373332985}
\ No newline at end of file
+{"COMIRNATY": 2.2931803103077657, "null": 0.5921261929123484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6864.json
index 59fa73d1899..1fa68facb40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6864.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6864.json
@@ -1 +1 @@
-{"ABILIFY": 17.89131769235133, "ACLIDINIUM": 17.783332048865734, "AERIUS": 2.172102247015496, "AMINOSALICYLIC": 3.278958317852486, "ANORO": 1.1252149785264294, "APTIVUS": 9.227838194335083, "ARIPIPRAZOLE": 16.530663174878203, "ATAZANAVIR": 41.69863048539939, "BEDAQUILINE": 5.280063674277921, "BETAFERON": 1.8573898352554823, "BRINTELLIX": 1.6576826717719526, "BRIVARACETAM": 3.146909279314742, "BRIVIACT": 13.540948584665262, "BUMETANIDE": 5.855314795899114, "BUPRENORPHINE": 2.1640287058647862, "CANAGLIFLOZIN": 16.020176613031254, "CANNABIDIOL": 8.818956485500166, "CARBIDOPA": 9.285230648564603, "CHAMPIX": 13.42769021943612, "COMTAN": 4.474774417384658, "CYMBALTA": 1.8387849443373527, "DAKLINZA": 4.714687668640631, "DELAMANID": 2.834763831293116, "DULOXETINE": 1.43056804296186, "ENFUVIRTIDE": 21.41372563484233, "EPCLUSA": 2.4212661204007366, "FENTANYL": 1.165108244580584, "FYCOMPA": 16.435413817933814, "HARVONI": 1.5621183661307525, "INTRONA": 2.4154655399077165, "INVEGA": 8.494303453081656, "KALETRA": 1.0220954307670889, "KEPPRA": 8.429291647987737, "LACOSAMIDE": 3.3460934829432505, "LATUDA": 10.779290717492495, "LEVETIRACETAM": 6.390337489606312, "LEVODOPA": 10.037793525066412, "LEVOFLOXACIN": 1.1538740565185297, "LURASIDONE": 8.879112032409159, "MIDAZOLAM": 1.1846778827124116, "NOT": 1.6323099043432352, "OLANZAPINE": 10.875990363254797, "OLYSIO": 1.626944998189776, "OXYBUTYNIN": 4.930518849582636, "PANTOPRAZOLE": 1.0058511906351908, "PEGASYS": 4.165478632477139, "PEGINTERFERON": 3.820405327661158, "PEGINTRON": 4.740014972610066, "REAGILA": 11.141630954124706, "REBETOL": 3.749073537722911, "RIBAVIRIN": 3.5022921063778685, "RISPERIDONE": 8.139262409338215, "SIFROL": 4.195641263478115, "STALEVO": 4.340717643291604, "SUBOXONE": 2.4896395243094345, "TAMIFLU": 3.7222431832637297, "TIVICAY": 2.9926273487737465, "TRIUMEQ": 3.3703636962415144, "VALSARTAN": 2.052873492381321, "VARENICLINE": 8.623899064165924, "VFEND": 1.935437845458819, "VIGABATRIN": 8.19166123294794, "VIMPAT": 5.068324218192024, "XEPLION": 20.386707798002, "XYREM": 5.2358790165350255, "ZONISAMIDE": 7.525407504306917, "ZYPADHERA": 6.155587087679568, "ZYPREXA": 8.378843721672734, "null": 1.8207358953938804}
\ No newline at end of file
+{"null": 1.7824481621550474}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6865.json
index 8dd9d59bfb6..d200a60533d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6865.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6865.json
@@ -1 +1 @@
-{"ABILIFY": 32.83947208469103, "ARIPIPRAZOLE": 45.83573673100216, "KEPPRA": 2.809785918185543, "LATUDA": 37.1786391081467, "LURASIDONE": 221.79228294144903, "OLANZAPINE": 39.66808173952492, "SUBOXONE": 5.134825334271083}
\ No newline at end of file
+{"null": 0.6604911223137445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6866.json
index 93beb9ff4da..5d2c62c7cc9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6866.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6866.json
@@ -1 +1 @@
-{"null": 1.6222395180044056}
\ No newline at end of file
+{"null": 1.4693700300919337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6867.json
index ef25f3c9b52..ef472bca7f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6867.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6867.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3252875190992175}
\ No newline at end of file
+{"COMIRNATY": 0.7802368621939515, "FENTANYL": 26.97953953146387, "null": 1.781399328295674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6868.json
index 4f6472f2d71..8308fea7121 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6868.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6868.json
@@ -1 +1 @@
-{"COMIRNATY": 1.227146762680521, "null": 1.1820190577204712}
\ No newline at end of file
+{"AFINITOR": 0.5583905739555742, "APROVEL": 2.3563820434167293, "BENLYSTA": 2.2067016550619942, "BRIDION": 6.82857273152593, "BRILIQUE": 1.460993872345053, "BUDESONIDE": 1.064386271026791, "CAELYX": 4.306993799886247, "CHAMPIX": 0.5312572089653312, "CINRYZE": 13.42755452938998, "CLOPIDOGREL": 0.3064621419888099, "COMIRNATY": 0.5139232268429279, "COSENTYX": 0.4342309804425032, "COTELLIC": 3.5443050167870074, "DARZALEX": 3.805211841234778, "DEXAMETHASONE": 0.667470363268846, "ENTRESTO": 1.2620027935884526, "EXFORGE": 1.8680002710767392, "FASENRA": 1.0737403063400213, "FENTANYL": 0.8201899980192657, "FORXIGA": 0.8353288307309965, "GARDASIL": 0.3329253721725629, "KEPPRA": 0.4190656087727259, "LANTUS": 0.2595411390750544, "LEVOFLOXACIN": 3.266547313750875, "MEKINIST": 0.7968821958676268, "MICARDIS": 2.215224960271684, "MIDAZOLAM": 1.8581586206540788, "NEXAVAR": 0.3288501907525329, "NUCALA": 0.931494487923058, "ONCASPAR": 10.590741067372392, "PLAVIX": 0.3394870801502215, "RELVAR": 3.2226990820626957, "RIXATHON": 17.021341113537023, "ROACTEMRA": 1.1549738882554332, "RUCONEST": 17.31579009665415, "SPIKEVAX": 0.1522903571840591, "SUTENT": 0.2643576333883023, "TOZINAMERAN": 0.2263430251779946, "VAXZEVRIA": 0.2796662253113549, "XARELTO": 1.5262617888824277, "XOLAIR": 3.921325090860384, "ZYPREXA": 0.4970998975757238, "null": 4.271362819499672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6869.json
index c7380a77665..730cc939e05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6869.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6869.json
@@ -1 +1 @@
-{"ADCIRCA": 7.579080276744194, "ALEMTUZUMAB": 6.253437234597988, "ANORO": 150.97359556812924, "APIXABAN": 25.446519638449697, "AZATHIOPRINE": 11.911018052991563, "BUSULFAN": 10.708045178031195, "CANCIDAS": 7.533468878919313, "CEFUROXIME": 50.65044261465893, "CELLCEPT": 3.9258014252236095, "CICLOSPORIN": 2.7187848792074947, "CLOPIDOGREL": 7.845440911121792, "CYTARABINE": 2.0754669119067217, "DEFITELIO": 106.68041045205912, "DEXAMETHASONE": 1.1954392223948425, "EFIENT": 61.38074092182914, "ELIQUIS": 7.392505885164575, "ENOXAPARIN": 5.429051976734282, "EPTIFIBATIDE": 105.89690505423144, "FENTANYL": 1.3053745219589692, "INTEGRILIN": 36.71392107007821, "IRESSA": 5.783167906744686, "JAKAVI": 2.9836123145226505, "LEMTRADA": 4.657545623267093, "LEVOFLOXACIN": 1.6076755954555573, "NEXAVAR": 1.004832794397346, "OPSUMIT": 3.155913088536193, "PLAVIX": 3.4027531918162035, "RITUXIMAB": 1.8802312959937848, "SOLIRIS": 1.751855212271492, "SPRYCEL": 2.164208839156093, "TAGRISSO": 4.041715289510191, "TICAGRELOR": 14.28467889812784, "TRACLEER": 1.5952230592904575, "XARELTO": 9.978223399768538}
\ No newline at end of file
+{"COMIRNATY": 0.6547990118425391, "GARDASIL": 12.417265225085814, "SPIKEVAX": 0.3154021209243218, "null": 2.247970677099546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/687.json
index a524395ecad..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/687.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/687.json
@@ -1 +1 @@
-{"JANUMET": 18.614370943470064, "ZOSTAVAX": 11.369181996580211, "null": 1.3338937209510662}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6870.json
index b2e7b6bb632..7b0694d35fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6870.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6870.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"CELECOXIB": 624.8137397924909}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6871.json
index c29a1a36adc..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6871.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6871.json
@@ -1 +1 @@
-{"ADCIRCA": 34.03274727586867, "ADEMPAS": 42.91335308582476, "AMBRISENTAN": 31.80249356509378, "APROVEL": 4.593692058006757, "BEDAQUILINE": 7.800259158453333, "BOSENTAN": 56.80937364260403, "BOSULIF": 15.220031608803955, "BOSUTINIB": 14.393438293893627, "BUSULFAN": 4.648918764940071, "CARFILZOMIB": 5.5852202288959525, "DACLATASVIR": 14.949931443156368, "DAKLINZA": 13.100647152090543, "ESBRIET": 2.014364389498221, "HARVONI": 2.038853115278949, "ICLUSIG": 2.6699524652904234, "ILOPROST": 133.50185266869389, "INSULIN": 2.667830054051859, "JAKAVI": 2.562257135838523, "KYPROLIS": 8.058510628485982, "LYRICA": 1.371359283541077, "MACITENTAN": 94.37490313307072, "NILOTINIB": 6.028320894887822, "NOXAFIL": 5.0337067460999245, "OFEV": 3.181696056288685, "OPSUMIT": 140.53341881036673, "PEGASYS": 1.2919086556317614, "PEGINTERFERON": 1.114550331864402, "REBETOL": 4.08549793623459, "REVATIO": 21.9022734796344, "RIBAVIRIN": 2.3689584657338605, "SILDENAFIL": 35.90049776212775, "SPRYCEL": 29.84099635259896, "TASIGNA": 1.169671982472085, "THIOTEPA": 17.042966491558634, "TRACLEER": 140.41012890439302, "UPTRAVI": 52.96220337989337}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6872.json
index 90867a72de2..1d708963e33 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6872.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6872.json
@@ -1 +1 @@
-{"IRBESARTAN": 167.3149328719622, "OPSUMIT": 43.99353773142183}
\ No newline at end of file
+{"BUDESONIDE": 509.07756759914537, "COMIRNATY": 0.1301959962942194, "null": 0.3787639307879772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6873.json
index ebd364b8732..23e3e05a71c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6873.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6873.json
@@ -1 +1 @@
-{"ENALAPRIL": 244.09730022711895, "OPSUMIT": 71.29521420598124, "REVATIO": 53.59038141320446, "SILDENAFIL": 50.3140559679749, "TRACLEER": 34.96529188329854, "null": 1.0156201345938076}
\ No newline at end of file
+{"null": 0.5450858387780103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6874.json
index 347a7f8f35d..2214c02aad1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6874.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6874.json
@@ -1 +1 @@
-{"OPSUMIT": 88.27062479916009, "null": 1.214010444928523}
\ No newline at end of file
+{"ABATACEPT": 1.4195989206241126, "ADALIMUMAB": 5.005343703164744, "AIMOVIG": 1.0072937006474063, "ARAVA": 2.9137068125697407, "BENLYSTA": 3.319218013145508, "BOTULINUM": 9.504592915624944, "CERTOLIZUMAB": 57.180123344778046, "CIMZIA": 0.5034627567776847, "COMIRNATY": 0.423999065325551, "COSENTYX": 3.969339775480597, "ELIQUIS": 0.5123378089973586, "GARDASIL": 0.8225340809054358, "HIZENTRA": 2.720504778039785, "HUMALOG": 0.5575176055142688, "IBRANCE": 1.9323572603687456, "LANTUS": 0.4705603938420968, "LEFLUNOMIDE": 12.469178823336575, "METHOTREXATE": 1.7262406798095644, "MMRVAXPRO": 3.3423246520516656, "OMALIZUMAB": 4.807693472849243, "OPSUMIT": 1.5195928478147924, "PEGASYS": 1.1762761845551106, "PEGINTRON": 1.268805367589687, "ROACTEMRA": 1.848796585782011, "SIMPONI": 2.314112735158809, "SPIKEVAX": 0.2314532276140981, "STELARA": 1.1467145908576488, "TOZINAMERAN": 0.6889052737780736, "TRELEGY": 2.5625749122838184, "VAXZEVRIA": 0.2632692979548949, "XELJANZ": 4.791922824414822, "XOLAIR": 2.761500365448212, "ZOSTAVAX": 0.7667854595775103, "null": 1.1785199886147495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6875.json
index 54e1db94d9f..d5a7b2652b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6875.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6875.json
@@ -1 +1 @@
-{"null": 2.3332252611448574}
\ No newline at end of file
+{"BUSULFAN": 102.72489640432362, "null": 1.1511229020506544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6876.json
index 491f14155be..4eae046db3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6876.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6876.json
@@ -1 +1 @@
-{"OPSUMIT": 34.98929783412678}
\ No newline at end of file
+{"THALIDOMIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6877.json
index c1ddd26a022..af3b7593ba8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6877.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6877.json
@@ -1 +1 @@
-{"null": 1.4824843710479705}
\ No newline at end of file
+{"DEXMEDETOMIDINE": 799.1178864668753, "null": 2.5796077606272654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6878.json
index d644269fde8..c36f0a81876 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6878.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6878.json
@@ -1 +1 @@
-{"null": 3.4845383477500658}
\ No newline at end of file
+{"null": 0.517280068315317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6879.json
index ebe50c549fd..0d49d3f7af6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6879.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6879.json
@@ -1 +1 @@
-{"null": 12.782248127989488}
\ No newline at end of file
+{"EXJADE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/688.json
index acb7768c253..20685963bd6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/688.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/688.json
@@ -1 +1 @@
-{"null": 2.039414910660589}
\ No newline at end of file
+{"ADALIMUMAB": 0.3423546595072538, "CELLCEPT": 1.84518300003838, "COMIRNATY": 0.0578614716100317, "ENTYVIO": 7.909111105889431, "INCIVO": 47.329415359232186, "JARDIANCE": 1.6914479067243378, "NEXAVAR": 1.2186480293969275, "PEGASYS": 37.35516016730588, "PEGINTERFERON": 30.33917692142135, "PEGINTRON": 3.7577784435142942, "RIBAVIRIN": 6.377334237445123, "SPIKEVAX": 0.1206105355375739, "SUTENT": 4.30887643639417, "VAXZEVRIA": 0.0957139884774363, "XELJANZ": 0.8137857168405568, "null": 1.4972493227685428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6880.json
index f3ce6617cb9..7ed0cafd3b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6880.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6880.json
@@ -1 +1 @@
-{"AVASTIN": 20.34702691297952, "BEVACIZUMAB": 26.998085716158297, "VAXZEVRIA": 1.1441133790889932}
\ No newline at end of file
+{"BRIDION": 87.22771154490684, "CAPECITABINE": 6.454868187428778, "COMIRNATY": 0.3786614107073693, "CYTARABINE": 2.435335974190288, "DEXAMETHASONE": 2.4977398764298027, "FASLODEX": 5.708060538392148, "FENTANYL": 11.343325950723226, "GLYCOPYRRONIUM": 19.779587415293364, "IRINOTECAN": 4.688715157889379, "MIDAZOLAM": 7.1455625288938265, "SUFENTANIL": 9.679819183490704, "TOZINAMERAN": 0.1944089138945429, "VAXZEVRIA": 0.0919703635770556, "XOLAIR": 1.6510515923117082, "null": 4.354952465309945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6881.json
index cbb4b87e1d0..1a94cc1e958 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6881.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6881.json
@@ -1 +1 @@
-{"AMIKACIN": 49.7260167254742, "STIVARGA": 14.51458307726868}
\ No newline at end of file
+{"null": 9.451381270346}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6882.json
index cf144338e1a..af09adb1db6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6882.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6882.json
@@ -1 +1 @@
-{"ABATACEPT": 1.3644606746938703, "ABILIFY": 1.958269989451284, "ADCIRCA": 6.701267320435047, "AFINITOR": 1.23813312061015, "ANORO": 2.914447132334597, "APIXABAN": 1.88847184260586, "ARAVA": 3.164545355822763, "AVANDIA": 1.878490921952356, "BENLYSTA": 1.3386764472235262, "BUMETANIDE": 30.546038460782796, "BUPRENORPHINE": 4.379786577794716, "DULOXETINE": 1.7097955689574895, "EMPAGLIFLOZIN": 8.528371870009366, "ENTRESTO": 4.078697337071549, "FASENRA": 1.954991391385687, "FENTANYL": 4.156492551291826, "IBUPROFEN": 1.0025722965301231, "INCRUSE": 10.464569005109356, "KYPROLIS": 4.6360577124864655, "MEPOLIZUMAB": 2.0375779091566675, "MULTAQ": 3.612147838508995, "NUCALA": 5.169707211856276, "OLANZAPINE": 6.12920825377303, "OMALIZUMAB": 2.3897913851600987, "OPSUMIT": 4.969111585035855, "PANTOPRAZOLE": 2.6408026265386635, "PEGINTRON": 1.3652034686346008, "REVATIO": 1.7516198164674233, "SPIRONOLACTONE": 5.505601221742188, "SPRYCEL": 2.0745240644969254, "SYNAGIS": 4.909881061699684, "TRACLEER": 3.4119826193508467, "TRELEGY": 12.505475988850742, "UMECLIDINIUM": 20.046673850321056, "VIAGRA": 1.2256975945676096, "XOLAIR": 6.035381876711719, "null": 1.5799245151352437}
\ No newline at end of file
+{"null": 5.195249144307421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6883.json
index 9fe339f1f00..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6883.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6883.json
@@ -1 +1 @@
-{"null": 1.119506281660774}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6884.json
index d11249077c2..2f97c65a06e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6884.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6884.json
@@ -1 +1 @@
-{"ABRAXANE": 1.9152568636123255, "ACTRAPID": 1.255880945651109, "ADVAGRAF": 1.5140691562570203, "ALIMTA": 1.690354492209511, "ANAKINRA": 5.026160884739034, "ANORO": 7.345504148702695, "APIXABAN": 2.0682946432637017, "ARIXTRA": 3.0498742035085766, "ASPARAGINASE": 1.0610555642709398, "AVASTIN": 4.438492024092371, "AVELUMAB": 1.5745595700834036, "AXITINIB": 1.2152913589849417, "BEDAQUILINE": 2.4872482502574926, "BEVACIZUMAB": 2.522776190224362, "BINOCRIT": 2.3926110737733217, "CABAZITAXEL": 1.8387960980721136, "CABOMETYX": 2.137290749964777, "CAELYX": 1.18435387453234, "CANAGLIFLOZIN": 2.424857553112984, "CAPECITABINE": 1.0146344108654557, "CARFILZOMIB": 1.9548962428155263, "CARMUSTINE": 1.1584125920024886, "CINACALCET": 1.80853677053114, "CINRYZE": 1.5897671484059384, "COMIRNATY": 1.2722827587901848, "COVID19": 1.5513964965427989, "DELAMANID": 1.7047877093558876, "DEXAMETHASONE": 1.3270438534387936, "EBIXA": 5.497713825080997, "ELIQUIS": 5.046316190752374, "EMEND": 1.076128314919092, "ENOXAPARIN": 4.808955317205691, "ERBITUX": 1.0156473165691589, "ERLOTINIB": 19.003612206779547, "ESBRIET": 1.3240651164815456, "ESMYA": 2.250017182493361, "EVENITY": 1.0197002206253825, "EVISTA": 17.91445464567648, "EVRA": 8.964385213582462, "FASLODEX": 2.0974131499327986, "FLEBOGAMMA": 1.4084380627533055, "FULVESTRANT": 1.172434005325155, "GONALF": 1.051716114889797, "HALAVEN": 1.1988750470620173, "HIZENTRA": 1.4374583747091112, "HUMAN": 2.998688500984221, "IBRANCE": 1.2107337619584662, "INFLIXIMAB": 1.4636077297079793, "INHIXA": 5.448588220112636, "INTEGRILIN": 1.100476781650277, "INVEGA": 1.2643968600263802, "IRESSA": 1.0561625766092966, "IRINOTECAN": 1.2883792238230314, "JAKAVI": 1.1061648512657714, "JEVTANA": 1.0681628109259549, "KIOVIG": 1.464698132478759, "KYPROLIS": 1.8666720891376805, "LENVIMA": 1.528341634415047, "LIXIANA": 2.609819612221366, "LOXAPINE": 2.5113314247839105, "LYNPARZA": 1.057051517316805, "MEKINIST": 1.567894976646821, "MVASI": 2.0226646515951123, "NOVOSEVEN": 16.17265945187263, "NPLATE": 3.889300773120176, "OFEV": 1.9471853272808, "OLANZAPINE": 2.3233143192781363, "OLAPARIB": 1.4986740171678048, "ONCASPAR": 1.5839038833151504, "OSIMERTINIB": 4.272548256537188, "PACLITAXEL": 1.1325488683112954, "PEGFILGRASTIM": 3.4296730116728518, "PEMETREXED": 1.2775886917135924, "POMALIDOMIDE": 2.657763824979871, "PRAXBIND": 3.630379172301986, "PRIVIGEN": 2.0149134485371296, "PROTELOS": 14.161009928520787, "REVLIMID": 1.6108387173302432, "RINVOQ": 7.159614062367764, "RIVAROXABAN": 4.852968068291953, "RIXATHON": 1.0356285152125688, "ROACTEMRA": 1.750137819649089, "SKYRIZI": 1.4307224899256652, "SOLIRIS": 1.0902776801497316, "SOMAVERT": 5.5440660845432586, "STELARA": 1.2750852856546908, "TAGRISSO": 3.061761150380486, "TEMODAL": 3.8037498622127535, "TEMOZOLOMIDE": 1.7973037201836353, "TESTOSTERONE": 8.985918267734501, "THALIDOMIDE": 8.641650065482954, "TOCILIZUMAB": 1.1882857069970263, "TOFACITINIB": 5.458139007201937, "TORISEL": 1.0841098398776166, "UPADACITINIB": 5.712447604030968, "VAXZEVRIA": 1.4595842554948968, "VECTIBIX": 1.252736268119898, "VOTRIENT": 1.0622566974403571, "XALKORI": 3.251779859054128, "XARELTO": 4.876961422887843, "XELJANZ": 1.888109935514508, "XOLAIR": 1.2729682122357848, "YONDELIS": 2.0523336845785307, "ZYPREXA": 2.1530327472684765}
\ No newline at end of file
+{"COMIRNATY": 1.6566212174240087, "SPIKEVAX": 0.3807397009926788, "null": 2.022440413213632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6885.json
index 88103a01fb6..f7d35e4a258 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6885.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6885.json
@@ -1 +1 @@
-{"OPSUMIT": 300.32451154033663}
\ No newline at end of file
+{"null": 0.9451536364128428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6886.json
index 15906f71796..82b932639e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6886.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6886.json
@@ -1 +1 @@
-{"CUBICIN": 497.9393578332279, "MEPOLIZUMAB": 19.24550781904297, "null": 2.4158785589986813}
\ No newline at end of file
+{"JARDIANCE": 22.34551611401069, "TOZINAMERAN": 2.3771964655128923, "null": 0.1665579755547573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6887.json
index 245f53db122..0f5524f117e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6887.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6887.json
@@ -1 +1 @@
-{"ABATACEPT": 2.4159939921091484, "ADALIMUMAB": 5.0953882977752825, "AFINITOR": 1.316576201636093, "ALIMTA": 2.1651331781184164, "AMINOSALICYLIC": 1.0862832304163204, "ANAKINRA": 8.087008746306887, "ANORO": 46.04900511815978, "APIXABAN": 7.385625998221702, "ARAVA": 2.688814806170543, "AVASTIN": 1.0466337582022305, "AZATHIOPRINE": 4.399167356291366, "BUDESONIDE": 6.52703828822927, "CELLCEPT": 3.012345155079541, "CHLORMETHINE": 31.862610923958854, "CIALIS": 4.237300140028569, "CIMZIA": 1.350333160490703, "DOCETAXEL": 1.3195806474840774, "DOXORUBICIN": 1.8817513244626016, "ENBREL": 3.02088802227466, "ESBRIET": 10.172533765134656, "EXFORGE": 1.139907773183974, "FASENRA": 1.2776042184744918, "FIRDAPSE": 3.287769988996234, "FORSTEO": 1.1965344994266265, "GLIVEC": 2.498061624517764, "HERCEPTIN": 2.1951484717100342, "HUMIRA": 1.1775033769345369, "INCIVO": 1.330073280636188, "IRESSA": 2.571176689742857, "JANUMET": 1.163226716858712, "JANUVIA": 1.379617198195246, "LEFLUNOMIDE": 2.842033001405201, "LYRICA": 1.3852772596808358, "MABTHERA": 5.333651518425477, "METHOTREXATE": 2.631852726935992, "MICARDIS": 1.6791455110865692, "MULTAQ": 8.012815510561927, "NEULASTA": 1.900360934545795, "NUCALA": 1.885888825184345, "OFEV": 10.79908655657334, "OPSUMIT": 1.7439421950258904, "OPTIMARK": 1.53010535377926, "PANTOPRAZOLE": 1.3201553848519725, "PEGASYS": 1.190182422224959, "PEGINTERFERON": 1.679637935980256, "PEGINTRON": 1.4562645637864708, "PEMBROLIZUMAB": 2.3439105708916537, "RAPAMUNE": 5.7107614439992185, "REVATIO": 6.60847289045028, "RITUXIMAB": 1.8081151918419, "ROACTEMRA": 2.313871643786244, "SIMPONI": 1.0332699616420231, "TAGRISSO": 1.440647758918172, "TORISEL": 3.1487357653292696, "TRACLEER": 5.972027503145929, "TRELEGY": 2.3508006099854293, "XELJANZ": 2.2105525860488893, "null": 1.6064801856355622}
\ No newline at end of file
+{"BUDESONIDE": 3.770646804460164, "CIMZIA": 9.261473185615198, "COSENTYX": 5.612490553532576, "ENBREL": 17.4789889343654, "IBUPROFEN": 13.111466005016824, "INFLIXIMAB": 38.66918822824572, "METHOTREXATE": 8.982189379317047, "SIMPONI": 9.897086756637323, "STELARA": 46.130711852183005, "TREMFYA": 22.444994688216635, "XELJANZ": 4.353127593578907, "null": 0.1994184402851835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6888.json
index 4aa97eedb18..89d83c8033d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6888.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6888.json
@@ -1 +1 @@
-{"ALENDRONATE": 555.3912433028696, "APIXABAN": 24.79396357922719, "AVAMYS": 21.718539437471865, "BUDESONIDE": 115.08364956321054, "ELIQUIS": 1.1465396571915676, "ENTRESTO": 5.357829792949751, "ESBRIET": 34.56912328079721, "MEPOLIZUMAB": 10.90099661436422, "NUCALA": 119.7356182793479}
\ No newline at end of file
+{"COMIRNATY": 0.7384400662348386, "VAXZEVRIA": 0.8539773199385199, "null": 0.6104396912921957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6889.json
index 6ad845a9d0a..583196c8637 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6889.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6889.json
@@ -1 +1 @@
-{"BUDESONIDE": 1.6519469280665986, "CELLCEPT": 1.8170370272068743, "CICLOSPORIN": 1.978053920171596, "ESBRIET": 29.52444949458685, "FASENRA": 21.748748197553148, "FENTANYL": 1.7953228200733926, "KAFTRIO": 28.03284423729225, "KALYDECO": 190.13814207809693, "NUCALA": 5.468197097036077, "OFEV": 16.866008493366138, "OMALIZUMAB": 7.83653574971045, "ORKAMBI": 366.0563109608832, "PIRFENIDONE": 46.75724283173488, "TOBI": 166.51235418965229, "TRELEGY": 5.028492387276258, "XOLAIR": 11.295100128559682, "null": 1.2118058288524698}
\ No newline at end of file
+{"PRIVIGEN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/689.json
index 1adb98a106e..0f7e8c72125 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/689.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/689.json
@@ -1 +1 @@
-{"null": 1.027644819758759}
\ No newline at end of file
+{"ADALIMUMAB": 0.6757954386378301, "COMIRNATY": 0.1304483515310478, "ENTYVIO": 12.496014678411148, "INCIVO": 69.15428657856077, "PEGASYS": 5.565616156234569, "PEGINTERFERON": 8.284601741361508, "RIBAVIRIN": 9.232428133105154, "STELARA": 2.9031116888972464, "SUTENT": 5.018092754543758, "XELJANZ": 2.310886177790797, "null": 1.3096654584598082}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6890.json
index 0b422a5642d..bc6127e4081 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6890.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6890.json
@@ -1 +1 @@
-{"IRBESARTAN": 33.05367305716744, "JANUMET": 11.62897203542033, "PEGASYS": 2.546950649512058}
\ No newline at end of file
+{"COMIRNATY": 0.2110000531903133, "CYMBALTA": 3.049062261004409, "LANTUS": 8.266097074802442, "null": 0.9927135276884356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6891.json
index 2f283a89478..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6891.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6891.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 45.76330366533475, "null": 1.0124475158719186}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6892.json
index d907b18635e..4d7fd3e43de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6892.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6892.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 9.235347963653105, "AMIKACIN": 11.089191250638232, "AMINOSALICYLIC": 1.692571061133446, "ANGIOX": 62.2819798164794, "ASPARAGINASE": 6.85738638256523, "AVASTIN": 2.3209362428387066, "BEDAQUILINE": 5.979520117147652, "BRILIQUE": 8.164215568312883, "BRIVARACETAM": 17.43455959639538, "BUSULFAN": 10.549305345227154, "CELLCEPT": 1.817885899560673, "CICLOSPORIN": 2.91993146703286, "CLOPIDOGREL": 8.600919746395673, "CYTARABINE": 5.385205252880625, "DEFITELIO": 87.19483393321273, "DEXAMETHASONE": 5.065146352759211, "ELIQUIS": 5.989129532778697, "ENOXAPARIN": 5.891293067287945, "FEBUXOSTAT": 15.529225430457023, "FENTANYL": 2.599983557758034, "INTEGRILIN": 40.508386290727714, "JAKAVI": 1.9524124576435904, "KAFTRIO": 7.2790766469358115, "KEYTRUDA": 1.0828432971917965, "NOVOSEVEN": 16.943045039242946, "NPLATE": 4.167726210467282, "OPSUMIT": 2.559152180019192, "PLAVIX": 5.6282966646416615, "RAPAMUNE": 7.003058264287289, "REVATIO": 2.8356317966961444, "SOLIRIS": 6.182812603604899, "SUTENT": 1.768371777375218, "TICAGRELOR": 14.73140373657302, "TRACLEER": 5.261708859275798, "VFEND": 3.072916918495556, "VOTRIENT": 2.8514412085888394, "XARELTO": 8.910864175538967, "null": 1.1232544450425828}
\ No newline at end of file
+{"BUPRENORPHINE": 91.4968579963664, "FENTANYL": 14.239131217204893, "GARDASIL": 2.624044532511292, "KEPPRA": 4.171553984312315, "SUBOXONE": 17.15947908300515, "null": 4.460039952050711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6893.json
index 612fe7b5f21..c2331b4a666 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6893.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6893.json
@@ -1 +1 @@
-{"null": 4.047972505381089}
\ No newline at end of file
+{"COMIRNATY": 0.0481899203217531, "GARDASIL": 2.857511896507905, "KEPPRA": 4.947357626438703, "null": 10.04145857626054}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6894.json
index a7d1cb66028..2cfe8f7ece8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6894.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6894.json
@@ -1 +1 @@
-{"ADCIRCA": 17.367461238321393, "ADEMPAS": 15.367376900273689, "AMBRISENTAN": 23.393007946377143, "ANAKINRA": 1.3354434848071806, "AVANDAMET": 4.95285884304413, "AVANDIA": 7.998518804061009, "BEDAQUILINE": 2.5720151919328944, "BORTEZOMIB": 2.7486597628446803, "BOSENTAN": 35.76278630176294, "BOSULIF": 10.091001338829225, "BOSUTINIB": 11.502867731194586, "BUMETANIDE": 3.4243357696157606, "BUSULFAN": 6.157160189285119, "CARFILZOMIB": 7.912097822110903, "CELLCEPT": 1.432528119280125, "CUBICIN": 1.4543443655089496, "DAPAGLIFLOZIN": 4.894571905108378, "DASATINIB": 19.216775396516987, "ELIQUIS": 1.0272547945830783, "ENTRESTO": 3.667162414004477, "EPIVIR": 3.183165601144518, "ESBRIET": 4.035586343209769, "ESOMEPRAZOLE": 2.539047318102392, "EXJADE": 2.266171219091458, "GANCICLOVIR": 2.3506556572309822, "GLIVEC": 3.956278344060807, "HERCEPTIN": 1.596354844335064, "ICLUSIG": 4.181125461880895, "INVIRASE": 6.968597543299654, "IRON": 3.7427021417020616, "JAKAVI": 5.022630295535064, "KYPROLIS": 26.788262446063747, "LIXIANA": 1.8156546928390864, "MACITENTAN": 34.310280620018325, "MELPHALAN": 6.042918517704777, "MICARDIS": 1.384701836561718, "MULTAQ": 1.632452442966656, "NAGLAZYME": 12.240760215941242, "NILOTINIB": 6.39518956726823, "NPLATE": 1.350914159559944, "OFEV": 8.38786401808802, "OPSUMIT": 31.738627186307436, "PEGINTRON": 1.1783950330434692, "REBETOL": 2.5768268485475616, "REVATIO": 100.21136138757144, "RIOCIGUAT": 102.00807033669888, "SILDENAFIL": 25.67079141601149, "SOLIRIS": 1.7863842773278815, "SPRYCEL": 36.73884058237484, "SYNAGIS": 5.552956579381494, "TAGRISSO": 1.0543888352114748, "TASIGNA": 2.275815826709607, "THALIDOMIDE": 2.786863653378804, "TOBRAMYCIN": 4.374604381434981, "TRACLEER": 49.42326982649671, "TRACTOCILE": 24.30728274357121, "VIAGRA": 4.155967594779621, "ZOSTAVAX": 1.1216891605062589}
\ No newline at end of file
+{"APIXABAN": 6.356112310848366, "ARIPIPRAZOLE": 70.75078398482489, "BUMETANIDE": 462.6818693399988, "COMIRNATY": 0.100607106144525, "EMPAGLIFLOZIN": 159.2949034589921, "ENTRESTO": 13.847323651152758, "null": 0.6531172894003452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6895.json
index d93ec930069..40778e0b3db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6895.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6895.json
@@ -1 +1 @@
-{"MIDAZOLAM": 82.23507540598621, "SILDENAFIL": 154.89982622942753, "TRACLEER": 157.9687662366876}
\ No newline at end of file
+{"AVANDIA": 11.297753703386013, "COMIRNATY": 0.1858631725394315, "ENTRESTO": 30.113201636170395, "SPIKEVAX": 0.2344075825887756, "null": 1.4111802266180398}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6896.json
index a597a1a83aa..14b9fca22ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6896.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6896.json
@@ -1 +1 @@
-{"MICARDIS": 33.60099092924455, "null": 3.362580272432991}
\ No newline at end of file
+{"null": 0.7437140097535307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6897.json
index c30e054bafe..f232e941921 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6897.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6897.json
@@ -1 +1 @@
-{"ACTRAPID": 53.37005354475439, "COMIRNATY": 1.3734362164873166, "ELIQUIS": 1.2627029744659517, "SPIKEVAX": 1.027389367844578, "VAXZEVRIA": 1.2340059653759772, "ZYPREXA": 2.2766425526113023}
\ No newline at end of file
+{"null": 3.856909114057416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6898.json
index 18f6ae34ea8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6898.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6898.json
@@ -1 +1 @@
-{"null": 3.891465979519322}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6899.json
index d06c47f2503..b2b93ec3916 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6899.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6899.json
@@ -1 +1 @@
-{"null": 4.064830965845844}
\ No newline at end of file
+{"BUMETANIDE": 312.61300321709945, "COMIRNATY": 0.1184911680236554, "ENTRESTO": 26.345040155626634, "IRBESARTAN": 32.987062152563816, "null": 1.283770577906473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/69.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/69.json
index 738281c8d97..d43dc6d16fd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/69.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/69.json
@@ -1 +1 @@
-{"null": 1.756196526127696}
\ No newline at end of file
+{"null": 2.655635127655816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/690.json
index a4b83dd43ea..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/690.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/690.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.4906567939184865, "ABRAXANE": 10.14915246132696, "ACLIDINIUM": 1.7582497135720154, "ADCIRCA": 8.199063021325125, "ADEMPAS": 2.994572045662028, "ADENURIC": 2.188161820677574, "AFINITOR": 5.301498375640612, "ALEMTUZUMAB": 1.819209621268613, "ALIMTA": 1.3273225370098023, "AMBRISENTAN": 3.427845662302708, "AMINOSALICYLIC": 1.250189514981529, "ARANESP": 43.55920766000221, "ASPARAGINASE": 2.9117593433638747, "AVANDIA": 1.2860679964480726, "AVASTIN": 3.7675203174012375, "AZATHIOPRINE": 1.4202217743612096, "BARACLUDE": 6.507745034903077, "BASILIXIMAB": 2.88510586472433, "BEDAQUILINE": 2.4510172527365754, "BEMFOLA": 161.00914269102768, "BEVACIZUMAB": 4.268068885608932, "BOCEPREVIR": 9.402611649064644, "BORTEZOMIB": 3.767389091003765, "BRAFTOVI": 1.3861775378904917, "BUSULFAN": 3.594930684798791, "BYETTA": 5.16060959947885, "CABOMETYX": 3.794491057270093, "CAELYX": 4.495874422105774, "CAPECITABINE": 3.8488747112519217, "CARFILZOMIB": 2.231609080132509, "CELLCEPT": 2.31299651160958, "CETROTIDE": 89.61599178002868, "CICLOSPORIN": 2.0196798875121744, "COMBIVIR": 2.9933114466888284, "CRIXIVAN": 1.7315016646412813, "CYTARABINE": 2.2716440856686604, "DACLATASVIR": 15.145343648683788, "DAKLINZA": 4.298027711624499, "DARBEPOETIN": 45.03706912035207, "DARUNAVIR": 3.265958140037682, "DEFITELIO": 8.375447960336, "DOCETAXEL": 1.3953985988882625, "EMTRICITABINE": 2.9907718284534512, "ENTRESTO": 1.6895710685217418, "ENVARSUS": 22.175002988121147, "EPCLUSA": 13.8641180105857, "EPIVIR": 2.423103024940346, "EVEROLIMUS": 2.765764743568304, "EXJADE": 1.7475585659519826, "EXVIERA": 38.64683858815975, "FASLODEX": 3.364705001114162, "FLUTICASONE": 10.217987173605913, "FOLLITROPIN": 20.367545688404647, "FULVESTRANT": 2.5619762736121907, "GANCICLOVIR": 1.970222675013314, "GLIVEC": 3.7386500859838, "GONALF": 106.8557568777973, "HALAVEN": 1.490877899091061, "HARVONI": 15.005517187332382, "HEPSERA": 2.3581492124856798, "HERCEPTIN": 1.574622375685576, "IBRANCE": 1.912471635411611, "INCIVO": 6.281502988457305, "INFLIXIMAB": 1.3735550545495392, "INLYTA": 1.2428404524098566, "INSULIN": 1.077078962722326, "INTRONA": 5.518125061279705, "IRINOTECAN": 2.861341402460185, "ISENTRESS": 3.734869467185293, "JAKAVI": 4.266644126197976, "JANUMET": 2.008981467513166, "JANUVIA": 2.9548622956717066, "JEVTANA": 1.1873116707185498, "KALETRA": 1.9992829722730523, "KEYTRUDA": 2.281882678551992, "KISQALI": 1.3146302690575022, "LAMIVUDINE": 3.254510077463169, "LENVIMA": 11.947432428003705, "LONSURF": 6.352302478703547, "LUTATHERA": 5.0770647999392216, "LUVERIS": 23.48742004773497, "LYNPARZA": 3.7112777515745257, "MABTHERA": 1.4683384331893126, "MACITENTAN": 5.7853181420963065, "MELATONIN": 2.2058623239586965, "MELPHALAN": 3.146105082320292, "MIDOSTAURIN": 12.16445840759628, "NEXAVAR": 14.769718058471272, "NPLATE": 1.828969276955752, "OCALIVA": 15.496527183662744, "OLYSIO": 11.281419352584866, "ONCASPAR": 4.633524375200259, "OPDIVO": 1.2177713568640771, "OPSUMIT": 4.271538195890879, "ORGALUTRAN": 102.59086172730392, "OVITRELLE": 133.2724701498231, "PACLITAXEL": 2.0264143546980544, "PAZOPANIB": 2.204751588921844, "PEGASYS": 4.447282353762029, "PEGINTERFERON": 3.7841851538138807, "PEGINTRON": 3.2844314620525217, "PEMBROLIZUMAB": 1.5845388718284616, "PEMETREXED": 1.1016005954653318, "PUREGON": 12.860592918138916, "RAPAMUNE": 2.000256793249996, "REBETOL": 6.4896854900750505, "REVATIO": 2.539587105426261, "RIBAVIRIN": 8.615231177692301, "RUBRACA": 4.4295438950554695, "SILDENAFIL": 2.159338827572346, "SIMEPREVIR": 7.538686831364737, "SOFOSBUVIR": 5.870984986841708, "SOLIRIS": 2.3419238942317158, "SORAFENIB": 5.550053398271658, "SOVALDI": 9.094616982559542, "SPIRONOLACTONE": 2.1136240177036707, "SPRYCEL": 2.692870506318313, "STIVARGA": 7.269938269043571, "SUTENT": 4.018100715684891, "TASIGNA": 1.0907422556454291, "TORISEL": 3.935584745180045, "TRACLEER": 5.747668120628645, "TRODELVY": 1.6989136810832492, "VIRAMUNE": 6.555868611360491, "VOTRIENT": 1.801816983628868, "XALKORI": 1.132337885771065, "XELODA": 1.2982650080741345, "YERVOY": 1.180958496205376, "ZEPATIER": 5.837390909391751}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6900.json
index 66e7a1ad4d5..ff8c596a8a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6900.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6900.json
@@ -1 +1 @@
-{"ABRAXANE": 23.2670822950978, "ACLIDINIUM": 9.542625971180897, "AFINITOR": 5.010748721030412, "ALIMTA": 1.3961495722791586, "AMIKACIN": 5.923889203078185, "ANORO": 2.2731693711920737, "ARAVA": 2.4991775845595097, "AVAMYS": 7.133560864907831, "AVASTIN": 1.7885541940272467, "AXITINIB": 3.930864957697491, "AZATHIOPRINE": 3.3309915556307703, "BENLYSTA": 1.044126969354095, "BENRALIZUMAB": 6.782565840003742, "BEVACIZUMAB": 1.5376870397174212, "BUDESONIDE": 8.883982298328002, "BUPRENORPHINE": 1.656718254207495, "BYETTA": 7.945015212628883, "CABOMETYX": 2.6558922215860323, "CAPECITABINE": 4.236376950585338, "CASPOFUNGIN": 6.206885209668884, "CICLOSPORIN": 3.1334319840368265, "CIMZIA": 1.324727139164747, "CLOFARABINE": 15.478337669749374, "COSENTYX": 1.1955207950244324, "CYTARABINE": 3.13730654094062, "DABRAFENIB": 6.528449299665128, "DEXAMETHASONE": 1.236945624852458, "DOCETAXEL": 2.9186407385575883, "DULOXETINE": 4.305625990809034, "ENBREL": 2.178794883435444, "ENTYVIO": 1.3332082064258617, "FASENRA": 2.1948267348719708, "FASLODEX": 2.840537043293524, "FIRDAPSE": 7.148871893842365, "FULVESTRANT": 5.03761006940257, "GEFITINIB": 6.943093835059006, "GLYCOPYRRONIUM": 16.43957354278706, "HUMIRA": 1.3839191321102688, "IBRANCE": 2.1814186579031767, "IBUPROFEN": 1.542605745605217, "INLYTA": 1.2321627488494633, "INSULIN": 2.9107527809805624, "IPILIMUMAB": 2.518144752577629, "IRESSA": 3.188748393657633, "IRINOTECAN": 3.750846947698205, "JAKAVI": 2.019512198295076, "JANUMET": 8.060156554004632, "JANUVIA": 6.848373101185476, "KEYTRUDA": 1.6663866283213626, "KISQALI": 2.3870699690185435, "MEKINIST": 2.8087882270481943, "MEPOLIZUMAB": 9.745079026609538, "METHOTREXATE": 1.9068547003603649, "MYCOPHENOLATE": 3.2598455729153497, "NEULASTA": 1.6915696385935175, "NEXAVAR": 2.852158342263045, "NOXAFIL": 4.456824297816995, "NUCALA": 6.692055826789549, "PAZOPANIB": 4.235672980853655, "PEGASYS": 1.2746266526790728, "PEMBROLIZUMAB": 1.7403233392645427, "RIBOCICLIB": 5.1817882879946335, "RINVOQ": 1.0190070162214862, "RITUXIMAB": 1.2835069946173905, "SIMPONI": 1.5188125505632497, "STELARA": 1.363641175830183, "STIVARGA": 2.998664571389495, "SUTENT": 1.6488766866073217, "TAGRISSO": 2.911086503171793, "TRELEGY": 6.805215879296961, "VORICONAZOLE": 4.282430518265219, "VOTRIENT": 4.092971664586369, "XELJANZ": 2.1888785552435923, "XOLAIR": 3.007078089172426, "ZOSTAVAX": 3.502448876018047}
\ No newline at end of file
+{"ABILIFY": 5.327319686394221, "ALIMTA": 2.708297761606201, "ARIPIPRAZOLE": 16.87092705486774, "AVANDAMET": 5.097039210258387, "AVANDIA": 6.683133943722663, "AVASTIN": 3.703448119448539, "BEVACIZUMAB": 6.37340064366202, "BRILIQUE": 2.258423760132573, "CAPECITABINE": 5.862944420941027, "CELLCEPT": 2.1271351444304787, "CICLOSPORIN": 1.337097683260298, "CLOPIDOGREL": 4.390948674428052, "COMIRNATY": 0.232888977522153, "CYTARABINE": 1.8835761924312624, "DOCETAXEL": 12.841853667874345, "DOXORUBICIN": 3.170162348835011, "EDOXABAN": 68.17938670480908, "ENTRESTO": 16.764707657584573, "FENTANYL": 1.5393491093736569, "GEFITINIB": 13.46179432791123, "HERCEPTIN": 15.078983352772816, "KYMRIAH": 6.337394284218184, "KYPROLIS": 6.130115922622025, "MEKINIST": 2.191451720599213, "MIDAZOLAM": 8.197069944707433, "NEXAVAR": 1.929065321048978, "OLANZAPINE": 1.3707830148669988, "PERTUZUMAB": 37.70973436625419, "RITUXIMAB": 1.8735156008263227, "SPIKEVAX": 0.1973593977502318, "SPIRONOLACTONE": 7.437639440475072, "STIVARGA": 1.4858772384252443, "SUTENT": 1.0670567175901085, "TASIGNA": 2.6676142016898914, "TOZINAMERAN": 0.4468755879418016, "VALSARTAN": 8.835973442662553, "VAXZEVRIA": 0.1049004719294279, "VOTRIENT": 3.168735737032114, "ZOSTAVAX": 0.6740204490108815, "null": 1.1378486617918555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6901.json
index 74de6f006ac..bf0c9320dda 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6901.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6901.json
@@ -1 +1 @@
-{"null": 2.807860034721575}
\ No newline at end of file
+{"null": 1.4168104851537229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6902.json
index 112450b3a5d..8f5f80b5cb6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6902.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6902.json
@@ -1 +1 @@
-{"MYCOPHENOLATE": 94.65333735805204, "VORICONAZOLE": 127.70810980739692}
\ No newline at end of file
+{"COMIRNATY": 0.176218334400711, "ENTRESTO": 67.98384027123443, "null": 1.0902528833889469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6903.json
index 4e14087e16c..bb368856b30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6903.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6903.json
@@ -1 +1 @@
-{"FASENRA": 152.91542792823836}
\ No newline at end of file
+{"ADCIRCA": 14.08996904100706, "AVANDIA": 6.345851504312924, "BUSULFAN": 5.95183012182659, "COMIRNATY": 0.3313296571124877, "DASATINIB": 26.891434496853503, "ELIQUIS": 1.6909692923119612, "ENTRESTO": 3.863290671981001, "MULTAQ": 10.09203072065948, "NEXAVAR": 1.1880630161458223, "ONGLYZA": 70.64423012632452, "OPSUMIT": 12.50250145772203, "REVATIO": 10.348056324913514, "SPIKEVAX": 0.2164943539481531, "SUTENT": 1.7851592864868666, "TOZINAMERAN": 0.2071897109325691, "TRACLEER": 10.338111683798267, "VAXZEVRIA": 0.1055334544645605, "ZOSTAVAX": 1.271373199837596, "null": 1.50312039968343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6904.json
index c075bade599..49e1fab8d92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6904.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6904.json
@@ -1 +1 @@
-{"ACTOS": 5.180907871814076, "ADCIRCA": 8.875696350087567, "ADEMPAS": 2.947910859645714, "AFINITOR": 1.217530800814558, "ALIMTA": 1.0030446061043805, "AMBRISENTAN": 2.9655075655627914, "AMIKACIN": 1.1822827709549988, "ASENAPINE": 24.880606769870635, "ATOSIBAN": 4.59165045405609, "AVAMYS": 1.4907696550623677, "AVANDAMET": 7.574492324585017, "AVANDIA": 10.488578994774208, "BEDAQUILINE": 2.3006129409785987, "BORTEZOMIB": 4.261555161053419, "BOSENTAN": 8.245813560887624, "BOSULIF": 10.766213735254556, "BRIDION": 8.729463476304744, "BRILIQUE": 1.5754340097281352, "BUMETANIDE": 1.9542445801102757, "BUPIVACAINE": 1.10284330799705, "BUPRENORPHINE": 3.3249581535122426, "BUSULFAN": 1.0511551887272252, "CARFILZOMIB": 3.3749397771239984, "CELLCEPT": 1.2940460532528737, "CLOPIDOGREL": 1.248302400200259, "CYTARABINE": 1.6031908153942604, "DAPAGLIFLOZIN": 7.93526264441068, "DARZALEX": 1.523875998122513, "DEXAMETHASONE": 1.9193140269508613, "DULOXETINE": 1.828347222886375, "ELIQUIS": 1.560490833211455, "ENOXAPARIN": 1.058261520267953, "ENTRESTO": 3.815517905871005, "EPIVIR": 1.1781507785179657, "ESBRIET": 2.9314609956326847, "ESOMEPRAZOLE": 1.7320209968271971, "EXFORGE": 1.5863583636908938, "EXJADE": 1.0187878897858618, "FENTANYL": 6.271926207127636, "FIRDAPSE": 1.916116538786418, "FORSTEO": 1.826762238033652, "GALVUS": 2.320313057417405, "GLIVEC": 1.269867042257236, "GLUCAGON": 3.5913178479123147, "HERCEPTIN": 1.6138408480081936, "HUMALOG": 2.6133288243702224, "HUMAN": 1.3208726893845275, "IBRANCE": 3.798827063230996, "ICLUSIG": 1.6132103214556532, "INLYTA": 2.052953699506774, "INSULIN": 1.254567018649269, "INTEGRILIN": 5.1737116660134, "IRESSA": 1.5966236877569544, "IVABRADINE": 33.54157949263872, "KALETRA": 1.571307443383492, "KYMRIAH": 1.634416972121017, "KYPROLIS": 7.658450059119675, "MACITENTAN": 11.238829984801614, "MEKINIST": 1.1175102856378685, "MIDAZOLAM": 2.899821349568149, "MIMPARA": 1.2375222141765705, "MIRCERA": 2.24889442074537, "MULTAQ": 3.857883659075641, "NAGLAZYME": 2.429946561172671, "NALOXONE": 8.185749641004541, "NOVOSEVEN": 2.615455282803346, "OLANZAPINE": 1.325227499906859, "OLYSIO": 1.035395017477644, "OPSUMIT": 7.698999011975298, "PRIVIGEN": 1.583553536383536, "RAPAMUNE": 1.857044433138602, "RASILEZ": 2.350026519253161, "RELVAR": 1.1575107530661826, "REVATIO": 5.422430920585623, "REVLIMID": 1.21152385180053, "SILDENAFIL": 5.90920893639601, "SOLIRIS": 2.0590294775563405, "SPIRONOLACTONE": 2.293647973691361, "SPRYCEL": 35.82384011054767, "SUTENT": 2.3141985602382054, "TAGRISSO": 2.745842825195677, "TASIGNA": 2.149676524855153, "TORISEL": 2.302689229827512, "TRACLEER": 5.329283667921053, "TRACTOCILE": 44.54722180397435, "TRELEGY": 2.6999500823917546, "VALSARTAN": 2.102944257608985, "VELTASSA": 4.81279038444067, "VFEND": 1.11170290420613, "VIRAMUNE": 2.8204866214109217, "VOTRIENT": 1.2760501546530911, "XALKORI": 4.487951841546872, "ZYPREXA": 1.0263082734882374, "null": 1.566990406458451}
\ No newline at end of file
+{"ACTOS": 14.489749653736553, "AMINOSALICYLIC": 2.828867267371061, "AVANDIA": 7.09938559562857, "AZATHIOPRINE": 3.479438348075796, "BEDAQUILINE": 5.751340668676269, "CLOPIDOGREL": 2.5208973169365385, "COMIRNATY": 0.1611437153367623, "ELIQUIS": 0.5796319619200778, "ENTRESTO": 6.928718050347364, "INSULIN": 2.77865123651755, "JANUMET": 2.764523073516944, "LEVETIRACETAM": 2.6927629518092417, "MICARDIS": 5.381390153472279, "MIDAZOLAM": 4.095633973629155, "OLANZAPINE": 1.5042842967643038, "OPTIMARK": 3.5895976354178023, "PEGINTRON": 1.1972866365520043, "SILDENAFIL": 6.762607013923545, "SPIKEVAX": 0.1614958771416304, "TASIGNA": 6.119246912935201, "TELMISARTAN": 12.13198423660111, "TESTOSTERONE": 46.41696567317301, "TOZINAMERAN": 0.3580202914806766, "VALSARTAN": 21.03672978620776, "VAXZEVRIA": 0.0495782754525808, "ZOSTAVAX": 5.636138034493591, "ZYPREXA": 5.813500893793271, "null": 1.6907839009221353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6905.json
index ccdd4619ba1..46ed2c1f1f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6905.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6905.json
@@ -1 +1 @@
-{"null": 34.32186596818659}
\ No newline at end of file
+{"RIOCIGUAT": 20394.860412082395, "SILDENAFIL": 390.88721284453896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6906.json
index be59196a73f..d132df6225f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6906.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6906.json
@@ -1 +1 @@
-{"BENLYSTA": 2.634514958563839, "COMIRNATY": 2.88929836282156, "COVID19": 2.6820752201189526, "ENBREL": 4.158137704256864, "ESBRIET": 2.865370167294917, "FASENRA": 3.2093941570550384, "HUMIRA": 3.3658356911039164, "KAFTRIO": 3.699865485357378, "MEPOLIZUMAB": 1.391363690135996, "NUCALA": 1.83893858235754, "OPSUMIT": 1.1806841385602749, "SPIKEVAX": 2.231196819630564, "TOZINAMERAN": 2.744278707777292, "TRELEGY": 3.9332992533586766, "VAXZEVRIA": 2.1810521136909298}
\ No newline at end of file
+{"APIDRA": 4.660191677880037, "ARAVA": 0.352783515305773, "ATRIPLA": 0.4598213621403465, "AVANDIA": 4.68164557239068, "COMIRNATY": 0.0900239073716509, "FORXIGA": 6.278320630749732, "HUMALOG": 5.516417155492803, "HUMIRA": 3.406994957973623, "INSULIN": 5.440592901840442, "INVOKANA": 213.12920258511377, "JARDIANCE": 16.602209425911745, "LANTUS": 25.483652478395, "LEVEMIR": 17.196143931356495, "OPTIMARK": 4.503459517076035, "PLAVIX": 1.2462469936998442, "SIMPONI": 1.611892959483185, "STELARA": 1.283118918846202, "VAXZEVRIA": 0.0970732397874494, "VELTASSA": 19.24300274765625, "null": 0.6301536938569846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6907.json
index 8ec153407f8..718718a6384 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6907.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6907.json
@@ -1 +1 @@
-{"null": 1.3092049495297184}
\ No newline at end of file
+{"null": 1.3666240747328695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6908.json
index 378ae23fb40..44bf6be9511 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6908.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6908.json
@@ -1 +1 @@
-{"null": 4.035193906684829}
\ No newline at end of file
+{"CICLOSPORIN": 17.334249578503854, "null": 0.4095079342717053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6909.json
index 03f40f8c977..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6909.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6909.json
@@ -1 +1 @@
-{"ANORO": 133.00329837308163, "null": 1.0659771836943115}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/691.json
index 55896f4ff1a..718718a6384 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/691.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/691.json
@@ -1 +1 @@
-{"null": 1.7205111163459308}
\ No newline at end of file
+{"null": 1.3666240747328695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6910.json
index c1978c736bc..8608b3869d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6910.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6910.json
@@ -1 +1 @@
-{"ARAVA": 1.4328292994245562, "CIMZIA": 4.117240292312848, "KEYTRUDA": 6.525933753424509, "PEGASYS": 8.894496582030062, "PEGINTERFERON": 44.70135045759712, "PEGINTRON": 8.498278330957756, "SIMPONI": 8.979997762353072}
\ No newline at end of file
+{"COMIRNATY": 0.6375619813978909, "null": 1.1984947128811143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6911.json
index 0cd6a19f929..999f32d1497 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6911.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6911.json
@@ -1 +1 @@
-{"ELIQUIS": 3.946128878443052}
\ No newline at end of file
+{"PAZOPANIB": 233.90928402187205, "null": 0.8245393298488204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6912.json
index 9dcd7efdffa..692baf07437 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6912.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6912.json
@@ -1 +1 @@
-{"ANAKINRA": 56.50407474955294, "CIMZIA": 1.0206080250954492, "ELIQUIS": 7.269941104295416, "ENBREL": 1.4848239566250487, "ESBRIET": 4.371943654493496, "EVISTA": 4.563114965574401, "FASLODEX": 1.755909671918785, "HUMIRA": 1.0848768562828857, "IBRANCE": 8.379666530052425, "INLYTA": 2.2595050961575143, "LYRICA": 3.141320055436205, "METHOTREXATE": 1.1787617598913367, "MISOPROSTOL": 50.67295901262548, "OMALIZUMAB": 6.218314566471951, "OPSUMIT": 2.9325382977160577, "PEGFILGRASTIM": 17.390031690283337, "REVATIO": 4.929919761129982, "REVLIMID": 6.99222647796845, "RINVOQ": 3.5624446881862863, "STELARA": 1.3223917728864425, "SUTENT": 1.8846379228666088, "TOZINAMERAN": 2.925177588176418, "TRELEGY": 2.34040032383598, "VAXZEVRIA": 1.046206878186836, "VIAGRA": 1.9262275783006728, "VOTRIENT": 2.405848850274854, "XALKORI": 4.601415207929729, "XARELTO": 5.562793845876686, "XELJANZ": 4.894800127737206, "XOLAIR": 1.5775729595065155, "XTANDI": 1.0722629039497034}
\ No newline at end of file
+{"VOTRIENT": 128.5271986993595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6913.json
index 9df662f9f6d..bd00e3b521a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6913.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6913.json
@@ -1 +1 @@
-{"ABATACEPT": 1.695540427766428, "AFINITOR": 4.731246349273605, "ALIMTA": 4.386769903852649, "ARAVA": 8.333499679342365, "BEVACIZUMAB": 4.831504052308411, "BUSULFAN": 2.6548958598537378, "CARMUSTINE": 8.267271925146948, "CIMZIA": 1.9187110881020293, "CUBICIN": 6.436333795181152, "DEXAMETHASONE": 1.1765512382949963, "DOXORUBICIN": 3.965623405448583, "ENBREL": 8.985311818759836, "ENTYVIO": 3.495428154083084, "IBRANCE": 1.5811923347740673, "IPILIMUMAB": 5.0893657882930885, "IRESSA": 6.662793842786507, "KEYTRUDA": 9.431170679849703, "LEFLUNOMIDE": 5.859949083856921, "LYNPARZA": 2.8325182373035886, "MEKINIST": 1.540929636925576, "METHOTREXATE": 2.107913105681306, "MIDAZOLAM": 2.8981808990452955, "MULTAQ": 8.409473394434361, "NEULASTA": 6.231656427254602, "OPDIVO": 15.986156831300322, "PEMBROLIZUMAB": 8.069315406345059, "PEMETREXED": 7.914760144598592, "RITUXIMAB": 10.935116694941216, "TAGRISSO": 63.23391072785357, "VECTIBIX": 12.159814541873336, "null": 1.403477329361745}
\ No newline at end of file
+{"null": 1.5494092413988425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6914.json
index 0e6368d2efc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6914.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6914.json
@@ -1 +1 @@
-{"ABACAVIR": 4.683215957035845, "AMINOSALICYLIC": 37.58363606480747, "BEDAQUILINE": 59.616926898268304, "CELLCEPT": 11.212835071791746, "CICLOSPORIN": 7.811291026254513, "CIMZIA": 3.239577667191264, "COMBIVIR": 9.36722900056363, "DELAMANID": 20.908291992416935, "DEXAMETHASONE": 2.6569342191727223, "EFAVIRENZ": 16.97020560875137, "HUMIRA": 4.447103881061256, "INFLIXIMAB": 18.702202370765622, "JAKAVI": 9.14120829862694, "KALETRA": 9.92958838410139, "KEYTRUDA": 1.8641944512605093, "LAMIVUDINE": 11.216014152130064, "LEVOFLOXACIN": 4.925521034088022, "METHOTREXATE": 5.99254688417585, "MYCOPHENOLATE": 9.78638286146358, "NEXAVAR": 2.0155529752909755, "PEGASYS": 2.913748357730022, "PEGINTERFERON": 9.361609573384415, "PEGINTRON": 3.2402997459025897, "REMICADE": 12.658438972541102, "ROACTEMRA": 6.057486210905966, "RUXOLITINIB": 14.872243484455126, "SIMPONI": 20.26155849850413, "SIRTURO": 70.57367086101097, "STELARA": 1.437309223951646, "TREMFYA": 6.425285551667952}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6915.json
index a01f0532d05..66906bfc712 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6915.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6915.json
@@ -1 +1 @@
-{"CYMBALTA": 28.8072066431291}
\ No newline at end of file
+{"ASPARAGINASE": 252.46334778932453, "BOTULINUM": 195.3323345656717, "KEPPRA": 39.79515093739546, "null": 0.665188427183345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6916.json
index 03983cbfb60..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6916.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6916.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 49.95312312673681, "null": 2.0751911590576877}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6917.json
index a9ccaceae9d..3c076876e30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6917.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6917.json
@@ -1 +1 @@
-{"ASPARAGINASE": 40.59039606917415, "KEPPRA": 3.2678817240477334, "null": 7.223069845857267}
\ No newline at end of file
+{"null": 0.915279293440222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6918.json
index edab57293e1..05047f3991a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6918.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6918.json
@@ -1 +1 @@
-{"null": 13.446099804105032}
\ No newline at end of file
+{"null": 1.4631204102819515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6919.json
index dbc213a91c7..354e8934d8f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6919.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6919.json
@@ -1 +1 @@
-{"METHOTREXATE": 20.16678976526278, "MIDAZOLAM": 73.89671725978071}
\ No newline at end of file
+{"null": 1.7317832483497315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/692.json
index 0319e13b529..c1d464b3a32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/692.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/692.json
@@ -1 +1 @@
-{"ANAKINRA": 100.15806602655712, "ARAVA": 2.4766295204909543}
\ No newline at end of file
+{"GARDASIL": 10.72942061592284, "null": 1.5678028944258715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6920.json
index c2ab53a64a0..7e381668730 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6920.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6920.json
@@ -1 +1 @@
-{"LYRICA": 189.433727430944}
\ No newline at end of file
+{"BRAFTOVI": 78.7446942258701, "COSENTYX": 44.74125373909181, "VFEND": 48.173506867500194, "null": 0.2367531576646698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6921.json
index 8383f4ab12e..65c1ca081dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6921.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6921.json
@@ -1 +1 @@
-{"ANORO": 1051.523204597621, "APIXABAN": 104.51541727514372, "AZATHIOPRINE": 62.82146623877089, "HUMIRA": 12.26730195400268}
\ No newline at end of file
+{"CIALIS": 1389.5915893463423, "VIAGRA": 177.21213866619368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6922.json
index 2f9258da1e9..84bbb05ac4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6922.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6922.json
@@ -1 +1 @@
-{"BUSULFAN": 113.54709767033808, "OPSUMIT": 50.883443068640695, "TRACLEER": 23.360554708260626}
\ No newline at end of file
+{"TELMISARTAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6923.json
index 3763a98cfce..c1c8906f1ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6923.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6923.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7034497875731798, "ELIQUIS": 3.1498690574462844, "ROACTEMRA": 25.1759905446634, "SUTENT": 1.7169802751743857}
\ No newline at end of file
+{"null": 0.809811682955197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6924.json
index dbb73c2451b..3189028551c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6924.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6924.json
@@ -1 +1 @@
-{"ATRIPLA": 6.9454398154350185, "null": 1.022803258843102}
\ No newline at end of file
+{"LAMIVUDINE": 201.357822559237, "null": 1.694721013906438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6925.json
index cf50832a760..352abcf2d6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6925.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6925.json
@@ -1 +1 @@
-{"COMIRNATY": 1.519736680754068, "GARDASIL": 1.9182632482901625, "JANUMET": 2.40640090005485, "NIMENRIX": 3.518928172618143, "SUBOXONE": 1.8932610650065544, "TOZINAMERAN": 1.0702633731489972, "TWINRIX": 5.638753836212602, "VAXZEVRIA": 1.27648305914103, "ZOSTAVAX": 1.2916458810461853, "null": 1.2468255283038965}
\ No newline at end of file
+{"ASPARAGINASE": 629.9935959036418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6926.json
index b50657ea0e2..20e26a1aa7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6926.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6926.json
@@ -1 +1 @@
-{"ASPARAGINASE": 3.5508766527768394, "BUPRENORPHINE": 2.7437927120993386, "CYTARABINE": 3.5795845893407408, "FENTANYL": 10.95795401798436, "GLUCAGON": 88.60645199749415, "IBUPROFEN": 1.9362945647873149, "KALETRA": 3.3577334634366665, "MIDAZOLAM": 11.9988486016156, "MIRCERA": 44.575794100875946, "OLANZAPINE": 5.014710812951462, "null": 3.2276635671726743}
\ No newline at end of file
+{"CICLOSPORIN": 33.27616837579484, "null": 0.9941356751398872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6927.json
index 2f0d7eabb74..d8bd9431abc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6927.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6927.json
@@ -1 +1 @@
-{"null": 1.656573125686241}
\ No newline at end of file
+{"ABILIFY": 0.6798511157117791, "ADALIMUMAB": 0.0587469239011509, "ADEMPAS": 1.2489347825872583, "AFINITOR": 0.7174269039612449, "AIMOVIG": 0.2939819079839736, "AMIKACIN": 0.6596059635595551, "APIDRA": 0.2601826492010973, "APIXABAN": 0.1471909603664473, "ARANESP": 0.5005458230211107, "ARAVA": 0.0504299984151271, "ARIPIPRAZOLE": 0.4942209976301036, "ASPARAGINASE": 1.0146194655975578, "ATAZANAVIR": 0.3063045002551815, "ATRIPLA": 0.0639169856363175, "AUBAGIO": 0.2341996539667039, "AVANDIA": 0.1458568483158684, "AVASTIN": 0.3645797291706965, "AZATHIOPRINE": 0.3908500039382023, "AZILECT": 1.9361525551742127, "BENLYSTA": 0.3324515866470287, "BEVACIZUMAB": 0.301912459496539, "BEXSERO": 4.8320162609010895, "BIKTARVY": 0.3788581891713411, "BRINTELLIX": 0.1285797884272981, "BUMETANIDE": 3.227079935636893, "BUPIVACAINE": 2.432142034314393, "BUPRENORPHINE": 0.8106208021404766, "BYDUREON": 2.346557249007125, "BYETTA": 0.3911557821606522, "CABOMETYX": 0.2669506959638275, "CANNABIDIOL": 4.37397642326073, "CAPECITABINE": 0.3035179435430221, "CARFILZOMIB": 0.7909889954968884, "CASPOFUNGIN": 1.641417808187857, "CELECOXIB": 0.4063171456149099, "CELLCEPT": 0.1129599772682944, "CHAMPIX": 1.6365640181779608, "CICLOSPORIN": 0.3701435662970268, "CIMZIA": 0.1161433841727015, "CLOPIDOGREL": 0.3737412784804835, "COMBIVIR": 0.5194304605635591, "COMIRNATY": 1.414361329608882, "COSENTYX": 0.2323260349181058, "CRIXIVAN": 1.2023407872613594, "CYMBALTA": 6.884821138976774, "CYTARABINE": 0.2790690962408629, "DARATUMUMAB": 5.012191801092992, "DASATINIB": 1.759573185269558, "DELAMANID": 2.526978350067973, "DEXAMETHASONE": 0.4054308501486031, "DOCETAXEL": 0.2328275155033357, "DULOXETINE": 0.4923687035192346, "EFAVIRENZ": 0.6066845835561466, "ELIQUIS": 0.247162375282185, "EMPAGLIFLOZIN": 1.7492003885500913, "ENBREL": 0.089944581983509, "ENTRESTO": 1.0634708487389448, "ENTYVIO": 0.2384235597291464, "EPCLUSA": 0.6867595431984949, "EPIVIR": 0.58754325130755, "ESBRIET": 0.983156567316826, 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0.676101077829301, "OPTIMARK": 0.1562316605357284, "ORENCIA": 2.4815247355441588, "OXYBUTYNIN": 1.5522422876977415, "PEGASYS": 0.8385397222631112, "PEGINTERFERON": 1.590463474064481, "PEGINTRON": 0.5704940388195936, "PEMBROLIZUMAB": 0.4044700518505906, "PLAVIX": 0.3100544358486001, "PLEGRIDY": 0.3319892737296794, "PRADAXA": 0.9588534342484614, "PREGABALIN": 0.668678226575584, "PREVENAR": 1.7819862902777008, "PRIVIGEN": 0.6977787817652203, "PROPRANOLOL": 1.052155477455494, "RANEXA": 1.3446069553506803, "REVLIMID": 0.5966450662995305, "RIBAVIRIN": 0.9052279428765416, "RINVOQ": 0.5577589222704643, "RISPERIDONE": 7.957249694101176, "RITUXIMAB": 0.5325369326897691, "ROTARIX": 5.092917150057466, "ROTATEQ": 5.142984259217696, "RUBRACA": 0.9960791749218152, "SAXENDA": 0.7781099077850453, "SHINGRIX": 0.3572706278300201, "SILDENAFIL": 0.4377854313993375, "SIMPONI": 0.0786228896844849, "SOLIRIS": 0.6265403621519048, "SPIKEVAX": 0.6494386688619342, "SPINRAZA": 0.5781869745918127, "STELARA": 0.9689183731757074, "STIVARGA": 0.173809557139438, "SUBOXONE": 1.260060786316063, "SUTENT": 0.4143553066139981, "SYNAGIS": 0.980520708081389, "TACROLIMUS": 0.7460363031890548, "TAMIFLU": 0.9207329248608206, "TASIGNA": 0.2255184575548409, "TEDUGLUTIDE": 5.576677379220881, "TOPOTECAN": 1.172465362303751, "TOVIAZ": 0.3826262107457492, "TOZINAMERAN": 2.999863403427596, "TRACLEER": 0.5459633527694826, "TRELEGY": 0.1641074828393774, "TRULICITY": 0.5189689573498447, "TRUVADA": 0.0687278413755652, "VAXZEVRIA": 2.106117454528896, "VICTOZA": 0.2038486723820029, "VIMPAT": 1.1725200867694852, "VOTRIENT": 0.7633836875962124, "XALKORI": 0.449154260451153, "XELJANZ": 0.185197264509693, "XOLAIR": 0.5119849213215982, "XTANDI": 1.280372847363651, "XYREM": 3.511171568626322, "ZOSTAVAX": 0.3496095871455512, "ZYPADHERA": 1.4443290526086083, "ZYPREXA": 1.2606588846802216, "null": 0.8281734020071486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6928.json
index 8c1ab801a0c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6928.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6928.json
@@ -1 +1 @@
-{"COMIRNATY": 2.799662579195312}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6929.json
index 8b9782c1506..a32146a9f70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6929.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6929.json
@@ -1 +1 @@
-{"BORTEZOMIB": 36.52636557711005, "BRIDION": 52.31824740364951, "BUPIVACAINE": 13.45264252630654, "CARFILZOMIB": 12.880417950559016, "DEXAMETHASONE": 2.4729562542430847, "FENTANYL": 16.118523571107573, "FESOTERODINE": 1101.004184712733, "GLUCAGON": 64.35217573762536, "IBUPROFEN": 5.7802075477885255, "MIDAZOLAM": 15.491618592603688, "OFEV": 14.659397352398202, "OPSUMIT": 4.8811637415524745, "REMDESIVIR": 51.05635158737004, "TRACLEER": 3.031727869409328, "null": 1.9129220082989813}
\ No newline at end of file
+{"null": 12.211406795950555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/693.json
index 16c3e91a7ae..f867424ac37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/693.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/693.json
@@ -1 +1 @@
-{"APTIVUS": 209.5312950032599, "KEYTRUDA": 4.52972881642863, "NEXAVAR": 8.290245484033543, "OCALIVA": 79.22118340654633, "PEGASYS": 2.097610924178935, "QARZIBA": 262.8945304909362}
\ No newline at end of file
+{"ABILIFY": 6.919282397095749, "BRINTELLIX": 41.679074451275135, "CYMBALTA": 4.2948299796423575, "PREGABALIN": 11.797632611204277, "VIAGRA": 26.84877206451416, "null": 4.814549830256814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6930.json
index 1cbbe2e8f0c..b9b7249ed4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6930.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6930.json
@@ -1 +1 @@
-{"NEVANAC": 158.59345767120948, "ZOSTAVAX": 24.865210097230374, "null": 2.2636491077386136}
\ No newline at end of file
+{"null": 2.653709282728216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6931.json
index 1e5c81cd5d1..fec758819df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6931.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6931.json
@@ -1 +1 @@
-{"COVID19": 14.377338801613528}
\ No newline at end of file
+{"ABILIFY": 32.40651090492601, "ARANESP": 0.9270983305022288, "ARIPIPRAZOLE": 29.13410432258982, "ASPARAGINASE": 3.2715742746403347, "BOSULIF": 3.4997137297925662, "BUSULFAN": 3.0942402061274064, "CHLORMETHINE": 78.27003535870135, "CICLOSPORIN": 0.4442570479073064, "COMIRNATY": 0.0876019678744384, "COSENTYX": 0.5367049994329824, "CRESEMBA": 15.208481165981857, "CYTARABINE": 3.5443285638424578, "DEXAMETHASONE": 1.0543798980440495, "DOXORUBICIN": 3.910483703794333, "ELIQUIS": 1.9111259438521493, "EXJADE": 14.559671672923406, "FORSTEO": 2.091603351736853, "GARDASIL": 0.525911343927395, "HUMALOG": 1.843186085260235, "IBRANCE": 0.5197724641666265, "JAKAVI": 14.987967603259468, "JARDIANCE": 0.5805633950864953, "KEPPRA": 1.5609438057680027, "LANTUS": 2.176728911141878, "LEVEMIR": 1.7641490129697397, "LYNPARZA": 7.244958886068466, "METHOTREXATE": 1.212697573254, "NEULASTA": 2.069665565522324, "NOXAFIL": 21.38399227889401, "NPLATE": 5.240278610971806, "OLANZAPINE": 0.8429878421938651, "PEGASYS": 0.3164008903574584, "PLAVIX": 1.1178636397903123, "SIMPONI": 1.6241320533142398, "SOLIRIS": 1.9556410124965964, "SPIKEVAX": 0.112237610993593, "SPRYCEL": 9.608490019694605, "STELARA": 1.728432151375854, "TASIGNA": 2.132192196421577, "TOZINAMERAN": 0.2002784751265771, "VAXZEVRIA": 0.0277832324248661, "VFEND": 30.19362380106578, "VIAGRA": 1.8045259152077688, "XELJANZ": 1.2590897021856733, "XOLAIR": 1.9374177765361331, "ZOSTAVAX": 0.682961596852592, "null": 1.2157654622367058}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6932.json
index b5f4f163117..e43b6a45e2a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6932.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6932.json
@@ -1 +1 @@
-{"COMIRNATY": 2.4105878439243185, "SPIKEVAX": 2.9954461370993446}
\ No newline at end of file
+{"null": 0.7301470786831146}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6933.json
index 0194702ed38..8a45226886b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6933.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6933.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7862105792281946}
\ No newline at end of file
+{"ALEMTUZUMAB": 22.33921857858218, "ARSENIC": 1480.678075625734, "ASPARAGINASE": 39.38746816765458, "BLINATUMOMAB": 98.04356151587376, "BUSILVEX": 121.42520941204472, "BUSULFAN": 70.85263174599095, "CASPOFUNGIN": 36.85167843717864, "CICLOSPORIN": 20.45602249888468, "CLOFARABINE": 77.08779789168332, "CYTARABINE": 28.267523141071106, "EXJADE": 4.742938287362217, "ICLUSIG": 31.68209624846668, "KYMRIAH": 10.81243580264405, "MERCAPTOPURINE": 32.24348423788619, "METHOTREXATE": 9.148383840212336, "NOXAFIL": 24.593829632849364, "SPRYCEL": 11.617710539545142, "TASIGNA": 16.501581781244955, "VFEND": 21.148782131931178, "null": 0.2134655006519779}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6934.json
index 7b6a2a9d862..f94e489dea5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6934.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6934.json
@@ -1 +1 @@
-{"ANGIOX": 603.795835892118, "CLOPIDOGREL": 17.030212021236384, "ELIQUIS": 6.5223287080144505, "PLAVIX": 10.865019481166508, "null": 1.4736440920628302}
\ No newline at end of file
+{"null": 2.285765013860217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6935.json
index afaa841b57a..1d42356c568 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6935.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6935.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9605312713471597, "SPIKEVAX": 1.2524756454097568}
\ No newline at end of file
+{"OLANZAPINE": 548.9561038957594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6936.json
index 16d0ff6943b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6936.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6936.json
@@ -1 +1 @@
-{"COMIRNATY": 6.989963951316693, "COVID19": 1.1951601441666893, "SPIKEVAX": 2.2103855848006937}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6937.json
index b722f562b46..54ce361be21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6937.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6937.json
@@ -1 +1 @@
-{"COMIRNATY": 9.072289467127945, "COVID19": 2.066090346390676, "SPIKEVAX": 2.131367919443887}
\ No newline at end of file
+{"null": 4.29790114419221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6938.json
index 8f764ca1962..65899f69291 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6938.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6938.json
@@ -1 +1 @@
-{"COMIRNATY": 5.196563295091902, "SPIKEVAX": 2.712860085117506}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6939.json
index c09ca4cb176..d1848784150 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6939.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6939.json
@@ -1 +1 @@
-{"COMIRNATY": 4.017291734526552, "SPIKEVAX": 4.278361561000895}
\ No newline at end of file
+{"COMIRNATY": 0.1398415559265132, "JARDIANCE": 11.058450616075968, "null": 1.2598773869018864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/694.json
index 5b14cca6713..adce439a38b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/694.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/694.json
@@ -1 +1 @@
-{"null": 1.9487373135158736}
\ No newline at end of file
+{"AIMOVIG": 0.2934445238776547, "APIXABAN": 18.571421440031315, "AUBAGIO": 0.4438595585190138, "AVAMYS": 7.538387342589545, "BENLYSTA": 1.0409252216528633, "BRINTELLIX": 0.6475986472856713, "CHAMPIX": 1.687337774794429, "COMIRNATY": 2.387265662850641, "COSENTYX": 0.4693248365463076, "CYMBALTA": 0.133019562934147, "ELIQUIS": 0.1203243686956081, "FASENRA": 1.853821510865839, "FIRDAPSE": 2.156678766324315, "IBRANCE": 0.4331744441868925, "KEPPRA": 0.3521712440581328, "LEVOFLOXACIN": 0.2909964486548324, "MICARDIS": 1.1368650760571264, "MODERNA": 1.5894208809691852, "NUCALA": 1.2265599629103692, "OMALIZUMAB": 0.5901588884809965, "RELVAR": 2.091614902948057, "SIMPONI": 0.4543130097527335, "SPIKEVAX": 1.5460780922068775, "STELARA": 0.5348343442511752, "SUTENT": 0.1141114852980069, "TAMIFLU": 0.8360923620608477, "TOZINAMERAN": 2.8076777477196586, "VAXZEVRIA": 1.4499713552512727, "XELJANZ": 0.3331376754004376, "XOLAIR": 0.3226760571761295, "ZOSTAVAX": 0.2233797249068792, "null": 0.907467166860834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6940.json
index e397794f228..ecc7168becd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6940.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6940.json
@@ -1 +1 @@
-{"COMIRNATY": 2.1389082728335675, "SPIKEVAX": 2.334604192650971}
\ No newline at end of file
+{"KEYTRUDA": 25.21236657763913, "OPDIVO": 230.95446120214768, "null": 0.4140489676554496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6941.json
index 7d8bc4f4711..4e21f5f4a85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6941.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6941.json
@@ -1 +1 @@
-{"FENTANYL": 11.73583860964222, "GARDASIL": 1.7703965323268829, "GLUCAGON": 82.10159750584485, "NALOXONE": 95.07926110935236, "OLANZAPINE": 3.603821993950385, "null": 3.06080787153008}
\ No newline at end of file
+{"GARDASIL": 132.95789170707545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6942.json
index 9c6bd126e4c..834c142fcad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6942.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6942.json
@@ -1 +1 @@
-{"null": 5.194688139804288}
\ No newline at end of file
+{"ALIMTA": 5.458262979281818, "ASPARAGINASE": 20.430810276701774, "AVASTIN": 8.226757427218484, "BEVACIZUMAB": 3.8861770015443535, "BUSULFAN": 6.550576585994994, "CELLCEPT": 5.6695670056871705, "CICLOSPORIN": 12.013560356442076, "COMIRNATY": 0.0620958409424041, "CYTARABINE": 15.70552442011438, "DEXAMETHASONE": 1.7206476724066968, "DOCETAXEL": 4.174868794844409, "IRESSA": 9.047228067410376, "IRINOTECAN": 7.302081364250778, "KEYTRUDA": 1.146101451048359, "METHOTREXATE": 17.076993447106204, "NEXAVAR": 2.7692695604274853, "PEGASYS": 0.5720790199319974, "SUTENT": 2.124453921167601, "TEMODAL": 12.398851522272532, "XELODA": 12.439607280393512, "null": 1.3083442204923172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6943.json
index 4ca4bda7a6b..b758c8aa2b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6943.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6943.json
@@ -1 +1 @@
-{"null": 1.934474741551776}
\ No newline at end of file
+{"null": 2.222531818087429}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6944.json
index e873accc9cf..9a4f3016855 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6944.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6944.json
@@ -1 +1 @@
-{"null": 3.010743156584658}
\ No newline at end of file
+{"ABACAVIR": 1.6168192170376663, "ABILIFY": 4.380137926039308, "ABRAXANE": 1.6073354293329676, "ADALIMUMAB": 0.2557986526381032, "ADCETRIS": 2.2654616869853546, "ADENURIC": 0.908210002253096, "ADVAGRAF": 5.1725678699526325, "AERIUS": 0.5090546445387546, "AFINITOR": 0.650661083368665, "ALDARA": 1.3615922854864158, "ALEMTUZUMAB": 1.213222803525895, "ALIMTA": 5.363617814284812, "AMIKACIN": 2.6576950295137056, "APROVEL": 0.4598446221189446, "ARANESP": 0.7387975496415746, "ARAVA": 0.8115857306392567, "ARIPIPRAZOLE": 9.872595210261888, "ASPARAGINASE": 1.3619846638923223, "ATAZANAVIR": 1.2727816958870353, "AUBAGIO": 1.931193436522311, "AVANDIA": 0.1438827109610123, "AVASTIN": 2.771116943499772, "AZACITIDINE": 2.6178500018659685, "AZATHIOPRINE": 2.3915785812355157, "BARACLUDE": 1.4152125388571977, "BASILIXIMAB": 5.886658379164298, "BEDAQUILINE": 0.9311885566148372, "BELIMUMAB": 1.9421029351983576, "BENLYSTA": 1.4980039980397395, "BETAFERON": 2.845303757291461, "BEVACIZUMAB": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6945.json
index e6c4e754c56..2c261eeb256 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6945.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6945.json
@@ -1 +1 @@
-{"BUDESONIDE": 1.9971596710564317, "FENTANYL": 3.052718071617359, "JETREA": 415.64417923908906, "MIDAZOLAM": 17.40373183429188, "null": 3.763455498770373}
\ No newline at end of file
+{"null": 1.9007439671806237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6946.json
index aaf12b34ed9..1f799e343fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6946.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6946.json
@@ -1 +1 @@
-{"null": 3.780429654414673}
\ No newline at end of file
+{"COMIRNATY": 0.4828381944274298, "null": 0.5597033245598385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6947.json
index 0f601593120..22e3ae23b8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6947.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6947.json
@@ -1 +1 @@
-{"null": 1.9147619606564508}
\ No newline at end of file
+{"null": 1.7291211293279931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6948.json
index 7228770ff15..601c0c8268b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6948.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6948.json
@@ -1 +1 @@
-{"null": 9.072198172684706}
\ No newline at end of file
+{"null": 1.4245068139663926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6949.json
index 901f5ba9dbe..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6949.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6949.json
@@ -1 +1 @@
-{"ADEMPAS": 2.712762989969136, "ALIMTA": 2.9734339382927057, "ANAKINRA": 1.2094427446228568, "BETMIGA": 2.520140639626995, "BRILIQUE": 3.613179201347502, "CANCIDAS": 3.0718095777952747, "CIRCADIN": 10.53706242415973, "CLOPIDOGREL": 3.7683194500790975, "COTELLIC": 7.653219576577805, "CUBICIN": 2.030812692706112, "ELIQUIS": 2.1583919059620293, "ENOXAPARIN": 4.228419939763872, "INCIVO": 1.1249417926014644, "IRESSA": 2.414375016645368, "LEMTRADA": 1.0083860651992462, "LEVOFLOXACIN": 1.8596780193649611, "LIXIANA": 3.008567848157621, "MIMPARA": 3.4626281311087963, "NEXAVAR": 1.345244396559795, "NOVONORM": 4.640106985486704, "NPLATE": 4.146955793793382, "PEGASYS": 1.0703372448336672, "PEGINTERFERON": 1.0783618243471158, "PEGINTRON": 1.0587707795861023, "PLAVIX": 4.32140517014488, "PREVENAR": 6.663251033504417, "ROACTEMRA": 1.083231877757867, "TAGRISSO": 1.3290459366813194, "TAMIFLU": 1.0059141063049428, "TEMODAL": 4.512247378692203, "TICAGRELOR": 2.5606403193661684, "XARELTO": 3.444562522533756, "null": 2.433881446032224}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/695.json
index d89f2f4c12c..85c1375ffae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/695.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/695.json
@@ -1 +1 @@
-{"ABRAXANE": 1.4488652443574392, "ACTOS": 3.0329275753086717, "ADCIRCA": 1.0973001500086363, "ADEMPAS": 1.1318325961050395, "AFINITOR": 1.1557379059382804, "AGENERASE": 9.483824023165434, "ALIMTA": 2.2557852986376656, "ALL": 2.28943919081107, "ALOXI": 6.008725020825621, "AMINOSALICYLIC": 2.460328287989767, "APREMILAST": 2.6935852788759296, "APROVEL": 1.280121264624467, "ARANESP": 4.0838081395885, "ARIPIPRAZOLE": 1.396133873049954, "ASPARAGINASE": 2.2330382872602685, "ATAZANAVIR": 2.363250553784149, "AUBAGIO": 1.8543121499384652, "AVANDIA": 2.002514034589882, "AVELUMAB": 2.667095024285793, "AXITINIB": 4.500276336044569, "AZATHIOPRINE": 1.8300339817764104, "AZILECT": 1.754636650797656, "BARACLUDE": 3.077827369054901, "BASILIXIMAB": 1.1392692695223623, "BAVENCIO": 3.1973963114176462, "BEDAQUILINE": 13.235145261287148, "BETAFERON": 4.192710698141751, "BEVACIZUMAB": 1.2822657672300273, "BOSULIF": 3.899898913275789, "BRAFTOVI": 1.174072563852717, "CABOMETYX": 3.6081366697251753, "CANCIDAS": 8.136862780168219, "CAPECITABINE": 1.539939475148664, "CASPOFUNGIN": 1.244303230012168, "CELECOXIB": 2.302460070784132, "CELLCEPT": 1.1751639580411384, "CELSENTRI": 4.224863391685897, "CICLOSPORIN": 1.6145451553321035, "COBIMETINIB": 3.2532484745277603, "COMBIVIR": 4.403588150559111, "COMTAN": 2.654184920927416, "COTELLIC": 2.138368435203255, "CRIXIVAN": 4.02641241691822, "CUBICIN": 3.308233065245218, "CYMBALTA": 1.6769634913665208, "CYTARABINE": 1.8527729259121408, "DACLATASVIR": 3.347161770117708, "DELAMANID": 6.72876353109185, "DENOSUMAB": 3.1289530340819973, "DOCETAXEL": 1.1579830377058051, "EBIXA": 1.276273827484385, "EFAVIRENZ": 6.434226550716912, "EMEND": 2.316588152999061, "EMTRICITABINE": 2.5333785524531174, "ENBREL": 3.598534707494162, "ENFUVIRTIDE": 7.772110674524519, "ENOXAPARIN": 1.0556832873739106, "ENTECAVIR": 4.788736362466789, "EPIDYOLEX": 4.207544208629049, "EPIVIR": 4.619391561027788, "ERBITUX": 2.1226259306709823, "ESMYA": 4.820145516433019, "ESOMEPRAZOLE": 1.6077084133929769, "EUCREAS": 1.9203125978453512, "EXFORGE": 1.133501775391796, "EXJADE": 5.962000952914598, "EXVIERA": 2.1070799263250666, "FASLODEX": 1.3660524477494076, "FEBUXOSTAT": 1.9082603395487236, "FULVESTRANT": 2.349733571990744, "FUZEON": 10.08115173824039, "GALVUS": 4.082101635048918, "GANCICLOVIR": 1.7725679282902715, "GEFITINIB": 2.2138362594757086, "GLIBENCLAMIDE": 1.2624476736539552, "GLIVEC": 3.002318861259404, "HALAVEN": 2.167362873166672, "HEPSERA": 2.7141186718930794, "HYCAMTIN": 1.9608629612924704, "IBUPROFEN": 1.0347619862128812, "IMATINIB": 1.5356047981321808, "INLYTA": 1.0117115682476676, "INSULATARD": 2.0793497300156494, "INTRONA": 1.290995109851162, "INVIRASE": 3.5779151390378616, "IPILIMUMAB": 1.364336366319686, "IRESSA": 2.36692328552314, "ISENTRESS": 5.150247799503328, "JAKAVI": 1.564708868733027, "KAFTRIO": 6.568300969711188, "KALETRA": 2.118117043770688, "KALYDECO": 2.643279813657028, "KETEK": 5.515641905804967, "KEYTRUDA": 1.3500900777753908, "KISQALI": 9.53093687269678, "KYMRIAH": 1.017487072035844, "LAMIVUDINE": 1.886170821808056, "LENVIMA": 2.3196194220935644, "LEVOFLOXACIN": 2.251674175645048, "LOPINAVIR": 1.9707055414808032, "LUMYKRAS": 5.613064780348587, "MANNITOL": 8.81175030362971, "MAVENCLAD": 5.061810481386424, "MEKINIST": 2.023352671061999, "MERCAPTOPURINE": 1.5801799441583542, "METFORMIN": 1.5398765945515922, "METHOTREXATE": 1.205844556446653, "MICARDIS": 1.4099899589734466, "MULTAQ": 7.897331596603005, "MYCAMINE": 3.064833133077701, "NALOXONE": 3.540408714146838, "NEVIRAPINE": 1.287326045017917, "NEXAVAR": 5.725847411890204, "NORVIR": 1.903835880346333, "NOXAFIL": 2.4028057381702985, "NUBEQA": 6.011683966705379, "OCALIVA": 3.3833438359343453, "OFEV": 1.158993772355183, "OLANZAPINE": 2.1454491163332845, "OLAPARIB": 1.3658856290113954, "OLYSIO": 2.670807948973907, "ONCASPAR": 1.2988965691303531, "OPDIVO": 2.3023644968115566, "OPSUMIT": 1.3543361097526787, "ORKAMBI": 5.5892127013615776, "PACLITAXEL": 1.4549778700749765, "PALIPERIDONE": 3.1496770467135624, "PANTOPRAZOLE": 1.0288579091288497, "PAZOPANIB": 4.96016328553554, "PEGASYS": 1.8026828648219413, "PEGINTERFERON": 1.572427571524185, "PEGINTRON": 1.027862133175414, "PLAVIX": 1.0941110881877203, "PLEGRIDY": 1.5495949916277691, "PRETOMANID": 20.78805621349088, "PROPRANOLOL": 1.3390364052624226, "PROTELOS": 2.3873011206980417, "RASILEZ": 1.4518864131364888, "REBIF": 2.602214792704238, "REMDESIVIR": 14.829419653001407, "REYATAZ": 2.1683863683698887, "RIBAVIRIN": 1.2971100976125476, "RIBOCICLIB": 9.142394708369558, "RINVOQ": 1.9518361851132453, "RISPERIDONE": 2.868585812657826, "ROACTEMRA": 1.8100119022800136, "RUBRACA": 4.882063655985347, "RUXOLITINIB": 1.6018779157148897, "SAMSCA": 4.372499876593629, "SEMAGLUTIDE": 3.69442241785508, "SILODOSIN": 5.423597768572754, "SIMEPREVIR": 2.9123573867681998, "SIRTURO": 4.228994240474632, "SOMATROPIN": 1.935914283396088, "SOTORASIB": 9.902324177422711, "STIVARGA": 6.9644605263144, "SUTENT": 1.0863422620903374, "TACROLIMUS": 1.232061348491534, "TAGRISSO": 1.1227738090037926, "TAMIFLU": 1.232413943873547, "TASIGNA": 2.5276394109229448, "TAXOTERE": 1.741340746549608, "TEMODAL": 1.6104495867925048, "TENOFOVIR": 2.6535811939677347, "TIVICAY": 1.1933672044147436, "TOCILIZUMAB": 1.083033574858116, "TOPOTECAN": 1.0625519736350677, "TRACLEER": 18.86373775276574, "TRISENOX": 3.995900329829647, "TRIUMEQ": 1.2396874598394525, "TWINRIX": 1.6062637857903652, "VALDOXAN": 3.3985174221568166, "VEKLURY": 6.95137114551639, "VEMLIDY": 3.2972010100792177, "VFEND": 6.447846263701006, "VIRAMUNE": 3.878041316451128, "VORICONAZOLE": 2.587810809898663, "VOTRIENT": 4.301487648370355, "XALKORI": 5.088305198231373, "XELODA": 1.057585733101919, "YESCARTA": 2.367820508889373, "YONDELIS": 4.863140768882386, "ZEPATIER": 2.0025941408951837, "ZIAGEN": 6.535088991362754, "ZINBRYTA": 5.417595901406393, "ZOMETA": 1.803840521272693, "ZYPREXA": 4.308038550707559, "null": 1.6947751806640663}
\ No newline at end of file
+{"ABILIFY": 811.2855474573316, "ARIPIPRAZOLE": 42.15155843728424, "LURASIDONE": 275.6954898661859, "OLANZAPINE": 11.126218331054591, "null": 0.1786742162474852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6950.json
index 1d2f18dbecf..d22ea2347d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6950.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6950.json
@@ -1 +1 @@
-{"null": 1.1861990206188366}
\ No newline at end of file
+{"JAKAVI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6951.json
index b829c5dd30c..5afcb22da85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6951.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6951.json
@@ -1 +1 @@
-{"null": 1.796653513242339}
\ No newline at end of file
+{"AUBAGIO": 38.16629831937677, "COMIRNATY": 0.3425192936009217, "null": 0.4602351454915432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6952.json
index 4bb23ff2e73..00a61b35b35 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6952.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6952.json
@@ -1 +1 @@
-{"CELECOXIB": 986.279486566102, "DEXAMETHASONE": 22.567870136316973}
\ No newline at end of file
+{"ABILIFY": 2.9021596558488967, "AIMOVIG": 0.73126636244655, "ATRIPLA": 0.1395243461348519, "BIKTARVY": 3.1649080604128565, "BRINTELLIX": 19.34528017098241, "BUPIVACAINE": 6.770797633506036, "CHAMPIX": 3.200033211705383, "CIALIS": 14.529117802560044, "COMIRNATY": 0.1806128823141513, "CYMBALTA": 3.365138321046759, "ELIQUIS": 0.2366584391019291, "GARDASIL": 0.3053237410251783, "JARDIANCE": 0.6445403111242817, "KEPPRA": 0.898838722254692, "LYRICA": 1.6547532015609647, "OLANZAPINE": 1.690809001592309, "PEGASYS": 1.085131112543151, "PEGINTRON": 0.9114961187315502, "SPIKEVAX": 0.1207088324542905, "SUBOXONE": 3.7426425403829593, "TESTOSTERONE": 7.04483245600222, "TOZINAMERAN": 0.1443546165042717, "TRUVADA": 0.1932922859929391, "UROREC": 34.48602214236978, "VAXZEVRIA": 0.0681848614985179, "VIAGRA": 2.5741502400427145, "ZYPREXA": 2.4291218071755067, "null": 4.891136770587675}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6953.json
index 6186be16777..7c73e53312f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6953.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6953.json
@@ -1 +1 @@
-{"CICLOSPORIN": 4.030962722080242, "SUTENT": 2.782302584296983, "null": 1.4685365756094602}
\ No newline at end of file
+{"CHAMPIX": 4.353121827090177, "COMIRNATY": 0.1956970806853903, "ZYPREXA": 5.011274901838199, "null": 2.2913683202909403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6954.json
index 30c4ef5b623..bfe44fda155 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6954.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6954.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 17.430934757856942, "CICLOSPORIN": 7.729516825093644, "FENTANYL": 3.0781380524960458, "HUMIRA": 4.092517919917436, "IBUPROFEN": 10.35079442418304, "IRON": 32.796400513698785, "LEVOFLOXACIN": 3.204513227314988, "RINVOQ": 6.360660905819318, "null": 1.3326095279845027}
\ No newline at end of file
+{"ABILIFY": 4.702537593036408, "AIMOVIG": 30.86852741693539, "BRINTELLIX": 6.58355243381453, "CHAMPIX": 5.563645123697841, "CIALIS": 56.07065819962056, "COMIRNATY": 0.1545198269107227, "CYMBALTA": 1.2275219381482911, "OLANZAPINE": 5.217505782978675, "PANTOPRAZOLE": 8.030962357682757, "SIFROL": 68.8112909051405, "SPIKEVAX": 0.1539650529134683, "STALEVO": 20.785353313834342, "VAXZEVRIA": 0.0756180779069222, "VIAGRA": 9.50189564743061, "null": 1.8216311193925208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6955.json
index 2366bd0f6ce..a9cc995add0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6955.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6955.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.514843018978814, "ARAVA": 2.681373680423466, "AUBAGIO": 2.4676521414628523, "CICLOSPORIN": 7.25869109077661, "CIMZIA": 6.639393706416398, "COSENTYX": 23.172161021986867, "ENBREL": 2.0355784959623904, "HUMIRA": 5.002281045411307, "NEXAVAR": 2.572310224818957, "SIMPONI": 17.75636317132952, "STELARA": 41.76130811056303, "TREMFYA": 30.307479687933043}
\ No newline at end of file
+{"null": 1.0426276596056734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6956.json
index a541547c2fc..b7a5cc5a7ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6956.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6956.json
@@ -1 +1 @@
-{"AIMOVIG": 1.1066750065570206, "CICLOSPORIN": 2.552636511039637, "COSENTYX": 6.540052962106897, "ENTRESTO": 1.9891586407800328, "ENTYVIO": 1.4097655860231462, "FASENRA": 2.3954926159662078, "INCIVO": 3.872909193914136, "JARDIANCE": 2.03682098002026, "LEVOFLOXACIN": 1.921903975476623, "NEXAVAR": 2.446503208664056, "OMALIZUMAB": 1.4431428091654044, "RINVOQ": 8.548560022045779, "ROACTEMRA": 4.755863440826454, "SHINGRIX": 6.682751848251535, "SIMPONI": 1.6470535180550796, "STELARA": 2.5147368086316426, "STIVARGA": 1.8570119058244527, "TAGRISSO": 2.946345586943139, "TREMFYA": 2.655966780777625, "null": 1.7820269078666615}
\ No newline at end of file
+{"COMIRNATY": 2.6764148635088447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6957.json
index 854cf8e2ec8..fe8d8e7cba3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6957.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6957.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 10.724361031970002, "ELIQUIS": 40.70555012857368, "PLAVIX": 9.19892587962771}
\ No newline at end of file
+{"ARAVA": 0.2575427897992109, "CICLOSPORIN": 1.2495272023834705, "CIMZIA": 0.8784548412784949, "COMIRNATY": 1.3895545881611482, "COSENTYX": 4.227290604099208, "JARDIANCE": 1.2726618196900972, "KEYTRUDA": 8.40134278397217, "PEGASYS": 1.0452773946464131, "PEMBROLIZUMAB": 8.727841268758885, "SPIKEVAX": 0.7646414938397951, "TOZINAMERAN": 1.247361246788647, "TWINRIX": 7.405725764967803, "VAXZEVRIA": 0.6544236698266824, "ZOSTAVAX": 3.032275800854423, "null": 0.6615626405060627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6958.json
index a09ee541cf6..8552be738b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6958.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6958.json
@@ -1 +1 @@
-{"ASPARAGINASE": 62.71274736489988, "COMBIVIR": 24.966858157739416, "KALETRA": 27.603564096551345, "null": 1.186569475322893}
\ No newline at end of file
+{"COMIRNATY": 2.1862448216011883, "JARDIANCE": 25.348331164481177, "SPIKEVAX": 0.8916584917558616, "TOZINAMERAN": 1.49511341692274, "VAXZEVRIA": 0.4057248965419061, "null": 0.2987241563155594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6959.json
index 9d97f9bcb71..dffcf22f876 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6959.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6959.json
@@ -1 +1 @@
-{"ABACAVIR": 1.072893906840536, "ADVAGRAF": 24.124508803547105, "AMIKACIN": 4.239618964789491, "BEDAQUILINE": 4.991611056082786, "BENLYSTA": 2.23970263059006, "BYETTA": 1.5768576698027958, "CELLCEPT": 9.60698763457576, "CICLOSPORIN": 2.107859766475213, "CIMZIA": 1.969149646164128, "COMBIVIR": 6.442216334082375, "COSENTYX": 1.7635264498049978, "CRIXIVAN": 6.738935631121545, "EMPAGLIFLOZIN": 8.135602444809566, "ENBREL": 2.120893496059712, "EXJADE": 1.2245880094364152, "FORSTEO": 1.324612004284015, "FORXIGA": 36.509121217540105, "GARDASIL": 1.5299670197875526, "HUMALOG": 1.9205119721763912, "HUMIRA": 1.486580140979464, "INVOKANA": 20.150744044135763, "JAKAVI": 1.7202053982003156, "JANUMET": 1.0458785719016268, "JANUVIA": 1.064671768038865, "JARDIANCE": 24.80398482862736, "KEYTRUDA": 2.826087413081574, "LYRICA": 1.217424385753396, "MEPOLIZUMAB": 1.499414731191192, "METHOTREXATE": 2.0914427937989326, "MYCOPHENOLATE": 3.543776549256607, "OMALIZUMAB": 2.136523295454161, "PEGASYS": 1.5566995170713942, "PEGINTRON": 2.421579526196039, "REMICADE": 4.416570981206986, "ROACTEMRA": 3.860160517408251, "SIMPONI": 4.778816399039005, "SOLIRIS": 2.1887411300806843, "STELARA": 2.0191446390127448, "STIVARGA": 1.237502705675029, "TELMISARTAN": 6.255679723179492, "TOVIAZ": 2.459373624519442, "XELJANZ": 1.618075978969879}
\ No newline at end of file
+{"CICLOSPORIN": 31.805487156865176, "OPTIMARK": 45.30524993893318, "RINVOQ": 33.643037548600574, "null": 0.8742472327870493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/696.json
index 8db8add3957..ee4c18cdace 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/696.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/696.json
@@ -1 +1 @@
-{"SPIKEVAX": 28.635263974628977}
\ No newline at end of file
+{"COMIRNATY": 9.029687703071833, "CYMBALTA": 4.8857613628162415, "SPIKEVAX": 1.485110868416672, "TOZINAMERAN": 3.01071021790194, "VAXZEVRIA": 0.4882695934789044, "null": 0.0879969924931055}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6960.json
index a7cda321e08..b6a0bad03f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6960.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6960.json
@@ -1 +1 @@
-{"CELECOXIB": 42.67883411725485, "CELLCEPT": 9.882029668808537, "FORXIGA": 59.45778427360257, "JARDIANCE": 17.50308089665486, "PEGASYS": 1.6520557508716636, "SIMPONI": 2.8273420175051323, "XELJANZ": 2.029372542820046}
\ No newline at end of file
+{"ALIMTA": 7.922876019064592, "CICLOSPORIN": 1.672517832452632, "COMIRNATY": 0.2695521356916045, "ELIQUIS": 1.1981427427560447, "IPILIMUMAB": 13.016764537000531, "KEPPRA": 1.6272142798862417, "KEYTRUDA": 12.918153766282892, "OPDIVO": 6.208279406740189, "PEMBROLIZUMAB": 15.454466373047763, "PLAVIX": 1.5443188190983204, "SPIKEVAX": 0.095109835088365, "TOZINAMERAN": 0.4400989539976145, "VAXZEVRIA": 0.0657384902218437, "null": 1.2474108385918927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6961.json
index 2ca3bbc391c..f3d9ac3b98a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6961.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6961.json
@@ -1 +1 @@
-{"BEDAQUILINE": 101.42117345549948, "FORXIGA": 49.51964846722398}
\ No newline at end of file
+{"null": 1.7303640841198316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6962.json
index 1bcd13655b2..a2c80ebda4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6962.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6962.json
@@ -1 +1 @@
-{"null": 3.847134167320116}
\ No newline at end of file
+{"COSENTYX": 15.515135034892802, "null": 0.5868878430062934}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6963.json
index 192f913b985..37389cc2cd3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6963.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6963.json
@@ -1 +1 @@
-{"CELLCEPT": 19.34637327101921}
\ No newline at end of file
+{"null": 12.856326582999753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6964.json
index 1c0b1194fba..7042d67c792 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6964.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6964.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.84020242287921, "CICLOSPORIN": 12.181846287852244, "CIMZIA": 1.9310339455382732, "COSENTYX": 5.891223976755102, "ENTYVIO": 34.65867043786974, "HUMIRA": 6.2125717917968535, "JAKAVI": 6.272194798499495, "ROACTEMRA": 11.48707020822632, "SIMPONI": 6.170425806881032, "STELARA": 16.05297493890653, "SUTENT": 5.948989701493863, "VOTRIENT": 4.510479234840365}
\ No newline at end of file
+{"null": 3.3203043809919275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6965.json
index 28a18a42a17..21d62f65117 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6965.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6965.json
@@ -1 +1 @@
-{"CICLOSPORIN": 34.19241473878414, "null": 1.2510162039321255}
\ No newline at end of file
+{"COMIRNATY": 0.2284825962182305, "HUMALOG": 8.466070044186285, "OPTIMARK": 39.14153631062759, "null": 1.5608535217763104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6966.json
index 49e5ad2c745..cdb072789c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6966.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6966.json
@@ -1 +1 @@
-{"ASPARAGINASE": 56.19290957740202, "CYTARABINE": 44.54872015749093}
\ No newline at end of file
+{"null": 1.7537420309118223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6967.json
index d8f0b327f3f..ba14ed5c612 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6967.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6967.json
@@ -1 +1 @@
-{"null": 1.975350039634885}
\ No newline at end of file
+{"null": 3.5502334320668574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6968.json
index 60028a25aef..33bd9c640bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6968.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6968.json
@@ -1 +1 @@
-{"ABACAVIR": 1.063683321341727, "ACCOFIL": 1.2457166763756595, "ALIGN": 1.132909192729955, "AMBIRIX": 1.817251337790981, "AP": 2.48377731868219, "APEXXNAR": 2.457279491154506, "ATRIANCE": 3.738393341933047, "AUTOLOGOUS": 4.059378692465007, "BEXSERO": 3.79542759923243, "BINIMETINIB": 1.3908874152206807, "BLINCYTO": 1.657693215676129, "CEFTAZIDIME": 1.0295210875272864, "CERVARIX": 1.200191374684892, "CHLORHEXIDINE": 1.1173241314475806, "COBIMETINIB": 1.2548370909308555, "COMIRNATY": 1.9159872745903672, "COTELLIC": 1.3294227992555945, "COVID19": 4.326730597626697, "DABRAFENIB": 2.48585847194192, "DEXDOR": 1.2257502716034594, "DEXRAZOXANE": 1.7941356424992558, "DUKORAL": 1.1862779456295738, "EPCORITAMAB": 2.1740585214328405, "FASENRA": 1.0000734512841616, "FLEBOGAMMA": 2.18280722246917, "FLUCELVAX": 1.3534064772805603, "FORTIMEL": 3.4385160850659418, "GAZYVARO": 1.387352550471625, "HALAVEN": 1.0788875353327738, "HBVAXPRO": 1.5081397447260951, "HEXACIMA": 3.333429449267536, "HEXYON": 4.872707947582511, "INFANRIX": 4.547503932083949, "JCOVDEN": 1.2168986841575349, "KESIMPTA": 1.8016027733843871, "KIOVIG": 1.877814506811688, "KYMRIAH": 2.615402906920072, "LISOCABTAGENE": 3.739803912703095, "LITAK": 1.6454232423881394, "MABCAMPATH": 1.6560760471616505, "MEKINIST": 3.2013586110704533, "MENQUADFI": 4.403847995145165, "MENVEO": 1.9737796943594823, "MERCAPTOPURINE": 1.112613915233077, "MMRVAXPRO": 6.767609389863074, "NAGLAZYME": 1.8295644878405743, "NIMENRIX": 4.068086107794655, "NIVESTIM": 1.145437890245645, "NON": 2.3064283102326253, "NUSINERSEN": 1.0878814504506504, "PANDEMRIX": 1.19549405732587, "PEGFILGRASTIM": 1.4210996823133168, "PERJETA": 1.000631660517482, "POLIOMYELITIS": 2.2849047481931057, "PREVENAR": 3.4804902135149423, "PREZISTA": 1.034314103112132, "PRIVIGEN": 1.456575438500181, "PROQUAD": 3.7668342600306266, "QARZIBA": 3.125879337599676, "RADIATION": 1.0562965574862375, "REKAMBYS": 1.2641657534256534, "ROTARIX": 1.9496412465128257, "ROTASHIELD": 2.348532485624861, "ROTATEQ": 1.5431831462648016, "SHINGRIX": 1.7239403983869386, "SPIKEVAX": 2.677475144843428, "STIVARGA": 1.003008044209418, "SYNAGIS": 1.0583422428784806, "SYNFLORIX": 3.21711157386507, "TAFINLAR": 3.2417323990065148, "TOPOTECAN": 1.3062691387265697, "TWINRIX": 1.1365893387387358, "VAXZEVRIA": 4.145350589224831, "VIRAMUNE": 1.8664649805042928, "VYXEOS": 1.2153106891548795, "YESCARTA": 1.2831503660993566, "ZIAGEN": 2.447800505976079}
\ No newline at end of file
+{"null": 1.202010006444252}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6969.json
index 976eface428..8b15175417d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6969.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6969.json
@@ -1 +1 @@
-{"null": 2.7324561440655404}
\ No newline at end of file
+{"COMIRNATY": 0.6985726942095294, "SPIKEVAX": 0.6137385637919678, "VAXZEVRIA": 0.4242068892649165, "null": 1.195676110525418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/697.json
index a81be8ce782..ca59bd13ab0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/697.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/697.json
@@ -1 +1 @@
-{"VFEND": 54.06000265178909}
\ No newline at end of file
+{"RIXATHON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6970.json
index 42095799558..4fb51247dfe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6970.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6970.json
@@ -1 +1 @@
-{"null": 5.089377705412014}
\ No newline at end of file
+{"ATRIPLA": 1.0106564093462105, "CIMZIA": 5.206005370473124, "COMIRNATY": 0.1709947719485034, "HUMALOG": 2.0413698928486923, "LANTUS": 1.88973464822154, "OMALIZUMAB": 9.48128426103908, "SIMPONI": 2.763089859886355, "SUBOXONE": 3.63030183991497, "TRUVADA": 1.490403985729282, "XELJANZ": 7.580298427384784, "XOLAIR": 3.2013016684220634, "null": 1.5084720061578454}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6971.json
index 7a9c788c09a..8e978aafa12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6971.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6971.json
@@ -1 +1 @@
-{"CELECOXIB": 29.260658892586427, "CELLCEPT": 9.160431090205083, "FORXIGA": 11.562380839500122, "null": 1.3211650008794311}
\ No newline at end of file
+{"ABILIFY": 3.307190540085396, "APIXABAN": 3.6702008009573497, "BIKTARVY": 19.833474889458245, "CIMZIA": 1.4309345170361942, "COMIRNATY": 0.2174672041879276, "COSENTYX": 0.9592914000883684, "CYMBALTA": 0.7117276891385137, "ELIQUIS": 1.2410849708407032, "FAMPYRA": 8.953199418092316, "FORSTEO": 3.0017927295228373, "GARDASIL": 2.636477003373537, "HEMLIBRA": 20.438175479098213, "HUMIRA": 2.270291888064771, "IBRANCE": 1.3394692127044865, "KEPPRA": 0.9794426477064716, "LANTUS": 1.892392544893218, "LYRICA": 3.902849545761827, "METHOTREXATE": 2.169404214415728, "OMALIZUMAB": 7.911074769076015, "RITUXIMAB": 6.040097973690509, "SIMPONI": 2.274015410167851, "SPIKEVAX": 0.1463005748508922, "SUTENT": 0.3884126350491073, "TOZINAMERAN": 0.4867602963288614, "TRUVADA": 0.4744925132329497, "VAXZEVRIA": 0.236606078451789, "XELJANZ": 4.782557301351623, "XOLAIR": 3.8122382356983993, "ZOSTAVAX": 5.649129766930819, "null": 1.1587863835845462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6972.json
index 36eaa7cdaeb..0c267084d18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6972.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6972.json
@@ -1 +1 @@
-{"COVID19": 11.21102624713178, "TOZINAMERAN": 1.3343893459058096}
\ No newline at end of file
+{"COMIRNATY": 0.1983800803400933, "DARZALEX": 211.9208540814577, "DEXAMETHASONE": 42.95035094764254, "null": 0.4679488342317785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6973.json
index 8827bf0cb65..94171f97b92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6973.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6973.json
@@ -1 +1 @@
-{"null": 2.2755002640684667}
\ No newline at end of file
+{"CARFILZOMIB": 477.96203698013977, "null": 0.3298069902451951}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6974.json
index ce88aff3d7b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6974.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6974.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 4.793679542426659, "BUPRENORPHINE": 9.843175232473977, "CLOPIDOGREL": 4.073651944482668, "CYTARABINE": 4.3491671698186, "FENTANYL": 6.946663516619, "GARDASIL": 1.7010309434695736, "KEPPRA": 2.1766144077354044, "OLANZAPINE": 3.937688202581549, "TWINRIX": 16.515962612042877, "VAXZEVRIA": 1.2974223374735534, "null": 1.0636115083549431}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6975.json
index 4caddf50bab..3d50093e910 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6975.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6975.json
@@ -1 +1 @@
-{"CICLOSPORIN": 2.406121313082974, "CLOPIDOGREL": 3.2483733171611955, "DEXAMETHASONE": 4.816473021289911, "DOXORUBICIN": 18.82003183202208, "LEMTRADA": 7.709749894427327, "MIDAZOLAM": 12.419381586591715, "NAGLAZYME": 23.55633315203572, "PLAVIX": 1.8415964127274944, "null": 2.063711060751693}
\ No newline at end of file
+{"INVOKANA": 464.515703934641, "JARDIANCE": 35.10869124705385, "null": 0.3298069902451951}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6976.json
index 3ba674165d9..e1028225214 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6976.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6976.json
@@ -1 +1 @@
-{"AIMOVIG": 2.3884039981149265, "ANAKINRA": 9.834294971345996, "ATRIPLA": 13.160117790790572, "AZATHIOPRINE": 2.807755171683055, "CELECOXIB": 3.693080239636271, "CICLOSPORIN": 1.55855914079539, "CIMZIA": 2.4716785346551564, "ENTACAPONE": 10.613974978487114, "FENTANYL": 1.1799079619351227, "GARDASIL": 1.4089989880731169, "HYDROCORTISONE": 3.322878404175163, "LYRICA": 1.0833722127876366, "MEPOLIZUMAB": 1.7166462419117612, "METHOTREXATE": 1.375852590882496, "NUCALA": 7.694663577878702, "OMALIZUMAB": 2.653036056217251, "OPTIMARK": 10.337816255591784, "SOLIRIS": 1.1567773162415285, "STRIBILD": 8.731561370371342, "TRUVADA": 7.574126414369448, "VIREAD": 8.559122373653844, "VOTRIENT": 1.4162512075308988, "XOLAIR": 1.2236200745323924, "XTANDI": 1.6001516691830076, "ZOSTAVAX": 2.0274095443711047}
\ No newline at end of file
+{"null": 2.840171048211678}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6977.json
index 44ae8605db2..ebef45e6940 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6977.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6977.json
@@ -1 +1 @@
-{"BENLYSTA": 49.69031446954102, "NUCALA": 86.09840673239793}
\ No newline at end of file
+{"SUBOXONE": 19.797505479845285, "VAXZEVRIA": 0.3963401701104493, "null": 1.3269724487989134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6978.json
index 9cecd026769..70d62aba0d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6978.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6978.json
@@ -1 +1 @@
-{"null": 1.244470496613888}
\ No newline at end of file
+{"ADALIMUMAB": 4.802337983500555, "ARAVA": 8.839683254211137, "COMIRNATY": 0.1206081964363555, "ENBREL": 4.48556929796773, "HUMALOG": 2.250095462466253, "VAXZEVRIA": 0.1288474426895082, "null": 1.3983700097832892}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6979.json
index c568a2a9708..f2c07fd6f48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6979.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6979.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2054199313401912, "MIRABEGRON": 1483.774764809838}
\ No newline at end of file
+{"ABILIFY": 0.1309478055154785, "ADALIMUMAB": 0.1085650652327167, "AERIUS": 0.5148359552004098, "AFINITOR": 0.0908391797709703, "AIMOVIG": 0.2621566256954193, "ALEMTUZUMAB": 0.2666745822393354, "ANAKINRA": 0.2452465638578061, "APIDRA": 0.0771889099156867, "APIXABAN": 0.106637532463724, "ARANESP": 0.089208554967233, "ARAVA": 0.2239206836679941, "ARIPIPRAZOLE": 0.0658879135286279, "ATRIPLA": 0.0087760832825557, "AUBAGIO": 1.022277632617504, "BENLYSTA": 0.2988717396915107, "BETAFERON": 0.4762618581589088, "BEXSERO": 0.6238378901750283, "BIKTARVY": 0.2801326359504916, "BONVIVA": 0.3725740325287685, "BRINTELLIX": 0.271083790846944, "BYDUREON": 0.4435724047577469, "BYETTA": 0.2013114670604574, "CABOMETYX": 0.1139271909493808, "CHAMPIX": 0.0574952897893696, "CICLOSPORIN": 0.0706003546948143, "CIMZIA": 0.1101322074200016, "CLOPIDOGREL": 0.1599480189220945, "COAPROVEL": 0.2215990013300698, "COMIRNATY": 3.7525070729138665, "COSENTYX": 0.4678200267496127, "CYMBALTA": 0.1133929097117724, "DEXAMETHASONE": 0.0988382717310313, "ELIQUIS": 0.2828225576977664, "ENBREL": 0.3264355116937907, "ENTRESTO": 0.1580415505671401, "ENTYVIO": 0.2523528728599064, "EPIVIR": 0.3553251085737292, "EXFORGE": 0.5231362368241562, "FAMPYRA": 0.9001077169620023, "FASENRA": 0.3304737578822838, "FASLODEX": 0.3303802646162995, "FENTANYL": 0.053319253547864, "FIRDAPSE": 0.7669580357382711, "FORSTEO": 0.7983401910372097, "FORXIGA": 0.1231427761011714, "FULVESTRANT": 0.1938378118794896, "GALVUS": 0.2914052556713249, "GARDASIL": 0.4330654967609635, "HUMALOG": 0.3702925901504601, "HUMIRA": 0.0877625448179484, "HYDROCORTISONE": 0.4136576703016105, "IBRANCE": 0.3575014605982345, "IBUPROFEN": 0.3392043686944481, "INLYTA": 0.1715015182206584, "JARDIANCE": 0.1696006287260566, "JCOVDEN": 12.35007605688596, "KEPPRA": 0.0415897387184674, "KESIMPTA": 0.8700511160353087, "KEYTRUDA": 0.0404821683780906, "LANTUS": 0.2575668144570815, "LATUDA": 0.2236535152850897, "LEMTRADA": 0.3302427543257576, "LEVOFLOXACIN": 0.1575539143803242, "LIXIANA": 0.4387240014227788, "LYRICA": 0.4231562149098588, "MEKINIST": 0.1572673778744423, "MEPOLIZUMAB": 0.0897156564776456, "METHOTREXATE": 0.1105677617903441, "MICARDIS": 0.2051032742653874, "MMRVAXPRO": 0.1250475456308108, "MODERNA": 0.2150485783672777, "MULTAQ": 0.1958928918740394, "NEXAVAR": 0.1280303548288315, "NIMENRIX": 0.4533312197205969, "NUCALA": 0.1306019657828953, "OCRELIZUMAB": 0.9040557943970348, "OFEV": 0.1134711309273159, "OMALIZUMAB": 0.3608089717397949, "OPSUMIT": 0.1208404655459618, "OPTIMARK": 0.1572487523767115, "OXYBUTYNIN": 0.7096860271953179, "PEGASYS": 0.0489550411771046, "PEGINTRON": 0.0602409154811131, "PLAVIX": 0.0738724487919694, "PLEGRIDY": 0.563674198039925, "REVATIO": 0.2258006719974136, "RINVOQ": 0.3743467404261327, "SHINGRIX": 1.3286965990481503, "SIFROL": 0.3703382660657468, "SIMPONI": 0.0791337500970842, "SOLIRIS": 0.0620446007724098, "SPIKEVAX": 4.76640872556863, "SPRYCEL": 0.1076720851241944, "STELARA": 0.2202392853562118, "SUBOXONE": 0.0558411363308334, "SUTENT": 0.3115147987103071, "TASIGNA": 0.15538729844702, "TOZINAMERAN": 1.28903322298389, "TRULICITY": 0.1717533214272564, "TWINRIX": 0.2359185017063191, "VAXZEVRIA": 3.1457519871442714, "VIAGRA": 0.2403637414074146, "VOTRIENT": 0.1066037706252615, "XELJANZ": 0.5013049426572369, "XOLAIR": 0.2397414496253338, "XTANDI": 0.243731217411077, "ZOSTAVAX": 0.1209433063809374, "ZYPADHERA": 0.3346495689016213, "null": 0.1569877434298329}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/698.json
index 6e85e91ab14..28e06c4fc2a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/698.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/698.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 15.192759030826885, "AMIKACIN": 18.113661635648967, "ASPARAGINASE": 46.20120275181276, "AZACITIDINE": 10.788052278201825, "AZATHIOPRINE": 4.297640527661327, "BASILIXIMAB": 24.4099178951502, "BLINATUMOMAB": 42.72199471662792, "BORTEZOMIB": 6.431472475851303, "BUDESONIDE": 6.046332538424179, "BUSULFAN": 23.474763388473686, "CANCIDAS": 36.52320069456084, "CARMUSTINE": 17.246744755243064, "CASPOFUNGIN": 123.17096430585688, "CELLCEPT": 10.040600147633402, "CICLOSPORIN": 23.248633266444266, "CIMZIA": 1.3181174633783468, "CLADRIBINE": 23.802717880151977, "CLOFARABINE": 31.13863881843494, "CRESEMBA": 37.95264855299348, "CYTARABINE": 15.935425382432026, "DEXAMETHASONE": 10.402015594875046, "DOXORUBICIN": 5.890724589947423, "ESOMEPRAZOLE": 4.91561016242736, "GANCICLOVIR": 6.04004687555517, "HYDROCORTISONE": 5.765697820335313, "IBRUTINIB": 55.08954281720174, "JAKAVI": 4.388622574400241, "LEVOFLOXACIN": 2.240465102232472, "MEPOLIZUMAB": 5.681323653147612, "METHOTREXATE": 3.070950899119901, "MICAFUNGIN": 77.7193910044586, "MYCOPHENOLATE": 22.9935490410116, "NOXAFIL": 30.32686296215917, "OMALIZUMAB": 1.3267740160921446, "OPDIVO": 1.4262668994433956, "POSACONAZOLE": 30.36901757396796, "RITUXIMAB": 4.618573352950267, "ROACTEMRA": 3.691255643890668, "SOLIRIS": 3.883642484979247, "TACROLIMUS": 13.91952464524402, "TAMIFLU": 1.5444390594965158, "VFEND": 38.75906954946362, "VORICONAZOLE": 57.90992094083037, "XOLAIR": 1.2211064904199287, "YESCARTA": 5.149610333616589}
\ No newline at end of file
+{"null": 1.7361597874002588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6980.json
index 48ff787691b..63e2c39d39b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6980.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6980.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1058265513993917}
\ No newline at end of file
+{"ATRIPLA": 30.609643191425494, "TRUVADA": 17.986323589381943, "null": 0.2904340821737953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6981.json
index b2530a5e112..24ed4c71bda 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6981.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6981.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4277214534506, "null": 1.7525758659413262}
\ No newline at end of file
+{"null": 6.634517131311539}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6982.json
index 4314ffa2c64..2d19930f23d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6982.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6982.json
@@ -1 +1 @@
-{"null": 1.016791246989776}
\ No newline at end of file
+{"COMIRNATY": 1.515851738818219, "SPIKEVAX": 0.95125607006224, "TOZINAMERAN": 1.3892348862921795, "VAXZEVRIA": 2.254119158290001, "null": 0.3694677789746602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6983.json
index ce54362832d..ee8906c3fd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6983.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6983.json
@@ -1 +1 @@
-{"IBRANCE": 19.616821712125684, "KEYTRUDA": 6.785455178615529}
\ No newline at end of file
+{"ACLASTA": 12.253353225594433, "ADVATE": 20.54735479041749, "ALLERGY": 154.76060111989247, "APIDRA": 1.8460094852698496, "ARAVA": 0.2296550793268344, "ATRIPLA": 0.5465217826153193, "AUBAGIO": 1.2621245580089218, "BENLYSTA": 4.100039900216026, "BYDUREON": 1.7869755553004965, "BYETTA": 2.211694638895096, "CELLCEPT": 0.5741602259822981, "CHAMPIX": 0.5213487948754219, "CIMZIA": 0.5561683647873393, "CLOPIDOGREL": 0.6643403031902144, "COMIRNATY": 0.1993926012546081, "COSENTYX": 1.057621477727153, "CYMBALTA": 1.2482420191324235, "ELIQUIS": 3.266602749276509, "ENBREL": 0.7746456332019694, "ENTRESTO": 0.5112108193312719, "EVISTA": 1.5959157818365344, "FAMPYRA": 1.5733623643027377, "FENTANYL": 0.4481380328996407, "FORSTEO": 1.6566521964265195, "FORXIGA": 2.3164298695629157, "GALVUS": 2.7727102958813195, "GARDASIL": 0.4719351452554427, "HEMLIBRA": 8.90856941147081, "HUMALOG": 6.068243621239761, "HUMIRA": 2.464176862551832, "IBRANCE": 2.7438302884010595, "IBUPROFEN": 0.702292720394153, "ILARIS": 20.03756307875125, "INLYTA": 0.8956104650567244, "INSULIN": 2.1854326573313747, "JANUMET": 0.667338798481601, "JANUVIA": 1.1371834629557849, "JARDIANCE": 2.3910192634475296, "KEPPRA": 0.851727508328404, "KEYTRUDA": 0.3670791352299366, "KOVALTRY": 63.36811877106136, "LANTUS": 3.802869053852572, "LEVEMIR": 1.0354154893986696, "LEVOFLOXACIN": 0.6194804926202613, "LYRICA": 1.95041241143016, "MEPOLIZUMAB": 1.7831168315877035, "METHOTREXATE": 1.6762810726690478, "NEXAVAR": 0.718819758312065, "NUCALA": 1.6194692347999675, "OCRELIZUMAB": 1.0535665289898932, "OMALIZUMAB": 1.075100719611067, "OPSUMIT": 1.6833670013720463, "OPTIMARK": 0.6267823716481488, "PEGASYS": 0.4518975069491698, "PEGINTRON": 0.5462452808014158, "PLAVIX": 0.7306326033027807, "PREGABALIN": 1.2660747558790413, "REMICADE": 3.016224518745656, "REVATIO": 1.8982918491517704, "RINVOQ": 0.8065218514718235, "RITUXIMAB": 1.1306080715475657, "ROACTEMRA": 1.4385649431957528, "SHINGRIX": 0.6040167876156626, "SIMPONI": 1.7781040102966532, "SOMAVERT": 28.849978134739857, "SPIKEVAX": 0.2981434563822007, "STELARA": 1.2561204094438914, "SUBOXONE": 3.5475267648876327, "SUTENT": 3.076095651197522, "TAMIFLU": 0.8696422460425713, "TOVIAZ": 1.5694019315014829, "TOZINAMERAN": 1.118057292633959, "TRACLEER": 0.7464747838337156, "TRESIBA": 5.232721996930988, "TRULICITY": 1.1514371493250724, "TRUVADA": 0.497787586870354, "VAXZEVRIA": 0.575937631613869, "VELTASSA": 2.5276264457264697, "VIAGRA": 3.9514352262055614, "VICTOZA": 0.9259562759002748, "XELJANZ": 6.264294320204386, "XOLAIR": 0.7742468425871666, "XTANDI": 0.9567078117499352, "XYREM": 3.89101592731847, "ZOSTAVAX": 3.2699670487295585, "ZYPREXA": 0.4147492088436313, "null": 1.1299054513093598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6984.json
index 85b74d8d7c5..6ede1365b25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6984.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6984.json
@@ -1 +1 @@
-{"IPILIMUMAB": 112.07697226903947}
\ No newline at end of file
+{"ACLASTA": 62.08834775715734, "COMIRNATY": 0.798825257664897, "ELIQUIS": 2.7085831246852337, "FASLODEX": 4.802251280962516, "METHOTREXATE": 4.988630389992835, "OPTIMARK": 8.983798875109375, "PEGASYS": 2.6378063666562963, "SIMPONI": 7.874345015141874, "SPIKEVAX": 0.7236305700029353, "SUTENT": 1.130929201198904, "TOZINAMERAN": 3.260788540532149, "VAXZEVRIA": 0.6577731133808404, "XELJANZ": 3.5542456198730514, "null": 0.4936747686651412}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6985.json
index 68c5b11850a..5b9cbbaa473 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6985.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6985.json
@@ -1 +1 @@
-{"ADEMPAS": 54.69337486707991, "ALIMTA": 26.29113537833904, "IMFINZI": 1927.4831366743665, "IRESSA": 56.526177196016455, "KEYTRUDA": 32.071035686315774, "OPDIVO": 32.73041213859531}
\ No newline at end of file
+{"APIDRA": 5.10078810327346, "ARAVA": 2.578337883795712, "BENLYSTA": 9.882498156932748, "CIMZIA": 2.7372223375682108, "HIZENTRA": 7.888981930659752, "HUMIRA": 7.750100058322183, "IBRANCE": 1.6922348163965288, "LANTUS": 5.096501347730203, "SIMPONI": 23.238197067909848, "STELARA": 2.211241540140405, "SUTENT": 0.8965946082032444, "VAXZEVRIA": 0.0914228658951339, "VOTRIENT": 5.278391815847565, "XELJANZ": 7.806334022717994, "ZOSTAVAX": 2.223532267998189, "null": 1.1250831706389155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6986.json
index 793a2b5271f..5d49e591e05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6986.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6986.json
@@ -1 +1 @@
-{"ISENTRESS": 87.48984981283252}
\ No newline at end of file
+{"null": 4.370623298375501}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6987.json
index 6d59f091c1f..109ef79acb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6987.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6987.json
@@ -1 +1 @@
-{"null": 2.617674630797271}
\ No newline at end of file
+{"null": 0.8215158129056229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6988.json
index a08c778b8e1..199b22df798 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6988.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6988.json
@@ -1 +1 @@
-{"null": 3.8062365289207896}
\ No newline at end of file
+{"null": 7.116916263252886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6989.json
index 00e1efa8361..96c6479f0f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6989.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6989.json
@@ -1 +1 @@
-{"SPINRAZA": 83.89137901624666}
\ No newline at end of file
+{"SUBOXONE": 12.68299216640684, "null": 1.139652684078736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/699.json
index 64e4c9ecbec..cbc79a24783 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/699.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/699.json
@@ -1 +1 @@
-{"null": 1.659913266071359}
\ No newline at end of file
+{"ACLIDINIUM": 70.54966664321147, "ARANESP": 4857.137999716035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6990.json
index 9b8963e61bb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6990.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6990.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6030650245401687, "COVID19": 2.411832928514144, "TOZINAMERAN": 4.149864651049464}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6991.json
index 43ae743c76f..2ad6cc86fb5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6991.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6991.json
@@ -1 +1 @@
-{"ADALIMUMAB": 16.81527406706779, "ALIGN": 226.210064349624, "AMINOSALICYLIC": 123.76427984701807, "AVAMYS": 63.90543227694531, "BUDESONIDE": 92.01664958753116, "HYDROCORTISONE": 12.761698742674035, "IPILIMUMAB": 2.3856552349305784, "PREGABALIN": 35.53232718068973, "SHINGRIX": 1.185145029130963, "SUFENTANIL": 5.971469817310013, "TWINRIX": 4.7313983632975045, "ZOSTAVAX": 2.17258976451131}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6992.json
index 04f83c0802b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6992.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6992.json
@@ -1 +1 @@
-{"null": 2.119843710264686}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6993.json
index cc14e93679b..6dda058395a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6993.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6993.json
@@ -1 +1 @@
-{"BYDUREON": 10.687305041830118, "BYETTA": 13.138150580608652, "JANUMET": 29.39791720144687, "JANUVIA": 30.19286576594793, "KEYTRUDA": 21.86230494983322, "NEULASTA": 34.391378622403955, "PEMBROLIZUMAB": 31.937862675345663, "TRACLEER": 5.300263592362989, "VOTRIENT": 22.116721311726277}
\ No newline at end of file
+{"ABACAVIR": 8.50009195042409, "COMBIVIR": 26.47207259420638, "COMIRNATY": 0.2815303715061155, "PREGABALIN": 45.43554108321022, "SPIKEVAX": 0.3644840117788475, "SUTENT": 1.779311357942241, "TOZINAMERAN": 1.1863809217801706, "VAXZEVRIA": 0.2061252091002107, "null": 1.30458747470394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6994.json
index 028a0ef1345..2ae863fe2a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6994.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6994.json
@@ -1 +1 @@
-{"ATRIPLA": 21.679412632250795, "ENTRESTO": 4.409715182969413, "EVENITY": 101.206244799868, "EVISTA": 17.456502658096053, "FORSTEO": 5.2058989634648105, "NUCALA": 4.715258109487136, "STRIBILD": 5.277221955770337, "TRUVADA": 10.440973052944384}
\ No newline at end of file
+{"COMIRNATY": 0.2689542937766317, "RITUXIMAB": 17.197230871656547, "SPIKEVAX": 0.1824223629613444, "SUTENT": 2.245487520391824, "TOZINAMERAN": 1.34785918136101, "VAXZEVRIA": 0.2540134939043519, "null": 2.199649940067701}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6995.json
index 2450554c65b..ea93ca4b6da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6995.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6995.json
@@ -1 +1 @@
-{"AFINITOR": 2.577635253962545, "APIXABAN": 1.916778165120736, "ATAZANAVIR": 4.206955054090167, "BENRALIZUMAB": 97.69847076294988, "BIKTARVY": 6.495677077113978, "BUDESONIDE": 9.172967144451034, "BUPIVACAINE": 9.968013946641769, "CELLCEPT": 3.083760314087169, "CICLOSPORIN": 3.092285092940189, "CLOPIDOGREL": 4.227284391479579, "CUBICIN": 3.57432013906676, "ENTRESTO": 5.769772770862655, "ESBRIET": 2.6413737004021782, "EXJADE": 2.675232185901105, "FENTANYL": 1.4993642088154815, "INSULIN": 19.285108807716416, "IRBESARTAN": 4.144111679596472, "IVABRADINE": 30.680095877063952, "LEVOFLOXACIN": 1.675560540929016, "MEPOLIZUMAB": 21.582549911627225, "MICARDIS": 2.4997666088771604, "MYCOPHENOLATE": 3.842133121245576, "NUCALA": 2.9297755110967154, "OMALIZUMAB": 1.4375052971998878, "OPSUMIT": 1.6905634100085063, "ORKAMBI": 6.697439608737049, "PEGINTERFERON": 2.1896283999018222, "RIVAROXABAN": 15.35023473892008, "SPIRONOLACTONE": 6.71961083711728, "SYNAGIS": 3.298053290958874, "TRACLEER": 1.2682503893023371, "XOLAIR": 2.939297022574942, "null": 1.6194360427065608}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6996.json
index e100a72c0ff..39446000be3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6996.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6996.json
@@ -1 +1 @@
-{"SAMSCA": 5993.302475013472}
\ No newline at end of file
+{"ABACAVIR": 8.871796013938816, "AP": 2995.653479617848, "CLOPIDOGREL": 5.803738930470665, "FORTIMEL": 4132.516782492467, "LYRICA": 7.276537823834903, "PLAVIX": 3.27799375219679, "null": 2.5460413179383203}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6997.json
index 6bf63252ebb..3f315934f71 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6997.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6997.json
@@ -1 +1 @@
-{"null": 2.882650336471254}
\ No newline at end of file
+{"COMIRNATY": 0.6312378062016628, "SPIKEVAX": 0.2855337529833844, "TOZINAMERAN": 0.7825640122767609, "null": 2.4859112396151315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6998.json
index 7db78c21e72..3562efb8a0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6998.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6998.json
@@ -1 +1 @@
-{"null": 1.449437999465509}
\ No newline at end of file
+{"COMIRNATY": 0.2460439880701698, "SUTENT": 3.466216782892072, "null": 1.999958692758623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6999.json
index 8e0a79cf55e..a7c5a76b935 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6999.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/6999.json
@@ -1 +1 @@
-{"ABACAVIR": 2.771475918095327, "ABATACEPT": 1.4506518970731943, "ABRAXANE": 1.2054154918703908, "ADALIMUMAB": 1.0496559760152862, "ADENURIC": 2.000683397842741, "AFINITOR": 1.19355780332324, "ALIMTA": 1.8804679395800143, "ALPELISIB": 4.627759400842615, "AMBIRIX": 1.464674657556963, "ANTHRAQUINONE": 21.00269848737633, "ANTIHYPERTENSIVES": 2.092873464103183, "APALUTAMIDE": 5.321744298382776, "ARAVA": 1.965612817462945, "ARZERRA": 1.123831892661413, "AZTREONAM": 1.4003719996524908, "BETMIGA": 1.086755904128569, "BEXSERO": 2.2926588611246133, "BINOCRIT": 1.5511600404022936, "BOCEPREVIR": 1.2488845385371348, "BOSULIF": 1.5851705071706008, "BRAFTOVI": 1.1768277640584963, "BRIDION": 1.4852524950659045, "BRILIQUE": 1.0633532523100038, "BRUKINSA": 1.083059959156433, "CAELYX": 1.365040389528955, "CANCIDAS": 1.533988845949846, "CAPRELSA": 2.633323179765928, "CASPOFUNGIN": 1.0755286628823268, "CELSENTRI": 1.111690400765869, "CETUXIMAB": 2.977135524719828, "CHLORHEXIDINE": 3.5304294551831634, 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\ No newline at end of file
+{"CLOPIDOGREL": 6.954442404922289, "COMIRNATY": 0.2850321471707161, "VAXZEVRIA": 0.1955479457897834, "null": 1.381687522251324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7.json
index 5e4ca52288a..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7.json
@@ -1 +1 @@
-{"OPSUMIT": 58.94025901768779}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/70.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/70.json
index 7c4fdfbde97..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/70.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/70.json
@@ -1 +1 @@
-{"null": 2.2142953271576955}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/700.json
index 79660e9dc3a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/700.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/700.json
@@ -1 +1 @@
-{"ABILIFY": 1.6480741820709577, "ACTRAPID": 12.634981242525924, "ARIPIPRAZOLE": 2.117518661945191, "BUDESONIDE": 3.01882622423519, "BUPRENORPHINE": 12.84766290781818, "DARZALEX": 7.798539548111271, "ENTRESTO": 1.080028687818476, "EXFORGE": 4.232353464507827, "FENTANYL": 2.912225358882385, "INSULIN": 1.2997665668468343, "MEPOLIZUMAB": 3.860338665188433, "NUCALA": 2.0587769838947976, "OLANZAPINE": 2.4335233979392616, "OMALIZUMAB": 1.5783485903575416, "PREGABALIN": 2.83261731274444, "RELVAR": 6.067461207006208, "RISPERIDONE": 7.301962654714328, "ROTATEQ": 3.839890286940167, "SUBOXONE": 1.109340117503207, "SYNAGIS": 2.152085770439844, "TICAGRELOR": 37.63570374965063, "TOUJEO": 3.1347416653246403, "XOLAIR": 1.461223828318266, "ZYPREXA": 1.0916766214881577, "null": 3.394039828224976}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7000.json
index 797e7819945..5ee09ee6c20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7000.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7000.json
@@ -1 +1 @@
-{"ABACAVIR": 24.002935111778584, "ABASAGLAR": 1.0986366127439202, "ADENURIC": 1.468141291872286, "AERIUS": 1.411285773777134, "ALIMTA": 1.3129370793460986, "AMIKACIN": 2.219900181749688, "AZARGA": 26.19745515552989, "AZOPT": 23.076098587609238, "BEXSERO": 1.4401321373031946, "BUSULFAN": 1.4449740654745475, "CANCIDAS": 1.8508416737091071, "COTELLIC": 3.0379560305764066, "DESLORATADINE": 1.8142857587466592, "DEXAMETHASONE": 1.0695543192769417, "DIFICLIR": 3.358881854448865, "DUPIXENT": 1.3125811506520315, "ENBREL": 1.3314699346820558, "ENOXAPARIN": 1.3067120970543358, "ERLEADA": 4.299384290660118, "ESOMEPRAZOLE": 1.021156021502524, "FEBUXOSTAT": 1.1200049626080564, "FENTANYL": 1.3101075257903574, "HYDROCORTISONE": 1.3500825663040172, "IBUPROFEN": 1.1018523747119662, "ICLUSIG": 1.0092907929927202, "INCIVO": 2.3890673200387718, "KAFTRIO": 2.322508195490274, "LAMIVUDINE": 1.361865168237057, "LEMTRADA": 1.3359603187152538, "LEVETIRACETAM": 1.2444066896699977, "LEVOFLOXACIN": 2.997936605009793, "MEKINIST": 1.120398022860427, "MIDAZOLAM": 1.3911580158474748, "MMRVAXPRO": 4.232976187507645, "NAGLAZYME": 1.1899682893671448, "NEVIRAPINE": 2.9038120464215305, "NEXAVAR": 1.1330660883204302, "NIMENRIX": 2.01375609417544, "NOVONORM": 2.9568521690083385, "NUCALA": 2.306004017275608, "ORENCIA": 6.495387841387592, "PACLITAXEL": 1.1827269622125167, "PANTOPRAZOLE": 1.062815222655472, "PEGINTERFERON": 1.2077542845584064, "PREVENAR": 1.1031671998143422, "PRIVIGEN": 1.7228054403653086, "PROPRANOLOL": 1.3000670360441084, "PROTELOS": 2.204201313957307, "RENVELA": 15.011186979440405, "ROACTEMRA": 1.2691521274465938, "SHINGRIX": 2.058244239464839, "SPIKEVAX": 1.0508090835433168, "STIVARGA": 1.8431773706057657, "SUFENTANIL": 1.265000634983345, "TAMIFLU": 1.3876004779756994, "TEMODAL": 1.1788896478466804, "THALIDOMIDE": 1.4630767758265095, "TORISEL": 1.0015291265985724, "TOZINAMERAN": 1.3505757275367851, "VIRAMUNE": 2.342529101630762, "ZELBORAF": 2.127004733926385, "null": 1.7116717205230878}
\ No newline at end of file
+{"COMIRNATY": 0.1914752412883661, "GARDASIL": 5.0152810186693495, "HUMALOG": 3.5037420346326256, "KEPPRA": 3.40632505462118, "METHOTREXATE": 6.195029077388318, "SPIKEVAX": 0.5883147675295028, "SUTENT": 2.1784584380875445, "TOZINAMERAN": 1.0505895996780987, "null": 1.0502827878658234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7001.json
index 37689ad0577..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7001.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7001.json
@@ -1 +1 @@
-{"ADENURIC": 2.622158722603908, "AERIUS": 1.4740889412864802, "BENLYSTA": 1.1084349313422577, "BETAFERON": 2.0246893428786588, "BEXSERO": 3.6023462519664937, "BRILIQUE": 1.064672141967949, "CANCIDAS": 1.389282949198745, "CIRCADIN": 3.895195151923355, "COTELLIC": 3.698550424992341, "CUBICIN": 1.231127015484056, "ELIQUIS": 1.4648043112746336, "ENTYVIO": 1.153383980504899, "ERLEADA": 1.7164216454756729, "ESOMEPRAZOLE": 1.82418783389752, "FLEBOGAMMA": 2.8194846157169127, "INCIVO": 1.210784579307023, "INFANRIX": 3.2695746057557087, "IRBESARTAN": 1.051892063204233, "IRON": 2.133703944706537, "KAFTRIO": 3.2696538704262386, "KESIMPTA": 1.1969859086117731, "LEMTRADA": 1.758224382420096, "LIXIANA": 2.159497208530759, "MEKINIST": 1.3478078324632865, "MMRVAXPRO": 17.88957498348627, "NEXAVAR": 1.5617785421141617, "NIMENRIX": 2.9032586403137315, "NINLARO": 1.4893365531710234, "NORVIR": 2.1732448113742127, "OCALIVA": 1.5476024289168953, "OPTIMARK": 3.5487802114495945, "PANTOPRAZOLE": 1.238915489702989, "PLEGRIDY": 1.8930717595619948, "PREVENAR": 3.7838574689351647, "ROTATEQ": 1.1360842262044326, "SHINGRIX": 2.0877453918095847, "SKYRIZI": 1.9839262089497511, "SPIKEVAX": 1.0268251329044409, "STIVARGA": 1.3288955743870456, "SUTENT": 1.5595935727889876, "TOZINAMERAN": 1.4593504517333624, "VAXZEVRIA": 1.2262113442532652, "VIRAMUNE": 2.817503696732849, "ZIAGEN": 4.197702960892846, "null": 1.5340121493075505}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7002.json
index 5dcaea210af..d511bd3f0b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7002.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7002.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.702724383580082, "ADENURIC": 2.9882795692359645, "AERIUS": 3.801016806334382, "ALIMTA": 3.498597603812271, "ALPELISIB": 4.030981195593474, "AMIKACIN": 8.859653169574724, "APROVEL": 1.429471117452236, "ARANESP": 1.2089941549638477, "ARIXTRA": 17.28816975892597, "AZTREONAM": 3.864900755734383, "BEXSERO": 1.2318634841916625, "BIKTARVY": 1.2756407244478745, "BINOCRIT": 6.885778303271618, "BRIDION": 1.7057978474143338, "BRILIQUE": 4.692352370647558, "BUSILVEX": 2.386765216578421, "BUSULFAN": 1.6066516263952897, "CAELYX": 1.095493469548887, "CANCIDAS": 14.904908925870142, "CASPOFUNGIN": 9.530723214285532, "CELSENTRI": 5.948979686090576, "CIRCADIN": 5.624580362637078, "CLADRIBINE": 8.128794293862292, "CLOFARABINE": 3.293765757246716, "CLOPIDOGREL": 1.1210089204606144, "COAPROVEL": 3.5207018007645474, "COBIMETINIB": 18.162863555680005, "COMBIVIR": 2.9336086999229494, "COTELLIC": 18.955030211616936, "CUBICIN": 2.7879823127235825, "DAKLINZA": 1.1694796442221296, "DAPAGLIFLOZIN": 1.4627805180226392, "DAPTOMYCIN": 2.087681680463793, "DARUNAVIR": 1.5851154393975804, "DARZALEX": 1.2786793922599111, "DESLORATADINE": 2.8120161366622383, "DIFICLIR": 8.011337854444514, "EFAVIRENZ": 1.0377361441719812, "EFIENT": 1.3787988665334334, "EMEND": 3.9648273113514136, "EMTRIVA": 4.957008854912117, "ENOXAPARIN": 3.0293452941722783, "ENTECAVIR": 2.4812485812290936, "ERLEADA": 9.02704790942666, "ERTAPENEM": 7.599847646099263, "ESOMEPRAZOLE": 3.4752048904599184, "EUCREAS": 1.473387371862849, "FEBUXOSTAT": 2.8490280836336064, "FILGRASTIM": 1.4500582795885193, "FLEBOGAMMA": 1.2230701938900743, "FYCOMPA": 1.87288907293704, "GALVUS": 1.0782880913114568, "GEFITINIB": 1.4780889763446714, "IBRUTINIB": 3.65299281642972, "IBUPROFEN": 1.6708279281021206, "IMATINIB": 1.025335088603197, "IMNOVID": 4.417619662793072, "INCIVO": 5.180607521132699, "INFANRIX": 1.4150511209250902, "INTELENCE": 6.353346421745764, "INVANZ": 5.624801001344587, "IPILIMUMAB": 2.661380821192988, "ISENTRESS": 1.642506176757364, "KAFTRIO": 5.524423925826596, "KALETRA": 1.5005487403453974, "KEPPRA": 2.811049646804213, "KEYTRUDA": 1.2524252246604186, "KISQALI": 1.4099268103740978, "KIVEXA": 2.5458236966590846, "LAMIVUDINE": 2.3873286857142832, "LENALIDOMIDE": 3.298335783450171, "LEVETIRACETAM": 3.2324385088878818, "LEVOFLOXACIN": 2.2374429924409056, "LITAK": 72.23912974591937, "LOPINAVIR": 5.338574269806249, "LYRICA": 1.1373274609310964, "MABTHERA": 1.1799915277713309, "MEKINIST": 2.3701106085002603, "MICARDIS": 1.1299369291148698, "MIDAZOLAM": 2.5828295005712776, "MMRVAXPRO": 4.380605918029413, "NEVIRAPINE": 6.593499741032102, "NEXAVAR": 2.130480555193378, "NIMENRIX": 1.2352141307531646, "NIVOLUMAB": 3.2160327820643664, "NORVIR": 6.381747973221551, "NOVONORM": 3.134509368537787, "NOVORAPID": 1.0122808908953913, "NOXAFIL": 5.526468746979514, "ONCASPAR": 2.2438521141607817, "OPDIVO": 2.797687070726397, "OSELTAMIVIR": 2.6586810172186124, "PANITUMUMAB": 3.111255042219162, "PANTOPRAZOLE": 6.852038565926217, "PEGINTERFERON": 1.2469659789604906, "PEMBROLIZUMAB": 2.118334824169172, "POSACONAZOLE": 6.827515000791375, "PRADAXA": 1.140056361096953, "PREGABALIN": 1.0430253835632064, "PREVENAR": 2.4936435357451887, "PREZISTA": 8.311663762314943, "PRIVIGEN": 1.0501394737808734, "PROTELOS": 5.211904806447, "REVLIMID": 3.8767426990679006, "REYATAZ": 1.4153033083999145, "RIBAVIRIN": 1.6599431905293354, "RIXATHON": 2.174883727483841, "ROACTEMRA": 1.3743878446486972, "SORAFENIB": 2.776626436271433, "SPIRONOLACTONE": 1.731115582992975, "STIVARGA": 2.8064116937230037, "SUFENTANIL": 4.735983068484234, "SUSTIVA": 7.275481477147968, "TAMIFLU": 1.7355824009257363, "TEMODAL": 2.7870709919448804, "TEMOZOLOMIDE": 1.4290044067274807, "THALIDOMIDE": 3.2109750819015503, "TRIUMEQ": 1.7631371164833902, "VECTIBIX": 1.6593474491673998, "VEMURAFENIB": 4.550570885456634, "VFEND": 1.7780870617328568, "VIMPAT": 1.4473162524090195, "VIRAMUNE": 15.258290759774964, "VYXEOS": 10.775519792920134, "XARELTO": 1.8138676465066352, "YERVOY": 1.4362575443244745, "ZARZIO": 7.7295919859914495, "ZELBORAF": 6.218726989298431, "ZIAGEN": 9.857993925837802, "null": 3.311379679480457}
\ No newline at end of file
+{"null": 1.2888650102821348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7003.json
index f4e74958daa..a4a82c50fb3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7003.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7003.json
@@ -1 +1 @@
-{"null": 1.5276271081251525}
\ No newline at end of file
+{"ASPARAGINASE": 2.200092581512791, "AVAMYS": 0.8460404365372582, "BRIDION": 3.617056330707393, "BRILIQUE": 1.5241159535619964, "BRINTELLIX": 0.6326200626692317, "CHAMPIX": 0.3910800793827895, "CLOPIDOGREL": 0.5658353484592786, "COMIRNATY": 0.758061452728744, "COSENTYX": 0.3049848853648865, "COTELLIC": 4.096246433612609, "ELIQUIS": 0.2714753723256141, "ENTRESTO": 0.9837172046129078, "ESBRIET": 0.8611476929933348, "EXFORGE": 1.188142216429674, "EXJADE": 0.5271574849457576, "GARDASIL": 0.2381429212361911, "IBUPROFEN": 3.4133699219745286, "KEPPRA": 0.2748056098320909, "LEVOFLOXACIN": 2.898894592924168, "MICARDIS": 1.5122375598333455, "MIDAZOLAM": 2.5993907516435586, "MMRVAXPRO": 0.6277239890986415, "MODERNA": 1.4171067678221512, "OLYSIO": 3.1115354828713917, "ONCASPAR": 17.640166133587712, "PLAVIX": 0.3274080853067716, "RASILEZ": 2.67879431892859, "ROACTEMRA": 0.652085016193876, "SPIKEVAX": 0.3077463371777723, "SUTENT": 0.1090541110294531, "TAMIFLU": 0.7434760481636622, "TOZINAMERAN": 0.1418400214988039, "VAXZEVRIA": 0.3126269145576135, "XOLAIR": 0.8775911220714735, "null": 4.967816401061122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7004.json
index d1069f4842b..30adba7cc40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7004.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7004.json
@@ -1 +1 @@
-{"AERIUS": 2.220691224974386, "AMIKACIN": 2.793935905518331, "BEXSERO": 4.909259802355567, "CANCIDAS": 6.611616611287412, "COTELLIC": 3.659702749891444, "INFANRIX": 2.5648335564520037, "LIXIANA": 2.5655028597435705, "MMRVAXPRO": 223.28548270895348, "NIMENRIX": 3.5595553197714955, "PANTOPRAZOLE": 1.02839930986574, "PREVENAR": 10.694546844844876, "RIBAVIRIN": 1.7235242698772817, "SUFENTANIL": 4.77817246800226, "TAMIFLU": 3.810495463954853, "null": 2.308287413422828}
\ No newline at end of file
+{"COMIRNATY": 0.8469740589610826, "IBRANCE": 2.187747492887272, "SPIKEVAX": 0.508394875670523, "SUTENT": 2.8143267157688165, "TOZINAMERAN": 1.9855365419666853, "VAXZEVRIA": 0.6147160497427814, "null": 1.929521159982845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7005.json
index 344f7cd05dc..cc7194e9dac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7005.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7005.json
@@ -1 +1 @@
-{"null": 3.283619010401326}
\ No newline at end of file
+{"COMIRNATY": 2.092750994885318, "MEPOLIZUMAB": 18.57464567072249, "SPIKEVAX": 0.566892388890039, "TOZINAMERAN": 1.9005951019964444, "VAXZEVRIA": 0.4615915241961776, "null": 1.6196507721996014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7006.json
index 1fd26402e1f..9be63209b72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7006.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7006.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 1.2929273132527463, "AP": 167.12587408025297, "AZARGA": 109.99182813888548, "AZOPT": 69.24216472645077, "BIKTARVY": 1.7802302591660597, "CICLOSPORIN": 1.0464530407895691, "CONTRAST": 10.835913100096136, "COTELLIC": 6.08799769093459, "EFAVIRENZ": 2.0278031117796824, "EMEND": 13.289759670724608, "ERLEADA": 2.353534581936578, "EXFORGE": 1.1286220909389042, "FLEBOGAMMA": 2.0134069518047712, "INCIVO": 1.1380207596483745, "IPILIMUMAB": 1.2465717769484477, "KAFTRIO": 1.3333098893462394, "KALETRA": 1.440461618080359, "KEYTRUDA": 1.0384452148843004, "LAMIVUDINE": 1.4387151524011712, "MEKINIST": 1.0165862439429074, "MMRVAXPRO": 12.78169540931529, "NEXAVAR": 2.0587197190261666, "NIMENRIX": 2.8351242440122664, "OPDIVO": 1.3873953717397984, "OPTIMARK": 4.7982762713513845, "PEGASYS": 1.4010772274774943, "PEGINTERFERON": 1.279677047425279, "PREGABALIN": 1.0671785670531402, "PRIVIGEN": 1.1423601045391023, "RIBAVIRIN": 1.5183270837489988, "RINVOQ": 1.003385229511679, "ROACTEMRA": 1.0209207534176263, "SHINGRIX": 2.750786067681384, "SIFROL": 3.7677820191499465, "STIVARGA": 2.395909623620382, "TAMIFLU": 1.1614005687021938, "TWINRIX": 1.3168144976494338, "UROREC": 9.14669405834788, "VECTIBIX": 4.626204344969101, "VEMURAFENIB": 10.424398817434218, "VIRAMUNE": 3.7476867776574343, "XARELTO": 1.0446798117297584, "ZELBORAF": 2.3311874212651387, "null": 2.051002070621586}
\ No newline at end of file
+{"AERIUS": 0.8804710267346896, "AFINITOR": 0.8831725740746867, "AIMOVIG": 0.2904540298538308, "ANORO": 0.9859867767619068, "APIXABAN": 7.0458997018384, "ARANESP": 0.2780297789977877, "ARAVA": 0.051394160339627, "ASPARAGINASE": 0.689241799197163, "AUBAGIO": 0.2997034942295167, "AVAMYS": 0.2896716782067746, "BENLYSTA": 0.7065883943716247, "BETMIGA": 1.9975031381967143, "BEXSERO": 1.9441288509411023, "BRIDION": 1.7332918561735078, "BRILIQUE": 0.6903561329889898, "BRINTELLIX": 0.4567447596638905, "BUDESONIDE": 0.3095989267354321, "BYDUREON": 1.5615621792362668, "CELLCEPT": 0.1902915806235368, "CHAMPIX": 1.0156596678886916, "CICLOSPORIN": 0.1575179487098561, "CIMZIA": 0.4417660503280693, "CLOPIDOGREL": 0.6008030439867533, "COAPROVEL": 0.7818758899741165, "COMIRNATY": 0.8220539260647282, "COSENTYX": 0.7035456405504725, "CUBICIN": 0.8641020659053342, "CYMBALTA": 0.1815873648486445, "DESLORATADINE": 2.0016277528159945, "DEXAMETHASONE": 0.5702229334398644, "ELIQUIS": 0.4331087118316438, "ENBREL": 0.1843749741598063, "ENTRESTO": 4.290624792527113, "ENTYVIO": 0.5038343041348265, "ESBRIET": 0.5373262430316839, "EXFORGE": 1.3508195373406031, "EXJADE": 0.7044371933101966, "FASENRA": 1.3036270035621222, "FENTANYL": 0.8207740252682643, "FIASP": 1.6858502377076916, "FORSTEO": 0.3253165201109244, "FORXIGA": 0.4537627566234514, "GALVUS": 1.3997404432740506, "GARDASIL": 1.1191803842563264, "HIZENTRA": 1.0022855345082404, "HUMALOG": 0.1281662208065639, "HUMAN": 0.6206157971393659, "HYDROCORTISONE": 2.218696826873717, "IBRANCE": 0.1682710255623637, "IBUPROFEN": 0.6769758467064955, "IRBESARTAN": 2.364061046432881, "JANUMET": 0.2211732725698011, "JANUVIA": 0.5782702211021193, "JARDIANCE": 0.8172340370262209, "KEPPRA": 0.4460839942985433, "KEYTRUDA": 0.1763006805123352, "LANTUS": 0.3827612288827939, "LATUDA": 0.917852035378399, "LEVEMIR": 0.595538102772089, "LEVOFLOXACIN": 0.6388663995614948, "LYRICA": 0.5707188317186974, "MENVEO": 1.444401088672877, "METHOTREXATE": 0.2787175169184617, "MICARDIS": 1.3677196578993045, "MMRVAXPRO": 1.1856592447200374, "MODERNA": 0.2017437220552585, "NEULASTA": 0.8491502832821135, "NEXAVAR": 0.3155330754528083, "NIMENRIX": 1.9215251796778912, "NUCALA": 0.2025412734541656, "OCRELIZUMAB": 0.3907195183932665, "OLYSIO": 0.973163663811766, "OMALIZUMAB": 0.7864955350679981, "ONCASPAR": 9.786255334873264, "ONGLYZA": 1.6724382524659582, "OXYBUTYNIN": 2.819790701261078, "PANTOPRAZOLE": 0.6302413087334726, "PEGASYS": 0.2807295430183303, "PEGINTRON": 0.1030316778725317, "PLAVIX": 0.4371353612236527, "PRIVIGEN": 1.1143130479088426, "RASILEZ": 1.967109563890466, "RELVAR": 1.5228450126547788, "RINVOQ": 0.4610300478988137, "ROACTEMRA": 0.8325627632132498, "SHINGRIX": 0.8759591572709485, "SIMPONI": 0.1966558053910919, "SPIKEVAX": 0.8011710755857807, "STELARA": 0.4210100696560846, "SUBOXONE": 0.3687762687641547, "SUTENT": 0.2376377235862592, "TAMIFLU": 1.592841899782295, "TOUJEO": 1.126469028160505, "TOVIAZ": 2.364781242972004, "TOZINAMERAN": 2.177766145684913, "TRULICITY": 0.5353697589000194, "TWINRIX": 0.8144131123313284, "VAXZEVRIA": 1.0391885205921163, "VIAGRA": 0.3193329744714298, "XELJANZ": 0.2892812073923713, "XOLAIR": 4.2521425341931085, "XTANDI": 0.395697140630968, "ZELBORAF": 1.050202305508411, "ZOSTAVAX": 0.2824848149137489, "ZYPREXA": 0.0997535687103893, "null": 2.080203821335754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7007.json
index 46941ee24b2..f91483e1538 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7007.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7007.json
@@ -1 +1 @@
-{"null": 1.7097812275113782}
\ No newline at end of file
+{"AFINITOR": 4.308419573735097, "ARAVA": 3.5023443921986, "CIMZIA": 10.039787174782123, "COMIRNATY": 0.1918666292317048, "COSENTYX": 6.167152756255077, "FENTANYL": 5.348952480703394, "METHOTREXATE": 6.236465993299544, "SPIKEVAX": 0.1787162250046144, "VAXZEVRIA": 0.3014431765351923, "null": 1.024509581604209}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7008.json
index 487277dbaab..0d4606895cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7008.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7008.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.645049380968972, "AERIUS": 1.099052682258137, "ALIMTA": 1.772189770130102, "APREMILAST": 2.1632925714268985, "BETMIGA": 1.2645643009968444, "BOSULIF": 1.3544901382597392, "BRILIQUE": 1.3565455971216709, "BRINTELLIX": 1.2802569513153803, "CINACALCET": 3.009111845856291, "CIRCADIN": 1.345422484026704, "COMIRNATY": 1.1875487983395348, "COVID19": 1.0583164800417686, "CUBICIN": 1.641460205598605, "DARUNAVIR": 1.4219688396927417, "DESLORATADINE": 2.1994532012948205, "ELIQUIS": 1.018674927268164, "ENBREL": 2.874309927934957, "ENTYVIO": 1.1899030803342852, "ERLEADA": 9.094641264583297, "ESBRIET": 1.3775178814074158, "FASENRA": 2.409210588587377, "FEBUXOSTAT": 1.3491947327291314, "FLEBOGAMMA": 1.0971867747340651, "FORXIGA": 1.6820888042066544, "GEFITINIB": 2.988448749588748, "HYDROCORTISONE": 2.190773027960508, "IBUPROFEN": 1.196813369384749, "IMBRUVICA": 1.275128991260771, "INCIVO": 1.842409082386044, "INHIXA": 4.994023248744321, "INTELENCE": 3.1398908464701853, "INTERFERON": 2.303674630269364, "IPILIMUMAB": 1.0715796835736002, "KAFTRIO": 5.957822623776094, "KEYTRUDA": 1.0620752086549496, "KIOVIG": 1.2444792626457672, "KISQALI": 1.1442207114346905, "LAMIVUDINE": 1.0725124523407088, "LEMTRADA": 3.209032709943617, "LENALIDOMIDE": 2.6446630610189907, "LEVOFLOXACIN": 1.0934763656765325, "LIXIANA": 2.15863090811535, "LOPINAVIR": 2.489206781912797, "MAVENCLAD": 1.2723776437504142, "MIMPARA": 3.789961535698939, "MMRVAXPRO": 2.410353082935357, "MULTITRACE4": 198.8078758391397, "NIMENRIX": 1.2521003473004773, "NOXAFIL": 1.129286881737933, "ONCASPAR": 1.7689445927734588, "OPDIVO": 1.0979112728458271, "PEGASYS": 1.847314454462736, "PEGINTERFERON": 1.481701537265307, "PREVENAR": 1.256897498977432, "PRIVIGEN": 2.1022444291990205, "PROTELOS": 6.026591782276786, "RIXATHON": 1.7231179737779814, "ROACTEMRA": 1.1293600099097376, "SHINGRIX": 2.646759493432042, "SIRTURO": 3.546455720479756, "SPIKEVAX": 1.30393060117758, "TAGRISSO": 1.102919492850301, "TIVICAY": 1.0009725207508944, "TORISEL": 1.15890625515956, "TOZINAMERAN": 1.2183068752065545, "TWINRIX": 1.8330934579167524, "YERVOY": 1.687153206167363, "null": 1.3019045258390358}
\ No newline at end of file
+{"JANUVIA": 28.96956336952664, "JARDIANCE": 14.422679686767935, "null": 0.4289594792533348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7009.json
index 8a0b308480d..8909fd80d5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7009.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7009.json
@@ -1 +1 @@
-{"AERIUS": 5.554646601551784, "ALIMTA": 1.8862529632048692, "CHAMPIX": 1.5569145760866945, "COSENTYX": 1.0583920186661, "COTELLIC": 11.840390810471607, "ENTYVIO": 1.681912689920344, "ERBITUX": 10.305356744041344, "GEFITINIB": 14.735475412541208, "IBUPROFEN": 1.2966881996269377, "IRESSA": 6.458981539309405, "IRINOTECAN": 4.364527910255722, "KEPPRA": 1.1921614546779111, "LEVETIRACETAM": 1.1963107084225668, "LIXIANA": 4.269600279974583, "MEKINIST": 2.5146215323180927, "MMRVAXPRO": 1.3521884259168433, "NEXAVAR": 1.212912520334607, "OMALIZUMAB": 1.2140542540946166, "PANITUMUMAB": 38.03705630434703, "PANTOPRAZOLE": 4.145341114980701, "PEGASYS": 1.923322399199337, "RINVOQ": 5.641788329028064, "ROACTEMRA": 1.779098598273338, "SHINGRIX": 5.398692419341064, "SIMPONI": 1.5634754901082406, "STELARA": 3.182413094186707, "VECTIBIX": 45.27706100547796, "ZELBORAF": 6.526124254759968, "ZOSTAVAX": 1.0624439089776243, "null": 2.102040844081527}
\ No newline at end of file
+{"ABACAVIR": 0.5547465305965122, "ABILIFY": 1.5472231663044285, "ADCIRCA": 4.9118258206569845, "AMINOSALICYLIC": 1.7499755429267851, "ARAVA": 0.2557096479965636, "ASPARAGINASE": 7.399089291530031, "ATAZANAVIR": 1.969447655738368, "AUBAGIO": 1.8292093548806931, "AVANDIA": 0.5341074807833686, "BARACLUDE": 6.024164602347864, "BOSULIF": 4.18589047240673, "BRAFTOVI": 2.835657183522277, "BYDUREON": 5.048846553056928, "BYETTA": 10.136331236647957, "CABOMETYX": 1.8453747802819285, "CELLCEPT": 1.955607818833437, "CICLOSPORIN": 0.5729639690922335, "COMBIVIR": 3.386938801884705, "COMIRNATY": 0.068712914524521, "COSENTYX": 0.3519652472401705, "CRIXIVAN": 6.302456072497876, "CYMBALTA": 0.5292291327369647, "CYTARABINE": 1.6896177187750965, "DASATINIB": 26.601097506718855, "DEXAMETHASONE": 0.8284157422455212, "ELIQUIS": 0.4286969585490607, "ENTYVIO": 1.241946413971176, "EPIVIR": 9.724482354172173, "EUCREAS": 67.63168697118317, "EXJADE": 1.8235823809816083, "FORXIGA": 2.5157095298606813, "GALVUS": 26.767249508577606, "HARVONI": 1.4484302061349452, "HYDROCORTISONE": 2.4438800141232124, "ICLUSIG": 22.64525056272141, "INLYTA": 1.3877758081207965, "INOTUZUMAB": 81.7024835845914, "IPILIMUMAB": 4.333568386422847, "ISENTRESS": 4.406468561632863, "JAKAVI": 0.9675128816768348, "JANUMET": 17.03843321784514, "JANUVIA": 17.048021654068837, "JARDIANCE": 2.661130812369028, "KALETRA": 6.005976431710357, "KEPPRA": 1.3746717911366797, "KEYTRUDA": 2.2342813835973305, "LANTUS": 0.2168408980235765, "LYRICA": 0.6766900339590844, "MEKINIST": 3.8288939181089487, "MERCAPTOPURINE": 7.887355123575658, "MICARDIS": 1.2816305941228607, "NEXAVAR": 5.687153491700794, "NILOTINIB": 16.270825269823412, "OLANZAPINE": 0.6071770193372605, "ONCASPAR": 15.420887004898502, "OPDIVO": 3.2232245572285403, "PEGASYS": 0.298604349712083, "PEGINTRON": 0.5841912063253512, "PEMBROLIZUMAB": 1.4271968355213434, "RYBELSUS": 8.738680250910418, "SAXENDA": 15.057639001971657, "SCEMBLIX": 47.84433307375701, "SPIKEVAX": 0.0342392943392588, "SPRYCEL": 1.2655940237165528, "STIVARGA": 1.8718600709085924, "SUTENT": 1.3167913904506678, "TASIGNA": 32.00286633440593, "TRULICITY": 27.81706180731476, "VELMETIA": 39.6792820680849, "VFEND": 0.8362433109718242, "VICTOZA": 24.944896290529577, "VIREAD": 3.8011608575206366, "VOTRIENT": 2.7873366373119564, "XELJANZ": 0.2498340635956423, "ZIAGEN": 11.904355371471253, "ZOSTAVAX": 0.5450193193672759, "ZYPREXA": 2.1135296053248007, "null": 0.8667255386581717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/701.json
index 82f665531e0..1be9a230247 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/701.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/701.json
@@ -1 +1 @@
-{"ABILIFY": 1.9234948989369995, "ACLIDINIUM": 6.722209175374538, "APROVEL": 8.440866362445334, "ARANESP": 7.15716231469067, "BRIDION": 5.075995958779927, "BUDESONIDE": 16.01186398816886, "BUPRENORPHINE": 7.280313542139817, "COMTAN": 5.616510836806592, "ELIQUIS": 1.2515500709747769, "EMEND": 8.572635537133758, "FENTANYL": 1.9439479450480412, "FIRDAPSE": 4.75929026938899, "IBUPROFEN": 4.556899581465086, "KEPPRA": 3.2708359419541377, "LEVETIRACETAM": 2.954466996728858, "LYRICA": 1.856934435050456, "MIDAZOLAM": 12.898824435837671, "NUCALA": 4.9843300911235415, "OFEV": 1.6619062180819673, "OLANZAPINE": 4.270124471329763, "PLAVIX": 1.0221490872078516, "PREGABALIN": 4.669360870234154, "ROTATEQ": 1.9923850743015723, "SPINRAZA": 33.10227313430038, "STALEVO": 4.96983879617291, "SUBOXONE": 1.114339670799246, "SYNAGIS": 11.833684310483688, "TRACLEER": 1.4418529766708394, "TRELEGY": 2.744863917268729, "XTANDI": 1.8646386222761024, "ZYPREXA": 3.030996202754517, "null": 1.9364818571286877}
\ No newline at end of file
+{"null": 10.116306851841909}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7010.json
index e063b554fd6..4e1320f4f66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7010.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7010.json
@@ -1 +1 @@
-{"MMRVAXPRO": 506.8084816369881, "null": 1.0843303812522826}
\ No newline at end of file
+{"null": 1.093848453715495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7011.json
index fe76b627c6f..4c536d302e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7011.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7011.json
@@ -1 +1 @@
-{"null": 3.501729012920074}
\ No newline at end of file
+{"ABACAVIR": 10.272007388770064, "ATRIPLA": 1.881118391277592, "BIKTARVY": 57.20426184527183, "COMBIVIR": 24.880789245241147, "ZYPREXA": 8.691064027313393, "null": 0.7062017964757685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7012.json
index 7abd0e65270..0434ef4170c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7012.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7012.json
@@ -1 +1 @@
-{"APROVEL": 2.3163763357257543, "BRILIQUE": 1.0238387650085288, "DUPIXENT": 9.657588786118367, "INCIVO": 1.6969311343664524, "MMRVAXPRO": 26.97762269354571, "NEXAVAR": 1.0662225438844048, "NIMENRIX": 2.379259540249586, "RINVOQ": 1.0135203504507544, "ROACTEMRA": 1.7686910895740282, "SHINGRIX": 37.92686597504371, "STIVARGA": 1.6168382227848714, "ZOSTAVAX": 29.70981862553993, "null": 1.3993256250749753}
\ No newline at end of file
+{"ARAVA": 1.966902884431304, "CELSENTRI": 97.2135798576956, "CICLOSPORIN": 5.752773972339349, "DESCOVY": 106.53451714813713, "HUMALOG": 2.8732246046652703, "KALETRA": 14.103452350444083, "OLANZAPINE": 4.002647389762856, "RINVOQ": 24.463276362652337, "ROACTEMRA": 14.94715758314772, "UPADACITINIB": 105.97899889350984, "XELJANZ": 3.841197790319815, "ZYPREXA": 12.961412966144104, "null": 0.9243968311021978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7013.json
index b88075ebf91..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7013.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7013.json
@@ -1 +1 @@
-{"AIMOVIG": 10.593773639948637, "AUBAGIO": 1.6885864416409946, "BENLYSTA": 2.549651254156743, "BETAFERON": 6.364718809565585, "COMIRNATY": 1.186288823613391, "COVID19": 1.2681675601678672, "ERENUMAB": 55.37720285797511, "EXFORGE": 2.516973718853111, "FASLODEX": 1.9204298940718976, "GARDASIL": 3.866568026699421, "LEFLUNOMIDE": 6.078728777216509, "LYRICA": 2.0596882465307185, "METHOTREXATE": 1.152004674691152, "PEGASYS": 1.6765907003794738, "PEGINTRON": 2.2664341551497014, "REVATIO": 3.034748316644695, "SIMPONI": 1.4208039043633407, "TOZINAMERAN": 1.4089370268663997, "TRACLEER": 2.0397808543979017}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7014.json
index 139a8a9b8e2..fd2bfa00fd6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7014.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7014.json
@@ -1 +1 @@
-{"null": 3.487298748185552}
\ No newline at end of file
+{"ABACAVIR": 46.42425179826252, "APIDRA": 7.125144725168804, "ATAZANAVIR": 46.7551719328593, "ATRIPLA": 0.8126101950534094, "COMBIVIR": 18.59625241056286, "EPIVIR": 190.60670605547568, "HUMALOG": 7.627360713403401, "INDINAVIR": 131.48348004087248, "INSULIN": 23.656446569276422, "KALETRA": 10.604609818305931, "LAMIVUDINE": 43.77061911694503, "LANTUS": 2.372131640993974, "LEVEMIR": 21.880162054446537, "NOVORAPID": 28.79193052304979, "REYATAZ": 72.72424495166167, "STAVUDINE": 502.6771923047401, "null": 0.1690148662351829}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7015.json
index e5a28f6062f..cc18bc7334a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7015.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7015.json
@@ -1 +1 @@
-{"null": 3.0694156261115317}
\ No newline at end of file
+{"NINTEDANIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7016.json
index 629cb422efb..68195279948 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7016.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7016.json
@@ -1 +1 @@
-{"APIDRA": 3.455825536814637, "BRINTELLIX": 20.763838468148062, "CLOPIDOGREL": 3.678237880481062, "GREPID": 197.4792364666786, "HEXYON": 158.01937603946033, "INFANRIX": 16.409262317848658, "MMRVAXPRO": 26.152224523580703, "PREVENAR": 27.390414591103124, "TOZINAMERAN": 1.0170326227168718, "XELJANZ": 1.0649280974177244, "null": 2.8184379441578296}
\ No newline at end of file
+{"ABACAVIR": 65.03054498160915, "ABASAGLAR": 8.842062201004781, "ACTRAPID": 18.486994368373526, "AMPRENAVIR": 147.90997635781167, "APIDRA": 16.59811482947804, "APTIVUS": 313.1885069513086, "ATAZANAVIR": 61.81413290675173, "ATRIPLA": 1.5503742301967416, "BIKTARVY": 9.772942216336924, "COMBIVIR": 121.14353686676807, "CRIXIVAN": 118.34258518135223, "EFAVIRENZ": 56.82285513435125, "EMTRICITABINE": 17.559610123437768, "ENFUVIRTIDE": 155.41778268445293, "EPIVIR": 91.77322139930904, "FIASP": 9.92302377284063, "FORTOVASE": 94.48533793058571, "HUMALOG": 1.8945305396556649, "INDINAVIR": 138.6639156308147, "INSULIN": 5.906322113574764, "INTELENCE": 57.52824164423886, "INVIRASE": 107.48170491901207, "ISENTRESS": 43.93496327232247, "KALETRA": 20.463066708387498, "LAMIVUDINE": 23.014576515920773, "LANTUS": 6.803675171857742, "LEVEMIR": 10.2413143839419, "NEVIRAPINE": 30.515514340110848, "NORVIR": 51.442515404716, "NOVORAPID": 5.224998560588492, "REYATAZ": 45.35792210685551, "SAQUINAVIR": 540.0979097647316, "SEMGLEE": 373.8506342293514, "TIVICAY": 16.553652358115084, "TRIUMEQ": 12.824058483691358, "TRUVADA": 0.9108202320783824, "ZERIT": 129.77964585708622, "null": 0.0685981624458388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7017.json
index a81b0114c22..0ef020bf9b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7017.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7017.json
@@ -1 +1 @@
-{"null": 2.6556073102073143}
\ No newline at end of file
+{"ABACAVIR": 18.16045255675414, "COMIRNATY": 1.6611078265088324, "SPIKEVAX": 0.5639281138346924, "null": 0.5915542938034392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7018.json
index 61ddb51efa1..b9b7249ed4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7018.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7018.json
@@ -1 +1 @@
-{"null": 4.5426632883971685}
\ No newline at end of file
+{"null": 2.653709282728216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7019.json
index 45104be6e9b..401f5381478 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7019.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7019.json
@@ -1 +1 @@
-{"NEXAVAR": 74.97237136613865}
\ No newline at end of file
+{"ATAZANAVIR": 22.056573760384374, "ATRIPLA": 1.0345536346578657, "CICLOSPORIN": 3.2569422927231573, "CRIXIVAN": 41.87978178834146, "EFAVIRENZ": 34.48858109831706, "HUMALOG": 5.7232388522212485, "INSULIN": 17.41877711376577, "LANTUS": 6.9344427980709495, "LEVEMIR": 22.752987017699947, "MEPOLIZUMAB": 10.575965746572052, "NORVIR": 60.87722005330464, "NOVORAPID": 11.225440598911884, "null": 0.3640130007023976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/702.json
index aa83ed4002b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/702.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/702.json
@@ -1 +1 @@
-{"KALETRA": 1041.7043582125457}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7020.json
index 6d55750d5d7..95c3ba27f99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7020.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7020.json
@@ -1 +1 @@
-{"null": 2.739337169947462}
\ No newline at end of file
+{"COMIRNATY": 0.6666604643601234, "COSENTYX": 4.014777237076168, "ENBREL": 2.5075098067351163, "HUMALOG": 2.9311273266988853, "JANUMET": 5.1979374161485445, "JANUVIA": 5.697905834059018, "PEGASYS": 1.7210261364840247, "SPIKEVAX": 0.3547428073175467, "STELARA": 5.930555182123621, "TOZINAMERAN": 0.4953464845263476, "VAXZEVRIA": 0.2577880209102626, "XELJANZ": 1.761122772499495, "ZOSTAVAX": 4.35143865661858, "null": 0.942388493349984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7021.json
index 896c4995f20..c12d274b236 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7021.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7021.json
@@ -1 +1 @@
-{"GARDASIL": 3.653497583362144, "KEPPRA": 2.914259566032516, "LANTUS": 1.9686079084592816, "SUBOXONE": 10.204851545877334, "null": 2.3828843557912904}
\ No newline at end of file
+{"null": 1.308269228709178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7022.json
index cd3e5b2312f..81a5a06c12f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7022.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7022.json
@@ -1 +1 @@
-{"PANTOPRAZOLE": 201.99861287978104, "null": 1.9607734296071424}
\ No newline at end of file
+{"null": 1.1177434319171884}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7023.json
index 54f4c82cc78..6043f0ed060 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7023.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7023.json
@@ -1 +1 @@
-{"AIMOVIG": 3.0889517882026007, "ARIPIPRAZOLE": 5.1057221181270105, "CICLOSPORIN": 6.328287365571042, "EFAVIRENZ": 14.25731724137022, "METHOTREXATE": 6.54713590247154, "MIRVASO": 236.9391005386156, "OLANZAPINE": 6.256105129507945, "PLAVIX": 2.2488448511020303, "TENOFOVIR": 118.93981745434986, "null": 2.296025912237014}
\ No newline at end of file
+{"COMIRNATY": 0.6940597778015541, "null": 1.0117238947796094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7024.json
index 2a62a642c6d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7024.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7024.json
@@ -1 +1 @@
-{"null": 3.859879244102083}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7025.json
index 3ae73f9ea24..dc0d42fcf9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7025.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7025.json
@@ -1 +1 @@
-{"COSENTYX": 161.27938876942102}
\ No newline at end of file
+{"null": 0.5685029375035655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7026.json
index 9b7b2a32ae0..2580523a759 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7026.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7026.json
@@ -1 +1 @@
-{"OLANZAPINE": 106.88922511972568, "null": 1.162750327229765}
\ No newline at end of file
+{"ACTRAPHANE": 146.44913670522578, "APIDRA": 7.734987887301941, "FIASP": 420.3053508253225, "HIZENTRA": 4.495914957062828, "INSULATARD": 75.28688640571029, "LANTUS": 1.6431339188556486, "LEVEMIR": 9.254691516370343, "MIXTARD": 46.19583586412519, "MMRVAXPRO": 1.957457002966088, "NEVANAC": 251.35581652330288, "NOVORAPID": 387.9598312321807, "PROTAPHANE": 269.42646882059927, "SAXENDA": 9.349475343780858, "SIMPONI": 1.2479398493230882, "STELARA": 4.70902156774301, "TREMFYA": 11.520532976728912, "TRESIBA": 29.873395748988624, "VICTOZA": 4.150032216630228, "null": 0.6431189438361735}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7027.json
index 3526ea9feb0..f7be4ec590f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7027.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7027.json
@@ -1 +1 @@
-{"ALIMTA": 104.6420389196962, "CAPECITABINE": 50.37698390250745}
\ No newline at end of file
+{"null": 2.7373792987157866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7028.json
index 4d4b3d10692..b06cb7068ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7028.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7028.json
@@ -1 +1 @@
-{"VEKLURY": 59.5778111170493, "null": 57.33777439419582}
\ No newline at end of file
+{"LEMTRADA": 131.0666947238926, "null": 0.3294325221026783}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7029.json
index 61a94ff726a..b810b2f977d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7029.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7029.json
@@ -1 +1 @@
-{"CHAMPIX": 9.627420371106616, "HIZENTRA": 34.97980577250664, "IKERVIS": 223.1545420209044, "PRIVIGEN": 29.230659891431067, "VEKLURY": 83.27717717468008, "null": 8.231041966961813}
\ No newline at end of file
+{"CIMZIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/703.json
index f0e88be0d46..6aac0677c1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/703.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/703.json
@@ -1 +1 @@
-{"ELIQUIS": 7.614443614580375, "OPSUMIT": 24.128492591423804, "SPRYCEL": 197.14187567627616}
\ No newline at end of file
+{"EYLEA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7030.json
index 856ac3c97fa..ec96ec8e17c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7030.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7030.json
@@ -1 +1 @@
-{"CIMZIA": 18.384914281204043, "ENTYVIO": 16.549424687384747, "PEGASYS": 5.259920454766123, "STELARA": 36.27013395390577, "SUTENT": 2.927260241353654, "VOTRIENT": 12.622624450274008}
\ No newline at end of file
+{"ALEMTUZUMAB": 44.42212890935629, "AZATHIOPRINE": 24.789584777465944, "CICLOSPORIN": 6.393773971177988, "LEMTRADA": 79.27967180364159, "null": 0.5374061995627406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7031.json
index a60ccf22665..724d369b153 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7031.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7031.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 47.93257665093618, "STELARA": 12.30189522109119, "STIVARGA": 49.00619672516794}
\ No newline at end of file
+{"BRILIQUE": 1.6589582869475217, "CHAMPIX": 2.2563440532310266, "CLOPIDOGREL": 0.4884862066398507, "COMIRNATY": 0.9037378779379706, "CYMBALTA": 0.2948721993536398, "ELIQUIS": 1.7928619325726771, "ENTRESTO": 0.7065809419172289, "ENTYVIO": 1.584006693881378, "FORSTEO": 1.3521215445715729, "GARDASIL": 1.5635027673721729, "JARDIANCE": 0.4709666412601094, "KAFTRIO": 3.141675727639631, "KEPPRA": 1.433460979985436, "KESIMPTA": 4.753311765503098, "LANTUS": 0.5665757320589516, "LEVETIRACETAM": 1.1385150811812332, "MMRVAXPRO": 78.48819994934202, "NEXAVAR": 0.8085011010954909, "NIMENRIX": 9.401515346152744, "OFEV": 1.6696538114471262, "PEGASYS": 0.4185021126346456, "PEGINTRON": 0.5509565308808949, "PLEGRIDY": 3.3464724252192157, "ROACTEMRA": 1.193763688378035, "ROTATEQ": 4.227785841512978, "SHINGRIX": 1.2374266063444184, "SPIKEVAX": 0.6593858158145172, "SUTENT": 0.5990391881786018, "TOZINAMERAN": 0.1733063128743079, "TWINRIX": 5.788596026541258, "VAXZEVRIA": 0.6665104857731454, "XTANDI": 1.3882047122990828, "ZYPREXA": 0.72659760110452, "null": 1.055074476437052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7032.json
index 075fc6726a2..6fafe9305b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7032.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7032.json
@@ -1 +1 @@
-{"AVASTIN": 8.746797235302799, "BEVACIZUMAB": 6.517178790351814, "ELIQUIS": 3.4518961855279464, "HUMALOG": 2.052474809502654, "JAKAVI": 4.412952134802672, "JARDIANCE": 1.7363129382168847, "MEPOLIZUMAB": 8.737845000337044, "SIMPONI": 3.151996934427093, "SPRYCEL": 5.159626074196619, "STELARA": 10.4883039625451, "STIVARGA": 49.32310634570033, "VECTIBIX": 33.04762335678139, "XELJANZ": 1.6372416488330697, "null": 1.1752184416266416}
\ No newline at end of file
+{"KAFTRIO": 84.95371150424629, "null": 0.5107708972683702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7033.json
index fdaa6411a81..56549be61f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7033.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7033.json
@@ -1 +1 @@
-{"AVASTIN": 51.48815223798599, "STIVARGA": 113.54632127258456}
\ No newline at end of file
+{"GOLIMUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7034.json
index 4173689add8..acde332c10a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7034.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7034.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 21.2759915879959, "null": 1.385102020258557}
\ No newline at end of file
+{"ABACAVIR": 2.278848749431539, "ABATACEPT": 20.481010563554022, "ABILIFY": 7.833685051182968, "ADALIMUMAB": 6.873898683032275, "AMINOSALICYLIC": 1.5651007438254327, "ANESTHESIA": 139.48583358761417, "ANTIBIOTICS": 24.482197729375407, "APREMILAST": 28.497321730821493, "ARAVA": 6.834211130611148, "ATAZANAVIR": 6.584842355100015, "AZATHIOPRINE": 24.79731797007889, "BENLYSTA": 3.507425948673032, "BIKTARVY": 6.978214306370388, "BUDESONIDE": 0.8206440414959638, "BUPIVACAINE": 17.026650031659692, "BUPRENORPHINE": 0.9304599035623838, "CELSENTRI": 17.892309315246393, "CERTOLIZUMAB": 35.00823367625806, "COMBIVIR": 17.159039974943088, "COSENTYX": 0.6564775125861989, "DARUNAVIR": 10.052478716992622, "DEXAMETHASONE": 6.506330532717256, "DOLUTEGRAVIR": 10.904616724138082, "ECULIZUMAB": 48.0223760262891, "EFAVIRENZ": 6.079738640431882, "ELIQUIS": 0.2529447589071542, "EMTRICITABINE": 5.471324079702918, "ENOXAPARIN": 8.443148201903439, "EPIVIR": 6.587160846630346, "EPOETIN": 21.275077080012537, "FENTANYL": 12.97421602606081, "FONDAPARINUX": 196.14851672721463, "HYDROCORTISONE": 7.561978206375191, "INSULIN": 1.2243620314549442, "INVIRASE": 14.963944881939105, "IRON": 7.946739229432927, "ISENTRESS": 3.940831013802849, "KALETRA": 7.091758493291437, "KEPPRA": 0.5286790384814, "KIVEXA": 28.074936511916107, "LAMIVUDINE": 6.563415513755155, "LOPINAVIR": 20.221478650607683, "MAVENCLAD": 5.828086139353221, "NORVIR": 25.246827942120824, "OLANZAPINE": 1.0291435104097926, "REYATAZ": 17.04406533358518, "SUBOXONE": 0.8721036125998629, "null": 1.088224192196781}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7035.json
index 089e04c961b..fcf7ec19c46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7035.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7035.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.683919967036604, "ADEMPAS": 1.3597940927922827, "ALIGN": 39.60665694701842, "AMINOSALICYLIC": 20.57362400976395, "ARIXTRA": 6.291578025545048, "AVAMYS": 10.586676711272448, "AVASTIN": 4.698186352390009, "AZILECT": 2.3938827784808345, "BEVACIZUMAB": 2.9698872103896083, "BRAFTOVI": 2.3203354058294963, "BRILIQUE": 13.95423685329321, "BUDESONIDE": 12.827201639878952, "CHAMPIX": 1.2185351415815078, "CINACALCET": 4.418707178753816, "CLOPIDOGREL": 5.51232751021054, "COSENTYX": 1.1157178219649997, "DABIGATRAN": 11.599419205452095, "DASATINIB": 4.753150628198638, "DIFICLIR": 4.142357476857005, "DUOPLAVIN": 18.933622390184794, "EFIENT": 5.9834468760417, "ELIQUIS": 10.785926597124416, "ENOXAPARIN": 2.61199365365973, "ENTYVIO": 5.321300057264114, "EXJADE": 1.4844219013270248, "HUMIRA": 3.072863500269261, "IBUPROFEN": 1.477448392043303, "INCIVO": 4.506706422843994, "INFLECTRA": 6.27393944234994, "INFLIXIMAB": 17.368947854851182, "JEVTANA": 1.0042769281262751, "LIXIANA": 14.00433180472529, "LONSURF": 1.7181646826494577, "MVASI": 4.942017048857083, "NEXAVAR": 1.1855620991548794, "NPLATE": 1.0072872851203396, "OCTREOTIDE": 6.984364082233032, "OFEV": 1.3336790006568569, "PEGASYS": 1.5887974107334275, "PEGINTERFERON": 1.8201151168505052, "PLAVIX": 20.238873400085225, "PRADAXA": 21.964013991013093, "PRASUGREL": 11.713073360486606, "PREGABALIN": 6.642027657403015, "REMICADE": 1.7286481395947306, "ROACTEMRA": 1.1362755113845082, "ROTATEQ": 2.403234445151947, "RUCONEST": 1.646754243341796, "SPRYCEL": 1.3321284097515131, "STELARA": 1.0603630058157043, "STIVARGA": 1.8308355803710823, "SUTENT": 1.946432484957323, "TICAGRELOR": 4.633215208097326, "VELTASSA": 1.623090853833386, "VOTRIENT": 1.694569427916368, "XARELTO": 19.42164022474268, "XELJANZ": 3.4501137642808084, "YERVOY": 1.2154944990210983, "null": 1.2452307935675808}
\ No newline at end of file
+{"BOSULIF": 22.41480255799906, "CLOPIDOGREL": 1.5574723982207372, "COMIRNATY": 0.694580064305045, "FLEBOGAMMA": 24.941787286090964, "GARDASIL": 3.2144602592322165, "KIOVIG": 60.54969248978288, "MMRVAXPRO": 1.7551544301499105, "NAGLAZYME": 10.280916975096504, "OPTIMARK": 6.388184635194754, "PRIVIGEN": 19.031622473343152, "SPIKEVAX": 0.409544800448209, "TOZINAMERAN": 0.9697728994534512, "VAXZEVRIA": 1.084752432080078, "null": 1.3946725856050457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7036.json
index f0bae5b3826..8750208b9df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7036.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7036.json
@@ -1 +1 @@
-{"null": 3.162892144732844}
\ No newline at end of file
+{"AFINITOR": 2.9435361162506477, "AMIKACIN": 15.503320153638995, "ASPARAGINASE": 9.19155590411931, "AVASTIN": 5.3362209929513895, "BYETTA": 4.106544327383777, "CELLCEPT": 5.318817280864024, "CICLOSPORIN": 3.8393166891412056, "CIMZIA": 1.3477909171025475, "COMIRNATY": 0.0702693047165506, "COSENTYX": 2.0442765176381013, "CYTARABINE": 5.575072098749756, "DEXAMETHASONE": 2.8602752407581087, "ENTYVIO": 4.677537568749773, "JAKAVI": 4.379096068991414, "JARDIANCE": 1.952613692903915, "KEYTRUDA": 1.850036200762445, "LENVIMA": 13.400039871420544, "NEXAVAR": 10.125482308195616, "RINVOQ": 5.167140572681395, "ROACTEMRA": 8.000961867005916, "SUTENT": 1.988787658643795, "null": 0.9235696379927366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7037.json
index 2eaa598f27b..618fe3e91e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7037.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7037.json
@@ -1 +1 @@
-{"null": 1.53567740245871}
\ No newline at end of file
+{"LENVIMA": 271.07394042044467, "NEXAVAR": 297.61951492211045, "null": 0.1185559877941813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7038.json
index 6aae7ef1aeb..0e22fc54bf3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7038.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7038.json
@@ -1 +1 @@
-{"AVASTIN": 183.126423917505, "KEYTRUDA": 10.672991937282085}
\ No newline at end of file
+{"ABACAVIR": 0.886856681023779, "ABATACEPT": 1.3393278943713165, "ABILIFY": 0.6009714412746904, "ABRAXANE": 2.642989716356119, "ACTOS": 3.54714053290103, "ADALIMUMAB": 1.6969820287189512, "ADCIRCA": 3.237375237492586, "AFINITOR": 1.1348737411698515, "ALIMTA": 2.3133165310214348, "AMINOSALICYLIC": 1.8820875311590155, "APIDRA": 0.5544022456435072, "APREPITANT": 1.0927552817728328, "ARAVA": 1.1939029828877863, "ASPARAGINASE": 1.9241326289999523, "ATRIPLA": 0.2179858688618818, "AUBAGIO": 1.24375643077121, "AVANDIA": 0.9089565399732388, "AVASTIN": 1.231133807042222, "AXITINIB": 3.371965966341956, "AZATHIOPRINE": 0.5099873346110724, "BARACLUDE": 8.605807127052278, "BAVENCIO": 4.64996926001087, "BENLYSTA": 0.3157038048052427, "BETAFERON": 1.541124671731404, "BEVACIZUMAB": 1.0288859352192534, "BIKTARVY": 0.5259506196677506, "BINIMETINIB": 8.394019310031123, "BLINCYTO": 4.078308777820453, "BORTEZOMIB": 2.8775596145840594, "BOSULIF": 3.7584599413202393, "BOTULINUM": 1.1757141569906486, "BRAFTOVI": 4.004724307976833, "BRIDION": 0.9768598441722094, "BUSULFAN": 0.29863526349821, "BYDUREON": 0.336609127925657, "BYETTA": 0.4003853757033654, "CABOMETYX": 6.029553093943282, "CANCIDAS": 4.661810132107933, "CAPECITABINE": 1.7659797494577794, "CARFILZOMIB": 1.2061838771383686, "CELECOXIB": 1.486718053082482, "CELLCEPT": 1.3207141765137782, "CHAMPIX": 0.5143499178195843, "CICLOSPORIN": 1.0032727273690445, "CIMZIA": 0.5104903369440954, "CLOPIDOGREL": 0.6102922374318326, "COMBIVIR": 0.4564697782856227, "COMIRNATY": 0.0801022492572733, "COMTAN": 1.4723359401302716, "COSENTYX": 1.499063435373502, "COTELLIC": 1.436940168440707, "CUBICIN": 1.015879094566413, "CYMBALTA": 0.7324235846960114, "CYTARABINE": 0.5650848264002148, "DAKLINZA": 2.1047147619145083, "DARZALEX": 0.7029206314727846, "DEXAMETHASONE": 0.8273774235221496, "DOCETAXEL": 0.7192859593738616, "EDURANT": 7.24168984015721, "EFAVIRENZ": 0.8269351295878505, "EFIENT": 2.002261408379223, "ELIQUIS": 1.0570838915615783, "EMEND": 1.4751841880686496, "ENBREL": 4.618949909791152, "ENTRESTO": 0.3850328406164409, "ENTYVIO": 1.3876652646674494, "EPCLUSA": 2.227469251051033, "EPIVIR": 1.6686659168102806, "ERLEADA": 0.847650626758422, "ESBRIET": 0.4863793941134683, "ESMYA": 2.5057395282185007, "ESOMEPRAZOLE": 0.8917903978819209, "EVISTA": 0.9006904512404175, "EXFORGE": 1.09699548055979, "EXJADE": 4.537421315914231, "FAMPYRA": 0.5849607504653641, "FASLODEX": 1.4560917715632218, "FEBUXOSTAT": 6.650367268911463, "FENTANYL": 0.2849025132965916, "FORSTEO": 0.3306203761373546, "FORXIGA": 0.8795987486039608, "FULVESTRANT": 0.6776274462686596, "GALVUS": 1.7334258888347491, "GANCICLOVIR": 2.380944135646563, "GARDASIL": 0.1108979116428617, "GLIVEC": 2.751413058219708, "HALAVEN": 1.7022832695638312, "HARVONI": 1.399094178355062, "HEPSERA": 2.052152721024981, "HERCEPTIN": 0.6117749488637354, "HUMALOG": 1.1178562203603803, "HUMAN": 0.4961654443516159, "HUMIRA": 0.6615434623915233, "IBRANCE": 1.145561348712848, "IBUPROFEN": 1.1344757679332702, "ICLUSIG": 2.3031826408148737, "IMFINZI": 10.704866227543205, "INCIVO": 1.4404434807160411, "INLYTA": 1.959803153520072, "INSULIN": 0.7622278588957566, "IPILIMUMAB": 1.9115081421592848, "IRESSA": 12.835000063960898, "ISENTRESS": 3.510544703130953, "JAKAVI": 1.1809378751697428, "JANUMET": 0.690052091693761, "JANUVIA": 1.7994640123007957, "JARDIANCE": 0.3801562311259909, "KAFTRIO": 1.9940922577933524, "KALETRA": 1.3811851348379205, "KEPPRA": 0.798569981915087, "KEYTRUDA": 3.476965025956206, "KISQALI": 1.9825865896222543, "KYMRIAH": 0.7694343799251085, "KYPROLIS": 1.9454839609606047, "LACOSAMIDE": 0.7582189904466096, "LAMIVUDINE": 1.1209029017328909, "LANTUS": 0.9206311171370976, "LEFLUNOMIDE": 1.1250994164052988, "LENVIMA": 4.174418119128023, "LEVEMIR": 0.5785061177636535, "LEVETIRACETAM": 0.4639891498845295, "LEVOFLOXACIN": 1.4614870962621396, "LONSURF": 1.5061336906412708, "LYNPARZA": 1.2721804041668967, "LYRICA": 1.84650894976254, "MEKINIST": 2.675587149184285, "METHOTREXATE": 1.8915294539611216, "MICARDIS": 6.3990990878489695, "MIDAZOLAM": 0.4044820813228754, "MIRCERA": 1.1024200940083764, "MULTAQ": 1.3259093592694835, "MYCOPHENOLATE": 0.5290769163213946, "NEXAVAR": 4.91871587189219, "NIVOLUMAB": 3.7695818139304142, "NORVIR": 1.2340123395566758, "NOT": 1.7982439540780055, "NOVONORM": 1.578627704850836, "NOXAFIL": 1.48033085250778, "OCALIVA": 2.315184593772416, "OFEV": 2.3109187802046227, "OLANZAPINE": 0.5441771178038115, "ONCASPAR": 2.8780958641495054, "OPDIVO": 11.26697223504703, "OPSUMIT": 1.0317664917287084, "PAZOPANIB": 1.3094364914635066, "PEGASYS": 1.113516846320555, "PEGINTERFERON": 1.4716979445635925, "PEGINTRON": 1.2899112496186935, "PEMBROLIZUMAB": 0.5690287599039497, "PLAVIX": 1.8458576605000103, "PLEGRIDY": 0.9947437237799572, "POTELIGEO": 4.941759699053839, "RAPAMUNE": 1.6867676286022373, "REBETOL": 2.515200901213209, "REMDESIVIR": 2.718474235369021, "REMICADE": 1.625791428784628, "REVATIO": 1.11341483219222, "REVLIMID": 1.152506215019807, "REVOLADE": 5.854211892527528, "RIBAVIRIN": 1.3808603126284122, "RIBOCICLIB": 1.582642326720804, "RINVOQ": 1.4361051857911349, "RITUXIMAB": 0.5300096494957485, "ROACTEMRA": 0.8930986319829843, "SAMSCA": 4.238596509568318, "SAXENDA": 0.2926063607582354, "SIMPONI": 1.5180515584353993, "SOLIRIS": 0.7640351841848475, "SOTORASIB": 6.937692081216955, "SOVALDI": 1.1432877208122243, "SPIKEVAX": 0.0595917202584762, "SPRYCEL": 0.565650806624594, "STELARA": 0.3679640531264369, "STIVARGA": 6.031307863881112, "STRIBILD": 0.2444462336173505, "SUBOXONE": 0.9148539355146714, "SUTENT": 1.400253429632812, "TACROLIMUS": 1.4410897421089426, "TAGRISSO": 3.2453349166959704, "TAMIFLU": 5.3958315552922365, "TASIGNA": 2.63751722811759, "TEMODAL": 2.0097685927862594, "TOVIAZ": 0.6409569035893049, "TOZINAMERAN": 0.0820408822529321, "TRACLEER": 1.5881357893488832, "TREMFYA": 0.5847614254918548, "TRULICITY": 0.932239463113497, "TRUVADA": 0.3020799130601252, "TWINRIX": 0.5948688574592732, "VAXZEVRIA": 0.0274130538457758, "VEKLURY": 6.826580337098139, "VFEND": 7.066124976710237, "VIAGRA": 0.4047794888655914, "VICTOZA": 0.8836173530862996, "VIMPAT": 1.1878368438236775, "VORICONAZOLE": 1.9080377463071252, "VOTRIENT": 2.061150486334104, "XALKORI": 2.6982119486132814, "XARELTO": 1.5356888447870485, "XELJANZ": 1.339153067567386, "XELODA": 0.8439818384494492, "XOLAIR": 0.2596653148154226, "XTANDI": 0.550060449436021, "YERVOY": 2.1825646687641305, "ZOSTAVAX": 0.2138850373320731, "ZYPREXA": 1.0522447995746758, "null": 1.5413944073881842}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7039.json
index 07ef3eb4e73..95d54906558 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7039.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7039.json
@@ -1 +1 @@
-{"null": 5.378562024220134}
\ No newline at end of file
+{"null": 0.6110021031734242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/704.json
index 7909c3d0f8e..92d8a1898f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/704.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/704.json
@@ -1 +1 @@
-{"AVAMYS": 667.448664710335}
\ No newline at end of file
+{"BEOVU": 1357.3753331681553, "BROLUCIZUMAB": 379.5394755689658, "EYLEA": 220.4042150215594, "LEVOFLOXACIN": 4.330932645903101, "null": 1.4023470743617523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7040.json
index a055b05deec..57be140517d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7040.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7040.json
@@ -1 +1 @@
-{"ACLASTA": 225.0546184347296, "MIRABEGRON": 320.3578260631208, "null": 1.4057737919197093}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7041.json
index 0b9486a9fe3..f597b4cdf6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7041.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7041.json
@@ -1 +1 @@
-{"null": 1.9292257497652705}
\ No newline at end of file
+{"null": 0.2758322208109772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7042.json
index a902514bc04..ca437d16c8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7042.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7042.json
@@ -1 +1 @@
-{"ENTYVIO": 11.869816682032242, "INCIVO": 33.8738037951446, "LANTUS": 3.1312781005560457, "VEDOLIZUMAB": 167.032954129367, "null": 1.4314153730568575}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7043.json
index 3b355b5c71e..0f5ce65592d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7043.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7043.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 4.181403101425805, "PEGASYS": 1.9578516551790488, "SUTENT": 3.1452322596386515, "null": 1.411305856163049}
\ No newline at end of file
+{"ABACAVIR": 0.2052316138012513, "ABATACEPT": 6.234426444766801, "ABILIFY": 0.3331142102202144, "ACTOS": 4.948282474913838, "ADALIMUMAB": 8.729820800967543, "ALIMTA": 0.5874275684529364, "AMIKACIN": 1.2511962659013365, "AMINOSALICYLIC": 1.549650533097691, "ANAKINRA": 1.214065608224532, "APREMILAST": 5.634168981451155, "ARAVA": 6.35755018940815, "ARIXTRA": 3.9336780650627032, "ASPARAGINASE": 1.0371401946045842, "ATRIPLA": 0.1646745761930073, "AUBAGIO": 1.2180984792288396, "AVANDAMET": 1.5059451165366955, "AVANDIA": 1.9209611472494923, "AVASTIN": 0.8021810780892448, "AXITINIB": 2.781058730155713, "AZATHIOPRINE": 0.6562046882102295, "BARACLUDE": 3.5877528418912026, "BENLYSTA": 0.3468310583698589, "BEVACIZUMAB": 0.904911002789156, "BIKTARVY": 1.3867670845204323, "BOSULIF": 1.333314308886114, "BOTULINUM": 1.8124531987748564, "BUDESONIDE": 0.4095292662157603, "BUPRENORPHINE": 1.4022424809786564, "BUSULFAN": 1.0376385114694593, "CABOMETYX": 0.6951576432146923, "CAELYX": 1.6160313330802951, "CANCIDAS": 4.526709125891083, "CAPECITABINE": 2.112903462920692, "CASPOFUNGIN": 1.8144461330726904, "CELLCEPT": 0.5972930753366654, "CERTOLIZUMAB": 10.907271545275607, "CICLOSPORIN": 1.0286977766107246, "CIMZIA": 0.9935363210830372, "CLOPIDOGREL": 1.2128702998796117, "COMBIVIR": 0.6214569995222885, "COMIRNATY": 0.0388246340459001, "COSENTYX": 1.9214097489114537, "COTELLIC": 1.6690494557369393, "CUBICIN": 1.2058275060843904, "CYMBALTA": 0.5935036168062144, "CYTARABINE": 1.4080381757243132, "DAPAGLIFLOZIN": 4.863044443465836, "DEXAMETHASONE": 1.114385432440952, "DOCETAXEL": 1.703909401609809, "DOLUTEGRAVIR": 3.84765355622666, "DOXORUBICIN": 1.854547568785209, "EFAVIRENZ": 2.867689370019945, "ELIQUIS": 0.2717551125042082, "EMEND": 3.6608881760268086, "ENBREL": 0.3280194855837214, "ENOXAPARIN": 4.5245483211028885, "ENTRESTO": 0.5318061671133139, "ESOMEPRAZOLE": 1.8810748225537763, "EXFORGE": 0.7009058484442369, "EXJADE": 0.8296768240019822, "FASLODEX": 0.6707011307574883, "FEBUXOSTAT": 5.979765053244534, "FENTANYL": 0.3860399364149131, "FULVESTRANT": 1.251668588371854, "FYCOMPA": 3.229319690224901, "GEFITINIB": 5.327021095731904, "GLIBENCLAMIDE": 2.981297510437962, "HARVONI": 0.6789536147551714, "HERCEPTIN": 1.044708118625108, "HUMALOG": 0.2553075934477762, "HUMIRA": 0.3445582140348415, "HYDROCORTISONE": 0.8439548190840878, "IBRANCE": 0.6794538500425045, "IBUPROFEN": 3.157679125370897, "IRESSA": 1.5259568119454698, "ISENTRESS": 2.1311628834083733, "JANUMET": 0.6942282698863446, "JANUVIA": 0.2450270334269179, "JARDIANCE": 0.3544687936132185, "KALETRA": 1.652527047939384, "KEPPRA": 1.2916402728648189, "KEYTRUDA": 0.6670262943542842, "KINERET": 21.972363966381543, "KISQALI": 0.8871962425480183, "LAMIVUDINE": 5.951574222691468, "LANTUS": 0.0792742879067508, "LEVETIRACETAM": 1.620109984293745, "LEVOFLOXACIN": 3.2588790244893646, "LONSURF": 0.8617523422359791, "LOPINAVIR": 5.150873041398871, "METHOTREXATE": 1.5423847787036002, "MULTAQ": 3.457507176451214, "MYCOPHENOLATE": 1.144477494357388, "NEXAVAR": 0.8466073444387184, "NORVIR": 1.2811493954148827, "NOXAFIL": 5.327940108793181, "OFEV": 0.5586692143629625, "OLANZAPINE": 1.6587719309997364, "OPDIVO": 0.4155344225697119, "PACLITAXEL": 3.0279507347302164, "PANTOPRAZOLE": 1.2033331318748757, "PAZOPANIB": 3.2495188569297917, "PEGASYS": 0.3920002957410139, "PEMBROLIZUMAB": 1.2522586267093, "PEMETREXED": 2.278333507171818, "PLAVIX": 0.5316896230915049, "REBIF": 8.366328612052788, "REMICADE": 1.112038408762147, "RIBAVIRIN": 1.5706015332744443, "RIBOCICLIB": 2.180673050781036, "RITUXIMAB": 1.703246879740631, "SIRTURO": 12.052242875590746, "SPIKEVAX": 0.0400281541112972, "STELARA": 0.1471216034381026, "STIVARGA": 2.698425874431802, "STOCRIN": 11.968814558743084, "SUBOXONE": 0.4214563003741424, "SUTENT": 0.6395585704018053, "TAGRISSO": 0.7891823040821725, "TAMIFLU": 0.9046902319595276, "TASIGNA": 0.7254042732110889, "TEMODAL": 2.0615874713278037, "TEMOZOLOMIDE": 2.825557141379093, "TICAGRELOR": 1.3725366759575208, "TIGECYCLINE": 10.415109052940736, "TOZINAMERAN": 0.1505006717568783, "TRACLEER": 1.143704399010068, "TRUVADA": 0.2571533917706043, "VAXZEVRIA": 0.0319222731715615, "VFEND": 5.682750917640966, "VORICONAZOLE": 14.16604469093819, "VOTRIENT": 1.7976308245629615, "XALKORI": 2.6201608926682707, "XELJANZ": 0.6146119639176749, "XELODA": 2.1875435848493927, "ZYPREXA": 1.0510724836929486, "null": 1.5639909224857278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7044.json
index c17bde17a5e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7044.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7044.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 13.970288994597087, "ELIQUIS": 12.145510667586628}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7045.json
index 2f9a833c33b..84e3ea780b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7045.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7045.json
@@ -1 +1 @@
-{"ZOSTAVAX": 21.327620788775224}
\ No newline at end of file
+{"null": 1.1884035515330909}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7046.json
index 5cd63e377ac..7808192b434 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7046.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7046.json
@@ -1 +1 @@
-{"BRIDION": 7064.441157482105, "SUGAMMADEX": 1591.5272849619423}
\ No newline at end of file
+{"null": 3.212904785211645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7047.json
index 080a8a9bdf5..ca617b2d438 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7047.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7047.json
@@ -1 +1 @@
-{"AFINITOR": 6.722774516237736, "BUSULFAN": 12.887386691288976, "CAPECITABINE": 35.73464891570601, "CYTARABINE": 4.344231902568605, "FASLODEX": 12.052633135715649, "HERCEPTIN": 12.4395004226943, "IMATINIB": 26.689566410059797, "KEYTRUDA": 8.020456064420685, "LYNPARZA": 34.705306466483904, "MEKINIST": 14.22858399655825, "NEULASTA": 19.03528406823949, "RITUXIMAB": 10.24114600103334, "RUBRACA": 42.9710601906414, "TAGRISSO": 10.40935008333442, "TEMODAL": 24.556628805135485, "TEMOZOLOMIDE": 27.349213887157944, "VOTRIENT": 7.1166075887003535}
\ No newline at end of file
+{"null": 0.6962929566312785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7048.json
index 63426e4fcf2..c278d60d887 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7048.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7048.json
@@ -1 +1 @@
-{"ADENURIC": 75.9988236208984, "ARANESP": 8.72464495417338, "CICLOSPORIN": 5.920040566231614, "COMBIVIR": 24.448978223515923, "PEGASYS": 6.155601416996599, "SUTENT": 2.321133591053897, "null": 1.0972186888504585}
\ No newline at end of file
+{"JANSSEN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7049.json
index bc34b549a23..c04ab1bce89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7049.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7049.json
@@ -1 +1 @@
-{"null": 1.2723219839493107}
\ No newline at end of file
+{"PEGASYS": 4.323495871313302, "null": 1.04278952192889}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/705.json
index 1fc458bf179..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/705.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/705.json
@@ -1 +1 @@
-{"MEPOLIZUMAB": 184.3753193869933, "null": 1.99321033143221}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7050.json
index 78c9aaad84b..6c4c208291d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7050.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7050.json
@@ -1 +1 @@
-{"IBRANCE": 14.157582683321062, "KEYTRUDA": 3.739268058052948, "PEGASYS": 3.7122073522632566}
\ No newline at end of file
+{"BARACLUDE": 43.0860132100201, "CICLOSPORIN": 2.6400429866606534, "DACLATASVIR": 131.16569623171617, "DAKLINZA": 50.61370761165082, "EPCLUSA": 57.531365047012585, "HARVONI": 40.72665666149275, "INCIVO": 19.206452201029723, "KAFTRIO": 14.717770180382423, "LANTUS": 2.5500124648543774, "OCALIVA": 62.27696103920935, "OLYSIO": 19.22634199254209, "OPSUMIT": 12.581606206670688, "PEGASYS": 2.4687698225527845, "PEGINTERFERON": 9.091632786840236, "PEGINTRON": 6.172533444558133, "RAPAMUNE": 18.495881322647573, "RIBAVIRIN": 23.68568270437797, "null": 0.9973091298787464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7051.json
index 3fe91d8a13c..4711e9e44a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7051.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7051.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.066948652430748, "ADENURIC": 3.826591863159615, "AFINITOR": 2.3739848693195924, "ALIMTA": 1.7153356594958793, "AMINOSALICYLIC": 2.3403199476624468, "ARANESP": 1.6624013684817442, "ARIPIPRAZOLE": 2.6930901219451564, "AVASTIN": 1.282899389970451, "BEDAQUILINE": 1.752064600144597, "BEVACIZUMAB": 2.50550337315122, "BLINCYTO": 12.054738877525292, "BOCEPREVIR": 4.92110523420947, "BOSULIF": 2.492275087211099, "BRILIQUE": 1.7351129848566291, "CAPECITABINE": 1.8981780402628132, "CLOPIDOGREL": 1.354460612245577, "COMBIVIR": 1.4086370586306665, "COMTAN": 2.3194771085177304, "DARZALEX": 1.3475949172818575, "DEXAMETHASONE": 1.308255279644878, "DOCETAXEL": 1.820612073403232, "DOXORUBICIN": 3.606995105170477, "ELIQUIS": 1.1727370932502237, "ENTRESTO": 1.752081784804584, "EXJADE": 5.257653590865671, "FASLODEX": 4.756909203148442, "FORSTEO": 1.175181492104447, "FULVESTRANT": 4.046474150677802, "GANCICLOVIR": 1.9321533301976503, "GLIVEC": 2.623605299030118, "HALAVEN": 2.330319721118961, "HERCEPTIN": 2.6331414665676496, "HYCAMTIN": 59.5453019001828, "IBRANCE": 16.87773232875127, "ICLUSIG": 2.3439505318834817, "INCIVO": 1.19522186726591, "INFERGEN": 16.823621327997, "INTELENCE": 6.131405407137554, "JAKAVI": 6.557492891615762, "KISQALI": 2.487172250706836, "KYMRIAH": 5.592592327324308, "LEMTRADA": 3.370313038324932, "LONSURF": 8.974819528740571, "LYNPARZA": 5.516407801376233, "MABTHERA": 1.8703111315133645, "MEPOLIZUMAB": 1.147999765987761, "METFORMIN": 7.5991257544354385, "METHOTREXATE": 1.2431004639938383, "NEULASTA": 2.408527315012829, "NINLARO": 2.693605988565964, "OLAPARIB": 5.361850044180246, "OPSUMIT": 1.6911389217818305, "OZEMPIC": 7.238290842553463, "PEGASYS": 19.262463026304136, "PEGINTERFERON": 2.1769398448989614, "PEGINTRON": 7.588078949916194, "PEMETREXED": 1.969032523216012, "PLAVIX": 1.8611735108916223, "PRADAXA": 3.816201780561157, "RASILEZ": 1.8018691426527444, "REVLIMID": 3.9342605766055656, "RIBAVIRIN": 2.548765900302668, "RUBRACA": 18.509743577598037, "RUXOLITINIB": 6.181037183481511, "SOLIRIS": 3.365340548700763, "SPRYCEL": 3.0586655438707, "SUTENT": 3.086846578551244, "TASIGNA": 1.4095981184476312, "TEGAFUR": 15.814446673867652, "TOPOTECAN": 8.22848145155893, "XARELTO": 1.0121288246694375, "XELJANZ": 1.5036638271154166, "XOFIGO": 3.6771648295936767, "ZIAGEN": 5.033734481746527, "ZOMETA": 4.146037488744774, "ZYPREXA": 1.0291824052457803, "null": 1.035686474448012}
\ No newline at end of file
+{"PEGINTERFERON": 216.20921605597152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7052.json
index cd0730dbbc9..7bb201db19e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7052.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7052.json
@@ -1 +1 @@
-{"BEDAQUILINE": 15.872177732558368, "JAKAVI": 21.947840768986847, "JARDIANCE": 3.4860689827184874, "KEYTRUDA": 2.200138244218991, "MEPOLIZUMAB": 9.152397548808349, "OLANZAPINE": 3.3472621968584666, "PEGASYS": 2.1716365869484715, "SUTENT": 1.081658777122024}
\ No newline at end of file
+{"AZATHIOPRINE": 15.42334531083933, "BASILIXIMAB": 49.61194538204336, "CELLCEPT": 29.49269589739478, "CICLOSPORIN": 78.06139161976958, "MYCOPHENOLATE": 37.03336670706999, "PEGASYS": 3.294369690463115, "PEGINTERFERON": 13.699027567553191, "PEGINTRON": 6.073202179948938, "RAPAMUNE": 63.5703406826392, "RIBAVIRIN": 12.654757578857504, "SIROLIMUS": 340.61135450972023, "TACROLIMUS": 108.23083641779152, "null": 0.3946433305978376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7053.json
index 51a3d619e05..3491cb4bf8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7053.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7053.json
@@ -1 +1 @@
-{"PEGASYS": 20.63941900416405}
\ No newline at end of file
+{"VICTOZA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7054.json
index 27651c1749d..ec0fc0eff06 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7054.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7054.json
@@ -1 +1 @@
-{"CICLOSPORIN": 80.64849201795718, "SOLIRIS": 57.98788632389085}
\ No newline at end of file
+{"COMIRNATY": 1.2335752058024938, "FORSTEO": 14.421763753569222, "SPIKEVAX": 0.2751327824956427, "VAXZEVRIA": 0.6859232637376549, "null": 0.9789386374701085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7055.json
index 2783bebb92d..b73b077b572 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7055.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7055.json
@@ -1 +1 @@
-{"ABATACEPT": 30.053492596664142, "ADALIMUMAB": 14.775003261985889, "APREMILAST": 447.2689026325131}
\ No newline at end of file
+{"RISPERIDONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7056.json
index e624a21541e..53f88d575b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7056.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7056.json
@@ -1 +1 @@
-{"ABATACEPT": 11.234574149417629, "ACLASTA": 62.00997749526741, "ADALIMUMAB": 13.83199416613156, "ANAKINRA": 162.28748150609337, "APREMILAST": 5.828459560207387, "ARAVA": 21.83408710047699, "AZATHIOPRINE": 21.619128731854133, "CELLCEPT": 3.028318415208844, "CERTOLIZUMAB": 73.63894661296554, "CICLOSPORIN": 4.0826164131228655, "CIMZIA": 5.548832658261476, "COSENTYX": 5.642331779471181, "ENBREL": 45.7937823890589}
\ No newline at end of file
+{"VOTRIENT": 21.713913861893857, "null": 1.9496264162926595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7057.json
index 71f00f45cfe..0d2ac78bc1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7057.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7057.json
@@ -1 +1 @@
-{"ANAKINRA": 73.31830171228482, "CARIPRAZINE": 2121.8609380328053, "HUMIRA": 39.534305112580185}
\ No newline at end of file
+{"null": 1.80462367809423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7058.json
index 05ea9c6533a..2119e4460fd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7058.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7058.json
@@ -1 +1 @@
-{"ABATACEPT": 5.46967153602994, "ADALIMUMAB": 4.041460858897409, "AMIKACIN": 3.918920902624868, "ANAKINRA": 57.61749784620742, "APREMILAST": 6.650550715651783, "ARAVA": 5.355280711869139, "AZATHIOPRINE": 3.5424117679233014, "BUDESONIDE": 1.863181833526951, "CICLOSPORIN": 4.484392485965304, "CIMZIA": 1.8423387935680149, "COAPROVEL": 2.4363626137069585, "COMBIVIR": 1.9893679870621264, "COMTAN": 11.715200002693567, "COSENTYX": 3.836412460617568, "ENBREL": 26.98275355078131, "ENTRESTO": 1.190245770417906, "ENTYVIO": 1.7789475235718215, "EXFORGE": 2.223274593071863, "HUMIRA": 9.640759914309262, "LEFLUNOMIDE": 12.469854878167524, "METHOTREXATE": 3.392075425820736, "OLANZAPINE": 1.0502259295795895, "RINVOQ": 2.4447904677894483, "RITUXIMAB": 1.3648301694256688, "ROACTEMRA": 1.374718814924944, "SIMPONI": 2.2641024436007475, "TELMISARTAN": 9.898958802959395, "XELJANZ": 7.057728448592082, "XOLAIR": 1.0126776447584818}
\ No newline at end of file
+{"COMIRNATY": 1.3085970266740783, "null": 1.191905231702337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7059.json
index b0bd01a8670..269e5d9eaf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7059.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7059.json
@@ -1 +1 @@
-{"PRIVIGEN": 457.6094814714768, "null": 1.1422246581022015}
\ No newline at end of file
+{"BUPIVACAINE": 595.2238377440383, "null": 3.060285166340289}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/706.json
index 906ff5503d8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/706.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/706.json
@@ -1 +1 @@
-{"null": 4.007036161400551}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7060.json
index 6756b0c506a..20894c520e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7060.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7060.json
@@ -1 +1 @@
-{"ELIQUIS": 29.079301342660955, "KEYTRUDA": 4.160238052556816, "OPSUMIT": 26.234829395404983, "PEGASYS": 2.3889335889434657, "PEGINTERFERON": 11.510305786449738, "PEGINTRON": 4.520038591047882, "SOLIRIS": 24.26143917712872, "TRACLEER": 16.84039354442232}
\ No newline at end of file
+{"APIDRA": 0.9546184018072766, "COMIRNATY": 2.3105067626320275, "GARDASIL": 1.7299658277684475, "HIZENTRA": 1.8301955661376912, "HUMIRA": 1.7421450970798995, "MENVEO": 25.032541326903686, "MMRVAXPRO": 2.94402812755673, "MODERNA": 2.012589058948204, "NIMENRIX": 6.358764998789755, "PLEGRIDY": 1.9600228110448408, "PREVENAR": 4.131964970962158, "ROACTEMRA": 1.366438661357083, "SHINGRIX": 18.186827113880906, "SPIKEVAX": 3.332324887716945, "TOZINAMERAN": 1.211474881100779, "TWINRIX": 6.713910802309224, "VAXZEVRIA": 2.527936154737739, "XOLAIR": 1.1932252081728738, "ZOSTAVAX": 0.5667225946369329, "null": 0.4581064772518196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7061.json
index b5adbadd495..fda2c848f4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7061.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7061.json
@@ -1 +1 @@
-{"null": 1.1259691870701642}
\ No newline at end of file
+{"ABATACEPT": 0.4214247001855507, "ADCIRCA": 3.919718180451196, "AFINITOR": 0.8529962153950628, "ANAKINRA": 4.936980995699163, "APIDRA": 3.83754297624723, "ARANESP": 1.4378837257322503, "ARAVA": 2.3168069611216326, "AUBAGIO": 0.9576837082176493, "BENLYSTA": 4.7028537016138685, "BYDUREON": 5.11962223598584, "BYETTA": 1.221525201840749, "CELLCEPT": 1.6185172667790966, "CICLOSPORIN": 0.7842626459540785, "CIMZIA": 1.677365948028871, "COMIRNATY": 0.102184279298097, "COSENTYX": 1.604590795949682, "CYMBALTA": 1.684126973423215, "DARATUMUMAB": 28.256979611010827, "ELIQUIS": 1.3685821407524736, "ENBREL": 3.8777537447625474, "ENTRESTO": 0.5650045745665272, "ENTYVIO": 1.3913738862442608, "EXFORGE": 2.5455275806635056, "EXJADE": 0.8635246021250008, "FORSTEO": 1.5349557427012603, "FORXIGA": 1.8492543992625416, "HIZENTRA": 1.4046521794229432, "HUMALOG": 7.845119372860901, "HUMIRA": 1.9864497691427965, "IBRANCE": 3.3455749149455616, "ILARIS": 94.1912156113165, "INLYTA": 2.178475339739858, "INSULIN": 2.938370815796912, "INVOKANA": 4.982933844170973, "JANUMET": 1.240871544755413, "JARDIANCE": 3.170870456425434, "LANTUS": 5.609575066742089, "LEVEMIR": 7.942854411488962, "LEVOFLOXACIN": 0.6535008836460466, "LYRICA": 1.933429708015441, "MEPOLIZUMAB": 1.5201093347927723, "METHOTREXATE": 2.8023571794986317, "MYCOPHENOLATE": 3.712961503535044, "NEXAVAR": 1.0071277809811436, "OFEV": 1.3351082743770315, "OPSUMIT": 2.3602544682784754, "PEGASYS": 1.2132496216650768, "PEGINTRON": 0.4405405049197202, "RAPAMUNE": 3.5353796968655518, "REVATIO": 2.6587300753078886, "RITUXIMAB": 4.076667251662476, "ROACTEMRA": 4.934769376891997, "SIMPONI": 7.5015166914734435, "SOLIRIS": 1.861956461503567, "SPIKEVAX": 0.194563925076259, "SPRYCEL": 1.4178053541274656, "STELARA": 0.3981497536587384, "SUBOXONE": 0.735303618033228, "SUTENT": 1.9083571759970608, "TOZINAMERAN": 0.437748131680226, "TRACLEER": 1.7417997769778777, "TRELEGY": 2.817277096056066, "VAXZEVRIA": 0.2725542409837236, "VELTASSA": 11.274868997110266, "VFEND": 0.9367772524424468, "VIAGRA": 1.8141562611248676, "VOTRIENT": 1.0617425755582366, "XELJANZ": 9.294544730400832, "XOLAIR": 0.571993778158572, "XTANDI": 1.6552563002889251, "ZOSTAVAX": 0.5557659134260103, "ZYPREXA": 0.4772498538903101, "null": 0.7428385750421941}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7062.json
index c98b558fd03..223ac0de9ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7062.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7062.json
@@ -1 +1 @@
-{"ADENURIC": 109.25715683691053, "ALEMTUZUMAB": 46.69188677116886, "LEMTRADA": 46.67278921735836}
\ No newline at end of file
+{"AFINITOR": 0.7590195776775054, "CHAMPIX": 0.55584389940929, "COMIRNATY": 2.106922663816036, "COSENTYX": 1.752804049900937, "DEXAMETHASONE": 0.9149781445556384, "ENTRESTO": 1.2177684595799654, "GARDASIL": 0.7337900215298485, "HUMALOG": 0.3851163955335609, "JARDIANCE": 0.5637837747255033, "KYMRIAH": 2.921036106234984, "LANTUS": 0.2869869920162577, "MENVEO": 5.199834042457992, "MICARDIS": 1.696129685277466, "MMRVAXPRO": 1.177595707170957, "MODERNA": 1.5002905763494194, "OPSUMIT": 1.8805654459881225, "OPTIMARK": 1.0368625927455544, "PEGASYS": 0.5850734966488847, "REBIF": 19.055221364108395, "SHINGRIX": 0.8340606459551113, "SPIKEVAX": 1.519794363346924, "SUTENT": 0.4533730022574905, "TOZINAMERAN": 0.2986014865080392, "TRACLEER": 1.3683808606161822, "VAXZEVRIA": 0.3480959131196401, "XOLAIR": 1.599905349949241, "ZOSTAVAX": 0.52967261221075, "null": 1.1797479680141392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7063.json
index 55c9735f8d7..c950c15d3a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7063.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7063.json
@@ -1 +1 @@
-{"ABATACEPT": 69.3982950456062, "ADALIMUMAB": 4.9529041049976215}
\ No newline at end of file
+{"RASILEZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7064.json
index 38bc4938fbb..90eef23deff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7064.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7064.json
@@ -1 +1 @@
-{"ABATACEPT": 2.5076774300706712, "AFINITOR": 6.215943004040406, "AIMOVIG": 2.4283902425707447, "ALEMTUZUMAB": 8.389569900968965, "ARAVA": 2.0390654708420626, "ARIPIPRAZOLE": 21.73103580475072, "AVASTIN": 3.812224159576691, "CICLOSPORIN": 1.8597718248175517, "COSENTYX": 1.6448542307849412, "DOCETAXEL": 7.111332685901453, "DULOXETINE": 11.59757426357904, "EMEND": 22.663905494117028, "ENBREL": 1.8870910000901688, "ENTRESTO": 11.609380249174064, "EXJADE": 13.174959563335372, "IBRANCE": 7.306818359373613, "JAKAVI": 15.073945535628592, "KEYTRUDA": 1.3530016809812813, "KYMRIAH": 9.114433446266275, "LEMTRADA": 9.218522099819216, "METHOTREXATE": 3.8916536283309098, "OLANZAPINE": 1.6235577003363215, "PEGASYS": 1.6311945981470504, "RIVAROXABAN": 32.451923574487544, "RUXOLITINIB": 18.3639300344472, "SOLIRIS": 4.156781438887766, "SUTENT": 1.1602371196429888, "VOTRIENT": 2.5339163914717275, "XELJANZ": 3.271684946576185, "ZOSTAVAX": 2.252389260982891}
\ No newline at end of file
+{"ENOXAPARIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7065.json
index 12bc32cffac..765fd825948 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7065.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7065.json
@@ -1 +1 @@
-{"DULOXETINE": 33.32561499749154, "OLANZAPINE": 11.51494444522018, "ZYPREXA": 6.65388253231199, "null": 1.930060706898247}
\ No newline at end of file
+{"EPIVIR": 129.8796683858363, "null": 1.7673645621105456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7066.json
index e64e4ba9f51..6e57225e06f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7066.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7066.json
@@ -1 +1 @@
-{"null": 1.4682857086670595}
\ No newline at end of file
+{"VAXZEVRIA": 4.175009749553353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7067.json
index 4c3ed3fe448..f1ec610f206 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7067.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7067.json
@@ -1 +1 @@
-{"CYMBALTA": 3.082568224084912, "null": 1.8144816835655175}
\ No newline at end of file
+{"null": 3.789616428224515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7068.json
index c92bc387961..0fab88fa23d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7068.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7068.json
@@ -1 +1 @@
-{"ACTOS": 43.27318230488139, "COSENTYX": 7.212499626338817, "FORSTEO": 5.97991362414407, "GARDASIL": 2.867914524971113, "SUTENT": 7.967870008859985, "null": 1.201183889827515}
\ No newline at end of file
+{"COMIRNATY": 2.4639313832451752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7069.json
index 162d541f5d3..c62072cdb31 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7069.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7069.json
@@ -1 +1 @@
-{"MEPOLIZUMAB": 56.16086402178681, "null": 1.017980813242261}
\ No newline at end of file
+{"ARIPIPRAZOLE": 3.998342825051942, "BRINTELLIX": 5.060702051876048, "BUPRENORPHINE": 6.102262964174674, "CHAMPIX": 3.700125593768914, "COMIRNATY": 0.0480712425868481, "CYMBALTA": 1.5079273343552675, "KEPPRA": 3.3411971057354477, "LATUDA": 8.188355011155997, "LYRICA": 2.780618045764589, "OLANZAPINE": 3.668750630263319, "PEGASYS": 0.762287218158213, "VFEND": 6.288063181292692, "ZYPREXA": 3.7534733630240473, "null": 3.6993808947317968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/707.json
index ec01488e254..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/707.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/707.json
@@ -1 +1 @@
-{"LEVETIRACETAM": 20.13979989690805, "NEXAVAR": 5.940329626523916, "null": 3.28877564799773}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7070.json
index 5667f83adc9..4e7378490ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7070.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7070.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 46.7131363565164, "null": 1.6384371366725654}
\ No newline at end of file
+{"BUDESONIDE": 1.8082370153159129, "KALETRA": 25.91751561065719, "LEVOFLOXACIN": 9.005164783356756, "MULTAQ": 11.484943071370012, "OLANZAPINE": 8.324191758799584, "TAGRISSO": 15.736520794768186, "ZYPREXA": 2.101405788258744, "null": 3.989044551731307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7071.json
index c4f555889ab..6d7bad6d07e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7071.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7071.json
@@ -1 +1 @@
-{"ELTROMBOPAG": 3238.828939406906}
\ No newline at end of file
+{"null": 4.152455748155533}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7072.json
index bc9cb93746c..b5fffaf4307 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7072.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7072.json
@@ -1 +1 @@
-{"CYTARABINE": 133.0906916254109}
\ No newline at end of file
+{"ENTYVIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7073.json
index 17f82672e12..4c0646ef5c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7073.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7073.json
@@ -1 +1 @@
-{"ABILIFY": 10.889222495940286, "DACLATASVIR": 164.33060163135738, "EYLEA": 13.90272595391154, "NPLATE": 28.88365778285081, "null": 1.4260203467932235}
\ No newline at end of file
+{"null": 2.530447090273517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7074.json
index 4d656098173..ec20b3b0931 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7074.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7074.json
@@ -1 +1 @@
-{"null": 1.5966242244394038}
\ No newline at end of file
+{"ADALIMUMAB": 47.79062556477066, "ARAVA": 4.246573894063476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7075.json
index 98b3c11d5d1..647cd6b3452 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7075.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7075.json
@@ -1 +1 @@
-{"APREPITANT": 58.52446894248711, "CLOPIDOGREL": 3.09817105176537, "JANUMET": 3.118893004302316, "ROTATEQ": 47.10181395724627, "SAXENDA": 5.1606517877427525, "SUTENT": 1.632877096413977, "TRULICITY": 5.142525928562297, "VOTRIENT": 2.9108483682325774, "XTANDI": 2.222294789879967, "null": 2.177306174766448}
\ No newline at end of file
+{"AIMOVIG": 3.5940766867444007, "ATRIPLA": 2.1689818942965498, "BONVIVA": 27.42327193061157, "COMIRNATY": 0.1637568917017084, "ELIQUIS": 2.2027190867244237, "EVENITY": 17.923837666594252, "FORSTEO": 5.481972941660784, "IBRANCE": 2.644558555850101, "LANTUS": 2.2971071009573896, "PEGASYS": 2.891460078326796, "SUTENT": 6.673930735650829, "TRUVADA": 1.7990838436821324, "null": 0.7304261375188292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7076.json
index f4a0845120f..237e17bc07a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7076.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7076.json
@@ -1 +1 @@
-{"ARANESP": 7.602209643991872, "INCRUSE": 48.49524189841461, "OPSUMIT": 20.047142849401386, "TRELEGY": 30.6047325722367, "VELTASSA": 45.52358652067237, "VOTRIENT": 11.638223904488884, "null": 2.01101300084213}
\ No newline at end of file
+{"ADENURIC": 180.443009541514, "GARDASIL": 8.371365617444159, "null": 2.5355837187549435}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7077.json
index 35481e69b81..39f0ec878bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7077.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7077.json
@@ -1 +1 @@
-{"AUBAGIO": 37.12850789875517, "GARDASIL": 7.419074552804084, "KESIMPTA": 141.534833756436}
\ No newline at end of file
+{"KYMRIAH": 1719.9631390808895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7078.json
index dcb1724a329..3fd1a749926 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7078.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7078.json
@@ -1 +1 @@
-{"KYMRIAH": 95.7618000705373, "RIBAVIRIN": 59.43979644407972, "RITUXIMAB": 133.02310288664484, "SIMEPREVIR": 615.722476591015}
\ No newline at end of file
+{"VAXZEVRIA": 0.9590500843726224, "null": 0.69906305146918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7079.json
index a34d1037e02..7b0ad67eaec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7079.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7079.json
@@ -1 +1 @@
-{"CICLOSPORIN": 79.03874336037859}
\ No newline at end of file
+{"ABACAVIR": 0.0674506010187208, "ABASAGLAR": 0.3970412633633789, "ABATACEPT": 0.1136418085603117, "ABILIFY": 1.1481750239561217, "ACTOS": 1.5919623564016092, "ACTRAPHANE": 6.761450014371626, "ACTRAPID": 2.9668160884171493, "ADALIMUMAB": 0.3074652569964091, "ADCIRCA": 0.5000135784673492, "AERIUS": 1.9040624853572032, "AFINITOR": 0.3249546268753838, "AIMOVIG": 0.9170515016224812, "ALEMTUZUMAB": 0.3011225035623212, "ALIMTA": 0.2729891253709136, "ALL": 1.8582308506138625, "AMBRISENTAN": 0.5411536661793772, "AMIKACIN": 0.3518690849553538, "AMINOSALICYLIC": 0.1486431960991682, "ANAKINRA": 4.948689248931462, "ANORO": 0.5577690060615128, "APIDRA": 3.916156264693912, "APIXABAN": 0.0765939281162267, "APROVEL": 0.9498545775662462, "ARANESP": 0.2601442936415686, "ARAVA": 0.1206123648663408, "ARIPIPRAZOLE": 0.2033482939887877, "ASPARAGINASE": 0.7852667860192942, "ATAZANAVIR": 0.2485149695762746, "ATRIPLA": 0.0320375704515963, "AUBAGIO": 0.5704329581149605, "AVAMYS": 0.2520051900458265, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/708.json
index ca0226a5bf6..8297f395ae1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/708.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/708.json
@@ -1 +1 @@
-{"ABATACEPT": 1.3733428558815195, "ABEMACICLIB": 1.3462203059131626, "ABIRATERONE": 1.4861699159540118, "ADCIRCA": 1.2092933304370934, "AFINITOR": 1.199045045494734, "AFLIBERCEPT": 1.6987422585250749, "AGOMELATINE": 1.0592090299276875, "ALDARA": 1.299321190881538, "ALIMTA": 1.1718206885668672, "ALISKIREN": 1.627314186560984, "ALYMSYS": 5.698428346766091, "AMGEVITA": 2.602966987063198, "APIDRA": 1.0590492326233918, "ATEZOLIZUMAB": 1.109716086965849, "AUBAGIO": 1.0801165200275469, "AXITINIB": 1.0315062391616885, "AYESURBY": 11.257891559444152, "BEDAQUILINE": 1.446700734293741, "BEVACIZUMAB": 1.1038840271134256, "BINOCRIT": 1.4387229420844776, "BRAFTOVI": 1.013700818284624, "BUPIVACAINE": 1.1129434150375404, "CABAZITAXEL": 1.227819202248495, "CABOMETYX": 1.644295615039871, "CABOZANTINIB": 1.732369331305144, "CAPECITABINE": 1.5395725902495256, "CELSENTRI": 1.256570815990575, "CLOPIDOGREL": 1.1023252401166046, "COAPROVEL": 1.0491208229169442, "COBIMETINIB": 1.7490290778223456, "COMIRNATY": 1.750186234478757, "COMPLEMENT": 1.4615559043186888, "COTELLIC": 1.4207339278285906, "COVID19": 1.093060634522767, "DAKLINZA": 1.3100941352000717, "DELAMANID": 1.3030897686160468, "DOCETAXEL": 1.8070258236981724, "DUKORAL": 2.578260237827025, "EDURANT": 1.443774140933962, "ELASOMERAN": 11.8498517621964, "ENALAPRIL": 7.7767120719421134, "ENZALUTAMIDE": 2.531134296221345, "EPCLUSA": 1.3492372413112548, "EPIRUBICIN": 1.152264846499905, "ERBITUX": 1.1191980354755944, "ERIBULIN": 3.5859065693956387, "ESBRIET": 1.77475881168659, "EXELON": 1.0871961663984393, "EXVIERA": 3.371180900629952, "FAMPRIDINE": 1.2543732666852698, "FAMPYRA": 1.2420214771127434, "FASLODEX": 1.1723959241660094, "FIRDAPSE": 2.80691589135434, "FLUCELVAX": 1.1554655894150303, "FORSTEO": 1.6425972639472266, "FOTIVDA": 2.8253715454656567, "FULVESTRANT": 1.2892325357375525, "GARDASIL": 1.3138021269098796, "GAVRETO": 3.0230706475365565, "GILENYA": 1.0100136344632764, "GLIBENCLAMIDE": 1.0233398845258683, "HALAVEN": 2.35350036366075, "HARVONI": 1.2243936129668396, "HERCEPTIN": 1.037222119961866, "HYDROXYCARBAMIDE": 1.0495582198319613, "IBRANCE": 1.392999243980427, "IMNOVID": 1.0690077637661153, "INCIVO": 2.513329247470314, "INLYTA": 1.5675173589052604, "INTELENCE": 1.0675244778120068, "IRINOTECAN": 1.698308539259139, "ISTURISA": 3.367752210476369, "IXIARO": 1.4984737216242248, "JEVTANA": 1.693633573128038, "KARVEZIDE": 1.0250882742890175, "KETEK": 1.1570183010093718, "LENVIMA": 1.045216902419368, "LEUPRORELIN": 1.9728981711889848, "LONSURF": 1.838096373730437, "LUTATHERA": 1.0175949084651543, "LUTETIUM": 1.430549549603587, "LYNPARZA": 1.3401839471397847, "LYSODREN": 2.088182812765148, "MAYZENT": 1.579399752454161, "MENVEO": 1.074279470422406, "MOVYMIA": 2.0222717689019443, "MULTAQ": 1.1362556367634593, "MVASI": 1.8877304454762236, "NERLYNX": 1.840594506481416, "NEXAVAR": 1.489125283763878, "NINLARO": 1.3035966746165526, "NIVESTIM": 1.2831091480892969, "NUBEQA": 1.637934094026445, "OCRELIZUMAB": 1.5653858383422885, "OFEV": 1.0669250287278107, "OLAPARIB": 2.6356532768473744, "OLYSIO": 1.4345295924952657, "ONTRUZANT": 2.8679388065276683, "OPTIMARK": 2.460998829277388, "ORGOVYX": 4.496947953687483, "PACLITAXEL": 1.1264128695922204, "PALBOCICLIB": 1.477915705370741, "PANITUMUMAB": 1.7983427294494914, "PAXLOVID": 1.152648990919762, "PAZOPANIB": 1.0606605831992348, "PEGASYS": 1.832885967962048, "PEGINTERFERON": 1.701512039887449, "PEGINTRON": 1.6028472571309929, "PEMBROLIZUMAB": 1.1862240587066968, "PEMETREXED": 1.298853127463656, "PLUVICTO": 1.3739506811819835, "PRITOR": 1.3530393932952556, "RANEXA": 1.292645439088188, "REBETOL": 2.379686899766692, "REBLOZYL": 3.7133359690424186, "REGORAFENIB": 2.9435838743004075, "REKAMBYS": 1.5403010274303033, "RIBOCICLIB": 1.403737060596663, "RISPERIDONE": 1.5402204816703526, "RUBRACA": 2.229463512257189, "SACITUZUMAB": 3.490035478264735, "SEEBRI": 1.4065499276890032, "SHINGRIX": 1.164792542976195, "SILGARD": 1.143630359504246, "SOLIRIS": 1.0063096979920312, "SORAFENIB": 1.2413394816662142, "SPIKEVAX": 1.1148344578845872, "SPIRONOLACTONE": 3.9685167624373614, "STIVARGA": 2.4641126546249152, "SUNITINIB": 1.8539500895840184, "SUTENT": 2.172801656180704, "TAFINLAR": 2.0298473465254023, "TELAPREVIR": 1.1266140215601832, "TICAGRELOR": 1.4241184635733073, "TOZINAMERAN": 1.3477422324272812, "TRABECTEDIN": 2.1408646200046126, "TRIUMEQ": 1.2291667602589775, "TRODELVY": 2.682341125616676, "TWINRIX": 1.1203774788623522, "TYSABRI": 1.0768886581065586, "VALSARTAN": 1.4397361084798226, "VANDETANIB": 1.8472868853265625, "VAXZEVRIA": 1.9430384118927595, "VECTIBIX": 1.1043347938572587, "VICTRELIS": 1.3556319221617308, "VOTRIENT": 1.4776870420215842, "XALKORI": 1.111833029305324, "XELODA": 1.2376243076790892, "XGEVA": 1.385165150332851, "XOFIGO": 1.581915809891722, "XTANDI": 2.446456551696473, "YONDELIS": 1.7382417355912148, "ZALTRAP": 2.1675024286621385, "ZEJULA": 1.0900393308287673, "ZELBORAF": 1.4336922642008418, "ZYPADHERA": 1.8336940895421776}
\ No newline at end of file
+{"EYLEA": 257.28213530889286, "null": 1.9308669274594548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7080.json
index b54ebe89e72..3fe8836cff5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7080.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7080.json
@@ -1 +1 @@
-{"ATRIPLA": 1.7500027905278774, "FORXIGA": 17.583193771631024, "INVOKANA": 85.79578053450582, "JARDIANCE": 15.970323319193897, "ROACTEMRA": 14.47549316241664, "XALKORI": 63.46430004001686}
\ No newline at end of file
+{"CHAMPIX": 2.421090709512496, "COMIRNATY": 0.647448815807771, "DULOXETINE": 46.89556027241154, "FAMPYRA": 43.21315495784575, "GARDASIL": 2.9039571759100617, "LYRICA": 6.751319415839402, "OPTIMARK": 5.04898358831433, "PLEGRIDY": 17.10173810480187, "SPIKEVAX": 0.5424512146926251, "TOZINAMERAN": 1.7074884388449107, "VAXZEVRIA": 0.994184057756492, "null": 0.7498231760881162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7081.json
index 495696d75a1..ae3a329f272 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7081.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7081.json
@@ -1 +1 @@
-{"ATAZANAVIR": 32.29630567175754, "KEPPRA": 7.226784855403022, "null": 3.570964579397779}
\ No newline at end of file
+{"null": 1.8500677080120336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7082.json
index cc1b0dd445a..9f6251535da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7082.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7082.json
@@ -1 +1 @@
-{"CICLOSPORIN": 38.91404680232824}
\ No newline at end of file
+{"ABATACEPT": 1.7519437154656812, "ABILIFY": 4.88638113707603, "ARAVA": 6.622499167719512, "BUPRENORPHINE": 4.584365703762968, "CHAMPIX": 2.603477485978756, "COMIRNATY": 0.0499038434386477, "FENTANYL": 5.285808410681556, "PLAVIX": 9.380733216575065, "SUBOXONE": 3.0587261210794163, "null": 4.633196155122614}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7083.json
index cadab3aff7f..1d14f47a485 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7083.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7083.json
@@ -1 +1 @@
-{"PONATINIB": 9805.99548923163}
\ No newline at end of file
+{"ABILIFY": 4.211853418058283, "ATRIPLA": 0.1483610926068103, "BIKTARVY": 6.791091788636486, "BRINTELLIX": 8.51980123898211, "CHAMPIX": 2.4345156562230468, "COMIRNATY": 0.2466687751644938, "CYMBALTA": 1.5757657804828389, "DULOXETINE": 4.698920016222589, "FASLODEX": 1.382723520867287, "INFLIXIMAB": 9.51673247549562, "KEPPRA": 1.303090790603725, "LEVETIRACETAM": 1.4630870684121875, "OLANZAPINE": 0.9952514924234384, "SPIKEVAX": 0.1645325432928459, "SUBOXONE": 1.4388298402513675, "TOZINAMERAN": 0.250346738083573, "TRUVADA": 0.4160978208764554, "VAXZEVRIA": 0.1590801407179154, "ZYPREXA": 1.1914762768480307, "null": 5.436495581869472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7084.json
index f1be04a3d3a..e3c0bbfce67 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7084.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7084.json
@@ -1 +1 @@
-{"null": 1.3089659008738577}
\ No newline at end of file
+{"ABACAVIR": 0.1398243889641869, "ABATACEPT": 1.7262470541909625, "ABILIFY": 0.3916930519800915, "ACLIDINIUM": 9.263379861637183, "ADALIMUMAB": 2.210579080891328, "AIMOVIG": 0.0998667108665537, "ALENDRONATE": 19.47849011603824, "AMGEVITA": 15.492275192477829, "AMINOSALICYLIC": 0.8931885240946538, "ANAKINRA": 1.9382731675259592, "ANORO": 17.518069261422145, "APIXABAN": 16.29822028766552, "APREMILAST": 2.978394408819015, "ARAVA": 3.597941986946476, "ARIPIPRAZOLE": 1.5525016538105276, "ATAZANAVIR": 6.755596125308069, "ATRIPLA": 2.398091434901302, "AUBAGIO": 2.953966090328294, "AVAMYS": 11.651558351932549, "AVANDIA": 0.2879455759397902, "AZATHIOPRINE": 1.4105052344376547, "AZOPT": 16.78487835844961, "BELIMUMAB": 9.13361982811423, "BENLYSTA": 0.8438556841642617, "BENRALIZUMAB": 25.913428586370937, "BOSULIF": 0.4360242382921342, "BRAFTOVI": 0.3202390297999956, "BRINTELLIX": 0.3735902607480132, "BUDESONIDE": 9.873777551534156, "BUPRENORPHINE": 0.2050750119626787, "CANAGLIFLOZIN": 9.169782203026308, "CAPSAICIN": 9.354370405041324, "CARBIDOPA": 5.749578091185247, "CAYSTON": 76.23873646718333, "CELECOXIB": 1.5761170578142951, "CELLCEPT": 0.9335848501453092, "CERTOLIZUMAB": 6.8156675913041225, "CHAMPIX": 1.2222367163426913, "CICLOSPORIN": 0.3904081740717304, "CIMZIA": 3.032478427374976, "CLOPIDOGREL": 0.1065888493082546, "COMIRNATY": 0.4818573266226895, "COMTAN": 0.8559178802076516, "COSENTYX": 0.150662033451888, "CYMBALTA": 0.4286754737452005, "DACLIZUMAB": 31.01333890972893, "DAXAS": 16.424389136078307, "DESLORATADINE": 6.004930061983674, "DEXAMETHASONE": 0.7203343188390909, "DULOXETINE": 0.9058018318348257, "DUPIXENT": 5.512050455085209, "ELIQUIS": 0.795929971031142, "ENBREL": 4.698868130929229, "ENTACAPONE": 2.369763036930724, "ENTRESTO": 0.1213747057814721, "ENTYVIO": 0.1732312889730373, "ESBRIET": 0.3440385352274964, "ESOMEPRAZOLE": 1.3475332731815404, "EXJADE": 0.210603632518783, "FAMPRIDINE": 3.0102149107026435, "FASENRA": 0.90546427681745, "FASLODEX": 0.5917941123922533, "FENTANYL": 0.3148380506283587, "FIRDAPSE": 1.227648953733786, "FLUTICASONE": 7.177426701916373, "GARDASIL": 1.3984336577360024, "GLYCOPYRRONIUM": 28.87663885538977, "HIZENTRA": 0.9294296444590718, "HUMIRA": 3.7192402432451823, "HYDROCORTISONE": 0.992416963747903, "IBRANCE": 1.0268256063277306, "IBUPROFEN": 1.0135486149653885, "INCRUSE": 6.226696659294275, "INLYTA": 0.5059203431099114, "INSULIN": 1.4026351027260175, "INVEGA": 1.6795760572979783, "IRBESARTAN": 0.8511714449781924, "IRON": 1.9717582588507927, "JANUMET": 0.1250857322290043, "JANUVIA": 0.508166248393688, "JARDIANCE": 0.2589880294417812, "KEPPRA": 0.4935288964565416, "KEYTRUDA": 0.1459576036844608, "KYPROLIS": 0.7735305805181363, "LANTUS": 0.1531279410749093, "LEFLUNOMIDE": 1.4676455185494963, "LENVIMA": 1.288773705090385, "LEVETIRACETAM": 0.3827412081499403, "LEVOFLOXACIN": 0.3278391934301703, "LIRAGLUTIDE": 37.336905618185625, "LYRICA": 1.775993550050178, "MELATONIN": 0.8198935525415129, "MEPOLIZUMAB": 25.21676261813224, "METHOTREXATE": 2.6107151994741296, "NEULASTA": 0.397427701209143, "NEXAVAR": 0.2126132920245388, "NORVIR": 0.5879069949028166, "NUCALA": 21.008974711478345, "OLANZAPINE": 0.5396617011960735, "OMALIZUMAB": 2.742067620737908, "OPSUMIT": 0.9616834080802328, "OPTIMARK": 1.002142738301738, "PANTOPRAZOLE": 3.926178284698647, "PEGASYS": 0.2244125010014761, "PEGINTRON": 0.0835709009716104, "PLAVIX": 0.16459101185164, "QUTENZA": 1.36805523839113, "REMICADE": 0.6464303834451491, "REVATIO": 0.5744041482764031, "RIBAVIRIN": 0.2408036305451526, "RINVOQ": 0.7472522296676849, "RISPERIDONE": 1.2877963657827267, "RITUXIMAB": 0.2683172670266428, "SHINGRIX": 2.466513469593412, "SIFROL": 1.5582580385797644, "SIMPONI": 0.1471656179814604, "SOMATROPIN": 1.4855215274431026, "SPIKEVAX": 0.5765886472385321, "STALEVO": 1.0051311505345903, "STIVARGA": 0.3986873396043806, "STRIBILD": 2.9151883326726065, "SUBOXONE": 1.2276980275396778, "SUTENT": 0.5811993818338921, "TELMISARTAN": 4.800037831736784, "TOVIAZ": 0.705735948341075, "TOZINAMERAN": 1.735342322838228, "TRELEGY": 1.449221851177233, "TRUVADA": 2.090275867570981, "UMECLIDINIUM": 21.074489103658426, "VARENICLINE": 8.131251014982976, "VAXZEVRIA": 0.2348383693811419, "VIAGRA": 0.7497103350766879, "VIMPAT": 0.3118974676594777, "VIREAD": 2.139403117010488, "XELJANZ": 3.256261376161657, "XOLAIR": 0.2404946560454259, "XTANDI": 0.6574617624940488, "ZOSTAVAX": 0.1808476154513916, "ZYPREXA": 0.2590220584241205, "null": 0.6467043399884509}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7085.json
index 29148477631..4cac6ffd775 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7085.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7085.json
@@ -1 +1 @@
-{"null": 1.4049867443840058}
\ No newline at end of file
+{"COMIRNATY": 0.6301661571455776, "VAXZEVRIA": 0.9327671325705944, "null": 0.8943701082366966}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7086.json
index 3e715bf2608..86fe088df3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7086.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7086.json
@@ -1 +1 @@
-{"ATRIPLA": 1.5055433503392552, "AVANDIA": 3.5803294054449943, "CELECOXIB": 180.81444083313244, "CELLCEPT": 10.28885856057908, "EXFORGE": 8.552600639720499, "ICLUSIG": 64.84892343925344, "MICARDIS": 16.87920973434076, "PLAVIX": 4.385696259218197, "PONATINIB": 587.1133236146788, "RASILEZ": 26.609534044480124, "TASIGNA": 9.94674632921896, "null": 1.2256752284368508}
\ No newline at end of file
+{"ADALIMUMAB": 2.5010504652036154, "CIMZIA": 3.0995583106290168, "COSENTYX": 18.894781516597, "ENTYVIO": 70.22007912047457, "FAMPYRA": 27.00085346917579, "IDACIO": 167.01291200352358, "KEYTRUDA": 2.2155471670500693, "NPLATE": 11.631305082728998, "RINVOQ": 12.474602042207144, "ROACTEMRA": 24.84926502039356, "SIMPONI": 19.728019018088546, "STELARA": 42.71674767512397, "TREMFYA": 53.95921104168303, "XELJANZ": 4.603184317818879, "null": 0.1062340146593342}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7087.json
index 17b421c0b98..2b70a90e6bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7087.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7087.json
@@ -1 +1 @@
-{"PONATINIB": 3435.407529657426}
\ No newline at end of file
+{"null": 1.1188146268798724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7088.json
index cac8fd3bf80..f6832155baa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7088.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7088.json
@@ -1 +1 @@
-{"VAXZEVRIA": 1.6217491540743385}
\ No newline at end of file
+{"ABILIFY": 1.1796312828998912, "ALISKIREN": 3.7021105120111297, "ARIPIPRAZOLE": 5.163547717350982, "ASPARAGINASE": 4.746422462442229, "ATAZANAVIR": 4.713960210523822, "ATOSIBAN": 51.716120868502806, "AZATHIOPRINE": 5.582238689907431, "BUDESONIDE": 0.6965490575380134, "BUPIVACAINE": 10.800702180755744, "BUPRENORPHINE": 20.23023745173055, "CELLCEPT": 1.0748807223007903, "CICLOSPORIN": 9.625669760006462, "CIMZIA": 5.001200151987979, "CINACALCET": 32.968006986081015, "CLOPIDOGREL": 1.5215156131195282, "COMBIVIR": 4.569809732683283, "CYMBALTA": 0.4730335391824004, "CYTARABINE": 2.1407826356628017, "DARBEPOETIN": 17.210922654826184, "DARUNAVIR": 12.485905070491832, "DEXAMETHASONE": 7.402729089576603, "EFAVIRENZ": 6.921882996301598, "EMTRICITABINE": 8.66007261104367, "ENOXAPARIN": 17.467115948530914, "ENTYVIO": 0.9082898876456652, "EPIVIR": 7.499620128094573, "EPOETIN": 13.5985602262372, "FENTANYL": 11.951621813832205, "HUMALOG": 1.590500225645044, "HUMAN": 5.624243711200443, "ILOPROST": 135.5415074795063, "INSULIN": 1.7317265548374894, "IRON": 10.86723075929572, "ISENTRESS": 15.745293569733713, "KALETRA": 1.2001462791005189, "KEPPRA": 7.952697862786559, "LACOSAMIDE": 4.229220586169486, "LAMIVUDINE": 6.447978394621438, "LEVEMIR": 3.628764780791176, "LEVETIRACETAM": 5.970938335265829, "MANNITOL": 14.254371169103957, "MICARDIS": 1.636891399599743, "MIDAZOLAM": 1.9235860185704965, "MYCOPHENOLATE": 2.8153908894174893, "NORVIR": 3.490716487831572, "NOVORAPID": 1.264943740832979, "OSELTAMIVIR": 19.508678938503497, "PANTOPRAZOLE": 2.83521697044234, "RITUXIMAB": 2.100703536647327, "SILDENAFIL": 2.8039679309322456, "SOLIRIS": 2.093504109445224, "SPIKEVAX": 0.0211743553562362, "STELARA": 0.5459418177225867, "SUBOXONE": 20.40385391068085, "TRACTOCILE": 155.90377936877294, "ZYPREXA": 0.5848487171456878, "null": 1.723246778211978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7089.json
index 1c8f54265f4..cdb648540b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7089.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7089.json
@@ -1 +1 @@
-{"ATRIPLA": 7.678372007290936, "TRUVADA": 3.9737051115854354}
\ No newline at end of file
+{"APIXABAN": 26.23219331475025, "JARDIANCE": 11.164882724019574, "null": 1.686282372689046}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/709.json
index f7f38e5d765..49c7b4e8dd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/709.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/709.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1684767097035942, "COSENTYX": 1.6689528050630476, "COVID19": 4.21908167496616, "KEPPRA": 2.401668937120003, "PEGINTRON": 1.2386596748241545, "SHINGRIX": 1.4314215685621794, "TOZINAMERAN": 3.617422208224764, "VAXZEVRIA": 1.0620633137051616, "VIAGRA": 3.332223315647417}
\ No newline at end of file
+{"EYLEA": 92.53621652153348, "null": 5.174002222521232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7090.json
index e09db2e8d0e..73a85bd44c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7090.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7090.json
@@ -1 +1 @@
-{"AFINITOR": 5.492986033279347, "CABOMETYX": 4.805335307821271, "HUMALOG": 1.191064109116439, "INLYTA": 13.607273977950364, "LANTUS": 1.0247682873009378, "NEXAVAR": 3.4458437632729155, "PAZOPANIB": 3.280296527797834, "STELARA": 1.3416694627350614, "SUTENT": 8.196619117836741, "TORISEL": 11.200809613314249, "VOTRIENT": 12.652953125544244, "null": 6.929993338556101}
\ No newline at end of file
+{"null": 0.9114919797986382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7091.json
index dba7dc987a2..7e5e3ce2453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7091.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7091.json
@@ -1 +1 @@
-{"AFINITOR": 4.804312805757988, "CABOMETYX": 39.13278595518814, "INLYTA": 32.32716797200273, "NEXAVAR": 4.367835073890012, "SUTENT": 99.11700097665268, "TORISEL": 55.3993001874512, "VOTRIENT": 55.86992310414446}
\ No newline at end of file
+{"null": 3.776175653564707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7092.json
index 6187ca47675..f4e7c843af9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7092.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7092.json
@@ -1 +1 @@
-{"VOTRIENT": 67.3760101099884}
\ No newline at end of file
+{"ABACAVIR": 6.529795958369237, "AFINITOR": 1.805760659501992, "ARIPIPRAZOLE": 3.670074283232927, "BIKTARVY": 6.782848910948265, "CLOPIDOGREL": 1.9104736823084656, "COMIRNATY": 0.3119570299905024, "CYMBALTA": 1.4105075664233633, "DESCOVY": 27.64040309252692, "ENBREL": 1.4370988725023388, "ENTRESTO": 1.5869769688577298, "JARDIANCE": 2.5513031689946417, "LANTUS": 1.1013842027994392, "METHOTREXATE": 2.965023797082499, "RINVOQ": 32.752083561806664, "ROACTEMRA": 11.423787143884557, "TOZINAMERAN": 0.4879732062158061, "VIAGRA": 2.413573988820143, "XELJANZ": 2.6105099617682543, "ZOSTAVAX": 1.112017960390602, "ZYPREXA": 5.355905437674048, "null": 1.2931053149511655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7093.json
index 2c272ad6eed..50150b6ab1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7093.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7093.json
@@ -1 +1 @@
-{"null": 2.041280120024456}
\ No newline at end of file
+{"COMBIVIR": 55.48362368470901, "KEPPRA": 18.53662332616571, "LAMIVUDINE": 70.34112268644077, "null": 3.092442376318313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7094.json
index 6155c3a27b1..b6d2d92a465 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7094.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7094.json
@@ -1 +1 @@
-{"null": 1.9014649402371044}
\ No newline at end of file
+{"BONVIVA": 901.5967187241832, "null": 0.5861542665449329}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7095.json
index 6ce64265cbf..4a7216820e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7095.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7095.json
@@ -1 +1 @@
-{"null": 1.7937720800506547}
\ No newline at end of file
+{"APIXABAN": 2.5630441215924837, "BEVACIZUMAB": 2.844331067746369, "BRILIQUE": 9.758102592820276, "CLOPIDOGREL": 37.247769538225846, "COSENTYX": 5.7897014743345485, "DEFITELIO": 31.192443568856344, "ELIQUIS": 16.638067734364014, "ENOXAPARIN": 13.996668065213663, "IBUPROFEN": 2.552378735170446, "LIXIANA": 17.50273654570032, "NEXAVAR": 4.407844073319892, "OFEV": 2.404607702312918, "PLAVIX": 33.276564058053346, "PRADAXA": 24.7932824941684, "REVATIO": 4.3606054968789225, "SPRYCEL": 3.1101176952098406, "STIVARGA": 2.869987148046988, "TICAGRELOR": 62.99539964068568, "XARELTO": 65.06573702400466, "null": 0.8390135234082853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7096.json
index 87242709f2b..a7e26017afc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7096.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7096.json
@@ -1 +1 @@
-{"SUTENT": 61.7367832319189, "VOTRIENT": 28.274708536600084}
\ No newline at end of file
+{"ABATACEPT": 1.3714580807663057, "ADALIMUMAB": 2.3123451828357, "AERIUS": 9.57511657116676, "AIMOVIG": 0.4538870925935797, "AMINOSALICYLIC": 3.048400734091228, "APIDRA": 0.8975422206691874, "APIXABAN": 0.6158503754486566, "APREMILAST": 16.03664259157772, "ARAVA": 2.57124616805886, "ATRIPLA": 8.790829364997713, "AUBAGIO": 1.8706948332333044, "AVANDIA": 0.8104623171773373, "BONVIVA": 3.8275476501795023, "BOTULINUM": 4.2809660198862645, "BYETTA": 0.9702420832824746, "CIMZIA": 0.7831034888276128, "COMIRNATY": 0.0172869508270594, "COSENTYX": 2.051920025981963, "CYMBALTA": 0.7672904161504933, "DOCETAXEL": 2.212977942913557, "ELIQUIS": 2.213824897610944, "ENBREL": 0.3941654252169179, "EVENITY": 3.490797371104312, "EVISTA": 4.116776823281052, "EXFORGE": 2.221003507566298, "EXJADE": 1.341805896315029, "FAMPYRA": 4.54896006127693, "FORSTEO": 2.7359903862311987, "GALVUS": 3.388460787807487, "HUMALOG": 4.079293924346634, "HUMIRA": 2.119485927613176, "IBRANCE": 2.648955341056605, "INLYTA": 0.9665411220686128, "INSULIN": 0.9980189575441808, "IRON": 8.687233850288493, "JARDIANCE": 0.6937273518076487, "KALETRA": 1.0403089271949175, "KEPPRA": 0.6251656477381755, "LANTUS": 3.170608769524089, "LEVEMIR": 3.1441791997636392, "LEVOFLOXACIN": 0.8208563729770549, "LYRICA": 2.793669851973885, "OPSUMIT": 1.1711879474997764, "PEGASYS": 0.1812603221357761, "PEGINTRON": 0.3395095754417199, "RAPAMUNE": 3.085301404062286, "REVATIO": 5.193695716837231, "SIMPONI": 3.496884685082009, "SOMATROPIN": 9.307119250187409, "SPIKEVAX": 0.0207841804381217, "SPINRAZA": 6.242113081147199, "STELARA": 0.6476621662835401, "STRIBILD": 6.724854728671521, "SUBOXONE": 3.7590065006657714, "SUTENT": 0.5451075477995418, "TAMIFLU": 2.0152148927423266, "TOZINAMERAN": 0.1208489038624792, "TRACLEER": 1.6244003605649906, "TRELEGY": 3.2840106038882344, "TRUVADA": 6.635368640602052, "VAXZEVRIA": 0.0178072180435685, "VELTASSA": 5.364909615279473, "VIAGRA": 5.199416524804963, "VIREAD": 3.7160225128186983, "XELJANZ": 5.521994731044636, "XOLAIR": 0.7184752945523103, "XTANDI": 1.653507597905151, "null": 0.7955277484452391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7097.json
index e6cc0df5fec..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7097.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7097.json
@@ -1 +1 @@
-{"AFINITOR": 9.650104782768585, "AXITINIB": 7.949600331180702, "AZATHIOPRINE": 1.573584952520409, "CABOMETYX": 63.30461049153871, "CELLCEPT": 1.1290463219121076, "CICLOSPORIN": 1.4397768631590016, "EVEROLIMUS": 22.852939290475664, "INLYTA": 24.345961508837025, "NEXAVAR": 27.15587457743393, "PAZOPANIB": 29.374748934370736, "SORAFENIB": 15.910019249109528, "SUTENT": 136.53176194939937, "TORISEL": 84.2343429833472, "VOTRIENT": 17.74960585889205}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7098.json
index e333c7bbbf0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7098.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7098.json
@@ -1 +1 @@
-{"CABOMETYX": 143.73835234563762}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7099.json
index c3703fab9ae..196e0d5e59b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7099.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7099.json
@@ -1 +1 @@
-{"SUTENT": 33.89965694990128, "VOTRIENT": 72.01231778799871}
\ No newline at end of file
+{"ARAVA": 1.352676876885648, "COMIRNATY": 0.2455754473795142, "COSENTYX": 14.643002869057655, "JANUVIA": 13.978001519025815, "MEPOLIZUMAB": 12.101453220457854, "METHOTREXATE": 18.25491608987079, "null": 0.9732959666398908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/71.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/71.json
index f10c6aa389c..963326144e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/71.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/71.json
@@ -1 +1 @@
-{"ABILIFY": 3.7244892433680135, "AUBAGIO": 1.232704687941684, "BUPRENORPHINE": 2.315398073472308, "BYETTA": 1.3869109939813131, "CHAMPIX": 1.5647839163034387, "CIMZIA": 1.095651468586036, "COSENTYX": 1.5606660827331855, "ELIQUIS": 3.530857527375631, "EVENITY": 5.144035107094759, "FAMPYRA": 10.083547691487958, "FORSTEO": 2.157436460917814, "HUMALOG": 5.134296090486663, "IBRANCE": 2.571229126322253, "JANUMET": 4.077428397369374, "JANUVIA": 1.1610176613043044, "KEPPRA": 2.2705055821711326, "LANTUS": 2.685401816807518, "LEVEMIR": 2.2698265090541785, "LYRICA": 1.3275927971605592, "MEPOLIZUMAB": 3.301851753700737, "NUCALA": 1.4857677570122343, "OMALIZUMAB": 3.056239258440144, "PEMBROLIZUMAB": 2.472498645656977, "SIMPONI": 3.2820869986107435, "STELARA": 2.0397386364029297, "SUBOXONE": 6.762251077999265, "TOVIAZ": 4.687288606191155, "TRELEGY": 4.670951309476404, "VIAGRA": 9.273741952947256, "XELJANZ": 6.442149234436229, "XOLAIR": 1.110160583827766, "XTANDI": 1.166506265276534, "null": 1.6234161379836909}
\ No newline at end of file
+{"ABACAVIR": 0.8586127114278111, "ABILIFY": 1.4934196933728088, "ACTRAPID": 7.237452877445067, "ALISKIREN": 7.836776543866765, "ARAVA": 0.495254589180707, "ATAZANAVIR": 4.15209150401844, "AUBAGIO": 1.5653129149291454, "BARACLUDE": 27.71601358098749, "BIKTARVY": 4.250644590181727, "BUPRENORPHINE": 1.521749831356091, "CELLCEPT": 1.2308319272386612, "CIMZIA": 1.1868582486601655, "COMBIVIR": 20.807068118388536, "COMIRNATY": 0.0642201837553672, "DARUNAVIR": 8.596154161342085, "EFAVIRENZ": 5.908968048573806, "ELLAONE": 131.69229441514122, "ENOXAPARIN": 2.8455308581124723, "EPIVIR": 5.778234555351153, "FENTANYL": 4.205399165786487, "GARDASIL": 11.804580931956572, "GENVOYA": 15.898322827889846, "INTRONA": 12.54486533736513, "ISENTRESS": 9.153724316416694, "KAFTRIO": 5.157557927264396, "KALETRA": 12.278900884533607, "KEPPRA": 6.1130793150500295, "LAMIVUDINE": 7.052488303638123, "LANTUS": 0.3755230692776983, "LEVEMIR": 1.790274048326436, "LEVETIRACETAM": 3.8912446113691455, "MIDAZOLAM": 2.330625203062013, "OLANZAPINE": 0.6092715492638429, "OPSUMIT": 0.8738910832409016, "PEGASYS": 1.8055764894950688, "PEGINTRON": 7.867377124620278, "REBETOL": 7.991108066830665, "RINVOQ": 2.406804424088067, "STELARA": 0.4856852955561165, "STOCRIN": 55.492594492243846, "SUBOXONE": 10.19387658775518, "TRACLEER": 6.086982017000009, "TRUVADA": 0.2406469779786898, "VICTOZA": 2.269839524617488, "VIMPAT": 4.636131950338319, "ZYPREXA": 0.5892382872473712, "null": 1.668774478483312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/710.json
index 61f3aa553f4..c99ba9e5635 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/710.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/710.json
@@ -1 +1 @@
-{"null": 1.280142941968354}
\ No newline at end of file
+{"BEOVU": 1576.6926865036194, "BROLUCIZUMAB": 402.1795221334658, "EYLEA": 113.56171367092536, "LEVOFLOXACIN": 14.985443964804045, "null": 0.9677343982190334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7100.json
index fe448f4c04c..6dede4261ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7100.json
@@ -1 +1 @@
-{"ATAZANAVIR": 6.483783072034165, "BIKTARVY": 8.771942670261758, "COMBIVIR": 8.644779808125227, "CRIXIVAN": 98.84856729281594, "EXJADE": 2.2673169375475566, "FORSTEO": 5.665711244064321, "FORXIGA": 4.7761402664022725, "ISENTRESS": 9.77102354747226, "JARDIANCE": 1.761587404641435, "KIVEXA": 40.01624325571736, "NORVIR": 126.2362430253976, "PEGASYS": 1.6563825709173907, "REYATAZ": 435.5994258054364, "SAXENDA": 5.149954318320227, "SIMPONI": 1.86530854719824, "XOLAIR": 1.9047613722477224}
\ No newline at end of file
+{"DEXAMETHASONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7101.json
index 3216794c91b..c1af6991d84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7101.json
@@ -1 +1 @@
-{"NOVOSEVEN": 426.38523158099525, "null": 2.0863895033321707}
\ No newline at end of file
+{"ABATACEPT": 17.766568993545725, "ACETAMINOPHEN": 31.46455341163997, "ACLIDINIUM": 5.4037397425142055, "ADALIMUMAB": 2.670590427251921, "AFINITOR": 0.4847714401382402, "ALEMTUZUMAB": 0.7795896046709515, "AMINOSALICYLIC": 1.0123912537974975, "ANORO": 2.043247619570736, "APIXABAN": 0.1830778963530022, "APREMILAST": 1.0914761986933188, "APREPITANT": 3.8057202539450303, "ARANESP": 1.4600359036935855, "ARAVA": 8.20563566790455, "ARIPIPRAZOLE": 1.2296596145553216, "AUBAGIO": 0.2778755174000197, "AVAMYS": 1.634733424412802, "BELIMUMAB": 5.316073800425885, "BENLYSTA": 1.5317653126284927, "BORTEZOMIB": 2.107260136192868, "BOTULINUM": 1.4237830266960576, "BUDESONIDE": 4.080977361025123, "BYDUREON": 0.2424713416372159, "CABOMETYX": 0.3891646173748204, "CELECOXIB": 1.3674450981670234, "CELLCEPT": 0.2585088588210353, "CHAMPIX": 0.8308569337131491, "CHLORHEXIDINE": 52.15758702987159, "CICLOSPORIN": 0.6842900949682741, "CIMZIA": 20.259104689155127, "CLOPIDOGREL": 0.5154857302376709, "COMIRNATY": 0.1363361670162164, "COSENTYX": 3.628507330451353, "CYMBALTA": 0.1016216266959187, "DAPTOMYCIN": 17.48120855997858, "DARATUMUMAB": 7.665860095136718, "DARZALEX": 0.8512501594431491, "DEXAMETHASONE": 1.1567019370495, "DOCETAXEL": 0.5151608118072357, "ELIQUIS": 0.3073692554158636, "ENBREL": 3.809324193818004, "ENTRESTO": 0.7162468667843312, "ENTYVIO": 2.836568719064037, "ENVARSUS": 19.765855286211934, "ERELZI": 8.493566585372173, "ESBRIET": 2.230191158419984, "ETANERCEPT": 7.910956692669164, "EXJADE": 0.2240194181820028, "FAMPYRA": 1.211457120065768, "FASENRA": 3.32124828335017, "FILGRASTIM": 1.068024992664265, "FLUTICASONE": 3.511019991099193, "FORSTEO": 0.444718993340552, "GARDASIL": 0.123133268255889, "GLYCOPYRRONIUM": 2.5610268125243865, "HIZENTRA": 2.682925255139002, "HUMALOG": 0.1058615913630298, "HUMAN": 0.8431099910115964, "HUMIRA": 0.9995384533405354, "HYDROCORTISONE": 1.0648125662066452, "HYQVIA": 3.636736275162868, "IBRANCE": 0.5754342240244736, "IBUPROFEN": 0.4106758640852198, "INCRUSE": 1.1883505516074733, "INFLECTRA": 7.38610264072766, "INFLIXIMAB": 2.406097792199618, "INLYTA": 0.6318179613551563, "INSULIN": 3.3542535375129336, "IRON": 2.410506637635884, "JAKAVI": 0.5064005794455774, "JANUVIA": 0.6049006526151305, "JARDIANCE": 0.310823327909258, "KAFTRIO": 17.360559333352267, "KALYDECO": 15.181994393094431, "KEPPRA": 0.1420899896999643, "KEYTRUDA": 0.2044858031881017, "LANTUS": 0.3797854561951996, "LEFLUNOMIDE": 2.121232657992403, "LEMTRADA": 0.9917675219223856, "LEVOFLOXACIN": 0.2307947536301737, "MEKINIST": 0.6644927662129573, "MEPOLIZUMAB": 8.443928817877309, "METHOTREXATE": 2.9762858626803506, "NAGLAZYME": 0.9291276624340732, "NEULASTA": 0.6193897181279093, "NEXAVAR": 0.2217427847178916, "NOT": 1.2235623913488731, "NUCALA": 3.503039400577626, "OBINUTUZUMAB": 3.6044861194639073, "OLANZAPINE": 0.2885742933401961, "OMALIZUMAB": 6.1648206765535205, "OPSUMIT": 0.4129695839993596, "ORKAMBI": 2.3053675980509354, "PEGASYS": 0.3673909088435257, "PEMBROLIZUMAB": 0.5751534347760888, "PIRFENIDONE": 7.363690924686139, "PLEGRIDY": 1.0306860817949586, "POMALIDOMIDE": 4.200290165033403, "PRIVIGEN": 0.6988409674938897, "RANIBIZUMAB": 119.9638786744081, "RELVAR": 2.415331173572774, "REMICADE": 1.106642193989024, "REMSIMA": 38.60930812577993, "RINVOQ": 0.3278709188069608, "RITUXIMAB": 1.9021525677752096, "ROACTEMRA": 2.680381432869446, "SAXENDA": 0.3543374965435062, "SHINGRIX": 0.1459934538228497, "SIMPONI": 31.367890146220507, "SOLIRIS": 0.634197030672021, "SPIKEVAX": 0.1157097413953061, "SPINRAZA": 1.66235556822652, "SPRYCEL": 0.3678126974551695, "STELARA": 3.091282846143608, "SUTENT": 0.532730874919118, "SYNAGIS": 6.14019488803452, "TASIGNA": 0.4542575772801295, "TOBI": 10.94610738108935, "TORISEL": 1.3016911605490442, "TOZINAMERAN": 0.7640561580152104, "TRACLEER": 0.2395194866478614, "TRELEGY": 5.432254136742325, "TREMFYA": 0.8616946390529545, "ULTIBRO": 13.073612994098845, "UMECLIDINIUM": 6.281172982238171, "VAXZEVRIA": 0.221826867951674, "VOTRIENT": 0.5089492973292327, "XELJANZ": 7.207513310810467, "XOLAIR": 2.619215877332144, "XTANDI": 0.15258578970486, "ZOSTAVAX": 0.177166278927333, "null": 0.2964613225757487}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7102.json
index 63690530062..5c5081812ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7102.json
@@ -1 +1 @@
-{"ACLIDINIUM": 9.99700219557947, "AFINITOR": 1.5174535760842325, "ARANESP": 1.035581032281775, "ATRIPLA": 8.599351473558642, "BEVACIZUMAB": 1.8967485478539572, "BYDUREON": 2.2557089531428205, "BYETTA": 11.820188590118477, "CICLOSPORIN": 1.0501874486457536, "ETANERCEPT": 16.668164453284717, "EXFORGE": 1.942287564594988, "EXJADE": 2.340320063791559, "FASLODEX": 1.6583728987780273, "FORSTEO": 1.4205058993746544, "FORXIGA": 2.1802354118979985, "JANUMET": 18.660443414514063, "JANUVIA": 16.592072601003256, "OPTIMARK": 1.6911135466871656, "PEMBROLIZUMAB": 3.613544137050373, "SIMPONI": 1.2266853333161294, "STRIBILD": 2.4887361267350983, "TRUVADA": 3.7235298802991386, "VIREAD": 3.4733137808356984, "XALKORI": 16.689673689554763, "ZOSTAVAX": 3.605832204091211, "ZYPREXA": 1.127187254282523, "null": 1.0437993394888387}
\ No newline at end of file
+{"null": 0.6007936926312785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7103.json
index dfcd7fc8f22..0ce0c00f379 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7103.json
@@ -1 +1 @@
-{"ABILIFY": 1.5688270804953648, "ACTOS": 1.888710724707706, "ADCIRCA": 2.2618408933462346, "AFINITOR": 1.4737269825163135, "ALIMTA": 2.302294347555595, "APIDRA": 2.498579569981992, "APIXABAN": 19.46527713575368, "ARANESP": 2.015231458544135, "ATRIPLA": 1.9293900758257203, "AUBAGIO": 1.01318028256106, "AVANDAMET": 1.0601556622672406, "AVANDIA": 1.8191237430590048, "BELIMUMAB": 16.598411222300783, "BENLYSTA": 2.4359538115030466, "BIKTARVY": 1.2606161622180745, "BOSULIF": 3.429015322118524, "BRAFTOVI": 2.425954542325994, "BYETTA": 2.2197478446072907, "CABOMETYX": 1.3339752114372572, "CELLCEPT": 1.5195364152251258, "CICLOSPORIN": 2.212985809177336, "COMBIVIR": 1.5137261766909105, "CRIXIVAN": 2.802216345318355, "CUBICIN": 1.0329759130382112, "DESCOVY": 4.828920875186944, "DOLUTEGRAVIR": 3.6878288503511856, "DULAGLUTIDE": 2.627784296921303, "ELIQUIS": 3.790555560394984, "EMPAGLIFLOZIN": 5.326138401352498, "EMTRICITABINE": 2.907114031179442, "ENBREL": 2.129471149492681, "ENTRESTO": 3.146799927914082, "EPIVIR": 1.6108020564486072, "ESOMEPRAZOLE": 1.177923360305955, "EXFORGE": 3.3375732780894536, "EXJADE": 8.50468473112307, "FORSTEO": 1.014470050521681, "FORXIGA": 2.231413556772083, "GALAFOLD": 2.878488758846533, "GALVUS": 3.578620797460533, "GANCICLOVIR": 2.987806319402204, "HARVONI": 1.0094764486366443, "HEPSERA": 9.788483822973008, "HIZENTRA": 1.6014647168008525, "HUMALOG": 5.050404347458047, "HYDROCORTISONE": 1.033051665980747, "IBRANCE": 1.842148426326588, "ICLUSIG": 1.0369443521153292, "INLYTA": 2.2510065042937533, "INSULIN": 2.031210828396933, "IRON": 1.894416857845284, "ISENTRESS": 2.0957692578020204, "JANUMET": 2.9591753498991547, "JANUVIA": 2.030781637757403, "JARDIANCE": 1.2522503297052867, "JEVTANA": 1.0192871369276202, "KALETRA": 2.422920600686157, "KEYTRUDA": 1.89907695701636, "KYPROLIS": 3.0720149174555167, "LANTUS": 5.358813356077079, "LENVIMA": 1.7536517456599878, "LEVEMIR": 2.3261728046523658, "LYNPARZA": 1.4190256127151115, "LYRICA": 1.8506224452959303, "METHOTREXATE": 2.22583144362492, "MICARDIS": 1.8446327755311296, "NINLARO": 2.223320683598701, "NORVIR": 1.2278983515317352, "ONGLYZA": 2.805551393513519, "OPDIVO": 2.858053983501152, "OPSUMIT": 1.740353745406959, "OZEMPIC": 4.571270239332722, "PEGINTRON": 1.7889983179901132, "POSACONAZOLE": 3.7159085975667394, "RAPAMUNE": 6.511692220731865, "RASILEZ": 2.932808354900674, "REVATIO": 4.208431615015384, "REVLIMID": 2.5355254187771683, "RUBRACA": 1.7632485077500943, "SIMPONI": 1.2618558489636265, "SOLIRIS": 1.8211428988993703, "SPRYCEL": 1.2748521384273674, "STRIBILD": 1.8618647976158091, "SUTENT": 2.265627252494817, "TACROLIMUS": 1.701037748189379, "TAMIFLU": 1.0947200848557703, "TASIGNA": 1.1052527126349672, "TOUJEO": 3.1431770715059093, "TOVIAZ": 1.5613597180914882, "TRACLEER": 1.4273021167501727, "TRULICITY": 2.34001483427858, "TRUVADA": 1.8842707899610864, "VELTASSA": 9.087973656962811, "VFEND": 2.286695167797914, "VIAGRA": 1.9653299820098251, "VICTOZA": 1.602585782314616, "VIREAD": 2.888561970177501, "XALKORI": 1.50589434626648, "XELJANZ": 2.0332118673671187, "XTANDI": 1.1483436877184676, "XYREM": 1.8691581466785976, "null": 1.0838249145215864}
\ No newline at end of file
+{"BUSULFAN": 48.57196766126733, "CASPOFUNGIN": 314.3160854528656, "null": 0.3347531365281468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7104.json
index 4571372398c..c92e7f0f257 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7104.json
@@ -1 +1 @@
-{"ATAZANAVIR": 67.53768970241616, "KALETRA": 46.50101151080655, "null": 2.9833298514770688}
\ No newline at end of file
+{"COSENTYX": 21.985502413974004, "null": 0.3901139971246022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7105.json
index 1adb98a106e..ebf8735b431 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7105.json
@@ -1 +1 @@
-{"null": 1.027644819758759}
\ No newline at end of file
+{"null": 0.9716065362989734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7106.json
index 91f1bc3a1f1..b20cc4398b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7106.json
@@ -1 +1 @@
-{"ACTOS": 1.870701416648088, "ADEFOVIR": 2.0294314169901075, "ADENURIC": 2.572935342165042, "ADVAGRAF": 1.3047215475756035, "AFINITOR": 1.4986789574248944, "ALIMTA": 3.8701610265979496, "AMIKACIN": 1.214612711595442, "ANAKINRA": 2.5998176343247703, "ANTIBIOTICS": 1.9069399081018423, "APROVEL": 4.175709939851741, "ATRIPLA": 20.318526495366758, "AVANDAMET": 1.1457966121186391, "AVANDIA": 2.0501693966716874, "BARACLUDE": 2.0194880397442945, "BASILIXIMAB": 1.0638182497952964, "BEXTRA": 1.8532890842491685, "BIKTARVY": 1.4070556200167088, "BORTEZOMIB": 1.8936728295164047, "BOSULIF": 1.421214841601545, "BUMETANIDE": 1.250639759967067, "BUSILVEX": 1.6212892479057197, "BUSULFAN": 1.109994303290939, "BYETTA": 2.104690136528696, "CANAGLIFLOZIN": 1.355528941567142, "CANCIDAS": 1.4771058649382802, "CARFILZOMIB": 2.457708653547597, "CASPOFUNGIN": 2.358619087469169, "CELECOXIB": 2.5725264056595822, "CELLCEPT": 1.7655887234369243, "CICLOSPORIN": 1.757401889333233, "CIDOFOVIR": 2.290129625039424, "COAPROVEL": 3.9826223539431886, "COTELLIC": 2.4691754387645224, "CRIXIVAN": 2.749757878233725, "CUBICIN": 2.4700042221524687, "DACLATASVIR": 1.6033385186847402, "DEFITELIO": 3.230789069083278, "DESCOVY": 1.9081172111716709, "DULAGLUTIDE": 1.4691644249641111, "EMTRICITABINE": 1.1084620146634447, "EMTRIVA": 3.451983575293134, "ENTRESTO": 4.468865087174, "EUCREAS": 1.2832001814757183, "EXFORGE": 1.5237783774723137, "EXJADE": 2.904039509973888, "EXVIERA": 2.0668441056368168, "FEBUXOSTAT": 2.870292419130249, "FORXIGA": 1.2611025171346175, "FUZEON": 4.777526412678703, "GALVUS": 1.4874494434636, "GANCICLOVIR": 2.20535036530226, "GENVOYA": 1.4438476428566394, "HARVONI": 1.2147762469202668, "HEPSERA": 2.164966829025518, "HUMALOG": 1.3428398579122744, "IBUPROFEN": 1.4998589326134817, "IMNOVID": 1.3314608441944231, "INCIVO": 1.858611853382711, "INTELENCE": 2.137193343868846, "INTERFERON": 1.0271730600611495, "INVIRASE": 2.257577482001422, "INVOKANA": 3.2654391480733995, "IRBESARTAN": 1.5814121698950552, "ISENTRESS": 1.6779736781997658, "ISOPHANE": 2.082694021944888, "JANUMET": 1.6750368017769413, "JANUVIA": 1.656502491723722, "JARDIANCE": 1.218556749430482, "KALETRA": 4.21656798986675, "KARVEA": 2.037714341154249, "KIVEXA": 1.3316369275298872, "KYPROLIS": 2.8325731897393047, "LANTUS": 1.3303892534107975, "MEKINIST": 1.166699743070858, "MELPHALAN": 1.1021830004184423, "MICARDIS": 1.45628389147654, "MIXTARD": 1.5318584711515684, "MULTAQ": 1.834468668589545, "MYCAMINE": 1.5020100142050188, "NORVIR": 2.4082603796219657, "NOXAFIL": 1.7366451964916396, "NPLATE": 1.1324597995994676, "OLAPARIB": 1.148506574151002, "OLYSIO": 1.6145911335362464, "ONGLYZA": 1.5525212005781708, "PEMETREXED": 1.7762029910027652, "POMALIDOMIDE": 1.7190947014560898, "PRADAXA": 2.779893202048421, "PRAXBIND": 2.3720935026661145, "RANOLAZINE": 1.4753414131853746, "RAPAMUNE": 2.783607583898177, "RASBURICASE": 2.247069171503802, "RASILEZ": 3.170024397725097, "REMDESIVIR": 2.3525759179727714, "RENVELA": 4.79618968911098, "REVATIO": 2.062744533935849, "REVLIMID": 2.029300591031848, "REYATAZ": 2.8103017615482604, "ROSIGLITAZONE": 1.5204318979357918, "SAMSCA": 2.63273681633115, "SIMEPREVIR": 1.3040195699717907, "SOLIRIS": 1.5295040342177997, "STRIBILD": 16.00421654754964, "SUNITINIB": 1.1476851184801484, "SUSTIVA": 1.3619115170850462, "SUTENT": 1.1833752516041476, "TELMISARTAN": 1.632986808602377, "TENOFOVIR": 3.5900369824311653, "THALIDOMIDE": 1.3150312715237742, "TIVICAY": 2.317494151286797, "TOBRAMYCIN": 1.5373140395682745, "TORISEL": 3.3586739360783544, "TRACLEER": 1.3227367625049835, "TRISENOX": 2.459959758845987, "TRUVADA": 22.710740840214225, "VALSARTAN": 1.186431295844248, "VEKLURY": 1.737331997915615, "VELCADE": 1.4929474757894552, "VELMETIA": 3.589475444829251, "VELTASSA": 2.843566311214428, "VFEND": 1.6025413961833297, "VICTOZA": 1.7390934344831055, "VIREAD": 15.05628439390915, "VISTIDE": 4.997215000637539, "XARELTO": 1.0212836609957214, "XENICAL": 2.9713598274169324, "YONDELIS": 3.931701952138176, "ZELBORAF": 1.6781807825519326}
\ No newline at end of file
+{"ZOSTAVAX": 16.172430960857923, "null": 1.022072236146629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7107.json
index a4fdcb5e490..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7107.json
@@ -1 +1 @@
-{"null": 3.4946834248401237}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7108.json
index 3141d06c2b1..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7108.json
@@ -1 +1 @@
-{"ABACAVIR": 2.818740823808979, "AFINITOR": 2.125804950082524, "AMLODIPINE": 236.61149787421976, "CAFFEINE": 431.05760751341165, "CICLOSPORIN": 1.1252452790368936, "CLOPIDOGREL": 1.9841896641560213, "ELIQUIS": 2.2595473778868884, "ENTRESTO": 5.806817070336124, "EXJADE": 10.870881320319434, "FORXIGA": 3.1404216714216275, "HEPSERA": 23.30656627631284, "IBRANCE": 1.263396791051653, "JARDIANCE": 2.1647041880751776, "KEYTRUDA": 1.1960575404038358, "LEVOFLOXACIN": 32.89275412285276, "LIXIANA": 9.606183613855508, "OPSUMIT": 1.718025957869791, "ROACTEMRA": 2.591779240194443, "RUBRACA": 28.269337352129163, "STELARA": 1.3247525496947243, "STRIBILD": 1.4087122384686324, "SUTENT": 1.4387720701707152, "TRUVADA": 2.0454385329692077, "VOTRIENT": 1.868823335578717, "XELJANZ": 1.3888001569772876}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7109.json
index afcbb3addca..cd6b49cdae7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7109.json
@@ -1 +1 @@
-{"LEVETIRACETAM": 59.24527710191733, "null": 1.2390277973930015}
\ No newline at end of file
+{"null": 0.7127343957588432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/711.json
index 6c051c9c85e..1301af95fee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/711.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/711.json
@@ -1 +1 @@
-{"ABACAVIR": 11.18705619156061, "ABATACEPT": 2.47057454260862, "ABILIFY": 1.6112447130611751, "ACLIDINIUM": 16.034088047566755, "ADALIMUMAB": 1.8811848299651663, "AERIUS": 1.0491012569517846, "ALENDRONATE": 9.637413100481346, "ANORO": 9.537442769045224, "ANTIBIOTICS": 1.20258615354141, "ANTIHYPERTENSIVES": 5.792623423146339, "APIXABAN": 10.779404910037432, "APREPITANT": 1.4584316995445814, "AVAMYS": 14.703660184489836, "AZATHIOPRINE": 1.3233122477533616, "AZOPT": 9.995585176547452, "BENRALIZUMAB": 32.93761781885751, "BUDESONIDE": 15.281180047135278, "CANAGLIFLOZIN": 21.40505444473037, "CAYSTON": 37.69826354541946, "CORTICOSTEROIDS": 1.6723234886884373, "DARUNAVIR": 1.0402890603813078, "DAXAS": 25.290203684662824, "DESLORATADINE": 5.409335148203829, "DUAKLIR": 11.010746998560393, "DUORESP": 14.38718825501912, "DUPILUMAB": 5.484930631895915, "DUPIXENT": 8.733155971240059, "ESOMEPRAZOLE": 1.2337769675325911, "FASENRA": 27.19732619552656, "FLUTICASONE": 19.73005994287271, "FORMOTEROL": 42.41947574465548, "GLYCOPYRRONIUM": 25.77078757650816, "HIZENTRA": 1.6872059308388931, "HUMIRA": 1.033063718196847, "HYDROCORTISONE": 1.628227459496827, "INCRUSE": 7.076449886107372, "INSULIN": 1.324840675818001, "INVOKANA": 1.250905169572086, "IRON": 2.347636066606361, "LIRAGLUTIDE": 18.868729602876517, "MEPOLIZUMAB": 32.75679986943822, "METHOTREXATE": 1.507429217409368, "NAGLAZYME": 1.2135409471077707, "NUCALA": 29.15553155286551, "OMALIZUMAB": 20.348422047350333, "ONBREZ": 9.563891615487076, "ORENCIA": 1.8999909169072708, "PANTOPRAZOLE": 2.3572900076589955, "PREGABALIN": 1.0029292583186016, "RELVAR": 6.960243949973473, "RITUXIMAB": 1.313419136456114, "RUCONEST": 1.0227159953620308, "SEEBRI": 14.51042168383211, "STEROIDS": 1.9417619801399235, "SYNAGIS": 1.4819849891220802, "TELMISARTAN": 2.969908944251255, "TEZSPIRE": 32.77069085038518, "TOBRAMYCIN": 1.4944138590906235, "TRELEGY": 3.352290362705897, "UMECLIDINIUM": 47.22364410200125, "UNSPECIFIED": 1.1656062820386075, "VARENICLINE": 5.304440306669286, "XOLAIR": 17.399260804877425, "ZOSTAVAX": 1.1023669278086576, "null": 1.3329800897901791}
\ No newline at end of file
+{"BEOVU": 451.4766247129453, "BROLUCIZUMAB": 657.2409346490258, "EYLEA": 218.05391238939964, "JETREA": 172.84936584715766, "null": 2.29835955331926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7110.json
index cf416bfbcac..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7110.json
@@ -1 +1 @@
-{"HEPSERA": 1245.135526670312}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7111.json
index cc3b9703ec0..41651713749 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7111.json
@@ -1 +1 @@
-{"ELIQUIS": 6.94316828208914, "PLAVIX": 13.70401063190136, "null": 1.8224685290131748}
\ No newline at end of file
+{"null": 0.9124907343506812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7112.json
index 7f56167e691..fb041adc4b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7112.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 6.3585421998165375, "ELIQUIS": 16.144603610326744, "HEMLIBRA": 44.88643496986472, "INLYTA": 12.302893054259268, "LIXIANA": 13.868630299621929, "PLAVIX": 8.94223423357372, "SUTENT": 4.499243594438481, "VOTRIENT": 7.647369860480371, "XARELTO": 49.003750226858166}
\ No newline at end of file
+{"GARDASIL": 15.272774129780249, "SPIKEVAX": 1.970755882107228, "VAXZEVRIA": 1.362156650559429, "null": 0.4878248855918947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7113.json
index 11ed0541d67..313a8a66b99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7113.json
@@ -1 +1 @@
-{"null": 1.2782787144697587}
\ No newline at end of file
+{"null": 0.7011289212253213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7114.json
index c97db9944e4..9c71e5953a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7114.json
@@ -1 +1 @@
-{"null": 1.0688549701826997}
\ No newline at end of file
+{"BOSULIF": 49.67300396486864, "COMIRNATY": 0.1837471622320127, "ZOSTAVAX": 59.21583281840834, "null": 0.7861302917199287}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7115.json
index fc413ff40db..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7115.json
@@ -1 +1 @@
-{"ABACAVIR": 24.746920393446317, "null": 2.3287349339975547}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7116.json
index ad73542805b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7116.json
@@ -1 +1 @@
-{"ACE": 4.018657817045645, "ACTOS": 1.8264383107556144, "ADEFOVIR": 7.132376516903422, "ADENURIC": 2.392078854808924, "AFINITOR": 1.8588149616317364, "ALEMTUZUMAB": 1.3971194011532946, "ALIMTA": 3.1511603449487717, "AMIKACIN": 2.0960871129045366, "AMINOSALICYLIC": 1.1369697902257043, "ANIDULAFUNGIN": 3.5051184866331315, "APROVEL": 1.2566061905652577, "ARANESP": 1.289056345275341, "ATRIPLA": 6.522784237835131, "AVASTIN": 1.044353593217247, "AXITINIB": 1.1987081736985912, "AZACITIDINE": 1.0873503553565256, "AZTREONAM": 2.0553352644625478, "BARACLUDE": 3.99065945160717, "BASILIXIMAB": 5.443871015433787, "BAVENCIO": 1.7784301255652206, "BEVACIZUMAB": 1.2988790540398196, "BIKTARVY": 2.327615898201357, "BLINATUMOMAB": 2.636632530573024, "BOCEPREVIR": 1.6409978568794137, "BONVIVA": 1.9416358329971997, "BORTEZOMIB": 1.3243123188367414, "BOSULIF": 3.570605202432416, "BOSUTINIB": 3.043174614951503, "BRAFTOVI": 2.7166103437945743, "BUMETANIDE": 5.614002666269199, "BUSULFAN": 1.3183551852155333, 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1.4455535492380616, "ZEPATIER": 1.5239153486189476, "ZOMETA": 1.2585419862522214, "null": 1.1112858048233842}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7117.json
index c41b7d1017c..4d82d8d1544 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7117.json
@@ -1 +1 @@
-{"null": 3.500561233185535}
\ No newline at end of file
+{"ATRIPLA": 3.825373136208016, "BIKTARVY": 48.03791963540094, "BUMETANIDE": 111.1047198134594, "BUPIVACAINE": 44.5809742368354, "COMIRNATY": 0.0888611111809712, "COSENTYX": 3.2060588094987112, "FORSTEO": 4.577759645746135, "HUMALOG": 1.6626584563922986, "JANUMET": 4.260128553744752, "TRUVADA": 2.290670895721512, "XELJANZ": 2.5026777763014394, "ZOSTAVAX": 21.521156389006464, "null": 0.8181856046548059}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7118.json
index 4517a922785..357d2da8086 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7118.json
@@ -1 +1 @@
-{"ELIQUIS": 4.134741684747003, "VAXZEVRIA": 1.1393482632485106}
\ No newline at end of file
+{"ATRIPLA": 4.7439487263185, "CABOMETYX": 4.972312336121661, "COMIRNATY": 0.0326503518992149, "COSENTYX": 4.871459228271419, "CYMBALTA": 0.9796534116081134, "EVENITY": 76.62288260096102, "EVISTA": 28.90561504067764, "FORSTEO": 20.522031982771782, "HUMALOG": 1.2098093648991004, "IBRANCE": 1.1176621317397275, "MEPOLIZUMAB": 3.091340074771621, "MIRABEGRON": 66.75008605453684, "SIMPONI": 1.6383609563773671, "SUTENT": 1.169249414919201, "TEDUGLUTIDE": 131.57213863050626, "TRUVADA": 5.651228708380304, "null": 0.8873853542902587}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7119.json
index d379e460067..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7119.json
@@ -1 +1 @@
-{"ADEFOVIR": 3.734831100977009, "ATRIPLA": 99.81318656530578, "ENTECAVIR": 1.010925810454812, "GENVOYA": 1.2919026289344742, "INVOKANA": 2.2548012230903014, "KALETRA": 8.145178035217796, "STRIBILD": 25.85561510833812, "TENOFOVIR": 1.036809292081216, "TRUVADA": 42.92517582116043, "VIREAD": 16.73859373631145}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/712.json
index 9665c5e6c6f..1776a95423d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/712.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/712.json
@@ -1 +1 @@
-{"GARDASIL": 30.20561878252772}
\ No newline at end of file
+{"null": 6.244641060353657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7120.json
index 422800255ed..c22c6fb72f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7120.json
@@ -1 +1 @@
-{"MIDAZOLAM": 56.07505156395093}
\ No newline at end of file
+{"COMIRNATY": 0.5813163717616175, "ZOSTAVAX": 23.402861108902343, "null": 0.324221252742902}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7121.json
index fe1ee4cebfb..bc879498c24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7121.json
@@ -1 +1 @@
-{"AFINITOR": 5.28680995128321, "APIXABAN": 17.559682644444635, "ASPARAGINASE": 11.9801263927708, "ATRIPLA": 5.437195601084016, "AZATHIOPRINE": 34.59938186326724, "CICLOSPORIN": 6.632554570557144, "INLYTA": 8.194431613520164, "JANUVIA": 4.9056993141748535, "LANTUS": 2.236645973930348, "STELARA": 4.941227626071204, "TRUVADA": 1.4458166141523148}
\ No newline at end of file
+{"BEDAQUILINE": 17.16613767832352, "CICLOSPORIN": 3.2674348308150583, "DEXAMETHASONE": 6.031565404396231, "KEYTRUDA": 4.362993419929228, "NEXAVAR": 3.4396696421049247, "PEGASYS": 2.005352668416377, "ROACTEMRA": 9.556916234759017, "SUTENT": 1.3102025816924356, "VOTRIENT": 4.449351553035297, "null": 0.8380843607948769}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7122.json
index 73dbe9bcde0..4665e761a66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7122.json
@@ -1 +1 @@
-{"ATRIPLA": 1.6737145000803586, "LANTUS": 2.047031086281009, "OMALIZUMAB": 13.810943766533995, "STELARA": 5.623926697634691, "SUTENT": 1.3433476551169348, "VOTRIENT": 10.66152154585468}
\ No newline at end of file
+{"ALIMTA": 7.515945786741905, "AUBAGIO": 2.928485174599576, "BEVACIZUMAB": 6.659046596737889, "CELLCEPT": 3.391513991292391, "CIMZIA": 2.7853411413752327, "COMIRNATY": 0.0724457365579387, "DABRAFENIB": 25.76589602633331, "DOCETAXEL": 14.32010390380113, "ELIQUIS": 0.8882128939704915, "FORSTEO": 2.414260537036764, "GEFITINIB": 47.32440281927434, "LUMYKRAS": 247.78417504984668, "MEKINIST": 20.58901489986512, "METHOTREXATE": 3.4559511212375784, "OLYSIO": 28.043911661689865, "PEMBROLIZUMAB": 8.449394920990414, "PEMETREXED": 86.98840776426681, "ROACTEMRA": 9.562035404477918, "SIMPONI": 6.313266472185103, "SOTORASIB": 136.47393837646254, "STELARA": 7.667473539769269, "XALKORI": 44.00791185422814, "XOLAIR": 5.475644854129506, "null": 0.4021035891115588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7123.json
index 6e93f4133a5..01c87149683 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7123.json
@@ -1 +1 @@
-{"null": 1.1646108727749316}
\ No newline at end of file
+{"GEFITINIB": 369.3220082985871, "MEKINIST": 47.43117599142408, "PEMETREXED": 142.9284234042745, "XALKORI": 85.52356478007565, "null": 0.181317598037235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7124.json
index 397b4d70859..8753f67a250 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7124.json
@@ -1 +1 @@
-{"ATRIPLA": 1.1268431682073965, "AZATHIOPRINE": 1.386048479380944, "BENLYSTA": 2.015184507114773, "BIKTARVY": 1.1528845805335977, "CHAMPIX": 1.7124206032208669, "COMIRNATY": 1.4075707374608184, "COVID19": 3.278995172710572, "CRIXIVAN": 13.240787367702504, "EXFORGE": 1.235407096635163, "FORSTEO": 3.127244615048202, "FORXIGA": 2.497374721450217, "JARDIANCE": 2.7928861628447725, "PEGASYS": 1.0216862880730633, "PRIVIGEN": 1.151975297746309, "REYATAZ": 3.8921833196092233, "SPIKEVAX": 1.7661047885598535, "STRIBILD": 1.4255560022005265, "TOVIAZ": 1.1295182672534247, "TOZINAMERAN": 1.72681191917592, "TRUVADA": 1.2759892366663232, "VAXZEVRIA": 1.6866708535813677}
\ No newline at end of file
+{"null": 0.7330776708644279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7125.json
index d0d9bc637f7..84d9275fd5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7125.json
@@ -1 +1 @@
-{"null": 1.0692175350699895}
\ No newline at end of file
+{"COMIRNATY": 0.1036240898930889, "ELIQUIS": 4.464839597472528, "LANTUS": 1.8324462663074084, "NEXAVAR": 2.8190849298960323, "NPLATE": 11.467003295264314, "STELARA": 3.664227465656436, "XALKORI": 23.50581052782383, "null": 0.8978171948148569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7126.json
index d0d9bc637f7..6e76627ee95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7126.json
@@ -1 +1 @@
-{"null": 1.0692175350699895}
\ No newline at end of file
+{"IRESSA": 39.052140692189056, "KEYTRUDA": 6.749178632115048, "null": 1.0654141827020782}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7127.json
index 8e0b908caaf..4fe35f87c69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7127.json
@@ -1 +1 @@
-{"null": 1.1392570241884568}
\ No newline at end of file
+{"null": 3.436105196660173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7128.json
index 263bf13975b..887b2f4d99e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7128.json
@@ -1 +1 @@
-{"VOTRIENT": 65.51764541373763}
\ No newline at end of file
+{"null": 2.0437788875466008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7129.json
index ef1be32c304..9f06fdc1734 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7129.json
@@ -1 +1 @@
-{"APIDRA": 4.630432785192785, "ARANESP": 44.59580225320743, "ATRIPLA": 4.142595447806777, "CICLOSPORIN": 4.454446597115008, "CYMBALTA": 1.0614465887393862, "HUMALOG": 4.1229021445149785, "LANTUS": 19.756837442483185, "LEVEMIR": 7.9629372065228194, "MIMPARA": 47.82512990416674, "SOLIRIS": 18.44691073834847, "TRUVADA": 5.06634876579056, "VELTASSA": 58.12345243109648, "VIREAD": 11.51444411457478, "ZOSTAVAX": 1.7811170928027928}
\ No newline at end of file
+{"ELIQUIS": 4.782978436765554, "TRELEGY": 39.86914384301254, "XELJANZ": 3.836683737473893, "null": 1.8763441920568589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/713.json
index 3cc1f3127e6..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/713.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/713.json
@@ -1 +1 @@
-{"ACLIDINIUM": 1026.0800915136883, "ANORO": 45.99147193150504, "AVAMYS": 78.89471318443336, "CANAGLIFLOZIN": 383.5234770406913, "ENTRESTO": 18.042183582852, "INVOKANA": 89.93854887139695}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7130.json
index 33bf9e72d31..576e587e432 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7130.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 31.615239081221564, "CELLCEPT": 29.06729677770697, "CICLOSPORIN": 87.31339586387926, "MYCOPHENOLATE": 134.16107115004408, "SOLIRIS": 46.31826733669602}
\ No newline at end of file
+{"AFINITOR": 4.912907468524892, "APIXABAN": 10.857578289820168, "BIKTARVY": 20.874198792914715, "CICLOSPORIN": 5.598460646748464, "COMIRNATY": 0.0752768824513981, "CUBICIN": 25.89168983292649, "CYTARABINE": 8.2002024625787, "DEXAMETHASONE": 3.429829749188552, "ENVARSUS": 334.1482293927682, "KEYTRUDA": 2.347179022607832, "LEVOFLOXACIN": 6.120435902584771, "METHOTREXATE": 3.2062222820226856, "NUCALA": 3.351967692458106, "OMALIZUMAB": 8.000287664795426, "PANTOPRAZOLE": 8.571647810844047, "PEMBROLIZUMAB": 7.838807834756025, "SPIKEVAX": 0.5279340452972402, "VAXZEVRIA": 0.151305391766255, "null": 0.7689906140032374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7131.json
index d0f14ca4046..6fe69b7946e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7131.json
@@ -1 +1 @@
-{"ATRIPLA": 4.802415964175574, "EMTRICITABINE": 28.0202350520218, "EXJADE": 14.132654913896944, "HEPSERA": 57.90662626641055, "IBUPROFEN": 9.599299729202498, "JARDIANCE": 2.0410090893963377, "KALETRA": 15.663948247430408, "KEYTRUDA": 2.5978217374799946, "LEVETIRACETAM": 6.02518641997147, "LOPINAVIR": 43.23160786116027, "NORVIR": 32.84003602602806, "SPINRAZA": 16.411660718642572, "TENOFOVIR": 160.38798791436352, "TRUVADA": 5.421255522672472, "VIREAD": 48.93393444774176, "null": 1.0680611272944396}
\ No newline at end of file
+{"DULOXETINE": 72.75252572028427, "null": 0.5498282749676868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7132.json
index c1f45cf7921..8f7a11217a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7132.json
@@ -1 +1 @@
-{"CELLCEPT": 12.533345178055896, "CICLOSPORIN": 46.32015292922189, "MYCOPHENOLATE": 30.744578105931502, "TRUVADA": 2.142987850356737, "null": 1.272882840375935}
\ No newline at end of file
+{"ACLIDINIUM": 1409.8429305547263, "COMIRNATY": 0.5153962223293972, "MEPOLIZUMAB": 45.419413586157255, "null": 0.3738103275227373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7133.json
index c5e9b67b60f..276288f1ee3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7133.json
@@ -1 +1 @@
-{"ATAZANAVIR": 5.917591469883726, "ATRIPLA": 2.699799105229941, "BASILIXIMAB": 15.117970114902938, "CELLCEPT": 5.9969537576087, "CICLOSPORIN": 2.23838692003034, "DOLUTEGRAVIR": 22.02158730724053, "EMTRICITABINE": 12.369877000471435, "EXJADE": 11.188366386069177, "HEPSERA": 98.07129314915124, "INTELENCE": 36.19940474362985, "ISENTRESS": 10.860895955616668, "KALETRA": 10.351320836055802, "NORVIR": 79.18725397218712, "PANITUMUMAB": 35.64491850837888, "STRIBILD": 5.482068065821315, "TENOFOVIR": 435.4851892212097, "TRUVADA": 13.40839534215308, "VIREAD": 58.145386047958354}
\ No newline at end of file
+{"BUDESONIDE": 867.2468798801431}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7134.json
index 3a15246d8cf..e9518ca4a9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7134.json
@@ -1 +1 @@
-{"ABACAVIR": 4.546955439109031, "ATAZANAVIR": 18.067675429419836, "ATRIPLA": 6.675385441387734, "EMTRICITABINE": 57.13217686600649, "EXJADE": 5.08523625607752, "HEPSERA": 103.9915162946266, "STRIBILD": 5.2914957233283, "TENOFOVIR": 371.5404758912924, "TRUVADA": 17.296448026875595, "VIREAD": 178.77414151084986}
\ No newline at end of file
+{"ACLIDINIUM": 155.189601036973, "ESBRIET": 48.39494354424976, "JANUMET": 29.434896013173947, "OFEV": 39.5815663846807, "OMALIZUMAB": 61.34769743867614, "null": 0.658304051207209}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7135.json
index 9e9ae69fbc3..9512d33a570 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7135.json
@@ -1 +1 @@
-{"ATRIPLA": 13.385763089139475, "BUSULFAN": 49.40772620954456, "CICLOSPORIN": 11.538938045787262, "TRUVADA": 5.101837965715749}
\ No newline at end of file
+{"ABATACEPT": 3.8649957690811534, "ACLIDINIUM": 7.157501990190728, "ACTOS": 1.998092169442468, "ADALIMUMAB": 1.0639849273133932, "ADCIRCA": 1.221954270660982, "ADEMPAS": 1.3589690834370551, "AERIUS": 1.1594926475146252, "AFINITOR": 4.942460990996539, "AIMOVIG": 0.1813878398710244, "ALEMTUZUMAB": 0.5570577841912129, "ALIMTA": 4.001933990182212, "AMIKACIN": 1.5003914321856708, "AMINOSALICYLIC": 2.213670110821123, "ANAKINRA": 1.8217842696751176, "ANORO": 28.637294936027303, "ANTIBIOTICS": 5.23722881344897, "APIDRA": 1.0530850150403015, "APIXABAN": 3.6742472571685, "APREMILAST": 0.8754662693188346, "ARANESP": 0.3152500505399811, "ARAVA": 0.6646654170637551, "AUBAGIO": 0.4606125930697235, "AVAMYS": 1.788456563813282, "AVANDAMET": 0.8240702762579647, "AVANDIA": 1.10783323620077, "AVASTIN": 0.9761509789468972, "AZACITIDINE": 1.2272857813090707, "AZATHIOPRINE": 3.140011776837567, "BENLYSTA": 2.7979213404805585, "BENRALIZUMAB": 3.668075840188554, "BEVACIZUMAB": 0.3430447339823361, "BIKTARVY": 0.7845127656600632, "BLINATUMOMAB": 3.920680176271511, "BOSULIF": 1.0911235387059683, "BOTULINUM": 1.3502527665197837, "BRAFTOVI": 0.588653698169819, "BUDESONIDE": 5.616732655022334, "BUPIVACAINE": 3.1607007867345662, "BUSILVEX": 5.911660749875731, "BUSULFAN": 2.366287194491968, "BYDUREON": 0.6195340567741948, "BYETTA": 0.5232577721956159, "CABOMETYX": 0.7252207811911148, "CANAGLIFLOZIN": 6.615561781279364, "CANCIDAS": 1.5052669009477375, "CELLCEPT": 3.913320349297589, "CHAMPIX": 0.2452952689148834, "CICLOSPORIN": 1.167940185050885, "CIMZIA": 1.6898639328384657, "CLOPIDOGREL": 0.6398746511461598, "COMIRNATY": 0.2052082285271715, "COSENTYX": 1.4840266989258246, "COTELLIC": 1.6502942058477852, "CUBICIN": 4.417513773850411, "CYMBALTA": 0.171525439906332, "CYTARABINE": 1.0484727204406583, "DARZALEX": 0.954478460216168, "DEXAMETHASONE": 1.1459567982907892, "DOCETAXEL": 0.6128012643822427, "DOXORUBICIN": 1.4575522219790231, "DUAKLIR": 25.7133939444531, "DULOXETINE": 0.5180509525348693, "ELIQUIS": 1.3146430517729468, "EMEND": 1.694168074813751, "ENBREL": 1.6581420298899647, "ENTRESTO": 0.5833052560094298, "ENTYVIO": 0.5237844146328502, "ESBRIET": 4.761097913472248, "ESOMEPRAZOLE": 1.0241942816860126, "EVEROLIMUS": 2.732633687773769, "EXFORGE": 0.9759708061602538, "EXJADE": 0.7323498211317468, "FASENRA": 4.142563256087541, "FASLODEX": 1.7875962601945887, "FENTANYL": 0.3472457263243707, "FILGRASTIM": 2.136088260073278, "FLUTICASONE": 1.5787119689622724, "FORSTEO": 1.690385773998012, "FORXIGA": 0.2930811453643092, "FULVESTRANT": 0.5546094550942392, "GARDASIL": 0.1488628773272405, "GLIVEC": 1.2407863057595363, "HARVONI": 0.9420720257041344, "HERCEPTIN": 1.743040526496706, "HIZENTRA": 1.0994646838999225, "HUMALOG": 0.9240247058948322, "HUMAN": 0.6451804482257942, "HUMIRA": 0.8533925331130299, "HYDROCORTISONE": 0.6906513333117225, "IBRANCE": 1.7861211378535424, "IBUPROFEN": 0.5757681478397033, "ICLUSIG": 1.066173607511597, "IMATINIB": 3.393466268690392, "INCIVO": 0.3928510081548966, "INCRUSE": 5.439000893572809, "INFLECTRA": 3.759769761536471, "INLYTA": 1.5696988295561316, "INSULIN": 0.3147457402667115, "INVOKANA": 1.5534149147312526, "IPILIMUMAB": 0.8554056164782609, "IRESSA": 26.01572389184868, "JAKAVI": 1.315111099302784, "JANUMET": 1.173715888401982, "JANUVIA": 0.6011782673778124, "JARDIANCE": 0.2186477293891933, "JEVTANA": 0.8864256224171481, "KAFTRIO": 3.6277272346820846, "KALYDECO": 2.422095250119124, "KEPPRA": 0.395282283020465, "KEYTRUDA": 3.413939138167724, "KISQALI": 0.7483975938163233, "KYPROLIS": 0.9913742511396468, "LANTUS": 1.220551761807321, "LEVOFLOXACIN": 0.3825693020771335, "LONSURF": 1.170069603732374, "LYNPARZA": 1.083828968846031, "LYRICA": 1.3728539512037323, "MABTHERA": 3.182178222229484, "MEKINIST": 0.8786912696535985, "MEPOLIZUMAB": 1.8056986803259216, "METHOTREXATE": 1.9600545639933449, "MICARDIS": 0.7767468832988695, "MIDAZOLAM": 0.5259605612708883, "MULTAQ": 2.1862765197534446, "MYCOPHENOLATE": 1.2813524863829453, "NAGLAZYME": 2.11455468526692, "NEULASTA": 0.8827737206896079, "NEXAVAR": 1.1157636486083746, "NOT": 0.8742896645298494, "NOXAFIL": 1.102915906692406, "NPLATE": 0.5314484707471377, "NUCALA": 3.49290543152562, "OFEV": 4.593783756963166, "OMALIZUMAB": 4.268096113397694, "OPDIVO": 1.8438958441089168, "OPSUMIT": 2.102593743014016, "ORKAMBI": 5.239077716003076, "PANTOPRAZOLE": 2.054796345587766, "PEGASYS": 0.7243988923754252, "PEGINTRON": 0.5682089757905662, "PEMBROLIZUMAB": 0.9327717368939806, "PLAVIX": 0.7245939888813214, "PRADAXA": 3.127806483717644, "RAPAMUNE": 4.832913912794032, "RASILEZ": 0.964888312224091, "REBETOL": 1.4368781110971012, "REVATIO": 6.41020708266104, "RINVOQ": 1.8962170534119955, "RITUXIMAB": 0.896393195741287, "ROACTEMRA": 2.0683012289970253, "SILDENAFIL": 0.67712110227694, "SIMPONI": 1.4991099313014495, "SOLIRIS": 1.1936641833085433, "SPIKEVAX": 0.1599683582684085, "SPINRAZA": 1.1972765580339542, "SPRYCEL": 2.0759857588599435, "STELARA": 0.5902881924418161, "STIVARGA": 0.6474159243559302, "SUBOXONE": 0.5503837768707261, "SUTENT": 1.1912030857797713, "SYNAGIS": 3.5149700029506, "TAGRISSO": 8.477348622658056, "TAMIFLU": 1.0328881178909912, "TASIGNA": 1.000154194526616, "TAXOTERE": 2.001515387755858, "TOBRAMYCIN": 2.7022443059056065, "TORISEL": 2.6034988999078728, "TOZINAMERAN": 0.3499045513296624, "TRACLEER": 2.384226814777129, "TRELEGY": 7.438562519042331, "TRULICITY": 0.2639332691504805, "ULTIBRO": 12.398510233168937, "VAXZEVRIA": 0.0840894506900138, "VELTASSA": 1.207571731866586, "VFEND": 2.878510798951254, "VIAGRA": 0.5677004676056475, "VICTOZA": 0.356985922053147, "VORICONAZOLE": 0.6361235426899693, "VOTRIENT": 1.5532618179698474, "XALKORI": 1.6731233281301467, "XARELTO": 0.6063877879367344, "XELJANZ": 2.7142895024184552, "XOLAIR": 2.1207053982336586, "XTANDI": 0.3898634511361383, "ZOSTAVAX": 0.7871406742330671, "ZYPREXA": 0.3258653749507946, "null": 1.127942250876686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7136.json
index bff117d722e..f188cf2d984 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7136.json
@@ -1 +1 @@
-{"ABACAVIR": 1.1625340239041704, "ALIMTA": 4.194583772143596, "AMIKACIN": 3.884189364934071, "APROVEL": 5.4779854899645, "ASPARAGINASE": 2.8616712700174745, "ATAZANAVIR": 7.597994325723877, "ATRIPLA": 3.3588853086579697, "AVASTIN": 1.5236787325633645, "BASILIXIMAB": 27.10429770032339, "BYETTA": 2.024606950689963, "CELLCEPT": 4.146296729341907, "CELSENTRI": 24.838953255165272, "CICLOSPORIN": 3.870891827661013, "CUBICIN": 3.827711585342008, "EFAVIRENZ": 3.957310258464496, "EMTRICITABINE": 10.414453272042175, "ENTRESTO": 1.2351698576095835, "EPIVIR": 8.437768423092422, "EXJADE": 3.0605772355299328, "FEBUXOSTAT": 12.729132856234658, "IBUPROFEN": 4.597349646826273, "INVOKANA": 6.47294286560612, "IRBESARTAN": 8.814977681348017, "KALETRA": 8.266864373956615, "KEYTRUDA": 1.2261991007066992, "LOPINAVIR": 11.588157897095549, "METHOTREXATE": 1.4769374223935583, "MICARDIS": 2.1123054684252303, "MYCOPHENOLATE": 7.743604056053625, "NORVIR": 6.1356269078419645, "PEGINTERFERON": 1.8501503701571065, "PEMBROLIZUMAB": 8.048350806156884, "PEMETREXED": 13.187362614981147, "RAPAMUNE": 6.262581113414199, "REYATAZ": 7.764222364023111, "SOLIRIS": 2.4225284528929056, "STRIBILD": 2.957742685840929, "TACROLIMUS": 6.980908071945522, "TENOFOVIR": 22.580582914456304, "TOBRAMYCIN": 76.80143955603143, "TRUVADA": 4.684604416254127, "VIREAD": 23.450904354446305, "null": 1.5576493178305515}
\ No newline at end of file
+{"NUCALA": 425.48306916958666}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7137.json
index fcecd3d2853..9febda30fe0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7137.json
@@ -1 +1 @@
-{"COVID19": 1.0142185974418578, "SUTENT": 3.4076818106792226, "VAXZEVRIA": 1.507645143285043}
\ No newline at end of file
+{"BUMETANIDE": 424.4136683948769, "CLOPIDOGREL": 5.727509883609768, "COMIRNATY": 0.1290028810144536, "DUAKLIR": 1217.8860284739233, "HYDROCORTISONE": 24.093150856118207, "MEPOLIZUMAB": 15.369183205740384, "null": 1.357695773502562}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7138.json
index 744d799ea36..768c33ef59f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7138.json
@@ -1 +1 @@
-{"null": 2.848173647013041}
\ No newline at end of file
+{"AFINITOR": 8.935591502222245, "ALEMTUZUMAB": 3.723162305538428, "ALIMTA": 2.6404197018067697, "ARAVA": 0.6533879570829909, "AVAMYS": 1.8622952406807805, "AVANDIA": 0.6605431947369875, "AZACITIDINE": 3.9712134913622257, "AZATHIOPRINE": 3.56363512797919, "BASILIXIMAB": 7.891247692447439, "BEVACIZUMAB": 2.121470288677168, "CELLCEPT": 1.0804754891297854, "CICLOSPORIN": 6.965519652775729, "CLOPIDOGREL": 0.7490414867546298, "COMIRNATY": 0.1189337395745978, "CUBICIN": 36.95154364665658, "CYTARABINE": 2.60844876134563, "DEXAMETHASONE": 2.7649954668906016, "EFAVIRENZ": 3.808346992907371, "EPIVIR": 5.115284128498868, "EVEROLIMUS": 13.40256776412486, "EXJADE": 4.858509247715617, "FASENRA": 1.914201420516987, "GANCICLOVIR": 4.149060361502943, "HERCEPTIN": 3.122007351119766, "HUMIRA": 1.029526571661324, "IBUPROFEN": 2.0594952091627805, "IRESSA": 2.9293397521386213, "JAKAVI": 1.6296520193637654, "JANUMET": 0.8141979989893637, "KEYTRUDA": 1.219938954061146, "LAMIVUDINE": 6.108716639535079, "LEVOFLOXACIN": 1.4524497973452248, "MABTHERA": 4.979017783483184, "METHOTREXATE": 1.2540872585973146, "MULTAQ": 5.005714737087952, "MYCOPHENOLATE": 4.099191160928856, "NEULASTA": 5.287983497370491, "NEXAVAR": 0.8439834540088033, "NPLATE": 2.1311599455599515, "OLANZAPINE": 0.957830523711247, "OPSUMIT": 0.6166456232031315, "PEGASYS": 1.1442493664471332, "PEGINTERFERON": 3.349489498541369, "PEGINTRON": 3.834235648844026, "PEMBROLIZUMAB": 1.5585502807210374, "PLAVIX": 0.3769727030530548, "PRIVIGEN": 2.659002016273301, "RAPAMUNE": 11.90821688888021, "ROACTEMRA": 1.0537578917050765, "SOLIRIS": 1.2429854159696343, "SPIKEVAX": 0.5921110984105835, "SPRYCEL": 4.6469046727646095, "STIVARGA": 0.9634638559680784, "SUTENT": 0.3721126527496477, "TAGRISSO": 2.1073581419576777, "TAMIFLU": 1.4895411487662205, "TASIGNA": 1.7286790489608608, "TORISEL": 20.929469791936743, "TOZINAMERAN": 0.1623242881056825, "TRACLEER": 2.5948201457208384, "VAXZEVRIA": 0.0292729181431196, "XOLAIR": 1.9516597146738988, "ZIAGEN": 9.54455091703132, "null": 1.4062127171338634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7139.json
index 63b4cb838b7..77b6ebe177c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7139.json
@@ -1 +1 @@
-{"CICLOSPORIN": 54.98110614762541}
\ No newline at end of file
+{"INTELENCE": 392.0162968566276, "TRELEGY": 43.80134819390682, "null": 1.7783859947453604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/714.json
index f08117c0b3a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/714.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/714.json
@@ -1 +1 @@
-{"AVAMYS": 15.104651158862383, "BENLYSTA": 1.0658970927586664, "BUDESONIDE": 5.277310821590377, "FASENRA": 17.05462748923231, "FLUTICASONE": 13.764111132203649, "GLYCOPYRRONIUM": 14.8907051112214, "HYDROCORTISONE": 3.7077742899266433, "MEPOLIZUMAB": 25.428405385345503, "NUCALA": 56.63213649759543, "OMALIZUMAB": 3.3839733280445805, "RELVAR": 30.26217356100068, "XOLAIR": 15.189563851014636, "null": 2.775888565712766}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7140.json
index 8f83eece06a..6cca930d92e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7140.json
@@ -1 +1 @@
-{"null": 2.3042411770069817}
\ No newline at end of file
+{"ACLIDINIUM": 206.0748539316517, "AFINITOR": 6.286650000726438, "COMIRNATY": 0.0568920595719582, "ELIQUIS": 1.7520183897543866, "ESBRIET": 11.488269917644, "NEXAVAR": 3.069204360384449, "ROACTEMRA": 8.880047599612354, "STELARA": 2.5747941435145405, "VOTRIENT": 9.266638596664054, "null": 0.7646761151221094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7141.json
index 0b482efae82..68137d55a8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7141.json
@@ -1 +1 @@
-{"RASILEZ": 277.7919181710361, "null": 2.082308837258158}
\ No newline at end of file
+{"ACLIDINIUM": 21.55655238078973, "AFINITOR": 0.6237519544475182, "ALIMTA": 1.4668906547525056, "ANORO": 9.88570216641368, "ARANESP": 1.0154563170851676, "ARAVA": 0.0888516165368675, "AUBAGIO": 0.6447479051587298, "AVAMYS": 1.9940110731050364, "BENLYSTA": 0.459683170651438, "BYDUREON": 0.7620526747983843, "BYETTA": 0.7226672756462269, "CELLCEPT": 1.2421832165319833, "CHAMPIX": 1.0577484808014188, "CICLOSPORIN": 0.42262032216569, "CIMZIA": 1.598595020472366, "COMIRNATY": 0.0392690467747767, "COSENTYX": 0.9596903276637726, "CYMBALTA": 0.1263900339250719, "DEXAMETHASONE": 0.968789166848446, "DOCETAXEL": 0.6407173190352459, "DOXORUBICIN": 1.6990881186361764, "ELIQUIS": 2.7436734898242974, "ENBREL": 0.5265778178625019, "ENTRESTO": 0.3429813303203768, "ENTYVIO": 0.7670084853464081, "EPADERM": 75.57418514590347, "ESBRIET": 5.6284134464195965, "EVENITY": 2.529412716010654, "EXFORGE": 0.8204820918444788, "EYLEA": 0.6014542850895049, "FASENRA": 0.9125590290515876, "FASLODEX": 0.7851548224214322, "FEBUXOSTAT": 3.855896899204271, "FIRDAPSE": 2.565299176101854, "FORSTEO": 2.439717162561026, "HUMALOG": 1.083170127857188, "HUMIRA": 0.3183782094937128, "IBRANCE": 0.630546708895834, "INCRUSE": 13.09634456805191, "INLYTA": 0.8055628934675875, "INSULIN": 0.5432879622764007, "IRESSA": 3.717607999085944, "JAKAVI": 2.003059686613432, "JANUMET": 1.947802955562211, "JANUVIA": 0.8585901261659213, "JARDIANCE": 1.0990744259294245, "KEYTRUDA": 0.6363193264803533, "LANTUS": 1.909551868677446, "LEVEMIR": 1.7816887902801286, "LYRICA": 0.3712939597872563, "MEKINIST": 7.522788296753413, "MEPOLIZUMAB": 1.3526463093232473, "METHOTREXATE": 0.6732751739048323, "MICARDIS": 2.2353341957195973, "NEULASTA": 2.067877888086081, "NEXAVAR": 0.2794810900233243, "NPLATE": 3.222570331459524, "NUCALA": 0.6652503805063456, "OFEV": 5.500278878535834, "OLANZAPINE": 0.2416981113952766, "OPSUMIT": 1.283129607727063, "PEGASYS": 0.6123480584717822, "PEGINTRON": 0.403928830664932, "PLAVIX": 0.784396818135078, "RAPAMUNE": 3.044617178879164, "RELVAR": 2.670035907621879, "REVATIO": 3.0276096328834146, "REVLIMID": 1.6416352860591632, "RINVOQ": 2.67159446348705, "ROACTEMRA": 2.062580386261799, "SIMPONI": 2.168795526601157, "SKYRIZI": 3.078402096828841, "SOLIRIS": 0.4000491506830749, "SOTORASIB": 12.518128619614066, "SOVALDI": 2.0633085005915626, "SPIKEVAX": 0.0313556298605688, "SPRYCEL": 1.1618315142106272, "STELARA": 2.395416439480274, "SUTENT": 0.399541618550458, "TAGRISSO": 8.157281600255411, "TASIGNA": 1.1450031940762244, "TOVIAZ": 0.9505253132378286, "TOZINAMERAN": 0.0935497151473236, "TRACLEER": 1.8388239591616429, "TRELEGY": 27.359607352096564, "TREMFYA": 1.5183164196531136, "TRULICITY": 0.639261429354729, "VAXZEVRIA": 0.0264994525948349, "VELTASSA": 1.3520838440406124, "VFEND": 1.8337834023712984, "VIAGRA": 1.9152148378924725, "VOTRIENT": 1.2550366824903745, "XALKORI": 65.06347904480481, "XELJANZ": 2.9999283977820266, "XOLAIR": 2.021281790340965, "XTANDI": 1.3154407105801351, "ZOSTAVAX": 0.9636533798920518, "ZYPREXA": 0.1629308704373217, "null": 2.648982800353088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7142.json
index 565444e1db9..9c21761c4fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7142.json
@@ -1 +1 @@
-{"null": 1.2574723005795418}
\ No newline at end of file
+{"null": 0.5610331033905649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7143.json
index 4fcc6493667..f4f1c9899f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7143.json
@@ -1 +1 @@
-{"ANGIOX": 2923.133191845433}
\ No newline at end of file
+{"ADENURIC": 13.708019745625666, "AFINITOR": 6.2941644758001, "AVAMYS": 15.643231400079603, "BENRALIZUMAB": 15.667178966294692, "BUDESONIDE": 24.29828124766906, "BUSULFAN": 4.044633786583161, "CABOMETYX": 3.098085346602238, "COMIRNATY": 0.267457902318142, "CYMBALTA": 0.610050340187585, "CYTARABINE": 6.036730017482625, "DEXAMETHASONE": 5.419739081198364, "GANCICLOVIR": 8.68872095946977, "IBRANCE": 1.1731210600301418, "JANUMET": 4.107336517737529, "KEYTRUDA": 7.04647066693587, "MEKINIST": 2.347223800017273, "MEPOLIZUMAB": 3.5188333123903286, "NUCALA": 4.19963633319571, "OPDIVO": 4.340232951173019, "PANTOPRAZOLE": 8.597636545712723, "RINVOQ": 4.76851561153506, "RITUXIMAB": 2.0066910035925734, "SPIKEVAX": 1.887125730990236, "TAGRISSO": 22.832835082362784, "TOZINAMERAN": 0.3607031178851219, "VAXZEVRIA": 0.0662052124750797, "null": 0.5514411876040988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7144.json
index 01f99b80b03..8e6d2386488 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7144.json
@@ -1 +1 @@
-{"null": 3.1422521573791133}
\ No newline at end of file
+{"TRELEGY": 22.896485722515365, "VOTRIENT": 10.66369760815222, "null": 2.43323524571882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7145.json
index cb4c8ceb16c..9dbd25a1986 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7145.json
@@ -1 +1 @@
-{"OCEAN": 10922.780900207154}
\ No newline at end of file
+{"null": 0.6770567443997207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7146.json
index 860525ffd0b..9d2592bc8d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7146.json
@@ -1 +1 @@
-{"null": 1.7979132684275714}
\ No newline at end of file
+{"RINVOQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7147.json
index 1ad0469688b..679432d3c27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7147.json
@@ -1 +1 @@
-{"null": 3.442779540174401}
\ No newline at end of file
+{"BOSENTAN": 75.37673154476656, "KALYDECO": 84.26020092909432, "OFEV": 51.13058623378122, "OPSUMIT": 114.27154895923174, "ORKAMBI": 112.21702162275216, "TRACLEER": 101.10920016670671, "null": 0.7478936874221271}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7148.json
index 398c9937973..3d31af2e270 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7148.json
@@ -1 +1 @@
-{"TOVIAZ": 467.9031164856961, "null": 2.055622079171876}
\ No newline at end of file
+{"AMIKACIN": 86.75445446744452, "CELLCEPT": 24.77657600980684, "CICLOSPORIN": 70.40711806926723, "MYCOPHENOLATE": 50.09454433237544, "VFEND": 39.83635048862307, "null": 0.3303781835056252}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7149.json
index 75df1f4a725..71f3fa8d30e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7149.json
@@ -1 +1 @@
-{"CELECOXIB": 313.39479916085634, "DEXAMETHASONE": 30.384538905424407}
\ No newline at end of file
+{"AZATHIOPRINE": 22.140087460022627, "BENLYSTA": 167.11274984090224, "CELLCEPT": 13.80984927978921, "CICLOSPORIN": 6.168756866010228, "COMIRNATY": 0.1040650412477429, "CYMBALTA": 1.9766903879715587, "GARDASIL": 2.612345366539917, "LUPKYNIS": 155.4193937872188, "SIMPONI": 7.727969652014015, "TOZINAMERAN": 0.5472306080986333, "null": 0.6213052837368527}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/715.json
index 69007850956..5213f234d69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/715.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/715.json
@@ -1 +1 @@
-{"GARDASIL": 2.9041705346459343, "HUMALOG": 2.738801515105753, "ZOSTAVAX": 19.59830769058446, "null": 2.3834058851159496}
\ No newline at end of file
+{"BUPIVACAINE": 886.3754920505269, "FENTANYL": 103.38249280917366, "null": 0.3357036215565476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7150.json
index 3f539c80b24..0d4f33f246b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7150.json
@@ -1 +1 @@
-{"CIMZIA": 1.895691161804456, "COMIRNATY": 1.1793282003650418, "ESBRIET": 1.7747504609326696, "FENTANYL": 1.676947725520014, "HARVONI": 3.522637375767661, "INSULIN": 15.38942718038784, "MEPOLIZUMAB": 5.897630707723087, "MIDAZOLAM": 4.333224447277258, "MMRVAXPRO": 4.477757732942134, "NUCALA": 3.466113310119357, "OLANZAPINE": 1.5845814448465774, "OMALIZUMAB": 2.9662403606150654, "OPSUMIT": 2.0070066495172165, "ORKAMBI": 45.7458022871807, "SYNAGIS": 4.112746645026419, "TOZINAMERAN": 1.005976320187098, "TRELEGY": 2.2666545938746228, "VAXZEVRIA": 1.12720032181407, "ZOSTAVAX": 1.0167348660447568, "null": 1.107702593820041}
\ No newline at end of file
+{"null": 1.4293166421256611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7151.json
index 8d429ff2974..425edd19760 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7151.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 4.605727059760719, "BUDESONIDE": 1.7823021940821695, "BUPIVACAINE": 7.1224180833274175, "BUPRENORPHINE": 3.0958540336687204, "DEXAMETHASONE": 3.0560990789729097, "FENTANYL": 18.08748117714124, "GLIBENCLAMIDE": 22.66230604191093, "HYDROCORTISONE": 10.074876529457978, "IBUPROFEN": 4.94548005105974, "JARDIANCE": 4.167455347222631, "KEPPRA": 2.0167998514319883, "LACOSAMIDE": 7.003539522978501, "LEVOFLOXACIN": 1.8347907359367357, "MIDAZOLAM": 12.832259779831972, "OLANZAPINE": 3.5412625369690804, "ZYPREXA": 1.7807454920225034, "null": 3.118842580004438}
\ No newline at end of file
+{"null": 0.9518920967503458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7152.json
index 79cb9641cea..8af5445d9a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7152.json
@@ -1 +1 @@
-{"ACTRAPID": 90.13850669911108, "NALOXONE": 399.3790692786419, "null": 2.2176592288517942}
\ No newline at end of file
+{"ABATACEPT": 7.416590058765951, "ADALIMUMAB": 128.46915977709304, "AMINOSALICYLIC": 80.78693278955653, "ARAVA": 2.1040153376664965, "BOTULINUM": 49.24558927342191, "COSENTYX": 12.140345623101894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7153.json
index a96580c3a47..9d4bd7e29a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7153.json
@@ -1 +1 @@
-{"ANGIOX": 10.383147837131364, "ARIPIPRAZOLE": 2.4309440901151875, "AVANDIA": 1.006449049276976, "BENZODIAZEPINE": 15.15325368812598, "BEXSERO": 2.569335674791817, "BRIDION": 19.379620631153827, "BRIVARACETAM": 3.03289447280678, "BUCCOLAM": 27.030711394120697, "BUPIVACAINE": 3.562602185618342, "BUPRENORPHINE": 4.297963865726016, "CASPOFUNGIN": 1.5109979875660418, "CUBICIN": 1.912041311301508, "DEXDOR": 15.698888846479743, "DULOXETINE": 7.058294187611319, "ESOMEPRAZOLE": 1.4506327300994353, "FENTANYL": 13.298781485110222, "GLIBENCLAMIDE": 2.537681922005944, "HYDROCORTISONE": 2.9870040819133936, "IBUPROFEN": 4.829623987025287, "INFANRIX": 1.5020063967621444, "JEVTANA": 1.2551959393384224, "MIDAZOLAM": 12.274701265957283, "MIRCERA": 2.2219640631112245, "NAGLAZYME": 3.7352027350288832, "NALOXONE": 14.68365083925587, "NOT": 7.860429297354565, "OLANZAPINE": 3.744397413722359, "OPIOID": 54.78702525440836, "OXYBUTYNIN": 4.455577458540758, "PREGABALIN": 8.669423627406777, "PREVENAR": 3.918616804685032, "PROPRANOLOL": 11.088074381501512, "REVATIO": 2.112811488233991, "ROTATEQ": 1.3161807133932255, "SILDENAFIL": 4.489935694678202, "SPINRAZA": 8.090625846430132, "STALEVO": 1.5563127483859274, "SUBOXONE": 2.0044390897639754, "SUFENTANIL": 3.5092173992090943, "SYNAGIS": 5.939632004807681, "TAMIFLU": 1.2913769140336264, "TORISEL": 1.7480386180157717, "TRACLEER": 1.4552341557165072, "TRAZODONE": 91.75444738262584, "UNKNOWN": 7.437398555243909, "UNSPECIFIED": 57.9486603798576, "VIMPAT": 1.409156718595191, "XOLAIR": 1.300670598973792, "ZYPREXA": 1.4704151209900047, "null": 3.8915359153201576}
\ No newline at end of file
+{"ABATACEPT": 2.5302788497561126, "ADALIMUMAB": 6.555551656607691, "AIMOVIG": 1.654984885749481, "AMINOSALICYLIC": 8.808402035961873, "ARAVA": 2.1692449270027683, "CELLCEPT": 1.804139473763872, "CICLOSPORIN": 1.0385323724974946, "CIMZIA": 9.277622123897132, "COMIRNATY": 0.0616937033166929, "COSENTYX": 7.120885731730291, "ENBREL": 3.5868098804436146, "ENTYVIO": 11.810202608305971, "GARDASIL": 0.8756006954619842, "HUMAN": 5.194379405222399, "HUMIRA": 18.353483526224924, "LEVOFLOXACIN": 1.2944517367870916, "PEGASYS": 0.5836503057527628, "PEGINTRON": 0.9764013877635956, "REMICADE": 28.574480290719137, "SIMPONI": 12.769318017320208, "SPIKEVAX": 0.0597929568593827, "STELARA": 5.468382778655245, "XELJANZ": 0.890580209792488, "null": 1.3514320430161029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7154.json
index d93c173ec71..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7154.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 8.268090475588757, "BENZODIAZEPINE": 8.277436106554003, "BRIDION": 6.538619963583229, "BUCCOLAM": 166.99216145940065, "BUPIVACAINE": 15.274017276246315, "BUPRENORPHINE": 14.354534020794986, "BUVIDAL": 12.637224958243204, "CYMBALTA": 1.1399596050651046, "DEXMEDETOMIDINE": 28.73982369144186, "DULOXETINE": 5.310389538936418, "FENTANYL": 25.508194642826528, "GLUCAGON": 17.646401564870867, "HYDROCORTISONE": 2.33978335419846, "IBUPROFEN": 1.9865005479102165, "KEPPRA": 1.101883463322228, "LYRICA": 3.5042459945546325, "MIDAZOLAM": 30.651226131331384, "NALOXONE": 18.967529158242627, "OLANZAPINE": 4.45453561669157, "PREGABALIN": 13.005283061050667, "RISPERIDONE": 37.90971896698693, "SUBOXONE": 6.122183007716353, "SUFENTANIL": 21.54729923188729, "XYREM": 8.265027129324123, "ZALVISO": 255.73332124954285, "ZYPREXA": 3.803655832250898, "null": 4.568320571719723}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7155.json
index 89e94e22c97..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7155.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.686928541072215, "VAXZEVRIA": 2.4642960792907016}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7156.json
index b2e7b6bb632..703fd0ca7cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7156.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"ARAVA": 0.8341588420110605, "CLINDAMYCIN": 251.095139031637, "COMIRNATY": 0.6850560613809322, "COSENTYX": 2.4099996140372246, "GARDASIL": 10.666414880869382, "HUMIRA": 4.017516312483463, "SHINGRIX": 3.0737778449555964, "SIMPONI": 2.127427535831008, "SPIKEVAX": 0.7083590749341001, "STELARA": 3.1032576718822846, "TOZINAMERAN": 1.7974070889188989, "VAXZEVRIA": 0.4055379496684368, "XELJANZ": 4.506709309171524, "ZOSTAVAX": 2.683062701924735, "null": 0.7380667719064347}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7157.json
index 4f9d7bf6306..75547da5f54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7157.json
@@ -1 +1 @@
-{"ABATACEPT": 5.856262404865904, "ACLIDINIUM": 13.193316309498613, "ALEMTUZUMAB": 3.144984331877096, "AMINOSALICYLIC": 1.2595671197346046, "ANORO": 3.074412450169052, "ARAVA": 6.309106340480904, "ASPARAGINASE": 1.3746166076315294, "AVAMYS": 1.3798239221843027, "BENLYSTA": 1.879719468877224, "BRIDION": 2.1232046876738657, "BUSULFAN": 2.18439540244822, "CHLORHEXIDINE": 1.4893496646737887, "CICLOSPORIN": 1.226348500588579, "CIMZIA": 1.6588972031764588, "COMBIVIR": 1.8176472749533477, "DARZALEX": 2.398370254602616, "DUAKLIR": 37.45509240286375, "ERENUMAB": 6.717266146899371, "ESBRIET": 3.012641738759477, "FASENRA": 2.146611505602336, "FENTANYL": 1.598037217953141, "FORSTEO": 1.5174550816691152, "GLYCOPYRRONIUM": 4.817130224566473, "HIZENTRA": 1.687956295105067, "HYDROCORTISONE": 4.951970720157633, "IBUPROFEN": 1.0289048435730823, "JANUMET": 1.0195156643505967, "KALETRA": 1.5751613698964275, "KYMRIAH": 1.3881511244244624, "MEPOLIZUMAB": 4.641953314301232, "MIDAZOLAM": 2.538912377895171, "MULTAQ": 1.1710178924557386, "NAGLAZYME": 10.744914177809369, "NOT": 1.1383463640027922, "NUCALA": 2.870849392494544, "OFEV": 2.173575047090299, "OMALIZUMAB": 3.536565114041612, "OPSUMIT": 1.80183101385838, "ORKAMBI": 3.1851075493451675, "PEGINTERFERON": 1.0160456071946615, "PEGINTRON": 1.25464018506442, "RELVAR": 3.514729056504451, "REMDESIVIR": 5.026750708682881, "REVATIO": 1.65943285335186, "SIMPONI": 1.425723365655465, "SPINRAZA": 19.68683494139902, "SYNAGIS": 10.79803298265356, "TOBRAMYCIN": 5.513658245695871, "TRACLEER": 1.4455776955762214, "TRELEGY": 2.1570514190578893, "TREMFYA": 1.1906126990222208, "VEKLURY": 6.433615956628006, "XELJANZ": 1.1614393050664318, "XOLAIR": 3.409257585453896, "null": 1.1792825095049548}
\ No newline at end of file
+{"COMIRNATY": 0.7240947670243933, "TOZINAMERAN": 5.794831361200327, "null": 0.329738704797487}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7158.json
index 550450c6c93..9b4cbe06273 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7158.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 14.351174185680282, "CYMBALTA": 4.110690737252869, "LEVEMIR": 29.521348740205312, "SUBOXONE": 10.604916589382992, "ZYPREXA": 4.234480986408012, "null": 2.588730590460216}
\ No newline at end of file
+{"COMIRNATY": 2.081451209286624, "null": 0.2582626394819432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7159.json
index c60f61c4769..584dc9d4053 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7159.json
@@ -1 +1 @@
-{"ACTRAPID": 1.863750858098035, "ADCIRCA": 2.0510171629656075, "AERIUS": 2.2982164399976583, "ALEMTUZUMAB": 1.185179110674776, "ALIMTA": 1.319447098723156, "AMIKACIN": 3.08836736286121, "AMINOSALICYLIC": 1.0513861482991125, "ASPARAGINASE": 1.981973618736516, "ATOSIBAN": 9.197036250336888, "AVAMYS": 1.3233318202548978, "AZACITIDINE": 2.457462934831252, "BEDAQUILINE": 4.531881974107412, "BRIDION": 1.056271389721633, "BUSULFAN": 2.2399693591287235, "CAELYX": 1.467254827058798, "CANCIDAS": 2.1981751754294296, "CASPOFUNGIN": 2.833815884556932, "CELECOXIB": 1.5647380064713807, "CICLOSPORIN": 1.3466552171838826, "COMBIVIR": 1.663259666416793, "CUBICIN": 2.5035017591251463, "CYTARABINE": 1.3793584317729253, "DARZALEX": 2.640232247015679, "DELAMANID": 2.729394763641804, "DESLORATADINE": 1.9162916418351648, "DEXAMETHASONE": 1.638730398949942, "DINUTUXIMAB": 35.678279929193934, "ESOMEPRAZOLE": 4.006151180557453, "FASENRA": 1.236569743616263, "FENTANYL": 2.4036193541140327, "FILGRASTIM": 1.1958701830639744, "FLEBOGAMMA": 4.014462704988785, "GANCICLOVIR": 1.3370657936594197, "GARDASIL": 2.1280458582157817, "GAZYVARO": 2.094093299040895, "HERCEPTIN": 1.0540449308056046, "HUMAN": 2.239396214724424, "HYDROCORTISONE": 1.0290559831224524, "IBUPROFEN": 1.2567829757432378, "ICLUSIG": 1.286447820656998, "INCRUSE": 1.0378710382170209, "INFANRIX": 1.2523672255282523, "IRON": 5.141985610462714, "ISENTRESS": 4.076777588753494, "JEVTANA": 1.0465744392524112, "KETOCONAZOLE": 5.883485711525176, "KIOVIG": 3.415195640407385, "KYMRIAH": 1.5130396146416305, "LAMIVUDINE": 2.346521605900777, "LEVOFLOXACIN": 1.2137250922966325, "MABTHERA": 1.6810293163658172, "MELPHALAN": 1.9761493218669488, "MERCAPTOPURINE": 1.5100209126041275, "MIDAZOLAM": 4.208192137088547, "MIRCERA": 3.6647258506608034, "MYCOPHENOLATE": 1.896040222555998, "NAGLAZYME": 6.489544160524841, "NOVOSEVEN": 2.664804157544525, "OLANZAPINE": 2.3129881330409603, "ONCASPAR": 3.8703322688822, "OPSUMIT": 1.3145358267951048, "ORKAMBI": 1.5845185626920968, "OSELTAMIVIR": 5.061032356298201, "PERJETA": 2.9171843994845124, "PREVENAR": 1.2800018699981468, "PRIVIGEN": 3.1672357157867705, "REMDESIVIR": 5.0394890505583625, "REVATIO": 2.0080961425870107, "SOLIRIS": 1.3463635826423077, "SPINRAZA": 7.306733321550579, "SYNAGIS": 17.72830835778787, "THALIDOMIDE": 1.2790856299006077, "THIOTEPA": 3.198589154126713, "TOZINAMERAN": 3.590384955898968, "TRACLEER": 2.4865160126474946, "TRACTOCILE": 9.164597783782272, "TRELEGY": 1.0782333437883842, "VAXZEVRIA": 1.1953433664557824, "VORICONAZOLE": 1.022457516922295, "XOLAIR": 2.2562026105387103, "null": 1.7550240765334235}
\ No newline at end of file
+{"COMIRNATY": 8.053124416402467, "GARDASIL": 0.6068416650198423, "MMRVAXPRO": 1.1718952986325148, "MODERNA": 0.8251089159082037, "OCRELIZUMAB": 1.2680342631420898, "SHINGRIX": 0.4044201361628576, "SPIKEVAX": 3.1556327160657536, "STELARA": 0.2443543600379476, "TOZINAMERAN": 5.288439347754957, "VAXZEVRIA": 1.1164198592649794, "null": 0.0414744803712835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/716.json
index 64847ef6b17..6fd6a53b2c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/716.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/716.json
@@ -1 +1 @@
-{"null": 1.778923614366971}
\ No newline at end of file
+{"COMIRNATY": 0.1994764156988851, "null": 1.8927559143340889}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7160.json
index 0dd369cde86..38b07a22490 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7160.json
@@ -1 +1 @@
-{"ACTRAPID": 24.605239513214, "ADCIRCA": 2.3920959822605607, "ADEMPAS": 2.543380793187238, "AFINITOR": 1.499178228381959, "ALEMTUZUMAB": 3.969103482953472, "ALENDRONIC": 27.31797610905545, "ALIMTA": 2.773193481391213, "AMIKACIN": 3.229233495176351, "AMINOSALICYLIC": 7.279521893177401, "ANGIOX": 4.718220597819974, "ANIDULAFUNGIN": 4.206649519313346, "ANTIBIOTICS": 2.812617853814052, "APREPITANT": 1.654456617151023, "ASPARAGINASE": 1.825785630854428, "AVANDAMET": 1.7558157908693874, "AVANDIA": 3.0820235222524754, "AVASTIN": 1.2062277477551424, "AXITINIB": 1.112986522366608, "AZACITIDINE": 2.807957313353412, "BASILIXIMAB": 5.231258839369625, "BEDAQUILINE": 11.830108981004244, "BEVACIZUMAB": 1.595052296236744, "BIKTARVY": 1.2520791300656229, "BORTEZOMIB": 2.36130286847538, "BOSENTAN": 5.183862866599906, "BRIDION": 3.797131711417471, "BUPIVACAINE": 1.481264031119209, "BUSILVEX": 2.8659695464173565, "BUSULFAN": 6.7779388582490245, "BYETTA": 1.5640115524475071, "CAELYX": 1.4477428247899369, 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\ No newline at end of file
+{"COMIRNATY": 3.746849550550893, "SPIKEVAX": 1.534383763040153, "TOZINAMERAN": 1.1807742962542556, "VAXZEVRIA": 0.4695210324410751, "null": 0.3115723021338706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7161.json
index fa0b9c847bd..37bf90050e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7161.json
@@ -1 +1 @@
-{"COMIRNATY": 1.890968167408389, "SPIKEVAX": 1.6425360781468783}
\ No newline at end of file
+{"CIMZIA": 7.378427894103275, "JAKAVI": 60.95984945328534, "PEGASYS": 2.949003532312677, "PEGINTERFERON": 27.136394997868923, "PEGINTRON": 6.254891066078447, "SIMPONI": 19.494614275816797, "null": 0.3293497123545772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7162.json
index f0e14bfb87c..124acf565b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7162.json
@@ -1 +1 @@
-{"AVAMYS": 65.02341719943165, "MEPOLIZUMAB": 39.55302457394728, "null": 1.4146754469640113}
\ No newline at end of file
+{"CELLCEPT": 7.572216498761302, "CICLOSPORIN": 16.35904506636284, "COMIRNATY": 0.1153566750448358, "KEYTRUDA": 10.28188284423604, "null": 1.0583357807252525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7163.json
index 6bbbb0970b6..205bf2df432 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7163.json
@@ -1 +1 @@
-{"null": 1.6462750390576275}
\ No newline at end of file
+{"ADALIMUMAB": 0.1167696764785946, "AMIKACIN": 2.9665863224673688, "AZATHIOPRINE": 4.335684203003407, "CICLOSPORIN": 2.141758224836231, "COMBIVIR": 3.043221341082172, "COMIRNATY": 6.982644709416701, "CRIXIVAN": 4.163623707887661, "DOXORUBICIN": 3.108217167269122, "FILGRASTIM": 6.140920595934892, "GARDASIL": 1.498071522904967, "KEPPRA": 0.3150282007096095, "KEYTRUDA": 0.3286496936419164, "LAMIVUDINE": 23.85275776010846, "MENVEO": 4.366706600740012, "MMRVAXPRO": 3.6736761427426448, "MODERNA": 5.819029557824164, "NIMENRIX": 4.068550207702908, "PEGASYS": 0.3061464331210316, "SHINGRIX": 0.4989210572220167, "SPIKEVAX": 1.9332928566007297, "TOZINAMERAN": 1.0923661038941324, "VAXZEVRIA": 0.5747316239669339, "null": 0.2353920178069282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7164.json
index b23ca03e3a1..04df4456f60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7164.json
@@ -1 +1 @@
-{"CELECOXIB": 1255.7592321339732}
\ No newline at end of file
+{"null": 0.7256991417055473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7165.json
index e99ea6ff055..624df2a6ada 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7165.json
@@ -1 +1 @@
-{"null": 7.1189753296775145}
\ No newline at end of file
+{"VFEND": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7166.json
index 4f6d7204cc7..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7166.json
@@ -1 +1 @@
-{"COVID19": 4.4596667087219055}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7167.json
index e51dadefdd1..1cdc4deb0fd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7167.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 5.974765783079768, "FENTANYL": 10.21469051669647, "IBUPROFEN": 3.9286644171193807, "KEPPRA": 2.249677547493772, "LYRICA": 9.05834803322403, "MIDAZOLAM": 6.054903238358053, "OMALIZUMAB": 4.997827755906314, "SUBOXONE": 2.082497981554748, "TOBRAMYCIN": 25.097384826881523, "ZYPREXA": 2.668268690365525, "null": 2.6556527511335397}
\ No newline at end of file
+{"ABACAVIR": 0.1508599718523957, "ABATACEPT": 0.0301107045223029, "ACALABRUTINIB": 5.855002439232344, "ADALIMUMAB": 0.042396661219754, "ADCETRIS": 0.580441653844808, "ADENURIC": 0.2577704419763389, "AFINITOR": 0.2943114342762298, "AIMOVIG": 0.0963728091860299, "ALDARA": 0.6752914462112541, "ALEMTUZUMAB": 0.481430617365127, "AMIKACIN": 0.1453766536654596, "APIXABAN": 0.0270779902993062, "ARAVA": 0.0526220797087521, "ASPARAGINASE": 0.1076732532994137, "ATAZANAVIR": 0.1576441754496161, "ATRIPLA": 0.0070488974093269, "AUBAGIO": 0.0468194905057538, "AVASTIN": 0.1122370459607217, "AZATHIOPRINE": 0.3266833739140227, "BEDAQUILINE": 0.0802843577167342, "BENLYSTA": 0.1965101786930502, "BETAFERON": 0.2466575576774508, "BEVACIZUMAB": 0.1501816224857708, "BRAFTOVI": 0.0918058769482405, "BRINTELLIX": 0.0616645923980515, "BUDESONIDE": 0.0243254907436588, "BUSULFAN": 0.437623503604046, "BYDUREON": 0.3884599189706484, "BYETTA": 0.1996088509475936, "CABAZITAXEL": 1.6214846002674403, "CABOMETYX": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7168.json
index 841dfc9cf02..3c047d7e842 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7168.json
@@ -1 +1 @@
-{"AFINITOR": 3.131303588930069, "BEVACIZUMAB": 1.9875705043383585, "BUDESONIDE": 1.056070323768198, "CLOPIDOGREL": 6.178410266384722, "ESBRIET": 1.9853354968308536, "FASENRA": 1.9280306859860377, "FENTANYL": 1.3718335467826457, "FLEBOGAMMA": 40.62222287428656, "HYDROCORTISONE": 5.505813236962944, "INSULIN": 1.7686841269967115, "KALETRA": 2.125209410227226, "KYMRIAH": 3.822219750053017, "LACOSAMIDE": 6.409744742454692, "LEVOFLOXACIN": 1.2213301593269712, "MEPOLIZUMAB": 2.1421562914260424, "METHOTREXATE": 1.4832553385432763, "MIDAZOLAM": 6.413143645879517, "NAGLAZYME": 5.705635668774408, "OFEV": 3.1611292400371265, "OLANZAPINE": 1.0443592826286872, "OMALIZUMAB": 7.518790513776855, "PRIVIGEN": 14.94566009596618, "RITUXIMAB": 1.549121308000809, "STIVARGA": 1.8941806167938215, "SYNAGIS": 8.809528506131956, "TICAGRELOR": 6.941773923038289, "TOZINAMERAN": 1.247760258730621, "VALSARTAN": 5.760275060467538, "XOLAIR": 5.157380116918331, "null": 1.5034427266927983}
\ No newline at end of file
+{"AFINITOR": 6.463944047692348, "CICLOSPORIN": 5.210481988955803, "CLOPIDOGREL": 3.0650096957908746, "COMIRNATY": 0.2513230331840017, "CYTARABINE": 4.695930233122192, "FASLODEX": 10.970817977116202, "INCIVO": 14.850550416853643, "KEYTRUDA": 3.9611418075168223, "MEPOLIZUMAB": 9.317914272011151, "NEXAVAR": 10.950571625321064, "PEGINTERFERON": 5.910927332641744, "SPIKEVAX": 0.3703319277865876, "STIVARGA": 5.82610558980444, "SUTENT": 0.951584102334667, "VOTRIENT": 3.620643576250691, "null": 0.3284018539766569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7169.json
index 6a649a1f8b4..5d68f82ef05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7169.json
@@ -1 +1 @@
-{"ACLIDINIUM": 41.88759750196953, "ANORO": 199.963374810061, "APIXABAN": 5.799252441255084, "AVAMYS": 4.037465408132624, "AZATHIOPRINE": 16.93933053982527, "BUDESONIDE": 4.248392906182893, "COMIRNATY": 1.05102763299333, "GLYCOPYRRONIUM": 25.36879956410619, "IBUPROFEN": 4.275672549454443, "JANUMET": 4.0501868784724815, "MEPOLIZUMAB": 10.737940061205052, "METHOTREXATE": 17.53513735997219, "MIDAZOLAM": 6.9683458417701365, "NUCALA": 12.58699667424182, "ORKAMBI": 23.92436941742956}
\ No newline at end of file
+{"null": 0.7485510523650343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/717.json
index 46c05587362..b9572141988 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/717.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/717.json
@@ -1 +1 @@
-{"AVASTIN": 32.01138660729955, "TEMOZOLOMIDE": 134.65670303122215, "null": 1.0813730204917706}
\ No newline at end of file
+{"PRIVIGEN": 410.9592757351694, "null": 1.603923508799126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7170.json
index 0a69774544a..129b4122bd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7170.json
@@ -1 +1 @@
-{"SYNAGIS": 12149.277701894092}
\ No newline at end of file
+{"AFINITOR": 35.32482778798121, "AVASTIN": 16.068402141762757, "BEVACIZUMAB": 15.923145554560897, "CAPECITABINE": 15.316460427428714, "FASLODEX": 19.843535959797293, "IRESSA": 70.33819700889768, "KEYTRUDA": 17.719233578948494, "NEXAVAR": 6.543280564162787, "OPDIVO": 11.343486180993914, "TAGRISSO": 54.89363797859607, "null": 0.2069569285428611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7171.json
index 651b6bfc07a..f704094fad2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7171.json
@@ -1 +1 @@
-{"SYNAGIS": 2095.93597987918}
\ No newline at end of file
+{"ASPARAGINASE": 10.827097929273894, "COMIRNATY": 1.7391239573463684, "SHINGRIX": 4.843814823203149, "SPIKEVAX": 1.4709493386223853, "TOZINAMERAN": 0.5552076951455626, "VAXZEVRIA": 0.3719084039309752, "null": 0.7616381100774989}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7172.json
index 28dc96b2219..d85b29a0399 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7172.json
@@ -1 +1 @@
-{"ADCIRCA": 24.41211866780808, "ALEMTUZUMAB": 4.223329983070455, "APREPITANT": 11.862777383961882, "BUDESONIDE": 5.057234879258614, "BUSULFAN": 3.96868516111113, "CELLCEPT": 1.182006980432991, "CICLOSPORIN": 2.3798985565231137, "CYTARABINE": 2.9732110193388244, "DEXAMETHASONE": 1.230894731787061, "HIZENTRA": 4.202987451343903, "HUMIRA": 3.1163406970770247, "METFORMIN": 11.58714688475367, "OPSUMIT": 3.478501779432178, "ORKAMBI": 10.525695005938278, "ROTATEQ": 5.095594102355359, "SPINRAZA": 45.103951379338014, "SYNAGIS": 2194.961432432083, "TADALAFIL": 47.11616481082915, "TRACLEER": 2.4661660381695563}
\ No newline at end of file
+{"COMIRNATY": 0.7427713870357366, "PEGINTRON": 15.5253665329719, "SPIKEVAX": 0.6938995908893932, "null": 0.4361411527970011}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7173.json
index d28fbc8cfbd..28648dd2805 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7173.json
@@ -1 +1 @@
-{"SPIKEVAX": 7.866421370963003}
\ No newline at end of file
+{"AIMOVIG": 46.118680186205445, "null": 1.0416688758169317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7174.json
index 4500a9bfb37..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7174.json
@@ -1 +1 @@
-{"APIXABAN": 16.319361075265178, "SYNAGIS": 4984.922324601891}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7175.json
index c3c32cfbbd4..2a498adac12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7175.json
@@ -1 +1 @@
-{"null": 5.1014313881746425}
\ No newline at end of file
+{"CELLCEPT": 65.78333455836828, "CICLOSPORIN": 23.725693993406583, "null": 0.3438423733648594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7176.json
index df8c39de691..c4771991741 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7176.json
@@ -1 +1 @@
-{"ABATACEPT": 2.875009572772489, "ARAVA": 6.739448029026648, "CELLCEPT": 3.065839417299037, "CICLOSPORIN": 1.1739669761904463, "CIMZIA": 1.5001843129160863, "COSENTYX": 3.045733925402601, "ELIQUIS": 1.2696041145774335, "ENBREL": 1.3552489567616317, "FASENRA": 2.9221683638015103, "HIZENTRA": 2.99776304786257, "HUMIRA": 2.681413897117869, "IBRANCE": 1.3589392504215778, "INCRUSE": 12.982931428156302, "JANUVIA": 1.4136263593079543, "MEPOLIZUMAB": 14.855088238881269, "METHOTREXATE": 2.605522694602895, "NUCALA": 2.7244459686056373, "OMALIZUMAB": 20.169682576198927, "OPSUMIT": 4.499268914058862, "PEGASYS": 2.5453298115621683, "REVATIO": 5.1630924645837615, "SPRYCEL": 3.683894496107481, "SYNAGIS": 20.37157531997831, "TRELEGY": 4.065865544537248, "XELJANZ": 3.1055729765434616, "XOLAIR": 11.02649695039315}
\ No newline at end of file
+{"ARIPIPRAZOLE": 146.98008836534234, "AUBAGIO": 11.739164299153028, "AZATHIOPRINE": 49.82580816031388, "COMIRNATY": 0.1038465874602663, "LEMTRADA": 158.72825340749168, "null": 0.1951784211350745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7177.json
index 931887b861e..beedea351bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7177.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 28.571753214530126, "ENOXAPARIN": 26.958344887025344, "PLAVIX": 11.714670556254262, "TICAGRELOR": 38.35344174403821}
\ No newline at end of file
+{"AFINITOR": 4.704256447732936, "ALEMTUZUMAB": 26.75847960595123, "ALIMTA": 2.50187372835504, "APIDRA": 1.5727026345359685, "ARAVA": 0.1806668651400167, "ARIPIPRAZOLE": 17.931408777036363, "AUBAGIO": 9.06893602700145, "AZACITIDINE": 4.51923658288471, "AZATHIOPRINE": 1.9943664965785188, "BETAFERON": 6.762588910126118, "BEVACIZUMAB": 5.262818527850032, "BLINCYTO": 48.75910590826577, "CARIPRAZINE": 45.00167105885801, "CICLOSPORIN": 2.545473590190506, "CLADRIBINE": 29.096443801251997, "CLOPIDOGREL": 1.1032880856484597, "COMIRNATY": 0.1624553878820887, "COSENTYX": 1.063963467328913, "CYTARABINE": 4.575501663910246, "DARZALEX": 3.8959742743840735, "DEXAMETHASONE": 1.397893924554802, "DOCETAXEL": 4.09413321701253, "DOXORUBICIN": 7.865678461439518, "ENTRESTO": 2.484464169302409, "EXJADE": 1.9519658258322223, "FAMPYRA": 8.254085991891813, "GAZYVARO": 11.794093682792798, "GILENYA": 42.09043696906324, "IBRANCE": 2.5719526298019595, "ICLUSIG": 2.385453769951053, "JAKAVI": 4.879353823303812, "KESIMPTA": 29.657195624357826, "KEYTRUDA": 1.0140249966580264, "KISQALI": 4.53511348170126, "KYMRIAH": 22.333219464869316, "KYPROLIS": 4.577901740844326, "LEFLUNOMIDE": 3.418120765434603, "LEMTRADA": 33.562836826355564, "LEVOFLOXACIN": 0.6557047545458997, "MAVENCLAD": 327.4438447005385, "MEKINIST": 3.592330114879607, "METFORMIN": 19.43411798016228, "METHOTREXATE": 3.6644671561008, "OBINUTUZUMAB": 21.73966608870621, "OCRELIZUMAB": 2.554693708509088, "OLANZAPINE": 4.587552017378011, "PEGASYS": 1.26326611729336, "PEGINTERFERON": 1.2617733165222176, "PEGINTRON": 1.643124807179894, "PLAVIX": 0.3833819627135842, "PLEGRIDY": 8.919910410133243, "RINVOQ": 2.313012442958937, "RITUXIMAB": 6.772353738862478, "ROACTEMRA": 1.213614027478267, "SOLIRIS": 1.264137550504782, "SPIKEVAX": 0.0397279368809357, "STELARA": 0.5001774292349082, "SUTENT": 0.2764401031129337, "TEMODAL": 23.094458699195787, "TOPOTECAN": 8.37237025275072, "TOZINAMERAN": 0.3040120651370331, "VAXZEVRIA": 0.0297712894387061, "VENETOCLAX": 5.189973608480049, "VFEND": 1.3326696910993947, "XELJANZ": 2.1315597114809477, "ZOSTAVAX": 0.5632187890497523, "ZYPREXA": 0.6522194148744417, "null": 0.5731631760659534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7178.json
index 8121cb0496f..33f33367d77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7178.json
@@ -1 +1 @@
-{"ARZERRA": 14.017825957177514, "AUBAGIO": 1.4163671414199517, "AVAMYS": 16.89078865799146, "AZACITIDINE": 2.3763094965132394, "AZTREONAM": 18.13877969437827, "BENLYSTA": 2.5195299821805874, "BORTEZOMIB": 3.701934198328236, "BUDESONIDE": 2.0575917018166408, "BUPRENORPHINE": 1.245882277929734, "CARFILZOMIB": 4.527596176327422, "CELLCEPT": 2.0348538575716737, "CICLOSPORIN": 1.84758161059565, "CIMZIA": 1.441019608049095, "COSENTYX": 3.143105094469613, "DARATUMUMAB": 9.363441124372097, "DARZALEX": 2.1134895642540177, "DEXAMETHASONE": 1.7105567627642724, "DULOXETINE": 1.7898066248670674, "ENBREL": 1.9721711805826705, "ENTRESTO": 1.174287758212515, "ESBRIET": 3.218197350828289, "FASENRA": 1.910521980479714, "FLUTICASONE": 11.9293819834894, "FORSTEO": 1.218157277157652, "FULVESTRANT": 1.3309801337311828, "GAZYVARO": 10.827224774667783, "HIZENTRA": 21.701726261615917, "HUMAN": 2.5052957476922595, "HYQVIA": 10.082867576944707, "INCIVO": 2.2636438948909268, "INCRUSE": 9.707100258518134, "INFANRIX": 2.5450952612485733, "JAKAVI": 4.0705877568871625, "KESIMPTA": 3.871728013760523, "KYPROLIS": 6.063136943316445, "LACOSAMIDE": 1.649367325297178, "LEVOFLOXACIN": 1.123665273441992, "MABTHERA": 2.403266910951043, "MEPOLIZUMAB": 6.46393081707223, "METHOTREXATE": 5.383637697661907, "MMRVAXPRO": 2.498024128645964, "MYCOPHENOLATE": 1.6508529287581286, "NAGLAZYME": 6.334084435864783, "NPLATE": 1.736472379611234, "NUCALA": 6.246309394523245, "OFEV": 1.8610907113663289, "OMALIZUMAB": 21.58096657896734, "OPSUMIT": 1.8458421689967448, "ORKAMBI": 5.24819095864479, "PEGASYS": 1.0565463416899523, "PRIVIGEN": 2.1777443726492742, "RELVAR": 4.929279872948509, "REVATIO": 1.1388183166121664, "RINVOQ": 4.934694337120175, "RITUXIMAB": 2.8710002115688544, "ROACTEMRA": 3.2540977379548406, "ROTATEQ": 1.7783734577486614, "RUCONEST": 4.417830492592935, "SIMPONI": 4.77211241465386, "SOLIRIS": 4.528831017994116, "SPINRAZA": 31.54222771694424, "SPRYCEL": 1.140094332986625, "STELARA": 3.6742421960699816, "SYNAGIS": 15.948728751093402, "TRACLEER": 4.215746945787666, "TRELEGY": 2.37920405180024, "TREMFYA": 4.388729838912569, "VENCLYXTO": 4.994230510786925, "VFEND": 1.486129603512787, "XELJANZ": 5.279892682188207, "XOLAIR": 4.308261556089283}
\ No newline at end of file
+{"AFINITOR": 2.811429381483246, "ARAVA": 2.905013977835381, "ARIPIPRAZOLE": 9.737795438363294, "AUBAGIO": 3.8172761736016434, "CICLOSPORIN": 3.8816836998170743, "COMIRNATY": 0.3390068850898517, "CYTARABINE": 4.368453748466752, "ENBREL": 1.973884351044012, "GLIVEC": 30.45990786871446, "IBRANCE": 3.784636756964803, "JAKAVI": 5.883789310451248, "PEGASYS": 3.182507242259926, "RINVOQ": 4.935641035164708, "RUXOLITINIB": 24.70879291504317, "TOZINAMERAN": 0.7239968154799966, "VAXZEVRIA": 0.134858076100075, "VENCLYXTO": 29.55071079807676, "ZYPREXA": 1.8653014181280143, "null": 0.8830862105002035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7179.json
index 27d11cc1adc..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7179.json
@@ -1 +1 @@
-{"BUSULFAN": 41.77716462776085, "OMALIZUMAB": 27.6704034917253}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/718.json
index ba2556b2c37..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/718.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/718.json
@@ -1 +1 @@
-{"TEMOZOLOMIDE": 857.1310857801292}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7180.json
index 491fe0ccb28..76dc2b7044c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7180.json
@@ -1 +1 @@
-{"ARAVA": 2.4298096508246583, "CICLOSPORIN": 2.6926854621741496, "OPSUMIT": 5.847635285556516, "SIMPONI": 4.627088503696209, "SOLIRIS": 6.825116666609919, "SPINRAZA": 47.9386322924686, "SYNAGIS": 28.712924966134054, "TRACLEER": 8.63540280505277}
\ No newline at end of file
+{"CICLOSPORIN": 8.491603001469379, "COMIRNATY": 0.2021311100796949, "LEVOFLOXACIN": 6.706158065594662, "null": 2.550998337714109}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7181.json
index 3e652c9995c..8bf42a2c08f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7181.json
@@ -1 +1 @@
-{"AVAMYS": 27.946816646585976, "NUCALA": 17.555974229529102, "null": 1.02195079631307}
\ No newline at end of file
+{"ALEMTUZUMAB": 48.00179187088992, "COMIRNATY": 0.1519644476099975, "ENTRESTO": 6.499894652432314, "LEMTRADA": 99.31376832212716, "OMALIZUMAB": 10.778290163816123, "SPIKEVAX": 0.4830890667625055, "ZOSTAVAX": 4.5545719486368, "null": 0.4731584538948241}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7182.json
index 39c1d23162c..f95afb24572 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7182.json
@@ -1 +1 @@
-{"QUTENZA": 112.0339539867263, "TOZINAMERAN": 1.0784349693795, "null": 2.0044879529295985}
\ No newline at end of file
+{"IBRANCE": 12.375154195752822, "null": 0.7749757052326606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7183.json
index 3c54647a8db..c6c7b3c1a51 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7183.json
@@ -1 +1 @@
-{"DULOXETINE": 179.58971186388027, "null": 1.7241948535250735}
\ No newline at end of file
+{"null": 3.091661048238552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7184.json
index 5eb24884319..bfcbe7b338e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7184.json
@@ -1 +1 @@
-{"RUCONEST": 268.59597081081745, "TOZINAMERAN": 1.6161644250311198, "null": 1.3770844468354049}
\ No newline at end of file
+{"MICARDIS": 28.219296444610364, "null": 5.664987656771083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7185.json
index 7ae26a3475d..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7185.json
@@ -1 +1 @@
-{"SPINRAZA": 1034.927608000197}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7186.json
index d523c9b6810..48879fdde7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7186.json
@@ -1 +1 @@
-{"COMIRNATY": 2.1053360165839483, "COVID19": 1.385560308963912, "SPIKEVAX": 3.204546507841324, "VAXZEVRIA": 3.5041590465242423}
\ No newline at end of file
+{"IPILIMUMAB": 558.4777228864215, "KEYTRUDA": 15.217136936711006, "OPDIVO": 110.31049889217404, "PEMBROLIZUMAB": 41.168308194680186, "YERVOY": 83.95034300033848}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7187.json
index 1a196cb87a9..2376b8893ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7187.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 14.277963504671536, "ENTACAPONE": 234.97208418261712, "OLANZAPINE": 34.27230214968965, "null": 2.0305199353929235}
\ No newline at end of file
+{"CICATRIZANTS": 2494.937340658309, "CICLOSPORIN": 11.012621795219571, "COMIRNATY": 0.152206447993107, "null": 1.913533161407878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7188.json
index fb18f676f59..ed776610edf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7188.json
@@ -1 +1 @@
-{"COVID19": 1.921223333273213, "null": 1.2243952870523205}
\ No newline at end of file
+{"null": 0.8839953717733847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7189.json
index 9e473f0088b..f4433c22d6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7189.json
@@ -1 +1 @@
-{"ABILIFY": 2.9236414487355464, "AIMOVIG": 1.9348765619195123, "ARIPIPRAZOLE": 2.884664987085026, "AUBAGIO": 1.0422892565465642, "BRINTELLIX": 7.291873065479611, "BYDUREON": 1.7760122293374203, "CARBIDOPA": 6.680430600806018, "CIRCADIN": 10.03443665016759, "COVID19": 1.2898764150895576, "CYMBALTA": 3.075314982114855, "ENBREL": 2.0043714520713967, "ENZALUTAMIDE": 4.474860887646192, "FAMPYRA": 3.876156547255435, "FIRDAPSE": 2.5400433727668816, "FORSTEO": 1.665473051659692, "LATUDA": 5.713083208448298, "LYRICA": 1.688870437648399, "MELATONIN": 2.562129463651672, "MIRABEGRON": 13.378735557660166, "NEUPRO": 44.914537122909735, "OLANZAPINE": 2.7539236015705137, "OXYBUTYNIN": 5.103425248562036, "PANTOPRAZOLE": 1.14846327489366, "SIFROL": 28.826429076411973, "SUBOXONE": 2.4327105004168503, "SYCREST": 12.21988547548867, "XTANDI": 5.586587972308941, "XYREM": 4.735675121532666, "ZOSTAVAX": 4.2083433065172, "ZYPADHERA": 5.691738086625223, "ZYPREXA": 2.030360964883424, "null": 1.7592188108251674}
\ No newline at end of file
+{"ARAVA": 0.402878411385719, "COMIRNATY": 0.2219652921429651, "JAKAVI": 6.906210802647011, "RITUXIMAB": 4.589913685975032, "ROACTEMRA": 4.452919435258999, "SIMPONI": 3.187009380286599, "SPRYCEL": 10.320595242868482, "STELARA": 2.0812230624614148, "TOZINAMERAN": 0.3047091780038319, "VAXZEVRIA": 0.1048892024304665, "null": 1.5413605052821835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/719.json
index 727bdd2f2fe..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/719.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/719.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 81.06149364194692, "TEMOZOLOMIDE": 470.633906066964}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7190.json
index d51b1c579f9..5c1122093b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7190.json
@@ -1 +1 @@
-{"ABILIFY": 4.191271032900143, "AERIUS": 2.034319388879596, "AIMOVIG": 1.5291658188812385, "ARIPIPRAZOLE": 3.141733570570855, "AXURA": 15.079259359001355, "AZILECT": 6.917620583942053, "BENZODIAZEPINE": 1.7069638625205363, "BEXSERO": 2.401166784073336, "BRINTELLIX": 4.904336087628148, "BRIVIACT": 1.9688953862803464, "BUPRENORPHINE": 1.6304214932929055, "CANNABIDIOL": 3.7255688331177415, "CHAMPIX": 3.5073719734347177, "CIRCADIN": 8.214943239839949, "COMTAN": 2.4299178327843176, "CYMBALTA": 2.3646762507507044, "DEXMEDETOMIDINE": 2.887949145125689, "DULOXETINE": 1.107595126390937, "ENTACAPONE": 2.3832442306222785, "EXELON": 3.482875786032762, "FAMPYRA": 1.1784262492064566, "FENTANYL": 1.3816478422960925, "FYCOMPA": 5.022740264063131, "HEXACIMA": 15.067242250313717, "HEXYON": 14.785980249796228, "HYDROCHLOROTHIAZIDE": 2.075349399758765, "HYDROCORTISONE": 1.2630010470758035, "INFANRIX": 12.655303947558858, "INVEGA": 2.839941153735127, "IRON": 2.4686466235699998, "KAFTRIO": 2.037527893989658, "KEPPRA": 1.9072944138522632, "KETOCONAZOLE": 4.638903363901665, "KIOVIG": 1.2658167235476687, "LATUDA": 8.107758523362023, "LEVETIRACETAM": 1.438179305667433, "LEVODOPA": 3.786902530408209, "LEVOFLOXACIN": 1.2247705636502824, "LYRICA": 1.9710347556187624, "MELATONIN": 1.6450260787979805, "MIDAZOLAM": 2.086160344776439, "MIRCERA": 1.5455640728183837, "MMRVAXPRO": 4.237835274856017, "NIMENRIX": 2.135103420685388, "OLANZAPINE": 3.2272650263223235, "PREVENAR": 8.435183808845776, "PROPRANOLOL": 2.4401839366910543, "REAGILA": 22.962270011497527, "RISPERIDONE": 2.8224608212948032, "ROTATEQ": 6.300689708218667, "SIFROL": 3.6987992323590873, "STALEVO": 1.1198020434641676, "SUBOXONE": 2.5986642384327245, "SYCREST": 6.105980804142208, "TAMIFLU": 3.1186924182615128, "TELMISARTAN": 1.130800217051328, "VALDOXAN": 15.997917929639424, "VFEND": 3.5786289372958136, "VIMPAT": 1.882082674274609, "VORICONAZOLE": 2.121572359881645, "XEPLION": 8.8291692842702, "ZYPADHERA": 13.442609828665727, "ZYPREXA": 3.2539282386160946, "null": 2.3688837251653148}
\ No newline at end of file
+{"KALETRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7191.json
index b596484192b..c67a1b61aa4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7191.json
@@ -1 +1 @@
-{"null": 1.295545584518763}
\ No newline at end of file
+{"ABACAVIR": 2.0673110052091954, "AFINITOR": 3.349610165735503, "ALIMTA": 2.48076188490676, "ARAVA": 0.7702148050104787, "BYDUREON": 1.3025407867568812, "CELECOXIB": 14.568999832387243, "CIALIS": 8.494286139900328, "CLOPIDOGREL": 14.235607073042049, "COMIRNATY": 1.44500239604217, "CYMBALTA": 0.8775841093808461, "ELIQUIS": 1.1982758978405232, "ESOMEPRAZOLE": 4.770117625973984, "FASLODEX": 9.579064640082343, "FULVESTRANT": 7.55837048742187, "GARDASIL": 0.4291352393357559, "HERCEPTIN": 7.097262975626716, "HUMALOG": 1.1464511206739112, "IBRANCE": 8.078693398261807, "IMBRUVICA": 10.451546308310611, "IRBESARTAN": 4.704948622008581, "JARDIANCE": 0.8247647072544191, "KEYTRUDA": 0.8025955501295707, "LANTUS": 0.6106170349009202, "MEKINIST": 3.577902232297576, "OCEAN": 171.59470648540855, "OPTIMARK": 1.7347687974555337, "PLAVIX": 0.8217452777887567, "RAPAMUNE": 15.362788811535568, "SPIKEVAX": 0.7017141905282229, "STELARA": 1.000835054213167, "SUTENT": 0.8998038771905329, "TOZINAMERAN": 1.5941056659075106, "VAXZEVRIA": 0.430855189534273, "XELJANZ": 0.4364767376818266, "ZOSTAVAX": 0.9526936878574226, "null": 0.4808700240821897}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7192.json
index f846912b42f..c079965f928 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7192.json
@@ -1 +1 @@
-{"AVAMYS": 20.30760107716089, "NUCALA": 14.675793833963285, "OMALIZUMAB": 12.29904324609998}
\ No newline at end of file
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7193.json
index c2fa578f32a..d20849aeb4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7193.json
@@ -1 +1 @@
-{"BRIDION": 17.914354974929932, "FENTANYL": 3.0561816175850622, "INFANRIX": 21.22073000274764, "KEPPRA": 3.7383480096237856, "MIDAZOLAM": 10.407503097962907, "TRACLEER": 9.112999858904097, "null": 1.4740381781219258}
\ No newline at end of file
+{"null": 1.6087217243554337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7194.json
index 2245313136a..b0dc27cdf88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7194.json
@@ -1 +1 @@
-{"null": 2.27748077074544}
\ No newline at end of file
+{"ASPARAGINASE": 3440.467664101077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7195.json
index 8b5bb8b5373..9314c95d8ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7195.json
@@ -1 +1 @@
-{"STELARA": 8.556838414656077, "null": 15.331727054203268}
\ No newline at end of file
+{"ARANESP": 0.9948096208908546, "ARAVA": 0.435258151397467, "ASPARAGINASE": 2.085845204885646, "AZATHIOPRINE": 1.8482672732291032, "BARACLUDE": 5.541480638555672, "BENLYSTA": 2.2037318005382605, "BIKTARVY": 3.6713867640859537, "BYETTA": 1.271018484382453, "CANCIDAS": 5.136868806508928, "CARMUSTINE": 18.73150043133445, "CELLCEPT": 9.147717001955543, "CICLOSPORIN": 4.763208771913404, "CIMZIA": 1.6147593322327511, "COMIRNATY": 0.22059175753079, "COSENTYX": 1.5428907597196808, "CYTARABINE": 5.557509956389152, "DESCOVY": 9.143998226139692, "DEXAMETHASONE": 1.8950606170279125, "DOXORUBICIN": 2.988285940887218, "ELIQUIS": 1.0756467012173183, "ENBREL": 3.493247850193469, "ENTYVIO": 1.579297550893105, "EPIVIR": 3.4342327172845644, "ESOMEPRAZOLE": 3.872887182904488, "EVENITY": 2.698702429827353, "EVISTA": 2.3251834448219832, "EXJADE": 1.1930169984245906, "FASLODEX": 1.013915121696789, "FORSTEO": 1.124587447221567, "GARDASIL": 0.4415670704097377, "HARVONI": 2.370026319083788, "HERCEPTIN": 2.0960493033904832, "HIZENTRA": 2.254165514258733, "HUMALOG": 0.8981579965487726, "HUMIRA": 2.067074338876408, "IBRANCE": 0.4835250295369735, "ISENTRESS": 5.136817447630272, "JAKAVI": 3.2879441256676487, "JANUMET": 2.3013512863584364, "JANUVIA": 0.7812238671480868, "JARDIANCE": 0.3918461184635267, "KALETRA": 2.79910283488415, "KEYTRUDA": 0.5350660041143694, "KYMRIAH": 7.175316025947196, "LANTUS": 1.2251362381587876, "MABTHERA": 4.692779402081943, "METHOTREXATE": 6.167121540085994, "NEULASTA": 5.950220864120438, "NORVIR": 7.656605140753281, "NPLATE": 11.45106539331197, "NUCALA": 0.6281668986019165, "OLANZAPINE": 1.7259543422592407, "PEGASYS": 0.8961840680793284, "PEGINTERFERON": 1.3242615268411746, "PEGINTRON": 3.008843057415183, "RAPAMUNE": 7.331350318131109, "REMICADE": 6.610938415455175, "RINVOQ": 5.703873718687124, "RITUXIMAB": 4.671316202631428, "SHINGRIX": 0.5925212069006603, "SIMPONI": 4.330612911805459, "SKYRIZI": 9.180553763851163, "SOLIRIS": 0.860163351079342, "SOVALDI": 6.231909913666382, "SPIKEVAX": 0.1626544954921069, "SPRYCEL": 1.9588036949733096, "STELARA": 4.126444279094769, "SUTENT": 0.1661045800415899, "TASIGNA": 0.9683691267090108, "TIVICAY": 10.450593910608385, "TOZINAMERAN": 0.6560924577827012, "TRELEGY": 1.82729235303089, "TRUVADA": 0.2468507691288232, "VAXZEVRIA": 0.0878651713306469, "VFEND": 1.7779605399996288, "VIAGRA": 1.1329084893991577, "XELJANZ": 4.034165207170942, "XOLAIR": 3.184390382058309, "YESCARTA": 12.77224862846974, "ZOSTAVAX": 1.6128784284410378, "ZYPREXA": 0.5501508558173902, "null": 0.8686983056990166}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7196.json
index 6d692ae394c..c21fd02e79a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7196.json
@@ -1 +1 @@
-{"ADEMPAS": 2.6671319913359435, "BRINTELLIX": 2.37121056785923, "BYETTA": 1.0927545587639726, "CHAMPIX": 2.1300898234943406, "CLOPIDOGREL": 1.223644008654588, "ESBRIET": 1.242230246574752, "FORSTEO": 1.5167313658010793, "GONALF": 6.385225455519896, "IBRANCE": 1.3353120483981775, "IBUPROFEN": 3.0653927796386777, "IRINOTECAN": 1.433027809070353, "JANUMET": 1.4879270934037765, "NIMENRIX": 1.174361549707677, "OFEV": 1.0348987187175105, "OPSUMIT": 1.0237914067015763, "PEGASYS": 1.2205288854692526, "PEGINTRON": 1.0039086556127643, "PRIVIGEN": 1.0823402662792505, "ROTATEQ": 2.35156960741533, "SUTENT": 2.907338384071568, "TAMIFLU": 1.326101256890914, "TRELEGY": 2.398514662604955, "TRULICITY": 2.473882452579214, "VICTOZA": 2.2573875374910592, "VIMPAT": 1.1252202810631002, "VOTRIENT": 1.7765678829408376, "XELODA": 2.153909571237612, "XTANDI": 1.406297639558207, "null": 1.893602416735258}
\ No newline at end of file
+{"ATEZOLIZUMAB": 1595.2712923362303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7197.json
index a51df7c472a..28d124e83bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7197.json
@@ -1 +1 @@
-{"ARANESP": 193.21643531882725}
\ No newline at end of file
+{"COMIRNATY": 0.8543162640245086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7198.json
index 6be3db21959..08d12b96b72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7198.json
@@ -1 +1 @@
-{"ARANESP": 111.98983190628913, "CICLOSPORIN": 5.89687573917482, "MIRCERA": 169.81047159311254, "PEGASYS": 3.308455097905944}
\ No newline at end of file
+{"ADALIMUMAB": 0.0870570598281311, "ALEMTUZUMAB": 22.882486309700685, "AMIKACIN": 3.1734161064888395, "ARAVA": 0.2300878858106322, "ASPARAGINASE": 10.253602836845584, "AUBAGIO": 12.870535835286068, "AVASTIN": 1.4501397532047575, "AZATHIOPRINE": 4.6404939428073, "BASILIXIMAB": 6.699503461802639, "BENLYSTA": 2.593712939407104, "BETAFERON": 3.0272881448863496, "BEVACIZUMAB": 1.7555674698748485, "BORTEZOMIB": 6.087349356498266, "BUSULFAN": 2.970720101187069, "CARFILZOMIB": 6.261356570111651, "CARMUSTINE": 7.681563915256989, "CELLCEPT": 5.8890376314022514, "CICLOSPORIN": 2.706917050375426, "CLADRIBINE": 68.60171828001596, "CLOFARABINE": 23.736809040512, "COMIRNATY": 0.2037582448090133, "COSENTYX": 0.3739796710730349, "COTELLIC": 3.783710496363629, "CYTARABINE": 2.077239725416044, "DARZALEX": 11.564370618507894, "DEXAMETHASONE": 7.659432708270032, "DOCETAXEL": 2.916998146469159, "DOXORUBICIN": 4.208275759679525, "EFAVIRENZ": 3.9351336551695297, "FAMPYRA": 8.918996018105638, "FASENRA": 1.1462436236756883, "FUZEON": 42.21135955493028, "GANCICLOVIR": 3.5224167646458038, "GAZYVARO": 10.1813265001177, "HALAVEN": 4.667670654744531, "IBRANCE": 0.3891932266620364, "INCIVO": 2.871220037072409, "IRBESARTAN": 9.354812321814732, "IRINOTECAN": 2.220622961922506, "JAKAVI": 3.1364570351249177, "KALETRA": 2.693883248128295, "KEPPRA": 1.0404795013853807, "KESIMPTA": 9.54347259262302, "KEYTRUDA": 0.6234388965814774, "KYMRIAH": 2.6902697229658705, "LEMTRADA": 28.234542375342723, "LEVETIRACETAM": 1.445608065313627, "LEVOFLOXACIN": 0.5473566054525797, "LUTATHERA": 30.395794333192743, "MABCAMPATH": 28.46581378946015, "MABTHERA": 8.472184485878547, "MAVENCLAD": 244.83948294025197, "MERCAPTOPURINE": 6.784266608939834, "METHOTREXATE": 5.686541626353795, "MYCOPHENOLATE": 4.9875458444564815, "NEXAVAR": 0.895047397172354, "OLANZAPINE": 0.6737314532004517, "OLAPARIB": 14.286898213966388, "OLYSIO": 4.572777251010968, "PANTOPRAZOLE": 2.175307964882341, "PEGASYS": 1.0647979129969094, "PEGINTERFERON": 3.106132958839261, "PEMBROLIZUMAB": 1.4983915637940208, "PLEGRIDY": 11.68766181261934, "POTELIGEO": 62.31663035119141, "PRIVIGEN": 1.3080776995742502, "RIBAVIRIN": 3.032454403605515, "RINVOQ": 3.700926823491523, "RITUXIMAB": 5.873828237726312, "ROACTEMRA": 3.87687009293732, "RUXOLITINIB": 4.17910572908198, "SPIKEVAX": 0.0965728375019571, "STELARA": 1.197689523306808, "STIVARGA": 1.6492357386854457, "SUTENT": 0.775768019672356, "TEMODAL": 16.674801654465757, "TEMOZOLOMIDE": 66.75238665159297, "TISAGENLECLEUCEL": 75.03930993327171, "TOZINAMERAN": 0.0744527946257713, "TREMFYA": 2.043584170517762, "TRUVADA": 0.1808566626318994, "VAXZEVRIA": 0.094329062705632, "XELJANZ": 1.2106674763679146, "XOLAIR": 0.5307519135581228, "ZELBORAF": 2.933488122200715, "ZERBAXA": 343.82570308638475, "ZYPREXA": 1.332036741665106, "null": 0.7272506065718902}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7199.json
index 0412577bb4d..63a755acd72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7199.json
@@ -1 +1 @@
-{"CICLOSPORIN": 11.142792737758612, "EXJADE": 23.22915423843535, "JAKAVI": 14.129701593787344, "PRIVIGEN": 31.6345372472868, "SOLIRIS": 112.93651513627036}
\ No newline at end of file
+{"RITUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/72.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/72.json
index 40b06fc792f..381277d4d82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/72.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/72.json
@@ -1 +1 @@
-{"null": 1.410174837693863}
\ No newline at end of file
+{"MISOPROSTOL": 376.5301586356688, "null": 65.1180162168045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/720.json
index b462e7b3f06..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/720.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/720.json
@@ -1 +1 @@
-{"ABILIFY": 1.2966499330455834, "ACLIDINIUM": 17.626057577583772, "AMIKACIN": 2.071857426826283, "ARIPIPRAZOLE": 1.854616499924648, "ASPARAGINASE": 1.2264030167515871, "ATAZANAVIR": 3.932043254125021, "AUBAGIO": 1.3697854004916508, "AZILECT": 7.537200585877913, "BENZODIAZEPINES": 19.931863640616825, "BETAFERON": 3.682963182425097, "BRIVIACT": 2.857977774886954, "BUPIVACAINE": 1.9684536635908036, "CAPECITABINE": 1.445802834710718, "CICLOSPORIN": 1.2227825354546178, "DEXAMETHASONE": 1.0125521601806966, "EBIXA": 5.481837706584559, "EMTRICITABINE": 2.82274568064511, "FAMPYRA": 2.7133848378113123, "FYCOMPA": 14.899451907782906, "GARDASIL": 2.372710911892667, "HALAVEN": 2.2111469409884283, "KEPPRA": 5.81927392658869, "LACOSAMIDE": 8.123048307583291, "LEMTRADA": 2.821490732818384, "LEVETIRACETAM": 12.452946068832151, "LYRICA": 3.2096131492473, "MELATONIN": 4.14605254841787, "MICARDIS": 1.354679771266026, "MMRVAXPRO": 2.0973131117675377, "NIMENRIX": 1.7657413653299951, "NOVORAPID": 1.5466163225188398, "OLANZAPINE": 2.7552988641642573, "PANTOPRAZOLE": 5.778703416993072, "PEGINTRON": 1.6083635575216657, "PREGABALIN": 1.5252926295384923, "RISPERIDONE": 5.013150284737163, "VIMPAT": 6.340599246525355, "ZYPADHERA": 22.57490787699817, "ZYPREXA": 2.008740988940944, "null": 2.9230026521847443}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7200.json
index 9b179373d9e..aa744d9de15 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7200.json
@@ -1 +1 @@
-{"ARANESP": 66.72117700180749}
\ No newline at end of file
+{"ALEMTUZUMAB": 70.84075901806199, "ANAKINRA": 9.721142198640267, "AZATHIOPRINE": 19.25730463746662, "BUSULFAN": 17.7821947715555, "CELLCEPT": 25.32954794036056, "CICLOSPORIN": 34.24714111640912, "CIMZIA": 3.467813663719439, "GOLIMUMAB": 171.54023905889187, "METHOTREXATE": 36.9951177851043, "RITUXIMAB": 6.16630108447986, "SIMPONI": 5.892250758677986, "XELJANZ": 1.98762034922627, "null": 0.4002979299526572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7201.json
index 0ca206a47c0..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7201.json
@@ -1 +1 @@
-{"SOLIRIS": 45.13466966658407, "null": 1.3963864255749423}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7202.json
index 580cd49ef0a..f6cc4db0a54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7202.json
@@ -1 +1 @@
-{"AVASTIN": 3.3459176383378346, "BEOVU": 226.58917402096003, "BROLUCIZUMAB": 189.09444054438305, "EVISTA": 7.225426963925329, "EYLEA": 93.34376209234352, "ICLUSIG": 7.683465024856064, "PEGASYS": 1.9812567329697452, "PEGINTRON": 5.978729605743709, "RINVOQ": 3.309424599762452, "VIAGRA": 10.442709032943352, "ZOSTAVAX": 1.1290678620594028}
\ No newline at end of file
+{"SPRYCEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7203.json
index 1ffebc51a08..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7203.json
@@ -1 +1 @@
-{"null": 1.359417735449565}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7204.json
index d8c482442e3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7204.json
@@ -1 +1 @@
-{"PEGASYS": 4.077166531413983, "PEGINTRON": 16.190850188273497, "VAXZEVRIA": 1.7114646270589982, "VIAGRA": 19.101362640800307}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7205.json
index 2eaa598f27b..1ee9ed9b9b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7205.json
@@ -1 +1 @@
-{"null": 1.53567740245871}
\ No newline at end of file
+{"null": 1.8743496000676312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7206.json
index 85fde97302d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7206.json
@@ -1 +1 @@
-{"BEOVU": 96.41387334931284, "EYLEA": 65.44171815933119, "GANCICLOVIR": 36.80243120887074, "LUXTURNA": 8002.012273288915, "MELPHALAN": 124.06161256418096, "VIAGRA": 15.485430529342086, "ZOSTAVAX": 11.905398788255424}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7207.json
index efff87c8e62..30745cd3ebe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7207.json
@@ -1 +1 @@
-{"CICLOSPORIN": 19.471767814740115}
\ No newline at end of file
+{"null": 2.5644314902540217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7208.json
index 4d44c595ea4..1d366123e34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7208.json
@@ -1 +1 @@
-{"LUXTURNA": 9965.152892245856, "null": 1.2512093287123718}
\ No newline at end of file
+{"ARAVA": 1.9069666363790445, "COMBIVIR": 26.695846554904747, "EPIVIR": 33.722367037941495, "IBRANCE": 7.539467870926835, "LAMIVUDINE": 30.990901072345288, "MEPOLIZUMAB": 10.828752650413414, "PEGASYS": 3.1822239735592426, "null": 1.0639744518392358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7209.json
index 313e3dbc9fe..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7209.json
@@ -1 +1 @@
-{"APIDRA": 2.7577817439844647, "AVASTIN": 1.7648487934679298, "AZATHIOPRINE": 2.3893031371314213, "BRAFTOVI": 23.58744299445615, "BYDUREON": 2.7174814349954635, "BYETTA": 1.6429172542761514, "COBIMETINIB": 19.79946613171682, "COTELLIC": 15.115697027713354, "CYMBALTA": 1.1847784318325705, "EXFORGE": 1.7177033263350323, "EYLEA": 26.495385864554127, "GANCICLOVIR": 15.433064259091855, "HUMALOG": 8.587443620426185, "INSULIN": 2.797034573153604, "JETREA": 309.59997281586044, "LANTUS": 6.718202425451579, "LUXTURNA": 305.5062079943043, "MEKINIST": 13.613952438710836, "OMALIZUMAB": 1.2573243574323585, "PEGASYS": 4.440742394406674, "PEGINTRON": 3.3842548095876235, "RINVOQ": 2.407278713548162, "STIVARGA": 1.1735360059619004, "TAMIFLU": 1.2923625627101658, "TASIGNA": 1.2516289640639795, "TRULICITY": 2.1693043300112214, "VIAGRA": 6.72645592197961, "VOTRIENT": 4.794891790434898, "ZOSTAVAX": 2.503996107269665}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/721.json
index f5a6a7d49b4..f740c42fd0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/721.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/721.json
@@ -1 +1 @@
-{"ADCIRCA": 9.607014183201295, "AFINITOR": 4.082852631121483, "ALIMTA": 1.787832108541149, "APIXABAN": 2.880160341967985, "APREPITANT": 27.950465274634503, "BEVACIZUMAB": 1.9690761834135435, "BORTEZOMIB": 13.363535612506402, "BYDUREON": 4.164024426438449, "BYETTA": 8.327254198124502, "CICLOSPORIN": 1.16047441784983, "CYTARABINE": 5.2362575992736815, "DEXAMETHASONE": 5.011152585098555, "ESOMEPRAZOLE": 8.568907302197651, "EXJADE": 2.6752595943509974, "FENTANYL": 2.038881015674296, "FIRDAPSE": 3.7577919151614183, "IBUPROFEN": 5.642420036713486, "INTEGRILIN": 13.599422902071366, "IRESSA": 2.4266284598894226, "JANUMET": 14.223958260351814, "JANUVIA": 11.915110828589231, "KEYTRUDA": 2.748518175538805, "KYMRIAH": 4.00220821779747, "MEPOLIZUMAB": 2.044985143358633, "MIDAZOLAM": 4.135318789284506, "NAGLAZYME": 3.986047322358089, "NOT": 3.1221692277212894, "NPLATE": 4.484617580991387, "NUCALA": 7.488699292738349, "OLANZAPINE": 1.0809899454470917, "OPDIVO": 1.705343701122561, "OPTIMARK": 2.6281904096161006, "PANTOPRAZOLE": 8.742439929774813, "PEMBROLIZUMAB": 2.228559301944032, "RITUXIMAB": 1.3714694026651388, "SOLIRIS": 1.277711271784035, "SPINRAZA": 33.12181758665838, "SPRYCEL": 1.957275828484448, "SYNAGIS": 9.246859874464857, "TAGRISSO": 2.37771660757051, "TAMIFLU": 1.517002302594888, "TASIGNA": 2.1153497301608684, "THALIDOMIDE": 5.550066240676565, "TRELEGY": 1.300364542301976, "UMECLIDINIUM": 17.501067722383226, "VOTRIENT": 1.322655104392059, "ZOMETA": 23.739961690060543, "ZOSTAVAX": 2.3182320437588704, "ZYPREXA": 1.197143906773679}
\ No newline at end of file
+{"NOVOSEVEN": 4404.315166762161}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7210.json
index 15e4f067477..53d044ce873 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7210.json
@@ -1 +1 @@
-{"BEOVU": 26.523705641859674, "EYLEA": 15.356751614827449, "HUMALOG": 10.52188030825366, "LANTUS": 12.232723493107692, "PEGASYS": 3.690120327247411, "PEGINTRON": 4.0169389983323285, "VIAGRA": 5.300067416047055, "VIGABATRIN": 495.6011520809989, "ZOSTAVAX": 2.977021239613837, "null": 1.2177987439972129}
\ No newline at end of file
+{"ENZALUTAMIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7211.json
index 78fdd47df76..bf27a3f6add 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7211.json
@@ -1 +1 @@
-{"BEOVU": 293.47867579839766, "ZOSTAVAX": 23.582424866923528}
\ No newline at end of file
+{"COMIRNATY": 0.2733387615330219, "LACOSAMIDE": 51.73103555922069, "null": 2.713102860302661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7212.json
index 418ebe06766..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7212.json
@@ -1 +1 @@
-{"BEOVU": 101.652823916932, "EYLEA": 24.19964606286488, "INTRONA": 31.436448157819083, "PEGASYS": 36.38676998837902, "PEGINTERFERON": 64.12214875453809, "PEGINTRON": 94.25267125992168}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7213.json
index 0a4169a3391..b28cc5c4981 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7213.json
@@ -1 +1 @@
-{"ABACAVIR": 1.129114088644366, "APIDRA": 3.028669202061544, "AVANDIA": 1.2472562313021265, "AVASTIN": 2.7356853705294304, "BEOVU": 56.89751892785781, "BRILIQUE": 3.5064055797714837, "BROLUCIZUMAB": 50.36075305203824, "CICLOSPORIN": 1.617509242438942, "CLOPIDOGREL": 3.5420136011383647, "CYTARABINE": 1.551144111855305, "ELIQUIS": 4.072032575720949, "EVISTA": 9.044511759070131, "EYLEA": 76.53477427877937, "HUMALOG": 5.029611148245983, "INSULIN": 1.4709001662696968, "INTRONA": 33.485233373825295, "LANTUS": 6.276948999911585, "NEXAVAR": 1.1788640428145143, "NOVORAPID": 1.4705933377258948, "PEGASYS": 8.884964568376708, "PEGINTERFERON": 8.071470233191773, "PEGINTRON": 24.14369905346032, "PLAVIX": 8.532573482211335, "RIBAVIRIN": 1.6614280027412878, "SPRYCEL": 2.576803306524529, "TRULICITY": 1.730204429891185, "VFEND": 6.022153089526001, "VIAGRA": 8.816283129497826}
\ No newline at end of file
+{"null": 1.0697945780850726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7214.json
index bf7b71b8bc9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7214.json
@@ -1 +1 @@
-{"HUMALOG": 9.023996745198552, "JETREA": 1680.568291975413, "LANTUS": 6.299003078128232, "PEGASYS": 2.335385519740654}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7215.json
index c7c66bcb6ca..3d10e40cbce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7215.json
@@ -1 +1 @@
-{"BEOVU": 384.2242388195816, "EYLEA": 23.23073394851843, "PEGASYS": 3.854736152723765, "PEGINTERFERON": 87.61303857610712, "PEGINTRON": 22.977075856824367}
\ No newline at end of file
+{"null": 1.006633644640497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7216.json
index 2919cf80724..0a93f8bd6d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7216.json
@@ -1 +1 @@
-{"COVID19": 15.30924681327344, "TOZINAMERAN": 7.01482029435367}
\ No newline at end of file
+{"SUBOXONE": 28.74245677671753, "null": 1.769551911951455}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7217.json
index 6c1e9d3f61e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7217.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7217.json
@@ -1 +1 @@
-{"EYLEA": 130.09748721286016}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7218.json
index cc5cfb6372d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7218.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7218.json
@@ -1 +1 @@
-{"BEOVU": 3097.1492635585246, "BROLUCIZUMAB": 1008.7292465087723}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7219.json
index c5947c0bab2..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7219.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7219.json
@@ -1 +1 @@
-{"AVASTIN": 10.193139501189185, "BEOVU": 208.7182510189823, "BRAFTOVI": 40.14540824223618, "BROLUCIZUMAB": 250.10108620946292, "EYLEA": 120.55891837390185, "JETREA": 295.54086089338927, "LANTUS": 1.88422670968519}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/722.json
index a08c778b8e1..ac64ca349f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/722.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/722.json
@@ -1 +1 @@
-{"null": 3.8062365289207896}
\ No newline at end of file
+{"ADVATE": 1504.9310023749174, "null": 0.3714687163175711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7220.json
index 4cf5c05371b..901e99f0bb4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7220.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7220.json
@@ -1 +1 @@
-{"null": 1.2771863815457942}
\ No newline at end of file
+{"ACE": 25.88607086778382, "ACETIC": 2094.342912544314, "ADALIMUMAB": 19.968191539330903, "ALIGN": 103.1497414299534, "AMINOSALICYLIC": 52.69591190606454, "ANORO": 1.4809211868147725, "APIDRA": 2.005575093212148, "AVAMYS": 100.56898134947376, "BEOVU": 2.753031074251332, "BUDESONIDE": 56.72307316788549, "BYDUREON": 0.974886648934891, "BYETTA": 1.3673735926722022, "COMIRNATY": 0.0675718822339892, "CYMBALTA": 0.2055223037458719, "ELIQUIS": 2.6437288118409787, "ERTAPENEM": 23.45679727338528, "EVISTA": 1.4307085674898603, "EYLEA": 6.595572038170715, "FORSTEO": 0.4152197324324593, "HUMALOG": 6.8730101542488296, "HUMIRA": 1.482366958391206, "IBRANCE": 0.90398852303329, "INCRUSE": 4.22004828739168, "INSULIN": 1.4842250660387668, "JARDIANCE": 0.4395857322798167, "LANTUS": 7.949881851265563, "LEVEMIR": 4.951503391550416, "MEPOLIZUMAB": 0.6041605579716466, "OFEV": 0.8547631348815246, "OPSUMIT": 0.4049563503754699, "PEGINTRON": 0.2820227951650093, "PLAVIX": 1.1623762956209176, "REVATIO": 1.8561593924882127, "SPIKEVAX": 0.0343135424364885, "TOVIAZ": 1.7122049435448288, "TOZINAMERAN": 0.0620616476999488, "TRELEGY": 2.612308139962814, "TRULICITY": 1.4737615699466828, "VAXZEVRIA": 0.0264816056038138, "VIAGRA": 2.66454131234433, "XELJANZ": 1.038116217213283, "ZOSTAVAX": 2.0846267244975305, "null": 0.508293753909899}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7221.json
index 544f9621356..b505ada90d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7221.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7221.json
@@ -1 +1 @@
-{"BEOVU": 505.3975975475827, "null": 5.2120338995345215}
\ No newline at end of file
+{"BRAFTOVI": 138.08795302806917, "JETREA": 1078.3765261200688, "null": 0.426540229685208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7222.json
index 2f3c28199db..69fa8799536 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7222.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7222.json
@@ -1 +1 @@
-{"BEOVU": 154.33354710152312, "BROLUCIZUMAB": 366.5736579907837, "EYLEA": 2407.272277697576}
\ No newline at end of file
+{"AIMOVIG": 531.0604864469126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7223.json
index 34e504be195..f566919ceab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7223.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7223.json
@@ -1 +1 @@
-{"EYLEA": 57.26161976336248}
\ No newline at end of file
+{"EYLEA": 251.1990643080358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7224.json
index e613eefdcc9..48d255c549a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7224.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7224.json
@@ -1 +1 @@
-{"null": 2.277708364784209}
\ No newline at end of file
+{"EYLEA": 133.9869974972446, "JETREA": 4742.731750220694, "LANTUS": 2.001116839168535, "VIAGRA": 12.44629385977021, "ZOSTAVAX": 5.734399186954904, "null": 0.4735836582482402}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7225.json
index 90a76d18850..9977cee8e6f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7225.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7225.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 109.29148635965105, "EYLEA": 140.04274260126832}
\ No newline at end of file
+{"null": 0.800415278061176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7226.json
index 8408ed2be0b..2efca812742 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7226.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7226.json
@@ -1 +1 @@
-{"EYLEA": 36.77799147822549, "HUMALOG": 5.77192100095002, "JETREA": 547.28167322381, "LUXTURNA": 709.9379170442716, "PEGASYS": 2.89043483767409, "VIAGRA": 12.81989975830042, "VOTRIENT": 9.127293484818644, "ZOSTAVAX": 6.912282356473393}
\ No newline at end of file
+{"ACTOS": 13.12038077838579, "APIDRA": 8.015776975602865, "AVANDAMET": 26.75152210463802, "AVANDIA": 50.570604294264726, "AVASTIN": 5.243090939831142, "BEOVU": 56.81511750917128, "BRAFTOVI": 13.476829963000965, "COMIRNATY": 0.4283512753339761, "COTELLIC": 18.16314842919592, "EYLEA": 43.90346847102105, "HUMALOG": 4.321612785177637, "JETREA": 65.3759087378149, "KEYTRUDA": 0.7285758153034377, "LANTUS": 2.0775762340818686, "MEKINIST": 4.7703811952517565, "MVASI": 49.39423957211921, "NEVANAC": 78.65877849794477, "PEGASYS": 1.3856567897250325, "SPIKEVAX": 0.2311591026279436, "TOZINAMERAN": 0.3636758690007148, "VAXZEVRIA": 0.2248495676574319, "VIAGRA": 9.445230570750857, "ZOSTAVAX": 1.1033534221186176, "null": 0.5405075105510071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7227.json
index 20f479a20a9..6123db8b86a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7227.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7227.json
@@ -1 +1 @@
-{"EYLEA": 334.74645262170145}
\ No newline at end of file
+{"null": 0.7237271814845543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7228.json
index 7ad5340b98d..03c8d5638d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7228.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7228.json
@@ -1 +1 @@
-{"ARAVA": 1.3456356037395163, "EFAVIRENZ": 68.61216477661677, "HUMIRA": 30.68886444324845, "VIGABATRIN": 363.0742873900012, "null": 1.2944437462716702}
\ No newline at end of file
+{"CELLCEPT": 2.295721166587337, "CICLOSPORIN": 1.7572132848741346, "COMIRNATY": 0.4279273153078921, "COSENTYX": 6.38818257988727, "DEXAMETHASONE": 3.732379924706831, "ELIQUIS": 1.0998863456746122, "GARDASIL": 0.8786734085376903, "LEVOFLOXACIN": 6.5066027731076055, "OPTIMARK": 2.802642456092703, "SPIKEVAX": 0.6490846208726897, "SUFENTANIL": 19.15446590647125, "SUTENT": 1.2305138055385902, "VAXZEVRIA": 0.3046200894284995, "null": 1.8888198210676257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7229.json
index bb0ebb97a8b..ed5dbd54696 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7229.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7229.json
@@ -1 +1 @@
-{"EYLEA": 29.07732837897866, "VIAGRA": 28.04830552645352}
\ No newline at end of file
+{"ARAVA": 2.098789847042928, "COMIRNATY": 0.150414146837319, "EXJADE": 4.332810753745315, "EYLEA": 14.333059867877385, "HUMALOG": 2.8347238038919294, "SILDENAFIL": 17.725295668340177, "VAXZEVRIA": 0.156326647368811, "null": 1.6262141149113092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/723.json
index ec21ed962df..d1740f3fb03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/723.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/723.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 38.85042299652065, "ELIQUIS": 12.510169212244046, "null": 2.208597383915884}
\ No newline at end of file
+{"ADVATE": 709.2331216936611, "ELOCTA": 1392.4633636192832, "HELIXATE": 2526.0794837119424, "HUMAN": 24.89879808887865, "KOGENATE": 3799.027533412679, "KOVALTRY": 1329.062886870339, "OCTOCOG": 4529.024532274634, "null": 2.1249003345748023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7230.json
index 5adc1c4f7e3..1802aedaf62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7230.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7230.json
@@ -1 +1 @@
-{"AVASTIN": 9.221081610538429, "BEOVU": 1085.3663207639063, "BROLUCIZUMAB": 337.6209236249197, "EYLEA": 25.03470553304416, "PEGASYS": 1.6329548913627674, "TOPOTECAN": 66.39421643281551, "VIAGRA": 9.724317708831189}
\ No newline at end of file
+{"AUBAGIO": 9.240141058208, "COMIRNATY": 0.343061547092629, "DEXAMETHASONE": 3.409599116372799, "DOCETAXEL": 28.62631686126565, "FASLODEX": 6.604788663140464, "HERCEPTIN": 20.146285544475266, "IBRANCE": 12.716418761468312, "KISQALI": 18.426697040160583, "SPIKEVAX": 0.1146854229217324, "SUTENT": 1.85122856428322, "TOPOTECAN": 111.006133198286, "TOZINAMERAN": 0.314318857659996, "VAXZEVRIA": 0.1115729329001843, "VOTRIENT": 3.754044316291969, "null": 0.754198836317799}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7231.json
index 78a9324a099..f316207fba5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7231.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7231.json
@@ -1 +1 @@
-{"COMIRNATY": 1.5427850120514424, "EVISTA": 47.79861329191732, "PEGASYS": 2.4073594416780324, "PEGINTRON": 5.725431121513322, "VAXZEVRIA": 2.975279801206809}
\ No newline at end of file
+{"null": 0.6299325826736856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7232.json
index ed1c4713b57..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7232.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7232.json
@@ -1 +1 @@
-{"BEOVU": 1958.8201216085724, "BROLUCIZUMAB": 1058.3681285443824, "EYLEA": 39.34633060336998, "null": 1.1914533657877635}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7233.json
index acd78cdf208..ef5e546a56e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7233.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7233.json
@@ -1 +1 @@
-{"BEOVU": 38.83457347859932, "COMIRNATY": 1.5062037232864214, "COTELLIC": 12.765318213638976, "COVID19": 1.6391588420164938, "EVISTA": 51.98195723432399, "EYLEA": 13.165534798078466, "FASLODEX": 2.0723088938119933, "INTRONA": 15.613812942114516, "MEKINIST": 3.334135001803889, "NEXAVAR": 1.3752686693851064, "PEGASYS": 1.4726458510556122, "PEGINTERFERON": 3.3561024058885565, "PEGINTRON": 11.679088892669055, "RINVOQ": 5.941969111206735, "SILDENAFIL": 5.923870450942348, "TOZINAMERAN": 1.7786634581799314, "VAXZEVRIA": 1.7999610774940071, "VIAGRA": 10.096454587330792}
\ No newline at end of file
+{"BIKTARVY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7234.json
index 8f4031aa3ec..bb71c4e5a15 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7234.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7234.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3246075985892154, "EVISTA": 110.94061222300276, "NEXAVAR": 3.3760254092020348, "PEGASYS": 3.852955619705516, "PEGINTRON": 9.97927039068865, "VAXZEVRIA": 2.345155594627615, "VIAGRA": 11.930644124753902}
\ No newline at end of file
+{"COMIRNATY": 0.2975196945878058, "SPIKEVAX": 16.08806745865082, "null": 0.1545738284502856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7235.json
index 40d8b15b2fe..1179f748b2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7235.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7235.json
@@ -1 +1 @@
-{"TOZINAMERAN": 13.59624061295808}
\ No newline at end of file
+{"ALEMTUZUMAB": 32.93880424044402, "AUBAGIO": 33.03743141943891, "BUPIVACAINE": 13.30367158960146, "CICLOSPORIN": 3.881118250314504, "COMIRNATY": 0.2322523413443501, "FAMPYRA": 14.733252593584226, "LEMTRADA": 87.61157057206633, "METHOTREXATE": 4.13080330349465, "PLEGRIDY": 23.643108950479967, "SPIKEVAX": 0.2648578334994757, "VIGABATRIN": 215.38064940058064, "null": 1.1563778198527697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7236.json
index 9a7db5823cc..3c46a620ccb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7236.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7236.json
@@ -1 +1 @@
-{"ABATACEPT": 7.384913383470053, "ADALIMUMAB": 25.667361731257184, "CICLOSPORIN": 7.967106320598573, "ENBREL": 9.651843362267671, "GANCICLOVIR": 56.1019253052003, "PEGASYS": 3.638104008018494, "PEGINTRON": 4.925367400351732}
\ No newline at end of file
+{"SPIKEVAX": 3.915891187093, "VAXZEVRIA": 6.2335499060464965}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7237.json
index c13e0e8ead9..98db99f1d1f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7237.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7237.json
@@ -1 +1 @@
-{"UMECLIDINIUM": 927.7044778772724, "VIAGRA": 70.52044323766061}
\ No newline at end of file
+{"ABACAVIR": 3.2284729614290035, "ANAKINRA": 10.091366820360111, "ASPARAGINASE": 15.214867007330565, "BEVACIZUMAB": 13.275074355897296, "CICLOSPORIN": 9.762786210681544, "COMIRNATY": 0.1232154072422958, "CYMBALTA": 1.5349874867124909, "GARDASIL": 2.2496140464684977, "GLIBENCLAMIDE": 61.25440741479058, "KALETRA": 6.92243600808856, "LACOSAMIDE": 26.60207033401084, "SPIKEVAX": 0.5276624332653812, "VIGABATRIN": 1295.492678923104, "null": 1.1845161784121905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7238.json
index 44723ebe2ff..bf98f933f88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7238.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7238.json
@@ -1 +1 @@
-{"BUSULFAN": 479.3895253684181}
\ No newline at end of file
+{"SPIKEVAX": 15.550590747291748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7239.json
index f9621ed7b35..0052790810f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7239.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7239.json
@@ -1 +1 @@
-{"TOPOTECAN": 3095.191333454762}
\ No newline at end of file
+{"COMIRNATY": 1.0098470199883007, "MEPOLIZUMAB": 108.32992707146788, "SPIKEVAX": 6.624853611126119}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/724.json
index a95d2327014..f51a7e9bcfa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/724.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/724.json
@@ -1 +1 @@
-{"null": 2.90035005239272}
\ No newline at end of file
+{"ADVATE": 1794.795778416135, "KOGENATE": 4233.530740644854, "null": 0.2974667307030956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7240.json
index ac399435396..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7240.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7240.json
@@ -1 +1 @@
-{"JETREA": 1513.6379296903715, "VIGABATRIN": 2065.285641059615, "null": 2.505632202639742}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7241.json
index a843092c441..faa6172baa6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7241.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7241.json
@@ -1 +1 @@
-{"AIMOVIG": 1.5740211924110483, "APIDRA": 8.404037389713883, "AVANDIA": 1.6907330538744263, "BRAFTOVI": 6.761030131442941, "BYETTA": 3.510448414763377, "COBIMETINIB": 28.878223960038437, "COTELLIC": 14.781719428488843, "DEXAMETHASONE": 1.0832113110212007, "FORXIGA": 3.371922198659732, "HUMALOG": 14.154944278469465, "IBUPROFEN": 2.356505856554259, "INSULIN": 5.291521094476115, "INTRONA": 33.46814813320723, "LANTUS": 18.3638935691191, "LEVEMIR": 5.4030603618121535, "MEKINIST": 4.503406878502394, "OZEMPIC": 25.79569981755616, "PEGASYS": 13.870868379099276, "PEGINTERFERON": 46.848390521921615, "PEGINTRON": 30.705000610015883, "RIBAVIRIN": 9.647398177445456, "TRESIBA": 23.98402611984035, "TRULICITY": 3.702058477784784}
\ No newline at end of file
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7242.json
index b9235265184..5003122d937 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7242.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7242.json
@@ -1 +1 @@
-{"BUSULFAN": 209.98767731643892}
\ No newline at end of file
+{"SPIKEVAX": 11.323023439499815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7243.json
index 0c0109875ba..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7243.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7243.json
@@ -1 +1 @@
-{"null": 1.2371071133664855}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7244.json
index c70a0b5dc11..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7244.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7244.json
@@ -1 +1 @@
-{"null": 2.757485007817944}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7245.json
index 262e17416b2..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7245.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7245.json
@@ -1 +1 @@
-{"LANTUS": 20.994863863076667}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7246.json
index f488584e472..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7246.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7246.json
@@ -1 +1 @@
-{"null": 1.7436960170364368}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7247.json
index f0ad5b64d03..92b0750930f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7247.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7247.json
@@ -1 +1 @@
-{"CANNABIDIOL": 2835.8261528496346}
\ No newline at end of file
+{"ATRIPLA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7248.json
index 53b463f500f..4008fbb9803 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7248.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7248.json
@@ -1 +1 @@
-{"KEPPRA": 13.164849307692906, "TRUVADA": 5.59164034990184, "null": 3.850560056964408}
\ No newline at end of file
+{"ABILIFY": 4.745339845794723, "ARIPIPRAZOLE": 1.2909378559468965, "ATRIPLA": 0.2532538543614911, "BIKTARVY": 3.869531464238956, "BRINTELLIX": 4.344682599792273, "CHAMPIX": 8.878504872299018, "COMIRNATY": 0.050158289636206, "COSENTYX": 0.5797282211988961, "CYMBALTA": 3.3688885479285724, "DULOXETINE": 7.221267848681291, "ESOMEPRAZOLE": 101.10216788144834, "FENTANYL": 0.8247681765055961, "FORSTEO": 0.8524513345661928, "GARDASIL": 2.5541108282856504, "HUMALOG": 0.4793417963814563, "IBUPROFEN": 2.246361793521384, "KEPPRA": 4.897866108310845, "LATUDA": 10.670326275528408, "LEVETIRACETAM": 4.97187036849143, "OLANZAPINE": 5.486867594476901, "OPTIMARK": 1.9910250709408768, "PEGASYS": 2.599668333410378, "PEGINTERFERON": 2.7815453689361043, "PEGINTRON": 1.1258618332135972, "SPIKEVAX": 0.1117208394134771, "STELARA": 0.8701456840441194, "STRIBILD": 0.7630134662882235, "SUBOXONE": 4.833808813131921, "TIVICAY": 16.01999119556906, "TOZINAMERAN": 0.2802006153136004, "VAXZEVRIA": 0.0772197343839172, "XELJANZ": 1.360510896915483, "ZOSTAVAX": 8.639191892383108, "ZYPREXA": 3.316289176196924, "null": 1.6845040852401287}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7249.json
index 37b092444fb..fdcb57d8d4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7249.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7249.json
@@ -1 +1 @@
-{"null": 1.694014173869416}
\ No newline at end of file
+{"CELLCEPT": 2.301746654608104, "CICLOSPORIN": 1.0224440674252924, "CIMZIA": 0.5052346398880964, "COMIRNATY": 0.0320830635132618, "FENTANYL": 1.193681567433429, "GARDASIL": 0.7949954436961116, "JANUMET": 1.9532060118784136, "KEPPRA": 0.9173874287389246, "LATUDA": 2.478510551521283, "LEVETIRACETAM": 2.7857197542984866, "NOXAFIL": 10.608870916373665, "RINVOQ": 5.823319031513019, "TRUVADA": 0.5579471144686566, "null": 6.960891961148885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/725.json
index d3238227f69..4efe31792c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/725.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/725.json
@@ -1 +1 @@
-{"BRIVIACT": 65.32405116475624, "GARDASIL": 3.1818444584995884, "KEPPRA": 12.088804075393584, "LEVETIRACETAM": 45.35319020774524, "null": 1.6591405617730022}
\ No newline at end of file
+{"ELIQUIS": 115.4731606411558}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7250.json
index 8def0081310..e19fc23d833 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7250.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7250.json
@@ -1 +1 @@
-{"SILODOSIN": 777.6218048306735, "SILODYX": 2112.8729472760488, "UROREC": 2970.1814121982547, "null": 1.8482979659529637}
\ No newline at end of file
+{"null": 1.7013307775893165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7251.json
index 40dd932d10b..54ce361be21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7251.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7251.json
@@ -1 +1 @@
-{"KEYTRUDA": 5.475377659097775, "null": 3.793581172214924}
\ No newline at end of file
+{"null": 4.29790114419221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7252.json
index e1d268c80f3..eaa6962e513 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7252.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7252.json
@@ -1 +1 @@
-{"APREMILAST": 19.220423831318243, "BRILIQUE": 6.06720148205852, "BUDESONIDE": 1.337538601780646, "CLOPIDOGREL": 18.09341681949948, "EFIENT": 27.170701029616268, "ELIQUIS": 6.36052257700616, "ENOXAPARIN": 108.03102825230611, "PLAVIX": 11.33185287564944, "XARELTO": 10.66453769730496, "null": 3.025162724547804}
\ No newline at end of file
+{"HUMALOG": 48.65335160647518, "null": 0.4451908553052324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7253.json
index 9deb6d0c1b2..1b3b5b02fe4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7253.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7253.json
@@ -1 +1 @@
-{"APIXABAN": 1.8617676339956517, "BUDESONIDE": 1.1457295240247374, "CLOPIDOGREL": 17.724427985785972, "EFIENT": 28.871328669811827, "ELIQUIS": 5.047299853825314, "ENOXAPARIN": 34.69276445919441, "INTEGRILIN": 163.9798936559638, "PLAVIX": 16.624812849855513, "XARELTO": 13.873805144048994, "null": 3.373220611658708}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7254.json
index 23768dca6ae..b2b6b75ad94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7254.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7254.json
@@ -1 +1 @@
-{"ADCIRCA": 103.74743064531977, "NEXAVAR": 22.06095574041033, "STIVARGA": 16.280993968272302}
\ No newline at end of file
+{"CELSENTRI": 314.199920891648, "COMBIVIR": 60.12535236189317, "null": 2.0197843529411643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7255.json
index beaf798c550..3a4a4fe42ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7255.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7255.json
@@ -1 +1 @@
-{"null": 1.569900760278023}
\ No newline at end of file
+{"null": 4.930909573735763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7256.json
index 03872f0a08b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7256.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7256.json
@@ -1 +1 @@
-{"COMIRNATY": 2.6927479425134058, "VAXZEVRIA": 3.434087229227952}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7257.json
index 2e0f808dfb9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7257.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7257.json
@@ -1 +1 @@
-{"AVAMYS": 94.17905426529416, "BUDESONIDE": 37.98496758565716, "DULOXETINE": 368.35045376148594, "MEPOLIZUMAB": 165.91041215958182, "NUCALA": 13.911099665157383}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7258.json
index 534adffb61e..dd5b900bf54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7258.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7258.json
@@ -1 +1 @@
-{"AIMOVIG": 5.032540246222401, "CHAMPIX": 4.025814187258132, "CICLOSPORIN": 3.1630603196520526, "DULOXETINE": 34.862011505669614, "ERENUMAB": 84.96753267042453, "null": 2.247088394971932}
\ No newline at end of file
+{"VIAGRA": 52.14127593129213, "null": 6.261144900077794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7259.json
index 54c64bbc1ba..352d5b4229a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7259.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7259.json
@@ -1 +1 @@
-{"null": 1.1228291695147434}
\ No newline at end of file
+{"VIAGRA": 33.506478751547284, "null": 3.2209407144768694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/726.json
index e59d1179c5b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/726.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/726.json
@@ -1 +1 @@
-{"null": 1.0493486682659243}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7260.json
index a7b2c53a181..b0c7925e37f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7260.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7260.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 41.56394602037711, "null": 2.08356463408125}
\ No newline at end of file
+{"PEGASYS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7261.json
index 22bd2a0e8a6..5b0d758dbfa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7261.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7261.json
@@ -1 +1 @@
-{"METHOTREXATE": 595.4633302978953}
\ No newline at end of file
+{"null": 3.72230508660848}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7262.json
index 8e0fe46e5cd..c12d274b236 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7262.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7262.json
@@ -1 +1 @@
-{"ABILIFY": 2.330241846867506, "ABIRATERONE": 27.94208360278053, "ACTOS": 2.3574396541673592, "ACTRAPID": 1.222535869209162, "ADENURIC": 5.0221998599265705, "AERIUS": 4.131883655065865, "ALLI": 17.955012444715173, "APROVEL": 3.720166999893921, "ARIPIPRAZOLE": 1.2984870143686706, "ATAZANAVIR": 1.400315100994585, "AVONEX": 3.440910591764494, "BARACLUDE": 1.25802137483908, "BENZODIAZEPINE": 7.114819133205719, "BRAFTOVI": 1.965340398575522, "BRILIQUE": 4.015422845178487, "BUPRENORPHINE": 1.182465572655162, "CANCIDAS": 1.1405029075635182, "CICLOSPORIN": 3.356471362435037, "COAPROVEL": 2.545874650105217, "COMBIVIR": 1.3689638220536138, "COMTAN": 5.59982229076503, "COMTESS": 10.68367494008711, "COTELLIC": 5.010526842130283, "CRIXIVAN": 1.7203077304974577, "CUBICIN": 29.34515103572772, "DABRAFENIB": 2.4133314712281444, "DACLATASVIR": 2.1838001674814382, "DAPTOMYCIN": 9.308087919250143, "DESCOVY": 1.833067745863858, "DULOXETINE": 2.137670244165941, "EBIXA": 1.868713641994694, "EMTRICITABINE": 1.792111931505044, "ENTACAPONE": 3.907979611635122, "ENTECAVIR": 3.788695308583685, "ESOMEPRAZOLE": 7.04782341843211, "EXVIERA": 1.8247668453879329, "FEBUXOSTAT": 13.469588248387131, "FENTANYL": 2.507538097464725, "GENVOYA": 2.3981420925930146, "GLUCAGON": 7.381719612016032, "H2": 216.35069088426985, "HARVONI": 1.1658342067166805, "HEPSERA": 1.2411776748030043, "HYDROCORTISONE": 1.6708639241383751, "IBUPROFEN": 1.1462762600304142, "INVEGA": 2.0660382432029314, "INVIRASE": 3.908097216322319, "INVOKANA": 1.0395231314603586, "IPILIMUMAB": 1.1710384373800304, "IRBESARTAN": 3.0272445906373364, "ISENTRESS": 5.519433782463867, "JANUVIA": 2.0986702847123646, "KALETRA": 2.731748008480644, "KEPPRA": 1.561069978724518, "KEYTRUDA": 1.1064127793062155, "LATUDA": 1.0835518134969415, "LEVETIRACETAM": 3.298785042958482, "LEVOFLOXACIN": 2.5545417796052305, "LOPINAVIR": 3.0968893244153524, "LYRICA": 2.883749696193728, "MANNITOL": 3.344413496146685, "MEKINIST": 5.105861713078274, "METFORMIN": 2.844466851094132, "MICARDIS": 5.05372756229684, "MIDAZOLAM": 3.750315903647772, "NORVIR": 3.186967632131719, "NOT": 1.7220301290421312, "NOVONORM": 3.2965332850104714, "NOXAFIL": 2.626002675550662, "OCALIVA": 1.438552848832064, "OLANZAPINE": 4.960702451954989, "OPDIVO": 1.546611642837582, "ORKAMBI": 1.5280506567034613, "OSELTAMIVIR": 2.967152912319696, "PAZOPANIB": 1.0063329705865474, "PEGINTRON": 1.438044181885073, "PLAVIX": 1.1776204553565677, "POSACONAZOLE": 4.701720694925154, "PREGABALIN": 3.397886671031312, "PROPRANOLOL": 2.1042276538279827, "RANEXA": 3.551616840388013, "RANOLAZINE": 4.685660491757384, "REYATAZ": 1.7496726398784666, "RISPERIDONE": 2.862704163174849, "RIVAROXABAN": 2.330031726648471, "SIFROL": 2.720041660178831, "SOVALDI": 1.2478141442424062, "STALEVO": 2.870390291627024, "SUFENTANIL": 1.127654624196125, "SYCREST": 7.34031382418971, "TAMIFLU": 3.450854041752684, "TELMISARTAN": 2.479783272090896, "TESTOSTERONE": 1.685232622420703, "TICAGRELOR": 12.100416845817044, "TIVICAY": 1.4099638075115313, "TRABECTEDIN": 36.30981724335528, "TRIUMEQ": 2.276912589685794, "VFEND": 3.031479370740858, "VILDAGLIPTIN": 3.732917095042711, "VIMPAT": 1.1478598294588809, "VIREAD": 1.133650374579738, "VORICONAZOLE": 2.861615606029979, "XEPLION": 11.90145791408296, "YONDELIS": 49.58194982393093, "ZYPREXA": 6.191222633861633, "ZYTIGA": 11.56432057170765, "null": 3.246701802077788}
\ No newline at end of file
+{"null": 1.308269228709178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7263.json
index ba2edde289c..3f27e8f206c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7263.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7263.json
@@ -1 +1 @@
-{"VOTRIENT": 48.498195511699386, "null": 1.248888307616718}
\ No newline at end of file
+{"AFINITOR": 10.655674058665232, "BYETTA": 77.72463427589034, "JANUMET": 28.829174552005107, "KEYTRUDA": 15.440631322205238, "NEXAVAR": 9.704594799694252, "null": 0.2956858591889576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7264.json
index 5dcf55d79d0..d6638b7cc3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7264.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7264.json
@@ -1 +1 @@
-{"JETREA": 1503.9515480011232}
\ No newline at end of file
+{"VOTRIENT": 1165.1732247638752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7265.json
index 57f6fb37459..9ae3cdeeb51 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7265.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7265.json
@@ -1 +1 @@
-{"ABILIFY": 2170.426636709448}
\ No newline at end of file
+{"CANNABIDIOL": 6173.011979038408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7266.json
index 7b59a261532..da6df5d380d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7266.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7266.json
@@ -1 +1 @@
-{"COMIRNATY": 2.89711670611894, "COMTAN": 14.523453796676922, "COSENTYX": 3.4180364181895464, "ENTRESTO": 1.8399301374357868, "FASENRA": 4.9959519892270565, "FORSTEO": 5.344742168332026, "GARDASIL": 1.7910520726580763, "KEYTRUDA": 2.151300969877792, "METHOTREXATE": 2.565423139816607, "RINVOQ": 6.098823659678434, "SIMPONI": 5.415924955997225, "SPIKEVAX": 1.2986572697268757, "STELARA": 1.238373130474084, "XOLAIR": 1.2976692911900338}
\ No newline at end of file
+{"CICLOSPORIN": 43.56129173253558, "null": 0.4223505548679677}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7267.json
index 7d1d25f035b..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7267.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7267.json
@@ -1 +1 @@
-{"ABATACEPT": 13.66114112684857, "ADALIMUMAB": 37.43060745846528, "AMINOSALICYLIC": 5.271767300810192, "APREMILAST": 156.28610650017237, "ARAVA": 31.35657492616648, "CIMZIA": 12.880976966082926, "COSENTYX": 6.047443122014809, "RITUXIMAB": 1.8493919430177044}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7268.json
index c8f5d9445e1..6a072a7a127 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7268.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7268.json
@@ -1 +1 @@
-{"null": 1.2060823558289395}
\ No newline at end of file
+{"KEYTRUDA": 40.064834907249406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7269.json
index 381ac988505..f07a0f21c9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7269.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7269.json
@@ -1 +1 @@
-{"ABACAVIR": 13.68568399991304, "ABATACEPT": 6.104104497081946, "ACLASTA": 6.655821182683525, "ADALIMUMAB": 7.229524863126858, "ANAKINRA": 14.97446116101984, "APREMILAST": 7.7303399343699954, "ARAVA": 26.075039105980768, "AZATHIOPRINE": 1.221340256532483, "CELECOXIB": 1.4179978667143336, "CERTOLIZUMAB": 9.303008597753555, "CIMZIA": 19.28403753308313, "COSENTYX": 2.4841217416482557, "DACLIZUMAB": 23.24494276485305, "ENBREL": 24.13359677623724, "ERELZI": 13.218793550920749, "ETANERCEPT": 5.631322626424913, "GOLIMUMAB": 6.935613258051929, "HUMIRA": 9.252504710501295, "KEVZARA": 11.631571390001218, "LEFLUNOMIDE": 13.263950877693098, "METFORMIN": 1.6344636288171668, "METHOTREXATE": 8.401388559503568, "ORENCIA": 11.052196031653216, "REMICADE": 2.638624540669191, "RINVOQ": 7.204183789109653, "RITUXIMAB": 2.361410234758249, "ROACTEMRA": 3.88898519919823, "SIMPONI": 11.598284237768317, "TOCILIZUMAB": 1.9514697256935176, "TOFACITINIB": 4.11645173799976, "XELJANZ": 9.684068297605616}
\ No newline at end of file
+{"SUTENT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/727.json
index b5659bfc687..faa6172baa6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/727.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/727.json
@@ -1 +1 @@
-{"METHOTREXATE": 153.53550276360943}
\ No newline at end of file
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7270.json
index b16c478adef..ef80608db89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7270.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7270.json
@@ -1 +1 @@
-{"ARAVA": 2.882240675672327, "COMIRNATY": 1.046620580296881, "SIMPONI": 11.118534032085968, "XELJANZ": 4.314748161567954}
\ No newline at end of file
+{"METHOTREXATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7271.json
index cf031e2fcd6..07f8d627ef0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7271.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7271.json
@@ -1 +1 @@
-{"ARAVA": 54.05435480938698, "CICLOSPORIN": 16.064130920802604, "CIMZIA": 32.11747857238719, "ENBREL": 17.478297757557034}
\ No newline at end of file
+{"ARAVA": 1.199557498586069, "COMIRNATY": 0.1634917925509971, "SOLIRIS": 23.629400612034257, "VAXZEVRIA": 0.1797574678334908, "null": 0.9207246315041088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7272.json
index c1cbabdbedc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7272.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7272.json
@@ -1 +1 @@
-{"ABATACEPT": 13.04151135261995, "ADALIMUMAB": 24.497784720931406, "ANAKINRA": 19.394685961484104, "APREMILAST": 69.50122848091762, "ARAVA": 57.678731259422975, "BUDESONIDE": 1.8612535729073556, "CIMZIA": 3.0033879385232582, "COSENTYX": 2.9875583937413666, "ENBREL": 7.463582862760253, "HUMIRA": 6.0941831963380535, "METHOTREXATE": 2.507160281205742, "RITUXIMAB": 2.055448615396435}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7273.json
index 886b2fccbc8..2f072876afa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7273.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7273.json
@@ -1 +1 @@
-{"ABATACEPT": 15.62240243767165, "ADALIMUMAB": 9.477363536977917, "ARAVA": 7.327843084994484, "ENBREL": 26.565900698901224, "XELJANZ": 15.22532435086121}
\ No newline at end of file
+{"AVAMYS": 321.2684470050152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7274.json
index 5b8c8729528..0b8c1ad3e5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7274.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7274.json
@@ -1 +1 @@
-{"ABATACEPT": 12.432784570423705, "ADALIMUMAB": 4.629907498506006, "ARAVA": 34.11991791423619, "CICLOSPORIN": 3.744934440190772, "CIMZIA": 1.9560334681306064, "COSENTYX": 5.595523023708395, "ENBREL": 69.46164349701796, "LEFLUNOMIDE": 22.93922105038044, "METHOTREXATE": 17.952708853271382, "ROACTEMRA": 15.546423284824536, "XELJANZ": 3.206396668823501}
\ No newline at end of file
+{"ADALIMUMAB": 0.1444262775067088, "ALEMTUZUMAB": 1.217201578161178, "ARAVA": 0.1827730523820047, "AUBAGIO": 1.136617288194451, "BINIMETINIB": 46.72571709494515, "BRAFTOVI": 3.245991038295499, "BUDESONIDE": 0.5271086285668077, "BYDUREON": 1.7168563082999573, "BYETTA": 0.6035858265002841, "CELLCEPT": 1.6687293501557554, "CIALIS": 1030.757229570867, "CICLOSPORIN": 1.011135776489467, "CIMZIA": 1.3079613145641544, "COMIRNATY": 0.0314990052789011, "COSENTYX": 2.523722196668478, "COTELLIC": 5.734243465443444, "DABRAFENIB": 62.77887682052799, "DEXAMETHASONE": 0.5326464016367493, "ELIQUIS": 0.2414094461050772, "ENBREL": 2.272604208523304, "ENTYVIO": 1.957017402844709, "FAMPYRA": 1.3251815223999008, "FORSTEO": 0.7113783969449609, "HUMALOG": 0.3689763133955194, "HUMIRA": 2.1072076408577973, "IBRANCE": 0.2600132983856259, "IPILIMUMAB": 2.930529179041703, "JAKAVI": 1.124716452867189, "JARDIANCE": 0.4028250453522173, "KEYTRUDA": 0.4493766055252264, "LANTUS": 0.4409444580876657, "LEMTRADA": 2.076460599897214, "LEVITRA": 100.69410941559936, "MEKINIST": 64.0017770057119, "METHOTREXATE": 0.4983324680971816, "MYCOPHENOLATE": 2.360610977139317, "NEXAVAR": 0.3193912414895124, "NPLATE": 1.299167524313558, "NUCALA": 0.4600861051295339, "PEGINTRON": 0.7120806438372826, "REMICADE": 4.181793079487493, "RINVOQ": 3.76671441919269, "ROACTEMRA": 6.833483133665967, "SILDENAFIL": 10.870041311769825, "SIMPONI": 4.123749254333951, "SOLIRIS": 0.7808605812984407, "STELARA": 6.71005929378598, "SUTENT": 0.2567443424583588, "TADALAFIL": 27.122319976752102, "TAFINLAR": 26.51803200313268, "TREMFYA": 3.0969463390329564, "VALSARTAN": 4.812103877481853, "VAXZEVRIA": 0.0202001037771479, "VIAGRA": 186.55452091965492, "XELJANZ": 2.540562461121192, "XOLAIR": 2.1604329481759623, "YERVOY": 2.4404107321332678, "ZELBORAF": 22.42615015582018, "ZOSTAVAX": 1.0410888590100538, "null": 0.3436967609475874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7275.json
index 5e0eb2f0c52..4e455f2886e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7275.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7275.json
@@ -1 +1 @@
-{"SIMPONI": 69.44604739646384}
\ No newline at end of file
+{"CIALIS": 2984.2853286942864, "CIMZIA": 1.1743262163765371, "LEVITRA": 326.721474720663, "SPIKEVAX": 0.1076654014173211, "STELARA": 5.304794719412566, "VIAGRA": 304.06768829500163, "null": 0.0386815586356351}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7276.json
index 64f7f9924cf..630f84936a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7276.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7276.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 44.787682709061805, "AVAMYS": 25.91224553379479, "BAQSIMI": 681.5825439883189, "COSENTYX": 2.0550116016899658, "SUTENT": 1.5856093919074934, "null": 1.431944212627485}
\ No newline at end of file
+{"CIALIS": 10055.556989065251, "VIAGRA": 74.9636904094196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7277.json
index 1d0217ce724..ff2271e02e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7277.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7277.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.0673213626106255, "ANORO": 1.6431313757228698, "AVAMYS": 4.128318354387429, "BENLYSTA": 2.836004513993525, "COMIRNATY": 1.3912336947383526, "COSENTYX": 2.0949740769619307, "ENTYVIO": 1.0188400048408437, "EXFORGE": 1.2733096845663208, "FASENRA": 4.311639311834452, "GARDASIL": 1.0031865481629754, "HIZENTRA": 1.130725021026871, "INFANRIX": 3.098262815554304, "MEPOLIZUMAB": 7.544861199545633, "METHOTREXATE": 1.7459271776240728, "MICARDIS": 1.1547031742143106, "MMRVAXPRO": 5.836410905507463, "NIMENRIX": 3.795879919456345, "NUCALA": 4.082721937641772, "OMALIZUMAB": 1.1169308282885306, "PEGINTRON": 1.1755372333269023, "PRIVIGEN": 1.5918296078122924, "RELVAR": 5.311119912738873, "RINVOQ": 1.1824692013234974, "ROTATEQ": 3.664601465994487, "SIMPONI": 2.637103055920506, "SYNAGIS": 6.431888217628884, "TRELEGY": 1.412323998661691, "VAXZEVRIA": 1.736592565898026, "XOLAIR": 2.456566342968939, "ZOSTAVAX": 1.4934049611427829, "null": 1.3841217812769775}
\ No newline at end of file
+{"CIALIS": 6699.82115394077, "VIAGRA": 108.97182328947208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7278.json
index 5e1504d60b7..f735de12004 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7278.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7278.json
@@ -1 +1 @@
-{"ACLIDINIUM": 73.9618636737396, "ANORO": 4.194067754478722, "APIXABAN": 119.8882808773418, "AVAMYS": 20.09440589859913, "BUDESONIDE": 28.37765729441456, "EFAVIRENZ": 5.643928260125612, "ELIQUIS": 3.077997175193168, "ESOMEPRAZOLE": 5.4439130683398655, "FLUTICASONE": 11.779245709294711, "GARDASIL": 1.0269842957852215, "GLYCOPYRRONIUM": 175.31064955010729, "HUMALOG": 2.931694052766853, "KALETRA": 2.2084972018753803, "MEPOLIZUMAB": 1.3814719000682791, "NUCALA": 33.946734373763285, "OMALIZUMAB": 1.366982892206464, "XOLAIR": 1.7830712801293769, "ZOSTAVAX": 13.313651559695588}
\ No newline at end of file
+{"CIALIS": 3313.018374028092, "MEKINIST": 54.35610889563307, "VIAGRA": 115.61467380398553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7279.json
index a76a7eec579..d2591c01f10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7279.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7279.json
@@ -1 +1 @@
-{"null": 2.5907254632306738}
\ No newline at end of file
+{"CIALIS": 2615.4602735927106, "DABRAFENIB": 110.14107887544486, "MEKINIST": 182.91229607400115, "VIAGRA": 116.42887587058576, "null": 0.0538514220639366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/728.json
index 5216b0043e1..2bf6ee5f2fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/728.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/728.json
@@ -1 +1 @@
-{"null": 3.787364818909382}
\ No newline at end of file
+{"INSULIN": 46.94203452299474, "null": 0.2278830482753686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7280.json
index 7458dcc2d2b..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7280.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7280.json
@@ -1 +1 @@
-{"ACLIDINIUM": 1.479722656044943, "AMBRISENTAN": 1.7413501519425074, "ANORO": 2.513978171807507, "APIXABAN": 4.085998878789547, "ASPARAGINASE": 2.687526536131911, "AVAMYS": 11.883770938545128, "BENLYSTA": 2.959161850835874, "BEXSERO": 1.3111185337195572, "BUDESONIDE": 4.8169666719002615, "COMIRNATY": 1.335954333144305, "COSENTYX": 2.543777205374451, "COVID19": 1.6366351727812862, "CYTARABINE": 1.511472157814521, "DARZALEX": 3.3710487144258328, "DULOXETINE": 1.1529512690620694, "ENTRESTO": 1.0011132611294908, "ESBRIET": 1.5293190585742271, "EVEROLIMUS": 1.1376953351803554, "FASENRA": 1.4438712306832675, "FLUCELVAX": 5.86962851396378, "FLUTICASONE": 4.650191328568088, "GALAFOLD": 5.519666429598175, "HUMIRA": 1.5150745170603217, "IBRANCE": 1.6593288062461418, "INCRUSE": 2.681956772739372, "INFANRIX": 1.2178002096770486, "INSULIN": 2.6004735713794456, "IRON": 1.707553473408567, "KAFTRIO": 1.126442700796371, "KESIMPTA": 3.2106796698796525, "LEFLUNOMIDE": 1.4482416813482184, "MENVEO": 1.5956148093959306, "MEPOLIZUMAB": 5.1193576864398125, "METHOTREXATE": 1.0872625425260984, "MMRVAXPRO": 2.561623267502285, "NAGLAZYME": 8.644132215498562, "NIMENRIX": 1.878163654745356, "NUCALA": 7.345957782910604, "OCRELIZUMAB": 3.939346059938994, "OFEV": 1.219960966945714, "OMALIZUMAB": 3.647646075692884, "OPSUMIT": 1.4663202516578542, "PREVENAR": 5.32850482029045, "RELVAR": 4.4430348512079245, "REVATIO": 1.515499202712625, "RITUXIMAB": 1.318497030344414, "ROTATEQ": 1.4625855363405678, "SUBOXONE": 1.2418831002472588, "SYNAGIS": 7.858839977660247, "SYNFLORIX": 6.683469626978567, "TAMIFLU": 1.1142478344118862, "TOPOTECAN": 1.6799586635558963, "TOZINAMERAN": 3.172850183630211, "TRELEGY": 2.118557120821474, "XELJANZ": 2.3054221947515545, "XOLAIR": 2.344692654500089}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7281.json
index a76a7eec579..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7281.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7281.json
@@ -1 +1 @@
-{"null": 2.5907254632306738}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7282.json
index 6eceb64bc33..a711a2dea06 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7282.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7282.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 7.300187238670862, "ASPARAGINASE": 102.53648638889446, "BENRALIZUMAB": 93.0733056409477, "BUSULFAN": 17.005345014307576, "CICLOSPORIN": 1.6682922380202754, "CYTARABINE": 49.558251283999525, "ORKAMBI": 27.60171613281335, "SPINRAZA": 215.56437940435765, "SYNAGIS": 180.1941662888103, "TRACLEER": 11.829268524495577}
\ No newline at end of file
+{"JANUMET": 64.54843315884236, "null": 0.5137590138209702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7283.json
index f36f8b82095..b082204dfd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7283.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7283.json
@@ -1 +1 @@
-{"CICLOSPORIN": 31.862419839963398}
\ No newline at end of file
+{"null": 0.6567000203142764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7284.json
index 677c6bc400e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7284.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7284.json
@@ -1 +1 @@
-{"BIKTARVY": 21.339886093385932, "BUDESONIDE": 5.614708455050379, "CLOPIDOGREL": 3.256334380081722, "MELATONIN": 36.05801041979489, "NUCALA": 8.904008941358247, "XOLAIR": 9.19097870107115, "null": 1.4723713777804197}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7285.json
index 4ab43e888fc..8fdc65842d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7285.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7285.json
@@ -1 +1 @@
-{"BUPIVACAINE": 227.1405988061508, "FENTANYL": 31.23020350990429, "null": 2.976063820706978}
\ No newline at end of file
+{"GAZYVARO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7286.json
index 88a1d2dbdf5..426384360df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7286.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7286.json
@@ -1 +1 @@
-{"null": 1.0966247451530042}
\ No newline at end of file
+{"OLYSIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7287.json
index d7b9817864e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7287.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7287.json
@@ -1 +1 @@
-{"AIMOVIG": 4.934335273085088, "ATRIPLA": 14.367268478849308, "BONVIVA": 3.260998281005002, "BUPRENORPHINE": 2.6467355133248778, "DEXAMETHASONE": 1.3549896165666775, "ELIQUIS": 1.456004899145919, "ESBRIET": 2.731369791669115, "EVENITY": 5.490175872880482, "EVISTA": 10.445020557408972, "EXFORGE": 1.891952762462656, "FASLODEX": 1.7262508037696926, "FIRDAPSE": 10.17001388322952, "FORSTEO": 5.246461201054666, "HEPSERA": 16.381379774631004, "HUMALOG": 2.152843009152915, "IBRANCE": 1.955708315640984, "INCRUSE": 6.063877870495214, "IRON": 4.449471708752141, "LANTUS": 1.3921499404127111, "MICARDIS": 1.209005408339026, "NINLARO": 3.5169239498910576, "NORVIR": 2.2766374056063348, "REVATIO": 1.4515337919337574, "SIMPONI": 1.4384726630115263, "STRIBILD": 12.038808566425972, "SUBOXONE": 5.800062484734363, "TRELEGY": 3.3974485563779275, "TREMFYA": 1.4319974364640715, "TRUVADA": 10.124787128807911, "VIAGRA": 1.8187403747344768, "VIMPAT": 1.5485485129082572, "VIREAD": 7.506233451525775, "XELJANZ": 4.5029789902352455, "XOLAIR": 1.4688985217270385, "XTANDI": 2.897442286644785}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7288.json
index 7a4782d1b81..64f4f609460 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7288.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7288.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 34.21538925188337, "CYTARABINE": 14.632347746663056, "DOXORUBICIN": 109.25620126299856, "IMBRUVICA": 176.97983750317442, "RITUXIMAB": 50.98188402297676, "VENCLYXTO": 427.98059946162687, "VENETOCLAX": 582.5897667451836}
\ No newline at end of file
+{"null": 0.8080245494647719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7289.json
index f251bd84b21..fa6cafe7000 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7289.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7289.json
@@ -1 +1 @@
-{"null": 2.489100169809212}
\ No newline at end of file
+{"null": 0.8530211231425517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/729.json
index 7ea0372bcdb..8b5194a1f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/729.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/729.json
@@ -1 +1 @@
-{"ENALAPRIL": 775.9646085531555, "ENTRESTO": 21.46485247400659, "null": 1.175612621368215}
\ No newline at end of file
+{"LEMTRADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7290.json
index addcf2accb8..a1c1784cea5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7290.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7290.json
@@ -1 +1 @@
-{"null": 7.9823439037603166}
\ No newline at end of file
+{"KEYTRUDA": 42.1456158954154}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7291.json
index 883eb5a93d1..2f2fed57782 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7291.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7291.json
@@ -1 +1 @@
-{"BUMETANIDE": 556.5390627621568, "IBUPROFEN": 68.35155925657848}
\ No newline at end of file
+{"ABEMACICLIB": 17.71103368606872, "ABIRATERONE": 9.80531146295762, "ABRAXANE": 23.199986162423457, "ADCETRIS": 2.500141335478064, "AFATINIB": 10.974094265330796, "AFINITOR": 28.990484085185503, "AFLIBERCEPT": 4.271566426015454, "ALECTINIB": 15.476810263090869, "ALIMTA": 22.685301763025528, "ALPELISIB": 22.57815466307848, "APALUTAMIDE": 5.112240598587916, "ARANESP": 0.2880078847593214, "ASPARAGINASE": 0.8467772376657315, "ATEZOLIZUMAB": 4.6919584958277145, "AVASTIN": 4.916407068228724, "AXICABTAGENE": 1.3611264431597094, "AXITINIB": 19.181196921592857, "AZACITIDINE": 2.0528288742589726, "BEVACIZUMAB": 8.32715716398514, "BINIMETINIB": 9.035119602991468, "BLINATUMOMAB": 3.878533800941676, "BORTEZOMIB": 2.1469346685459314, "BOSULIF": 0.296668904609715, "BOSUTINIB": 3.682652636205566, "BRAFTOVI": 2.8503229898888818, "BRENTUXIMAB": 12.169908275871409, "BREYANZI": 11.064216574603396, "BUSULFAN": 0.9046559540947138, "CABAZITAXEL": 23.737309177638537, "CABOMETYX": 14.661974159717865, 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0.2408782433954145, "TAFINLAR": 10.074603566996371, "TAGRISSO": 23.07686060217942, "TASIGNA": 4.432011216874221, "TAXOTERE": 2.4246877508444062, "TEGAFUR": 2.341822028937473, "TEMODAL": 3.857710699635272, "TEMOZOLOMIDE": 9.587188952169704, "THALIDOMIDE": 0.63576701561307, "THIOTEPA": 1.5404932203128563, "TISAGENLECLEUCEL": 2.229553208403124, "TOPOTECAN": 6.125014988030871, "TRAMETINIB": 25.4187534355958, "TRASTUZUMAB": 2.757867358889308, "TRELEGY": 0.0971963408758757, "TRISENOX": 1.6940306376611938, "TRODELVY": 0.6170621205275674, "VEMURAFENIB": 2.600347477976096, "VENETOCLAX": 0.3801193616045901, "VOTRIENT": 13.28520716586008, "XELODA": 1.0850365834327422, "XGEVA": 7.224431708774694, "XOFIGO": 3.83177098721678, "XTANDI": 33.76219057946895, "YERVOY": 52.809348812424254, "ZELBORAF": 1.1677659782070355, "ZOLEDRONIC": 7.868406437144278, "ZOMETA": 5.594598733873204, "null": 0.267118176044065}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7292.json
index cfaa3e56a31..5964ec2bdf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7292.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7292.json
@@ -1 +1 @@
-{"ENTRESTO": 21.581307794944863, "null": 1.6089317194115926}
\ No newline at end of file
+{"EVISTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7293.json
index a4e83838694..848da365ecf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7293.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7293.json
@@ -1 +1 @@
-{"ALENDRONATE": 12944.022537291452, "APIXABAN": 307.4488206995459}
\ No newline at end of file
+{"JANUVIA": 17.584144466350097, "null": 0.4735950626195464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7294.json
index 1ffebc51a08..e50f11c5165 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7294.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7294.json
@@ -1 +1 @@
-{"null": 1.359417735449565}
\ No newline at end of file
+{"AFINITOR": 14.985862645559529, "ALIMTA": 11.283119446394767, "CABOMETYX": 13.3523608934262, "EVEROLIMUS": 45.353502992322944, "FASLODEX": 20.49427772318037, "FULVESTRANT": 14.24136174074307, "IBRANCE": 4.226371579235717, "IRESSA": 29.596189572494023, "KEYTRUDA": 16.600211251913457, "MEKINIST": 9.119982180505314, "NEXAVAR": 7.209523246523186, "OPDIVO": 7.970671401605895, "SUTENT": 2.07387487602379, "TAGRISSO": 16.791500949232315, "null": 0.2389659760747344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7295.json
index beb21bfad8d..8fd7c52e365 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7295.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7295.json
@@ -1 +1 @@
-{"null": 3.1582598847212897}
\ No newline at end of file
+{"GEFITINIB": 2091.4869565741496, "OSIMERTINIB": 887.0728703677532, "null": 0.2603721666312293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7296.json
index 1a43fd13816..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7296.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7296.json
@@ -1 +1 @@
-{"IBUPROFEN": 33.850797699135974, "OPSUMIT": 15.83053765456224}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7297.json
index fc60445858c..247974da7a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7297.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7297.json
@@ -1 +1 @@
-{"BEDAQUILINE": 28.69246175133772, "DASATINIB": 115.5225267784365, "ENTRESTO": 9.651148461207525, "MEPOLIZUMAB": 11.446924330030573, "OPSUMIT": 28.88555525272328, "SILDENAFIL": 46.27767370872581, "TRACLEER": 19.92864815176336}
\ No newline at end of file
+{"ADCIRCA": 62.22821080783974, "CLOPIDOGREL": 10.854841464256872, "ELIQUIS": 4.416732449294473, "PEGINTRON": 5.054866311248769, "PLAVIX": 10.188390947509518, "SUTENT": 2.769755244233066, "null": 1.187698530408103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7298.json
index 3c816cc8a49..b93ac5ea9a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7298.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7298.json
@@ -1 +1 @@
-{"null": 1.5074906584087648}
\ No newline at end of file
+{"ABILIFY": 1.270575303565579, "ADALIMUMAB": 0.250279818403897, "AFINITOR": 1.6721068889744224, "AMINOSALICYLIC": 2.553992999526739, "ARANESP": 1.3471677479735225, "ARAVA": 0.2861469803934438, "ASPARAGINASE": 3.4388681663165293, "ATRIPLA": 0.1440979167039064, "AVASTIN": 1.819171725817763, "BUDESONIDE": 1.0803650357466292, "BUPRENORPHINE": 1.551875355021259, "BYETTA": 7.607901465940682, "CICLOSPORIN": 0.9296948767474688, "CIMZIA": 0.6259819862547249, "CLOPIDOGREL": 1.9455349872481649, "COMIRNATY": 0.0765914694065995, "CYMBALTA": 0.9759012029238852, "DEXAMETHASONE": 0.86097956759461, "ELIQUIS": 0.8384557111420962, "ENTYVIO": 3.180561977262026, "ESOMEPRAZOLE": 6.874981845884314, "EXJADE": 1.941364876810888, "FIRDAPSE": 11.32959981765502, "GARDASIL": 0.9074632575295122, "HUMALOG": 10.112903835487623, "HUMIRA": 3.104539215325586, "IBRANCE": 0.5325817218974607, "INLYTA": 1.7284998685634814, "INSULIN": 2.140396218281479, "JANUMET": 3.80702959301674, "JANUVIA": 6.5371979951144406, "KEYTRUDA": 1.1027156656066992, "LACOSAMIDE": 4.413136517393929, "LANTUS": 1.5764498651296297, "METHOTREXATE": 1.2656121054402492, "MIMPARA": 6.854318975706754, "NPLATE": 6.010383354639162, "OPSUMIT": 1.3451811003817251, "PEGASYS": 1.0345589417147654, "PEGINTRON": 2.100944198813491, "PLAVIX": 1.2821968964716284, "PRADAXA": 9.52112891603238, "RUBRACA": 4.121488334961979, "SOLIRIS": 1.2903625897197963, "SPIKEVAX": 0.0599102007437717, "SPINRAZA": 15.777376221445708, "STELARA": 1.6479839509210936, "STIVARGA": 1.726361786020384, "SUBOXONE": 0.9056884071230628, "SUTENT": 1.9434069373386136, "VOTRIENT": 1.3617120526091426, "XTANDI": 1.2656585040548949, "ZOSTAVAX": 1.127800253247035, "ZYPREXA": 1.854527958506844, "null": 0.9232830274996198}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7299.json
index a244e4b59ea..77541d89025 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7299.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7299.json
@@ -1 +1 @@
-{"ADCIRCA": 31.74211611495988, "ADEMPAS": 34.15061787427038, "AMBRISENTAN": 55.299270670161874, "AVANDIA": 1.4328827098640533, "BEDAQUILINE": 7.348301898010085, "BOSENTAN": 98.78318907556049, "BUSULFAN": 4.986543555337947, "DAPAGLIFLOZIN": 21.902004383062728, "ENTRESTO": 1.063683575487374, "IBUPROFEN": 2.7356591029030284, "MACITENTAN": 45.90248476607123, "OFEV": 4.051303740074024, "OPSUMIT": 87.0866361982028, "REVATIO": 30.143693775905938, "SILDENAFIL": 34.67934897692163, "SPRYCEL": 3.663126823974151, "TRACLEER": 136.42799760721908, "VIAGRA": 1.4283640668385136, "XARELTO": 3.661995248119708}
\ No newline at end of file
+{"null": 3.7064960077121447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/73.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/73.json
index acb2c77bbb3..56c73259e88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/73.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/73.json
@@ -1 +1 @@
-{"BIKTARVY": 60.87521138170389, "HUMALOG": 5.531772209135802, "LYRICA": 7.896435367570602, "MICARDIS": 53.41992311586037, "STELARA": 5.090528858433591, "SUBOXONE": 9.39313332671235, "VIAGRA": 26.149745521403563, "XELJANZ": 2.915284670566284, "null": 1.2759542744731365}
\ No newline at end of file
+{"STELARA": 71.92641011943233}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/730.json
index c0d9482d284..e07ddac7d6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/730.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/730.json
@@ -1 +1 @@
-{"ACLASTA": 3.9002260637323785, "ACLIDINIUM": 3.682160639153183, "ADCIRCA": 1.1690026769896602, "ADENURIC": 3.249946301836666, "ALENDRONATE": 13.453299975763764, "ALIMTA": 1.4997173001554789, "AMBRISENTAN": 1.232698601925953, "ANORO": 1.8422861573959903, "ANTIBIOTICS": 1.3251455678482715, "APIXABAN": 5.460043157999593, "AVANDAMET": 10.241911629514291, "AVANDIA": 10.33862560469207, "AXICABTAGENE": 1.9387648410953389, "AZACITIDINE": 1.1131418501550674, "AZILECT": 2.075501152781852, "BETMIGA": 8.62945311230828, "BLINDED": 7.3001707767261905, "BORTEZOMIB": 1.149650419459869, "BOSENTAN": 2.0038012078612417, "BOSULIF": 2.221035254214039, "BRIDION": 1.6435255687208172, "BRUKINSA": 3.573149110231776, "BUMETANIDE": 6.616978752788126, "BYDUREON": 1.5317643734684778, "BYETTA": 1.640782735321328, "CABAZITAXEL": 1.6103542067540988, "CARFILZOMIB": 1.6357258276103055, "CARMUSTINE": 1.163686965912743, "CASPOFUNGIN": 2.478584467151659, "CELECOXIB": 1.0424578712926933, "CHAMPIX": 1.037088512928986, "CHOLESTAGEL": 9.530977583864438, "CIALIS": 1.6244678420116647, "CLOPIDOGREL": 1.41452777352146, "DABIGATRAN": 4.931400790226213, "DAPAGLIFLOZIN": 1.4129858511153084, "DARATUMUMAB": 3.092356399071226, "DARBEPOETIN": 1.4263129588116814, "DARZALEX": 3.188454027293862, "DENOSUMAB": 1.2555979810103794, "DEXAMETHASONE": 1.243579786796743, "DOFETILIDE": 16.851594821294245, "DOXORUBICIN": 2.465668338671068, "DRONEDARONE": 10.078208180768632, "EDOXABAN": 8.93195446424499, "EFIENT": 2.0732537521342174, "ELIQUIS": 8.619192447603272, "EMEND": 1.4345242313074122, "EMPAGLIFLOZIN": 2.9328710162173706, "ENOXAPARIN": 1.2416510508623435, "ENTRESTO": 3.7706376588443553, "ENZALUTAMIDE": 1.5888499542149035, "ERLEADA": 1.363558806717054, "ESBRIET": 1.9102006733339636, "EUCREAS": 1.5787700515888954, "EVENITY": 2.734237611659318, "EVEROLIMUS": 1.078100414798591, "EVISTA": 1.8055917905426004, "EXFORGE": 1.2537857091794375, "EXVIERA": 1.373353694906025, "FEBUXOSTAT": 1.5688778263779817, "FIRDAPSE": 2.549596115594594, "FLEBOGAMMA": 1.193000691152142, "FORSTEO": 1.4299278765259242, "GALAFOLD": 2.555762416166219, "GAZYVARO": 1.1339147138135033, "GLIVEC": 1.1895642904178143, "HARVONI": 1.2184876308755983, "IBRUTINIB": 10.00764399171014, "ICLUSIG": 5.980738636145268, "IMATINIB": 1.080198313817179, "IMBRUVICA": 10.47502890723756, "INCRUSE": 2.9188989170534034, "INVOKANA": 1.230784336514257, "IRBESARTAN": 2.92151138269778, "IRON": 2.0970978593117104, "JANUVIA": 1.6385261983700323, "JARDIANCE": 1.2199413996704278, "JEVTANA": 1.471357834002212, "KISQALI": 1.2271592591471183, "KYPROLIS": 4.909313221028522, "LIXIANA": 1.8066484936357483, "MABTHERA": 1.7007377781281183, "MEMANTINE": 1.8860209108546853, "MICARDIS": 2.293629862795349, "MIRABEGRON": 2.1080446807391726, "MULTAQ": 42.74937789232369, "NILOTINIB": 2.66955785282084, "NO": 6.665321115464096, "NPLATE": 1.6991598481469077, "OPSUMIT": 1.900517287485097, "OZEMPIC": 3.946347968443265, "PACLITAXEL": 1.136470795075129, "PANTOPRAZOLE": 2.045341204475924, "PLAVIX": 2.1074601914480384, "POMALIDOMIDE": 3.8203628022725975, "PRADAXA": 5.063531688034881, "PROTELOS": 1.2220979750264012, "RASILEZ": 1.808224039060388, "REBETOL": 1.4436938935501218, "RELVAR": 2.089379859304194, "REMDESIVIR": 2.2062097818313853, "REVATIO": 1.751108736574888, "REVLIMID": 2.9234328772385787, "RITUXIMAB": 1.0159365289098248, "RIVAROXABAN": 3.5577553749959256, "ROSIGLITAZONE": 5.488415766008535, "SAXENDA": 1.146703757008462, "SILDENAFIL": 1.2576319775118696, "SITAGLIPTIN": 3.154185122295811, "SOVALDI": 1.3473821947270306, "SPIRONOLACTONE": 2.971471402157264, "SPRYCEL": 2.229927328934941, "SUGAMMADEX": 8.112470490368743, "TAGRISSO": 1.5838863552129012, "TASIGNA": 3.4710419111827298, "TERIPARATIDE": 1.846343984320489, "TESTOSTERONE": 2.0124080333086325, "TIKOSYN": 24.69335469179725, "TOVIAZ": 1.0132148402796075, "TRACLEER": 1.5617519484089857, "TRELEGY": 3.1702367924003254, "VALSARTAN": 2.922900005109394, "VEKLURY": 1.4975462975602012, "VELTASSA": 1.3723490251340371, "VENETOCLAX": 1.4305015540864976, "VIAGRA": 1.9343700392850736, "VICTOZA": 1.5160890475509794, "VIMPAT": 2.00903114727133, "XARELTO": 4.146959022064968, "XTANDI": 1.0782856825829836, "YESCARTA": 1.430805905615762, "ZELBORAF": 1.227214125924125, "ZOMETA": 1.0569149939281697, "ZOSTAVAX": 1.8668873588546813, "null": 1.2132165546227145}
\ No newline at end of file
+{"COMIRNATY": 0.5377687796506059, "DOXORUBICIN": 1003.0704904166596, "null": 0.2136833458298725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7300.json
index 56faec123b2..d511bd3f0b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7300.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7300.json
@@ -1 +1 @@
-{"ALENDRONATE": 1641.0702669251425, "APIXABAN": 31.15556726924348, "OPSUMIT": 7.783177629039145, "null": 2.250110311145208}
\ No newline at end of file
+{"null": 1.2888650102821348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7301.json
index b0fb9475eee..cd6a488d6b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7301.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7301.json
@@ -1 +1 @@
-{"OPSUMIT": 29.219766772787864}
\ No newline at end of file
+{"null": 1.0160645214141928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7302.json
index e75d5a55612..155d727890c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7302.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7302.json
@@ -1 +1 @@
-{"TRACLEER": 242.0200617494706}
\ No newline at end of file
+{"TRIUMEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7303.json
index c8d157a44aa..055048f41d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7303.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7303.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.0337425552645043, "ADVATE": 4.55197166552746, "AIMOVIG": 1.8902903644672275, "APIDRA": 2.490099813857005, "AUBAGIO": 1.2522362829233298, "BRIVIACT": 1.901497748227088, "BUPRENORPHINE": 4.476398343965341, "BYDUREON": 2.08191867192392, "BYETTA": 2.113078741334117, "CELECOXIB": 7.658578886873633, "CHAMPIX": 6.422506228763827, "COMTAN": 4.141294074063699, "COSENTYX": 1.1685250167575876, "CYMBALTA": 1.7437170750791129, "ELIQUIS": 1.5329512631463111, "EPIVIR": 3.20995362622218, "ESBRIET": 1.383847571538517, "EVENITY": 1.5148150669463556, "EVISTA": 2.626895400609443, "EXFORGE": 1.4017390903513127, "EXJADE": 1.1308746500518274, "FAMPYRA": 1.0161892047084526, "FENTANYL": 2.1382051666997635, "FORSTEO": 1.5166657732330706, "HARVONI": 1.3635490627306122, "HEMLIBRA": 3.418749076493913, "HUMALOG": 7.132725347175257, "HUMIRA": 1.6117028308468315, "INLYTA": 1.15105447458213, "INSULIN": 2.294145419942483, "JANUVIA": 1.915354290912917, "JARDIANCE": 1.2278548064386037, "KAFTRIO": 1.022955730633486, "KEPPRA": 2.13216943554359, "LANTUS": 4.270329993671052, "LATUDA": 2.295264592706149, "LEVEMIR": 3.0535359425482933, "LYRICA": 6.22930393514226, "MICARDIS": 2.2818473215865467, "NOVORAPID": 1.2324535407074315, "OMALIZUMAB": 1.7228037055758991, "OPSUMIT": 1.1656650570110718, "OZEMPIC": 4.889178390555089, "PEGASYS": 1.7561001104376732, "PEGINTERFERON": 1.092949216246618, "PEGINTRON": 1.6195764466039737, "PREGABALIN": 1.0372557279275527, "REMICADE": 1.6260098122873392, "REVATIO": 1.336359500239128, "RUCONEST": 3.083005395505062, "SAXENDA": 1.025669078556888, "SIFROL": 4.237886059468402, "SIMPONI": 1.5733834343658262, "SOVALDI": 1.4807323489323363, "SPINRAZA": 2.320446465359991, "STELARA": 1.7607826475277544, "SUBOXONE": 14.882866851881028, "TOVIAZ": 2.2744803416205794, "TRACLEER": 1.0817998684001429, "TRELEGY": 1.7325388760099607, "TREMFYA": 1.872797181402461, "TRESIBA": 2.666570865626205, "TRULICITY": 1.1258345726507746, "VIAGRA": 9.19918756923096, "XELJANZ": 2.4557194737462376, "XOLAIR": 1.7085517469880669, "XTANDI": 1.0212655735886045, "XYREM": 4.025683305634043, "ZOSTAVAX": 1.0272407090221298, "ZYPREXA": 1.7402885232875145, "null": 1.7228612234894705}
\ No newline at end of file
+{"ZOSTAVAX": 18.35736270518949, "null": 3.87751768576116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7304.json
index 64541bb817c..221554be92b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7304.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7304.json
@@ -1 +1 @@
-{"null": 1.3583110108629803}
\ No newline at end of file
+{"COSENTYX": 24.5840705636965, "JANUVIA": 32.371633368699, "null": 0.955199640121934}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7305.json
index 55bd0a29edd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7305.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7305.json
@@ -1 +1 @@
-{"HUMIRA": 251.5805299526095, "XELJANZ": 15.596516280448414}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7306.json
index c89d16a61e7..0a333d07d66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7306.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7306.json
@@ -1 +1 @@
-{"COSENTYX": 1.5236084228241376, "MIRABEGRON": 69.51356078794029, "MIRVASO": 711.5949721018367, "RINVOQ": 29.57627113436828, "XELJANZ": 3.603283907128744, "ZOSTAVAX": 8.802447006537854}
\ No newline at end of file
+{"null": 0.8839493325626656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7307.json
index 5acb1534083..498bf5fb91f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7307.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7307.json
@@ -1 +1 @@
-{"null": 4.066377393236062}
\ No newline at end of file
+{"ABILIFY": 11.539308753896876, "ARIPIPRAZOLE": 9.611641253537051, "ATRIPLA": 0.0644977119991406, "BRINTELLIX": 7.674561732956182, "CHAMPIX": 7.747715824987102, "COMIRNATY": 0.0170781618492084, "CYMBALTA": 5.413414935247688, "DEXAMETHASONE": 0.9824059003170214, "DULOXETINE": 3.2656066291112675, "IBUPROFEN": 0.5423147693627448, "INTRONA": 6.337118613283159, "KAFTRIO": 1.9636589759644456, "KEPPRA": 1.571840675250066, "LATUDA": 36.81915325790826, "LEVETIRACETAM": 2.0401322781360087, "LEVOFLOXACIN": 0.5057553156614062, "LURASIDONE": 26.33287787536992, "LYRICA": 1.117621929128326, "OLANZAPINE": 10.67060763158964, "PANTOPRAZOLE": 1.3666142137825148, "PEGASYS": 1.6772593062429324, "PEGINTERFERON": 1.210793268492226, "PEGINTRON": 2.4160397795734907, "RIBAVIRIN": 2.823502289625839, "RISPERIDONE": 8.287095506684738, "SIFROL": 5.120873990572349, "SPIKEVAX": 0.0396289785172766, "SUBOXONE": 1.0334214478245751, "SYCREST": 13.290526507603497, "TAMIFLU": 1.2244596719034446, "TOZINAMERAN": 0.0967160739805822, "VARENICLINE": 16.873937286848534, "VAXZEVRIA": 0.0476088208361568, "VFEND": 1.6682581432835737, "VIMPAT": 1.981299094672912, "VORICONAZOLE": 2.045216658957756, "XYREM": 3.17662604767393, "ZONISAMIDE": 14.720482474685856, "ZYPADHERA": 1.785027744810754, "ZYPREXA": 9.842347318232331, "null": 3.565019790150239}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7308.json
index fd0ca9847b1..c12d274b236 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7308.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7308.json
@@ -1 +1 @@
-{"BYETTA": 13.606263001410984, "JANUMET": 12.671764333352703, "LANTUS": 6.822033855851455, "METHOTREXATE": 89.00792356516351, "XELJANZ": 7.315733578436119, "ZOSTAVAX": 5.462180156962764}
\ No newline at end of file
+{"null": 1.308269228709178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7309.json
index 702d9e724a7..6326baf6364 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7309.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7309.json
@@ -1 +1 @@
-{"BYETTA": 2.704555257417912, "CYMBALTA": 7.0658430004860495, "DEXAMETHASONE": 1.1013742430367466, "DULOXETINE": 3.55087542975524, "ENBREL": 2.221969481743316, "FLUTICASONE": 8.146768859504208, "HUMALOG": 2.913511354310729, "HUMIRA": 2.549712236589772, "LANTUS": 2.372459925156543, "LEVOFLOXACIN": 6.561657491677472, "MIRABEGRON": 25.548840965612587, "OPSUMIT": 1.0052262113043473, "SUBOXONE": 1.2711764704812525, "VIAGRA": 3.1146242617501745, "XELJANZ": 3.5603245042153384, "ZOSTAVAX": 7.642729290842138, "null": 1.7874388980204274}
\ No newline at end of file
+{"CYTARABINE": 31.931146453856304, "RITUXIMAB": 29.859327270456756, "TORISEL": 140.79980342004131, "VENETOCLAX": 81.83991858205871, "null": 0.2128717696834265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/731.json
index fbd4ec8fc0a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/731.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/731.json
@@ -1 +1 @@
-{"APIXABAN": 1.226753464862336, "AVANDAMET": 11.752151480888234, "AVANDIA": 13.00861855186044, "BLINDED": 132.11433638144547, "BUSULFAN": 7.240047845761822, "COMBIVIR": 3.15522514227467, "DARZALEX": 4.740390194507171, "DASATINIB": 14.029232324717643, "DEXAMETHASONE": 1.1485238986007271, "ELIQUIS": 3.943571338935379, "ENTRESTO": 3.9373078428742767, "ESBRIET": 1.8672157284950095, "IBUPROFEN": 1.1528527681091791, "LOPINAVIR": 11.802625291371566, "MULTAQ": 27.74035632452737, "OPDIVO": 1.3140978986309606, "OPSUMIT": 6.172755912901156, "PANTOPRAZOLE": 2.286983998935986, "PRADAXA": 9.031644623877863, "REVATIO": 2.5521778269132214, "RITUXIMAB": 1.8064436291953696, "TRACLEER": 5.94304999987833, "VFEND": 1.5706946648013498, "VIAGRA": 1.6122863007452044, "VIMPAT": 3.4506883187713835, "ZOSTAVAX": 2.0277423471486986, "null": 1.1503040195015313}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7310.json
index 7f8e89717d4..7462e69ef8f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7310.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7310.json
@@ -1 +1 @@
-{"ROTARIX": 278.5709048829182, "ROTATEQ": 1864.961970002797, "SYNAGIS": 18.476268971275363}
\ No newline at end of file
+{"ACALABRUTINIB": 4869.774588526102, "CAELYX": 129.70878503950638, "CARMUSTINE": 533.6099424136872, "CYTARABINE": 86.48253246507716, "IBRUTINIB": 455.5528273194338, "RITUXIMAB": 27.38585046319454}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7311.json
index b934c698616..39ccd412ae1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7311.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7311.json
@@ -1 +1 @@
-{"ROTATEQ": 10751.495924523562}
\ No newline at end of file
+{"REVLIMID": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7312.json
index 19209b5633b..c6945765257 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7312.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7312.json
@@ -1 +1 @@
-{"ABILIFY": 10.028048987094346, "AIMOVIG": 57.283429019661945, "OMALIZUMAB": 67.94600535346616, "STELARA": 10.489393430444723, "XOLAIR": 7.043352307243448}
\ No newline at end of file
+{"null": 4.084932439899535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7313.json
index 526ebb59ec5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7313.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7313.json
@@ -1 +1 @@
-{"MMRVAXPRO": 40.41853472716425, "null": 3.3960287103709885}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7314.json
index a28a65eed96..4a1d16b18c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7314.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7314.json
@@ -1 +1 @@
-{"MMRVAXPRO": 90.74842407454018, "null": 5.9756089375334325}
\ No newline at end of file
+{"null": 2.816159535938442}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7315.json
index 03b778baaf1..4f7cb8d6fae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7315.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7315.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7316.json
index ed87f262637..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7316.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7316.json
@@ -1 +1 @@
-{"TOZINAMERAN": 1.1735596005954836}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7317.json
index 37dcf8949d3..1e946624cc9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7317.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7317.json
@@ -1 +1 @@
-{"null": 1.7241948535250735}
\ No newline at end of file
+{"COMIRNATY": 0.5012480358340671, "EVENITY": 87.59384467418964, "FORXIGA": 15.423142331090466, "MIRCERA": 233.95195806552343, "SIMPONI": 7.2458069357004415, "null": 0.8112309016622591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7318.json
index 259c33436c4..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7318.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7318.json
@@ -1 +1 @@
-{"ENBREL": 70.36027789015519}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7319.json
index c10bdf76a30..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7319.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7319.json
@@ -1 +1 @@
-{"COMIRNATY": 2.6320423619467888, "COVID19": 1.8893452723896067, "VAXZEVRIA": 5.869045099237156}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/732.json
index 5c54809b054..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/732.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/732.json
@@ -1 +1 @@
-{"null": 2.59950973928883}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7320.json
index 40372a659ac..d28f3656163 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7320.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7320.json
@@ -1 +1 @@
-{"COMIRNATY": 10.37341959112922, "SPIKEVAX": 2.1231405514654367, "VAXZEVRIA": 4.4332254516051215}
\ No newline at end of file
+{"null": 4.676747362804496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7321.json
index 1425c7bb7a3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7321.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7321.json
@@ -1 +1 @@
-{"COMIRNATY": 3.4412560137489514, "PRIVIGEN": 33.18082922987183, "TOZINAMERAN": 1.5674935643652217, "VAXZEVRIA": 1.7688089965118157}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7322.json
index a08db2f248e..fa2c0fd6a94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7322.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7322.json
@@ -1 +1 @@
-{"COMIRNATY": 1.336790910071095, "COVID19": 3.259277327040506, "ENTRESTO": 27.96750828522805, "SPIKEVAX": 2.6901574532595385, "VAXZEVRIA": 1.651524253573445}
\ No newline at end of file
+{"RITUXIMAB": 323.5584399177592}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7323.json
index 57b2e275fd5..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7323.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7323.json
@@ -1 +1 @@
-{"CIMZIA": 5.488150365774672, "COMIRNATY": 3.2521150262284872, "FASENRA": 13.338254109417225, "KEPPRA": 2.533607588762712, "SPIKEVAX": 1.4589813167937955, "TAGRISSO": 12.007149456124772, "VAXZEVRIA": 5.015705715630027}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7324.json
index bc0e1fa8a03..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7324.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7324.json
@@ -1 +1 @@
-{"ACTRAPID": 6.7637408373775605, "ARIPIPRAZOLE": 5.055686036140761, "AUBAGIO": 2.7405188461138046, "BENLYSTA": 1.123235290088684, "CIMZIA": 1.405476611780586, "COMIRNATY": 4.549785725458658, "FASENRA": 1.6403743508867126, "HIZENTRA": 1.084456797256267, "HUMIRA": 1.3615127290174904, "ICLUSIG": 2.3584602267752177, "JCOVDEN": 26.0661657894208, "KAFTRIO": 3.046375783943583, "KESIMPTA": 5.556937183258048, "LEMTRADA": 1.798579567801311, "METFORMIN": 3.699339718112823, "NUCALA": 1.1569780324881822, "PANTOPRAZOLE": 1.19145233961555, "PLEGRIDY": 2.346664966158821, "RINVOQ": 1.2880963861433743, "RITUXIMAB": 1.6640874715895864, "ROACTEMRA": 1.2263667464887256, "SEMAGLUTIDE": 12.460136442818133, "SOLIRIS": 4.838366183420367, "SPIKEVAX": 2.915732353420042, "SPINRAZA": 4.789618612811015, "STELARA": 1.3526482897336345, "SYNAGIS": 1.6186155744305106, "TELMISARTAN": 3.7698750474433584, "TOZINAMERAN": 2.1600787663012286, "TREMFYA": 2.4737381089235084, "VAXZEVRIA": 4.204660628264038, "VEKLURY": 15.97268192033812}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7325.json
index 21aee758fb0..9ea5654d8be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7325.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7325.json
@@ -1 +1 @@
-{"null": 1.3072808816042267}
\ No newline at end of file
+{"null": 3.748107862805465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7326.json
index 1d13a21dc06..98786c845da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7326.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7326.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 129.12502074221308, "BELIMUMAB": 2302.5150139179664, "BENLYSTA": 53.664008332320535}
\ No newline at end of file
+{"AZATHIOPRINE": 32.88349801891645, "BUSULFAN": 17.46706755226175, "CICLOSPORIN": 5.828953385832655, "EXJADE": 13.520492208506973, "NPLATE": 37.25801268760016, "null": 0.8201236476872061}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7327.json
index eda71a2d484..1476c1d8e2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7327.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7327.json
@@ -1 +1 @@
-{"null": 1.0184682174631474}
\ No newline at end of file
+{"ABACAVIR": 1.2050350196378266, "AFINITOR": 2.6790957090526226, "ARAVA": 0.6743953574047804, "BUDESONIDE": 0.5418113580356235, "BYDUREON": 2.3358655038620197, "CAPECITABINE": 1.7732112931333417, "CICLOSPORIN": 2.5149570793364564, "CIMZIA": 0.8165842301438541, "COMIRNATY": 0.4957766883397277, "COSENTYX": 1.170416184952135, "CYMBALTA": 0.3736466020658489, "ELIQUIS": 0.7907498056731465, "ENBREL": 0.6658748104096801, "FASLODEX": 3.613092717923352, "FENTANYL": 0.5762533377082782, "FORSTEO": 2.3331873544068142, "GARDASIL": 0.9603525526915896, "HERCEPTIN": 2.654234136363378, "HUMALOG": 0.7559692152435643, "HUMIRA": 1.0850877201605529, "IBRANCE": 0.8426814351512681, "JAKAVI": 1.4110771501641564, "KEYTRUDA": 0.8212353534745496, "LANTUS": 0.4553072247454977, "MEKINIST": 1.1815960518410171, "METHOTREXATE": 1.8140714614924769, "NEXAVAR": 0.4876104636576357, "OPTIMARK": 120.83878278883608, "PEGASYS": 2.1574938055007142, "PEGINTRON": 0.955806555815532, "PLAVIX": 0.8968185876000994, "REMICADE": 3.500942397417381, "ROACTEMRA": 1.1106004650408936, "SIMPONI": 2.822972695648324, "SOLIRIS": 0.8493458412061303, "SPIKEVAX": 0.5045757291399298, "STELARA": 1.6024454629369067, "SUTENT": 1.0799010031994198, "TOZINAMERAN": 1.7509273430643648, "TRULICITY": 1.4132988241670592, "VAXZEVRIA": 0.3640585109839885, "XELJANZ": 1.2252031025787316, "XOLAIR": 1.4965853856184594, "XTANDI": 1.651045562280472, "ZELBORAF": 21.7387670768274, "ZOSTAVAX": 1.5213570173951545, "ZYPREXA": 0.4382144442669254, "null": 0.6116857416101693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7328.json
index ab2e5a5c967..46b77d9841d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7328.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7328.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3271646062149445, "COSENTYX": 5.821039060833801, "FORSTEO": 4.455969636610332, "IBUPROFEN": 9.559130714319048, "SUTENT": 1.9598210384150705, "VAXZEVRIA": 2.388434177670164}
\ No newline at end of file
+{"ENBREL": 21.853021160873944, "null": 0.7753087338246478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7329.json
index ee4b4304f7c..46fa7bfa856 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7329.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7329.json
@@ -1 +1 @@
-{"COMIRNATY": 2.5861358106910566}
\ No newline at end of file
+{"CELECOXIB": 18.30157064051844, "COMIRNATY": 2.4202833779681745, "GARDASIL": 19.37366384462523, "OMALIZUMAB": 7.426339932602821, "SPIKEVAX": 1.088572431670282, "TOZINAMERAN": 2.9834674200484845, "VAXZEVRIA": 0.6598640024901237, "XOLAIR": 8.266462843097395, "null": 0.3244478911898163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/733.json
index 1ffebc51a08..682ae0405d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/733.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/733.json
@@ -1 +1 @@
-{"null": 1.359417735449565}
\ No newline at end of file
+{"ABATACEPT": 64.23401385262568, "ADALIMUMAB": 115.09583495639583, "APREPITANT": 18.884061263319705, "ARAVA": 2.7535716367113023, "AVAMYS": 23.558599190101067, "CIMZIA": 4.463552164771494, "HUMIRA": 11.589286023490637}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7330.json
index f61f257a3f0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7330.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7330.json
@@ -1 +1 @@
-{"ADALIMUMAB": 6.4446554417178525, "ANAKINRA": 41.80354409344876, "CIMZIA": 7.847750960247351, "COSENTYX": 19.029228100966705, "ENBREL": 12.548333304250576, "ENTYVIO": 7.678206294414727, "GARDASIL": 4.098291570171042, "HUMIRA": 14.500019471821634, "NEVANAC": 122.89683715850722, "SIMPONI": 4.213360950886609, "STELARA": 9.368177883226736}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7331.json
index 35890731141..b902c6a3e7e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7331.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7331.json
@@ -1 +1 @@
-{"PEGASYS": 2.2615832925699286, "null": 1.5780551308446642}
\ No newline at end of file
+{"DOCETAXEL": 9.740352953705187, "IBRANCE": 11.271158667568884, "JANUMET": 14.564644877862738, "JANUVIA": 12.177316021787306, "KEYTRUDA": 3.403520599257982, "XOLAIR": 4.165933766731786, "null": 2.0385966167695466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7332.json
index 1482483133d..84e9e6a80c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7332.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7332.json
@@ -1 +1 @@
-{"null": 1.4863998810893884}
\ No newline at end of file
+{"ABILIFY": 5.237408506474144, "ATRIPLA": 1.0748474622677675, "BUPRENORPHINE": 5.768495776191381, "COMIRNATY": 0.5706644183251811, "GARDASIL": 1.59361747050843, "LEVETIRACETAM": 4.160746158167752, "SPIKEVAX": 0.5062956178398591, "SUTENT": 5.709146577531008, "TOZINAMERAN": 1.552176625763997, "VAXZEVRIA": 0.4054304336314868, "null": 1.0797629469969297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7333.json
index 9cbad01d2ad..f0401afe8dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7333.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7333.json
@@ -1 +1 @@
-{"null": 1.0575416466027538}
\ No newline at end of file
+{"null": 0.5234282361212452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7334.json
index 02a6b076d2a..062b9c2b8a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7334.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7334.json
@@ -1 +1 @@
-{"null": 1.1419080644232673}
\ No newline at end of file
+{"COMIRNATY": 2.738962624326126, "IBRANCE": 4.794771848829444, "MODERNA": 2.5129546396498954, "SPIKEVAX": 1.037282719628544, "STELARA": 2.271776736105846, "TOZINAMERAN": 4.247330023829098, "VAXZEVRIA": 0.5503966853032155, "XELJANZ": 1.9739135076613088, "null": 0.4571435498375569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7335.json
index 03b6b0830bc..cf3027bb61f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7335.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7335.json
@@ -1 +1 @@
-{"null": 1.499467059653714}
\ No newline at end of file
+{"COMIRNATY": 10.95270334788807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7336.json
index 6e3e5c1cfb6..28c9315c5fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7336.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7336.json
@@ -1 +1 @@
-{"MMRVAXPRO": 4.84422517230094, "null": 3.7943728185512704}
\ No newline at end of file
+{"CLOPIDOGREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7337.json
index 5631dc1fbe7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7337.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7337.json
@@ -1 +1 @@
-{"null": 5.039246345822313}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7338.json
index 2e4747bbc65..699df8482bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7338.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7338.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1682396440637863, "MMRVAXPRO": 12.110602093909923, "null": 1.5904527458832514}
\ No newline at end of file
+{"COMIRNATY": 0.2586834043851966, "OMALIZUMAB": 24.91916317246141, "null": 0.7408014676776732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7339.json
index 4f24da400fe..9ac9b7ee6fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7339.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7339.json
@@ -1 +1 @@
-{"ABILIFY": 4.663403950523844, "ARIPIPRAZOLE": 12.638884327685249, "BRINTELLIX": 5.358264333240608, "BRIVARACETAM": 9.206596484649689, "FYCOMPA": 4.646227622764214, "INFANRIX": 5.1017441654748, "INVEGA": 18.883259056039243, "KEPPRA": 1.928018581213176, "LATUDA": 6.851420571599473, "LEVETIRACETAM": 1.80433127231777, "MIDAZOLAM": 2.9668558410389174, "MMRVAXPRO": 1.885128726445211, "NIMENRIX": 1.429212407402633, "OLANZAPINE": 11.735021841450695, "REAGILA": 21.94485867325364, "RISPERIDONE": 30.957771260479024, "SPINRAZA": 5.2650368230409965, "STALEVO": 5.172281028187067, "SYCREST": 9.417935945721217, "ZYPADHERA": 4.118029418083848, "ZYPREXA": 4.97840556391158, "null": 2.8299942871306256}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/734.json
index e71161030d9..007a397cb70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/734.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/734.json
@@ -1 +1 @@
-{"ASPARAGINASE": 5.094021886965418, "BUPRENORPHINE": 1.037128316969269, "COMBIVIR": 10.796677835076316, "EMTRICITABINE": 20.260540210180885, "EPIVIR": 7.336026015714461, "IBUPROFEN": 3.871928387731611, "KALETRA": 3.098005466921921, "KEPPRA": 4.035505845829315, "LEVETIRACETAM": 3.719095114159988, "LYRICA": 1.1338710203546538, "MEPOLIZUMAB": 2.81266688987522, "MYCOPHENOLATE": 2.9144085509852693, "OPSUMIT": 1.3462666755443813, "SOVALDI": 6.304609474381127, "SYNAGIS": 2.501706363876992, "TRACTOCILE": 85.01316955297854, "ZYPREXA": 1.3435238083081176, "null": 6.294432837684384}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7340.json
index ff32cfb2187..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7340.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7340.json
@@ -1 +1 @@
-{"KEYTRUDA": 4.113975646860011, "SUTENT": 1.734474802625404, "null": 1.7606308115622522}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7341.json
index 137a910ff8a..8ddd36c247b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7341.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7341.json
@@ -1 +1 @@
-{"CICLOSPORIN": 6.850307006267866, "PEGASYS": 4.93995077456119, "ROTATEQ": 21.529745053860704}
\ No newline at end of file
+{"KAFTRIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7342.json
index 77e2ce57569..f9ac4e83904 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7342.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7342.json
@@ -1 +1 @@
-{"CYMBALTA": 56.50052127117235}
\ No newline at end of file
+{"TEZACAFTOR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7343.json
index e958fe0e970..90eef23deff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7343.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7343.json
@@ -1 +1 @@
-{"BUDESONIDE": 142.27412353519566}
\ No newline at end of file
+{"ENOXAPARIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7344.json
index ad5fe62c046..f4f69068859 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7344.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7344.json
@@ -1 +1 @@
-{"HUMIRA": 252.3229399113025}
\ No newline at end of file
+{"ISENTRESS": 91.26929359263696, "null": 5.448564982694447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7345.json
index 413385beb2a..dfeee28440a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7345.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7345.json
@@ -1 +1 @@
-{"ACLIDINIUM": 92.18287781947332, "ALEMTUZUMAB": 3.3277434525972134, "ANORO": 5.201127295567908, "ARAVA": 1.196091360365208, "AUBAGIO": 1.896842919475188, "AVAMYS": 8.412933791849955, "CELLCEPT": 1.305385497065083, "CIMZIA": 2.447485610845775, "COSENTYX": 1.6155478001870518, "COTELLIC": 8.190375012864958, "DABRAFENIB": 11.07554627931574, "HUMALOG": 1.0274233184221129, "INCIVO": 4.3545107438653625, "INTRONA": 10.236303744746046, "IPILIMUMAB": 10.22796560870914, "KEYTRUDA": 4.18336099069734, "LANTUS": 1.051445710771124, "MEKINIST": 6.378226086359593, "MEPOLIZUMAB": 3.1972066583225103, "METHOTREXATE": 2.5206733875574825, "OPDIVO": 3.400919556746724, "PEGASYS": 14.46405046873486, "PEGINTERFERON": 38.58698353506783, "PEGINTRON": 14.531881927398729, "PEMBROLIZUMAB": 8.471164720858777, "REBETOL": 16.87702577164137, "RIBAVIRIN": 35.234136354622734, "ROACTEMRA": 1.7304417276633246, "SIMPONI": 5.997387746254527, "STELARA": 4.055611918109393, "TRACLEER": 2.1001413990118114, "XOLAIR": 1.6111952133595844}
\ No newline at end of file
+{"ABACAVIR": 6.627569793842597, "ADALIMUMAB": 1.0478450198726452, "AIMOVIG": 1.2332271131209445, "ARAVA": 2.7943649284572616, "BRIVARACETAM": 55.54997841708654, "BRIVIACT": 46.264772324014366, "CIMZIA": 55.72949676224931, "COMIRNATY": 0.4066646035719431, "DUPILUMAB": 155.54580913172757, "ESMYA": 27.08950782560163, "GARDASIL": 5.572073221524352, "INSULIN": 3.5295077731290694, "KEPPRA": 14.028020401983577, "LACOSAMIDE": 8.317683615015683, "LEVETIRACETAM": 8.056050921382376, "MAVENCLAD": 35.08613985340896, "MMRVAXPRO": 11.285844510184155, "SPIKEVAX": 0.1055165766017545, "TOZINAMERAN": 0.8236080669313198, "VAXZEVRIA": 0.0881836386799553, "VIMPAT": 23.43509053558697, "null": 0.464654648972556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7346.json
index ce2763db66e..de0f1be69cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7346.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7346.json
@@ -1 +1 @@
-{"CICLOSPORIN": 4.945154177224769, "SUTENT": 1.8976731011209536, "VOTRIENT": 77.62989729937053, "YONDELIS": 123.17448561593534}
\ No newline at end of file
+{"AZATHIOPRINE": 2.9648097360691885, "BRIVARACETAM": 31.63918674749975, "BUPIVACAINE": 10.320405116655442, "CIMZIA": 13.10703964498834, "COMIRNATY": 0.7243855392837777, "DULOXETINE": 1.746370653794708, "ENTYVIO": 2.113762683026138, "HUMALOG": 1.8323695078938576, "HYDROCORTISONE": 6.615894698342533, "IBUPROFEN": 0.8058572188730504, "KEPPRA": 4.96769277905448, "KESIMPTA": 4.468809395352782, "RUCONEST": 16.68983578534393, "SOLIRIS": 2.5023135859666623, "SPIKEVAX": 2.5705593562706834, "SUBOXONE": 1.7162227558193095, "TOZINAMERAN": 2.0697984339959827, "VAXZEVRIA": 6.020379096493335, "VIMPAT": 3.756021888934713, "null": 0.362970673666791}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7347.json
index 166c0f6344e..dbd89b73d73 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7347.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7347.json
@@ -1 +1 @@
-{"VOTRIENT": 281.6086071350395}
\ No newline at end of file
+{"BRIDION": 11.925797637085072, "BUPIVACAINE": 113.31094354159303, "FENTANYL": 34.589107573576335, "SUFENTANIL": 66.73311128693486, "null": 7.151954875360145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7348.json
index 3eacc2ab720..a0fafcb7d1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7348.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7348.json
@@ -1 +1 @@
-{"ESMYA": 887.0831012578955, "null": 1.0184682174631474}
\ No newline at end of file
+{"ABACAVIR": 3.212953764124815, "ABASAGLAR": 1.0144146924856878, "ABATACEPT": 4.0269430278235046, "ABILIFY": 3.871931466317655, "ACTRAPID": 1.76778488748224, "ADALIMUMAB": 6.089418813686689, "AERIUS": 1.7219978908357514, "AIMOVIG": 1.4473859910354052, "ALECTINIB": 9.549310742223993, "ALISKIREN": 1.405040827763956, "AMIKACIN": 0.381932926098222, "AMINOSALICYLIC": 0.3789185733135411, "ANAKINRA": 0.2453118868216337, "ANTIBIOTICS": 3.256675899068878, "APIDRA": 0.1950024489583895, "APREMILAST": 2.6306432381254594, "APREPITANT": 0.5337558704838481, "APROVEL": 0.48589591928678, "ARANESP": 0.2732495549900579, "ARAVA": 10.60478319495532, "ARIPIPRAZOLE": 2.1916406787784988, "ASPARAGINASE": 0.4109682260065738, "ATAZANAVIR": 4.276272077788864, "ATOSIBAN": 68.47129950844143, "ATRIPLA": 0.086894289154062, "AUBAGIO": 0.122242511840895, "AZATHIOPRINE": 5.600644107249742, "BARACLUDE": 3.500331343764132, "BEDAQUILINE": 0.7592505878036095, "BENZODIAZEPINE": 1.2201368828039705, "BETAFERON": 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2.0996718561273644, "TRULICITY": 0.1887164498246475, "TRUVADA": 0.2253210856627352, "VAXZEVRIA": 0.1386695816067199, "VEKLURY": 4.383736214846086, "VEMLIDY": 2.955896832124799, "VIGABATRIN": 3.5638714753386647, "VIMPAT": 6.051934033251827, "VIREAD": 1.6931467942198877, "XELJANZ": 0.1069202408491962, "XOLAIR": 3.8061345723664624, "ZYPREXA": 0.1438944676946823, "null": 0.8030131992495194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7349.json
index 8476c522724..9bae3d3ac07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7349.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7349.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 30.476718574151896}
\ No newline at end of file
+{"ADALIMUMAB": 3.9712551802630474, "APIDRA": 2.69748232895517, "AZATHIOPRINE": 19.045825555742734, "COMBIVIR": 27.75796375603813, "COMIRNATY": 1.1361470432701797, "COSENTYX": 5.555409159969018, "CRIXIVAN": 53.1598718254657, "EFAVIRENZ": 10.250307255066904, "FENTANYL": 8.416561639098669, "IBUPROFEN": 3.561150708794245, "ISENTRESS": 8.714920518361666, "LANTUS": 0.8079211955347013, "MAVENCLAD": 18.50955092292672, "METHOTREXATE": 5.698989428584896, "PEGASYS": 0.9960120635960008, "RITUXIMAB": 2.921425411671803, "TOZINAMERAN": 1.5902576073608692, "XOLAIR": 1.51890582295109, "null": 1.4799571731474472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/735.json
index 3c7c7ce1acf..7b777d1682d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/735.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/735.json
@@ -1 +1 @@
-{"OPSUMIT": 75.08161798233901, "TRACLEER": 144.42100034513936}
\ No newline at end of file
+{"ARANESP": 164.6642283935017, "PRIVIGEN": 319.4621010732637}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7350.json
index ef3268d467b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7350.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7350.json
@@ -1 +1 @@
-{"ALDARA": 66.07394693788449, "BENLYSTA": 1.473429413872104, "BUPIVACAINE": 3.5199129679088426, "CICLOSPORIN": 1.1568848824416549, "COSENTYX": 3.095811686173851, "HUMIRA": 1.035119858645368, "HYDROCORTISONE": 5.425677990819779, "IMIQUIMOD": 109.0103218570603, "KEYTRUDA": 1.03334694094889, "METHOTREXATE": 2.7699426964015026, "OPTIMARK": 3.652320539124522, "PEGASYS": 1.0365193586156145, "PEGINTRON": 1.061371450501066, "RENVELA": 284.79312495783785, "RINVOQ": 2.038828821780289, "SHINGRIX": 5.896810379119218, "STIVARGA": 1.533328352997381, "SUTENT": 1.5046332256577368, "ZOSTAVAX": 3.5522107429754106, "ZYCLARA": 135.80833631003176, "null": 3.151428518472483}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7351.json
index 6da6e667bec..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7351.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7351.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7352.json
index 94096e97d71..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7352.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7352.json
@@ -1 +1 @@
-{"ENTRESTO": 363.8191432832047}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7353.json
index b1aed4df1aa..c079965f928 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7353.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7353.json
@@ -1 +1 @@
-{"SPIKEVAX": 13.10763368182544}
\ No newline at end of file
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7354.json
index 7b251531613..ca521850109 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7354.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7354.json
@@ -1 +1 @@
-{"null": 6.508249131985286}
\ No newline at end of file
+{"ACLIDINIUM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7355.json
index a1dab41b3c2..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7355.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7355.json
@@ -1 +1 @@
-{"ATRIPLA": 23.309734854504462}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7356.json
index 2a19f45df86..b130a01b8ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7356.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7356.json
@@ -1 +1 @@
-{"ALDARA": 8.408695199011598, "APIDRA": 1.4817926433263393, "ARAVA": 1.2456190323965768, "AVANDIA": 1.2839928576042907, "BENLYSTA": 1.3682238777134252, "BUPRENORPHINE": 1.14493903566635, "BYDUREON": 1.6864666906756485, "CONTRAST": 85.08085862769995, "COSENTYX": 2.3874912427344634, "CYMBALTA": 1.1340204920077954, "DEXAMETHASONE": 1.5022096006607284, "ENTYVIO": 1.955410753072024, "ERTAPENEM": 47.26430635587062, "HUMALOG": 2.944494538549733, "HUMIRA": 2.311254836593597, "LYRICA": 1.9205426760582691, "OPTIMARK": 103.21371493084332, "SHINGRIX": 4.1891411260517, "SUBOXONE": 1.3631654227688994, "VIAGRA": 1.7064616208124217, "VOTRIENT": 1.123072732971172, "ZOSTAVAX": 17.04068537786901, "null": 1.1137991090941042}
\ No newline at end of file
+{"AIMOVIG": 91.67807000145508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7357.json
index 6720c371930..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7357.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7357.json
@@ -1 +1 @@
-{"COMIRNATY": 6.927205357891813}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7358.json
index c6d7e32c52b..ebf9262850c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7358.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7358.json
@@ -1 +1 @@
-{"COMIRNATY": 2.359810902191282}
\ No newline at end of file
+{"FENTANYL": 40.51701647152327, "null": 2.1014083892596798}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7359.json
index 002df0821bd..2057f6f84f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7359.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7359.json
@@ -1 +1 @@
-{"CANNABIDIOL": 228.33166332942892, "COMIRNATY": 1.3146124055906196, "SPIKEVAX": 1.0005307377258044, "STELARA": 8.75053224659397}
\ No newline at end of file
+{"null": 0.7934161955149596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/736.json
index e78bdce14f9..e94e00ba1c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/736.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/736.json
@@ -1 +1 @@
-{"null": 1.4641793956652778}
\ No newline at end of file
+{"ARANESP": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7360.json
index 4ff4e6ce5a2..7ced2e8251d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7360.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7360.json
@@ -1 +1 @@
-{"null": 1.2402900514190265}
\ No newline at end of file
+{"ARIPIPRAZOLE": 11.68444987477716, "CICLOSPORIN": 3.4837459274819973, "COMIRNATY": 0.3524025588414934, "IBUPROFEN": 10.539002001634856, "JAKAVI": 17.357443163724362, "SUTENT": 2.1675762965384893, "TOZINAMERAN": 0.8687518639467239, "null": 0.5830591770084699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7361.json
index 9cbedb16c7f..e366e569cce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7361.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7361.json
@@ -1 +1 @@
-{"ANIDULAFUNGIN": 1236.0227957260513, "CASPOFUNGIN": 146.56999985542103, "CICLOSPORIN": 33.64824245304187, "CYTARABINE": 17.332703644595487, "TACROLIMUS": 118.72095024196096, "VORICONAZOLE": 79.74604688162609}
\ No newline at end of file
+{"COMIRNATY": 0.2800259359521177, "KYMRIAH": 63.47993213053206, "null": 0.3532826316928004}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7362.json
index af526f9f0b6..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7362.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7362.json
@@ -1 +1 @@
-{"MIDAZOLAM": 345.17629877803074}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7363.json
index 2ad17cdabb8..f6fdcd04855 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7363.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7363.json
@@ -1 +1 @@
-{"ABILIFY": 86.50235992561116, "ARIPIPRAZOLE": 398.5707204731624, "LATUDA": 19.77172888196404, "OLANZAPINE": 17.628727100045325, "ZYPREXA": 8.878148154916273}
\ No newline at end of file
+{"ABATACEPT": 12.67426175639904, "ADALIMUMAB": 6.810228408093049, "ALEMTUZUMAB": 43.40931262948704, "ARIPIPRAZOLE": 13.967259620590864, "CLOPIDOGREL": 6.652499718730822, "COMIRNATY": 0.1110201628122408, "LEMTRADA": 27.14992852047455, "XELJANZ": 2.6759222028009844, "null": 0.5598577718460522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7364.json
index 03edd8d035e..f8a0bb730b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7364.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7364.json
@@ -1 +1 @@
-{"ABILIFY": 47.54435432793934, "ACLIDINIUM": 68.72433453293026, "ANORO": 3.902714330724172, "APTIVUS": 116.30765672503898, "ARIPIPRAZOLE": 55.59312275978137, "BREXPIPRAZOLE": 192.80771390351524, "BUPRENORPHINE": 3.2067626358179955, "CHAMPIX": 4.4376329733018025, "EPADERM": 237.7034715968642, "INVEGA": 26.52068628790617, "IVABRADINE": 36.06121745877247, "LACOSAMIDE": 3.3964395526113127, "LATUDA": 37.88318525932536, "LURASIDONE": 57.35541437371493, "OLANZAPINE": 42.381292504494816, "PALIPERIDONE": 30.07224782992016, "PEGASYS": 1.5333474970827048, "PREGABALIN": 5.1039402573675785, "RISPERIDONE": 11.156527561526175, "SYCREST": 50.00330337169883, "TELMISARTAN": 6.0018915112044855, "XEPLION": 108.64342338680372, "ZYPADHERA": 21.36373084332392, "ZYPREXA": 17.08547428508869}
\ No newline at end of file
+{"ADENURIC": 64.76094136251939, "ARAVA": 6.954711107571752, "ARIPIPRAZOLE": 8.464716193731372, "COMIRNATY": 0.2346615593001726, "IBRANCE": 15.136296549090344, "KEYTRUDA": 3.238842142071366, "null": 0.354322191895107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7365.json
index 24c76fae825..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7365.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7365.json
@@ -1 +1 @@
-{"ABILIFY": 25.378071839638825, "CHAMPIX": 10.27620016105712, "ZYPREXA": 10.424357905123252, "null": 1.2754977174618285}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7366.json
index 7ccfd23fc67..24bd57e874d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7366.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7366.json
@@ -1 +1 @@
-{"GARDASIL": 37.88538870542823, "null": 2.7089287803149595}
\ No newline at end of file
+{"null": 0.6715044717395974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7367.json
index e77b6cbfe27..056dcfd8bb5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7367.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7367.json
@@ -1 +1 @@
-{"FASLODEX": 17.58374903252399, "LANTUS": 4.982175767001625, "null": 1.813935155996282}
\ No newline at end of file
+{"ABATACEPT": 15.17663317675065, "ADALIMUMAB": 5.876452180461031, "ARAVA": 0.8668264016689229, "ARIPIPRAZOLE": 8.817664404249829, "COMIRNATY": 0.1322409394710807, "ENBREL": 4.528331547241872, "JAKAVI": 14.90781545394081, "LEMTRADA": 16.241345340506424, "NUCALA": 6.053015161180841, "TOZINAMERAN": 0.5779102843448429, "null": 0.6191334819853107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7368.json
index 3430a9aeaf7..da8b538ea04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7368.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7368.json
@@ -1 +1 @@
-{"null": 1.3328806994464524}
\ No newline at end of file
+{"ADENURIC": 47.93895969587346, "ARAVA": 0.842011663957386, "BEVACIZUMAB": 12.514345031306783, "COMIRNATY": 0.1432190965651621, "EXJADE": 9.63950830565918, "IBRANCE": 19.303938368806342, "JAKAVI": 13.538031511884128, "LEMTRADA": 11.547690398123596, "PEGASYS": 1.8421951734116415, "PEGINTRON": 5.502575046946735, "SOLIRIS": 11.097166853296049, "SPIKEVAX": 0.1499239859750294, "SUTENT": 2.258030772482471, "null": 0.5860364234658378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7369.json
index 25bcff04d30..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7369.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7369.json
@@ -1 +1 @@
-{"null": 1.1733358945517447}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/737.json
index 178fb13a7e1..37f82ad1c4d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/737.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/737.json
@@ -1 +1 @@
-{"APIXABAN": 196.8941164544109, "AVANDIA": 1.8993627097841237, "CLOPIDOGREL": 1.3886854590412778, "ELIQUIS": 1.1716616294493536, "OPSUMIT": 2.2471425237514016, "null": 1.0372912690228853}
\ No newline at end of file
+{"PRIVIGEN": 729.7952524802394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7370.json
index b742d77d4a9..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7370.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7370.json
@@ -1 +1 @@
-{"ABATACEPT": 2.982553719062857, "ADALIMUMAB": 3.631989707946509, "AIMOVIG": 1.7436820985759374, "ANAKINRA": 2.452075853294096, "APIDRA": 1.1173288867297897, "APREMILAST": 6.610966849558594, "ARAVA": 2.775598812585476, "AUBAGIO": 3.407316723784616, "BUPRENORPHINE": 2.171464614485522, "BYDUREON": 1.96147458641132, "CELECOXIB": 2.841236451837871, "COSENTYX": 4.055659332945938, "ELIQUIS": 1.4188946291346725, "ENBREL": 2.131456938811206, "FASLODEX": 13.597141569898136, "FORSTEO": 5.432031300962419, "HARVONI": 2.650120604321654, "HUMALOG": 1.137175211803446, "IBRANCE": 1.6987992040071207, "INSULIN": 1.11062003477333, "JANUMET": 1.9326220191438663, "LANTUS": 1.6497041745309993, "LYRICA": 2.7674731205533214, "MEPOLIZUMAB": 1.8279663390727288, "METHOTREXATE": 1.0230881280837505, "PEGINTRON": 1.3041639753758307, "SHINGRIX": 1.391283364368189, "SIMPONI": 1.0312588286137316, "SPINRAZA": 2.935158369290608, "STELARA": 1.1911203770526044, "STRIBILD": 1.2105637499010438, "TASIGNA": 1.268574686419783, "TOZINAMERAN": 1.1708340598930351, "VIAGRA": 1.0570290892165457, "XELJANZ": 3.3862265188673946, "ZOSTAVAX": 6.052735617914976}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7371.json
index 2a9d2c920dd..a98572b3f1c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7371.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7371.json
@@ -1 +1 @@
-{"COMIRNATY": 1.13920011435291}
\ No newline at end of file
+{"ABATACEPT": 33.43629807720985, "ADALIMUMAB": 8.927588469904183, "CICLOSPORIN": 6.863738520972603, "COMIRNATY": 0.1633834963977543, "null": 0.2112424775808857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7372.json
index 7b9a914e041..4af1fbaee90 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7372.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7372.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"ENTRESTO": 43.03522717998387, "null": 0.3410678743161335}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7373.json
index 3eff6b685c0..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7373.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7373.json
@@ -1 +1 @@
-{"null": 3.058796406159473}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7374.json
index 11ec8b37c1a..3cbacef1745 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7374.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7374.json
@@ -1 +1 @@
-{"null": 2.290718289316207}
\ No newline at end of file
+{"COMIRNATY": 0.1027473085871704, "MMRVAXPRO": 43.75512412166614, "PREVENAR": 23.48731622613252, "TOZINAMERAN": 0.4388936391016369, "null": 6.394433373068468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7375.json
index 1c275066d1a..e6a68ba8f8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7375.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7375.json
@@ -1 +1 @@
-{"ELIQUIS": 12.977926372590542}
\ No newline at end of file
+{"MMRVAXPRO": 138.13164024857514, "null": 2.7886102062597917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7376.json
index a82da305eb5..18af6295247 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7376.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7376.json
@@ -1 +1 @@
-{"null": 1.8947203928902423}
\ No newline at end of file
+{"PROQUAD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7377.json
index e3b58f37116..646b159af7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7377.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7377.json
@@ -1 +1 @@
-{"null": 3.390987587429732}
\ No newline at end of file
+{"MMRVAXPRO": 137.43701108319576, "null": 5.082210898913655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7378.json
index 18340aaac57..2ae0328edb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7378.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7378.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 224.95115979740183, "null": 1.9541065989600708}
\ No newline at end of file
+{"null": 1.0252078270834757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7379.json
index 9cbad01d2ad..6dc58abfe75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7379.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7379.json
@@ -1 +1 @@
-{"null": 1.0575416466027538}
\ No newline at end of file
+{"COMIRNATY": 1.2096309229285322, "GARDASIL": 1.9776454014107756, "MODERNA": 6.741333063009982, "OMALIZUMAB": 4.674432427142381, "SPIKEVAX": 9.001892321218055, "TOZINAMERAN": 0.7427422996290707, "VAXZEVRIA": 0.2889546235970385, "null": 0.5214343242902282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/738.json
index 1de4d771a8f..832f01a44ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/738.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/738.json
@@ -1 +1 @@
-{"APIXABAN": 11.374088001647412, "BUSULFAN": 7.890785400445456, "CLOPIDOGREL": 3.0775439563132663, "ELIQUIS": 74.41860959711089, "LIXIANA": 51.04701895647843, "MISOPROSTOL": 220.9642656207368, "NOVOSEVEN": 54.12663883398388}
\ No newline at end of file
+{"ARANESP": 63.481927141659774, "null": 2.889743278386645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7380.json
index 9efbed928d1..c04da18b5cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7380.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7380.json
@@ -1 +1 @@
-{"EYLEA": 14.617897733175546, "SIMPONI": 7.208102999170163}
\ No newline at end of file
+{"ARAVA": 0.2829385381795192, "BIKTARVY": 5.804577235091415, "BRIDION": 22.862618559067197, "CICLOSPORIN": 10.708056199764467, "COMIRNATY": 0.0326786146314405, "CUBICIN": 9.780774841754138, "FENTANYL": 3.6308357845251287, "KALETRA": 15.431316946353672, "KEPPRA": 1.988667243240582, "OPSUMIT": 2.3497335354805418, "SPIKEVAX": 0.474993553884855, "TRACLEER": 16.09085387542, "VEKLURY": 39.63132198673046, "ZYPREXA": 1.5843542372449295, "null": 1.677995565567857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7381.json
index daf2c377ae1..19a6fcf82e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7381.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7381.json
@@ -1 +1 @@
-{"OPTIMARK": 243.49001473448632}
\ No newline at end of file
+{"BUDESONIDE": 86.33677395707004, "FENTANYL": 25.824310309853463, "MIDAZOLAM": 78.82579255601317, "SPINRAZA": 111.4787948553636, "null": 0.6801074759050035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7382.json
index aed694d02af..bcd37a4b969 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7382.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7382.json
@@ -1 +1 @@
-{"ADCIRCA": 42.51443995325182, "AZATHIOPRINE": 11.453699101396577, "CELLCEPT": 4.643109913595381, "CICLOSPORIN": 10.63797234053519, "HUMALOG": 1.1481649012711197, "ICLUSIG": 9.602887915914474, "IMATINIB": 21.877934745389677, "KEYTRUDA": 1.908887703734563, "MYCOPHENOLATE": 11.16677317624642, "OFEV": 8.986190619908276, "OPSUMIT": 25.40315210121928, "OPTIMARK": 9.518087790306872, "PEMETREXED": 22.765918159140377, "REVATIO": 31.68006842856338, "SOLIRIS": 4.50555135793533, "TRACLEER": 38.12374010520422, "XELJANZ": 1.4162782339370732}
\ No newline at end of file
+{"null": 4.466202627667591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7383.json
index 04342d77216..a45b10afa59 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7383.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7383.json
@@ -1 +1 @@
-{"null": 4.492837504195562}
\ No newline at end of file
+{"BUPRENORPHINE": 55.59692578680711, "SUBOXONE": 62.30094742518276, "null": 1.1311436028399546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7384.json
index 958942651d2..51ce01c9af8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7384.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7384.json
@@ -1 +1 @@
-{"null": 1.4952445862083286}
\ No newline at end of file
+{"null": 1.145626223782917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7385.json
index 5784e1849ae..b9bf0fd155a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7385.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7385.json
@@ -1 +1 @@
-{"ADENURIC": 13.97655697077372, "BIKTARVY": 3.682927665137964, "CYMBALTA": 10.161214654811335, "DULOXETINE": 3.9648033262674818, "ENBREL": 1.7957135609454364, "FORSTEO": 1.5287725602711133, "GARDASIL": 3.064880378955511, "NAGLAZYME": 7.538732418272471, "NUTROPIN": 165.5105509865673, "OMNITROPE": 42.924190453972365, "SOMATROPIN": 87.56623486100816, "SPINRAZA": 396.9027946407125, "SUBOXONE": 1.733096383923776, "XELJANZ": 1.4915173730104572, "ZOSTAVAX": 4.410059229193188, "null": 1.6310629253354578}
\ No newline at end of file
+{"COMBIVIR": 41.224156739232924, "null": 4.020015002158473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7386.json
index 466b5485c7a..0e6c0b7bf51 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7386.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7386.json
@@ -1 +1 @@
-{"CHAMPIX": 1.0993505799706795, "CLOPIDOGREL": 1.0222416194887876, "COSENTYX": 5.547707903406603, "ELIQUIS": 2.570183969435943, "EUCREAS": 14.68221026310497, "FENTANYL": 2.553297347308721, "HEXYON": 248.62180176241336, "HUMALOG": 1.4833492888462203, "IBRANCE": 2.134318822522298, "INFANRIX": 19.85438928934217, "MMRVAXPRO": 28.134086092751165, "NUCALA": 5.729787806531688, "OMALIZUMAB": 11.26370358883795, "PEGINTRON": 1.4287912117385912, "PREVENAR": 19.639214333628622, "SHINGRIX": 1.489855972726689, "SUTENT": 1.0060637387735984, "XELJANZ": 1.763862381672022, "XOLAIR": 4.281244513369621}
\ No newline at end of file
+{"SUBOXONE": 33.18238277641164, "null": 1.0977582360729263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7387.json
index 8ad77318221..fe0095ea052 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7387.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7387.json
@@ -1 +1 @@
-{"ABILIFY": 2.157681560492145, "BRIVIACT": 8.222162567088276, "CARBIDOPA": 12.760907059001465, "CHAMPIX": 1.4579157160055385, "CYMBALTA": 1.12297403472002, "FENTANYL": 1.2520670303987784, "GARDASIL": 1.080436195653211, "HEXYON": 68.83905875963742, "INFANRIX": 62.76401516082001, "KEPPRA": 3.908187176926599, "LATUDA": 6.0883371726773685, "LEVETIRACETAM": 1.6220860411223164, "MMRVAXPRO": 61.73822130358348, "NIMENRIX": 2.726265091401973, "PREVENAR": 33.56137946092968, "ROTATEQ": 30.956921983246534, "TAMIFLU": 6.345873868592912, "VIMPAT": 3.666126751812902, "null": 2.3745870566426714}
\ No newline at end of file
+{"COMIRNATY": 0.8625568390999593, "null": 0.392791671330542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7388.json
index 8b098f3ab0f..978a8eaa610 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7388.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7388.json
@@ -1 +1 @@
-{"JARDIANCE": 136.35646859542538}
\ No newline at end of file
+{"null": 0.9004185235913372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7389.json
index 511099a0281..678cfbfacdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7389.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7389.json
@@ -1 +1 @@
-{"null": 2.539441762444792}
\ No newline at end of file
+{"CUBICIN": 237.4138931489093, "null": 0.4175806272323522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/739.json
index 5d6c70b4a75..80525c8fa25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/739.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/739.json
@@ -1 +1 @@
-{"ALISKIREN": 4.502040066685692, "AVANDAMET": 4.80374648200177, "AVANDIA": 6.017028078682692, "BRIDION": 3.552249041341651, "BRILIQUE": 8.102148052044232, "CLOPIDOGREL": 1.174621041278289, "COAPROVEL": 3.5712353484475465, "CORTICOSTEROIDS": 26.20967723560282, "EBIXA": 11.995956631558204, "ENTRESTO": 2.6746104957443557, "EXELON": 14.675575961666516, "EXFORGE": 1.218283590386031, "FENTANYL": 1.7670293358980431, "JANUMET": 1.2287382984647592, "JARDIANCE": 1.2814848408709834, "KALETRA": 2.532749644549217, "KEPPRA": 1.2373242443460148, "LACOSAMIDE": 5.693912997976467, "LEVEMIR": 1.9064953378008744, "MIDAZOLAM": 4.919717117374876, "PLAVIX": 1.1062907754537803, "PROPRANOLOL": 5.165848409677793, "RAPISCAN": 57.79364215928979, "RASILEZ": 3.3427948123194016, "SUFENTANIL": 7.754753396190877, "TASIGNA": 1.4113540824456936, "TICAGRELOR": 5.77635850162484, "TRELEGY": 2.5449357182901884, "TRULICITY": 1.4534477030532194, "VFEND": 1.560483443938881, "VIAGRA": 1.692946947803659, "VIMPAT": 17.732712575178837, "null": 3.1220676030718284}
\ No newline at end of file
+{"ARANESP": 92.88429352086015, "CELLCEPT": 12.303962947268866, "EPOETIN": 675.2947513744114, "MYCOPHENOLATE": 62.32364709530312, "null": 2.019161749522304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7390.json
index f276fd08e08..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7390.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7390.json
@@ -1 +1 @@
-{"NEXAVAR": 49.05166207153078, "SUTENT": 9.50916987747825}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7391.json
index dbbfab98fde..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7391.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7391.json
@@ -1 +1 @@
-{"null": 2.6473914494403386}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7392.json
index bb5bdf448bb..2626bc15737 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7392.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7392.json
@@ -1 +1 @@
-{"null": 1.0924667414613298}
\ No newline at end of file
+{"VOTRIENT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7393.json
index a0454af4327..e075f99b903 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7393.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7393.json
@@ -1 +1 @@
-{"ASPARAGINASE": 136.08489480916026, "JARDIANCE": 35.8951595431591}
\ No newline at end of file
+{"ADCIRCA": 206.16236740389, "null": 0.7506148999354055}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7394.json
index ae051362312..2b3ab135957 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7394.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7394.json
@@ -1 +1 @@
-{"ASPARAGINASE": 22.04026547274284, "null": 1.2551409800392062}
\ No newline at end of file
+{"CLOPIDOGREL": 53.61782622724356, "null": 1.6593644968312498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7395.json
index 4a4e14d2d18..9a9346a215f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7395.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7395.json
@@ -1 +1 @@
-{"TOZINAMERAN": 2.03600058623516, "null": 1.3817916329192992}
\ No newline at end of file
+{"null": 1.514987313588726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7396.json
index cf7289cb7a6..fd0151db097 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7396.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7396.json
@@ -1 +1 @@
-{"JARDIANCE": 7.435794129940771, "PEGASYS": 2.8410989769345627, "null": 1.0912340069555202}
\ No newline at end of file
+{"PEMBROLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7397.json
index cffe763f6be..1c90e5dfc40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7397.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7397.json
@@ -1 +1 @@
-{"null": 1.074688907439278}
\ No newline at end of file
+{"STIVARGA": 24.471039095289207, "null": 0.3597703699908762}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7398.json
index 31b04a5033d..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7398.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7398.json
@@ -1 +1 @@
-{"AIMOVIG": 1.243578461267613, "AVAMYS": 9.67220499431581, "BUDESONIDE": 1.0807535545414868, "CAPECITABINE": 2.6089002840507303, "COSENTYX": 1.225822202011659, "ENTRESTO": 1.4843534626214197, "FASENRA": 2.3333526677452032, "FLUTICASONE": 16.44867392666564, "GARDASIL": 2.0593722454874515, "HUMIRA": 2.5029228499892966, "IBRANCE": 1.1591994012591, "MEPOLIZUMAB": 24.76085452096457, "MMRVAXPRO": 1.5660206557195635, "NIMENRIX": 2.3283171001890066, "NUCALA": 12.068956122152686, "OFEV": 3.507581480832375, "OMALIZUMAB": 9.120068804313505, "OPSUMIT": 5.242990050003099, "PANTOPRAZOLE": 6.329050494785357, "SIMPONI": 2.26122216087789, "TOZINAMERAN": 1.7498989027447107, "TRACLEER": 2.364734917583493, "TWINRIX": 11.77671855157093, "UMECLIDINIUM": 23.92225800505608, "XELJANZ": 2.3212835767437463, "XOLAIR": 4.112645436382335, "ZOSTAVAX": 8.261526700599104}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7399.json
index acf57f15efe..c3885628300 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7399.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7399.json
@@ -1 +1 @@
-{"CICLOSPORIN": 48.97799942767748}
\ No newline at end of file
+{"CICLOSPORIN": 10.627860940821453, "null": 1.2300779125851802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/74.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/74.json
index 9c5a4a8ac34..5439bcf473d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/74.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/74.json
@@ -1 +1 @@
-{"CYMBALTA": 3.24561227465808, "FENTANYL": 6.42308397006293, "LACOSAMIDE": 29.165359052692548, "OLANZAPINE": 80.61733219893797, "PREGABALIN": 18.51097915813447, "null": 1.6879640096425974}
\ No newline at end of file
+{"COMIRNATY": 1.2824518052700138}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/740.json
index fe4eafd79a9..afd48e4b0f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/740.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/740.json
@@ -1 +1 @@
-{"AVANDAMET": 7.415844798664104, "AVANDIA": 6.509628127960115, "BRIDION": 19.166788552108677, "BRILIQUE": 20.437484510128336, "EBIXA": 11.699135892539786, "EFAVIRENZ": 5.483628837286245, "FENTANYL": 4.97308995454824, "HARVONI": 1.893422685806995, "IPILIMUMAB": 1.9893538566395728, "KALETRA": 3.344064698185585, "KEPPRA": 1.1676689944852143, "KEYTRUDA": 2.070409462788072, "LACOSAMIDE": 12.777282161773538, "LAMIVUDINE": 4.485437309553661, "MICARDIS": 3.53843112563667, "OPDIVO": 1.4541606254899682, "PEMBROLIZUMAB": 3.719383453620359, "RAPISCAN": 50.46396821372571, "TELMISARTAN": 5.830511208547697, "TICAGRELOR": 6.731418726769471, "VFEND": 1.6861828414930242, "VIMPAT": 16.681126822021746, "null": 3.4066641739005794}
\ No newline at end of file
+{"ARANESP": 190.25223389960428, "EPOETIN": 349.5703420902292, "NEORECORMON": 816.2697011790758, "PEGASYS": 1.7488480861322795, "null": 2.470657122681232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7400.json
index 690523d3230..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7400.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7400.json
@@ -1 +1 @@
-{"null": 3.666842685011703}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7401.json
index b21614f6622..fa1e4723eb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7401.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7401.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 15.710317257862553, "BUPRENORPHINE": 5.307505567934524, "ENBREL": 3.467001797816167, "IRESSA": 13.181554866463816, "ZOSTAVAX": 14.317317930714903}
\ No newline at end of file
+{"OPSUMIT": 75.40330453227536, "TRACLEER": 47.81268563204908, "null": 1.1804774994225942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7402.json
index bedfc601aa9..7a24dd582c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7402.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7402.json
@@ -1 +1 @@
-{"COSENTYX": 21.611715625301198, "ELIQUIS": 2.9486444982725044, "ZOSTAVAX": 60.672912563595176}
\ No newline at end of file
+{"BUPIVACAINE": 290.561436128705, "FENTANYL": 28.24660178219941, "null": 1.350102583130608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7403.json
index 1672a57f809..ba95213aeee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7403.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7403.json
@@ -1 +1 @@
-{"ADCETRIS": 35.24043607138998, "AFINITOR": 8.531782974896268, "ASPARAGINASE": 11.1642737739218, "AZACITIDINE": 5.261337700330448, "BEVACIZUMAB": 2.515316780227105, "BLINATUMOMAB": 16.436010274694794, "BORTEZOMIB": 6.2689706562796434, "BOSULIF": 28.95057316394313, "BRAFTOVI": 29.646028287291344, "BUSULFAN": 5.633053036629699, "CAELYX": 3.849320436811404, "CAPECITABINE": 2.5380330630428176, "CARMUSTINE": 38.05057265653156, "CHLORMETHINE": 223.8543905293455, "CYTARABINE": 11.658445398650723, "DEXAMETHASONE": 2.058259686700416, "DOCETAXEL": 7.366515751135224, "DOXORUBICIN": 25.89722789329935, "FASLODEX": 3.717046183262071, "FULVESTRANT": 2.633145386339633, "GLIVEC": 22.180719621427308, "IBRANCE": 30.318219119167768, "IMATINIB": 30.34395867149284, "INLYTA": 21.67308190083684, "JAKAVI": 75.7229662116623, "KISQALI": 4.840285452898643, "KYMRIAH": 20.21401009052694, "MEKINIST": 13.001679803304334, "METHOTREXATE": 2.266190270595195, "NILOTINIB": 36.12489304745866, "NOT": 3.2761814822481186, "PACLITAXEL": 6.264088195099037, "RITUXIMAB": 7.716291209636893, "RUXOLITINIB": 125.6648281816963, "SUTENT": 18.21572432809746, "TASIGNA": 36.74854294651669, "THIOTEPA": 28.662096829500527, "VOTRIENT": 4.516309952548652, "XALKORI": 10.644337466105158}
\ No newline at end of file
+{"ARAVA": 2.9917569665789454, "HUMIRA": 19.10244329199644, "SIMPONI": 12.883539110799138, "null": 0.7683205756822835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7404.json
index 6169ebdd5c1..daf7975d7ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7404.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7404.json
@@ -1 +1 @@
-{"BUDESONIDE": 2.69330128717895, "CANAKINUMAB": 471.6832882559841, "HYDROCORTISONE": 13.431084300848052, "IPILIMUMAB": 57.4108844572086, "KEYTRUDA": 34.77683289321213, "OPDIVO": 214.4315939123931, "PEMBROLIZUMAB": 18.566455566098043, "RITONAVIR": 391.7042329091548}
\ No newline at end of file
+{"null": 1.6210800635805371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7405.json
index 9c9ae314fe6..d1d723871a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7405.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7405.json
@@ -1 +1 @@
-{"NEXAVAR": 12.399022293355722, "STIVARGA": 25.820594936627167}
\ No newline at end of file
+{"AVONEX": 565.2076161646444, "FORSTEO": 27.189727481559476, "null": 0.6535070563689462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7406.json
index 3aadfcba763..6ed6d3e8c0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7406.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7406.json
@@ -1 +1 @@
-{"null": 1.9010072410948389}
\ No newline at end of file
+{"OPSUMIT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7407.json
index eff08f9ff5b..d32597a59f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7407.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7407.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 45.783319740548585, "null": 1.9276101420341336}
\ No newline at end of file
+{"PANTOPRAZOLE": 512.5728492782512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7408.json
index 2d7d2883da3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7408.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7408.json
@@ -1 +1 @@
-{"ASPARAGINASE": 776.0485639878335, "CICLOSPORIN": 14.867153340335117, "CYTARABINE": 29.495923097894487, "DOXORUBICIN": 28.64619921081292}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7409.json
index 79cba3488bc..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7409.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7409.json
@@ -1 +1 @@
-{"AUBAGIO": 89.49016462666093, "BETAFERON": 75.64917814063908, "FAMPYRA": 421.7103540247612, "KESIMPTA": 100.80460411597666, "PLEGRIDY": 63.022141084009775}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/741.json
index 0bb9d9b8c38..b0c7925e37f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/741.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/741.json
@@ -1 +1 @@
-{"APIXABAN": 2.7007338246227097, "AVANDIA": 4.489160933955906, "DENOSUMAB": 44.58159574087806, "ENTRESTO": 3.1617787388566314, "IRBESARTAN": 7.00850753482841, "IRON": 25.392009194216357, "JANUMET": 1.940454738676591, "JANUVIA": 2.5940617338730334, "JARDIANCE": 1.47367121759475, "KALETRA": 3.889540288050576, "KEPPRA": 1.777067538917349, "LACOSAMIDE": 10.593833958024645, "LEVETIRACETAM": 2.115235232549741, "LYRICA": 1.7607619566322303, "OLANZAPINE": 2.317278643333808, "SPIRONOLACTONE": 35.292927625036306, "VIMPAT": 9.6620518278023, "ZYPREXA": 1.5980848446627307, "null": 3.3095953342670037}
\ No newline at end of file
+{"PEGASYS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7410.json
index 7403f27bb68..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7410.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7410.json
@@ -1 +1 @@
-{"COVID19": 1.0345366172734167, "ROTATEQ": 137.78317015243871, "ZOSTAVAX": 80.56599852933752, "null": 1.0585770410114614}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7411.json
index bc4b6e978f7..f16ee10de1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7411.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7411.json
@@ -1 +1 @@
-{"AVAMYS": 63.076199352665874, "BENLYSTA": 3.135167868643157, "BENRALIZUMAB": 13.667022681993576, "BUDESONIDE": 2.8572194683161114, "CHOLESTAGEL": 128.6519703463677, "COSENTYX": 3.0352745286884857, "ESBRIET": 2.4721614474067963, "FASENRA": 8.840548957168602, "FLUTICASONE": 12.738943698799538, "INCRUSE": 5.714809058740615, "JARDIANCE": 1.1721663819742827, "KAFTRIO": 6.9055992630144605, "MEPOLIZUMAB": 6.842564032850573, "NAGLAZYME": 15.197310440512474, "NUCALA": 11.021208206452304, "OMALIZUMAB": 8.034700169657185, "OPSUMIT": 2.1248395664729496, "RELVAR": 14.602789823252406, "REMICADE": 6.240882597623904, "SPINRAZA": 6.885173133584046, "SUTENT": 1.148600751745695, "SYNAGIS": 4.205386222193698, "TRELEGY": 11.239389947321664, "XELJANZ": 2.0137728171923617, "XOLAIR": 4.859287380261092, "null": 1.022986521018105}
\ No newline at end of file
+{"FAMPRIDINE": 4436.643070289055}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7412.json
index dcf4453f418..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7412.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7412.json
@@ -1 +1 @@
-{"ABILIFY": 25.499697330069573, "AIMOVIG": 3.2701500683888534, "AMBROXOL": 133.3674006465891, "AMLODIPINE": 111.98748844841803, "ANAGRELIDE": 29.8445940125878, "ARIPIPRAZOLE": 15.833328665914992, "ASENAPINE": 18.927634474977687, "BOTULINUM": 78.85142360540652, "BRINTELLIX": 2.79464008523786, "BRIVIACT": 6.363103093538912, "BUPIVACAINE": 4.90970225699097, "BUPRENORPHINE": 5.074305626637121, "CAFFEINE": 80.51341514140996, "CANNABIDIOL": 9.526209467297024, "CARIPRAZINE": 28.993508603164717, "CIRCADIN": 5.800682164551576, "CYMBALTA": 1.5636199522736431, "DULOXETINE": 4.798771613489257, "EPIDYOLEX": 45.62015425726177, "ESOMEPRAZOLE": 4.098304803508921, "FENTANYL": 6.116253588701886, "FYCOMPA": 2.2902415693451306, "INVEGA": 9.30208094922216, "KEPPRA": 2.1900639436658604, "LACOSAMIDE": 5.622788111011199, "LATUDA": 3.95296038508841, "LEVETIRACETAM": 6.220428126001628, "LEVOFLOXACIN": 39.63139972347844, "LOXAPINE": 14.53558252909778, "LURASIDONE": 18.28555559926985, "LYRICA": 3.2081484307212422, "MIDAZOLAM": 7.712113909653155, "NALOXONE": 20.535025536120216, "OLANZAPINE": 15.90604910459032, "OXYBUTYNIN": 4.30290665048088, "PREGABALIN": 5.442925781659223, "PROPRANOLOL": 2.463916527713876, "RISPERIDONE": 16.58734862341142, "SPIRONOLACTONE": 2.2512968587409645, "SUBOXONE": 1.076254774910367, "SUFENTANIL": 4.0074381768675975, "SYCREST": 38.9396529498552, "VALDOXAN": 9.698695654328173, "VIMPAT": 2.979379989058401, "XYREM": 4.006303483220632, "ZYPADHERA": 106.64327216150753, "ZYPREXA": 7.796374294609893, "null": 1.6233992012615557}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7413.json
index 6f4f43d3f19..d4da1412cc3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7413.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7413.json
@@ -1 +1 @@
-{"ABILIFY": 1.484796021178864, "AGOMELATINE": 50.73090015381563, "AMBROXOL": 426.37345282822974, "AMLODIPINE": 362.1595705485053, "ARIPIPRAZOLE": 29.505922060677715, "BUPIVACAINE": 7.032081718116269, "CAFFEINE": 259.20720900875415, "FENTANYL": 5.152587982187614, "INVEGA": 41.62991226636201, "LATUDA": 3.336596807987536, "LEVETIRACETAM": 2.1573489769450336, "LEVOFLOXACIN": 147.98221380379042, "MIDAZOLAM": 31.106211474758755, "OLANZAPINE": 12.236265745247112, "PREGABALIN": 4.508408088396333, "RISPERIDONE": 11.540622230250191, "SUFENTANIL": 10.832595028660094, "SYCREST": 44.55508030635309, "ZONISAMIDE": 31.296084691284683, "ZYPADHERA": 16.4995846831076, "ZYPREXA": 4.940327508195969, "null": 1.4018562731826114}
\ No newline at end of file
+{"CYMBALTA": 18.671848464295277, "FAMPRIDINE": 2704.271097350109, "PANTOPRAZOLE": 120.36997512141625, "null": 0.5036571925135453}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7414.json
index ffa0a18a386..917c7eb008d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7414.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7414.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2397179902275988}
\ No newline at end of file
+{"KEPPRA": 56.35878721917613, "PANTOPRAZOLE": 147.12300079486812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7415.json
index 655696bd4e9..a55c3d01b62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7415.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7415.json
@@ -1 +1 @@
-{"ABILIFY": 1.2265786830932714, "ALL": 1.7836299710942385, "ALOXI": 1.6744077059869549, "ASPARAGINASE": 2.039071835867569, "AUBAGIO": 1.0827534112078223, "AVONEX": 1.7610913539273656, "AXURA": 2.5009817973841013, "BEDAQUILINE": 1.2891229612763715, "BENZODIAZEPINE": 1.6772337869100145, "BENZODIAZEPINES": 1.716457914909938, "BEXSERO": 3.867691781636057, "BRAFTOVI": 1.0145458068559343, "BRINTELLIX": 1.1632050332136217, "BRIVARACETAM": 16.780753532714236, "BRIVIACT": 17.048341765179778, "BUCCOLAM": 8.831169785531339, "CANNABIDIOL": 6.881879532932979, "CAPRELSA": 1.1633663499445115, "CHAMPIX": 1.1078558541915993, "CICLOSPORIN": 1.222533814356767, "CIDOFOVIR": 1.1141498066086135, "CINRYZE": 1.0059445568199714, "CYMBALTA": 2.253498713015853, "DELAMANID": 2.3762823622854707, "DIACOMIT": 7.189511946676789, "EBIXA": 5.259403588381565, "EMEND": 1.8230796366347424, "ENZALUTAMIDE": 1.2495832304866794, "EPIDYOLEX": 13.843303593399268, "ERLEADA": 1.5129243607801004, "ERTAPENEM": 2.9078166495155826, "ESLICARBAZEPINE": 16.27583576751202, "EXELON": 1.270488070486239, "FAMPRIDINE": 2.232063742664674, "FAMPYRA": 2.5709142900923694, "FENTANYL": 1.140301023685974, "FINTEPLA": 20.686666023072323, "FIRDAPSE": 1.3613406685345908, "FORTOVASE": 2.604130789549862, "FYCOMPA": 9.315850743240084, "GARDASIL": 4.150246637273334, "GILENYA": 1.0880107692725147, "GLIBENCLAMIDE": 1.1089481463711888, "GLUCAGON": 3.52075660027208, "HEXYON": 1.7308443798166937, "HUMAN": 1.0684923949896528, "INFANRIX": 4.902542556980155, "INOVELON": 10.8738292992694, "INTRONA": 1.1045009020418834, "INTUNIV": 6.859615562313105, "INVANZ": 7.380376883964889, "ISOPHANE": 1.7588080579230134, "KEPPRA": 17.915888977898966, "KUVAN": 4.2155182319025855, "LACOSAMIDE": 19.554717323718425, "LATUDA": 2.0623166900481475, "LEVETIRACETAM": 14.79287427356818, "LEVOFLOXACIN": 1.2217621531390304, "LOXAPINE": 2.501151490031622, "LYRICA": 1.3270717253720388, "MEMANTINE": 3.826773694336912, "MENVEO": 1.6631526919187007, "MEXILETINE": 2.761654251671553, "MIDAZOLAM": 2.646600842335089, "MIMPARA": 1.9820280652208535, "MIRCERA": 1.2692792371072903, "MMRVAXPRO": 1.3491746687617203, "NAGLAZYME": 2.4327101910483493, "NIMENRIX": 1.9640656968381551, "NUTROPIN": 2.878030355072476, "OLANZAPINE": 1.1783084096292216, "OMNITROPE": 1.580355576751511, "ONCASPAR": 1.261506936147099, "OPIOIDS": 1.4630743062659768, "OSELTAMIVIR": 1.0047984610918617, "PEGINTRON": 1.2365622528711189, "PERAMPANEL": 5.877154859472207, "PREGABALIN": 1.0242617994458147, "PREVENAR": 3.892739271317128, "PROQUAD": 2.855645143826055, "REBIF": 2.644151316550925, "RISPERIDONE": 1.207475569862395, "ROTARIX": 4.156488645428448, "ROTATEQ": 1.590965930841439, "RUFINAMIDE": 15.031197376624112, "SILGARD": 1.9629371945813068, "SIMEPREVIR": 1.1012333843361464, "SOFOSBUVIR": 1.2035799711245847, "SOLIRIS": 1.109443215705458, "SPINRAZA": 1.0023017529340466, "SUBOXONE": 2.557549528832165, "SYCREST": 1.4766919772181684, "SYNAGIS": 2.0681348325305278, "SYNFLORIX": 2.5738113434731185, "TAMIFLU": 4.228545496225292, "TECFIDERA": 1.0459757136291907, "TEMODAL": 2.1061033414766097, "TEMOZOLOMIDE": 2.1612008364529225, "UNKNOWN": 1.7839409695874633, "VALDOXAN": 1.8895010370335104, "VARICELLA": 7.04383688745487, "VIGABATRIN": 14.97290237231165, "VIMPAT": 16.704293888080826, "XTANDI": 2.361213584828544, "XYREM": 1.6389667785965465, "ZAVESCA": 3.436968238746199, "ZINBRYTA": 1.1236683687810602, "ZONEGRAN": 8.948579498804962, "ZONISAMIDE": 6.66705369873924, "ZYPREXA": 2.3219443366647696, "null": 2.489717367346657}
\ No newline at end of file
+{"KEPPRA": 140.08639902696837}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7416.json
index b0109e23c0c..cf99ee3ac8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7416.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7416.json
@@ -1 +1 @@
-{"null": 2.0600612252546204}
\ No newline at end of file
+{"PANTOPRAZOLE": 157.6368027625852, "null": 0.3612318111490105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7417.json
index 2d06f0629b4..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7417.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7417.json
@@ -1 +1 @@
-{"BRIVIACT": 91.35430651773312, "KEPPRA": 29.673419533482484, "LACOSAMIDE": 71.11065700603598, "LEVETIRACETAM": 73.28533167714178, "VIMPAT": 40.73193805559014, "null": 1.2010296455703555}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7418.json
index 0ccbb63b1a2..1204933093c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7418.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7418.json
@@ -1 +1 @@
-{"CYMBALTA": 1.429676477539695, "FENTANYL": 4.792844770596524, "GARDASIL": 13.101988054353564, "MENVEO": 37.59575455994912, "MIDAZOLAM": 24.69596755079265, "PEGASYS": 1.259387653244573, "SPIKEVAX": 1.0050722057006591, "null": 1.4724530868740822}
\ No newline at end of file
+{"AVONEX": 1024.30826293848, "FAMPRIDINE": 944.4046531340248, "null": 0.8027168745304344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7419.json
index 4347b2df366..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7419.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7419.json
@@ -1 +1 @@
-{"null": 1.1422246581022015}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/742.json
index c701d857a33..b96c83840b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/742.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/742.json
@@ -1 +1 @@
-{"AVANDIA": 5.728504500486245, "BRIDION": 16.316887435279643, "BRILIQUE": 12.92739528985086, "EBIXA": 27.534798862086973, "FENTANYL": 6.251679778542808, "HARVONI": 4.984759500746836, "LACOSAMIDE": 16.249035453385087, "LEVETIRACETAM": 2.207083209496211, "PEGINTRON": 1.3539639283744935, "VIMPAT": 23.20596074028522, "ZYPREXA": 2.965062409514157, "null": 2.451064112069192}
\ No newline at end of file
+{"HUMALOG": 43.083850655068176, "INSULIN": 104.9682555627916, "LEVEMIR": 60.50790089146852, "NOVORAPID": 286.4124909198226, "null": 0.1468722345127586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7420.json
index 33c14b3f1ad..15b19fccee4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7420.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7420.json
@@ -1 +1 @@
-{"SUBOXONE": 65.30446761546476, "null": 1.4064643214038297}
\ No newline at end of file
+{"null": 0.4463192061723124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7421.json
index a28b2e2012c..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7421.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7421.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 5.307505567934524, "LEVETIRACETAM": 4.855196571912353, "OLANZAPINE": 7.248597172564195, "ROTATEQ": 16.760705427012635, "SUBOXONE": 40.35833863116071, "SYNAGIS": 41.05370331781002, "ZYPREXA": 3.9440043436217342, "null": 2.62321703963181}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7422.json
index f1353948fef..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7422.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7422.json
@@ -1 +1 @@
-{"CHAMPIX": 7.014420232136416, "GARDASIL": 3.197060104500168, "ZYPREXA": 7.115552077342087, "null": 3.711796527900934}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7423.json
index d21d25573f9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7423.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7423.json
@@ -1 +1 @@
-{"null": 3.018048574023795}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7424.json
index 985399de7a6..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7424.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7424.json
@@ -1 +1 @@
-{"COSENTYX": 65.1095301150832}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7425.json
index e747b9f18be..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7425.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7425.json
@@ -1 +1 @@
-{"ABILIFY": 6.792979480540944, "ARIPIPRAZOLE": 4.178092668908295, "BRINTELLIX": 7.692208537290067, "BRIVIACT": 18.1784230792798, "BUPRENORPHINE": 5.285419918779858, "CHAMPIX": 4.324109170815182, "CYMBALTA": 4.050658288133336, "FYCOMPA": 9.94347716623241, "IBUPROFEN": 1.7415649546051115, "INVEGA": 122.61966924730778, "KAFTRIO": 6.291342630540044, "KEPPRA": 8.273992609612744, "LATUDA": 15.265871679827743, "LEVETIRACETAM": 4.109508004727169, "OLANZAPINE": 7.412572695582197, "PEGASYS": 1.2968410585849846, "PEGINTRON": 1.22228486044306, "RISPERIDONE": 19.716546210210144, "SUBOXONE": 1.297937665357326, "SYMTUZA": 50.20958343048842, "TAMIFLU": 4.547461525569352, "ZYPREXA": 4.659190558155582, "null": 3.301920383756484}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7426.json
index ad9d9f9c05d..83c49d61f11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7426.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7426.json
@@ -1 +1 @@
-{"null": 3.711071323108152}
\ No newline at end of file
+{"NEULASTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7427.json
index aee623dd577..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7427.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7427.json
@@ -1 +1 @@
-{"ABILIFY": 2.710593751162179, "ALLI": 198.9899244718566, "ARIPIPRAZOLE": 2.8863381867070266, "BRINTELLIX": 18.78436985313768, "CHAMPIX": 34.66549004350117, "CYMBALTA": 4.199279031616839, "DULOXETINE": 10.122079284943467, "KEPPRA": 3.391359263937669, "LATUDA": 25.60733161160183, "OLANZAPINE": 8.087415747447604, "PEGASYS": 5.67433429611298, "SAXENDA": 5.762730828408215, "ZYPREXA": 4.0223846981473885, "null": 1.9732735478255472}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7428.json
index 0d7574ccccb..59de4873846 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7428.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7428.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 8.77257362637516, "CYMBALTA": 1.5196254220573453, "IBUPROFEN": 9.622286655536966, "OLANZAPINE": 3.2192548459282504, "SILDENAFIL": 20.359204309053364, "TESTOSTERONE": 59.12310105212452, "TREMFYA": 14.05492615559688, "null": 4.047073104098589}
\ No newline at end of file
+{"null": 0.7688781030861545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7429.json
index f40f451c956..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7429.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7429.json
@@ -1 +1 @@
-{"null": 5.518972311993257}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/743.json
index 76f090b13e6..77b760a3775 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/743.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/743.json
@@ -1 +1 @@
-{"null": 4.321368662114901}
\ No newline at end of file
+{"APIDRA": 59.32902051324072, "HUMALOG": 45.96671666857312, "INSULIN": 102.06150794099568, "LANTUS": 11.482415684585735, "LEVEMIR": 42.23677836538053, "NOVORAPID": 110.02584984028977, "null": 0.1692505672222768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7430.json
index 25825f6c3d4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7430.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7430.json
@@ -1 +1 @@
-{"RINVOQ": 289.0849879776245}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7431.json
index 1c472909aaf..0a8d8210dac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7431.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7431.json
@@ -1 +1 @@
-{"null": 4.087854129026545}
\ No newline at end of file
+{"RENVELA": 51920.25683250734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7432.json
index 84482becd6e..1e02e623a53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7432.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7432.json
@@ -1 +1 @@
-{"null": 9.169036285391323}
\ No newline at end of file
+{"null": 0.6378939197264512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7433.json
index 6dd64630fd6..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7433.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7433.json
@@ -1 +1 @@
-{"null": 16.462340495407062}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7434.json
index 7248288c5fd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7434.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7434.json
@@ -1 +1 @@
-{"VIAGRA": 828.1244651341824}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7435.json
index 21fdff25b25..77955b3c42d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7435.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7435.json
@@ -1 +1 @@
-{"OLANZAPINE": 58.66441877481463}
\ No newline at end of file
+{"ATRIPLA": 14.768980779681495, "null": 0.4268472894223336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7436.json
index 7c2d2c72ad5..3bb09c6f397 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7436.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7436.json
@@ -1 +1 @@
-{"ELIQUIS": 5.744455454513274, "null": 1.4916874260901711}
\ No newline at end of file
+{"COMIRNATY": 1.0603781921777309, "null": 0.7249090823245044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7437.json
index 978e3111a94..41b1ef3e888 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7437.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7437.json
@@ -1 +1 @@
-{"COVID19": 1.5626519803506609, "SPIKEVAX": 1.3740775732918753, "TOZINAMERAN": 2.2680398052527977, "VAXZEVRIA": 1.3348423407280208}
\ No newline at end of file
+{"BUPIVACAINE": 292.7202357853307, "SUBOXONE": 60.93380293075059, "null": 0.6552834570939439}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7438.json
index 46dc46c7767..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7438.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7438.json
@@ -1 +1 @@
-{"CHOLESTAGEL": 100.13469470087064, "COMIRNATY": 1.983885153454056, "COSENTYX": 1.4561825306833631, "GARDASIL": 1.170241482109222, "HUMIRA": 1.0405033127540957, "TOZINAMERAN": 1.8207144810692293, "TRELEGY": 1.2847069222462428, "XOLAIR": 3.1418626587713843, "null": 1.7490198748117958}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7439.json
index 067a5291326..314e55022cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7439.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7439.json
@@ -1 +1 @@
-{"BENRALIZUMAB": 35.4865654618466, "BRILIQUE": 4.6401751650130505, "CAELYX": 11.278713760496354, "CHAMPIX": 1.1455992437865046, "COMIRNATY": 1.8948076534798088, "DEXAMETHASONE": 2.1616747697305048, "MEPOLIZUMAB": 3.977383201998281, "NUCALA": 5.056920313384757, "SPIKEVAX": 1.52043126752263, "VAXZEVRIA": 1.4279207135810443, "null": 1.2551880377448643}
\ No newline at end of file
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/744.json
index 4fb530bad8a..9e1809058ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/744.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/744.json
@@ -1 +1 @@
-{"BOTULINUM": 165.76930180517869, "NORVIR": 156.6128739519058, "OLANZAPINE": 13.633059911382356, "null": 1.5673727399239168}
\ No newline at end of file
+{"APIDRA": 85.91391116760417, "HUMALOG": 44.50685455279834, "INSULIN": 86.2550002319259, "LANTUS": 35.353705355060434, "LEVEMIR": 65.535456129277, "NOVORAPID": 125.73687280565656, "null": 0.1422369534974197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7440.json
index bd57d6a9725..4d677817413 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7440.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7440.json
@@ -1 +1 @@
-{"APIXABAN": 820.9594728517388, "ELIQUIS": 9.416322588777582, "ESOMEPRAZOLE": 16.793746205359273}
\ No newline at end of file
+{"null": 0.9766116568776682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7441.json
index c3eee12784b..9ed96e3a06b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7441.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7441.json
@@ -1 +1 @@
-{"COVID19": 3.955656354555195, "HYDROCORTISONE": 4.745629469118601, "OPTIMARK": 1.6687339907962622, "SHINGRIX": 2.130809912542475, "SPIKEVAX": 1.6625323431921029, "SUTENT": 1.504645090998562, "TOZINAMERAN": 18.084999044892168, "VAXZEVRIA": 1.2809581065057538, "ZOSTAVAX": 1.090015484922965}
\ No newline at end of file
+{"SUBOXONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7442.json
index 4f7eb82084a..a69846ea5de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7442.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7442.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.0342483361797563, "ARAVA": 2.342490154516256, "ENBREL": 5.347718137703639, "HUMIRA": 3.897885747503868, "IBRANCE": 2.2702795348853173, "NUCALA": 4.195474716363843, "OMALIZUMAB": 69.57827674274456, "XELJANZ": 74.79239676759381, "XOLAIR": 6.485839434529864, "null": 1.1831267377896224}
\ No newline at end of file
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7443.json
index 3a0c3dd44d1..d4892bcaadb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7443.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7443.json
@@ -1 +1 @@
-{"COMIRNATY": 1.106788944235319, "null": 1.3558170778616707}
\ No newline at end of file
+{"ABATACEPT": 2.5690288933952465, "ABILIFY": 1.143526408396004, "ACTOS": 4.339307089340261, "ACTRAPID": 4.693144017178753, "ADALIMUMAB": 2.1332638559199517, "AERIUS": 1.8658767691554348, "ALIMTA": 0.3488164189870421, "ALISKIREN": 6.188929594928199, "AMINOSALICYLIC": 0.4545772317183454, "ANAKINRA": 1.388331247379529, "APIDRA": 7.344471611848577, "APIXABAN": 0.8560463327164398, "APREPITANT": 1.64070906016123, "APROVEL": 3.610546537199228, "ARANESP": 0.2374691485864933, "ARIPIPRAZOLE": 0.714398084489623, "AVASTIN": 0.3169294615747647, "BONVIVA": 1.4831084642710624, "BORTEZOMIB": 1.1117957446525744, "BRILIQUE": 0.5732132577508503, "BRINTELLIX": 0.2518450284721422, "BUDESONIDE": 0.143380900212179, "BUPIVACAINE": 1.761867027812484, "BUPRENORPHINE": 0.7229894985409999, "BYDUREON": 0.3608887553501228, "BYETTA": 0.7664995005297036, "CELLCEPT": 0.5847697129975071, "CHAMPIX": 0.3939037640765651, "CHLORHEXIDINE": 3.642396554234201, "CICLOSPORIN": 0.1137928489759824, "CIMZIA": 1.877963304221208, "CLOPIDOGREL": 2.0504130411242265, "COAPROVEL": 4.134547413580035, "COMBIVIR": 0.9437730468178192, "COMIRNATY": 0.1037127863579358, "COSENTYX": 0.2212736320459528, "CYMBALTA": 0.7585684628799565, "DEXAMETHASONE": 0.5852560696291561, "DULOXETINE": 2.1400152344802525, "EBIXA": 2.436161884917355, "ELIQUIS": 0.7542084663348416, "EMPAGLIFLOZIN": 3.256373327754482, "ENOXAPARIN": 0.9777931390568222, "ENTRESTO": 0.2681875780101722, "ERELZI": 4.270305774016305, "ESBRIET": 0.923716618806254, "ESOMEPRAZOLE": 0.8414479269450624, "EVISTA": 0.6881578490676897, "EVRA": 5.026757359173626, "EXFORGE": 1.0916863834132555, "FASLODEX": 0.2649852360045525, "FENTANYL": 2.240946725219929, "FORSTEO": 0.2872957498684551, "FORXIGA": 0.4062397713447555, "GARDASIL": 1.4612403711310582, "GLIBENCLAMIDE": 5.298751643183773, "HUMALOG": 3.285466832173141, "HYDROCORTISONE": 3.863950162006588, "IBUPROFEN": 4.122416061940643, "INCIVO": 0.8007869495912101, "INSULIN": 2.3442896045608816, "IRBESARTAN": 1.2323821986888506, "JANUMET": 0.3500947857727864, "JANUVIA": 1.0190976808470056, "JARDIANCE": 0.7816152585795987, "KALETRA": 0.4649952241362172, "KEPPRA": 1.7196793635300731, "LACOSAMIDE": 4.813207119092383, "LANTUS": 4.56319589377605, "LEVEMIR": 1.214101414543005, "LEVETIRACETAM": 0.6289675198741309, "LEVOFLOXACIN": 0.7927153743080378, "LIXIANA": 0.7055617681999937, "LURASIDONE": 14.31284217940392, "LYRICA": 0.6289608889742141, "METHOTREXATE": 0.6126448829112373, "MICARDIS": 1.5232290579904733, "MIDAZOLAM": 2.269003938205021, "MMRVAXPRO": 0.5796396511951775, "MULTAQ": 0.7097672264507782, "NEULASTA": 0.7217090665989961, "NEVANAC": 18.065808916808177, "NOVONORM": 3.409476430489664, "NOVORAPID": 3.0546814197193, "NPLATE": 0.6650073217180762, "OLANZAPINE": 1.493774331335095, "OXYBUTYNIN": 2.1134511171033488, "PANTOPRAZOLE": 0.4754103468118829, "PEGASYS": 0.8106861340954215, "PEGINTRON": 0.5791568706363075, "PLAVIX": 0.5579655547564445, "PREGABALIN": 0.6915637868248711, "RANOLAZINE": 2.5666946456225723, "REPAGLINIDE": 17.68794989665085, "ROACTEMRA": 0.8796623161048899, "ROTATEQ": 0.7597627981425072, "SAXENDA": 0.3758446990234306, "SIFROL": 2.6370461751022813, "SIMPONI": 0.7862747472005931, "SPIKEVAX": 0.0907654053847815, "SPIRONOLACTONE": 3.733613773771204, "STALEVO": 1.825319677667234, "STELARA": 0.1973176701282307, "STRIBILD": 0.2242317531443771, "SUTENT": 0.0491600570425147, "TAMIFLU": 1.7111134402767867, "TOZINAMERAN": 0.1310761147750824, "UNSPECIFIED": 4.27734081669384, "VAXZEVRIA": 0.3000213698133884, "VFEND": 0.3654213501488563, "VIAGRA": 0.3713042314858886, "VIMPAT": 0.794685702570827, "VOTRIENT": 0.2119938944641974, "XARELTO": 1.3500360632767474, "XOLAIR": 0.1390108141426045, "ZOSTAVAX": 1.4017609005811866, "ZYPREXA": 0.9129822176304272, "null": 3.133852788242201}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7444.json
index b7a918c9bfd..abb028cb5ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7444.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7444.json
@@ -1 +1 @@
-{"ADENURIC": 2.8412808358131, "APIDRA": 1.1080963548283516, "AUBAGIO": 4.235154490814195, "BETAFERON": 2.8814928679209904, "BUPIVACAINE": 2.0445972817076647, "COMBIVIR": 1.2414436341198405, "COMIRNATY": 2.0476264854854485, "CYMBALTA": 23.245802368493333, "FAMPYRA": 3.2550162012007764, "FENTANYL": 1.1854531062679976, "GARDASIL": 5.816793233418414, "KESIMPTA": 3.839782968214692, "LEMTRADA": 1.976873055239337, "MAVENCLAD": 2.6691916818738584, "PLEGRIDY": 1.7024178721551415, "RASILEZ": 1.678252585974623, "SHINGRIX": 1.241802603010055, "SPINRAZA": 1.1425940785234052, "TWINRIX": 6.242004318535405, "VAXZEVRIA": 2.476252389051451, "XELODA": 2.5989980533656034}
\ No newline at end of file
+{"AIMOVIG": 57.02602965449493, "IBUPROFEN": 38.600606785520434, "VAXZEVRIA": 0.4932495490574075, "null": 2.141432534732575}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7445.json
index 6ddd67c5ff4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7445.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7445.json
@@ -1 +1 @@
-{"null": 3.9844657603791687}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7446.json
index a9f7e6be439..007a134b887 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7446.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7446.json
@@ -1 +1 @@
-{"COMIRNATY": 5.669066257379607, "GARDASIL": 2.025440118718391, "SPIKEVAX": 1.7037476202538506, "VAXZEVRIA": 2.902059267636366}
\ No newline at end of file
+{"BYETTA": 55.72367560562081, "TRULICITY": 50.0158035998072, "VICTOZA": 180.5328882566851, "null": 0.0979121076335924}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7447.json
index f829c3af72d..f2a0a12a408 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7447.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7447.json
@@ -1 +1 @@
-{"ALISKIREN": 41.67292585129446, "APIDRA": 1.3394041427585082, "AUBAGIO": 3.4799697851754465, "BOSULIF": 3.422057776888627, "BUPIVACAINE": 7.999115264772319, "BUSULFAN": 1.3094897433986843, "CHAMPIX": 1.4068854403193565, "CLOPIDOGREL": 1.142320264523998, "COAPROVEL": 3.473306909192497, "COMIRNATY": 1.0270747887161356, "COSENTYX": 1.686447247026457, "COVID19": 1.2934080919054518, "ENOXAPARIN": 2.4512796741872647, "EXFORGE": 1.1848904221298084, "FENTANYL": 2.9404683693109024, "GARDASIL": 3.359104150906897, "KEPPRA": 1.1013215210906542, "LANTUS": 1.4180617927063737, "LYRICA": 2.7508140847018545, "MICARDIS": 1.5082271248669146, "MIDAZOLAM": 1.772412702825633, "ROACTEMRA": 1.0028773802008533, "SHINGRIX": 1.5056674170729942, "TASIGNA": 2.206685171643554, "TOZINAMERAN": 2.1462962080410457, "TWINRIX": 2.6068147951063496, "VAXZEVRIA": 1.115585656586851, "VIAGRA": 1.022149459979716, "ZOSTAVAX": 1.3731006633906706}
\ No newline at end of file
+{"null": 2.15041656941583}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7448.json
index cd017ebccb1..0241d1212ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7448.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7448.json
@@ -1 +1 @@
-{"COMIRNATY": 2.5271921094498424, "COVID19": 1.76567990485935, "SPIKEVAX": 1.4909282837379194}
\ No newline at end of file
+{"THIOTEPA": 2815.918222338205, "null": 1.0424996685900758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7449.json
index ab6b54e37ff..9e9b734524c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7449.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7449.json
@@ -1 +1 @@
-{"AVAMYS": 57.05568389839017, "null": 1.242880835418436}
\ No newline at end of file
+{"LEVOFLOXACIN": 7.53464805309072, "OLANZAPINE": 9.862532789941936, "OXYBUTYNIN": 46.68457477866456, "null": 2.323868294713656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/745.json
index 59db88e4b0b..558aed6150f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/745.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/745.json
@@ -1 +1 @@
-{"null": 1.35440634945964}
\ No newline at end of file
+{"BETAFERON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7450.json
index 1cf993b6da5..e0b7b72a73b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7450.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7450.json
@@ -1 +1 @@
-{"null": 3.79363972685902}
\ No newline at end of file
+{"null": 0.4335501018639234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7451.json
index f07dd0c3237..aa2ccaace36 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7451.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7451.json
@@ -1 +1 @@
-{"ABRAXANE": 1.6055644585641238, "ADCETRIS": 5.31194250743399, "ADVAGRAF": 2.5709070448682443, "AFINITOR": 1.0724768192627718, "ALEMTUZUMAB": 5.11287239826322, "ALIMTA": 3.4931073339188154, "AMIKACIN": 3.3722477685664174, "ANAKINRA": 4.690349100202264, "ANIDULAFUNGIN": 7.635830207299897, "ANTIBIOTICS": 1.5281375824691834, "ARANESP": 6.611824911750844, "ARIXTRA": 1.821543297993435, "ARZERRA": 10.319379780683096, "ASPARAGINASE": 6.1798630716004, "ATEZOLIZUMAB": 3.70301890065032, "AUTOLOGOUS": 51.48045479911119, "AVASTIN": 2.6183742526814937, "AVELUMAB": 1.9052625286756677, "AXITINIB": 1.0166472385186107, "AZACITIDINE": 6.071747332350092, "AZATHIOPRINE": 3.60898994872856, "BASILIXIMAB": 2.937060749564783, "BEDAQUILINE": 1.631794902629979, "BENLYSTA": 1.517435787872798, "BEVACIZUMAB": 1.961241290983947, "BLINCYTO": 9.684008856701356, "BOCEPREVIR": 2.842931327301222, "BORTEZOMIB": 5.25327860096637, "BOSENTAN": 2.7686972594083707, "BRUKINSA": 2.863726747743638, "BUSILVEX": 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\ No newline at end of file
+{"null": 0.6279266014165759}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7452.json
index 4c2a33c241f..e3da6e88961 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7452.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7452.json
@@ -1 +1 @@
-{"ABILIFY": 18.34742069640324, "null": 1.9234765708495647}
\ No newline at end of file
+{"NPLATE": 116.04096468830942, "null": 0.6720803155154441}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7453.json
index ccbf438e11d..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7453.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7453.json
@@ -1 +1 @@
-{"null": 1.1309260324167865}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7454.json
index 2c0ea5d34d0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7454.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7454.json
@@ -1 +1 @@
-{"BUDESONIDE": 6.395338562829599, "CICLOSPORIN": 7.197126617589531, "CUBICIN": 36.14716161049614, "null": 1.3502238822492725}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7455.json
index ca9b3e1b62d..76afbe42063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7455.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7455.json
@@ -1 +1 @@
-{"ACTRAPID": 1.6536937647599448, "ALEMTUZUMAB": 3.62869809447934, "ALIMTA": 6.783709797899157, "AMIKACIN": 8.943578777579065, "ANAKINRA": 3.497504590144707, "ANIDULAFUNGIN": 22.45631767990235, "APREMILAST": 2.0968844127904083, "ARIXTRA": 6.398672618912167, "ASPARAGINASE": 9.60473461836865, "AVASTIN": 2.023682539787245, "AXICABTAGENE": 8.30347078718364, "AZACITIDINE": 9.87379374040063, "AZATHIOPRINE": 2.544504392466658, "AZTREONAM": 10.637145308357953, "BASILIXIMAB": 4.759676563143698, "BENRALIZUMAB": 5.497043369485493, "BEVACIZUMAB": 2.5083269637545187, "BORTEZOMIB": 4.768354365269039, "BUSILVEX": 21.38006151640097, "BUSULFAN": 8.000990570657361, "BYETTA": 1.2366713481109337, "CAELYX": 1.1776919933181436, "CANCIDAS": 13.71752807117186, "CAPECITABINE": 1.3146861465116322, "CARFILZOMIB": 2.0127512214655607, "CARMUSTINE": 5.833560595534096, "CASPOFUNGIN": 22.75027581385154, "CELECOXIB": 2.082406160609268, "CELLCEPT": 4.472381845577724, "CICLOSPORIN": 4.027269160293017, "CLADRIBINE": 3.044982004551825, "CLOFARABINE": 12.769989342297688, "COAPROVEL": 2.5138671013588394, "COTELLIC": 1.7883587731609636, "CUBICIN": 6.954123828398459, "CYTARABINE": 12.912999659606957, "DAKLINZA": 3.760529087791993, "DAPTOMYCIN": 13.23352250154996, "DARZALEX": 3.717005618366607, "DEFITELIO": 17.19408229592849, "DEXAMETHASONE": 5.612215983418823, "DEXMEDETOMIDINE": 5.164063319775541, "DOCETAXEL": 3.840512063938932, "DOXORUBICIN": 4.488768541598368, "EFIENT": 2.6366679555462884, "EMEND": 4.097623196031904, "EMPAGLIFLOZIN": 2.0493199679513547, "ERBITUX": 2.504274770731291, "EXJADE": 2.3982310973700933, "FIDAXOMICIN": 15.916624274892069, "FILGRASTIM": 2.58453074251702, "FIRDAPSE": 1.8133987052951437, "FORXIGA": 1.7082969673667927, "GANCICLOVIR": 7.811146700237906, "GAZYVARO": 3.751810518334477, "HALAVEN": 3.290143991492804, "HARVONI": 2.443701889236736, "HUMAN": 1.7844278408421426, "IBUPROFEN": 1.0440957007705882, "ICLUSIG": 6.230567785036587, "INCIVO": 4.183588544990558, "INFLIXIMAB": 1.909738811386717, "INVOKANA": 8.617050485520519, "IPILIMUMAB": 1.4625585331570916, "IRINOTECAN": 1.290630401136497, "JAKAVI": 3.595787377626628, "JARDIANCE": 2.9758092744380487, "JEVTANA": 19.48714477896724, "KALETRA": 1.9276564033500332, "KEPPRA": 1.4201881419617068, "KEYTRUDA": 2.7713121369408737, "KYMRIAH": 3.3417569749010974, "KYPROLIS": 4.046336850114739, "LENVIMA": 1.3872212228249996, "LEVETIRACETAM": 1.0026767565047396, "LEVOFLOXACIN": 3.405249312886684, "LIXIANA": 1.37709675705951, "LONSURF": 2.000584116995454, "MABTHERA": 6.096958661345178, "MEKINIST": 1.642978051351342, "MELPHALAN": 7.366596790929221, "METHOTREXATE": 2.51473574896529, "MIDAZOLAM": 1.805326615727196, "MIDOSTAURIN": 10.536515340003334, "MIRCERA": 2.2379664197970053, "MYCOPHENOLATE": 7.377238464992605, "NEULASTA": 2.3741487026266617, "NOVOSEVEN": 8.011561883013968, "NOXAFIL": 4.28646637287122, "NPLATE": 1.4625585331570916, "OBINUTUZUMAB": 4.43836908477213, "ONCASPAR": 3.514681479114153, "OPDIVO": 1.7845282225632433, "OPSUMIT": 1.7686245890530985, "PACLITAXEL": 2.573697234036233, "PEGASYS": 1.8166864612706195, "PEGINTERFERON": 1.7549038184231214, "PEMETREXED": 1.5316117439114725, "POSACONAZOLE": 5.027440280304012, "PRADAXA": 3.2376325429390915, "PRAXBIND": 19.5186778324819, "REMDESIVIR": 15.951058928548616, "REVATIO": 1.2996582629386166, "REVLIMID": 2.863026399981968, "RIBAVIRIN": 1.9818002698523367, "RITUXIMAB": 3.886442055664939, "ROACTEMRA": 6.597440388542451, "RUXOLITINIB": 4.020458857667626, "SOLIRIS": 6.13758482147272, "SOVALDI": 3.187501681052547, "SPRYCEL": 1.0781988878499271, "STELARA": 1.3384912850297817, "TACROLIMUS": 2.38036609686691, "TAMIFLU": 2.096432832703791, "TAXOTERE": 4.0061911267247465, "TELMISARTAN": 1.5771142022512636, "TEMODAL": 2.1913939740298494, "THALIDOMIDE": 2.9667337358143904, "TIGECYCLINE": 8.16353936224208, "TOBRAMYCIN": 6.001593484832365, "TOCILIZUMAB": 5.781739902488358, "TRACLEER": 2.370700903992396, "TRASTUZUMAB": 13.413268875353484, "TRODELVY": 5.297168415788171, "VEKLURY": 3.8146225518168895, "VELCADE": 4.820167045058219, "VENCLYXTO": 6.066469106452171, "VENETOCLAX": 4.587452767872904, "VFEND": 1.6194062816558, "VORICONAZOLE": 3.4798675389559897, "VYXEOS": 10.34632368369127, "XARELTO": 1.977227134742268, "XELODA": 3.3915362479540616, "YERVOY": 1.1447091355198338, "YESCARTA": 5.950482192849383, "YONDELIS": 5.198717897605632}
\ No newline at end of file
+{"ZOSTAVAX": 32.013746867333786, "null": 1.0597142183871304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7456.json
index d5e3f312178..fc1cf6a76b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7456.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7456.json
@@ -1 +1 @@
-{"null": 3.6909512834391984}
\ No newline at end of file
+{"OLANZAPINE": 45.42950352213745, "null": 0.4153167820554171}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7457.json
index e85722bc05a..49a7288faa8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7457.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7457.json
@@ -1 +1 @@
-{"null": 2.946876774685152}
\ No newline at end of file
+{"ABACAVIR": 0.1536367969304868, "AFINITOR": 0.7220415729048217, "ALIMTA": 1.0320785534297672, "AMINOSALICYLIC": 0.3650379779461251, "APIXABAN": 1.038258481065878, "APREPITANT": 1.1562033311394, "ARAVA": 0.0324986662219133, "ARIXTRA": 9.25902644067627, "ATAZANAVIR": 1.4522659636509274, "AVASTIN": 2.05631143636761, "AZATHIOPRINE": 0.396372999034023, "BEVACIZUMAB": 0.7269002934819185, "BLINCYTO": 9.929797071466137, "BORTEZOMIB": 0.7885020641225937, "BRAFTOVI": 2.2811854682211963, "BRILIQUE": 20.42380411221432, "BUDESONIDE": 0.357500259738574, "BUSULFAN": 0.5311995615460297, "CABOMETYX": 0.7820466327242073, "CAPECITABINE": 0.4216520548921197, "CELECOXIB": 1.0032904680562884, "CELLCEPT": 0.7665454263548125, "CHAMPIX": 0.577409672473882, "CICLOSPORIN": 0.6083879056255178, "CLOPIDOGREL": 40.12429531588605, "COAPROVEL": 0.7213433777741187, "COMIRNATY": 0.0436751469179305, "COSENTYX": 0.1381753032384267, "CUBICIN": 0.7283595582661813, "CYMBALTA": 0.2425758349190059, "CYTARABINE": 0.246778688375902, "DEFITELIO": 11.40484520389305, "DEXAMETHASONE": 0.4795930471746252, "DOCETAXEL": 0.5737839073310613, "DULOXETINE": 0.4652917033874782, "DUOPLAVIN": 19.36104701042718, "EFIENT": 21.78118432442854, "ELIQUIS": 12.888955379848, "ENOXAPARIN": 10.117487672013686, "ENTYVIO": 0.3847118889062939, "EXJADE": 1.483729461753527, "EXVIERA": 1.6297793936446427, "FEBUXOSTAT": 2.2259922280989537, "FORSTEO": 0.4026155956776465, "HARVONI": 0.8820879931781342, "IBRANCE": 0.1878569030693147, "IBUPROFEN": 1.864979896079889, "INLYTA": 0.4722858394858571, "INTEGRILIN": 4.657064834481277, "IRESSA": 0.4759642716989912, "ISCOVER": 28.607348225050423, "JAKAVI": 0.7923332379416429, "JANUVIA": 0.5488689204426038, "JARDIANCE": 0.1461955271574299, "JEVTANA": 1.8784297881252952, "KEPPRA": 0.2497243046260195, "KEYTRUDA": 0.4410333702375558, "LANTUS": 0.0751751703494165, "LENVIMA": 1.2547854021109597, "LEVOFLOXACIN": 0.3844200145510938, "LIXIANA": 20.43191077283921, "MEKINIST": 0.5521059417777895, "METHOTREXATE": 0.360043225734471, "NEXAVAR": 5.33247663245497, "OFEV": 0.4678937948966352, "OPDIVO": 0.7716685029108715, "OPSUMIT": 0.5794869830972873, "PANTOPRAZOLE": 0.7180708039088811, "PEGASYS": 0.5747008079197458, "PEGINTRON": 0.554009186150958, "PLAVIX": 28.268636375387345, "PRADAXA": 16.644279443692096, "PRASUGREL": 12.13900453194327, "PRAXBIND": 9.13755565258955, "REBETOL": 1.1397660275468289, "REVATIO": 0.93716524878981, "RIVAROXABAN": 6.963917729964493, "ROACTEMRA": 0.264089758053629, "ROTATEQ": 0.9338157390590512, "RUXOLITINIB": 2.1277394915161216, "SOVALDI": 1.3193902401199646, "SPIKEVAX": 0.0336277461424678, "SPIRONOLACTONE": 1.6449776913925829, "SPRYCEL": 1.3037268346560962, "STELARA": 0.1911324900575784, "STIVARGA": 2.8155030696838548, "SUTENT": 0.9203858702410568, "TAMIFLU": 3.9500319974423648, "TICAGRELOR": 59.43068126127158, "TORISEL": 1.2404414266827353, "TOZINAMERAN": 0.0336266541792842, "TRACLEER": 0.3518202689087643, "VAXZEVRIA": 0.0342661619734724, "VOTRIENT": 0.8020923070879765, "XARELTO": 9.830170024322836, "XELJANZ": 0.141104489283181, "XTANDI": 0.2241257570602356, "ZOSTAVAX": 0.1536905405921845, "null": 1.558140229594847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7458.json
index 82e33128ca5..492ec3be330 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7458.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7458.json
@@ -1 +1 @@
-{"TRUVADA": 31.856959587365715}
\ No newline at end of file
+{"BRAFTOVI": 30.444162681138355, "CIALIS": 55.802230110504254, "COMIRNATY": 0.2169820310204508, "COSENTYX": 6.9560838572629065, "ELIQUIS": 1.2777919285313866, "ENBREL": 5.274682234066263, "GARDASIL": 2.052637310544196, "MEKINIST": 6.214755350681995, "PEGASYS": 1.2444027046616473, "ROACTEMRA": 4.603002156552246, "SIMPONI": 5.802748229277251, "SPIKEVAX": 0.1014142126787757, "SUTENT": 0.7698022230045423, "VAXZEVRIA": 0.0889530479021087, "XELJANZ": 1.529406949260032, "ZELBORAF": 61.79864680335034, "ZOSTAVAX": 10.7359936937321, "null": 0.8997323258159352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7459.json
index 9a35f8f458e..98dbeadb68b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7459.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7459.json
@@ -1 +1 @@
-{"ABATACEPT": 7.116980147053906, "ADALIMUMAB": 2.287553969472409, "AMINOSALICYLIC": 30.847126119186527, "ARAVA": 7.056097733713079, "COSENTYX": 19.946554934259595, "HUMIRA": 15.34781210291506, "JANUVIA": 34.66076063786128, "KEYTRUDA": 3.897667219372453, "LEFLUNOMIDE": 41.29968506120468}
\ No newline at end of file
+{"null": 0.8132120548405579}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/746.json
index 8820ffc77d0..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/746.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/746.json
@@ -1 +1 @@
-{"ELIQUIS": 5.380549696214997, "MICARDIS": 55.166066792057, "ZOSTAVAX": 33.04466134141133, "null": 1.1194450070441693}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7460.json
index ec5160650e3..d8bc6530cd4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7460.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7460.json
@@ -1 +1 @@
-{"ABILIFY": 3.057834389864757, "AIMOVIG": 1.450928220484465, "ARIPIPRAZOLE": 8.620531324107283, "AZILECT": 11.671185138329973, "BRINTELLIX": 17.840530724195492, "BUPRENORPHINE": 3.970031472505516, "CANNABIDIOL": 6.00236011520579, "CARBIDOPA": 4.394180012137349, "CELECOXIB": 3.2729065572249314, "COMTAN": 3.4868355968211087, "CYMBALTA": 18.65622994284165, "DULOXETINE": 31.358569084377606, "ESOMEPRAZOLE": 34.30555816168346, "FENTANYL": 10.94243491644446, "IBUPROFEN": 3.994458242259347, "LACOSAMIDE": 1.4082403946261923, "LATUDA": 2.6108654168673247, "LURASIDONE": 34.98809190421349, "LYRICA": 1.0612873470379751, "MELATONIN": 1.943810206556932, "METHYLTHIONINIUM": 224.85939299049392, "MIDAZOLAM": 2.819100199761688, "NOT": 3.847451254053208, "OLANZAPINE": 8.54553092411087, "PANTOPRAZOLE": 1.060279760250621, "PREGABALIN": 1.0017420983998, "RISPERIDONE": 8.687994599418479, "STALEVO": 2.6394945306584607, "SUBOXONE": 1.1290869639550516, "VALDOXAN": 16.484636612791757, "VORTIOXETINE": 31.178105101448192, "ZYPREXA": 3.1322252258774474, "null": 4.175173704204188}
\ No newline at end of file
+{"CIALIS": 467.9892252687633, "DABRAFENIB": 101.38713681701633, "IPILIMUMAB": 40.76271445567616, "KEYTRUDA": 19.44133504356189, "MEKINIST": 153.1431817580438, "null": 0.1057153326863489}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7461.json
index 0cf7ab172cb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7461.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7461.json
@@ -1 +1 @@
-{"CAELYX": 699.3842590766859}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7462.json
index bd578dac719..f9a620b2fea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7462.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7462.json
@@ -1 +1 @@
-{"BINIMETINIB": 313.3136554751918, "BRAFTOVI": 1164.8285590885182, "COTELLIC": 107.21847583932563, "EYLEA": 44.76182689470113, "MEKINIST": 37.03445642689844}
\ No newline at end of file
+{"null": 3.415430155154916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7463.json
index b3d141cbd1a..3f9d9cd048c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7463.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7463.json
@@ -1 +1 @@
-{"BRAFTOVI": 1040.8470898482908, "COTELLIC": 409.36206245802754}
\ No newline at end of file
+{"RIBOCICLIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7464.json
index ba35762f5b7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7464.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7464.json
@@ -1 +1 @@
-{"null": 9.224438259435836}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7465.json
index 69f43dec47a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7465.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7465.json
@@ -1 +1 @@
-{"null": 5.778443613463153}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7466.json
index 51ac5cf31ec..4ae069cbc40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7466.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7466.json
@@ -1 +1 @@
-{"null": 1.3304386503414245}
\ No newline at end of file
+{"ABACAVIR": 0.2912394821558792, "ABATACEPT": 1.892353452882512, "ABILIFY": 3.132792460533706, "ACE": 5.312704066005202, "ACTOS": 0.8681400268215164, "ADALIMUMAB": 0.6178661148634954, "ADCIRCA": 1.1607455286732558, "ADEMPAS": 0.6486554399462315, "AFINITOR": 0.2193313873422513, "AIMOVIG": 6.2439179451646005, "ALEMTUZUMAB": 0.4729419694634552, "AMBRISENTAN": 2.550416963317032, "AMINOSALICYLIC": 0.4580798703027043, "ANAKINRA": 0.2772479069564464, "ANTIBIOTICS": 2.291643309185935, "APIDRA": 0.6703256382217374, "APIXABAN": 3.0909539706047227, "APREMILAST": 3.471302949247177, "APROVEL": 0.4468623980631679, "ARANESP": 0.2147126374931443, "ARAVA": 0.2857306663772257, "ARIPIPRAZOLE": 1.1347568470427565, "ATAZANAVIR": 0.5030324938443381, "ATRIPLA": 0.1157700425154849, "AUBAGIO": 3.968119455313777, "AVAMYS": 1.553465631068672, "AVANDIA": 0.2420736232099261, "AVASTIN": 0.208460992507425, "AVONEX": 2.875625414103976, "AZATHIOPRINE": 0.4725798001111777, "AZILECT": 1.9693778359268224, "BENLYSTA": 1.496668844976453, "BETAFERON": 1.0097081371701282, "BETMIGA": 0.532163333822603, "BIKTARVY": 0.6146056554891913, "BOSULIF": 1.5269239454278023, "BRAFTOVI": 0.8169221709421546, "BRILIQUE": 0.3927950045892956, "BRINTELLIX": 1.019919782714556, "BRIVARACETAM": 6.0700529536339065, "BRIVIACT": 2.874098043810729, "BUDESONIDE": 0.1616414580535924, "BUPIVACAINE": 1.148768827657242, "BUPRENORPHINE": 1.2339874321400413, "BYDUREON": 1.4969229907631612, "BYETTA": 0.8348812734855864, "CABOMETYX": 0.5533599652661083, "CAPECITABINE": 0.2002979884165398, "CELECOXIB": 0.8148113831763675, "CELLCEPT": 0.4683522941123636, "CHAMPIX": 2.9491196392023493, "CICLOSPORIN": 0.1871396696014517, "CIMZIA": 0.3353693886924475, "CLOPIDOGREL": 0.2048103486226586, "COMBIVIR": 1.1020985967961126, "COMIRNATY": 0.750142070358743, "COMTAN": 0.8802158754672282, "COSENTYX": 0.8725779453403786, "CYMBALTA": 2.846830971216596, "DAKLINZA": 1.2673151606101074, "DARZALEX": 0.3507560742478752, "DEXAMETHASONE": 0.4763454073735008, 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0.4566048980776169, "XTANDI": 3.0024892426353595, "XYREM": 3.484801502040036, "YESCARTA": 2.343798909178276, "ZOSTAVAX": 0.434209438240865, "ZYPADHERA": 1.0547316501059112, "ZYPREXA": 1.163698068475805, "null": 1.288564897144589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7467.json
index b125ccc462e..18120a1205f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7467.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7467.json
@@ -1 +1 @@
-{"BUSILVEX": 2701.909723011382, "null": 1.1605127259847858}
\ No newline at end of file
+{"COMIRNATY": 11.297940715816235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7468.json
index 0978ae546bf..d0f2ff5e762 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7468.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7468.json
@@ -1 +1 @@
-{"null": 1.1364325208437909}
\ No newline at end of file
+{"ACLIDINIUM": 34.264617464400864, "COMIRNATY": 1.6247499130780254, "KEPPRA": 1.6497400149917802, "PEGASYS": 0.9529602173652176, "SPIKEVAX": 1.1843208255293365, "TOZINAMERAN": 1.7900452868384895, "VAXZEVRIA": 0.6372353704898747, "ZOSTAVAX": 4.372445840180193, "null": 0.8352084946580907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7469.json
index fbe1c84582f..f5072b39039 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7469.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7469.json
@@ -1 +1 @@
-{"EXJADE": 172.005066865985}
\ No newline at end of file
+{"COMIRNATY": 0.2577309163660375, "PRIVIGEN": 51.809006245977095, "null": 1.2742837001990306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/747.json
index 4bb5b347ae5..35f0403e933 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/747.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/747.json
@@ -1 +1 @@
-{"ABILIFY": 24.360455772253943, "BUSULFAN": 9.992748364049136, "CYMBALTA": 2.92058461999618, "KEPPRA": 3.1631709644460155, "LEVETIRACETAM": 7.871720056272367, "OPTIMARK": 6.205003088637609, "null": 1.2798084506064151}
\ No newline at end of file
+{"ANAKINRA": 10.215690169036352, "COMIRNATY": 0.613501213255778, "KALETRA": 16.355469582221016, "PEGINTRON": 4.091608767835779, "SPIKEVAX": 0.4062332033063415, "TOZINAMERAN": 1.1797813814332514, "VAXZEVRIA": 0.2314684030342546, "null": 2.4154000166692837}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7470.json
index 840872668f0..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7470.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7470.json
@@ -1 +1 @@
-{"ADCIRCA": 30.863988873807475, "ARAVA": 1.5545542463086706, "CICLOSPORIN": 2.918959635759406, "CYMBALTA": 1.6395029370998406, "EXJADE": 19.863293033834637, "GARDASIL": 3.985084809183125, "SIMPONI": 3.480895365711731, "TOZINAMERAN": 1.108730120690078, "XELJANZ": 4.377714024717936}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7471.json
index 04e96f36bb2..3c9d34482bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7471.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7471.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 3.024994164257086, "ANAKINRA": 9.350318386341488, "ARANESP": 4.796041499913586, "AZACITIDINE": 13.399058781761836, "CICLOSPORIN": 6.538480860612826, "CYTARABINE": 3.108025899253904, "DEXAMETHASONE": 1.1676510590091056, "ENTRESTO": 1.336392817955802, "EXJADE": 199.9848377044482, "HUMIRA": 1.3933462060007735, "JAKAVI": 6.740696760701432, "KYMRIAH": 65.39416401357049, "LEVETIRACETAM": 2.4478264342617595, "MIRCERA": 12.76199881401562, "PEGASYS": 3.3735598977719947, "PEGINTERFERON": 4.434013604529469, "PEGINTRON": 2.072456724900973, "SOLIRIS": 9.984120278895205, "STELARA": 1.1290610357649222, "YESCARTA": 9.292896250720664}
\ No newline at end of file
+{"COMIRNATY": 0.2072806233153117, "KEPPRA": 5.427607651767358, "LANTUS": 1.1273756736999203, "NUTROPIN": 137.41681124373372, "SOMATROPIN": 56.60556288884906, "STELARA": 2.6667742620402257, "XOLAIR": 1.8700445815549347, "ZOSTAVAX": 1.8584000651773749, "null": 3.152989915384868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7472.json
index 215369fa141..e346e9fd882 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7472.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7472.json
@@ -1 +1 @@
-{"null": 2.0384881070613017}
\ No newline at end of file
+{"null": 1.7686867308074297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7473.json
index 48aa572029a..51ec3c069d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7473.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7473.json
@@ -1 +1 @@
-{"null": 2.967043443635618}
\ No newline at end of file
+{"CICLOSPORIN": 2.362712968566944, "COMIRNATY": 1.0110082515055807, "GARDASIL": 5.627798572035309, "MMRVAXPRO": 3.955422373628032, "NIMENRIX": 16.035210660767962, "PRIVIGEN": 43.20889455758225, "SPIKEVAX": 0.49431497977572, "VAXZEVRIA": 0.9685429380208558, "null": 1.416216434378884}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7474.json
index 4b572f4837c..a9a99d578aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7474.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7474.json
@@ -1 +1 @@
-{"CELLCEPT": 5.164591760727684, "CICLOSPORIN": 1.343880820539049, "CIMZIA": 4.068640380530852, "FASENRA": 11.955447439779324, "GARDASIL": 3.4222455352845254, "PLAVIX": 2.773883560134318, "RIXATHON": 108.53942842560888, "XOLAIR": 25.031819764707457, "null": 2.8972038031510987}
\ No newline at end of file
+{"AMINOSALICYLIC": 3.650332361743743, "ARAVA": 0.2223878003287965, "AZACITIDINE": 11.329537963438954, "BENLYSTA": 2.146702973141024, "BEXSERO": 12.064029398691202, "BUMETANIDE": 24.377082120436363, "CELLCEPT": 2.1248435762577955, "CICLOSPORIN": 0.9523569801707102, "CIMZIA": 2.3079102876524717, "COMIRNATY": 0.3973430301746652, "CYTARABINE": 1.802007344160923, "DEXAMETHASONE": 2.8292814851214185, "ELIQUIS": 0.3162192251019017, "ENBREL": 1.127066281207775, "GARDASIL": 1.920125085633452, "HIZENTRA": 4.400028384221042, "HUMAN": 3.0682541172442934, "INFANRIX": 12.069120941351851, "IPILIMUMAB": 3.548983673908793, "IRON": 8.771872798563658, "KEPPRA": 1.342514006234182, "KEYTRUDA": 4.86887302980892, "KIOVIG": 12.883176172319638, "MEKINIST": 2.3230488546159225, "METHOTREXATE": 1.9336365502640112, "NIMENRIX": 3.128265998765871, "OPDIVO": 4.957867972420475, "PEGASYS": 0.9406547357271676, "PEGINTERFERON": 1.8870471760691736, "PEGINTRON": 1.218573333151925, "PRIVIGEN": 6.603147610579945, "RINVOQ": 3.781622176954624, "RITUXIMAB": 1.986018103260481, "ROACTEMRA": 2.9901200779088395, "ROTATEQ": 3.6612257708683407, "SIMPONI": 0.8298661544571854, "SOLIRIS": 6.48169470954232, "SPIKEVAX": 0.3485216802206112, "SPINRAZA": 10.622511670869004, "STELARA": 1.4865641954600484, "TAMIFLU": 2.1985142309196237, "TOZINAMERAN": 0.5954309119436216, "TWINRIX": 5.9297707516085385, "VAXZEVRIA": 0.2261125675587769, "VFEND": 2.337675901633092, "XELJANZ": 1.308666647080082, "XOLAIR": 0.8481662271986808, "YERVOY": 6.01690293636279, "ZOSTAVAX": 0.6647330334376882, "null": 1.144168330900681}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7475.json
index ddd1a470bb2..6f21e394bd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7475.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7475.json
@@ -1 +1 @@
-{"XOLAIR": 10.77172523023931, "null": 4.630565987304372}
\ No newline at end of file
+{"BRAFTOVI": 3.761054922071707, "CELLCEPT": 1.4004444123612891, "COMIRNATY": 0.2320989418437825, "FLEBOGAMMA": 110.00785822130943, "GARDASIL": 0.6072498602478117, "HIZENTRA": 41.97906138911333, "HUMAN": 101.84303491415676, "HYQVIA": 39.70174060372521, "IPILIMUMAB": 8.047001915998338, "KEYTRUDA": 2.4619659063791017, "KIOVIG": 120.66271390629689, "MEKINIST": 1.5960700696429635, "OPDIVO": 9.269458446645515, "PRIVIGEN": 180.84566839423408, "SIMPONI": 0.9747417173907824, "SPIKEVAX": 0.1661489644564156, "SPINRAZA": 15.887930131253365, "TELMISARTAN": 12.6570295587455, "TOZINAMERAN": 0.2046246267669291, "VAXZEVRIA": 0.0516047035524376, "null": 1.5457274044990268}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7476.json
index 8fea4d7e791..32b19381bfe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7476.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7476.json
@@ -1 +1 @@
-{"VAXZEVRIA": 31.205225252261773}
\ No newline at end of file
+{"AMINOSALICYLIC": 12.982161620973324, "COMIRNATY": 0.1496427892135316, "FENTANYL": 4.973503066904578, "KEPPRA": 3.8917112871652857, "MELPHALAN": 54.39845061524957, "PEGINTRON": 3.074499234801986, "RELVAR": 78.1304303029806, "SPINRAZA": 40.26448965100187, "null": 0.771647768538743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7477.json
index 88b26039d33..cf426f3603f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7477.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7477.json
@@ -1 +1 @@
-{"CRESEMBA": 2531.003005491023}
\ No newline at end of file
+{"SPINRAZA": 162.41417442634565, "null": 2.2154053164723506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7478.json
index 54c64bbc1ba..a8485d0db7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7478.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7478.json
@@ -1 +1 @@
-{"null": 1.1228291695147434}
\ No newline at end of file
+{"ATAZANAVIR": 24.840327310770174, "BIKTARVY": 22.12526967402916, "CELLCEPT": 18.569423336747462, "CICLOSPORIN": 7.010885415783273, "DEXAMETHASONE": 7.80655424882417, "EFAVIRENZ": 94.03975606283969, "EMTRICITABINE": 57.65008032027289, "KALETRA": 16.868686392114117, "LAMIVUDINE": 108.48959861935464, "null": 0.2325382872248292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7479.json
index 78647b0c076..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7479.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7479.json
@@ -1 +1 @@
-{"null": 3.3106508746180974}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/748.json
index f22f76a6a14..3982c4303f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/748.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/748.json
@@ -1 +1 @@
-{"ABILIFY": 2.071235623122248, "ARIPIPRAZOLE": 2.7461827916883035, "AVAMYS": 2.84365553507557, "BUPRENORPHINE": 3.0347779519353497, "COMBIVIR": 3.8574475549439966, "CYMBALTA": 1.0104671348266312, "FENTANYL": 1.4409429550060469, "GARDASIL": 4.851267571153799, "INFANRIX": 11.203989528457498, "KAFTRIO": 10.769078587062983, "KEPPRA": 3.677042260618155, "LEVETIRACETAM": 5.210961635223912, "SUBOXONE": 5.869074442857228, "ZOSTAVAX": 1.0287400912556188, "null": 4.559624596490248}
\ No newline at end of file
+{"null": 0.6842411932383017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7480.json
index 3a83d9a006f..199d6e42991 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7480.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7480.json
@@ -1 +1 @@
-{"VIAGRA": 73.16288561020968, "null": 2.3277973666180256}
\ No newline at end of file
+{"COMIRNATY": 0.7932524332543266}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7481.json
index b2a3f9b575d..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7481.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7481.json
@@ -1 +1 @@
-{"null": 1.7555432159887274}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7482.json
index 3eb1fc38f58..c4ea2407f67 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7482.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7482.json
@@ -1 +1 @@
-{"ABILIFY": 53.201182762049015, "ARIPIPRAZOLE": 10.466426764176166, "AUBAGIO": 2.360359871291432, "BRINTELLIX": 28.57218725136006, "COAPROVEL": 3.476057189132695, "CYMBALTA": 2.575726776579052, "DULOXETINE": 5.6430888393973415, "LEVETIRACETAM": 1.6105730379191718, "OLANZAPINE": 2.7635160233447804, "VIAGRA": 2.252570829932949, "VORTIOXETINE": 41.61842060244262, "ZYPREXA": 3.001530121166997, "null": 4.219860469532605}
\ No newline at end of file
+{"LEMTRADA": 143.58795662770856, "null": 0.158860124038122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7483.json
index d4c56fded2a..0794cb7a590 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7483.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7483.json
@@ -1 +1 @@
-{"null": 3.363071307471851}
\ No newline at end of file
+{"AZATHIOPRINE": 58.24548228299174, "MENVEO": 135.67257430230964, "SOLIRIS": 111.47147675039942, "null": 1.651722718256705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7484.json
index 61930c773db..030666f2ec4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7484.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7484.json
@@ -1 +1 @@
-{"OLANZAPINE": 26.616447736462533, "null": 1.612647142089502}
\ No newline at end of file
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7485.json
index 0b11f69456b..8b614478289 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7485.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7485.json
@@ -1 +1 @@
-{"null": 1.0375289796092422}
\ No newline at end of file
+{"null": 0.5538116827786236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7486.json
index 6d55750d5d7..c7a767ccc0f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7486.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7486.json
@@ -1 +1 @@
-{"null": 2.739337169947462}
\ No newline at end of file
+{"ALEMTUZUMAB": 84.33319836427455, "AMINOSALICYLIC": 75.855969798588, "BEDAQUILINE": 71.92468919821913, "BUSULFAN": 22.102761670448864, "CICLOSPORIN": 7.085756019770538, "COMBIVIR": 29.838379456352666, "DEXAMETHASONE": 26.504696738189164, "EFAVIRENZ": 48.183797260451534, "FILGRASTIM": 94.97647903946046, "null": 0.2946145496044023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7487.json
index f0f469499ca..a655460aea0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7487.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7487.json
@@ -1 +1 @@
-{"null": 1.4912809900639403}
\ No newline at end of file
+{"ABACAVIR": 7.782808416034403, "ALEMTUZUMAB": 18.80294904643249, "CELLCEPT": 7.470317039049253, "CIMZIA": 1.8080259674836767, "COMIRNATY": 0.4542040581877848, "GARDASIL": 3.2392127816267102, "INTEGRILIN": 96.46591368346768, "PEGASYS": 2.343774189009945, "SPIKEVAX": 0.355831123149486, "TOZINAMERAN": 0.8546440377724172, "VAXZEVRIA": 0.3243860414086612, "null": 0.7501101395735622}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7488.json
index d0c1ff2d9cf..79e9a830619 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7488.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7488.json
@@ -1 +1 @@
-{"AERIUS": 1.500877265275789, "ALIMTA": 1.001752845739491, "AMIKACIN": 4.433847037674333, "APROVEL": 4.864712114951386, "AVASTIN": 3.069680801595763, "AZATHIOPRINE": 3.114413123063571, "AZTREONAM": 11.323559073794, "BEDAQUILINE": 1.7154940350666184, "BORTEZOMIB": 3.456845078529644, "BRIDION": 5.306605193289111, "BUPIVACAINE": 1.603274990760637, "CLOPIDOGREL": 1.1234812211203724, "CUBICIN": 1.4681966270758615, "CYTARABINE": 2.0512098708896658, "DEXAMETHASONE": 2.4498908774641093, "ENOXAPARIN": 2.362132501261065, "ENTRESTO": 1.0321417372198145, "EPIVIR": 2.4972995614281515, "ESOMEPRAZOLE": 1.22970723285849, "EUCREAS": 3.8966614155691, "FENTANYL": 1.721028880671137, "FORXIGA": 1.4447276588430162, "GANCICLOVIR": 4.025557232934711, "GLUCAGON": 16.698931492150127, "HERCEPTIN": 1.2720201975519014, "HYDROCORTISONE": 1.7593543035435042, "IBUPROFEN": 4.626736044374078, "ICLUSIG": 1.4738767879147052, "INTEGRILIN": 6.224400534317862, "IRBESARTAN": 2.259259824064036, "ISENTRESS": 2.222111338120247, "JAKAVI": 1.81548624883157, "JEVTANA": 4.774154670816518, "LACOSAMIDE": 1.123387340593603, "LEVOFLOXACIN": 1.4542493693809606, "METFORMIN": 3.327023834886204, "MICARDIS": 2.623139078968608, "MIDAZOLAM": 1.934118956349821, "MIRCERA": 2.314983719551967, "NOT": 1.2771450624337377, "NOVOSEVEN": 4.882720249727275, "ONCASPAR": 6.7401354049871465, "OPDIVO": 1.4374921465327626, "PIOGLITAZONE": 12.637787872803091, "PLAVIX": 1.261496993448188, "PRADAXA": 4.418301622348394, "PRAXBIND": 9.637777716063638, "PREGABALIN": 1.2319436632201604, "PRIVIGEN": 1.2813345674849497, "PROPRANOLOL": 4.230459410069172, "RASILEZ": 1.9543978992745843, "REMDESIVIR": 9.061589255036733, "ROTATEQ": 1.415530130019834, "SAMSCA": 7.025387275642692, "SPINRAZA": 1.073600754250843, "SUFENTANIL": 22.7803855869522, "SYNAGIS": 1.4332634301950973, "TAMIFLU": 4.262421730175169, "TELMISARTAN": 3.060508605316859, "TRACLEER": 1.0557986064264573, "VFEND": 1.5816219203647568, "null": 3.461147074669838}
\ No newline at end of file
+{"null": 3.224167334879223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7489.json
index d818552fa99..cd7013a3041 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7489.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7489.json
@@ -1 +1 @@
-{"ADENURIC": 11.700086132993825, "APREMILAST": 6.352401593648557, "ARIXTRA": 55.90311496897804, "AVASTIN": 2.363712040246158, "BASILIXIMAB": 6.822520705231788, "BEDAQUILINE": 2.864585034751503, "BRILIQUE": 13.528784758742788, "BUDESONIDE": 2.088468596141406, "BUSULFAN": 3.6374516851319503, "CELLCEPT": 1.2537745117306431, "CLOPIDOGREL": 15.448649536824144, "DEXAMETHASONE": 1.0046861883474305, "EFIENT": 34.962023022569696, "ELIQUIS": 11.31341028150465, "ENOXAPARIN": 23.631444096834187, "IBUPROFEN": 2.2720273099398463, "LIXIANA": 10.4689188616605, "MACITENTAN": 19.20432157929326, "NEXAVAR": 1.4957305916215144, "NOVOSEVEN": 48.33520035500083, "PANTOPRAZOLE": 2.5752072038580494, "PLAVIX": 19.310729220045054, "PRADAXA": 27.35712337530486, "PRASUGREL": 35.73287990223736, "PRAXBIND": 42.25465395635633, "SOLIRIS": 1.218079524064312, "SUFENTANIL": 4.612095962920212, "TICAGRELOR": 8.554998460301464, "XARELTO": 20.1780348326518, "null": 1.8156074904832948}
\ No newline at end of file
+{"BEXSERO": 445.5767647044845, "SOLIRIS": 207.6172862137629, "null": 0.308562274080619}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/749.json
index ba2613ad196..c8718172ed1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/749.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/749.json
@@ -1 +1 @@
-{"null": 1.2229875075149683}
\ No newline at end of file
+{"null": 0.836747143117295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7490.json
index 4b094a8325b..526ddc4cd7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7490.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7490.json
@@ -1 +1 @@
-{"ACTRAPHANE": 779.2051217499967, "ACTRAPID": 342.5580365368121, "APIDRA": 20.10688559038641, "HUMALOG": 31.95233324724992, "INSULIN": 11.428123004264917, "INSUMAN": 565.3150908164297, "LANTUS": 20.4753558819406, "LEVEMIR": 11.670328721241091, "NOVORAPID": 11.988244192051583, "null": 1.0345588132000552}
\ No newline at end of file
+{"SOLIRIS": 242.53582199273248, "null": 1.6299751006795478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7491.json
index c030ed77b21..5725d081402 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7491.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7491.json
@@ -1 +1 @@
-{"null": 4.379498629510223}
\ No newline at end of file
+{"MENVEO": 232.4328799216312, "SOLIRIS": 335.03516497457986, "null": 0.6907135691398874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7492.json
index 23b055efad1..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7492.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7492.json
@@ -1 +1 @@
-{"null": 3.77657001277882}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7493.json
index 246b25d2e0b..ef27ca3f643 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7493.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7493.json
@@ -1 +1 @@
-{"null": 2.05052867485809}
\ No newline at end of file
+{"null": 0.4502336298824811}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7494.json
index a65d08e65eb..5443a5f290b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7494.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7494.json
@@ -1 +1 @@
-{"THIOTEPA": 605.5471836042957, "null": 1.7217393479537917}
\ No newline at end of file
+{"COMBIVIR": 53.79285941713882, "null": 4.765369297894689}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7495.json
index c07eddf3c56..e068679d16d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7495.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7495.json
@@ -1 +1 @@
-{"STELARA": 22.62745626190997}
\ No newline at end of file
+{"COMIRNATY": 1.0410732086561902, "null": 0.3568059494881493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7496.json
index 15fcdfcb700..4ac610eaf50 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7496.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7496.json
@@ -1 +1 @@
-{"ACETYLSALICYLIC": 383.6489020464991, "ANAKINRA": 115.23191269231651, "ARAVA": 4.2930570824520204, "ATRIPLA": 5.263334162118969, "CIMZIA": 2.951268166059623, "ENBREL": 12.7797024153782, "JARDIANCE": 2.758386087465418, "LANTUS": 2.6598471128970176, "SIMPONI": 7.881198650214441, "TRUVADA": 3.618436779042909, "XELJANZ": 6.910809620132806, "ZOSTAVAX": 7.058523283133602}
\ No newline at end of file
+{"ELIQUIS": 10.414035348475696, "PLAVIX": 20.746434550939004, "null": 0.9326039137351791}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7497.json
index 1edc3f34573..5e728e203cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7497.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7497.json
@@ -1 +1 @@
-{"ATRIPLA": 10.35315155808041, "AVANDIA": 1.4032932368651445, "ELIQUIS": 1.7935389046068526, "EVISTA": 6.6465963699851, "FORSTEO": 9.222699851601687, "HUMALOG": 5.059821612431992, "IBRANCE": 2.381525583225077, "INSULIN": 2.421806964992624, "KALETRA": 3.127279308569782, "LANTUS": 3.490140314836656, "STELARA": 1.43291214158178, "STRIBILD": 7.770960339319937, "SUBOXONE": 2.1392611528795573, "TRUVADA": 9.612681412791336, "XELJANZ": 5.785637192367399, "XTANDI": 3.944255454997076}
\ No newline at end of file
+{"ARAVA": 0.5513033824859331, "ATRIPLA": 1.023945543194002, "CIMZIA": 1.0272777500753896, "COMIRNATY": 0.1071336381612706, "COSENTYX": 4.473172173323087, "CYMBALTA": 1.0437959975742064, "ELIQUIS": 2.5972627404396804, "ENTRESTO": 2.832516971038215, "HUMALOG": 2.413168073626464, "LANTUS": 1.551757387628731, "LEVOFLOXACIN": 2.3093975223741285, "OZEMPIC": 62.42886835829968, "PEGASYS": 1.431685268360572, "SIMPONI": 3.195123604768693, "STELARA": 1.76262529123164, "STRIBILD": 2.8838998318480638, "TOZINAMERAN": 0.2581005175180981, "TRUVADA": 1.0257513898691, "VIAGRA": 4.307880722785227, "XELJANZ": 5.2741619663013655, "ZOSTAVAX": 4.731406102885518, "null": 1.4635097976730087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7498.json
index 6c506ad951b..7b6d104d860 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7498.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7498.json
@@ -1 +1 @@
-{"COMIRNATY": 3.866225327317989, "COVID19": 3.5282621207683795, "SPIKEVAX": 2.004488703120628, "TOZINAMERAN": 4.459749573229168, "VAXZEVRIA": 2.180484506073059}
\ No newline at end of file
+{"null": 0.7254051087831385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7499.json
index ac9f96f85f4..74709c26f85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7499.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7499.json
@@ -1 +1 @@
-{"ARAVA": 1.1400830045005312, "BENLYSTA": 6.981500190706231, "CIMZIA": 3.1327384456900718, "HUMIRA": 6.222094698634703, "JARDIANCE": 2.47162077925628, "LANTUS": 4.958150420739237, "SIMPONI": 14.517138607867851, "STELARA": 4.379247601871551, "XELJANZ": 7.963545249038041, "ZOSTAVAX": 11.695241199809098, "null": 1.2408143345190168}
\ No newline at end of file
+{"COMIRNATY": 14.547537104916428, "ESMYA": 15.82191013257609, "MODERNA": 16.838608953042066, "SPIKEVAX": 2.3831760073212056, "TOZINAMERAN": 0.2519507955068807, "VAXZEVRIA": 0.2008854920357642, "null": 0.1107387551449093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/75.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/75.json
index f2538a3ff55..07d0e87123d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/75.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/75.json
@@ -1 +1 @@
-{"null": 8.254122559732778}
\ No newline at end of file
+{"CIMZIA": 2.237641744302947, "COMBIVIR": 15.92037670770376, "COMIRNATY": 0.9180046341015268, "GARDASIL": 3.5810030082947564, "KEPPRA": 2.200371953678508, "SPIKEVAX": 0.2928639383900503, "TAMIFLU": 5.87576722310144, "TOZINAMERAN": 0.7501383697557586, "VAXZEVRIA": 0.1128302094394068, "null": 1.7218048219264046}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/750.json
index bca5cf9253c..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/750.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/750.json
@@ -1 +1 @@
-{"BONVIVA": 957.3265170684526, "EVENITY": 213.41435445724005}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7500.json
index d1bfb7b5400..621b105b0b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7500.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7500.json
@@ -1 +1 @@
-{"null": 1.4193475023715}
\ No newline at end of file
+{"COMIRNATY": 1.0480888795899983, "null": 0.4175806272323522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7501.json
index 03b778baaf1..a6badc173c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7501.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7501.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"AIMOVIG": 3.506061082804624, "ALLI": 173.7794336599358, "BIKTARVY": 30.25483376445725, "COMIRNATY": 1.7592028568989075, "CYMBALTA": 0.767015562767463, "IBRANCE": 1.257636412179479, "SPIKEVAX": 1.0083939887288438, "TOZINAMERAN": 0.6743192645408497, "VAXZEVRIA": 0.657095898577337, "ZOSTAVAX": 5.3132800694875, "null": 1.3262199695033308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7502.json
index 6fea0296c55..8fcf35ecf32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7502.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7502.json
@@ -1 +1 @@
-{"CYTARABINE": 9.264159808038096, "KEYTRUDA": 6.638637429754011, "OPDIVO": 10.437767186324118, "ZOSTAVAX": 6.969878833291585}
\ No newline at end of file
+{"ABILIFY": 4.852736196406471, "AIMOVIG": 3.4657347503866305, "CIMZIA": 6.38221926166177, "COMIRNATY": 1.224521001502743, "FASLODEX": 7.282248005737272, "SPIKEVAX": 0.7017453245449639, "TOZINAMERAN": 3.077222925548081, "VAXZEVRIA": 0.8661114851682298, "ZOSTAVAX": 7.220952971096476, "null": 0.5460389861623807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7503.json
index 7ddfcdad6e4..89ae6b632d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7503.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7503.json
@@ -1 +1 @@
-{"COMIRNATY": 9.59012983394286, "SPIKEVAX": 3.492837131445471}
\ No newline at end of file
+{"COMIRNATY": 2.6027241667558285, "null": 0.6842411932383017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7504.json
index 4bd7e9c1b58..c75b6e144bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7504.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7504.json
@@ -1 +1 @@
-{"EXJADE": 60.007410891245776}
\ No newline at end of file
+{"COMIRNATY": 16.856569673952173, "SPIKEVAX": 2.451935947999842, "VAXZEVRIA": 0.3679903529526846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7505.json
index 7235a57f3c6..f5725037249 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7505.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7505.json
@@ -1 +1 @@
-{"ADEMPAS": 15.43620096209162, "EXJADE": 1974.8523594569065, "OXBRYTA": 1255.2332632313437}
\ No newline at end of file
+{"COMIRNATY": 20.23697553800946, "SPIKEVAX": 2.691128157365338, "TOZINAMERAN": 0.4334323177141654, "VAXZEVRIA": 0.2756874128566216, "null": 0.0169771322317194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7506.json
index c6a3f91d950..f0d4ca87a87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7506.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7506.json
@@ -1 +1 @@
-{"EXJADE": 295.2599808711}
\ No newline at end of file
+{"AIMOVIG": 0.6073263727483459, "AUBAGIO": 0.1482894797909514, "BRINTELLIX": 0.3049359209301803, "CHAMPIX": 0.0886679369218373, "CIMZIA": 0.0578469284331139, "COMIRNATY": 15.178784099622598, "CYMBALTA": 0.0267036173299866, "ELIQUIS": 0.0241550627777594, "ELLAONE": 2.977724608827629, "EVRA": 2.0428543868199105, "GARDASIL": 0.710903305579168, "HYDROCORTISONE": 0.2087225294457939, "KAFTRIO": 0.4936724234732838, "LEVETIRACETAM": 0.1141799880929291, "MEPOLIZUMAB": 0.1586844968151018, "MODERNA": 3.855262478818579, "NUCALA": 0.1441747431840975, "OCRELIZUMAB": 0.6007781029676922, "OLANZAPINE": 0.049962038559942, "PEGASYS": 0.074685911256007, "PEGINTRON": 0.0929021911544715, "SAXENDA": 0.1751238284002336, "SIMPONI": 0.0771090727828952, "SPIKEVAX": 2.785343021766827, "STELARA": 0.2743965537723811, "SUTENT": 0.0229057696720853, "TOZINAMERAN": 1.505155567510161, "VAXZEVRIA": 0.59175500686413, "XOLAIR": 0.0788094761793567, "null": 0.0580162870405843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7507.json
index 0145f02e36c..4a26a3bedba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7507.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7507.json
@@ -1 +1 @@
-{"null": 1.379468903345912}
\ No newline at end of file
+{"COMIRNATY": 6.922893268598663}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7508.json
index 4b779cfe265..e2107ebcc4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7508.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7508.json
@@ -1 +1 @@
-{"COVID19": 2.3499647379914945, "TOZINAMERAN": 1.6633819579489997}
\ No newline at end of file
+{"AIMOVIG": 0.4644988451520755, "BRINTELLIX": 0.2047043383913981, "CHAMPIX": 0.1546926893047577, "COMIRNATY": 8.560149836278343, "ELLAONE": 84.35303207001584, "EVRA": 1.2842858586025658, "GARDASIL": 0.2121431774175021, "HYDROCORTISONE": 0.5859987251071985, "MODERNA": 4.02462284743569, "OCRELIZUMAB": 2.4347790216555563, "PEGASYS": 0.0362429275087443, "SPIKEVAX": 2.149235441258273, "STELARA": 0.6597321425728728, "TOZINAMERAN": 4.028941265441714, "VAXZEVRIA": 1.772648553969127, "null": 0.052818130335734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7509.json
index e65802adaf4..9011d5c6bb3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7509.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7509.json
@@ -1 +1 @@
-{"VAXZEVRIA": 16.215536244593206}
\ No newline at end of file
+{"AIMOVIG": 0.6195506978768816, "ALEMTUZUMAB": 0.2524535066556216, "AUBAGIO": 0.1243206272897157, "BRINTELLIX": 0.2725371085478955, "CHAMPIX": 0.0743364916806732, "COMIRNATY": 10.9651911647472, "ELLAONE": 2.1522009742812838, "EVRA": 1.149287614308465, "GARDASIL": 1.4627043614113897, "HYDROCORTISONE": 0.2912376522282413, "KEPPRA": 0.0501873708880194, "LEMTRADA": 0.324322484403335, "MAVENCLAD": 1.089888690692563, "MODERNA": 4.90167861289466, "OCRELIZUMAB": 1.607327261237086, "OLANZAPINE": 0.0697131167168847, "PEGASYS": 0.0738002604526539, "SAXENDA": 0.2443584222840988, "SPIKEVAX": 2.684526504083049, "STELARA": 0.4278123075084972, "TOZINAMERAN": 3.5346631839098954, "VAXZEVRIA": 0.7636629239090491, "XOLAIR": 0.1401781839747616, "ZYPREXA": 0.1341332098226886, "null": 0.0835484209826421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/751.json
index e0b872f0494..adea616a844 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/751.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/751.json
@@ -1 +1 @@
-{"BONVIVA": 1262.5054649581284, "EVENITY": 224.31030932772043}
\ No newline at end of file
+{"null": 1.6086976435080844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7510.json
index a76a7eec579..dc967709f6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7510.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7510.json
@@ -1 +1 @@
-{"null": 2.5907254632306738}
\ No newline at end of file
+{"COMIRNATY": 2.6914110945341463, "SPIKEVAX": 1.0687785511711578, "null": 0.9892975187697284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7511.json
index 972097c1e97..4fc7cd8d4f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7511.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7511.json
@@ -1 +1 @@
-{"AVANDAMET": 133.53069705627797, "AVANDIA": 101.08552263729445, "LANTUS": 6.3251579321365}
\ No newline at end of file
+{"null": 3.214590044346858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7512.json
index 1ca3c71fca1..7ab609cffc3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7512.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7512.json
@@ -1 +1 @@
-{"KEYTRUDA": 63.60152730447131, "OPDIVO": 185.3268309983824}
\ No newline at end of file
+{"ABACAVIR": 0.5801368308894675, "ABILIFY": 4.88355343032586, "AIMOVIG": 1.4145076185815215, "ANORO": 1.1849833024307392, "APIDRA": 0.4795770560602883, "ARIPIPRAZOLE": 2.7761796528452325, "ATRIPLA": 0.1292457161201198, "AUBAGIO": 0.7697701537605947, "BEDAQUILINE": 1.2132827495258385, "BENLYSTA": 0.8994919183748633, "BEVACIZUMAB": 1.4033563929361292, "BIKTARVY": 4.062789468605201, "BREXPIPRAZOLE": 33.24999593428197, "BRINTELLIX": 1.2016843608953989, "BRIVIACT": 3.498861890931292, "BUDESONIDE": 0.3487908902421608, "BUPRENORPHINE": 3.5958307231319715, "BUSULFAN": 0.5307458635077671, "BYETTA": 0.4182262371464249, "CELLCEPT": 0.3024957648218899, "CHAMPIX": 7.2335849714411795, "CICLOSPORIN": 0.3492138557691668, "CIMZIA": 0.337072690345702, "CLOPIDOGREL": 0.2925502021617194, "COMIRNATY": 0.254513320757493, "COMTAN": 1.4992517140193085, "COSENTYX": 1.0963456030192995, "CYMBALTA": 2.2416703338062374, "DARUNAVIR": 2.067629590194567, "DELAMANID": 2.98590434709295, "DEXAMETHASONE": 0.4982143385176919, "DOCETAXEL": 0.7239038874445368, "DULOXETINE": 3.949970722580476, "EFAVIRENZ": 3.260110530908055, "ELIQUIS": 0.4324621464951009, "ENBREL": 0.1699568317274942, "ENTRESTO": 0.5415122861356985, "ENTYVIO": 1.1183762566928608, "EPCLUSA": 1.8210046280909264, "ERLEADA": 1.3304787590422638, "EXFORGE": 0.4244728428753002, "EXJADE": 0.431175756107011, "FAMPYRA": 3.164981691807969, "FASENRA": 0.8658061904395167, "FASLODEX": 0.5444357514523437, "FENTANYL": 1.5592914121520751, "FIRDAPSE": 1.285527863123199, "FORSTEO": 0.5765679689829355, "FYCOMPA": 1.6730102440816408, "GARDASIL": 1.4179436040164626, "GENVOYA": 2.5728594074446365, "HUMALOG": 1.2285559853840826, "HUMAN": 0.8818074052020702, "HUMIRA": 0.7054021869265112, "IBRANCE": 0.9856806117999408, "IBUPROFEN": 0.5740100700257612, "INCIVO": 2.429141203861877, "INSULIN": 0.9176013203031528, "INTRONA": 2.7581073436713144, "ISENTRESS": 1.398733470857232, "IVABRADINE": 9.96525652703948, "JAKAVI": 0.555190623478836, "JANUMET": 0.998686681725021, "JANUVIA": 0.2824981710278307, "JARDIANCE": 0.4029680424548942, "KAFTRIO": 7.670330024023933, "KALETRA": 0.8815470682283163, "KALYDECO": 4.193822873079055, "KEPPRA": 3.3553174393526044, "KEYTRUDA": 0.1933289334792398, "LACOSAMIDE": 1.448301694202969, "LANTUS": 0.5313467800285805, "LATUDA": 6.165308565013028, "LEVEMIR": 0.4875858078370792, "LEVETIRACETAM": 2.439086821822709, "LEVOFLOXACIN": 1.975231632080767, "LOXAPINE": 9.37636320254358, "LYRICA": 1.5142133499075685, "MERCAPTOPURINE": 3.3230953109504884, "METHOTREXATE": 0.246047620397319, "NORVIR": 1.93718026878199, "NOT": 1.1949689661209553, "OLANZAPINE": 2.3009684849298, "OMALIZUMAB": 0.5662607224059373, "OPSUMIT": 0.4130957170651104, "OPTIMARK": 1.0381518508277732, "PANTOPRAZOLE": 7.761248695735473, "PEGASYS": 2.5043278693789026, "PEGINTERFERON": 3.125436440683549, "PEGINTRON": 3.084396250006178, "PLAVIX": 0.3846115668256511, "PLEGRIDY": 1.907176084954524, "PREGABALIN": 1.12168542891701, "RIBAVIRIN": 0.7497703299141921, "RINVOQ": 0.5383498726529723, "RISPERIDONE": 2.4171961297892444, "SAXENDA": 0.968666143066454, "SERTRALINE": 14.850121211582309, "SHINGRIX": 0.1892304882145058, "SIFROL": 4.908716868074454, "SIMPONI": 0.6745652720092989, "SOVALDI": 1.2086107660680692, "SPIKEVAX": 0.1366766458420796, "SPRYCEL": 0.5333859643574639, "STALEVO": 1.5021397953144502, "STELARA": 0.4358466845980852, "STRIBILD": 0.4118441656087322, "SUBOXONE": 4.072150954830946, "SUTENT": 0.2905236621278267, "TAMIFLU": 4.953582762655146, "TASIGNA": 0.3502177402470491, "TIVICAY": 5.391991499208519, "TOVIAZ": 1.3766409473158308, "TOZINAMERAN": 0.4268940964895131, "TRACLEER": 0.3104549420931969, "TRIUMEQ": 5.24950614546218, "TRULICITY": 1.1339127431692022, "TRUVADA": 0.1994624875437855, "TWINRIX": 0.9337358377613296, "VAXZEVRIA": 0.1257190058913339, "VFEND": 8.103742127294886, "VIAGRA": 1.2626019298912046, "VIMPAT": 2.702442678953964, "VORICONAZOLE": 8.13225930813876, "XELJANZ": 0.9155451059426324, "XOLAIR": 0.6372047054178344, "XTANDI": 0.6815276290207793, "XYREM": 1.2189310550008556, "ZOSTAVAX": 0.4236273251121226, "ZYPREXA": 3.655220285092621, "null": 1.8720024575467071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7513.json
index 8936421ea60..fbf49f8aae7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7513.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7513.json
@@ -1 +1 @@
-{"null": 2.8503638494542263}
\ No newline at end of file
+{"null": 1.102950366923506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7514.json
index 0d6b919ecff..27bdddc03f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7514.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7514.json
@@ -1 +1 @@
-{"KEPPRA": 47.500849804810976, "null": 1.55428195444565}
\ No newline at end of file
+{"BRINTELLIX": 3.3071847642044814, "BYDUREON": 2.187008434185401, "COMIRNATY": 1.826194343117936, "GARDASIL": 0.8162036163979428, "OCRELIZUMAB": 7.616292890702161, "PEGASYS": 0.5440581424303292, "SPIKEVAX": 1.181161079659507, "STELARA": 1.8150801605881328, "TOZINAMERAN": 5.22347467043066, "VAXZEVRIA": 3.9641164585000976, "null": 0.2562333095439276}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7515.json
index 377c064f367..9a50353cac5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7515.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7515.json
@@ -1 +1 @@
-{"ELIQUIS": 7.744050743390675, "SUTENT": 4.721703389372228}
\ No newline at end of file
+{"ABILIFY": 3.037660062574904, "ACTOS": 3.007437960436293, "AFINITOR": 0.4014207496683681, "AIMOVIG": 1.839909089347919, "ANORO": 1.7767996832184196, "APIDRA": 0.7190650276154597, "ARIPIPRAZOLE": 4.026460685842072, "ASENAPINE": 26.26973011913314, "ATRIPLA": 0.0459913240191963, "AUBAGIO": 2.1406167489554577, "AVANDIA": 0.337496442734117, "BENLYSTA": 2.480285546723076, "BENZODIAZEPINES": 18.375343974002057, "BUPRENORPHINE": 1.4590245134692974, "CARIPRAZINE": 22.61356722903168, "CHAMPIX": 3.59661557933796, "CICLOSPORIN": 0.2332538594513521, "CIMZIA": 0.146649347955233, "COMIRNATY": 0.3313113994022861, "COSENTYX": 0.3121638027195971, "CYMBALTA": 1.653761492845633, "DULOXETINE": 4.188983650947622, "ELIQUIS": 0.3825732670949733, "ENTRESTO": 0.4473341530059256, "ENTYVIO": 0.5089483549752772, "FAMPYRA": 1.2428203422309918, "FENTANYL": 3.6492361645694777, "GARDASIL": 1.1742439541114136, "HUMALOG": 1.4413534898983436, "IBRANCE": 2.191088853785059, "IBUPROFEN": 0.6145406120813562, "INLYTA": 1.500131550892271, "JARDIANCE": 0.2124583122523816, "KEPPRA": 2.767185257969913, "KEYTRUDA": 0.2273808952787277, "LANTUS": 1.0740792177219822, "LATUDA": 5.767121979839229, "LEVETIRACETAM": 1.6463232818764333, "LEVOFLOXACIN": 0.3686077975323403, "LYRICA": 2.8883225318105312, "MELATONIN": 1.9437463038754648, "OCRELIZUMAB": 1.5173087571612018, "OLANZAPINE": 4.100635304634359, "OPTIMARK": 24.285711687637445, "OZEMPIC": 12.682707973481596, "PANTOPRAZOLE": 2.608377089218842, "PEGASYS": 1.4921369285334838, "PEGINTRON": 1.2010953968307692, "PLAVIX": 0.5769224685054676, "PREGABALIN": 1.0001492659176994, "RISPERIDONE": 2.661810997863701, "SHINGRIX": 0.6396711721865385, "SIFROL": 3.1143873074312083, "SPIKEVAX": 0.3482143932607387, "STELARA": 0.389907241728449, "SUBOXONE": 2.211060442677512, "SUTENT": 0.3519231121134842, "TAMIFLU": 1.1439632891417442, "TOVIAZ": 3.975150120917871, "TOZINAMERAN": 1.3579117144244095, "TRELEGY": 1.413849698060101, "VAXZEVRIA": 0.2852124857103901, "VFEND": 0.5984113731323563, "VIAGRA": 1.9691825599523305, "VIMPAT": 1.8914976684838796, "VOTRIENT": 0.93246237602397, "XELJANZ": 1.4013528613798902, "XTANDI": 1.022422098276909, "ZOSTAVAX": 0.252903884777297, "ZYPADHERA": 1.441306467775155, "ZYPREXA": 2.1677128202902334, "null": 1.8713944647275031}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7516.json
index 8ad933d4e31..462e3be549c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7516.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7516.json
@@ -1 +1 @@
-{"null": 2.4116525451543898}
\ No newline at end of file
+{"ABILIFY": 0.6998817203537219, "ADCIRCA": 2.539406521659177, "AFINITOR": 0.7407446607453911, "ALIMTA": 1.029958565380712, "ANTIBIOTICS": 16.5333227963875, "ARANESP": 0.4996289281068386, "ARAVA": 0.0692945774282759, "ARIPIPRAZOLE": 1.5044407789969725, "ASPARAGINASE": 2.221652374359274, "AUBAGIO": 0.4022887827767638, "AVANDIA": 0.3059280136793486, "BENZODIAZEPINES": 28.02188055093436, "BEVACIZUMAB": 3.031309131044261, "BIKTARVY": 4.74743931081544, "BUPIVACAINE": 6.938601564994037, "BUPRENORPHINE": 0.9267197153267708, "BUSULFAN": 1.0224174008691491, "BYETTA": 1.2321774324018608, "CELLCEPT": 0.6914118359450375, "CHAMPIX": 1.2408958036068714, "CICLOSPORIN": 1.9483016764191887, "CIMZIA": 0.2363580559997686, "CLOPIDOGREL": 0.4074081683626582, "COMBIVIR": 1.2336242913422146, "COMIRNATY": 0.0259626831730163, "CUBICIN": 3.617554071226496, "CYMBALTA": 1.4904295861923194, "CYTARABINE": 1.8383813324525515, "DEXAMETHASONE": 1.5632431183805393, "DOLUTEGRAVIR": 5.956877568247251, "DULOXETINE": 3.466343919589021, "ELIQUIS": 0.3654762341239899, "EMPAGLIFLOZIN": 2.4093129759983527, "ENOXAPARIN": 1.8730231743844687, "ESOMEPRAZOLE": 1.9808127314796145, "EXJADE": 3.559153564554105, "FASLODEX": 0.5574845767900641, "FENTANYL": 3.384303810099772, "FYCOMPA": 2.8803371331903262, "GARDASIL": 0.7797116798852103, "GLUCAGON": 16.45119628948413, "HARVONI": 1.3317767306177888, "HUMALOG": 0.3934883544266019, "IBRANCE": 0.2739646598124509, "IBUPROFEN": 2.594181172410285, "JANUMET": 1.077580578143608, "JANUVIA": 1.4163298029722375, "JARDIANCE": 0.6217876572296787, "KALETRA": 0.8744699304966693, "KEPPRA": 2.2384745188381934, "KEYTRUDA": 0.584182039118812, "KYMRIAH": 5.526766816122155, "LACOSAMIDE": 2.0492778987998506, "LANTUS": 0.3954518060638415, "LATUDA": 1.059515655733, "LEVETIRACETAM": 4.058162025087208, "LEVOFLOXACIN": 1.5658952683109006, "LYRICA": 1.3243309459177646, "MEKINIST": 1.3883026841269313, "MEMANTINE": 7.662391456502933, "METHOTREXATE": 0.5768323740140163, "MIDAZOLAM": 2.4650465913666406, "NALOXONE": 25.83439398790766, "NEULASTA": 1.656641420719187, "NEXAVAR": 0.5729009173043671, "NOT": 1.838959649676918, "NPLATE": 1.3992529155946336, "OLANZAPINE": 5.562990810457161, "ONCASPAR": 4.106175822646401, "OPSUMIT": 1.8669193933800787, "OPTIMARK": 30.643123341667888, "OXYBUTYNIN": 5.412152830409378, "PALIPERIDONE": 14.321456635387635, "PANTOPRAZOLE": 1.26716248120033, "PEGASYS": 1.3529019433641822, "PEGINTERFERON": 0.9224764602370066, "PEGINTRON": 3.210409064732784, "PLAVIX": 1.2113955631174689, "POSACONAZOLE": 6.86516154137159, "PRIALT": 19.506438340585365, "REVLIMID": 2.4585997727399915, "RIBAVIRIN": 2.2090090052939235, "RISPERIDONE": 4.162468380293945, "RIVASTIGMINE": 45.407689271142, "SOLIRIS": 1.7035289594255545, "SPIKEVAX": 0.4706581250049453, "STIVARGA": 0.56543193686693, "SUBOXONE": 1.469624133343595, "SUTENT": 0.5335223295756146, "TACROLIMUS": 4.740266931794532, "TAMIFLU": 1.313877068708196, "TIGECYCLINE": 13.007818977370368, "TOZINAMERAN": 0.117475753702495, "TRACLEER": 1.6010518048295723, "VELTASSA": 2.292959871453379, "VFEND": 0.8517735880316252, "VORICONAZOLE": 1.896381440431602, "VOTRIENT": 1.0057929085043085, "XTANDI": 1.1744686407106522, "YESCARTA": 8.193608969219776, "ZOSTAVAX": 0.8069034401677776, "ZYPREXA": 2.4106202658282565, "null": 1.8027805918675697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7517.json
index 5b73b25cf0a..6fab8872ae9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7517.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7517.json
@@ -1 +1 @@
-{"BRILIQUE": 63.491637732988245, "null": 3.3210446427369886}
\ No newline at end of file
+{"FENTANYL": 183.16111227504535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7518.json
index d0d9bc637f7..971d767566a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7518.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7518.json
@@ -1 +1 @@
-{"null": 1.0692175350699895}
\ No newline at end of file
+{"COMIRNATY": 0.8228964553274088, "VAXZEVRIA": 0.7891402518750698, "null": 0.6391236183990162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7519.json
index 4fa07f561e9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7519.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7519.json
@@ -1 +1 @@
-{"BUDESONIDE": 9.28894856334398, "COSENTYX": 11.382685651781973, "COVID19": 1.544965192506908, "NUCALA": 34.29703659789128, "TOZINAMERAN": 1.3045642547141625}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/752.json
index ffc87f33759..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/752.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/752.json
@@ -1 +1 @@
-{"CARFILZOMIB": 125.2988117791388, "KYPROLIS": 172.1886774658512, "SOLIRIS": 216.3983531703212}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7520.json
index 0e5d7f80070..a673fb7a279 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7520.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7520.json
@@ -1 +1 @@
-{"BRIDION": 12.18447378508978, "BRILIQUE": 35.88903264663028, "FENTANYL": 3.214163361885351, "IRBESARTAN": 9.985936513252224, "IVABRADINE": 169.8045097608625, "LEVETIRACETAM": 3.0138993808810834, "TICAGRELOR": 44.90060240060416, "VFEND": 3.929971468899817, "VIMPAT": 11.929946652569347, "null": 3.665851354021635}
\ No newline at end of file
+{"null": 3.823688295155416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7521.json
index e2ce068fb60..52e90714c4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7521.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7521.json
@@ -1 +1 @@
-{"GARDASIL": 4.011747036133462, "TOZINAMERAN": 1.0620432030725049, "null": 1.5972148906987491}
\ No newline at end of file
+{"null": 0.4920994718959467}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7522.json
index d4c482c87e6..804a36154e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7522.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7522.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 2.257763818856616, "ARIPIPRAZOLE": 2.422914860907392, "ATAZANAVIR": 2.189593043333463, "AVANDIA": 1.0572043755742568, "BEDAQUILINE": 2.07513595212826, "BRILIQUE": 7.43863377015445, "CANCIDAS": 3.865508742399375, "EBIXA": 14.31911589364448, "ENTRESTO": 3.0761555731222883, "FENTANYL": 2.5411742579222394, "IBUPROFEN": 2.4331116040741114, "IRBESARTAN": 9.246055247944906, "IVABRADINE": 61.21954376347272, "KALETRA": 6.114027334292162, "LACOSAMIDE": 4.872571057607204, "LEMTRADA": 6.045703948241426, "LOPINAVIR": 9.80438030452272, "MICARDIS": 1.6131952176035662, "MIDAZOLAM": 1.6740841388652217, "MULTAQ": 4.171222645077596, "OLANZAPINE": 2.123597058103172, "OLYSIO": 7.737885858959147, "PREGABALIN": 6.626391811205769, "PRIALT": 44.4033289509607, "PROPRANOLOL": 7.984507151868709, "RAPISCAN": 29.78775491236836, "REBETOL": 4.087386703594066, "REMDESIVIR": 26.579423334869126, "RIBAVIRIN": 1.5952686330560155, "SIMEPREVIR": 25.700989384498843, "SPIRONOLACTONE": 9.203078730037015, "THALIDOMIDE": 4.420869636439437, "VALSARTAN": 4.600619571789881, "VEKLURY": 85.14390711368713, "VIMPAT": 5.197284563639514, "XALKORI": 7.728385090754297, "XARELTO": 2.7091539301764347, "ZYPREXA": 1.520743226008799, "null": 3.612877904159472}
\ No newline at end of file
+{"null": 0.3425776569616238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7523.json
index 4d1892e0384..2dfcd10865d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7523.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7523.json
@@ -1 +1 @@
-{"AVAMYS": 9.961862135316215, "CHAMPIX": 1.7614717970949514, "CICLOSPORIN": 1.3257626621610965, "CIMZIA": 1.694839621766425, "COSENTYX": 5.102520606158166, "ENTYVIO": 2.7544747357014248, "ESBRIET": 3.036420690062744, "GLYCOPYRRONIUM": 68.02362408683393, "HIZENTRA": 3.3844417600672063, "HUMIRA": 2.035908287864176, "IBRANCE": 1.96454427075478, "JANUVIA": 4.322411377141879, "MEPOLIZUMAB": 16.476295228475948, "METHOTREXATE": 2.541106465165386, "NUCALA": 4.600022501682807, "OMALIZUMAB": 6.591708898377648, "OPSUMIT": 6.576406023088784, "PEGINTRON": 1.577663132981244, "TOZINAMERAN": 2.2032655566132475, "TRELEGY": 2.5131455547262185, "VIAGRA": 2.6223459312784687, "XELJANZ": 3.0791369909766315, "XOLAIR": 7.812264648315513, "ZOSTAVAX": 2.2967643221686287}
\ No newline at end of file
+{"null": 0.6073702440832566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7524.json
index ee325a47d71..9e2b0eceb1f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7524.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7524.json
@@ -1 +1 @@
-{"ACLIDINIUM": 20.17617332845585, "ANORO": 6.188026535275771, "AUBAGIO": 1.7360057879894537, "BENLYSTA": 2.621254615195766, "BUDESONIDE": 28.029947910834515, "BYETTA": 1.4881959385000632, "CIMZIA": 2.307452977914312, "COSENTYX": 1.0097207405935538, "ENBREL": 1.2638386454467687, "ENTYVIO": 1.8978934674449568, "ESBRIET": 2.092473032193897, "FASENRA": 3.828070718963246, "HIZENTRA": 5.2703287194656205, "HUMIRA": 2.2613387640202336, "IBRANCE": 2.835737815491773, "IRON": 13.942227610206992, "LANTUS": 1.0154429038465749, "LYRICA": 2.117530144028384, "MEPOLIZUMAB": 5.434459252441535, "METHOTREXATE": 1.0856348927791564, "NUCALA": 2.560227120934633, "OMALIZUMAB": 5.591133500570365, "OPSUMIT": 2.505655099495208, "ORKAMBI": 7.228140265439216, "PEGASYS": 1.5790844607894188, "PLAVIX": 1.6167626459753257, "STELARA": 1.304657009958485, "SUTENT": 1.7611253933056967, "TOVIAZ": 2.8776509727295245, "TOZINAMERAN": 1.3254358351838516, "TRELEGY": 3.6608284192976015, "VIAGRA": 1.80685381638456, "XELJANZ": 5.123468849937683, "XOLAIR": 4.006661407798301, "XTANDI": 2.6194753839403355, "ZOSTAVAX": 3.938583846328531, "null": 1.1354173727915915}
\ No newline at end of file
+{"COMIRNATY": 0.5651159166289162, "VAXZEVRIA": 0.996822548482486, "null": 0.3029945237305251}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7525.json
index d1ae0a0298b..69f96c00b82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7525.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7525.json
@@ -1 +1 @@
-{"AVAMYS": 2.794226439797592, "COVID19": 15.0152226575333, "TOZINAMERAN": 5.47308492743202, "XOLAIR": 1.4612895702827515}
\ No newline at end of file
+{"MEKINIST": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7526.json
index c5ea797fc83..3286602e310 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7526.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7526.json
@@ -1 +1 @@
-{"AVANDAMET": 23.844714122606327, "AVANDIA": 22.91092917009161, "BUDESONIDE": 1.2303561902479332, "BYETTA": 3.329253637347524, "ELIQUIS": 2.04756402481731, "ENTRESTO": 1.9143357662452496, "EXFORGE": 4.278199541453614, "FENTANYL": 3.796692923995449, "IRBESARTAN": 7.119084460301326, "MICARDIS": 7.239345476126208, "PLAVIX": 1.4356638181286716, "VIMPAT": 31.477807612871057, "null": 2.2474099696486927}
\ No newline at end of file
+{"null": 2.525096794861536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7527.json
index 63973e7fdfd..02682addf62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7527.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7527.json
@@ -1 +1 @@
-{"HIZENTRA": 58.83111044456636, "NUCALA": 8.964327499965702, "ORKAMBI": 148.9677654427281, "XOLAIR": 7.436710230346999, "null": 1.097230711068644}
\ No newline at end of file
+{"null": 1.1143824523374972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7528.json
index 83fa2ae45cd..4960314d82e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7528.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7528.json
@@ -1 +1 @@
-{"ACLIDINIUM": 15.256119622958796, "COMIRNATY": 1.2888456302138038, "COVID19": 7.26351454259773, "ENBREL": 1.330141096473497, "OMALIZUMAB": 2.1685926245694995, "SPIKEVAX": 1.5691872639886577, "TOZINAMERAN": 3.991756899755904, "VAXZEVRIA": 1.1967924137087398, "XOLAIR": 1.1856119010369237, "ZOSTAVAX": 1.9422748216827024}
\ No newline at end of file
+{"COMIRNATY": 0.8424105203734893, "GARDASIL": 12.166718115190466, "null": 0.4423718904223737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7529.json
index b2eb6cc761f..d56838552ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7529.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7529.json
@@ -1 +1 @@
-{"BUDESONIDE": 87.35260589729205}
\ No newline at end of file
+{"null": 0.6781670157280706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/753.json
index c80df53847a..b9626cfc060 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/753.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/753.json
@@ -1 +1 @@
-{"ABACAVIR": 6.40049620029478, "AMIKACIN": 45.750479287930375, "ATAZANAVIR": 32.049539420148186, "CELLCEPT": 7.596887484437276, "CICLOSPORIN": 7.700720085272615, "DESCOVY": 59.78808350513631, "ISENTRESS": 22.62733494897861, "JAKAVI": 13.563233624924422, "METHOTREXATE": 5.047644442187632, "SIMPONI": 9.346436989640852, "STELARA": 3.319029795260676}
\ No newline at end of file
+{"JIVI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7530.json
index 7a2b0baa187..a46de1c484c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7530.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7530.json
@@ -1 +1 @@
-{"APIXABAN": 9.28820854646507, "ARIPIPRAZOLE": 101.9993437467453, "OLANZAPINE": 5.454552729669046}
\ No newline at end of file
+{"COMIRNATY": 0.5107310436390027, "null": 0.3044736088603003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7531.json
index 0a536ea58d3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7531.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7531.json
@@ -1 +1 @@
-{"ABILIFY": 1.892010657597812, "ACLASTA": 11.970369250518496, "AMINOSALICYLIC": 1.8336512299377743, "ARIPIPRAZOLE": 6.621682081730261, "BEDAQUILINE": 1.848770499039965, "BRIDION": 3.4081481656065704, "CYTARABINE": 4.523188940875042, "DARZALEX": 1.6813823396897496, "DELAMANID": 6.6353804990705205, "DEXMEDETOMIDINE": 10.079415217941746, "DOCETAXEL": 1.3430542953253195, "DULOXETINE": 2.338144417202312, "ENOXAPARIN": 3.452923163483174, "FENTANYL": 1.8934829500321595, "FIRDAPSE": 2.104927642603102, "HYDROCORTISONE": 1.6223059509558853, "IBUPROFEN": 2.717644410841382, "JARDIANCE": 1.149673539835507, "KYMRIAH": 1.5566780572450922, "LACOSAMIDE": 3.424921018239825, "LEMTRADA": 1.9014100680280623, "LEVOFLOXACIN": 1.29650099058281, "MELATONIN": 3.3746216081862626, "MIDAZOLAM": 6.824046963811249, "NALOXONE": 37.17687997493727, "OLANZAPINE": 5.192586654556625, "PALIPERIDONE": 17.46551794281048, "PRIVIGEN": 1.2341890191393268, "RISPERIDONE": 3.683198345001944, "SPINRAZA": 2.5668289144229326, "TRULICITY": 1.3149495337341877, "ZYPADHERA": 4.280952019551647, "ZYPREXA": 3.3499115780926965, "null": 2.274503916784505}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7532.json
index c78873dcbab..ce23a3ac208 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7532.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7532.json
@@ -1 +1 @@
-{"ABATACEPT": 12.640464995476274, "ACLIDINIUM": 2.639619963303937, "ADALIMUMAB": 2.3062913467358004, "ADEMPAS": 1.9324146665437525, "ALEMTUZUMAB": 1.6603942179963895, "ANORO": 2.0928202214131453, "ARAVA": 5.587221436968477, "AUBAGIO": 1.4115966004253695, "AVAMYS": 9.980935133095418, "BELIMUMAB": 3.493238138392944, "BENLYSTA": 5.504484730404638, "BUDESONIDE": 3.0424069475120654, "CHLORHEXIDINE": 40.41583815752922, "CIMZIA": 15.466137674384894, "CINRYZE": 2.282089771147339, "CLOFARABINE": 5.567235863554169, "COMBIVIR": 2.298957535510994, "COSENTYX": 2.546945650341358, "DESCOVY": 2.1372414502498835, "DULOXETINE": 1.0814161077100402, "DUPIXENT": 4.080952029629663, "ENBREL": 1.7456327702429897, "ENTYVIO": 2.9998766469928646, "ERELZI": 7.140434726892647, "ESBRIET": 1.0987827558841228, "FASENRA": 2.948986213664691, "FLUTICASONE": 1.395690923762979, "GALAFOLD": 2.801534104790178, "GARDASIL": 1.2669795248948863, "HIZENTRA": 15.21091654878596, "HUMAN": 1.3629758781122951, "HUMIRA": 2.542782332680828, "HYQVIA": 10.14392377118188, "IBRANCE": 1.6654597686660988, "IMBRUVICA": 1.633481922895113, "INCRUSE": 1.1138580744845896, "KAFTRIO": 1.5342884224013524, "KALYDECO": 6.084885762412976, "KESIMPTA": 1.2972686491342205, "LEFLUNOMIDE": 3.1230218728682204, "MEPOLIZUMAB": 5.035211994635872, "METHOTREXATE": 2.014928352450434, "NUCALA": 5.587272853487301, "OCALIVA": 1.8425093838619937, "OMALIZUMAB": 6.78077165200097, "OPSUMIT": 1.6743803658497354, "ORKAMBI": 4.463458862366823, "OZEMPIC": 5.467803212446788, "PEGASYS": 1.3485232417412327, "POSACONAZOLE": 2.3034153117200864, "PRIVIGEN": 1.9558255867262215, "RELVAR": 3.3306636833816903, "REMICADE": 2.495202229720168, "REVLIMID": 1.045778495445132, "RINVOQ": 1.5418053891575922, "RITUXIMAB": 2.604384826438487, "ROACTEMRA": 1.4528778528837667, "RUCONEST": 6.101029614380689, "RUXOLITINIB": 1.2135348785755045, "SIMPONI": 3.250511931828776, "SOLIRIS": 1.2258156329243954, "SPRYCEL": 1.104374782853501, "STELARA": 1.7687783838398945, "TRELEGY": 1.1086614866007285, "VARENICLINE": 12.125655844010716, "XELJANZ": 5.764374498323321, "XOLAIR": 4.743780779947715, "XYREM": 3.5627476951660317, "ZOSTAVAX": 1.8726586294144147}
\ No newline at end of file
+{"null": 0.6576612364450601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7533.json
index 09e2549ad8e..ded352c9703 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7533.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7533.json
@@ -1 +1 @@
-{"HUMIRA": 18.20069535634932, "XELJANZ": 11.755807438517715}
\ No newline at end of file
+{"null": 0.8400700673806651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7534.json
index cdd8f04a931..6fe003d892b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7534.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7534.json
@@ -1 +1 @@
-{"ASPARAGINASE": 34.31395774472666, "BUDESONIDE": 43.91451549086277, "CYTARABINE": 21.267871927788896, "IRON": 126.46166740720912}
\ No newline at end of file
+{"ADENURIC": 46.54547915172089, "COMIRNATY": 1.1114060568725033, "NEXAVAR": 2.9009174589856137, "NOVOSEVEN": 48.53319812038328, "PEGASYS": 1.967306058230887, "SPIKEVAX": 0.632235746216991, "TESTOSTERONE": 49.82377531698251, "TOZINAMERAN": 0.6752369619192453, "VAXZEVRIA": 2.151796883319987, "null": 0.3677891649937586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7535.json
index a50cea23552..7c474540fe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7535.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7535.json
@@ -1 +1 @@
-{"ATRIPLA": 6.293584189671739, "COMIRNATY": 1.4287756387905233, "SPIKEVAX": 1.4519684642970023, "TOZINAMERAN": 2.602741907079197, "TRUVADA": 3.3138221009016453}
\ No newline at end of file
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7536.json
index ecfa1d59bda..ccc9c24b94f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7536.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7536.json
@@ -1 +1 @@
-{"ARAVA": 4.2873256399977535, "AZATHIOPRINE": 4.836823935372974, "BENLYSTA": 5.598950467182258, "CELLCEPT": 1.7828791271851152, "CIMZIA": 2.0358165845386416, "COSENTYX": 4.619092315069047, "ENBREL": 6.021931312365752, "GARDASIL": 2.0507832578007363, "HUMIRA": 4.729415034644246, "IPILIMUMAB": 11.430293049913464, "KEYTRUDA": 6.088956732040036, "LEFLUNOMIDE": 11.65216857707072, "LYRICA": 2.8975300755347253, "MICARDIS": 5.987998800269721, "OPDIVO": 3.701618463095721, "PEGASYS": 2.075421285968232, "PEGINTRON": 2.178699722143336, "PEMBROLIZUMAB": 8.423800994486738, "SIMPONI": 3.96807228992891, "TELMISARTAN": 26.32475250699679, "TOZINAMERAN": 1.1980824743075271, "XELJANZ": 5.333683861475484, "ZOSTAVAX": 1.6511290053383794}
\ No newline at end of file
+{"null": 0.518568421952164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7537.json
index 7faa2a9caf8..0f075a6701b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7537.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7537.json
@@ -1 +1 @@
-{"null": 2.0464318866351654}
\ No newline at end of file
+{"DEXAMETHASONE": 33.05862516475707, "ELIQUIS": 12.506017112625871, "null": 0.8817170655954313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7538.json
index a3adeae895a..056e5b4282b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7538.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7538.json
@@ -1 +1 @@
-{"ATRIPLA": 114.8498199553552, "KALETRA": 8.029968308061274, "STRIBILD": 24.51679949132032, "TRUVADA": 44.38344892571856, "VIREAD": 17.918695881925714}
\ No newline at end of file
+{"null": 1.0013117514195469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7539.json
index c4b7f3f9226..a73c86dba65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7539.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7539.json
@@ -1 +1 @@
-{"APIXABAN": 1.4085820103542306, "APREMILAST": 4.924091944392407, "BUPRENORPHINE": 2.6337676566742574, "COSENTYX": 1.066442459675981, "CYMBALTA": 2.192138576713639, "CYTARABINE": 3.16818893193674, "DEXAMETHASONE": 3.3740446283076952, "ELIQUIS": 1.7708590299948952, "FENTANYL": 4.842838896628899, "GARDASIL": 1.389782197936583, "IBRANCE": 1.1106340776658432, "IMIQUIMOD": 54.20172693234086, "JARDIANCE": 2.3003379658857126, "KEPPRA": 1.603938231541472, "METHOTREXATE": 2.323556608149254, "NAGLAZYME": 7.639355211964621, "OLANZAPINE": 1.0529046425052802, "OPTIMARK": 6.947744541526506, "PEGINTRON": 1.564470410901586, "SUTENT": 2.739269224730219, "XELJANZ": 1.220710569792464, "ZOSTAVAX": 2.559447183834304, "ZYPREXA": 1.018401773658875, "null": 1.2750194071698684}
\ No newline at end of file
+{"ALIMTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/754.json
index d22ceaa04f5..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/754.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/754.json
@@ -1 +1 @@
-{"AMIKACIN": 534.8625835358554}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7540.json
index 82b25fc6085..df3b847d9d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7540.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7540.json
@@ -1 +1 @@
-{"BUDESONIDE": 1.917300263200619, "CICLOSPORIN": 5.612532335146753, "COSENTYX": 2.4692166962664155, "DULOXETINE": 4.654891398941683, "ELIQUIS": 1.4910737214377048, "ENBREL": 1.2513290746928063, "HYDROCORTISONE": 27.395409780727213, "MEPOLIZUMAB": 6.603647336083183, "METHOTREXATE": 1.8099761593336057, "NEXAVAR": 1.158975632463709, "NUCALA": 1.670695833678106, "OMALIZUMAB": 4.5025123963563685, "OPTIMARK": 22.917234094784803, "PROTOPIC": 93.01369960056503, "RENVELA": 569.6801783734003, "SUTENT": 6.306909146285564, "null": 1.860301867742583}
\ No newline at end of file
+{"ABACAVIR": 0.6096201746340474, "ABILIFY": 0.4270445832825656, "ACTOS": 2.6123337144185106, "AERIUS": 1.844670755008666, "AFINITOR": 0.4228227631982694, "AMIKACIN": 3.01167565933921, "AMINOSALICYLIC": 0.905564775920919, "APROVEL": 3.200443283277981, "ARANESP": 0.3778965690315776, "ARAVA": 0.0549230660077997, "ARIPIPRAZOLE": 0.9175272928485652, "ASPARAGINASE": 0.5646342719711892, "ATAZANAVIR": 1.081022498595453, "ATRIPLA": 0.4089232128281357, "AVANDIA": 0.4481316283898354, "AVASTIN": 0.5710548819237713, "BEDAQUILINE": 1.04766009737747, "BIKTARVY": 0.6182030653405052, "BORTEZOMIB": 1.2760127286722391, "BRAFTOVI": 0.7466206275975749, "BUDESONIDE": 0.1841062675437072, "BUPRENORPHINE": 0.3102160645399888, "BUSULFAN": 1.0388398066270212, "BYETTA": 1.1748493576347718, "CANAGLIFLOZIN": 12.938334642287456, "CAPECITABINE": 0.9289778574696848, "CASPOFUNGIN": 1.7351755076356328, "CELECOXIB": 2.4527901017766607, "CELLCEPT": 0.9412882654598848, "CHAMPIX": 0.1859775838382347, "CICLOSPORIN": 0.8495825972726218, "CLOPIDOGREL": 0.7024974272725597, "COAPROVEL": 3.710376765448314, "COMBIVIR": 0.752869694451389, "COMIRNATY": 0.0227012373531807, "CYMBALTA": 0.2218595606518437, "CYTARABINE": 0.4801844959916432, "DAPAGLIFLOZIN": 15.461530444811292, "DARUNAVIR": 2.4600331993125453, "DELAMANID": 2.2356882101608258, "DEXAMETHASONE": 2.112223842098328, "DOXORUBICIN": 0.8336714333467837, "DULOXETINE": 1.2387629897023762, "EFAVIRENZ": 1.6903508427466336, "ELIQUIS": 0.0744681301271929, "EMPAGLIFLOZIN": 21.154526142699968, "EMTRICITABINE": 5.552220482419975, "ENTRESTO": 1.0107401553390691, "EPIVIR": 2.752790521771012, "ESOMEPRAZOLE": 47.041116391867455, "EUCREAS": 12.854079728363898, "EVEROLIMUS": 1.9969067137878551, "EXFORGE": 1.335081127794119, "EXJADE": 4.195162887286397, "EXVIERA": 2.8869399621863963, "FENTANYL": 2.8821038100281946, "FORXIGA": 8.420570279138053, "GANCICLOVIR": 4.5232319866114725, "GLIBENCLAMIDE": 5.124426232136686, "GLUCAGON": 5.638466002694288, "HEPSERA": 9.569751333342657, "HUMALOG": 0.3067334769657246, "HYDROCORTISONE": 1.4504992683947784, "IBUPROFEN": 8.897707699755824, "INSULIN": 1.0126460765253358, "INVOKANA": 35.09673005468178, "IRBESARTAN": 3.1010784619048923, "IRINOTECAN": 1.4270097316119097, "ISENTRESS": 3.1270053033679903, "JANUMET": 4.440905345993113, "JANUVIA": 1.3917883791284753, "JARDIANCE": 9.692893677509126, "KALETRA": 1.9132331844443529, "KEPPRA": 1.236468341083581, "KEYTRUDA": 0.4515778203958609, "KYMRIAH": 1.6713859106720148, "LACOSAMIDE": 3.252722006761424, "LAMIVUDINE": 5.42732983525791, "LANTUS": 0.119021311234769, "LEVETIRACETAM": 2.5634366948375056, "LEVOFLOXACIN": 1.0826157961559555, "LOPINAVIR": 4.7148065446160246, "LYRICA": 0.719386291202567, "MANNITOL": 7.857124829315548, "METFORMIN": 4.27529891119734, "MICARDIS": 0.7191359446355469, "MIDAZOLAM": 6.130771882591364, "MISOPROSTOL": 12.174774813714428, "NEXAVAR": 0.5459457079165938, "NORVIR": 2.035549662981824, "NOVORAPID": 0.3920582545296855, "OLANZAPINE": 1.631145433706435, "PANTOPRAZOLE": 1.112646468358585, "PEGASYS": 0.2170719602405875, "PEGINTRON": 0.2586293809785854, "PLAVIX": 0.3043558645295284, "PREGABALIN": 1.5801504027697928, "PROPRANOLOL": 2.135343835668253, "RASILEZ": 1.8866234096652847, "REPAGLINIDE": 11.586812331360129, "RISPERIDONE": 2.7703926846867457, "ROTATEQ": 2.374378329602276, "SILDENAFIL": 1.3646068188136664, "SOLIRIS": 0.3656593697006066, "SPIKEVAX": 0.0311950380553519, "SPINRAZA": 1.454391888426489, "SPIRONOLACTONE": 8.099474746460112, "SUTENT": 0.1331310950477135, "TENOFOVIR": 15.265377300721712, "TOZINAMERAN": 0.022791032274706, "TRACLEER": 1.223797553109092, "TRULICITY": 0.7994481163403317, "TRUVADA": 0.6494510717974404, "VALSARTAN": 2.0510917774333177, "VAXZEVRIA": 0.0154895187190065, "VELMETIA": 14.374027664108525, "VELTASSA": 4.637132775526004, "VFEND": 0.6751250939719219, "VICTOZA": 0.8620041084362164, "VILDAGLIPTIN": 8.964177702938553, "VIREAD": 3.2378047216976333, "XELJANZ": 0.2982211974332394, "ZYPREXA": 0.9327246342284122, "null": 2.8606941718904038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7541.json
index 50bc132b18f..afe8f7e61fd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7541.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7541.json
@@ -1 +1 @@
-{"ALDARA": 9.393943348875805, "BENLYSTA": 1.081855274561126, "BRINTELLIX": 1.4255948917283057, "COMIRNATY": 1.3891293059764085, "CONTRAST": 10.057376272929451, "COSENTYX": 1.7732196751029845, "COVID19": 1.379432832876031, "ESBRIET": 1.3623810731786368, "HYDROCORTISONE": 18.185668122103763, "LYRICA": 1.310532259023777, "MIRVASO": 105.16860408228771, "OPTIMARK": 4.085533061709405, "PROTOPIC": 26.887187989209444, "QUTENZA": 6.237275929931049, "RINVOQ": 1.4197380904375123, "SHINGRIX": 1.7479978536967418, "SPIKEVAX": 1.2057328133148355, "TOZINAMERAN": 1.441045931768706, "VAXZEVRIA": 1.1369420647485209, "XOLAIR": 1.3932854872217104, "ZYCLARA": 9.35178344231789, "null": 1.361865083273441}
\ No newline at end of file
+{"CELECOXIB": 24.363058398203624, "FORXIGA": 5.722896762965076, "null": 5.488023281268098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7542.json
index a4e8b4ff1f9..ac768b9e727 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7542.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7542.json
@@ -1 +1 @@
-{"AIMOVIG": 2.3605921477931244, "AUBAGIO": 1.0970826674612804, "BENLYSTA": 1.656518440237497, "BYETTA": 1.1276191658785502, "CELLCEPT": 8.499873104532156, "CICLOSPORIN": 3.401106055511613, "CIMZIA": 2.6504238543620406, "COSENTYX": 1.3391116060612307, "ELIQUIS": 2.2377037970151403, "ENTYVIO": 1.7504003263948622, "ESBRIET": 2.956989328932642, "EXFORGE": 2.187589551048494, "HUMALOG": 1.0314638239283085, "HUMIRA": 3.101425179814654, "JAKAVI": 13.001622865158804, "JANUMET": 1.430485942836441, "LANTUS": 1.9198220005167572, "MEKINIST": 2.330630129479124, "METHOTREXATE": 1.3253101884607044, "RAPAMUNE": 26.048425817844425, "REVLIMID": 7.364434677399502, "RINVOQ": 3.940254848627724, "ROACTEMRA": 1.521023428510139, "SIMPONI": 4.784476622906233, "SOLIRIS": 1.1640568057305256, "SPRYCEL": 1.7831699937114207, "STELARA": 5.665972084085134, "TREMFYA": 4.76401523562448, "VFEND": 7.806541663947764, "VIAGRA": 3.5691967828631066, "XELJANZ": 12.087827958796744, "XOLAIR": 1.198626761031163, "ZELBORAF": 5.579448324591023, "ZOSTAVAX": 5.461614999824607, "null": 1.9390690464331013}
\ No newline at end of file
+{"ABACAVIR": 1.5905168453656526, "ABILIFY": 83.10786137233795, "ARIPIPRAZOLE": 9.386361982991838, "BIKTARVY": 24.792700553421984, "COMIRNATY": 0.2009881365301111, "CYMBALTA": 0.603238101407192, "GARDASIL": 0.8923147213024054, "INSULIN": 5.6456847864414215, "JANUMET": 2.136933323656296, "KEPPRA": 3.072743108669976, "OLANZAPINE": 6.068591727051416, "PEGASYS": 1.2709871489205211, "PREGABALIN": 4.534439873875772, "SPIKEVAX": 0.0906402071443695, "VAXZEVRIA": 0.0421164852756378, "ZYPREXA": 10.252153690012651, "null": 0.8200265942766466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7543.json
index 1c36a258606..5dbb04a55f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7543.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7543.json
@@ -1 +1 @@
-{"ATEZOLIZUMAB": 425.0378573062477, "COSENTYX": 20.578440603673084, "null": 1.1422987304092451}
\ No newline at end of file
+{"CICLOSPORIN": 1.933134055158375, "COMIRNATY": 0.1322203472020046, "INVOKANA": 54.81103034817952, "JARDIANCE": 1.635099468924298, "KEPPRA": 2.7598997707470683, "LANTUS": 0.8219822179294215, "LEVETIRACETAM": 6.244520019860818, "SPIKEVAX": 0.2312825864212722, "ZOSTAVAX": 1.7189258843924418, "null": 2.197151916632869}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7544.json
index 793ab28b2f1..db771384970 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7544.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7544.json
@@ -1 +1 @@
-{"COSENTYX": 3.16153305920081, "SUTENT": 4.1650298740959295, "VOTRIENT": 6.857300794189839, "null": 1.3762727491110294}
\ No newline at end of file
+{"SPIKEVAX": 38.01847077053611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7545.json
index b72d64ca228..5003122d937 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7545.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7545.json
@@ -1 +1 @@
-{"ADEMPAS": 2.2127222165957288, "AMBRISENTAN": 2.4693956830556747, "APIDRA": 1.3334198847149128, "AUBAGIO": 1.1225101740933134, "BEDAQUILINE": 2.4924144560078094, "BENLYSTA": 2.563342710871376, "BETAFERON": 1.0317460231348452, "BRAFTOVI": 1.7396447658816805, "BRILIQUE": 1.1524166661149895, "CABOMETYX": 1.1638275505787632, "CAELYX": 1.320082934532425, "CLOPIDOGREL": 1.105976257303504, "CONTRAST": 15.453762978229731, "COSENTYX": 1.170073738276991, "COTELLIC": 1.9879094574297669, "DUPIXENT": 4.150812689807531, "ELIQUIS": 1.9248221620376187, "ENOXAPARIN": 1.149027904856274, "ESBRIET": 2.074626399166184, "EVEROLIMUS": 2.0684483389475434, "EXFORGE": 1.1602098123019031, "GALVUS": 1.5722793647424376, "GARDASIL": 1.329029131850467, "HYDROCORTISONE": 1.5330560844045824, "INCIVO": 1.0885112816216156, "INLYTA": 1.2592019837385071, "IRESSA": 1.046293004720087, "IRON": 3.336688381697896, "KISQALI": 1.7065810608754146, "LIXIANA": 2.1109261913051243, "MENVEO": 1.7809116792779116, "METHOTREXATE": 1.2086119756275715, "MMRVAXPRO": 1.4282005402206623, "NEXAVAR": 1.071029748706375, "NINLARO": 1.510764502882353, "OPTIMARK": 19.06909304230157, "PLAVIX": 1.3391422100167127, "PLEGRIDY": 1.1788335547676372, "PREGABALIN": 1.354902452030342, "PROTOPIC": 9.592735169271606, "REVATIO": 1.04839847289206, "RINVOQ": 1.4464916770349583, "ROTATEQ": 1.3049888093868298, "SHINGRIX": 1.5224973488020987, "SIMPONI": 1.6006329584034795, "STALEVO": 1.2752060145682425, "SUTENT": 5.656792768959901, "SYNAGIS": 1.6445531725235945, "TORISEL": 1.6217908191181345, "TOZINAMERAN": 1.1308165699801118, "TRELEGY": 1.0176816054406237, "VAXZEVRIA": 1.244368772867391, "VIAGRA": 2.9061809066167443, "VOTRIENT": 3.3253518754701754, "XOLAIR": 1.1536181871690727, "null": 1.2930607128514906}
\ No newline at end of file
+{"SPIKEVAX": 11.323023439499815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7546.json
index a055c06e28e..0339c5fcb21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7546.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7546.json
@@ -1 +1 @@
-{"COMIRNATY": 2.635025098748173, "PEGASYS": 1.284037638644863, "SPIKEVAX": 1.382432583394609, "SUTENT": 1.419569164942869, "VAXZEVRIA": 1.395466050796282}
\ No newline at end of file
+{"ETANERCEPT": 134.3409973507636, "JARDIANCE": 6.726184593374055, "LATUDA": 20.2521963370098, "SIMPONI": 9.652839627506966, "STELARA": 7.683961622481625, "ZOSTAVAX": 5.551547721708837, "null": 0.7923680100611015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7547.json
index 1cb12a00b40..a3aed7ea79f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7547.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7547.json
@@ -1 +1 @@
-{"ABRAXANE": 2.1930768722299785, "ACTOS": 1.9333144633384247, "AFINITOR": 1.6583731813383864, "ALDARA": 3.323494639758008, "ANAKINRA": 1.65398432699881, "AUBAGIO": 1.3391291162050596, "AVAMYS": 1.8569346350998075, "AXITINIB": 2.0561812031397326, "AZATHIOPRINE": 1.101247180606464, "BENLYSTA": 3.2938905583168467, "BOSULIF": 1.6990309717199017, "BRAFTOVI": 2.0491935620544086, "CABOMETYX": 2.2747540871832346, "CAELYX": 1.0676704688280292, "CICLOSPORIN": 1.4432141363195254, "COAPROVEL": 1.5907907568908408, "COMIRNATY": 1.189741962785465, "CONTRAST": 6.911590898476638, "COSENTYX": 3.736584258574296, "COTELLIC": 1.9926127124448867, "ELIQUIS": 1.2029242592542224, "EMPAGLIFLOZIN": 5.47350059612092, "ENTYVIO": 1.1276631486612598, "ERBITUX": 2.270291866888404, "ERLEADA": 3.0769161763195068, "FIASP": 1.6453920665862647, "GARDASIL": 1.1980200298910364, "HUMIRA": 1.2246454654706214, "IBRANCE": 1.0215219557655515, "ICLUSIG": 1.6248276611781904, "INCIVO": 1.8615020316772013, "INLYTA": 1.0227191080700877, "IPILIMUMAB": 1.039235746664577, "IRESSA": 6.348554775618841, "JARDIANCE": 1.1870658774065943, "KEYTRUDA": 3.933132847427425, "MEKINIST": 1.6091769451459057, "MELATONIN": 2.2774617726156228, "MEPOLIZUMAB": 1.7016363388346232, "NEXAVAR": 1.0490590729122424, "OPDIVO": 7.958009716743746, "OPTIMARK": 10.175293435584846, "PANITUMUMAB": 12.844063465430075, "PANTOPRAZOLE": 1.9300238109070655, "PEGASYS": 1.4583173240412317, "PEGINTERFERON": 1.0981065933874432, "PEGINTRON": 2.459574525065867, "RINVOQ": 4.212365609405509, "ROACTEMRA": 1.4584041019215503, "SKYRIZI": 2.893564877162633, "SPIKEVAX": 1.631816588055039, "SPRYCEL": 1.275610602506021, "STELARA": 1.3576732647077911, "STIVARGA": 2.6989420433026377, "SUTENT": 2.813063745046134, "TAGRISSO": 5.413889254239975, "TREMFYA": 2.0899028626370044, "VAXZEVRIA": 1.9659735330369303, "VECTIBIX": 32.60552939365841, "VFEND": 1.1188723882269211, "VORICONAZOLE": 3.142508081839344, "XELJANZ": 1.6306881096779786, "XOLAIR": 1.1035977900750968, "ZELBORAF": 2.3144270772876645}
\ No newline at end of file
+{"ABILIFY": 29.53343900548627, "ARIPIPRAZOLE": 8.846077433684453, "INSULIN": 8.450617181705182, "OLANZAPINE": 34.30861950775119, "ZYPREXA": 45.67785530482576, "null": 0.7844630119421875}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7548.json
index 57c45c9b8a9..6f67beeb341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7548.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7548.json
@@ -1 +1 @@
-{"ACTRAPID": 13.122778890193228, "ALDARA": 23.49579280694612, "CANCIDAS": 18.629311331140155, "CICLOSPORIN": 1.9636073725306369, "COSENTYX": 1.5722977594093464, "IMIQUIMOD": 174.81077875704233, "KEYTRUDA": 1.8992888135465824, "LEVETIRACETAM": 2.03787929668052, "LEVOFLOXACIN": 2.2600491902214683, "METFORMIN": 57.99069923596083, "METHOTREXATE": 2.303265898630268, "NEXAVAR": 3.58359426885511, "STIVARGA": 3.8239177110882583, "TAMIFLU": 3.457178596653861, "null": 2.0997472573757374}
\ No newline at end of file
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7549.json
index 31bd33132b1..db46af29f02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7549.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7549.json
@@ -1 +1 @@
-{"ACTOS": 1.3865104411048907, "ADENURIC": 3.1840999384873645, "AERIUS": 1.111996461025279, "AFINITOR": 1.2967344482490666, "ALDARA": 2.4362292731836748, "ALIMTA": 1.6123023934513516, "AUBAGIO": 1.1452926720801584, "AZTREONAM": 8.08104651117738, "BOSULIF": 1.5963589242626728, "CABOMETYX": 2.4074806347671776, "CAELYX": 3.4631216770196502, "CANCIDAS": 1.609676432249362, "CAPECITABINE": 1.6230658704264604, "CAPRELSA": 5.543495736990219, "CASPOFUNGIN": 3.5865656506980783, "CHAMPIX": 1.2202426071298935, "CICLOSPORIN": 1.430064730179154, "COAPROVEL": 1.5097881503872457, "COMPLEMENT": 22.56718752593687, "CONTRAST": 6.165447605199485, "COSENTYX": 4.968453040818748, "COTELLIC": 5.075520784789844, "CUBICIN": 1.0552439513972758, "DARUNAVIR": 2.2729067107993752, "DEXAMETHASONE": 1.201106241629328, "DOCETAXEL": 1.2133748754596858, "DUPIXENT": 4.940260220829432, "EFAVIRENZ": 2.152465130373028, "EMEND": 1.8116664772189457, "ERLEADA": 3.586851519869861, "ESBRIET": 4.484367857591661, "EUCREAS": 3.014405639842455, "EVOLOCUMAB": 47.940157979314, "EXFORGE": 1.3475206355760474, "FLEBOGAMMA": 1.5832099578283214, "GALVUS": 3.789127149376613, "GLIVEC": 3.3793741361913217, "HERCEPTIN": 1.6862973294046046, "HUMAN": 1.1160549809912412, "HYDROCORTISONE": 14.6373037950837, "IBRANCE": 1.7274603929618308, "IBUPROFEN": 1.3252874388605873, "ICLUSIG": 6.776978661121519, "IDACIO": 11.894034104656086, "IMATINIB": 2.045808915975054, "IMIQUIMOD": 9.383746553014925, "INCIVO": 1.704538797116518, "INCRUSE": 1.493554888832349, "INLYTA": 2.672777614972349, "IRESSA": 3.332686353391652, "ISENTRESS": 1.3328956761064892, "JARDIANCE": 1.127486692055205, "KEPPRA": 1.3258955941668609, "KISQALI": 3.8624027475706058, "LEVOFLOXACIN": 1.7712480292999333, "LONSURF": 1.349132564689234, "METFORMIN": 9.748322001508733, "METHOTREXATE": 1.201185406706634, "MYCOPHENOLATE": 1.3702573812407393, "NEVIRAPINE": 13.705335866268175, "NEXAVAR": 6.737145521819704, "NINLARO": 1.7256066909442065, "OLYSIO": 2.2929879370282253, "OPTIMARK": 7.965240173412081, "PEGASYS": 1.285144557239798, "PEGINTERFERON": 1.6515842351539345, "PEMETREXED": 1.9569380862836037, "PRIVIGEN": 3.0262722299271774, "PROTOPIC": 12.041146880655416, "RAPAMUNE": 1.4182619204219789, "RENVELA": 60.35200244047112, "REVLIMID": 1.4162498362161364, "RINVOQ": 1.3337375596329346, "ROACTEMRA": 1.0111813790438504, "SIMPONI": 1.2159524793977974, "SKYRIZI": 4.724383334782908, "SORAFENIB": 2.8192660283382813, "SOVALDI": 1.057941708576869, "SPRYCEL": 1.0356382569198983, "STELARA": 2.2518044513179927, "STIVARGA": 9.657830387498988, "SUTENT": 6.4994912659254, "TAGRISSO": 1.709919446540009, "TAMIFLU": 2.3195155944269445, "TAXOTERE": 4.51448753622689, "THALIDOMIDE": 1.6256496575029098, "TREMFYA": 2.741272450974, "VECTIBIX": 2.359484520363897, "VFEND": 2.395845571748475, "VOTRIENT": 1.3985718853851796, "XELODA": 1.4544355159623317, "ZELBORAF": 4.663787839091613, "null": 1.6719082641815968}
\ No newline at end of file
+{"ALLI": 1080.051204159216, "CANNABIDIOL": 132.0096209278199, "GARDASIL": 21.41090238761431, "ROTASHIELD": 1116.1260303304462, "null": 2.3173684856592693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/755.json
index aa0444682d7..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/755.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/755.json
@@ -1 +1 @@
-{"AFINITOR": 6.171036234868677, "CIMZIA": 1.3940679351246592, "CYTARABINE": 3.7276568503251672, "ELIQUIS": 1.6335309199867043, "HIZENTRA": 10.291454376890655, "HUMALOG": 1.3620788231061145, "PEGASYS": 2.232197470738288, "SIMPONI": 2.091746329783416, "XELJANZ": 1.8633380537687076, "XOLAIR": 3.3041485295367634}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7550.json
index 61e949e67d7..22b734305b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7550.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7550.json
@@ -1 +1 @@
-{"CONTRAST": 175.33973903413334, "OPTIMARK": 1003.5737319449272}
\ No newline at end of file
+{"BEOVU": 33.85487800279317, "COMIRNATY": 0.4135037748242318, "EYLEA": 74.87729792815857, "JETREA": 562.3379355361022, "LANTUS": 1.489577352339856, "SPIKEVAX": 0.3552471644419558, "TOZINAMERAN": 2.2822765888010004, "VAXZEVRIA": 0.7737322345987955, "VIAGRA": 5.967008577651318, "null": 0.914070605654044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7551.json
index 74b77486609..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7551.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7551.json
@@ -1 +1 @@
-{"ANAKINRA": 8.410424845715989, "BRAFTOVI": 4.60250612929561, "CABOMETYX": 2.577923457609308, "CAPECITABINE": 7.53154859761381, "CETUXIMAB": 25.5101441558486, "CONTRAST": 40.31965496019155, "COSENTYX": 5.682529090247976, "ENTRESTO": 1.6768358248368218, "ERBITUX": 28.77203524874415, "FORXIGA": 2.224156203732873, "HERCEPTIN": 3.87366899550238, "HYDROCORTISONE": 6.2804794138788855, "IBRANCE": 1.481004556082168, "IRESSA": 8.94937851549259, "JARDIANCE": 5.790524039529504, "NEXAVAR": 11.052755173513928, "OPTIMARK": 10.138605314112649, "PEGASYS": 3.6001088599828157, "RIBAVIRIN": 3.4608382545625664, "SIMPONI": 2.0465736403951573, "STELARA": 1.5126368819146407, "STIVARGA": 14.26684554132523, "SUTENT": 15.582741294057357, "TAGRISSO": 16.32960554174431, "VECTIBIX": 47.82367735227727, "VOTRIENT": 1.677964507326964}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7552.json
index cf218bc2b60..bd8b509c94b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7552.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7552.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 241.16165023190663}
\ No newline at end of file
+{"null": 4.0041722347359805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7553.json
index 1c2ef96b4b5..1d77a09e7ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7553.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7553.json
@@ -1 +1 @@
-{"MEPOLIZUMAB": 53.02451967239688, "NUCALA": 16.48256749082065, "OMALIZUMAB": 20.834120037371957}
\ No newline at end of file
+{"null": 1.0149738578763543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7554.json
index 9c3f16667c9..1b5cab109ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7554.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7554.json
@@ -1 +1 @@
-{"CICLOSPORIN": 17.9793872311801}
\ No newline at end of file
+{"BORTEZOMIB": 102.2879728018637, "BUSULFAN": 30.58992216234013, "CICLOSPORIN": 12.679210710726757, "CRIZOTINIB": 604.1764313162163, "SPINRAZA": 58.59525912964613, "SYNAGIS": 85.09869161671082, "null": 0.3269726995807561}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7555.json
index 03a7b31ce0a..c4ec764f306 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7555.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7555.json
@@ -1 +1 @@
-{"ALISKIREN": 11.389322364990765, "AUBAGIO": 1.1534738358665595, "BENLYSTA": 1.3742732795844383, "BRILIQUE": 6.427144795444262, "CICLOSPORIN": 1.4372790367768704, "CLOPIDOGREL": 3.939928753270861, "COSENTYX": 3.8344653786538543, "ELIQUIS": 6.655293447088898, "ENBREL": 1.5937951004256123, "ENOXAPARIN": 3.4174868880049534, "HYDROCORTISONE": 3.405066625463615, "JAKAVI": 2.961791512905184, "LIXIANA": 25.59641644629596, "NEXAVAR": 1.1200311145191724, "NPLATE": 5.2744455099479, "OCALIVA": 12.113433842089394, "OMALIZUMAB": 2.0351153344175783, "PLAVIX": 5.331956820961318, "RENVELA": 300.8721480257964, "SUTENT": 3.2628695218153405, "TREMFYA": 3.1937057501170965, "VAXZEVRIA": 1.794932944168309, "XARELTO": 8.552661202606576}
\ No newline at end of file
+{"BYETTA": 17.248697992406434, "JANUMET": 18.26491361104893, "NEXAVAR": 25.96536125872216, "STIVARGA": 24.28542944959026, "null": 0.1441648240278312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7556.json
index 851e00f55aa..36ab108ff9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7556.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7556.json
@@ -1 +1 @@
-{"ALIMTA": 6.506928888966977, "BEVACIZUMAB": 2.801901253308261, "BRAFTOVI": 5.37626273244945, "BUSULFAN": 2.7998063634887425, "CAELYX": 9.01758605148926, "CICLOSPORIN": 4.061092736016876, "CONTRAST": 82.6334529674112, "COSENTYX": 2.1340577362344697, "EMEND": 12.205053323347792, "HYDROCORTISONE": 14.925828477450448, "LEVOFLOXACIN": 3.136375666034769, "OPTIMARK": 98.62015591298464, "PEGINTERFERON": 2.8590961768122565, "PEMETREXED": 7.596153956270079, "ZOSTAVAX": 1.0071985780328854, "null": 1.751778711505075}
\ No newline at end of file
+{"null": 0.324221252742902}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7557.json
index c266d566ecb..e08bb1863fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7557.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7557.json
@@ -1 +1 @@
-{"CICLOSPORIN": 1.0300286378267969, "CONTRAST": 237.54789074649744, "COSENTYX": 2.362568881825132, "NEXAVAR": 3.13637128543387, "OPTIMARK": 432.90689983110553, "SUTENT": 3.940438312547662}
\ No newline at end of file
+{"AFINITOR": 16.677758887778452, "BYETTA": 10.333741608504498, "CABOMETYX": 12.397178295566626, "FASLODEX": 7.958295671219209, "JANUMET": 8.67162167824525, "JANUVIA": 13.121399701689672, "MEKINIST": 14.582469653935346, "NEXAVAR": 43.63209954533655, "PEMBROLIZUMAB": 16.599441420957305, "SORAFENIB": 69.905760963194, "STIVARGA": 14.871516198932746, "VOTRIENT": 11.730257387447825, "null": 0.225329737699916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7558.json
index 8a12f7dbb22..c919d1942fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7558.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7558.json
@@ -1 +1 @@
-{"OPTIMARK": 38.29635548342187, "null": 1.0807776674545309}
\ No newline at end of file
+{"null": 0.2198236407919148}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7559.json
index abd9c33c0b4..25af3058a5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7559.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7559.json
@@ -1 +1 @@
-{"null": 2.158702033383775}
\ No newline at end of file
+{"ABEMACICLIB": 81.60225083279639, "ABRAXANE": 67.35189139787303, "AFINITOR": 29.471351298415268, "ALIMTA": 1.382691488590421, "ALPELISIB": 86.4907984598958, "ARANESP": 0.6937515401080419, "AVASTIN": 4.211097455902413, "BEVACIZUMAB": 7.592950924618542, "BYETTA": 1.7221823267092855, "CABAZITAXEL": 76.50284239364831, "CABOMETYX": 16.25920264966424, "CAELYX": 3.441742769172808, "CAPECITABINE": 37.33983746186392, "CELECOXIB": 1.8756022327230248, "CELLCEPT": 0.7101206408737193, "CICLOSPORIN": 0.4998219444653763, "COMIRNATY": 0.0203129368214133, "COSENTYX": 0.324016625222396, "DABRAFENIB": 10.48483944623639, "DENOSUMAB": 63.03282663313394, "DEXAMETHASONE": 2.385064603320868, "DOCETAXEL": 18.2038678386517, "ELIQUIS": 0.2492255402072658, "ENZALUTAMIDE": 21.148135323764144, "ERIBULIN": 25.38961047309413, "ERLEADA": 13.247050129787748, "EVEROLIMUS": 44.916092013069736, "FASLODEX": 58.58671178279609, "FORSTEO": 1.6836412632215687, "FULVESTRANT": 78.40405213224157, "GEFITINIB": 35.13422829398389, "GLIVEC": 3.703569971895906, "HERCEPTIN": 8.710863335773325, "IBRANCE": 3.5400524514929868, "IPILIMUMAB": 1.7365293471733652, "IRESSA": 24.143152079819867, "IRINOTECAN": 5.862733569731827, "JANUMET": 2.175860393469856, "JANUVIA": 2.559705449641625, "JEVTANA": 10.591024199035726, "KEYTRUDA": 0.7126706983124954, "KISQALI": 37.6961749525868, "KYMRIAH": 1.9708181309324615, "LYNPARZA": 7.85483579204389, "MEKINIST": 9.652613631305078, "METHOTREXATE": 1.068264780124453, "NEULASTA": 2.0120600764763124, "NEXAVAR": 9.928395767594251, "NUBEQA": 28.788696981352857, "OLAPARIB": 14.800626475506084, "OPDIVO": 3.940960003961727, "OSIMERTINIB": 19.71399934239578, "PACLITAXEL": 13.182002823954797, "PAZOPANIB": 12.616916336947613, "PEMBROLIZUMAB": 1.438146295456651, "PEMETREXED": 3.4453514551195266, "PLUVICTO": 24.338396053255607, "RIBAVIRIN": 1.0304666920630992, "RIBOCICLIB": 77.19685287946722, "SORAFENIB": 8.459648334480317, "STIVARGA": 4.69540707373648, "SUTENT": 0.5796305374842312, "TAGRISSO": 16.023886140613364, "TRODELVY": 4.608094214969409, "VOTRIENT": 6.969653136969008, "XGEVA": 23.43139547256248, "XOFIGO": 106.1885235553158, "XOLAIR": 0.370976494618509, "XTANDI": 9.678539324149195, "ZOLEDRONIC": 29.374429379307216, "ZOMETA": 20.61406513089984, "null": 0.2779635849040427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/756.json
index 8aff7d1307a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/756.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/756.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7234952272323931, "CYMBALTA": 2.3927159187112976, "ELIQUIS": 1.572675628206007, "EXJADE": 6.109512861854927, "GARDASIL": 1.6347843421313322, "HYDROCORTISONE": 11.130338020192449, "KEPPRA": 2.074177574851125, "SPIKEVAX": 1.0697687341895588, "XELJANZ": 1.182334542347179, "null": 1.206784403242216}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7560.json
index 080a1d5d9ff..67f696161bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7560.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7560.json
@@ -1 +1 @@
-{"COVID19": 1.88754477117673}
\ No newline at end of file
+{"BEVACIZUMAB": 31.496876905278054, "BLINATUMOMAB": 317.92045073071745, "FASLODEX": 21.753073065422253, "MEKINIST": 22.575729946073945, "XOFIGO": 112.14775325467676, "null": 0.2374957573196106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7561.json
index fcca4ec331d..6bc69b1602c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7561.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7561.json
@@ -1 +1 @@
-{"BELIMUMAB": 120.83288024406104, "CONTRAST": 325.4943185846071, "HUMIRA": 3.733315474051074, "INSULIN": 2.5252735423438306, "NEXAVAR": 1.14641898051387, "OPTIMARK": 465.0880855715105, "STIVARGA": 7.926535035729247}
\ No newline at end of file
+{"FASLODEX": 42.91316863547268, "FULVESTRANT": 129.83334536743334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7562.json
index fa6e1f5a21a..04362346ab6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7562.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7562.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 8.176515840480876, "BENLYSTA": 3.23189915070601, "CICLOSPORIN": 4.12829917775097, "CIMZIA": 2.173299914758889, "COSENTYX": 2.7954161507559085, "CYTARABINE": 2.941933707968871, "ENBREL": 1.6897809675674675, "ENTYVIO": 3.63556538695333, "HIZENTRA": 7.779624734117752, "HYDROCORTISONE": 16.482734146931246, "IBRANCE": 1.1253322758505535, "LEVOFLOXACIN": 2.540034895548595, "MEPOLIZUMAB": 1.7062123060332952, "MYCOPHENOLATE": 6.338628070887749, "NEULASTA": 3.108887215642873, "NEXAVAR": 1.5650665549540443, "OMALIZUMAB": 1.688317461122386, "OPSUMIT": 2.250306152536794, "PEGASYS": 2.1935926577847207, "PEGINTRON": 1.3396717901533914, "PEMBROLIZUMAB": 3.2701089129512866, "ROACTEMRA": 8.288503732025632, "SIMPONI": 6.178335242931534, "STELARA": 3.601260673925592, "XELJANZ": 5.163054535036357, "XOLAIR": 3.342033417534267, "ZOSTAVAX": 2.3122884353416806}
\ No newline at end of file
+{"ABRAXANE": 13.197444504172031, "AFATINIB": 54.04114445315533, "AFINITOR": 16.831610834294263, "ALECTINIB": 68.20092214816468, "ALIMTA": 2.985369263592658, "ALPELISIB": 24.052704377612688, "ARANESP": 0.7036983311657947, "AVASTIN": 5.837199414939609, "BEVACIZUMAB": 8.101445073977075, "BRAFTOVI": 2.738881113488303, "CABOMETYX": 9.842122997169472, "CAPECITABINE": 23.184664464638796, "CICLOSPORIN": 0.4733714310207209, "COBIMETINIB": 20.20165330636985, "COMIRNATY": 0.020473650885899, "COTELLIC": 16.145387217005425, "DABRAFENIB": 74.25310461855811, "DENOSUMAB": 6.587491386229211, "DEXAMETHASONE": 1.286298865872032, "DOCETAXEL": 9.548306702064526, "ELIQUIS": 0.3827725902801753, "ERIBULIN": 29.157739427233377, "EVEROLIMUS": 5.909263629848896, "FASLODEX": 8.37805200645075, "FULVESTRANT": 10.43236062766184, "GEFITINIB": 137.6437376626633, "HALAVEN": 6.281793230317255, "HERCEPTIN": 29.56260290571279, "IPILIMUMAB": 17.19086188377956, "IRESSA": 80.0331746628135, "IRINOTECAN": 5.107361687359404, "JANUMET": 1.7197728873653613, "KEPPRA": 0.885515811483287, "KEYTRUDA": 1.48261709185143, "KISQALI": 6.32742206755942, "KYMRIAH": 2.8065009163255565, "LEVETIRACETAM": 0.7422813442287953, "LONSURF": 2.7283763054667407, "LYNPARZA": 15.60927396701696, "MEKINIST": 82.49791418944575, "METHOTREXATE": 0.8375966271252266, "NEULASTA": 3.3168553549386783, "NEXAVAR": 4.810446488160231, "NPLATE": 2.2319180727125825, "NUCALA": 0.6237816288102341, "OLANZAPINE": 0.455710565749068, "OLAPARIB": 13.141729510807032, "OPDIVO": 13.022718873683932, "OSIMERTINIB": 67.20668007534422, "PACLITAXEL": 8.477027558357051, "PAZOPANIB": 17.219248089598665, "PEMBROLIZUMAB": 2.047833824749328, "PEMETREXED": 6.874710134936829, "PERJETA": 10.500135282061494, "PERTUZUMAB": 16.292755740890993, "RIBOCICLIB": 6.822928870819823, "RUBRACA": 9.00918446382834, "STIVARGA": 10.325037494890625, "SUTENT": 0.5195181099368512, "TAFINLAR": 35.97684734159338, "TAGRISSO": 50.12358179331599, "TRODELVY": 31.637125528548697, "VEMURAFENIB": 27.65001307014291, "VIAGRA": 1.369335210284815, "VOTRIENT": 13.856136011628116, "XOFIGO": 13.789509431424143, "XTANDI": 2.042302060067424, "YERVOY": 44.140995296166736, "ZELBORAF": 38.98943047378976, "null": 0.220990105814532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7563.json
index 942affbde63..41285cf275e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7563.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7563.json
@@ -1 +1 @@
-{"ARAVA": 1.2241049415476355, "CICLOSPORIN": 3.912370812095685, "COSENTYX": 3.938117823531039, "HUMALOG": 1.606046529293882, "KEPPRA": 1.3963869082887688, "LANTUS": 1.068895553776276, "LEVOFLOXACIN": 5.488724777352484, "PEGASYS": 1.1344734039914104, "STIVARGA": 3.837779109460167, "SUTENT": 2.564304644407424, "null": 1.895986284656385}
\ No newline at end of file
+{"AFINITOR": 48.22864251164216, "FULVESTRANT": 65.46013638181599}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7564.json
index f1b73dee705..251ea979a9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7564.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7564.json
@@ -1 +1 @@
-{"AIMOVIG": 1.318378502140363, "ALDARA": 17.70122601436196, "BUPRENORPHINE": 4.579212984235571, "CIMZIA": 1.3196075802421654, "COSENTYX": 1.207922264711409, "ENTYVIO": 1.976445024654011, "EVRA": 18.608065985300453, "HUMIRA": 1.0148927047644458, "HYDROCORTISONE": 10.504449747979775, "IBRANCE": 1.030723026044138, "IBUPROFEN": 1.05840429941715, "JARDIANCE": 1.356294977428594, "MEPOLIZUMAB": 1.134176637508993, "OPSUMIT": 1.1283392838261448, "PEGASYS": 1.5303119736583009, "RINVOQ": 1.3928606242960813, "SHINGRIX": 2.087154532336783, "SUTENT": 2.930000802186153, "ZOSTAVAX": 1.5696991538362897, "null": 1.9318004464463832}
\ No newline at end of file
+{"CAPECITABINE": 85.99277676160573, "FASLODEX": 43.01452755606432, "null": 0.3243594459766253}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7565.json
index b1fab2692f1..2c8710ccabb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7565.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7565.json
@@ -1 +1 @@
-{"ARAVA": 1.9583495789483247, "AZATHIOPRINE": 2.694060611014957, "BENLYSTA": 2.3359975287312174, "BUPRENORPHINE": 1.125025576544948, "CLOPIDOGREL": 1.3765372946392127, "COLLAGENASE": 564.5997339138858, "CYMBALTA": 3.4797844061269347, "ELIQUIS": 7.685870144808694, "FORXIGA": 1.6370128444400718, "GARDASIL": 2.081268315813245, "HEMLIBRA": 15.78821221592371, "HIZENTRA": 1.778548704989951, "HUMALOG": 1.3706806035975223, "HUMIRA": 1.0696426320222807, "IBUPROFEN": 4.167067591809862, "KEPPRA": 3.058219787818623, "LANTUS": 1.4481743352168237, "MEPOLIZUMAB": 3.9734039957580776, "METHOTREXATE": 4.488539051743943, "MICARDIS": 2.3016414544571653, "NUCALA": 2.0639544237429783, "PEGASYS": 2.036222775639738, "PEGINTRON": 1.5510676791048488, "PLAVIX": 1.4274272446633929, "REMICADE": 4.9932190871523705, "REVATIO": 2.469501024733876, "RIBAVIRIN": 3.022576464560005, "RITUXIMAB": 2.005542838379549, "SIMPONI": 1.510228694911257, "SUBOXONE": 2.763378487992594, "TAMIFLU": 1.2158057119944592, "TRELEGY": 1.495638807753007, "XELJANZ": 2.1743684834052988, "XIAPEX": 81.29900011033402, "XTANDI": 1.0255702231077723, "XYREM": 4.640391406402893, "ZOSTAVAX": 1.2781287603939384, "ZYPREXA": 1.867187582752297, "null": 1.3090215793794655}
\ No newline at end of file
+{"null": 0.2636835288886316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7566.json
index 350a7545d15..8293401f006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7566.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7566.json
@@ -1 +1 @@
-{"ABACAVIR": 1.387816695108497, "ALDARA": 4.547923062012956, "ALEMTUZUMAB": 1.0273622365804478, "AMIKACIN": 3.640030679547249, "APIDRA": 1.04495655805896, "APREMILAST": 1.566503699878093, "ASPARAGINASE": 1.7382835951133473, "AUBAGIO": 1.314151599125547, "AZATHIOPRINE": 2.675930361005156, "BASILIXIMAB": 4.000702097071331, "BELIMUMAB": 4.764061773365795, "BENLYSTA": 2.184004233537326, "BIKTARVY": 2.11391998122753, "BRAFTOVI": 1.0802962493615182, "BUDESONIDE": 6.900106337972303, "BUPIVACAINE": 1.6091808396087812, "CABOMETYX": 1.018048123129029, "CAELYX": 2.308551366460995, "CANCIDAS": 4.224056028500778, "CASPOFUNGIN": 5.240745149143815, "CELECOXIB": 2.9734036878540904, "CETUXIMAB": 4.72614953093795, "CICLOSPORIN": 6.12849593283056, "CLOPIDOGREL": 1.001913793269931, "COAPROVEL": 1.4929243909686705, "CONTRAST": 6.945824595197582, "COSENTYX": 8.08071623801856, "COTELLIC": 2.48213174438987, "CUBICIN": 1.7657067842974594, "CYTARABINE": 2.172306088148208, "DEXAMETHASONE": 2.0889860783053176, "DOLUTEGRAVIR": 4.152409441463069, "DOXORUBICIN": 1.6528683393910075, "EFAVIRENZ": 12.2005873435129, "EMEND": 2.7789558861475787, "ENBREL": 1.1499986211749835, "ENOXAPARIN": 2.6470272167276545, "ERTAPENEM": 18.363471439040357, "ESBRIET": 1.0608357084216662, "FILGRASTIM": 2.3315305593421614, "FYCOMPA": 2.007819986359565, "GALVUS": 1.963099089309985, "HIZENTRA": 1.4314665827383586, "HUMAN": 1.1899383444543734, "HUMIRA": 2.221126364538839, "HYDROCORTISONE": 4.589618615293853, "IBRANCE": 1.1840584958591314, "IBUPROFEN": 1.6464161022849255, "ICLUSIG": 2.024141604145083, "IMIQUIMOD": 11.612426866497596, "INCIVO": 3.320614504559782, "INLYTA": 2.9740811126629665, "INSULIN": 1.0467561052305268, "IRINOTECAN": 1.0577364690663789, "JAKAVI": 2.501804836405108, "KISQALI": 1.521466791819075, "KYMRIAH": 1.226108584934625, "LAMIVUDINE": 9.466962784844132, "LEFLUNOMIDE": 2.3151985521192997, "LEMTRADA": 1.4383252757977918, "LEVOFLOXACIN": 1.4223415535585806, "LYRICA": 1.0764950845657753, "MEKINIST": 2.5095559123046605, "MEPOLIZUMAB": 1.4140299588499508, "METHOTREXATE": 2.442156326896061, "MYCOPHENOLATE": 3.4356428215250565, "NEXAVAR": 2.8528256510139136, "NILOTINIB": 2.745255098152901, "NOT": 1.2818487241050829, "NUCALA": 1.362933447215711, "OCALIVA": 2.2192977404845484, "OMALIZUMAB": 1.8627465077837595, "OPTIMARK": 11.374394007831654, "PANTOPRAZOLE": 1.984200420616697, "PEGASYS": 1.5759497013636108, "PEGINTERFERON": 2.376360741241249, "PEMBROLIZUMAB": 1.2533083867177148, "QUTENZA": 4.076096657856376, "RINVOQ": 3.20011956906552, "RITUXIMAB": 1.0577160171574884, "ROACTEMRA": 1.4207901047573028, "RUXOLITINIB": 2.854450858334013, "SHINGRIX": 3.7751905352692336, "SIMPONI": 1.2189278502929737, "SKYRIZI": 3.2214622849295544, "SOLIRIS": 1.0873347873724624, "STELARA": 1.949620941173333, "STIVARGA": 1.4186855966135072, "SUTENT": 3.363606272604888, "TACROLIMUS": 3.007428543531706, "TASIGNA": 1.3852383481051689, "TREMFYA": 2.087699310849314, "UPADACITINIB": 8.410892218998722, "VECTIBIX": 5.616056866047897, "VORICONAZOLE": 3.1239454473472112, "XELJANZ": 2.1867895003365008, "XOLAIR": 2.280642946835563, "ZELBORAF": 4.029432384047933, "ZOSTAVAX": 2.1200552263884025, "null": 1.0881432915237266}
\ No newline at end of file
+{"NEXAVAR": 17.7977981189221, "null": 0.1935758078915073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7567.json
index 1c472909aaf..c08c5d7ecc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7567.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7567.json
@@ -1 +1 @@
-{"null": 4.087854129026545}
\ No newline at end of file
+{"AFINITOR": 23.88024146973297, "EVEROLIMUS": 201.56682743457355, "MEKINIST": 23.551612640014262, "VOTRIENT": 25.069343267375142, "null": 0.3539884921052368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7568.json
index 43b7925233f..63aaa9c8a78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7568.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7568.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 3.74788859673578, "ARAVA": 1.040578206177696, "AZATHIOPRINE": 3.2421426728743783, "BYDUREON": 10.135354899374036, "CAPECITABINE": 3.165823093519471, "CELLCEPT": 1.4701907474448832, "CICLOSPORIN": 10.966927843030064, "COSENTYX": 2.271506956394293, "CYTARABINE": 3.671883340394436, "DEXAMETHASONE": 2.876574846541846, "ENBREL": 1.3897495246098692, "FASLODEX": 2.422801549014618, "FORSTEO": 1.183539342597427, "HIZENTRA": 2.5646149742877262, "HUMALOG": 1.263873209233625, "HUMIRA": 3.278395838909885, "INSULIN": 3.798412793941041, "LAMIVUDINE": 6.266463227898819, "LANTUS": 1.0581783113516492, "LEVOFLOXACIN": 1.717916335871078, "MEKINIST": 3.649676029315638, "METHOTREXATE": 2.0753808446780506, "MYCOPHENOLATE": 7.927424619355481, "NEXAVAR": 1.1797767970156223, "OMALIZUMAB": 1.7057868952748658, "OPTIMARK": 15.225302075083167, "PEGINTERFERON": 2.8792148646658746, "SIMPONI": 1.704627116062236, "STELARA": 1.547398443632651, "ZELBORAF": 6.387952162329265}
\ No newline at end of file
+{"ABEMACICLIB": 45.60456660337498, "ABRAXANE": 33.89317051002639, "AFINITOR": 37.86024728044821, "AFLIBERCEPT": 14.41295635305149, "ALPELISIB": 54.324832692377214, "ARANESP": 0.4813882836002074, "ATEZOLIZUMAB": 6.000978098293316, "AVASTIN": 7.889221364724828, "BEVACIZUMAB": 21.029893162562253, "BYDUREON": 2.624150068864416, "BYETTA": 30.45572009179837, "CABAZITAXEL": 9.313540304646349, "CABOMETYX": 5.535941811701664, "CAELYX": 7.25386423540664, "CANNABIDIOL": 4.847550654733778, "CAPECITABINE": 35.044179480167394, "CELLCEPT": 1.007224805246047, "CIALIS": 3.038713415793136, "CICLOSPORIN": 0.4908984879876047, "CIMZIA": 0.1837328355945316, "COMIRNATY": 0.0209817897806614, "COSENTYX": 0.3391391432103426, "CRIZOTINIB": 15.414354655152296, "CYTARABINE": 0.4395294119934804, "DABRAFENIB": 13.449048807140931, "DENOSUMAB": 38.10326855860724, "DEXAMETHASONE": 0.3485044734718985, "DOCETAXEL": 13.09151542299708, "ELIQUIS": 0.4430655193456076, "ENTYVIO": 0.7063752605713274, "ERBITUX": 3.0853196008628085, "ERIBULIN": 35.45978175461751, "EVEROLIMUS": 49.40117682104076, "EXFORGE": 0.71261595053762, "EXJADE": 0.3802185549826554, "FASLODEX": 28.087636815661828, "FENTANYL": 0.4260290866721187, "FILGRASTIM": 2.8805693342087046, "FORSTEO": 0.3618285890473645, "FULVESTRANT": 52.17818804879387, "GEFITINIB": 24.86186010700512, "GLIVEC": 21.08590054413992, "HARVONI": 1.2704595820741575, "HERCEPTIN": 7.591623934907175, "IBRANCE": 0.9466522352376846, "IMATINIB": 27.095642301184416, "INFLIXIMAB": 3.302205441203484, "IPILIMUMAB": 2.2836365542458195, "IRESSA": 6.638260761547869, "IRINOTECAN": 15.957424143839791, "JAKAVI": 2.086661801475497, "JANUMET": 19.865374686238628, "JANUVIA": 17.51079759940971, "JARDIANCE": 0.2379122591945826, "JEVTANA": 3.2748000465265856, "KEPPRA": 0.2005915642384106, "KEYTRUDA": 0.4367756315915012, "KISQALI": 15.010978097019722, "KYMRIAH": 1.7912874635584306, "LANTUS": 0.4126634865912678, "LONSURF": 2.0058006572712084, "LUTATHERA": 17.84323881092934, "LYNPARZA": 6.364523857299057, "MEKINIST": 8.850456318573222, "METFORMIN": 3.755512816027257, "METHOTREXATE": 1.458836389207036, "NEULASTA": 1.7896483434801742, "NEXAVAR": 3.053413220496524, "OCTREOTIDE": 19.263468254725467, "OLAPARIB": 20.42826539110154, "OPDIVO": 3.0259874143756504, "OSIMERTINIB": 20.23584385119665, "PACLITAXEL": 8.32848896061637, "PANITUMUMAB": 18.687314237067422, "PANTOPRAZOLE": 1.6932062085920354, "PAZOPANIB": 10.105666365323083, "PEMETREXED": 2.6483612872406144, "PIQRAY": 9.271530529835005, "RIBOCICLIB": 44.954693367645305, "ROACTEMRA": 1.2786642539447766, "RUBRACA": 1.4733335160972518, "SIMPONI": 0.2464211244326173, "SORAFENIB": 6.502514645388471, "STELARA": 0.2485082489545605, "STIVARGA": 23.874126517292257, "SUTENT": 0.5157392486728556, "TAGRISSO": 7.575937267365127, "TRACLEER": 0.7740548604677298, "TRODELVY": 11.124902332275592, "VAXZEVRIA": 0.0081101435858814, "VECTIBIX": 19.326109349843605, "VICTOZA": 2.1663649974519754, "VOTRIENT": 6.395487341774149, "XELJANZ": 0.3069350331282621, "XELODA": 2.7565281006463964, "XOFIGO": 46.13333725429729, "XOLAIR": 0.3882910166388521, "XTANDI": 1.6980067701238728, "YERVOY": 3.2572757699936377, "ZOMETA": 5.033653834751213, "null": 0.3551956436927226}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7569.json
index ab68661c49b..d98b6e7b30e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7569.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7569.json
@@ -1 +1 @@
-{"AVASTIN": 1.5724330904172077, "BETAFERON": 29.481193262851587, "CASPOFUNGIN": 6.663962703438559, "CICLOSPORIN": 4.20122392047092, "CYTARABINE": 1.6795159423981512, "DEXAMETHASONE": 1.651024531400575, "EFAVIRENZ": 7.785549729167236, "ELIQUIS": 1.6210056240291906, "ENBREL": 13.67155809032594, "ENOXAPARIN": 17.228081001423956, "JAKAVI": 1.4533924699063543, "JARDIANCE": 1.0437022680306638, "NEXAVAR": 2.8949519108641115, "OPTIMARK": 4.203269806868773, "PEGINTRON": 3.44230165991304, "ROACTEMRA": 2.64555770468652, "TERIPARATIDE": 19.31323140631608, "null": 3.103904254665292}
\ No newline at end of file
+{"ABEMACICLIB": 37.63510260335623, "ABRAXANE": 27.63412771485676, "AFINITOR": 23.468528615121848, "ALPELISIB": 23.682241113965883, "ATEZOLIZUMAB": 10.14537471708999, "AVASTIN": 9.497411210528316, "AXITINIB": 8.410436113586357, "BEVACIZUMAB": 17.92804658710671, "BYETTA": 12.670800529081014, "CABOMETYX": 16.95571722064257, "CAPECITABINE": 20.82293444412094, "CELLCEPT": 0.8150598544087889, "CICLOSPORIN": 1.1900309793347017, "COMIRNATY": 0.0213479229167292, "CYTARABINE": 1.2903836873857957, "DABRAFENIB": 26.540211495558733, "DENOSUMAB": 15.123245947783852, "DEXAMETHASONE": 1.1037944600602545, "DOCETAXEL": 15.802891653483467, "ENBREL": 0.3761900493530014, "EVEROLIMUS": 41.68066664429985, "EXFORGE": 1.1904230531870688, "FASENRA": 1.13979292906319, "FASLODEX": 21.256895619078485, "FILGRASTIM": 3.06413385708991, "FORSTEO": 0.899938924127531, "FULVESTRANT": 30.166543374885133, "GEFITINIB": 36.13115434155291, "HERCEPTIN": 7.084990561471039, "IBRANCE": 0.7144891022157257, "INFLIXIMAB": 3.9776823642643135, "IPILIMUMAB": 6.438861607838036, "IRESSA": 8.774142922998356, "IRINOTECAN": 12.569450066620549, "JANUMET": 6.288914943920665, "JANUVIA": 7.623409756973144, "KISQALI": 16.481581218461102, "LONSURF": 2.995133353364316, "LYNPARZA": 3.5076420958540124, "MEKINIST": 14.760714822510034, "METHOTREXATE": 1.660132881966324, "NEULASTA": 2.1302622244131606, "NEXAVAR": 35.83003586033936, "OLAPARIB": 14.206373871789513, "OPDIVO": 3.818139964867101, "OSIMERTINIB": 20.150139670735104, "PACLITAXEL": 8.522404990230545, "PAZOPANIB": 47.94854878515119, "PEMBROLIZUMAB": 2.144551292427279, "PEMETREXED": 3.569441367978779, "REGORAFENIB": 39.116001822785215, "RIBOCICLIB": 36.50779916579864, "SORAFENIB": 30.543054872294285, "STELARA": 0.4515884441206333, "STIVARGA": 38.118732324234486, "SUTENT": 0.5407346203894899, "TAFINLAR": 10.738587887181808, "TAGRISSO": 6.587186732999116, "TRACLEER": 0.7781441519658697, "VECTIBIX": 8.126174606056066, "VIAGRA": 0.8104684179826496, "VICTOZA": 1.079949938612082, "VOTRIENT": 21.48019136910384, "XELJANZ": 0.2331076686848163, "XOFIGO": 20.96973600594865, "XTANDI": 0.7363679081583403, "YERVOY": 6.801163194434338, "ZELBORAF": 3.695946709795381, "null": 0.3069043733092473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/757.json
index f2a239f481f..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/757.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/757.json
@@ -1 +1 @@
-{"AIMOVIG": 23.18856569337211, "BRIVIACT": 86.71754002694297, "FYCOMPA": 22.55356930889413, "KEPPRA": 32.08587219672359, "LACOSAMIDE": 14.354161164108277, "LEVETIRACETAM": 16.286123382144673, "TOZINAMERAN": 1.3577018082535617, "VIMPAT": 26.866118462741696}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7570.json
index 812b394ddd5..7d189a56528 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7570.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7570.json
@@ -1 +1 @@
-{"CICLOSPORIN": 41.583784877478905}
\ No newline at end of file
+{"AFINITOR": 14.8963879754962, "ALIMTA": 1.7678777263976866, "AVASTIN": 6.804651773448049, "BEVACIZUMAB": 11.968733044344486, "BYETTA": 25.765809699884667, "CABAZITAXEL": 58.50279462978232, "CABOMETYX": 5.654454550740965, "CAELYX": 9.765847469944289, "CAPECITABINE": 27.85728891161123, "CELLCEPT": 2.5292154473754174, "CICLOSPORIN": 3.052038452414791, "COMIRNATY": 0.0590156070952114, "COSENTYX": 1.5714479806216308, "DABRAFENIB": 30.70553947850328, "DENOSUMAB": 56.437294754440025, "DOCETAXEL": 19.005162707479982, "ERLEADA": 6.249677927040783, "EVEROLIMUS": 24.873221042092617, "FASLODEX": 22.12534499300405, "FILGRASTIM": 5.741533166035016, "FULVESTRANT": 35.73387200321135, "GEFITINIB": 20.77716717434163, "HARVONI": 3.209468068523524, "HERCEPTIN": 7.10243917847237, "IBRANCE": 0.6603526824437734, "IPILIMUMAB": 4.478887375105418, "IRESSA": 13.49867076149224, "IRINOTECAN": 8.791000689432286, "JAKAVI": 2.304850779786278, "JANUMET": 16.90959720463442, "JANUVIA": 13.19697488441654, "KISQALI": 10.127196207173396, "LYNPARZA": 10.980605142565247, "MEKINIST": 18.561362913298435, "METHOTREXATE": 1.390628793006497, "NEULASTA": 2.6874863182482165, "NEXAVAR": 11.363897750905126, "OLAPARIB": 16.567588547047233, "OPDIVO": 4.581561098716215, "OSIMERTINIB": 19.914064423452132, "PACLITAXEL": 13.60697261388922, "PAZOPANIB": 18.11540227348305, "RIBOCICLIB": 40.90150870083818, "SPIKEVAX": 0.0328236885762469, "STIVARGA": 14.775683567287034, "TAGRISSO": 7.505266377899103, "TOZINAMERAN": 0.0899600332843088, "TRODELVY": 6.426408142046866, "VIAGRA": 3.624636339121254, "VOTRIENT": 6.438153289411878, "XOFIGO": 39.537118861861096, "XTANDI": 1.73333895083174, "null": 0.308049986854913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7571.json
index eb2300068a5..448042645ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7571.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7571.json
@@ -1 +1 @@
-{"ERTAPENEM": 151.6783115345313, "FASLODEX": 4.505935092948431, "FORSTEO": 2.112505025176776, "HUMALOG": 1.836665473580449, "JARDIANCE": 4.702889970042481, "SAXENDA": 6.3898460015954255, "null": 1.4790074360595076}
\ No newline at end of file
+{"AFINITOR": 4.5897413169678245, "ALIMTA": 9.324240708755696, "CAPECITABINE": 16.350004507027172, "DABRAFENIB": 59.98765145654069, "FASLODEX": 5.702916057930128, "GEFITINIB": 393.0899666966118, "IRESSA": 79.9672614942064, "IRINOTECAN": 23.142383242170787, "KEYTRUDA": 3.7097167425074993, "KYMRIAH": 17.4087257488375, "LYNPARZA": 10.914184310791969, "MEKINIST": 29.598609115839785, "OPDIVO": 5.882507387465225, "OSIMERTINIB": 313.46420020359267, "TAGRISSO": 80.14189619352831, "TRODELVY": 37.27705422132789, "XOFIGO": 26.33626632134654, "null": 0.1458928379088639}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7572.json
index eb0722beda4..e59c661231a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7572.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7572.json
@@ -1 +1 @@
-{"COSENTYX": 4.727968228820789, "OPTIMARK": 6.21524085008329, "XOLAIR": 5.874135795690657, "null": 2.025713421457311}
\ No newline at end of file
+{"null": 0.1873113400870538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7573.json
index d393b8879bb..86ecd33b5b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7573.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7573.json
@@ -1 +1 @@
-{"ARAVA": 1.5951401769735256, "BRAFTOVI": 10.492121021974182, "CELLCEPT": 4.7010893277027, "CICLOSPORIN": 7.077568314885081, "ELIQUIS": 1.0469307938371777, "ENBREL": 3.629311608002093, "GARDASIL": 5.957155275798578, "JAKAVI": 4.192325546590464, "NEXAVAR": 2.328719717175764, "STELARA": 4.004831047652977, "SUTENT": 3.456326112235839, "TAFINLAR": 56.4605016308825, "VEMURAFENIB": 195.36745689367575, "XELJANZ": 2.422605519046233, "ZELBORAF": 210.90135374181688, "ZOSTAVAX": 2.1999281008216918}
\ No newline at end of file
+{"null": 0.2316801762743038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7574.json
index 40107b9f991..f6cc30faebb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7574.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7574.json
@@ -1 +1 @@
-{"AFINITOR": 1.8065919949196092, "APIDRA": 1.7341900295578558, "CICLOSPORIN": 11.013931144418216, "CONTRAST": 75.81421967151907, "COSENTYX": 21.43006714705332, "ENTECAVIR": 14.51597262873656, "FASENRA": 2.3104415971961494, "HUMIRA": 3.4030039781789445, "LEFLUNOMIDE": 12.368737747488233, "METHOTREXATE": 3.074013773105626, "MYCOPHENOLATE": 5.740953783497286, "OMALIZUMAB": 13.453362506336688, "OPTIMARK": 41.0394106745083, "PEGINTERFERON": 6.559127872448173, "RENVELA": 346.5218211341869, "RINVOQ": 4.707851274598522, "SHINGRIX": 1.6700954263783878, "SKYRIZI": 19.38948657278382, "STELARA": 2.625866186484655, "TREMFYA": 5.009690559137988, "XOLAIR": 4.687672818951868, "null": 1.4600094618766817}
\ No newline at end of file
+{"BEVACIZUMAB": 56.616936146391545, "FASLODEX": 42.62108703170514, "null": 0.2518812479463225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7575.json
index b6b93e26fc6..5b5fd4591d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7575.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7575.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.0084283033524843, "AIMOVIG": 1.7445152513788824, "ALDARA": 11.193033437008417, "ALIMTA": 1.43395074200109, "AMELUZ": 85.10522020518985, "AUBAGIO": 1.2065118227122005, "AXITINIB": 2.818047522677273, "BETAFERON": 5.756386793338486, "BUPRENORPHINE": 1.1683789678570369, "BYETTA": 1.1194310202804352, "CAELYX": 4.8504101124817645, "CANNABIDIOL": 8.68376266470596, "CIMZIA": 1.1669796310991194, "COSENTYX": 3.124216619833983, "COTELLIC": 5.304706672132148, "ENTYVIO": 2.0301398975925653, "ERBITUX": 2.747788583345047, "ERLEADA": 6.59459687899933, "ESBRIET": 2.764968930462558, "EVRA": 4.00291753989474, "FASENRA": 2.451679171130251, "HERCEPTIN": 1.2680782639168833, "HIZENTRA": 2.4085911803181643, "HUMIRA": 2.029658386540922, "ICLUSIG": 1.9246284730778136, "IDACIO": 13.726564452481314, "IMIQUIMOD": 15.8383975256756, "INCIVO": 7.345750598595121, "IRESSA": 1.0829537429212717, "IRINOTECAN": 1.6332395060517524, "KEYTRUDA": 1.1521222888160316, "KISQALI": 2.3447665588577515, "LEMTRADA": 1.2412792587899035, "LEVEMIR": 3.3825724115326827, "MMRVAXPRO": 1.0188438174469847, "NEXAVAR": 3.3555249558991327, "NIMENRIX": 1.4335073387970534, "PEGINTERFERON": 2.527961094190675, "PEGINTRON": 1.7144246616365078, "PEMBROLIZUMAB": 1.8912852687148425, "PLEGRIDY": 5.581177612498316, "PRIVIGEN": 2.6762542278622803, "QUTENZA": 5.953423007477755, "ROACTEMRA": 4.599662227632093, "SAXENDA": 2.556655108922498, "SHINGRIX": 1.7684674177752588, "SORAFENIB": 4.758319618050393, "SPIKEVAX": 1.60575344082811, "STELARA": 1.1709647741220706, "STIVARGA": 2.5102875397970736, "TAGRISSO": 1.5269092116108716, "TEMOZOLOMIDE": 3.122019542635341, "VECTIBIX": 3.559296880273886, "XOLAIR": 1.2626401058386638, "ZELBORAF": 4.691425979020631, "ZYCLARA": 19.03068767252705, "null": 1.2967355697332394}
\ No newline at end of file
+{"AFINITOR": 17.949701841569926, "CABOMETYX": 55.94663760548036, "VOTRIENT": 22.25127026025585, "null": 0.5378166556132333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7576.json
index f870ad2691d..2ef0c0bd613 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7576.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7576.json
@@ -1 +1 @@
-{"COVID19": 2.860137711692208, "SPIKEVAX": 1.095117967362863, "SUTENT": 9.767066845952687, "TOZINAMERAN": 1.7378506551317243, "VAXZEVRIA": 1.6443690785764034, "XOLAIR": 7.046871761810538}
\ No newline at end of file
+{"ABRAXANE": 264.92328007524685, "AVASTIN": 19.367320539680247, "FASLODEX": 28.673534712106964, "FULVESTRANT": 33.37026756726263, "OLAPARIB": 142.24335558653013, "STIVARGA": 26.880117247900117, "null": 0.2559831701570337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7577.json
index 164d26b0b47..814ba80a0d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7577.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7577.json
@@ -1 +1 @@
-{"BUDESONIDE": 3.0074910778341315, "COSENTYX": 3.662838799088658, "GARDASIL": 10.109748111838549, "KALETRA": 11.070606604495058, "LOPINAVIR": 102.15224174216333, "METHOTREXATE": 4.224015695327822, "RITONAVIR": 159.8712553717871, "ZYPREXA": 4.268365028069802, "null": 1.9752105527662949}
\ No newline at end of file
+{"ABRAXANE": 49.41912303055205, "AFINITOR": 16.392788299494537, "AVASTIN": 8.407420830235772, "BEVACIZUMAB": 19.614781649694724, "BYDUREON": 3.4531664373773028, "BYETTA": 36.804315125463, "CABOMETYX": 5.542304053918134, "CAELYX": 32.53880288847138, "CAPECITABINE": 14.302328152877145, "DENOSUMAB": 26.360779971070592, "DOCETAXEL": 4.363921412940717, "FASLODEX": 14.680872262805131, "FULVESTRANT": 18.903484265608824, "GLIVEC": 34.11910597613456, "IMATINIB": 47.98240804771447, "IRINOTECAN": 23.411787841752663, "JANUMET": 32.588054146787705, "JANUVIA": 12.638973958185373, "LYNPARZA": 30.615660597831265, "MEKINIST": 10.155593579182266, "NEXAVAR": 11.751850587579357, "STIVARGA": 23.85734842534587, "VOTRIENT": 3.611108865173556, "null": 0.2754790538309228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7578.json
index 87dbc8be318..439c968904e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7578.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7578.json
@@ -1 +1 @@
-{"AIMOVIG": 2.013434367424705, "COSENTYX": 1.80680694984951, "HYDROCORTISONE": 11.491438452590453, "IBUPROFEN": 3.0143620528474298, "NEXAVAR": 2.223583113398042, "OPTIMARK": 30.4873981787522, "SPIKEVAX": 1.256013543412512, "STIVARGA": 7.935948615628367, "TOZINAMERAN": 1.4894483735613042, "XOLAIR": 3.0656877192478333, "null": 1.308162794672104}
\ No newline at end of file
+{"DOCETAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7579.json
index d73016b63f0..81300528574 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7579.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7579.json
@@ -1 +1 @@
-{"COVID19": 33.85643489306975, "TOZINAMERAN": 1.1917073604074513}
\ No newline at end of file
+{"AFINITOR": 19.00590443158831, "BEVACIZUMAB": 20.31589952636521, "DOCETAXEL": 12.563735743835828, "FASLODEX": 29.29441394990671, "FULVESTRANT": 58.40811912332766, "IRESSA": 33.3072167061144, "NEXAVAR": 9.428577915943851, "RIBOCICLIB": 69.54439858823935, "TAGRISSO": 27.48685934398338, "null": 0.1264936410137761}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/758.json
index de954706a0f..f8e7f2a1ff3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/758.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/758.json
@@ -1 +1 @@
-{"null": 1.140246523821261}
\ No newline at end of file
+{"GARDASIL": 18.15384972895468, "LEMTRADA": 139.0561226804252, "null": 0.5063454530123213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7580.json
index 1388f82f6ba..44c95ff74d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7580.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7580.json
@@ -1 +1 @@
-{"null": 14.090613018135617}
\ No newline at end of file
+{"FASLODEX": 46.87333645376855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7581.json
index 8dcac8c474d..fe52e4e485a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7581.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7581.json
@@ -1 +1 @@
-{"BUDESONIDE": 6.527595711168761, "FENTANYL": 3.685225804978232, "INSULIN": 9.396483262519974, "null": 6.845207254844766}
\ No newline at end of file
+{"ABRAXANE": 81.71431836821557, "AFINITOR": 21.59245823015479, "CAPECITABINE": 71.84643351762631, "DABRAFENIB": 77.26958700981854, "DOCETAXEL": 18.27070930325796, "EVEROLIMUS": 93.9978510593902, "FASLODEX": 49.9831245725674, "FULVESTRANT": 22.285745882372048, "MEKINIST": 34.28566162207151, "VOTRIENT": 7.616249199893995, "null": 0.2283251825340404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7582.json
index 7f539defb46..1ce1c16ce96 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7582.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7582.json
@@ -1 +1 @@
-{"null": 1.760684130622174}
\ No newline at end of file
+{"ADENURIC": 223.15815680677508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7583.json
index c46e8eac8c0..64908bd9c0f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7583.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7583.json
@@ -1 +1 @@
-{"AMELUZ": 91.4880189362023, "CONTRAST": 277.2311767228233, "OPTIMARK": 376.8937778286475}
\ No newline at end of file
+{"AFINITOR": 22.780305503711837, "BEVACIZUMAB": 7.483743528326173, "CABAZITAXEL": 65.03250451774127, "CABOMETYX": 12.99540661047675, "CANNABIDIOL": 37.158299060983616, "CAPECITABINE": 17.70889865359296, "DENOSUMAB": 61.8211325294319, "DOCETAXEL": 4.507200981192674, "ENZALUTAMIDE": 29.087245830294464, "EVEROLIMUS": 24.43880980660968, "FASLODEX": 31.36614352824106, "FULVESTRANT": 45.345687725419175, "IBRANCE": 2.542620954370455, "IRESSA": 11.360625521153604, "KISQALI": 35.82018120446954, "LYNPARZA": 10.113831741203056, "NEXAVAR": 16.876739383629452, "OLAPARIB": 40.95569226411904, "OPDIVO": 6.397980894324145, "PAZOPANIB": 23.342671409656152, "RIBOCICLIB": 37.56694829658316, "STIVARGA": 3.727047530953574, "TAGRISSO": 15.279311033087652, "VOTRIENT": 9.81058885925851, "XOFIGO": 72.39193727257059, "XTANDI": 5.766791176801762, "null": 0.4163383557865641}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7584.json
index 010a0e8a57c..f17d5160f14 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7584.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7584.json
@@ -1 +1 @@
-{"AFINITOR": 2.6620528436674338, "ALIMTA": 8.063454286184985, "ATEZOLIZUMAB": 34.12375280384661, "AVASTIN": 3.58210425107559, "BEVACIZUMAB": 17.51386657213315, "BUSULFAN": 14.14410952124942, "CABOMETYX": 13.87898244910454, "CAELYX": 23.52213784113808, "CAPECITABINE": 12.867081080569804, "CETUXIMAB": 139.9538247996285, "CICLOSPORIN": 1.1306282403992094, "COBIMETINIB": 179.22251002033113, "COTELLIC": 64.83311325050242, "CYTARABINE": 4.136057648139247, "DABRAFENIB": 23.845245938097648, "DEXAMETHASONE": 1.4381457633727155, "DOCETAXEL": 10.582405339649268, "ERBITUX": 32.44487531225435, "ERLEADA": 12.22907542915095, "FILGRASTIM": 7.554563587363239, "GEFITINIB": 48.854939917171336, "ICLUSIG": 5.531173261438314, "IMATINIB": 14.279151036202869, "INLYTA": 2.576019913306245, "IPILIMUMAB": 16.529410227504226, "IRESSA": 11.163595063292286, "IRINOTECAN": 32.088302184901224, "KEYTRUDA": 6.805813742651205, "KISQALI": 7.609922004740166, "MEKINIST": 6.592807795233899, "NEXAVAR": 19.81953950381269, "OPDIVO": 5.206369224972339, "OSIMERTINIB": 23.41604806846981, "PANITUMUMAB": 211.77842395279416, "PEMBROLIZUMAB": 24.193048356096604, "PEMETREXED": 16.728436226166863, "RIBOCICLIB": 10.701557439940547, "SORAFENIB": 49.06436858647975, "STIVARGA": 22.72282414744539, "SUTENT": 5.456806706048685, "TAGRISSO": 7.827041959957261, "TRAMETINIB": 61.042707162760856, "VECTIBIX": 206.9874088392349, "VEMURAFENIB": 96.46392986524911, "VOTRIENT": 4.251833848295403, "ZELBORAF": 30.54139831812801}
\ No newline at end of file
+{"BYETTA": 30.26868209216557, "CYTARABINE": 17.512252148486507, "JANUMET": 41.18890164786829, "JANUVIA": 14.738469939243368, "MEKINIST": 22.575729946073945, "NEXAVAR": 11.90556601257187, "null": 0.3081318935385139}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7585.json
index 5367b5ac970..57c33bb42ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7585.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7585.json
@@ -1 +1 @@
-{"null": 2.230215879687024}
\ No newline at end of file
+{"null": 0.4422738951752316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7586.json
index ff004e58bc5..afbc7f82acd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7586.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7586.json
@@ -1 +1 @@
-{"ACTOS": 2.8883106553108173, "AFINITOR": 1.702504651291062, "ALDARA": 10.211631803541431, "ALIMTA": 1.0711528397112722, "APIDRA": 1.9213574406787264, "ARAVA": 2.360997450507514, "AVASTIN": 1.3402822479886842, "BENLYSTA": 3.059968733501684, "BETAFERON": 2.697398202199367, "BEVACIZUMAB": 1.1797436844734048, "BOSULIF": 4.018673088317407, "CABOMETYX": 8.120795049257552, "CAELYX": 3.1359534856752225, "CELLCEPT": 2.135162797500428, "CICLOSPORIN": 3.51591796035077, "CIMZIA": 1.051558831754836, "COSENTYX": 1.0579027886487054, "DEXAMETHASONE": 1.0148712705698826, "DULAGLUTIDE": 5.764553801261481, "EFAVIRENZ": 5.316956296796837, "ELIQUIS": 1.0835577091766109, "EMPAGLIFLOZIN": 4.484422136846033, "ENBREL": 11.157963750771492, "EPIVIR": 2.2922558938832016, "ESOMEPRAZOLE": 16.85275523465684, "EXJADE": 1.9585324090692395, "FORSTEO": 1.1788577089699412, "FORXIGA": 1.688907852079135, "FULVESTRANT": 1.2356941091337328, "HIZENTRA": 1.0925169136131587, "HUMALOG": 2.8211535741436213, "HUMIRA": 1.1670334445952166, "IMIQUIMOD": 13.926701525783388, "INLYTA": 1.3353801098657463, "INSULIN": 1.422208292826865, "INVOKANA": 12.8946572172465, "IRESSA": 3.319389773588747, "JAKAVI": 2.114616105004522, "JARDIANCE": 3.098002610002665, "LAMIVUDINE": 2.3569622858840864, "LANTUS": 2.467221645283989, "LEFLUNOMIDE": 2.883054350028196, "LENVIMA": 3.817334753552463, "LEVEMIR": 3.069922889751004, "METHOTREXATE": 1.5497452345907117, "MIMPARA": 4.911313439209337, "MYCOPHENOLATE": 1.3535270048050922, "NEXAVAR": 5.04497692804652, "OPSUMIT": 1.605557849781002, "OPTIMARK": 9.160464757448402, "PEGASYS": 3.695326758901957, "PEGINTERFERON": 2.9075215145798965, "PEGINTRON": 2.3561383943173264, "PEMBROLIZUMAB": 1.5788771584078714, "PREGABALIN": 2.615663611675052, "RAPAMUNE": 2.95520767189949, "REVATIO": 1.778131532066788, "RIBAVIRIN": 1.1032870366107612, "RITUXIMAB": 1.5164331010227443, "ROACTEMRA": 6.271592681443155, "SIMPONI": 2.0077642042958206, "SORAFENIB": 6.50701368486814, "SPRYCEL": 1.0584339266688876, "STIVARGA": 4.842441244134107, "SUTENT": 3.538808031231361, "TAGRISSO": 2.032602812468616, "TASIGNA": 2.8546315394564266, "TRACLEER": 3.500765816671256, "VECTIBIX": 5.445784883195207, "VOTRIENT": 2.5809980532366565, "XELJANZ": 1.7523874066919838}
\ No newline at end of file
+{"AFINITOR": 24.127712662245457, "CAPECITABINE": 47.183346331412864, "DOCETAXEL": 46.5887650351626, "FULVESTRANT": 49.88382143570621, "null": 0.132392426711877}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7587.json
index abeec7ac583..32020e51797 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7587.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7587.json
@@ -1 +1 @@
-{"null": 1.35083983891539}
\ No newline at end of file
+{"FULVESTRANT": 182.29646371445895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7588.json
index a8a2f9ed3e9..37f565f86fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7588.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7588.json
@@ -1 +1 @@
-{"AIMOVIG": 1.103834340394921, "AMINOSALICYLIC": 4.33072139927645, "ARAVA": 2.835876712100337, "BENLYSTA": 1.8127370747454168, "COVID19": 2.413661523246591, "GARDASIL": 1.780661114809268, "LACOSAMIDE": 4.352616815764342, "MENVEO": 12.859470211311724, "MMRVAXPRO": 3.535789791234909, "NIMENRIX": 2.3841906876887364, "OPTIMARK": 2.7263703657254266, "SHINGRIX": 7.371041915438083, "SPIKEVAX": 2.1447636384831417, "STIVARGA": 2.887390944099752, "TOZINAMERAN": 2.104937946707614, "ZOSTAVAX": 1.7172873351195257}
\ No newline at end of file
+{"null": 0.8145643285262828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7589.json
index 52b4964ae80..587297e6e54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7589.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7589.json
@@ -1 +1 @@
-{"HYDROCORTISONE": 305.24579596888844, "IMIQUIMOD": 219.5377969668076, "STIVARGA": 12.210612125245008, "TOZINAMERAN": 1.070796728736813, "null": 1.3858644461367595}
\ No newline at end of file
+{"ABRAXANE": 30.71685088447018, "AFINITOR": 15.474885369391473, "AVASTIN": 5.871602254095089, "BEVACIZUMAB": 2.6264737549312365, "BUSULFAN": 5.173188000788712, "CABAZITAXEL": 22.82073299100337, "CABOMETYX": 2.8257224043979323, "CAPECITABINE": 8.695233229551581, "CICLOSPORIN": 0.9664060881810786, "COMIRNATY": 0.0905003921340453, "COTELLIC": 15.896274964634316, "CYTARABINE": 2.3328121215426005, "DABRAFENIB": 11.510920545905874, "DEXAMETHASONE": 2.123974894315249, "DOCETAXEL": 21.231728302693725, "ELIQUIS": 0.3970138179371259, "EVEROLIMUS": 12.058787052567316, "FASLODEX": 21.73320604899034, "FENTANYL": 1.04408308814502, "FULVESTRANT": 23.47055048563306, "GEFITINIB": 23.41666785477021, "GLIVEC": 10.76041380931471, "HERCEPTIN": 4.809965350308519, "IBRANCE": 1.343343051835445, "IPILIMUMAB": 4.070435754520704, "IRESSA": 31.50917039552248, "JANUMET": 4.676856486435232, "JANUVIA": 3.160345485280885, "JEVTANA": 10.476867917269118, "KEPPRA": 0.669340670471168, "KISQALI": 26.336611257910043, "LYNPARZA": 20.477532780170066, "MEKINIST": 23.39653800051764, "NEXAVAR": 6.630588623025816, "OSIMERTINIB": 21.220950133878887, "RIBOCICLIB": 18.504186471736244, "RITUXIMAB": 2.3201627114694903, "STIVARGA": 5.534298052188569, "SUTENT": 0.3365249850759513, "TAGRISSO": 19.640796287052037, "TEMOZOLOMIDE": 11.842009849091328, "TRODELVY": 15.85493451381507, "VOTRIENT": 17.38652411379557, "XOFIGO": 56.153072190287546, "XTANDI": 6.664261700612534, "YERVOY": 6.750475518621078, "ZELBORAF": 13.484747460593926, "null": 0.5181394439732546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/759.json
index 943391dc654..9c0eea8b99b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/759.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/759.json
@@ -1 +1 @@
-{"ABILIFY": 1.572307566768234, "AVAMYS": 3.592499070704044, "INFANRIX": 28.138576039174293, "KEPPRA": 2.688855080281759, "LATUDA": 4.740991880305043, "LEVETIRACETAM": 2.5115092688028566, "MMRVAXPRO": 7.923270583640497, "NOT": 14.291885322595691, "PREVENAR": 28.46206393260012, "PROQUAD": 110.610637420402, "ROTASHIELD": 218.14145827741063, "SPINRAZA": 5.350631067002635, "SUBOXONE": 1.6601587498874082, "null": 8.856395948699529}
\ No newline at end of file
+{"COMIRNATY": 4.237198194502826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7590.json
index ae814a69744..fc10060c978 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7590.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7590.json
@@ -1 +1 @@
-{"HEXYON": 634.1460256189082, "INFANRIX": 51.72130811301144, "MMRVAXPRO": 77.01037602335396, "NEXAVAR": 3.6028465880742018, "PREVENAR": 46.76304399660237, "SUTENT": 3.636546752956346}
\ No newline at end of file
+{"null": 0.9090954767196192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7591.json
index c04f07d81e8..b98566dd830 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7591.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7591.json
@@ -1 +1 @@
-{"ATRIPLA": 1.0684966038205836, "COSENTYX": 4.698107230938798, "HYDROCORTISONE": 54.00945368920078, "OPTIMARK": 12.567536580225786, "PEGASYS": 1.969057556389152, "null": 1.3922562938122}
\ No newline at end of file
+{"null": 0.64808008921029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7592.json
index 47dda47b315..3ac100e5078 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7592.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7592.json
@@ -1 +1 @@
-{"ATRIPLA": 2.408687156980318, "ELIQUIS": 3.237891432385267, "GARDASIL": 4.728530957616817, "SUBOXONE": 8.290320352565123, "null": 1.3027655404516345}
\ No newline at end of file
+{"CARMUSTINE": 162.38853222426616, "null": 0.5597866209721958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7593.json
index 72ac7a328d6..47808226410 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7593.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7593.json
@@ -1 +1 @@
-{"ABILIFY": 1.290356181067868, "ALENDRONATE": 109.38417176708874, "APIXABAN": 70.37482887395157, "ARIPIPRAZOLE": 1.7719934211514343, "AVAMYS": 17.295993368830857, "AVANDIA": 1.757725458015677, "AVONEX": 19.10013005312653, "BRILIQUE": 8.144419603436068, "BUDESONIDE": 1.055793393303909, "BUPIVACAINE": 3.3897731919806624, "BYDUREON": 1.7489316580498626, "BYETTA": 4.132514895121318, "CIALIS": 6.563518382862385, "CLOPIDOGREL": 3.421456930786577, "COSENTYX": 1.3525947775806724, "CYMBALTA": 1.6009505139781226, "DESLORATADINE": 8.043705822563235, "DULOXETINE": 5.096145714019685, "ELIQUIS": 2.977148651437226, "ENBREL": 1.2901711950347008, "ENTRESTO": 1.6920303676858317, "ESOMEPRAZOLE": 4.18688484368344, "ETANERCEPT": 15.490376288416511, "HUMALOG": 2.531347065786174, "INCRUSE": 4.356379543840764, "IRBESARTAN": 2.563521737044622, "JANUMET": 1.480912725221466, "JANUVIA": 1.422783667226288, "LANTUS": 1.0867035969180188, "LATUDA": 2.118349250164602, "LYRICA": 3.2712674102035946, "MELATONIN": 4.600863315791362, "MEPOLIZUMAB": 3.725102838325321, "NAGLAZYME": 9.126215317740336, "OLANZAPINE": 1.1320606065797023, "OMALIZUMAB": 1.4322348099927749, "OPTIMARK": 1.057610325958652, "PASIREOTIDE": 78.53406379154528, "PROPRANOLOL": 5.151297364672861, "REVATIO": 1.6394533915249974, "RINVOQ": 1.3984456100017613, "SOMATROPIN": 37.15198603838651, "SUBOXONE": 4.189922175011117, "TASIGNA": 1.0024904198869526, "TRULICITY": 1.1551616668930007, "VIAGRA": 2.697323635516661, "XOLAIR": 1.5480902589430892, "XYREM": 24.40824121628004, "ZOSTAVAX": 5.143442676131692, "ZYPREXA": 3.5518991829703337, "null": 1.0749178101278676}
\ No newline at end of file
+{"ABACAVIR": 2.146734443215766, "BRAFTOVI": 18.72576582039307, "CIALIS": 398.3852834812421, "CICLOSPORIN": 1.4284741417416325, "COBIMETINIB": 95.22920200409833, "COTELLIC": 15.604456715116802, "DABRAFENIB": 398.4923391902726, "IPILIMUMAB": 21.94798157927847, "KEYTRUDA": 2.8985133271412504, "MEKINIST": 184.69087549226515, "OPDIVO": 3.885011201384616, "TAFINLAR": 127.91629892137396, "TRAMETINIB": 432.5070243040728, "VIAGRA": 59.45174475157529, "ZELBORAF": 51.46286329880186, "null": 0.2097311106815003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7594.json
index 2339bdd6469..9e8543a1961 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7594.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7594.json
@@ -1 +1 @@
-{"SIFROL": 148.7369415378984, "null": 2.018703857925951}
\ No newline at end of file
+{"ABEMACICLIB": 107.1257911622265, "AVASTIN": 5.649345866355414, "BEVACIZUMAB": 9.871907193808552, "BYDUREON": 3.613277989593727, "BYETTA": 7.273380179448467, "CAPECITABINE": 9.274658337598597, "CLOPIDOGREL": 1.8932751600207929, "COMIRNATY": 0.0336097459355046, "ELIQUIS": 0.9232991106969264, "EPADERM": 756.3507176705792, "FASLODEX": 9.00727358121581, "FULVESTRANT": 12.258242032138185, "HERCEPTIN": 14.712173388250616, "IBRANCE": 1.833540089602432, "JANUMET": 5.386374721631019, "JANUVIA": 4.842037036549811, "LANTUS": 1.0516133777563637, "MEKINIST": 8.046668306986133, "NEXAVAR": 1.8131738214077624, "SIMPONI": 1.910844837082832, "SPIKEVAX": 0.1031035051646986, "STELARA": 1.521094290959116, "SUTENT": 0.8762835117619637, "VOTRIENT": 11.82295108728882, "XTANDI": 2.5766044654416627, "null": 0.7718008229199249}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7595.json
index 1ced67f2d97..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7595.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7595.json
@@ -1 +1 @@
-{"COVID19": 1.251514551358508, "CYMBALTA": 2.844849661934622, "KEPPRA": 2.7782502839505336, "METHOTREXATE": 7.311567416306866, "TOZINAMERAN": 1.8609520039732304}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7596.json
index 50d43c85aa1..0503dbac491 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7596.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7596.json
@@ -1 +1 @@
-{"ABILIFY": 1.5640454940834276, "ACLASTA": 2.056634791318324, "ADALIMUMAB": 1.4322287723856384, "ADENURIC": 1.214902777855043, "AGOMELATINE": 5.576274140013453, "AIMOVIG": 2.193179179637418, "APREMILAST": 5.225999522163675, "ARAVA": 1.204619897202717, "ARIPIPRAZOLE": 1.6576374639146223, "ARZERRA": 3.9228860020879495, "AVAMYS": 1.965036026617386, "BENRALIZUMAB": 1.2608739227808057, "BETAFERON": 1.0597007809869745, "BEXSERO": 1.075845909748632, "BIKTARVY": 4.857128596363057, "BRINTELLIX": 3.030216949939113, "BRIVARACETAM": 1.9085018290768567, "BRIVIACT": 3.0024006413297077, "BUPRENORPHINE": 1.087660022239059, "CANNABIDIOL": 1.1331067439171432, "CARBIDOPA": 1.0576705752602915, "CAYSTON": 17.36845551502997, "CHAMPIX": 5.167342683377534, "CHLORHEXIDINE": 7.730572410623604, "CIMZIA": 2.797161979512248, "CIRCADIN": 3.328391424298381, "COMIRNATY": 1.06545665457283, "CYMBALTA": 6.18770538779633, "DESCOVY": 1.745521697085893, "DESLORATADINE": 1.233819561460477, "DULOXETINE": 1.7748144326941435, "EDURANT": 10.351067834230673, "ELLAONE": 1.2102544358761989, "EMTRICITABINE": 1.4262421784439567, "ENTACAPONE": 1.8694273482677437, "ESMYA": 1.1202742596606692, "ESOMEPRAZOLE": 1.1595529139739595, "EVISTA": 1.074481978749337, "FAMPYRA": 3.9772654213152334, "FLUCELVAX": 1.5840731017315308, "FYCOMPA": 1.1822672181196072, "GARDASIL": 2.472838215558343, "GENVOYA": 1.960500991280118, "GLYCOPYRRONIUM": 2.3973991503472942, "HEMANGIOL": 21.843204118528053, "HEXYON": 5.602653087644858, "HUMIRA": 1.8355637358835035, "INFANRIX": 2.541040451407707, "INTELENCE": 2.466520317712088, "INTERFERON": 2.004626325889361, "ISENTRESS": 1.0281889217603497, "KAFTRIO": 6.284016319867672, "KEPPRA": 1.7206858557701503, "KIVEXA": 2.7056596780610738, "LATUDA": 1.3176932989662862, "LEVETIRACETAM": 1.1504890962465664, "LIXIANA": 1.0001580032400958, "LURASIDONE": 2.4417419319407294, "MELATONIN": 7.625431222602592, "MEPOLIZUMAB": 1.8453634298217905, "MMRVAXPRO": 1.1813360832132909, "NUCALA": 2.593641060892796, "OCALIVA": 1.512086913082992, "OCRELIZUMAB": 1.7183786773184495, "OMALIZUMAB": 1.805689310278329, "PEGINTERFERON": 1.1566918948725748, "POPPERS": 6.328261912149192, "PREVENAR": 1.1855904931884826, "PROLIA": 2.791366773875038, "RANEXA": 1.3962409533626896, "REAGILA": 3.797216342306744, "SEMAGLUTIDE": 23.535549495256504, "SIFROL": 5.621318224776958, "STALEVO": 1.084721826631884, "TIVICAY": 3.6675845786876895, "TRIUMEQ": 6.430904232321366, "TWINRIX": 1.6451249450174164, "VALDOXAN": 3.110988763167674, "VARENICLINE": 4.82867831410423, "VORTIOXETINE": 4.555933280981491, "XELJANZ": 1.109097523491593, "ZEJULA": 2.6855933521846715, "ZOSTAVAX": 2.257511875863736, "ZYPREXA": 1.009928712786047, "null": 1.173261729692903}
\ No newline at end of file
+{"AFINITOR": 10.200336495491236, "AXITINIB": 15.11998771999516, "CABOMETYX": 14.59420405941105, "EVEROLIMUS": 18.240195690993257, "INLYTA": 57.561952567542654, "NEXAVAR": 8.197947416268333, "PAZOPANIB": 52.539787273854216, "SORAFENIB": 30.86796027671447, "SUTENT": 207.66541267210232, "TORISEL": 46.4807089170371, "VOTRIENT": 26.658796092450817, "null": 0.1337787628078643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7597.json
index 978dbab2a14..416b984744d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7597.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7597.json
@@ -1 +1 @@
-{"ACLIDINIUM": 42.458103823346725, "AMINOSALICYLIC": 2.0674883309448844, "ANORO": 8.869511447141978, "APIXABAN": 68.5853692925921, "AVAMYS": 46.24329138886964, "AZATHIOPRINE": 3.64214162071811, "AZOPT": 61.5249815100347, "BENRALIZUMAB": 97.8165103138532, "BUDESONIDE": 25.56865674664422, "CANAGLIFLOZIN": 50.41984522865183, "CAYSTON": 244.8819808223313, "DESLORATADINE": 23.36322839179094, "DEXAMETHASONE": 2.0481557647160296, "DUPIXENT": 7.551327766714572, "ELIQUIS": 1.854402172539622, "ESOMEPRAZOLE": 2.448396840811888, "FASENRA": 2.431636024798509, "FLUTICASONE": 26.75472397787636, "FORSTEO": 1.4207742207131593, "GLYCOPYRRONIUM": 134.64073509343035, "HYDROCORTISONE": 4.125760092701747, "IBUPROFEN": 1.007179268652035, "INCRUSE": 18.40221145482263, "INSULIN": 6.922145763030374, "IRON": 7.178404982553513, "JANUVIA": 1.7051838882855053, "LIRAGLUTIDE": 137.19558870950686, "MEPOLIZUMAB": 93.50031023286404, "NUCALA": 65.7299016530361, "OMALIZUMAB": 6.094867262924109, "PANTOPRAZOLE": 9.535732436272411, "TELMISARTAN": 19.626837093032712, "TRELEGY": 3.219309590002695, "UMECLIDINIUM": 70.11035096154502, "VARENICLINE": 31.60622341915452}
\ No newline at end of file
+{"NEXAVAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7598.json
index 0ade75846f0..9caa024ebcf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7598.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7598.json
@@ -1 +1 @@
-{"COSENTYX": 143.69406594625357}
\ No newline at end of file
+{"STELARA": 16.56906856672948, "null": 0.6264936854158752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7599.json
index 0a0bc5d0890..323f9900566 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7599.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7599.json
@@ -1 +1 @@
-{"ABATACEPT": 55.90672885845112, "ADALIMUMAB": 6.681113163450791, "APIXABAN": 19.522213314584707, "APREMILAST": 11.305619946130903, "ARAVA": 6.351568711870869, "CELLCEPT": 8.224193024830127, "CHLORHEXIDINE": 165.0232517719273, "CIMZIA": 46.33495291967442, "DACLIZUMAB": 415.4554398077158, "ENBREL": 2.25174920970401, "FORSTEO": 7.760791120764014, "HUMALOG": 1.289030658026785, "TRULICITY": 2.4503251544825257, "XELJANZ": 1.1156574938244774, "ZOSTAVAX": 1.772942226376762}
\ No newline at end of file
+{"INVOKANA": 1190.3828331667223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/76.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/76.json
index e4961e6140a..694179a3464 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/76.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/76.json
@@ -1 +1 @@
-{"AIMOVIG": 16.437353676171643, "ARANESP": 1.7098968873557736, "BENLYSTA": 3.4356332218278096, "BENZODIAZEPINE": 5.040554654149069, "CARIPRAZINE": 26.793883643369128, "CLOPIDOGREL": 1.154220479724562, "COSENTYX": 7.912577665945781, "FENTANYL": 1.3973207109036303, "GLIBENCLAMIDE": 9.795380822874098, "IBUPROFEN": 1.874990708739466, "KEPPRA": 6.332085968901976, "LEVETIRACETAM": 1.0132891840962026, "MICARDIS": 1.3470541426201226, "NEULASTA": 5.244019986987424, "NINLARO": 5.489540689415383, "NUCALA": 3.5218586355888664, "QUTENZA": 15.709376464122007, "SIMPONI": 35.56048966732856, "STELARA": 6.574266998270634, "SUBOXONE": 5.538641579097947, "TESTOSTERONE": 12.133928462726663, "TREMFYA": 58.70039904379816, "TRULICITY": 1.0776868217469684, "VIMPAT": 4.240859210788143, "ZYPADHERA": 1.9337724727857728, "ZYPREXA": 1.2989358781627591, "null": 2.7179768189468825}
\ No newline at end of file
+{"ABACAVIR": 0.5309261146185899, "ABILIFY": 0.9951633891967911, "AERIUS": 3.144407056197952, "AIMOVIG": 1.7211460632316269, "APIDRA": 1.2785556375683156, "ARAVA": 0.2828076257765247, "ATAZANAVIR": 0.663824272533483, "ATRIPLA": 0.1535331873566856, "AUBAGIO": 1.8691255686778296, "BARACLUDE": 5.522991508505197, "BEDAQUILINE": 0.6294034563074421, "BENLYSTA": 1.7676422405261552, "BETAFERON": 2.312950445121351, "BIKTARVY": 1.1290536482493143, "BRINTELLIX": 0.6631027357550563, "BRIVIACT": 1.5723142577875973, "BUPRENORPHINE": 2.832749043401606, "BUVIDAL": 11.042530920582866, "BYETTA": 0.367379802002602, "CELLCEPT": 1.6901216507756291, "CETROTIDE": 41.36617298931657, "CHAMPIX": 0.7889815925319108, "CICLOSPORIN": 0.2213355192415951, "CIMZIA": 2.6889848605295485, "CINRYZE": 4.352654143550742, "COMBIVIR": 7.264560865183492, "COMIRNATY": 0.6706682772076743, "COSENTYX": 0.9918590017591972, "CYMBALTA": 2.48977824130413, "DARUNAVIR": 3.968520056780525, "DEXAMETHASONE": 0.2790936321832327, "DOLUTEGRAVIR": 3.1330095999477057, "DULOXETINE": 1.0074032086202287, "EFAVIRENZ": 16.75952185738349, "ELIQUIS": 0.0641706049516764, "ELLAONE": 11.008724546845963, "EMTRICITABINE": 2.942096135529341, "ENOXAPARIN": 2.1357151244559334, "ENTECAVIR": 3.2826850280997317, "ENTYVIO": 3.2573842129482307, "EPCLUSA": 2.4904397223012094, "EPIVIR": 2.824132659772705, "ESMYA": 4.303600445537499, "EVRA": 10.26560903728218, "EXFORGE": 0.3843446938782571, "EXJADE": 0.3447821209629763, "FAMPYRA": 0.8066014262283201, "FASENRA": 1.1095569605093436, "FENTANYL": 0.2297404009009219, "FIASP": 1.545631444343814, "FOLLITROPIN": 44.88515405519594, "GARDASIL": 4.204782983496123, "GENVOYA": 4.043792838386082, "GONALF": 15.42175663392469, "HIZENTRA": 0.4226925750139985, "HUMALOG": 0.9669940492267146, "HUMAN": 1.135052654656425, "HUMIRA": 0.2805578315747513, "INSULATARD": 6.60193873952468, "INSULIN": 0.770462048621078, "INTELENCE": 4.546432581542087, "ISENTRESS": 12.231171269924342, "JANUMET": 0.5326015678218025, "KAFTRIO": 5.8001346411962, "KALETRA": 3.588447613279776, "KALYDECO": 2.9975189812819782, "KEPPRA": 4.106755260062297, "KESIMPTA": 2.745017414611656, "KUVAN": 19.63690358637492, "LACOSAMIDE": 2.1361917251404274, "LAMIVUDINE": 2.324682801906542, "LANTUS": 1.4691501274601655, "LATUDA": 1.171057653375401, "LEMTRADA": 1.3134707660289913, "LEVEMIR": 6.707283555729031, "LEVETIRACETAM": 4.061530013123205, "LEVOFLOXACIN": 0.6058131150044657, "LYRICA": 0.7858734827680232, "MAVENCLAD": 2.48643431592856, "METHOTREXATE": 0.4425272552960779, "MIXTARD": 4.915194563394945, "MMRVAXPRO": 0.8206114285141661, "MODERNA": 0.30423223851481, "NORVIR": 7.254318368077092, "NOVORAPID": 1.3029962963675177, "NPLATE": 0.5130049382156274, "OLANZAPINE": 0.8094886097040472, "OMALIZUMAB": 0.523937566358973, "ORGALUTRAN": 23.42208079717694, "OVITRELLE": 9.620444076127043, "PEGASYS": 2.114093662417026, "PEGINTERFERON": 0.5213212201550372, "PEGINTRON": 2.320057112257917, "PLEGRIDY": 2.4806738283027343, "PRIVIGEN": 0.5952917978248724, "PUREGON": 271.38723846364684, "REBETOL": 1.403725837608477, "RELVAR": 0.99699897755296, "REMICADE": 2.574659936184966, "REYATAZ": 5.654078537973878, "RIBAVIRIN": 0.9010685917800818, "RINVOQ": 0.4305016851106581, "ROACTEMRA": 1.3887359640291603, "SAXENDA": 2.41651665995451, "SIMPONI": 1.1545658699660244, "SKYRIZI": 2.653979182249274, "SOLIRIS": 1.4100904796679885, "SOVALDI": 1.315793410226482, "SPIKEVAX": 0.3329010114284455, "SPINRAZA": 0.7180195639072436, "SPRYCEL": 0.4724788303528249, "STELARA": 3.787954466669033, "SUBOXONE": 13.990258219744732, "TAMIFLU": 1.1735536197312166, "TASIGNA": 0.7962406398272855, "THYROID": 227.04082780582536, "TOZINAMERAN": 1.9270765341861336, "TRACLEER": 0.3826854473570361, "TREMFYA": 2.440747150236648, "TRIUMEQ": 2.1855466614040524, "TRUVADA": 0.3194019239528489, "VAXZEVRIA": 0.2557754971087933, "VICTOZA": 1.051297896130165, "VIMPAT": 1.7393219741442492, "VIREAD": 1.907782076994284, "XELJANZ": 0.2394307031790487, "XOLAIR": 4.235924985411844, "ZYPREXA": 0.910555702870938, "null": 1.307498147345878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/760.json
index 233b50d0548..8a3e614ab2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/760.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/760.json
@@ -1 +1 @@
-{"COMIRNATY": 4.6386364769013095}
\ No newline at end of file
+{"ALEMTUZUMAB": 24.21636794632178, "COMIRNATY": 0.2185936702351083, "GARDASIL": 4.171913179417255, "LEMTRADA": 314.2635925217569, "PEGASYS": 3.157985364535693, "PEGINTRON": 7.516104243376881, "null": 0.7000642698685706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7600.json
index 04f5c42de15..c7c6acb27ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7600.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7600.json
@@ -1 +1 @@
-{"DARBEPOETIN": 17149.396838288594}
\ No newline at end of file
+{"COMIRNATY": 0.5125431406651689, "null": 0.4205070839252257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7601.json
index f2b9046f09b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7601.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7601.json
@@ -1 +1 @@
-{"COVID19": 1.2512065922087685, "KEPPRA": 5.562104261848378, "TOZINAMERAN": 1.7129720031726716, "XYREM": 44.54866766080696, "null": 1.659342988493014}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7602.json
index e40a90ee7b4..aae4e7734bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7602.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7602.json
@@ -1 +1 @@
-{"CHAMPIX": 4.565114610802602, "CYMBALTA": 6.699704772098174, "TAMIFLU": 11.817397149523682, "VFEND": 19.60036207220623, "null": 1.7867001883272289}
\ No newline at end of file
+{"CYTARABINE": 14.07186529698887, "FASTURTEC": 2326.180366476596, "IBUPROFEN": 7.708713393385037, "LEVOFLOXACIN": 11.066133741586894, "RASBURICASE": 3269.9253194698936, "null": 1.979623423768314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7603.json
index 6526e301b21..4e21f5f4a85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7603.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7603.json
@@ -1 +1 @@
-{"ABACAVIR": 2.150067382438213, "APIXABAN": 14.074399239559474, "BIKTARVY": 10.599539352906818, "CHAMPIX": 3.455257523423543, "CYMBALTA": 1.0343202326814491, "KAFTRIO": 16.42130161293499, "KEPPRA": 1.7663065326843144, "TAMIFLU": 25.045044537462992, "XYREM": 16.091386182075908, "null": 3.0040748816687155}
\ No newline at end of file
+{"GARDASIL": 132.95789170707545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7604.json
index 6e10e9d6929..589e0c98277 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7604.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7604.json
@@ -1 +1 @@
-{"XYREM": 401.28825518090326, "null": 1.2383393565278067}
\ No newline at end of file
+{"ATRIPLA": 0.7427548918860333, "EXFORGE": 10.277324364297993, "FORXIGA": 29.055495541353828, "HUMALOG": 18.042419851927026, "INSULIN": 8.419120590345138, "JANUMET": 7.62194937349781, "JARDIANCE": 5.326441628154891, "TRUVADA": 1.401490849145564, "ZYPREXA": 7.341479726927162, "null": 0.8523684294163395}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7605.json
index e7ef27e1260..0b4191e409a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7605.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7605.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 1.4655986044521423, "CYMBALTA": 2.006422507084177, "FENTANYL": 2.668627871806605, "GARDASIL": 1.8061548184654184, "IBUPROFEN": 3.305553509426986, "KEPPRA": 2.468516350666987, "OLANZAPINE": 2.895345675844349, "ZYPREXA": 4.107898254638778, "null": 2.992394011236041}
\ No newline at end of file
+{"AMIKACIN": 70.77640694401363, "CARFILZOMIB": 123.6405543500362, "CICLOSPORIN": 33.368492104861275, "KYPROLIS": 70.73904893702823, "SOLIRIS": 10.13724450905645, "null": 0.7961061421607786}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7606.json
index 630edc124f2..a1eaa2e3d92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7606.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7606.json
@@ -1 +1 @@
-{"BENRALIZUMAB": 55.74648773929575, "CARIPRAZINE": 193.9394958766189, "FYCOMPA": 33.280715340706934, "KEPPRA": 1.9498426182276063, "LANTUS": 1.1762382900078152, "OLANZAPINE": 3.910898243416053, "PEGASYS": 1.2486232993264443, "TOZINAMERAN": 1.293395875054436, "null": 1.346139359663053}
\ No newline at end of file
+{"BUSULFAN": 15.393302402901178, "CICLOSPORIN": 10.970538559534496, "COMIRNATY": 0.4340163858167145, "METHOTREXATE": 55.09763713330798, "SOLIRIS": 9.021246785125504, "SPIKEVAX": 0.3892289915382543, "null": 0.5140957850875935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7607.json
index efc954ac1c1..583196c8637 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7607.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7607.json
@@ -1 +1 @@
-{"ABILIFY": 1.1551467138966265, "APIDRA": 1.8489673978023653, "BRINTELLIX": 2.2588160581806127, "DULOXETINE": 4.876072645790343, "HUMALOG": 1.399089057045488, "IBUPROFEN": 1.3995377742962358, "INLYTA": 2.5229841517033065, "INVEGA": 22.562687853543807, "KEPPRA": 2.4203762340102357, "LANTUS": 3.863098570380712, "OLANZAPINE": 2.8677380398758623, "OPSUMIT": 2.122619446410792, "PEGASYS": 1.0910524242513306, "RINVOQ": 2.085762982981905, "SHINGRIX": 1.024285113954468, "SPIKEVAX": 1.1905886048966492, "SUTENT": 2.2431251981517475, "VAXZEVRIA": 1.0771546599668245, "VIMPAT": 4.189586734818063, "ZYPREXA": 2.448737819521622, "null": 1.3111058198769336}
\ No newline at end of file
+{"PRIVIGEN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7608.json
index a420007509f..4e72fdbff40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7608.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7608.json
@@ -1 +1 @@
-{"null": 1.2903539949423084}
\ No newline at end of file
+{"COMBIVIR": 14.905457190049656, "IBUPROFEN": 10.278007081658211, "KEPPRA": 8.782036507281104, "null": 4.562332481900437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7609.json
index d34ae0f3780..7891d5b06f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7609.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7609.json
@@ -1 +1 @@
-{"FIRDAPSE": 56.72582272075472, "GEFITINIB": 241.04846799687147, "HYCAMTIN": 105.22367541660442, "IRESSA": 17.97279345992964, "LANTUS": 1.7635242309674275, "STELARA": 3.541532418394346, "TAGRISSO": 21.49811021775693, "TOPOTECAN": 69.52729451348233, "TRELEGY": 10.906994696250909}
\ No newline at end of file
+{"KEPPRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/761.json
index 112128583be..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/761.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/761.json
@@ -1 +1 @@
-{"COMIRNATY": 4.298638432552899}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7610.json
index e0942f72557..94519f81d9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7610.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7610.json
@@ -1 +1 @@
-{"null": 1.1422885138152594}
\ No newline at end of file
+{"ARAVA": 2.006933672393702, "CLOPIDOGREL": 3.550493551262321, "COMIRNATY": 0.1220075379460561, "ELIQUIS": 4.3992386061621485, "PLAVIX": 7.309600669819747, "TORISEL": 34.65440871462857, "null": 1.189274499372653}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7611.json
index 6ceb0039616..94d04fa443a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7611.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7611.json
@@ -1 +1 @@
-{"FIRDAPSE": 763.5603741761499}
\ No newline at end of file
+{"ASENAPINE": 2486.398161409357, "COMBIVIR": 171.16376157047154, "null": 0.3927857668761199}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7612.json
index db1a4ddfc7f..c648df438ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7612.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7612.json
@@ -1 +1 @@
-{"COMIRNATY": 4.125506436121609, "GARDASIL": 8.297698284434189, "SPIKEVAX": 1.5311992972277324, "TELMISARTAN": 52.36215712988933, "TOZINAMERAN": 3.89974871465814, "VAXZEVRIA": 1.3293028556267652}
\ No newline at end of file
+{"COMIRNATY": 0.9164647503272676, "SPIKEVAX": 1.0733888253779988, "null": 0.9222379949425142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7613.json
index 7e855ac5766..c0ffc09c123 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7613.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7613.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 5.180718896981786, "CICLOSPORIN": 6.89033277485059, "CIMZIA": 3.0175842901332124, "CYTARABINE": 3.360853853354893, "DEXMEDETOMIDINE": 76.56535589985788, "ENFUVIRTIDE": 210.3907542436804, "GARDASIL": 3.3728275618111363, "HUMALOG": 1.3915631100817776, "ISENTRESS": 51.737514199448384, "KALETRA": 7.863935946196288, "KEPPRA": 17.54548811429398, "LAMIVUDINE": 14.663332322560398, "LEVETIRACETAM": 8.806245491809387, "MISOPROSTOL": 279.07197100062405, "OLANZAPINE": 3.4459214675349013, "SUBOXONE": 8.649421186201847, "null": 1.7944074257943416}
\ No newline at end of file
+{"null": 2.091031042875978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7614.json
index 0489bdf80cb..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7614.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7614.json
@@ -1 +1 @@
-{"AFINITOR": 3.5317128497867434, "CLOPIDOGREL": 16.24375573160993, "EFIENT": 46.33871289750287, "ELIQUIS": 12.762960317976765, "KEYTRUDA": 2.941486796233526, "LIXIANA": 22.434968652812653, "NEXAVAR": 5.025707128924461, "PLAVIX": 11.541507891939714, "null": 1.111847028387986}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7615.json
index babb5e63abc..b4e8720d0d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7615.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7615.json
@@ -1 +1 @@
-{"AFINITOR": 1.9894610100733607, "AIMOVIG": 2.363202196734796, "APIXABAN": 4.9860885399475805, "AVASTIN": 3.1253407510019136, "BEVACIZUMAB": 5.27996869781104, "BRAFTOVI": 4.056177116693562, "BYETTA": 2.865651068245033, "CELLCEPT": 3.902657034682522, "CIMZIA": 5.139344961903111, "CYTARABINE": 3.0910296837717315, "ENTYVIO": 6.424791651399873, "EXJADE": 1.6581484881241295, "FASLODEX": 2.094098128506233, "HUMIRA": 3.6270668390388057, "IBRANCE": 1.3691766047422216, "IRINOTECAN": 8.47455593627557, "JANUMET": 4.288615975899599, "KEYTRUDA": 1.689449927089567, "LONSURF": 13.558433677410653, "LYRICA": 2.5140323324628544, "OPSUMIT": 1.6858379841194313, "RITUXIMAB": 2.8814229693865765, "ROTATEQ": 3.438239630486306, "RUBRACA": 27.70613270006536, "SAXENDA": 2.6217734919539297, "STELARA": 7.414550419634993, "TRULICITY": 4.960041638552545, "VICTOZA": 2.7853069617028905, "null": 1.4475730612339992}
\ No newline at end of file
+{"METHOTREXATE": 16.757383097886745, "null": 4.935728453656419}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7616.json
index 0dba3808403..3567e569364 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7616.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7616.json
@@ -1 +1 @@
-{"ALIMTA": 13.07884455767921, "AVASTIN": 44.311739542033294, "BEVACIZUMAB": 11.586536902182903, "CABOMETYX": 18.60630996275087, "KEYTRUDA": 20.730919977985277, "LENVIMA": 26.649858926258048, "ROACTEMRA": 7.818934608564471, "STELARA": 4.4831553560990285, "STIVARGA": 13.151896442518924, "SUTENT": 2.0281414308822}
\ No newline at end of file
+{"null": 1.1414720922686423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7617.json
index 78a9c3fc575..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7617.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7617.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 47.65729174312905, "STELARA": 19.978112595099883}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7618.json
index 96e14bd1110..96d01983cd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7618.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7618.json
@@ -1 +1 @@
-{"STELARA": 42.25839490229045}
\ No newline at end of file
+{"null": 2.1811474582026085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7619.json
index bb5e1d4d67e..b7fa641c933 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7619.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7619.json
@@ -1 +1 @@
-{"STELARA": 5.868201334005183, "null": 3.057660323197817}
\ No newline at end of file
+{"null": 2.914643786540521}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/762.json
index fd5818664b5..687919f0f42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/762.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/762.json
@@ -1 +1 @@
-{"COVID19": 1.0850571263479405, "IPILIMUMAB": 63.58495963716963, "KEYTRUDA": 32.68431358077445, "TOZINAMERAN": 3.0927091769708768}
\ No newline at end of file
+{"IBUPROFEN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7620.json
index c9e5e3559a9..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7620.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7620.json
@@ -1 +1 @@
-{"AFINITOR": 113.71806631872823}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7621.json
index 22514f5ccc8..101cdcc2f59 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7621.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7621.json
@@ -1 +1 @@
-{"null": 1.070559733320756}
\ No newline at end of file
+{"COMIRNATY": 1.2161514243822622, "SPIKEVAX": 0.6682693612743612, "null": 0.5788047571616325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7622.json
index f04b64d9a39..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7622.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7622.json
@@ -1 +1 @@
-{"null": 1.8420981004812824}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7623.json
index fdffa6dd24c..7cc425e585b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7623.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7623.json
@@ -1 +1 @@
-{"null": 1.7203581838430817}
\ No newline at end of file
+{"null": 0.5519605119142673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7624.json
index 71e5619b366..c11fb35860e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7624.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7624.json
@@ -1 +1 @@
-{"ANAKINRA": 72.09996219437022, "GARDASIL": 96.01306276343556}
\ No newline at end of file
+{"ALEMTUZUMAB": 261.446233281346, "CICLOSPORIN": 26.40637814322201}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7625.json
index 1dc2ca72ef7..dd161db73cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7625.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7625.json
@@ -1 +1 @@
-{"GARDASIL": 294.7495062299504}
\ No newline at end of file
+{"null": 1.5608023183884372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7626.json
index b6068b8e5d5..9fc553635ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7626.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7626.json
@@ -1 +1 @@
-{"OMALIZUMAB": 158.71231093760247}
\ No newline at end of file
+{"CELLCEPT": 62.10688503470335, "null": 1.2190407829362462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7627.json
index 8e8708818c5..8ce6a128ce5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7627.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7627.json
@@ -1 +1 @@
-{"null": 1.8095346180134173}
\ No newline at end of file
+{"COMIRNATY": 0.8230160526482495, "null": 0.5244050423572348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7628.json
index 0d35801b2f2..ccbe8310f34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7628.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7628.json
@@ -1 +1 @@
-{"CAELYX": 191.984106825042, "CICLOSPORIN": 138.06063727027387, "MYCOPHENOLATE": 116.2992879854938}
\ No newline at end of file
+{"null": 3.612151837161976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7629.json
index 28ebb55d38e..37f92659366 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7629.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7629.json
@@ -1 +1 @@
-{"AVAMYS": 6.813494220316039, "BENLYSTA": 2.040137068363641, "BUDESONIDE": 11.887005014778293, "BUPRENORPHINE": 1.4825684728542412, "CAPECITABINE": 1.3555118691515775, "COMIRNATY": 1.0582894845131752, "COSENTYX": 1.164865456035305, "COVID19": 1.184218594016358, "DARZALEX": 2.0162897187700253, "EXFORGE": 1.3976926200913014, "FASENRA": 1.4527497772964133, "FLUTICASONE": 26.80200054473009, "GREPID": 37.0227655022944, "MEPOLIZUMAB": 2.7960590243849404, "NUCALA": 16.031872127516685, "OCRELIZUMAB": 6.554693245858747, "OMALIZUMAB": 2.276062165974288, "OZEMPIC": 11.60759525398657, "RELVAR": 2.589535172552131, "REVATIO": 1.2302624250052925, "SUBOXONE": 3.5518551041099613, "SYNAGIS": 1.8408666052120168, "TOZINAMERAN": 2.4176557320064656, "XOLAIR": 4.156687875883475, "null": 1.390341753411061}
\ No newline at end of file
+{"HARVONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/763.json
index 1ae1c28097a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/763.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/763.json
@@ -1 +1 @@
-{"INFLIXIMAB": 43.81774354727842, "INLYTA": 14.635524403602489, "IPILIMUMAB": 325.5770944991305, "KEYTRUDA": 37.19573488581798, "NIVOLUMAB": 277.12504022806064, "OPDIVO": 95.6025489184596, "PEMBROLIZUMAB": 49.98372814426921, "YERVOY": 250.55159493718256}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7630.json
index db4e6aa252f..01159689b8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7630.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7630.json
@@ -1 +1 @@
-{"AIMOVIG": 2.2724801373612182, "APIXABAN": 2.275425030855017, "BENRALIZUMAB": 44.38388873104851, "CHAMPIX": 2.2131542156405373, "CYMBALTA": 3.43730149302737, "DUAKLIR": 360.10651294337424, "FENTANYL": 5.776372096461027, "HUMALOG": 7.89045088823018, "MEPOLIZUMAB": 8.745649561522661, "OLANZAPINE": 2.157603759288647, "PREGABALIN": 28.22558461408178, "SOMATROPIN": 88.88864192627597, "TRELEGY": 4.02587100078112, "XYREM": 19.3089756108348, "ZOSTAVAX": 3.690172928231879, "null": 1.8135447589668447}
\ No newline at end of file
+{"ATRIPLA": 0.8028317787349736, "COMIRNATY": 0.2628256290498926, "CYMBALTA": 1.766945662355753, "FORXIGA": 3.533588421433233, "INCRUSE": 12.138668609296312, "IRON": 19.86753372622351, "JARDIANCE": 3.5368475804996047, "KEPPRA": 0.9411267888719396, "LANTUS": 0.6357995007688295, "NUCALA": 1.7894173315572202, "PEGASYS": 0.6893731416379125, "SPIKEVAX": 0.1879668334076355, "SUTENT": 0.7309032462805339, "TOVIAZ": 16.291095437403083, "TOZINAMERAN": 0.2401086220832816, "TRELEGY": 5.215362605872128, "VAXZEVRIA": 0.1565335436646166, "VIAGRA": 2.5469118237308632, "ZYPREXA": 2.2019781419053555, "null": 2.3804240711935845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7631.json
index 105fb236bc9..72065cd2ac7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7631.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7631.json
@@ -1 +1 @@
-{"null": 4.864214213955248}
\ No newline at end of file
+{"IBUPROFEN": 46.92675426571587, "JARDIANCE": 5.962642791561585, "null": 1.9585478273469583}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7632.json
index 55327fc9c03..c9f7034cfe3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7632.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7632.json
@@ -1 +1 @@
-{"ABILIFY": 8.345624915886523, "ARIPIPRAZOLE": 48.88008588345872, "BUPRENORPHINE": 15.279515369689966, "CYMBALTA": 3.031544647647328, "SUBOXONE": 7.535644460978017, "null": 1.811490290577275}
\ No newline at end of file
+{"ARIPIPRAZOLE": 1.175130896047897, "ATRIPLA": 0.1918668099392569, "AUBAGIO": 4.439556515164928, "AZILECT": 21.221128594536346, "BETMIGA": 16.102872177207068, "BRINTELLIX": 1.2397004545568708, "CHAMPIX": 0.6850994577878532, "COMIRNATY": 0.507084208750477, "CYMBALTA": 0.9757757182172272, "ELIQUIS": 0.6083287048416217, "ELMIRON": 80.6509196419714, "EXFORGE": 5.286877279446814, "FAMPYRA": 4.092744438111777, "FASLODEX": 2.025270188398489, "FORSTEO": 9.363612741052922, "FORXIGA": 8.928704682433906, "GARDASIL": 0.7912719267799178, "HUMALOG": 0.9812668954965412, "IBRANCE": 0.5559594192080077, "IBUPROFEN": 0.9284843199745516, "JANUVIA": 0.79311318244795, "JARDIANCE": 12.699961564650042, "KEPPRA": 0.4301346976826955, "LANTUS": 0.4317808371035735, "MICARDIS": 1.9448994651345972, "NOT": 3.395840337597743, "OLANZAPINE": 0.9625608101982198, "OXYBUTYNIN": 13.688573523647792, "PEGASYS": 0.2484639795541233, "PEGINTRON": 0.5896949183064586, "SPIKEVAX": 0.5466078862159488, "STRIBILD": 0.7029751334541129, "TOVIAZ": 23.460789938807768, "TOZINAMERAN": 0.6973779285845566, "TRUVADA": 0.258333563050533, "VAXZEVRIA": 0.5458863786148398, "XELJANZ": 1.4681503084406708, "XTANDI": 1.8861844114186408, "ZOSTAVAX": 1.2084198454150037, "ZYPREXA": 0.6325461860439369, "null": 1.4237666895309082}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7633.json
index 0b1bd1dcaac..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7633.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7633.json
@@ -1 +1 @@
-{"ABACAVIR": 1.441650356392475, "ABILIFY": 15.426590235610645, "ANTIBIOTICS": 29.35255761224113, "ARIPIPRAZOLE": 9.2047101143297, "AVAMYS": 3.2169048698569287, "BRINTELLIX": 4.335618633864014, "CHAMPIX": 14.43004080484692, "CYMBALTA": 2.907042681504529, "FENTANYL": 1.9854790462605247, "GARDASIL": 4.90207343166977, "KEPPRA": 3.247288359744438, "LATUDA": 6.315277835281716, "LEVETIRACETAM": 2.878733973638248, "LYRICA": 2.2284792188845395, "OLANZAPINE": 5.602915092644413, "ZYPREXA": 4.470849860454311, "null": 2.946083142596406}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7634.json
index 3a33965bc1c..2cdfb920e01 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7634.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7634.json
@@ -1 +1 @@
-{"ABILIFY": 47.904674034745575, "null": 1.388232084887758}
\ No newline at end of file
+{"COMIRNATY": 0.6007924399648058, "ELIQUIS": 12.25072079493657, "VAXZEVRIA": 0.9021283894519424, "null": 0.4936011879671621}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7635.json
index 9c3fa53da82..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7635.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7635.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 5.157767562418332, "BELIMUMAB": 85.62767969823344, "BENLYSTA": 28.13200456572907, "MEPOLIZUMAB": 15.03837522639011, "NUCALA": 16.87482700352584, "PLAVIX": 5.501297041371289, "SHINGRIX": 2.6676622469391456, "null": 4.612538747649669}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7636.json
index d67a8cae467..8381c19e80a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7636.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7636.json
@@ -1 +1 @@
-{"null": 1.070213856071489}
\ No newline at end of file
+{"null": 1.6942404670543447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7637.json
index cfe655be858..7ca13177a94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7637.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7637.json
@@ -1 +1 @@
-{"ARAVA": 8.016844953796777, "OPTIMARK": 19.112653642371285}
\ No newline at end of file
+{"COMIRNATY": 0.6575409140206875, "SPIKEVAX": 0.429211174277969, "TOZINAMERAN": 0.9228264763698728, "null": 1.0128834451469466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7638.json
index a13ec2cf315..6c2d5a81856 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7638.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7638.json
@@ -1 +1 @@
-{"ELIQUIS": 7.846142889654954, "null": 1.389702900708209}
\ No newline at end of file
+{"COMIRNATY": 1.2503734290954442, "SPIKEVAX": 1.8911606157957963, "null": 1.0302240819951054}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7639.json
index 80106c1d006..0ec15c855c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7639.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7639.json
@@ -1 +1 @@
-{"CICLOSPORIN": 8.468403573382417, "ROACTEMRA": 18.621910898572697}
\ No newline at end of file
+{"ADALIMUMAB": 0.1649843858646996, "AIMOVIG": 7.414747153806142, "ARAVA": 0.1209782697001145, "AUBAGIO": 0.7237577406290943, "AVAMYS": 3.038624591578826, "BIKTARVY": 2.039092749231868, "BRINTELLIX": 2.779059025093731, "BUDESONIDE": 16.57526114968571, "BYDUREON": 0.859624820885037, "CHAMPIX": 1.8547917960823737, "CIMZIA": 0.2675530893288685, "CIRCADIN": 21.07027534721172, "COMIRNATY": 0.8203494031227297, "COSENTYX": 0.7982527459198886, "CPAP": 160.24441423630603, "CYMBALTA": 0.7074752442847742, "DEXAMETHASONE": 0.8757212153823026, "EFAVIRENZ": 3.973115202063137, "ELIQUIS": 0.2195160578691742, "ENBREL": 0.652583602870189, "ENTRESTO": 0.5815342962798764, "ESBRIET": 1.7672587935125037, "FASENRA": 4.012198023083519, "FLUTICASONE": 5.901703726046209, "HUMIRA": 3.557310666457586, "IBRANCE": 0.5656805969172378, "JANUVIA": 1.2447859237494174, "KAFTRIO": 9.649663743038277, "KEPPRA": 0.4587810215548776, "LATUDA": 2.0868334972548768, "LEVETIRACETAM": 0.9369448014443644, "LYRICA": 1.3126804057090102, "MELATONIN": 46.08638523006889, "MEPOLIZUMAB": 12.030631464728597, "METHOTREXATE": 0.7531323877546059, "MMRVAXPRO": 1.8565523456272812, "NUCALA": 6.167714308246097, "OLANZAPINE": 1.1579158949264827, "OMALIZUMAB": 25.710354400427477, "PANTOPRAZOLE": 1.5890070296020875, "PEGINTRON": 0.5620944377529419, "PREGABALIN": 10.016828619837776, "RINVOQ": 3.485751518855452, "SHINGRIX": 0.9441078390934976, "SLENYTO": 108.16237748116951, "SPIKEVAX": 0.5427970286042413, "SUTENT": 0.2082007778233293, "TAMIFLU": 0.989268816639718, "TOVIAZ": 5.353819996751486, "TOZINAMERAN": 0.8422438599821601, "TRELEGY": 1.3613273201107037, "VAXZEVRIA": 0.296724311104346, "XELJANZ": 2.046663199343698, "XOLAIR": 3.682727916880797, "XTANDI": 0.612592528778856, "null": 1.071409458772756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/764.json
index bb2c5b74fb5..601c0c8268b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/764.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/764.json
@@ -1 +1 @@
-{"OPDIVO": 78.15567788188058}
\ No newline at end of file
+{"null": 1.4245068139663926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7640.json
index e49a298b39f..4963ee55582 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7640.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7640.json
@@ -1 +1 @@
-{"AIMOVIG": 115.21539016610366, "JANUVIA": 23.419770355256897}
\ No newline at end of file
+{"ABATACEPT": 0.1478265620328292, "ABILIFY": 0.4843122365840444, "ADALIMUMAB": 0.8616890010318597, "ADCIRCA": 0.6456634038077055, "ADEMPAS": 0.9006221743736075, "AERIUS": 0.6400125025837556, "AFINITOR": 0.0496826497508289, "AIMOVIG": 28.99692775504345, "AJOVY": 6.688695826128155, "ALEMTUZUMAB": 0.3526148269045061, "AMINOSALICYLIC": 0.5158965513509632, "ANAKINRA": 0.2634976036887986, "APIXABAN": 2.2235234755948925, "APREMILAST": 2.620634789629685, "ARANESP": 0.1028553393197424, "ARAVA": 0.4621382243456198, "ATRIPLA": 0.0262919928519831, "AUBAGIO": 1.023979182690404, "AVAMYS": 1.4250351670855568, "AVANDIA": 0.0462728871969689, "AZATHIOPRINE": 0.6571265637064746, "BELIMUMAB": 1.2809832081449355, "BENLYSTA": 1.892005078836748, "BETAFERON": 0.3540452440674304, "BETMIGA": 0.7896060156704623, "BIKTARVY": 0.5274689775932305, "BOSULIF": 0.2519330574897861, "BOTULINUM": 28.448258653596724, "BRAFTOVI": 0.1850328270106985, "BRINTELLIX": 1.0923170069651609, "BRIVIACT": 0.4576165080894401, 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1.1169347886857948, "EVISTA": 0.4616629907349924, "EVRA": 1.5986903268627877, "EXJADE": 0.0845870349486245, "FAMPYRA": 0.4842026212174694, "FASENRA": 0.7954332070533098, "FASLODEX": 0.3418298739576129, "FENTANYL": 0.1524287637551756, "FIRDAPSE": 1.06289705436245, "FLEBOGAMMA": 0.757958169946434, "FLUCELVAX": 1.2036063724134003, "FORSTEO": 0.3536228439242486, "FORXIGA": 0.2617747262683088, "GARDASIL": 2.355015301968417, "GILENYA": 1.062638633088275, "HARVONI": 0.2897008568250133, "HIZENTRA": 2.597212908710439, "HUMALOG": 0.2261577613982714, "HUMAN": 0.5162397659551989, "HUMIRA": 1.1771255672993772, "HYDROCORTISONE": 1.7228271629083298, "HYQVIA": 1.3596217755945244, "IBRANCE": 0.2994363699832616, "IBUPROFEN": 0.5729465810278279, "IMATINIB": 0.9764077952269968, "INTRONA": 0.6072971141584603, "IXIARO": 3.240425740413696, "JANSSEN": 1.5929218019562628, "JANUMET": 0.2269898806363244, "JARDIANCE": 0.0620294004830074, "KAFTRIO": 0.8478887535618614, "KALYDECO": 1.091979194276287, "KEPPRA": 0.4710536568398391, "KESIMPTA": 1.058480573121137, "LACOSAMIDE": 0.2446537660379095, "LANTUS": 0.2097180614341333, "LATUDA": 0.5303419080289433, "LEMTRADA": 0.311840858316346, "LEVETIRACETAM": 0.2530523329997333, "LEVOFLOXACIN": 0.1739843326692925, "LYRICA": 1.3130266630327438, "MAVENCLAD": 0.4815502233809889, "MEKINIST": 0.1533752981165061, "MELATONIN": 0.6633034136535133, "MENVEO": 0.9695475579090462, "MEPOLIZUMAB": 0.2078689776783212, "METHOTREXATE": 0.8091873850597219, "MICARDIS": 0.1406861238760313, "MMRVAXPRO": 0.1362765274625461, "MODERNA": 0.773575329753429, "NIMENRIX": 0.4008081641777241, "NOT": 0.2456400743768443, "NUCALA": 0.3697131803821131, "OCRELIZUMAB": 5.484802571288236, "OMALIZUMAB": 1.265861150883421, "OPSUMIT": 0.3508069914799153, "OXYBUTYNIN": 0.7448959332698466, "PEGASYS": 0.6374515738168667, "PEGINTRON": 0.719136829572953, "PLAVIX": 0.1511685413650487, "PLEGRIDY": 1.031730955691425, "PREGABALIN": 0.6245052581861968, "PRIVIGEN": 1.4015911705464352, "PROPRANOLOL": 1.680424726593756, "RELVAR": 0.7299115147359133, "REMICADE": 0.97062807297848, "REVATIO": 0.4052063545273914, "RINVOQ": 0.3978088970189478, "RITUXIMAB": 0.1550192434169941, "ROACTEMRA": 0.451722042308199, "RUCONEST": 1.381741240940003, "RYBELSUS": 0.4543835800486592, "SAXENDA": 1.3513557612238982, "SHINGRIX": 0.355297904762068, "SIFROL": 0.778052586870577, "SILDENAFIL": 0.4391122744800239, "SIMPONI": 0.5248806681151508, "SKYRIZI": 0.6972929345731255, "SOLIRIS": 0.5158000023690111, "SOVALDI": 0.2779590848274056, "SPIKEVAX": 1.2653443782734606, "SPINRAZA": 0.6993241697266924, "SPRYCEL": 0.5466559299589296, "STELARA": 1.8983047328919176, "STIVARGA": 0.0855239393494505, "SUBOXONE": 1.0051236646027624, "SUTENT": 0.12542164047434, "TAMIFLU": 0.1716058241929316, "TASIGNA": 0.3697109683514073, "TOVIAZ": 0.1699675862626123, "TOZINAMERAN": 3.114680014633353, "TRACLEER": 0.229719130049959, "TRELEGY": 0.1719280263157757, "TREMFYA": 0.5643400766283834, "TRULICITY": 0.2950256650661712, "TRUVADA": 0.0296108481042505, "TWINRIX": 0.7068561257587552, "VAXZEVRIA": 2.7533005778793096, "VIAGRA": 0.4197984257374148, "VICTOZA": 0.2135642674409485, "VIMPAT": 0.4322905105091861, "VOTRIENT": 0.1618121069740164, "XELJANZ": 0.7149835663294638, "XOLAIR": 1.1839044256186813, "XYREM": 2.75245547697651, "ZONEGRAN": 4.0665620084698375, "ZONISAMIDE": 4.844660135959851, "ZOSTAVAX": 0.5677732677449111, "ZYPREXA": 0.1214747584943658, "null": 0.4573081556954237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7641.json
index d4c0a13a4a9..0e648fd26b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7641.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7641.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 10.947501307617369, "null": 2.2961430603263304}
\ No newline at end of file
+{"AIMOVIG": 10.559804359210808, "AZATHIOPRINE": 2.556878498033143, "BELIMUMAB": 18.825022305191485, "BOTULINUM": 18.840319889918277, "CICLOSPORIN": 1.490926272003258, "COMIRNATY": 2.5027434453206827, "CYMBALTA": 0.4207185074427294, "GARDASIL": 3.4332702480461625, "MODERNA": 1.3763084630807292, "OCRELIZUMAB": 3.3764880255750924, "SPIKEVAX": 1.277430243342866, "STELARA": 1.096604349232974, "TOZINAMERAN": 3.997243033140745, "VAXZEVRIA": 2.51151248079248, "null": 0.3178073665966661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7642.json
index 7c4e1aa3b7e..2555a24fd5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7642.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7642.json
@@ -1 +1 @@
-{"MEKINIST": 58.41541493545706, "PAZOPANIB": 266.8290850373411, "SUTENT": 1.979922508950664, "VOTRIENT": 317.1814984074679}
\ No newline at end of file
+{"AIMOVIG": 15.319793756529048, "COMIRNATY": 0.5339098385272564, "CYMBALTA": 3.623405222915592, "ERENUMAB": 173.33544977004564, "GARDASIL": 9.275656764706726, "SPIKEVAX": 0.406528330615095, "TOZINAMERAN": 1.342273091424148, "VAXZEVRIA": 1.3401075474127744, "ZOSTAVAX": 6.889920264202496, "null": 0.8618510522734774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7643.json
index 7d1a602b494..f53ce6703b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7643.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7643.json
@@ -1 +1 @@
-{"ARAVA": 5.49261517478714, "COMIRNATY": 2.100855142256637, "METHOTREXATE": 12.658709017066622}
\ No newline at end of file
+{"null": 0.6323398372150759}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7644.json
index cd36b12ceb6..78346f9034a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7644.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7644.json
@@ -1 +1 @@
-{"COTELLIC": 156.49582911159865, "ESBRIET": 35.13612112450818, "OLYSIO": 83.46544440553645}
\ No newline at end of file
+{"COMIRNATY": 0.762961955957425, "SPIKEVAX": 0.9727304786324926, "TOZINAMERAN": 3.788329273915224, "VAXZEVRIA": 2.441887065097841, "null": 0.7318950960424765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7645.json
index efd09ae1e2a..3221569b69c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7645.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7645.json
@@ -1 +1 @@
-{"LATUDA": 22.695998013031364, "ZYPREXA": 7.375252268434184, "null": 2.309302617868032}
\ No newline at end of file
+{"ABILIFY": 10.850711345683438, "ROTATEQ": 216.33844959140868, "null": 1.5321672398043984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7646.json
index 6a6b32a7ee4..de2e7e8b34d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7646.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7646.json
@@ -1 +1 @@
-{"OLANZAPINE": 79.8906018459257, "null": 1.967405165801844}
\ No newline at end of file
+{"null": 3.3557558313726283}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7647.json
index 709d1aa9fed..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7647.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7647.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4711961112766736}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7648.json
index 855f06061d5..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7648.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7648.json
@@ -1 +1 @@
-{"null": 1.4041731741611954}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7649.json
index e02fdea263c..a4f46727b2f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7649.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7649.json
@@ -1 +1 @@
-{"ABILIFY": 18.37543113785225, "ARIPIPRAZOLE": 9.34803831619484, "COMIRNATY": 1.1272216520205625, "COSENTYX": 2.216457840070845, "CYMBALTA": 3.0790059857478966, "FENTANYL": 4.019509959146072, "GARDASIL": 15.360080516056057, "OLANZAPINE": 2.7480651906108675, "TWINRIX": 10.998725969201692, "ZYPREXA": 1.668168994538399, "null": 1.0354838981089016}
\ No newline at end of file
+{"COMIRNATY": 2.2329700503312644, "GARDASIL": 4.201598200555135, "SPIKEVAX": 1.0042497756783042, "VAXZEVRIA": 2.2962440539976603, "null": 0.2641016770106456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/765.json
index 0846cd7ac07..ba72de09d54 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/765.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/765.json
@@ -1 +1 @@
-{"ABACAVIR": 2.074002188302761, "ABATACEPT": 23.456468274596308, "ADALIMUMAB": 19.82046646087161, "AIMOVIG": 1.345952530134543, "AMINOSALICYLIC": 1.5936323875179308, "APREMILAST": 17.645462022278814, "APREPITANT": 8.58288867959757, "ARAVA": 4.1218174645105154, "COSENTYX": 1.1567609183448877, "FASENRA": 1.5849637016739204, "FIRDAPSE": 2.866852161161946, "GARDASIL": 9.804258908793251, "INLYTA": 1.2807509569689564, "IPILIMUMAB": 1.4477436805268251, "KEYTRUDA": 1.4856588065610885, "LACOSAMIDE": 1.8724300831733092, "LEMTRADA": 2.389570673242441, "MYCOPHENOLATE": 4.464571586242477, "OMALIZUMAB": 1.3068082974646325, "PEGINTRON": 1.276740181758285, "PROLIA": 9.30614159252814, "RINVOQ": 2.607852776472039, "SHINGRIX": 1.2447035343738089, "TOZINAMERAN": 2.0335366139858992, "TWINRIX": 2.7644421847759544, "XELJANZ": 1.8321776105448384, "XOLAIR": 1.1166542728062885, "ZOSTAVAX": 2.838036789335068}
\ No newline at end of file
+{"null": 4.623753573173521}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7650.json
index 6e93f4133a5..399a070e4c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7650.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7650.json
@@ -1 +1 @@
-{"null": 1.1646108727749316}
\ No newline at end of file
+{"null": 1.2556818847280442}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7651.json
index 0e79520fca1..19aa55efab3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7651.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7651.json
@@ -1 +1 @@
-{"BRINTELLIX": 3.994705355378289, "BUPRENORPHINE": 35.9118997521194, "CHAMPIX": 9.140703014946228, "CYMBALTA": 2.928567944773277, "KEPPRA": 1.8449250770206849, "LATUDA": 5.197930357832098, "LYRICA": 3.3853701653873003, "OLANZAPINE": 5.7574073115956, "TAMIFLU": 7.370116070983693, "XYREM": 52.219381996692576, "ZYPREXA": 2.535021429605959, "null": 2.916047669671962}
\ No newline at end of file
+{"null": 0.64382273080307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7652.json
index 8f4f540f9d1..fc6579d6396 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7652.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7652.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.2866733730422888, "ABILIFY": 1.9069744961496855, "ACE": 2.3274250506578853, "ACIDOPHYLUS": 46.77244108890707, "AERIUS": 4.629284085290047, "AGOMELATINE": 1.4584646628853313, "ALL": 1.1832242071071897, "ANAGRELIDE": 2.740874758088238, "ARIPIPRAZOLE": 1.6001731411980928, "ASENAPINE": 2.202478123483944, "AXURA": 5.9768366257736085, "BENZODIAZEPINE": 1.6676552808478295, "BENZODIAZEPINES": 2.2169361162525343, "BEXSERO": 2.163550754731656, "BEXTRA": 1.4355056808413396, "BRIMONIDINE": 3.783756865054755, "BRINTELLIX": 2.576071450070599, "BRIVARACETAM": 3.6738898939732985, "BRIVIACT": 3.7794468364786327, "BUCCOLAM": 5.271483754993824, "BUPIVACAINE": 1.8176230291992048, "BUPRENORPHINE": 2.2048592885403626, "CANNABIDIOL": 3.6130702012466345, "CARBIDOPA": 2.0868201376493394, "CHAMPIX": 1.832722826115723, "CIRCADIN": 7.877651380703721, "COMTAN": 2.316880614122529, "CYMBALTA": 1.6579925148476102, "DESLORATADINE": 3.3077312639454184, "DIACOMIT": 6.659640569433, "DULOXETINE": 3.277546102649138, "EBIXA": 5.354971726479438, "EDURANT": 1.1528616243333918, "ELLAONE": 1.0062436534296415, "ENALAPRIL": 1.377817776538375, "ENTACAPONE": 1.8994707079033877, "EPIDYOLEX": 8.75558967888187, "EXELON": 3.2077006540019144, "EXVIERA": 1.304512748913062, "FENTANYL": 2.289324305510296, "FLUTICASONE": 1.4815890317160472, "FYCOMPA": 6.647284504299689, "GLIBENCLAMIDE": 1.398686130561524, "GRANISETRON": 5.328507709187519, "HEMANGIOL": 2.54127000041944, "HEXYON": 1.347003250282125, "IBUPROFEN": 2.5205927263707903, "INFANRIX": 2.392150133856682, "INOVELON": 8.28225396259289, "INVEGA": 2.9298820006767348, "KEPPRA": 4.439646969167794, "LACOSAMIDE": 2.954087173204213, "LATUDA": 2.1809391711168744, "LEVETIRACETAM": 2.714435136409663, "LEVODOPA": 2.4987852500368537, "LOXAPINE": 3.003379631822912, "LURASIDONE": 1.3738602903387631, "LYRICA": 4.276325181778902, "LYSODREN": 3.620144475900979, "MELATONIN": 3.938401371397709, "MEMANTINE": 2.310396567725583, "MENVEO": 1.3257006001718172, "MIDAZOLAM": 2.119742858544856, "MIRAPEXIN": 6.10735563055617, "MMRVAXPRO": 3.481136738876428, "NALOXONE": 3.1612197135021844, "NEUPRO": 3.7610233048737256, "NIMENRIX": 2.4824931485470305, "NOT": 1.0470130235109731, "OCALIVA": 1.3422497303669458, "OCRELIZUMAB": 4.509738093834221, "OLANZAPINE": 3.6051522537141913, "OPIOIDS": 2.160562168160004, "OXYBUTYNIN": 1.3988216661139787, "PALIPERIDONE": 1.184179320986124, "PERAMPANEL": 3.51008302730924, "PRAMIPEXOLE": 6.535247268881274, "PREGABALIN": 3.577890070124957, "PREVENAR": 1.7939828593483338, "PROPRANOLOL": 1.486480238069842, "REAGILA": 2.105369344390159, "RISPERIDONE": 2.3903874744104963, "RIVASTIGMINE": 5.116450159824217, "ROTARIX": 2.363075003142224, "ROTATEQ": 1.132854614758531, "SERTRALINE": 5.187009858581808, "SIFROL": 4.6624266050746455, "SLENYTO": 3.3420522460603426, "SODIUM": 3.1921552910163924, "STALEVO": 2.161071015318711, "SUBOXONE": 1.2505806544209734, "SUBSTANCE": 3.336490258118699, "SYCREST": 3.4205957278044186, "TOVIAZ": 1.3936222143393224, "VALDOXAN": 6.722082735964027, "VAXZEVRIA": 1.5817258493635689, "VIGABATRIN": 1.2014856628370616, "VIMPAT": 4.072442606486097, "XTANDI": 1.189473728555432, "XYREM": 4.256591348738217, "YESCARTA": 1.509811651578835, "ZALASTA": 6.366280307194479, "ZONISAMIDE": 3.321232073056642, "ZYPADHERA": 13.286736649537692, "ZYPREXA": 2.9963627612934185, "null": 1.9295926539659405}
\ No newline at end of file
+{"COMIRNATY": 0.40631487621216, "ELIQUIS": 9.850256731934676, "OPSUMIT": 62.02106244639871, "TRACLEER": 43.14966987734736, "null": 0.239377253921359}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7653.json
index b70745d4286..6384ced8628 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7653.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7653.json
@@ -1 +1 @@
-{"ZYPREXA": 13.438557631669282, "null": 5.159839539581868}
\ No newline at end of file
+{"MITOTANE": 28927.234211841896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7654.json
index 762ddbe714c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7654.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7654.json
@@ -1 +1 @@
-{"ABILIFY": 4.072121364993928, "ACTRAPID": 7.838605003762248, "APIDRA": 16.184612484409396, "ARIPIPRAZOLE": 1.096206461107128, "BRINTELLIX": 2.399595913671608, "CYMBALTA": 2.0453293868930724, "HUMALOG": 7.000230499893152, "IBUPROFEN": 4.6808137112386605, "INSULIN": 1.496959462476176, "INVEGA": 21.06219722126083, "KEPPRA": 4.538474149662102, "LANTUS": 3.517566436496857, "LEVEMIR": 2.267081193228252, "LEVETIRACETAM": 2.609389755601128, "LYRICA": 5.673833173102482, "NOVONORM": 32.19721331352718, "OLANZAPINE": 6.3811161769568, "REPAGLINIDE": 44.78243475853676, "SYCREST": 12.741456486049302, "ZYPADHERA": 9.28064573873982, "ZYPREXA": 5.251701376504839, "null": 4.910823340227829}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7655.json
index 68d5b4cae76..4c0646ef5c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7655.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7655.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 83.15261524671358, "OLANZAPINE": 62.15194642266471, "null": 1.2223925931976785}
\ No newline at end of file
+{"null": 2.530447090273517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7656.json
index 568c5259914..fa83e9169b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7656.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7656.json
@@ -1 +1 @@
-{"COMIRNATY": 4.997727888674078, "SPIKEVAX": 2.011614554980645}
\ No newline at end of file
+{"AZACITIDINE": 124.9021968373036, "CLOPIDOGREL": 9.26544635532752, "CYTARABINE": 33.544187395813935, "KYMRIAH": 403.7936048847712, "VENETOCLAX": 273.2854754181052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7657.json
index 5216b0043e1..b6bb8c888b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7657.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7657.json
@@ -1 +1 @@
-{"null": 3.787364818909382}
\ No newline at end of file
+{"CUBICIN": 685.2128261388098, "DAPTOMYCIN": 5070.275694688478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7658.json
index 03ea568281f..97faa1f6507 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7658.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7658.json
@@ -1 +1 @@
-{"ABILIFY": 1.970234113218867, "APIDRA": 1.3237451327031398, "ARIPIPRAZOLE": 1.4973314256005836, "AUBAGIO": 2.2905091293660647, "BENLYSTA": 1.18555802479066, "BOSULIF": 1.2399750524220097, "BRAFTOVI": 1.9517234572824744, "BRIVARACETAM": 2.9433795418342923, "BUMETANIDE": 4.223316646849057, "BUPIVACAINE": 1.495411496962135, "CARBIDOPA": 5.413786438399397, "CHAMPIX": 1.7409339673421256, "COLESEVELAM": 145.40084618508902, "COMTAN": 2.06224996574895, "CYMBALTA": 1.4820749409194065, "DAKLINZA": 2.367067336722572, "DESLORATADINE": 3.6926575066760736, "EBIXA": 4.3768628219594525, "EXELON": 3.3351590841194314, "EXFORGE": 1.6880597878465498, "EYLEA": 1.0382326441044067, "FAMPYRA": 2.40039028875961, "FASENRA": 1.00652758769771, "FIRDAPSE": 3.0044186285394074, "FYCOMPA": 1.2355713557536498, "GARDASIL": 1.4645469823237436, "GLIBENCLAMIDE": 2.7727315351549358, "HUMALOG": 1.7035310492203248, "IBRANCE": 1.2108129681837672, "INFANRIX": 1.0706670161649616, "INLYTA": 1.61408146078662, "INVANZ": 7.385535311030932, "IRINOTECAN": 1.2955441288836262, "KEPPRA": 3.465666319965071, "KESIMPTA": 1.3090656862406769, "LACOSAMIDE": 1.3810300953818733, "LANTUS": 2.1145559751661924, "LATUDA": 2.904407322262264, "LEVETIRACETAM": 1.4733024230360838, "LEVODOPA": 4.789574844356002, "LYRICA": 3.746990753168942, "OLANZAPINE": 2.855620406661849, "OLYSIO": 1.0089916475482883, "OXYBUTYNIN": 1.505637057172924, "PLAVIX": 1.2443877961011067, "PLEGRIDY": 1.1694167790424406, "PREGABALIN": 1.1744095435359578, "PREVENAR": 1.5355495492089095, "RASILEZ": 1.1709791778498733, "RELVAR": 1.107533708368828, "RILUTEK": 8.068271285287935, "SIFROL": 1.500748577226435, "STALEVO": 4.318665600082211, "SUTENT": 1.0608605588847295, "TAMIFLU": 2.358247846560329, "TELMISARTAN": 1.3717601853624326, "TOVIAZ": 2.191302984058232, "TOZINAMERAN": 1.2993225195295528, "TWINRIX": 1.0569213528141774, "VFEND": 2.146992894476139, "VIAGRA": 1.4547435514019744, "VIMPAT": 1.6925280447404591, "VORICONAZOLE": 1.1142994818058125, "XELJANZ": 1.124625005895669, "ZYPADHERA": 11.555275411917076, "ZYPREXA": 2.3416074504669715, "null": 2.0742455837524605}
\ No newline at end of file
+{"ABILIFY": 1.483535315446062, "ARIPIPRAZOLE": 0.9602444192863924, "BENZODIAZEPINE": 11.58012151830402, "BIKTARVY": 2.1669781331918214, "BRINTELLIX": 0.8945343324673007, "BUPRENORPHINE": 20.78114404614233, "COMIRNATY": 0.0229384785613317, "CYMBALTA": 0.5809545680205694, "DULOXETINE": 2.280841633549234, "FENTANYL": 5.747409636462709, "IBUPROFEN": 2.6745878246892283, "KEPPRA": 2.1302331192813435, "LANTUS": 0.2346269965008762, "LYRICA": 4.5529520558998975, "MIDAZOLAM": 5.535107337718267, "NALOXONE": 65.87776609155605, "OLANZAPINE": 9.238745818241592, "PREGABALIN": 16.023784940724276, "SODIUM": 51.29912456556964, "SPIKEVAX": 0.0485715884454621, "SUBOXONE": 4.720513059383187, "SUFENTANIL": 9.856369291838975, "TOZINAMERAN": 0.0630460521715235, "VAXZEVRIA": 0.050087477543117, "VFEND": 1.0246277658848215, "ZYPADHERA": 7.962094257083629, "ZYPREXA": 6.142805859887483, "null": 5.607750137202185}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7659.json
index 57427c7713e..99138cdcd83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7659.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7659.json
@@ -1 +1 @@
-{"COMBIVIR": 6.2945091065344405, "EPIVIR": 12.35470784800599, "INFANRIX": 32.63828990591097, "KEPPRA": 2.3775963747562257, "MMRVAXPRO": 5.725840820502728, "PREVENAR": 20.707825926869564, "SUBOXONE": 6.975176944509329, "null": 7.489764164517793}
\ No newline at end of file
+{"HUMAN": 440.5866493491976, "null": 1.1010067012107208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/766.json
index 49c6a0a6a24..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/766.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/766.json
@@ -1 +1 @@
-{"GARDASIL": 27.682357980940907}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7660.json
index ec8b6197b2a..8939134eb1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7660.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7660.json
@@ -1 +1 @@
-{"null": 3.899849023501064}
\ No newline at end of file
+{"ANORO": 803.6621048435467, "APIXABAN": 128.45666550346377, "AZATHIOPRINE": 34.47290653715975, "BUDESONIDE": 2.686086385281484, "COMIRNATY": 0.2368460787419694, "MEPOLIZUMAB": 15.737469305911237, "SPIKEVAX": 0.2324085703148389, "null": 0.1764527904290462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7661.json
index 7efa8018aa3..11ef01615a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7661.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7661.json
@@ -1 +1 @@
-{"null": 3.5148518229747605}
\ No newline at end of file
+{"INTELENCE": 4803.567854497512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7662.json
index 9afadd589cc..2e55e872ab3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7662.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7662.json
@@ -1 +1 @@
-{"null": 4.944488428517633}
\ No newline at end of file
+{"BIKTARVY": 106.42441620614947, "DEXAMETHASONE": 140.16454562775766, "LEVETIRACETAM": 48.901741466100425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7663.json
index 301708045d1..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7663.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7663.json
@@ -1 +1 @@
-{"null": 3.791598180341608}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7664.json
index 314d08b4d2e..ec1b290e53e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7664.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7664.json
@@ -1 +1 @@
-{"null": 2.059807064143012}
\ No newline at end of file
+{"ABACAVIR": 15.408894107948033, "ATRIPLA": 1.5643939763654, "COMBIVIR": 52.83260521541753, "COMIRNATY": 1.763201627817221, "INVIRASE": 188.1958555668036, "VIREAD": 34.07459120981709, "null": 0.3176099212416751}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7665.json
index 3bedfe5c5a6..9ce07f4f63f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7665.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7665.json
@@ -1 +1 @@
-{"null": 3.633047121257831}
\ No newline at end of file
+{"null": 2.0370311496868565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7666.json
index aae63993a27..5db20dc5145 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7666.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7666.json
@@ -1 +1 @@
-{"null": 3.253302696462397}
\ No newline at end of file
+{"null": 2.846137987720282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7667.json
index 79d92a4fc76..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7667.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7667.json
@@ -1 +1 @@
-{"null": 1.3193243928001126}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7668.json
index e5d65fcfa51..799c29b7ad7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7668.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7668.json
@@ -1 +1 @@
-{"null": 3.05826723229333}
\ No newline at end of file
+{"ABACAVIR": 154.91757398474897, "COMIRNATY": 0.5599277211311883, "null": 0.484238120492352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7669.json
index c3d9becbc4e..e19f1f69d7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7669.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7669.json
@@ -1 +1 @@
-{"null": 1.1464456165419163}
\ No newline at end of file
+{"INTELENCE": 1634.87883964271}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/767.json
index a1731d26ccf..b50c0d3fa8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/767.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/767.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 54.66889530640226, "ARANESP": 1.787659688014277, "BEVACIZUMAB": 2.5829495728601635, "BUSULFAN": 14.26162216381147, "CICLOSPORIN": 10.651170440571963, "ENTYVIO": 2.624947056212548, "HUMAN": 14.266866150918984, "IPILIMUMAB": 13.880022687975002, "JAKAVI": 3.059429832041717, "KEYTRUDA": 6.385468127553972, "LEMTRADA": 18.53816870563779, "LEVOFLOXACIN": 2.2586392446645185, "MABCAMPATH": 57.82679205829911, "NOVONORM": 21.04589928996799, "OPDIVO": 4.155068233475303, "PEGASYS": 5.221186678051403, "PEGINTERFERON": 8.787393852965156, "PEGINTRON": 4.711918642980698, "PEMBROLIZUMAB": 11.953762954989994, "PRIVIGEN": 3.6635580061077113, "RIBAVIRIN": 3.329684294857318, "RITUXIMAB": 4.599631440746169, "SOLIRIS": 1.5127808911144736, "TAMIFLU": 2.522531017769136, "VENCLYXTO": 33.438318546870654, "VENETOCLAX": 35.89574560852182}
\ No newline at end of file
+{"null": 9.640797881627122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7670.json
index 71f8b1d8a7e..250e8d7e4d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7670.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7670.json
@@ -1 +1 @@
-{"null": 4.571983757171695}
\ No newline at end of file
+{"ABACAVIR": 169.22159041294174, "ATAZANAVIR": 116.359756997996, "ATRIPLA": 0.8387550347480646, "CRIXIVAN": 171.58590705123788, "ENFUVIRTIDE": 579.3875928474247, "IBUPROFEN": 6.2847230363399085, "INTELENCE": 108.03239645820874, "KALETRA": 16.355001846582013, "LAMIVUDINE": 45.18824138855129, "RIBAVIRIN": 11.496602397107832, "SAQUINAVIR": 1873.104789775333, "TRUVADA": 1.2455015607996498, "null": 0.0876787001299883}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7671.json
index e4b2652f84c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7671.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7671.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7672.json
index 4fd214e684a..796e6f23fc0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7672.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7672.json
@@ -1 +1 @@
-{"COMIRNATY": 2.1194834023214177, "COVID19": 1.066938252678964, "VAXZEVRIA": 1.9241225417958137}
\ No newline at end of file
+{"null": 2.039075616916378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7673.json
index f9914422e94..cca28b7ecfa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7673.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7673.json
@@ -1 +1 @@
-{"COMBIVIR": 28.548484528546588, "DARUNAVIR": 34.25068771593388, "DEXAMETHASONE": 2.5860478093969523, "KEPPRA": 4.085662797612101, "LEVETIRACETAM": 8.011296812519875, "null": 9.307881668398927}
\ No newline at end of file
+{"null": 1.4682950408366553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7674.json
index bab2207eac0..79bd8ee3106 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7674.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7674.json
@@ -1 +1 @@
-{"null": 6.846316635349547}
\ No newline at end of file
+{"AVANDIA": 15.396607845184848, "CLOPIDOGREL": 3.0406105475462653, "COMIRNATY": 0.0767335824700252, "ELIQUIS": 10.49804329389731, "FYCOMPA": 34.563785348141884, "null": 1.6176150301902277}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7675.json
index 60cebce6e7b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7675.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7675.json
@@ -1 +1 @@
-{"null": 2.075593092528214}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7676.json
index 4e909c5b573..309acd975ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7676.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7676.json
@@ -1 +1 @@
-{"null": 3.0390232848659395}
\ No newline at end of file
+{"AFINITOR": 1.4953246833605434, "APIXABAN": 2.8228258552723737, "APROVEL": 5.841482451100019, "ARIPIPRAZOLE": 3.929280465642666, "AVANDAMET": 8.707804642688046, "AVANDIA": 9.88420787721383, "BEDAQUILINE": 5.812120385904112, "BRILIQUE": 5.298824811563168, "BUMETANIDE": 42.96962464155932, "BYETTA": 0.9155305067766228, "CELECOXIB": 2.9873960499119057, "CELLCEPT": 0.9295108804555549, "CICLOSPORIN": 0.4780470460049928, "CLOPIDOGREL": 2.9012409548876565, "COMIRNATY": 0.3347120544300576, "CYMBALTA": 0.3712292620622244, "DAPAGLIFLOZIN": 19.106363225878475, "DASATINIB": 11.946417822285056, "DOCETAXEL": 1.220051713651655, "DULOXETINE": 2.4105420685798906, "EDOXABAN": 46.28210752070248, "ELIQUIS": 2.533981342975166, "EMPAGLIFLOZIN": 4.298817735758627, "ENTRESTO": 12.87866634901938, "EVISTA": 3.2733921116850384, "EXJADE": 1.2151065046134228, "FENTANYL": 0.5725286632510223, "FORSTEO": 1.1642005671322222, "GARDASIL": 0.5351979897528432, "HERCEPTIN": 5.941691618514279, "ICLUSIG": 4.1329524260223565, "INTEGRILIN": 15.995202876832636, "IRBESARTAN": 6.211170183147972, "IVABRADINE": 35.82421899676855, "JANUVIA": 1.5078491486858814, "JARDIANCE": 0.611156732692016, "KALETRA": 1.3779170866792505, "NAGLAZYME": 18.558064266761303, "OLANZAPINE": 0.8578746605822309, "PANTOPRAZOLE": 3.511088682234445, "PEGASYS": 0.3867864256885258, "SOLIRIS": 0.8438560046087494, "SPIKEVAX": 0.2829582417708109, "SPIRONOLACTONE": 6.87789401907722, "SUTENT": 0.3366524772549242, "TASIGNA": 6.2551679050093405, "TOZINAMERAN": 0.1310836177268025, "VALSARTAN": 17.814205263909184, "VAXZEVRIA": 0.052943902189011, "VIAGRA": 0.9932880284481244, "XOLAIR": 1.1019255633102856, "ZOSTAVAX": 2.440801178393732, "ZYPREXA": 1.2405942062573911, "null": 1.6877188137029022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7677.json
index 9c9455131c5..c92767a1cb6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7677.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7677.json
@@ -1 +1 @@
-{"ARAVA": 1.712260436452956, "ATRIPLA": 5.472019407686605, "FORSTEO": 6.148992879148731, "HUMALOG": 3.457693431630662, "LYRICA": 6.659320175476379, "SUTENT": 1.2366727535818942, "TRUVADA": 1.6794610440505455, "XELJANZ": 2.1681627589116794, "null": 1.1080803520926292}
\ No newline at end of file
+{"AVANDIA": 5.6126197414567605, "AVONEX": 127.31548808119884, "COMIRNATY": 0.4871098081416489, "SPIKEVAX": 0.2499700674919231, "VAXZEVRIA": 0.191736524173392, "ZOSTAVAX": 3.7013680664379502, "null": 1.9120549745642152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7678.json
index 4444f7d5fd7..961e09dafd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7678.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7678.json
@@ -1 +1 @@
-{"ABRAXANE": 11.192615021638726, "AFINITOR": 2.363545785844253, "ATRIPLA": 7.208886660711597, "AZATHIOPRINE": 2.90366414692523, "BONVIVA": 11.53334467187501, "BUPIVACAINE": 17.581425787668437, "CELLCEPT": 1.0389282537562128, "CICLOSPORIN": 1.2851246929668625, "DEXAMETHASONE": 1.907553394882733, "ELIQUIS": 1.3044413340413914, "ENZALUTAMIDE": 11.137412704764388, "EVENITY": 98.82642522688928, "EVISTA": 24.29755644683253, "FASLODEX": 1.4061497009895845, "FORSTEO": 5.697580988489302, "HEPSERA": 9.72577058560791, "HUMIRA": 1.713147182597336, "IBRANCE": 1.4046802600685404, "KEYTRUDA": 1.2830442387875425, "LYRICA": 1.2386519149552773, "MEPOLIZUMAB": 1.5440135930223882, "METHOTREXATE": 2.693235562519605, "MIRABEGRON": 29.39997681632112, "NORVIR": 8.421295783284583, "REVLIMID": 7.863127376414269, "RINVOQ": 2.403045118314476, "SIMPONI": 3.0605558675745503, "STRIBILD": 8.189066809692145, "TERIPARATIDE": 18.35043349921976, "TRUVADA": 7.638610200442364, "VIREAD": 6.488513385059476, "XELJANZ": 1.6531737649920042, "XOFIGO": 15.676576970586376, "XTANDI": 3.104267528445399, "ZOSTAVAX": 1.4613712846196512}
\ No newline at end of file
+{"null": 1.141705649344067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7679.json
index a4a611d0826..5f4fd17c31c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7679.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7679.json
@@ -1 +1 @@
-{"BUMETANIDE": 1024.6447354191264}
\ No newline at end of file
+{"null": 1.176902031718418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/768.json
index be342bdf37f..6a3837a2241 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/768.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/768.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 1.939213779669799, "BETAFERON": 11.16210432686378, "CELLCEPT": 2.20094360978529, "EFAVIRENZ": 24.95958915522084, "ENTYVIO": 1.3830311571305312, "HARVONI": 3.150997217739466, "HUMIRA": 1.2957755897627492, "IBUPROFEN": 1.6755131450158267, "INLYTA": 2.383035737460913, "IPILIMUMAB": 51.54027169247216, "IRBESARTAN": 4.1307925051756245, "KAFTRIO": 3.8506893861534826, "KEYTRUDA": 14.567744735764007, "KISQALI": 4.662140448474119, "LEMTRADA": 7.082509170389333, "NIVOLUMAB": 17.757873940261966, "OPDIVO": 26.58098832801254, "PEGASYS": 4.425602181478599, "PEGINTERFERON": 12.574081858862918, "PEGINTRON": 8.120395641296605, "PEMBROLIZUMAB": 14.3734381364922, "RIBAVIRIN": 4.282821429664738, "SOVALDI": 4.34647692809549, "STELARA": 1.394802290281027, "TRACLEER": 3.228217651011847, "TWINRIX": 4.255827910464643, "VICTOZA": 2.5180574282031314, "YERVOY": 27.81665257726338}
\ No newline at end of file
+{"null": 2.7369647729532067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7680.json
index 9c8574db380..c63188b018e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7680.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7680.json
@@ -1 +1 @@
-{"AFINITOR": 2.34167965248125, "BENRALIZUMAB": 266.80019143419986, "BUPIVACAINE": 10.348519821492088, "CLOPIDOGREL": 4.474111210145527, "ELIQUIS": 1.4059379777582308, "FENTANYL": 2.840157926403608, "IBRANCE": 1.3916980288946903, "KEYTRUDA": 1.0655386920682608, "NAGLAZYME": 414.2270756115629, "NEXAVAR": 1.7081464871092336, "SIMPONI": 1.8017482995432712, "SUTENT": 1.7695055483425433, "XELJANZ": 1.763751714980836, "XOFIGO": 125.827529060048, "XTANDI": 10.221922409564849}
\ No newline at end of file
+{"null": 2.217935797520945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7681.json
index 51dd82fe7be..f8b253616f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7681.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7681.json
@@ -1 +1 @@
-{"SUTENT": 1.5123457089767378, "TOZINAMERAN": 1.0895839075509983, "null": 1.2188666620222175}
\ No newline at end of file
+{"ELIQUIS": 4.688527658951887, "null": 2.1187913171734016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7682.json
index 44decb5aebe..9b13b1b7ae6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7682.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7682.json
@@ -1 +1 @@
-{"ELIQUIS": 9.835001037496006, "PLAVIX": 11.912684503082938, "null": 2.4124778320994578}
\ No newline at end of file
+{"ENTRESTO": 147.5725274569521}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7683.json
index f50b912ab53..ca900578fa8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7683.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7683.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 15.616090848216595, "ELIQUIS": 32.358945230425725, "null": 1.0759747915026638}
\ No newline at end of file
+{"ATRIPLA": 1.2579292962490567, "COMIRNATY": 0.4770214334776482, "CYMBALTA": 2.346200108292282, "FORSTEO": 5.085042893945065, "GARDASIL": 2.7332632117912112, "KEPPRA": 3.578037899918793, "SPIKEVAX": 0.2656521801790336, "null": 1.0693696916174833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7684.json
index 6e93f4133a5..c0ad9408909 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7684.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7684.json
@@ -1 +1 @@
-{"null": 1.1646108727749316}
\ No newline at end of file
+{"COMIRNATY": 0.6608918641631826, "GARDASIL": 10.969720467285828, "null": 0.3206615860406053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7685.json
index 78314135286..0c9775254b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7685.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7685.json
@@ -1 +1 @@
-{"FENTANYL": 36.188196491705305}
\ No newline at end of file
+{"null": 0.7743032315660294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7686.json
index 82575da6895..446c817514a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7686.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7686.json
@@ -1 +1 @@
-{"ENBREL": 31.238532098190834}
\ No newline at end of file
+{"null": 0.9536240008229327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7687.json
index ace3588eeb5..48778da0fa3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7687.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7687.json
@@ -1 +1 @@
-{"ATRIPLA": 1.437764772323203, "BUPIVACAINE": 83.65888203080559, "COSENTYX": 10.174043451640424, "ELIQUIS": 1.6705751003905387, "FENTANYL": 13.478192536284284, "LANTUS": 2.1571694582739065, "null": 1.2190449986024685}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7688.json
index b0f488ba817..4c92e338036 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7688.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7688.json
@@ -1 +1 @@
-{"null": 4.705583054188087}
\ No newline at end of file
+{"COMIRNATY": 0.3340992291278267, "CYMBALTA": 2.686104286919186, "LANTUS": 2.4687471799959666, "MMRVAXPRO": 7.823572444570948, "OLANZAPINE": 4.474357966515993, "SPIKEVAX": 0.5555851962534027, "TOZINAMERAN": 0.7436250639677109, "VAXZEVRIA": 0.1672970541996002, "null": 1.490894982062023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7689.json
index e85722bc05a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7689.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7689.json
@@ -1 +1 @@
-{"null": 2.946876774685152}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/769.json
index 92093c9f266..6cc0aea1106 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/769.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/769.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 50.54028524505242, "IPILIMUMAB": 47.27680113505468, "KEYTRUDA": 47.03496572746179, "LEMTRADA": 50.51961394119918, "PEMBROLIZUMAB": 86.8681272190973}
\ No newline at end of file
+{"SIMPONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7690.json
index 15574012c4f..929c8e24e0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7690.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7690.json
@@ -1 +1 @@
-{"null": 4.406448101978552}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7691.json
index ac4dbaafa53..12881ae3247 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7691.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7691.json
@@ -1 +1 @@
-{"XTANDI": 16.244264038495704}
\ No newline at end of file
+{"OCALIVA": 3834.7455166239465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7692.json
index 06d40420602..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7692.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7692.json
@@ -1 +1 @@
-{"FENTANYL": 26.8421862078261, "null": 1.0193299428754987}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7693.json
index ba2613ad196..5861639d9b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7693.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7693.json
@@ -1 +1 @@
-{"null": 1.2229875075149683}
\ No newline at end of file
+{"MYCOPHENOLATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7694.json
index 14b2f99bd00..55c0c60ecd3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7694.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7694.json
@@ -1 +1 @@
-{"NAGLAZYME": 380.2819896299943}
\ No newline at end of file
+{"null": 9.520533978993594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7695.json
index 5e29fd471bf..8b47c3733f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7695.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7695.json
@@ -1 +1 @@
-{"ATRIPLA": 2.991122738699659, "SPINRAZA": 69.51131926309743, "null": 1.3663709555308785}
\ No newline at end of file
+{"NAGLAZYME": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7696.json
index e70cddc4ce5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7696.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7696.json
@@ -1 +1 @@
-{"ARAVA": 1.219687650842351, "AUBAGIO": 3.063876606651061, "BELIMUMAB": 58.04743129635512, "BENLYSTA": 2.8737229752042093, "COSENTYX": 2.3270778295164583, "ELIQUIS": 3.9220149930677817, "ENBREL": 1.6613632775542209, "EVENITY": 7.167093533958791, "EXFORGE": 2.7850237261793627, "FORSTEO": 7.635313217323497, "HUMALOG": 2.1759357036878173, "HUMIRA": 1.6275640640273303, "IBRANCE": 2.894286859712343, "LANTUS": 3.4331766071536385, "LYRICA": 12.688716992478335, "METHOTREXATE": 1.2594070355325002, "NAGLAZYME": 8.843543160869503, "OMALIZUMAB": 2.7783891928047044, "SIMPONI": 3.1933330024430013, "SPINRAZA": 9.500529832406912, "STRIBILD": 3.0617460029340062, "SUBOXONE": 1.952789016404652, "SUTENT": 2.265858888139252, "TOVIAZ": 6.368500708687698, "TRUVADA": 1.266695028130591, "VIAGRA": 7.662366685806326, "XELJANZ": 5.826334056620661, "ZOSTAVAX": 3.530377752061156, "null": 1.0076363388026683}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7697.json
index 51e1117bb98..e6f1387e436 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7697.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7697.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 83.51557605253906, "ELIQUIS": 4.989587882126978, "ENOXAPARIN": 23.772728495031576, "FENTANYL": 6.40767431183129, "PLAVIX": 4.902329017024855, "null": 1.927723575195494}
\ No newline at end of file
+{"null": 0.7428750911212086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7698.json
index 34e058d652a..db88e3e0635 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7698.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7698.json
@@ -1 +1 @@
-{"ENOXAPARIN": 315.80309364596945}
\ No newline at end of file
+{"DEXAMETHASONE": 14.978252956014533, "LAMIVUDINE": 209.13265569696145, "null": 0.4616019412538469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7699.json
index 3d64f70d981..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7699.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7699.json
@@ -1 +1 @@
-{"ATRIPLA": 5.709313813255997, "BIKTARVY": 1.4295939560459645, "BONVIVA": 5.619036141169437, "ELIQUIS": 1.881509471916936, "ENTRESTO": 1.31739872064069, "ESBRIET": 3.0525121170706724, "EVENITY": 70.15579788005445, "EVISTA": 28.279706739843384, "FASLODEX": 1.4352879396016378, "FORSTEO": 26.165878585346945, "HUMALOG": 1.868302025483256, "HUMIRA": 1.7410226399352593, "IBRANCE": 3.102523817966909, "IBUPROFEN": 1.4003369153969067, "INCRUSE": 3.305484729785217, "INSULIN": 1.149166739194358, "LANTUS": 1.3284113672721694, "LYRICA": 2.605942913916511, "OPSUMIT": 1.152565253513613, "PREOTACT": 50.47369314178402, "REVATIO": 4.019679794199031, "REVLIMID": 3.4720645662000407, "RINVOQ": 2.7059764409540894, "RITUXIMAB": 1.1152905253559229, "SIMPONI": 2.869207135299807, "STELARA": 1.0628948978977653, "STRIBILD": 9.637133745949392, "SUBOXONE": 3.165319355364661, "TERIPARATIDE": 13.013928960845346, "TOVIAZ": 1.585984192185797, "TRELEGY": 6.002283675855728, "TREMFYA": 1.7608557095094723, "TRUVADA": 6.203822384936808, "VIAGRA": 4.435105508680346, "VIREAD": 3.3640297252950155, "XELJANZ": 4.879635386933575, "XOLAIR": 1.175388089688303, "XTANDI": 1.955057222168462, "null": 1.086165048852617}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/77.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/77.json
index 6005cc0e197..2deb6cd9574 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/77.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/77.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 17.409660782481858, "IBUPROFEN": 2.044057906214277, "INVOKANA": 16.224040042189866, "KEPPRA": 2.6672596517651765, "OLANZAPINE": 5.823193115990974, "SUBOXONE": 51.65871949058116, "VIAGRA": 4.213169256520356, "ZYPREXA": 1.9744171229992933, "null": 5.137167934321396}
\ No newline at end of file
+{"COMIRNATY": 1.6692280880702166}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/770.json
index e845c82e36a..a3450eba32e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/770.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/770.json
@@ -1 +1 @@
-{"KEYTRUDA": 45.09458878332744}
\ No newline at end of file
+{"ZOSTAVAX": 31.48026766407909, "null": 0.6184948816365008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7700.json
index 78b7ad2e957..e0422ef7a81 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7700.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7700.json
@@ -1 +1 @@
-{"ABATACEPT": 4.4837285779646905, "ADALIMUMAB": 1.2516752133406912, "AMINOSALICYLIC": 19.360580322737803, "ARAVA": 1.195182827430597, "ATRIPLA": 2.307573067065805, "CIMZIA": 2.447243175760893, "COMBIVIR": 47.60456060859282, "COSENTYX": 2.397518654080057, "CYMBALTA": 3.654433603404952, "HUMALOG": 1.9835146872670009, "LYRICA": 4.60852882996694, "OMALIZUMAB": 8.48743125488445, "SPINRAZA": 18.415399745440105, "STELARA": 3.3247838865896604, "TRUVADA": 1.581176055047982, "XELJANZ": 4.389588832457066, "ZOSTAVAX": 8.847521952088963}
\ No newline at end of file
+{"BIKTARVY": 572.2812317977036}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7701.json
index 90384f8d306..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7701.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7701.json
@@ -1 +1 @@
-{"SPINRAZA": 859.3049643898396}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7702.json
index 0c28ad428ae..119a2bb2b4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7702.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7702.json
@@ -1 +1 @@
-{"ATRIPLA": 1.9759752028803037, "null": 1.1120545123292072}
\ No newline at end of file
+{"COMIRNATY": 0.7469343348211291, "SPIKEVAX": 0.4046347117529743, "null": 0.6551076946701784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7703.json
index d6f481a6b3c..452e4b93a14 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7703.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7703.json
@@ -1 +1 @@
-{"null": 1.043373384120751}
\ No newline at end of file
+{"DARZALEX": 203.9453988685196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7704.json
index 9a6a767f821..fee9097f97e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7704.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7704.json
@@ -1 +1 @@
-{"SPINRAZA": 3483.2606846503195}
\ No newline at end of file
+{"DARZALEX": 85.2101406936284, "null": 1.1569156161452918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7705.json
index 2d115af057a..7d8774334c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7705.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7705.json
@@ -1 +1 @@
-{"AUBAGIO": 9.62756665276687, "BENLYSTA": 4.886626512723302, "BUPRENORPHINE": 1.4324813333840214, "BYETTA": 4.561501882742915, "CIMZIA": 3.3136999440473653, "CYMBALTA": 1.1991341908322088, "ELIQUIS": 1.0329324132140247, "ENBREL": 1.7448486559967789, "EVENITY": 9.317071321301713, "FENTANYL": 1.1455711802922377, "HIZENTRA": 6.173474807894262, "IBRANCE": 3.0322231324572217, "JANUMET": 6.773576666071012, "JANUVIA": 3.270677319000443, "JARDIANCE": 1.858039223210972, "LANTUS": 6.268458929239602, "LEVEMIR": 2.087569562098111, "LYRICA": 3.125322458117241, "NAGLAZYME": 12.341751546978166, "NUCALA": 1.5477134756394522, "OPSUMIT": 1.2916529776180776, "RINVOQ": 5.40908461664921, "SIMPONI": 8.220899970821801, "STELARA": 3.3326781896760944, "SUBOXONE": 1.4867056591148926, "TRACLEER": 1.50485852295716, "TRELEGY": 2.4138276100422136, "TREMFYA": 10.558274933026576, "VELTASSA": 8.799023127062497, "XELJANZ": 8.364108399666158, "XTANDI": 2.4496477590400207, "ZOSTAVAX": 7.114843973902861, "null": 1.6971779817247028}
\ No newline at end of file
+{"ANAKINRA": 4466.618623446605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7706.json
index 626cdb844ab..f597b4cdf6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7706.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7706.json
@@ -1 +1 @@
-{"ADENURIC": 10.772252213981892, "ATRIPLA": 10.124938645459425, "BUPRENORPHINE": 3.0141828150622616, "BYETTA": 4.104653180950861, "CIMZIA": 1.1361213579246283, "COSENTYX": 3.490399788800685, "ENBREL": 4.797820786853481, "EVISTA": 5.703154097724782, "HUMIRA": 4.695183799158509, "JANUMET": 10.247926472208215, "JANUVIA": 8.610673112766573, "KEYTRUDA": 1.1424887889748865, "LYRICA": 1.7446606640320703, "METHOTREXATE": 1.1880772160219712, "STRIBILD": 8.63799507832165, "TRUVADA": 6.650934553243771, "VIREAD": 4.147915273253359, "XELJANZ": 2.2351817474495044, "ZOSTAVAX": 14.013917365510688}
\ No newline at end of file
+{"null": 0.2758322208109772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7707.json
index 7438cab0f7d..2f0ae0a1b3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7707.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7707.json
@@ -1 +1 @@
-{"AFINITOR": 1.8430660979056208, "BENLYSTA": 1.245828322081537, "BIKTARVY": 1.889181051285208, "BONVIVA": 5.677309521948742, "BUPIVACAINE": 3.986207676866142, "BYDUREON": 1.5829360057977433, "COMIRNATY": 1.520771577980601, "COSENTYX": 5.867844456714221, "COVID19": 1.4023096131621038, "DOCETAXEL": 1.4015242538801953, "ENBREL": 2.1357390169729804, "ENTYVIO": 1.0905989174442563, "EXFORGE": 1.4974185349948843, "FASLODEX": 1.1425151677540315, "FLEBOGAMMA": 5.6353014240831865, "FORSTEO": 9.959901018564103, "FULVESTRANT": 5.987144827668145, "HUMIRA": 1.7341905764159715, "IBRANCE": 2.1381730449540424, "JAKAVI": 1.044118597855317, "KISQALI": 3.1869202919652992, "LYRICA": 1.5678647875809857, "NAGLAZYME": 3.490641462680023, "NEULASTA": 4.518070733397255, "PEMBROLIZUMAB": 1.2154467078535414, "RINVOQ": 2.1086057426790688, "ROACTEMRA": 1.7347302593953438, "SHINGRIX": 1.4951531776689606, "SIMPONI": 2.0865054384186266, "SPINRAZA": 3.7459468304097903, "SUTENT": 1.1100916495568138, "TOZINAMERAN": 1.2673685096283889, "TWINRIX": 1.8864436786074543, "VAXZEVRIA": 1.5837562760734183, "XELJANZ": 1.514196402810523, "XOFIGO": 5.5720946801880205}
\ No newline at end of file
+{"ALEMTUZUMAB": 21.309170841325383, "CICLOSPORIN": 4.35415399192147, "COMIRNATY": 0.1962435632789425, "IBRANCE": 8.703226265953472, "LEMTRADA": 38.04014477140793, "null": 0.7215041992477691}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7708.json
index 15aa1aabb64..2b6d47066ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7708.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7708.json
@@ -1 +1 @@
-{"ACLASTA": 27.86975414761918, "ANAKINRA": 2.73631308061473, "ARAVA": 1.5122536586599729, "ATRIPLA": 5.517703497010627, "BIKTARVY": 3.0894805104016254, "BUPIVACAINE": 12.82591703795982, "BUPRENORPHINE": 3.0566813428185005, "BUSULFAN": 6.296922416291861, "BYETTA": 1.7726412964858298, "CIMZIA": 4.36921179170128, "COSENTYX": 2.700813243213789, "ELIQUIS": 1.7570008122077765, "ENBREL": 2.6885898959582764, "FASLODEX": 1.926280727343377, "FORSTEO": 1.5613209679488256, "HARVONI": 5.399517603808179, "HUMALOG": 3.14089492460239, "HUMIRA": 2.072433350261212, "IBRANCE": 1.0027995578485795, "LANTUS": 1.799039636413461, "LEVEMIR": 3.1765705964814805, "LYRICA": 3.167852980412283, "METHOTREXATE": 30.651788473055056, "NAGLAZYME": 8.016393608331835, "PANTOPRAZOLE": 6.454710541672579, "RINVOQ": 2.9068184478525096, "SIMPONI": 1.1072869931651068, "STELARA": 1.800007754472635, "STRIBILD": 3.0833051558831768, "SUBOXONE": 1.298859222978724, "TRUVADA": 1.976052727376297, "XELJANZ": 4.517192979728206, "ZOSTAVAX": 5.8646668845195125}
\ No newline at end of file
+{"ABATACEPT": 6.664675665738876, "ADALIMUMAB": 1.8612685275802443, "ARIPIPRAZOLE": 5.405187301206565, "AUBAGIO": 4.329455765541903, "COMIRNATY": 0.2871932025170551, "ENBREL": 4.323145414416083, "EXJADE": 5.627645872578109, "IBRANCE": 2.8840458008700565, "JAKAVI": 4.314703907947692, "MEPOLIZUMAB": 3.756951696004841, "METHOTREXATE": 3.662144110433146, "PEGASYS": 1.163148190219845, "PEGINTERFERON": 5.066591548712127, "RUXOLITINIB": 22.491540704952385, "TOZINAMERAN": 0.787059234592058, "ZOSTAVAX": 1.7847689622766574, "null": 0.6963250618437854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7709.json
index c130107a59c..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7709.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7709.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 101.41288873084667}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/771.json
index 119719e5865..994c96bb488 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/771.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/771.json
@@ -1 +1 @@
-{"KEYTRUDA": 71.32749894264413}
\ No newline at end of file
+{"VAXZEVRIA": 14.912640545494018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7710.json
index 59b4724d1d4..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7710.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7710.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 18.597963196437632, "null": 2.42382439768555}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7711.json
index fd33b36699d..9d26496db9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7711.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7711.json
@@ -1 +1 @@
-{"COMBIVIR": 518.9109229694644}
\ No newline at end of file
+{"LEMTRADA": 200.0395778631197, "null": 0.3912703338460954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7712.json
index 4339a21ec71..24dcebc6e60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7712.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7712.json
@@ -1 +1 @@
-{"APIXABAN": 53.30593350969661, "AZATHIOPRINE": 124.58187121052684, "IBUPROFEN": 21.02187982863005, "MEPOLIZUMAB": 25.059637481166327, "NUCALA": 14.517285159092827, "OMALIZUMAB": 64.87998153114833, "XOLAIR": 9.540569282855714}
\ No newline at end of file
+{"ALEMTUZUMAB": 85.04472138539107, "IBRANCE": 6.399505226588549, "OMALIZUMAB": 35.513330891210984, "null": 0.3213003177301815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7713.json
index 1971c0f2a25..9e36c29470d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7713.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7713.json
@@ -1 +1 @@
-{"null": 1.9804792314952493}
\ No newline at end of file
+{"null": 1.037185294654559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7714.json
index eadb2204693..572cf2b8d35 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7714.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7714.json
@@ -1 +1 @@
-{"EXJADE": 7.493857235430455, "JAKAVI": 82.31056767861236, "RUXOLITINIB": 54.863923691472905, "null": 1.0309338310334928}
\ No newline at end of file
+{"COMIRNATY": 0.1604699491134718, "null": 1.3238066879028338}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7715.json
index e4b2652f84c..595a97d8e4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7715.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7715.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"COMIRNATY": 1.4934669853906186, "VAXZEVRIA": 0.5711392150008487, "null": 0.6540482869747573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7716.json
index 522766d738c..ed67aabaf19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7716.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7716.json
@@ -1 +1 @@
-{"BYETTA": 35.15420405709042, "CICLOSPORIN": 4.200036732450712, "EXJADE": 15.402495212187567, "JANUMET": 38.50342442471683, "JANUVIA": 24.422277086002293, "NPLATE": 311.73620254576184, "STELARA": 4.877480320874592}
\ No newline at end of file
+{"COMIRNATY": 0.8489895180669974, "null": 0.6468042779807913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7717.json
index 68f70002386..7f5802f1ab9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7717.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7717.json
@@ -1 +1 @@
-{"CICLOSPORIN": 11.400612544129594}
\ No newline at end of file
+{"COMIRNATY": 0.4730912500577175, "PEGASYS": 5.523378368757425, "PEGINTRON": 13.961157350823347, "TELMISARTAN": 120.48405403877672, "null": 1.080029702945961}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7718.json
index a6da895abca..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7718.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7718.json
@@ -1 +1 @@
-{"COVID19": 2.8840153025405595}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7719.json
index 4cae4d6d23d..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7719.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7719.json
@@ -1 +1 @@
-{"ADENURIC": 480.0525267081996}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/772.json
index 31001ba2d23..ad06656eb2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/772.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/772.json
@@ -1 +1 @@
-{"COMIRNATY": 2.722567538945547, "KEYTRUDA": 26.657440097987852}
\ No newline at end of file
+{"COMIRNATY": 1.8565084945216337, "SPIKEVAX": 0.7816801563828487, "TOZINAMERAN": 0.8865038009769288, "VAXZEVRIA": 1.074974975998445, "null": 0.559798966243322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7720.json
index da762ceecd5..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7720.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7720.json
@@ -1 +1 @@
-{"ELIQUIS": 15.90512194039946, "PLAVIX": 15.067286629194433}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7721.json
index acdeb413673..affb5be5397 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7721.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7721.json
@@ -1 +1 @@
-{"CYMBALTA": 1.3970683935418475, "ELIQUIS": 1.8857181932850644, "JAKAVI": 22.64741060738836, "PEGINTRON": 2.61026036006261, "RUXOLITINIB": 33.47677254032047}
\ No newline at end of file
+{"MIDAZOLAM": 226.56864166226225, "null": 1.086724205725813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7722.json
index 53da6a0ad15..16734cd7ac3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7722.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7722.json
@@ -1 +1 @@
-{"ADENURIC": 237.83925840689983, "AFINITOR": 20.32572320793658}
\ No newline at end of file
+{"AUBAGIO": 1.9253661096314136, "CLOPIDOGREL": 1.5910918758250112, "COMIRNATY": 2.492818854207944, "ELIQUIS": 0.6536406184159583, "GARDASIL": 3.207761190666808, "LANTUS": 0.6651201815178334, "PEGASYS": 0.5687052826091107, "SHINGRIX": 1.3764334286972577, "SPIKEVAX": 0.983110274899336, "TOZINAMERAN": 1.1908088448559755, "VAXZEVRIA": 1.8923641777844264, "null": 0.4039966758415514}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7723.json
index 3cdb44eca30..ad74341d2a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7723.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7723.json
@@ -1 +1 @@
-{"ADENURIC": 943.002815407432}
\ No newline at end of file
+{"AVANDIA": 0.6682286975527925, "CLOPIDOGREL": 0.8214940048949658, "COMBIVIR": 3.015751250058257, "COMIRNATY": 1.7329925473437875, "CYMBALTA": 0.2946318208736952, "ELIQUIS": 0.680372546504354, "EYLEA": 1.9679047340323728, "FENTANYL": 1.4806995238185532, "FORSTEO": 1.3219872042430267, "GARDASIL": 5.566736809569423, "HUMALOG": 0.7433629562916917, "IBRANCE": 0.5403480586323224, "KEYTRUDA": 0.4189653473033486, "LANTUS": 0.730055760604576, "NEXAVAR": 0.5930711246668084, "PLAVIX": 0.5472711092255526, "SHINGRIX": 3.3483534982745744, "SIMPONI": 0.9642668751396862, "SPIKEVAX": 1.1588325378486115, "STELARA": 0.5634629033918556, "SUTENT": 0.8508637267007232, "TOZINAMERAN": 2.4893079930764737, "TWINRIX": 4.35447158336323, "VAXZEVRIA": 1.3044955345879798, "VOTRIENT": 0.97418267834298, "XELJANZ": 0.4485183923260765, "null": 0.8025789070881624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7724.json
index 9ebdb15d108..9cf2cbedaea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7724.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7724.json
@@ -1 +1 @@
-{"ELIQUIS": 2.7864925027583625, "FILGRASTIM": 32.08687973890925, "JAKAVI": 48.17878116022661, "NEULASTA": 64.89457263759789}
\ No newline at end of file
+{"LEVETIRACETAM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7725.json
index f0b3a7f92c3..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7725.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7725.json
@@ -1 +1 @@
-{"JANUMET": 148.60633613935835}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7726.json
index 3a8afbe5de6..ff37dd2780c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7726.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7726.json
@@ -1 +1 @@
-{"COVID19": 2.015084299210519, "JANUMET": 36.03663228986306, "JANUVIA": 13.084852943744393, "VAXZEVRIA": 2.1277878191710213}
\ No newline at end of file
+{"ABILIFY": 2.9531634330031737, "AERIUS": 2.443635101673599, "AIMOVIG": 0.5205284722176695, "ARAVA": 0.0831987610523992, "ARIPIPRAZOLE": 4.222074858782516, "AUBAGIO": 0.8504981533947403, "BENLYSTA": 0.9393039758818884, "BIKTARVY": 1.285814741566888, "BOTULINUM": 3.183912722646456, "BRINTELLIX": 3.076159165669891, "BRIVIACT": 6.038663098525994, "BUPRENORPHINE": 0.7852347980275339, "CELECOXIB": 4.028828927031591, "CHAMPIX": 24.553460101514187, "CICLOSPORIN": 0.3562910032207705, "CIMZIA": 0.2601678867060715, "COMIRNATY": 0.4108025325658453, "COSENTYX": 0.5771705402104056, "CYMBALTA": 1.9751773128030417, "DEXAMETHASONE": 0.3580978503507583, "DULOXETINE": 1.8956595524695612, "ELLAONE": 3.743010773041569, "ENBREL": 0.4930715840397529, "FENTANYL": 1.2073274578007238, "FORSTEO": 1.196919516868291, "FYCOMPA": 12.627323155305202, "GARDASIL": 0.8651050172377055, "HUMALOG": 0.314253539659494, "HUMIRA": 0.4777575426139411, "IBRANCE": 0.9166091016402784, "INCIVO": 0.9262101501463004, "KAFTRIO": 7.65757042140317, "KEPPRA": 5.548956327091579, "LANTUS": 0.2938022372872381, "LATUDA": 4.688870847023732, "LEMTRADA": 2.371432110116705, "LEVETIRACETAM": 5.388692778598893, "LEVODOPA": 4.0301309454851015, "LEVOFLOXACIN": 0.4241466007810739, "LYRICA": 1.5480519440601832, "MMRVAXPRO": 1.4961392408377825, "OLANZAPINE": 2.07419135758458, "PANTOPRAZOLE": 2.554117111739907, "PEGASYS": 3.9170019104844354, "PEGINTERFERON": 3.1912271811445683, "PEGINTRON": 2.5368567787863925, "PLEGRIDY": 1.552131742694234, "PREVENAR": 6.940104640211494, "RIBAVIRIN": 1.6804812862219265, "RISPERIDONE": 3.062818842060969, "ROTATEQ": 1.1765008717129073, "SAXENDA": 1.7867187072904924, "SPIKEVAX": 0.2065372633827445, "STELARA": 0.3518909197546263, "STRIBILD": 0.3814327443076361, "SUBOXONE": 1.6476658877443773, "SUTENT": 0.5019058884022036, "TAMIFLU": 1.8689087426209232, "TOZINAMERAN": 0.4575697341974288, "TRIUMEQ": 3.3596108684714348, "TRUVADA": 0.1130662890432711, "VARENICLINE": 7.970782773944391, "VAXZEVRIA": 0.3590050000563777, "VIMPAT": 2.6923124794718207, "XELJANZ": 0.230161833248478, "XOLAIR": 0.3318096778088985, "XTANDI": 0.7198643502505232, "XYREM": 2.380997367637278, "ZOSTAVAX": 0.2569942921786265, "ZYPREXA": 0.8806364707980127, "null": 1.799529918155213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7727.json
index ae37c789a9d..dbd5b1d805c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7727.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7727.json
@@ -1 +1 @@
-{"ADCIRCA": 5.445091695802707, "ANAGRELIDE": 66.15655087495634, "ANAKINRA": 3.927239345850542, "ARANESP": 2.400867898159191, "ARIPIPRAZOLE": 1.07713289174711, "AVASTIN": 2.796556488944058, "AZACITIDINE": 6.040376250849704, "AZATHIOPRINE": 4.46097998486924, "BEVACIZUMAB": 3.538136184408017, "BUSULFAN": 2.0479511522766205, "BYETTA": 1.6095842484435676, "CELLCEPT": 1.8902027310043477, "CICLOSPORIN": 4.990282906307159, "COMBIVIR": 4.313373918308522, "CYTARABINE": 3.441761004046104, "DASATINIB": 7.765346958783179, "DEXAMETHASONE": 1.4916869369232255, "EFAVIRENZ": 3.8518548863923776, "EXJADE": 10.18890036612246, "EXVIERA": 5.306851448982666, "GAZYVARO": 5.186336641566154, "GLIVEC": 4.059251768089615, "HIZENTRA": 1.2664566759488387, "HYDROXYCARBAMIDE": 48.70300139290743, "IBRUTINIB": 14.468967682550687, "ICLUSIG": 2.951571122237291, "IMATINIB": 6.260347917411717, "JAKAVI": 98.30616730863356, "JANUMET": 1.3066972195034974, "JANUVIA": 1.7005830328038478, "KALETRA": 1.806318234928259, "KYMRIAH": 1.5863105669941042, "LAMIVUDINE": 7.7809052219685775, "LEMTRADA": 2.048809668767644, "LEVETIRACETAM": 1.2726596312399274, "MABTHERA": 4.46286423994748, "MERCAPTOPURINE": 4.737562928803312, "METFORMIN": 15.579364799229324, "MYCOPHENOLATE": 2.2510055548893777, "NEULASTA": 2.4977526448599527, "NILOTINIB": 9.987489118933468, "NPLATE": 8.178013985838023, "OCALIVA": 6.826762285652174, "OLANZAPINE": 1.0131239460920307, "OZEMPIC": 9.55335328112592, "PEGASYS": 3.061192303909928, "PEGINTRON": 1.0503759889442617, "RITUXIMAB": 1.6521595951051848, "RUXOLITINIB": 88.1432121065915, "SOLIRIS": 3.8200350769207656, "SPRYCEL": 4.41534119793763, "STELARA": 1.2805037422618053, "TASIGNA": 4.732481892346645, "VENCLYXTO": 9.042304972113335, "VENETOCLAX": 9.377468403728365, "null": 1.0049493561667877}
\ No newline at end of file
+{"null": 0.8179166441563179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7728.json
index 0423771ea13..89190207607 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7728.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7728.json
@@ -1 +1 @@
-{"COVID19": 1.6927196151642077}
\ No newline at end of file
+{"ABILIFY": 1.922509874649797, "AIMOVIG": 0.705436408381876, "ARAVA": 0.2342082073512582, "ARIPIPRAZOLE": 0.7110812316244817, "ATRIPLA": 0.1539456230812227, "AUBAGIO": 0.3537857039511753, "BIKTARVY": 0.8907931713580811, "BRINTELLIX": 2.0563012662870475, "BRIVARACETAM": 8.259207953150085, "BRIVIACT": 12.34908179675857, "BUPRENORPHINE": 1.9726343420009105, "CELLCEPT": 0.5369230557656481, "CHAMPIX": 20.842103167413807, "CIMZIA": 0.2759159430385093, "COMIRNATY": 0.5140000846676304, "COSENTYX": 0.5054324539096315, "CYMBALTA": 23.309937717599205, "DAKLINZA": 3.988207913442861, "DULOXETINE": 1.5766804779052774, "ELIQUIS": 0.399490614944659, "ELLAONE": 19.94721924100916, "ENBREL": 0.6126143487194265, "ESMYA": 6.707144644639451, "EVRA": 2.8882909445655454, "FAMPYRA": 1.5950308564565785, "FASLODEX": 0.6675162226783142, "GARDASIL": 1.900190200592024, "HUMIRA": 0.3703333486520281, "IBRANCE": 0.4996513651234544, "IBUPROFEN": 0.5480962530554115, "INCIVO": 3.250206722718535, "KAFTRIO": 6.107319551790427, "KEPPRA": 8.013237491112273, "LANTUS": 0.12221570874443, "LATUDA": 6.207860266090219, "LEVETIRACETAM": 3.505062928250133, "LYRICA": 0.915665872498556, "MEPOLIZUMAB": 0.5884841139772296, "NUCALA": 1.3751248099951157, "OLANZAPINE": 0.5982422448584888, "ORKAMBI": 3.379896707076513, "PEGASYS": 3.773605450971736, "PEGINTERFERON": 1.6086572127665886, "PEGINTRON": 3.3228463373999326, "PLEGRIDY": 1.3460587849910317, "RIBAVIRIN": 1.1014466963652907, "RINVOQ": 0.5682555516948893, "RISPERIDONE": 3.8223233951197466, "RYEQO": 15.989526844285349, "SAXENDA": 0.6141265894305459, "SOVALDI": 2.400183233757752, "SPIKEVAX": 0.3231366915541914, "STELARA": 0.272736086432313, "SUBOXONE": 0.8742767341278815, "SUTENT": 0.1017615747405311, "TAMIFLU": 1.3037144133630654, "TOZINAMERAN": 0.5625674376185241, "TRULICITY": 0.4823486655194327, "TRUVADA": 0.1410920379665391, "VARENICLINE": 15.749139610367603, "VAXZEVRIA": 0.1920078855141808, "VIMPAT": 2.494658604364797, "XELJANZ": 0.2567036842161765, "XOLAIR": 0.4140579618641022, "XTANDI": 0.3350258537200689, "ZYPREXA": 0.976837638866148, "null": 1.4588185312724875}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7729.json
index 312f47fa3bf..1cfd6e92a25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7729.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7729.json
@@ -1 +1 @@
-{"ATRIPLA": 31.003153552017856}
\ No newline at end of file
+{"AMIKACIN": 234.4438383409893, "null": 0.3111599477039508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/773.json
index 33d9609e702..a7568af7090 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/773.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/773.json
@@ -1 +1 @@
-{"IPILIMUMAB": 190.2043671983852, "KEYTRUDA": 31.257978707578943, "OPDIVO": 37.69317824285383, "PEMBROLIZUMAB": 77.26029267063099}
\ No newline at end of file
+{"COMIRNATY": 0.3827640022336913, "GARDASIL": 4.818781612933058, "MMRVAXPRO": 20.75810856637325, "VAXZEVRIA": 1.8261832826070177, "null": 1.649221761068391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7730.json
index bc8910b3cff..d8e2f979835 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7730.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7730.json
@@ -1 +1 @@
-{"ABATACEPT": 3.818274494303122, "ADALIMUMAB": 1.3869872919860189, "AMINOSALICYLIC": 16.471506387492404, "ATRIPLA": 1.087930428281957, "CIMZIA": 2.085194695992464, "COSENTYX": 13.98240758343183, "ELIQUIS": 1.1068280530643793, "ENTYVIO": 11.33880390193463, "HUMIRA": 6.5385834498678665, "PEGASYS": 2.3040922480987542, "SIMPONI": 12.143500630473383, "STELARA": 3.772376487167362, "TOZINAMERAN": 1.0970931628012055, "XELJANZ": 3.2989709352108663, "ZOSTAVAX": 2.6045687497375662}
\ No newline at end of file
+{"CHAMPIX": 25.744439973842464, "CYMBALTA": 2.774525712990896, "KEPPRA": 8.47075235077395, "null": 2.232492002057343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7731.json
index 651a50a3c02..28121f4aaa0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7731.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7731.json
@@ -1 +1 @@
-{"ADALIMUMAB": 10.83815548455303, "ANAKINRA": 116.03042657379598, "COSENTYX": 8.460794831368258}
\ No newline at end of file
+{"null": 4.139418728484751}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7732.json
index 9e63a895f40..c301ac4fbc9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7732.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7732.json
@@ -1 +1 @@
-{"ATRIPLA": 12.804722585507765, "STRIBILD": 11.455756623183191, "ZOSTAVAX": 7.257123795243408}
\ No newline at end of file
+{"BORTEZOMIB": 284.2395129934279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7733.json
index 44d2ba5fa9a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7733.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7733.json
@@ -1 +1 @@
-{"ATRIPLA": 13.641233563602716}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7734.json
index 554681b665d..bb0e5cce377 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7734.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7734.json
@@ -1 +1 @@
-{"EPCLUSA": 72.47677420815941, "INCIVO": 42.50509988842207, "NEXAVAR": 11.543509920376112, "PEGASYS": 19.099931836037594, "PEGINTERFERON": 21.26076367312149, "PEGINTRON": 10.715034833200743, "RIBAVIRIN": 21.08094225289485, "SOVALDI": 47.82313725936973}
\ No newline at end of file
+{"BUPRENORPHINE": 18.20448632823347, "COMIRNATY": 0.2954226116961483, "LANTUS": 4.977319337492919, "SPIKEVAX": 0.3912202061260723, "TOZINAMERAN": 2.3419274388004854, "VAXZEVRIA": 1.261303416431446, "null": 0.5663816245050736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7735.json
index 9deef985af7..4595396f500 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7735.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7735.json
@@ -1 +1 @@
-{"null": 1.5239202029864345}
\ No newline at end of file
+{"null": 2.8614231857080017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7736.json
index 3097d9d1b6d..2100cd53f51 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7736.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7736.json
@@ -1 +1 @@
-{"BRILIQUE": 17.18859803198686, "CLOPIDOGREL": 7.050913568777228, "COMIRNATY": 1.3299776183972618, "ELIQUIS": 7.958096271270964, "ENOXAPARIN": 8.301848461482928, "PLAVIX": 5.386888734547451, "VAXZEVRIA": 1.8719117892174368, "null": 1.35200509860466}
\ No newline at end of file
+{"ARAVA": 2.966482432602408, "COMIRNATY": 1.1217999504713343, "VAXZEVRIA": 0.3441934777504871, "null": 0.3569637115006725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7737.json
index 9edd5dbdb96..411e21913c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7737.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7737.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 8.399404948862976, "ELIQUIS": 17.844688464183093, "HEMLIBRA": 180.42468064031465, "null": 1.2417289382201258}
\ No newline at end of file
+{"METHOTREXATE": 66.34791428288914, "null": 0.4958355647992369}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7738.json
index a6ed16513c2..bea38940ec1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7738.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7738.json
@@ -1 +1 @@
-{"VIAGRA": 112.22790155085262, "null": 1.2088494337393478}
\ No newline at end of file
+{"BRINTELLIX": 5.254104222801221, "COMIRNATY": 0.8063387296542416, "CYMBALTA": 2.0719476996798294, "GARDASIL": 4.564294642739241, "PEGASYS": 1.65950283295348, "SPIKEVAX": 0.7445633913598015, "TOZINAMERAN": 4.744782369899864, "VAXZEVRIA": 2.014066865782056, "null": 0.6189488903609283}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7739.json
index 0b11f69456b..0b98429338f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7739.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7739.json
@@ -1 +1 @@
-{"null": 1.0375289796092422}
\ No newline at end of file
+{"ASPARAGINASE": 65.92066238831329, "AVAMYS": 16.649056338617424, "INFANRIX": 65.78443483083953, "KEPPRA": 6.632552171160513, "null": 3.26068865466018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/774.json
index f74e10d1a04..9e593b5d67c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/774.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/774.json
@@ -1 +1 @@
-{"GARDASIL": 15.68810972734583}
\ No newline at end of file
+{"ABATACEPT": 6.022164447106668, "ADALIMUMAB": 12.928797803749005, "ANAKINRA": 50.79758454212926, "ARANESP": 12.93139075192816, "ARAVA": 0.9239955344694648, "COMIRNATY": 0.1698258839875879, "NOVOSEVEN": 52.64303882449443, "NPLATE": 20.66925026279972, "null": 0.5659335359266228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7740.json
index 7848a97ad9d..470effc05cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7740.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7740.json
@@ -1 +1 @@
-{"STEROIDS": 16.07254395745642, "null": 172.7288228115046}
\ No newline at end of file
+{"ABILIFY": 1.8364647643906649, "ALISKIREN": 50.08489984154525, "ARAVA": 0.5932918719234697, "ASPARAGINASE": 2.0277978531552314, "ATRIPLA": 0.091357062927142, "AUBAGIO": 2.0872173526915976, "BUPIVACAINE": 11.143360523149653, "CARBIDOPA": 11.047993551196289, "CELLCEPT": 1.0968520446704773, "CHAMPIX": 0.5841309369287021, "CICLOSPORIN": 0.4634373889108254, "CLOPIDOGREL": 0.8161774299352901, "COMIRNATY": 0.8837116188869785, "COSENTYX": 1.0620144985022983, "CYMBALTA": 0.4590114411990622, "ELIQUIS": 0.2962942361931437, "ENBREL": 0.8516182003952846, "ENTACAPONE": 29.35575909122322, "ESOMEPRAZOLE": 4.9337685733766605, "FAMPYRA": 29.07872692211426, "FENTANYL": 1.2527657933282608, "FIRDAPSE": 3.8288868154505455, "GARDASIL": 1.8916955005770093, "HUMALOG": 0.4087583170367179, "IBUPROFEN": 1.221128477258644, "KEPPRA": 0.8031176941745893, "KEYTRUDA": 0.4518701315168428, "LANTUS": 0.3046047432914416, "LEMTRADA": 2.3003001074795377, "LEVETIRACETAM": 3.2781991690739973, "LEVODOPA": 10.732357297884976, "OLANZAPINE": 1.1880206845602042, "OPTIMARK": 8.128637198305313, "PEGASYS": 0.345837200842376, "PLAVIX": 0.4849159324111979, "PLEGRIDY": 6.742709486838122, "SHINGRIX": 1.0280303680542022, "SIFROL": 4.883028722099444, "SPIKEVAX": 0.5538542079298633, "SPINRAZA": 19.01756437435784, "SPIRONOLACTONE": 9.757556232852007, "STALEVO": 5.006339917569944, "TASIGNA": 1.6086855623797176, "TOZINAMERAN": 0.6309240922792182, "TWINRIX": 2.4558099113729592, "VAXZEVRIA": 0.4458123899241924, "XOLAIR": 0.9228460494107656, "XTANDI": 0.991011793458921, "ZYPREXA": 0.8303601036293305, "null": 1.2427023604208196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7741.json
index fade82264ca..105e1828eb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7741.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7741.json
@@ -1 +1 @@
-{"MEPOLIZUMAB": 33.3962747168102, "NUCALA": 8.203618624413462, "PEGASYS": 2.8273863177485663, "null": 1.2433768299228525}
\ No newline at end of file
+{"COMIRNATY": 0.8621605217230238, "RILUTEK": 1354.1392518161315, "SPIKEVAX": 0.4936991488150536, "TOZINAMERAN": 2.068285614756848, "VAXZEVRIA": 0.7156971442756519, "null": 0.404765666355987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7742.json
index c8600ceacbd..37712115836 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7742.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7742.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 46.333141196941135, "BEDAQUILINE": 93.69305410831306, "BUDESONIDE": 62.3514180663762, "MEPOLIZUMAB": 33.17711366969584}
\ No newline at end of file
+{"COMIRNATY": 0.4366713026788487, "null": 1.6810340723503845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7743.json
index 999c00fa98f..9de57ea8489 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7743.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7743.json
@@ -1 +1 @@
-{"ACLIDINIUM": 25.707633823946264, "AVAMYS": 30.49434085564466, "BENLYSTA": 1.6347279390279974, "BENRALIZUMAB": 127.26802953674256, "BUDESONIDE": 10.178126069238433, "COMTAN": 6.939904049131369, "COSENTYX": 2.168630957434489, "DUAKLIR": 162.67305660692028, "ESBRIET": 2.458611805945425, "FLUTICASONE": 28.53213473183722, "GLYCOPYRRONIUM": 81.47849535863254, "HIZENTRA": 4.471242491455896, "INCRUSE": 13.311410504466622, "IRON": 17.550379024374468, "MEPOLIZUMAB": 73.55891724973631, "METHOTREXATE": 1.2755950832374456, "NUCALA": 26.611245096240008, "OFEV": 2.947600543336244, "OMALIZUMAB": 52.83208032032173, "OPSUMIT": 2.924145794291975, "RELVAR": 11.523325737033844, "TRELEGY": 4.376865578213933, "UMECLIDINIUM": 24.47563114611425, "XELJANZ": 1.8387027588194755, "XOLAIR": 16.468371354490174}
\ No newline at end of file
+{"VAXZEVRIA": 3.012217559750209, "null": 0.4656970531888171}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7744.json
index 6d6bac27fa9..3e3d5176d8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7744.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7744.json
@@ -1 +1 @@
-{"BUDESONIDE": 3.248305317497433, "INCRUSE": 18.44765925060612, "KAFTRIO": 63.803963797173466, "MEPOLIZUMAB": 35.13072486842116, "ORKAMBI": 47.25802614294438, "RELVAR": 14.938655172918264, "TRELEGY": 9.00064728229549, "XOLAIR": 2.3035979674062435, "null": 1.5280636966727796}
\ No newline at end of file
+{"ADVATE": 34.60356212098903, "AFINITOR": 1.0882218426044576, "ALISKIREN": 10.808226262775586, "APIXABAN": 2.9182167870477342, "ARAVA": 0.3023030081234864, "AVASTIN": 1.6215798146611111, "BRILIQUE": 2.847273622023609, "CHAMPIX": 0.6546319925907589, "CLOPIDOGREL": 6.019550413085313, "COMIRNATY": 0.3233242535351445, "CYMBALTA": 0.367089981914414, "CYTARABINE": 1.2412548160470522, "DEFITELIO": 26.962058141958032, "ELIQUIS": 7.588639733348835, "ENOXAPARIN": 4.823493371573161, "EXJADE": 1.07375721962602, "FENTANYL": 1.356132014781865, "GARDASIL": 0.6442947352748559, "HEMLIBRA": 45.31209499041631, "IBRANCE": 0.5312353354060073, "IBUPROFEN": 1.222955345938194, "KEPPRA": 0.681509737443545, "KEYTRUDA": 0.3637088792693014, "LIXIANA": 15.50421722005541, "NEXAVAR": 3.678798995538519, "NPLATE": 14.5808009714183, "PEGASYS": 1.860619294592303, "PEGINTRON": 1.381623748365982, "PLAVIX": 8.649762311659893, "SPIKEVAX": 0.3166179782294892, "STIVARGA": 1.8732821183274937, "SUTENT": 4.486228697797762, "TOZINAMERAN": 0.4282968448872058, "VAXZEVRIA": 0.5169059779507968, "XARELTO": 10.192896405835326, "null": 1.1902063686907896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7745.json
index ea776cecd9f..8c10179baca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7745.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7745.json
@@ -1 +1 @@
-{"ACLIDINIUM": 167.39246541651318, "LEVOFLOXACIN": 12.080150604444048, "MEPOLIZUMAB": 52.82226378092133, "NUCALA": 16.456441624276096, "null": 1.1703034410162714}
\ No newline at end of file
+{"COMIRNATY": 0.1129143448334181, "EFAVIRENZ": 28.339872014752263, "GARDASIL": 2.559722159869604, "PEGASYS": 2.0821070060505384, "SUTENT": 43.574005011678125, "VAXZEVRIA": 0.1500056148186596, "null": 1.146744287097768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7746.json
index 43bb7805508..f4673e00ccf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7746.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7746.json
@@ -1 +1 @@
-{"ADCIRCA": 49.06237616204141, "NUCALA": 21.661509990296125, "XOLAIR": 4.97966480795533, "null": 1.468398589943359}
\ No newline at end of file
+{"AFINITOR": 1.5812076409619336, "BETMIGA": 3.7193403503664033, "BUDESONIDE": 0.6595943662862911, "CHAMPIX": 2.3675601942732225, "CLOPIDOGREL": 0.654309198974941, "COMIRNATY": 0.5576847721993654, "DEXAMETHASONE": 0.6496900972486543, "ELIQUIS": 0.5286780152741614, "ENTRESTO": 1.4988116370219915, "IBRANCE": 0.6163882054104616, "IMATINIB": 7.206097518885825, "JARDIANCE": 0.391656229035982, "LANTUS": 0.5361247034904125, "MMRVAXPRO": 0.7199869979054501, "NEXAVAR": 1.2415791757695802, "NUCALA": 0.6278624876508834, "PEGASYS": 0.6297474260100763, "SPIKEVAX": 0.4929128616203226, "SUTENT": 1.0716177308029722, "TASIGNA": 1.096077453158236, "TOVIAZ": 3.290525796172336, "TOZINAMERAN": 1.2213667528987493, "VAXZEVRIA": 0.4744391424563351, "XOLAIR": 2.278699143611436, "null": 3.48528850387764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7747.json
index 2aa6a7d18e3..7c5c73137c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7747.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7747.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 2.644768195570089, "BIKTARVY": 3.2673801541628475, "BRAFTOVI": 4.804410649424433, "CELLCEPT": 12.475674599889643, "CIALIS": 154.86879200899787, "CICLOSPORIN": 17.027931354295355, "CIMZIA": 1.7494766052407982, "COSENTYX": 2.151391849814364, "DEXAMETHASONE": 1.0316923328782868, "GLIVEC": 7.430656658134777, "HUMIRA": 3.144724524155957, "JAKAVI": 38.301935310868586, "MEKINIST": 4.031246219712018, "METHOTREXATE": 3.1516098519335283, "MYCOPHENOLATE": 5.615078138353351, "NEXAVAR": 3.585907864689541, "REMICADE": 7.212812928915743, "RINVOQ": 2.952690517913461, "RITUXIMAB": 2.21085086764347, "ROACTEMRA": 2.429158696009776, "RUXOLITINIB": 60.1541555209201, "SIMPONI": 1.970417888624432, "STELARA": 13.270028462710686, "VEMURAFENIB": 148.64567988873424, "VFEND": 12.31691794009347, "VIAGRA": 2.186302000294299, "VORICONAZOLE": 28.479407296174777, "XELJANZ": 2.99282341411217, "XOLAIR": 1.9011824095179244, "ZELBORAF": 113.2547770819626}
\ No newline at end of file
+{"ABACAVIR": 0.2670086956487811, "ABRAXANE": 9.370436500008594, "ADALIMUMAB": 0.1193632749385453, "AFINITOR": 7.060464537761432, "AIMOVIG": 0.7214057093236317, "ALIMTA": 1.124192615691427, "AMINOSALICYLIC": 0.7183490721343706, "ANAKINRA": 0.8437699786553877, "ANORO": 1.259250314506287, "APIXABAN": 0.4255145746426338, "ARANESP": 0.4198353344154634, "ARAVA": 1.4794673905689797, "ATEZOLIZUMAB": 8.218892046920114, "AUBAGIO": 0.6162611901367044, "AVASTIN": 1.4276124544087605, "BEDAQUILINE": 1.289322560040355, "BENLYSTA": 1.1519866085919603, "BEVACIZUMAB": 2.3388730944142164, "BUDESONIDE": 0.2238700146352598, "BUSULFAN": 3.9268241375556343, "BYDUREON": 0.454677236727022, "CAELYX": 2.9870909385078663, "CAPECITABINE": 1.279201171400162, "CELLCEPT": 2.332845433051597, "CHAMPIX": 2.5022053444566943, "CICLOSPORIN": 2.440214246700545, "CIMZIA": 2.040017542687915, "CLOPIDOGREL": 0.9384663680352934, "COAPROVEL": 1.7982723986432458, "COMBIVIR": 1.1597910513168577, "COMIRNATY": 0.2567816476680118, "COSENTYX": 3.6839649164312216, "CYMBALTA": 0.3564692744558854, "CYTARABINE": 1.220107820891114, "DEXAMETHASONE": 1.5958231194123855, "DOCETAXEL": 2.1569063492458667, "DOXORUBICIN": 1.992755737370992, "ELIQUIS": 0.1580709138559846, "ENBREL": 0.8104523954563461, "ENTYVIO": 3.5550785548762205, "ETANERCEPT": 5.906053951647388, "EVEROLIMUS": 5.01274661406502, "EXJADE": 1.1109954334278842, "FASLODEX": 1.3327103229025417, "FILGRASTIM": 4.5161053343012325, "FULVESTRANT": 1.2417286049451235, "GARDASIL": 0.74866885223869, "HALAVEN": 3.0329397701465703, "HERCEPTIN": 1.0966897820791564, "HUMIRA": 2.1291104031022425, "IBRANCE": 1.892416436800064, "IBUPROFEN": 1.0144987948512152, "IMATINIB": 2.9768505782505854, "INCIVO": 1.9792497885773088, "INFLIXIMAB": 4.513483320089829, "INLYTA": 1.8055317482253657, "IRESSA": 2.9457374622225267, "JAKAVI": 1.3276228584535434, "KEPPRA": 0.3897443534203945, "KEYTRUDA": 0.4691046360109314, "LAMIVUDINE": 2.092034122131244, "LENVIMA": 1.4227831079737203, "LEVOFLOXACIN": 1.581020017892636, "MABTHERA": 1.748986632820439, "MERCAPTOPURINE": 3.622239048221112, "METHOTREXATE": 5.722383940215079, "MYCOPHENOLATE": 1.5220617833974055, "NEULASTA": 0.9372493115490822, "NEXAVAR": 2.2890906393397765, "NIMENRIX": 0.8430416028320616, "NUCALA": 0.3286679198144018, "OCRELIZUMAB": 1.3506075076646638, "OLANZAPINE": 0.3701822379371811, "PEGASYS": 1.6619896998429762, "PEGINTERFERON": 3.348314523951591, "PEGINTRON": 1.6362857642195507, "PEMBROLIZUMAB": 1.510897679099935, "PEMETREXED": 2.584181272144885, "PLAVIX": 0.5011897644181994, "PROTELOS": 9.7200562044117, "RAPAMUNE": 7.696760851376101, "RELVAR": 1.803754502592912, "RINVOQ": 2.026595379879625, "RITUXIMAB": 0.7948681383233478, "ROACTEMRA": 4.2701979709081535, "SIMPONI": 0.8290720495108599, "SPIKEVAX": 0.2523617846163138, "STELARA": 0.8367849590000158, "STIVARGA": 3.5164763401527064, "SUTENT": 7.904815489243746, "TAGRISSO": 2.0692533413201595, "TAMIFLU": 1.8042129644218083, "TOZINAMERAN": 1.251134038937647, "TRELEGY": 2.3961128021309275, "VAXZEVRIA": 0.7837844116119814, "VIRAMUNE": 5.449754130300336, "VOTRIENT": 0.474794895146964, "XELJANZ": 1.579300034460373, "XELODA": 2.1701152747591235, "XOLAIR": 0.8473550517866064, "ZOSTAVAX": 0.3024761722057787, "null": 1.0234208852197215}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7748.json
index d1c76e657c0..b549ada2f63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7748.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7748.json
@@ -1 +1 @@
-{"null": 1.0959544438155733}
\ No newline at end of file
+{"ABASAGLAR": 1.8389941774940357, "ABATACEPT": 0.1894227649508564, "ABILIFY": 0.8894862227558716, "AFINITOR": 0.733106079591655, "AIMOVIG": 0.4407532793152914, "ANAKINRA": 0.6227407598668895, "APIDRA": 0.6135772513689269, "ARAVA": 0.2612534616239832, "ARIPIPRAZOLE": 1.2164243943554396, "ATRIPLA": 0.0980468210343717, "AUBAGIO": 3.123824406102803, "AVAMYS": 2.194796834336664, "AVANDIA": 0.4276913662917296, "AVASTIN": 0.6374796402193575, "AZILECT": 3.906124373508813, "BENLYSTA": 1.7650373531175512, "BENZODIAZEPINES": 13.086613918213608, "BONVIVA": 3.7582723028538094, "BRIDION": 2.1267923279316525, "BRINTELLIX": 0.3720797981937027, "BUPIVACAINE": 2.2992936963776933, "CARBIDOPA": 3.959015891206772, "CELECOXIB": 1.03841929613136, "CELLCEPT": 0.5011057429818665, "CHAMPIX": 0.4020587622227223, "CICLOSPORIN": 0.2204853892630117, "CIMZIA": 0.704477889631232, "CLOPIDOGREL": 0.3123929027474734, "COMIRNATY": 1.3317373890657227, "COMTAN": 4.792740523184088, "COSENTYX": 1.8770177014937857, "CYMBALTA": 1.2882084925164303, "DEXAMETHASONE": 0.2216585318222132, "ELIQUIS": 0.4860821578519217, "ENBREL": 0.2054821828409485, "ENTACAPONE": 3.3393979533287625, "ENTRESTO": 0.8169592015973842, "EVISTA": 1.01670204985307, "EXFORGE": 2.1215067836212778, "EXJADE": 0.3100512633144247, "FAMPYRA": 0.6986972859214726, "FASENRA": 0.622579390059646, "FASLODEX": 0.6795212861569631, "FENTANYL": 1.4709318264781988, "FIRDAPSE": 1.2122827091873905, "FORSTEO": 1.1245557367757189, "FULVESTRANT": 1.360919141291269, "GARDASIL": 1.9105856466647737, "GILENYA": 7.327885998189389, "HEPSERA": 2.1368420258205894, "HUMALOG": 0.8548602900181913, "HUMIRA": 0.4972316559402814, "IBRANCE": 0.7970977848064679, "IBUPROFEN": 0.6577988661961662, "IMATINIB": 2.7834182933234723, "INFANRIX": 3.71586303580453, "INLYTA": 0.8745781217358737, "JANUMET": 0.7548533697431253, "JANUVIA": 0.3374810833007909, "JARDIANCE": 0.1513189351409599, "KEPPRA": 0.7990744323993977, "KEYTRUDA": 1.0345879338781672, "LACOSAMIDE": 1.5464946947252154, "LANTUS": 0.7919909402090513, "LATUDA": 1.7371394813224137, "LEVETIRACETAM": 0.485352265078649, "LEVODOPA": 7.844531657826774, "LEVOFLOXACIN": 0.407267879732338, "LYRICA": 1.0034932961871503, "MEKINIST": 0.5169405879050226, "METHOTREXATE": 0.5230266197500398, "MIDAZOLAM": 3.279379380682679, "MMRVAXPRO": 0.6571214059625138, "NEXAVAR": 0.1683978970027087, "NUCALA": 0.4421446814621497, "OCRELIZUMAB": 0.5927710589974949, "OLANZAPINE": 0.9129009023764209, "OPDIVO": 0.9611708706438165, "OPSUMIT": 0.2244482985904206, "OPTIMARK": 16.99093514477029, "PEGASYS": 0.0834455004540823, "PEGINTRON": 0.3751670057190212, "PLAVIX": 0.3901908793921254, "RISPERIDONE": 2.581078911780785, "RITUXIMAB": 0.8373346517645395, "ROACTEMRA": 0.3835495858365307, "SHINGRIX": 1.75709452632787, "SIFROL": 1.7508250875121594, "SIMPONI": 0.2735740211090972, "SPIKEVAX": 0.952584651641495, "STALEVO": 5.751234979080472, "STELARA": 0.1599588028787531, "SUBOXONE": 0.23316878927652, "SUTENT": 0.7492211231955407, "TAMIFLU": 0.5953334546698476, "TASIGNA": 0.6287659418349508, "TOVIAZ": 0.7891365452446962, "TOZINAMERAN": 2.053709617537133, "TRELEGY": 0.4194073175627958, "TRUVADA": 0.1303592999070267, "TWINRIX": 3.303751596059743, "VAXZEVRIA": 0.5945831242639726, "VIAGRA": 1.0335017471214354, "VIMPAT": 0.9361081421795856, "VOTRIENT": 0.426407090087762, "XELJANZ": 1.962590722313517, "XOLAIR": 1.020405117271491, "XTANDI": 0.7277844832373845, "ZOSTAVAX": 0.7944112013710668, "ZYPADHERA": 1.8711534936313945, "ZYPREXA": 0.7557683957628305, "null": 1.1198689764817569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7749.json
index 6d892dee932..124ecb70d48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7749.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7749.json
@@ -1 +1 @@
-{"STELARA": 11.694967648116554}
\ No newline at end of file
+{"ICLUSIG": 138.05836805067898, "null": 0.3739339492136918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/775.json
index 5d25aadd35c..b26881f3f77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/775.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/775.json
@@ -1 +1 @@
-{"IPILIMUMAB": 64.7715477480444, "KEYTRUDA": 37.87823796219618, "OPDIVO": 41.17946796875452}
\ No newline at end of file
+{"COMIRNATY": 7.300215894772826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7750.json
index 0a69e7f7107..1c93d877847 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7750.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7750.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 15.960631102842264, "CELLCEPT": 15.513792599854716, "CICLOSPORIN": 13.3252864784407, "COSENTYX": 1.3216098862916108, "ENTYVIO": 2.6697079505450554, "HUMIRA": 2.5019819602299544, "JAKAVI": 30.801730150549943, "KEYTRUDA": 1.6377428506272944, "LIBTAYO": 71.47440420971948, "MEKINIST": 4.642306902251658, "MYCOPHENOLATE": 32.02257602776981, "NEXAVAR": 8.954914664525031, "REVLIMID": 15.7859665285922, "RINVOQ": 6.275978905977544, "RUXOLITINIB": 55.94068966087306, "SIMPONI": 1.3075724537415436, "SORAFENIB": 28.353003645537928, "STELARA": 5.230397285948582, "TACROLIMUS": 21.68212317763691, "TREMFYA": 5.696122482542955, "VEMURAFENIB": 116.26438322960816, "VFEND": 34.13045195402731, "VORICONAZOLE": 95.47253107069452, "XELJANZ": 2.87892501999679, "ZELBORAF": 69.61553247999973, "ZOSTAVAX": 1.6458723305269167}
\ No newline at end of file
+{"null": 1.174616373878293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7751.json
index c4ae59de8f5..5964ec2bdf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7751.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7751.json
@@ -1 +1 @@
-{"CICLOSPORIN": 15.540744090947078, "METHOTREXATE": 24.36838048705268}
\ No newline at end of file
+{"EVISTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7752.json
index 68f68f4339a..95d54906558 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7752.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7752.json
@@ -1 +1 @@
-{"CICLOSPORIN": 14.176702104609326}
\ No newline at end of file
+{"null": 0.6110021031734242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7753.json
index 1383c4b9598..472340840a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7753.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7753.json
@@ -1 +1 @@
-{"null": 1.5606479191974876}
\ No newline at end of file
+{"null": 0.8277566403541591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7754.json
index e2998e36555..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7754.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7754.json
@@ -1 +1 @@
-{"null": 1.609848241428752}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7755.json
index 8debce24972..6ca7327a99f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7755.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7755.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 25.222769160984303, "ASPARAGINASE": 16.095596665461926, "AZACITIDINE": 21.238791734885112, "BORTEZOMIB": 55.40116470785328, "BUSULFAN": 13.39856314880448, "CELLCEPT": 3.0281214940116405, "CICLOSPORIN": 6.536825229733476, "CUBICIN": 139.58746271416047, "CYTARABINE": 12.256940557521672, "DAPTOMYCIN": 164.40288221150644, "DEXAMETHASONE": 5.937573221561912, "DOXORUBICIN": 15.23226271758612, "FILGRASTIM": 43.407933374971314, "METHOTREXATE": 3.0242383000642485, "MYCOPHENOLATE": 9.481240695555716, "OPSUMIT": 1.8924502762018007, "PEGASYS": 1.7809135187312233, "PEGINTERFERON": 5.882792861410981, "RITUXIMAB": 4.137839760243665, "SOLIRIS": 5.9768115884475455, "STELARA": 2.2548680041100884}
\ No newline at end of file
+{"CICLOSPORIN": 157.4498373651491}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7756.json
index f9d50aef15c..c7cd121c02a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7756.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7756.json
@@ -1 +1 @@
-{"ABILIFY": 7.904162504974314, "ABRAXANE": 5.857026410008794, "ALEMTUZUMAB": 4.960666192034022, "AMIKACIN": 3.1385542133827, "ARANESP": 1.292740108296961, "ASPARAGINASE": 6.086755783066449, "ATAZANAVIR": 1.729903798716572, "AUBAGIO": 1.2339929773780096, "AVONEX": 23.59299833629277, "AZATHIOPRINE": 1.9645359403938285, "AZTREONAM": 11.905407732441558, "BASILIXIMAB": 4.604278733726862, "BENLYSTA": 3.388710284263295, "BIKTARVY": 1.6410624829885638, "BLINCYTO": 15.104143227457088, "BORTEZOMIB": 3.462095060056636, "BRIVIACT": 2.374634012613188, "BUSILVEX": 8.324231707801951, "BUSULFAN": 6.017526315367524, "CANAKINUMAB": 46.722405571583664, "CANCIDAS": 2.243105678053489, "CARMUSTINE": 3.13841633132439, "CEFTAROLINE": 101.24909970862343, "CELLCEPT": 3.069252521466123, "CICATRIZANTS": 177.1807280797498, "CICLOSPORIN": 5.188843893456624, "CIMZIA": 2.5447318845239675, "CINRYZE": 6.843836990133736, "COSENTYX": 3.353025914641464, "CUBICIN": 18.17486335122408, "CYTARABINE": 4.552520600362821, "DAPTOMYCIN": 39.31743736502168, "DEXAMETHASONE": 2.4063704825053667, "ENBREL": 1.886178666310721, "ENTRESTO": 1.0723085910776635, "EXJADE": 3.2893348568598206, "FAMPRIDINE": 17.74879486115874, "FILGRASTIM": 2.398277542913114, "FULVESTRANT": 2.4473078309516287, "GANCICLOVIR": 3.48373986014909, "HIZENTRA": 9.890603931125645, "HUMALOG": 2.305646006901139, "HUMAN": 1.8462329910033752, "HUMIRA": 1.4171252256282505, "HYDROCORTISONE": 2.064096075479869, "INCRUSE": 2.921068007709645, "INSULIN": 1.4757523795637824, "KALETRA": 1.9526686402011288, "KYMRIAH": 1.5632541608874593, "LANTUS": 2.2280380165844624, "LEMTRADA": 1.0563607105395232, "LEVEMIR": 2.172171688203573, "LEVOFLOXACIN": 1.4378627990682904, "LYRICA": 1.7731328737991927, "MELATONIN": 2.246636484554279, "MELPHALAN": 4.4873874708435535, "METHOTREXATE": 2.679610827127905, "MYCOPHENOLATE": 5.953067724101575, "NEULASTA": 1.1089814796490267, "NOT": 1.828414812115839, "NPLATE": 1.1113594684445594, "OPSUMIT": 2.5910246966929185, "ORKAMBI": 12.543138387665088, "PEGASYS": 3.1196453740335053, "PEGINTERFERON": 1.7446160518601217, "PEGINTRON": 2.660549738248412, "PRIVIGEN": 3.5151275950197425, "REMICADE": 6.733513779723356, "REVATIO": 1.5301820088444151, "REVLIMID": 2.1861837003579865, "RINVOQ": 1.31343548342814, "RITUXIMAB": 1.4982373365787232, "ROACTEMRA": 1.9793851116750016, "RUCONEST": 4.8779349148566284, "SIMPONI": 2.1336418583935104, "SOLIRIS": 4.152381685386734, "STELARA": 4.69020892587279, "SUBOXONE": 1.988354794347624, "SYNAGIS": 2.301063998896947, "TACROLIMUS": 3.4611760965196705, "TAMIFLU": 1.4100440753495238, "TOBRAMYCIN": 6.208773911674653, "TOCILIZUMAB": 3.912014760890768, "TRACLEER": 2.826765265686747, "TREMFYA": 2.6621656295759712, "VFEND": 1.137857825798746, "XELJANZ": 3.131550994475061, "XOLAIR": 1.1768945864065046, "null": 1.1693249395507144}
\ No newline at end of file
+{"null": 1.223520181574243}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7757.json
index e1bfef782ef..f40da4d0f0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7757.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7757.json
@@ -1 +1 @@
-{"CICATRIZANTS": 13749.967313847352, "null": 1.375986247019643}
\ No newline at end of file
+{"null": 0.8356890691444494}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7758.json
index d1799bc2e7a..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7758.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7758.json
@@ -1 +1 @@
-{"ALIMTA": 4.528023227796149, "AMIKACIN": 9.81378396551248, "AZACITIDINE": 16.212030770111898, "BORTEZOMIB": 19.992138842365183, "BUDESONIDE": 2.7257276833259088, "BUSULFAN": 13.735725712470389, "CANCIDAS": 12.7876201157994, "CELLCEPT": 3.0082401415634226, "CICLOSPORIN": 6.235923952087454, "CIMZIA": 1.4244397519344167, "CUBICIN": 8.457407179613572, "CYTARABINE": 9.32876394480068, "DARZALEX": 7.603985347213098, "DEXAMETHASONE": 2.2084225157174915, "EXJADE": 1.9983335085356373, "IBUPROFEN": 2.5557077354332383, "INCIVO": 15.72155269759164, "LEVOFLOXACIN": 2.4402485822393976, "METHOTREXATE": 4.963234142527649, "OPTIMARK": 2.573547081837788, "PEGASYS": 3.9824985413981504, "PEGINTERFERON": 4.902448837393527, "PEGINTRON": 1.6969093283072534, "RITUXIMAB": 4.76105818679071, "ROACTEMRA": 11.305697959882789, "SOLIRIS": 10.176987260901477, "STELARA": 1.1151404422542426, "TAMIFLU": 4.904903271744077, "TRACLEER": 2.4191864465016697}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7759.json
index afb25a8bd74..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7759.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7759.json
@@ -1 +1 @@
-{"COSENTYX": 8.742535551625716, "PEGASYS": 7.225551169262287}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/776.json
index d0024ff4eaf..41720568c7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/776.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/776.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0419797819288057, "LEMTRADA": 128.67900246225378}
\ No newline at end of file
+{"ARIPIPRAZOLE": 12.20158153020344, "FENTANYL": 8.214169926683484, "MIDAZOLAM": 19.59069455224311, "OLANZAPINE": 65.76329751970309, "OXYBUTYNIN": 54.25472618169631, "TOVIAZ": 14.658867231176783, "ZYPREXA": 4.0707804444432965, "null": 2.6019068864778494}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7760.json
index d0176ddcfb0..334e882d3db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7760.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7760.json
@@ -1 +1 @@
-{"COSENTYX": 2.7300292250070206, "CUBICIN": 22.673527040134186, "CYTARABINE": 6.9257335106474125, "ERBITUX": 64.7901255537391, "EYLEA": 13.1720995027904, "FYCOMPA": 30.773475985095885, "KEPPRA": 2.7917286286653487, "OMALIZUMAB": 21.07837394453258, "OPSUMIT": 8.821875751609378, "null": 1.1872246086420872}
\ No newline at end of file
+{"CELLCEPT": 249.72740261789332}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7761.json
index c1c20c12ccb..8b47c3733f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7761.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7761.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 3.8802920195878094, "CYMBALTA": 2.357840608975428, "GARDASIL": 6.79695711062048, "INFANRIX": 25.64488051212008, "KEPPRA": 7.0045545483767615, "LACOSAMIDE": 9.848477393531736, "LANTUS": 1.0734430862279063, "LEVETIRACETAM": 4.781824550238014, "MMRVAXPRO": 9.926845169763938, "NIMENRIX": 11.444135577137825, "PEGINTRON": 2.589372448623031, "PREVENAR": 17.586787577628197, "TAMIFLU": 3.7913434651412032, "VIMPAT": 8.219892698013998, "ZYPREXA": 2.5069869789393464, "null": 2.293455876797243}
\ No newline at end of file
+{"NAGLAZYME": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7762.json
index aa28aeabc33..189defefcaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7762.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7762.json
@@ -1 +1 @@
-{"INSULIN": 17.351661479221224, "JARDIANCE": 7.057045069208138, "null": 1.1728123288083834}
\ No newline at end of file
+{"ALEMTUZUMAB": 10.528263091770622, "AMIKACIN": 25.668700284221813, "ASPARAGINASE": 67.07912415846083, "BASILIXIMAB": 37.53034447575481, "BLINCYTO": 123.32032564269905, "BUDESONIDE": 1.9266684593213244, "BUSULFAN": 44.85203960277036, "CASPOFUNGIN": 130.04818223746466, "CELLCEPT": 6.754665126161076, "CICLOSPORIN": 27.275582581375584, "CRESEMBA": 52.345649742807865, "CYTARABINE": 34.97631926772645, "DEXAMETHASONE": 11.94999782846932, "EXJADE": 5.850057172938651, "LEVOFLOXACIN": 3.0662795098348026, "METHOTREXATE": 4.185117024974062, "MICAFUNGIN": 130.36712523267298, "MYCOPHENOLATE": 37.814590684748616, "NOXAFIL": 29.03308476274195, "POSACONAZOLE": 71.80780084153649, "VFEND": 16.050312198702812, "VORICONAZOLE": 77.5129449144517, "null": 0.2387629338208256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7763.json
index a8a14582442..bf878b39d8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7763.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7763.json
@@ -1 +1 @@
-{"JARDIANCE": 107.17586925621686}
\ No newline at end of file
+{"null": 2.729020642041075}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7764.json
index a6e9f9de85c..9d0248a0479 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7764.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7764.json
@@ -1 +1 @@
-{"OPTIMARK": 27.675873345745696}
\ No newline at end of file
+{"null": 1.2697170836939948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7765.json
index c4c7997dcc1..317c574ead9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7765.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7765.json
@@ -1 +1 @@
-{"ABILIFY": 2.3632228596190266, "ANAKINRA": 1.6022932238117304, "ASPARAGINASE": 1.1481669418568288, "BRIVARACETAM": 79.90432061527258, "BRIVIACT": 23.69646905937574, "BUCCOLAM": 66.22376736825215, "BUSULFAN": 1.7841760290971949, "CANNABIDIOL": 11.094669733373134, "CARBIDOPA": 4.062561850482366, "CICLOSPORIN": 1.706212747958893, "CUBICIN": 2.0710652700024363, "DEXAMETHASONE": 3.2885190921244374, "EFIENT": 7.218294834511043, "FAMPRIDINE": 12.605258572806523, "FAMPYRA": 9.810355066610304, "FENTANYL": 1.5724563669412217, "FYCOMPA": 26.01142895891065, "HUMAN": 3.756317920150319, "IBUPROFEN": 1.1866850325495526, "INOVELON": 67.63086970948213, "KEPPRA": 32.693094686613975, "KYMRIAH": 1.416007329925252, "LACOSAMIDE": 122.35488654171624, "LEVETIRACETAM": 60.64410459081636, "MIDAZOLAM": 15.10022263587256, "MMRVAXPRO": 1.3553591866898165, "TAMIFLU": 1.3755704167026124, "VIGABATRIN": 22.59161791463593, "VIMPAT": 22.31444620132796, "YESCARTA": 2.47426321594554, "ZYPREXA": 1.0827427104250489, "null": 1.5568330363447918}
\ No newline at end of file
+{"TWINRIX": 46.456491910898805, "null": 1.2568639635023566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7766.json
index 734b0f09888..3c69ec6cfce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7766.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7766.json
@@ -1 +1 @@
-{"AIMOVIG": 61.67360571409265, "COMIRNATY": 1.4064302103438038}
\ No newline at end of file
+{"ARAVA": 0.5231834143774367, "AVASTIN": 3.579454259021772, "BUSULFAN": 4.332313996273005, "COMIRNATY": 0.310683362639004, "EMEND": 21.41424078711642, "IBUPROFEN": 5.722286277135559, "KEPPRA": 1.1043242477667004, "KEYTRUDA": 1.7947046056089968, "MEPOLIZUMAB": 4.479125245023203, "METFORMIN": 28.135875336172823, "NEXAVAR": 2.252510641610624, "STIVARGA": 3.035452100708784, "SUTENT": 2.731132147698105, "TAGRISSO": 6.642481227070001, "TOZINAMERAN": 0.4249308905073121, "VAXZEVRIA": 0.1146030306240806, "null": 1.800164498668443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7767.json
index e06a4ca2487..c708b2f4aaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7767.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7767.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 32.999233738993965}
\ No newline at end of file
+{"ARAVA": 1.1393248607671205, "COMIRNATY": 0.5529822906192693, "COSENTYX": 1.93884442186294, "EMPAGLIFLOZIN": 51.46793241103668, "GARDASIL": 0.962452433643898, "JARDIANCE": 2.035637637687995, "OLANZAPINE": 3.956938407911127, "PEGASYS": 0.7268535196376866, "SPIKEVAX": 0.1667585677547154, "SUTENT": 1.9454330047576665, "VAXZEVRIA": 0.1457886727012816, "null": 1.866702671571126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7768.json
index 7f16243b89e..8be4d3b4ff5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7768.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7768.json
@@ -1 +1 @@
-{"AFINITOR": 10.769297673432783, "KAFTRIO": 66.80992277013985, "null": 1.917761348090994}
\ No newline at end of file
+{"CANCIDAS": 49.072009640340674, "CICATRIZANTS": 2307.4006469383025, "CICLOSPORIN": 5.178592660869899, "FORTIMEL": 3630.7298320394366, "KONTRASTMITTEL": 3914.518092932005, "null": 3.134701235286447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7769.json
index 4d21813ea68..1c4aa24830d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7769.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7769.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 24.66516696859416, "CICLOSPORIN": 12.310502992083835, "DARZALEX": 53.7192731154701, "EXJADE": 52.6131199819559, "FAMPYRA": 33.73663761805472, "ICLUSIG": 80.01820927072826, "SPRYCEL": 26.569155703680966}
\ No newline at end of file
+{"null": 3.0106193773912797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/777.json
index 41de31dc0af..2109e6c0dcf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/777.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/777.json
@@ -1 +1 @@
-{"AIMOVIG": 2.4242388451671504, "ALEMTUZUMAB": 15.36116696269174, "BETAFERON": 6.594795665515045, "BYETTA": 6.35488335425773, "COMIRNATY": 1.428127829036834, "GARDASIL": 6.604799007513588, "IPILIMUMAB": 24.84058458649042, "KALETRA": 5.556267392289751, "KEYTRUDA": 7.63963445084951, "LEMTRADA": 53.83191282055074, "OPDIVO": 10.513798600314455, "PEGASYS": 4.758853497458105, "PEGINTERFERON": 9.667195420543443, "PEGINTRON": 5.786724383722938, "PEMBROLIZUMAB": 11.73677481739524, "SAXENDA": 2.2262395950530425, "SOMATROPIN": 14.285540665721554, "STELARA": 1.4346829596756083, "TASIGNA": 2.6203686052422857, "TREMFYA": 3.512658247908428, "TWINRIX": 10.214820989657216, "XOLAIR": 1.270746637491642}
\ No newline at end of file
+{"ADALIMUMAB": 18.69818385239382, "ENBREL": 249.74425441225355, "null": 0.2773189014351571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7770.json
index 32358e9832d..c0fe5144c35 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7770.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7770.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 8.50364786324503, "ELIQUIS": 1.7848751454400222, "ENTYVIO": 8.55013479223735, "HUMIRA": 12.002309282281534, "OLANZAPINE": 5.312404302100536, "STELARA": 9.353939235822224, "TASIGNA": 11.210949488634633}
\ No newline at end of file
+{"CLOPIDOGREL": 9.841003312695188, "COMIRNATY": 0.2537239585405874, "NPLATE": 32.88185867075616, "PLAVIX": 3.65884702379696, "TOZINAMERAN": 0.4859598410784307, "VAXZEVRIA": 0.5360969802364416, "null": 1.1750355033781217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7771.json
index 203ab519c5b..87b7881039f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7771.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7771.json
@@ -1 +1 @@
-{"ACLIDINIUM": 263.0032296998307, "ASPARAGINASE": 18.551315214788676, "AZACITIDINE": 33.18064330827153, "BEDAQUILINE": 29.902730725323096, "BUDESONIDE": 27.50088727671389, "BUSULFAN": 11.479898729220585, "CASPOFUNGIN": 150.69390469640794, "CICLOSPORIN": 3.41461728012077, "CYTARABINE": 33.09178063487313, "LEVOFLOXACIN": 6.038687055799206, "ORKAMBI": 40.120419749451166}
\ No newline at end of file
+{"null": 2.612792112704738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7772.json
index a0755fe86c2..d9e68b29a5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7772.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7772.json
@@ -1 +1 @@
-{"PLAVIX": 29.02105724509085, "null": 1.582629047157575}
\ No newline at end of file
+{"COMIRNATY": 0.5646557524171147}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7773.json
index c86cf6135c9..3a8e92acc52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7773.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7773.json
@@ -1 +1 @@
-{"ANAKINRA": 13.54151920680213, "APIXABAN": 1.2534161295888484, "AVAMYS": 11.597411926819522, "AVANDAMET": 73.18778338968191, "AVANDIA": 76.16923964738442, "BYETTA": 6.044070256644217, "CELECOXIB": 7.906886363784955, "CLOPIDOGREL": 3.002922545190721, "ELIQUIS": 3.53926434615937, "ENTRESTO": 1.3297527623286096, "HIZENTRA": 5.323996691807925, "HUMALOG": 1.3765406054771707, "INCRUSE": 6.058443078894984, "JANUMET": 4.660968495449603, "JANUVIA": 8.122769349342567, "JARDIANCE": 1.3341297063277382, "LANTUS": 4.091713715909145, "LEVEMIR": 2.9597525650870518, "MEPOLIZUMAB": 2.55283369972592, "OPSUMIT": 2.8128606993852032, "PLAVIX": 12.499347093002909, "RANOLAZINE": 95.27640926373576, "STELARA": 1.1140599127339128, "TRACLEER": 1.752413160794044, "TRELEGY": 9.643797786020706, "VELTASSA": 5.932678121856803, "VOTRIENT": 1.153720657217225, "XTANDI": 4.0106960763241775, "ZOSTAVAX": 2.2969317012684654}
\ No newline at end of file
+{"ABATACEPT": 0.3844623282631814, "ABRAXANE": 4.013792314933522, "ADALIMUMAB": 0.2945846747173579, "AFINITOR": 17.804126521012517, "ALEMTUZUMAB": 21.679994003322246, "ALIMTA": 20.667109300032763, "ALPELISIB": 7.85130941763764, "ARAVA": 0.3394999747515271, "ARIPIPRAZOLE": 4.5176221207316765, "ASPARAGINASE": 6.362803053901457, "ATEZOLIZUMAB": 19.525527304589797, "AUTOLOGOUS": 248.2440796808056, "AVASTIN": 5.773138398928983, "AVELUMAB": 11.506867451942869, "AXITINIB": 10.232368942309977, "AZACITIDINE": 2.2990966643045407, "BEVACIZUMAB": 9.182907809795529, "BORTEZOMIB": 10.07119456556988, "BUSILVEX": 48.793652386192434, "BUSULFAN": 47.52128932145993, "CABOMETYX": 11.87565139913368, "CAELYX": 16.872895737343462, "CAPECITABINE": 12.138040529391828, "CARFILZOMIB": 3.486386134200535, "CARMUSTINE": 34.98697437223768, "CELLCEPT": 0.6555855842067387, "CETUXIMAB": 12.816613870387014, "CICLOSPORIN": 3.778116220497804, "CLOFARABINE": 10.625306983762046, "COMIRNATY": 0.0446990188527483, "COSENTYX": 0.7679060024995668, "COTELLIC": 8.15032580005422, "CYTARABINE": 15.740472236651442, "DABRAFENIB": 6.212920658691106, "DENOSUMAB": 9.880017584135532, "DEXAMETHASONE": 3.902193038145702, "DOCETAXEL": 11.178585162236107, "DOXORUBICIN": 6.448123299390503, "EMEND": 5.61541955424712, "ENBREL": 0.3268642471575876, "ERBITUX": 19.15913965359837, "EVEROLIMUS": 11.204110676464571, "FASLODEX": 1.676010634713908, "FILGRASTIM": 12.74216972681663, "FOTIVDA": 15.17872435955698, "FULVESTRANT": 4.879185308676102, "HALAVEN": 16.62397688200028, "HERCEPTIN": 8.114971067489925, "IBRANCE": 3.053797236216902, "IBUPROFEN": 0.4688192390038686, "IMATINIB": 2.353545219966935, "INLYTA": 3.990599265402368, "IPILIMUMAB": 1.2337836638754225, "IRESSA": 0.9380587515476552, "IRINOTECAN": 16.56662714157192, "JEVTANA": 4.148808423897667, "KALETRA": 1.3069572319959315, "KEPPRA": 0.1366656150972956, "KEYTRUDA": 2.7286258499253355, "KISQALI": 2.0309088798652577, "KYMRIAH": 0.9602613350510286, "LENVIMA": 6.065694936931237, "LEVETIRACETAM": 0.3092137293554674, "LEVOFLOXACIN": 0.3732493121017593, "LONSURF": 1.00364797099502, "MABTHERA": 4.347918998995172, "MEKINIST": 1.3085735182590257, "MELPHALAN": 29.711473393345468, "MERCAPTOPURINE": 5.426696409807521, "METHOTREXATE": 6.071559249894912, "MICARDIS": 0.6996956503411345, "MYCOPHENOLATE": 1.731430403067021, "NEULASTA": 3.682606829417447, "NEXAVAR": 4.406268651420727, "NORVIR": 1.4921206402848182, "NOXAFIL": 2.6580712168914555, "OPDIVO": 0.805817321703677, "OSIMERTINIB": 9.77079322761784, "PACLITAXEL": 2.8878591677951824, "PAZOPANIB": 2.913754855245118, "PEGFILGRASTIM": 13.12904535157648, "PEMBROLIZUMAB": 5.087410200169902, "PEMETREXED": 7.7321859486767535, "PIQRAY": 7.152458026021125, "RADIATION": 20.097733810354235, "REGORAFENIB": 16.534102229623297, "RITUXIMAB": 2.7023927870343023, "SORAFENIB": 8.28979992726653, "SPIKEVAX": 0.0325772894780098, "SPRYCEL": 0.8097906768709846, "STIVARGA": 9.972290900157718, "SUNITINIB": 17.0382805141317, "SUTENT": 10.791174927467528, "TAGRISSO": 3.283513389119108, "TAXOTERE": 10.3136214171609, "TEMODAL": 2.4011345527312358, "TEMOZOLOMIDE": 3.8913693932643, "TEMSIROLIMUS": 15.267585899345825, "TEPADINA": 61.453650752156, "THERAPEUTIC": 27.58822158590593, "THIOTEPA": 62.6153191884963, "TOPOTECAN": 10.095124714877947, "TORISEL": 8.135266549182274, "TRODELVY": 16.592205532591443, "VAXZEVRIA": 0.0206145004942931, "VECTIBIX": 9.803165973594096, "VIRAMUNE": 3.400807573853644, "VOTRIENT": 5.686589905217481, "XELODA": 12.440914443245743, "ZELBORAF": 2.962792836266497, "null": 0.6267680825391236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7774.json
index 395b645b4b8..b9f9dd82b1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7774.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7774.json
@@ -1 +1 @@
-{"AVAMYS": 12.715941350773315, "CARBIDOPA": 65.55914192338523, "FENTANYL": 7.884847136989245, "LEVODOPA": 185.73751418975763, "SIFROL": 174.20719820759956, "STALEVO": 36.10581657759274, "null": 2.145870014739728}
\ No newline at end of file
+{"null": 4.007718127168797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7775.json
index 2410bb49669..8484fc9581d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7775.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7775.json
@@ -1 +1 @@
-{"null": 1.2687455096402631}
\ No newline at end of file
+{"null": 1.9648859654261528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7776.json
index e0ad203c8ad..398a4c26bd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7776.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7776.json
@@ -1 +1 @@
-{"AIMOVIG": 82.93110268535288, "FORSTEO": 6.404162111241828, "TRUVADA": 2.4495776499485835}
\ No newline at end of file
+{"COMIRNATY": 0.5390924923705618, "VAXZEVRIA": 0.7792796753023612, "null": 0.8541545160221466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7777.json
index 54ff34627e4..aa38c531f9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7777.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7777.json
@@ -1 +1 @@
-{"ADALIMUMAB": 60.33228946518284, "AZATHIOPRINE": 26.86950048888321, "ENTYVIO": 34.9143498548905, "HUMIRA": 31.95986689950306}
\ No newline at end of file
+{"null": 1.2714126242747026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7778.json
index 8674c299578..112b7f5c3be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7778.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7778.json
@@ -1 +1 @@
-{"ASPARAGINASE": 12.635004786601137, "CELLCEPT": 19.06829886451219, "CICLOSPORIN": 19.856322437971297, "DEXAMETHASONE": 7.5867552321682625, "DUPILUMAB": 586.56256011252, "OPDIVO": 7.85353687757981}
\ No newline at end of file
+{"null": 0.4899686106318595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7779.json
index 4c188481fb6..03e148fc228 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7779.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7779.json
@@ -1 +1 @@
-{"HYDROCORTISONE": 475.4832521146338, "PROTOPIC": 423.2148123488931, "null": 2.6015593138509443}
\ No newline at end of file
+{"CICLOSPORIN": 7.706284331885433, "FENTANYL": 5.4496284278696905, "null": 1.7144398648253445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/778.json
index cb1f27e5778..797e80eb935 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/778.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/778.json
@@ -1 +1 @@
-{"ANAKINRA": 238.03094422202145, "CYMBALTA": 10.511774389891716, "METHOTREXATE": 29.169554532888203}
\ No newline at end of file
+{"ACLIDINIUM": 42.63497667938178, "ARANESP": 380.42503665889166, "SPIKEVAX": 4.801049691437267, "ZOSTAVAX": 36.981120219887366, "null": 0.1076659113633177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7780.json
index b4b0d5003b2..2e41a7852a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7780.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7780.json
@@ -1 +1 @@
-{"COMIRNATY": 1.578445128436664}
\ No newline at end of file
+{"AMINOSALICYLIC": 4.805222502931265, "BUDESONIDE": 2.4453969538567577, "CLOPIDOGREL": 1.8909816540345157, "COMIRNATY": 0.2133144920358694, "COSENTYX": 2.5295805737184813, "ENTYVIO": 46.72307567025556, "HUMIRA": 5.422342719814067, "LEFLUNOMIDE": 20.977263298524772, "PREVENAR": 16.397799391602057, "REMSIMA": 230.5545196447674, "ROTATEQ": 198.6830155109137, "SIMPONI": 3.042904488620355, "SPIKEVAX": 0.1752880659180615, "SUTENT": 0.6582739591484937, "TOZINAMERAN": 0.6232705330734114, "VAXZEVRIA": 0.1070923972482831, "XELJANZ": 12.604220810000747, "null": 1.005348197383205}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7781.json
index a105f73c63e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7781.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7781.json
@@ -1 +1 @@
-{"1": 67.16782399335501, "ACTOS": 1.9933778980358352, "ACTRAPID": 4.597069127557772, "ADENURIC": 2.026528621078504, "AERIUS": 1.8338547191081385, "ALIMTA": 1.7591816061815493, "ALL": 4.412685173382017, "AMIKACIN": 3.107716393098529, "APROVEL": 1.9106330264318712, "BIKTARVY": 1.6966404464377736, "CANCIDAS": 6.4233581175141, "CASPOFUNGIN": 1.3237066770891626, "COMBIVIR": 4.075784392133059, "COTELLIC": 10.40663698851975, "CUBICIN": 5.294157804415451, "DEXAMETHASONE": 1.4476529361460542, "EFAVIRENZ": 1.5449792102560806, "EMEND": 4.661525762191892, "EMTRICITABINE": 1.7243482076413978, "EPIVIR": 1.2612078047504378, "ERLEADA": 9.09402242960422, "ESOMEPRAZOLE": 1.3269297118415015, "FEBUXOSTAT": 11.081747040054172, "FENTANYL": 1.8683217565655137, "FORTIMEL": 147.1076537627112, "HALAVEN": 2.142005525052563, "HYDROCHLOROTHIAZIDE": 5.435724155453702, "HYDROCORTISONE": 1.3783850638879045, "IBUPROFEN": 7.2422166461939534, "INCIVO": 1.159691580507321, "INSUMAN": 6.057229131990138, "INVIRASE": 5.18114460238931, "ISENTRESS": 1.6146213187555651, "KALETRA": 1.51456830109226, "KEPPRA": 5.127180131332464, "KEYTRUDA": 3.947256634557669, "KONTRASTMITTEL": 241.22462686802143, "LACOSAMIDE": 3.641457700222728, "LAMIVUDINE": 6.610783681243444, "LEVETIRACETAM": 3.699917652129902, "LEVOFLOXACIN": 4.659642703872933, "LYRICA": 1.1414485319657373, "MICARDIS": 2.0262689667685527, "MIRCERA": 2.059709091711614, "NEVIRAPINE": 86.68310203512402, "NEXAVAR": 2.570901837935917, "NOVONORM": 2.516191609823207, "OPDIVO": 2.238393996782843, "OSELTAMIVIR": 4.290335738141466, "PANTOPRAZOLE": 1.3247866505821229, "PEGASYS": 1.1537215264462763, "PEGINTERFERON": 2.3941538326788865, "PEMBROLIZUMAB": 2.8707566242744376, "PLAVIX": 1.3743287404275872, "PROTELOS": 2.2426525988984025, "RADIATION": 5.863591174985291, "REVLIMID": 1.76565626760605, "RIBAVIRIN": 1.027795690614819, "RISPERIDONE": 1.937517840917626, "SIFROL": 2.3956492362203927, "SORAFENIB": 4.156051349482739, "SPIRONOLACTONE": 12.230220316617617, "STIVARGA": 2.54660755667294, "TAGRISSO": 1.598085770845456, "TAMIFLU": 8.785857829085096, "TELBIVUDINE": 235.45859548184885, "TEMODAL": 7.510492167622416, "THALIDOMIDE": 1.995580443552428, "TORISEL": 1.3524630683071444, "UNKNOWN": 6.515991760576148, "VFEND": 2.270270184655644, "VIMPAT": 2.080520459582734, "VIRAMUNE": 69.85535057626883, "VORICONAZOLE": 1.469764241195335, "ZELBORAF": 3.0037555079773863, "ZONISAMIDE": 7.613532078378639, "null": 3.639609527367122}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7782.json
index c795c3af0db..acf324caf76 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7782.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7782.json
@@ -1 +1 @@
-{"null": 2.6900865223538863}
\ No newline at end of file
+{"ANIDULAFUNGIN": 149.71178760117215, "COMIRNATY": 0.17807948315001, "ESOMEPRAZOLE": 26.70881359727129, "HUMALOG": 49.34086747334072, "INSULIN": 10.69036126527132, "PEMBROLIZUMAB": 20.003984388988357, "null": 0.8046308762262362}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7783.json
index 3a0541bc88c..751543a20d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7783.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7783.json
@@ -1 +1 @@
-{"COVID19": 3.630344785372946}
\ No newline at end of file
+{"null": 0.4491125594149601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7784.json
index b3ce6abea3b..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7784.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7784.json
@@ -1 +1 @@
-{"COMIRNATY": 1.476866563147164}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7785.json
index a814a015093..d7fa2272605 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7785.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7785.json
@@ -1 +1 @@
-{"ANAKINRA": 38.56846597662207, "CICLOSPORIN": 6.344682318531322, "ENBREL": 6.96323714412827, "GARDASIL": 2.8314761302845426, "METHOTREXATE": 11.21360636009102, "TOZINAMERAN": 2.2112284861137934, "VAXZEVRIA": 1.8289656452668657}
\ No newline at end of file
+{"ENVARSUS": 960.2672617602084, "LANTUS": 4.357250057843152, "NPLATE": 70.97405534452291, "SOLIRIS": 34.603260520172654, "null": 0.6142900664051913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7786.json
index cd9329ceb97..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7786.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7786.json
@@ -1 +1 @@
-{"ABACAVIR": 1.508943616746021, "ATOSIBAN": 98.94594387338395, "BUPRENORPHINE": 4.073437245769126, "CIMZIA": 1.1242007567621373, "COMBIVIR": 57.30267273245861, "CYTARABINE": 2.4237329318908407, "EFAVIRENZ": 25.428185495863296, "ENTYVIO": 2.776871697956669, "HUMALOG": 1.123098622763797, "ISENTRESS": 28.644168483602567, "KALETRA": 20.99932324733667, "KEPPRA": 2.357729955872664, "LAMIVUDINE": 19.76986616190751, "LEVEMIR": 4.949026992548856, "LEVETIRACETAM": 5.663763222584945, "MIDAZOLAM": 8.019766682692266, "NEVIRAPINE": 35.25322250807682, "NORVIR": 18.583614530309685, "OSELTAMIVIR": 70.6872639638126, "REMICADE": 9.583123129392495, "SUBOXONE": 6.489649232193317, "TAMIFLU": 3.74995180581302, "XOLAIR": 2.539588048741906, "null": 1.6828233149682397}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7787.json
index 693ff3cb435..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7787.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7787.json
@@ -1 +1 @@
-{"REVESTIVE": 3463.132671985337, "null": 1.1189453449891842}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7788.json
index 5c54809b054..ddf395d8bd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7788.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7788.json
@@ -1 +1 @@
-{"null": 2.59950973928883}
\ No newline at end of file
+{"ABATACEPT": 1.4487819751786564, "ACTOS": 34.292948131753434, "APIXABAN": 10.351170296258497, "ARAVA": 2.30733063975026, "BELIMUMAB": 91.81517002415158, "BENLYSTA": 4.533598841618911, "BUDESONIDE": 12.947290673729622, "CANAGLIFLOZIN": 82.61513393612219, "COMIRNATY": 0.3509910196605444, "FASENRA": 5.327407539508856, "HUMALOG": 1.1206421615466298, "INCRUSE": 15.7555353573988, "INVOKANA": 19.399175792702227, "JANUMET": 3.916353047023783, "MEPOLIZUMAB": 17.8668619402784, "NUCALA": 10.540513823233749, "OMALIZUMAB": 6.43060049207873, "OPSUMIT": 2.698424860276281, "SPIKEVAX": 0.1116721081451022, "TOZINAMERAN": 0.2512058911448349, "VAXZEVRIA": 0.1584992684108161, "XOLAIR": 1.5511578750495305, "null": 1.428833644475843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7789.json
index 51f72a3c1bd..d6a060ab6fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7789.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7789.json
@@ -1 +1 @@
-{"AVASTIN": 53.2552137640838, "BEVACIZUMAB": 37.741938975966605, "ELIQUIS": 9.091236336200415, "STIVARGA": 53.40505685373885}
\ No newline at end of file
+{"MMRVAXPRO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/779.json
index 3125797fcab..04d51b89f75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/779.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/779.json
@@ -1 +1 @@
-{"null": 1.898168277963535}
\ No newline at end of file
+{"null": 13.24772317388654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7790.json
index 13976e7ad9a..5cbc5b1103f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7790.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7790.json
@@ -1 +1 @@
-{"null": 2.2274077408538293}
\ No newline at end of file
+{"SUBOXONE": 62.21856163151718, "null": 2.1368762975438496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7791.json
index cb27efd82fb..14f6ecff57b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7791.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7791.json
@@ -1 +1 @@
-{"null": 1.0472260051202753}
\ No newline at end of file
+{"KEPPRA": 3.346513874524378, "SUBOXONE": 3.3338876533368818, "null": 9.810079746025044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7792.json
index 0f601593120..d6ba1695cfc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7792.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7792.json
@@ -1 +1 @@
-{"null": 1.9147619606564508}
\ No newline at end of file
+{"ALISKIREN": 163.32787132305566, "AMLODIPINE": 1266.7035623438549, "CAFFEINE": 1276.726816297091, "LANTUS": 2.1111048761125075, "LEVOFLOXACIN": 165.57965488429298, "RISPERIDONE": 41.009342614502486, "null": 0.6996226011315396}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7793.json
index 418ddc267c0..9828bff7904 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7793.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7793.json
@@ -1 +1 @@
-{"BYETTA": 30.33225054146053, "null": 1.1419080644232673}
\ No newline at end of file
+{"ABATACEPT": 0.2060958616069841, "ADALIMUMAB": 0.1800980600937087, "ARAVA": 0.0251577277093842, "ATRIPLA": 63.594116006248285, "AVANDIA": 0.2705220328766245, "DESCOVY": 1.7334997563519987, "ELIQUIS": 0.0486678917438797, "ENBREL": 0.2329801503767664, "EVENITY": 1.0947226002475956, "EVISTA": 0.9017192366273836, "FORSTEO": 0.2255731037696689, "GENVOYA": 1.4089336831084067, "HEPSERA": 3.6000743399115893, "HUMALOG": 0.0743853241354594, "IBRANCE": 0.0518182480501266, "KALETRA": 6.505344743490132, "KEPPRA": 0.0546070215277754, "LANTUS": 0.0945203522431063, "LYRICA": 0.0929170466538593, "STRIBILD": 39.76729575086082, "TRUVADA": 66.22581992318202, "VIREAD": 15.613076504346932, "XOLAIR": 0.0776346464994652, "null": 0.0261072815328445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7794.json
index a64a989cffb..422b1ed161e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7794.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7794.json
@@ -1 +1 @@
-{"null": 1.550517434167808}
\ No newline at end of file
+{"ATRIPLA": 1.8024558838241345, "BUPRENORPHINE": 2.9045386389607133, "COMIRNATY": 0.0647862578908066, "PLAVIX": 352.419921339594, "TRUVADA": 0.5694718743802276, "null": 0.843926947940495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7795.json
index 44ee1320ea3..9e3bf370e3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7795.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7795.json
@@ -1 +1 @@
-{"ABATACEPT": 6.810092634839062, "ABRAXANE": 5.317968489156255, "ADALIMUMAB": 2.2114815741302283, "AFINITOR": 30.129564049329097, "AFLIBERCEPT": 8.93862400427411, "ALIMTA": 3.789363909776583, "ANAKINRA": 3.225649236251964, "APREMILAST": 1.6886669792325653, "ARAVA": 2.098328157452735, "ASPARAGINASE": 3.141583824361632, "ATEZOLIZUMAB": 2.092740406991724, "AVASTIN": 5.90089126977439, "AVELUMAB": 2.1646869755117897, "AXITINIB": 5.030058807297966, "AZACITIDINE": 1.1255604120710558, "BAVENCIO": 5.269570493226762, "BENLYSTA": 1.1995496261599796, "BEVACIZUMAB": 3.557000017307568, "BOCEPREVIR": 2.082148023449525, "BOSULIF": 1.2727776605566898, "BUSILVEX": 14.75385260905805, "BUSULFAN": 7.1454754010075545, "CABOMETYX": 12.120922883337869, "CAELYX": 7.331746732032793, "CAPECITABINE": 2.878715761421417, "CARMUSTINE": 4.7923938226571625, "CETUXIMAB": 8.258065864036862, "CHLORHEXIDINE": 31.583404049166408, "CIMZIA": 9.703749423925144, "CLOFARABINE": 2.4413089805958617, "COSENTYX": 1.3714720878298896, "COTELLIC": 4.336394529183146, "CYTARABINE": 2.975252445554612, "DOCETAXEL": 4.552268820396817, "DOXORUBICIN": 2.149192234639877, "ERBITUX": 12.891272562471556, "EVEROLIMUS": 5.36391854486605, "FASLODEX": 2.4537005814080484, "FILGRASTIM": 1.0036509005883627, "FOTIVDA": 5.376051162405831, "FULVESTRANT": 1.892926136253516, "HALAVEN": 17.90495874411765, "HERCEPTIN": 2.890219508815301, "IBRANCE": 7.54643731533004, "IMATINIB": 2.403518240615583, "INLYTA": 8.62823276822617, "IRESSA": 6.556163017751702, "IRINOTECAN": 7.914997377245134, "KEYTRUDA": 4.168139959605727, "KISQALI": 1.1199195832279123, "LENVIMA": 6.3551049915749855, "LONSURF": 1.2887126074124011, "LYNPARZA": 2.2713300490759063, "MABTHERA": 1.7756033951442745, "MELPHALAN": 5.63676359675866, "MERCAPTOPURINE": 2.3046891723574965, "METHOTREXATE": 2.782426752131696, "NEXAVAR": 4.845770834726587, "OPDIVO": 1.6956424793770577, "ORENCIA": 1.8345316396428584, "PACLITAXEL": 1.023006428107888, "PANITUMUMAB": 14.775462739678083, "PAZOPANIB": 1.7092680977737222, "PEGASYS": 1.8111204491465305, "PEGFILGRASTIM": 2.6350230536707504, "PEGINTERFERON": 1.436549979782193, "PEGINTRON": 1.4949874138787649, "PEMBROLIZUMAB": 1.892922688539308, "PEMETREXED": 1.9675731400345404, "PIQRAY": 6.4326821372027245, "PROTELOS": 2.634610828716776, "RAPAMUNE": 2.3711252314244207, "REBETOL": 1.1239611226811483, "REGORAFENIB": 9.67790234399723, "RELVAR": 1.617926026063924, "RIBOCICLIB": 1.0132377894195366, "RITUXIMAB": 1.632180858492499, "RUBRACA": 1.5361693042073064, "SORAFENIB": 1.8617317016067705, "STIVARGA": 6.527626139106558, "SUNITINIB": 4.320431895169893, "SUTENT": 10.170597585774994, "TAGRISSO": 5.472740746696174, "TAXOTERE": 9.298416330429918, "TEMSIROLIMUS": 47.4149557735368, "THERAPEUTIC": 13.94546001504778, "THIOTEPA": 5.199218308356958, "TOPOTECAN": 2.4378322198150792, "TORISEL": 6.7169809363216375, "TRODELVY": 2.156881394561052, "VECTIBIX": 17.432560332732237, "VOTRIENT": 3.571288332668986, "XELODA": 5.051706541413796, "ZELBORAF": 1.53447209008042}
\ No newline at end of file
+{"APIDRA": 366.73590227594497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7796.json
index e77e16bc08b..aa2d1201b3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7796.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7796.json
@@ -1 +1 @@
-{"null": 1.6852987521715004}
\ No newline at end of file
+{"ABACAVIR": 0.1978468031530635, "ADALIMUMAB": 0.0298784993921124, "ADVAGRAF": 7.869716801234381, "AFINITOR": 0.9354661448953604, "ALEMTUZUMAB": 9.257795103094058, "ALIMTA": 1.574230678736814, "ALL": 5.4626420270326665, "AMIKACIN": 7.609418994484369, "ANIDULAFUNGIN": 32.04139621301433, "APROVEL": 2.071835076797017, "ARANESP": 13.431323845673074, "ARAVA": 0.2082585660499034, "ARIPIPRAZOLE": 0.2523421204863257, "ASPARAGINASE": 6.308935013096033, "AUBAGIO": 0.1785120744450214, "AUTOLOGOUS": 40.39871300762043, "AVANDIA": 0.7631400943163111, "AVASTIN": 1.8516954444522824, "AZACITIDINE": 4.130361469672551, "AZATHIOPRINE": 0.9263448491685022, "AZTREONAM": 6.5848186566809535, "BASILIXIMAB": 10.207100041941702, "BEDAQUILINE": 0.9268418283497524, "BENLYSTA": 0.6080414024107584, "BOCEPREVIR": 3.90012924023044, "BORTEZOMIB": 5.786790440888698, "BOSENTAN": 4.439462878133713, "BRIDION": 0.8347983411448259, "BRILIQUE": 1.2560064810467584, "BUDESONIDE": 1.1237937085750695, "BUMETANIDE": 3.3194734821854173, "BUPRENORPHINE": 0.5743504085272332, "BUSILVEX": 7.743620550804389, "BUSULFAN": 10.278733380784056, "BYETTA": 1.2439782015027887, "CAELYX": 1.576729842066184, "CANCIDAS": 18.17512832966768, "CAPECITABINE": 0.8609758174882077, "CARFILZOMIB": 4.015118981506092, "CARMUSTINE": 1.985214812470636, "CASPOFUNGIN": 24.598947909825156, "CELLCEPT": 3.834740060913879, "CICATRIZANTS": 88.44252085104105, "CICLOSPORIN": 7.558064592615327, "CIMZIA": 0.1151873180604396, "CLADRIBINE": 6.776406454162983, "CLOFARABINE": 18.03431775606538, "CLOPIDOGREL": 0.9589142640947124, "COMIRNATY": 0.0991278956885298, "COSENTYX": 0.2390206221629794, "CRESEMBA": 4.9517323139424425, "CRIXIVAN": 2.544399455236729, "CUBICIN": 8.244554343151947, "CYMBALTA": 0.2336229844666411, "CYTARABINE": 6.739153860369067, "DAPTOMYCIN": 11.07517215059124, "DARBEPOETIN": 37.97844336770435, "DARZALEX": 0.8429239524759279, "DEFITELIO": 75.27726498668905, "DESLORATADINE": 2.172706433892237, "DEXAMETHASONE": 4.886679967941557, "DEXMEDETOMIDINE": 8.805195481335653, "DIFICLIR": 4.835982362881562, "DOCETAXEL": 0.6398622953626448, "DOXORUBICIN": 2.420876958207874, "ELIQUIS": 0.649428708972933, "EMTRICITABINE": 2.134475171057049, "ENOXAPARIN": 0.7501500271258442, "ENTRESTO": 0.9905622049759036, "ENTYVIO": 0.4726527737675244, "EPIVIR": 1.33147316154783, "ESOMEPRAZOLE": 2.3902600103538933, "EVEROLIMUS": 1.839218981175441, "EXJADE": 2.6130449156549465, "EXVIERA": 1.4956797181030197, "FASLODEX": 1.0801965986562432, "FENTANYL": 1.8272382413970047, "FILGRASTIM": 5.779657534825653, "FLUTICASONE": 9.010254218856833, "FORSTEO": 0.4403665435997247, "FORXIGA": 0.2702720001694954, "GALVUS": 1.383143387660711, "GANCICLOVIR": 11.93025485977306, "GARDASIL": 0.0791034459001792, "HARVONI": 0.6545295662881002, "HUMALOG": 0.1745051314751832, "HUMAN": 1.4277513694882993, "HYDROCORTISONE": 3.530654857521362, "IBRANCE": 0.2333728902488505, "IBUPROFEN": 2.379473465686365, "ICLUSIG": 2.38448957811382, "INCIVO": 3.2953642402732037, "INSULIN": 0.3286406978631771, "INTEGRILIN": 3.976621746033693, "INTELENCE": 3.835737953232934, "IPILIMUMAB": 1.03351463665802, "IRESSA": 1.0429952400927809, "IRINOTECAN": 0.6730283020159182, "JAKAVI": 2.6158106544859736, "JANUMET": 0.698310649411351, "JANUVIA": 0.6277387789337703, "JARDIANCE": 0.4895512438137825, "JEVTANA": 4.186135230579333, "KALETRA": 0.9233110739975404, "KEPPRA": 1.3560656911753637, "KEYTRUDA": 1.3855409405534571, "KYMRIAH": 5.148071230720524, "KYPROLIS": 1.452541989591628, "LACOSAMIDE": 2.147959179417983, "LAMIVUDINE": 1.1046224461828442, "LANTUS": 0.4453503817795444, "LEMTRADA": 0.4656905384314412, "LEVETIRACETAM": 2.963596066497437, "LEVOFLOXACIN": 3.0909346724797357, "LYNPARZA": 0.5366379726671927, "MABTHERA": 2.6259913780759443, "MEKINIST": 0.8736630406051253, "MELATONIN": 1.6653194738424029, "MELPHALAN": 7.120862460936055, "METHOTREXATE": 1.7152112899353391, "MICAFUNGIN": 9.906876627679932, "MICARDIS": 0.9301947408451164, "MIDAZOLAM": 2.6501403556387624, "MULTAQ": 1.785380298859692, "MYCAMINE": 10.737063867899556, "MYCOPHENOLATE": 4.072562385233291, "NEXAVAR": 1.2248566736118716, "NOVOSEVEN": 39.48044985677456, "NOXAFIL": 2.4287226916008247, "NPLATE": 1.763015893076058, "OLANZAPINE": 0.6129252623203545, "OLYSIO": 2.102722631470594, "ONCASPAR": 2.4180213598553766, "OPDIVO": 1.0352766194827627, "OPSUMIT": 2.114771390341306, "OPTIMARK": 0.2523107194792767, "PANTOPRAZOLE": 1.529022343384664, "PEGASYS": 1.3005145865086911, "PEGINTERFERON": 1.2611730454055097, "PEGINTRON": 1.0079927070524928, "PEMBROLIZUMAB": 1.2755263985220335, "PEMETREXED": 1.2317201125894954, "PLAVIX": 1.2597842762005893, "POSACONAZOLE": 4.38267615005681, "PRADAXA": 2.8223763014192222, "PRAXBIND": 20.3051244338344, "PRIVIGEN": 0.4489400674685685, "RAPAMUNE": 1.3834534261843916, "RASILEZ": 1.1271517461958918, "REBETOL": 2.1585928739019797, "REMDESIVIR": 6.555047317974364, "REMICADE": 0.979474441008742, "REVATIO": 2.164120203446809, "REVLIMID": 1.3820285839020745, "RIBAVIRIN": 1.039473684577101, "RITUXIMAB": 1.2849718360872742, "ROACTEMRA": 3.063184645103107, "RUXOLITINIB": 1.816948299538206, "SAMSCA": 6.9206296233715205, "SILDENAFIL": 0.7070085652517831, "SIMPONI": 0.1608431068875181, "SODIUM": 10.636908014887943, "SOLIRIS": 5.580668908764598, "SOVALDI": 2.8095887428918456, "SPIKEVAX": 0.0847039403587335, "SPINRAZA": 0.6859421460914182, "SPIRONOLACTONE": 2.988094860664582, "SPRYCEL": 0.6783400820760069, "STELARA": 0.3635734329568857, "STIVARGA": 0.676012348289967, "SUBOXONE": 0.2113249530733534, "SUTENT": 2.706232919341803, "SYNAGIS": 1.6297013213242737, "TACROLIMUS": 2.2936034813393302, "TAMIFLU": 3.639019186038419, "TASIGNA": 0.5642158253376174, "TEMODAL": 2.082849472234703, "TENOFOVIR": 2.5388572546855173, "THIOTEPA": 4.057598456527057, "TICAGRELOR": 1.299177530476449, "TOBRAMYCIN": 3.664853757759001, "TOCILIZUMAB": 1.9555080877346824, "TOZINAMERAN": 0.1116592015384098, "TRACLEER": 3.7653623141773607, "VAXZEVRIA": 0.0627858746175078, "VEKLURY": 7.190293377341101, "VENCLYXTO": 4.877874921754071, "VENETOCLAX": 2.474981630352914, "VFEND": 2.560230636961792, "VICTOZA": 0.4220426582258359, "VIMPAT": 0.6697307244772589, "VIREAD": 0.5798999530769139, "VORICONAZOLE": 4.690752964401965, "VOTRIENT": 0.7118995167332971, "XALKORI": 1.4613011568977283, "XARELTO": 0.6331546736078775, "XELJANZ": 0.135262265952264, "XELODA": 1.7015464730866168, "XOLAIR": 0.1643899930657873, "XTANDI": 0.5665797551733488, "YERVOY": 1.166185455095715, "YESCARTA": 3.287513838781345, "YONDELIS": 8.030080488581554, "ZYPREXA": 0.3240012862615268, "null": 1.2110618689118726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7797.json
index 9d8f4cd7c25..ed49ef079d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7797.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7797.json
@@ -1 +1 @@
-{"BUPIVACAINE": 72.02881007937688, "CARIPRAZINE": 137.18559849467545, "INFANRIX": 22.238659704767255, "KALETRA": 5.1745785556216495, "KEPPRA": 1.6794613834461696, "KEYTRUDA": 1.3826382315305314, "MMRVAXPRO": 6.805512796656956, "TAMIFLU": 4.624468574170573, "ZOSTAVAX": 1.3550444011056204, "null": 3.0740171733859394}
\ No newline at end of file
+{"null": 2.0662328460057404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7798.json
index f3fff1f1ca6..3d59b4a7f33 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7798.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7798.json
@@ -1 +1 @@
-{"null": 7.878652582336181}
\ No newline at end of file
+{"ADALIMUMAB": 0.1117859660993742, "AIMOVIG": 1.875282013288076, "ALEMTUZUMAB": 2.964128517586913, "AUBAGIO": 142.97661443525362, "AVONEX": 51.35890540942624, "BETAFERON": 69.19632833547284, "BUPRENORPHINE": 0.5241203553141188, "CHAMPIX": 1.0950916010004663, "CIMZIA": 0.8882414533927604, "CLADRIBINE": 8.697898074090764, "COMIRNATY": 0.5584263698027077, "COSENTYX": 0.9090671674065316, "CYMBALTA": 0.6918714681394782, "ELIQUIS": 0.2344228372139997, "ENBREL": 0.798027868920765, "ENTYVIO": 0.6026748422783219, "FAMPRIDINE": 34.75634760554862, "FAMPYRA": 55.673392988000536, "GARDASIL": 7.000328285493678, "GILENYA": 15.36785179420972, "HUMALOG": 1.2021454840910877, "HUMIRA": 2.376827109208046, "IBRANCE": 0.2494784113877783, "JARDIANCE": 0.3425532246677192, "KEPPRA": 0.6745883344665256, "KESIMPTA": 50.33137836897392, "KEYTRUDA": 0.2164589073350888, "LANTUS": 0.475116796877741, "LATUDA": 0.964841267134228, "LEMTRADA": 17.252470565206767, "LYRICA": 2.5903590667814145, "MAVENCLAD": 77.4803866429658, "MAYZENT": 92.35270030804791, "MEPOLIZUMAB": 0.8268543172045479, "METHOTREXATE": 0.5252704530870106, "OCRELIZUMAB": 3.401730020793124, "OCREVUS": 38.058270279091005, "PEGASYS": 0.7309473194571938, "PEGINTRON": 0.3221087917761501, "PLEGRIDY": 42.04423185214561, "PREGABALIN": 2.3585633878067807, "REBIF": 25.67628620896644, "REMICADE": 2.0102165199118067, "RITUXIMAB": 1.3811560552627753, "SHINGRIX": 0.2966807357081974, "SIMPONI": 4.117131880928898, "SPIKEVAX": 0.3734578060988067, "STELARA": 2.116812412680672, "TASIGNA": 1.001037494463915, "TECFIDERA": 46.771396749336944, "TERIFLUNOMIDE": 35.87273619557571, "TOVIAZ": 6.419184797446486, "TOZINAMERAN": 0.7865431742014661, "TREMFYA": 2.071140049646887, "TWINRIX": 15.36636396973925, "TYSABRI": 24.32487228764193, "VAXZEVRIA": 0.2105181767974761, "VIAGRA": 4.001563035040417, "XELJANZ": 0.7735612147599011, "XOLAIR": 1.542536203712496, "ZINBRYTA": 20.702358230624483, "ZOSTAVAX": 0.6645520885610613, "ZYPREXA": 0.2222122689114266, "null": 0.4357833410174464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7799.json
index fd63b73bc6e..f826054f3c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7799.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7799.json
@@ -1 +1 @@
-{"null": 2.094421477818836}
\ No newline at end of file
+{"AUBAGIO": 36.98567155641817, "SPIKEVAX": 1.4353749071555375}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/78.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/78.json
index c4de1c150b1..7b3aa3a9d26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/78.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/78.json
@@ -1 +1 @@
-{"null": 2.23656444563837}
\ No newline at end of file
+{"null": 1.4308638089904002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/780.json
index b4f4ab93d24..b24eef9cde7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/780.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/780.json
@@ -1 +1 @@
-{"FENTANYL": 49.41700036750469, "null": 1.2695044214265356}
\ No newline at end of file
+{"null": 1.5412770414629104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7800.json
index ba7f1ae46ee..c6c6cceccb6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7800.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7800.json
@@ -1 +1 @@
-{"null": 3.312671505069676}
\ No newline at end of file
+{"AIMOVIG": 0.2543859080263927, "ALEMTUZUMAB": 14.20534678057345, "AUBAGIO": 442.2153452914684, "AVONEX": 48.296963572785415, "BETAFERON": 83.12951191182691, "BUPIVACAINE": 3.1634542300447297, "CLADRIBINE": 15.468165152158816, "COMIRNATY": 0.3607647982045967, "COSENTYX": 0.4347750188033155, "CYMBALTA": 0.1569982581658432, "FAMPRIDINE": 18.416880905597733, "FAMPYRA": 65.04560947905242, "FINGOLIMOD": 43.94406459061196, "GILENYA": 50.62157833187744, "KESIMPTA": 86.02330080684595, "LEMTRADA": 56.59241725987772, "MAVENCLAD": 174.77523083919445, "MODERNA": 0.3726191580698054, "OCRELIZUMAB": 0.7215917584827766, "OCREVUS": 29.09856964033237, "PLEGRIDY": 67.4278312661942, "REBIF": 23.640733938495227, "RITUXIMAB": 0.8958530168365063, "SHINGRIX": 0.4834589868700816, "SPIKEVAX": 0.1710150745897737, "TECFIDERA": 48.757346912509696, "TERIFLUNOMIDE": 74.31171249524328, "TOZINAMERAN": 0.3108296234861626, "TYSABRI": 65.17285575728312, "VAXZEVRIA": 0.1316985403973656, "ZINBRYTA": 147.53093478950782, "null": 0.178191599263209}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7801.json
index 870f14fb7cb..4aba63e57db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7801.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7801.json
@@ -1 +1 @@
-{"BUSULFAN": 97.51845121984452, "CYTARABINE": 34.90311658194775, "METHOTREXATE": 11.687368563479223}
\ No newline at end of file
+{"ENBREL": 30.94627366493956, "null": 0.8893525261632298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7802.json
index 0a333fadc16..d4e81a7721c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7802.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7802.json
@@ -1 +1 @@
-{"AMIKACIN": 17.30427004045918, "ARIPIPRAZOLE": 4.487499886645684, "CASPOFUNGIN": 29.846691693096474, "CICLOSPORIN": 4.516795844731306, "CIMZIA": 2.172062824306629, "COSENTYX": 2.282523152190114, "DEXAMETHASONE": 3.197194006509636, "EYLEA": 7.1067944322582095, "GARDASIL": 1.765424541168829, "HIZENTRA": 9.918279237222045, "JARDIANCE": 2.179778881654666, "PEGASYS": 1.0614371607593909, "PEGINTRON": 2.99569724684197, "STELARA": 5.952111671836829, "XOLAIR": 2.333086403524534}
\ No newline at end of file
+{"APIDRA": 118.02402236528296, "EYLEA": 391.0617514444264, "IKERVIS": 267.97990693400607, "LANTUS": 35.31298796091853, "NOVORAPID": 16.01032268205924, "TOUJEO": 36.7594532910498, "null": 0.4045314058016086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7803.json
index 6bf43c57d9d..7cdd12c96c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7803.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7803.json
@@ -1 +1 @@
-{"CICLOSPORIN": 4.707114622703459, "CYTARABINE": 24.48153756135591, "ROACTEMRA": 21.4324120417734}
\ No newline at end of file
+{"ABACAVIR": 9.396463745113849, "ADALIMUMAB": 1.1404244364315446, "AMIKACIN": 9.484347282901172, "AMINOSALICYLIC": 3.427056268840273, "ANAKINRA": 11.08934088835412, "AVAPRITINIB": 221.49405833462865, "AZATHIOPRINE": 2.308846175579837, "BEVACIZUMAB": 2.8189290424931954, "BRIVARACETAM": 383.9333592629885, "BRIVIACT": 61.94275572432765, "CAELYX": 7.648590483363011, "CANNABIDIOL": 261.95180239719457, "CASPOFUNGIN": 6.244033658629087, "CIDOFOVIR": 60.847392246304615, "COMBIVIR": 8.138254552665765, "DAPTOMYCIN": 15.890956090397513, "DEXAMETHASONE": 4.611006668846552, "ELTROMBOPAG": 74.46096596188573, "ENTECAVIR": 19.48396269195553, "FENTANYL": 2.276526031809275, "FYCOMPA": 81.50660345662867, "HUMAN": 11.0300676048815, "HYDROCORTISONE": 4.785969055520449, "KEPPRA": 32.053076223543805, "LACOSAMIDE": 290.1051023038506, "LAMIVUDINE": 6.862826082977011, "LEVETIRACETAM": 108.75641881042888, "MIDAZOLAM": 10.668913265310731, "PERAMPANEL": 151.4527106111148, "STRIBILD": 1.2900423396291385, "VIMPAT": 6.261785591153815, "VORICONAZOLE": 4.717739569623929, "ZONISAMIDE": 47.622253705920464, "null": 0.1510851577754942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7804.json
index 31247a5e6ed..ffc7b9dc681 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7804.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7804.json
@@ -1 +1 @@
-{"GARDASIL": 6.955982603534175}
\ No newline at end of file
+{"COMIRNATY": 2.2347215013396338, "ENBREL": 21.0934345137957, "SPIKEVAX": 2.150816462113289, "TOZINAMERAN": 3.776242766753983, "VAXZEVRIA": 0.678889388050906, "null": 0.1494934628969998}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7805.json
index 7af480e9791..a5dff31f166 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7805.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7805.json
@@ -1 +1 @@
-{"ABILIFY": 1.5433146874161123, "ACLASTA": 6.108713715741348, "ADEMPAS": 1.9666597945820896, "AIMOVIG": 7.349167480154613, "ALEMTUZUMAB": 1.0522219596843554, "APIDRA": 1.870693908546415, "ARANESP": 14.698714259418422, "ARIPIPRAZOLE": 1.0358325156016897, "AUBAGIO": 4.011606811415761, "AVONEX": 5.874309791535641, "BENLYSTA": 3.845896128641382, "BIKTARVY": 1.174335865534843, "BOSULIF": 2.7406052831799, "BOTULINUM": 3.515337933710041, "BRIVIACT": 1.663206287304493, "BYDUREON": 2.550168436074544, "BYETTA": 2.175542803836019, "C1": 20.750398350407863, "CANNABIDIOL": 2.7654569226944017, "CAPECITABINE": 1.2301012541748773, "CHAMPIX": 3.944521303528497, "CIMZIA": 2.6307595387224576, "CINRYZE": 6.568027563436781, "CLOPIDOGREL": 1.2103465672769536, "COSENTYX": 2.9579064394750483, "CYMBALTA": 1.2293271708107187, "DARBEPOETIN": 20.310307451906084, "ENBREL": 1.7199094880333914, "ENTYVIO": 3.0583077692666296, "ESBRIET": 1.068730690571267, "EXFORGE": 1.630385120592809, "FAMPYRA": 2.04133006887499, "FASENRA": 1.6079259069216625, "FIRDAPSE": 1.6563577601963193, "FLUTICASONE": 11.498815424227177, "FULVESTRANT": 1.2063938889646906, "GARDASIL": 1.944713157190328, "GILENYA": 9.27220948299212, "HIZENTRA": 1.2753216420644582, "HUMALOG": 4.736833351745925, "HUMIRA": 4.363558512458579, "I": 119.16129990853575, "IBRANCE": 2.671666498681022, "INFLECTRA": 5.449502028288671, "INSULIN": 6.062002751662191, "JANUMET": 1.2292534064292102, "KEPPRA": 1.6055692813658151, "LANTUS": 1.7282161141482, "LATUDA": 2.730203913937683, "LEFLUNOMIDE": 1.3754113454045682, "LEVEMIR": 1.2811428413108836, "LYRICA": 1.1374877692522012, "MAVENCLAD": 1.7530908405875645, "MEPOLIZUMAB": 4.572449274301095, "METHOTREXATE": 2.025588327997877, "NAGLAZYME": 1.1397446289223303, "NUCALA": 1.1419714204717997, "OMALIZUMAB": 4.224858086692782, "OPTIMARK": 1.857307982392227, "PLEGRIDY": 3.996781270177048, "PROPRANOLOL": 2.390426165053328, "RASILEZ": 1.1022643251556912, "REMSIMA": 19.057788030558893, "RINVOQ": 1.3614683585053764, "RUCONEST": 5.023775538339215, "SILDENAFIL": 2.6225849839214184, "SIMPONI": 1.3683844157727358, "SKYRIZI": 2.8421787837467627, "SOLIRIS": 1.4635023552440365, "SOMATROPIN": 2.4625437485970263, "STELARA": 1.765206845471582, "SUBOXONE": 1.0969550267726025, "TOUJEO": 2.5029855386445985, "TREMFYA": 1.057209800340098, "TRULICITY": 1.4912090823450772, "VIAGRA": 2.360335735435324, "VIMPAT": 1.3813468186777986, "XELJANZ": 4.406089547947764, "XOLAIR": 2.065344037271125, "XYREM": 6.489671831261996, "ZOSTAVAX": 2.822684838816258, "null": 1.150400880279931}
\ No newline at end of file
+{"COMIRNATY": 2.527825960790225, "SPIKEVAX": 2.5616964390696686, "VAXZEVRIA": 1.198783819864249}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7806.json
index 6333e734b41..a42c71ba687 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7806.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7806.json
@@ -1 +1 @@
-{"ARAVA": 4.354303970139391}
\ No newline at end of file
+{"COMIRNATY": 4.7748907395988, "TOZINAMERAN": 6.540735860983297, "null": 0.1149648938434856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7807.json
index 0948234c833..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7807.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7807.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 2.489382802336752, "CARBIDOPA": 13.145547690615048, "DENOSUMAB": 22.053231000965635, "FENTANYL": 13.260817571646328, "HUMAN": 4.837802516709411, "KEYTRUDA": 3.0530301926649046, "LEVETIRACETAM": 1.4752944519727087, "MIDAZOLAM": 11.479068475452708, "SUFENTANIL": 34.463940685367675, "VOTRIENT": 1.4137097762527495, "null": 2.747675599450008}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7808.json
index c4b1e85b1e2..f632dcacbc9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7808.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7808.json
@@ -1 +1 @@
-{"ATRIPLA": 12.024331876018335, "BONVIVA": 74.54364290886284, "CIMZIA": 6.888361547584975, "ELIQUIS": 2.894468028928482, "ENBREL": 15.262648569195054, "EVENITY": 17.55122792646365, "EVISTA": 20.148786191374477, "LOPINAVIR": 37.52594035680793, "ROACTEMRA": 5.089898321611462, "STRIBILD": 8.399935519389151, "TRUVADA": 2.8758305028396043, "XELJANZ": 3.172593327144537}
\ No newline at end of file
+{"COMIRNATY": 0.0793703211509465, "MIDAZOLAM": 18.370669769459653, "MMRVAXPRO": 21.46837729829788, "VAXZEVRIA": 0.0741044392990987, "null": 10.480857148885669}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7809.json
index b67e9c1f633..cc820208fa6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7809.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7809.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 45.169186461719256}
\ No newline at end of file
+{"MMRVAXPRO": 100.51277911411076, "null": 2.626349205883657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/781.json
index 49497a2bc16..3116ddda27f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/781.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/781.json
@@ -1 +1 @@
-{"null": 1.906036144418784}
\ No newline at end of file
+{"AMIKACIN": 38.4740518413227, "CLOPIDOGREL": 2.0848164222004635, "CYMBALTA": 2.1280490366634504, "ELIQUIS": 1.1383813671850544, "XARELTO": 13.327564404483804, "null": 5.763477085029999}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7810.json
index d6f7a8baf4a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7810.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7810.json
@@ -1 +1 @@
-{"ZOSTAVAX": 9.679072103604822, "null": 1.848783223923668}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7811.json
index 52cf14f6238..a24fc24e095 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7811.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7811.json
@@ -1 +1 @@
-{"ARAVA": 1.0569061648802316, "DEXAMETHASONE": 3.2539639021004136, "FENTANYL": 3.0890755972522137, "LEVOFLOXACIN": 1.6686077288388, "SYNAGIS": 9.228466856804358, "TOZINAMERAN": 1.0449287411523451, "XOLAIR": 5.414520676846805, "null": 2.8247031944229346}
\ No newline at end of file
+{"null": 1.2565735543080117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7812.json
index cba75803e9d..41651713749 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7812.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7812.json
@@ -1 +1 @@
-{"null": 1.200916273065125}
\ No newline at end of file
+{"null": 0.9124907343506812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7813.json
index 492ff4f3ad4..8b5194a1f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7813.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7813.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 52.51102740603742, "MYCOPHENOLATE": 65.07194970070154}
\ No newline at end of file
+{"LEMTRADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7814.json
index 814ed67cce0..4ab2227c14d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7814.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7814.json
@@ -1 +1 @@
-{"ABILIFY": 111.7568272976294}
\ No newline at end of file
+{"CANAKINUMAB": 1507.303276494352, "PEGASYS": 4.729710007216791, "PEGINTRON": 8.03650631955333, "null": 0.6587645351547899}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7815.json
index ad213b6a61c..edf24a1aad3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7815.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7815.json
@@ -1 +1 @@
-{"ABILIFY": 2.7600823538025265, "ARIPIPRAZOLE": 1.473254967285407, "CLOPIDOGREL": 1.012383274752755, "CYMBALTA": 1.4928349079990622, "FENTANYL": 2.546429465014924, "IBUPROFEN": 4.001873510360035, "JARDIANCE": 1.0051249586648805, "KEPPRA": 3.6237758844165184, "LACOSAMIDE": 4.743530213663774, "LEVETIRACETAM": 2.8858574826976136, "LEVOFLOXACIN": 1.3765219001137097, "MIDAZOLAM": 3.630988388418596, "OLANZAPINE": 3.687672587905474, "VFEND": 2.255989659425053, "ZYPADHERA": 10.97224510541739, "ZYPREXA": 4.414903719105964, "null": 3.724517642424073}
\ No newline at end of file
+{"ABACAVIR": 1.7750510496386822, "ARAVA": 0.0919323301176213, "ATRIPLA": 0.6836521372024645, "BENLYSTA": 1.9050510602455293, "BIKTARVY": 3.983226531210247, "BUDESONIDE": 1.1925410511310195, "BYDUREON": 1.1409384560317457, "CELLCEPT": 1.288115151552818, "CICLOSPORIN": 0.888720794815202, "CIMZIA": 0.6622281206529003, "COMIRNATY": 0.5272543352669535, "COSENTYX": 2.011480610175076, "CRIXIVAN": 5.7329972241464535, "CYMBALTA": 4.958493366109337, "DEXAMETHASONE": 1.5022359235702525, "DULOXETINE": 2.7639322609405164, "ELIQUIS": 0.2271884715563309, "ENBREL": 0.8404071486182146, "ESOMEPRAZOLE": 4.087201747226432, "FAMPYRA": 2.6581365942979693, "FORSTEO": 1.4845624434475846, "FORXIGA": 2.7264548077039303, "GARDASIL": 1.0460118393032702, "HUMALOG": 0.7838634544957334, "IBRANCE": 0.5102864687761196, "INLYTA": 1.335978914773854, "JANUVIA": 0.7998002937679165, "JARDIANCE": 2.279003948361765, "KALETRA": 1.822170607790308, "KEPPRA": 0.8089058995931726, "KEYTRUDA": 0.7581334170709105, "LANTUS": 0.815445423175542, "LEVOFLOXACIN": 1.1350671413757754, "LYRICA": 1.1587530320721728, "OPTIMARK": 2.7015857282212723, "PANTOPRAZOLE": 2.109019253649244, "PEGASYS": 1.6106667703992898, "PEGINTRON": 2.279827764167504, "SIMPONI": 0.5327964121002116, "SPIKEVAX": 0.3392432621765572, "SUTENT": 0.6361241183262213, "TOZINAMERAN": 0.8696410387159008, "VAXZEVRIA": 0.2375234971062393, "XELJANZ": 0.7129788368086956, "XOLAIR": 0.6900469438555589, "XTANDI": 1.9979912316713373, "ZOSTAVAX": 1.577592488958139, "ZYPREXA": 0.575748926764086, "null": 1.4402934444041815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7816.json
index 030006990ba..ace0291cabf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7816.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7816.json
@@ -1 +1 @@
-{"DOCETAXEL": 9.68083023843458, "KEYTRUDA": 3.047388383134796, "null": 2.973498864588808}
\ No newline at end of file
+{"JARDIANCE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7817.json
index e2e61b2f0a9..5448684f1fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7817.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7817.json
@@ -1 +1 @@
-{"null": 1.1570402041494208}
\ No newline at end of file
+{"AFINITOR": 1.799275043461367, "AMINOSALICYLIC": 2.82479437504366, "BRINTELLIX": 1.6283565141440626, "CEFUROXIME": 59.08739854093133, "COMIRNATY": 1.70077744042906, "CYMBALTA": 0.8353171776952198, "EVEROLIMUS": 7.934051166488537, "FORSTEO": 0.8042203582868258, "GARDASIL": 2.450452707286093, "LEVOFLOXACIN": 1.7121440290532453, "LYRICA": 2.344325807211219, "MODERNA": 2.694911661188221, "OLANZAPINE": 2.186047644428774, "OPTIMARK": 2.1274734560659434, "SPIKEVAX": 0.9888987516882825, "TAMIFLU": 1.509956106863226, "TOZINAMERAN": 1.2981971149742184, "VAXZEVRIA": 0.6482360345918333, "XOLAIR": 0.8988003839863045, "ZYPREXA": 1.2503698277264232, "null": 1.6345049208822722}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7818.json
index 4e6e6a88c8d..2aae4523c7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7818.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7818.json
@@ -1 +1 @@
-{"null": 2.5173319162917376}
\ No newline at end of file
+{"ABILIFY": 3.153394120556986, "COMIRNATY": 0.9320622622283524, "GARDASIL": 2.1030527772341507, "LEVOFLOXACIN": 1.9958934959731112, "OPTIMARK": 57.46387176007076, "PEGASYS": 0.9004080377370248, "SPIKEVAX": 0.258610972692933, "SPINRAZA": 22.321433396426976, "TOZINAMERAN": 0.4082797674947609, "VAXZEVRIA": 0.4781313888832464, "null": 1.2717331584485652}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7819.json
index 2c66c6bf5d9..b943dde8759 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7819.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7819.json
@@ -1 +1 @@
-{"APIXABAN": 6.700008004897519, "APROVEL": 2.666652773030102, "ARIXTRA": 13.267803265070238, "AVASTIN": 1.5469659255736543, "BRILIQUE": 7.219619929664407, "CARBIDOPA": 5.683686776887623, "CLOPIDOGREL": 13.206684871597894, "DULOXETINE": 1.319328106545707, "EFIENT": 16.704334966114562, "ELIQUIS": 13.096167844270582, "ENOXAPARIN": 3.862276025776406, "EVENITY": 7.950975202226571, "EYLEA": 1.0903478408847975, "HARVONI": 4.102340497844847, "INTRONA": 4.523764780366626, "JAKAVI": 1.5501683680300056, "LIXIANA": 7.023625928807696, "NOVOSEVEN": 5.5505605038922665, "NPLATE": 1.7140332723567264, "PEGASYS": 1.6407999048788695, "PEGINTRON": 3.3067832041759617, "PLAVIX": 12.19462490815097, "PRADAXA": 8.723218035085091, "REMICADE": 3.1318327198049123, "SILDENAFIL": 4.296289355427225, "TICAGRELOR": 11.808347174243016, "VIAGRA": 1.176577487644421, "VOTRIENT": 1.2902169151342056, "XARELTO": 8.105009312477103, "null": 1.20587497929925}
\ No newline at end of file
+{"COMIRNATY": 1.8135376211984016, "LEVOFLOXACIN": 2.2210035449786303, "NILEMDO": 632.4611504205525, "SHINGRIX": 1.7074494791045156, "SPIKEVAX": 1.8022908014001124, "TOZINAMERAN": 0.5908869170662581, "VAXZEVRIA": 1.2249344472411654, "null": 1.100520159872136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/782.json
index f8786400b77..604df3f8d8f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/782.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/782.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 6.514533841453183, "COMIRNATY": 1.0761072116110186, "CYMBALTA": 1.039260151659948, "FENTANYL": 4.7465139538698695, "GARDASIL": 31.91917461103637, "LEVETIRACETAM": 2.060579054294554, "MIDAZOLAM": 8.422349659448837, "OLANZAPINE": 7.107026321384545, "TOZINAMERAN": 1.8950767689891928, "ZYPREXA": 2.2989511702555423}
\ No newline at end of file
+{"null": 3.440052412526468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7820.json
index 0be04bc7bca..405194b8a78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7820.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7820.json
@@ -1 +1 @@
-{"ELIQUIS": 8.440257728738448, "null": 1.510335707315242}
\ No newline at end of file
+{"ABILIFY": 2.9456177657334197, "ADALIMUMAB": 0.2961080124133082, "BYDUREON": 5.09456708479454, "CICLOSPORIN": 0.7497744213653748, "CLOPIDOGREL": 0.7923975869031503, "COMIRNATY": 0.4083050118692541, "CYMBALTA": 0.771243715608952, "ELIQUIS": 0.4326759453142333, "FASLODEX": 2.2124704111162545, "GARDASIL": 1.426763537279278, "HUMALOG": 1.2346980506121132, "IBRANCE": 0.7746940519149846, "KEYTRUDA": 0.8930188321782756, "LANTUS": 0.7945906688634319, "LYRICA": 4.391432663931055, "OLANZAPINE": 1.5066254230099425, "OPTIMARK": 1.780174623490422, "PEGASYS": 0.5742291590716295, "PLAVIX": 0.7845235316638457, "SPIKEVAX": 0.2564341808042413, "SUTENT": 0.323802502140982, "TOZINAMERAN": 1.235462599636499, "VAXZEVRIA": 0.2211144715301421, "XELJANZ": 0.9560110367680776, "ZOSTAVAX": 0.9095398588453252, "null": 1.996016912858624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7821.json
index 9494d09fc84..c1bbb4b698c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7821.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7821.json
@@ -1 +1 @@
-{"null": 1.565884622223341}
\ No newline at end of file
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7822.json
index cece2d7511f..a3bfc9f841c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7822.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7822.json
@@ -1 +1 @@
-{"null": 1.6801798214955463}
\ No newline at end of file
+{"ROTATEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7823.json
index 5e66c5600de..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7823.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7823.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2280637795023353, "DOCETAXEL": 36.335822128779775, "ELIQUIS": 1.7425691749771912, "NOVOSEVEN": 109.26752282674882, "VAXZEVRIA": 1.0476913324478587}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7824.json
index 4c2bfa22c4b..9aaf1222ee2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7824.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7824.json
@@ -1 +1 @@
-{"null": 1.999426350398048}
\ No newline at end of file
+{"null": 1.813399224492927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7825.json
index 5e5a53e36bd..987b462bad6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7825.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7825.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.6167135403996271, "AMINOSALICYLIC": 11.514146684966835, "BENLYSTA": 5.275554677179038, "CELLCEPT": 2.3128326800366144, "CICLOSPORIN": 3.410559908613433, "CIMZIA": 4.195888796306615, "COSENTYX": 4.777035945422512, "ENTYVIO": 3.282786454231986, "HUMIRA": 5.361809609389688, "JARDIANCE": 1.3699505352760235, "KETOCONAZOLE": 74.53458561849743, "LEVOFLOXACIN": 2.379752553670076, "PEGASYS": 2.2214322708335352, "RINVOQ": 4.220845161687265, "ROACTEMRA": 8.389742910958251, "SIMPONI": 5.856406556078571, "STELARA": 5.217637143572428, "XELJANZ": 1.8628020721633056, "ZOSTAVAX": 1.6315487642581068}
\ No newline at end of file
+{"BYDUREON": 3.9753474819371175, "CICLOSPORIN": 1.697469408180187, "COMIRNATY": 1.1879143442770064, "CYMBALTA": 0.9909912690701178, "ELIQUIS": 0.3436462930135847, "FAMPYRA": 2.5036250952349213, "GARDASIL": 1.801750209135023, "HYDROCORTISONE": 4.276158889589354, "MODERNA": 1.8291874652627385, "OCRELIZUMAB": 7.347258373151082, "OPTIMARK": 3.4142423782617337, "PLAVIX": 0.4916667869042051, "SHINGRIX": 1.0166364233356933, "SPIKEVAX": 1.0723974082833942, "STELARA": 0.7809910030536714, "SUTENT": 0.2912884322944455, "TOZINAMERAN": 4.273675513577593, "VAXZEVRIA": 5.950174438573368, "null": 0.2838918657824282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7826.json
index a92ebfa8528..32a30f4ca84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7826.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7826.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 11.839374203600183, "null": 1.616442462880516}
\ No newline at end of file
+{"OPTIMARK": 190.51015348922263, "null": 1.0088296720616217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7827.json
index 833082d00ef..83c49d61f11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7827.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7827.json
@@ -1 +1 @@
-{"BRILIQUE": 13.875458546306543, "BRINTELLIX": 5.788091291239834, "CLOPIDOGREL": 15.054068821658628, "EFIENT": 25.52917955779758, "ELIQUIS": 7.735414207091756, "ENOXAPARIN": 15.118830384412425, "LIXIANA": 7.930173410645819, "PLAVIX": 10.83445632794738, "XARELTO": 12.316947880461283, "null": 2.3739751561721523}
\ No newline at end of file
+{"NEULASTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7828.json
index 8fea981f33b..19f95bdecf7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7828.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7828.json
@@ -1 +1 @@
-{"null": 1.3134087338085194}
\ No newline at end of file
+{"ABACAVIR": 3.1421042455548305, "ADVATE": 168.5913638164659, "ARIXTRA": 77.7148033002511, "BRILIQUE": 4.545328065823463, "CLOPIDOGREL": 5.118803367750012, "COMIRNATY": 0.0672864905247523, "ELIQUIS": 13.854902500290732, "EMICIZUMAB": 222.32659432783367, "ENOXAPARIN": 17.843137279145306, "HEMLIBRA": 368.8851761018944, "KOVALTRY": 231.06293822332853, "LIXIANA": 8.788041150014225, "NOVOSEVEN": 35.37199944726619, "PLAVIX": 9.419930302962554, "VAXZEVRIA": 0.0439660826941949, "XARELTO": 9.088419294248208, "null": 2.1911934146172505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7829.json
index aae0c4c05d8..d6dbb275e79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7829.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7829.json
@@ -1 +1 @@
-{"null": 1.2897868525631466}
\ No newline at end of file
+{"null": 0.821531774086839}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/783.json
index 5fe44de45b8..de33cf8e420 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/783.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/783.json
@@ -1 +1 @@
-{"EMTRIVA": 194.14946612919385, "GARDASIL": 23.450875887580985, "HUMALOG": 3.8413768636772736, "TELMISARTAN": 85.42130020171288, "ZOSTAVAX": 5.283435771539493}
\ No newline at end of file
+{"null": 1.2678387061803291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7830.json
index db8501bd686..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7830.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7830.json
@@ -1 +1 @@
-{"APIXABAN": 1.079209890998773, "ARIXTRA": 28.4468661081193, "BRILIQUE": 18.47948232333048, "CLOPIDOGREL": 12.624267404495336, "CYTARABINE": 1.2971085050065732, "DEFITELIO": 11.830100610499509, "EFIENT": 25.389920420506563, "ELIQUIS": 19.38551091233124, "ENOXAPARIN": 10.969171664236264, "EPIVIR": 2.282145280074888, "ESOMEPRAZOLE": 1.6688727186566743, "EVENITY": 3.341747108730501, "EXJADE": 1.1840503732316874, "GLIVEC": 4.243015128614345, "HEMLIBRA": 5.7370897854496885, "INFANRIX": 2.6638136590822263, "JAKAVI": 2.194840061450238, "LIXIANA": 9.90758528625753, "NPLATE": 3.1179691023027325, "PLAVIX": 30.88754166314978, "PRADAXA": 10.348954693550738, "PRASUGREL": 15.92770024575651, "SOVALDI": 1.961300060398737, "SPRYCEL": 3.095648272598268, "TASIGNA": 1.1174180884742535, "TICAGRELOR": 4.562433482018913, "VIDAZA": 28.560072759698897, "XARELTO": 12.921724845679815, "XOFIGO": 3.644857750081609, "XTANDI": 1.6045938205475738, "null": 1.8453889025698904}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7831.json
index 762548caaaa..7a8bff3e56a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7831.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7831.json
@@ -1 +1 @@
-{"null": 2.6663739977605343}
\ No newline at end of file
+{"ABATACEPT": 55.342635451091255, "ACETAMINOPHEN": 101.14402644684608, "ADALIMUMAB": 8.775799809338043, "AMINOSALICYLIC": 3.260409262178809, "APREMILAST": 21.68880441626898, "APREPITANT": 10.68946862316932, "ARAVA": 11.258889709866033, "CHLORHEXIDINE": 158.93044170022665, "CIMZIA": 53.27707227251906, "COMIRNATY": 0.0718712756790794, "COSENTYX": 4.39437271694604, "ERELZI": 12.94164204648183, "OLANZAPINE": 0.577796455457594, "PLAVIX": 0.4038046682592456, "RINVOQ": 1.1935127905150251, "RITUXIMAB": 2.307569824353733, "SPIKEVAX": 0.0588385989875933, "STELARA": 0.3281234168800633, "TOZINAMERAN": 0.4082776008037836, "VAXZEVRIA": 0.1276712560379764, "VIAGRA": 1.236741950004642, "null": 0.1801553326396037}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7832.json
index e2ce77c1d0f..a3698e5651d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7832.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7832.json
@@ -1 +1 @@
-{"ARIXTRA": 37.39592895397138, "BRILIQUE": 6.94048916646107, "CLOPIDOGREL": 11.667877528911731, "CYTARABINE": 2.442995380310994, "ELIQUIS": 15.214601432025654, "ENOXAPARIN": 12.60754683840096, "PLAVIX": 15.223391912779832, "XARELTO": 8.478360325915741, "null": 2.301758699086143}
\ No newline at end of file
+{"COMIRNATY": 0.2380385844427478, "TESTOSTERONE": 194.53045341531097, "VAXZEVRIA": 0.5711392150008487, "null": 0.5307580426417736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7833.json
index f4e74958daa..efa6f15ef79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7833.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7833.json
@@ -1 +1 @@
-{"null": 1.5276271081251525}
\ No newline at end of file
+{"COMIRNATY": 0.112615036966464, "null": 3.154694989502248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7834.json
index 06bb368801a..c445cff345c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7834.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7834.json
@@ -1 +1 @@
-{"null": 1.872168776398728}
\ No newline at end of file
+{"COMIRNATY": 1.281694302454726, "SPIKEVAX": 0.927794179645422, "VAXZEVRIA": 0.5752979924880168, "null": 0.915549125083666}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7835.json
index 2f0a79a60ea..3c937d75dc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7835.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7835.json
@@ -1 +1 @@
-{"MMRVAXPRO": 33.520679541267015, "null": 2.278004847841669}
\ No newline at end of file
+{"ZOSTAVAX": 218.52821849535184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7836.json
index 3c599382332..d274bd60c50 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7836.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7836.json
@@ -1 +1 @@
-{"AVASTIN": 17.90211670381095, "STELARA": 6.204517686920676, "STIVARGA": 5.516226425844927, "TOVIAZ": 13.920481368522324, "null": 1.7990371532754816}
\ No newline at end of file
+{"ABILIFY": 4.700718668441071, "ARIPIPRAZOLE": 8.692299447812257, "BETAFERON": 2.472485330421788, "BRIDION": 7.333131929815521, "BRINTELLIX": 0.7931742123596315, "BUDESONIDE": 0.5739975095214044, "BUPIVACAINE": 2.2003652558753712, "BUPRENORPHINE": 1.267437300777428, "CARBIDOPA": 19.89832495979181, "CICLOSPORIN": 0.6368421949923408, "COMIRNATY": 0.3346293117633804, "COMTAN": 33.26051489828492, "CYMBALTA": 1.0523150978926925, "DEXAMETHASONE": 0.4781776773816443, "DULOXETINE": 2.3996283696031946, "ELIQUIS": 0.144167058872768, "ENTACAPONE": 29.85303263033005, "EXFORGE": 1.21196761463041, "FENTANYL": 5.945924163547891, "FORSTEO": 1.292572070908749, "GARDASIL": 2.295670642580961, "IBUPROFEN": 0.8339515604683042, "INFANRIX": 3.3394778109955543, "KEPPRA": 0.3747876439165339, "LANTUS": 0.5416186251575624, "LATUDA": 6.943846111455374, "LEVETIRACETAM": 1.4018862496585969, "LEVODOPA": 16.405095550951703, "LEVOFLOXACIN": 0.9482523813739346, "MENVEO": 7.146836995226273, "MIDAZOLAM": 5.451503488663443, "MMRVAXPRO": 0.5870213363054697, "NIMENRIX": 1.6142822405667347, "OLANZAPINE": 19.996983856505988, "OPTIMARK": 1.035957983855722, "PALIPERIDONE": 33.29453172440556, "PREGABALIN": 1.904797265858733, "RENVELA": 157.05964573374231, "RISPERIDONE": 21.58596416363122, "SIFROL": 4.681903116351543, "SIMPONI": 0.5213383017889672, "SPIKEVAX": 0.4409657905575652, "STALEVO": 16.086162379776695, "SYCREST": 13.567981271452318, "TOZINAMERAN": 0.3056142706324726, "VAXZEVRIA": 0.2706710746777614, "ZONISAMIDE": 14.557648724337986, "ZYPADHERA": 5.275722377631711, "ZYPREXA": 11.520855826122212, "null": 2.367063371000661}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7837.json
index 9a53d5479b7..3176aa32719 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7837.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7837.json
@@ -1 +1 @@
-{"COMIRNATY": 1.407999327355998}
\ No newline at end of file
+{"COMIRNATY": 0.274860157297341, "ELIQUIS": 2.36529388131708, "LEVOFLOXACIN": 4.858548004722016, "PLAVIX": 1.4173794971670892, "SIMPONI": 1.833235330560809, "SPIKEVAX": 0.0989124806750609, "TOZINAMERAN": 1.142049707424382, "VAXZEVRIA": 0.2978909434506535, "VIAGRA": 3.566568541899536, "XELJANZ": 4.2392293976289785, "null": 2.274232662329611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7838.json
index 141d1739324..9c3977cd293 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7838.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7838.json
@@ -1 +1 @@
-{"AVASTIN": 13.88802282469683, "BEOVU": 388.3549573386, "BEVACIZUMAB": 16.728730146852527, "BRAFTOVI": 32.242377527463496, "BROLUCIZUMAB": 590.32492324649, "EYLEA": 264.2845267900933, "JETREA": 2367.188877863163}
\ No newline at end of file
+{"ABACAVIR": 0.0729163872229538, "ABASAGLAR": 1.2865933745190488, "ABATACEPT": 1.2573827308131762, "ABILIFY": 1.0777812186087128, "ACTOS": 0.8099219143841857, "ADALIMUMAB": 0.334727338405298, "ADCIRCA": 0.4051299362266435, "ADEMPAS": 0.6988223225791518, "ADENURIC": 1.0204125602914889, "AERIUS": 1.652387184686767, "AFINITOR": 0.4878585382269849, "AIMOVIG": 2.9959134966343988, "ALEMTUZUMAB": 0.4486740795574982, "ALOXI": 2.592170907969974, "AMINOSALICYLIC": 0.6245556842441032, "ANORO": 0.5235200030693887, "APIDRA": 0.392692296511442, "APIXABAN": 0.0828006129681438, "APREMILAST": 0.2594169500097649, "APROVEL": 1.7277096404652592, "ARANESP": 0.3384218433914102, "ARAVA": 0.2356239326174916, "ARIPIPRAZOLE": 0.237019072538123, "ATRIPLA": 0.0795416820459376, "AUBAGIO": 1.9202213010278573, "AVAMYS": 0.2271626393738015, "AVANDIA": 0.2592276043705963, "AVASTIN": 0.3018587823969577, "AZATHIOPRINE": 0.7943773534097713, "BEDAQUILINE": 0.4093808545708931, "BENLYSTA": 0.417849602428418, "BETAFERON": 0.979481268300334, "BETMIGA": 0.8728443233449847, "BEVACIZUMAB": 0.1016662867669225, "BEXSERO": 0.9969277305127214, "BIKTARVY": 0.5171680433409162, "BONVIVA": 1.191531526761385, "BOSULIF": 1.111822858195356, "BOSUTINIB": 2.6202544204659968, "BOTULINUM": 0.3158956414143363, "BRAFTOVI": 0.744070620174927, "BRIDION": 0.6381412786718417, "BRILIQUE": 0.1518679743328852, "BRINTELLIX": 1.133967322072806, "BUDESONIDE": 1.4781097209592924, "BUMETANIDE": 0.4467233217522354, "BUPIVACAINE": 3.8022462734058498, "BUPRENORPHINE": 0.6808047851848229, "BYDUREON": 1.238905031116983, "BYETTA": 0.5495943435978567, "CABOMETYX": 0.5968452630956395, "CAPECITABINE": 0.8168660546157098, "CAPSAICIN": 3.6305471763679775, "CELECOXIB": 0.567930739723905, "CELLCEPT": 0.3983466720714583, "CHAMPIX": 0.9997423979710224, "CHOLESTAGEL": 10.699498537987708, "CICLOSPORIN": 0.1202929727266345, "CIMZIA": 0.4760436497240231, "CINACALCET": 1.464199996019566, "CIRCADIN": 0.9185997730637958, "CLOPIDOGREL": 0.4212230367116805, 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"PLEGRIDY": 1.2424163819349718, "PREGABALIN": 0.5420601119481957, "PRIVIGEN": 0.4386804429038013, "PROLIA": 1.012526667319992, "PROTELOS": 2.08928280948712, "RANEXA": 1.4787389138086426, "RASILEZ": 0.6058297655532737, "REBETOL": 0.3806120915555925, "REBIF": 1.3161251766112834, "RELVAR": 3.5753502109139275, "REMICADE": 0.4473848988236861, "REVATIO": 0.296536837726032, "REVINTY": 3.435648955674925, "REVLIMID": 1.690122032214908, "RIBAVIRIN": 0.2110963261419132, "RINVOQ": 0.6052687693613471, "RITUXIMAB": 0.1493508158141973, "ROACTEMRA": 0.3518592925323556, "ROTATEQ": 0.2195307804441083, "RUBRACA": 0.3320975504006476, "RUCONEST": 0.5456747752660049, "RUXOLITINIB": 0.4071047720717727, "RYBELSUS": 1.075285880584593, "SAXENDA": 0.6065018835475531, "SEMAGLUTIDE": 13.696256817795092, "SHINGRIX": 0.504326305964577, "SIFROL": 1.8846854023508504, "SILDENAFIL": 0.4813692422354541, "SIMPONI": 0.3595131937168747, "SOLIRIS": 0.3722238905843886, "SPIKEVAX": 0.8271844521490407, "SPINRAZA": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7839.json
index 4ed874a131a..fc24a035d6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7839.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7839.json
@@ -1 +1 @@
-{"ABILIFY": 3.5263130986333024, "ANTIBIOTICS": 8.95778877498611, "ANTIDEPRESSANTS": 90.91997633762354, "ARIPIPRAZOLE": 1.1197574291210548, "BENZODIAZEPINE": 46.285851496270766, "BENZODIAZEPINES": 86.0903870279452, "BUMETANIDE": 10.415776977316725, "BUPRENORPHINE": 49.51614315149234, "CAFFEINE": 20.207577378223093, "CANNABIDIOL": 7.623263944840117, "FENTANYL": 22.12665117972758, "IBUPROFEN": 2.411940675954169, "LYRICA": 1.9805424553319555, "MIDAZOLAM": 2.8201015187194085, "NOT": 1.9850751974287264, "OLANZAPINE": 1.748204726021444, "OPIOIDS": 107.88791336990845, "OTHER": 37.17149324059408, "POPPERS": 128.38687960271358, "PREGABALIN": 6.817975541651941, "SUBOXONE": 110.84615354209828, "SUBSTANCE": 39.7798324017028, "null": 2.946008259991852}
\ No newline at end of file
+{"ABATACEPT": 14.681150299009458, "ABILIFY": 1.5085680143425997, "ADALIMUMAB": 1.3445843999856313, "ALISKIREN": 52.51727280982763, "ARAVA": 21.03464030881036, "ARIPIPRAZOLE": 1.9460975957091116, "AUBAGIO": 11.39281275245328, "AVONEX": 44.12326087898434, "BETAFERON": 12.427193403691309, "BUDESONIDE": 0.5179383678050525, "BUPIVACAINE": 27.10952948136722, "CELLCEPT": 0.9908272071116272, "CHLORHEXIDINE": 3.536075937963962, "CIMZIA": 3.264402615606399, "COMIRNATY": 0.2220135221211127, "COSENTYX": 0.5556678663315274, "CYMBALTA": 3.453955598142701, "DULOXETINE": 1.6520362396108967, "ESOMEPRAZOLE": 6.058483298729239, "EXFORGE": 1.761300385474899, "FAMPYRA": 32.25305937469725, "FENTANYL": 1.1631996784064962, "GARDASIL": 0.3060358022172593, "HUMALOG": 0.6760286650260497, "IBUPROFEN": 3.649548247837165, "IRBESARTAN": 16.244026615742023, "IRON": 10.15105978166584, "JEVITY": 480.6933859836327, "KEPPRA": 2.56878963787594, "KESIMPTA": 8.92738570125401, "LAMIVUDINE": 4.274967737306327, "LEMTRADA": 5.676457634945312, "LINACLOTIDE": 139.9871035119307, "LYRICA": 4.900513318720591, "MIRABEGRON": 25.36512449452459, "NAGLAZYME": 4.51048855939023, "OXYBUTYNIN": 22.676085063485704, "PLEGRIDY": 4.959433517554394, "RENVELA": 228.3595787715261, "SPIKEVAX": 0.1172782806775681, "TECFIDERA": 27.69113142670508, "TOZINAMERAN": 0.2313025363802217, "VAXZEVRIA": 0.1660797195194823, "null": 0.6702900227770798}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/784.json
index c17830f3ac0..df232646373 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/784.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/784.json
@@ -1 +1 @@
-{"null": 1.9069219250759697}
\ No newline at end of file
+{"ELIQUIS": 9.284369146163844, "PRAXBIND": 1055.8045558201163, "null": 0.9507106027548028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7840.json
index 9903bf49851..2307eef7839 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7840.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7840.json
@@ -1 +1 @@
-{"null": 10.500747080010026}
\ No newline at end of file
+{"AIMOVIG": 1.6134305898887444, "ARAVA": 0.7344125405941132, "AUBAGIO": 1.9263530970531544, "BENRALIZUMAB": 27.95050112906589, "COMIRNATY": 0.573160278930926, "COSENTYX": 3.951236153001663, "CYMBALTA": 0.6459071886927225, "ELIQUIS": 0.4608403679999293, "FORSTEO": 1.2526150139537, "GARDASIL": 0.7626666865498, "HUMALOG": 1.802325095406468, "IBRANCE": 1.4531508191924818, "JARDIANCE": 0.9215016834682198, "LANTUS": 0.5248849842810628, "METHOTREXATE": 3.615715535694063, "PEGASYS": 0.568995682218592, "SPIKEVAX": 0.4486260135710348, "TOZINAMERAN": 1.7234123002977288, "VAXZEVRIA": 0.5442774706234802, "VIAGRA": 2.1026059651859947, "XELJANZ": 4.128929795188474, "ZOSTAVAX": 6.320868330612208, "ZYPREXA": 1.6839782563452708, "null": 1.1248045720325193}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7841.json
index 8af81005887..274afa3b820 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7841.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7841.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 5.169138856838602, "FENTANYL": 51.45855411735601, "SUBOXONE": 9.866326745740343, "null": 6.331813041635209}
\ No newline at end of file
+{"COMIRNATY": 2.233676123513357, "SPIKEVAX": 1.56253836373158, "TOZINAMERAN": 0.7927172306444383, "VAXZEVRIA": 1.7205213065417342, "null": 0.3777701657456583}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7842.json
index 59629462374..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7842.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7842.json
@@ -1 +1 @@
-{"ABILIFY": 287.73242157640954, "APIDRA": 12.853629370532426, "ARIPIPRAZOLE": 12.077966528559744, "BUPRENORPHINE": 16.87081871335275, "GARDASIL": 3.1297115722718534, "PEGINTRON": 4.424820512520087}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7843.json
index 2f3829eb0b5..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7843.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7843.json
@@ -1 +1 @@
-{"BENZODIAZEPINE": 20.759470465012463, "BUPRENORPHINE": 159.01471099110535, "CANNABIDIOL": 89.64153421599345, "FENTANYL": 10.91022446190004, "LYRICA": 3.1043065071430163, "OLANZAPINE": 1.0719822857843726, "PREGABALIN": 7.886679416431402, "SUBOXONE": 8.271369941646682, "null": 4.335625219119751}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7844.json
index 6733bcb0458..a1809598d46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7844.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7844.json
@@ -1 +1 @@
-{"ABILIFY": 21.314506958951185, "ANTIBIOTICS": 64.38417378455624, "BUPRENORPHINE": 14.284913224900988, "CYMBALTA": 1.834643108905696, "DEXAMETHASONE": 5.315356197710391, "KEPPRA": 2.04871700727991, "LEVETIRACETAM": 23.825084299295536, "LEVOFLOXACIN": 6.24603698637604, "OLANZAPINE": 22.212046276659617, "PEGASYS": 1.469597760521188, "ZONISAMIDE": 120.2758147956934, "null": 1.3230306280357491}
\ No newline at end of file
+{"COMIRNATY": 1.5979119899616827, "NIMENRIX": 11.115284585791168, "SPIKEVAX": 2.862222693521663, "TOZINAMERAN": 2.7751797277748764, "VAXZEVRIA": 0.849662087733624, "null": 0.4485443364971145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7845.json
index 6742a5715f7..d296011a6d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7845.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7845.json
@@ -1 +1 @@
-{"null": 5.545978172562894}
\ No newline at end of file
+{"FENTANYL": 314.08475080888263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7846.json
index 947672fe031..4fca415a39d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7846.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7846.json
@@ -1 +1 @@
-{"ABILIFY": 6.061196339269173, "AVANDAMET": 12.478341212113836, "AVANDIA": 16.255661799610106, "ENTRESTO": 9.954921975853894, "MULTAQ": 8.523491933733446, "OLANZAPINE": 14.035715310762845, "TRACLEER": 5.055599712276701, "VAXZEVRIA": 2.194880899304029, "VIAGRA": 2.0580218466295013, "ZYPREXA": 2.0408116117964887, "null": 2.295596642627926}
\ No newline at end of file
+{"ABILIFY": 0.94255026965236, "AIMOVIG": 2.2272331662321707, "ALEMTUZUMAB": 1.8039598153398184, "AUBAGIO": 0.7704825862202794, "BRINTELLIX": 2.171008144194178, "BUPIVACAINE": 3.435916019590448, "CHAMPIX": 0.5448154938623121, "CICLOSPORIN": 0.404950650535036, "CLOPIDOGREL": 0.2775385247903523, "COMIRNATY": 1.3260708656407725, "COSENTYX": 0.9031613443830416, "CYMBALTA": 3.0678312101590786, "ELIQUIS": 0.2763512777912815, "FAMPYRA": 6.344048728152743, "FENTANYL": 1.93195963554455, "FORSTEO": 0.8693618226668925, "GARDASIL": 2.9787755721043467, "HUMALOG": 0.2316255571130349, "HUMIRA": 3.815959290969276, "IBRANCE": 0.4767531860179734, "IBUPROFEN": 0.7072421954026906, "JANUVIA": 2.252211803410609, "KEPPRA": 1.3597470869465442, "KETOCONAZOLE": 16.48986926511455, "LATUDA": 1.4724469207660709, "LEVOFLOXACIN": 1.1195241475949818, "LYRICA": 0.9405822054246468, "MMRVAXPRO": 0.43963504535276, "OLANZAPINE": 0.800569997603295, "OPSUMIT": 0.5089811503971384, "OPTIMARK": 14.429060955606436, "OXYBUTYNIN": 4.936565431236237, "PEGASYS": 0.3981300993511734, "PEGINTRON": 0.9380710325136694, "PLAVIX": 0.3111540786025593, "PREGABALIN": 3.42682494231502, "SHINGRIX": 1.5204204658457814, "SPIKEVAX": 1.137244828739609, "SPINRAZA": 3.501321337847505, "STELARA": 0.3584459239404609, "SUBOXONE": 0.5916183491802137, "SUTENT": 0.3085593215135856, "TOVIAZ": 4.817108927544359, "TOZINAMERAN": 2.2376296785631147, "VAXZEVRIA": 1.022772450922797, "XELJANZ": 0.5079908171181674, "XOLAIR": 0.4602207920706113, "XYREM": 6.2617087744399615, "ZOSTAVAX": 0.4036237299932298, "ZYPREXA": 0.9082242799076744, "null": 0.9702798784328488}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7847.json
index c9b8403d705..20c0c64ea1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7847.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7847.json
@@ -1 +1 @@
-{"ADENURIC": 4.778796087495595, "AMINOSALICYLIC": 1.8456575669306672, "AVANDIA": 1.4876807925297308, "BEDAQUILINE": 3.55551732828071, "CHAMPIX": 1.6390788805226872, "EFIENT": 11.684375460323032, "ELIQUIS": 1.3504453193527262, "ENTRESTO": 5.656351127387332, "EPIVIR": 3.73143393117829, "ESOMEPRAZOLE": 2.201333354742532, "EVENITY": 4.108090162567711, "HARVONI": 4.510365483104159, "ICLUSIG": 3.120851558584854, "INCIVO": 1.3013280456293497, "JAKAVI": 2.0800205949835164, "KALETRA": 2.165854177618717, "KEPPRA": 2.789158769405959, "KEYTRUDA": 1.288850920956951, "KYPROLIS": 2.90004545709605, "LATUDA": 1.956675788197104, "MIDAZOLAM": 2.672468995177815, "MULTAQ": 3.38538492458209, "NEORECORMON": 33.9341003316681, "NEXAVAR": 1.4249631682145891, "OLANZAPINE": 3.5164558949664677, "OLYSIO": 5.140131934387264, "OPDIVO": 1.1023838048800725, "OPSUMIT": 3.044891098987419, "PLAVIX": 1.1185475117613628, "PRADAXA": 7.912163178128317, "PREVENAR": 4.549799579895668, "REVATIO": 2.141028952056084, "SILDENAFIL": 3.613650152188775, "SOMATROPIN": 18.379653723577015, "SPINRAZA": 4.056151798283298, "SYNAGIS": 4.802617068440646, "TAMIFLU": 6.505371193564982, "TASIGNA": 1.261084921949478, "TRACLEER": 6.911537933427729, "VIAGRA": 5.247155493449808, "VICTOZA": 1.6104052703766911, "VIMPAT": 1.6772975374459314, "ZYPREXA": 7.7719381651965245, "null": 1.0432763064698818}
\ No newline at end of file
+{"null": 2.1524943696351264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7848.json
index 6997efefd35..86b4d60b9ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7848.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7848.json
@@ -1 +1 @@
-{"CHAMPIX": 1.3570958535094015, "COMIRNATY": 3.4762712786651027, "PEGASYS": 2.162228198410713, "PEGINTERFERON": 2.9991412085072646, "PEGINTRON": 5.70686964067958, "ROACTEMRA": 2.092543426129972, "SHINGRIX": 1.966114842170615, "SILDENAFIL": 7.163089731070371, "SPIKEVAX": 1.90873652457626, "STELARA": 1.046186797188135, "TOZINAMERAN": 1.2249282888382589, "VAXZEVRIA": 1.7429608966257917, "VIAGRA": 10.130752094237904, "ZOSTAVAX": 1.2498900239605508}
\ No newline at end of file
+{"ABILIFY": 1.1999176128157958, "AIMOVIG": 3.8506380171785, "APIXABAN": 6.692489969373006, "AUBAGIO": 0.5405807869142769, "BEXTRA": 10.747460803875107, "BRIDION": 2.3655911656987265, "BRINTELLIX": 1.776849818806642, "BRIVIACT": 3.130991179562926, "BUPRENORPHINE": 0.4252110416285644, "CAPECITABINE": 0.5886343376718051, "CELSENTRI": 5.826827876328659, "CHAMPIX": 0.5599504555871222, "CICLOSPORIN": 0.1260482007370268, "CIMZIA": 0.1136774622851345, "COMIRNATY": 1.8776272700961856, "COSENTYX": 0.1724215387290913, "CYMBALTA": 2.0885743585992183, "DEXAMETHASONE": 1.1985145461319064, "DOXORUBICIN": 1.4134287639072132, "DULOXETINE": 0.9645818964302656, "ELIQUIS": 0.0823611072325258, "ENBREL": 0.2932915581608987, "FAMPYRA": 0.7604432334495492, "FENTANYL": 1.600564671335068, "FILGRASTIM": 2.3890805251928344, "FIRDAPSE": 1.635235205853985, "GARDASIL": 3.192684277248285, "HIZENTRA": 0.5425044818159062, "IBRANCE": 0.116371059903579, "IBUPROFEN": 0.3797589597948353, "INFANRIX": 2.712241082834932, "JANUVIA": 0.3947415556318853, "KAFTRIO": 0.856750583939655, "KEPPRA": 2.308438249654619, "LACOSAMIDE": 2.033885156191307, "LANTUS": 0.1510016797184016, "LATUDA": 1.9223750559093356, "LEVETIRACETAM": 2.412541363672651, "LEVOFLOXACIN": 1.9945555790796028, "LOXAPINE": 12.193786743794403, "LYRICA": 1.97454231858874, "MIDAZOLAM": 1.3743752290515092, "MMRVAXPRO": 0.5686710718083171, "NEXAVAR": 0.1618669108587341, "NIMENRIX": 0.6691190804161776, "OCRELIZUMAB": 1.3675577371569598, "OLANZAPINE": 1.1214316951440508, "OPSUMIT": 0.2157435062785936, "PEGASYS": 0.2333676461754518, "PEGINTRON": 0.1903341825279029, "ROTATEQ": 0.8674896163618734, "SHINGRIX": 0.3539935793023152, "SPIKEVAX": 1.250728823478399, "STELARA": 0.345863041737393, "SUBOXONE": 1.403629273947369, "SUTENT": 0.121170419357379, "SYCREST": 3.480614704247663, "TAMIFLU": 0.5722374670989402, "TOZINAMERAN": 2.213556776085967, "TWINRIX": 2.660815696629773, "VAXZEVRIA": 0.958660167571067, "VIMPAT": 1.0949487921217955, "XELJANZ": 0.1223892139170828, "XOLAIR": 0.3177742443106658, "XTANDI": 0.8239049006024449, "ZOSTAVAX": 0.1937003335772763, "ZYPADHERA": 2.5134405385365186, "ZYPREXA": 1.1933643066092805, "null": 1.1604042455346288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7849.json
index 87412638c96..e9c102a1f21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7849.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7849.json
@@ -1 +1 @@
-{"HEXYON": 234.6567004896544, "INFANRIX": 73.72642031541899, "PREVENAR": 93.29158502596154, "ROTATEQ": 45.34884902881807, "SUBOXONE": 15.345675311234537, "SYNAGIS": 133.33402067364332, "null": 1.4976835049735608}
\ No newline at end of file
+{"null": 1.1238236439244509}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/785.json
index eecdbc5b576..a3f0d83954b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/785.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/785.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 166.45061512156218, "COVID19": 1.6533782297391162, "TOZINAMERAN": 2.832154469550382}
\ No newline at end of file
+{"KEPPRA": 23.467818565260785, "null": 3.882102101056255}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7850.json
index 0092925b257..6cc0aea1106 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7850.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7850.json
@@ -1 +1 @@
-{"AZILECT": 61.26216181591614, "CARBIDOPA": 110.3429559292266, "COMTAN": 117.08395008402184, "LYRICA": 5.416030893573151, "SIFROL": 105.48880376705112, "STALEVO": 37.57989661377093, "null": 2.139047106151979}
\ No newline at end of file
+{"SIMPONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7851.json
index 1c8660b5990..5ce6e092975 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7851.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7851.json
@@ -1 +1 @@
-{"BRIVIACT": 107.99430888683808, "FYCOMPA": 107.67430235135168, "KEPPRA": 42.73296686299671, "LACOSAMIDE": 60.46357006754184, "LEVETIRACETAM": 94.57816240155756, "VIMPAT": 95.01405375128653, "null": 1.008758532198398}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7852.json
index 581d9238d88..851a93e331d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7852.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7852.json
@@ -1 +1 @@
-{"EYLEA": 60.4421654417824, "PEGASYS": 6.140997253798575, "TOZINAMERAN": 1.511301438029952}
\ No newline at end of file
+{"AFINITOR": 1.0600373905760776, "APROVEL": 5.623627501616175, "ARAVA": 0.1509896331254568, "ATRIPLA": 0.1615150828681764, "BENLYSTA": 1.257043114896368, "BENRALIZUMAB": 8.3763300573528, "BONVIVA": 3.539006726393864, "BUDESONIDE": 0.8597601808218743, "BUPIVACAINE": 2.111480637644021, "BYETTA": 1.143941496250248, "CHAMPIX": 2.6063396790172555, "CIMZIA": 0.2419219880141324, "CLOPIDOGREL": 0.3906683134515668, "COMIRNATY": 1.4753971135036594, "COSENTYX": 1.4948209492429072, "CYMBALTA": 0.2358245047067874, "DEXAMETHASONE": 1.3365223113906, "ELIQUIS": 0.3937573882539538, "ENBREL": 0.5115645656453283, "ENTYVIO": 1.7874241876856989, "ESBRIET": 1.2609585429229386, "EVENITY": 1.905224395247252, "EXJADE": 0.7719000888475303, "FASLODEX": 3.36273346332334, "FIRDAPSE": 3.727798313730399, "FORSTEO": 2.6651434596131174, "GARDASIL": 1.465382942251264, "HEPSERA": 6.291496500752625, "HUMALOG": 0.2967792078908165, "IBRANCE": 3.2017079246401745, "INLYTA": 1.3683316263874838, "JANUMET": 0.9112500541819478, "JANUVIA": 0.7509756418572531, "KAFTRIO": 1.8451580551807032, "KEYTRUDA": 0.4052443791631626, "KISQALI": 1.996868982313528, "LEFLUNOMIDE": 4.719948239524133, "MEPOLIZUMAB": 8.122462130670872, "METHOTREXATE": 0.5374320567292046, "MODERNA": 1.4569086750376616, "NEULASTA": 2.519130174600301, "NEXAVAR": 0.922381945128541, "OCRELIZUMAB": 1.9760424153059264, "OMALIZUMAB": 0.8512202844324166, "OPSUMIT": 0.4103266150297215, "OXYBUTYNIN": 13.129472780261862, "PANTOPRAZOLE": 1.436800241405998, "PEGINTRON": 0.48063592070588, "RINVOQ": 0.8295728315483109, "SHINGRIX": 1.616372364805426, "SIMPONI": 0.6846615626881106, "SPIKEVAX": 1.2413289665198517, "STELARA": 0.696588786759726, "SUTENT": 1.1988570075874234, "TOZINAMERAN": 2.2784502695293862, "TRUVADA": 0.1129935393077416, "VAXZEVRIA": 1.3050800168321592, "VOTRIENT": 1.4393363029008317, "XELJANZ": 1.0936248768157215, "XOFIGO": 2.951175256135856, "XOLAIR": 1.093665986899721, "XTANDI": 1.931636994236388, "ZARZIO": 11.490152077859197, "ZOSTAVAX": 1.5470734860708817, "null": 0.5611123845263748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7853.json
index c655f39bd3b..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7853.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7853.json
@@ -1 +1 @@
-{"BRILIQUE": 7.012223447903515, "BUDESONIDE": 1.2484579431589586, "CHAMPIX": 1.8180534851463048, "FORSTEO": 1.7389275654554273, "XOLAIR": 2.384472788429843, "null": 2.7355252856779115}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7854.json
index 5f27b3c783e..788eaf01f99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7854.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7854.json
@@ -1 +1 @@
-{"ABILIFY": 2.457773213672281, "ARIPIPRAZOLE": 4.0640797031411084, "BRINTELLIX": 5.196808085591319, "BRIVIACT": 14.35262861933545, "CHAMPIX": 25.495078637256118, "CIMZIA": 1.362548714207576, "CYMBALTA": 7.516592005680359, "KEPPRA": 11.176884936208932, "LATUDA": 12.417734567667315, "LEVETIRACETAM": 5.902091469188544, "OLANZAPINE": 3.7922439842708897, "PEGASYS": 1.0277834091161115, "SUBOXONE": 2.6262076740942746, "TAMIFLU": 3.0178903355472477, "ZYPREXA": 3.0942742959344445, "null": 2.4893591276071683}
\ No newline at end of file
+{"ABATACEPT": 94.3016459929373, "ADALIMUMAB": 27.880025492883345, "ENBREL": 25.15540203315701}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7855.json
index 9c1ff7535d1..dc20e29e500 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7855.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7855.json
@@ -1 +1 @@
-{"ABILIFY": 4.838090286753683, "ACETAMINOPHEN/OXYCODONE": 8.057830598170321, "AGOMELATINE": 9.64852572009864, "AIMOVIG": 1.7978842659874563, "ALL": 2.0736348445088155, "ARIPIPRAZOLE": 3.1130531623117155, "ATAZANAVIR": 13.932797348303165, "BENLYSTA": 2.2477684798178448, "BENZODIAZEPINE": 1.3752707017673724, "BETAFERON": 1.3166266581264, "BIKTARVY": 2.8649128766169167, "BREXPIPRAZOLE": 15.985482624953669, "BRINTELLIX": 13.18737448286065, "BRIVARACETAM": 5.3183167014938695, "BRIVIACT": 11.144015421193409, "BUPRENORPHINE": 2.9902942532345143, "CABOTEGRAVIR": 2.390588825279849, "CANAGLIFLOZIN": 5.303744612705502, "CANNABIDIOL": 1.5943903620595348, "CAPSAICIN": 6.526078845143178, "CARIPRAZINE": 12.797176828077571, "CHAMPIX": 27.712921871308144, "CIRCADIN": 1.5959578843580997, "COMTAN": 1.8391991855098588, "CYMBALTA": 18.566736610768658, "DESCOVY": 1.936199552547465, "DESLORATADINE": 1.108164516512502, "DOVATO": 4.502416794398693, "DULOXETINE": 4.345242159670056, "DUPIXENT": 1.2358097474831755, "EBIXA": 1.31345632433455, "EMTRICITABINE": 1.0860834988748505, "ENFUVIRTIDE": 7.090756800520585, "ERTAPENEM": 4.3421375079959725, "ESKETAMINE": 84.48162649632071, "EXVIERA": 1.2979814382852028, "FYCOMPA": 8.418510214846759, "INFLIXIMAB": 1.270377218533197, "INTERFERON": 1.28310439141678, "INTRONA": 4.438242023091989, "INVEGA": 2.302649916692346, "ISENTRESS": 1.6244054624915305, "KAFTRIO": 2.8808845881947107, "KEPPRA": 7.095066590535667, "LACOSAMIDE": 1.3348999888374995, "LATUDA": 26.10870667323299, "LEVETIRACETAM": 2.750252117852118, "LURASIDONE": 7.637357998055891, "LYRICA": 2.792754734403592, "MELATONIN": 1.2197333678790043, "MEMANTINE": 1.7341278947677723, "OLANZAPINE": 2.6097991421378803, "ORKAMBI": 1.3885686646802795, "PEGASYS": 4.10570553554784, "PEGINTERFERON": 1.0449720987493962, "PEGINTRON": 3.1354626028712, "PERAMPANEL": 4.93186003540748, "PLEGRIDY": 1.4445123426185988, "PRAMIPEXOLE": 5.748310049704841, "PREGABALIN": 1.5834559384168532, "PROPRANOLOL": 1.6085277634337318, "RASAGILINE": 14.328539877611613, "REBETOL": 1.0983558557655286, "REBIF": 2.160959104690464, "RIBAVIRIN": 1.456748662290281, "RISPERIDONE": 4.842102569902428, "RYBELSUS": 1.6417883265396331, "SAXENDA": 3.968819433549519, "SERTRALINE": 4.669139802160048, "SIFROL": 1.8538625801515816, "SOVALDI": 1.1556860303552587, "SUBOXONE": 5.37430902588306, "SUSTIVA": 5.695086941939819, "SYCREST": 3.0313231557855578, "TAMIFLU": 2.011255180203694, "TESTOSTERONE": 1.810351297884025, "TIVICAY": 6.1280402287620594, "TRIUMEQ": 7.231263881099052, "VALDOXAN": 3.434444399055876, "VARENICLINE": 12.380166911804343, "VIMPAT": 5.340918290497152, "VORTIOXETINE": 7.8814558191555, "WAKIX": 7.910600710596054, "XEPLION": 4.61463585452843, "XYREM": 5.22832178953762, "ZEPATIER": 1.6629914907717651, "ZYPREXA": 3.47952479444643, "null": 2.011204755751704}
\ No newline at end of file
+{"AFINITOR": 0.4648512729490618, "AIMOVIG": 0.4210941217622175, "ARAVA": 0.7880031579022708, "ATRIPLA": 0.2077524925414146, "AUBAGIO": 1.2077044720935146, "BENLYSTA": 1.7141309443425965, "BYDUREON": 0.8567753083560956, "BYETTA": 0.7261630505247927, "CHAMPIX": 0.3404192843219946, "CICLOSPORIN": 0.4444759610480265, "CIMZIA": 0.6943344691685344, "COMIRNATY": 1.3598487055551425, "COSENTYX": 3.535324228080897, "CYMBALTA": 0.633426988569546, "ELIQUIS": 0.549567906682077, "ENBREL": 5.866971795620636, "ENTRESTO": 0.4574627769215103, "EXFORGE": 0.913316159730587, "EXJADE": 0.7744970095095796, "FASLODEX": 1.4704766206066031, "FENTANYL": 0.401021641554507, "FORSTEO": 2.404211225708773, "FULVESTRANT": 3.442372112815428, "GARDASIL": 0.4380961348058929, "HUMALOG": 0.911665491550022, "HUMIRA": 1.6076021886777347, "IBRANCE": 1.0678738146460518, "IRBESARTAN": 9.953365071502423, "JANUVIA": 0.5368261101708621, "JARDIANCE": 0.3863311242171642, "KEYTRUDA": 0.2681836283390737, "LANTUS": 0.4427831792519864, "LEVOFLOXACIN": 1.126507165299618, "LYRICA": 1.0323897686058527, "MEPOLIZUMAB": 0.7640845876445355, "METHOTREXATE": 0.65627783883531, "MODERNA": 1.829523426902087, "NIMENRIX": 1.107301837831561, "OMALIZUMAB": 0.6684777213928169, "OPSUMIT": 0.6974320077884026, "OXYBUTYNIN": 4.386520725029194, "PEGASYS": 0.1881542873233312, "PEGINTRON": 0.6193869492257817, "PLAVIX": 0.3503134733295176, "RINVOQ": 1.798125644971167, "SHINGRIX": 1.038022936086468, "SOLIRIS": 0.5910700110708512, "SPIKEVAX": 1.4003279009624383, "STELARA": 0.4389724911306061, "SUBOXONE": 1.2675220986328164, "SUTENT": 0.9587956833990788, "TOZINAMERAN": 1.9219034541358664, "TRACLEER": 0.756415865865129, "TRUVADA": 0.1245463341687722, "VAXZEVRIA": 0.977729808919338, "VIAGRA": 0.6957380948271045, "XELJANZ": 2.54766720811612, "XOLAIR": 0.986002532433524, "XTANDI": 0.8981255015113456, "ZOSTAVAX": 1.1062789564485278, "null": 0.779814158434837}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7856.json
index 562a416cf23..aea7bc5e3e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7856.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7856.json
@@ -1 +1 @@
-{"ABILIFY": 15.295255075273252, "AERIUS": 3.833707595281592, "AGOMELATINE": 4.243832930264444, "ALL": 3.4435101199441016, "ARIPIPRAZOLE": 11.118826854885564, "AXURA": 9.169613523031614, "AZILECT": 2.629735575778812, "BARACLUDE": 1.1300073633704488, "BENZODIAZEPINE": 5.833795972754047, "BENZODIAZEPINES": 5.9510149231212095, "BETA": 6.692608583967592, "BETADORM": 78.03396815773459, "BETAFERON": 1.3521214231046632, "BIKTARVY": 1.3112699235760643, "BRINTELLIX": 4.42011278737771, "BRIVARACETAM": 1.2124927999540316, "BUPRENORPHINE": 2.729006637667482, "CHAMPIX": 6.454842003398301, "CIRCADIN": 4.480373400572181, "COMTAN": 1.3963394879479158, "CYMBALTA": 7.225240397195066, "DESLORATADINE": 1.289259579829502, "DULOXETINE": 4.8463871528996485, "EMTRICITABINE": 1.3453933574442458, "EPIVIR": 1.0237601466677886, "ESOMEPRAZOLE": 12.107441516949448, "EXFORGE": 1.120060196365934, "FYCOMPA": 12.30075627524149, "GENVOYA": 1.3206534800766108, "GLIBENCLAMIDE": 3.2095868498185336, "GLUCAGON": 1.9627861739071344, "HUMALOG": 1.1445810745166518, "HYDROCHLOROTHIAZIDE": 2.6614860996521035, "IBUPROFEN": 12.69977664635386, "INSULIN": 1.492507461146635, "INTRONA": 3.197394006889928, "INVEGA": 7.447787336658952, "IVABRADINE": 5.841694981373992, "KAFTRIO": 1.4755475262652948, "KALETRA": 1.1836782256148404, "KEPPRA": 5.602345788795961, "LACOSAMIDE": 1.393660069891166, "LANTUS": 1.064812342854226, "LATUDA": 6.126282653605212, "LEVETIRACETAM": 1.7664538167391903, "LEVODOPA": 1.5574614055499674, "LOXAPINE": 5.288660770896732, "LYRICA": 3.544014270839005, "MELATONIN": 3.6527397080740527, "MICARDIS": 1.0789050036792098, "MIDAZOLAM": 1.085760310554504, "MIXTARD": 1.7747556636270383, "NALOXONE": 9.202474161478769, "NORVIR": 1.0729744920915614, "NOT": 2.4339439790766195, "NOVORAPID": 2.7650058371984563, "OLANZAPINE": 5.049573598934948, "OTHER": 7.229269849543266, "OXYBUTYNIN": 1.2537380444358217, "PEGASYS": 1.8279025853688624, "PEGINTRON": 1.9405870149046491, "PERAMPANEL": 8.905146422301383, "PREGABALIN": 2.683164843290036, "PROPRANOLOL": 1.106865870085842, "REBETOL": 2.1258447297036347, "RISPERIDONE": 2.150143598807894, "RIVAROXABAN": 2.211895002782046, "SIFROL": 6.288174730926103, "STALEVO": 1.7450381953314749, "STOCRIN": 5.525759789595508, "SUBOXONE": 1.3319623750429344, "SYCREST": 5.416595422515599, "TAMIFLU": 1.1042950130181746, "TIVICAY": 2.0921659789941742, "TRESIBA": 3.847560914975192, "TRICYCLIC": 27.074442430164652, "TRIUMEQ": 2.3458293195650377, "UNKNOWN": 3.3268348105228718, "UNSPECIFIED": 3.84377613574144, "VALDOXAN": 21.262379493595496, "VARENICLINE": 3.321872733562656, "VIMPAT": 3.241727123380294, "XEPLION": 7.852130505708266, "XYREM": 5.339331875882588, "ZYPREXA": 8.289200141312431, "null": 3.575924605264492}
\ No newline at end of file
+{"ABATACEPT": 1.3341586149096616, "ACETYLSALICYLIC": 92.03390998502832, "ADALIMUMAB": 3.238516872931208, "AIMOVIG": 0.99574772519917, "ANAKINRA": 47.33083741422998, "ARAVA": 5.051722287851697, "ATRIPLA": 0.6748736613770051, "AUBAGIO": 4.449610766319105, "AVANDIA": 0.9040977891744058, "CELECOXIB": 2.940669710012466, "CIMZIA": 0.6676199751140541, "COMIRNATY": 0.6364777868222801, "COSENTYX": 0.4486318800317413, "CYMBALTA": 0.2682877536454949, "ENBREL": 6.068370078237419, "FAMPYRA": 23.03025692260576, "FASLODEX": 1.2407277144478197, "HUMALOG": 2.0096572172203158, "HUMIRA": 3.410335004712974, "IBRANCE": 1.1322611350224614, "LANTUS": 1.03193731100021, "LEMTRADA": 1.843219399715879, "LEVOFLOXACIN": 0.7436295423577045, "LYRICA": 1.9469021577213623, "METHOTREXATE": 1.2927151687245106, "NEXAVAR": 0.5400430938411381, "OPTIMARK": 2.254141959187124, "PEGASYS": 0.5634535862616972, "PEGINTRON": 3.585454259027174, "PLAVIX": 0.3885654128546177, "PLEGRIDY": 9.785486587622117, "REVATIO": 3.578501469580054, "RINVOQ": 4.637191805398272, "SIMPONI": 0.5691338935344756, "SPIKEVAX": 0.5147632767346781, "SUBOXONE": 1.6846510455212993, "SUTENT": 0.6554593596077277, "TOVIAZ": 8.345203948297033, "TOZINAMERAN": 0.978698878355552, "TRULICITY": 1.2352401474558434, "TRUVADA": 0.8223568795943564, "VAXZEVRIA": 0.147724403219118, "VIAGRA": 9.388951844297644, "XELJANZ": 3.4343681415577905, "ZOSTAVAX": 1.625546300304278, "null": 0.6817563930077705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7857.json
index 9b445337285..1cb32598864 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7857.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7857.json
@@ -1 +1 @@
-{"null": 1.81501773900504}
\ No newline at end of file
+{"LEVOFLOXACIN": 24.0227377771002, "null": 7.59807558831324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7858.json
index 645dbcbd8b9..acf37490ea9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7858.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7858.json
@@ -1 +1 @@
-{"SOMATROPIN": 1290.8221809123604, "null": 1.57529124026637}
\ No newline at end of file
+{"ABACAVIR": 0.192739780407354, "ABATACEPT": 8.040490428855728, "ACLASTA": 5.539037358927272, "ADALIMUMAB": 3.1773361366869346, "AFINITOR": 2.0613158892128367, "AIMOVIG": 0.2043802671293111, "AMINOSALICYLIC": 1.3707713241348347, "ANAKINRA": 15.97826001531265, "APIXABAN": 0.2772576748038141, "APREMILAST": 9.06383803522002, "ARAVA": 4.061322460784969, "ATRIPLA": 0.0493846853046894, "AUBAGIO": 0.6576212715688906, "AVASTIN": 0.4044455380477965, "AZACITIDINE": 1.2483418660791756, "AZATHIOPRINE": 1.7137036279466171, "BONVIVA": 4.984593009101706, "BUPIVACAINE": 0.9975538684009192, "CHAMPIX": 0.2249223678430251, "CICLOSPORIN": 0.7011323378689195, "CIMZIA": 1.2272586028484314, "CLOPIDOGREL": 0.3652786115874049, "COMIRNATY": 2.089795467675573, "COSENTYX": 3.970822634614186, "CYMBALTA": 2.1399937820730126, "CYTARABINE": 0.3505404115949428, "DASATINIB": 2.4133468589826985, "DOCETAXEL": 0.8748170446996469, "DONJOY": 599.3138099904689, "DULOXETINE": 1.9231515793484115, "ELIQUIS": 0.4163311412014463, "ENBREL": 7.087215249747964, "ESMYA": 3.7393132635546578, "EVEROLIMUS": 1.984656987261422, "EVISTA": 1.6007031129428548, "FAMPYRA": 1.1489833142941432, "FASLODEX": 3.3305322488135696, "FENTANYL": 0.3000386097326042, "FILGRASTIM": 1.6369336428017278, "FIRDAPSE": 1.993612497053276, "FORSTEO": 1.4216777120130546, "FULVESTRANT": 1.0027960522200607, "GARDASIL": 1.082796011469023, "HUMALOG": 0.1131205252606274, "HUMIRA": 2.1845624963066523, "IBRANCE": 0.3544102120382834, "IBUPROFEN": 0.3453724925245106, "IFLOW": 661.1240093632636, "INCIVO": 0.6348908055318262, "JAKAVI": 0.425873975812904, "JANUVIA": 0.3656251773392033, "JARDIANCE": 0.1479938832873802, "KEYTRUDA": 0.3696827768310624, "LANTUS": 0.2147064681854963, "LEFLUNOMIDE": 2.3515488676030785, "LEVOFLOXACIN": 0.3983136898159689, "LYRICA": 0.5429574208957958, "METHOTREXATE": 1.0976274677657658, "MODERNA": 1.9002320799228916, "NEULASTA": 2.425379675115351, "NEXAVAR": 0.3952863872782373, "NUCALA": 0.5003862353436054, "OMALIZUMAB": 1.417439955760983, "OPSUMIT": 0.4001043701899125, "PAIN": 135.39174423901332, "PANTOPRAZOLE": 1.2796221366649536, "PEGASYS": 0.733695858842911, "PEGINTRON": 0.1731000811913775, "PEMBROLIZUMAB": 0.8552806829377044, "RITUXIMAB": 1.6503576113845024, "SHINGRIX": 0.9868334076108874, "SPIKEVAX": 0.7209017670040061, "SPRYCEL": 1.5153809353228065, "STELARA": 0.413558705704001, "SUTENT": 0.5557661175359593, "TASIGNA": 1.541103480565274, "TOZINAMERAN": 0.7048177570028701, "TREMFYA": 0.7566885291232649, "TRUVADA": 0.1101774391923022, "VAXZEVRIA": 1.0561717463325526, "VORICONAZOLE": 2.3127547665720374, "VOTRIENT": 0.4170343609221518, "XELJANZ": 0.6536585230672539, "XOLAIR": 1.0543524956795478, "XTANDI": 0.7117702864633283, "ZOSTAVAX": 1.0493019293602908, "ZYPREXA": 0.1675926296213684, "null": 0.3776482995359985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7859.json
index 5f7512101ba..a94930bc822 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7859.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7859.json
@@ -1 +1 @@
-{"COSENTYX": 3.093040029734667, "COTELLIC": 17.956077288190652, "ESBRIET": 48.76534194596079, "OLYSIO": 74.22520496059998, "PEGASYS": 1.0240263725001977, "RUBRACA": 13.300510090289832, "SUTENT": 1.2519746832079646, "VFEND": 15.33528110313298, "XOLAIR": 1.7922048853321555, "ZELBORAF": 163.6866523612104, "null": 1.5716231798925882}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/786.json
index b307b72a767..81ae52ed1b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/786.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/786.json
@@ -1 +1 @@
-{"LATUDA": 58.86945696779946}
\ No newline at end of file
+{"KEPPRA": 10.517459379000629, "LACOSAMIDE": 59.6952048166675, "LEVETIRACETAM": 30.799991497847827, "null": 4.264315149186621}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7860.json
index 3c80da32314..fe9a3eea564 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7860.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7860.json
@@ -1 +1 @@
-{"null": 2.516331049844454}
\ No newline at end of file
+{"ABILIFY": 6.846735747650685, "ARIPIPRAZOLE": 20.354329824888232, "COMIRNATY": 0.2612181962693071, "KEPPRA": 5.780998325531608, "OLANZAPINE": 20.67792722801024, "SUTENT": 1.8468179205008808, "TOZINAMERAN": 1.3364423837325885, "XELJANZ": 2.4836872603540336, "ZYPREXA": 7.974915111242755, "null": 1.5935088615785928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7861.json
index 2bcc0d03a36..996f3f582f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7861.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7861.json
@@ -1 +1 @@
-{"CIALIS": 572.684034684605, "VIAGRA": 136.80159954403308}
\ No newline at end of file
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"RASILEZ": 0.1760184288390048, "REBETOL": 0.3031990386745357, "REKAMBYS": 0.9849929872542472, "RELVAR": 0.3777042966261681, "REMICADE": 0.1007053977049559, "REPATHA": 2.185215636451157, "REVATIO": 0.1236086024720908, "REVLIMID": 0.0506129013833495, "REYATAZ": 0.3399937912361237, "RIBAVIRIN": 0.0425657802308009, "RINVOQ": 0.2482248707979074, "RITUXIMAB": 0.0446002103672673, "RIVAROXABAN": 0.1585471855236359, "RIXATHON": 0.1370459718622449, "ROACTEMRA": 0.1474117412416128, "RUBRACA": 0.0930179928218421, "RYBELSUS": 0.1310154978208016, "SAXENDA": 0.0429876201772916, "SCEMBLIX": 1.41113716177195, "SEMAGLUTIDE": 2.0151036703337253, "SHINGRIX": 1.133570453690698, "SIFROL": 0.0791041198552913, "SILDENAFIL": 0.1218705403027746, "SIMEPREVIR": 0.2407749865233861, "SIMPONI": 0.0716715730959288, "SKYRIZI": 0.1993767139425845, "SOLIRIS": 0.1112983390718749, "SOVALDI": 0.1665326711415126, "SPIKEVAX": 3.4788886831647923, "SPINRAZA": 0.1095941849500891, "SPIRONOLACTONE": 0.0454363954290879, "SPRYCEL": 0.2437021110451986, "STALEVO": 0.0756625363288293, "STELARA": 0.6723939279078355, "STIVARGA": 0.1143169162193449, "STRIBILD": 0.0479816228685507, "SUBOXONE": 0.0591980884493707, "SUTENT": 0.0976754722677852, "SYMTUZA": 0.3350166306408295, "TAFINLAR": 0.2340897086233472, "TAGRISSO": 0.0927606632912166, "TAMIFLU": 0.0980538734722954, "TASIGNA": 0.3398714538332389, "TAXOTERE": 0.1560323705173506, "TELMISARTAN": 0.267201030392636, "TENOFOVIR": 0.2495686384457369, "TERIFLUNOMIDE": 0.3823334885603381, "TERIPARATIDE": 0.3174349764542637, "TERROSA": 0.6802989175347269, "THALIDOMIDE": 0.0587078768307721, "TICAGRELOR": 0.0828293817562257, "TIVICAY": 0.4170393524649387, "TORISEL": 0.0528147679945797, "TOUJEO": 0.161996518746896, "TOVIAZ": 0.0672326130691058, "TOZINAMERAN": 1.1404137518459083, "TRACLEER": 0.0700214415367859, "TREDAPTIVE": 5.535939184449084, "TRELEGY": 0.0945339289605208, "TREMFYA": 0.308760948637783, "TRESIBA": 0.1534732376095756, "TRIUMEQ": 0.4689821206103846, "TRULICITY": 0.065151863514083, "TRUVADA": 0.0204448509971876, "TWINRIX": 0.77828619447906, "UPADACITINIB": 0.1937373934613263, "UPTRAVI": 0.5299262756458759, "VAXZEVRIA": 4.538089467307391, "VEDOLIZUMAB": 0.215457333233402, "VELMETIA": 0.3357100684887106, "VENCLYXTO": 0.1280665299960802, "VFEND": 0.093773493096082, "VIAGRA": 0.0616092821190869, "VICTOZA": 0.0689717893980126, "VIMPAT": 0.0333850069629979, "VIRAMUNE": 0.2923528327705845, "VIREAD": 0.1371117348887026, "VORICONAZOLE": 0.0652734544180994, "VOTRIENT": 0.1049560186125493, "XALKORI": 0.0446534052880382, "XARELTO": 0.0516139193079586, "XELJANZ": 0.1262190513935019, "XOFIGO": 0.0473182607345423, "XOLAIR": 0.4126709307149835, "XTANDI": 0.2554157736836261, "XYREM": 0.0588040583234736, "YERVOY": 0.0687261752368369, "YESCARTA": 0.0846212156752656, "YONDELIS": 0.3288080434717316, "ZARZIO": 0.7102815791331016, "ZEJULA": 0.3699821002152003, "ZELBORAF": 0.5067598844574489, "ZEPATIER": 0.2893016345701575, "ZIAGEN": 1.5078070576161609, "ZOSTAVAX": 0.2430784700876871, "ZYCLARA": 0.5842836723154482, "ZYPADHERA": 0.0591156082419564, "ZYPREXA": 0.0745210793009101, "null": 0.2064977889872159}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7862.json
index 3a61c6487e9..9c0e20b6c61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7862.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7862.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7265579051137334, "VAXZEVRIA": 4.7301865873292455}
\ No newline at end of file
+{"COMIRNATY": 3.903662601455394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7863.json
index f6bf462a85b..beda3e4ec30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7863.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7863.json
@@ -1 +1 @@
-{"ACTRAPID": 9.912164278037086, "APIXABAN": 1.5155409757903595, "ATOSIBAN": 41.86480049884824, "CELECOXIB": 11.24812065123724, "COMIRNATY": 2.68814148709798, "COVID19": 2.2674037620261056, "ELIQUIS": 1.2175882464609369, "EVISTA": 12.333145398673466, "PROTELOS": 19.09748379497525, "RINVOQ": 2.486406732099631, "VAXZEVRIA": 4.312305411734791}
\ No newline at end of file
+{"AXITINIB": 12.116320269294713, "CELLCEPT": 2.75827058153774, "CICLOSPORIN": 0.6651515590223265, "COMIRNATY": 0.5842092612083732, "DARBEPOETIN": 101.68476605696192, "ELIQUIS": 1.048141998298055, "FIRDAPSE": 6.813466680856688, "GARDASIL": 1.396141217148646, "HUMALOG": 0.8449368243779116, "HUMAN": 3.769224988748321, "HUMIRA": 2.330000292524389, "INLYTA": 2.257196993466269, "IPILIMUMAB": 22.77116436963525, "KEPPRA": 0.7170305803445759, "KEYTRUDA": 29.30410881728257, "LANTUS": 0.8299440712056857, "LEVOFLOXACIN": 1.1646615749450675, "MELATONIN": 11.70979131417658, "OPDIVO": 22.258222480237016, "PEGASYS": 1.2496690715676513, "PEGINTERFERON": 2.538010425065013, "PEGINTRON": 1.59773931633655, "PEMBROLIZUMAB": 26.21331138377178, "PRIVIGEN": 2.5112297046233496, "RITUXIMAB": 2.3504252437874524, "SHINGRIX": 0.915846015048843, "SOLIRIS": 43.32096471376138, "SPIKEVAX": 0.7685990427877483, "STELARA": 1.1948104883212936, "TOZINAMERAN": 0.9265341431550832, "VAXZEVRIA": 0.22569884052345, "XOLAIR": 1.1201064247440096, "null": 0.5327203604542097}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7864.json
index a7178ad1cb0..e64f5800970 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7864.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7864.json
@@ -1 +1 @@
-{"IBUPROFEN": 9.612616255094716, "RINVOQ": 11.26687674351851, "null": 1.238152458737092}
\ No newline at end of file
+{"COMIRNATY": 0.1844066426749835, "KEYTRUDA": 9.84456060748407, "PEMBROLIZUMAB": 30.415613830161785, "SOLIRIS": 156.909936016623, "null": 0.5438439211838362}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7865.json
index a63f7185b79..9f09300e63e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7865.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7865.json
@@ -1 +1 @@
-{"ABACAVIR": 23.86035221745633}
\ No newline at end of file
+{"COMIRNATY": 0.2890086847475149, "FIRDAPSE": 594.6413670970958, "IPILIMUMAB": 30.15867478453428, "KEYTRUDA": 15.889813851521874, "OPDIVO": 9.244769872030815, "PEMBROLIZUMAB": 33.766362411198386, "null": 0.7364497151354696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7866.json
index e9bfa757179..5542c566413 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7866.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7866.json
@@ -1 +1 @@
-{"null": 1.921723426875465}
\ No newline at end of file
+{"ADALIMUMAB": 0.9871121341494058, "AMIKACIN": 51.05499789923144, "APIXABAN": 16.751920595163583, "CANAGLIFLOZIN": 179.8936923686781, "CICLOSPORIN": 7.841414514197838, "INVOKANA": 42.24188768373045, "JAKAVI": 9.090337228224843, "LAMIVUDINE": 38.404652003389984, "NUCALA": 5.733980198805928, "XELJANZ": 2.372496330009241, "null": 0.6347148249929874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7867.json
index b6f0fdb73a8..6d4f2e808f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7867.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7867.json
@@ -1 +1 @@
-{"IBUPROFEN": 72.58110008207089, "OMALIZUMAB": 76.96150695666543}
\ No newline at end of file
+{"AMIKACIN": 644.3524522687882, "PEGINTERFERON": 39.40274218024246, "null": 0.9887260893227774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7868.json
index 900c7f43055..0b895b90707 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7868.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7868.json
@@ -1 +1 @@
-{"ASPARAGINASE": 110.17746461657556, "COVID19": 1.9726862557318463, "ONCASPAR": 175.0772413754705, "VAXZEVRIA": 3.813193723787341}
\ No newline at end of file
+{"ABACAVIR": 4.033079831110975, "AMIKACIN": 208.6702244361007, "ATAZANAVIR": 18.570707364427506, "ATRIPLA": 0.4643665313260641, "BENRALIZUMAB": 30.431495001495907, "BIKTARVY": 15.940841457075749, "CICLOSPORIN": 4.212189575294976, "DESCOVY": 39.47881318032175, "EFAVIRENZ": 23.09017350876748, "EMGALITY": 846.56413802355, "EPIVIR": 22.917102689188237, "JAKAVI": 5.451852272314436, "KALETRA": 7.527825759530812, "LAMIVUDINE": 19.15581025306196, "MEPOLIZUMAB": 17.892647380959893, "MYCOPHENOLATE": 13.936788747017497, "NORVIR": 13.744392662934828, "NUCALA": 5.357423256200751, "PEGASYS": 1.390121921238805, "TRELEGY": 9.262850283423733, "TRUVADA": 0.8762054705760799, "XELJANZ": 1.423736554233997, "null": 1.065031859865127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7869.json
index c7ff581381b..d115e5a5d22 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7869.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7869.json
@@ -1 +1 @@
-{"KEYTRUDA": 5.811532128127838}
\ No newline at end of file
+{"ASPARAGINASE": 560.566896846649, "CICLOSPORIN": 26.63183723095713, "MYCOPHENOLATE": 40.13034780871492, "null": 0.461609119103221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/787.json
index 0a2939af3db..c08bdd5e4a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/787.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/787.json
@@ -1 +1 @@
-{"ATRIPLA": 24.29589967410996, "TRUVADA": 9.633760360102928}
\ No newline at end of file
+{"KEPPRA": 15.613129793324951, "LACOSAMIDE": 29.92555352076628, "LEVETIRACETAM": 33.849691263280874, "null": 4.16572444615976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7870.json
index e2998e36555..3bb40932587 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7870.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7870.json
@@ -1 +1 @@
-{"null": 1.609848241428752}
\ No newline at end of file
+{"null": 0.4340993310328067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7871.json
index d21b1fa55ce..ee717d9eeeb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7871.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7871.json
@@ -1 +1 @@
-{"COMIRNATY": 7.565839499100232}
\ No newline at end of file
+{"MYCOPHENOLATE": 295.84022379430326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7872.json
index c9fc1f4d3d5..ad5999edf9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7872.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7872.json
@@ -1 +1 @@
-{"null": 1.47140314749623}
\ No newline at end of file
+{"ALEMTUZUMAB": 119.51710973591938, "CICLOSPORIN": 16.86369085433494}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7873.json
index 31c8c221060..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7873.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7873.json
@@ -1 +1 @@
-{"AVANDIA": 1.3512351343749358, "BRILIQUE": 4.25169353822942, "COMIRNATY": 1.0441233359340123, "CYMBALTA": 1.7450469206214283, "EVEROLIMUS": 21.498535698713088, "FENTANYL": 1.5869566356951483, "FORSTEO": 1.9968472246084568, "IRBESARTAN": 20.880086495906045, "TASIGNA": 5.321136103174236, "ZOSTAVAX": 1.2680561189799773, "ZYPREXA": 2.0136786817885395, "null": 1.5528591655400223}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7874.json
index 50c48c3e965..60dbfd4175f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7874.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7874.json
@@ -1 +1 @@
-{"ACTRAPID": 11.643428819285306, "ARANESP": 3.687987253926973, "AVANDAMET": 9.139617413033282, "AVANDIA": 7.62513411611777, "AVASTIN": 1.2281074708000377, "BRIDION": 12.381290588296403, "CHAMPIX": 1.1074776883028483, "DASATINIB": 31.228357974255932, "ENTYVIO": 1.1975420017817555, "FENTANYL": 2.3549809558614494, "FIRDAPSE": 3.159163250369585, "HUMIRA": 1.764447669665751, "ICLUSIG": 2.224836690995568, "LEVETIRACETAM": 2.713556338607779, "LOPINAVIR": 7.370417183420508, "METHOTREXATE": 1.1035573687174325, "OPSUMIT": 1.067076685492458, "SYNAGIS": 1.983556143974398, "TAMIFLU": 2.7166109327417987, "TRACLEER": 2.076142069136613, "ZYPREXA": 1.852111410440624, "null": 1.9620596635881435}
\ No newline at end of file
+{"LEVOFLOXACIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7875.json
index 7f706c4adba..7ab1dc13bd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7875.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7875.json
@@ -1 +1 @@
-{"null": 1.2695044214265356}
\ No newline at end of file
+{"ABACAVIR": 28.265747711225867, "ACLIDINIUM": 272.05132804874165, "AMINOSALICYLIC": 46.7131363565164, "null": 0.6316770099604113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7876.json
index 0e5fa1cc763..7c2e485b781 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7876.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7876.json
@@ -1 +1 @@
-{"ALBIGLUTIDE": 51.45540116473992, "ANORO": 1.1048816299278568, "APIDRA": 1.1792545182207612, "ARANESP": 1.3826096930452951, "AUBAGIO": 3.3721161132694637, "AVANDIA": 1.0766889902833874, "BARACLUDE": 4.843632526410175, "BENLYSTA": 6.626053796938585, "BRIDION": 1.9897637338501717, "BYETTA": 1.1546754681066116, "CICLOSPORIN": 1.7735174309569213, "CIMZIA": 10.577358921951962, "DAKLINZA": 4.2862405217937285, "ELIQUIS": 6.009813090301468, "ENBREL": 1.7314289550810205, "ENTYVIO": 4.815920517886652, "ERLEADA": 2.164993423318131, "EVENITY": 3.5739627670567877, "EVISTA": 3.441008400318584, "EXJADE": 1.841889218250608, "GALAFOLD": 4.916651430912984, "HIZENTRA": 4.645676131964215, "HUMIRA": 2.337949304889748, "INCRUSE": 4.124536575893146, "JANUMET": 4.001932360641263, "JANUVIA": 3.776308005941461, "JARDIANCE": 4.061396031008372, "KAFTRIO": 8.297899944759154, "KALYDECO": 10.038641397065984, "KEPPRA": 1.7513578035003583, "KEYTRUDA": 1.4653643545515622, "LANTUS": 4.072685878518728, "LEVEMIR": 3.09334220537124, "LONSURF": 2.298846964427156, "LYRICA": 1.4136176524861157, "MIMPARA": 2.374930569350868, "MISOPROSTOL": 40.02432412518667, "NAGLAZYME": 1.730646741791828, "NEULASTA": 3.72286271617434, "NOXAFIL": 2.16621510444783, "NPLATE": 3.460631573381158, "NUCALA": 2.311737178570053, "OCALIVA": 3.3667616356496044, "OFEV": 1.5231439622246212, "OPSUMIT": 3.232402278812138, "ORKAMBI": 4.970935843249374, "RASILEZ": 1.673734728579796, "RINVOQ": 3.3347755421198317, "ROTATEQ": 9.262282280071972, "RUBRACA": 4.27672475825635, "RUCONEST": 4.581646733683935, "RYBELSUS": 2.508260985033779, "SAXENDA": 4.884745912418875, "SIMPONI": 16.494767354827935, "SKYRIZI": 3.857534673620018, "SPRYCEL": 1.4531771015732, "STELARA": 8.179433416478334, "SYNAGIS": 3.8455500331883306, "TEMODAL": 2.435043475799687, "TOUJEO": 3.3646165505663075, "TRACLEER": 2.725809193865039, "TRELEGY": 5.103443256065959, "TREMFYA": 3.432819823791506, "VELTASSA": 15.56228087811788, "VIAGRA": 1.2527479387852958, "VICTOZA": 2.311258768995714, "VIMPAT": 1.2599252729844057, "VOTRIENT": 3.3649221351965504, "XOLAIR": 1.569723565734621, "XTANDI": 1.6456173207893383, "ZOSTAVAX": 1.2055633814301536, "null": 1.394398103629217}
\ No newline at end of file
+{"ARAVA": 4.447759187357514, "CIMZIA": 13.200621705389882, "COSENTYX": 9.644134820402888, "LEFLUNOMIDE": 74.4786979780844, "SIMPONI": 17.59574906046521, "STELARA": 44.64835041912542, "TREMFYA": 43.97696300973906, "XELJANZ": 4.207638492201945, "null": 0.3139621862542242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7877.json
index 04659251c4b..bd46b66332e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7877.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7877.json
@@ -1 +1 @@
-{"ARAVA": 4.603269345261382, "ENBREL": 31.32323377043351}
\ No newline at end of file
+{"null": 18.299729618446563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7878.json
index 27a11f6c365..f4f22529f98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7878.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7878.json
@@ -1 +1 @@
-{"ABACAVIR": 65.91390191458981}
\ No newline at end of file
+{"BIKTARVY": 1155.9796967217178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7879.json
index 92fa072c9e5..bb553456e69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7879.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7879.json
@@ -1 +1 @@
-{"COMIRNATY": 5.208293030269041, "JCOVDEN": 10.87784496951629, "RINVOQ": 2.5153569406371306, "SOLIRIS": 8.466035033613304, "TOZINAMERAN": 23.529649797459346}
\ No newline at end of file
+{"GARDASIL": 16.890791795422807, "TIVICAY": 155.73506054310172, "null": 0.6691261598163164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/788.json
index 50f48c52458..123fb1723f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/788.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/788.json
@@ -1 +1 @@
-{"ANAKINRA": 173.9816138466296, "CIMZIA": 68.66584521638245, "SIMPONI": 19.80655651709543}
\ No newline at end of file
+{"KEPPRA": 10.620374147846348, "LEVETIRACETAM": 21.300144797851804, "null": 6.53322283160817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7880.json
index 19f56b2ab51..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7880.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7880.json
@@ -1 +1 @@
-{"BARACLUDE": 89.52784781182268, "BIKTARVY": 5.342464289449949, "COMPLEMENT": 408.5722481012281, "HUMAN": 7.1070799062503545, "JANUMET": 5.342209508776272, "KEPPRA": 1.229388685442111, "KEYTRUDA": 1.1330258944154383, "LANTUS": 2.553070957193883, "NEXAVAR": 1.4320893574683116, "NOVORAPID": 3.388987555056583, "PEGASYS": 1.420533321871163, "PLAVIX": 5.929053760194957, "SAXENDA": 10.071801270447484, "VEMLIDY": 111.26280859592256, "VIAGRA": 39.69444840473262, "null": 2.195594692323787}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7881.json
index cede2dd02ee..302173bf4f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7881.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7881.json
@@ -1 +1 @@
-{"null": 5.293428798754087}
\ No newline at end of file
+{"COMIRNATY": 0.5646557524171147, "null": 0.466733711871285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7882.json
index f0bda58ead4..ad41ebb211b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7882.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7882.json
@@ -1 +1 @@
-{"EYLEA": 19.89185554968532, "LANTUS": 3.0273377899949354, "NOVORAPID": 4.982845235291706, "null": 9.311970023165166}
\ No newline at end of file
+{"ABILIFY": 4.904933880468693, "ANORO": 1029.335445414839, "APIXABAN": 138.32350758199678, "AZATHIOPRINE": 40.499984391675866, "COSENTYX": 6.425298880534863, "null": 0.1222503687188486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7883.json
index c5c8d141693..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7883.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7883.json
@@ -1 +1 @@
-{"null": 1.4968112868212209}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7884.json
index 98608923448..e8a4a759354 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7884.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7884.json
@@ -1 +1 @@
-{"APIXABAN": 8.717546896345297, "ARIPIPRAZOLE": 10.09989538590415, "BENZODIAZEPINE": 29.675945719772667, "BUDESONIDE": 2.924468233689423, "BUPRENORPHINE": 3.902483120308784, "CARIPRAZINE": 147.71755676053294, "CELECOXIB": 5.70348602968559, "CLOPIDOGREL": 1.8975345043862148, "DULOXETINE": 66.92622136856298, "FENTANYL": 3.929661550782338, "IBUPROFEN": 47.059842522309374, "INSULIN": 4.049623959672664, "LEFLUNOMIDE": 5.308265543540806, "LEVETIRACETAM": 8.528941382301895, "LINACLOTIDE": 138.874140685055, "MELATONIN": 13.56006834994027, "OLANZAPINE": 9.95785460917635, "OXYBUTYNIN": 15.88358502910902, "PANTOPRAZOLE": 13.106112024400746, "PIOGLITAZONE": 32.93100537419011, "PREGABALIN": 9.292541613543138, "RIVAROXABAN": 82.23291132768826, "SUBOXONE": 1.144424346370999, "null": 3.307375996439719}
\ No newline at end of file
+{"null": 0.5245983930141328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7885.json
index d909be13fcb..d1660352e6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7885.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7885.json
@@ -1 +1 @@
-{"null": 3.39784936207953}
\ No newline at end of file
+{"ABILIFY": 2.3586005229799603, "ARIPIPRAZOLE": 1.5473317607346522, "BRINTELLIX": 2.8025792774481, "BUPRENORPHINE": 2.4025492346698525, "CLOPIDOGREL": 0.5310056851501012, "COMIRNATY": 0.1414912323618673, "CYMBALTA": 6.21292241917744, "DEXAMETHASONE": 0.974256235419705, "DULOXETINE": 6.189029275228009, "ENTACAPONE": 10.946730025066095, "FENTANYL": 6.622938706155572, "GARDASIL": 1.8453807463629053, "IBUPROFEN": 2.5652130632079517, "KALETRA": 1.7018874423628525, "KEPPRA": 1.2834484080006912, "LANTUS": 0.2357286298006064, "LEVETIRACETAM": 0.7126412731713019, "LYRICA": 2.4131123186520544, "MELATONIN": 4.537630877683262, "MIDAZOLAM": 5.78200435924204, "NALOXONE": 14.660874080202383, "OLANZAPINE": 2.958038019111347, "PLAVIX": 0.2673623861760096, "PREGABALIN": 9.167445275691472, "QARZIBA": 35.60914388603176, "SPIKEVAX": 0.1410419132774317, "SUBOXONE": 0.6377105974156398, "TOZINAMERAN": 0.2980030844042711, "VALDOXAN": 20.69534154483875, "VAXZEVRIA": 0.0918595380689634, "VIAGRA": 0.6727672200109365, "ZYPREXA": 1.6630736245613005, "null": 5.074808921913614}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7886.json
index c888bf4f501..8cbc6a0124f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7886.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7886.json
@@ -1 +1 @@
-{"BLOOD": 2056.207203755685, "HIZENTRA": 90.52469828045076, "HUMALOG": 8.472359952967983, "PRIVIGEN": 114.08575290454652, "null": 2.720852107062384}
\ No newline at end of file
+{"COMIRNATY": 1.1071120040879086, "SPIKEVAX": 2.570001093044296, "VAXZEVRIA": 1.6355270955027947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7887.json
index 3c3433e5420..9f61d77a6cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7887.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7887.json
@@ -1 +1 @@
-{"CHAMPIX": 10.175205060162927, "OLANZAPINE": 25.30100663086496, "null": 1.7869125898115206}
\ No newline at end of file
+{"CELLCEPT": 3.220448691297732, "COMIRNATY": 3.000974436229587, "GARDASIL": 5.051379494696148, "KEYTRUDA": 1.5917341095834985, "SHINGRIX": 1.8151437892938311, "SIMPONI": 2.917147459895616, "SPIKEVAX": 0.9444771988213632, "TELMISARTAN": 29.142288020288525, "TOZINAMERAN": 0.6285462807381036, "TWINRIX": 16.771831940483228, "VAXZEVRIA": 1.0496268500707888, "null": 0.3690017075822371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7888.json
index 69d5f5bc476..fb7c75a4275 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7888.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7888.json
@@ -1 +1 @@
-{"null": 2.192150282390372}
\ No newline at end of file
+{"BUSULFAN": 4.222816641019078, "CELLCEPT": 3.3241551848852677, "COMIRNATY": 1.1651079811630811, "GARDASIL": 10.712938448215867, "SHINGRIX": 3.613059822671248, "SPIKEVAX": 1.0706252093540098, "TOZINAMERAN": 4.402168489167463, "TWINRIX": 11.48003730302966, "VAXZEVRIA": 2.404181031213981, "ZOSTAVAX": 5.733626457176317, "null": 0.2726488675380615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7889.json
index d0afae4ba5f..d22ea2347d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7889.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7889.json
@@ -1 +1 @@
-{"null": 1.4907411152407466}
\ No newline at end of file
+{"JAKAVI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/789.json
index f15b7cd7fa5..5d450a21e41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/789.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/789.json
@@ -1 +1 @@
-{"COMIRNATY": 2.1900734129944857}
\ No newline at end of file
+{"BRIVARACETAM": 53.10643467084547, "FYCOMPA": 37.00809436042189, "KEPPRA": 11.997395172019864, "LACOSAMIDE": 20.78181766814305, "LEVETIRACETAM": 12.941280590671036, "VIMPAT": 12.554149828038058, "null": 5.131479036170013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7890.json
index 1d3461169a6..2e15c88fcfb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7890.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7890.json
@@ -1 +1 @@
-{"SUTENT": 8.891895817495675, "null": 1.3072808816042267}
\ No newline at end of file
+{"null": 0.4504694085973649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7891.json
index e0c29e50c26..3ff106e8c7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7891.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7891.json
@@ -1 +1 @@
-{"CICLOSPORIN": 32.97253230584527, "METHOTREXATE": 58.27519382704307}
\ No newline at end of file
+{"MIDOSTAURIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7892.json
index 705d0363230..b226c408dc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7892.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7892.json
@@ -1 +1 @@
-{"KAFTRIO": 755.9659322881746}
\ No newline at end of file
+{"ABACAVIR": 0.5207070206544413, "ALEMTUZUMAB": 1.6957077528861602, "ALIMTA": 1.0619774653329954, "ARANESP": 11.956060322148296, "ARAVA": 0.1928063995384149, "AVASTIN": 1.2225915969761043, "AXICABTAGENE": 21.785252719774228, "AZACITIDINE": 20.665504242509662, "AZATHIOPRINE": 1.3433903443884574, "BEVACIZUMAB": 2.635720620967005, "BORTEZOMIB": 10.459418173903924, "BRUKINSA": 19.880619736329056, "BUSULFAN": 7.155838959002196, "CAELYX": 6.218518014670228, "CAPECITABINE": 4.499480231143266, "CARFILZOMIB": 5.278630910491181, "CARMUSTINE": 81.4027984094622, "CELLCEPT": 1.3423701812502582, "CHLORMETHINE": 134.23063423773536, "CICLOSPORIN": 4.761591367287479, "CLADRIBINE": 62.71173076078217, "COMIRNATY": 0.0576752882968285, "COSENTYX": 0.8881643683470568, "CYTARABINE": 16.599059698990477, "DECITABINE": 36.72531265495387, "DEXAMETHASONE": 6.353640531695741, "DOCETAXEL": 4.956878666132281, "DOXORUBICIN": 8.745734145159718, "ELIQUIS": 0.6096436369937266, "ENTRESTO": 0.8911213588645963, "EPOETIN": 12.66255227373563, "EVEROLIMUS": 4.7348508055082, "EXJADE": 33.35937060389989, "FILGRASTIM": 13.501437347217127, "FORSTEO": 0.7401592406308554, "HUMIRA": 0.6900200973027485, "IBRANCE": 0.319886382742326, "IRINOTECAN": 4.00334406871786, "JAKAVI": 2.0246731180673074, "JANUMET": 0.6914840203659757, "KEPPRA": 0.2976875695317607, "KEYTRUDA": 0.5888989457777424, "KYMRIAH": 5.44973197528824, "LANTUS": 0.3383216225905255, "LENALIDOMIDE": 13.012377022695713, "LUTATHERA": 18.3515893862464, "LUTETIUM": 114.05385490438854, "LYNPARZA": 66.9199319794156, "MABTHERA": 5.493830037244657, "MELPHALAN": 18.383451752961964, "MERCAPTOPURINE": 4.923730588694668, "METHOTREXATE": 2.371369981406714, "MIRCERA": 12.569013326754238, "NEULASTA": 2.5998930586428264, "NEXAVAR": 0.6059633297000243, "NOXAFIL": 11.827850148551256, "NPLATE": 45.83262020298119, "OLAPARIB": 84.74352439504008, "PEGASYS": 0.3629935710593597, "PEGINTRON": 0.7173338217258183, "PLAVIX": 1.0080910742612157, "RADIOTHERAPY": 76.19645250821675, "REVLIMID": 18.391103665090174, "RITUXIMAB": 7.526120802220703, "ROACTEMRA": 1.133947810968328, "RUBRACA": 8.928459387780606, "SIMPONI": 0.4140893930382814, "SOLIRIS": 9.820036981114429, "STELARA": 0.6958349336998546, "SUTENT": 0.1896390154866788, "TASIGNA": 2.225191691122253, "TEMODAL": 6.27015846392321, "TEMOZOLOMIDE": 32.27090725212073, "THALIDOMIDE": 6.728775349883188, "THIOTEPA": 13.236047168380043, "TOZINAMERAN": 0.0833389604252129, "VENETOCLAX": 9.761312109831897, "VFEND": 4.260659062728707, "XELJANZ": 0.5920211399791856, "XTANDI": 0.4927467948772953, "YESCARTA": 5.69639157441125, "ZEVALIN": 139.32337300908432, "null": 0.6774324194468203}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7893.json
index c7914487716..19f64a15b37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7893.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7893.json
@@ -1 +1 @@
-{"COVID19": 39.36730344655792, "TOZINAMERAN": 4.362207654457202}
\ No newline at end of file
+{"EXJADE": 477.023938774888, "null": 0.2079180229177799}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7894.json
index 87179dab4e6..998b768eef4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7894.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7894.json
@@ -1 +1 @@
-{"ABATACEPT": 4.964920347885803, "ADALIMUMAB": 3.6874795842126256, "ADCIRCA": 1.1469518708740665, "ADEMPAS": 1.0337686799327337, "ADVATE": 1.139761199358461, "ALDARA": 1.1955011066373464, "APREMILAST": 2.01257633174931, "ARAVA": 10.424636986412722, "BENLYSTA": 1.6641174460634525, "BONVIVA": 1.1353090725136952, "CELECOXIB": 1.2003933450046311, "CHLORHEXIDINE": 14.96385311638683, "CIMZIA": 5.527716011154509, "COMIRNATY": 1.0915050304638363, "CONTRAST": 2.127304036095246, "COSENTYX": 1.2964749924611003, "ENBREL": 2.0744617489509505, "ERELZI": 5.4602536472805605, "EXFORGE": 1.256913290122678, "FLUCELVAX": 1.7000863202306589, "GALAFOLD": 1.4238671782293986, "GALVUS": 1.100555231263744, "HEMLIBRA": 1.2588453274243168, "HIZENTRA": 1.7633232526771598, "HUMIRA": 1.5737080288438132, "HYQVIA": 1.5500083767721848, "INVEGA": 1.0445557226138211, "LEFLUNOMIDE": 1.3273911344636369, "LUPKYNIS": 1.5249809596557715, "MENVEO": 2.494978695153696, "METFORMIN": 1.674542243419121, "METHOTREXATE": 1.061101940133092, "NIMENRIX": 1.1459222300484122, "OMALIZUMAB": 1.00968664782804, "OPSUMIT": 1.464770713301869, "PIOGLITAZONE": 1.7612597605037104, "RUCONEST": 1.135196953872644, "SHINGRIX": 2.4234070669453565, "SPIKEVAX": 1.1837692418813233, "TOCOPHEROL": 4.8010335575525485, "TOUJEO": 1.0421287875219647, "TOZINAMERAN": 2.2537684987598663, "TWINRIX": 1.178636560914577, "XELJANZ": 1.436073498775894, "XOLAIR": 1.6831298081523398, "XYREM": 1.2699499059956494}
\ No newline at end of file
+{"CARMUSTINE": 187.05989123202315, "null": 0.5262498576795304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7895.json
index 546a8261bbb..59779543e97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7895.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7895.json
@@ -1 +1 @@
-{"AERIUS": 2.224771964737958, "BENLYSTA": 1.7197821141053975, "BETMIGA": 1.4974205544098678, "BEXSERO": 1.212416647401093, "BOCEPREVIR": 1.9940130196491517, "BONVIVA": 1.5371178702366926, "BOTULINUM": 23.827523545243032, "CHAMPIX": 1.405257844331244, "CINRYZE": 1.7469980974852504, "CLOFARABINE": 2.897593172655154, "COMIRNATY": 1.0039110943277336, "DELAMANID": 1.3047158622528277, "DESLORATADINE": 2.000409859292987, "ENTECAVIR": 2.182795241707037, "ENTRESTO": 2.654290262407296, "ERENUMAB": 2.5246848672073106, "EXFORGE": 2.593728764268929, "FASENRA": 1.7354246040192105, "FLUTICASONE": 8.34543516679287, "GALVUS": 1.6881272878240463, "HIZENTRA": 1.117047629846626, "HYDROCHLOROTHIAZIDE": 3.839674414283453, "INCIVO": 1.3181251003457068, "JANUVIA": 1.088799712445762, "KARVEA": 3.0261685818216084, "LOPINAVIR": 1.1575468006323606, "MENVEO": 1.4402495999251406, "MMRVAXPRO": 2.052452521328159, "NAGLAZYME": 1.1097041846037403, "NEULASTA": 1.404589936984413, "NEVANAC": 2.258173669718581, "NIMENRIX": 1.3704662239983274, "NORVIR": 1.1345260076185038, "OMALIZUMAB": 1.2000267792284098, "ONCASPAR": 3.591286846989186, "OSELTAMIVIR": 2.0656423248005717, "PREVENAR": 1.6522048505427192, "PRIVIGEN": 1.5246948419723485, "RANEXA": 1.573483481377983, "RASILEZ": 3.102168043210468, "RELVAR": 2.7047711913816075, "REYATAZ": 1.6524340735470424, "ROACTEMRA": 1.208840258926034, "SHINGRIX": 1.1846860421866712, "SILDENAFIL": 1.0898330642969285, "SUTENT": 1.7620180041607056, "TAMIFLU": 1.165851852786823, "TOVIAZ": 1.2007308812437858, "TOZINAMERAN": 1.9981772438158327, "TWINRIX": 1.5728737287386587, "VALSARTAN": 1.0379002480559096, "VIRAMUNE": 1.4712166286642945, "XOLAIR": 3.153603937995646, "ZELBORAF": 1.2143482381623794, "null": 1.6366035345122325}
\ No newline at end of file
+{"ARANESP": 75.16942991479918, "CELLCEPT": 13.752215515143051, "MIRCERA": 77.4415955149014, "RITUXIMAB": 21.13085046508849, "null": 0.6313956844240631}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7896.json
index e960df4c655..ada782464f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7896.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7896.json
@@ -1 +1 @@
-{"BETMIGA": 7.483972351985338, "BRIDION": 3.498537152878082, "CHAMPIX": 1.1844220387888802, "COMIRNATY": 1.174797011258235, "EYLEA": 4.114859367495336, "IKERVIS": 40.99568776187496, "MMRVAXPRO": 1.1432360068236933, "NEVANAC": 17.288658040971523, "NIMENRIX": 1.8433223967594483, "NUCALA": 1.2641530203015856, "SHINGRIX": 1.0528826619786658, "SUTENT": 1.6576054760456336, "TAMIFLU": 1.022366225432736, "TOZINAMERAN": 1.5765652600389082, "XOLAIR": 2.02944239045929, "null": 1.7518444363300891}
\ No newline at end of file
+{"ANAGRELIDE": 245.4323693937629, "ARANESP": 2.8829862344137127, "BUSULFAN": 6.324660709601141, "EXJADE": 18.718076744532823, "JAKAVI": 325.649488032203, "NPLATE": 172.97106796132394, "PEGASYS": 0.776392725654322, "RUXOLITINIB": 150.31914257748258, "null": 0.8475032648632534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7897.json
index b998900e2b9..d0b2d2799d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7897.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7897.json
@@ -1 +1 @@
-{"COSENTYX": 193.90144038620733}
\ No newline at end of file
+{"CICLOSPORIN": 9.007836703090796, "DASATINIB": 138.31933612043383, "null": 1.4359909872482937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7898.json
index 1cf39224876..c079965f928 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7898.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7898.json
@@ -1 +1 @@
-{"ENBREL": 664.4925987928443}
\ No newline at end of file
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7899.json
index 1a12eb62d5a..adea616a844 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7899.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7899.json
@@ -1 +1 @@
-{"ABATACEPT": 19.69115961061168, "ADALIMUMAB": 25.49882592969712, "APREMILAST": 130.637047524376, "ARAVA": 49.96763288366297, "CIMZIA": 5.767018948790028, "COSENTYX": 6.280970407557677, "HUMIRA": 8.157357656832843}
\ No newline at end of file
+{"null": 1.6086976435080844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/79.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/79.json
index 35b0baa8ea8..20c5631c5b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/79.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/79.json
@@ -1 +1 @@
-{"ACTRAPID": 4.187485096400902, "AERIUS": 3.019200393850785, "APIDRA": 2.167754391955064, "BENZODIAZEPINE": 5.519445121223284, "BENZODIAZEPINES": 14.4873249797832, "BRINTELLIX": 1.0729290197377412, "BUPIVACAINE": 1.1543149929995729, "BUPRENORPHINE": 6.53919443231089, "COAPROVEL": 2.514865300231997, "DULOXETINE": 3.073563277539737, "EBIXA": 8.563238953198683, "EPCLUSA": 1.567735324059847, "ESOMEPRAZOLE": 1.7664279745763598, "FENTANYL": 7.2996733370029565, "FIASP": 2.3082973785057344, "FORSTEO": 2.263475022174904, "FYCOMPA": 3.253932905014447, "GLIBENCLAMIDE": 6.221685489167692, "GLUCAGON": 5.725508664208805, "HUMALOG": 1.2150245940807594, "IBUPROFEN": 3.704540287481164, "INSULIN": 2.101898190525938, "JEVTANA": 2.726638118135794, "KALETRA": 2.016891151012745, "KEPPRA": 2.666038507763053, "LANTUS": 2.804114591425124, "LATUDA": 1.223094653374395, "LEVEMIR": 2.731468809454636, "LEVETIRACETAM": 1.9455989874015305, "LEVODOPA": 2.822563514884808, "MELATONIN": 2.9186202413734117, "MIDAZOLAM": 3.2772688344760272, "MOVYMIA": 10.739194637913451, "NOT": 1.5515672150577402, "NOVORAPID": 2.494252812938781, "NOXAFIL": 1.608354093609624, "OLANZAPINE": 3.273911711555235, "OLYSIO": 1.30296757733378, "OPIOIDS": 16.81550769169097, "OXYBUTYNIN": 7.830287933504132, "PREGABALIN": 11.227251486781157, "PROPRANOLOL": 2.432886351274688, "RELVAR": 1.811954059446731, "SUBOXONE": 3.906873276587887, "TAMIFLU": 1.2714277274332255, "TEMODAL": 2.02270447511109, "TOVIAZ": 1.073572798633467, "TRESIBA": 2.6296123090845573, "TRULICITY": 2.658208553952218, "TWINRIX": 1.356402867380287, "VFEND": 1.013658156478193, "VIAGRA": 1.1366848369636366, "VICTOZA": 1.249556129318313, "VIMPAT": 1.6645113739010615, "XYREM": 1.3005724455223069, "ZYPREXA": 2.174367119340546, "null": 4.627073048447862}
\ No newline at end of file
+{"null": 2.438189529570985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/790.json
index f8a2ceca2de..8f855fbe852 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/790.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/790.json
@@ -1 +1 @@
-{"COMIRNATY": 4.831571464584694, "SPIKEVAX": 3.713326017239901, "TOZINAMERAN": 6.908733209412334}
\ No newline at end of file
+{"DULOXETINE": 167.74171707548206, "null": 3.633772074305547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7900.json
index 7dfffd7c6ed..4cf850a50ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7900.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7900.json
@@ -1 +1 @@
-{"AFINITOR": 1.3971115664171143, "BETMIGA": 2.2244958654832154, "BOTULINUM": 42.79880261636546, "CELECOXIB": 1.389158153083344, "CHAMPIX": 1.7013417612552535, "CLOPIDOGREL": 1.1366065293064258, "DESLORATADINE": 2.7625054080265263, "ENTRESTO": 3.5034004295996666, "EXFORGE": 1.976091173571463, "FASENRA": 1.6401091311812168, "HIZENTRA": 1.428626443936574, "IBUPROFEN": 1.1102377279184734, "INCRUSE": 1.496121039929445, "IRBESARTAN": 3.1750382884388038, "LATUDA": 3.63075821030564, "MICARDIS": 1.5233789095401544, "NEULASTA": 1.8887316681284927, "NIMENRIX": 1.0867736836479762, "OMALIZUMAB": 1.758889490711822, "OXYBUTYNIN": 2.2422094983519347, "PRIVIGEN": 1.448019746112332, "PROTELOS": 4.309605731693081, "RASILEZ": 3.0068297554335097, "RELVAR": 1.3308723993764813, "SUBOXONE": 2.311872305778017, "TAMIFLU": 1.1065066314961507, "TICAGRELOR": 1.095320298518027, "TOUJEO": 1.0308991742369709, "TOVIAZ": 2.633845946699353, "TOZINAMERAN": 2.047366949116115, "XOLAIR": 3.8450131494927584, "null": 2.116307865719181}
\ No newline at end of file
+{"ASPARAGINASE": 12.887382671684607, "BUPRENORPHINE": 6.320126074017229, "COMIRNATY": 0.5275857660123157, "CYTARABINE": 15.337413912491414, "NAGLAZYME": 35.243267916551126, "SPIKEVAX": 0.2105323503023155, "VAXZEVRIA": 0.3811673559277876, "ZOSTAVAX": 7.27424821666292, "null": 0.934777390589595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7901.json
index dba9a989117..c32313844d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7901.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7901.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 449.1255590127831}
\ No newline at end of file
+{"COMIRNATY": 0.1233509560661745, "JAKAVI": 38.98554006133119, "NPLATE": 33.1015936978901, "null": 1.0856945701394936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7902.json
index 204eccbb73e..e6a3c4aa990 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7902.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7902.json
@@ -1 +1 @@
-{"null": 1.5302196860678896}
\ No newline at end of file
+{"ABEMACICLIB": 20.66017116223991, "ABRAXANE": 5.778864293248316, "ADCETRIS": 5.235131906938769, "AFINITOR": 0.4305540963819965, "ALEMTUZUMAB": 0.3145579297345217, "ALIMTA": 8.335613859382482, "AMIKACIN": 1.3602530956795982, "ANAKINRA": 0.2695704422813916, "ARANESP": 0.471825929791546, "ARAVA": 0.0727477486973839, "ASPARAGINASE": 3.414780689926144, "ATEZOLIZUMAB": 1.1625793726148, "AVASTIN": 9.366692136196528, "AXICABTAGENE": 4.29364959033556, "AZACITIDINE": 28.384324838937022, "AZATHIOPRINE": 0.8985149344821769, "BASILIXIMAB": 0.7724969027476167, "BEDAQUILINE": 0.7783748215742257, "BEVACIZUMAB": 18.716541768337738, "BLINCYTO": 4.683653799613817, "BORTEZOMIB": 5.9212924305736, "BRENTUXIMAB": 15.995376106483372, "BRUKINSA": 22.305217271544183, "BUDESONIDE": 0.2355524420257015, "BUSULFAN": 3.4424886231941407, "CABOMETYX": 0.3902030976479084, "CAELYX": 1.4458311507280508, "CANCIDAS": 0.8273622351350062, "CAPECITABINE": 28.28382684720369, "CARFILZOMIB": 5.191808359462111, "CARMUSTINE": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7903.json
index 30ae1ed0b19..fa63acb3950 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7903.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7903.json
@@ -1 +1 @@
-{"BUPIVACAINE": 71.44799938243642, "PANTOPRAZOLE": 36.53741958684044, "null": 3.3492101612946694}
\ No newline at end of file
+{"null": 1.3183814393892817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7904.json
index eb384e8b818..a00c5ce4e60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7904.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7904.json
@@ -1 +1 @@
-{"null": 2.8576095853763683}
\ No newline at end of file
+{"null": 1.3080303508864288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7905.json
index b5a97adba48..bf67ab6cf2f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7905.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7905.json
@@ -1 +1 @@
-{"null": 2.1328766063100795}
\ No newline at end of file
+{"null": 3.794122163064106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7906.json
index 53e8709174e..3a5e0b986ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7906.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7906.json
@@ -1 +1 @@
-{"ABILIFY": 14.386164822575331, "ACLIDINIUM": 75.6748400105427, "BENLYSTA": 7.714755378697043, "CICLOSPORIN": 2.9553198714604143, "COSENTYX": 9.20038656979777, "FASENRA": 18.220197870284245, "MEPOLIZUMAB": 15.577538721492443, "NUCALA": 4.96630252462112, "SOLIRIS": 8.449623123579581, "XELJANZ": 1.852482390942486, "XOLAIR": 3.3462164605735776, "null": 1.165020697336015}
\ No newline at end of file
+{"COMIRNATY": 0.7607783505010373, "OPTIMARK": 11.17510169807368, "SOMATROPIN": 99.93713553370924, "SPIKEVAX": 0.3409028740810554, "TESTOSTERONE": 91.75883416578648, "TOZINAMERAN": 0.8330453209769991, "null": 1.3962097367664776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7907.json
index f76d48fe064..cb0e9061823 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7907.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7907.json
@@ -1 +1 @@
-{"ACLASTA": 1.480916779339059, "ADCIRCA": 2.654082870601928, "ADEMPAS": 1.1233852025152449, "AMBIRIX": 4.986117072753408, "AMBRISENTAN": 1.697304849237485, "ANAKINRA": 2.257386136910581, "AXURA": 3.516029121483036, "BETA": 2.87167496675773, "BETMIGA": 1.0862843690324553, "BEXSERO": 3.7714220368277056, "BLINDED": 3.374167327461674, "BOSENTAN": 1.1098046569015272, "BRILIQUE": 1.1600834610781523, "BUMETANIDE": 1.1134234057669132, "CABOTEGRAVIR": 1.1933576994691617, "CERVARIX": 4.246273962058561, "COAPROVEL": 2.074356053283523, "COMIRNATY": 1.7151090148564776, "CYMBALTA": 1.13818636649589, "DACLATASVIR": 1.099818727966889, "DESLORATADINE": 1.2978973154077669, "EBIXA": 2.8472773460302787, "EDOXABAN": 3.1538023199180003, "EMPAGLIFLOZIN": 1.5132908634760869, "ENTRESTO": 1.887158737837276, "ENZALUTAMIDE": 1.063409593402582, "EXELON": 3.38005165759865, "EXFORGE": 1.6663237986456612, "FESOTERODINE": 2.217014829431105, "FLUCELVAX": 2.014654238470554, "FORSTEO": 1.704440010728188, "GALAFOLD": 1.2884758403167238, "GARDASIL": 10.00299991856321, "GAZYVARO": 1.0682947607074231, "HYDROCHLOROTHIAZIDE": 1.6200943156071823, "INCIVO": 1.0216382884887265, "IRBESARTAN": 1.9626690613486757, "IVABRADINE": 1.8276965009713853, "KARVEA": 2.7685604600654976, "KARVEZIDE": 4.962151924045536, "LANTUS": 1.0972207127811449, "MACITENTAN": 2.602529832754711, "MEMANTINE": 2.218647255873932, "MENVEO": 7.617114594183518, "MICARDIS": 2.355347912472822, "MICARDISPLUS": 4.372505665074195, "MMRVAXPRO": 1.8306183760120056, "NEVIRAPINE": 1.5965592447278154, "NIMENRIX": 4.397559999885228, "OPSUMIT": 1.370640585454769, "PEGINTRON": 1.0068491505298172, "PRITOR": 5.539313156083034, "PRITORPLUS": 5.122572817708822, "PROCORALAN": 3.134605532039512, "PROTELOS": 1.1180157888479745, "RANEXA": 2.7894655454613, "RANOLAZINE": 2.532811778438509, "RAPISCAN": 1.3992518224183477, "RASILEZ": 1.2887172191432787, "REBLOZYL": 2.328231048312288, "RIVAROXABAN": 1.325901866955428, "ROTARIX": 1.9133444768721677, "SAXENDA": 1.0544625002658925, "SHINGRIX": 1.3704010721755544, "SIFROL": 1.2028755176328878, "SILDENAFIL": 1.737774231546547, "SILGARD": 5.987060720644636, "SILODOSIN": 6.065066819576177, "SILODYX": 2.8974743140765757, "SPIKEVAX": 1.4439563238736983, "SPIRONOLACTONE": 1.901979180142508, "SYCREST": 1.9954131749875692, "TAFAMIDIS": 8.648635389357425, "TELMISARTAN": 1.628775432939941, "THALIDOMIDE": 1.0500193300660936, "TOZINAMERAN": 2.34793687396068, "TRACLEER": 1.717138538432074, "TRUMENBA": 22.356515565132643, "TWINRIX": 2.440598302052053, "UROREC": 3.7727396840651055, "VALSARTAN": 1.3963631719016814, "VIAGRA": 1.55879747946249, "VILDAGLIPTIN": 4.616278790280124, "ZARZIO": 2.198306704776937, "ZYPADHERA": 1.3570792890456058, "null": 1.0801547541775034}
\ No newline at end of file
+{"null": 2.048058036459657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7908.json
index 1ccbe4e3bcb..b7ffc5fe250 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7908.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7908.json
@@ -1 +1 @@
-{"METHOTREXATE": 6.558981165985358, "null": 3.971983335530452}
\ No newline at end of file
+{"OLANZAPINE": 254.2160090242065}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7909.json
index 752d9e92b2b..f33abc94672 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7909.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7909.json
@@ -1 +1 @@
-{"null": 2.792889305099717}
\ No newline at end of file
+{"ABACAVIR": 0.411449650941697, "ABATACEPT": 0.0766803477268375, "ABILIFY": 0.1617607487803676, "ACLIDINIUM": 0.3260738696486999, "ACTOS": 3.595675451737431, "ACTRAPID": 0.4007924324815847, "ADALIMUMAB": 0.007952652968288, "ADENURIC": 0.5138531801962358, "AFINITOR": 0.2485922558861077, "AIMOVIG": 0.5023284611633684, "ALIMTA": 0.6808244299440432, "ALL": 1.0103782163845956, "AMINOSALICYLIC": 0.1251045040482792, "ANAKINRA": 2.4768689686663907, "ANGIOX": 4.128972686019072, "ANORO": 1.026733227169148, "APIDRA": 1.3459384792823883, "APIXABAN": 1.2208838035937413, "APROVEL": 1.0739396042907712, "ARANESP": 0.8326000376437646, "ARAVA": 0.1539254323398463, "ARIPIPRAZOLE": 0.0997066941064166, "ATAZANAVIR": 0.581427431126191, "ATRIPLA": 0.0389753316406939, "AUBAGIO": 0.8959164896091473, "AVANDAMET": 63.61789877734254, "AVANDIA": 65.88708404164942, "AVASTIN": 1.1257924317278707, "AXITINIB": 0.7219915523533518, "AZATHIOPRINE": 0.3333124101392818, "BARACLUDE": 0.6280990257708088, "BEDAQUILINE": 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3.3306492376912646, "HUMAN": 0.7400466979102694, "HUMIRA": 0.5988583640356007, "HYDROCORTISONE": 0.6207900227273205, "IBRANCE": 0.4897347549293726, "IBUPROFEN": 0.3334290154805485, "ICLUSIG": 3.066776604543855, "INCIVO": 0.2301606691412675, "INCRUSE": 1.6410064266788165, "INLYTA": 1.6702540268137929, "INSULIN": 1.5383403274772414, "INTEGRILIN": 6.57120765111645, "INTELENCE": 2.15311431672718, "INTRONA": 0.9202950157499769, "INVIRASE": 3.1964369748732766, "INVOKANA": 2.8731209675729468, "IRBESARTAN": 0.2807052754773363, "IRESSA": 0.5336401680165169, "ISENTRESS": 1.546848265925182, "JAKAVI": 0.4459739407648261, "JANUMET": 2.9149092855906016, "JANUVIA": 1.966709934616422, "JARDIANCE": 3.6087764965702656, "JEVTANA": 0.5550290637568593, "KAFTRIO": 0.3578353992873698, "KALETRA": 0.9699947376014144, "KEPPRA": 0.2543358096578359, "KEYTRUDA": 0.3263136588943338, "KIOVIG": 0.4278574498399454, "KISQALI": 0.3347010710378418, "KIVEXA": 3.8757845799855386, "KYPROLIS": 2.52365714068476, "LANTUS": 2.813897353398126, "LATUDA": 0.5509303674290944, "LEMTRADA": 0.2973152737155198, "LENVIMA": 1.131892114555722, "LEVEMIR": 2.7523365090686305, "LEVETIRACETAM": 0.0549712885442458, "LEVOFLOXACIN": 0.3936456796211849, "LONSURF": 0.2020177575476709, "LYRICA": 0.9267093042619792, "MABTHERA": 0.245826773263686, "MEKINIST": 0.3389910138424777, "MEMANTINE": 1.2318782225499905, "MEPOLIZUMAB": 0.1623096624512156, "METHOTREXATE": 0.2410882017989531, "MICARDIS": 2.296668461155902, "MICARDISPLUS": 1.9083175298487525, "MIDAZOLAM": 0.1989605437209669, "MIMPARA": 0.8061551597839085, "MIRCERA": 1.4524623029447965, "MIXTARD": 1.797985295253249, "MODERNA": 0.0838354163201579, "MULTAQ": 0.527466415133206, "NEULASTA": 0.2790571227793401, "NEXAVAR": 1.2486917047344328, "NILOTINIB": 2.908153651936296, "NINLARO": 0.492565049465752, "NORVIR": 1.576507284058333, "NOT": 0.7187689596392658, "NOVONORM": 0.9181357698640876, "NOVORAPID": 0.4740950541933864, "NOVOSEVEN": 5.689921343228859, "NOXAFIL": 0.3065166117842579, "NPLATE": 1.2799854182875714, "NUCALA": 0.1730843151942893, "OCALIVA": 0.5795503070333752, "OCRELIZUMAB": 0.142984138974148, "OFEV": 2.170622258264545, "OLANZAPINE": 0.1788196549467826, "OLYSIO": 0.4524563941972213, "OMALIZUMAB": 0.2658126582162577, "ONGLYZA": 6.590586636395497, "OPDIVO": 0.1828950199992163, "OPSUMIT": 0.5395338910264713, "OPTIMARK": 0.1415704629797318, "PACLITAXEL": 0.2957342053511155, "PANTOPRAZOLE": 0.6074289684523367, "PEGASYS": 0.8294971320814286, "PEGINTERFERON": 0.3618508975665978, "PEGINTRON": 0.6272352742638573, "PEMBROLIZUMAB": 0.1515701394090512, "PLAVIX": 5.374493988910676, "PLEGRIDY": 0.5074675014263501, "PRADAXA": 0.751030705729487, "PRASUGREL": 2.8012780644058526, "PREGABALIN": 0.5708151770517595, "PRIVIGEN": 0.2177175788462035, "PROTELOS": 0.8768466357244051, "RANEXA": 0.8109666112153477, "RANOLAZINE": 6.369605078928369, "RAPAMUNE": 1.5311539873087836, "RASILEZ": 0.887505639258223, "REBETOL": 0.6193125062314655, "RELVAR": 0.2238967268570851, "REMICADE": 0.2302480243755116, "REVATIO": 1.97455799136926, "REVLIMID": 0.6965874276143896, "REYATAZ": 0.898551102087435, "RIBAVIRIN": 0.6616398660770741, "RINVOQ": 1.5269007023698735, "RITUXIMAB": 0.4151360584064381, "ROACTEMRA": 1.0441520418853367, "ROSIGLITAZONE": 45.30991079890095, "RYBELSUS": 0.6970787791492806, "SAXENDA": 0.2240072490167871, "SHINGRIX": 0.0701065801033067, "SIFROL": 0.4678131928572313, "SILDENAFIL": 1.5394319865870238, "SIMPONI": 1.0268042073661874, "SKYRIZI": 1.8025082236235224, "SOLIRIS": 0.4387493708227314, "SOMATROPIN": 0.815505401002395, "SORAFENIB": 0.6548675746873394, "SOVALDI": 1.1503085306016425, "SPIKEVAX": 0.2462679596677002, "SPIRONOLACTONE": 0.8387452518772617, "SPRYCEL": 1.483798901168217, "STALEVO": 0.5299662864503271, "STELARA": 2.120741096672489, "STIVARGA": 0.5570442763338744, "STRIBILD": 0.1732058681165759, "SUBOXONE": 0.7243856817036499, "SUFENTANIL": 0.4135849709413298, "SUTENT": 0.925436009096526, "SYMTUZA": 1.7178159104733677, "TAGRISSO": 0.6430465289486447, "TAMIFLU": 0.1764030925713257, "TASIGNA": 4.503051515932873, "TEMSIROLIMUS": 4.519647519580414, "TERIPARATIDE": 1.2059726310213024, "TESTOSTERONE": 4.292764777491754, "THALIDOMIDE": 0.9005434597201641, "TICAGRELOR": 0.9094652284895586, "TIVICAY": 0.7039660934152993, "TOCILIZUMAB": 0.7084981592316136, "TORISEL": 0.6251412248269148, "TOUJEO": 1.8303165043837413, "TOVIAZ": 0.4168326900072491, "TOZINAMERAN": 0.6537551229102446, "TRACLEER": 1.0192593604773732, "TRELEGY": 3.23695414779638, "TREMFYA": 1.591380937462406, "TRIUMEQ": 4.083600852210179, "TRULICITY": 1.345807761506366, "TRUVADA": 0.0477082934093766, "VALSARTAN": 0.9371663791684892, "VAXZEVRIA": 0.2201540981591027, "VELTASSA": 2.7420414028758637, "VFEND": 0.357323271489252, "VIAGRA": 5.754736676708825, "VICTOZA": 1.0223868188957252, "VIMPAT": 0.3170309018406282, "VIRAMUNE": 0.8483262649434642, "VIREAD": 0.2594450247115718, "VOTRIENT": 1.254544240519241, "XALKORI": 0.413958933570457, "XARELTO": 1.3386604515440417, "XELJANZ": 1.3230765853523083, "XELODA": 0.567902659725079, "XOLAIR": 1.1095180648124972, "XTANDI": 1.2708218152975992, "YERVOY": 0.3103734254026036, "ZELBORAF": 0.2679739004241012, "ZIAGEN": 1.2999276197544107, "ZOSTAVAX": 0.6798154838625142, "ZYPREXA": 1.3098376515529386, "null": 1.228640647510675}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/791.json
index dddf2576712..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/791.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/791.json
@@ -1 +1 @@
-{"COMIRNATY": 7.516416794400517, "COVID19": 1.0701628816446875, "NIMENRIX": 1.9583965863177084, "SPIKEVAX": 4.556141088834684, "TOZINAMERAN": 5.699361494038049}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7910.json
index f8e2d7e097d..f68638b9c9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7910.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7910.json
@@ -1 +1 @@
-{"ANAKINRA": 8.61115687772726, "ARAVA": 3.8386537542175647, "BUDESONIDE": 2.099130133272767, "CIMZIA": 1.4705879738141148, "COSENTYX": 4.07387817867366, "HARVONI": 10.089949488553408, "IBRANCE": 1.53769180063044, "IBUPROFEN": 5.28546708989836, "LEFLUNOMIDE": 12.2626082122909, "OZEMPIC": 37.67093384264987, "SIMPONI": 3.7724115050502194, "XELJANZ": 7.054134386319614, "ZOSTAVAX": 6.313474926924271}
\ No newline at end of file
+{"AVANDAMET": 147.73120757729404, "AVANDIA": 181.7509825862903, "COMIRNATY": 0.239596092847011, "KEYTRUDA": 1.3924494733047812, "ROTATEQ": 11.973287805411006, "SPIKEVAX": 0.593340783029504, "TOZINAMERAN": 2.322286854540389, "VAXZEVRIA": 0.2093514788808748, "null": 0.5089078988261373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7911.json
index 8c7439edfe0..5d878d4afa6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7911.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7911.json
@@ -1 +1 @@
-{"ARAVA": 2.495526998722089, "COSENTYX": 20.44162869518447, "EMPAGLIFLOZIN": 192.74945276491692, "ENBREL": 32.99205075254639}
\ No newline at end of file
+{"ABACAVIR": 0.5534760512188631, "AMINOSALICYLIC": 2.2842172773270764, "ARAVA": 0.2622679613684968, "AVANDAMET": 105.0980192728626, "AVANDIA": 75.73261401072858, "AVASTIN": 2.7681140943468563, "AZACITIDINE": 4.443949324395582, "AZATHIOPRINE": 1.2609557439886416, "AZILECT": 14.943365240846106, "BEDAQUILINE": 5.316367139528253, "BRILIQUE": 2.2240456155765203, "BUPRENORPHINE": 0.8853602826007575, "BYETTA": 0.789267968031691, "CELLCEPT": 0.8012695186477987, "CHAMPIX": 0.6224859950159183, "CICLOSPORIN": 0.5015855800249366, "CLOPIDOGREL": 2.6668490283279875, "COMIRNATY": 0.2439762415775813, "CYMBALTA": 0.468192370491754, "DASATINIB": 33.602464866388445, "ELIQUIS": 0.5065297431931405, "EMEND": 6.862248400903142, "ENTRESTO": 2.1172057876936594, "ENTYVIO": 1.139134793521046, "ENVARSUS": 67.86487204535443, "EXJADE": 0.6791251360644219, "FENTANYL": 3.345072898037935, "IBUPROFEN": 1.08581101133487, "ICLUSIG": 6.990298694124772, "JAKAVI": 1.7397012126919404, "JARDIANCE": 0.475524635553333, "KEYTRUDA": 0.5124244828793889, "KYPROLIS": 4.063369566035392, "LEVOFLOXACIN": 1.15976463832387, "MICARDIS": 1.4307093618609728, "NEXAVAR": 2.83048811523868, "NILOTINIB": 14.560143763627284, "NOVOSEVEN": 6.970902287729764, "OLANZAPINE": 0.4977223670097925, "PEGASYS": 0.575616457805488, "PEGINTRON": 0.5978922915279993, "PLAVIX": 1.5442292830897986, "RITUXIMAB": 1.455658191509928, "ROSIGLITAZONE": 23.74918556953053, "SPIKEVAX": 0.1488620738598222, "STIVARGA": 1.5864065949032315, "SUTENT": 0.622755718654508, "TASIGNA": 8.117089601181158, "TOZINAMERAN": 0.2337525888336406, "TRACLEER": 0.9310173188188392, "VAXZEVRIA": 0.1731509167694037, "VOTRIENT": 1.058041976108219, "XOLAIR": 0.449849582942967, "XTANDI": 0.8077625186144248, "ZOSTAVAX": 0.8329167174673585, "ZYPREXA": 1.0690472552001569, "null": 0.9622624366124878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7912.json
index bbc7289cf60..ffa948afa23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7912.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7912.json
@@ -1 +1 @@
-{"null": 7.228054958425599}
\ No newline at end of file
+{"COMIRNATY": 0.5664127825272758, "null": 1.2093357789939485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7913.json
index 031785b5b26..1ee20593d39 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7913.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7913.json
@@ -1 +1 @@
-{"null": 1.0786987957213037}
\ No newline at end of file
+{"CLOPIDOGREL": 6.6695769703259735, "COMIRNATY": 0.7560187489133399, "KEYTRUDA": 3.077537087033547, "PEGASYS": 0.891450526251462, "SPIKEVAX": 0.3099293705791469, "SUTENT": 1.20035994857248, "TOZINAMERAN": 0.8494264492126451, "null": 1.334093817496607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7914.json
index be82df7323c..cb9cc0ad79b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7914.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7914.json
@@ -1 +1 @@
-{"ABATACEPT": 10.257744862955487, "ADALIMUMAB": 10.90125229090614, "AMGEVITA": 50.74562628472639, "ANAKINRA": 13.943260613063604, "APREMILAST": 4.9177431661289726, "ARAVA": 41.80207348107168, "ARIPIPRAZOLE": 1.1435568934328797, "AZATHIOPRINE": 4.107474104897267, "BUDESONIDE": 1.0763236991394856, "CERTOLIZUMAB": 16.266676474083628, "CICLOSPORIN": 1.9374151628192304, "CIMZIA": 13.66204840752829, "COSENTYX": 6.595041069634799, "EMPAGLIFLOZIN": 2.824049319653149, "ENBREL": 29.59091849214458, "ERELZI": 35.37116521069708, "ETANERCEPT": 7.351519167574231, "HUMIRA": 12.420267993527448, "LEFLUNOMIDE": 14.314795731591746, "METHOTREXATE": 4.439000049782897, "RINVOQ": 4.321514368197263, "RITUXIMAB": 2.6140392681667413, "XELJANZ": 2.197546493024581}
\ No newline at end of file
+{"COMIRNATY": 0.731048064769214, "ERENUMAB": 248.40339966835413, "SPIKEVAX": 1.504731154982161, "TOZINAMERAN": 2.7008779523353525, "null": 0.6545238090411333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7915.json
index d84244efa3e..619ffe84c65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7915.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7915.json
@@ -1 +1 @@
-{"ATRIPLA": 1.731484058097156, "BIKTARVY": 36.58830183238787, "DESCOVY": 116.42312442563582, "SIMPONI": 8.450840284203936, "TRUVADA": 4.282063284253092}
\ No newline at end of file
+{"OLANZAPINE": 397.1334500894946}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7916.json
index 1e747905bae..c1c4b2022f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7916.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7916.json
@@ -1 +1 @@
-{"AIMOVIG": 7.012782889014786, "CIMZIA": 4.412264864128447, "COSENTYX": 2.7156098018006425, "DUPIXENT": 37.55296402332177, "EYLEA": 28.849546223776585, "MENVEO": 17.302810662372657, "MMRVAXPRO": 4.106476847441487, "ROACTEMRA": 11.570149793157396, "SIMPONI": 22.95396747525637, "SOMAVERT": 158.79809861795198, "STELARA": 71.35382302501024, "TREMFYA": 36.81146975776439, "TWINRIX": 9.7562749112094, "XOLAIR": 4.5638630696758895, "null": 1.279092394204662}
\ No newline at end of file
+{"COMIRNATY": 0.6107403037684705, "SILDENAFIL": 98.5891662373671, "null": 1.1702491347304853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7917.json
index 66dd86e4f5d..03b197e37fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7917.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7917.json
@@ -1 +1 @@
-{"CELECOXIB": 124.53901351863097, "null": 1.3444230548771494}
\ No newline at end of file
+{"SPIKEVAX": 1.1586023139858832, "VAXZEVRIA": 5.046755784132367, "null": 0.1948912636566993}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7918.json
index 04f83c0802b..42e252a8119 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7918.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7918.json
@@ -1 +1 @@
-{"null": 2.119843710264686}
\ No newline at end of file
+{"null": 10.785281122358723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7919.json
index 7f332404521..7ac9fed6177 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7919.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7919.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 11.10772666084696, "AMIKACIN": 44.04506161520125, "ASPARAGINASE": 9.784858006065411, "AZACITIDINE": 26.5420189444426, "BEVACIZUMAB": 7.633130533655028, "BUSULFAN": 11.372327522008648, "CANCIDAS": 44.726845426116746, "CASPOFUNGIN": 100.571596874052, "CICLOSPORIN": 7.609906660909628, "CUBICIN": 12.551754928045783, "CYTARABINE": 16.958757636291455, "DEXAMETHASONE": 6.78452591572543, "ECULIZUMAB": 218.76541966221316, "FORXIGA": 6.997512362771251, "JARDIANCE": 6.174864984212487, "NOXAFIL": 33.47062391872174, "VORICONAZOLE": 26.521956508645875, "YESCARTA": 15.470756552538058}
\ No newline at end of file
+{"ABILIFY": 0.3405478434699906, "ALIMTA": 0.3170566018919492, "ARAVA": 0.021331346335226, "ARIPIPRAZOLE": 2.110092669167389, "AVANDIA": 0.1043447786443657, "AVELUMAB": 6.266588365811183, "AXITINIB": 2.9592380274296097, "BAVENCIO": 7.7464849406626, "BEVACIZUMAB": 0.2753156447490295, "BUSILVEX": 8.446375965893624, "CABOMETYX": 0.5819920338565936, "CHAMPIX": 0.1968436151344171, "CICLOSPORIN": 0.1836111611561076, "COMIRNATY": 6.12114765443157, "COTELLIC": 0.8919635365858373, "DASATINIB": 1.904213315640024, "ENTRESTO": 0.2098789315807916, "ENTYVIO": 0.4203339888689209, "FYCOMPA": 1.244473084836656, "GARDASIL": 0.17281981274983, "IBUPROFEN": 0.2406560245144042, "INLYTA": 0.4459633594193956, "IPILIMUMAB": 8.622128064118565, "KEYTRUDA": 6.14896135494254, "LENVIMA": 0.5100101477558563, "LEVETIRACETAM": 0.2446786038512322, "LIBTAYO": 6.679995533611112, "LURASIDONE": 5.952689749045105, "MODERNA": 2.2646730302435576, "NIMENRIX": 0.8589962833873063, "NIVOLUMAB": 2.253765564560521, "OLANZAPINE": 1.594663596021577, "OPDIVO": 6.062662293770092, "PALIPERIDONE": 6.188728971692331, "PEGASYS": 0.1519341685863854, "PEMBROLIZUMAB": 5.850787012379521, "POTELIGEO": 7.022884251373756, "RINVOQ": 0.2495496002754653, "ROACTEMRA": 0.4447577434561761, "SHINGRIX": 0.1712683904423767, "SIMPONI": 0.1504276750461631, "SPIKEVAX": 3.291475245389768, "STELARA": 0.2912495983419018, "TAGRISSO": 0.6262037361744098, "TAMIFLU": 1.2946567826913036, "TOCILIZUMAB": 1.3274701269178066, "TOZINAMERAN": 4.344279192789194, "VALSARTAN": 1.146167137627587, "VAXZEVRIA": 0.3883255291742787, "XOLAIR": 0.1817717355529023, "YERVOY": 1.0906946755866085, "ZYPREXA": 0.1167783562906269, "null": 0.1701196151416206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/792.json
index a49326a6190..c63306ba56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/792.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/792.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2017143785912765, "VAXZEVRIA": 1.5609487405581597}
\ No newline at end of file
+{"ABILIFY": 66.58510370857897, "null": 3.964240603373168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7920.json
index 26fdc0cb698..cd238ae8376 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7920.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7920.json
@@ -1 +1 @@
-{"KEPPRA": 6.314935411712529, "null": 1.1963761136891635}
\ No newline at end of file
+{"BASILIXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7921.json
index c33f1a676cd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7921.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7921.json
@@ -1 +1 @@
-{"BUSULFAN": 4.754218232193952, "CELLCEPT": 2.7147943317151264, "CICLOSPORIN": 1.1004192020419297, "CLOPIDOGREL": 2.806224503145955, "COTELLIC": 12.000473504775988, "CUBICIN": 8.867362060286055, "CYTARABINE": 3.004391599369833, "INSULIN": 3.1079166677180976, "INVOKANA": 30.685230243135727, "JARDIANCE": 1.6080389563156423, "KEYTRUDA": 1.7367786444185431, "LEVETIRACETAM": 8.421576799876128, "MEKINIST": 3.8748247051520415}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7922.json
index ccb2903299e..13fdebba82a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7922.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7922.json
@@ -1 +1 @@
-{"ABATACEPT": 6.677206798693604, "ACLIDINIUM": 1.6990409899318126, "ADALIMUMAB": 12.65047627171225, "APREMILAST": 2.329742859258386, "ARAVA": 50.23340268059884, "AZATHIOPRINE": 2.3637118211156816, "BELIMUMAB": 12.792718898788204, "BENLYSTA": 50.11757263885596, "CELLCEPT": 1.1345834263742522, "CIMZIA": 3.454064013744959, "ENBREL": 1.3058192791859535, "GARDASIL": 1.8158606101894503, "HIZENTRA": 1.252752730133875, "HUMIRA": 2.3803388454852783, "HYDROCHLOROTHIAZIDE": 4.660739266470458, "LEFLUNOMIDE": 1.32574957694799, "LUPKYNIS": 24.51061087989994, "NPLATE": 1.0580604351792484, "REMICADE": 1.0205867949604066, "SIMPONI": 1.5627053321349664, "XELJANZ": 1.1731589549003665}
\ No newline at end of file
+{"ARIPIPRAZOLE": 4.042557231707174, "BOTULINUM": 20.187719568132533, "BRIVARACETAM": 80.28682712562556, "COMIRNATY": 0.1043091018000554, "GARDASIL": 2.0193118932054994, "KEPPRA": 39.7725262109048, "LACOSAMIDE": 35.509268693550474, "LEVETIRACETAM": 62.927670597876926, "LEVOFLOXACIN": 2.6894062359271564, "OLANZAPINE": 3.885844457550731, "VIMPAT": 17.582460393016248, "null": 1.5003405974877269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7923.json
index 7c3c5108098..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7923.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7923.json
@@ -1 +1 @@
-{"ABATACEPT": 8.6466802816011, "ARAVA": 47.50591294671756, "BENLYSTA": 19.345375212279126, "STELARA": 3.639116816563101}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7924.json
index 56471aec215..472b88baccf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7924.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7924.json
@@ -1 +1 @@
-{"ASPARAGINASE": 18.281829632326176, "BASILIXIMAB": 73.45076368504093, "BUDESONIDE": 36.30205167735398, "CANCIDAS": 88.36836651328377, "CARMUSTINE": 76.24867406233687, "CASPOFUNGIN": 97.9650393519305, "CICLOSPORIN": 10.44367546239378, "CYTARABINE": 11.018346918548264, "DEXAMETHASONE": 6.428180304624633, "GANCICLOVIR": 27.389445312530945, "NOXAFIL": 60.837678206015845, "POSACONAZOLE": 157.89058464323432, "VENETOCLAX": 124.90642388616382}
\ No newline at end of file
+{"ABILIFY": 1.2560411352771348, "APIXABAN": 0.6628657409837885, "ARIPIPRAZOLE": 2.7711960061955074, "BOTULINUM": 2.5271794036805773, "BRINTELLIX": 0.8231461862888901, "BRIVARACETAM": 12.946037358036394, "BRIVIACT": 3.048821133390644, "BUPIVACAINE": 7.249311801855821, "BUPRENORPHINE": 0.7187976669063705, "CANCIDAS": 6.859555454295205, "CELECOXIB": 2.6012558103548904, "CELLCEPT": 1.240840372208189, "CICLOSPORIN": 0.6062415993226038, "COMIRNATY": 0.2442818496628225, "CYMBALTA": 2.079799582006377, "DEXAMETHASONE": 3.25897426105752, "DEXDOR": 34.91096421203645, "DEXMEDETOMIDINE": 11.69048483037068, "DULOXETINE": 5.929303810763567, "EBIXA": 10.89927844007874, "FENTANYL": 7.607919607974352, "GARDASIL": 1.5365222176957591, "GRANISETRON": 73.56009032098757, "HIZENTRA": 1.0382806253707828, "IBUPROFEN": 1.8250845066021764, "INFANRIX": 2.5149029554247417, "KEPPRA": 5.135472094020082, "KEYTRUDA": 0.2162065264988302, "LACOSAMIDE": 6.623771508870318, "LEVETIRACETAM": 10.287496522898865, "LEVODOPA": 10.331335123572996, "LEVOFLOXACIN": 1.7901308891817955, "LOXAPINE": 32.00133395568836, "LYRICA": 6.47233727556663, "MEMANTINE": 13.408167635860384, "MIDAZOLAM": 7.980450153190722, "MMRVAXPRO": 1.7275078395256072, "NIMENRIX": 1.2529795027522237, "OLANZAPINE": 3.424065871775253, "PEGINTRON": 0.2875566497995134, "PLAVIX": 0.3128622207815437, "PREGABALIN": 6.5220207312007, "REPAGLINIDE": 12.87899500681118, "RISPERIDONE": 10.635696612364184, "SODIUM": 24.15322610955697, "SPIKEVAX": 0.1379158494569125, "SUFENTANIL": 5.079150875332176, "TAMIFLU": 1.4149486140435672, "TOZINAMERAN": 0.2603785155488588, "VAXZEVRIA": 0.1176570368588268, "VIMPAT": 6.765741841462612, "ZYPADHERA": 1.6677470857022472, "ZYPREXA": 2.511097029462208, "null": 3.4509200496069847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7925.json
index 3e4f54501be..55e04a389ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7925.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7925.json
@@ -1 +1 @@
-{"ADCIRCA": 81.24768652958652, "CELLCEPT": 10.574153652848608, "DOCETAXEL": 38.2202431150985, "OPSUMIT": 15.174113401869349, "TRACLEER": 35.71621698934188}
\ No newline at end of file
+{"ABILIFY": 47.27087011475746, "COMIRNATY": 0.8606957413099764, "ENBREL": 25.052321193395933, "GARDASIL": 6.330061632747766, "VAXZEVRIA": 0.743165464068328, "ZOSTAVAX": 8.38078359054951, "null": 0.4488921735867295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7926.json
index f4ee7b730a4..0beb4e1b969 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7926.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7926.json
@@ -1 +1 @@
-{"null": 1.344765016654894}
\ No newline at end of file
+{"GARDASIL": 25.647032322582945, "null": 2.733501143242938}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7927.json
index 17ce177656c..b347e672fef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7927.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7927.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 44.36758355966221, "AVANDIA": 4.647644783279799, "CLOPIDOGREL": 6.265087614804869, "ENTRESTO": 11.076860304589946, "IBUPROFEN": 31.149638060258376, "OLANZAPINE": 4.341338407462684}
\ No newline at end of file
+{"CHOLESTAGEL": 993.1636323993032, "CICLOSPORIN": 2.5526297727730487, "COMIRNATY": 0.0607620782333712, "CUBICIN": 14.917097126754866, "NORVIR": 19.64221659720473, "OLANZAPINE": 2.229508862604197, "RIVAROXABAN": 40.47431124147492, "ZYPREXA": 4.32845365190316, "null": 2.598329686014328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7928.json
index 6fa03e8eb70..661875371dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7928.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7928.json
@@ -1 +1 @@
-{"CYMBALTA": 3.3053713182837003, "KEPPRA": 4.126278649887807, "null": 2.8035285066803484}
\ No newline at end of file
+{"null": 2.3148665892955407}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7929.json
index dd39df8b818..b938941cfd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7929.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7929.json
@@ -1 +1 @@
-{"ANAKINRA": 28.901442041962586, "CICLOSPORIN": 15.05023861167756, "KYMRIAH": 33.08506731837743, "STELARA": 11.782439767724885}
\ No newline at end of file
+{"FENTANYL": 23.208374721756822, "null": 2.973936754233856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/793.json
index 8fb986544f4..36a2f34e9c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/793.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/793.json
@@ -1 +1 @@
-{"COMIRNATY": 2.57867857852947}
\ No newline at end of file
+{"null": 4.799161565403609}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7930.json
index 11479be802c..126f3c8c649 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7930.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7930.json
@@ -1 +1 @@
-{"ASPARAGINASE": 96.109955574952, "CYTARABINE": 53.02214639499286}
\ No newline at end of file
+{"null": 4.067168470849009}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7931.json
index 8d718023d1b..8911948180a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7931.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7931.json
@@ -1 +1 @@
-{"ATRIPLA": 5.657631964314568, "BUSULFAN": 34.37570549720736, "LEMTRADA": 50.23150163508888}
\ No newline at end of file
+{"CICLOSPORIN": 9.296266762586718, "OLANZAPINE": 8.890888949167591, "null": 4.551727769802322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7932.json
index b602245360e..cd30c848633 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7932.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7932.json
@@ -1 +1 @@
-{"APIXABAN": 67.99347607957432, "CHAMPIX": 1.524086921154436, "ELIQUIS": 2.4097213627170437, "HUMIRA": 7.293448300319148, "RASILEZ": 10.017809356779676, "null": 1.3700022029744598}
\ No newline at end of file
+{"COMIRNATY": 7.470574449311385, "SPIKEVAX": 1.10976109311743, "VAXZEVRIA": 0.3265169440599466, "null": 0.296936706357601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7933.json
index ca9cba31ea9..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7933.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7933.json
@@ -1 +1 @@
-{"ACLIDINIUM": 1.555134709944083, "AERIUS": 2.6469209713109727, "AGOMELATINE": 5.768584291247288, "ARIPIPRAZOLE": 1.1311669999873084, "ATOSIBAN": 1.1194899450580733, "BENZODIAZEPINE": 1.1015466399223353, "BETADORM": 18.1461546350233, "BETMIGA": 4.85338060999789, "BEXSERO": 1.5739503236701473, "BOSENTAN": 1.111393142713856, "BRIDION": 3.1040630753613803, "BRINTELLIX": 1.2061315003381248, "BUPIVACAINE": 1.081584807774819, "CAELYX": 1.4069396960064755, "CIRCADIN": 1.1720346630844685, "COMIRNATY": 2.1664008122180958, "COMPRESSION": 10.315609476810822, "DESLORATADINE": 2.090378938673532, "DEXMEDETOMIDINE": 2.8067732548361444, "DUORESP": 1.3151692520234437, "ELASOMERAN": 1.305196998146198, "EMEND": 1.014754186382855, "ENOXAPARIN": 1.1514664385737683, "FASTURTEC": 1.7490608315796987, "FENTANYL": 2.3938711204929803, "FLEBOGAMMA": 7.8386890388498625, "FORSTEO": 1.9252411402902223, "GAZYVARO": 1.2180921952961918, "HERCEPTIN": 1.035945449807842, "HUMAN": 1.2738977056648737, "IBUPROFEN": 1.3333548756164797, "INVEGA": 1.8497772341406065, "IVABRADINE": 1.1982606713886592, "JCOVDEN": 3.4345710184958547, "KIOVIG": 4.515838472941581, "KYMRIAH": 2.503902500181681, "LEMTRADA": 1.433262339308655, "LOXAPINE": 1.5301336826033167, "MABCAMPATH": 1.194680880677779, "MELATONIN": 1.71140895390244, "MIDAZOLAM": 3.3846395221081487, "MIRABEGRON": 4.262459170990752, "MOVYMIA": 3.3846088669653067, "NAGLAZYME": 2.394002931237657, "NALOXONE": 1.9232608776301272, "NEVIRAPINE": 1.319922407659342, "OLANZAPINE": 2.515647125976313, "ONBREZ": 4.158076160277644, "ONCASPAR": 2.2196344759705298, "PALIPERIDONE": 1.8482557728726372, "PERJETA": 2.4274643492201573, "POPPERS": 2.351792581033437, "PRIVIGEN": 4.281118009858298, "QARZIBA": 4.493348216861191, "RAPISCAN": 1.4547507141353349, "RELVAR": 2.456254395304755, "REVINTY": 5.822310533764407, "RIXATHON": 1.094954811963994, "SITAGLIPTIN": 1.6534598841643189, "SPIKEVAX": 1.5702195273075528, "SUFENTANIL": 6.672075120743633, "SUGAMMADEX": 4.160834080250067, "TERIPARATIDE": 1.0240525379811214, "TERROSA": 1.101418598655724, "TIKOSYN": 1.9632659665328256, "TOZINAMERAN": 1.4093796984662397, "TRACTOCILE": 2.490921032690599, "TRICYCLIC": 12.793091217161722, "ULTIBRO": 2.7656072009510044, "VALDOXAN": 2.6008157514615013, "VAXZEVRIA": 1.558800110373122, "XYREM": 1.2383249990120964, "YESCARTA": 2.2369791658611637, "ZALASTA": 7.297925207129911, "ZARZIO": 1.3652679113582098, "ZIAGEN": 2.931969871553068, "ZYPADHERA": 4.088564252873231, "ZYPREXA": 1.5589528990969794, "null": 1.2360112813395572}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7934.json
index 51cfcbb4864..b28cc5c4981 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7934.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7934.json
@@ -1 +1 @@
-{"FENTANYL": 11.79496559070308, "null": 3.427714936082394}
\ No newline at end of file
+{"null": 1.0697945780850726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7935.json
index 4b41f3571b9..6b0faf9bdfc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7935.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7935.json
@@ -1 +1 @@
-{"null": 3.5657892944655663}
\ No newline at end of file
+{"ABACAVIR": 0.9376837191368088, "APIXABAN": 1.3582041194471777, "ARAVA": 0.0944542260870474, "ASPARAGINASE": 3.482507513095783, "AZATHIOPRINE": 1.98734499437319, "BUDESONIDE": 1.076410497470592, "CELLCEPT": 1.7755473592628437, "CICLOSPORIN": 4.922438617580615, "CLOPIDOGREL": 0.6594199917768457, "COMBIVIR": 3.215027357134657, "COMIRNATY": 0.2147236671278085, "CUBICIN": 14.004946015509192, "DEXAMETHASONE": 2.4681098534365398, "GARDASIL": 0.5738818722101108, "HUMALOG": 0.5503321328708002, "IBUPROFEN": 1.0894360096386817, "INSULIN": 1.557576005323097, "IPILIMUMAB": 4.157478503697465, "ISENTRESS": 4.118394638502645, "KEYTRUDA": 1.6772593108824805, "LEVOFLOXACIN": 2.014599162157199, "METHOTREXATE": 0.9069619645411798, "MYCOPHENOLATE": 5.382053437002213, "NUCALA": 0.748246236551873, "OLANZAPINE": 0.5466395631539925, "OMALIZUMAB": 3.225093456426903, "PEGASYS": 0.2880642360385035, "PEMBROLIZUMAB": 2.699256162964448, "SPIKEVAX": 0.1184234273190002, "STELARA": 1.1120025341459936, "SUTENT": 0.3609917401552449, "TICAGRELOR": 4.604628449945429, "TOZINAMERAN": 0.1612747682226551, "VAXZEVRIA": 0.0733952209919569, "VFEND": 1.1610239680656314, "XOLAIR": 0.7089856969433619, "ZOSTAVAX": 0.6889044238947767, "ZYPREXA": 0.7200869895781424, "null": 3.3620449046054737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7936.json
index 04c57b22a62..a7477df27e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7936.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7936.json
@@ -1 +1 @@
-{"COMIRNATY": 1.8922843296816263, "null": 1.3121127990571797}
\ No newline at end of file
+{"CICLOSPORIN": 26.247899062260643, "null": 1.812427923406882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7937.json
index 87ba3ac3117..743f05bc766 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7937.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7937.json
@@ -1 +1 @@
-{"ABILIFY": 5.41640874309355, "BRINTELLIX": 18.05471574742947, "CHAMPIX": 6.760559695497684, "CYMBALTA": 8.360011212844997, "INFLIXIMAB": 35.54190639486685, "LATUDA": 31.770158734798905, "OLANZAPINE": 2.6401312264251247, "SUBOXONE": 7.393156670914466, "ZYPREXA": 2.5554383542128964, "null": 2.043534684895}
\ No newline at end of file
+{"COMIRNATY": 5.2836422291525205, "KEYTRUDA": 0.6261174930773596, "MODERNA": 5.691354817371805, "SPIKEVAX": 4.95952318993707, "TOZINAMERAN": 5.760693736721654, "VAXZEVRIA": 0.2243976180557381, "null": 0.1881125958273387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7938.json
index f00738eefe0..5a5118baea6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7938.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7938.json
@@ -1 +1 @@
-{"MIDAZOLAM": 62.39276566404961, "null": 1.8886193394189712}
\ No newline at end of file
+{"CHAMPIX": 4.623903842525274, "COMIRNATY": 0.2212242841292281, "GARDASIL": 1.3048509511189734, "HUMALOG": 3.418048153878936, "LANTUS": 1.3528829714768094, "OZEMPIC": 84.59029363798813, "SPIKEVAX": 0.1438854286876013, "ZOSTAVAX": 4.930398934969993, "null": 4.269632536390682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7939.json
index fac1fec6500..287ef0bf374 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7939.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7939.json
@@ -1 +1 @@
-{"AFINITOR": 1.2097717914252428, "ALEMTUZUMAB": 1.3888411819540698, "ANAKINRA": 1.186384543258716, "ASPARAGINASE": 2.87409645787383, "ATOSIBAN": 15.340977595832918, "BEDAQUILINE": 2.693991802552421, "BUDESONIDE": 4.012604339831779, "CASPOFUNGIN": 2.365878417501478, "CELLCEPT": 1.2210841495770794, "CICLOSPORIN": 1.2839108374278798, "CLOPIDOGREL": 1.6293412328090204, "COMBIVIR": 1.162381952836408, "CUBICIN": 3.200896137197129, "CYTARABINE": 1.44039158844098, "DARZALEX": 7.098918515920892, "DEXAMETHASONE": 4.236357949203008, "DEXMEDETOMIDINE": 18.70953887988479, "EFAVIRENZ": 2.356036853822556, "ENOXAPARIN": 3.767979817967928, "ENTRESTO": 1.0330177950806163, "EUCREAS": 3.4290015117298958, "FENTANYL": 1.8974146973518136, "FILGRASTIM": 2.245706652746456, "FLEBOGAMMA": 20.042849176092307, "FUZEON": 34.84183565777153, "GANCICLOVIR": 3.407427283195473, "HERCEPTIN": 1.7259166765773075, "HUMAN": 3.6129081772202407, "HYDROCORTISONE": 2.38730204436444, "IRBESARTAN": 3.276830169181945, "JARDIANCE": 3.2400753905934185, "KALETRA": 1.747362419584796, "KIOVIG": 6.077481772494963, "KYMRIAH": 7.78723374135085, "LAMIVUDINE": 3.907032519026677, "LEVOFLOXACIN": 3.214377005780406, "METFORMIN": 2.9277723342477344, "MIDAZOLAM": 2.6249652405781188, "NAGLAZYME": 8.241698594404456, "OLANZAPINE": 3.702502457495119, "PRIVIGEN": 12.14327144564711, "RISPERIDONE": 4.637826717789036, "RIVAROXABAN": 5.382116393626405, "SPIRONOLACTONE": 2.356091645541289, "SYNAGIS": 5.782537664633024, "TAMIFLU": 1.757340807512353, "TICAGRELOR": 8.387425090653139, "ULTIBRO": 27.489483313897065, "VALSARTAN": 4.55760357703481, "YESCARTA": 3.25688135546752, "ZYPREXA": 1.0054900807660048, "null": 2.183055231535856}
\ No newline at end of file
+{"LATUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/794.json
index 6977e3bddd2..f3d9ac3b98a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/794.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/794.json
@@ -1 +1 @@
-{"CYTARABINE": 14.49784258602676, "null": 1.2499479751446287}
\ No newline at end of file
+{"null": 1.7303640841198316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7940.json
index 8cf1e3a4a57..9c90f27b81b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7940.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7940.json
@@ -1 +1 @@
-{"ADALIMUMAB": 7.962753158463122, "INFLIXIMAB": 135.00071655905907}
\ No newline at end of file
+{"COMIRNATY": 1.336643451578204, "OPTIMARK": 136.6886234996496, "SPIKEVAX": 0.7927862367294788, "VAXZEVRIA": 0.4240422805508975, "null": 0.644488547498857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7941.json
index 15a7ff00e89..a2ff48c7d2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7941.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7941.json
@@ -1 +1 @@
-{"COMBIVIR": 30.08190886333052, "ENOXAPARIN": 6.548371931157626, "IRON": 16.78504778320923, "KEPPRA": 4.36565914847678, "LEVETIRACETAM": 5.463303368911634, "OLANZAPINE": 2.440000705024947, "STELARA": 1.2084274113544429, "SUBOXONE": 3.210260962316968, "ZYPREXA": 5.520231839178042, "null": 7.1162154846721055}
\ No newline at end of file
+{"ADCETRIS": 32.32992431704492, "ALEMTUZUMAB": 1.79879873807942, "ALIMTA": 2.1465364922288632, "ARAVA": 0.2189682368135147, "AVANDIA": 0.5318160437973388, "AVELUMAB": 14.199936351905746, "AXITINIB": 9.9170114449366, "AZATHIOPRINE": 4.060492389985598, "BAVENCIO": 27.05833074633933, "BIKTARVY": 3.2123078701029257, "BRAFTOVI": 2.126588931767969, "BRILIQUE": 1.8931245945624693, "CABOMETYX": 1.5096560202633968, "CAPECITABINE": 2.6475425150614376, "CELLCEPT": 0.9055983911994872, "CHAMPIX": 0.529871199217962, "CICLOSPORIN": 1.4396179800984612, "COBIMETINIB": 14.818580655751855, "COMIRNATY": 0.8098462187257099, "CUBICIN": 10.66438994533109, "ELIQUIS": 0.4478844138457996, "FASLODEX": 1.6306489036531695, "GARDASIL": 1.455902958733266, "HUMAN": 3.272246203064949, "INLYTA": 1.247289863032048, "IPILIMUMAB": 23.00058399342101, "ISENTRESS": 8.922576589883747, "JAKAVI": 2.7500682781119186, "KEYTRUDA": 20.54627431368768, "LIBTAYO": 24.899890572959738, "MEKINIST": 1.924535847848185, "MODERNA": 0.8581771555740773, "NEXAVAR": 0.4720011873432609, "OPDIVO": 25.150991347116992, "PEGASYS": 1.672904993405118, "PEGINTRON": 1.1828425918078609, "PEMBROLIZUMAB": 17.1484350431254, "SHINGRIX": 0.7176437724941895, "SIMPONI": 0.8369712351365353, "SPIKEVAX": 0.6263868862720546, "STELARA": 1.187703020650088, "TAMIFLU": 1.9747228914021733, "TOZINAMERAN": 0.7885869511483516, "TWINRIX": 4.152910507792303, "VAXZEVRIA": 0.4238717452173366, "XELJANZ": 0.3569371402029736, "XOLAIR": 0.7841624517828082, "ZOSTAVAX": 1.2037620393992037, "null": 0.7827795601091925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7942.json
index 925984eb1a5..969aefd758b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7942.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7942.json
@@ -1 +1 @@
-{"null": 1.0379271266124754}
\ No newline at end of file
+{"null": 1.6898317712735529}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7943.json
index 6b2f75cffeb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7943.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7943.json
@@ -1 +1 @@
-{"ABILIFY": 26.24833478342308, "ARIPIPRAZOLE": 25.34287686097129, "BREXPIPRAZOLE": 86.4079128185948, "BRINTELLIX": 1.2994513323246424, "BUPRENORPHINE": 1.587725475796501, "CYMBALTA": 2.168629695426599, "DULOXETINE": 3.277296277384931, "INVEGA": 54.95648117928224, "LATUDA": 107.3720914635213, "LOXAPINE": 54.984589144793546, "LURASIDONE": 32.6024874450853, "MELATONIN": 5.1147555069746025, "OLANZAPINE": 35.111911796354974, "RISPERIDONE": 11.535893240526423, "ZYPADHERA": 5.6349484121202185, "ZYPREXA": 23.68293687485168, "null": 2.524078419549817}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7944.json
index f62aad00633..02682addf62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7944.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7944.json
@@ -1 +1 @@
-{"CELECOXIB": 529.9483074308141, "DEXAMETHASONE": 33.369830107623706}
\ No newline at end of file
+{"null": 1.1143824523374972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7945.json
index 84dfeefe190..8df5a413716 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7945.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7945.json
@@ -1 +1 @@
-{"ABASAGLAR": 1.1777927450331265, "ABRAXANE": 1.762504258849923, "ADALIMUMAB": 1.002889443864632, "AFINITOR": 2.7495831874741232, "AIMOVIG": 8.82955943938664, "ALIMTA": 1.0372589041216596, "ANORO": 1.692653983159694, "APREMILAST": 7.716361181389326, "AVAMYS": 2.9794160195307478, "AXITINIB": 1.6524389607665564, "BOCEPREVIR": 3.953089900554972, "BRAFTOVI": 1.320349552498972, "BRINTELLIX": 1.8082376378395368, "CABOMETYX": 15.592530148089512, "CHAMPIX": 2.820162667201814, "COAPROVEL": 1.0669596737516165, "DOCETAXEL": 1.1066508107068185, "ERLEADA": 1.877699424770346, "ESBRIET": 2.501379468890061, "FASLODEX": 1.8113315377091488, "HALAVEN": 1.333777124490679, "HERCEPTIN": 1.3229483516821894, "IBRANCE": 2.473688549528689, "INCIVO": 1.058767952100019, "INLYTA": 2.7504690893114296, "IRESSA": 1.72707156489753, "JEVTANA": 2.8075736469532875, "KEYTRUDA": 1.522428793871614, "KISQALI": 1.5765887708517177, "LENVIMA": 1.418304177892722, "LONSURF": 2.652450755374248, "LYNPARZA": 6.621062715260355, "NINLARO": 1.378009818410408, "OFEV": 2.0028583095256924, "OPDIVO": 1.0892933482491185, "PAZOPANIB": 2.1667296057952354, "PEGASYS": 2.2379391352285785, "PEGINTRON": 1.8961140294294971, "RELVAR": 2.425311472002749, "REVLIMID": 1.1064567395506664, "RUBRACA": 5.807960413659807, "RYBELSUS": 3.243680067086532, "SAXENDA": 1.3882153203423788, "SUTENT": 13.197897258188377, "TAGRISSO": 3.310603632309159, "TRULICITY": 1.3941206618087698, "VOTRIENT": 5.687004959638173, "XALKORI": 6.141023578679089, "XTANDI": 3.697972778776074, "ZEJULA": 4.73597570467942, "ZELBORAF": 2.7497857124415304, "null": 1.0745131009132345}
\ No newline at end of file
+{"null": 0.4689249906284953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7946.json
index 97fa1a826f2..09625d32d70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7946.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7946.json
@@ -1 +1 @@
-{"null": 2.8888362465479496}
\ No newline at end of file
+{"null": 1.5345798162876387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7947.json
index 2ee284beca4..105359b60f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7947.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7947.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 2.079278683547065, "ATAZANAVIR": 274.57716594713185, "BEXSERO": 12.311305309757472, "BRINTELLIX": 2.658795535421364, "CHAMPIX": 42.72366678673967, "CYMBALTA": 1.940030400815263, "ENFUVIRTIDE": 126.96567792080737, "GARDASIL": 1.2310204471073405, "INSULIN": 2.421532172463406, "MMRVAXPRO": 2.955086151459067, "NIMENRIX": 5.2838289523440585, "ROTATEQ": 4.29196254850502, "null": 1.201075697419278}
\ No newline at end of file
+{"COMIRNATY": 0.2665903694243147, "SUTENT": 8.682133886623497, "null": 1.0185083493070606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7948.json
index 24ebfd349ea..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7948.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7948.json
@@ -1 +1 @@
-{"ATRIPLA": 36.19989430414055, "STRIBILD": 23.07609301873647, "TRUVADA": 13.802859350777782}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7949.json
index 3d9fdf2deee..cdbe4abff4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7949.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7949.json
@@ -1 +1 @@
-{"COVID19": 1.9563649083217247}
\ No newline at end of file
+{"IRBESARTAN": 400.94499438346753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/795.json
index c04897d31db..dded7d31bb4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/795.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/795.json
@@ -1 +1 @@
-{"null": 4.27009467894008}
\ No newline at end of file
+{"ZYPREXA": 16.890541440676117, "null": 5.494009898438165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7950.json
index 27212746a55..ee21d5c8155 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7950.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7950.json
@@ -1 +1 @@
-{"COSENTYX": 6.60480688470877, "VAXZEVRIA": 1.2482241168708297, "null": 1.0830985071185784}
\ No newline at end of file
+{"APIXABAN": 5.2160940398356646, "CLOPIDOGREL": 14.222854993739892, "COMIRNATY": 0.740096120562475, "ELIQUIS": 3.220012211747965, "ENALAPRIL": 148.79490798639085, "ENTRESTO": 100.90825695767376, "IVABRADINE": 80.44381262534556, "JARDIANCE": 2.4419678053457843, "KEYTRUDA": 1.879585693486612, "OPSUMIT": 7.346892627878121, "SPIKEVAX": 0.2929539287086607, "TRACLEER": 5.34967562309036, "VALSARTAN": 70.02456107608491, "null": 0.5091140662329116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7951.json
index b39134c243e..8679cb18d1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7951.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7951.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.971942231748961, "TOZINAMERAN": 3.6979745886150166}
\ No newline at end of file
+{"ENTRESTO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7952.json
index 6901e46e73f..1bc872927b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7952.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7952.json
@@ -1 +1 @@
-{"ABILIFY": 1.3317454646767035, "AIMOVIG": 1.3364410557967004, "AUBAGIO": 4.28999643454293, "BEVACIZUMAB": 2.58504977342049, "CARBIDOPA": 11.711141254296294, "DARZALEX": 20.89466903349048, "DEXAMETHASONE": 1.2811048572501047, "DOCETAXEL": 1.9315182900061536, "FAMPYRA": 12.010170508311834, "GALAFOLD": 21.084889731617096, "GARDASIL": 2.534298848519278, "HERCEPTIN": 5.6878798243618585, "IRINOTECAN": 4.284914392819486, "LATUDA": 2.642258719239546, "LEMTRADA": 14.926050538212602, "LEVOFLOXACIN": 3.85459657672525, "OMALIZUMAB": 2.9747576488066234, "PEGASYS": 1.6356846606575477, "PROPRANOLOL": 8.750522323980825, "STIVARGA": 2.4642145382163694, "SUTENT": 2.4802620551109054, "TOZINAMERAN": 1.3536927268258194, "XOLAIR": 2.987774435861719, "XTANDI": 1.3504483319501286, "ZOSTAVAX": 1.017308983886049, "null": 1.387804786345941}
\ No newline at end of file
+{"FIRDAPSE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7953.json
index 18755cd4c60..bd19cb79c5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7953.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7953.json
@@ -1 +1 @@
-{"COMIRNATY": 3.092420740037095}
\ No newline at end of file
+{"AVAMYS": 2576.516322770065}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7954.json
index 3813c5dda6f..c8efbab1284 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7954.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7954.json
@@ -1 +1 @@
-{"ABACAVIR": 188.0771604736076, "COMIRNATY": 1.897542790240517, "COVID19": 1.0171803987761543, "ENBREL": 4.137258353255031, "GARDASIL": 3.3714104182582108, "HARVONI": 3.95601656254784, "HUMIRA": 4.074407710586363, "HYDROCORTISONE": 12.169902675443296, "ORENCIA": 53.63763133864882, "SHINGRIX": 1.124523450808656, "VAXZEVRIA": 1.3144060564754223}
\ No newline at end of file
+{"STIVARGA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7955.json
index 21536711425..5e6e8c518c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7955.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7955.json
@@ -1 +1 @@
-{"ASPARAGINASE": 137.07824227255696, "KEPPRA": 8.620988439107695, "LEVETIRACETAM": 15.916514601487258, "null": 1.5247854650299362}
\ No newline at end of file
+{"PANITUMUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7956.json
index dd73b36d5f6..97026e1c554 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7956.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7956.json
@@ -1 +1 @@
-{"ATRIPLA": 1.0449701837036005, "COSENTYX": 5.05561558739295, "TOZINAMERAN": 1.3363942116820509, "ZOSTAVAX": 10.11146093499598}
\ No newline at end of file
+{"null": 1.6394521558220654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7957.json
index e40eb214ed0..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7957.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7957.json
@@ -1 +1 @@
-{"COSENTYX": 190.28093922693932}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7958.json
index 1cf39224876..8669278819f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7958.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7958.json
@@ -1 +1 @@
-{"ENBREL": 664.4925987928443}
\ No newline at end of file
+{"SPIRONOLACTONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7959.json
index a414be09540..b45b3124677 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7959.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7959.json
@@ -1 +1 @@
-{"AFINITOR": 1.2102969050395798, "ARIPIPRAZOLE": 3.8349396066396895, "COMIRNATY": 1.7651792525846113, "COSENTYX": 3.2346361041891734, "COVID19": 4.954230555865419, "ENBREL": 1.542497594174275, "ENOXAPARIN": 2.291590807787024, "EVEROLIMUS": 2.49096443730201, "GARDASIL": 1.07017768781777, "LEFLUNOMIDE": 1.904999660598913, "MENVEO": 1.9169627933702755, "METHOTREXATE": 11.126105987470062, "PANTOPRAZOLE": 1.8290898625737024, "SHINGRIX": 2.323960855289271, "SPIKEVAX": 2.4151363067476264, "TOZINAMERAN": 1.5027790918832913, "VAXZEVRIA": 2.279778543409945, "XELJANZ": 1.0211942217656902}
\ No newline at end of file
+{"ABRAXANE": 1241.19955539701, "null": 0.2954297519074482}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/796.json
index cc0eb74eed2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/796.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/796.json
@@ -1 +1 @@
-{"ARANESP": 4.719695428709936, "AVANDIA": 1.8318437260651808, "CELLCEPT": 3.2794539122333117, "CICLOSPORIN": 6.221864151678105, "ENTRESTO": 3.160396016433929, "EXJADE": 3.514590358387216, "FORSTEO": 1.9858586624500485, "LEVOFLOXACIN": 2.0010674817089877, "PEGINTRON": 2.006257349114239, "SOLIRIS": 2.5321653911045474, "SUTENT": 1.6231542701868134, "VIREAD": 6.17060581069334, "VOTRIENT": 2.1059066794008943, "null": 1.9836275485328287}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7960.json
index f0f469499ca..9a2d3eec3af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7960.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7960.json
@@ -1 +1 @@
-{"null": 1.4912809900639403}
\ No newline at end of file
+{"COMIRNATY": 0.4098180319027069, "SUTENT": 4.8568457309882, "VAXZEVRIA": 0.6320144208567909, "null": 0.4149313245380323}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7961.json
index c2db7e48224..3113e3f0bdf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7961.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7961.json
@@ -1 +1 @@
-{"LEVOFLOXACIN": 32.8117707554745, "null": 3.68882999456238}
\ No newline at end of file
+{"null": 0.4588045923273245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7962.json
index 400e6454e0d..17a3ff926ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7962.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7962.json
@@ -1 +1 @@
-{"ABILIFY": 1.955636955013821, "APIDRA": 2.7638024226646825, "ARAVA": 1.427430433098274, "COSENTYX": 3.1349674617273133, "ENBREL": 1.0364709960860967, "FESOTERODINE": 61.27244894001729, "LEFLUNOMIDE": 10.059628227026568, "LEVOFLOXACIN": 27.97803066450283, "OPTIMARK": 3.5843842753130137, "XELJANZ": 1.7517856580357225, "null": 3.0010830691566244}
\ No newline at end of file
+{"null": 0.5983845148152901}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7963.json
index 34f8943f22a..50c396a06d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7963.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7963.json
@@ -1 +1 @@
-{"COSENTYX": 1.7419004048486926, "LEVOFLOXACIN": 20.835173229723043, "SIMPONI": 1.602814845246498, "XELJANZ": 1.014835604049597, "null": 7.488684495059885}
\ No newline at end of file
+{"TAGRISSO": 116.04007033133642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7964.json
index ea2b528ccc3..6441cdba4a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7964.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7964.json
@@ -1 +1 @@
-{"CIMZIA": 3.0778554884587708, "LEVOFLOXACIN": 50.72076838887962, "null": 3.381198426861797}
\ No newline at end of file
+{"null": 1.1019865723342448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7965.json
index 0623c5b5c23..16f229b36db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7965.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7965.json
@@ -1 +1 @@
-{"ARIXTRA": 7.886298648816006, "COLLAGENASE": 179.28475633377508, "CORTICOSTEROID": 43.66720773922663, "CORTICOSTEROIDS": 38.47378654180518, "HUMIRA": 1.7409197615274632, "LEVOFLOXACIN": 40.73205725739816, "SIMPONI": 1.6387904894193734, "XELJANZ": 1.5712392052550128, "XIAPEX": 100.7051940880498, "null": 6.527613565727274}
\ No newline at end of file
+{"ABACAVIR": 3.662884932648735, "COMBIVIR": 8.117974909087486, "COMIRNATY": 0.3835307571904091, "FORSTEO": 2.4712843628663403, "IBRANCE": 3.3054509364241857, "PEGASYS": 1.3697730194118816, "SPIKEVAX": 0.1428499632338444, "SUTENT": 5.7939876034657, "TOZINAMERAN": 0.7158499798305744, "VAXZEVRIA": 0.4785706429788892, "null": 0.9765276883734644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7966.json
index 936e8ef67d2..9ac2e216d7a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7966.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7966.json
@@ -1 +1 @@
-{"COMIRNATY": 2.579137776981064}
\ No newline at end of file
+{"null": 0.925299144556582}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7967.json
index c82dbd9ba5f..645730b31fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7967.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7967.json
@@ -1 +1 @@
-{"AMGEVITA": 103.15099803175072, "COSENTYX": 2.472584472184263, "CYMBALTA": 2.7339527060204096, "DULOXETINE": 1.1560952289392017, "EMPAGLIFLOZIN": 3.5214035165709885, "HUMIRA": 1.0340282807538517, "HYDROCORTISONE": 4.708546931594012, "LEFLUNOMIDE": 3.6809391631386026, "LEVOFLOXACIN": 45.89371335963192, "MICARDIS": 2.7738688039730124, "SOMAVERT": 21.905398881491408, "XOLAIR": 1.0835223494622606, "null": 3.0915212672759}
\ No newline at end of file
+{"ABATACEPT": 32.031197120741275, "ADALIMUMAB": 2.0286829127982475, "AFINITOR": 5.515041807431839, "AIMOVIG": 1.569543319230532, "ARAVA": 2.6396429012077487, "AUBAGIO": 3.7817390360638634, "CAPECITABINE": 5.097131123146316, "CIMZIA": 7.333464786126508, "COMIRNATY": 0.1205941437879336, "COSENTYX": 3.40243070959928, "DOCETAXEL": 14.730235569039053, "FORSTEO": 1.218574598804142, "HERCEPTIN": 11.556539537691254, "IBRANCE": 8.246128167034152, "IRESSA": 11.708200467416654, "KEPPRA": 1.9337549308130744, "KEYTRUDA": 0.7889511705914736, "PEGASYS": 1.5151250016338718, "PEGINTRON": 0.9260405998281288, "SPIKEVAX": 0.0986634037577772, "SUTENT": 2.415296057715313, "TAGRISSO": 27.50616212964865, "TORISEL": 17.982508451786252, "TOZINAMERAN": 0.1927677257299315, "XELJANZ": 1.1223626915620109, "XTANDI": 1.25109331914848, "null": 0.6310202774766427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7968.json
index 1482483133d..d0d80390154 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7968.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7968.json
@@ -1 +1 @@
-{"null": 1.4863998810893884}
\ No newline at end of file
+{"CICLOSPORIN": 7.865918156123739, "null": 0.7780111825765705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7969.json
index 198d6136932..50277f1f9a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7969.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7969.json
@@ -1 +1 @@
-{"ABATACEPT": 2.9935436534030835, "ADALIMUMAB": 4.048562447724527, "ARAVA": 7.702459631349291, "AZATHIOPRINE": 11.59638775536134, "CIMZIA": 1.6629186889963532, "COSENTYX": 14.289532217459625, "ENBREL": 3.6383467405605687, "ESOMEPRAZOLE": 9.150863003963302, "HUMIRA": 3.207516355186352, "KEYTRUDA": 1.123052138195526, "LEFLUNOMIDE": 24.51529460698796, "LEVOFLOXACIN": 4.4358294418715785, "ROACTEMRA": 3.61970430627072, "SIMPONI": 1.6760183412707628}
\ No newline at end of file
+{"ARAVA": 1.858857531221988, "null": 0.8531043023033507}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/797.json
index 53ef0c1ba9d..416b984744d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/797.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/797.json
@@ -1 +1 @@
-{"BLINCYTO": 776.1144927464509, "CYTARABINE": 57.5122810435514, "KYMRIAH": 80.35453078541197}
\ No newline at end of file
+{"NEXAVAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7970.json
index 9a510de4d7a..019342fdabb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7970.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7970.json
@@ -1 +1 @@
-{"null": 1.1890343634009342}
\ No newline at end of file
+{"null": 0.4894537929896228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7971.json
index 293580ec362..1288bb18f6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7971.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7971.json
@@ -1 +1 @@
-{"ABILIFY": 2.224285691146488, "ARIPIPRAZOLE": 3.481964684966067, "AVANDIA": 1.2807736531195957, "BRINTELLIX": 10.457214105381734, "CHAMPIX": 2.9726039916013787, "CHORIOGONADOTROPIN": 213.8081397999383, "CYMBALTA": 1.1551951204324569, "FOLLITROPIN": 123.06189481328347, "GONALF": 46.24916265749008, "KEPPRA": 1.5929069727404994, "OLANZAPINE": 2.923917671602552, "PLAVIX": 3.7976619066512503, "SERTRALINE": 111.91417830769328, "ZYPREXA": 2.702980224401572, "null": 2.37480451898001}
\ No newline at end of file
+{"XELJANZ": 9.918432866722828, "null": 0.6566804085569199}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7972.json
index 8a76500d31e..ff90b4a0ccd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7972.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7972.json
@@ -1 +1 @@
-{"AIMOVIG": 5.216569843638351, "APIXABAN": 2.9013963773802973, "BRINTELLIX": 2.898969126518746, "COMIRNATY": 1.33012945815663, "COVID19": 8.27176381159892, "GARDASIL": 2.118309119424083, "SPIKEVAX": 1.2236397700603925, "TOZINAMERAN": 3.8627439195794806, "VAXZEVRIA": 1.9046981813481096}
\ No newline at end of file
+{"null": 0.5976441121986223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7973.json
index c5f78ffaef2..ffeba584d92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7973.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7973.json
@@ -1 +1 @@
-{"KEPPRA": 35.01663438497142, "LEVETIRACETAM": 34.61988502289864, "null": 1.892904534458536}
\ No newline at end of file
+{"ARAVA": 7.458798363398371, "CIMZIA": 20.74109551889321, "null": 0.4146612153111814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7974.json
index e34549b3575..98cf84a9778 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7974.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7974.json
@@ -1 +1 @@
-{"null": 1.4575876932770813}
\ No newline at end of file
+{"null": 0.8606339996356857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7975.json
index 8e786da29b7..751543a20d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7975.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7975.json
@@ -1 +1 @@
-{"null": 2.704189143603206}
\ No newline at end of file
+{"null": 0.4491125594149601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7976.json
index 8cdfbfa4fbd..43534b61e30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7976.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7976.json
@@ -1 +1 @@
-{"null": 6.404820898709732}
\ No newline at end of file
+{"CIMZIA": 12.584651601708872, "COMIRNATY": 0.5681542650220396, "COSENTYX": 44.24321048042794, "STELARA": 13.814106150886388, "TREMFYA": 93.221710785555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7977.json
index f74df163d90..13332de9731 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7977.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7977.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.152172183462422}
\ No newline at end of file
+{"COMIRNATY": 0.3544646564951268, "null": 0.7386262337317547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7978.json
index b98b0341386..c75ff0e80f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7978.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7978.json
@@ -1 +1 @@
-{"COSENTYX": 7.886366758001173, "TOZINAMERAN": 1.2552376149918345, "null": 1.4477828553496626}
\ No newline at end of file
+{"null": 2.319713095995556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7979.json
index 5017031eb8a..8f3075285de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7979.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7979.json
@@ -1 +1 @@
-{"AFINITOR": 2.592940712326932, "ANAKINRA": 76.00822313181803, "ARANESP": 12.19747309376526, "ENBREL": 2.54361559263112, "EXJADE": 8.640217524012392, "FAMPYRA": 6.328342557353514, "FASLODEX": 3.1303305151578966, "IBRANCE": 2.163928710991041, "JAKAVI": 3.481818508214796, "KEPPRA": 1.6239224171122724, "KEYTRUDA": 1.7399173292124843, "LONSURF": 8.481058799994022, "NEULASTA": 5.529934000448899, "OPSUMIT": 12.696149308023712, "REVATIO": 21.85705375953049, "SOLIRIS": 2.657530068205909, "STIVARGA": 3.174351485649747, "TRACLEER": 15.756491734455532, "TRELEGY": 5.339048304557634, "VOTRIENT": 5.308851107708662, "XTANDI": 13.890725342976491}
\ No newline at end of file
+{"CHAMPIX": 4.238925901352602, "COMIRNATY": 0.6860172521907992, "GARDASIL": 23.594900772762877, "MIRABEGRON": 111.92070764111224, "SPIKEVAX": 0.4187010949228499, "TOZINAMERAN": 1.1475382749440086, "VAXZEVRIA": 0.4062930558439199, "XYREM": 48.93970589237109, "ZONISAMIDE": 118.53825262590009, "null": 0.8884741949414138}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/798.json
index cb9c29b3d5a..d7528228bca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/798.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/798.json
@@ -1 +1 @@
-{"KYMRIAH": 3400.4029704541445, "YESCARTA": 105.01606126652784}
\ No newline at end of file
+{"null": 2.880590035536887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7980.json
index 94dcee7c3de..ea8618f1c46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7980.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7980.json
@@ -1 +1 @@
-{"JARDIANCE": 98.2258618932756}
\ No newline at end of file
+{"null": 0.8652203883472588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7981.json
index 89e0e4415ee..0c29b1dfc61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7981.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7981.json
@@ -1 +1 @@
-{"BUSULFAN": 56.37602115457624, "TESTOSTERONE": 131.1330952288465, "null": 4.189697507565455}
\ No newline at end of file
+{"null": 3.024396352504493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7982.json
index 7dee1fd5056..436994a0f02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7982.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7982.json
@@ -1 +1 @@
-{"null": 1.6962176648425369}
\ No newline at end of file
+{"null": 0.4309090647495694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7983.json
index 32b5373c69f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7983.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7983.json
@@ -1 +1 @@
-{"SUTENT": 2.0327858945438604, "VIAGRA": 66.94492655886829, "null": 2.312823035789437}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7984.json
index fe2400a72b8..5f0c8dd3e53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7984.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7984.json
@@ -1 +1 @@
-{"null": 17.602001417614215}
\ No newline at end of file
+{"null": 6.805207901504371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7985.json
index fdffa6dd24c..7ae1c99f27e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7985.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7985.json
@@ -1 +1 @@
-{"null": 1.7203581838430817}
\ No newline at end of file
+{"null": 1.6892141769044025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7986.json
index 5841975ec60..4f7cb8d6fae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7986.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7986.json
@@ -1 +1 @@
-{"null": 1.695933139054759}
\ No newline at end of file
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7987.json
index d616075c562..53dfd1bb1bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7987.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7987.json
@@ -1 +1 @@
-{"null": 1.1647388436024968}
\ No newline at end of file
+{"ABILIFY": 0.449350752056456, "ACLIDINIUM": 7.64959702258826, "ADCIRCA": 4.0079430509532, "ADEMPAS": 6.332022762905129, "ADENURIC": 6.065396477830619, "AERIUS": 1.307171514839501, "AFINITOR": 0.7855014796526949, "AIMOVIG": 0.9589079262353336, "ALDARA": 2.02742515866795, "ALEMTUZUMAB": 0.4957586611559902, "AMBRISENTAN": 8.602002550380435, "ANORO": 2.2811884820310686, "APROVEL": 1.0554335050414412, "ARAVA": 0.4322528559584769, "ASPARAGINASE": 0.5614775276602119, "AUBAGIO": 0.3787416727791092, "AVAMYS": 19.623993326252357, "AVASTIN": 0.361702928495629, "BENLYSTA": 1.8233752467407436, "BENRALIZUMAB": 5.670922704022179, "BEXSERO": 1.798611597243002, "BRINTELLIX": 0.2538484096394017, "BUDESONIDE": 6.789568429258964, "BUPRENORPHINE": 0.3084798657915707, "BYDUREON": 0.3995915488332468, "CHAMPIX": 0.5571642897003979, "CIALIS": 1.914194765068708, "CICLOSPORIN": 0.6340380783666402, "CIMZIA": 0.5828128353922067, "CLOPIDOGREL": 0.738788429093135, "COMIRNATY": 0.968672203368664, "COSENTYX": 1.7567082014635778, "CYMBALTA": 0.435562403943674, "CYTARABINE": 0.8053874555576103, "DARZALEX": 3.133281544677238, "DEXAMETHASONE": 0.486815239396893, "DUPIXENT": 3.884888540408189, "ELIQUIS": 0.1837114817886792, "ENBREL": 0.4195136093326824, "ENTRESTO": 0.3698304400789171, "ENTYVIO": 1.5301030846950725, "ESBRIET": 1.0859900008027832, "ESOMEPRAZOLE": 0.749061213466457, "EXFORGE": 1.1532181594728286, "EXJADE": 0.2395078602955708, "FASENRA": 3.551588319098203, "FLUCELVAX": 3.367103316474033, "FLUTICASONE": 10.01175277717234, "FORSTEO": 0.2229611630278921, "GALAFOLD": 2.8220767946630883, "GARDASIL": 0.9393356506315678, "HIZENTRA": 0.9194575128094246, "HUMALOG": 0.1011653652412068, "HUMIRA": 1.2482761771239566, "IBRANCE": 1.3741106432427994, "IBUPROFEN": 1.127121623737393, "INCRUSE": 1.5745764291037965, "INSULIN": 4.404901624536008, "JANUMET": 0.4827816959939459, "JANUVIA": 0.9949556266782424, "KAFTRIO": 2.0606345838110003, "KEPPRA": 0.1248454448071614, "KESIMPTA": 1.6555167398919814, "KEYTRUDA": 0.3669584846675984, "LANTUS": 0.1119383964943543, "LYRICA": 0.4288111819676432, "MACITENTAN": 4.338395642201544, "MEPOLIZUMAB": 7.567059375624751, "METHOTREXATE": 1.7635149821251708, "MMRVAXPRO": 0.5329595225316187, "MODERNA": 1.1682947741771883, "NAGLAZYME": 4.184875841004458, "NUCALA": 11.973440876208135, "OCRELIZUMAB": 0.5184780590269747, "OFEV": 1.1782201813864812, "OMALIZUMAB": 7.722894327642402, "OPSUMIT": 7.08142742433756, "ORKAMBI": 2.2737378618230006, "PANTOPRAZOLE": 0.9416659352470728, "PEGASYS": 0.6166616219270104, "PEGINTRON": 0.3976990223697029, "PLAVIX": 0.4300696397107338, "RELVAR": 2.179668623377172, "REVATIO": 2.088871531329061, "RITUXIMAB": 0.9284821848964494, "RIVAROXABAN": 3.487709706411384, "RIXATHON": 4.475975245137927, "ROACTEMRA": 0.3753250537103454, "ROTATEQ": 1.787343118785627, "SHINGRIX": 0.1977223928774598, "SILDENAFIL": 4.901126740203188, "SILODYX": 27.12149106958791, "SIMPONI": 0.2693951354918511, "SOLIRIS": 0.5770389683983427, "SPIKEVAX": 0.8661382902622777, "STELARA": 0.7180063569861812, "SUBOXONE": 0.2527465726546136, "SUTENT": 0.3819916008213839, "SYNAGIS": 8.841466414948421, "TAMIFLU": 1.164594685083714, "TASIGNA": 0.4053550791017689, "TOZINAMERAN": 2.1794576690897145, "TRACLEER": 1.5619933868859932, "TRELEGY": 1.77039193569653, "UROREC": 46.89901844546527, "VAXZEVRIA": 0.8004542750741258, "VIAGRA": 4.3726339451933, "VOTRIENT": 0.2706794346199478, "XELJANZ": 2.863758819826529, "XOLAIR": 4.818888881202088, "XTANDI": 0.4395500656033126, "ZOSTAVAX": 1.229300652406616, "ZYPREXA": 0.2130618022107482, "null": 0.9261889559080354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7988.json
index 5fcc5ae3652..07edf14bb3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7988.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7988.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 181.5807334887051}
\ No newline at end of file
+{"CEFUROXIME": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7989.json
index 8673b77d316..b8aab412313 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7989.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7989.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 2.894247738709812, "JARDIANCE": 1.6181131930278534, "KAFTRIO": 22.41079218541327, "PEGASYS": 1.0801670237470595, "SPIKEVAX": 1.3114383817232982, "TOZINAMERAN": 1.433756382989945, "UROREC": 47.36730823918848, "VIAGRA": 7.936793095010385, "XTANDI": 1.6560571672179072, "null": 2.120929254609536}
\ No newline at end of file
+{"AVAMYS": 27.479922880342755, "COMIRNATY": 0.5111369407685458, "COSENTYX": 24.59459875447231, "SPIKEVAX": 0.4704655432013737, "VAXZEVRIA": 0.6229246412656324, "null": 0.982205933655392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/799.json
index cb1b38db18b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/799.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/799.json
@@ -1 +1 @@
-{"ADVAGRAF": 71.8739148565652, "ASPARAGINASE": 8.670192031147167, "CELLCEPT": 9.695254238961295, "CICLOSPORIN": 25.711936006940807, "CIMZIA": 1.9241943411848488, "COSENTYX": 1.8870624744300784, "CYTARABINE": 3.7692094783503536, "DOXORUBICIN": 13.782308897792818, "ENTYVIO": 4.318384569045144, "JAKAVI": 4.580203866820011, "METHOTREXATE": 2.7643591427470477, "PEGINTRON": 2.109318584747225, "RITUXIMAB": 7.021131089419899, "SIMPONI": 3.271917969989118, "STELARA": 4.991420214786683, "XELJANZ": 1.3391720243273175, "YESCARTA": 25.700012548907285}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7990.json
index e0942f72557..27758240a93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7990.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7990.json
@@ -1 +1 @@
-{"null": 1.1422885138152594}
\ No newline at end of file
+{"null": 0.7618228783228234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7991.json
index 05a61b26d1a..cd57cca0d5f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7991.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7991.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 9.797689393279754, "PEGASYS": 3.4487037979944333, "SUTENT": 2.178794798929398, "TOZINAMERAN": 1.086325175039755, "VIAGRA": 25.60408404796653, "null": 1.0136887724738652}
\ No newline at end of file
+{"FORSTEO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7992.json
index 7d3d1269166..5f97310265c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7992.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7992.json
@@ -1 +1 @@
-{"null": 1.431887213883862}
\ No newline at end of file
+{"TRELEGY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7993.json
index e9d2715fc01..637d4b499b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7993.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7993.json
@@ -1 +1 @@
-{"SIMPONI": 2.285778282492445, "STELARA": 4.083491916500752, "SUBOXONE": 3.0007010654876933, "null": 8.981949558503054}
\ No newline at end of file
+{"AFINITOR": 17.184862063019043, "COMIRNATY": 0.1449419146978972, "MEPOLIZUMAB": 148.72347303717603, "OMALIZUMAB": 56.70101686564127, "null": 0.450082670445507}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7994.json
index b3d2aefa84d..21439f10d04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7994.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7994.json
@@ -1 +1 @@
-{"null": 1.8216547341603908}
\ No newline at end of file
+{"AVAMYS": 13.27574241814242, "BAQSIMI": 260.4657714333368, "CHAMPIX": 1.3340169990421, "CHLORHEXIDINE": 5.109512639514701, "COMIRNATY": 0.6553177859050147, "COSENTYX": 1.2983090833261293, "ENBREL": 2.6075402596629886, "ENTRESTO": 1.5278387198516437, "IBRANCE": 1.3594217801534547, "MEPOLIZUMAB": 1.7777365014775124, "RELVAR": 7.069956232398336, "SPIKEVAX": 0.5455584339956054, "SUTENT": 2.9588662733784177, "TOZINAMERAN": 1.215873952585218, "VAXZEVRIA": 0.7577660150146073, "XELJANZ": 0.676206577650884, "null": 2.2392361546262123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7995.json
index dc4829837d4..8b450ae460f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7995.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7995.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 4.409035809830213, "GARDASIL": 4.741035066336757, "MIMPARA": 45.6760341801204, "null": 2.038096788667631}
\ No newline at end of file
+{"COMIRNATY": 0.1029965413499445, "DOCETAXEL": 13.993811534848758, "IBRANCE": 2.09092391163993, "MEPOLIZUMAB": 5.78331089349596, "NUCALA": 15.867583288581526, "SUTENT": 4.63329954044934, "TOZINAMERAN": 0.6701242040311375, "null": 2.7572903656229752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7996.json
index 68bb712636f..3f6e7aa879e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7996.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7996.json
@@ -1 +1 @@
-{"null": 3.477477905696565}
\ No newline at end of file
+{"AFINITOR": 1.5358145624045598, "AVAMYS": 10.61490322809915, "CHAMPIX": 1.258885990754893, "CIMZIA": 1.0734857758094056, "COMIRNATY": 0.3898430407759398, "COSENTYX": 3.8263536859244343, "ELIQUIS": 1.0661202308743758, "IBRANCE": 2.674461582540237, "IBUPROFEN": 5.938367951767789, "JARDIANCE": 1.0070440905152287, "OPSUMIT": 2.3068278619616094, "PEGASYS": 0.826529871934517, "PEGINTRON": 1.1784144418203626, "SPIKEVAX": 0.3396131195100993, "SUTENT": 4.625293227926113, "TOVIAZ": 8.477493313926937, "TOZINAMERAN": 0.5116203115380548, "VAXZEVRIA": 0.5686724852431593, "XELJANZ": 0.8477613231103494, "null": 1.874829893815101}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7997.json
index fb62b76ee1f..8ccc7b2bc2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7997.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7997.json
@@ -1 +1 @@
-{"KEPPRA": 12.179153752324716, "SUBOXONE": 22.257280058813027, "null": 2.5071816331976864}
\ No newline at end of file
+{"null": 1.5365841720830886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7998.json
index 0a3bc1d94e1..a11fdbb5249 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7998.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7998.json
@@ -1 +1 @@
-{"COMIRNATY": 2.098663923536052, "ELIQUIS": 3.595917180351547, "VAXZEVRIA": 1.2814686165883655}
\ No newline at end of file
+{"COMIRNATY": 3.0023366543383303, "SPIKEVAX": 2.493744301010687, "VAXZEVRIA": 1.4194934435607929, "null": 0.0604739698956643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7999.json
index 10d96a81379..ea263476d49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7999.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/7999.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 9.871162068719578, "ELIQUIS": 53.66809023908258, "EVENITY": 16.490124475169907, "LIXIANA": 44.3668783129533, "PEGASYS": 1.4807259901308445, "PEGINTRON": 7.532296595928472, "PLAVIX": 11.22157820880138, "XARELTO": 12.366845981219775}
\ No newline at end of file
+{"COMIRNATY": 0.4122881128850854, "COSENTYX": 7.911044670360917, "SPIKEVAX": 0.4219818062014915, "VAXZEVRIA": 0.2916674595001193, "null": 1.1210493498306615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8.json
index 724046eb453..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8.json
@@ -1 +1 @@
-{"CYTARABINE": 15.57604961825209, "null": 1.5661041215056266}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/80.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/80.json
index 1b28e99bc3c..373d120d08a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/80.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/80.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 54.74420489178731, "IBUPROFEN": 14.791116197444202, "null": 3.902382049098631}
\ No newline at end of file
+{"ACTRAPID": 8.31855174511245, "ADALIMUMAB": 0.4745871849559172, "AFINITOR": 1.5957567648315147, "ALEMTUZUMAB": 1.861818522463944, "AMIKACIN": 7.868278144604589, "ANAKINRA": 3.369521401115291, "ARAVA": 0.1875982857740708, "AVASTIN": 2.7080778920550657, "BENLYSTA": 1.995833216614816, "BETAFERON": 10.47828900988403, "BEVACIZUMAB": 2.240269615809685, "BYETTA": 1.2961583599070174, "CELLCEPT": 1.8873530869060504, "CICLOSPORIN": 2.643891075001656, "CIMZIA": 5.650176867335564, "COMIRNATY": 0.2994165553347587, "COSENTYX": 2.524814693191307, "DEXAMETHASONE": 1.5458077166519388, "DOCETAXEL": 1.3932889260451626, "ELIQUIS": 0.4005130063838593, "ENBREL": 2.1441600950393678, "ENTYVIO": 9.924780317733337, "EXJADE": 1.793180811864839, "FASLODEX": 1.8299747405130635, "FORSTEO": 0.5967273846400258, "GARDASIL": 1.5578764427141298, "HIZENTRA": 2.525621428733284, "HUMALOG": 1.4712910656053562, "HUMIRA": 6.809282414915288, "IBRANCE": 0.5909926969278771, "INCIVO": 2.1076322238246754, "JARDIANCE": 2.694033193211934, "KEYTRUDA": 0.3451022192892721, "LANTUS": 1.4538501545152789, "LEVETIRACETAM": 1.6475988248857276, "LEVOFLOXACIN": 0.7618141935077264, "METHOTREXATE": 2.121080735885112, "MYCOPHENOLATE": 3.259838442479331, "PEGASYS": 2.8200358057637023, "PEGINTRON": 3.824662725041792, "PROPRANOLOL": 5.559588630152646, "REMICADE": 7.407814955138795, "RINVOQ": 2.215172342875747, "ROACTEMRA": 12.764668360260698, "SIMPONI": 6.347094702928869, "SOLIRIS": 1.4318938098194864, "SPIKEVAX": 0.2811891159760211, "STELARA": 4.911605103130762, "SUBOXONE": 0.7660418772431288, "SUTENT": 1.232533979453322, "TOZINAMERAN": 0.4340930343487547, "TREMFYA": 2.2445423577360937, "VAXZEVRIA": 0.220563668547647, "VOTRIENT": 0.8024749652723718, "XELJANZ": 1.0775027272445814, "ZOMETA": 13.327878876799396, "ZOSTAVAX": 1.315038241788613, "null": 0.9170802900360596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/800.json
index 9751001aa0d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/800.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/800.json
@@ -1 +1 @@
-{"CARMUSTINE": 235.7076294463422, "CYTARABINE": 56.52921272730367, "DEXAMETHASONE": 35.52400942881861, "DOXORUBICIN": 86.78978224602395, "MABTHERA": 87.60224945377034, "RITUXIMAB": 62.351405419933656}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8000.json
index a7dd66fbb8c..76ac8552cce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8000.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8000.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 71.05726999832552}
\ No newline at end of file
+{"SPIKEVAX": 0.3358950333534189, "SUTENT": 5.5639954846559565, "null": 1.7006335084140245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8001.json
index bd35408d732..b7a2ebdac24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8001.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8001.json
@@ -1 +1 @@
-{"HUMIRA": 200.9054819402286}
\ No newline at end of file
+{"null": 1.913393433494604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8002.json
index 4b649553f8a..18670d9d627 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8002.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8002.json
@@ -1 +1 @@
-{"SUBOXONE": 26.8826614579872, "null": 2.3324848978728823}
\ No newline at end of file
+{"AZILECT": 170.40505820682887, "COMIRNATY": 0.2225992189887166, "SPIKEVAX": 0.3686408831496784, "null": 2.382960850821602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8003.json
index dcaab357901..48198e5d56c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8003.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8003.json
@@ -1 +1 @@
-{"null": 2.9100638210069447}
\ No newline at end of file
+{"null": 0.9986656045005448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8004.json
index 8de7f374905..ad0cf314a5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8004.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8004.json
@@ -1 +1 @@
-{"null": 1.0228685254938332}
\ No newline at end of file
+{"null": 1.0779278232542049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8005.json
index 96133484cd8..cde221e5fea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8005.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8005.json
@@ -1 +1 @@
-{"null": 2.3007614168979083}
\ No newline at end of file
+{"null": 1.4408106887861092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8006.json
index c0e94141c55..06de585354a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8006.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8006.json
@@ -1 +1 @@
-{"ABATACEPT": 13.289828842623251, "ACTRAPID": 1.6132510063689818, "ADALIMUMAB": 5.862955601167547, "ADVATE": 2.1669892705539557, "AERIUS": 1.510756655336372, "AIMOVIG": 4.364717978775044, "ANAKINRA": 16.240962556610636, "APREMILAST": 10.591935002520287, "ARANESP": 1.3867951115850692, "ARAVA": 11.316951978945765, "AZATHIOPRINE": 10.12217932289879, "BARACLUDE": 1.3235500307445145, "BETMIGA": 1.125855778301093, "BLINCYTO": 4.227545948602611, "BRIDION": 1.315409316681966, "CERTOLIZUMAB": 9.091449399098853, "CHLORHEXIDINE": 40.964734001387, "CIALIS": 1.714630657059249, "CIMZIA": 19.04006000025908, "CINRYZE": 3.2720390997967184, "CORTICOSTEROIDS": 6.573842814511015, "COSENTYX": 4.677005106448232, "DAXAS": 13.85321575408534, "ENBREL": 18.353715178035905, "ENTYVIO": 1.9108601488736283, "ERELZI": 14.577250514364772, "ERENUMAB": 2.475058937947217, "ETANERCEPT": 4.728010150576854, "EYLEA": 1.0049900215455914, "FAMPYRA": 5.32948275007929, "FASENRA": 2.2401234419993195, "FIASP": 10.722730805040737, "FIRDAPSE": 1.9093550513454485, "FYCOMPA": 1.5503988295431963, "GLYCOPYRRONIUM": 1.9361027806287177, "GOLIMUMAB": 6.12036585884248, "HUMIRA": 12.583150218611037, "INVEGA": 2.461156267610725, "LACOSAMIDE": 1.3983096975589833, "LEFLUNOMIDE": 2.041337447852458, "MEPOLIZUMAB": 1.8004505192201294, "METHOTREXATE": 1.6734871744081987, "MIMPARA": 1.0914222161531657, "MIRCERA": 1.555728703464133, "NEULASTA": 1.0179681932103417, "NOVORAPID": 3.4513376420951225, "NPLATE": 6.578052971960744, "QUTENZA": 3.226998852160731, "REMICADE": 3.021511327266667, "RINVOQ": 4.722361518391275, "RITUXIMAB": 1.1795167038384695, "ROACTEMRA": 1.295995556504982, "SAXENDA": 1.5611628713407129, "SIFROL": 3.0787677808053973, "SILDENAFIL": 1.2893275685632588, "SIMPONI": 4.001942600489635, "SKYRIZI": 3.301838321950351, "SPINRAZA": 2.681196153624524, "STALEVO": 2.360618906236981, "STELARA": 5.185790142698638, "TESTOSTERONE": 2.223839866377145, "TOVIAZ": 1.8820052201154496, "TREMFYA": 2.918241430140565, "TRESIBA": 2.215786743725417, "UPADACITINIB": 4.62823904907316, "VIAGRA": 2.099528820459497, "XELJANZ": 1.4005943884722731}
\ No newline at end of file
+{"null": 1.4249640033172106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8007.json
index 45a709cb914..ed3683f5724 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8007.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8007.json
@@ -1 +1 @@
-{"AIMOVIG": 2.6244849548115163, "APIDRA": 6.61364248628943, "BRIDION": 17.859906269226983, "COMTAN": 17.956448450638707, "COSENTYX": 2.425279654508431, "ENTYVIO": 7.0914614835457135, "FIASP": 150.4986571043564, "HUMALOG": 6.786308042721581, "NOVORAPID": 27.396337164269465, "VIAGRA": 17.983703138134878, "XELJANZ": 12.894914124803362, "null": 1.903814934932719}
\ No newline at end of file
+{"AVAMYS": 135.54006726521615, "BUDESONIDE": 15.036371413982222, "COMIRNATY": 0.4730949841000405, "DARZALEX": 10.54799599864986, "MEPOLIZUMAB": 5.123196370833853, "NUCALA": 2.989867115279014, "SPIKEVAX": 0.1166194905518821, "VARENICLINE": 213.2398847970452, "VAXZEVRIA": 0.1255576495199802, "null": 1.2672116740756365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8008.json
index 21041fbd20f..4c5ffd12c5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8008.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8008.json
@@ -1 +1 @@
-{"ABILIFY": 6.062170272622497, "ACLIDINIUM": 11.954819182696554, "ADALIMUMAB": 3.4474201390167263, "AERIUS": 1.2135608931857589, "AIMOVIG": 2.9726681898622136, "ALENDRONATE": 18.54327645777149, "AMGEVITA": 16.622980979336923, "AMINOSALICYLIC": 12.73320183819205, "ANAKINRA": 10.216341338857733, "ANORO": 3.7859899798743952, "APIXABAN": 11.847295744364002, "ARAVA": 3.1106026350342577, "ARIPIPRAZOLE": 9.361426855363664, "AVAMYS": 28.0658591091407, "AZACITIDINE": 3.207622870808815, "AZATHIOPRINE": 5.233617026481319, "AZOPT": 17.83718082994475, "BENLYSTA": 1.314381847965204, "BENRALIZUMAB": 34.028339758869535, "BETMIGA": 2.971112277528776, "BEVACIZUMAB": 1.945261798956744, "BORTEZOMIB": 5.205485490624876, "BOTULINUM": 3.913267650956037, "BRIDION": 2.1194846167129024, "BRIVARACETAM": 2.8306722230930075, "BRIVIACT": 1.7939299816699483, "BUDESONIDE": 14.47211388881848, "C1": 6.700239562680315, "CAELYX": 1.256141410376275, "CAPECITABINE": 1.003313363340854, "CARBIDOPA": 1.309218695355142, "CARFILZOMIB": 3.1325303580485366, "CASPOFUNGIN": 1.6856442237138518, "CERTOLIZUMAB": 5.90620767203617, "CICLOSPORIN": 1.88685418322812, "CIMZIA": 1.9396150726747732, "CLADRIBINE": 3.4530407261775795, "COSENTYX": 5.332645697918995, "CYTARABINE": 1.9281897005650763, "DARZALEX": 1.292830920474492, "DASATINIB": 1.122664813428154, "DAXAS": 16.78249805602869, "DESLORATADINE": 8.12869851958033, "DEXAMETHASONE": 1.276981502931685, "DEXMEDETOMIDINE": 2.33233540626082, "DUAKLIR": 21.1836829678519, "DUORESP": 3.9154178181483377, "DUPIXENT": 3.41657850774348, "ENBREL": 6.292977619112028, "ENTYVIO": 2.1845932079856047, "ERELZI": 2.246784302922776, "ERENUMAB": 2.4787135928912334, "ERLEADA": 2.052843602200828, "ESOMEPRAZOLE": 2.499211104418301, "ETANERCEPT": 2.193100388495488, "EVENITY": 1.7628973301554205, "FASENRA": 1.0000500646049229, "FIRDAPSE": 5.672589215228185, "FLUTICASONE": 19.11538597280329, "FORMOTEROL": 81.60966613860693, "GLYCOPYRRONIUM": 33.59464907354145, "HIZENTRA": 1.0966924679549908, "HUMAN": 15.46923099115426, "HUMIRA": 5.335488103230087, "HYDROCORTISONE": 2.049848658028277, "IBRUTINIB": 5.515691145785869, "IBUPROFEN": 1.09054860981101, "IMATINIB": 1.002723822402651, "INCRUSE": 6.216511012375739, "INFLECTRA": 3.278875107376798, "INFLIXIMAB": 2.1393000337192074, "IRINOTECAN": 1.650428698343329, "IRON": 1.2237903050077878, "KYMRIAH": 4.7445036753695, "LACOSAMIDE": 6.7957209408945, "LEFLUNOMIDE": 2.7655217284640234, "LEVETIRACETAM": 3.3942691420320785, "LIRAGLUTIDE": 35.85473670224807, "LOPINAVIR": 3.5712745872998157, "LYRICA": 1.5268149716043298, "MELPHALAN": 1.1113271384734835, "MEPOLIZUMAB": 31.127464054027783, "METHOTREXATE": 3.0071358602391656, "MIDAZOLAM": 1.965635056288028, "MIMPARA": 2.550045975516255, "NPLATE": 1.1586260967463076, "NUCALA": 24.457094261444837, "OLANZAPINE": 1.2000525716874135, "OMALIZUMAB": 2.4279944772029403, "PANITUMUMAB": 2.1212230937447853, "PANTOPRAZOLE": 3.319942534893044, "PEMETREXED": 1.3903477745305144, "PREGABALIN": 6.304788063413934, "QUTENZA": 2.425639602122521, "RELVAR": 1.7717697100188137, "REMICADE": 2.195063013434256, "REVATIO": 1.0007669015553744, "REVOLADE": 5.53348925887042, "RINVOQ": 4.442196321109064, "RIOCIGUAT": 20.75869366568164, "RITUXIMAB": 1.0347782338834794, "RUCONEST": 12.941331693397478, "SILDENAFIL": 1.0113110195254549, "SKYRIZI": 2.7402657450757384, "STELARA": 1.3854759710261526, "TELMISARTAN": 5.949670181101318, "TEMOZOLOMIDE": 2.276155543131332, "TOVIAZ": 5.724249445277831, "TRELEGY": 2.86948186704888, "TREMFYA": 1.0236441829439404, "UMECLIDINIUM": 25.33617825864877, "UPADACITINIB": 2.655454623094807, "VARENICLINE": 7.740702146711989, "VECTIBIX": 1.293818032671153, "VENETOCLAX": 1.5813178095168243, "VIAGRA": 3.866545059249072, "VIGABATRIN": 2.921944205234387, "VORICONAZOLE": 1.7440342572725158, "XELJANZ": 10.417660906176646}
\ No newline at end of file
+{"null": 0.9316421351246048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8009.json
index 922714dfa88..aaf58cd6561 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8009.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8009.json
@@ -1 +1 @@
-{"FENTANYL": 3.1690337924431287, "HUMALOG": 2.337830126489203, "IBUPROFEN": 4.980268648153829, "LANTUS": 1.555307172391545, "null": 3.841837828361753}
\ No newline at end of file
+{"AVAMYS": 13.533616277838943, "COMIRNATY": 0.4169224887173574, "FLUTICASONE": 33.34341303341489, "NUCALA": 6.441097638172392, "OMALIZUMAB": 63.80063978344297, "SPIKEVAX": 0.2967980227929266, "SUTENT": 1.4372778838105509, "TASIGNA": 5.412061479712865, "TOZINAMERAN": 1.1774667414697064, "VAXZEVRIA": 0.4640352069037675, "ZOSTAVAX": 2.6095823897035904, "null": 1.3571285543076297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/801.json
index de58c485525..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/801.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/801.json
@@ -1 +1 @@
-{"CYTARABINE": 112.08803591853076}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8010.json
index 81131d3df0a..7370cd432a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8010.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8010.json
@@ -1 +1 @@
-{"VIAGRA": 23.9103810965175, "null": 4.393233777036584}
\ No newline at end of file
+{"null": 1.2340368322522348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8011.json
index 0d022125860..030666f2ec4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8011.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8011.json
@@ -1 +1 @@
-{"ABILIFY": 163.82787596914008, "ARIPIPRAZOLE": 274.25936814407856, "CICLOSPORIN": 4.03073006221037, "FIASP": 53.12841230499329, "NOVORAPID": 7.985875415631403, "XELJANZ": 1.6043743055533288}
\ No newline at end of file
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8012.json
index e926dbabb5a..aa8e1cf6114 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8012.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8012.json
@@ -1 +1 @@
-{"null": 1.504439644647552}
\ No newline at end of file
+{"ACLIDINIUM": 140.08611178974064, "ANORO": 7.376806018305943, "AVAMYS": 124.56594544312748, "BUDESONIDE": 65.23221288024948, "COMIRNATY": 0.0280531722821777, "DEXAMETHASONE": 2.3889774271892508, "EFAVIRENZ": 9.926621125720963, "FASENRA": 49.43111372203657, "FLUTICASONE": 37.72626133614623, "IBUPROFEN": 3.6454367159063694, "LEVOFLOXACIN": 1.8623988304955372, "MEPOLIZUMAB": 5.163375384250025, "METHOTREXATE": 11.940371747380482, "NUCALA": 86.44376309799632, "OMALIZUMAB": 15.992216502929272, "PANTOPRAZOLE": 15.0136011593907, "XOLAIR": 5.865389581311857, "null": 0.3923763803303555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8013.json
index f6536cd7d1a..daebb463bca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8013.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8013.json
@@ -1 +1 @@
-{"AERIUS": 13.03801580911446, "CIMZIA": 1.4289748023517843, "COSENTYX": 1.541645959682182, "ENBREL": 3.237458013278137, "EYLEA": 4.799985466043739, "KEPPRA": 5.1164702389122825, "LANTUS": 2.1525876210694275, "NOXAFIL": 44.95315197238797, "OLANZAPINE": 1.9535219250884828, "PEGASYS": 4.127230288387025, "PEGINTRON": 7.002435721320284, "RASAGILINE": 305.2553639664196, "SIMPONI": 4.697098877278535, "STELARA": 5.091447313510626, "STIVARGA": 3.411395627791608, "SUBOXONE": 18.095778640363644, "VIMPAT": 11.11257082977158, "null": 1.1386006792814576}
\ No newline at end of file
+{"COMIRNATY": 0.7333607249480194, "ENTRESTO": 5.141645180688413, "KEPPRA": 2.2748389185200524, "SPIKEVAX": 0.2768928881751667, "TOZINAMERAN": 0.6400463132301167, "VAXZEVRIA": 0.2220865080108875, "null": 3.15523235895123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8014.json
index 9dcf6016602..5c0af669cf7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8014.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8014.json
@@ -1 +1 @@
-{"BRIVARACETAM": 625.9010999964784, "null": 2.301578549087566}
\ No newline at end of file
+{"SUBOXONE": 86.29154471428319, "null": 1.2190407829362462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8015.json
index 6ae14c8fd85..d475ad2948b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8015.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8015.json
@@ -1 +1 @@
-{"ENTYVIO": 2993.9478795698474}
\ No newline at end of file
+{"CICLOSPORIN": 4.621690052193728, "NUCALA": 12.097095098089298, "ZOSTAVAX": 11.237557125332168, "null": 1.2845024892234889}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8016.json
index 45b738a04be..265062e048e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8016.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8016.json
@@ -1 +1 @@
-{"LEVETIRACETAM": 10.204610223234935, "null": 3.6945677666643375}
\ No newline at end of file
+{"null": 1.5019579546637485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8017.json
index f6425e66920..841ece29a25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8017.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8017.json
@@ -1 +1 @@
-{"ACLIDINIUM": 1.3665837301103836, "ADALIMUMAB": 1.3798194435197784, "AFINITOR": 1.2273278162586287, "AIMOVIG": 3.885866496724712, "ALEMTUZUMAB": 2.1095828872050557, "ANAKINRA": 1.7336617852159504, "APIDRA": 2.578719328131786, "ARANESP": 18.615198280850112, "ARAVA": 1.4086612598344102, "ARIPIPRAZOLE": 2.7355636651722373, "AUBAGIO": 1.634145624684093, "AVASTIN": 1.09401476588238, "AZATHIOPRINE": 1.2755566376319791, "BARACLUDE": 9.067227968088512, "BASILIXIMAB": 3.120586472987656, "BEVACIZUMAB": 1.871895637273969, "BORTEZOMIB": 4.563276934575213, "BOSULIF": 1.0444345582013843, "BOSUTINIB": 6.532499055980485, "BOTULINUM": 2.9826001453295845, "BUPIVACAINE": 9.231388280865772, "BUPRENORPHINE": 1.2571748216860867, "CAPECITABINE": 1.6932171743652282, "CASPOFUNGIN": 1.7440925304205366, "CELLCEPT": 1.1466446843062863, "CICLOSPORIN": 4.000878507081898, "CIMZIA": 1.9276462562168344, "COSENTYX": 2.22522123528002, "CYMBALTA": 1.439395635616229, "CYTARABINE": 2.071291989921132, "DABRAFENIB": 6.037042566921579, "DAPAGLIFLOZIN": 3.1790997495259634, "DARZALEX": 1.917293531002567, "DASATINIB": 11.392688160475322, "DENOSUMAB": 2.5901418770560047, "DEXAMETHASONE": 2.30462599334402, "DOCETAXEL": 1.1152073368909396, "DUPIXENT": 3.349835825989292, "EFAVIRENZ": 1.1061587429029078, "EMTRICITABINE": 1.3063934804203674, "ENBREL": 5.330041749263865, "ENTECAVIR": 6.628839912534524, "ENTYVIO": 1.8119133938874723, "EPOETIN": 9.214228158083106, "ERLEADA": 1.4363493544317598, "ESOMEPRAZOLE": 1.1931528498436812, "EVEROLIMUS": 1.6195801323144077, "EVRA": 7.472287871091993, "FENTANYL": 1.5897970470101388, "FLUTICASONE": 6.34188033080476, "GLIVEC": 5.865927545672381, "HEMLIBRA": 3.0126749314159555, "HEPSERA": 8.233763100962967, "HUMAN": 1.600720426800562, "HUMIRA": 1.460664686682347, "ICLUSIG": 2.0393038060943285, "IMATINIB": 7.140173436846499, "INFLIXIMAB": 4.048022666873796, "INSULIN": 1.6359686851039592, "INSUMAN": 6.439673970069999, "IRINOTECAN": 2.702430180870288, "JAKAVI": 2.9197190582334964, "KYMRIAH": 1.191074792397031, "LACOSAMIDE": 4.123239760761429, "LAMIVUDINE": 1.2322338458039137, "LANTUS": 1.198426560629187, "LATUDA": 2.0228410513480406, "LEFLUNOMIDE": 7.381814840207876, "LEVETIRACETAM": 2.496085329388006, "LINACLOTIDE": 44.45792970260735, "LURASIDONE": 7.96995221824886, "MABTHERA": 1.5881626333975718, "MELATONIN": 4.485331955666212, "MEPOLIZUMAB": 2.1503065250481885, "METHOTREXATE": 3.5144034360343825, "MIDAZOLAM": 2.3633189408760296, "MIMPARA": 1.4083921958182055, "MIRCERA": 5.085444742010496, "MULTAQ": 1.665984282581103, "MYCOPHENOLATE": 1.390784676424461, "NEORECORMON": 49.68076132999248, "NEULASTA": 5.526907376088044, "NILOTINIB": 10.967238887376364, "NOVOSEVEN": 42.53762691843345, "NPLATE": 83.09796888638398, "NUCALA": 3.2429499302590523, "OLANZAPINE": 1.3685169286886203, "OMALIZUMAB": 3.8019431678204407, "PAZOPANIB": 6.040715336343409, "PEGASYS": 1.1560601273801283, "PEGINTRON": 1.393084576320316, "PEMETREXED": 2.603158947398427, "PREGABALIN": 1.5347166604676123, "PROPRANOLOL": 3.0145779116792286, "RELVAR": 1.8449291171617253, "REMICADE": 4.674408038362124, "REVLIMID": 1.2177298710642444, "RIBAVIRIN": 1.7776356728938976, "RIBOCICLIB": 2.8099632725825394, "RITUXIMAB": 1.7889557839967425, "RUXOLITINIB": 7.238686517410013, "SIMPONI": 5.767405318091572, "SOLIRIS": 1.730699506948437, "SPRYCEL": 4.488711423594883, "STELARA": 14.964551820009689, "TASIGNA": 2.204898237344297, "TELITHROMYCIN": 129.52114819956003, "TOUJEO": 4.557087721233061, "TOVIAZ": 4.108954361501141, "TRAMETINIB": 8.513841285544412, "TREMFYA": 6.795064437110409, "TWINRIX": 5.992508170172144, "UMECLIDINIUM": 5.102463532025023, "VEKLURY": 8.776703326529509, "VEMURAFENIB": 6.2988866555371175, "VIREAD": 1.0876069035569422, "VORICONAZOLE": 2.779059586604084, "XYREM": 1.7465624636796564, "null": 1.006764815859677}
\ No newline at end of file
+{"AVAMYS": 33.29223167751361, "SUTENT": 3.333085646932914, "null": 3.347066352125269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8018.json
index 1c750e33f24..eefe5d523b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8018.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8018.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 10.908461571499792, "DAPTOMYCIN": 385.6011702657819, "FIRDAPSE": 85.94966454681091, "HUMALOG": 9.70174829135984, "PEGASYS": 2.0026783142203635, "null": 1.0771719948320435}
\ No newline at end of file
+{"null": 7.971546220160108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8019.json
index 0df57cbc08d..ce1f362d4b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8019.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8019.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 3.769482228217407, "KEYTRUDA": 2.296364519186749, "null": 9.812603943749654}
\ No newline at end of file
+{"null": 0.7163965810284204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/802.json
index 03b6a95f5e5..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/802.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/802.json
@@ -1 +1 @@
-{"KYMRIAH": 203.59502564334872}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8020.json
index f80dd3771d9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8020.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8020.json
@@ -1 +1 @@
-{"null": 5.026191923702681}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8021.json
index 19402c6315a..865bafcd71b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8021.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8021.json
@@ -1 +1 @@
-{"AIMOVIG": 20.63305862345607, "BENLYSTA": 3.0257997701899004, "BUDESONIDE": 2.140309438262549, "CARBIDOPA": 52.16352264268834, "CIMZIA": 13.943648782602017, "COMTAN": 81.8669098850534, "COSENTYX": 21.37171415345446, "ENBREL": 3.298332489938167, "ENTACAPONE": 174.86863291804755, "ENTYVIO": 2.5688036292302967, "FAMPYRA": 10.486372404460942, "FASENRA": 12.355770217074172, "FENTANYL": 1.410202381569699, "FIRDAPSE": 64.89857066725571, "HUMIRA": 17.508444467131778, "LEVODOPA": 176.43122478116686, "NUCALA": 1.719439840415968, "OMALIZUMAB": 2.66209341203168, "RINVOQ": 4.188111256097998, "SIMPONI": 2.664166430069389, "SKYRIZI": 65.13614588318256, "SOLIRIS": 4.101116030953178, "SPINRAZA": 12.41470003414732, "STALEVO": 38.01429181564257, "STELARA": 5.224574648637132, "XELJANZ": 3.0174436655285883, "XOLAIR": 1.455418448150905}
\ No newline at end of file
+{"null": 1.8262809498483104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8022.json
index 76d14db0cc1..1aff06d385e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8022.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8022.json
@@ -1 +1 @@
-{"ABASAGLAR": 27.087702835363736, "ABILIFY": 1.499691287114503, "AERIUS": 1.4656912114926417, "AIMOVIG": 1.5419934844040213, "AVAMYS": 1.5119376031044514, "BENLYSTA": 3.927393154954128, "BRINTELLIX": 3.3631327178134267, "BRIVARACETAM": 12.308380398785625, "BRIVIACT": 2.543404012021999, "BUPRENORPHINE": 1.3477892617236191, "CHAMPIX": 2.291988596302023, "CIALIS": 5.395926926585034, "DARZALEX": 1.523572420280345, "DESLORATADINE": 6.18754248686704, "DUORESP": 19.4351307566344, "EPIDYOLEX": 31.182571112175136, "ESOMEPRAZOLE": 1.488335910169632, "EVRA": 2.855973301553378, "FAMPYRA": 1.5026802193413504, "FASENRA": 1.357624915017012, "FULVESTRANT": 1.0024032736095687, "GREPID": 25.80951651850826, "HARVONI": 2.027770948388397, "HUMAN": 11.606294007150304, "HYDROCHLOROTHIAZIDE": 4.561638438198443, "IBRANCE": 1.108489308458751, "IRBESARTAN": 4.408580087441388, "JAKAVI": 1.9692756163617775, "JARDIANCE": 1.3314148432855113, "KALETRA": 4.643350187378398, "LATUDA": 3.0705175838565784, "LIXIANA": 1.2754049453248215, "LOPINAVIR": 36.709231936076414, "LYRICA": 1.821775244220042, "MEPOLIZUMAB": 1.2081458309306807, "NPLATE": 1.0512022962700804, "NUCALA": 1.705738108723021, "OCEAN": 48.33567229941479, "REVATIO": 2.610983391234152, "RIBAVIRIN": 1.1372422472282286, "RINVOQ": 1.835354745456756, "SILDENAFIL": 1.3695124762114184, "SOMATROPIN": 3.0383413805651585, "STELARA": 1.771372592010062, "SUBOXONE": 5.337789109114392, "TOUJEO": 1.5359834071733336, "TRELEGY": 1.1686301303283857, "TREMFYA": 4.6280133893951465, "VIAGRA": 4.223510357457662, "VIMPAT": 2.2983915736907807, "XELJANZ": 4.032725508487449, "XYREM": 13.325031925648712, "null": 2.3918530538253098}
\ No newline at end of file
+{"ARAVA": 6.7830602865765455, "AVAMYS": 23.824949685490655, "BENLYSTA": 20.443250103552167, "COMIRNATY": 0.1692229313517229, "PEGASYS": 3.2651175792031752, "VAXZEVRIA": 0.2031724387170827, "null": 0.8306498229707753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8023.json
index 888aa52bafd..308ebe6c5e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8023.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8023.json
@@ -1 +1 @@
-{"ABILIFY": 4.841348670567941, "ACLIDINIUM": 43.81347348211298, "ANORO": 3.964822024964884, "ARIPIPRAZOLE": 1.3285816348133774, "AUBAGIO": 1.4955786048079538, "BENLYSTA": 6.063781065209198, "BRILIQUE": 10.719597811955936, "BRINTELLIX": 18.17366649136578, "BYDUREON": 6.06882401555604, "CIMZIA": 2.5274050588327457, "CLOPIDOGREL": 1.5111446067547545, "FAMPRIDINE": 37.72586113632104, "FASLODEX": 1.4746301840115588, "FORXIGA": 5.789759683461301, "HARVONI": 5.07525202273341, "HIZENTRA": 9.459249774535277, "IRESSA": 4.548772475714912, "JANUVIA": 1.2865981356323306, "KEPPRA": 1.309375393180748, "LATUDA": 33.821684600323465, "LEVETIRACETAM": 2.247097765317061, "LIXIANA": 3.9256694180937184, "MEPOLIZUMAB": 2.815014678550443, "NUCALA": 4.22584739676654, "OLANZAPINE": 1.4880316928673338, "OPSUMIT": 3.0212992698945387, "PANTOPRAZOLE": 4.831832781075586, "RELVAR": 15.072118274292484, "RIBAVIRIN": 3.754166716740325, "RINVOQ": 1.988347892818974, "SIMPONI": 3.210780958326456, "STALEVO": 11.894260365424236, "STELARA": 1.9955846516676752, "TRELEGY": 11.31408915890956, "TREMFYA": 17.130609920452333, "null": 1.8157759132079403}
\ No newline at end of file
+{"COMIRNATY": 3.5272161810698703}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8024.json
index d9af7e5f805..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8024.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8024.json
@@ -1 +1 @@
-{"ABILIFY": 3.113166326444243, "BRINTELLIX": 6.554115589375809, "CINRYZE": 677.5994164670113, "HIZENTRA": 11.00637861506064, "KEPPRA": 2.485814916004861, "MIDAZOLAM": 11.153434315403125, "OPSUMIT": 32.7635883429137, "TRACLEER": 3.9962170262754384, "null": 1.8451282344666924}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8025.json
index 1f7ef5c1e10..eb7165f833e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8025.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8025.json
@@ -1 +1 @@
-{"ABILIFY": 1.478544471741448, "ACLIDINIUM": 34.8688141095107, "AUBAGIO": 1.31067280299122, "AVAMYS": 2.307831217583779, "BENLYSTA": 11.487210344146284, "BRAFTOVI": 2.5810145777291447, "BRINTELLIX": 1.717574056749091, "BRIVIACT": 31.92832533302308, "BUPRENORPHINE": 2.5815328629074745, "CIMZIA": 28.252553189264148, "EVENITY": 6.469732792247984, "FIRDAPSE": 7.525964569882879, "HIZENTRA": 20.138043522854318, "HUMAN": 3.219678766075916, "IKERVIS": 52.68667732857445, "KEPPRA": 4.179171954744983, "LATUDA": 34.15821001601951, "LUPKYNIS": 60.49324747626236, "NUCALA": 11.651533274925027, "OCALIVA": 57.92968715427239, "OPSUMIT": 2.640663319889721, "PANTOPRAZOLE": 5.390020646762437, "PRIVIGEN": 4.822116494087546, "RELVAR": 9.036383435462415, "SUBOXONE": 14.149536247408417, "TERROSA": 62.73146371117658, "TRELEGY": 5.817377346601875, "TREMFYA": 4.060989595887197, "VIMPAT": 8.308937075724902, "null": 1.6913680878763222}
\ No newline at end of file
+{"null": 2.701416971409917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8026.json
index c9833c4974c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8026.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8026.json
@@ -1 +1 @@
-{"SUBOXONE": 241.75796663131783}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8027.json
index 27286586697..c0a5e9f5891 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8027.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8027.json
@@ -1 +1 @@
-{"ABATACEPT": 1.1223878376729957, "ABILIFY": 2.293477831493164, "ACCOFIL": 33.217418955752905, "ACTOS": 1.9995305019721836, "ADALIMUMAB": 2.5176123284837675, "ADCIRCA": 1.4698301087572874, "ADEMPAS": 3.923727335789287, "AGOMELATINE": 17.17513717426437, "AIMOVIG": 1.5680473577587442, "AMGEVITA": 24.78416704670003, "AMIKACIN": 3.1886694767922874, "ANAKINRA": 3.1689852155767, "APREPITANT": 1.567246901925814, "APROVEL": 2.7032032773845627, "ARANESP": 3.1108143398791457, "ARAVA": 2.251893454637893, "ARIPIPRAZOLE": 2.1016553052772387, "AVONEX": 6.185364191619148, "AZACITIDINE": 2.171243752700478, "AZATHIOPRINE": 1.853099331309021, "BEVACIZUMAB": 3.0047148341076952, "BINOCRIT": 29.646928610442718, "BLINATUMOMAB": 5.974557480445643, "BORTEZOMIB": 10.52700661531997, "BOSENTAN": 5.790961078378302, "BOSUTINIB": 17.121401578344823, "BOTULINUM": 3.487984772207718, "BRIVARACETAM": 3.3030826995273275, "BUPIVACAINE": 12.400801590646443, "BUSULFAN": 2.042154624941661, "CAELYX": 1.639759535263836, "CANCIDAS": 2.252243678069898, "CAPECITABINE": 1.2952720574595094, "CAPSAICIN": 153.36883556698533, "CARFILZOMIB": 15.594602255416696, "CARMUSTINE": 2.868619613134332, "CASPOFUNGIN": 9.570444032361396, "CICLOSPORIN": 3.615980035467321, "CLOFARABINE": 9.934147011283091, "COAPROVEL": 4.580113763582156, "COSENTYX": 3.606394028063796, "CUBICIN": 1.7135768453839837, "CYTARABINE": 4.496792943266767, "DACLATASVIR": 4.348659203762147, "DAKLINZA": 3.9449106387315753, "DAPTOMYCIN": 21.41200674906068, "DASATINIB": 7.938366015314968, "DEXAMETHASONE": 4.149429038144135, "DOXORUBICIN": 2.0900653995288225, "EFAVIRENZ": 1.4471288670702531, "ELBASVIR": 381.91282480365993, "ENBREL": 3.2225515381817025, "ENTYVIO": 8.90832543374933, "EPCLUSA": 1.2931109844396125, "EVENITY": 1.4993101636409345, "EVEROLIMUS": 2.3991295398331345, "FAMPYRA": 17.983094097257837, "FENDRIX": 36.52501155175752, "FENTANYL": 1.8910069564203449, "FILGRASTIM": 7.107143970973526, "GANCICLOVIR": 1.576598097640761, "GLIVEC": 1.913469651192108, "GLUCAGON": 4.22074370129061, "HARVONI": 3.3262392671171157, "HEPSERA": 2.715086410649297, "HUMAN": 13.877412348139584, "IBUPROFEN": 1.596186386959904, "ICATIBANT": 77.49263385000029, "ICLUSIG": 6.667315586010314, "IMATINIB": 9.308598914826076, "INFERGEN": 18.697310855265982, "INFLIXIMAB": 3.5649675891777286, "INTERFERON": 9.763489066226768, "IRINOTECAN": 1.2324772498753034, "JAKAVI": 3.9520866026226575, "JETREA": 19.68971586657152, "KEPPRA": 1.2910230745331686, "KETOCONAZOLE": 12.926076507049508, "KIOVIG": 1.65533303359995, "KUVAN": 8.788457364335828, "KYMRIAH": 5.525898789947751, "KYPROLIS": 2.2703102378504654, "LACOSAMIDE": 3.9451058821642935, "LEVETIRACETAM": 3.371514786742034, "LYRICA": 1.3749611760420786, "MEKINIST": 1.37098202287173, "MELATONIN": 1.2922680685827113, "MICAFUNGIN": 9.206278891030497, "MICARDIS": 2.519897007988937, "MIDAZOLAM": 1.6116105136692598, "MIMPARA": 5.927293972471666, "MIRCERA": 4.787904904196162, "MYCOPHENOLATE": 4.002827639848039, "NEULASTA": 4.491404668802841, "NILOTINIB": 7.511798336203002, "NITRIC": 40.36109660048658, "NIVESTIM": 16.099585110706617, "NOT": 1.5805213004589982, "NOVOSEVEN": 2.6224624656119526, "NOXAFIL": 1.5021244043382227, "NPLATE": 7.145311460460656, "OLANZAPINE": 2.181324211627683, "OLYSIO": 2.743193873313693, "OMALIZUMAB": 1.3525394458610136, "OPSUMIT": 6.254385832795299, "PEGASYS": 3.5095080434469907, "PEGINTERFERON": 7.352327101590116, "PEGINTRON": 1.6058707714418023, "PEMBROLIZUMAB": 6.449377838043633, "PREGABALIN": 1.501193006948602, "PRITOR": 13.038655792751152, "REBETOL": 1.7492224392934996, "RETACRIT": 35.2145068528249, "REVLIMID": 3.0034351129858945, "RIBAVIRIN": 4.367961425666942, "RITUXIMAB": 2.4078835683234185, "ROACTEMRA": 1.7315259067002926, "RUBRACA": 1.5265282823613944, "RUFINAMIDE": 34.21516320776984, "RUXOLITINIB": 7.885079999042761, "SILDENAFIL": 2.349940471280815, "SIMPONI": 1.8248512026774724, "SOLIRIS": 1.3251335526917842, "SOVALDI": 1.6397204861316128, "SPRYCEL": 4.272067117253211, "STELARA": 5.081022335905902, "TASIGNA": 2.4665283458895737, "THALIDOMIDE": 9.953902823222815, "TOBRAMYCIN": 3.680560491155068, "TOCILIZUMAB": 2.250168461349831, "TRACLEER": 2.2861668064969507, "TREMFYA": 2.1615537409863186, "TWINRIX": 12.093218545721088, "VORICONAZOLE": 2.206788399979437, "XOLAIR": 1.5550234332940678, "YESCARTA": 2.5553856275398177, "ZARZIO": 5.865173859320756}
\ No newline at end of file
+{"JANUMET": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8028.json
index e862245f4ad..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8028.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8028.json
@@ -1 +1 @@
-{"AIMOVIG": 9.812814041886568, "ALEMTUZUMAB": 5.031594306155249, "ALIMTA": 5.731171086318192, "ALPELISIB": 19.354323675007983, "ARIPIPRAZOLE": 1.2684368312923195, "AVASTIN": 5.44805667250569, "AXITINIB": 35.51013363548202, "AZACITIDINE": 8.661754146913392, "BEVACIZUMAB": 15.221348171998528, "BORTEZOMIB": 31.07916673348921, "BOTULINUM": 6.339146741001509, "CAPECITABINE": 9.615163808295044, "CARFILZOMIB": 65.97417361169826, "CARMUSTINE": 13.8483616178848, "CELLCEPT": 4.381579832242541, "CICLOSPORIN": 1.1397221866467848, "COBIMETINIB": 27.37242856250962, "CYTARABINE": 7.576436500916198, "DABRAFENIB": 40.26413926134357, "DENOSUMAB": 10.429781614492136, "DEXAMETHASONE": 5.6667891551650245, "DOCETAXEL": 7.711904578613736, "DOXORUBICIN": 8.310131859334078, "ENTYVIO": 3.849816507523841, "FILGRASTIM": 13.53813885111127, "FULVESTRANT": 9.39073316115756, "HERCEPTIN": 3.295312851944208, "HUMAN": 14.333179066830636, "HUMIRA": 4.228867058271397, "IBRUTINIB": 25.24757006552831, "IBUPROFEN": 1.83405505740317, "ICLUSIG": 5.7934551053142505, "IRINOTECAN": 13.26666594775564, "KEYTRUDA": 15.82749299302865, "KISQALI": 7.451667199649868, "KYMRIAH": 4.801821557044752, "KYPROLIS": 14.653631436557214, "LEVETIRACETAM": 1.8248167680300007, "LUTETIUM": 29.74898920833145, "MABTHERA": 4.146999215443456, "MEKINIST": 2.9612114573624844, "METHOTREXATE": 1.6838814369227917, "OBINUTUZUMAB": 17.4979119892943, "OMALIZUMAB": 2.878688078511013, "PACLITAXEL": 17.959005945723682, "PANITUMUMAB": 74.4823847479434, "PAZOPANIB": 13.153834687498836, "PEMBROLIZUMAB": 97.89781064909909, "PEMETREXED": 19.845889263031644, "RIBOCICLIB": 45.722913034238296, "RITUXIMAB": 9.660154056827263, "RUBRACA": 15.494220586701829, "RUXOLITINIB": 22.2700994895276, "SOTORASIB": 73.56637711356981, "TRODELVY": 9.699055877011729, "VECTIBIX": 48.86753638740368, "VOTRIENT": 1.370836160197242, "XOLAIR": 1.063222270064397, "YESCARTA": 3.696353065879283}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8029.json
index 3cca8f89ff4..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8029.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8029.json
@@ -1 +1 @@
-{"ABILIFY": 34.178912544689204, "ACLASTA": 42.750243205747225, "APIDRA": 4.782710996071542, "BUPRENORPHINE": 29.20837035941515, "FORTIMEL": 1213.750854150354, "HUMALOG": 1.940093127967785, "IBRANCE": 1.05345034400645, "QUTENZA": 69.85504554084534, "STELARA": 1.214116158888818, "SUTENT": 1.378959519317738, "XELJANZ": 1.2725224721604385, "XOLAIR": 1.892407030522719, "null": 1.4236386822220353}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/803.json
index 5d7e95e036c..47ba27540fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/803.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/803.json
@@ -1 +1 @@
-{"KYMRIAH": 1929.585872279043}
\ No newline at end of file
+{"CUBICIN": 2551.583420968558, "DAPTOMYCIN": 1146.818714423247, "null": 0.2118259800632536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8030.json
index f51819f9262..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8030.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8030.json
@@ -1 +1 @@
-{"COVID19": 2.36706499947388, "TOZINAMERAN": 1.3996302947515922, "null": 1.7038144939747206}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8031.json
index b4963bad2bc..addfaf48639 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8031.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8031.json
@@ -1 +1 @@
-{"null": 1.2217764978487888}
\ No newline at end of file
+{"ABACAVIR": 0.0677122119068604, "ABASAGLAR": 0.6790273426257368, "ABATACEPT": 5.975373607677288, "ABILIFY": 0.2516761086969358, "ACETAMINOPHEN": 11.812767047058896, "ACLASTA": 1.5361224812054295, "ACLIDINIUM": 0.9792987524616528, "ACTOS": 1.008170229187337, "ADALIMUMAB": 1.0277157825767544, "ADCIRCA": 0.5411630010221562, "ADEMPAS": 1.9999884486087105, "AERIUS": 1.0297735326481017, "AFINITOR": 1.061627553135272, "AIMOVIG": 1.1955453885944956, "ALEMTUZUMAB": 0.6258349923554191, "AMBRISENTAN": 1.5690101132029364, "AMINOSALICYLIC": 0.5345163674484074, "ANAKINRA": 0.6509221662155581, "ANORO": 0.8004484887609992, "APIDRA": 0.3709472020855395, "APIXABAN": 0.0851701996731517, "APREMILAST": 0.9115976044077976, "ARANESP": 0.222016312177673, "ARAVA": 1.465499628768948, "ARIPIPRAZOLE": 0.2781192088486012, "AUBAGIO": 1.3348802355173246, "AVAMYS": 1.2486144605193077, "AVANDIA": 0.065193014913845, "AVASTIN": 0.4720671011385793, "AZATHIOPRINE": 0.5379517632739675, "BEDAQUILINE": 0.2581133751429643, 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3.5087013986206883, "XTANDI": 0.7809037204768442, "XYREM": 1.3232509069307308, "ZOSTAVAX": 0.5090535312950921, "ZYPREXA": 0.2762459847776881, "null": 0.6157011447856449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8032.json
index 7c4fdfbde97..e94e00ba1c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8032.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8032.json
@@ -1 +1 @@
-{"null": 2.2142953271576955}
\ No newline at end of file
+{"ARANESP": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8033.json
index 6c282f0ffa5..bf6969fee31 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8033.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8033.json
@@ -1 +1 @@
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\ No newline at end of file
+{"CICLOSPORIN": 137.29411995514673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8034.json
index abc5455ef15..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8034.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8034.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 611.4963049857162}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8035.json
index 712dd626728..7cc9ee44e95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8035.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8035.json
@@ -1 +1 @@
-{"null": 2.0925266228089137}
\ No newline at end of file
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0.6210977524442157, "TASIGNA": 0.4879549326817004, "TAXOTERE": 0.6519641662664217, "TECFIDERA": 0.5802351249382589, "TEDUGLUTIDE": 0.4401217155089333, "TEGAFUR": 1.4515040506957764, "TELAPREVIR": 0.7041512509215299, "TELMISARTAN": 0.6318288444635103, "TEMODAL": 0.740085307932011, "TEMOZOLOMIDE": 0.8823601604983424, "TENOFOVIR": 0.6936287017159954, "TEPMETKO": 3.5380030778930496, "TERIFLUNOMIDE": 0.4220229854391913, "TERIPARATIDE": 1.207031629804894, "TERROSA": 2.087133447193419, "TESTOSTERONE": 0.1310801510613606, "THALIDOMIDE": 0.3213354952540616, "THERAPEUTIC": 1.5789757911569255, "THERAPY": 0.8025731415963632, "THIOTEPA": 0.2939106839591401, "TICAGRELOR": 0.5067614193507335, "TIGECYCLINE": 1.4518752611243375, "TIVICAY": 0.5352278458674092, "TOBRAMYCIN": 0.4608863523100148, "TOCILIZUMAB": 0.1325475550425714, "TOPOTECAN": 0.4681050457304607, "TORISEL": 0.4451148272553736, "TOUJEO": 0.2961049063129662, "TOVIAZ": 0.2511084121443542, "TOZINAMERAN": 1.280582336850763, "TRABECTEDIN": 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"VELMETIA": 0.6790275136730072, "VELTASSA": 0.4834834088515274, "VEMLIDY": 0.3173482043626774, "VEMURAFENIB": 0.4577316582451775, "VENCLYXTO": 0.4025158940907562, "VENETOCLAX": 0.352883215464974, "VERZENIOS": 0.8548115837099717, "VFEND": 0.2653695760734577, "VIAGRA": 0.1770211960683504, "VICTOZA": 2.8461628332600624, "VICTRELIS": 0.6221172904284825, "VIDAZA": 0.5030268921297217, "VILDAGLIPTIN": 0.4462933722436152, "VIMPAT": 0.577191443617877, "VIRAMUNE": 0.6456166294062416, "VIREAD": 0.2590259303502211, "VORICONAZOLE": 0.2367279434621312, "VORTIOXETINE": 2.4313154618103816, "VOTRIENT": 1.3423684064995347, "VYXEOS": 0.2503072949626412, "WAKIX": 1.0754999854422909, "XALKORI": 1.605513235723595, "XARELTO": 0.3619585726362039, "XELJANZ": 0.5251294220372491, "XELODA": 1.611231362497598, "XGEVA": 0.3160942658165641, "XOFIGO": 0.8682185467539608, "XOLAIR": 0.4850993757605357, "XTANDI": 0.9621288060554672, "XYREM": 0.7436357363275267, "YERVOY": 0.4953530708222959, "YESCARTA": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8036.json
index d7e56aeebeb..4e6f15d14d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8036.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8036.json
@@ -1 +1 @@
-{"APIDRA": 3.5401881717143766, "CHAMPIX": 2.370156846381854, "COMTAN": 1.8543081112958897, "COVID19": 2.911761147645873, "ELLAONE": 2.9726951049976704, "EMPAGLIFLOZIN": 13.086715335484769, "FENTANYL": 1.261305293079284, "FIASP": 4.151856781163862, "FORSTEO": 1.227779869648342, "FORXIGA": 11.70840791392076, "HUMALOG": 2.5035340959028383, "INCIVO": 1.210523745238247, "INSULIN": 1.4233083692798736, "JARDIANCE": 15.869570830808316, "LANTUS": 2.5293677589527666, "LATUDA": 1.5154208144211136, "OLANZAPINE": 1.155390552777018, "PEGINTRON": 2.452659173528025, "RELVAR": 2.8741825692157703, "RIBAVIRIN": 1.2046112041010626, "SAMSCA": 10.199955214385623, "SAXENDA": 1.3635934321825085, "TELMISARTAN": 2.6013816464191817, "TOUJEO": 2.8953953280919102, "TOVIAZ": 8.227023601584046, "TOZINAMERAN": 1.4706975090088796, "VAXZEVRIA": 1.6907153535055144, "ZYPREXA": 2.762738917279277}
\ No newline at end of file
+{"APIDRA": 3.484766461910498, "BENLYSTA": 1.971579547076381, "BUDESONIDE": 1.0951095796981545, "BYDUREON": 2.708396451859997, "COMIRNATY": 0.1389795644344668, "CYMBALTA": 0.4954245186090302, "ENTRESTO": 15.058884646759312, "FENTANYL": 2.049831609244244, "IBRANCE": 1.1560893928366185, "INLYTA": 2.3266356243307924, "JARDIANCE": 2.141060471735376, "KEPPRA": 0.9370034944334672, "LANTUS": 1.7722003354447493, "LATUDA": 4.683636252556969, "LYRICA": 4.790168570266594, "PEGASYS": 0.385315015709731, "SHINGRIX": 2.3887158031154905, "SPIKEVAX": 0.1945977274814894, "SUTENT": 0.6125275191442168, "TOZINAMERAN": 3.79826780516198, "TRELEGY": 11.409970443892592, "VAXZEVRIA": 0.0471390214019847, "VIAGRA": 3.817954786452341, "XELJANZ": 2.6828317217502904, "XTANDI": 1.104128925909931, "null": 2.148204446642173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8037.json
index f788199fcca..dc52d32d6a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8037.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8037.json
@@ -1 +1 @@
-{"MMRVAXPRO": 10.518567064610794}
\ No newline at end of file
+{"COMIRNATY": 1.0247530235093136, "null": 1.2754798698693273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8038.json
index 03b778baaf1..0a3b19c8bb3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8038.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8038.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"ARAVA": 17.007737406839695, "null": 0.7606954733080794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8039.json
index 31c0b169c01..1438af22113 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8039.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8039.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0419797819288057}
\ No newline at end of file
+{"ATRIPLA": 0.5754149584849688, "BYDUREON": 9.136114976262574, "COMIRNATY": 0.0621691719210746, "CYMBALTA": 2.0704844970693874, "HUMALOG": 5.253615994472543, "LANTUS": 2.133161663934288, "LYRICA": 7.538275676326467, "SPIKEVAX": 0.1484446904543322, "SUBOXONE": 8.733245554775625, "TOZINAMERAN": 0.8674397042805282, "ZOSTAVAX": 2.794420765883696, "null": 1.679699856333715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/804.json
index 15f67cd95ac..33a815832f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/804.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/804.json
@@ -1 +1 @@
-{"KESIMPTA": 284.462427783172, "RITUXIMAB": 30.99748987430866}
\ No newline at end of file
+{"null": 1.0680910332943785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8040.json
index e73f2b39aee..50ce789aa8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8040.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8040.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 5.004138490426339, "ATRIPLA": 6.744285537957572, "EVENITY": 118.69884794778946, "EVISTA": 79.56931000386388, "FORSTEO": 16.522823903008476, "STRIBILD": 3.348862490082252, "TRUVADA": 2.7155758793026887}
\ No newline at end of file
+{"ARAVA": 1.9701190537959368, "CIMZIA": 2.864564243255378, "COMIRNATY": 0.9796973598558878, "PEGASYS": 1.020932426273596, "SIMPONI": 3.120824705035026, "SPIKEVAX": 0.9490570874459808, "TOZINAMERAN": 2.775880660899674, "VAXZEVRIA": 0.4710206596470006, "null": 0.4326156990406798}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8041.json
index b412e411296..23715273356 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8041.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8041.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 114.0109227821457, "null": 1.359277192537194}
\ No newline at end of file
+{"ABATACEPT": 1.994389785948623, "ABILIFY": 0.1804456425016486, "ACLASTA": 1.5908325713869471, "ADALIMUMAB": 1.0035900561676556, "ADEMPAS": 0.6233180069625346, "AFINITOR": 0.2606378570067593, "AIMOVIG": 2.4735639148079014, "ANAKINRA": 5.963754106146197, "ANORO": 0.4098367200281944, "APIDRA": 0.3690516983234615, "APREPITANT": 1.933581009562371, "ARAVA": 0.5690805423368607, "ATRIPLA": 0.1511792707528143, "AUBAGIO": 0.7555377501935502, "AVAMYS": 0.878396824261828, "AVANDIA": 0.0855271470609558, "AZATHIOPRINE": 0.3554650452131554, "BENLYSTA": 0.5855691321551704, "BIKTARVY": 0.5037141058929112, "BONVIVA": 0.7510102155980491, "BOSULIF": 0.7750975381289384, "BOTULINUM": 29.057180953638422, "BRINTELLIX": 0.2130818980727372, "BUPIVACAINE": 1.527899945380217, "BUPRENORPHINE": 0.1121835957977221, "BYDUREON": 1.429495522539873, "BYETTA": 0.3050211208322843, "CELECOXIB": 1.1608884424376178, "CELLCEPT": 0.2176675029436644, "CERVARIX": 3.2345181669802874, "CHAMPIX": 0.6001739126633522, "CICLOSPORIN": 0.2327053443205481, "CIMZIA": 0.4882866427557764, "CLOPIDOGREL": 0.4036093122194608, "COMBIVIR": 0.3373740863530696, "COMIRNATY": 2.101653841042983, "COMTAN": 0.8780774614617434, "COSENTYX": 2.582355420226921, "CYMBALTA": 0.4310454360511375, "DEXAMETHASONE": 0.2716001885262455, "DULOXETINE": 0.6991878968712815, "ELIQUIS": 0.2599761985238662, "ENBREL": 0.612879560681116, "ENTRESTO": 0.1358022756106888, "ENTYVIO": 0.5628896701095571, "ERELZI": 2.245197207127247, "ERENUMAB": 2.195195366040987, "ESBRIET": 0.4287441434403262, "EVENITY": 1.4469295549759404, "EVISTA": 0.3195382914325058, "EXFORGE": 0.5798992045517853, "EXJADE": 0.2195531308573993, "FAMPYRA": 0.3149511319134744, "FASENRA": 0.5852903752380169, "FASLODEX": 0.7105475758196663, "FENTANYL": 0.4427352038660239, "FIRDAPSE": 1.098336332533983, "FLEBOGAMMA": 1.8158540068115097, "FLUCELVAX": 1.756323877326592, "FORSTEO": 1.6710409433242668, "FORXIGA": 0.4222642734396123, "FULVESTRANT": 0.3648437527727874, "GALVUS": 0.4902634114428464, "GARDASIL": 2.330338741475777, "HIZENTRA": 0.9076209993780588, "HUMALOG": 0.1417194132759556, "HUMAN": 0.3350596581535657, "HUMIRA": 2.4570532986957287, "HYDROCORTISONE": 1.05156565804419, "IBRANCE": 0.5084977957957619, "IBUPROFEN": 0.7648786837077028, "INLYTA": 0.2885562424969263, "JANUMET": 0.2376146485078802, "JANUVIA": 0.2413401061590222, "KEPPRA": 0.0763183324366714, "KEYTRUDA": 0.2696247900276811, "KIOVIG": 0.972898129953226, "LANTUS": 0.1868562202089174, "LATUDA": 0.3471485372296123, "LEFLUNOMIDE": 1.3676515936772642, "LEMTRADA": 0.8327978836544122, "LEVOFLOXACIN": 0.4492731307173827, "LYRICA": 0.8168291750755429, "MEKINIST": 0.2037513278493515, "MENVEO": 2.168382562315345, "MEPOLIZUMAB": 0.4103110438152986, "METHOTREXATE": 0.5030484305039002, "MICARDIS": 0.5834172876586147, "MMRVAXPRO": 0.3773575675261524, "MODERNA": 1.259520802051604, "NAGLAZYME": 0.8338859655493402, "NEULASTA": 0.5215458050501902, "NEXAVAR": 0.179245431706835, "NIMENRIX": 3.660534437370429, "NUCALA": 0.664490224141595, "OCEAN": 15.72842707541396, "OCRELIZUMAB": 2.455179981212995, "OLANZAPINE": 0.1060107978890968, "OMALIZUMAB": 0.4424474399879177, "OPDIVO": 0.2493434862453925, "OPSUMIT": 0.3858096536957773, "PEGASYS": 0.4328424764054816, "PEGINTERFERON": 0.2254803201591884, "PEGINTRON": 0.4012296171918104, "PLAVIX": 0.1607333077584334, "PREGABALIN": 0.321098765613339, "PRIVIGEN": 2.1928169217371267, "RELVAR": 0.4183968947274064, "REVATIO": 0.5553869584688695, "RINVOQ": 0.5560355126774515, "RITUXIMAB": 0.2797198569288908, "ROACTEMRA": 0.2877669416518538, "SAXENDA": 0.1745192194604992, "SHINGRIX": 2.002430105797637, "SILDENAFIL": 0.3516565077292204, "SIMPONI": 0.4657196038282479, "SOLIRIS": 0.4879221268097386, "SPIKEVAX": 1.727745774526185, "SPINRAZA": 1.5418826897218794, "SPRYCEL": 0.2026608087717017, "STELARA": 0.7533055718537817, "STIVARGA": 0.2631081491856974, "SUBOXONE": 0.7060743543039495, "SUTENT": 0.2580400573818797, "TASIGNA": 0.601345877247791, "TIVICAY": 0.8535132315168829, "TOZINAMERAN": 3.566844575803683, "TRACLEER": 0.1818160712303852, "TRELEGY": 0.1890546219400593, "TREMFYA": 0.3487558772692228, "TRULICITY": 0.269291978755139, "TRUVADA": 0.0592385433018323, "TWINRIX": 1.3190023897325145, "VAXZEVRIA": 2.294230055149579, "VIAGRA": 0.3309281220214984, "VOTRIENT": 0.12468670665871, "XELJANZ": 0.9894663132477354, "XOLAIR": 0.5387391300942033, "XTANDI": 0.5784739225744481, "XYREM": 0.5867051315391774, "ZARZIO": 2.236402243869809, "ZOSTAVAX": 1.8035587137825395, "ZYPREXA": 0.2349969107349902, "null": 0.3900857787227184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8042.json
index bb0f10b430d..da5abd50865 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8042.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8042.json
@@ -1 +1 @@
-{"null": 1.7106632264816388}
\ No newline at end of file
+{"CIMZIA": 5.017847706167466, "LANTUS": 6.545082323210983, "SIMPONI": 6.9722765468112, "XELJANZ": 5.402395134667284, "ZOSTAVAX": 7.642314888183717, "null": 1.358681988858233}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8043.json
index 2d66adec518..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8043.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8043.json
@@ -1 +1 @@
-{"null": 2.2450342229325893}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8044.json
index 84c23bfc2a3..acfe7238125 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8044.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8044.json
@@ -1 +1 @@
-{"REMICADE": 69.01151818158482, "null": 1.550336653271205}
\ No newline at end of file
+{"null": 2.386097647336676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8045.json
index 001c09c2354..bde4b3bed47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8045.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8045.json
@@ -1 +1 @@
-{"ELIQUIS": 2.149237577734681, "FORSTEO": 3.730448881944247, "HUMALOG": 2.484660999749372, "JANUVIA": 3.5396585189141927, "LANTUS": 2.446919768280144, "SUBOXONE": 3.469265011896315, "TRELEGY": 12.650415936596234, "VIAGRA": 13.529051263072487, "XELJANZ": 1.3185940869453163, "XTANDI": 2.4759666002173493, "null": 3.4907187593180984}
\ No newline at end of file
+{"AFINITOR": 2.6041519851375607, "ARAVA": 0.243124839707628, "ATRIPLA": 1.024120520801632, "CELLCEPT": 2.0244208474702976, "CICLOSPORIN": 3.5028590842916114, "CLOPIDOGREL": 1.4308377512089094, "COMIRNATY": 0.1062308233511261, "CYTARABINE": 2.7619128609137733, "DEXAMETHASONE": 3.0181827029941792, "EFAVIRENZ": 20.821467831672688, "ELIQUIS": 1.3522129196416406, "ENOXAPARIN": 4.677717287981768, "FENTANYL": 1.4258633302946608, "FORXIGA": 4.206912057893623, "IBRANCE": 0.7750170577175338, "JAKAVI": 2.755357324310602, "JARDIANCE": 3.099005219557937, "KEYTRUDA": 1.2559095607979311, "NOVOSEVEN": 15.89311978233603, "ROACTEMRA": 2.748046739585948, "SPIKEVAX": 0.0737310539782799, "SUTENT": 1.426666245267284, "TASIGNA": 5.091975432360358, "TRUVADA": 0.5884248112624418, "VAXZEVRIA": 0.0795289148653272, "VOTRIENT": 1.981854897057111, "null": 1.5137641453276065}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8046.json
index 93afe0e2e86..9d6b4b779b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8046.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8046.json
@@ -1 +1 @@
-{"AUBAGIO": 3.194567995316621, "AVAMYS": 205.87447492713576, "BUDESONIDE": 17.449373352666097, "ENTRESTO": 17.351382960204543, "MEPOLIZUMAB": 4.860631988550817, "OMALIZUMAB": 29.01714202930412, "VARENICLINE": 251.59142101064495, "XOLAIR": 7.0406736085255845}
\ No newline at end of file
+{"LEVETIRACETAM": 50.15914745594712, "null": 2.182470074446593}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8047.json
index 96bc0a572ad..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8047.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8047.json
@@ -1 +1 @@
-{"AERIUS": 1.6412317625074238, "ALLERGY": 69.15917243321545, "ANORO": 1.7573216123323858, "APROVEL": 1.3452123997466992, "AVAMYS": 3.264730080379355, "BENLYSTA": 1.5896185595234804, "DARZALEX": 2.277238179508255, "ELEBRATO": 31.089914454059905, "FASENRA": 1.6407240948907251, "FASLODEX": 1.9846305208885235, "HYDROCORTISONE": 1.1441042839825908, "INCRUSE": 4.328323319820536, "KESIMPTA": 2.211219098823108, "MENVEO": 1.404637111919131, "NAGLAZYME": 1.0215077048455796, "NUCALA": 1.053737524296006, "OFATUMUMAB": 12.142701430593592, "OMALIZUMAB": 1.734172345471115, "ONCASPAR": 1.596742508298315, "PRIVIGEN": 1.417788789244084, "QUTENZA": 23.15140497049723, "RELVAR": 10.43816140683952, "RITUXIMAB": 2.592024034163344, "RIXATHON": 25.85324246592377, "TOZINAMERAN": 1.5216864894513673, "TRELEGY": 4.503511362282564, "XOLAIR": 4.394188159004771, "XTANDI": 1.0232922704937335, "null": 2.9079386216640515}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8048.json
index fcc716ae6e2..4f6bced115a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8048.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8048.json
@@ -1 +1 @@
-{"SUTENT": 12.909425879042338, "null": 1.137895500228114}
\ No newline at end of file
+{"null": 3.606266839717792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8049.json
index ef28dcdb4cd..3db45412e98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8049.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8049.json
@@ -1 +1 @@
-{"ABILIFY": 3.339873002426077, "ANTIHYPERTENSIVES": 36.33814622424957, "BENLYSTA": 1.2122075262314185, "CAELYX": 2.1973748271421694, "CHAMPIX": 1.118844059238189, "COMIRNATY": 1.51762664465235, "DARZALEX": 1.8160503055407624, "FASENRA": 3.053162379418976, "FASLODEX": 2.2274904493956744, "FLEBOGAMMA": 2.4527997892165545, "GARDASIL": 1.4297742248709826, "HIZENTRA": 2.7145609839018694, "HYDROCORTISONE": 1.4654829571614056, "IBUPROFEN": 2.0623994910531724, "INCRUSE": 1.9014975679098949, "INSULIN": 1.2869973257789094, "KIOVIG": 1.6546102502270663, "KUVAN": 7.929692773991227, "LATUDA": 1.948010275907724, "LEFLUNOMIDE": 1.4476092339973834, "MENVEO": 2.4494990278266755, "MIRCERA": 5.015735851215882, "NEULASTA": 2.137882491376258, "OMALIZUMAB": 2.136943316380054, "PRIVIGEN": 3.108604274761102, "RASILEZ": 1.4696467461384832, "RELVAR": 1.0972620403819189, "RIXATHON": 15.643042117437563, "RUCONEST": 3.8643172316644057, "SUBOXONE": 1.4319047648155332, "TOVIAZ": 1.002205515587376, "TOZINAMERAN": 2.93172380102366, "XOLAIR": 7.456707910602027, "null": 1.840860927536567}
\ No newline at end of file
+{"null": 1.7564868204829724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/805.json
index b8ecb68120a..9f8e8edd480 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/805.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/805.json
@@ -1 +1 @@
-{"CICLOSPORIN": 51.84362451150208}
\ No newline at end of file
+{"NUCALA": 90.44995424394762, "null": 1.1414082821232734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8050.json
index e24ca533f7f..b8f0fd7d619 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8050.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8050.json
@@ -1 +1 @@
-{"ELIQUIS": 22.09944585424404, "SPIKEVAX": 2.1051000148635497, "VAXZEVRIA": 1.251091984783034}
\ No newline at end of file
+{"ARAVA": 0.3676800450051999, "AVASTIN": 14.622785480322582, "CELECOXIB": 11.003400090320032, "CICLOSPORIN": 6.410336387093923, "COMIRNATY": 0.0702001619516476, "EMPAGLIFLOZIN": 26.727844286177287, "FORXIGA": 12.1159002581085, "INVOKANA": 48.16911737572099, "JARDIANCE": 75.11377775754025, "KEYTRUDA": 2.362357341166491, "METHOTREXATE": 2.45867524546414, "MYCOPHENOLATE": 14.529584344702911, "PEGASYS": 1.098369657754427, "PEGINTRON": 3.515391834048868, "ROACTEMRA": 17.43327472683876, "SOLIRIS": 3.522004274252127, "null": 0.6726407102367299}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8051.json
index 2240ba6e152..7b72ae8f909 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8051.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8051.json
@@ -1 +1 @@
-{"NOVORAPID": 119.58125356646327}
\ No newline at end of file
+{"COMIRNATY": 0.4537031926170006, "KEYTRUDA": 15.26776937104628, "null": 0.8964919126420129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8052.json
index f21ef17dd66..db708225178 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8052.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8052.json
@@ -1 +1 @@
-{"ABACAVIR": 7.725832481719602, "ABRAXANE": 2.46024335371934, "ACTRAPID": 1.0408180986510864, "ADCETRIS": 1.8550414610497767, "ADENURIC": 1.075018227139743, "ADVAGRAF": 2.723217135192942, "AFINITOR": 1.7107677740019376, "AFLIBERCEPT": 2.995570907266436, "ALEMTUZUMAB": 1.336353012332996, "ALIMTA": 8.328954663643799, "AMIKACIN": 3.252351557203704, "ANGIOX": 3.440307230696157, "ANIDULAFUNGIN": 2.7263637091714057, "APREPITANT": 1.380831984851673, "APROVEL": 1.7282388486440017, "ARIXTRA": 5.829588616322615, "ARZERRA": 1.7176068103986986, "ASPARAGINASE": 1.791456551143783, "ATEZOLIZUMAB": 1.672501028631293, "AVASTIN": 3.3998015848393264, "AVELUMAB": 1.730030520037842, "AXICABTAGENE": 4.764848267732937, "AZACITIDINE": 10.112357785873856, "AZTREONAM": 1.5827433788313356, "BARACLUDE": 1.1982950412294096, "BASILIXIMAB": 1.1985649610124127, "BAVENCIO": 1.294183451462422, "BELANTAMAB": 6.633606057169947, "BETAFERON": 1.186175830022652, "BEVACIZUMAB": 4.762123677625729, "BINOCRIT": 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2.2857107949690647, "METHOTREXATE": 1.7071811727664317, "MICAFUNGIN": 1.6034752977583695, "MIDOSTAURIN": 4.082471137701314, "MVASI": 4.148706130123995, "MYCAMINE": 4.786201285534131, "MYOCET": 11.619604536662752, "NEORECORMON": 3.402614321255196, "NEULASTA": 1.638302930000063, "NEXAVAR": 1.5430426935758286, "NILOTINIB": 6.080852023815987, "NINLARO": 1.3147200593075192, "NIVESTIM": 2.720000603483483, "NIVOLUMAB": 1.0755536516020614, "NORVIR": 1.2448373734396545, "NOVONORM": 2.3743782240369784, "NOXAFIL": 1.333941458533024, "NPLATE": 7.866046156448394, "OBINUTUZUMAB": 8.375632949669955, "OCTREOTIDE": 1.635834064191351, "OFATUMUMAB": 1.9376367149586389, "OLAPARIB": 8.613044668658455, "OSIMERTINIB": 4.565497674625321, "PACLITAXEL": 2.061608055933207, "PANITUMUMAB": 6.577652329002839, "PANTOPRAZOLE": 1.6191244335972073, "PAZOPANIB": 2.639548826243912, "PEGASPARGASE": 3.039499043319568, "PEGASYS": 4.416026190709739, "PEGFILGRASTIM": 4.760673530303117, "PEGINTERFERON": 6.69414669382517, 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6.670853239012609, "VENETOCLAX": 8.100238912211708, "VFEND": 1.018435316954449, "VIDAZA": 2.1757275131830016, "VOTRIENT": 1.7679245323315411, "VYXEOS": 5.532761549092627, "XARELTO": 1.2856975554674277, "XELODA": 4.976672853500907, "XOFIGO": 6.969837955676304, "YESCARTA": 2.035956666188308, "YONDELIS": 8.658436094116635, "YTRACIS": 33.6963348638808, "ZALTRAP": 4.171631462935892, "ZAVESCA": 2.30505935295198, "ZEVALIN": 23.739532794081796, "ZOMETA": 1.1726539896280772, "ZONISAMIDE": 2.2046385447999604, "null": 1.2615542535233983}
\ No newline at end of file
+{"JARDIANCE": 17.152597385978023, "null": 1.450065862324574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8053.json
index dd4eb09f698..ce13c8673b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8053.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8053.json
@@ -1 +1 @@
-{"COMBIVIR": 73.11391863051134, "null": 2.470150612661808}
\ No newline at end of file
+{"ZOSTAVAX": 24.19358805835653, "null": 0.493927577808986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8054.json
index 9a15c7fb289..9da552d92e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8054.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8054.json
@@ -1 +1 @@
-{"BEVACIZUMAB": 4.079120258028757, "CICLOSPORIN": 1.1964542597180137, "CLOPIDOGREL": 1.400416738616609, "COAPROVEL": 7.531581166139762, "GARDASIL": 2.1534052927377694, "KEPPRA": 1.67560981954535, "MICARDIS": 5.824137463988968, "MMRVAXPRO": 2.4357431484741, "PEGASYS": 3.114171628324546, "PLAVIX": 11.594030724354718, "PREVENAR": 44.74746314121028, "ROTATEQ": 34.92222192097596, "null": 2.431601503245219}
\ No newline at end of file
+{"null": 1.5045972803916627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8055.json
index 21669b84e0e..c7139a8ffa1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8055.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8055.json
@@ -1 +1 @@
-{"ELIQUIS": 1.206751090409544, "ENOXAPARIN": 7.780007914275118, "EXJADE": 3.0095814861494827, "JAKAVI": 29.978813834095117, "NILOTINIB": 15.432165365654727, "NPLATE": 43.84949571751786, "PEGASYS": 1.2995685501767067, "RUXOLITINIB": 30.277601068635413, "STELARA": 1.2239727892658925, "SUTENT": 1.577021136040526, "TASIGNA": 8.865542933185997, "ZYPREXA": 2.285253523483035, "null": 1.5632964454581173}
\ No newline at end of file
+{"JARDIANCE": 176.94216277979285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8056.json
index dd5d41cd9ec..9c5f1162716 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8056.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8056.json
@@ -1 +1 @@
-{"VAXZEVRIA": 2.767703360290368}
\ No newline at end of file
+{"EMEND": 1640.8684551118154, "null": 0.356816801180343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8057.json
index 35a26f75a49..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8057.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8057.json
@@ -1 +1 @@
-{"ARANESP": 1.495418366628502, "AVASTIN": 2.4654395695842592, "CELECOXIB": 9.611690427339337, "COMIRNATY": 1.9467864061356823, "COVID19": 1.828692666278123, "DEXAMETHASONE": 1.6272811989766478, "EVISTA": 8.318057673661865, "FORSTEO": 4.319420273354766, "FULVESTRANT": 5.551954059874265, "PEGINTERFERON": 1.4661821805080348, "PEGINTRON": 1.6769922758037124, "ROACTEMRA": 1.2455116186507893, "VAXZEVRIA": 3.074054912604828}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8058.json
index fe705bcbe8e..188410bff7e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8058.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8058.json
@@ -1 +1 @@
-{"ALIMTA": 30.041564853641983, "KEYTRUDA": 46.02028782073444, "OPDIVO": 42.0414189899959}
\ No newline at end of file
+{"AFINITOR": 6.742873980859075, "AIMOVIG": 8.789803530867989, "ARANESP": 1.165683789724267, "BYDUREON": 23.96399268814435, "CIMZIA": 5.280546999076598, "COMIRNATY": 0.0164859891241452, "COSENTYX": 6.356431679283844, "DEXAMETHASONE": 0.8336959376017558, "DULOXETINE": 2.8449413520991005, "ENOXAPARIN": 3.113041600528252, "EVEROLIMUS": 7.632344285518537, "FASENRA": 6.523692583374997, "HUMALOG": 0.5513287200917134, "INHIXA": 146.14435753282967, "LANTUS": 2.0471236583816688, "LEVEMIR": 2.66835686005716, "METHOTREXATE": 0.9883720545151248, "NOVORAPID": 3.1662529253667806, "PANTOPRAZOLE": 6.654799147621504, "PEGASYS": 0.2771862773465499, "PROPRANOLOL": 8.163264125890032, "ROACTEMRA": 7.480144202681702, "SIMPONI": 30.7605341671301, "STELARA": 11.54973229467302, "TOUJEO": 6.434243098805027, "TREMFYA": 73.6126439571255, "XOLAIR": 6.233384332184372, "null": 2.0221115156032776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8059.json
index b3bd4a9546f..ed73704ccbf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8059.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8059.json
@@ -1 +1 @@
-{"null": 1.0215285781228296}
\ No newline at end of file
+{"null": 4.889930953678867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/806.json
index fb5bf4f7120..d89ea83e388 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/806.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/806.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 72.44399289206207, "ASPARAGINASE": 11.791158140462096, "BASILIXIMAB": 113.15181663826073, "BUDESONIDE": 10.203487494510412, "BUSULFAN": 147.88251810344386, "CARMUSTINE": 25.8132013532908, "CELLCEPT": 34.87374907063698, "CICLOSPORIN": 58.91817623696521, "CYTARABINE": 8.457186047866314, "ECULIZUMAB": 149.3936424243999, "JAKAVI": 4.5330797831799, "METHOTREXATE": 4.770657727589728, "MYCOPHENOLATE": 64.16217618913932, "RUXOLITINIB": 23.62533352555422, "SOLIRIS": 6.9306087829626986}
\ No newline at end of file
+{"COMIRNATY": 0.8193261329714234, "null": 1.0663960003559525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8060.json
index c79328b907a..3246e12cd35 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8060.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8060.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2659187257668223}
\ No newline at end of file
+{"BRIDION": 354.74815181638536, "DEXAMETHASONE": 31.095970666935216, "FENTANYL": 55.981404068569525, "null": 0.3380527281218915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8061.json
index 09c70b851ff..48c891a3679 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8061.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8061.json
@@ -1 +1 @@
-{"ANAKINRA": 3.936072121391616, "ANGIOX": 15.06689162095558, "AVANDAMET": 1.556650931966618, "AVANDIA": 1.4829463700611245, "AVASTIN": 1.5016334580715212, "BEVACIZUMAB": 1.2777311745693245, "CABOMETYX": 1.155198016357439, "CINRYZE": 2.483107490169305, "CLOPIDOGREL": 1.4573212476375983, "COVID19": 1.540832997390364, "DOXORUBICIN": 1.1381839548386663, "DULAGLUTIDE": 1.3647212725588471, "DUPIXENT": 1.08090296518573, "EFIENT": 1.0711043842395327, "ELIQUIS": 9.98676141062094, "ENOXAPARIN": 3.037490213944926, "ESBRIET": 1.2973083716140656, "EVISTA": 6.859674353407695, "EVRA": 3.1250812265411345, "FASLODEX": 1.0228962811071285, "FILGRASTIM": 1.439015130581502, "HEMLIBRA": 1.5110482538940266, "HIZENTRA": 2.854015766676838, "IBRANCE": 2.916409384188319, "ICLUSIG": 1.880091377636077, "INLYTA": 2.1400664587322344, "INTEGRILIN": 10.43120476899411, "LANTUS": 1.0579796694482928, "LEVEMIR": 1.0655729506187692, "LIXIANA": 2.186727757315752, "MISOPROSTOL": 6.276124838980427, "NEULASTA": 1.3804187421330238, "NINLARO": 2.08882954836856, "NOVOSEVEN": 12.16081409048568, "NPLATE": 4.1292473083755565, "OCRELIZUMAB": 2.1192417828723364, "ONCASPAR": 1.7429635981684124, "PLAVIX": 2.866722261456152, "RAPAMUNE": 1.3575291588816247, "REVATIO": 1.4061146736597407, "REVLIMID": 5.235736846282176, "RINVOQ": 3.384953273007905, "RIVAROXABAN": 5.392012464658995, "RUCONEST": 6.541343816846738, "SOLIRIS": 2.2037143568700666, "SUTENT": 1.2026161545783456, "TAGRISSO": 1.6087327624786611, "TESTOSTERONE": 2.770689065908854, "THALIDOMIDE": 1.2047745836864625, "TOZINAMERAN": 2.6350367394032865, "TRELEGY": 1.314929872300295, "TREMFYA": 1.0054830812775144, "VAXZEVRIA": 1.7595000758268868, "VEKLURY": 1.3987612316298863, "VELTASSA": 2.3351573519179567, "VIAGRA": 1.184284528649743, "VOTRIENT": 1.7010213510626575, "XALKORI": 2.7876026998942804, "XARELTO": 3.617483521030592, "XELJANZ": 2.900543624967113}
\ No newline at end of file
+{"ARIPIPRAZOLE": 336.27209650344435}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8062.json
index d077998d9e6..65f51cb4332 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8062.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8062.json
@@ -1 +1 @@
-{"ANGIOX": 1411.7258483360908, "BRILIQUE": 25.49245771222767, "CLOPIDOGREL": 19.279328379438024, "COVID19": 1.0523224662103945, "EFIENT": 54.40024469405927, "ELIQUIS": 1.1190022725314066, "INTEGRILIN": 57.21520619148361, "NOVOSEVEN": 36.71735091326151, "OPSUMIT": 6.6578411475383925, "PLAVIX": 35.79999473605581, "null": 1.0135009775266293}
\ No newline at end of file
+{"ABILIFY": 3.761392548046301, "ARIPIPRAZOLE": 5.533513576032692, "BRINTELLIX": 21.19624265151812, "CHAMPIX": 34.82197659870145, "COMIRNATY": 0.1424794384394073, "CYMBALTA": 3.5125366127135917, "KEPPRA": 4.214075983465254, "LATUDA": 12.210437613776168, "PEGASYS": 1.4291626627540723, "VAXZEVRIA": 0.1228921355102982, "null": 1.806581035777036}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8063.json
index 4b664f2775d..7560ece2829 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8063.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8063.json
@@ -1 +1 @@
-{"VAXZEVRIA": 2.728329918163163}
\ No newline at end of file
+{"ARIPIPRAZOLE": 22.98327458530949, "OLANZAPINE": 30.97489053999608, "null": 2.039787118955732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8064.json
index af4f41f791e..c6580c23be3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8064.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8064.json
@@ -1 +1 @@
-{"COVID19": 2.1160238036492616, "VAXZEVRIA": 50.984197369119926}
\ No newline at end of file
+{"CARIPRAZINE": 3436.650574946053, "null": 0.4491125594149601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8065.json
index d3fb0ade623..ab9942bdc32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8065.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8065.json
@@ -1 +1 @@
-{"EYLEA": 36.69699436613178, "FORXIGA": 43.483268509844834, "NEXAVAR": 10.021200334572695}
\ No newline at end of file
+{"YESCARTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8066.json
index c77397e61d4..c3b66daa00f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8066.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8066.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 15.695086587954654, "ALIMTA": 1.783574744600472, "AVASTIN": 2.627833428447544, "AZATHIOPRINE": 8.000987943929552, "BARACLUDE": 17.811544225557494, "BASILIXIMAB": 30.361179545275668, "BETAFERON": 10.124776492912403, "BEVACIZUMAB": 4.171632426132098, "BORTEZOMIB": 16.775965057481343, "BUSILVEX": 42.7143209847935, "BUSULFAN": 59.23649296479554, "CARFILZOMIB": 86.20752151095459, "CELLCEPT": 18.18281222727173, "CICLOSPORIN": 32.49491132786436, "CYTARABINE": 1.3880859792394769, "DARZALEX": 2.99515742442458, "DEFITELIO": 51.15663056011521, "DEXAMETHASONE": 2.305742017448785, "DINUTUXIMAB": 63.43992733938562, "ECULIZUMAB": 112.3892235278637, "GANCICLOVIR": 57.91471253342652, "ICLUSIG": 2.9541735766336026, "JAKAVI": 2.0533983118261814, "KYPROLIS": 98.46651724580556, "LAMIVUDINE": 4.217252247993341, "MELPHALAN": 57.31363703392644, "METHOTREXATE": 2.901458598411097, "MYCOPHENOLATE": 11.557000540945156, "RAPAMUNE": 17.715762209385286, "SOLIRIS": 55.79067919032297, "SUNITINIB": 30.93138083052052, "SUTENT": 2.2883090351839863, "TACROLIMUS": 24.854055910318632, "THIOTEPA": 28.27481572516789, "VOTRIENT": 1.7466575589354014}
\ No newline at end of file
+{"null": 2.1690594457872248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8067.json
index 641e9603449..5244fde5d1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8067.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8067.json
@@ -1 +1 @@
-{"ELIQUIS": 6.0205948439706285, "NOVOSEVEN": 202.00877410635283, "TOZINAMERAN": 1.3331365222004952}
\ No newline at end of file
+{"null": 2.8540848479347187}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8068.json
index 74170c9f036..c7cf9b453c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8068.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8068.json
@@ -1 +1 @@
-{"ALIMTA": 2.457834580901952, "AVASTIN": 3.469261436832653, "BORTEZOMIB": 12.185058020817925, "BUSULFAN": 9.798962658381337, "CELLCEPT": 3.323645534606744, "CICLOSPORIN": 8.255537601194238, "CLOPIDOGREL": 11.538927724944218, "KYPROLIS": 29.521433685834456, "LEMTRADA": 4.93918847614319, "PEGASYS": 3.595159884021149, "PEGINTERFERON": 4.45445813904927, "PEGINTRON": 4.25788171645187, "PLAVIX": 68.76039314357067, "SOLIRIS": 3.3535379076915657, "SUTENT": 2.1413072259441828, "TICAGRELOR": 6.361380751466973, "ZOSTAVAX": 1.2068125214368215}
\ No newline at end of file
+{"DEXAMETHASONE": 6.216422228518317, "FENTANYL": 22.52338291879965, "null": 4.090784604153764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8069.json
index 9412a66ca85..e30cdee019b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8069.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8069.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0047945967306957, "COVID19": 4.888028137089519, "TOZINAMERAN": 3.1082828765687265}
\ No newline at end of file
+{"SUBOXONE": 55.03428367824255, "null": 1.119567934549201}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/807.json
index ab68bf6668e..007910ad67c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/807.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/807.json
@@ -1 +1 @@
-{"DABRAFENIB": 1004.5702561249988, "MEKINIST": 111.732402846743}
\ No newline at end of file
+{"ANORO": 334.82379520779006, "APIXABAN": 114.14688817586574, "AZATHIOPRINE": 46.01184857854105, "COMIRNATY": 0.1380386107729045, "PANTOPRAZOLE": 51.84427240868112, "null": 0.631578385183668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8070.json
index 734a1c792e1..8cfb3e6ff3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8070.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8070.json
@@ -1 +1 @@
-{"COMTAN": 256.7979562969939, "null": 1.545948712561764}
\ No newline at end of file
+{"VIGABATRIN": 2147.1499701144967, "null": 3.126511123007744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8071.json
index ea925d09ca1..7bf340a773d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8071.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8071.json
@@ -1 +1 @@
-{"ASPARAGINASE": 2467.4379959956373}
\ No newline at end of file
+{"AMIKACIN": 1321.3792121936094, "null": 1.122026655990208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8072.json
index 5841975ec60..7d59cbd8a9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8072.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8072.json
@@ -1 +1 @@
-{"null": 1.695933139054759}
\ No newline at end of file
+{"null": 3.876165964643629}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8073.json
index c9a74d5de03..6d426d0eaa7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8073.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8073.json
@@ -1 +1 @@
-{"AVAMYS": 2.527365830530212, "BYDUREON": 5.823697970544982, "BYETTA": 42.425484437229386, "CELLCEPT": 1.325335575639797, "COSENTYX": 1.5606271355246706, "ENBREL": 1.044961486818463, "EXFORGE": 2.604958340625363, "HUMALOG": 1.6384655155568046, "HUMIRA": 1.7243161824918942, "JANUMET": 5.522385934452648, "JANUVIA": 1.835491272299531, "LANTUS": 2.114894516299211, "LEMTRADA": 4.485956921005423, "MEKINIST": 4.020398599762232, "NEXAVAR": 13.379094114689812, "ROACTEMRA": 2.86594340249732, "SAXENDA": 10.415305713153726, "SIMPONI": 2.628129881169558, "STELARA": 5.294489618838656, "TRULICITY": 11.520853832466871, "VICTOZA": 15.583935307161669, "XOLAIR": 2.2299419951494794, "null": 2.2317902343306857}
\ No newline at end of file
+{"FENTANYL": 37.91394977242407, "SUBOXONE": 48.6696527338376, "null": 2.63063498446812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8074.json
index 61166867894..0a333d07d66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8074.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8074.json
@@ -1 +1 @@
-{"BYETTA": 40.7296587505901, "CICLOSPORIN": 20.150005591740904, "NEXAVAR": 93.56880461316815}
\ No newline at end of file
+{"null": 0.8839493325626656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8075.json
index 16626ad35a4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8075.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8075.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 1.7038069753574496, "ARAVA": 1.5295497570951453, "AVAMYS": 4.258936277735723, "AXITINIB": 4.205265780274622, "BYDUREON": 1.675826556273146, "BYETTA": 1.1981541033089098, "CABOMETYX": 6.274420198919708, "ELIQUIS": 1.7577553376084476, "ESOMEPRAZOLE": 3.087644340943386, "EXFORGE": 1.4429739584171697, "FAMPYRA": 1.4433546962627153, "FORSTEO": 1.1456470737050737, "HARVONI": 2.6469330240135944, "HUMALOG": 6.992386315099293, "INLYTA": 6.51713019786418, "INSULIN": 1.8238440159703424, "INTRONA": 3.335622607398148, "IPILIMUMAB": 4.45171356922315, "JANUMET": 1.0292668569696093, "JANUVIA": 1.4022705348020414, "KEYTRUDA": 11.239268356469314, "LANTUS": 1.7023783783653352, "LEMTRADA": 16.259927877650952, "OPDIVO": 13.751972503811968, "PEGASYS": 4.371569488329394, "PEGINTRON": 3.411711297197196, "PEMBROLIZUMAB": 1.326342896107632, "SAXENDA": 1.561291998425419, "SUTENT": 9.351179517078643, "TRULICITY": 1.1161903275390814, "VIAGRA": 1.0005394098138611, "VICTOZA": 1.961547793791326, "VOTRIENT": 1.4559942595383992, "XELJANZ": 1.7606405825143687, "YERVOY": 6.7735081084961655, "ZOSTAVAX": 4.533358829503437, "null": 1.137020829883953}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8076.json
index 09d8ce14753..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8076.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8076.json
@@ -1 +1 @@
-{"KEYTRUDA": 5.692708112050763, "LEMTRADA": 21.82213989680832, "LYRICA": 5.148057677538167, "PEGASYS": 9.533002508274675, "PEGINTRON": 3.3548828495788072, "SUTENT": 10.94891047790884, "VOTRIENT": 4.674602976227767, "null": 1.024301684342684}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8077.json
index e55030f73fe..7fdd9525118 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8077.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8077.json
@@ -1 +1 @@
-{"KEYTRUDA": 14.120365693186525}
\ No newline at end of file
+{"ATOSIBAN": 1996.5794647630812, "null": 0.5779442939459161}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8078.json
index c72e33071a2..798344088db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8078.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8078.json
@@ -1 +1 @@
-{"CABOMETYX": 19.111157908554137, "KEYTRUDA": 8.041315214246424, "LEMTRADA": 23.09919146269037, "PEGASYS": 4.458305022485583, "SUTENT": 3.547704337880089}
\ No newline at end of file
+{"null": 1.87083069145616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8079.json
index 725912ac477..153d190504e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8079.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8079.json
@@ -1 +1 @@
-{"ADEMPAS": 14.75452783090638, "BYDUREON": 14.754103062646951, "BYETTA": 19.895979414458694, "CYMBALTA": 1.1884937018699355, "FASLODEX": 3.3004081428988896, "FORSTEO": 2.67737949605418, "GARDASIL": 1.0551561928365782, "IBRANCE": 1.7201125059865872, "JANUMET": 2.8285726511150115, "JANUVIA": 4.105133675601592, "JARDIANCE": 1.7922109848213834, "LEMTRADA": 5.4845458589740215, "SAXENDA": 18.97454354213747, "STELARA": 1.4580995408604456, "TRULICITY": 5.935347573442068, "VICTOZA": 26.639622219158987, "XELJANZ": 1.59767842772333, "ZOSTAVAX": 6.5886007643980005}
\ No newline at end of file
+{"INVIRASE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/808.json
index c9e5900b6f1..9e1b6cfe3a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/808.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/808.json
@@ -1 +1 @@
-{"null": 2.5855824849966824}
\ No newline at end of file
+{"COMIRNATY": 0.6004533828998333, "null": 0.6202658482019537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8080.json
index 47bffb951e3..7f72359fe89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8080.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8080.json
@@ -1 +1 @@
-{"ARAVA": 9.98092848928448, "AVAMYS": 13.731338799572873, "BYETTA": 9.93728604066932, "TRULICITY": 20.47303134348697, "VICTOZA": 40.03917374379909}
\ No newline at end of file
+{"null": 3.002030144881118}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8081.json
index 8ad61ba62da..f70878dbeb3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8081.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8081.json
@@ -1 +1 @@
-{"JANUMET": 29.294801343146897}
\ No newline at end of file
+{"null": 3.623889711580525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8082.json
index bcef0347e9e..4302b5e69f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8082.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8082.json
@@ -1 +1 @@
-{"COMIRNATY": 2.6756148219467577, "COVID19": 1.488851646406305, "SPIKEVAX": 1.218456438137561, "TOZINAMERAN": 2.483859214895332}
\ No newline at end of file
+{"null": 3.3375875379764297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8083.json
index a6ae3c3abd3..14e35683fe6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8083.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8083.json
@@ -1 +1 @@
-{"LEMTRADA": 1034.1950151487952}
\ No newline at end of file
+{"ABILIFY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8084.json
index 4f89e40c3a3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8084.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8084.json
@@ -1 +1 @@
-{"AVAMYS": 12.103747226502794, "BYETTA": 9.939138463734446, "CICLOSPORIN": 7.759749728517889, "JANUMET": 12.683965879919292, "LEMTRADA": 20.33452135401629, "OPSUMIT": 7.010894529027608, "ZOSTAVAX": 4.378751058950307, "null": 1.0069456984671703}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8085.json
index c9b2304c8a2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8085.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8085.json
@@ -1 +1 @@
-{"AXITINIB": 18.15431951042947, "BAVENCIO": 37.2716292013344, "CABOMETYX": 9.30495728638366, "INLYTA": 9.683328444485342, "IPILIMUMAB": 70.05052279764486, "IRBESARTAN": 5.78630768753406, "KEYTRUDA": 39.6958368585039, "LEMTRADA": 16.653037045645465, "LENVIMA": 6.217118023287381, "NEXAVAR": 1.240490381947311, "NIVOLUMAB": 22.22660525458709, "OPDIVO": 65.88600664414933, "PACLITAXEL": 7.414635514765443, "PEGASYS": 5.011843303437852, "PEGINTERFERON": 3.3266136747177044, "PEGINTRON": 6.9752149101148815, "PEMBROLIZUMAB": 18.04392353236316, "SUTENT": 1.1079902385693274, "TASIGNA": 1.7851419875294068, "YERVOY": 6.955764566201648}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8086.json
index 25e05d1386c..5c9dbd1710d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8086.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8086.json
@@ -1 +1 @@
-{"COMIRNATY": 2.185505935000232, "PEGASYS": 5.4604569705428805, "VAXZEVRIA": 1.3768422306647596}
\ No newline at end of file
+{"null": 1.8431777657473207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8087.json
index deb3ee0871d..1d979d302bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8087.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8087.json
@@ -1 +1 @@
-{"COMIRNATY": 3.193878693232928, "KEYTRUDA": 2.6349511871933253, "LEMTRADA": 12.853466586254806, "OPDIVO": 7.0407337600354944, "PEGASYS": 1.6498152514320945, "SPIKEVAX": 2.0226912975854536, "TOZINAMERAN": 5.158215641936212, "VAXZEVRIA": 1.757950429726111}
\ No newline at end of file
+{"null": 3.015891500848607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8088.json
index 96fadb0131c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8088.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8088.json
@@ -1 +1 @@
-{"FENTANYL": 4.652714006793215, "HYDROCORTISONE": 21.834880983549144, "IPILIMUMAB": 16.00775582564924, "KEYTRUDA": 9.139962402598456, "OPDIVO": 12.941417456050493, "null": 1.7179158966891537}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8089.json
index 7181dd91e6a..2ff399ee7c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8089.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8089.json
@@ -1 +1 @@
-{"null": 1.1878667024099252}
\ No newline at end of file
+{"null": 1.9659990130617704}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/809.json
index 5189de0c329..ea5024ec46a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/809.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/809.json
@@ -1 +1 @@
-{"null": 1.1017941805452511}
\ No newline at end of file
+{"COMIRNATY": 0.8242080887848695, "COSENTYX": 6.424361254158723, "null": 0.965783228736377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8090.json
index ffab1c51d74..815c3fd2bb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8090.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8090.json
@@ -1 +1 @@
-{"ARAVA": 1.2111101712645185, "ARIPIPRAZOLE": 69.84664286368881, "LEMTRADA": 55.71555832429561, "SUTENT": 5.489121593932908, "null": 1.188958084509613}
\ No newline at end of file
+{"null": 2.457594580105288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8091.json
index 0db7cce5477..e6bb33588b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8091.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8091.json
@@ -1 +1 @@
-{"LEMTRADA": 302.5200800878616}
\ No newline at end of file
+{"FENTANYL": 26.80693497616252, "LEVETIRACETAM": 19.13978505224685, "null": 3.628822878344191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8092.json
index ee2d9b5bb9a..4110c4f6132 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8092.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8092.json
@@ -1 +1 @@
-{"KEYTRUDA": 5.201735905959504, "LEMTRADA": 57.15881881817646, "null": 2.504065261972996}
\ No newline at end of file
+{"ABILIFY": 18.536098205789894, "BUPRENORPHINE": 14.080211529049611, "CYMBALTA": 1.208461987100628, "DEXAMETHASONE": 6.004664490939714, "KEPPRA": 4.433673964514407, "LANTUS": 1.245044167331718, "OLANZAPINE": 2.866774004028092, "SUBOXONE": 10.414364546775122, "ZYPREXA": 2.714470591450501, "null": 3.044423000365741}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8093.json
index 3752224dbad..21f0f243bd3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8093.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8093.json
@@ -1 +1 @@
-{"KEYTRUDA": 6.18934622980978, "LEMTRADA": 63.994883888, "null": 2.4888548247948585}
\ No newline at end of file
+{"ABILIFY": 4.267652956475717, "ATOSIBAN": 108.29782339958244, "BUDESONIDE": 1.6191348770666372, "BUPIVACAINE": 9.994869599195711, "BUPRENORPHINE": 3.0891076639240134, "CYMBALTA": 1.981825377503245, "DEXAMETHASONE": 9.652775343277789, "FENTANYL": 4.424444348814309, "INSULATARD": 46.40005896119211, "KEPPRA": 7.407987979831586, "LANTUS": 1.7916372751999092, "LEVEMIR": 6.965583677683898, "LEVETIRACETAM": 3.9778226864152417, "OLANZAPINE": 1.9677046661015816, "SUBOXONE": 10.154045924692598, "ZYPREXA": 4.484552222197485, "null": 2.4394414283882275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8094.json
index 66568c279b2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8094.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8094.json
@@ -1 +1 @@
-{"LEMTRADA": 71.32546412355751, "PEGASYS": 3.674212625672781, "null": 2.1099780843773632}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8095.json
index 40960616367..789e1ebfa6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8095.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8095.json
@@ -1 +1 @@
-{"ATRIPLA": 21.433211205973333, "EVENITY": 9.020705761638062, "EVISTA": 6.8662793905212345, "EXFORGE": 3.923154031353697, "FORSTEO": 10.303883257081171, "HEPSERA": 18.285661805768235, "HUMALOG": 1.7433562393698514, "LANTUS": 1.687488193048759, "SIMPONI": 1.3571408548665262, "SPINRAZA": 13.395104867026284, "STELARA": 1.3225200821677772, "STRIBILD": 10.712464721935309, "SUBOXONE": 3.257820204701702, "TRUVADA": 16.57487096589126, "VIREAD": 6.192673703728704, "XELJANZ": 2.723597235907611}
\ No newline at end of file
+{"null": 3.9797890078652833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8096.json
index 958942651d2..8463c04b11b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8096.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8096.json
@@ -1 +1 @@
-{"null": 1.4952445862083286}
\ No newline at end of file
+{"LACOSAMIDE": 96.87803389142852, "SUBOXONE": 20.164969480864585, "null": 4.790631414738462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8097.json
index f5c43ae8af2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8097.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8097.json
@@ -1 +1 @@
-{"ABILIFY": 6.4360146466369, "BRINTELLIX": 7.744349881724241, "CYMBALTA": 1.992148315983256, "GARDASIL": 6.941868560183478, "KAFTRIO": 6.391404483687637, "KEPPRA": 2.48019282059977, "LATUDA": 6.425829670251649, "OLANZAPINE": 1.2705380750225328, "ZYPREXA": 1.8286863075062307, "null": 3.3677228096086265}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8098.json
index c57232a4ba2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8098.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8098.json
@@ -1 +1 @@
-{"null": 1.0073536249268118}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8099.json
index 63a4516c789..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8099.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8099.json
@@ -1 +1 @@
-{"null": 1.07066998585515}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/81.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/81.json
index 1ef076dc31d..949cb8d6a91 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/81.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/81.json
@@ -1 +1 @@
-{"ABASAGLAR": 181.5460973674148, "COSENTYX": 2.328176361134584, "FORSTEO": 6.462448160298963, "HUMALOG": 57.48463044537778, "INSULIN": 19.67728845955613, "MOVYMIA": 331.37723142486703, "PLEGRIDY": 26.6908208958039, "ROTATEQ": 48.418433487119, "RUBRACA": 15.58824161343866, "SIMPONI": 3.5629666945834844, "TRULICITY": 43.03843712659554}
\ No newline at end of file
+{"ASPARAGINASE": 430.01279390507, "null": 0.253352566054941}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/810.json
index dbb34b2beb2..05f02b08dcb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/810.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/810.json
@@ -1 +1 @@
-{"CICLOSPORIN": 100.68383597702528}
\ No newline at end of file
+{"ADALIMUMAB": 3.3895704949607395, "AIMOVIG": 3.177340796473604, "ARAVA": 1.1803817619739032, "CELECOXIB": 9.359985871974756, "CICLOSPORIN": 2.333602606253837, "CIMZIA": 0.9414613520198056, "COMIRNATY": 0.3036950733672057, "COSENTYX": 1.427970856741399, "CYMBALTA": 0.7540711808034475, "DEXAMETHASONE": 2.809112172781676, "EMPAGLIFLOZIN": 20.817546563769028, "ENBREL": 2.528105480790253, "GARDASIL": 3.7864937317592338, "PEGASYS": 1.1205227906440145, "PEGINTRON": 1.7871334190794834, "SPIKEVAX": 0.1614926480810342, "STELARA": 2.330010660957288, "TOZINAMERAN": 0.6951270898361098, "VAXZEVRIA": 0.0813665695463758, "XOLAIR": 2.757847378933025, "null": 1.8557434887788156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8100.json
index 427a6d01930..d127a37fb95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8100.json
@@ -1 +1 @@
-{"null": 1.1751565399393764}
\ No newline at end of file
+{"null": 2.487321148740122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8101.json
index b2555db9615..8e441f8ad68 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8101.json
@@ -1 +1 @@
-{"APIDRA": 28.121610736862504, "DELAMANID": 111.79143234276958}
\ No newline at end of file
+{"DEXAMETHASONE": 28.454403942383788, "null": 2.23743296536873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8102.json
index cc2b1cb5355..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8102.json
@@ -1 +1 @@
-{"APIDRA": 16.430660482397638, "BIKTARVY": 56.24260744027168, "COSENTYX": 21.988833235846776, "ZOSTAVAX": 4.6041639707257564, "ZYPREXA": 6.813225132136809}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8103.json
index 25440497008..86dbe84c523 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8103.json
@@ -1 +1 @@
-{"STELARA": 15.929506415333057}
\ No newline at end of file
+{"null": 5.591518536765223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8104.json
index 49a42f1cbcd..5dd79997a07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8104.json
@@ -1 +1 @@
-{"AIMOVIG": 2.242797215287148, "AJOVY": 5.60158434147851, "AMIKACIN": 2.754651579354128, "APROVEL": 1.898881331005434, "APTIVUS": 3.683780988840986, "BRINTELLIX": 2.011666935494608, "CHAMPIX": 1.0757640677670626, "COAPROVEL": 2.1187803314035234, "COMIRNATY": 2.4262952268732096, "COVID19": 2.1464201427422176, "CYMBALTA": 4.130101106715045, "EXFORGE": 1.901863734809276, "GALAFOLD": 1.2964794033665794, "HYDROCHLOROTHIAZIDE": 1.307342314078922, "INTELENCE": 1.5019489980312375, "IRBESARTAN": 1.045236705343875, "KAFTRIO": 1.5216404764672455, "MICARDIS": 1.1396588102952927, "OCRELIZUMAB": 1.1707104515156168, "RANEXA": 3.5800039582897085, "SPIKEVAX": 2.052292351488166, "TELMISARTAN": 1.1914948101668212, "TIGECYCLINE": 3.817653691905613, "TOBRAMYCIN": 3.927624229707052, "TOZINAMERAN": 2.853490623374106, "TWINRIX": 1.0382394861494724, "VAXZEVRIA": 1.523255373678721, "VIAGRA": 1.6611821614277065, "VIMPAT": 1.1626164690826957}
\ No newline at end of file
+{"AFINITOR": 2.684774116894966, "ATEZOLIZUMAB": 20.44049801996021, "AVASTIN": 3.64973605911209, "BEVACIZUMAB": 2.3676680354595434, "CELLCEPT": 1.2058749261971615, "CHAMPIX": 0.6229783800171352, "CICLOSPORIN": 1.3987587143716775, "CIMZIA": 0.7961899731214017, "CLOPIDOGREL": 1.9146631931526408, "COMIRNATY": 0.1988450928106617, "COSENTYX": 1.4946627592490809, "CYTARABINE": 2.602491106837406, "DABRAFENIB": 9.161247639507623, "DEXAMETHASONE": 1.558285503495102, "ELIQUIS": 2.679240879877634, "EXFORGE": 4.554524020868539, "FASLODEX": 1.635209852144748, "FORSTEO": 2.8417359295310503, "HERCEPTIN": 3.380014602364869, "HUMALOG": 1.091228995129089, "IBRANCE": 1.366714207375786, "JAKAVI": 2.478075722248186, "JARDIANCE": 0.631877197260105, "KEPPRA": 1.125980730440712, "KEYTRUDA": 0.8636070916311633, "KISQALI": 4.562013437372067, "LANTUS": 2.5713935091488533, "LYNPARZA": 5.273056498402237, "LYRICA": 1.271879424645422, "MEKINIST": 6.161463275336881, "METHOTREXATE": 1.631208418641583, "NEXAVAR": 0.8912546425735188, "OPDIVO": 1.887561343073388, "PEGASYS": 0.9245317054440796, "ROACTEMRA": 5.299096410060584, "RUBRACA": 5.61590484322116, "SIMPONI": 4.084357883263987, "SPIKEVAX": 0.074578979429217, "STELARA": 1.594808341992942, "SUTENT": 0.9272248303521436, "TOZINAMERAN": 0.4250971532125996, "VAXZEVRIA": 0.0586903210245769, "VOTRIENT": 5.259648947893268, "XELJANZ": 2.512431573449152, "XOLAIR": 1.2751379508910785, "XTANDI": 2.78309094623456, "YERVOY": 5.372987939217346, "ZELBORAF": 32.394735538409606, "null": 1.1550390247095534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8105.json
index ef3fb3f17de..8cdd76b6c60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8105.json
@@ -1 +1 @@
-{"VAXZEVRIA": 1.8565676827621609, "null": 1.4478736674516994}
\ No newline at end of file
+{"ABATACEPT": 0.2001594050947353, "ADALIMUMAB": 0.0913120475710987, "AERIUS": 0.847977459936094, "AFINITOR": 0.7884970134028378, "AIMOVIG": 0.7036678877022805, "ANORO": 2.0337387666960214, "APIDRA": 0.7279219072624241, "ARANESP": 1.6794468414318184, "ARAVA": 1.246839923749704, "ATRIPLA": 0.0560191816722364, "AUBAGIO": 1.1180377426936452, "AVANDIA": 0.1363781515744257, "AVASTIN": 0.7072456118512693, "AZATHIOPRINE": 0.3227568239152503, "BARACLUDE": 2.8650002289867538, "BENLYSTA": 0.7521999639817751, "BEVACIZUMAB": 0.3178063150683802, "BIKTARVY": 1.4953613901972729, "BOSULIF": 1.0108312428223285, "BRAFTOVI": 0.7423983306422131, "BRILIQUE": 0.3831159199050261, "BUDESONIDE": 0.393273691791988, "BUPRENORPHINE": 0.2534956510554641, "BYDUREON": 0.7338069250062168, "BYETTA": 0.5442626690292128, "CABOMETYX": 0.4797664252634623, "CELECOXIB": 0.8350434656560806, "CELLCEPT": 0.9097376592507208, "CHAMPIX": 0.4281751583873465, "CHEMOTHERAPY": 10.777709124109515, "CICLOSPORIN": 0.7091627947945996, "CIMZIA": 0.6957051998208037, "CLOPIDOGREL": 0.1603270703356017, "COMIRNATY": 0.0571355936889171, "COSENTYX": 0.7098841380444154, "CRIZOTINIB": 7.980252722632817, "CYMBALTA": 0.5046377011330252, "DESCOVY": 1.9794135132446724, "DEXAMETHASONE": 0.2168871782833121, "DULAGLUTIDE": 2.397209023425353, "ELIQUIS": 5.238365577048839, "EMEND": 1.386161433737718, "ENBREL": 1.8863414971756465, "ENTRESTO": 0.9247185386899276, "ENTYVIO": 0.5185691628614021, "ERLEADA": 2.164180853164125, "ESBRIET": 1.913205450910777, "EVENITY": 1.4909852794809386, "EVISTA": 1.1200682979240486, "EXFORGE": 1.7085721144746286, "EXJADE": 0.4426224449562233, "FAMPYRA": 1.3271812338868536, "FASENRA": 0.9403845609691988, "FASLODEX": 2.303225593522336, "FENTANYL": 0.1600313138905586, "FILGRASTIM": 1.8439442089264768, "FIRDAPSE": 1.6228986027866543, "FORSTEO": 1.1764806924826294, "FORXIGA": 0.4031447367918419, "FULVESTRANT": 0.8638051064894844, "GARDASIL": 0.199509935116606, "HARVONI": 1.3629579402222458, "HERCEPTIN": 0.8638599951271904, "HIZENTRA": 1.7879228000271024, "HUMALOG": 2.7014536227219765, "HUMIRA": 0.4504495796751045, "HYDROCORTISONE": 0.4151004022342571, "IBRANCE": 0.947106443813076, "INCRUSE": 3.883804197451501, "INLYTA": 2.5454735328346323, "INSULIN": 1.3334227470434314, "IRESSA": 0.4968630366703372, "ISENTRESS": 2.016526566631625, "JAKAVI": 0.7304631292050785, "JANUMET": 1.0573858606895783, "JANUVIA": 2.282813123309375, "JARDIANCE": 3.2954986494541294, "KAFTRIO": 0.951259540401216, "KEPPRA": 0.3535825856435073, "KEYTRUDA": 0.5680585289781891, "KISQALI": 0.7756828764715296, "LANTUS": 3.128526128821905, "LATUDA": 0.7768365439592609, "LEMTRADA": 0.5797802331546678, "LEVEMIR": 2.439254043120021, "LIBTAYO": 4.139028660434776, "LYNPARZA": 1.2124545120472934, "LYRICA": 1.5527270238043749, "MEKINIST": 1.4150353923298105, "MEPOLIZUMAB": 1.5691866290368477, "METHOTREXATE": 0.6659504244954046, "MICARDIS": 0.5644636195794244, "MIRCERA": 1.596786544543323, "NEULASTA": 2.303041986971433, "NEXAVAR": 0.1647726248604051, "NOT": 1.1652819464706885, "NOVORAPID": 0.2863641583880978, "NPLATE": 1.0434021845639485, "NUCALA": 0.5304318602714623, "OCALIVA": 1.2534797184440605, "OFEV": 1.3291249443092183, "OMALIZUMAB": 0.2667629081005771, "OPDIVO": 0.2563449291128132, "OPSUMIT": 1.0748112223416666, "PASIREOTIDE": 21.03353439972257, "PEGASYS": 0.1754063027958685, "PEGINTRON": 0.3267598854953517, "PLAVIX": 0.5033591636491515, "PLEGRIDY": 0.5386157101926067, "PLUVICTO": 6.092625850982343, "RAPAMUNE": 4.099530097592688, "REVATIO": 2.3326324008254167, "RINVOQ": 2.173143974391931, "ROACTEMRA": 0.7285249632658152, "SAXENDA": 0.3943539355286189, "SHINGRIX": 0.7616335961197563, "SIMPONI": 2.2495269826113806, "SOLIRIS": 0.8708897325443931, "SOVALDI": 2.3829166882263846, "SPIKEVAX": 0.053624190280689, "SPRYCEL": 0.9398816698270744, "STELARA": 1.2860245080319963, "STIVARGA": 0.343137373830368, "SUBOXONE": 0.7385927109568187, "SUTENT": 2.3728855243674007, "TAGRISSO": 0.5446705236541567, "TASIGNA": 0.3659072804645981, "TORISEL": 4.114377887002928, "TOUJEO": 2.424678179938528, "TOVIAZ": 2.416904902567219, "TOZINAMERAN": 0.2332203949861429, "TRACLEER": 0.7248730703172902, "TRELEGY": 6.840172200504258, "TREMFYA": 1.916995909424331, "TRULICITY": 3.5067715983238488, "TRUVADA": 0.1292022883593584, "VAXZEVRIA": 0.0303761042426636, "VELTASSA": 1.4529844170581514, "VEMLIDY": 4.206086757849832, "VFEND": 2.626276122262664, "VIAGRA": 7.365277405295108, "VICTOZA": 2.0165969064812894, "VOTRIENT": 4.357770247904095, "XALKORI": 6.995653352001748, "XELJANZ": 3.899584161136834, "XOLAIR": 1.6317722855399732, "XTANDI": 1.5402588534371842, "ZELBORAF": 1.6280205849121778, "ZOSTAVAX": 0.8273464526668179, "ZYPREXA": 0.3309184397957208, "null": 2.5740127931234102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8106.json
index 9982dbf3e51..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8106.json
@@ -1 +1 @@
-{"ZOSTAVAX": 15.364687387318444, "null": 2.7522659942779586}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8107.json
index 4b9b477fa6a..0b98f445811 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8107.json
@@ -1 +1 @@
-{"OLANZAPINE": 112.26635843984668}
\ No newline at end of file
+{"ABACAVIR": 0.3589530234085016, "ABRAXANE": 12.139220611551323, "ADCETRIS": 4.999396475545985, "AFINITOR": 14.765506789818623, "ALECTINIB": 20.30908897295376, "ALIMTA": 10.840530994796836, "ARIPIPRAZOLE": 1.5888861156699097, "ASPARAGINASE": 0.7069583918204623, "AVASTIN": 4.675266832018198, "AVELUMAB": 34.31551260473867, "AXITINIB": 23.472344595380733, "BAVENCIO": 23.7186344047527, "BEVACIZUMAB": 13.495650407854704, "BINIMETINIB": 8.657878374988124, "BLINATUMOMAB": 3.416279302240109, "BLINCYTO": 5.854621454597867, "BORTEZOMIB": 1.5214224364899769, "BOSULIF": 13.477764058775024, "BOSUTINIB": 7.607856672508886, "BRAFTOVI": 41.482383360703295, "BUSULFAN": 1.1144077339201248, "CABOMETYX": 1.4773435863061126, "CAELYX": 6.484491072544475, "CANCIDAS": 3.3264228941321394, "CAPECITABINE": 4.2088649848834345, "CAPRELSA": 3.644448726396821, "CASPOFUNGIN": 1.0528242328061272, "CIALIS": 3.9870605567468895, "CICLOSPORIN": 0.2919596292936792, "CLADRIBINE": 2.036846009373656, "CLOFARABINE": 3.410873043513219, "CLOPIDOGREL": 0.1060884527822874, "COMIRNATY": 0.0228467091619372, "CRIZOTINIB": 13.687230092176735, "CYTARABINE": 2.495175503653735, "DABRAFENIB": 2.573619239728883, "DENOSUMAB": 10.567728316547894, "DEXAMETHASONE": 1.375063531570282, "DINUTUXIMAB": 20.642783159820247, "DOCETAXEL": 3.9198804299140657, "DOXORUBICIN": 5.393891934457058, "ELIQUIS": 0.1152954565384032, "ERBITUX": 3.1683264039448917, "ERIBULIN": 9.50096419372044, "ERLOTINIB": 36.83248526103096, "EVEROLIMUS": 8.151092738862795, "EXJADE": 2.3131460758941658, "FASLODEX": 18.54235192038265, "FENTANYL": 0.2073868873817808, "FILGRASTIM": 4.055131988845357, "FULVESTRANT": 27.257677901187712, "GLIVEC": 4.218123562435118, "HERCEPTIN": 0.6932112384159967, "IBRANCE": 68.2555624268292, "ICLUSIG": 20.95868142075205, "IMATINIB": 4.893207978952876, "INFLIXIMAB": 1.145615915078113, "INLYTA": 46.8356640027241, "IPILIMUMAB": 0.6498198824902027, "IRESSA": 2.999499742324912, "IRINOTECAN": 2.9750941441932506, "KEPPRA": 0.1210305898806104, "KEYTRUDA": 0.2771714148209762, "LENALIDOMIDE": 4.269274301021267, "LEVOFLOXACIN": 0.1774722288314034, "LONSURF": 0.8024149348543921, "LUTATHERA": 6.787175024997808, "LUTETIUM": 6.259368173684158, "LYNPARZA": 1.1428229482519563, "MEKINIST": 1.3335778908025056, "METHOTREXATE": 0.2637264515133721, "NEULASTA": 1.3602529881691958, "NEXAVAR": 1.441538604571545, "NOT": 0.7710321340322678, "PACLITAXEL": 4.04961524736345, "PALBOCICLIB": 32.93367121164228, "PAZOPANIB": 2.3883253303420777, "PEMBROLIZUMAB": 0.8087733244955175, "PEMETREXED": 5.898010270704583, "RITUXIMAB": 1.2512538250181302, "RUBRACA": 1.2060700226252912, "SORAFENIB": 3.452534897166229, "STIVARGA": 1.2204328194564389, "SUNITINIB": 6.036755141801905, "SUTENT": 34.323537058531734, "TAGRISSO": 2.3573911721813654, "TASIGNA": 1.5417222300277862, "TEMODAL": 3.231750117357893, "TEMOZOLOMIDE": 10.827016044707758, "TOPOTECAN": 4.272878503168244, "TORISEL": 14.6171425037178, "TOZINAMERAN": 0.0307667946124073, "VFEND": 0.4637600692434342, "VIAGRA": 0.9110784071006224, "VOTRIENT": 1.9937658772580011, "XALKORI": 55.10796811966359, "XELJANZ": 0.1066778128638065, "XELODA": 1.6078287987139948, "XOFIGO": 1.6204180319581651, "ZELBORAF": 1.7338759408160316, "null": 0.2244630940985567}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8108.json
index 8665079ac50..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8108.json
@@ -1 +1 @@
-{"null": 8.447912192520246}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8109.json
index d3fd0c59b2e..6bc964dcf03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8109.json
@@ -1 +1 @@
-{"CHAMPIX": 122.80309758044258, "null": 2.327324288687125}
\ No newline at end of file
+{"null": 0.4211122573965482}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/811.json
index f0d957e0a03..36c35a8545a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/811.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/811.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9032479362966503, "COVID19": 3.08879576801702, "SPIKEVAX": 7.613017381293346, "TOZINAMERAN": 1.8228444223570972}
\ No newline at end of file
+{"OLANZAPINE": 32.25425948006013, "null": 0.5417393194743858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8110.json
index 966ea24d301..8b9b739ec43 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8110.json
@@ -1 +1 @@
-{"CHAMPIX": 373.64173975128256}
\ No newline at end of file
+{"AFINITOR": 2.850839766979131, "ASPARAGINASE": 15.05486522354311, "BRAFTOVI": 9.368481757081865, "CICLOSPORIN": 2.967673890176744, "COMIRNATY": 0.0706414960559961, "CYTARABINE": 18.0973582551348, "DEXAMETHASONE": 2.7370125769236893, "DOCETAXEL": 16.69695529630055, "FASLODEX": 12.949196903280855, "GLIVEC": 89.01957280268876, "IBRANCE": 15.037202631584377, "IMATINIB": 30.74688762020015, "SOMATROPIN": 93.530186464796, "SUTENT": 4.9972679489896725, "VFEND": 5.898440360400695, "XELJANZ": 1.762193968756014, "null": 0.6979541046787743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8111.json
index a172c64ba39..795072fd7ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8111.json
@@ -1 +1 @@
-{"APIDRA": 7.771512294073851, "AVANDIA": 2.205213782983147, "EMPAGLIFLOZIN": 26.86507434808359, "ENBREL": 2.681468550120289, "FORXIGA": 25.99462519736602, "HUMALOG": 7.326867014125879, "INSULIN": 5.3542382786218745, "INVOKANA": 504.1782489129577, "JANUMET": 4.371103465973167, "JANUVIA": 3.50881997514175, "JARDIANCE": 36.553059754494726, "LANTUS": 22.55648727604941, "LEVEMIR": 19.544256783098888, "STRIBILD": 2.4233715198134385, "VELTASSA": 22.579026283911684}
\ No newline at end of file
+{"CELLCEPT": 9.42283223687556, "CICLOSPORIN": 10.031707813520525, "COMIRNATY": 0.1629108223868106, "COSENTYX": 5.274391423006767, "DEXAMETHASONE": 6.582782506507619, "ENBREL": 9.47135129732481, "JAKAVI": 15.644661437916223, "ZOSTAVAX": 5.878798675451512, "null": 0.7054733675678964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8112.json
index e1f5ade6b5f..ef80608db89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8112.json
@@ -1 +1 @@
-{"SIMPONI": 22.811019738467746}
\ No newline at end of file
+{"METHOTREXATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8113.json
index f476eeac983..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8113.json
@@ -1 +1 @@
-{"null": 4.272651510480063}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8114.json
index 81694b6253c..a923d1474db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8114.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6902136768989269}
\ No newline at end of file
+{"EXFORGE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8115.json
index 7de7fa7b481..8c7201632c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8115.json
@@ -1 +1 @@
-{"CYMBALTA": 2.072344799307741, "GARDASIL": 3.2083603613432325, "KEPPRA": 6.8674473329428585, "LANTUS": 1.603239730346818, "OLANZAPINE": 3.2966425279324736, "null": 2.5666048382896545}
\ No newline at end of file
+{"BEOVU": 73.56496946099988, "COMIRNATY": 0.2777946034300706, "ELIQUIS": 4.134589110954746, "EYLEA": 129.69501153697115, "HUMALOG": 3.593758798965881, "VAXZEVRIA": 0.2258772172277834, "null": 0.9746005756610212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8116.json
index f0be45a9da6..af5f353c7c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8116.json
@@ -1 +1 @@
-{"IBRANCE": 2.3188982405938505, "NEXAVAR": 2.9083840566205024, "PEGASYS": 1.136508866430452, "SUTENT": 6.136611864544869, "TRELEGY": 5.707818731135406, "null": 1.3730950703114109}
\ No newline at end of file
+{"AIMOVIG": 448.09158576660377, "ERENUMAB": 1602.3203926596684, "null": 0.0935584597217699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8117.json
index 7bb7a98c9e7..c6eff9887c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8117.json
@@ -1 +1 @@
-{"CHAMPIX": 3.4152138190619423, "COSENTYX": 1.602228757857118, "FORSTEO": 2.8366328577809226, "PEGASYS": 1.0163291204201914, "TRELEGY": 5.263065139038861, "null": 2.1275600443488623}
\ No newline at end of file
+{"ACLIDINIUM": 38.63190251255492, "APIXABAN": 144.94766081879092, "ATRIPLA": 3.198416145675873, "CELLCEPT": 3.715300834994944, "CICLOSPORIN": 12.469734920694206, "ELIQUIS": 4.946373498660724, "INLYTA": 24.85979703431633, "JARDIANCE": 2.204902989355615, "LANTUS": 1.4235777592506595, "MYCOPHENOLATE": 16.403682988713747, "SUTENT": 2.8421971137719275, "TRUVADA": 1.143361622443084, "VOTRIENT": 8.576910030566427, "null": 0.2753900594122411}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8118.json
index b7b5b61afed..d34e913af16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8118.json
@@ -1 +1 @@
-{"PEGASYS": 1.7431831276500878, "PEGINTRON": 1.4795649087154292, "SUTENT": 1.890091877453708, "null": 5.391392431656931}
\ No newline at end of file
+{"AFINITOR": 52.048201006349096, "COMIRNATY": 0.3488512950362415, "null": 0.3631644855852556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8119.json
index 013adcaf42b..1e5c35e169c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8119.json
@@ -1 +1 @@
-{"AFINITOR": 1.1062582311669455, "COSENTYX": 1.0178715838292396, "EFAVIRENZ": 5.459728999310282, "ENTRESTO": 1.1219055877060895, "FORSTEO": 1.5293888110265892, "INLYTA": 2.858204674806904, "NEXAVAR": 1.0815867245796933, "SUTENT": 7.15119471608903, "TRELEGY": 1.476454367504208, "VOTRIENT": 2.6302390230282424, "null": 2.538590796726074}
\ No newline at end of file
+{"ABACAVIR": 1.8945187359821, "ALIMTA": 9.359551566284056, "AMINOSALICYLIC": 5.984178775828358, "ATRIPLA": 0.5992113399741112, "AXITINIB": 17.28791045060176, "BENLYSTA": 9.944140421621668, "CICLOSPORIN": 1.5356860192895938, "CLOPIDOGREL": 1.1902151724289576, "COMIRNATY": 0.3932873815639587, "HEMLIBRA": 22.588099575935384, "INLYTA": 3.373467730099228, "IPILIMUMAB": 23.81096487403195, "JARDIANCE": 2.42984041896432, "KEYTRUDA": 33.226557355843035, "OPDIVO": 13.70680988880464, "PEGINTRON": 1.1849726548390116, "PEMBROLIZUMAB": 31.09310465190787, "SPIKEVAX": 0.2328112154430392, "SUTENT": 1.0300083253533048, "TOZINAMERAN": 0.2467663270683988, "TRUVADA": 1.061277287807371, "null": 0.6766486909994457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/812.json
index 167a0f7f2a4..57cb9888a9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/812.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/812.json
@@ -1 +1 @@
-{"AZACITIDINE": 97.91668952419596, "ENTYVIO": 102.88609375192576}
\ No newline at end of file
+{"COMIRNATY": 0.4561108480268974, "STELARA": 8.197757393027254, "VAXZEVRIA": 0.4822557659870028, "null": 1.4597647953818416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8120.json
index ee6e8f4c98c..c717ff2e75c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8120.json
@@ -1 +1 @@
-{"ABATACEPT": 1.0420105374722266, "ADALIMUMAB": 1.084160228413457, "AFINITOR": 1.2679929541326072, "CHAMPIX": 1.6151393054244985, "IBRANCE": 2.721941127507206, "INLYTA": 4.118691375170656, "LEVETIRACETAM": 2.2281372618864235, "PEGASYS": 2.371113596964113, "PEGINTRON": 2.5842445354635366, "SUTENT": 6.277994334515668, "TOZINAMERAN": 1.598198927066709, "XELJANZ": 1.128791097366877, "XOLAIR": 2.40085035171356, "ZYPREXA": 1.2837152816997954, "null": 1.89543225090665}
\ No newline at end of file
+{"null": 2.641606896739538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8121.json
index aca026847d7..76ac2ccadb2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8121.json
@@ -1 +1 @@
-{"CHAMPIX": 3.245085857609662, "SUTENT": 4.058043896172285, "TOZINAMERAN": 1.3892470355811597, "null": 1.544454173366456}
\ No newline at end of file
+{"null": 1.5101103453775089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8122.json
index 2feacb93946..e5574f02051 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8122.json
@@ -1 +1 @@
-{"null": 1.8361228280589683}
\ No newline at end of file
+{"MIMPARA": 80.32732908656111, "null": 2.564017819716931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8123.json
index dac80822718..02b171aad13 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8123.json
@@ -1 +1 @@
-{"CHAMPIX": 2.6545457502267094, "FORSTEO": 2.8831152868919405, "PEGASYS": 2.197327208547188, "SUTENT": 6.330584823094933, "null": 2.5098855509792592}
\ No newline at end of file
+{"ATRIPLA": 13.7850316781125, "SUTENT": 1.348566619893501, "TRUVADA": 8.653046718866833, "null": 0.667217688641151}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8124.json
index ef501293402..316e034641d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8124.json
@@ -1 +1 @@
-{"SUTENT": 6.761427127662978, "null": 1.3460869534193425}
\ No newline at end of file
+{"ALIMTA": 5.255493209810065, "ARIPIPRAZOLE": 6.073520351984072, "KALETRA": 5.530604254860135, "MIDAZOLAM": 7.827812131677235, "OLANZAPINE": 4.34587371598508, "TENOFOVIR": 40.97437493593878, "TRUVADA": 1.3075151386068549, "VIREAD": 21.26200462109204, "ZYPREXA": 3.201542183250081, "null": 5.7986427856528895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8125.json
index b54817c20a6..d2c5a783fb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8125.json
@@ -1 +1 @@
-{"null": 1.0366291442133122}
\ No newline at end of file
+{"CONTRAST": 262.02365246068035, "OPTIMARK": 639.5132296893016, "null": 2.3076484309256604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8126.json
index 89dbbdb6dcb..8c125601cf6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8126.json
@@ -1 +1 @@
-{"null": 1.9453425062428755}
\ No newline at end of file
+{"ABACAVIR": 0.4431245821723371, "ABATACEPT": 1.0181747653109583, "ABILIFY": 0.2278710633697392, "ADALIMUMAB": 0.1782864344973161, "AERIUS": 1.4939968034333784, "AFINITOR": 0.5114139375856581, "AIMOVIG": 2.4012826628907606, "APIDRA": 0.6331533254628894, "APROVEL": 1.2062688999392033, "ARAVA": 2.431368560485615, "ATAZANAVIR": 7.954052272006041, "ATRIPLA": 3.398205015927867, "AUBAGIO": 2.645091506088603, "AVASTIN": 0.3651010879034345, "BELIMUMAB": 21.242642033522174, "BENLYSTA": 3.112717149961753, "BIKTARVY": 1.1697714374286494, "BOSULIF": 1.0326959035808954, "BOTULINUM": 36.396485351760944, "BRAFTOVI": 1.126262668975079, "BRIVARACETAM": 2.759663047232106, "BUDESONIDE": 0.1651755793057241, "BYDUREON": 1.807783216208474, "BYETTA": 4.562489053280524, "CELECOXIB": 0.916803624723066, "CELLCEPT": 0.4747632257831389, "CHAMPIX": 0.1668531253959895, "CIALIS": 2.447686639967041, "CICLOSPORIN": 0.1310899829226358, "CIMZIA": 1.750396699370158, "CLOPIDOGREL": 0.1886107286122265, "COMBIVIR": 2.05567252176263, "COMIRNATY": 0.0782967831342195, "COSENTYX": 1.702882976052024, "CRIXIVAN": 107.99090723893724, "CYMBALTA": 0.392007772864519, "DARUNAVIR": 1.9492020077931664, "DEXAMETHASONE": 0.2746123774373024, "ELIQUIS": 1.8982495644613453, "EMPAGLIFLOZIN": 2.218242271339193, "EMTRIVA": 5.843639757490621, "ENBREL": 1.418870226040573, "ENTRESTO": 0.5401053606314848, "ENTYVIO": 0.9578452204133072, "EPIVIR": 2.301166811838787, "ESBRIET": 2.472880589338075, "ESOMEPRAZOLE": 1.80562747739033, "EVISTA": 1.1124504115561964, "EXFORGE": 0.901950486011224, "EXJADE": 2.822102014578238, "FAMPYRA": 3.177163102106419, "FASENRA": 0.7483150037102181, "FASLODEX": 0.6438002192343798, "FEBUXOSTAT": 3.4735292273318694, "FENTANYL": 0.2465542111988883, "FIRDAPSE": 3.364580774980174, "FORSTEO": 4.076705836822811, "FORXIGA": 1.4050697338949565, "GALAFOLD": 4.086116711126249, "GARDASIL": 0.3363389174328768, "HARVONI": 0.7291555938745462, "HEMLIBRA": 4.423643886857319, "HEPSERA": 1.6661427568126748, "HIZENTRA": 4.988279803810406, "HUMALOG": 1.6057823310910608, "HUMIRA": 2.09872884213712, "HYDROCORTISONE": 1.2175852927586277, "IBRANCE": 1.427127201353469, "INDINAVIR": 6.732413576584092, "INLYTA": 0.3928841950928169, "INSULIN": 0.5679626870026986, "ISENTRESS": 2.045691091208112, "JAKAVI": 0.3395305750260189, "JANUMET": 5.328687474197184, "JANUVIA": 4.020384811130277, "JARDIANCE": 2.3521476366282235, "KAFTRIO": 0.8910276473208649, "KALETRA": 0.4788054041647493, "KEPPRA": 0.960564841382411, "KEYTRUDA": 0.1559241301064545, "KIVEXA": 13.420026685681588, "LACOSAMIDE": 1.242875124655892, "LANTUS": 1.1060687724472278, "LEMTRADA": 0.7279630360381485, "LEVEMIR": 0.915018465867846, "LEVETIRACETAM": 0.2885651187838944, "LONSURF": 0.8272084590349811, "LYRICA": 0.967553636677588, "MEKINIST": 0.8120507050496448, "MEPOLIZUMAB": 0.3347458713003136, "METHOTREXATE": 0.89478818052804, "MICARDIS": 0.5093112043930749, "MIMPARA": 2.401741344584049, "NEXAVAR": 0.1883378615348604, "NORVIR": 24.019914985710788, "NUCALA": 0.7705784772291356, "OFEV": 0.536273036455252, "OLANZAPINE": 0.1564634354182304, "OPSUMIT": 0.4466418791801282, "ORKAMBI": 1.9579428984218532, "OZEMPIC": 6.053237934785472, "PANTOPRAZOLE": 0.5476702401971868, "PEGASYS": 1.0897832988627765, "PEGINTRON": 0.5176325871383922, "PLAVIX": 0.934295665846918, "PROPRANOLOL": 4.06118259717249, "REMICADE": 1.6455385574808428, "REVATIO": 0.6924278012191514, "REYATAZ": 95.47854232241838, "RINVOQ": 1.1391847687928394, "RITUXIMAB": 0.4322114083998722, "ROACTEMRA": 0.7632573363818053, "RUBRACA": 1.1867404919348852, "RUCONEST": 8.539055056641965, "SAXENDA": 2.6419277717654777, "SHINGRIX": 0.2259815373118789, "SIMPONI": 2.570885487295845, "SOLIRIS": 1.333699952843948, "SPIKEVAX": 0.1059106061492055, "SPINRAZA": 5.844654408180429, "SPRYCEL": 1.06965305440428, "STELARA": 2.410575946914446, "STRIBILD": 3.558028936981078, "SUBOXONE": 0.8672596464256419, "SUTENT": 0.7274992406543844, "TASIGNA": 0.9881466697153, "TERIPARATIDE": 6.143134211067866, "TOBRAMYCIN": 2.80935944168595, "TOVIAZ": 1.3869361554141757, "TOZINAMERAN": 0.2386649520429083, "TRELEGY": 0.5196065080964335, "TREMFYA": 4.386937073744599, "TRULICITY": 1.8587407275098649, "TRUVADA": 2.6806285097701816, "VAXZEVRIA": 0.0322856770406799, "VELTASSA": 1.5559711179124336, "VIAGRA": 1.0041577735481282, "VICTOZA": 3.0275882904565345, "VIMPAT": 1.2821431068669242, "VIREAD": 4.138736697656153, "VOTRIENT": 0.6580914624600324, "XARELTO": 1.1601941803054936, "XELJANZ": 3.670221436467374, "XOLAIR": 0.926050426604123, "XTANDI": 0.9601830978328116, "XYREM": 3.267825580540081, "ZOSTAVAX": 2.32842264592489, "ZYPREXA": 0.4401337707080529, "null": 1.0178118066990796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8127.json
index 2ffb84fdf7d..e749f222fd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8127.json
@@ -1 +1 @@
-{"BRILIQUE": 15.563762163501735, "CLOPIDOGREL": 11.220882473796092, "ELIQUIS": 3.757013504805918, "PLAVIX": 7.997916733861288, "SUTENT": 1.8717544930968788, "null": 1.76683645719376}
\ No newline at end of file
+{"APIXABAN": 11.504879037723525, "ARANESP": 0.7144642416648651, "ATRIPLA": 41.38825144499997, "AVANDIA": 1.35829056998834, "BASILIXIMAB": 3.632196255333132, "BIKTARVY": 0.8996603262353347, "BYETTA": 1.2287746699953, "CELLCEPT": 1.2037075255948058, "CICLOSPORIN": 2.5167608407677906, "COMIRNATY": 0.0188506514975576, "ELIQUIS": 0.4738410319633642, "ENTRESTO": 0.3681335876719212, "EXFORGE": 0.6490836606673923, "EXJADE": 0.6594651732845938, "HARVONI": 1.4394821460589975, "HEPSERA": 2.702581694389534, "HUMALOG": 1.0121981908669526, "IBRANCE": 0.196319490969228, "INSULIN": 0.6579190181101628, "JANUMET": 1.6585443499018755, "JANUVIA": 1.1425655259706191, "JARDIANCE": 0.3644216922607141, "KALETRA": 1.9515464579340327, "KEPPRA": 0.1827088052785714, "KEYTRUDA": 0.2111174915354479, "LANTUS": 0.8736199583861489, "PEGASYS": 0.1627156175348473, "PLAVIX": 0.2757712251108676, "RASILEZ": 4.016217036440081, "SPIKEVAX": 0.0137030811109134, "STELARA": 0.2023129032163532, "STRIBILD": 14.935658524312323, "SUTENT": 0.0918606607886436, "TIVICAY": 3.4347291586537425, "TOZINAMERAN": 0.069973545532773, "TRESIBA": 4.670488686917671, "TRUVADA": 29.879319102877165, "VIREAD": 12.039688814163268, "XELJANZ": 0.2708185723561441, "ZOSTAVAX": 0.716523784313518, "ZYPREXA": 0.3341431757365295, "null": 0.3991837246104169}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8128.json
index f0015da293a..0390b980c62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8128.json
@@ -1 +1 @@
-{"KEPPRA": 5.632142380002036, "SUTENT": 11.86010907197928, "null": 1.4010701190625323}
\ No newline at end of file
+{"ABACAVIR": 2.357228084229724, "AFINITOR": 0.4443763161260323, "AIMOVIG": 0.8964531231916018, "ALEMTUZUMAB": 2.1588378328677718, "ALIMTA": 8.349366848945547, "AMIKACIN": 18.60198113024841, "ATAZANAVIR": 6.15629814904412, "ATRIPLA": 0.9134573638132676, "AZATHIOPRINE": 4.3396048289088665, "BASILIXIMAB": 25.10255011739549, "BIKTARVY": 1.923533078826721, "BUDESONIDE": 0.9190033199664296, "BUSULFAN": 3.272558323038754, "CANCIDAS": 3.8669372898050254, "CARMUSTINE": 4.777767750232702, "CASPOFUNGIN": 10.695950586667625, "CELLCEPT": 5.045974908428523, "CICLOSPORIN": 29.65585497156069, "CIDOFOVIR": 105.4011116265018, "CLOPIDOGREL": 0.5945174295359834, "CUBICIN": 2.8606416350262838, "CYTARABINE": 1.9660531451149528, "DARUNAVIR": 6.760328574636772, "DELAMANID": 4.955711867891541, "DEXAMETHASONE": 1.449249225992153, "DOCETAXEL": 1.2985134329256514, "DOLUTEGRAVIR": 122.68740612527888, "DULOXETINE": 1.649522723777486, "EFAVIRENZ": 10.862407909727676, "EMTRICITABINE": 50.58966648649003, "EXJADE": 1.3475691155895375, "GANCICLOVIR": 17.35222385259939, "HEPSERA": 6.925310611766496, "IBUPROFEN": 0.861963596478135, "IPILIMUMAB": 1.6919788221840868, "KALETRA": 2.8190239226586877, "KEYTRUDA": 1.8889094599003649, "LAMIVUDINE": 4.099949308267737, "LEVOFLOXACIN": 1.0859788613232289, "LOPINAVIR": 8.724465001595059, "LUTETIUM": 17.83469840638457, "MANNITOL": 19.14072067562964, "METHOTREXATE": 2.1373467033537845, "MYCOPHENOLATE": 6.677698022101296, "NORVIR": 5.664561806643916, "OLANZAPINE": 0.4897952145703208, "OPDIVO": 1.3086653210799828, "PEMBROLIZUMAB": 4.461130603064338, "PEMETREXED": 17.20789078806694, "POSACONAZOLE": 7.330339632259821, "STRIBILD": 16.302223077865932, "SUTENT": 0.4193811229216182, "TACROLIMUS": 26.15257354673421, "TENOFOVIR": 36.3441495212082, "TOBRAMYCIN": 15.63470794955351, "TRUVADA": 1.6775561702357298, "VIREAD": 16.632416206986555, "VORICONAZOLE": 3.982611378022996, "null": 1.622092142678785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8129.json
index eb15bcdbc3f..2c33c5d9f32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8129.json
@@ -1 +1 @@
-{"LATUDA": 25.67288451600384, "TOZINAMERAN": 1.1929455894730838, "null": 2.307371102598474}
\ No newline at end of file
+{"BUPRENORPHINE": 16.33678459881442, "null": 1.7100568114868382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/813.json
index fc81a1596a9..a6953db0184 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/813.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/813.json
@@ -1 +1 @@
-{"ASPARAGINASE": 276.1900724893627, "null": 1.043373384120751}
\ No newline at end of file
+{"BENLYSTA": 6.886619903555781, "COMIRNATY": 1.015421945398712, "ELIQUIS": 7.993611566290993, "GARDASIL": 6.271562033230672, "SOLIRIS": 6.000474285740672, "SPIKEVAX": 0.3724149537355389, "TOZINAMERAN": 1.078407256743604, "VAXZEVRIA": 0.5186702507375587, "null": 0.6727309276799546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8130.json
index e1abafb4bb4..5bd9c12afb2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8130.json
@@ -1 +1 @@
-{"null": 1.3105706451927457}
\ No newline at end of file
+{"VELTASSA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8131.json
index faeca22aeee..3a9ffae8ba7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8131.json
@@ -1 +1 @@
-{"ELIQUIS": 2.584740837872284, "RINVOQ": 14.0273953179269, "STELARA": 8.10291956593776, "null": 1.139753555962157}
\ No newline at end of file
+{"ENBREL": 25.82597090812718, "null": 0.2316801762743038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8132.json
index 2a5ddeaf3b3..354c7b90694 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8132.json
@@ -1 +1 @@
-{"AFINITOR": 2.0283300029211078, "APROVEL": 2.743262800664838, "BRIDION": 3.0040916574661995, "BRILIQUE": 1.8699359818021903, "COAPROVEL": 4.347240129858233, "ENTRESTO": 1.3159940904580112, "EXFORGE": 1.3054766542640357, "IBUPROFEN": 2.673700126692938, "LEVOFLOXACIN": 1.6987525877634857, "MIDAZOLAM": 1.5412004852808876, "OMALIZUMAB": 1.483270033155507, "RASILEZ": 3.5821056342397206, "ROACTEMRA": 1.8408366456198104, "SYCREST": 10.430493009811324, "XOLAIR": 1.5499523326470952, "null": 5.380345900740148}
\ No newline at end of file
+{"XTANDI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8133.json
index 61e66447805..a26a86d9ece 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8133.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.0676809168094492, "TOZINAMERAN": 1.0284994572314936, "null": 1.430169537850578}
\ No newline at end of file
+{"AFINITOR": 1.2219841666985998, "ALIMTA": 2.9074035701178365, "ARAVA": 0.1255273851539643, "ATRIPLA": 0.4364000150868477, "AVASTIN": 6.386808746670626, "BENLYSTA": 1.002247163465768, "BETAFERON": 4.276446191708813, "BEVACIZUMAB": 6.040599789249148, "CABOMETYX": 5.82799880222245, "CELLCEPT": 5.150199619169999, "CICLOSPORIN": 15.715747287107291, "COMIRNATY": 0.4705765298502276, "CYRAMZA": 54.95641009513694, "ENTYVIO": 1.3525104430013448, "EXFORGE": 1.3641810097621074, "EXJADE": 0.8241735460390717, "GANCICLOVIR": 3.5443542776729555, "GARDASIL": 0.4944061929494955, "HARVONI": 1.9622617031569856, "HUMAN": 2.502888953601884, "INLYTA": 4.631625972329708, "INTRONA": 6.62360406406957, "JANUVIA": 0.994005708699793, "KEYTRUDA": 3.1503311454662084, "LAMIVUDINE": 5.450446214539015, "LANTUS": 0.2290810838175344, "LENVIMA": 15.119008861741564, "MYCOPHENOLATE": 7.424659521508784, "NEXAVAR": 7.691775605357985, "OFEV": 2.398954613152664, "OMALIZUMAB": 1.3599122283774443, "OPDIVO": 1.2011143308942198, "PAZOPANIB": 6.527876194109605, "PEGASYS": 2.2435592816047065, "PEGINTERFERON": 1.6849573592441076, "PEGINTRON": 0.9984840908290408, "PEMBROLIZUMAB": 1.7074328751062942, "RAPAMUNE": 6.082112611179107, "RIBAVIRIN": 1.7171494396092837, "SIMPONI": 1.701603296876508, "SOLIRIS": 1.3117012441562, "SPIKEVAX": 0.1892289513488896, "SPRYCEL": 4.127880030466489, "STELARA": 0.4757748424799614, "STIVARGA": 3.939537064570632, "SUNITINIB": 23.75094271928633, "SUTENT": 8.49909098633634, "TAMIFLU": 1.0264362579230293, "TASIGNA": 1.1255371417582738, "TOZINAMERAN": 0.549343860334191, "TRUVADA": 0.517459216845639, "VAXZEVRIA": 0.0901992419697203, "VIREAD": 3.0242179030742102, "VOTRIENT": 4.746626224643749, "null": 0.9873770109130507}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8134.json
index 43b11244714..45e87f0ec2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8134.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6903176641232984, "TOZINAMERAN": 1.9987012787753384, "null": 2.43261197163443}
\ No newline at end of file
+{"CICLOSPORIN": 279.6137283017031}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8135.json
index 86c04291418..0eab4b0f114 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8135.json
@@ -1 +1 @@
-{"SUTENT": 5.149123071304462, "null": 1.914778172126492}
\ No newline at end of file
+{"ENBREL": 44.19294169055031, "null": 1.0666034920738252}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8136.json
index 51b5ac8a3b4..3f3680ccf60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8136.json
@@ -1 +1 @@
-{"null": 1.3460869534193425}
\ No newline at end of file
+{"ARAVA": 0.2223959956674915, "AUBAGIO": 2.4702443207889035, "BUDESONIDE": 1.059369790613946, "CANNABIDIOL": 22.40117854522213, "CIMZIA": 1.2237871665607334, "COMIRNATY": 0.2885831148104824, "CYMBALTA": 1.2138498909787774, "ELIQUIS": 1.0269233516688436, "ENBREL": 1.6348742490279735, "FORSTEO": 2.4100372250050723, "HUMALOG": 3.8692088440114976, "HUMIRA": 5.137248728169712, "HYDROCORTISONE": 15.210742969344835, "IBRANCE": 1.5301839078466912, "IBUPROFEN": 7.566259766154312, "JARDIANCE": 1.3631951454619853, "LANTUS": 1.4972388764286864, "LYRICA": 4.998473631575979, "MEPOLIZUMAB": 4.544221162257472, "OCEAN": 283.4974384664607, "OMALIZUMAB": 6.083719585313036, "RINVOQ": 3.6887652585268, "SIMPONI": 2.408333567435322, "SPIKEVAX": 0.2914786065228433, "STELARA": 0.9057525082907454, "SUBOXONE": 4.50293383839562, "SUTENT": 0.635070667502576, "TOZINAMERAN": 1.6067229418961917, "VAXZEVRIA": 0.2570591520412079, "VIAGRA": 7.345848160742834, "XELJANZ": 7.294766559017453, "XTANDI": 1.902470670397213, "ZOSTAVAX": 2.6105396598163177, "null": 0.976123571317992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8137.json
index 8fc478ccb1d..04b7fc3c43f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8137.json
@@ -1 +1 @@
-{"AFINITOR": 3.8310760341552657, "CICLOSPORIN": 5.566217015564675, "COSENTYX": 1.844279634699496, "DOCETAXEL": 6.127561723515743, "IBRANCE": 1.5776746707259894, "NEXAVAR": 3.669896184241869, "PEGASYS": 1.1702506408295468, "PEGINTRON": 3.4065075693555658, "SUTENT": 2.4040576053361056, "TOZINAMERAN": 1.0991287919947197, "XELJANZ": 1.1550523509901054, "null": 1.418509841007094}
\ No newline at end of file
+{"COMIRNATY": 0.6816822063924481, "null": 1.1841175056283402}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8138.json
index 97349b03b99..daa5b5557fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8138.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 5.192241620809898, "GARDASIL": 27.801345092527264, "MENVEO": 18.47153807110239, "MMRVAXPRO": 2.942719119286678, "NIMENRIX": 10.97674843661849, "null": 2.0781264415650127}
\ No newline at end of file
+{"null": 1.3603685642886685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8139.json
index 45ada410440..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8139.json
@@ -1 +1 @@
-{"BRIVIACT": 25.358977684173944, "CICLOSPORIN": 1.0986958853719966, "GARDASIL": 3.0766820110088275, "KEPPRA": 9.583248395021304, "LACOSAMIDE": 27.920142904707436, "LEVETIRACETAM": 33.059397324019265, "MIDAZOLAM": 6.42482942222802, "MMRVAXPRO": 2.3288767526889287, "OLANZAPINE": 2.711712706108903, "ZONISAMIDE": 106.94908801847065, "null": 2.164932575284262}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/814.json
index f5580b1aa48..2c261eeb256 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/814.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/814.json
@@ -1 +1 @@
-{"ADALIMUMAB": 11.189783138012508, "ANAKINRA": 2.0634008955343472, "APIDRA": 1.6780016103691744, "AUBAGIO": 2.953012411180084, "BENLYSTA": 1.398430749705812, "BYETTA": 1.6076254233064486, "CIMZIA": 1.394018900689099, "COSENTYX": 1.0961662604984606, "CYMBALTA": 1.245163352846081, "ELIQUIS": 4.283560731257727, "ENBREL": 1.0863830426448475, "ENTYVIO": 1.3449239042689125, "FASLODEX": 1.746964074757461, "FIRDAPSE": 3.96975168885958, "FORSTEO": 1.4227359539859954, "HUMALOG": 3.3259737918441337, "IBRANCE": 2.053451511423694, "INLYTA": 1.650271460084758, "INSULIN": 1.3588445756792225, "LANTUS": 5.180304724963078, "LYRICA": 10.10560767904088, "SIMPONI": 1.9220882660238576, "SPRYCEL": 2.2719091286628488, "SUBOXONE": 4.939207972895123, "TOVIAZ": 4.491182956468194, "TRULICITY": 2.1226926059458373, "VIAGRA": 16.732121240186682, "XELJANZ": 4.741914452090682, "XTANDI": 1.4607035611018822, "XYREM": 8.387743550887034, "ZOSTAVAX": 2.864517250982201, "null": 1.2899846195925289}
\ No newline at end of file
+{"null": 1.9007439671806237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8140.json
index e4b2652f84c..b32d32905d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8140.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"ABACAVIR": 1.1382629970787523, "ABATACEPT": 1.475732453402969, "ABILIFY": 0.7995129744826226, "ADALIMUMAB": 0.1447484937432291, "ARAVA": 3.5035389997057163, "ATRIPLA": 0.4777082259934319, "AVANDIA": 1.4011359187360723, "BEVACIZUMAB": 5.363456950588303, "BUPRENORPHINE": 0.8623152519621898, "CIMZIA": 0.3235480702479429, "COMBIVIR": 2.093061644280116, "COMIRNATY": 0.4454263020575436, "COSENTYX": 0.9150333403722236, "CYMBALTA": 0.8962046597284407, "ELIQUIS": 0.4671930718684328, "FASLODEX": 2.979615705217792, "GARDASIL": 0.6825769715354683, "HUMALOG": 3.1428880003393664, "IBRANCE": 2.6266081457591137, "INSULIN": 1.0140316344770277, "KEPPRA": 0.5871949413794139, "LANTUS": 1.753432406917527, "LEVEMIR": 1.7657568184007002, "LEVOFLOXACIN": 1.115148742483443, "LYRICA": 8.558186545403876, "MEPOLIZUMAB": 1.160678665473163, "MIDAZOLAM": 2.603320472459751, "PEGASYS": 0.4256629067146465, "PEGINTRON": 0.6594949029828535, "PLAVIX": 1.1257168290831574, "SHINGRIX": 3.6590169976077367, "SIMPONI": 0.4854530750854799, "SPIKEVAX": 0.3406468588024013, "SUBOXONE": 2.3012144959134653, "SUTENT": 0.2223354575488642, "TOZINAMERAN": 2.575643518670831, "TRUVADA": 0.1690693375372796, "VAXZEVRIA": 0.6402231433044911, "VIAGRA": 4.288157946079251, "XELJANZ": 1.8372032574616777, "ZOSTAVAX": 11.337660214875507, "ZYPREXA": 0.9343338585017624, "null": 1.1823771337727516}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8141.json
index ea3c9bee5f1..adea616a844 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8141.json
@@ -1 +1 @@
-{"METFORMIN": 142.19237395618146, "PANTOPRAZOLE": 40.74595820885498}
\ No newline at end of file
+{"null": 1.6086976435080844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8142.json
index ad035bc1c2e..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8142.json
@@ -1 +1 @@
-{"ARAVA": 2.312648863525, "DOCETAXEL": 36.672353537887865, "SOMATROPIN": 271.355272624483, "null": 1.2369428552576172}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8143.json
index 9190a8b3e62..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8143.json
@@ -1 +1 @@
-{"COMIRNATY": 1.8002353542463998, "COVID19": 1.4268048649716747, "GARDASIL": 1.245677849720311, "MMRVAXPRO": 3.825523691449448, "TOZINAMERAN": 2.761019116234644}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8144.json
index 47447fcfdf9..51ce01c9af8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8144.json
@@ -1 +1 @@
-{"COMIRNATY": 2.1904942706014165, "SPIKEVAX": 1.1238836389381717}
\ No newline at end of file
+{"null": 1.145626223782917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8145.json
index b204ce60e51..caa3b6409dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8145.json
@@ -1 +1 @@
-{"COSENTYX": 77.85689721946959}
\ No newline at end of file
+{"ABACAVIR": 0.9205772859301096, "ABILIFY": 0.3212541101345927, "AIMOVIG": 0.6244140012677223, "ANAKINRA": 0.6845630738991823, "APIDRA": 1.0904106711124482, "ASPARAGINASE": 1.5065960466921664, "ATEZOLIZUMAB": 9.808601536112944, "ATRIPLA": 0.3683276043279637, "AUBAGIO": 0.5661091102003268, "AVANDIA": 0.3314266771641024, "AVASTIN": 0.7223460690510348, "AZATHIOPRINE": 0.7165661549289347, "BENLYSTA": 1.0582075890807454, "BEVACIZUMAB": 3.1138047651033456, "BIKTARVY": 7.323679230407762, "BUPRENORPHINE": 1.116128891246054, "CAPECITABINE": 0.7622321345905684, "CELLCEPT": 0.8085494065992357, "CELSENTRI": 15.924331632167846, "CHAMPIX": 0.6119769656437597, "CICLOSPORIN": 1.0754765164323457, "CIMZIA": 0.1824445437876269, "CLOPIDOGREL": 0.5424290773194937, "COMBIVIR": 1.1802652792836386, "COMIRNATY": 0.9291367168463636, "COSENTYX": 2.240452753873656, "CYMBALTA": 0.5531430197940033, "CYTARABINE": 2.6596998601594053, "DEXAMETHASONE": 1.0778355715581125, "DOXORUBICIN": 0.9312747212434902, "EFAVIRENZ": 2.9949014201624644, "ELIQUIS": 0.4854728376229348, "ENBREL": 0.6425172169371648, "ENOXAPARIN": 1.5882679185271216, "ENTRESTO": 0.4356276725007721, "ENTYVIO": 0.4511867616204349, "EPIVIR": 4.450318610071912, "EXJADE": 0.5731283648677529, "FAMPYRA": 1.1017421009706172, "FASENRA": 1.2475922624486575, "FASLODEX": 0.4872995379034384, "FENTANYL": 1.9130591119072848, "FILGRASTIM": 2.3308717899712668, "GARDASIL": 2.8370247140589893, "HARVONI": 1.0280276422241688, "HUMALOG": 0.8104042433066295, "HUMIRA": 0.5165642062572208, "IBRANCE": 0.4966189313862518, "IBUPROFEN": 0.4917782775281558, "INLYTA": 0.6271751965899806, "INTELENCE": 17.010059857792, "ISENTRESS": 1.4674634141472491, "JAKAVI": 0.7379531015137918, "JANUVIA": 0.3754653777130002, "KALETRA": 1.08676548520466, "KEPPRA": 0.9953253705780196, "KEYTRUDA": 0.9459751576327948, "KYMRIAH": 6.08858583728322, "LANTUS": 0.6724070089752175, "LATUDA": 0.7223173362368744, "LEMTRADA": 0.8101521253179704, "LEVETIRACETAM": 0.7579331353629543, "LEVOFLOXACIN": 2.0762520920592222, "LYRICA": 1.3648001346717549, "MEKINIST": 0.5079205449476168, "METHOTREXATE": 0.4053028994350816, "MIDAZOLAM": 2.526573055262931, "MMRVAXPRO": 0.2732497908473681, "NOT": 4.132229480147723, "OLANZAPINE": 1.2067131502076711, "OPDIVO": 0.8092142516429606, "OXYBUTYNIN": 5.71662493253048, "PEGASYS": 0.8438239595397096, "PEGINTRON": 1.095236291406693, "PLAVIX": 0.5370388635388045, "PREGABALIN": 2.5221961149225134, "RASBURICASE": 19.946357158042847, "SHINGRIX": 0.7153825979328814, "SIMPONI": 0.220894922533232, "SOLIRIS": 1.5391456732037905, "SPIKEVAX": 0.4493236016753696, "SPINRAZA": 1.193319235299806, "STELARA": 0.5264817134879776, "SUBOXONE": 0.4474257134780227, "SUTENT": 0.3489633434132509, "TAMIFLU": 0.4806922671197484, "THIOTEPA": 14.202169728341207, "TIVICAY": 4.602720773527096, "TOVIAZ": 1.5813697823417938, "TOZINAMERAN": 1.0049426797796257, "TRIENTINE": 75.2965792521512, "TRIUMEQ": 2.588420505184052, "TRUVADA": 0.1734409501513926, "TWINRIX": 2.3121264873124527, "VAXZEVRIA": 0.4997104034507202, "VFEND": 1.3326792665817937, "VIAGRA": 0.6625333859387841, "VORICONAZOLE": 5.956735772289727, "XELJANZ": 0.3565910188060621, "XOLAIR": 0.6421864450527207, "XTANDI": 0.5926110048683331, "YESCARTA": 3.036023505601178, "ZOSTAVAX": 2.71737474787698, "ZYPREXA": 0.6493956315867423, "null": 1.4231029779287507}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8146.json
index 03989a451ac..04d446d71ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8146.json
@@ -1 +1 @@
-{"GARDASIL": 4.62571182282145, "JANUMET": 15.16844149877871, "JANUVIA": 40.74743326665609, "NAGLAZYME": 53.80221331505649, "ZOSTAVAX": 10.46303975015456, "null": 1.2103295116805468}
\ No newline at end of file
+{"null": 0.489587685703479}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8147.json
index 3d09c785450..26c972bb1a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8147.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0392454872287444, "COSENTYX": 9.48165577894944, "ENTYVIO": 3.724640344900476, "GARDASIL": 3.8434976311010542, "IBUPROFEN": 1.5122632690059148, "MMRVAXPRO": 5.315952342238215, "NIMENRIX": 3.293398690562231, "RINVOQ": 3.632839904345888, "ROACTEMRA": 2.988708181254945, "SIMPONI": 12.527533604682697, "SOLIRIS": 1.2529044916439174, "STELARA": 3.834665468510936, "SYNAGIS": 4.117114807066312, "SYNFLORIX": 50.87302756135354, "TOZINAMERAN": 1.5123796470193338, "VFEND": 1.8192691713119156, "XOLAIR": 1.194491534379206, "null": 1.043901780111266}
\ No newline at end of file
+{"NUTROPIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8148.json
index 7c4ef0a5c1a..3cd674cf8f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8148.json
@@ -1 +1 @@
-{"AFINITOR": 2.502713380858896, "AUBAGIO": 4.924505224959719, "BENLYSTA": 4.632286961005069, "CIMZIA": 2.5644337830174586, "COSENTYX": 9.125719320318892, "ELIQUIS": 1.6379916487053758, "ENBREL": 4.109538806857361, "ENTYVIO": 2.2600848610937887, "FORSTEO": 2.900563769782061, "HIZENTRA": 6.940010287625394, "HUMIRA": 7.954898425754529, "IBRANCE": 2.5033381256856058, "METHOTREXATE": 8.726740897596994, "PEGASYS": 2.544499742450005, "PEGINTRON": 2.4929345199523385, "RINVOQ": 2.9059059122796618, "RITUXIMAB": 2.464687561731058, "ROACTEMRA": 4.368585701232323, "SIMPONI": 14.533739033871369, "STELARA": 10.34106619230676, "SUTENT": 2.943595622265882, "VOTRIENT": 1.7238177274079536, "XELJANZ": 12.1726670781839, "XTANDI": 1.3160531048667246, "ZOSTAVAX": 1.256948343972719}
\ No newline at end of file
+{"ABILIFY": 1.1587009634043184, "ACTOS": 1.5539901319752272, "AERIUS": 2.3144294318440752, "AFINITOR": 0.7830181222083048, "AIMOVIG": 0.3373527621087099, "ALEMTUZUMAB": 0.5969488693259394, "APIDRA": 4.3560196103112325, "ARAVA": 0.0458466324441845, "ARIPIPRAZOLE": 0.7658161816974208, "ATRIPLA": 0.0606481493595615, "AUBAGIO": 0.2320772718068245, "AVAMYS": 0.7094652097775352, "AVANDIA": 0.1764873672229515, "BENLYSTA": 2.2382170578450133, "BIKTARVY": 1.7782291136486008, "BRILIQUE": 0.6749669654974083, "BRINTELLIX": 3.5577229908414343, "BRIVIACT": 2.0987424382245714, "BUDESONIDE": 0.2667385516605693, "BUPRENORPHINE": 0.4719839714809729, "BYDUREON": 1.1612966930488977, "BYETTA": 0.6658027301742132, "CHAMPIX": 5.365025643749227, "CIMZIA": 0.1322620613052398, "CIRCADIN": 2.648308451035515, "CLOPIDOGREL": 0.1442215973343169, "COMIRNATY": 0.2735569023436267, "COMTAN": 1.8454866263038776, "COSENTYX": 0.5886135114199854, "CYMBALTA": 2.145381890674427, "DAKLINZA": 4.355902856228382, "DEXAMETHASONE": 0.3318697093019236, "ELIQUIS": 0.7046117351949561, "ENBREL": 0.3360061214992692, "ENTYVIO": 0.4590223751646132, "ESBRIET": 0.3674718998448272, "EXFORGE": 2.931795259301165, "EXJADE": 0.2249509095742828, "FAMPYRA": 1.0461297300015118, "FASENRA": 0.5721956593896964, "FASLODEX": 0.5176726878637031, "FIRDAPSE": 2.1004215225844822, "FORSTEO": 1.8028356673502777, "FORXIGA": 0.3513716584676103, "FYCOMPA": 2.674890638713748, "GALVUS": 1.5881593561175509, "GARDASIL": 0.3406364922991696, "GLYCOPYRRONIUM": 3.25780036988099, "HUMALOG": 0.8723927664234258, "HYDROCORTISONE": 0.6804771827363596, "IBRANCE": 1.6649613826989664, "IBUPROFEN": 0.3949316567060682, "INCIVO": 0.533277029652545, "INCRUSE": 1.193275122876397, "INLYTA": 0.4139242977587573, "INSULIN": 0.9265529155940054, "INTRONA": 1.5028687770410207, "JANUMET": 0.6922019647169092, "JANUVIA": 0.2772341924928841, "JARDIANCE": 0.4472159557332666, "KAFTRIO": 1.3345500430475954, "KEPPRA": 2.533706847803184, "LANTUS": 3.189269334790811, "LATUDA": 2.082205177468173, "LEMTRADA": 0.750317814824647, "LEVEMIR": 0.4276981333978944, "LEVETIRACETAM": 1.3334744834673138, "LEVOFLOXACIN": 0.9842974308647752, "LYRICA": 2.4624703621063126, "MELATONIN": 1.1372839043025438, "MICARDIS": 0.536587154342082, "MMRVAXPRO": 0.594027347995291, "MULTAQ": 0.9637699734976556, "NEULASTA": 0.5018695790475521, "NIMENRIX": 0.695856250993399, "NUCALA": 1.0890226289886582, "OCALIVA": 2.500585402662928, "OCRELIZUMAB": 0.8875248474587341, "OLANZAPINE": 0.3922835681357119, "OMALIZUMAB": 1.4033095712165895, "OPSUMIT": 0.5242452808791739, "PANTOPRAZOLE": 0.9287736193273356, "PEGASYS": 2.1920055466226738, "PEGINTERFERON": 1.3347058570450403, "PEGINTRON": 2.281610054257478, "PLAVIX": 0.3204822818879217, "PREGABALIN": 1.1499959336449013, "PROLIA": 4.0959464766758495, "RASILEZ": 1.574887218254751, "RELVAR": 1.488870240104622, "RITUXIMAB": 0.4021573247582625, "SAXENDA": 1.3270354966013844, "SILDENAFIL": 1.139141051691991, "SIMPONI": 0.8893683190710776, "SPIKEVAX": 0.2500891560162953, "STALEVO": 3.309137962557001, "STELARA": 0.2115116360457944, "SUBOXONE": 1.3529716502360505, "SUTENT": 0.6501159658575096, "SYCREST": 2.9747076280888964, "TAMIFLU": 0.5782182753288438, "TIVICAY": 2.4960177052602344, "TOUJEO": 3.000444619679882, "TOVIAZ": 1.2904556608729676, "TOZINAMERAN": 1.1149638180365582, "TRELEGY": 1.6659931682189724, "TRULICITY": 0.7131726866972512, "VALSARTAN": 1.3516141941643236, "VAXZEVRIA": 0.5513075988542013, "VIAGRA": 0.5573849619249233, "VIMPAT": 1.2802661154871977, "XELJANZ": 0.9702492683122734, "XOLAIR": 0.814278961222714, "XTANDI": 0.5714279769113088, "XYREM": 5.17106940957871, "ZOSTAVAX": 0.6114215937089934, "ZYPREXA": 1.7222042976254728, "null": 2.526443913417254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8149.json
index 49d9dde2a66..12f809c2b8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8149.json
@@ -1 +1 @@
-{"null": 2.8785313480536923}
\ No newline at end of file
+{"COMBIVIR": 54.92696561304764, "DESCOVY": 65.42523578250851, "null": 9.118749841455768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/815.json
index 898b17e97c7..53e4773667e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/815.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/815.json
@@ -1 +1 @@
-{"ABATACEPT": 25.370515987528453, "ADALIMUMAB": 20.97498451926479, "AIMOVIG": 7.091021193884172, "APREMILAST": 18.11018938569901, "ARAVA": 5.941411951629891, "BENLYSTA": 1.5008604812547286, "BUPRENORPHINE": 14.304654506604487, "BYETTA": 1.2666176428089235, "CIMZIA": 2.121292440533906, "ESBRIET": 5.726245555203179, "HUMALOG": 2.0551448998794077, "LANTUS": 1.750322063137531, "LYRICA": 3.898304783899627, "METHOTREXATE": 1.1247771308514445, "RITUXIMAB": 1.3896244458761091, "SIMPONI": 1.3413316876832877, "SUBOXONE": 2.531594537928948, "TRELEGY": 1.6696677421816428, "VIAGRA": 5.270025736972341, "XELJANZ": 2.226458195748169, "ZOSTAVAX": 1.2013172766238969}
\ No newline at end of file
+{"ARIPIPRAZOLE": 18.30649099055507, "null": 6.300075865500757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8150.json
index 48d13ce8bee..466389e81c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8150.json
@@ -1 +1 @@
-{"null": 1.486439739549122}
\ No newline at end of file
+{"AFINITOR": 0.1415283979570211, "AIMOVIG": 1.1189042648329155, "ALEMTUZUMAB": 0.4458477970874539, "ARAVA": 0.1536200637126427, "AUBAGIO": 2.1950529773093166, "AVAMYS": 0.3053081208364164, "AVASTIN": 0.2872896574989412, "AZILECT": 7.314318115155658, "BENLYSTA": 0.5147751202384911, "BEVACIZUMAB": 0.3937963778889038, "BORTEZOMIB": 2.86210752542952, "BRINTELLIX": 0.2891856489971967, "BUPIVACAINE": 6.504316006591663, "BYDUREON": 0.7677923603588643, "CAPECITABINE": 0.5969704640550711, "CELLCEPT": 0.5035697227459603, "CHAMPIX": 0.1312889478765643, "CICLOSPORIN": 0.179010290325243, "CIMZIA": 0.3280944236520305, "COMIRNATY": 2.744834298849123, "COSENTYX": 0.379129291608399, "CYMBALTA": 1.473673028326529, "DARBEPOETIN": 17.514183820995754, "DARZALEX": 0.6726226020730388, "DESLORATADINE": 2.360310786046996, "DEXAMETHASONE": 0.7684929701914895, "DINUTUXIMAB": 14.104996693691866, "DOCETAXEL": 0.3732119147395994, "DULOXETINE": 0.6970781716400577, "ELIQUIS": 0.2295396986171723, "FAMPYRA": 2.805897543855272, "FASENRA": 0.8055294499257931, "FASLODEX": 1.8513654321121693, "FENTANYL": 0.8431041173080303, "FORSTEO": 2.414078231833297, "FORXIGA": 0.5534068445161099, "FULVESTRANT": 0.6366633039683052, "GARDASIL": 1.760379094098945, "HIZENTRA": 0.4439548348217776, "HUMALOG": 0.3259828138396573, "HUMIRA": 0.463002359963245, "HYDROCORTISONE": 4.919729649132236, "IBRANCE": 0.5667306243709448, "IBUPROFEN": 0.2744596953889555, "ILARIS": 26.18203562747009, "INSULIN": 0.5125136347995947, "IRINOTECAN": 0.653506405900821, "JAKAVI": 0.7198188698007794, "JARDIANCE": 0.1051244424348679, "KEPPRA": 0.2387943549301261, "KESIMPTA": 1.2013275047184675, "KEYTRUDA": 0.2183565171193209, "LANTUS": 0.179167832675629, "LEVOFLOXACIN": 0.5619106569561393, "LYRICA": 4.447104609253191, "MELATONIN": 1.7528664049814389, "MEPOLIZUMAB": 0.4239554562214794, "METHOTREXATE": 0.3867978662663637, "MODERNA": 0.655177620402334, "NEULASTA": 0.7135330378713028, "NEXAVAR": 0.1803252344326204, "NOXAFIL": 2.1974396879125173, "NUCALA": 0.1685245639986589, "OCRELIZUMAB": 1.6074366324374414, "OPSUMIT": 0.2403461904708529, "PEGASYS": 0.2877916622247872, "PEGINTRON": 0.3576236231181486, "PREGABALIN": 0.972446615459422, "QUTENZA": 2.519298233887701, "REVLIMID": 1.1994591866962143, "RINVOQ": 0.7564640296584763, "RITUXIMAB": 0.9832889650776532, "RIVAROXABAN": 2.235073271433804, "SHINGRIX": 10.169741013643447, "SIMPONI": 0.3689153270392535, "SOLIRIS": 0.2037786376255747, "SPIKEVAX": 1.5479230387214415, "SPINRAZA": 0.8437160847090968, "STELARA": 0.9328647050445892, "SUBOXONE": 0.3886940598575734, "SUTENT": 0.2717364173863668, "TAGRISSO": 0.5327931603788135, "TASIGNA": 0.3645388499165755, "TOZINAMERAN": 2.1362104528610644, "TWINRIX": 2.671330428562546, "VAXZEVRIA": 1.821934480397377, "VIAGRA": 0.3697245976866248, "VOTRIENT": 0.1921678501011458, "XELJANZ": 0.7683020288410489, "XOLAIR": 0.4532525476216364, "XTANDI": 0.2673678719853883, "XYREM": 2.436432241168069, "ZOSTAVAX": 7.06289202816355, "null": 0.3746422736627224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8151.json
index 21f00b0152f..0653f53292b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8151.json
@@ -1 +1 @@
-{"null": 1.620560513558541}
\ No newline at end of file
+{"COMIRNATY": 5.535668492140422, "MODERNA": 5.295745608554054, "SHINGRIX": 5.852937535851595, "SPIKEVAX": 2.984415024784666, "TOZINAMERAN": 2.082187028801095, "VAXZEVRIA": 0.7793908164012007, "null": 0.1398375341945636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8152.json
index aed7f714e49..31287b171c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8152.json
@@ -1 +1 @@
-{"AVAMYS": 70.71829513793976}
\ No newline at end of file
+{"null": 2.88677152477758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8153.json
index 9d37dd42b5f..0f940f69f3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8153.json
@@ -1 +1 @@
-{"AIMOVIG": 1.3856674286169892, "FORSTEO": 2.492577333048867, "KEPPRA": 1.5462279620183037, "SUTENT": 1.0255274200092257, "SYCREST": 24.008684659261984, "null": 10.29028265868072}
\ No newline at end of file
+{"ANORO": 304.741275491901, "APIXABAN": 37.42417065214124, "AZATHIOPRINE": 14.446305476996343, "COMIRNATY": 2.0542216194603165, "GARDASIL": 0.9710966147103598, "KEYTRUDA": 0.8242718195570041, "SHINGRIX": 4.00559703262613, "SPIKEVAX": 0.9344594287773152, "TOZINAMERAN": 0.9167026724702853, "TWINRIX": 19.31777602578721, "VAXZEVRIA": 0.4969471892147003, "ZOSTAVAX": 5.399732720225704, "null": 0.3134285707624634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8154.json
index 84a4e376e87..72d7f6b9cb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8154.json
@@ -1 +1 @@
-{"ABATACEPT": 1.077033703693229, "AIMOVIG": 1.3396573892431334, "ANAKINRA": 4.6749299971638365, "ARAVA": 3.683164970564284, "ASPARAGINASE": 1.7330151324498682, "ATRIPLA": 2.7618408752834807, "AUBAGIO": 1.6991723656557884, "AZATHIOPRINE": 6.584551236495692, "BENLYSTA": 1.1389478600214846, "BONVIVA": 6.1082105189143565, "BUPRENORPHINE": 2.271922816643417, "CABOMETYX": 3.4531111992285406, "COSENTYX": 1.267631190116227, "CYMBALTA": 1.1539361209757255, "ELIQUIS": 19.487095391863605, "ENBREL": 1.898927545367328, "EVENITY": 6.273600837694171, "EVISTA": 3.364914961775102, "EXFORGE": 1.5317848595429495, "FASLODEX": 2.627646482387695, "FORSTEO": 2.924460618253312, "IBRANCE": 4.42049864003743, "INLYTA": 1.666195572692051, "JANUVIA": 1.9180574007002105, "KALETRA": 2.513116110078061, "KEPPRA": 2.2524269849908403, "LYRICA": 1.4820988461073192, "METHOTREXATE": 1.8569721111603177, "OCRELIZUMAB": 15.648369038755764, "OFEV": 1.8129997968262872, "PEGASYS": 1.2054183769694264, "PREGABALIN": 4.295694388067568, "RITUXIMAB": 2.513779430353284, "ROACTEMRA": 2.76200650249902, "SIMPONI": 1.855153506423013, "SPRYCEL": 1.8500775250046575, "STELARA": 1.384548594405835, "STRIBILD": 3.680807680656984, "SUBOXONE": 5.24044406874836, "SUTENT": 4.390430415430378, "TOVIAZ": 1.858822201966838, "TRUVADA": 1.3343356222498135, "VIAGRA": 1.9443820739222244, "XELJANZ": 2.827571185794042, "XYREM": 5.840999857338879, "ZOMETA": 10.949681459368056}
\ No newline at end of file
+{"COMIRNATY": 1.6306376046282265, "null": 0.2809401145583824}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8155.json
index 139eed207b8..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8155.json
@@ -1 +1 @@
-{"ATRIPLA": 2.060900128466028, "SUBOXONE": 14.6707835340572, "null": 2.5039820032289364}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8156.json
index ffbe11da367..1679b8eace7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8156.json
@@ -1 +1 @@
-{"ATRIPLA": 8.557413172010012, "BENLYSTA": 8.31033684750177, "BONVIVA": 51.37317514056999, "CIMZIA": 1.122685536479734, "ELIQUIS": 4.15772237659085, "EVENITY": 17.492160552502018, "IBRANCE": 6.649810531628682, "MEPOLIZUMAB": 2.3330810237935387, "OPSUMIT": 3.080356419027641, "PEGASYS": 1.6240596644466567, "PEGINTRON": 1.5285484404737666, "SIMPONI": 14.075450098102824, "STELARA": 2.726978248761246, "STRIBILD": 5.042597811637255, "TRUVADA": 4.667684666002426, "XELJANZ": 1.7718009223805342, "XTANDI": 2.065093327589126, "ZOMETA": 91.64366988596448, "ZYPREXA": 1.0531034164513762}
\ No newline at end of file
+{"TOPOTECAN": 528.8684434796431, "null": 1.051618360694964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8157.json
index 31c8f610ec0..dc95960b108 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8157.json
@@ -1 +1 @@
-{"AIMOVIG": 1.6440897688468834, "ATRIPLA": 35.97492952177401, "AUBAGIO": 1.7258493707686762, "BENLYSTA": 1.5634079708790831, "BONVIVA": 6.912397091587622, "ELIQUIS": 2.1749403755582746, "FORSTEO": 1.61813939306082, "FULVESTRANT": 3.3563262451346207, "HUMIRA": 1.514192105246441, "IBRANCE": 2.051550178106564, "KALETRA": 3.0837466258826325, "KEPPRA": 1.4432370207881202, "SIMPONI": 1.3973513592963425, "STRIBILD": 21.65263019670649, "SUBOXONE": 3.708419634774249, "TRUVADA": 16.45140878548545, "VIREAD": 8.76327400373845, "XELJANZ": 1.2720772967701814}
\ No newline at end of file
+{"CANNABIDIOL": 545.5897569526122, "QARZIBA": 2551.4870964439315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8158.json
index 81b7d3b0a48..af70cd74e27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8158.json
@@ -1 +1 @@
-{"ASPARAGINASE": 110.99681463570089, "null": 1.987088276740272}
\ No newline at end of file
+{"COMIRNATY": 1.1731431894627606, "null": 0.3059555404270954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8159.json
index 4f74b543004..15992abb587 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8159.json
@@ -1 +1 @@
-{"ATRIPLA": 10.06724456053118}
\ No newline at end of file
+{"COMIRNATY": 0.1658211984025206, "null": 1.6037089372333893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/816.json
index 14335807dbc..319bb935474 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/816.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/816.json
@@ -1 +1 @@
-{"ABACAVIR": 4.389003158639491, "ABRAXANE": 1.0378035890985686, "ACLASTA": 1.9094056560233803, "ADCIRCA": 1.612759556690386, "AFINITOR": 1.014283981741009, "ALDARA": 1.947444038755888, "ALL": 1.1187430934818905, "AMBRISENTAN": 1.004384308482322, "APIXABAN": 1.970971195248845, "ARAVA": 1.2741352298308095, "AUBAGIO": 1.37409057864488, "AVELUMAB": 1.3704133756629946, "AVONEX": 1.1956045101942148, "BAVENCIO": 1.65208654866347, "BENLYSTA": 1.0884007235859114, "BENRALIZUMAB": 1.0588515020218991, "BEXTRA": 1.937239186729625, "BINIMETINIB": 1.9121242959314009, "BONVIVA": 4.888974441123088, "BOSULIF": 1.1257710115661586, "BOTULINUM": 10.81923093934935, "BRUKINSA": 1.4089393263110053, "BUPIVACAINE": 3.996373404203416, "BYETTA": 1.27587573225797, "CABAZITAXEL": 1.509234558733672, "CABOTEGRAVIR": 1.77644870715828, "CAELYX": 4.11807273787603, "CANAGLIFLOZIN": 1.1605496592176716, "CELECOXIB": 1.1087861591401498, "CERVARIX": 1.6821739781961704, "CINACALCET": 1.1097844214853203, "COMIRNATY": 1.104761901839357, "CONTRAST": 1.457861795359886, "COSENTYX": 2.347618568762316, "COVID19": 1.7812400776305002, "CRIXIVAN": 1.6528518456675296, "DARZALEX": 1.1218629719304791, "DENOSUMAB": 4.515222883434026, "ELLAONE": 2.480527595472175, "ENTYVIO": 1.5566628730851717, "ENZALUTAMIDE": 1.6393863470033825, "ESMYA": 1.2191854346725612, "EVENITY": 1.2971214669419198, "EVISTA": 1.9927578367885923, "EXFORGE": 1.3293193106016803, "EXJADE": 1.0398209281996027, "FAMPYRA": 1.6786472824453629, "FASLODEX": 2.482875367776743, "FILGRASTIM": 1.3198934676047729, "FIRDAPSE": 1.9707529517727225, "FLEBOGAMMA": 9.682999541249233, "FORSTEO": 5.205701949766551, "FORXIGA": 1.8680553293508493, "FOTIVDA": 1.2409331870885345, "FULVESTRANT": 1.1338458891573235, "GARDASIL": 1.607687613693195, "GAZYVARO": 1.035277794827647, "GILENYA": 1.2490089847622043, "HEPSERA": 4.143619523804344, "HIZENTRA": 1.213655471141947, "HUMIRA": 1.7653620808038837, "HYDROCORTISONE": 1.624348282119747, "IBRANCE": 1.5255731871114009, "IDACIO": 1.2395321714951348, "INFERGEN": 1.7657424480974897, "IXIARO": 2.302881684585676, "JANUMET": 1.3421457830185866, "JANUVIA": 1.2315923346612494, "KENTERA": 1.8310119666233675, "KIOVIG": 3.731648370017065, "LEFLUNOMIDE": 1.3620455759863614, "LIBTAYO": 1.4266019384408215, "LUTETIUM": 1.2585017249535695, "LYRICA": 1.4805474455534926, "MARAVIROC": 4.099885419004326, "MEPOLIZUMAB": 1.1396167603234897, "MICARDIS": 1.279069823030321, "MICARDISPLUS": 1.026324296144705, "MIRCERA": 1.1756005793769717, "MOVYMIA": 4.878319875407518, "NEULASTA": 2.6227792385709163, "NINLARO": 1.9404315214170729, "NIVESTIM": 6.015607359172312, "NUCALA": 1.5910259139768623, "OCEAN": 6.007984708625272, "OCRELIZUMAB": 1.4463940794452284, "OCTREOTIDE": 1.5490871591037536, "OMALIZUMAB": 1.44750900827745, "ORENCIA": 2.4096132842581617, "PACLITAXEL": 1.1059028426575042, "PANITUMUMAB": 1.0069766336720376, "PEGFILGRASTIM": 1.4733072647902163, "PEGINTRON": 1.0731757056788884, "PIOGLITAZONE": 1.4059734266219668, "POMALIDOMIDE": 1.001057081902445, "PRIVIGEN": 2.6356742134845845, "PROLIA": 2.1297964786699315, "REKAMBYS": 3.942802078297676, "RELVAR": 1.7004228664173249, "REMSIMA": 1.814641418370886, "REPATHA": 2.934197525506811, "REVLIMID": 1.362412417901714, "RIBOCICLIB": 1.330382936285287, "RIXATHON": 1.595356606620108, "SHINGRIX": 1.126818426296687, "SOLIRIS": 1.0666332727992112, "SPIKEVAX": 1.0567394608046976, "SPINRAZA": 3.958708126764131, "SUTENT": 1.0832660143300097, "TEDUGLUTIDE": 3.826840705334224, "TERIFLUNOMIDE": 2.35408132758621, "TERIPARATIDE": 3.2535292471658583, "TERROSA": 4.502696978429284, "TORISEL": 1.924110468148449, "TOZINAMERAN": 1.695545139213567, "TRELEGY": 1.1233170424169283, "USTEKINUMAB": 1.1437057741357797, "VAXZEVRIA": 1.488996568462588, "VEDOLIZUMAB": 1.2381797752394932, "XELJANZ": 1.7852727018231611, "XGEVA": 2.935845632824664, "XOFIGO": 1.743525162513078, "XTANDI": 2.982876412686557, "ZARZIO": 13.621316334841092, "ZEJULA": 1.1246233606425804, "ZOMETA": 1.847306285300218, "ZOSTAVAX": 1.9927711732247708, "ZYCLARA": 1.0637067118090064}
\ No newline at end of file
+{"ABILIFY": 237.3728251579793, "ARIPIPRAZOLE": 447.8543929155082, "OLANZAPINE": 3.495175376216602, "null": 0.3652140691645825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8160.json
index bb85db5bb59..00eb5f3aa4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8160.json
@@ -1 +1 @@
-{"ABATACEPT": 1.2553377804857082, "AFINITOR": 1.107491622744066, "ARAVA": 8.292598575101, "AUBAGIO": 3.0701381657271045, "BENLYSTA": 6.479566247594257, "CIMZIA": 2.502074311756609, "COSENTYX": 1.5735708468229914, "CYMBALTA": 1.299412966103555, "CYTARABINE": 4.400446714301371, "ELIQUIS": 1.6189937330661053, "ENBREL": 1.947290557031504, "ENTYVIO": 3.043349478912547, "EVENITY": 6.41678709579727, "EXJADE": 1.6860059318495808, "FASLODEX": 4.251293909990223, "FORSTEO": 2.0423670135112846, "HIZENTRA": 4.314104281288132, "HUMIRA": 1.8472683948175583, "IBRANCE": 3.639243743902664, "LANTUS": 1.1981922748232068, "METHOTREXATE": 1.2619705883068677, "OFEV": 3.696739249755713, "OPSUMIT": 1.546905925613444, "OZEMPIC": 34.463100316907365, "PEGASYS": 2.2149747826574537, "PEGINTRON": 1.79732031395882, "RITUXIMAB": 5.137408110558667, "RUCONEST": 14.606423592705545, "SIMPONI": 11.580897009012087, "STELARA": 5.508861727600191, "SUTENT": 3.2701134605073365, "XELJANZ": 9.754547732061573, "ZOSTAVAX": 1.8291989136575992}
\ No newline at end of file
+{"COMIRNATY": 2.9376681416248616, "COSENTYX": 3.9937734129668514, "GARDASIL": 1.101212217472603, "HEXYON": 101.14428493815488, "INFANRIX": 43.20443839174434, "KEYTRUDA": 1.5575537076677863, "PEGASYS": 1.0927592228447758, "SPIKEVAX": 1.8992004965692637, "STELARA": 1.2419355819206597, "TWINRIX": 11.963244230239397, "VAXZEVRIA": 0.1869486565506996, "ZOSTAVAX": 3.170419996185801, "null": 0.6283566307574235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8161.json
index 89213a23a3d..fd07fdf7a69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8161.json
@@ -1 +1 @@
-{"ATRIPLA": 843.0683356298147, "TRUVADA": 1.697707203229981}
\ No newline at end of file
+{"null": 11.895720313561444}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8162.json
index ba7b11bee9d..188a75221bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8162.json
@@ -1 +1 @@
-{"ATRIPLA": 86.98250481022028, "BUPRENORPHINE": 1.4520417385284807, "GENVOYA": 1.075845529214493, "KALETRA": 4.52737054330724, "STRIBILD": 36.9627791881238, "TRUVADA": 42.11848744358908, "VIREAD": 12.845982061748348}
\ No newline at end of file
+{"ERLEADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8163.json
index c6444164cbe..1a4206c09e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8163.json
@@ -1 +1 @@
-{"ROTATEQ": 704.8909425198522, "null": 1.333208444257629}
\ No newline at end of file
+{"null": 0.9714101814927028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8164.json
index 7a15e5ceeb0..a91e82f682c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8164.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 18.393981687579338}
\ No newline at end of file
+{"null": 0.5962946423718517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8165.json
index da2e3eebe9f..9c53493c959 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8165.json
@@ -1 +1 @@
-{"AFINITOR": 1.060515797590456, "AIMOVIG": 1.98273721120358, "ANAKINRA": 3.795449975751888, "AUBAGIO": 2.6240898219093376, "BENLYSTA": 2.083339778994451, "BONVIVA": 6.53543194901932, "CHAMPIX": 1.4659229508440637, "COMIRNATY": 1.3231885730715975, "COSENTYX": 1.0291993087417608, "COVID19": 1.5433017997642788, "CYMBALTA": 1.168525773771375, "ELIQUIS": 1.1372018840040812, "ENBREL": 2.98839315604369, "ENTYVIO": 1.6586203002924398, "ETANERCEPT": 20.25336712824321, "FAMPYRA": 2.762628034169202, "FORSTEO": 2.873034675402179, "HUMAN": 1.810751864647832, "IBRANCE": 2.162672460436755, "IBUPROFEN": 1.430940789622298, "RINVOQ": 1.4181795263246113, "SIMPONI": 1.5058269082947864, "SPIKEVAX": 1.359351505207668, "STELARA": 1.4674119621047068, "SUBOXONE": 2.4500764260056265, "SUTENT": 2.256764396915057, "TOZINAMERAN": 1.6610836436640086, "TREMFYA": 2.585514586382922, "VAXZEVRIA": 1.6026530690025624, "VICTOZA": 1.4302902654033829, "XELJANZ": 1.9685653117513204}
\ No newline at end of file
+{"TOPOTECAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8166.json
index 2292edbdde4..567debdd56e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8166.json
@@ -1 +1 @@
-{"HYDROCORTISONE": 237.4904148028552, "PROTOPIC": 769.574491164585, "null": 4.724399646158816}
\ No newline at end of file
+{"CICLOSPORIN": 13.352969762331597, "JAKAVI": 82.90671046043676, "RINVOQ": 27.121008505975063, "XELJANZ": 5.985089444831888, "null": 0.2815437815428854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8167.json
index 7be8420a3f0..e0ff7a001e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8167.json
@@ -1 +1 @@
-{"ABACAVIR": 1.0157314753179925, "ABILIFY": 1.3310463531279015, "ATAZANAVIR": 4.298159269887615, "BENZODIAZEPINES": 36.4015154773553, "BRILIQUE": 1.2184866445913185, "COMBIVIR": 2.3804226744105392, "FENTANYL": 2.134454085751316, "IRBESARTAN": 11.290885564312942, "IVABRADINE": 14.452431858859548, "LEVETIRACETAM": 1.20266677007843, "LEVOFLOXACIN": 10.294226857991136, "MEXILETINE": 60.34591175080017, "MIDAZOLAM": 6.301394946101258, "MULTAQ": 13.64594892288073, "NOXAFIL": 5.670727954872186, "OLANZAPINE": 5.666907076393908, "OSIMERTINIB": 9.240178552416998, "POSACONAZOLE": 16.209239521131057, "PROPRANOLOL": 5.562997034987509, "RANEXA": 12.64698954549783, "RANOLAZINE": 19.51608325145857, "TAGRISSO": 2.3862463935662435, "TAMIFLU": 1.6090269801119383, "VFEND": 6.103977272232234, "VORICONAZOLE": 8.95837744414638, "null": 6.399700596818088}
\ No newline at end of file
+{"HUMIRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8168.json
index 3fb0f14e1a4..d1b972853b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8168.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 8.550532260448895, "COMIRNATY": 1.1385174837880068, "CYMBALTA": 1.068384254408486, "FIRDAPSE": 12.4754585950007, "GARDASIL": 1.1377554914819723, "LATUDA": 11.176071403279094, "OLANZAPINE": 11.14843886135258, "ZYPREXA": 4.791621878891849, "null": 1.7538147815582938}
\ No newline at end of file
+{"AFINITOR": 170.67376561554318, "BYETTA": 8.674153217862413, "EVEROLIMUS": 49.35720273574054, "LUTATHERA": 432.6586984026894, "SUTENT": 1.7483625507026512, "null": 0.6440651275177535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8169.json
index 7b9a914e041..9579eb403b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8169.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"AFINITOR": 117.58623992052208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/817.json
index 7174caf3ac7..fb219a5ea6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/817.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/817.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 11.823711518616143, "ANIDULAFUNGIN": 27.023867156305663, "APROVEL": 4.905619545794607, "ASPARAGINASE": 8.94642099772847, "AZACITIDINE": 23.173383842655763, "AZATHIOPRINE": 2.9763327062180025, "BEVACIZUMAB": 5.805863403967593, "BORTEZOMIB": 6.7030803846941245, "BUSULFAN": 25.7529876452356, "BYETTA": 1.574764113393327, "CAPECITABINE": 2.236781853131563, "CARMUSTINE": 11.825149944179778, "CASPOFUNGIN": 9.115324444665276, "CELLCEPT": 4.637697081020913, "CICLOSPORIN": 5.058912011796364, "CUBICIN": 12.68108146363558, "CYTARABINE": 13.95244220028158, "DEXAMETHASONE": 3.914875550691824, "DOCETAXEL": 2.677746635246708, "DOXORUBICIN": 10.1551895804153, "EVOLTRA": 66.97157870114837, "EXJADE": 3.442766723837226, "FIRDAPSE": 3.888690093487265, "FORXIGA": 1.490620158356636, "HUMAN": 3.035931942615503, "HYDROCORTISONE": 3.798089633585603, "INCIVO": 2.582092121152389, "IRINOTECAN": 3.018778767065414, "JAKAVI": 4.077083447590366, "JANUVIA": 1.4381260771873017, "JARDIANCE": 1.53029505945244, "KYMRIAH": 4.141837613329832, "LEVETIRACETAM": 1.173405357020642, "LEVOFLOXACIN": 3.442758052709024, "LONSURF": 3.005459280679409, "MELPHALAN": 11.243229974855714, "MEPOLIZUMAB": 1.5100285442308077, "MERCAPTOPURINE": 10.45845608051359, "METHOTREXATE": 2.8035165209913875, "MYCOPHENOLATE": 10.709392825571816, "NAGLAZYME": 4.12489650054704, "NPLATE": 3.389601660596536, "OPSUMIT": 3.0465467580142147, "OPTIMARK": 2.5540368463330205, "PEGASYS": 1.878375017045327, "PRIVIGEN": 7.2704653184229, "RITUXIMAB": 5.978353536446752, "ROACTEMRA": 2.070889258345577, "SOLIRIS": 11.145804522172426, "SPINRAZA": 3.8972613411075407, "TIGECYCLINE": 36.50545089236813, "TRACLEER": 1.6403713601916652, "VFEND": 2.203077559365195, "VOTRIENT": 1.124422420780631, "YESCARTA": 8.802988200883284}
\ No newline at end of file
+{"null": 3.671033077076547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8170.json
index 479150177d5..ad7d441e0b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8170.json
@@ -1 +1 @@
-{"null": 1.474794731145718}
\ No newline at end of file
+{"AFINITOR": 223.98435528804765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8171.json
index 18dc1736eb9..37f565f86fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8171.json
@@ -1 +1 @@
-{"SOLIRIS": 1002.0522991421444}
\ No newline at end of file
+{"null": 0.8145643285262828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8172.json
index 3d3424353cd..4a124daee88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8172.json
@@ -1 +1 @@
-{"SOLIRIS": 1159.028160661451}
\ No newline at end of file
+{"null": 1.159683279053483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8173.json
index 5d85c40e5ca..724838da989 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8173.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 348.9041624827356}
\ No newline at end of file
+{"AIMOVIG": 55.86680031881256, "null": 0.5517963774003628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8174.json
index 90cbca37f58..4abdd7ea39c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8174.json
@@ -1 +1 @@
-{"AVAMYS": 12.10264314939236, "BUDESONIDE": 26.15753927417377, "CYTARABINE": 7.008477902584493, "MEPOLIZUMAB": 27.465068316865075, "PEGASYS": 1.631693282132419, "null": 1.0254826868745777}
\ No newline at end of file
+{"PAZOPANIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8175.json
index 5c99da3eb74..44981e0418f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8175.json
@@ -1 +1 @@
-{"ACLIDINIUM": 1487.0384993080331, "ANORO": 60.45627678256857, "AVAMYS": 223.62474719659772, "GLYCOPYRRONIUM": 632.3955860102072, "NUCALA": 12.582571534263272, "OMALIZUMAB": 29.52169392153544}
\ No newline at end of file
+{"ARAVA": 0.5317952993357572, "AUBAGIO": 4.332997045852368, "COMIRNATY": 0.2176195673558833, "CYMBALTA": 1.4528619901091913, "GARDASIL": 4.093308835175206, "KEPPRA": 5.0551044729125065, "OCEAN": 768.5327563352045, "VAXZEVRIA": 0.157192298882261, "ZOSTAVAX": 3.13214489513645, "null": 1.5508436245091948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8176.json
index 77d27076794..0423d22712c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8176.json
@@ -1 +1 @@
-{"PREGABALIN": 31.937128994645622, "null": 3.597453321039998}
\ No newline at end of file
+{"null": 1.137551230252462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8177.json
index 6e9e6e54e22..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8177.json
@@ -1 +1 @@
-{"EYLEA": 29.81871117223606, "NEVANAC": 1116.2411709572875, "TOBRAMYCIN": 55.38051686224862, "null": 7.2211412869379314}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8178.json
index eec98125345..ebdb95d5e7e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8178.json
@@ -1 +1 @@
-{"BUSULFAN": 3.9563340857626166, "CANCIDAS": 9.512090790117238, "CELLCEPT": 1.5524429103803066, "CICLOSPORIN": 10.74354189057058, "CYTARABINE": 1.3694648757444217, "DEXAMETHASONE": 1.4820328892273764, "EMEND": 15.906703000170758, "FENTANYL": 1.2096612461266254, "KEPPRA": 3.4918725130635884, "LEVETIRACETAM": 3.5640887841101803, "LEVOFLOXACIN": 1.6370375776350343, "LYRICA": 2.218905308518178, "PREGABALIN": 3.913110704080435, "VFEND": 1.62842464698937, "null": 6.172087907267465}
\ No newline at end of file
+{"COMIRNATY": 0.6127729188419985, "TOZINAMERAN": 5.11213390974285, "VAXZEVRIA": 0.4521599186223275, "null": 0.9714101814927028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8179.json
index 3df0c03a809..05c1f1481df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8179.json
@@ -1 +1 @@
-{"1": 102.8388320701753, "ACTRAPID": 14.423900937408742, "ADENURIC": 2.740091497767901, "ALIMTA": 2.695801025604946, "AMIKACIN": 2.5171902050598183, "AP": 162.71917378687976, "APROVEL": 1.5705080771223916, "AZARGA": 188.7290780133875, "AZOPT": 146.66405515416187, "CAELYX": 2.360747061845563, "CANCIDAS": 17.44600546216288, "CASPOFUNGIN": 13.241548939717738, "CICATRIZANTS": 142.10352587642558, "CICLOSPORIN": 1.2147510643735353, "COMBIVIR": 1.5264097263377292, "COTELLIC": 2.310534855042937, "CUBICIN": 4.194768165959792, "CYTARABINE": 1.7603941629984672, "DAPTOMYCIN": 8.955312494502156, "DEXAMETHASONE": 3.3265093497102813, "DOCETAXEL": 1.028477344158184, "DOXORUBICIN": 1.5675494236052534, "EMEND": 32.75162207631664, "ENOXAPARIN": 4.01159651663125, "ERLEADA": 13.41073305438618, "ESOMEPRAZOLE": 3.1705875715707443, "EUGALAN": 1310.0945573625113, "FEBUXOSTAT": 6.188260503623746, "FENTANYL": 1.5073168163632906, "FILGRASTIM": 2.8568773211861616, "FYCOMPA": 5.53517838660358, "GLIBENCLAMIDE": 4.464358534980282, "HALAVEN": 1.889508775481776, "HUMAN": 2.589178816128908, "HYDROCORTISONE": 3.8657258517792914, "IBUPROFEN": 8.540315390374037, "IPILIMUMAB": 3.686371464834559, "IRESSA": 1.7911693345167456, "KEPPRA": 5.796241590630328, "KEYTRUDA": 3.443885010688703, "KIVEXA": 7.03745897433159, "KONTRASTMITTEL": 240.08497729088683, "LACOSAMIDE": 3.7998664101949, "LAMIVUDINE": 5.688526498137124, "LEVETIRACETAM": 6.027602506804378, "LEVOFLOXACIN": 6.668429993556349, "MABTHERA": 1.8795697030027203, "MANNITOL": 18.609102870062333, "NEVIRAPINE": 42.56978628869768, "NOT": 3.466140014766302, "OPDIVO": 2.503009088371614, "OSELTAMIVIR": 7.349449915721306, "PANTOPRAZOLE": 6.325751750610192, "PEMBROLIZUMAB": 5.781953473209828, "PEMETREXED": 3.070247010802734, "PLAVIX": 1.269125419803241, "POTELIGEO": 10.77964029755511, "PRADAXA": 3.1513804044082283, "PREGABALIN": 1.1510091781425331, "SIFROL": 3.383928282951689, "SPIRONOLACTONE": 2.25807257142071, "SUFENTANIL": 2.765564380201957, "TAMIFLU": 7.452641959325338, "TELMISARTAN": 2.0374826664606847, "TEMODAL": 4.9508593319439935, "TOBRAMYCIN": 8.230342361227871, "VEMURAFENIB": 8.0105525505254, "VFEND": 2.7803196286874434, "VIMPAT": 1.0759341058657952, "VIRAMUNE": 21.714389466617284, "VORICONAZOLE": 3.840935485416468, "ZELBORAF": 5.085962498058287, "null": 3.2390010841499235}
\ No newline at end of file
+{"SPIRONOLACTONE": 249.2446564928584, "null": 0.5020616532772642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/818.json
index 6dc8ed295a1..db7d77880c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/818.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/818.json
@@ -1 +1 @@
-{"BENRALIZUMAB": 1459.239819087143, "OCEAN": 1932.5772961263}
\ No newline at end of file
+{"ABILIFY": 3.857990757426293, "ARIPIPRAZOLE": 15.017038945774674, "IRON": 41.17781339224688, "OLANZAPINE": 19.26451697148086, "ZYPADHERA": 11.793153247741134, "ZYPREXA": 4.8880740623079, "null": 6.67428405499524}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8180.json
index a695b7ac9d5..1f6e3a14c8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8180.json
@@ -1 +1 @@
-{"null": 1.7609822260584742}
\ No newline at end of file
+{"ABILIFY": 15.218072004490958, "ARIPIPRAZOLE": 16.887384496208956, "ASENAPINE": 19.97782218049421, "BUDESONIDE": 0.6695268650805557, "CARBIDOPA": 14.658409852232866, "COMTAN": 17.09824342074636, "CYMBALTA": 1.0793438345627395, "DEXMEDETOMIDINE": 6.936658181368837, "DULOXETINE": 2.418524139041924, "ENTACAPONE": 19.767517285193183, "ESOMEPRAZOLE": 11.863418489686396, "FENTANYL": 1.6884644564418914, "HYDROCORTISONE": 1.001911707216251, "IBUPROFEN": 0.6506395754734045, "INVEGA": 21.885678113490577, "KEPPRA": 0.5952562193798314, "LATUDA": 11.85959994627396, "LEVODOPA": 17.41257569686684, "LEVOFLOXACIN": 0.4323209418233855, "LOXAPINE": 22.794503539131547, "LURASIDONE": 20.48484485657965, "MIDAZOLAM": 1.2873979745597484, "OLANZAPINE": 56.44045296254424, "PALIPERIDONE": 45.18296401804053, "PEGASYS": 0.1129195532579178, "PREGABALIN": 1.6209834364102378, "RISPERIDONE": 17.142879721773358, "STALEVO": 3.49465684394376, "SYCREST": 59.92183755876987, "XEPLION": 37.12060238203841, "ZYPADHERA": 4.160085951465657, "ZYPREXA": 43.50682076135289, "null": 2.768888622882957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8181.json
index d81961e0cf4..7c98cafe0c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8181.json
@@ -1 +1 @@
-{"null": 1.5053604204974995}
\ No newline at end of file
+{"ALISKIREN": 822.8640356071669, "COMIRNATY": 0.9078174016386714, "ELIQUIS": 3.096116742865502, "SPIKEVAX": 0.3457393246346687, "VAXZEVRIA": 0.3731813225852133, "null": 0.3654981050387228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8182.json
index 83618d56335..45c2ad6445a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8182.json
@@ -1 +1 @@
-{"null": 1.7702978896473245}
\ No newline at end of file
+{"CASPOFUNGIN": 22.90979267784319, "CICLOSPORIN": 5.567800959172347, "COMIRNATY": 0.0909591735310113, "CYTARABINE": 6.556559817281046, "KYMRIAH": 19.10260970130401, "LEVETIRACETAM": 9.669998720543736, "METHOTREXATE": 3.869357757511919, "SOLIRIS": 6.681689329903158, "VAXZEVRIA": 0.1330473056591771, "null": 1.1924774863701322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8183.json
index a1cb6207a5e..3c667e39fef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8183.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 71.25247674281823, "BEDAQUILINE": 201.1815642919925, "VORICONAZOLE": 98.11416738541432}
\ No newline at end of file
+{"COMIRNATY": 0.2121422379509969, "SPINRAZA": 194.5464689476435, "null": 0.9940555240062532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8184.json
index 47f72374a95..70c8349f1db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8184.json
@@ -1 +1 @@
-{"PEGASYS": 5.732189841457928, "null": 2.291196524396278}
\ No newline at end of file
+{"SPINRAZA": 1658.1405853221372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8185.json
index e042f74bbfb..cf2c7f45258 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8185.json
@@ -1 +1 @@
-{"ACTRAPID": 2.936809930335765, "ADENURIC": 3.766647909585721, "AERIUS": 3.860998897638804, "ALIMTA": 5.678609767375122, "AMIKACIN": 1.8981746198955416, "APROVEL": 2.158962104911723, "BIKTARVY": 2.094274620573904, "BRILIQUE": 2.7787082755835786, "BUSULFAN": 1.3309708305845689, "CAELYX": 7.479793148253372, "CANCIDAS": 19.13423348005566, "CASPOFUNGIN": 4.486098956338444, "CHAMPIX": 1.030902085830114, "CLADRIBINE": 4.775728324497839, "COAPROVEL": 8.024413850109012, "COBIMETINIB": 13.451074447133037, "COMBIVIR": 2.098781724794677, "COTELLIC": 17.50779306578391, "CUBICIN": 8.553486020549041, "DEXAMETHASONE": 1.5339523791066916, "ERLEADA": 3.77506470746466, "ESOMEPRAZOLE": 1.941253971903531, "EXVIERA": 3.302812569092926, "IBUPROFEN": 1.4066459831009162, "INCIVO": 13.5481835008529, "INTELENCE": 8.470208755337556, "ISENTRESS": 2.8747360995195352, "JANUVIA": 1.1976916326313416, "KALETRA": 2.725761162499714, "KEPPRA": 2.3288348507470675, "KEYTRUDA": 1.1483538345571414, "KISQALI": 1.930819293495376, "LEVOFLOXACIN": 1.5859625006329463, "LITAK": 80.85767479288174, "LYRICA": 1.2265561655815431, "MEKINIST": 1.5488729113473003, "MICARDIS": 3.1440399303818216, "NEXAVAR": 4.024337606158823, "NORVIR": 6.115183930949762, "NOT": 1.5913543348070742, "NOVONORM": 10.655662568813671, "NOXAFIL": 5.3662063533103606, "OLYSIO": 4.347186937978319, "OPDIVO": 1.6033970013566503, "PANTOPRAZOLE": 2.0691621885211884, "PEGASYS": 1.3254421336700672, "PEGINTERFERON": 3.906682617415401, "PEGINTRON": 2.357253317035293, "PEMBROLIZUMAB": 1.7622357890754434, "PLAVIX": 2.7612730998833723, "PRIVIGEN": 3.270143808704567, "PROTELOS": 18.457914364249497, "REVLIMID": 2.410586752466516, "RIBAVIRIN": 1.643418717645757, "STIVARGA": 2.683455399512715, "STOCRIN": 23.007443378207885, "SUFENTANIL": 5.716324515093811, "TAGRISSO": 1.5019381101722589, "TAMIFLU": 1.645354084840361, "TEMODAL": 5.32718600065986, "THALIDOMIDE": 3.851538552788668, "VFEND": 1.870835923935776, "VIMPAT": 1.3220014999725536, "XARELTO": 1.2348292914444678, "ZELBORAF": 5.339208258861574, "null": 2.766928412793941}
\ No newline at end of file
+{"ABACAVIR": 2.1239278787773963, "AIMOVIG": 0.8089468941563115, "ANORO": 136.9654211957681, "APIXABAN": 18.54328183073488, "ARAVA": 0.1469658699083839, "AZATHIOPRINE": 8.176051352920183, "CAELYX": 3.571900301581749, "CICLOSPORIN": 1.9673843447476167, "CLOPIDOGREL": 0.9322771682810492, "COMIRNATY": 0.8242822684318254, "CYMBALTA": 0.7299467557962891, "GARDASIL": 2.9425877240799285, "KEPPRA": 0.6123187149801045, "KEYTRUDA": 1.0236886009407449, "OLANZAPINE": 1.105406228071568, "PEGASYS": 0.5688311201492194, "PLAVIX": 0.6585351978788316, "ROTASHIELD": 123.43464368199488, "SHINGRIX": 1.458999174237421, "SOLIRIS": 1.407793428198925, "SPIKEVAX": 0.7486748419098395, "SUTENT": 0.2192563880504053, "TAMIFLU": 2.036530638883425, "TOZINAMERAN": 1.918850447018612, "VAXZEVRIA": 0.6971208629344309, "VFEND": 1.4570746994045531, "YESCARTA": 3.932976493530116, "ZYPREXA": 0.6555657581902252, "null": 0.7894933207463578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8186.json
index 03ccf0f94ac..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8186.json
@@ -1 +1 @@
-{"ABILIFY": 4.5175373092797, "ACE": 2.517962398323903, "ALL": 3.397317101549877, "ALPELISIB": 1.738763597777095, "ALPHA": 84.87282914211947, "AMBROXOL": 18.03602615306352, "AMIKACIN": 1.6034807458760816, "AMLODIPINE": 16.72914899626805, "ANGIOTENSIN": 16.31705215644659, "ANGIOTENSINCONVERTING": 30.657637203995407, "ANTACIDS": 87.93454386707116, "ANTICHOLINERGIC": 34.113043035237474, "ANTIDEPRESSANT": 16.618445591439382, "ARIPIPRAZOLE": 7.685911246360181, "ASENAPINE": 24.842176364235915, "BARBITURATES": 38.30106442042462, "BASILIXIMAB": 1.3159819378870283, "BENZODIAZEPINE": 26.654608788681, "BENZODIAZEPINES": 6.998741173808761, "BETA": 26.78575417321673, "BEVACIZUMAB": 1.8916702310921665, "BEXTRA": 1.7649981429866954, "BRIMONIDINE": 3.4608334187773164, "BUMETANIDE": 9.163239687410714, "BUPRENORPHINE": 9.790995253756844, "BUVIDAL": 5.651454062519102, "CAFFEINE": 10.85850513254288, "CALCIUM": 28.557720540389333, "CANAGLIFLOZIN": 1.676778952496582, "CANNABINOIDS": 16.95599428910996, "CAPECITABINE": 1.437323538377746, "CARDIAC": 55.85553523051466, "CARIPRAZINE": 5.09512858683184, "CARMUSTINE": 1.599050526948328, "CELECOXIB": 3.122081017510918, "CETUXIMAB": 1.0234344769699124, "CICLOSPORIN": 1.520865578074438, "CLADRIBINE": 1.0301445910919624, "COBIMETINIB": 1.8248745570393168, "CYTARABINE": 1.0631785414525248, "DABRAFENIB": 1.0049808928359316, "DAPAGLIFLOZIN": 1.071560961810485, "DARUNAVIR": 1.262170651552334, "DASATINIB": 2.471776528658698, "DESLORATADINE": 1.253032247265889, "DEXMEDETOMIDINE": 2.264310416950857, "DIPHENHYDRAMINE": 35.05229652468624, "DIURETICS": 8.95414886981355, "DRUG": 8.289080547920074, "DULOXETINE": 17.477344576080725, "ESOMEPRAZOLE": 3.2299977469305428, "EVEROLIMUS": 1.4271438578243507, "FENTANYL": 16.303377521993667, "GLIBENCLAMIDE": 7.289764147767682, "GLUCAGON": 4.284395064895399, "GUANFACINE": 5.460121416690418, "HYDROCHLOROTHIAZIDE": 3.388301594537451, "IBRUTINIB": 1.239719542140084, "IBUPROFEN": 12.278529284242463, "ILLICIT": 119.73032131122972, "INTELENCE": 1.1779768536529096, "INVEGA": 1.9619899349981136, "IRBESARTAN": 1.846614286570018, "IRINOTECAN": 1.3352388860580526, "IRON": 4.852392448295709, "KALETRA": 1.0902784708831623, "LACOSAMIDE": 3.667838127629629, "LEVETIRACETAM": 2.8515691580952884, "LEVOFLOXACIN": 5.370332413921644, "LINACLOTIDE": 26.95828309183875, "LOPINAVIR": 1.689385511120565, "LOXAPINE": 6.251686584021923, "LURASIDONE": 8.60669550186828, "LYRICA": 1.807414954898085, "MANNITOL": 1.117257624773072, "MELATONIN": 3.515408352386807, "MELPHALAN": 1.2213336160568704, "MEMANTINE": 1.021413276990165, "MERCAPTOPURINE": 1.4863119517843826, "METHOTREXATE": 1.181230482094269, "MIDAZOLAM": 4.682827189843585, "MUSCLE": 31.393186735098087, "NALOXONE": 14.069781061849614, "NEVIRAPINE": 1.0585954913081028, "NOT": 3.802238221195037, "OFATUMUMAB": 3.286302126994183, "OLANZAPINE": 8.097498045037192, "OLAPARIB": 1.0362877291489745, "OPIOID": 19.32159908955936, "OPIOIDS": 11.557335086071468, "OXYBUTYNIN": 4.518411269372976, "PALIPERIDONE": 8.912159776758319, "PANTOPRAZOLE": 1.7201026437450415, "PAZOPANIB": 1.15757720331662, "PEMBROLIZUMAB": 1.423211510417322, "PEMETREXED": 1.32363846440682, "PIOGLITAZONE": 3.657993130570947, "POPPERS": 3.022339210321896, "POSACONAZOLE": 1.6567878588098872, "PRADAXA": 1.349691510499129, "PREGABALIN": 20.894681179740235, "PROPRANOLOL": 5.724654221004366, "QARZIBA": 2.0772291995017844, "REPAGLINIDE": 1.703946821084553, "RISPERIDONE": 7.321933732415831, "RITONAVIR": 1.7027323522275688, "RIVAROXABAN": 8.797043638871614, "SILDENAFIL": 2.624526114735678, "SITAGLIPTIN": 5.338830471858231, "SKELETAL": 89.14388211807089, "SODIUM": 19.5116998130631, "SORAFENIB": 1.2638936021967937, "SPIRONOLACTONE": 1.2572002583435242, "SUBOXONE": 4.15242501818528, "SUNITINIB": 1.419689146649728, "TACROLIMUS": 4.897400962091449, "TADALAFIL": 3.4816910427180288, "TELMISARTAN": 2.565865072581975, "TEMOZOLOMIDE": 2.4373725895555034, "TOBRAMYCIN": 1.531303030844077, "TRICYCLIC": 24.975687897462016, "UNKNOWN": 10.683844269619724, "UNSPECIFIED": 2.748323064287948, "VARENICLINE": 1.2008614818138652, "VIGABATRIN": 6.297140798308555, "VORICONAZOLE": 1.3956876910560618, "VORTIOXETINE": 2.607143829292662, "ZALEPLON": 16.427490773455173, "ZONISAMIDE": 2.055609582391482, "ZYPREXA": 2.044255622616792, "null": 4.170444836927049}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8187.json
index fb6e6a3399a..04b7e0c938e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8187.json
@@ -1 +1 @@
-{"FENTANYL": 16.334726387681624, "null": 5.890579729766149}
\ No newline at end of file
+{"null": 1.1619192809764267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8188.json
index bf613bb04c7..4d33918765c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8188.json
@@ -1 +1 @@
-{"ABACAVIR": 6.091908032087636, "BUSULFAN": 62.79826536846847, "CELLCEPT": 20.368267377088618, "CICLOSPORIN": 16.46679768892643, "KALETRA": 16.600565210882344}
\ No newline at end of file
+{"BRIDION": 287.7340574132472, "FENTANYL": 37.992009511524245, "SUGAMMADEX": 783.3574580078387, "null": 4.387480697097584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8189.json
index ac4a2490d5f..1edcf1a10ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8189.json
@@ -1 +1 @@
-{"null": 1.1894899744046088}
\ No newline at end of file
+{"FENTANYL": 14.293991890233958, "SUFENTANIL": 151.23454294364646, "SUGAMMADEX": 1233.7163544188072, "null": 3.4432675290038954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/819.json
index 4eecc6ea41b..4fdbb3bd243 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/819.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/819.json
@@ -1 +1 @@
-{"EYLEA": 485.90432951033193, "MVASI": 3913.820333543581}
\ No newline at end of file
+{"OLANZAPINE": 8.958374299271883, "null": 4.738605447153186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8190.json
index eb3aafdad82..71514b7a2e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8190.json
@@ -1 +1 @@
-{"null": 6.8031563798956105}
\ No newline at end of file
+{"null": 15.57967927764159}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8191.json
index 6012d08c40b..acb7c6034b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8191.json
@@ -1 +1 @@
-{"null": 1.275640031272104}
\ No newline at end of file
+{"COMIRNATY": 2.209372578930738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8192.json
index 1d7cd2013fd..07648dacfbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8192.json
@@ -1 +1 @@
-{"LENVIMA": 526.8247248548116}
\ No newline at end of file
+{"SPINRAZA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8193.json
index eaefb810cb6..ae430a0af3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8193.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 19.196020756998227, "NEXAVAR": 13.416407925936026}
\ No newline at end of file
+{"null": 1.816467044620977}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8194.json
index 1ba8e336552..95f9599f1c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8194.json
@@ -1 +1 @@
-{"COMIRNATY": 1.004794319649046, "null": 1.1927577248925028}
\ No newline at end of file
+{"BETAFERON": 36.07455045600889, "COMIRNATY": 1.1807677189387684, "GARDASIL": 5.663523013688188, "ROACTEMRA": 10.63931639279414, "SOLIRIS": 43.26446860664242, "SPIKEVAX": 0.7621529508558764, "TOZINAMERAN": 1.3790271413862696, "VAXZEVRIA": 0.6900033062876152, "null": 0.3626107516187079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8195.json
index ff9a9ba3187..295321a30ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8195.json
@@ -1 +1 @@
-{"null": 1.8332981225229688}
\ No newline at end of file
+{"COMIRNATY": 0.301927566285301, "GARDASIL": 2.4396592543916027, "KEYTRUDA": 2.317896217044717, "LEVETIRACETAM": 19.54209077248775, "null": 2.2793291968784226}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8196.json
index a9dfc746e97..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8196.json
@@ -1 +1 @@
-{"null": 2.329282992563667}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8197.json
index 28777a6e8c4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8197.json
@@ -1 +1 @@
-{"null": 3.3437678202669416}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8198.json
index 855c0a3db81..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8198.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1268133451570357, "SPIKEVAX": 1.5163376475234502}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8199.json
index 3b89ab0b0c4..0ce3f2156c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8199.json
@@ -1 +1 @@
-{"null": 1.400538092550131}
\ No newline at end of file
+{"HUMALOG": 41.50384132877456, "LANTUS": 7.403753378594509, "OPTIMARK": 19.30969205579556, "null": 0.5273758391628893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/82.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/82.json
index e77982df0d4..e1f7a4babcc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/82.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/82.json
@@ -1 +1 @@
-{"ABILIFY": 4.318415133287264, "BRINTELLIX": 7.461937364148074, "CHAMPIX": 2.200870636577734, "CYMBALTA": 1.2342064552191907, "QARZIBA": 114.14679605699676, "null": 3.049082258947944}
\ No newline at end of file
+{"CICLOSPORIN": 11.712332878803538, "JANUMET": 16.12786421658691, "null": 0.5415329271609199}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/820.json
index 9d465e5d363..9b685cf4542 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/820.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/820.json
@@ -1 +1 @@
-{"ACLIDINIUM": 4.561052833094216, "ALEMTUZUMAB": 2.1116822650164377, "AMIKACIN": 4.606451117559942, "APIXABAN": 1.1245180303037705, "ARANESP": 77.4887290005829, "ASPARAGINASE": 54.875844041382486, "AZATHIOPRINE": 1.3545086104832569, "BEDAQUILINE": 2.000699151960752, "BENLYSTA": 2.736413516238663, "BEVACIZUMAB": 1.053848410140496, "BUDESONIDE": 1.905141768255284, "BUSULFAN": 5.941789298979464, "CANCIDAS": 9.865618960501134, "CARMUSTINE": 9.056731761608964, "CELLCEPT": 2.689296534430722, "CICLOSPORIN": 6.485995642795644, "CRIXIVAN": 3.544951371030247, "CUBICIN": 2.224147029965766, "CYTARABINE": 11.848162457428147, "DARBEPOETIN": 53.175941204490975, "DASATINIB": 8.000523460831253, "DEXAMETHASONE": 2.78245281216752, "EXJADE": 2.610407809077524, "FILGRASTIM": 5.667570815093459, "FORXIGA": 1.0929955738245598, "HIZENTRA": 3.2044479059391437, "HUMAN": 1.7569399750363035, "HUMIRA": 1.1502528450121694, "IBRANCE": 1.5176813836231875, "INSULIN": 2.271366675830864, "JARDIANCE": 1.098210223729584, "KALETRA": 1.0069740454108014, "KYMRIAH": 1.884906598021698, "MELATONIN": 5.725215964894002, "MEPOLIZUMAB": 8.887497859691383, "METHOTREXATE": 2.366458461609237, "MYCOPHENOLATE": 4.753356925718961, "NOT": 2.682976584492553, "NUCALA": 1.1512975967391947, "OPSUMIT": 1.6289293806976008, "ORKAMBI": 4.663154745259368, "PEGINTRON": 1.1845052572920045, "PREGABALIN": 3.166634537611632, "RINVOQ": 1.2420653113053477, "RITUXIMAB": 2.089840712621517, "ROACTEMRA": 1.2436814389333524, "SIMPONI": 1.810600458803287, "SOLIRIS": 2.1304357343552662, "SPRYCEL": 1.3271437019618353, "SUTENT": 1.1782489563435528, "SYNAGIS": 2.467701493472656, "TACROLIMUS": 4.539085156493998, "TRELEGY": 2.511012727946337, "VFEND": 2.1349486394030004, "XELJANZ": 2.4603310213299525, "XOLAIR": 1.7290903623240683, "ZOSTAVAX": 1.9940083350378608}
\ No newline at end of file
+{"null": 1.9094105922474416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8200.json
index ff91a4353f3..3ef11e9d382 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8200.json
@@ -1 +1 @@
-{"BLINATUMOMAB": 144.28751527791215, "SYNAGIS": 36.95692845609894, "null": 1.18351156211745}
\ No newline at end of file
+{"null": 0.7816763579197556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8201.json
index 411a45e4273..186d03f9217 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8201.json
@@ -1 +1 @@
-{"AZTREONAM": 751.2570500801398, "null": 1.680176968009634}
\ No newline at end of file
+{"ABACAVIR": 0.9035426018366144, "ABASAGLAR": 0.8116761619176105, "ABEMACICLIB": 3.653065222941838, "ABILIFY": 0.0947538040347172, "ABRAXANE": 8.785004301437997, "ACLASTA": 3.266985132990228, "ACTOS": 1.6522419717469168, "ADALIMUMAB": 0.0445704456125108, "ADCETRIS": 59.3369447767476, "ADEMPAS": 0.9547408538354644, "AFINITOR": 0.6267858983402143, "AFLIBERCEPT": 3.3651431710500805, "AIMOVIG": 0.5764989904034432, "ALIMTA": 1.159816457828348, "ALPELISIB": 1.745242640891854, "AMIKACIN": 2.560224146769581, "AMINOSALICYLIC": 5.421332685387593, "APIDRA": 0.9107344492234184, "APREPITANT": 0.447429669381638, "APROVEL": 0.4429964839036669, "ARANESP": 0.3871629899826664, "ARAVA": 0.3858634088772694, "ARIPIPRAZOLE": 1.3943444162453416, "ASPARAGINASE": 1.704622472712535, "ATAZANAVIR": 0.6089192454873752, "ATEZOLIZUMAB": 3.158432318365032, "ATRIPLA": 0.280868630757933, "AUBAGIO": 4.482843728233076, "AVANDIA": 0.4437139646219206, "AVASTIN": 12.005233180159395, "AVONEX": 4.915939352194024, "AXITINIB": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8202.json
index 486f0d72deb..0e989848081 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8202.json
@@ -1 +1 @@
-{"IBUPROFEN": 25.983639904427555}
\ No newline at end of file
+{"BIKTARVY": 118.46683606821615, "null": 0.6943412800430605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8203.json
index 12878d878f9..3bb74d46d92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8203.json
@@ -1 +1 @@
-{"null": 2.992703786062721}
\ No newline at end of file
+{"EFAVIRENZ": 24.485149034334952, "EMTRICITABINE": 103.25528014840788, "LEVETIRACETAM": 7.691601974956101, "null": 6.352664352110819}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8204.json
index d83c79f5042..71b793d5a90 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8204.json
@@ -1 +1 @@
-{"AVAMYS": 46.57433352542154, "NAGLAZYME": 95.33772042909148, "NUCALA": 17.997598113826598, "null": 1.6339912665451757}
\ No newline at end of file
+{"INLYTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8205.json
index 3fe5404832e..88246c411d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8205.json
@@ -1 +1 @@
-{"ELIQUIS": 1.8759642962704548, "NAGLAZYME": 78.00385813281233, "SPINRAZA": 23.75630104692188, "TRACLEER": 17.597883895440866, "null": 1.2074553995396842}
\ No newline at end of file
+{"COMIRNATY": 0.6169199715449604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8206.json
index 9abb6c2c55e..f8189bc7dc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8206.json
@@ -1 +1 @@
-{"NAGLAZYME": 269.09333044475574, "SPINRAZA": 263.044119806319}
\ No newline at end of file
+{"COMIRNATY": 1.902653502238972, "MEPOLIZUMAB": 31.60168348045309, "null": 0.9862557608821318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8207.json
index cec7403c54a..de125b14cd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8207.json
@@ -1 +1 @@
-{"null": 1.8757787968757669}
\ No newline at end of file
+{"BUPRENORPHINE": 10.263710229728014, "CHAMPIX": 4.857320177532466, "COMIRNATY": 0.1881269807670656, "COMTAN": 66.36416249117842, "PEGINTRON": 11.744435572666768, "null": 1.7783349276905436}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8208.json
index 17b475883ea..f672a5e8dce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8208.json
@@ -1 +1 @@
-{"CIMZIA": 6.795047946597921, "DEXAMETHASONE": 11.42676618840779}
\ No newline at end of file
+{"null": 0.5949804266474418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8209.json
index f5039f45fcb..1f57d163d6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8209.json
@@ -1 +1 @@
-{"null": 1.3950246367703545}
\ No newline at end of file
+{"ABACAVIR": 0.8850979132007137, "ALIMTA": 1.026155911564335, "ARIPIPRAZOLE": 1.8585725593760472, "ASPARAGINASE": 14.2011200632041, "ATRIPLA": 0.1856587356367695, "AVASTIN": 11.784830169993056, "AXICABTAGENE": 96.237660765208, "BEVACIZUMAB": 20.188306238881456, "BLINATUMOMAB": 14.123888559518909, "BORTEZOMIB": 5.8134152823756295, "BREYANZI": 107.81329337021144, "BUPIVACAINE": 4.581303076470617, "BUPRENORPHINE": 1.0557542101425643, "BUSILVEX": 12.943401651148482, "BUSULFAN": 6.260510453593892, "CAELYX": 2.080584492222345, "CAPECITABINE": 12.0698877284344, "CETUXIMAB": 8.372217811797878, "CICLOSPORIN": 7.160951517709614, "COLISTIMETHATE": 38.40526030714968, "CYTARABINE": 5.400012623858544, "DESCOVY": 8.714819067114021, "DEXAMETHASONE": 2.208944184804886, "DOCETAXEL": 4.226472316353257, "DOXORUBICIN": 1.6868859354553865, "DULOXETINE": 1.6679422291061092, "EFAVIRENZ": 2.437111596279093, "EMTRIVA": 24.573582278336744, "FAMPRIDINE": 15.890887142486475, "FENTANYL": 2.234914140508974, "FILGRASTIM": 4.538518941240761, "HALAVEN": 6.94467427494983, "HERCEPTIN": 1.6116032091734411, "IMATINIB": 4.374529189614153, "INTELENCE": 19.471394046635037, "IRINOTECAN": 16.671000465264665, "ISENTRESS": 3.294920246030708, "JEVTANA": 3.971893911862381, "KEYTRUDA": 0.564186657524974, "KYMRIAH": 66.64143421379781, "LACOSAMIDE": 14.167596075578876, "LEVETIRACETAM": 1.5504386095296527, "LEVOFLOXACIN": 0.8707952722772382, "MABTHERA": 2.570163794905357, "METHOTREXATE": 2.3123199594692885, "MIDAZOLAM": 1.5284157880263856, "NEULASTA": 1.2163540358842158, "NOXAFIL": 6.764302951957865, "OLANZAPINE": 1.4347346033646349, "PACLITAXEL": 4.980259111635566, "PANITUMUMAB": 29.940356339272107, "POSACONAZOLE": 15.0974259307694, "RISPERIDONE": 4.223653893050045, "TACROLIMUS": 11.378608573956864, "THALIDOMIDE": 4.854351083876428, "THIOTEPA": 10.093362038127054, "TISAGENLECLEUCEL": 33.45867697076864, "TIVICAY": 23.15917344924086, "VECTIBIX": 23.748500805987835, "VFEND": 2.245860206919485, "VORICONAZOLE": 12.809669691928049, "XELODA": 7.1808520378960266, "YESCARTA": 343.4460247622447, "null": 1.5199356666375077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/821.json
index 0dd3aa03d98..968d27e78d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/821.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/821.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 18.61122825673286, "ASPARAGINASE": 9.318117569831845, "BORTEZOMIB": 13.62871952846341, "BUSILVEX": 83.33242876119397, "BUSULFAN": 25.124643237476256, "CELLCEPT": 6.091410745386403, "CICLOSPORIN": 6.363071184267494, "CYTARABINE": 14.25766666869462, "DEXAMETHASONE": 4.269094541303519, "HUMALOG": 1.214768143383843, "JARDIANCE": 1.5894995348332153, "MYCOPHENOLATE": 14.400579843309377, "PEGASYS": 1.088625842810568, "PEGINTRON": 2.7708975411929413, "RITUXIMAB": 5.157489484408598, "ROACTEMRA": 4.0289742310772665, "SOLIRIS": 6.543925587176647, "VFEND": 3.953155004341159, "null": 1.0782251601732844}
\ No newline at end of file
+{"COMIRNATY": 1.7082659128496316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8210.json
index 9975c59c985..51bc152a96f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8210.json
@@ -1 +1 @@
-{"ADENURIC": 3.5150908868305195, "AERIUS": 1.3514193543657291, "AFINITOR": 1.0486130387271635, "ALIMTA": 3.0260800569235307, "AMIKACIN": 3.188704852199632, "APROVEL": 1.6647100564380244, "ARIXTRA": 4.31299370868001, "AUBAGIO": 2.842578766578991, "AVELUMAB": 2.92623304726028, "AXITINIB": 6.058471708250701, "AZATHIOPRINE": 1.9753787371058031, "BARACLUDE": 5.250339805973239, "BEDAQUILINE": 3.1775667694290477, "BETAFERON": 3.9777790598302936, "BEVACIZUMAB": 1.279814595577269, "BIKTARVY": 1.986392682271735, "BOSULIF": 2.022107255253692, "BRILIQUE": 1.8509782991112889, "CABOMETYX": 1.92493780557757, "CAELYX": 2.8789548406255934, "CANCIDAS": 5.5955777393867, "CAPECITABINE": 1.0851515391019622, "CASPOFUNGIN": 4.1333777356422585, "CEFTAROLINE": 46.20561549648564, "CELECOXIB": 1.237945540168805, "CELLCEPT": 1.260888012859922, "CICLOSPORIN": 1.583165103349643, "CLOFARABINE": 3.7368416377832654, "COAPROVEL": 1.9499017990008525, "COBIMETINIB": 4.707810596005276, "COMBIVIR": 2.4845407021183474, 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"ZYPREXA": 2.405450244904582, "null": 1.654446835895527}
\ No newline at end of file
+{"null": 2.2199386146356224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8211.json
index ce5b2158267..49875581a93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8211.json
@@ -1 +1 @@
-{"null": 1.8656671978897164}
\ No newline at end of file
+{"ZOSTAVAX": 106.37552772585263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8212.json
index 1bc5511d7bd..aeb0d74bbde 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8212.json
@@ -1 +1 @@
-{"null": 2.2160764821872454}
\ No newline at end of file
+{"ARANESP": 38.10813106208835, "EPOETIN": 361.4433936119351, "null": 2.8367536692258013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8213.json
index 7438fb43320..04d3ef482b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8213.json
@@ -1 +1 @@
-{"JAKAVI": 418.244021212654, "KYMRIAH": 77.33313869724412}
\ No newline at end of file
+{"ABACAVIR": 0.169359151828357, "ABATACEPT": 0.0515702991104027, "ABEMACICLIB": 4.333085332063307, "ABILIFY": 0.6444320087815775, "ABRAXANE": 3.591824914948494, "ACCOFIL": 15.907607669357516, "ADALIMUMAB": 0.0259125423295115, "ADCETRIS": 16.77712565107658, "ADENURIC": 0.5119293322616705, "ADVAGRAF": 4.755111375175452, "AERIUS": 0.4311359073950936, "AFINITOR": 0.995802151321005, "AFLIBERCEPT": 6.855551668913844, "ALDARA": 0.8471777578191434, "ALEMTUZUMAB": 2.7291147392145367, "ALIMTA": 8.53182591618638, "ALOXI": 2.1648226549101324, "ALPELISIB": 1.0212059279637504, "ALYMSYS": 25.442439393492062, "AMIKACIN": 1.0327458362616748, "AMINOSALICYLIC": 0.0811630067720243, "ANAKINRA": 0.095333747937902, "ANIDULAFUNGIN": 8.282841627377136, "APREPITANT": 0.2339996642812061, "APROVEL": 1.0957517908435113, "ARANESP": 0.1633790580921471, "ARAVA": 0.2717564677725518, "ARIPIPRAZOLE": 2.401621232369953, "ARIXTRA": 1.1932809996531537, "ARZERRA": 6.518417060985879, "ASPARAGINASE": 4.752011931627049, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8214.json
index 528a7ff91d3..e14c3d15111 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8214.json
@@ -1 +1 @@
-{"ABILIFY": 3.281012722375777, "ADCIRCA": 5.3137371965168825, "ADEMPAS": 7.489274457862896, "AMBRISENTAN": 10.481514586680497, "ARANESP": 14.3272725313101, "BENLYSTA": 1.6123201651151948, "CLOPIDOGREL": 2.2015660794345746, "DARZALEX": 3.9783031878922097, "ELIQUIS": 21.28666246514373, "EPOETIN": 24.32321647747281, "EXJADE": 1.9515997100198823, "INCIVO": 3.2554820930583794, "IPILIMUMAB": 2.311058722106648, "JANUVIA": 1.139058975813834, "KEYTRUDA": 2.2354890584980778, "LONSURF": 11.417484940528787, "NEULASTA": 9.371017235375414, "OPSUMIT": 33.65957397209331, "PEGASYS": 8.967226893388936, "PEGINTERFERON": 10.60633124393717, "PEGINTRON": 20.685621712119307, "PLAVIX": 1.2507340341111302, "RIBAVIRIN": 6.069081172467718, "ROTATEQ": 2.1698440744487995, "RUBRACA": 9.138928960232992, "SOLIRIS": 16.60125081570065, "SPRYCEL": 8.59006720776718, "TRACLEER": 17.948926901163937, "VELTASSA": 5.369868749684438, "VOTRIENT": 2.1073581788693665, "XOFIGO": 5.448950213336653, "XTANDI": 1.7134127590420627}
\ No newline at end of file
+{"ARIPIPRAZOLE": 315.01984304075387, "REMICADE": 151.82492576238687, "null": 0.5493432248751642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8215.json
index dddef8e2b48..33d3b8e987c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8215.json
@@ -1 +1 @@
-{"ARANESP": 25.49812255368961, "EXJADE": 17.444916406238743, "HUMIRA": 27.951435803193966, "PRIVIGEN": 78.3204035106524, "SOLIRIS": 20.802075077006705, "null": 1.0300434994485894}
\ No newline at end of file
+{"ASPARAGINASE": 35.58110644337845, "AZACITIDINE": 31.263827805238563, "BUSULFAN": 16.344648437392422, "CLADRIBINE": 98.39650481119038, "CYTARABINE": 30.74581354202947, "DEXAMETHASONE": 13.066952859811042, "DOCETAXEL": 23.714571167964287, "IRINOTECAN": 18.1347637326855, "MELPHALAN": 60.461402812124255, "NOXAFIL": 39.42474232419959, "PEMETREXED": 26.199465956507265, "TRODELVY": 264.3894184690821, "null": 0.5521137127573341}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8216.json
index f6b14531390..7e13b730498 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8216.json
@@ -1 +1 @@
-{"PRIVIGEN": 251.85200613890905, "null": 1.659913266071359}
\ No newline at end of file
+{"CYTARABINE": 68.21820345943779, "JEVTANA": 65.4639443293483, "RITUXIMAB": 17.65454072939461, "null": 0.2160720495467954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8217.json
index edc6f333856..074bf6f8e26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8217.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8217.json
@@ -1 +1 @@
-{"FLEBOGAMMA": 132.70451860679563, "HUMAN": 196.10301491211683, "PRIVIGEN": 120.33302668953164, "null": 1.4100520275614696}
\ No newline at end of file
+{"ALIMTA": 13.71526175504257, "ASPARAGINASE": 11.001427394410594, "ATEZOLIZUMAB": 42.49001034979912, "AVASTIN": 3.3375598598567167, "AZACITIDINE": 38.46956013909756, "BEVACIZUMAB": 5.823790598247084, "BLINATUMOMAB": 32.165819567441254, "CAELYX": 9.34679140187509, "CARMUSTINE": 42.005298328183, "CICLOSPORIN": 0.8347465948602151, "CYTARABINE": 21.44495738479297, "DEXAMETHASONE": 15.514025115168238, "DOCETAXEL": 7.721431403401235, "DOXORUBICIN": 18.021746827221516, "FILGRASTIM": 19.917272888526316, "GAZYVARO": 16.682693453617606, "HALAVEN": 14.272453684068877, "IBRANCE": 1.7440102869659468, "IRINOTECAN": 7.592136953590644, "JEVTANA": 12.716553873488872, "KEYTRUDA": 0.6686605946049237, "METHOTREXATE": 7.467014748638735, "NEULASTA": 52.52440530302146, "OBINUTUZUMAB": 26.11896152102213, "PEMBROLIZUMAB": 4.578492528267693, "PEMETREXED": 15.810092617644823, "RITUXIMAB": 22.854764685889563, "TRODELVY": 34.953182777898256, "VENETOCLAX": 14.671156167849382, "VYXEOS": 138.48004694764285, "YONDELIS": 40.93582995344361, "null": 0.7825753095083715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8218.json
index b830ab1f07f..a8268817ed0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8218.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8218.json
@@ -1 +1 @@
-{"HUMAN": 231.92152943682197, "PRIVIGEN": 97.09580515036446, "null": 1.0336706000776814}
\ No newline at end of file
+{"GANCICLOVIR": 559.0386598035703, "null": 1.073920800929468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8219.json
index 5bc44a1243b..8b5194a1f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8219.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8219.json
@@ -1 +1 @@
-{"TESTOSTERONE": 3987.402969464821}
\ No newline at end of file
+{"LEMTRADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/822.json
index ec31e134f07..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/822.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/822.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 95.23203747798289}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8220.json
index 6117076b6f0..dc997e9114f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8220.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8220.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9654817102331548}
\ No newline at end of file
+{"BEVACIZUMAB": 10.340992551390933, "IBRANCE": 3.518087435560629, "KEYTRUDA": 1.956542405895426, "KISQALI": 14.151957148948668, "LEMTRADA": 21.74439468860889, "LENALIDOMIDE": 81.81827629756864, "NEULASTA": 205.1008400856755, "PEGASYS": 5.209846730989928, "TRODELVY": 24.273228276241984, "null": 0.4770678789945607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8221.json
index cff747c8798..53eb58e157c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8221.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8221.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2010422006907897, "SILDENAFIL": 23.6167519778792, "VAXZEVRIA": 1.0665641598021376, "VIAGRA": 24.61715033783391}
\ No newline at end of file
+{"ABEMACICLIB": 5.8981201708660285, "ABILIFY": 0.2456228558283877, "ABRAXANE": 3.848992886754123, "ADCETRIS": 29.41691229191931, "AFINITOR": 0.8168263801499, "ALEMTUZUMAB": 0.6502995298378439, "ALIMTA": 6.9106502276361645, "APREPITANT": 0.7734868536590574, "ARAVA": 0.0544390085460606, "ARIPIPRAZOLE": 2.1059773974994225, "ASPARAGINASE": 1.6317447416903772, "ATEZOLIZUMAB": 7.126638846722933, "AUBAGIO": 0.5919599146055623, "AVASTIN": 15.192716077443364, "AXICABTAGENE": 3.941681416305357, "AZACITIDINE": 7.995821449336806, "AZATHIOPRINE": 0.2720106440756673, "BARACLUDE": 0.903842280537658, "BETAFERON": 0.4840754857824311, "BEVACIZUMAB": 11.524601659080467, "BLINCYTO": 9.51351592707919, "BORTEZOMIB": 1.7393544884651322, "BRAFTOVI": 0.3204542859006162, "BRENTUXIMAB": 12.804708737605784, "BRUKINSA": 3.985331950813275, "BUSULFAN": 0.3852110675159445, "CABAZITAXEL": 8.59627498290832, "CABOMETYX": 0.646548336584167, "CAELYX": 0.4413625055519448, "CANCIDAS": 4.241443562328434, "CAPECITABINE": 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2.8420731083858897, "KISQALI": 6.248092525057419, "KYMRIAH": 4.987939989390185, "KYPROLIS": 6.307002339479891, "LEMTRADA": 0.7813381175460322, "LENALIDOMIDE": 6.000005831187788, "LENVIMA": 2.076983816420066, "LEVETIRACETAM": 0.2570540779434924, "LEVOFLOXACIN": 0.5472735071199062, "LONSURF": 4.345476928298887, "LYNPARZA": 16.131385590034768, "MABTHERA": 24.457928119942896, "MAVENCLAD": 2.4952865648934264, "MEKINIST": 1.9207513983459372, "MERCAPTOPURINE": 10.681341817571148, "METFORMIN": 3.0516477482557485, "METHOTREXATE": 2.7147977367558638, "NEULASTA": 6.970128398380074, "NEXAVAR": 0.875364112373022, "NIVESTIM": 10.95394276252234, "NIVOLUMAB": 3.901483877629969, "NUBEQA": 5.86333247139274, "NUCALA": 0.1024570099264824, "OBINUTUZUMAB": 7.683365102059168, "OLANZAPINE": 1.8264714277412588, "OLAPARIB": 1.8000273997519436, "OPDIVO": 3.676145429187547, "PACLITAXEL": 22.89454791394576, "PALBOCICLIB": 10.698972995350609, "PANITUMUMAB": 4.382190066521645, "PAZOPANIB": 0.9269129584616156, 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0.3204692404213329, "TASIGNA": 1.0887627584226989, "TAXOTERE": 13.76337197432074, "TEGAFUR": 46.5933605454822, "TEMODAL": 3.684202822636038, "TEMOZOLOMIDE": 1.0661780849931917, "TEMSIROLIMUS": 6.668299049757854, "TISAGENLECLEUCEL": 22.27787845533811, "TISLELIZUMAB": 47.262203783402434, "TIVICAY": 1.2832144034784114, "TOCILIZUMAB": 2.149915894533707, "TOPOTECAN": 8.934665079638322, "TOZINAMERAN": 0.0366631924616127, "TRASTUZUMAB": 7.749758097102998, "TREMFYA": 0.3267800770374417, "TRODELVY": 3.81623650104666, "VAXZEVRIA": 0.0073792046490153, "VECTIBIX": 10.200712657016911, "VENCLYXTO": 1.8454323062936997, "VENETOCLAX": 5.673746679770883, "VFEND": 0.693804393494435, "VIDAZA": 7.1630388276647485, "VORICONAZOLE": 0.7145027487765132, "VOTRIENT": 0.1479877534829188, "XALKORI": 1.6705736847676425, "XELJANZ": 0.1563584313940907, "XELODA": 15.836277166201668, "XOFIGO": 4.345723984297105, "XTANDI": 0.1374717545344379, "YESCARTA": 1.0295309127792855, "YONDELIS": 3.963931140250513, "ZALTRAP": 13.902036354182746, "ZARZIO": 2.969683931242883, "ZEVALIN": 13.626062095132308, "ZOMETA": 1.5311478194010557, "ZYPREXA": 0.2591962945618182, "null": 1.2829949506990352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8222.json
index d445b7d6dd7..e5a412485d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8222.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8222.json
@@ -1 +1 @@
-{"ADENURIC": 2.181374642818948, "APIXABAN": 1.3842045577568538, "APROVEL": 1.5032301903427945, "ARANESP": 1.0693238290177778, "AVANDAMET": 23.62075395691535, "AVANDIA": 22.866042068495744, "AVASTIN": 1.2098614104345822, "BETMIGA": 1.3148126033761969, "BYDUREON": 2.056739381157648, "BYETTA": 1.0435255146425664, "CHAMPIX": 1.2861120894360176, "CLOPIDOGREL": 3.0829146166854566, "DASATINIB": 3.63460650735159, "ELIQUIS": 7.192627051920292, "ENTRESTO": 1.2661363294416708, "ERLEADA": 1.1480035572946112, "ESBRIET": 1.3561329309104198, "EVENITY": 8.15057614678674, "EVISTA": 11.788808716874918, "EXFORGE": 1.0961033473700603, "EYLEA": 7.290471782483634, "FESOTERODINE": 51.72925328426641, "FILGRASTIM": 1.5131424717984965, "FORSTEO": 1.120421239042839, "GALAFOLD": 5.38140934991934, "HIZENTRA": 2.064851381804484, "HUMALOG": 1.9503220018836416, "ICLUSIG": 3.4443135580174005, "INLYTA": 1.2389813107951386, "JARDIANCE": 1.0426103301018457, "LANTUS": 1.9276889933274584, "LATUDA": 1.3333413171667032, "LIXIANA": 3.9484359472683495, "MEMANTINE": 4.296264435910807, "MEPOLIZUMAB": 2.045139305106808, "MICARDIS": 1.6772953595550582, "MULTAQ": 1.0501523911222488, "NPLATE": 1.7397408646420771, "OFEV": 2.369054124380918, "PEGINTRON": 1.3895243265922432, "PLAVIX": 6.969541862351431, "PRADAXA": 2.454275727849093, "PROTELOS": 3.058145567068717, "RINVOQ": 1.5290538989832498, "ROSIGLITAZONE": 10.861642518248212, "STELARA": 1.33024017741382, "TASIGNA": 4.39126712203474, "THALIDOMIDE": 2.8797802067650737, "TOZINAMERAN": 1.0953915248066444, "VALSARTAN": 1.5054061145837203, "VIAGRA": 2.4243683607311506, "VICTOZA": 1.0721992873333157, "VOTRIENT": 1.9056593226816811, "XARELTO": 1.8901997152883327, "XOLAIR": 1.808250852240558, "XTANDI": 1.510740358905945, "ZOSTAVAX": 1.6506700009722195, "ZYPREXA": 1.0625864571165726}
\ No newline at end of file
+{"AFINITOR": 1.1997506816285417, "ALEMTUZUMAB": 4.187997844849394, "ARAVA": 0.4492700927100482, "ARIPIPRAZOLE": 37.58813250641392, "AZATHIOPRINE": 10.767321037092117, "BEVACIZUMAB": 4.917712268338389, "BUDESONIDE": 0.8695034977929532, "CAELYX": 4.85518163478879, "CANCIDAS": 24.08427274796544, "CARBIDOPA": 11.931293677120903, "CICLOSPORIN": 2.393746871002875, "CLOPIDOGREL": 0.8161780823471833, "COMIRNATY": 0.2168421495127307, "COSENTYX": 1.771917649629395, "CYTARABINE": 2.6854346104900038, "DEXAMETHASONE": 1.029872742903936, "DOCETAXEL": 3.8805571486384896, "DOXORUBICIN": 3.476272047505969, "ELIQUIS": 0.3515983086334625, "ENBREL": 1.9057097747674656, "ENTRESTO": 3.0112822457471373, "EXJADE": 3.251296950215474, "FILGRASTIM": 13.52660983739053, "HUMALOG": 0.5373905861108131, "IBRANCE": 1.3540944091376563, "JAKAVI": 9.571747706181236, "KEYTRUDA": 1.690610550363658, "LEMTRADA": 10.012259346130207, "MEKINIST": 3.19258052973548, "NEULASTA": 17.509674702215186, "OLANZAPINE": 6.995182039302367, "PEGASYS": 0.8242743781712913, "RITUXIMAB": 2.959657810308834, "RUXOLITINIB": 23.806962190466784, "SOLIRIS": 2.2948521153665173, "SPIKEVAX": 0.0392625145600336, "SUTENT": 0.2980289605225039, "TOZINAMERAN": 0.6111656267806751, "VAXZEVRIA": 0.038114856868883, "XELJANZ": 0.8063581705249515, "XOLAIR": 2.5332110599457502, "ZOSTAVAX": 0.7391036333573793, "ZYPREXA": 2.435738739663856, "null": 0.9274244705799068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8223.json
index 11e8c1c1157..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8223.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8223.json
@@ -1 +1 @@
-{"null": 1.840512258020596}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8224.json
index 95c4ab5c99d..3f2348ca646 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8224.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8224.json
@@ -1 +1 @@
-{"ABILIFY": 47.03481217766212, "SUBOXONE": 15.912317491591375, "null": 1.4691439487559408}
\ No newline at end of file
+{"TRUMENBA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8225.json
index d3094d7d6f6..d200a60533d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8225.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8225.json
@@ -1 +1 @@
-{"CICLOSPORIN": 23.565271641428645, "STELARA": 21.44910115924472}
\ No newline at end of file
+{"null": 0.6604911223137445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8226.json
index f6a756c31c8..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8226.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8226.json
@@ -1 +1 @@
-{"null": 4.610415708640639}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8227.json
index eb6b732e9ec..817da7f2f8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8227.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8227.json
@@ -1 +1 @@
-{"ARANESP": 72.57826578094708, "DARZALEX": 19.27926988112287, "EXJADE": 41.05791453028094, "ICLUSIG": 65.54273089259819, "KAFTRIO": 29.988371196912222, "MIMPARA": 44.51280032992484, "NOXAFIL": 31.952443550984203, "OPSUMIT": 33.65818563096437, "SPRYCEL": 8.928009173052821, "TRACLEER": 15.042368387265812, "VENETOCLAX": 41.37399124678456}
\ No newline at end of file
+{"COMIRNATY": 0.1872392637560367, "null": 1.0752057656982512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8228.json
index 928d3af7f19..75f0e3c4156 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8228.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8228.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 23.97433169331449, "ARAVA": 2.799759743348389, "BASILIXIMAB": 62.44376262482477, "CELLCEPT": 106.2384847158186, "CICLOSPORIN": 22.76523346631521, "DACLIZUMAB": 3246.845549148953, "DOXORUBICIN": 18.420336878493973, "GANCICLOVIR": 32.831780158127145, "MYCOPHENOLATE": 21.831008426222034, "SOLIRIS": 9.890275038463871, "SPIRONOLACTONE": 57.08350101015496}
\ No newline at end of file
+{"ALEMTUZUMAB": 27.36082287506253, "CLOPIDOGREL": 4.18089705252009, "COMIRNATY": 0.1465395441473334, "JAKAVI": 11.60156884359678, "LEMTRADA": 60.83023492600508, "SPIKEVAX": 0.2549299707476996, "null": 1.1435106763652487}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8229.json
index 2b054501629..b054164dac3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8229.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8229.json
@@ -1 +1 @@
-{"OPSUMIT": 193.74879499703025, "TRACLEER": 52.327285995031495}
\ No newline at end of file
+{"null": 1.2467472781160776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/823.json
index fb2567433d8..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/823.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/823.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 35.25162962343912, "JARDIANCE": 3.353447651415428}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8230.json
index 59fe35f8973..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8230.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8230.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 111.03563885862272, "BASILIXIMAB": 60.80451264147367, "BUSULFAN": 135.55401003759306, "CELLCEPT": 14.736080887172353, "CICLOSPORIN": 20.50265647936352, "MACI": 2971.3211525250745, "MYCOPHENOLATE": 28.338988784353685, "PEGINTERFERON": 9.662342030301026, "SOLIRIS": 16.061658812125795}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8231.json
index e0952d66f26..362348ad2fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8231.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8231.json
@@ -1 +1 @@
-{"ADVAGRAF": 51.16259280811333, "ALEMTUZUMAB": 51.53554269419166, "AMIKACIN": 11.040073635175988, "ARANESP": 2.1254821356796505, "AZATHIOPRINE": 9.66023080029516, "BASILIXIMAB": 159.5983932521416, "BUSULFAN": 19.32369913481561, "CELLCEPT": 70.06709724646423, "CICLOSPORIN": 28.385830549513955, "DACLIZUMAB": 606.33233441694, "GANCICLOVIR": 52.58484420039505, "MYCOPHENOLATE": 82.47219106475374, "OLYSIO": 10.127033979340144, "PEGINTERFERON": 3.826532961537925, "RAPAMUNE": 63.50580794521762, "SIROLIMUS": 68.93462089310147, "SOLIRIS": 24.032326702736743, "TACROLIMUS": 48.36680142436104, "VFEND": 3.4586118534115737}
\ No newline at end of file
+{"ARIPIPRAZOLE": 3.743890236197738, "AVASTIN": 4.970306288047714, "BUDESONIDE": 5.575686486845673, "CICLOSPORIN": 1.9563575114477505, "COMIRNATY": 0.1420132466657856, "DASATINIB": 47.93547485481319, "DEXAMETHASONE": 4.990014662376734, "FILGRASTIM": 17.766347641778545, "JANUMET": 5.305803263144907, "LEVOFLOXACIN": 2.7887428791459663, "NEULASTA": 7.342697582397224, "NPLATE": 7.265477843620469, "OLANZAPINE": 3.442193474294328, "ROACTEMRA": 4.068244101586006, "RUXOLITINIB": 26.978614278571342, "SUTENT": 1.0520572153140764, "TOZINAMERAN": 0.379857284142713, "VAXZEVRIA": 0.1406374017449267, "XOLAIR": 1.9238938935552417, "ZYPREXA": 1.605225051981526, "null": 1.3719537584447106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8232.json
index d63c385b581..42a3397b8d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8232.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8232.json
@@ -1 +1 @@
-{"CYMBALTA": 3.658687899244266, "IBUPROFEN": 15.19842883217773, "null": 5.140278249338905}
\ No newline at end of file
+{"COMIRNATY": 0.3140210902483517, "null": 0.7200427593387767}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8233.json
index d0afae4ba5f..30f5e9228b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8233.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8233.json
@@ -1 +1 @@
-{"null": 1.4907411152407466}
\ No newline at end of file
+{"COMIRNATY": 2.9535820345516357, "SPIKEVAX": 3.4410963469721625, "VAXZEVRIA": 3.0585825761844507}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8234.json
index 7b9a914e041..4ccba2e9138 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8234.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8234.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
+{"ANAKINRA": 102.9775553547733, "AZATHIOPRINE": 1014.2399334891974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8235.json
index d45b57817f1..bd1db15eb3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8235.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8235.json
@@ -1 +1 @@
-{"ASPARAGINASE": 29.499874221664477, "COMIRNATY": 1.108141990307072, "COVID19": 1.4867933386702907, "VAXZEVRIA": 6.056609635218309}
\ No newline at end of file
+{"null": 24.93064834962373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8236.json
index 1ad0469688b..430823a619f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8236.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8236.json
@@ -1 +1 @@
-{"null": 3.442779540174401}
\ No newline at end of file
+{"CHAMPIX": 2.912122964207541, "CLOPIDOGREL": 1.1205974243392125, "ZOSTAVAX": 2.352522913747228, "null": 26.18494695724264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8237.json
index 3bf1160185f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8237.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8237.json
@@ -1 +1 @@
-{"ATRIPLA": 2.3314990671403426, "ELIQUIS": 9.325613116241495}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8238.json
index 136979eef04..0bb54105149 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8238.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8238.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 3.863633052239384, "ELIQUIS": 16.849723981364953, "PLAVIX": 20.201368983726788, "null": 1.6828639343993654}
\ No newline at end of file
+{"null": 3.33715949250318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8239.json
index 9883baae384..d0a28b7e3b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8239.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8239.json
@@ -1 +1 @@
-{"ELIQUIS": 30.623982985903854, "HEMLIBRA": 261.1155952554108, "KOVALTRY": 891.2060412906651, "PLAVIX": 10.825895147601576, "null": 1.19717855064454}
\ No newline at end of file
+{"ZAVESCA": 73971.8608260369}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/824.json
index c41851f1b49..65f8569ee07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/824.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/824.json
@@ -1 +1 @@
-{"null": 1.6725735676904938}
\ No newline at end of file
+{"ASPARAGINASE": 121.48788414995752, "ONCASPAR": 199.4393686798386, "PEGASPARGASE": 575.9895961791626, "null": 1.4737725646662443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8240.json
index d90a6cc7138..7cb3aa65489 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8240.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8240.json
@@ -1 +1 @@
-{"ELIQUIS": 16.538672437917782}
\ No newline at end of file
+{"AIMOVIG": 12.000850727956998, "COMIRNATY": 0.179259656109946, "JETREA": 897.1759333914919, "null": 1.3313382613782077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8241.json
index cab0a240998..badf89e9b66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8241.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8241.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 3.936149757584813, "ELIQUIS": 33.0706713745353, "ENTRESTO": 8.014231865138628, "PLAVIX": 25.100812869438226, "null": 1.1607173321946895}
\ No newline at end of file
+{"ABACAVIR": 0.1644153514941779, "ABATACEPT": 7.685939104433996, "ADALIMUMAB": 0.861543950324914, "AFINITOR": 0.3165492060235645, "AIMOVIG": 0.5774218616307282, "ALEMTUZUMAB": 0.5354266432195999, "AMIKACIN": 0.8852631405125385, "AMINOSALICYLIC": 1.2938568636600956, "APIDRA": 0.3773058996275784, "APREMILAST": 2.2905177900150364, "ARAVA": 4.958382937414924, "ATRIPLA": 0.1242516489102989, "AUBAGIO": 0.8027845017546789, "AZATHIOPRINE": 5.8854144301066045, "BENLYSTA": 0.3898895081012827, "BRINTELLIX": 5.216931213750459, "BUDESONIDE": 1.0575378979249273, "BUPRENORPHINE": 0.2322827544622271, "BYDUREON": 1.351031814398607, "BYETTA": 0.5284756545691283, "CABOMETYX": 0.5027338332937027, "CAELYX": 0.975389613960592, "CELLCEPT": 0.3158601123404468, "CHAMPIX": 0.7762146555187123, "CHLORHEXIDINE": 0.9405258002463665, "CICLOSPORIN": 0.4069500496196667, "CIMZIA": 1.885356747359156, "CIRCADIN": 3.661918913374096, "CLOPIDOGREL": 0.1716808701374535, "COMIRNATY": 1.1264558058274083, "COSENTYX": 1.992653210740844, "CYMBALTA": 1.0416935854943314, "DEXAMETHASONE": 0.2745873992765343, "DOXORUBICIN": 2.237001474630656, "DULOXETINE": 1.18492443332314, "EFAVIRENZ": 1.1425362814119602, "ELIQUIS": 0.2870507135635307, "ENBREL": 0.4810123615364312, "ENTRESTO": 0.2347239900918285, "ENTYVIO": 1.2078614444510667, "EXJADE": 0.6951002170668487, "FASENRA": 0.4051476608480043, "FASLODEX": 0.7623748417836513, "FORSTEO": 0.8761074844710831, "FORXIGA": 0.3525916542356855, "GARDASIL": 0.7343142197023984, "HERCEPTIN": 0.7555244220661376, "HUMALOG": 0.4387386684198238, "HUMIRA": 0.3358795303947828, "HYDROCORTISONE": 1.7333106388458697, "IBRANCE": 1.1598836984531111, "ICLUSIG": 0.7968923046408103, "IMBRUVICA": 3.336130457799656, "INLYTA": 0.5054254653565005, "ISENTRESS": 1.583295804837247, "JAKAVI": 3.352461665096579, "JANUMET": 0.9874808226134968, "JANUVIA": 0.3577463981151276, "JARDIANCE": 0.5390025824130796, "KAFTRIO": 1.0123664677074466, "KALETRA": 0.8468981830977791, "KEYTRUDA": 0.1193042355998261, "LAMIVUDINE": 1.7648046194674618, "LANTUS": 0.510176316221215, "LEMTRADA": 0.7392708960695042, "LEVEMIR": 0.4291835410524492, "LEVOFLOXACIN": 0.2782792609941539, "LYRICA": 0.6046909263761154, "MEKINIST": 0.7215357002543801, "METHOTREXATE": 0.4102646224659251, "MICARDIS": 1.2720171771271416, "MODERNA": 0.7223541853109898, "NEULASTA": 0.5702277834205468, "NEXAVAR": 0.1240829628394775, "NPLATE": 0.7082360625442506, "NUCALA": 3.4805247397760257, "OCALIVA": 1.8431085643328384, "OCRELIZUMAB": 4.153147057131456, "OPSUMIT": 0.3014029423969752, "PEGASYS": 0.779258261368817, "PEGINTERFERON": 0.6064259355034456, "PEGINTRON": 0.5929413233564624, "PLAVIX": 0.2132044340528243, "RINVOQ": 0.5153917463631879, "RITUXIMAB": 1.0429853206068027, "ROACTEMRA": 0.3580028307391312, "RUXOLITINIB": 2.9029705271776423, "SAXENDA": 0.3613523386107807, "SHINGRIX": 0.9080163862856184, "SIMPONI": 0.735150733739252, "SPIKEVAX": 1.269951500338056, "SPRYCEL": 0.7466132561705605, "STELARA": 1.041133601180109, "STIVARGA": 0.3273261583252664, "SUBOXONE": 0.3376073478945896, "SUTENT": 0.472715019854963, "TAMIFLU": 0.2845637334984082, "TASIGNA": 0.5810759217209643, "TOZINAMERAN": 1.687277125681136, "TWINRIX": 0.6488191411004031, "VAXZEVRIA": 1.904288571452001, "VOTRIENT": 0.2581868777573812, "XELJANZ": 0.9111377528115764, "XOLAIR": 0.3600942217396744, "XTANDI": 0.7279148173093739, "XYREM": 1.4783333371260663, "ZOSTAVAX": 0.439548971708672, "ZYPREXA": 0.1718861119491901, "null": 0.5618551977899499}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8242.json
index 9142d2441cd..0177ad43279 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8242.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8242.json
@@ -1 +1 @@
-{"null": 1.340452940303946}
\ No newline at end of file
+{"ABILIFY": 1.9626582927744187, "ADALIMUMAB": 0.6620515596807606, "AERIUS": 3.300273665338058, "AIMOVIG": 3.228269633468741, "ARAVA": 0.0272527562314529, "ATAZANAVIR": 0.6966997959780563, "ATRIPLA": 0.8901859570713272, "BETMIGA": 2.382205075119483, "BIKTARVY": 8.013305430925737, "BOTULINUM": 43.20361394044385, "BRINTELLIX": 7.466262552079308, "BRIVIACT": 1.3026493177526133, "BUPRENORPHINE": 0.3819446615232194, "BYDUREON": 0.2986627572934903, "CARBIDOPA": 5.141605603502435, "CHAMPIX": 20.71423323981967, "CIRCADIN": 16.279928442093993, "CLOPIDOGREL": 0.1379914221358454, "COMBIVIR": 1.1970180471185492, "COMIRNATY": 0.2061059346603985, "COMTAN": 1.5940215586855584, "COSENTYX": 0.1577397399450199, "CYMBALTA": 16.03963370416974, "DELAMANID": 1.7857572554695815, "DESLORATADINE": 2.6705397704222027, "DEXAMETHASONE": 0.4180972961144689, "DULOXETINE": 0.5942618546719464, "EBIXA": 3.1652504543469275, "EDURANT": 12.394255766578366, "EFAVIRENZ": 1.4831091856970384, "ELIQUIS": 0.4876032385108133, "ENBREL": 0.1615105000417125, "ENTACAPONE": 3.683581612399953, "ENTRESTO": 1.1169499778006864, "ESBRIET": 0.3515996090622656, "ESOMEPRAZOLE": 0.9655081062537328, "EXFORGE": 0.4033791491499481, "FAMPYRA": 0.5491905274178358, "FENTANYL": 0.4681140089660254, "FORSTEO": 0.2946553019136005, "GARDASIL": 0.5024000720609697, "GENVOYA": 4.244136125566038, "GLIBENCLAMIDE": 1.8155216163857748, "HUMALOG": 0.2449557816570957, "IBUPROFEN": 0.4817225038868351, "ISENTRESS": 2.2240212887138915, "JANUVIA": 0.3227757910207381, "JARDIANCE": 0.1506668719626799, "KAFTRIO": 2.735220559854177, "KALETRA": 0.6861358394959663, "KEPPRA": 0.9535926445711342, "LANTUS": 0.1428688279288503, "LATUDA": 2.063048762003044, "LEVETIRACETAM": 0.5444833239238518, "LEVOFLOXACIN": 0.6358529951624361, "LYRICA": 1.1200733942744632, "MELATONIN": 16.000018673218584, "MICARDIS": 0.9562546080507353, "MIDAZOLAM": 0.6749952157086473, "MULTAQ": 0.9221364363481316, "OCRELIZUMAB": 0.5902227345745176, "OLANZAPINE": 0.7611528712805601, "PANTOPRAZOLE": 0.5520767174117215, "PEGASYS": 0.4184409211144399, "PEGINTRON": 0.4232944976409217, "PLAVIX": 0.196556829340374, "RISPERIDONE": 1.490079579695066, "SHINGRIX": 0.2228575323110834, "SIFROL": 3.913379328905386, "SPIKEVAX": 0.2426909556712112, "STALEVO": 2.5097010206155463, "STELARA": 0.1257287899743272, "STRIBILD": 0.2526278513506623, "SUBOXONE": 0.7436634903231936, "SUSTIVA": 8.542291872123538, "SUTENT": 0.077716538104256, "TAMIFLU": 8.08041709435329, "TIVICAY": 5.080839812983594, "TOVIAZ": 0.5478081394042117, "TOZINAMERAN": 0.5100537139861421, "TRIUMEQ": 10.760783163387798, "TRUVADA": 0.1526775475647602, "VARENICLINE": 6.521673110084333, "VAXZEVRIA": 0.416272507013799, "VFEND": 1.3841907770307875, "VIAGRA": 0.4562693093426886, "VIMPAT": 0.976540518214239, "VORICONAZOLE": 0.9243537336158466, "WAKIX": 13.11133970060878, "XELJANZ": 0.1486035123934922, "XOLAIR": 0.2396943650486054, "XTANDI": 1.1723025005076368, "XYREM": 2.909004273096369, "ZYPREXA": 1.052969960344711, "null": 2.328710399745469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8243.json
index b957c93032c..34d0c8d011f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8243.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8243.json
@@ -1 +1 @@
-{"SPINRAZA": 2547.739059467472}
\ No newline at end of file
+{"ACTRAPID": 104.10362586681872, "AP": 3068.614566788939, "AZARGA": 1296.5589549937945, "AZOPT": 1314.909636104503, "CLOPIDOGREL": 5.946160451823843, "DEXAMETHASONE": 5.424016459699607, "IBUPROFEN": 7.631664031108398, "SIFROL": 64.05248677783362, "null": 2.1525067859193365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8244.json
index ac417425793..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8244.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8244.json
@@ -1 +1 @@
-{"AVANDIA": 5.651198721492126, "BUSULFAN": 12.417675481283103, "ELIQUIS": 2.642901775686463, "RITUXIMAB": 6.143339557167915, "null": 1.7318641679508204}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8245.json
index 99fec9ccdff..9fa7380cce0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8245.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8245.json
@@ -1 +1 @@
-{"ABACAVIR": 15.659686250359382, "ABATACEPT": 4.0626569741839, "ADALIMUMAB": 5.551489136058239, "AIMOVIG": 2.3678015546102187, "AMIKACIN": 5.479122433260497, "AMINOSALICYLIC": 2.7115410232339574, "ANAKINRA": 12.741733092693355, "APREMILAST": 6.552691013964545, "ARAVA": 12.305580702433332, "ARIPIPRAZOLE": 1.372888460834734, "ATAZANAVIR": 3.5705765987411344, "AZACITIDINE": 1.683648346694346, "AZATHIOPRINE": 10.166078604398397, "BASILIXIMAB": 1.978769907191391, "BEDAQUILINE": 3.448128834514656, "BEVACIZUMAB": 2.132631690154196, "BIKTARVY": 2.8643513062480093, "BLINATUMOMAB": 2.970588885580719, "BORTEZOMIB": 4.093463112350973, "BOSUTINIB": 5.708643194170404, "BOTULINUM": 5.215984440898126, "BRIVARACETAM": 2.2359148514497305, "BUDESONIDE": 1.9791418361193645, "CABAZITAXEL": 2.291063841935272, "CABOTEGRAVIR": 4.669278648627319, "CANNABIDIOL": 1.9710799752520336, "CASPOFUNGIN": 6.390981139810413, "CEFTAROLINE": 35.35237306579503, "CELECOXIB": 1.2981154220186952, "CERTOLIZUMAB": 4.859685694399646, "CICLOSPORIN": 3.721941170611354, "CIMZIA": 5.491201583971994, "CLADRIBINE": 1.4027127039261855, "COSENTYX": 6.406599800566071, "CUBICIN": 4.689950787381013, "CYTARABINE": 1.857522049641248, "DABIGATRAN": 6.931379670745067, "DACLATASVIR": 75.98729350941606, "DAKLINZA": 65.28348799198957, "DAPTOMYCIN": 14.179412780989914, "DARUNAVIR": 4.003533625580308, "DASATINIB": 13.537682342806146, "DELAMANID": 1.1937242957227003, "DESCOVY": 1.6383592082746457, "DIFICLIR": 11.770362438284357, "DULOXETINE": 2.58561125953696, "ECULIZUMAB": 7.548694838418296, "EFAVIRENZ": 4.467586309852562, "EMTRICITABINE": 5.116650058523083, "ENBREL": 15.9850860835891, "ENTYVIO": 4.196876106119271, "EPCLUSA": 56.59400110519505, "ERELZI": 8.157614729260038, "ERENUMAB": 17.35214544419118, "ERTAPENEM": 9.848499797022344, "ETANERCEPT": 5.132143088343799, "EVEROLIMUS": 1.85037459634998, "EXVIERA": 1.7679231967893572, "FIDAXOMICIN": 21.178076018884656, "FILGRASTIM": 2.052303375484998, "FULVESTRANT": 1.236903161807451, "GANCICLOVIR": 1.5756840031156134, "GEFITINIB": 1.4743647147185783, "GENVOYA": 4.39197973060792, "GLIVEC": 1.412668667173785, "HARVONI": 35.904955202169035, "HUMAN": 1.6927751817811434, "HUMIRA": 3.66524652690179, "HYDROCORTISONE": 1.232392849282932, "IBRUTINIB": 2.6763459800547627, "ICLUSIG": 1.3644728940571285, "IMATINIB": 8.046699336737802, "INFLECTRA": 2.252093557539527, "INFLIXIMAB": 6.058111303742765, "IRINOTECAN": 1.3065395804307491, "IVABRADINE": 5.770739571380053, "KYMRIAH": 1.0811804665146534, "LACOSAMIDE": 7.615125630124234, "LAMIVUDINE": 6.494508487398591, "LEDIPASVIR": 17.78295435024443, "LEFLUNOMIDE": 3.3747016105962957, "LEVETIRACETAM": 2.6931910484583472, "LOXAPINE": 13.916666631202588, "MEKINIST": 1.1244499497229912, "MEMANTINE": 2.2051036223215963, "METHOTREXATE": 6.266377635607415, "MYCOPHENOLATE": 1.3548669290771236, "NILOTINIB": 5.478817510500663, "OLYSIO": 8.773391275663554, "ORENCIA": 6.598547505570691, "PAZOPANIB": 1.386390746879162, "PEGASYS": 1.594867300276254, "PEGINTERFERON": 4.141818999594627, "PEMBROLIZUMAB": 1.230966545857066, "PEMETREXED": 2.949165635338668, "POSACONAZOLE": 5.610299930096147, "PROPRANOLOL": 2.139987627952955, "REBETOL": 1.6198017312467288, "REMICADE": 1.2246638696423542, "RIBAVIRIN": 30.163825690657102, "RITUXIMAB": 1.6986537484737887, "RUFINAMIDE": 110.27445421657272, "RUXOLITINIB": 1.0533157221725105, "SIMEPREVIR": 20.24657257766281, "SOFOSBUVIR": 27.035609476735512, "SOVALDI": 15.409961112093988, "TACROLIMUS": 1.3637874353000303, "TEMOZOLOMIDE": 2.35476778226406, "THALIDOMIDE": 1.2334120376453814, "TOCILIZUMAB": 1.2668705931708857, "TOFACITINIB": 11.94247258971962, "TOPOTECAN": 6.504851253767202, "VEDOLIZUMAB": 5.920606357370708, "VEKLURY": 4.242988779666023, "VORICONAZOLE": 6.608721316496911, "ZEPATIER": 10.099577573633452, "ZONISAMIDE": 5.101233045034793}
\ No newline at end of file
+{"COMIRNATY": 0.3785946422602026, "null": 3.0491837333782144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8246.json
index 2af5f9ceb03..928345c2e05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8246.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8246.json
@@ -1 +1 @@
-{"ABACAVIR": 5.69494683181208, "ABILIFY": 7.779769719925113, "ACTOS": 3.1333872148729798, "ACTRAPID": 3.8613732750715655, "ADEMPAS": 2.185169553759043, "ALISKIREN": 11.479566286681106, "AMIKACIN": 1.1831501755293536, "AMINOSALICYLIC": 2.521055693229441, "ANORO": 2.2992206940686217, "APIDRA": 1.851439545961176, "ARIPIPRAZOLE": 8.514982289072623, "ATAZANAVIR": 9.786167964201455, "BARACLUDE": 5.368834014042079, "BEDAQUILINE": 10.921704923575964, "BETMIGA": 1.9859025729544575, "BEVACIZUMAB": 1.4038525419265624, "BIKTARVY": 15.8617401354794, "BRINTELLIX": 2.8999430864864286, "BRIVIACT": 1.8479856544686664, "BUDESONIDE": 1.7382087943379176, "CABOTEGRAVIR": 8.945569614505716, "CARIPRAZINE": 38.12952200795059, "CELSENTRI": 16.09923868125667, "CLOPIDOGREL": 1.0318270416054591, "COMBIVIR": 3.42792753702361, "DACLATASVIR": 4.588858163537847, "DAKLINZA": 3.1361711498141025, "DARUNAVIR": 26.909697345270796, "DASATINIB": 4.429786961954401, "DELAMANID": 6.030996350635517, "DESCOVY": 11.055109358215985, "DOLUTEGRAVIR": 28.696180028118555, "DULOXETINE": 1.5846268309384854, "EFAVIRENZ": 7.938575362057783, "ELIQUIS": 5.873318441099286, "EMPAGLIFLOZIN": 2.065064144646137, "EMTRICITABINE": 11.136391395592392, "ENTACAPONE": 3.288600916973963, "ENTECAVIR": 4.781881495143108, "ENTYVIO": 5.682477776034311, "EPCLUSA": 12.993678037807232, "EPIVIR": 1.3060221307592343, "ERLEADA": 4.188343084493764, "EXJADE": 3.1948857889591986, "FIASP": 1.795716432410801, "FORXIGA": 1.8913604313829413, "GANCICLOVIR": 1.313264696795119, "GENVOYA": 14.371531536341797, "GLIBENCLAMIDE": 3.5067249534129985, "HARVONI": 4.330842342696448, "ICLUSIG": 4.464177811067646, "INCIVO": 2.0318202868733697, "INCRUSE": 1.430453824450424, "INSULIN": 4.472495109248133, "INVEGA": 15.917303404009376, "INVOKANA": 20.74200184961655, "IRBESARTAN": 1.0664747434427997, "ISENTRESS": 3.653637147819361, "JANUMET": 1.275130812628291, "JANUVIA": 1.2279168138827088, "KAFTRIO": 1.9792294929434089, "KALETRA": 1.4119475705691436, "KALYDECO": 6.345985023492354, "KEPPRA": 3.0218563449361526, "LACOSAMIDE": 3.1059086895020696, "LAMIVUDINE": 4.319787513504023, "LANTUS": 1.6127861116500777, "LATUDA": 3.0342293954792225, "LEVEMIR": 3.863995959109338, "LEVETIRACETAM": 2.425354681140929, "LIXIANA": 2.443507723054619, "LURASIDONE": 13.187563734024057, "LYRICA": 1.0795504593567609, "MEPOLIZUMAB": 1.8574991212223209, "METFORMIN": 3.459413085796258, "MIMPARA": 5.726543965145249, "MIXTARD": 5.101551800741766, "MYCOPHENOLATE": 1.4682946837524185, "NORVIR": 1.700089109452413, "NOVORAPID": 2.207815894259765, "NPLATE": 2.0192496068647863, "OCALIVA": 3.8220451455064, "OLANZAPINE": 6.938691579312748, "OLYSIO": 2.5238475424439133, "OPSUMIT": 2.177255509881366, "ORKAMBI": 10.250656578709323, "PREGABALIN": 1.1816287066347275, "RELVAR": 5.24180192742852, "RIBAVIRIN": 3.250176080624052, "RISPERIDONE": 2.541804564868382, "SIMPONI": 1.4351420592580866, "SOLIRIS": 2.0433348947919527, "SOVALDI": 3.1921722220004702, "SPRYCEL": 1.5938245753101443, "STELARA": 2.105287301714133, "STRIBILD": 1.5176108585814472, "SYCREST": 3.565968694159596, "SYMTUZA": 10.059402853288685, "TENOFOVIR": 7.879381013301568, "TICAGRELOR": 2.6151451612268586, "TIVICAY": 6.366920213471998, "TRACLEER": 1.6302831920365504, "TRELEGY": 2.786538690936756, "TREMFYA": 2.5106829448185186, "TRESIBA": 4.498709346364353, "TRIUMEQ": 5.5202989529101085, "VARENICLINE": 18.98929197707808, "VELTASSA": 8.344193946134597, "VEMLIDY": 9.15822564032372, "VIMPAT": 3.520220791017492, "VIREAD": 2.872559235244783, "XARELTO": 2.304010127136201, "XTANDI": 5.955133806365104, "ZYPREXA": 1.715756039606847, "null": 1.395696959348708}
\ No newline at end of file
+{"null": 1.3727476869860695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8247.json
index fe15f03b0e9..ebf8735b431 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8247.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8247.json
@@ -1 +1 @@
-{"ABILIFY": 2.1176274035231084, "ACTOS": 1.590564523074961, "ADVAGRAF": 1.8296965372163156, "AIMOVIG": 1.6087462246004316, "ALL": 1.6011843775404488, "APIDRA": 1.695014243285006, "ARIPIPRAZOLE": 1.8727259889938304, "ARSENIC": 3.801050519230832, "AUBAGIO": 1.0896101504383875, "AVONEX": 1.18286910769384, "AZILECT": 2.6205309650510564, "BAVENCIO": 1.8066766106623555, "BEXSERO": 1.178729582987643, "BEXTRA": 1.1042069907615473, "BRINTELLIX": 2.187746837964087, "BRIVARACETAM": 1.008545758118674, "BRIVIACT": 1.464139087949682, "CARBIDOPA": 2.1074084762489163, "CHAMPIX": 1.5420749584403255, "CIRCADIN": 1.362047527027515, "COMTAN": 2.934138892122291, "COVID19": 2.5485498019064483, "CYMBALTA": 3.55451544536296, "DALIRESP": 3.217502171068173, "DULOXETINE": 1.2014291642256634, "DUORESP": 3.146140616221603, "DUPIXENT": 1.0240505606142043, "EBIXA": 1.4074681224513483, "ENTACAPONE": 2.879850505920309, "EXELON": 1.2345410493518736, "FAMPRIDINE": 2.1573519936605483, "FAMPYRA": 1.7884087866724734, "FASENRA": 1.120573092802821, "FLEBOGAMMA": 5.859834203035443, "FORSTEO": 1.216727619761059, "FYCOMPA": 1.3870902099409097, "GARDASIL": 1.6093052297322363, "HUMALOG": 1.053603004568341, "INVEGA": 3.6036109735638258, "KEPPRA": 1.4420885358785307, "KETOCONAZOLE": 1.2539408092509436, "KIOVIG": 3.2911689158927584, "KYMRIAH": 1.0747438249832983, "LACOSAMIDE": 1.3236774056070957, "LANTUS": 1.90704651971843, "LATUDA": 3.2009078344346245, "LEMTRADA": 1.222079735547607, "LEVETIRACETAM": 1.340553212007232, "LEVODOPA": 2.4738617204574243, "LOXAPINE": 1.524681734988091, "LUPKYNIS": 2.3838933776968827, "LURASIDONE": 1.3426424285455325, "LYRICA": 1.7085692890167308, "MELATONIN": 1.1934871737800343, "MEMANTINE": 1.520493539172602, "MENVEO": 1.279154583766415, "MIDAZOLAM": 1.0447989726152205, "NEUPRO": 2.0256489370443838, "NIMENRIX": 1.506233556876421, "OLANZAPINE": 2.26519675361044, "PALIPERIDONE": 1.6764634148632611, "PERJETA": 1.37832368229429, "PREGABALIN": 1.1156265896659512, "PRIVIGEN": 1.9951982932744696, "PROPRANOLOL": 1.0877576801228903, "RANEXA": 1.9718275500332916, "RANOLAZINE": 1.415019068817339, "RAPISCAN": 1.621829044513195, "REAGILA": 4.376483914792225, "RELVAR": 1.5261900397646893, "RISPERIDONE": 2.283729310114632, "SELINCRO": 5.122760114248426, "SIFROL": 2.465815858571809, "SITAGLIPTIN": 2.0420897356310355, "STALEVO": 4.080310487581091, "SUBOXONE": 1.3793834320548528, "SYCREST": 1.1684211713163872, "TACROLIMUS": 1.1187849483264112, "TAMIFLU": 1.2897712217992674, "TERROSA": 1.097494227395866, "THALIDOMIDE": 1.3967352324660811, "TOUJEO": 1.2195779000880589, "TOZINAMERAN": 1.3378165952970822, "UMECLIDINIUM": 1.0655129951017177, "VALDOXAN": 2.8932874883865334, "VAXZEVRIA": 1.0442617758254007, "VIMPAT": 1.8565643481538732, "VORTIOXETINE": 2.71015018916042, "XYREM": 2.7968803022383324, "YESCARTA": 2.9958551438361463, "ZAVESCA": 3.5466112609132905, "ZONISAMIDE": 1.3636011812121165, "ZYPADHERA": 1.2866358887324618, "ZYPREXA": 1.8277015736750797, "null": 1.6563030291232024}
\ No newline at end of file
+{"null": 0.9716065362989734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8248.json
index 601458b7f31..118e223d74a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8248.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8248.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 56.35963320296602, "SUBOXONE": 75.99515447246044, "null": 2.256157837439806}
\ No newline at end of file
+{"COMIRNATY": 1.6672048577000256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8249.json
index b2e7b6bb632..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8249.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8249.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/825.json
index c4092eaab50..fc10060c978 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/825.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/825.json
@@ -1 +1 @@
-{"ASPARAGINASE": 94.27717341224188}
\ No newline at end of file
+{"null": 0.9090954767196192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8250.json
index 7144de22563..030666f2ec4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8250.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8250.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 102.5309717712155}
\ No newline at end of file
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8251.json
index 82fe9638d95..5b96655d52e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8251.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8251.json
@@ -1 +1 @@
-{"KEYTRUDA": 18.204563809112955}
\ No newline at end of file
+{"COMIRNATY": 1.9400691336488112, "ENTRESTO": 3.6366776258785545, "ENTYVIO": 4.677537568749773, "NEXAVAR": 1.917546596334187, "SPIKEVAX": 0.7725682128315119, "TOZINAMERAN": 1.43650935257277, "VAXZEVRIA": 0.3734126432189157, "null": 1.8205084708040924}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8252.json
index b9cd5cfb81e..14e35683fe6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8252.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8252.json
@@ -1 +1 @@
-{"KEYTRUDA": 18.72279381698133, "LEMTRADA": 105.4814836629793, "null": 2.169514759494804}
\ No newline at end of file
+{"ABILIFY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8253.json
index f970060d23a..61eb827125f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8253.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8253.json
@@ -1 +1 @@
-{"LEMTRADA": 79.89454199002692, "null": 2.68425082437952}
\ No newline at end of file
+{"CLOPIDOGREL": 29.08386221681284, "COMIRNATY": 1.1194127614118792, "null": 0.8678746950943179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8254.json
index 6ac5d3e5c05..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8254.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8254.json
@@ -1 +1 @@
-{"null": 1.000143026188907}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8255.json
index 7da1a4a0c1c..da84f9216cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8255.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8255.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6075886015628518, "SPIKEVAX": 2.712860085117506}
\ No newline at end of file
+{"ALEMTUZUMAB": 96.10601444904373, "CELECOXIB": 137.6881342924125, "null": 0.4374228915961146}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8256.json
index d02f8bd4421..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8256.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8256.json
@@ -1 +1 @@
-{"null": 4.189697507565455}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8257.json
index 8ec153407f8..37a6aa0fb77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8257.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8257.json
@@ -1 +1 @@
-{"null": 1.3092049495297184}
\ No newline at end of file
+{"ABACAVIR": 0.234029995249312, "ABILIFY": 0.3065040832299532, "ACLIDINIUM": 2.033384056312953, "ADALIMUMAB": 0.1785086547296646, "AERIUS": 5.228411197443711, "ANAKINRA": 9.183549620092911, "APIDRA": 0.9769941903589808, "ARAVA": 0.6545260659394664, "ATAZANAVIR": 2.231708522086153, "AUBAGIO": 0.3753562707538003, "AVASTIN": 0.491089004356065, "AZATHIOPRINE": 0.6037800125662087, "BARACLUDE": 3.566535628533104, "BETAFERON": 2.098320871672575, "BEVACIZUMAB": 0.6731764917687078, "BRINTELLIX": 0.6016061738208369, "BUPIVACAINE": 13.154965287089766, "BYETTA": 0.5826187487982706, "CANCIDAS": 1.8590762995279344, "CELLCEPT": 2.436826818683313, "CHAMPIX": 0.4775516690458029, "CICLOSPORIN": 0.218538738770261, "CLOPIDOGREL": 0.2309622648731149, "COMBIVIR": 1.4626953583393238, "COMIRNATY": 0.0783094838530917, "COSENTYX": 0.2383337942377464, "CYMBALTA": 0.1531569657669161, "CYTARABINE": 0.7388615206484268, "DARUNAVIR": 11.871595454158456, "DEXAMETHASONE": 0.8674518478894091, "DOXORUBICIN": 2.1329943953204333, "ELIQUIS": 4.332340260348958, "EMTRICITABINE": 11.87495387159626, "ENBREL": 1.2472758888369118, "ENTYVIO": 1.7479590317594644, "EPCLUSA": 1.6454600385400917, "ESBRIET": 0.6729555517360508, "ESOMEPRAZOLE": 1.775282657586602, "EXJADE": 0.3682058048662076, "EYLEA": 1.1516655462699237, "FASENRA": 0.9163412038111428, "FASLODEX": 1.2293324314464529, "FENTANYL": 0.4308019709640687, "FORSTEO": 0.6584221659079851, "FORXIGA": 1.209220691967535, "GARDASIL": 3.887933854760525, "HARVONI": 0.7742211340041494, "HEMLIBRA": 4.966154478585073, "HERCEPTIN": 2.3075808163853666, "HIZENTRA": 47.426433805965466, "HUMALOG": 0.2117477339810007, "HUMAN": 36.74473837570227, "HYDROCORTISONE": 1.08974958318473, "IBUPROFEN": 0.8349742291542612, "ICLUSIG": 2.43393812076235, "INSULIN": 0.9331852539372968, "IRESSA": 0.9295206820475588, "ISENTRESS": 4.614523728513489, "JANUMET": 0.4458421867918105, "JANUVIA": 0.8527774131276353, "KEPPRA": 0.5453680891421888, "KEYTRUDA": 0.7418254615112093, "LACOSAMIDE": 2.171717353624054, "LANTUS": 1.0430220795796032, "LEVETIRACETAM": 1.026327971987804, "LEVOFLOXACIN": 0.3453539849370685, "LIXIANA": 1.0932830798457642, "LONSURF": 2.6711274281813404, "LYNPARZA": 5.72571484847963, "METHOTREXATE": 0.4633371132041586, "MIRCERA": 16.87373296956922, "MMRVAXPRO": 2.656756481863554, "NEXAVAR": 1.609352047154578, "OCALIVA": 4.274842085440388, "OPDIVO": 0.652929926626483, "OPSUMIT": 0.2665428094155303, "PANTOPRAZOLE": 0.8341227333716718, "PEGASYS": 3.959864859315759, "PEGINTERFERON": 1.2090285355799102, "PEGINTRON": 0.6681826283566541, "PLAVIX": 0.29702254484391, "PRIVIGEN": 43.0628687564604, "REVATIO": 0.8225607495473626, "RITUXIMAB": 0.5814000967917948, "ROACTEMRA": 12.434792501858592, "ROTATEQ": 1.8334402938561083, "SOLIRIS": 1.1479256675238405, "SPIKEVAX": 0.2032491794100751, "STIVARGA": 1.3724146427404764, "SUBOXONE": 2.319018645205738, "SUTENT": 0.2280571886053304, "TAGRISSO": 2.7729909872459397, "TAMIFLU": 11.22079228665147, "TOCILIZUMAB": 5.226024175090145, "TOZINAMERAN": 0.2484021399368216, "TRACLEER": 0.6068916011792157, "VAXZEVRIA": 0.1368625491934236, "VFEND": 0.5662662826204903, "VIAGRA": 0.9842659996105498, "VIMPAT": 2.1066351862654185, "XELJANZ": 0.1691753293390591, "XOFIGO": 9.262809788397272, "XTANDI": 0.5653782246107085, "ZOSTAVAX": 0.4258835458081639, "ZYPREXA": 0.4578459447638875, "null": 1.6846796744883603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8258.json
index 8c73a085b7d..e6f1387e436 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8258.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8258.json
@@ -1 +1 @@
-{"IBRANCE": 8.27499638243069, "SUTENT": 2.1886140055282137, "null": 1.2432445961880842}
\ No newline at end of file
+{"null": 0.7428750911212086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8259.json
index 809adf9b0af..2b6a128210a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8259.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8259.json
@@ -1 +1 @@
-{"CASPOFUNGIN": 237.0318399428488, "CYTARABINE": 48.17872143441225}
\ No newline at end of file
+{"ALEMTUZUMAB": 17.501022365313826, "AZATHIOPRINE": 12.604166323333622, "BASILIXIMAB": 69.17041958208573, "BUSULFAN": 12.407910060299004, "CELLCEPT": 16.55568843366305, "CICLOSPORIN": 51.240765815448064, "LEVOFLOXACIN": 4.134085978600161, "METHOTREXATE": 4.082695052111509, "MYCOPHENOLATE": 70.4218378211067, "TACROLIMUS": 66.56801510090207, "null": 0.6374979277741676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/826.json
index 112744620db..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/826.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/826.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3970816467745653, "COSENTYX": 14.33221595623343, "GARDASIL": 5.636362887135623}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8260.json
index 86c1d0bc882..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8260.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8260.json
@@ -1 +1 @@
-{"null": 2.562270527944284}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8261.json
index a2d310ef9ae..6f91f42156f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8261.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8261.json
@@ -1 +1 @@
-{"MIDAZOLAM": 56.46123559393571, "null": 1.5986441475080662}
\ No newline at end of file
+{"ABASAGLAR": 5.710478804883988, "ATRIPLA": 0.6521930646890145, "AZILECT": 29.023614939660504, "BETMIGA": 28.62102145270435, "BRAFTOVI": 2.6676686233640123, "BRINTELLIX": 1.6223465957767549, "BYETTA": 1.7262903378512169, "CHAMPIX": 3.3100712653689586, "CIRCADIN": 11.33478305423614, "CLOPIDOGREL": 1.536589015282478, "COMIRNATY": 0.1150480772035228, "CYMBALTA": 0.9723117723955564, "ELIQUIS": 0.8795147951710947, "ENTRESTO": 2.5170997443812606, "EXFORGE": 4.784199975429818, "FORSTEO": 2.6123865708179914, "FORXIGA": 12.571355222653995, "GARDASIL": 0.4402484006772906, "HUMALOG": 0.5710197509296848, "IBRANCE": 0.597700832368028, "JANUMET": 1.9015560488612384, "JANUVIA": 1.3152409832347167, "JARDIANCE": 13.609750309066753, "LANTUS": 0.5100589470064574, "MICARDIS": 3.1292894842723293, "OFEV": 1.88618521771482, "OXYBUTYNIN": 15.065990453928755, "PASIREOTIDE": 116.77161584677452, "PEGASYS": 0.4728688918386276, "PEGINTRON": 1.1610849532781786, "PLAVIX": 0.4824422609625394, "SPIKEVAX": 0.1027569612288422, "SUTENT": 0.6093165398883919, "TOVIAZ": 18.684595985090297, "TOZINAMERAN": 0.0814321655511792, "TRUVADA": 0.6852760860665247, "VAXZEVRIA": 0.1430114005666806, "XELJANZ": 0.7781636715992606, "XTANDI": 4.564941828923853, "ZOSTAVAX": 2.367734550634112, "null": 1.9019545154803856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8262.json
index a3211347e7b..517ffc260d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8262.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8262.json
@@ -1 +1 @@
-{"AFINITOR": 1.0169297990371673, "APIXABAN": 1.3404631539747145, "ARIPIPRAZOLE": 3.744870005923802, "AVANDIA": 4.319504011342207, "BEDAQUILINE": 19.80169817548116, "BRILIQUE": 6.019126721289351, "CLOPIDOGREL": 3.489456976490016, "CYTARABINE": 1.5799945737167798, "DAPAGLIFLOZIN": 35.48981291633555, "ELIQUIS": 1.426610798926395, "ENALAPRIL": 58.410053902137946, "ENTRESTO": 11.18877834642918, "EXJADE": 1.3667874044271775, "IBUPROFEN": 3.992271148059829, "IRBESARTAN": 10.79322902873088, "KALETRA": 3.030593318431765, "NAGLAZYME": 6.41854196340814, "OLANZAPINE": 1.1213755629764872, "OPSUMIT": 1.12047117462845, "PANTOPRAZOLE": 4.351704328288826, "SILDENAFIL": 9.719907738195158, "TASIGNA": 8.219420076582026, "TRACLEER": 3.259277291880033, "VALSARTAN": 8.21231645732534, "XOLAIR": 1.2716834970871531, "ZOSTAVAX": 2.148413063730897, "null": 1.7276830736917608}
\ No newline at end of file
+{"ACLIDINIUM": 102.4710127386318, "BRILIQUE": 47.24109093664536, "COMIRNATY": 0.4157887701658296, "NUCALA": 5.380706712690678, "null": 1.748768861946268}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8263.json
index 0f601593120..4d8e91a9388 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8263.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8263.json
@@ -1 +1 @@
-{"null": 1.9147619606564508}
\ No newline at end of file
+{"null": 2.706453303975637}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8264.json
index 80626b5cf87..fb5bd3a2740 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8264.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8264.json
@@ -1 +1 @@
-{"null": 1.2834699380452856}
\ No newline at end of file
+{"null": 8.728952437938613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8265.json
index 7e5f01a2b7d..33eb2c3e99a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8265.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8265.json
@@ -1 +1 @@
-{"BIKTARVY": 25.901010519695184, "COMIRNATY": 3.0359851947470227, "TOZINAMERAN": 1.087208821127622}
\ No newline at end of file
+{"CARMUSTINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8266.json
index 281942cd939..63a755acd72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8266.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8266.json
@@ -1 +1 @@
-{"COMIRNATY": 3.058257117440734}
\ No newline at end of file
+{"RITUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8267.json
index 50e01651f20..22921af1111 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8267.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8267.json
@@ -1 +1 @@
-{"AIMOVIG": 2.8302517731531687, "AUBAGIO": 5.026025127907129, "CHAMPIX": 1.5994515437966506, "COMIRNATY": 3.029832610545223, "COVID19": 1.3111957038190736, "CYMBALTA": 1.1929330587793778, "FAMPYRA": 31.571853172319333, "LYRICA": 1.6365270095934406, "PREGABALIN": 3.833703533315884, "REBIF": 30.73996218134699, "SHINGRIX": 4.371691530872508, "SPIKEVAX": 1.4146194015586089, "TOZINAMERAN": 1.5095799094022118, "VAXZEVRIA": 1.1304515729156894, "ZOSTAVAX": 6.66856368378855}
\ No newline at end of file
+{"COMIRNATY": 0.7384400662348386, "null": 0.4847839082797997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8268.json
index bee092579ec..65e638af9ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8268.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8268.json
@@ -1 +1 @@
-{"COMIRNATY": 4.41111651378941}
\ No newline at end of file
+{"FENTANYL": 3.9527434697648873, "IRBESARTAN": 13.49443218263164, "LACOSAMIDE": 16.04346081937672, "null": 7.911240285969398}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8269.json
index 90db5b2e478..22f3b64d150 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8269.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8269.json
@@ -1 +1 @@
-{"COMIRNATY": 2.4529419997878774}
\ No newline at end of file
+{"CIALIS": 683.7731034442445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/827.json
index 93021447e21..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/827.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/827.json
@@ -1 +1 @@
-{"ENTYVIO": 220.71514649729505, "GARDASIL": 18.941074702803203}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8270.json
index 0cdbd634218..e7c46eeeb97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8270.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8270.json
@@ -1 +1 @@
-{"COMIRNATY": 1.8179113683427424}
\ No newline at end of file
+{"COMIRNATY": 0.840225600750129, "null": 0.499960377561748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8271.json
index 05298a18ebf..3f53e4d7c59 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8271.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8271.json
@@ -1 +1 @@
-{"null": 1.84449607237132}
\ No newline at end of file
+{"LAMIVUDINE": 98.9965773969692, "MERCAPTOPURINE": 137.04123107892494, "null": 0.8171888511133573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8272.json
index e0345dca283..98308b13b28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8272.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8272.json
@@ -1 +1 @@
-{"ENBREL": 3.824096978500774, "FASLODEX": 6.558724169858598, "HUMALOG": 15.33770460523214, "IBRANCE": 2.800801972186056, "LANTUS": 2.550620985438864, "SIMPONI": 3.368776672478468, "TOZINAMERAN": 1.6718644983756252, "XELJANZ": 8.09978296135574, "ZOSTAVAX": 10.66807378701282}
\ No newline at end of file
+{"ABACAVIR": 0.6877034271059801, "ADALIMUMAB": 1.7629603997364742, "AFINITOR": 1.2169590065627136, "AMIKACIN": 4.606356276354017, "ANAKINRA": 21.068120514371483, "ANORO": 85.73532531818536, "APIXABAN": 13.734927816486818, "ARAVA": 0.8322751453052709, "AZATHIOPRINE": 7.138563016099579, "BENLYSTA": 1.8438689800824477, "BYDUREON": 2.8810307201425376, "CELLCEPT": 1.066367396321149, "CICLOSPORIN": 3.179542390957981, "CIMZIA": 1.3010063028248506, "COMIRNATY": 0.5613845816577102, "COSENTYX": 2.6690554734777767, "CYTARABINE": 2.241301870784812, "DEXAMETHASONE": 0.7735085725668535, "ENBREL": 5.856621075972264, "FASLODEX": 2.319805556738525, "FULVESTRANT": 2.27846538440165, "GARDASIL": 0.700982902691782, "HIZENTRA": 1.403017760024345, "HUMALOG": 0.524437231188072, "HUMIRA": 3.220964140887086, "IBRANCE": 1.22478682961285, "JAKAVI": 1.3420181467659114, "JANUMET": 1.7703433827565709, "KEYTRUDA": 0.6274871072901629, "LANTUS": 0.8387548373621783, "LEFLUNOMIDE": 4.690373760535444, "LEVOFLOXACIN": 0.5151473051830343, "MEKINIST": 1.995339679335141, "MEPOLIZUMAB": 1.0547544773571662, "METHOTREXATE": 7.885799736326497, "NEXAVAR": 0.4740500279550904, "NUCALA": 1.8991549517146369, "OPTIMARK": 2.628598509815405, "PEGASYS": 0.5769601342990721, "PEMBROLIZUMAB": 1.7868796212073708, "PLAVIX": 0.3410922450756616, "RINVOQ": 1.5835261603130406, "RITUXIMAB": 3.529504776717144, "SIMPONI": 1.190685559176986, "SPIKEVAX": 0.4614826092426588, "STELARA": 0.6405553310877613, "SUTENT": 2.0425792440298944, "TOZINAMERAN": 3.3893342327712697, "TRULICITY": 1.213250622941854, "VAXZEVRIA": 0.4224821445654976, "VOTRIENT": 1.25423050951957, "XELJANZ": 4.306715896653896, "XOLAIR": 0.8224319092440694, "null": 0.4993187267969334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8273.json
index f9d58eed2cb..1737d5c7b68 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8273.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8273.json
@@ -1 +1 @@
-{"TRODELVY": 210.4750744130611}
\ No newline at end of file
+{"null": 1.4672362888092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8274.json
index cbfdbac4d74..2cd5bca28bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8274.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8274.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 4.483651446744608, "BRINTELLIX": 2.0073746606918803, "COSENTYX": 3.1392118605221366, "CYMBALTA": 1.7894294513954752, "FENTANYL": 1.4090312347550673, "GARDASIL": 1.4240593856453587, "HUMIRA": 2.3332881177629363, "KEPPRA": 1.082716600787289, "LATUDA": 10.586490390139504, "MMRVAXPRO": 1.4021147119462785, "OLANZAPINE": 1.011441640443791, "SUBOXONE": 1.8134794636149565, "ZYPREXA": 2.063182590581448, "null": 2.6259034489140234}
\ No newline at end of file
+{"ADALIMUMAB": 0.3119204599108283, "ARAVA": 5.497159063291184, "CARMUSTINE": 56.93476936728541, "CELLCEPT": 5.213001349859064, "CICLOSPORIN": 6.203458372498012, "COMBIVIR": 5.592901672522456, "COMIRNATY": 0.069527809803927, "COSENTYX": 1.1833049386282113, "CYTARABINE": 7.635581201386291, "DEXAMETHASONE": 2.763196504593585, "DOXORUBICIN": 6.806077024869822, "ENBREL": 1.3554999737214255, "HUMALOG": 0.9573704687979616, "JARDIANCE": 0.8915150740149361, "KALETRA": 3.196419453294477, "KYMRIAH": 8.82161451713208, "LANTUS": 0.5752016840137727, "NPLATE": 15.2589506438617, "PEGASYS": 0.9822372265175991, "PEGINTRON": 1.2938453042430782, "RITUXIMAB": 5.875826724523357, "SIMPONI": 1.6143361780744645, "SPIKEVAX": 0.0909602938521668, "STELARA": 2.5054768002267047, "TOZINAMERAN": 0.1729895992868888, "ZOSTAVAX": 1.0616110779400525, "null": 1.3531823540693602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8275.json
index c8f5d9445e1..571a225f5cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8275.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8275.json
@@ -1 +1 @@
-{"null": 1.2060823558289395}
\ No newline at end of file
+{"CARMUSTINE": 567.372300187744, "CYTARABINE": 21.526101970521967, "RITUXIMAB": 60.26248834922296, "null": 0.2621395490208459}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8276.json
index 4baddc8cca7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8276.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8276.json
@@ -1 +1 @@
-{"EFAVIRENZ": 152.24539902521903, "FLUTICASONE": 348.6335225485826}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8277.json
index 15a9ed3c4a6..7cc425e585b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8277.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8277.json
@@ -1 +1 @@
-{"COMBIVIR": 67.38625597794434, "KALETRA": 15.563961701253438, "LAMIVUDINE": 52.8840389702044, "PEGASYS": 2.6579682507136004, "SUBOXONE": 6.759020323081387, "null": 1.4745849084719165}
\ No newline at end of file
+{"null": 0.5519605119142673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8278.json
index 500be61e15e..caa93cbafee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8278.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8278.json
@@ -1 +1 @@
-{"COMIRNATY": 2.163403891896227, "SPIKEVAX": 9.75811868638285}
\ No newline at end of file
+{"ADCETRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8279.json
index a40b7d5ef0c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8279.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8279.json
@@ -1 +1 @@
-{"SPIKEVAX": 5.679679993878258}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/828.json
index 20dc4f10670..d6539804d7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/828.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/828.json
@@ -1 +1 @@
-{"JARDIANCE": 20.053690738585853}
\ No newline at end of file
+{"KALETRA": 303.62655420483634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8280.json
index 10503afc9b9..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8280.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8280.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 4.151962780834352, "COMIRNATY": 1.4490970666299738, "DOCETAXEL": 9.02382135245436, "KEYTRUDA": 2.9124180961415327, "LANTUS": 1.833456358919547, "null": 1.1320174091564297}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8281.json
index 975fdd5b825..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8281.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8281.json
@@ -1 +1 @@
-{"APIXABAN": 4.984985173486977, "ARIPIPRAZOLE": 33.05399402030148, "COMIRNATY": 1.9499420377083967, "KEYTRUDA": 3.580713761794635, "OLANZAPINE": 3.7262373177769006}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8282.json
index 66f2a590103..6cc0aea1106 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8282.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8282.json
@@ -1 +1 @@
-{"COMIRNATY": 5.508295369867352}
\ No newline at end of file
+{"SIMPONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8283.json
index 975b8bebff0..ba2bcf08868 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8283.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8283.json
@@ -1 +1 @@
-{"ADCIRCA": 6.494352890782109, "ADENURIC": 11.78349675767964, "ARIPIPRAZOLE": 7.415469978575703, "BRILIQUE": 3.0822479090081094, "CLOPIDOGREL": 4.120204313169427, "COMIRNATY": 2.080719252215529, "DARZALEX": 2.244771514262742, "EMPAGLIFLOZIN": 18.5630518246315, "ENTRESTO": 1.121947970539115, "FENTANYL": 1.8425634886564688, "IRBESARTAN": 5.932421160486333, "JARDIANCE": 4.947883235655883, "KEYTRUDA": 4.445853439112568, "OLANZAPINE": 4.913117012979564, "OPDIVO": 2.364477633319907, "PALIPERIDONE": 33.06369737596907, "PANTOPRAZOLE": 4.382389157100061, "PEMBROLIZUMAB": 2.3393398088714794, "PLAVIX": 1.3928158583167691, "PRIVIGEN": 2.336208483320606, "RIVAROXABAN": 10.404494787869009, "SPIKEVAX": 1.1056786458856478, "TOZINAMERAN": 1.6426699961243858, "TRACLEER": 1.2337355744261775}
\ No newline at end of file
+{"ADALIMUMAB": 4.279958996178615, "CIMZIA": 8.972028118650744, "DAPAGLIFLOZIN": 490.2106149003097, "null": 0.4594744096491015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8284.json
index 2fa90e9b74c..0744198aa48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8284.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8284.json
@@ -1 +1 @@
-{"SPIKEVAX": 40.46109610907418}
\ No newline at end of file
+{"AMPRENAVIR": 683.7381828613328, "ARIPIPRAZOLE": 15.59762698784544, "ASPARAGINASE": 14.418405644262846, "BYETTA": 9.072284187549329, "null": 0.9665397006668792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8285.json
index 6f0482670e5..dfc30a4cc43 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8285.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8285.json
@@ -1 +1 @@
-{"null": 2.4172669215511355}
\ No newline at end of file
+{"ACTOS": 35.87334095451814, "COMIRNATY": 0.8551989667524994, "CYTARABINE": 10.769057248873136, "HUMALOG": 1.4720797551650158, "PEGASYS": 1.0502569077183062, "PEGINTRON": 2.7152423874740137, "PLAVIX": 2.1678820556606646, "SPIKEVAX": 0.5806813726343482, "TOZINAMERAN": 0.6295757999877268, "VAXZEVRIA": 0.6802596846708158, "null": 0.977507066967334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8286.json
index 76be89813aa..f119da362a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8286.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8286.json
@@ -1 +1 @@
-{"ALISKIREN": 426.6712228481429, "null": 2.4448318395062865}
\ No newline at end of file
+{"FENTANYL": 24.40361106209972, "null": 2.5782231515962386}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8287.json
index 7406afa5d33..11f31ea0ebb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8287.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8287.json
@@ -1 +1 @@
-{"null": 7.510767283920724}
\ No newline at end of file
+{"null": 0.8204645188478649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8288.json
index 793a447ab4d..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8288.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8288.json
@@ -1 +1 @@
-{"null": 7.461888341814831}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8289.json
index e5986439eb2..9263fa5f5ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8289.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8289.json
@@ -1 +1 @@
-{"FENTANYL": 12.732089706124317, "null": 6.075504310740033}
\ No newline at end of file
+{"SYNAGIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/829.json
index e331fcc8e19..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/829.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/829.json
@@ -1 +1 @@
-{"ARANESP": 2322.944841193785}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8290.json
index 29338297457..2c888de5cd2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8290.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8290.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.0851499222056482, "ARAVA": 15.27054461304094, "CIMZIA": 16.84121031811707, "COSENTYX": 4.117996980403709, "PEGASYS": 2.172627861645715, "SIMPONI": 8.516111873440064, "STELARA": 59.56436814816962, "XELJANZ": 4.125715514569197}
\ No newline at end of file
+{"ARIPIPRAZOLE": 329.14308956745907, "null": 0.3609475605104554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8291.json
index b0fe8778947..86c115dc440 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8291.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8291.json
@@ -1 +1 @@
-{"LAMIVUDINE": 495.5222310372432}
\ No newline at end of file
+{"null": 3.1854702231412038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8292.json
index 38c9a68a0c8..32929de98ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8292.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8292.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 42.360349954131486, "DEXAMETHASONE": 25.811735876102677, "null": 2.445925557607906}
\ No newline at end of file
+{"BEOVU": 106.17963605536713, "EYLEA": 5223.587249057282, "null": 0.1370202497436943}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8293.json
index e188aff7596..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8293.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8293.json
@@ -1 +1 @@
-{"AFINITOR": 1.5885909568945742, "ALEMTUZUMAB": 1.7826308146771053, "AMIKACIN": 10.360097953491495, "AMINOSALICYLIC": 30.57288789121698, "AZATHIOPRINE": 2.5388070411503327, "BEDAQUILINE": 79.38512672191074, "BENLYSTA": 2.179204434339044, "BIKTARVY": 6.468261637296992, "BUDESONIDE": 1.5628340484724563, "CELLCEPT": 3.95196105175824, "CICLOSPORIN": 4.488949391673467, "CIMZIA": 6.662518110693955, "COMBIVIR": 7.817686107574019, "COSENTYX": 4.601726040171987, "DELAMANID": 31.188292699759064, "DELTYBA": 51.57525033759398, "DEXAMETHASONE": 1.549876398978078, "EFAVIRENZ": 19.47476171192955, "EMTRICITABINE": 10.76878032218702, "ENBREL": 2.732461872641268, "ENTYVIO": 2.8278501675994945, "EPIVIR": 14.217524984773917, "GENVOYA": 7.518712043146201, "HUMIRA": 5.43598098610374, "INCIVO": 1.5690592295453385, "INFLIXIMAB": 9.124205567711488, "JAKAVI": 20.16586588925764, "KALETRA": 4.129926300606878, "LAMIVUDINE": 18.855335508012224, "LEFLUNOMIDE": 6.595812314156319, "LEMTRADA": 2.0179068586295537, "LEVOFLOXACIN": 3.663185332935721, "METFORMIN": 20.661724594586023, "METHOTREXATE": 4.934652508115583, "MYCOPHENOLATE": 4.083420163765368, "NOT": 4.251922774232854, "PEGASYS": 2.311289699114206, "PEGINTERFERON": 3.5212570658391678, "PEGINTRON": 2.0771039166099965, "REMICADE": 8.73934780247895, "RINVOQ": 4.998170287611517, "ROACTEMRA": 5.4307525926416895, "RUXOLITINIB": 10.009631931355113, "SIMPONI": 12.666576930664176, "SKYRIZI": 6.927601925234758, "SOLIRIS": 1.2393196619275686, "SPRYCEL": 1.3938616788864513, "STELARA": 10.695655877914728, "TACROLIMUS": 7.325966222814844, "TIVICAY": 12.91509444304382, "TREMFYA": 10.618850494967962, "VFEND": 1.446186789844233, "XELJANZ": 6.060448717697112}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8294.json
index d9fcec16c57..52bae55147b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8294.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8294.json
@@ -1 +1 @@
-{"FUZEON": 7613.25089238314}
\ No newline at end of file
+{"ARANESP": 396.2585641415277}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8295.json
index bbda8d3ec09..d1c8e17a065 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8295.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8295.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 43.1944194736409, "EFAVIRENZ": 148.4682050411295}
\ No newline at end of file
+{"COMIRNATY": 1.1387581343296962, "null": 0.7673534021882098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8296.json
index 50a71a21a0d..fbc5e833261 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8296.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8296.json
@@ -1 +1 @@
-{"PEGASYS": 4.891064107128184, "PEGINTRON": 10.374034978172435, "SIMPONI": 36.96545125535838}
\ No newline at end of file
+{"ALIMTA": 7.367040542798005, "BEVACIZUMAB": 6.2412450741234125, "CLOPIDOGREL": 1.1112304885523192, "CRIZOTINIB": 148.72150343068327, "DABRAFENIB": 13.876856684339211, "DOCETAXEL": 17.513567983371544, "ELIQUIS": 0.4785744867364556, "GEFITINIB": 28.23458809957795, "IPILIMUMAB": 14.374157110331277, "IRESSA": 4.371656697444121, "LUMYKRAS": 262.62199792081105, "MEKINIST": 60.309910668213085, "OPDIVO": 430.24269236953, "PACLITAXEL": 10.997894707503384, "PEMBROLIZUMAB": 4.548645602882062, "PEMETREXED": 29.84811142501192, "SOTORASIB": 917.6710243441228, "TAGRISSO": 11.60562978054623, "XALKORI": 94.28499747426464, "null": 0.1888977970335765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8297.json
index ca086e31ec7..a071ae86795 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8297.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8297.json
@@ -1 +1 @@
-{"null": 1.1605127259847858}
\ No newline at end of file
+{"ALPELISIB": 332.6209519828068, "PEMBROLIZUMAB": 35.323071885692684, "SOTORASIB": 2736.759079656651, "XALKORI": 149.7730456624511, "null": 0.157805332520006}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8298.json
index 362d1439ad8..6701c05e2a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8298.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8298.json
@@ -1 +1 @@
-{"ADENURIC": 7.123455241857869, "AERIUS": 2.1961648679194203, "ALEMTUZUMAB": 1.352190935791163, "ALIMTA": 8.117682543728291, "APROVEL": 4.172706243859439, "ATAZANAVIR": 5.016448674455195, "AXITINIB": 6.647886705238142, "AZATHIOPRINE": 2.1236268743872397, "BASILIXIMAB": 18.187241978353956, "BIKTARVY": 1.3041626828172228, "BLINATUMOMAB": 8.279905589264084, "BRAFTOVI": 1.57507742489057, "BUSULFAN": 3.4627656282054597, "CELECOXIB": 4.84254576135494, "CELLCEPT": 1.7013586094317423, "CICLOSPORIN": 2.126574854698262, "CRIXIVAN": 9.112639918945137, "CUBICIN": 9.117199007140034, "EFAVIRENZ": 4.816934084225573, "ENTYVIO": 5.084157943884844, "ESOMEPRAZOLE": 10.229963824484969, "FEBUXOSTAT": 8.222750106862218, "FORXIGA": 1.3218983275527818, "GANCICLOVIR": 3.3693175426411206, "HEPSERA": 6.974678317951045, "IBUPROFEN": 4.049356413148567, "INLYTA": 2.1842972752489462, "IPILIMUMAB": 11.279064762142358, "IRBESARTAN": 2.857486746749439, "ISENTRESS": 1.9336380363254435, "KALETRA": 1.5430659418415495, "KEYTRUDA": 10.747953288241854, "KIVEXA": 13.321725348363682, "LEVETIRACETAM": 4.359245735523142, "LEVOFLOXACIN": 5.31491647360492, "MEKINIST": 2.205861343676207, "MICARDIS": 1.4575957998805225, "MYCOPHENOLATE": 2.039295664317062, "NIVOLUMAB": 12.28610223157174, "NORVIR": 4.546324602029553, "OPDIVO": 9.04539935680851, "PANTOPRAZOLE": 8.869809462172421, "PEMBROLIZUMAB": 15.032409516279172, "PEMETREXED": 7.006932152896293, "TENOFOVIR": 5.814511798411333, "TRUVADA": 1.4282942306787691, "VEDOLIZUMAB": 12.044150533428796, "VICTOZA": 1.0815724796399036, "VIREAD": 6.433778344184137, "ZONISAMIDE": 16.623826372446818, "null": 2.317117871052144}
\ No newline at end of file
+{"CLOPIDOGREL": 29.14766247431967, "IRESSA": 145.3852755723312, "KEYTRUDA": 16.986529660325093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8299.json
index 7b9cee2caef..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8299.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8299.json
@@ -1 +1 @@
-{"null": 1.3279972534965905}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/83.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/83.json
index f6c9b1e145b..4cd0e1375a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/83.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/83.json
@@ -1 +1 @@
-{"JARDIANCE": 46.39168022478136, "NOVORAPID": 31.514305333600795}
\ No newline at end of file
+{"ASPARAGINASE": 181.2853996352168, "null": 0.3980944524896245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/830.json
index f9528212330..6c4148a84ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/830.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/830.json
@@ -1 +1 @@
-{"ADENURIC": 1.059011064020959, "AERIUS": 1.494533053450605, "AMBROXOL": 40.79774938731653, "AMLODIPINE": 34.13441854842257, "ATEZOLIZUMAB": 2.3809068100988, "AUBAGIO": 8.004615797996953, "AZILECT": 5.513015280333005, "BETAFERON": 1.2111853011967086, "BETMIGA": 1.1887029707292809, "BRINTELLIX": 1.4580562172813385, "BRIVARACETAM": 1.8902370269248263, "BRIVIACT": 3.756276233966533, "BUPIVACAINE": 1.623177379668406, "CAFFEINE": 24.5753568888814, "CANNABIDIOL": 2.4363098382793997, "CARBIDOPA": 2.569513219974195, "CELSENTRI": 2.378210072975129, "COMTAN": 2.838920545377138, "CONTRAST": 4.5160249647354895, "CYMBALTA": 1.4987512241778933, "EBIXA": 6.028040318918639, "ENTACAPONE": 4.513355337336894, "FAMPRIDINE": 17.061613810611448, "FAMPYRA": 11.360944307690714, "FIRDAPSE": 3.278938069832794, "FORSTEO": 1.6764653332645156, "FYCOMPA": 6.42614955601004, "GARDASIL": 1.2992220819544151, "GILENYA": 3.359439326763692, "IMATINIB": 1.0952798410574858, "INLYTA": 1.1753332402249392, "KEPPRA": 3.131108974804805, "LACOSAMIDE": 2.273378271303595, "LEMTRADA": 1.154383610590919, "LEVETIRACETAM": 1.6593376260130737, "LEVODOPA": 2.636679247003219, "LEVOFLOXACIN": 13.24243098999399, "LYRICA": 2.380580131187978, "MELATONIN": 2.7099050798361635, "MEMANTINE": 1.864221633193119, "MICARDIS": 1.4513669900286732, "MICARDISPLUS": 2.647555381000082, "NEUPRO": 5.218219641160419, "NINLARO": 1.2936443225680112, "OCRELIZUMAB": 6.40007148496775, "OMALIZUMAB": 1.171503909644294, "OXYBUTYNIN": 1.3163608697512037, "PAXLOVID": 3.776642041061872, "PERAMPANEL": 7.2792627732616015, "PLEGRIDY": 2.19049891646544, "PREGABALIN": 1.9748782551696085, "RANEXA": 2.683423784712419, "REBIF": 2.878996748622836, "SHINGRIX": 1.1221302016356578, "TECFIDERA": 5.827939587163809, "TEDUGLUTIDE": 5.616529568335016, "TERIFLUNOMIDE": 4.788713031039936, "THALIDOMIDE": 1.1303034982035485, "TOVIAZ": 1.5359527447453616, "TOZINAMERAN": 1.6369865091265052, "TWINRIX": 1.0852434180775097, "TYSABRI": 4.729869674120376, "VAXZEVRIA": 1.026704118306314, "VIMPAT": 5.726606707078292, "XTANDI": 2.409506461859013, "ZOSTAVAX": 1.8041551025125864, "ZYPADHERA": 5.496747060021855, "null": 1.2407455471980249}
\ No newline at end of file
+{"ACTRAPID": 4.604732110523533, "AFINITOR": 0.7084338592180108, "AIMOVIG": 14.202390116400744, "AMIKACIN": 4.178088750542549, "APROVEL": 6.311208650492318, "BASILIXIMAB": 8.82062798509484, "CELLCEPT": 2.6687915885424327, "CICLOSPORIN": 3.386957578645865, "CLOPIDOGREL": 1.081212323464648, "COAPROVEL": 3.2884906146518005, "COMIRNATY": 0.0676672757780041, "CUBICIN": 5.222896514313198, "DACLATASVIR": 10.4227031742893, "DEXAMETHASONE": 1.0800581932017206, "ELIQUIS": 0.2375322389458107, "ENTRESTO": 4.921701033935137, "ERENUMAB": 86.87076200210286, "EUCREAS": 7.084855627102629, "EXFORGE": 2.5336996573190254, "EXJADE": 2.342633833001168, "FENTANYL": 2.54843334382937, "FORXIGA": 1.8406652756862047, "GALVUS": 3.4127886797724782, "GLIBENCLAMIDE": 12.081899525524816, "IBUPROFEN": 7.2769335264959665, "INCIVO": 1.6083041561395903, "IRBESARTAN": 6.395079655963421, "JANUMET": 2.3120838177425407, "JANUVIA": 1.4892245928199217, "JARDIANCE": 1.0116943392202462, "KALETRA": 1.6656094115673428, "KEPPRA": 0.3160509963390635, "LEVETIRACETAM": 1.71837834764099, "LEVOFLOXACIN": 0.7917300847460509, "METFORMIN": 10.079941522585113, "MICARDIS": 4.070465430069324, "MIDAZOLAM": 2.1279029565978065, "OLANZAPINE": 0.6162757162030983, "OLYSIO": 3.2301788820576784, "OPDIVO": 1.2402306777908916, "OPSUMIT": 0.9354266391438564, "PRIVIGEN": 1.5543983907018974, "RASILEZ": 3.9037176749672513, "SOLIRIS": 5.161571915354844, "SPIKEVAX": 0.0411751201782751, "SUTENT": 0.7710640548024579, "TOZINAMERAN": 0.0573732056026357, "TRACLEER": 2.339000068891427, "TRUVADA": 0.236137217724558, "VAXZEVRIA": 0.065656313476147, "VFEND": 2.5166156093434524, "XELEVIA": 95.8692694470784, "ZONISAMIDE": 18.93129004190845, "ZYPREXA": 0.6307278802114675, "null": 2.6159539036243724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8300.json
index d9cd9056f94..486dc9ade18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8300.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8300.json
@@ -1 +1 @@
-{"KEYTRUDA": 51.060604991998346}
\ No newline at end of file
+{"null": 0.3714687163175711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8301.json
index 06c4046ccea..7623b8de1a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8301.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8301.json
@@ -1 +1 @@
-{"NEXAVAR": 126.33581840400608}
\ No newline at end of file
+{"null": 4.7897036450259245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8302.json
index 99b43f01329..c12d274b236 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8302.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8302.json
@@ -1 +1 @@
-{"KEPPRA": 6.791161402033722, "NUCALA": 12.919994594572508, "VOTRIENT": 45.44968984877484, "null": 1.4502639809654994}
\ No newline at end of file
+{"null": 1.308269228709178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8303.json
index 303283524e2..8cf48d46920 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8303.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8303.json
@@ -1 +1 @@
-{"FASLODEX": 39.26992092736663}
\ No newline at end of file
+{"COMIRNATY": 1.0975924152123442, "GARDASIL": 7.371081007566778, "RITUXIMAB": 21.393384073508525, "SPIKEVAX": 0.4299951951909999, "TOZINAMERAN": 3.3071242673260968, "VAXZEVRIA": 0.9458214162660769, "null": 0.2772948372196766}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8304.json
index 1bace5d0609..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8304.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8304.json
@@ -1 +1 @@
-{"AFINITOR": 2.132898641627506, "AVASTIN": 17.69082901016076, "BRAFTOVI": 7.010344678232548, "CABOMETYX": 8.396707796121122, "CLOPIDOGREL": 6.104643621525225, "ELIQUIS": 8.457901856553727, "IBRANCE": 2.2090879581435483, "INLYTA": 4.658695431419001, "KEYTRUDA": 7.391718511988311, "LENVIMA": 84.89722879375826, "NEXAVAR": 20.554212242039533, "OPDIVO": 7.962916417110066, "PLAVIX": 2.688830446313793, "STIVARGA": 16.490273241596334, "SUTENT": 17.858841824044323, "VOTRIENT": 9.312143106967412}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8305.json
index d0c48b56efc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8305.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8305.json
@@ -1 +1 @@
-{"KEYTRUDA": 100.93320344107418, "PEMBROLIZUMAB": 286.3694136234043}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8306.json
index 5452fe8cec0..9d8e94eb53b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8306.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8306.json
@@ -1 +1 @@
-{"JANUMET": 72.69131295059448, "NEXAVAR": 15.693968202299128}
\ No newline at end of file
+{"ADALIMUMAB": 2.451852486064743, "COMIRNATY": 1.344802973473305, "IBRANCE": 1.8819238566630327, "SPIKEVAX": 0.9081325934419382, "SUTENT": 4.421186071343388, "TOZINAMERAN": 0.283683209944681, "VAXZEVRIA": 0.7994486996739937, "null": 0.8922552160978416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8307.json
index 1bd8443aab3..604c17ad3b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8307.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8307.json
@@ -1 +1 @@
-{"ASPARAGINASE": 10.972282079807687, "AVASTIN": 2.1553987684089586, "AXICABTAGENE": 55.43007643811781, "AZACITIDINE": 72.42978168997577, "BEVACIZUMAB": 3.112194799622257, "BLINCYTO": 42.451017519193314, "BORTEZOMIB": 25.30212047094461, "BRAFTOVI": 5.508474163760502, "CARFILZOMIB": 36.2736609350323, "CYTARABINE": 14.06014717213332, "DARZALEX": 17.801571727913366, "DEXAMETHASONE": 10.714436601276576, "DOCETAXEL": 3.306028825119776, "DOXORUBICIN": 15.637144222325285, "FASTURTEC": 52.99487645992284, "GAZYVARO": 111.77361695970691, "HERCEPTIN": 4.192336474724116, "IBRUTINIB": 31.630603538295382, "IMBRUVICA": 22.484426672495147, "JAKAVI": 2.997671488307312, "JEVTANA": 8.03179958758369, "KEYTRUDA": 3.0199734313850017, "KYMRIAH": 10.239030383835916, "KYPROLIS": 72.67557157412313, "LENVIMA": 22.158735252069334, "MABTHERA": 5.392357082724299, "MEKINIST": 1.5058129473263222, "METHOTREXATE": 2.831198008371969, "NEXAVAR": 4.022796509248779, "OBINUTUZUMAB": 105.11442352676312, "OPDIVO": 4.7530033151256585, "POTELIGEO": 30.5488812903053, "RASBURICASE": 142.40462717353353, "RITUXIMAB": 20.2613060708329, "RIXATHON": 15.228527141675633, "SORAFENIB": 15.731632606322991, "SPRYCEL": 3.2651310485254226, "SUTENT": 3.595884119268597, "TASIGNA": 1.9371613770560507, "THALIDOMIDE": 8.188848339258541, "TISAGENLECLEUCEL": 45.50688407212719, "VELCADE": 22.633976958755504, "VENCLYXTO": 151.95913557135515, "VENETOCLAX": 219.76394475950687, "VIDAZA": 90.17712433636484, "VOTRIENT": 1.574139698788799}
\ No newline at end of file
+{"COMIRNATY": 2.6874964890433706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8308.json
index c7cc3f516ad..efee221b6c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8308.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8308.json
@@ -1 +1 @@
-{"FASLODEX": 58.23685796226458, "IBRANCE": 30.67250128328673}
\ No newline at end of file
+{"COMIRNATY": 1.53515910939341, "MMRVAXPRO": 14.41155945541538, "VAXZEVRIA": 0.4309562734512088, "null": 1.0975023240533794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8309.json
index 67bd49e5c2d..778f4aad1f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8309.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8309.json
@@ -1 +1 @@
-{"ABEMACICLIB": 96.50616766760608, "ABRAXANE": 50.55661377691028, "AFINITOR": 20.60607414766788, "AVASTIN": 5.24900191594458, "BEVACIZUMAB": 5.829688411666147, "CAPECITABINE": 20.820287401022053, "DENOSUMAB": 20.024837824377897, "EVEROLIMUS": 19.677953169321498, "FASLODEX": 110.92780135158068, "FULVESTRANT": 54.70990257553316, "IBRANCE": 34.73626356611721, "ICLUSIG": 6.6734482241142175, "IRESSA": 11.504208316702814, "KEYTRUDA": 3.551644976559348, "KISQALI": 25.20782291049756, "LYNPARZA": 48.00345852090853, "NEXAVAR": 5.3202378299742366, "RIBOCICLIB": 18.321001091922437, "RUBRACA": 27.72934008417512, "STIVARGA": 16.638654375736774, "TAGRISSO": 11.272312365499168}
\ No newline at end of file
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/831.json
index 57217e0e1ef..1d9bbee92e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/831.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/831.json
@@ -1 +1 @@
-{"EMPAGLIFLOZIN": 218.7026727542693, "FORXIGA": 74.76539324589217, "JARDIANCE": 271.809110623827}
\ No newline at end of file
+{"ABACAVIR": 0.2129175794555651, "ABASAGLAR": 0.1789293295826229, "ABATACEPT": 1.3563596268306863, "ABILIFY": 2.3211456624946027, "ACLIDINIUM": 1.1788966875889324, "ACTOS": 0.8128631668440167, "ADALIMUMAB": 0.89820467210218, "ADCIRCA": 0.783867815443838, "ADEMPAS": 0.5483367317910373, "AERIUS": 1.132146379486642, "AFINITOR": 0.377251776938429, "AGOMELATINE": 3.07090957720799, "AIMOVIG": 1.5130932500528853, "ALEMTUZUMAB": 0.3745946390752672, "ALENDRONATE": 5.083037549053048, "ALIMTA": 0.1056993117174915, "ALISKIREN": 6.050632562910637, "ALL": 0.7112398791522715, "ALPELISIB": 0.5237031476654816, "AMBRISENTAN": 0.6371666724289247, "AMINOSALICYLIC": 0.2814136214143209, "ANORO": 4.184483921032506, "APIDRA": 0.3221962084726052, "APIXABAN": 2.562712063924804, "APREPITANT": 0.2017311600050516, "APROVEL": 0.4375257439849886, "ARANESP": 0.0635518896414122, "ARAVA": 0.3031514007920943, "ARIPIPRAZOLE": 1.2622990367641147, "ARSENIC": 5.906182057917096, "ASPARAGINASE": 0.2080284550960313, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8310.json
index dcfebc25f2d..ca552237f2f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8310.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8310.json
@@ -1 +1 @@
-{"AFINITOR": 8.066318615528973, "AVASTIN": 21.54500577577872, "BEVACIZUMAB": 59.87721328503066, "CABOMETYX": 19.21074184229666, "EVEROLIMUS": 96.702265388255, "KEYTRUDA": 15.667133427577475, "NEXAVAR": 22.585449187161284, "STIVARGA": 18.155347248931783, "SUTENT": 4.978590369086888, "VOTRIENT": 12.057308322147298}
\ No newline at end of file
+{"ENOXAPARIN": 290.96163174710216, "FENTANYL": 31.549220067542983, "null": 1.0499739029471826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8311.json
index f6e14b675b8..9b91711ff55 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8311.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8311.json
@@ -1 +1 @@
-{"IBRANCE": 9.453540647256586, "KEYTRUDA": 6.876141952934418, "STIVARGA": 14.553877713781176, "SUTENT": 23.993816105382432, "VOTRIENT": 30.132106336247368}
\ No newline at end of file
+{"HUMALOG": 3.319760901951688, "HUMIRA": 12.29965124554682, "KEPPRA": 4.063534135222749, "null": 2.3014607114043506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8312.json
index 9d7ea5dda1f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8312.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8312.json
@@ -1 +1 @@
-{"AVASTIN": 106.34188424390754}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8313.json
index 363cec3dcc6..8e5e98d6901 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8313.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8313.json
@@ -1 +1 @@
-{"IPILIMUMAB": 61.98276320803039, "KEYTRUDA": 81.37858774211624, "OPDIVO": 62.74309221286461, "PEMBROLIZUMAB": 184.13392856790887, "TEMOZOLOMIDE": 488.9504675403912}
\ No newline at end of file
+{"null": 3.5399459944207345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8314.json
index 6c0af50d3f3..85787f5b529 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8314.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8314.json
@@ -1 +1 @@
-{"LENVIMA": 53.60569918896044, "NEXAVAR": 59.175492977968176, "SUTENT": 26.251617964191645}
\ No newline at end of file
+{"null": 3.1764301432564133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8315.json
index 3e7d1dab1e4..0ac4bf6d719 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8315.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8315.json
@@ -1 +1 @@
-{"NEXAVAR": 148.05952665516938}
\ No newline at end of file
+{"null": 1.3804336863951758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8316.json
index f05d2539bd8..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8316.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8316.json
@@ -1 +1 @@
-{"CHAMPIX": 4.359874933571327, "GARDASIL": 1.9950079091622168, "PEGINTRON": 3.1594182052319075, "SPIKEVAX": 1.254208714619021, "TOZINAMERAN": 3.363362977826567, "VIAGRA": 6.230160285141155, "null": 1.179219808153962}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8317.json
index 7b9cee2caef..fde9149f0a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8317.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8317.json
@@ -1 +1 @@
-{"null": 1.3279972534965905}
\ No newline at end of file
+{"ATOSIBAN": 168024.3977411458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8318.json
index aa3d11a7d05..1b1c194dddd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8318.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8318.json
@@ -1 +1 @@
-{"CIMZIA": 17.944659623278998, "KEPPRA": 24.062238392646528, "REYATAZ": 127.26107473158744}
\ No newline at end of file
+{"ABILIFY": 6.232757513569969, "AIMOVIG": 4.302739023056499, "ANTIBIOTICS": 32.74166895002574, "ATAZANAVIR": 14.064398786905986, "AZATHIOPRINE": 32.661457823250295, "CICLOSPORIN": 5.1023512067925125, "CINACALCET": 46.40508512384153, "COMBIVIR": 40.04443202687385, "COMIRNATY": 0.0725816640389284, "COSENTYX": 3.968062730821756, "DEXAMETHASONE": 4.563960430669018, "EFAVIRENZ": 18.83170393825188, "ESOMEPRAZOLE": 8.50591234195522, "FENTANYL": 2.228122350577024, "IBUPROFEN": 2.9850252416662397, "KALETRA": 3.082458860494372, "KEPPRA": 1.1191054769484534, "MIDAZOLAM": 4.362808729032698, "NORVIR": 16.84186026990361, "OLANZAPINE": 2.877750509856146, "OMALIZUMAB": 2.9099255665964208, "OPSUMIT": 1.2752416534510904, "REYATAZ": 47.3521230043124, "SPIKEVAX": 0.1372188461004975, "SUFENTANIL": 9.741556511994713, "TRACLEER": 3.4407828708352364, "XOLAIR": 14.595419058219372, "null": 1.8263996570130436}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8319.json
index bdde0bea380..4e29365a5be 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8319.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8319.json
@@ -1 +1 @@
-{"null": 1.598884383693937}
\ No newline at end of file
+{"COMIRNATY": 0.3114162735149856, "null": 0.8397939546431998}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/832.json
index 880b945db9f..fddbf36ef58 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/832.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/832.json
@@ -1 +1 @@
-{"COMPRESSION": 357.265502649812, "EMPAGLIFLOZIN": 46.544787654675865, "FORXIGA": 187.3669685846062, "JARDIANCE": 500.0130687873869}
\ No newline at end of file
+{"ABILIFY": 9.06751849484344, "AMIKACIN": 9.656380191759064, "ARIPIPRAZOLE": 2.503564679184128, "BIKTARVY": 3.982353311394032, "BUMETANIDE": 42.010011533516206, "CHAMPIX": 4.780703734414313, "COMIRNATY": 0.594853141756343, "CYMBALTA": 3.199711244801668, "ELIQUIS": 0.6082108757327553, "EPADERM": 445.15862442643135, "FENTANYL": 3.0411759723014677, "GARDASIL": 3.542877015599678, "JANUVIA": 2.6078026570130275, "JARDIANCE": 4.386966190693309, "KEPPRA": 1.4779378512615668, "LEVETIRACETAM": 3.872946813867824, "PEGASYS": 0.7214008217018026, "PEGINTRON": 1.256319180031669, "PLAVIX": 0.9852837069291902, "SPIKEVAX": 0.403622541215904, "TOZINAMERAN": 0.1468157977358777, "VAXZEVRIA": 0.1285637737375679, "ZOSTAVAX": 4.291187070023269, "null": 1.4938127642269514}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8320.json
index f792e3e121b..66b69631af1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8320.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8320.json
@@ -1 +1 @@
-{"MMRVAXPRO": 60.92190509399489}
\ No newline at end of file
+{"null": 1.1852302252440632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8321.json
index ca7207d9b7e..536d51d6a63 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8321.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8321.json
@@ -1 +1 @@
-{"PEGASYS": 2.180159899447024, "SIMPONI": 5.2546695047423215, "null": 1.09889622866779}
\ No newline at end of file
+{"null": 3.484806290653003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8322.json
index 7c4fdfbde97..f2604813ef7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8322.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8322.json
@@ -1 +1 @@
-{"null": 2.2142953271576955}
\ No newline at end of file
+{"ENTRESTO": 13.617549779275077, "null": 1.877060246025912}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8323.json
index 672cef74457..105915a3141 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8323.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8323.json
@@ -1 +1 @@
-{"ASPARAGINASE": 2.793739560365604, "ATAZANAVIR": 3.223741427804724, "AXITINIB": 5.437023362398193, "BIKTARVY": 1.676784032469055, "BYETTA": 1.9170530773638932, "CELLCEPT": 1.5391615865151091, "CHAMPIX": 1.0749112065935456, "CRIXIVAN": 4.500700291366508, "FORXIGA": 1.3878021281451924, "GARDASIL": 3.632634075617855, "HUMALOG": 1.3048435823319686, "HUMIRA": 2.6441424246613408, "INFANRIX": 11.772646214845746, "INLYTA": 4.835605421252635, "INSULIN": 3.422614382687812, "INTRONA": 11.643094586855527, "IPILIMUMAB": 39.60417912390341, "JANUMET": 1.0024034064124745, "JANUVIA": 1.6048051490983208, "JARDIANCE": 1.7073730695573477, "KEYTRUDA": 34.41108926411956, "LEMTRADA": 2.680401902852073, "LEVEMIR": 1.723118967656597, "LIBTAYO": 15.369091241456855, "MMRVAXPRO": 1.068878691712018, "NIMENRIX": 2.885338219304841, "NORVIR": 3.2835210247272197, "OLANZAPINE": 2.2965221425861517, "OPDIVO": 21.305147466049306, "PEGASYS": 5.593327030678427, "PEGINTERFERON": 7.587471402362171, "PEGINTRON": 21.897156254167225, "PEMBROLIZUMAB": 29.26185608868576, "RIBAVIRIN": 3.659968100447061, "SOMATROPIN": 7.415810809777687, "ZYPREXA": 14.301828932237015}
\ No newline at end of file
+{"ANORO": 386.3410094888442, "APIXABAN": 59.91913042340991, "ARANESP": 17.118623679794116, "AVANDIA": 1.7998484519923332, "AZATHIOPRINE": 21.421151204657374, "BRIDION": 18.674378491525665, "CICLOSPORIN": 1.243930710389834, "CLOPIDOGREL": 1.3146455452628336, "COMIRNATY": 0.0499567534908209, "ELIQUIS": 0.9105884848329346, "JANUVIA": 3.553495622279256, "KEPPRA": 1.3712546127205345, "NPLATE": 6.497698601778965, "PLAVIX": 2.1959652531808382, "null": 0.6078403947847834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8324.json
index 439e34aae45..f94436dd741 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8324.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8324.json
@@ -1 +1 @@
-{"null": 2.040534036553507}
\ No newline at end of file
+{"ARANESP": 3.054271861689984, "BYETTA": 3.55184204835388, "CICLOSPORIN": 2.0588357876567223, "CLOPIDOGREL": 4.210700933230806, "COMIRNATY": 0.0688654284347881, "JANUVIA": 3.7727303207559895, "LEFLUNOMIDE": 13.653590527731671, "PEGINTRON": 3.962046917388971, "PLAVIX": 4.63829797036092, "SPIKEVAX": 0.1727560872987176, "VAXZEVRIA": 0.0651890055008942, "ZOSTAVAX": 2.497543603204686, "null": 1.1629046251506117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8325.json
index 8dd9db9cd27..b4abb09903d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8325.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8325.json
@@ -1 +1 @@
-{"ABATACEPT": 2.1298724282569634, "ABILIFY": 2.077054226881724, "ACLIDINIUM": 19.028015269109563, "ADALIMUMAB": 4.1042977634987, "AFINITOR": 1.2469593302218775, "AGOMELATINE": 20.76083486774135, "AMINOSALICYLIC": 1.5196612775782252, "APREMILAST": 1.4194942954694634, "APROVEL": 1.6313215056344452, "ARAVA": 4.928721738995066, "ARIPIPRAZOLE": 1.452254771374668, "ASPARAGINASE": 1.3043531937803725, "AVASTIN": 1.2684320422191857, "BIKTARVY": 1.075863074398148, "BUDESONIDE": 13.39667373080051, "BYDUREON": 7.495532290550348, "CANAGLIFLOZIN": 85.63184190946521, "CIMZIA": 2.7173077331078144, "CLOPIDOGREL": 1.819086062945097, "COAPROVEL": 4.672413457709076, "COSENTYX": 2.3279311612414126, "DAPAGLIFLOZIN": 4.25039460288018, "DARUNAVIR": 3.7856860679563913, "EMPAGLIFLOZIN": 2.287267907190837, "ENTRESTO": 1.7769271525905213, "EXFORGE": 3.255823184513652, "FASLODEX": 1.1223555716446716, "FORXIGA": 3.123563045580182, "HUMIRA": 4.883950880247271, "ICLUSIG": 1.1541016928068315, "IMATINIB": 3.774559951740285, "INVOKANA": 10.16238964797084, "IRBESARTAN": 1.9933317786456493, "JANUMET": 2.1289501421652712, "JANUVIA": 2.431855441583918, "KALETRA": 1.1803907702828675, "KEYTRUDA": 1.5192894968159143, "LATUDA": 1.3192159590723085, "LEFLUNOMIDE": 1.8750681108915948, "LYRICA": 2.123096234314381, "METFORMIN": 13.024930574956072, "OLANZAPINE": 3.0062617417180237, "OMALIZUMAB": 2.241540216248345, "ONGLYZA": 6.253683177396747, "PASIREOTIDE": 23.623451677332252, "PIOGLITAZONE": 80.67181806877197, "SOMATROPIN": 6.847951891042719, "SPIRONOLACTONE": 2.373816391411525, "STELARA": 1.467077751532624, "TASIGNA": 2.289257638937851, "TOVIAZ": 1.0667887479487146, "TREMFYA": 1.0460044863730338, "VIAGRA": 3.30274636041995, "ZOSTAVAX": 6.19144527342971, "ZYPREXA": 34.115576957815925}
\ No newline at end of file
+{"ALEMTUZUMAB": 71.5477932790114, "null": 0.2347142377773155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8326.json
index f0133297d5c..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8326.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8326.json
@@ -1 +1 @@
-{"AZATHIOPRINE": 128.57006553652965, "THALIDOMIDE": 200.82207246801983, "null": 2.1971999613674265}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8327.json
index 68ae25f894b..d9befd121f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8327.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8327.json
@@ -1 +1 @@
-{"AIMOVIG": 1.8919203665935336, "APIDRA": 3.5320080350561143, "BRIDION": 29.990195779020286, "CHLORHEXIDINE": 3.2516574980273902, "DEXAMETHASONE": 7.268901896268634, "ENOXAPARIN": 4.01648118204852, "FENTANYL": 2.821553222754226, "INSULIN": 5.945508902729597, "LEVOFLOXACIN": 9.03871718309368, "MIDAZOLAM": 7.4184987359905294, "OMALIZUMAB": 1.4209319362361197, "SUFENTANIL": 50.08235675337304, "XOLAIR": 4.032933074165289, "null": 4.3693709790579325}
\ No newline at end of file
+{"ASPARAGINASE": 731.7837258096637, "CICLOSPORIN": 15.57197771444326, "CYTARABINE": 23.799004635289663}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8328.json
index 18f6ae34ea8..fa589c1cfb4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8328.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8328.json
@@ -1 +1 @@
-{"null": 3.891465979519322}
\ No newline at end of file
+{"KEPPRA": 7.339464321910832, "null": 6.447385570417167}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8329.json
index f48317f12ec..0bcb267c47e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8329.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8329.json
@@ -1 +1 @@
-{"APIDRA": 47.4973388468732, "GARDASIL": 4.682837326379925, "INSULIN": 21.882097754320576, "MENVEO": 42.5449656612914, "XOLAIR": 9.123314363409628}
\ No newline at end of file
+{"COMIRNATY": 0.0629022918197853, "HUMALOG": 2.330745816475938, "null": 1.6490811209641665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/833.json
index 536c81c828b..c996cff842e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/833.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/833.json
@@ -1 +1 @@
-{"null": 2.3710324922897565}
\ No newline at end of file
+{"GARDASIL": 52.9345240341982, "null": 0.7783440919244126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8330.json
index 545511dc792..54ce361be21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8330.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8330.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 53.46692491119072, "ZOSTAVAX": 47.19605635139588}
\ No newline at end of file
+{"null": 4.29790114419221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8331.json
index 5d2a0467cf5..84e757b272f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8331.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8331.json
@@ -1 +1 @@
-{"ACTRAPID": 35.18247295899008, "ANAKINRA": 14.933718151158471, "APIDRA": 2.6959263537112155, "BUDESONIDE": 1.383216645594425, "ENOXAPARIN": 11.183205358346154, "IBUPROFEN": 4.558801500318839, "LIXIANA": 11.464208883399063, "XOLAIR": 1.6990391967538727, "null": 3.279767481563943}
\ No newline at end of file
+{"CICLOSPORIN": 1.3664921875737934, "COMIRNATY": 2.231270682108848, "MODERNA": 4.97499408177851, "NIMENRIX": 8.053803198433927, "PRIVIGEN": 22.83840439617604, "SHINGRIX": 2.1055401776083964, "SPIKEVAX": 1.0559009487660371, "TOZINAMERAN": 0.4073323676422714, "VAXZEVRIA": 1.4167890878845175, "ZYPREXA": 2.0007899326893392, "null": 0.7485504062149665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8332.json
index 4059f7d513a..14a1eea5473 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8332.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8332.json
@@ -1 +1 @@
-{"DAPAGLIFLOZIN": 419.682493202819, "SILDENAFIL": 46.70673341204428, "ZOSTAVAX": 56.273148011420645}
\ No newline at end of file
+{"null": 0.5421702344923595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8333.json
index 0ca15d1e066..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8333.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8333.json
@@ -1 +1 @@
-{"null": 1.2232456255414466}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8334.json
index dd5f1bc8fb2..330a056bcdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8334.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8334.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0592395894825684, "COVID19": 3.39022668643998}
\ No newline at end of file
+{"TAGRISSO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8335.json
index c2f973bcd29..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8335.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8335.json
@@ -1 +1 @@
-{"FAMPYRA": 199.91001590493025}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8336.json
index c5d81c6cec3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8336.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8336.json
@@ -1 +1 @@
-{"AFINITOR": 2.53925596295972, "AMINOSALICYLIC": 1.4890048765146149, "ANAKINRA": 5.846560033257857, "AVASTIN": 2.041510679289038, "AZATHIOPRINE": 2.9505975248937943, "BENLYSTA": 1.8498704292582293, "BOSULIF": 5.0678119604874485, "BOSUTINIB": 18.545509613748127, "BYETTA": 1.1460868440756151, "CABOMETYX": 1.939959513092802, "CELLCEPT": 1.1408052671347215, "CICLOSPORIN": 4.371180005063804, "CIMZIA": 1.1993047717582772, "CLOPIDOGREL": 1.9353832098736825, "COSENTYX": 1.665155700943748, "EFAVIRENZ": 5.465337607230384, "ELIQUIS": 2.1132407000417364, "ENBREL": 9.36579048076389, "ENTYVIO": 4.879298707354844, "ESBRIET": 1.4229369583471063, "EXFORGE": 2.2234445772559046, "EXJADE": 3.0102400110794845, "HUMIRA": 4.788352124919284, "IBRANCE": 1.0399381230689857, "IMIQUIMOD": 44.77487349557784, "INSULIN": 1.1792620122087514, "JAKAVI": 3.670730654767126, "JANUMET": 1.0673722807155102, "JANUVIA": 1.545783705415203, "LANTUS": 1.506811556391613, "METHOTREXATE": 1.2423945039065498, "NEXAVAR": 1.3666896657539316, "OPTIMARK": 2.368667764915237, "PLAVIX": 4.05031424190119, "RINVOQ": 5.353798710246716, "ROACTEMRA": 1.5459404677017974, "SIMPONI": 1.0306447974430044, "STELARA": 1.5689836141106948, "SUBOXONE": 1.3530044236199883, "SUTENT": 1.858934453868748, "TASIGNA": 2.170221532082966, "TRACLEER": 1.1938341810944646, "VOTRIENT": 1.356946678642695, "XELJANZ": 2.081045508166849, "ZOSTAVAX": 1.2911028137302425, "null": 1.1986962812163613}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8337.json
index 5824fb72d49..f8b6779523c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8337.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8337.json
@@ -1 +1 @@
-{"ADALIMUMAB": 4.077708178465914, "CLOPIDOGREL": 1.7709233173708214, "CYMBALTA": 1.23064766001478, "ELIQUIS": 4.852543782694105, "ENBREL": 1.4102738775656602, "FIRDAPSE": 5.150840792644057, "IBUPROFEN": 1.6849492003156077, "OPSUMIT": 1.2088807959948038, "PLAVIX": 231.8802514471334, "XARELTO": 3.3207938069000185, "XELJANZ": 1.2207001559744317}
\ No newline at end of file
+{"KEYTRUDA": 5.222949048736446, "SUTENT": 3.580632308906661, "null": 0.7938496878507377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8338.json
index 712dd626728..2626bc15737 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8338.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8338.json
@@ -1 +1 @@
-{"null": 2.0925266228089137}
\ No newline at end of file
+{"VOTRIENT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8339.json
index 1ffebc51a08..0887a172907 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8339.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8339.json
@@ -1 +1 @@
-{"null": 1.359417735449565}
\ No newline at end of file
+{"AIMOVIG": 0.8347717095316788, "ALEMTUZUMAB": 2.563630173294541, "CICLOSPORIN": 1.4158981235670511, "COMIRNATY": 0.5233715839252895, "CYMBALTA": 1.5739830874187133, "FENTANYL": 3.4932271309965577, "GARDASIL": 2.010269425713638, "HUMIRA": 2.1563249079890223, "IBUPROFEN": 2.097273707735886, "KALETRA": 2.1669161765653526, "KEPPRA": 2.1593419390961315, "LACOSAMIDE": 16.354456111143946, "LEVETIRACETAM": 3.8141550270278377, "MIDAZOLAM": 18.001340418123906, "PEGINTRON": 0.7913798198539647, "SPIKEVAX": 0.1913942576955003, "TOZINAMERAN": 0.4799437232706148, "TWINRIX": 3.983724362663025, "VAXZEVRIA": 0.2372024822920356, "VIMPAT": 7.102562501107253, "null": 2.837924128497023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/834.json
index d616075c562..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/834.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/834.json
@@ -1 +1 @@
-{"null": 1.1647388436024968}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8340.json
index f88551d85f4..7f4cddd24d1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8340.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8340.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 4.965966507886051, "EYLEA": 7.643840467955442, "NEPAFENAC": 642.186582802253, "NEVANAC": 439.7300494493194, "PEGASYS": 1.9113135751562025, "ROACTEMRA": 7.244791505876638, "TOBRAMYCIN": 48.27170811765266, "XELJANZ": 1.55582800175094, "ZOSTAVAX": 2.4644074591980454, "null": 1.6313223829197765}
\ No newline at end of file
+{"ABATACEPT": 11.23174663510611, "ABILIFY": 33.16537302849077, "ADALIMUMAB": 7.523767792424784, "AMINOSALICYLIC": 2.858997403932905, "ANAKINRA": 7.5839760883177885, "APIXABAN": 17.238254708969063, "APREMILAST": 6.346264408954157, "ARAVA": 0.6489532165730123, "ARIPIPRAZOLE": 24.235245202623183, "ATRIPLA": 0.0667365930783356, "AVANDIA": 0.5425948635917235, "BIKTARVY": 3.6439446922268695, "BUPRENORPHINE": 0.6422587538993758, "BYDUREON": 1.9464633834462863, "BYETTA": 1.9431017227512324, "CANAGLIFLOZIN": 19.671874272019515, "CELLCEPT": 0.9473206642216364, "CICLOSPORIN": 0.5638728660534578, "CIMZIA": 0.7996158909927176, "COMIRNATY": 0.0358729821796073, "COSENTYX": 3.357548525790007, "CYMBALTA": 0.7195508132407464, "DAPAGLIFLOZIN": 17.28763761920976, "DULOXETINE": 1.7067720522995695, "ELIQUIS": 0.9934679787893708, "ENBREL": 1.850763572368996, "ENTRESTO": 0.5237507596457698, "EXFORGE": 1.296149179494965, "FASENRA": 1.120227902336328, "FENTANYL": 0.569112217396537, "FORXIGA": 0.7696188556911921, "GARDASIL": 0.915974519119678, "GLYCOPYRRONIUM": 66.4218957243778, "HUMALOG": 1.480444706773789, "HUMIRA": 0.6822605363990816, "IBUPROFEN": 0.805062812324363, "INSULIN": 0.8450041330791419, "INVEGA": 38.05853944663191, "INVOKANA": 4.619202327250742, "IRON": 4.843594490924652, "JANUMET": 1.274331995772364, "JANUVIA": 1.4642564100232485, "JARDIANCE": 0.4753991481799808, "KEPPRA": 0.36484550300037, "KEYTRUDA": 0.2711512839826261, "LANTUS": 0.7413331668295274, "LATUDA": 4.261541041772467, "LEVETIRACETAM": 0.588108302585807, "LYRICA": 2.047288944678132, "MEPOLIZUMAB": 1.6388393411589153, "METHOTREXATE": 5.796785753980992, "OLANZAPINE": 5.668358845058338, "PLAVIX": 0.3923832477649318, "RISPERIDONE": 5.738143285086417, "SHINGRIX": 0.4661558415722667, "SPIKEVAX": 0.0515945634115512, "TASIGNA": 1.830192839936053, "TREMFYA": 1.5762866410258964, "TRULICITY": 1.2101192533087202, "VAXZEVRIA": 0.0167028747175563, "XELJANZ": 0.4177953697978061, "XOLAIR": 0.6738956539315443, "ZOSTAVAX": 15.276376542745435, "ZYPREXA": 15.727893569764973, "null": 0.7155874877088282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8341.json
index 906afef5ae6..668c7c1230e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8341.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8341.json
@@ -1 +1 @@
-{"ATRIPLA": 18.301690014399345, "STRIBILD": 12.727599742554318, "TRUVADA": 9.286609988380077}
\ No newline at end of file
+{"ABACAVIR": 13.102626038528143, "BUSULFAN": 29.519942099603245, "CELLCEPT": 6.972923364507349, "CICLOSPORIN": 45.6657529830442, "ENBREL": 22.287584952359467, "null": 0.8032172860532077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8342.json
index 98786e1331f..b169e4e244a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8342.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8342.json
@@ -1 +1 @@
-{"CYMBALTA": 10.630785699264049, "MIRABEGRON": 918.679257440768}
\ No newline at end of file
+{"ARSENIC": 438.63740015950617, "BRINTELLIX": 8.212337002231926, "CHAMPIX": 14.796793945329526, "CYMBALTA": 5.033858318680031, "DULOXETINE": 21.592823000036383, "KEPPRA": 3.8917112871652857, "LATUDA": 19.337806689170385, "OLANZAPINE": 6.923958139909304, "ZYPREXA": 9.106373952905454, "null": 2.236171548220756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8343.json
index 4661f55b95b..d9ec672e290 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8343.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8343.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3415661888751484}
\ No newline at end of file
+{"ABILIFY": 73.14962168574883, "ARIPIPRAZOLE": 117.35073665388713, "AVAMYS": 4.972689744861666, "AZILECT": 46.797422012772095, "CHAMPIX": 2.287928930852209, "COMIRNATY": 0.0194143631213901, "CYMBALTA": 0.7295304823109366, "DULOXETINE": 5.973045318394958, "GARDASIL": 2.858695349858913, "KEPPRA": 2.484732756833701, "LATUDA": 4.327155416712492, "LEVETIRACETAM": 1.9728031751093449, "LEVODOPA": 14.00328034366333, "OLANZAPINE": 11.01566196086666, "SIFROL": 20.97054602236829, "TRUVADA": 0.2737170804236412, "XYREM": 5.763962290003075, "ZYPREXA": 4.350587210559445, "null": 1.8279091330573212}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8344.json
index dabe268d875..49013ec5886 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8344.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8344.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2038606629257822}
\ No newline at end of file
+{"null": 1.5240291978744718}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8345.json
index b0537d2dbc0..0db09f7ce55 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8345.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8345.json
@@ -1 +1 @@
-{"null": 1.561918659840594}
\ No newline at end of file
+{"ARIPIPRAZOLE": 36.53754697222513, "OLANZAPINE": 47.47554614929604, "null": 1.610501395542247}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8346.json
index 6650d88f8cd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8346.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8346.json
@@ -1 +1 @@
-{"SPIKEVAX": 9.24490278161382}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8347.json
index 3230744923a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8347.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8347.json
@@ -1 +1 @@
-{"SPIKEVAX": 5.154628377720705}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8348.json
index 181e54f87c6..977ca89d62a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8348.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8348.json
@@ -1 +1 @@
-{"EFAVIRENZ": 646.4873303681012}
\ No newline at end of file
+{"null": 1.2685970754618725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8349.json
index e4b2652f84c..d19df666dca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8349.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8349.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"ACLIDINIUM": 37.10626431864435, "ADALIMUMAB": 0.5845783410381726, "ALENDRONATE": 652.4529975226078, "ANORO": 14.585760046753316, "APIXABAN": 55.08646100755898, "AVANDIA": 7.250883023933782, "AZATHIOPRINE": 8.066991343407365, "COMIRNATY": 0.1126155437844043, "ELIQUIS": 3.5510647647921494, "HUMIRA": 7.593318383881071, "MEPOLIZUMAB": 13.5181407418361, "null": 0.7904958023784738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/835.json
index dbcf69189bd..9f2111490f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/835.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/835.json
@@ -1 +1 @@
-{"AUBAGIO": 23.603536722744007, "COMIRNATY": 1.5859512585792312}
\ No newline at end of file
+{"null": 3.0355547077722944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8350.json
index aa58213a182..7b490b61e6c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8350.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8350.json
@@ -1 +1 @@
-{"COMBIVIR": 191.76965600620247, "null": 1.2383393565278067}
\ No newline at end of file
+{"BYETTA": 31.22489130869108, "JANUVIA": 11.244190319169984, "null": 1.8371004854383493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8351.json
index 01b7fb3d4a8..f8f64522dab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8351.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8351.json
@@ -1 +1 @@
-{"null": 1.403295159162802}
\ No newline at end of file
+{"ACLIDINIUM": 38.78514261709207, "ALENDRONATE": 78.8709776157945, "ANORO": 67.17227073171374, "APIXABAN": 16.495770309799674, "AVAMYS": 36.808893796529496, "AZATHIOPRINE": 4.06952300343254, "BENRALIZUMAB": 62.52144015713724, "BRIDION": 4.784842904081813, "BUDESONIDE": 36.59375227361463, "CANAGLIFLOZIN": 16.486138506290654, "CHOLESTAGEL": 55.82454169535375, "CICLOSPORIN": 0.6707587671804154, "CLOPIDOGREL": 1.1463588009523094, "COMIRNATY": 0.1321830725240824, "DAXAS": 81.25887567309145, "DEXAMETHASONE": 0.3784752208530477, "DUAKLIR": 145.00925102216425, "ELIQUIS": 0.5251220042654541, "ENTRESTO": 1.2782841731346075, "ENTYVIO": 0.7008524838228466, "ESOMEPRAZOLE": 2.0976777357808083, "FASENRA": 3.961407723116339, "FENTANYL": 3.5857170937508656, "FLUTICASONE": 54.21938165648433, "GLYCOPYRRONIUM": 44.02344786435396, "HIZENTRA": 1.7571328080751054, "HYDROCORTISONE": 1.56705161608354, "IBUPROFEN": 2.246851247486843, "INCRUSE": 4.522496775053304, "INVOKANA": 3.8711505949287215, "IRBESARTAN": 2.5180717189263224, "JANUMET": 1.067760341703888, "KEYTRUDA": 0.2517304345260305, "LEVOFLOXACIN": 0.8497445476988957, "LIRAGLUTIDE": 152.2367325114175, "MEPOLIZUMAB": 33.666128061621805, "METHOTREXATE": 3.390409058055038, "NAGLAZYME": 5.273498934977887, "NUCALA": 28.874289044793844, "OMALIZUMAB": 23.180545855912, "PANTOPRAZOLE": 6.990083199849857, "PREGABALIN": 6.276656146265909, "SPIKEVAX": 0.0859282303795083, "SYNAGIS": 3.121322617869412, "TOZINAMERAN": 0.2165797732786039, "TRELEGY": 1.3057337783290128, "UMECLIDINIUM": 33.240232575418496, "VAXZEVRIA": 0.0210438846623106, "XOLAIR": 5.655817256685253, "null": 0.9001507441427501}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8352.json
index 4683ff56107..498587b2be0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8352.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8352.json
@@ -1 +1 @@
-{"SPIKEVAX": 18.04575208717693}
\ No newline at end of file
+{"BYETTA": 34.13640529153494, "JANUVIA": 12.98287556480673, "SAXENDA": 26.32632903703612, "SPIRONOLACTONE": 53.390195120476776, "TRULICITY": 16.89917769749009, "VICTOZA": 50.02067307472699, "null": 0.4753868468198815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8353.json
index 9f28ea27ac5..13d988c01e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8353.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8353.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.7068822097092986, "null": 1.042236952025362}
\ No newline at end of file
+{"ABILIFY": 1.9607708968647013, "APIXABAN": 76.65292470283468, "BYDUREON": 2.549411232010367, "BYETTA": 7.292328161370191, "CHOLESTAGEL": 248.48900100341547, "CLOPIDOGREL": 2.38479002091944, "COMIRNATY": 0.1125431142985693, "CYMBALTA": 1.3462379242515443, "CYTARABINE": 2.724315726997285, "ELIQUIS": 1.3021697670249508, "GARDASIL": 0.8399294009754017, "IRBESARTAN": 34.4898290623038, "JANUMET": 7.482842983019616, "JANUVIA": 6.104547756404069, "MELATONIN": 13.337528545280822, "METHOTREXATE": 3.9927553532494464, "NAGLAZYME": 15.092124930041056, "SOMATROPIN": 93.44473712164935, "SPIKEVAX": 0.0991726067634252, "TESTOSTERONE": 27.240806841862785, "XYREM": 22.398941260294063, "ZOSTAVAX": 21.248253856330116, "ZYPREXA": 3.2927071125975385, "null": 0.6725558367345428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8354.json
index 43218ac3b38..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8354.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8354.json
@@ -1 +1 @@
-{"KEPPRA": 8.881756108754143, "RECOMBINANT": 5651.195571258748, "SUBOXONE": 14.445086620257037, "null": 1.5714114576288387}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8355.json
index 0d27f0b80ef..66830787061 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8355.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8355.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 15.315674338477075, "IRON": 116.6929442473178, "null": 1.7423991479673844}
\ No newline at end of file
+{"COMIRNATY": 2.055750108223561, "SHINGRIX": 6.806840554150423, "SPIKEVAX": 0.8389351782318198, "TOZINAMERAN": 3.086736075234053, "VAXZEVRIA": 0.8127106249093708, "ZOSTAVAX": 8.348965103768942, "null": 0.3039380649886273}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8356.json
index 885cd7e549a..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8356.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8356.json
@@ -1 +1 @@
-{"null": 1.3429555258382595}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8357.json
index 331b2c7aca9..cfac1dec3ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8357.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8357.json
@@ -1 +1 @@
-{"null": 1.5181316256520312}
\ No newline at end of file
+{"CLOPIDOGREL": 11.71990281399106, "COSENTYX": 8.703921515847151, "ELIQUIS": 18.32284486888121, "null": 1.509653168678026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8358.json
index e22e038ed2d..7ddbbd4dc00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8358.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8358.json
@@ -1 +1 @@
-{"BYETTA": 8.505569508829964, "JANUMET": 8.967303554201997, "JANUVIA": 6.656263467274217, "KEPPRA": 2.111714174555979, "LONSURF": 13.986086143251596, "METHOTREXATE": 3.0947730936955984, "NAGLAZYME": 23.40009916876121, "STELARA": 2.583810603874916, "SYNAGIS": 8.953664599720785, "ZOSTAVAX": 4.25179769911184, "null": 2.0762885789851726}
\ No newline at end of file
+{"ADCIRCA": 22.21482856195279, "ARANESP": 2.7445700887351063, "CLOPIDOGREL": 45.32851017641858, "COMIRNATY": 0.0397155584180322, "ELIQUIS": 5.928825435041823, "ENOXAPARIN": 18.83725540298517, "EXJADE": 4.245833867728391, "PLAVIX": 23.0867056231374, "ROTATEQ": 14.636764576177596, "TICAGRELOR": 35.740598372901744, "XARELTO": 9.944278996874278, "null": 1.097515067016658}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8359.json
index 37893bad9c3..71e9bbf3446 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8359.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8359.json
@@ -1 +1 @@
-{"ABILIFY": 2.7587993031230345, "ADENURIC": 5.751806739494086, "AIMOVIG": 1.4030490884372109, "AMINOSALICYLIC": 1.295549506097866, "ANORO": 1.276384623903611, "BEDAQUILINE": 10.686852435306, "BENLYSTA": 7.377874063480426, "BRAFTOVI": 7.040338454135608, "BRIDION": 7.1574894919712015, "BRINTELLIX": 4.336780606208564, "BRIVARACETAM": 5.9146100755234645, "BRIVIACT": 6.090769037701363, "BRUKINSA": 17.415428879345832, "BUPIVACAINE": 3.375362282083454, "BUPRENORPHINE": 1.935009785383908, "BYDUREON": 2.3256064290790737, "BYETTA": 1.1693750765132858, "CARBIDOPA": 7.5794908981817395, "DARZALEX": 1.978767099571325, "DELAMANID": 8.350310861689435, "ELIQUIS": 1.0089025313435844, "ENTRESTO": 7.808026541715906, "ENZALUTAMIDE": 6.262036910490101, "EVRA": 5.971975249478788, "FAMPYRA": 27.43747550550359, "FEBUXOSTAT": 4.828899641593568, "FORXIGA": 2.51625728458078, "GLUCAGON": 10.913071924340004, "HEMLIBRA": 4.63283956594904, "HUMALOG": 5.2565795328222205, "INCRUSE": 9.472191046330677, "JANUMET": 1.0890581576370846, "KEPPRA": 1.8578485072601232, "KEYTRUDA": 1.703447624632257, "LANTUS": 1.166320198606205, "LATUDA": 3.113041601358661, "LIXIANA": 7.08269592862228, "LYNPARZA": 1.1667494380995669, "LYRICA": 2.644347220793812, "MIMPARA": 11.165910865547437, "MULTAQ": 9.33628254728198, "ONCASPAR": 3.125211649446757, "PEGINTRON": 1.2639426588491027, "PEMBROLIZUMAB": 1.3685811019003749, "PLEGRIDY": 1.7531002373044269, "RANEXA": 7.858868622907402, "RELVAR": 1.6345629752147024, "ROTATEQ": 5.201048088896739, "RUBRACA": 11.124479474940012, "RUCONEST": 20.15351565744619, "SIMPONI": 12.771435580432549, "SPRYCEL": 1.16431095456629, "STELARA": 2.6275967751343385, "SUBOXONE": 11.486931876349562, "SYCREST": 4.4439306238259295, "TRELEGY": 3.1445070133208906, "TREMFYA": 18.58864933367332, "TWINRIX": 13.918380774975006, "VALSARTAN": 12.660336688721776, "VIMPAT": 3.126602007759616, "XARELTO": 1.4787541917151985, "XTANDI": 33.0552666161666, "null": 1.5489983450527225}
\ No newline at end of file
+{"null": 2.278058895532269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/836.json
index 7686580e6eb..43cf517febc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/836.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/836.json
@@ -1 +1 @@
-{"ROTATEQ": 2708.880104596388}
\ No newline at end of file
+{"ATRIPLA": 0.2334137442904709, "AVANDIA": 2.5261139334429763, "CICLOSPORIN": 1.2737966274388528, "CIMZIA": 0.7442708294824745, "CLOPIDOGREL": 2.361815470890023, "COMIRNATY": 0.1479256946264388, "ELIQUIS": 4.071991919971926, "ESBRIET": 6.3677091319236485, "EXFORGE": 6.873072114304232, "FORSTEO": 3.8968635724481535, "HUMALOG": 0.9224798598339436, "IRBESARTAN": 7.628220743712314, "JANUMET": 4.4939105479476575, "JANUVIA": 6.340050655965332, "KEYTRUDA": 0.9284436248493626, "LANTUS": 0.542194702765772, "OMALIZUMAB": 5.653587833466371, "PEGASYS": 0.7158668432094825, "PLAVIX": 4.923854520126811, "ROACTEMRA": 2.4127672812855714, "SPIKEVAX": 0.2261836609769257, "STELARA": 1.623950540927389, "SUTENT": 0.7373550650910752, "TASIGNA": 2.6647182610087445, "TESTOSTERONE": 18.17837141989954, "TOZINAMERAN": 0.3083423815611857, "VAXZEVRIA": 0.1389965800586333, "VIAGRA": 3.35385269780366, "XELJANZ": 2.0230702929289097, "ZOSTAVAX": 5.545072419856558, "null": 1.5220392872203234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8360.json
index 97b5f0e60b2..26b792e3afe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8360.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8360.json
@@ -1 +1 @@
-{"ATRIPLA": 8.116249260535712, "COMBIVIR": 15.18238783912946, "GARDASIL": 2.4842726759569738, "PEGASYS": 2.474092611415737, "TRUVADA": 1.7264158145518078}
\ No newline at end of file
+{"NOVORAPID": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8361.json
index a5d11c57dc5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8361.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8361.json
@@ -1 +1 @@
-{"ABILIFY": 53.00269818008081, "ATRIPLA": 12.338751234123718}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8362.json
index 8f4b6fd2ab7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8362.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8362.json
@@ -1 +1 @@
-{"ABILIFY": 1.1383126657870983, "ADEMPAS": 7.043618286334845, "ALL": 12.077456970166384, "AMBRISENTAN": 7.399869150646448, "APIDRA": 2.7757365196115167, "ARANESP": 3.0465677840202483, "AUBAGIO": 9.92809357359207, "AZACITIDINE": 2.290218840538167, "AZATHIOPRINE": 1.00230510985872, "BIKTARVY": 3.511134094175433, "BLINATUMOMAB": 8.185316307199333, "BRIVIACT": 2.3992235556479544, "BUPIVACAINE": 8.387640095625544, "BUPRENORPHINE": 1.3296764778347328, "CIMZIA": 1.8786921874230569, "CINRYZE": 6.106478130705123, "CYMBALTA": 1.2514061498831932, "ENBREL": 1.1250619240465265, "EVENITY": 7.291176011995714, "FENTANYL": 3.3215669157778365, "FIRDAPSE": 16.06641990265106, "HARVONI": 2.495931668685869, "HIZENTRA": 6.289373205270835, "HUMIRA": 3.974716538591281, "ICLUSIG": 3.4328042221818205, "INSULIN": 1.443374325612405, "KALETRA": 2.5818743854755954, "KEPPRA": 3.6788389546728366, "KYPROLIS": 2.8518232924438056, "LANTUS": 5.222064746174999, "LEMTRADA": 3.5096739426359003, "LYRICA": 1.7631496601701375, "MELATONIN": 5.301688634526713, "MEPOLIZUMAB": 2.07475202496778, "MIMPARA": 4.113144049503172, "MULTAQ": 1.661696286468244, "NEULASTA": 5.147706161421242, "NPLATE": 3.153059293777298, "OFEV": 1.348167329507134, "OLYSIO": 1.8877049561451027, "OPSUMIT": 8.768845752746968, "PEGASYS": 1.0549387338203535, "PEGINTERFERON": 1.1348846758881526, "PRIVIGEN": 2.044782742019027, "RANOLAZINE": 12.18475737516159, "REVLIMID": 2.471308435465004, "RIBAVIRIN": 3.18860014779985, "RINVOQ": 6.675917046014343, "RUBRACA": 1.7186387287468052, "SKYRIZI": 14.657310260828504, "SOLIRIS": 3.083328262944219, "SOVALDI": 2.45048167784442, "SUBOXONE": 3.33812182149973, "SYNAGIS": 31.67530204354482, "TERIFLUNOMIDE": 7.398559640031065, "TOUJEO": 6.197248355539708, "TOVIAZ": 2.53481196005712, "TRACLEER": 2.724870025667716, "TUKYSA": 62.01537255047938, "VELTASSA": 3.6204475883416447, "VENCLYXTO": 5.588489032890303, "VENETOCLAX": 7.551283964943294, "VIAGRA": 1.1246650999333987, "VIMPAT": 1.1968791977641298, "VIREAD": 1.0362490613230229, "XTANDI": 1.2644519409236934, "XYREM": 17.527563031262044, "null": 1.333028028525026}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8363.json
index 8cc721c4a7e..d25e3925140 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8363.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8363.json
@@ -1 +1 @@
-{"COMIRNATY": 6.407483561201405}
\ No newline at end of file
+{"COMIRNATY": 0.0559376375932337, "QUTENZA": 1538.1797386052046, "ZOSTAVAX": 3.232122886757363, "null": 1.833262466937684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8364.json
index 758c50e7094..63a755acd72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8364.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8364.json
@@ -1 +1 @@
-{"CHAMPIX": 1.1712294878789546, "ELLAONE": 1534.5004909373415, "EVRA": 727.267258337259, "KEPPRA": 9.379003548344048, "null": 1.5240256692213598}
\ No newline at end of file
+{"RITUXIMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8365.json
index 963bb130e08..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8365.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8365.json
@@ -1 +1 @@
-{"NEULASTA": 2200.817635316378}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8366.json
index db0a782c970..3ccf971f39a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8366.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8366.json
@@ -1 +1 @@
-{"null": 1.2477555428486908}
\ No newline at end of file
+{"ADALIMUMAB": 0.7952720934906011, "AIMOVIG": 0.5689351110400936, "AVAMYS": 2.230543649968372, "BEOVU": 18.85339119830556, "BUDESONIDE": 0.3972482939340597, "CHAMPIX": 0.4544717457070206, "COMIRNATY": 1.866071036574106, "COSENTYX": 1.668481651705456, "CYMBALTA": 4.162140869780567, "ELIQUIS": 0.3060747368967885, "EYLEA": 11.368129053437722, "GARDASIL": 0.2658105092272456, "HUMALOG": 0.4678123801178415, "IKERVIS": 33.26831969137706, "KAFTRIO": 2.4266699517965944, "LANTUS": 0.3486112268016694, "MEPOLIZUMAB": 14.65765996492672, "NEVANAC": 19.42386459040564, "NUCALA": 4.523893455464834, "PEGINTRON": 0.4761744140959809, "SHINGRIX": 0.9554730347946404, "SPIKEVAX": 1.690217525096201, "TOZINAMERAN": 1.312525585977396, "VAXZEVRIA": 1.4796692347200198, "VFEND": 0.9049406013956344, "VIAGRA": 1.5140359606051352, "XELJANZ": 0.3425637257071931, "XOLAIR": 0.4360800139291456, "ZOSTAVAX": 0.433092063503781, "null": 0.7071665628166621}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8367.json
index 1b586bb0fed..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8367.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8367.json
@@ -1 +1 @@
-{"null": 2.3437301815919573}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8368.json
index 90f791c6913..bcee1b2eab9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8368.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8368.json
@@ -1 +1 @@
-{"LACOSAMIDE": 91.91817135707836, "null": 2.0204132437341378}
\ No newline at end of file
+{"AFINITOR": 0.3841561816218114, "AIMOVIG": 0.4943299933886462, "APIDRA": 0.4633896994329465, "AVAMYS": 0.8287206643163291, "AVASTIN": 0.6508133853315914, "BENLYSTA": 0.7110918073796287, "BEOVU": 37.57471454772128, "BRAFTOVI": 0.8508720790200922, "BRILIQUE": 0.6768411285117376, "BRIMONIDINE": 30.48440017252974, "BRINTELLIX": 0.3685254032295129, "BROLUCIZUMAB": 62.23780902167999, "BUDESONIDE": 0.2600366990752122, "CHAMPIX": 0.9149854305873631, "CICLOSPORIN": 0.2890412669047333, "CIMZIA": 0.4215917848231161, "CLOPIDOGREL": 0.7763749224588566, "COMIRNATY": 0.7448816357005836, "COSENTYX": 1.7509440609389768, "CYMBALTA": 0.1710131112195115, "DEXAMETHASONE": 1.2808976201849391, "ELIQUIS": 0.9777477120638386, "ENBREL": 0.7325159374892299, "ENTRESTO": 0.4640758200181262, "ENTYVIO": 0.4065185514325269, "EXFORGE": 1.445698266822597, "EXJADE": 0.3070896125360609, "EYLEA": 16.4719984241656, "FASENRA": 0.6166304107723131, "FASLODEX": 0.4390518054555648, "FENTANYL": 0.3440596809054081, "FLUTICASONE": 5.450937861083248, "FORSTEO": 0.4204729472342415, "FORXIGA": 0.6530813348678124, "GARDASIL": 0.6584542687908963, "HUMALOG": 0.2181039367312381, "HUMIRA": 0.7960833445593102, "HYDROCORTISONE": 1.0290968923917447, "IBRANCE": 0.3458611537018295, "IKERVIS": 83.92988741684864, "IRBESARTAN": 1.3588079402220776, "IRESSA": 0.7752314931037404, "JETREA": 13.713770737041854, "KALETRA": 0.7537908562138737, "KEPPRA": 0.2405814317737525, "KEYTRUDA": 0.4420164671652664, "LANTUS": 0.4525213930012997, "LEVOFLOXACIN": 0.4902059505296622, "MEKINIST": 1.3700625021470192, "MELATONIN": 1.5525523366322944, "MEPOLIZUMAB": 6.110236397886297, "METHOTREXATE": 0.3651664518899645, "MMRVAXPRO": 1.037642973368995, "NEPAFENAC": 52.03467092134263, "NEVANAC": 36.290202634937856, "NIMENRIX": 1.0362348213245964, "NUCALA": 2.011637721448344, "OMALIZUMAB": 1.3959991518592016, "OPATANOL": 43.74035806725436, "OPSUMIT": 0.7913973466601244, "OPTIMARK": 0.3954839762824707, "PEGASYS": 0.9107331124786188, "PEGINTRON": 0.5511461385017092, "PLAVIX": 0.7203989532799565, "RINVOQ": 1.0002213031467386, "RITUXIMAB": 1.1127567182089926, "SHINGRIX": 1.1676149783428662, "SILDENAFIL": 1.108199251407869, "SIMPONI": 0.4198073201278534, "SPIKEVAX": 0.6214564054420905, "SPRYCEL": 0.5042028209663599, "STELARA": 0.3113854297553519, "SUTENT": 0.7447409219379281, "TAGRISSO": 0.8601021430363724, "TAMIFLU": 1.8254463987836704, "TASIGNA": 0.4748604153132013, "TOBRAMYCIN": 6.195404658368457, "TOVIAZ": 0.8850003592659647, "TOZINAMERAN": 1.3802969645479015, "TRELEGY": 1.2677824841362135, "VAXZEVRIA": 0.8986351454299925, "VFEND": 0.5923737557795824, "VIAGRA": 2.5504874357382774, "XELJANZ": 0.5707116565377314, "XOLAIR": 1.048145272635969, "ZELBORAF": 2.432905770960995, "ZOSTAVAX": 0.6149141130271754, "null": 1.7722012088516763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8369.json
index 39f3aac76ef..2bbb76cf282 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8369.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8369.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 1.0410658819562415, "ASPARAGINASE": 1.4218659937561149, "BENZODIAZEPINE": 4.995510704232264, "BEXSERO": 9.055974891140345, "BRIDION": 1.736758918385895, "BUPIVACAINE": 8.090250159834946, "BUPRENORPHINE": 3.654478409210671, "CASPOFUNGIN": 3.5960029992679075, "CELECOXIB": 9.024377805968376, "CERTAGEN": 466.9616320756938, "DAPAGLIFLOZIN": 5.1840069411430045, "DULOXETINE": 1.683719024048224, "ENOXAPARIN": 1.2322534650911752, "ESOMEPRAZOLE": 2.403354240811701, "EXJADE": 1.157909449171209, "FENTANYL": 11.925569817864371, "FIRDAPSE": 1.9985994379761765, "GARDASIL": 3.2682859686038674, "GLIBENCLAMIDE": 9.77031366872226, "GLUCAGON": 5.312935100752528, "HEXYON": 6.37297324703269, "IBUPROFEN": 3.501804982344113, "INFANRIX": 5.445338220164914, "INSULIN": 3.919987084233172, "INTEGRILIN": 7.2337051250587505, "KEPPRA": 1.9546000091396185, "LACOSAMIDE": 2.656981468627845, "LEVETIRACETAM": 2.125079441636542, "LEVOFLOXACIN": 1.2164341816387854, "LYRICA": 1.17929360776368, "MENVEO": 3.3443448879763653, "MIDAZOLAM": 9.047745310812244, "MIRCERA": 36.19180842117902, "MMRVAXPRO": 1.329041459007961, "NAGLAZYME": 1.9137587402244929, "NALOXONE": 53.956637931813454, "NIMENRIX": 2.323760919784596, "NOT": 1.989702721451964, "OLANZAPINE": 4.835882599316331, "PREGABALIN": 4.056920614478486, "PREVENAR": 6.618483593562401, "PRIALT": 30.15673968952885, "PRIVIGEN": 1.6624896619616467, "PROPRANOLOL": 6.760882583586129, "ROTARIX": 19.37607921844701, "ROTATEQ": 3.656149158110854, "SPIKEVAX": 1.0217189906804052, "SPINRAZA": 1.1262589191565484, "SUBOXONE": 4.271070394690093, "SYNAGIS": 1.8862414731107469, "TRACLEER": 1.0496964889040137, "VELTASSA": 1.869062516703759, "VIMPAT": 1.099721737396595, "VORICONAZOLE": 1.3815793315975151, "XYREM": 1.5289889582791991, "ZYPADHERA": 7.946171076445163, "ZYPREXA": 1.372658731139145, "null": 2.277073976066646}
\ No newline at end of file
+{"COMIRNATY": 0.7073786880512686, "EYLEA": 86.2064115385778, "SPIKEVAX": 0.4062332033063415, "VAXZEVRIA": 0.2807822159354735, "ZOSTAVAX": 4.580785043272464, "null": 1.365793704462357}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/837.json
index 6bb7d67e9b3..6f1ec2f3cdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/837.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/837.json
@@ -1 +1 @@
-{"ANAKINRA": 647.1328900046018}
\ No newline at end of file
+{"null": 1.710304764804888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8370.json
index c57a30da86a..6115705af38 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8370.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8370.json
@@ -1 +1 @@
-{"FENTANYL": 119.16569296340666, "MIDAZOLAM": 112.9254495135968, "null": 2.735554988190805}
\ No newline at end of file
+{"ARAVA": 0.285620644860528, "ATAZANAVIR": 11.08706605602628, "BUPRENORPHINE": 1.977225414820332, "COMIRNATY": 0.0844383058012867, "CYMBALTA": 1.3939003072775076, "EXJADE": 4.793531916887997, "EXVIERA": 14.675267961757802, "LEVOFLOXACIN": 2.9348030067304824, "NEXAVAR": 3.0906704393524307, "NORVIR": 41.01902061840364, "OCALIVA": 16.88078745165721, "OPTIMARK": 8.606465085381101, "PEGASYS": 1.0436888665296575, "REYATAZ": 162.10864387129527, "SOLIRIS": 3.673485958480167, "SPIKEVAX": 0.0593198425554833, "STIVARGA": 8.2514143042709, "SUBOXONE": 2.5440398806498683, "SUTENT": 1.3975558018064989, "TRACLEER": 3.8830844366291073, "TWINRIX": 7.527489952226493, "VAXZEVRIA": 0.0454350170914749, "null": 1.823314041484222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8371.json
index 08c813c6598..76005f9c027 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8371.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8371.json
@@ -1 +1 @@
-{"EVRA": 1551.6748132401951}
\ No newline at end of file
+{"null": 1.0060728874517513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8372.json
index 5b07eb2451e..79aeb33dde2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8372.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8372.json
@@ -1 +1 @@
-{"BRIDION": 32.20391208796593, "DEXMEDETOMIDINE": 240.49301258016715, "FENTANYL": 28.21591087237004, "XOLAIR": 19.60295950321052, "null": 1.4481540223478988}
\ No newline at end of file
+{"COMIRNATY": 1.5895773901909855, "KEYTRUDA": 11.79291697130396, "PEMBROLIZUMAB": 45.9761589140098, "null": 0.2930566020655578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8373.json
index 33224ef827b..963326d1a49 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8373.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8373.json
@@ -1 +1 @@
-{"APIXABAN": 1.827993225765113, "BORTEZOMIB": 5.476847539489917, "BRILIQUE": 6.997420650254858, "BUDESONIDE": 1.0484083389755958, "CAPECITABINE": 1.3770548481589846, "CELECOXIB": 2.533230213714392, "CLOPIDOGREL": 88.80658327964588, "DEFITELIO": 16.253181953656846, "EBIXA": 5.841939044505608, "EFIENT": 14.177910592421725, "ELIQUIS": 7.755502830533035, "ENOXAPARIN": 33.35345022945278, "HARVONI": 2.9747165137114364, "IBUPROFEN": 4.404948008030238, "JAKAVI": 1.177185458491286, "LENVIMA": 2.0740997562694945, "LIXIANA": 9.888523175927004, "NEXAVAR": 2.696728308867445, "PLAVIX": 34.89233105922272, "PRADAXA": 9.404583033498373, "PRASUGREL": 19.26522008686017, "RIVAROXABAN": 8.643328108856178, "SOVALDI": 2.09455964634024, "TICAGRELOR": 123.53121169706012, "XARELTO": 38.24743968432063}
\ No newline at end of file
+{"null": 0.9883776974219816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8374.json
index 30a06a054ae..de7cf18c0cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8374.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8374.json
@@ -1 +1 @@
-{"ANAKINRA": 1.7660956293031682, "APIDRA": 1.4361175728186697, "ATRIPLA": 8.624920736524158, "AVANDIA": 1.435790218649063, "BENRALIZUMAB": 71.24065781732918, "CIMZIA": 1.2835809583172766, "ELIQUIS": 1.894983197920358, "ENBREL": 1.2249363319660869, "ESBRIET": 1.4202893261486054, "EVENITY": 7.887001755859747, "EVISTA": 4.955706561828708, "EXFORGE": 2.4993057898153523, "FAMPYRA": 3.574884307683732, "FORSTEO": 8.501288982942949, "HUMALOG": 2.146620976444429, "HUMIRA": 1.2970645175762572, "IBRANCE": 3.9486453295592447, "INOVELON": 74.45402310349861, "JANUVIA": 1.2564143858244423, "KALETRA": 4.229969470959063, "LANTUS": 3.18450455080312, "LYRICA": 2.950091569427575, "OPSUMIT": 1.2378254416176395, "ORKAMBI": 4.906698835782488, "REVATIO": 4.382217096822105, "RITUXIMAB": 2.6420945475793345, "SIMPONI": 3.054501344071998, "STRIBILD": 6.600377437949353, "SUBOXONE": 4.540865846237788, "TERIPARATIDE": 19.51463055554854, "TRELEGY": 1.6507375828280724, "TRUVADA": 7.461123161694659, "VIAGRA": 1.3586131588445591, "VIREAD": 2.5726813399254023, "XELJANZ": 5.47997362201795, "XOLAIR": 2.070160168182349, "XTANDI": 3.156395475389211, "null": 1.013879295144023}
\ No newline at end of file
+{"null": 1.09168592872367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8375.json
index d6fc00e766c..2ef3167a3b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8375.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8375.json
@@ -1 +1 @@
-{"BUDESONIDE": 202.2940538877336}
\ No newline at end of file
+{"EYLEA": 610.573408963839, "null": 0.4268472894223336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8376.json
index 774d920d87d..40a69ecab42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8376.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8376.json
@@ -1 +1 @@
-{"ESBRIET": 12.127159172464966, "NUCALA": 6.57909633302121, "TOZINAMERAN": 3.521983355175164, "XELJANZ": 3.7915813868841135, "XOLAIR": 4.333657040116179, "null": 1.5085709698951235}
\ No newline at end of file
+{"null": 1.271452995404746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8377.json
index 79bf59211e4..c0fb661ef41 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8377.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8377.json
@@ -1 +1 @@
-{"ABACAVIR": 68.09805521754512, "ABATACEPT": 1.146742480032284, "ACLIDINIUM": 5.824487494924433, "AMINOSALICYLIC": 1.7528487481527688, "ATEZOLIZUMAB": 4.91300134148857, "AUBAGIO": 1.372734262680528, "AVAMYS": 3.0503914026203462, "AZATHIOPRINE": 4.36603488519, "BENLYSTA": 2.275161673522448, "BORTEZOMIB": 1.8257046124718057, "BUDESONIDE": 1.4801920247202125, "BUSULFAN": 1.8751613258176056, "CARFILZOMIB": 2.0288176340708763, "CELLCEPT": 1.5874918783021856, "CICLOSPORIN": 1.2494145845086084, "CIMZIA": 2.692425945512653, "COMBIVIR": 1.2907046725223434, "COSENTYX": 2.8060854575602976, "CYTARABINE": 2.310943791498685, "DARATUMUMAB": 5.713232229876285, "DARZALEX": 2.3404623862602683, "DESLORATADINE": 3.449905412019484, "DEXAMETHASONE": 1.7831119544895262, "ENBREL": 6.038068296926785, "ESBRIET": 1.2949399811381264, "EVISTA": 1.4327042465811988, "EXJADE": 1.1672694447905194, "FASENRA": 1.410367734934696, "FILGRASTIM": 1.6792109092419063, "GARDASIL": 1.321325692619287, "HIZENTRA": 8.368358491661287, "HUMAN": 1.0749954932632435, "HUMIRA": 1.9181325013211523, "IBRANCE": 1.151718200414669, "IBUPROFEN": 2.284212370149188, "INCRUSE": 1.8684551187799692, "INSULIN": 5.101732254187432, "JANUVIA": 1.182111461768301, "KESIMPTA": 2.434798065387689, "KYPROLIS": 2.0821663667857635, "LEFLUNOMIDE": 6.516649905179939, "MAVENCLAD": 4.740294137978795, "MENVEO": 2.9832453852425265, "MEPOLIZUMAB": 5.223758101595506, "MERCAPTOPURINE": 3.0415188096971173, "METHOTREXATE": 1.3174752959837015, "MMRVAXPRO": 2.375498359674113, "NAGLAZYME": 3.5069433582323035, "NINLARO": 2.1587438697775645, "NOT": 1.1442296235184986, "NPLATE": 1.3084765218286212, "NUCALA": 3.2238681238271245, "OMALIZUMAB": 3.777376695465296, "OPSUMIT": 2.725388298052311, "ORENCIA": 21.531977178920023, "ORKAMBI": 2.2518345110030458, "PREVENAR": 4.000349251026849, "PRIVIGEN": 1.7117962151037778, "REVLIMID": 1.9626175982856564, "RINVOQ": 2.8972700512679066, "RITUXIMAB": 1.4276508986935412, "ROACTEMRA": 3.0111873986057134, "ROTATEQ": 6.1183450931921, "RUCONEST": 4.706274534941705, "SIMPONI": 1.426779110735893, "SOLIRIS": 4.291966417716509, "SPINRAZA": 5.099917008781794, "SPRYCEL": 1.3771183796909725, "STELARA": 3.810089700823908, "SYNAGIS": 12.008213232847556, "SYNFLORIX": 36.55224574583768, "TOPOTECAN": 5.248301833835703, "TRACLEER": 2.6020171756417327, "TRELEGY": 1.9349714589882447, "TREMFYA": 4.530205566613515, "XELJANZ": 4.699784227846555, "XOLAIR": 3.282196683747181, "ZOSTAVAX": 3.064717013662638}
\ No newline at end of file
+{"ARAVA": 3.661593079593017, "BELANTAMAB": 2921.8518615322105, "COTELLIC": 93.4614007033173, "null": 0.5680848608211192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8378.json
index 365d5861017..188ef87fef1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8378.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8378.json
@@ -1 +1 @@
-{"ADEMPAS": 42.805849628433954, "CELLCEPT": 9.699140790352994, "ENTRESTO": 7.829788801541455, "SYNAGIS": 21.10220807567137, "null": 1.31081925603329}
\ No newline at end of file
+{"COMIRNATY": 0.591056829493474, "CYMBALTA": 3.611842414516485, "LANTUS": 3.721179044518842, "PEGASYS": 3.534021348166976, "SUTENT": 2.7693538044493304, "TOZINAMERAN": 4.092427122949177, "VIAGRA": 28.872690648385948, "null": 0.5101350019106208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8379.json
index 0ded08dfa51..41b579651a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8379.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8379.json
@@ -1 +1 @@
-{"null": 2.277577993366569}
\ No newline at end of file
+{"BEOVU": 577.9275414880514, "COMIRNATY": 0.5743899810103541, "EYLEA": 90.78846820066109, "null": 0.261566081877385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/838.json
index 5a4d608f82f..be521baba3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/838.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/838.json
@@ -1 +1 @@
-{"APREPITANT": 72.22825313802474, "BYETTA": 6.360285941665228, "HUMALOG": 3.39694587919068, "JANUMET": 4.858320255899075, "JANUVIA": 3.899518240351196, "PLAVIX": 5.1052873628851945, "ZOSTAVAX": 5.6029332567183205, "null": 2.624166962657097}
\ No newline at end of file
+{"COMIRNATY": 0.5946162027356916, "ELIQUIS": 3.8874011384393983, "null": 0.9574184563559076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8380.json
index 2807cc1f281..4d6f01073e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8380.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8380.json
@@ -1 +1 @@
-{"ACLIDINIUM": 17.52272997128199, "AVAMYS": 9.224396721177278, "BUDESONIDE": 78.61334216714505, "ENBREL": 1.6928975448992876, "GLYCOPYRRONIUM": 75.31106485651519, "IBRANCE": 3.036887642197566, "MEPOLIZUMAB": 21.72670457495433, "NUCALA": 64.30722268327983, "OMALIZUMAB": 4.975918776647061, "OPSUMIT": 2.71857782432244, "TIVICAY": 29.04998167215432, "TRELEGY": 3.5245183659369674, "VARENICLINE": 128.9794377523192, "XELJANZ": 1.5775400745168229, "XOLAIR": 4.361711039263777, "ZOSTAVAX": 3.990006224925632}
\ No newline at end of file
+{"null": 2.760938441528851}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8381.json
index e3767ce2399..769d7de26e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8381.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8381.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 154.98763315654847}
\ No newline at end of file
+{"ABILIFY": 28.59089182223291, "ARIPIPRAZOLE": 20.96218258056981, "COMIRNATY": 0.0429321971691569, "INVEGA": 29.93228050128501, "LATUDA": 89.49644459543752, "OLANZAPINE": 25.75054062010908, "ZYPREXA": 8.809218987364288, "null": 3.3554566582233454}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8382.json
index 9e0426b7f30..9db0118577f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8382.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8382.json
@@ -1 +1 @@
-{"null": 1.1188669398642743}
\ No newline at end of file
+{"COMIRNATY": 0.6170554016150102, "null": 4.6410790690197485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8383.json
index 5b4bdef9716..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8383.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8383.json
@@ -1 +1 @@
-{"FILGRASTIM": 64.22892884661363, "XTANDI": 7.205096110626176}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8384.json
index 98b32ef88a5..3537d69129f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8384.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8384.json
@@ -1 +1 @@
-{"CELLCEPT": 22.03720358569052, "CICLOSPORIN": 14.213455252192364}
\ No newline at end of file
+{"AFINITOR": 1.2552269943959016, "ALEMTUZUMAB": 5.651073042950182, "CELLCEPT": 0.9333714725236876, "CIMZIA": 0.433014909392269, "COMIRNATY": 1.7772087301594823, "COSENTYX": 1.05838480275248, "CYTARABINE": 1.627094622214856, "DEXAMETHASONE": 1.365758720710773, "ENTRESTO": 1.053203578563098, "GARDASIL": 0.8550943399328591, "IBRANCE": 0.9363462736547308, "IMATINIB": 9.10890464533019, "MEPOLIZUMAB": 1.3882389479934876, "MODERNA": 8.676878750232142, "NEXAVAR": 1.6656719671295566, "SPIKEVAX": 0.6091557684468804, "STIVARGA": 1.9806146176672623, "SUTENT": 1.752123670582482, "TASIGNA": 1.9222048352626329, "TOZINAMERAN": 2.6751279412134785, "VAXZEVRIA": 0.7498722044737408, "XALKORI": 3.7569855983701848, "null": 0.8519396446786905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8385.json
index 83a91473c6d..aa58535b0e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8385.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8385.json
@@ -1 +1 @@
-{"CRIXIVAN": 74.24484245035234, "null": 1.1696361539890086}
\ No newline at end of file
+{"ABACAVIR": 0.2721660993265883, "ABASAGLAR": 0.8630645104508645, "ABATACEPT": 0.8349351105400837, "ABILIFY": 0.1082756876324617, "ACTOS": 4.9641528571071785, "ADALIMUMAB": 1.9233467712343488, "ADCIRCA": 4.344012397501819, "ADEMPAS": 5.30380729086785, "AERIUS": 1.344497472390053, "AFINITOR": 2.3226709528494816, "AIMOVIG": 0.5063254956531075, "ALIMTA": 1.6564331694455512, "AMBRISENTAN": 4.846218519886903, "AMGEVITA": 15.39793789286796, "AMINOSALICYLIC": 0.8572586214946536, "APIDRA": 0.5039914149927477, "APIXABAN": 0.2528631664499205, "APREMILAST": 0.5359349765263978, "APROVEL": 1.067354843377424, "ARANESP": 0.7361567650390813, "ARAVA": 0.5320727756107256, "ASPARAGINASE": 0.3049012099932584, "ATAZANAVIR": 0.8360925843115875, "ATRIPLA": 0.0411044016653293, "AUBAGIO": 0.2511014492595629, "AVANDAMET": 2.3627474756270748, "AVANDIA": 5.649473610403978, "AVASTIN": 0.3657677802361412, "AZATHIOPRINE": 0.4497046643485111, "BEDAQUILINE": 1.1607565956339865, "BENLYSTA": 0.2438188521987309, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8386.json
index b2e7b6bb632..2b6f5b599e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8386.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8386.json
@@ -1 +1 @@
-{"null": 1.0903507378513329}
\ No newline at end of file
+{"null": 0.4905699579185362}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8387.json
index d28d6c5cce6..0d5ee1c5f5f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8387.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8387.json
@@ -1 +1 @@
-{"TIVICAY": 1037.6759625949808}
\ No newline at end of file
+{"null": 1.0836455511485923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8388.json
index c728e554c0c..52433b17a03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8388.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8388.json
@@ -1 +1 @@
-{"null": 1.6009160989364355}
\ No newline at end of file
+{"COMIRNATY": 0.1988882731943478, "JARDIANCE": 8.81291089974848, "null": 2.322333099411027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8389.json
index 555e008ce37..b2e655f1c8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8389.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8389.json
@@ -1 +1 @@
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\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/839.json
index b06c7f5682b..67fc7672309 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/839.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/839.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1019028534029207}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8390.json
index d4ccf3c855d..39ddbd5419a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8390.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8390.json
@@ -1 +1 @@
-{"null": 1.5866082288418275}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8391.json
index 9262a7da856..345f343827e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8391.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8391.json
@@ -1 +1 @@
-{"SUTENT": 8.151174145499338}
\ No newline at end of file
+{"null": 2.588873808515698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8392.json
index 564089a8877..9691c6eb6cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8392.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8392.json
@@ -1 +1 @@
-{"JARDIANCE": 8.244784523169459, "null": 1.1906014241440912}
\ No newline at end of file
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1.689229406737183, "RAPAMUNE": 2.281822116079012, "RASILEZ": 4.973419124597151, "REBETOL": 1.3725783635570863, "REGORAFENIB": 2.3459568544028206, "RELVAR": 0.744473406703703, "REMICADE": 0.4918710045399659, "REVATIO": 2.096548311481248, "REVLIMID": 1.508551028568588, "RIBAVIRIN": 0.5413548687619633, "RIBOCICLIB": 0.5527013488580232, "RINVOQ": 0.9799551027554032, "RITUXIMAB": 0.6344348328674897, "RIVAROXABAN": 3.707035108207879, "ROACTEMRA": 1.9622599946229964, "ROTATEQ": 0.4072130760373674, "RUBRACA": 0.510338536659462, "RUXOLITINIB": 0.8155719531152897, "SAMSCA": 3.2546033438959947, "SAXENDA": 0.3105088815990167, "SHINGRIX": 0.3588853249277534, "SIFROL": 5.378614452202058, "SILDENAFIL": 2.1343916733515877, "SIMPONI": 0.7172128602853047, "SKYRIZI": 0.7547053467173358, "SOLIRIS": 1.2900985302790584, "SOVALDI": 2.31561556491414, "SPIKEVAX": 0.3919862541404971, "SPIRONOLACTONE": 3.8156087003344368, "SPRYCEL": 1.9574817878799848, "STALEVO": 0.4233511929985999, "STELARA": 0.614977216304114, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8393.json
index 8ddf635301d..629a0809ebc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8393.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8393.json
@@ -1 +1 @@
-{"null": 1.2676312009724853}
\ No newline at end of file
+{"null": 0.4538419556163846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8394.json
index 6cc86e63e10..d5c522bd13f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8394.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8394.json
@@ -1 +1 @@
-{"FORXIGA": 42.50346171480211, "JARDIANCE": 43.2396294930749, "MEPOLIZUMAB": 13.163009888939, "TIVICAY": 120.02154130022788}
\ No newline at end of file
+{"BUSULFAN": 24.91840306938933, "BYETTA": 11.54977510854166, "JANUVIA": 15.763101205581638, "NOXAFIL": 80.13697504153676, "SAXENDA": 15.68004635983038, "VICTOZA": 28.363010968782906, "null": 0.6045970542054858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8395.json
index d0f26df5def..86662688579 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8395.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8395.json
@@ -1 +1 @@
-{"JARDIANCE": 24.27721596019476, "null": 1.015699803528595}
\ No newline at end of file
+{"COMIRNATY": 0.2082951016219758, "null": 1.0325597620991414}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8396.json
index f5e16260c3d..f63be7b1214 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8396.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8396.json
@@ -1 +1 @@
-{"TOVIAZ": 35.666869643098714, "ZOSTAVAX": 11.866572033876968, "null": 1.4503228779015842}
\ No newline at end of file
+{"null": 0.5498282749676868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8397.json
index e5b694b03f5..47c7bf06b18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8397.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8397.json
@@ -1 +1 @@
-{"BRILIQUE": 13.228543319656064, "CLOPIDOGREL": 10.383615459219037, "ELIQUIS": 33.31290169044828, "LIXIANA": 44.1060183245777, "PLAVIX": 14.492368530081992, "SUTENT": 2.4395608394843777, "VOTRIENT": 4.879666110347417, "XTANDI": 6.414623725004774}
\ No newline at end of file
+{"HUMALOG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8398.json
index cd5708451e1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8398.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8398.json
@@ -1 +1 @@
-{"FORSTEO": 38.47208248559957}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8399.json
index d0712a08bd1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8399.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8399.json
@@ -1 +1 @@
-{"null": 1.8516550839198065}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/84.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/84.json
index 841ecd7fe16..02d0611f89a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/84.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/84.json
@@ -1 +1 @@
-{"COVID19": 4.546024796603692}
\ No newline at end of file
+{"CIMZIA": 10.63146616944403, "ENTYVIO": 34.765149356711426, "STELARA": 9.54941805447604, "null": 0.7660779806791062}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/840.json
index 1814f475b18..793d94556a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/840.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/840.json
@@ -1 +1 @@
-{"GARDASIL": 79.02833825866827}
\ No newline at end of file
+{"ARAVA": 13.803198171361196, "null": 0.7163965810284204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8400.json
index be6030deaf3..6484a6d4d01 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8400.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8400.json
@@ -1 +1 @@
-{"null": 2.1476805008371294}
\ No newline at end of file
+{"KALETRA": 33.00016053195305, "null": 1.9651547052237388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8401.json
index a4c0e0d9eac..57a24b12268 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8401.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8401.json
@@ -1 +1 @@
-{"null": 2.070447818919116}
\ No newline at end of file
+{"null": 0.5253215492245955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8402.json
index cc1b932b434..54e6411a20b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8402.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8402.json
@@ -1 +1 @@
-{"ABILIFY": 4.544969972524501, "BETMIGA": 17.972295595713625, "CYMBALTA": 5.018323696603995, "EMPAGLIFLOZIN": 21.18056836897433, "OLANZAPINE": 2.512166259223931, "SIFROL": 21.89736590855564, "TOVIAZ": 29.163745407333025, "ZYPREXA": 10.658317809607908, "null": 2.499815077900107}
\ No newline at end of file
+{"ABACAVIR": 9.745763986665612, "ALIMTA": 4.050268647332098, "AMINOSALICYLIC": 3.2860666445853672, "ASPARAGINASE": 31.79229053316334, "ATAZANAVIR": 10.043197559554718, "CELLCEPT": 2.2690072030481234, "CICLOSPORIN": 3.1986762344690023, "CIMZIA": 1.0301137797790196, "CLOPIDOGREL": 1.2332883477830665, "COSENTYX": 20.510984450543745, "DARUNAVIR": 19.64763115173859, "DELAMANID": 24.628368010155995, "ELIQUIS": 0.5310823231301264, "JORVEZA": 321.3204320895036, "KALETRA": 12.20647809567552, "PEGASYS": 0.5172049591649198, "PEGINTERFERON": 3.590199469276407, "RELVAR": 66.56762370251242, "RITUXIMAB": 4.126652145243305, "STELARA": 1.1231304047001371, "TACROLIMUS": 15.158382280624116, "TRELEGY": 7.979975030086464, "XALKORI": 6.359841939999329, "null": 1.221164929365255}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8403.json
index 39bce3c131f..86a79342e6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8403.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8403.json
@@ -1 +1 @@
-{"ABILIFY": 1.1165431840632476, "ACTOS": 2.7620160898155084, "ARIPIPRAZOLE": 2.020438328280321, "AUBAGIO": 4.48580835101655, "BETAFERON": 2.035830871649755, "BETMIGA": 13.598836000635425, "BIKTARVY": 1.3194355323468414, "BRINTELLIX": 1.3743222483941036, "BRIVIACT": 4.584272025615266, "BUPIVACAINE": 2.994754400430537, "BUPRENORPHINE": 1.7592532115207336, "COMTAN": 2.0885651192381705, "DELAMANID": 2.964045100296247, "DULOXETINE": 1.4511127581280885, "EMPAGLIFLOZIN": 1.9494917686780309, "ENTACAPONE": 4.874628567359238, "ESMYA": 12.266455029975042, "EXELON": 7.123450693544794, "EXFORGE": 1.177308506332517, "FAMPYRA": 4.406174247849132, "FESOTERODINE": 19.09595546932221, "FORSTEO": 5.962328050010876, "FORXIGA": 4.582217489823612, "GARDASIL": 2.2921957299204183, "IBUPROFEN": 1.1879589311509613, "IRBESARTAN": 6.378393739002189, "JARDIANCE": 3.713138474728701, "KEPPRA": 2.041263588073656, "KETOCONAZOLE": 9.487403754425392, "LATUDA": 2.102421555931233, "LEMTRADA": 1.3674679900487858, "LYRICA": 2.4252676051722104, "MEMANTINE": 8.13235659100843, "MENVEO": 1.7993120510409195, "MOVYMIA": 9.093557188303851, "NOT": 2.281109379589915, "OLANZAPINE": 2.2507077602968293, "OXYBUTYNIN": 7.888278650636662, "PANTOPRAZOLE": 3.3485943975497943, "PLEGRIDY": 1.2399406567282831, "PREGABALIN": 1.1538654240437882, "RISPERIDONE": 4.349393433948786, "SAXENDA": 1.0299860914692027, "SUFENTANIL": 2.5027041985782965, "SYCREST": 9.408509834622276, "TOVIAZ": 12.796172326019976, "VIMPAT": 1.194835094226577, "XTANDI": 2.1573132057832267, "ZOSTAVAX": 1.898006062717432, "ZYPADHERA": 2.6666043959039936, "ZYPREXA": 3.379143310864157, "null": 1.9626775724746293}
\ No newline at end of file
+{"CELLCEPT": 0.8675651955543691, "CICLOSPORIN": 0.5431039700439807, "CYTARABINE": 1.7947375368328766, "ELIQUIS": 0.4586029442365028, "ENVARSUS": 73.47984765264044, "GREPID": 63.390300370528976, "LANTUS": 0.5562494189053451, "PEGASYS": 0.2507557762757086, "STELARA": 0.6382552488253713, "TRELEGY": 1.4270589579176658, "XELJANZ": 0.3419497685837134, "XTANDI": 0.56706574926664, "null": 15.78506387299578}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8404.json
index ab3431e6430..393a4e4ad7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8404.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8404.json
@@ -1 +1 @@
-{"COMIRNATY": 1.629320295360161}
\ No newline at end of file
+{"LANTUS": 90.23988747741272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8405.json
index d787798e9b8..9dedd88faf9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8405.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8405.json
@@ -1 +1 @@
-{"CICLOSPORIN": 6.6964134246138, "CLOPIDOGREL": 9.7322779630798, "null": 1.383254093591616}
\ No newline at end of file
+{"null": 1.1178290214646136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8406.json
index 10594824a58..da0ab863192 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8406.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8406.json
@@ -1 +1 @@
-{"ABILIFY": 1.8231159079818764, "AERIUS": 1.3271072926614698, "ANORO": 6.201584568406242, "APROVEL": 1.4987914409651004, "ARIPIPRAZOLE": 1.002240690195135, "BETMIGA": 43.47283709846098, "BRINTELLIX": 2.5784244379528025, "BUPIVACAINE": 6.604343248881143, "BUPRENORPHINE": 1.192362783689099, "BUVIDAL": 6.081981140639653, "CABAZITAXEL": 3.253260962752495, "CELECOXIB": 3.729241956348934, "COAPROVEL": 1.1253964715574336, "COMTAN": 1.0675593233854557, "CYMBALTA": 2.358118189033612, "DULOXETINE": 2.0879347173852185, "EBIXA": 3.4123145560250343, "EMEND": 1.2860422667760738, "ENTACAPONE": 3.306935925816632, "ERLEADA": 1.5248784850144108, "FAMPYRA": 1.2938208730805554, "FENTANYL": 2.3402670069900107, "FORXIGA": 2.137579875037405, "FYCOMPA": 2.9912568767672965, "INCRUSE": 8.69593521411426, "INVEGA": 2.343642392080649, "JARDIANCE": 1.383287668679526, "KETOCONAZOLE": 4.849656710869163, "LATUDA": 3.586005534046205, "LEMTRADA": 1.2627571717122246, "LYRICA": 3.242682768891989, "MELATONIN": 1.8379537897644016, "MIRABEGRON": 24.650958829031502, "OLANZAPINE": 2.807135647745135, "ORENCIA": 2.2328524441611832, "OXYBUTYNIN": 22.1011199461109, "PREGABALIN": 1.4477198404200475, "PRITOR": 8.228538927804658, "QARZIBA": 7.054956469212461, "RANOLAZINE": 4.446116108841981, "RELVAR": 2.5977026904614884, "RISPERIDONE": 1.3836679275413255, "SILODOSIN": 10.201231061991292, "SPINRAZA": 1.8595017734224064, "SPIRONOLACTONE": 1.0341784645452552, "STALEVO": 1.2859950257181088, "SUFENTANIL": 1.0098138643878154, "SYCREST": 5.11871772005341, "TAMIFLU": 1.0282874808210023, "TOVIAZ": 300.15280838641866, "TRELEGY": 13.438931603965022, "VIAGRA": 2.471502722925835, "XOFIGO": 1.5306798032399114, "XTANDI": 1.2841957656108585, "ZYPADHERA": 1.27492654398601, "ZYPREXA": 2.6311103210662243, "null": 2.3085393354672585}
\ No newline at end of file
+{"COMIRNATY": 0.1833227462258639, "SPIKEVAX": 0.7845144204589702, "null": 2.836699505313412}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8407.json
index 31c24b1fb01..3eeada37bc5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8407.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8407.json
@@ -1 +1 @@
-{"ADENURIC": 206.91405336777973, "ALEMTUZUMAB": 188.00131186300544, "LEMTRADA": 56.50905027710078}
\ No newline at end of file
+{"BUDESONIDE": 2.9712665119686616, "CYMBALTA": 2.346536871950712, "ELIQUIS": 2.9268676739132755, "IBRANCE": 1.943854400481036, "KEYTRUDA": 1.68657783928477, "NUCALA": 8.337202242597664, "PEGASYS": 1.616117987192392, "PLAVIX": 2.7361597269126694, "SOMATROPIN": 49.96482074252936, "SUTENT": 1.1534761348104126, "TOZINAMERAN": 0.3280738499544628, "VIAGRA": 7.571547072739969, "null": 1.912988140990457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8408.json
index 8a596a1d209..69f96c00b82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8408.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8408.json
@@ -1 +1 @@
-{"null": 1.807890886590464}
\ No newline at end of file
+{"MEKINIST": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8409.json
index 8b8e1bb10ce..100f0a54d16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8409.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8409.json
@@ -1 +1 @@
-{"JARDIANCE": 53.39968978486581, "MIDAZOLAM": 108.9697483895517}
\ No newline at end of file
+{"XOLAIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/841.json
index bcb782c65b1..775b4dbece9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/841.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/841.json
@@ -1 +1 @@
-{"null": 6.106621335564846}
\ No newline at end of file
+{"COMIRNATY": 0.242243952297488, "ZOSTAVAX": 6.494443494710285, "null": 1.0390474992168746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8410.json
index bff454fdf6d..b781841f95a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8410.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8410.json
@@ -1 +1 @@
-{"JARDIANCE": 16.73473236229109}
\ No newline at end of file
+{"null": 1.4267490696532728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8411.json
index 84e6aaec948..bef73b93278 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8411.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8411.json
@@ -1 +1 @@
-{"ADALIMUMAB": 3.202560074789494, "BUDESONIDE": 1.7640378025650176, "BYETTA": 4.214876729977447, "ELIQUIS": 1.5122843871745624, "FAMPYRA": 6.585026351261908, "FORXIGA": 4.379137090374609, "GARDASIL": 1.3209831646442924, "HYDROCORTISONE": 26.60324510581443, "JARDIANCE": 1.808264982029543, "NUCALA": 4.849096109410918, "SUTENT": 2.013013165515432, "TECFIDERA": 83.19803877622537, "TOVIAZ": 13.922313747760397, "TRELEGY": 5.0122756464477325, "XELJANZ": 1.3437375425091762, "XTANDI": 2.7969391403258377, "ZOSTAVAX": 2.742348726621436, "null": 1.1065236435021937}
\ No newline at end of file
+{"APREPITANT": 221.55515272500247, "CLOPIDOGREL": 7.97843653009496, "ELIQUIS": 7.469432126664886, "NEXAVAR": 5.47133373356446, "PLAVIX": 19.129693117713806, "SUTENT": 3.692715503383607, "null": 0.8809596239218568}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8412.json
index 132285d68af..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8412.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8412.json
@@ -1 +1 @@
-{"ACTOS": 1.5106842269246017, "AERIUS": 1.5111681607802825, "AFINITOR": 1.1625373889556028, "ALEMTUZUMAB": 1.2768493410897062, "ALPELISIB": 1.8883075679141803, "ANTIBIOTICS": 4.69448113040033, "ATEZOLIZUMAB": 1.3561520958079294, "AUBAGIO": 4.492574394020573, "AVASTIN": 1.1741917686603476, "AVONEX": 2.528806725828647, "AZACITIDINE": 1.0780779575785764, "AZATHIOPRINE": 1.2273284870259396, "BASILIXIMAB": 3.103544779536041, "BELATACEPT": 16.386387938060963, "BELIMUMAB": 2.1392731127664946, "BENLYSTA": 4.5750034085677305, "BETAFERON": 1.3470391054461737, "BETMIGA": 6.375076444038133, "BEVACIZUMAB": 1.159093316062688, "BOCEPREVIR": 2.0798926087033154, "BORTEZOMIB": 1.5670907474974087, "BRAFTOVI": 1.9084655780654416, "BUMETANIDE": 1.4544837421865582, "BYDUREON": 1.323955065966219, "BYETTA": 1.1776214368371252, "CABOMETYX": 1.24557819277914, "CAPECITABINE": 1.023461933757172, "CAPRELSA": 1.6903712220214957, "CELLCEPT": 4.037406104940371, "CIMZIA": 2.708509494914809, "CINACALCET": 2.260921714591871, "CINRYZE": 1.338510088306936, "CIRCADIN": 1.0108945501794786, "COAPROVEL": 1.1321506660797296, "COSENTYX": 1.7039194104665725, "DAPAGLIFLOZIN": 2.3658192235690345, "DARATUMUMAB": 3.5546271390207265, "DARZALEX": 1.1203067207236137, "DASATINIB": 3.019415064519037, "DOXORUBICIN": 1.0237687097348205, "DULAGLUTIDE": 1.1841166022577998, "DULOXETINE": 1.2601684681015903, "EBIXA": 1.3986742374037833, "ELIQUIS": 1.7771561888800893, "EMPAGLIFLOZIN": 8.772579285498262, "ENALAPRIL": 5.65841191026963, "ENBREL": 1.134675804009448, "ENTYVIO": 2.166459099896034, "ENZALUTAMIDE": 1.3819965021487637, "EPADERM": 22.01120359325052, "EPOETIN": 1.520583597098055, "ERLEADA": 1.068757838723805, "ESBRIET": 2.6492060212044946, "ESOMEPRAZOLE": 1.2800283546127995, "ETANERCEPT": 2.926756893845459, "EVEROLIMUS": 1.0697232719483212, "EVRA": 1.6297723641118125, "EXELON": 3.859158954182993, "EXFORGE": 1.41870815203562, "EXJADE": 2.1815568398810745, "EXVIERA": 1.6690154794486969, "FAMPRIDINE": 3.3210228222224587, "FAMPYRA": 8.871595510774332, "FASLODEX": 1.1897837162991327, "FIRDAPSE": 3.2972756571537345, "FORSTEO": 1.3830862239174813, "FORXIGA": 24.06163086509158, "FOTIVDA": 3.483635647762165, "GALAFOLD": 1.4511583910981372, "GALVUS": 1.4233140225976249, "GILENYA": 3.4796650318437736, "GLIBENCLAMIDE": 1.7377896841494913, "HALAVEN": 1.09225771499811, "HIZENTRA": 3.164035086404197, "HUMALOG": 1.8209183366068995, "HUMIRA": 1.985216333399056, "HYDROCHLOROTHIAZIDE": 2.2699568972014603, "HYDROCORTISONE": 1.369561112005664, "HYQVIA": 3.359981089821016, "IBRANCE": 3.3060110375070635, "IMBRUVICA": 3.0431267281356065, "INCIVO": 2.421747718299109, "INCRUSE": 1.9878277534241853, "INDINAVIR": 2.3910834119170024, "INLYTA": 1.2784131660083795, "INVOKANA": 8.990498459148343, "JAKAVI": 2.256711457619597, "JANUMET": 1.6596597219777036, "JANUVIA": 1.5628633061039423, "JARDIANCE": 22.634416998893684, "JEVTANA": 1.8332285836733733, "KEPPRA": 1.2808183052564903, "KESIMPTA": 3.3011410479889527, 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\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8413.json
index 8ca364ee730..961e09dafd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8413.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8413.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 15.84611562356006, "CELLCEPT": 6.215936288411734, "CICLOSPORIN": 4.393551872612246, "CYMBALTA": 5.474852993934862, "FORXIGA": 13.725104036814848, "JARDIANCE": 7.238293910795768, "METHOTREXATE": 5.647778706045294, "MIRABEGRON": 113.56636034178511, "NOT": 22.279676895935197, "OCEAN": 694.9936888732852, "SIMPONI": 3.542583019937372, "XELJANZ": 5.656062041954677}
\ No newline at end of file
+{"null": 1.141705649344067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8414.json
index cfc50e765bb..eebc4158426 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8414.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8414.json
@@ -1 +1 @@
-{"FORXIGA": 86.12694751725085, "JARDIANCE": 48.17769250858611}
\ No newline at end of file
+{"null": 1.0444875074945448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8415.json
index 4b1a9e25fa8..dbe024f862b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8415.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8415.json
@@ -1 +1 @@
-{"METHOTREXATE": 33.68296456542038}
\ No newline at end of file
+{"null": 2.829369566940733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8416.json
index 4dca228d7b4..575d5059550 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8416.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8416.json
@@ -1 +1 @@
-{"CELLCEPT": 75.76259888905591}
\ No newline at end of file
+{"CLOPIDOGREL": 64.63716601844064, "null": 1.5687787135911493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8417.json
index cea4aca9f01..3df55bf7482 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8417.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8417.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1607934075392468, "EFAVIRENZ": 86.96421101221651, "JARDIANCE": 12.089913089006986}
\ No newline at end of file
+{"null": 3.993136318173274}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8418.json
index ffb67fcdeb4..2c8bd31f521 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8418.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8418.json
@@ -1 +1 @@
-{"null": 2.831712131471681}
\ No newline at end of file
+{"null": 0.8894125681891993}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8419.json
index 85731f637ec..9fbbc8f4b40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8419.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8419.json
@@ -1 +1 @@
-{"BUSULFAN": 15.6178632561089, "CICLOSPORIN": 2.709496112152312, "FAMPYRA": 31.152876266958145, "JARDIANCE": 4.068522557079353, "KALETRA": 8.909395589077814, "KEYTRUDA": 1.53905144923588, "SUTENT": 1.455178298770235, "TOVIAZ": 24.78550128291997, "XTANDI": 5.677076881147115, "null": 1.1787859218928425}
\ No newline at end of file
+{"null": 1.7094405736763596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/842.json
index 27ea520c38e..b8d844f4366 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/842.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/842.json
@@ -1 +1 @@
-{"ABATACEPT": 5.950654589065102, "ADALIMUMAB": 6.918442928061056, "ANAKINRA": 3.061743127016584, "APREMILAST": 21.484128842708625, "ARANESP": 1.3964987422572626, "ARAVA": 2.1385786500683297, "AUBAGIO": 1.679042304287922, "AZATHIOPRINE": 5.791842799890136, "BUSULFAN": 1.7753480752806303, "BYDUREON": 2.477330726259868, "BYETTA": 1.4977253390179546, "CELLCEPT": 9.791812639669704, "CIALIS": 130.69036397828594, "CICLOSPORIN": 9.920464538804046, "CIMZIA": 2.1734574986539923, "COAPROVEL": 3.7162404085982494, "COSENTYX": 2.1524853534585784, "DEXAMETHASONE": 1.769063767233949, "ELIQUIS": 1.0282581249045293, "ENBREL": 19.814006380777894, "ENTYVIO": 1.7068063418198682, "FORSTEO": 1.2148576252897432, "HUMIRA": 2.140917785821056, "IMBRUVICA": 11.642699131359116, "JAKAVI": 14.183000514784224, "MEKINIST": 1.141887893805524, "MEPOLIZUMAB": 1.9802701354166852, "METHOTREXATE": 1.184575414308978, "MYCOPHENOLATE": 3.82562973979104, "OPTIMARK": 1.521402316594742, "REMICADE": 3.964363311934308, "REVLIMID": 9.633420880079411, "RINVOQ": 3.5212538288788267, "RITUXIMAB": 2.7824853779707857, "ROACTEMRA": 6.237390607335793, "RUXOLITINIB": 15.14115750571396, "SIMPONI": 3.695839058412672, "STELARA": 8.330572904961754, "TADALAFIL": 45.30284295792817, "TREMFYA": 2.1642882776144337, "VFEND": 1.334066109705635, "VIAGRA": 2.3212879676148157, "XELJANZ": 3.3918565608485305, "ZELBORAF": 9.46161612810584, "ZOSTAVAX": 2.8018369152416187}
\ No newline at end of file
+{"ELIQUIS": 9.675158963182872, "ZOSTAVAX": 10.557504203278867, "null": 1.4394564812295323}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8420.json
index b9cba3ca8f0..36fc81b0461 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8420.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8420.json
@@ -1 +1 @@
-{"COVID19": 1.167283840035968, "null": 1.145336733669354}
\ No newline at end of file
+{"APREPITANT": 3985.207007354716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8421.json
index 59917020cd6..9a9f47e4dae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8421.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8421.json
@@ -1 +1 @@
-{"ABACAVIR": 2.0456032338440244, "ALEMTUZUMAB": 25.74766403219155, "BELIMUMAB": 185.6437364662365, "BENLYSTA": 7.167127960484031, "BRILIQUE": 7.024387476827147, "CIMZIA": 1.0843116500628085, "FORSTEO": 4.530873981586754, "FORXIGA": 7.188746573197485, "IRBESARTAN": 47.405342593667335, "JARDIANCE": 4.753768613097327, "LYRICA": 3.162055417140008, "MEPOLIZUMAB": 3.943569849298, "TOVIAZ": 7.234271439301564, "null": 1.1425721754085465}
\ No newline at end of file
+{"null": 2.0439365941747494}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8422.json
index 2164c3fe5a3..29c3f98f4fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8422.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8422.json
@@ -1 +1 @@
-{"null": 2.6961666124093897}
\ No newline at end of file
+{"null": 2.096144235915871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8423.json
index 88cbf4a7fda..de7cf18c0cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8423.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8423.json
@@ -1 +1 @@
-{"SPIKEVAX": 21.33904342330189}
\ No newline at end of file
+{"null": 1.09168592872367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8424.json
index 621ca74f42c..f3894a26b3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8424.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8424.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 10.254663385925566, "CHAMPIX": 1.8507113551139005, "EXJADE": 3.849751641714897, "FENTANYL": 4.885538665302246, "FORXIGA": 13.100425612770389, "JARDIANCE": 1.8774613997354697, "SUTENT": 1.0099109609893198, "null": 1.6261545157146573}
\ No newline at end of file
+{"CHAMPIX": 1.3793215020567944, "CLOPIDOGREL": 6.786857665084271, "COMIRNATY": 0.2152846403593883, "IBRANCE": 2.129525949807175, "INLYTA": 4.114298365017184, "PLAVIX": 1.0004162084521633, "SPIKEVAX": 0.2922150261549072, "SUTENT": 0.7224023861436693, "TOZINAMERAN": 0.333050363064224, "VAXZEVRIA": 0.1951329995748367, "XALKORI": 8.37860289029666, "XELJANZ": 1.0396807497799736, "XTANDI": 1.7442749134807491, "null": 3.5260621865816413}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8425.json
index e0373665a88..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8425.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8425.json
@@ -1 +1 @@
-{"SPIKEVAX": 9.96885882609656}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8426.json
index 3db575e907b..c255903235f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8426.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8426.json
@@ -1 +1 @@
-{"null": 2.1447791014765603}
\ No newline at end of file
+{"DULOXETINE": 69.58921474775084, "ENVARSUS": 1472.667815408806, "KEYTRUDA": 6.376508759587331, "null": 0.8745332853885032}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8427.json
index 00b903af8bf..b9274eba4e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8427.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8427.json
@@ -1 +1 @@
-{"null": 3.601654780680706}
\ No newline at end of file
+{"MEPOLIZUMAB": 131.54390962365645, "null": 0.786278628214984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8428.json
index 1f68f7e6b4d..ca74e8c1b62 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8428.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8428.json
@@ -1 +1 @@
-{"FORSTEO": 157.2870200041915, "HEPSERA": 170.04222116763145}
\ No newline at end of file
+{"null": 1.7040195496537216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8429.json
index 886199c8d75..931bb63534d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8429.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8429.json
@@ -1 +1 @@
-{"null": 1.9021034470265756}
\ No newline at end of file
+{"CLOPIDOGREL": 20.297622648144188, "COMIRNATY": 0.2769780841818465, "CYMBALTA": 2.847355689287922, "SPIKEVAX": 0.3142475653650424, "VAXZEVRIA": 0.1628086107961068, "XOLAIR": 5.055931464545518, "null": 1.9774302024561377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/843.json
index 34ce69c36cd..4201022f82a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/843.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/843.json
@@ -1 +1 @@
-{"BRILIQUE": 17.689941080916757, "CLOPIDOGREL": 7.166514415946006, "ELIQUIS": 41.59817321592445, "LIXIANA": 30.532326583342925, "NEXAVAR": 5.584904634608644}
\ No newline at end of file
+{"AVASTIN": 7.323431601678797, "BRILIQUE": 5.59250241324721, "CABOMETYX": 5.651180133242971, "COMIRNATY": 0.9306762300846592, "ELIQUIS": 2.773339246012965, "EVENITY": 43.391853880427526, "KEYTRUDA": 1.3982918338804284, "LENVIMA": 20.651641066753616, "NEXAVAR": 4.539225268954751, "ROACTEMRA": 12.179535981589588, "SPIKEVAX": 0.5865033221830092, "STELARA": 2.7141646347987707, "SUTENT": 3.9955341771317134, "VAXZEVRIA": 0.2333972731927773, "XTANDI": 2.5107483294547484, "null": 0.7257123675542076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8430.json
index 139a8a9b8e2..d22ea2347d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8430.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8430.json
@@ -1 +1 @@
-{"null": 3.487298748185552}
\ No newline at end of file
+{"JAKAVI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8431.json
index 45281fb695b..731a739207a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8431.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8431.json
@@ -1 +1 @@
-{"BETMIGA": 24.517146887549977, "TOVIAZ": 61.63556198322418, "TRELEGY": 12.112919602068256, "null": 2.85677048486426}
\ No newline at end of file
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8432.json
index 072ddde1bf2..b8b08430624 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8432.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8432.json
@@ -1 +1 @@
-{"JARDIANCE": 132.541890987336}
\ No newline at end of file
+{"COSENTYX": 3.1708874006461256, "DEXAMETHASONE": 4.436586821145431, "IBRANCE": 2.423191209987982, "KEYTRUDA": 3.139014918535141, "null": 1.7519020754693009}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8433.json
index a21f10e1be6..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8433.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8433.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 19.65047433777163, "APIDRA": 14.101791098860597, "FORXIGA": 60.20756411542976, "HUMALOG": 10.572806907627688, "INSULIN": 8.979123534650236, "JARDIANCE": 48.30644250438396, "LANTUS": 7.59532391588997, "NOVORAPID": 32.5216082534543}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8434.json
index 30434473c5c..c487e0f4468 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8434.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8434.json
@@ -1 +1 @@
-{"ARANESP": 3.186975124658649, "AUBAGIO": 1.882559835468804, "BETMIGA": 12.27151118323859, "CHAMPIX": 1.1245804838333897, "CYMBALTA": 1.0631487041071632, "DULOXETINE": 14.264191576187356, "FASLODEX": 9.4735527255027, "FORSTEO": 2.8350637743882787, "FORXIGA": 10.759014790669577, "IBRANCE": 1.8004692565120863, "JARDIANCE": 10.206520759744848, "LANTUS": 1.2816570833817418, "PEGASYS": 1.1766827035077256, "SIMPONI": 1.6979381235834217, "SUTENT": 1.024217223132017, "TAMIFLU": 25.035341587166027, "XELJANZ": 1.7956881095999002, "null": 1.3792463428131003}
\ No newline at end of file
+{"BONVIVA": 13.964751634701608, "CELLCEPT": 3.86967295250991, "CICLOSPORIN": 1.4586926664271262, "CLOPIDOGREL": 4.114361241667411, "COMBIVIR": 6.6332895650558505, "COSENTYX": 2.4043139522057597, "ELIQUIS": 0.8417748487587257, "ENBREL": 2.2600910718574974, "KEYTRUDA": 1.3081946005102372, "NEXAVAR": 3.5069615807318923, "PLAVIX": 7.308732471703312, "SUTENT": 4.264049856619808, "XALKORI": 39.54303907059105, "null": 1.875802843162756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8435.json
index b61e71300e6..23f669a8bf1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8435.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8435.json
@@ -1 +1 @@
-{"null": 6.360958639031157}
\ No newline at end of file
+{"ELIQUIS": 5.315346055370577, "PLAVIX": 19.721068503451477, "null": 1.276007378654231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8436.json
index cc0620ef44a..15f3af9adc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8436.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8436.json
@@ -1 +1 @@
-{"null": 3.0570289746099717}
\ No newline at end of file
+{"ATAZANAVIR": 9.79834601501519, "AVASTIN": 7.711364584317572, "DAKLINZA": 31.465047549163856, "ELIQUIS": 1.4111124508201358, "EPCLUSA": 32.49532311478416, "EXVIERA": 23.090356520143576, "HARVONI": 39.19669618351153, "JAKAVI": 14.849565829668188, "LENVIMA": 45.64002112013237, "NEXAVAR": 64.93929950231525, "OCALIVA": 39.952015691301774, "PEGASYS": 7.543699955078122, "PEGINTRON": 3.1623683826218723, "PLAVIX": 1.923003420605677, "REBETOL": 25.72096970609256, "RIBAVIRIN": 26.03871474924258, "SOVALDI": 38.12947358924573, "null": 0.4102182298891726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8437.json
index 93abd02f54d..dcc06f924a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8437.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8437.json
@@ -1 +1 @@
-{"COVID19": 12.697824195159772}
\ No newline at end of file
+{"AFINITOR": 0.786851375764287, "ALIMTA": 4.193420773445412, "ARANESP": 0.9333143135555144, "ARAVA": 0.4912731564999799, "AVASTIN": 1.9802933271919676, "BEVACIZUMAB": 4.106193213454879, "BONVIVA": 20.14578747238701, "BRILIQUE": 1.8178573713936368, "BUDESONIDE": 0.7141430689784223, "BUPRENORPHINE": 3.5535131139853817, "BUSULFAN": 1.933186411259488, "BYETTA": 1.3754602665129148, "CAPECITABINE": 2.9325609371872137, "CELLCEPT": 2.479318067734293, "CHAMPIX": 1.7594502747128529, "CICLOSPORIN": 0.5667724502133051, "CLOPIDOGREL": 2.675873653081132, "COMIRNATY": 0.1298085770255303, "COSENTYX": 1.2200584550914306, "CYMBALTA": 0.6861446468773627, "CYTARABINE": 1.9700434954044832, "DABRAFENIB": 10.19261524565018, "DACLATASVIR": 14.351529796099808, "DOCETAXEL": 3.05545288688317, "ELIQUIS": 1.2959215168144955, "ENBREL": 0.9548373014339936, "ESOMEPRAZOLE": 5.102094065738626, "EXJADE": 1.972832080760374, "FORSTEO": 1.0822446409939288, "IBRANCE": 1.3646698545343037, "IBUPROFEN": 2.7151886728225905, "JANUMET": 1.989112958135192, "JANUVIA": 1.028970180324619, "JARDIANCE": 0.516076985348913, "KEYTRUDA": 1.7419750578245077, "LEVETIRACETAM": 0.9844869194397342, "OPDIVO": 2.219618530629032, "PANTOPRAZOLE": 2.9705615609590112, "PEGASYS": 1.0245343178120454, "PEGINTRON": 0.6755949735961767, "PLAVIX": 3.257751035367675, "PRADAXA": 16.670901475394526, "SAXENDA": 1.6725401402673117, "SPIKEVAX": 0.0865059021801506, "SPRYCEL": 1.7365166406015795, "SUTENT": 2.1063157799817405, "VAXZEVRIA": 0.0811981077807612, "VOTRIENT": 1.1955430989400873, "XALKORI": 16.014376240973323, "XELJANZ": 0.591666951156807, "XOLAIR": 0.7005755414583519, "ZOSTAVAX": 0.8369817674982482, "null": 1.8048225300711285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8438.json
index a931cc2f4be..a1a2f4afc97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8438.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8438.json
@@ -1 +1 @@
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\ No newline at end of file
+{"null": 4.169023149798513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8439.json
index c7e3dd1142f..030036d0bac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8439.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8439.json
@@ -1 +1 @@
-{"CHAMPIX": 2.427848163239457, "ENTRESTO": 4.504381016562586, "FORSTEO": 4.081167707268572, "FORXIGA": 13.545877315322372, "JARDIANCE": 25.12187277753988, "KEPPRA": 2.7640426517708674, "null": 1.767392878498243}
\ No newline at end of file
+{"null": 0.3676116530876853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/844.json
index 6deef33f9e1..5a76525025f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/844.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/844.json
@@ -1 +1 @@
-{"CANNABIDIOL": 1279.3293503412715}
\ No newline at end of file
+{"VAXZEVRIA": 6.964780810568316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8440.json
index 75f537243f4..84904f70c85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8440.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8440.json
@@ -1 +1 @@
-{"HEPSERA": 1118.0887978753017}
\ No newline at end of file
+{"PLAVIX": 16.35825849537442, "SUTENT": 3.763101482157203, "null": 1.3559745352563124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8441.json
index 1ffebc51a08..fd0151db097 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8441.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8441.json
@@ -1 +1 @@
-{"null": 1.359417735449565}
\ No newline at end of file
+{"PEMBROLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8442.json
index fab7d9555f1..8753f67a250 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8442.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8442.json
@@ -1 +1 @@
-{"null": 2.224121452268076}
\ No newline at end of file
+{"null": 0.7330776708644279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8443.json
index 6a2a1c84de1..0e7d8a4cb83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8443.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8443.json
@@ -1 +1 @@
-{"EXJADE": 17.29961655292397, "LUPKYNIS": 2514.128171906478}
\ No newline at end of file
+{"null": 0.6572227330518101}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8444.json
index a453dcbb011..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8444.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8444.json
@@ -1 +1 @@
-{"null": 1.9031182644603943}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8445.json
index a5a87282a10..b367b94ef2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8445.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8445.json
@@ -1 +1 @@
-{"null": 2.741472777367305}
\ No newline at end of file
+{"null": 0.475439175831845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8446.json
index a7abd625291..c950c15d3a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8446.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8446.json
@@ -1 +1 @@
-{"null": 2.774053073866298}
\ No newline at end of file
+{"RASILEZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8447.json
index 628c3bfffbd..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8447.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8447.json
@@ -1 +1 @@
-{"null": 1.6781571207598542}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8448.json
index 271de9f4d3d..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8448.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8448.json
@@ -1 +1 @@
-{"null": 1.607526672628602}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8449.json
index db1ef4236e4..04a76c22145 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8449.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8449.json
@@ -1 +1 @@
-{"JARDIANCE": 69.00186692361179}
\ No newline at end of file
+{"DOXORUBICIN": 464.68485732743153, "null": 1.7046627734140476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/845.json
index e4b2652f84c..6b1fdb12689 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/845.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/845.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"null": 1.402081161711441}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8450.json
index d9e1a507afa..7d83916b498 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8450.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8450.json
@@ -1 +1 @@
-{"KEYTRUDA": 37.388884063769616}
\ No newline at end of file
+{"FASLODEX": 47.44030446759679, "TESTOSTERONE": 181.24167592430973, "null": 4.372552515490089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8451.json
index e0227fc9e13..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8451.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8451.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 17.007714735917535, "ELIQUIS": 13.78863235625374}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8452.json
index 32d3f925a95..faa6172baa6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8452.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8452.json
@@ -1 +1 @@
-{"JARDIANCE": 72.46077711316912}
\ No newline at end of file
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8453.json
index 91e8f639fe3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8453.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8453.json
@@ -1 +1 @@
-{"JARDIANCE": 70.32229852377806}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8454.json
index b825228ce06..ac479390c79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8454.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8454.json
@@ -1 +1 @@
-{"AFINITOR": 3.124500738931743, "AZATHIOPRINE": 3.162755231820702, "CELLCEPT": 4.798199892531818, "CICLOSPORIN": 1.486256522723662, "ELIQUIS": 1.0075372358190298, "EMPAGLIFLOZIN": 24.96609213199823, "EVEROLIMUS": 10.178391297599736, "FAMPYRA": 4.778086687125195, "FORXIGA": 34.39395866274349, "HUMALOG": 1.3851073990609852, "INCIVO": 5.3671494703549625, "INVOKANA": 53.23538028705553, "JAKAVI": 1.7034478428123565, "JARDIANCE": 55.65477883895014, "MYCOPHENOLATE": 3.926918980393963, "NEXAVAR": 1.1508782509114102, "OPSUMIT": 1.3961809976527984, "OXYBUTYNIN": 10.918789326749826, "PEGASYS": 2.496483875191424, "PEGINTERFERON": 2.5348248441830563, "PLEGRIDY": 3.761959657749801, "RITUXIMAB": 1.5462008985938225, "ROACTEMRA": 3.1017044890155963, "SIMPONI": 1.8932960164956076, "SOLIRIS": 2.560234902103685, "STELARA": 1.6203923659107864, "XELJANZ": 1.6483512576101542, "XTANDI": 1.7074497464101062}
\ No newline at end of file
+{"null": 2.746865556057812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8455.json
index b28c122c63e..5964ec2bdf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8455.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8455.json
@@ -1 +1 @@
-{"ADENURIC": 1.3417985759745814, "AERIUS": 2.022772139277583, "ANTIHYPERTENSIVES": 3.0349387013136786, "ARZERRA": 2.239608770618571, "BENRALIZUMAB": 1.0327406619460582, "BETMIGA": 1.4655697774220346, "BEXSERO": 2.8493186136188005, "BINOCRIT": 1.7378816255457683, "BRIDION": 3.9003159958816656, "BUDESONIDE": 1.08261555157265, "CANCIDAS": 1.0978824263437597, "CELSENTRI": 1.2090444984154711, "CETUXIMAB": 1.3767052707467726, "CIMZIA": 1.121961948666583, "CLOPIDOGREL": 1.11672332389484, "COMIRNATY": 1.027715154650782, "DESLORATADINE": 3.219599444249587, "DUKORAL": 3.872641258125325, "ENTYVIO": 1.0193263494137546, "EUCREAS": 1.2702613817957595, "FASENRA": 2.979043332122493, "FENTANYL": 1.007510573882388, "FLEBOGAMMA": 2.232238117157256, "FLUCELVAX": 2.456011636788069, "GALVUS": 1.5298361937055132, "GARDASIL": 1.347029061494091, "GREPID": 3.42870808107878, "HEXYON": 4.1897069741485575, "HIZENTRA": 1.3018874119551915, "HYDROCHLOROTHIAZIDE": 1.9476332932185791, "HYDROCORTISONE": 1.1884759817728208, "IBUPROFEN": 1.1758437835096447, "IDACIO": 1.661327828748729, "INFANRIX": 3.309462328152583, "INHIXA": 5.099943814448609, "INSUMAN": 1.3110884629466155, "KAFTRIO": 1.0051589898348363, "KIOVIG": 2.775070812125989, "LEMTRADA": 1.4640043407829708, "LEVOFLOXACIN": 1.91640499882529, "MAVENCLAD": 1.0453389515005571, "MENQUADFI": 3.650229929913085, "MENVEO": 2.128916200330295, "MICARDISPLUS": 1.4699724522446056, "MIDAZOLAM": 1.72752372153644, "MMRVAXPRO": 3.3343229671625427, "MULTITRACE4": 52.12986064766994, "NAGLAZYME": 1.6359549944948633, "NIMENRIX": 2.612616351792876, "NIVESTIM": 2.451921111089596, "NUCALA": 1.6183799625385085, "OLOPATADINE": 3.071350674460613, "OMALIZUMAB": 3.73499466183055, "ONCASPAR": 6.837331823009941, "OSELTAMIVIR": 1.0853028807449554, "PEGASPARGASE": 2.684207431501586, "PREVENAR": 2.1173654720942245, "PRIVIGEN": 2.7677502414577764, "PROPRANOLOL": 1.1477311750229076, "PROTELOS": 1.2753421111664467, "QARZIBA": 1.796849386904436, "RETACRIT": 2.8671174536854944, "RIXATHON": 5.034284140491563, "ROACTEMRA": 2.1563565363282, "SHINGRIX": 1.2418999000036834, "SILGARD": 1.992823277292455, "SKYRIZI": 1.1231141266247684, "SPIKEVAX": 1.1233088377176663, "SUFENTANIL": 4.307513226225706, "SYMTUZA": 1.2505665806530046, "SYNFLORIX": 1.3045337421101064, "TAMIFLU": 1.7690761721299222, "TOUJEO": 1.051412585102966, "TREMFYA": 1.2810582804669934, "TWINRIX": 2.0789633497459845, "UROREC": 2.0178088753692727, "VORTIOXETINE": 1.2391700553456144, "XOLAIR": 6.430045808586802, "ZARZIO": 2.557703287386692, "ZIAGEN": 1.137294577799896, "ZYLLT": 9.606667415344369, "null": 2.14855599175597}
\ No newline at end of file
+{"EVISTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8456.json
index 7f9d56d3b6d..b1e23c11d1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8456.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8456.json
@@ -1 +1 @@
-{"COMIRNATY": 1.674316484347875}
\ No newline at end of file
+{"IBRANCE": 13.603157350865322, "null": 4.828179364339004}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8457.json
index 27c75794198..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8457.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8457.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1566210109280424}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8458.json
index 99d5b07838e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8458.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8458.json
@@ -1 +1 @@
-{"COMIRNATY": 2.3892183203417794, "GARDASIL": 1.4187050566002306, "SPIKEVAX": 6.508354758827746, "TOZINAMERAN": 2.124771531808137, "XOLAIR": 3.624366755925291}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8459.json
index 76e62a5440c..8d9f4a0a4e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8459.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8459.json
@@ -1 +1 @@
-{"null": 2.3526150684378715}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/846.json
index 071a03e218a..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/846.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/846.json
@@ -1 +1 @@
-{"null": 2.0933226683496997}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8460.json
index af46f00e34c..91908d37535 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8460.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8460.json
@@ -1 +1 @@
-{"SPIKEVAX": 3.776076810247838}
\ No newline at end of file
+{"null": 5.872786249805782}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8461.json
index ba2613ad196..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8461.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8461.json
@@ -1 +1 @@
-{"null": 1.2229875075149683}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8462.json
index d9a3df7008f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8462.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8462.json
@@ -1 +1 @@
-{"COMIRNATY": 1.3846148744634112}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8463.json
index 6878e1f033d..d315290256d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8463.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8463.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1317139370746476}
\ No newline at end of file
+{"null": 1.5184256102081408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8464.json
index 7dee1fd5056..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8464.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8464.json
@@ -1 +1 @@
-{"null": 1.6962176648425369}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8465.json
index 55833021228..53a90150e33 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8465.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8465.json
@@ -1 +1 @@
-{"COSENTYX": 4.273948313706167, "OMALIZUMAB": 8.947273126012538, "SIMPONI": 4.790339986845033, "TOZINAMERAN": 1.2488314716194524, "XOLAIR": 13.52977861737449}
\ No newline at end of file
+{"FORXIGA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8466.json
index 77aff780e94..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8466.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8466.json
@@ -1 +1 @@
-{"BUDESONIDE": 15.940698694820531, "NUCALA": 38.43816974395397, "SYNAGIS": 85.76848509527693, "TOZINAMERAN": 1.2952293561395336, "null": 1.272113570744745}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8467.json
index 4cd6b598305..b4f7877862b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8467.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8467.json
@@ -1 +1 @@
-{"null": 2.790604720356131}
\ No newline at end of file
+{"BUDESONIDE": 13.780891405367475, "COMIRNATY": 1.4760125509456508, "IBUPROFEN": 45.2498501146721, "SPIKEVAX": 0.8033254618825566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8468.json
index a48592528b8..d520537ede8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8468.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8468.json
@@ -1 +1 @@
-{"BYDUREON": 3.748669625840797, "CELLCEPT": 3.166509764761328, "EVISTA": 20.495797464059677, "FASLODEX": 2.462793266721403, "LANTUS": 1.7978506059378534, "OMALIZUMAB": 4.719952741127392, "SIMPONI": 3.0253010516988272, "STELARA": 3.277359316820671, "TRELEGY": 3.3438686214612376, "TREMFYA": 6.1678790483861725, "XELJANZ": 1.393765513977788, "XOLAIR": 1.7608612876857372, "null": 4.87186599063252}
\ No newline at end of file
+{"COMIRNATY": 0.3008826305202797, "MMRVAXPRO": 70.21447117876387, "null": 1.536237219415089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8469.json
index b6dcdfdfc95..757a2d68057 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8469.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8469.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4315995765998666, "null": 1.2875976150277055}
\ No newline at end of file
+{"CICLOSPORIN": 1.3426141045292168, "CIMZIA": 1.4587412545337335, "COMBIVIR": 10.299848992273906, "COMIRNATY": 0.0357789507849832, "DEXAMETHASONE": 3.095745275181816, "EXFORGE": 4.095754414978354, "FENTANYL": 3.812982960896264, "HERCEPTIN": 7.314465437185395, "SUBOXONE": 6.366040991467552, "TELMISARTAN": 27.02468754792876, "ZYPREXA": 1.3675836922519888, "null": 4.316266217238357}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/847.json
index 1c93f3be85b..69b5cb35248 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/847.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/847.json
@@ -1 +1 @@
-{"null": 2.5044046076704296}
\ No newline at end of file
+{"null": 0.7936388622360223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8470.json
index 870a71c12ca..56a780d62b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8470.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8470.json
@@ -1 +1 @@
-{"COMIRNATY": 1.547645096443063, "TOZINAMERAN": 1.0872049262260657, "null": 1.5867993408289456}
\ No newline at end of file
+{"AIMOVIG": 0.5583996032065742, "COMIRNATY": 17.02359594623523, "GARDASIL": 0.1989131826376173, "MODERNA": 7.137204516220444, "SPIKEVAX": 2.5391486020275877, "TOZINAMERAN": 0.8784870758405379, "VAXZEVRIA": 0.4571761557305241, "null": 0.0415883670246679}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8471.json
index c4b8078678d..8b900491e10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8471.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8471.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1208608818904446}
\ No newline at end of file
+{"null": 6.417134190607331}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8472.json
index 2e3cbbfa923..6c3f8a79977 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8472.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8472.json
@@ -1 +1 @@
-{"null": 7.563127125586946}
\ No newline at end of file
+{"ABACAVIR": 0.6760957114245161, "ADEMPAS": 6.724281081010858, "AMIKACIN": 4.12182206682986, "AZILECT": 13.40145811821922, "CELECOXIB": 3.5625772667323896, "CELLCEPT": 2.085882936533568, "CICLOSPORIN": 5.659228497887588, "CLOPIDOGREL": 1.0713437226302456, "COAPROVEL": 4.895831803362894, "COMIRNATY": 0.0782214817124004, "CYTARABINE": 0.958947464381748, "DAPTOMYCIN": 16.858437902920198, "DEXAMETHASONE": 2.0147123499887494, "ENOXAPARIN": 4.933717572946102, "ENTRESTO": 2.3769549331181525, "EXJADE": 1.2796102200909087, "GANCICLOVIR": 6.232025790696159, "IBUPROFEN": 3.410384022741265, "IRBESARTAN": 3.6716842470271143, "JARDIANCE": 0.5809001606809459, "KALETRA": 4.353578359069934, "KEPPRA": 0.5961919643641408, "KEYTRUDA": 0.4908657698269493, "KYMRIAH": 4.218055009751324, "LANTUS": 0.3308787296810989, "LEVETIRACETAM": 2.231500098946488, "LEVOFLOXACIN": 5.928091247710468, "LYRICA": 1.6834876376229262, "MIDAZOLAM": 3.167949903410463, "OLANZAPINE": 0.5368728758045361, "OPSUMIT": 1.2405591313777855, "OVITRELLE": 30.542230143812077, "RASILEZ": 6.340160121615348, "SOLIRIS": 2.399618766485799, "SPIKEVAX": 0.0503692432518305, "SPIRONOLACTONE": 5.317271328580789, "SUTENT": 0.4103902718265141, "TELMISARTAN": 5.370400027937494, "VAXZEVRIA": 0.085964267356932, "null": 3.028362415085179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8473.json
index 2facdc9444d..891f954a8d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8473.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8473.json
@@ -1 +1 @@
-{"CYMBALTA": 5.139953658140763, "ELIQUIS": 6.6627138568353725, "SUBOXONE": 16.9348419921784, "null": 1.5678199995000617}
\ No newline at end of file
+{"COMIRNATY": 2.094124968275052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8474.json
index d8272a1f269..9e753b04c39 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8474.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8474.json
@@ -1 +1 @@
-{"null": 1.4032656810513982}
\ No newline at end of file
+{"LYNPARZA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8475.json
index 6d07c5f9846..05f49f45089 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8475.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8475.json
@@ -1 +1 @@
-{"null": 1.5376831920133922}
\ No newline at end of file
+{"REMICADE": 242.94778403433585, "null": 0.803011352366573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8476.json
index ace7198cf19..34f6656ad12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8476.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8476.json
@@ -1 +1 @@
-{"ADEMPAS": 9.06019176767264, "CICATRIZANTS": 640.7550590872742, "COMIRNATY": 1.3454450386740489, "ELIQUIS": 2.8074527204748803, "ESMYA": 258.4913001725645, "FENTANYL": 1.166458678524101, "PLAVIX": 2.460827862492041, "RYEQO": 229.40645517067435, "TAMIFLU": 1.9976526762123283, "TOZINAMERAN": 1.1453145772164637, "XARELTO": 11.54904791316683, "null": 1.5406128425652044}
\ No newline at end of file
+{"AZILECT": 344.7596214391791, "CARBIDOPA": 532.4606717985048, "COMTAN": 114.64384055491416, "ENTACAPONE": 624.7224564583022, "LEVODOPA": 850.806344389586, "SIFROL": 71.00047408638419, "STALEVO": 227.7982496854132, "null": 0.6538635431696501}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8477.json
index 60347531184..1844c2365b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8477.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8477.json
@@ -1 +1 @@
-{"GONALF": 661.570138984048, "null": 11.009382794528372}
\ No newline at end of file
+{"AFINITOR": 21.265834739832467, "TASIGNA": 42.07626726820191, "XTANDI": 17.07118321948716, "null": 0.460069309967906}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8478.json
index 56dc349157b..76b36b3c558 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8478.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8478.json
@@ -1 +1 @@
-{"null": 3.635287123047323}
\ No newline at end of file
+{"SPIKEVAX": 0.5865874714166425, "SUTENT": 5.005842009498007, "VAXZEVRIA": 0.6691082137828263, "null": 0.2946558980285846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8479.json
index c2a5bce7c86..0c6861d5629 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8479.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8479.json
@@ -1 +1 @@
-{"BUPIVACAINE": 244.2284270762048, "FENTANYL": 21.04183814281389, "null": 1.7318402278723533}
\ No newline at end of file
+{"AFINITOR": 6.931107411245455, "AIMOVIG": 2.4749522289531725, "APIXABAN": 2.367367144679111, "AUBAGIO": 6.330094121484772, "CICLOSPORIN": 1.2243599825598706, "COMIRNATY": 0.1773463820550563, "DAPAGLIFLOZIN": 97.83932439009328, "ENBREL": 3.1008755414485925, "FASLODEX": 10.254229166778646, "FORSTEO": 2.9684354636912853, "HERCEPTIN": 9.586571978680464, "IBRANCE": 15.581446588262574, "IMBRUVICA": 46.01733734972725, "INSULIN": 3.876954683686501, "IRESSA": 7.312797983547702, "LONSURF": 13.521904378026498, "PEGASYS": 1.8697185730054016, "SPIKEVAX": 0.0893953726570972, "SUTENT": 2.276708699151885, "TAGRISSO": 37.42974064973691, "VAXZEVRIA": 0.0617887376640153, "XELJANZ": 1.3318209682812232, "null": 0.7546560666315882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/848.json
index 6b023145317..c258a99a042 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/848.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/848.json
@@ -1 +1 @@
-{"null": 1.009551223095855}
\ No newline at end of file
+{"ACLIDINIUM": 15.788116947577956, "ARANESP": 132.36880454306845, "AVANDAMET": 10.85419364374887, "AVANDIA": 17.233442658468967, "CLOPIDOGREL": 3.038304375366083, "COMIRNATY": 0.0684318461972381, "ELIQUIS": 3.0566469672531147, "ENTRESTO": 3.4958651742543574, "EXJADE": 3.64016087415864, "FORSTEO": 1.4956184485519306, "LANTUS": 0.6267110561904573, "MEPOLIZUMAB": 6.970835242640028, "OPSUMIT": 2.293622335142404, "SPIKEVAX": 0.121187608216481, "TASIGNA": 4.971231229658176, "TRACLEER": 6.174466580238899, "VAXZEVRIA": 0.0596864459789475, "ZOSTAVAX": 3.1366037193466263, "null": 1.012709560786008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8480.json
index 27b253a689d..d922da87b55 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8480.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8480.json
@@ -1 +1 @@
-{"COMIRNATY": 3.0441404208734646}
\ No newline at end of file
+{"ARAVA": 3.859445458869238, "COMIRNATY": 0.2315504927805158, "COSENTYX": 14.643002869057655, "DOCETAXEL": 18.733947733431304, "EVOLOCUMAB": 1639.7553507646785, "FASLODEX": 13.872443811895666, "SUTENT": 2.3181135166316458, "null": 0.6122931435032802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8481.json
index e4b2652f84c..ba9213c4c1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8481.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8481.json
@@ -1 +1 @@
-{"null": 1.3932360359023557}
\ No newline at end of file
+{"ABATACEPT": 29.40170431181298, "ADALIMUMAB": 35.375835258551376, "ARAVA": 1.0240211268888475, "AUBAGIO": 4.581009849075122, "CIMZIA": 7.6379571048673345, "COMIRNATY": 0.1043854482837653, "IBRANCE": 1.70756788534063, "KEYTRUDA": 1.053498638208021, "OPTIMARK": 3.5367906725961964, "PEGASYS": 0.7391220559610193, "null": 0.408807773951602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8482.json
index a0569d55624..951c93976b9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8482.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8482.json
@@ -1 +1 @@
-{"DOCETAXEL": 3.559454552087941, "ESMYA": 213.51712604834225, "EVISTA": 10.600438962067017, "IBRANCE": 1.0159704406283248, "JANUMET": 2.486831060181707, "JANUVIA": 2.2353113238085918, "RYEQO": 107.13312254126102, "SIMPONI": 4.046053176215624, "SOLIRIS": 2.7909059933957154, "STELARA": 1.452372945554821, "XELJANZ": 1.4581372566379496, "null": 1.672498088906997}
\ No newline at end of file
+{"ADALIMUMAB": 32.21729653862994, "ARAVA": 1.948844132375796, "CIMZIA": 12.498332587118398, "CLOPIDOGREL": 1.9789223295060452, "COMIRNATY": 0.0672447567517369, "COSENTYX": 2.262131560484994, "RITUXIMAB": 4.013578437512434, "SUTENT": 0.8262285836545454, "XELJANZ": 2.090315888198559, "ZOSTAVAX": 6.148040776945813, "ZYPREXA": 3.487010150680951, "null": 0.4278297865027016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8483.json
index 13552d775de..ea4026eb132 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8483.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8483.json
@@ -1 +1 @@
-{"ESMYA": 9645.11397923189}
\ No newline at end of file
+{"null": 2.996968933622857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8484.json
index d1f968e04f7..6f67beeb341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8484.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8484.json
@@ -1 +1 @@
-{"DOCETAXEL": 92.3979135954961, "VOTRIENT": 79.10750355765147}
\ No newline at end of file
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8485.json
index 5cd728aa338..f2d886f4698 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8485.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8485.json
@@ -1 +1 @@
-{"ESMYA": 5290.646315414552}
\ No newline at end of file
+{"IBRANCE": 16.825718348001885, "null": 1.1069231465729772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8486.json
index 49a0a5febe4..ca9c7da6954 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8486.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8486.json
@@ -1 +1 @@
-{"COMIRNATY": 8.087864480267562, "SPIKEVAX": 2.156346582957462}
\ No newline at end of file
+{"CYMBALTA": 4.378800262505348, "ZOSTAVAX": 18.17105037253078, "null": 1.9778524850354309}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8487.json
index 2a62a642c6d..e51b3f28478 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8487.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8487.json
@@ -1 +1 @@
-{"null": 3.859879244102083}
\ No newline at end of file
+{"null": 0.9390831921603298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8488.json
index cca51f8ef52..895aba44e78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8488.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8488.json
@@ -1 +1 @@
-{"ESMYA": 118.51616196599598, "EVISTA": 47.071154540269646, "HUMIRA": 9.233408654059543, "null": 1.4221726918912554}
\ No newline at end of file
+{"null": 1.1724972826029354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8489.json
index 9dd70054e53..234d8b85796 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8489.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8489.json
@@ -1 +1 @@
-{"FORSTEO": 14.07737883444102, "null": 1.1006265541438465}
\ No newline at end of file
+{"null": 0.6979324091643041}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/849.json
index e6b814faf61..bac674c2fa1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/849.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/849.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 87.24618100475831}
\ No newline at end of file
+{"null": 1.2435810430680123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8490.json
index 193abd76302..69f96c00b82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8490.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8490.json
@@ -1 +1 @@
-{"MISOPROSTOL": 1028.3502611416975, "null": 9.571607644547427}
\ No newline at end of file
+{"MEKINIST": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8491.json
index 4f0a8411129..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8491.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8491.json
@@ -1 +1 @@
-{"COMIRNATY": 4.570349250029271, "SPIKEVAX": 1.8352724449950115, "TOZINAMERAN": 1.9964460539054776}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8492.json
index 90754664d77..152122da506 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8492.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8492.json
@@ -1 +1 @@
-{"COMIRNATY": 2.968059819743332}
\ No newline at end of file
+{"COMIRNATY": 3.138729165028876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8493.json
index e53ee018243..891f954a8d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8493.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8493.json
@@ -1 +1 @@
-{"AVASTIN": 1.5720283179793826, "AZATHIOPRINE": 2.245735817656659, "BEOVU": 310.5659431194356, "BEVACIZUMAB": 1.5800544052080328, "BINIMETINIB": 25.963781361970856, "BRAFTOVI": 22.6732421501873, "BROLUCIZUMAB": 142.12030696636904, "CELLCEPT": 1.0463915167251858, "CICLOSPORIN": 1.9496119213167893, "CIDOFOVIR": 50.39468728080397, "CIMZIA": 8.993196914260153, "COBIMETINIB": 29.866612985821803, "COSENTYX": 10.97550471415921, "COTELLIC": 32.431906243672366, "DABRAFENIB": 35.17084728831189, "ENBREL": 1.7242731113056602, "ENTYVIO": 3.566458333413661, "EYLEA": 98.5074723354702, "HUMIRA": 5.890106344139372, "IPILIMUMAB": 10.417910022718075, "KEYTRUDA": 4.246183516964763, "MEKINIST": 28.61920950305159, "METHOTREXATE": 1.0252486158378231, "MYCOPHENOLATE": 5.969201817680083, "NEVANAC": 14.661846641593494, "NORVIR": 7.044802104637939, "OPDIVO": 7.802749831210593, "PEMBROLIZUMAB": 3.437673698302169, "ROACTEMRA": 1.5710593544951537, "SHINGRIX": 1.3609049094007886, "SIMPONI": 8.098305670883718, "STELARA": 1.8851716618254808, "TAFINLAR": 33.144610733618265, "VEMURAFENIB": 21.973604597435383, "YERVOY": 5.682803675190282, "ZELBORAF": 14.33562206950657, "ZOSTAVAX": 1.0172052836115948}
\ No newline at end of file
+{"COMIRNATY": 2.094124968275052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8494.json
index 01572d9cebb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8494.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8494.json
@@ -1 +1 @@
-{"null": 3.206012394354377}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8495.json
index e31ec4d77f9..9ec10b68b55 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8495.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8495.json
@@ -1 +1 @@
-{"COMIRNATY": 1.182651640574652}
\ No newline at end of file
+{"SHINGRIX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8496.json
index b26e5343234..2437166c54a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8496.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8496.json
@@ -1 +1 @@
-{"CICLOSPORIN": 2.0273823482730573, "DEXAMETHASONE": 5.794511894901075, "KEYTRUDA": 1.8379146003855789, "TOZINAMERAN": 1.610001627887692, "ZOSTAVAX": 4.506964963583756}
\ No newline at end of file
+{"COMIRNATY": 0.4677303920702239, "SHINGRIX": 24.1506742503519, "SPIKEVAX": 0.4326241638522302, "TOZINAMERAN": 1.9436473387442328, "ZOSTAVAX": 47.09749486020847, "null": 0.4208372224786438}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8497.json
index 2e74e4fe133..6ab3d20d0c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8497.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8497.json
@@ -1 +1 @@
-{"CIMZIA": 1.9659934080418515, "CYMBALTA": 1.0177509520412846, "GARDASIL": 13.765638125900646, "INFANRIX": 31.808213504448755, "MMRVAXPRO": 12.360323281803293, "PREVENAR": 59.395613897084125, "SPIKEVAX": 2.737371319048978, "TWINRIX": 99.80802683284112, "null": 1.306109475860988}
\ No newline at end of file
+{"COMIRNATY": 1.8348945557416407, "LYRICA": 1.6487500118029317, "METHOTREXATE": 1.012989948428212, "MODERNA": 1.0548673122156789, "NOT": 5.990997569429214, "RINVOQ": 9.633438659922293, "ROACTEMRA": 1.8738369448231424, "SHINGRIX": 40.91107645972315, "SIMPONI": 1.8488735193177903, "SPIKEVAX": 0.8307780982253745, "STELARA": 0.916691146242563, "TOZINAMERAN": 0.9834976229163442, "VAXZEVRIA": 0.3466228656356608, "XELJANZ": 4.478074845430009, "ZOSTAVAX": 102.69511806308526, "null": 0.3137947352089043}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8498.json
index c8facec5f68..d922259bb19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8498.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8498.json
@@ -1 +1 @@
-{"GARDASIL": 11.796504318858885, "MMRVAXPRO": 7.308917758624931, "ROTATEQ": 23.7675830682938, "TOZINAMERAN": 29.072777087524948, "VAXZEVRIA": 1.2640026697442293, "ZOSTAVAX": 11.508274203990172}
\ No newline at end of file
+{"COMIRNATY": 2.732624540464202, "SPIKEVAX": 0.9331657034657724, "TOZINAMERAN": 2.0592936833826263, "VAXZEVRIA": 1.151192405707844, "null": 0.5660545230954721}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8499.json
index 17b6c1d8687..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8499.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8499.json
@@ -1 +1 @@
-{"COMIRNATY": 10.741579880837469, "ECULIZUMAB": 1.2911582197969904, "MERCK": 3.301923646555068, "ROTARIX": 1.5530465705793173, "ROTATEQ": 4.128893392982556, "SHINGRIX": 7.83525686928528, "SILGARD": 1.5276103578829645, "SYNFLORIX": 1.662612088247819, "TOZINAMERAN": 1.5003968927941824, "VAXZEVRIA": 6.005217261560954, "ZOSTAVAX": 9.14507482156081}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/85.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/85.json
index 8114d7390fb..c68ef2e6d48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/85.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/85.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1390213519174974, "COVID19": 4.4596667087219055}
\ No newline at end of file
+{"null": 0.242302350377018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/850.json
index b4292a83807..b704bcb9133 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/850.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/850.json
@@ -1 +1 @@
-{"COMIRNATY": 2.831725534817686}
\ No newline at end of file
+{"CLOPIDOGREL": 6.208256403085688, "COMIRNATY": 0.4960401944375573, "ELIQUIS": 3.1014517685834297, "NOVOSEVEN": 74.40118164937415, "SPIKEVAX": 0.5118326481491566, "VAXZEVRIA": 1.4711742264057022, "null": 0.6244033924610065}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8500.json
index a6f92363b8e..7bfd5ecf8bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8500.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8500.json
@@ -1 +1 @@
-{"COMIRNATY": 1.68566540163334, "COVID19": 1.3183052032742917, "SPIKEVAX": 1.0186991390848847, "VAXZEVRIA": 1.7652821922468565}
\ No newline at end of file
+{"COMIRNATY": 2.0892450991612668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8501.json
index c94684a2af7..eef5a8e90a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8501.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8501.json
@@ -1 +1 @@
-{"COMIRNATY": 2.426729076150728, "SPIKEVAX": 3.402988927522148}
\ No newline at end of file
+{"COMIRNATY": 5.099166153145951, "CYMBALTA": 3.823907393678701, "ELIQUIS": 3.164483517883396, "SPIKEVAX": 1.2885035800902855, "VAXZEVRIA": 1.9848955102558568, "null": 0.1304579474201583}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8502.json
index a3fb6de33f4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8502.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8502.json
@@ -1 +1 @@
-{"COMIRNATY": 2.1804213082970065, "VAXZEVRIA": 9.097066043231184}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8503.json
index 0dc400fca71..215f9c4f4d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8503.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8503.json
@@ -1 +1 @@
-{"COMIRNATY": 3.302135301115764, "COVID19": 2.9013942815098024, "SPIKEVAX": 2.9132756661457933, "TOZINAMERAN": 6.428050111348359, "VAXZEVRIA": 3.5712418496683846}
\ No newline at end of file
+{"ABACAVIR": 5.394833940515004, "ABILIFY": 3.654096292351168, "ATAZANAVIR": 36.32107323568782, "BUPIVACAINE": 89.2766103320988, "CICLOSPORIN": 1.8565550049053805, "COMIRNATY": 0.5777842545722022, "CRIXIVAN": 21.53586652576077, "ENFUVIRTIDE": 288.0299812836236, "GARDASIL": 1.1130207167390105, "HUMIRA": 5.881218698112993, "KEYTRUDA": 2.556990051022161, "PEMBROLIZUMAB": 8.031566335549025, "SAQUINAVIR": 798.8004375898169, "SPIKEVAX": 0.6056828551617697, "TOZINAMERAN": 0.813885399083994, "VAXZEVRIA": 0.3289979528235313, "null": 1.0983758689109473}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8504.json
index 6635f06e711..87dfe9cdf4c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8504.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8504.json
@@ -1 +1 @@
-{"COVID19": 1.029453312899293, "GARDASIL": 10.109298148657416, "MENVEO": 149.46037768367236, "SPIKEVAX": 1.8471427462368304, "TOZINAMERAN": 7.717756207141136, "ZOSTAVAX": 8.733367800009974}
\ No newline at end of file
+{"FENTANYL": 158.9447238677995, "null": 2.3858316619213147}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8505.json
index 2510ba34ddc..a97050eaa0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8505.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8505.json
@@ -1 +1 @@
-{"COMIRNATY": 2.855865068510885, "COVID19": 1.8266389040895497, "SPIKEVAX": 1.6762534820023305}
\ No newline at end of file
+{"GARDASIL": 2.504018289459586, "HEXYON": 109.67758439435184, "MMRVAXPRO": 4.972029947016519, "NIMENRIX": 9.797976447567253, "OLANZAPINE": 4.452219264325884, "ZYPREXA": 4.568121020654727, "null": 5.526304087827999}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8506.json
index a6809c910af..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8506.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8506.json
@@ -1 +1 @@
-{"COMIRNATY": 1.7597809535765758, "SPIKEVAX": 2.478082636637355}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8507.json
index 290a1287585..d7782f23945 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8507.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8507.json
@@ -1 +1 @@
-{"COMIRNATY": 2.063812368345737, "SPIKEVAX": 2.847796623496854}
\ No newline at end of file
+{"ATAZANAVIR": 24.372926836917816, "BIKTARVY": 19.559388367292687, "CELLCEPT": 9.010407859936866, "CICLOSPORIN": 4.634057460775123, "MYCOPHENOLATE": 31.335685602671106, "null": 0.4617398497776172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8508.json
index f3ea7d1c485..d8cef3e4138 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8508.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8508.json
@@ -1 +1 @@
-{"COMIRNATY": 2.3572455723294583, "HEXYON": 260.6918853920437, "MMRVAXPRO": 42.60356141210312, "SPIKEVAX": 3.847075015678275, "TOZINAMERAN": 2.868779132931291, "VAXZEVRIA": 1.4207827002550548}
\ No newline at end of file
+{"ARIPIPRAZOLE": 56.73320212124985, "null": 3.552462952055484}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8509.json
index 07b2fd41b86..c96e8a31e42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8509.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8509.json
@@ -1 +1 @@
-{"COMIRNATY": 2.416801000324359, "COVID19": 2.2753532858299885, "SPIKEVAX": 3.5853665329324613, "TOZINAMERAN": 1.7845210813797494, "VAXZEVRIA": 13.939786945130258}
\ No newline at end of file
+{"null": 0.93936999068891}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/851.json
index 628752b8410..048f42cf349 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/851.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/851.json
@@ -1 +1 @@
-{"IBRANCE": 9.281015349640894, "JAKAVI": 47.13475456926137, "RUXOLITINIB": 93.88774821125796}
\ No newline at end of file
+{"null": 2.2434296420663644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8510.json
index 029bb595b12..1292abdd109 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8510.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8510.json
@@ -1 +1 @@
-{"MMRVAXPRO": 188.5578073697158}
\ No newline at end of file
+{"COMIRNATY": 0.1656865634903838, "KEPPRA": 4.985847490371339, "PEGASYS": 1.7150418931700109, "VIAGRA": 19.319876776397145, "VIGABATRIN": 206.5678709662796, "null": 1.850907673261888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8511.json
index 05d1a7210ff..8585816d431 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8511.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8511.json
@@ -1 +1 @@
-{"COMIRNATY": 5.025671607600538, "SPIKEVAX": 3.110252584768116}
\ No newline at end of file
+{"null": 1.1246258934910878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8512.json
index 058f53ab5f3..79b69e21bd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8512.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8512.json
@@ -1 +1 @@
-{"COMIRNATY": 1.1274729944122928, "COVID19": 1.0532665668382208, "HEXYON": 551.143739752107, "MMRVAXPRO": 110.94639226178272, "SPIKEVAX": 2.163961480796769}
\ No newline at end of file
+{"null": 1.0033881114169}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8513.json
index dce5196381f..b49973be1eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8513.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8513.json
@@ -1 +1 @@
-{"BEXSERO": 3.959442749890447, "COMIRNATY": 4.2829443320332015, "COVID19": 1.1083882969204732, "FLUCELVAX": 6.60404947006523, "HEXYON": 14.862515432037831, "INFANRIX": 1.7960991784337648, "MENVEO": 10.109563158396892, "MMRVAXPRO": 3.3889141175212, "NIMENRIX": 4.978503019292488, "PREVENAR": 3.684474335846635, "SHINGRIX": 3.121030838091634, "SPIKEVAX": 9.50183620078729, "TOZINAMERAN": 1.4944749174627752, "VAXZEVRIA": 1.8242871288665856}
\ No newline at end of file
+{"null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8514.json
index af46f00e34c..04c99124262 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8514.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8514.json
@@ -1 +1 @@
-{"SPIKEVAX": 3.776076810247838}
\ No newline at end of file
+{"INSULIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8515.json
index 6c8ada063a1..8ccc7b2bc2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8515.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8515.json
@@ -1 +1 @@
-{"GARDASIL": 5.39448124161537, "HEXYON": 1511.2063477437218, "INFANRIX": 141.45240558382972, "MMRVAXPRO": 308.6592987071166, "PREVENAR": 114.20945933702082, "TWINRIX": 30.439838249201856}
\ No newline at end of file
+{"null": 1.5365841720830886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8516.json
index 75007c3a315..966c1dd8218 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8516.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8516.json
@@ -1 +1 @@
-{"COMIRNATY": 4.889528872062062, "COVID19": 1.7917765650485178, "MMRVAXPRO": 1.9547670086693392, "SHINGRIX": 1.8002779001631863, "SPIKEVAX": 2.303944388374126, "VAXZEVRIA": 7.978883126163369}
\ No newline at end of file
+{"COMIRNATY": 0.8221205229536399, "HUMALOG": 1.089228274716534, "PEGASYS": 4.439784482206279, "PEGINTERFERON": 6.866297589043155, "PEGINTRON": 7.8836263184468995, "SHINGRIX": 1.9028302198207456, "SILDENAFIL": 75.20215636705277, "SPIKEVAX": 0.4852053078591729, "SUTENT": 0.5331876349804952, "TOZINAMERAN": 0.4648273974837243, "VAXZEVRIA": 0.4358269877426817, "VIAGRA": 115.47809232654626, "ZOSTAVAX": 2.229846541355037, "null": 0.7068360635131922}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8517.json
index d12066e6693..e346e9fd882 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8517.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8517.json
@@ -1 +1 @@
-{"COMIRNATY": 4.340562251392951, "GARDASIL": 2.211264244502202, "MEPOLIZUMAB": 18.417433129844696, "NIMENRIX": 17.04662020251099, "SPIKEVAX": 2.489998353472764, "TOZINAMERAN": 7.229896800170886}
\ No newline at end of file
+{"null": 1.7686867308074297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8518.json
index 26493296561..1fa6dff8f1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8518.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8518.json
@@ -1 +1 @@
-{"COMIRNATY": 5.635636730344197, "SPIKEVAX": 5.359740093047969, "VAXZEVRIA": 2.081970808558284}
\ No newline at end of file
+{"PEGINTRON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8519.json
index ed860be2205..90fada2f889 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8519.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8519.json
@@ -1 +1 @@
-{"COMIRNATY": 2.527049262696335, "COVID19": 1.0723850413117748, "SPIKEVAX": 3.1837434837406797, "TOZINAMERAN": 2.906856411826692, "VAXZEVRIA": 7.566582122434965}
\ No newline at end of file
+{"null": 0.9567157319567168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/852.json
index 84a79964d91..e242542994a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/852.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/852.json
@@ -1 +1 @@
-{"OMALIZUMAB": 196.94243336374657, "SPIKEVAX": 4.153048058998574}
\ No newline at end of file
+{"ENTRESTO": 17.68778272181648, "null": 0.6895882792690293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8520.json
index 59e26941933..6daf86ef74d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8520.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8520.json
@@ -1 +1 @@
-{"HEXYON": 1036.1351899356696, "MMRVAXPRO": 300.3033382253412, "PREVENAR": 342.1343021457868}
\ No newline at end of file
+{"BEDAQUILINE": 27.34892358315133, "COMBIVIR": 15.585757400271092, "COMIRNATY": 0.2561076917659278, "PEGINTRON": 5.08671583400806, "TOZINAMERAN": 0.6059650847611241, "VAXZEVRIA": 0.2285659890408797, "VIAGRA": 24.46343675201418, "null": 1.1230797712280254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8521.json
index fecdd1faeb3..46c2538ccaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8521.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8521.json
@@ -1 +1 @@
-{"HEXYON": 1777.208906920939, "MMRVAXPRO": 179.99183316614966}
\ No newline at end of file
+{"null": 5.168424431654815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8522.json
index 8e9a2c4d344..59de4873846 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8522.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8522.json
@@ -1 +1 @@
-{"COMIRNATY": 6.890849864038543, "COVID19": 1.235204666987345, "SPIKEVAX": 1.5397355330927622, "TOZINAMERAN": 7.009088563103866}
\ No newline at end of file
+{"null": 0.7688781030861545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8523.json
index ad184aafb71..e25fec79a53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8523.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8523.json
@@ -1 +1 @@
-{"BEXSERO": 12.242806762004076, "COMIRNATY": 3.6868934586111, "COVID19": 1.3613959218879652, "GARDASIL": 1.6167795221075527, "MENVEO": 38.6015465631628, "MMRVAXPRO": 1.8441809252495849, "NIMENRIX": 8.306726101960674, "PREVENAR": 7.061710007891035, "SHINGRIX": 2.660334521140563, "SPIKEVAX": 4.373666528166975, "TOZINAMERAN": 1.6373082503822338, "VAXZEVRIA": 3.5706906183395297}
\ No newline at end of file
+{"COMIRNATY": 0.3959581067446278, "VAXZEVRIA": 0.4719048737645917, "ZOSTAVAX": 5.572653418533247, "null": 1.535269949252125}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8524.json
index cc3808f6bb7..37f565f86fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8524.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8524.json
@@ -1 +1 @@
-{"COVID19": 2.329395706370232, "SPIKEVAX": 5.815067105576863, "TOZINAMERAN": 3.34489649773022, "VAXZEVRIA": 1.5887827783519315}
\ No newline at end of file
+{"null": 0.8145643285262828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8525.json
index a400aaff8f7..0d49d3f7af6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8525.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8525.json
@@ -1 +1 @@
-{"COMIRNATY": 2.993634786888085, "COVID19": 4.935643704645565, "FLUCELVAX": 9.927866538282045, "MENVEO": 8.020744994118138, "NIMENRIX": 9.287959741683382, "NOT": 2.5961379245385032, "SHINGRIX": 5.729856469302089, "SPIKEVAX": 4.0641514444245015, "VAXZEVRIA": 2.2150069467076845}
\ No newline at end of file
+{"EXJADE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8526.json
index 0b49e1667a3..e92f07cf94e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8526.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8526.json
@@ -1 +1 @@
-{"COMIRNATY": 2.770746747398023, "VAXZEVRIA": 3.206284261144364}
\ No newline at end of file
+{"ALEMTUZUMAB": 3.0634723740884326, "AMIKACIN": 8.628884490105358, "AMINOSALICYLIC": 7.993482644255071, "ARAVA": 0.1606020337693349, "AUBAGIO": 16.354029406573662, "BEDAQUILINE": 13.441853436674988, "BETAFERON": 15.885276611415652, "CELLCEPT": 0.8668314569515175, "CICLOSPORIN": 0.6259585296009528, "CIMZIA": 2.067397141142286, "COMBIVIR": 4.191856692675621, "COMIRNATY": 0.9730005653730932, "COSENTYX": 0.5385839211605215, "CYMBALTA": 0.3604270786254562, "ENBREL": 0.9517951232496116, "ENTYVIO": 1.3956253581208014, "GARDASIL": 6.166319942328212, "HUMIRA": 1.551017814001276, "INTRONA": 7.712711717318518, "IPILIMUMAB": 6.291091398036157, "KALETRA": 1.6283200610914017, "KEPPRA": 0.7914809978408227, "KESIMPTA": 10.21881080861654, "KEYTRUDA": 3.2575266224668007, "KYMRIAH": 2.4056935949643994, "LEMTRADA": 5.321645901199993, "LEVOFLOXACIN": 1.4882380872522836, "MAVENCLAD": 12.251022364824635, "MEKINIST": 1.758100921582411, "METHOTREXATE": 1.21694768597781, "MODERNA": 0.8214404877161052, "PEGASYS": 2.159315863619944, "PEGINTRON": 5.74878954844395, "PLEGRIDY": 5.263842198407787, "REBETOL": 6.373349113214562, "ROACTEMRA": 1.6524654056302517, "SAXENDA": 1.667217135472968, "SHINGRIX": 1.253501793818085, "SIMPONI": 2.933663818050624, "SPIKEVAX": 0.5123744058601588, "STELARA": 1.154978109057227, "TASIGNA": 1.271321771969937, "TOZINAMERAN": 1.1107989877056312, "TWINRIX": 12.203871933097796, "VAXZEVRIA": 0.5896489654261761, "VFEND": 5.216255483140998, "VIAGRA": 3.170918457452134, "XOLAIR": 1.0378115720738854, "ZOSTAVAX": 1.1424225257434908, "null": 0.6586939214831671}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8527.json
index cd03f1e528c..c24ddd6122f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8527.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8527.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4689894665871606, "COVID19": 1.324079110829255, "HEXYON": 229.8750314901758, "MMRVAXPRO": 37.3490613321216, "SPIKEVAX": 4.449396973750255, "TOZINAMERAN": 1.979906323625832, "VAXZEVRIA": 1.409238295015806}
\ No newline at end of file
+{"COMBIVIR": 11.184288860664696, "COMIRNATY": 0.1491729608253386, "FENTANYL": 2.9415100199405213, "PEGASYS": 2.4748696296274693, "PEGINTERFERON": 9.950603839118072, "PEGINTRON": 8.783995469735185, "SPIKEVAX": 0.1102049315536972, "TELMISARTAN": 42.39028228996898, "VAXZEVRIA": 0.1619248294581118, "VFEND": 4.908754258348037, "VIAGRA": 4.502740865463051, "null": 1.5839948294182815}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8528.json
index 6a7155cd2be..899c92dc9ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8528.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8528.json
@@ -1 +1 @@
-{"COMIRNATY": 2.146884941059276}
\ No newline at end of file
+{"STALEVO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8529.json
index 6b62c1a3913..8981c2a21d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8529.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8529.json
@@ -1 +1 @@
-{"COMIRNATY": 3.2465589936346686, "COVID19": 2.458281015355784, "NIMENRIX": 12.758099906039234, "SPIKEVAX": 5.072045065794659, "VAXZEVRIA": 1.3648131049507124}
\ No newline at end of file
+{"JETREA": 2182.0966030865507, "VIGABATRIN": 3883.8639835737167}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/853.json
index 38fdb123300..159f2e73585 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/853.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/853.json
@@ -1 +1 @@
-{"IBRANCE": 17.46430699825248}
\ No newline at end of file
+{"AVANDIA": 7.269905223714561, "ELIQUIS": 20.841431674251403, "MEPOLIZUMAB": 8.8594125817728, "PLAVIX": 3.239597482420156, "null": 1.6573406448537251}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8530.json
index 19cf6aa36f2..f0aea34c3a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8530.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8530.json
@@ -1 +1 @@
-{"COMIRNATY": 6.150080386265568, "SPIKEVAX": 1.3119354389372615}
\ No newline at end of file
+{"BUPRENORPHINE": 42.8829442852114, "SUBOXONE": 64.06731827663016, "null": 2.7650686591268263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8531.json
index dc2a54a79c0..29687d6da65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8531.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8531.json
@@ -1 +1 @@
-{"COMIRNATY": 4.5454169849558825, "COVID19": 1.2673735846829282, "SPIKEVAX": 2.9523222063154257, "TOZINAMERAN": 3.7230479611713263, "VAXZEVRIA": 2.3380835123055044}
\ No newline at end of file
+{"COMIRNATY": 0.258514801039746, "null": 6.941429057685932}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8532.json
index 6b04e6ec409..1e5b86c3084 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8532.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8532.json
@@ -1 +1 @@
-{"COMIRNATY": 5.350382344891142, "COVID19": 2.252833548782102, "SPIKEVAX": 2.899476044892268, "TOZINAMERAN": 1.6511524590741118, "VAXZEVRIA": 2.758332995726885}
\ No newline at end of file
+{"null": 1.6707413842154883}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8533.json
index 2a7b22e7773..dc3c14ddd12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8533.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8533.json
@@ -1 +1 @@
-{"COMIRNATY": 4.685275853762176, "MENVEO": 65.08829983941715, "SHINGRIX": 4.963823471425084, "SPIKEVAX": 5.149752862700527, "VAXZEVRIA": 1.1834405238502468}
\ No newline at end of file
+{"COMIRNATY": 0.6613518399476455, "SPIKEVAX": 0.5702215682404147, "TOZINAMERAN": 1.955352440882538, "VAXZEVRIA": 2.7121443729374737, "null": 0.7019282230434047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8534.json
index 382910f69b6..c0e1f07ee81 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8534.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8534.json
@@ -1 +1 @@
-{"SPIKEVAX": 4.295542955474835}
\ No newline at end of file
+{"ABACAVIR": 2.075965350732973, "ACLIDINIUM": 5.240636219464246, "ADALIMUMAB": 7.326575543361769, "AIMOVIG": 0.4443867639220459, "ALIGN": 108.67658809148702, "ALIMTA": 2.75204136774328, "AMINOSALICYLIC": 62.15940815585522, "ANORO": 5.599558497368258, "ARAVA": 0.56811560123554, "AVAMYS": 33.359359073633925, "AZATHIOPRINE": 2.4286752659166777, "BEXTRA": 12.170827291552945, "BUDESONIDE": 40.82296899556298, "BUSULFAN": 1.0643593068262174, "CAPECITABINE": 1.027883388947948, "CASPOFUNGIN": 5.516021599530959, "CELLCEPT": 1.1541679974376775, "CHAMPIX": 0.3860998634048456, "CICLOSPORIN": 0.6593538124992419, "CIMZIA": 1.0439962679648251, "COMIRNATY": 0.0640982154843528, "COSENTYX": 8.807033773744232, "CYMBALTA": 0.3578792134090501, "CYTARABINE": 1.5120411477748852, "DACLATASVIR": 7.061174146273633, "DELAMANID": 10.854896403765474, "DEXAMETHASONE": 1.1705625942257516, "DOCETAXEL": 0.9018471270462886, "DUORESP": 16.000916268836836, "ELIQUIS": 0.3804939231034999, "ENTYVIO": 1.7315168097115916, "EPIVIR": 4.697492849660551, "ESBRIET": 0.7508169713547145, "GANCICLOVIR": 5.375922212651754, "GARDASIL": 0.1855757320770709, "HUMIRA": 0.8348284629506877, "HYDROCORTISONE": 1.5404477179867309, "IBRANCE": 0.3133207184737148, "INCIVO": 3.4666639284750143, "INCRUSE": 4.793885048519384, "JAKAVI": 0.8178049246051232, "JARDIANCE": 0.7608476909541299, "JORVEZA": 97.95356823430126, "KALETRA": 2.0490313041569874, "KEYTRUDA": 0.689279832760832, "LAMIVUDINE": 2.0457059839534777, "LEVOFLOXACIN": 0.9380347150189744, "LYRICA": 0.5789023289489209, "MEPOLIZUMAB": 1.5157764314627906, "METHOTREXATE": 1.522599440838616, "NEULASTA": 2.0160950685816665, "NEXAVAR": 0.2826547896799626, "NORVIR": 3.1838893230475063, "NUCALA": 2.9505223142673715, "OFEV": 0.9004285897680274, "OPDIVO": 1.0914693483994882, "OPSUMIT": 0.4772974507204394, "PEGASYS": 1.0380164544160628, "PEGINTERFERON": 2.384868751403672, "PEGINTRON": 0.668687253251079, "PLAVIX": 0.4199155105337265, "PREGABALIN": 17.077154894785256, "RELVAR": 16.891231761485606, "RINVOQ": 2.5117021592241957, "ROACTEMRA": 0.9035635452863158, "SIMPONI": 1.5369166606798583, "SPIKEVAX": 0.048927185470781, "STELARA": 0.7819162047170855, "STIVARGA": 0.9899752907104238, "SUTENT": 0.9211989551086804, "TOZINAMERAN": 0.1640033886606058, "TRELEGY": 7.310189186092027, "UMECLIDINIUM": 9.464098332735691, "VAXZEVRIA": 0.0790445798661227, "XELJANZ": 0.91431958483325, "ZOSTAVAX": 0.8804693184186423, "null": 0.786384920987595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8535.json
index c432a023762..928345c2e05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8535.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8535.json
@@ -1 +1 @@
-{"COMIRNATY": 11.956001955204387, "COVID19": 1.4104524126104825, "NIMENRIX": 2.793364032369446, "SPIKEVAX": 4.465612296887367}
\ No newline at end of file
+{"null": 1.3727476869860695}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8536.json
index 71a69633adc..a24316396f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8536.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8536.json
@@ -1 +1 @@
-{"COMIRNATY": 1.942573311507044, "SPIKEVAX": 14.535878247339587, "VAXZEVRIA": 1.4562602263576705}
\ No newline at end of file
+{"COMIRNATY": 8.234217289434964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8537.json
index 5e9ab6236dc..d0fade4892c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8537.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8537.json
@@ -1 +1 @@
-{"BEXSERO": 19.94983584023073, "COMIRNATY": 2.4822635967342523, "COVID19": 4.190805210094067, "GARDASIL": 1.4315205969265132, "MMRVAXPRO": 1.4094333641844965, "NIMENRIX": 2.783140459107506, "SPIKEVAX": 2.2159526604587776, "TOZINAMERAN": 10.541851363776289, "VAXZEVRIA": 2.317020581007881}
\ No newline at end of file
+{"COMIRNATY": 0.4655443597635859, "VAXZEVRIA": 3.003591766876835, "null": 0.4421923165512941}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8538.json
index dad7755c825..f8cd22aa2ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8538.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8538.json
@@ -1 +1 @@
-{"COMIRNATY": 5.17644447538072, "COVID19": 1.4930487070029723, "SHINGRIX": 1.728611867063502, "SPIKEVAX": 5.594706912012897, "TOZINAMERAN": 2.71175575432915, "VAXZEVRIA": 2.5027258729453004}
\ No newline at end of file
+{"null": 2.52965674176222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8539.json
index c9d24b95e7d..eea2459eb50 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8539.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8539.json
@@ -1 +1 @@
-{"COMIRNATY": 3.851190703815121}
\ No newline at end of file
+{"ABATACEPT": 0.7196721616798218, "ADALIMUMAB": 2.7393842836719133, "AERIUS": 3.3094461135480917, "AFINITOR": 0.5968025936817976, "AIMOVIG": 0.3357744171859891, "BENLYSTA": 0.605907087326497, "BRINTELLIX": 0.5978829404031977, "BUPRENORPHINE": 0.7109018014836281, "CABOMETYX": 1.455496592333807, "CHAMPIX": 0.3695975480701589, "CHLORHEXIDINE": 2.751138203065422, "CICLOSPORIN": 0.238588803811306, "CIMZIA": 1.0800115122357128, "CLOPIDOGREL": 0.4059975852475128, "COMIRNATY": 0.5872375237929287, "COSENTYX": 0.6487216927319784, "CYMBALTA": 0.3227845748398417, "ELIQUIS": 0.1874742985492075, "ENBREL": 0.6152559281928122, "ENTRESTO": 0.6134755786944055, "FORSTEO": 1.0897428204868342, "HUMALOG": 0.3921256047211357, "IBRANCE": 0.3546653936404511, "INLYTA": 2.357684248620034, "JARDIANCE": 0.3080348242320522, "LANTUS": 0.1754555719358417, "MEPOLIZUMAB": 0.681660751294068, "NEXAVAR": 0.4171887098896349, "ONCASPAR": 3.657221832604946, "PEGASYS": 0.5363998319797277, "QUTENZA": 4.59956394822805, "RELVAR": 3.714242304878363, "SHINGRIX": 0.5919283535094709, "SPIKEVAX": 0.4144895587613313, "SUBOXONE": 1.0661123851666896, "SUTENT": 6.408646533876267, "TELMISARTAN": 5.600585268935812, "TOZINAMERAN": 0.6918643647568526, "TRELEGY": 3.4765932251351, "VAXZEVRIA": 0.3069829245836806, "VOTRIENT": 1.0672887991674107, "XELJANZ": 0.4074677805984363, "null": 3.334284816981792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/854.json
index a48f3dec738..978a8eaa610 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/854.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/854.json
@@ -1 +1 @@
-{"AMBRISENTAN": 7.034340330039236, "APIDRA": 1.3469729623761677, "AUBAGIO": 1.514727417109517, "BENLYSTA": 2.5178329136492925, "CHAMPIX": 1.463704879942372, "COMIRNATY": 1.3945597536984968, "ELIQUIS": 1.1616561013012143, "ENBREL": 1.3262005522907834, "EXFORGE": 1.0387266328963716, "GARDASIL": 2.327442938541424, "HIZENTRA": 1.2947235438272078, "JARDIANCE": 1.0104885219128428, "LANTUS": 2.98109301987898, "LYRICA": 2.2220456618092865, "NUCALA": 1.4723193041167566, "PEGINTRON": 1.043658638717727, "SHINGRIX": 7.999370464617441, "SIMPONI": 3.3786508074515447, "SPIKEVAX": 1.866209885858558, "SUTENT": 1.3068322002163852, "TOZINAMERAN": 1.2123714210947458, "TWINRIX": 2.017999925391984, "VAXZEVRIA": 1.2324308480623054, "XELJANZ": 1.175310948720962, "XOFIGO": 2.886133874536462, "XTANDI": 2.6162967607047487}
\ No newline at end of file
+{"null": 0.9004185235913372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8540.json
index 5ee92000c5d..4e70ba738c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8540.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8540.json
@@ -1 +1 @@
-{"COMIRNATY": 4.687358057553326}
\ No newline at end of file
+{"AIMOVIG": 0.9331814421561594, "ARAVA": 0.17332121653408, "BUDESONIDE": 0.9352222513405436, "CELLCEPT": 1.443185530675714, "CHAMPIX": 1.0281277523843146, "CICLOSPORIN": 2.5754497234887324, "CIMZIA": 1.331293472362839, "CLOPIDOGREL": 1.3985706513452818, "COMIRNATY": 0.2664360762526987, "COSENTYX": 2.126075622252371, "CYMBALTA": 0.8442363465830551, "CYTARABINE": 3.194451962349238, "DARUNAVIR": 15.21619191116634, "DEXAMETHASONE": 1.5275637544170309, "ELIQUIS": 0.863424910990388, "ENBREL": 1.5958104767928902, "HYDROCORTISONE": 9.219393402718625, "IBRANCE": 2.292615933401045, "INCIVO": 2.899656222909162, "INLYTA": 2.5187622762524584, "KEYTRUDA": 0.9236895541904436, "METHOTREXATE": 1.4552264554726135, "NEXAVAR": 1.80999874127508, "NUCALA": 2.76781797281798, "PEGASYS": 1.139701495999751, "PEGINTERFERON": 3.681851384405282, "RITUXIMAB": 1.5578881974524097, "SPIKEVAX": 0.1306824415984336, "SUTENT": 5.316941268189884, "TOZINAMERAN": 0.5704076165496539, "VAXZEVRIA": 0.1396484740116519, "VFEND": 1.6808425439845818, "XELJANZ": 0.845507559132489, "ZOSTAVAX": 1.196069399012012, "ZYPREXA": 0.9491461941476548, "null": 1.472148786782486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8541.json
index 54148a98a27..a503a705637 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8541.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8541.json
@@ -1 +1 @@
-{"COMIRNATY": 2.138038671763361, "GARDASIL": 8.801688959630235, "MMRVAXPRO": 19.86285678898617, "TOZINAMERAN": 2.622805498291795, "VAXZEVRIA": 2.0588415454860884}
\ No newline at end of file
+{"COMIRNATY": 1.7323981410086453, "SPIKEVAX": 0.5953817047398522, "SYCREST": 163.14584172802412, "VAXZEVRIA": 0.3732522801324605, "null": 1.544966902482822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8542.json
index 985dad91643..84d099882cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8542.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8542.json
@@ -1 +1 @@
-{"BEXSERO": 7.991036305563466, "COMIRNATY": 5.873642047094477, "COVID19": 1.0362127206551746, "INFANRIX": 4.47265674319959, "MENVEO": 47.43242298537725, "MMRVAXPRO": 6.734524941574374, "NIMENRIX": 8.988282594334297, "ROTATEQ": 1.6913601865666728, "SHINGRIX": 2.3788726115111585, "SPIKEVAX": 4.7061445608945, "VAXZEVRIA": 2.44147216210118}
\ No newline at end of file
+{"BUDESONIDE": 1.945331095182284, "CIMZIA": 1.6779818219094529, "COMIRNATY": 0.2938476677435392, "COSENTYX": 7.323403183754044, "JARDIANCE": 6.741130600675347, "KEYTRUDA": 1.3846683889323903, "PEGASYS": 3.160035187627252, "RELVAR": 38.85855409399144, "SIMPONI": 2.339390974892345, "SPIKEVAX": 0.0878014727246416, "SUTENT": 1.2203193591525177, "TRELEGY": 6.1289705429192685, "XELJANZ": 1.323946123586318, "null": 1.7093244312322269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8543.json
index c0b26ebf1ff..314e55022cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8543.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8543.json
@@ -1 +1 @@
-{"COMIRNATY": 6.947657335236569, "COVID19": 2.3106827761968924, "ELASOMERAN": 2.883699324443119, "FENDRIX": 4.011770971260221, "FLUCELVAX": 3.617670764971858, "HEXYON": 1.6167098395528372, "MENVEO": 2.1860909693921133, "MMRVAXPRO": 1.8696885730490196, "NIMENRIX": 2.037475371541233, "SHINGRIX": 1.6594283995089132, "SPIKEVAX": 3.6096616179270713, "TOZINAMERAN": 2.0383860176818103, "VAXZEVRIA": 3.398860271003768}
\ No newline at end of file
+{"TRACLEER": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8544.json
index a76ec3036e4..67470c302dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8544.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8544.json
@@ -1 +1 @@
-{"COMIRNATY": 1.607967779323738, "SPIKEVAX": 2.3307675183328644}
\ No newline at end of file
+{"ABATACEPT": 0.2290644102975937, "ACLASTA": 11.519342555804696, "AFINITOR": 1.2679445189041354, "AIMOVIG": 0.4055664726039631, "ALEMTUZUMAB": 2.2170214169128597, "ANAKINRA": 1.536078605713305, "ARAVA": 0.2642561667842338, "ASPARAGINASE": 11.192740755611666, "AUBAGIO": 1.731154136277789, "AVASTIN": 0.6334908255984014, "BENLYSTA": 0.971496424136381, "CELLCEPT": 0.8807976536097926, "CHAMPIX": 0.5823946015856233, "CICLOSPORIN": 0.8785144157961143, "CIMZIA": 0.8252417665342573, "COMIRNATY": 2.394962996477421, "COSENTYX": 3.5862150322763946, "CYMBALTA": 0.270391562285009, "CYTARABINE": 2.2722103677390884, "DEXAMETHASONE": 1.0170225962010788, "ELIQUIS": 0.146865529705694, "ENBREL": 0.3522025228470193, "ENTYVIO": 0.8561583124185956, "FASENRA": 1.2986803162006535, "FASLODEX": 0.6710325199963367, "GARDASIL": 0.5072723968747164, "HUMIRA": 2.769306108257209, "IBRANCE": 1.5249208026809136, "JAKAVI": 1.1581715788232638, "KESIMPTA": 9.870295650029282, "KEYTRUDA": 0.2258370421055179, "LEMTRADA": 1.9602415632272157, "LUTATHERA": 6.461218656891535, "MAVENCLAD": 18.49884000833011, "METHOTREXATE": 2.115892754861277, "MMRVAXPRO": 0.3808036410821886, "MODERNA": 2.801354546156851, "NAGLAZYME": 1.969900948184911, "OCRELIZUMAB": 1.1504411617795711, "OMALIZUMAB": 1.0722319947968872, "PEGASYS": 1.4181507346082407, "PEGINTERFERON": 1.661133705920628, "PEGINTRON": 0.3691896373324005, "REMICADE": 1.8521640894615568, "RINVOQ": 10.63158919847345, "RITUXIMAB": 0.974352571237355, "ROACTEMRA": 3.2167770115129266, "SHINGRIX": 9.719624967156149, "SIMPONI": 3.4612731365721494, "SOLIRIS": 0.5692756941638315, "SPIKEVAX": 1.6282463678871044, "STELARA": 1.2536505328425662, "SUTENT": 0.6638928465905676, "TOZINAMERAN": 1.075356813781896, "TREMFYA": 1.993289299358706, "TWINRIX": 1.3488973822953547, "UPADACITINIB": 14.211142165000236, "VAXZEVRIA": 1.6404108783786973, "XELJANZ": 2.9014939263670025, "XOLAIR": 0.9582965225209692, "ZOSTAVAX": 3.810263394313151, "null": 0.259375639707961}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8545.json
index b7dc390aa66..cade53914b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8545.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8545.json
@@ -1 +1 @@
-{"COMIRNATY": 7.746249301463012, "COVID19": 1.5424294436999104, "SPIKEVAX": 2.19987097405362, "TOZINAMERAN": 2.4717160890073604, "VAXZEVRIA": 2.1647352967108766}
\ No newline at end of file
+{"COMIRNATY": 1.7743936857261693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8546.json
index 400bfa4580d..e8ee2fd7329 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8546.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8546.json
@@ -1 +1 @@
-{"COMIRNATY": 1.4012622600913014, "SPIKEVAX": 16.638904428226112}
\ No newline at end of file
+{"BENLYSTA": 7.128244385303307, "CIMZIA": 4.2134120977346186, "COMIRNATY": 0.1347773926033675, "IBRANCE": 5.227363209236029, "PEGASYS": 3.1820411826383297, "SIMPONI": 7.15911562746266, "STELARA": 2.670479374240032, "SUTENT": 2.229445226914221, "XELJANZ": 4.85542441039379, "null": 0.896664653487014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8547.json
index 51bd86509b2..d901989212b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8547.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8547.json
@@ -1 +1 @@
-{"COMIRNATY": 5.517383901157182, "FLUCELVAX": 3.257510176229579, "HEXYON": 35.2598687676903, "INFANRIX": 3.633828503933065, "MENVEO": 2.9704376801071093, "MMRVAXPRO": 6.016484327402222, "PREVENAR": 4.205430539214654, "SHINGRIX": 1.6856551861605085, "SPIKEVAX": 9.211307139784228, "TOZINAMERAN": 1.12903823579512, "TWINRIX": 1.1985350043185607, "VAXZEVRIA": 1.3444825843246182}
\ No newline at end of file
+{"CICLOSPORIN": 4.445670624118467, "COMIRNATY": 1.1202392233395904, "ESOMEPRAZOLE": 56.01994590351213, "PEGASYS": 2.498449708420172, "SPIKEVAX": 0.4463558533128402, "TOZINAMERAN": 2.44318977268338, "VAXZEVRIA": 0.4267949569851069, "null": 0.4039266008666013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8548.json
index dc1bc3285c5..acdf7dbbee2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8548.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8548.json
@@ -1 +1 @@
-{"COMIRNATY": 1.40254559615763, "SPIKEVAX": 3.384164207232451}
\ No newline at end of file
+{"null": 0.2977198257618891}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8549.json
index ffef774afd5..c66dd688a3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8549.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8549.json
@@ -1 +1 @@
-{"COMIRNATY": 1.8804470686185, "COVID19": 1.994908997615144, "HEXYON": 19.683592590916295, "MMRVAXPRO": 6.036000036173157, "NIMENRIX": 1.9935800783223592, "SHINGRIX": 2.357277570363777, "SPIKEVAX": 12.846320600044182, "TOZINAMERAN": 3.1303716699667103, "VAXZEVRIA": 1.13869244031994, "ZOSTAVAX": 2.068398244515403}
\ No newline at end of file
+{"AP": 1806.993202921764, "CICLOSPORIN": 3.302875716918216, "COMIRNATY": 0.126758927986732, "DEXAMETHASONE": 4.366414162621556, "FENTANYL": 7.296197566074242, "IBUPROFEN": 3.970336670804131, "KEYTRUDA": 2.842132659033052, "LYRICA": 4.394531767096284, "NEXAVAR": 6.173828220541467, "STIVARGA": 5.666083055556985, "null": 3.008011009882814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/855.json
index 55bd2f3279c..959f9ccf5b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/855.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/855.json
@@ -1 +1 @@
-{"ABILIFY": 2.1206745283380566, "ARIPIPRAZOLE": 3.2742267529208524, "AVAMYS": 1.4233916352474782, "BRIVARACETAM": 31.83180048056962, "BRIVIACT": 28.10895719829128, "BUPRENORPHINE": 1.8857959190396456, "CANNABIDIOL": 115.3863953710028, "CHAMPIX": 3.3111966839362625, "CLOPIDOGREL": 2.3996863199813623, "COMTAN": 7.093137508086747, "EBIXA": 21.011946629007557, "ENTACAPONE": 7.937667586832355, "FYCOMPA": 12.374557642448412, "HUMIRA": 1.0593160325189883, "KAFTRIO": 17.599291055584022, "KALETRA": 2.563454208762449, "KEPPRA": 17.139801753794504, "LACOSAMIDE": 8.239082236076753, "LEVETIRACETAM": 24.082626939401504, "LEVODOPA": 5.929558998271033, "LYRICA": 2.403006636835625, "MELATONIN": 4.079860722551242, "MMRVAXPRO": 1.94561241591405, "OLANZAPINE": 3.74630776013136, "PREGABALIN": 3.819263581851737, "SIFROL": 16.669319252473922, "STALEVO": 3.3670274828395783, "SUBOXONE": 2.2193967604555214, "TAMIFLU": 1.828745564500908, "VIMPAT": 3.726300388674943, "ZYPREXA": 2.513334593176341, "null": 2.802126672761681}
\ No newline at end of file
+{"AFINITOR": 1.4802793655846134, "ARANESP": 2.2526262091907507, "AVANDIA": 4.580170668540155, "CLOPIDOGREL": 3.8155777000459272, "COMIRNATY": 0.1908962962798089, "ELIQUIS": 1.65786671307958, "ENTRESTO": 9.979374345995724, "EXFORGE": 4.628532070591958, "FORSTEO": 1.6931555247910604, "MIDAZOLAM": 5.580270325501885, "NAGLAZYME": 21.161389535196328, "SPIKEVAX": 0.1572848330164701, "SPIRONOLACTONE": 11.26172231608694, "VAXZEVRIA": 0.0596457745140583, "XOLAIR": 1.4930608267364336, "ZOMETA": 26.34132372946341, "ZOSTAVAX": 1.624481735730011, "null": 2.3717332530022084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8550.json
index d9a48d45f20..60b47f4947d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8550.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8550.json
@@ -1 +1 @@
-{"BEXSERO": 2.962587909400165, "COMIRNATY": 4.016720724803783, "COVID19": 1.6521716640143875, "ELASOMERAN": 5.808806897481141, "INFANRIX": 4.933438120595101, "MENVEO": 4.241963285669499, "MMRVAXPRO": 4.148795048017177, "NIMENRIX": 3.737306260697042, "PREVENAR": 2.2693349546213417, "SHINGRIX": 2.465968547612385, "SPIKEVAX": 8.15299973998501, "TWINRIX": 1.7418599376782729, "VAXZEVRIA": 3.3190131160202183}
\ No newline at end of file
+{"null": 1.80659874257022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8551.json
index 35dde92bb90..54d5e96210f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8551.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8551.json
@@ -1 +1 @@
-{"COMIRNATY": 2.347258077801965}
\ No newline at end of file
+{"AFINITOR": 1.7337256972575914, "AIMOVIG": 1.3253430234527124, "ARAVA": 0.1153767025065111, "AUBAGIO": 0.9400742720485684, "BENLYSTA": 1.995128773274872, "BUPRENORPHINE": 1.8326159253718044, "CABOMETYX": 2.29833029336413, "CHAMPIX": 1.858714318217618, "COMIRNATY": 0.7025659926033653, "COSENTYX": 1.0047434711333796, "CYMBALTA": 0.3569834540225021, "ELIQUIS": 0.3229134715127962, "GARDASIL": 0.9409034062718868, "IBRANCE": 2.58484936155461, "IBUPROFEN": 1.6500815674799074, "IMATINIB": 8.27829216455867, "INLYTA": 4.531119554012507, "KEPPRA": 0.4807040027211576, "KEYTRUDA": 0.5015931558765027, "PEGASYS": 3.297024115683356, "ROACTEMRA": 2.6376016303247254, "SHINGRIX": 3.584054439747989, "SPIKEVAX": 0.6102362352513389, "SUBOXONE": 1.2336510888976235, "SUTENT": 8.636912442747827, "TASIGNA": 1.5957273594742167, "TOZINAMERAN": 0.6658516803807072, "VAXZEVRIA": 0.5564613607473403, "VOTRIENT": 1.3208615382969684, "XELJANZ": 0.6537241548585155, "null": 1.579568639972588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8552.json
index 2ba62148adb..9f4d03e1921 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8552.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8552.json
@@ -1 +1 @@
-{"COMIRNATY": 2.280201205703236, "MMRVAXPRO": 34.217966005721514, "SPIKEVAX": 1.728415392205192}
\ No newline at end of file
+{"STALEVO": 96.12341708593657, "null": 2.8579957162534964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8553.json
index 64f68ff85de..6475cbdda50 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8553.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8553.json
@@ -1 +1 @@
-{"BEXSERO": 2.979605448560456, "COMIRNATY": 4.960439116185119, "COVID19": 1.665177938683581, "FLUCELVAX": 7.6327432351408895, "HEXYON": 7.553123867549315, "INFANRIX": 3.555226572751404, "MENVEO": 5.737976516164305, "MMRVAXPRO": 5.4202125544230855, "NIMENRIX": 4.235572733716167, "PREVENAR": 2.9182893696500334, "SHINGRIX": 2.5347762362199484, "SPIKEVAX": 7.094089261821529, "TOZINAMERAN": 1.745973049608732, "VAXZEVRIA": 1.8068254955843712}
\ No newline at end of file
+{"COMIRNATY": 0.2572147722219238, "KEYTRUDA": 1.3340665601255888, "MMRVAXPRO": 5.925652820205065, "PANTOPRAZOLE": 7.87819038654952, "SPIKEVAX": 0.2600705134027883, "SUTENT": 1.974121234772083, "TOZINAMERAN": 0.5819335759578694, "VAXZEVRIA": 0.3681926644536836, "null": 2.841344699112302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8554.json
index ca6c38dbdfb..056bd857304 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8554.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8554.json
@@ -1 +1 @@
-{"COMIRNATY": 4.2791271038711365}
\ No newline at end of file
+{"CICLOSPORIN": 1.903304953237057, "COMIRNATY": 0.4286128184917257, "SPIKEVAX": 0.1226507968872816, "SUTENT": 4.039529773797027, "TOZINAMERAN": 0.3032271152900739, "VAXZEVRIA": 0.1731328210735072, "null": 3.284325009741037}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8555.json
index df091a0572d..eec54332002 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8555.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8555.json
@@ -1 +1 @@
-{"COMIRNATY": 3.569297145616372}
\ No newline at end of file
+{"COMIRNATY": 0.1675394151419688, "SUTENT": 4.4912474570983525, "VAXZEVRIA": 0.240279699194306, "null": 2.655999033726152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8556.json
index 58d6917787d..848c2b0dd3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8556.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8556.json
@@ -1 +1 @@
-{"COMIRNATY": 2.2097876373299057, "MMRVAXPRO": 3.3470804440743254, "SPIKEVAX": 9.8804098336149, "TOZINAMERAN": 3.875361716620084}
\ No newline at end of file
+{"null": 2.207018844802872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8557.json
index 207bd447db0..d7e86d4cbc7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8557.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8557.json
@@ -1 +1 @@
-{"COMIRNATY": 1.6109612288744009, "MMRVAXPRO": 87.9787336902428, "SPIKEVAX": 2.284806062540618, "TOZINAMERAN": 1.8857700622904583, "ZOSTAVAX": 4.524481850795033}
\ No newline at end of file
+{"null": 0.4978747129012615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8558.json
index 191894d90f9..9bb980559d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8558.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8558.json
@@ -1 +1 @@
-{"COMIRNATY": 2.805225226235806, "COVID19": 1.3432297189253477, "FLUCELVAX": 8.159192504145052, "MENVEO": 15.74673184308442, "MMRVAXPRO": 1.0982034122243676, "NIMENRIX": 6.25805666134014, "SHINGRIX": 3.654581646572177, "SPIKEVAX": 8.898443574370981, "TOZINAMERAN": 2.798519888614446, "VAXZEVRIA": 3.503973865190762, "ZOSTAVAX": 1.0596010265576057}
\ No newline at end of file
+{"AFINITOR": 5.9993256640854415, "AIMOVIG": 0.2749057044219115, "ANORO": 2.1225586142702206, "APREPITANT": 1.6227202252541524, "ARAVA": 1.1734673067905736, "AVASTIN": 1.0693483919405935, "BEVACIZUMAB": 1.9721209560461688, "BRAFTOVI": 0.9980962975166778, "CABOMETYX": 4.215562769272423, "CELLCEPT": 0.3354232191013926, "CHAMPIX": 0.7065829804947952, "CICLOSPORIN": 0.3144745563304095, "CIMZIA": 0.1740691112095344, "CLOPIDOGREL": 0.5186281272971468, "COMIRNATY": 0.3311300151702384, "COSENTYX": 1.7121122755436875, "CYMBALTA": 0.4130677264781889, "CYTARABINE": 0.6419879473947336, "DEXAMETHASONE": 2.0630799376470965, "ELIQUIS": 0.2831865117094078, "ENBREL": 0.859510241977413, "EXJADE": 0.5055350899494457, "FASLODEX": 1.1588881732781575, "FORSTEO": 0.3427976320695082, "GARDASIL": 0.1842568250712476, "HERCEPTIN": 1.941191872396056, "HYDROCORTISONE": 0.8602032357458931, "IBRANCE": 4.754037759923496, "IBUPROFEN": 0.4102774191060714, "INCIVO": 2.1455777641952323, "INLYTA": 7.741015213140715, "IRINOTECAN": 1.736690892111498, "JANUMET": 0.3898575765455666, "JARDIANCE": 0.2254001995925815, "KEPPRA": 0.1900422397682117, "KEYTRUDA": 0.6040621037914785, "KISQALI": 1.2689481703031895, "LENVIMA": 1.8809146231639504, "MEKINIST": 0.6078480621858398, "MEPOLIZUMAB": 0.4405094058446812, "METHOTREXATE": 0.6439304205593771, "MMRVAXPRO": 0.3658642194666454, "NEULASTA": 3.890357200295511, "NEXAVAR": 2.1853232110713425, "OCALIVA": 3.645594118980828, "OCRELIZUMAB": 0.7797982654000079, "PEGASYS": 1.8311712553178772, "PEGINTERFERON": 1.167753371332649, "PEGINTRON": 1.2233013985783103, "PLAVIX": 0.2043861711865591, "RELVAR": 9.450982469993644, "ROACTEMRA": 0.7081029723145024, "SHINGRIX": 0.4469803434829036, "SPIKEVAX": 0.323826901693905, "SPRYCEL": 0.5914437488823777, "STELARA": 0.1858440352724179, "STIVARGA": 2.9663636300145666, "SUBOXONE": 0.9646320959048288, "SUTENT": 19.96951294766144, "TAGRISSO": 1.2504905544535998, "TORISEL": 3.0025155885227512, "TOZINAMERAN": 0.7950777418302538, "TRELEGY": 2.4979797348347144, "UMECLIDINIUM": 8.399413138773674, "VAXZEVRIA": 0.4924299273790248, "VOTRIENT": 2.1067785853905527, "XELJANZ": 0.9987902012335774, "null": 1.667631386152738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8559.json
index 73bd203dc51..a11e8d6604f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8559.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8559.json
@@ -1 +1 @@
-{"COMIRNATY": 3.0333519683017856, "SPIKEVAX": 14.240635620540903, "TOZINAMERAN": 1.0989645764195497}
\ No newline at end of file
+{"null": 4.906797623478453}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/856.json
index e897528c30e..886ac0aff67 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/856.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/856.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 96.24331586754238, "null": 1.1495562290499932}
\ No newline at end of file
+{"AVANDIA": 18.602610553937968, "ELIQUIS": 7.419259604392884, "JARDIANCE": 6.086296231391503, "LANTUS": 3.091001306575436, "null": 1.1588316928100793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8560.json
index f17e6adf2f1..2b70a90e6bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8560.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8560.json
@@ -1 +1 @@
-{"GARDASIL": 88.77815959694844, "SPIKEVAX": 4.045565735356236}
\ No newline at end of file
+{"null": 1.1188146268798724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8561.json
index eb384e8b818..a28496b0efd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8561.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8561.json
@@ -1 +1 @@
-{"null": 2.8576095853763683}
\ No newline at end of file
+{"COMIRNATY": 0.8007583663741731, "RITUXIMAB": 1.771125988390068, "SPIKEVAX": 0.2028136864356086, "TOZINAMERAN": 0.6230762538617206, "VAXZEVRIA": 0.1401816901832829, "XOLAIR": 1.6010279491408252, "null": 6.917975136345207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8562.json
index 92dd207b456..eea39421dec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8562.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8562.json
@@ -1 +1 @@
-{"null": 4.9387811580724525}
\ No newline at end of file
+{"COMIRNATY": 0.7211498389798829, "null": 1.5172200568503411}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8563.json
index bb6318706e0..481d58a8b7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8563.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8563.json
@@ -1 +1 @@
-{"KEPPRA": 109.90293221953046}
\ No newline at end of file
+{"ENBREL": 13.726201461261349, "IBRANCE": 10.913323736566308, "XELJANZ": 6.935425797341101, "null": 1.0277369100229516}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8564.json
index 19545bc7327..37f92659366 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8564.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8564.json
@@ -1 +1 @@
-{"JARDIANCE": 32.85275363247904}
\ No newline at end of file
+{"HARVONI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8565.json
index 7c27c546dac..5a45fa881a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8565.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8565.json
@@ -1 +1 @@
-{"COVID19": 3.1231704019232844}
\ No newline at end of file
+{"HIZENTRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8566.json
index ceda5f7b263..9c10ee6c2b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8566.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8566.json
@@ -1 +1 @@
-{"ADALIMUMAB": 11.706471024861564, "ALIGN": 164.720966623618, "AMINOSALICYLIC": 87.03466527243312, "AVAMYS": 45.67737894435127, "BUDESONIDE": 62.14163161807597, "ELLAONE": 95.53899126990868, "ESMYA": 13.615477879323098, "ISENTRESS": 2.997688628708564, "KAFTRIO": 2.264826345714297, "OVITRELLE": 21.034741252317108, "PREGABALIN": 25.111935198961216}
\ No newline at end of file
+{"null": 2.566026419329083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8567.json
index 51ad67124c9..de550285bad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8567.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8567.json
@@ -1 +1 @@
-{"null": 1.709625027998407}
\ No newline at end of file
+{"IPILIMUMAB": 162.43734978402895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8568.json
index 9c873571f0e..7a23f2df232 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8568.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8568.json
@@ -1 +1 @@
-{"null": 1.6406247505359015}
\ No newline at end of file
+{"COMIRNATY": 0.1449198753898798, "SUTENT": 4.658957808793553, "null": 2.7456638735999825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8569.json
index 31f75637fa3..e19ee8a31c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8569.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8569.json
@@ -1 +1 @@
-{"ADALIMUMAB": 26.04619129250113, "ALIGN": 351.0289539109318, "AMINOSALICYLIC": 206.98563694845055, "AVAMYS": 103.09892772177292, "BUDESONIDE": 168.708486554049, "PREGABALIN": 54.33823920804201}
\ No newline at end of file
+{"POSACONAZOLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/857.json
index a0578305ac7..10a7153051d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/857.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/857.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.4420580686332678, "CICLOSPORIN": 34.682646402431935, "COSENTYX": 5.472421978327979, "TOZINAMERAN": 1.306045825151028}
\ No newline at end of file
+{"ZOSTAVAX": 9.830322229263365, "null": 1.5955303555846685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8570.json
index ef909c03f21..b4c1a8b48ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8570.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8570.json
@@ -1 +1 @@
-{"ARAVA": 32.71066964142666}
\ No newline at end of file
+{"JARDIANCE": 42.50487069535817, "null": 0.3992861189850491}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8571.json
index fcf49069b5d..9d478281154 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8571.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8571.json
@@ -1 +1 @@
-{"ARIXTRA": 4.369567826302657, "BRINTELLIX": 1.8152771516727075, "COMIRNATY": 1.7969453878709671, "COVID19": 1.732692971612214, "ELIQUIS": 2.139822364305374, "ELLAONE": 85.60030502460712, "ENOXAPARIN": 2.632437635088713, "ESMYA": 10.216193869335347, "EVISTA": 2.554002326355911, "EVRA": 20.724463402346466, "FASLODEX": 1.021464064291891, "FIRDAPSE": 1.117984677913722, "LIXIANA": 4.409942861292236, "MISOPROSTOL": 25.645141802749496, "PLAVIX": 1.4674349491214167, "RYEQO": 13.048797638803364, "SPIKEVAX": 1.120073786063821, "SUBOXONE": 1.474524877732352, "TOZINAMERAN": 2.968841611225828, "XARELTO": 8.649417851682612, "null": 1.247006271269986}
\ No newline at end of file
+{"COMIRNATY": 0.3864704771788305, "FORXIGA": 23.10434468443439, "JARDIANCE": 19.36559452878269, "KAFTRIO": 32.5590485958551, "MMRVAXPRO": 9.51702650626466, "SPIKEVAX": 0.2527329269351064, "TOZINAMERAN": 0.5448203582670609, "VAXZEVRIA": 0.1373995834744131, "null": 0.9984886298364628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8572.json
index 694d609e728..207ba3ddc7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8572.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8572.json
@@ -1 +1 @@
-{"COSENTYX": 17.162057805852516, "FORXIGA": 41.36237883510333, "GARDASIL": 1.6031491755871112, "IRON": 24.78797810159916, "JARDIANCE": 36.94988496707706, "METHOTREXATE": 4.382401532358941, "PEGASYS": 1.2823377213217777, "SIMPONI": 3.3530464162927425, "XELJANZ": 2.2908939980981144, "ZOSTAVAX": 2.0808275578654354, "ZYPREXA": 1.560295200099494, "null": 1.0557409187805256}
\ No newline at end of file
+{"null": 4.40329870614908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8573.json
index 33d57ffa169..abc330829fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8573.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8573.json
@@ -1 +1 @@
-{"null": 1.9937791228351505}
\ No newline at end of file
+{"null": 0.3805458436018102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8574.json
index b2a3f9b575d..465c5ebbde7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8574.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8574.json
@@ -1 +1 @@
-{"null": 1.7555432159887274}
\ No newline at end of file
+{"BUSULFAN": 10.20224886167839, "CANCIDAS": 40.14281119641697, "COMIRNATY": 0.2118877755246259, "DEXAMETHASONE": 3.031715278889859, "ELIQUIS": 1.412907460714054, "HUMALOG": 1.9640727500722592, "REVATIO": 8.35955780544161, "SPIKEVAX": 0.1434974259046984, "SUTENT": 8.207036630176999, "TOZINAMERAN": 0.3547154637882291, "VAXZEVRIA": 0.0991832580218679, "null": 0.8853879489456374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8575.json
index 501c30abc39..630b14449c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8575.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8575.json
@@ -1 +1 @@
-{"TOZINAMERAN": 1.988009348005598}
\ No newline at end of file
+{"COMIRNATY": 0.348615012960918, "null": 0.990357914416916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8576.json
index ed9ef872cca..a7be0cd9a72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8576.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8576.json
@@ -1 +1 @@
-{"COMIRNATY": 1.5124789958617524}
\ No newline at end of file
+{"VAXZEVRIA": 0.4205190952786194, "ZOSTAVAX": 19.44100643152345, "null": 3.659150050492697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8577.json
index 050c5a0a761..88649829b26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8577.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8577.json
@@ -1 +1 @@
-{"CUBICIN": 21.82925127112264, "CYTARABINE": 5.785532944490518, "null": 14.45352933436712}
\ No newline at end of file
+{"AFINITOR": 2.239503995073812, "ALEMTUZUMAB": 4.228648435678491, "ALIMTA": 6.0488465658707575, "ARAVA": 0.2235803584887919, "BUSULFAN": 2.6015772897427376, "CELLCEPT": 1.8616803905906305, "CICLOSPORIN": 3.2185311096631986, "CIMZIA": 1.3075123071111785, "CLOPIDOGREL": 0.8159274998462936, "COMIRNATY": 0.2377431442958874, "CUBICIN": 23.709829370286045, "CYTARABINE": 2.5397925576383256, "ELIQUIS": 0.4455240760115727, "ENTYVIO": 3.441263722879807, "FASENRA": 4.014665675776367, "HUMIRA": 1.9485533325479296, "IPILIMUMAB": 3.560433136185261, "JAKAVI": 1.9989382455467244, "KALETRA": 3.4971438846116607, "KEYTRUDA": 15.58134444401968, "METHOTREXATE": 3.811183264613148, "OPDIVO": 12.062849410281848, "PEGASYS": 1.2690652321366898, "PEGINTERFERON": 3.297238594525865, "PEGINTRON": 1.4839240871060764, "PEMBROLIZUMAB": 12.522191324237964, "RAPAMUNE": 16.672601347505243, "RINVOQ": 2.358659241082788, "ROACTEMRA": 3.0774313535936524, "SIMPONI": 3.6275679526940032, "SPIKEVAX": 0.092894652183115, "STELARA": 1.446577541826186, "TOCILIZUMAB": 15.905661834756629, "TOZINAMERAN": 0.152602104770897, "XOLAIR": 0.9428001306508016, "null": 1.1226372716374469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8578.json
index 6c4dcc8e0b0..697a7826571 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8578.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8578.json
@@ -1 +1 @@
-{"BUSULFAN": 45.24553595218547, "TEMOZOLOMIDE": 133.89355413218908}
\ No newline at end of file
+{"BRINTELLIX": 35.62027605040725, "CYMBALTA": 5.169757602813816, "VIAGRA": 15.048400772538647, "null": 4.2702599201505365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8579.json
index 4c009daf035..9bec13a929e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8579.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8579.json
@@ -1 +1 @@
-{"null": 1.4485318498946913}
\ No newline at end of file
+{"null": 6.019897882837011}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/858.json
index db6a0380712..19e93c64f0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/858.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/858.json
@@ -1 +1 @@
-{"COMIRNATY": 2.7804679281392986, "COVID19": 1.874206916867181, "PEGASYS": 1.4218323528373993, "PEGINTERFERON": 1.02810256266582, "PEGINTRON": 1.6339200681476034, "SHINGRIX": 6.537760825699066, "SPIKEVAX": 2.73625648598697, "STELARA": 1.809353168180268, "TOZINAMERAN": 9.50709717231816, "ZOSTAVAX": 7.838862436325953}
\ No newline at end of file
+{"ALENDRONATE": 884.2587082422037, "APIXABAN": 83.88287235472347, "AVANDIA": 10.39883154122372, "CLOPIDOGREL": 4.81689464087982, "COMIRNATY": 0.1347773926033675, "DULOXETINE": 12.792653790343785, "ELIQUIS": 6.472432424849324, "FORSTEO": 3.88821789437354, "SILDENAFIL": 18.67952779479054, "null": 0.6969786733105937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8580.json
index bfbebe3be11..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8580.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8580.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 2.6012099944001474, "AZATHIOPRINE": 1.0326666683021506, "CELLCEPT": 3.2599324921639803, "NIMENRIX": 1.26366074164777, "ROACTEMRA": 1.2013315901835084, "SHINGRIX": 2.381712401955125, "SIMPONI": 1.0810138175817596, "SYNAGIS": 2.6001533191040567, "ZOSTAVAX": 5.577965828526666, "null": 13.544004575954627}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8581.json
index 326a4cc1035..7d8bc3a826d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8581.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8581.json
@@ -1 +1 @@
-{"null": 44.486327721891634}
\ No newline at end of file
+{"ENTACAPONE": 258.7186522340258, "LATUDA": 41.06326569656673, "LEVODOPA": 128.2575176357359, "OLANZAPINE": 13.727973206769429, "null": 2.286719069974682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8582.json
index f771f620527..d79193e47ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8582.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8582.json
@@ -1 +1 @@
-{"null": 2.182707492679382}
\ No newline at end of file
+{"COMIRNATY": 0.4708352612368854, "SPIKEVAX": 0.678972353696954, "SUTENT": 1.7610190519007436, "TOZINAMERAN": 2.3824042491120787, "VAXZEVRIA": 0.8810085112333625, "null": 1.3140536699562757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8583.json
index e785e4bfee3..b41ba368e60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8583.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8583.json
@@ -1 +1 @@
-{"ZOSTAVAX": 57.61123800070495}
\ No newline at end of file
+{"null": 0.3700478415865874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8584.json
index a5f12824263..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8584.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8584.json
@@ -1 +1 @@
-{"CELLCEPT": 38.05272509512184, "ZOSTAVAX": 73.02133441692403}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8585.json
index 2372ed52f49..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8585.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8585.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 32.53639145212722, "BORTEZOMIB": 16.88964894513963, "BUSULFAN": 20.3689079644511, "CELLCEPT": 5.440751493405972, "CICLOSPORIN": 19.023282950213, "CYTARABINE": 6.7404349733585445, "DEXAMETHASONE": 3.2738665202140567, "MYCOPHENOLATE": 24.95384070104273, "RINVOQ": 9.929327595907507, "RITUXIMAB": 4.057886656531585, "SHINGRIX": 10.863486284427804, "TACROLIMUS": 22.159620992696937, "THALIDOMIDE": 25.852618001457504, "ZOSTAVAX": 11.32545490064734}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8586.json
index 9dc066a7f69..c5f32539e07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8586.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8586.json
@@ -1 +1 @@
-{"ADCIRCA": 21.885270361976197, "AVASTIN": 11.179811456468952, "CLOPIDOGREL": 2.119029957975615, "EFAVIRENZ": 13.704253364061334, "EMTRICITABINE": 22.74528012338434, "EPCLUSA": 27.045297843789857, "EPIVIR": 35.63120988309785, "HARVONI": 12.72467366239956, "INCIVO": 7.966398189541869, "JAKAVI": 11.494522491983023, "JANUMET": 4.941632104652662, "KALETRA": 12.152385530181544, "NEXAVAR": 6.068199854847933, "OCALIVA": 24.7514758920342, "OPSUMIT": 2.2180423716765003, "PEGASYS": 13.218864828360244, "PEGINTRON": 6.368217206785163, "RIBAVIRIN": 13.629255882454062}
\ No newline at end of file
+{"ACLIDINIUM": 342.6936893694759, "ATAZANAVIR": 25.99272725047675, "BUDESONIDE": 4.834444441531706, "COSENTYX": 9.959892852522918, "TRELEGY": 28.24853998070572, "null": 1.348571723689481}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8587.json
index 64b3e54eff0..947a3c8d888 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8587.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8587.json
@@ -1 +1 @@
-{"ABACAVIR": 16.96637215021089, "null": 2.5955461117514167}
\ No newline at end of file
+{"ABILIFY": 7.230771245720175, "ACLIDINIUM": 22.966397516323312, "AFINITOR": 0.4570897367159225, "APREPITANT": 10.805707007532696, "AVAMYS": 1.3427696680767511, "BUDESONIDE": 0.5970174429063935, "CHAMPIX": 0.5390496268953265, "COMIRNATY": 2.715682146067699, "COSENTYX": 0.7540084997892244, "DARZALEX": 2.3353420716768527, "DEXAMETHASONE": 0.61646794752767, "ELIQUIS": 0.2522098750357395, "ENBREL": 0.7588953126746855, "EXFORGE": 1.137853006597495, "FASENRA": 2.61706527089436, "FASLODEX": 1.3471760764093013, "FORSTEO": 0.516378330603852, "IBRANCE": 0.6115479217866031, "LEVOFLOXACIN": 0.4106099463356184, "MODERNA": 0.606586698436723, "NEXAVAR": 0.3336690911561823, "NUCALA": 1.1545589974020063, "OMALIZUMAB": 1.5789321367603897, "PANTOPRAZOLE": 3.133617912349637, "PEGASYS": 0.3293907427158573, "RELVAR": 10.198770429109883, "RINVOQ": 0.8991258025191535, "RIXATHON": 14.92179927166421, "SPIKEVAX": 0.9081800644818898, "SUTENT": 0.1610316165422745, "TOZINAMERAN": 1.6384899831702175, "TRELEGY": 3.7675063562238074, "VAXZEVRIA": 0.4653107589496782, "XELJANZ": 0.5026120254583043, "XOLAIR": 0.7585046316346973, "null": 1.284277934988311}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8588.json
index ff0e4662aa7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8588.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8588.json
@@ -1 +1 @@
-{"COMIRNATY": 2.27748777267244, "COVID19": 1.7626263155554454, "VAXZEVRIA": 5.845858536952953}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8589.json
index e3ec2eef7b6..54d66809e5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8589.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8589.json
@@ -1 +1 @@
-{"ENBREL": 22.3068399441898}
\ No newline at end of file
+{"COMIRNATY": 1.3304358960588494, "null": 1.3373563545352634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/859.json
index d0a1501ace3..f7be4ec590f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/859.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/859.json
@@ -1 +1 @@
-{"null": 2.0895536841468973}
\ No newline at end of file
+{"null": 2.7373792987157866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8590.json
index 3e884ee4a95..048bcdce1e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8590.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8590.json
@@ -1 +1 @@
-{"APIDRA": 1.8634748836331647, "BELIMUMAB": 90.30049662250867, "BENLYSTA": 3.792892174522168, "COMIRNATY": 1.4281174992473409, "COVID19": 1.3355394684996449, "CYMBALTA": 1.679562546719085, "ELIQUIS": 3.8188055604719646, "EVISTA": 11.731844006539845, "FORSTEO": 2.6850119467338605, "IBRANCE": 1.041224876051586, "INSULIN": 1.893727740985956, "JANUVIA": 1.7242838962347211, "NUCALA": 1.2394652702693083, "OFEV": 3.4721469064555444, "PEGINTRON": 1.231949365128881, "SIMPONI": 3.5660068925513744, "STELARA": 1.1203351365286298, "VAXZEVRIA": 2.522107753004946, "XELJANZ": 1.382874759296609, "ZOSTAVAX": 2.320067612114117}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8591.json
index dee41cbb58b..703949f081b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8591.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8591.json
@@ -1 +1 @@
-{"null": 1.5645262835561466}
\ No newline at end of file
+{"COMIRNATY": 0.2498764494953693, "SUTENT": 3.277121182050417, "null": 1.629973574880824}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8592.json
index 44befa60ae9..a69846ea5de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8592.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8592.json
@@ -1 +1 @@
-{"NEXAVAR": 64.65052143230412}
\ No newline at end of file
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8593.json
index 739d8e72c86..6d82528b878 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8593.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8593.json
@@ -1 +1 @@
-{"ABATACEPT": 18.852504922564123, "CYTARABINE": 39.89214261637929, "NAGLAZYME": 102.4493073928636, "RUCONEST": 874.2489271379047}
\ No newline at end of file
+{"null": 1.7466974471949457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8594.json
index b0db2a5b3dd..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8594.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8594.json
@@ -1 +1 @@
-{"RUCONEST": 13158.557593359932}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8595.json
index eab1267eb1e..be12499cec6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8595.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8595.json
@@ -1 +1 @@
-{"RUCONEST": 4122.597864893069}
\ No newline at end of file
+{"COMIRNATY": 0.4721773812268639, "SPIKEVAX": 0.3404013117056801, "VAXZEVRIA": 0.1717720541006759, "XOLAIR": 5.334275528398657, "null": 2.7795761627634006}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8596.json
index 32ca5dda61c..dc5b7154d7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8596.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8596.json
@@ -1 +1 @@
-{"null": 1.170753833896769}
\ No newline at end of file
+{"null": 2.5145325662297564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8597.json
index 886199c8d75..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8597.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8597.json
@@ -1 +1 @@
-{"null": 1.9021034470265756}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8598.json
index e2016b99d52..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8598.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8598.json
@@ -1 +1 @@
-{"ALISKIREN": 234.9042493389092}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8599.json
index e887d1b74eb..7891d5b06f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8599.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8599.json
@@ -1 +1 @@
-{"ELIQUIS": 42.25727010196169}
\ No newline at end of file
+{"KEPPRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/86.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/86.json
index b47276ecc20..6da6272b880 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/86.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/86.json
@@ -1 +1 @@
-{"null": 2.486041568829552}
\ No newline at end of file
+{"ADALIMUMAB": 0.8213966149120382, "AMIKACIN": 23.63360683482409, "CICLOSPORIN": 1.137835885182365, "CIMZIA": 1.9210677182564089, "COMIRNATY": 0.1735829335756675, "COSENTYX": 4.362661541755544, "ENBREL": 1.574648184961792, "FORXIGA": 3.7135787763418793, "HUMALOG": 2.4239262271517625, "JARDIANCE": 4.779649287594931, "LANTUS": 0.948556283687346, "METHOTREXATE": 2.2810323471018603, "NEXAVAR": 2.258015054011106, "PEGASYS": 3.1456478539677666, "PEGINTRON": 1.7202642512240935, "ROACTEMRA": 16.372372165500735, "SIMPONI": 6.581368394862498, "SOMATROPIN": 27.31409671249371, "SPIKEVAX": 0.1554241798569564, "STELARA": 1.894274921217861, "SUBOXONE": 2.8443402403582376, "SUTENT": 1.6808446609467922, "VAXZEVRIA": 0.1765612821736559, "XELJANZ": 2.5025968224010438, "ZOSTAVAX": 1.563834109432345, "ZYPADHERA": 8.907174373435073, "null": 0.7393604949627067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/860.json
index 8cdf6586f5e..dc472c856bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/860.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/860.json
@@ -1 +1 @@
-{"METHOTREXATE": 165.9414240888942}
\ No newline at end of file
+{"COMIRNATY": 0.2518734840035883, "DOCETAXEL": 15.008312570377834, "FILGRASTIM": 124.04884208021328, "HERCEPTIN": 19.790133136971345, "KEYTRUDA": 3.1344817389793667, "PEGFILGRASTIM": 613.5579472683735, "VAXZEVRIA": 0.112399270755346, "null": 2.391993115337421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8600.json
index 470b185b774..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8600.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8600.json
@@ -1 +1 @@
-{"LANTUS": 4.798684584508915, "ZYPREXA": 7.412748895653999}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8601.json
index 7d728ef8504..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8601.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8601.json
@@ -1 +1 @@
-{"ADCIRCA": 40.55112942673605, "ADEMPAS": 14.688126258422871, "ADVATE": 47.4278604348247, "ALEMTUZUMAB": 8.127834469277639, "AMBRISENTAN": 34.23346945907328, "AVASTIN": 3.489753644191182, "BEVACIZUMAB": 3.7105654893141375, "BORTEZOMIB": 20.45438759252028, "CINRYZE": 155.2045432124882, "DOCETAXEL": 4.413321136500792, "MACITENTAN": 70.31561265457778, "METHOTREXATE": 2.179155029112528, "OPSUMIT": 30.12499205922874, "REVESTIVE": 110.71144344430743, "RUCONEST": 48.001159839670464, "SOLIRIS": 6.553491076826704, "TRACLEER": 28.89979877487792, "null": 1.9065387936005924}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8602.json
index e4f75ad1dfd..2a61a3b1f1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8602.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8602.json
@@ -1 +1 @@
-{"null": 1.7792985309282547}
\ No newline at end of file
+{"null": 1.1233287695500775}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8603.json
index 8838c52a92e..14146a7b245 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8603.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8603.json
@@ -1 +1 @@
-{"BEDAQUILINE": 117.62320384450376}
\ No newline at end of file
+{"AFINITOR": 2.810178921938966, "APIXABAN": 4.718253950361012, "AVANDIA": 11.616204282460613, "BRILIQUE": 8.993105681500293, "BUDESONIDE": 1.155796239522502, "CLOPIDOGREL": 5.540523635352439, "COMIRNATY": 0.4195440486101952, "ENTRESTO": 22.99954149103805, "EXJADE": 2.42879212732862, "MIDAZOLAM": 5.371866614092294, "NUCALA": 2.151616178639977, "OPSUMIT": 6.689288859094457, "PLAVIX": 1.4824158852605815, "SPIKEVAX": 0.2424743499153983, "TOZINAMERAN": 0.3194746016080403, "TRACLEER": 8.420093556048611, "VALSARTAN": 11.50886381992278, "VAXZEVRIA": 0.1293932609938944, "VOTRIENT": 3.537026681557241, "null": 1.2905215078948364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8604.json
index b30067775d0..a70aa16883b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8604.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8604.json
@@ -1 +1 @@
-{"AVANDIA": 48.133238740483016, "ELIQUIS": 1.4714778393368726, "HUMALOG": 4.523296790439978, "JANUMET": 6.453306694806062, "JARDIANCE": 11.26711554463185, "LANTUS": 16.099129662206444, "PLAVIX": 6.808008210158391, "XTANDI": 4.104576591490448}
\ No newline at end of file
+{"KESIMPTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8605.json
index bd692d924e0..c0b9e159ebf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8605.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8605.json
@@ -1 +1 @@
-{"null": 1.354349297204551}
\ No newline at end of file
+{"null": 4.494631436120529}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8606.json
index 4116c716101..680d014a25b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8606.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8606.json
@@ -1 +1 @@
-{"COVID19": 12.218704716301591, "TOZINAMERAN": 2.4554467342957302}
\ No newline at end of file
+{"ABILIFY": 111.30641883025262, "ARIPIPRAZOLE": 19.914827209529804, "null": 0.7950383023920826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8607.json
index 4fd54949f29..ed306144a3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8607.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8607.json
@@ -1 +1 @@
-{"ARAVA": 1.0425265032251194, "CLOPIDOGREL": 5.880760708752113, "VAXZEVRIA": 1.141620777816931, "null": 1.1945095392048617}
\ No newline at end of file
+{"ABILIFY": 1.1589573554626134, "AMBROXOL": 119.58256281472892, "AMLODIPINE": 100.3585679176368, "APIXABAN": 0.257259430530497, "APROVEL": 18.56403432181273, "ARIPIPRAZOLE": 5.215761112477222, "AZILECT": 15.48750813100114, "BOTULINUM": 2.265449618361581, "BRILIQUE": 1.030342675422644, "BRIMICA": 143.70243588949037, "BRINTELLIX": 0.8516315798407359, "BUDESONIDE": 0.1899477548653905, "BUMETANIDE": 6.817794498221135, "BUPRENORPHINE": 1.1394521313324977, "BYETTA": 0.3658436086435334, "CAFFEINE": 72.16789959699128, "CARBIDOPA": 4.551461487331177, "CARIPRAZINE": 20.968827555269566, "CHAMPIX": 0.3126200849567027, "CIMZIA": 0.1851032889169714, "CLOPIDOGREL": 1.1781756992766157, "COAPROVEL": 17.138505777500352, "COMIRNATY": 0.1346281211868167, "COSENTYX": 0.4105643171872061, "CRIZOTINIB": 26.94366211128266, "CYMBALTA": 2.7946640346117606, "DARZALEX": 0.9948934938708488, "DEXAMETHASONE": 1.2329528078054426, "DULOXETINE": 1.34856222735402, "EBIXA": 9.311996044944376, "ELIQUIS": 0.4895824588439335, "ENTACAPONE": 8.656847917878409, "ENTRESTO": 6.105902987583311, "EXELON": 7.952241610648849, "EXFORGE": 2.9325765279722686, "FENTANYL": 0.38469119936478, "FIRDAPSE": 1.578018704371545, "FORSTEO": 0.7079139975640879, "FORXIGA": 0.9160207652126722, "GARDASIL": 1.5285623193961153, "HUMALOG": 0.3781712399612877, "IBRANCE": 0.2536916069790474, "IRBESARTAN": 11.571607192751546, "JARDIANCE": 1.0900068573832271, "KARVEA": 9.62539460574667, "KEPPRA": 0.6637722474671759, "KEYTRUDA": 0.1207560993674182, "LANTUS": 0.356636949853331, "LEVODOPA": 8.588162036144631, "LEVOFLOXACIN": 38.07349086938439, "LYRICA": 0.7385877513969511, "METHOTREXATE": 0.758665848739386, "MICARDIS": 7.421186332731648, "MICARDISPLUS": 14.459104903511028, "OLANZAPINE": 2.932537320826188, "OPSUMIT": 0.2921591409547256, "OPTIMARK": 0.5135731423348535, "PANTOPRAZOLE": 0.8074595349715273, "PEGASYS": 0.0959292082282247, "PEGINTERFERON": 0.5191382409346275, "PEGINTRON": 0.2034677000671096, "PLAVIX": 0.4251602364271141, "PREGABALIN": 1.4927373578494123, "PRITORPLUS": 80.76180426002009, "PROPRANOLOL": 4.9672540699881065, "RANEXA": 6.360893294511393, "RANOLAZINE": 6.474868068459282, "RASILEZ": 2.4040955218865854, "RISPERIDONE": 2.43833833783586, "SAXENDA": 0.5637650443347446, "SIFROL": 5.725709897526539, "SILODOSIN": 29.58962732444576, "SILODYX": 25.10893854031771, "SPIKEVAX": 0.0909260766215321, "SPIRONOLACTONE": 11.740996879867712, "STALEVO": 6.362135201932418, "SUTENT": 0.1770040163693304, "TAMIFLU": 0.5624253742897324, "TELMISARTAN": 7.026435944865429, "THALIDOMIDE": 3.313278862760212, "TOVIAZ": 0.9071938286883756, "TOZINAMERAN": 0.3157171780193156, "UROREC": 29.55055470880943, "VALSARTAN": 2.396163855438834, "VAXZEVRIA": 0.0955014530598066, "VELCADE": 7.052992751770212, "XOLAIR": 0.2085154827421245, "XTANDI": 0.4425245744952304, "YESCARTA": 1.1679615259247924, "ZOSTAVAX": 0.3333418173407942, "ZYPADHERA": 1.4950068719647256, "ZYPREXA": 2.268282567812237, "null": 2.6344061840304405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8608.json
index 02089bc3053..9906d87bac4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8608.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8608.json
@@ -1 +1 @@
-{"null": 1.258782204035324}
\ No newline at end of file
+{"COMIRNATY": 1.4272731637816225, "GARDASIL": 108.22267915678968, "SPIKEVAX": 0.5874280074447438, "TOZINAMERAN": 0.4937960419471163, "VAXZEVRIA": 0.2674906094217373, "null": 0.4122710413642731}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8609.json
index 74eacfc8aec..446c817514a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8609.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8609.json
@@ -1 +1 @@
-{"AIMOVIG": 255.05513456673583, "BOTULINUM": 140.1788960645248, "GARDASIL": 11.40501691928078}
\ No newline at end of file
+{"null": 0.9536240008229327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/861.json
index ba923b22d47..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/861.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/861.json
@@ -1 +1 @@
-{"null": 2.023146762353026}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8610.json
index 8851d1d051a..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8610.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8610.json
@@ -1 +1 @@
-{"OLANZAPINE": 111.0995887837676}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8611.json
index 6caa5835a81..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8611.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8611.json
@@ -1 +1 @@
-{"AVANDIA": 2.842262095458905, "ELIQUIS": 2.5828577298352, "HUMALOG": 8.354291217511173, "ICLUSIG": 12.789059565982903, "LANTUS": 5.3724549000572965, "PLAVIX": 17.49389637437199, "TASIGNA": 7.11349297118067, "TOPOTECAN": 44.88639736293338, "null": 1.1786055559415456}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8612.json
index 97827aa5538..22b6c25c5e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8612.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8612.json
@@ -1 +1 @@
-{"ADCETRIS": 40.88787656818098, "COMIRNATY": 2.1339417027539027, "COVID19": 2.788624026274165, "ORENCIA": 54.5145175641762, "SPIKEVAX": 1.1973900173865033, "TOZINAMERAN": 1.7433849194102968, "VAXZEVRIA": 3.003513148479913}
\ No newline at end of file
+{"null": 1.3739080340530254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8613.json
index a5b04716431..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8613.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8613.json
@@ -1 +1 @@
-{"APIXABAN": 5.146011090566589, "CLOPIDOGREL": 29.24821033602416, "EFIENT": 64.32503891901919, "ELIQUIS": 3.310441291262918, "PLAVIX": 20.764356914504603, "null": 1.3231473674237355}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8614.json
index 246a06fd25c..059e40c7aec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8614.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8614.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 37.91017685665359, "null": 1.0143544196383385}
\ No newline at end of file
+{"null": 4.8401644167385305}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8615.json
index 6494fc3ca56..b5ba1a5e2e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8615.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8615.json
@@ -1 +1 @@
-{"COSENTYX": 1.973672710231428, "ELIQUIS": 3.423264069837594, "NOVONORM": 32.95197618923166, "PLAVIX": 1.8945894369875584, "null": 3.8833284020138654}
\ No newline at end of file
+{"CICLOSPORIN": 12.124639598172283, "PEGASYS": 7.2797245048246015, "null": 3.1354495102148947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8616.json
index 8fa695fa491..1d706492718 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8616.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8616.json
@@ -1 +1 @@
-{"RIOCIGUAT": 79946.97217693867}
\ No newline at end of file
+{"PIRFENIDONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8617.json
index 18f780cc70c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8617.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8617.json
@@ -1 +1 @@
-{"null": 1.7665232745441233}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8618.json
index 585d94710ad..7d638aa5ed0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8618.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8618.json
@@ -1 +1 @@
-{"null": 4.793129411962667}
\ No newline at end of file
+{"ACLASTA": 83.46835268608572, "ARAVA": 0.571766683146087, "BONVIVA": 53.53767787315208, "CELLCEPT": 6.048135657241917, "COMIRNATY": 0.8597582608557186, "FORSTEO": 5.9543516813421, "NEXAVAR": 4.8747877273999, "OCRELIZUMAB": 14.060918278305577, "ROACTEMRA": 12.128035476440212, "SIMPONI": 5.137381987516688, "SPIKEVAX": 0.4821273520663587, "STELARA": 4.849497927164819, "SUTENT": 1.1977013290360428, "VAXZEVRIA": 0.2991209119353205, "XELJANZ": 2.3808028403306034, "null": 0.4207246298927588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8619.json
index 492aa0e9270..439c968904e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8619.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8619.json
@@ -1 +1 @@
-{"ELIQUIS": 3.6853321938930974, "VAXZEVRIA": 1.2423462738833362, "VIAGRA": 10.729412250067451}
\ No newline at end of file
+{"DOCETAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/862.json
index 6d1a2432522..a9721816b5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/862.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/862.json
@@ -1 +1 @@
-{"null": 5.198964971256344}
\ No newline at end of file
+{"AZACITIDINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8620.json
index d94795564eb..5e306b76e2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8620.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8620.json
@@ -1 +1 @@
-{"TASIGNA": 38.024486356969085}
\ No newline at end of file
+{"FORSTEO": 28.586770555592462, "null": 0.8456819401039402}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8621.json
index cb2ecd6a490..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8621.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8621.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 13.335926128647149, "PLAVIX": 54.43452760316192, "null": 2.599098033268341}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8622.json
index 1595949a581..03b18175877 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8622.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8622.json
@@ -1 +1 @@
-{"BRILIQUE": 82.11066654946829, "CLOPIDOGREL": 30.14483793828569, "EFIENT": 346.81937805228574, "INSULIN": 19.344187943222632, "PLAVIX": 29.256617857753945, "null": 1.1757203328706507}
\ No newline at end of file
+{"ABASAGLAR": 1.5006361622624202, "ABATACEPT": 6.137642016500419, "ABILIFY": 0.537523025960606, "ACLASTA": 8.714316233681705, "ADALIMUMAB": 3.172191646082732, "AFINITOR": 0.5352362658027827, "AIMOVIG": 0.4072223045970546, "AMINOSALICYLIC": 1.556764449641496, "ANAKINRA": 1.2196354962939853, "APIDRA": 1.213255963438115, "APIXABAN": 0.6499366158712664, "APREMILAST": 2.873053991334549, "APROVEL": 1.2624071834083628, "ARAVA": 4.000919396590983, "ATRIPLA": 7.662553839518045, "AUBAGIO": 0.4201718601679534, "AVONEX": 5.046791503063728, "AZATHIOPRINE": 0.7898520801222119, "BENLYSTA": 0.7853497549703948, "BIKTARVY": 0.58045134693295, "BONVIVA": 1.9503601701733309, "BUDESONIDE": 0.5960982227081495, "BUPRENORPHINE": 0.3689781772174888, "BYDUREON": 0.8355820633488585, "BYETTA": 2.7011947326082164, "CANNABIDIOL": 6.11201945184307, "CELECOXIB": 4.341118862648496, "CHAMPIX": 0.1746188420973832, "CICLOSPORIN": 0.2381121436485792, "CIMZIA": 1.5345235415676957, "CLOPIDOGREL": 0.4412495368236255, "COMIRNATY": 0.2873485950361083, "COSENTYX": 4.135767139459426, "CRIXIVAN": 3.286303745960675, "CYMBALTA": 2.5547997346865787, "DEXAMETHASONE": 0.2873944025992694, "DULOXETINE": 3.014604740611936, "ELIQUIS": 1.3639305285967174, "EMPAGLIFLOZIN": 2.3215074124233177, "ENBREL": 5.3629243042662935, "ENTRESTO": 0.3233442035351324, "ENTYVIO": 0.3792311989469931, "ERELZI": 8.6585228748076, "ESBRIET": 0.4133061648404046, "EVENITY": 1.6190606987034704, "EVISTA": 2.7333487465784008, "EXFORGE": 2.157010251250268, "EXJADE": 0.2864760759260845, "FAMPYRA": 1.644325329006914, "FASENRA": 0.9984298488019068, "FASLODEX": 1.0041961770206012, "FIRDAPSE": 1.4189665195007055, "FORSTEO": 3.5436182546070243, "GALVUS": 2.869443626100271, "GARDASIL": 0.2302539421445267, "HUMALOG": 1.1941665564488362, "HUMIRA": 6.089591043749673, "HYDROCORTISONE": 1.7180772015671717, "IBRANCE": 1.0828582159581426, "IBUPROFEN": 0.365040886679659, "INSULIN": 0.7703575842050375, "ISENTRESS": 1.0893355923183292, "JAKAVI": 0.4501271673110272, "JANUMET": 4.7291838768633, "JANUVIA": 3.746527455364527, "JARDIANCE": 0.2350728658336597, "KEPPRA": 0.5516476259644002, "KEYTRUDA": 0.2904878376969841, "KISQALI": 1.1290530809237207, "KIVEXA": 4.465408946100279, "LANTUS": 1.0233140014025928, "LEFLUNOMIDE": 7.806537734127797, "LEVEMIR": 0.6549103694073294, "LEVOFLOXACIN": 0.6889572423413026, "LYRICA": 1.4052142222823691, "METHOTREXATE": 7.778314653009637, "MICARDIS": 0.971498374194837, "NUCALA": 0.4404764144576943, "OMALIZUMAB": 0.5586654451504319, "OPTIMARK": 1.2222704839540914, "ORENCIA": 10.960790873486228, "PANTOPRAZOLE": 2.0624669237222104, "PEGASYS": 0.1534802799360049, "PEGINTRON": 0.2632348218868522, "PLAVIX": 0.4561710429138398, "PROLIA": 5.216499118007124, "RASILEZ": 1.3010894862587328, "REMICADE": 1.5676790648026475, "RINVOQ": 2.76009506262012, "RITUXIMAB": 0.7265638250271776, "ROACTEMRA": 0.6459197095618341, "SHINGRIX": 0.7865646427189917, "SIMPONI": 2.916287537347727, "SPIKEVAX": 0.1726180939898485, "STELARA": 0.7341712082467111, "STRIBILD": 4.125715809934811, "SUBOXONE": 0.3926659451796471, "SUTENT": 0.2866207623094264, "TASIGNA": 0.8800391600175677, "TOVIAZ": 0.9926670330256736, "TOZINAMERAN": 0.3329522082595698, "TRULICITY": 0.450835871253201, "TRUVADA": 4.618559494639511, "VAXZEVRIA": 0.1677765198384103, "VIAGRA": 0.8125255844753296, "VIREAD": 2.467252235641249, "XELJANZ": 6.0892012879426645, "XOLAIR": 0.4022157852108935, "XYREM": 1.361680769786647, "ZOSTAVAX": 8.997930805431825, "ZYPREXA": 0.2548595251999193, "null": 0.6126286607933976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8623.json
index 52cd61f85e3..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8623.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8623.json
@@ -1 +1 @@
-{"ANGIOX": 89.51621675808734, "BRILIQUE": 158.4461983929955, "CLOPIDOGREL": 49.49765835537662, "EFIENT": 98.72190656238784, "INTEGRILIN": 27.102178320942453, "PLAVIX": 34.474044570863825, "TICAGRELOR": 30.77366095198895, "ZYLLT": 138.0150982923855, "null": 1.8523898982238325}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8624.json
index d7fb1a83965..762b2252d72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8624.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8624.json
@@ -1 +1 @@
-{"TAMIFLU": 18.249286522458576, "TOZINAMERAN": 1.0154088096921228}
\ No newline at end of file
+{"null": 2.4396486689105443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8625.json
index b745d7e2638..2b96d5ac351 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8625.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8625.json
@@ -1 +1 @@
-{"AERIUS": 5.043565772697956, "ALIMTA": 1.300283014411462, "ANORO": 4.830825194396986, "APIXABAN": 2.630909178957729, "APROVEL": 3.717784236531808, "AZATHIOPRINE": 10.690232438254762, "BENLYSTA": 2.3096904202581925, "BEOVU": 8.92847517185919, "BETAFERON": 1.7958958618818737, "BUDESONIDE": 11.923071748185828, "CELECOXIB": 20.17738209697164, "CELLCEPT": 1.4420064393914929, "CIMZIA": 1.3460535728902985, "COSENTYX": 1.28090691339345, "DEXAMETHASONE": 1.5755718292287246, "ELIQUIS": 1.1125366298157142, "ENTYVIO": 1.7021656107644547, "ETANERCEPT": 6.094589287386944, "FASENRA": 1.9459920552560213, "FILGRASTIM": 2.6227559250273336, "GARDASIL": 1.0590851602915623, "HUMAN": 1.837923874320116, "INCIVO": 1.385122808998038, "IPILIMUMAB": 2.4205366342644146, "KALETRA": 1.475552947846809, "KEYTRUDA": 1.0856669556578369, "LEVOFLOXACIN": 1.2195038154285678, "NEULASTA": 1.2127950121393425, "NUCALA": 13.480226469708178, "PEGASYS": 1.6672668799380257, "PEGFILGRASTIM": 10.577852194339638, "PEGINTERFERON": 1.6991951584935112, "PEGINTRON": 2.1351152580651007, "PEMBROLIZUMAB": 2.9312153737948616, "REMICADE": 2.7525228280663736, "RITUXIMAB": 1.3137201325937955, "ROACTEMRA": 4.062132377885773, "SIMPONI": 2.288891015870034, "STELARA": 1.964662854300354, "TAGRISSO": 1.3446464530095008, "TAMIFLU": 1.017726165282324, "TOCILIZUMAB": 5.825689795595157, "TREMFYA": 1.2124851022050072, "TWINRIX": 2.7126668606465723, "XOLAIR": 1.7375330796083737, "null": 1.2100054895771948}
\ No newline at end of file
+{"null": 1.4001987331027643}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8626.json
index 98c916d2c38..ad0cf314a5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8626.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8626.json
@@ -1 +1 @@
-{"null": 2.2058289165384624}
\ No newline at end of file
+{"null": 1.0779278232542049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8627.json
index 01847ecdacd..59b05b77cd3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8627.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8627.json
@@ -1 +1 @@
-{"null": 2.431575004969513}
\ No newline at end of file
+{"ABACAVIR": 7.523871228005273, "ADENURIC": 71.49008165803845, "ATRIPLA": 2.570138085112598, "COMIRNATY": 0.6784724938835748, "STRIBILD": 9.733075617096606, "TRUVADA": 2.885117636957224, "null": 0.864759847661994}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8628.json
index 8bdd36e02c2..90107168b78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8628.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8628.json
@@ -1 +1 @@
-{"null": 3.4671505055448164}
\ No newline at end of file
+{"ATRIPLA": 2.58545097622199, "KALETRA": 42.53115559064525, "null": 0.8552265968089774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8629.json
index caf211c1694..1a4ebf6d74f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8629.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8629.json
@@ -1 +1 @@
-{"ABACAVIR": 1.8580107506762091, "AVANDIA": 1.2730397651988326, "COMIRNATY": 1.1641952941131295, "COVID19": 1.6984333007886403, "OPSUMIT": 1.909707409144117, "VAXZEVRIA": 3.0064311789355886, "null": 1.0951882637578936}
\ No newline at end of file
+{"ADENURIC": 49.32639738163517, "ARAVA": 5.403191692552197, "CAPECITABINE": 16.10761687216456, "CARFILZOMIB": 78.96488043202325, "CICLOSPORIN": 5.799061924293516, "FULVESTRANT": 16.75248395665225, "NEXAVAR": 5.407297025091355, "null": 0.4145525150388681}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/863.json
index 017fd43b6bd..cd4d0a80bc4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/863.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/863.json
@@ -1 +1 @@
-{"OLANZAPINE": 268.9572815303201}
\ No newline at end of file
+{"APIXABAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8630.json
index bdf924dc294..ab411234d3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8630.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8630.json
@@ -1 +1 @@
-{"null": 2.0563873272694297}
\ No newline at end of file
+{"ADENURIC": 508.6663422108844, "null": 0.6180072909783187}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8631.json
index 1c149d3672d..83a6f74b724 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8631.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8631.json
@@ -1 +1 @@
-{"CICLOSPORIN": 9.412007363956626, "XALKORI": 64.93326519523193}
\ No newline at end of file
+{"ATRIPLA": 34.36806163286362, "ENTECAVIR": 48.0659823795009, "HEPSERA": 645.4999120606287, "KALETRA": 4.4157868983085145, "LOPINAVIR": 18.693486370555608, "STRIBILD": 15.30060678883252, "TENOFOVIR": 99.17814845409876, "TRUVADA": 27.71823713318533, "VIREAD": 68.067425460411, "null": 0.1712983951639282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8632.json
index 7dbfa7832ea..099a545d79a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8632.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8632.json
@@ -1 +1 @@
-{"METHOTREXATE": 78.17223334159516}
\ No newline at end of file
+{"ACLASTA": 17.399752673986765, "ADALIMUMAB": 0.7254350173202881, "AFINITOR": 1.2310869209883029, "ARAVA": 0.531939281408734, "ATRIPLA": 1.6636434335022845, "AUBAGIO": 1.3980957596050363, "AVANDIA": 0.8181440839740528, "BENLYSTA": 2.4460211871849213, "BONVIVA": 44.95133363244908, "BUPRENORPHINE": 1.7664710588777046, "CABOMETYX": 1.8733315365290195, "CELECOXIB": 10.537403215361934, "CELLCEPT": 2.468056173114741, "CICLOSPORIN": 1.8297680274603083, "CIMZIA": 1.7116772309959272, "CLOPIDOGREL": 0.5975878522122463, "COMIRNATY": 0.0405490062048565, "COSENTYX": 1.4598729828349952, "CUBICIN": 21.84415709602437, "CYMBALTA": 1.126965245325236, "CYTARABINE": 1.2319639077559383, "DASATINIB": 11.691476398155068, "DEXAMETHASONE": 2.2490180708488383, "ELIQUIS": 0.6276263106625616, "ENBREL": 2.2705991635854263, "ENTYVIO": 1.1132891644639944, "EVENITY": 5.840069245667778, "EXJADE": 0.9524007522415484, "FASLODEX": 1.6380535003315504, "FORSTEO": 0.9744768982832632, "FORXIGA": 1.1601706018760054, "HIZENTRA": 3.66101846564404, "HUMALOG": 6.0637094495783765, "IBRANCE": 2.64645434049071, "INLYTA": 1.9188432856807296, "INSULIN": 2.7150477794562, "INVOKANA": 148.59832760374488, "JANUMET": 1.531640043186705, "JARDIANCE": 4.389213248561052, "JEVTANA": 5.034794245238509, "KEYTRUDA": 0.6813494150005093, "LANTUS": 3.1300887689700474, "LEVEMIR": 2.37644188856569, "LEVOFLOXACIN": 0.8065186068752824, "LYRICA": 1.7067555203788782, "METHOTREXATE": 2.572419019845675, "MYCOPHENOLATE": 2.723360144273229, "OPTIMARK": 3.578151098040038, "PEGASYS": 1.2802227138076987, "RINVOQ": 1.766069725287204, "ROACTEMRA": 6.098069167722163, "SIMPONI": 5.515745175652604, "SOLIRIS": 1.6436625821290962, "SPIKEVAX": 0.0510655851115689, "STELARA": 2.2459503486439925, "STRIBILD": 0.8990821592617578, "SUBOXONE": 1.005416104887849, "SUTENT": 0.7719498167744479, "TOZINAMERAN": 0.1399558335884013, "TRUVADA": 1.257958639632978, "VFEND": 1.4649248889540558, "XELJANZ": 4.740734318208935, "XOLAIR": 1.0163817996319788, "XTANDI": 0.8218955583496939, "ZOMETA": 35.10675871764828, "null": 0.6916404053204388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8633.json
index 1794c4308b5..3b5a95d92ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8633.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8633.json
@@ -1 +1 @@
-{"ENTRESTO": 8.429467771479342, "FENTANYL": 5.809267835119951, "GLUCAGON": 430.11637551698135, "null": 3.1979124410438864}
\ No newline at end of file
+{"INVOKANA": 466.94296709079504, "null": 0.517280068315317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8634.json
index ff67f72726f..c919d1942fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8634.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8634.json
@@ -1 +1 @@
-{"DASATINIB": 73.74022813608545, "null": 2.9213072083710547}
\ No newline at end of file
+{"null": 0.2198236407919148}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8635.json
index 19b60abe81c..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8635.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8635.json
@@ -1 +1 @@
-{"FENTANYL": 19.32095491643746}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8636.json
index 4c8c6286c84..9bb26c4736f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8636.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8636.json
@@ -1 +1 @@
-{"TOZINAMERAN": 1.3470885728590558, "VAXZEVRIA": 1.2258272793719207, "null": 1.6660636352874485}
\ No newline at end of file
+{"ABACAVIR": 0.4474630751127617, "ADALIMUMAB": 0.0111474585001064, "AFINITOR": 0.1146420840785886, "AMINOSALICYLIC": 0.1249894280685369, "ARAVA": 0.01841519478319, "ASPARAGINASE": 1.4531348214947697, "ATAZANAVIR": 0.9441670406923276, "ATRIPLA": 53.32455384026002, "AZATHIOPRINE": 0.6131849327777212, "BENLYSTA": 0.1275013344205821, "BIKTARVY": 1.59103135564877, "BONVIVA": 4.964407359658485, "BUDESONIDE": 0.1122694345708146, "BUSULFAN": 0.2624716952665659, "CELLCEPT": 0.3929446884218366, "CICLOSPORIN": 0.2920491196150683, "CIMZIA": 0.0353154507046373, "COAPROVEL": 0.2796552802663812, "COMBIVIR": 0.9843821270174244, "COMIRNATY": 0.0045468969195896, "COSENTYX": 0.0593327449203432, "CRIXIVAN": 2.5995832428780936, "CYMBALTA": 0.0282861852729463, "CYTARABINE": 1.3508517399411475, "DEXAMETHASONE": 0.445738165732305, "EFAVIRENZ": 1.274630317693099, "EMTRICITABINE": 1.1768909273082049, "EMTRIVA": 2.189586290976137, "ENBREL": 0.1304591469545929, "ENTYVIO": 0.1225634407695489, "EPIVIR": 2.667810004557924, "EVENITY": 0.4287562111263864, "EVISTA": 0.4367385847720064, "EXJADE": 0.0827597566412283, "FORSTEO": 0.2480568337614296, "GENVOYA": 3.2009706595492253, "HEPSERA": 0.7068254272155147, "HYDROCORTISONE": 0.5745484239893159, "IBRANCE": 0.0681289200886175, "INDINAVIR": 2.0354347674550377, "INVIRASE": 3.397353505165784, "ISENTRESS": 2.118328262212609, "JAKAVI": 0.4637967266767, "JARDIANCE": 0.0851534597090754, "KALETRA": 10.440076520182428, "KEPPRA": 0.0477822583350855, "KEYTRUDA": 0.047131683492233, "KIVEXA": 1.9886344521846984, "LAMIVUDINE": 0.5468858317429643, "LOPINAVIR": 2.048832851484157, "METHOTREXATE": 0.1305745585695765, "NEXAVAR": 0.1277308822383536, "NORVIR": 2.3158143652694068, "NPLATE": 0.1828478474787463, "OCEAN": 11.797922540172449, "OMALIZUMAB": 0.1121666122919322, "PEGASYS": 0.1833845706573754, "PEGINTRON": 0.0417257025495086, "RAPAMUNE": 0.4698199632896245, "REYATAZ": 3.5002651700339324, "RINVOQ": 0.25536483576478, "RITONAVIR": 2.06848121012976, "ROACTEMRA": 0.1577925105034893, "SIMPONI": 0.09986944024134, "SOLIRIS": 0.1764027789713584, "SOMATROPIN": 0.9394683402768186, "SPRYCEL": 0.1200132438713697, "STELARA": 0.1645179770313683, "STRIBILD": 40.16079280889993, "SUBOXONE": 0.1046212993255783, "SUTENT": 0.1428532234670884, "TASIGNA": 0.1264405777806901, "TENOFOVIR": 1.072512863071379, "TESTOSTERONE": 3.183937228998872, "THALIDOMIDE": 0.9509187424973714, "TIVICAY": 0.6402261133559407, "TRUVADA": 60.90031088752984, "VAXZEVRIA": 0.0026207014642732, "VIREAD": 15.360986277732517, "VOTRIENT": 0.1137975985690773, "XELJANZ": 0.1124811813929007, "XOLAIR": 0.0484179646995069, "ZOMETA": 5.591603834989503, "null": 0.0630506308458124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8637.json
index f66de0b168c..761a48f6a96 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8637.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8637.json
@@ -1 +1 @@
-{"BELIMUMAB": 142.91539099639402, "BENLYSTA": 6.861985047229591, "ELIQUIS": 2.595433906201764, "ENBREL": 6.701074541120087, "ENTRESTO": 2.562815872808366, "EXFORGE": 4.123850184264754, "FORSTEO": 2.094989132521753, "HUMALOG": 2.242360424173966, "IBRANCE": 2.638955868582172, "ILARIS": 307.9689277842574, "LANTUS": 1.4666985209535528, "TOZINAMERAN": 1.8026047283110584, "VIAGRA": 7.525102830157734, "XELJANZ": 1.522963398767362, "null": 1.0260212109999884}
\ No newline at end of file
+{"ACLASTA": 48.64531299490949, "ACLIDINIUM": 17.730997735917917, "AFINITOR": 13.298953544969752, "ALIMTA": 3.544968527356245, "ARAVA": 0.1196106968977417, "ATRIPLA": 0.1742964783798669, "AVASTIN": 5.592769820614654, "AXITINIB": 10.439589123311832, "BEVACIZUMAB": 4.923355213951762, "BONDRONAT": 458.2330193518784, "BONVIVA": 500.44137319738974, "BORTEZOMIB": 6.0937859417738895, "CABAZITAXEL": 16.99161096425291, "CABOMETYX": 22.01998092004542, "CAPECITABINE": 4.156931506701365, "DARZALEX": 6.340162451585181, "DENOSUMAB": 67.39420292653622, "DEXAMETHASONE": 3.839265299132927, "DOCETAXEL": 3.95164622060144, "EVENITY": 79.22637126581128, "EVISTA": 9.76611508895758, "FASLODEX": 5.799410801779114, "FORSTEO": 2.78173828062088, "FOSAVANCE": 240.23676751424856, "FULVESTRANT": 10.94710654114688, "IBRANCE": 8.662222131107415, "INLYTA": 3.691279153893254, "JEVTANA": 12.055093389380763, "KEYTRUDA": 0.6097627995514504, "LENVIMA": 7.223543500335463, "NEXAVAR": 2.549461265328836, "PEMETREXED": 4.687289583030724, "PROLIA": 24.149922892268723, "SORAFENIB": 14.70981260897226, "SUNITINIB": 86.25154931662397, "SUTENT": 12.096488930299095, "THALIDOMIDE": 12.31537943769507, "VOTRIENT": 2.294451649629253, "XGEVA": 189.02555822628665, "XOFIGO": 41.58192692163472, "XTANDI": 1.7516935568683112, "ZOLEDRONIC": 390.7119213060007, "ZOMETA": 194.4531119845519, "null": 0.3736205883183939}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8638.json
index 7e12496ef60..a8ef248e6f2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8638.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8638.json
@@ -1 +1 @@
-{"BENLYSTA": 12.766272162204825, "ELIQUIS": 4.854529351873127, "IBRANCE": 8.878906713193357, "RUCONEST": 80.15516947555281, "VAXZEVRIA": 1.1351011336278736, "XELJANZ": 3.354917183704217}
\ No newline at end of file
+{"ABACAVIR": 0.1619452483778781, "ABATACEPT": 0.4235068895972755, "ACLASTA": 6.537883717501369, "ADALIMUMAB": 0.0270913561907901, "ARAVA": 0.3151550192411796, "ATRIPLA": 68.30928615663177, "BIKTARVY": 0.7427157292495663, "BUDESONIDE": 0.2887778751508081, "BUPRENORPHINE": 0.3152195755702928, "BYETTA": 0.5256954035128376, "CICLOSPORIN": 0.1793850276311365, "COMIRNATY": 0.0048587992232189, "COSENTYX": 0.4967316846929456, "CYTARABINE": 0.2881426841765964, "DESCOVY": 2.8386089925677567, "EFAVIRENZ": 2.1395532168954507, "EMTRICITABINE": 4.308766513322853, "ENBREL": 0.8121028040763612, "EVEROLIMUS": 1.4905730651446891, "EVISTA": 0.5825066584051252, "FASLODEX": 0.7726440552876142, "HUMIRA": 0.2172199145955023, "IBRANCE": 0.4042402582743685, "ISENTRESS": 1.612920426344478, "JANUMET": 0.2963343811404151, "KALETRA": 3.6224422832624943, "KEPPRA": 0.1626282543853054, "LOPINAVIR": 2.5937450672109112, "METHOTREXATE": 0.2530567879149371, "NORVIR": 1.119849155520688, "OMALIZUMAB": 0.611781442770349, "OPTIMARK": 0.5155582919267527, "PEGASYS": 0.0605612135173839, "PEGINTRON": 0.1704755997965546, "STRIBILD": 31.278487027827527, "TENOFOVIR": 5.189291991228509, "TIVICAY": 3.734166142319564, "TOZINAMERAN": 0.0150247431790734, "TRUVADA": 39.595588742731046, "VIREAD": 22.847655999828397, "XELJANZ": 0.1857548458780758, "ZOSTAVAX": 2.1853976739061736, "null": 0.1186243698204727}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8639.json
index cfd3351586f..059b66004da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8639.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8639.json
@@ -1 +1 @@
-{"null": 4.147715741662421}
\ No newline at end of file
+{"ABACAVIR": 0.2504469800404848, "ABATACEPT": 0.7258649966035329, "ABILIFY": 0.4939095695245507, "ACLASTA": 3.124835017382656, "ADALIMUMAB": 0.502447397570364, "ADEFOVIR": 4.717083502807063, "AERIUS": 0.654074053474085, "AFINITOR": 0.1081222921642959, "ALENDRONATE": 13.441191236542306, "ALPELISIB": 1.567821272203524, "AMINOSALICYLIC": 0.7659282006671714, "APIXABAN": 0.9763006677390906, "ARAVA": 0.7529923396156554, "ATAZANAVIR": 0.8197805980686586, "ATRIPLA": 48.29826511971717, "AUBAGIO": 0.1324210573918154, "AZATHIOPRINE": 0.69218869171572, "BENLYSTA": 0.1846350333979243, "BIKTARVY": 0.998765473582336, "BONVIVA": 0.5636044577673188, "BUDESONIDE": 0.7370459214100725, "BUPIVACAINE": 0.2971027852690415, "BUSULFAN": 0.1457919479301344, "BYETTA": 0.2223623607646403, "CANAKINUMAB": 10.236979833369356, "CELLCEPT": 0.2783212456319127, "CICLOSPORIN": 0.3937733290592486, "CIMZIA": 0.199867685669887, "COMBIVIR": 0.618206782939212, "COMIRNATY": 0.0061185339424061, "COSENTYX": 0.1518899895245872, "CYMBALTA": 0.5432752497898732, "CYTARABINE": 0.1293675236357414, "DACLATASVIR": 1.0950671484377636, "DARUNAVIR": 3.107206829727565, "DENOSUMAB": 1.2544679777815582, "DESCOVY": 2.990841928683331, "DOXORUBICIN": 0.2467567559588227, "DULOXETINE": 0.8396781615570148, "EFAVIRENZ": 0.8033569877692867, "ELIQUIS": 0.2018966387458325, "EMTRICITABINE": 2.154773322619436, "EMTRIVA": 1.9278820986676144, "ENBREL": 1.2513227032974787, "ENTECAVIR": 1.0078273375303166, "EPIVIR": 0.6493775831523595, "EVENITY": 0.640015768436128, "EVISTA": 2.9999724015333338, "EXFORGE": 0.2783345169572051, "EXJADE": 0.2385592251562944, "FAMPYRA": 0.2577933144250184, "FASENRA": 0.4790402814599587, "FASLODEX": 0.4550389137761047, "FORSTEO": 0.6770838210043049, "GARDASIL": 0.032204927058436, "GENVOYA": 3.61735310944852, "HEPSERA": 7.13236119592556, "HUMALOG": 0.2429524438847237, "HUMIRA": 0.6073605725052825, "HYDROCORTISONE": 0.2935547650455867, "IBRANCE": 0.334557384103654, "INOVELON": 7.736049387581538, "INSULIN": 0.1207786278005041, "INTELENCE": 1.5616221383187854, "ISENTRESS": 0.3888308902226325, "JANUVIA": 0.232092276220339, "KALETRA": 6.878812023848671, "KEPPRA": 0.1678996256097767, "KEYTRUDA": 0.0824020481525887, "KIVEXA": 2.5657577985167404, "LAMIVUDINE": 0.4019576689134093, "LANTUS": 0.140976182194455, "LEFLUNOMIDE": 0.4034624860919303, "LEVETIRACETAM": 0.1532050958348641, "LOPINAVIR": 1.8702165296925808, "LYNPARZA": 0.276739146164087, "LYRICA": 0.2920307644428255, "MEPOLIZUMAB": 0.7034275193290163, "METHOTREXATE": 0.411682430421666, "MIMPARA": 0.5140164531767693, "MIRABEGRON": 2.106147722018445, "NORVIR": 6.157647300067522, "NUCALA": 0.2864646762822951, "OLANZAPINE": 0.0724268894125046, "OPTIMARK": 0.1027218007925756, "PEGASYS": 0.0391135214739444, "PEGINTRON": 0.0959883600378534, "PLAVIX": 0.0785171467000206, "PROLIA": 1.839799536988984, "RITONAVIR": 2.257155108783413, "RITUXIMAB": 0.5706522862064078, "SIMPONI": 0.2739737057148678, "SPIKEVAX": 0.0037935848023873, "SPIRONOLACTONE": 1.2830703458135249, "STELARA": 0.1731692559659845, "STRIBILD": 31.576430709141217, "SUTENT": 0.0340437589042399, "TASIGNA": 0.1830989307459072, "TENOFOVIR": 8.634721512900589, "TIVICAY": 1.0768109493851492, "TOVIAZ": 0.312880622904252, "TOZINAMERAN": 0.0113396587754309, "TRELEGY": 0.5519789019626321, "TRIUMEQ": 0.6858560803917176, "TRUVADA": 44.003572877467015, "VAXZEVRIA": 0.0040810148358982, "VEMLIDY": 2.444969294416385, "VIMPAT": 0.2437075742645407, "VIREAD": 22.156577081776984, "XELJANZ": 0.612614592789061, "XOLAIR": 0.2551644528608558, "XTANDI": 0.0863064786445969, "XYREM": 0.5843264704464151, "ZOSTAVAX": 1.2409507744939374, "null": 0.1857963137140741}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/864.json
index c5da5d4476e..b49973be1eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/864.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/864.json
@@ -1 +1 @@
-{"null": 1.5484320522781656}
\ No newline at end of file
+{"null": 1.4941758983171674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8640.json
index 35240fda150..afdf342bd95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8640.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8640.json
@@ -1 +1 @@
-{"BUDESONIDE": 21.00359492613627}
\ No newline at end of file
+{"ADALIMUMAB": 3.53101621530496, "ATRIPLA": 25.654476190124672, "CICLOSPORIN": 3.1209870624237235, "EVISTA": 13.79897771212123, "FORSTEO": 5.802024149413668, "STRIBILD": 4.512159499609686, "TRUVADA": 19.467346146552988, "null": 0.4033739089952079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8641.json
index d9a0cfc6ceb..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8641.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8641.json
@@ -1 +1 @@
-{"AVASTIN": 13.893190156877472, "ELIQUIS": 2.5274133666166225, "NOVOSEVEN": 169.02767191097865, "STELARA": 3.4108698464370937, "SUTENT": 6.374475723901832, "VOTRIENT": 8.453369409875581}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8642.json
index 481c574236d..336bd6862ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8642.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8642.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 64.02644450136266, "ASPARAGINASE": 11.276923933617104, "BUSILVEX": 754.830182378999, "BUSULFAN": 300.2737355872748, "CICLOSPORIN": 10.366313850738765, "CYTARABINE": 12.064854536810708, "DEFITELIO": 456.3790143771198, "EXJADE": 3.823129080982479, "METHOTREXATE": 3.6738470418348266, "ONCASPAR": 28.06381476138436}
\ No newline at end of file
+{"METHOTREXATE": 19.12970078700149, "NEXAVAR": 8.099751990899538, "THIOTEPA": 502.9693174763792, "null": 0.9177116220739574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8643.json
index 6f4fc147dbe..279b5ab91d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8643.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8643.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 27.41478251505784, "ASPARAGINASE": 59.22517512303188, "AVASTIN": 2.771774006924689, "AZACITIDINE": 14.185020840545617, "BESPONSA": 845.8717975460762, "BEVACIZUMAB": 3.338730302163613, "BLINATUMOMAB": 33.65915950516605, "BUSILVEX": 271.66230054057127, "BUSULFAN": 300.06852248616127, "CAPECITABINE": 8.272241757917357, "CARMUSTINE": 58.05605697475786, "CELLCEPT": 2.8393305411658143, "CICLOSPORIN": 5.527681596705299, "CYTARABINE": 19.927056216908294, "DEFITELIO": 648.445316678196, "DOXORUBICIN": 6.068349769367971, "FILGRASTIM": 7.766363574614862, "ICLUSIG": 6.92449043178623, "MELPHALAN": 92.23983851412775, "METHOTREXATE": 6.543758047401073, "MYCOPHENOLATE": 6.544657757662441, "PANITUMUMAB": 27.736317591500065, "THIOTEPA": 49.76301641465533}
\ No newline at end of file
+{"PAZOPANIB": 862.0287985077421, "null": 0.6959354118180171}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8644.json
index 8ec153407f8..063dfc2d118 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8644.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8644.json
@@ -1 +1 @@
-{"null": 1.3092049495297184}
\ No newline at end of file
+{"ARAVA": 4.079463528497056, "ENBREL": 8.120038451470144, "FULVESTRANT": 28.431878535116777, "LEFLUNOMIDE": 42.97338569283722, "null": 0.2335152846867589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8645.json
index 205201cf2c3..98d7d3a2f8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8645.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8645.json
@@ -1 +1 @@
-{"ELIQUIS": 7.08937327381996}
\ No newline at end of file
+{"RINVOQ": 429.4756896737913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8646.json
index aac55044b90..a5191f9ae19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8646.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8646.json
@@ -1 +1 @@
-{"null": 1.030402803648821}
\ No newline at end of file
+{"COMIRNATY": 0.6926787097813678, "COSENTYX": 10.754006474125166, "GARDASIL": 3.267371003436215, "PEGASYS": 1.9196575716302584, "SPIKEVAX": 0.4061455181260441, "STELARA": 5.195158223541724, "TOZINAMERAN": 0.6844438349100932, "VAXZEVRIA": 0.2584208155478644, "ZOSTAVAX": 12.108289354269823, "null": 0.4905195842667221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8647.json
index ce66c680178..38c297844e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8647.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8647.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 2.7225428198404957, "HUMALOG": 2.2699825726523666, "LANTUS": 2.741200331716972, "VAXZEVRIA": 1.1951136251208203, "null": 1.8875687038803517}
\ No newline at end of file
+{"AIMOVIG": 23.19477545859005, "AMIKACIN": 9.069150587417631, "ARAVA": 0.8914898021963734, "BOTULINUM": 19.599689488286455, "CELLCEPT": 2.5576690476078734, "CICLOSPORIN": 0.989861759678794, "COMBIVIR": 7.929004504899535, "COMIRNATY": 0.297787170690438, "COSENTYX": 2.273112302650226, "CYTARABINE": 2.909983131892154, "DELAMANID": 22.79196815930085, "GARDASIL": 0.8345658424930996, "INCIVO": 4.32768758828345, "INFANRIX": 39.20311069576132, "MEPOLIZUMAB": 2.527674828621503, "MMRVAXPRO": 14.109401929844422, "NUCALA": 2.0292023650904567, "PEGASYS": 1.1883250228894664, "PREVENAR": 17.943591921436607, "ROACTEMRA": 2.28366290665996, "ROTATEQ": 8.663267440188225, "SPIKEVAX": 0.174608784642949, "SYNAGIS": 25.09467310992204, "SYNFLORIX": 171.24733030314465, "VAXZEVRIA": 0.1046909551129035, "ZOSTAVAX": 3.2870277937704158, "ZYPREXA": 0.9010748541763678, "null": 1.567519211866291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8648.json
index d0dbaef3e85..476930bee9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8648.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8648.json
@@ -1 +1 @@
-{"null": 1.4418412080229217}
\ No newline at end of file
+{"COMIRNATY": 0.2109720978095565, "GARDASIL": 6.424575725180661, "MMRVAXPRO": 19.158406091721755, "ZOSTAVAX": 7.778528634986021, "null": 1.044748171551129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8649.json
index 3a593c988b8..22ae158d24c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8649.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8649.json
@@ -1 +1 @@
-{"ENTRESTO": 162.2718563149147}
\ No newline at end of file
+{"NUCALA": 12.183794627793748, "VAXZEVRIA": 0.2933602353521595, "null": 2.0457644689272647}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/865.json
index 5f4e0c6ceb7..d9a5c233244 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/865.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/865.json
@@ -1 +1 @@
-{"null": 1.185258981595379}
\ No newline at end of file
+{"CHLORHEXIDINE": 25.90289805646156, "OLANZAPINE": 6.864347476075312, "ZYPREXA": 11.130878533341958, "null": 1.924682468928569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8650.json
index c7f1177cc3a..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8650.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8650.json
@@ -1 +1 @@
-{"ENTRESTO": 35.229315701683525, "IVABRADINE": 909.621439087268}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8651.json
index 8a92d37520f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8651.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8651.json
@@ -1 +1 @@
-{"ARANESP": 1.6498943634087713, "ASPARAGINASE": 17.490025553375926, "AVASTIN": 10.272739588740585, "COMIRNATY": 1.4356023266014293, "CYTARABINE": 5.628463872028836, "ELIQUIS": 2.6543583594522384, "ENOXAPARIN": 6.836357549358131, "EVISTA": 13.779395982568392, "METHOTREXATE": 1.916678294325065, "NOVOSEVEN": 28.67044132554181, "NPLATE": 3.3918256674430105, "REGORAFENIB": 30.666122971379, "RINVOQ": 3.066795475760269, "STELARA": 1.2343783015691192, "VAXZEVRIA": 3.33970476416579}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8652.json
index 4ab221efd68..d46eb37b7b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8652.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8652.json
@@ -1 +1 @@
-{"ASPARAGINASE": 3.6051049870984873, "AVASTIN": 6.516523192323351, "COMIRNATY": 3.172521138280369, "ELIQUIS": 1.1283785378899895, "EVISTA": 10.7266069872005, "NOVOSEVEN": 26.47923832804478, "RINVOQ": 7.655034469053054, "SPIKEVAX": 1.063478212110679, "THALIDOMIDE": 11.007824549815108, "VAXZEVRIA": 3.353986083056314, "ZYPREXA": 1.5862232038316673}
\ No newline at end of file
+{"COMIRNATY": 1.742314225298307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8653.json
index 1f6941dd54b..98de43fd885 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8653.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8653.json
@@ -1 +1 @@
-{"FENTANYL": 28.332936677229466, "OPSUMIT": 80.47083746728701, "SILDENAFIL": 140.679676670132}
\ No newline at end of file
+{"COMIRNATY": 0.3604896628836471, "SPIKEVAX": 0.3193039136190136, "TOZINAMERAN": 0.7164218323332958, "VAXZEVRIA": 0.1420934105088999, "null": 0.9680946659658684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8654.json
index 8041e99893a..f0401afe8dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8654.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8654.json
@@ -1 +1 @@
-{"ABILIFY": 2.1243181289650934, "APIXABAN": 4.410217816326856, "AVANDIA": 4.790327141951398, "BENZODIAZEPINES": 105.43338101016818, "BUPIVACAINE": 12.487877859106089, "CICLOSPORIN": 1.0805154659543246, "CLOPIDOGREL": 1.555940965516274, "DEXAMETHASONE": 1.6118958701955686, "ENTRESTO": 4.719421345014501, "FENTANYL": 2.031737380088883, "IVABRADINE": 45.93901715551617, "OLANZAPINE": 4.67490220093029, "null": 3.091036117831784}
\ No newline at end of file
+{"null": 0.5234282361212452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8655.json
index dac8efcc1a6..d315290256d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8655.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8655.json
@@ -1 +1 @@
-{"BRILIQUE": 115.40500400675012, "JARDIANCE": 16.606899204954473, "TICAGRELOR": 129.26035004649873, "null": 2.253084019419624}
\ No newline at end of file
+{"null": 1.5184256102081408}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8656.json
index 0bd4a664177..afb14f0eb57 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8656.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8656.json
@@ -1 +1 @@
-{"ELIQUIS": 50.95462680899003}
\ No newline at end of file
+{"null": 4.7878702394504336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8657.json
index 65cfa4c383c..b15fb11d562 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8657.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8657.json
@@ -1 +1 @@
-{"IVABRADINE": 749.0346955618561, "SUTENT": 1.2456652895653983, "VOTRIENT": 5.371430465570555, "null": 1.1971511335013694}
\ No newline at end of file
+{"ALIMTA": 7.685290052827204, "AMIKACIN": 275.40436637700014, "AMINOSALICYLIC": 22.31138591229001, "CASPOFUNGIN": 35.92219244618255, "CICLOSPORIN": 3.024775013187711, "COMIRNATY": 0.0853274716260377, "PEMETREXED": 31.348768565678352, "TOBRAMYCIN": 174.24190923011594, "null": 2.521689308412783}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8658.json
index 9604d0aee10..7e406c2c57f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8658.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8658.json
@@ -1 +1 @@
-{"null": 1.329258115524737}
\ No newline at end of file
+{"KYMRIAH": 994.662270761931, "null": 1.213142761852697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8659.json
index facd457e0b2..16d9964df94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8659.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8659.json
@@ -1 +1 @@
-{"null": 1.910776270828323}
\ No newline at end of file
+{"null": 1.191905231702337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/866.json
index 63a3a3f4c3d..f57f3b4de9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/866.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/866.json
@@ -1 +1 @@
-{"null": 1.4103689742057834}
\ No newline at end of file
+{"ABILIFY": 5.272929246421821, "AIMOVIG": 0.8477258138465693, "ARIPIPRAZOLE": 1.7595639617753864, "ATRIPLA": 0.1402176616276943, "BIKTARVY": 1.7231743651726186, "BRINTELLIX": 4.064880602334195, "BRIVIACT": 4.902148692531389, "BUPRENORPHINE": 1.0006612672107584, "CHAMPIX": 6.476834998407813, "CLOPIDOGREL": 0.321471013560365, "COMIRNATY": 1.0513460139895874, "COMTAN": 5.431748990424147, "CYMBALTA": 2.162967827304096, "DULOXETINE": 3.509641012058608, "EBIXA": 6.05920944286743, "ELIQUIS": 0.787558983690232, "ENTRESTO": 0.5743973638871023, "EXFORGE": 1.243215605542146, "FAMPYRA": 1.6207422141704, "FORSTEO": 1.4015560111233654, "FORXIGA": 1.1172726791163867, "FYCOMPA": 4.520259805327356, "GARDASIL": 0.4981830284671943, "HEXYON": 8.161867337607076, "HUMALOG": 0.2682900572461331, "IBRANCE": 0.2808260127646308, "INFANRIX": 6.97649788629731, "JARDIANCE": 0.351000405235128, "KAFTRIO": 3.2200914085244023, "KEPPRA": 3.934438478680909, "KEYTRUDA": 0.1580369022244479, "LACOSAMIDE": 2.3270785485008907, "LANTUS": 0.2180747229255151, "LATUDA": 4.918695597125134, "LEVETIRACETAM": 3.215824000145393, "LEVODOPA": 14.09673920175693, "LEVOFLOXACIN": 0.9807050198165104, "LYRICA": 0.5188858291454803, "MMRVAXPRO": 2.9328853250945754, "NEXAVAR": 0.6831271357804514, "NOVORAPID": 0.5994044874166536, "OLANZAPINE": 3.939172427264221, "PEGASYS": 0.3154699207195893, "PEGINTERFERON": 0.679410801663802, "PEGINTRON": 0.8469197492383298, "PREGABALIN": 1.5041140569820532, "PREVENAR": 3.409385977695288, "RINVOQ": 0.864921541808108, "ROTATEQ": 4.533970063022273, "SAXENDA": 1.7716303345219309, "SHINGRIX": 0.3442202180618441, "SIFROL": 2.982740107341061, "SPIKEVAX": 0.8546697217366087, "STALEVO": 2.131198435493688, "SUBOXONE": 1.6436720125322348, "SUTENT": 0.2036085084442127, "TAMIFLU": 0.7361035839740183, "TEDUGLUTIDE": 24.28397027051843, "TOZINAMERAN": 0.241029362434438, "VAXZEVRIA": 0.5394646079819826, "VFEND": 0.5662935801875724, "VIMPAT": 2.0269299023052576, "XTANDI": 0.9040018220539277, "ZYPADHERA": 1.7488189369496483, "ZYPREXA": 3.716186082816292, "null": 1.5655595516328915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8660.json
index 88881b50811..2f24cb4ad02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8660.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8660.json
@@ -1 +1 @@
-{"null": 1.5031345491906134}
\ No newline at end of file
+{"BUSULFAN": 1021.2452803408464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8661.json
index 5cb37f03f15..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8661.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8661.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 5.159829738245159, "AVANDIA": 1.3356028089647585, "BEDAQUILINE": 7.571458519861368, "BRIDION": 3.839433302629269, "BRILIQUE": 2.075280935693549, "BUPIVACAINE": 2.464671298135256, "COMBIVIR": 1.826415606932068, "DAPAGLIFLOZIN": 6.707882515398371, "EDOXABAN": 34.48891310749317, "EMPAGLIFLOZIN": 4.039213431661975, "ENTRESTO": 5.12228443675819, "EXFORGE": 2.04097172482194, "FENTANYL": 4.135826132847813, "FIRDAPSE": 3.630375204402277, "IVABRADINE": 17.103482821467775, "KALETRA": 1.15713868074529, "MICARDIS": 1.898049843982526, "MIDAZOLAM": 4.772773538230685, "MULTAQ": 8.343785143255133, "OLANZAPINE": 1.1332623134089528, "SAXENDA": 1.6134009510281822, "SPIRONOLACTONE": 3.746539828197271, "SUFENTANIL": 4.634709394888435, "TASIGNA": 2.034533105756093, "TRISENOX": 15.59342619253204, "VFEND": 4.020654006826653, "VIAGRA": 1.6617602649476664, "VORICONAZOLE": 2.5093890697269887, "ZYPREXA": 1.7702159827798785, "null": 1.940088248501053}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8662.json
index aad2441dbcf..cd57cca0d5f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8662.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8662.json
@@ -1 +1 @@
-{"null": 1.4676100199403666}
\ No newline at end of file
+{"FORSTEO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8663.json
index b4bf6109a6e..14e5e504aef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8663.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8663.json
@@ -1 +1 @@
-{"ANGIOX": 28.014567990503814, "ARANESP": 8.992294284558822, "AVANDAMET": 4.765279158410529, "AVANDIA": 6.730305156216914, "BRIDION": 16.16556455257251, "BRILIQUE": 1.5362329875488792, "CHAMPIX": 1.089713848294307, "CLOPIDOGREL": 1.7106203450092572, "DARBEPOETIN": 42.8886923875399, "DEXAMETHASONE": 1.2423229332153911, "ENTRESTO": 3.982400600795079, "FENTANYL": 5.765802977874911, "FLUTICASONE": 62.3814075546732, "IRBESARTAN": 5.353085921616906, "IVABRADINE": 13.381774976491432, "LEVETIRACETAM": 1.2161122766103163, "LEVOFLOXACIN": 1.876097785476419, "MEXILETINE": 43.55973498245247, "MIDAZOLAM": 5.5421267164729375, "MULTAQ": 7.301459660059155, "NORVIR": 2.601898624979444, "NOXAFIL": 3.404301669823714, "OLANZAPINE": 1.448645419268615, "PLAVIX": 1.1216932951730771, "PROPRANOLOL": 5.5355374065443606, "RANOLAZINE": 8.780738603230352, "RASBURICASE": 29.93153726263183, "SILDENAFIL": 1.846410077000791, "TAGRISSO": 1.4325759996725782, "TRACLEER": 1.1290290106611507, "VFEND": 3.5179796227732254, "VIAGRA": 3.739327185404726, "VIMPAT": 2.128275978840651, "ZYPREXA": 1.149124021287649, "null": 3.1121852684431253}
\ No newline at end of file
+{"ARAVA": 0.4063268471803032, "AUBAGIO": 2.0561271761127498, "AVASTIN": 4.4317581182727, "BEVACIZUMAB": 5.365176954752971, "CAELYX": 27.03620824413983, "COMIRNATY": 0.0663700309614641, "COSENTYX": 0.9292657389581211, "CYMBALTA": 0.4907190445136834, "ELIQUIS": 1.1355869689610756, "EVISTA": 21.56544297691745, "FORSTEO": 2.204324663928343, "HUMALOG": 1.2395077448160416, "IBRANCE": 0.9976954914983688, "LANTUS": 1.754333012857494, "LYNPARZA": 13.915296651010422, "MVASI": 41.772609923864295, "NEULASTA": 5.034572934410719, "NPLATE": 5.093898146353857, "OLANZAPINE": 2.659419105763911, "ROACTEMRA": 2.249804784902038, "RUBRACA": 6.22399101680361, "SIMPONI": 2.202566474507341, "STELARA": 1.513952921082935, "XELJANZ": 1.2051098942978724, "XOLAIR": 1.3488449966914615, "null": 3.061036761631031}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8664.json
index 5401776b47f..01a16eee236 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8664.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8664.json
@@ -1 +1 @@
-{"null": 3.913732912441447}
\ No newline at end of file
+{"RUBRACA": 61.51599018863623, "null": 2.267143457851961}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8665.json
index b289e8ed6eb..c392ab3af45 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8665.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8665.json
@@ -1 +1 @@
-{"ENTRESTO": 86.58848158698123, "null": 1.9278588677871185}
\ No newline at end of file
+{"LYNPARZA": 856.5156125474496, "OLAPARIB": 228.44150019229264, "RUBRACA": 719.381654576542, "null": 0.1124733013846538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8666.json
index 02b29c7cdf8..14cc7e63366 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8666.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8666.json
@@ -1 +1 @@
-{"AVANDIA": 4.085527961301992, "AVASTIN": 8.9608551125142, "ISENTRESS": 25.409631078271623, "PANTOPRAZOLE": 38.86235888093664, "null": 2.1462261752809484}
\ No newline at end of file
+{"null": 0.678886286560392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8667.json
index 404fccdd9ee..7e4ac3e0310 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8667.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8667.json
@@ -1 +1 @@
-{"ACLIDINIUM": 94.36227366591687, "ARIPIPRAZOLE": 3.842878452608796, "CICLOSPORIN": 1.0486094087726403, "CLOPIDOGREL": 5.800013798325373, "DAPAGLIFLOZIN": 38.78542489575379, "ENTRESTO": 5.468852504959744, "FENTANYL": 7.549402174713726, "ICLUSIG": 6.815515388489292, "IRBESARTAN": 9.683128779864218, "MEKINIST": 4.581137954754486, "METHOTREXATE": 2.60507311346161, "OLANZAPINE": 1.4148639824622973, "PANTOPRAZOLE": 18.019966680824023, "VALSARTAN": 24.023510920868613, "null": 1.4673500974491631}
\ No newline at end of file
+{"AFINITOR": 2.7381745750860524, "AIMOVIG": 3.138134052260781, "ARAVA": 0.7858695046696301, "CANNABIDIOL": 18.36312986808593, "CELLCEPT": 10.50993716595165, "CHLORHEXIDINE": 3.990926106543789, "CIMZIA": 1.5684731697009289, "COMIRNATY": 1.0998113875116309, "DACLIZUMAB": 614.8969261647052, "ESMYA": 43.09269855841772, "FORSTEO": 1.3706540954211135, "GARDASIL": 7.271329271376039, "GONALF": 35.14290471709158, "JANUVIA": 1.967181420416416, "LANTUS": 0.636443941388419, "LYRICA": 1.601100244740699, "OMALIZUMAB": 1.9751994539714284, "PEGASYS": 0.6524839267496992, "SILDENAFIL": 5.194485959881008, "SIMPONI": 2.2468844852654364, "SOLIRIS": 1.5419141380289298, "SPIKEVAX": 0.3557773061130388, "STELARA": 0.7426177849967871, "SUBOXONE": 2.2386792417100123, "TOZINAMERAN": 0.6138888986322426, "VAXZEVRIA": 0.2201711855808814, "XELJANZ": 1.164550487205391, "XOLAIR": 1.6059032923727223, "null": 1.0983407133121723}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8668.json
index 78d17d8d1af..2b76317ea1c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8668.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8668.json
@@ -1 +1 @@
-{"CYMBALTA": 12.47745812141054, "null": 2.413910384021141}
\ No newline at end of file
+{"COMIRNATY": 0.8777170926384561, "GARDASIL": 9.585506318345404, "TOZINAMERAN": 1.413712832329752, "null": 0.5758406170507805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8669.json
index e0dcb56b640..8c56eb39af0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8669.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8669.json
@@ -1 +1 @@
-{"ALISKIREN": 7.093957810134874, "COMBIVIR": 5.457577702051131, "EMTRICITABINE": 30.86111790984014, "HUMALOG": 1.335659185635229, "IBUPROFEN": 4.285084760815094, "ISENTRESS": 18.74448073602423, "KALETRA": 5.871981359906349, "KEPPRA": 3.4774512030482283, "LEVEMIR": 4.34426985822138, "LEVETIRACETAM": 6.312468236404844, "NORVIR": 16.849989176550306, "null": 5.98437748005421}
\ No newline at end of file
+{"CIMZIA": 11.15823879620858, "COMIRNATY": 0.5011519406688681, "IBRANCE": 7.079411838230755, "null": 0.8243569658605395}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/867.json
index 326a94e8f38..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/867.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/867.json
@@ -1 +1 @@
-{"ARAVA": 4.60588286202586, "null": 1.1222986827809127}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8670.json
index 370bf8467ef..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8670.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8670.json
@@ -1 +1 @@
-{"null": 2.0411844031868918}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8671.json
index a9dde1c47c5..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8671.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8671.json
@@ -1 +1 @@
-{"ALISKIREN": 3.897876771030065, "AMIODARONE": 52.8856459910641, "APIXABAN": 2.82057731676507, "ATAZANAVIR": 1.188683347145585, "AVANDAMET": 7.567434640734304, "AVANDIA": 7.049131529894732, "BRIDION": 7.08459421881965, "BRILIQUE": 1.4056401230515407, "BUMETANIDE": 7.952151309760993, "BUPIVACAINE": 3.891210293591878, "CLOPIDOGREL": 2.553990895478468, "CUBICIN": 1.2524762921120547, "DAPAGLIFLOZIN": 6.499412033124952, "DASATINIB": 5.100527383854425, "DEXAMETHASONE": 1.2547656513939884, "EDOXABAN": 26.37813993367104, "ENOXAPARIN": 1.110025555318705, "ENTRESTO": 8.380094961380163, "EPIVIR": 2.4952011923170843, "FENTANYL": 6.070580028612318, "GLUCAGON": 9.349221107426205, "HARVONI": 1.2265985657485143, "JARDIANCE": 1.0780557003687938, "LACOSAMIDE": 4.637612025704618, "LEVETIRACETAM": 1.0432762529754602, "LEVOFLOXACIN": 2.695293217748934, "MEXILETINE": 61.56323827028558, "MICARDIS": 1.4099821456172514, "MIDAZOLAM": 3.272706574472644, "MULTAQ": 15.582914583588828, "NOT": 2.27077666268135, "NOXAFIL": 2.1577874157700605, "OLANZAPINE": 1.8356469417445496, "PANTOPRAZOLE": 1.635680948894322, "POSACONAZOLE": 5.101424818547481, "PROPRANOLOL": 3.264167633605167, "RANEXA": 6.273515621681442, "RANOLAZINE": 12.108423842729298, "REBETOL": 2.512822708227409, "REYATAZ": 3.6456469519206514, "SILDENAFIL": 3.770439724460064, "SPIRONOLACTONE": 5.605748626842942, "SUFENTANIL": 2.9120515816660024, "TAGRISSO": 1.6553833398969355, "TAMIFLU": 1.3191533768312915, "TRACLEER": 1.2642594133818192, "TRISENOX": 19.27148991246068, "VALSARTAN": 5.62074393667376, "VFEND": 2.8414237504908613, "VIAGRA": 1.5256788396939855, "VILDAGLIPTIN": 26.00611653007701, "VIMPAT": 1.390285922252924, "VORICONAZOLE": 1.74661841114549, "ZYPREXA": 1.0780170688163628, "null": 3.2956698300438942}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8672.json
index 9bb231adb8e..9fd30414e87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8672.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8672.json
@@ -1 +1 @@
-{"CHAMPIX": 20.19304384989637, "null": 1.8893301426137727}
\ No newline at end of file
+{"COMIRNATY": 0.2032167110739307, "GONALF": 1090.829249503586, "null": 0.9434986890421204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8673.json
index 8ca83ebc4ae..5964ec2bdf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8673.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8673.json
@@ -1 +1 @@
-{"COMIRNATY": 2.6995265656087755}
\ No newline at end of file
+{"EVISTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8674.json
index 408dd9220d2..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8674.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8674.json
@@ -1 +1 @@
-{"TASIGNA": 93.88610492639148}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8675.json
index 4cb3e304b25..3491cb4bf8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8675.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8675.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0352893892793984}
\ No newline at end of file
+{"VICTOZA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8676.json
index c50035f454d..d1e626e70a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8676.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8676.json
@@ -1 +1 @@
-{"ATRIPLA": 14.771258551862829, "STRIBILD": 22.88510668025476, "TRUVADA": 6.783656917901483, "ZOSTAVAX": 12.821176609450546}
\ No newline at end of file
+{"BUSULFAN": 265.4898838320304, "COMIRNATY": 0.2735263416373161, "GARDASIL": 17.649250192178776, "null": 0.8093783373489642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8677.json
index 37fa30287e8..3a1e4dbb2e2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8677.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8677.json
@@ -1 +1 @@
-{"null": 1.1552532498597876}
\ No newline at end of file
+{"VIREAD": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8678.json
index 0c00d2f5ea0..28392b2ef5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8678.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8678.json
@@ -1 +1 @@
-{"ATRIPLA": 4.343362834592239}
\ No newline at end of file
+{"INVEGA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8679.json
index 51e5de7f435..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8679.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8679.json
@@ -1 +1 @@
-{"COMIRNATY": 2.046638415200725}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/868.json
index 84066267e72..5c425c6696e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/868.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/868.json
@@ -1 +1 @@
-{"null": 1.0719943210197278}
\ No newline at end of file
+{"FENTANYL": 47.96208484926404, "null": 1.014706308781459}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8680.json
index a5b4e877e86..7cc425e585b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8680.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8680.json
@@ -1 +1 @@
-{"FORSTEO": 190.75191381203325}
\ No newline at end of file
+{"null": 0.5519605119142673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8681.json
index d1913d0d6c4..07648dacfbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8681.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8681.json
@@ -1 +1 @@
-{"null": 1.1093951489826523}
\ No newline at end of file
+{"SPINRAZA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8682.json
index a64a989cffb..0f20649561a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8682.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8682.json
@@ -1 +1 @@
-{"null": 1.550517434167808}
\ No newline at end of file
+{"PACLITAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8683.json
index 4be6907f4f7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8683.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8683.json
@@ -1 +1 @@
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\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8684.json
index 3bbd33e1810..ebe71bded9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8684.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8684.json
@@ -1 +1 @@
-{"COVID19": 1.707935829705548, "null": 1.695933139054759}
\ No newline at end of file
+{"COMIRNATY": 0.4456828761975359, "GONALF": 300.5133259276359, "null": 1.3878501484203587}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8685.json
index 6506dc907bd..fdd00058e20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8685.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8685.json
@@ -1 +1 @@
-{"CELECOXIB": 20.696113086729703, "COMIRNATY": 2.937412103383491, "COVID19": 1.9785066834382767, "DEXAMETHASONE": 1.5457008732745958, "FORSTEO": 1.4322487252529217, "SPIKEVAX": 1.868375316974302, "TOZINAMERAN": 2.162057360441903, "VAXZEVRIA": 1.066615901665838, "ZOSTAVAX": 3.678494900597949}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8686.json
index 65faef368a2..e16b2b7f95f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8686.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8686.json
@@ -1 +1 @@
-{"null": 1.071962840808923}
\ No newline at end of file
+{"BUSULFAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8687.json
index 5f87dfd4043..faa6172baa6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8687.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8687.json
@@ -1 +1 @@
-{"null": 2.2990917653458}
\ No newline at end of file
+{"ARAVA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8688.json
index 925984eb1a5..1b2a0cf4b70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8688.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8688.json
@@ -1 +1 @@
-{"null": 1.0379271266124754}
\ No newline at end of file
+{"null": 0.7926968853379056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8689.json
index 6155c3a27b1..4cb04c0cff1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8689.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8689.json
@@ -1 +1 @@
-{"null": 1.9014649402371044}
\ No newline at end of file
+{"ARAVA": 3.824464016120521, "null": 0.5880507822637548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/869.json
index f4518bbcd0b..adcdc16c8a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/869.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/869.json
@@ -1 +1 @@
-{"VICTOZA": 39.72980162554838, "null": 1.0021224330468554}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8690.json
index 8dff1301c60..6c7be202c00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8690.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8690.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 19.251765545116157, "PLAVIX": 20.92612543442221, "null": 1.254287808086463}
\ No newline at end of file
+{"null": 0.9514018175904208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8691.json
index 584999665b6..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8691.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8691.json
@@ -1 +1 @@
-{"PLAVIX": 16.52545001629515, "null": 1.7020046849041066}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8692.json
index 0191755848b..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8692.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8692.json
@@ -1 +1 @@
-{"null": 5.76590816283194}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8693.json
index f771f620527..8a47a830f9b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8693.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8693.json
@@ -1 +1 @@
-{"null": 2.182707492679382}
\ No newline at end of file
+{"null": 3.538374876179618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8694.json
index cbff57dbc01..29baecd8167 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8694.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8694.json
@@ -1 +1 @@
-{"AIMOVIG": 6.498008729751371, "CELECOXIB": 43.78855048876494, "CHAMPIX": 2.1797978962936613, "COMIRNATY": 1.414955416371805, "CYMBALTA": 1.385589420344014, "DEXAMETHASONE": 3.2434289973379284, "TOZINAMERAN": 1.4658469543757957}
\ No newline at end of file
+{"BARACLUDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8695.json
index 657e4e32c30..451d8dcad8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8695.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8695.json
@@ -1 +1 @@
-{"AIMOVIG": 14.547280768195286, "COVID19": 3.306951015282894, "TOZINAMERAN": 6.930457399542347}
\ No newline at end of file
+{"COMIRNATY": 0.9991163921007418, "ELIQUIS": 26.50524912145501}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8696.json
index 584ee5ffa76..c6490dabd28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8696.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8696.json
@@ -1 +1 @@
-{"COMIRNATY": 5.668415775293667, "COVID19": 1.130267895865268, "SHINGRIX": 2.025822824028672, "SPIKEVAX": 1.9324390466574424, "TOZINAMERAN": 2.062572706111652, "VAXZEVRIA": 1.4094406734781617, "ZOSTAVAX": 2.4643476771286768}
\ No newline at end of file
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8697.json
index c64923f42a9..410421e2148 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8697.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8697.json
@@ -1 +1 @@
-{"SUBOXONE": 65.32206147932757}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8698.json
index 7c82a9ecb70..a8b4ea352ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8698.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8698.json
@@ -1 +1 @@
-{"null": 10.942081740626808}
\ No newline at end of file
+{"null": 1.071196682677953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8699.json
index ae0767c7e14..f2e4b0fba50 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8699.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8699.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 113.05093529601352, "null": 1.3279972534965905}
\ No newline at end of file
+{"ENTYVIO": 56.06992138782134, "null": 1.1619192809764267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/87.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/87.json
index d958d086429..0f3239ff66e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/87.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/87.json
@@ -1 +1 @@
-{"CICLOSPORIN": 34.195124713376366}
\ No newline at end of file
+{"COMIRNATY": 0.3577637072705905, "FENTANYL": 20.64000328673334, "null": 0.6409058667978519}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/870.json
index 170a6b1a2ff..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/870.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/870.json
@@ -1 +1 @@
-{"METHOTREXATE": 39.32899244457196}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8700.json
index bb62afd5be3..480d58f7250 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8700.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8700.json
@@ -1 +1 @@
-{"SUBOXONE": 76.69416857038044, "null": 1.075788706140475}
\ No newline at end of file
+{"ADCIRCA": 169.2042777497253, "AZATHIOPRINE": 60.37562861845094, "COMIRNATY": 0.3008826305202797, "null": 0.5220659796237705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8701.json
index ce9b7f202d2..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8701.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8701.json
@@ -1 +1 @@
-{"null": 3.875373024164392}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8702.json
index a6507aac5fb..5a41e5fb3ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8702.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8702.json
@@ -1 +1 @@
-{"SUBOXONE": 36.7926682516745, "null": 4.329886383123141}
\ No newline at end of file
+{"COMIRNATY": 1.646106990019319, "SPIKEVAX": 0.944402059006238, "TOZINAMERAN": 4.34009735474165, "VAXZEVRIA": 3.9956211927339895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8703.json
index aaef73815e5..044b1beafec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8703.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8703.json
@@ -1 +1 @@
-{"ABILIFY": 6.051443351995413, "CHAMPIX": 54.3131394415617, "CYMBALTA": 2.8368665638548527, "LATUDA": 10.704638481319, "OLANZAPINE": 7.465011213617355, "PEGASYS": 4.367869339207155, "PEGINTRON": 3.662840562905101, "null": 2.289713277701801}
\ No newline at end of file
+{"ASPARAGINASE": 12.29160763943474, "AVAMYS": 49.29021142016296, "BYETTA": 4.594623835629918, "COMIRNATY": 0.0450662123684494, "COSENTYX": 2.287228023773454, "ELIQUIS": 1.5311694421757007, "GARDASIL": 0.9888307236011086, "HUMALOG": 4.336293904284255, "IBRANCE": 1.2120894048880582, "KEPPRA": 1.0072027446908902, "LANTUS": 1.3425144704038745, "LYRICA": 2.724130682166755, "OLANZAPINE": 5.306368974698866, "RINVOQ": 3.582355717443691, "SUBOXONE": 4.170405452496121, "TOVIAZ": 6.977681065854134, "TOZINAMERAN": 0.2071386912512935, "TREMFYA": 6.107930678714003, "XELJANZ": 1.1258471067722893, "ZOSTAVAX": 14.15139304471794, "ZYPREXA": 4.157780558618842, "null": 1.3818223138143555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8704.json
index e2503661664..33f85f2636f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8704.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8704.json
@@ -1 +1 @@
-{"ABACAVIR": 8.725279691354764, "ALEMTUZUMAB": 102.06373233725432, "ASPARAGINASE": 119.14962675355363, "BIKTARVY": 222.2101632400498, "CICLOSPORIN": 4.528090599267239, "CYMBALTA": 4.337558439054439, "CYTARABINE": 18.039951093088472, "DARUNAVIR": 35.77081299102465, "MELPHALAN": 69.34003307326786, "PEGINTERFERON": 12.363230589761692}
\ No newline at end of file
+{"COMIRNATY": 11.379808062889646, "SPIKEVAX": 1.8013818699556214, "TOZINAMERAN": 2.575830490439291, "VAXZEVRIA": 0.4080257287508211}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8705.json
index 87a93cb6daa..8df74ec7983 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8705.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8705.json
@@ -1 +1 @@
-{"ENTRESTO": 57.868689420113824}
\ No newline at end of file
+{"COMIRNATY": 8.957721546042796, "SPIKEVAX": 1.4863164640084057, "TOZINAMERAN": 2.0237710111336984, "null": 0.0872245038696489}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8706.json
index 9fddc2727b0..042dc07c9e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8706.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8706.json
@@ -1 +1 @@
-{"ALEMTUZUMAB": 25.892772364661948, "ASPARAGINASE": 20.089670572403808, "BUSULFAN": 247.341756697426, "CELLCEPT": 26.403661823082818, "CICLOSPORIN": 51.13065306067522, "METHOTREXATE": 8.128413012723303, "MYCOPHENOLATE": 86.586966690326}
\ No newline at end of file
+{"COMIRNATY": 10.294883938604231, "SPIKEVAX": 2.470108668783436, "TOZINAMERAN": 2.695216238770968, "VAXZEVRIA": 0.5789318604245658, "null": 0.0533284058336825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8707.json
index e1700c7d0a2..96d01983cd5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8707.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8707.json
@@ -1 +1 @@
-{"ADEFOVIR": 24.28293418155065, "ALEMTUZUMAB": 2.633146529383555, "ANAKINRA": 1.1707271714141845, "ASPARAGINASE": 27.161805730258617, "AZATHIOPRINE": 2.283382891570792, "BEDAQUILINE": 1.2599464982237412, "BENLYSTA": 3.36515911267273, "BUSULFAN": 5.560984792106985, "CELLCEPT": 4.294545424283374, "CICLOSPORIN": 3.112165841892755, "CIMZIA": 1.5984264789606308, "COMBIVIR": 1.012991264191845, "COSENTYX": 1.7592189791993762, "CYTARABINE": 2.0753429258254905, "ENBREL": 2.8276648746278634, "ENTYVIO": 1.7102993575125276, "ESBRIET": 1.3187979875198632, "EXJADE": 2.1822166174237823, "FAMPYRA": 1.910937367909629, "FASENRA": 3.739458991447773, "FILGRASTIM": 4.9977116655340055, "FIRDAPSE": 4.3644019595714205, "GARDASIL": 4.218242778195194, "HEPSERA": 3.203725538308833, "HIZENTRA": 4.502516505989992, "HUMALOG": 1.712108766009366, "IBRANCE": 1.7320250978493974, "ICLUSIG": 1.2799577657636478, "INCRUSE": 3.357708832804083, "INFANRIX": 4.231417485719541, "IRON": 3.604552430147829, "JAKAVI": 1.3846881818445795, "KAFTRIO": 6.68377693789446, "KALETRA": 1.107166004289267, "KALYDECO": 12.728518357098013, "LEMTRADA": 1.5049893749563057, "MENVEO": 3.609901953220176, "MEPOLIZUMAB": 7.512845545202341, "MERCAPTOPURINE": 4.01416988430293, "METHOTREXATE": 2.7474832173091137, "MMRVAXPRO": 2.170415844695514, "NAGLAZYME": 5.774838559797415, "NPLATE": 2.617038220945177, "NUCALA": 2.2828609024379247, "OCALIVA": 2.96029910183373, "OMALIZUMAB": 1.4152226803191372, "OPSUMIT": 2.1651339600365325, "ORENCIA": 10.36460480020837, "ORKAMBI": 9.85631440855826, "PEGASYS": 1.350239834626192, "PEGINTERFERON": 1.1385851543389671, "PLEGRIDY": 1.6134862230867268, "PREVENAR": 10.499621307716886, "RAPAMUNE": 2.90250774340575, "REVATIO": 1.4574255629696966, "RINVOQ": 1.7814820365555646, "ROACTEMRA": 1.3809717615231265, "ROTATEQ": 3.917497209711664, "RUBRACA": 1.59078498946069, "SIMPONI": 8.309281132716972, "SOLIRIS": 8.17613756144806, "SOMATROPIN": 4.7167327495039295, "SPINRAZA": 13.003892029886169, "SPRYCEL": 1.039558973997452, "STELARA": 3.2153666793620825, "SUTENT": 1.061962163155351, "SYNAGIS": 20.80593853914922, "TRACLEER": 3.599241436131178, "TRELEGY": 2.9469089194913227, "TREMFYA": 1.160072440318891, "TWINRIX": 1.6724807286758618, "VELTASSA": 2.1320334894862145, "VFEND": 1.8604347105440453, "VICTOZA": 1.204280085816963, "XELJANZ": 4.501724042068621, "XOLAIR": 4.297590070120743, "ZOSTAVAX": 1.4195873950231153}
\ No newline at end of file
+{"null": 2.1811474582026085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8708.json
index 17ac052abcf..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8708.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8708.json
@@ -1 +1 @@
-{"BIKTARVY": 170.87287612535974}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8709.json
index 7236ea2bbea..d728615f792 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8709.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8709.json
@@ -1 +1 @@
-{"BIKTARVY": 663.6979522012074}
\ No newline at end of file
+{"null": 2.90040005488522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/871.json
index d3f61a018a5..a0f8a5a42cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/871.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/871.json
@@ -1 +1 @@
-{"BYETTA": 72.36487152243265}
\ No newline at end of file
+{"ABACAVIR": 0.3305083350006793, "ABILIFY": 0.4925633841975136, "AFINITOR": 0.5828366833099208, "AIMOVIG": 2.923746329248005, "ALEMTUZUMAB": 0.8580838824186303, "ALISKIREN": 42.99519541246691, "APIDRA": 0.9558860519151025, "APIXABAN": 0.2015066586983024, "ARAVA": 0.0513552875834742, "ARIPIPRAZOLE": 1.3145433796291304, "ASPARAGINASE": 0.5166626887257173, "AUBAGIO": 1.886969552376278, "AVANDIA": 0.7531968324840737, "AVASTIN": 0.693551796662227, "AZILECT": 9.767889780209902, "BENLYSTA": 1.3096917549784963, "BEVACIZUMAB": 0.7256105425226547, "BOTULINUM": 4.262958088804281, "BRAFTOVI": 0.603378585469463, "BRILIQUE": 1.142192626718684, "BRINTELLIX": 0.5511205592995829, "BRIVIACT": 2.0316948037832887, "BUPIVACAINE": 1.5940581907226192, "BUSULFAN": 0.6135575117760794, "CELLCEPT": 0.6068187363049985, "CHAMPIX": 0.8379251197439725, "CICLOSPORIN": 0.871961012559017, "CLOPIDOGREL": 2.052403278373098, "COMIRNATY": 1.1074888013614224, "COSENTYX": 0.3023352007622458, "CYMBALTA": 0.8989631624992045, "CYTARABINE": 1.4154836821350043, "DEXAMETHASONE": 0.8247150161261497, "DOCETAXEL": 0.3818739490279317, "DOLUTEGRAVIR": 3.722152370413929, "DULOXETINE": 1.1390431488559063, "ELIQUIS": 1.601812568324365, "ENBREL": 0.1634104467327164, "ENOXAPARIN": 2.3682076340175824, "ENTRESTO": 0.4864634175465923, "ENTYVIO": 0.5664877230809667, "ESOMEPRAZOLE": 1.5154439447793553, "EVISTA": 1.609482462219146, "EXFORGE": 0.4081243444018091, "EXJADE": 0.3968808117784214, "EYLEA": 1.292425778080066, "FAMPYRA": 0.5556505825775891, "FASENRA": 0.67403332690539, "FENTANYL": 0.4973981293837765, "FESOTERODINE": 49.54106005035204, "FILGRASTIM": 1.64958200885699, "FIRDAPSE": 2.17303991250418, "FORSTEO": 0.5387800223793705, "GARDASIL": 0.967150304510482, "HUMALOG": 0.9964813324254784, "HUMAN": 0.7487935987634332, "IBRANCE": 0.3906666966548836, "IBUPROFEN": 0.4169923367218276, "ICLUSIG": 1.5303100469305864, "INFANRIX": 1.897709755233314, "INLYTA": 0.7976165481402335, "INSULIN": 0.7401604543775921, "IRBESARTAN": 1.937157519113676, "IRESSA": 0.6224544680285045, "IRINOTECAN": 1.5777120586152231, "JAKAVI": 0.6449760971709377, "JANUMET": 0.2356803719481761, "JANUVIA": 0.4163294027595994, "JARDIANCE": 0.2193168159394447, "KALETRA": 0.4312858073143256, "KEPPRA": 3.3101144596496765, "KEYTRUDA": 0.4301075719213034, "KYMRIAH": 3.97509849087988, "LACOSAMIDE": 2.7489829877777985, "LAMIVUDINE": 0.9692510680362946, "LANTUS": 1.2999638877931892, "LATUDA": 0.9069204068557968, "LEMTRADA": 1.0916449060690403, "LEVETIRACETAM": 1.695552870595994, "LEVOFLOXACIN": 0.5179379093006474, "LIXIANA": 1.0273725957576263, "LYRICA": 1.2853777813962424, "MEKINIST": 0.9711866397431904, "METHOTREXATE": 0.4158831295156275, "MIDAZOLAM": 0.6829361021908361, "MISOPROSTOL": 20.77022373158293, "MMRVAXPRO": 0.2449809896067968, "NEXAVAR": 0.7317912301815221, "NOVONORM": 4.743210234793339, "NUCALA": 0.2184307358229737, "OFEV": 1.3408411037761174, "OLANZAPINE": 0.7034958707135127, "PEGASYS": 0.5476780772597173, "PEGINTERFERON": 0.6545265887425354, "PEGINTRON": 1.1004120576889145, "PLAVIX": 1.3826797001865374, "PREGABALIN": 0.5664963276788232, "REMICADE": 0.9615268861588082, "RISPERIDONE": 1.331474624251931, "RIVAROXABAN": 2.897060795711641, "ROACTEMRA": 0.643264790355959, "RUBRACA": 1.068953563173915, "SHINGRIX": 0.9290081485090704, "SOLIRIS": 0.5940631890133882, "SPIKEVAX": 0.7801714328902347, "STALEVO": 1.4270800560195709, "STELARA": 0.370037641252846, "STIVARGA": 0.2788873504362936, "SUBOXONE": 0.4722282767950119, "SUTENT": 0.7150915482175115, "TAMIFLU": 0.6035344283496045, "TASIGNA": 1.5312861428474993, "TEMODAL": 2.679084608244679, "TEMOZOLOMIDE": 3.803726376746415, "THALIDOMIDE": 1.7643733313073386, "TOZINAMERAN": 0.7524731196230643, "TRACLEER": 0.3339525802538827, "TRELEGY": 0.4225154324033784, "TRULICITY": 0.3880295329121416, "TWINRIX": 0.9826380053802652, "VAXZEVRIA": 0.6126499658069644, "VFEND": 0.3791888682497258, "VIAGRA": 0.5004251834673918, "VIMPAT": 2.7496770209476336, "VOTRIENT": 0.8250063462588922, "XARELTO": 0.9581105795908756, "XELJANZ": 0.3905420858959632, "XOLAIR": 0.3886676021690694, "XTANDI": 0.6814631728152537, "YESCARTA": 13.94436212972964, "ZOSTAVAX": 0.3975857523151395, "ZYPADHERA": 1.6043326336610573, "ZYPREXA": 0.7726152487138667, "null": 1.317045403514055}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8710.json
index 007670fbeaa..d4dfaa7a666 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8710.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8710.json
@@ -1 +1 @@
-{"BIKTARVY": 137.51745744674574, "COMBIVIR": 237.65736056839475, "PEGASYS": 16.132272360540007}
\ No newline at end of file
+{"COMIRNATY": 0.5730278957708694, "null": 1.3480299986991842}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8711.json
index c6661e1f4ce..fc400459f23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8711.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8711.json
@@ -1 +1 @@
-{"ABACAVIR": 4.006606114955514, "ADEFOVIR": 155.48106806424838, "ATAZANAVIR": 24.187752007122715, "ATRIPLA": 2.937051567944192, "BARACLUDE": 166.47896318073563, "BIKTARVY": 128.68420443678886, "CABOTEGRAVIR": 207.4362275517437, "CELLCEPT": 1.0330299377025256, "COMBIVIR": 7.794316609638822, "DAKLINZA": 12.881783917569264, "DARUNAVIR": 26.852048780969945, "DESCOVY": 43.65226576249108, "DOLUTEGRAVIR": 25.150319199271856, "EFAVIRENZ": 26.47656970226932, "EMTRICITABINE": 18.884105716020542, "ENTECAVIR": 102.31203578379056, "GANCICLOVIR": 15.384479018341914, "GENVOYA": 124.54115527873388, "HARVONI": 5.1893987753290105, "HEPSERA": 73.73402075593185, "INCIVO": 13.896632287420111, "ISENTRESS": 10.083610546482534, "KALETRA": 25.4041516903568, "LAMIVUDINE": 8.295727128053338, "NORVIR": 18.752262737242443, "OLYSIO": 40.2837904915344, "PEGASYS": 22.90058888141333, "PEGINTERFERON": 6.039716537112199, "PEGINTRON": 3.5837865174260566, "REKAMBYS": 155.6588293864485, "REYATAZ": 38.12423962785753, "RIBAVIRIN": 13.45464430674092, "SOVALDI": 23.913711484866848, "STRIBILD": 9.588219359523416, "SYMTUZA": 104.16448448730864, "TENOFOVIR": 51.89174899445597, "TIVICAY": 42.6312920656961, "TRIUMEQ": 21.478645110576345, "TRUVADA": 4.756791089592164, "VEMLIDY": 72.46452354431024, "VIREAD": 62.40505438352553}
\ No newline at end of file
+{"OFEV": 26.952328427651786, "OPSUMIT": 91.21566594544592, "TRACLEER": 29.742254816213222, "null": 0.8703433555203981}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8712.json
index 97911c67df3..cb6d1d92ea1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8712.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8712.json
@@ -1 +1 @@
-{"ABACAVIR": 77.8069111877787, "ATAZANAVIR": 64.9706700637612, "BIKTARVY": 17.591802484957203, "CABOTEGRAVIR": 277.473330570674, "CELSENTRI": 91.43272044930563, "COMBIVIR": 13.018284079113114, "DACLATASVIR": 149.25009093444734, "DAKLINZA": 77.95247564998206, "DARUNAVIR": 142.38259860508552, "DOLUTEGRAVIR": 183.7559197868926, "EFAVIRENZ": 62.81485457310976, "EMTRICITABINE": 48.289062039213576, "ENTECAVIR": 71.60971291362493, "GANCICLOVIR": 35.3663445773665, "HARVONI": 94.03920278309782, "HEPSERA": 52.85393391499872, "ISENTRESS": 21.07158443967743, "LAMIVUDINE": 118.0984434626281, "OLYSIO": 12.719277201096364, "RIBAVIRIN": 28.356824525381988, "STRIBILD": 7.4161622485859, "TIVICAY": 23.3951337681442, "TRUVADA": 1.8230300634823915}
\ No newline at end of file
+{"COMIRNATY": 0.5086524299373673, "VAXZEVRIA": 4.276014323009033, "null": 0.6355693590279949}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8713.json
index a709904a94a..7ccd9efa1b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8713.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8713.json
@@ -1 +1 @@
-{"TOZINAMERAN": 1.484162810720565}
\ No newline at end of file
+{"COMIRNATY": 0.5903297215031792, "FENTANYL": 3.595361451805559, "KEYTRUDA": 3.268165081972396, "LEVOFLOXACIN": 4.116647049055191, "MEPOLIZUMAB": 4.298759269003549, "MIDAZOLAM": 11.045527286318029, "NUCALA": 3.529396839063053, "OPSUMIT": 6.124452527887295, "SPIKEVAX": 0.1678683403280517, "SYNAGIS": 11.07455627423752, "TOZINAMERAN": 0.902272048056072, "TRACLEER": 7.189704036274527, "TRELEGY": 7.57712623967994, "VAXZEVRIA": 0.2986867904254965, "null": 1.063673859791397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8714.json
index 8482c542480..708a79c7049 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8714.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8714.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2028406811223586}
\ No newline at end of file
+{"ABILIFY": 0.5529728532983007, "ACLIDINIUM": 1.239534732342454, "ADCIRCA": 14.281816804640364, "ADEMPAS": 9.6793301010186, "AFINITOR": 0.5991164427257717, "ALIMTA": 0.975161778905648, "AMBRISENTAN": 3.533309226435505, "ANORO": 1.6870789618726518, "APIDRA": 0.3505845492829939, "APIXABAN": 0.3635126534772204, "ARANESP": 0.2629046084675849, "ARAVA": 0.1433286392054021, "ASPARAGINASE": 0.6914203748108435, "ATOSIBAN": 4.236854980231739, "AUBAGIO": 0.2598326702070934, "AVAMYS": 0.8650288565954116, "AVASTIN": 0.9585875752474268, "BAVENCIO": 6.948554079882049, "BENLYSTA": 0.5486983158361116, "BENZODIAZEPINE": 1.9605803743559933, "BEVACIZUMAB": 0.6447110555282201, "BOSENTAN": 8.379300098464256, "BOSULIF": 0.9099572668817616, "BRIDION": 15.03968629781783, "BRIVARACETAM": 2.022583433238143, "BUDESONIDE": 0.9592395895169936, "BUPIVACAINE": 2.3645950727477967, "BUPRENORPHINE": 0.7030173992212201, "BUSULFAN": 0.4408692990157993, "BYETTA": 0.3573379839074947, "CAELYX": 1.9665946014951832, 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"PEMBROLIZUMAB": 0.6369949347438564, "PERJETA": 8.045774316196615, "PIRFENIDONE": 5.823649093624866, "PLAVIX": 0.2345949714455641, "POPPERS": 14.794796854259648, "PREGABALIN": 1.1571828966716555, "PRIVIGEN": 8.893965734234989, "QARZIBA": 3.4824606360539043, "RASBURICASE": 15.40879497277496, "RELVAR": 1.1295707087284534, "REMDESIVIR": 5.539009187792567, "REVATIO": 5.742038399604779, "RILUTEK": 4.895303902439751, "RINVOQ": 0.6222038290414894, "RITUXIMAB": 6.024550090277188, "RIVAROXABAN": 2.83420373383857, "RIXATHON": 10.307677812330326, "ROTATEQ": 0.4161381249209058, "SILDENAFIL": 5.8319674707231846, "SIMPONI": 0.1148315876953263, "SOLIRIS": 0.6284475450339386, "SPIKEVAX": 0.260671184458448, "SPINRAZA": 5.296458531195402, "STELARA": 0.2658295626167119, "STIVARGA": 0.2004078037130391, "SUBOXONE": 0.3787581005298857, "SUFENTANIL": 4.890130986763746, "SUTENT": 0.2117949919212849, "SYNAGIS": 8.98244744297829, "TAGRISSO": 0.9856032608898804, "TAMIFLU": 0.7601566767811878, "TOBI": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8715.json
index adc381421cf..e80f35170e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8715.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8715.json
@@ -1 +1 @@
-{"COVID19": 2.3885315379525798, "TOZINAMERAN": 2.645689076482844}
\ No newline at end of file
+{"null": 1.1356202846394847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8716.json
index 7d4d6cfa51f..7f16cb87e3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8716.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8716.json
@@ -1 +1 @@
-{"COVID19": 2.3061088247620534, "TOZINAMERAN": 2.640952684133594}
\ No newline at end of file
+{"IRBESARTAN": 128.9482607467275, "null": 0.776601708699106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8717.json
index 1b62d4c24a1..8c4b6960eeb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8717.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8717.json
@@ -1 +1 @@
-{"CICLOSPORIN": 38.273802464270375, "PEGASYS": 4.785999630580513}
\ No newline at end of file
+{"ANORO": 10.73050880517652, "AVANDIA": 8.30495392094646, "CELLCEPT": 3.7779321401899577, "COMIRNATY": 0.0689491288728092, "INCRUSE": 63.59037986865131, "KEYTRUDA": 4.168574062993439, "OPSUMIT": 13.124119840323823, "TRACLEER": 5.5005768303592655, "TRELEGY": 32.78922614320632, "null": 2.333719989521428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8718.json
index 93db632d73b..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8718.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8718.json
@@ -1 +1 @@
-{"HUMIRA": 249.33489495330292}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8719.json
index 671341c3905..8d84535eebe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8719.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8719.json
@@ -1 +1 @@
-{"ABATACEPT": 3.745452782178869, "ARAVA": 2.532275251851558, "ENBREL": 4.552206708749184, "RITUXIMAB": 8.74165906153246, "SOLIRIS": 6.560302115070571, "SPINRAZA": 18.891870948840715, "SYNAGIS": 14.998847410228054, "XELJANZ": 4.731834105090763}
\ No newline at end of file
+{"CELLCEPT": 554.5452355691326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/872.json
index 5d0240f1f50..9a87cf720d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/872.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/872.json
@@ -1 +1 @@
-{"ACLIDINIUM": 11.92723072463793, "ADENURIC": 13.099471940821651, "ALENDRONATE": 254.50821919849128, "APIXABAN": 22.964492168309945, "BIKTARVY": 15.761002625669224, "BUPIVACAINE": 7.875061063209982, "BYDUREON": 4.465037362524358, "BYETTA": 10.812551405395268, "CARBIDOPA": 14.13276579793092, "CLOPIDOGREL": 1.5018517184783098, "DARUNAVIR": 23.93434226255876, "ELIQUIS": 3.546436855125705, "ENTRESTO": 1.2473937069145522, "FORXIGA": 3.797803918459095, "ICLUSIG": 4.691031022613292, "JANUMET": 13.331830678936385, "JANUVIA": 11.983323802685156, "JARDIANCE": 2.6287490580911834, "KALETRA": 11.598803509844087, "TASIGNA": 2.055103741290894, "TOVIAZ": 24.31190126888239, "VIAGRA": 8.661753688545563, "ZOSTAVAX": 17.210155236675153, "ZYPREXA": 1.7589993821552494, "null": 1.0202175255248056}
\ No newline at end of file
+{"BAVENCIO": 11.55315777248286, "BENLYSTA": 1.7144877051950096, "BUDESONIDE": 0.5056197586216872, "CELLCEPT": 1.454811166515806, "CHAMPIX": 1.1484985792221722, "CIMZIA": 0.2822400575340497, "COMIRNATY": 1.012526678181051, "COSENTYX": 1.1556341144373057, "DESLORATADINE": 11.179078206059978, "DEXAMETHASONE": 0.5989677091040853, "ELIQUIS": 0.5216441615102433, "EXFORGE": 1.3869619490390417, "FORSTEO": 0.7042999065111701, "GARDASIL": 0.5026696838331964, "HUMALOG": 0.4387633214235572, "IBRANCE": 2.112369036849913, "INCRUSE": 4.973774797886219, "INLYTA": 12.147411688353444, "KEPPRA": 0.4368489798282532, "KEYTRUDA": 0.2838476286597249, "LANTUS": 0.3269642247232527, "METHOTREXATE": 1.0549471161915178, "MODERNA": 1.7625737430227169, "NEXAVAR": 0.4550463399491105, "NUCALA": 2.2644666948757504, "OMALIZUMAB": 3.3721099954938776, "OPSUMIT": 0.8514463787239035, "PEGASYS": 0.9668191851662676, "PEGINTRON": 1.2668058165840292, "RELVAR": 30.49818160930581, "REVINTY": 70.56324565898791, "SIMPONI": 1.1526005886836312, "SPIKEVAX": 0.5610823631824239, "STELARA": 0.5359115459088216, "STIVARGA": 2.55817137582958, "SUTENT": 0.8964455150084297, "TOVIAZ": 2.386394544325944, "TOZINAMERAN": 1.722255366237634, "TRELEGY": 8.242549318390695, "VAXZEVRIA": 0.556069699201273, "VOTRIENT": 1.363517335271768, "XELJANZ": 2.5103221883734976, "XOLAIR": 3.0061926110009853, "null": 1.339131060651208}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8720.json
index 755a1046a37..c6490dabd28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8720.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8720.json
@@ -1 +1 @@
-{"TESTOSTERONE": 929.6762637530966, "null": 1.2127354323898225}
\ No newline at end of file
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8721.json
index a6819683670..425edd19760 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8721.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8721.json
@@ -1 +1 @@
-{"ABACAVIR": 50.577737318825946, "ATAZANAVIR": 103.92412176085536, "ATRIPLA": 2.0640077732999016, "BARACLUDE": 56.15312567319019, "BIKTARVY": 29.66360819641498, "CABOTEGRAVIR": 308.41636702520475, "CELSENTRI": 42.95093565629815, "COMBIVIR": 7.704339649386891, "CYTARABINE": 1.808166912986361, "DACLATASVIR": 106.23972147270464, "DAKLINZA": 30.535854944315773, "DARUNAVIR": 137.44067924120804, "DESCOVY": 30.98274301988402, "DOLUTEGRAVIR": 213.4464445613229, "EFAVIRENZ": 100.4913544220476, "EMTRICITABINE": 55.0722778670858, "EMTRIVA": 45.5129816677031, "ENTECAVIR": 57.82476222836497, "EPCLUSA": 11.769276594698924, "EPIVIR": 7.575623127779882, "GENVOYA": 48.04037800029135, "HARVONI": 14.99916011346792, "HEPSERA": 12.064851630748649, "INCIVO": 5.280518751635785, "ISENTRESS": 14.332766554276567, "KALETRA": 4.068283849294812, "LAMIVUDINE": 70.34159354173681, "LOPINAVIR": 20.037287515319957, "NEVIRAPINE": 46.82189593573251, "OLYSIO": 12.010557119057042, "PEGASYS": 2.1131899223825954, "PEGINTERFERON": 15.943060221728189, "REKAMBYS": 251.4775160400662, "RIBAVIRIN": 62.376829354287736, "SOVALDI": 24.4060372416836, "STRIBILD": 8.415654762306158, "TIVICAY": 13.700562716154405, "TRIUMEQ": 16.189584049400146, "TRUVADA": 1.92480926905267, "VIREAD": 8.64454321459482, "ZEPATIER": 84.34085865790985}
\ No newline at end of file
+{"null": 0.9518920967503458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8722.json
index cc97d1bc055..a19f2124c58 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8722.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8722.json
@@ -1 +1 @@
-{"null": 2.203448711752774}
\ No newline at end of file
+{"COMIRNATY": 0.1253222930908771, "null": 2.867673762763612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8723.json
index 90b88b2dc55..1c39032eb2e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8723.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8723.json
@@ -1 +1 @@
-{"CICLOSPORIN": 35.85207887738773}
\ No newline at end of file
+{"FENTANYL": 22.13776653390361, "HYDROCORTISONE": 29.482577194220813, "MIDAZOLAM": 88.87676237242174, "null": 1.8432035329484344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8724.json
index 752d9e92b2b..91f607b2cac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8724.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8724.json
@@ -1 +1 @@
-{"null": 2.792889305099717}
\ No newline at end of file
+{"null": 1.7549413295032312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8725.json
index 9bad6cfdc34..287ef0bf374 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8725.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8725.json
@@ -1 +1 @@
-{"COMIRNATY": 1.0965730475731472}
\ No newline at end of file
+{"LATUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8726.json
index 84a20c8d05c..e8c202cc39f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8726.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8726.json
@@ -1 +1 @@
-{"COVID19": 6.880848315192607, "VAXZEVRIA": 5.174917890030904}
\ No newline at end of file
+{"ALPELISIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8727.json
index bb0f10b430d..d94dd900482 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8727.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8727.json
@@ -1 +1 @@
-{"null": 1.7106632264816388}
\ No newline at end of file
+{"ABRAXANE": 384.2762242630757, "AFINITOR": 39.18949146316312, "CAPECITABINE": 125.05764910487795, "EVEROLIMUS": 320.8386037988223, "FULVESTRANT": 127.9572508703418, "RIBOCICLIB": 139.72286085065116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8728.json
index f981bf9ed63..5c9df36d017 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8728.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8728.json
@@ -1 +1 @@
-{"ABILIFY": 1.193760349563994, "ACTOS": 1.5982255071074565, "ADENURIC": 1.1145956969003643, "ANORO": 1.4175096031904315, "APIDRA": 2.571685654584165, "AUBAGIO": 1.5603005848434488, "AZOPT": 4.478210695257494, "BEOVU": 23.60616258017804, "BETMIGA": 1.1580888356164871, "BINIMETINIB": 2.65054032262972, "BRAFTOVI": 3.574438113771456, "BRIMONIDINE": 4.520321914987699, "BRINTELLIX": 1.496254760080328, "BRIVIACT": 1.5936325138123004, "BROLUCIZUMAB": 18.03831414607306, "CHAMPIX": 1.60021587640464, "CIALIS": 1.6796245478859766, "CIRCADIN": 2.474553016854664, "COAPROVEL": 1.5107209247158695, "COMIRNATY": 1.0101058244170622, "COVID19": 1.4601065848972974, "CYMBALTA": 1.313500333005386, "DAKLINZA": 1.0841923618368656, "DULAGLUTIDE": 1.200602875810177, "ENTYVIO": 1.518843830313302, "EXFORGE": 1.0270541518082177, "EXJADE": 1.123005170789963, "EYLEA": 12.0628530028303, "GALVUS": 1.0580372512945573, "GARDASIL": 2.0010283589405917, "GILENYA": 2.3574777980921424, "GLIBENCLAMIDE": 1.3352960481887597, "HUMALOG": 1.6938680783245124, "HYDROCHLOROTHIAZIDE": 2.686706493226288, "IKERVIS": 6.614781387406226, "INCRUSE": 2.329794543574881, "INSULIN": 1.4994566843393606, "INVEGA": 1.2932474496558284, "JETREA": 19.493050935978797, "KENTERA": 4.3785248553856, "LANTUS": 2.247417440345172, "LATUDA": 1.1698313663534865, "LEVEMIR": 1.0035918502019725, "LEVITRA": 8.44443590716779, "LUCENTIS": 4.530590928327984, "LUXTURNA": 8.636445954402651, "LYRICA": 2.458921802057494, "MEKINIST": 2.208958882173063, "MEPOLIZUMAB": 1.0863170165271785, "MIRCERA": 1.004360582073876, "NEVANAC": 15.640708182897498, "ONGLYZA": 1.003350540453955, "OPATANOL": 10.786548381990274, "OXYBUTYNIN": 3.2258182651922938, "OZEMPIC": 1.0931747320481895, "PEGASYS": 2.05337653587614, "PEGINTRON": 1.712035005195661, "POPPERS": 5.002092310136744, "PREGABALIN": 1.3498379179117936, "RANEXA": 4.3750695015231225, "REAGILA": 5.436173658770063, "RELVAR": 2.0795925226371463, "REVINTY": 5.499932006837014, "RYBELSUS": 1.1471167194401892, "SIFROL": 1.47878227242208, "SILDENAFIL": 2.6986618795781907, "SYCREST": 1.1768199802447432, "TAFINLAR": 1.683645361773983, "TAGRISSO": 1.1138829579095617, "TOUJEO": 1.5077511338510043, "TOVIAZ": 4.571683440713003, "TOZINAMERAN": 1.7868838640682372, "TRELEGY": 2.6769159722382745, "UMECLIDINIUM": 1.8349837782561376, "UROREC": 2.223952833161028, "VARENICLINE": 1.6035136818969205, "VAXZEVRIA": 1.0484768254726284, "VFEND": 6.3972850685998495, "VIAGRA": 4.441704833258853, "VIMPAT": 2.6483250451990625, "VORICONAZOLE": 3.728147057338634, "XALKORI": 1.6020461816216338, "XTANDI": 1.2168147581254185, "ZELBORAF": 1.3530733706432838, "ZYPREXA": 1.1201055736251222, "null": 1.1184921324752448}
\ No newline at end of file
+{"AZATHIOPRINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8729.json
index fd2dd636540..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8729.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8729.json
@@ -1 +1 @@
-{"AFLIBERCEPT": 23.507422507729093, "AVAMYS": 1.6347717898255416, "AVASTIN": 3.7106504056524, "AZOPT": 16.361061148031908, "BELANTAMAB": 74.72834515800422, "BEOVU": 148.50758408819283, "BETAFERON": 1.893306650745608, "BLENREP": 316.1880632821686, "BRAFTOVI": 2.335364373805172, "BROLUCIZUMAB": 129.35655425693488, "BYDUREON": 1.1839779724848332, "CELLCEPT": 1.2288379166216812, "CICLOSPORIN": 1.8916861546053412, "COMBIVIR": 2.0797661191021044, "DARZALEX": 1.2625991529655611, "DEXAMETHASONE": 2.2924034765118444, "EVISTA": 2.390287140205289, "EXJADE": 1.0771037860012322, "EYLEA": 106.82419652228845, "FLORAJEN": 336.0945697421141, "GARDASIL": 1.1155896939708252, "HUMALOG": 2.261790204874336, "INTRONA": 2.6690351352316832, "JETREA": 313.8552977799534, "LAMIVUDINE": 2.25264336248127, "LANTUS": 1.7496793481308777, "LUCENTIS": 38.290648912713706, "MEKINIST": 2.6044406314163044, "MYCOPHENOLATE": 3.874615816425727, "NEPAFENAC": 76.68996211924863, "NEVANAC": 32.78119662924404, "PEGASYS": 1.5510442022647553, "PEGINTERFERON": 2.4734504262372723, "PEGINTRON": 2.2511329986056112, "REBETOL": 3.059559508233645, "REVATIO": 1.699403635468253, "SILDENAFIL": 3.8887951264231178, "TASIGNA": 1.151221621794255, "TOBRAMYCIN": 5.19426476495989, "TOVIAZ": 1.288125381756111, "TWINRIX": 1.4546000061636737, "VFEND": 5.0568752964547246, "VIAGRA": 5.984875990811678, "VIGABATRIN": 16.361061148031908, "VORICONAZOLE": 1.5335627576169846, "null": 1.2763650391623769}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/873.json
index 5aede1776f4..f20c66b7728 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/873.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/873.json
@@ -1 +1 @@
-{"null": 1.861941127541158}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8730.json
index 362915efe0a..1910457743d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8730.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8730.json
@@ -1 +1 @@
-{"EYLEA": 205.06829786600085, "JETREA": 569.8555452218397, "null": 2.5818766842578027}
\ No newline at end of file
+{"null": 0.8074973192244699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8731.json
index 6992c4dea11..a5a0b93e3e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8731.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8731.json
@@ -1 +1 @@
-{"null": 1.5030322087711956}
\ No newline at end of file
+{"COMIRNATY": 0.2390339386062151, "DEXAMETHASONE": 4.782488350031504, "FENTANYL": 7.280084959006798, "HYDROCORTISONE": 19.89671380790012, "null": 2.3131399007571503}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8732.json
index 08bbfd763d6..97aa9f70e89 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8732.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8732.json
@@ -1 +1 @@
-{"VFEND": 37.90209187304908, "VIAGRA": 84.09992242207515}
\ No newline at end of file
+{"MIDAZOLAM": 67.08114236444877, "null": 1.9403373476145716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8733.json
index 36aec79d8ca..d35bfdc6812 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8733.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8733.json
@@ -1 +1 @@
-{"AIMOVIG": 3.68479689295694, "AUBAGIO": 1.3376487928884324, "AVASTIN": 1.386697128109159, "BEOVU": 17.971020566661668, "BOTULINUM": 5.700475956517559, "CHAMPIX": 1.276995223653031, "COMBIVIR": 3.154701654509358, "EVISTA": 2.70299387428394, "EXFORGE": 1.659259673490216, "EYLEA": 9.664499307605578, "GARDASIL": 1.4817232055708562, "HUMALOG": 1.4188853699095665, "INTRONA": 4.859648416242328, "JETREA": 77.33559571568176, "KEPPRA": 1.2323870371434362, "MEKINIST": 1.9060641431068572, "PEGASYS": 1.1001326515195886, "PEGINTRON": 5.325001982935796, "REVATIO": 1.6441894864725275, "SILDENAFIL": 5.638836987703472, "TASIGNA": 1.2462919310227885, "TWINRIX": 3.5164589069405845, "VFEND": 4.902048195383463, "VIAGRA": 18.87157777445864, "VIGABATRIN": 386.7798912250898, "VOTRIENT": 1.0126300721196293, "null": 1.7349080522520586}
\ No newline at end of file
+{"FILGRASTIM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8734.json
index 05acb37a673..ab84ba4a0b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8734.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8734.json
@@ -1 +1 @@
-{"null": 1.1820190577204712}
\ No newline at end of file
+{"IRINOTECAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8735.json
index 85a236634b9..446c817514a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8735.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8735.json
@@ -1 +1 @@
-{"ABASAGLAR": 3.506080805167576, "AIMOVIG": 1.0378969936082632, "ALL": 1.025639118805382, "APIDRA": 4.656397479508501, "APROVEL": 1.342278076683764, "AUBAGIO": 2.446971027120906, "AVAMYS": 1.09014624738783, "AVASTIN": 1.226557530815077, "AZOPT": 5.181402587196589, "BELANTAMAB": 14.39819922915318, "BEOVU": 15.303544586473242, "BETAFERON": 1.1971475748915794, "BETMIGA": 1.452601190223533, "BINIMETINIB": 1.9732014930879025, "BLINCYTO": 2.485637782188793, "BRAFTOVI": 3.2075703988200104, "BRINTELLIX": 1.1022631718850695, "BROLUCIZUMAB": 17.66306922815562, "BYDUREON": 1.2484435189463812, "CIALIS": 1.4868229586704114, "COMIRNATY": 1.0437804685956362, "COTELLIC": 1.3517699903782103, "CYMBALTA": 1.154382750460868, "DAKLINZA": 1.1462962544334454, "DELTYBA": 3.6410359803174464, "DRONEDARONE": 9.381421933072788, "DULAGLUTIDE": 3.26031759834686, "EVISTA": 1.71660726689511, "EVOLOCUMAB": 12.488085687630624, "EXFORGE": 1.715797671909661, "EXJADE": 1.0465407431514568, "EYLEA": 15.071782429343443, "FIRDAPSE": 1.1033904548715947, "GARDASIL": 1.9127214936288308, "GILENYA": 2.2612639621503563, "GLIBENCLAMIDE": 1.0532421662785143, "HUMALOG": 6.828254123474561, "IBRANCE": 1.1353721141763808, "IKERVIS": 5.959429557153886, "INCRUSE": 1.3221362304644335, "INSULIN": 2.7469159900887696, "INSUMAN": 1.5410327906411896, "JCOVDEN": 2.5679817323795118, "JETREA": 27.21344601221359, "KESIMPTA": 1.4412028543543771, "LANTUS": 8.79495953480712, "LEVEMIR": 1.5391165471875152, "LIXIANA": 1.564351291682485, "LUCENTIS": 5.673552456338943, "LUXTURNA": 15.390855893424083, "LYRICA": 1.063929448749659, "MEKINIST": 3.3629855414440617, "MELATONIN": 1.399718896858676, "NEVANAC": 9.143000338439425, "OPATANOL": 5.85637179482383, "PEGASYS": 1.0740087380333678, "PEGINTRON": 1.603139546286778, "PLEGRIDY": 1.354379911431863, "RANEXA": 2.260566440901425, "REVATIO": 1.7421634465108602, "RYBELSUS": 1.1454981380823914, "SIFROL": 1.3038221521615914, "SILDENAFIL": 1.9581997176170176, "TAFINLAR": 1.419254859674084, "TERIFLUNOMIDE": 1.4170933759625124, "THIOTEPA": 6.677342690487749, "TIKOSYN": 3.519889071561064, "TOUJEO": 5.016017648068181, "TOVIAZ": 1.7529392887811572, "TRELEGY": 1.2972385971451783, "TRULICITY": 1.1352288732494615, "TWINRIX": 1.9943872264668543, "UROREC": 1.675633739548722, "VFEND": 8.021913558434237, "VIAGRA": 4.79238179223219, "VIGABATRIN": 1.7807420489098682, "VORICONAZOLE": 4.336999119729569, "XALKORI": 5.382014105059722, "XELJANZ": 1.0888902665646354, "null": 1.1136876410793728}
\ No newline at end of file
+{"null": 0.9536240008229327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8736.json
index 655502d1e07..02fedb6a806 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8736.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8736.json
@@ -1 +1 @@
-{"null": 1.6549644704186128}
\ No newline at end of file
+{"null": 1.9460428011436304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8737.json
index 6eaf5518853..3abf6491086 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8737.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8737.json
@@ -1 +1 @@
-{"null": 3.3530131450886724}
\ No newline at end of file
+{"COMIRNATY": 0.7305606708065345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8738.json
index 76221d7e185..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8738.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8738.json
@@ -1 +1 @@
-{"COMIRNATY": 1.417786558295303, "TOZINAMERAN": 3.5446272312075773, "null": 1.0627143682246851}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8739.json
index 97fa1a826f2..dca3aea6792 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8739.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8739.json
@@ -1 +1 @@
-{"null": 2.8888362465479496}
\ No newline at end of file
+{"null": 2.5442359161660035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/874.json
index e21cb7522a7..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/874.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/874.json
@@ -1 +1 @@
-{"null": 1.6524088228168026}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8740.json
index 2bffbc4fe36..048f42cf349 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8740.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8740.json
@@ -1 +1 @@
-{"null": 6.133797719085272}
\ No newline at end of file
+{"null": 2.2434296420663644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8741.json
index 65c3bc1c98e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8741.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8741.json
@@ -1 +1 @@
-{"ACLIDINIUM": 92.33591239843228, "AVAMYS": 33.708023149884795, "BUDESONIDE": 36.50840408520065, "MEPOLIZUMAB": 33.828378393225535, "NUCALA": 37.23038751428189, "SPINRAZA": 66.0556316173409}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8742.json
index 7b9a914e041..371703f457b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8742.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8742.json
@@ -1 +1 @@
-{"null": 3.615082672656949}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8743.json
index 6e38d8a1143..87ea81e3e7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8743.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8743.json
@@ -1 +1 @@
-{"SOMAVERT": 721.8178136516517, "null": 1.0892773441284185}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8744.json
index 836efe08cd3..5eec70cd219 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8744.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8744.json
@@ -1 +1 @@
-{"KAFTRIO": 1523.9929785452157}
\ No newline at end of file
+{"ABATACEPT": 0.6642188025105343, "ABILIFY": 0.484979122715147, "ADALIMUMAB": 0.4585718679748109, "ADCIRCA": 22.686402456831495, "ADEMPAS": 33.97084848612666, "AFINITOR": 1.042019870981084, "AIMOVIG": 0.6093056101997236, "AMBRISENTAN": 20.35193601894708, "ARAVA": 0.1292207272769728, "ATRIPLA": 0.0681843849791038, "AUBAGIO": 0.6746598134094758, "AZATHIOPRINE": 1.4824646845830214, "BENLYSTA": 0.5592994881835333, "BONVIVA": 12.582461971561989, "BRINTELLIX": 0.9581441589670632, "BYDUREON": 0.5635969974521204, "CHAMPIX": 0.6295678981222365, "CICLOSPORIN": 0.4669980563441802, "CIMZIA": 0.1549163324167751, "COMIRNATY": 1.2790598295992306, "COSENTYX": 0.703722427485598, "CYMBALTA": 0.6595150406007526, "CYTARABINE": 1.127302771837804, "ELIQUIS": 0.1575207386778227, "ENBREL": 1.3033109353416137, "EVENITY": 3.2613983174053947, "FASLODEX": 1.7685651732015455, "FORSTEO": 2.558108499960419, "GARDASIL": 1.1342688711321702, "HUMALOG": 0.1942494464078364, "HUMIRA": 1.579578642070909, "IBRANCE": 0.9260270497092672, "IBUPROFEN": 1.043071619010072, "JARDIANCE": 0.2541337383819112, "KEYTRUDA": 0.2840360294927218, "LATUDA": 0.8607211440638327, "MACITENTAN": 17.58210848648869, "METHOTREXATE": 0.7260868240849311, "OCRELIZUMAB": 1.7284067872887314, "OMALIZUMAB": 0.6905420209131177, "OPSUMIT": 18.82712836144791, "OPTIMARK": 0.5230453038362096, "PEGASYS": 0.4103710209441202, "PLAVIX": 0.2578260413278513, "REVATIO": 3.0770392163178446, "ROACTEMRA": 0.8770870024473977, "SHINGRIX": 0.7636697767719466, "SILDENAFIL": 9.43061971669005, "SIMPONI": 0.5553446766652768, "SPIKEVAX": 1.1010651851307036, "STELARA": 0.7545592969339356, "SUNITINIB": 8.918078838186114, "SUTENT": 1.618165559098256, "TOZINAMERAN": 2.7484564371496187, "TRACLEER": 4.122891400100203, "UPTRAVI": 36.72165043494049, "VAXZEVRIA": 1.476676062028509, "XELJANZ": 0.6261804348675548, "XOLAIR": 0.4147752153953315, "ZOMETA": 9.804681688608202, "ZOSTAVAX": 0.7066284040600317, "null": 0.7071078262223807}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8745.json
index ff6a4450ffd..313a8a66b99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8745.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8745.json
@@ -1 +1 @@
-{"ZOSTAVAX": 11.323003200017338}
\ No newline at end of file
+{"null": 0.7011289212253213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8746.json
index 1d208834784..1e2a5d89862 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8746.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8746.json
@@ -1 +1 @@
-{"null": 2.218024882384535}
\ No newline at end of file
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8747.json
index d9bece350bb..939d0ebe371 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8747.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8747.json
@@ -1 +1 @@
-{"null": 1.200723225209131}
\ No newline at end of file
+{"HERCEPTIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8748.json
index 727359e1fb4..2a2cee57dda 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8748.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8748.json
@@ -1 +1 @@
-{"CARBIDOPA": 228.5587609378844, "CELECOXIB": 34.9094075788953, "EMPAGLIFLOZIN": 42.3645271281246, "IBRANCE": 2.8129774346695293, "JANUMET": 5.420318170587345, "JANUVIA": 5.524205912729828, "PANTOPRAZOLE": 36.46712627755692, "SUTENT": 1.818566748131044, "null": 1.0640017258177306}
\ No newline at end of file
+{"SUBOXONE": 165.48324128422408, "null": 0.4441435893871593}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8749.json
index 716a96a9145..244c49a522d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8749.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8749.json
@@ -1 +1 @@
-{"AIMOVIG": 1.828229448699412, "APREPITANT": 48.45176838222381, "ARANESP": 3.036715902304327, "BUPRENORPHINE": 6.258006334091199, "COSENTYX": 1.3863569899360355, "ESOMEPRAZOLE": 11.927802543359984, "GARDASIL": 2.192588415701701, "IBRANCE": 1.636919374825676, "LYRICA": 3.3800254127095326, "PANTOPRAZOLE": 14.746295557780602, "STELARA": 1.5142218777294476, "ZOSTAVAX": 10.579272743312004, "null": 1.3682445534148644}
\ No newline at end of file
+{"LEVOFLOXACIN": 53.03259614056082, "null": 3.573817623195848}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/875.json
index 64447fb8e5a..77fe4ce3262 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/875.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/875.json
@@ -1 +1 @@
-{"null": 2.8246314187502346}
\ No newline at end of file
+{"null": 8.802191536399585}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8750.json
index 9d48c32fc67..e6e46c8788e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8750.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8750.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 52.63814127375192}
\ No newline at end of file
+{"OLANZAPINE": 25.291241206496277, "VIAGRA": 481.4038272174812, "null": 0.7379100413294987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8751.json
index 3505de985b2..5a7d9a741f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8751.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8751.json
@@ -1 +1 @@
-{"INTELENCE": 853.9363846056168, "MIRABEGRON": 1151.6607132013544}
\ No newline at end of file
+{"BENLYSTA": 2.9166157572853675, "COMIRNATY": 2.980801924218376, "ESBRIET": 3.9195451110955695, "SPIKEVAX": 2.283196275860032, "TAMIFLU": 2.9870078531201028, "TOZINAMERAN": 3.153248915916329, "VAXZEVRIA": 1.0369416141933734, "XELJANZ": 1.2224953256440092, "null": 0.4064888214515801}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8752.json
index 669a6d2f194..0d99dbad887 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8752.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8752.json
@@ -1 +1 @@
-{"null": 2.397730974771322}
\ No newline at end of file
+{"COMIRNATY": 0.3619458124132262, "VAXZEVRIA": 0.2904172908426994, "null": 1.831664878361748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8753.json
index 4abd33b5941..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8753.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8753.json
@@ -1 +1 @@
-{"ORENCIA": 2771.332428029834}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8754.json
index d7df27f5177..04c22dcc569 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8754.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8754.json
@@ -1 +1 @@
-{"ACLASTA": 53.85487049570725, "AMBRISENTAN": 24.229767969928343, "ANAKINRA": 17.13515439897042, "ATRIPLA": 2.876135009724897, "AUBAGIO": 2.46930631740422, "CARIPRAZINE": 125.5708508860112, "CELECOXIB": 8.096134432081547, "CYMBALTA": 2.991942822434851, "ELIQUIS": 1.4245947944911237, "FORSTEO": 9.45027254818665, "GARDASIL": 2.600567244642193, "HUMIRA": 2.649990869289151, "IBRANCE": 1.7263732443723627, "KEPPRA": 1.3982993663700105, "LANTUS": 1.038195931884176, "LYRICA": 3.0119838845911846, "ORENCIA": 49.84455832493192, "PEGASYS": 1.0507416564531409, "RINVOQ": 4.118669329111923, "STRIBILD": 5.153770237075881, "SUTENT": 1.356924828834122, "TRUVADA": 1.0916605772820815, "XELJANZ": 3.325154002157109, "ZOSTAVAX": 3.741944628578685, "null": 1.1481589982827038}
\ No newline at end of file
+{"COMIRNATY": 0.8493066300651532, "FENTANYL": 2.316422998822548, "LEVOFLOXACIN": 2.9390988665922104, "SPIKEVAX": 0.1873633450206062, "VAXZEVRIA": 0.1537568343259847, "null": 4.287269530594615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8755.json
index 2dd1d0aab33..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8755.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8755.json
@@ -1 +1 @@
-{"ATRIPLA": 52.40866713315488, "BIKTARVY": 1.985791340321757, "BUPRENORPHINE": 1.08135018737818, "ENBREL": 1.8722252421174552, "EPADERM": 131.92898654040428, "FAMPYRA": 5.138622143529631, "FORSTEO": 1.2164865533776144, "GARDASIL": 1.3047421717118692, "HUMALOG": 1.5761896415786731, "JANUMET": 1.337815733549576, "LYRICA": 1.2081557369859168, "METFORMIN": 12.499801468984623, "STRIBILD": 14.623116481880254, "TRUVADA": 16.546395533804326, "VIREAD": 5.256331873717271, "ZOSTAVAX": 10.43365847233664}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8756.json
index 2cf55a9d87e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8756.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8756.json
@@ -1 +1 @@
-{"FORSTEO": 20.14436392433228, "null": 1.2320921777283136}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8757.json
index c94337e911c..72595f6f000 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8757.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8757.json
@@ -1 +1 @@
-{"null": 2.4674108568917084}
\ No newline at end of file
+{"COMIRNATY": 1.6064442250454605, "SPIKEVAX": 0.9327507763674732, "TOZINAMERAN": 0.8857316474888371, "VAXZEVRIA": 0.7445152509255416, "null": 1.2715507561828816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8758.json
index 73421f1ada9..2e80d64e5ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8758.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8758.json
@@ -1 +1 @@
-{"null": 6.946393816732602}
\ No newline at end of file
+{"null": 0.6156577272746339}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8759.json
index 1b75988447a..2e5aee77245 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8759.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8759.json
@@ -1 +1 @@
-{"null": 2.2503218089250407}
\ No newline at end of file
+{"COMIRNATY": 1.0131110683789606, "ENBREL": 30.56085376519544, "VAXZEVRIA": 0.7602800408351843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/876.json
index 7efa8018aa3..c9d8a1b8b8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/876.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/876.json
@@ -1 +1 @@
-{"null": 3.5148518229747605}
\ No newline at end of file
+{"ALEMTUZUMAB": 9.68095552912131, "APROVEL": 3.8706485737598055, "ARANESP": 171.85716537242172, "ATRIPLA": 0.1050739383442552, "BINOCRIT": 172.36431590406747, "BUSULFAN": 3.159338702518597, "CELLCEPT": 12.241267496766191, "CICLOSPORIN": 4.117237124490844, "COMBIVIR": 5.211683537367236, "DARBEPOETIN": 26.41592018628307, "EMTRIVA": 18.74988426690793, "EPOETIN": 210.8803792217742, "EXJADE": 1.3550021494853917, "IPILIMUMAB": 2.784467066528548, "KEPPRA": 0.6887157524473674, "KEYTRUDA": 1.0621180017740517, "LYRICA": 1.1064656443027925, "MIRCERA": 245.8315059291889, "MYCOPHENOLATE": 9.399504414378557, "NEORECORMON": 473.508449493159, "OPDIVO": 1.144019940637858, "PEGASYS": 2.114870246685556, "PEGINTERFERON": 7.73264308463609, "PEGINTRON": 6.453376607821674, "RIBAVIRIN": 27.072688433532356, "TACROLIMUS": 9.435409341152765, "null": 1.1295147253177915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8760.json
index 0b354576b80..b51be9ffe77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8760.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8760.json
@@ -1 +1 @@
-{"ALDARA": 31.379429357719623, "AZATHIOPRINE": 3.60662459649064, "BRAFTOVI": 5.381217776298687, "CICLOSPORIN": 1.8373044704651749, "COSENTYX": 4.257702294001496, "ETANERCEPT": 46.50624058279444, "IPILIMUMAB": 112.66543173819584, "KEYTRUDA": 19.69859570869667, "KISQALI": 35.761569876368, "LEMTRADA": 11.13938739947966, "MEKINIST": 5.293387619662759, "NEOFORDEX": 830.8278739549502, "OPDIVO": 11.99276302293395, "PEGASYS": 1.5756351722208046, "PEMBROLIZUMAB": 44.42715331401061, "RIBOCICLIB": 31.45282931179806, "STELARA": 9.276179696745574, "XOLAIR": 1.6312759102483432, "YERVOY": 30.315521759509934}
\ No newline at end of file
+{"KEYTRUDA": 6.598778109954676, "OPSUMIT": 12.553640202443075, "VOTRIENT": 25.405691378746152, "null": 1.0099064913253375}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8761.json
index 002362e5ba7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8761.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8761.json
@@ -1 +1 @@
-{"BEOVU": 1187.2914145958564, "EYLEA": 605.7617790476562}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8762.json
index 97d85c82ceb..c69f46a884c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8762.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8762.json
@@ -1 +1 @@
-{"EYLEA": 2302.320212729981}
\ No newline at end of file
+{"ABILIFY": 0.2208140795706211, "AERIUS": 1.390667981295004, "AFINITOR": 0.4739603424893831, "AIMOVIG": 0.1980413813171333, "AMIKACIN": 1.0278921246086536, "AMINOSALICYLIC": 0.4005950185077889, "APIDRA": 0.7374815414149578, "APIXABAN": 0.4071990718091149, "ARANESP": 0.2092706025082093, "ARAVA": 0.0618817063385519, "AUBAGIO": 0.1907985465142223, "AVANDIA": 0.2154375384803216, "AVASTIN": 0.4695493393628313, "BENLYSTA": 0.4281714616472091, "BEXSERO": 14.181942130033738, "BUDESONIDE": 0.4355500925308688, "BUPIVACAINE": 1.2554749723217171, "BUPRENORPHINE": 0.3579404820235965, "BYETTA": 0.3312985485947279, "CANNABIDIOL": 3.392184079839612, "CASPOFUNGIN": 3.7838664790241543, "CELLCEPT": 0.2895114603485557, "CERVARIX": 6.86859452243747, "CHAMPIX": 0.7438681989265687, "CICLOSPORIN": 0.3729700079012322, "CLOPIDOGREL": 2.536530659593345, "COAPROVEL": 1.090668918645285, "COMBIVIR": 2.710359958251447, "COMIRNATY": 0.9830210451117468, "COSENTYX": 0.5339414551842165, "CYMBALTA": 0.1690617111273299, "CYTARABINE": 1.3378056742173676, "DEXAMETHASONE": 0.6536388610988906, "DIPHTHERIA": 89.76067702034715, "DOCETAXEL": 0.6040021942991053, "DULOXETINE": 0.5106148435558062, "EFAVIRENZ": 1.160056343748703, "ELIQUIS": 0.4689449191704483, "ENOXAPARIN": 1.9258077837075944, "ENTRESTO": 0.3455380394951808, "ENTYVIO": 0.5874573494142927, "EXFORGE": 0.5578748681514862, "EXJADE": 0.9811078578316134, "FASLODEX": 0.2958085056001085, "FENTANYL": 0.8840771328599317, "FLEBOGAMMA": 6.84359092637822, "FORSTEO": 0.3742761003034359, "GALVUS": 0.930462355543732, "GANCICLOVIR": 0.9006716936060091, "GARDASIL": 9.187659073919349, "HEXYON": 13.750865198494292, "HIZENTRA": 0.6946905172363322, "HUMALOG": 0.5137995566177125, "HUMAN": 1.265764930388043, "HYDROCORTISONE": 0.8048552059892519, "IBRANCE": 0.0925815157386036, "IBUPROFEN": 0.9852483312931118, "INFANRIX": 16.248024420691035, "INSULIN": 0.7616027009410345, "IRON": 2.475175532476021, "ISCOVER": 4.492885612179072, "JAKAVI": 1.0537383436793923, "JARDIANCE": 0.2452263455617536, "KEPPRA": 0.3230930491979993, "KEYTRUDA": 0.1496012404654285, "KIOVIG": 3.765217042152922, "LAMIVUDINE": 2.711199273099341, "LANTUS": 1.0827531068819722, "LEVETIRACETAM": 0.2735630291086601, "LEVOFLOXACIN": 0.3770748408747009, "LIXIANA": 0.9584301374173986, "MENVEO": 10.72615151737391, "MEPOLIZUMAB": 0.2261606962978752, "MERCAPTOPURINE": 2.59762019533, "METHOTREXATE": 0.2415526460517606, "MICARDIS": 0.4935418951069635, "MIXTARD": 3.9617418968492, "MMRVAXPRO": 5.936928193112712, "NAGLAZYME": 7.544964086616661, "NEXAVAR": 0.1137349352030292, "NIMENRIX": 8.120515377750237, "NOT": 3.716890169333408, "NOVORAPID": 0.3046701704171886, "NPLATE": 0.5238204663305261, "OLANZAPINE": 0.485568083718748, "OMALIZUMAB": 0.4083186262298481, "ONCASPAR": 4.6777644530414975, "OPSUMIT": 0.8281059424670478, "PANTOPRAZOLE": 0.7043558924203981, "PEGASYS": 0.9599684507776246, "PEGINTERFERON": 1.050668957203724, "PEGINTRON": 0.8995199131102429, "PLAVIX": 0.8960290244656999, "PREGABALIN": 2.026242357843714, "PREVENAR": 15.10468510102677, "PRIVIGEN": 2.6521102559687644, "RENVELA": 55.625400002667504, "RIBAVIRIN": 0.593933277202989, "RITUXIMAB": 0.2356220412497546, "ROACTEMRA": 0.7751301284278119, "ROTARIX": 31.686440174265208, "ROTATEQ": 10.182861199158278, "SAXENDA": 0.3312169855500765, "SHINGRIX": 0.327452050426455, "SOLIRIS": 0.8342964204855036, "SPIKEVAX": 0.6402029808413152, "SPINRAZA": 0.647516443891112, "STELARA": 0.1604052456848703, "SUBOXONE": 0.286992545879847, "SUTENT": 1.1587730465788235, "SYNAGIS": 5.311443554115138, "TAMIFLU": 1.0581851167181475, "TASIGNA": 0.7180005110774311, "TICAGRELOR": 1.6778391655529554, "TOZINAMERAN": 1.4346941282857386, "TRACLEER": 0.7035490700149918, "TREMFYA": 0.661931437630045, "TWINRIX": 4.48774744077712, "VAXZEVRIA": 0.5029707326502469, "VIAGRA": 0.4582122927301759, "VIMPAT": 0.4990820980421429, "VOTRIENT": 0.7291646605757939, "XELJANZ": 0.0759496258883862, "XOLAIR": 1.0438003167876997, "XTANDI": 0.1806729069952367, "ZOSTAVAX": 0.2577985099246949, "ZYPADHERA": 4.007920658462364, "ZYPREXA": 0.3366039799166799, "null": 1.5669001577678154}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8763.json
index d34bcaaf2dc..a9b2191a787 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8763.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8763.json
@@ -1 +1 @@
-{"ZOSTAVAX": 68.902158181046}
\ No newline at end of file
+{"COMIRNATY": 0.4720057274737356, "MANNITOL": 133.11433221108734, "NEXAVAR": 8.540918636972627, "SPIKEVAX": 0.2529166825510013, "SUTENT": 4.191795325553512, "TOZINAMERAN": 0.4442261161805684, "VAXZEVRIA": 0.2142486406080103, "null": 2.0004250996046435}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8764.json
index 4233b4cab33..bea923dc570 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8764.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8764.json
@@ -1 +1 @@
-{"AVASTIN": 6.367057047321531, "BEOVU": 48.30570463289322, "COMIRNATY": 1.461355973872044, "COVID19": 1.1323015116712998, "EYLEA": 28.306901436128783, "PEGASYS": 1.017047569885857, "STELARA": 1.8827192735064329, "TOZINAMERAN": 1.759083697644204, "VAXZEVRIA": 1.2520615495988243, "VIAGRA": 9.086964720024444, "VOTRIENT": 3.008657789062193, "ZOSTAVAX": 17.27819071894264}
\ No newline at end of file
+{"ABRAXANE": 3.692960490420063, "AFINITOR": 2.9565749695968706, "ALIMTA": 0.4305185384726954, "ALOXI": 13.355275236298018, "AVASTIN": 8.24137452389772, "AVELUMAB": 4.649060618661651, "AXITINIB": 21.530351283519924, "BAVENCIO": 24.120606528277506, "BEVACIZUMAB": 8.14556043523715, "BRAFTOVI": 2.154090941186156, "BUSULFAN": 1.420947651965323, "CABOMETYX": 62.657843755032495, "CABOZANTINIB": 27.602612950673223, "CAELYX": 58.44418964901055, "CAPECITABINE": 18.68923197649776, "CETUXIMAB": 3.2096717802750594, "CLOFARABINE": 9.674008355036984, "COMIRNATY": 0.0078898304127336, "COTELLIC": 1.2232503797355063, "CYTARABINE": 0.800131130754209, "DEXAMETHASONE": 0.514719641453111, "DOCETAXEL": 4.537346373477682, "DOXORUBICIN": 1.968713595412756, "ERBITUX": 4.934282183697775, "ERLOTINIB": 13.580746876506206, "EVEROLIMUS": 7.692662760600868, "FASLODEX": 0.4579910447393237, "FOTIVDA": 21.99549428320448, "FULVESTRANT": 0.9172960606911326, "HALAVEN": 2.6372436357367146, "HERCEPTIN": 2.8090431608328625, "IBRANCE": 1.0196483898794584, "IMATINIB": 2.6995066922161324, "INLYTA": 12.875761466754383, "IRESSA": 0.7834284816305926, "IRINOTECAN": 1.614836871644317, "KEPPRA": 0.0860049548353213, "KEYTRUDA": 8.739346426999743, "KISQALI": 1.8486866024223572, "LENVATINIB": 21.372306069844967, "LENVIMA": 31.71208721746813, "LONSURF": 2.95466344205187, "MEKINIST": 1.073678467624989, "NEULASTA": 1.4187106408429562, "NEXAVAR": 119.08039126054707, "PANITUMUMAB": 5.486448857272092, "PAZOPANIB": 16.5570235431447, "PEMBROLIZUMAB": 2.638441682756686, "REGORAFENIB": 87.94473375117687, "SORAFENIB": 71.92652538146406, "SPIKEVAX": 0.0056965667234894, "STIVARGA": 108.34766489515604, "SUNITINIB": 21.856100254812542, "SUTENT": 24.47628641913144, "TAGRISSO": 1.7822290237056857, "TAXOTERE": 4.153081478533539, "VAXZEVRIA": 0.0039373813900322, "VECTIBIX": 3.613964997254565, "VOTRIENT": 6.7670847852677065, "XELODA": 21.2059160599237, "ZELBORAF": 5.183406312968176, "null": 0.1353301991551154}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8765.json
index c686c8cdd9b..cc3fa923b7b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8765.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8765.json
@@ -1 +1 @@
-{"BEOVU": 202.60103771510336, "EYLEA": 187.1509105713562, "LANTUS": 4.320915376117243}
\ No newline at end of file
+{"ADALIMUMAB": 1.96606722232214, "APIXABAN": 84.19917760084714, "NEXAVAR": 44.17969983410938, "STIVARGA": 19.616636582000588, "SUTENT": 1.9405706285305, "TAFINLAR": 337.1039155598279, "ZELBORAF": 167.49371806436864, "null": 0.2620250421805962}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8766.json
index a47cfb9bf68..feba9d83140 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8766.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8766.json
@@ -1 +1 @@
-{"AFLIBERCEPT": 26.678009385094903, "AVASTIN": 4.067409674789608, "BEOVU": 461.0423291570274, "BRAFTOVI": 3.8117590166578816, "BROLUCIZUMAB": 392.4118346221145, "BYETTA": 1.0363880976254904, "COVID19": 1.0324999753823665, "EYLEA": 98.6555427228078, "HUMALOG": 1.7119679994605923, "JETREA": 214.3381931016016, "LEVOFLOXACIN": 1.2316415471723978, "LUCENTIS": 50.7839591065242, "MEKINIST": 3.790070874074254, "NEVANAC": 13.201610583454848, "PEGASYS": 1.474362974773943, "PEGINTRON": 1.2240404465923505, "PLAVIX": 1.009075836843943, "TOZINAMERAN": 1.7310257409833198, "VFEND": 2.7677161556824275, "VIAGRA": 4.407535120403818, "VORICONAZOLE": 4.663987563718454, "VOTRIENT": 1.1415714105714072, "XALKORI": 6.663853560790042, "ZOSTAVAX": 3.2667187511970104}
\ No newline at end of file
+{"ADALIMUMAB": 1.3679927218510102, "BUPRENORPHINE": 16.083603235211974, "CIMZIA": 17.15924758291604, "COMIRNATY": 0.4942496836294721, "COSENTYX": 37.96849384521785, "SIMPONI": 43.70860451007567, "STELARA": 9.967090530431143, "null": 0.1759314992598476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8767.json
index 4d7f4100277..11136d49c99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8767.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8767.json
@@ -1 +1 @@
-{"BEOVU": 33.94671956050921, "CELSENTRI": 76.49031122004548, "CLOPIDOGREL": 4.172675890538603, "ELIQUIS": 5.618321305395564, "EYLEA": 104.27708349515328, "HUMALOG": 3.656538496811119, "LANTUS": 11.539845453603514, "PLAVIX": 4.550340032601111, "RIVAROXABAN": 35.231536595786174, "TOPOTECAN": 50.29457033338881, "VIAGRA": 3.433747060083016}
\ No newline at end of file
+{"COMIRNATY": 0.2122736632112877, "VAXZEVRIA": 0.3971979408335531, "null": 1.58196693798179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8768.json
index 0f8b5466f9e..56c439da1a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8768.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8768.json
@@ -1 +1 @@
-{"BEOVU": 576.5055252585477, "BROLUCIZUMAB": 131.73476936043124, "EYLEA": 296.5778188337842, "ZOSTAVAX": 1.6213746373190243, "null": 1.718460442357571}
\ No newline at end of file
+{"ABACAVIR": 0.1157743823782718, "ABASAGLAR": 0.4453654261814557, "ABILIFY": 0.1884392443513237, "ACTOS": 0.5543589893375225, "ADALIMUMAB": 0.136714698695322, "ADCIRCA": 1.976655259086008, "ADEMPAS": 1.4966295459257504, "ADENURIC": 0.6984344576556297, "AERIUS": 1.7048395044883335, "AFINITOR": 0.2773105972034852, "AIMOVIG": 1.2193291911360071, "ALEMTUZUMAB": 0.6826358656049708, "ALIMTA": 0.1247958685108327, "AMBRISENTAN": 1.77936432391901, "AMIKACIN": 0.284733200348044, "AMINOSALICYLIC": 0.2562382053994342, "ANORO": 0.7011557398967361, "ANTIHYPERTENSIVES": 3.6073794538208888, "APIDRA": 0.3881248620626127, "APIXABAN": 0.4207736655677486, "APROVEL": 0.9060212693781532, "ARANESP": 0.1011307567914628, "ARAVA": 0.134028562335513, "ARIPIPRAZOLE": 0.0912723714585288, "ASPARAGINASE": 0.094532194913493, "ATRIPLA": 0.0159618177205215, "AUBAGIO": 0.3771630598404228, "AVAMYS": 0.3118544363589627, "AVANDAMET": 0.4131696836576631, "AVANDIA": 0.5112813014389571, "AVASTIN": 0.1056617540574666, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8769.json
index 28005b5bc67..2077bbbf068 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8769.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8769.json
@@ -1 +1 @@
-{"AFLIBERCEPT": 64.12126205450458, "AVASTIN": 3.25714043731804, "BEOVU": 1901.024326727793, "BROLUCIZUMAB": 1358.4940564151543, "EYLEA": 341.3858393719946}
\ No newline at end of file
+{"DESLORATADINE": 4182.342890189411}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/877.json
index 2ccbbe54644..0905cbd1b64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/877.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/877.json
@@ -1 +1 @@
-{"HEPSERA": 289.51718883776385}
\ No newline at end of file
+{"ALEMTUZUMAB": 23.246263666370005, "ARANESP": 3.435765640501381, "ARAVA": 0.1408535938055052, "ASPARAGINASE": 10.132184254094309, "BUSULFAN": 25.35717138716428, "CELLCEPT": 2.9187250586108844, "CICLOSPORIN": 8.507140257180648, "CLOPIDOGREL": 0.9180002552100158, "COMBIVIR": 8.483671029155875, "COMIRNATY": 0.1072769256314734, "CYTARABINE": 2.7634868926917022, "DARATUMUMAB": 23.13578027934807, "DOXORUBICIN": 4.956175486850026, "ELIQUIS": 0.3110604066308916, "EXJADE": 8.908519567182362, "GARDASIL": 0.4544632452358031, "INCIVO": 4.699734438463656, "IPILIMUMAB": 2.486168795344502, "KEPPRA": 3.762600739027637, "KEYTRUDA": 0.973398743742469, "NPLATE": 8.982684556704914, "PEGASYS": 4.636340723237672, "PEGINTERFERON": 7.197434266897775, "PEGINTRON": 1.198652180276116, "PLAVIX": 4.21298627601648, "REVOLADE": 156.66864436367123, "SOLIRIS": 25.878435733093163, "SPIKEVAX": 0.1202947297265653, "TAGRISSO": 2.4584023089024867, "TASIGNA": 2.0940825800500904, "TEMODAL": 15.6668334258515, "TEMOZOLOMIDE": 42.15746161684291, "THIOTEPA": 16.247896771933043, "TOZINAMERAN": 0.1065318409595694, "VAXZEVRIA": 0.0700852769893915, "VFEND": 1.3661590118230038, "ZYPREXA": 0.6220822474269272, "null": 1.5211931896138975}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8770.json
index 2410bb49669..68ca32eee18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8770.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8770.json
@@ -1 +1 @@
-{"null": 1.2687455096402631}
\ No newline at end of file
+{"BEDAQUILINE": 661.4397568393958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8771.json
index 8bd3176dd25..01bd26704a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8771.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8771.json
@@ -1 +1 @@
-{"null": 1.6208328504738556}
\ No newline at end of file
+{"null": 0.5739255987430947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8772.json
index 51e468297d0..fe9fb53e246 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8772.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8772.json
@@ -1 +1 @@
-{"BUDESONIDE": 289.63836759828695, "NUCALA": 10.766900999354563}
\ No newline at end of file
+{"LANTUS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8773.json
index 84f296ad8d7..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8773.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8773.json
@@ -1 +1 @@
-{"null": 1.57396851788585}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8774.json
index 6e5b754a614..6225d8d5a15 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8774.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8774.json
@@ -1 +1 @@
-{"KEYTRUDA": 2.095050262815306, "null": 1.8163567863314884}
\ No newline at end of file
+{"BYETTA": 134.9346561572111, "JANUMET": 103.4005512457913, "JANUVIA": 99.443323290227, "LANTUS": 4.743813495588173, "null": 0.2361946611479491}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8775.json
index 5483aa95bc1..31746e0aa92 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8775.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8775.json
@@ -1 +1 @@
-{"null": 1.736640177686496}
\ No newline at end of file
+{"HUMALOG": 17.14555952848887, "null": 0.6202658482019537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8776.json
index f5039f45fcb..3cf5c6c131a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8776.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8776.json
@@ -1 +1 @@
-{"null": 1.3950246367703545}
\ No newline at end of file
+{"null": 0.5338888889812123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8777.json
index 5094efaf7b3..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8777.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8777.json
@@ -1 +1 @@
-{"IPILIMUMAB": 30.65577505972935, "KEYTRUDA": 9.601844134459114, "MEKINIST": 29.88034123290466, "OPDIVO": 39.36864820526257, "PEGASYS": 10.081442698463515, "PEGINTERFERON": 38.49693201227187, "PEGINTRON": 25.70195007680612, "TOZINAMERAN": 1.6990362065401012}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8778.json
index ff7c64fe970..6f4275cb195 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8778.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8778.json
@@ -1 +1 @@
-{"null": 1.368720717778667}
\ No newline at end of file
+{"ABASAGLAR": 2.1075353199285973, "ABRAXANE": 3.9089567940666585, "ACTOS": 3.0423712227496096, "AFINITOR": 0.32762868638858, "AMINOSALICYLIC": 1.1319035020460684, "APIDRA": 0.9427956660092704, "ARAVA": 0.0350928866779309, "AUBAGIO": 0.285932266479969, "AVANDIA": 0.5539217833251336, "BYDUREON": 10.424350759772633, "BYETTA": 145.43536473368553, "CELLCEPT": 0.2922047852405003, "CIMZIA": 0.3049222299905854, "COAPROVEL": 4.139022703628517, "COMIRNATY": 0.0252935292167018, "COSENTYX": 0.2798841169831971, "CYMBALTA": 0.0958735930752864, "ELIQUIS": 1.0721129870674038, "EUCREAS": 25.51502488151719, "EXFORGE": 1.095663100537594, "FASLODEX": 0.5019674163856109, "FORSTEO": 0.5658354769092822, "FORXIGA": 1.1668811905499972, "GALVUS": 4.491101435650726, "HARVONI": 0.7471432020171555, "HUMALOG": 1.6833412190103545, "INSULIN": 1.4077289384371527, "IRINOTECAN": 2.118938546386959, "JAKAVI": 1.1879417960947252, "JANUMET": 51.43551714075334, "JANUVIA": 65.45542945970087, "JARDIANCE": 2.0855472431953337, "LANTUS": 2.206690370942671, "LEVEMIR": 2.6325635629428947, "MEKINIST": 0.5295212446778009, "METFORMIN": 4.979488155907248, "METHOTREXATE": 0.3368622877959926, "ONGLYZA": 10.470210013694052, "OPSUMIT": 0.3965329595823741, "PEGASYS": 0.2151475582704879, "PLAVIX": 0.1992027677142032, "RINVOQ": 1.022126216796177, "ROACTEMRA": 0.5568379182838193, "RYBELSUS": 3.8924952381226112, "SAXENDA": 2.896273958730941, "SIMPONI": 1.0480346961394265, "SOLIRIS": 0.38062588726516, "SPIKEVAX": 0.0218314812608175, "STELARA": 0.7074968546832645, "SUTENT": 0.4020317046004834, "TOZINAMERAN": 0.026541818043723, "TRACLEER": 0.6387979006092683, "TRESIBA": 3.7372466413431993, "TRULICITY": 8.24885553272093, "VAXZEVRIA": 0.0075791740275174, "VELMETIA": 8.513084692751528, "VICTOZA": 40.6917403216226, "XELJANZ": 0.4051869142606309, "XOLAIR": 0.6849657172091586, "XTANDI": 0.3065899440911602, "ZYPREXA": 0.3161401511030198, "null": 1.261468558870397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8779.json
index d5b29892491..48d00e6dee9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8779.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8779.json
@@ -1 +1 @@
-{"AIMOVIG": 7.2024479200543645, "CLOPIDOGREL": 3.915238652128057, "ISENTRESS": 119.36599752473684, "KEPPRA": 2.833147889592419, "SIMPONI": 5.013179863358996}
\ No newline at end of file
+{"ABRAXANE": 22.55899605603173, "APIDRA": 2.7809902294941806, "BRILIQUE": 4.062006378083061, "BYDUREON": 18.96954846354812, "BYETTA": 218.8257052472164, "COMIRNATY": 0.0342823248393873, "ELIQUIS": 0.6390849008588779, "ENBREL": 1.090848611048275, "EUCREAS": 13.566853639311631, "HUMALOG": 0.8814320269640507, "IRINOTECAN": 17.025192850067153, "JANUMET": 110.3997427617222, "JANUVIA": 93.2899845189841, "LANTUS": 0.7999401464716761, "SAXENDA": 2.9478176547389245, "SOLIRIS": 1.7631672617056122, "STELARA": 1.5515473097826415, "TRULICITY": 7.679010726588554, "VICTOZA": 55.46777742420722, "null": 0.1322364594534776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/878.json
index fa63b24608c..85bf38f230d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/878.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/878.json
@@ -1 +1 @@
-{"HEPSERA": 323.52143498466376}
\ No newline at end of file
+{"APIDRA": 0.9312527316529678, "APIXABAN": 0.504310195524207, "ARAVA": 0.069007904749447, "BENZODIAZEPINE": 6.828105434603596, "BRIDION": 10.29115473572987, "BRILIQUE": 2.8860320403588813, "BUPIVACAINE": 8.641401786173748, "BUPRENORPHINE": 1.2956525472427785, "CICLOSPORIN": 1.202164752032279, "COMIRNATY": 0.1833609298740817, "CYMBALTA": 0.2907396079122862, "CYTARABINE": 1.0013327365776603, "DEXAMETHASONE": 0.6329167980244566, "DULOXETINE": 5.056103847976727, "FENTANYL": 14.500715243229545, "GARDASIL": 0.974982514975613, "HYDROCORTISONE": 4.196350242297737, "IBUPROFEN": 3.631296901804918, "INFANRIX": 42.26384642761485, "JARDIANCE": 0.4320706285407976, "KEPPRA": 1.485423655784218, "LANTUS": 0.2199521887420398, "LEVETIRACETAM": 3.6717342005658433, "LEVOFLOXACIN": 0.591714454337787, "LYRICA": 0.7772749630452788, "MIDAZOLAM": 16.42819068423923, "MMRVAXPRO": 4.161526218099412, "NAGLAZYME": 8.688030289211124, "NALOXONE": 69.22507979239305, "NOT": 2.2698479644444087, "NUCALA": 0.8430445216442133, "OLANZAPINE": 1.1971623924143566, "PEGINTRON": 0.5432362427747177, "PLAVIX": 0.3092144510013846, "PREVENAR": 19.557334292200004, "ROTATEQ": 14.852593495546712, "SOMATROPIN": 12.316305373243914, "SPIKEVAX": 0.0983848467480472, "SPINRAZA": 8.790394260314505, "SUBOXONE": 0.5950290584442834, "SUFENTANIL": 3.863862385315131, "SYNAGIS": 57.086794905206126, "TOZINAMERAN": 0.1722347197722108, "TRACLEER": 0.8459552156816917, "VAXZEVRIA": 0.1041993830065247, "XOLAIR": 0.4087565778007051, "XYREM": 3.7164870615315473, "ZYPREXA": 1.229596942733189, "null": 2.9961624685381074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8780.json
index 1fd6956179d..73ba0e607c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8780.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8780.json
@@ -1 +1 @@
-{"ACETYLSALICYLIC": 1.1450011114268448, "ACLIDINIUM": 1.0378641016850796, "ADEMPAS": 1.2022057457323152, "AERIUS": 1.2020220386026277, "AIMOVIG": 1.1156060668051069, "AKYNZEO": 1.922516183722401, "ALIMTA": 1.290872718823105, "ALOXI": 1.1617001869690566, "AMINOSALICYLIC": 1.280334086872677, "APTIVUS": 2.333558757706116, "AVASTIN": 1.4496848740572703, "AXURA": 1.1487942445210362, "BAQSIMI": 1.5613231875743518, "BEDAQUILINE": 2.6780495181921333, "BEVACIZUMAB": 1.417556729107509, "BEXSERO": 2.693540825851686, "BEXTRA": 1.4131628670651288, "BIKTARVY": 1.0143901713411818, "BINIMETINIB": 1.37768037786918, "BOCEPREVIR": 1.1609571932704748, "BOSULIF": 1.651400613123582, "BRAFTOVI": 1.734879641178891, "BRINTELLIX": 2.7074595658670733, "BUCCOLAM": 1.7381872230806763, "BUPRENORPHINE": 1.4046747442481209, "BYDUREON": 1.7170908998572492, "BYETTA": 1.6496509316011216, "CAPECITABINE": 1.8566405253033396, "CERVARIX": 1.505251216312644, "CHAMPIX": 1.4454335936941116, "CHORIOGONADOTROPIN": 2.3453199374292777, "CINACALCET": 2.500601527984508, "COAPROVEL": 1.33637483800175, "COBIMETINIB": 1.4379184799781533, "COMBIVIR": 1.1587883540226414, "COMPRESSION": 3.670870204583478, "CONSTELLA": 8.733344386982521, "COTELLIC": 1.4721826857028908, "COVID19": 1.3396363548146504, "CRIXIVAN": 1.5676186806517165, "CRIZOTINIB": 1.516806097828248, "CYMBALTA": 1.4359339584973172, "DABRAFENIB": 1.0045919863691728, "DARBEPOETIN": 1.2090187333096378, "DELAMANID": 3.105659917760229, "DEXRAZOXANE": 1.860836555997059, "DINUTUXIMAB": 1.4659093614440382, "DOCETAXEL": 1.5067813957885772, "DOXORUBICIN": 1.0215462396648334, "DUKORAL": 1.332770610334035, "DULAGLUTIDE": 1.5460090841516672, "EBILFUMIN": 9.534573366778202, "EBIXA": 1.0030839046722917, "EFFICIB": 2.60873415525624, "ELASOMERAN": 1.0471359248547796, "ELLAONE": 1.2846528055467583, "EMEND": 1.5694579187578397, "EMPAGLIFLOZIN": 1.5357586790221085, "EPIDYOLEX": 1.8785126990937149, "EPIRUBICIN": 3.3432163675487208, "ERBITUX": 1.7228792733744394, 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2.44229058626994, "NINLARO": 1.3552588111093549, "NINTEDANIB": 2.989973493555093, "NIVOLUMAB": 1.2661841799545146, "NORVIR": 1.1132388394111072, "NSAID'S": 2.7733782287109467, "NUSINERSEN": 2.348133439257855, "NUTROPIN": 1.076750212315001, "OFEV": 2.462672681721218, "OLAPARIB": 1.8442617455772432, "OMALIZUMAB": 1.2378273970795357, "OMNITROPE": 1.211673741237495, "ONCASPAR": 3.249583682998379, "ONTRUZANT": 1.492400734986446, "OSELTAMIVIR": 1.905975590228645, "OZEMPIC": 2.4038991708639057, "PACLITAXEL": 1.163126083641404, "PALBOCICLIB": 1.5806263625791015, "PAXLOVID": 1.0423893144006098, "PEGASPARGASE": 1.3412845456882254, "PEGASYS": 1.1203450852847223, "PEGINTERFERON": 1.028452392643142, "PEGINTRON": 1.2262936827883295, "PEMETREXED": 1.890242738647437, "PERTUZUMAB": 1.0946685121071034, "PIQRAY": 1.4131130580988736, "PREOTACT": 1.7740802141714127, "PREVENAR": 1.9887466223321857, "PRIVIGEN": 2.203392437805078, "PROQUAD": 1.1582574820548794, "PROVENGE": 1.411863532947166, "PUREGON": 1.3897000384763536, "RADIATION": 1.8138402340807789, "RAPISCAN": 2.4269932621366284, "REPAGLINIDE": 1.625372357159445, "RILUTEK": 1.2315513666604283, "ROTARIX": 3.4204404361414475, "ROTASHIELD": 2.4963923697950223, "ROTATEQ": 5.79298788801477, "RUBRACA": 2.1140566544432366, "RYBELSUS": 5.612713599001174, "RYDAPT": 1.8334243541006925, "SAXENDA": 4.034125696313054, "SELINCRO": 2.338238382155612, "SIGNIFOR": 1.6653401212109848, "SILGARD": 1.1968563534369152, "SIRTURO": 1.4065080116455226, "SITAGLIPTIN": 1.7125152103939232, "SOTORASIB": 1.097899877849237, "SPINRAZA": 1.7088213621029986, "STAVUDINE": 1.2346894233129933, "SUBOXONE": 1.2931456667296497, "SUBSTANCE": 2.046888396228674, "SUTENT": 1.4576550902012009, "SYMTUZA": 1.4274813392769647, "SYNAGIS": 1.5864880218430284, "SYNFLORIX": 1.714667124431322, "TAFINLAR": 1.516492879102256, "TAMIFLU": 3.5577108456382702, "TARCEVA": 1.8548174844784175, "TAXOTERE": 1.261986991080676, "TEGADERM": 1.2872558600083472, "TEGAFUR": 1.8804521466480344, 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\ No newline at end of file
+{"BYETTA": 108.53505549207446, "IRINOTECAN": 178.41092115362937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8781.json
index a033f78a4a7..47292e84840 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8781.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8781.json
@@ -1 +1 @@
-{"COVID19": 2.492063343113202, "INFANRIX": 15.627793947683672, "MMRVAXPRO": 3.1169022698731026, "ROTATEQ": 40.69756006526693, "SUBOXONE": 5.692490690362532, "TOZINAMERAN": 2.3734938015381157, "TRULICITY": 11.763332078493436, "null": 1.0446950431435098}
\ No newline at end of file
+{"MICARDIS": 212.41774211152327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8782.json
index 29148477631..7e86e20222c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8782.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8782.json
@@ -1 +1 @@
-{"null": 1.4049867443840058}
\ No newline at end of file
+{"BYETTA": 87.85846710344173, "JANUMET": 48.44190130591417, "JANUVIA": 26.179956446116638, "VICTOZA": 91.22408240378684, "null": 0.6710433165343622}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8783.json
index 9cbad01d2ad..49331912cd4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8783.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8783.json
@@ -1 +1 @@
-{"null": 1.0575416466027538}
\ No newline at end of file
+{"OFEV": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8784.json
index 701a143eb41..38105fe53a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8784.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8784.json
@@ -1 +1 @@
-{"null": 7.0424728888252455}
\ No newline at end of file
+{"BYDUREON": 6.87613742272661, "BYETTA": 37.945158051264414, "COMIRNATY": 0.0639597641331782, "JANUMET": 25.092972280027844, "JANUVIA": 25.0127214099448, "SAXENDA": 13.737458709428653, "TRULICITY": 8.842036352729702, "VICTOZA": 13.266343079431127, "null": 0.8298573254994173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8785.json
index 82b914b2d34..67cd53a2514 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8785.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8785.json
@@ -1 +1 @@
-{"null": 14.07430130606686}
\ No newline at end of file
+{"APIDRA": 7.439313305864131, "BYDUREON": 4.500252762428124, "BYETTA": 6.109646030140581, "CICLOSPORIN": 1.0429523105083394, "COMIRNATY": 0.1179114469895432, "ELIQUIS": 0.929864179822831, "HUMALOG": 11.37176756735334, "INSULIN": 2.603516878505885, "JANUMET": 5.6894870901822685, "JANUVIA": 7.704838901039387, "KEYTRUDA": 1.6483928181543634, "LANTUS": 8.72538235220352, "PEGASYS": 1.0719464148645936, "PEGINTRON": 2.273628560753431, "SAXENDA": 7.133313633904936, "SUTENT": 1.0808865106667351, "TOZINAMERAN": 0.2086819169916851, "TRULICITY": 13.075804190613146, "VICTOZA": 14.42145555647259, "XELJANZ": 2.158852590551485, "ZYPREXA": 2.9054042186608093, "null": 0.9526319973153702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8786.json
index 03b778baaf1..ef558805e3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8786.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8786.json
@@ -1 +1 @@
-{"null": 1.0020279253073698}
\ No newline at end of file
+{"BYETTA": 81.44228212874353, "JANUMET": 71.33489388512686, "JANUVIA": 21.877513668252533, "null": 0.3858219597912754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8787.json
index 67e1a7fde90..21ac89825dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8787.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8787.json
@@ -1 +1 @@
-{"JARDIANCE": 56.10683930616301}
\ No newline at end of file
+{"BYETTA": 67.92853781353745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8788.json
index 2d670e7cb21..466bc557967 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8788.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8788.json
@@ -1 +1 @@
-{"null": 1.1558284474965004}
\ No newline at end of file
+{"null": 1.195676110525418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8789.json
index 4aa6bad3889..6c8cb485a2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8789.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8789.json
@@ -1 +1 @@
-{"ADALIMUMAB": 2.6975547463442684, "CELLCEPT": 16.504554685153046}
\ No newline at end of file
+{"null": 0.7126294333448642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/879.json
index 0d6df8bb608..04c99124262 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/879.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/879.json
@@ -1 +1 @@
-{"GARDASIL": 6.578791146617865, "null": 1.2420881786854028}
\ No newline at end of file
+{"INSULIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8790.json
index 5467bc91494..c8efbab1284 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8790.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8790.json
@@ -1 +1 @@
-{"COVID19": 5.1074949117251975, "TOZINAMERAN": 10.100763130343555}
\ No newline at end of file
+{"STIVARGA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8791.json
index ea394941733..61219823aa0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8791.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8791.json
@@ -1 +1 @@
-{"null": 2.527309505797336}
\ No newline at end of file
+{"ASPARAGINASE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8792.json
index 5a1dc4f9c84..334d739276e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8792.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8792.json
@@ -1 +1 @@
-{"TOZINAMERAN": 3.714884121069701}
\ No newline at end of file
+{"null": 1.0482035107283596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8793.json
index cc5d8ad0a04..0a7d84a5f73 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8793.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8793.json
@@ -1 +1 @@
-{"null": 1.824127779729384}
\ No newline at end of file
+{"BENLYSTA": 6.597701511130713, "BYETTA": 5.567986881249192, "COMIRNATY": 0.0678430143344624, "ICLUSIG": 13.177115422234298, "IPILIMUMAB": 10.572297065075528, "JANUMET": 9.063828452566163, "JANUVIA": 8.147849380561984, "KEYTRUDA": 2.741945148844525, "NEXAVAR": 16.551433861855426, "OPDIVO": 7.751427497641741, "PEGASYS": 1.9237127841152817, "SUTENT": 1.2570643560533297, "TASIGNA": 8.12767872220955, "TRULICITY": 5.944964742295338, "VICTOZA": 11.32310069560502, "null": 1.112487947919606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8794.json
index c56f512ed09..96d819a8a0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8794.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8794.json
@@ -1 +1 @@
-{"FORXIGA": 65.95026107523228, "JARDIANCE": 40.03715347361926}
\ No newline at end of file
+{"BYETTA": 18.18703435115625, "COMBIVIR": 56.3254648398669, "COMIRNATY": 0.1437042182075472, "HUMALOG": 7.267463030229279, "JANUMET": 6.70072785338633, "KEYTRUDA": 3.436141387702192, "LANTUS": 2.819457184178765, "TRULICITY": 13.605000342563953, "null": 0.951108502944724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8795.json
index 5c7274fdbf6..0f6aa689f16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8795.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8795.json
@@ -1 +1 @@
-{"ALDARA": 33.75958637737784, "FORXIGA": 11.274349233144648, "ISENTRESS": 16.996612894485715, "JARDIANCE": 15.014319815932826, "PEGASYS": 1.1767809262167948, "null": 4.543923025530843}
\ No newline at end of file
+{"null": 0.7883024379779383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8796.json
index 084611baac6..2e23db0c912 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8796.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8796.json
@@ -1 +1 @@
-{"COSENTYX": 9.740006650404643, "EMPAGLIFLOZIN": 81.26775543369882, "FORXIGA": 41.21270498778955, "JARDIANCE": 32.133074110426506, "KARVEA": 155.6799966179927, "NUCALA": 2.5850782775963808, "SIMPONI": 1.891557884647556, "STELARA": 1.843304093240404, "SUBOXONE": 2.483180403894271, "null": 1.068207391121226}
\ No newline at end of file
+{"null": 1.1954473468260058}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8797.json
index e07adea90d2..7d2ec926818 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8797.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8797.json
@@ -1 +1 @@
-{"EMPAGLIFLOZIN": 29.0323505464779, "FORXIGA": 9.72382697305281, "JARDIANCE": 9.264102495907665, "null": 3.707920699882663}
\ No newline at end of file
+{"null": 0.4742600636610668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8798.json
index 6dd110b3ac8..bbd3c1f9bfc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8798.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8798.json
@@ -1 +1 @@
-{"FASLODEX": 11.457254571015572, "FORXIGA": 6.768052558502779, "IBRANCE": 2.727969265397052, "JARDIANCE": 5.678772535928389, "null": 2.716524636869612}
\ No newline at end of file
+{"BYETTA": 67.00228546997259, "ISENTRESS": 76.23166144588866, "JANUMET": 23.843657714514, "JANUVIA": 31.445443621359328, "TRULICITY": 13.502031179557513, "VICTOZA": 35.71259746322911, "null": 0.4719365501491707}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8799.json
index 7d76c7a9a5d..441377abf14 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8799.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8799.json
@@ -1 +1 @@
-{"JARDIANCE": 15.98956729932267, "null": 3.952273887291944}
\ No newline at end of file
+{"BYETTA": 32.80685181748222, "JANUMET": 21.919828069078477, "JANUVIA": 11.325499520086856, "LANTUS": 2.942659601520447, "VICTOZA": 51.11455077783836, "null": 0.5412857299214837}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/88.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/88.json
index 19c062499ae..db92efe5b20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/88.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/88.json
@@ -1 +1 @@
-{"null": 2.387804269380746}
\ No newline at end of file
+{"SIMPONI": 8.93857092349803, "null": 0.7530383509764574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/880.json
index 011503b6a2c..c1a8687c9dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/880.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/880.json
@@ -1 +1 @@
-{"null": 1.9063802394215228}
\ No newline at end of file
+{"FENTANYL": 16.405934064100283, "LEVETIRACETAM": 14.029602172204472, "MIDAZOLAM": 29.36131940314148, "SYNAGIS": 53.88703751774717, "null": 1.6997074111950088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8800.json
index 8de94f10fb5..1a9b85c4513 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8800.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8800.json
@@ -1 +1 @@
-{"null": 10.08921392241555}
\ No newline at end of file
+{"AFINITOR": 175.04485266481146, "BYETTA": 44.55632003066437, "CAPECITABINE": 29.45549400242277, "EVEROLIMUS": 144.42396150719617, "JANUMET": 8.785508068521194, "JANUVIA": 7.117943810599132, "LUTATHERA": 167.3917756535081, "SUTENT": 20.864515423654787, "null": 0.1827710342570365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8801.json
index 0f6bff2b397..a2c462edd9e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8801.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8801.json
@@ -1 +1 @@
-{"FORXIGA": 19.13337162544912, "JARDIANCE": 7.057045069208138, "null": 1.7208182350346195}
\ No newline at end of file
+{"AFINITOR": 97.6442848512827, "BYETTA": 96.14014129169658, "CAPECITABINE": 45.93676545170948, "OLANZAPINE": 11.679722798184752, "SUTENT": 12.17630317638663, "null": 0.0936829849936712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8802.json
index 7fc22308818..ffe225a809d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8802.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8802.json
@@ -1 +1 @@
-{"null": 4.905367865470461}
\ No newline at end of file
+{"LUTATHERA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8803.json
index 1edc14cc00e..3f95b6b6df7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8803.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8803.json
@@ -1 +1 @@
-{"CIMZIA": 1.3192544880499466, "COSENTYX": 4.146334966831085, "DEXAMETHASONE": 1.7374040451348831, "FENTANYL": 1.744173669047423, "FORXIGA": 50.62573441711976, "INVOKANA": 25.288627745971905, "JARDIANCE": 74.68813130779185, "RINVOQ": 3.221663923383557, "STELARA": 2.532104647644841, "null": 1.1309574948814851}
\ No newline at end of file
+{"ASPARAGINASE": 119.01717524869828, "BYETTA": 26.2798904508502, "JANUMET": 18.22553823376625, "JANUVIA": 11.084099614188649, "ONCASPAR": 91.4197460099163, "VICTOZA": 25.739112851880428, "ZYPREXA": 4.596008826205094, "null": 0.7777131476192178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8804.json
index 24f281bdec8..f27896364c3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8804.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8804.json
@@ -1 +1 @@
-{"CAPECITABINE": 7.722920801418919, "COMIRNATY": 1.065042450547022, "FORXIGA": 4.541726296017542, "JARDIANCE": 6.12018106651269, "TOZINAMERAN": 1.398463380763204, "null": 2.0586039416863424}
\ No newline at end of file
+{"null": 0.4649560727276131}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8805.json
index 3e810fd0cd9..5b5b360d5b5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8805.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8805.json
@@ -1 +1 @@
-{"BETMIGA": 22.8773739055385, "ELLAONE": 22.795403911648453, "EMPAGLIFLOZIN": 38.23713240228954, "FORXIGA": 47.7090247619072, "IBRANCE": 1.2388484012974776, "JARDIANCE": 51.78722738505421, "null": 2.211223070873932}
\ No newline at end of file
+{"BYETTA": 93.48750618786488, "JANUMET": 191.12365993342445, "JANUVIA": 101.2944267596451}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8806.json
index f2e8d4d4df5..c0a5e9f5891 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8806.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8806.json
@@ -1 +1 @@
-{"null": 2.8927176922238345}
\ No newline at end of file
+{"JANUMET": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8807.json
index f7a6cc30024..fbf0112fbd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8807.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8807.json
@@ -1 +1 @@
-{"JARDIANCE": 21.93893996300957, "null": 2.538092675704668}
\ No newline at end of file
+{"BYETTA": 107.68938426721324, "JANUMET": 170.09209210976098, "JANUVIA": 242.48014885587503}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8808.json
index 5f23dde3c63..1933c4a1896 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8808.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8808.json
@@ -1 +1 @@
-{"EMPAGLIFLOZIN": 60.44133240945552, "FORXIGA": 203.05300413208548, "JARDIANCE": 130.673196223988}
\ No newline at end of file
+{"BYETTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8809.json
index 7df6881f6a7..d11d99d8d82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8809.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8809.json
@@ -1 +1 @@
-{"LUVERIS": 1068.125355537261, "null": 1.3680251339460054}
\ No newline at end of file
+{"ABACAVIR": 0.4028660712440021, "ABILIFY": 0.4068347519121827, "ACTOS": 2.0136805132463795, "ADALIMUMAB": 0.1612893075347333, "ADENURIC": 2.141513994037576, "AFINITOR": 0.4648237071189627, "AIMOVIG": 0.3052981134023517, "ALIMTA": 0.5611286379638144, "AMINOSALICYLIC": 0.8197276044475384, "APIDRA": 0.6388470943200268, "ARANESP": 0.1579549964389309, "ARAVA": 0.2519602767633588, "ASPARAGINASE": 5.427743888188936, "ATAZANAVIR": 0.9651631751076036, "ATRIPLA": 0.1488815568237563, "AUBAGIO": 1.3846446251205564, "AVANDIA": 0.524033924617545, "AVASTIN": 0.3942597091781622, "AVONEX": 2.5350633914946816, "AXITINIB": 0.7625190915421018, "AZATHIOPRINE": 3.7274515180109935, "BARACLUDE": 1.8060005453800676, "BENLYSTA": 0.529298279563024, "BETAFERON": 0.4859845596735921, "BIKTARVY": 1.6973502712080624, "BLINATUMOMAB": 3.1819150861582477, "BOSULIF": 1.5094296328519126, "BOSUTINIB": 10.368311083845008, "BRAFTOVI": 1.2400205121392276, "BRINTELLIX": 0.4612435527502405, "BUDESONIDE": 0.8856878146489969, 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11.936607486507832, "STELARA": 0.7039796933526977, "STIVARGA": 0.4323424902556909, "STRIBILD": 0.2103177399269666, "SUBOXONE": 0.8718468621805399, "SUFENTANIL": 0.7270324168946111, "SUSTIVA": 3.2123651582107637, "SUTENT": 1.0451949096132558, "TAGRISSO": 0.5348209780832702, "TAMIFLU": 1.0666820321355162, "TASIGNA": 8.25169786910044, "TIVICAY": 2.5533012752926343, "TOCILIZUMAB": 1.145127250347365, "TOUJEO": 1.2421264363534903, "TOZINAMERAN": 0.0823154627375539, "TRACLEER": 0.6581247423780414, "TREMFYA": 0.5279846243346743, "TRIUMEQ": 3.15892929738473, "TRULICITY": 29.629314673776637, "TRUVADA": 0.1483998085204939, "VAXZEVRIA": 0.0349950237125379, "VEDOLIZUMAB": 3.0795259033172697, "VEKLURY": 1.2934172869447833, "VELMETIA": 23.734504115941363, "VELTASSA": 0.8570747451618815, "VFEND": 0.7917691327087333, "VICTOZA": 72.58735547911554, "VIMPAT": 0.3133364761212662, "VIRAMUNE": 3.915676478387241, "VIREAD": 1.8496287127634707, "VOTRIENT": 2.1518282849842776, "XARELTO": 0.3314088025144648, "XELJANZ": 0.5462690905893569, "XOLAIR": 0.2649897360189163, "YERVOY": 1.0160284835181352, "ZELBORAF": 1.1874904835313504, "ZEPATIER": 1.5535744427246012, "ZERIT": 22.351247477085668, "ZIAGEN": 2.743751463134501, "ZOSTAVAX": 0.1342274012759073, "ZYPREXA": 5.188768890673827, "null": 0.8343476467938163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/881.json
index ae7ac9cbe52..ddf3667cf09 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/881.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/881.json
@@ -1 +1 @@
-{"OLANZAPINE": 12.69115397249462, "null": 5.630591657227035}
\ No newline at end of file
+{"TESTOSTERONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8810.json
index cf51f106b60..e0e498227a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8810.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8810.json
@@ -1 +1 @@
-{"ABATACEPT": 6.152885800556383, "ATRIPLA": 1.1596175135741529, "AUBAGIO": 28.62201317376707, "BELIMUMAB": 127.29738705648506, "BENLYSTA": 5.213523591683449, "CIMZIA": 1.3138436562782132, "ENBREL": 6.17933633199521, "ESBRIET": 7.902613951037277, "FIRDAPSE": 10.844775682483965, "GARDASIL": 1.2545123277421324, "HUMALOG": 1.1723171628316875, "KEPPRA": 1.293266706310262, "LANTUS": 7.077519893082665, "SHINGRIX": 2.5429212659521205, "STRIBILD": 4.229195771901956, "TRUVADA": 1.091558910257506, "XELJANZ": 2.885538718455632, "XTANDI": 2.140420282989459}
\ No newline at end of file
+{"ABACAVIR": 0.2410503521269301, "ABILIFY": 0.5619126112988581, "ADENURIC": 6.239271696451349, "ADVAGRAF": 8.629185471714257, "AERIUS": 2.3323422196112187, "AIMOVIG": 0.1520396710069096, "ALIMTA": 0.9909196496308044, "AMINOSALICYLIC": 0.7184064259945558, "APROVEL": 3.834222051394935, "ARAVA": 0.0666652657858118, "ASPARAGINASE": 13.164815233504898, "ATAZANAVIR": 0.721476626084694, "ATRIPLA": 0.0238321874059889, "AUBAGIO": 0.5978470661278812, "AVANDIA": 0.1937041245437264, "AVASTIN": 0.4637636877930577, "AXITINIB": 2.1997530111795074, "AZATHIOPRINE": 1.7883132535599862, "BENLYSTA": 0.3475394400027032, "BEVACIZUMAB": 0.927552872336993, "BIKTARVY": 1.8545398133425373, "BRAFTOVI": 2.0701855016824218, "BRILIQUE": 0.4912441564614337, "BRINTELLIX": 0.6797032627720695, "BUDESONIDE": 0.7331461414318377, "BUSULFAN": 1.0897074080069946, "BYDUREON": 4.754094815536652, "BYETTA": 24.718934351883235, "CABOMETYX": 0.6040337548150205, "CAELYX": 0.7602824710859031, "CANCIDAS": 2.73345514031356, 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"LENVIMA": 1.7183309426239444, "LEVEMIR": 1.1018115999122362, "LEVETIRACETAM": 0.9497097739914098, "LEVOFLOXACIN": 0.4511597791695308, "LIRAGLUTIDE": 13.392195914457334, "LYRICA": 0.7971486390390337, "MEKINIST": 0.8884327325250103, "MERCAPTOPURINE": 6.945241939698022, "METFORMIN": 4.618796183190683, "METHOTREXATE": 0.7109948464425314, "MIDAZOLAM": 1.3289413062899118, "NEXAVAR": 3.215301896133324, "NILOTINIB": 4.265214066736592, "NORVIR": 2.147938191645139, "NOXAFIL": 1.325953272012913, "OFEV": 0.441921860190449, "OLANZAPINE": 1.2470029639002178, "ONCASPAR": 24.737938345639527, "ONGLYZA": 18.78576684086436, "OPDIVO": 0.5847872503564648, "OZEMPIC": 5.378289760485154, "PANTOPRAZOLE": 0.5717092443887729, "PEGASYS": 1.117846462852624, "PEGINTERFERON": 2.693064518090718, "PEGINTRON": 2.2729548882269266, "PEMBROLIZUMAB": 0.5228301437153839, "PLAVIX": 0.8507693903474043, "PRADAXA": 2.6475803914390323, "PREGABALIN": 0.656515448855654, "REMICADE": 1.7286701553785535, "REPAGLINIDE": 5.093129475791856, "REYATAZ": 3.938583819082288, "RIBAVIRIN": 0.8156595022852579, "RILUTEK": 12.25409631709886, "RILUZOLE": 15.922121402782386, "RINVOQ": 0.4182145356935438, "RISPERIDONE": 1.2181159625535525, "ROACTEMRA": 2.469714726131123, "RYBELSUS": 14.240260598248671, "SAXENDA": 11.630526219325995, "SIMEPREVIR": 7.570739143679191, "SIMPONI": 0.3863680016240082, "SOLIRIS": 0.4193554503258615, "SOMATROPIN": 6.354695258301056, "SOVALDI": 2.857094945402418, "SPECTRILA": 73.61796610087383, "SPIKEVAX": 0.0758060811732171, "SPRYCEL": 0.6898035595549034, "STELARA": 0.6761475633174037, "STIVARGA": 0.6122494215339147, "STRIBILD": 0.1921674434961933, "SUBOXONE": 0.3823220166282581, "SUSTIVA": 12.270590573638067, "SUTENT": 0.4976414358302126, "TAMIFLU": 1.358338495176456, "TASIGNA": 4.088881982234512, "TIGECYCLINE": 7.436616929245351, "TOCILIZUMAB": 2.2247782265943603, "TOZINAMERAN": 0.1326128950007254, "TRIUMEQ": 2.332336366873145, "TRULICITY": 12.953750442096418, "TRUVADA": 0.2886081340427511, "VAXZEVRIA": 0.0327537365496714, "VEKLURY": 3.7315142581223, "VELMETIA": 39.9984755530353, "VFEND": 0.4221199755084455, "VICTOZA": 48.31485992133669, "VILDAGLIPTIN": 15.667470033671016, "VIREAD": 1.074725873968572, "VOTRIENT": 1.5512993847943533, "XELEVIA": 63.37477913824392, "XELJANZ": 0.1036389354036227, "XOLAIR": 0.2034127777808465, "ZELBORAF": 1.436637375302675, "ZERIT": 21.72216881088159, "ZYPREXA": 2.774000244627797, "null": 1.2923284319168178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8811.json
index 6824d182cc4..685a2d5bef8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8811.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8811.json
@@ -1 +1 @@
-{"GARDASIL": 2.061062885187697, "KALETRA": 6.187372991036302, "KEPPRA": 2.008718277515829, "LANTUS": 1.9916956721298111, "SUTENT": 2.1783393726089675, "TOZINAMERAN": 1.7243629683619806, "XELJANZ": 1.7704986857774767, "XTANDI": 2.150272596352453, "null": 1.3825567520613065}
\ No newline at end of file
+{"AMINOSALICYLIC": 8.890763123775479, "BOSULIF": 10.71252557069622, "BUPRENORPHINE": 4.597750402030978, "BYETTA": 92.87566972861912, "COMIRNATY": 0.050049668011214, "JANUMET": 34.55483972598498, "JANUVIA": 33.63753706259275, "LANTUS": 1.8967043571383588, "PEGASYS": 0.9695768003668808, "SUBOXONE": 2.4179600483307486, "TRULICITY": 5.617763541971441, "VICTOZA": 21.432513941725308, "ZYPREXA": 4.508069701474809, "null": 0.7860921969888608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8812.json
index 0ccb492a36f..d3d62e38025 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8812.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8812.json
@@ -1 +1 @@
-{"ESBRIET": 52.48563694473251, "OPSUMIT": 85.663934882014, "TRACLEER": 68.62983098871018}
\ No newline at end of file
+{"BUSULFAN": 35.41603743977941, "BYETTA": 20.424036291162206, "OLANZAPINE": 10.230292281644529, "null": 1.637679800270029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8813.json
index b092c25a436..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8813.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8813.json
@@ -1 +1 @@
-{"KEYTRUDA": 14.567657279620676}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8814.json
index e3ce515a360..ff1335d9e84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8814.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8814.json
@@ -1 +1 @@
-{"OLANZAPINE": 12.226337145241295, "SYCREST": 158.27905800056652, "ZYPREXA": 22.635089173349705, "null": 4.783466251645664}
\ No newline at end of file
+{"ASPARAGINASE": 36.922295647503525, "BYETTA": 21.51144230105459, "CELLCEPT": 8.080933591010567, "COMIRNATY": 0.0629671744558782, "CRIXIVAN": 16.038000960695626, "DEXAMETHASONE": 2.108258722557668, "FORXIGA": 6.061924929812348, "JANUMET": 9.832046383073704, "JANUVIA": 18.4426117276304, "JARDIANCE": 7.328855406485429, "MERCAPTOPURINE": 25.46109767435728, "NORVIR": 14.842834958997877, "OLANZAPINE": 5.879422448152801, "ONCASPAR": 142.5177441968473, "PEGASYS": 1.3842625376626398, "PEGINTRON": 1.684539006185121, "SAXENDA": 11.273877099815111, "SPIKEVAX": 0.0910681844724815, "TRULICITY": 6.181048234022347, "VICTOZA": 20.418830244227827, "ZYPREXA": 2.225011387348092, "null": 0.910677053436026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8815.json
index 78d100bb125..d4ba3aaa627 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8815.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8815.json
@@ -1 +1 @@
-{"null": 2.3344495938692265}
\ No newline at end of file
+{"ATRIPLA": 1.0467715868274468, "BYETTA": 46.569648047079085, "JANUVIA": 8.513367501894463, "JARDIANCE": 7.576997027183109, "MEPOLIZUMAB": 25.91031256704573, "STELARA": 3.549986254353587, "ZYPREXA": 4.3143328506515095, "null": 0.7566091598533724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8816.json
index 809c56e8414..8a0304896ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8816.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8816.json
@@ -1 +1 @@
-{"CHAMPIX": 23.47599802790567, "null": 1.7955234614096802}
\ No newline at end of file
+{"JANUVIA": 251.8054739786547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8817.json
index 6afc60a4600..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8817.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8817.json
@@ -1 +1 @@
-{"ARIPIPRAZOLE": 15.918601568440556, "CLOPIDOGREL": 4.88290838968886, "ELIQUIS": 3.867949920595654, "HUMALOG": 4.975809372949913, "ZOSTAVAX": 9.44750254504612}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8818.json
index 56b2ce65777..55b4a8af3b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8818.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8818.json
@@ -1 +1 @@
-{"COMIRNATY": 6.141551440653261, "SPIKEVAX": 3.024007100320395, "TOVIAZ": 8.776479087454058, "VAXZEVRIA": 1.439307430686231}
\ No newline at end of file
+{"null": 0.889013411256888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8819.json
index 51264e0956f..126dce84f9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8819.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8819.json
@@ -1 +1 @@
-{"SUBOXONE": 72.53984025747019, "null": 2.0895536841468973}
\ No newline at end of file
+{"ABACAVIR": 0.6535037290859786, "ABILIFY": 0.3031691548317441, "ABRAXANE": 1.1373758948084116, "ADALIMUMAB": 0.0439393639828752, "ADCETRIS": 3.3333090118730357, "ADCIRCA": 1.4668660362376835, "ADENURIC": 4.300274501970052, "ADVAGRAF": 5.2599519939128365, "AFINITOR": 1.4762318446608835, "ALEMTUZUMAB": 5.058853916693145, "ALIMTA": 19.1483356397338, "ALL": 2.192959408731116, "AMIKACIN": 2.3218026713617226, "AMINOSALICYLIC": 0.7253835072085469, "ANAKINRA": 0.4792724989746103, "ANIDULAFUNGIN": 3.9428006652885976, "APROVEL": 2.5661465954962472, "ARANESP": 2.0216098298546825, "ARAVA": 0.4949756518708546, "ASPARAGINASE": 3.876722608542614, "ATAZANAVIR": 0.7762304928323625, "ATRIPLA": 0.0324782319145347, "AUBAGIO": 0.1167581466981505, "AVANDIA": 0.3543926999259718, "AVASTIN": 1.6787807447325709, "AXICABTAGENE": 7.408489041631926, "AZACITIDINE": 12.151355792967754, "AZATHIOPRINE": 2.867812354105149, "BARACLUDE": 2.9125412406315285, "BASILIXIMAB": 5.230846874129729, "BEDAQUILINE": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/882.json
index aae74a0243f..7fd041d5514 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/882.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/882.json
@@ -1 +1 @@
-{"null": 1.1754565013842662}
\ No newline at end of file
+{"REMICADE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8820.json
index 6ccd8ffb5c9..936ad006981 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8820.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8820.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.27398926473085, "ABRAXANE": 1.901588802020733, "ACETYLSALICYLIC": 4.792868753691911, "ACLASTA": 1.391388731434527, "ACTOS": 1.6125887037871276, "ADCIRCA": 1.1226897742733304, "ADEMPAS": 1.410941990674902, "AFINITOR": 2.5558923235153173, "AGOMELATINE": 2.26619573459899, "AIMOVIG": 1.996916406560152, "ALIGN": 9.531297239540326, "ALL": 1.3931645080069237, "ALOGLIPTIN": 4.626743628226365, "ALPELISIB": 3.1720607052156304, "AMBRISENTAN": 2.920628145350486, "AMIKACIN": 1.393052326723889, "AMINOSALICYLIC": 5.490725383114952, "ANTIBIOTICS": 1.2226322868923645, "APIDRA": 1.6171163279324512, "APREMILAST": 2.161337933005101, "ATAZANAVIR": 1.0960412634482604, "AUBAGIO": 2.1566624206184857, "AVAMYS": 2.7536061956871776, "AVASTIN": 1.0745030718614494, "AVELUMAB": 1.1100722543489854, "AXITINIB": 2.693083637418138, "AYESURBY": 31.288625526700592, "AZATHIOPRINE": 2.8158026776346405, "BEDAQUILINE": 1.856413255066785, "BENLYSTA": 1.9614088648339127, "BENRALIZUMAB": 1.0896427218504483, 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1.41837538432295, "TRESIBA": 1.181179533667093, "TRIUMEQ": 1.482557228248606, "TRULICITY": 6.563915876721717, "VELMETIA": 2.7928500003767067, "VICTOZA": 4.980125964083531, "VOTRIENT": 2.862116427183357, "XALKORI": 1.5995020876440462, "XELJANZ": 1.1070726863659877, "XOFIGO": 2.23881337343016, "XOLAIR": 1.1543252790830991, "XTANDI": 3.365319771544744, "XYREM": 5.238743742022834, "YERVOY": 2.176922518401426, "ZAVESCA": 9.606664910147456, "ZELBORAF": 2.0381982913901044, "ZEPATIER": 1.780527876193712, "ZERIT": 2.0873281334524787, "ZIDOVUDINE": 3.842837775259624, "ZONEGRAN": 4.140551471611718, "ZYCLARA": 1.1549809622457237, "ZYPREXA": 1.1285268364306915}
\ No newline at end of file
+{"ABILIFY": 1.6213057360639187, "AIMOVIG": 2.133760918296724, "ATRIPLA": 0.2856674347093357, "AUBAGIO": 0.491776693290936, "AVANDIA": 0.1902905347742979, "BEDAQUILINE": 0.8428467040236174, "BENLYSTA": 1.075499067529223, "BIKTARVY": 1.0593692987671763, "BRILIQUE": 0.8988255703491379, "BRINTELLIX": 3.246288600003654, "BRIVIACT": 1.6620944591939262, "BUPRENORPHINE": 0.7588284242018452, "CANNABIDIOL": 3.5010844484843004, "CELLCEPT": 0.323941519699214, "CHAMPIX": 10.056562003766496, "CIMZIA": 0.2514158215736366, "CLOPIDOGREL": 0.58566977135189, "COMIRNATY": 0.8941279207577484, "COSENTYX": 0.3813395307167014, "CYMBALTA": 4.366813821248432, "DULOXETINE": 2.337600477742967, "ELIQUIS": 0.3670932856975606, "ELLAONE": 2.076656878830349, "ENTRESTO": 0.3828199776857112, "ESOMEPRAZOLE": 1.23196720151352, "EXFORGE": 0.4545614745643488, "FAMPYRA": 0.7007308427584947, "FASLODEX": 0.4392768413656443, "FORSTEO": 0.5559516586227311, "GARDASIL": 1.8971591912514247, "HUMALOG": 0.7265297965478289, "HUMAN": 1.1703450416435828, "HUMIRA": 1.434629892714314, "IBRANCE": 0.3092648023489642, "IRBESARTAN": 1.4786961451008436, "JANUMET": 0.5841258904441108, "JANUVIA": 0.302524566564105, "KAFTRIO": 2.810369705558496, "KEPPRA": 2.586705929899137, "LANTUS": 0.6388931389323571, "LATUDA": 6.119671745237946, "LEVEMIR": 0.4611471457756033, "LEVETIRACETAM": 0.5689633074872819, "LEVOFLOXACIN": 1.3017376288633231, "LYRICA": 2.857509797062542, "METHOTREXATE": 0.2327066587924321, "MICARDIS": 0.5785512526871547, "NORVIR": 1.2337672633055738, "OCRELIZUMAB": 0.916452154500994, "OLANZAPINE": 1.2274556507232302, "OMALIZUMAB": 0.9958988264064772, "OPSUMIT": 0.3470020263389426, "OXYBUTYNIN": 2.183191114284211, "PANTOPRAZOLE": 0.7881121427271994, "PEGASYS": 1.972902341629219, "PEGINTERFERON": 0.5737345441542477, "PEGINTRON": 1.007002256237549, "PREGABALIN": 1.3021826624867174, "REMICADE": 1.3730023471330397, "SAXENDA": 0.7581867705594053, "SIFROL": 2.224470168023422, "SIMPONI": 0.2992616146129533, "SPIKEVAX": 0.5407446445671634, "STALEVO": 1.6086270020461395, "STELARA": 0.8421334319802346, "SUBOXONE": 2.888542838445511, "TAMIFLU": 2.862934426803805, "TOZINAMERAN": 1.3080389672738473, "TRELEGY": 1.8377414594524577, "TRIUMEQ": 2.3615591326696896, "TRUVADA": 0.078524840686512, "VAXZEVRIA": 0.4494037729425015, "VFEND": 0.377495359351014, "VIAGRA": 0.3462719092384179, "VIMPAT": 1.3508372655550684, "VOTRIENT": 0.4276485470886378, "XELJANZ": 0.3207134349107623, "XOLAIR": 0.4633458832842336, "XTANDI": 0.2972069699441472, "XYREM": 5.907251742015056, "ZOSTAVAX": 0.4536882008774962, "ZYPREXA": 1.5200853772645022, "null": 1.8702077599843312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8821.json
index 7835e5a83ab..fc83a54fe36 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8821.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8821.json
@@ -1 +1 @@
-{"ABILIFY": 5.700783215477451, "ADEMPAS": 14.526967068293562, "BENLYSTA": 8.747155227774906, "BYDUREON": 8.161692824268334, "BYETTA": 10.676920687446904, "CLOPIDOGREL": 1.2878554016876171, "COSENTYX": 1.4712446853846377, "CYMBALTA": 1.1198014889026775, "ELIQUIS": 4.857622923340889, "EMPAGLIFLOZIN": 13.872612103885716, "ENTRESTO": 8.420773088242267, "ENTYVIO": 3.0078092019056752, "FASLODEX": 3.558198188071976, "GARDASIL": 1.2502838645051604, "HIZENTRA": 10.59553145379274, "IBRANCE": 4.347649802845661, "IBUPROFEN": 3.5382713112032005, "JANUMET": 2.751495841908179, "JANUVIA": 5.880919100784312, "JARDIANCE": 1.1079961918318029, "LEVETIRACETAM": 2.1132996425311807, "OPSUMIT": 2.7702913851064896, "REVATIO": 5.0709524258068415, "RUCONEST": 41.670516432440685, "SACITUZUMAB": 118.35994500566149, "SIMPONI": 2.008695320535374, "STELARA": 2.136139222542012, "SUTENT": 5.697457395267292, "TOVIAZ": 7.170977782469854, "VIAGRA": 2.527710865504817, "XELJANZ": 2.109185385587176, "ZOSTAVAX": 2.6375087600136995}
\ No newline at end of file
+{"ABILIFY": 2.139114101318896, "AIMOVIG": 2.361561208923401, "ARIPIPRAZOLE": 5.837888536493575, "BRINTELLIX": 2.404114238993878, "BUPRENORPHINE": 4.884450278241646, "BYETTA": 2.32823854958584, "CHAMPIX": 9.376908754594163, "COMIRNATY": 0.4670368668812328, "CYMBALTA": 3.300174529860593, "GARDASIL": 1.713043935572801, "PEGASYS": 0.6107956418460238, "RISPERIDONE": 15.532924596578226, "SPIKEVAX": 0.1583692026085524, "TOZINAMERAN": 0.5108925894707186, "VAXZEVRIA": 0.1288429599549702, "ZOSTAVAX": 1.9617966715467612, "null": 2.4155310389665097}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8822.json
index 8024ecd70f0..606d7689d98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8822.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8822.json
@@ -1 +1 @@
-{"KEPPRA": 3.042301605675384, "ROTATEQ": 50.16241960286814, "SPINRAZA": 31.273888111899563, "null": 1.6177921842728895}
\ No newline at end of file
+{"ABILIFY": 8.74408217567114, "AIMOVIG": 0.9889962823361864, "BRINTELLIX": 2.618845466786256, "CHAMPIX": 10.437362256158758, "COMIRNATY": 0.540587238603271, "CYMBALTA": 2.249261245525911, "HUMALOG": 0.9995226610282466, "KEPPRA": 1.1891708793483418, "LANTUS": 0.5170482090775229, "LATUDA": 3.1106919729643723, "OMALIZUMAB": 1.7782264234822691, "PEGASYS": 0.7374164196370558, "SPIKEVAX": 0.3263790248921767, "TAMIFLU": 3.8643770514106337, "TOZINAMERAN": 1.5416990719815424, "VAXZEVRIA": 0.2725754033711241, "VIAGRA": 2.983754783082659, "ZYPREXA": 1.307835246667177, "null": 2.52646466388135}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8823.json
index 6293b41225a..6dbc9009b22 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8823.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8823.json
@@ -1 +1 @@
-{"ABASAGLAR": 4.88030913240921, "ABATACEPT": 3.222054334476333, "ABILIFY": 9.858281419258695, "ACLIDINIUM": 4.775470346259801, "ACTOS": 6.6466406298862, "ADEMPAS": 2.596112598162445, "ADENURIC": 1.765758049933342, "AGOMELATINE": 4.625625762765139, "AIMOVIG": 3.2878357991115723, "ALL": 1.2640509269336704, "ALLI": 4.076698886255223, "AMBRISENTAN": 3.97229738675915, "ANAKINRA": 1.3916460903825896, "APIDRA": 3.0033977762618456, "ARIPIPRAZOLE": 8.56854107266457, "AVANDAMET": 1.94329353972283, "AVANDIA": 4.012559569934552, "AZTREONAM": 1.41038639415938, "BARACLUDE": 1.0370598747374322, "BENLYSTA": 1.8208273457315576, "BIKTARVY": 24.17852742027715, "BOSULIF": 1.673878213661428, "BREXPIPRAZOLE": 3.382896809196199, "BRINTELLIX": 4.703587653345733, "BRIVARACETAM": 4.52689709748678, "BRIVIACT": 1.833378160563276, "BUMETANIDE": 1.557591451610952, "BUSILVEX": 1.1034238916205807, "BYDUREON": 2.039368076335262, "BYETTA": 1.8787117619991551, "CAPSAICIN": 22.949900014465992, "CHAMPIX": 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\ No newline at end of file
+{"ABATACEPT": 7.336970830511453, "ADALIMUMAB": 8.630576811801054, "ALIMTA": 3.682938896503301, "APREMILAST": 53.17751302090653, "ARAVA": 2.2656017628602823, "ASPARAGINASE": 4.642960968138163, "BETAFERON": 13.03687385137447, "CICLOSPORIN": 5.907184514318056, "CIMZIA": 1.071883087378343, "COMIRNATY": 0.2177050200998406, "COTELLIC": 34.98819975996297, "DABRAFENIB": 33.217689177885575, "ENBREL": 57.766475810893695, "FORSTEO": 1.66442988896085, "INCIVO": 4.639197831916441, "KEYTRUDA": 1.0779882885727574, "MEKINIST": 33.111360553567046, "ROACTEMRA": 5.676562605370352, "SOMATROPIN": 25.471415284247072, "VAXZEVRIA": 0.0535455204439643, "VEMURAFENIB": 79.29499705804155, "ZELBORAF": 17.593938575093958, "null": 0.2698694901082479}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8824.json
index d46dab4e0af..c362372d9bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8824.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8824.json
@@ -1 +1 @@
-{"BIKTARVY": 14.856736575321465, "HUMALOG": 1.8936786064205209, "INSULIN": 4.223975719980431, "LYRICA": 3.929569603194068, "SAXENDA": 965.4894508152456, "VICTOZA": 24.623886041282034}
\ No newline at end of file
+{"null": 0.7764183008908029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8825.json
index 39d571ee70a..ed0925539dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8825.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8825.json
@@ -1 +1 @@
-{"null": 1.8116090308198636}
\ No newline at end of file
+{"null": 7.991404633395833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8826.json
index 05c7e2e77e4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8826.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8826.json
@@ -1 +1 @@
-{"CICLOSPORIN": 40.44515392850197}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8827.json
index e8b3e1ad9f4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8827.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8827.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.678100267348685, "ANAKINRA": 7.153326826585732, "APIDRA": 6.771274412636358, "ARAVA": 1.6336237556521116, "AUBAGIO": 8.835778045538053, "CIMZIA": 2.246067767444204, "ENBREL": 3.1094182321428505, "FIRDAPSE": 12.285128043700904, "GARDASIL": 5.163870363645093, "LANTUS": 12.950056083919891, "LEVEMIR": 5.280469474473868, "MEPOLIZUMAB": 16.213593498519252, "OPTIMARK": 9.718743097686168, "PANTOPRAZOLE": 7.979754646464273, "XELJANZ": 1.602848544166797}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8828.json
index 1d4f27d965e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8828.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8828.json
@@ -1 +1 @@
-{"ACLIDINIUM": 29.2749140088134, "ADALIMUMAB": 1.0368796770402404, "ADCIRCA": 1.605318985988665, "ALOXI": 4.280106120179919, "AMBRISENTAN": 2.1237616544143507, "ANORO": 5.525215327544076, "ANTIHYPERTENSIVES": 11.781719784092292, "APIXABAN": 13.498227550798324, "AVAMYS": 16.320894925417466, "AZOPT": 3.089160737706595, "BENRALIZUMAB": 46.69890690254191, "BORTEZOMIB": 1.4554279337017952, "BRIDION": 3.979043850495192, "BUDESONIDE": 16.163702002149996, "CANAGLIFLOZIN": 13.058257671473092, "CARFILZOMIB": 1.1694017500223086, "CAYSTON": 66.6516543865157, "CELECOXIB": 1.5192571076674424, "CHOLESTAGEL": 13.887793868514253, "COSENTYX": 1.0662091837037566, "DARZALEX": 2.8702297832722103, "DAXAS": 30.30733704577424, "DESLORATADINE": 9.892101836178927, "DEXAMETHASONE": 1.1921480132755065, "DINUTUXIMAB": 10.335886914533916, "DOVATO": 6.495459550206273, "DUAKLIR": 15.941440210298564, "DUORESP": 5.809949516841132, "DUPIXENT": 5.745217013665631, "FASENRA": 7.998850976150823, "FENTANYL": 1.1399850510140286, "FLEBOGAMMA": 3.5015311649235485, "FLUTICASONE": 23.597266514544344, "GLYCOPYRRONIUM": 41.11811373712996, "HIZENTRA": 1.848050637977571, "HYDROCORTISONE": 3.379292472098378, "INCRUSE": 10.93278925054894, "INSULIN": 2.13265936460401, "IRBESARTAN": 1.0344528818016971, "IRON": 3.3635869350630774, "KALYDECO": 1.5016161338740388, "KIOVIG": 1.5888784161971452, "LEVOFLOXACIN": 1.0836993990420187, "LIRAGLUTIDE": 37.35591879695957, "MEPOLIZUMAB": 42.67550950733181, "MULTAQ": 1.6562821550165343, "NAGLAZYME": 1.4715839809318747, "NUCALA": 37.915359059490925, "OMALIZUMAB": 20.961389587881644, "ONCASPAR": 1.3161867913970704, "ORKAMBI": 2.113947201904041, "PANTOPRAZOLE": 5.52654720712097, "PREVENAR": 1.4953416014413698, "PRIVIGEN": 3.193760137988662, "RELVAR": 5.819673347343997, "RITUXIMAB": 2.3492137366699177, "RIVAROXABAN": 1.704023568387718, "SEEBRI": 8.824417980937305, "SYNAGIS": 9.469260714909668, "TELMISARTAN": 5.55756358154325, "TOBI": 9.034577800287948, "TOBRAMYCIN": 1.840201565959904, "TRELEGY": 4.442134593427112, "UMECLIDINIUM": 27.58890843966702, "XOLAIR": 12.40408352587772, "null": 1.1188148904704156}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8829.json
index c74976aef68..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8829.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8829.json
@@ -1 +1 @@
-{"ADALIMUMAB": 9.21635320977166}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/883.json
index d3fda8a1c5d..07d7b04b186 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/883.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/883.json
@@ -1 +1 @@
-{"null": 8.263762588330993}
\ No newline at end of file
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8830.json
index ca700eed701..7be1b5925a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8830.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8830.json
@@ -1 +1 @@
-{"COVID19": 2.364097095826074}
\ No newline at end of file
+{"PANTOPRAZOLE": 170.1968268076687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8831.json
index 50faea35af1..3cf5b6be4ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8831.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8831.json
@@ -1 +1 @@
-{"ABATACEPT": 5.242781843671874, "ARAVA": 14.849201187849102, "AZACITIDINE": 14.751921149380658, "BEVACIZUMAB": 3.17015856026532, "BOSULIF": 8.28320962830743, "CYMBALTA": 1.6742424379334035, "CYTARABINE": 6.951199444951618, "FASLODEX": 3.0729492724908445, "IBRANCE": 14.034120436953607, "JAKAVI": 4.445374356989444, "LEFLUNOMIDE": 8.77558783836773, "LEMTRADA": 9.3182022126485, "NEULASTA": 86.49372363947388, "PEGASYS": 3.66934892534104, "PEGINTRON": 3.894777321082533, "PLEGRIDY": 6.085504510925958, "SOLIRIS": 2.6088109657321885, "SPRYCEL": 3.2217981393792985}
\ No newline at end of file
+{"BYETTA": 76.32777601954106, "CICLOSPORIN": 11.107906295265762, "COSENTYX": 3.11699762734238, "ESOMEPRAZOLE": 59.17053071577792, "NEXAVAR": 9.220969723878095, "SAXENDA": 22.8405449442475, "SIMPONI": 4.136550145026031, "TRULICITY": 6.215948186476563, "VICTOZA": 79.29206029468016, "null": 0.6944550782546876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8832.json
index 63e96541f5a..abe275d765b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8832.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8832.json
@@ -1 +1 @@
-{"ABEMACICLIB": 3.8952560166661834, "ABRAXANE": 2.5571074605085102, "ADCETRIS": 5.397435728311549, "AFINITOR": 1.1382610247143348, "ALIMTA": 3.7213138808959054, "ARIPIPRAZOLE": 1.0859050871839615, "ASPARAGINASE": 1.0927360741236012, "ATEZOLIZUMAB": 2.5637776412844078, "AUBAGIO": 1.1561586632120768, "AVASTIN": 6.900969549396407, "AXICABTAGENE": 2.602999876440353, "AZACITIDINE": 6.574248365810278, "BARACLUDE": 1.2682904665388754, "BEDAQUILINE": 1.067713262980436, "BEVACIZUMAB": 6.617793594097158, "BOCEPREVIR": 2.1123775493664323, "BORTEZOMIB": 1.5816001847792576, "BOSULIF": 1.6570183248496169, "BRENTUXIMAB": 11.319192895109182, "BREYANZI": 4.661951063207062, "BRUKINSA": 4.685050467870497, "CABAZITAXEL": 1.0150475083669632, "CANCIDAS": 3.100931658773742, "CAPECITABINE": 6.321392784495624, "CASPOFUNGIN": 1.2482682076133975, "CELECOXIB": 2.3331872587715963, "CELLCEPT": 2.2764420439661515, "CETUXIMAB": 4.273753045488423, "CLADRIBINE": 2.105249887368532, "CRESEMBA": 1.183296651371562, "CYTARABINE": 3.771167868541916, "DACOGEN": 7.00772534734014, "DARATUMUMAB": 1.9684240676191331, "DARZALEX": 3.266587948801061, "DASATINIB": 1.9782450158097948, "DECITABINE": 4.757543114170407, "DENOSUMAB": 1.6064504046374537, "DEXAMETHASONE": 1.9867730017307812, "DEXRAZOXANE": 19.313771244146363, "DOCETAXEL": 23.808916684689176, "DOXORUBICIN": 18.209014711799416, "ELTROMBOPAG": 3.109382470609565, "EMEND": 2.7750883331793195, "ENTECAVIR": 1.0202963128674674, "EPIRUBICIN": 50.06382320888917, "EPOETIN": 1.1288495146930253, "ERBITUX": 17.198878663573115, "ERIBULIN": 8.747986864174766, "ERLEADA": 1.0388461524892327, "EXJADE": 1.938183685980066, "FASLODEX": 5.9082204564764655, "FEBUXOSTAT": 1.6885880515707914, "FILGRASTIM": 3.775530833965232, "FULVESTRANT": 4.07136591133085, "GANCICLOVIR": 4.441414615500608, "GAVRETO": 8.64198337776074, "GAZYVARO": 3.625977881056468, "GILENYA": 3.035252966684209, "GLIVEC": 3.2449237429848106, "HALAVEN": 14.261058894477518, "HERCEPTIN": 6.7191966983459785, "HYCAMTIN": 24.24588415432542, "IBRANCE": 20.23655126051729, "IBRUTINIB": 1.6638881232579192, "ICLUSIG": 1.5938302402067728, "IMBRUVICA": 1.507138426794918, "INCIVO": 1.8192102915877704, "INFERGEN": 5.945902781266676, "INTERFERON": 3.9589913980705234, "INTRONA": 3.940577973735394, "IRBESARTAN": 1.0753419424424906, "IRESSA": 1.160425981225886, "IRINOTECAN": 3.281021485433438, "JAKAVI": 2.4896111222027724, "JEVTANA": 5.9411736485686095, "KESIMPTA": 1.0103727550545465, "KEYTRUDA": 1.0865394957426613, "KISQALI": 5.314712591094712, "KYMRIAH": 2.96821724130266, "KYPROLIS": 2.320966858333112, "LEFLUNOMIDE": 2.102669778422348, "LEMTRADA": 1.363417665815822, "LENALIDOMIDE": 5.487689980223721, "LENVIMA": 1.4183475802047427, "LEVOFLOXACIN": 1.0833491372343906, "LONSURF": 6.711295721444728, "LUTATHERA": 1.3365387122958876, "LYNPARZA": 3.803987908531559, "MABTHERA": 18.83444965643559, "MANNITOL": 2.602616067140603, "MAVENCLAD": 5.205688873491689, "MERCAPTOPURINE": 8.45404145884898, "METFORMIN": 1.544820306841603, "METHOTREXATE": 2.144316456136059, "NEULASTA": 7.939298802822751, "NEXAVAR": 1.4314339020767337, "NINLARO": 4.675813905010871, "NIVOLUMAB": 2.8638986780071414, "OBINUTUZUMAB": 3.640182497062746, "OLANZAPINE": 1.855212137632595, "OLAPARIB": 3.089787173753777, "OPDIVO": 1.159375524680179, "OSELTAMIVIR": 1.330361942254704, "PACLITAXEL": 16.075427350488546, "PEGASPARGASE": 8.112431180730317, "PEGASYS": 14.329082505493377, "PEGFILGRASTIM": 4.027264239750097, "PEGINTERFERON": 3.2334232606248388, "PEGINTRON": 5.453411006971207, "PEMETREXED": 7.598839570149743, "PERJETA": 5.92307378257393, "PERTUZUMAB": 4.636403099802152, "PIOGLITAZONE": 14.337367824150247, "PLEGRIDY": 1.940995234696184, "REVLIMID": 5.201440902574529, "REVOLADE": 8.223192164994446, "RIBAVIRIN": 1.1946631918717077, "RIBOCICLIB": 5.349684788091665, "RITUXIMAB": 9.566078493125795, "ROACTEMRA": 1.517958120743394, "RUBRACA": 4.619791886356677, "RUXOLITINIB": 1.7491920435875157, "SCEMBLIX": 3.248883719516391, "SOLIRIS": 1.161654389584924, "SPRYCEL": 1.957372462556019, "STIVARGA": 1.1126528766219004, "SUTENT": 2.9915391305018275, "TAGRISSO": 1.8339529324205328, "TAMIFLU": 1.5281443708837077, "TASIGNA": 1.6574109083982471, "TAXOTERE": 15.763995605032802, "TEGAFUR": 32.39378602539339, "TEMODAL": 4.699609438640698, "TEMOZOLOMIDE": 1.738798274808997, "TEMSIROLIMUS": 2.618507955041384, "TISAGENLECLEUCEL": 12.273883794568777, "TISLELIZUMAB": 40.15888725408857, "TOCILIZUMAB": 1.8479724215991733, "TOPOTECAN": 8.70243420292299, "TRASTUZUMAB": 4.2711855442322015, "TRISENOX": 1.7015598481539682, "TRODELVY": 1.03738649018032, "VECTIBIX": 1.7702140587743909, "VELCADE": 2.298869246355656, "VENCLYXTO": 1.503409935464156, "VENETOCLAX": 3.4359587230461583, "VFEND": 1.2530033631203032, "VIDAZA": 3.5284308059266656, "XELODA": 12.905969957567365, "XOFIGO": 3.423085248372752, "ZEJULA": 1.9259753815324243, "ZEVALIN": 22.088116770801957, "ZIAGEN": 1.1348134137850114, "ZOMETA": 1.7795801563707727, "null": 1.4318307223751496}
\ No newline at end of file
+{"null": 0.5789208692211475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8833.json
index fec0ff40d72..6be2e7863bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8833.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8833.json
@@ -1 +1 @@
-{"AFINITOR": 1.1065704447571012, "ALIMTA": 1.0495570039744884, "AMINOSALICYLIC": 4.48143174191488, "APREPITANT": 1.563889770702202, "ARIPIPRAZOLE": 2.2014333628548237, "AZACITIDINE": 1.478472559926293, "BEDAQUILINE": 14.275342261473712, "BEVACIZUMAB": 1.3820752679442367, "BOSULIF": 5.445098163171418, "BRUKINSA": 10.605860697292952, "CANCIDAS": 7.748932073997253, "CAPECITABINE": 1.419904920303715, "CARFILZOMIB": 1.826948144294039, "CELLCEPT": 1.5537338828708496, "CICLOSPORIN": 1.4575353999501548, "CLOPIDOGREL": 1.5866525527526203, "COMTAN": 1.6376605198867702, "CUBICIN": 3.0048177534827345, "CYTARABINE": 1.3144985519444323, "DASATINIB": 4.24484686144784, "DELAMANID": 2.3241128681456606, "DEXAMETHASONE": 1.6050735569421493, "DIFICLIR": 10.662089775455318, "DOCETAXEL": 2.0993060115055737, "DOXORUBICIN": 1.9496910481689045, "EMEND": 3.443732354418665, "ENTYVIO": 1.6209537082425145, "EVISTA": 1.4172308191042684, "EXJADE": 6.888005128195317, "FAMPYRA": 1.2025469839019312, "FASLODEX": 1.0060710249007538, "FILGRASTIM": 6.608190500451387, "GLIVEC": 7.808149539327949, "HUMIRA": 1.922496143558521, "IBRANCE": 1.016387442190864, "ICLUSIG": 2.877764765817604, "IMATINIB": 5.744098437062779, "IMBRUVICA": 4.255781463990515, "INFLIXIMAB": 1.7334487941503165, "JAKAVI": 21.374728181539915, "JEVTANA": 2.412244413109325, "KEYTRUDA": 1.4179823563024627, "KYMRIAH": 2.6052933391243687, "LATUDA": 1.1667595643673394, "LEMTRADA": 3.9596133054999454, "LENVIMA": 1.331340101329986, "LEVOFLOXACIN": 1.6706724063310483, "LYRICA": 1.169149686617195, "MEKINIST": 1.002415235406888, "METHOTREXATE": 1.2984935775381092, "NEULASTA": 11.990640951596411, "NILOTINIB": 3.852166419725144, "NPLATE": 4.054179709338397, "OLANZAPINE": 3.8552802304920464, "OLYSIO": 2.056386271795356, "OPSUMIT": 1.5860459318572473, "PIOGLITAZONE": 6.863550994172742, "PROTELOS": 6.890425586572335, "REMICADE": 2.5164782502941474, "RINVOQ": 1.8629149070344493, "RITUXIMAB": 1.0691557124602031, "RUXOLITINIB": 14.502731502832216, "SOLIRIS": 1.8332516812826465, "SPRYCEL": 3.625381617941589, "STELARA": 1.5399747617175092, "STIVARGA": 1.34592429749842, "TAMIFLU": 1.3016649944932308, "TASIGNA": 7.075524074978095, "TOBRAMYCIN": 4.034530455565668, "TORISEL": 1.8429560994243712, "TRACLEER": 1.6404299408675862, "TREMFYA": 1.9000073631410856, "TRISENOX": 9.473695475307954, "VENCLYXTO": 4.470997287546172, "VENETOCLAX": 3.7827634789895215, "VFEND": 1.210502730694598, "VORICONAZOLE": 1.2030659278304832, "XELJANZ": 1.4793221663276614, "XOLAIR": 2.229889542836527, "ZONISAMIDE": 6.168997813084316, "ZYPADHERA": 1.6188868721972247, "ZYPREXA": 2.9695551534584075, "null": 1.5821488293029629}
\ No newline at end of file
+{"AMINOSALICYLIC": 3.65535516676802, "ARAVA": 0.3959149080543565, "ASPARAGINASE": 3.28688134670332, "BEOVU": 17.215404632937354, "CICLOSPORIN": 4.095629597089677, "CIMZIA": 0.742007999005774, "COMIRNATY": 0.3998930704533603, "DOXORUBICIN": 8.555582261201163, "GARDASIL": 1.5970441244572195, "KAFTRIO": 19.14009688655715, "KEPPRA": 1.553834754378539, "KEYTRUDA": 0.8200242890788766, "LEVETIRACETAM": 1.4599275041913884, "MEKINIST": 4.666101138623208, "MULTAQ": 4.683874972733009, "OLANZAPINE": 1.0151891038579604, "OMNITROPE": 46.948165393100005, "PEGASYS": 2.7331147756334957, "PEGINTRON": 6.061506012587965, "SOMATROPIN": 23.66846701604428, "SPIKEVAX": 0.2085633256701773, "STELARA": 0.9056962438372936, "SUTENT": 0.4112328432502679, "TASIGNA": 2.919336754881121, "TESTOSTERONE": 18.124087432693496, "TOZINAMERAN": 0.3169364206253693, "VAXZEVRIA": 0.1921222787208765, "VFEND": 9.290576519719766, "VIAGRA": 5.251589461528071, "XOLAIR": 1.0390422537131203, "null": 1.4173241944853638}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8834.json
index f76c4cc3b3c..b21d5bb8fa3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8834.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8834.json
@@ -1 +1 @@
-{"SPIKEVAX": 30.033412621196096}
\ No newline at end of file
+{"COMBIVIR": 118.6214886852543, "null": 0.4380007937505467}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8835.json
index 20a34166697..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8835.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8835.json
@@ -1 +1 @@
-{"IBRANCE": 7.523910379794159, "JAKAVI": 9.01802196483206, "KEPPRA": 1.769920925770968, "NEULASTA": 28.4043541912802, "PEGASYS": 7.37444050070655, "SUTENT": 1.6320141157395254}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8836.json
index c14f1f3e2b3..ae9b1e51dc6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8836.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8836.json
@@ -1 +1 @@
-{"ADENURIC": 59.34975512620794, "ALEMTUZUMAB": 37.20566405736726, "BEDAQUILINE": 23.73431312126392, "LEMTRADA": 25.18015973754559}
\ No newline at end of file
+{"CICLOSPORIN": 5.25570815753891, "CIMZIA": 2.157452691048843, "COMIRNATY": 0.2593372676580348, "GARDASIL": 136.76112806333907, "RINVOQ": 6.657472651351819, "SILGARD": 421.0598913020565, "SIMPONI": 4.77743216925028, "STELARA": 8.282255156402226, "null": 0.2443770724992296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8837.json
index 03d31285215..a0fcd2029c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8837.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8837.json
@@ -1 +1 @@
-{"COVID19": 1.198204007083551}
\ No newline at end of file
+{"AFINITOR": 0.841379410371781, "AIMOVIG": 1.2769388218032285, "APIDRA": 1.160003144681174, "ARAVA": 0.1069392733449812, "BRIDION": 2.642221573526292, "BUDESONIDE": 0.6294480224457456, "CICLOSPORIN": 2.893337769684968, "CLOPIDOGREL": 0.6172328383037953, "COMIRNATY": 0.542631947727726, "COSENTYX": 4.10007667521665, "DESLORATADINE": 6.877681052032816, "DEXAMETHASONE": 1.05957318810989, "ENTRESTO": 0.6513890648644016, "LAMIVUDINE": 4.64319458223776, "LEVETIRACETAM": 0.917587870938166, "LEVOFLOXACIN": 2.499145438150544, "MEPOLIZUMAB": 1.933704372073143, "METFORMIN": 4.364007459109607, "METHOTREXATE": 0.8839275880414295, "MMRVAXPRO": 2.9653925426285235, "MYCOPHENOLATE": 3.662419762310765, "NEXAVAR": 0.3813452183423776, "OLANZAPINE": 0.7892813228579965, "OMALIZUMAB": 2.25199199503836, "OPTIMARK": 3.125187504547718, "PEGINTERFERON": 2.158713462508949, "RINVOQ": 2.0210288182134826, "SHINGRIX": 0.9658672799213036, "SPIKEVAX": 0.5373784499806821, "STELARA": 0.4053478729133964, "STIVARGA": 0.8992848075781855, "SUTENT": 0.1452583063175655, "TOZINAMERAN": 0.380812283611646, "VAXZEVRIA": 0.2756493341084025, "XOLAIR": 1.9276009364716884, "ZOSTAVAX": 1.0258003718130844, "null": 2.852470391718396}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8838.json
index d8d84e9bab5..36157ba22e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8838.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8838.json
@@ -1 +1 @@
-{"CYTARABINE": 46.76206415659838, "HUMIRA": 10.186417692743928, "LACOSAMIDE": 91.1754273084334}
\ No newline at end of file
+{"OPSUMIT": 64.49354821397262, "TRACLEER": 31.727211363231174, "null": 1.3570988604545124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8839.json
index a13f8edacec..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8839.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8839.json
@@ -1 +1 @@
-{"COMIRNATY": 1.9729914387702991}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/884.json
index 95cf9c79840..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/884.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/884.json
@@ -1 +1 @@
-{"ALIMTA": 8.5834952554688, "AMINOSALICYLIC": 6.118621922607735, "CELLCEPT": 8.36955315532905, "DOCETAXEL": 24.46520389994795, "DOXORUBICIN": 23.31936433438412, "JANUMET": 3.87294134869196, "MABTHERA": 13.29593638447238, "METHOTREXATE": 2.3911908765952847, "PLAVIX": 1.6016763079453662, "RITUXIMAB": 23.16369151093126, "null": 1.473315143755655}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8840.json
index c12c9974c84..6aac0677c1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8840.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8840.json
@@ -1 +1 @@
-{"SIMPONI": 25.204321894204767}
\ No newline at end of file
+{"EYLEA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8841.json
index 15574012c4f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8841.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8841.json
@@ -1 +1 @@
-{"null": 4.406448101978552}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8842.json
index fee8ed0b688..87875cac5ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8842.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8842.json
@@ -1 +1 @@
-{"COMIRNATY": 1.2049177516613927, "null": 3.082193078384861}
\ No newline at end of file
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8843.json
index e511177c831..a0d068a1f03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8843.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8843.json
@@ -1 +1 @@
-{"MANNITOL": 843.2177030145225, "null": 2.277577993366569}
\ No newline at end of file
+{"ADALIMUMAB": 0.9572923597366582, "AIMOVIG": 52.12798232262707, "ARIPIPRAZOLE": 5.961315765377827, "CIMZIA": 1.1185461569354884, "COSENTYX": 4.45088973969223, "DEXAMETHASONE": 5.081279787743528, "EFAVIRENZ": 34.394895656535255, "ERENUMAB": 303.9100530685184, "LEVETIRACETAM": 6.250227453284563, "LEVOFLOXACIN": 3.200853529403504, "LURASIDONE": 98.99268137396714, "MIDAZOLAM": 32.845014609609585, "OLANZAPINE": 1.496380677804745, "SIMPONI": 4.524261988290436, "STELARA": 1.192850884706928, "null": 1.942781220693424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8844.json
index 5af49917a86..acfe7238125 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8844.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8844.json
@@ -1 +1 @@
-{"ABILIFY": 1.0420552274131518, "ARIPIPRAZOLE": 1.0903845481176735, "BENZODIAZEPINE": 5.511732148399275, "BREXPIPRAZOLE": 36.616543468221806, "BRINTELLIX": 3.2685492571098336, "BUPIVACAINE": 6.501143882900596, "BUPRENORPHINE": 12.966031460338863, "BUVIDAL": 60.19141039914823, "CANNABIDIOL": 3.01035476977939, "CAPSAICIN": 17.252122727912, "CARIPRAZINE": 13.889161987240223, "CHAMPIX": 4.110460527981488, "CRIXIVAN": 1.842084945619452, "CYMBALTA": 9.560767610940456, "DEXDOR": 16.982351414976133, "DEXMEDETOMIDINE": 15.243475168220606, "DULOXETINE": 1.618353866331426, "FENTANYL": 4.755818931081166, "JAKAVI": 2.076852313926953, "KEPPRA": 1.064858042349897, "LATUDA": 3.3743231697275164, "LEVODOPA": 4.537739524851074, "LURASIDONE": 16.10687412437745, "LYRICA": 7.04597262515944, "MIDAZOLAM": 4.036457781618344, "NALMEFENE": 86.23155975683488, "NOT": 1.957847405913912, "OLANZAPINE": 2.71668153838363, "OXYBUTYNIN": 2.3781146169863603, "POPPERS": 18.629403926374323, "PREGABALIN": 7.906637350333737, "PRIALT": 15.497529369547182, "RISPERIDONE": 1.829019366326052, "RUXOLITINIB": 2.190008556525572, "SELINCRO": 146.44392034752178, "SIFROL": 4.069195062798588, "SUBOXONE": 7.576035229295479, "SUFENTANIL": 2.6950279545415987, "TOVIAZ": 1.6195953203522448, "XYREM": 1.8871868096057307, "ZYPREXA": 2.3421312800579845, "null": 5.768568903432912}
\ No newline at end of file
+{"null": 2.386097647336676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8845.json
index efc6514774b..65aeaafe75a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8845.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8845.json
@@ -1 +1 @@
-{"null": 1.6231736958796046}
\ No newline at end of file
+{"CIMZIA": 26.15177672994138, "COSENTYX": 28.833297118284246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8846.json
index 3c2d618797b..ae5366d2868 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8846.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8846.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.4510006868617524, "ABATACEPT": 6.754910648109536, "ABILIFY": 5.417214867592367, "ADALIMUMAB": 13.090026825490408, "ALDARA": 6.545652792468006, "APREMILAST": 2.428873212538081, "ARAVA": 42.467593812004566, "BENLYSTA": 3.1494979883392635, "CIMZIA": 1.907564596089524, "COSENTYX": 1.272770447196036, "FIRDAPSE": 1.6653631889667275, "FULVESTRANT": 1.902110638000324, "HUMALOG": 1.3413317232234, "IBRANCE": 1.0890732659932274, "ILARIS": 27.975798807876608, "JARDIANCE": 1.0230827067936683, "LEFLUNOMIDE": 2.1858146496035933, "MELATONIN": 1.534837073427506, "MEPOLIZUMAB": 1.5361778416865108, "OPTIMARK": 1.137336578749013, "REMICADE": 1.8887460950211727, "RITUXIMAB": 1.023053654137987, "SIMPONI": 1.4265597693524346, "SUTENT": 2.439009887370276, "VOTRIENT": 1.18296678959667, "XELJANZ": 1.12070846720556, "ZYCLARA": 7.660046100007945}
\ No newline at end of file
+{"ABACAVIR": 0.068199480438112, "ABASAGLAR": 0.4640112406148441, "ABATACEPT": 0.1721989455446701, "ABILIFY": 0.1415572561351614, "ADALIMUMAB": 0.2638653536899454, "ADCIRCA": 0.1792912921083092, "ADENURIC": 0.7526427917382675, "ADVAGRAF": 0.6066126475790827, "AERIUS": 0.3418586768697189, "AFINITOR": 0.1020828387325964, "AIMOVIG": 2.330864443393561, "AJOVY": 3.029568500740866, "ALDARA": 0.7893129074830055, "ALEMTUZUMAB": 0.4340246322754931, "ALIMTA": 0.2786038666574141, "ALOXI": 1.283378532719898, "AMBRISENTAN": 0.4636297450706758, "AMIKACIN": 0.5082649063998524, "AMINOSALICYLIC": 0.0660505386468381, "ANAGRELIDE": 2.3405870967337536, "APIDRA": 0.28809855893443, "APIXABAN": 0.176664966047185, "APREMILAST": 0.3377869784722909, "APREPITANT": 0.1240127840244466, "APROVEL": 0.5858213374757819, "ARANESP": 0.1115121084947882, "ARAVA": 0.2533501884740363, "ATAZANAVIR": 0.1434030041510471, "ATRIPLA": 0.013347238313783, "AUBAGIO": 3.2014366368189435, "AVAMYS": 0.668324857384548, "AVANDIA": 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0.5853420094999183, "ZYPADHERA": 0.2779408144266775, "ZYPREXA": 0.1894255541663795, "null": 0.6148967733611685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8847.json
index 12fddf4f218..ab4cd5b230c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8847.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8847.json
@@ -1 +1 @@
-{"ABILIFY": 30.55285461905696, "ADALIMUMAB": 2.285272100546647, "HUMALOG": 2.2373073071702367, "HUMIRA": 11.67614370224807, "IBRANCE": 2.065868311439693, "NEXOBRID": 689.5894839996491, "SIMPONI": 4.269209330935535, "SUTENT": 4.933854576239964}
\ No newline at end of file
+{"COMIRNATY": 1.4272958652543126, "VAXZEVRIA": 0.6234809346091592, "null": 1.758708352415367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8848.json
index 57f663889dc..ef72d635757 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8848.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8848.json
@@ -1 +1 @@
-{"AVASTIN": 15.963747807507271, "BEVACIZUMAB": 35.20135165165497, "CELLCEPT": 6.658772755013069, "CICLOSPORIN": 3.423193442333331, "FAMPRIDINE": 210.17914583594228, "HUMIRA": 6.408743296619674, "IRON": 40.43915961189301, "KEPPRA": 7.564837726083727, "NEXAVAR": 3.5971583132565668, "SUTENT": 4.327304024824957, "TOVIAZ": 28.50521307785547}
\ No newline at end of file
+{"COMIRNATY": 0.350735027041586, "SPIKEVAX": 0.9495015955939322, "null": 3.0578252712192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8849.json
index 5b809f9a164..d79296bd0ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8849.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8849.json
@@ -1 +1 @@
-{"TOVIAZ": 169.6004886034721, "null": 1.484977119915706}
\ No newline at end of file
+{"ABASAGLAR": 1.2199481677469568, "ADALIMUMAB": 4.871001672239942, "AIMOVIG": 0.685441101248631, "ALIGN": 48.55558979401639, "AMINOSALICYLIC": 24.09811691262469, "AUBAGIO": 0.2629758571109831, "AVAMYS": 13.36010884439316, "AVASTIN": 0.3106225624464568, "BRINTELLIX": 0.3804732691111786, "BUDESONIDE": 16.546404386972316, "BYDUREON": 0.4593925114743045, "CHAMPIX": 0.5417418727559488, "CIMZIA": 0.1209314259450019, "COMIRNATY": 2.010737407306614, "COSENTYX": 0.200060640197204, "CYMBALTA": 0.2260460199178147, "DARZALEX": 0.5741086632929181, "DESLORATADINE": 2.014524297634052, "ELIQUIS": 0.0797603885044383, "ENTRESTO": 0.6394828193893443, "ENTYVIO": 0.5741945131014875, "EVENITY": 0.7828097827285626, "EXFORGE": 0.340450430631437, "FASENRA": 0.9911107149502222, "FASLODEX": 0.3289895638408994, "FENTANYL": 0.6527665875979296, "FIRDAPSE": 15.399609317702334, "FORSTEO": 0.3482050481749253, "GARDASIL": 0.3884913945778258, "HIZENTRA": 0.594879172883376, "HUMALOG": 0.1583324793017441, "HYDROCORTISONE": 1.035814697503211, "IBRANCE": 0.1917699914205878, "INSULIN": 0.3450282006861844, "IRINOTECAN": 0.8950739154684313, "JARDIANCE": 0.1136623713643977, "KEPPRA": 0.0958324691236625, "LANTUS": 0.2626748713622601, "LEVOFLOXACIN": 0.2836820122257347, "MISOPROSTOL": 19.61731223106112, "MODERNA": 0.5431106141447555, "NIMENRIX": 0.5228665778687681, "OMALIZUMAB": 0.5979585000070924, "PEGASYS": 0.0701227968668189, "PREGABALIN": 7.500660612930214, "PRIVIGEN": 0.9261898756345522, "ROACTEMRA": 0.2881011269857193, "SHINGRIX": 0.4998659179056513, "SPIKEVAX": 0.7883835477213269, "STELARA": 0.5129929955772753, "SUTENT": 0.278516547750512, "SYCREST": 5.346089278198875, "TAMIFLU": 0.528677347232487, "TOZINAMERAN": 2.6032653921248725, "TWINRIX": 0.7488961754684834, "VAXZEVRIA": 1.0719333969818157, "XELJANZ": 0.1659806624846295, "XOLAIR": 1.58911939591942, "ZOSTAVAX": 0.1352931946696528, "null": 0.9762432670526164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/885.json
index de8a8e09b27..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/885.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/885.json
@@ -1 +1 @@
-{"null": 1.5337761882450132}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8850.json
index 401de1d3b3b..810ba4fdfba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8850.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8850.json
@@ -1 +1 @@
-{"null": 1.384173841272368}
\ No newline at end of file
+{"null": 0.5500856115978128}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8851.json
index e91f65f4f20..4c490ad03aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8851.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8851.json
@@ -1 +1 @@
-{"APIXABAN": 2.842972186660113, "BRILIQUE": 12.18563227308595, "CLOPIDOGREL": 7.108186267693341, "ELIQUIS": 26.669319047637, "FIRDAPSE": 12.983648366956718, "IBRANCE": 1.14452942497445, "LIXIANA": 12.236597067269292, "PLAVIX": 11.01750496261446, "SUTENT": 2.5952005525565465, "XARELTO": 13.521369733008749, "null": 1.0474769059745617}
\ No newline at end of file
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8852.json
index ca6b1e06619..4f6b49118a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8852.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8852.json
@@ -1 +1 @@
-{"ABATACEPT": 8.122044523976754, "ADALIMUMAB": 10.921638155910475, "AFINITOR": 1.6544094313305089, "AUBAGIO": 1.4435223440339702, "AVASTIN": 7.606822867032728, "BENLYSTA": 2.7632341605416224, "BEVACIZUMAB": 4.881148648130219, "CICLOSPORIN": 1.829393194650494, "CIMZIA": 1.725817717414701, "COSENTYX": 2.3432564418864805, "ELIQUIS": 1.1194009578903623, "EXJADE": 2.223586435813285, "FIRDAPSE": 7.93707873892532, "HIZENTRA": 3.2654064625317405, "HUMALOG": 3.0540353567091656, "IBRANCE": 2.320430899703708, "IBUPROFEN": 1.808472243104484, "ILARIS": 220.4631259569844, "INSULIN": 1.892679514787859, "LANTUS": 1.4240116669993397, "MEPOLIZUMAB": 6.128456544084177, "MYCOPHENOLATE": 7.200708827071009, "NEXOBRID": 560.1063922133287, "RITUXIMAB": 2.018068702556373, "ROACTEMRA": 4.691349370859911, "SIMPONI": 2.473830686870849, "SOMAVERT": 82.84083206435105, "STELARA": 1.2683871106628262, "SUTENT": 2.8504652179302346, "XELJANZ": 6.106069231784663}
\ No newline at end of file
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8853.json
index d0cf131f947..f8f59fb7255 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8853.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8853.json
@@ -1 +1 @@
-{"CUBICIN": 30.984574869612715, "KEPPRA": 7.835741715524683}
\ No newline at end of file
+{"ALEMTUZUMAB": 15.929766477549755, "ASPARAGINASE": 231.63485125133508, "CICLOSPORIN": 13.063337366536397, "CYTARABINE": 73.19461253797118, "SPINRAZA": 51.23897082039803, "SYNAGIS": 40.67945089811968, "null": 0.2909769675893282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8854.json
index 8edfb665180..aee2031a335 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8854.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8854.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 2.2757034980706203, "COSENTYX": 5.913793630213956, "ELIQUIS": 1.2419460305570722, "ERTAPENEM": 213.8818134471567, "HUMIRA": 4.921689536004323, "SUTENT": 1.4373513089902863, "XELJANZ": 4.196760124655299, "null": 1.7203774532881728}
\ No newline at end of file
+{"null": 1.9551908580502773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8855.json
index 25bcff04d30..c5edef39ed7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8855.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8855.json
@@ -1 +1 @@
-{"null": 1.1733358945517447}
\ No newline at end of file
+{"ARIPIPRAZOLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8856.json
index 65c67d98bf1..cc3f20ddf8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8856.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8856.json
@@ -1 +1 @@
-{"null": 1.099422406890062}
\ No newline at end of file
+{"AIMOVIG": 0.3589211954911956, "ARAVA": 0.0875811851959552, "AUBAGIO": 1.5844278077374, "AVANDIA": 1.3668739370251115, "BETAFERON": 2.8328005403394143, "BEXSERO": 3.57438712723642, "BIKTARVY": 1.796846728049546, "BRIDION": 5.2147743473316295, "BUPIVACAINE": 6.695078980430599, "BUPRENORPHINE": 0.7187084314993406, "CELLCEPT": 0.4379342771874902, "CHAMPIX": 0.5452826617918946, "CICLOSPORIN": 0.249502774609161, "CIMZIA": 0.3192751658960294, "CLOPIDOGREL": 0.4510920633557247, "COMIRNATY": 0.9354455578909816, "COSENTYX": 0.4221946700509618, "CYMBALTA": 0.3738415541524008, "CYTARABINE": 0.5436812719179026, "DULOXETINE": 1.025093303469609, "ELIQUIS": 0.8766272721923329, "ENTRESTO": 0.3077833362017608, "EXFORGE": 0.6144838740833839, "EYLEA": 0.6689141288890301, "FASLODEX": 0.854551283879262, "FENTANYL": 2.9771327430042733, "FORSTEO": 0.8350664290988628, "GARDASIL": 6.948879687817077, "HIZENTRA": 1.1796992204101924, "HUMALOG": 1.4951257483360183, "IBRANCE": 0.6160989002632352, "INSULIN": 0.502526916236783, "ISENTRESS": 2.2432610287349166, "JANUMET": 1.0237213970172885, "JARDIANCE": 0.2598982353444274, "KEPPRA": 0.8372879564982504, "KESIMPTA": 2.623151903764049, "KEYTRUDA": 0.5127476064193681, "LANTUS": 1.784383991087663, "LATUDA": 0.9967341097280086, "LEVOFLOXACIN": 1.011567169728598, "LYRICA": 1.7411832720244147, "MIDAZOLAM": 0.919074957916286, "MODERNA": 0.3275814721188522, "NEXAVAR": 0.2892323653743351, "OCRELIZUMAB": 0.90998960260362, "OLANZAPINE": 0.3371864529524394, "OPDIVO": 0.6125565570360074, "PEGASYS": 0.2842344650354768, "PLAVIX": 1.2261549375112788, "SHINGRIX": 2.8853121020806904, "SIMPONI": 0.370940770430637, "SOLIRIS": 0.613101494869076, "SPIKEVAX": 0.8779414605361902, "STALEVO": 4.33061368972657, "STELARA": 0.7189218755648329, "SUTENT": 0.7573621905164226, "TAMIFLU": 0.8072164394675476, "TASIGNA": 0.781635697951992, "TOVIAZ": 1.3260594252136582, "TOZINAMERAN": 2.5985894705663344, "TRUVADA": 0.1767756983036007, "TWINRIX": 4.298732589113557, "VAXZEVRIA": 0.9430374640671022, "VIAGRA": 2.0464886766952586, "XELJANZ": 0.9070637001813108, "XOLAIR": 0.4135267761842635, "XTANDI": 0.6455383664675151, "ZOSTAVAX": 0.8095354697680502, "ZYPREXA": 0.583690758368823, "null": 1.2192189401917533}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8857.json
index 10398da5021..b3a19076277 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8857.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8857.json
@@ -1 +1 @@
-{"ABATACEPT": 15.495063966225494, "ARAVA": 7.603789562738561, "ENBREL": 97.71318189320714, "HUMIRA": 21.21109314334856}
\ No newline at end of file
+{"COMIRNATY": 0.4456828761975359, "null": 0.9328036487330232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8858.json
index 0b580fa08e4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8858.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8858.json
@@ -1 +1 @@
-{"AIMOVIG": 1.541818765047383, "ATRIPLA": 25.625364501547597, "BENRALIZUMAB": 79.50525212969944, "EVENITY": 11.054667842951089, "EVISTA": 8.692064607518123, "EXFORGE": 2.537606806803676, "FIRDAPSE": 3.720009960551506, "FORSTEO": 11.449877682352518, "HUMALOG": 1.6125067872971488, "HUMIRA": 1.0425961296731423, "IBRANCE": 1.9233289949642531, "LANTUS": 2.320505649155228, "LYRICA": 1.184566869901044, "METHOTREXATE": 1.0001784665535929, "OMALIZUMAB": 1.0180532875917585, "REVATIO": 2.984178247355816, "RIVASTIGMINE": 133.4719166609001, "SIMPONI": 1.4719354441652297, "STRIBILD": 12.41062327368115, "SUBOXONE": 2.8038879955139118, "TOVIAZ": 2.138625514083853, "TRELEGY": 1.2872902878491623, "TRUVADA": 13.115803347275715, "VIAGRA": 1.0594863471568052, "VIREAD": 8.21730543076955, "XELJANZ": 3.844355607509263, "XOLAIR": 1.2565231078146444, "ZOSTAVAX": 1.1736401530334108}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8859.json
index 61a8327a177..6419f2c5fc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8859.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8859.json
@@ -1 +1 @@
-{"ARAVA": 7.659929583161888, "SIMPONI": 13.54534382099552, "null": 1.1023651719999816}
\ No newline at end of file
+{"null": 1.6444875234032843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/886.json
index 713fda481c5..7c0a93f1006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/886.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/886.json
@@ -1 +1 @@
-{"IBUPROFEN": 61.6138247137884, "null": 1.388842788657508}
\ No newline at end of file
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8860.json
index 4314ffa2c64..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8860.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8860.json
@@ -1 +1 @@
-{"null": 1.016791246989776}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8861.json
index 1d782d8c3f1..884d40a9b85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8861.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8861.json
@@ -1 +1 @@
-{"LANTUS": 21.310252250294347, "null": 1.3487236733088688}
\ No newline at end of file
+{"AIMOVIG": 568.1813127865374, "BOTULINUM": 217.42587868079025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8862.json
index b2efebd1e31..4eca3c9b70c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8862.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8862.json
@@ -1 +1 @@
-{"null": 4.826380696809855}
\ No newline at end of file
+{"CELLCEPT": 275.258555896735}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8863.json
index 738281c8d97..86d69c6c8cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8863.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8863.json
@@ -1 +1 @@
-{"null": 1.756196526127696}
\ No newline at end of file
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8864.json
index f58fe62df35..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8864.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8864.json
@@ -1 +1 @@
-{"ELIQUIS": 2.002012907756609, "HUMALOG": 1.889730271963923, "KEPPRA": 6.753798690662763, "LANTUS": 1.2423837318597992, "OPSUMIT": 5.009474933133349, "STELARA": 3.5124705460272687, "XELJANZ": 2.282167278670006, "null": 3.1468294319621517}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8865.json
index 65d74a8b21a..defc44de3e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8865.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8865.json
@@ -1 +1 @@
-{"null": 4.908255043006962}
\ No newline at end of file
+{"AVAMYS": 18.222288147309275, "COMIRNATY": 1.2371746535561845, "IBRANCE": 1.7829003524819105, "NUCALA": 14.613319935169656, "OPSUMIT": 3.701599675217654, "SPIKEVAX": 0.7130643855222835, "TOZINAMERAN": 3.2627994880564866, "VAXZEVRIA": 1.500762954272126, "XOLAIR": 2.3568381766486555, "ZOSTAVAX": 2.908964427376648, "null": 0.4651454322983055}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8866.json
index 8dce4a16fee..0d8a63285ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8866.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8866.json
@@ -1 +1 @@
-{"BRINTELLIX": 27.577075817966666, "DULOXETINE": 37.16188634865584, "KEPPRA": 15.54106441075508, "OLANZAPINE": 17.458444581781713, "null": 1.250735901542731}
\ No newline at end of file
+{"COMIRNATY": 0.1974864031867363, "IBRANCE": 5.719704035218321, "OPSUMIT": 8.322349197140197, "null": 1.0500269659353247}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8867.json
index eb9937eca89..ae0987c2b9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8867.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8867.json
@@ -1 +1 @@
-{"ABILIFY": 1.9844681546446776, "APROVEL": 10.505764592652532, "CYMBALTA": 2.037818023336037, "DAPTOMYCIN": 134.8817577338964, "ELIQUIS": 3.717334093272944, "FYCOMPA": 17.40906569057788, "HUMALOG": 7.187099223907235, "IRBESARTAN": 25.572174983357847, "KEPPRA": 6.924782833735076, "LACOSAMIDE": 17.463635005115616, "LEVETIRACETAM": 2.218197256067405, "LYRICA": 4.618120617291731, "MIDAZOLAM": 7.322811070309023, "OLANZAPINE": 11.013083263651046, "PREGABALIN": 10.027893139317698, "RISPERIDONE": 19.8768074989713, "SITAGLIPTIN": 94.19399297381086, "ZYPREXA": 2.4635423448112053, "null": 2.5538815374624657}
\ No newline at end of file
+{"null": 1.6587268853734356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8868.json
index 8507a1628c8..571d3310ba6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8868.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8868.json
@@ -1 +1 @@
-{"ABASAGLAR": 12.477415229121013, "ACTRAPID": 16.329528189158147, "APIDRA": 72.10811377078747, "APROVEL": 2.118431224478702, "BRIDION": 2.595517953807057, "CHLORHEXIDINE": 10.970524853087676, "DAPTOMYCIN": 30.46158083737492, "DESLORATADINE": 5.331284447257246, "EXFORGE": 1.338208796307644, "FENTANYL": 2.193926868898389, "FIASP": 48.52442661959076, "GARDASIL": 1.9510710413818664, "HUMALOG": 26.60076480993916, "INSULATARD": 21.98845063315312, "INSULIN": 13.548708694450076, "IRBESARTAN": 2.127178100957832, "JANUMET": 1.6371053755157854, "KEPPRA": 2.177022848707355, "LANTUS": 7.689404909033826, "LEVEMIR": 19.17303623246681, "MEPOLIZUMAB": 1.8519829916843888, "MIDAZOLAM": 1.8351578112331304, "NOVOMIX": 83.92931315587076, "NOVORAPID": 12.17244398819975, "PANTOPRAZOLE": 1.2337915902146432, "PROQUAD": 42.33311135124024, "TWINRIX": 3.039309237229864, "null": 1.7791096118153316}
\ No newline at end of file
+{"COMIRNATY": 1.877246585213468, "LEVOFLOXACIN": 20.41130703621289, "SPIKEVAX": 1.2284877798635214, "VAXZEVRIA": 0.7089325260442508, "null": 0.2242840304775557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8869.json
index 145c3eece1a..3a9d0cf08cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8869.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8869.json
@@ -1 +1 @@
-{"null": 10.099760554073583}
\ No newline at end of file
+{"null": 2.118328606160788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/887.json
index 522ee8d28b7..bec0750bb82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/887.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/887.json
@@ -1 +1 @@
-{"BYETTA": 136.7899781858648}
\ No newline at end of file
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8870.json
index b72ad642b7e..5a45fa881a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8870.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8870.json
@@ -1 +1 @@
-{"null": 2.596795586362377}
\ No newline at end of file
+{"HIZENTRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8871.json
index aa7cfe22f39..2613ac8084e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8871.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8871.json
@@ -1 +1 @@
-{"null": 4.836185055698578}
\ No newline at end of file
+{"ASPARAGINASE": 203.17410242714985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8872.json
index 90b30d1cac6..ab9942bdc32 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8872.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8872.json
@@ -1 +1 @@
-{"AIMOVIG": 3.506081451669452, "ANORO": 21.615788087378544, "APIDRA": 7.34919612818718, "BENLYSTA": 13.667536751165205, "BYDUREON": 52.990063599492, "BYETTA": 3.4736591190419754, "COSENTYX": 2.870427212535945, "FASENRA": 14.498826930334516, "FIASP": 9.875135843276365, "INCRUSE": 24.373815622404315, "INSULIN": 1.7732869347594198, "LANTUS": 12.03079139240895, "MOVYMIA": 169.257777761374, "NEULASTA": 5.898162686277333, "NOVORAPID": 5.895279498626724, "NUCALA": 7.756983701620193, "RELVAR": 14.343819251116912, "TERROSA": 44.20027338226655, "TOUJEO": 23.08276218074281, "TRELEGY": 69.05598797501257, "null": 2.617717026796781}
\ No newline at end of file
+{"YESCARTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8873.json
index ba8b46cc3dc..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8873.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8873.json
@@ -1 +1 @@
-{"ABASAGLAR": 2.684229180269249, "ABILIFY": 3.3895779553668515, "ACTRAPID": 3.2197153790718134, "ADENURIC": 5.087540655383932, "AERIUS": 1.2846445148535917, "AIMOVIG": 7.93347978391759, "APIDRA": 2.1722458020917, "APROVEL": 2.2827999164503976, "BARACLUDE": 1.125507269637487, "BENRALIZUMAB": 2.423575731257198, "BETAFERON": 1.2710883631730772, "BETMIGA": 5.946208146776063, "BIKTARVY": 4.014739647276096, "BONVIVA": 1.487959365193635, "BRINTELLIX": 5.63108858441618, "BRIVIACT": 2.4779219780893005, "BUPRENORPHINE": 2.941218171317923, "BYDUREON": 4.06103647505537, "CABOTEGRAVIR": 5.292154298730349, "CARBIDOPA": 3.846212459437659, "CIRCADIN": 4.568922209900865, "COAPROVEL": 3.186597936991189, "COMTAN": 13.49851266687642, "COPALIA": 24.675147702071957, "CYMBALTA": 1.0521504531251602, "DAFIRO": 13.0030641247141, "DAPAGLIFLOZIN": 2.320587206263502, "DESCOVY": 2.527997699987852, "DESLORATADINE": 1.410566794905869, "DIFICLIR": 8.015360503660864, "EFIENT": 1.764958590941585, "ELIQUIS": 2.305527318333674, "EMEND": 1.611517052174581, "EMTRICITABINE": 1.3269830234922635, "ENTACAPONE": 2.7074472992354206, "ENTRESTO": 13.034081218463443, "EPCLUSA": 1.4319644550522856, "EUCREAS": 1.5037396330153143, "EVRA": 11.930155209492296, "EXELON": 3.25153303923832, "EXFORGE": 11.309267465121987, "EYLEA": 6.9293358692259455, "FEBUXOSTAT": 2.6376589170415925, "FENTANYL": 2.1604952900412937, "FIASP": 6.770485719468444, "FLUTICASONE": 1.3730157533834797, "FYCOMPA": 1.3183833836428067, "GALAFOLD": 2.434036577458104, "GALVUS": 1.5290801861994696, "GENVOYA": 2.0275586377277617, "GLUCAGON": 3.338051756732825, "HUMALOG": 3.7549919374923535, "INCRUSE": 1.2843647253084696, "INSULIN": 4.567874105726318, "ISENTRESS": 3.390004166111179, "JAKAVI": 1.7228026879640883, "JANUMET": 6.167337163403306, "JANUVIA": 4.329146970490279, "KEPPRA": 2.191300379341916, "LANTUS": 3.0799391981728483, "LATUDA": 4.8387584713696965, "LEVEMIR": 2.536656019225945, "LIXIANA": 4.600057914450002, "LYUMJEV": 9.733286507377985, "MEKINIST": 1.0375745492538606, "MELATONIN": 1.5357258472159796, "MIMPARA": 6.851611353012378, "MIXTARD": 4.966540947246091, "MULTAQ": 2.202025732545953, "NEULASTA": 14.208127611540537, "NEVANAC": 7.9308903828756705, "NOVORAPID": 13.286197041593647, "NOXAFIL": 1.3048635571282443, "OMALIZUMAB": 1.54291437386764, "OMNITROPE": 9.245741986126196, "OXYBUTYNIN": 1.2963524802638815, "PROPRANOLOL": 1.4183663806336793, "QUTENZA": 9.423568048248354, "RANEXA": 3.366464162472266, "RANOLAZINE": 3.714944082924613, "RASILEZ": 4.4064031125581655, "RELVAR": 3.6732576530044745, "RYBELSUS": 1.5109189654814696, "SAXENDA": 3.17691861269496, "SEMAGLUTIDE": 4.325201595762777, "SILDENAFIL": 1.096339553115478, "SOVALDI": 1.0924225636758618, "SPIRONOLACTONE": 1.0332133207530574, "STALEVO": 16.15472535526383, "SUBOXONE": 8.221412740242723, "SUFENTANIL": 1.0210421187536052, "TELMISARTAN": 1.0556891562254145, "TEMODAL": 1.6513535534791888, "TOUJEO": 1.832266074854998, "TOVIAZ": 2.1179398221122367, "TRELEGY": 2.314015666238832, "TREMFYA": 1.340078152293568, "TRESIBA": 2.402019488954961, "VALSARTAN": 11.534293420904335, "VELMETIA": 3.9069895667692784, "VENETOCLAX": 1.329715218514025, "VIMPAT": 2.2456317062, "XTANDI": 2.234417457183803, "XYREM": 2.882598558017876, "null": 2.3016747022859603}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8874.json
index af625d7ac14..fd0151db097 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8874.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8874.json
@@ -1 +1 @@
-{"CANAKINUMAB": 39948.25834000792}
\ No newline at end of file
+{"PEMBROLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8875.json
index 88cbf4a7fda..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8875.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8875.json
@@ -1 +1 @@
-{"SPIKEVAX": 21.33904342330189}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8876.json
index 0f155f78e11..416b984744d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8876.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8876.json
@@ -1 +1 @@
-{"ABATACEPT": 10.694081544966172, "ADALIMUMAB": 9.016508119717496, "ARAVA": 6.262361852890722, "CIMZIA": 20.774200872363217, "ENBREL": 8.230361510376955, "FENTANYL": 5.793442365188687}
\ No newline at end of file
+{"NEXAVAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8877.json
index 6da6e667bec..1079b51874c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8877.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8877.json
@@ -1 +1 @@
-{"null": 1.9305522787239413}
\ No newline at end of file
+{"YONDELIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8878.json
index ad4d5117ea1..2754d939e5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8878.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8878.json
@@ -1 +1 @@
-{"null": 1.9407976366233173}
\ No newline at end of file
+{"BEVACIZUMAB": 32.86472101006021, "KEYTRUDA": 12.31315374124585, "null": 0.3227230149301101}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8879.json
index 7f2675e6c95..439c968904e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8879.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8879.json
@@ -1 +1 @@
-{"OLANZAPINE": 34.39158731469135, "null": 1.951361765036119}
\ No newline at end of file
+{"DOCETAXEL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/888.json
index 0872dcfa505..b2b3a423453 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/888.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/888.json
@@ -1 +1 @@
-{"BYETTA": 37.41705141092123, "JANUVIA": 9.089296311098654, "null": 1.10834270343902}
\ No newline at end of file
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8880.json
index 016e2c0b0fd..1eda5f28172 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8880.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8880.json
@@ -1 +1 @@
-{"VFEND": 271.5953308578652, "VORICONAZOLE": 62.95058771245306, "null": 1.0262731573402404}
\ No newline at end of file
+{"ABILIFY": 3.605108055435795, "AERIUS": 4.251224173395248, "ANTIBIOTICS": 26.71934929252364, "ARIPIPRAZOLE": 8.103336412672641, "ATAZANAVIR": 99.44991154707223, "ATRIPLA": 0.4138419269772351, "BIKTARVY": 2.364334584402473, "BORTEZOMIB": 7.083730416430863, "BRINTELLIX": 1.0457744505600814, "BRIVIACT": 5.753530859635969, "BUPRENORPHINE": 2.949829083741751, "CHAMPIX": 25.11822714408249, "CIMZIA": 0.2731066997712068, "COMIRNATY": 0.027196574403577, "COMTAN": 7.937459235975657, "COSENTYX": 0.8335510273774371, "CYMBALTA": 3.9601248898739394, "DEXAMETHASONE": 0.8342068224116054, "DOXORUBICIN": 1.9563828183862295, "ENFUVIRTIDE": 49.72140767682633, "ENTRESTO": 0.4685102580685386, "FYCOMPA": 5.685450323534483, "HARVONI": 2.074809780275474, "INTRONA": 3.3343337518119984, "KEPPRA": 4.225795447751447, "LATUDA": 13.471220864343618, "LEVETIRACETAM": 3.360779403643656, "LEVODOPA": 12.369932604489309, "LEVOFLOXACIN": 1.0903554301880898, "LYRICA": 0.8823017753988942, "OLANZAPINE": 5.36308847427398, "PEGASYS": 3.679762711832305, "PEGINTRON": 4.397214970717138, "RIBAVIRIN": 2.147162603587857, "RISPERIDONE": 9.838709216430772, "SIFROL": 4.578169682881997, "SPIKEVAX": 0.0763430843618313, "STALEVO": 5.749322435225319, "SUBOXONE": 7.139590069125695, "TAMIFLU": 2.5087993514651235, "TOZINAMERAN": 0.262005648957619, "VARENICLINE": 11.530650983975736, "VAXZEVRIA": 0.0679976880829577, "VIMPAT": 2.999011153345502, "XYREM": 9.683113198735764, "ZYPREXA": 4.850032534517471, "null": 1.90661115812611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8881.json
index 90fd89fbdd0..d6835e2abf5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8881.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8881.json
@@ -1 +1 @@
-{"null": 1.4255772410150558}
\ No newline at end of file
+{"null": 1.567127714907509}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8882.json
index b99bbb3c47e..b755b70da02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8882.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8882.json
@@ -1 +1 @@
-{"IRBESARTAN": 27.237514801319797, "NEXAVAR": 6.102032463806109, "OPTIMARK": 27.82084979076061, "VECTIBIX": 82.14570575782956}
\ No newline at end of file
+{"AUBAGIO": 4.25204866183232, "BENZODIAZEPINES": 122.0268062117308, "BETAFERON": 13.538559077179602, "CICLOSPORIN": 2.0601321830737027, "COMIRNATY": 0.6984416864769231, "FAMPYRA": 8.253403357362089, "GARDASIL": 60.87283161650386, "LEMTRADA": 11.09274194969022, "SPIKEVAX": 0.3116011874786461, "SUFENTANIL": 15.96645380539012, "VAXZEVRIA": 0.4808192355056792, "null": 0.7521358421273756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8883.json
index d9a581945ae..49291d56f60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8883.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8883.json
@@ -1 +1 @@
-{"BUPRENORPHINE": 9.91141519496481, "BUVIDAL": 74.95806986209539, "COVID19": 1.2433535685660235, "CYMBALTA": 4.72685073686399, "SUBOXONE": 9.518967689817346, "null": 1.9783012608465709}
\ No newline at end of file
+{"LEVODOPA": 980.963496440671, "null": 1.1246258934910878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8884.json
index df4caf5490b..dcb1015c96b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8884.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8884.json
@@ -1 +1 @@
-{"null": 3.444647014378324}
\ No newline at end of file
+{"JARDIANCE": 104.4792793098068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8885.json
index 941910b3f3b..53631faabb4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8885.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8885.json
@@ -1 +1 @@
-{"null": 28.122271498465786}
\ No newline at end of file
+{"BUPIVACAINE": 25.21998376830586, "CLOPIDOGREL": 5.9483991309024695, "COMIRNATY": 0.335381293279629, "CYTARABINE": 3.64482324948938, "DEXAMETHASONE": 2.552271743327916, "EFAVIRENZ": 10.0263513272291, "ELIQUIS": 2.449858961391605, "ENOXAPARIN": 6.77966518748818, "FENTANYL": 6.701255675026886, "GARDASIL": 2.8724471925193984, "LANTUS": 0.7998543934438667, "LEVETIRACETAM": 6.776141061300896, "PEGINTRON": 1.2803814549962538, "PLAVIX": 1.1239248609537995, "SPIKEVAX": 0.208920332301527, "SUTENT": 1.268511263742378, "TOZINAMERAN": 0.3198980044124699, "VAXZEVRIA": 0.2981605322302343, "VIAGRA": 4.369812844927618, "null": 1.5872183087657097}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8886.json
index 1673ad2e012..3bd8adf093a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8886.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8886.json
@@ -1 +1 @@
-{"null": 8.67536490504203}
\ No newline at end of file
+{"null": 0.6251346487365609}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8887.json
index ed2b8d70a4a..3110fa1e68a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8887.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8887.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 1.686217852674232, "EXVIERA": 23.521585810174944, "NEXAVAR": 2.7508372151864373, "OCALIVA": 10.414216359918186, "REYATAZ": 9.993287100285988, "SAXENDA": 2.0406543872942104, "STIVARGA": 3.511508633704869, "SUTENT": 81.64724897614563, "VOTRIENT": 3.808115026102385}
\ No newline at end of file
+{"COMIRNATY": 1.3618038439543516, "SPIKEVAX": 0.6594720948451166, "null": 0.6408781558040823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8888.json
index ca0fe0afaba..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8888.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8888.json
@@ -1 +1 @@
-{"JARDIANCE": 93.02030402710128}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8889.json
index fdffa6dd24c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8889.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8889.json
@@ -1 +1 @@
-{"null": 1.7203581838430817}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/889.json
index f8731e168bd..5fce5ca9691 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/889.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/889.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.3392656105732696, "BYETTA": 38.51974539525071, "JANUMET": 31.078639217729645, "JANUVIA": 45.911639727923706}
\ No newline at end of file
+{"null": 0.7274847347364433}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8890.json
new file mode 100644
index 00000000000..2779de6d4c6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8890.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 31.743506464049855, "XYREM": 102.17006879388096, "null": 1.7411560367139534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8891.json
new file mode 100644
index 00000000000..ead8725c17e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8891.json
@@ -0,0 +1 @@
+{"null": 0.6805743670107615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8892.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8892.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8893.json
new file mode 100644
index 00000000000..3391b503f16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8893.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 11.7300276302105, "MIMPARA": 147.73537481203763, "null": 1.2609913103883923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8894.json
new file mode 100644
index 00000000000..e09fbbd49e2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8894.json
@@ -0,0 +1 @@
+{"null": 2.0421948676014465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8895.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8895.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8896.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8896.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8897.json
new file mode 100644
index 00000000000..fa7ba6c05bd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8897.json
@@ -0,0 +1 @@
+{"null": 1.447124326856896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8898.json
new file mode 100644
index 00000000000..c0bd227b1a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8898.json
@@ -0,0 +1 @@
+{"MIMPARA": 487.32319843541393, "null": 1.9747982482071536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8899.json
new file mode 100644
index 00000000000..22bb5490837
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8899.json
@@ -0,0 +1 @@
+{"MIMPARA": 819.8834597316322, "null": 0.7775215640317513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/89.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/89.json
index 6a2769cf96d..9cdee667a8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/89.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/89.json
@@ -1 +1 @@
-{"AMINOSALICYLIC": 1.5629875450751076, "BUPRENORPHINE": 1.4789566383826722, "CANCIDAS": 5.918102830647242, "CELLCEPT": 1.5563364922626923, "CICLOSPORIN": 1.119173967239729, "COAPROVEL": 4.435461632008114, "CRIXIVAN": 13.537338732351133, "DULOXETINE": 2.798329747765377, "EMPAGLIFLOZIN": 7.003727962019444, "EXJADE": 2.1980557711728936, "FENTANYL": 1.5981283703466789, "FORXIGA": 5.369864855215974, "IBUPROFEN": 7.098283005252054, "IRBESARTAN": 3.19258373693702, "JANUMET": 1.526249532042831, "JANUVIA": 1.6227120585115722, "JARDIANCE": 11.579596267138612, "KEPPRA": 1.3428070841268942, "LACOSAMIDE": 3.792393558189127, "LAMIVUDINE": 4.607419543616195, "MICARDIS": 1.9258047095163464, "MIDAZOLAM": 3.491393240837627, "NOVONORM": 8.83169939629433, "NOVORAPID": 1.8677590319451716, "OLANZAPINE": 1.1642462243192109, "ROTATEQ": 3.917466984994348, "ZYPREXA": 2.216967025830745, "null": 2.8382245636667927}
\ No newline at end of file
+{"null": 0.5026955502585587}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/890.json
index dc791229995..ae76925bfb3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/890.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/890.json
@@ -1 +1 @@
-{"BYETTA": 213.21945798769596, "JANUMET": 121.48265306869853, "JANUVIA": 207.5945946224801}
\ No newline at end of file
+{"ANAKINRA": 691.0562639530008, "ENBREL": 6.293770880227515, "I": 3002.8779500427586, "null": 0.8546525567166948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8900.json
new file mode 100644
index 00000000000..9590997b68f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8900.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 5.252170055826456, "MIMPARA": 988.230776727609, "null": 0.8232476804709978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8901.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8901.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8902.json
new file mode 100644
index 00000000000..e335da7389f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8902.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7403446483300402, "null": 0.3371386286315536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8903.json
new file mode 100644
index 00000000000..0e472734f68
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8903.json
@@ -0,0 +1 @@
+{"BYDUREON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8904.json
new file mode 100644
index 00000000000..e2c2dd3ab35
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8904.json
@@ -0,0 +1 @@
+{"null": 7.505399154951763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8905.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8905.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8906.json
new file mode 100644
index 00000000000..556f0a9add2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8906.json
@@ -0,0 +1 @@
+{"null": 1.0172532373180796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8907.json
new file mode 100644
index 00000000000..38918ba0f57
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8907.json
@@ -0,0 +1 @@
+{"CASPOFUNGIN": 407.845926029848, "null": 5.200125637848461}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8908.json
new file mode 100644
index 00000000000..17573947d77
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8908.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 3.6346993772259433, "CICLOSPORIN": 0.9415345711982884, "COMIRNATY": 1.9144754678058429, "ELIQUIS": 0.4285880690640242, "FENTANYL": 1.1271183315688893, "GARDASIL": 4.392160465170734, "METHOTREXATE": 1.488522295083608, "PEGASYS": 0.4727770766461385, "PEGINTRON": 1.0027692452752617, "PLAVIX": 0.9851710807668824, "SHINGRIX": 2.0905408548852527, "SPIKEVAX": 0.643144051392471, "TOZINAMERAN": 0.1842731756902125, "TWINRIX": 9.11074287435665, "VAXZEVRIA": 0.9639047708403168, "null": 1.1740141367737431}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8909.json
new file mode 100644
index 00000000000..3360b0dcc59
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8909.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9862355273620576, "null": 0.6180072909783187}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/891.json
index fe1072f126b..b3754436671 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/891.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/891.json
@@ -1 +1 @@
-{"BYETTA": 6.564460759168819, "CICLOSPORIN": 2.1814425739561663, "ESOMEPRAZOLE": 14.208921112027156, "JANUMET": 7.967569967013531, "JANUVIA": 10.065711819156355, "NEXAVAR": 3.1322955378131527, "SAXENDA": 15.290520358307775, "SUTENT": 1.1931818143641102, "XELJANZ": 1.867745060253007}
\ No newline at end of file
+{"null": 0.9167239559827142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8910.json
new file mode 100644
index 00000000000..778f4aad1f0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8910.json
@@ -0,0 +1 @@
+{"XELJANZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8911.json
new file mode 100644
index 00000000000..4f7cb8d6fae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8911.json
@@ -0,0 +1 @@
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8912.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8912.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8913.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8913.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8914.json
new file mode 100644
index 00000000000..ad2d367d958
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8914.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.605071039840537, "AIMOVIG": 0.5869032258911582, "APIDRA": 1.0248916307082725, "ARANESP": 0.7685729164383243, "ARIPIPRAZOLE": 1.084480835122718, "AZILECT": 33.47523438910083, "BYDUREON": 2.2463072447558505, "CARBIDOPA": 102.70129643963033, "CEREZYME": 365.8581108859343, "COMIRNATY": 0.1700589009332838, "COMTAN": 141.7651698625537, "CYMBALTA": 1.1054970337511767, "ELIQUIS": 1.9251436886693984, "ENTACAPONE": 89.26674060586625, "EVENITY": 2.926948208048838, "EXFORGE": 1.577990648036634, "FORSTEO": 2.9627899025069766, "HUMALOG": 3.8718907719869913, "IBRANCE": 1.0828881926032443, "JANUMET": 0.832317770323648, "JANUVIA": 1.8818964673302252, "KEPPRA": 0.5771403690611743, "LANTUS": 3.0700704366690013, "LATUDA": 3.670973563437508, "LEVEMIR": 2.080073984659965, "LEVODOPA": 47.02115758391009, "LYRICA": 1.377855530113843, "NEUPRO": 37.36175526731196, "OLANZAPINE": 1.5851607089443165, "PANTOPRAZOLE": 4.845444265310926, "PEGASYS": 0.5205840264622911, "PEGINTRON": 0.9315836311309696, "RANOLAZINE": 8.306014249681576, "SIFROL": 15.664549898185424, "SIMPONI": 1.3861610792087504, "SPIKEVAX": 0.1284560785762347, "STALEVO": 196.40166614224387, "STELARA": 1.4803586154531043, "SUTENT": 0.2901681748135558, "TASIGNA": 1.050261724034598, "TOVIAZ": 11.154932242831832, "TOZINAMERAN": 0.2969112891320349, "TRULICITY": 1.081776314692624, "VAXZEVRIA": 0.0818061606835476, "VIAGRA": 4.699312148714355, "XELJANZ": 2.072278281689352, "XTANDI": 1.5704144656354713, "ZOSTAVAX": 1.064799285929863, "ZYPREXA": 2.54374095667948, "null": 1.5515722317528655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8915.json
new file mode 100644
index 00000000000..64b8e53686a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8915.json
@@ -0,0 +1 @@
+{"CARBIDOPA": 2843.5807093904887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8916.json
new file mode 100644
index 00000000000..1a336f63ece
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8916.json
@@ -0,0 +1 @@
+{"STALEVO": 840.9120212576136, "null": 1.5166603346106122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8917.json
new file mode 100644
index 00000000000..6ec0f307353
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8917.json
@@ -0,0 +1 @@
+{"ENTACAPONE": 195.87889138105592, "LEVODOPA": 161.27818397582072, "OLANZAPINE": 10.394203628700444, "ZYPREXA": 7.115324045415322, "null": 2.2689219175895308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8918.json
new file mode 100644
index 00000000000..1af076b9e9a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8918.json
@@ -0,0 +1 @@
+{"CARBIDOPA": 288.5307595850282, "OLANZAPINE": 19.91247053119856, "null": 0.7680432471092054}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8919.json
new file mode 100644
index 00000000000..4aa9e2189dd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8919.json
@@ -0,0 +1 @@
+{"ABILIFY": 18.55459376855225, "ARIPIPRAZOLE": 19.471873678184963, "ATAZANAVIR": 2.6660025180205214, "AZILECT": 21.3905529021994, "BRINTELLIX": 0.7972205902128936, "CARBIDOPA": 13.154723313172632, "CARIPRAZINE": 88.298763168657, "CICLOSPORIN": 0.8585757208880429, "COMIRNATY": 0.0562560724906985, "COMTAN": 7.084402574685902, "CYMBALTA": 1.113597411292623, "ENTACAPONE": 25.524049144938555, "FORSTEO": 0.4990142603049644, "INVEGA": 21.79121037476481, "JANUMET": 0.8141673873281875, "KEPPRA": 1.453013680164584, "LACOSAMIDE": 2.7560485677460216, "LATUDA": 10.460422764586962, "LEVETIRACETAM": 1.2773221158633852, "LEVODOPA": 38.09030227816618, "LOXAPINE": 34.10754488140372, "LYRICA": 0.9362902121470916, "NEUPRO": 49.79497931617493, "OLANZAPINE": 25.268399196977267, "PEGASYS": 0.3007873998162189, "PEGINTERFERON": 1.9982805262957983, "PEGINTRON": 1.1369744708022111, "PREGABALIN": 4.152837257383991, "PROPRANOLOL": 5.264932741200411, "REAGILA": 25.37826357570688, "RISPERIDONE": 19.074003955242866, "SIFROL": 12.737749659104246, "SPIKEVAX": 0.0373923587647269, "SPIRONOLACTONE": 9.590956800928131, "STALEVO": 7.755478468608146, "SYCREST": 42.65624719921861, "VAXZEVRIA": 0.0361383004327553, "ZYPREXA": 15.681670210029065, "null": 3.2166171233997365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/892.json
index 1c5f4d08e4d..61afe71fd61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/892.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/892.json
@@ -1 +1 @@
-{"null": 1.310505242861575}
\ No newline at end of file
+{"ARAVA": 0.9899518366858716, "BYETTA": 15.156697003631898, "COMBIVIR": 44.60740897940171, "COMIRNATY": 0.1210553576441224, "GARDASIL": 6.2699308076641325, "JANUMET": 19.563454123946705, "JANUVIA": 22.048758276953723, "LANTUS": 1.2241792931695707, "OPSUMIT": 3.613363044113746, "PEGASYS": 2.226816329081166, "ROTATEQ": 42.45810536472584, "SPIKEVAX": 0.2028825808216636, "STELARA": 3.391736716243882, "ZOSTAVAX": 6.517134159264232, "null": 0.7478597553354457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8920.json
new file mode 100644
index 00000000000..1ff03663b1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8920.json
@@ -0,0 +1 @@
+{"CARBIDOPA": 965.97898000275, "null": 0.7011289212253213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8921.json
new file mode 100644
index 00000000000..e9b40f01187
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8921.json
@@ -0,0 +1 @@
+{"AFATINIB": 245.1656015327333, "AFINITOR": 5.099865559109202, "ALEMTUZUMAB": 8.22365875033466, "AVASTIN": 4.349421678818835, "BEVACIZUMAB": 16.41256368494164, "BRAFTOVI": 9.72228291733152, "CETUXIMAB": 34.87132313773825, "COMIRNATY": 0.0781405769713507, "COSENTYX": 1.846843510232822, "CRIXIVAN": 31.694505564086292, "CYTARABINE": 4.426790638793492, "DOCETAXEL": 5.434291712191003, "ERBITUX": 127.35631535512138, "GEFITINIB": 87.68899063871469, "HERCEPTIN": 8.513438932237628, "IRESSA": 110.48531786560513, "IRINOTECAN": 25.954140628263552, "KEYTRUDA": 1.224557231253923, "MEKINIST": 3.384080282196391, "OSIMERTINIB": 101.30965749809664, "PANITUMUMAB": 236.9122316971992, "ROACTEMRA": 4.034067741970288, "STIVARGA": 2.908198723791648, "SUTENT": 0.6746490839365776, "TAGRISSO": 140.35659557675618, "TRAMETINIB": 142.97919276519008, "VECTIBIX": 352.93183242823807, "null": 0.3244354014424812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8922.json
new file mode 100644
index 00000000000..0dd12e349d2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8922.json
@@ -0,0 +1 @@
+{"null": 0.537417779252409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8923.json
new file mode 100644
index 00000000000..31e6891cafc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8923.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 1.6585243724812189, "AVAMYS": 1.1945969853905094, "BRINTELLIX": 1.5904945874993115, "BUDESONIDE": 0.3544845069230952, "CHAMPIX": 1.4514343393532136, "CIMZIA": 0.2839159762716315, "CLOPIDOGREL": 0.5001484493339445, "COMIRNATY": 2.1460733433059844, "CYMBALTA": 0.8420498922573193, "FASLODEX": 0.7417789081011662, "GARDASIL": 1.4143411624587932, "IBRANCE": 0.6239738833962984, "IBUPROFEN": 0.6690956337337224, "JARDIANCE": 0.592038075247116, "KEPPRA": 0.738482054675281, "MEPOLIZUMAB": 0.7183990775631616, "MICARDIS": 1.2376148289660134, "MODERNA": 0.65679645577033, "OCRELIZUMAB": 1.4400895145760657, "PEGASYS": 0.5942092333141238, "PEGINTRON": 1.9458685313101511, "SAXENDA": 1.052110179201088, "SPIKEVAX": 1.317450674999859, "STELARA": 0.4673805832702596, "SUTENT": 0.6240446030351307, "TAMIFLU": 0.8285331894897211, "TOZINAMERAN": 1.6587918788115283, "TRULICITY": 1.5070283248355516, "VAXZEVRIA": 1.448070816224729, "XELJANZ": 0.2412538699220821, "XOLAIR": 0.7096639309816549, "XTANDI": 0.5130419924764373, "null": 0.9363141235893364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8924.json
new file mode 100644
index 00000000000..450b4fd133c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8924.json
@@ -0,0 +1 @@
+{"null": 1.4631329108364377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8925.json
new file mode 100644
index 00000000000..2bb4f312b5f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8925.json
@@ -0,0 +1 @@
+{"ARAVA": 0.4127568184878488, "COMIRNATY": 0.3521702476575917, "KEYTRUDA": 1.4158957663426417, "MMRVAXPRO": 82.10370106574, "SPIKEVAX": 0.1275478664876477, "TOZINAMERAN": 0.275470510342516, "VAXZEVRIA": 0.2105907593270592, "null": 2.450092508608522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8926.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8926.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8927.json
new file mode 100644
index 00000000000..efb551d732b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8927.json
@@ -0,0 +1 @@
+{"AVAMYS": 64.63479428188654, "COMIRNATY": 0.758120254128333, "MMRVAXPRO": 34.78395360307713, "SPIKEVAX": 0.1969951155655391, "TOZINAMERAN": 0.4223603707273443, "VAXZEVRIA": 0.1875628064291808, "null": 1.6927401888282414}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8928.json
new file mode 100644
index 00000000000..9cf90274fa6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8928.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.058327239469239, "null": 0.8441661466746129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8929.json
new file mode 100644
index 00000000000..854a231aaba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8929.json
@@ -0,0 +1 @@
+{"null": 0.855331966490197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/893.json
index 73c7de74c17..7a18b34d5ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/893.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/893.json
@@ -1 +1 @@
-{"DEXAMETHASONE": 3.930677299317784, "FORSTEO": 2.9879697977471733, "LANTUS": 1.1181987067574308, "NEXAVAR": 1.9278218135258407, "OMALIZUMAB": 4.819398578611437, "SAXENDA": 47.086584547086616, "TRULICITY": 4.9969585461101165, "XELJANZ": 1.2875049290238965, "null": 1.1426112718857326}
\ No newline at end of file
+{"ACLIDINIUM": 5.725439129869816, "ARANESP": 170.4040426531827, "ARAVA": 0.1941974203403718, "BENLYSTA": 1.396915284244856, "BUDESONIDE": 0.4937514795406548, "BYDUREON": 1.243143415325105, "CHAMPIX": 0.607183033295814, "CIMZIA": 0.5819312854283609, "COMIRNATY": 0.8181954700780006, "COSENTYX": 0.4180440811477686, "CYMBALTA": 0.2499920104353543, "CYTARABINE": 3.660852485868422, "DARBEPOETIN": 141.54596667567208, "DEXAMETHASONE": 0.5849112473442611, "ELIQUIS": 0.4216175021344187, "ENTYVIO": 4.492587238057249, "EXJADE": 0.7225760140248141, "FLUTICASONE": 33.39337789154102, "GARDASIL": 1.695109486699092, "HUMALOG": 0.5135085654851568, "HUMIRA": 0.7803614500892468, "IBRANCE": 1.0063067687352183, "INSULIN": 2.8521232639984957, "JARDIANCE": 1.1374894029975255, "KEYTRUDA": 0.5852458540851174, "MELATONIN": 7.713953513148684, "NEXAVAR": 0.4443673976935484, "PEGASYS": 1.477737002956917, "PEGINTERFERON": 1.509967931840989, "PEGINTRON": 5.360149010088953, "RINVOQ": 1.8468561031220156, "ROACTEMRA": 3.035335615124995, "SAXENDA": 3.4932959877051197, "SIMPONI": 1.056879642080608, "SOLIRIS": 0.8765281903563945, "SPIKEVAX": 0.6503429077139996, "SPINRAZA": 2.5298747996263806, "STELARA": 1.3447813124282055, "SUBOXONE": 1.1223615049575513, "SUTENT": 0.4568964201340075, "TOZINAMERAN": 1.8622858906511, "TRULICITY": 1.0163986045047744, "VAXZEVRIA": 0.202931221115101, "VICTOZA": 2.313032901340093, "XELJANZ": 1.3936344845629711, "XOLAIR": 0.8052928634115989, "null": 0.3751725670345798}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8930.json
new file mode 100644
index 00000000000..73fb97a6a0d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8930.json
@@ -0,0 +1 @@
+{"EFAVIRENZ": 586.0335193128805, "VAXZEVRIA": 2.7964809680412324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8931.json
new file mode 100644
index 00000000000..644fd9f77f9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8931.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 11.071341322979576, "SOLIRIS": 340.7192574474543, "null": 0.2558157474442306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8932.json
new file mode 100644
index 00000000000..b28cc5c4981
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8932.json
@@ -0,0 +1 @@
+{"null": 1.0697945780850726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8933.json
new file mode 100644
index 00000000000..0ebea32b12d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8933.json
@@ -0,0 +1 @@
+{"null": 2.842174893117785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8934.json
new file mode 100644
index 00000000000..2a8fae8528e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8934.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.7931841872097588, "AMINOSALICYLIC": 1.609770058556152, "ARANESP": 1.5834463481317689, "ARIPIPRAZOLE": 1.2128062021982668, "ASPARAGINASE": 7.125067755412741, "AUBAGIO": 1.2044104533276545, "BRIVARACETAM": 13.619399023248173, "BRIVIACT": 43.44448147852698, "CELLCEPT": 0.8765959079813823, "CICLOSPORIN": 3.138788085727742, "COMIRNATY": 0.2069573834380611, "CYMBALTA": 0.4038386971909153, "DEXAMETHASONE": 4.314623937183979, "FAMPYRA": 3.044180969155387, "FENTANYL": 1.8483359030527835, "FYCOMPA": 23.135567874753814, "GARDASIL": 1.5494722129249474, "IBUPROFEN": 1.358813702246233, "INFANRIX": 8.957637840918013, "KEPPRA": 36.555072943405534, "LACOSAMIDE": 94.6800849143202, "LANTUS": 0.3755230692776983, "LEVETIRACETAM": 46.1992944010548, "LYRICA": 2.060832682739202, "METHOTREXATE": 0.7977158674309128, "MIDAZOLAM": 9.501633303022958, "OLANZAPINE": 0.6092715492638429, "PERAMPANEL": 45.44369259789571, "SPIKEVAX": 0.2118146603645218, "TAMIFLU": 1.3277173634864818, "TOZINAMERAN": 0.4507943684643106, "VAXZEVRIA": 0.2553277342778156, "VIMPAT": 22.32943163219125, "XTANDI": 1.019418768106702, "ZONISAMIDE": 26.277264727374625, "null": 1.0599819084281958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8935.json
new file mode 100644
index 00000000000..5483c27e119
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8935.json
@@ -0,0 +1 @@
+{"BRIVARACETAM": 610.7360466308605, "KEPPRA": 19.220967354975866, "LACOSAMIDE": 70.69648296726015, "LEVETIRACETAM": 37.36526787412522, "VIMPAT": 47.58366789819265, "null": 0.8484118506176109}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8936.json
new file mode 100644
index 00000000000..3e634f46331
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8936.json
@@ -0,0 +1 @@
+{"ATRIPLA": 2.734718924897819, "TRUVADA": 4.124631218771299, "null": 3.987795076283061}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8937.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8937.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8938.json
new file mode 100644
index 00000000000..99d3e1a51fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8938.json
@@ -0,0 +1 @@
+{"ARANESP": 23.23524237815009, "CELLCEPT": 17.301874095436197, "CICLOSPORIN": 23.7408396349701, "MYCOPHENOLATE": 83.11189606042485, "null": 0.383819579268143}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8939.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8939.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/894.json
index d05e16dc5fe..0b604f4aa8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/894.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/894.json
@@ -1 +1 @@
-{"ADALIMUMAB": 1.0300261425378248, "BYETTA": 16.814749060546795, "JANUMET": 22.496983126525677, "JANUVIA": 28.948313782289134}
\ No newline at end of file
+{"COMIRNATY": 0.4262655261515533, "PEGASYS": 1.5136436427368665, "SPIKEVAX": 0.3707819239032666, "SUBOXONE": 4.789006577684701, "TOZINAMERAN": 1.3071268478013018, "VAXZEVRIA": 0.119963323603553, "XELJANZ": 4.250062853263765, "null": 1.0313786680121686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8940.json
new file mode 100644
index 00000000000..0a6a0e42c03
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8940.json
@@ -0,0 +1 @@
+{"CELLCEPT": 68.03731011018417}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8941.json
new file mode 100644
index 00000000000..70efb73552b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8941.json
@@ -0,0 +1 @@
+{"null": 0.8185192226341236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8942.json
new file mode 100644
index 00000000000..adea616a844
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8942.json
@@ -0,0 +1 @@
+{"null": 1.6086976435080844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8943.json
new file mode 100644
index 00000000000..f733f02e757
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8943.json
@@ -0,0 +1 @@
+{"null": 2.6954849018187272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8944.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8944.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8945.json
new file mode 100644
index 00000000000..8511fd4484f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8945.json
@@ -0,0 +1 @@
+{"ATRIPLA": 10.587592173647264, "ELIQUIS": 1.6530151836119862, "EVISTA": 28.37227801280889, "FORSTEO": 13.04652586452305, "HUMALOG": 2.802389600716653, "KALETRA": 12.765270275072217, "STRIBILD": 4.065729447325782, "TRUVADA": 6.244898346236188, "XELJANZ": 4.412031559140672, "null": 1.000614767228647}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8946.json
new file mode 100644
index 00000000000..7275a68121c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8946.json
@@ -0,0 +1 @@
+{"ATRIPLA": 3.122113395383359, "null": 0.8277971119917006}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8947.json
new file mode 100644
index 00000000000..5db21e88c87
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8947.json
@@ -0,0 +1 @@
+{"BRIVARACETAM": 53.23991995776781, "COMBIVIR": 8.213741271929631, "DEXAMETHASONE": 2.694468090862709, "EPIVIR": 9.991896921848657, "ESOMEPRAZOLE": 11.787785913576451, "IBUPROFEN": 7.528151899539772, "KALETRA": 4.9196655553792095, "KEPPRA": 4.98449897180368, "LEVETIRACETAM": 2.964952658625009, "NORVIR": 14.95502870289387, "null": 7.2861357460251375}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8948.json
new file mode 100644
index 00000000000..36ec61c3486
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8948.json
@@ -0,0 +1 @@
+{"null": 4.8229311646374615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8949.json
new file mode 100644
index 00000000000..0d835bfc3f0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8949.json
@@ -0,0 +1 @@
+{"KEPPRA": 26.51506773713168, "null": 0.3968736970429183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/895.json
index a669584f1eb..82e40945a3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/895.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/895.json
@@ -1 +1 @@
-{"BYETTA": 47.36012791478623, "null": 1.8199988886237997}
\ No newline at end of file
+{"ACLIDINIUM": 18.89066446471517, "ARANESP": 2225.452504876328, "BUDESONIDE": 1.6283067600111378, "DARBEPOETIN": 482.6031003037765, "FLUTICASONE": 111.79109350009143, "INSULIN": 5.620461383568686, "MELATONIN": 23.77129496537472, "null": 0.0588157848081115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8950.json
new file mode 100644
index 00000000000..6da67df3647
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8950.json
@@ -0,0 +1 @@
+{"COSENTYX": 21.267464654393425, "SIMPONI": 13.391951093347028, "STELARA": 16.08818896518014, "SUBOXONE": 14.7829858931814, "TASIGNA": 15.183557162608146, "TREMFYA": 58.38511934966896, "null": 0.4591633249217347}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8951.json
new file mode 100644
index 00000000000..d3b4c492cd3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8951.json
@@ -0,0 +1 @@
+{"BARACLUDE": 131.9844283127463, "OLANZAPINE": 10.929856526764167, "PEGASYS": 8.31624681105071, "PEGINTRON": 9.640458377205611, "null": 0.8060530896453263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8952.json
new file mode 100644
index 00000000000..47ca9b6c7c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8952.json
@@ -0,0 +1 @@
+{"ABACAVIR": 30.04171271939711, "ADEFOVIR": 51.170480911540366, "ALEMTUZUMAB": 14.101036063994716, "AMIKACIN": 47.53185946752846, "AMINOSALICYLIC": 3.1236267533958357, "ANIDULAFUNGIN": 41.06116395601374, "ATAZANAVIR": 17.20099959079484, "ATRIPLA": 0.2640282176975749, "AZTREONAM": 55.97792805790844, "BASILIXIMAB": 16.922712759103167, "BIKTARVY": 2.5144235375035864, "BUDESONIDE": 0.9521959084719724, "BUSULFAN": 3.80098741342062, "CABOTEGRAVIR": 183.76987592374437, "CANCIDAS": 11.889853253028583, "CASPOFUNGIN": 42.36796436158664, "CELLCEPT": 1.3552324470708743, "CELSENTRI": 34.94696541122213, "CICLOSPORIN": 2.2767656894683976, "CIDOFOVIR": 29.723942328537767, "COLISTIMETHATE": 60.92862420526939, "COMBIVIR": 2.996309201601516, "CUBICIN": 54.65440177605538, "CYTARABINE": 4.700790345025746, "DAPTOMYCIN": 81.02339386579516, "DARUNAVIR": 100.75133174855743, "DEXAMETHASONE": 1.7866859021315091, "DOLUTEGRAVIR": 83.16547948207413, "EFAVIRENZ": 32.00898742464371, "EMTRICITABINE": 43.67132036894899, "ENTECAVIR": 39.47302722295338, "EPIVIR": 7.643189522437596, "ERTAPENEM": 36.691019677560085, "GANCICLOVIR": 80.30511535194721, "HEPSERA": 7.553551912943149, "HUMIRA": 4.83612561579362, "ISENTRESS": 4.718889058035986, "LAMIVUDINE": 26.15368890218628, "LEVOFLOXACIN": 26.724522486820163, "MICAFUNGIN": 31.156905845030607, "NOXAFIL": 5.083665961297556, "OSELTAMIVIR": 108.42485152512316, "POSACONAZOLE": 56.69041788506062, "REKAMBYS": 96.76241974462664, "RIBAVIRIN": 3.805979651383172, "TAMIFLU": 17.821919168165415, "TIGECYCLINE": 136.24746640883976, "TIVICAY": 11.68661893294461, "TOBRAMYCIN": 45.98290959042277, "VFEND": 1.5065273877741483, "VORICONAZOLE": 20.880268940562104, "null": 0.7551696591930349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8953.json
new file mode 100644
index 00000000000..9d2592bc8d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8953.json
@@ -0,0 +1 @@
+{"RINVOQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8954.json
new file mode 100644
index 00000000000..154d035b117
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8954.json
@@ -0,0 +1 @@
+{"AFINITOR": 2.2239130163867578, "ATRIPLA": 6.539249611821661, "AVANDIA": 1.6330742006760628, "BONVIVA": 29.343236651921647, "DEXAMETHASONE": 4.892951717779329, "ENBREL": 2.1958808983577525, "EVENITY": 48.53169007781396, "FASLODEX": 4.183700382275155, "FENTANYL": 3.1336119980908017, "FORSTEO": 11.0471333534074, "HEPSERA": 49.06039601632977, "IBRANCE": 3.956631021125322, "KEYTRUDA": 2.0493725158764, "METHOTREXATE": 1.997089489519948, "STRIBILD": 5.419408444349534, "SUTENT": 2.895754832619012, "TRUVADA": 4.969325355061479, "VIREAD": 17.89257424991074, "XOFIGO": 42.75146840466586, "XTANDI": 2.305351023381109, "null": 0.5805561306942717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8955.json
new file mode 100644
index 00000000000..c9ada0136cc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8955.json
@@ -0,0 +1 @@
+{"null": 2.51615591671635}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8956.json
new file mode 100644
index 00000000000..f189aa7f2a4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8956.json
@@ -0,0 +1 @@
+{"ABILIFY": 19.16623029155675, "RISPERIDONE": 82.56907334482011, "null": 2.153941142129334}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8957.json
new file mode 100644
index 00000000000..0ea497e1064
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8957.json
@@ -0,0 +1 @@
+{"BENLYSTA": 83.54886481302421, "null": 0.287644386814844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8958.json
new file mode 100644
index 00000000000..345f343827e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8958.json
@@ -0,0 +1 @@
+{"null": 2.588873808515698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8959.json
new file mode 100644
index 00000000000..d66fa1ecf93
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8959.json
@@ -0,0 +1 @@
+{"null": 3.223277659575637}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/896.json
index 226f625992f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/896.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/896.json
@@ -1 +1 @@
-{"AFINITOR": 3.2376706260655514, "BYETTA": 35.72931859108263, "CABOMETYX": 6.74505223900663, "JANUMET": 27.954482521871714, "JANUVIA": 18.785304554755182, "LONSURF": 31.98337498721818, "NEXAVAR": 5.109036920593755, "PEGASYS": 2.3751071361874816, "STIVARGA": 6.794278220510165, "SUTENT": 1.47225813401476, "VOTRIENT": 4.3957767488551465}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8960.json
new file mode 100644
index 00000000000..d96a459188e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8960.json
@@ -0,0 +1 @@
+{"null": 2.144190309909804}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8961.json
new file mode 100644
index 00000000000..0b459841180
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8961.json
@@ -0,0 +1 @@
+{"null": 1.1870177049144868}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8962.json
new file mode 100644
index 00000000000..c665b227245
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8962.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2337987508037002, "NUCALA": 27.071764554749254, "OMALIZUMAB": 10.768058235521456, "VAXZEVRIA": 0.1895897759419536, "XOLAIR": 39.524262476685344, "null": 2.506018921958713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8963.json
new file mode 100644
index 00000000000..5db20dc5145
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8963.json
@@ -0,0 +1 @@
+{"null": 2.846137987720282}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8964.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8964.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8965.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8965.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8966.json
new file mode 100644
index 00000000000..fe982f99abc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8966.json
@@ -0,0 +1 @@
+{"OPTIMARK": 1367.7014714439697, "null": 0.323055015084015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8967.json
new file mode 100644
index 00000000000..037c700e724
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8967.json
@@ -0,0 +1 @@
+{"null": 5.987937106416911}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8968.json
new file mode 100644
index 00000000000..10761cf4642
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8968.json
@@ -0,0 +1 @@
+{"null": 9.984763608579811}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8969.json
new file mode 100644
index 00000000000..334c4bd06a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8969.json
@@ -0,0 +1 @@
+{"null": 0.8340297510290067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/897.json
index 685b992f431..318d1c47a2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/897.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/897.json
@@ -1 +1 @@
-{"JANUVIA": 10.085625649255206, "null": 1.19507782317392}
\ No newline at end of file
+{"null": 5.224948212871338}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8970.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8970.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8971.json
new file mode 100644
index 00000000000..4e4a663abf6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8971.json
@@ -0,0 +1 @@
+{"null": 0.6605473034841044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8972.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8972.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8973.json
new file mode 100644
index 00000000000..dbd5b1d805c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8973.json
@@ -0,0 +1 @@
+{"null": 0.8179166441563179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8974.json
new file mode 100644
index 00000000000..91fc2969713
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8974.json
@@ -0,0 +1 @@
+{"JARDIANCE": 8.886859639932302, "null": 0.7751195723041853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8975.json
new file mode 100644
index 00000000000..d200a60533d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8975.json
@@ -0,0 +1 @@
+{"null": 0.6604911223137445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8976.json
new file mode 100644
index 00000000000..bac674c2fa1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8976.json
@@ -0,0 +1 @@
+{"null": 1.2435810430680123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8977.json
new file mode 100644
index 00000000000..c69ac62fa2d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8977.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.8317956073486599, "VAXZEVRIA": 0.6732608339463086, "null": 0.6917902276977977}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8978.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8978.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8979.json
new file mode 100644
index 00000000000..9d6290e6d36
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8979.json
@@ -0,0 +1 @@
+{"null": 0.6967559409027245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/898.json
index 8dc2e7dae0f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/898.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/898.json
@@ -1 +1 @@
-{"null": 1.3309695082925843}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8980.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8980.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8981.json
new file mode 100644
index 00000000000..06de585354a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8981.json
@@ -0,0 +1 @@
+{"null": 1.4249640033172106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8982.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8982.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8983.json
new file mode 100644
index 00000000000..70b871f6bbc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8983.json
@@ -0,0 +1 @@
+{"CETROTIDE": 654.9371394831838, "GONALF": 615.0420967746273, "ORGALUTRAN": 925.225940880982, "null": 0.3098831732382039}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8984.json
new file mode 100644
index 00000000000..31d81a1ee90
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8984.json
@@ -0,0 +1 @@
+{"ARAVA": 0.2046568478682237, "ATRIPLA": 2.069185070171703, "CICLOSPORIN": 2.3970461581081755, "CYMBALTA": 1.5973861427328244, "ELIQUIS": 2.1404228844778173, "EVENITY": 26.831616776128005, "EVISTA": 48.4583836964676, "EXJADE": 1.635223799669648, "FORSTEO": 25.022099327775365, "HUMALOG": 2.9772735611080363, "IBRANCE": 1.4432979928466756, "JARDIANCE": 1.23151081662647, "LANTUS": 1.0944733479385544, "METHOTREXATE": 1.3856246567790078, "OPSUMIT": 1.6622755843356782, "REVATIO": 5.63731821835583, "SIMPONI": 1.1860984957691547, "SOLIRIS": 1.7516506446486269, "SPIKEVAX": 0.0445528190699383, "STRIBILD": 2.0078561174450296, "SUBOXONE": 1.7268604859211083, "SUTENT": 0.5220386165037164, "TRELEGY": 2.8030863336355973, "TRUVADA": 3.904356311281637, "XELJANZ": 8.052389596289583, "XTANDI": 1.1133931404518458, "null": 1.3198040627521268}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8985.json
new file mode 100644
index 00000000000..a0e593cb87d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8985.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.8999937102515292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8986.json
new file mode 100644
index 00000000000..2dfba8af1c7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8986.json
@@ -0,0 +1 @@
+{"ELIQUIS": 8.438194684813883, "ENOXAPARIN": 83.52936313648688, "PLAVIX": 9.701518926134677, "null": 2.726058341032356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8987.json
new file mode 100644
index 00000000000..b23cd7a0dbf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8987.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3588009141270649, "TOZINAMERAN": 6.099799054429683, "VAXZEVRIA": 2.1127590513905026, "null": 0.6065041885944424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8988.json
new file mode 100644
index 00000000000..e607676af8b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8988.json
@@ -0,0 +1 @@
+{"null": 0.5914967197394623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8989.json
new file mode 100644
index 00000000000..225f163bb2d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8989.json
@@ -0,0 +1 @@
+{"ABACAVIR": 12.334426810172763, "COMIRNATY": 0.518675329618231, "GARDASIL": 7.775901971141212, "JARDIANCE": 8.328358987285599, "null": 1.1805763820274071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/899.json
index 9054213117d..4324003efc3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/899.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/899.json
@@ -1 +1 @@
-{"ASPARAGINASE": 13.61118293712399, "BEDAQUILINE": 15.179544476593026, "CANCIDAS": 14.859991202012823, "CICLOSPORIN": 1.381873831825073, "CLOPIDOGREL": 1.038374529295329, "EXJADE": 8.415419366528496, "EXVIERA": 19.84365712763798, "KAFTRIO": 7.5603166059571665, "KALETRA": 7.594087121217274, "LEVOFLOXACIN": 1.7575606674905226, "NOXAFIL": 20.31168938613883, "PEGINTERFERON": 4.750818852246233, "PEGINTRON": 1.4837169402329775, "SOLIRIS": 3.088625228958405, "STIVARGA": 7.916564433898229, "TASIGNA": 3.171598895672937, "TRACLEER": 12.174626518170689, "VFEND": 7.218602277848142, "ZYPREXA": 1.2833119492748803, "null": 1.690999373798893}
\ No newline at end of file
+{"ELIQUIS": 3.289338891899045, "ENBREL": 8.851929051093096, "JANUVIA": 20.47425259671117, "ROTATEQ": 24.6155580379301, "SUBOXONE": 15.235203674969052, "null": 0.785631043393576}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8990.json
new file mode 100644
index 00000000000..1461494e85b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8990.json
@@ -0,0 +1 @@
+{"null": 1.92648097981972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8991.json
new file mode 100644
index 00000000000..249164cdd69
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8991.json
@@ -0,0 +1 @@
+{"null": 0.8832253996055756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8992.json
new file mode 100644
index 00000000000..54cc320f2e7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8992.json
@@ -0,0 +1 @@
+{"null": 0.6403715119876406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8993.json
new file mode 100644
index 00000000000..334c4bd06a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8993.json
@@ -0,0 +1 @@
+{"null": 0.8340297510290067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8994.json
new file mode 100644
index 00000000000..f59d013c3e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8994.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.5953751138435583, "AMGEVITA": 114.10303948665126, "ARAVA": 0.3924138194919178, "ATAZANAVIR": 2.287802065430796, "CIMZIA": 0.3456831323368519, "COMIRNATY": 2.531907282794148, "COSENTYX": 2.8415169868043657, "DEXAMETHASONE": 0.7336071344875592, "ELIQUIS": 0.2211592803299165, "ELLAONE": 24.28188440744931, "ENZALUTAMIDE": 7.058510180524085, "ESMYA": 15.667663094590742, "FASLODEX": 1.558655324022644, "FORSTEO": 2.919926359122316, "GARDASIL": 2.351586182780637, "IBRANCE": 0.4967348272478536, "JARDIANCE": 1.1940696469670598, "LANTUS": 0.4238567161545035, "MODERNA": 4.219909553365011, "NEULASTA": 4.292131070291559, "SIMPONI": 0.657232554369379, "SPIKEVAX": 1.0517934750732327, "STELARA": 0.6947242113848362, "STIVARGA": 1.0248813842411288, "SUBOXONE": 1.051113769063782, "SUTENT": 0.7926947723615579, "TOVIAZ": 4.3015003600387685, "TOZINAMERAN": 1.63047854914901, "VAXZEVRIA": 0.92649516436952, "XELJANZ": 0.9858989760407654, "XOFIGO": 4.166286162054194, "XTANDI": 1.4836342608290494, "ZARZIO": 25.0254999581374, "ZOSTAVAX": 0.7171072332496546, "null": 0.5789947676703835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8995.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8995.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8996.json
new file mode 100644
index 00000000000..94539344856
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8996.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.153750466302112, "ELIQUIS": 2.2378343305224697, "NOVOSEVEN": 96.6587143580445, "SPIKEVAX": 0.5699311237854437, "VAXZEVRIA": 1.1375033909607903, "null": 0.7048081980645688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8997.json
new file mode 100644
index 00000000000..6877123ad41
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8997.json
@@ -0,0 +1 @@
+{"BRAFTOVI": 1.5208275783228176, "BUDESONIDE": 0.5571030160715192, "BYETTA": 0.6379042972059173, "CELECOXIB": 2.08149580985475, "CICLOSPORIN": 0.5547613177709297, "CLOPIDOGREL": 1.5226247987249375, "COMIRNATY": 0.3042921312333822, "COSENTYX": 0.7627951915057933, "DABRAFENIB": 4.396866657824431, "DUOTRAV": 440.691716296677, "ELIQUIS": 0.5933263360606175, "EMPAGLIFLOZIN": 4.204358201331185, "EUCREAS": 101.41832654564612, "FASENRA": 1.1021498731856958, "FORSTEO": 0.635785492970157, "FORXIGA": 2.961940526699547, "GALVUS": 91.55724317758154, "IPILIMUMAB": 7.308260249922632, "IRBESARTAN": 5.745747651360943, "JANUMET": 6.3784340712788685, "JANUVIA": 39.925947295972136, "JARDIANCE": 1.422644359680488, "KEPPRA": 0.6519721026768684, "KEYTRUDA": 13.812657903100506, "LANTUS": 0.2188963091209198, "LIBTAYO": 24.370993007234965, "LINAGLIPTIN": 60.263806054218286, "METFORMIN": 186.7322681135001, "NIVOLUMAB": 8.214773220965009, "NOVONORM": 6.719764484327032, "ONGLYZA": 30.333624450156545, "OPDIVO": 4.0324965854222174, "PEMBROLIZUMAB": 17.850807819216865, "PLAVIX": 0.3114460638981615, "SHINGRIX": 0.91363038293772, "SITAGLIPTIN": 36.49822139696445, "SPIKEVAX": 0.2162994032868233, "STELARA": 1.9161830628307932, "TAMIFLU": 0.7741174897209571, "TOZINAMERAN": 0.6644128601077351, "TREMFYA": 4.183953122795231, "TRULICITY": 1.4079546859545906, "VAXZEVRIA": 0.1061262281770779, "VELMETIA": 20.90526843295087, "VILDAGLIPTIN": 350.16633668975106, "XARELTO": 2.415875461209798, "XOLAIR": 0.5103250866625857, "ZOSTAVAX": 0.6729737920613662, "null": 1.282921337013551}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8998.json
new file mode 100644
index 00000000000..52e2963e5db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8998.json
@@ -0,0 +1 @@
+{"ABATACEPT": 10.648022528173502, "ADALIMUMAB": 24.43029102165081, "APREMILAST": 2.069948935221054, "APREPITANT": 1.1514804146500084, "ARAVA": 98.9643399956502, "CELLCEPT": 0.327947136240254, "CIMZIA": 3.6582172553097054, "COMIRNATY": 0.0365204035023323, "COSENTYX": 0.8698796101126516, "EUCREAS": 2.385749495898354, "EXFORGE": 0.3781863640539429, "JANUVIA": 0.5334532745444914, "KEYTRUDA": 0.1848409917383928, "RITUXIMAB": 1.544868762912147, "SPIKEVAX": 0.0318901258221219, "STELARA": 0.3001985374166037, "TOZINAMERAN": 0.1086647821491245, "VAXZEVRIA": 0.0228019071865463, "null": 0.0616634385319856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8999.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/8999.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9.json
index 091960038d1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9.json
@@ -1 +1 @@
-{"ABATACEPT": 6.662661300633792, "ACETAMINOPHEN": 8.553063250381046, "ACETYLSALICYLIC": 11.778627414771696, "ADALIMUMAB": 10.639278442296764, "ADEMPAS": 2.095731150133332, "AGOMELATINE": 2.7221421031876054, "AIMOVIG": 1.0978879673533064, "ALISKIREN": 2.0949800380869155, "AMINOSALICYLIC": 1.28395375449227, "ANTIBIOTICS": 1.2526710334592954, "APIXABAN": 3.5800787348313428, "APREMILAST": 3.432034511827625, "APREPITANT": 11.366995864393528, "ARAVA": 14.712932504523572, "AUBAGIO": 1.2104743290110114, "BOSULIF": 1.365323258050035, "BRAFTOVI": 1.0504954335223138, "BRINTELLIX": 1.0793415675163276, "BYDUREON": 1.2192809026830869, "BYETTA": 1.1149974313165747, "CELECOXIB": 2.001633262400938, "CERTOLIZUMAB": 2.05684111721901, "CHAMPIX": 1.2131395385719697, "CIMZIA": 1.877331551008084, "CLOPIDOGREL": 1.108873476973133, "COSENTYX": 1.425852888444474, "DUAKLIR": 7.370304617312525, "DULAGLUTIDE": 1.6677954232192822, "DUPIXENT": 1.5823785838042983, "ELLAONE": 2.9974849293112027, "ENBREL": 1.6548009002929136, "ENZALUTAMIDE": 1.0015041443279604, "ERELZI": 2.635559617531791, "ESBRIET": 3.8408930056094417, "EUCREAS": 1.459379667772682, "EXJADE": 1.906179938454208, "FIRDAPSE": 1.5642081026810903, "HUMIRA": 1.8418771431330057, "IBRANCE": 1.456874198677257, "IBRUTINIB": 1.0003982136279197, "JANUMET": 1.206890906349529, "LEFLUNOMIDE": 2.440540793052435, "LIXIANA": 1.332939297800405, "LUPKYNIS": 2.7249268134251623, "MAYZENT": 8.203096816302743, "MELATONIN": 1.3560734064168491, "MISOPROSTOL": 3.078737307373143, "MULTAQ": 1.4290405964128687, "NINLARO": 1.9032982455337188, "OFEV": 2.292965435047865, "ORGALUTRAN": 3.942073738760807, "OVITRELLE": 2.522187518918283, "OZEMPIC": 3.226408112857848, "PIRFENIDONE": 2.295053504635189, "PRAMIPEXOLE": 3.025812279689638, "PROLIA": 1.924380633342188, "RITUXIMAB": 1.118836312347509, "RUBRACA": 1.1373202926655444, "RYBELSUS": 4.930057737658152, "SAXENDA": 1.6693943953716108, "SEMAGLUTIDE": 1.6151863385624396, "SUTENT": 1.5620036585851502, "TEDUGLUTIDE": 5.1277662364354, "TERIPARATIDE": 1.0036381726217445, "TICAGRELOR": 1.0453319801101686, "TRULICITY": 2.9599520689641263, "VEDOLIZUMAB": 1.274849001054159, "VELTASSA": 1.9381135024227512, "VICTOZA": 1.9647404788009528, "VOTRIENT": 1.4344303770859617, "XELJANZ": 1.7336623473361503, "XTANDI": 1.6881604217713837, "ZEJULA": 1.8000038662373348}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/90.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/90.json
index e6693f09b4b..604703bd3a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/90.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/90.json
@@ -1 +1 @@
-{"BUSULFAN": 14.107815542605156, "LACOSAMIDE": 86.28816720019404, "LEVETIRACETAM": 440.4716700362024}
\ No newline at end of file
+{"null": 0.8452258041202194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/900.json
index 764efea534b..35550198d88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/900.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/900.json
@@ -1 +1 @@
-{"null": 1.57529124026637}
\ No newline at end of file
+{"ABACAVIR": 0.9700589760430564, "AFINITOR": 1.4085234539211933, "ARAVA": 3.7238335482826463, "ARIPIPRAZOLE": 2.582162046839529, "AVAMYS": 6.17778342368496, "BRINTELLIX": 2.050391132463256, "COMIRNATY": 0.2978824121379134, "COSENTYX": 1.2036321556582703, "CYMBALTA": 1.3008224646257551, "ELLAONE": 9.00152179985779, "ESBRIET": 4.021021655977103, "FASENRA": 5.723265962537367, "GARDASIL": 1.6364036538295, "HUMALOG": 0.7996879837020607, "HUMIRA": 1.455685453352722, "IBRANCE": 3.0983942083397005, "INSULIN": 22.987079868674535, "KEYTRUDA": 0.5856439238258613, "LANTUS": 0.6548429147872934, "LYRICA": 1.499283655767139, "MEPOLIZUMAB": 6.22232581972877, "METFORMIN": 12.024749024022574, "NUCALA": 2.524921926964301, "PANTOPRAZOLE": 3.458481423518841, "PEGASYS": 2.1208590456183827, "PEGINTRON": 2.3135784099238754, "SAXENDA": 24.66198093097622, "SPIKEVAX": 0.2364232013483155, "SUTENT": 2.685414356921994, "TOZINAMERAN": 0.4838461763262839, "TRULICITY": 2.1474708143991514, "VAXZEVRIA": 0.6770574262037279, "VOTRIENT": 1.7259419189019245, "XELJANZ": 0.5535357866199427, "ZOSTAVAX": 1.3186701323612957, "ZYPREXA": 2.127353234777491, "null": 0.7942428036654642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9000.json
new file mode 100644
index 00000000000..432967e813b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9000.json
@@ -0,0 +1 @@
+{"null": 2.4667227586514}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9001.json
new file mode 100644
index 00000000000..bd89c12f46b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9001.json
@@ -0,0 +1 @@
+{"JARDIANCE": 59.218300194654674, "null": 0.9933595995489656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9002.json
new file mode 100644
index 00000000000..810defe30ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9002.json
@@ -0,0 +1 @@
+{"XIAPEX": 5477.844931612342, "null": 4.554535022231495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9003.json
new file mode 100644
index 00000000000..17b96bed1d1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9003.json
@@ -0,0 +1 @@
+{"VIAGRA": 92.49527136490808, "null": 2.060294160722219}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9004.json
new file mode 100644
index 00000000000..9fe6c3f056c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9004.json
@@ -0,0 +1 @@
+{"JARDIANCE": 80.91766949949618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9005.json
new file mode 100644
index 00000000000..6b14e5bc5b9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9005.json
@@ -0,0 +1 @@
+{"JARDIANCE": 39.35747841742409, "VIAGRA": 59.62887672071078, "null": 1.007369280660236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9006.json
new file mode 100644
index 00000000000..0146ad03027
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9006.json
@@ -0,0 +1 @@
+{"JARDIANCE": 129.7444449577052, "null": 0.5433282862058165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9007.json
new file mode 100644
index 00000000000..7ae1c99f27e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9007.json
@@ -0,0 +1 @@
+{"null": 1.6892141769044025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9008.json
new file mode 100644
index 00000000000..d67e7f69007
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9008.json
@@ -0,0 +1 @@
+{"FORXIGA": 43.652004320617706, "JARDIANCE": 99.10822215543, "VIAGRA": 37.17598490690295, "null": 0.9103064819764056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9009.json
new file mode 100644
index 00000000000..cfc3d3c56b9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9009.json
@@ -0,0 +1 @@
+{"SUTENT": 12.01035007198319, "null": 1.7288917642212205}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/901.json
index 5a0ac0001e6..8bc03940307 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/901.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/901.json
@@ -1 +1 @@
-{"null": 2.2306810060740507}
\ No newline at end of file
+{"null": 2.0363559482475493}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9010.json
new file mode 100644
index 00000000000..1e7f378b2f0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9010.json
@@ -0,0 +1 @@
+{"XIAPEX": 2783.614869252263, "null": 5.839365350190303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9011.json
new file mode 100644
index 00000000000..57c3cf6120d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9011.json
@@ -0,0 +1 @@
+{"ELIQUIS": 8.34732294998155, "JARDIANCE": 6.311910936753114, "SUTENT": 3.41170810043502, "VAXZEVRIA": 0.2436358141175021, "VIAGRA": 173.79974977648993, "null": 1.0219297383160753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9012.json
new file mode 100644
index 00000000000..e0dd9ff5d70
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9012.json
@@ -0,0 +1 @@
+{"JARDIANCE": 150.98710051426957, "null": 0.4205070839252257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9013.json
new file mode 100644
index 00000000000..c0df0942d2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9013.json
@@ -0,0 +1 @@
+{"null": 3.203720978667747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9014.json
new file mode 100644
index 00000000000..0652ad23af8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9014.json
@@ -0,0 +1 @@
+{"VIAGRA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9015.json
new file mode 100644
index 00000000000..842a7cb109d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9015.json
@@ -0,0 +1 @@
+{"JARDIANCE": 8.285664727147765, "null": 2.141852244075787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9016.json
new file mode 100644
index 00000000000..345f343827e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9016.json
@@ -0,0 +1 @@
+{"null": 2.588873808515698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9017.json
new file mode 100644
index 00000000000..8c114adcdaa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9017.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1058925793789234, "FORXIGA": 9.51480003623119, "JARDIANCE": 11.244035096081188, "SILDENAFIL": 16.685893859860872, "SPIKEVAX": 0.2128448769474482, "SUTENT": 1.2131345543849583, "VIAGRA": 423.2955968071438, "XIAPEX": 436.1699933696145, "null": 1.0443683181507182}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9018.json
new file mode 100644
index 00000000000..53a90150e33
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9018.json
@@ -0,0 +1 @@
+{"FORXIGA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9019.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9019.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/902.json
index 81ee28f6d57..c1a7a6312b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/902.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/902.json
@@ -1 +1 @@
-{"ABILIFY": 14.41324561334187, "BRINTELLIX": 24.504277329499896, "ZYPREXA": 5.963426213338195, "null": 1.8216899779654017}
\ No newline at end of file
+{"null": 8.44563404508154}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9020.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9020.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9021.json
new file mode 100644
index 00000000000..af987b156e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9021.json
@@ -0,0 +1 @@
+{"null": 10.494590614948134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9022.json
new file mode 100644
index 00000000000..6b6e56131e5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9022.json
@@ -0,0 +1 @@
+{"JARDIANCE": 27.86318160148613, "SPIKEVAX": 0.2534487318766875, "TOZINAMERAN": 0.6946281881921803, "VIAGRA": 74.23997461824624, "XIAPEX": 1571.5565979304415, "null": 1.9210891840239337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9023.json
new file mode 100644
index 00000000000..14f7ac795b6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9023.json
@@ -0,0 +1 @@
+{"JARDIANCE": 14.181533680909109, "null": 1.8261959142147817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9024.json
new file mode 100644
index 00000000000..fbf0b2fd620
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9024.json
@@ -0,0 +1 @@
+{"VIAGRA": 260.1887563605293, "null": 1.7106588076305962}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9025.json
new file mode 100644
index 00000000000..3a7371af04c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9025.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1639102575161837, "VAXZEVRIA": 1.900893680543188, "null": 0.3992861189850491}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9026.json
new file mode 100644
index 00000000000..ad74792f2a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9026.json
@@ -0,0 +1 @@
+{"NUCALA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9027.json
new file mode 100644
index 00000000000..dfb8d2b5113
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9027.json
@@ -0,0 +1 @@
+{"FORXIGA": 15.07728781427142, "JARDIANCE": 21.24428873171295, "VIAGRA": 207.54539720643365, "null": 2.0631929235347752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9028.json
new file mode 100644
index 00000000000..60288bac0a5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9028.json
@@ -0,0 +1 @@
+{"JARDIANCE": 23.736254779586226, "VIAGRA": 61.48212710937026, "null": 2.7195031935280944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9029.json
new file mode 100644
index 00000000000..fd0151db097
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9029.json
@@ -0,0 +1 @@
+{"PEMBROLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/903.json
index 721e8184a9d..e90cb3f68f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/903.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/903.json
@@ -1 +1 @@
-{"AZILECT": 344.266326098229, "null": 1.5181351722250414}
\ No newline at end of file
+{"null": 3.788888232385263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9030.json
new file mode 100644
index 00000000000..91e9d2f9f21
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9030.json
@@ -0,0 +1 @@
+{"ARAVA": 0.2874134707194666, "AVONEX": 51.30095304697913, "CLOPIDOGREL": 5.358638641868724, "COSENTYX": 4.723350147339607, "EFAVIRENZ": 14.573759240115283, "ELIQUIS": 2.700314983387932, "EXFORGE": 5.396325214414675, "EXJADE": 3.2601980597325584, "IBUPROFEN": 4.524677504824427, "PEGINTRON": 1.8610477063636848, "PLAVIX": 4.693225092521799, "ZOSTAVAX": 2.7325290081992515, "null": 2.544315476308736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9031.json
new file mode 100644
index 00000000000..2bdf13358e7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9031.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 24.457966352992624, "ELIQUIS": 4.345013279208599, "ENBREL": 36.68794421085611, "PLAVIX": 27.738932481006287, "TOZINAMERAN": 0.9635948987037796, "VAXZEVRIA": 0.1563353252632238, "XARELTO": 20.91946217650754, "null": 0.799053783201311}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9032.json
new file mode 100644
index 00000000000..d8e740d9524
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9032.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": 31.97048381409298, "null": 2.064126026423565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9033.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9033.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9034.json
new file mode 100644
index 00000000000..4b2e871abb4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9034.json
@@ -0,0 +1 @@
+{"AVANDIA": 30.486712478463133, "CLOPIDOGREL": 14.547138415030242, "ELIQUIS": 15.62128600969008, "null": 0.5741550080953235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9035.json
new file mode 100644
index 00000000000..3ba86e819ac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9035.json
@@ -0,0 +1 @@
+{"null": 1.4983953535340335}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9036.json
new file mode 100644
index 00000000000..f207b6e832e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9036.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 8.080046018362172, "null": 0.5231175324486331}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9037.json
new file mode 100644
index 00000000000..6be5580992a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9037.json
@@ -0,0 +1 @@
+{"null": 2.5976518060301648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9038.json
new file mode 100644
index 00000000000..e7bc0e0ccfa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9038.json
@@ -0,0 +1 @@
+{"AFINITOR": 1.3906088782233723, "ALIMTA": 3.5968138033072456, "BEVACIZUMAB": 2.888948422777652, "BUPIVACAINE": 45.96755714823983, "CABOMETYX": 3.67665349430877, "COMIRNATY": 3.1626332399154444, "CYMBALTA": 0.7989286301876982, "DEXAMETHASONE": 1.050664240117235, "ELIQUIS": 0.4764029608325542, "ENTRESTO": 0.849079800464813, "FENTANYL": 1.7904727421922506, "FIRDAPSE": 7.632333974926924, "GARDASIL": 0.6960318690616571, "JARDIANCE": 0.5659482731827677, "JEVTANA": 8.830975425837613, "KEPPRA": 0.8031881100009035, "KETOCONAZOLE": 30.796717521955948, "KEYTRUDA": 0.945045785391093, "LEVETIRACETAM": 1.368260884793688, "LONSURF": 11.054507460595712, "NEXAVAR": 2.4707477031365843, "OLANZAPINE": 1.0226516898684015, "OPDIVO": 3.0128219635834146, "PEMBROLIZUMAB": 2.68896051844864, "SHINGRIX": 0.8558641119104499, "SPIKEVAX": 1.2361129458815208, "STIVARGA": 3.938495428818477, "SUTENT": 1.1673665037557948, "TOVIAZ": 6.270564642182218, "TWINRIX": 6.010888894213508, "VAXZEVRIA": 0.3089394070276741, "VOTRIENT": 1.741413156015736, "XTANDI": 2.2526829574376426, "null": 0.5126910627603644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9039.json
new file mode 100644
index 00000000000..de7fbba5442
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9039.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.303907134007344, "HYDROCORTISONE": 80.00122174490629, "MEPOLIZUMAB": 40.96829894077768, "OMALIZUMAB": 182.67388831611316, "null": 0.2710483053475109}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/904.json
index d4fff52e377..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/904.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/904.json
@@ -1 +1 @@
-{"null": 1.3948971131320724}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9040.json
new file mode 100644
index 00000000000..ab9942bdc32
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9040.json
@@ -0,0 +1 @@
+{"YESCARTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9041.json
new file mode 100644
index 00000000000..608eaccf39b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9041.json
@@ -0,0 +1 @@
+{"ATRIPLA": 0.212644172571459, "COMIRNATY": 2.663175050303158, "CYMBALTA": 1.7622591422073246, "HUMALOG": 0.5346002713452401, "HYDROCORTISONE": 5.089271158083681, "MODERNA": 2.688440220452068, "OCRELIZUMAB": 3.848160186375156, "SHINGRIX": 0.9339204485826252, "SPIKEVAX": 1.8970010678388112, "TOZINAMERAN": 4.129747993876764, "VAXZEVRIA": 3.2701739819074604, "ZOSTAVAX": 0.9319681420207516, "null": 0.1692775504215021}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9042.json
new file mode 100644
index 00000000000..4a07d6bf059
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9042.json
@@ -0,0 +1 @@
+{"EMTRICITABINE": 1588.5393538138464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9043.json
new file mode 100644
index 00000000000..c1257741cb3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9043.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7077217440412694, "null": 0.2407685676119921}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9044.json
new file mode 100644
index 00000000000..24d84947a5b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9044.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4231750466082929, "ELIQUIS": 12.964343658125305, "null": 0.3853883360751668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9045.json
new file mode 100644
index 00000000000..420170edbe4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9045.json
@@ -0,0 +1 @@
+{"ADCIRCA": 6.914063135777443, "ADEMPAS": 3.158395033791112, "AFINITOR": 2.946212464481739, "ALEMTUZUMAB": 2.932227881613545, "ALIMTA": 2.409438826500479, "AMBRISENTAN": 4.064654600447698, "APIXABAN": 0.4035001885424529, "ARAVA": 0.0602226612430205, "AVANDAMET": 3.9064900829692415, "AVANDIA": 5.3884355503676105, "AVASTIN": 0.5476587674754441, "BENLYSTA": 1.8590919452515469, "BEVACIZUMAB": 1.2351482356350332, "BOSULIF": 17.401747880928824, "BRILIQUE": 1.1364034191629286, "BUSULFAN": 5.191159104314595, "CABOMETYX": 1.0592877748803198, "CAPECITABINE": 0.8110090196135491, "CELLCEPT": 1.396324108019945, "CICLOSPORIN": 1.1094141076482338, "CIMZIA": 0.1883270020158954, "CLOPIDOGREL": 0.9122861670736284, "COMBIVIR": 1.5533354275799425, "COMIRNATY": 1.222074834607147, "CYMBALTA": 0.2205836058290811, "CYTARABINE": 1.791505837284506, "DEXAMETHASONE": 1.052653193209332, "DOCETAXEL": 0.7646755502241077, "DOLUTEGRAVIR": 6.064657975868012, "ELIQUIS": 1.531777555283375, "EMTRICITABINE": 4.316504174223839, "ENTRESTO": 0.9152898725674036, "ENTYVIO": 0.9558023303486264, "ESBRIET": 1.179485486694653, "ESOMEPRAZOLE": 2.556949807786574, "EXJADE": 0.9109386955773184, "FASLODEX": 1.2107323197447637, "FENTANYL": 0.2635581730275688, "FILGRASTIM": 2.1902240367957204, "FULVESTRANT": 1.8607207374859729, "GARDASIL": 0.2541608492181956, "GEFITINIB": 3.7159938383499753, "GLIVEC": 2.972249723445658, "HERCEPTIN": 3.5529399031931543, "HUMALOG": 3.0704930126112697, "HUMIRA": 0.4381746858364658, "IBRANCE": 0.9784281290834532, "IBUPROFEN": 0.5623403503870188, "ICLUSIG": 7.548719133276303, "IMATINIB": 3.606468609102656, "INLYTA": 1.249407633224905, "INSULIN": 1.2038517872041357, "IPILIMUMAB": 1.1243101221626934, "IRESSA": 3.785930921858004, "JAKAVI": 1.6190869061344466, "JANUMET": 0.3466164228408901, "JANUVIA": 0.932862965794127, "JARDIANCE": 0.4248382722496772, "KEYTRUDA": 3.4180337757759487, "KYMRIAH": 0.8276409639459357, "KYPROLIS": 2.608800387345995, "LANTUS": 0.5194912460157483, "LEVETIRACETAM": 0.6635927097382007, "LEVOFLOXACIN": 0.7256407375266893, "MACITENTAN": 9.219666598060046, "MEKINIST": 0.6697857347439571, "METHOTREXATE": 0.691353634091859, "MICARDIS": 0.7639782344907727, "MIDAZOLAM": 1.333265200978013, "MODERNA": 0.396588412385616, "MULTAQ": 2.284978435869312, "MYCOPHENOLATE": 1.4554613491354365, "NEXAVAR": 0.4154594322267697, "NILOTINIB": 9.851013085097676, "NOXAFIL": 2.384937464532678, "NPLATE": 1.0149385360882628, "OLANZAPINE": 0.7778056599963338, "OPDIVO": 1.3746153210683116, "OPSUMIT": 5.225211992309507, "PACLITAXEL": 2.0323053314220214, "PEGASYS": 0.8782673388894852, "PEGINTRON": 0.4657391019377541, "PEMBROLIZUMAB": 2.186564009862297, "PEMETREXED": 1.5894934622176138, "PLAVIX": 0.6268638354364523, "RAPAMUNE": 5.731998990939738, "REVATIO": 4.303318454889912, "RIBAVIRIN": 0.6672742733692333, "RINVOQ": 0.5307372787848034, "RITUXIMAB": 0.408034725112521, "RUBRACA": 1.2410355721072066, "SILDENAFIL": 3.634402074554965, "SIMPONI": 0.9394421377582968, "SOLIRIS": 2.040191650791764, "SPIKEVAX": 0.6510803585799348, "SPRYCEL": 37.583723789601954, "STELARA": 0.569562180030695, "STIVARGA": 0.5196053874829627, "SUTENT": 2.1272215150446274, "TAGRISSO": 3.709610246804262, "TASIGNA": 8.402646445166855, "TORISEL": 3.248567297118669, "TOZINAMERAN": 0.8844148805237688, "TRACLEER": 4.794408175707647, "TRACTOCILE": 11.84002971292918, "TRELEGY": 0.8248510538879067, "TRISENOX": 9.680716121109253, "VAXZEVRIA": 0.1949069971625116, "VELTASSA": 2.061419099827796, "VFEND": 0.5577084717121072, "VOTRIENT": 1.923938371063147, "XALKORI": 6.813298819426448, "XARELTO": 1.2828513416310003, "XELJANZ": 0.4935434965270864, "XOLAIR": 0.6670346260280794, "XTANDI": 0.3129021137584815, "YERVOY": 1.5049257153543871, "ZELBORAF": 3.235146468661178, "ZOSTAVAX": 0.4194429768352864, "ZYPREXA": 0.5034482082638351, "null": 0.6425850771639615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9046.json
new file mode 100644
index 00000000000..371213a3c94
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9046.json
@@ -0,0 +1 @@
+{"ISENTRESS": 302.2222330162271, "null": 0.6470135058058539}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9047.json
new file mode 100644
index 00000000000..7415408e16d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9047.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.625161173870346, "null": 0.4265354194532689}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9048.json
new file mode 100644
index 00000000000..55967e09bb8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9048.json
@@ -0,0 +1 @@
+{"APIXABAN": 9.748831699557398, "BRILIQUE": 32.558357402857006, "CLOPIDOGREL": 17.03384572616172, "COMIRNATY": 0.1426669913446206, "ELIQUIS": 25.00164545251756, "PLAVIX": 14.489711129154248, "SPIKEVAX": 0.2113979443607502, "TICAGRELOR": 16.068820801386895, "VAXZEVRIA": 0.1233202619015088, "XARELTO": 24.25815085531806, "null": 0.9444996345134696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9049.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9049.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/905.json
index e159f83004e..c7722da420e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/905.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/905.json
@@ -1 +1 @@
-{"null": 1.9095793382959527}
\ No newline at end of file
+{"null": 1.9046738537938133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9050.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9050.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9051.json
new file mode 100644
index 00000000000..df8dea69fcb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9051.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.3680778524137476, "SPIKEVAX": 1.670150940814204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9052.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9052.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9053.json
new file mode 100644
index 00000000000..a728294f45d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9053.json
@@ -0,0 +1 @@
+{"ABATACEPT": 3.060557010682567, "ABILIFY": 0.1251996801717247, "ACLASTA": 3.342855518431429, "ADALIMUMAB": 5.686404094315347, "AIMOVIG": 0.1147739836951057, "ALIMTA": 0.2499770399438442, "APIXABAN": 0.99520318040823, "APREMILAST": 5.153502246351762, "ARAVA": 9.891106785388205, "AVANDIA": 0.3450071445680208, "BENLYSTA": 1.5276305123054568, "BOSULIF": 0.9846020779292416, "BUSILVEX": 3.152704432560703, "CELLCEPT": 0.2253818574995464, "CHAMPIX": 0.111540080734324, "CICLOSPORIN": 0.0805753689214385, "CIMZIA": 1.0013814842027966, "COMIRNATY": 4.620121419397268, "COSENTYX": 0.8949306101168678, "CYTARABINE": 0.2154478966772942, "ELIQUIS": 0.1375980451868427, "ENBREL": 0.4391085113501263, "ENTYVIO": 0.6055598224005924, "ERELZI": 3.793092758088475, "FORSTEO": 0.0997774444989265, "GARDASIL": 0.0977279000184393, "HUMIRA": 0.3232389135534924, "IBUPROFEN": 0.5902872800357593, "ICLUSIG": 0.4141403773621457, "ISENTRESS": 0.5719023008011989, "KEYTRUDA": 0.3923942185351277, "KYPROLIS": 0.8890012742099462, "METHOTREXATE": 0.3031826712227449, "MODERNA": 2.076286857995606, "NILOTINIB": 2.1593319854123867, "OLANZAPINE": 0.0859660358432536, "OPDIVO": 0.2427416333817381, "PEGASYS": 0.512065537869877, "PEGINTRON": 0.1598711346473586, "PEMBROLIZUMAB": 1.0315792253003928, "REMICADE": 0.7429278820155854, "RITUXIMAB": 0.977607442983901, "ROACTEMRA": 0.1860540504827978, "SHINGRIX": 0.3974938939285858, "SIMPONI": 0.335887128471657, "SOLIRIS": 0.1422871996611223, "SPIKEVAX": 1.8336556615872144, "SPRYCEL": 1.225344359826941, "STELARA": 0.7184799263299168, "SUTENT": 0.1118837819067847, "TASIGNA": 0.5426707217379307, "TOZINAMERAN": 2.795416731156919, "TRACLEER": 0.1608039549315278, "VAXZEVRIA": 0.303128122760365, "XELJANZ": 0.2550357684741986, "XOLAIR": 0.2764138468719004, "ZELBORAF": 0.7728700369520851, "null": 0.1335834947833755}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9054.json
new file mode 100644
index 00000000000..f1315de5a5b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9054.json
@@ -0,0 +1 @@
+{"null": 2.990564827583219}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9055.json
new file mode 100644
index 00000000000..62b1b804a4f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9055.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5428486011231963, "null": 0.8410900516025812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9056.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9056.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9057.json
new file mode 100644
index 00000000000..52d20288e5b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9057.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.0158906644435006}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9058.json
new file mode 100644
index 00000000000..6e06123c033
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9058.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 96.006769445434}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9059.json
new file mode 100644
index 00000000000..bd552fc4a5a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9059.json
@@ -0,0 +1 @@
+{"null": 0.6579458467610275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/906.json
index ad3312cc32f..3bacc7ea541 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/906.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/906.json
@@ -1 +1 @@
-{"SOLIRIS": 46.76781484618534}
\ No newline at end of file
+{"COMIRNATY": 0.1625867796203709, "FORSTEO": 16.79240931345673, "NEULASTA": 69.43368450228891, "VAXZEVRIA": 1.657274213188857, "null": 1.7480415472151292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9060.json
new file mode 100644
index 00000000000..38f1e8f9302
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9060.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.621617224607905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9061.json
new file mode 100644
index 00000000000..7d544ed2ded
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9061.json
@@ -0,0 +1 @@
+{"CYTARABINE": 200.66396200307184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9062.json
new file mode 100644
index 00000000000..431516cee52
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9062.json
@@ -0,0 +1 @@
+{"TENOFOVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9063.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9063.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9064.json
new file mode 100644
index 00000000000..fbbe81a0bd3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9064.json
@@ -0,0 +1 @@
+{"ABILIFY": 30.648967397128345, "KEPPRA": 9.592151869294383, "null": 1.0144342994724391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9065.json
new file mode 100644
index 00000000000..b3b1731035c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9065.json
@@ -0,0 +1 @@
+{"FORXIGA": 54.73198283284652, "JARDIANCE": 76.49295529714693, "null": 0.1296972353929584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9066.json
new file mode 100644
index 00000000000..3f20e252697
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9066.json
@@ -0,0 +1 @@
+{"null": 0.8725085263608586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9067.json
new file mode 100644
index 00000000000..38420feea57
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9067.json
@@ -0,0 +1 @@
+{"JARDIANCE": 98.36326770400464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9068.json
new file mode 100644
index 00000000000..a502b0bb0c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9068.json
@@ -0,0 +1 @@
+{"null": 1.8970760744355095}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9069.json
new file mode 100644
index 00000000000..d9705340cec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9069.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2393975229113164, "HYDROCORTISONE": 80.02663729094438, "JARDIANCE": 16.138380132977797, "LEVOFLOXACIN": 20.50949321124564, "SUTENT": 4.01092266521451, "null": 0.919618164185074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/907.json
index e7f869384cb..1221e7f7f98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/907.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/907.json
@@ -1 +1 @@
-{"NPLATE": 626.922686658039}
\ No newline at end of file
+{"ALDARA": 58.905979843581655, "BUPRENORPHINE": 5.44373139349514, "EVRA": 20.17642007110197, "QUTENZA": 450.4875028600421, "null": 11.791989365351192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9070.json
new file mode 100644
index 00000000000..a49e974b0a3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9070.json
@@ -0,0 +1 @@
+{"JARDIANCE": 384.5501977918016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9071.json
new file mode 100644
index 00000000000..939e1878b67
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9071.json
@@ -0,0 +1 @@
+{"null": 0.5404806822656967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9072.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9072.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9073.json
new file mode 100644
index 00000000000..5412e8389a4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9073.json
@@ -0,0 +1 @@
+{"null": 1.7406942638859886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9074.json
new file mode 100644
index 00000000000..7a1af2cdcbd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9074.json
@@ -0,0 +1 @@
+{"ATRIPLA": 3.0587385859631846, "SUNITINIB": 259.7499988829635, "TRUVADA": 2.6612894532819773, "null": 0.5330639749201748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9075.json
new file mode 100644
index 00000000000..c001d5d2431
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9075.json
@@ -0,0 +1 @@
+{"BONVIVA": 60.2509976744506, "CICLOSPORIN": 3.0888924627922267, "COMIRNATY": 0.2714371873548715, "FORSTEO": 4.84510271618761, "SIMPONI": 3.29068090757372, "STELARA": 6.378619225092533, "SUTENT": 1.5109367451765363, "null": 0.8582927155788521}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9076.json
new file mode 100644
index 00000000000..db66722fa30
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9076.json
@@ -0,0 +1 @@
+{"AVAMYS": 16.524549384580677, "COMIRNATY": 0.8010620079851689, "SPIKEVAX": 0.3177469788548118, "VAXZEVRIA": 0.2494012256518663, "null": 1.3330072248967284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9077.json
new file mode 100644
index 00000000000..3cf5c6c131a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9077.json
@@ -0,0 +1 @@
+{"null": 0.5338888889812123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9078.json
new file mode 100644
index 00000000000..e2a2c50d6f3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9078.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.1089105216427537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9079.json
new file mode 100644
index 00000000000..b86aa0dff3d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9079.json
@@ -0,0 +1 @@
+{"null": 0.7775215640317513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/908.json
index ba35762f5b7..e631993b193 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/908.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/908.json
@@ -1 +1 @@
-{"null": 9.224438259435836}
\ No newline at end of file
+{"null": 0.8747763506310584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9080.json
new file mode 100644
index 00000000000..15197175365
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9080.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3756205553547491, "ELIQUIS": 11.154371246922926, "PLAVIX": 11.84825892951002, "VAXZEVRIA": 0.5043537659716424, "null": 1.0772850376862364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9081.json
new file mode 100644
index 00000000000..45f808d888d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9081.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5455154050978042, "VAXZEVRIA": 1.522648967842349, "null": 0.955922073788854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9082.json
new file mode 100644
index 00000000000..4aab17dd23b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9082.json
@@ -0,0 +1 @@
+{"null": 2.1571591563082437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9083.json
new file mode 100644
index 00000000000..4bcb9704910
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9083.json
@@ -0,0 +1 @@
+{"ALIMTA": 2.177206815011948, "AYVAKYT": 267.8413402999365, "BUDESONIDE": 2.34994866818574, "CLOPIDOGREL": 0.7345402036280212, "COMIRNATY": 0.7771753410306689, "GARDASIL": 0.4726144812514917, "GLIVEC": 10.545992373431394, "HUMIRA": 1.264144575909972, "IBUPROFEN": 3.1811899939487613, "IMATINIB": 9.392224739045629, "JARDIANCE": 0.7238458613440933, "LYRICA": 1.1496393822339257, "OLANZAPINE": 0.9392856883385616, "PEGASYS": 0.3525336075992698, "RASILEZ": 7.242809684882715, "SPIKEVAX": 0.0957772772099215, "SUTENT": 4.99531649598575, "TASIGNA": 2.5761675493661222, "TOZINAMERAN": 0.2757426264240215, "VAXZEVRIA": 0.1609229720034938, "XOLAIR": 1.64690761392896, "null": 2.7101806384498315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9084.json
new file mode 100644
index 00000000000..121d1c3ebf3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9084.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.2536719983447902, "VAXZEVRIA": 0.7612324043982651, "null": 0.7240872251291129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9085.json
new file mode 100644
index 00000000000..d11bd6a70e9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9085.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1749603688048105, "DEXAMETHASONE": 1.374638632658756, "ENTECAVIR": 21.459340586837158, "ENTRESTO": 1.135380293565042, "JARDIANCE": 0.6681845201055324, "MMRVAXPRO": 1.2286912760618982, "NIMENRIX": 3.744682457915451, "SPIKEVAX": 0.9230346213879216, "SUTENT": 1.2010135236239796, "TAMIFLU": 2.1614824500275764, "TOZINAMERAN": 2.258499563306972, "VAXZEVRIA": 0.8137520323854808, "XOLAIR": 1.01517561758835, "null": 1.751508889160173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9086.json
new file mode 100644
index 00000000000..78e9d5c1be6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9086.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2500001859835694, "VFEND": 30.14666225107935, "VORICONAZOLE": 2483.749219642236, "null": 0.0977837572582218}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9087.json
new file mode 100644
index 00000000000..5861639d9b7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9087.json
@@ -0,0 +1 @@
+{"MYCOPHENOLATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9088.json
new file mode 100644
index 00000000000..3da59600997
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9088.json
@@ -0,0 +1 @@
+{"VORICONAZOLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9089.json
new file mode 100644
index 00000000000..e36ac4c095e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9089.json
@@ -0,0 +1 @@
+{"null": 0.9814585982551852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/909.json
index fdc709b5b14..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/909.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/909.json
@@ -1 +1 @@
-{"null": 3.133680745964011}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9090.json
new file mode 100644
index 00000000000..bc557455060
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9090.json
@@ -0,0 +1 @@
+{"null": 2.2778563971848893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9091.json
new file mode 100644
index 00000000000..c6c7b3c1a51
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9091.json
@@ -0,0 +1 @@
+{"null": 3.091661048238552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9092.json
new file mode 100644
index 00000000000..1bd3038cc78
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9092.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 20.582240858300995, "null": 0.437357311049982}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9093.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9093.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9094.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9094.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9095.json
new file mode 100644
index 00000000000..6ff5007b224
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9095.json
@@ -0,0 +1 @@
+{"AVANDIA": 3.595742729762115, "BOSULIF": 8.180599131483248, "BOSUTINIB": 45.33485123398948, "CLOPIDOGREL": 2.481007649072837, "COMIRNATY": 0.2524198867842779, "ELIQUIS": 2.7639154550414253, "FORXIGA": 3.3483885916745493, "HUMALOG": 1.477982512223713, "ICLUSIG": 69.0623561839334, "IMATINIB": 15.358808374368612, "JANUMET": 2.3468143560826324, "JARDIANCE": 1.933626645750012, "LANTUS": 0.6025136424046988, "NILOTINIB": 250.70679987256895, "PLAVIX": 4.5463611444110335, "SPIKEVAX": 0.1164898853206775, "SPRYCEL": 5.745206768347362, "TASIGNA": 239.27440434128096, "VAXZEVRIA": 0.0688162585924712, "ZOSTAVAX": 3.8648933630298745, "null": 0.4723096081775762}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9096.json
new file mode 100644
index 00000000000..06de27c2ea2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9096.json
@@ -0,0 +1 @@
+{"null": 0.6498094362430618}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9097.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9097.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9098.json
new file mode 100644
index 00000000000..2235ef1712f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9098.json
@@ -0,0 +1 @@
+{"null": 0.8736672188562427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9099.json
new file mode 100644
index 00000000000..ef85477d23b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9099.json
@@ -0,0 +1 @@
+{"AMINOSALICYLIC": 7.063615947994778, "CLOPIDOGREL": 2.369924421562978, "COMIRNATY": 0.3243865259268134, "ELIQUIS": 2.095084439312945, "ENOXAPARIN": 14.153750710791185, "HUMALOG": 3.4567949964399074, "ICLUSIG": 12.879366070197138, "JARDIANCE": 4.522484260230947, "LANTUS": 1.4738993294912202, "NILOTINIB": 46.78502574437142, "PLAVIX": 6.298263513127649, "SPIKEVAX": 0.2713601863313014, "TASIGNA": 55.3983701859738, "VAXZEVRIA": 0.3666952492970559, "XARELTO": 11.790499690839017, "null": 0.7712144392504636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/91.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/91.json
index 72c9d54ef13..14ed2f182ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/91.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/91.json
@@ -1 +1 @@
-{"AMIKACIN": 95.3788230832942, "CASPOFUNGIN": 47.24532103793901, "CICLOSPORIN": 17.05424707425568, "TIGECYCLINE": 279.0412634880268}
\ No newline at end of file
+{"COMIRNATY": 0.0757700058056892, "CYMBALTA": 6.353422325430627, "DULOXETINE": 16.234975907081346, "EPIVIR": 28.384495193864304, "LATUDA": 14.08647118210864, "OLANZAPINE": 5.885712720504399, "ZYPREXA": 6.440529739071105, "null": 2.647814235754827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/910.json
index d553b05c2c3..29dcd75367d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/910.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/910.json
@@ -1 +1 @@
-{"null": 11.077732316375805}
\ No newline at end of file
+{"null": 8.631669615362318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9100.json
new file mode 100644
index 00000000000..0f48a4f50ac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9100.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1668706222547358, "ICLUSIG": 62.84336830361444, "NILOTINIB": 363.3881513720295, "TASIGNA": 186.3656410130432, "null": 0.258472122236115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9101.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9101.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9102.json
new file mode 100644
index 00000000000..5287c9241f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9102.json
@@ -0,0 +1 @@
+{"AERIUS": 17.712272065609987, "CLOPIDOGREL": 2.861925089651573, "COMIRNATY": 0.919023445680486, "ELIQUIS": 3.6474503685830815, "FASLODEX": 6.61675890822374, "ICLUSIG": 11.320424895315822, "NOVOSEVEN": 137.68330558704656, "SPIKEVAX": 0.4361640696898723, "STELARA": 1.8731794768909933, "TASIGNA": 10.040468928137072, "VAXZEVRIA": 1.817916862210588, "null": 0.6140685963914887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9103.json
new file mode 100644
index 00000000000..bcc24956b82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9103.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.193651490787928, "SPIKEVAX": 1.253289668835766, "VAXZEVRIA": 1.706014730390596, "null": 0.7212050911004876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9104.json
new file mode 100644
index 00000000000..b212979a18a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9104.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.863326379806744, "APIDRA": 0.6497312509715564, "APROVEL": 1.765501891117056, "ARAVA": 0.0353660687462361, "AUBAGIO": 0.7767086899288606, "AVAMYS": 0.7122767787119207, "BRILIQUE": 0.697040425264009, "BYDUREON": 0.8737485907913503, "CHAMPIX": 0.2182764124618319, "CLOPIDOGREL": 0.5274375939783419, "COAPROVEL": 1.8653477062263963, "COMIRNATY": 1.439029685317003, "CYMBALTA": 0.3477701234774538, "DEXAMETHASONE": 0.5771221225825153, "DULOXETINE": 0.9673242096687096, "EDOXABAN": 18.575144133966177, "ELIQUIS": 0.632142907479289, "ENBREL": 0.5339288546416824, "ENTRESTO": 0.9838734225836576, "EXFORGE": 0.6631423170281032, "FAMPYRA": 1.0222751823549483, "FASLODEX": 0.4521546409452145, "FIRDAPSE": 5.685801884561881, "FLEBOGAMMA": 1.969869594625232, "FORSTEO": 0.7112095444869954, "FORXIGA": 0.6122476070273062, "GARDASIL": 4.1912639708944885, "HUMALOG": 0.2625508117295422, "HUMIRA": 0.4326781900953931, "HYDROCORTISONE": 4.130915360483504, "IBRANCE": 0.3152120690334968, "IBUPROFEN": 0.3601965172107634, "IRBESARTAN": 1.2507503062703988, "JANUMET": 0.973497815135802, "JANUVIA": 0.3483861561187805, "JARDIANCE": 0.368637247991825, "KALETRA": 1.1668652509241624, "KEPPRA": 0.3321763924304222, "KEYTRUDA": 0.1213175067584581, "KIOVIG": 3.158261590466468, "LANTUS": 0.2535835033435593, "LEVOFLOXACIN": 0.7525154640625141, "LOPINAVIR": 6.468816713693809, "LYRICA": 0.8444173206653612, "MICARDIS": 1.1203122576952602, "MMRVAXPRO": 0.2870876281169793, "MODERNA": 0.3916131143850331, "OCRELIZUMAB": 2.360016978279293, "OPTIMARK": 0.6848507097914146, "PEGASYS": 0.3193826391803653, "PLAVIX": 0.3342689151364906, "PRIVIGEN": 0.9180630283273844, "PROPRANOLOL": 3.412292079338455, "SHINGRIX": 0.6637290111852479, "SPIKEVAX": 1.1400800881100452, "STELARA": 0.4884638514465773, "SUTENT": 0.2666494499102209, "SYNAGIS": 0.8790902680079163, "TASIGNA": 0.9110298927334792, "TOZINAMERAN": 1.9766961827321488, "TWINRIX": 1.7100734707233871, "VALSARTAN": 1.9002037237168763, "VAXZEVRIA": 2.963682977807704, "VOTRIENT": 0.4047108243071206, "XELJANZ": 0.3693879289577343, "XOLAIR": 0.2371991127584463, "XTANDI": 0.2438987237337533, "ZYPREXA": 0.1747863474435083, "null": 0.8464038139345083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9105.json
new file mode 100644
index 00000000000..9804c6054cd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9105.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7498313222257734, "ELIQUIS": 6.737034262560567, "SPIKEVAX": 0.2848913970671465, "VAXZEVRIA": 0.8861447344640717, "null": 0.8827802197393796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9106.json
new file mode 100644
index 00000000000..5f97310265c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9106.json
@@ -0,0 +1 @@
+{"TRELEGY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9107.json
new file mode 100644
index 00000000000..b3c5528a5a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9107.json
@@ -0,0 +1 @@
+{"ALIMTA": 3.4355198825332045, "ARAVA": 0.2040451787565401, "BUPRENORPHINE": 2.100574646741852, "CABOMETYX": 4.065562228898975, "CLOPIDOGREL": 1.1709072950596997, "COMIRNATY": 0.6153889730717187, "ELIQUIS": 1.366551042616858, "EMPAGLIFLOZIN": 22.54036167742105, "ICLUSIG": 6.444370132216057, "KALETRA": 4.928891887840357, "LAMIVUDINE": 9.199746292940432, "NEXAVAR": 1.122104618397474, "NOVOSEVEN": 55.96816978497376, "OPTIMARK": 3.960055522563656, "PEGASYS": 0.8975272067213388, "PEMETREXED": 11.482248470918138, "PLAVIX": 1.1592719710896973, "ROACTEMRA": 7.700568925744635, "SPIKEVAX": 0.3031224479688582, "TASIGNA": 10.610451265862512, "TOZINAMERAN": 0.4182315401457858, "VAXZEVRIA": 0.6054623739482495, "null": 1.3135845700443476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9108.json
new file mode 100644
index 00000000000..037fe6a5e83
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9108.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 13.408992819907525, "BLINATUMOMAB": 363.0720385040647, "COMIRNATY": 0.3330339397265374, "DABRAFENIB": 45.268081504696575, "NORVIR": 36.550546887176736, "PEGASYS": 2.9221716322032134, "THALIDOMIDE": 68.0896975870547, "VAXZEVRIA": 0.2315949231733255, "null": 0.93749460745842}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9109.json
new file mode 100644
index 00000000000..66441a1e9e9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9109.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1863233623252911, "FENTANYL": 8.875283081735578, "LEVOFLOXACIN": 10.265902276962256, "null": 1.588008849299463}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/911.json
index 0769221caac..6b819417772 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/911.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/911.json
@@ -1 +1 @@
-{"null": 7.989991806006669}
\ No newline at end of file
+{"ALDARA": 532.9627777471007, "null": 3.246420143999724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9110.json
new file mode 100644
index 00000000000..41367ff1be4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9110.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.186191775351876, "SPIKEVAX": 0.8104872506524198, "VAXZEVRIA": 0.560196570402132, "null": 0.7049709398530265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9111.json
new file mode 100644
index 00000000000..ab33c0d6f71
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9111.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6798925160898103, "null": 0.907624958157944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9112.json
new file mode 100644
index 00000000000..2c7e5554c19
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9112.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.527825960790225, "null": 0.4309090647495694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9113.json
new file mode 100644
index 00000000000..b5fffaf4307
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9113.json
@@ -0,0 +1 @@
+{"ENTYVIO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9114.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9114.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9115.json
new file mode 100644
index 00000000000..7f0b4446fe0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9115.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.9581872260597012, "GARDASIL": 8.092680980914258, "SPIKEVAX": 1.108230356806107, "null": 0.7768972258722477}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9116.json
new file mode 100644
index 00000000000..faf8583ff69
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9116.json
@@ -0,0 +1 @@
+{"LOPINAVIR": 466.2048133717102, "null": 0.5563632974768191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9117.json
new file mode 100644
index 00000000000..cbd4f8052f9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9117.json
@@ -0,0 +1 @@
+{"AMINOSALICYLIC": 14.16113331860664, "COMIRNATY": 0.2375492738208276, "CYMBALTA": 2.7840353685044845, "DEXAMETHASONE": 6.041683860535803, "KALETRA": 10.27184626560527, "PEGASYS": 2.0087261054667325, "TELMISARTAN": 69.99693825383892, "VAXZEVRIA": 0.1766456100732855, "null": 1.044458610815335}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9118.json
new file mode 100644
index 00000000000..ed7e3a526f7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9118.json
@@ -0,0 +1 @@
+{"ABRAXANE": 14.671557522902848, "ADCETRIS": 28.956403504266547, "ALIMTA": 2.454926443280172, "AMINOSALICYLIC": 2.826441540427532, "ARAVA": 0.2250676602250336, "ASPARAGINASE": 3.4635638025119397, "ATAZANAVIR": 5.236181018429772, "AUBAGIO": 1.6688589057487293, "AVASTIN": 10.552654803100868, "BEVACIZUMAB": 9.741974754649698, "BLINATUMOMAB": 33.80432070279049, "BORTEZOMIB": 26.60243216122796, "CAPECITABINE": 7.453725649784548, "CICLOSPORIN": 1.051592601107432, "COMIRNATY": 0.2439733500390925, "CYMBALTA": 0.3983986903077041, "CYTARABINE": 6.633860156241059, "DABRAFENIB": 10.448255366274385, "DARUNAVIR": 10.513837397476994, "DARZALEX": 5.617823365857957, "DEXAMETHASONE": 4.812270639406506, "DOCETAXEL": 4.2701728296195975, "ERBITUX": 16.333154170616254, "EVEROLIMUS": 16.274647361266226, "HALAVEN": 11.64383512958491, "HERCEPTIN": 3.854672781068957, "IRINOTECAN": 24.730800273427302, "KEYTRUDA": 1.8102872661328095, "NEXAVAR": 0.8019458177019932, "NORVIR": 7.426022793299137, "OPDIVO": 4.0890285886855136, "PACLITAXEL": 12.865449832205602, "PANITUMUMAB": 38.809223758920666, "PEGASYS": 1.1084111607696563, "SPIKEVAX": 0.1270946985865298, "TELMISARTAN": 15.417019349574757, "THALIDOMIDE": 86.03693107542922, "TOZINAMERAN": 0.3483297351029962, "VAXZEVRIA": 0.2083791108111848, "VELCADE": 29.22554974512547, "null": 1.431065287615561}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9119.json
new file mode 100644
index 00000000000..9518eaa2b44
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9119.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 1.3138754779019717, "ABATACEPT": 4.306006403966413, "ABILIFY": 0.2226829224826942, "ADALIMUMAB": 1.182219731652019, "ADCIRCA": 3.807379056808041, "ADEMPAS": 1.750514923716723, "ADENURIC": 0.635767184157192, "ADVATE": 1.1915643315273952, "AERIUS": 0.3563373485788118, "AFINITOR": 0.9732877468615384, "AIMOVIG": 0.3905455454670463, "ALBIGLUTIDE": 6.617030366243652, "ALEMTUZUMAB": 0.2023904353731456, "ALIMTA": 0.3072264143033004, "ALISKIREN": 1.803015270758592, "AMBRISENTAN": 2.21963515297341, "AMINOSALICYLIC": 0.147662838647139, "ANAKINRA": 0.9027561285500072, "ANORO": 0.1799521270500635, "APIDRA": 0.6300308441715811, "APIXABAN": 0.5861214853255867, "APREMILAST": 3.2941311668734694, "APREPITANT": 0.3975103050970509, "APROVEL": 0.2930367848956175, "ARANESP": 0.4569011236972032, "ARAVA": 2.9336385852086497, "ARIPIPRAZOLE": 0.0756440063970763, "ATRIPLA": 0.0546853602614506, "AUBAGIO": 0.7409150385393845, "AVAMYS": 0.4270327220113941, "AVANDAMET": 0.6329194386584449, "AVANDIA": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/912.json
index 25f68494b01..5d23ff9dd1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/912.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/912.json
@@ -1 +1 @@
-{"null": 4.1423793880704975}
\ No newline at end of file
+{"ALDARA": 64.92981737708975, "EVRA": 76.84951553435127, "QUTENZA": 82.97038620744593, "SIMPONI": 4.764251202101868, "null": 10.266035606995644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9120.json
new file mode 100644
index 00000000000..536c3fcc489
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9120.json
@@ -0,0 +1 @@
+{"APIXABAN": 0.6554470890848157, "ARAVA": 0.3099257167974245, "AVANDAMET": 5.234960823364357, "AVANDIA": 6.756682927408639, "BOSUTINIB": 16.766662244673572, "BYETTA": 1.8338809799024065, "COMIRNATY": 1.474529241531532, "ELIQUIS": 0.9027061496074454, "ENBREL": 0.5315306060399451, "ENTRESTO": 0.7530017604039755, "FORSTEO": 0.6024539815973864, "GARDASIL": 3.770380738095266, "HUMALOG": 2.0244173817163587, "ICLUSIG": 4.207833105397713, "JANUMET": 1.460582692041782, "JANUVIA": 2.458773352660824, "JARDIANCE": 1.3965672296476244, "LANTUS": 1.0281604032607086, "NILOTINIB": 22.549931040880217, "OPTIMARK": 1.4501017490113175, "PLAVIX": 0.7331874703623575, "SHINGRIX": 3.632201996482195, "SPIKEVAX": 0.885186703411605, "SPRYCEL": 1.3168225546253247, "TASIGNA": 25.990292032355544, "TOZINAMERAN": 0.1630652440174238, "TWINRIX": 5.822038149731333, "VAXZEVRIA": 1.7942759097128065, "VIAGRA": 1.5598722302096528, "ZOSTAVAX": 3.3146273388136365, "ZYPREXA": 0.745868685657503, "null": 0.7935326239700108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9121.json
new file mode 100644
index 00000000000..b88e5b9c08b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9121.json
@@ -0,0 +1 @@
+{"ABATACEPT": 6.978953287063144, "ADALIMUMAB": 22.15785426446209, "APREMILAST": 21.312116555646824, "ARAVA": 1.1536691359324196, "BYETTA": 2.447988307281232, "CIMZIA": 2.9083587511426905, "COMIRNATY": 0.7371706357081381, "COSENTYX": 5.793109705229326, "ELIQUIS": 1.94552378290562, "HYDROCORTISONE": 4.440242135666392, "LANTUS": 0.5852781239733255, "SPIKEVAX": 0.2535061465870473, "TOZINAMERAN": 0.3792525749471747, "VAXZEVRIA": 0.5298727001809361, "ZOSTAVAX": 3.586291832250971, "ZYPREXA": 2.631285683951333, "null": 0.4360418068295739}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9122.json
new file mode 100644
index 00000000000..a107f8858a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9122.json
@@ -0,0 +1 @@
+{"null": 1.154974243957014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9123.json
new file mode 100644
index 00000000000..bb6b15e329b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9123.json
@@ -0,0 +1 @@
+{"null": 2.730503190934328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9124.json
new file mode 100644
index 00000000000..3f9d9cd048c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9124.json
@@ -0,0 +1 @@
+{"RIBOCICLIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9125.json
new file mode 100644
index 00000000000..463fc11a81d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9125.json
@@ -0,0 +1 @@
+{"null": 0.5959097619204412}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9126.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9126.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9127.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9127.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9128.json
new file mode 100644
index 00000000000..cdff8f7ced1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9128.json
@@ -0,0 +1 @@
+{"CIMZIA": 10.017706463459527, "JARDIANCE": 9.232228934998696, "null": 0.5019098837847187}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9129.json
new file mode 100644
index 00000000000..57a24b12268
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9129.json
@@ -0,0 +1 @@
+{"null": 0.5253215492245955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/913.json
index 976eface428..ef661f7c878 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/913.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/913.json
@@ -1 +1 @@
-{"null": 2.7324561440655404}
\ No newline at end of file
+{"VAXZEVRIA": 0.3284327372975138, "null": 7.203343637377486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9130.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9130.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9131.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9131.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9132.json
new file mode 100644
index 00000000000..4bbb80b9d14
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9132.json
@@ -0,0 +1 @@
+{"null": 23.323337520649257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9133.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9133.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9134.json
new file mode 100644
index 00000000000..2865d04a9a2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9134.json
@@ -0,0 +1 @@
+{"ARANESP": 88.77303311505199, "null": 0.646064254437105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9135.json
new file mode 100644
index 00000000000..afd567bb5ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9135.json
@@ -0,0 +1 @@
+{"null": 22.992946049789907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9136.json
new file mode 100644
index 00000000000..51f8d2fc3bb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9136.json
@@ -0,0 +1 @@
+{"AVASTIN": 52.517525052916696, "null": 0.937605483765232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9137.json
new file mode 100644
index 00000000000..f47f54ef190
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9137.json
@@ -0,0 +1 @@
+{"null": 7.574671030412715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9138.json
new file mode 100644
index 00000000000..a96a50dd56c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9138.json
@@ -0,0 +1 @@
+{"null": 1.3922402560496778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9139.json
new file mode 100644
index 00000000000..055333c65ab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9139.json
@@ -0,0 +1 @@
+{"null": 1.5474215671674476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/914.json
index ed66c850f02..51865c4a499 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/914.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/914.json
@@ -1 +1 @@
-{"null": 1.759771783674484}
\ No newline at end of file
+{"null": 41.03177721812367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9140.json
new file mode 100644
index 00000000000..e94e00ba1c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9140.json
@@ -0,0 +1 @@
+{"ARANESP": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9141.json
new file mode 100644
index 00000000000..8b5194a1f61
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9141.json
@@ -0,0 +1 @@
+{"LEMTRADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9142.json
new file mode 100644
index 00000000000..c950c15d3a7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9142.json
@@ -0,0 +1 @@
+{"RASILEZ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9143.json
new file mode 100644
index 00000000000..4f2377d5550
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9143.json
@@ -0,0 +1 @@
+{"ABACAVIR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9144.json
new file mode 100644
index 00000000000..59bd804b350
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9144.json
@@ -0,0 +1 @@
+{"CIMZIA": 13.942961654350846, "PEGINTRON": 20.86643233759957, "SIMPONI": 41.59698921073479, "null": 0.1473177965099242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9145.json
new file mode 100644
index 00000000000..6c4b5a68a20
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9145.json
@@ -0,0 +1 @@
+{"LONSURF": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9146.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9146.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9147.json
new file mode 100644
index 00000000000..73d39f4ce77
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9147.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.8989107581458357, "ALIMTA": 3.129826647901603, "ANIDULAFUNGIN": 33.843766951424854, "ARANESP": 4.3002807585614224, "ARIPIPRAZOLE": 1.7531258410464965, "ASPARAGINASE": 2.3044057099609327, "AVASTIN": 23.75170365490472, "AZATHIOPRINE": 1.8430487028090607, "BEDAQUILINE": 3.046480804019243, "BEVACIZUMAB": 3.866838655108787, "CABOMETYX": 1.5407862984763687, "CELLCEPT": 5.068658084155625, "CICLOSPORIN": 3.7921370246896826, "CIMZIA": 0.3786207402892131, "CLOPIDOGREL": 0.6670973646997848, "COMIRNATY": 0.1069818485234363, "COSENTYX": 0.5132234684257533, "DEXAMETHASONE": 2.483874832177575, "DOCETAXEL": 2.213287758370078, "ECULIZUMAB": 41.09252560238984, "EMTRICITABINE": 4.682494025458942, "ENBREL": 0.6578466181385192, "FORSTEO": 1.24256319477173, "HUMIRA": 1.1876835476845773, "INCIVO": 1.857309709975416, "IPILIMUMAB": 2.2190722713139697, "IRESSA": 4.753691269167062, "IRINOTECAN": 3.40998473978924, "ISENTRESS": 3.8194366330449774, "JAKAVI": 1.3940643460872189, "JANUVIA": 0.7621031413546708, "KALETRA": 1.370167890338881, "KEYTRUDA": 1.990055179370499, "LANTUS": 0.3803141134101764, "LENVIMA": 2.652979241113815, "MEKINIST": 1.1673565157750605, "METHOTREXATE": 1.6935369091922994, "MYCOPHENOLATE": 3.214422121006701, "NEXAVAR": 2.4924478670896604, "OLANZAPINE": 1.1443220492528825, "OPDIVO": 2.603082735384791, "PEGASYS": 0.9905883361222771, "PEGINTRON": 2.3135606293766737, "PEMBROLIZUMAB": 1.8377800186453916, "REMICADE": 4.382928698491725, "ROACTEMRA": 18.309373716437896, "SIMPONI": 0.6433215391590771, "SOLIRIS": 3.4172283699725168, "SPIKEVAX": 0.0273758844402024, "STELARA": 1.4583481470847477, "STIVARGA": 4.713961807887195, "SUTENT": 2.1670159327057403, "TACROLIMUS": 9.178477286389231, "TORISEL": 5.153673278473041, "TRACLEER": 0.9483091353446144, "TRULICITY": 1.247813411931925, "VAXZEVRIA": 0.0451116906547347, "VOTRIENT": 1.0027131880958766, "XELJANZ": 0.7732678871590742, "YERVOY": 6.7155303973396485, "ZYPREXA": 0.6077971629721617, "null": 1.8316947979820608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9148.json
new file mode 100644
index 00000000000..9eebfd5f1be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9148.json
@@ -0,0 +1 @@
+{"ARANESP": 9.571402807340782, "CICLOSPORIN": 2.9546651205485226, "PEGASYS": 3.8031219938512897, "PEGINTRON": 11.375328909316169, "SOLIRIS": 7.496208646636274, "null": 1.9714199609073964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9149.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9149.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/915.json
index ae30face159..9b37ec6a6ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/915.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/915.json
@@ -1 +1 @@
-{"JANUMET": 45.94811212194794, "JANUVIA": 38.42672633533208, "TRACLEER": 70.25801614930803}
\ No newline at end of file
+{"null": 7.187642545837001}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9150.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9150.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9151.json
new file mode 100644
index 00000000000..9a655a3299d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9151.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7904911139277513, "COSENTYX": 6.582509182726184, "null": 0.9616286443792094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9152.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9152.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9153.json
new file mode 100644
index 00000000000..01b4981d75e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9153.json
@@ -0,0 +1 @@
+{"null": 3.061033588098457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9154.json
new file mode 100644
index 00000000000..b823c774e84
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9154.json
@@ -0,0 +1 @@
+{"null": 1.3268530254153246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9155.json
new file mode 100644
index 00000000000..f7df8eff86d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9155.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.5176849316338226, "SPIKEVAX": 1.0737865200478605, "TOZINAMERAN": 9.693276230722391, "VAXZEVRIA": 0.8489511737593373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9156.json
new file mode 100644
index 00000000000..926a668ffac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9156.json
@@ -0,0 +1 @@
+{"null": 0.9941356751398872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9157.json
new file mode 100644
index 00000000000..71e46c19d87
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9157.json
@@ -0,0 +1 @@
+{"ATRIPLA": 0.4453885242690724, "AUBAGIO": 8.338161126822724, "BOSULIF": 11.528472180872493, "CLOPIDOGREL": 1.884400723350272, "COMIRNATY": 0.4452415070821954, "DEXAMETHASONE": 2.7418710968766957, "ELIQUIS": 1.0289446275036775, "FAMPYRA": 8.642878611179482, "GARDASIL": 1.2338174237761756, "HUMALOG": 1.572664322733942, "KEPPRA": 1.4237666259436117, "LYRICA": 3.036231005527762, "OCRELIZUMAB": 7.332546810017771, "OPTIMARK": 3.9354419225954103, "PEGASYS": 2.3608292066645986, "PEGINTRON": 4.7922438923996005, "SPIKEVAX": 0.3059622725785298, "TOZINAMERAN": 1.3407902053252758, "VAXZEVRIA": 0.2781134005721676, "ZOSTAVAX": 2.9670479077770184, "null": 1.030793617418294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9158.json
new file mode 100644
index 00000000000..ddd319d85cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9158.json
@@ -0,0 +1 @@
+{"LEVODOPA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9159.json
new file mode 100644
index 00000000000..223dfa1bb1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9159.json
@@ -0,0 +1 @@
+{"ABILIFY": 4.395464191973228, "ARIPIPRAZOLE": 24.16153176144859, "BIKTARVY": 6.87463343559486, "BRINTELLIX": 2.835190480335049, "BUPRENORPHINE": 4.587230631108052, "CHAMPIX": 4.484071041794281, "DULOXETINE": 10.915227383996749, "ENTACAPONE": 28.811704935331065, "FYCOMPA": 17.46253025377572, "KEPPRA": 2.988971871862948, "LATUDA": 11.349998166176958, "LEVETIRACETAM": 2.4905237008043377, "LURASIDONE": 86.42905429623825, "LYRICA": 3.3330717688085696, "OLANZAPINE": 19.831389101210128, "PANTOPRAZOLE": 12.132434602242313, "PEGASYS": 0.8939017675901354, "VFEND": 4.118966244746465, "ZYPREXA": 8.148108422900913, "null": 1.938787730631812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/916.json
index b3e5d101f2c..1587b023532 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/916.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/916.json
@@ -1 +1 @@
-{"KALETRA": 32.78124675914216, "null": 1.5991447176969125}
\ No newline at end of file
+{"ALDARA": 156.95737222410713, "null": 7.25501634966155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9160.json
new file mode 100644
index 00000000000..905053db8db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9160.json
@@ -0,0 +1 @@
+{"KEPPRA": 19.1788300514043, "null": 1.719766998457522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9161.json
new file mode 100644
index 00000000000..3b0ed86c868
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9161.json
@@ -0,0 +1 @@
+{"null": 1.7801097803014172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9162.json
new file mode 100644
index 00000000000..9b6ba5a470d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9162.json
@@ -0,0 +1 @@
+{"ABILIFY": 11.218819192979408, "BUPRENORPHINE": 13.702606485716736, "COMTAN": 78.08807940996124, "CYMBALTA": 3.63639061514326, "null": 1.389929920739942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9163.json
new file mode 100644
index 00000000000..b57b9bf03b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9163.json
@@ -0,0 +1 @@
+{"null": 3.981617965166241}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9164.json
new file mode 100644
index 00000000000..24e60349b59
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9164.json
@@ -0,0 +1 @@
+{"null": 2.822612585487926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9165.json
new file mode 100644
index 00000000000..9f5c37a38ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9165.json
@@ -0,0 +1 @@
+{"LURASIDONE": 4464.526009175805, "null": 1.0685011017336197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9166.json
new file mode 100644
index 00000000000..d28f3656163
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9166.json
@@ -0,0 +1 @@
+{"null": 4.676747362804496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9167.json
new file mode 100644
index 00000000000..815ff9b0eaf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9167.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.5275457955654077, "TOZINAMERAN": 4.606434254499339, "VAXZEVRIA": 3.957372253018416, "null": 0.211999879867628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9168.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9168.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9169.json
new file mode 100644
index 00000000000..153732d361a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9169.json
@@ -0,0 +1 @@
+{"ABILIFY": 12.03033426106392, "BUPRENORPHINE": 48.37616256134434, "FENTANYL": 12.144640636683445, "NUCALA": 38.66495147089283, "SUBOXONE": 8.72415631240863, "null": 3.4142823513692035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/917.json
index 427db242f9f..6f7e9d58119 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/917.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/917.json
@@ -1 +1 @@
-{"OPSUMIT": 27.363848627874397, "null": 1.0467952876946884}
\ No newline at end of file
+{"ALDARA": 67.11979005014729, "AMELUZ": 527.8871000544974, "BETAFERON": 5.274827850391704, "BUPRENORPHINE": 4.781033774332136, "COMIRNATY": 0.509259925836232, "EVRA": 41.56481712396383, "FORSTEO": 0.6399552948694595, "IMIQUIMOD": 46.69466124977386, "KENTERA": 167.2531812692705, "MIRVASO": 73.88376577264752, "NEULASTA": 1.180424269759218, "NIMENRIX": 1.7096994476405531, "OPSUMIT": 0.3829937858316753, "PLEGRIDY": 1.4477949147658242, "QUTENZA": 225.29606416842825, "ROACTEMRA": 1.1933321371023553, "SHINGRIX": 1.0848042238809965, "SIMPONI": 0.5521495622640619, "SPIKEVAX": 1.6735128352749526, "VAXZEVRIA": 1.087946127807997, "ZYCLARA": 30.13450349102564, "null": 3.1722809506438114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9170.json
new file mode 100644
index 00000000000..637e088faf1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9170.json
@@ -0,0 +1 @@
+{"ABILIFY": 36.74182942947217, "ARIPIPRAZOLE": 5.00734670405018, "ATRIPLA": 0.2364468629348522, "BRINTELLIX": 1.1228824061297762, "CHAMPIX": 20.01295082233087, "COMIRNATY": 0.1374592856599235, "CYMBALTA": 2.1312430686808117, "ELIQUIS": 0.3276980023625964, "FYCOMPA": 13.786134240113562, "GARDASIL": 2.1388317055107806, "INFANRIX": 8.903119479406502, "KAFTRIO": 4.698837648176494, "KEPPRA": 9.359790969775522, "LANTUS": 0.373239444805558, "LATUDA": 2.784330587886993, "LEVETIRACETAM": 4.953128146583439, "MMRVAXPRO": 1.2625274038379313, "OLANZAPINE": 0.9342284600300418, "PEGASYS": 1.1448967503462324, "PEGINTRON": 0.8989493827057835, "PLAVIX": 0.5941790353283236, "RIBAVIRIN": 2.737295244151301, "SIFROL": 11.775302922678398, "SPIKEVAX": 0.0866725914602695, "TAMIFLU": 2.408148543568479, "TOZINAMERAN": 0.2736610065824782, "VAXZEVRIA": 0.0690150534331728, "ZYPREXA": 1.2436394825325965, "null": 2.2346275861059843}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9171.json
new file mode 100644
index 00000000000..0e29b367bd4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9171.json
@@ -0,0 +1 @@
+{"ABILIFY": 127.67347794842408, "BELIMUMAB": 3441.48211353264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9172.json
new file mode 100644
index 00000000000..daf49eccbcf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9172.json
@@ -0,0 +1 @@
+{"ABILIFY": 8.344420169633269, "AIMOVIG": 21.6509004308254, "ALISKIREN": 173.4037778316689, "CHAMPIX": 7.266990683499798, "COMIRNATY": 0.0571477289324647, "CYMBALTA": 0.8788555590959616, "ESOMEPRAZOLE": 16.453934643661885, "IVABRADINE": 98.99076893959575, "KALETRA": 6.244291477941367, "KEPPRA": 6.40954245457839, "LEVETIRACETAM": 5.675585405055448, "OLANZAPINE": 3.24452637666751, "PEGASYS": 1.5496441163953698, "ZYPREXA": 3.182268678831566, "null": 2.1407087341372275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9173.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9173.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9174.json
new file mode 100644
index 00000000000..bd18e5648d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9174.json
@@ -0,0 +1 @@
+{"null": 4.76949282430012}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9175.json
new file mode 100644
index 00000000000..77e50153094
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9175.json
@@ -0,0 +1 @@
+{"CIMZIA": 5.73848130530222, "COMIRNATY": 0.2015091424672453, "STELARA": 9.813323581256924, "null": 1.4907157840646728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9176.json
new file mode 100644
index 00000000000..522f03dce92
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9176.json
@@ -0,0 +1 @@
+{"AIMOVIG": 0.296046810221933, "ALEMTUZUMAB": 1.4106102913018814, "ALIMTA": 1.2217676513332063, "APIXABAN": 0.2833646186137322, "ARAVA": 0.0872314298628269, "AUBAGIO": 0.3159300310504221, "AVASTIN": 0.4624527246970589, "AZATHIOPRINE": 0.720282734320106, "BETMIGA": 2.477451035451456, "BEXSERO": 4.378631320491999, "BRIDION": 1.304804465932939, "BRILIQUE": 6.172045875074043, "BRINTELLIX": 0.4655361864491895, "BRUKINSA": 8.51423323903242, "CELLCEPT": 0.5197476371806119, "CHAMPIX": 0.4744969831115628, "CICLOSPORIN": 0.6636408924168068, "CLOPIDOGREL": 3.815201351644321, "COMIRNATY": 1.288780339280826, "CYMBALTA": 0.2521567003261362, "CYTARABINE": 1.006796390255595, "ELIQUIS": 2.157762724524373, "ENBREL": 0.4574986077886131, "ENOXAPARIN": 4.770014998758479, "ENTRESTO": 0.2538766983446195, "EXFORGE": 0.5068602479126088, "EXJADE": 1.3381529821441656, "GARDASIL": 1.3005935288454615, "HUMAN": 1.4336305489060168, "HUMIRA": 0.3307105712222208, "IBRANCE": 0.1532992881473407, "IBUPROFEN": 0.5864482449070232, "INFANRIX": 4.410442287899118, "INTEGRILIN": 5.555594037234224, "JAKAVI": 0.4869599425536208, "KEPPRA": 0.5792458752064645, "LEMTRADA": 6.095128185955944, "LEVETIRACETAM": 0.5884158599913449, "LEVOFLOXACIN": 0.7286120520872074, "LIXIANA": 3.082395822676621, "MENVEO": 3.684071865941208, "MMRVAXPRO": 5.56932217385685, "MODERNA": 0.7685005781035471, "NEXAVAR": 0.3972221713835402, "NIMENRIX": 3.654132230849064, "NOVONORM": 2.9587553744478896, "NPLATE": 13.91609803673088, "OLANZAPINE": 0.2244017018349797, "OPTIMARK": 0.5534242211564325, "PANTOPRAZOLE": 2.1811576107846555, "PEGASYS": 0.2715608882547129, "PEGINTRON": 0.4971562911540352, "PEMBROLIZUMAB": 1.0667309879261613, "PLAVIX": 2.707303952900012, "PREVENAR": 9.995375776545409, "RINVOQ": 0.5074566447702262, "ROACTEMRA": 0.904744759454306, "ROTATEQ": 2.2613576401587507, "SHINGRIX": 0.575603110869486, "SOLIRIS": 0.9329448020236004, "SPIKEVAX": 0.6340245822462169, "STELARA": 0.1788833888402928, "STIVARGA": 0.3921695648933971, "SUTENT": 1.0444490099793096, "SYNAGIS": 1.67305795506847, "TAMIFLU": 1.8873022333981933, "TASIGNA": 0.5868611573795923, "TEMODAL": 4.815179466232132, "TEMOZOLOMIDE": 3.127501591806748, "TOZINAMERAN": 0.6603602524978879, "TWINRIX": 2.077163099721941, "VAXZEVRIA": 2.331969260360058, "VIMPAT": 0.935695411262314, "VOTRIENT": 0.3918707911490718, "XARELTO": 1.5932245883826373, "XOLAIR": 0.3697329548651897, "ZOSTAVAX": 0.22536041104878, "ZYPREXA": 0.4062392114068119, "null": 1.0100979690342906}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9177.json
new file mode 100644
index 00000000000..b62ec5dc90b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9177.json
@@ -0,0 +1 @@
+{"ATAZANAVIR": 4.9772506643692775, "BOTULINUM": 5.875485024331357, "BRIVARACETAM": 23.244622915869808, "BRIVIACT": 26.51918637846004, "CANNABIDIOL": 11.787846729550232, "CELSENTRI": 38.55345919083141, "CHAMPIX": 2.298467437469513, "COMIRNATY": 0.2454281412886661, "CYMBALTA": 0.5318898069098411, "DESLORATADINE": 18.491660505131037, "FYCOMPA": 9.475416310747857, "GARDASIL": 2.7736409903945827, "KEPPRA": 33.75872527741348, "LACOSAMIDE": 23.317908781810512, "LEVETIRACETAM": 22.29898042537243, "MMRVAXPRO": 1.8729285324702656, "OLANZAPINE": 1.808914067505132, "PEGASYS": 0.2783624163799301, "SPIKEVAX": 0.1301884895125617, "TOZINAMERAN": 0.4816239495008785, "VAXZEVRIA": 0.2240388361219581, "VIMPAT": 26.92714130644329, "XTANDI": 0.9033696557855754, "ZYPREXA": 1.7165260925780097, "null": 2.1025037349778737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9178.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9178.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9179.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9179.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/918.json
index 2eaa598f27b..9a785486feb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/918.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/918.json
@@ -1 +1 @@
-{"null": 1.53567740245871}
\ No newline at end of file
+{"AMELUZ": 1032.0127431283329, "null": 16.482719884173395}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9180.json
new file mode 100644
index 00000000000..58b0fdff47d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9180.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2091822639915144, "VIAGRA": 62.175907366819686, "null": 2.425482684865147}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9181.json
new file mode 100644
index 00000000000..26aad4061d2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9181.json
@@ -0,0 +1 @@
+{"SUTENT": 2.604442496067667, "null": 2.1581683252079142}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9182.json
new file mode 100644
index 00000000000..87b490a5593
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9182.json
@@ -0,0 +1 @@
+{"null": 1.56340807827671}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9183.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9183.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9184.json
new file mode 100644
index 00000000000..119d8c63f15
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9184.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 35.53403974284719, "null": 0.2255961473406682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9185.json
new file mode 100644
index 00000000000..cb30bce39d1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9185.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 205.86189425043077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9186.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9186.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9187.json
new file mode 100644
index 00000000000..3d10e40cbce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9187.json
@@ -0,0 +1 @@
+{"null": 1.006633644640497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9188.json
new file mode 100644
index 00000000000..c595565a0b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9188.json
@@ -0,0 +1 @@
+{"null": 4.019963153301754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9189.json
new file mode 100644
index 00000000000..f33ddac68dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9189.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7036307360405232, "CYMBALTA": 7.860297724552379, "VAXZEVRIA": 1.3882443104783329, "null": 0.8265660265104664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/919.json
index 15836c7d4d5..497c1b509aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/919.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/919.json
@@ -1 +1 @@
-{"null": 3.0938723142390154}
\ No newline at end of file
+{"null": 11.127605575167744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9190.json
new file mode 100644
index 00000000000..b3ddc21a3e3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9190.json
@@ -0,0 +1 @@
+{"null": 10.502626512889767}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9191.json
new file mode 100644
index 00000000000..3948ec567c9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9191.json
@@ -0,0 +1 @@
+{"null": 1.0442696383133216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9192.json
new file mode 100644
index 00000000000..4ae9a87b939
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9192.json
@@ -0,0 +1 @@
+{"null": 0.7662043357759128}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9193.json
new file mode 100644
index 00000000000..731a739207a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9193.json
@@ -0,0 +1 @@
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9194.json
new file mode 100644
index 00000000000..6dede4261ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9194.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9195.json
new file mode 100644
index 00000000000..14f095b2144
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9195.json
@@ -0,0 +1 @@
+{"AERIUS": 25.158272307803493, "CLOPIDOGREL": 2.330383961314307, "COMIRNATY": 0.1627485810188586, "IBRANCE": 3.82229717814982, "LANTUS": 1.4493083918281526, "PEGASYS": 2.8197355795100525, "RELVAR": 17.440806358920618, "SUTENT": 0.9515379198692788, "TOZINAMERAN": 1.1529965849852328, "XELJANZ": 3.3043807760556003, "XOLAIR": 4.549457264915034, "null": 1.7703835070455518}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9196.json
new file mode 100644
index 00000000000..5e92ba3428a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9196.json
@@ -0,0 +1 @@
+{"null": 0.9978144146412992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9197.json
new file mode 100644
index 00000000000..9da552d92e0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9197.json
@@ -0,0 +1 @@
+{"null": 1.5045972803916627}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9198.json
new file mode 100644
index 00000000000..2a3a5708c46
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9198.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 1.785023956357153, "COMIRNATY": 0.4818042208715455, "DEXAMETHASONE": 1.8880345486049976, "GARDASIL": 2.415028433920557, "KEPPRA": 1.3782929624474092, "MMRVAXPRO": 19.45851738799934, "NIMENRIX": 7.893943250534347, "NUCALA": 4.98988916409075, "ROTATEQ": 13.229747586236387, "SPIKEVAX": 0.3892661051975495, "TOZINAMERAN": 0.7179458810641929, "VAXZEVRIA": 0.2205305805484899, "null": 2.130972476728882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9199.json
new file mode 100644
index 00000000000..aca2a3eccd0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9199.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 36.45747748358459, "null": 2.1574506275571173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/92.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/92.json
index e21cb7522a7..0d2ac78bc1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/92.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/92.json
@@ -1 +1 @@
-{"null": 1.6524088228168026}
\ No newline at end of file
+{"null": 1.80462367809423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/920.json
index 36d359c3245..b9f9dd82b1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/920.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/920.json
@@ -1 +1 @@
-{"null": 1.2750659248573155}
\ No newline at end of file
+{"null": 4.007718127168797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9200.json
new file mode 100644
index 00000000000..8ff0b854ba7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9200.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 5.423366477627594, "COMIRNATY": 0.101579289311069, "ELIQUIS": 13.00832080251441, "PEGASYS": 1.928213345591658, "PLAVIX": 4.9139193713642, "SPIKEVAX": 0.221098256487065, "SUTENT": 1.4796121612600066, "null": 1.1686412252189595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9201.json
new file mode 100644
index 00000000000..e993e2dabbb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9201.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.7845222854005145, "FENTANYL": 10.433552350822543, "SPIKEVAX": 0.4935910392937844, "TOZINAMERAN": 3.4974355688067407, "VAXZEVRIA": 0.8405269563626121, "null": 1.318680702589371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9202.json
new file mode 100644
index 00000000000..03a5cdf2a29
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9202.json
@@ -0,0 +1 @@
+{"AVAMYS": 8.518412200648203, "BENLYSTA": 15.603543282020508, "COMIRNATY": 0.7293177843235095, "SPIKEVAX": 0.3496574799386456, "SUTENT": 2.2866218367043203, "TOZINAMERAN": 1.1627179655833548, "VAXZEVRIA": 0.1283791084513054, "null": 1.0506958507076165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9203.json
new file mode 100644
index 00000000000..ed689e9cac2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9203.json
@@ -0,0 +1 @@
+{"null": 4.806045512290792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9204.json
new file mode 100644
index 00000000000..f74386f6b75
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9204.json
@@ -0,0 +1 @@
+{"null": 1.3419956826253077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9205.json
new file mode 100644
index 00000000000..f4f039e6cd7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9205.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4008673848777639, "TOZINAMERAN": 3.321845601169696, "null": 0.8029654089497841}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9206.json
new file mode 100644
index 00000000000..f98727b5f2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9206.json
@@ -0,0 +1 @@
+{"null": 0.6150315419721749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9207.json
new file mode 100644
index 00000000000..37ec889456b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9207.json
@@ -0,0 +1 @@
+{"ADCIRCA": 5.8371633722833005, "APIDRA": 1.3524676214027351, "ARAVA": 0.7632665469212964, "BRIDION": 6.426404059869157, "CHAMPIX": 1.1739934383973578, "CIMZIA": 0.3871026295353588, "COMIRNATY": 0.6535665060631781, "COSENTYX": 0.7279315444864874, "ENBREL": 6.016188791196708, "EXFORGE": 1.4832821794798228, "FENTANYL": 0.6512840813681618, "GARDASIL": 1.140609786095211, "LEVOFLOXACIN": 1.141321482886135, "MICARDIS": 5.951735112876463, "OMALIZUMAB": 1.0856493648496357, "PEGASYS": 0.2731333650694892, "RASILEZ": 4.069912583406109, "SPIKEVAX": 0.3369182062073618, "TOZINAMERAN": 0.4902416969889293, "VAXZEVRIA": 0.2001131213520715, "XOLAIR": 2.791571589983282, "null": 3.954159520167317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9208.json
new file mode 100644
index 00000000000..117b332867c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9208.json
@@ -0,0 +1 @@
+{"null": 2.1482279923668317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9209.json
new file mode 100644
index 00000000000..d588e9fe8b1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9209.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.229071432327944, "FENTANYL": 5.062464222496529, "OMALIZUMAB": 3.105491409213105, "SPIKEVAX": 0.5618622277623851, "TOZINAMERAN": 2.3445977708030337, "VAXZEVRIA": 0.4738112534897193, "null": 1.7265734933471812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/921.json
index 65f3b5a0084..e857b4e7567 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/921.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/921.json
@@ -1 +1 @@
-{"JANUVIA": 230.84991083060143}
\ No newline at end of file
+{"COMIRNATY": 0.4730933259383872, "VAXZEVRIA": 2.098759434822448, "null": 1.0984862021146105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9210.json
new file mode 100644
index 00000000000..731a739207a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9210.json
@@ -0,0 +1 @@
+{"COSENTYX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9211.json
new file mode 100644
index 00000000000..7b5e68536c4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9211.json
@@ -0,0 +1 @@
+{"EPCLUSA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9212.json
new file mode 100644
index 00000000000..72b4bc642e8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9212.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.897983911580884, "null": 0.7945367150999303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9213.json
new file mode 100644
index 00000000000..cfb5bd96c9b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9213.json
@@ -0,0 +1 @@
+{"AERIUS": 1.4500870323258788, "AIMOVIG": 0.4784943915945349, "APIDRA": 0.4485544472964518, "ARAVA": 0.0421111219023789, "BENLYSTA": 0.463514155704047, "BUPRENORPHINE": 0.8214249026379364, "BYDUREON": 1.2003692471219876, "BYETTA": 0.62971145803903, "CHAMPIX": 2.0559874966711877, "CIMZIA": 0.4603053537400078, "CLOPIDOGREL": 0.1703501786217949, "COMIRNATY": 1.0668194583799944, "COSENTYX": 1.327385033690698, "CYMBALTA": 0.3968194671453282, "DEXAMETHASONE": 0.4045975857130682, "ELIQUIS": 0.3082215796786927, "ENBREL": 0.4440978774299794, "ENTRESTO": 1.5834914956447323, "ENTYVIO": 0.5522118434984095, "EXFORGE": 0.9670447073643712, "EXJADE": 0.5842360983411278, "FASENRA": 1.8766650216873608, "FASLODEX": 0.5267212323655377, "FORSTEO": 0.4388569211011724, "GARDASIL": 0.6563094984759226, "HIZENTRA": 2.2989709435581696, "HUMALOG": 0.3758666129267638, "HUMIRA": 0.4505072199550636, "IBRANCE": 0.2772099353168082, "IBUPROFEN": 0.4751098547398257, "INSULIN": 0.6477395260395403, "JANUVIA": 0.568398669172506, "JARDIANCE": 0.3702982050166348, "KEPPRA": 0.3122098687112327, "KEYTRUDA": 0.1140311319139085, "LANTUS": 0.4380024210206757, "LATUDA": 1.8859694744591613, "LEFLUNOMIDE": 2.420809110390329, "LEVEMIR": 0.6323373879093697, "LEVOFLOXACIN": 0.410049181928758, "LYRICA": 0.4640001836806191, "MENVEO": 2.147651021907916, "MEPOLIZUMAB": 0.3635105672008646, "MICARDIS": 0.878810577220849, "NEULASTA": 1.8862111285426904, "NEXAVAR": 0.3855880650047462, "NUCALA": 0.4059525922448813, "OMALIZUMAB": 1.3512340649961003, "PANTOPRAZOLE": 0.8530779172469388, "PEGASYS": 0.5655657303296445, "PEGINTRON": 0.6107107352131065, "PLAVIX": 0.9093305773416288, "PRIVIGEN": 1.835982215550448, "RASILEZ": 1.5286652363379034, "REVATIO": 1.1591738031855272, "RUCONEST": 134.7075176265005, "SHINGRIX": 0.7227352220529729, "SIMPONI": 0.4907491075214669, "SOLIRIS": 0.3605486622048724, "SPIKEVAX": 0.8581088430502636, "STELARA": 0.4821445541651693, "SUBOXONE": 4.073687752251192, "SUTENT": 0.2506084363217594, "TAMIFLU": 1.3814128797660228, "TOVIAZ": 2.2650142803064, "TOZINAMERAN": 2.496075794720312, "TRELEGY": 1.500229117948153, "TRULICITY": 0.5296991986189902, "VAXZEVRIA": 0.585618781545188, "XELJANZ": 0.4955818597419994, "XOLAIR": 5.751740422515013, "XTANDI": 0.3534062993728019, "ZOSTAVAX": 0.2903645328698117, "null": 1.796499369185642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9214.json
new file mode 100644
index 00000000000..55ff2a5cf43
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9214.json
@@ -0,0 +1 @@
+{"PEGASYS": 5.874985072507446, "PLAVIX": 5.653326561836133, "RITUXIMAB": 12.81516869417161, "SUTENT": 3.232553209977329, "TOZINAMERAN": 1.8462797110068827, "VAXZEVRIA": 0.3782196776474484, "null": 0.6835181576425995}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9215.json
new file mode 100644
index 00000000000..0d429e1353b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9215.json
@@ -0,0 +1 @@
+{"ACETYLSALICYLIC": 102.13676139474896, "AFINITOR": 0.5681932678872098, "ARAVA": 1.3336901019840046, "AVAMYS": 1.225722162688056, "BENLYSTA": 4.80104222973927, "CASPOFUNGIN": 6.453135242464469, "CHAMPIX": 0.6702059489404202, "CICLOSPORIN": 1.0171376785709163, "CIMZIA": 1.370620239121629, "COMBIVIR": 2.108673334253926, "COMIRNATY": 0.6262560093965934, "COSENTYX": 3.3496331853071872, "CYMBALTA": 0.2610795902633407, "ENBREL": 3.394320856624504, "ENTYVIO": 2.0146480372178823, "ETANERCEPT": 22.791669832868497, "EXJADE": 1.521880049976355, "FASENRA": 7.431989635152971, "FORSTEO": 0.641917750315147, "FULVESTRANT": 1.99346648266026, "GARDASIL": 3.816142607469242, "HALAVEN": 3.575939261741412, "HIZENTRA": 1.57415199072372, "HUMALOG": 0.5195946888991229, "HUMIRA": 0.922902462612571, "IBRANCE": 0.7604961899524054, "IBUPROFEN": 1.4010755835999646, "INCIVO": 1.4120483298452533, "JARDIANCE": 0.3726924400223882, "KEPPRA": 0.5731434751680552, "LANTUS": 0.268982917900368, "LEVOFLOXACIN": 0.5779803756079955, "MENVEO": 4.873705111979427, "MEPOLIZUMAB": 1.2719696393436652, "METHOTREXATE": 2.237128838322657, "MICARDIS": 1.800312821862906, "MMRVAXPRO": 8.140673305398892, "NAGLAZYME": 4.013183544048117, "NIMENRIX": 1.8999162082386305, "NUCALA": 3.374091730374153, "OLANZAPINE": 0.4942789135731236, "OMALIZUMAB": 1.6071200189789283, "PEGASYS": 0.4361676922959839, "PEGINTRON": 0.4878168389525648, "PREVENAR": 4.405390526535821, "PRIVIGEN": 1.545438492659031, "RINVOQ": 1.1176310143679375, "RITUXIMAB": 1.0887413854890802, "ROACTEMRA": 1.9943693417873865, "SIMPONI": 13.121279774519005, "SOLIRIS": 1.5252079585588243, "SPIKEVAX": 0.2916625507061219, "STELARA": 1.9093160993802205, "SUTENT": 0.5455721878564802, "SYNFLORIX": 41.23229230924512, "TAMIFLU": 0.9511770124216232, "TOZINAMERAN": 0.4802104994182916, "TRELEGY": 1.032983277582479, "VAXZEVRIA": 0.2747680734547592, "XELJANZ": 1.9220145474707653, "XOLAIR": 2.451456662646564, "ZOSTAVAX": 1.5337161201875658, "ZYPREXA": 1.061633086777249, "null": 1.2714198125297194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9216.json
new file mode 100644
index 00000000000..73a67f9c9fa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9216.json
@@ -0,0 +1 @@
+{"null": 0.9542771963622304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9217.json
new file mode 100644
index 00000000000..d1aeaed14bc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9217.json
@@ -0,0 +1 @@
+{"BENLYSTA": 6.261594681430518, "BUDESONIDE": 8.700246272217626, "CIMZIA": 5.90320101543447, "COSENTYX": 6.54313093922768, "ENBREL": 2.7179203669150285, "ENTYVIO": 4.278141247368636, "GARDASIL": 5.188792845996884, "HIZENTRA": 7.548730092672092, "HUMALOG": 1.5469663706061234, "METHOTREXATE": 3.10339538373158, "PEGASYS": 1.3454661535180847, "STELARA": 2.115780125229289, "TOZINAMERAN": 0.661884924942578, "VAXZEVRIA": 0.1363114947963145, "XELJANZ": 8.58749260771413, "XOLAIR": 2.425971990554596, "null": 1.2926428979073994}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9218.json
new file mode 100644
index 00000000000..0d5ee1c5f5f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9218.json
@@ -0,0 +1 @@
+{"null": 1.0836455511485923}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9219.json
new file mode 100644
index 00000000000..bebdfc048ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9219.json
@@ -0,0 +1 @@
+{"SYNFLORIX": 1141.1071288927312, "null": 1.477665877170942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/922.json
index 04f83c0802b..71218131cac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/922.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/922.json
@@ -1 +1 @@
-{"null": 2.119843710264686}
\ No newline at end of file
+{"ALDARA": 194.16432212653245, "AMELUZ": 428.25188660894895, "BUPRENORPHINE": 9.483271172788715, "LANTUS": 2.942659601520447, "NEULASTA": 147.94494347623447, "SIMPONI": 11.47787761453078, "null": 2.010141878787008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9220.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9220.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9221.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9221.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9222.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9222.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9223.json
new file mode 100644
index 00000000000..b0c7925e37f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9223.json
@@ -0,0 +1 @@
+{"PEGASYS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9224.json
new file mode 100644
index 00000000000..70107147bf5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9224.json
@@ -0,0 +1 @@
+{"TASIGNA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9225.json
new file mode 100644
index 00000000000..4f413fe2dff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9225.json
@@ -0,0 +1 @@
+{"BOSULIF": 113.38880249549912, "BOSUTINIB": 343.68706501491647, "DASATINIB": 512.8557772777307, "ICLUSIG": 93.7088246239684, "IMATINIB": 161.73462635180908, "NILOTINIB": 196.87095117596877, "SPRYCEL": 192.4662638449781, "TASIGNA": 41.0443062034632, "null": 0.0668655850976496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9226.json
new file mode 100644
index 00000000000..40cebb92751
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9226.json
@@ -0,0 +1 @@
+{"ICLUSIG": 2288.780376911525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9227.json
new file mode 100644
index 00000000000..bbfd9fd2e28
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9227.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 26.63528147586704, "FORXIGA": 74.79459415392452, "JARDIANCE": 259.6650755421261, "VIAGRA": 12.475380514967512, "null": 0.5253807133512028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9228.json
new file mode 100644
index 00000000000..3639fc7c7e9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9228.json
@@ -0,0 +1 @@
+{"COSENTYX": 227.25343412944676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9229.json
new file mode 100644
index 00000000000..dbc340122da
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9229.json
@@ -0,0 +1 @@
+{"BONVIVA": 6.178977510161345, "CELECOXIB": 9.44461549207107, "COMIRNATY": 1.0206832062267366, "CRESEMBA": 18.152061890242305, "EBIXA": 12.852828780432867, "ELIQUIS": 1.9583454279773715, "ENTRESTO": 0.8202652232306413, "EVISTA": 4.419420742168093, "FASLODEX": 1.856437577872559, "FORSTEO": 4.457912071928293, "LEVOFLOXACIN": 2.3870675361416094, "PEGASYS": 1.0315545439107583, "PROTELOS": 27.176896564318834, "RINVOQ": 3.910286132817981, "ROACTEMRA": 2.584713732783365, "SIMPONI": 1.4450568490592914, "SPIKEVAX": 0.6317243552883437, "STELARA": 0.6952951713131148, "TOZINAMERAN": 0.3241758072919331, "VAXZEVRIA": 1.0230536120428222, "XELJANZ": 0.8100235191324955, "XOLAIR": 0.6553669689870473, "null": 1.829490753988736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/923.json
index a54945737ab..87bc782ba27 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/923.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/923.json
@@ -1 +1 @@
-{"null": 2.779548869789919}
\ No newline at end of file
+{"QUTENZA": 4101.869131213314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9230.json
new file mode 100644
index 00000000000..eaece8fdbe7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9230.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.7738207013630476, "PROTELOS": 1201.3054046318136, "null": 0.4786410390723225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9231.json
new file mode 100644
index 00000000000..5ffbe07a7b3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9231.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.666078380874551, "SPIKEVAX": 0.962672589310722, "VAXZEVRIA": 2.2106849976023284, "null": 0.692273913526651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9232.json
new file mode 100644
index 00000000000..b28cc5c4981
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9232.json
@@ -0,0 +1 @@
+{"null": 1.0697945780850726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9233.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9233.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9234.json
new file mode 100644
index 00000000000..ce49eb2e108
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9234.json
@@ -0,0 +1 @@
+{"DELAMANID": 93.89526946675883, "OLANZAPINE": 7.32398977372985, "null": 2.4183239658412656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9235.json
new file mode 100644
index 00000000000..80ee148ee49
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9235.json
@@ -0,0 +1 @@
+{"null": 1.3795944005902652}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9236.json
new file mode 100644
index 00000000000..7235cffca44
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9236.json
@@ -0,0 +1 @@
+{"ZYPREXA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9237.json
new file mode 100644
index 00000000000..8b5fa046055
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9237.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.689646917721063, "VAXZEVRIA": 1.83392614542962}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9238.json
new file mode 100644
index 00000000000..8e1ae20cd10
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9238.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.0764877544495752, "GARDASIL": 8.609841751386828, "PRIVIGEN": 25.70397190639976, "VAXZEVRIA": 0.7640482306910452, "null": 0.9013541574166284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9239.json
new file mode 100644
index 00000000000..de319d10e20
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9239.json
@@ -0,0 +1 @@
+{"LUTETIUM": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/924.json
index 1a2070953d3..128afe5da4d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/924.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/924.json
@@ -1 +1 @@
-{"null": 3.191864984008677}
\ No newline at end of file
+{"BUPRENORPHINE": 15.427691384519546, "EVRA": 126.4377489659286, "VAXZEVRIA": 0.1104102151202978, "null": 8.357066210872937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9240.json
new file mode 100644
index 00000000000..2b70a90e6bb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9240.json
@@ -0,0 +1 @@
+{"null": 1.1188146268798724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9241.json
new file mode 100644
index 00000000000..5bc7cac5c6f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9241.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 8.124646397624387, "VORICONAZOLE": 135.0367952619468, "null": 0.7732958737199956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9242.json
new file mode 100644
index 00000000000..fd0151db097
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9242.json
@@ -0,0 +1 @@
+{"PEMBROLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9243.json
new file mode 100644
index 00000000000..1933c4a1896
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9243.json
@@ -0,0 +1 @@
+{"BYETTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9244.json
new file mode 100644
index 00000000000..ccfbb1a8c08
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9244.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.3435725346605812, "AIMOVIG": 2.331142584459237, "ARAVA": 0.5876601054919481, "AUBAGIO": 0.310771902951657, "AZACITIDINE": 2.110253887541604, "BELIMUMAB": 3.68058642349498, "BENLYSTA": 0.571562212215308, "BEOVU": 5.0861089066018605, "BRAFTOVI": 0.9450403617333212, "BRINTELLIX": 0.8229815239751137, "BYDUREON": 0.889241766093827, "CHAMPIX": 1.227447802329681, "CICLOSPORIN": 0.3474769517550738, "CIMZIA": 0.172672661769089, "COMIRNATY": 1.4029527760923988, "COSENTYX": 1.4312541773459515, "CYMBALTA": 0.8646525063557093, "DEXAMETHASONE": 0.428325249291743, "ELIQUIS": 0.0744064394893525, "ENBREL": 0.6967790229541226, "ENTRESTO": 0.6347630032174051, "ENTYVIO": 0.9605407880667552, "ERENUMAB": 10.026118124329455, "EYLEA": 6.237245659391273, "FLEBOGAMMA": 4.520342021563733, "GARDASIL": 7.178150575827919, "HIZENTRA": 1.9125329509856028, "HUMAN": 1.9625309116380891, "HUMIRA": 0.2907723971585584, "HYDROCORTISONE": 0.8144753183289929, "IBRANCE": 0.1190382295293803, "IBUPROFEN": 0.3884642209474673, "JETREA": 29.870651979182032, "KAFTRIO": 0.8763869002156642, "KEPPRA": 0.5285650654221942, "KEYTRUDA": 0.1592126800535915, "KIOVIG": 2.932579084265248, "LEVETIRACETAM": 0.3982861323484683, "LEVOFLOXACIN": 0.342591422376426, "LUXTURNA": 33.09864119134382, "LYRICA": 0.588570427914085, "MEKINIST": 1.201010936024705, "MENVEO": 5.292681490078892, "METHOTREXATE": 0.4158314348264652, "MMRVAXPRO": 1.4558555581688593, "MODERNA": 0.5355183719870643, "NEVANAC": 7.935524251149896, "NEXAVAR": 0.1655768238400117, "NIMENRIX": 1.944399681046213, "OCRELIZUMAB": 1.1454815483298346, "OMALIZUMAB": 0.3693297754183912, "OPSUMIT": 0.2795658537226157, "PEGASYS": 0.9314650110404882, "PEGINTERFERON": 0.6230875763605015, "PEGINTRON": 0.6001594203808143, "PREGABALIN": 0.8872726553471132, "PRIVIGEN": 9.29144868480372, "SHINGRIX": 2.1545617429604995, "SILDENAFIL": 1.1001507963048, "SOLIRIS": 0.4047200560238289, "SPIKEVAX": 1.0712199240216702, "SPINRAZA": 1.453186665373654, "STELARA": 0.628433831598742, "SUTENT": 0.097223194876266, "TAMIFLU": 0.5853570237514535, "TOZINAMERAN": 2.35661026962139, "TWINRIX": 1.09678767664047, "VAXZEVRIA": 2.4120326851080343, "VFEND": 13.444177500587218, "VIAGRA": 1.2216612767239967, "VIMPAT": 0.7265703086882507, "VORICONAZOLE": 2.1909299344394944, "XALKORI": 1.6241340402845728, "XELJANZ": 0.1251945359768548, "XOLAIR": 0.4020020099181058, "ZOSTAVAX": 0.6107737872701754, "ZYPREXA": 0.2088116570516697, "null": 0.6884359633105648}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9245.json
new file mode 100644
index 00000000000..f7b1ac57534
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9245.json
@@ -0,0 +1 @@
+{"AZILECT": 37.23206085361342, "BEOVU": 17.3774057964473, "BRINTELLIX": 1.7878520672514862, "BYDUREON": 1.6616962504589865, "CHAMPIX": 1.739114824163544, "COMIRNATY": 1.0909678657119015, "CYMBALTA": 0.975214210728734, "ERENUMAB": 19.81779697081929, "ESOMEPRAZOLE": 4.333662084723042, "EYLEA": 9.574374371771064, "FASLODEX": 1.881136037808424, "GARDASIL": 1.2888242931387055, "JETREA": 406.7610016231488, "KEPPRA": 0.8854892435074535, "LANTUS": 0.7759537810175597, "PEGASYS": 0.4374189162995666, "PEGINTRON": 0.9277771864252724, "SPIKEVAX": 0.7623278822134306, "STELARA": 1.4955744110048592, "SUTENT": 0.3489840106825732, "TOZINAMERAN": 2.367632012385012, "VAXZEVRIA": 1.4667168678870135, "VFEND": 14.82579612203931, "VIAGRA": 6.895560408642696, "VORICONAZOLE": 5.974649759405092, "VOTRIENT": 0.9754691112840158, "XALKORI": 29.1764804164103, "null": 0.7786552473401096}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9246.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9246.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9247.json
new file mode 100644
index 00000000000..8b18d43f9b2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9247.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.6244963760165655, "ADENURIC": 3.581741773776534, "AERIUS": 4.256961882423221, "AIMOVIG": 1.1694428958686964, "ALEMTUZUMAB": 1.3132467394701808, "ANAKINRA": 13.539737243374596, "APROVEL": 2.9198133270704365, "ARAVA": 0.3673063001740557, "ATAZANAVIR": 1.4581795972252247, "AUBAGIO": 0.3749761372515754, "AZATHIOPRINE": 1.423644871131558, "BENLYSTA": 1.1284891637256806, "BOSULIF": 1.55255679935935, "BRAFTOVI": 2.1245148090462034, "BRINTELLIX": 1.37167680859424, "BUDESONIDE": 0.823161869775051, "CAPRELSA": 20.36682090496372, "CELLCEPT": 0.7139409906180084, "CHAMPIX": 0.2778908540744421, "CICLOSPORIN": 0.869835393950757, "CIMZIA": 0.3943661680341265, "CLOPIDOGREL": 0.4958911719928481, "COAPROVEL": 4.373483099353235, "COBIMETINIB": 35.91514071915189, "COMIRNATY": 0.3073935150494523, "COSENTYX": 1.2174017948843254, "COTELLIC": 48.65962371824853, "CYMBALTA": 0.9304288100817796, "DASATINIB": 6.910562087939298, "DESLORATADINE": 5.9867980874682, "ELIQUIS": 0.3007567411186742, "EMTRIVA": 15.25648437215026, "ENBREL": 1.1281557493915175, "ENTYVIO": 1.1550841767992768, "ESBRIET": 42.79986465523282, "EXFORGE": 1.1825303493374295, "GARDASIL": 1.9652038248685704, "HUMALOG": 0.194483111196933, "HUMIRA": 0.7715553789711089, "IBRANCE": 0.3622962736415698, "IRBESARTAN": 2.862349617962733, "JANUVIA": 0.4003805371784238, "KAFTRIO": 1.1830314089643914, "KEPPRA": 1.0074165431016675, "LANTUS": 0.2579290031180287, "LEVETIRACETAM": 0.5906797532100646, "LEVOFLOXACIN": 1.374609617459532, "LYRICA": 0.567348010251015, "METHOTREXATE": 2.379235199989916, "MICARDISPLUS": 10.022856636163448, "MULTAQ": 6.33796335013457, "MYCOPHENOLATE": 1.3326730875207922, "NEXAVAR": 0.2530848751356266, "OLANZAPINE": 0.564704938234025, "OLYSIO": 61.43671189451053, "OMALIZUMAB": 0.5578139569876045, "PANTOPRAZOLE": 1.5009629897161492, "PEGASYS": 1.4097652230545314, "PEGINTRON": 1.168158584489862, "PIRFENIDONE": 81.87302339553328, "PLAVIX": 0.4640088136297061, "RASILEZ": 1.8690756487807123, "RIBAVIRIN": 1.4885092812979226, "ROACTEMRA": 0.7848500338761122, "RUBRACA": 6.377257826963176, "SIMEPREVIR": 23.011967925880302, "SIMPONI": 0.4294026442000924, "SOVALDI": 2.332324622538988, "SPIKEVAX": 0.2235816223823991, "SPRYCEL": 0.6756925646989667, "STELARA": 0.5896758762832318, "SUTENT": 0.229516650564421, "TAMIFLU": 0.6493782540214317, "TOZINAMERAN": 0.5699894504491386, "VAXZEVRIA": 0.4392728239611028, "VEMURAFENIB": 36.187932257270695, "VFEND": 31.180583209106384, "VORICONAZOLE": 42.82782057483317, "VOTRIENT": 0.3671415971266182, "XELJANZ": 0.3148674511770326, "XOLAIR": 1.5093300071715747, "ZELBORAF": 57.499578519567216, "ZOSTAVAX": 0.2390758422683395, "ZYPREXA": 0.2544729719503206, "null": 1.326055017097822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9248.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9248.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9249.json
new file mode 100644
index 00000000000..48d9bba32c1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9249.json
@@ -0,0 +1 @@
+{"null": 1.6969795189082784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/925.json
index ae44248f70f..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/925.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/925.json
@@ -1 +1 @@
-{"ABILIFY": 5.5813945059498815, "BRINTELLIX": 8.610737689359066, "CHAMPIX": 6.982177102643804, "CYMBALTA": 3.915435412024372, "CYTARABINE": 9.40081124182709, "LATUDA": 32.33995462696452, "OLANZAPINE": 20.51866285655935, "PEGASYS": 4.610085778720421, "PEGINTRON": 4.966625361874993, "ZYPREXA": 8.433214361337289, "null": 1.5704210139510215}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9250.json
new file mode 100644
index 00000000000..aea06151a82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9250.json
@@ -0,0 +1 @@
+{"null": 0.4546645556637538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9251.json
new file mode 100644
index 00000000000..36ec61c3486
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9251.json
@@ -0,0 +1 @@
+{"null": 4.8229311646374615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9252.json
new file mode 100644
index 00000000000..4fe4305d8b2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9252.json
@@ -0,0 +1 @@
+{"CHAMPIX": 23.912197265454942, "CYMBALTA": 4.565859215679509, "FYCOMPA": 70.48429610073784, "JARDIANCE": 2.784472543182309, "KEPPRA": 7.960560257800855, "LATUDA": 13.267118074208542, "PEGASYS": 2.0237567444924363, "SUBOXONE": 8.062619897563344, "ZYPREXA": 3.459840721567651, "null": 2.5511916710000557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9253.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9253.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9254.json
new file mode 100644
index 00000000000..2eda6dee056
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9254.json
@@ -0,0 +1 @@
+{"APIXABAN": 1.3760101157171425, "CHAMPIX": 2.844249294995618, "COMIRNATY": 1.1377168891759497, "CYMBALTA": 1.914807999587148, "ELIQUIS": 0.6181669736445302, "ESOMEPRAZOLE": 152.4321336546522, "EVENITY": 15.201333457368364, "EXFORGE": 2.4902315446560466, "FORXIGA": 2.0754680621713124, "GARDASIL": 1.0563284607445784, "INLYTA": 2.158643434180084, "JANUVIA": 1.815139394075142, "JARDIANCE": 1.6592657658467085, "JEVTANA": 7.954452546646241, "KEYTRUDA": 3.06148137571326, "LANTUS": 1.9727734518151705, "LATUDA": 3.953999088860821, "METFORMIN": 29.53439335498188, "NEXAVAR": 2.456040975280282, "NUCALA": 1.8162026409821248, "OFEV": 9.419122685306077, "OPDIVO": 3.407527251903232, "OPSUMIT": 1.0887703387159955, "SPIKEVAX": 0.3140438973096069, "STIVARGA": 2.156306249538904, "SUTENT": 0.5681962724203101, "TOZINAMERAN": 0.1272472339810239, "VAXZEVRIA": 0.055804270635242, "XELJANZ": 1.475681026327761, "XOFIGO": 6.915306453406476, "XTANDI": 2.315673831297754, "null": 0.8059012056362411}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9255.json
new file mode 100644
index 00000000000..2472c8fcc56
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9255.json
@@ -0,0 +1 @@
+{"ABATACEPT": 2.920296795161282, "ARAVA": 0.6964516490114596, "ATRIPLA": 0.1845103912445765, "AVANDIA": 1.1743500048898214, "CIMZIA": 0.8853683180665816, "COMIRNATY": 0.0935454354865339, "ENBREL": 0.7279282772525867, "LANTUS": 0.5334599835489013, "PLAVIX": 8.680829723214543, "SPIKEVAX": 0.0383889728925473, "TOZINAMERAN": 0.1433443424600991, "VAXZEVRIA": 0.0668377955745653, "null": 9.079889628000537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9256.json
new file mode 100644
index 00000000000..3aad96604ac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9256.json
@@ -0,0 +1 @@
+{"SPINRAZA": 263.044119806319}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9257.json
new file mode 100644
index 00000000000..9733aabd887
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9257.json
@@ -0,0 +1 @@
+{"null": 2.1981287487574592}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9258.json
new file mode 100644
index 00000000000..e604e950d6f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9258.json
@@ -0,0 +1 @@
+{"null": 1.8569375605660925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9259.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9259.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/926.json
index 1677fe3935c..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/926.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/926.json
@@ -1 +1 @@
-{"null": 2.9785366220926184}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9260.json
new file mode 100644
index 00000000000..4f4b75eaacc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9260.json
@@ -0,0 +1 @@
+{"null": 3.153209751911753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9261.json
new file mode 100644
index 00000000000..f6b4067630a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9261.json
@@ -0,0 +1 @@
+{"null": 2.214696680158027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9262.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9262.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9263.json
new file mode 100644
index 00000000000..ad74792f2a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9263.json
@@ -0,0 +1 @@
+{"NUCALA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9264.json
new file mode 100644
index 00000000000..257a5e16591
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9264.json
@@ -0,0 +1 @@
+{"null": 9.568565666792647}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9265.json
new file mode 100644
index 00000000000..b9b7249ed4b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9265.json
@@ -0,0 +1 @@
+{"null": 2.653709282728216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9266.json
new file mode 100644
index 00000000000..09625d32d70
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9266.json
@@ -0,0 +1 @@
+{"null": 1.5345798162876387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9267.json
new file mode 100644
index 00000000000..8c46af10454
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9267.json
@@ -0,0 +1 @@
+{"AFINITOR": 1.1089991309611045, "AVASTIN": 2.990348576193296, "BEVACIZUMAB": 3.01975188869474, "BIKTARVY": 14.009123986857192, "CICLOSPORIN": 0.9482457176717444, "CLOPIDOGREL": 0.6741553246802892, "COMIRNATY": 0.2906441644704243, "COSENTYX": 2.1477169806082195, "DEXAMETHASONE": 1.3370156443625754, "ELIQUIS": 0.5015589252928049, "EXFORGE": 1.946677866082773, "FORSTEO": 1.8673138235509776, "KEYTRUDA": 0.6336021546174181, "KISQALI": 5.251146733616541, "LEFLUNOMIDE": 11.873463724173384, "LEVOFLOXACIN": 1.0080515419171454, "MEKINIST": 1.752654655941918, "OPTIMARK": 8.106690691395034, "PEGASYS": 1.095903617983326, "PEGINTRON": 0.7603700429886495, "PLAVIX": 0.667456242772608, "SPIKEVAX": 0.2177193994639483, "SUTENT": 2.337015348270204, "TOZINAMERAN": 0.2838686913571028, "VAXZEVRIA": 0.1876178636161058, "VOTRIENT": 3.5697638270200724, "XOLAIR": 2.2232093522323515, "null": 2.143231299325057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9268.json
new file mode 100644
index 00000000000..82adb3895d8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9268.json
@@ -0,0 +1 @@
+{"ABILIFY": 6.715642544640618, "BUPRENORPHINE": 6.001751371460073, "COMIRNATY": 1.1032328242510072, "FENTANYL": 11.245898962901409, "SPIKEVAX": 1.1903495710789895, "SUBOXONE": 5.515729708118398, "TOZINAMERAN": 2.014464291296056, "VAXZEVRIA": 2.3748896071797536, "null": 0.7481739191420187}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9269.json
new file mode 100644
index 00000000000..a958efb198a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9269.json
@@ -0,0 +1 @@
+{"HUMIRA": 56.872705957459154, "null": 0.4797850599993831}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/927.json
index de1ba260398..39f8c6a7907 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/927.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/927.json
@@ -1 +1 @@
-{"ABILIFY": 15.764130373977425, "AIMOVIG": 1.7564357960809656, "ARIPIPRAZOLE": 1.3001243519385588, "BIKTARVY": 5.280026385650897, "CHAMPIX": 8.401940997089007, "CYMBALTA": 4.076890221810858, "ENBREL": 5.963753788941821, "FASLODEX": 1.2895816658665802, "KEPPRA": 1.1348558940789557, "LANTUS": 1.156654667071238, "LATUDA": 57.76609162170238, "LYRICA": 2.1188013758066866, "OLANZAPINE": 6.2101257248433255, "PEGASYS": 2.7897418349701733, "PEGINTRON": 1.4672641660028682, "SIFROL": 14.717135730229309, "SUBOXONE": 2.6546823123268464, "TAMIFLU": 1.4401304283761929, "VIAGRA": 2.4014734358127616, "VIMPAT": 3.416398787187151, "XYREM": 6.017577541938056, "ZONISAMIDE": 47.7760182561827, "ZOSTAVAX": 1.8915155912620447, "ZYPREXA": 7.550605157566669, "null": 2.095435750385965}
\ No newline at end of file
+{"COMIRNATY": 3.436574257038675, "SPIKEVAX": 1.705480716203982, "VAXZEVRIA": 1.7991792505906852, "null": 0.4378626035092252}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9270.json
new file mode 100644
index 00000000000..7c0a93f1006
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9270.json
@@ -0,0 +1 @@
+{"JANUVIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9271.json
new file mode 100644
index 00000000000..e4993dea474
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9271.json
@@ -0,0 +1 @@
+{"GARDASIL": 31.89632822653764, "null": 0.4100884269517391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9272.json
new file mode 100644
index 00000000000..8651cc2a8ce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9272.json
@@ -0,0 +1 @@
+{"OLANZAPINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9273.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9273.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9274.json
new file mode 100644
index 00000000000..0c9775254b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9274.json
@@ -0,0 +1 @@
+{"null": 0.7743032315660294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9275.json
new file mode 100644
index 00000000000..cd95caf2e0a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9275.json
@@ -0,0 +1 @@
+{"null": 3.507817362457581}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9276.json
new file mode 100644
index 00000000000..aa38c531f9c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9276.json
@@ -0,0 +1 @@
+{"null": 1.2714126242747026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9277.json
new file mode 100644
index 00000000000..03570468e0c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9277.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 19.065034741136685, "OPDIVO": 66.88881843522914, "null": 0.8349763786897797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9278.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9278.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9279.json
new file mode 100644
index 00000000000..87adc83f5bd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9279.json
@@ -0,0 +1 @@
+{"null": 0.8565727309887768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/928.json
index 82fe5841fc7..095d52643ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/928.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/928.json
@@ -1 +1 @@
-{"null": 2.4815607600334006}
\ No newline at end of file
+{"COMIRNATY": 0.559294880105233, "SPIKEVAX": 0.8298308913301591, "VAXZEVRIA": 2.1186530148071183, "null": 1.1081336474150711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9280.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9280.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9281.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9281.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9282.json
new file mode 100644
index 00000000000..a3b50734bfc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9282.json
@@ -0,0 +1 @@
+{"LANTUS": 2.705860199789325, "null": 3.0634015744159098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9283.json
new file mode 100644
index 00000000000..bbc434b9dd3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9283.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 4.299157720822782, "COMIRNATY": 0.1910632638849928, "CYMBALTA": 3.324238055229316, "HYDROCORTISONE": 13.078093643284394, "OLANZAPINE": 5.49750503197662, "SOMATROPIN": 63.016160763225535, "ZYPREXA": 3.432428826828059, "null": 2.189595108623794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9284.json
new file mode 100644
index 00000000000..c0a23d1a012
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9284.json
@@ -0,0 +1 @@
+{"null": 3.347618680517989}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9285.json
new file mode 100644
index 00000000000..317fa003770
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9285.json
@@ -0,0 +1 @@
+{"null": 8.819188985463231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9286.json
new file mode 100644
index 00000000000..5d35a0d07f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9286.json
@@ -0,0 +1 @@
+{"ATRIPLA": 2.7535101659207224, "null": 0.798051963043636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9287.json
new file mode 100644
index 00000000000..689620d40ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9287.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.936667536698194, "TOZINAMERAN": 3.2525906373978835, "VAXZEVRIA": 1.0630428980192108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9288.json
new file mode 100644
index 00000000000..f4b26017aeb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9288.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.0529715382668807, "null": 0.32278776867891}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9289.json
new file mode 100644
index 00000000000..54a2c525b71
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9289.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.843138547433268, "GARDASIL": 3.54756628266662, "SPIKEVAX": 1.836029661130395, "TOZINAMERAN": 2.81306213436927, "VAXZEVRIA": 0.6251853991191807, "null": 0.2258562180979546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/929.json
index 3fe87d2a15a..a4c5ef24614 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/929.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/929.json
@@ -1 +1 @@
-{"FENTANYL": 231.2706188708904}
\ No newline at end of file
+{"null": 3.3020061659618274}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9290.json
new file mode 100644
index 00000000000..7533bc0d3b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9290.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 4.959180047079559, "CICLOSPORIN": 10.600639155897865, "COMIRNATY": 0.782836199310876, "ICLUSIG": 53.93698520196627, "SPIKEVAX": 0.607510995801925, "VAXZEVRIA": 0.4199024748321097, "null": 0.2897149684771822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9291.json
new file mode 100644
index 00000000000..798344088db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9291.json
@@ -0,0 +1 @@
+{"null": 1.87083069145616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9292.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9292.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9293.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9293.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9294.json
new file mode 100644
index 00000000000..503423d36de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9294.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 18.197897702411847, "CYMBALTA": 4.301143729361999, "SUBOXONE": 21.27051078674856, "null": 1.3030057578817955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9295.json
new file mode 100644
index 00000000000..2652ad31f79
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9295.json
@@ -0,0 +1 @@
+{"null": 0.9728078020631838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9296.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9296.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9297.json
new file mode 100644
index 00000000000..ab4d0380b5a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9297.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 19.87366516423533, "COMBIVIR": 24.546871304112383, "COMIRNATY": 0.1248239248559989, "EPIVIR": 34.128575768762055, "KEPPRA": 5.101840223211001, "null": 1.5360259572125825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9298.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9298.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9299.json
new file mode 100644
index 00000000000..ffa1c391806
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9299.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 529.150652957763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/93.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/93.json
index db0a782c970..20c586a6c0a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/93.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/93.json
@@ -1 +1 @@
-{"null": 1.2477555428486908}
\ No newline at end of file
+{"ARAVA": 3.689522338401433, "CICLOSPORIN": 17.34342310253314, "null": 1.2826626497445768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/930.json
index d54884da64d..43aa978e0a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/930.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/930.json
@@ -1 +1 @@
-{"MICARDIS": 36.44823989957512, "null": 2.101633699983286}
\ No newline at end of file
+{"ALDARA": 364.0892757176776, "BUPRENORPHINE": 7.757389773055307, "QUTENZA": 70.4415342237246, "null": 6.468014811504156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9300.json
new file mode 100644
index 00000000000..89f5ac97451
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9300.json
@@ -0,0 +1 @@
+{"null": 1.864835232052114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9301.json
new file mode 100644
index 00000000000..4a0692e7a24
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9301.json
@@ -0,0 +1 @@
+{"CEFTAROLINE": 1995.0411285213304, "COMIRNATY": 0.2733387615330219, "null": 1.791652560932195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9302.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9302.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9303.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9303.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9304.json
new file mode 100644
index 00000000000..8aca0746983
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9304.json
@@ -0,0 +1 @@
+{"FENTANYL": 81.01986372259259, "null": 1.2097537478347755}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9305.json
new file mode 100644
index 00000000000..9091ab369eb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9305.json
@@ -0,0 +1 @@
+{"null": 5.968983671879812}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9306.json
new file mode 100644
index 00000000000..9c7eb7c2c84
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9306.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1831256358167657, "NEXAVAR": 38.92430833213189, "STIVARGA": 51.83478744048034, "SUTENT": 14.826463525322955, "null": 0.4976135664480136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9307.json
new file mode 100644
index 00000000000..b054164dac3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9307.json
@@ -0,0 +1 @@
+{"null": 1.2467472781160776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9308.json
new file mode 100644
index 00000000000..118f4cb6df6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9308.json
@@ -0,0 +1 @@
+{"AMGEVITA": 905.5877671046986, "BUPRENORPHINE": 7.220886243513024, "CHOLESTAGEL": 484.1335908908842, "COMIRNATY": 0.5414927475257565, "COSENTYX": 3.9624910411322833, "ENBREL": 9.435290899187736, "HARVONI": 14.933772300369856, "LEVOFLOXACIN": 5.183259912473844, "OPTIMARK": 5.216795573526623, "SPIKEVAX": 0.3034550278879897, "TOZINAMERAN": 1.1497392640535116, "VAXZEVRIA": 0.2360640634104875, "XELJANZ": 2.5758096219927307, "ZOSTAVAX": 3.978853681808197, "null": 1.0695371011856845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9309.json
new file mode 100644
index 00000000000..ace0291cabf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9309.json
@@ -0,0 +1 @@
+{"JARDIANCE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/931.json
index 6ec2646a8c4..cc849d850a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/931.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/931.json
@@ -1 +1 @@
-{"APTIVUS": 39404.1228813144}
\ No newline at end of file
+{"null": 1.3096339481926855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9310.json
new file mode 100644
index 00000000000..604703bd3a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9310.json
@@ -0,0 +1 @@
+{"null": 0.8452258041202194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9311.json
new file mode 100644
index 00000000000..2d15970b8a2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9311.json
@@ -0,0 +1 @@
+{"BORTEZOMIB": 202.4132823908067, "CARFILZOMIB": 126.22919797924509, "DARZALEX": 54.03659493762508, "DEXAMETHASONE": 32.851093145064, "REVLIMID": 107.80675680982564, "null": 0.8493076354999529}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9312.json
new file mode 100644
index 00000000000..9e0679badac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9312.json
@@ -0,0 +1 @@
+{"APIXABAN": 0.3310821071616295, "ARANESP": 1.0824687857428623, "BELANTAMAB": 81.30944715832501, "BORTEZOMIB": 123.95715837787353, "BUSULFAN": 0.6684708868321367, "CAELYX": 6.550785786912292, "CARFILZOMIB": 250.0388566141349, "CARMUSTINE": 2.309216098104557, "CELLCEPT": 1.0085678460693257, "CICLOSPORIN": 0.4555125135648185, "COMIRNATY": 0.0335114194096875, "CYTARABINE": 0.4227665408762665, "DARATUMUMAB": 110.3570070557018, "DARZALEX": 131.17081336307456, "DEXAMETHASONE": 32.500897555139176, "ELIQUIS": 0.3115738397320722, "EMPLICITI": 115.28354830433628, "ENBREL": 0.6014905004829133, "EVENITY": 1.391900026165089, "EXJADE": 0.8642002256271646, "FILGRASTIM": 2.186982839596736, "FORSTEO": 2.533891197232653, "HUMALOG": 0.2396561374549296, "IBRANCE": 0.1276382232023984, "IMNOVID": 88.85475027703849, "ISATUXIMAB": 120.19680629071564, "KYPROLIS": 62.7449831745164, "LENALIDOMIDE": 14.985335608817405, "MEKINIST": 0.6037297829672748, "MELPHALAN": 17.811635782609535, "NEULASTA": 0.8159283963902704, "NINLARO": 101.63486272063848, "NPLATE": 3.043583585862543, "POMALIDOMIDE": 168.79004554642137, "REVLIMID": 112.11239871542918, "SIMPONI": 0.394640000556926, "SOLIRIS": 0.652275166199218, "SPIKEVAX": 0.0240108837690345, "STELARA": 0.8380016523330177, "STRIBILD": 0.219827233899281, "SUTENT": 0.1042495278726668, "THALIDOMIDE": 49.61178118538482, "TOZINAMERAN": 0.0276474082932154, "VAXZEVRIA": 0.0086412628874021, "VELCADE": 42.29686851612029, "VENETOCLAX": 11.670601936418954, "VIAGRA": 0.3640091148189862, "XELJANZ": 0.1342400538111922, "XOLAIR": 0.4033426321747927, "ZOSTAVAX": 0.1898978958200096, "null": 1.906742673630288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9313.json
new file mode 100644
index 00000000000..57228b9a2f8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9313.json
@@ -0,0 +1 @@
+{"BORTEZOMIB": 184.7513470758042, "CAELYX": 21.28066622512318, "CARFILZOMIB": 310.2636980620203, "DARATUMUMAB": 136.46929935798, "DARZALEX": 84.71844872614702, "DEXAMETHASONE": 65.26945438935768, "KYPROLIS": 81.70648494324013, "NINLARO": 99.10039417222528, "POMALIDOMIDE": 93.22531068431744, "REVLIMID": 118.21232702146835, "THALIDOMIDE": 46.55714078620445, "null": 0.8415204178810197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9314.json
new file mode 100644
index 00000000000..c9904d9c4dd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9314.json
@@ -0,0 +1 @@
+{"BORTEZOMIB": 690.6130652070248, "CARFILZOMIB": 656.0675874662888, "DARZALEX": 50.34665769884432, "DEXAMETHASONE": 125.02506953041542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9315.json
new file mode 100644
index 00000000000..30380b6ee3a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9315.json
@@ -0,0 +1 @@
+{"null": 1.719128601799418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9316.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9316.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9317.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9317.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9318.json
new file mode 100644
index 00000000000..cf9338983a9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9318.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 4.401711987377291, "CICLOSPORIN": 27.697086047615397, "COMBIVIR": 71.219658842243, "null": 0.184798927459297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9319.json
new file mode 100644
index 00000000000..6deef1b8d6d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9319.json
@@ -0,0 +1 @@
+{"BORTEZOMIB": 139.77245146240406, "CARFILZOMIB": 185.71442302218583, "CICLOSPORIN": 8.26429960808271, "COMIRNATY": 0.0816278881798685, "DARZALEX": 76.77781212474392, "DEXAMETHASONE": 31.165884356227803, "FORSTEO": 4.2327796081995, "KYPROLIS": 100.71757198604698, "POMALIDOMIDE": 119.62528421273352, "REVLIMID": 116.34919170311956, "THALIDOMIDE": 74.41602336223518, "null": 0.968246412030249}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/932.json
index c6f372791e1..46d53b30fa5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/932.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/932.json
@@ -1 +1 @@
-{"ACTOS": 23.641552064340974, "ANORO": 1.27203784587992, "BYETTA": 1.0403944233554645, "ELIQUIS": 1.7335871028966274, "ESBRIET": 1.5634776878536405, "EXFORGE": 2.209249633112308, "FORXIGA": 2.7807098160331005, "JANUVIA": 1.486676116256599, "JARDIANCE": 3.225131579039912, "RINVOQ": 1.3172654096890988, "ROACTEMRA": 1.0837036057329006, "STELARA": 1.9862221974394416, "TOVIAZ": 1.0798752269231695, "TRELEGY": 2.6410840435154865, "VIAGRA": 1.284604201263595, "null": 9.444506687852456}
\ No newline at end of file
+{"ALDARA": 63.88590868536174, "BUPRENORPHINE": 6.100184107290469, "EVRA": 60.05365519160141, "OPSUMIT": 2.9149350982591145, "null": 15.762720213340636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9320.json
new file mode 100644
index 00000000000..60bfe474d2f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9320.json
@@ -0,0 +1 @@
+{"null": 1.306619988521472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9321.json
new file mode 100644
index 00000000000..d339d2d9fb1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9321.json
@@ -0,0 +1 @@
+{"SOLIRIS": 43.98045934079035, "null": 0.6693150753956462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9322.json
new file mode 100644
index 00000000000..9b9968c69e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9322.json
@@ -0,0 +1 @@
+{"BEVACIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9323.json
new file mode 100644
index 00000000000..f12da301311
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9323.json
@@ -0,0 +1 @@
+{"ADVATE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9324.json
new file mode 100644
index 00000000000..90eef23deff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9324.json
@@ -0,0 +1 @@
+{"ENOXAPARIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9325.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9325.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9326.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9326.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9327.json
new file mode 100644
index 00000000000..c75ff0e80f0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9327.json
@@ -0,0 +1 @@
+{"null": 2.319713095995556}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9328.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9328.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9329.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9329.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/933.json
index f02d2fa828e..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/933.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/933.json
@@ -1 +1 @@
-{"CICLOSPORIN": 13.669122458058936}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9330.json
new file mode 100644
index 00000000000..4aab17dd23b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9330.json
@@ -0,0 +1 @@
+{"null": 2.1571591563082437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9331.json
new file mode 100644
index 00000000000..d4332ebf6a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9331.json
@@ -0,0 +1 @@
+{"null": 1.3735331205207788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9332.json
new file mode 100644
index 00000000000..ad74792f2a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9332.json
@@ -0,0 +1 @@
+{"NUCALA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9333.json
new file mode 100644
index 00000000000..3a9d0cf08cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9333.json
@@ -0,0 +1 @@
+{"null": 2.118328606160788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9334.json
new file mode 100644
index 00000000000..ebf8735b431
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9334.json
@@ -0,0 +1 @@
+{"null": 0.9716065362989734}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9335.json
new file mode 100644
index 00000000000..02682addf62
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9335.json
@@ -0,0 +1 @@
+{"null": 1.1143824523374972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9336.json
new file mode 100644
index 00000000000..7be181ad7e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9336.json
@@ -0,0 +1 @@
+{"null": 0.9378624741989476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9337.json
new file mode 100644
index 00000000000..5369639f08e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9337.json
@@ -0,0 +1 @@
+{"TICAGRELOR": 471.91629779597486, "null": 1.1724972826029354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9338.json
new file mode 100644
index 00000000000..604703bd3a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9338.json
@@ -0,0 +1 @@
+{"null": 0.8452258041202194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9339.json
new file mode 100644
index 00000000000..a80a050eae3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9339.json
@@ -0,0 +1 @@
+{"ADENURIC": 17.24623624646984, "ARANESP": 3.3381821070898603, "CICLOSPORIN": 0.948979594990519, "COMIRNATY": 0.0286444578767753, "CYTARABINE": 3.861330290451181, "ELIQUIS": 0.8458854760407494, "IBRANCE": 1.2312880128584178, "ICLUSIG": 9.54351824708954, "JAKAVI": 15.916778242750372, "KEYTRUDA": 1.833821499209324, "LEMTRADA": 17.110926383647836, "LENALIDOMIDE": 51.18205160575494, "NEULASTA": 8.719795505914457, "NPLATE": 460.8840840660201, "PEGASYS": 4.764929184154894, "PEGINTRON": 1.2814586029400237, "RUXOLITINIB": 41.54108764443495, "SOLIRIS": 21.19407323280058, "SUTENT": 1.3995126332712935, "VAXZEVRIA": 0.0895119179084689, "null": 0.4770375855717895}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/934.json
index 6d55750d5d7..dbe5aa40fb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/934.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/934.json
@@ -1 +1 @@
-{"null": 2.739337169947462}
\ No newline at end of file
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9340.json
new file mode 100644
index 00000000000..d5cc8a841b6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9340.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.1543707271608937, "ABEMACICLIB": 5.768634076520544, "ABRAXANE": 1.9044746010383005, "ACTOS": 0.5452231294774978, "ADCETRIS": 1.0914173221910917, "ADCIRCA": 3.2246804373193183, "ADENURIC": 1.0654407453539123, "AFINITOR": 3.408985226189868, "AIMOVIG": 0.1140552251061342, "ALEMTUZUMAB": 0.8894172063035152, "ALIMTA": 5.816457706133234, "AMIKACIN": 0.7768721997425889, "AMINOSALICYLIC": 1.04556225301418, "ANAGRELIDE": 6.713019868553475, "ANGIOX": 2.9170750797567284, "APIXABAN": 0.2300316767031668, "ARANESP": 0.7758411268723376, "ARAVA": 0.2996899636623141, "ARIPIPRAZOLE": 1.3370123151439324, "ASPARAGINASE": 1.004607946373662, "ATAZANAVIR": 0.2745259702414706, "ATEZOLIZUMAB": 1.24573944460458, "AUBAGIO": 0.2388883375637381, "AVANDIA": 0.0431739064720046, "AVASTIN": 4.58148089002947, "AXICABTAGENE": 2.123433829948547, "AXITINIB": 0.9816243673410728, "AZACITIDINE": 5.2840529728928205, "AZATHIOPRINE": 1.2687856052415007, "BARACLUDE": 1.676794687114764, "BARICITINIB": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9341.json
new file mode 100644
index 00000000000..b91fc1d647e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9341.json
@@ -0,0 +1 @@
+{"ABATACEPT": 1.3244535317584016, "AFINITOR": 2.56685252510067, "ALIMTA": 1.714003921172142, "AMINOSALICYLIC": 6.496394947453721, "ANAGRELIDE": 70.73577353593751, "ARANESP": 0.7340933931271056, "ARAVA": 0.3728990244394589, "BEDAQUILINE": 20.88064800573933, "BOSULIF": 8.311839426802559, "BRILIQUE": 1.8117948683316896, "BUDESONIDE": 20.787473086451257, "BUSILVEX": 17.440617916739587, "CICLOSPORIN": 1.9876728823866108, "CLOPIDOGREL": 2.3401352799166206, "COMIRNATY": 0.239692350196277, "COSENTYX": 0.5965957478342465, "CYMBALTA": 0.3461302147188241, "CYTARABINE": 2.2922483742357858, "DACLATASVIR": 10.086642594741278, "DEXAMETHASONE": 1.5168266799534855, "ELIQUIS": 0.7323333864049013, "ENTYVIO": 2.3370937176270234, "EXJADE": 4.981653757931294, "FULVESTRANT": 2.1711819721110968, "GLIVEC": 4.857422139270834, "HUMIRA": 1.6750223412331935, "HYDROXYCARBAMIDE": 58.28767027844895, "IBRANCE": 1.1218689420636394, "JAKAVI": 55.84720009267695, "LEMTRADA": 1.7460153519013124, "MEKINIST": 1.9968626650882493, "METHOTREXATE": 0.6224310178466258, "NEXAVAR": 1.152353338405364, "NPLATE": 57.43959250496793, "NUCALA": 21.68549296758328, "OLANZAPINE": 0.7332314361623993, "PANTOPRAZOLE": 3.035546984945248, "PEGASYS": 1.180561357360045, "PEGINTRON": 0.5886487604244328, "PLAVIX": 0.3680740178078995, "RINVOQ": 4.767040776168548, "RUXOLITINIB": 25.26832647194433, "SOLIRIS": 3.2034060955091457, "SPIKEVAX": 0.0922826498616468, "SPRYCEL": 3.0766663670874514, "SUTENT": 1.027539077986768, "TASIGNA": 4.554184603347139, "TOZINAMERAN": 0.3810177941101386, "VAXZEVRIA": 0.1982598845916413, "XELJANZ": 1.042044795739857, "XOLAIR": 0.8875743496714239, "ZYPREXA": 1.9708852780372712, "null": 0.8563840384865986}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9342.json
new file mode 100644
index 00000000000..364fa9fe547
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9342.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 13.57034448414263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9343.json
new file mode 100644
index 00000000000..beadc515138
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9343.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 2.0030136862538224, "COMIRNATY": 0.1949122663070769, "DEXAMETHASONE": 3.203617010140706, "IBRANCE": 3.7231022466798698, "JAKAVI": 7.056240947713863, "LENALIDOMIDE": 159.68681439580797, "NPLATE": 28.565846645997446, "PEGASYS": 4.254657659778611, "RITUXIMAB": 5.042138197852018, "SUTENT": 2.5320072227222896, "TOZINAMERAN": 0.9142075472278592, "VAXZEVRIA": 0.4777656011575175, "null": 1.0084745831770572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9344.json
new file mode 100644
index 00000000000..6c39ecf5d84
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9344.json
@@ -0,0 +1 @@
+{"null": 0.6923840845856765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9345.json
new file mode 100644
index 00000000000..8679cb18d1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9345.json
@@ -0,0 +1 @@
+{"ENTRESTO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9346.json
new file mode 100644
index 00000000000..7f6ee4f8723
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9346.json
@@ -0,0 +1 @@
+{"PLAVIX": 51.64239492628506, "null": 1.3154389183015045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9347.json
new file mode 100644
index 00000000000..a7e90bb110e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9347.json
@@ -0,0 +1 @@
+{"null": 0.6588557304492099}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9348.json
new file mode 100644
index 00000000000..88de0a9ff8c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9348.json
@@ -0,0 +1 @@
+{"null": 0.9899765831711672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9349.json
new file mode 100644
index 00000000000..33ab6f811dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9349.json
@@ -0,0 +1 @@
+{"ADCIRCA": 63.65494520700914, "ELIQUIS": 2.6937267612060314, "OPSUMIT": 26.24370354018031, "SOLIRIS": 10.44128039054577, "SPRYCEL": 16.0038120670919, "TEMODAL": 56.856190435632094, "TEMOZOLOMIDE": 80.54199615150993, "TRACLEER": 11.800070091411234, "null": 0.5170264080399516}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/935.json
index 34e7a0795e8..925b681cbfe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/935.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/935.json
@@ -1 +1 @@
-{"null": 2.5322569562112758}
\ No newline at end of file
+{"null": 4.614304224319551}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9350.json
new file mode 100644
index 00000000000..c079965f928
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9350.json
@@ -0,0 +1 @@
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9351.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9351.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9352.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9352.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9353.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9353.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9354.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9354.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9355.json
new file mode 100644
index 00000000000..d655a9ceb93
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9355.json
@@ -0,0 +1 @@
+{"ZAVESCA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9356.json
new file mode 100644
index 00000000000..b62ebb290d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9356.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 7.0395387387915695, "COMIRNATY": 0.5021611401980396, "DARUNAVIR": 76.05346425004969, "DEXAMETHASONE": 17.64627020148265, "SPINRAZA": 61.1953986922888, "VAXZEVRIA": 0.2284313494056916, "null": 0.7004324142787056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9357.json
new file mode 100644
index 00000000000..eaa6e2aaf8e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9357.json
@@ -0,0 +1 @@
+{"AVAMYS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9358.json
new file mode 100644
index 00000000000..9bd78efcf9d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9358.json
@@ -0,0 +1 @@
+{"ANAKINRA": 87.23799643836266, "SOMATROPIN": 349.2422085660759, "null": 0.2016999082059885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9359.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9359.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/936.json
index 6f0482670e5..483045b2262 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/936.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/936.json
@@ -1 +1 @@
-{"null": 2.4172669215511355}
\ No newline at end of file
+{"COMIRNATY": 11.120928786800206, "SPIKEVAX": 1.7295173117875402, "VAXZEVRIA": 0.7744585673441121}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9360.json
new file mode 100644
index 00000000000..2b8924aede3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9360.json
@@ -0,0 +1 @@
+{"null": 0.8065558975991853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9361.json
new file mode 100644
index 00000000000..bb84cc0967b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9361.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9362.json
new file mode 100644
index 00000000000..3c6e799cd9c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9362.json
@@ -0,0 +1 @@
+{"ABATACEPT": 22.84060209695842, "ARAVA": 5.866058952718866, "ENBREL": 17.901769037737374, "null": 1.272301257144388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9363.json
new file mode 100644
index 00000000000..8c89f6aff67
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9363.json
@@ -0,0 +1 @@
+{"null": 0.356816801180343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9364.json
new file mode 100644
index 00000000000..1ecbb7294af
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9364.json
@@ -0,0 +1 @@
+{"XOLAIR": 121.40023571606756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9365.json
new file mode 100644
index 00000000000..45760881123
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9365.json
@@ -0,0 +1 @@
+{"ABATACEPT": 11.481333752274583, "AFINITOR": 6.412191616901577, "ARAVA": 4.670245793891345, "null": 0.6851638957499865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9366.json
new file mode 100644
index 00000000000..c0fadfa7e9f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9366.json
@@ -0,0 +1 @@
+{"AMIKACIN": 6.735529907934369, "ARAVA": 0.7033368145589917, "BEDAQUILINE": 6.258773779897765, "BENLYSTA": 8.128558707938724, "CELLCEPT": 1.2773009499492451, "CIMZIA": 1.1119047967409998, "COMIRNATY": 0.9444852933744204, "FORSTEO": 0.9097804474656368, "HUMIRA": 1.6578921393213844, "KEYTRUDA": 1.9700751881204788, "METHOTREXATE": 3.2399542689657204, "NEXAVAR": 2.0141032359866107, "OLANZAPINE": 0.7838466894446291, "PEGASYS": 2.493331852741769, "PEGINTRON": 2.2881452715823616, "ROACTEMRA": 1.6964588008088897, "SIMPONI": 3.825345506352041, "SPIKEVAX": 0.5245522643076759, "SPRYCEL": 14.550612891694469, "STELARA": 1.689651137019815, "SUTENT": 0.9389541369792668, "TASIGNA": 2.552552778392968, "TOZINAMERAN": 0.9735983518695392, "VAXZEVRIA": 0.3079461376479542, "XELJANZ": 1.419604454528835, "XOLAIR": 1.5797609590171993, "ZOSTAVAX": 0.7036035971151959, "ZYPREXA": 0.7581326697995425, "null": 1.070163519715322}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9367.json
new file mode 100644
index 00000000000..04ddb9d866c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9367.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 4.9786162063403, "AZATHIOPRINE": 4.998206482143334, "BUDESONIDE": 24.893644284213497, "CHAMPIX": 1.294487770199927, "CICLOSPORIN": 1.137835885182365, "COMIRNATY": 1.013513526973313, "NUCALA": 3.850794541975483, "PANTOPRAZOLE": 13.000663835424255, "SPIKEVAX": 1.2730377766725791, "SUTENT": 1.6808446609467922, "TOZINAMERAN": 2.9468304822548657, "VAXZEVRIA": 0.5828266178042862, "null": 0.5894632159898447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9368.json
new file mode 100644
index 00000000000..fc7a2a31280
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9368.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.6994741766457435, "SPIKEVAX": 1.205957441345697, "VAXZEVRIA": 0.2784292898552481, "null": 0.6683978032847203}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9369.json
new file mode 100644
index 00000000000..610040859ef
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9369.json
@@ -0,0 +1 @@
+{"ABILIFY": 11.002662062773094, "OLANZAPINE": 69.57821830741264, "ZYPREXA": 13.29450809415053, "null": 1.9831808351786344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/937.json
index 2350e97a7a3..07b7eee45cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/937.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/937.json
@@ -1 +1 @@
-{"ELIQUIS": 3.259793871613891, "null": 1.0883669204998352}
\ No newline at end of file
+{"null": 2.776536066930761}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9370.json
new file mode 100644
index 00000000000..b5c608265f9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9370.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3742664104455092, "MIRABEGRON": 426.50703372673775, "VAXZEVRIA": 0.3445497534601741, "null": 0.8758643847174595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9371.json
new file mode 100644
index 00000000000..59e9e0ddb5c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9371.json
@@ -0,0 +1 @@
+{"LEVETIRACETAM": 36.04375776367828, "null": 0.9607375764284104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9372.json
new file mode 100644
index 00000000000..f5c69fdf5d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9372.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 113.87109256001396, "AVASTIN": 6.935865425759129, "BUSULFAN": 7.57149453633704, "CABOMETYX": 9.932560880168898, "CELLCEPT": 3.4445512308364505, "CICLOSPORIN": 9.052697245316036, "CYTARABINE": 16.22595817284289, "DOCETAXEL": 5.05545290243944, "IRESSA": 22.450609301793232, "KEYTRUDA": 3.60293607173554, "LENVIMA": 12.528553601031517, "METHOTREXATE": 2.765977707225652, "NEXAVAR": 4.561519399465767, "SUTENT": 2.083110608442775, "null": 1.1015374731627954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9373.json
new file mode 100644
index 00000000000..2a6fda28917
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9373.json
@@ -0,0 +1 @@
+{"BYETTA": 96.8829292325847, "JANUMET": 171.56728376633947, "JANUVIA": 67.64771204508088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9374.json
new file mode 100644
index 00000000000..098c3174830
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9374.json
@@ -0,0 +1 @@
+{"null": 3.704327572966921}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9375.json
new file mode 100644
index 00000000000..5482613ce84
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9375.json
@@ -0,0 +1 @@
+{"null": 0.4065230150002053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9376.json
new file mode 100644
index 00000000000..558aed6150f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9376.json
@@ -0,0 +1 @@
+{"BETAFERON": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9377.json
new file mode 100644
index 00000000000..930398aeb2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9377.json
@@ -0,0 +1 @@
+{"null": 0.6800957629311455}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9378.json
new file mode 100644
index 00000000000..460de40fcd3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9378.json
@@ -0,0 +1 @@
+{"CELLCEPT": 14.73818944609044, "PEGASYS": 3.7472211405682647, "null": 0.5648600523200555}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9379.json
new file mode 100644
index 00000000000..98be2c69087
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9379.json
@@ -0,0 +1 @@
+{"null": 3.9109356712706345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/938.json
index 1843a71dc3e..576481ba95f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/938.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/938.json
@@ -1 +1 @@
-{"KETOCONAZOLE": 199.8597747404807, "TOVIAZ": 41.391904487724005, "ZYPREXA": 4.166996749933885, "null": 2.4644238263318696}
\ No newline at end of file
+{"COMIRNATY": 5.683954618085744, "SPIKEVAX": 2.4071832046584767, "VAXZEVRIA": 0.9369272954648858}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9380.json
new file mode 100644
index 00000000000..2d190af1abb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9380.json
@@ -0,0 +1 @@
+{"ABACAVIR": 7.609767410855049, "CASPOFUNGIN": 53.62121961048446, "CELLCEPT": 22.712701130260477, "CICLOSPORIN": 10.40936798120863, "CYTARABINE": 14.945647142137853, "TEMODAL": 54.99866947203114, "null": 0.2151003717756724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9381.json
new file mode 100644
index 00000000000..3084c093058
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9381.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.3495821354321105, "ACTRAPID": 11.995337305180469, "ADCETRIS": 36.70440870977886, "AFINITOR": 6.639361088191408, "ALEMTUZUMAB": 10.567714786104702, "ALIMTA": 1.3836629391087565, "ARAVA": 0.2714315622317892, "ASPARAGINASE": 2.80990899806932, "ATAZANAVIR": 3.2413950833732352, "AVASTIN": 1.110149443660523, "AZACITIDINE": 4.810503632835713, "AZATHIOPRINE": 4.924344327145331, "BASILIXIMAB": 29.856816599360705, "BENLYSTA": 1.421154286092055, "BEVACIZUMAB": 3.230219643851472, "BIKTARVY": 6.084671348336378, "BLINCYTO": 36.114422173161934, "BUDESONIDE": 0.6227053709672017, "BUSULFAN": 8.024730618495976, "CARMUSTINE": 20.318614157098374, "CELLCEPT": 17.82353210971254, "CICLOSPORIN": 8.906919428307452, "CIMZIA": 1.0980178273179872, "COMBIVIR": 4.627442006135585, "COMIRNATY": 0.0117638971878455, "COSENTYX": 0.6559572947107691, "CYTARABINE": 4.394982201765128, "DARATUMUMAB": 34.459013345949, "DARUNAVIR": 26.9176148350109, "DARZALEX": 3.164763672908086, "DESCOVY": 10.607492205056912, "DEXAMETHASONE": 8.146510944844623, "DOCETAXEL": 2.569518615565977, "DOXORUBICIN": 16.595479193898992, "EMTRICITABINE": 8.01648309077969, "EPIVIR": 9.083205861262153, "GANCICLOVIR": 17.951250688834016, "HALAVEN": 4.413919403031031, "HERCEPTIN": 2.172956973179268, "HUMIRA": 1.00597171627323, "IBRANCE": 0.5012817246058141, "INFLIXIMAB": 4.5489797844148745, "IPILIMUMAB": 2.082410976904716, "IRESSA": 1.855735911667845, "ISENTRESS": 9.493460535813176, "JAKAVI": 5.175698408417468, "KALETRA": 4.441955334920688, "KEYTRUDA": 4.05608732474853, "LAMIVUDINE": 4.145989802783515, "LEVOFLOXACIN": 2.0926051730514024, "LYNPARZA": 3.961157915100298, "MABTHERA": 44.47282078568343, "MERCAPTOPURINE": 5.66493198243213, "METHOTREXATE": 13.379041875491554, "MYCOPHENOLATE": 13.072287889091877, "NEXAVAR": 0.572836753046272, "OPDIVO": 3.897909439326853, "PEMBROLIZUMAB": 2.3489207356030346, "RAPAMUNE": 7.110986410048895, "REMICADE": 12.211236564333936, "RINVOQ": 9.259363737595075, "RITUXIMAB": 33.174023641582735, "ROACTEMRA": 4.352298166447323, "SIMPONI": 7.1019196961787605, "SOLIRIS": 0.7874448015508252, "STELARA": 0.4805596335425862, "TAGRISSO": 2.552700740824178, "TEMODAL": 30.49218608333081, "TEMOZOLOMIDE": 17.669069548919932, "TIVICAY": 7.291528400449626, "TORISEL": 23.487759819321926, "XELJANZ": 1.513337421345599, "ZIAGEN": 10.561805036617551, "null": 0.4998284910138175}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9382.json
new file mode 100644
index 00000000000..502cf0b10ed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9382.json
@@ -0,0 +1 @@
+{"BIKTARVY": 19.300673001841798, "CICLOSPORIN": 9.745118438292131, "COMIRNATY": 0.0959005565497084, "COSENTYX": 5.401714969116686, "DEXAMETHASONE": 13.10319058319103, "FENTANYL": 4.8086192901379565, "OFEV": 12.962014744564977, "null": 1.1161603446939088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9383.json
new file mode 100644
index 00000000000..44acc6cc724
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9383.json
@@ -0,0 +1 @@
+{"AMINOSALICYLIC": 49.00196345517049, "TRELEGY": 99.34140171115962, "null": 1.9034118840965917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9384.json
new file mode 100644
index 00000000000..bbbc3038483
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9384.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.3079672135313304, "ABATACEPT": 0.6567773686121584, "ABILIFY": 0.3520829871809605, "ABRAXANE": 1.5590106865518534, "ACLASTA": 0.8808550669447622, "ACLIDINIUM": 4.887498549939374, "ACTOS": 1.0518182882911693, "ADALIMUMAB": 0.6478258204399361, "ADCETRIS": 2.0239026324312097, "ADCIRCA": 1.698857552953501, "ADEMPAS": 1.9206110088508304, "ADVAGRAF": 0.8263804209871624, "AERIUS": 0.2837324696195568, "AFINITOR": 2.4805128262559086, "AFLIBERCEPT": 1.0029427327644809, "AIMOVIG": 0.5414312242298046, "ALEMTUZUMAB": 1.1666357720022982, "ALIMTA": 1.8705082750012827, "ALISKIREN": 0.224137100133015, "ALL": 1.0865879308528157, "ALPELISIB": 0.5139811953771274, "AMBRISENTAN": 1.6189208796578758, "AMIKACIN": 1.5964002973995797, "AMINOSALICYLIC": 0.2921785850830947, "ANAKINRA": 0.2501848308858054, "ANIDULAFUNGIN": 1.0314344443041188, "ANORO": 3.6853610342420335, "ANTIBIOTICS": 2.4517125532394286, "APIDRA": 0.543900480124907, "APIXABAN": 0.2932032727365395, "APREMILAST": 0.3357790369384342, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9385.json
new file mode 100644
index 00000000000..d5a67cfabc3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9385.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 328.10740233072767}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9386.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9386.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9387.json
new file mode 100644
index 00000000000..5e32d29f223
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9387.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9388.json
new file mode 100644
index 00000000000..874430ba5cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9388.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 0.2324331057964955, "ADCIRCA": 9.63258671527971, "AFINITOR": 2.5476266220056845, "ALIMTA": 2.7835395416865327, "BASILIXIMAB": 10.052655217649246, "BORTEZOMIB": 8.285454616131386, "BUSULFAN": 4.192279288135008, "CABOMETYX": 3.593742789696394, "CANCIDAS": 6.20480848018251, "CASPOFUNGIN": 8.66790693928, "CELLCEPT": 3.966039048730335, "CICLOSPORIN": 5.550545579035877, "CIMZIA": 1.3692486138102689, "COMIRNATY": 0.1556861395902123, "COSENTYX": 0.7958101577765444, "CYTARABINE": 1.59010991488703, "DEXAMETHASONE": 4.137726436020023, "DOXORUBICIN": 4.575871899759484, "ELIQUIS": 0.5904549515592192, "FASENRA": 3.668710854515532, "GANCICLOVIR": 5.285561322354974, "IBRANCE": 0.8077727184233678, "IRESSA": 10.327780174809508, "JAKAVI": 1.9318369860701732, "JEVTANA": 16.179885360866663, "KEYTRUDA": 9.302766115684337, "LEVOFLOXACIN": 1.4992284007334948, "METHOTREXATE": 4.770754973417148, "MICARDIS": 4.173568235739093, "MYCOPHENOLATE": 6.415445726270518, "NUCALA": 2.4555279989246537, "OMALIZUMAB": 1.8464330628344767, "OPDIVO": 7.333087599237727, "OPSUMIT": 1.4975603877472925, "PEGASYS": 0.9661156877159176, "PEGINTRON": 0.9559617119009542, "PLAVIX": 0.5438417901290803, "REMDESIVIR": 18.068060823118877, "RINVOQ": 3.8008173629931736, "RITUXIMAB": 3.737453870178405, "SIMPONI": 5.371408889403349, "SPIKEVAX": 0.2170989168234122, "SPINRAZA": 5.863496938056331, "STELARA": 1.02204301398035, "SUTENT": 0.6871667296279633, "SYNAGIS": 3.4167918356732008, "TAGRISSO": 8.470957817758496, "TAMIFLU": 6.48537805099744, "TOZINAMERAN": 0.1289062652692008, "TRACLEER": 1.6652281670352764, "TRELEGY": 4.493209946447538, "TREMFYA": 5.597575432780567, "VAXZEVRIA": 0.0489207533414419, "VEKLURY": 25.55400714331598, "VFEND": 6.087437432974514, "XELJANZ": 2.169862894130245, "ZOSTAVAX": 0.7140776414960573, "null": 0.7148098550571377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9389.json
new file mode 100644
index 00000000000..bec0750bb82
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9389.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/939.json
index af63fe6a24c..420da0e9e3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/939.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/939.json
@@ -1 +1 @@
-{"SPIKEVAX": 1.1056641219791492, "null": 1.280602668235468}
\ No newline at end of file
+{"null": 4.55082689185402}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9390.json
new file mode 100644
index 00000000000..3113e3f0bdf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9390.json
@@ -0,0 +1 @@
+{"null": 0.4588045923273245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9391.json
new file mode 100644
index 00000000000..c6dd8b40619
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9391.json
@@ -0,0 +1 @@
+{"ARAVA": 2.830312972961501, "CELLCEPT": 45.08290222041252, "null": 0.4290911428678813}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9392.json
new file mode 100644
index 00000000000..7609a08e8c7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9392.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 65.7852598678072, "ARAVA": 0.5043879446609332, "AZATHIOPRINE": 14.63297826772154, "BUSULFAN": 48.73794823736795, "CELLCEPT": 22.247557188205835, "CICLOSPORIN": 33.670284412725714, "CYTARABINE": 11.1639430085824, "DEXAMETHASONE": 5.909794204954746, "GANCICLOVIR": 96.60966432325596, "METHOTREXATE": 4.280609336018784, "MYCOPHENOLATE": 45.275112236602936, "RITUXIMAB": 6.436039848177806, "THIOTEPA": 65.051301155106, "null": 0.47657911204624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9393.json
new file mode 100644
index 00000000000..f4a3cc97b26
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9393.json
@@ -0,0 +1 @@
+{"null": 0.407070785761184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9394.json
new file mode 100644
index 00000000000..857bbda3795
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9394.json
@@ -0,0 +1 @@
+{"ASPARAGINASE": 17.05388200448535, "AZACITIDINE": 52.381814793976176, "BUSULFAN": 23.117796142516063, "CARFILZOMIB": 15.851280353513491, "CELLCEPT": 7.2647681602303535, "CICLOSPORIN": 9.20597220177673, "CYTARABINE": 24.842092675096893, "DEXAMETHASONE": 7.689982449007844, "GANCICLOVIR": 19.1127906397976, "ICLUSIG": 11.280808610512429, "JAKAVI": 3.013734966686728, "KYMRIAH": 7.032640355274652, "LEVOFLOXACIN": 3.2040512123830585, "MELPHALAN": 27.487919385052948, "METHOTREXATE": 4.119438752789595, "NOXAFIL": 53.83966995819555, "POSACONAZOLE": 48.1700031930461, "RITUXIMAB": 4.6095371833263545, "SIMPONI": 1.763731269141989, "SOLIRIS": 2.915137879511847, "SPRYCEL": 4.46817887476219, "STELARA": 1.1070906041622288, "TRELEGY": 4.619843761778647, "VENETOCLAX": 21.67345627342415, "VFEND": 39.69545904632764, "VORICONAZOLE": 16.482551629034095, "VYXEOS": 91.18708181728309, "XELJANZ": 2.6587647413765243, "null": 0.546426995630485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9395.json
new file mode 100644
index 00000000000..2a0f6893ed7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9395.json
@@ -0,0 +1 @@
+{"null": 0.210060546647814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9396.json
new file mode 100644
index 00000000000..5d1a7d38f65
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9396.json
@@ -0,0 +1 @@
+{"VEDOLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9397.json
new file mode 100644
index 00000000000..559a3f8b858
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9397.json
@@ -0,0 +1 @@
+{"TAMIFLU": 109.02266483115554, "null": 0.4889002871726337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9398.json
new file mode 100644
index 00000000000..177aa7bed54
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9398.json
@@ -0,0 +1 @@
+{"BUSULFAN": 21.1292913803044, "CELLCEPT": 6.13989666463586, "CICLOSPORIN": 5.125352396748856, "CYTARABINE": 9.477767992865791, "DEXAMETHASONE": 8.663538139750413, "FENTANYL": 4.225567377096887, "JANUMET": 7.13631619259466, "SOLIRIS": 8.782564074549969, "null": 0.6207363255876047}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9399.json
new file mode 100644
index 00000000000..a576d7f2ad6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9399.json
@@ -0,0 +1 @@
+{"CELLCEPT": 7.915553703535701, "CICLOSPORIN": 5.754349225312346, "CIMZIA": 6.975598641932013, "SIMPONI": 8.575987738904857, "STELARA": 5.582575628677176, "null": 0.5410730852689841}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/94.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/94.json
index 14ed45c4411..31bd683451e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/94.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/94.json
@@ -1 +1 @@
-{"AFINITOR": 3.125891664429479, "AIMOVIG": 1.3449257634568954, "AUBAGIO": 1.841387434947751, "AVASTIN": 1.103852612066428, "BELIMUMAB": 4.987092114352351, "BENLYSTA": 1.3283335045602211, "BRAFTOVI": 3.6249476135339824, "BRINTELLIX": 3.3150926413451027, "CABOMETYX": 1.0657263838686053, "CAPRELSA": 27.746559207382862, "CARIPRAZINE": 18.9497138153202, "CELLCEPT": 3.01348220504698, "CHAMPIX": 1.3552444324545447, "COAPROVEL": 1.5628225091226755, "COSENTYX": 2.2428569208046785, "COTELLIC": 3.555496705658454, "DACLIZUMAB": 136.8127877847876, "DASATINIB": 6.5464473532426135, "DULOXETINE": 1.4818236066003208, "ELLAONE": 8.076129688567814, "ENTYVIO": 4.775239499533394, "ERBITUX": 2.614319999142741, "ESMYA": 5.843786208510593, "ESOMEPRAZOLE": 1.918750402031256, "EVRA": 3.0727292852334545, "FAMPYRA": 1.3831649949894038, "GARDASIL": 4.271315468787484, "GENVOYA": 3.6600306136655134, "HERCEPTIN": 1.8719141266086656, "HUMIRA": 3.072057412892482, "INCIVO": 1.5207335678441416, "INFLIXIMAB": 3.6345063142172536, "IRESSA": 8.154198755526084, "KAFTRIO": 26.78271859512774, "KALYDECO": 4.158813117213652, "KEPPRA": 1.380606240270264, "KESIMPTA": 3.275654601448426, "LEFLUNOMIDE": 3.6720547016425527, "MAVENCLAD": 2.635085311351826, "MEKINIST": 3.865636637777612, "METHOTREXATE": 1.1090706303341298, "NEXAVAR": 1.0836935422159812, "OMALIZUMAB": 1.8277104451452213, "RAPAMUNE": 2.4842823850667592, "RELVAR": 1.3839320400628905, "RINVOQ": 49.621101479197925, "SHINGRIX": 1.0026787034345876, "SKYRIZI": 2.9781726311055223, "SOMATROPIN": 3.2689167459726987, "SPRYCEL": 2.8943809398626428, "STELARA": 2.3471767851152108, "SUTENT": 1.5153447974921592, "TAGRISSO": 3.9817893001292526, "TASIGNA": 1.1210726445067232, "TESTOSTERONE": 9.482122962005262, "TREMFYA": 1.4035297640781286, "UPADACITINIB": 118.97330193862942, "VECTIBIX": 7.180639476509835, "XELJANZ": 4.823237463049578, "XOLAIR": 1.0326433266366208, "ZELBORAF": 5.960635758626046, "null": 1.1962985124730867}
\ No newline at end of file
+{"MELATONIN": 233.1352449824683, "null": 0.2977256987536396}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/940.json
index 8c78b1d8671..109ef79acb1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/940.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/940.json
@@ -1 +1 @@
-{"APIDRA": 2.336487484794882, "AUBAGIO": 17.78301195745669, "CLOPIDOGREL": 2.5365319088348848, "CRIXIVAN": 8.516030846607116, "ELIQUIS": 1.5630572181278388, "EXFORGE": 2.28905656664189, "FAMPYRA": 23.549927721857088, "FENTANYL": 1.1388730030078262, "GARDASIL": 1.4274411806183398, "HUMALOG": 1.668379278924605, "IBRANCE": 1.4725913779126434, "INSULIN": 2.5526580182815954, "JANUVIA": 6.997635377179516, "JARDIANCE": 1.6163781119220249, "KEPPRA": 1.085281320683521, "LANTUS": 1.3753076566948228, "LEMTRADA": 3.2882341622141644, "LYRICA": 2.59103728976664, "SIMPONI": 1.1371514901032636, "SUBOXONE": 1.3338764031763668, "TOVIAZ": 25.227542981438216, "TRELEGY": 3.568153805319373, "XTANDI": 2.411278278563966, "ZOSTAVAX": 3.158742490371856, "ZYPREXA": 1.287215997675444, "null": 1.6167675098816867}
\ No newline at end of file
+{"null": 0.8215158129056229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9400.json
new file mode 100644
index 00000000000..bf0c6a243ba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9400.json
@@ -0,0 +1 @@
+{"ANAKINRA": 107.6523676112656, "GANCICLOVIR": 261.0318101212616, "null": 1.205592121999235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9401.json
new file mode 100644
index 00000000000..1002ee993c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9401.json
@@ -0,0 +1 @@
+{"null": 1.6079139675165732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9402.json
new file mode 100644
index 00000000000..6676a863216
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9402.json
@@ -0,0 +1 @@
+{"CYTARABINE": 20.861977227008, "GANCICLOVIR": 138.39174146074512, "null": 0.9047325736363416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9403.json
new file mode 100644
index 00000000000..5129eddaded
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9403.json
@@ -0,0 +1 @@
+{"CELLCEPT": 11.64158435404511, "COMIRNATY": 0.1325712028253103, "METHOTREXATE": 4.956236872611846, "PEGASYS": 2.442649027553118, "ROACTEMRA": 13.88937290433322, "STELARA": 3.01758045622634, "null": 0.6886010239531393}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9404.json
new file mode 100644
index 00000000000..3f37b48c8b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9404.json
@@ -0,0 +1 @@
+{"KYPROLIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9405.json
new file mode 100644
index 00000000000..ccb3d409962
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9405.json
@@ -0,0 +1 @@
+{"CELLCEPT": 6.1560648912048, "CICLOSPORIN": 8.410939799070904, "KEPPRA": 4.458221696507135, "ORKAMBI": 37.72375508149661, "TOBRAMYCIN": 53.40531967015604, "null": 0.7089545508750368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9406.json
new file mode 100644
index 00000000000..8876fcc00d2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9406.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 28.06591156675037, "MEPOLIZUMAB": 30.197184288475004, "SPINRAZA": 60.99532952499428, "SYNAGIS": 607.4683976830942, "null": 0.3690732321730425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9407.json
new file mode 100644
index 00000000000..2064ce7a943
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9407.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 2.5886348596967266, "KEPPRA": 3.930628655147174, "KEYTRUDA": 1.6330751673702704, "ORKAMBI": 34.55838598085397, "PEGASYS": 2.957090187807436, "PEGINTRON": 4.110125124260783, "PRIVIGEN": 23.696515497988905, "null": 1.0561156339439448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9408.json
new file mode 100644
index 00000000000..ece610e6d12
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9408.json
@@ -0,0 +1 @@
+{"BIKTARVY": 45.13149165628347, "CANAKINUMAB": 1284.7406007768789, "PEGASYS": 7.061844426530764, "null": 0.7369598637620881}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9409.json
new file mode 100644
index 00000000000..cb6bf1a4722
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9409.json
@@ -0,0 +1 @@
+{"ARAVA": 2.528489176556317, "BENLYSTA": 4.156583469456789, "BUDESONIDE": 5.515432395073896, "CELLCEPT": 3.566068220181602, "CICLOSPORIN": 5.052725273166687, "COBIMETINIB": 51.45739142043528, "COMIRNATY": 0.1148791107387941, "CYTARABINE": 4.427158217358356, "ENBREL": 6.367338702120551, "RITUXIMAB": 4.357631341478373, "SPIKEVAX": 0.3255977348251231, "SPINRAZA": 25.57541487592364, "SYNAGIS": 25.409601766476616, "TAMIFLU": 4.256901990761142, "TRACLEER": 3.654001643077791, "VAXZEVRIA": 0.2659918194102139, "XELJANZ": 1.5727470551047502, "null": 0.6515748201756595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/941.json
index f14c827f1a0..4cca67a6101 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/941.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/941.json
@@ -1 +1 @@
-{"AUBAGIO": 10.47895268023601, "VAXZEVRIA": 1.1326392560888767, "null": 1.028917728819186}
\ No newline at end of file
+{"null": 2.560571341029489}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9410.json
new file mode 100644
index 00000000000..3e6ee2ba9aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9410.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.2806367408961092, "ABRAXANE": 10.89664039951243, "ADCETRIS": 6.90516272421026, "AFINITOR": 32.9257125893692, "ALEMTUZUMAB": 5.187660126441732, "ALIMTA": 16.13262891593914, "ARAVA": 0.4891036162548864, "ATEZOLIZUMAB": 11.95312957917767, "AUBAGIO": 0.2897776109002087, "AVASTIN": 1.1432069973102987, "AVELUMAB": 8.365874232351949, "AXITINIB": 5.799894223368479, "AZACITIDINE": 4.512906102551736, "BENLYSTA": 0.3867958476276718, "BENRALIZUMAB": 5.0932010724753685, "BEVACIZUMAB": 3.052696793955981, "BORTEZOMIB": 1.1746478228254822, "BRAFTOVI": 1.199717761795452, "BUSULFAN": 4.5497526230654906, "CABOMETYX": 1.5711832460998307, "CAELYX": 2.416346374017764, "CAPECITABINE": 3.534368708248067, "CARMUSTINE": 8.776898531720585, "CELLCEPT": 0.9412103899224644, "CICLOSPORIN": 0.907313098594926, "CIMZIA": 0.3855474928146125, "COMIRNATY": 0.1673260572377598, "COSENTYX": 0.1624992835679978, "COTELLIC": 2.678370267489312, "CUBICIN": 6.1574672326928725, "CYTARABINE": 0.8750704920843372, "DABRAFENIB": 8.993253828545377, "DARZALEX": 1.3182252725884318, "DEXAMETHASONE": 1.2791750478327857, "DOCETAXEL": 2.8645296967622027, "DOXORUBICIN": 3.712798630356106, "ELIQUIS": 0.2793339989054062, "ENBREL": 1.3458071552515674, "ENTYVIO": 1.225052194893559, "ESBRIET": 0.5812452427388708, "EVEROLIMUS": 17.09063871947472, "FASENRA": 1.1895956104048662, "FASLODEX": 1.827094398083721, "FILGRASTIM": 4.767284495053123, "FORSTEO": 0.3845613935306229, "FULVESTRANT": 2.8614968034522104, "GANCICLOVIR": 1.5488379855503651, "GARDASIL": 0.1134060939161271, "GEFITINIB": 4.128659506926195, "HALAVEN": 5.133553341464911, "HERCEPTIN": 4.936085658016009, "HUMALOG": 0.2162416388614347, "HUMIRA": 0.6837747903402265, "IBRANCE": 2.467972712288859, "ICLUSIG": 1.349999792300572, "IMFINZI": 20.84180021060519, "INCIVO": 1.071897995841716, "INFLIXIMAB": 4.943794564730101, "INLYTA": 1.0955938448140523, "IPILIMUMAB": 28.607869287609, "IRESSA": 6.517559829522712, "JAKAVI": 2.094469014569613, "JANUMET": 0.6411550842011912, "JEVTANA": 1.6809710133966524, "KEYTRUDA": 23.00530411361578, "KISQALI": 10.406482214027596, "KYPROLIS": 4.666072869667799, "LANTUS": 0.0884089378775162, "LEFLUNOMIDE": 2.2873135855192306, "LEMTRADA": 3.7566032571996937, "LEVETIRACETAM": 0.5819190904788809, "LEVOFLOXACIN": 0.9949467997094176, "LIBTAYO": 22.17963797527833, "LYNPARZA": 4.9431038216057335, "MABTHERA": 5.992381102178824, "MEKINIST": 3.778139555715681, "MEPOLIZUMAB": 0.5294849734694492, "METHOTREXATE": 2.62141569605558, "MIDAZOLAM": 1.7712742383858595, "MULTAQ": 1.5972970582705368, "MYCOPHENOLATE": 1.2763862968653488, "NEULASTA": 1.8758599873034696, "NEXAVAR": 0.3643212037178895, "NIVOLUMAB": 12.589674995197182, "NUCALA": 0.6705935871530244, "OFEV": 0.772175722752686, "OLANZAPINE": 0.1817792016411918, "OLAPARIB": 6.5722731535846455, "OMALIZUMAB": 0.3852900565799062, "OPDIVO": 22.54156935062784, "OPSUMIT": 0.5525801604855388, "OSIMERTINIB": 53.44695903828789, "PACLITAXEL": 6.586848759406368, "PEGASYS": 0.6574082165455, "PEGINTRON": 1.3944145400273629, "PEMBROLIZUMAB": 30.103912837156034, "PEMETREXED": 7.623794091325042, "PLAVIX": 0.1593606612940155, "PREGABALIN": 1.5411742517999316, "RAPAMUNE": 20.92926916770092, "RIBAVIRIN": 0.5851953211466396, "RIBOCICLIB": 4.221716719579039, "RINVOQ": 0.9817461690362644, "RITUXIMAB": 1.2878171819116777, "ROACTEMRA": 1.7801569078614887, "SIMPONI": 0.5176762403223208, "SPIKEVAX": 0.1453512904159415, "SPRYCEL": 1.801015441532781, "STELARA": 0.81524887235348, "STIVARGA": 0.6556484841643729, "SUTENT": 0.5184094700508793, "TAGRISSO": 41.91260667605256, "TAMIFLU": 0.8355254417393896, "TAXOTERE": 3.392565185806798, "TEMSIROLIMUS": 26.033960533213502, "THALIDOMIDE": 2.956133445462064, "TICAGRELOR": 1.530717754311274, "TORISEL": 17.297661059169375, "TOZINAMERAN": 0.2144007033244472, "TRELEGY": 1.287787494564752, "TRODELVY": 13.655155478146348, "VAXZEVRIA": 0.0871700883965833, "VELCADE": 5.55748686591266, "VOTRIENT": 0.9348158908411054, "XALKORI": 11.01864522069129, "XELJANZ": 0.4150946967631797, "XOLAIR": 0.3924133621308823, "YERVOY": 7.427405654605455, "ZOSTAVAX": 0.4156201335963072, "null": 0.5731080456849198}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9411.json
new file mode 100644
index 00000000000..13bf18efc69
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9411.json
@@ -0,0 +1 @@
+{"FENTANYL": 7.204105735223896, "KEPPRA": 4.618408448494322, "OLANZAPINE": 9.079364323786155, "null": 2.135795496097223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9412.json
new file mode 100644
index 00000000000..32c8633ad4b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9412.json
@@ -0,0 +1 @@
+{"null": 1.3268813563077655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9413.json
new file mode 100644
index 00000000000..14b9fca22ca
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9413.json
@@ -0,0 +1 @@
+{"null": 0.7437140097535307}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9414.json
new file mode 100644
index 00000000000..7dcccdee885
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9414.json
@@ -0,0 +1 @@
+{"NEXAVAR": 6.331969999942376, "null": 0.9044602366630752}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9415.json
new file mode 100644
index 00000000000..2d3c3742295
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9415.json
@@ -0,0 +1 @@
+{"AFINITOR": 1.6838582494430896, "ALIMTA": 3.910957483134511, "AMINOSALICYLIC": 3.414693284495831, "ARAVA": 0.2331921372369285, "ATRIPLA": 0.1262050775110952, "AVANDIA": 0.4008630863256985, "AVASTIN": 1.971013383025492, "AZACITIDINE": 7.678725651460646, "BEDAQUILINE": 26.054463571380836, "BENLYSTA": 0.7966874072685382, "BEVACIZUMAB": 1.3401154068250396, "BIKTARVY": 2.04675400184223, "BRIDION": 4.495733503763975, "BUDESONIDE": 3.868043987615558, "BUPRENORPHINE": 0.8438527142442189, "BUSULFAN": 2.385592001517738, "CABOMETYX": 2.5671816044202616, "CELLCEPT": 1.059363030450438, "CHOLESTAGEL": 69.075898608453, "CICLOSPORIN": 2.1011931283167007, "CLOPIDOGREL": 0.2927984562349435, "COMIRNATY": 0.152531735353053, "COSENTYX": 0.658203887953424, "CYMBALTA": 0.223940368383734, "CYTARABINE": 1.6065993419179057, "DELAMANID": 6.737830220635362, "DEXAMETHASONE": 3.782498722315861, "DOCETAXEL": 1.762018611898193, "ELIQUIS": 0.9275906645271778, "ENBREL": 0.3834071630367661, "ERBITUX": 5.316058586044711, "ESBRIET": 7.323111164010298, "FASENRA": 1.7914044031786898, "FENTANYL": 3.673792282596265, "FIRDAPSE": 5.778507363024353, "FORSTEO": 0.5506033552823888, "GARDASIL": 0.2645060472981684, "HALAVEN": 10.589825367498312, "HIZENTRA": 1.5108090603141604, "HUMALOG": 0.8434445847208412, "IBRANCE": 1.0006670449310724, "INCRUSE": 10.127286651124235, "INLYTA": 3.533393888891544, "IRESSA": 7.775588441863413, "JANUVIA": 0.6373497648278073, "JARDIANCE": 0.5830125992588856, "KAFTRIO": 2.9039915924271176, "KALYDECO": 9.462653878567552, "KEPPRA": 0.3415171721143063, "KEYTRUDA": 4.381437393337777, "LENVIMA": 10.744055730438356, "LEVOFLOXACIN": 0.6751485920977398, "MEKINIST": 1.3294921390563532, "MEPOLIZUMAB": 0.8963658090077442, "METHOTREXATE": 1.2498903766348324, "MIDAZOLAM": 2.816640068208496, "NEULASTA": 1.99038968244762, "NEXAVAR": 0.959866076293959, "NUCALA": 1.2311883289138117, "OFEV": 12.751779894493763, "OPDIVO": 1.0576392437510054, "OPSUMIT": 1.279361094375334, "ORKAMBI": 13.334877501826746, "PAZOPANIB": 32.419494668662544, "PEGASYS": 0.6091312194727723, "PEGINTRON": 0.8909760521986989, "PEMBROLIZUMAB": 2.0161010317528567, "PEMETREXED": 2.871185898940192, "PLAVIX": 0.4069029287240667, "REMDESIVIR": 7.598458995946239, "REVATIO": 1.4633842016111245, "RITUXIMAB": 0.9338652250673984, "ROACTEMRA": 1.0267090208722798, "SIMPONI": 0.900723572428784, "SOLIRIS": 0.7851871472401951, "SPIKEVAX": 0.1150667227407557, "SPINRAZA": 11.107134247403348, "SPRYCEL": 1.8679762319125044, "STELARA": 0.544299244294301, "STIVARGA": 0.9387320237006442, "SUFENTANIL": 3.622375758224646, "SUTENT": 1.094538784551761, "SYNAGIS": 3.628023829160131, "TAGRISSO": 6.265809169077893, "TAMIFLU": 1.6045572203793468, "TOZINAMERAN": 0.2527082533984074, "TRACLEER": 3.285757160738092, "TRELEGY": 8.332092253999074, "VAXZEVRIA": 0.0482759064022371, "VEKLURY": 6.444235188128433, "VFEND": 1.7940228872328907, "VOTRIENT": 21.79921209366731, "XALKORI": 1.9145793858365965, "XELJANZ": 0.5707349526152903, "XOLAIR": 0.80882970158129, "ZOSTAVAX": 0.5182681296301801, "null": 1.1795606569956163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9416.json
new file mode 100644
index 00000000000..d6bced87d94
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9416.json
@@ -0,0 +1 @@
+{"AMINOSALICYLIC": 20.207553212424017, "COMIRNATY": 0.4313594898508255, "VOTRIENT": 13.39582429963201, "null": 0.8083090068781222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9417.json
new file mode 100644
index 00000000000..d200a60533d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9417.json
@@ -0,0 +1 @@
+{"null": 0.6604911223137445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9418.json
new file mode 100644
index 00000000000..15ae5faf560
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9418.json
@@ -0,0 +1 @@
+{"KEPPRA": 35.77609719554013, "null": 0.9020899132525624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9419.json
new file mode 100644
index 00000000000..d22e5146c45
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9419.json
@@ -0,0 +1 @@
+{"null": 0.3661324814727141}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/942.json
index 10445b6e358..b89b65d8923 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/942.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/942.json
@@ -1 +1 @@
-{"CICLOSPORIN": 10.79089490394596, "TOZINAMERAN": 1.0243281421684347, "null": 1.2567487379513032}
\ No newline at end of file
+{"AMELUZ": 406.4519230286784, "COMIRNATY": 0.3345476327508909, "QUTENZA": 252.8061759506137, "VAXZEVRIA": 1.8264331033230157, "null": 2.11098723699018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9420.json
new file mode 100644
index 00000000000..1db156f3af6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9420.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 1.7414686783375624, "BEDAQUILINE": 2.575154579114072, "BENZODIAZEPINE": 33.52905914479428, "BUPRENORPHINE": 6.87541735748153, "CANNABIDIOL": 9.56235383226558, "CHAMPIX": 0.9654703895934462, "COMIRNATY": 0.0404554278073856, "CYMBALTA": 0.8468516521470704, "DULOXETINE": 5.764017352674314, "ELIQUIS": 0.2318807012384335, "ENTRESTO": 1.170605138870347, "FENTANYL": 2.295195460068311, "IBUPROFEN": 4.946990114197902, "IRBESARTAN": 4.114685025399158, "KEPPRA": 1.471385814324076, "LANTUS": 0.4818598255893719, "LOXAPINE": 64.84474681924394, "LYRICA": 3.083319485331353, "MIDAZOLAM": 6.5471491633835806, "NOT": 3.0863450055831905, "OLANZAPINE": 7.453850389050909, "PANTOPRAZOLE": 2.6686900756250407, "PEGINTRON": 0.8060024709283734, "POPPERS": 59.76871710773202, "PREGABALIN": 9.917735170604828, "SUBOXONE": 0.9053919903145689, "SUTENT": 1.0487503823958555, "TOZINAMERAN": 0.1810945082285267, "VAXZEVRIA": 0.0276075233921977, "ZYPREXA": 1.961448772498716, "null": 4.605074448262569}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9421.json
new file mode 100644
index 00000000000..8d81bd93ae1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9421.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.919948139145589, "ARIPIPRAZOLE": 2.2592281817235875, "BIKTARVY": 3.7420826116033674, "BRINTELLIX": 2.8197664097533965, "BUPRENORPHINE": 1.6778893516822846, "ELIQUIS": 0.7518563225445085, "IBUPROFEN": 3.3126944559816027, "LOXAPINE": 59.6502768504546, "LYRICA": 4.086591611608244, "MELATONIN": 6.505750152874651, "MIDAZOLAM": 8.141953088597667, "OLANZAPINE": 9.653128150946989, "PREGABALIN": 13.677759585299258, "ZYPREXA": 1.6074706606047506, "null": 9.28197950677563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9422.json
new file mode 100644
index 00000000000..142561d85f7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9422.json
@@ -0,0 +1 @@
+{"null": 3.1525519358877845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9423.json
new file mode 100644
index 00000000000..b86aa0dff3d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9423.json
@@ -0,0 +1 @@
+{"null": 0.7775215640317513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9424.json
new file mode 100644
index 00000000000..dfc567e46c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9424.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 1.5296113348748246, "ABILIFY": 0.6912177879014755, "ADALIMUMAB": 0.0716839284869931, "ADEMPAS": 1.867867183906501, "AFINITOR": 0.6031004861162339, "AIMOVIG": 0.2493179420556961, "ALEMTUZUMAB": 0.8481717396695485, "ANORO": 1.6304701140153326, "APIDRA": 1.5013878448490223, "ARAVA": 0.1170487817348028, "ATRIPLA": 1.3371698850585418, "AUBAGIO": 2.0044547888472484, "AZACITIDINE": 1.202115542801805, "BENLYSTA": 0.5971319225008406, "BETMIGA": 14.005895435295397, "BIKTARVY": 0.8302631311888352, "BRAFTOVI": 0.7145626961639855, "BRINTELLIX": 1.303987745714254, "BYDUREON": 0.7585443860716599, "BYETTA": 0.7633892576691245, "CELLCEPT": 0.576337191304361, "CHAMPIX": 2.09095290487465, "CICLOSPORIN": 0.2250995636080701, "CIMZIA": 0.4911786044918147, "CLOPIDOGREL": 0.570166931006162, "COAPROVEL": 2.2241615139773634, "COMBIVIR": 0.8929931312429267, "COMIRNATY": 0.3029730844598442, "COSENTYX": 1.1267485708229934, "CYMBALTA": 1.1190015530971087, "DEXAMETHASONE": 0.4102643147817796, "DULAGLUTIDE": 3.5565773784015, "ELIQUIS": 0.8679940689018775, "EMPAGLIFLOZIN": 12.240661494588526, "ENTACAPONE": 3.1450774877689414, "ENTRESTO": 2.604135152429276, "ENTYVIO": 0.5262645117963701, "ENZALUTAMIDE": 3.50676153575294, "ESBRIET": 0.4770148881796983, "ESOMEPRAZOLE": 0.9132429981121502, "EXFORGE": 3.9922118844832912, "EXJADE": 0.7719053603663304, "FAMPRIDINE": 5.931940916156075, "FAMPYRA": 1.2932533846861194, "FASLODEX": 1.1221625831883475, "FENTANYL": 0.7896952394239283, "FORSTEO": 5.715341974846749, "FORXIGA": 17.70527095782819, "FULVESTRANT": 0.8631197855478897, "GARDASIL": 1.1289505581940191, "HUMALOG": 2.1065207739076603, "IBRANCE": 0.8241010369770363, "IBUPROFEN": 0.7481270882574834, "INCIVO": 0.6113789238626602, "INCRUSE": 2.688744731727493, "INLYTA": 0.7046703222441595, "INSULIN": 0.7852447197085476, "INTELENCE": 12.124317213615468, "INVOKANA": 2.1351278355626984, "IRBESARTAN": 1.2640416172588909, "JANUMET": 1.1328418047602808, "JANUVIA": 0.902831052869245, "JARDIANCE": 25.50691249979072, "KEPPRA": 0.5248831097150228, "KESIMPTA": 1.438343917568162, "KEYTRUDA": 0.3259050602785949, "LANTUS": 2.0079664838588416, "LATUDA": 1.3921008814134674, "LEMTRADA": 0.7765564063030298, "LEVEMIR": 0.5485862680912592, "LEVETIRACETAM": 0.3443932361798467, "LEVOFLOXACIN": 0.4684107678016564, "LYRICA": 0.646593362792208, "MELATONIN": 1.3038340605303478, "METHOTREXATE": 0.3674232041050729, "MICARDIS": 1.6262347165632662, "MIRABEGRON": 8.62787136213413, "MODERNA": 0.3826127677490453, "NUCALA": 0.3841253583957784, "OLANZAPINE": 0.2806260241158095, "OPDIVO": 0.4255010389641878, "OPSUMIT": 0.4764724625991993, "OXYBUTYNIN": 4.921441762447618, "PEGASYS": 0.8453123378800894, "PEGINTRON": 1.991257384529049, "PLAVIX": 0.3482444500270446, "RASILEZ": 1.4837724869764433, "RELVAR": 1.1072959467157668, "REVATIO": 0.7386456181227701, "RINVOQ": 1.603216184254224, "SAXENDA": 0.8418308197329941, "SHINGRIX": 0.4013517946362641, "SILODYX": 14.650789830120049, "SIMPONI": 0.550620178478943, "SPIKEVAX": 0.3915292258473923, "SPRYCEL": 0.4794415977193015, "STELARA": 0.3193207837265652, "STRIBILD": 0.8883839021142497, "SUTENT": 0.5054086364126266, "TASIGNA": 0.7938640382843302, "TOUJEO": 1.0441951760987218, "TOVIAZ": 11.34076737873998, "TOZINAMERAN": 0.5663579958152064, "TRACLEER": 0.3122067445097929, "TRELEGY": 1.725577427609284, "TRULICITY": 0.4595421869266924, "TRUVADA": 1.4092700734269143, "VALSARTAN": 2.174530238033752, "VAXZEVRIA": 0.4536226127387432, "VIAGRA": 1.3198287022768247, "VIREAD": 0.8643279468763364, "XELJANZ": 1.432497990583502, "XTANDI": 3.2310860258787715, "XYREM": 3.122479395364816, "ZOSTAVAX": 1.3025013072896436, "ZYPREXA": 1.4034550359199585, "null": 1.2867819533379488}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9425.json
new file mode 100644
index 00000000000..b55803bbf2f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9425.json
@@ -0,0 +1 @@
+{"ANAKINRA": 38.75033360624703, "COMIRNATY": 0.3054154923898578, "null": 1.7116509783580316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9426.json
new file mode 100644
index 00000000000..4e844a008ce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9426.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.82428106243593, "ADALIMUMAB": 5.724400375663205, "ANAKINRA": 12.420765330333715, "ARAVA": 0.8642827639445075, "BENLYSTA": 2.5309394579676234, "CIMZIA": 2.578086345802173, "CLOPIDOGREL": 2.6503406571405006, "COMIRNATY": 1.0829235234211898, "COMPRESSION": 332.39268654815885, "COSENTYX": 2.813247758216445, "ENBREL": 2.611909613285425, "ENTYVIO": 1.5765368810033842, "FORSTEO": 1.3805316195015824, "GARDASIL": 2.7289772784054187, "HUMIRA": 4.8508585010418095, "IBUPROFEN": 2.2837519670866677, "IPILIMUMAB": 11.23661901865747, "JANUVIA": 1.6272282960306983, "KEYTRUDA": 6.084948471745283, "LEFLUNOMIDE": 8.21102447278744, "METHOTREXATE": 3.1855767273513207, "OPDIVO": 3.054261960266129, "PEGASYS": 1.870967052885377, "PEMBROLIZUMAB": 17.232033861551173, "PLAVIX": 1.348476191851248, "RINVOQ": 3.603096765145468, "SHINGRIX": 1.2341736615549084, "SIMPONI": 2.7915290497234566, "SPIKEVAX": 0.5482647845944009, "STELARA": 1.298721885669216, "TOZINAMERAN": 0.4907874191208338, "TWINRIX": 4.854045359640742, "VAXZEVRIA": 0.2938239809088258, "XELJANZ": 2.854896107238248, "XOLAIR": 1.1078982091895129, "ZOSTAVAX": 1.0676696938133048, "null": 0.5695820848974277}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9427.json
new file mode 100644
index 00000000000..0ca4549f060
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9427.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3114162735149856, "null": 0.5998210129059083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9428.json
new file mode 100644
index 00000000000..53981726204
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9428.json
@@ -0,0 +1 @@
+{"CARMUSTINE": 281.1710476480148, "null": 0.8914085045646701}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9429.json
new file mode 100644
index 00000000000..e8bec2b5dfb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9429.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/943.json
index a64a989cffb..2bc619db8c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/943.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/943.json
@@ -1 +1 @@
-{"null": 1.550517434167808}
\ No newline at end of file
+{"AIMOVIG": 0.1682915135705356, "ALDARA": 20.30630379720485, "AMELUZ": 125.9977490592772, "BETAFERON": 1.536580205019826, "BUPRENORPHINE": 0.4226127387395116, "COMIRNATY": 1.925117392888704, "EVRA": 5.052446358825056, "INHIXA": 5.420470806772504, "KENTERA": 9.697428163479664, "LANTUS": 0.2734186987830387, "MIRVASO": 11.537680285135067, "NEULASTA": 2.804593177942601, "NIMENRIX": 0.3493561514183039, "QUTENZA": 155.60998013993242, "SHINGRIX": 0.3460729769656571, "SIMPONI": 0.1429210101603793, "SPIKEVAX": 1.5916867954234817, "SYNAGIS": 1.0204541287625144, "VAXZEVRIA": 8.283057857211558, "ZYCLARA": 12.67780233131007, "null": 0.5449307651923636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9430.json
new file mode 100644
index 00000000000..f74ce2d6df3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9430.json
@@ -0,0 +1 @@
+{"ADENURIC": 1213.2257357097942}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9431.json
new file mode 100644
index 00000000000..d6c2f487dfc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9431.json
@@ -0,0 +1 @@
+{"APIXABAN": 24.53305229726418, "COMIRNATY": 0.9605942234306932, "GARDASIL": 22.053125387903727, "SPIKEVAX": 0.2465735042964206, "TOZINAMERAN": 2.201333998105263, "VAXZEVRIA": 0.6983477868735871, "null": 0.719019411258606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9432.json
new file mode 100644
index 00000000000..70a016ef15c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9432.json
@@ -0,0 +1 @@
+{"APIXABAN": 940.133571336198, "COMIRNATY": 0.0791319165575413, "ELIQUIS": 10.074062551695368, "ESOMEPRAZOLE": 28.027005435198895, "null": 0.1797067073308129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9433.json
new file mode 100644
index 00000000000..6bda1c951dd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9433.json
@@ -0,0 +1 @@
+{"ARANESP": 3.376360370985568, "AXITINIB": 41.56815822263103, "CICLOSPORIN": 3.2418834580765266, "COMIRNATY": 0.1568798766752285, "COSENTYX": 7.962230153687693, "EMPAGLIFLOZIN": 25.16137389725629, "FORXIGA": 17.651908595360727, "INLYTA": 11.72398820540779, "JARDIANCE": 15.25755426953978, "LENVIMA": 27.482390398199648, "SPIKEVAX": 0.1167385646520019, "SUTENT": 1.0800358948734547, "TESTOSTERONE": 193.6453657717842, "VAXZEVRIA": 0.1443944785811809, "null": 1.211444001328823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9434.json
new file mode 100644
index 00000000000..b34aab983be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9434.json
@@ -0,0 +1 @@
+{"JAKAVI": 152.283281656998, "null": 1.2165869975112051}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9435.json
new file mode 100644
index 00000000000..db3a222bc64
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9435.json
@@ -0,0 +1 @@
+{"COMBIVIR": 95.8083307570583, "KEPPRA": 6.86992108967961, "LEVETIRACETAM": 8.229104630163784, "null": 3.056612333433359}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9436.json
new file mode 100644
index 00000000000..df9936ad8d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9436.json
@@ -0,0 +1 @@
+{"ABILIFY": 1.985686693004126, "AFINITOR": 1.4262901527388694, "APIDRA": 4.649757268670929, "ARAVA": 0.9173706623456168, "CHAMPIX": 2.6919628398941797, "COMIRNATY": 0.2276180052898027, "CYMBALTA": 0.4722981220542271, "CYTARABINE": 1.5777828285434738, "DEXAMETHASONE": 1.1048390995151711, "EMPAGLIFLOZIN": 9.441444816522113, "FORXIGA": 9.489025398317878, "GARDASIL": 1.4087072913388197, "HUMALOG": 1.2190919986352775, "INSULIN": 7.44196568028754, "IRBESARTAN": 5.399581495360236, "JANUMET": 3.556964508173514, "JARDIANCE": 10.493366910036327, "KEYTRUDA": 0.5930251387471291, "LANTUS": 1.6218700945640232, "LATUDA": 9.138487424797011, "OLANZAPINE": 7.21641052696354, "PEGASYS": 0.8845201139780553, "PEGINTRON": 1.0943763548338623, "RIBAVIRIN": 3.9943487712233257, "SPIKEVAX": 0.1395010368563868, "SYCREST": 25.35471915052848, "TOZINAMERAN": 0.1944089138945429, "VAXZEVRIA": 0.2476661033903216, "VIREAD": 4.57582520644142, "ZYPREXA": 25.09898153193511, "null": 1.3835306815027426}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9437.json
new file mode 100644
index 00000000000..fed0d99fbc4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9437.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 26.0718592700784, "null": 1.294615628706115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9438.json
new file mode 100644
index 00000000000..854a231aaba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9438.json
@@ -0,0 +1 @@
+{"null": 0.855331966490197}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9439.json
new file mode 100644
index 00000000000..7a117897466
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9439.json
@@ -0,0 +1 @@
+{"FENTANYL": 6.05913427267442, "KEPPRA": 3.055067305227958, "null": 2.667485731330367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/944.json
index 636b6964775..b04590fbcd6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/944.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/944.json
@@ -1 +1 @@
-{"null": 9.151157299211915}
\ No newline at end of file
+{"null": 11.378001142132838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9440.json
new file mode 100644
index 00000000000..e2db4c9ad66
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9440.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.332399208069337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9441.json
new file mode 100644
index 00000000000..d3712a68382
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9441.json
@@ -0,0 +1 @@
+{"AIMOVIG": 0.1614677396295504, "COMIRNATY": 15.989932298043517, "ELLAONE": 14.503021723401998, "EVRA": 2.3654009776792018, "GARDASIL": 0.0763591465354249, "MODERNA": 4.689739456924431, "SPIKEVAX": 2.8071751561424243, "STELARA": 0.2449500773096809, "TOZINAMERAN": 1.1830205329390562, "VAXZEVRIA": 0.6113918642183723, "null": 0.0383918782741833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9442.json
new file mode 100644
index 00000000000..0b8b5834dc8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9442.json
@@ -0,0 +1 @@
+{"ABACAVIR": 44.75061526696715, "SPIKEVAX": 1.9189295407292828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9443.json
new file mode 100644
index 00000000000..7b5e68536c4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9443.json
@@ -0,0 +1 @@
+{"EPCLUSA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9444.json
new file mode 100644
index 00000000000..8585a4402ed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9444.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4640547753376953, "LEVOFLOXACIN": 24.84699561290264, "TOZINAMERAN": 6.7230923497759845, "VAXZEVRIA": 1.167421577681297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9445.json
new file mode 100644
index 00000000000..a82093ea82a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9445.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.567359564621224, "null": 0.9559290879659368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9446.json
new file mode 100644
index 00000000000..21902396111
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9446.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6940597778015541, "null": 0.9309637469000248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9447.json
new file mode 100644
index 00000000000..ec1e2658abe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9447.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.936925997596908, "EFAVIRENZ": 5.425744246544911, "ELIQUIS": 0.3354277616880078, "EVENITY": 3.645073409048223, "FORSTEO": 0.7194296870320266, "IPILIMUMAB": 4.715348616344248, "KEYTRUDA": 6.8237841610258725, "LANTUS": 0.3820434382461029, "MEPOLIZUMAB": 2.6449115508307184, "MODERNA": 2.793531682255277, "NUCALA": 1.792424161271833, "OPDIVO": 7.063942355122454, "PEGASYS": 0.4338332697255917, "PEMBROLIZUMAB": 13.49310077332168, "SHINGRIX": 5.153914517344019, "SPIKEVAX": 1.456931583297855, "STELARA": 1.043849142188963, "TOZINAMERAN": 2.61180083887474, "VAXZEVRIA": 1.015497830449567, "XOLAIR": 0.890786417451019, "ZOSTAVAX": 6.884686416532372, "null": 0.2164892990323837}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9448.json
new file mode 100644
index 00000000000..3fab8a3f96c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9448.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 2.7533415964996832, "COMIRNATY": 0.3388464046949851, "GARDASIL": 2.072305104696043, "IPILIMUMAB": 11.325017009955308, "KEYTRUDA": 8.695178745054756, "OPDIVO": 9.135383838466224, "PEGASYS": 6.100394054249318, "PEGINTRON": 4.003886628389784, "RITUXIMAB": 8.936166895953438, "SPIKEVAX": 0.27702227355533, "TOZINAMERAN": 0.7032296422945491, "VAXZEVRIA": 0.2494590304867894, "null": 1.0008510858604898}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9449.json
new file mode 100644
index 00000000000..5f848be5c14
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9449.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.8661811525432247, "ADCETRIS": 8.777759897138928, "ALIMTA": 1.400944703418, "ARAVA": 0.8106258637118184, "ASPARAGINASE": 1.473805232645462, "ATRIPLA": 0.0924315713441481, "AUBAGIO": 6.214146362741984, "AVAMYS": 1.128811995052569, "AVASTIN": 2.154051222114548, "BEDAQUILINE": 3.245713850429476, "BEVACIZUMAB": 3.30116841447219, "BORTEZOMIB": 25.32014122752416, "BRAFTOVI": 2.93020532691351, "BUSULFAN": 1.2856042251248612, "CAELYX": 4.035874746464884, "CAPECITABINE": 5.2549336965533, "CARFILZOMIB": 4.586160675794254, "CELLCEPT": 1.8246858989055457, "CETUXIMAB": 11.867715054267329, "CHAMPIX": 0.3459043227214318, "CICLOSPORIN": 0.6472690533078649, "COMIRNATY": 0.9109098416390352, "COSENTYX": 0.4876258028687631, "CYMBALTA": 0.1733613328113365, "CYTARABINE": 1.3913158068629603, "DABRAFENIB": 4.975738969265043, "DARZALEX": 13.136839810009102, "DELAMANID": 4.708063363811717, "DEXAMETHASONE": 3.4062211855965496, "DOCETAXEL": 8.979708297874323, "DOLUTEGRAVIR": 27.501523657553747, "ELIQUIS": 0.232924842864605, "ENTYVIO": 0.6633654037852261, "FASENRA": 2.123494882678481, "FENTANYL": 1.1460598750450002, "FORSTEO": 0.4769114578746058, "GARDASIL": 1.302949521010892, "HALAVEN": 11.215632563580252, "HERCEPTIN": 3.995612132084032, "HUMALOG": 0.3560082310481968, "HUMIRA": 0.8344882537663622, "INSULIN": 1.2642024916562948, "IPILIMUMAB": 5.290614128625591, "IRINOTECAN": 4.643550002998962, "JAKAVI": 1.6903293782815696, "KEPPRA": 0.7700558389551498, "KEYTRUDA": 1.1760522915630307, "LAMIVUDINE": 2.8258993565133608, "LANTUS": 0.2876093695224165, "LEFLUNOMIDE": 2.535098900975438, "LEVOFLOXACIN": 1.8974527350466568, "LYNPARZA": 1.5542955168041328, "LYRICA": 0.5573989049172189, "MABTHERA": 7.078936670215466, "MEKINIST": 2.3500422255022744, "MULTAQ": 2.378831802044324, "NEXAVAR": 0.4751865606670045, "NORVIR": 5.739199544723217, "NOXAFIL": 2.94554929983637, "OPDIVO": 1.3773379752262325, "PACLITAXEL": 4.577187379605625, "PANITUMUMAB": 17.62130888824201, "PEGASYS": 1.2215917022518696, "PEGINTRON": 1.2963892279045637, "PEMBROLIZUMAB": 1.7461489551017466, "REYATAZ": 6.777430396939882, "RITUXIMAB": 1.5333918663083683, "ROACTEMRA": 1.0823136677116842, "SHINGRIX": 1.5031215405289629, "SIMPONI": 1.270009489077394, "SPIKEVAX": 0.4652820519540837, "SPRYCEL": 0.8227686150997319, "STELARA": 0.545571983672576, "SUTENT": 0.2819300731388986, "TASIGNA": 1.0552372654763456, "THALIDOMIDE": 23.35385164384917, "TOZINAMERAN": 0.2187501954092951, "TRUVADA": 0.2386910295030141, "TWINRIX": 4.828480778267172, "VAXZEVRIA": 0.3746289692498267, "VECTIBIX": 16.7667016003144, "VFEND": 1.3544065922229562, "VORICONAZOLE": 3.3405895687499347, "VOTRIENT": 0.5062089901782749, "XELJANZ": 0.2607296807246559, "XELODA": 3.27974274011786, "XOLAIR": 0.6052571632866534, "ZERIT": 58.4463593594333, "ZOSTAVAX": 2.0632647804063224, "ZYPREXA": 0.7470006279790323, "null": 0.9957578202589432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/945.json
index 7373e59d04a..284f214c935 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/945.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/945.json
@@ -1 +1 @@
-{"ADCIRCA": 214.99198798090544, "ELIQUIS": 6.876427731048126, "JARDIANCE": 7.439349566077374, "PLAVIX": 5.681022915342981, "STELARA": 5.8638801915177385}
\ No newline at end of file
+{"COMIRNATY": 0.2575541647159637, "QUTENZA": 85.15413995213785, "VAXZEVRIA": 0.2703438513414283, "null": 9.826957533133085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9450.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9450.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9451.json
new file mode 100644
index 00000000000..1889af8c8a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9451.json
@@ -0,0 +1 @@
+{"null": 0.6407477151697535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9452.json
new file mode 100644
index 00000000000..ead8725c17e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9452.json
@@ -0,0 +1 @@
+{"null": 0.6805743670107615}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9453.json
new file mode 100644
index 00000000000..2484a07e72e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9453.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 136.39894313703408, "BUSULFAN": 241.3264522703969, "CICLOSPORIN": 76.9148108909434, "MYCOPHENOLATE": 50.36090592134553}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9454.json
new file mode 100644
index 00000000000..0bbf25ed926
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9454.json
@@ -0,0 +1 @@
+{"AZATHIOPRINE": 18.846964356701896, "BASILIXIMAB": 373.9499872182839, "BORTEZOMIB": 72.14547868530732, "CELLCEPT": 204.5677559711944, "CICLOSPORIN": 24.471391429892687, "CIDOFOVIR": 175.93598661295954, "MYCOPHENOLATE": 175.33610809555947, "TACROLIMUS": 70.68430142199296, "null": 0.1024299032612309}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9455.json
new file mode 100644
index 00000000000..e3dc63d3494
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9455.json
@@ -0,0 +1 @@
+{"AIMOVIG": 2.1865114401786045, "AMIKACIN": 8.723592742098521, "ARAVA": 0.3456021056993189, "BUDESONIDE": 4.777107204901459, "BYETTA": 2.813994962645586, "CLOPIDOGREL": 1.5641481655700038, "COMIRNATY": 0.0731713027733066, "COSENTYX": 1.5285002396216014, "CYMBALTA": 0.5427281108500343, "ELIQUIS": 5.671230970591765, "ENTYVIO": 2.6319860867702136, "FORSTEO": 1.4934942732004008, "HUMALOG": 1.3053902601119187, "HUMIRA": 3.831192524620031, "JANUVIA": 3.0067486120070237, "MEPOLIZUMAB": 22.02660908161094, "NUCALA": 3.761794322397233, "PEGASYS": 1.4643497404472698, "PLAVIX": 2.246117275205192, "SIMPONI": 1.151319609965713, "SOMAVERT": 126.81002671235574, "SPIKEVAX": 0.0548215597223762, "STELARA": 1.249167319407854, "SUTENT": 0.5671855213410326, "TOZINAMERAN": 0.2423256410070449, "XELJANZ": 3.879219777443032, "XOLAIR": 2.047137667216888, "null": 2.1016441439072464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9456.json
new file mode 100644
index 00000000000..8845a24bd4c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9456.json
@@ -0,0 +1 @@
+{"COMBIVIR": 139.53448020130247, "ELIQUIS": 13.85859090451669, "null": 1.0274320514860724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9457.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9457.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9458.json
new file mode 100644
index 00000000000..2c84681fdbf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9458.json
@@ -0,0 +1 @@
+{"EYLEA": 1001.190882381094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9459.json
new file mode 100644
index 00000000000..52b04e93431
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9459.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.4411944696098051, "VAXZEVRIA": 0.2860899150488348, "null": 0.6054131355758636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/946.json
index 053654cd1b0..dd161db73cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/946.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/946.json
@@ -1 +1 @@
-{"CICLOSPORIN": 40.06317628271132}
\ No newline at end of file
+{"null": 1.5608023183884372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9460.json
new file mode 100644
index 00000000000..21a61f68b0a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9460.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.6367023761225868, "ABILIFY": 3.543843943012655, "AFINITOR": 0.7231084560215608, "APIDRA": 1.4129701168305953, "APIXABAN": 0.51506771644241, "ARIPIPRAZOLE": 0.908412211584654, "CHAMPIX": 2.662425226860789, "CICLOSPORIN": 0.3018221024264343, "COMIRNATY": 0.1992219643313846, "CYMBALTA": 0.4626325264843149, "CYTARABINE": 0.8250287490466512, "DEXAMETHASONE": 0.5777239775672188, "DULOXETINE": 3.706979538426262, "ELIQUIS": 0.3676660768304711, "EMPAGLIFLOZIN": 21.63219746544057, "ENTRESTO": 5.092098920893879, "EXFORGE": 1.754956565894496, "EXJADE": 1.3304269908083994, "FORSTEO": 2.596850090387034, "FORXIGA": 31.40220305198992, "GARDASIL": 0.3924370351288476, "HIZENTRA": 1.645952955019224, "HUMALOG": 0.561950779441069, "IBUPROFEN": 1.8305437197287404, "INSULIN": 2.832422826026742, "JANUMET": 1.147474197522061, "JANUVIA": 1.0315123913094018, "JARDIANCE": 21.094074618381025, "KEPPRA": 0.4121960471800602, "KEYTRUDA": 0.3063354268506491, "LANTUS": 1.734720540689363, "LEVETIRACETAM": 1.117688537795014, "OLANZAPINE": 2.237373156186833, "OPSUMIT": 1.0905047712081166, "PEGASYS": 0.6900742626608402, "PEGINTRON": 0.8117409330492383, "RIBAVIRIN": 2.3949521372821843, "SOLIRIS": 0.8554231961360452, "SPIKEVAX": 0.2991982000583641, "SPINRAZA": 2.795973211520785, "TOZINAMERAN": 0.19219513286922, "TRUVADA": 0.1422577856359663, "VAXZEVRIA": 0.2850797003391204, "VIREAD": 3.669147609982113, "ZYPREXA": 6.273739608579961, "null": 1.757919874502572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9461.json
new file mode 100644
index 00000000000..8aa7d2eddf5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9461.json
@@ -0,0 +1 @@
+{"AIMOVIG": 17.991051349919974, "ATRIPLA": 9.919932317887788, "null": 0.5052144834708597}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9462.json
new file mode 100644
index 00000000000..2a393bf7a8d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9462.json
@@ -0,0 +1 @@
+{"ABILIFY": 5.570862388032117, "BUPRENORPHINE": 20.10350829977817, "BUVIDAL": 160.53676347776343, "COMIRNATY": 0.2152561548424589, "DEXMEDETOMIDINE": 80.6401665042981, "KEPPRA": 2.5639698857344504, "MIDAZOLAM": 17.712209285861192, "ROTATEQ": 18.78964523807031, "SPIKEVAX": 0.0859619864512847, "SUBOXONE": 26.639278099879466, "SYNAGIS": 34.438343270752696, "TOZINAMERAN": 0.2669560582483328, "VAXZEVRIA": 0.1436796409720497, "ZYPREXA": 2.818547464676096, "null": 2.349941650373708}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9463.json
new file mode 100644
index 00000000000..229e94f89ce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9463.json
@@ -0,0 +1 @@
+{"COMIRNATY": 5.414474962457958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9464.json
new file mode 100644
index 00000000000..956b629e7d6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9464.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1021731746559322, "HUMALOG": 5.701978874365637, "HUMIRA": 2.224481445304534, "IBRANCE": 0.9106722981129578, "LANTUS": 3.076475009273464, "PLAVIX": 2.3376860940110795, "SPIKEVAX": 0.658004413199156, "TOZINAMERAN": 0.7707400882204323, "VAXZEVRIA": 0.8314523610100238, "XTANDI": 1.7995806158307412, "ZYPREXA": 2.746893796203969, "null": 0.9967746842256976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9465.json
new file mode 100644
index 00000000000..9165403ebca
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9465.json
@@ -0,0 +1 @@
+{"null": 2.331485051486436}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9466.json
new file mode 100644
index 00000000000..acee0d13b7b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9466.json
@@ -0,0 +1 @@
+{"null": 34.5645924076814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9467.json
new file mode 100644
index 00000000000..2a57cb08b49
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9467.json
@@ -0,0 +1 @@
+{"APIDRA": 4.810536336626019, "CHAMPIX": 0.8693698464558686, "COMIRNATY": 0.5686652474873785, "FENTANYL": 3.315010761135038, "HUMALOG": 3.0792652341296667, "IBRANCE": 3.110999698442249, "LANTUS": 1.062676699899647, "MMRVAXPRO": 1.449070940704217, "MOVYMIA": 46.00860432469364, "NEVANAC": 88.73316532445071, "PEGASYS": 0.6033451700184185, "ROACTEMRA": 2.2350768856200007, "SIMPONI": 6.061300373597041, "SPIKEVAX": 0.0624293410493847, "STELARA": 3.7610729580942976, "TOZINAMERAN": 0.9471638360398582, "null": 3.2161537144727728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9468.json
new file mode 100644
index 00000000000..0b1e05d02aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9468.json
@@ -0,0 +1 @@
+{"AFINITOR": 0.3689136033024082, "AIMOVIG": 6.222900885977203, "ALEMTUZUMAB": 1.2874411024213932, "ANAKINRA": 8.022344704104412, "ARAVA": 0.1509336960082758, "ARIPIPRAZOLE": 1.3334448790255429, "ATRIPLA": 0.140218218989615, "AUBAGIO": 0.3566395935030281, "AVAMYS": 0.7113034910067456, "BELIMUMAB": 17.64763999737211, "BENLYSTA": 1.0596051796186978, "BIKTARVY": 1.510134848570921, "BORTEZOMIB": 5.6455309832841865, "BRINTELLIX": 3.248654445862769, "BYETTA": 0.8942274261679776, "CAPSAICIN": 81.46797197332828, "CHAMPIX": 4.330357210879198, "CICLOSPORIN": 0.6178947230342483, "CIMZIA": 0.2721784973506246, "CIRCADIN": 10.39316768658454, "CLOPIDOGREL": 0.7741331520573448, "COMIRNATY": 0.7337182506495472, "COSENTYX": 1.0608398040780531, "CYMBALTA": 1.50116283969075, "DEXAMETHASONE": 1.1894469217234318, "ELIQUIS": 0.32393591739135, "ENBREL": 1.378623511688008, "ENTRESTO": 0.8268704992981388, "ERENUMAB": 7.247337913942489, "EXFORGE": 1.0895162095616298, "FAMPYRA": 15.779116828344048, "FASLODEX": 0.5596224924937966, "FORSTEO": 0.294015779904715, "FULVESTRANT": 1.3100280360689809, "GALAFOLD": 11.020034157197278, "GARDASIL": 1.0674003407206138, "HUMALOG": 0.6206456347550885, "HUMIRA": 0.5355286678791145, "IBRANCE": 1.2810069188757187, "IBUPROFEN": 0.6873104609379039, "INCIVO": 1.0382154830431232, "JANUVIA": 0.5871007941238879, "JARDIANCE": 0.4563262502114333, "KAFTRIO": 3.435311893355401, "KEPPRA": 0.9403582460654312, "KEYTRUDA": 0.3604991670823207, "LANTUS": 0.3139258396671188, "LATUDA": 2.4843087966396897, "LEVETIRACETAM": 0.9303809951617712, "LEVOFLOXACIN": 0.4566871082624247, "LYRICA": 0.9817010882029058, "MELATONIN": 8.040220079294649, "METHOTREXATE": 0.4201829502283997, "MMRVAXPRO": 2.941150128798684, "NEXAVAR": 0.4388262240714874, "NOT": 1.4397379542812463, "NUCALA": 1.0384220129667106, "OCRELIZUMAB": 3.051282766372598, "OLANZAPINE": 0.796744351066828, "OMALIZUMAB": 0.9321632011437389, "OPSUMIT": 0.4502579057423892, "PANTOPRAZOLE": 1.1233400961606237, "PEGASYS": 0.9177136511818254, "PEGINTRON": 1.8364010337434844, "RITUXIMAB": 0.6317593161115878, "ROTATEQ": 2.753218166522784, "SAXENDA": 0.700989056342905, "SHINGRIX": 1.6726545861425788, "SIMPONI": 0.2536754979132887, "SPIKEVAX": 1.0028107190996096, "STELARA": 0.2833982409846172, "SUBOXONE": 0.3773952057351293, "SUTENT": 0.501808201333825, "TOZINAMERAN": 1.3342075539477307, "TRELEGY": 0.9242909319617368, "VAXZEVRIA": 1.260907562257277, "VFEND": 1.7736359646160036, "VORICONAZOLE": 1.5025723654819796, "VORTIOXETINE": 17.93609851102529, "XELJANZ": 1.347476361248912, "XOLAIR": 0.5846061027510656, "XTANDI": 0.5503126001983087, "XYREM": 3.1288373834274723, "ZOSTAVAX": 2.739354315590271, "ZYPREXA": 0.456386206952644, "null": 0.9404342523320038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9469.json
new file mode 100644
index 00000000000..398dfa8f0d7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9469.json
@@ -0,0 +1 @@
+{"OVITRELLE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/947.json
index f4dc93e70e0..2d25fea8fb9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/947.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/947.json
@@ -1 +1 @@
-{"TOVIAZ": 96.28437012166049, "null": 1.2082337607877938}
\ No newline at end of file
+{"null": 2.212712716221833}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9470.json
new file mode 100644
index 00000000000..3247f0a7469
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9470.json
@@ -0,0 +1 @@
+{"KEPPRA": 10.846030438746771, "SUBOXONE": 12.63788076750332, "null": 3.6517204554079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9471.json
new file mode 100644
index 00000000000..51f59befed8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9471.json
@@ -0,0 +1 @@
+{"ACLASTA": 191.3726483021597, "ARAVA": 0.8086095684632955, "CINRYZE": 172.09378108364504, "ENTYVIO": 35.3439712730702, "HUMIRA": 9.384039242687614, "INFLIXIMAB": 31.750527756816943, "METHOTREXATE": 6.127151393756671, "NAGLAZYME": 155.0225596220758, "RITUXIMAB": 15.920546704437507, "RUCONEST": 92.5799569758312, "SOLIRIS": 47.51892150649618, "null": 0.476907405009097}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9472.json
new file mode 100644
index 00000000000..35fdc18e096
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9472.json
@@ -0,0 +1 @@
+{"SUBOXONE": 76.54748509727662, "null": 1.423092744364314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9473.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9473.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9474.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9474.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9475.json
new file mode 100644
index 00000000000..9df3bb1c25e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9475.json
@@ -0,0 +1 @@
+{"NILOTINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9476.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9476.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9477.json
new file mode 100644
index 00000000000..82da9c827b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9477.json
@@ -0,0 +1 @@
+{"null": 2.037957290839981}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9478.json
new file mode 100644
index 00000000000..31e7726c182
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9478.json
@@ -0,0 +1 @@
+{"null": 5.065319750978021}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9479.json
new file mode 100644
index 00000000000..4d4964641dd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9479.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 27.441982141818876, "null": 1.014706308781459}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/948.json
index 1aa05ca676a..b0aa120fd91 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/948.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/948.json
@@ -1 +1 @@
-{"ARAVA": 2.812469797532208, "ELIQUIS": 3.725319392458172, "null": 1.3185045958494934}
\ No newline at end of file
+{"null": 6.9612375307324665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9480.json
new file mode 100644
index 00000000000..78a2eb1dd1d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9480.json
@@ -0,0 +1 @@
+{"null": 2.0588771490849505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9481.json
new file mode 100644
index 00000000000..41804cb20df
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9481.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 5.591546909025744, "DEXMEDETOMIDINE": 273.6694587616796, "null": 1.9694476907250404}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9482.json
new file mode 100644
index 00000000000..ae8f3a72428
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9482.json
@@ -0,0 +1 @@
+{"PEGASYS": 16.16536088612806, "PEGINTERFERON": 41.67349272695679, "RIBAVIRIN": 28.203000947941906, "null": 0.5144414352940468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9483.json
new file mode 100644
index 00000000000..84bbb05ac4b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9483.json
@@ -0,0 +1 @@
+{"TELMISARTAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9484.json
new file mode 100644
index 00000000000..38b3c0dcf26
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9484.json
@@ -0,0 +1 @@
+{"null": 1.2317673923465602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9485.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9485.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9486.json
new file mode 100644
index 00000000000..b56e02d4920
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9486.json
@@ -0,0 +1 @@
+{"ADCIRCA": 493.2699308308524, "null": 0.6534899698737198}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9487.json
new file mode 100644
index 00000000000..a339bee97f2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9487.json
@@ -0,0 +1 @@
+{"ABACAVIR": 4.956103283268751, "AVASTIN": 11.56752803062478, "AZATHIOPRINE": 4.7058962039892895, "BEVACIZUMAB": 16.883887885960405, "BYETTA": 3.736345191910292, "CAPECITABINE": 7.189873857819523, "EFAVIRENZ": 17.512074404453557, "EMTRICITABINE": 19.21823019636772, "EMTRIVA": 54.101806259511264, "EPIVIR": 18.97363116246328, "IRINOTECAN": 9.865010972032332, "JAKAVI": 5.501747821002779, "KAFTRIO": 10.464843654022705, "KALETRA": 4.433199295069733, "LAMIVUDINE": 19.0316419296194, "NEXAVAR": 2.409117571334489, "NPLATE": 6.3400550753037965, "OCALIVA": 23.18355387462372, "OPSUMIT": 4.102065093365541, "PEGASYS": 5.313027487976421, "PEGINTRON": 1.6392574317879016, "RIBAVIRIN": 8.161965845362309, "SOLIRIS": 4.1963517272845, "STIVARGA": 3.245864818011414, "null": 0.826614979108162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9488.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9488.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9489.json
new file mode 100644
index 00000000000..a02c792dd6c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9489.json
@@ -0,0 +1 @@
+{"ADCIRCA": 190.1001047735297, "OPSUMIT": 15.662210019454564, "null": 0.4582257078611401}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/949.json
index 4b13d424a9c..31d7f92144c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/949.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/949.json
@@ -1 +1 @@
-{"BETMIGA": 40.77052339943651, "FORSTEO": 2.032389211148656, "GARDASIL": 1.5362598636124056, "JARDIANCE": 6.405618116516284, "OMALIZUMAB": 18.334293330578927, "TOVIAZ": 39.66649432765731, "TOZINAMERAN": 1.1313621594153822, "null": 1.0564745795938757}
\ No newline at end of file
+{"ALDARA": 34.2725169819962, "AMELUZ": 78.91465391185146, "BUPRENORPHINE": 8.072370564766905, "COMIRNATY": 0.2171184754645123, "EVRA": 76.49688124651175, "KENTERA": 266.6039195958152, "OPSUMIT": 0.7565035856708947, "QUTENZA": 79.07628640548619, "SPIKEVAX": 0.4873353772942379, "VAXZEVRIA": 0.2114001058022644, "null": 8.85154145913907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9490.json
new file mode 100644
index 00000000000..ffed2e44063
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9490.json
@@ -0,0 +1 @@
+{"null": 0.8953782293383834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9491.json
new file mode 100644
index 00000000000..640898ffde2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9491.json
@@ -0,0 +1 @@
+{"ADCIRCA": 435.214280130478, "null": 1.3183930208231711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9492.json
new file mode 100644
index 00000000000..ab84ba4a0b5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9492.json
@@ -0,0 +1 @@
+{"IRINOTECAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9493.json
new file mode 100644
index 00000000000..b321a609bdf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9493.json
@@ -0,0 +1 @@
+{"null": 0.5036571925135453}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9494.json
new file mode 100644
index 00000000000..cd6a488d6b4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9494.json
@@ -0,0 +1 @@
+{"null": 1.0160645214141928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9495.json
new file mode 100644
index 00000000000..76040ff9f95
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9495.json
@@ -0,0 +1 @@
+{"APIXABAN": 1.43048507276748, "AVASTIN": 7.56095306879073, "BEVACIZUMAB": 8.670738588656027, "CABOMETYX": 4.837695702680964, "CICLOSPORIN": 0.9495351173425765, "COMIRNATY": 0.6295738250040042, "ELIQUIS": 0.9535866063489884, "ESOMEPRAZOLE": 6.1983741091391495, "EXVIERA": 18.7773343372558, "HARVONI": 9.431582628508904, "INCIVO": 3.664772253673176, "JAKAVI": 7.404538962492322, "JANUMET": 1.8943729353723444, "JANUVIA": 2.159127344941448, "LENVIMA": 16.95733373696746, "NEXAVAR": 10.14030283768059, "NOVOSEVEN": 34.18865079316216, "NPLATE": 9.267955716133097, "OLYSIO": 16.432735008781343, "PEGASYS": 1.2763448634717611, "PEGINTRON": 2.114847633981307, "RIBAVIRIN": 11.541880933481238, "RINVOQ": 4.479269291615943, "SOLIRIS": 5.933926847168577, "SOVALDI": 15.421635932283817, "SPIKEVAX": 0.4715202966071923, "SUTENT": 0.749305637830153, "TESTOSTERONE": 22.914358530816408, "TOZINAMERAN": 0.4685100426928035, "VAXZEVRIA": 2.190671791872164, "XELJANZ": 0.7188251224210094, "null": 0.3614349794975283}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9496.json
new file mode 100644
index 00000000000..8f53f8b4864
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9496.json
@@ -0,0 +1 @@
+{"DOCETAXEL": 56.970378319483046, "null": 1.7464197237650951}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9497.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9497.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9498.json
new file mode 100644
index 00000000000..b95003c5a19
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9498.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.7832494036167017, "VAXZEVRIA": 4.698057238930264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9499.json
new file mode 100644
index 00000000000..b8a3770060f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9499.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 4.209914209644631, "null": 0.9714101814927028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/95.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/95.json
index dad0224d86f..f47193e7f83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/95.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/95.json
@@ -1 +1 @@
-{"TOZINAMERAN": 2.484405858147312}
\ No newline at end of file
+{"ARIPIPRAZOLE": 40.25045883080527, "COMIRNATY": 0.2260571941211274, "STELARA": 5.648569464979159, "VAXZEVRIA": 0.2082297784176362, "null": 0.7528790927469782}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/950.json
index b8b6bafa867..61f42fb533b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/950.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/950.json
@@ -1 +1 @@
-{"null": 2.1222868188317268}
\ No newline at end of file
+{"AMELUZ": 1764.2703490542085, "COMIRNATY": 0.1861936258859224, "null": 4.25800318374373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9500.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9500.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9501.json
new file mode 100644
index 00000000000..034917e5ad2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9501.json
@@ -0,0 +1 @@
+{"null": 0.40485381406118}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9502.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9502.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9503.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9503.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9504.json
new file mode 100644
index 00000000000..00a88f53c79
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9504.json
@@ -0,0 +1 @@
+{"null": 17.469312377333626}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9505.json
new file mode 100644
index 00000000000..6221529bc1a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9505.json
@@ -0,0 +1 @@
+{"null": 1.2741546040657432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9506.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9506.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9507.json
new file mode 100644
index 00000000000..5b5a98deb97
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9507.json
@@ -0,0 +1 @@
+{"CAPECITABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9508.json
new file mode 100644
index 00000000000..cc46ea10ac6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9508.json
@@ -0,0 +1 @@
+{"null": 1.3206517134204443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9509.json
new file mode 100644
index 00000000000..ed527b3a504
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9509.json
@@ -0,0 +1 @@
+{"null": 4.035741465701978}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/951.json
index 5effedeb2d6..f504ba29dd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/951.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/951.json
@@ -1 +1 @@
-{"OXYBUTYNIN": 102.10703220327738, "PEGINTRON": 5.88492601916547, "TOVIAZ": 46.27468605207611, "null": 1.5776483300522015}
\ No newline at end of file
+{"BUPRENORPHINE": 16.76502574228821, "COMIRNATY": 0.0301472988454822, "EVRA": 74.67275309781097, "KENTERA": 130.10739102167346, "SPIKEVAX": 0.1421787460165129, "null": 13.540943445716744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9510.json
new file mode 100644
index 00000000000..7ccfad8aebb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9510.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 0.4995496066332744, "COMIRNATY": 0.6338552842921823, "CYMBALTA": 0.4917176529784315, "JAKAVI": 2.260410612159087, "LYRICA": 6.389100903772428, "NOT": 9.798881532023334, "RINVOQ": 3.4027934212015105, "SHINGRIX": 44.700391768942254, "SPIKEVAX": 0.3600741324132026, "TOZINAMERAN": 0.3461402602767409, "VAXZEVRIA": 0.1225110746857818, "XELJANZ": 1.1576810591776172, "ZOSTAVAX": 329.0078577054292, "null": 0.1968851683144129}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9511.json
new file mode 100644
index 00000000000..6089179d965
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9511.json
@@ -0,0 +1 @@
+{"OPTIMARK": 43.121424622012185, "ZOSTAVAX": 14.020104254485888, "null": 0.6921908276883452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9512.json
new file mode 100644
index 00000000000..1272c0ba257
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9512.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.0505550427171858, "FENTANYL": 6.154451538598208, "GARDASIL": 1.9854357365500932, "SPINRAZA": 6081.1811400013785, "null": 0.1431839771849116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9513.json
new file mode 100644
index 00000000000..b7513734a91
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9513.json
@@ -0,0 +1 @@
+{"AZILECT": 1595.9617023553117, "TOVIAZ": 133.10271977977422, "null": 1.8581982561790984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9514.json
new file mode 100644
index 00000000000..a7e90bb110e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9514.json
@@ -0,0 +1 @@
+{"null": 0.6588557304492099}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9515.json
new file mode 100644
index 00000000000..d7604a3d709
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9515.json
@@ -0,0 +1 @@
+{"null": 1.319206425250996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9516.json
new file mode 100644
index 00000000000..eb72893b9ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9516.json
@@ -0,0 +1 @@
+{"ARAVA": 0.2158000975748492, "AUBAGIO": 1.251799130772728, "CIMZIA": 1.8162135468671208, "CYMBALTA": 0.8875843038824369, "ELIQUIS": 1.9744121186581065, "ENBREL": 3.4375570425540234, "EXJADE": 2.508990298476559, "FENTANYL": 9.004853631169757, "FORSTEO": 2.792260712174081, "HUMALOG": 4.741299789569399, "HUMAN": 5.860460458846941, "HUMIRA": 2.290166650847856, "IBRANCE": 0.7699600733661411, "INSULIN": 2.3069467458300186, "JANUMET": 1.4868653825698832, "JANUVIA": 2.063094705788182, "JARDIANCE": 4.687792406293442, "KEYTRUDA": 0.6680527810444968, "LANTUS": 1.63261982858763, "NPLATE": 3.8925661779645377, "NUCALA": 1.2170649112185996, "OFEV": 2.691475955140743, "OMALIZUMAB": 3.2785576624075623, "OPSUMIT": 1.4274534698085848, "RINVOQ": 2.8859516441939697, "SIMPONI": 2.144096932131036, "SPINRAZA": 57.565698813811885, "STELARA": 1.6023958027379803, "SUTENT": 1.3661194068358342, "TRACLEER": 4.00504605451263, "TRELEGY": 2.3833721641399723, "TREMFYA": 4.920595730716917, "VAXZEVRIA": 0.1015626199605093, "XELJANZ": 4.042585796837883, "XOLAIR": 1.030742597973045, "ZYPADHERA": 88.53570773576514, "null": 1.05120545739605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9517.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9517.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9518.json
new file mode 100644
index 00000000000..589d3b173c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9518.json
@@ -0,0 +1 @@
+{"ANAKINRA": 147.89535485496316}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9519.json
new file mode 100644
index 00000000000..ce23a3ac208
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9519.json
@@ -0,0 +1 @@
+{"null": 0.6576612364450601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/952.json
index e65103a936e..f9ae641d5ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/952.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/952.json
@@ -1 +1 @@
-{"null": 1.1425222380734628}
\ No newline at end of file
+{"ALDARA": 90.73690072666808, "AMELUZ": 97.91933944061462, "COMIRNATY": 1.0425975809145405, "EVRA": 38.631953824218456, "KENTERA": 68.09048612112686, "QUTENZA": 16.39090043961273, "SPIKEVAX": 2.3882138687445185, "VAXZEVRIA": 3.855009832658676, "ZYCLARA": 39.556561252101694, "null": 1.1199194917915112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9520.json
new file mode 100644
index 00000000000..37113eaa320
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9520.json
@@ -0,0 +1 @@
+{"null": 0.6449150114738356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9521.json
new file mode 100644
index 00000000000..96b3835d685
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9521.json
@@ -0,0 +1 @@
+{"null": 0.9994281994518696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9522.json
new file mode 100644
index 00000000000..a1a79557626
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9522.json
@@ -0,0 +1 @@
+{"SPINRAZA": 204.8236967187005, "null": 0.5063454530123213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9523.json
new file mode 100644
index 00000000000..5332f05fb0c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9523.json
@@ -0,0 +1 @@
+{"null": 0.584003753717194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9524.json
new file mode 100644
index 00000000000..6132101fc2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9524.json
@@ -0,0 +1 @@
+{"BRILIQUE": 12.535692895271476, "CLOPIDOGREL": 9.261509207725378, "ELIQUIS": 14.601449646913736, "PLAVIX": 15.37349921412588, "SPINRAZA": 19.88214714778649, "null": 1.5310066149932386}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9525.json
new file mode 100644
index 00000000000..8a99e193dbb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9525.json
@@ -0,0 +1 @@
+{"ELIQUIS": 32.96856311118378, "null": 0.6983382272081777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9526.json
new file mode 100644
index 00000000000..cf9692b4222
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9526.json
@@ -0,0 +1 @@
+{"ANGIOX": 34.2588339284578, "ARAVA": 0.1375794428878939, "BRIDION": 8.739605800234902, "BRILIQUE": 11.313045991047142, "CABOMETYX": 1.9094789031577457, "CELLCEPT": 1.0237275434907018, "CLOPIDOGREL": 13.035514719904429, "COMIRNATY": 0.0125327870104068, "CYMBALTA": 0.4575713061642802, "ELIQUIS": 23.994847494785, "ENOXAPARIN": 9.70087128249471, "FENTANYL": 1.2875601309063376, "FIRDAPSE": 4.867379872549266, "HEMLIBRA": 26.97633434903145, "JAKAVI": 4.507086874985171, "KEPPRA": 0.4523062088517903, "LEVEMIR": 2.065882073576722, "LIXIANA": 11.79132078421702, "MACITENTAN": 25.2356376259538, "MIDAZOLAM": 2.403334014390584, "NOVOSEVEN": 18.917217920078333, "OCTREOTIDE": 40.42174416181631, "OPSUMIT": 0.9011616651445372, "PLAVIX": 22.00160880947496, "SOLIRIS": 4.402485750542063, "SPINRAZA": 7.181089276620807, "STELARA": 0.7726871790712442, "SUTENT": 0.4149980110231571, "TICAGRELOR": 5.864217060738054, "XARELTO": 15.694598329229065, "null": 1.551804688887668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9527.json
new file mode 100644
index 00000000000..444888b71da
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9527.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": 36.39576517963808, "null": 0.7520533219407085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9528.json
new file mode 100644
index 00000000000..6100003a7c2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9528.json
@@ -0,0 +1 @@
+{"BYETTA": 241.0856269030708, "EFAVIRENZ": 232.15547212950776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9529.json
new file mode 100644
index 00000000000..4c3b4dcdbf3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9529.json
@@ -0,0 +1 @@
+{"ARAVA": 0.2764814517851144, "BEXTRA": 129.32191508716056, "BYETTA": 3.6446276271560185, "CICLOSPORIN": 1.1839996787748794, "CIMZIA": 2.9942962386763763, "COSENTYX": 3.4557688495652785, "ELIQUIS": 2.488561684577946, "ENBREL": 4.203931639178593, "FORSTEO": 2.870297609602072, "HUMALOG": 3.640074564430168, "HUMIRA": 8.478065710577587, "HYDROCORTISONE": 7.488752269004917, "IBRANCE": 1.2384885455364831, "JARDIANCE": 2.499970506852168, "LANTUS": 1.0941556979593134, "RINVOQ": 5.760553634569338, "SIMPONI": 12.19361889626844, "SPINRAZA": 23.51661666310653, "SUTENT": 0.7346108976238538, "XELJANZ": 9.683612925116764, "null": 1.003869964476137}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/953.json
index 1c2697a08da..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/953.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/953.json
@@ -1 +1 @@
-{"ELIQUIS": 13.003589631100738, "KEYTRUDA": 9.258182270334702}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9530.json
new file mode 100644
index 00000000000..617fbe257e3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9530.json
@@ -0,0 +1 @@
+{"null": 0.8321346898984554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9531.json
new file mode 100644
index 00000000000..f8ab5d7ddae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9531.json
@@ -0,0 +1 @@
+{"null": 0.3891738137008944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9532.json
new file mode 100644
index 00000000000..9983b88211b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9532.json
@@ -0,0 +1 @@
+{"null": 0.9020899132525624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9533.json
new file mode 100644
index 00000000000..da0a2610330
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9533.json
@@ -0,0 +1 @@
+{"null": 0.5775595871391983}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9534.json
new file mode 100644
index 00000000000..8908d041f86
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9534.json
@@ -0,0 +1 @@
+{"null": 0.7199158905365257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9535.json
new file mode 100644
index 00000000000..dd14a78fe44
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9535.json
@@ -0,0 +1 @@
+{"SPINRAZA": 107.72222377474203, "null": 0.6184948816365008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9536.json
new file mode 100644
index 00000000000..64582c590ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9536.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.2923023094204713, "null": 0.6774515293431573}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9537.json
new file mode 100644
index 00000000000..95a2e305142
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9537.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 83.89915286852765, "AZATHIOPRINE": 18.13618999637453, "BASILIXIMAB": 55.8031209991636, "BUSILVEX": 71.99214415824973, "BUSULFAN": 51.59080792676637, "CAELYX": 20.86388934609301, "CARMUSTINE": 32.85664997954095, "CELLCEPT": 74.08818644654824, "CICLOSPORIN": 114.55769314265794, "CYTARABINE": 3.5347068757922746, "DINUTUXIMAB": 95.8295562186226, "GANCICLOVIR": 27.977122528355924, "METHOTREXATE": 4.8671434813260905, "MYCOPHENOLATE": 67.84965207266681, "RAPAMUNE": 9.415797922665076, "RITUXIMAB": 6.613662652376533, "TACROLIMUS": 23.09285420269395, "null": 0.27851211354362}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9538.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9538.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9539.json
new file mode 100644
index 00000000000..f054df30966
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9539.json
@@ -0,0 +1 @@
+{"COMIRNATY": 13.14648040669851, "GARDASIL": 3.322719634718234, "SPIKEVAX": 2.5718315906901013, "VAXZEVRIA": 0.6986568700776249, "null": 0.0472997889250566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/954.json
index 564a07c1805..ee11603e30d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/954.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/954.json
@@ -1 +1 @@
-{"CICLOSPORIN": 15.400606430105444, "HUMIRA": 17.096688236784093, "PANTOPRAZOLE": 44.18745718390277, "STELARA": 11.079576587519878}
\ No newline at end of file
+{"ALDARA": 634.0270679650852, "AMELUZ": 4146.579006978819, "IMIQUIMOD": 494.9731889743321, "ZYCLARA": 458.819205636191, "null": 2.840141202193644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9540.json
new file mode 100644
index 00000000000..7abb4b1382b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9540.json
@@ -0,0 +1 @@
+{"COMIRNATY": 8.03256636587388, "SPIKEVAX": 2.269776931213781, "TOZINAMERAN": 1.8176169225046244, "VAXZEVRIA": 0.8061574464715232, "null": 0.08791309477733}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9541.json
new file mode 100644
index 00000000000..c6490dabd28
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9541.json
@@ -0,0 +1 @@
+{"null": 1.9291724658549845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9542.json
new file mode 100644
index 00000000000..f90685d4840
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9542.json
@@ -0,0 +1 @@
+{"KYMRIAH": 14899.032451876572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9543.json
new file mode 100644
index 00000000000..62b7303de26
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9543.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 20.930327179253307, "ZYPADHERA": 3968.163149506781, "null": 0.69823177315298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9544.json
new file mode 100644
index 00000000000..ddf3667cf09
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9544.json
@@ -0,0 +1 @@
+{"TESTOSTERONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9545.json
new file mode 100644
index 00000000000..51ce01c9af8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9545.json
@@ -0,0 +1 @@
+{"null": 1.145626223782917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9546.json
new file mode 100644
index 00000000000..00765d39494
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9546.json
@@ -0,0 +1 @@
+{"null": 1.039154314739532}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9547.json
new file mode 100644
index 00000000000..aeb412d86c0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9547.json
@@ -0,0 +1 @@
+{"AIMOVIG": 128.75248976578484, "null": 0.6931750855674853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9548.json
new file mode 100644
index 00000000000..55409bc53a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9548.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 34.443209289595025, "COMIRNATY": 0.3451553045341511, "HUMIRA": 48.42026989994539, "SPIKEVAX": 1.6251186940187752, "null": 0.6987032112944673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9549.json
new file mode 100644
index 00000000000..23161687fd9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9549.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.395722096780584, "AIMOVIG": 2.7215956161450374, "ATRIPLA": 1.1646588145965668, "AVAMYS": 2.9030081891625623, "BENLYSTA": 3.158375253663774, "BUPRENORPHINE": 10.870707617440395, "CHAMPIX": 1.5219112085969908, "CIMZIA": 0.6899539656754391, "COMIRNATY": 0.1555140982511484, "CYMBALTA": 2.884716938286347, "DESCOVY": 40.6177379573548, "FENTANYL": 4.97584077608466, "GARDASIL": 2.764295341272708, "IBRANCE": 0.9059251127083492, "IBUPROFEN": 2.6121524953192066, "LATUDA": 15.111620668454814, "LYRICA": 4.85131486542355, "MEPOLIZUMAB": 6.664277284819295, "OLANZAPINE": 2.308040480933825, "PEGASYS": 0.7518008245076407, "SPIKEVAX": 0.0940684667671166, "STRIBILD": 4.149638767731106, "SUBOXONE": 5.350373633738211, "TOZINAMERAN": 0.6271343448164026, "TRUVADA": 1.7382298802991565, "VAXZEVRIA": 0.1581580484320746, "XELJANZ": 1.1471586235282492, "ZOSTAVAX": 4.142098577639284, "ZYPREXA": 1.6846851543003565, "null": 1.7680943251399757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/955.json
index e9675a40ef3..ee3a7bb5b82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/955.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/955.json
@@ -1 +1 @@
-{"AZACITIDINE": 75.60746659487052, "CICLOSPORIN": 4.113041541759277, "EXJADE": 8.574264750041122, "JAKAVI": 170.59371217443262, "KYMRIAH": 86.52630852031776, "NPLATE": 18.90257243573125}
\ No newline at end of file
+{"null": 13.592799754552772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9550.json
new file mode 100644
index 00000000000..090770be764
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9550.json
@@ -0,0 +1 @@
+{"null": 2.044969251576027}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9551.json
new file mode 100644
index 00000000000..fab4cf22167
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9551.json
@@ -0,0 +1 @@
+{"EYLEA": 67.87368499748167, "ZOSTAVAX": 41.5318919402234, "null": 0.8749629045125117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9552.json
new file mode 100644
index 00000000000..f253af1c7de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9552.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 5.217693507018495, "ASPARAGINASE": 60.56914711338992, "AVASTIN": 8.249766445771781, "AXITINIB": 15.43194316514135, "BASILIXIMAB": 11.779810246461874, "BEVACIZUMAB": 16.016669814117023, "BORTEZOMIB": 17.30020423427628, "BUSULFAN": 19.11175806849752, "CABOMETYX": 4.378937685188248, "CAPECITABINE": 3.10251009297439, "CARFILZOMIB": 5.375223660887612, "CELLCEPT": 7.766150526497181, "CICLOSPORIN": 32.393516819502004, "COMIRNATY": 0.019846840599981, "CYTARABINE": 12.250743157607856, "DARZALEX": 3.54957101093443, "DEXAMETHASONE": 4.9681759942325225, "ENOXAPARIN": 3.1577240770324004, "FENTANYL": 0.5991534178838175, "FOTIVDA": 27.495954427717464, "HUMAN": 18.230141699028863, "ICLUSIG": 5.8027476188123925, "INLYTA": 16.298877596549946, "KEYTRUDA": 2.826767572844566, "KYPROLIS": 13.729202611871049, "LENVIMA": 12.24705296816257, "METHOTREXATE": 6.24438767557578, "MYCOPHENOLATE": 5.638336859025644, "NEXAVAR": 1.8299282512632653, "NOXAFIL": 6.140828521412818, "ONCASPAR": 15.444983639313, "PAZOPANIB": 12.325488290256157, "PEGASYS": 0.2811599070263486, "PEMBROLIZUMAB": 3.855617041895293, "POSACONAZOLE": 14.205863310938328, "RITUXIMAB": 3.469657766791467, "SOLIRIS": 2.649538772708413, "SPIKEVAX": 0.0288113392144719, "STELARA": 3.166322437772485, "STIVARGA": 7.168029557811422, "SUNITINIB": 22.447372708534235, "SUTENT": 2.1504805957322097, "TACROLIMUS": 13.802264725416752, "VAXZEVRIA": 0.0175846695954671, "VFEND": 1.4360096658112311, "VORICONAZOLE": 3.1651550451971406, "VOTRIENT": 10.417503973718985, "XTANDI": 5.153549072430196, "null": 0.7599514561180517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9553.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9553.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9554.json
new file mode 100644
index 00000000000..939b4d28f1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9554.json
@@ -0,0 +1 @@
+{"ATRIPLA": 56.9452965698249}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9555.json
new file mode 100644
index 00000000000..46a93a7b46f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9555.json
@@ -0,0 +1 @@
+{"BRIVARACETAM": 345.63629709145465, "LEVETIRACETAM": 31.91848511431913, "null": 0.7593563279689826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9556.json
new file mode 100644
index 00000000000..f5b215fde73
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9556.json
@@ -0,0 +1 @@
+{"LEVETIRACETAM": 272.89342297561643, "null": 0.3096098963220699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9557.json
new file mode 100644
index 00000000000..0d9fa4a3df0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9557.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1496427892135316, "GARDASIL": 6.998001069471346, "KEPPRA": 20.824477052313743, "MMRVAXPRO": 4.896427972657276, "SPIKEVAX": 0.3798637289156195, "TOZINAMERAN": 0.7717403090080632, "null": 2.3191996431923148}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9558.json
new file mode 100644
index 00000000000..473469b72a7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9558.json
@@ -0,0 +1 @@
+{"null": 0.6127986984377405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9559.json
new file mode 100644
index 00000000000..08433699e2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9559.json
@@ -0,0 +1 @@
+{"AIMOVIG": 0.4035837387408418, "CHAMPIX": 0.7772004586354974, "COMIRNATY": 5.84964710163738, "ELIQUIS": 0.3510361107689961, "EVISTA": 2.674091700461756, "MODERNA": 1.969682548019393, "OCRELIZUMAB": 1.1448066951751694, "SPIKEVAX": 2.5693829418963903, "TOZINAMERAN": 3.342865482825633, "VAXZEVRIA": 0.9807943541948702, "null": 0.4190766489283442}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/956.json
index 68808aaf183..5adea02d97d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/956.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/956.json
@@ -1 +1 @@
-{"DASATINIB": 332.5361763327955, "ICLUSIG": 292.1844386071012, "JAKAVI": 59.608178156650254, "SPRYCEL": 109.22375482219668, "TASIGNA": 65.787395033958}
\ No newline at end of file
+{"ALDARA": 21.15855554628843, "AMELUZ": 252.3272667956982, "COMIRNATY": 2.020440724674948, "NEULASTA": 2.047586347678803, "QUTENZA": 30.260150448059377, "SHINGRIX": 0.9508725346340244, "SPIKEVAX": 3.126222973815848, "VAXZEVRIA": 4.015728555578475, "null": 0.7614498642202285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9560.json
new file mode 100644
index 00000000000..4b852051f16
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9560.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 2.068250237388988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9561.json
new file mode 100644
index 00000000000..003e2d6f376
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9561.json
@@ -0,0 +1 @@
+{"FENTANYL": 1502.4389181727115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9562.json
new file mode 100644
index 00000000000..2e9129552ba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9562.json
@@ -0,0 +1 @@
+{"null": 15.200550388784546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9563.json
new file mode 100644
index 00000000000..0fff568b3ef
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9563.json
@@ -0,0 +1 @@
+{"FENTANYL": 51.34439823983912, "null": 5.957057696695992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9564.json
new file mode 100644
index 00000000000..28121f4aaa0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9564.json
@@ -0,0 +1 @@
+{"null": 4.139418728484751}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9565.json
new file mode 100644
index 00000000000..4f96677e5be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9565.json
@@ -0,0 +1 @@
+{"null": 0.2720350805993502}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9566.json
new file mode 100644
index 00000000000..5d2c62c7cc9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9566.json
@@ -0,0 +1 @@
+{"null": 1.4693700300919337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9567.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9567.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9568.json
new file mode 100644
index 00000000000..dcdcf3b20b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9568.json
@@ -0,0 +1 @@
+{"DEXDOR": 14791.92902198019, "FENTANYL": 17.042829888846647, "MIDAZOLAM": 40.881192247353525, "SUFENTANIL": 809.6657414852194, "null": 0.1124993841234699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9569.json
new file mode 100644
index 00000000000..3748ed9c418
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9569.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 28.41094056965226, "null": 1.4243587815830083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/957.json
index 7b231324e0b..af25fae32aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/957.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/957.json
@@ -1 +1 @@
-{"SPRYCEL": 220.94495881242807}
\ No newline at end of file
+{"ALDARA": 1589.5166149094773, "null": 2.372113449575008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9570.json
new file mode 100644
index 00000000000..c1bbb4b698c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9570.json
@@ -0,0 +1 @@
+{"CELLCEPT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9571.json
new file mode 100644
index 00000000000..feedf661a28
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9571.json
@@ -0,0 +1 @@
+{"null": 0.6336028731888266}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9572.json
new file mode 100644
index 00000000000..dd161db73cc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9572.json
@@ -0,0 +1 @@
+{"null": 1.5608023183884372}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9573.json
new file mode 100644
index 00000000000..a972e5b2bc6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9573.json
@@ -0,0 +1 @@
+{"ELIQUIS": 14.256454761358343, "null": 1.1884035515330909}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9574.json
new file mode 100644
index 00000000000..7a8dae4cdd9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9574.json
@@ -0,0 +1 @@
+{"null": 1.109709617475721}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9575.json
new file mode 100644
index 00000000000..2387b48886b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9575.json
@@ -0,0 +1 @@
+{"ARAVA": 0.2819629671085361, "BRIVIACT": 15.260027866893164, "BUPIVACAINE": 9.391780331867553, "BYETTA": 3.716992369920854, "CELLCEPT": 3.960664057259996, "CHLORHEXIDINE": 11.793522732298658, "CICLOSPORIN": 1.3680940757350024, "CIMZIA": 1.8989709070753376, "CYMBALTA": 2.927777188698605, "HUMALOG": 3.218317673877612, "HUMIRA": 2.723031372099268, "IBRANCE": 1.880575035708577, "LANTUS": 2.0365265190624977, "METHOTREXATE": 2.71009665931964, "NEXAVAR": 1.966863427245472, "OPSUMIT": 2.066705991246776, "ROACTEMRA": 3.5317002388020224, "SIMPONI": 3.948586793942425, "SOLIRIS": 2.700912882721453, "STELARA": 3.3379872842766893, "SUTENT": 1.9672407147176088, "XELJANZ": 5.952842732383256, "XOLAIR": 2.118523083237267, "null": 0.9880892327516896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9576.json
new file mode 100644
index 00000000000..2a6a9d7ab0e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9576.json
@@ -0,0 +1 @@
+{"BUPIVACAINE": 41.71038607704833, "COMIRNATY": 0.0880984906362586, "FENTANYL": 5.616747487689004, "MISOPROSTOL": 274.6963063577937, "NOVOSEVEN": 49.250872995599, "SUBOXONE": 8.780104020573138, "TOZINAMERAN": 0.5832525133103744, "null": 2.94808827163591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9577.json
new file mode 100644
index 00000000000..616457c7093
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9577.json
@@ -0,0 +1 @@
+{"null": 6.781126114714091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9578.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9578.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9579.json
new file mode 100644
index 00000000000..4f7cb8d6fae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9579.json
@@ -0,0 +1 @@
+{"ELIQUIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/958.json
index adcf8bcb77c..c921554c287 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/958.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/958.json
@@ -1 +1 @@
-{"ASPARAGINASE": 35.1839188335527, "CICLOSPORIN": 7.083545135005069, "CYTARABINE": 29.330349030159496, "JAKAVI": 77.27963742127534}
\ No newline at end of file
+{"MMRVAXPRO": 8.755671041850686, "null": 12.74684293723596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9580.json
new file mode 100644
index 00000000000..c18fd12907c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9580.json
@@ -0,0 +1 @@
+{"APIDRA": 21.526668227119, "HUMALOG": 16.06678509952666, "INSULIN": 55.21317761805444, "NOVORAPID": 97.12008934623589, "null": 0.299360932774559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9581.json
new file mode 100644
index 00000000000..b4ffa2fdaba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9581.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 11.61807519733189, "null": 1.1595023427676845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9582.json
new file mode 100644
index 00000000000..27c420cc88b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9582.json
@@ -0,0 +1 @@
+{"ZYPREXA": 58.74823363078491, "null": 0.64808008921029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9583.json
new file mode 100644
index 00000000000..9e882f3291a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9583.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.6440753295420214, "COMIRNATY": 2.609584792719369, "CYMBALTA": 1.4012847466229483, "EMGALITY": 622.6024985866085, "GARDASIL": 89.93581689493419, "SPIKEVAX": 1.127102335938795, "TOZINAMERAN": 3.883613187281696, "VAXZEVRIA": 0.4546285117403242, "null": 0.1725442951136571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9584.json
new file mode 100644
index 00000000000..bac674c2fa1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9584.json
@@ -0,0 +1 @@
+{"null": 1.2435810430680123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9585.json
new file mode 100644
index 00000000000..02a444b811f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9585.json
@@ -0,0 +1 @@
+{"null": 2.0195093488316496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9586.json
new file mode 100644
index 00000000000..d64e75fed53
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9586.json
@@ -0,0 +1 @@
+{"ABILIFY": 10.401753743678224, "ARIPIPRAZOLE": 4.452125990387526, "ASPARAGINASE": 17.641828859563073, "BEXSERO": 23.66226453249875, "COMIRNATY": 0.1722664087044924, "COMTAN": 27.45842688537308, "EVISTA": 9.125332744012123, "GARDASIL": 8.586208258678164, "KEPPRA": 1.469178635994931, "LEVETIRACETAM": 2.933612361429914, "OLANZAPINE": 13.450314714228336, "SPIKEVAX": 0.4949792174146389, "ZYPREXA": 3.7193035578131823, "null": 1.709233310814382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9587.json
new file mode 100644
index 00000000000..848c2b0dd3e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9587.json
@@ -0,0 +1 @@
+{"null": 2.207018844802872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9588.json
new file mode 100644
index 00000000000..05e1fd6d6cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9588.json
@@ -0,0 +1 @@
+{"ABILIFY": 2.3660904453565577, "BUPRENORPHINE": 2.120164249262097, "CLOPIDOGREL": 4.421861164374184, "CYMBALTA": 3.570415685967619, "DEXMEDETOMIDINE": 34.47845662404311, "ELIQUIS": 1.0164751504543157, "EMTRIVA": 73.46934545318256, "FENTANYL": 6.541799013283196, "GLIBENCLAMIDE": 15.534782092063216, "IBUPROFEN": 2.097540495392128, "KEPPRA": 0.8580574421311067, "LANTUS": 0.8621687816065118, "LEVETIRACETAM": 4.641629947325373, "LYRICA": 5.170140511808287, "MIDAZOLAM": 4.559326478525187, "NOXAFIL": 12.11631913255806, "PLAVIX": 2.329042344302027, "PREGABALIN": 8.949701258362044, "ZYPREXA": 3.118373461953376, "null": 2.744083704368119}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9589.json
new file mode 100644
index 00000000000..0300b260767
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9589.json
@@ -0,0 +1 @@
+{"null": 5.144863402528774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/959.json
index f5f6ffa946f..f609d2c09e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/959.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/959.json
@@ -1 +1 @@
-{"BOSUTINIB": 143.83841396040518, "BUSULFAN": 20.97366734128727, "CYTARABINE": 11.018826704935348, "DASATINIB": 289.2587294832939, "GLIVEC": 151.94204221717925, "ICLUSIG": 230.3105141951547, "IMATINIB": 141.51094928623797, "NILOTINIB": 286.3203678106457, "SPRYCEL": 48.87093153735267, "TASIGNA": 277.4737966803825}
\ No newline at end of file
+{"ALDARA": 56.72354895590348, "AMELUZ": 160.43156103925915, "BUPRENORPHINE": 4.570091944039827, "EVRA": 41.520771892426325, "QUTENZA": 592.120629817139, "null": 7.221497357676755}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9590.json
new file mode 100644
index 00000000000..97d9883ebbe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9590.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 22.05702631432785, "ENTYVIO": 112.7664708450598, "HUMIRA": 39.47719949399934, "STELARA": 23.346697633826054, "null": 0.1897544221825753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9591.json
new file mode 100644
index 00000000000..84ef56e525a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9591.json
@@ -0,0 +1 @@
+{"null": 8.003394656024124}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9592.json
new file mode 100644
index 00000000000..939dd761170
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9592.json
@@ -0,0 +1 @@
+{"null": 2.112743115309849}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9593.json
new file mode 100644
index 00000000000..7c474540fe2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9593.json
@@ -0,0 +1 @@
+{"null": 0.7601342061645192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9594.json
new file mode 100644
index 00000000000..ee640751074
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9594.json
@@ -0,0 +1 @@
+{"null": 1.9001059167326195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9595.json
new file mode 100644
index 00000000000..21dd3446cfc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9595.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.558899743433641, "BUPIVACAINE": 7.208650426649845, "BUPRENORPHINE": 6.525271893335568, "CICLOSPORIN": 5.476864456528416, "CIMZIA": 1.5708002319104062, "COMBIVIR": 7.103361370899588, "COMIRNATY": 0.0646099982042727, "CYMBALTA": 0.8059728487834392, "DEXAMETHASONE": 2.72606963164392, "DULOXETINE": 18.221282538468664, "ENOXAPARIN": 5.849637320878053, "ENTYVIO": 2.261628754270127, "FENTANYL": 3.1776582570240794, "GARDASIL": 3.0442574078627533, "HUMALOG": 4.591032391063967, "INSULIN": 11.984442666216708, "KEPPRA": 4.932605393913382, "LANTUS": 2.118410752769286, "LEVEMIR": 19.205853969283893, "NEXAVAR": 1.05066620284357, "OLANZAPINE": 1.86303763098994, "SOLIRIS": 7.786573897353309, "SPIKEVAX": 0.0814120011486265, "SUBOXONE": 10.712903288733242, "XOLAIR": 1.1316799740797758, "ZYPREXA": 1.3266885532896364, "null": 1.5410488843611934}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9596.json
new file mode 100644
index 00000000000..eeb1c21d0fa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9596.json
@@ -0,0 +1 @@
+{"CHAMPIX": 10.136151290194698, "CICLOSPORIN": 3.3268379744040013, "COMIRNATY": 0.3160112547968481, "GALAFOLD": 171.6906000939662, "IBRANCE": 2.1845636954997434, "LOPINAVIR": 295.22224298423896, "LYRICA": 7.159491399975495, "REVATIO": 18.878108223792363, "SPIKEVAX": 0.1830539989594987, "STIVARGA": 8.243145150574604, "SUBOXONE": 3.794540152470388, "SUTENT": 1.272701053815186, "VAXZEVRIA": 0.2862975555813165, "VIAGRA": 16.21813189710212, "XELJANZ": 11.384730756368793, "XOFIGO": 25.724739474041545, "XYREM": 18.91428706978631, "null": 0.7627492776539958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9597.json
new file mode 100644
index 00000000000..a6f9c30b082
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9597.json
@@ -0,0 +1 @@
+{"COMIRNATY": 2.86742168050024, "SPIKEVAX": 1.0267257339965472, "null": 0.349218568869744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9598.json
new file mode 100644
index 00000000000..759bd853695
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9598.json
@@ -0,0 +1 @@
+{"BRINTELLIX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9599.json
new file mode 100644
index 00000000000..4abdd7ea39c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9599.json
@@ -0,0 +1 @@
+{"PAZOPANIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/96.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/96.json
index d976b9458f9..8b865fea882 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/96.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/96.json
@@ -1 +1 @@
-{"AMIKACIN": 89.69608075187472, "ZOSTAVAX": 11.877041876860147}
\ No newline at end of file
+{"COMIRNATY": 0.1691869263996031, "ICLUSIG": 46.27348328858969, "VAXZEVRIA": 0.6416310068440603, "null": 1.1294489857907912}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/960.json
index 2d26294d1ff..9e3d526fe5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/960.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/960.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 12.397029740644603, "ELIQUIS": 6.346513599081914, "ENTRESTO": 5.182148408632219, "LIXIANA": 25.243346701233516, "PLAVIX": 13.806287259183332, "SUTENT": 1.0396575433077966, "null": 1.734641871885991}
\ No newline at end of file
+{"COMIRNATY": 0.3412185888588083, "QUTENZA": 442.7458717345995, "SPIKEVAX": 1.1435092607094453, "VAXZEVRIA": 0.7028030532178101, "null": 3.641880562676099}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9600.json
new file mode 100644
index 00000000000..8856c6cb867
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9600.json
@@ -0,0 +1 @@
+{"null": 1.0520219589551332}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9601.json
new file mode 100644
index 00000000000..dc08d86215d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9601.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4442230007182978, "null": 0.9270549370730904}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9602.json
new file mode 100644
index 00000000000..dd93205f89c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9602.json
@@ -0,0 +1 @@
+{"STELARA": 7.183135100204376, "XELJANZ": 7.301578596903173, "null": 1.2001277502757262}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9603.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9603.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9604.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9604.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9605.json
new file mode 100644
index 00000000000..c5f43e09a8c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9605.json
@@ -0,0 +1 @@
+{"null": 11.855472382329772}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9606.json
new file mode 100644
index 00000000000..3dd251a3723
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9606.json
@@ -0,0 +1 @@
+{"KEPPRA": 7.20241699107861, "TESTOSTERONE": 179.91027558289872, "null": 2.690969605361543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9607.json
new file mode 100644
index 00000000000..c079965f928
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9607.json
@@ -0,0 +1 @@
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9608.json
new file mode 100644
index 00000000000..c079965f928
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9608.json
@@ -0,0 +1 @@
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9609.json
new file mode 100644
index 00000000000..3ab6b41bd9a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9609.json
@@ -0,0 +1 @@
+{"CLADRIBINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/961.json
index 4bdefcf536b..84c726e8e91 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/961.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/961.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 7.974073917778734, "ELIQUIS": 16.938764198578106}
\ No newline at end of file
+{"null": 4.1061343418925125}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9610.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9610.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9611.json
new file mode 100644
index 00000000000..6f67beeb341
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9611.json
@@ -0,0 +1 @@
+{"SOLIRIS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9612.json
new file mode 100644
index 00000000000..5e0950ccec3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9612.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.3272271287474966, "ABATACEPT": 0.8699541549545453, "ABILIFY": 4.788943680869141, "ADALIMUMAB": 2.086282777303257, "AMINOSALICYLIC": 4.032461398331105, "APROVEL": 3.8475409051214657, "ARAVA": 0.9226284399023535, "ARIPIPRAZOLE": 3.739111846796104, "ATRIPLA": 0.3931818435528876, "AZATHIOPRINE": 6.859078599897527, "BARACLUDE": 17.417996214854522, "BRINTELLIX": 6.605794418634002, "CELLCEPT": 0.920720496466974, "CIMZIA": 2.262256325760531, "COMBIVIR": 36.05845446688756, "COMIRNATY": 0.0659821783258225, "COSENTYX": 1.364296721042669, "DEXAMETHASONE": 2.014612834349552, "EFAVIRENZ": 12.897965922276812, "ELLAONE": 29.27504305039617, "ENTECAVIR": 18.56908384486345, "ENTYVIO": 49.53298732833145, "EPIVIR": 25.296389568421983, "EVRA": 12.377603435493102, "FENTANYL": 2.09669882964408, "HERCEPTIN": 4.709416242581648, "KEPPRA": 20.89976099228261, "LAMIVUDINE": 8.208890626529648, "LATUDA": 11.366393886709735, "LEMTRADA": 3.201617886173453, "LEVEMIR": 3.310246598265455, "LEVETIRACETAM": 8.080025611062089, "NEVIRAPINE": 24.456437645591368, "NORVIR": 19.068601939595894, "NOVORAPID": 2.499785876742554, "OLANZAPINE": 0.5650779131570135, "OPSUMIT": 0.8104871455518365, "PANTOPRAZOLE": 2.2399966754158616, "PEGASYS": 0.9209760749010332, "REYATAZ": 31.21522719821035, "ROACTEMRA": 1.8866111731685105, "SOLIRIS": 6.048436831128632, "SPIKEVAX": 0.0768023641584794, "STOCRIN": 36.640987519026496, "TAMIFLU": 4.257014348911788, "TOZINAMERAN": 0.103683607286437, "TRACLEER": 12.145529984146064, "TRUVADA": 1.69699330029499, "VAXZEVRIA": 0.1326044607865709, "VIMPAT": 2.668376815105756, "VIRAMUNE": 17.038471055472254, "VIREAD": 4.715708925021231, "ZERIT": 75.94110485622062, "null": 0.9636635359532204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9613.json
new file mode 100644
index 00000000000..63475786c19
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9613.json
@@ -0,0 +1 @@
+{"ELLAONE": 7627.940313052155, "null": 0.224378285137517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9614.json
new file mode 100644
index 00000000000..406e9d3e65e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9614.json
@@ -0,0 +1 @@
+{"PEGASYS": 12.513707960459236, "STELARA": 21.81298035436241, "TREMFYA": 96.6072963726104, "null": 0.3105256303692887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9615.json
new file mode 100644
index 00000000000..56cfd4caa24
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9615.json
@@ -0,0 +1 @@
+{"CIMZIA": 4.956866919101139, "KALETRA": 22.730537888467524, "KEPPRA": 8.592781965035686, "NORVIR": 58.381615201498406, "null": 1.6784401015129042}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9616.json
new file mode 100644
index 00000000000..1198bf9ef03
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9616.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.0306242851823152, "KEPPRA": 2.148254430603865, "null": 22.513545661893847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9617.json
new file mode 100644
index 00000000000..3595e1b7b21
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9617.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 21.34727233770498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9618.json
new file mode 100644
index 00000000000..4c5ffd12c5d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9618.json
@@ -0,0 +1 @@
+{"null": 0.9316421351246048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9619.json
new file mode 100644
index 00000000000..2034465ac32
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9619.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.473249192587538}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/962.json
index d348bff2409..3a15de9d28a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/962.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/962.json
@@ -1 +1 @@
-{"null": 1.7813829783242132}
\ No newline at end of file
+{"AVAMYS": 8.26284806705257, "COMIRNATY": 0.4242833966016182, "IBUPROFEN": 5.172364318192487, "KEPPRA": 2.3987763436716176, "KYMRIAH": 11.735727412449387, "MICARDIS": 16.188319255843574, "SPIKEVAX": 0.3407094818643865, "VAXZEVRIA": 0.2354932200667293, "null": 1.858710167337753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9620.json
new file mode 100644
index 00000000000..4eae046db3f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9620.json
@@ -0,0 +1 @@
+{"THALIDOMIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9621.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9621.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9622.json
new file mode 100644
index 00000000000..b01ff017d2b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9622.json
@@ -0,0 +1 @@
+{"null": 1.2090622314750106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9623.json
new file mode 100644
index 00000000000..34a3d7da7e9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9623.json
@@ -0,0 +1 @@
+{"EVRA": 158247.44099835248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9624.json
new file mode 100644
index 00000000000..1b3d01d8abe
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9624.json
@@ -0,0 +1 @@
+{"ATRIPLA": 5.340899951659084, "EFAVIRENZ": 419.6914731861493, "null": 1.1840183875764938}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9625.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9625.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9626.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9626.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9627.json
new file mode 100644
index 00000000000..15a42bde426
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9627.json
@@ -0,0 +1 @@
+{"null": 1.328998213790625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9628.json
new file mode 100644
index 00000000000..bb10d4894b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9628.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.7224884737423055, "ABILIFY": 6.544793346684963, "ACTRAPID": 4.277366932055089, "ADALIMUMAB": 0.0427137436922708, "AERIUS": 2.371543499196505, "AIMOVIG": 0.1887731770887915, "ALISKIREN": 1.3346582318382916, "ANTIBIOTICS": 4.105853583309913, "APIDRA": 2.435783809030747, "ARANESP": 1.3121433412553185, "ARAVA": 0.0786533690168639, "ARIPIPRAZOLE": 4.330123005810009, "ASPARAGINASE": 1.6292644448768543, "ATAZANAVIR": 2.870238485026556, "ATOSIBAN": 146.91602308270248, "AZATHIOPRINE": 10.31481390975923, "BETAFERON": 1.0353232941266983, "BIKTARVY": 1.8695344149333573, "BRIVARACETAM": 11.030295800604376, "BUDESONIDE": 1.395530865856138, "BUPIVACAINE": 14.970023769614745, "BUPRENORPHINE": 9.71590289697576, "BUVIDAL": 5.547184045710002, "CELLCEPT": 0.8639654015161379, "CHLORHEXIDINE": 11.610702158928223, "CICLOSPORIN": 4.894067285323268, "CIMZIA": 2.250197016815483, "CINACALCET": 26.46755019392775, "CLOPIDOGREL": 0.6447499309328777, "COMBIVIR": 17.031251404823326, "COMIRNATY": 0.0409901137933474, "CRIXIVAN": 5.249943410395293, "CYMBALTA": 0.8066056068235192, "CYTARABINE": 1.9281617224211167, "DARBEPOETIN": 8.687828480005768, "DARUNAVIR": 4.787319472087996, "DEXAMETHASONE": 8.89156052512726, "DEXMEDETOMIDINE": 17.384291923192563, "DOLUTEGRAVIR": 5.612270060079436, "DOXORUBICIN": 2.535419214095747, "ECULIZUMAB": 25.52749024781719, "EFAVIRENZ": 2.4924953161738097, "EMTRICITABINE": 6.460503986240286, "ENOXAPARIN": 10.36649488442397, "ENTYVIO": 0.5968149425576755, "EPIVIR": 7.312124600425434, "EPOETIN": 8.7230998826782, "ESOMEPRAZOLE": 2.4909328729846587, "EXFORGE": 0.5745395182688785, "FENTANYL": 11.974586530955964, "FILGRASTIM": 1.5119235267873707, "FORTOVASE": 15.677764662153026, "GARDASIL": 1.1158828762070092, "HUMALOG": 2.4918112493421383, "HUMAN": 5.066097186074768, "HYDROCORTISONE": 3.5104313441560904, "IBUPROFEN": 1.9451027563554375, "ILOPROST": 67.05813794476613, "INFLIXIMAB": 2.1480779669871533, "INSULATARD": 9.6183242895605, "INSULIN": 6.537352805092491, "INVIRASE": 5.12318380530117, "IRON": 17.626962712624604, "ISENTRESS": 12.082453096850964, "KAFTRIO": 0.9116751772815902, "KALETRA": 3.619660970891001, "KEPPRA": 4.636327062406334, "KIOVIG": 3.379669654386116, "KUVAN": 8.506722303138876, "LACOSAMIDE": 3.538757496942015, "LAMIVUDINE": 5.498225871974321, "LANTUS": 0.8051672586050793, "LATUDA": 0.6640789916831824, "LEVEMIR": 12.028899986426014, "LEVETIRACETAM": 2.3094888250466084, "LEVOFLOXACIN": 0.588402979150547, "MANNITOL": 8.642685573808313, "METHOTREXATE": 0.2941255972067157, "MIDAZOLAM": 2.110307346248842, "MIMPARA": 1.594072088743473, "MYCOPHENOLATE": 2.3976253249398645, "NORVIR": 7.138323483931827, "NOT": 0.9098701491964714, "NOVORAPID": 4.68519764820968, "OLANZAPINE": 0.5760103042857971, "OPIATES": 39.337907723587456, "OPSUMIT": 0.3695378120068642, "OSELTAMIVIR": 10.947227006336307, "PACLITAXEL": 2.2583734658357515, "PANTOPRAZOLE": 1.1012522235039015, "PEGINTRON": 0.1788723354024037, "PRIVIGEN": 0.566821437285516, "REMICADE": 7.191025423228614, "RITUXIMAB": 1.4747794708171331, "SILDENAFIL": 12.679871868393905, "SIMPONI": 0.4320067658643818, "SOLIRIS": 2.652551362143022, "SPIKEVAX": 0.0228464661620319, "STELARA": 0.9428938915153868, "SUBOXONE": 12.612305107115532, "SUFENTANIL": 2.173504966771082, "TACROLIMUS": 6.992214468985721, "TOZINAMERAN": 0.1044537056878968, "TRACLEER": 0.503481286589704, "TRACTOCILE": 118.04908072199056, "TRESIBA": 2.099053487149799, "TRUVADA": 0.1339940800393476, "VIMPAT": 1.0290017878813538, "VIRAMUNE": 2.8678991685492417, "XOLAIR": 1.2106271605599257, "ZYPREXA": 1.4137949697343926, "null": 1.7805110751657092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9629.json
new file mode 100644
index 00000000000..cd82e651062
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9629.json
@@ -0,0 +1 @@
+{"null": 1.238475077264254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/963.json
index 10736c5e999..66b69631af1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/963.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/963.json
@@ -1 +1 @@
-{"COSENTYX": 2.2490054255730696, "EYLEA": 7.002434719385906, "HUMALOG": 1.6414225272366003, "ZOSTAVAX": 9.390606771240536, "null": 1.0890828417288902}
\ No newline at end of file
+{"null": 1.1852302252440632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9630.json
new file mode 100644
index 00000000000..40d7024c794
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9630.json
@@ -0,0 +1 @@
+{"ABILIFY": 6.638622917125344, "ACTRAPID": 7.798892225614347, "AERIUS": 3.0066499867843164, "AIMOVIG": 0.4153741163147366, "AMBRISENTAN": 6.1744054254780325, "ARANESP": 1.4673794691133892, "ARIPIPRAZOLE": 12.10059830412037, "ATAZANAVIR": 6.811636044537971, "ATOSIBAN": 631.9486856443345, "AZATHIOPRINE": 13.07887991777015, "BIKTARVY": 3.368697788612041, "BRIVARACETAM": 24.3147215911612, "BUDESONIDE": 0.5524343753115293, "BUPIVACAINE": 17.039840627280874, "BUPRENORPHINE": 14.025992939408033, "CELLCEPT": 0.5739027096444425, "CHLORHEXIDINE": 12.18509396476181, "CICLOSPORIN": 2.1471278925954778, "CIMZIA": 4.609521765008836, "CINACALCET": 20.12054408455916, "CLOPIDOGREL": 0.3119374819300186, "COMBIVIR": 10.8441398054403, "COMIRNATY": 0.0330185608976532, "CORTICOSTEROIDS": 22.918067778130204, "CYMBALTA": 0.1882994634507118, "CYTARABINE": 12.853060264706691, "DARUNAVIR": 9.26322385850158, "DEXAMETHASONE": 7.758556214021527, "DEXMEDETOMIDINE": 22.995042803899363, "DUPILUMAB": 52.25794809196569, "EFAVIRENZ": 3.4151491307965967, "EMTRICITABINE": 10.735411485505155, "ENOXAPARIN": 6.690299099287812, "EPIVIR": 11.130256088603078, "EPOETIN": 14.321792496065203, "FENTANYL": 8.010107705697573, "HUMALOG": 0.291283136427201, "HUMAN": 2.3200932128313845, "HYDROCORTISONE": 6.506040444871801, "IBUPROFEN": 0.870125730182394, "ILOPROST": 100.909144764413, "INFLIXIMAB": 3.81408163964804, "INSULATARD": 10.524812983759936, "INSULIN": 5.360217621049917, "IRON": 6.633296134515385, "ISENTRESS": 10.99345150372856, "KALETRA": 2.710301706789437, "KEPPRA": 7.0933592943487085, "KIOVIG": 5.436984145381256, "LACOSAMIDE": 10.297646952277118, "LAMIVUDINE": 3.7358090888459534, "LANTUS": 0.4367577798120863, "LEVEMIR": 9.659672914885313, "LEVETIRACETAM": 3.328003682593172, "LOPINAVIR": 7.949720235856247, "MIDAZOLAM": 2.266586478328162, "MIMPARA": 5.409134156361651, "NORVIR": 9.566251248974568, "NOVORAPID": 2.7330393442680494, "OPSUMIT": 0.8772863583332224, "OSELTAMIVIR": 42.38847643028049, "PANTOPRAZOLE": 1.2330097489390557, "REMICADE": 5.77335135299074, "RITUXIMAB": 1.5642500694625574, "SILDENAFIL": 42.23440861178727, "SOLIRIS": 2.4612756984391195, "SPIKEVAX": 0.0235762199727667, "SPIRONOLACTONE": 3.4885240994097573, "STELARA": 0.5926359955947892, "SUBOXONE": 25.87609419684661, "TACROLIMUS": 3.789818494331719, "VIMPAT": 1.6632504728741986, "XOLAIR": 1.1347518611120178, "null": 0.9848310870775188}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9631.json
new file mode 100644
index 00000000000..c9ebd06db97
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9631.json
@@ -0,0 +1 @@
+{"VIAGRA": 53.27596748161916, "null": 3.86594695569077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9632.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9632.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9633.json
new file mode 100644
index 00000000000..d0bb331f6dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9633.json
@@ -0,0 +1 @@
+{"ABACAVIR": 2.6015549874251267, "ABILIFY": 3.40722504167456, "APTIVUS": 50.64353106010293, "ARIPIPRAZOLE": 1.5199922362775868, "AZATHIOPRINE": 20.26198376190649, "BUPRENORPHINE": 3.029869940054972, "CICLOSPORIN": 8.099859258558268, "COMBIVIR": 13.47592596315812, "COMIRNATY": 0.1116189622968898, "CYMBALTA": 0.6300768102665845, "DEXAMETHASONE": 3.748049970141838, "DOXORUBICIN": 4.6279261118858805, "ENOXAPARIN": 6.233900652516304, "FENTANYL": 3.5149937876281547, "GARDASIL": 2.631775490923829, "HUMALOG": 2.218272342325548, "HYDROCORTISONE": 4.044609075760741, "INSULIN": 1.809224028646411, "ISENTRESS": 22.61565144946711, "KALETRA": 4.942066518399148, "KEPPRA": 3.43729556576194, "LANTUS": 0.5907451577933895, "LEVEMIR": 3.1515315199709484, "NORVIR": 18.05163915933248, "OXYBUTYNIN": 10.622350016349966, "PANTOPRAZOLE": 8.189341740847231, "SPIKEVAX": 0.0992830037930294, "STELARA": 2.495150601327828, "SUBOXONE": 24.616421498791208, "TAMIFLU": 1.8844969038742168, "TOZINAMERAN": 0.1130140992940638, "TRACTOCILE": 55.9556496487921, "XOLAIR": 1.002480454276724, "null": 1.6009282134293192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9634.json
new file mode 100644
index 00000000000..8ed4b42f8d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9634.json
@@ -0,0 +1 @@
+{"BUSULFAN": 114.5139636956068, "COMIRNATY": 1.1040992379820656, "GARDASIL": 16.00694302108516, "SPIKEVAX": 0.5934526333324662, "TOZINAMERAN": 1.458872984244159, "VAXZEVRIA": 1.1230425304659533, "null": 0.4653008085517563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9635.json
new file mode 100644
index 00000000000..d216a221c02
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9635.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.697963956001738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9636.json
new file mode 100644
index 00000000000..d70fd065efa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9636.json
@@ -0,0 +1 @@
+{"null": 5.902975062663117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9637.json
new file mode 100644
index 00000000000..c0a6ecbfee5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9637.json
@@ -0,0 +1 @@
+{"ATAZANAVIR": 32.33386297130203, "ATOSIBAN": 124.85658155349412, "BUPRENORPHINE": 7.449047492269636, "CIMZIA": 2.793252679788289, "COMBIVIR": 31.29985680412729, "COMIRNATY": 0.1134913928071908, "EFAVIRENZ": 25.179919969416503, "EPIVIR": 17.51643184253225, "EPOETIN": 56.56878537110124, "GARDASIL": 2.2741795034101595, "ISENTRESS": 27.861011607992804, "KALETRA": 14.324163245206146, "LANTUS": 1.5144160545454202, "NORVIR": 36.794002436428336, "PEGASYS": 1.294887733006703, "SPIKEVAX": 0.0879726101241275, "SUBOXONE": 8.098139334715492, "TAMIFLU": 4.02042901331533, "null": 1.30528906632449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9638.json
new file mode 100644
index 00000000000..af6cbfa295a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9638.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 5.748375293512157, "COMIRNATY": 0.184847978394099, "CYMBALTA": 1.895209938894585, "SPIKEVAX": 0.1914369360495089, "SUBOXONE": 13.206352350209208, "null": 2.628859732246029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9639.json
new file mode 100644
index 00000000000..7e66b40fa3e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9639.json
@@ -0,0 +1 @@
+{"COMIRNATY": 3.9584206943682103, "SPIKEVAX": 0.935752617017518, "TOZINAMERAN": 6.27280509534854, "null": 0.2194810159877697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/964.json
index b6684bd65ac..29ef95e38fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/964.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/964.json
@@ -1 +1 @@
-{"ABATACEPT": 22.653366617450757, "ADALIMUMAB": 31.39548064847843, "AIMOVIG": 42.20960970134791, "APREMILAST": 59.4378117934347, "AVAMYS": 10.563219507758262, "LATUDA": 3.237365173149017, "OLANZAPINE": 1.6174874349376571, "RITUXIMAB": 1.1688741012994626}
\ No newline at end of file
+{"null": 8.776243808083176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9640.json
new file mode 100644
index 00000000000..40e4b5cfdab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9640.json
@@ -0,0 +1 @@
+{"COMIRNATY": 4.545982963253368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9641.json
new file mode 100644
index 00000000000..fdc4c758c90
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9641.json
@@ -0,0 +1 @@
+{"COMIRNATY": 8.840016958443771, "MODERNA": 3.7570987821666, "SPIKEVAX": 2.5743712548674136, "TOZINAMERAN": 3.8623488590802406, "VAXZEVRIA": 0.8138314736304401, "null": 0.0345686798380537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9642.json
new file mode 100644
index 00000000000..e1d4c989039
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9642.json
@@ -0,0 +1 @@
+{"COMIRNATY": 11.344913236170637, "MODERNA": 13.002946199411834, "SPIKEVAX": 2.1064536601124577, "TOZINAMERAN": 2.503938206148295, "VAXZEVRIA": 0.2954231837646191, "null": 0.1094397922187067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9643.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9643.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9644.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9644.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9645.json
new file mode 100644
index 00000000000..b67da99606b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9645.json
@@ -0,0 +1 @@
+{"ARAVA": 0.6854968984945569, "CLOPIDOGREL": 4.846135604642049, "COMIRNATY": 0.062374608909482, "ENTRESTO": 4.001117735199706, "FORXIGA": 10.31833635734904, "JARDIANCE": 6.896299462466815, "KEYTRUDA": 5.64994917623906, "null": 1.5874491509805744}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9646.json
new file mode 100644
index 00000000000..4bcc618ea7b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9646.json
@@ -0,0 +1 @@
+{"ABATACEPT": 33.715307282371825, "ARAVA": 9.149477968100078, "ENBREL": 19.65624519239521, "MEPOLIZUMAB": 26.90856146456372, "null": 0.5589725786929561}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9647.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9647.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9648.json
new file mode 100644
index 00000000000..a69846ea5de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9648.json
@@ -0,0 +1 @@
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9649.json
new file mode 100644
index 00000000000..1bc5140c572
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9649.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3358697349123941, "HUMALOG": 6.144242047071026, "ZOSTAVAX": 72.71929384441292, "null": 0.4759549637590911}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/965.json
index b0c183599b7..1c93d877847 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/965.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/965.json
@@ -1 +1 @@
-{"APIDRA": 2.9446450514647147, "APIXABAN": 10.909800337939425, "AUBAGIO": 1.0813620437239115, "AVANDAMET": 4.482629514624176, "AVANDIA": 3.3290183326233627, "AVASTIN": 2.172725269532234, "BENLYSTA": 1.179832164247954, "BEOVU": 35.17948017097839, "BEVACIZUMAB": 2.899225985783082, "BOSULIF": 1.6109695791739076, "BRAFTOVI": 1.414475088766271, "BROLUCIZUMAB": 40.06329091219243, "BUPRENORPHINE": 1.192820976055783, "BYDUREON": 1.0354454329362557, "CICLOSPORIN": 1.4424867262508625, "CRIXIVAN": 1.166740282181136, "DACLATASVIR": 2.910394317097917, "DESCOVY": 2.442932414071355, "EFAVIRENZ": 1.3055358361188758, "EVISTA": 1.4014283394904117, "EXFORGE": 1.3207925809427856, "EYLEA": 43.81685030614845, "GANCICLOVIR": 1.422340592981146, "GARDASIL": 1.4756946116141605, "HUMALOG": 12.932367505458654, "IBRANCE": 1.7750120937494132, "INCRUSE": 1.8317836363922315, "INSULIN": 3.0215172802751127, "INTELENCE": 3.709520722607151, "JARDIANCE": 2.200560377425919, "LANTUS": 9.949022010269813, "LEVEMIR": 4.996811570925369, "LUXTURNA": 29.528157804574704, "LYRICA": 1.2518131472989176, "MEKINIST": 2.3150491481420974, "METHOTREXATE": 1.0566276822299132, "MICARDIS": 1.075543248233276, "NAGLAZYME": 2.930696847597626, "NEVANAC": 5.224102944279429, "OXYBUTYNIN": 1.7054815729153343, "PEGASYS": 1.2573428912286189, "PLEGRIDY": 1.1550214422717755, "RAPAMUNE": 2.9933731814769478, "REVATIO": 1.150075225194309, "RITUXIMAB": 1.1677917277501082, "RYBELSUS": 1.2895575984447276, "SILDENAFIL": 2.77538486915733, "TAMIFLU": 1.2083095021811616, "TASIGNA": 1.0499533656128603, "TOBRAMYCIN": 3.5442191013587165, "TOUJEO": 5.665544494556956, "TOVIAZ": 2.255868560268788, "TOZINAMERAN": 1.1125335806261971, "TRELEGY": 2.049466158192442, "TRULICITY": 2.665281332803318, "UMECLIDINIUM": 4.949239319352478, "VFEND": 2.007358988849574, "VIAGRA": 13.731050790795852, "VICTOZA": 1.462580515965502, "XALKORI": 1.9705946555242209, "XELJANZ": 2.273259630781705, "ZOSTAVAX": 8.261004252476877, "null": 1.0519478369288489}
\ No newline at end of file
+{"null": 1.174616373878293}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9650.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9650.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9651.json
new file mode 100644
index 00000000000..14175c089f1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9651.json
@@ -0,0 +1 @@
+{"ABACAVIR": 53.5035246367101, "ABATACEPT": 1.5388486292787842, "ABILIFY": 14.963308792199156, "ADALIMUMAB": 2.649154763026727, "AERIUS": 2.6327121579447144, "APIXABAN": 0.2860760873784055, "APREMILAST": 3.014320009463184, "ARAVA": 0.6578645407360548, "ARIPIPRAZOLE": 11.667094273120467, "ATAZANAVIR": 4.219392227827703, "AVAMYS": 0.5617989788736643, "BRINTELLIX": 3.657579581639872, "BRIVARACETAM": 4.52465246155034, "BRIVIACT": 5.712132665153324, "BUPIVACAINE": 6.722360960423224, "BUPRENORPHINE": 2.332966420873178, "C1": 54.40658618686044, "CANCIDAS": 2.001241869493409, "CINRYZE": 24.101428144326384, "CIRCADIN": 11.727236751747808, "CLOPIDOGREL": 0.8574603614877513, "COSENTYX": 0.7600918911819283, "CUBICIN": 1.8413075439555, "CYMBALTA": 2.884642532235161, "EFIENT": 3.788697294503779, "ELIQUIS": 4.476204083143558, "ENBREL": 0.7645960240826074, "FENTANYL": 0.8771015586893096, "FIRDAPSE": 5.580106995554496, "FORSTEO": 0.4053772814906459, "HUMIRA": 0.7430957454560195, "IKERVIS": 42.16403842664547, "IPILIMUMAB": 3.019148756330173, "JANUMET": 0.6370608982837708, "JANUVIA": 0.8676714305077798, "KEPPRA": 2.183454912486244, "LACOSAMIDE": 1.977153121214298, "LATUDA": 4.176899015217927, "LEVETIRACETAM": 0.7253423031657679, "LEVOFLOXACIN": 0.7141362967308968, "LYRICA": 1.7020241666263167, "MICARDIS": 1.136924054467803, "NOXAFIL": 4.341061389787439, "OLANZAPINE": 6.758893329443827, "OPDIVO": 4.195065923211207, "PLAVIX": 4.575458672889964, "REVATIO": 6.408397397325239, "SPRYCEL": 0.8065808642075034, "SUBOXONE": 4.142519512561109, "SYCREST": 9.10113487826083, "TOVIAZ": 1.8795365706934564, "VFEND": 1.5858966089992406, "VIAGRA": 0.8046022615281563, "VIMPAT": 1.0696341496286728, "XELJANZ": 1.0869208807241428, "YERVOY": 32.797987113559344, "ZYPADHERA": 25.019653221165527, "ZYPREXA": 43.68725474392463, "null": 1.1357948209742053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9652.json
new file mode 100644
index 00000000000..a635bd423b8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9652.json
@@ -0,0 +1 @@
+{"ABATACEPT": 2.222214556680877, "ABILIFY": 6.376538326555682, "ADALIMUMAB": 5.617573005234, "AMINOSALICYLIC": 3.1467426373590417, "ANAKINRA": 15.906676272822873, "APIDRA": 1.0289536838313036, "APIXABAN": 0.7060366091411485, "ARAVA": 3.558710354193266, "BENLYSTA": 1.0632702447291478, "BRINTELLIX": 1.727436471341416, "BRUKINSA": 37.800265656865406, "CIMZIA": 0.8981396037431185, "CLOPIDOGREL": 3.1925396124730336, "ELIQUIS": 55.04538383858889, "ENBREL": 0.696897411104272, "ENTRESTO": 12.828336572077127, "ERLEADA": 8.501462338724695, "FAMPYRA": 17.55742788952833, "FEBUXOSTAT": 8.9209062405223, "GILENYA": 10.849328929140706, "INCRUSE": 4.582914788213763, "IPILIMUMAB": 4.603506628675699, "JANUMET": 0.8356165767267753, "LATUDA": 26.845203589340443, "LIXIANA": 2.2922989361270742, "LONSURF": 12.061890520799398, "NERLYNX": 70.74528973363854, "OBINUTUZUMAB": 59.929557590833554, "OPDIVO": 4.590715224437839, "PEMBROLIZUMAB": 3.812461611938893, "PLAVIX": 0.871379582357613, "PLEGRIDY": 2.39238349805812, "RUBRACA": 16.198406409227303, "SPINRAZA": 7.158483424727773, "SPRYCEL": 52.93167860462712, "VALSARTAN": 28.444418686658093, "VIMPAT": 2.582923215234883, "XARELTO": 4.39168114912845, "XELJANZ": 0.2799998194370769, "XTANDI": 15.400983405917302, "null": 0.3657782971696077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9653.json
new file mode 100644
index 00000000000..d0451840010
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9653.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 8.007116152330504, "CHAMPIX": 5.228148959205406, "CLOPIDOGREL": 2.602154607373573, "ELIQUIS": 0.8501037270047833, "FENTANYL": 3.9961244542285215, "HUMALOG": 1.4402214133295832, "JANUMET": 3.3291785622625736, "LYRICA": 2.697621022992174, "PREGABALIN": 31.051901020905557, "SAXENDA": 10.492383405543332, "SILDENAFIL": 14.762775935472376, "TESTOSTERONE": 22.59359349114965, "TRELEGY": 10.089143579205649, "TRUVADA": 0.694327528360267, "VIAGRA": 30.780490277612422, "XELJANZ": 1.1284152341891778, "null": 2.7975576879854622}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9654.json
new file mode 100644
index 00000000000..5af00a5df21
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9654.json
@@ -0,0 +1 @@
+{"null": 9.92744516030226}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9655.json
new file mode 100644
index 00000000000..5def5e82028
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9655.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 22.69939294368555, "null": 2.951766506062098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9656.json
new file mode 100644
index 00000000000..0c517e59b76
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9656.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.2526523861172007, "ADALIMUMAB": 0.2250335483368129, "AERIUS": 0.7535471158260498, "AIMOVIG": 0.5193605502894462, "APIDRA": 1.079218614214341, "APIXABAN": 0.2512322527615842, "APROVEL": 0.843569127078704, "ARAVA": 0.0214066422650457, "AVAMYS": 0.2189564475449637, "AVANDIA": 0.1589142928335836, "BEXSERO": 1.31347514459339, "BRILIQUE": 1.1591612051689666, "BRIMICA": 62.267975873994246, "BRINTELLIX": 0.6137406714525945, "BUDESONIDE": 0.1735741392567576, "BYDUREON": 0.4503804379313937, "BYETTA": 0.3804027213958517, "CERVARIX": 5.612881996941176, "CHAMPIX": 0.3941347003072448, "CLOPIDOGREL": 0.4318293648205539, "COAPROVEL": 0.5219655362096183, "COMIRNATY": 2.457391017552934, "CORTICOSTEROIDS": 4.854771962447388, "CYMBALTA": 0.604117070583111, "DEXAMETHASONE": 0.1398896380069669, "DULOXETINE": 0.5418692572033874, "ELIQUIS": 0.2357896040032506, "EMPAGLIFLOZIN": 4.06641024417524, "ENBREL": 0.1519941663297501, "ENTRESTO": 1.1113474521369529, "ENTYVIO": 0.2044851159743002, "ENZALUTAMIDE": 2.193068961348544, "EXFORGE": 0.3168514101638761, "FASENRA": 0.3470102038608001, "FASLODEX": 0.6457649517078816, "FENTANYL": 0.1391228722651799, "FLUCELVAX": 2.751092465083319, "FORSTEO": 0.9732127236598532, "FORXIGA": 0.2130961762962013, "GALVUS": 0.6863907236954381, "GARDASIL": 5.7534832119186845, "HARVONI": 0.5006515035470626, "HIZENTRA": 0.472714315886938, "HUMALOG": 1.148989457856316, "IBRANCE": 0.1271790601777371, "INCIVO": 0.9405012701100568, "INSULIN": 0.2065919574455216, "IRBESARTAN": 0.603611662889911, "IVABRADINE": 19.74648643544044, "JANUMET": 0.1671778719967008, "JANUVIA": 0.223127293122831, "JARDIANCE": 0.3407571135658097, "KALETRA": 0.2386342617843953, "KARVEA": 11.031226228445153, "KARVEZIDE": 6.236679600672139, "KEPPRA": 0.1618328939837078, "KEYTRUDA": 0.0879776270995801, "LANTUS": 0.8194157495491609, "LEVEMIR": 0.3851161275053932, "LEVOFLOXACIN": 0.2477058226536877, "LYRICA": 0.2981575714108203, "MEKINIST": 0.2575346536940707, "MENVEO": 5.491821028525964, "METHOTREXATE": 0.1781802894548716, "MICARDIS": 1.4789437881011052, "MICARDISPLUS": 8.445860528172176, "MMRVAXPRO": 1.3650749822789712, "MODERNA": 1.5830566662945806, "MULTAQ": 0.7111960574176883, "NEULASTA": 0.6858726114406742, "NIMENRIX": 5.41333610801312, "NOVONORM": 2.031940858440355, "NUCALA": 0.1530925605892144, "OCRELIZUMAB": 0.4964831405868518, "OPSUMIT": 1.13561811928649, "PEGASYS": 0.3306103462185235, "PEGINTRON": 0.2446665789510468, "PLAVIX": 0.4166410081850862, "PREVENAR": 2.008337150016915, "PRITORPLUS": 15.515070674962002, "PRIVIGEN": 0.5255484866470902, "QUTENZA": 2.39788887399838, "RANEXA": 1.7121289161320918, "RAPISCAN": 4.7424936056094, "REMICADE": 1.012700102818074, "REVATIO": 0.6780614646621022, "RITUXIMAB": 0.1738155005365168, "RIVAROXABAN": 1.602917513547265, "ROACTEMRA": 0.24206067822099, "SAXENDA": 0.550570428737936, "SHINGRIX": 0.565603352514288, "SILDENAFIL": 1.621155512675596, "SOLIRIS": 0.2252487740220471, "SOVALDI": 0.7193158169910054, "SPIKEVAX": 2.5155029723572717, "STELARA": 0.1282585272653983, "SUBOXONE": 0.1161716687720687, "SUTENT": 0.1744980326657731, "TICAGRELOR": 0.6645312593967211, "TOZINAMERAN": 1.6179359670835138, "TRACLEER": 0.695322085440593, "TRULICITY": 0.2172836780473638, "TWINRIX": 1.1170211616906092, "UROREC": 4.319022426315292, "VAXZEVRIA": 0.8890365022060627, "VIAGRA": 0.8043281556211639, "XARELTO": 0.3894013471576549, "XELJANZ": 0.1262440257594826, "XOLAIR": 0.5220479586286801, "XTANDI": 0.1052160915290275, "ZOSTAVAX": 0.3336558771778139, "ZYPADHERA": 1.152536872800983, "ZYPREXA": 0.3174258237239875, "null": 0.9107659533433216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9657.json
new file mode 100644
index 00000000000..95df567e2c4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9657.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.6520627912870607, "HYDROCORTISONE": 74.16520319488252, "null": 0.8168716231191817}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9658.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9658.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9659.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9659.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/966.json
index 624170e33ad..9c4ef8f8f1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/966.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/966.json
@@ -1 +1 @@
-{"null": 1.731601702195374}
\ No newline at end of file
+{"null": 17.872197671562763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9660.json
new file mode 100644
index 00000000000..d2489fa6943
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9660.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 8.95496103338074, "ATRIPLA": 0.2589795981300333, "COMIRNATY": 0.0595684507371485, "OLANZAPINE": 26.89343438106261, "RISPERIDONE": 54.40247395563022, "SILDENAFIL": 52.59086758151312, "SUBOXONE": 2.591233594320881, "VAXZEVRIA": 0.064909185833316, "VIAGRA": 134.18168756080345, "ZYPREXA": 12.411333828450598, "null": 1.5304217956086636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9661.json
new file mode 100644
index 00000000000..b1e1418a2ed
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9661.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 25.61300630511453, "KEYTRUDA": 18.042306701863144, "NOXAFIL": 124.51802954776834, "OPDIVO": 35.38583373398441, "POSACONAZOLE": 333.4399540432499, "null": 0.2082027877196588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9662.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9662.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9663.json
new file mode 100644
index 00000000000..0a8d9237581
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9663.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3732139346100001, "OCALIVA": 131.2628631456531, "null": 1.0307792616273903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9664.json
new file mode 100644
index 00000000000..c079965f928
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9664.json
@@ -0,0 +1 @@
+{"CYTARABINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9665.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9665.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9666.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9666.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9667.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9667.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9668.json
new file mode 100644
index 00000000000..20cb3a6fbb3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9668.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 2.3434763012890563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9669.json
new file mode 100644
index 00000000000..aa73215f425
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9669.json
@@ -0,0 +1 @@
+{"null": 1.9652740731976104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/967.json
index 370d9e1522f..b9283cdc068 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/967.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/967.json
@@ -1 +1 @@
-{"CICLOSPORIN": 13.576604721972078, "null": 1.5093776788755695}
\ No newline at end of file
+{"COMIRNATY": 0.2204754152445748, "CYMBALTA": 5.193136571394251, "null": 1.2166477608223327}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9670.json
new file mode 100644
index 00000000000..8679cb18d1e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9670.json
@@ -0,0 +1 @@
+{"ENTRESTO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9671.json
new file mode 100644
index 00000000000..e9ac32df010
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9671.json
@@ -0,0 +1 @@
+{"BUSULFAN": 400.6407157717903, "null": 0.557465518305392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9672.json
new file mode 100644
index 00000000000..0c8aeff523f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9672.json
@@ -0,0 +1 @@
+{"IPILIMUMAB": 55.39933377858444, "KEYTRUDA": 14.763028292554106, "OPDIVO": 32.870005717940174, "PEMBROLIZUMAB": 87.02433046204894, "SUTENT": 5.187849881936481, "null": 0.4239531222073237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9673.json
new file mode 100644
index 00000000000..328a3ecdf2e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9673.json
@@ -0,0 +1 @@
+{"YESCARTA": 376.71858990274416}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9674.json
new file mode 100644
index 00000000000..ab9942bdc32
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9674.json
@@ -0,0 +1 @@
+{"YESCARTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9675.json
new file mode 100644
index 00000000000..fc593f89c09
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9675.json
@@ -0,0 +1 @@
+{"JAKAVI": 400.3402440581692, "RUXOLITINIB": 453.3999335105938, "null": 0.1597895696882565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9676.json
new file mode 100644
index 00000000000..d2af41a2b6d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9676.json
@@ -0,0 +1 @@
+{"FAMPYRA": 614.6092962228823, "null": 0.3111599477039508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9677.json
new file mode 100644
index 00000000000..39c018c9dff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9677.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.320051721914654, "SPIKEVAX": 1.6015022357931343, "TOZINAMERAN": 2.261330537078811, "VAXZEVRIA": 8.271816248786717, "null": 0.0922402116706217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9678.json
new file mode 100644
index 00000000000..188a75221bf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9678.json
@@ -0,0 +1 @@
+{"ERLEADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9679.json
new file mode 100644
index 00000000000..472340840a2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9679.json
@@ -0,0 +1 @@
+{"null": 0.8277566403541591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/968.json
index b767ec6dbed..6025aceafff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/968.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/968.json
@@ -1 +1 @@
-{"AERIUS": 5.960531138311021, "AFLIBERCEPT": 28.746271098669222, "APIDRA": 1.623036696693693, "AVASTIN": 2.874154525701481, "BEOVU": 44.23872226447951, "BROLUCIZUMAB": 30.42786773225056, "CHAMPIX": 2.712778228002888, "CICLOSPORIN": 1.245294185279046, "EYLEA": 252.2157695337441, "GARDASIL": 3.7372711912742287, "HUMALOG": 2.1680635879104875, "JETREA": 63.62272212748079, "PEGASYS": 1.1759556450154878, "PEGINTRON": 1.2386963471412618, "TRELEGY": 3.109983849750288, "TRULICITY": 1.3516257435309045, "VFEND": 2.4104147160362044, "VIAGRA": 7.056607911421479}
\ No newline at end of file
+{"BUPIVACAINE": 122.62714978821008, "FENTANYL": 14.479291842596162, "SPINRAZA": 96.45144110812238, "null": 1.9116623350956008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9680.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9680.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9681.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9681.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9682.json
new file mode 100644
index 00000000000..1a0fa2cdf25
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9682.json
@@ -0,0 +1 @@
+{"BRIDION": 51.024201046635234, "CELSENTRI": 147.42765613363318, "COMIRNATY": 0.3634358428237394, "FENTANYL": 14.71202713907429, "ICLUSIG": 34.87955655555459, "RELVAR": 44.69007450243696, "SPIKEVAX": 0.1617440644382793, "null": 1.5427959045150117}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9683.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9683.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9684.json
new file mode 100644
index 00000000000..35baee551af
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9684.json
@@ -0,0 +1 @@
+{"SPIKEVAX": 19.25478310735708}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9685.json
new file mode 100644
index 00000000000..7d2ec926818
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9685.json
@@ -0,0 +1 @@
+{"null": 0.4742600636610668}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9686.json
new file mode 100644
index 00000000000..fbf9f270773
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9686.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.0782839641585622, "CYTARABINE": 7.938607581413303, "KEYTRUDA": 4.277397947222581, "LEMTRADA": 18.293932959292068, "LEVOFLOXACIN": 5.824382344895901, "SOLIRIS": 7.35630632121839, "SPIKEVAX": 0.3716844390188995, "VORICONAZOLE": 28.95326954922581, "null": 0.7799475356681506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9687.json
new file mode 100644
index 00000000000..14cb8df51c1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9687.json
@@ -0,0 +1 @@
+{"SPINRAZA": 278.9977731143591, "null": 1.8010611399288314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9688.json
new file mode 100644
index 00000000000..d5e41213117
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9688.json
@@ -0,0 +1 @@
+{"BENLYSTA": 5.727665115750488, "ELIQUIS": 1.1494154015486877, "ESMYA": 122.33656821287612, "FENTANYL": 5.278665860033134, "HUMALOG": 1.967448501846644, "OPSUMIT": 8.668708634681412, "PEGASYS": 2.394694919680528, "SPINRAZA": 72.53106069592043, "TREMFYA": 16.047691533996204, "null": 1.363657176468441}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9689.json
new file mode 100644
index 00000000000..ded3c7de253
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9689.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 4.165006565722893, "null": 0.3884546592643642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/969.json
index e92cd5c5738..b1e24e03e74 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/969.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/969.json
@@ -1 +1 @@
-{"APIDRA": 6.007833031212383, "AUBAGIO": 1.9110991234850967, "AVANDIA": 1.789854954876147, "AVASTIN": 3.184626907555024, "BEOVU": 24.55406213144068, "BYDUREON": 1.5464262278078391, "ELIQUIS": 1.1605117946058956, "EVISTA": 4.39881776632864, "EYLEA": 144.42827962924525, "HUMALOG": 11.997009446823066, "ICLUSIG": 5.637633234211379, "INSULIN": 2.505773392245206, "JANUMET": 1.5505302722816934, "JARDIANCE": 1.2652619941819792, "LANTUS": 9.289603944321792, "LEVEMIR": 5.340982813071396, "MEKINIST": 2.274405063755457, "NEVANAC": 10.516404783580237, "PEGASYS": 1.1574213202269317, "PEGINTRON": 1.7010172017240754, "PLAVIX": 1.344010563665861, "PLEGRIDY": 2.495659992284561, "REVATIO": 1.6060031373072634, "ROACTEMRA": 1.1270112607256189, "SILDENAFIL": 2.292071863349082, "TRELEGY": 1.9130541409525408, "TRULICITY": 1.885270432190976, "VFEND": 1.1058024143470937, "VIAGRA": 14.988245792219963, "ZOSTAVAX": 4.404971921774035}
\ No newline at end of file
+{"BENZODIAZEPINES": 95.37984249360052, "BUPIVACAINE": 21.263933734614277, "CELECOXIB": 8.565377256697056, "CICLOSPORIN": 2.022068822238255, "CLOPIDOGREL": 1.2795769801509225, "COMIRNATY": 0.3425388643415391, "ESOMEPRAZOLE": 27.86565535883756, "FENTANYL": 6.639725212349458, "GARDASIL": 4.340270932646788, "IBUPROFEN": 3.50762368398444, "INSULIN": 6.105580091183346, "MIDAZOLAM": 6.259141874267348, "NUCALA": 2.728237260225613, "OLANZAPINE": 3.112970875790788, "SHINGRIX": 2.4799171088027743, "SPIKEVAX": 0.1668479216536965, "TOZINAMERAN": 0.4319592388366638, "TWINRIX": 6.4112930980695575, "VAXZEVRIA": 0.4775339066225318, "ZOSTAVAX": 1.1582542855903029, "null": 2.1167572041531395}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9690.json
new file mode 100644
index 00000000000..bf0ab20c3ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9690.json
@@ -0,0 +1 @@
+{"APIXABAN": 2.521347593051906, "BRILIQUE": 14.536229663335472, "CLOPIDOGREL": 18.231333611323365, "ELIQUIS": 19.30435305472116, "ENOXAPARIN": 19.80189911359619, "ESMYA": 30.69483207240664, "FEBUXOSTAT": 48.5525773713977, "HEMLIBRA": 33.57126784887463, "PLAVIX": 9.986673642058348, "RITUXIMAB": 4.98749950496952, "XARELTO": 17.40844868134598, "null": 1.3922354719929757}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9691.json
new file mode 100644
index 00000000000..4af153448d2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9691.json
@@ -0,0 +1 @@
+{"SPINRAZA": 469.6356570752501, "null": 0.5790785496784607}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9692.json
new file mode 100644
index 00000000000..d4a82da4229
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9692.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": 13.546330331869122, "FENTANYL": 68.09669564074585, "SUFENTANIL": 104.79014404852744, "null": 2.4549746061323043}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9693.json
new file mode 100644
index 00000000000..c386fb11b1b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9693.json
@@ -0,0 +1 @@
+{"BRIDION": 60.397401222571, "DEXAMETHASONE": 40.91062644354162, "FENTANYL": 78.93909269323471, "SPINRAZA": 191.43637376659936, "VAXZEVRIA": 0.7439645998016797, "null": 0.3740713753451217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9694.json
new file mode 100644
index 00000000000..8d1b6c016f6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9694.json
@@ -0,0 +1 @@
+{"ACLASTA": 28.83017076200957, "ADALIMUMAB": 20.613889272672285, "AMINOSALICYLIC": 39.64681039436218, "AVAMYS": 51.67119098351181, "BENLYSTA": 1.219664920672056, "BUDESONIDE": 61.95597092553348, "BUPIVACAINE": 3.299003172759335, "BUPRENORPHINE": 2.1642773954404824, "BYETTA": 1.6581784995000068, "CABOMETYX": 1.7420717943040742, "CIMZIA": 2.864659499329008, "COMIRNATY": 0.0112971395830476, "COSENTYX": 0.5123999498068998, "ELIQUIS": 1.4313284886457427, "ENBREL": 0.518313746254371, "ENTYVIO": 1.0353014289778046, "FASLODEX": 1.386379264722641, "FENTANYL": 2.670741101758068, "FORSTEO": 0.9061504558938426, "HUMALOG": 1.396705223335639, "HUMIRA": 4.235908062788276, "IBRANCE": 0.3457778281632678, "KEYTRUDA": 0.5473170423354392, "OMALIZUMAB": 0.9474794205092252, "PREGABALIN": 28.24629973648908, "SIMPONI": 1.070352403746283, "SOLIRIS": 1.061590998089712, "SPINRAZA": 120.87952076780572, "SUBOXONE": 13.969368258522453, "SUTENT": 0.5495449867998875, "VAXZEVRIA": 0.0450391169311036, "XELJANZ": 0.7249467213529147, "null": 0.3444861290611654}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9695.json
new file mode 100644
index 00000000000..24e60349b59
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9695.json
@@ -0,0 +1 @@
+{"null": 2.822612585487926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9696.json
new file mode 100644
index 00000000000..a228b8f3a88
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9696.json
@@ -0,0 +1 @@
+{"null": 1.5473470056149368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9697.json
new file mode 100644
index 00000000000..73a651699d2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9697.json
@@ -0,0 +1 @@
+{"BRIDION": 94.78763841099264, "DEXAMETHASONE": 36.54461745657496, "FENTANYL": 66.99599896725982, "SPINRAZA": 231.11594451421843, "null": 0.5952992107655793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9698.json
new file mode 100644
index 00000000000..ab9942bdc32
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9698.json
@@ -0,0 +1 @@
+{"YESCARTA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9699.json
new file mode 100644
index 00000000000..cd57cca0d5f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9699.json
@@ -0,0 +1 @@
+{"FORSTEO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/97.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/97.json
index 5ed686d3417..c595565a0b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/97.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/97.json
@@ -1 +1 @@
-{"null": 1.0067924667284014}
\ No newline at end of file
+{"null": 4.019963153301754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/970.json
index 925ccdea3df..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/970.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/970.json
@@ -1 +1 @@
-{"ABATACEPT": 13.394261660132887, "ACETAMINOPHEN": 15.569127133051085, "ACTRAPID": 1.8889597828425475, "ADALIMUMAB": 10.413889187908827, "AIMOVIG": 1.107051619050752, "ALDARA": 1.5774866802258294, "AMINOSALICYLIC": 2.0876604707061373, "AP": 50.60769786611604, "APREMILAST": 1.2016594056727152, "APREPITANT": 20.85342885254644, "ARAVA": 5.228731849232858, "BENLYSTA": 1.0160145588353082, "BYDUREON": 1.3879279911137024, "CABOMETYX": 1.8912068381031384, "CAELYX": 1.5726595760326103, "CANCIDAS": 1.9275260155091736, "CASPOFUNGIN": 1.7491429842360573, "CHLORHEXIDINE": 23.25443792693571, "CICATRIZANTS": 44.187351627185386, "CIMZIA": 7.965048363957997, "COSENTYX": 1.5187922891462105, "COTELLIC": 1.763721771715074, "DULAGLUTIDE": 1.5104157390691744, "ENOXAPARIN": 1.1095586681158114, "EUCREAS": 5.564323440104054, "EVOLOCUMAB": 23.39029526963781, "FEBUXOSTAT": 1.4063641829556797, "FORTIMEL": 70.05679981979254, "GALVUS": 3.795626199092832, "GLIBENCLAMIDE": 1.2728431731383998, "HUMIRA": 1.0708705946050778, "HYDROCORTISONE": 1.5616293796886136, "IMATINIB": 1.2145272464287986, "IMIQUIMOD": 5.029351794573634, "INLYTA": 1.93101315190692, "KONTRASTMITTEL": 74.64098888771214, "LEFLUNOMIDE": 1.375866359491602, "MENVEO": 1.1772243820717805, "METFORMIN": 18.133870710081453, "MISOPROSTOL": 5.008849940659971, "MYCOPHENOLATE": 1.04368851160156, "NEXAVAR": 4.592003870250461, "OLYSIO": 1.9624948856943465, "OXYBUTYNIN": 1.3083801367639194, "PROTOPIC": 4.314045402314704, "QUTENZA": 6.566157019135596, "RITUXIMAB": 1.0825839094968248, "SHINGRIX": 8.610809653613563, "SIFROL": 1.0522937601097866, "SORAFENIB": 3.4120996548188627, "STIVARGA": 4.34699061045532, "SUFENTANIL": 1.2925167547356289, "SUTENT": 3.3221446835384087, "TAMIFLU": 1.2877842685349177, "VILDAGLIPTIN": 8.470375359176595, "VOTRIENT": 1.1016455789275283, "ZELBORAF": 2.6675400667231437, "ZOSTAVAX": 1.4555806577135777, "ZYCLARA": 3.5442575108053176, "null": 1.0093750700665391}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9700.json
new file mode 100644
index 00000000000..c6972da7e75
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9700.json
@@ -0,0 +1 @@
+{"AVASTIN": 2.571095925674812, "CIMZIA": 2.45641571138052, "COMIRNATY": 0.1995549645363317, "CYTARABINE": 4.743904605819446, "ENTYVIO": 8.525389287369626, "FENTANYL": 2.084811537441358, "HUMIRA": 3.0980058629307856, "INCIVO": 58.57944069348382, "JARDIANCE": 2.548563526524648, "NEXAVAR": 1.046997026089656, "PEGASYS": 6.765729653415421, "PEGINTERFERON": 13.737783149482118, "PEGINTRON": 2.199082126005491, "RIBAVIRIN": 4.497240026359802, "SIMPONI": 1.5503154763203215, "SPIKEVAX": 0.1905479575676954, "STELARA": 1.113600181303393, "STIVARGA": 5.255582445562452, "SUTENT": 6.404032749282061, "TOZINAMERAN": 0.2023188732967518, "VAXZEVRIA": 0.1660356817181543, "VOTRIENT": 3.1426266372805896, "null": 1.259779170534611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9701.json
new file mode 100644
index 00000000000..9fc1a320a5a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9701.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 20.476742087331782, "ALIGN": 260.373752025888, "AMINOSALICYLIC": 146.21761997883382, "AVAMYS": 75.74016770729976, "AZATHIOPRINE": 2.036318151180873, "BUDESONIDE": 109.50216566278873, "COMIRNATY": 0.0394467191420115, "ENTYVIO": 10.367150263375128, "HUMIRA": 2.849794287046338, "INCIVO": 3.2245793420937776, "PEGASYS": 0.295165835737908, "PREGABALIN": 39.93384210020158, "XELJANZ": 1.2848972330760122, "null": 0.1498193925530828}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9702.json
new file mode 100644
index 00000000000..155d727890c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9702.json
@@ -0,0 +1 @@
+{"TRIUMEQ": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9703.json
new file mode 100644
index 00000000000..f07a0f21c9a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9703.json
@@ -0,0 +1 @@
+{"SUTENT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9704.json
new file mode 100644
index 00000000000..54c97708021
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9704.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.4826461031024494, "null": 0.738145342373657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9705.json
new file mode 100644
index 00000000000..adf53716073
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9705.json
@@ -0,0 +1 @@
+{"STELARA": 52.2085891163475}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9706.json
new file mode 100644
index 00000000000..47c7bf06b18
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9706.json
@@ -0,0 +1 @@
+{"HUMALOG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9707.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9707.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9708.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9708.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9709.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9709.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/971.json
index cfbacd99abb..9ed96e3a06b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/971.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/971.json
@@ -1 +1 @@
-{"SUTENT": 6.372988206573382}
\ No newline at end of file
+{"SUBOXONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9710.json
new file mode 100644
index 00000000000..c6f4373270c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9710.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 14.705013653484956, "EVRA": 333.66787809081507, "FENTANYL": 3.927392111610036, "KENTERA": 266.19442500055175, "null": 11.529930077408094}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9711.json
new file mode 100644
index 00000000000..12d843dded3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9711.json
@@ -0,0 +1 @@
+{"AIMOVIG": 2.807089982971555, "COMIRNATY": 0.6623315770376508, "EVRA": 53.11866923087421, "FASLODEX": 2.782236681630487, "FENTANYL": 3.612466528828293, "FLUCELVAX": 27.66358741540768, "FORSTEO": 5.143637701479135, "GARDASIL": 3.547148327329185, "HUMALOG": 1.4470579202455562, "LANTUS": 1.7310539742382882, "PLEGRIDY": 6.099888023583092, "QUTENZA": 43.80814975471984, "SHINGRIX": 6.276064580275574, "SPIKEVAX": 0.5050898480689944, "TOZINAMERAN": 2.2809560498663406, "TRULICITY": 8.868154149359322, "VAXZEVRIA": 0.4603296919018837, "ZOSTAVAX": 1.7012033486580844, "ZYPADHERA": 7.380180241670926, "null": 1.8700003547403476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9712.json
new file mode 100644
index 00000000000..442bde4949c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9712.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 3.6009262160802407, "BEXSERO": 14.206238764152433, "BRIDION": 15.295254625854325, "BRINTELLIX": 3.7987937859196346, "BUDESONIDE": 1.3283983410760989, "BUPIVACAINE": 12.842102940388692, "BUPRENORPHINE": 1.3356211461799763, "BUSULFAN": 11.647684250870563, "CICLOSPORIN": 0.5555910287958157, "CIRCADIN": 237.60224187662067, "COMIRNATY": 0.204847469581727, "COSENTYX": 1.351922562706659, "CRESEMBA": 27.39448415324466, "DEXAMETHASONE": 0.8392530433387729, "DEXDOR": 90.26655160878968, "DEXMEDETOMIDINE": 72.59612084088424, "ENTYVIO": 6.084663510162923, "FENTANYL": 0.6653489423851026, "FYCOMPA": 6.763873098312874, "GARDASIL": 2.633318660205244, "HEMANGIOL": 229.77071380582444, "ICLUSIG": 15.700536603397218, "INFANRIX": 7.266874030610229, "LATUDA": 5.531422011277158, "LEVETIRACETAM": 3.3369634952941434, "MIDAZOLAM": 4.787728912960708, "MMRVAXPRO": 0.8311993947388041, "NIMENRIX": 2.834225076393344, "NOXAFIL": 9.057095832837096, "OLANZAPINE": 0.8318977399071339, "PREVENAR": 11.76949827751537, "PROPRANOLOL": 6.406986198235708, "ROTATEQ": 21.06347028043164, "SHINGRIX": 19.91674250024481, "SLENYTO": 129.40971429495238, "SPIKEVAX": 0.1827761661758643, "STELARA": 0.4723084555131029, "TOZINAMERAN": 0.3276695163398579, "TWINRIX": 16.19330497497042, "VAXZEVRIA": 0.0918447056620117, "ZOSTAVAX": 1.436607618341864, "null": 1.9501346497160768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9713.json
new file mode 100644
index 00000000000..fb75ac72c41
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9713.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 2.4766469037637515, "ABILIFY": 0.2159314830991157, "ACTRAPID": 3.961220174426101, "AIMOVIG": 0.7364701184481404, "APIDRA": 5.530831410867896, "APIXABAN": 0.7309190658591346, "APROVEL": 2.720537302767459, "BENLYSTA": 0.8501097500060827, "BIKTARVY": 0.5951005731469486, "BONVIVA": 4.1010948190622765, "BRIDION": 1.2365801318540577, "BRINTELLIX": 1.0733198756561388, "BUDESONIDE": 0.1751120023385624, "BUMETANIDE": 2.331426833016173, "BUPIVACAINE": 0.9662064018173916, "BUPRENORPHINE": 0.4434168289255769, "BYDUREON": 0.96735989559356, "BYETTA": 0.6000834127622027, "CELLCEPT": 0.2133183424910265, "CICLOSPORIN": 0.1539471011382291, "CIMZIA": 0.0989416184141224, "CLOPIDOGREL": 4.825370284041592, "COMIRNATY": 0.0987895372597179, "COSENTYX": 0.6616453960472418, "CUBICIN": 0.7816242150043438, "CYMBALTA": 0.088661122192211, "DAPTOMYCIN": 15.008285073008134, "DULOXETINE": 1.2716906282759803, "ELIQUIS": 0.9844005424108732, "EMEND": 2.0685045277070637, "EMPAGLIFLOZIN": 1.2501421196325968, "ENTYVIO": 0.8622766724866054, "ESMYA": 14.643964181496422, "ESOMEPRAZOLE": 1.4786012092896186, "EVRA": 3.2445641172422026, "EXJADE": 0.5834388341019368, "EYLEA": 0.4127819381106148, "FASENRA": 0.5827284667972982, "FASLODEX": 0.9091687821094016, "FENTANYL": 0.9362701114012824, "FORXIGA": 0.5759946894714286, "GARDASIL": 0.1685797356129391, "GLIBENCLAMIDE": 2.7117892714209537, "HUMALOG": 2.086902483046888, "IBRANCE": 0.1990402514161276, "IBUPROFEN": 1.7171244236392704, "INCRUSE": 1.2152376424678264, "INSULIN": 1.627147264461203, "IRBESARTAN": 1.9203855686454123, "JAKAVI": 0.4959513457334797, "JANUMET": 1.7914257117150445, "JANUVIA": 0.6670264712376933, "JARDIANCE": 0.1603679798055582, "KEPPRA": 1.4787181508096128, "LANTUS": 12.106435728373285, "LATUDA": 6.973960736260638, "LEVEMIR": 2.4700163347647024, "LEVETIRACETAM": 1.7059141775372018, "LEVODOPA": 2.643930047773691, "LEVOFLOXACIN": 0.3656296324687068, "LYRICA": 0.994840709985766, "MAVENCLAD": 2.092727515314078, "MEKINIST": 0.4324736659064845, "MENVEO": 1.4793398439291832, "MEPOLIZUMAB": 2.251539315190804, "METHOTREXATE": 0.2723983071645622, "MIDAZOLAM": 1.8682692775721617, "MULTAQ": 0.7748064784465024, "NAGLAZYME": 3.544226731207049, "NEULASTA": 0.5787127829824525, "NEVANAC": 11.697888956126745, "NIMENRIX": 0.8378985990721731, "NOT": 2.648768608787486, "NOVORAPID": 2.5163504669673995, "NOXAFIL": 2.075841694296448, "NUCALA": 0.2029472346054857, "OLANZAPINE": 0.7168999409559407, "OPSUMIT": 0.5059838261448626, "PEGASYS": 0.3761274019463497, "PEGINTRON": 0.4704868135952138, "PLAVIX": 1.3204074479421246, "PRASUGREL": 23.65607156817275, "ROACTEMRA": 1.4514062871030156, "SHINGRIX": 1.2761098779131823, "SIMPONI": 1.2902361318754831, "SPIKEVAX": 0.0872290469387187, "STALEVO": 1.8269026957950616, "STELARA": 0.1821849085210319, "TAMIFLU": 0.8228613857074463, "TICAGRELOR": 3.396168971554871, "TOUJEO": 1.8229195262947409, "TOVIAZ": 1.0627099593759517, "TOZINAMERAN": 0.0756426052510018, "TRACLEER": 0.4662836624675058, "TRELEGY": 0.4444911155290276, "TREMFYA": 0.6472872021869555, "UNSPECIFIED": 5.682380424538338, "VAXZEVRIA": 0.0793065144008332, "VFEND": 0.6641203155921068, "VIAGRA": 1.3967549406466424, "VIMPAT": 2.1302545740166714, "VOTRIENT": 0.8325946669737413, "XARELTO": 1.5692759109812342, "XELJANZ": 0.1714637608109867, "XOLAIR": 0.3420180281529431, "ZOSTAVAX": 0.1685895588543771, "null": 3.672894101554789}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9714.json
new file mode 100644
index 00000000000..2acf4461b7c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9714.json
@@ -0,0 +1 @@
+{"AIMOVIG": 7.403352505966575, "AVAMYS": 10.028872085878527, "EBIXA": 92.2203453366499, "EVENITY": 30.2334681074962, "IBRANCE": 4.686587609288159, "IBUPROFEN": 15.227805495879991, "MACITENTAN": 128.16032812845071, "XELJANZ": 3.620117921578466, "null": 1.7257027859655698}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9715.json
new file mode 100644
index 00000000000..8b330bf7b94
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9715.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1216545228858062, "TRELEGY": 18.564093742256343, "null": 3.8835113527655456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9716.json
new file mode 100644
index 00000000000..9dfaf69372e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9716.json
@@ -0,0 +1 @@
+{"FIASP": 483.9761109908679, "NOVORAPID": 16.300347206330887, "null": 3.226204072737748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9717.json
new file mode 100644
index 00000000000..ea90d89c054
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9717.json
@@ -0,0 +1 @@
+{"AERIUS": 6.883150497184475, "APROVEL": 5.2569617447089545, "AVAMYS": 2.9836212687277484, "AZATHIOPRINE": 2.41626660099607, "BEDAQUILINE": 3.0077993634137505, "BENLYSTA": 25.63064723453765, "BETMIGA": 7.985409058127021, "BRIVIACT": 27.22052828453979, "CHAMPIX": 5.336997095177058, "CIMZIA": 8.023202489502967, "COMTAN": 17.015426290426387, "COSENTYX": 0.690155515885935, "ELIQUIS": 0.3899087722288051, "ENTRESTO": 1.0788851324316406, "IKERVIS": 39.08392780175632, "JAKAVI": 1.086173162055369, "JANUMET": 2.6372203209680807, "JANUVIA": 1.37266190997588, "KEPPRA": 6.01034830171031, "KEYTRUDA": 0.8009852984153588, "LEVETIRACETAM": 1.257539558384981, "LONSURF": 42.75693475670063, "NEXAVAR": 0.602687841538727, "NUCALA": 9.033012350582178, "OMALIZUMAB": 2.810540385060881, "OZEMPIC": 16.386957945067024, "PEGINTRON": 0.6809622453775164, "PLAVIX": 0.3875380321531682, "SIMPONI": 3.237748449222335, "STELARA": 0.9006006241383397, "TREMFYA": 7.885848714305376, "VAXZEVRIA": 0.0186816022349598, "VIMPAT": 6.260828099343911, "XOLAIR": 0.6491595208669322, "XTANDI": 2.802395357476865, "null": 2.9883159865866835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9718.json
new file mode 100644
index 00000000000..b80e441dbdf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9718.json
@@ -0,0 +1 @@
+{"BIKTARVY": 29.42146536340325, "ELIQUIS": 4.027631887859181, "null": 3.0440422129639613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9719.json
new file mode 100644
index 00000000000..5bc9a5ccca8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9719.json
@@ -0,0 +1 @@
+{"null": 5.893245732311049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/972.json
index 448a01a0a64..d46c4a9f6e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/972.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/972.json
@@ -1 +1 @@
-{"ANAKINRA": 32.52902958506136, "METFORMIN": 449.7576783969333, "TAMIFLU": 10.521377997928758, "null": 2.046410553472152}
\ No newline at end of file
+{"null": 0.6800081021864846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9720.json
new file mode 100644
index 00000000000..ce03faa843b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9720.json
@@ -0,0 +1 @@
+{"null": 28.39036076822111}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9721.json
new file mode 100644
index 00000000000..975479a2cd8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9721.json
@@ -0,0 +1 @@
+{"null": 3.4551740517825604}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9722.json
new file mode 100644
index 00000000000..112e289b5d9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9722.json
@@ -0,0 +1 @@
+{"null": 7.224155163960526}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9723.json
new file mode 100644
index 00000000000..31ff7263c7e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9723.json
@@ -0,0 +1 @@
+{"null": 6.111017718600995}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9724.json
new file mode 100644
index 00000000000..877cdea1982
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9724.json
@@ -0,0 +1 @@
+{"COAPROVEL": 14.577141390268164, "COMIRNATY": 0.0342308112537806, "ELIQUIS": 0.940375405152914, "EXFORGE": 6.306453795668079, "FIASP": 60.53769089424682, "JANUMET": 5.025908616631675, "NEVANAC": 77.60008461597022, "NOVORAPID": 8.002120466800525, "VELTASSA": 27.22284756317718, "VICTOZA": 6.473977193714279, "null": 4.22051478933999}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9725.json
new file mode 100644
index 00000000000..04e690db54c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9725.json
@@ -0,0 +1 @@
+{"null": 4.651981107894165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9726.json
new file mode 100644
index 00000000000..acca1489c00
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9726.json
@@ -0,0 +1 @@
+{"AIMOVIG": 23.801132845670423, "LEVEMIR": 20.145637157462776, "OLANZAPINE": 14.087881708873276, "SAXENDA": 12.65069974537242, "null": 1.842800767574896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9727.json
new file mode 100644
index 00000000000..4d06b157242
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9727.json
@@ -0,0 +1 @@
+{"ABASAGLAR": 1.4588680516119032, "ADEFOVIR": 22.58273994844667, "ANORO": 8.609315683185786, "APIDRA": 8.970029325602935, "AVAMYS": 6.142083189838575, "BENLYSTA": 4.982124344830921, "BUDESONIDE": 0.3561932989869179, "CLOPIDOGREL": 0.2625437083716939, "COMTAN": 6.956087761267162, "DEXAMETHASONE": 0.5070970825030403, "EVRA": 35.10255332432735, "FENTANYL": 0.3005547257683227, "HEPSERA": 3.57557203930012, "HUMALOG": 0.6838137635674756, "INCRUSE": 12.419809605101712, "INFERGEN": 19.630874306222, "INSULIN": 1.7005092476723789, "INSUMAN": 8.109223304435012, "INTEGRILIN": 4.992649438773675, "JANUMET": 0.2662004487695845, "KENTERA": 13.701573838435705, "KEPPRA": 0.9211955189480604, "LANTUS": 15.814757523840088, "LEVEMIR": 0.4130241353083258, "MMRVAXPRO": 0.6794909378674231, "MULTAQ": 0.8318805438676309, "NIMENRIX": 1.041031856338745, "NOVORAPID": 1.017605467117804, "NUCALA": 3.6130956203232474, "OLANZAPINE": 0.1802431828542691, "PEGASYS": 0.1492055560842642, "PEGINTRON": 0.7452398318074392, "PLAVIX": 0.6541720658693267, "RELVAR": 30.22467662418756, "REVINTY": 50.18569025613216, "ROACTEMRA": 1.0311622649696353, "SHINGRIX": 0.764635645824555, "SIMPONI": 1.0236709171375593, "SOVALDI": 2.159330908377829, "STALEVO": 20.89472713737045, "STELARA": 0.8556207848837895, "TRELEGY": 20.81137847643869, "TREMFYA": 3.361230663683683, "TWINRIX": 10.298596695916508, "VIAGRA": 1.1159145289994576, "XOLAIR": 0.2063916946355161, "null": 5.604779850910846}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9728.json
new file mode 100644
index 00000000000..82075a7bdac
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9728.json
@@ -0,0 +1 @@
+{"null": 4.289127571315924}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9729.json
new file mode 100644
index 00000000000..ec7b0edb47a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9729.json
@@ -0,0 +1 @@
+{"null": 2.838822608525758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/973.json
index e0942f72557..5648630ef53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/973.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/973.json
@@ -1 +1 @@
-{"null": 1.1422885138152594}
\ No newline at end of file
+{"GARDASIL": 4.486955127273264, "KEPPRA": 8.754358791036903, "null": 4.286603606573956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9730.json
new file mode 100644
index 00000000000..368dabd69a8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9730.json
@@ -0,0 +1 @@
+{"LEVEMIR": 17.111884658031975, "NEVANAC": 141.15257464816798, "NOVORAPID": 267.41556891083013, "null": 2.2138585110476297}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9731.json
new file mode 100644
index 00000000000..3e635094d03
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9731.json
@@ -0,0 +1 @@
+{"null": 2.609425135211878}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9732.json
new file mode 100644
index 00000000000..4ae6d6f2150
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9732.json
@@ -0,0 +1 @@
+{"EYLEA": 11.975743672888322, "SILDENAFIL": 122.25307621397302, "null": 3.402512114962458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9733.json
new file mode 100644
index 00000000000..3b18caf36d6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9733.json
@@ -0,0 +1 @@
+{"null": 20.425481095307067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9734.json
new file mode 100644
index 00000000000..cfb0e1dbc60
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9734.json
@@ -0,0 +1 @@
+{"COAPROVEL": 407.5192329439657, "null": 4.089133988081547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9735.json
new file mode 100644
index 00000000000..ea59704a2ae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9735.json
@@ -0,0 +1 @@
+{"HUMIRA": 19.310051257051537, "MIDAZOLAM": 44.26581189268449, "SPIKEVAX": 0.4962870912235497, "null": 2.3610043328185246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9736.json
new file mode 100644
index 00000000000..7ce4aded616
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9736.json
@@ -0,0 +1 @@
+{"null": 0.7507753524980778}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9737.json
new file mode 100644
index 00000000000..3e9cdda28af
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9737.json
@@ -0,0 +1 @@
+{"FENTANYL": 13.166813912993192, "LANTUS": 4.233143513894837, "PEGASYS": 2.4270704554170552, "PLAVIX": 24.48307202776711, "SILDENAFIL": 88.95473527871532, "VIAGRA": 11.3709334368447, "null": 2.1411885394512087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9738.json
new file mode 100644
index 00000000000..6c1f2c23823
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9738.json
@@ -0,0 +1 @@
+{"NEVANAC": 183.744377120215, "null": 9.259203723503918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9739.json
new file mode 100644
index 00000000000..c736f4a642a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9739.json
@@ -0,0 +1 @@
+{"FIASP": 192.4916176253385, "null": 5.274511895410337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/974.json
index abd9c33c0b4..48499f339da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/974.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/974.json
@@ -1 +1 @@
-{"null": 2.158702033383775}
\ No newline at end of file
+{"GARDASIL": 17.059728529030046, "null": 3.6551148810960665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9740.json
new file mode 100644
index 00000000000..c6c7b3c1a51
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9740.json
@@ -0,0 +1 @@
+{"null": 3.091661048238552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9741.json
new file mode 100644
index 00000000000..73d9f50a832
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9741.json
@@ -0,0 +1 @@
+{"null": 3.3427562765777976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9742.json
new file mode 100644
index 00000000000..5f51e88231d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9742.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.5706226982843818, "ACE": 40.20452458043525, "ANORO": 3.1323630042090533, "APIDRA": 2.1698423549050143, "ARAVA": 0.1382008667613642, "BYDUREON": 1.8737622948522312, "BYETTA": 1.1053935962952095, "CHAMPIX": 0.467741322640338, "CLOPIDOGREL": 1.3955346715785104, "CYMBALTA": 0.2622895824728518, "DAPTOMYCIN": 42.9960251449162, "ELIQUIS": 1.360588029262905, "ENTRESTO": 0.8663407566487672, "ENTYVIO": 2.68939055319414, "FIASP": 4.509962676687867, "FLUTICASONE": 30.38988706625284, "GARDASIL": 0.8615455066795452, "HUMALOG": 6.752269901843565, "IBRANCE": 4.094948278041528, "INCRUSE": 5.543423532013192, "INSULIN": 1.1370396967389702, "JANUMET": 2.420640120236335, "JARDIANCE": 0.4239978517342224, "JEVTANA": 6.758245194668755, "KEPPRA": 1.7827947339851062, "LANTUS": 1.4800282968570206, "LEVEMIR": 4.630371690540557, "LEVETIRACETAM": 0.9050286168747366, "NOVOMIX": 39.40436118860804, "NOVORAPID": 2.2245701272421683, "OLANZAPINE": 0.7377306223785596, "PANTOPRAZOLE": 1.7381542951331337, "RAPAMUNE": 3.1038582586778425, "RELVAR": 5.722550759897726, "REVATIO": 2.405952606024619, "RINVOQ": 1.1228087099237545, "SPIKEVAX": 0.0381381391990997, "STELARA": 0.6375842377902016, "SUBOXONE": 1.386416582963569, "SUTENT": 1.1273426580142831, "TAMIFLU": 1.2108172192582218, "TOUJEO": 2.7433617618824675, "TOVIAZ": 5.17099796717938, "TRELEGY": 4.223488242024546, "TRESIBA": 5.749580509544384, "VAXZEVRIA": 0.0202877049401384, "VEMLIDY": 16.39437735989556, "VFEND": 2.652762511189472, "VIAGRA": 3.609722227177732, "XELJANZ": 4.141014331122789, "null": 3.191112432935244}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9743.json
new file mode 100644
index 00000000000..58f7ae5bcae
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9743.json
@@ -0,0 +1 @@
+{"IBRANCE": 5.771184762573596, "XELJANZ": 10.823003110700968, "null": 2.525188482766702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9744.json
new file mode 100644
index 00000000000..3c744f3f3de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9744.json
@@ -0,0 +1 @@
+{"CIMZIA": 13.238677210405918, "FASENRA": 43.49793695450678, "null": 1.7603230773150238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9745.json
new file mode 100644
index 00000000000..ae5faa9dcfa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9745.json
@@ -0,0 +1 @@
+{"null": 3.089379857163957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9746.json
new file mode 100644
index 00000000000..27355f7c816
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9746.json
@@ -0,0 +1 @@
+{"null": 5.54779229845945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9747.json
new file mode 100644
index 00000000000..030666f2ec4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9747.json
@@ -0,0 +1 @@
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9748.json
new file mode 100644
index 00000000000..3560ee23297
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9748.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9749.json
new file mode 100644
index 00000000000..e91ba3ba7d4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9749.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/975.json
index 23b055efad1..13717b3c609 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/975.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/975.json
@@ -1 +1 @@
-{"null": 3.77657001277882}
\ No newline at end of file
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"TWINRIX": 0.6724908058866265, "VALSARTAN": 1.4028763456391111, "VAXZEVRIA": 0.5160423049184285, "VFEND": 0.9791131346806086, "VIAGRA": 1.447127081957264, "VICTOZA": 0.4909257605689906, "VIMPAT": 1.670532345151201, "VORICONAZOLE": 0.587183006012584, "VOTRIENT": 0.285712914291696, "XARELTO": 0.5968993801702298, "XELJANZ": 0.3090183384603187, "XOLAIR": 0.678277458590179, "XTANDI": 0.3457677072592053, "YESCARTA": 0.3451065054855847, "ZOSTAVAX": 0.2379520875192977, "ZYPREXA": 0.9733959487033684, "null": 1.1083719617111265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9750.json
new file mode 100644
index 00000000000..5adb9fbef98
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9750.json
@@ -0,0 +1 @@
+{"null": 1.7353989582426508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9751.json
new file mode 100644
index 00000000000..3461150bcc6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9751.json
@@ -0,0 +1 @@
+{"GREPID": 480.6615881764384, "null": 11.645303451367512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9752.json
new file mode 100644
index 00000000000..40d54fabe10
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9752.json
@@ -0,0 +1 @@
+{"FIASP": 1915.7086965212984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9753.json
new file mode 100644
index 00000000000..4c597e613d2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9753.json
@@ -0,0 +1 @@
+{"CHAMPIX": 26.225322480846494, "null": 3.9034699607941903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9754.json
new file mode 100644
index 00000000000..a8fdf812b4c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9754.json
@@ -0,0 +1 @@
+{"null": 2.4045011589818754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9755.json
new file mode 100644
index 00000000000..5009c84a84f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9755.json
@@ -0,0 +1 @@
+{"TREMFYA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9756.json
new file mode 100644
index 00000000000..ca5772d2e8f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9756.json
@@ -0,0 +1 @@
+{"ADALIMUMAB": 3.917469629525319, "ARAVA": 9.402919598981809, "null": 2.2958016649183035}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9757.json
new file mode 100644
index 00000000000..9f0c2bd692e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9757.json
@@ -0,0 +1 @@
+{"ELIQUIS": 3.4789706495927963, "HUMIRA": 8.403708208447815, "SIMPONI": 5.474097044557135, "STELARA": 6.494708204146062, "TREMFYA": 23.865591817840414, "null": 2.904525762329399}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9758.json
new file mode 100644
index 00000000000..e9e2997022c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9758.json
@@ -0,0 +1 @@
+{"null": 6.536921368334963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9759.json
new file mode 100644
index 00000000000..7252fd83303
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9759.json
@@ -0,0 +1 @@
+{"ACTRAPID": 7.336652671392606, "CIMZIA": 0.716393650500827, "FIASP": 30.90345513046058, "IBUPROFEN": 1.0869123237821767, "LEVEMIR": 7.7937799363659135, "NOVORAPID": 2060.135082327455, "SAXENDA": 1.7091002108728253, "SIMPONI": 4.408432270846336, "STELARA": 2.7086938895398203, "TREMFYA": 74.05848220682614, "TRESIBA": 28.015484939838466, "null": 0.2596274239906735}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/976.json
index 21894391266..21149424d17 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/976.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/976.json
@@ -1 +1 @@
-{"BIKTARVY": 128.9348046977465}
\ No newline at end of file
+{"null": 1.450559832481225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9760.json
new file mode 100644
index 00000000000..b94b39e8c62
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9760.json
@@ -0,0 +1 @@
+{"GARDASIL": 42.803307723476735, "null": 2.1948415985234866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9761.json
new file mode 100644
index 00000000000..87adaed479b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9761.json
@@ -0,0 +1 @@
+{"STELARA": 5.750538668778316, "null": 3.864900442931406}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9762.json
new file mode 100644
index 00000000000..97571db9910
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9762.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 6.706016385458204, "EMPAGLIFLOZIN": 67.54661012311233, "ENTRESTO": 11.71672629759177, "INSULIN": 25.687872330307226, "OLANZAPINE": 8.010129782590283, "SITAGLIPTIN": 290.8439585151044, "null": 2.264399766529977}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9763.json
new file mode 100644
index 00000000000..95b0549fbb6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9763.json
@@ -0,0 +1 @@
+{"GARDASIL": 7.150586329123432, "HUMALOG": 10.606036935188929, "null": 5.089315574042916}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9764.json
new file mode 100644
index 00000000000..946fa89e658
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9764.json
@@ -0,0 +1 @@
+{"APIDRA": 4.189979885259958, "CLOPIDOGREL": 0.986387907394484, "IBUPROFEN": 1.959589331557168, "LANTUS": 3.2669705433776577, "NOVORAPID": 19.28299296137272, "SAXENDA": 4.758113216793893, "null": 9.432212191113155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9765.json
new file mode 100644
index 00000000000..0806ae9907c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9765.json
@@ -0,0 +1 @@
+{"GARDASIL": 63.06277500021524, "null": 3.5795593138027377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9766.json
new file mode 100644
index 00000000000..381974a37cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9766.json
@@ -0,0 +1 @@
+{"null": 2.37689208818608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9767.json
new file mode 100644
index 00000000000..73e140652c3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9767.json
@@ -0,0 +1 @@
+{"BIKTARVY": 21.230167513596108, "null": 10.495414322009989}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9768.json
new file mode 100644
index 00000000000..3686ef3c9e5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9768.json
@@ -0,0 +1 @@
+{"null": 9.480802053331818}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9769.json
new file mode 100644
index 00000000000..e4f086c040e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9769.json
@@ -0,0 +1 @@
+{"BIKTARVY": 40.79061362810873, "IBRANCE": 16.420189330666723, "null": 3.039816286439364}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/977.json
index dc4beda7c41..bf436501836 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/977.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/977.json
@@ -1 +1 @@
-{"ENTECAVIR": 1119.2050576317483}
\ No newline at end of file
+{"COMIRNATY": 0.6580971611452429, "ELIQUIS": 1.6423997615130534, "TOZINAMERAN": 0.880272419390721, "VAXZEVRIA": 0.4317727553435559, "null": 1.3014378560719713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9770.json
new file mode 100644
index 00000000000..dc80610a23b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9770.json
@@ -0,0 +1 @@
+{"COSENTYX": 1.8574152545695009, "ELIQUIS": 1.0054609612482042, "EXFORGE": 5.314014646248573, "IBRANCE": 1.801215444545036, "SIMPONI": 5.038172966740743, "STELARA": 5.535449610677518, "null": 4.234822357915313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9771.json
new file mode 100644
index 00000000000..6c4033b6aa2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9771.json
@@ -0,0 +1 @@
+{"BYDUREON": 24.239774742713585, "ELIQUIS": 5.089219721641292, "JANUVIA": 7.323581151586458, "SIMPONI": 5.658606641082699, "STELARA": 3.2769697664943207, "null": 2.978224820255561}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9772.json
new file mode 100644
index 00000000000..4cd8be9503b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9772.json
@@ -0,0 +1 @@
+{"APIDRA": 7.49504118603207, "NEVANAC": 475.8685099859572, "null": 8.671151343335088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9773.json
new file mode 100644
index 00000000000..59b518138ba
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9773.json
@@ -0,0 +1 @@
+{"ACTRAPID": 7.995969630384268, "APIDRA": 1.5697080740397171, "BRAFTOVI": 6.193438917247973, "COLOBREATHE": 173.9784084673403, "ELIQUIS": 0.3255101485834258, "ENTRESTO": 1.406136164279754, "FIASP": 58.55406250142136, "GALAFOLD": 22.632470588815448, "HUMALOG": 0.7163910700438585, "IBRANCE": 0.633950625804505, "IBUPROFEN": 1.0585920032154252, "JANUMET": 1.5518363143274625, "LEVEMIR": 10.354442810189456, "MICARDIS": 2.74932061350575, "NINLARO": 17.10124564727359, "NOVORAPID": 278.3976139497674, "STELARA": 0.8750105624025359, "TRESIBA": 37.11796127080368, "VELTASSA": 7.1747585753016505, "XTANDI": 2.810342116830472, "null": 2.4543500253353754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9774.json
new file mode 100644
index 00000000000..b00578bfbf5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9774.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1164211097314845, "LANTUS": 1.2405988603910425, "NOVORAPID": 8.548006383130557, "TOZINAMERAN": 1.7569876779485825, "VELTASSA": 22.44627072962048, "null": 2.2019085524622164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9775.json
new file mode 100644
index 00000000000..4b0ed649289
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9775.json
@@ -0,0 +1 @@
+{"BUPRENORPHINE": 52.070351000802425, "BYDUREON": 1.4903530277971764, "COMIRNATY": 0.0634875608269133, "HUMALOG": 0.4535495868632624, "KEPPRA": 0.5002914634093427, "LANTUS": 0.3827811206081375, "MENVEO": 8.599709621853313, "OPIOIDS": 72.06738655976147, "SHINGRIX": 1.2225490375031505, "SOLIRIS": 1.6152227372847592, "SUBOXONE": 321.29017703116045, "TOZINAMERAN": 0.178780464505763, "null": 1.300240612192634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9776.json
new file mode 100644
index 00000000000..27a5110edc1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9776.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.5445767632939855, "AERIUS": 3.122396510697026, "AMIKACIN": 4.222294779045326, "APIDRA": 2.7534555921799218, "APIXABAN": 1.7468177416449715, "ARAVA": 0.0509976977469266, "ARIPIPRAZOLE": 3.5906746110044043, "BENLYSTA": 0.9683153447011718, "BOSULIF": 1.9481249631933275, "BRAFTOVI": 4.166942773383198, "BRILIQUE": 1.368710330987581, "BUDESONIDE": 0.3862115546049589, "BUPRENORPHINE": 1.0321906901594524, "BYETTA": 0.5299972901095802, "CANAGLIFLOZIN": 29.981951327051757, "CHAMPIX": 0.8192844104452089, "CICLOSPORIN": 0.336728913305837, "CIMZIA": 0.5210700856923, "CLOPIDOGREL": 1.374409765980953, "COSENTYX": 5.046783442591714, "CYMBALTA": 0.3757229095437838, "DESLORATADINE": 6.887527920789664, "ELIQUIS": 2.322468112323638, "EMPAGLIFLOZIN": 3.152934165131456, "ENTRESTO": 7.364862618951516, "ENTYVIO": 0.603690324367416, "EXFORGE": 4.134033899364286, "FASLODEX": 1.1321085286545067, "FENTANYL": 2.186768366559894, "FORSTEO": 0.4339980118304439, "HUMALOG": 1.711622930535975, "IBRANCE": 2.093324538622906, "IBUPROFEN": 1.7127498185506709, "INLYTA": 1.6713968354041766, "INSULIN": 1.470218150112683, "ISENTRESS": 1.963473898739032, "JANUMET": 1.478489460557974, "JANUVIA": 1.5982085366290537, "JARDIANCE": 0.8309875871896255, "KEPPRA": 2.0288768251325697, "KEYTRUDA": 0.1980910427641154, "LANTUS": 0.6953080726677013, "LEVETIRACETAM": 1.440110572523038, "LEVOFLOXACIN": 0.9821331223708004, "LIXIANA": 5.28942153508757, "LONSURF": 2.4059803976167813, "LYNPARZA": 1.582580849983137, "LYRICA": 0.9972973894040552, "MELATONIN": 4.5332720838836975, "NOVOMIX": 30.03727917918204, "NOVORAPID": 0.8406257558963012, "NOXAFIL": 9.248677374246196, "OCALIVA": 15.9354432815253, "OLANZAPINE": 1.3833245971593044, "OMALIZUMAB": 0.6255988337739365, "OPTIMARK": 2.0259540127447817, "PEGINTRON": 0.4746386085306299, "PLAVIX": 0.7535132836548484, "PREGABALIN": 5.00545959151239, "RAPAMUNE": 10.12193381331981, "REVATIO": 2.268025085308202, "RUBRACA": 1.7671227803634262, "SIMPONI": 1.7127608843266884, "SOMATROPIN": 10.437622371213305, "SPIRONOLACTONE": 2.581164084378152, "STALEVO": 4.978415313901908, "STELARA": 1.4010129774284523, "SUBOXONE": 2.2503529369889703, "SUTENT": 0.53427567698743, "TAMIFLU": 0.991685901290734, "TOVIAZ": 6.357167940172565, "TRELEGY": 1.4738713451506755, "TRULICITY": 0.7263710360987827, "VFEND": 1.9722561080090104, "VIAGRA": 1.2133217793708413, "VICTOZA": 1.09923774227071, "XELJANZ": 3.911230820200182, "XTANDI": 0.3982460089789186, "ZYPREXA": 0.2520410543443379, "null": 2.8290954794200296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9777.json
new file mode 100644
index 00000000000..27e982df533
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9777.json
@@ -0,0 +1 @@
+{"AERIUS": 15.159125114701895, "ANORO": 6.289135674421059, "APIDRA": 1.9412450461079345, "AVAMYS": 10.76332889988464, "BUDESONIDE": 0.8789631169451192, "BUPRENORPHINE": 4.784237068293692, "CABOMETYX": 4.450954687311735, "CIMZIA": 0.9904754131702386, "CLOPIDOGREL": 11.732822170999883, "DEXAMETHASONE": 0.930328911041774, "ELIQUIS": 0.3176140658335625, "ENOXAPARIN": 5.360744623602257, "ENTRESTO": 1.207660675578471, "EYLEA": 3.4863876344525475, "FENTANYL": 1.1730241922253852, "IBRANCE": 2.313810353131592, "INSULIN": 1.9294919943740076, "JANUMET": 5.861094022116866, "JANUVIA": 2.526348914057953, "JARDIANCE": 0.7193008751648378, "KEYTRUDA": 0.9318069098497898, "LANTUS": 2.644605056816834, "OLANZAPINE": 1.357830296510317, "PLAVIX": 1.3858292387886173, "RELVAR": 15.576082414777268, "SUBOXONE": 0.978638914221826, "SUTENT": 0.2692225403474418, "TICAGRELOR": 28.85639652403592, "TOUJEO": 4.653400593218763, "TRELEGY": 9.137041115051078, "XARELTO": 5.062092678220416, "XELJANZ": 4.481145876880671, "null": 2.754302710009158}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9778.json
new file mode 100644
index 00000000000..c1492f675a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9778.json
@@ -0,0 +1 @@
+{"null": 8.707481839845515}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9779.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9779.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/978.json
index 3f18c86852a..3f684359e79 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/978.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/978.json
@@ -1 +1 @@
-{"ABACAVIR": 25.67870412641772, "ATAZANAVIR": 28.761612174353623, "ATRIPLA": 1.7817057498616211, "BIKTARVY": 172.74621696273675, "CABOTEGRAVIR": 190.97613193718212, "CELSENTRI": 84.61754071722183, "CYTARABINE": 17.218419021522823, "DARUNAVIR": 112.31137603770236, "DESCOVY": 152.8702349110133, "DOLUTEGRAVIR": 161.48362298599707, "EFAVIRENZ": 44.96172026973085, "EMTRICITABINE": 77.30947989876877, "EPIVIR": 28.836376872901727, "GENVOYA": 247.8087451022996, "ISENTRESS": 39.31373695329639, "KALETRA": 24.328441077293157, "LAMIVUDINE": 44.768193447434825, "REKAMBYS": 271.67295980081406, "STRIBILD": 8.017341240353831, "SYMTUZA": 181.838687104936, "TIVICAY": 113.2947565518387, "TRIUMEQ": 94.5397674005564, "TRUVADA": 5.4504545664058295}
\ No newline at end of file
+{"ENTRESTO": 20.15894567754527, "MEXILETINE": 2550.613125453545, "null": 1.3579990609454584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9780.json
new file mode 100644
index 00000000000..9fbbc8f4b40
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9780.json
@@ -0,0 +1 @@
+{"null": 1.7094405736763596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9781.json
new file mode 100644
index 00000000000..44831143d9a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9781.json
@@ -0,0 +1 @@
+{"ABATACEPT": 0.9768917344054168, "ACTRAPID": 10.088048977106665, "ADALIMUMAB": 1.3785767003296223, "AIMOVIG": 1.398611274835641, "APIDRA": 7.320646914415533, "APREMILAST": 10.715493763558364, "ARANESP": 0.4949441120327041, "BARACLUDE": 2.1234511509134344, "BRIDION": 2.442112222627777, "BRIVIACT": 1.6444932516238022, "BUPRENORPHINE": 2.2108090515708283, "BYDUREON": 10.2477562310189, "BYETTA": 4.809079677645833, "CIMZIA": 1.987315428088525, "CLOPIDOGREL": 0.1742091575858017, "COAPROVEL": 1.0395624144032902, "COMIRNATY": 0.0035071534349176, "COSENTYX": 0.7357581256997779, "DUORESP": 24.11862619415123, "ELIQUIS": 0.2816959270202418, "EVENITY": 1.1709289280002255, "EVRA": 2.288637478112077, "EXFORGE": 0.6933068148901219, "EYLEA": 0.8923719249324268, "FIASP": 29.729915004614316, "GARDASIL": 0.2472919208057363, "HUMALOG": 0.3263708009224145, "IBUPROFEN": 0.30947167675973, "INSULATARD": 16.843550912533086, "INSULIN": 0.9723017221833338, "INSUMAN": 8.006479920118634, "JANUMET": 1.7948383286376477, "JANUVIA": 0.7517466511825858, "JARDIANCE": 0.9164128319251929, "KEPPRA": 1.7343545802321594, "LANTUS": 3.993131680677228, "LEVEMIR": 10.177586123153798, "LEVETIRACETAM": 0.362855339154758, "MICARDIS": 2.768994884163483, "MIXTARD": 7.925849101663631, "MMRVAXPRO": 1.5043877747870067, "NEVANAC": 34.439167940621, "NOVORAPID": 43.941061065418765, "NOXAFIL": 2.685614224675173, "OLYSIO": 13.823559289434725, "OMNITROPE": 10.19779197379122, "PANTOPRAZOLE": 0.6155369715780242, "PEGASYS": 0.4814583834884035, "PEGINTRON": 3.8121735086498303, "PLAVIX": 0.3871792786908698, "PRIVIGEN": 1.0469067694165874, "QUTENZA": 4.776658249530487, "ROACTEMRA": 0.3805923797975824, "SAXENDA": 5.8477870037826944, "SIFROL": 1.7373260513658442, "SIMPONI": 3.682070974331589, "STALEVO": 2.3635455221260697, "STELARA": 0.5906722762614494, "TAMIFLU": 0.5907419095865322, "TESTOSTERONE": 13.846996295569904, "TOUJEO": 10.657454019343618, "TREMFYA": 9.743152159918235, "TRESIBA": 21.20363348604465, "VIAGRA": 0.5281387346718854, "VICTOZA": 3.0729076703986844, "VIMPAT": 0.7332521290765754, "XOLAIR": 1.041112981478513, "XTANDI": 0.2654583207364254, "ZONISAMIDE": 7.581383850589211, "ZOSTAVAX": 0.3102211120491951, "null": 3.5536364657971777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9782.json
new file mode 100644
index 00000000000..24df727e5ab
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9782.json
@@ -0,0 +1 @@
+{"null": 3.203894389960938}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9783.json
new file mode 100644
index 00000000000..4de88e39502
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9783.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.4371265063201817, "BRILIQUE": 5.0211779703557085, "CLOPIDOGREL": 0.8673662503083636, "EXFORGE": 2.287583403744086, "FAMPYRA": 9.357732284769003, "JANUMET": 1.8547602841815511, "JANUVIA": 2.167479693854709, "KEPPRA": 1.4526404283122027, "LEVETIRACETAM": 2.533058174618461, "LIXIANA": 12.95337182245376, "PLAVIX": 1.1163467419225073, "RANOLAZINE": 16.90370673062155, "RINVOQ": 49.28854878727334, "SIFROL": 8.836813178268656, "STALEVO": 10.629254931708047, "TRELEGY": 2.624912776711418, "UPADACITINIB": 62.28564945344207, "VIRAMUNE": 44.68375910299325, "XELJANZ": 0.5675618845879796, "null": 5.7310323767975575}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9784.json
new file mode 100644
index 00000000000..340089c4d92
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9784.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9785.json
new file mode 100644
index 00000000000..024b4046088
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9785.json
@@ -0,0 +1 @@
+{"null": 4.41353939513179}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9786.json
new file mode 100644
index 00000000000..db4ebc97885
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9786.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9787.json
new file mode 100644
index 00000000000..53e29d42078
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9787.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9788.json
new file mode 100644
index 00000000000..507a73f3b26
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9788.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9789.json
new file mode 100644
index 00000000000..23cb0e0e45b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9789.json
@@ -0,0 +1 @@
+{"null": 2.805853187951373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/979.json
index abd9c33c0b4..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/979.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/979.json
@@ -1 +1 @@
-{"null": 2.158702033383775}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9790.json
new file mode 100644
index 00000000000..87b490a5593
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9790.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9791.json
new file mode 100644
index 00000000000..29f9b406332
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9791.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9792.json
new file mode 100644
index 00000000000..e3721e86685
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9792.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9793.json
new file mode 100644
index 00000000000..588971cdbde
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9793.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9794.json
new file mode 100644
index 00000000000..84e572f30f1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9794.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9795.json
new file mode 100644
index 00000000000..4852a65a30b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9795.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9796.json
new file mode 100644
index 00000000000..b9d3c2c5129
--- /dev/null
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@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9797.json
new file mode 100644
index 00000000000..b8b84e2c54d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9797.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9798.json
new file mode 100644
index 00000000000..f98727b5f2a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9798.json
@@ -0,0 +1 @@
+{"null": 0.6150315419721749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9799.json
new file mode 100644
index 00000000000..8bdddd041dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9799.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/98.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/98.json
index 58837d6ed0a..aaafc70d7e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/98.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/98.json
@@ -1 +1 @@
-{"HEPSERA": 2329.632271930392}
\ No newline at end of file
+{"SUGAMMADEX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/980.json
index 50333e1a8c1..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/980.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/980.json
@@ -1 +1 @@
-{"AFINITOR": 3.462448718389714, "AMIKACIN": 6.092170882102, "AMINOSALICYLIC": 12.896221370899845, "ARIPIPRAZOLE": 8.767597480990874, "ASPARAGINASE": 3.48755324015512, "BEDAQUILINE": 20.64720499396428, "BEVACIZUMAB": 4.0883085805486585, "BYETTA": 1.3014951018803051, "CABOMETYX": 3.550104651418957, "CAPECITABINE": 3.430520576154891, "CICLOSPORIN": 2.307473057066554, "CLOPIDOGREL": 2.1995736055801647, "COSENTYX": 2.1558152199800573, "DELAMANID": 23.40173086900297, "DEXAMETHASONE": 1.2367547821770466, "EMEND": 11.072762026873674, "ENTYVIO": 1.309627255847995, "EXFORGE": 2.9870501055939824, "EXJADE": 10.034358852646903, "FENTANYL": 2.2674013621058693, "HUMIRA": 1.671522026970959, "IBRANCE": 1.3127521743853283, "INLYTA": 1.8199164910213417, "KEYTRUDA": 2.271197452634864, "KYMRIAH": 7.287499776215023, "LENVIMA": 10.562859355633238, "LYRICA": 1.5446536453458637, "MEKINIST": 2.0701002513827924, "NALOXONE": 64.424764673388, "NEXAVAR": 6.378044209935301, "OCALIVA": 17.153475142848897, "OLANZAPINE": 1.3521781837673028, "OLYSIO": 9.268549993358006, "OMALIZUMAB": 1.8483922570659967, "OPSUMIT": 1.1382526907061894, "PEGASYS": 2.340341314977856, "PEGINTRON": 1.6096739600151655, "SOLIRIS": 3.505038087470169, "STIVARGA": 4.575094701203058, "SUTENT": 2.6280549115164717, "TRACLEER": 1.5170898363714662, "VFEND": 4.080946502366965, "VOTRIENT": 2.402585991408558, "XALKORI": 6.441289094879018}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9800.json
new file mode 100644
index 00000000000..d37e39ee87a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9800.json
@@ -0,0 +1 @@
+{"BOTULINUM": 90.75811343070016, "TRELEGY": 24.470497851304785, "null": 1.8306723688539732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9801.json
new file mode 100644
index 00000000000..3ecc8320114
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9801.json
@@ -0,0 +1 @@
+{"null": 13.819884609979711}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9802.json
new file mode 100644
index 00000000000..3e0c6e344f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9802.json
@@ -0,0 +1 @@
+{"ACLIDINIUM": 12.673877489259858, "ADEMPAS": 2.4414356644276016, "AERIUS": 2.154455305948161, "AFINITOR": 2.580357679967095, "AIMOVIG": 0.1598114032995312, "ALEMTUZUMAB": 0.8944760098911866, "ALENDRONATE": 35.30089351652676, "ALIMTA": 0.6343532337942447, "AMBRISENTAN": 10.476618575923926, "AMIKACIN": 1.1639003422452336, "ANORO": 30.195563057228767, "APIXABAN": 6.834614283181529, "ARAVA": 0.1881360309517321, "ASPARAGINASE": 0.6763799716039357, "ATEZOLIZUMAB": 4.638383271499942, "AUBAGIO": 0.2677399352988047, "AVAMYS": 7.769253792058092, "AVASTIN": 0.400608848097072, "AZATHIOPRINE": 4.018673900398082, "BEDAQUILINE": 2.214394937605768, "BENLYSTA": 3.219902346718569, "BENRALIZUMAB": 8.13468241454297, "BEVACIZUMAB": 0.4334939046311457, "BIKTARVY": 0.7405522577045326, "BUDESONIDE": 3.074658513988348, "BUPRENORPHINE": 0.5083996450601493, "BUSULFAN": 0.5900075891240077, "CABOMETYX": 0.6925066652327422, "CANAGLIFLOZIN": 7.383344745186011, "CANCIDAS": 1.1971977208332256, "CELLCEPT": 0.9427041135406729, "CHAMPIX": 0.3414128702802018, "CICLOSPORIN": 1.169761471038274, "CIMZIA": 0.4999330717397124, "CLOPIDOGREL": 1.0077316617375671, "COMBIVIR": 0.6545662782130872, "COMIRNATY": 0.4498596898793509, "COSENTYX": 2.027236463500937, "CYMBALTA": 0.3193223049580625, "CYTARABINE": 0.4069862585304542, "DARZALEX": 1.065286908297113, "DESLORATADINE": 7.694851592706317, "DEXAMETHASONE": 0.6617014622607871, "DOCETAXEL": 0.4999211956455417, "DOXORUBICIN": 1.4571872078419523, "DUAKLIR": 28.69742741506821, "DULOXETINE": 1.1623644309115266, "DUPIXENT": 4.169174404013628, "ELIQUIS": 0.4273667935223003, "ENBREL": 0.3330336291614089, "ENTRESTO": 1.1701411138573632, "ENTYVIO": 0.746928165701287, "ENVARSUS": 20.920691495028183, "ERELZI": 4.261134224285573, "ESBRIET": 6.2520471776498034, "EXFORGE": 0.730969378373876, "EXJADE": 0.7533269884072076, "FASENRA": 4.276472459381777, "FILGRASTIM": 2.0603241596788977, "FLUTICASONE": 22.63996277750792, "FORSTEO": 0.1992616190567996, "FULVESTRANT": 0.7840913192261129, "GARDASIL": 0.1783026868817589, "GLYCOPYRRONIUM": 35.22558742791208, "HIZENTRA": 2.8400340721295656, "HUMALOG": 0.1612013720330843, "HUMIRA": 0.5096996852773562, "IBRANCE": 1.328920943876244, "IBUPROFEN": 1.0415498390392182, "INCRUSE": 8.02698776465279, "INFLIXIMAB": 1.2958702984257309, "INLYTA": 1.1724729672280183, "INSULIN": 5.005788636307933, "INVOKANA": 1.7336998747124075, "IRBESARTAN": 0.7314226639296997, "IRESSA": 0.5985674768552507, "JAKAVI": 0.2940997227226365, "JANUVIA": 0.2037333941760102, "JARDIANCE": 0.1623795342383892, "JEVTANA": 0.9892954409932668, "KAFTRIO": 15.524968046897744, "KALETRA": 0.7724540307743657, "KALYDECO": 4.167342664848204, "KEYTRUDA": 0.6715780975711215, "KISQALI": 0.737679844915986, "LANTUS": 0.0924907557028911, "LEMTRADA": 0.630546136616736, "LEVETIRACETAM": 0.3402746173909278, "LEVOFLOXACIN": 0.9413566708966484, "LYRICA": 0.8735369916871532, "MANNITOL": 6.105726415386842, "MEKINIST": 0.3120699814600203, "MEPOLIZUMAB": 20.38724213177979, "METHOTREXATE": 3.425658042381957, "MICARDIS": 0.558846178182438, "MIDAZOLAM": 0.6567264937685243, "MMRVAXPRO": 0.4275356470684063, "MODERNA": 0.336760086985664, "MULTAQ": 0.8971788466106319, "MYCOPHENOLATE": 1.3326113614013102, "NAGLAZYME": 5.686594710825485, "NEULASTA": 0.6555803870128869, "NEXAVAR": 0.3853754954455712, "NUCALA": 20.492191318625213, "OCRELIZUMAB": 0.5132811215371184, "OFEV": 7.921496209644519, "OMALIZUMAB": 14.519553369405612, "OPSUMIT": 3.195605543788275, "ORKAMBI": 6.474440952637258, "PANTOPRAZOLE": 4.824757522846892, "PEGASYS": 1.2829420693175693, "PEGINTRON": 0.9798771817373269, "PLAVIX": 0.2983233586803124, "PREGABALIN": 2.976907677100928, "PRIVIGEN": 0.4798591161472627, "RELVAR": 11.245277341145908, "REVATIO": 1.6648104951483644, "RINVOQ": 0.6324532307747527, "RITUXIMAB": 2.3178581930874107, "RIVAROXABAN": 3.4527465462444105, "ROTATEQ": 0.5568842559286552, "SILDENAFIL": 1.1648904396656408, "SIMPONI": 0.9584281248034646, "SOLIRIS": 0.671278730033332, "SPIKEVAX": 0.4790015410987514, "SPINRAZA": 0.92877398144393, "SPIRONOLACTONE": 1.1852610517168225, "SPRYCEL": 0.8250852122002964, "STELARA": 0.4550363380475491, "STIVARGA": 0.5655632004041288, "SUTENT": 0.8543081569773222, "SYNAGIS": 1.4824413796954268, "TAGRISSO": 0.6561676559557262, "TAMIFLU": 0.295340734296323, "TASIGNA": 0.7282853362498076, "TOBRAMYCIN": 2.4334306499190306, "TOZINAMERAN": 0.809501774265686, "TRACLEER": 1.2653858008627206, "TRELEGY": 12.120633956747284, "UMECLIDINIUM": 18.850293342668937, "VALSARTAN": 1.5939195497592225, "VARENICLINE": 14.740983499543688, "VAXZEVRIA": 0.2844230480761512, "VFEND": 0.5246075464228347, "VIAGRA": 0.334476319015746, "VOTRIENT": 0.6967238137959498, "XALKORI": 0.9724819348253672, "XARELTO": 0.9213358214063756, "XELJANZ": 1.7045484759407177, "XOLAIR": 7.555071575066395, "XTANDI": 0.9850404002692916, "ZOSTAVAX": 0.5691133652654576, "null": 0.857602598428548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9803.json
new file mode 100644
index 00000000000..28c9315c5fb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9803.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9804.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9804.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9805.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9805.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9806.json
new file mode 100644
index 00000000000..45199298fde
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9806.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.5916170441023603, "null": 2.240902606472871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9807.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9807.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9808.json
new file mode 100644
index 00000000000..30de5feaee0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9808.json
@@ -0,0 +1 @@
+{"null": 4.191237802781421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9809.json
new file mode 100644
index 00000000000..3f6342260db
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9809.json
@@ -0,0 +1 @@
+{"null": 3.790928319436961}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/981.json
index d3f174671c2..8dc465266d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/981.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/981.json
@@ -1 +1 @@
-{"null": 1.104329565437147}
\ No newline at end of file
+{"null": 1.2792279924443763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9810.json
new file mode 100644
index 00000000000..1fa62ca5f61
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9810.json
@@ -0,0 +1 @@
+{"EVENITY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9811.json
new file mode 100644
index 00000000000..ef55dae20d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9811.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 24.888469872035817, "null": 4.6333208081956485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9812.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9812.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9813.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9813.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9814.json
new file mode 100644
index 00000000000..b70ce22d08a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9814.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1506.060606607389, "CRIXIVAN": 317.3889860292967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9815.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9815.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9816.json
new file mode 100644
index 00000000000..4f6b49118a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9816.json
@@ -0,0 +1 @@
+{"TOZINAMERAN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9817.json
new file mode 100644
index 00000000000..709acdfccc2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9817.json
@@ -0,0 +1 @@
+{"ABACAVIR": 4.986634574696754, "ALEMTUZUMAB": 57.62342903644289, "ATAZANAVIR": 11.75741901625023, "AZACITIDINE": 16.383356634562368, "AZATHIOPRINE": 3.870765195545935, "BENLYSTA": 8.222367582116624, "BIKTARVY": 4.782743068794248, "BORTEZOMIB": 33.05804275521204, "BUSULFAN": 16.862695294286763, "CAELYX": 11.182075505572945, "CARFILZOMIB": 77.84407383075437, "CARMUSTINE": 35.32857658513915, "CELLCEPT": 32.27556492183811, "CICLOSPORIN": 4.258428004221803, "CIDOFOVIR": 88.93765803221706, "CYTARABINE": 5.10487787093283, "DEXAMETHASONE": 6.663279839110018, "DOLUTEGRAVIR": 31.865709654787818, "DOXORUBICIN": 12.903090360990753, "EFAVIRENZ": 14.39666948916742, "ENTYVIO": 4.65256022130237, "EPIVIR": 17.022703380064378, "FAMPYRA": 6.026203641548, "FILGRASTIM": 15.817642690554772, "GAZYVARO": 61.29121853312946, "IBRUTINIB": 38.77745130906629, "INDINAVIR": 79.22306257314399, "JAKAVI": 4.522983552804912, "KALETRA": 11.558035105725624, "LAMIVUDINE": 14.334710120202152, "LEMTRADA": 6.964882080595932, "MABCAMPATH": 67.38752508970668, "MABTHERA": 89.70245689681086, "METHOTREXATE": 3.484820444395952, "MYCOPHENOLATE": 7.6479679881112705, "OBINUTUZUMAB": 24.636375546315737, "PEGASYS": 0.6356239307969354, "RITUXIMAB": 19.655282681471512, "TIVICAY": 20.686411956313982, "TYSABRI": 113.94990060839072, "null": 0.209216721002341}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9818.json
new file mode 100644
index 00000000000..4e9a04dd33a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9818.json
@@ -0,0 +1 @@
+{"ARIPIPRAZOLE": 62.86811533630221, "AUBAGIO": 96.6633403339054, "FAMPYRA": 152.63946659739963, "null": 0.1774913059248756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9819.json
new file mode 100644
index 00000000000..03ccfcddb25
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9819.json
@@ -0,0 +1 @@
+{"OLANZAPINE": 41.071245764346, "null": 0.6962929566312785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/982.json
index 1aac1c254bf..899c92dc9ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/982.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/982.json
@@ -1 +1 @@
-{"null": 1.2243969595857331}
\ No newline at end of file
+{"STALEVO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9820.json
new file mode 100644
index 00000000000..b88596f58fc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9820.json
@@ -0,0 +1 @@
+{"null": 4.975846767140154}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9821.json
new file mode 100644
index 00000000000..03c0b268607
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9821.json
@@ -0,0 +1 @@
+{"null": 0.3172598689030601}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9822.json
new file mode 100644
index 00000000000..7e2a2380eff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9822.json
@@ -0,0 +1 @@
+{"INSULIN": 289.61684802116247, "MEPOLIZUMAB": 64.67397885533937, "NUCALA": 34.61917093894282, "TELMISARTAN": 84.50497864567333, "null": 0.5386714334346587}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9823.json
new file mode 100644
index 00000000000..b0599365af8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9823.json
@@ -0,0 +1 @@
+{"null": 1.9564605172969511}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9824.json
new file mode 100644
index 00000000000..bcf3f798f70
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9824.json
@@ -0,0 +1 @@
+{"null": 0.8543727500275625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9825.json
new file mode 100644
index 00000000000..71e9bbf3446
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9825.json
@@ -0,0 +1 @@
+{"null": 2.278058895532269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9826.json
new file mode 100644
index 00000000000..e85e6b5195c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9826.json
@@ -0,0 +1 @@
+{"null": 9.945536853575687}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9827.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9827.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9828.json
new file mode 100644
index 00000000000..f59c453dd0b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9828.json
@@ -0,0 +1 @@
+{"BUDESONIDE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9829.json
new file mode 100644
index 00000000000..8b5194a1f61
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9829.json
@@ -0,0 +1 @@
+{"LEMTRADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/983.json
index 906f6807a4b..3ea60804996 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/983.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/983.json
@@ -1 +1 @@
-{"CHAMPIX": 6.960079101487062, "null": 3.5145677090731966}
\ No newline at end of file
+{"AMINOSALICYLIC": 7.441972642488024, "AVANDIA": 7.327198674532172, "CICLOSPORIN": 7.336698763060296, "COMIRNATY": 0.1280853368607412, "ELIQUIS": 2.2081799097784085, "HUMALOG": 2.5889196502540712, "JANUMET": 17.33624059352026, "PLAVIX": 2.180803799566201, "SUTENT": 1.2945672808684494, "TASIGNA": 42.11721586106293, "null": 0.9414731620791376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9830.json
new file mode 100644
index 00000000000..aaaccbf1bdf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9830.json
@@ -0,0 +1 @@
+{"TRUVADA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9831.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9831.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9832.json
new file mode 100644
index 00000000000..b72bd658853
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9832.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": 7.08133336413608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9833.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9833.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9834.json
new file mode 100644
index 00000000000..e194343b6ce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9834.json
@@ -0,0 +1 @@
+{"DEXAMETHASONE": 10.373999522743064, "FENTANYL": 4.301164296130044, "LEVETIRACETAM": 12.247010364483812, "MIDAZOLAM": 15.998029516098596, "null": 12.977562581501603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9835.json
new file mode 100644
index 00000000000..36692cb9d78
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9835.json
@@ -0,0 +1 @@
+{"null": 4.140491715066219}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9836.json
new file mode 100644
index 00000000000..45185fe806d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9836.json
@@ -0,0 +1 @@
+{"null": 1.094861664719999}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9837.json
new file mode 100644
index 00000000000..4fc1905d4d9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9837.json
@@ -0,0 +1 @@
+{"APROVEL": 1.6965029035820691, "ARANESP": 0.5238370392571539, "ARAVA": 0.0481672865607821, "ATRIPLA": 0.1402113619878469, "AUBAGIO": 0.3097956876742039, "AVANDIA": 0.3306174295775468, "BUDESONIDE": 0.7385512676835804, "BYDUREON": 2.34567752223421, "BYETTA": 1.1239912466442772, "CABAZITAXEL": 27.86466191457334, "CELLCEPT": 0.4880754482948917, "CIALIS": 14.872241062500802, "CICLOSPORIN": 0.3200398523357337, "CIMZIA": 0.7300362236298298, "CLOPIDOGREL": 0.5932293526782539, "COMIRNATY": 0.0324645754521968, "COSENTYX": 1.8420207063866945, "CYMBALTA": 0.4701913583651454, "DENOSUMAB": 7.172807603969819, "DEXAMETHASONE": 0.348665469939024, "DOCETAXEL": 3.8956577990466297, "ELIQUIS": 1.6596175750658435, "ENTRESTO": 0.4345638891781684, "ENTYVIO": 1.4153347355419228, "ENZALUTAMIDE": 22.199702073126844, "ERLEADA": 30.266294219724717, "ESBRIET": 0.8562631058249869, "EXFORGE": 1.685060511964193, "FORSTEO": 0.3235482807976813, "HUMALOG": 1.5356207157910662, "HUMIRA": 0.7217459944109771, "IRBESARTAN": 1.3446774324817516, "JAKAVI": 0.8029525583831273, "JANUMET": 1.1017592002943566, "JANUVIA": 1.1403718410250665, "JARDIANCE": 0.5908078537063414, "JEVTANA": 8.027783234947151, "KEYTRUDA": 0.2010724312855592, "LANTUS": 1.5961943401628107, "LEUPRORELIN": 46.12833308098613, "LEVEMIR": 0.5709249546235052, "LYNPARZA": 1.4357742194572678, "MEPOLIZUMAB": 0.5834891513146363, "METFORMIN": 10.83510027665936, "METHOTREXATE": 2.984737242389063, "MICARDIS": 1.2044777365431918, "NEXAVAR": 0.2648869822697671, "NPLATE": 1.9175765243335487, "NUBEQA": 43.88348774865375, "NUCALA": 1.6955569730305788, "OFEV": 1.0268905312088872, "PEGASYS": 0.3574716002855944, "PLAVIX": 0.5614720615128567, "PLUVICTO": 33.937123438531856, "REVLIMID": 1.893325593084416, "RINVOQ": 0.8686285742400252, "RITUXIMAB": 0.4331719936167055, "ROACTEMRA": 1.1432752743750292, "SILODOSIN": 37.36992534930331, "SIMPONI": 2.063496154382072, "SKYRIZI": 4.400558744395312, "SOLIRIS": 0.3642083543801228, "SPIKEVAX": 0.0314150901288959, "SPRYCEL": 0.7834165471684941, "STELARA": 5.608163351947523, "SUBOXONE": 0.2895156858878853, "SUTENT": 0.3111370032290453, "TASIGNA": 0.979493665111236, "TESTOSTERONE": 6.6830260146961855, "TOVIAZ": 1.7009886836125767, "TOZINAMERAN": 0.0606612736011316, "TRELEGY": 2.6021955441225035, "TREMFYA": 5.8682796212515855, "TRULICITY": 0.4782557853438193, "VAXZEVRIA": 0.0142546998234647, "VIAGRA": 31.883337595859853, "VICTOZA": 1.0877605315021015, "XELJANZ": 1.261398761418681, "XOFIGO": 41.492892838745455, "XOLAIR": 1.8496606079045843, "XTANDI": 10.816870647420302, "ZOSTAVAX": 1.6221816205194293, "ZYTIGA": 19.69964984498989, "null": 3.1600767937691656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9838.json
new file mode 100644
index 00000000000..7b4e8793169
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9838.json
@@ -0,0 +1 @@
+{"ABIRATERONE": 758.3802573695656, "APALUTAMIDE": 383.29016688632737, "CABAZITAXEL": 937.555949351506, "DEXAMETHASONE": 3.4940345959025114, "DOCETAXEL": 32.33352066749576, "ELIQUIS": 1.192860736037307, "ENZALUTAMIDE": 102.09108999847425, "ERLEADA": 211.62250043889804, "JEVTANA": 20.39173520269268, "PLUVICTO": 206.69547058818415, "STELARA": 1.9646933979414232, "XOFIGO": 274.4932174182316, "XTANDI": 23.287040880013382, "null": 0.4991446304887864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9839.json
new file mode 100644
index 00000000000..cf5b1de4496
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9839.json
@@ -0,0 +1 @@
+{"VIAGRA": 21.43258406191056, "XTANDI": 16.770769596990146, "null": 0.5315602473049383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/984.json
index 414522eabfe..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/984.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/984.json
@@ -1 +1 @@
-{"CLOPIDOGREL": 54.23659967521549}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9840.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9840.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9841.json
new file mode 100644
index 00000000000..7d56f332b73
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9841.json
@@ -0,0 +1 @@
+{"null": 2.938696518106536}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9842.json
new file mode 100644
index 00000000000..112e289b5d9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9842.json
@@ -0,0 +1 @@
+{"null": 7.224155163960526}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9843.json
new file mode 100644
index 00000000000..397d308bb10
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9843.json
@@ -0,0 +1 @@
+{"null": 6.401891465944409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9844.json
new file mode 100644
index 00000000000..921c01fdd1a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9844.json
@@ -0,0 +1 @@
+{"XOFIGO": 669.4171959392986, "null": 1.3402834708076132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9845.json
new file mode 100644
index 00000000000..ad74792f2a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9845.json
@@ -0,0 +1 @@
+{"NUCALA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9846.json
new file mode 100644
index 00000000000..b30067de1a6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9846.json
@@ -0,0 +1 @@
+{"null": 1.5854742411385632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9847.json
new file mode 100644
index 00000000000..96dcaec65be
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9847.json
@@ -0,0 +1 @@
+{"null": 0.7892680425851123}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9848.json
new file mode 100644
index 00000000000..f94a6536a25
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9848.json
@@ -0,0 +1 @@
+{"null": 2.330817813343336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9849.json
new file mode 100644
index 00000000000..dc15296d7ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9849.json
@@ -0,0 +1 @@
+{"JARDIANCE": 47.39180771061071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/985.json
index 7c31fa74a51..d15d524327a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/985.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/985.json
@@ -1 +1 @@
-{"null": 2.771171487222005}
\ No newline at end of file
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9850.json
new file mode 100644
index 00000000000..089782912de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9850.json
@@ -0,0 +1 @@
+{"IBRUTINIB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9851.json
new file mode 100644
index 00000000000..a107f8858a1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9851.json
@@ -0,0 +1 @@
+{"null": 1.154974243957014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9852.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9852.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9853.json
new file mode 100644
index 00000000000..492865b0db9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9853.json
@@ -0,0 +1 @@
+{"BYETTA": 72.36487152243265, "null": 0.5138213095224082}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9854.json
new file mode 100644
index 00000000000..4263211c200
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9854.json
@@ -0,0 +1 @@
+{"CLOPIDOGREL": 1.3530962273799407, "ELIQUIS": 8.278383868514549, "HUMALOG": 2.230417900787471, "LANTUS": 1.5403568958319875, "MEPOLIZUMAB": 5.516557624495455, "PLAVIX": 1.5179206494063062, "SPIKEVAX": 0.1046627472051159, "SUTENT": 1.4208019564268743, "TOVIAZ": 9.568910677146164, "VIAGRA": 67.30083479918393, "XELJANZ": 1.0979166977019648, "ZOSTAVAX": 7.405279193527647, "null": 2.123905293126544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9855.json
new file mode 100644
index 00000000000..fa2a5cec173
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9855.json
@@ -0,0 +1 @@
+{"XOFIGO": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9856.json
new file mode 100644
index 00000000000..839f02f08f9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9856.json
@@ -0,0 +1 @@
+{"ELIQUIS": 22.273692268031635, "null": 0.8928624848571264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9857.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9857.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9858.json
new file mode 100644
index 00000000000..7b3aa3a9d26
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9858.json
@@ -0,0 +1 @@
+{"null": 1.4308638089904002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9859.json
new file mode 100644
index 00000000000..65ec58bd2ff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9859.json
@@ -0,0 +1 @@
+{"ELIQUIS": 7.15959979716541, "LANTUS": 6.061922734849496, "null": 1.467814247157657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/986.json
index 7fecd8a8f94..371fd54ec0a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/986.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/986.json
@@ -1 +1 @@
-{"AVAMYS": 101.26146417182616, "KEYTRUDA": 5.584455930761068, "OCALIVA": 653.362880489703}
\ No newline at end of file
+{"CLOPIDOGREL": 20.585918367026107, "ELIQUIS": 10.04473188956085, "EMPAGLIFLOZIN": 41.14437771362002, "ENOXAPARIN": 38.33578699701604, "ENTRESTO": 5.577796016698047, "LENVIMA": 34.065267325009586, "PLAVIX": 6.354918828203465, "null": 1.3701490976631177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9860.json
new file mode 100644
index 00000000000..20615341083
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9860.json
@@ -0,0 +1 @@
+{"null": 2.5651016405039786}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9861.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9861.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9862.json
new file mode 100644
index 00000000000..d9d7fb53c5e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9862.json
@@ -0,0 +1 @@
+{"MEPOLIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9863.json
new file mode 100644
index 00000000000..8c7c569d024
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9863.json
@@ -0,0 +1 @@
+{"ADENURIC": 133.22310372597795, "ENZALUTAMIDE": 192.02129775730407, "XTANDI": 105.7858051350146, "null": 0.341717803760138}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9864.json
new file mode 100644
index 00000000000..90ede2837eb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9864.json
@@ -0,0 +1 @@
+{"null": 1.0552223260526887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9865.json
new file mode 100644
index 00000000000..8d85c3c89a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9865.json
@@ -0,0 +1 @@
+{"APALUTAMIDE": 97.51335005611386, "CABAZITAXEL": 170.35355658906403, "COMIRNATY": 0.0463104930824814, "COSENTYX": 0.8041349672139662, "DENOSUMAB": 13.005275668098822, "DEXAMETHASONE": 1.037745140511412, "DOCETAXEL": 15.147151532881155, "ELIQUIS": 0.8901292171580314, "ENZALUTAMIDE": 217.0682892284273, "ERLEADA": 83.62774384057815, "EXFORGE": 1.2611239350264047, "FORXIGA": 1.1902878891006237, "JARDIANCE": 0.5335185746804991, "JEVTANA": 73.54458657594722, "KEYTRUDA": 0.3703583245910892, "LEUPRORELIN": 233.6534224817427, "LYNPARZA": 12.805102644598067, "NUBEQA": 166.0449101665958, "OLAPARIB": 9.570237534789136, "PLUVICTO": 100.62671114972268, "STELARA": 0.7170761287463489, "SUTENT": 0.3768706885274194, "TAXOTERE": 8.12737713949123, "TESTOSTERONE": 9.965604403503, "VAXZEVRIA": 0.0319715612018773, "VIAGRA": 2.881588671329942, "XGEVA": 76.98881335539022, "XOFIGO": 245.9450899602774, "XOLAIR": 0.5046878849518996, "XTANDI": 236.49024028387117, "ZOSTAVAX": 0.9346362973974234, "null": 0.4255664965133819}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9866.json
new file mode 100644
index 00000000000..4c490ad03aa
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9866.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9867.json
new file mode 100644
index 00000000000..90ea7b6a2d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9867.json
@@ -0,0 +1 @@
+{"null": 2.03982116708144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9868.json
new file mode 100644
index 00000000000..a6f95eefd5c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9868.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.3143244495070608, "COSENTYX": 1.7553057989658576, "ELIQUIS": 1.1794514088752035, "FORXIGA": 35.04961403803839, "JANUMET": 5.078226143822495, "JARDIANCE": 24.707399880674732, "LEVOFLOXACIN": 2.60189522449981, "PEGASYS": 1.378534929716582, "SIMPONI": 1.966341185720376, "SPIKEVAX": 0.371858943722945, "TOZINAMERAN": 0.3609714582027638, "VAXZEVRIA": 0.1566134791302719, "ZOSTAVAX": 2.2363903833918157, "null": 1.1011655107927651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9869.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9869.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/987.json
index 47adbb9af94..4a5e136f8fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/987.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/987.json
@@ -1 +1 @@
-{"SOLIRIS": 14.841952018907833, "XOFIGO": 168.24900498148753}
\ No newline at end of file
+{"CLOPIDOGREL": 9.548688321080444, "null": 1.5602563385009975}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9870.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9870.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9871.json
new file mode 100644
index 00000000000..a92b107d973
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9871.json
@@ -0,0 +1 @@
+{"ATRIPLA": 0.3736498109826142, "BYDUREON": 3.827977607816139, "BYETTA": 4.505551160562772, "CLOPIDOGREL": 8.273181587297264, "COMIRNATY": 0.0314241959739542, "ELIQUIS": 2.421984324985317, "JANUMET": 19.202760364003048, "JANUVIA": 15.006842997796722, "JARDIANCE": 5.0796785907936, "PEGASYS": 0.8406553279285028, "SUTENT": 2.1532617621033867, "TOVIAZ": 10.84742633209079, "VIAGRA": 24.74928990905141, "ZOSTAVAX": 5.841992293425759, "null": 1.200179012496125}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9872.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9872.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9873.json
new file mode 100644
index 00000000000..4158870ff3e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9873.json
@@ -0,0 +1 @@
+{"FORSTEO": 59.85738486807363, "null": 0.4583349584109148}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9874.json
new file mode 100644
index 00000000000..86d69c6c8cf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9874.json
@@ -0,0 +1 @@
+{"KEYTRUDA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9875.json
new file mode 100644
index 00000000000..81333c6a86b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9875.json
@@ -0,0 +1 @@
+{"ENOXAPARIN": 299.41449900669267, "null": 2.8242185778689697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9876.json
new file mode 100644
index 00000000000..91b45a1547c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9876.json
@@ -0,0 +1 @@
+{"null": 0.5143145869086995}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9877.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9877.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9878.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9878.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9879.json
new file mode 100644
index 00000000000..2ff399ee7c6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9879.json
@@ -0,0 +1 @@
+{"null": 1.9659990130617704}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/988.json
index e389226c77b..7cbb303064f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/988.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/988.json
@@ -1 +1 @@
-{"ABACAVIR": 1.2537485406079576, "ACTOS": 2.145710677522501, "AFINITOR": 1.538627955307177, "ALIMTA": 1.7208317195612248, "ALOXI": 11.42816061559514, "AMIKACIN": 1.2298559473061583, "AMINOSALICYLIC": 1.2463078198579214, "APROVEL": 1.5032301903427945, "APTIVUS": 10.626364852276328, "ARIPIPRAZOLE": 1.2964117109713542, "ARIXTRA": 3.456069793688746, "ASPARAGINASE": 3.5001837360849595, "ATAZANAVIR": 1.3345128324242457, "AVANDIA": 2.3835883387006183, "AVASTIN": 1.0569288692131915, "AXITINIB": 1.4535378332827904, "AZATHIOPRINE": 1.2914939725272092, "BARACLUDE": 6.223079080843263, "BASILIXIMAB": 2.0495281416641, "BEDAQUILINE": 1.629802327852791, "BETAFERON": 1.1732241108484915, "BEVACIZUMAB": 1.3342719934697729, "CAELYX": 2.0265810399343835, "CANCIDAS": 13.713780090403658, "CAPECITABINE": 1.1940689299485547, "CASPOFUNGIN": 6.283481770821517, "CELECOXIB": 2.764220085297792, "CELLCEPT": 1.8956892737842224, "CICLOSPORIN": 1.3986279233932772, "COMBIVIR": 1.7161101608902585, "COMTAN": 3.678638292998556, "COTELLIC": 4.519842431229907, "CRIXIVAN": 3.672133107400042, "CUBICIN": 4.006933761777246, "CYMBALTA": 1.4106700135262575, "DABRAFENIB": 1.565296473834356, "DARUNAVIR": 2.0225237737088406, "DASATINIB": 3.63460650735159, "DELAMANID": 2.078750332025528, "DENOSUMAB": 4.068678751703394, "EBIXA": 2.568667128763497, "EFAVIRENZ": 1.253008976079394, "EMTRICITABINE": 4.357577160408731, "EPIVIR": 5.688429452210458, "ESMYA": 2.2014919438860185, "EUCREAS": 1.823849910236666, "EVENITY": 2.774168954891828, "EVEROLIMUS": 2.077306977926209, "EVISTA": 1.1194289896524332, "EXJADE": 5.117297254549858, "FILGRASTIM": 1.194467720388811, "FORSTEO": 5.74986346288816, "FULVESTRANT": 2.154862427453137, "GALVUS": 2.6738826119177266, "GLIBENCLAMIDE": 2.1133991457305017, "GLIVEC": 2.255657290512484, "HEPSERA": 28.16834807378762, "HYCAMTIN": 3.106180453629597, "ICLUSIG": 1.0634649336561652, "IRBESARTAN": 1.2994345208776243, "IRESSA": 1.6717800793693434, "IRINOTECAN": 1.0671402471896192, "ISENTRESS": 1.6033072965156916, "JAKAVI": 1.2134564009445816, "KAFTRIO": 9.739479640647222, "KALETRA": 1.27492037485358, "KEPPRA": 1.1857962093322505, "KISQALI": 3.525878313786228, "LAMIVUDINE": 2.0771486282320777, "LEFLUNOMIDE": 1.1208278606997302, "LEVOFLOXACIN": 1.3731737693909876, "LOPINAVIR": 2.5878602535121797, "MANNITOL": 7.087680750848746, "MEKINIST": 1.4920966447474768, "MICARDIS": 3.519377595266276, "MIMPARA": 1.806421874824415, "MULTAQ": 7.366273034055711, "NEXAVAR": 1.3165815154522718, "NORVIR": 1.671409421544366, "NOVONORM": 2.420845792026028, "NOXAFIL": 3.31284119327257, "OCALIVA": 26.190048824191013, "OFEV": 1.1680945551929376, "OLANZAPINE": 1.127541329854475, "OLYSIO": 2.070767466038057, "OPDIVO": 1.036833391174093, "ORKAMBI": 1.9851108393921963, "PACLITAXEL": 1.4040424373264069, "PANTOPRAZOLE": 1.958144219547391, "PAZOPANIB": 2.1979120649952697, "PREOTACT": 23.79542210462477, "PROTELOS": 5.092025947720859, "RAPAMUNE": 1.1488773325460089, "RASILEZ": 1.0049549425206583, "REMDESIVIR": 3.67356092029822, "REYATAZ": 2.1974001787726, "RIBOCICLIB": 4.309969433314161, "RUBRACA": 2.566268309356594, "SOMATROPIN": 3.775187826782616, "STIVARGA": 2.4160293558668413, "STOCRIN": 10.51552654387456, "TAMIFLU": 1.5578702045518402, "TASIGNA": 1.747508151381107, "TENOFOVIR": 2.867471441805755, "TOBRAMYCIN": 2.270878993529436, "TORISEL": 3.923368540893705, "TRACLEER": 22.12681368373806, "VFEND": 10.306379197647791, "VIRAMUNE": 3.955033721033424, "VIREAD": 1.1937158370607956, "VORICONAZOLE": 7.136350447736459, "VOTRIENT": 2.570788700297784, "XALKORI": 2.523291377501947, "XOFIGO": 8.514820350451952, "YONDELIS": 7.09801570466784, "ZOMETA": 2.9294284995589384, "ZYPREXA": 3.062838422163804, "null": 2.1058511218659026}
\ No newline at end of file
+{"null": 2.159906887486472}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9880.json
new file mode 100644
index 00000000000..20d4b864835
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9880.json
@@ -0,0 +1 @@
+{"null": 2.778200114793397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9881.json
new file mode 100644
index 00000000000..cee9219e882
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9881.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.7633851341718, "SPIKEVAX": 1.3071281457412125, "null": 0.2856277738816383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9882.json
new file mode 100644
index 00000000000..cf860035071
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9882.json
@@ -0,0 +1 @@
+{"null": 1.1765281003619523}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9883.json
new file mode 100644
index 00000000000..63a268a82b6
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9883.json
@@ -0,0 +1 @@
+{"null": 1.860314501946508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9884.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9884.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9885.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9885.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9886.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9886.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9887.json
new file mode 100644
index 00000000000..e27ad95c9bd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9887.json
@@ -0,0 +1 @@
+{"null": 0.4089667509150684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9888.json
new file mode 100644
index 00000000000..416b984744d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9888.json
@@ -0,0 +1 @@
+{"NEXAVAR": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9889.json
new file mode 100644
index 00000000000..ca335229b34
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9889.json
@@ -0,0 +1 @@
+{"NEXAVAR": 369.74579649025935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/989.json
index 0a8bf72a981..9fe30d6e591 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/989.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/989.json
@@ -1 +1 @@
-{"SPIKEVAX": 39.35756489622921}
\ No newline at end of file
+{"ALISKIREN": 138.53229877082163, "APIDRA": 7.867201110321627, "AVANDAMET": 18.58232363788637, "AVANDIA": 12.997503544288795, "BYETTA": 2.295696457985284, "CHAMPIX": 0.9864189189266724, "CLOPIDOGREL": 1.8742822212536447, "COMIRNATY": 0.284915905480668, "DALIRESP": 42.69625338462652, "DASATINIB": 19.304223782686, "ELIQUIS": 2.103774375572046, "ENTRESTO": 1.3660595719170066, "EXFORGE": 5.835231522706204, "FORSTEO": 1.1170321285207196, "FORXIGA": 4.376216116312304, "HUMALOG": 6.249195683101624, "HUMIRA": 1.4350813085502738, "ICLUSIG": 6.678339062934668, "INSULIN": 2.361419941845703, "JANUMET": 3.055857161467437, "JARDIANCE": 1.8502278515873103, "LANTUS": 3.07047876277982, "LEVEMIR": 4.451726847975972, "NILOTINIB": 10.465354402752332, "PEGASYS": 0.3157662611065434, "PLAVIX": 4.986987747410097, "SOMAVERT": 61.40886252165932, "SPIKEVAX": 0.0978930769053573, "STELARA": 0.6052998801531039, "SUTENT": 0.6614113648860859, "TASIGNA": 13.054167595689412, "TOZINAMERAN": 0.2535036764857653, "VAXZEVRIA": 0.137960541382642, "VIAGRA": 6.504272692991568, "XELJANZ": 0.7435249472830961, "null": 1.3749397789427116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9890.json
new file mode 100644
index 00000000000..d09b338e521
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9890.json
@@ -0,0 +1 @@
+{"ATRIPLA": 43.59832683357723, "KALETRA": 7.672604103051006, "STRIBILD": 38.08103452661691, "TRUVADA": 68.75035750194012, "VIREAD": 15.633383854024098, "null": 0.0480203407632332}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9891.json
new file mode 100644
index 00000000000..863c0647baf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9891.json
@@ -0,0 +1 @@
+{"AFINITOR": 6.586279086080081, "COMIRNATY": 0.2005563914762491, "DEXAMETHASONE": 2.0551905742722383, "ESOMEPRAZOLE": 8.990638327034405, "EXJADE": 14.599246450086667, "HYCAMTIN": 39.56100020244674, "IBRANCE": 1.423870112673141, "KEYTRUDA": 1.3694342697983286, "KYMRIAH": 9.225437549353147, "MEKINIST": 6.382971216404859, "PEGASYS": 0.6833074882280151, "PEGINTRON": 1.838399102536998, "SUTENT": 3.1244395552488444, "VFEND": 4.426889385910149, "XALKORI": 9.520158694719164, "null": 1.267054999236775}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9892.json
new file mode 100644
index 00000000000..34e5eb847b9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9892.json
@@ -0,0 +1 @@
+{"ATRIPLA": 18.384247537775146, "CAPECITABINE": 13.137836229531482, "COMIRNATY": 0.0719243856830426, "ERIBULIN": 183.550213263826, "EXJADE": 5.443680301476359, "SPINRAZA": 13.204125319543, "STRIBILD": 16.158653148413833, "SUTENT": 0.6962711437099669, "TRUVADA": 22.18963464029907, "null": 0.5637002949079023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9893.json
new file mode 100644
index 00000000000..3639e77b8d5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9893.json
@@ -0,0 +1 @@
+{"AVASTIN": 26.29264882483542, "COMIRNATY": 0.1844796665064109, "JARDIANCE": 5.0801639009876896, "KEYTRUDA": 13.279468739183656, "SUTENT": 1.8975761612953617, "null": 0.9756239754048271}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9894.json
new file mode 100644
index 00000000000..4a95ec69cec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9894.json
@@ -0,0 +1 @@
+{"AFINITOR": 1.824890509127127, "ATRIPLA": 5.3952579325425045, "AVASTIN": 7.222063625544352, "BENLYSTA": 3.997195001964161, "BEVACIZUMAB": 6.145699588166835, "CABOMETYX": 12.793053284807993, "CELLCEPT": 2.702731626954584, "CICLOSPORIN": 5.849815474170696, "COMIRNATY": 0.091436501967123, "ENTECAVIR": 42.48409458101086, "EXJADE": 4.064352527770911, "HEPSERA": 28.01542513836638, "INLYTA": 8.561011414028785, "KEYTRUDA": 3.671621383980899, "LANTUS": 1.058041622579815, "LEMTRADA": 8.542987368196941, "LENVIMA": 22.02907929843787, "NEXAVAR": 2.79279986788058, "SOLIRIS": 2.1575844695219235, "SPINRAZA": 10.162907183565522, "STIVARGA": 13.60207694931976, "STRIBILD": 12.203197917789748, "SUTENT": 3.3680442571527114, "TOZINAMERAN": 0.1703562759002708, "TRUVADA": 7.082237197250877, "VOTRIENT": 2.477851817494573, "null": 0.7706493762305683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9895.json
new file mode 100644
index 00000000000..5acf814c9a4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9895.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 8.750472716190513, "SOMATROPIN": 185.394968085309, "null": 1.5746187020756708}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9896.json
new file mode 100644
index 00000000000..8dad1437b75
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9896.json
@@ -0,0 +1 @@
+{"ABACAVIR": 1.4749559325424944, "AFINITOR": 1.664651264313887, "AFLIBERCEPT": 14.5899979923462, "ALEMTUZUMAB": 1.631001678070005, "ALIMTA": 0.6104647031243601, "ARAVA": 0.0873793655195541, "ATAZANAVIR": 2.7311007328437404, "ATRIPLA": 5.921561926870156, "AVASTIN": 14.587322598909042, "AXITINIB": 10.716961163246502, "AZATHIOPRINE": 1.937428357090326, "BASILIXIMAB": 5.278645075495335, "BAVENCIO": 9.551171466749564, "BENLYSTA": 2.1200644818300947, "BETAFERON": 1.8707144237316888, "BEVACIZUMAB": 15.38663158442377, "BIKTARVY": 1.1184052546047203, "BORTEZOMIB": 1.3729002596103292, "BRAFTOVI": 0.8033066982315499, "BUSULFAN": 0.7436549541869343, "BYDUREON": 0.800945384291209, "BYETTA": 0.3369433707183722, "CABOMETYX": 26.78536542414077, "CELLCEPT": 4.0212275551435015, "CICLOSPORIN": 7.082994895658917, "COMBIVIR": 1.1028444174078205, "COMIRNATY": 0.1094793689240772, "COSENTYX": 0.2585715924241102, "CRIXIVAN": 2.752359486201103, "CYRAMZA": 21.88696057678864, "DACLATASVIR": 3.5154205941141465, "DARUNAVIR": 5.61177053335957, "DASATINIB": 2.612603248618689, "DEXAMETHASONE": 0.3293359266242752, "EFAVIRENZ": 1.2959874576200885, "ELIQUIS": 0.1124346419286731, "EMTRICITABINE": 6.503786909132362, "ENTECAVIR": 6.678567825246477, "ENTRESTO": 0.7195284840451446, "ENTYVIO": 0.5385797314086693, "EPIVIR": 1.7788240670186852, "EVEROLIMUS": 2.148518889400526, "EXJADE": 5.915398565375088, "FORXIGA": 1.3178250067455797, "GALAFOLD": 10.428904441011738, "GALVUS": 1.4586321416950163, "GARDASIL": 0.1968249244181083, "HARVONI": 1.758370113279903, "HEPSERA": 13.164315772820816, "HUMALOG": 0.3665788623840192, "HUMIRA": 0.4826776607474746, "IBUPROFEN": 1.753387115562807, "ICLUSIG": 1.023516051091331, "INLYTA": 11.840970594423409, "INSULIN": 1.3536122492420108, "IRINOTECAN": 3.5848223778884454, "JAKAVI": 0.5158118376955237, "JANUVIA": 0.5949396174793772, "JARDIANCE": 0.3845475925174696, "KALETRA": 2.612833425096884, "KEYTRUDA": 13.23385737812034, "LAMIVUDINE": 4.448180624175497, "LANTUS": 0.3423782611593189, "LEMTRADA": 2.2707625252706496, "LENVIMA": 62.09274455717696, "LEVETIRACETAM": 0.3871718473370532, "LEVOFLOXACIN": 0.4312199681340115, "LONSURF": 1.123250263870803, "LOPINAVIR": 3.821691489808856, "LUPKYNIS": 45.94678797603984, "LYNPARZA": 0.8991903891171236, "METFORMIN": 7.345176640142861, "METHOTREXATE": 0.6621191587416887, "MICARDIS": 1.1133128288894707, "MIDAZOLAM": 1.2068767657197006, "MYCOPHENOLATE": 5.134486465657435, "NEXAVAR": 4.354487559138087, "NORVIR": 7.953206706559948, "OLANZAPINE": 0.2633075401185435, "OPDIVO": 0.5298961071481234, "OZEMPIC": 3.982016142742893, "PAZOPANIB": 9.60978881754176, "PEGASYS": 0.1872845309417554, "PEGINTERFERON": 0.4781283173392901, "PEGINTRON": 0.2551272691321955, "PEMBROLIZUMAB": 4.052412746862008, "PEMETREXED": 2.8281726182896776, "PLAVIX": 0.2038656099356963, "RAPAMUNE": 11.55672689708816, "RASILEZ": 9.098022280081588, "REYATAZ": 2.8791696134844176, "RIBAVIRIN": 1.015676576563272, "ROACTEMRA": 0.6260227554204189, "SOLIRIS": 6.013348570133013, "SPIKEVAX": 0.0690465370416721, "SPINRAZA": 7.17713036823594, "SPRYCEL": 1.3537959407081843, "STELARA": 0.359012631378443, "STIVARGA": 9.854963822550864, "STRIBILD": 4.7347056716076406, "SUNITINIB": 9.455354143398926, "SUTENT": 2.802689389608265, "TAMIFLU": 4.573017070850496, "TELMISARTAN": 2.89361043441058, "TENOFOVIR": 24.1606279256998, "TIVICAY": 2.5393731250062097, "TOZINAMERAN": 0.1071381571406256, "TRUVADA": 6.813157290886251, "VAXZEVRIA": 0.0279817320424352, "VIREAD": 13.078849431429168, "VOTRIENT": 6.281423010616346, "XOLAIR": 0.3229057734735651, "ZALTRAP": 34.85095200530019, "ZOSTAVAX": 0.2363523623854611, "ZYPREXA": 0.6752475642344596, "null": 0.5790996767566278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9897.json
new file mode 100644
index 00000000000..c5f9d40b427
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9897.json
@@ -0,0 +1 @@
+{"AMIKACIN": 120.9803622922906, "null": 0.3057232388982975}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9898.json
new file mode 100644
index 00000000000..c7722da420e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9898.json
@@ -0,0 +1 @@
+{"null": 1.9046738537938133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9899.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9899.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/99.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/99.json
index 54d4b7a6c22..91f607b2cac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/99.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/99.json
@@ -1 +1 @@
-{"NOXAFIL": 2864.886879155343}
\ No newline at end of file
+{"null": 1.7549413295032312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/990.json
index 05aa0640833..5673fd06eaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/990.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/990.json
@@ -1 +1 @@
-{"GARDASIL": 27.869754761488355, "null": 2.415129997857277}
\ No newline at end of file
+{"ELTROMBOPAG": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9900.json
new file mode 100644
index 00000000000..b768faefc7b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9900.json
@@ -0,0 +1 @@
+{"null": 1.295099442722168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9901.json
new file mode 100644
index 00000000000..c935e26d793
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9901.json
@@ -0,0 +1 @@
+{"COMBIVIR": 8.294196364349702, "ELIQUIS": 1.04009288122249, "PLAVIX": 2.090735024750122, "null": 7.047693646526709}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9902.json
new file mode 100644
index 00000000000..59afd406723
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9902.json
@@ -0,0 +1 @@
+{"null": 3.7623352939256782}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9903.json
new file mode 100644
index 00000000000..07d7b04b186
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9903.json
@@ -0,0 +1 @@
+{"VAXZEVRIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9904.json
new file mode 100644
index 00000000000..030666f2ec4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9904.json
@@ -0,0 +1 @@
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9905.json
new file mode 100644
index 00000000000..9fb9bbab8d3
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9905.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9906.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9906.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9907.json
new file mode 100644
index 00000000000..6a84cdb0425
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9907.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9908.json
new file mode 100644
index 00000000000..3a976012073
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9908.json
@@ -0,0 +1 @@
+{"null": 4.112211797218636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9909.json
new file mode 100644
index 00000000000..443b0d53a0b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9909.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/991.json
index 19c062499ae..8309518f405 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/991.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/991.json
@@ -1 +1 @@
-{"null": 2.387804269380746}
\ No newline at end of file
+{"null": 0.9603570280305574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9910.json
new file mode 100644
index 00000000000..bd2f17fb4f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9910.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9911.json
new file mode 100644
index 00000000000..bae3951d25f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9911.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9912.json
new file mode 100644
index 00000000000..6752aec190f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9912.json
@@ -0,0 +1 @@
+{"TOBRAMYCIN": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9913.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9913.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9914.json
new file mode 100644
index 00000000000..726c4fa3828
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9914.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9915.json
new file mode 100644
index 00000000000..32ecdbbc14c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9915.json
@@ -0,0 +1 @@
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1.7669519995758856, "ZARZIO": 2.475754836813284, "ZEJULA": 0.7571707646726584, "ZELBORAF": 1.82387557463027, "ZEPATIER": 0.81613178398048, "ZIAGEN": 1.7661512994425843, "ZINBRYTA": 0.5421073183824189, "ZOSTAVAX": 0.5622906405861725, "ZYCLARA": 1.5911129188880275, "ZYLLT": 7.784913261371754, "ZYPADHERA": 0.1023385170010129, "ZYPREXA": 0.1496532355835211, "null": 1.7400467275980025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9916.json
new file mode 100644
index 00000000000..0ac1f7a8202
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9916.json
@@ -0,0 +1 @@
+{"ARAVA": 2.8044765664138938, "COMIRNATY": 0.6346223861379429, "ENBREL": 21.70287979022532, "SPIKEVAX": 0.1706094614303069, "null": 1.287513421438996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9917.json
new file mode 100644
index 00000000000..61bdd8be4f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9917.json
@@ -0,0 +1 @@
+{"AIMOVIG": 1.783384312562278, "APIXABAN": 8.109944435222767, "COMIRNATY": 0.216597007744693, "ELLAONE": 17.2964921881521, "EMPAGLIFLOZIN": 25.75357746727545, "FORXIGA": 78.53272962310454, "JARDIANCE": 111.4312429896425, "SPIKEVAX": 0.1121427780028493, "SUTENT": 1.3008664534347196, "VAXZEVRIA": 0.1065450399560452, "VIAGRA": 2.9465436143331285, "null": 1.089259021910829}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9918.json
new file mode 100644
index 00000000000..c130b169da8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9918.json
@@ -0,0 +1 @@
+{"EVENITY": 261.59813408667446}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9919.json
new file mode 100644
index 00000000000..ae3127c386d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9919.json
@@ -0,0 +1 @@
+{"BUDESONIDE": 15.593398400521718, "RITONAVIR": 570.5118041624851, "null": 1.8473002313619384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/992.json
index ffb67fcdeb4..e67602463fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/992.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/992.json
@@ -1 +1 @@
-{"null": 2.831712131471681}
\ No newline at end of file
+{"PLAVIX": 47.24595151381424, "null": 2.051392505486674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9920.json
new file mode 100644
index 00000000000..ea946828a29
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9920.json
@@ -0,0 +1 @@
+{"null": 6.14466261610998}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9921.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9921.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9922.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9922.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9923.json
new file mode 100644
index 00000000000..95705ee20cc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9923.json
@@ -0,0 +1 @@
+{"NOXAFIL": 411.6086505306429, "POSACONAZOLE": 792.8375288062289, "null": 1.388383917645622}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9924.json
new file mode 100644
index 00000000000..87875cac5ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9924.json
@@ -0,0 +1 @@
+{"SPIKEVAX": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9925.json
new file mode 100644
index 00000000000..d8ff5fb4e76
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9925.json
@@ -0,0 +1 @@
+{"null": 0.607446179040787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9926.json
new file mode 100644
index 00000000000..a4823d5b35d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9926.json
@@ -0,0 +1 @@
+{"PEMETREXED": 1527.0649025067391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9927.json
new file mode 100644
index 00000000000..9c10ee6c2b8
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9927.json
@@ -0,0 +1 @@
+{"null": 2.566026419329083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9928.json
new file mode 100644
index 00000000000..bfe5897cae5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9928.json
@@ -0,0 +1 @@
+{"BEVACIZUMAB": 128.19585444674448, "HALAVEN": 176.10370880440905, "null": 0.1724172538418155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9929.json
new file mode 100644
index 00000000000..e3d68d2d00d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9929.json
@@ -0,0 +1 @@
+{"null": 0.5325914553744783}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/993.json
index 128bbf04922..d84d7dd6006 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/993.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/993.json
@@ -1 +1 @@
-{"null": 1.6317463676500423}
\ No newline at end of file
+{"NEVIRAPINE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9930.json
new file mode 100644
index 00000000000..13c404c21a0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9930.json
@@ -0,0 +1 @@
+{"ESOMEPRAZOLE": 215.59962289320904, "null": 1.09696050511675}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9931.json
new file mode 100644
index 00000000000..b61748ff35e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9931.json
@@ -0,0 +1 @@
+{"EYLEA": 1819.859413821768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9932.json
new file mode 100644
index 00000000000..cd8a8aa5c7b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9932.json
@@ -0,0 +1 @@
+{"null": 1.119567934549201}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9933.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9933.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9934.json
new file mode 100644
index 00000000000..035e38537ea
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9934.json
@@ -0,0 +1 @@
+{"ORKAMBI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9935.json
new file mode 100644
index 00000000000..27758240a93
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9935.json
@@ -0,0 +1 @@
+{"null": 0.7618228783228234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9936.json
new file mode 100644
index 00000000000..a69846ea5de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9936.json
@@ -0,0 +1 @@
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9937.json
new file mode 100644
index 00000000000..9b9968c69e1
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9937.json
@@ -0,0 +1 @@
+{"BEVACIZUMAB": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9938.json
new file mode 100644
index 00000000000..1343cf28335
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9938.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 20.189460102042258, "TOZINAMERAN": 0.869239000088501, "null": 2.445645914941535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9939.json
new file mode 100644
index 00000000000..3da89422b4e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9939.json
@@ -0,0 +1 @@
+{"AMIKACIN": 6.97841915403745, "CELLCEPT": 4.955971336538646, "DIFICLIR": 47.81509754634903, "LEVOFLOXACIN": 15.047645058571865, "PANTOPRAZOLE": 7.688224126587928, "PEGINTRON": 1.0060189620392588, "TIGECYCLINE": 41.874952011277145, "TOBRAMYCIN": 46.61018151627578, "VFEND": 4.923921244898617, "null": 7.118571002259911}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/994.json
index 5a642ffd79d..949808a5196 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/994.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/994.json
@@ -1 +1 @@
-{"CICLOSPORIN": 17.381817218889044, "VFEND": 43.70566324897491, "null": 1.0457103864183634}
\ No newline at end of file
+{"CLOPIDOGREL": 10.201078083172174, "COMIRNATY": 0.2297622161382351, "null": 1.233393795380072}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9940.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9940.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9941.json
new file mode 100644
index 00000000000..69f86d3a2cb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9941.json
@@ -0,0 +1 @@
+{"AZACITIDINE": 68.5374381551583, "CICLOSPORIN": 6.195800973285566, "METHOTREXATE": 22.12902840013795, "null": 0.2967473278675824}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9942.json
new file mode 100644
index 00000000000..ff934036a25
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9942.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 14.451518585882337, "ASPARAGINASE": 319.775220112462, "BUSILVEX": 174.78341325570173, "BUSULFAN": 13.53753148283174, "CELLCEPT": 4.076770399202561, "CICLOSPORIN": 11.914783624141084, "CYTARABINE": 17.012471858250922, "DEXAMETHASONE": 7.025042258375834, "IBUPROFEN": 6.332117654840045, "ONCASPAR": 32.13838074555922, "SOLIRIS": 12.82907096358088, "null": 0.511757431714018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9943.json
new file mode 100644
index 00000000000..9f7c1e9209b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9943.json
@@ -0,0 +1 @@
+{"ALEMTUZUMAB": 15.441605146230758, "AMIKACIN": 22.172232147919782, "APIXABAN": 1.2917254950323067, "ASPARAGINASE": 12.415466277968063, "AZTREONAM": 65.86105513431144, "BASILIXIMAB": 23.609301228922348, "BENRALIZUMAB": 81.24480450677787, "BUSULFAN": 6.90218685328443, "CASPOFUNGIN": 32.45388870286651, "CELLCEPT": 4.105616766138381, "CICLOSPORIN": 11.244732820966338, "COMIRNATY": 0.0180178509616123, "CYTARABINE": 12.371061814410146, "DEXAMETHASONE": 6.60750977446022, "DOXORUBICIN": 3.812937353762629, "EXJADE": 1.5805926948000562, "FENTANYL": 1.2856183194947242, "GANCICLOVIR": 12.41252544005707, "HIZENTRA": 5.666037560804693, "HUMIRA": 2.75240673640999, "IBUPROFEN": 3.130919492115618, "KAFTRIO": 10.939506083212557, "KALYDECO": 30.343285991339783, "KEYTRUDA": 0.6063277143139286, "LEVOFLOXACIN": 4.152333735630167, "METHOTREXATE": 1.9914827810765383, "MYCOPHENOLATE": 23.508561960276364, "ORKAMBI": 59.52932317879984, "REMICADE": 6.979032959489842, "RITUXIMAB": 3.247001363894992, "SOLIRIS": 6.819466328999691, "SPINRAZA": 8.923477398241392, "TOBRAMYCIN": 51.875778004570485, "TRACLEER": 1.9134686213044036, "TRELEGY": 3.299212319100626, "VORICONAZOLE": 4.730976282542804, "XELJANZ": 0.6490969551117982, "XOLAIR": 1.1717374517320758, "null": 0.9068339111027156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9944.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9944.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9945.json
new file mode 100644
index 00000000000..6780ed8cbe7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9945.json
@@ -0,0 +1 @@
+{"null": 0.6875802522490944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9946.json
new file mode 100644
index 00000000000..1d75867a333
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9946.json
@@ -0,0 +1 @@
+{"DARZALEX": 214.1076754529604, "null": 2.6942395959759136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9947.json
new file mode 100644
index 00000000000..b2b3a423453
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9947.json
@@ -0,0 +1 @@
+{"GARDASIL": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9948.json
new file mode 100644
index 00000000000..04de03f1968
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9948.json
@@ -0,0 +1 @@
+{"null": 2.47115983700277}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9949.json
new file mode 100644
index 00000000000..cff90208816
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9949.json
@@ -0,0 +1 @@
+{"ZOSTAVAX": 122.52777325264674, "null": 0.3476500171942541}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/995.json
index ba76e959e7f..0e769d31fc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/995.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/995.json
@@ -1 +1 @@
-{"JARDIANCE": 33.38899182601525, "null": 1.6691528772302124}
\ No newline at end of file
+{"KALETRA": 60.86101401802448, "null": 1.2134626670204665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9950.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9950.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9951.json
new file mode 100644
index 00000000000..0e1099b0de0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9951.json
@@ -0,0 +1 @@
+{"null": 0.4795028478921596}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9952.json
new file mode 100644
index 00000000000..8723e6e9dec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9952.json
@@ -0,0 +1 @@
+{"VFEND": 128.6672897321775, "VORICONAZOLE": 300.1623556152388, "null": 1.5264972211652248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9953.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9953.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9954.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9954.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9955.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9955.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9956.json
new file mode 100644
index 00000000000..939e1878b67
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9956.json
@@ -0,0 +1 @@
+{"null": 0.5404806822656967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9957.json
new file mode 100644
index 00000000000..b810b2f977d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9957.json
@@ -0,0 +1 @@
+{"CIMZIA": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9958.json
new file mode 100644
index 00000000000..a69846ea5de
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9958.json
@@ -0,0 +1 @@
+{"null": 3.61249888498465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9959.json
new file mode 100644
index 00000000000..cf063014941
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9959.json
@@ -0,0 +1 @@
+{"KEYTRUDA": 4.57827698607372, "PEGASYS": 4.096950187522695, "PEGINTRON": 8.689713970945844, "null": 0.6599722030172953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/996.json
index 5f2d661fd2f..503529ce40e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/996.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/996.json
@@ -1 +1 @@
-{"ABACAVIR": 2.735628081751657, "ABILIFY": 9.1049112387039, "EXJADE": 5.665182473005377, "HYDROCORTISONE": 12.969970740445046, "IBUPROFEN": 6.4731692348201335, "JARDIANCE": 3.3973972552316525, "MIDAZOLAM": 11.685211860895532, "OLANZAPINE": 3.054626961801964, "SPIRONOLACTONE": 18.995486497641668, "TENOFOVIR": 55.16388215135517, "null": 2.0747068772987305}
\ No newline at end of file
+{"AVANDIA": 6.678563257384186, "COMIRNATY": 0.1985628827169647, "HUMALOG": 4.071161585150862, "TASIGNA": 28.637597958323, "null": 0.8455261551881937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9960.json
new file mode 100644
index 00000000000..0dbccd4c4f5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9960.json
@@ -0,0 +1 @@
+{"ABACAVIR": 22.82069497717423, "ABATACEPT": 0.4598788078149544, "ABILIFY": 0.8689452782888392, "ADALIMUMAB": 1.560320862659625, "AFINITOR": 0.2110998211011514, "AIMOVIG": 0.3470076782307491, "ALIMTA": 0.2805429902422057, "AMGEVITA": 41.23265456712485, "AMINOSALICYLIC": 0.365594612709599, "ANAKINRA": 2.0130295410139385, "APIDRA": 0.3467024932535977, "APREMILAST": 1.6825195823750554, "ARAVA": 0.6305539297254313, "ARIPIPRAZOLE": 0.5457875445064282, "ATAZANAVIR": 0.811202773100009, "AUBAGIO": 0.7192437373440937, "AVONEX": 3.366688255638063, "AZATHIOPRINE": 0.7062356984368858, "BENLYSTA": 0.3261437372910199, "BRODALUMAB": 38.37623437383036, "BUPRENORPHINE": 0.4378802397556409, "BYETTA": 0.2221011080959943, "CARIPRAZINE": 9.92761212615132, "CELECOXIB": 2.4001400884204487, "CHAMPIX": 1.1331116181480096, "CICLOSPORIN": 4.634165099903805, "CIMZIA": 10.59391422304764, "CLOPIDOGREL": 0.6167185824785225, "COMIRNATY": 0.4574265602967206, "COSENTYX": 39.91171309841813, "CYMBALTA": 0.0794807425158383, "DAPAGLIFLOZIN": 6.38472549246734, "DULOXETINE": 0.618461827097194, "DUPIXENT": 3.623032255377798, "ELIQUIS": 0.2695348258974694, "EMPAGLIFLOZIN": 1.6786122625399438, "ENBREL": 7.007337123580148, "ENTYVIO": 1.976477305051341, "ESBRIET": 0.3868811598011796, "EXFORGE": 0.4306158260424604, "FASENRA": 0.5223952831105989, "FORSTEO": 0.2673430871830812, "GARDASIL": 0.2244048527799011, "GOLIMUMAB": 17.33678070325074, "GUSELKUMAB": 19.823778766041663, "HUMALOG": 0.1815264207521245, "HUMIRA": 13.135154330538048, "HYDROCORTISONE": 0.967116999033196, "IBRANCE": 0.1150208812784164, "IBUPROFEN": 0.8990637031878023, "IDACIO": 25.684053552221773, "INCIVO": 0.8479338649083897, "INFLIXIMAB": 4.077207811533406, "INLYTA": 0.3474547607783309, "IRBESARTAN": 0.5895283284966372, "IVABRADINE": 22.570009125551728, "JANUMET": 0.5465470537999638, "JANUVIA": 0.2992471053806052, "JARDIANCE": 0.3354518956619081, "KEPPRA": 0.1658214148513378, "KEYTRUDA": 1.6062493438121328, "LANTUS": 0.0745451011129126, "LEFLUNOMIDE": 3.5272663669278144, "MAVENCLAD": 1.876112664922628, "MEKINIST": 0.2847942320008498, "MEPOLIZUMAB": 0.2064027426625358, "METHOTREXATE": 4.475626192928546, "MICARDIS": 0.4989359015679259, "MODERNA": 0.5356519226319324, "NEXAVAR": 0.5016513870541368, "NUCALA": 0.425033014272089, "OLANZAPINE": 0.1092357630053982, "OMALIZUMAB": 0.2590194474933648, "OPDIVO": 0.4006117020417057, "OTEZLA": 38.38255102083125, "PANTOPRAZOLE": 0.4329274846550134, "PEGASYS": 2.3397961595430514, "PEGINTERFERON": 2.5079651191003878, "PEGINTRON": 1.3165271681672537, "PEMBROLIZUMAB": 2.412047978438032, "PLAVIX": 0.1186722420827932, "REMICADE": 4.663771121219916, "RIBAVIRIN": 0.5420355308278877, "RINVOQ": 3.446990237333143, "RISANKIZUMAB": 64.94692932419719, "ROACTEMRA": 2.285435652893539, "SHINGRIX": 0.3726344855931676, "SIMPONI": 8.79676414085615, "SKYRIZI": 52.66322628834445, "SPIKEVAX": 0.3713409107050997, "STELARA": 37.58019488748864, "SUTENT": 0.0720511150400457, "TASIGNA": 0.2919814359733627, "TOCILIZUMAB": 1.6846816793288026, "TOZINAMERAN": 0.5529735674432807, "TREMFYA": 56.59049580859468, "TRULICITY": 0.2688171196841118, "TWINRIX": 0.98912767556605, "USTEKINUMAB": 19.47108059867133, "VAXZEVRIA": 0.2733562654263586, "VICTOZA": 0.3211227409324262, "XELJANZ": 1.0289455714703095, "XOLAIR": 0.5578471156452433, "XTANDI": 0.147383826139639, "ZINBRYTA": 5.849242037953012, "ZOSTAVAX": 0.6920831381742979, "ZYPREXA": 0.1181638546468332, "null": 0.3652686413115424}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9961.json
new file mode 100644
index 00000000000..e64bb13ba4d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9961.json
@@ -0,0 +1 @@
+{"CICLOSPORIN": 17.602866853653254, "COSENTYX": 80.16842056334167, "STELARA": 79.88599567142282, "TREMFYA": 113.32664811585596, "null": 0.1572185718919271}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9962.json
new file mode 100644
index 00000000000..2de3762be5c
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9962.json
@@ -0,0 +1 @@
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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9963.json
new file mode 100644
index 00000000000..23eb2aeffff
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9963.json
@@ -0,0 +1 @@
+{"ABILIFY": 9.609835919802954, "ARIPIPRAZOLE": 7.0087054985813655, "ATAZANAVIR": 863.8107365301199, "CHAMPIX": 5.554664792548061, "COMIRNATY": 0.0486338702628282, "ENFUVIRTIDE": 296.7536430572005, "ISENTRESS": 43.90216758095309, "KEPPRA": 5.9825798722112005, "LATUDA": 8.074227299509102, "OLANZAPINE": 14.850982788854028, "RALTEGRAVIR": 663.2396778811935, "ZYPREXA": 8.906618439569613, "null": 0.5651913877276963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9964.json
new file mode 100644
index 00000000000..193236494b0
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9964.json
@@ -0,0 +1 @@
+{"TAMIFLU": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9965.json
new file mode 100644
index 00000000000..b7737f1a6b2
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9965.json
@@ -0,0 +1 @@
+{"ABILIFY": 5.61354257059456, "ARAVA": 0.185173479055137, "ARIPIPRAZOLE": 2.9268302724957804, "ATRIPLA": 0.3077756151230046, "BIKTARVY": 2.997034679642722, "CHAMPIX": 10.780484138968731, "CICLOSPORIN": 0.6256028991085871, "COMIRNATY": 0.1016751045803289, "COMTAN": 15.043310369274588, "CYMBALTA": 1.079595988435905, "DOLUTEGRAVIR": 29.68566372575558, "FENTANYL": 2.1460486910167824, "FYCOMPA": 8.522408418008784, "GARDASIL": 0.6685770315074528, "IBRANCE": 1.912382149099341, "KALETRA": 3.209432723902557, "KEPPRA": 2.3918112724497536, "LATUDA": 15.73146219237784, "LEVETIRACETAM": 7.15761083068843, "LYRICA": 1.84186765198974, "NUCALA": 5.275976231333815, "OLANZAPINE": 5.07864707993174, "PANTOPRAZOLE": 3.351864447067106, "PEGASYS": 1.4917743932836192, "PEGINTRON": 3.281670866273176, "SPIKEVAX": 0.1211970256133943, "TAMIFLU": 7.817796259819365, "TOZINAMERAN": 0.2823848263375736, "VAXZEVRIA": 0.0629836928820213, "VFEND": 4.058998513201081, "XEPLION": 61.4738604159204, "ZYPREXA": 6.873586095912122, "null": 1.861010739411855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9966.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9966.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9967.json
new file mode 100644
index 00000000000..a2eaa375c81
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9967.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.0660217338168376, "CYMBALTA": 4.744617226483364, "GARDASIL": 8.852669974974052, "KEPPRA": 13.89667117744226, "LEVETIRACETAM": 19.69329021393718, "TOZINAMERAN": 0.9719971400051576, "VAXZEVRIA": 0.1836147890463464, "null": 0.9024895054077552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9968.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9968.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9969.json
new file mode 100644
index 00000000000..b0cfb77bc4f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9969.json
@@ -0,0 +1 @@
+{"COMIRNATY": 0.1327987290627705, "PLAVIX": 36.86454495297246, "TAXOTERE": 231.20972511778865, "VAXZEVRIA": 0.2484876424268287, "null": 1.5107688625169726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/997.json
index dbf92847201..08fc740df1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/997.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/997.json
@@ -1 +1 @@
-{"null": 1.385752609194561}
\ No newline at end of file
+{"null": 1.0961520086560907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9970.json
new file mode 100644
index 00000000000..bbbb1d4dc88
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9970.json
@@ -0,0 +1 @@
+{"ABILIFY": 4.155866645617641, "AERIUS": 5.559014933000945, "ARAVA": 0.1356833554361043, "ARIPIPRAZOLE": 5.780051026120516, "ATRIPLA": 0.0604318783064555, "AVAMYS": 2.186908483662413, "BRINTELLIX": 5.592674637258802, "BRIVIACT": 7.344484520443719, "BUDESONIDE": 0.7321401269024209, "BUPRENORPHINE": 1.0604832253808596, "CHAMPIX": 2.040452614911113, "CICLOSPORIN": 0.4411359405400969, "COMIRNATY": 0.135854734249443, "COMTAN": 13.85202409203312, "CYMBALTA": 2.232905787936908, "DEXAMETHASONE": 0.8040700132099007, "EBIXA": 6.6408419273953205, "ENTACAPONE": 8.648030355705465, "FAMPYRA": 1.9876498921068295, "FENTANYL": 1.9532639469149984, "FIRDAPSE": 2.2365288014895577, "FYCOMPA": 4.175707236722924, "GARDASIL": 0.7037727063327088, "HUMALOG": 0.3290262440269996, "IBUPROFEN": 0.6515350703473411, "INFANRIX": 4.008571072691341, "KAFTRIO": 5.674357201283271, "KEPPRA": 5.175654534071547, "LANTUS": 0.245188629128202, "LATUDA": 5.5265487070963255, "LEVETIRACETAM": 5.534581183387951, "LEVOFLOXACIN": 0.6430357242251024, "LYRICA": 2.197467492393769, "MEMANTINE": 7.74236912757044, "MIDAZOLAM": 5.473343443014742, "MMRVAXPRO": 0.9727515628089224, "OCRELIZUMAB": 1.0935977350540669, "OLANZAPINE": 5.806905559199685, "PEGASYS": 0.1359624884539184, "PEGINTRON": 1.2619139731689897, "SIFROL": 17.703927955028576, "SPIKEVAX": 0.0730956313773237, "STALEVO": 11.438706786685517, "SUBOXONE": 4.977229960777053, "SYCREST": 13.138707361169436, "TAMIFLU": 2.567256030938045, "TOZINAMERAN": 0.1736887640741186, "VAXZEVRIA": 0.1319638624169457, "VFEND": 1.46545288704676, "XYREM": 3.042325868507257, "ZYPADHERA": 18.421043368971645, "ZYPREXA": 3.752343607136511, "null": 3.32270081967387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9971.json
new file mode 100644
index 00000000000..edac42f6a1b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9971.json
@@ -0,0 +1 @@
+{"ABILIFY": 4.694678166947435, "ARIPIPRAZOLE": 9.64151384720076, "ATAZANAVIR": 40.66560513169935, "COMIRNATY": 0.036348164215083, "CYMBALTA": 0.8863228144255121, "KEPPRA": 2.7540945547788565, "LEVETIRACETAM": 2.175933810464027, "OLANZAPINE": 12.184443717760209, "SPIKEVAX": 0.0984009218757169, "ZYPREXA": 5.2300472652238135, "null": 3.972347605089073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9972.json
new file mode 100644
index 00000000000..18e4858a0ec
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9972.json
@@ -0,0 +1 @@
+{"ABILIFY": 4.580325375712034, "ATAZANAVIR": 301.8093503692099, "BUPRENORPHINE": 2.2431788009353664, "COMIRNATY": 0.0527243506074238, "CYMBALTA": 0.7249368761476956, "ENFUVIRTIDE": 135.3868717632304, "INFANRIX": 17.122759786610846, "KEPPRA": 4.90304105734804, "LEVETIRACETAM": 2.5014008895168494, "MMRVAXPRO": 1.3957471703696571, "OLANZAPINE": 1.9600758786264283, "SUTENT": 0.4564353745234532, "null": 3.326206645240091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9973.json
new file mode 100644
index 00000000000..de33cf8e420
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9973.json
@@ -0,0 +1 @@
+{"null": 1.2678387061803291}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9974.json
new file mode 100644
index 00000000000..98ec826b71b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9974.json
@@ -0,0 +1 @@
+{"null": 3.497918662723256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9975.json
new file mode 100644
index 00000000000..25df9691e3b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9975.json
@@ -0,0 +1 @@
+{"BUMETANIDE": 171.91699021283188, "BUPRENORPHINE": 7.996880316394824, "CHAMPIX": 9.268239703141166, "COMTAN": 51.64729196331477, "CYMBALTA": 2.6989143462109286, "FENTANYL": 5.727365350946863, "KEPPRA": 5.495780144978007, "OLANZAPINE": 10.31844370654529, "null": 1.6906141848752116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9976.json
new file mode 100644
index 00000000000..a9847b98933
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9976.json
@@ -0,0 +1 @@
+{"ABACAVIR": 0.3695401247550576, "ABILIFY": 17.881137443856215, "ACLIDINIUM": 17.783332048865734, "ADALIMUMAB": 0.0420417442139226, "AERIUS": 2.1648167481074534, "AMINOSALICYLIC": 3.278958317852486, "ANORO": 1.1249974730079133, "APIDRA": 0.45530181615937, "APTIVUS": 9.227838194335083, "ARAVA": 0.0308280039509625, "ARIPIPRAZOLE": 16.5266115426672, "ATAZANAVIR": 41.68580595207388, "ATRIPLA": 0.1499848986830242, "BEDAQUILINE": 5.280063674277921, "BENLYSTA": 0.4247293130396396, "BETAFERON": 1.8573898352554823, "BIKTARVY": 0.783813040860487, "BRINTELLIX": 1.3672487427438953, "BRIVARACETAM": 3.146909279314742, "BRIVIACT": 13.540948584665262, "BUDESONIDE": 0.1469118349134673, "BUMETANIDE": 5.855314795899114, "BUPRENORPHINE": 2.161882248396548, "CANAGLIFLOZIN": 15.998741263512816, "CANNABIDIOL": 8.818956485500166, "CARBIDOPA": 9.270262220614828, "CELLCEPT": 0.4131919455902461, "CHAMPIX": 13.42769021943612, "COMIRNATY": 0.0460114250986065, "COMTAN": 4.474774417384658, "CYMBALTA": 1.838711702538408, "DAKLINZA": 4.714687668640631, "DELAMANID": 2.834763831293116, "DEXAMETHASONE": 0.4729827936881535, "DULOXETINE": 1.4300315818720115, "ELIQUIS": 0.0761839812209982, "ENFUVIRTIDE": 21.41372563484233, "EPCLUSA": 2.4212661204007366, "FAMPYRA": 0.786968995873724, "FENTANYL": 1.1646331673810586, "FYCOMPA": 16.435413817933814, "GARDASIL": 0.56846262714123, "HARVONI": 1.5621183661307525, "IBUPROFEN": 0.2772986334293657, "INCIVO": 0.7857819486068136, "INTRONA": 2.4154655399077165, "INVEGA": 8.494303453081656, "KAFTRIO": 0.7924983884804507, "KALETRA": 1.0220569666184731, "KEPPRA": 8.428271684685235, "LACOSAMIDE": 3.3460934829432505, "LATUDA": 10.779290717492495, "LEVETIRACETAM": 6.390337489606312, "LEVODOPA": 10.037793525066412, "LEVOFLOXACIN": 1.1536668220468944, "LURASIDONE": 8.879112032409159, "LYRICA": 0.4935849931036678, "MICARDIS": 0.7906594982150028, "MIDAZOLAM": 1.1845517592640806, "NEXAVAR": 0.1497276659608558, "NOT": 1.6323099043432352, "OLANZAPINE": 10.875078310885485, "OLYSIO": 1.626944998189776, "OXYBUTYNIN": 4.930518849582636, "PANTOPRAZOLE": 1.0052631863072945, "PEGASYS": 4.165478632477139, "PEGINTERFERON": 3.820405327661158, "PEGINTRON": 4.740014972610066, "PLAVIX": 0.1219989102205845, "REAGILA": 11.141630954124706, "REBETOL": 3.749073537722911, "RIBAVIRIN": 3.5022921063778685, "RISPERIDONE": 8.139262409338215, "SIFROL": 4.195641263478115, "SOLIRIS": 0.2608036198887027, "SPIKEVAX": 0.0567266794691835, "STALEVO": 4.340717643291604, "STELARA": 0.3014468349211958, "SUBOXONE": 2.4895023808653653, "TAMIFLU": 3.7222431832637297, "TIVICAY": 2.9926273487737465, "TOZINAMERAN": 0.1857343959280299, "TRIUMEQ": 3.3703636962415144, "TRUVADA": 0.0771144925499488, "VALSARTAN": 2.052873492381321, "VARENICLINE": 8.623899064165924, "VAXZEVRIA": 0.0502617293879357, "VFEND": 1.935437845458819, "VIAGRA": 0.3475941811975826, "VIGABATRIN": 8.19166123294794, "VIMPAT": 5.068324218192024, "XEPLION": 20.386707798002, "XTANDI": 0.2894377161927907, "XYREM": 5.2358790165350255, "ZONISAMIDE": 7.525407504306917, "ZYPADHERA": 6.155587087679568, "ZYPREXA": 8.378843721672734, "null": 1.819434564523274}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9977.json
new file mode 100644
index 00000000000..4527b440ec5
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9977.json
@@ -0,0 +1 @@
+{"null": 0.6517442293218042}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9978.json
new file mode 100644
index 00000000000..f050e399224
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9978.json
@@ -0,0 +1 @@
+{"ABILIFY": 32.82079170847895, "ARIPIPRAZOLE": 45.82450571885816, "KEPPRA": 2.80944598492746, "LATUDA": 37.1786391081467, "LURASIDONE": 221.79228294144903, "OLANZAPINE": 39.66475575788226, "SUBOXONE": 5.134542508350255, "null": 0.9913573040356084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9979.json
new file mode 100644
index 00000000000..daf7975d7ad
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9979.json
@@ -0,0 +1 @@
+{"null": 1.6210800635805371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/998.json
index d67a8cae467..851600929ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/998.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/998.json
@@ -1 +1 @@
-{"null": 1.070213856071489}
\ No newline at end of file
+{"SKYRIZI": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9980.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9980.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9981.json
new file mode 100644
index 00000000000..070fa6502f9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9981.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.2927184009471464, "null": 0.3357036215565476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9982.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9982.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9983.json
new file mode 100644
index 00000000000..822cb341ebd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9983.json
@@ -0,0 +1 @@
+{"COMIRNATY": 1.1969894723546444, "null": 1.181174239710313}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9984.json
new file mode 100644
index 00000000000..dbe5aa40fb7
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9984.json
@@ -0,0 +1 @@
+{"COMIRNATY": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9985.json
new file mode 100644
index 00000000000..83a0b042201
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9985.json
@@ -0,0 +1 @@
+{"null": 0.7935073517165068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9986.json
new file mode 100644
index 00000000000..b30aabc7826
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9986.json
@@ -0,0 +1 @@
+{"ADCIRCA": 7.579080276744194, "ALEMTUZUMAB": 6.161411891175391, "ANORO": 150.9443917057108, "APIXABAN": 24.01674833110748, "AZATHIOPRINE": 11.909114882528094, "BUSULFAN": 10.699623431443188, "CANCIDAS": 7.533468878919313, "CEFUROXIME": 50.65044261465893, "CELLCEPT": 3.917607016456537, "CICLOSPORIN": 2.714221649880832, "CLOPIDOGREL": 7.8377983299823635, "COMIRNATY": 0.0903994662340581, "CYTARABINE": 2.0754669119067217, "DEFITELIO": 106.68041045205912, "DEXAMETHASONE": 1.1936861843155335, "EFIENT": 61.38074092182914, "ELIQUIS": 7.38926120452117, "ENOXAPARIN": 5.426935522074787, "EPTIFIBATIDE": 105.89690505423144, "FENTANYL": 1.304842275998631, "INTEGRILIN": 36.71392107007821, "IRESSA": 5.783167906744686, "JAKAVI": 2.982980934284573, "KEYTRUDA": 0.6887243367572855, "LEMTRADA": 4.6561172992204565, "LEVOFLOXACIN": 1.6073868712003554, "NEXAVAR": 1.004832794397346, "OPSUMIT": 3.1554667951821656, "PLAVIX": 3.402200048721525, "RITUXIMAB": 1.8787355704364677, "SOLIRIS": 1.7502785715844065, "SPIKEVAX": 0.0504235912404714, "SPRYCEL": 2.1635207220795505, "TAGRISSO": 4.041715289510191, "TICAGRELOR": 14.28467889812784, "TRACLEER": 1.5952230592904575, "XARELTO": 9.978223399768538, "null": 0.9370534854674089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9987.json
new file mode 100644
index 00000000000..aa01bf44fdf
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9987.json
@@ -0,0 +1 @@
+{"ADEMPAS": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9988.json
new file mode 100644
index 00000000000..030666f2ec4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9988.json
@@ -0,0 +1 @@
+{"null": 1.089571437511803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9989.json
new file mode 100644
index 00000000000..b18889cd8bb
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9989.json
@@ -0,0 +1 @@
+{"ABILIFY": 0.6370082548711578, "ADCIRCA": 34.03274727586867, "ADEMPAS": 42.91335308582476, "AMBRISENTAN": 31.80249356509378, "APROVEL": 4.593257087603842, "ARAVA": 0.2380087408652277, "AVANDIA": 0.7878391169249155, "BEDAQUILINE": 7.800259158453333, "BOSENTAN": 56.80937364260403, "BOSULIF": 15.220031608803955, "BOSUTINIB": 14.128533477436848, "BUSULFAN": 4.645262541654477, "CARFILZOMIB": 5.583655652710875, "CICLOSPORIN": 0.4100922981269607, "COMIRNATY": 0.0242618547033085, "DACLATASVIR": 14.949931443156368, "DAKLINZA": 13.100647152090543, "DEXAMETHASONE": 0.6931891097234285, "ELIQUIS": 0.731115297964084, "ESBRIET": 2.013727135491629, "HARVONI": 2.038853115278949, "ICLUSIG": 2.6699524652904234, "ILOPROST": 133.50185266869389, "INSULIN": 2.66700584992565, "JAKAVI": 2.561714910035653, "KYPROLIS": 8.058510628485982, "LYRICA": 1.371162140946537, "MACITENTAN": 94.08349336414987, "METHOTREXATE": 0.8832107814959865, "NILOTINIB": 6.028320894887822, "NOXAFIL": 5.0337067460999245, "OFEV": 3.181696056288685, "OPSUMIT": 140.51353714803545, "PEGASYS": 1.2919086556317614, "PEGINTERFERON": 1.114550331864402, "REBETOL": 4.08549793623459, "REVATIO": 21.9022734796344, "RIBAVIRIN": 2.3689584657338605, "SILDENAFIL": 35.886569843965944, "SPRYCEL": 29.83150528206673, "SUTENT": 0.1583138063706658, "TASIGNA": 1.1694656656524285, "THIOTEPA": 17.042966491558634, "TRACLEER": 140.41012890439302, "UPTRAVI": 52.81603703721336, "null": 0.5484261591475519}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/999.json
index 23684885fae..80f256a24b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/999.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/999.json
@@ -1 +1 @@
-{"ADENURIC": 53.82988560392123, "AFINITOR": 7.802715664683691, "JAKAVI": 9.85098635497116, "KEYTRUDA": 3.345762585899509, "NEXAVAR": 4.833402952007588, "OCALIVA": 88.7207386379766, "OLYSIO": 54.23594779242484, "SOLIRIS": 12.210732089417172, "SUTENT": 3.538830123282134}
\ No newline at end of file
+{"null": 2.0329871054297275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9990.json
new file mode 100644
index 00000000000..5f1a3e351ce
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9990.json
@@ -0,0 +1 @@
+{"IRBESARTAN": 167.3149328719622, "OPSUMIT": 43.98731657451353, "null": 0.6819504044407018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9991.json
new file mode 100644
index 00000000000..3982c4303f4
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9991.json
@@ -0,0 +1 @@
+{"null": 0.6842411932383017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9992.json
new file mode 100644
index 00000000000..0a3c554b303
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9992.json
@@ -0,0 +1 @@
+{"ENALAPRIL": 244.09730022711895, "OPSUMIT": 71.28513139714747, "REVATIO": 53.59038141320446, "SILDENAFIL": 50.29454400773064, "TRACLEER": 34.96529188329854, "null": 1.014894245477288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9993.json
new file mode 100644
index 00000000000..d15d524327a
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9993.json
@@ -0,0 +1 @@
+{"null": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9994.json
new file mode 100644
index 00000000000..6ed6d3e8c0b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9994.json
@@ -0,0 +1 @@
+{"OPSUMIT": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9995.json
new file mode 100644
index 00000000000..2ea49612713
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9995.json
@@ -0,0 +1 @@
+{"OPSUMIT": 88.2581423878588, "null": 1.213142761852697}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9996.json
new file mode 100644
index 00000000000..f0401afe8dc
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9996.json
@@ -0,0 +1 @@
+{"null": 0.5234282361212452}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9997.json
new file mode 100644
index 00000000000..c937886b366
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9997.json
@@ -0,0 +1 @@
+{"null": 2.331557647827097}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9998.json
new file mode 100644
index 00000000000..e53811c2c74
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9998.json
@@ -0,0 +1 @@
+{"OPSUMIT": 34.98434995713723, "null": 0.8569414768866037}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9999.json
new file mode 100644
index 00000000000..8669278819f
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/symptoms/9999.json
@@ -0,0 +1 @@
+{"SPIRONOLACTONE": null}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1.json
index ab2b414cec2..3ae3ddd5f2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1.json
@@ -1 +1 @@
-{"Constipation ": 17.649962607021507, "Dyspnoea ": 3.549147030514927, "Flatulence ": 77.6903463799255, "Oropharyngeal pain ": 23.775160354588635, "Stevens-Johnson syndrome ": 67.16782399335501, "Toxic epidermal necrolysis ": 102.8388320701753}
\ No newline at end of file
+{"Constipation": 17.649962607021507, "Dyspnoea": 3.5490943061549447, "Flatulence": 77.68403086713583, "Oropharyngeal pain": 23.775160354588635, "Stevens-Johnson syndrome": 67.16782399335501, "Toxic epidermal necrolysis": 102.8388320701753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/10.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/10.json
index 5f3dcce0e3c..01c346e2669 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/10.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/10.json
@@ -1 +1 @@
-{"Anaemia ": 3.221139019553731, "Ascites ": 10.14915246132696, "Bone disorder ": 10.893484085997594, "Breast cancer ": 12.773341168622522, "Breast cancer metastatic ": 138.3994817997619, "Burning sensation ": 2.8588241058322024, "Cellulitis ": 2.494823195421424, "Cholangitis ": 15.685979048365702, "Colitis ": 3.2960868771241767, "Cytogenetic analysis abnormal ": 137.05939990758466, "Dehydration ": 2.809936588812284, "Disease progression ": 5.21830205447912, "Drug-induced liver injury ": 2.0043875657427934, "Dyspnoea exertional ": 3.8190710535249415, "Enterocolitis ": 11.859604200114305, "Febrile neutropenia ": 11.1327560184904, "Gene mutation ": 91.3961623391678, "Hepatic lesion ": 55.30702437836333, "Hypophagia ": 23.78003164441682, "Hypoxia ": 2.816162523260792, "Immune-mediated enterocolitis ": 17.59032851999298, "Interstitial lung disease ": 10.92154847537796, "Joint stiffness ": 8.050645948755175, "Liver disorder ": 2.642989716356119, "Malignant neoplasm progression ": 23.199986162423457, "Metastases to bone ": 67.35189139787303, "Metastases to central nervous system ": 13.197444504172031, "Metastases to liver ": 33.89317051002639, "Metastases to lung ": 27.63412771485676, "Metastases to pelvis ": 264.92328007524685, "Metastases to peritoneum ": 49.41912303055205, "Metastases to skin ": 81.71431836821557, "Metastasis ": 30.71685088447018, "Mouth ulceration ": 9.370436500008594, "Mucosal inflammation ": 4.013792314933522, "Myelosuppression ": 5.778864293248316, "Nail avulsion ": 1241.19955539701, "Neoplasm progression ": 12.139220611551323, "Neuropathy peripheral ": 8.785271456498513, "Neutropenia ": 3.59197947071274, "Neutrophil count decreased ": 3.848992886754123, "PIK3CA-activated mutation ": 384.2762242630757, "Palmar-plantar erythrodysaesthesia syndrome ": 3.692960490420063, "Pancreatic carcinoma ": 3.9089567940666585, "Pancreatic carcinoma metastatic ": 22.55899605603173, "Peripheral sensory neuropathy ": 14.671557522902848, "Pleural effusion ": 8.437691917801445, "Pneumonitis ": 10.89664039951243, "Pulmonary mass ": 23.2670822950978, "Skin disorder ": 2.1930768722299785, "Spinal compression fracture ": 11.192615021638726, "Staphylococcal infection ": 5.857026410008794, "Stomatitis ": 5.317968489156255, "Thrombocytopenia ": 2.46024335371934, "Tumour marker increased ": 50.55661377691028, "White blood cell count decreased ": 2.5571074605085102}
\ No newline at end of file
+{"Emotional distress": 161.85208465362794, "Hypersensitivity": 70.04082379006084, "Injury": 405.2825412437928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/100.json
index 4a73f3009f6..765f81c07f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/100.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 3.5800787348313428, "Abdominal pain upper ": 2.786301084984288, "Acquired factor V deficiency ": 325.4498570287546, "Adverse drug reaction ": 4.124214503198084, "Adverse event ": 8.715683942305368, "Alopecia ": 2.4631195164543724, "Amnesia ": 7.154508936557738, "Angioedema ": 3.885427177458935, "Anosmia ": 19.613382525324305, "Antineutrophil cytoplasmic antibody positive ": 120.94204205228588, "Anxiety ": 2.6870004242757988, "Aortic valve stenosis ": 88.8763762670528, "Arteriosclerosis ": 13.01060907744372, "Arteriosclerosis coronary artery ": 21.80719611464464, "Asthma ": 10.779404910037432, "Atelectasis ": 2.880160341967985, "Atrial fibrillation ": 5.460043157999593, "Atrial tachycardia ": 196.8941164544109, "Atrial thrombosis ": 11.374088001647412, "Atrioventricular block first degree ": 2.7007338246227097, "Benign prostatic hyperplasia ": 22.964492168309945, "Blindness ": 10.909800337939425, "Blood glucose increased ": 2.4294750016068587, "Blood pressure diastolic decreased ": 3.984090147810893, "Blood pressure diastolic increased ": 2.3442386051793638, "Blood test abnormal ": 79.42991019491899, "Body height decreased ": 2.2767805034840185, "Bronchial secretion retention ": 87.76396177459479, "Bronchial wall thickening ": 96.09142190130868, "Bronchiectasis ": 17.766061986784205, "Bronchopulmonary aspergillosis allergic ": 26.04438636805492, "Burning sensation ": 13.452815762813104, "Cardiac amyloidosis ": 14.046934404415005, "Cardiac disorder ": 11.77491962924847, "Cardiac failure chronic ": 3.5522191955200424, "Cardiac failure congestive ": 2.685448509104165, "Cardiospasm ": 1755.0608311671162, "Carotid artery occlusion ": 144.15541599236258, "Carpal tunnel syndrome ": 96.6988922946502, "Cerebral thrombosis ": 3.715959814813084, "Chest X-ray abnormal ": 19.449427688773334, "Chronic sinusitis ": 2.6851397387148657, "Coagulation factor V level abnormal ": 225.2066524907245, "Coagulation factor deficiency ": 140.54875677027138, "Cognitive disorder ": 10.548922457421796, "Congenital anomaly ": 4.782000810796671, "Conjunctivitis allergic ": 79.75215614792687, "Defaecation disorder ": 9.745787080363831, "Dehydration ": 4.10433782734644, "Diastolic dysfunction ": 38.52193672126027, "Dilated cardiomyopathy ": 4.500407327742218, "Diplopia ": 14.309936315100297, "Disturbance in attention ": 4.915530056991187, "Dry skin ": 12.245289559497731, "Dust allergy ": 116.63243306983888, "Dyspnoea ": 2.6565508940948543, "Dyspnoea exertional ": 6.65119772559568, "Ear congestion ": 9.488474184970617, "Ejection fraction ": 1042.0477678571517, "Ejection fraction abnormal ": 241.24298645012647, "Ejection fraction decreased ": 2.4558304065227428, "Eosinophilic granulomatosis with polyangiitis ": 24.45881786595038, "Eye pruritus ": 22.50893823645626, "Facial pain ": 32.94053687440106, "Factor V Leiden mutation ": 42.85369962587031, "Feeling abnormal ": 2.51854014652162, "Fibromyalgia ": 30.23298987729095, "Forced expiratory volume decreased ": 45.11370910207286, "Full blood count abnormal ": 23.974572012323087, "Gastrooesophageal reflux disease ": 14.901966211884067, "Gout ": 7.353852795158407, "Haemoptysis ": 6.17746490803406, "Haemorrhage intracranial ": 2.0143098112869464, "Hallucination ": 4.222756005850279, "Heart rate increased ": 3.370085165709133, "Hepatic lesion ": 6.406212220377328, "Hospitalisation ": 5.455143186157754, "Human rhinovirus test positive ": 65.87291187423753, "Hypertension ": 3.948890184146317, "Hypoacusis ": 3.351723965112884, "Hypothyroidism ": 18.169311126462624, "Hypoxia ": 5.007494141037422, "Immunisation ": 2.832845719534628, "Infective exacerbation of chronic obstructive airways disease ": 232.84937188389412, "Infusion site erythema ": 2.6525611591279143, "Insomnia ": 2.553126197783168, "Intentional product misuse ": 3.2768825125569387, "Intentional product use issue ": 6.589281735569899, "Intervertebral disc degeneration ": 14.593461593957606, "Kyphosis ": 6.105948595034922, "Labelled drug-drug interaction medication error ": 3.0717015409436903, "Left atrial dilatation ": 6.734445334771607, "Ligament sprain ": 3.8886672281490826, "Lip swelling ": 7.409324600881119, "Loss of personal independence in daily activities ": 17.268819031060907, "Low cardiac output syndrome ": 27.79362773157298, "Lower gastrointestinal haemorrhage ": 2.7156074591696804, "Lung consolidation ": 11.503877413520607, "Lung disorder ": 3.864715787336343, "Memory impairment ": 3.247522042183846, "Migraine ": 2.2236352577719205, "Mite allergy ": 136.10388769069826, "Mitral valve incompetence ": 2.9908560542017755, "Mouth haemorrhage ": 3.091924044141797, "Multiple allergies ": 10.967333982460408, "Muscle twitching ": 6.9691791912211976, "Mycobacterial infection ": 17.74908051016117, "Mycotic allergy ": 146.55802373300943, "N-terminal prohormone brain natriuretic peptide increased ": 5.526574847574149, "Nephrectomy ": 153.57676362043054, "Nephropathy ": 12.189822269918857, "Neuritis ": 39.321051932693294, "Neurological symptom ": 19.34594258814763, "Nodule ": 14.55260144657266, "Normochromic normocytic anaemia ": 63.48623105771417, "Obesity ": 18.26453764316842, "Obstruction ": 58.36573228558085, "Obstructive airways disorder ": 17.47786672280041, "Obstructive sleep apnoea syndrome ": 81.21641842899147, "Onychoclasis ": 2.508279712699573, "Oropharyngeal pain ": 2.1477382345962184, "Orthopnoea ": 4.7469339140936135, "Pain of skin ": 3.966077238203885, "Palmoplantar keratoderma ": 89.21134541175363, "Pericardial haemorrhage ": 10.342562057030207, "Polycystic ovarian syndrome ": 25.993378412514986, "Polycystic ovaries ": 996.103608613361, "Procedural haemorrhage ": 2.671425100550385, "Productive cough ": 7.078654324062947, "Pruritus genital ": 8.592697110992848, "Pulmonary alveolar haemorrhage ": 25.446519638449697, "Pulmonary embolism ": 2.0682946432637017, "Pulmonary fibrosis ": 7.385625998221702, "Pulmonary function test abnormal ": 24.79396357922719, "Pulmonary 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2.9013963773802973, "Therapeutic product effect incomplete ": 11.847295744364002, "Troponin T increased ": 4.984985173486977, "Vascular pseudoaneurysm ": 5.146011090566589, "Vasculitis ": 2.630909178957729, "Ventricular arrhythmia ": 4.410217816326856, "Ventricular tachycardia ": 2.82057731676507, "Wheezing ": 13.498227550798324, "Wound haemorrhage ": 2.842972186660113}
\ No newline at end of file
+{"Hormone-refractory prostate cancer": 357.33944216139383, "Malignant neoplasm progression": 5.112240598587916, "Prostate cancer metastatic": 383.29016688632737, "Prostatic specific antigen increased": 97.51335005611386, "Rash": 5.3216711927156535}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1000.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1000.json
index ffbba2d4422..a94da3309b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1000.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1000.json
@@ -1 +1 @@
-{"Acromegaly ": 1167.8586757180838, "Arterial occlusive disease ": 61.40886252165932, "Blood cholesterol abnormal ": 125.68558345530217, "Blood growth hormone increased ": 1567.6136640463608, "Blood pressure increased ": 2.686796936401434, "Bradycardia ": 8.070583443582892, "Cellulitis ": 10.484020847367836, "Chest discomfort ": 3.042157678075463, "Drug hypersensitivity ": 6.223032204913022, "Drug intolerance ": 7.66977011149899, "Fall ": 2.486091072955514, "Gait disturbance ": 3.1426323205125577, "Goitre ": 97.82226335142823, "Heart rate decreased ": 15.84040714212818, "Hypersensitivity ": 4.052739252482582, "Inappropriate schedule of product administration ": 7.913379590326489, "Incorrect route of product administration ": 16.851669547281585, "Injection site bruising ": 42.68564604487056, "Injection site oedema ": 48.46273341790186, "Injection site pain ": 2.163059552454616, "Insulin-like growth factor increased ": 2152.5677485815067, "Limb injury ": 28.849978134739857, "Peripheral swelling ": 2.480743531082287, "Polyp ": 126.81002671235574, "Pulmonary embolism ": 5.5440660845432586, "Syringe issue ": 158.79809861795198, "Tendonitis ": 21.905398881491408, "Vital functions abnormal ": 721.8178136516517, "Weight decreased ": 2.1154762204860043, "Wound infection ": 82.84083206435105}
\ No newline at end of file
+{"Abdominal abscess": 2.708885514326054, "Abnormal loss of weight": 2.03435866918208, "Abscess": 6.347094702928869, "Abscess limb": 6.581368394862498, "Abscess oral": 8.93857092349803, "Accident": 3.279193546125703, "Accidental exposure to product": 35.529132067159274, "Accidental underdose": 3.559825703419031, "Adenocarcinoma of colon": 4.224459404729405, "Administration site bruise": 12.777262155198896, "Administration site infection": 394.6043190142624, "Adverse drug reaction": 2.1045104928881324, "Adverse event": 2.8176810210453724, "Alopecia areata": 2.346365668064892, "Amyotrophic lateral sclerosis": 2.791571518521819, "Anal abscess": 4.160748136818152, "Anal fistula": 5.595216454595147, "Ankylosing spondylitis": 53.87304493530668, "Application site discolouration": 4.764251202101868, "Application site haemorrhage": 11.47787761453078, "Arthritis": 5.309385647707847, "Arthritis bacterial": 9.186060613551158, "Arthritis infective": 7.436339310365863, "Arthropod bite": 4.812431365779908, "Atypical mycobacterial infection": 9.338197386498036, "Atypical pneumonia": 2.0899023310397293, "Axial spondyloarthritis": 19.78909575832424, "B-cell lymphoma": 3.2690335574545224, "Basal cell carcinoma": 3.692580778016973, "Bedridden": 3.3756721305802397, "Blood test abnormal": 3.843730544139679, "Body height decreased": 2.6014124389925875, "Breast cancer": 2.4639818754248943, "Bronchitis": 3.158091645401281, "Calculus urinary": 2.564949500129336, "Cardiac operation": 2.5649185066642874, "Carpal tunnel syndrome": 3.7606608607684446, "Cataract": 2.621181411870292, "Catarrh": 3.118958443952325, "Cellulitis": 5.3438987518508, "Cervix carcinoma": 2.7778310382755245, "Chemotherapy": 8.171946463991162, "Chikungunya virus infection": 24.422793006227327, "Cholecystectomy": 2.8810418969989877, "Chondropathy": 6.799798958327733, "Chronic lymphocytic leukaemia": 2.017092360891646, "Clear cell renal cell carcinoma": 4.922833260655205, "Colectomy": 11.078825352381264, "Colitis ulcerative": 23.719875874466226, "Colon cancer": 3.346514946640281, "Complication associated with device": 7.700278955182457, "Contraindication to vaccination": 18.75651802753144, "Coronavirus infection": 5.7565194817689, "Crohn's disease": 4.200038313002567, "Cutaneous T-cell lymphoma": 3.8919490181914447, "Cutaneous vasculitis": 4.107385103605791, "Cyst": 2.8726562054053923, "Cystitis": 2.1291264810773787, "Decreased immune responsiveness": 7.971752282537459, "Demyelinating polyneuropathy": 3.4090317937624186, "Demyelination": 18.98522548038488, "Dengue fever": 37.64142926552065, "Dental care": 29.93283878694057, "Dental operation": 20.70251882170237, "Dermatitis psoriasiform": 12.319920637487035, "Device defective": 15.68306414615475, "Device delivery system issue": 2.190513351021554, "Device deployment issue": 225.04004545805984, "Device failure": 4.061746368499207, "Device infusion issue": 6.01650973874846, "Device issue": 17.45568090724596, "Device leakage": 17.052844383176964, "Device malfunction": 11.005562053160387, "Device occlusion": 4.421954000028527, "Device related infection": 3.2504947018307058, "Device use issue": 6.14041394171742, "Diarrhoea haemorrhagic": 3.979523135283906, "Disseminated tuberculosis": 16.75209938013815, "Diverticulitis": 3.9339476961592954, "Drug delivery system issue": 9.252499300849657, "Drug delivery system malfunction": 287.08708841068693, "Drug ineffective": 2.613128979786977, "Ear infection": 8.883791233118792, "Emphysema": 2.0984131112964737, "Endocarditis": 2.3135143467766723, "Endodontic procedure": 9.25724806296796, "Enthesopathy": 3.2508450508298554, "Eosinophilic pneumonia": 2.089514630422693, "Erysipelas": 5.106090008113961, "Exostosis": 3.624010368856305, "Exposure via skin contact": 8.896615825179344, "Eye infection": 7.01156122951659, "Eye operation": 7.681805732137042, "Faecal calprotectin increased": 4.649867709614697, "Felty's syndrome": 72.91188094610021, "Femur fracture": 2.974252636318644, "Finger deformity": 2.0534771549350617, "Fistula": 3.343145974005516, "Flavivirus infection": 203.5747351817641, "Food poisoning": 3.5604538045095167, "Foot deformity": 3.2204537318002884, "Foot operation": 18.29962574799945, "Frequent bowel movements": 2.1545851650890784, "Furuncle": 5.271877572437044, "Gallbladder operation": 12.6262384910705, "Gastric infection": 4.354706927023201, "Gastrointestinal carcinoma": 2.129365450296284, "Gastrointestinal infection": 3.4691956295235644, "Gastrointestinal inflammation": 2.1758300744304524, "General physical condition abnormal": 4.180621706128001, "Genital herpes": 2.1431170333354466, "Gingival abscess": 14.519827635965832, "Gingivitis": 2.523489823763614, "Glomerulonephritis": 4.571076360576318, "Glomerulonephritis rapidly progressive": 6.4786283952236605, "Groin abscess": 9.825500938587751, "Heart valve replacement": 9.255261727526465, "Hepatitis B": 2.783373511160178, "Hernia": 5.854400237779444, "Herpes virus infection": 6.5030429676225, "Hip 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tuberculosis": 9.897086756637323, "Ligament rupture": 2.763089859886355, "Ligament sprain": 2.274015410167851, "Limb mass": 7.874345015141874, "Limb operation": 23.238197067909848, "Localised infection": 7.5015166914734435, "Loss of therapeutic response": 19.728019018088546, "Lower limb fracture": 3.496884685082009, "Lower respiratory tract infection": 31.367890146220507, "Lung adenocarcinoma": 6.313266472185103, "Lung neoplasm malignant": 2.168795526601157, "Lupus nephritis": 7.727969652014015, "Lupus-like syndrome": 12.769318017320208, "Lyme disease": 2.127427535831008, "Lymph node tuberculosis": 19.494614275816797, "Lymphocytosis": 3.187009380286599, "Lymphoma": 4.330612911805459, "Lymphoproliferative disorder": 5.892250758677986, "Malignant melanoma": 4.123749254333951, "Marasmus": 7.2458069357004415, "Mass": 2.822972695648324, "Medical device implantation": 12.883539110799138, "Melanocytic naevus": 5.802748229277251, "Meniscus injury": 3.195123604768693, "Metabolic surgery": 9.652839627506966, "Mucous stools": 3.042904488620355, "Multiple sclerosis": 4.117131880928898, "Mycobacterium tuberculosis complex test positive": 17.59574906046521, "Myelitis": 2.917147459895616, "Nasopharyngitis": 6.051890770944383, "Neck mass": 3.120824705035026, "Neck surgery": 6.9722765468112, "Needle issue": 30.7605341671301, "Neoplasm": 4.084357883263987, "Neoplasm malignant": 2.2495269826113806, "Nephrolithiasis": 2.570885487295845, "Nerve compression": 2.408333567435322, "Off label use": 3.407244155276438, "Optic neuritis": 2.933663818050624, "Oral fungal infection": 2.339390974892345, "Oral herpes": 3.4612731365721494, "Oral infection": 7.15911562746266, "Organising pneumonia": 3.6275679526940032, "Osteitis": 5.137381987516688, "Osteoarthritis": 2.916287537347727, "Osteomyelitis": 5.515745175652604, "Ovarian cancer": 2.202566474507341, "Ovarian cyst": 2.2468844852654364, "Palmoplantar pustulosis": 43.70860451007567, "Papillary thyroid cancer": 4.136550145026031, "Papilloma viral infection": 4.77743216925028, "Paradoxical drug reaction": 4.524261988290436, "Paternal exposure during pregnancy": 13.391951093347028, "Periodontitis": 3.29068090757372, "Peritoneal tuberculosis": 41.59698921073479, "Pharyngitis": 13.121279774519005, "Pleurisy": 3.825345506352041, "Pneumocystis jirovecii pneumonia": 7.1019196961787605, "Pneumonia": 3.396903010141789, "Pneumonia bacterial": 5.371408889403349, "Pneumonia legionella": 8.575987738904857, "Polyarthritis": 2.7915290497234566, "Poor quality product administered": 6.061300373597041, "Post procedural complication": 2.144096932131036, "Post procedural infection": 12.19361889626844, "Postoperative wound infection": 3.948586793942425, "Product availability issue": 3.237748449222335, "Product dose omission issue": 26.74210323178228, "Product label issue": 5.474097044557135, "Product leakage": 4.408432270846336, "Product packaging issue": 5.038172966740743, "Product packaging quantity issue": 5.658606641082699, "Product 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"Sarcoidosis": 5.992100404854211, "Scleritis": 7.201748581646821, "Seasonal allergy": 2.2592287120582357, "Sepsis": 2.0676172207288688, "Serum ferritin decreased": 3.4778267499864217, "Shoulder arthroplasty": 7.874250786514022, "Shoulder operation": 14.50434041766916, "Sinusitis": 3.247646004490337, "Sjogren's syndrome": 3.9645740979245336, "Skin cancer": 4.78025856512243, "Skin fissures": 2.0447694318975693, "Skin infection": 6.172888397911713, "Skin ulcer": 2.0059941432518245, "Spinal compression fracture": 3.057857714453219, "Spinal disorder": 3.190517815821006, "Spinal fracture": 2.866677624461205, "Spinal operation": 8.213652266177053, "Spinal pain": 2.084665980689273, "Spondylitis": 12.132794992537834, "Staphylococcal infection": 2.131760812282028, "Subcutaneous abscess": 5.851243638801417, "Surgery": 16.480223027735956, "Synovial cyst": 3.769085851871375, "Syphilis": 8.443390340947678, "Syringe issue": 22.933730773841766, "Testis cancer": 2.2837632330912627, "Therapeutic product effect decreased": 3.998414089879866, "Therapeutic product ineffective": 4.6929580207452375, "Therapeutic response decreased": 5.762320150730029, "Therapeutic response shortened": 2.6618177746257925, "Therapy cessation": 3.207950368446388, "Thyroid cancer": 2.6258129615008894, "Toe operation": 22.79091043231759, "Tonsillitis": 12.516488808160586, "Tooth abscess": 14.52092566594615, "Tooth extraction": 14.06304086346126, "Tooth infection": 11.570686992183516, "Trigger finger": 3.36580688381273, "Tuberculin test positive": 8.508604334909261, "Tuberculosis": 12.65540919227754, "Tuberculous pleurisy": 36.93286330474748, "Tympanic membrane perforation": 5.250037202821727, "Underdose": 12.760174510306848, "Upper limb fracture": 3.051808492820276, "Urinary tract infection": 5.253850402274498, "Urinary tract infection bacterial": 3.539460010100079, "Urticarial vasculitis": 4.786117018636375, "Uterine cancer": 3.022634013855576, "Uterine leiomyoma": 4.042486266589252, "Uveitis": 8.091165755975192, "Vaginal infection": 3.350090473310112, "Varicose vein": 3.562863147155736, "Vasculitis": 2.286873101973788, "Viral infection": 8.30195496506259, "Volvulus": 5.008760430623346, "Weight fluctuation": 2.0069245222155248, "Wisdom teeth removal": 25.182102751763047, "Wound complication": 4.238256399017906, "Wound infection": 2.471649819295023, "Wrist surgery": 13.53340281014781}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1001.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1001.json
index 5251693d2a7..1e789068a2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1001.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1001.json
@@ -1 +1 @@
-{"Intentional overdose ": 36.05160301566608}
\ No newline at end of file
+{"Blood creatinine increased": 10.554728842142492, "Kidney transplant rejection": 453.1409148085539}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1002.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1002.json
index 96de75b2383..d1596c8365e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1002.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1002.json
@@ -1 +1 @@
-{"Alpha 1 foetoprotein increased ": 117.58745308698218, "Ascites ": 5.550053398271658, "Blister ": 3.4120996548188627, "Diarrhoea ": 3.340768320133641, "Disease progression ": 5.839117538334553, "Drug ineffective for unapproved indication ": 6.258355117317848, "Erythema multiforme ": 5.510979238909851, "Haematotoxicity ": 11.741519357162655, "Hepatic encephalopathy ": 10.293247755647284, "Hepatic failure ": 6.0591430036270655, "Hepatocellular carcinoma ": 45.14421136202953, "Hepatotoxicity ": 5.478867204588851, "Hyperkeratosis ": 18.3733643542266, "Hypertension ": 3.0134384879071807, "Hypocalcaemia ": 9.6470695970997, "International normalised ratio increased ": 2.1038195462158686, "Malignant neoplasm progression ": 2.809789132493224, "Metastases to adrenals ": 69.905760963194, "Metastases to bone ": 8.459648334480317, "Metastases to liver ": 6.502514645388471, "Metastases to lung ": 30.543054872294285, "Metastatic renal cell carcinoma ": 30.86796027671447, "Mucosal inflammation ": 8.28979992726653, "Neoplasm progression ": 3.452534897166229, "Off label use ": 5.294186295744967, "Osteonecrosis of jaw ": 14.70981260897226, "Palmar-plantar erythrodysaesthesia syndrome ": 71.92652538146406, "Product use in unapproved indication ": 7.835608085660607, "Rash maculo-papular ": 2.776626436271433, "Renal cell carcinoma ": 15.910019249109528, "Skin exfoliation ": 2.8192660283382813, "Skin reaction ": 4.758319618050393, "Skin toxicity ": 49.06436858647975, "Skin ulcer ": 6.50701368486814, "Squamous cell carcinoma of skin ": 28.353003645537928, "Stevens-Johnson syndrome ": 4.156051349482739, "Thrombocytopenia ": 3.7812584689836473, "Tumour lysis syndrome ": 15.731632606322991, "Weight decreased ": 2.306152531961974}
\ No newline at end of file
+{"Acute kidney injury": 3.534002050770199, "Angioedema": 7.539282653142957, "Drug ineffective for unapproved indication": 20.73629511858232, "Drug interaction": 16.028467435603925, "Liver transplant rejection": 340.61135450972023, "Off label use": 3.728950871336153, "Product use in unapproved indication": 8.56891060528179, "Transplant rejection": 68.93462089310147}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1003.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1003.json
index 96d515a1766..36d35a2dcf2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1003.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1003.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 10.805313105473848, "Aspartate aminotransferase increased ": 9.902324177422711, "Blood bilirubin increased ": 9.164748462552684, "Diarrhoea ": 5.963991070516686, "Disease progression ": 10.689063711986478, "Drug-induced liver injury ": 10.625814518937682, "Hepatic enzyme increased ": 5.34836961827246, "Hepatic function abnormal ": 9.268010685628123, "Hepatotoxicity ": 44.974335675532025, "Liver disorder ": 6.937692081216955, "Liver function test increased ": 17.2586945444678, "Lung adenocarcinoma ": 136.47393837646254, "Lung neoplasm malignant ": 12.518128619614066, "Non-small cell lung cancer ": 917.6710243441228, "Non-small cell lung cancer metastatic ": 2736.759079656651, "Off label use ": 2.092753891529357, "Therapy partial responder ": 73.56637711356981}
\ No newline at end of file
+{"Alanine aminotransferase increased": 4.805884049268032, "Anaemia": 3.8919569772032, "Aspartate aminotransferase increased": 4.228994240474632, "Blood potassium decreased": 18.92882110415466, "Death": 2.4279047452921247, "Drug-induced liver injury": 11.672797761891626, "Electrocardiogram QT prolonged": 112.0765038457217, "Haemoglobin decreased": 2.7795116537951228, "Hepatic function abnormal": 4.097208895425196, "Hypokalaemia": 3.030467415493918, "Intentional product use issue": 20.168822450481315, "Liver injury": 12.052242875590746, "Neuropathy peripheral": 7.837996165019741, "Off label use": 5.954478088971817, "Product use issue": 5.170778410045484, "Pulmonary tuberculosis": 70.57367086101097, "Rash pruritic": 3.546455720479756, "Respiratory failure": 11.78429460621224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1004.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1004.json
index c91498f9d19..dbf49a0ed97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1004.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1004.json
@@ -1 +1 @@
-{"Altered state of consciousness ": 2.024050394367631, "Ammonia increased ": 7.394131877404162, "Anaemia ": 8.55958588248953, "Ascites ": 9.094616982559542, "Atrial septal defect ": 6.304609474381127, "Autoimmune hepatitis ": 4.34647692809549, "Blood bilirubin increased ": 7.412695506256812, "Cerebral haemorrhage ": 2.4261612946622457, "Cerebral infarction ": 3.809744463535769, "Colitis ischaemic ": 5.542067546483547, "Death ": 2.0131114079317567, "Depression ": 2.201360839632474, "Disseminated intravascular coagulation ": 2.2543983797041407, "Drug ineffective ": 9.329143511706736, "Genotype drug resistance test positive ": 15.422815593871432, "Glomerular filtration rate decreased ": 4.504709760160125, "Haematemesis ": 3.071148194505439, "Haemoglobin decreased ": 8.082692589051026, "Haemolytic anaemia ": 12.313385417004216, "Hepatic cancer ": 14.629033122198743, "Hepatic cancer recurrent ": 602.0039890255414, "Hepatic cirrhosis ": 22.786745654044303, "Hepatic encephalopathy ": 28.74600624895768, "Hepatic failure ": 5.931417114939051, "Hepatic fibrosis ": 12.041285487330828, "Hepatitis ": 3.55365924842276, "Hepatitis B reactivation ": 24.750836315201404, "Hepatitis C ": 140.67988130454347, "Hepatitis C RNA increased ": 76.9606002229754, "Hepatitis C RNA positive ": 259.072465501785, "Hepatitis C virus test positive ": 55.05430937726681, "Hepatocellular carcinoma ": 48.2368636220552, "Hepatorenal syndrome ": 16.059846038349804, "Hyperbilirubinaemia ": 19.273544181611605, "Incorrect product administration duration ": 6.3377282494176175, "Infection reactivation ": 75.01193638089899, "Jaundice ": 7.378857502671108, "Loss of consciousness ": 2.441487455317065, "Lung neoplasm malignant ": 2.0633085005915626, "Lymphoma ": 6.231909913666382, "Mood swings ": 2.400183233757752, "Multiple organ dysfunction syndrome ": 2.8095887428918456, "Neoplasm malignant ": 2.3829166882263846, "Oedema peripheral ": 2.315672842128636, "Oesophageal varices haemorrhage ": 38.12947358924573, "Pancreatitis acute ": 2.857094945402418, "Photosensitivity reaction ": 2.332324622538988, "Portal vein thrombosis ": 15.421635932283817, "Product complaint ": 2.159330908377829, "Renal impairment ": 4.034343000103323, "Septic shock ": 3.187501681052547, "Spontaneous bacterial peritonitis ": 47.82313725936973, "Treatment failure ": 15.409961112093988, "Treatment noncompliance ": 3.1921722220004702, "Unevaluable event ": 2.45048167784442, "Upper gastrointestinal haemorrhage ": 2.09455964634024, "Viral load increased ": 23.913711484866848, "Virologic failure ": 24.4060372416836}
\ No newline at end of file
+{"Acute kidney injury": 2.587392476279438, "Angioedema": 3.835539714065976, "Atrial fibrillation": 3.154099036720609, "Blood glucose increased": 2.143764055540013, "Completed suicide": 19.66567288460777, "Diabetes mellitus": 7.759073765927343, "Diabetes mellitus inadequate control": 24.894974495762845, "Drug interaction": 3.1260122672941804, "Hyperkalaemia": 6.013446941180351, "Hypoglycaemia": 13.789757839468932, "Infusion site extravasation": 175.88972800076286, "Lactic acidosis": 21.52830886033204, "Loss of consciousness": 2.3881972117019874, "Pemphigoid": 36.49822139696445, "Product monitoring error": 290.8439585151044, "Toxicity to various agents": 5.338830471858231, "Tremor": 2.0420126053534013, "Wrong patient received product": 94.19399297381086}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1005.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1005.json
index 57ef2b66fcc..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1005.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1005.json
@@ -1 +1 @@
-{"Pancreatitis acute ": 73.61796610087383}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1006.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1006.json
index 23c0dbb3bc6..d3238296739 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1006.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1006.json
@@ -1 +1 @@
-{"Abnormal menstrual clots ": 3.0774631601850557, "Adenovirus test ": 21.554777269242955, "Administration site erythema ": 2.0970263571297507, "Administration site lymphadenopathy ": 6.494326833387717, "Administration site movement impairment ": 3.3978104585021973, "Administration site pruritus ": 2.031268287377796, "Administration site rash ": 2.7611885244173955, "Administration site warmth ": 3.717820463072367, "Adnexa uteri pain ": 2.3914589139178872, "Alanine aminotransferase normal ": 35.163367348266625, "Allergy to vaccine ": 2.107029929152417, "Angiogram ": 2.000706393077717, "Angiogram pulmonary abnormal ": 30.57591402254277, "Anion gap ": 4.402474394814995, "Anticoagulant therapy ": 4.841745469737655, "Application site movement impairment ": 2.416036232546306, "Application site reaction ": 2.279170478242345, "Application site swelling ": 3.037670080509844, "Arthralgia ": 2.440285985882721, "Aspartate aminotransferase normal ": 28.635263974628977, "Axillary mass ": 3.713326017239901, "Axillary pain ": 4.556141088834684, "Bacille Calmette-Guerin scar reactivation ": 7.613017381293346, "Basophil percentage decreased ": 4.153048058998574, "Bell's palsy ": 2.73625648598697, "Blood alkaline phosphatase normal ": 39.35756489622921, "Blood bilirubin normal ": 52.301057913101545, "Blood calcium normal ": 19.006821888465364, "Blood chloride normal ": 36.95909529489059, "Blood creatinine normal ": 35.01662930204063, "Blood culture ": 11.423906227210628, "Blood culture negative ": 2.650084345537598, "Blood glucose normal ": 8.519953765621457, "Blood lactic acid ": 3.5993153147261423, "Blood potassium normal ": 46.0654465647587, "Blood sodium normal ": 37.80485096167001, "Blood test ": 13.544281500525624, "Blood test normal ": 27.38759860677889, "Blood urea normal ": 35.15792648551141, "Body temperature increased ": 2.7868887318038764, "Breakthrough COVID-19 ": 13.972936893647397, "Breast engorgement ": 2.0249198067576746, "COVID-19 immunisation ": 16.547311100504448, "COVID-19 pneumonia ": 2.2642297340864506, "Carbon dioxide normal ": 24.373665170271423, "Cardiac discomfort ": 3.5631494543020046, "Cardiac monitoring ": 3.4914295347383075, "Cardiac stress test ": 6.002965258409991, "Chest X-ray ": 20.15192392980808, "Chest X-ray normal ": 46.30816705880069, "Chills ": 3.94496462774514, "Computerised tomogram ": 24.183180943652648, "Computerised tomogram abdomen abnormal ": 8.962391645816457, "Computerised tomogram head ": 5.451270457966126, "Computerised tomogram head abnormal ": 8.634602311091168, "Computerised tomogram head normal ": 28.57885678946372, "Computerised tomogram normal ": 7.83115241830028, "Computerised tomogram thorax ": 6.532777321720162, "Computerised tomogram thorax abnormal ": 6.123801611806822, "Computerised tomogram thorax normal ": 28.635263974628977, "Delirium febrile ": 2.714958654070412, "Dermal filler reaction ": 8.075601187856439, "Diaphragmalgia ": 2.045932338497128, "Differential white blood cell count ": 28.283889350267376, "Dysmenorrhoea ": 2.465760366867761, "Ear inflammation ": 2.511613102518337, "Echocardiogram ": 18.47764831145529, "Echocardiogram abnormal ": 2.512676466444255, "Echocardiogram normal ": 22.650086034836544, "Ejection fraction normal ": 33.36303800782902, "Electrocardiogram ": 14.818124630254111, "Electrocardiogram normal ": 17.320045858299704, "Electroencephalogram ": 3.5556317021451456, "Erythema migrans ": 2.006440008413042, "Exercise tolerance decreased ": 2.072699732365172, "Exposure to SARS-CoV-2 ": 4.5752358474877886, "Extensive swelling of vaccinated limb ": 11.76699274190488, "Eye infarction ": 2.621690883762172, "Facial discomfort ": 2.0402698263044114, "Fatigue ": 2.715820605658442, "Feeling hot ": 3.1717920327818945, "Fibrin D dimer ": 12.58163461267607, "Full blood count ": 12.740736311781546, "Full blood count normal ": 9.196383097252456, "Glomerular filtration rate normal ": 16.29216072354908, "Growing pains ": 3.138813132716742, "Haematocrit normal ": 20.527430928801905, "Haemoglobin normal ": 17.038389992662317, "Headache ": 2.5881114100736435, "Heart rate ": 2.476791207621503, "Heavy menstrual bleeding ": 2.476769605779709, "Hypomenorrhoea ": 2.151072070477509, "Immediate post-injection reaction ": 10.158963537880574, "Immunisation reaction ": 4.877326270163718, "Immunoglobulin therapy ": 4.260687219835851, "Impaired work ability ": 2.01232923308311, "Influenza ": 3.345594059956712, "Influenza A virus test negative ": 28.879922193631675, "Influenza B virus test ": 27.96292819423499, "Influenza like illness ": 2.058936877873601, "Influenza virus test negative ": 10.471255506495, "Injected limb mobility decreased ": 4.654410079293224, "Injection site discomfort ": 3.050744018309254, "Injection site erythema ": 8.616017183577258, "Injection site haematoma ": 4.845505468415294, "Injection site hypersensitivity ": 2.7052043189146726, "Injection site hypoaesthesia ": 2.269605912220934, "Injection site induration ": 8.571263013660637, "Injection site inflammation ": 10.07762846519463, "Injection site joint movement impairment ": 2.9882110432863307, "Injection site lymphadenopathy ": 3.386726191867222, "Injection site macule ": 2.2311628493172946, "Injection site movement impairment ": 4.564479292133886, "Injection site muscle weakness ": 2.8505726202188577, "Injection site oedema ": 2.069742848874513, "Injection site pain ": 5.90173206900908, "Injection site paraesthesia ": 2.5540565169392084, "Injection site pruritus ": 9.135957619599882, "Injection site rash ": 2.983290176891367, "Injection site reaction ": 4.064794001536034, "Injection site swelling ": 9.323067276692438, "Injection site warmth ": 11.3519024947709, "Inner ear inflammation ": 2.313142173174804, "Intensive care ": 3.4645391636429013, "Interchange of vaccine products ": 2.5343236687583945, "Intermenstrual bleeding ": 2.435020914600985, "Itching scar ": 2.00187227119521, "Laboratory test ": 34.9703162556709, "Laboratory test normal ": 12.24010533147733, "Limb discomfort ": 4.774105907953095, "Local reaction ": 3.344580535381688, "Lymph node pain ": 3.15479936222887, "Lymphadenopathy ": 3.74661948790408, "Magnetic resonance imaging ": 16.14723547511517, "Magnetic resonance imaging head ": 3.9302928745301777, "Magnetic resonance imaging head normal ": 15.60778192516601, "Magnetic resonance imaging heart ": 6.649218182807665, "Magnetic resonance imaging normal ": 11.364666689149423, "Malaise ": 3.146917849081165, "Maternal exposure during breast feeding ": 2.548655073136345, "Mechanical urticaria ": 9.034999274725912, "Menometrorrhagia ": 2.391940829647871, "Menstrual cycle management ": 2.4609535884259084, "Menstrual discomfort ": 2.68963012723821, "Menstrual disorder ": 2.794989298768743, "Menstruation delayed ": 2.151318453640999, "Menstruation irregular ": 2.682871572706525, "Metabolic function test ": 38.15829329414724, "Metabolic function test normal ": 11.364666689149423, "Multisystem inflammatory syndrome ": 2.158726640069617, "Multisystem inflammatory syndrome in adults ": 2.571117724806057, "Muscle swelling ": 2.872749278880861, "Myalgia ": 3.479196381544742, "Myelin oligodendrocyte glycoprotein antibody-associated disease ": 2.5794529249278506, "Myocarditis ": 3.287676577148453, "Myopericarditis ": 4.962108452054618, "Nasal herpes ": 2.502915692613385, "Neuralgic amyotrophy ": 2.995391023354006, "New daily persistent headache ": 3.4537518657525337, "Oligomenorrhoea ": 2.5452551465113684, "Ovulation pain ": 2.47919315784784, "Pain in extremity ": 2.219818141371047, "Painful respiration ": 2.29159335936884, "Platelet count normal ": 13.620252842493365, "Polymenorrhoea ": 2.8110501066686715, "Positive airway pressure therapy ": 4.225397257192262, "Post vaccination syndrome ": 2.5608776459681635, "Post-acute COVID-19 syndrome ": 2.245101233871936, "Postmenopausal haemorrhage ": 2.570973484005285, "Premenstrual pain ": 2.583839208313918, "Premenstrual syndrome ": 2.114200739273832, "Presyncope ": 2.5206626242489656, "Procalcitonin ": 19.325597411746887, "Pulmonary pain ": 2.231196819630564, "Puncture site erythema ": 2.9954461370993446, "Puncture site oedema ": 2.2103855848006937, "Puncture site pain ": 2.131367919443887, "Puncture site pruritus ": 2.712860085117506, "Puncture site reaction ": 4.278361561000895, "Puncture site swelling ": 2.334604192650971, "Pyrexia ": 2.677475144843428, "Respiratory syncytial virus test negative ": 7.866421370963003, "Rest regimen ": 3.204546507841324, "SARS-CoV-2 antibody test negative ": 2.1231405514654367, "SARS-CoV-2 test ": 2.6901574532595385, "SARS-CoV-2 test positive ": 2.915732353420042, "Scan with contrast abnormal ": 13.10763368182544, "Shoulder injury related to vaccine administration ": 2.004488703120628, "Sick leave ": 3.492837131445471, "Skin warm ": 2.1447636384831417, "Specialist consultation ": 2.011614554980645, "Tenderness ": 2.4151363067476264, "Thrombectomy ": 2.1051000148635497, "Thyroiditis subacute ": 2.0226912975854536, "Tinnitus ": 2.052292351488166, "Trichodynia ": 2.712860085117506, "Troponin ": 9.75811868638285, "Troponin I ": 5.679679993878258, "Troponin normal ": 40.46109610907418, "Ultrasound Doppler ": 9.24490278161382, "Ultrasound Doppler abnormal ": 5.154628377720705, "Ultrasound scan ": 18.04575208717693, "Urine analysis ": 21.33904342330189, "Urine analysis normal ": 9.96885882609656, "Urticaria chronic ": 6.508354758827746, "Urticaria physical ": 3.776076810247838, "Uterine pain ": 2.156346582957462, "Vaccination complication ": 2.737371319048978, "Vaccination site anaesthesia ": 3.402988927522148, "Vaccination site bruising ": 2.9132756661457933, "Vaccination site dermatitis ": 2.478082636637355, "Vaccination site discharge ": 2.847796623496854, "Vaccination site discolouration ": 3.847075015678275, "Vaccination site discomfort ": 3.5853665329324613, "Vaccination site dysaesthesia ": 3.110252584768116, "Vaccination site eczema ": 2.163961480796769, "Vaccination site erythema ": 9.50183620078729, "Vaccination site exfoliation ": 3.776076810247838, "Vaccination site haematoma ": 2.303944388374126, "Vaccination site haemorrhage ": 2.489998353472764, "Vaccination site hyperaesthesia ": 5.359740093047969, "Vaccination site hypersensitivity ": 3.1837434837406797, "Vaccination site induration ": 4.373666528166975, "Vaccination site infection ": 5.815067105576863, "Vaccination site inflammation ": 4.0641514444245015, "Vaccination site irritation ": 4.449396973750255, "Vaccination site joint erythema ": 5.072045065794659, "Vaccination site joint movement impairment ": 2.9523222063154257, "Vaccination site joint pain ": 2.899476044892268, "Vaccination site joint swelling ": 5.149752862700527, "Vaccination site joint warmth ": 4.295542955474835, "Vaccination site lymphadenopathy ": 4.465612296887367, "Vaccination site macule ": 14.535878247339587, "Vaccination site mass ": 2.2159526604587776, "Vaccination site movement impairment ": 5.594706912012897, "Vaccination site oedema ": 4.7061445608945, "Vaccination site pain ": 3.6096616179270713, "Vaccination site papule ": 2.3307675183328644, "Vaccination site paraesthesia ": 2.19987097405362, "Vaccination site plaque ": 16.638904428226112, "Vaccination site pruritus ": 9.211307139784228, "Vaccination site pustule ": 3.384164207232451, "Vaccination site rash ": 12.846320600044182, "Vaccination site reaction ": 8.15299973998501, "Vaccination site swelling ": 7.094089261821529, "Vaccination site urticaria ": 9.8804098336149, "Vaccination site vesicles ": 2.284806062540618, "Vaccination site warmth ": 8.898443574370981, "Vaccine breakthrough infection ": 14.240635620540903, "Vaccine positive rechallenge ": 4.045565735356236, "Weight bearing difficulty ": 3.024007100320395, "White blood cell count normal ": 30.033412621196096, "X-ray ": 21.33904342330189}
\ No newline at end of file
+{"Completed suicide": 102.5292937671624, "Intentional product misuse": 101.95006512172726, "Toxicity to various agents": 89.14388211807089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1007.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1007.json
index 5f331a494a0..34e2cc7d755 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1007.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1007.json
@@ -1 +1 @@
-{"Activated partial thromboplastin time prolonged ": 5.483916253970602, "Acute respiratory failure ": 16.77516946998773, "Adenovirus infection ": 11.536564054113493, "Ankle fracture ": 2.7369788983894483, "Apnoea ": 8.790394260314505, "Appendicitis ": 2.5298747996263806, "Arachnoiditis ": 96.45144110812238, "Aspiration ": 33.10227313430038, "Atelectasis ": 33.12181758665838, "Autism spectrum disorder ": 5.350631067002635, "Back pain ": 3.958708126764131, "Bacteraemia ": 3.8972613411075407, "Brain death ": 11.070390026079266, "Brain injury ": 8.162099182819983, "Bronchial secretion retention ": 60.50588926688396, "Bronchiolitis ": 21.283858879245017, "Bronchitis ": 3.549074768555447, "COVID-19 pneumonia ": 3.458310336004075, "CSF pressure increased ": 767.8668887336981, "CSF protein increased ": 130.96199138448975, "CSF test abnormal ": 61.07861641853554, "Cardiac arrest ": 4.748934470221276, "Cardio-respiratory arrest ": 7.501035723460521, "Cerebrospinal fluid leakage ": 177.95860879228582, "Choking ": 6.074218162951523, "Chronic respiratory failure ": 83.49504945234207, "Clostridium difficile infection ": 2.439469699591208, "Death ": 2.7638602143759345, "Dehydration ": 2.5487356148541225, "Device dislocation ": 22.001517168446597, "Device related infection ": 4.573279179665016, "Dysphagia ": 3.8667067467362215, "Enterovirus infection ": 171.5457392307427, "Faecaloma ": 6.859016139206288, "Femur fracture ": 16.382098824429015, "Foot fracture ": 2.061476419417024, "Gait inability ": 6.485456111872511, "Gastroenteritis ": 3.977676834297863, "Gastroenteritis viral ": 8.37322402749472, "Gastrointestinal infection ": 18.743216724599115, "Hip fracture ": 4.253945306229179, "Hydrocephalus ": 37.80372092143507, "Hyperthermia ": 2.1185299658147625, "Hypotonia ": 2.3214445971719915, "Hypoxia ": 2.6077343636746, "Increased appetite ": 2.183575142400596, "Increased bronchial secretion ": 32.878367472672025, "Infection ": 3.2193352830439386, "Intracranial pressure increased ": 24.771798699238182, "Joint dislocation ": 19.576110150056387, "Kyphosis ": 19.4294991677899, "Lower limb fracture ": 6.242113081147199, "Malnutrition ": 15.777376221445708, "Mechanical ventilation complication ": 111.4787948553636, "Meningitis ": 10.622511670869004, "Meningitis aseptic ": 15.887930131253365, "Meningitis bacterial ": 40.26448965100187, "Meningitis chemical ": 162.41417442634565, "Metapneumovirus infection ": 58.59525912964613, "Mobility decreased ": 2.969403561972793, "Motor dysfunction ": 19.01756437435784, "Muscle contracture ": 22.321433396426976, "Muscle tightness ": 3.501321337847505, "Muscular weakness ": 2.584331345227675, "Nasopharyngitis ": 2.170590741597012, "Nephrolithiasis ": 5.845623521259975, "Neurological examination abnormal ": 194.5464689476435, "Neurological procedural complication ": 1658.1405853221372, "Oxygen saturation decreased ": 5.296742676414011, "Parainfluenzae virus infection ": 51.23897082039803, "Physical examination abnormal ": 263.044119806319, "Pleocytosis ": 61.1953986922888, "Pneumonia ": 7.763580444698442, "Pneumonia aspiration ": 7.300812164484346, "Pneumonia bacterial ": 5.863496938056331, "Pneumonia respiratory syncytial viral ": 60.99532952499428, "Pneumonia viral ": 25.57541487592364, "Pneumothorax ": 11.107134247403348, "Polyuria ": 2.795973211520785, "Post lumbar puncture syndrome ": 6081.1811400013785, "Post procedural complication ": 57.565698813811885, "Post procedural fever ": 204.8236967187005, "Post procedural haematoma ": 19.88214714778649, "Post procedural haemorrhage ": 7.181089276620807, "Post procedural infection ": 23.51661666310653, "Post procedural swelling ": 107.72222377474203, "Prescribed underdose ": 7.158483424727773, "Procedural anxiety ": 278.9977731143591, "Procedural complication ": 72.53106069592043, "Procedural headache ": 469.6356570752501, "Procedural nausea ": 191.43637376659936, "Procedural pain ": 120.87952076780572, "Procedural vomiting ": 231.11594451421843, "Protein total increased ": 13.204125319543, "Protein urine present ": 10.162907183565522, "Proteinuria ": 7.17713036823594, "Pseudomonas infection ": 8.923477398241392, "Radicular pain ": 83.89137901624666, "Renal tubular acidosis ": 16.411660718642572, "Respiratory arrest ": 8.090625846430132, "Respiratory disorder ": 19.68683494139902, "Respiratory distress ": 7.306733321550579, "Respiratory failure ": 9.519971672657489, "Respiratory syncytial virus infection ": 45.103951379338014, "Respiratory tract infection ": 31.54222771694424, "Respiratory tract infection viral ": 47.9386322924686, "Respiratory tract procedural complication ": 1034.927608000197, "Rhinovirus infection ": 215.56437940435765, "Road traffic accident ": 2.320446465359991, "SARS-CoV-2 test positive ": 4.789618612811015, "Salivary hypersecretion ": 5.2650368230409965, "Sciatica ": 2.935158369290608, "Scoliosis ": 396.9027946407125, "Secretion discharge ": 6.885173133584046, "Sepsis ": 3.006695459368724, "Sinus tachycardia ": 2.5668289144229326, "Spinal deformity ": 69.51131926309743, "Spinal disorder ": 9.500529832406912, "Spinal fusion surgery ": 18.415399745440105, "Spinal implantation ": 859.3049643898396, "Spinal muscular atrophy ": 3483.2606846503195, "Spinal pain ": 3.7459468304097903, "Sudden death ": 4.056151798283298, "Therapeutic product effect decreased ": 2.681196153624524, "Therapeutic response shortened ": 12.41470003414732, "Tibia fracture ": 13.395104867026284, "Tracheostomy ": 23.75630104692188, "Tracheostomy malfunction ": 263.044119806319, "Traumatic lumbar puncture ": 2547.739059467472, "Upper respiratory tract infection ": 5.099917008781794, "Viral infection ": 13.003892029886169, "Viral upper respiratory tract infection ": 18.891870948840715, "Vital capacity decreased ": 66.0556316173409, "Weight gain poor ": 31.273888111899563}
\ No newline at end of file
+{"Abortion spontaneous": 2.653979182249274, "Acne": 2.971094238981685, "Arthritis": 2.6536412187940126, "Breast cancer": 2.2343051311679014, "Breast cancer female": 20.27669792555257, "C-reactive protein increased": 2.1787978560301577, "Crohn's disease": 4.497658652437914, "Dermatitis exfoliative generalised": 7.177791313020195, "Device issue": 13.528436062341603, "Eczema": 4.999146028610052, "Fungal infection": 4.237620919927919, "Hepatic cirrhosis": 5.020717179041319, "Infection": 2.071359809157869, "Injection site haemorrhage": 7.483320503453508, "Intestinal obstruction": 4.3474030201401, "Lung neoplasm malignant": 3.078402096828841, "Lymphoma": 9.180553763851163, "Maternal exposure during pregnancy": 2.2818829700024037, "Prostate cancer": 4.400558744395312, "Psoriasis": 52.66322628834445, "Psoriatic arthropathy": 11.409406826006387, "Skin disorder": 2.8866871735501904, "Skin exfoliation": 4.713151523368958, "Skin lesion": 3.21380542299721, "Skin plaque": 19.343395065319918, "Stress": 2.83542321950803, "Surgery": 3.848365977664933, "Therapeutic product effect decreased": 3.2939890061616617, "Therapeutic product effect incomplete": 2.7337508623495435, "Therapeutic response shortened": 64.98127031151897, "Tuberculosis": 6.911136707464373, "Unevaluable event": 14.622455339714728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1008.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1008.json
index e975b75de48..2ddcdf7ebe9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1008.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1008.json
@@ -1 +1 @@
-{"Acute generalised exanthematous pustulosis ": 11.07671652950718, "Acute kidney injury ": 8.422207320297622, "Aortic valve incompetence ": 11.268573145889905, "Ascites ": 2.1136240177036707, "Asthenia ": 3.9685167624373614, "Atrial fibrillation ": 2.971471402157264, "Atrioventricular block first degree ": 35.292927625036306, "Blood bicarbonate decreased ": 18.995486497641668, "Blood creatinine increased ": 4.861131845862096, "Blood potassium decreased ": 6.039902749214058, "Blood potassium increased ": 16.094187136185464, "Blood urea increased ": 7.348090767427529, "Bradycardia ": 4.588331015162281, "Bradykinesia ": 10.966886660036874, "Bundle branch block left ": 23.01533555110131, "Cardiac amyloidosis ": 112.6449002631122, "Cardiac failure ": 3.636681709964913, "Cardiac failure acute ": 7.21211825262986, "Cardiac failure chronic ": 15.220407114938345, "Cardioactive drug level increased ": 11.764740399343404, "Cardiomegaly ": 4.053404230326045, "Coagulopathy ": 4.447403936477113, "Cognitive disorder ": 3.055447068404584, "Coronary artery disease ": 2.121879978125937, "Dehydration ": 4.63280570699531, "Dementia ": 5.34560661643054, "Drug interaction ": 3.2508871332603007, "Drug reaction with eosinophilia and systemic symptoms ": 6.40340977636457, "Dyspnoea at rest ": 14.069321519260678, "Dysuria ": 3.1585164248025936, "Electrocardiogram QRS complex prolonged ": 22.613720660769097, "Electrocardiogram QT prolonged ": 2.033134358926629, "Electrocardiogram T wave peaked ": 125.96764329885842, "Electrocardiogram abnormal ": 6.0407738948376, "Electrolyte imbalance ": 4.82379326386435, "Exercise tolerance decreased ": 3.2848676507240726, "Fall ": 2.822373179836537, "Fluid retention ": 2.71226278834474, "Gastric polyps ": 23.037116044823573, "Glomerular filtration rate decreased ": 3.442983425662264, "Gynaecomastia ": 15.522617916415909, "Haematuria ": 2.502485500229438, "Heart failure with reduced ejection fraction ": 91.6620794935685, "Hiatus hernia ": 9.265685885806302, "Hyperkalaemia ": 53.296380247026285, "Hypokalaemia ": 4.438349673040297, "Hyponatraemia ": 10.753680909294111, "Hypophagia ": 4.001368138956946, "Hypotension ": 5.585144448530038, "Hypovolaemia ": 15.800302349654713, "Left ventricular dysfunction ": 7.442164055802391, "Medication error ": 3.736153846002881, "Metabolic acidosis ": 8.104403705802996, "Mitral valve incompetence ": 6.882078331051297, "Mobility decreased ": 2.240356063463286, "Motor dysfunction ": 9.763492882981032, "Multiple organ dysfunction syndrome ": 2.989912938021328, "Muscular weakness ": 2.534329561959896, "Neuroglycopenia ": 249.3962780602105, "Obstructive pancreatitis ": 53.42267375952956, "Oedema peripheral ": 3.818025650372767, "Oliguria ": 5.320506039465583, "Orthostatic hypotension ": 11.7506807097621, "Parkinsonism ": 9.596792245219186, "Premature delivery ": 3.490646309951432, "Product prescribing error ": 2.582734282324931, "Pulmonary congestion ": 5.505601221742188, "Pulmonary oedema ": 2.293647973691361, "Rales ": 6.71961083711728, "Renal impairment ": 2.7059326491478504, "Sedation ": 2.2512968587409645, "Sinus bradycardia ": 9.203078730037015, "Stevens-Johnson syndrome ": 12.230220316617617, "Tachypnoea ": 2.356091645541289, "Toxic epidermal necrolysis ": 2.25807257142071, "Transplant dysfunction ": 57.08350101015496, "Type 2 diabetes mellitus ": 2.373816391411525, "Urine output decreased ": 5.19943416198889, "Ventricular extrasystoles ": 3.746539828197271, "Ventricular tachycardia ": 5.605748626842942}
\ No newline at end of file
+{"Aggression": 75.87874501894635, "Agitation": 33.4324342605909, "Irritability": 30.746272970693337, "Middle insomnia": 108.16237748116951, "Product administered to patient of inappropriate age": 129.40971429495238, "Somnolence": 3.3420154094123924}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1009.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1009.json
index 3f56083d058..845cb003906 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1009.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1009.json
@@ -1 +1 @@
-{"Acne ": 2.8943809398626428, "Acute febrile neutrophilic dermatosis ": 6.634634804836901, "Acute lymphocytic leukaemia recurrent ": 16.003557433818624, "Acute pulmonary oedema ": 4.703200832599902, "Adverse event ": 11.495086735934722, "Anaemia ": 2.384579389336615, "Ascites ": 2.692870506318313, "Aspiration pleural cavity ": 197.14187567627616, "Atrial fibrillation ": 2.229927328934941, "Back disorder ": 2.2719091286628488, "Blast cell crisis ": 109.22375482219668, "Blast cell proliferation ": 220.94495881242807, "Blast crisis in myelogenous leukaemia ": 48.87093153735267, "Blood disorder ": 5.0115704348312615, "Bone marrow disorder ": 24.01807590942227, "Bone marrow failure ": 4.066230714832817, "Bone marrow transplant ": 57.5797450471399, "Bone pain ": 2.4044314156253144, "Cardiac disorder ": 2.8237789212132216, "Cardiac failure ": 4.0948822638290805, "Cardiac failure congestive ": 4.369320382554774, "Cardiomegaly ": 2.342140589692949, "Cellulitis ": 2.11163914374498, "Chronic myeloid leukaemia ": 31.67543986635461, "Chronic myeloid leukaemia recurrent ": 67.695276543408, "Chronic myeloid leukaemia transformation ": 63.33824132155883, "Chylothorax ": 246.4346928007508, "Clostridium difficile infection ": 2.302652651206349, "Colitis ": 5.147579309064161, "Cytomegalovirus colitis ": 7.747378279755652, "Cytomegalovirus enterocolitis ": 20.096597514153, "Cytopenia ": 14.195674988659032, "Death ": 3.0955379074819898, "Dialysis ": 2.0407428764158344, "Drug resistance ": 2.3768187423880542, "Dyspnoea exertional ": 2.163196769848902, "Electrocardiogram QT prolonged ": 3.005192238850612, "Enterocolitis ": 4.007591691421756, "Enterocolitis haemorrhagic ": 17.94287258450815, "Eye haemorrhage ": 2.001490514118895, "Fluid retention ": 13.009506275855774, "Full blood count decreased ": 12.560052394155456, "Gallbladder disorder ": 2.766935122549561, "Gastrointestinal haemorrhage ": 3.3973685983653867, "Gastrointestinal infection ": 3.700380359652028, "Gene mutation ": 30.13713785139111, "Generalised oedema ": 3.022556364643147, "Graft versus host disease ": 4.342558962680672, "Haematochezia ": 2.25613447702314, "Haematotoxicity ": 4.18291779009479, "Haemorrhage ": 2.173939979543705, "Haemothorax ": 9.280297829664793, "Hospitalisation ": 12.146825424779822, "Intentional product use issue ": 4.0174721438645, "Internal haemorrhage ": 4.193435703955299, "Intestinal haemorrhage ": 2.6777595367461493, "Iron deficiency anaemia ": 2.633098621141812, "Leukaemia ": 9.611546395556612, "Leukaemia recurrent ": 11.621405669090858, "Lower gastrointestinal haemorrhage ": 3.111106895934293, "Lung disorder ": 2.0766461174880537, "Lung infiltration ": 4.648382745863988, "Lymphocytosis ": 10.32387784063538, "Malignant neoplasm progression ": 11.37571149675828, "Nephrotic syndrome ": 4.129193005343136, "Neuropathy peripheral ": 2.753664306520925, "Oedema ": 2.8288642460091658, "Pancytopenia ": 5.441121560058406, "Pericardial effusion ": 37.59568427821048, "Peripheral arterial occlusive disease ": 5.747034098392515, "Philadelphia chromosome positive ": 192.5274851188784, "Platelet count decreased ": 2.82738743825597, "Platelet count increased ": 3.0776449567349133, "Platelet transfusion ": 16.00890211337492, "Pleural effusion ": 109.2133794519122, "Pleurisy ": 14.555241378223528, "Pneumonia ": 3.621915036173572, "Pneumonia fungal ": 4.469600005136266, "Prescribed underdose ": 52.94852112096044, "Pulmonary alveolar haemorrhage ": 2.164208839156093, "Pulmonary arterial hypertension ": 29.84099635259896, "Pulmonary congestion ": 2.0745240644969254, "Pulmonary hypertension ": 36.73884058237484, "Pulmonary oedema ": 35.82384011054767, "Rectal cancer ": 5.159626074196619, "Red blood cell count decreased ": 3.0586655438707, "Respiratory tract congestion ": 3.683894496107481, "Retinal haemorrhage ": 2.576803306524529, "Right ventricular failure ": 3.663126823974151, "Splenomegaly ": 4.41534119793763, "Stem cell transplant ": 26.569155703680966, "Subdural haematoma ": 3.095648272598268, "Therapeutic response decreased ": 4.488711423594883, "Therapy non-responder ": 4.272067117253211, "Thrombocytopenia ": 3.4909548383879643, "Transfusion ": 8.59006720776718, "Transplant ": 8.928009173052821, "Tumour lysis syndrome ": 3.2651310485254226, "White blood cell count abnormal ": 3.2217981393792985, "White blood cell count increased ": 3.625381617941589}
\ No newline at end of file
+{"Ammonia increased": 85.14768935177429, "Cardiac arrest": 5.691845298571863, "Cerebrovascular insufficiency": 1687.92266617122, "Cluster headache": 93.0829645908044, "Coma": 7.077070081568211, "Confusional state": 4.934083684780522, "Drug abuse": 8.448666755634182, "Drug interaction": 14.412439204413706, "Drug level increased": 21.253946300848245, "Electroencephalogram abnormal": 87.68644476337025, "Eye movement disorder": 46.17764180242136, "Inhibitory drug interaction": 199.73286981245587, "Miosis": 51.29912456556964, "Multiple organ dysfunction syndrome": 10.636908014887943, "Myoclonus": 24.15322610955697, "Overdose": 17.66334240346588, "Somnolence": 3.1921201048783825, "Toxicity to various agents": 19.5116998130631}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/101.json
index 217aa395fb5..913067e5f3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/101.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 3.432034511827625, "Abdominal distension ": 3.0218247559599405, "Adjustment disorder with depressed mood ": 113.06969794229198, "Adverse drug reaction ": 21.84387452660102, "Adverse reaction ": 12.46491837827897, "Alanine aminotransferase increased ": 2.3560331402429986, "Alopecia ": 4.916715467900437, "Amnesia ": 11.50680238375522, "Anti-cyclic citrullinated peptide antibody positive ": 33.096166370714364, "Arthropathy ": 12.876044526087918, "Aspartate aminotransferase increased ": 2.6935852788759296, "Autoimmune disorder ": 17.645462022278814, "Back injury ": 18.11018938569901, "Basal cell carcinoma ": 21.484128842708625, "Blepharospasm ": 59.4378117934347, "Blood cholesterol increased ": 21.31229026981577, "Blood parathyroid hormone decreased ": 77.84293364138503, "Breast cancer stage III ": 18.235486175493147, "Bursitis ": 16.22235912199517, "C-reactive protein ": 58.05933439558506, "C-reactive protein abnormal ": 21.789986044552595, "C-reactive protein increased ": 13.370135687516507, "Coeliac disease ": 15.557613018461916, "Condition aggravated ": 2.8278864145491256, "Confusional state ": 2.6737909583585724, "Contraindicated product administered ": 15.695889562123552, "Cytokine storm ": 66.60349547674689, "Decreased appetite ": 2.591977508052677, "Deep vein thrombosis postoperative ": 8.384900697958118, "Delirium ": 15.28440478114908, "Disability ": 3.594502714886528, "Discomfort ": 9.890262784334508, "Dislocation of vertebra ": 221.507324583466, "Disseminated intravascular coagulation ": 3.682433240215802, "Drug eruption ": 5.853536931596886, "Drug hypersensitivity ": 11.75709119040272, "Drug intolerance ": 5.091118304412586, "Drug tolerance decreased ": 27.00138262471977, "Drug-induced liver injury ": 4.86332378173412, "Dry mouth ": 3.4830221569089703, "Duodenal ulcer perforation ": 23.935253822625956, "Dyspepsia ": 3.7391949386541614, "Enthesopathy ": 96.69622785994478, "Epilepsy ": 10.010226227238338, "Facet joint syndrome ": 44.73696129518514, "Fibromyalgia ": 12.549137230118596, "Finger deformity ": 24.512138915914203, "Folliculitis ": 13.266354768790489, "Gait disturbance ": 4.878979213777744, "Gait inability ": 7.760141213654442, "Gastrointestinal disorder ": 3.0133072435261083, "Gastrooesophageal reflux disease ": 6.037412219410965, "General physical health deterioration ": 5.652607483802892, "Glossodynia ": 5.044314927048245, "Granuloma skin ": 113.51445573635232, "Grip strength decreased ": 93.42765945488998, "Hand deformity ": 13.597033352859649, "Helicobacter infection ": 14.214965474978568, "Hepatic enzyme increased ": 6.670186334260973, "Hip arthroplasty ": 19.70174355969116, "Hypercalcaemia ": 16.766447692907377, "Hypercholesterolaemia ": 3.1427390531804567, "Hypersensitivity ": 3.161166247713074, "Hypoaesthesia ": 3.4200725946268364, "Incorrect route of product administration ": 4.563710557295238, "Inflammation ": 6.198283395343084, "Infusion related reaction ": 13.742923219633482, "Injury ": 10.427894900771989, "Iron deficiency ": 16.683504571789697, "Joint swelling ": 5.527664314302268, "Knee arthroplasty ": 18.174431140073462, "Lip dry ": 7.089402273940031, "Live birth ": 28.497321730821493, "Liver injury ": 5.634168981451155, "Loss of personal independence in daily activities ": 2.978394408819015, "Lower limb fracture ": 16.03664259157772, "Maternal exposure during pregnancy ": 2.6306432381254594, "Memory impairment ": 3.471302949247177, "Migraine ": 2.620634789629685, "Mobility decreased ": 12.221507413573692, "Muscle injury ": 21.68880441626898, "Muscular weakness ": 3.1031281553987, "Musculoskeletal pain ": 9.06383803522002, "Musculoskeletal stiffness ": 10.823090623686443, "Night sweats ": 2.2905177900150364, "Obesity ": 6.346264408954157, "Osteoarthritis ": 2.873053991334549, "Panniculitis ": 53.17751302090653, "Pemphigus ": 2.069948935221054, "Pericarditis ": 5.153502246351762, "Peripheral swelling ": 3.2941311668734694, "Peripheral venous disease ": 21.312116555646824, "Prescribed overdose ": 3.014320009463184, "Product quality issue ": 10.715493763558364, "Product use in unapproved indication ": 2.838507746192976, "Product use issue ": 2.3079170981950936, "Psoriatic arthropathy ": 25.479445587990757, "Rash pruritic ": 2.1632925714268985, "Red blood cell sedimentation rate ": 447.2689026325131, "Red blood cell sedimentation rate abnormal ": 5.828459560207387, "Red blood cell sedimentation rate increased ": 6.650550715651783, "Retroperitoneal haematoma ": 19.220423831318243, "Rheumatic fever ": 156.28610650017237, "Rheumatoid arthritis ": 7.7303399343699954, "Rheumatoid factor positive ": 69.50122848091762, "Sciatica ": 6.610966849558594, "Septic shock ": 2.0968844127904083, "Shock haemorrhagic ": 6.352401593648557, "Skin abrasion ": 4.924091944392407, "Sleep disorder ": 5.225999522163675, "Sleep disorder due to general medical condition, insomnia type ": 11.305619946130903, "Swelling ": 2.01257633174931, "Swollen joint count increased ": 130.637047524376, "Synovitis ": 4.9177431661289726, "Systemic lupus erythematosus ": 2.329742859258386, "Taste disorder ": 7.716361181389326, "Therapeutic product effect decreased ": 10.591935002520287, "Treatment failure ": 6.552691013964545, "Weight decreased ": 2.161337933005101, "Wound ": 2.428873212538081}
\ No newline at end of file
+{"Pyrexia": 2.4572270141847503}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1010.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1010.json
index 55d92ddd42e..9a769f7b745 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1010.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1010.json
@@ -1 +1 @@
-{"Completed suicide ": 53.30328829485575, "Drug interaction ": 16.656255131491992}
\ No newline at end of file
+{"Anaemia": 2.415525757893432, "Ascites": 5.870984986841708, "Bradycardia": 8.356390750732139, "Death": 2.2323323476761026, "Drug ineffective": 5.700401037500559, "Drug interaction": 4.796295965875079, "Genotype drug resistance test positive": 117.6370637123594, "Hepatitis C": 72.37544742557667, "Hepatocellular carcinoma": 23.772727215694548, "Intentional dose omission": 99.27973837023455, "Product dose omission issue": 6.241568586349409, "Treatment failure": 27.035609476735512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1011.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1011.json
index 6fce224f0ba..e44988b5e21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1011.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1011.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 3.405736030382148, "Abnormal dreams ": 2.702998184368318, "Aggression ": 4.866415552809968, "Agitation ": 3.947008318390966, "Akinesia ": 60.21426549310371, "Apathy ": 2.131198435493688, "Aspiration ": 4.96983879617291, "Behaviour disorder ": 3.3670274828395783, "Choking ": 5.741959648652567, "Chromaturia ": 20.417729351749163, "Colitis microscopic ": 29.750259077171357, "Confusional state ": 4.2149965511639325, "Coordination abnormal ": 2.886576406507133, "Dehydration ": 2.268197778291246, "Delirium ": 4.6624987622591725, "Delusion ": 7.979028547149376, "Dementia ": 6.316883951515079, "Disease progression ": 3.296813932488486, "Disorientation ": 3.98730445254888, "Dopamine dysregulation syndrome ": 223.59585536084668, "Dyskinesia ": 30.289171692590585, "Dysphagia ": 20.125659654680128, "Dysstasia ": 5.676051046422579, "Dystonia ": 10.376329680771184, "Eating disorder ": 3.147996652888444, "Fall ": 4.120459383900854, "Feeding disorder ": 2.8815379729520307, "Femur fracture ": 3.138210888517888, "Fracture ": 5.769176202321302, "Freezing phenomenon ": 69.77136538612962, "Gait disturbance ": 3.877159360383796, "Gait inability ": 3.887561247038376, "Gambling disorder ": 38.28915995569985, "General physical health deterioration ": 3.102061139066422, "Hallucination ": 14.215252239620208, "Hallucination, auditory ": 3.80876539209585, "Hallucination, visual ": 20.04913758685486, "Hip fracture ": 3.4761500931010025, "Hyperkinesia ": 34.69701124488838, "Hypersexuality ": 88.54307920972444, "Hypokinesia ": 10.896466820444084, "Ileus ": 6.712852956988915, "Impulse-control disorder ": 33.91390444203331, "Incorrect dose administered ": 2.822161459869556, "Libido increased ": 20.785353313834342, "Motor dysfunction ": 5.006339917569944, "Movement disorder ": 5.751234979080472, "Muscle rigidity ": 16.086162379776695, "Musculoskeletal stiffness ": 3.3576030236252605, "Nervousness ": 3.309137962557001, "Neuroleptic malignant syndrome ": 3.49465684394376, "Nightmare ": 2.5097010206155463, "On and off phenomenon ": 227.7982496854132, "Oral mucosal discolouration ": 96.12341708593657, "Orthostatic hypotension ": 6.363507479889746, "Paralysis ": 4.33061368972657, "Paranoia ": 5.749322435225319, "Parkinson's disease ": 196.40166614224387, "Parkinsonian crisis ": 840.9120212576136, "Parkinsonism ": 7.755478468608146, "Pneumonia aspiration ": 8.312145081727648, "Product complaint ": 20.89472713737045, "Product prescribing error ": 4.978415313901908, "Product quality issue ": 2.3635455221260697, "Product residue present ": 10.629254931708047, "Product size issue ": 27.248367343819105, "Product supply issue ": 35.574906451178286, "Product use complaint ": 12.432151262976552, "Psychomotor hyperactivity ": 11.440689702563777, "Psychotic disorder ": 4.340717643291604, "Rhabdomyolysis ": 2.870390291627024, "Salivary hypersecretion ": 5.172281028187067, "Serotonin syndrome ": 2.6394945306584607, "Somnolence ": 2.161071015318711, "Speech disorder ": 4.318665600082211, "Stereotypy ": 36.10581657759274, "Sudden onset of sleep ": 37.57989661377093, "Therapeutic product effect decreased ": 2.360618906236981, "Therapeutic response shortened ": 38.01429181564257, "Therapy cessation ": 11.894260365424236, "Tremor ": 4.080310487581091, "Urinary tract infection ": 2.007486362317123, "Weight decreased ": 2.2238754835402563, "Wrong technique in product usage process ": 16.15472535526383}
\ No newline at end of file
+{"Acute graft versus host disease": 2.4761277403317647, "Acute leukaemia": 5.94417906878282, "Acute myeloid leukaemia": 2.274366398299472, "Acute pulmonary oedema": 2.364344183645966, "Adenovirus infection": 3.1526652185126327, "Anaemia": 2.562729945496668, "Antiphospholipid syndrome": 6.000474285740672, "Anuria": 5.161571915354844, "Aplastic anaemia": 25.878435733093163, "Ascites": 2.339815984259176, "Aspergillus infection": 3.880147154559228, "Atypical haemolytic uraemic syndrome": 216.2035817871704, "Azotaemia": 2.5298864992063663, "BK virus infection": 6.924371248208181, "Bacteraemia": 11.135772321064056, "Bacterial infection": 2.128518308891705, "Bacterial sepsis": 6.538036081634028, "Bilirubin conjugated increased": 3.0858455178312214, "Biopsy bone marrow": 46.72572520895088, "Blood albumin decreased": 3.501883505923867, "Blood alkaline phosphatase decreased": 14.828594614505556, "Blood bilirubin abnormal": 12.1997425493231, "Blood bilirubin increased": 3.414474464372369, "Blood calcium decreased": 3.178532224479821, "Blood creatinine abnormal": 15.787918175425444, "Blood creatinine decreased": 5.04732889681092, "Blood creatinine increased": 4.36955935726567, "Blood immunoglobulin G decreased": 10.976265228361523, "Blood iron increased": 10.418399079275746, "Blood lactate dehydrogenase abnormal": 101.25475683678924, "Blood lactate dehydrogenase decreased": 55.95308771719836, "Blood lactate dehydrogenase increased": 35.56879967520331, "Blood phosphorus increased": 3.859792334823805, "Blood product transfusion dependent": 118.65662604723413, "Blood urea abnormal": 11.147074865013968, "Blood urea increased": 3.46748611787698, "Blood urine present": 4.953933738107312, "Bone marrow disorder": 3.371383080703969, "Bone marrow failure": 7.493755737741591, "Bone marrow transplant": 23.43464587357212, "Brain death": 4.2979058698090045, "Brain herniation": 3.416566970038664, "Brain oedema": 2.6122143898852146, "Breakthrough haemolysis": 1445.457490807326, "Bronchopulmonary aspergillosis": 2.0063333890840225, "Budd-Chiari syndrome": 72.90268676269388, "C3 glomerulopathy": 223.61260198953107, "Catheter site infection": 9.406026243120222, "Catheter site pain": 5.933264638663731, "Cellulitis": 2.538291894183596, "Cerebral ischaemia": 2.447746903307313, "Cerebral thrombosis": 2.853484709085433, "Cholangitis": 2.144495550562955, "Cholecystitis": 4.313681649176924, "Cholecystitis acute": 2.094329216266205, "Cholelithiasis": 6.006089678134395, "Chromaturia": 13.039199139140528, "Clostridium difficile colitis": 2.1275989735741425, "Clostridium difficile infection": 3.511297795772576, "Complement factor C3 decreased": 116.1064159145342, "Complement factor C4 decreased": 40.65927226254822, "Complement factor abnormal": 398.8518921237636, "Complement factor decreased": 46.72572520895088, "Complement factor increased": 92.95526397805294, "Complications of transplanted kidney": 8.115480122109352, "Condition aggravated": 3.832067108249301, "Congenital aplasia": 3.273777648808284, "Coombs direct test positive": 13.324693482824175, "Coombs test positive": 36.2909655248785, "Critical illness": 24.626050630017804, "Cytomegalovirus infection": 2.9601174603673224, "Cytomegalovirus viraemia": 4.225045239394994, "Device related infection": 18.367194571694, "Device related sepsis": 10.21334632086281, "Dialysis": 9.081431989782336, "Disease complication": 6.432455918025368, "Disease recurrence": 4.047279806272615, "Drug level below therapeutic": 3.126765410390254, "End stage renal disease": 6.824515993377244, "Endocarditis": 5.166882071605969, "Enterococcal infection": 6.98605824612428, "Enterococcal sepsis": 20.68554313048513, "Epstein-Barr viraemia": 10.645571121736992, "Escherichia bacteraemia": 7.3440781025868835, "Escherichia infection": 3.5523368456675706, "Escherichia sepsis": 9.6912800331151, "Escherichia test positive": 19.18818422318626, "Escherichia urinary tract infection": 12.786681220250896, "Exposure during pregnancy": 4.946387181722742, "Exposure via breast milk": 2.735350139679372, "Extravascular haemolysis": 1918.0550230097808, "Eyelid ptosis": 2.856473011776091, "Foetal death": 2.007891850605745, "Foetal distress syndrome": 3.5170824529250417, "Foetal growth restriction": 2.2706051188267558, "Gallbladder disorder": 2.3024280036148377, "Gastroenteritis": 2.523809025454057, "Gastroenteritis viral": 4.56978182774044, "Gastrointestinal infection": 3.2075994660017324, "Gene mutation": 18.91004049148605, "Glomerular filtration rate decreased": 2.4095523909266183, "Glomerulonephritis": 4.512951320548305, "Glomerulonephritis membranoproliferative": 30.2219430048036, "Glomerulosclerosis": 14.064299512472532, "Graft loss": 50.34185270030078, "Graft versus host disease": 9.746955301883135, "Graft versus host disease in gastrointestinal tract": 3.329436792457472, "Haematocrit abnormal": 22.530966179682263, "Haematocrit decreased": 10.347416795639123, "Haematology test abnormal": 36.96601394173455, "Haematuria": 2.5780001041469798, "Haemodialysis": 5.911820949467304, "Haemoglobin abnormal": 23.822083738152024, "Haemoglobin decreased": 16.1909510063951, "Haemoglobinuria": 371.0713233141034, "Haemolysis": 192.63669030211705, "Haemolytic anaemia": 4.997996780678127, "Haemolytic uraemic syndrome": 58.00253211012946, "Haptoglobin abnormal": 420.2864946301463, "Haptoglobin decreased": 149.62864045334135, "Haptoglobin increased": 96.7641693229658, "Hepatic vein thrombosis": 30.212448172203665, "Hepatomegaly": 2.017432548750733, "Hospitalisation": 7.728899475393187, "Hypervolaemia": 7.352133293023371, "Immunosuppression": 6.51870339049537, "Inappropriate schedule of product administration": 6.137312415465194, "Incorrect dose administered": 8.971283679950222, "Infection": 4.413725064656599, "International normalised ratio decreased": 2.174529904158778, "Intestinal perforation": 3.804749126279064, "Intravascular haemolysis": 97.64772412391892, "Iron binding capacity total decreased": 64.20905133480194, "Iron overload": 32.5748009006544, "Jaundice": 2.716281644896358, "Kidney fibrosis": 11.360469572455772, "Kidney transplant rejection": 14.971613758345857, "Klebsiella infection": 7.061934218380748, "Laboratory test abnormal": 13.688188631590554, "Low birth weight baby": 2.093504109445224, "Malignant hypertension": 23.629400612034257, "Maternal exposure during breast feeding": 2.5023135859666623, "Mean cell volume increased": 11.097166853296049, "Meningitis": 6.48169470954232, "Meningitis meningococcal": 111.47147675039942, "Meningococcal bacteraemia": 207.6172862137629, "Meningococcal infection": 242.53582199273248, "Meningococcal sepsis": 335.03516497457986, "Microangiopathic haemolytic anaemia": 10.13724450905645, "Microangiopathy": 9.021246785125504, "Multimorbidity": 34.603260520172654, "Multiple organ dysfunction syndrome": 5.580668908764598, "Myasthenia gravis": 43.32096471376138, "Myasthenia gravis crisis": 156.909936016623, "Myelodysplastic syndrome": 9.820036981114429, "Necrotising fasciitis": 3.522004274252127, "Neurological decompensation": 6.681689329903158, "Neuromyelitis optica spectrum disorder": 43.26446860664242, "Neutrophil count increased": 2.2948521153665173, "Ocular icterus": 3.673485958480167, "Off label use": 3.975140808349325, "Oliguria": 2.399618766485799, "Pancytopenia": 2.0638205288533795, "Paroxysmal nocturnal haemoglobinuria": 340.7192574474543, "Pericardial effusion": 2.040191650791764, "Peritonitis": 3.4172283699725168, "Peritonitis bacterial": 7.496208646636274, "Plasmapheresis": 43.98045934079035, "Platelet count abnormal": 21.19407323280058, "Platelet count decreased": 6.190854079584632, "Platelet count increased": 3.2034060955091457, "Platelet transfusion": 10.44128039054577, "Pneumonia": 2.1410016555313267, "Pneumonia fungal": 2.915137879511847, "Pneumonia klebsiella": 8.782564074549969, "Poor venous access": 47.51892150649618, "Portal hypertension": 4.1963517272845, "Portal vein thrombosis": 5.933926847168577, "Post procedural haemorrhage": 4.402485750542063, "Posterior reversible encephalopathy syndrome": 2.649538772708413, "Postoperative wound infection": 2.700912882721453, "Pre-eclampsia": 7.786573897353309, "Pregnancy": 6.048436831128632, "Premature baby": 2.652551362143022, "Premature delivery": 2.4612756984391195, "Procalcitonin increased": 7.35630632121839, "Protein urine present": 2.1575844695219235, "Proteinuria": 6.013348570133013, "Pseudomonal sepsis": 12.82907096358088, "Pseudomonas infection": 6.819466328999691, "Pulmonary haemorrhage": 6.177247818407656, "Pulmonary oedema": 2.056905172934631, "Pyelonephritis": 2.1867712711530545, "Red blood cell count decreased": 3.362311482217105, "Red blood cell schistocytes present": 57.93569704911656, "Red blood cell transfusion": 24.23960366575733, "Red cell distribution width increased": 4.153040394037764, "Renal impairment": 4.038593604276172, "Renal transplant": 18.430307852359977, "Renal transplant failure": 46.27658008751978, "Renal tubular necrosis": 2.4203481696228786, "Respiratory failure": 2.466861979280231, "Respiratory tract infection": 4.524754743733026, "Respiratory tract infection viral": 6.818974218135487, "Reticulocyte count increased": 112.8348654957322, "Reticulocytosis": 45.09404940967795, "SARS-CoV-2 test positive": 4.834011252177906, "Scleroderma": 4.501496425232639, "Sepsis": 5.148848863189664, "Septic shock": 6.132060042057063, "Serum ferritin increased": 9.975134033475992, "Splenomegaly": 3.816596887148585, "Staphylococcal bacteraemia": 5.97143245501834, "Staphylococcal infection": 4.1486442267861685, "Staphylococcal sepsis": 10.167827608917351, "Suspected COVID-19": 8.458414630457044, "Symptom recurrence": 8.442018520477573, "Terminal state": 2.65513835926039, "Therapeutic response shortened": 4.097425052512239, "Thrombosis": 2.201730698082283, "Thrombotic microangiopathy": 55.74045386304496, "Thrombotic thrombocytopenic purpura": 3.3505197364234096, "Total complement activity decreased": 1001.1504906810244, "Total complement activity increased": 1157.985095658497, "Transfusion": 16.586307763841816, "Transfusion reaction": 20.783353595345805, "Transplant dysfunction": 9.881373936101664, "Transplant failure": 16.047203225828323, "Transplant rejection": 24.01069495121897, "Treatment noncompliance": 2.0414957837531635, "Unevaluable event": 3.080553072674873, "Upper respiratory tract infection": 4.288103232440969, "Urinary tract infection": 3.3317551982345126, "Urine output decreased": 2.3649344848141136, "Urosepsis": 2.5579307064636563, "Uterine leiomyoma": 2.7883942408498053, "Vascular device infection": 6.547592875523947, "Viral infection": 8.245395768988486, "Viral upper respiratory tract infection": 6.554397993441625, "White blood cell count abnormal": 2.6064630792949943}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1012.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1012.json
index c592709f144..f0f9ec207e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1012.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1012.json
@@ -1 +1 @@
-{"Abdominal pain ": 3.699398444925811, "Lactic acidosis ": 59.73239803503783, "Lipoatrophy ": 502.6771923047401, "Pancreatitis ": 11.936607486507832}
\ No newline at end of file
+{"Abscess limb": 27.31409671249371, "Acne": 3.2689167459726987, "Apnoea": 12.316305373243914, "Autoimmune thyroiditis": 14.285540665721554, "Blood alkaline phosphatase increased": 3.775187826782616, "Blood follicle stimulating hormone increased": 128.62945455890866, "Brain neoplasm": 32.95469153570535, "Cerebral infarction": 3.2111979663106425, "Condition aggravated": 2.159508749101408, "Contusion": 3.217902387412193, "Craniopharyngioma": 626.4802843396005, "Dehydration": 3.0904776507878875, "Diabetes mellitus": 5.843430255987122, "Disease recurrence": 10.460935280923849, "Drug abuse": 4.682739818575517, "Drug-induced liver injury": 10.747336530746834, "Eating disorder": 4.873289348430135, "Electrolyte imbalance": 9.670530122271732, "Enteritis": 18.699391002719537, "Epiphysiolysis": 722.4450930132522, "Fluid retention": 3.469666284043281, "Focal nodular hyperplasia": 148.3289695208738, "Focal segmental glomerulosclerosis": 77.75742512517103, "Gastrointestinal infection": 38.17183352978912, "Glucose tolerance impaired": 68.31341766630216, "Glycosylated haemoglobin increased": 3.522666981774041, "Head injury": 4.360510550601289, "Hepatic cirrhosis": 26.67277078647569, "Hepatic encephalopathy": 44.40357586596575, "Hepatic necrosis": 118.82859525466692, "Hepatomegaly": 11.912783809452428, "Hepatotoxicity": 13.493550296518764, "Hypoglycaemia": 2.576591646842401, "Hyponatraemic seizure": 386.1438015596223, "Hypophagia": 6.471100344467632, "Idiopathic intracranial hypertension": 241.6653602346964, "Increased appetite": 10.64671010133172, "Injection site atrophy": 88.83987535467666, "Injection site bruising": 10.547298936069764, "Injection site haemorrhage": 9.86754881187074, "Insulin resistance": 35.62490278094377, "Insulin-like growth factor increased": 278.57056558083264, "Intentional product misuse": 2.0170800566277776, "Intracranial pressure increased": 58.61924593764471, "Lower limb fracture": 9.307119250187409, "Meningioma": 56.60556288884906, "Myocardial fibrosis": 99.93713553370924, "Neoplasm recurrence": 93.530186464796, "Obstructive sleep apnoea syndrome": 93.44473712164935, "Oesophageal disorder": 49.96482074252936, "Off label use": 3.0642471280183825, "Pancreatitis acute": 6.354695258301056, "Panniculitis": 25.471415284247072, "Papilloedema": 23.66846701604428, "Pituitary tumour benign": 63.016160763225535, "Pleural adhesion": 349.2422085660759, "Product dose omission issue": 2.4982479017417747, "Product prescribing error": 10.437622371213305, "Protein-losing gastroenteropathy": 185.394968085309, "Scoliosis": 87.56623486100816, "Sleep apnoea syndrome": 37.13542725004547, "Snoring": 88.88864192627597, "Stress": 2.4625437485970263, "Sudden death": 18.379653723577015, "Sulphaemoglobinaemia": 1290.8221809123604, "Therapeutic response unexpected": 3.0383413805651585, "Tonsillar disorder": 271.355272624483, "Type 1 diabetes mellitus": 7.415810809777687, "Type 2 diabetes mellitus": 6.847951891042719, "Viral infection": 4.7167327495039295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1013.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1013.json
index 6f122d69b0e..151fa84343b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1013.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1013.json
@@ -1 +1 @@
-{"Abdominal abscess ": 6.960912366184648, "Abdominal operation ": 11.840779213632006, "Abortion infected ": 88.12870733460751, "Abortion spontaneous ": 4.548898709347866, "Abscess ": 5.931996595032327, "Abscess intestinal ": 11.700579230958237, "Abscess limb ": 2.3209900731435438, "Acarodermatitis ": 6.920993015896301, "Accident ": 2.0397386364029297, "Accident at work ": 5.090528858433591, "Accidental exposure to product ": 6.574266998270634, "Acne ": 2.3471767851152108, "Actinic keratosis ": 2.5809630700901924, "Adenocarcinoma ": 4.438624776624523, "Adenocarcinoma of colon ": 14.127170974809578, "Alopecia areata ": 4.546974606476146, "Anal abscess ": 17.37110528243891, "Anal cancer ": 12.855936280553156, "Anal fissure ": 2.3109883352988483, "Anal fistula ": 31.5891877218104, "Anastomotic stenosis ": 35.5262269502468, "Ankylosing spondylitis ": 3.1199058524417875, "Anogenital warts ": 7.007751084239879, "Anorectal disorder ": 3.557080651784194, "Antinuclear antibody positive ": 2.854883889814624, "Antiphospholipid antibodies positive ": 10.04441511834412, "Aortic dissection ": 3.325574829564992, "Appendicectomy ": 3.8059938970856826, "Arthritis ": 3.6405362883350216, "Arthropod bite ": 2.9130739977496747, "Atypical mycobacterial infection ": 3.319029795260676, "B-cell lymphoma ": 4.991420214786683, "Basal cell carcinoma ": 8.330572904961754, "Bladder neoplasm ": 5.8638801915177385, "Bladder transitional cell carcinoma ": 11.079576587519878, "Breast cancer ": 4.344058011181831, "Breast mass ": 2.617489181329035, "Breast neoplasm ": 8.776848910864139, "Bronchitis ": 2.15648258790678, "Caesarean section ": 2.4616034414355474, "Cardiac operation ": 2.628154024560199, "Cellulitis ": 4.3964861939240265, "Cervical dysplasia ": 7.805708883577505, "Cervical vertebral fracture ": 2.2355472941953085, "Cervix carcinoma ": 2.134880953971502, "Chemotherapy ": 3.697481047054121, "Chikungunya virus infection ": 49.95849854468705, "Cholangitis sclerosing ": 7.421446259978675, "Cholecystectomy ": 5.7961412092404005, "Cholelithiasis ": 2.045257067996521, "Chronic disease ": 26.21151830536997, "Chronic lymphocytic leukaemia ": 2.3991604494744405, "Chronic myeloid leukaemia ": 2.346138567019594, "Clear cell renal cell carcinoma ": 4.801484228443972, "Clostridial infection ": 5.705236537077241, "Clostridium difficile infection ": 6.18318996170692, "Coccidioidomycosis ": 9.334452148806136, "Coccydynia ": 6.045530878668987, "Colectomy ": 17.507295587014674, "Colitis ulcerative ": 19.80281446318024, "Colon cancer ": 5.552560327019312, "Colorectal adenoma ": 4.349670037640452, "Colostomy ": 5.436819374679723, "Contraindication to vaccination ": 23.572072984803462, "Coronary arterial stent insertion ": 2.0227760323496184, "Crohn's disease ": 131.31561946596375, "Cutaneous T-cell lymphoma ": 15.99533942264466, "Cutaneous lupus erythematosus ": 7.183607367704875, "Cutaneous vasculitis ": 4.006131818011896, "Cytomegalovirus colitis ": 2.9818221076560363, "Dactylitis ": 15.366639016387698, "Decreased immune responsiveness ": 3.09993640198383, "Defaecation urgency ": 6.1005318686765335, "Dengue fever ": 7.110031173772447, "Dermatitis atopic ": 2.10192665890181, "Dermatitis exfoliative ": 4.428765566129229, "Dermatitis exfoliative generalised ": 4.55929474361749, "Dermatitis psoriasiform ": 2.7093565402621667, "Device defective ": 5.540496540404582, "Device deployment issue ": 40.498033954947694, "Device issue ": 4.895360930119673, "Device leakage ": 3.751758283657114, "Diarrhoea haemorrhagic ": 2.803135681677146, "Dilated cardiomyopathy ": 4.698417020725785, "Disability ": 2.4069482860646376, "Diverticulitis ": 3.0252366985001715, "Drug delivery system malfunction ": 5.531785482182477, "Drug exposure before pregnancy ": 5.010723766828972, "Drug ineffective ": 3.206103955763131, "Drug level below therapeutic ": 20.096254800846705, "Drug level decreased ": 11.686140961089244, "Drug specific antibody ": 3.96007700881108, "Dysplasia ": 6.553030304113835, "Ear infection ": 2.352844292046478, "Eczema ": 2.0403560357318518, "Endometrial cancer ": 5.815611036089845, "Endometriosis ": 2.597790926746449, "Endometritis ": 9.334452148806136, "Enterocutaneous fistula ": 16.335500742435432, "Enterostomy ": 31.851220588339142, "Eosinophilic pneumonia ": 3.113102111251873, "Erysipelas ": 7.554391563057245, "Erythema nodosum ": 3.3863449711733127, "Erythrodermic psoriasis ": 47.99823248833443, "Escherichia urinary tract infection ": 2.1531959699189174, "Exposure during pregnancy ": 6.608454595008656, "Eye operation ": 2.238253465977187, "Faecal calprotectin ": 207.83064511139128, "Faecal calprotectin abnormal ": 120.084180795123, "Faecal calprotectin increased ": 25.701871949285337, "Fistula ": 31.488543362110903, "Fistula discharge ": 30.4405988832484, "Follicular lymphoma ": 7.292687689552457, "Foot operation ": 2.586664427906689, "Frequent bowel movements ": 3.614095293989173, "Furuncle ": 2.379078965461604, "Gallbladder operation ": 3.60637943280836, "Gastric cancer ": 2.1008916435810434, "Gastrointestinal carcinoma ": 2.739923497308524, "Gastrointestinal infection ": 3.727768642059204, "Gastrointestinal inflammation ": 3.315620923347393, "Gestational diabetes ": 2.0095745357204344, "Gingivitis ": 2.7356693109955748, "Glioblastoma ": 4.795264726169499, "Graves' disease ": 2.1790196192723497, "Guttate psoriasis ": 36.026738477223056, "HIV infection ": 6.786152554688027, "Haematochezia ": 3.0657996835981964, "Henoch-Schonlein purpura ": 2.8506316466668613, "Hepatic cirrhosis ": 2.728134725249486, "Hepatic steatosis ": 2.27106221744866, "Hepatitis B ": 2.38344385803842, "Hernia ": 5.810440246909886, "Herpes ophthalmic ": 2.918707663223381, "Herpes virus infection ": 3.8324399324179312, "Hidradenitis ": 6.703902584385763, "Hip surgery ": 2.9971319148639286, "Hodgkin's disease ": 6.94850986938331, "Human papilloma virus test positive ": 4.071880291253221, "Hysterectomy ": 5.71035751410505, "Idiopathic intracranial hypertension ": 2.6763360230973765, "IgA nephropathy ": 9.598885732283458, "Ileal stenosis ": 38.1496453799906, "Ileostomy ": 20.803512751705878, "Immunosuppression ": 2.873254307844572, "Impetigo ": 4.270597814197234, "Inappropriate schedule of product administration ": 7.030303408050163, "Incorrect dose administered ": 2.2632884017835764, "Incorrect route of product administration ": 2.516594297263296, "Infective spondylitis ": 17.41323762565731, "Infertility ": 3.4362253054291165, "Inflammatory bowel disease ": 13.420157442534055, "Infusion related reaction ": 6.866808505768802, "Intervertebral discitis ": 4.989373212359169, "Intestinal obstruction ": 7.975874668911324, "Intestinal operation ": 33.542110172196026, "Intestinal perforation ": 3.221121869111768, "Intestinal resection ": 36.60298156918995, "Intestinal stenosis ": 91.77072364467506, "Intestinal ulcer ": 4.220595513349275, "Intracranial aneurysm ": 2.792653939806947, "Intraductal proliferative breast lesion ": 7.059027030616733, "Invasive ductal breast carcinoma ": 3.4566542650126584, "Iron deficiency anaemia ": 2.88500398146181, "Joint noise ": 2.070339173151736, "Kidney infection ": 2.7069662444856606, "Knee arthroplasty ": 3.203501352058184, "Knee operation ": 5.823361416734164, "Large intestinal stenosis ": 21.046049191351887, "Large intestine perforation ": 2.1770731602451368, "Laryngeal cancer ": 9.670535321309991, "Latent tuberculosis ": 56.52300315935105, "Leukaemia ": 2.1177966329264737, "Limb operation ": 2.7093565402621667, "Lipoma ": 7.266525397216478, "Liquid product physical issue ": 5.76983259568185, "Loss of therapeutic response ": 52.34013902510119, "Lower respiratory tract infection ": 3.677432021359204, "Lung adenocarcinoma ": 9.394738266102213, "Lung cancer metastatic ": 4.489651987862212, "Lung neoplasm ": 3.1548024165754045, "Lung neoplasm malignant ": 2.9350670277153568, "Lupus-like syndrome ": 6.700268150139073, "Lyme disease ": 3.802317427090035, "Lymphocytosis ": 2.5500494780499463, "Lymphoma ": 5.056050739083417, "Malignant melanoma ": 8.22177690420082, "Malignant melanoma in situ ": 6.499803782123895, "Malnutrition ": 2.0192239115484565, "Mastitis ": 2.783530067193339, "Meningioma ": 3.267509000760177, "Meniscus injury ": 2.159682843530743, "Metabolic surgery ": 9.414893098362, "Metastatic squamous cell carcinoma ": 20.30149001189801, "Multiple sclerosis ": 2.551347505634536, "Mycobacterium tuberculosis complex test positive ": 54.70661375516564, "Myocardial infarction ": 2.5867038276028844, "Nail psoriasis ": 16.925933751935, "Needle issue ": 14.151751896262011, "Nephrolithiasis ": 2.9541414888518185, "Non-Hodgkin's lymphoma ": 3.069883371997933, "Off label use ": 6.021315777504968, "Oral infection ": 3.2720420714586163, "Osteitis ": 5.941926689676518, "Osteomyelitis ": 2.7519021333146845, "Otitis externa ": 5.734648203180128, "Palmoplantar pustulosis ": 12.212346205089586, "Pancreatitis relapsing ": 4.349670037640452, "Papilloma viral infection ": 10.148003900572236, "Paternal exposure during pregnancy ": 19.712343347763444, "Pemphigoid ": 2.347851611356385, "Periodontitis ": 7.815516190968091, "Peripheral artery thrombosis ": 2.295140996474106, "Pertussis ": 12.02394070185708, "Pharyngitis ": 2.339977142940845, "Pharyngitis streptococcal ": 2.592391030267944, "Pneumonia ": 2.0939515313756445, "Pneumonia legionella ": 6.840133106615349, "Pneumonia pneumococcal ": 3.69733247732768, "Poor quality product administered ": 4.608336841547685, "Posterior reversible encephalopathy syndrome ": 3.8796188806632, "Postoperative wound infection ": 4.089929510783841, "Pouchitis ": 28.60589190480127, "Precancerous skin lesion ": 8.80123540294716, "Pregnancy of partner ": 26.72668276872753, "Premature labour ": 3.057233923924256, "Proctocolectomy ": 63.96931646068537, "Product dose omission issue ": 9.537317791767652, "Product label issue ": 7.957760447998941, "Product leakage ": 3.318890499698033, "Product measured potency issue ": 7.045932267735833, "Product packaging issue ": 6.782418162370936, "Product packaging quantity issue ": 4.0151584796472095, "Product storage error ": 8.201716521915186, "Product use in unapproved indication ": 2.4833312958060216, "Product use issue ": 9.813735862874276, "Prostate cancer ": 6.871659265801518, "Prostate cancer metastatic ": 2.4072680104884103, "Psoriasis ": 45.92494760760212, "Psoriasis area severity index increased ": 97.88198677088477, "Psoriatic arthropathy ": 29.7299817903874, "Pustular psoriasis ": 41.76130811056303, "Pustule ": 2.5147368086316426, "Pyelonephritis ": 2.0191446390127448, "Pyoderma gangrenosum ": 16.05297493890653, "Rash pustular ": 3.182413094186707, "Rectal abscess ": 36.27013395390577, "Rectal adenocarcinoma ": 12.30189522109119, "Rectal cancer ": 10.4883039625451, "Renal mass ": 4.941227626071204, "Renal neoplasm ": 5.623926697634691, "Respiratory tract infection ": 3.6742421960699816, "Retained products of conception ": 8.556838414656077, "Rubber sensitivity ": 10.489393430444723, "Sacroiliitis ": 9.368177883226736, "Sarcoidosis ": 4.055611918109393, "Scar pain ": 8.75053224659397, "Short-bowel syndrome ": 22.62745626190997, "Shoulder operation ": 4.379247601871551, "Skin cancer ": 5.665972084085134, "Skin exfoliation ": 2.2518044513179927, "Skin infection ": 3.601260673925592, "Skin papilloma ": 4.004831047652977, "Skin plaque ": 2.625866186484655, "Small cell lung cancer ": 3.541532418394346, "Small intestinal obstruction ": 7.414550419634993, "Small intestinal perforation ": 4.4831553560990285, "Small intestinal resection ": 19.978112595099883, "Small intestinal stenosis ": 42.25839490229045, "Small intestine carcinoma ": 5.868201334005183, "Spinal fusion surgery ": 3.3247838865896604, "Spinal operation ": 3.3326781896760944, "Splenectomy ": 4.877480320874592, "Spondylitis ": 3.772376487167362, "Squamous cell carcinoma ": 13.270028462710686, "Squamous cell carcinoma of lung ": 11.694967648116554, "Squamous cell carcinoma of skin ": 5.230397285948582, "Staphylococcal bacteraemia ": 2.2548680041100884, "Staphylococcal infection ": 4.69020892587279, "Stenosis ": 9.353939235822224, "Streptococcal infection ": 5.952111671836829, "Subcutaneous abscess ": 5.217637143572428, "Subileus ": 6.204517686920676, "Surgery ": 8.179433416478334, "Syringe issue ": 71.35382302501024, "Systemic lupus erythematosus rash ": 3.639116816563101, "T-cell lymphoma ": 11.782439767724885, "Testis cancer ": 4.083491916500752, "Therapeutic product effect decreased ": 5.185790142698638, "Therapeutic product ineffective ": 5.091447313510626, "Therapeutic response decreased ": 14.964551820009689, "Therapeutic response shortened ": 5.224574648637132, "Therapy non-responder ": 5.081022335905902, "Thyroid cancer ": 5.294489618838656, "Tinea versicolour ": 15.929506415333057, "Tongue neoplasm malignant stage unspecified ": 8.10291956593776, "Tonsillitis ": 3.834665468510936, "Tooth abscess ": 10.34106619230676, "Tooth extraction ": 2.726978248761246, "Tooth infection ": 5.508861727600191, "Transitional cell carcinoma ": 21.44910115924472, "Treatment noncompliance ": 2.105287301714133, "Tuberculin test positive ": 59.56436814816962, "Tuberculosis ": 10.695655877914728, "Umbilical hernia ": 2.583810603874916, "Underdose ": 2.6275967751343385, "Upper respiratory tract infection ": 3.810089700823908, "Uterine cancer ": 3.277359316820671, "Vena cava thrombosis ": 3.4108698464370937, "Viral infection ": 3.2153666793620825, "Vitiligo ": 9.276179696745574, "Vulvovaginal mycotic infection ": 2.532104647644841, "Weight fluctuation ": 2.136139222542012, "Wrong dose ": 3.5124705460272687}
\ No newline at end of file
+{"Acromegaly": 1167.8586757180838, "Arterial occlusive disease": 61.40886252165932, "Blood cholesterol abnormal": 125.68558345530217, "Blood growth hormone increased": 1567.6136640463608, "Blood pressure increased": 2.6867497856468776, "Bradycardia": 8.070330517226365, "Cellulitis": 10.484020847367836, "Chest discomfort": 3.04205091747726, "Drug hypersensitivity": 6.223032204913022, "Drug intolerance": 7.66977011149899, "Fall": 2.4860273494299947, "Gait disturbance": 3.142575354991156, "Goitre": 97.82226335142823, "Heart rate decreased": 15.84040714212818, "Hypersensitivity": 4.052739252482582, "Inappropriate schedule of product administration": 7.913379590326489, "Incorrect route of product administration": 16.851669547281585, "Injection site bruising": 42.68564604487056, "Injection site oedema": 48.44739766612511, "Injection site pain": 2.163032452951404, "Insulin-like growth factor increased": 2152.5677485815067, "Limb injury": 28.849978134739857, "Peripheral swelling": 2.480743531082287, "Polyp": 126.81002671235574, "Pulmonary embolism": 5.5440660845432586, "Syringe issue": 158.79809861795198, "Tendonitis": 21.905398881491408, "Vital functions abnormal": 721.8178136516517, "Weight decreased": 2.1154762204860043, "Wound infection": 82.84083206435105}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1014.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1014.json
index 12aeac27c09..1e235d379a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1014.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1014.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.2231581024559484, "Haemorrhoids ": 13.823249904224234, "Oedema ": 5.473815044901856, "Sprue-like enteropathy ": 16.07254395745642}
\ No newline at end of file
+{"Intentional overdose": 36.05160301566608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1015.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1015.json
index 1ad68caed90..de523fb86ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1015.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1015.json
@@ -1 +1 @@
-{"Decreased appetite ": 15.524465486091248, "Hyperammonaemia ": 498.2714011121074}
\ No newline at end of file
+{"Alpha 1 foetoprotein increased": 117.58745308698218, "Ascites": 5.550053398271658, "Blister": 3.4120996548188627, "Diarrhoea": 3.3407404264033818, "Disease progression": 5.839117538334553, "Drug ineffective for unapproved indication": 6.258355117317848, "Erythema multiforme": 5.510979238909851, "Haematotoxicity": 11.741519357162655, "Hepatic encephalopathy": 10.293247755647284, "Hepatic failure": 6.0591430036270655, "Hepatocellular carcinoma": 45.14421136202953, "Hepatotoxicity": 5.478867204588851, "Hyperkeratosis": 18.3733643542266, "Hypertension": 3.013407366915988, "Hypocalcaemia": 9.6470695970997, "International normalised ratio increased": 2.1038195462158686, "Malignant neoplasm progression": 2.809789132493224, "Metastases to adrenals": 69.905760963194, "Metastases to bone": 8.459648334480317, "Metastases to liver": 6.502514645388471, "Metastases to lung": 30.543054872294285, "Metastatic renal cell carcinoma": 30.86796027671447, "Mucosal inflammation": 8.28979992726653, "Neoplasm progression": 3.452534897166229, "Off label use": 5.293977606675179, "Osteonecrosis of jaw": 14.70981260897226, "Palmar-plantar erythrodysaesthesia syndrome": 71.92652538146406, "Product use in unapproved indication": 7.835363440653246, "Rash maculo-papular": 2.776626436271433, "Renal cell carcinoma": 15.910019249109528, "Skin exfoliation": 2.8192660283382813, "Skin reaction": 4.758319618050393, "Skin toxicity": 48.99359915368554, "Skin ulcer": 6.50701368486814, "Squamous cell carcinoma of skin": 28.353003645537928, "Stevens-Johnson syndrome": 4.156051349482739, "Thrombocytopenia": 3.780902588912728, "Tumour lysis syndrome": 15.731632606322991, "Weight decreased": 2.306152531961974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1016.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1016.json
index 067755d012b..0e4f7676cb8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1016.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1016.json
@@ -1 +1 @@
-{"Abdominal abscess ": 4.218059667625735, "Acute hepatic failure ": 3.914022727578105, "Adenocarcinoma of colon ": 37.6148695725063, "Alanine aminotransferase increased ": 5.307689503512639, "Alpha 1 foetoprotein increased ": 8.002770564380778, "Ammonia increased ": 9.495013922609548, "Anal abscess ": 4.952402543059005, "Anal fistula ": 6.595486222015647, "Aphonia ": 2.55817137582958, "Ascites ": 7.269938269043571, "Aspartate aminotransferase increased ": 6.9644605263144, "Asthenia ": 2.4641126546249152, "Biliary obstruction ": 6.794278220510165, "Bilirubin conjugated increased ": 7.916564433898229, "Blister ": 4.34699061045532, "Blood albumin decreased ": 4.575094701203058, "Blood alkaline phosphatase increased ": 2.4160293558668413, "Blood bilirubin increased ": 18.143605970705973, "Blood lactate dehydrogenase increased ": 2.5588509426621973, "Blood pressure increased ": 2.583158091345232, "Blood thyroid stimulating hormone increased ": 5.465871739228595, "C-reactive protein increased ": 2.944054792195961, "Cachexia ": 3.156855688692747, "Cancer pain ": 17.15482893216877, "Carbohydrate antigen 19-9 increased ": 39.69305559320301, "Carcinoembryonic antigen increased ": 85.28076811996347, "Cardiac dysfunction ": 3.819022199562944, "Cell death ": 5.177619804681565, "Cholangitis ": 7.163498903841889, "Cholecystitis ": 3.506593248066369, "Chromaturia ": 3.289256791702419, "Colon cancer ": 63.01735440490184, "Colon cancer metastatic ": 91.76225954538565, "Colon cancer recurrent ": 131.97498990633417, "Colorectal cancer ": 20.789843672744063, "Colorectal cancer metastatic ": 409.7156699371501, "Colorectal cancer recurrent ": 325.45601586150894, "Colorectal cancer stage IV ": 94.30195652008835, "Coma hepatic ": 9.135235659397043, "Death ": 2.408789695133592, "Decreased appetite ": 3.940230375813604, "Dermatitis bullous ": 2.726403222348529, "Dermatitis exfoliative ": 3.8163338805428335, "Dermatitis exfoliative generalised ": 3.2921134231959983, "Diarrhoea ": 2.420094225011319, "Disease progression ": 2.331310623178662, "Disseminated intravascular coagulation ": 8.093017908698611, "Drug eruption ": 7.083534351605588, "Drug-induced liver injury ": 4.874893614331035, "Dry skin ": 2.1585553927001384, "Duodenal perforation ": 17.84452260203771, "Dysphonia ": 14.28653368540536, "Eastern Cooperative Oncology Group performance status worsened ": 9.22460950437574, "Eating disorder ": 2.40509063864275, "Erythema multiforme ": 13.90676315287218, "Faeces discoloured ": 2.045355825407793, "Gastrointestinal perforation ": 30.192403927791126, "Gastrointestinal stromal tumour ": 29.829892794878464, "General physical health deterioration ": 2.7473036898688576, "Gingival bleeding ": 2.2531532524976754, "Glossitis ": 2.8679538698210845, "Haemorrhage urinary tract ": 3.711476793133804, "Hepatic encephalopathy ": 16.78642664509995, "Hepatic failure ": 8.636632298966086, "Hepatic function abnormal ": 10.63835845570408, "Hepatic mass ": 5.137931716152903, "Hepatitis fulminant ": 7.0359841607686455, "Hepatocellular carcinoma ": 17.792609847090493, "Hepatotoxicity ": 5.156989869061184, "Hydronephrosis ": 4.055185546224528, "Hyperammonaemia ": 4.869945673019456, "Hyperbilirubinaemia ": 8.973271325476142, "Hyperkeratosis ": 21.792225227511054, "Hypertension ": 4.749046293897282, "Hyperthermia ": 2.5571918749185523, "Hypertransaminasaemia ": 2.8283745600621306, "Hypoalbuminaemia ": 5.612907304162706, "Hypocalcaemia ": 3.3513129373358432, "Hypophagia ": 2.9216083736855487, "Hypophosphataemia ": 5.704116111091675, "Hypoproteinaemia ": 6.983315686377209, "Hypothyroidism ": 4.873288170592558, "Ileus ": 5.109396343139419, "Intestinal haemorrhage ": 5.545258221650082, "Intestinal obstruction ": 3.6023502676312416, "Intestinal perforation ": 5.331124309140023, "Jaundice ": 7.761999048342339, "Jaundice cholestatic ": 4.1565007985323765, "Large intestine perforation ": 3.2184559359953058, "Liver disorder ": 6.031307863881112, "Liver function test abnormal ": 2.787069006118719, "Liver function test increased ": 4.644175037317708, "Liver injury ": 2.698425874431802, "Lower gastrointestinal haemorrhage ": 2.869987148046988, "Lymphadenopathy mediastinal ": 5.82610558980444, "Mediastinal mass ": 24.471039095289207, "Melaena ": 2.815867544417741, "Metastases to abdominal cavity ": 24.28542944959026, "Metastases to adrenals ": 14.871516198932746, "Metastases to bone ": 4.69540707373648, "Metastases to central nervous system ": 10.325037494890625, "Metastases to liver ": 23.874126517292257, "Metastases to lung ": 38.118732324234486, "Metastases to lymph nodes ": 14.775683567287034, "Metastases to pelvis ": 26.880117247900117, "Metastases to peritoneum ": 23.85734842534587, "Metastases to spine ": 3.727047530953574, "Metastasis ": 5.534298052188569, "Mouth ulceration ": 3.5164763401527064, "Mucosal disorder ": 3.035452100708784, "Mucosal inflammation ": 9.972290900157718, "Nephrotic syndrome ": 3.939537064570632, "Ocular icterus ": 8.2514143042709, "Off label use ": 6.924310047619652, "Oral mucosa erosion ": 5.666083055556985, "Oral pain ": 2.9663636300145666, "Pain of skin ": 10.981597830924182, "Palmar-plantar erythrodysaesthesia syndrome ": 108.34766489515604, "Palmoplantar keratoderma ": 19.616636582000588, "Paronychia ": 2.908198723791648, "Performance status decreased ": 3.938495428818477, "Peritonitis ": 4.713961807887195, "Physical deconditioning ": 2.156306249538904, "Plantar erythema ": 51.83478744048034, "Platelet count decreased ": 8.013341828541762, "Portal hypertension ": 3.245864818011414, "Posterior reversible encephalopathy syndrome ": 7.168029557811422, "Pre-existing condition improved ": 8.243145150574604, "Proctalgia ": 5.255582445562452, "Protein urine present ": 13.60207694931976, "Proteinuria ": 9.854963822550864, "Pulmonary cavitation ": 14.51458307726868, "Pulmonary mass ": 2.998664571389495, "Rash maculo-papular ": 2.8064116937230037, "Rash papular ": 2.395909623620382, "Rectal adenocarcinoma ": 49.00619672516794, "Rectal cancer ": 49.32310634570033, "Rectal cancer metastatic ": 113.54632127258456, "Retroperitoneal lymphadenopathy ": 16.280993968272302, "Secondary hypertension ": 25.820594936627167, "Skin disorder ": 2.6989420433026377, "Skin erosion ": 3.8239177110882583, "Skin exfoliation ": 9.657830387498988, "Skin fissures ": 14.26684554132523, "Skin induration ": 7.926535035729247, "Skin injury ": 3.837779109460167, "Skin reaction ": 2.5102875397970736, "Skin swelling ": 7.935948615628367, "Skin toxicity ": 22.72282414744539, "Skin ulcer ": 4.842441244134107, "Skin warm ": 2.887390944099752, "Skin weeping ": 12.210612125245008, "Small intestinal perforation ": 13.151896442518924, "Stevens-Johnson syndrome ": 2.54660755667294, "Stoma site haemorrhage ": 53.40505685373885, "Stomatitis ": 6.527626139106558, "Subileus ": 5.516226425844927, "Temperature intolerance ": 2.4642145382163694, "Terminal state ": 3.174351485649747, "Therapeutic product ineffective ": 3.411395627791608, "Thrombocytopenia ": 2.117580725006289, "Toxic skin eruption ": 2.683455399512715, "Transaminases increased ": 3.523237684197687, "Tumour haemorrhage ": 16.490273241596334, "Tumour marker increased ": 16.638654375736774, "Tumour necrosis ": 18.155347248931783, "Tumour pain ": 14.553877713781176, "Weight decreased ": 2.1320964262044164, "Yellow skin ": 3.511508633704869}
\ No newline at end of file
+{"Alanine aminotransferase increased": 10.805313105473848, "Aspartate aminotransferase increased": 9.902324177422711, "Blood bilirubin increased": 9.164748462552684, "Diarrhoea": 5.963941289679823, "Disease progression": 10.689063711986478, "Drug-induced liver injury": 10.625166862238151, "Hepatic enzyme increased": 5.34836961827246, "Hepatic function abnormal": 9.268010685628123, "Hepatotoxicity": 44.974335675532025, "Liver disorder": 6.937692081216955, "Liver function test increased": 17.2586945444678, "Lung adenocarcinoma": 136.47393837646254, "Lung neoplasm malignant": 12.518128619614066, "Non-small cell lung cancer": 917.6710243441228, "Non-small cell lung cancer metastatic": 2736.759079656651, "Off label use": 2.092671466661886, "Therapy partial responder": 73.56637711356981}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1017.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1017.json
index 8f56b57e53d..98ad3f1ad88 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1017.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1017.json
@@ -1 +1 @@
-{"Abortion induced ": 55.492594492243846, "Alanine aminotransferase increased ": 3.564923615819831, "Blood alkaline phosphatase increased ": 10.51552654387456, "Drug interaction ": 3.5488844248817992, "Gamma-glutamyltransferase increased ": 13.98440149259873, "Gynaecomastia ": 32.00288477148004, "Hepatic function abnormal ": 6.044500916883304, "Immune reconstitution inflammatory syndrome ": 50.74421148408263, "Insomnia ": 2.223301781918884, "Liver injury ": 11.968814558743084, "Overdose ": 2.905313149425483, "Platelet count decreased ": 2.614785858600858, "Pregnancy ": 36.640987519026496, "Pruritus ": 2.450197395109578, "Rash ": 6.467513327331513, "Suicide attempt ": 5.525759789595508, "Toxic skin eruption ": 23.007443378207885, "Transaminases increased ": 8.512141752935223}
\ No newline at end of file
+{"Altered state of consciousness": 2.024050394367631, "Ammonia increased": 7.394131877404162, "Anaemia": 8.55958588248953, "Ascites": 9.094616982559542, "Atrial septal defect": 6.304609474381127, "Autoimmune hepatitis": 4.34647692809549, "Blood bilirubin increased": 7.412695506256812, "Cerebral haemorrhage": 2.4261612946622457, "Cerebral infarction": 3.809744463535769, "Colitis ischaemic": 5.542067546483547, "Death": 2.0131114079317567, "Depression": 2.201360839632474, "Disseminated intravascular coagulation": 2.2543983797041407, "Drug ineffective": 9.32907426444314, "Genotype drug resistance test positive": 15.422815593871432, "Glomerular filtration rate decreased": 4.504709760160125, "Haematemesis": 3.0708755356390083, "Haemoglobin decreased": 8.082692589051026, "Haemolytic anaemia": 12.313385417004216, "Hepatic cancer": 14.629033122198743, "Hepatic cancer recurrent": 602.0039890255414, "Hepatic cirrhosis": 22.786745654044303, "Hepatic encephalopathy": 28.74600624895768, "Hepatic failure": 5.931417114939051, "Hepatic fibrosis": 12.041285487330828, "Hepatitis": 3.55365924842276, "Hepatitis B reactivation": 24.750836315201404, "Hepatitis C": 140.67988130454347, "Hepatitis C RNA increased": 76.9606002229754, "Hepatitis C RNA positive": 259.072465501785, "Hepatitis C virus test positive": 55.05430937726681, "Hepatocellular carcinoma": 48.2368636220552, "Hepatorenal syndrome": 16.059846038349804, "Hyperbilirubinaemia": 19.273544181611605, "Incorrect product administration duration": 6.3377282494176175, "Infection reactivation": 75.01193638089899, "Jaundice": 7.378857502671108, "Loss of consciousness": 2.441367856446145, "Lung neoplasm malignant": 2.0633085005915626, "Lymphoma": 6.231909913666382, "Mood swings": 2.400183233757752, "Multiple organ dysfunction syndrome": 2.8095887428918456, "Neoplasm malignant": 2.3829166882263846, "Oedema peripheral": 2.31561556491414, "Oesophageal varices haemorrhage": 38.12947358924573, "Pancreatitis acute": 2.857094945402418, "Photosensitivity reaction": 2.332324622538988, "Portal vein thrombosis": 15.421635932283817, "Product complaint": 2.159330908377829, "Renal impairment": 4.034343000103323, "Septic shock": 3.187501681052547, "Spontaneous bacterial peritonitis": 47.82313725936973, "Treatment failure": 15.409961112093988, "Treatment noncompliance": 3.1921722220004702, "Unevaluable event": 2.45048167784442, "Upper gastrointestinal haemorrhage": 2.0939908122346926, "Viral load increased": 23.913711484866848, "Virologic failure": 24.4060372416836}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1018.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1018.json
index 44fcb4425b0..0a782c3c02b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1018.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1018.json
@@ -1 +1 @@
-{"Acute kidney injury ": 3.837093010245585, "Adrenal suppression ": 6.897087185349649, "Anhedonia ": 37.93305612535252, "Ankle fracture ": 16.419407186686197, "Anxiety ": 9.74465712378995, "Blood HIV RNA increased ": 8.017341240353831, "Blood creatine increased ": 3.9269584221099176, "Blood creatinine abnormal ": 7.6005497975066785, "Blood creatinine increased ": 6.959423137482869, "Blood phosphorus decreased ": 3.7996629517840974, "Bone cyst ": 12.0161605234461, "Bone demineralisation ": 39.78471389191874, "Bone density abnormal ": 44.9800487963953, "Bone density decreased ": 41.367314904971614, "Bone disorder ": 9.567419231356164, "Bone loss ": 44.070120219291205, "CD4 lymphocytes decreased ": 7.833713108836502, "Cervical vertebral fracture ": 4.16721827273374, "Chronic kidney disease ": 29.96690061694021, "Chronic kidney disease-mineral and bone disorder ": 14.579060174187846, "Clavicle fracture ": 11.025723719402247, "Compression fracture ": 5.807050585340042, "Craniofacial fracture ": 5.086296515270692, "Decreased activity ": 8.72562595648275, "Degenerative bone disease ": 38.18806742020685, "Dental caries ": 4.099300429734812, "Depression ": 2.185897463030438, "Drug resistance ": 2.2244384333546305, "Dysstasia ": 4.08371184445533, "Economic problem ": 47.41659546093008, "Emotional distress ": 31.391290817044823, "End stage renal disease ": 13.156522103308722, "Fanconi syndrome ": 6.001312126304554, "Fanconi syndrome acquired ": 17.07001337853639, "Fear-related avoidance of activities ": 44.68238171689551, "Femur fracture ": 4.241734620439612, "Fibula fracture ": 11.484953535141832, "Foot fracture ": 13.093899613779907, "Fracture ": 24.913703256263304, "Fractured coccyx ": 7.70458096946798, "Gene mutation identification test positive ": 16.558650560064695, "Genotype drug resistance test positive ": 10.881243385437315, "Glomerular filtration rate abnormal ": 19.99977407824438, "Glomerular filtration rate decreased ": 7.059146965188791, "Glomerular filtration rate increased ": 11.120092820898366, "HIV test positive ": 8.126243426562583, "Hand fracture ": 22.89031908264416, "Hepatitis B ": 2.094615756278807, "Hip arthroplasty ": 6.665369088413817, "Hip fracture ": 5.156764603971011, "Hip surgery ": 3.8955786074570313, "Humerus fracture ": 3.2049474000090923, "Immune reconstitution inflammatory syndrome ": 3.661143387132785, "Impaired work ability ": 2.0435730049528598, "Intervertebral disc degeneration ": 6.914664223853307, "Jaw fracture ": 9.851149821781922, "Loss of personal independence in daily activities ": 2.9151883326726065, "Lower limb fracture ": 6.724854728671521, "Meniscus injury ": 2.8838998318480638, "Multiple fractures ": 39.76729575086082, "Nephrolithiasis ": 3.5586223456193964, "Nephropathy ": 14.935658524312323, "Nephropathy toxic ": 16.302223077865932, "Osteoarthritis ": 4.125715809934811, "Osteochondrosis ": 9.733075617096606, "Osteomalacia ": 15.30060678883252, "Osteonecrosis ": 40.16079280889993, "Osteopenia ": 31.278487027827527, "Osteoporosis ": 31.576430709141217, "Osteoporotic fracture ": 4.512159499609686, "Pain ": 4.357759529926079, "Patella fracture ": 4.065729447325782, "Pathological fracture ": 5.419408444349534, "Pelvic fracture ": 2.0078561174450296, "Post-traumatic stress disorder ": 4.149638767731106, "Protein total abnormal ": 38.08103452661691, "Protein total increased ": 16.158653148413833, "Protein urine present ": 12.203197917789748, "Proteinuria ": 4.7347056716076406, "Quality of life decreased ": 8.731561370371342, "Radius fracture ": 5.277221955770337, "Renal cyst ": 2.4887361267350983, "Renal failure ": 16.00421654754964, "Renal impairment ": 5.999427301353714, "Renal injury ": 25.85561510833812, "Renal tubular disorder ": 5.482068065821315, "Renal tubular dysfunction ": 5.2914957233283, "Renal tubular necrosis ": 2.957742685840929, "Rib fracture ": 12.038808566425972, "Shoulder fracture ": 7.770960339319937, "Skeletal injury ": 24.51679949132032, "Spinal compression fracture ": 8.189066809692145, "Spinal disorder ": 3.0617460029340062, "Spinal fracture ": 9.637133745949392, "Spinal osteoarthritis ": 8.63799507832165, "Spinal stenosis ": 3.0833051558831768, "Spondylolisthesis ": 11.455756623183191, "Stress fracture ": 8.399935519389151, "Teeth brittle ": 23.07609301873647, "Thoracic vertebral fracture ": 3.348862490082252, "Tibia fracture ": 10.712464721935309, "Toe amputation ": 2.4233715198134385, "Tooth disorder ": 3.680807680656984, "Tooth extraction ": 5.042597811637255, "Tooth fracture ": 21.65263019670649, "Tooth loss ": 36.9627791881238, "Ulna fracture ": 12.727599742554318, "Upper limb fracture ": 6.600377437949353, "Vertebral foraminal stenosis ": 22.88510668025476, "Viral load increased ": 9.588219359523416, "Viral mutation identified ": 7.4161622485859, "Virologic failure ": 8.415654762306158, "Vitamin D decreased ": 5.153770237075881, "Vitamin D deficiency ": 14.623116481880254, "Walking aid user ": 4.229195771901956, "Wrist fracture ": 12.41062327368115}
\ No newline at end of file
+{"Pancreatitis acute": 73.61796610087383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1019.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1019.json
index a7032860207..44a0450339b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1019.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1019.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 2.2618159254331727, "Abortion induced ": 10.19443815588424, "Abortion spontaneous ": 13.991029093548203, "Abscess limb ": 2.8444969163870018, "Accident ": 6.762251077999265, "Accident at work ": 9.39313332671235, "Accidental exposure to product ": 5.538641579097947, "Accidental exposure to product by child ": 51.65871949058116, "Accidental overdose ": 3.906873276587887, "Acute hepatitis C ": 29.492054904234347, "Adverse event ": 3.9337967290276574, "Affective disorder ": 2.5416264576307346, "Agitation neonatal ": 28.31337205127456, "Alcohol abuse ": 50.49009616089236, "Alcohol poisoning ": 2.788527834969622, "Alcohol withdrawal syndrome ": 13.518564500714602, "Alcoholism ": 13.524850524290496, "Amniotic cavity infection ": 11.133172099500111, "Amniotic fluid volume decreased ": 16.06592616913447, "Anaemia of pregnancy ": 94.80725815708314, "Anger ": 2.001304033547267, "Ankle fracture ": 3.0494537728361064, "Anxiety ": 2.198388937451164, "Appendicitis perforated ": 4.789270370465714, "Appendix disorder ": 15.236042885069162, "Arteritis ": 8.111207336119344, "Arthritis infective ": 2.492953101578481, "Attention deficit hyperactivity disorder ": 5.869074442857228, "Back disorder ": 4.939207972895123, "Back injury ": 2.531594537928948, "Behaviour disorder ": 2.2193967604555214, "Bipolar disorder ": 2.6546823123268464, "Blood testosterone decreased ": 7.850343356141138, "Borderline personality disorder ": 17.019392289535624, "Bradycardia foetal ": 4.459945284497608, "Brain injury ": 5.360301285658602, "Cardiac hypertrophy ": 6.242580803751714, "Cerebral disorder ": 3.3886342689814013, "Child neglect ": 116.90234484220994, "Cleft palate ": 2.6079772756504678, "Complication of pregnancy ": 12.302430305654587, "Concussion ": 3.867238544252468, "Congenital anomaly ": 3.179312330708469, "Craniocerebral injury ": 3.0883414613299, "Craniofacial fracture ": 7.370287345637366, "Crying ": 3.0007681073791224, "Dental caries ": 12.260898337107454, "Dependence ": 8.948206636483034, "Depression ": 2.891214143922844, "Detoxification ": 86.21226043552073, "Developmental delay ": 7.5887846433116035, "Developmental hip dysplasia ": 7.320469795924347, "Disability ": 4.5035243525296735, "Drug abuse ": 12.366158419340175, "Drug dependence ": 19.692413235083755, "Drug detoxification ": 391.7403601354425, "Drug diversion ": 58.92824727539924, "Drug effect less than expected ": 12.662908831845307, "Drug ineffective for unapproved indication ": 3.074502447124595, "Drug level fluctuating ": 12.910016547344798, "Drug screen negative ": 237.64494611689344, "Drug screen positive ": 31.266184512179965, "Drug withdrawal convulsions ": 5.4319396963362045, "Drug withdrawal syndrome ": 61.85913836699042, "Drug withdrawal syndrome neonatal ": 141.42806566129036, "Ectopic pregnancy ": 3.814897695120031, "Endocarditis ": 7.490375344788055, "Energy increased ": 8.18318350101582, "Euphoric mood ": 17.90177387073759, "Exposure during pregnancy ": 10.919754816910489, "Exposure via breast milk ": 54.04176509899519, "Extra dose administered ": 3.010074914349392, "Facial asymmetry ": 6.600815970740218, "Failure to thrive ": 5.414494186369426, "Feeling abnormal ": 2.818154086039913, "Feeling guilty ": 12.73339407539762, "Feeling jittery ": 2.551363903372269, "Feeling of body temperature change ": 5.806415910841904, "Feeling of despair ": 2.1918392229118457, "Fever neonatal ": 41.47779598071291, "Fibula fracture ": 5.898135360144878, "Foaming at mouth ": 3.3301114786820745, "Foetal distress syndrome ": 7.343852159233719, "Foetal exposure during pregnancy ": 24.32588940036343, "Foetal exposure via father ": 88.02238582520994, "Foetal growth restriction ": 6.465238408055325, "Foetal heart rate abnormal ": 7.182697200470504, "Foetal heart rate decreased ": 15.168320654258768, "Foetal hypokinesia ": 18.151206365298155, "Foot fracture ": 2.932384946720534, "Formication ": 2.823693538096489, "Gallbladder disorder ": 6.179491686137548, "Gestational diabetes ": 6.122639796010629, "Gestational hypertension ": 16.515077802070053, "Gingival disorder ": 2.8142363035856834, "Gun shot wound ": 37.69069877343805, "Hallucination ": 3.2101557455328, "Hallucination, auditory ": 4.223326806788521, "Hallucination, visual ": 2.739589857014244, "Hand fracture ": 3.003159636396897, "Head circumference abnormal ": 40.79234403401701, "Head injury ": 2.8684215703256477, "Heart disease congenital ": 3.2647461915389453, "Hepatic pain ": 3.45016794808575, "Hepatitis C ": 6.472613655317582, "High risk pregnancy ": 51.08161035876591, "Homicidal ideation ": 5.45277601633491, "Homicide ": 14.88869583374211, "Hospitalisation ": 5.327027265971126, "Hyperbilirubinaemia neonatal ": 16.18633658084823, "Hypertensive heart disease ": 3.593834878557539, "Hypoglycaemia neonatal ": 7.794614060569295, "Hypopnoea ": 2.940634881613922, "Illness ": 2.0168370197313, "Impaired driving ability ": 9.261469779098787, "Inadequate analgesia ": 8.553593895333734, "Inappropriate schedule of product administration ": 4.8563861509507165, "Inappropriate schedule of product discontinuation ": 170.14412666027445, "Incoherent ": 2.9157113473327385, "Incorrect route of product administration ": 2.0722922078997, "Infantile colic ": 175.21427846357096, "Infantile diarrhoea ": 68.77461683192561, "Infantile vomiting ": 17.59611855607073, "Injection site abscess ": 4.1172953446477125, "Injection site necrosis ": 3.434426479284284, "Insomnia ": 2.4162344840547383, "Intentional product misuse ": 6.23324655309875, "Intentional product use issue ": 5.534120197679731, "Intentional underdose ": 213.1942893543241, "Intervertebral disc degeneration ": 2.79680672844321, "Intervertebral disc disorder ": 3.107095275133679, "Intervertebral disc protrusion ": 3.641917602034987, "Irritability ": 2.823047324388566, "Jaundice neonatal ": 80.40969868606038, "Jaw fracture ": 5.824291756266206, "Joint injury ": 4.029814938029937, "Knee deformity ": 7.416733049002116, "Learning disability ": 17.16042433368738, "Libido decreased ": 3.742848708553416, "Ligament rupture ": 3.6305018078054094, "Limb crushing injury ": 19.798595992301724, "Limb injury ": 3.5477221890592454, "Lip and/or oral cavity cancer ": 12.683690788368708, "Loss of consciousness ": 2.6181734510103905, "Loss of employment ": 3.0588946057884714, "Low birth weight baby ": 20.40497803523439, "Lower limb fracture ": 3.7592135729671607, "Macrosomia ": 28.744040016204508, "Major depression ": 4.834075089151133, "Maternal exposure during pregnancy ": 8.588988252791335, "Meconium aspiration syndrome ": 62.304379222774536, "Meconium stain ": 33.18421055559569, "Medical observation ": 60.93715936813632, "Mental disorder ": 4.072375292129225, "Mental impairment ": 2.211182242728886, "Miosis ": 4.720773098128257, "Multiple cardiac defects ": 62.22198879561816, "Multiple congenital abnormalities ": 3.3340712938529053, "Nasal septal operation ": 86.29629797653344, "Neck injury ": 8.733726617050294, "Neonatal aspiration ": 55.03731513097423, "Neonatal disorder ": 48.67233379313334, "Neonatal respiratory distress ": 10.414938221429606, "Neonatal respiratory distress syndrome ": 10.154605265176643, "Neonatal seizure ": 20.166080255628472, "Nerve compression ": 4.503181881133476, "Nerve injury ": 2.3013412585414783, "No adverse event ": 2.31914639388907, "Ocular icterus ": 2.544180016405388, "Oligohydramnios ": 6.366391662804304, "Oral administration complication ": 64.07084743437848, "Ovarian cyst ": 2.2388025567298446, "Overdose ": 6.698285804535434, "Overweight ": 4.170635175804756, "Pain threshold decreased ": 165.49235665667692, "Pancreatitis chronic ": 2.418093236825073, "Panic attack ": 2.888701964811584, "Paranoia ": 7.139983385440125, "Paternal exposure during pregnancy ": 14.783800191642344, "Personal relationship issue ": 8.724636866096482, "Pharyngeal swelling ": 4.073912171359331, "Physical assault ": 8.063064019118448, "Piloerection ": 5.516033533357287, "Placenta praevia ": 21.271682447714632, "Poor feeding infant ": 26.64074560396661, "Poor sucking reflex ": 12.63857689910646, "Poor weight gain neonatal ": 76.55170159965064, "Post-traumatic stress disorder ": 5.350668358966052, "Postpartum haemorrhage ": 8.780587660818588, "Pre-eclampsia ": 10.713493428717651, "Pre-existing condition improved ": 3.794749168221852, "Premature baby ": 12.613000020992567, "Premature delivery ": 25.877519891624942, "Premature labour ": 24.61777763860196, "Premature rupture of membranes ": 8.098585419617384, "Premature separation of placenta ": 13.2070798210606, "Prescribed overdose ": 4.142747720913503, "Priapism ": 2.088614001504605, "Procedural pain ": 13.970137844451523, "Product dose omission in error ": 2.003271093613406, "Product preparation issue ": 321.30788190891906, "Product prescribing error ": 2.250476900541265, "Product use issue ": 3.362953270498493, "Psychomotor hyperactivity ": 4.9783731932162, "Psychotic disorder ": 2.4896395243094345, "Psychotic symptom ": 5.134825334271083, "Reading disorder ": 10.204851545877334, "Respiratory arrest ": 2.0044390897639754, "Respiratory depression ": 6.122183007716353, "Respiratory disorder neonatal ": 10.604916589382992, "Respiratory rate decreased ": 2.082497981554748, "Restless legs syndrome ": 2.4327105004168503, "Restlessness ": 2.5986642384327245, "Rib fracture ": 5.800062484734363, "Road traffic accident ": 14.882866851881028, "Seizure ": 2.557549528832165, "Selective abortion ": 65.30446761546476, "Selective eating disorder ": 40.35833863116071, "Shoulder fracture ": 2.1392611528795573, "Skin laceration ": 2.763378487992594, "Skull fracture ": 8.290320352565123, "Sleep apnoea syndrome ": 4.189922175011117, "Small for dates baby ": 8.649421186201847, "Sneezing ": 3.5518551041099613, "Social anxiety disorder ": 7.535644460978017, "Speech disorder developmental ": 6.975176944509329, "Spinal fracture ": 3.165319355364661, "Stillbirth ": 6.489649232193317, "Substance abuse ": 110.84615354209828, "Substance dependence ": 9.866326745740343, "Substance use disorder ": 8.271369941646682, "Sudden infant death syndrome ": 15.345675311234537, "Suicidal behaviour ": 2.6262076740942746, "Suicidal ideation ": 5.37430902588306, "Swollen tongue ": 2.311872305778017, "Tachyphrenia ": 7.393156670914466, "Talipes ": 3.210260962316968, "Testis cancer ": 3.0007010654876933, "Tethered oral tissue ": 22.257280058813027, "Theft ": 26.8826614579872, "Therapeutic product ineffective ": 18.095778640363644, "Therapeutic response unexpected ": 5.337789109114392, "Therapy interrupted ": 14.149536247408417, "Therapy naive ": 241.75796663131783, "Throat cancer ": 3.469265011896315, "Tibia fracture ": 3.257820204701702, "Tooth disorder ": 5.24044406874836, "Tooth erosion ": 14.6707835340572, "Tooth fracture ": 3.708419634774249, "Toothache ": 2.4500764260056265, "Toxicity to various agents ": 4.15242501818528, "Transient tachypnoea of the newborn ": 15.912317491591375, "Tremor neonatal ": 75.99515447246044, "Trisomy 21 ": 6.759020323081387, "Umbilical cord abnormality ": 14.445086620257037, "Underdose ": 11.486931876349562, "Unevaluable event ": 3.33812182149973, "Unresponsive to stimuli ": 4.271070394690093, "Upper limb fracture ": 4.540865846237788, "Uterine disorder ": 16.9348419921784, "Victim of abuse ": 65.32206147932757, "Victim of crime ": 76.69416857038044, "Victim of sexual abuse ": 36.7926682516745, "Vomiting projectile ": 5.692490690362532, "Vulvovaginal candidiasis ": 2.483180403894271, "Weight decrease neonatal ": 72.53984025747019, "Withdrawal syndrome ": 7.576035229295479, "Wrist fracture ": 2.8038879955139118, "Wrong technique in product usage process ": 8.221412740242723, "Yawning ": 9.518967689817346}
\ No newline at end of file
+{"Abnormal menstrual clots": 3.478635973324953, "Adenovirus test": 21.47579472376663, "Administration site erythema": 2.0893422325320654, "Administration site lymphadenopathy": 6.470529799971942, "Administration site movement impairment": 3.3853599431191803, "Administration site pruritus": 2.0238251489453227, "Administration site rash": 2.7510707571721262, "Administration site warmth": 3.7041973301947047, "Adnexa uteri pain": 2.3977203733597774, "Alanine aminotransferase normal": 35.034519208316254, "Allergy to vaccine": 2.121293836070407, "Angiogram": 2.1608260134199724, "Angiogram pulmonary abnormal": 30.463875443970583, "Anion gap": 4.3863425035514005, "Anticoagulant therapy": 4.801049691437267, "Application site movement impairment": 2.4071832046584767, "Application site reaction": 2.3882138687445185, "Application site swelling": 3.126222973815848, "Arthralgia": 2.443638661371368, "Aspartate aminotransferase normal": 28.53033660629104, "Axillary mass": 3.716606852044058, "Axillary pain": 4.544652974091021, "Bacille Calmette-Guerin scar reactivation": 7.585121110168986, "Basophil percentage decreased": 4.137830142011464, "Bell's palsy": 2.7323480043214343, "Blood alkaline phosphatase normal": 39.2133480753029, "Blood bilirubin normal": 52.109412659634685, "Blood calcium normal": 18.937175715182267, "Blood chloride normal": 36.8236670946199, "Blood creatinine normal": 34.88831879106123, "Blood culture": 11.38204589021447, "Blood culture negative": 2.640373705198257, "Blood glucose normal": 8.488734274519185, "Blood lactic acid": 3.586126415458252, "Blood potassium normal": 45.89665018291424, "Blood sodium normal": 37.66632364261925, "Blood test": 13.494651373392143, "Blood test normal": 27.287242905205744, "Blood urea normal": 35.02909825914515, "Body temperature abnormal": 2.0117305557644523, "Body temperature increased": 2.781323616490092, "Breakthrough COVID-19": 14.009407412121917, "Breast engorgement": 2.017499926551316, "COVID-19 immunisation": 16.61900265116591, "COVID-19 pneumonia": 2.255932866562324, "Carbon dioxide normal": 24.28435341930962, "Cardiac discomfort": 3.550092927489277, "Cardiac monitoring": 3.478635973324953, "Cardiac stress test": 5.980968731869647, "Chest X-ray": 20.07808162052106, "Chest X-ray normal": 46.13848117049877, "Chills": 3.945686995995882, "Computerised tomogram": 24.09456695083029, "Computerised tomogram abdomen abnormal": 8.929550944354656, "Computerised tomogram head": 5.431295484531295, "Computerised tomogram head abnormal": 9.19864459813618, "Computerised tomogram head normal": 28.474135998060078, "Computerised tomogram normal": 7.802456915609422, "Computerised tomogram thorax": 6.508839409482139, "Computerised tomogram thorax abnormal": 6.101362252824369, "Computerised tomogram thorax normal": 28.53033660629104, "Delirium febrile": 2.7050102831812604, "Dermal filler reaction": 8.046009948699199, "Diaphragmalgia": 2.1135581806443864, "Differential white blood cell count": 28.18024942030929, "Dysmenorrhoea": 2.4592894067738795, "Ear inflammation": 2.6224588293820084, "Echocardiogram": 19.286721630531325, "Echocardiogram abnormal": 2.54278772922082, "Echocardiogram normal": 22.567089862596283, "Ejection fraction normal": 33.24078679367958, "Electrocardiogram": 14.763826789662522, "Electrocardiogram normal": 17.256580365617623, "Electroencephalogram": 3.542602887455461, "Exercise tolerance decreased": 2.069156505426191, "Exposure to SARS-CoV-2": 4.558470857228003, "Extensive swelling of vaccinated limb": 11.729198809630306, "Eye infarction": 2.6120842747459743, "Facial discomfort": 2.032793693090156, "Fatigue": 2.716831608670772, "Feeling hot": 3.1671436873062917, "Fibrin D dimer": 12.5355319724461, "Full blood count": 12.69405066806334, "Full blood count normal": 9.162685007412223, "Glomerular filtration rate normal": 16.23246180124599, "Growing pains": 3.127311648742324, "Haematocrit normal": 20.452212841830843, "Haemoglobin normal": 16.975956652032924, "Headache": 2.592351406280922, "Heart rate": 2.496412280214256, "Heavy menstrual bleeding": 2.4727271822255936, "Hypomenorrhoea": 2.143189856438795, "Immediate post-injection reaction": 10.121738155634183, "Immunisation reaction": 4.871591331114365, "Immunoglobulin therapy": 4.245074883332947, "Impaired work ability": 2.0092771518911525, "Influenza": 3.3400541271201885, "Influenza A virus test negative": 28.77409830629225, "Influenza B virus test": 27.86046440444297, "Influenza like illness": 2.0606921000452614, "Influenza virus test negative": 10.432885952215912, "Injected limb mobility decreased": 4.637354806222072, "Injection site discomfort": 3.039565147383256, "Injection site erythema": 8.588257047045724, "Injection site haematoma": 4.827749771231789, "Injection site hypersensitivity": 2.695291636906402, "Injection site hypoaesthesia": 2.261289415382543, "Injection site induration": 8.539854820767324, "Injection site inflammation": 10.04311151245854, "Injection site joint movement impairment": 2.97726139593493, "Injection site lymphadenopathy": 3.4593882654886223, "Injection site macule": 2.2229872512204167, "Injection site movement impairment": 4.5477537080392665, "Injection site muscle weakness": 2.9569596923600248, "Injection site oedema": 2.061423246041963, "Injection site pain": 5.884784327337798, "Injection site paraesthesia": 2.544697704978642, "Injection site pruritus": 9.104677167805544, "Injection site rash": 2.978325004845822, "Injection site reaction": 4.053459073078722, "Injection site swelling": 9.29302841216401, "Injection site warmth": 11.313390044248282, "Inner ear inflammation": 2.502296931125042, "Intensive care": 3.451844079261878, "Interchange of vaccine products": 2.578317306784124, "Intermenstrual bleeding": 2.430339405368759, "Laboratory test": 34.842175210949605, "Laboratory test normal": 12.19525419628571, "Limb discomfort": 4.76640872556863, "Local reaction": 3.332324887716945, "Lymph node pain": 3.1556327160657536, "Lymphadenopathy": 3.739810067598645, "Magnetic resonance imaging": 16.08806745865082, "Magnetic resonance imaging head": 3.915891187093, "Magnetic resonance imaging head normal": 15.550590747291748, "Magnetic resonance imaging heart": 6.624853611126119, "Magnetic resonance imaging normal": 11.323023439499815, "Malaise": 3.1412795476932174, "Maternal exposure during breast feeding": 2.5705593562706834, "Mechanical urticaria": 9.001892321218055, "Menometrorrhagia": 2.3831760073212056, "Menstrual cycle management": 2.451935947999842, "Menstrual discomfort": 2.691128157365338, "Menstrual disorder": 2.785343021766827, "Menstruation delayed": 2.149235441258273, "Menstruation irregular": 2.684526504083049, "Metabolic function test": 38.01847077053611, "Metabolic function test normal": 11.323023439499815, "Multisystem inflammatory syndrome": 2.150816462113289, "Multisystem inflammatory syndrome in adults": 2.5616964390696686, "Muscle swelling": 2.862222693521663, "Myalgia": 3.4788886831647923, "Myelin oligodendrocyte glycoprotein antibody-associated disease": 2.570001093044296, "Myocarditis": 3.291475245389768, "Myopericarditis": 4.95952318993707, "Nasal herpes": 2.493744301010687, "Neuralgic amyotrophy": 2.984415024784666, "New daily persistent headache": 3.4410963469721625, "Oligomenorrhoea": 2.5391486020275877, "Ovulation pain": 2.470108668783436, "Pain in extremity": 2.224113361117952, "Painful respiration": 2.283196275860032, "Platelet count normal": 13.57034448414263, "Polymenorrhoea": 2.8071751561424243, "Positive airway pressure therapy": 4.209914209644631, "Post vaccination syndrome": 2.5718315906901013, "Post-acute COVID-19 syndrome": 2.269776931213781, "Postmenopausal haemorrhage": 2.5693829418963903, "Premenstrual pain": 2.5743712548674136, "Premenstrual syndrome": 2.1064536601124577, "Presyncope": 2.5155029723572717, "Procalcitonin": 19.25478310735708, "Pulmonary pain": 2.2230210246420308, "Puncture site erythema": 2.9844699880524823, "Puncture site oedema": 2.202286113585584, "Puncture site pain": 2.123557960909207, "Puncture site pruritus": 2.7029194172027804, "Puncture site reaction": 4.2626844448210806, "Puncture site swelling": 2.3260495576509728, "Pyrexia": 2.6807157208460213, "Respiratory syncytial virus test negative": 7.837596646279589, "Rest regimen": 3.192804128051728, "SARS-CoV-2 antibody test negative": 2.115360732458852, "SARS-CoV-2 test": 2.680299963082656, "SARS-CoV-2 test positive": 2.9114461030813183, "Scan with contrast abnormal": 13.059603711369263, "Sick leave": 3.4800383488956026, "Skin warm": 2.1369045543592877, "Specialist consultation": 2.004243445077013, "Tenderness": 2.418596080556039, "Thrombectomy": 2.097386340285113, "Thyroiditis subacute": 2.0152795749285035, "Tinnitus": 2.060643594255768, "Trichodynia": 2.7029194172027804, "Troponin": 10.009676916295998, "Troponin I": 5.658868087956544, "Troponin normal": 40.31283568566023, "Ultrasound Doppler": 9.211026915418229, "Ultrasound Doppler abnormal": 5.135740375057393, "Ultrasound scan": 17.97962747500936, "Urine analysis": 21.26085129117077, "Urine analysis normal": 9.932330184936642, "Urticaria chronic": 6.48450616608554, "Urticaria physical": 3.762240226695949, "Uterine pain": 2.148445097897425, "Vaccination complication": 2.7513574196908603, "Vaccination site anaesthesia": 3.3905194389852964, "Vaccination site bruising": 2.948621457100035, "Vaccination site coldness": 2.130150629721304, "Vaccination site dermatitis": 2.469002257878272, "Vaccination site discharge": 2.8373615110011308, "Vaccination site discolouration": 3.8329782106008192, "Vaccination site discomfort": 3.581414604118077, "Vaccination site dysaesthesia": 3.098855753053404, "Vaccination site eczema": 2.1560321186073264, "Vaccination site erythema": 9.48038970395938, "Vaccination site exfoliation": 3.762240226695949, "Vaccination site haematoma": 2.2955020473997525, "Vaccination site haemorrhage": 2.480874280352384, "Vaccination site hyperaesthesia": 5.340100465051638, "Vaccination site hypersensitivity": 3.172077340616561, "Vaccination site induration": 4.357639986696224, "Vaccination site infection": 5.793759033163043, "Vaccination site inflammation": 4.049259034197164, "Vaccination site irritation": 4.433093113123713, "Vaccination site joint erythema": 5.053459614222733, "Vaccination site joint movement impairment": 2.941504048812252, "Vaccination site joint pain": 2.888851514119865, "Vaccination site joint swelling": 5.130882669767635, "Vaccination site joint warmth": 4.27980290036856, "Vaccination site lymphadenopathy": 4.449248712217094, "Vaccination site macule": 14.482614676282225, "Vaccination site mass": 2.217498772266236, "Vaccination site movement impairment": 5.574206071555064, "Vaccination site oedema": 4.693628928080684, "Vaccination site pain": 3.60540702191016, "Vaccination site papule": 2.3222269398945103, "Vaccination site paraesthesia": 2.191809999881306, "Vaccination site plaque": 16.57793478548532, "Vaccination site pruritus": 9.183138287206155, "Vaccination site pustule": 3.3717636925206103, "Vaccination site rash": 12.813142234509296, "Vaccination site reaction": 8.126575220960033, "Vaccination site swelling": 7.08153072532756, "Vaccination site urticaria": 9.844205031402227, "Vaccination site vesicles": 2.276433878826524, "Vaccination site warmth": 8.86583638026166, "Vaccine breakthrough infection": 14.188453718405372, "Vaccine positive rechallenge": 4.030741665472295, "Weight bearing difficulty": 3.023862449248031, "White blood cell count normal": 29.923361968674733, "X-ray": 21.26085129117077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/102.json
index f8aee1398d8..4247d82ba18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/102.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 11.366995864393528, "Alopecia ": 11.53889758522827, "Anti-cyclic citrullinated peptide antibody ": 18.884061263319705, "Anti-cyclic citrullinated peptide antibody positive ": 55.833767501792, "Arthropathy ": 21.884931133281384, "Atelectasis ": 27.950465274634503, "Autoimmune disorder ": 8.58288867959757, "Barrett's oesophagus ": 72.22825313802474, "Blister ": 20.85342885254644, "Blood cholesterol increased ": 3.198187677916212, "Bursitis ": 6.845969820040452, "C-reactive protein abnormal ": 8.214585091180096, "Computerised tomogram thorax ": 490.7821148960112, "Computerised tomogram thorax abnormal ": 127.24802931445866, "Condition aggravated ": 6.533140997070747, "Confusional state ": 8.304303866771997, "Contraindicated product administered ": 19.48181001863859, "Contusion ": 17.2122099043093, "Deep vein thrombosis postoperative ": 27.82150165726569, "Discomfort ": 22.677592482980696, "Drug hypersensitivity ": 2.810212022339558, "Drug intolerance ": 7.682090277745229, "Duodenal ulcer perforation ": 90.4668098392763, "Dyspepsia ": 2.4009209694429616, "Dyspnoea ": 2.645207755199389, "Erosive oesophagitis ": 194.66640392393444, "Eructation ": 14.993387411042413, "Facet joint syndrome ": 9.568040256098945, "Folliculitis ": 67.6329721027273, "Gastrointestinal disorder ": 21.184427968686084, "General physical health deterioration ": 12.675750125958908, "Glossodynia ": 31.26092587474628, "Haematemesis ": 7.128921403952469, "Haematoma ": 2.2415298008861395, "Hand deformity ": 45.12003483895201, "Helicobacter infection ": 82.99315107728042, "Hepatic enzyme increased ": 16.99299136086368, "Hypersensitivity ": 8.025801396188982, "Hypoxia ": 3.6506345400712936, "Ill-defined disorder ": 36.56523764826924, "Impaired healing ": 50.58495734397461, "Infection ": 12.10962647505432, "Infusion related reaction ": 19.524010325729176, "Injury ": 17.91978046365896, "Irritable bowel syndrome ": 12.84806847105128, "Lower respiratory tract infection ": 3.8057202539450303, "Muscle injury ": 10.68946862316932, "Oesophageal haemorrhage ": 221.55515272500247, "Oesophageal mucosal dissection ": 3985.207007354716, "Oropharyngeal discomfort ": 10.805707007532696, "Regurgitation ": 58.52446894248711, "Respiratory syncytial virus infection ": 11.862777383961882, "Vitamin B12 deficiency ": 48.45176838222381}
\ No newline at end of file
+{"Accidental overdose": 2.167505600030016, "Adverse reaction": 2.8796795346480057, "Altered state of consciousness": 2.3255643928279883, "Anti-insulin antibody increased": 59.32902051324072, "Anti-insulin antibody positive": 85.91391116760417, "Arterial occlusive disease": 7.867201110321627, "Bladder disorder": 2.336219350721648, "Blindness": 2.9443070747320896, "Blindness unilateral": 6.0071435062116, "Blood glucose abnormal": 31.088032140875683, "Blood glucose decreased": 23.33990383947555, "Blood glucose fluctuation": 35.04649213141235, "Blood glucose increased": 22.67842091984605, "Blood immunoglobulin E increased": 2.7055591818698197, "Blood testosterone decreased": 4.174462589308704, "Body mass index decreased": 19.289516663745637, "Breast mass": 2.9421917405949385, "Cardiac operation": 2.707573804689044, "Cataract": 5.56654018953342, "Cataract operation": 4.740773584144844, "Cataract subcapsular": 27.85756004649461, "Circumstance or information capable of leading to medication 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4.110255914640782, "Drug dose omission by device": 5.867084425452588, "Drug ineffective": 2.0239825799180298, "Episcleritis": 20.25030887523095, "Expired device used": 22.92441018192392, "Expired product administered": 14.901815873537812, "Exposure during pregnancy": 3.5262143672376656, "Exposure via breast milk": 4.679269679611808, "Extra dose administered": 7.199423882958384, "Eye disorder": 2.022267112237173, "Eye haemorrhage": 4.1372166223921925, "Feeding disorder": 2.200229058672741, "Foetal death": 2.651402355361708, "Foetal exposure timing unspecified": 31.99287144806591, "Foot fracture": 2.231101418993607, "Glaucoma": 2.3696678315432447, "Glycosylated haemoglobin increased": 18.33535461941884, "Haemodialysis": 4.39895567956903, "Hospitalisation": 2.695315416351243, "Hunger": 10.08146442601987, "Hyperglycaemia": 46.02668627317476, "Hyperhidrosis": 2.608895210305412, "Hyperinsulinaemic hypoglycaemia": 69.58660120169772, "Hyperphagia": 6.447837286969352, "Hypoglycaemia": 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2.426964802831161, "Injection site nodule": 7.26497215940671, "Injection site oedema": 3.332276190692532, "Injection site urticaria": 4.612125939517751, "Insulin resistance": 9.378273716821695, "Intentional product misuse": 2.351196010934683, "Intestinal haemorrhage": 3.230927868661144, "Ketoacidosis": 11.670945466137614, "Ketonuria": 9.114095038352255, "Ketosis": 10.536843631695382, "Kidney infection": 2.047087640104844, "Leg amputation": 4.660191677880037, "Limb operation": 5.10078810327346, "Lipoatrophy": 7.125144725168804, "Lipodystrophy acquired": 16.59811482947804, "Liquid product physical issue": 7.734987887301941, "Localised infection": 3.83754297624723, "Loss of consciousness": 3.916156264693912, "Macular degeneration": 2.005575093212148, "Macular oedema": 8.015776975602865, "Maternal exposure timing unspecified": 2.69748232895517, "Medication error": 7.344471611848577, "Multiple lentigines syndrome": 366.73590227594497, "Multiple use of single-use product": 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"Retinopathy": 8.403072881468624, "Road traffic accident": 2.489814026548944, "Shock hypoglycaemic": 20.10457803489036, "Sopor": 16.182754782088264, "Substance use": 12.852154290783206, "Tendon disorder": 2.7634852465380204, "Therapeutic product effect delayed": 6.612883497172784, "Therapeutic response decreased": 2.5784233596194137, "Thermal burn": 4.782162122879303, "Thirst": 3.539781854397194, "Tinea infection": 28.1183835003678, "Tinea pedis": 16.42877489697499, "Toe amputation": 7.770620426632562, "Type I hypersensitivity": 3.531602693577246, "Type III immune complex mediated reaction": 47.49188775263992, "Type IV hypersensitivity reaction": 2.6956169732511013, "Unevaluable event": 2.7754179499602847, "Urine ketone body present": 14.100172757264286, "Vision blurred": 2.5713904496464823, "Visual impairment": 4.669958916091689, "Weight increased": 3.0030529936646846, "Wheelchair user": 6.770497333516218, "Wrong product administered": 72.09983406611124, "Wrong technique in device usage process": 7.3483526810313, "Wrong technique in product usage process": 2.171996479576765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1020.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1020.json
index 9b8b3923d27..81d42b5aeff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1020.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1020.json
@@ -1 +1 @@
-{"Amnesia ": 58.49653583304914, "Anxiety ": 2.5182975219052115, "Chemical submission ": 19458.108500057097, "Drug abuse ": 86.9809708477372, "Drug dependence ": 7.616059680106968, "Injection ": 13466.474301417627, "Loss of consciousness ": 4.45683785537527, "Somnolence ": 3.336490258118699, "Substance abuse ": 39.7798324017028, "Vomiting ": 2.046888396228674}
\ No newline at end of file
+{"Activated partial thromboplastin time prolonged": 5.483916253970602, "Acute respiratory failure": 16.77516946998773, "Adenovirus infection": 11.536564054113493, "Ankle fracture": 2.7369788983894483, "Apnoea": 8.790394260314505, "Appendicitis": 2.5298747996263806, "Arachnoiditis": 96.45144110812238, "Aspiration": 33.10227313430038, "Atelectasis": 33.12181758665838, "Autism spectrum disorder": 5.348817702298185, "Back pain": 3.958708126764131, "Bacteraemia": 3.8972613411075407, "Brain death": 11.070390026079266, "Brain injury": 8.162099182819983, "Bronchial secretion retention": 60.50588926688396, "Bronchiolitis": 21.271557242793808, "Bronchitis": 3.5488616282646763, "COVID-19 pneumonia": 3.458310336004075, "CSF pressure increased": 767.8668887336981, "CSF protein increased": 130.96199138448975, "CSF test abnormal": 61.07861641853554, "Cardiac arrest": 4.748934470221276, "Cardio-respiratory arrest": 7.501035723460521, "Cerebrospinal fluid leakage": 174.45748391588495, "Choking": 6.074218162951523, "Chronic respiratory failure": 83.49504945234207, "Clostridium difficile infection": 2.439469699591208, "Death": 2.7638602143759345, "Dehydration": 2.5485994093461226, "Device dislocation": 22.001517168446597, "Device related infection": 4.573279179665016, "Dysphagia": 3.8667067467362215, "Enterovirus infection": 171.5457392307427, "Faecaloma": 6.859016139206288, "Femur fracture": 16.382098824429015, "Foot fracture": 2.061476419417024, "Gait inability": 6.485456111872511, "Gastroenteritis": 3.977676834297863, "Gastroenteritis viral": 8.37322402749472, "Gastrointestinal infection": 18.743216724599115, "Hip fracture": 4.253945306229179, "Hydrocephalus": 37.80372092143507, "Hyperthermia": 2.1185299658147625, "Hypotonia": 2.3211949837258525, "Hypoxia": 2.6077343636746, "Increased appetite": 2.183575142400596, "Increased bronchial secretion": 32.878367472672025, "Infection": 3.2193352830439386, "Intracranial pressure increased": 24.771798699238182, "Joint dislocation": 19.576110150056387, "Kyphosis": 19.4294991677899, "Lower limb fracture": 6.242113081147199, "Malnutrition": 15.777376221445708, "Mechanical ventilation complication": 111.4787948553636, "Meningitis": 10.622511670869004, "Meningitis aseptic": 15.887930131253365, "Meningitis bacterial": 40.26448965100187, "Meningitis chemical": 162.41417442634565, "Metapneumovirus infection": 58.59525912964613, "Mobility decreased": 2.969403561972793, "Motor dysfunction": 19.01756437435784, "Muscle contracture": 22.321433396426976, "Muscle tightness": 3.501321337847505, "Muscular weakness": 2.584331345227675, "Nasopharyngitis": 2.170425197082495, "Nephrolithiasis": 5.844654408180429, "Neurological examination abnormal": 194.5464689476435, "Neurological procedural complication": 1658.1405853221372, "Oxygen saturation decreased": 5.296458531195402, "Parainfluenzae virus infection": 51.23897082039803, "Physical examination abnormal": 263.044119806319, "Pleocytosis": 61.1953986922888, "Pneumonia": 7.763580444698442, "Pneumonia aspiration": 7.300812164484346, "Pneumonia bacterial": 5.863496938056331, "Pneumonia respiratory syncytial viral": 60.99532952499428, "Pneumonia viral": 25.57541487592364, "Pneumothorax": 11.107134247403348, "Polyuria": 2.795973211520785, "Post lumbar puncture syndrome": 6081.1811400013785, "Post procedural complication": 57.565698813811885, "Post procedural fever": 204.8236967187005, "Post procedural haematoma": 19.88214714778649, "Post procedural haemorrhage": 7.181089276620807, "Post procedural infection": 23.51661666310653, "Post procedural swelling": 107.72222377474203, "Prescribed underdose": 7.158483424727773, "Procedural anxiety": 278.9977731143591, "Procedural complication": 72.53106069592043, "Procedural headache": 469.6356570752501, "Procedural nausea": 191.43637376659936, "Procedural pain": 120.87952076780572, "Procedural vomiting": 231.11594451421843, "Protein total increased": 13.204125319543, "Protein urine present": 10.162907183565522, "Proteinuria": 7.17713036823594, "Pseudomonas infection": 8.923477398241392, "Radicular pain": 83.89137901624666, "Renal tubular acidosis": 16.411660718642572, "Respiratory arrest": 8.090625846430132, "Respiratory disorder": 19.68683494139902, "Respiratory distress": 7.306733321550579, "Respiratory failure": 9.519181722401813, "Respiratory syncytial virus infection": 45.103951379338014, "Respiratory tract infection": 31.54222771694424, "Respiratory tract infection viral": 47.9386322924686, "Respiratory tract procedural complication": 1034.927608000197, "Rhinovirus infection": 215.56437940435765, "Road traffic accident": 2.320446465359991, "SARS-CoV-2 test positive": 4.789618612811015, "Salivary hypersecretion": 5.262469862050283, "Sciatica": 2.935158369290608, "Scoliosis": 396.9027946407125, "Secretion discharge": 6.885173133584046, "Sepsis": 3.006695459368724, "Sinus tachycardia": 2.5668289144229326, "Spinal deformity": 69.51131926309743, "Spinal disorder": 9.500529832406912, "Spinal fusion surgery": 18.415399745440105, "Spinal implantation": 859.3049643898396, "Spinal muscular atrophy": 3483.2606846503195, "Spinal pain": 3.7459468304097903, "Sudden death": 4.056151798283298, "Therapeutic product effect decreased": 2.681196153624524, "Therapeutic response shortened": 12.41470003414732, "Tibia fracture": 13.395104867026284, "Tracheostomy": 23.75630104692188, "Tracheostomy malfunction": 263.044119806319, "Traumatic lumbar puncture": 2547.739059467472, "Upper respiratory tract infection": 5.099917008781794, "Viral infection": 13.003892029886169, "Viral upper respiratory tract infection": 18.891870948840715, "Vital capacity decreased": 66.0556316173409, "Weight gain poor": 31.273888111899563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1021.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1021.json
index 11fff37bd1e..2b02f3f9f03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1021.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1021.json
@@ -1 +1 @@
-{"Acute generalised exanthematous pustulosis ": 7.403251602720803, "Acute pulmonary oedema ": 8.897214010958006, "Acute respiratory distress syndrome ": 4.355654829220852, "Allergy test negative ": 186.1501833360041, "Anaesthetic complication ": 65.0873203784674, "Anaesthetic complication neurological ": 893.9317810214162, "Anaphylactic reaction ": 16.49165084679229, "Anaphylactic shock ": 109.9967214958737, "Anaphylactoid reaction ": 19.71177305225272, "Anaphylactoid shock ": 212.05232038263395, "Apnoea ": 3.863862385315131, "Atrioventricular block ": 7.754753396190877, "Blood pressure decreased ": 4.48086459989658, "Bradycardia ": 6.111201408025092, "Bradypnoea ": 12.13644301079264, "Bronchospasm ": 67.14935774584228, "Bronchospasm paradoxical ": 74.50156901244907, "Cardiac arrest ": 12.445443274570842, "Cardio-respiratory arrest ": 11.00704668139615, "Cardiogenic shock ": 7.741719728053575, "Cholestasis ": 6.9087089196938845, "Circulatory collapse ": 15.04516960572782, "Coma ": 2.6877120496775144, "Conjunctivitis ": 4.023517925245391, "Cyanosis ": 3.114022813421758, "Eosinophilia ": 6.226639698414206, "Erythema ": 7.066948133596795, "Exposure during pregnancy ": 3.6708429368905486, "Gastritis ": 3.1270129199642613, "Haemodynamic instability ": 18.45473884285001, "Hemiplegia ": 4.1239994903891946, "Hepatic cytolysis ": 7.54066673128345, "Histamine level increased ": 233.4923689841373, "Horner's syndrome ": 157.79323117684072, "Hypersensitivity ": 2.066344387904365, "Hyperthermia malignant ": 133.87630810898844, "Hypotension ": 15.766277213390202, "Hypotonia ": 3.034198419847066, "Hypoxia ": 4.237604610999548, "Inadequate analgesia ": 40.11323721734267, "Incorrect route of product administration ": 2.829203323601296, "Laryngospasm ": 9.679819183490704, "Macule ": 19.15446590647125, "Maternal exposure during delivery ": 66.73311128693486, "Maternal exposure during pregnancy ": 3.148377370358524, "Miosis ": 9.856369291838975, "Myoclonus ": 5.079150875332176, "Neuromuscular blockade ": 151.23454294364646, "Normal newborn ": 9.741556511994713, "Oxygen saturation decreased ": 4.890392953782203, "Paraparesis ": 15.96645380539012, "Pneumonia aspiration ": 5.033002883227971, "Pneumothorax ": 3.622375758224646, "Postoperative delirium ": 809.6657414852194, "Premature baby ": 2.173504966771082, "Procedural hypotension ": 104.79014404852744, "Radiculopathy ": 5.971469817310013, "Rash ": 2.5161780624334424, "Rash maculo-papular ": 4.735983068484234, "Rash morbilliform ": 4.77817246800226, "Respiratory arrest ": 3.5092173992090943, "Respiratory depression ": 21.54729923188729, "Sedation ": 4.0074381768675975, "Sedation complication ": 10.832595028660094, "Shock ": 22.7803855869522, "Shock haemorrhagic ": 4.612095962920212, "Stress cardiomyopathy ": 34.463940685367675, "Tachycardia ": 6.672075120743633, "Toxic epidermal necrolysis ": 2.765564380201957, "Toxic skin eruption ": 5.716324515093811, "Type I hypersensitivity ": 50.08235675337304, "Urinary incontinence ": 2.5027041985782965, "Urticaria ": 4.307513226225706, "Ventricular extrasystoles ": 4.634709394888435, "Ventricular tachycardia ": 2.9120515816660024, "Withdrawal syndrome ": 2.6950279545415987}
\ No newline at end of file
+{"Acute generalised exanthematous pustulosis": 11.069981200907966, "Acute kidney injury": 8.417079097333714, "Aortic valve incompetence": 11.26172231608694, "Ascites": 2.1123389108606587, "Asthenia": 3.96594204412715, "Atrial fibrillation": 2.969582946995795, "Atrioventricular block first degree": 35.271465129672414, "Blood bicarbonate decreased": 18.98393803184759, "Blood creatinine increased": 4.858174509291004, "Blood potassium decreased": 6.036230065080136, "Blood potassium increased": 16.08439894050272, "Blood urea increased": 7.34362224347695, "Bradycardia": 4.585396047739196, "Bradykinesia": 10.960219120471624, "Bundle branch block left": 23.00134101042033, "Cardiac amyloidosis": 112.57641288607954, "Cardiac failure": 3.63413761650154, "Cardiac failure acute": 7.207733421182305, "Cardiac failure chronic": 15.211152678003312, "Cardioactive drug level increased": 11.757587920623507, "Cardiomegaly": 4.050939879640464, "Coagulopathy": 4.444699785685563, "Cognitive disorder": 3.053589141704128, "Coronary artery disease": 2.1205898927138405, "Dehydration": 4.62973990273559, "Dementia": 5.34235615452441, "Drug interaction": 3.2489091043062786, "Drug reaction with eosinophilia and systemic symptoms": 6.398986065335149, "Dyspnoea at rest": 14.06076764485153, "Dysuria": 3.1565959007118662, "Electrocardiogram QRS complex prolonged": 22.59997050775363, "Electrocardiogram QT prolonged": 2.031898119005041, "Electrocardiogram T wave peaked": 125.89105712044372, "Electrocardiogram abnormal": 6.037101156183706, "Electrolyte imbalance": 4.820860539541292, "Exercise tolerance decreased": 3.2828705842567687, "Fall": 2.820583647911803, "Fluid retention": 2.7106136534104337, "Gastric polyps": 23.02311044271998, "Glomerular filtration rate decreased": 3.4408901559498477, "Gynaecomastia": 15.513178101531572, "Haematuria": 2.500963812934925, "Heart failure with reduced ejection fraction": 91.6063468955274, "Hiatus hernia": 9.260051774443756, "Hyperkalaemia": 53.25643824405956, "Hypokalaemia": 4.435649942474549, "Hyponatraemia": 10.747136368819334, "Hypophagia": 3.998935340894473, "Hypotension": 5.581615426928849, "Hypovolaemia": 15.790695183996773, "Left ventricular dysfunction": 7.437639440475072, "Medication error": 3.733613773771204, "Metabolic acidosis": 8.099474746460112, "Mitral valve incompetence": 6.87789401907722, "Mobility decreased": 2.238993735330338, "Motor dysfunction": 9.757556232852007, "Multiple organ dysfunction syndrome": 2.988094860664582, "Muscular weakness": 2.532788072135145, "Neuroglycopenia": 249.2446564928584, "Obstructive pancreatitis": 53.390195120476776, "Oedema peripheral": 3.8156087003344368, "Oliguria": 5.317271328580789, "Orthostatic hypotension": 11.740996879867712, "Parkinsonism": 9.590956800928131, "Premature delivery": 3.4885240994097573, "Product prescribing error": 2.581164084378152, "Pulmonary congestion": 5.502253863263049, "Pulmonary oedema": 2.291952274525096, "Rales": 6.715525512405667, "Renal impairment": 2.70428678288886, "Sedation": 2.249928136106992, "Sinus bradycardia": 9.197482761365116, "Stevens-Johnson syndrome": 12.222780166169269, "Tachypnoea": 2.354324392724259, "Toxic epidermal necrolysis": 2.256699705217657, "Transplant dysfunction": 57.04879384223173, "Type 2 diabetes mellitus": 2.372373180506174, "Urine output decreased": 5.1962731173255845, "Ventricular extrasystoles": 3.74426204197182, "Ventricular tachycardia": 5.602339938636116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1022.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1022.json
index fc05bab5de0..1d7454597ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1022.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1022.json
@@ -1 +1 @@
-{"Anaphylactic reaction ": 45.18999043806067, "Anaphylactic shock ": 25.2329362032695, "Atrial fibrillation ": 8.112470490368743, "Bradycardia ": 22.04753909079276, "Bronchospasm ": 39.75421879118719, "Cardiac arrest ": 16.758361704744704, "Drug interaction ": 9.928121370377337, "Hypotension ": 6.91606460622092, "Neuromuscular block prolonged ": 783.3574580078387, "Neuromuscular blockade ": 1233.7163544188072, "Off label use ": 2.7866687772480945, "Recurrence of neuromuscular blockade ": 1591.5272849619423, "Respiratory failure ": 24.708500671039577, "Tachycardia ": 4.160834080250067}
\ No newline at end of file
+{"Acne": 2.893460566737926, "Acute febrile neutrophilic dermatosis": 6.632525313926249, "Acute lymphocytic leukaemia recurrent": 15.998468666897082, "Acute pulmonary oedema": 4.701705370095726, "Adverse event": 11.49143040148586, "Anaemia": 2.383820857328499, "Ascites": 2.69201418445554, "Aspiration pleural cavity": 197.07918646215867, "Atrial fibrillation": 2.229157145126877, "Back disorder": 2.271186757345953, "Blast cell crisis": 109.189024914848, "Blast cell proliferation": 220.8747091943709, "Blast crisis in myelogenous leukaemia": 48.85539172091863, "Blood disorder": 5.009976933338447, "Bone marrow disorder": 24.010438561433023, "Bone marrow failure": 4.064937760298294, "Bone marrow transplant": 57.56143589411527, "Bone pain": 2.4036667824711304, "Cardiac disorder": 2.8228808922218303, "Cardiac failure": 4.093204463628765, "Cardiac failure congestive": 4.367598778334342, "Cardiomegaly": 2.341395871867739, "Cellulitis": 2.1109676609757853, "Chronic myeloid leukaemia": 31.66536682013635, "Chronic myeloid leukaemia recurrent": 67.67375155388085, "Chronic myeloid leukaemia transformation": 63.31810231488716, "Chylothorax": 246.3563302740834, "Clostridium difficile infection": 2.301920483489054, "Colitis": 5.14594226288751, "Cytomegalovirus colitis": 7.744914990893187, "Cytomegalovirus enterocolitis": 20.09020762833893, "Cytopenia": 14.179689451583016, "Death": 3.09455298187857, "Dialysis": 2.040094019183029, "Drug resistance": 2.3760629427418105, "Dyspnoea exertional": 2.16250888703444, "Electrocardiogram QT prolonged": 3.0042365483041027, "Enterocolitis": 4.006317435139912, "Enterocolitis haemorrhagic": 17.93716725282123, "Eye haemorrhage": 2.0008541084455365, "Fluid retention": 13.005368334440652, "Full blood count decreased": 12.55605821348726, "Gallbladder disorder": 2.766055353890416, "Gastrointestinal haemorrhage": 3.396288063688648, "Gastrointestinal infection": 3.6992038061813335, "Gene mutation": 30.12755491850753, "Generalised oedema": 3.0215952709851184, "Graft versus host disease": 4.341178167173663, "Haematochezia": 2.255193461066019, "Haematotoxicity": 4.18158776538611, "Haemorrhage": 2.1732486015628365, "Haemothorax": 9.277347037846702, "Hospitalisation": 12.142961245391785, "Intentional product use issue": 4.016194459524272, "Internal haemorrhage": 4.192102329831255, "Intestinal haemorrhage": 2.676908134644101, "Iron deficiency anaemia": 2.6313255460329703, "Leukaemia": 9.608490019694605, "Leukaemia recurrent": 11.617710539545142, "Lower gastrointestinal haemorrhage": 3.1101176952098406, "Lung disorder": 2.0759857588599435, "Lung infiltration": 4.6469046727646095, "Lymphocytosis": 10.320595242868482, "Malignant neoplasm progression": 11.372091628735523, "Nephrotic syndrome": 4.127880030466489, "Neuropathy peripheral": 2.752704715333511, "Oedema": 2.82796459500404, "Pancytopenia": 5.439390932370854, "Pericardial effusion": 37.583723789601954, "Peripheral arterial occlusive disease": 5.745206768347362, "Philadelphia chromosome positive": 192.4662638449781, "Platelet count decreased": 2.826488156533723, "Platelet count increased": 3.0766663670874514, "Platelet transfusion": 16.0038120670919, "Pleural effusion": 109.1673010576023, "Pleurisy": 14.550612891694469, "Pneumonia": 3.620762731437638, "Pneumonia fungal": 4.46817887476219, "Prescribed underdose": 52.93167860462712, "Pulmonary alveolar haemorrhage": 2.1635207220795505, "Pulmonary arterial hypertension": 29.83150528206673, "Pulmonary congestion": 2.073864447408475, "Pulmonary hypertension": 36.72715378548201, "Pulmonary oedema": 35.807546041200844, "Rectal cancer": 5.135921517206346, "Red blood cell count decreased": 3.0576929227133136, "Respiratory tract congestion": 3.682723173175603, "Retinal haemorrhage": 2.575983980954837, "Right ventricular failure": 3.661962088952216, "Splenomegaly": 4.41393720894199, "Stem cell transplant": 26.56070785679696, "Subdural haematoma": 3.094663916061771, "Therapeutic response decreased": 4.487283938373748, "Therapy non-responder": 4.270333716845658, "Thrombocytopenia": 3.489514739676048, "Transfusion": 8.58733568032972, "Transplant": 8.925170501458705, "Tumour lysis syndrome": 3.264092860971662, "White blood cell count abnormal": 3.2207737585495084, "White blood cell count increased": 3.6235320047540127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1023.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1023.json
index 17dc5e56574..c84975fd882 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1023.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1023.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 16.54972415045368, "Clostridium difficile colitis ": 13.851988879341262, "Decreased appetite ": 2.062683688096459, "Diarrhoea ": 2.794456665558751, "Disease progression ": 13.34261564834975, "Drug interaction ": 6.668701108923167, "Electrocardiogram QT prolonged ": 16.8902170475667, "Epistaxis ": 2.618178916718264, "Hair colour changes ": 30.246649169899676, "Hypertension ": 8.780290190764378, "Hypothyroidism ": 18.01285600587825, "Leukopenia ": 4.028926241635756, "Malignant neoplasm progression ": 4.075736551178736, "Mucosal inflammation ": 17.0382805141317, "Neoplasm progression ": 6.036755141801905, "Nephrotic syndrome ": 23.75094271928633, "Neutropenia ": 4.956532731235687, "Osteonecrosis of jaw ": 86.25154931662397, "Pain in jaw ": 8.918078838186114, "Palmar-plantar erythrodysaesthesia syndrome ": 21.856100254812542, "Periodontal disease ": 259.7499988829635, "Posterior reversible encephalopathy syndrome ": 22.447372708534235, "Proteinuria ": 9.455354143398926, "Stomatitis ": 4.320431895169893, "Thrombocytopenia ": 5.872105572323824, "Thrombotic microangiopathy ": 30.93138083052052}
\ No newline at end of file
+{"Completed suicide": 53.30328829485575, "Drug interaction": 16.656255131491992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1024.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1024.json
index f5c132db0f1..92486b292c1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1024.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1024.json
@@ -1 +1 @@
-{"Agitation ": 3.851180370650725, "Depression ": 4.237372718495712, "Drug interaction ": 3.341036344521052, "Foetal exposure during pregnancy ": 3.8997189349624337, "Gamma-glutamyltransferase increased ": 14.588066774648752, "General physical health deterioration ": 3.373776232891266, "Hallucination ": 4.280479504365571, "Hepatic steatosis ": 13.683564925922584, "Hepatitis ": 8.30024654642637, "Lactic acidosis ": 10.085088378464995, "Nightmare ": 8.542291872123538, "Pancreatitis ": 3.2123651582107637, "Pancreatitis acute ": 12.270590573638067, "Rash maculo-papular ": 7.275481477147968, "Suicidal ideation ": 5.695086941939819}
\ No newline at end of file
+{"Abnormal behaviour": 3.405736030382148, "Abnormal dreams": 2.702998184368318, "Aggression": 4.866415552809968, "Agitation": 3.947008318390966, "Akinesia": 60.21426549310371, "Apathy": 2.131198435493688, "Aspiration": 4.96983879617291, "Behaviour disorder": 3.3670274828395783, "Choking": 5.741959648652567, "Chromaturia": 20.417729351749163, "Colitis microscopic": 29.750259077171357, "Confusional state": 4.2149965511639325, "Coordination abnormal": 2.886576406507133, "Dehydration": 2.2680766342227727, "Delirium": 4.6624987622591725, "Delusion": 7.979028547149376, "Dementia": 6.316883951515079, "Disease progression": 3.296813932488486, "Disorientation": 3.98730445254888, "Dopamine dysregulation syndrome": 223.59585536084668, "Dyskinesia": 30.289171692590585, "Dysphagia": 20.125659654680128, "Dysstasia": 5.67475735952977, "Dystonia": 10.376329680771184, "Eating disorder": 3.147996652888444, "Fall": 4.120353612394122, "Feeding disorder": 2.8815379729520307, "Femur fracture": 3.138210888517888, "Fracture": 5.769176202321302, "Freezing phenomenon": 69.77136538612962, "Gait disturbance": 3.877088983650253, "Gait inability": 3.887561247038376, "Gambling disorder": 38.28915995569985, "General physical health deterioration": 3.102061139066422, "Hallucination": 14.215252239620208, "Hallucination, auditory": 3.80876539209585, "Hallucination, visual": 20.04913758685486, "Hip fracture": 3.4761500931010025, "Hyperkinesia": 34.63431122896784, "Hypersexuality": 88.54307920972444, "Hypokinesia": 10.896466820444084, "Ileus": 6.712852956988915, "Impulse-control disorder": 33.91390444203331, "Incorrect dose administered": 2.822161459869556, "Libido increased": 20.785353313834342, "Motor dysfunction": 5.006339917569944, "Movement disorder": 5.751234979080472, "Muscle rigidity": 16.086162379776695, "Musculoskeletal stiffness": 3.3576030236252605, "Nervousness": 3.309137962557001, "Neuroleptic malignant syndrome": 3.49465684394376, "Nightmare": 2.5097010206155463, "On and off phenomenon": 227.7982496854132, "Oral mucosal discolouration": 96.12341708593657, "Orthostatic hypotension": 6.362135201932418, "Paralysis": 4.33061368972657, "Paranoia": 5.749322435225319, "Parkinson's disease": 196.40166614224387, "Parkinsonian crisis": 840.9120212576136, "Parkinsonism": 7.755478468608146, "Pneumonia aspiration": 8.312145081727648, "Product complaint": 20.89472713737045, "Product prescribing error": 4.978415313901908, "Product quality issue": 2.3635455221260697, "Product residue present": 10.629254931708047, "Product size issue": 27.248367343819105, "Product supply issue": 35.574906451178286, "Product use complaint": 12.432151262976552, "Psychomotor hyperactivity": 11.438706786685517, "Psychotic disorder": 4.340717643291604, "Rhabdomyolysis": 2.870390291627024, "Salivary hypersecretion": 5.169761978430663, "Serotonin syndrome": 2.6394945306584607, "Somnolence": 2.16104717746886, "Speech disorder": 4.318665600082211, "Stereotypy": 36.10581657759274, "Sudden onset of sleep": 37.57989661377093, "Therapeutic product effect decreased": 2.360618906236981, "Therapeutic response shortened": 38.01429181564257, "Therapy cessation": 11.894260365424236, "Tremor": 4.080156149610642, "Urinary tract infection": 2.007486362317123, "Weight decreased": 2.2238754835402563, "Wrong technique in product usage process": 16.15472535526383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1025.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1025.json
index 42c53ac85e8..1b9adbd6a85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1025.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1025.json
@@ -1 +1 @@
-{"Abdominal abscess ": 2.33927761709552, "Abdominal infection ": 3.7622424389805738, "Acute cholecystitis necrotic ": 7.110934820664927, "Ageusia ": 7.004511393798643, "Alveolar soft part sarcoma ": 15.9222770164308, "Anaemia ": 2.3983769610776533, "Anal abscess ": 4.059823448383918, "Anal fissure ": 4.543848224075102, "Anal fistula ": 4.899021518653251, "Anal haemorrhage ": 8.00869605571562, "Anal inflammation ": 10.1634339600209, "Anal injury ": 36.23832607887527, "Anal ulcer ": 8.107736793229172, "Angular cheilitis ": 4.024162274141954, "Anorectal discomfort ": 4.3090965652021485, "Anorectal disorder ": 5.018349112826401, "Aortic dissection ": 3.995738296764016, "Aphthous ulcer ": 5.682940200067657, "Appetite disorder ": 2.6855515473252405, "Ascites ": 4.018100715684891, "Asthenia ": 2.172801656180704, "Blister ": 3.3221446835384087, "Blister infected ": 6.372988206573382, "Blood albumin decreased ": 2.6280549115164717, "Blood bilirubin abnormal ": 3.538830123282134, "Blood blister ": 3.5004321521275648, "Blood calcium abnormal ": 2.5777052270661347, "Blood calcium increased ": 2.3029227123000924, "Blood creatine increased ": 2.75239839647671, "Blood creatinine abnormal ": 3.4524950848508937, "Blood creatinine increased ": 2.315404100599315, "Blood disorder ": 3.284611634510012, "Blood magnesium decreased ": 3.281181068070249, "Blood pressure abnormal ": 2.330076202578719, "Blood pressure fluctuation ": 2.0213474368525723, "Blood pressure increased ": 3.850220793460661, "Blood sodium decreased ": 3.658669198138153, "Blood sodium increased ": 2.228579761191265, "Blood test abnormal ": 2.342002291788698, "Blood thyroid stimulating hormone abnormal ": 5.23065625266773, "Blood thyroid stimulating hormone decreased ": 2.0195331748934207, "Blood thyroid stimulating hormone increased ": 14.966120304829834, "Blood triglycerides abnormal ": 3.5956512679216903, "Blood urea increased ": 2.212229675120896, "Blood uric acid increased ": 2.141116813551358, "Blood urine ": 7.691889612945651, "Blood urine present ": 4.38386728486451, "Bone lesion ": 2.530411534599225, "Burn oesophageal ": 2.1678413293455363, "Burn oral cavity ": 6.895541164197233, "Cachexia ": 2.438355218905389, "Cancer pain ": 8.961721650194969, "Carcinoid tumour ": 3.384368532312146, "Cardiac failure ": 2.4896471732445598, "Cardiopulmonary failure ": 24.86169045308845, "Cardiotoxicity ": 2.1792122194219776, "Central hypothyroidism ": 2.7399719840646366, "Chapped lips ": 5.867829370594369, "Cholecystitis ": 3.4512727976846582, "Cholecystitis infective ": 5.337919942627307, "Chromaturia ": 3.326256621772179, "Clear cell renal cell carcinoma ": 9.14123095287988, "Colonic fistula ": 7.961687045441544, "Coma hepatic ": 2.4197168042214634, "Constipation ": 2.528345549625667, "Death ": 5.636203431318115, "Decreased appetite ": 4.008740862829962, "Decreased immune responsiveness ": 7.925060994124159, "Decubitus ulcer ": 6.584985154215838, "Dehydration ": 3.1335681866950984, "Diarrhoea ": 2.668875619308291, "Disease progression ": 32.37213242999277, "Disseminated intravascular coagulation ": 2.1244101766053984, "Diverticular perforation ": 2.4188467729249146, "Dry mouth ": 2.3029525638756594, "Dry skin ": 9.181740863655849, "Duodenal perforation ": 2.306487337593943, "Dyschezia ": 3.758211698030864, "Dysentery ": 5.161426751683807, "Dysgeusia ": 3.3466316481267917, "Dyspepsia ": 3.971632303765347, "Eating disorder ": 8.329306325406447, "Ejection fraction decreased ": 4.432018867359169, "Epistaxis ": 3.755490667230447, "Eructation ": 2.502786830929825, "Exposed bone in jaw ": 18.616578988131163, "Eye colour change ": 5.289412305891497, "Eye swelling ": 2.502442721798147, "Eyelash discolouration ": 44.67562738771224, "Eyelid oedema ": 2.043527707878632, "Eyelid pain ": 2.306487337593943, "Faeces discoloured ": 2.147151199321915, "Faeces soft ": 2.475496174019185, "Feeding disorder ": 6.7665132466120825, "Fistula ": 3.5031858035228205, "Fistula of small intestine ": 9.323755396881577, "Flatulence ": 4.166439158126159, "Fluid intake reduced ": 5.140574056325409, "Food intolerance ": 2.046473677958786, "Full blood count decreased ": 2.001672263402399, "Fungal skin infection ": 2.108026994381724, "Furuncle ": 4.656549656530522, "Gait inability ": 2.52343875919667, "Gallbladder disorder ": 2.166864749064883, "Gastric haemorrhage ": 5.343155196045708, "Gastric ulcer ": 2.0826286581179727, "Gastric ulcer perforation ": 2.268310548055036, "Gastritis ": 2.101002121416945, "Gastrointestinal injury ": 3.357586225954541, "Gastrointestinal oedema ": 3.1279131691249797, "Gastrointestinal perforation ": 5.372064203411801, "Gastrointestinal stromal tumour ": 210.41239906726847, "Gastrooesophageal reflux disease ": 2.479481987540652, "Generalised oedema ": 2.37416173373596, "Genital discomfort ": 5.659817539071863, "Genital erythema ": 5.40134910345629, "Genital rash ": 7.368849036097253, "Gingival bleeding ": 4.027269228774142, "Gingival discomfort ": 6.065695107302715, "Gingival disorder ": 6.232539746934809, "Gingival pain ": 10.84917892171323, "Gingival recession ": 3.6087781491987703, "Gingival swelling ": 6.428414828458981, "Gingivitis ": 2.193372893294227, "Glossitis ": 5.440170499191932, "Glossodynia ": 3.873448485935104, "Gout ": 2.2147545035919376, "Haematemesis ": 3.158565124587331, "Haematochezia ": 2.6888837016044844, "Haematotoxicity ": 2.266911024615205, "Haematuria ": 2.0475593433120958, "Haemoglobin decreased ": 2.490384422196764, "Haemoptysis ": 3.3301557083350573, "Haemorrhage ": 2.884135612966572, "Haemorrhage urinary tract ": 4.063117811264993, "Haemorrhagic diathesis ": 2.2546171686700407, "Haemorrhoidal haemorrhage ": 6.045567618161792, "Haemorrhoids ": 3.584780584242671, "Hair colour changes ": 40.61551697744172, "Hair disorder ": 2.4481902326794844, "Hair texture abnormal ": 2.6623286320253694, "Hand-foot-and-mouth disease ": 5.539166213954836, "Hepatic infection ": 3.936252130158774, "Hepatorenal failure ": 2.5091969475583973, "Hernia ": 2.340069430387256, "Hiccups ": 5.597661066415836, "Hydrothorax ": 7.526787478674223, "Hyperaesthesia ": 2.661547640044298, "Hyperaesthesia teeth ": 2.502510690870667, "Hyperchlorhydria ": 16.614087871867753, "Hypercreatininaemia ": 2.9382717978859705, "Hyperkeratosis ": 19.395564874249903, "Hypertension ": 4.111030098479426, "Hyperthyroidism ": 2.772412570594056, "Hypoalbuminaemia ": 2.456992256620264, "Hypogeusia ": 11.051951425204097, "Hypophagia ": 4.352521262473482, "Hypothyroidism ": 8.881466818030372, "Impaired healing ": 2.786844517765515, "Incision site pain ": 5.733813722048219, "Ingrowing nail ": 3.779585730062008, "Inguinal hernia ": 2.2976566249673835, "Internal haemorrhage ": 2.5777776666964924, "Intestinal fistula ": 5.006097738890476, "Intestinal haemorrhage ": 2.5873097608556184, "Intestinal obstruction ": 2.1193668126298646, "Intestinal perforation ": 4.532469958492267, "Jaundice ": 2.2536639121021818, "Jaw disorder ": 4.672250491338108, "Lacrimal disorder ": 6.918533337798009, "Lacrimation increased ": 2.35558299120903, "Large intestine perforation ": 2.8047724397978486, "Leukoencephalopathy ": 2.124562452622696, "Leukopenia ": 2.419763332385862, "Limb injury ": 3.076252804424091, "Lip blister ": 4.015342487820515, "Lip disorder ": 2.245602234128931, "Lip dry ": 3.3956769905256694, "Lip exfoliation ": 3.4663938587292744, "Lip injury ": 2.1785697272631683, "Lip pain ": 2.814470490632392, "Loose tooth ": 6.674271686234114, "Malignant pleural effusion ": 2.0739808227013725, "Mallory-Weiss syndrome ": 2.76989674079206, "Mastication disorder ": 5.709438240412879, "Mean cell haemoglobin concentration decreased ": 2.1676870297869315, "Mean cell volume increased ": 2.258146127077712, "Metastatic renal cell carcinoma ": 207.67602263722588, "Mouth haemorrhage ": 4.48645789071857, "Mouth injury ": 43.57623112608271, "Mouth ulceration ": 7.905219352681657, "Mucosal disorder ": 2.731271672595573, "Mucosal inflammation ": 10.791726273551149, "Multiple organ dysfunction syndrome ": 2.706371180706926, "Myxoedema ": 8.682577424173445, "Nail bed bleeding ": 4.857093848368591, "Nail discolouration ": 5.7942836014471215, "Nail disorder ": 2.415419447979621, "Nasal discomfort ": 2.9590174337254664, "Nasal disorder ": 4.633536241178054, "Nasal dryness ": 4.625529522228055, "Nasal injury ": 5.564279729652812, "Nasal septum perforation ": 3.333255921609096, "Neoplasm malignant ": 2.373006754990978, "Neoplasm progression ": 34.32529094049958, "Neoplasm recurrence ": 4.997523244286912, "Nephrectomy ": 2.84234231184438, "Nephrotic syndrome ": 8.499525200018242, "Nodule ": 2.042683594566028, "Noninfective gingivitis ": 4.421411936043727, "Nutritional condition abnormal ": 3.58081522979573, "Ocular vascular disorder ": 2.769495280217558, "Oesophageal haemorrhage ": 3.692904151301261, "Oesophageal ulcer ": 4.2642676942846585, "Oesophagitis ": 2.1064233860845234, "Oesophagitis ulcerative ": 3.763293724415581, "Onychalgia ": 5.006097738890476, "Onychoclasis ": 2.2768250086522146, "Onycholysis ": 2.3182319402534266, "Oral discomfort ": 6.408973951329068, "Oral disorder ": 5.317212899986992, "Oral infection ": 2.229559121109506, "Oral mucosal blistering ": 8.637353692483547, "Oral mucosal erythema ": 4.039736141105351, "Oral mucosal exfoliation ": 4.491476899651225, "Oral pain ": 19.97053325621103, "Orbital oedema ": 4.659195817524316, "Organ failure ": 8.207455905864984, "Oropharyngeal plaque ": 3.277288597469136, "Osteonecrosis of jaw ": 12.097106933796264, "Palmar erythema ": 4.192009470704741, "Palmar-plantar erythrodysaesthesia syndrome ": 24.47753708966814, "Pancreatic neuroendocrine tumour ": 20.865581339530547, "Pancreatic neuroendocrine tumour metastatic ": 12.176925220462872, "Pathological fracture ": 2.895902767683288, "Penile exfoliation ": 12.010963633660152, "Penile haemorrhage ": 3.411882391631947, "Pericardial effusion ": 2.127330191892572, "Perineal pain ": 4.011127567991756, "Periorbital oedema ": 4.995571697315627, "Peritonitis ": 2.16712664023413, "Phaeochromocytoma ": 2.6045755469495013, "Pharyngeal inflammation ": 2.286738651842473, "Pharyngeal ulceration ": 3.232718349059031, "Pigmentation disorder ": 2.337134739937951, "Plantar erythema ": 14.82722095857907, "Platelet count decreased ": 7.032405069777323, "Platelet disorder ": 2.532136574134029, "Pleural effusion ": 3.764100273041752, "Pneumatosis intestinalis ": 2.0832170272996344, "Posterior reversible encephalopathy syndrome ": 2.1505904583878857, "Primary hypothyroidism ": 5.188114909023682, "Proctalgia ": 6.404359917165865, "Prostatomegaly ": 2.153371764956921, "Protein total decreased ": 3.1245991730951266, "Protein urine present ": 3.368216321373712, "Proteinuria ": 2.8028325769048084, "Pulmonary oedema ": 2.3141985602382054, "Purulence ": 2.782302584296983, "Pyoderma gangrenosum ": 5.948989701493863, "Rectal abscess ": 2.927260241353654, "Rectal ulcer ": 3.1452322596386515, "Red blood cell abnormality ": 2.321133591053897, "Red blood cell count decreased ": 3.086846578551244, "Reflux gastritis ": 7.967870008859985, "Renal cancer ": 8.196619117836741, "Renal cancer metastatic ": 99.11700097665268, "Renal cancer stage IV ": 61.7367832319189, "Renal cell carcinoma ": 136.53176194939937, "Renal cell carcinoma stage IV ": 33.89965694990128, "Renal disorder ": 2.265627252494817, "Renal haemorrhage ": 4.499243594438481, "Renal impairment ": 2.3718856591834614, "Renal vein thrombosis ": 3.4076818106792226, "Retching ": 2.907338384071568, "Scrotal erythema ": 9.50916987747825, "Second primary malignancy ": 18.21572432809746, "Single functional kidney ": 4.721703389372228, "Skin abrasion ": 2.739269224730219, "Skin atrophy ": 6.306909146285564, "Skin depigmentation ": 4.1650298740959295, "Skin discolouration ": 5.656792768959901, "Skin disorder ": 2.813063745046134, "Skin exfoliation ": 6.4994912659254, "Skin fissures ": 15.582741294057357, "Skin haemorrhage ": 3.2628695218153405, "Skin hypertrophy ": 3.940438312547662, "Skin injury ": 2.564304644407424, "Skin irritation ": 2.930000802186153, "Skin lesion ": 3.363606272604888, "Skin papilloma ": 3.456326112235839, "Skin sensitisation ": 9.767066845952687, "Skin toxicity ": 5.456806706048685, "Skin ulcer ": 3.538808031231361, "Skin wound ": 3.636546752956346, "Sluggishness ": 2.2431251981517475, "Small intestinal perforation ": 2.0281414308822, "Spinal disorder ": 2.265858888139252, "Stomatitis ": 10.170597585774994, "Sweat discolouration ": 8.891895817495675, "Taste disorder ": 13.197897258188377, "Temperature intolerance ": 2.4802620551109054, "Testicular disorder ": 2.0327858945438604, "Testicular swelling ": 2.178794798929398, "Throat lesion ": 12.909425879042338, "Thrombocytopenia ": 3.39318870202276, "Thrombotic microangiopathy ": 2.2883090351839863, "Thrombotic thrombocytopenic purpura ": 2.1413072259441828, "Thyroid disorder ": 9.351179517078643, "Thyroid function test abnormal ": 10.94891047790884, "Thyroid hormones increased ": 3.547704337880089, "Thyroxine decreased ": 5.489121593932908, "Tongue blistering ": 6.136611864544869, "Tongue discomfort ": 7.15119471608903, "Tongue disorder ": 6.277994334515668, "Tongue dry ": 4.058043896172285, "Tongue erythema ": 6.330584823094933, "Tongue exfoliation ": 6.761427127662978, "Tongue injury ": 11.86010907197928, "Tongue rough ": 5.149123071304462, "Tongue ulceration ": 2.4040576053361056, "Tooth abscess ": 2.943595622265882, "Tooth disorder ": 4.390430415430378, "Tooth infection ": 3.2701134605073365, "Toothache ": 2.256764396915057, "Trichorrhexis ": 2.1886140055282137, "Tumour haemorrhage ": 17.858841824044323, "Tumour lysis syndrome ": 3.595884119268597, "Tumour necrosis ": 4.978590369086888, "Tumour pain ": 23.993816105382432, "Tumour rupture ": 26.251617964191645, "Urethral obstruction ": 8.151174145499338, "Urinary bladder haemorrhage ": 2.4395608394843777, "Urinary tract disorder ": 2.013013165515432, "Vena cava thrombosis ": 6.374475723901832, "Walking disability ": 2.1783393726089675, "Weight decreased ": 3.190539687194948, "Weight fluctuation ": 5.697457395267292, "White blood cell count decreased ": 2.9915391305018275, "Wound ": 2.439009887370276, "Wound complication ": 4.933854576239964, "Wound dehiscence ": 4.327304024824957, "Wound haemorrhage ": 2.5952005525565465, "Wound infection ": 2.8504652179302346, "Yellow skin ": 81.64724897614563}
\ No newline at end of file
+{"Abdominal pain": 3.699398444925811, "Lactic acidosis": 59.73239803503783, "Lipoatrophy": 502.6771923047401, "Pancreatitis": 11.936607486507832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1026.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1026.json
index c1671e50250..951cd01fb9c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1026.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1026.json
@@ -1 +1 @@
-{"Adverse event ": 6.207632202515212, "Agitation ": 3.840086729726572, "Akathisia ": 54.24927311229766, "Blood creatine phosphokinase increased ": 4.372535158103086, "Bradykinesia ": 44.57062450084656, "Delirium ": 2.5435506695251493, "Disease recurrence ": 4.334377342903216, "Disorientation ": 6.522114262989159, "Drug-induced liver injury ": 3.634151464170952, "Dysarthria ": 11.53932727711263, "Dysgeusia ": 10.523392391982188, "Dyskinesia ": 9.832642160628982, "Dysphagia ": 3.72985930246459, "Dystonia ": 11.28204736198916, "Electrocardiogram QT prolonged ": 2.6684345088925614, "Extrapyramidal disorder ": 65.71557977440469, "Generalised tonic-clonic seizure ": 6.330328912397482, "Hospitalisation ": 3.449759212018085, "Hypoaesthesia oral ": 22.59341818626025, "Incorrect route of product administration ": 23.306713323462887, "Increased appetite ": 13.876496757354449, "Insomnia ": 2.409123188764614, "Mania ": 13.290526507603497, "Muscle rigidity ": 13.567981271452318, "Muscle twitching ": 3.480614704247663, "Nervousness ": 2.9747076280888964, "Neuroleptic malignant syndrome ": 59.92183755876987, "Off label use ": 4.2922653260698045, "Oral dysaesthesia ": 163.14584172802412, "Paraesthesia oral ": 5.346089278198875, "Parkinsonism ": 42.65624719921861, "Pneumonia aspiration ": 12.841027614980089, "Polydipsia ": 25.35471915052848, "Prescribed overdose ": 9.10113487826083, "Product taste abnormal ": 23.7928495376452, "Psychomotor hyperactivity ": 13.140979296140326, "Restless legs syndrome ": 12.21988547548867, "Restlessness ": 6.105980804142208, "Rhabdomyolysis ": 7.34031382418971, "Salivary hypersecretion ": 9.417935945721217, "Schizophrenia ": 50.00330337169883, "Sedation ": 38.9396529498552, "Sedation complication ": 44.55508030635309, "Somnolence ": 3.4205957278044186, "Sopor ": 12.741456486049302, "Suicidal ideation ": 3.0313231557855578, "Suicide attempt ": 5.416595422515599, "Tongue oedema ": 10.430493009811324, "Tooth discolouration ": 24.008684659261984, "Treatment noncompliance ": 3.565968694159596, "Underdose ": 4.4439306238259295, "Urinary incontinence ": 9.408509834622276, "Urinary retention ": 5.11871772005341, "Water intoxication ": 158.27905800056652, "Weight increased ": 2.8009153058188665}
\ No newline at end of file
+{"Abdominal abscess": 5.681127129346161, "Abdominal operation": 9.66384820586531, "Abortion infected": 71.92641011943233, "Abortion spontaneous": 3.787954466669033, "Abscess": 4.911605103130762, "Abscess intestinal": 9.54941805447604, "Acarodermatitis": 5.648569464979159, "Accident at work": 4.154637204086062, "Accidental exposure to product": 5.365478909753827, "Actinic keratosis": 2.1064531941947773, "Adenocarcinoma": 3.6225793491616263, "Adenocarcinoma of colon": 11.529833610117878, "Alopecia areata": 3.8707866072502255, "Anal abscess": 14.177264879162497, "Anal cancer": 10.492368550522537, "Anal fistula": 25.78121449698306, "Anastomotic stenosis": 28.99477233426612, "Ankylosing spondylitis": 2.6271204981734977, "Anogenital warts": 5.7193662850465445, "Anorectal disorder": 2.9031116888972464, "Antinuclear antibody positive": 2.330010660957288, "Antiphospholipid antibodies positive": 8.197757393027254, "Aortic dissection": 2.7141646347987707, "Appendicectomy": 3.391736716243882, "Arthritis": 3.033935403295335, "Arthropod bite": 2.377503199083008, "Atypical mycobacterial infection": 2.708828439774494, "B-cell lymphoma": 4.073738191177917, "Basal cell carcinoma": 6.798883711706655, "Bladder neoplasm": 4.785806571797277, "Bladder transitional cell carcinoma": 9.04259883912143, "Breast cancer": 3.56999425568326, "Breast mass": 2.343467602962819, "Breast neoplasm": 7.163221989481068, "Caesarean section": 2.009027957993999, "Cardiac operation": 2.144960065863128, "Cellulitis": 3.827688036398963, "Cervical dysplasia": 6.370602367375184, "Chemotherapy": 3.017699492965854, "Chikungunya virus infection": 40.77353420047819, "Cholangitis sclerosing": 6.057003084439498, "Cholecystectomy": 4.730481599068673, "Chronic disease": 21.392542805373704, "Clear cell renal cell carcinoma": 3.918734759548834, "Clostridial infection": 4.656332933267311, "Clostridium difficile infection": 5.046323547565862, "Coccidioidomycosis": 7.618320442302831, "Coccydynia": 4.934060822368107, "Colectomy": 14.28843861389704, "Colitis ulcerative": 16.233250958425717, "Colon cancer": 4.531660647555649, "Colorectal adenoma": 3.549986254353587, "Colostomy": 4.43726404744408, "Contraindication to vaccination": 19.238357301427552, "Crohn's disease": 107.30726332570543, "Cutaneous T-cell lymphoma": 13.054535187216883, "Cutaneous lupus erythematosus": 5.862898291641224, "Cutaneous vasculitis": 3.269576169792827, "Cytomegalovirus colitis": 2.433616137760705, "Dactylitis": 12.541443658184368, "Decreased immune responsiveness": 2.5300009352228536, "Defaecation urgency": 4.978926675611783, "Dengue fever": 5.802842051387911, "Dermatitis exfoliative": 3.614521409408253, "Dermatitis exfoliative generalised": 3.7210284104255726, "Dermatitis psoriasiform": 2.211241540140405, "Device defective": 4.521861170488066, "Device deployment issue": 33.05235706914827, "Device issue": 3.995291904146191, "Device leakage": 3.061982861983466, "Diarrhoea haemorrhagic": 2.287763448273924, "Dilated 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positive": 3.323267938928645, "Hysterectomy": 4.660486218927783, "Idiopathic intracranial hypertension": 2.184290362972145, "IgA nephropathy": 8.177090731937334, "Ileal stenosis": 31.13576830552161, "Ileostomy": 16.978702454592298, "Immunosuppression": 2.34499971485353, "Impetigo": 3.4791044953535666, "Inappropriate schedule of product administration": 5.73741846263888, "Incorrect route of product administration": 2.053890608137908, "Infective spondylitis": 14.211824531418817, "Infertility": 3.1802325151009683, "Inflammatory bowel disease": 11.140692687452509, "Infusion related reaction": 5.617281987113422, "Injection related reaction": 2.3989453311664657, "Injection site mass": 2.021899809295095, "Intervertebral discitis": 4.0720775130630775, "Intestinal obstruction": 6.50935217905369, "Intestinal operation": 27.37529494542912, "Intestinal perforation": 2.7100246510323367, "Intestinal resection": 29.873247238992825, "Intestinal stenosis": 74.89779392570269, "Intestinal ulcer": 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"Periodontitis": 6.378619225092533, "Pertussis": 9.813323581256924, "Pharyngitis streptococcal": 2.115780125229289, "Pneumonia legionella": 5.582575628677176, "Pneumonia pneumococcal": 3.01758045622634, "Poor quality product administered": 3.7610729580942976, "Posterior reversible encephalopathy syndrome": 3.166322437772485, "Postoperative wound infection": 3.3379872842766893, "Pouchitis": 23.346697633826054, "Precancerous skin lesion": 7.183135100204376, "Pregnancy of partner": 21.81298035436241, "Premature labour": 2.495150601327828, "Proctocolectomy": 52.2085891163475, "Product dose omission issue": 7.783288354651353, "Product label issue": 6.494708204146062, "Product leakage": 2.7086938895398203, "Product measured potency issue": 5.750538668778316, "Product packaging issue": 5.535449610677518, "Product packaging quantity issue": 3.2769697664943207, "Product storage error": 6.69366271322568, "Product use in unapproved indication": 2.026613474653046, "Product use issue": 8.008907489079398, "Prostate cancer": 5.608163351947523, "Psoriasis": 37.58019488748864, "Psoriasis area severity index increased": 79.88599567142282, "Psoriatic arthropathy": 24.26267140056757, "Pustular psoriasis": 34.08286598345405, "Pustule": 2.0523916506131923, "Pyoderma gangrenosum": 13.10155046679694, "Rash pustular": 2.5973101387200765, "Rectal abscess": 29.601740175848995, "Rectal adenocarcinoma": 10.040194709607931, "Rectal cancer": 8.522347655480072, "Renal mass": 4.032780761220399, "Renal neoplasm": 4.589965377935189, "Respiratory tract infection": 2.9986910778153164, "Retained products of conception": 6.983670274392944, "Rubber sensitivity": 8.560914880083164, "Sacroiliitis": 7.645815520593347, "Sarcoidosis": 3.309966311517723, "Scar pain": 7.141751001225828, "Short-bowel syndrome": 18.467384026809075, "Shoulder operation": 3.574120966631085, "Skin cancer": 4.6242287730388005, "Skin infection": 2.9391541659415528, "Skin papilloma": 3.2685370513751564, "Skin plaque": 2.143091330658451, "Small cell lung cancer": 2.890424121213205, "Small intestinal obstruction": 6.0513285303738105, "Small intestinal perforation": 3.65892771296618, "Small intestinal resection": 16.305133037625076, "Small intestinal stenosis": 34.48916578157253, "Small intestine carcinoma": 4.789336786232356, "Spinal fusion surgery": 2.7135226499579512, "Spinal operation": 2.7199510598072223, "Splenectomy": 3.9807590304861016, "Spondylitis": 3.0788223528479715, "Squamous cell carcinoma": 10.830146839571531, "Squamous cell carcinoma of lung": 9.544844113240032, "Squamous cell carcinoma of skin": 4.26876753882084, "Staphylococcal infection": 3.827844792066186, "Stenosis": 7.634202743584342, "Streptococcal infection": 4.857799790224413, "Subcutaneous abscess": 4.258358248157225, "Subileus": 5.063806943517454, "Surgery": 6.675467132002495, "Sweating fever": 4.5164585556697645, "Syringe issue": 58.23415600419675, "Systemic lupus erythematosus rash": 2.9700677009129333, "T-cell lymphoma": 9.616228481105145, "Testis cancer": 3.332737979450381, "Therapeutic product effect decreased": 4.232244166568535, "Therapeutic product ineffective": 4.155370818920168, "Therapeutic response decreased": 12.212703122672725, "Therapeutic response shortened": 4.264014493443645, "Therapy non-responder": 4.146404401976492, "Thyroid cancer": 4.321058994357875, "Tinea versicolour": 13.000880845114123, "Tongue neoplasm malignant stage unspecified": 6.613194707837242, "Tonsillitis": 3.2264091977766576, "Tooth abscess": 8.439770888180863, "Tooth extraction": 2.2256186450706803, "Tooth infection": 4.496025230104022, "Transitional cell carcinoma": 17.505632330890204, "Tuberculin test positive": 48.61293477738767, "Tuberculosis": 8.72908644899514, "Umbilical hernia": 2.108777209225509, "Underdose": 2.1444840624497385, "Upper respiratory tract infection": 3.1095473195609946, "Uterine cancer": 2.674807731411409, "Vena cava thrombosis": 2.783783765682061, "Viral infection": 2.695894335843977, "Vitiligo": 7.570687223201722, "Vulvovaginal mycotic infection": 2.0665734640888545, "Wrong dose": 2.866702156679754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1027.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1027.json
index 57d11278cac..6d5bd6a5984 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1027.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1027.json
@@ -1 +1 @@
-{"Disease progression ": 17.14924489097697, "Infusion related reaction ": 10.35582239423618, "Neutropenia ": 3.979092548281306, "Off label use ": 6.3660227809156655, "Pneumonia ": 2.8100841058076487, "Thrombocytopenia ": 4.5412374530405}
\ No newline at end of file
+{"Acute kidney injury": 2.2231581024559484, "Haemorrhoids": 13.823249904224234, "Oedema": 5.473815044901856, "Sprue-like enteropathy": 16.07254395745642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1028.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1028.json
index f55a0f653f5..80063b02532 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1028.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1028.json
@@ -1 +1 @@
-{"Blood HIV RNA increased ": 181.838687104936, "Blood cholesterol increased ": 5.4785669164247714, "Coronavirus infection ": 52.27277024392599, "Dyslipidaemia ": 89.77957649352986, "Hypercholesterolaemia ": 53.33628903283755, "Pruritus ": 2.458791050041042, "Rash ": 3.1162971265395707, "Self-destructive behaviour ": 50.20958343048842, "Treatment noncompliance ": 10.059402853288685, "Viral load increased ": 104.16448448730864, "Weight increased ": 4.092895577177306}
\ No newline at end of file
+{"Decreased appetite": 15.524314913312612, "Hyperammonaemia": 498.2714011121074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1029.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1029.json
index 540956cfe5a..195f3869b95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1029.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1029.json
@@ -1 +1 @@
-{"Acute respiratory distress syndrome ": 2.907248433349792, "Acute respiratory failure ": 6.42624382479321, "Adenovirus infection ": 22.940543342728503, "Apnoea ": 57.086794905206126, "Apnoeic attack ": 53.88703751774717, "Asphyxia ": 2.152085770439844, "Aspiration ": 11.833684310483688, "Atelectasis ": 9.246859874464857, "Atrial septal defect ": 2.501706363876992, "Bacterial infection ": 2.467701493472656, "Body temperature decreased ": 2.173370207569456, "Bradycardia ": 2.585808935800016, "Bronchial hyperreactivity ": 16.734990816283222, "Bronchiolitis ": 795.855106221385, "Bronchitis ": 11.508968038123813, "Bronchopulmonary dysplasia ": 165.70738011159432, "Cardiac arrest ": 2.315989397374406, "Cardiac disorder ": 4.724349441298711, "Cardiac operation ": 95.26774454518748, "Cardio-respiratory arrest ": 2.4308459085667007, "Catheterisation cardiac ": 7.862698151945158, "Cerebral palsy ": 32.6368993802519, "Choking ": 2.8745433807955103, "Chronic respiratory disease ": 186.17440420032395, "Chronic respiratory failure ": 30.29644419137296, "Conjunctivitis ": 2.320389870670283, "Coronavirus infection ": 9.377845584677708, "Cough ": 5.1861043583595325, "Croup infectious ": 95.19822180250073, "Crying ": 12.579238864665786, "Cyanosis ": 17.849878465231114, "Cystic fibrosis ": 10.57188178268562, "Death ": 2.1160429983675155, "Dehydration ": 2.777474892233881, "Dermatitis diaper ": 38.7021861099303, "Developmental delay ": 3.5928155540650537, "Ear infection ": 16.310887810141697, "Electrolyte imbalance ": 2.367566494330382, "Enterovirus infection ": 64.6643884308422, "Failure to thrive ": 22.67603657821293, "Febrile convulsion ": 4.456393200026168, "Feeding disorder ": 4.40225001172453, "Fluid intake reduced ": 8.338446272164388, "Fontanelle bulging ": 90.0604154444893, "Gastroenteritis ": 10.611421096914691, "Gastroenteritis rotavirus ": 11.128835654804124, "Gastroenteritis viral ": 3.5622295088234366, "Gastrooesophageal reflux disease ": 3.5512547960246343, "Gastrostomy ": 16.171757107267304, "H1N1 influenza ": 26.584753479197943, "Heart disease congenital ": 14.403515377699994, "Hernia ": 6.27137578201339, "Hospitalisation ": 14.812632306586348, "Hydrocephalus ": 7.379805371220383, "Hypophagia ": 9.238132289677166, "Hypotonia ": 4.365242659348025, "Hypoxia ": 8.17891716182334, "Ill-defined disorder ": 3.151826655051102, "Illness ": 3.071927764491293, "Inappropriate schedule of product administration ": 2.3163840425681075, "Increased bronchial secretion ": 17.760013140355337, "Infantile spasms ": 30.43452000910176, "Infection ": 2.5192498127748544, "Influenza ": 3.18294008187578, "Inguinal hernia ": 12.191743656025077, "Irritability ": 3.815588419976157, "Lower respiratory tract infection ": 6.14019488803452, "Lung disorder ": 3.5149700029506, "Metapneumovirus infection ": 85.09869161671082, "Nasal congestion ": 8.841466414948421, "Nasopharyngitis ": 5.781711385643718, "Obstructive airways disorder ": 3.121322617869412, "Otitis media ": 25.09467310992204, "Oxygen saturation abnormal ": 11.07455627423752, "Oxygen saturation decreased ": 8.98293093621433, "Pallor ": 5.311780570315658, "Parainfluenzae virus infection ": 40.67945089811968, "Pneumonia ": 5.177931686915091, "Pneumonia aspiration ": 2.6983985035534634, "Pneumonia bacterial ": 3.4167918356732008, "Pneumonia respiratory syncytial viral ": 607.4683976830942, "Pneumonia viral ": 25.409601766476616, "Pneumothorax ": 3.628023829160131, "Poor feeding infant ": 34.438343270752696, "Product dose omission issue ": 4.635985816843809, "Pulmonary congestion ": 4.909881061699684, "Pulmonary hypertension ": 5.552956579381494, "Rales ": 3.298053290958874, "Respiration abnormal ": 4.112746645026419, "Respiratory arrest ": 5.939632004807681, "Respiratory disorder ": 10.79803298265356, "Respiratory distress ": 17.72830835778787, "Respiratory failure ": 7.963152349519801, "Respiratory rate increased ": 8.809528506131956, "Respiratory syncytial virus bronchiolitis ": 12149.277701894092, "Respiratory syncytial virus bronchitis ": 2095.93597987918, "Respiratory syncytial virus infection ": 2194.961432432083, "Respiratory syncytial virus test positive ": 4984.922324601891, "Respiratory tract congestion ": 20.37157531997831, "Respiratory tract infection ": 15.948728751093402, "Respiratory tract infection viral ": 28.712924966134054, "Rhinitis ": 6.431888217628884, "Rhinorrhoea ": 7.858839977660247, "Rhinovirus infection ": 180.1941662888103, "Rotavirus infection ": 18.476268971275363, "Secretion discharge ": 4.205386222193698, "Seizure ": 2.0681348325305278, "Selective eating disorder ": 41.05370331781002, "Staphylococcal infection ": 2.301063998896947, "Stridor ": 9.228466856804358, "Sudden death ": 4.802617068440646, "Sudden infant death syndrome ": 133.33402067364332, "Surgery ": 3.8455500331883306, "Tachypnoea ": 5.782537664633024, "Tonsillitis ": 4.117114807066312, "Tracheitis ": 36.95692845609894, "Umbilical hernia ": 8.953664599720785, "Unevaluable event ": 31.67530204354482, "Upper respiratory tract infection ": 12.008213232847556, "Upper respiratory tract inflammation ": 21.10220807567137, "Use of accessory respiratory muscles ": 85.76848509527693, "Varicella ": 2.6001533191040567, "Viral infection ": 20.80593853914922, "Viral upper respiratory tract infection ": 14.998847410228054, "Wheezing ": 9.469260714909668}
\ No newline at end of file
+{"Abdominal abscess": 4.218059667625735, "Acute hepatic failure": 3.914022727578105, "Adenocarcinoma of colon": 37.6148695725063, "Alanine aminotransferase increased": 5.307689503512639, "Alpha 1 foetoprotein increased": 8.002770564380778, "Ammonia increased": 9.495013922609548, "Anal abscess": 4.952402543059005, "Anal fistula": 6.595486222015647, "Aphonia": 2.55817137582958, "Ascites": 7.269938269043571, "Aspartate aminotransferase increased": 6.9644605263144, "Asthenia": 2.464014292878453, "Biliary obstruction": 6.794278220510165, "Bilirubin conjugated increased": 7.916564433898229, "Blister": 4.34699061045532, "Blood albumin decreased": 4.575094701203058, "Blood alkaline phosphatase increased": 2.4160293558668413, "Blood bilirubin increased": 18.143605970705973, "Blood lactate dehydrogenase increased": 2.5588509426621973, "Blood pressure increased": 2.5831125861089967, "Blood thyroid stimulating hormone increased": 5.465871739228595, "C-reactive protein increased": 2.944054792195961, "Cachexia": 3.156855688692747, "Cancer pain": 17.15482893216877, "Carbohydrate antigen 19-9 increased": 39.69305559320301, "Carcinoembryonic antigen increased": 85.28076811996347, "Cardiac dysfunction": 3.819022199562944, "Cell death": 5.177619804681565, "Cholangitis": 7.163498903841889, "Cholecystitis": 3.506593248066369, "Chromaturia": 3.289256791702419, "Colon cancer": 63.01735440490184, "Colon cancer metastatic": 91.76225954538565, "Colon cancer recurrent": 131.97498990633417, "Colorectal cancer": 20.789843672744063, "Colorectal cancer metastatic": 409.7156699371501, "Colorectal cancer recurrent": 325.45601586150894, "Colorectal cancer stage IV": 94.30195652008835, "Coma hepatic": 9.135235659397043, "Death": 2.408789695133592, "Decreased appetite": 3.9401919381728985, "Dermatitis bullous": 2.726403222348529, "Dermatitis exfoliative": 3.8163338805428335, "Dermatitis exfoliative generalised": 3.2921134231959983, "Diarrhoea": 2.4200739580385617, "Disease progression": 2.331310623178662, "Disseminated intravascular coagulation": 8.093017908698611, "Drug eruption": 7.083534351605588, "Drug-induced liver injury": 4.874594401015791, "Dry skin": 2.1585553927001384, "Duodenal perforation": 17.84452260203771, "Dysphonia": 14.28653368540536, "Eastern Cooperative Oncology Group performance status worsened": 9.22460950437574, "Eating disorder": 2.40509063864275, "Erythema multiforme": 13.90676315287218, "Faeces discoloured": 2.045355825407793, "Gastrointestinal perforation": 30.192403927791126, "Gastrointestinal stromal tumour": 29.829892794878464, "General physical health deterioration": 2.7473036898688576, "Gingival bleeding": 2.2531532524976754, "Glossitis": 2.8679538698210845, "Haemorrhage urinary tract": 3.711476793133804, "Hepatic encephalopathy": 16.78642664509995, "Hepatic failure": 8.636632298966086, "Hepatic function abnormal": 10.63835845570408, "Hepatic mass": 5.137931716152903, "Hepatitis fulminant": 7.0359841607686455, "Hepatocellular carcinoma": 17.792609847090493, "Hepatotoxicity": 5.156989869061184, "Hydronephrosis": 4.055185546224528, "Hyperammonaemia": 4.869945673019456, "Hyperbilirubinaemia": 8.973271325476142, "Hyperkeratosis": 21.792225227511054, "Hypertension": 4.748996929669808, "Hyperthermia": 2.5571918749185523, "Hypertransaminasaemia": 2.8283745600621306, "Hypoalbuminaemia": 5.612907304162706, "Hypocalcaemia": 3.3513129373358432, "Hypophagia": 2.9216083736855487, "Hypophosphataemia": 5.704116111091675, "Hypoproteinaemia": 6.983315686377209, "Hypothyroidism": 4.873288170592558, "Ileus": 5.109396343139419, "Intestinal haemorrhage": 5.545258221650082, "Intestinal obstruction": 3.6023502676312416, "Intestinal perforation": 5.331124309140023, "Jaundice": 7.761999048342339, "Jaundice cholestatic": 4.1565007985323765, "Large intestine perforation": 3.2184559359953058, "Liver disorder": 6.031307863881112, "Liver function test abnormal": 2.787069006118719, "Liver function test increased": 4.644175037317708, "Liver injury": 2.698425874431802, "Lower gastrointestinal haemorrhage": 2.869987148046988, "Lymphadenopathy mediastinal": 5.82610558980444, "Mediastinal mass": 24.471039095289207, "Melaena": 2.8155030696838548, "Metastases to abdominal cavity": 24.28542944959026, "Metastases to adrenals": 14.871516198932746, "Metastases to bone": 4.69540707373648, "Metastases to central nervous system": 10.325037494890625, "Metastases to liver": 23.874126517292257, "Metastases to lung": 38.118732324234486, "Metastases to lymph nodes": 14.775683567287034, "Metastases to pelvis": 26.880117247900117, "Metastases to peritoneum": 23.85734842534587, "Metastases to spine": 3.727047530953574, "Metastasis": 5.534298052188569, "Mouth ulceration": 3.5164763401527064, "Mucosal disorder": 3.035452100708784, "Mucosal inflammation": 9.972290900157718, "Nephrotic syndrome": 3.939537064570632, "Ocular icterus": 8.2514143042709, "Off label use": 6.924034587570523, "Oral mucosa erosion": 5.666083055556985, "Oral pain": 2.9663636300145666, "Pain of skin": 10.980126848822444, "Palmar-plantar erythrodysaesthesia syndrome": 108.34766489515604, "Palmoplantar keratoderma": 19.616636582000588, "Paronychia": 2.908198723791648, "Performance status decreased": 3.938495428818477, "Peritonitis": 4.713961807887195, "Physical deconditioning": 2.156306249538904, "Plantar erythema": 51.83478744048034, "Platelet count decreased": 8.013341828541762, "Portal hypertension": 3.245864818011414, "Posterior reversible encephalopathy syndrome": 7.168029557811422, "Pre-existing condition improved": 8.243145150574604, "Proctalgia": 5.255582445562452, "Protein urine present": 13.60207694931976, "Proteinuria": 9.854963822550864, "Pulmonary cavitation": 14.51458307726868, "Pulmonary mass": 2.998664571389495, "Rash maculo-papular": 2.8064116937230037, "Rash papular": 2.3956440412979365, "Rectal adenocarcinoma": 49.00619672516794, "Rectal cancer": 49.09719744174818, "Rectal cancer metastatic": 113.54632127258456, "Retroperitoneal lymphadenopathy": 16.280993968272302, "Secondary hypertension": 25.820594936627167, "Skin disorder": 2.6989420433026377, "Skin erosion": 3.8239177110882583, "Skin exfoliation": 9.657830387498988, "Skin fissures": 14.26684554132523, "Skin induration": 7.926535035729247, "Skin injury": 3.837779109460167, "Skin reaction": 2.5102875397970736, "Skin swelling": 7.935948615628367, "Skin toxicity": 22.68918971133137, "Skin ulcer": 4.842441244134107, "Skin warm": 2.887390944099752, "Skin weeping": 12.210612125245008, "Small intestinal perforation": 13.151896442518924, "Stevens-Johnson syndrome": 2.54660755667294, "Stoma site haemorrhage": 53.40505685373885, "Stomatitis": 6.527626139106558, "Subileus": 5.516226425844927, "Temperature intolerance": 2.4642145382163694, "Terminal state": 3.174351485649747, "Therapeutic product ineffective": 3.411395627791608, "Thrombocytopenia": 2.1173809227600966, "Toxic skin eruption": 2.683455399512715, "Transaminases increased": 3.523020840070469, "Tumour haemorrhage": 16.490273241596334, "Tumour marker increased": 16.638654375736774, "Tumour necrosis": 18.155347248931783, "Tumour pain": 14.553877713781176, "Weight decreased": 2.1320964262044164, "Yellow skin": 3.511508633704869}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/103.json
index 8ba787b6b4f..c00ba053c12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/103.json
@@ -1 +1 @@
-{"Acute kidney injury ": 14.522023002451462, "Acute respiratory distress syndrome ": 2.473225725195088, "Ageusia ": 2.181361147712342, "Agranulocytosis ": 2.004508894410474, "Aneurysm ": 11.413939234477873, "Angioedema ": 6.319003364052135, "Anuria ": 6.311806334429481, "Aplasia pure red cell ": 3.871015095206571, "Aspiration ": 8.440866362445334, "Bacteraemia ": 4.905619545794607, "Blood creatine phosphokinase increased ": 4.43351102993234, "Blood creatinine increased ": 4.451078524061699, "Blood potassium increased ": 2.980949670500079, "Blood pressure abnormal ": 3.1249498107860445, "Blood pressure fluctuation ": 4.2051086799948365, "Blood pressure inadequately controlled ": 4.672128060778976, "Blood pressure increased ": 4.769974440508845, "Blood urea increased ": 2.3483416919651763, "Blood uric acid increased ": 4.359030178857514, "Bradycardia ": 4.702164001275087, "Bundle branch block left ": 8.415815319945708, "Cardio-respiratory arrest ": 3.511940130569955, "Cardiogenic shock ": 2.287547268179808, "Cholestasis ": 2.1787190983906277, "Coma ": 2.5076808234509627, "Cutaneous vasculitis ": 11.180446097799289, "Dehydration ": 3.0396340788883616, "Dermatitis exfoliative generalised ": 5.291065492717791, "Dyspepsia ": 2.176995051876733, "Eczema ": 3.734160504931813, "Eosinophilia ": 5.604101010142409, "Erectile dysfunction ": 3.527306741030409, "Erysipelas ": 6.779553279918758, "Face oedema ": 2.664520571567422, "Fall ": 2.9190262884738365, "Gamma-glutamyltransferase increased ": 3.5165481676759587, "Hepatic cytolysis ": 7.711552929596273, "Hepatitis ": 2.614778871958837, "Hepatitis cholestatic ": 3.61523711838298, "Hyperglycaemia ": 2.458433156127104, "Hyperkalaemia ": 30.771762256957366, "Hypertension ": 3.3281757768879405, "Hypertensive crisis ": 5.691605589918321, "Hyponatraemia ": 10.222136889710535, "Hypotension ": 5.17404812914473, "Inappropriate antidiuretic hormone secretion ": 5.43385379790176, "Jaundice ": 2.692949878694765, "Lactic acidosis ": 8.858199242854303, "Laryngeal oedema ": 2.356605175196271, "Medication error ": 3.61114791705552, "Metabolic acidosis ": 3.2007463843106434, "Mitral valve incompetence ": 5.842035632098304, "Multiple organ dysfunction syndrome ": 2.0720312879652574, "Musculoskeletal chest pain ": 5.62416008711063, "Oedema peripheral ": 2.093100989706836, "Orthostatic hypotension ": 18.569821284318078, "Pancreatitis acute ": 3.834585210596814, "Pancytopenia ": 2.5663896581921195, "Photosensitivity reaction ": 2.920089833058851, "Pregnancy ": 3.847905238445936, "Product administration error ": 2.721008239155132, "Product availability issue ": 5.257459566306882, "Pulmonary arterial hypertension ": 4.593692058006757, "Rash vesicular ": 2.3163763357257543, "Renal failure ": 4.175709939851741, "Renal tubular necrosis ": 5.4779854899645, "Rhabdomyolysis ": 3.720166999893921, "Shock ": 4.864712114951386, "Subarachnoid haemorrhage ": 2.666652773030102, "Therapy non-responder ": 2.7032032773845627, "Tongue oedema ": 2.743262800664838, "Toxic skin eruption ": 2.158962104911723, "Tubulointerstitial nephritis ": 4.172706243859439, "Vasculitis ": 3.717784236531808, "Wrong patient received product ": 10.505764592652532, "Wrong product administered ": 2.118431224478702, "Wrong technique in product usage process ": 2.2827999164503976}
\ No newline at end of file
+{"Abdominal discomfort": 3.3788916737318813, "Abdominal pain upper": 2.6651898338175646, "Acquired factor V deficiency": 307.166078937283, "Adverse drug reaction": 3.930474957149952, "Adverse event": 8.225927926599862, "Alopecia": 2.3391038466101493, "Amnesia": 6.752470954741497, "Angioedema": 3.734436801483392, "Anosmia": 18.571421440031315, "Antineutrophil cytoplasmic antibody positive": 114.14688817586574, "Anxiety": 2.562712063924804, "Aortic valve stenosis": 83.88287235472347, "Arteriosclerosis": 12.279589019510942, "Arteriosclerosis coronary artery": 20.58191002661052, "Asthma": 10.182349875973024, "Atelectasis": 2.7183499123022314, "Atrial fibrillation": 5.224220318316744, "Atrial tachycardia": 186.64203289585464, "Atrial thrombosis": 10.73508685148432, "Atrioventricular block first degree": 2.7366581894904183, "Benign prostatic hyperplasia": 21.674218680067717, "Blindness": 10.354093139860606, "Blood glucose increased": 2.2999268701651547, "Blood pressure diastolic decreased": 3.760262836685236, "Blood pressure diastolic increased": 2.212541695096239, "Blood test abnormal": 74.96607308565218, "Body height decreased": 2.148871548422508, "Bronchial secretion retention": 82.83295771896186, "Bronchial wall thickening": 91.92047105923888, "Bronchiectasis": 16.767859443156183, "Bronchopulmonary aspergillosis allergic": 24.58117118550698, "Burning sensation": 12.925521378678692, "Cardiac amyloidosis": 13.257791101702876, "Cardiac disorder": 11.149650008815064, "Cardiac failure chronic": 3.352653791939769, "Cardiac failure congestive": 2.534364416670424, "Cardiospasm": 1656.455825694076, "Carotid artery occlusion": 136.0551387464494, "Carpal tunnel syndrome": 91.26460706939746, "Cerebral thrombosis": 3.507197320821388, "Cerebral venous sinus thrombosis": 2.410639255740828, "Chest X-ray abnormal": 18.356667918816942, "Chronic sinusitis": 2.534285766969956, "Coagulation factor V level abnormal": 212.5544576941761, "Coagulation factor deficiency": 132.652584400636, 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"Fibromyalgia": 28.533907040667657, "Forced expiratory volume decreased": 42.578949522765285, "Full blood count abnormal": 22.627245272351654, "Gastrooesophageal reflux disease": 14.084752043305244, "Gout": 6.940674305772917, "Haemoptysis": 6.018607878443826, "Haemorrhage intracranial": 2.135358699659514, "Hallucination": 3.9996870601302654, "Heart rate increased": 3.223246548292053, "Hepatic lesion": 6.530851119727518, "Hospitalisation": 5.1486048875940025, "Human rhinovirus test positive": 62.17220658164793, "Hypertension": 3.8126757844309673, "Hypoacusis": 3.2317399542383733, "Hypothyroidism": 17.1716546478448, "Hypoxia": 4.758532708692389, "Immunisation": 2.673677519431933, "Infective exacerbation of chronic obstructive airways disease": 219.76731271539452, "Infusion site erythema": 2.503542633395959, "Insomnia": 2.4298459552987346, "Intentional product misuse": 3.092755092049531, "Intentional product use issue": 6.219011474160773, "Intervertebral disc degeneration": 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"Pulmonary vasculitis": 98.64336981947288, "Renal disorder": 18.368528666298804, "Renal mass": 16.573163253191524, "Respiratory symptom": 5.473447712300132, "Respiratory syncytial virus test positive": 15.402543134457806, "Rhinitis allergic": 113.38250694989956, "Rhinorrhoea": 3.9667844266015866, "Right atrial hypertrophy": 290.1765638991612, "Right ventricular hypertrophy": 29.40522693554893, "Sensitisation": 774.829817809709, "Sinus rhythm": 8.766405632671173, "Sleep apnoea syndrome": 66.38592779086599, "Sleep disorder due to a general medical condition": 64.73068932169508, "Sleep disorder due to general medical condition, insomnia type": 18.42533342017377, "Sleep terror": 13.283675651103362, "Small intestinal obstruction": 4.705964938045093, "Snoring": 2.147594334252728, "Spirometry abnormal": 50.31116994589158, "Subarachnoid haemorrhage": 6.917929117735066, "Superficial vein thrombosis": 2.296454018113001, "Suspected suicide": 8.227768495691603, "Tachyarrhythmia": 64.17304634885492, "Tension headache": 2.7383918961741798, "Therapeutic product effect incomplete": 11.18146364286868, "Troponin T increased": 4.704933921260735, "Vascular pseudoaneurysm": 5.441826841944586, "Vasculitis": 2.654220449459224, "Ventricular arrhythmia": 4.162451003558801, "Ventricular tachycardia": 2.662107977242554, "Wheezing": 12.86555793013557, "Wound haemorrhage": 2.6832565421810672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1030.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1030.json
index 59dabc41a79..cc5e0519f0f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1030.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1030.json
@@ -1 +1 @@
-{"Bronchiolitis ": 779.166294388646, "Bronchitis ": 12.84332727274147, "Cough ": 3.714649392294732, "Crying ": 9.760082668090943, "Cyanosis ": 15.050539805386926, "Febrile convulsion ": 104.2446634797766, "Gait disturbance ": 2.308275650073966, "Gastroenteritis ": 49.50427881908052, "Hypotonia ": 15.496026164217271, "Hypotonic-hyporesponsive episode ": 157.4062306832819, "Nasopharyngitis ": 5.439428078260963, "Otitis media ": 171.24733030314465, "Pharyngitis ": 41.241806972258544, "Pharyngotonsillitis ": 1141.1071288927312, "Pneumonia ": 2.5341077722995995, "Pyrexia ": 3.21711157386507, "Rhinorrhoea ": 6.683469626978567, "Seizure ": 2.5738113434731185, "Tonsillitis ": 50.87302756135354, "Upper respiratory tract infection ": 36.55224574583768}
\ No newline at end of file
+{"Abortion induced": 55.492594492243846, "Alanine aminotransferase increased": 3.564923615819831, "Blood alkaline phosphatase increased": 10.51552654387456, "Drug interaction": 3.5488844248817992, "Gamma-glutamyltransferase increased": 13.98440149259873, "Gynaecomastia": 32.00288477148004, "Hepatic function abnormal": 6.044500916883304, "Immune reconstitution inflammatory syndrome": 50.74421148408263, "Insomnia": 2.223301781918884, "Liver injury": 11.968814558743084, "Overdose": 2.905313149425483, "Platelet count decreased": 2.614785858600858, "Pregnancy": 36.640987519026496, "Pruritus": 2.45016771698168, "Rash": 6.467424469518315, "Suicide attempt": 5.525759789595508, "Toxic skin eruption": 23.007443378207885, "Transaminases increased": 8.51162050351136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1031.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1031.json
index 7d3acfcb1ec..4d6d8b7d52e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1031.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1031.json
@@ -1 +1 @@
-{"Acute graft versus host disease ": 9.556973829554424, "Acute kidney injury ": 4.632972201997329, "Aplasia pure red cell ": 9.435409341152765, "Aspergillus infection ": 13.91952464524402, "Bacterial infection ": 4.539085156493998, "Blood creatinine increased ": 3.813735773258565, "Blood magnesium decreased ": 14.473511721623495, "Bronchopulmonary aspergillosis ": 15.253063593946726, "Candida infection ": 13.267752348376414, "Complications of transplanted kidney ": 74.50705244939448, "Contraindicated product administered ": 2.7845585326378406, "Cytomegalovirus infection ": 15.157237278663734, "Cytomegalovirus infection reactivation ": 11.550805057576676, "Cytomegalovirus viraemia ": 20.03520013050089, "Delirium ": 3.1871101315817185, "Diffuse large B-cell lymphoma ": 9.65208618744716, "Drug interaction ": 15.81470973551902, "Drug level below therapeutic ": 20.324218023469687, "Drug level decreased ": 20.65286278363047, "Drug level increased ": 28.988626951777054, "Drug-induced liver injury ": 2.439295289009844, "Electrocardiogram QT prolonged ": 3.153313608304094, "Electrolyte imbalance ": 11.05953188385152, "Encephalopathy ": 3.0534522890184603, "Epstein-Barr virus infection ": 14.84013748743892, "Foetal exposure during pregnancy ": 2.2210328204057324, "Fungal infection ": 6.374138011007898, "Gastric ulcer ": 3.836088753065124, "Graft versus host disease ": 26.73033623851588, "Graft versus host disease in gastrointestinal tract ": 27.46189931928016, "Hepatotoxicity ": 2.315869496282281, "Hiccups ": 7.0034951531256535, "Hyperkalaemia ": 9.20247570669359, "Immunosuppressant drug level decreased ": 248.0418648889223, "Immunosuppressant drug level increased ": 264.6432124536741, "Kidney transplant rejection ": 43.66762927488129, "Labelled drug-drug interaction medication error ": 8.395399340523921, "Leukopenia ": 2.2104064797681637, "Liver transplant rejection ": 108.23083641779152, "Mental status changes ": 4.740266931794532, "Multiple organ dysfunction syndrome ": 2.2936034813393302, "Nephropathy toxic ": 26.15257354673421, "Neurotoxicity ": 11.378608573956864, "Nocardiosis ": 66.56801510090207, "Oesophageal candidiasis ": 15.158382280624116, "Off label use ": 2.29665066997234, "Peritonitis ": 9.178477286389231, "Polyomavirus-associated nephropathy ": 70.68430142199296, "Post transplant lymphoproliferative disorder ": 23.09285420269395, "Posterior reversible encephalopathy syndrome ": 13.802264725416752, "Premature baby ": 6.992214468985721, "Premature delivery ": 3.789818494331719, "Renal impairment ": 4.091469548624541, "Renal tubular necrosis ": 6.980908071945522, "Respiratory failure ": 2.017375804077936, "Scedosporium infection ": 118.72095024196096, "Septic shock ": 2.38036609686691, "Skin lesion ": 3.007428543531706, "Squamous cell carcinoma of skin ": 21.68212317763691, "Staphylococcal infection ": 3.4611760965196705, "Thrombotic microangiopathy ": 24.854055910318632, "Toxicity to various agents ": 4.897400962091449, "Transplant rejection ": 48.36680142436104, "Tuberculosis ": 7.325966222814844, "Varicella zoster virus infection ": 22.159620992696937}
\ No newline at end of file
+{"Acute kidney injury": 3.837093010245585, "Adrenal suppression": 6.897087185349649, "Anhedonia": 37.93305612535252, "Ankle fracture": 16.419407186686197, "Anxiety": 9.74465712378995, "Blood HIV RNA increased": 8.017341240353831, "Blood creatine increased": 3.9269584221099176, "Blood creatinine abnormal": 7.6005497975066785, "Blood creatinine increased": 6.959423137482869, "Blood phosphorus decreased": 3.7996629517840974, "Bone cyst": 12.0161605234461, "Bone demineralisation": 39.78471389191874, "Bone density abnormal": 44.9800487963953, "Bone density decreased": 41.367314904971614, "Bone disorder": 9.567419231356164, "Bone loss": 44.070120219291205, "CD4 lymphocytes decreased": 7.833713108836502, "Cervical vertebral fracture": 4.16721827273374, "Chronic kidney disease": 29.96502828292687, "Chronic kidney disease-mineral and bone disorder": 14.579060174187846, "Clavicle fracture": 11.025723719402247, "Compression fracture": 5.807050585340042, "Craniofacial fracture": 5.086296515270692, "Decreased activity": 8.72562595648275, "Degenerative bone disease": 38.18806742020685, "Dental caries": 4.099300429734812, "Depression": 2.185897463030438, "Drug resistance": 2.2244384333546305, "Dysstasia": 4.082773270989218, "Economic problem": 47.41659546093008, "Emotional distress": 31.391290817044823, "End stage renal disease": 13.156522103308722, "Fanconi syndrome": 6.001312126304554, "Fanconi syndrome acquired": 17.07001337853639, "Fear-related avoidance of activities": 44.68238171689551, "Femur fracture": 4.241734620439612, "Fibula fracture": 11.484953535141832, "Foot fracture": 13.093899613779907, "Fracture": 24.913703256263304, "Fractured coccyx": 7.70458096946798, "Gene mutation identification test positive": 16.558650560064695, "Genotype drug resistance test positive": 10.881243385437315, "Glomerular filtration rate abnormal": 19.99977407824438, "Glomerular filtration rate decreased": 7.059146965188791, "Glomerular filtration rate increased": 11.120092820898366, "HIV test positive": 8.126243426562583, "Hand fracture": 22.87269317018801, "Hepatitis B": 2.094615756278807, "Hip arthroplasty": 6.665369088413817, "Hip fracture": 5.156764603971011, "Hip surgery": 3.8955786074570313, "Humerus fracture": 3.2049474000090923, "Immune reconstitution inflammatory syndrome": 3.661143387132785, "Impaired work ability": 2.0435730049528598, "Intervertebral disc degeneration": 6.914664223853307, "Jaw fracture": 9.851149821781922, "Loss of personal independence in daily activities": 2.9151883326726065, "Lower limb fracture": 6.724854728671521, "Meniscus injury": 2.8838998318480638, "Multiple fractures": 39.76729575086082, "Nephrolithiasis": 3.558028936981078, "Nephropathy": 14.935658524312323, "Nephropathy toxic": 16.302223077865932, "Osteoarthritis": 4.125715809934811, "Osteochondrosis": 9.733075617096606, "Osteomalacia": 15.30060678883252, "Osteonecrosis": 40.16079280889993, "Osteopenia": 31.278487027827527, "Osteoporosis": 31.576430709141217, "Osteoporotic fracture": 4.512159499609686, "Pain": 4.357722095545041, "Patella fracture": 4.065729447325782, "Pathological fracture": 5.419408444349534, "Pelvic fracture": 2.0078561174450296, "Post-traumatic stress disorder": 4.149638767731106, "Protein total abnormal": 38.08103452661691, "Protein total increased": 16.158653148413833, "Protein urine present": 12.203197917789748, "Proteinuria": 4.7347056716076406, "Quality of life decreased": 8.731561370371342, "Radius fracture": 5.277221955770337, "Renal cyst": 2.4887361267350983, "Renal failure": 16.00421654754964, "Renal impairment": 5.999427301353714, "Renal injury": 25.85561510833812, "Renal tubular disorder": 5.482068065821315, "Renal tubular dysfunction": 5.2914957233283, "Renal tubular necrosis": 2.957742685840929, "Rib fracture": 12.038808566425972, "Shoulder fracture": 7.770960339319937, "Skeletal injury": 24.51679949132032, "Spinal compression fracture": 8.189066809692145, "Spinal disorder": 3.0617460029340062, "Spinal fracture": 9.637133745949392, "Spinal osteoarthritis": 8.63799507832165, "Spinal stenosis": 3.0833051558831768, "Spondylolisthesis": 11.455756623183191, "Stress fracture": 8.399935519389151, "Teeth brittle": 23.07609301873647, "Thoracic vertebral fracture": 3.348862490082252, "Tibia fracture": 10.712464721935309, "Toe amputation": 2.4233715198134385, "Tooth disorder": 3.680807680656984, "Tooth extraction": 5.042597811637255, "Tooth fracture": 21.65263019670649, "Tooth loss": 36.9627791881238, "Ulna fracture": 12.727599742554318, "Upper limb fracture": 6.600377437949353, "Vertebral foraminal stenosis": 22.88510668025476, "Viral load increased": 9.588219359523416, "Viral mutation identified": 7.4161622485859, "Virologic failure": 8.415654762306158, "Vitamin D decreased": 5.153770237075881, "Vitamin D deficiency": 14.623116481880254, "Walking aid user": 4.229195771901956, "Wrist fracture": 12.41062327368115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1032.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1032.json
index f486ce2730b..a30b6da9d02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1032.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1032.json
@@ -1 +1 @@
-{"Basal cell carcinoma ": 45.30284295792817, "Blood pressure increased ": 2.6807718043003, "Cardiac failure ": 6.524093131772856, "Drug interaction ": 2.4814046230106723, "Malignant melanoma ": 27.122319976752102, "Respiratory syncytial virus infection ": 47.11616481082915, "Toxicity to various agents ": 3.4816910427180288}
\ No newline at end of file
+{"Abnormal behaviour": 2.261691333626838, "Abortion induced": 10.19387658775518, "Abortion spontaneous": 13.990258219744732, "Abscess limb": 2.8443402403582376, "Accident": 6.761878589114699, "Accident at work": 9.392615948315417, "Accidental exposure to product": 5.538336475743187, "Accidental exposure to product by child": 51.655873590722585, "Accidental overdose": 3.906658058374752, "Acute hepatitis C": 29.49043047496476, "Adverse event": 3.933580020803972, "Affective disorder": 2.541486461107473, "Agitation neonatal": 28.31181249799493, "Alcohol abuse": 50.48731469270317, "Alcohol poisoning": 2.7883742421276456, "Alcohol withdrawal syndrome": 13.517819895565216, "Alcoholism": 13.524105551343228, "Amniotic cavity infection": 11.132558882060517, "Amniotic fluid volume decreased": 16.06504125506405, "Anaemia of pregnancy": 94.80203619700433, "Anger": 2.00119379478964, "Ankle fracture": 3.0492857990740463, "Anxiety": 2.198267808490067, "Appendicitis perforated": 4.789006577684701, "Appendix disorder": 15.235203674969052, "Arteritis": 8.110760571375518, "Arthritis infective": 2.4928157894274574, "Attention deficit hyperactivity disorder": 5.868751159677377, "Back disorder": 4.938935903990725, "Back injury": 2.53145509271739, "Behaviour disorder": 2.2192745103184963, "Bipolar disorder": 2.6545360872009467, "Blood testosterone decreased": 7.849910944851148, "Borderline personality disorder": 17.018454858481338, "Bradycardia foetal": 4.459699629593513, "Brain injury": 5.360006017786394, "Cardiac hypertrophy": 6.242236960907431, "Cerebral disorder": 3.3884476170113964, "Child neglect": 116.89590583265442, "Cleft palate": 2.6078336283527324, "Complication of pregnancy": 12.301752687092277, "Concussion": 3.8670255307034016, "Congenital anomaly": 3.179137207643681, "Craniocerebral injury": 3.088171354250926, "Craniofacial fracture": 7.369881373297337, "Crying": 2.9999084818954165, "Dental caries": 12.260222937451568, "Dependence": 8.94771372074494, "Depression": 2.891054843557347, "Detoxification": 86.20751176039343, "Developmental delay": 7.58536031568013, "Developmental hip dysplasia": 7.320066583805854, "Disability": 4.503276277195378, "Drug abuse": 12.365476970842847, "Drug dependence": 19.691327967674003, "Drug detoxification": 391.71877846177904, "Drug diversion": 58.925001048524685, "Drug effect less than expected": 12.662211326013413, "Drug ineffective for unapproved indication": 3.0743330884391864, "Drug level fluctuating": 12.9093054610857, "Drug screen negative": 237.63185643055596, "Drug screen positive": 31.26446222108259, "Drug withdrawal convulsions": 5.4316405022887375, "Drug withdrawal syndrome": 61.85572902319647, "Drug withdrawal syndrome neonatal": 141.42027231905917, "Ectopic pregnancy": 3.814687570136633, "Endocarditis": 7.489962753352056, "Energy increased": 8.182732758732588, "Euphoric mood": 17.900787673624606, "Exposure during pregnancy": 10.919153075500306, "Exposure via breast milk": 54.03878760027632, "Extra dose administered": 3.0099091121428674, "Facial asymmetry": 6.60045239718795, "Failure to thrive": 5.414195948183034, "Feeling abnormal": 2.817944245046508, "Feeling guilty": 12.732692712441128, "Feeling jittery": 2.551223370767334, "Feeling of body temperature change": 5.806096060797016, "Feeling of despair": 2.191718495826146, "Fever neonatal": 41.475511394527175, "Fibula fracture": 5.897810484915893, "Foaming at mouth": 3.329928055283052, "Foetal distress syndrome": 7.34344764637757, "Foetal exposure during pregnancy": 24.324548621955607, "Foetal exposure via father": 88.01753734723852, "Foetal growth restriction": 6.464882274430163, "Foetal heart rate abnormal": 7.182301574836217, "Foetal heart rate decreased": 15.16748516887113, "Foetal hypokinesia": 18.150206566778685, "Foot fracture": 2.93222341937481, "Formication": 2.8235380024702352, "Gallbladder disorder": 6.179151297682488, "Gestational diabetes": 6.122302551536591, "Gestational hypertension": 16.514168120873606, "Gingival disorder": 2.8140812955514574, "Gun shot wound": 37.68862266788788, "Hallucination": 3.2099788917627228, "Hallucination, auditory": 4.223094164518433, "Hallucination, visual": 2.739438946138125, "Hand fracture": 3.000795013379057, "Head circumference abnormal": 40.79009719040551, "Head injury": 2.8682635646402423, "Heart disease congenital": 3.264566365973748, "Hepatic pain": 3.449977908525622, "Hepatitis C": 6.472257077760794, "High risk pregnancy": 51.0787967590382, "Homicidal ideation": 5.45247566682297, "Homicide": 14.887875735121906, "Hospitalisation": 5.326733779176508, "Hyperbilirubinaemia neonatal": 16.185445036888865, "Hypertensive heart disease": 3.593636930279242, "Hypoglycaemia neonatal": 7.794184723736071, "Hypopnoea": 2.940472907760595, "Illness": 2.016725912078749, "Impaired driving ability": 9.260959615908895, "Inadequate analgesia": 8.553122753013692, "Inappropriate schedule of product administration": 4.856118573383995, "Inappropriate schedule of product discontinuation": 170.134754859374, "Incoherent": 2.915550746623422, "Incorrect route of product administration": 2.0721780577005378, "Infantile colic": 175.204627579188, "Infantile diarrhoea": 68.77082860541636, "Infantile vomiting": 17.595149349726622, "Injection site abscess": 4.117068561323337, "Injection site necrosis": 3.434237309252293, "Insomnia": 2.4161013529667863, "Intentional product misuse": 6.232903123987146, "Intentional product use issue": 5.533815306201888, "Intentional underdose": 213.18254319836905, "Intervertebral disc degeneration": 2.796652675646357, "Intervertebral disc disorder": 3.106924135520205, "Intervertebral disc protrusion": 3.641716992925165, "Irritability": 2.8227561808396064, "Jaundice neonatal": 80.40526902862044, "Jaw fracture": 5.823970950528313, "Joint injury": 4.029592961071299, "Knee deformity": 7.416324534699641, "Learning disability": 17.15947908300515, "Libido decreased": 3.7426425403829593, "Ligament rupture": 3.63030183991497, "Limb crushing injury": 19.797505479845285, "Limb injury": 3.5475267648876327, "Lip and/or oral cavity cancer": 12.68299216640684, "Loss of consciousness": 2.617900345277252, "Loss of employment": 3.0587261210794163, "Low birth weight baby": 20.40385391068085, "Lower limb fracture": 3.7590065006657714, "Macrosomia": 28.74245677671753, "Major depression": 4.833808813131921, "Maternal exposure during pregnancy": 8.588514981423115, "Meconium aspiration syndrome": 62.30094742518276, "Meconium stain": 33.18238277641164, "Medical observation": 60.93380293075059, "Mental disorder": 4.072150954830946, "Mental impairment": 2.211060442677512, "Miosis": 4.720513059383187, "Multiple cardiac defects": 62.21856163151718, "Multiple congenital abnormalities": 3.3338876533368818, "Nasal septal operation": 86.29154471428319, "Neck injury": 8.733245554775625, "Neonatal aspiration": 55.03428367824255, "Neonatal disorder": 48.6696527338376, "Neonatal respiratory distress": 10.414364546775122, "Neonatal respiratory distress syndrome": 10.154045924692598, "Neonatal seizure": 20.164969480864585, "Nerve compression": 4.50293383839562, "Nerve injury": 2.3012144959134653, "No adverse event": 2.319018645205738, "Ocular icterus": 2.5440398806498683, "Oligohydramnios": 6.366040991467552, "Oral administration complication": 64.06731827663016, "Ovarian cyst": 2.2386792417100123, "Overdose": 6.697916695121059, "Overweight": 4.170405452496121, "Pain threshold decreased": 165.48324128422408, "Pancreatitis chronic": 2.4179600483307486, "Panic attack": 2.888542838445511, "Paranoia": 7.139590069125695, "Paternal exposure during pregnancy": 14.7829858931814, "Personal relationship issue": 8.72415631240863, "Pharyngeal swelling": 4.073687752251192, "Physical assault": 8.062619897563344, "Piloerection": 5.515729708118398, "Placenta praevia": 21.27051078674856, "Poor feeding infant": 26.639278099879466, "Poor sucking reflex": 12.63788076750332, "Poor weight gain neonatal": 76.54748509727662, "Post-traumatic stress disorder": 5.350373633738211, "Postpartum haemorrhage": 8.780104020573138, "Pre-eclampsia": 10.712903288733242, "Pre-existing condition improved": 3.794540152470388, "Premature baby": 12.612305107115532, "Premature delivery": 25.87609419684661, "Premature labour": 24.616421498791208, "Premature rupture of membranes": 8.098139334715492, "Premature separation of placenta": 13.206352350209208, "Prescribed overdose": 4.142519512561109, "Priapism": 2.591233594320881, "Procedural pain": 13.969368258522453, "Product dose omission in error": 2.0031607521007544, "Product preparation issue": 321.29017703116045, "Product prescribing error": 2.2503529369889703, "Product use issue": 3.362767992288925, "Psychomotor hyperactivity": 4.977229960777053, "Psychotic disorder": 2.4895023808653653, "Psychotic symptom": 5.134542508350255, "Reading disorder": 10.20428945040482, "Respiratory arrest": 2.004328676138488, "Respiratory depression": 6.121845755922591, "Respiratory disorder neonatal": 10.604332462773012, "Respiratory rate decreased": 2.0823832776314752, "Restless legs syndrome": 2.4325764990381638, "Restlessness": 2.5983832599891765, "Rib fracture": 5.799742982182621, "Road traffic accident": 14.88204689025024, "Seizure": 2.557123529439152, "Selective abortion": 65.30087065203118, "Selective eating disorder": 40.35611551603176, "Shoulder fracture": 2.139143321509044, "Skin laceration": 2.763226275155497, "Skull fracture": 8.289863718694649, "Sleep apnoea syndrome": 4.187819352751132, "Small for dates baby": 8.648944759472482, "Sneezing": 3.5516594507302908, "Social anxiety disorder": 7.535229397030182, "Speech disorder developmental": 6.974792737623972, "Spinal fracture": 3.1651449991164777, "Stillbirth": 6.489291769133408, "Substance abuse": 110.84004521298532, "Substance dependence": 9.865783295530507, "Substance use disorder": 8.270914328273994, "Sudden infant death syndrome": 15.34483005700388, "Suicidal behaviour": 2.626063020500449, "Suicidal ideation": 5.374012912824218, "Swollen tongue": 2.311744953637295, "Tachyphrenia": 7.392749448485248, "Talipes": 3.210084138230469, "Testis cancer": 3.000535786984568, "Tethered oral tissue": 22.256054113152867, "Theft": 26.88118075796904, "Therapeutic product ineffective": 18.0947818536596, "Therapeutic response unexpected": 5.337495060274434, "Therapy interrupted": 14.148756790127305, "Therapy naive": 241.7446505356844, "Throat cancer": 3.4690739238878985, "Tibia fracture": 3.257640761404787, "Tooth disorder": 5.24015540242561, "Tooth erosion": 14.66997546059472, "Tooth fracture": 3.708215364821258, "Toothache": 2.449941469030418, "Toxicity to various agents": 4.152196215821857, "Transient tachypnoea of the newborn": 15.911441040586269, "Tremor neonatal": 75.9909684232489, "Trisomy 21": 6.758648035625473, "Umbilical cord abnormality": 14.4442909842514, "Underdose": 11.48629903903368, "Unevaluable event": 3.337937939813196, "Unresponsive to stimuli": 4.270361095029879, "Upper limb fracture": 4.540615718426159, "Uterine disorder": 16.933909194533, "Victim of abuse": 65.31846355589512, "Victim of crime": 76.68994418069478, "Victim of sexual abuse": 36.79064168628207, "Vomiting projectile": 5.692177140957735, "Vulvovaginal candidiasis": 2.4830436304019723, "Weight decrease neonatal": 72.53584469045063, "Withdrawal syndrome": 7.575617853240657, "Wrist fracture": 2.803733551072662, "Wrong technique in product usage process": 8.220959771224596, "Yawning": 9.518443367766004}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1033.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1033.json
index 76de3ff6296..2501945a9b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1033.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1033.json
@@ -1 +1 @@
-{"Acute kidney injury ": 6.895030961377874, "Cardiac failure ": 15.080049937098195, "Dyspnoea ": 2.0852597649905174, "Syncope ": 8.648635389357425}
\ No newline at end of file
+{"Amnesia": 58.49653583304914, "Anxiety": 2.5182975219052115, "Chemical submission": 19458.108500057097, "Drug abuse": 86.9809708477372, "Drug dependence": 7.616059680106968, "Injection": 13466.474301417627, "Loss of consciousness": 4.456619762196874, "Somnolence": 3.336453482080453, "Substance abuse": 39.7798324017028, "Vomiting": 2.04686078547525}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1034.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1034.json
index 5fa98d7516e..51bb4666259 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1034.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1034.json
@@ -1 +1 @@
-{"Asthenia ": 2.0298473465254023, "Cardiac failure ": 2.1328680971681124, "Death ": 6.644593702886772, "Disease progression ": 2.428502090800721, "Dysphagia ": 5.337199756249735, "General physical health deterioration ": 2.256908028393501, "Hospitalisation ": 3.607536407949742, "Hyperkeratosis ": 31.339646439611634, "Hyperpyrexia ": 16.748828454881412, "Malignant melanoma ": 26.51803200313268, "Malignant neoplasm progression ": 10.074603566996371, "Metastases to central nervous system ": 35.97684734159338, "Metastases to lung ": 10.738587887181808, "Metastatic malignant melanoma ": 127.91629892137396, "Neutropenia ": 2.019760512205349, "Palmoplantar keratoderma ": 337.1039155598279, "Product use in unapproved indication ": 2.324612050438269, "Pyrexia ": 3.2417323990065148, "Skin papilloma ": 56.4605016308825, "Uveitis ": 33.144610733618265}
\ No newline at end of file
+{"Acute generalised exanthematous pustulosis": 7.403251602720803, "Acute pulmonary oedema": 8.897214010958006, "Acute respiratory distress syndrome": 4.355654829220852, "Allergy test negative": 186.1501833360041, "Anaesthetic complication": 65.0873203784674, "Anaesthetic complication neurological": 893.9317810214162, "Anaphylactic reaction": 16.491298678692914, "Anaphylactic shock": 109.9967214958737, "Anaphylactoid reaction": 19.71177305225272, "Anaphylactoid shock": 212.05232038263395, "Apnoea": 3.863862385315131, "Atrioventricular block": 7.754753396190877, "Blood pressure decreased": 4.480719009294605, "Bradycardia": 6.111009571809047, "Bradypnoea": 12.13644301079264, "Bronchospasm": 67.14935774584228, "Bronchospasm paradoxical": 74.50156901244907, "Cardiac arrest": 12.445443274570842, "Cardio-respiratory arrest": 11.00704668139615, "Cardiogenic shock": 7.741719728053575, "Cholestasis": 6.9087089196938845, "Circulatory collapse": 15.04516960572782, "Coma": 2.6877120496775144, "Conjunctivitis": 4.023517925245391, "Cyanosis": 3.113441726415781, "Eosinophilia": 6.226639698414206, "Erythema": 7.066878871803732, "Exposure during pregnancy": 3.6708429368905486, "Gastritis": 3.1270129199642613, "Haemodynamic instability": 18.45473884285001, "Hemiplegia": 4.1239994903891946, "Hepatic cytolysis": 7.54066673128345, "Histamine level increased": 233.4923689841373, "Horner's syndrome": 157.79323117684072, "Hypersensitivity": 2.066344387904365, "Hyperthermia malignant": 133.87630810898844, "Hypotension": 15.765911032941878, "Hypotonia": 3.0338722906143767, "Hypoxia": 4.237604610999548, "Inadequate analgesia": 40.11323721734267, "Incorrect route of product administration": 2.829203323601296, "Laryngospasm": 9.679819183490704, "Macule": 19.15446590647125, "Maternal exposure during delivery": 66.73311128693486, "Maternal exposure during pregnancy": 3.148377370358524, "Miosis": 9.856369291838975, "Myoclonus": 5.079150875332176, "Neuromuscular blockade": 151.23454294364646, "Normal newborn": 9.741556511994713, "Oxygen saturation decreased": 4.890130986763746, "Paraparesis": 15.96645380539012, "Pneumonia aspiration": 5.033002883227971, "Pneumothorax": 3.622375758224646, "Postoperative delirium": 809.6657414852194, "Premature baby": 2.173504966771082, "Procedural hypotension": 104.79014404852744, "Radiculopathy": 5.971469817310013, "Rash": 2.5161434758775045, "Rash maculo-papular": 4.735983068484234, "Rash morbilliform": 4.77817246800226, "Respiratory arrest": 3.5092173992090943, "Respiratory depression": 21.54729923188729, "Sedation": 4.0074381768675975, "Sedation complication": 10.832595028660094, "Shock": 22.7803855869522, "Shock haemorrhagic": 4.612095962920212, "Stress cardiomyopathy": 34.463940685367675, "Tachycardia": 6.671906180203018, "Toxic epidermal necrolysis": 2.765564380201957, "Toxic skin eruption": 5.716324515093811, "Type I hypersensitivity": 50.08235675337304, "Urinary incontinence": 2.5027041985782965, "Urticaria": 4.307469041577118, "Ventricular extrasystoles": 4.634709394888435, "Ventricular tachycardia": 2.9120515816660024, "Withdrawal syndrome": 2.6950279545415987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1035.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1035.json
index 28391ada183..98cc728af72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1035.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1035.json
@@ -1 +1 @@
-{"Acne ": 3.9817893001292526, "Acquired gene mutation ": 14.86060427971434, "Aplastic anaemia ": 2.4584023089024867, "Atelectasis ": 2.37771660757051, "Blood creatine phosphokinase increased ": 2.6123542299220905, "Blood sodium decreased ": 2.0135075514031517, "Body height decreased ": 4.185769001700461, "Brain neoplasm ": 6.644883522038496, "Brain oedema ": 3.1302435548088, "Carcinoembryonic antigen increased ": 42.61673227311675, "Cardiac dysfunction ": 12.327542922884517, "Cardiac failure ": 8.521493177010159, "Cardiac failure acute ": 5.251452961857661, "Cardiac failure chronic ": 3.822153430360925, "Cardiac failure congestive ": 2.5075023229947604, "Cardiac tamponade ": 5.463955370606241, "Cardiomyopathy ": 5.997049806132496, "Cardiotoxicity ": 4.967330641045299, "Cerebral infarction ": 3.4034875300558856, "Conjunctivitis ": 2.064826211216725, "Cutaneous vasculitis ": 3.395635663936643, "Decreased appetite ": 3.320458532718724, "Deep vein thrombosis ": 2.185114127131098, "Dermatitis ": 3.846071887202495, "Dermatitis acneiform ": 23.26756462073814, "Diarrhoea ": 3.4768139923517114, "Dilated cardiomyopathy ": 3.147025142157053, "Disease progression ": 2.480300105556443, "Drug eruption ": 2.929434774742854, "Drug resistance ": 4.47367629226466, "Dry eye ": 2.448772686386256, "Dry skin ": 9.05282648504712, "EGFR gene mutation ": 44.62231329418593, "Ejection fraction decreased ": 11.295137675058209, "Electrocardiogram QT prolonged ": 14.629520935685772, "Erythema multiforme ": 5.641609336630526, "Feeding disorder ": 3.094787333093971, "Femur fracture ": 2.416476449857122, "Fracture ": 2.645747600499752, "Haematotoxicity ": 2.965636279316429, "Haemoptysis ": 2.417693027600344, "Heart failure with reduced ejection fraction ": 28.31332695155776, "Hepatic function abnormal ": 2.429688221568133, "Hypophagia ": 2.2703870435921254, "Interstitial lung disease ": 47.55755804580372, "Keratitis ": 19.58168248049645, "Liver disorder ": 3.2453349166959704, "Long QT syndrome ": 15.736520794768186, "Lung disorder ": 8.477348622658056, "Lung infiltration ": 2.1073581419576777, "Lung neoplasm malignant ": 8.157281600255411, "Lung opacity ": 22.832835082362784, "Lymphangiosis carcinomatosa ": 54.89363797859607, "Malignant neoplasm progression ": 23.07686060217942, "Malignant pleural effusion ": 16.791500949232315, "Metastases to bone ": 16.023886140613364, "Metastases to central nervous system ": 50.12358179331599, "Metastases to liver ": 7.575937267365127, "Metastases to lung ": 6.587186732999116, "Metastases to lymph nodes ": 7.505266377899103, "Metastases to meninges ": 80.14189619352831, "Metastases to pleura ": 27.48685934398338, "Metastases to spine ": 15.279311033087652, "Metastasis ": 19.640796287052037, "Mouth ulceration ": 2.0692533413201595, "Mucosal disorder ": 6.642481227070001, "Mucosal inflammation ": 3.283513389119108, "Myelosuppression ": 2.6984300502336844, "Nail bed inflammation ": 116.04007033133642, "Nail disorder ": 27.50616212964865, "Neoplasm progression ": 2.3573911721813654, "Neutrophil count decreased ": 2.1104475114733785, "No adverse event ": 2.7729909872459397, "Non-small cell lung cancer ": 11.60562978054623, "Onychoclasis ": 37.42974064973691, "Paronychia ": 140.35659557675618, "Pericardial effusion ": 3.709610246804262, "Platelet count decreased ": 4.392614564417044, "Pleural effusion ": 10.054866459723204, "Pneumocystis jirovecii pneumonia ": 2.552700740824178, "Pneumonia aspiration ": 2.26254680295525, "Pneumonia bacterial ": 8.470957817758496, "Pneumonitis ": 41.91260667605256, "Pneumothorax ": 6.265809169077893, "Pulmonary alveolar haemorrhage ": 4.041715289510191, "Pulmonary embolism ": 3.061761150380486, "Pulmonary mass ": 2.911086503171793, "Pulmonary oedema ": 2.745842825195677, "Pulmonary toxicity ": 63.23391072785357, "Pustule ": 2.946345586943139, "Rash ": 2.3210499514289067, "Recurrent cancer ": 10.40935008333442, "Respiratory failure ": 2.934398323478125, "SARS-CoV-2 test negative ": 12.007149456124772, "Skin disorder ": 5.413889254239975, "Skin fissures ": 16.32960554174431, "Skin toxicity ": 7.827041959957261, "Skin ulcer ": 2.032602812468616, "Small cell lung cancer ": 21.49811021775693, "Stomatitis ": 5.472740746696174, "Taste disorder ": 3.310603632309159, "Thrombocytopenia ": 3.9547086574369006, "Torsade de pointes ": 2.3862463935662435, "Tumour marker increased ": 11.272312365499168}
\ No newline at end of file
+{"Anaphylactic reaction": 45.18902925887953, "Anaphylactic shock": 25.2329362032695, "Atrial fibrillation": 8.112249070660205, "Bradycardia": 22.046847964900927, "Bronchospasm": 39.75421879118719, "Cardiac arrest": 16.758361704744704, "Drug interaction": 9.928121370377337, "Hypotension": 6.915904718605427, "Neuromuscular block prolonged": 783.3574580078387, "Neuromuscular blockade": 1233.7163544188072, "Off label use": 2.786559025276401, "Recurrence of neuromuscular blockade": 1591.5272849619423, "Respiratory failure": 24.706460043659813, "Tachycardia": 4.160728933769897}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1036.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1036.json
index 02c4965a9d8..94eab0324ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1036.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1036.json
@@ -1 +1 @@
-{"Injection site pain ": 2.943991133840602}
\ No newline at end of file
+{"Acute hepatic failure": 16.54972415045368, "Clostridium difficile colitis": 13.851988879341262, "Decreased appetite": 2.062663679196262, "Diarrhoea": 2.794433340307961, "Disease progression": 13.34261564834975, "Drug interaction": 6.668701108923167, "Electrocardiogram QT prolonged": 16.8902170475667, "Epistaxis": 2.618178916718264, "Hair colour changes": 30.246649169899676, "Hypertension": 8.780199481446322, "Hypothyroidism": 18.01285600587825, "Leukopenia": 4.028418329041707, "Malignant neoplasm progression": 4.075736551178736, "Mucosal inflammation": 17.0382805141317, "Neoplasm progression": 6.036755141801905, "Nephrotic syndrome": 23.75094271928633, "Neutropenia": 4.956319524288265, "Osteonecrosis of jaw": 86.25154931662397, "Pain in jaw": 8.918078838186114, "Palmar-plantar erythrodysaesthesia syndrome": 21.856100254812542, "Periodontal disease": 259.7499988829635, "Posterior reversible encephalopathy syndrome": 22.447372708534235, "Proteinuria": 9.455354143398926, "Stomatitis": 4.320431895169893, "Thrombocytopenia": 5.871552950238839, "Thrombotic microangiopathy": 30.93138083052052}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1037.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1037.json
index 1bf28b09ea0..de2763941c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1037.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1037.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 114.07796883334296, "Abnormal faeces ": 3.903878360679762, "Abortion ": 3.115044874824876, "Abortion missed ": 5.87576722310144, "Acute hepatic failure ": 3.425741380328815, "Acute respiratory distress syndrome ": 6.679424789011901, "Aggression ": 3.032944017602504, "Agitation ": 5.3963347810506255, "Altered state of consciousness ": 9.507906163289748, "Anaphylactoid reaction ": 3.8301099961695777, "Angle closure glaucoma ": 2.790985482849434, "Apgar score low ": 6.689197087648888, "Autoimmune haemolytic anaemia ": 2.522531017769136, "Blister rupture ": 10.521377997928758, "Blood creatine phosphokinase increased ": 3.2068567682790445, "Body temperature decreased ": 3.3078819957721097, "Brain death ": 4.459372039558303, "Cardiac failure acute ": 7.800588409694852, "Cardiac tamponade ": 2.7500536366681376, "Cardio-respiratory arrest ": 2.0566040796984324, "Chest X-ray abnormal ": 2.563153017956776, "Cholestasis ": 3.3356283298895386, "Chromaturia ": 5.318184432389533, "Colitis ischaemic ": 16.600111831222005, "Confusional state ": 2.8511448160267747, "Conjunctival hyperaemia ": 2.0502722129183675, "Conjunctivitis ": 2.129218440977306, "Conversion disorder ": 6.234781747084353, "Creatinine renal clearance decreased ": 2.254653211398667, "Crying ": 2.54104799896878, "Dehydration ": 2.0591875460345057, "Delirium ": 17.935615857079814, "Delirium febrile ": 48.52835963855505, "Delusion ": 14.63523803697848, "Depressed level of consciousness ": 2.425376970611416, "Dermatitis allergic ": 2.201679330322688, "Dermatitis bullous ": 2.2472244374861376, "Diarrhoea haemorrhagic ": 3.9338235951842746, "Disorientation ": 3.3320223622380887, "Disseminated intravascular coagulation ": 3.397094585647697, "Drug eruption ": 6.608636102100278, "Drug-induced liver injury ": 2.847283649830094, "Duodenal ulcer ": 2.650652489980656, "Duodenal ulcer haemorrhage ": 3.357202942013878, "Encephalitis ": 4.245496048573253, "Encephalopathy ": 5.498466830890743, "Enterocolitis haemorrhagic ": 85.3151506856073, "Erythema multiforme ": 8.721989369917017, "Erythema nodosum ": 2.1780017781447123, "Eye movement disorder ": 2.1886468204294136, "Faeces discoloured ": 2.5203141312227006, "Fear ": 4.375754331430009, "Foetal death ": 5.341308159496689, "H1N1 influenza ": 108.54891770019869, "Haematemesis ": 3.663986805918873, "Haematuria ": 2.1216630045715763, "Hallucination ": 20.317079053973675, "Hallucination, auditory ": 11.95068004286625, "Hallucination, visual ": 6.762625765982687, "Hallucinations, mixed ": 7.224798356858723, "Henoch-Schonlein purpura ": 4.087286149918017, "Hepatic cytolysis ": 4.7576935499245865, "Hepatic failure ": 2.8418831689433293, "Hepatic function abnormal ": 7.081140197926548, "Hepatitis ": 4.316767633661138, "Hepatitis A ": 12.622450927110243, "Hepatitis acute ": 5.5508965781441, "Hepatitis cholestatic ": 2.060264767255891, "Hepatitis fulminant ": 18.87629302680123, "Hypothermia ": 13.519531127114258, "Hypoxia ": 2.0473521077900894, "Illusion ": 4.0243510242320815, "Incoherent ": 4.829033897068582, "Influenza ": 2.643209913670965, "Influenza A virus test positive ": 49.66379759870595, "International normalised ratio increased ": 5.235228137226186, "Jaundice ": 2.6097438912683906, "Leukopenia ": 2.1455858788713704, "Liver disorder ": 5.3958315552922365, "Liver function test abnormal ": 3.129344253175592, "Loss of consciousness ": 3.35523421962547, "Lower limb fracture ": 2.0152148927423266, "Melaena ": 3.950543936748369, "Meningitis ": 2.1985142309196237, "Mental disorder ": 4.953582762655146, "Multiple organ dysfunction syndrome ": 3.639019186038419, "Neurological symptom ": 2.036530638883425, "Nightmare ": 8.08041709435329, "No adverse event ": 11.22079228665147, "Painful respiration ": 2.9870078531201028, "Panic attack ": 2.862934426803805, "Panic reaction ": 3.8643770514106337, "Paranoia ": 2.5087993514651235, "Pathogen resistance ": 17.821919168165415, "Periorbital swelling ": 2.1614824500275764, "Personality change ": 2.408148543568479, "Pneumonia ": 3.274296567186476, "Pneumonia bacterial ": 6.48537805099744, "Pneumonia influenzal ": 109.02266483115554, "Pneumonia viral ": 4.256901990761142, "Pregnancy ": 4.257014348911788, "Premature rupture of membranes ": 4.02042901331533, "Proteinuria ": 4.573017070850496, "Prothrombin time ratio increased ": 31.368353476497735, "Prothrombin time shortened ": 6.6192310343218805, "Psychiatric symptom ": 7.817796259819365, "Psychomotor hyperactivity ": 2.567700717582952, "Psychotic disorder ": 3.7222431832637297, "Rash morbilliform ": 3.810495463954853, "Respiratory failure ": 2.8999183535467306, "Restlessness ": 3.1186924182615128, "Rhabdomyolysis ": 3.450854041752684, "Screaming ": 6.345873868592912, "Seizure ": 4.228545496225292, "Self-destructive behaviour ": 4.547461525569352, "Sepsis ": 2.208975105164632, "Septic shock ": 2.096432832703791, "Shock ": 4.262421730175169, "Skin erosion ": 3.457178596653861, "Skin 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\ No newline at end of file
+{"Agitation": 3.851180370650725, "Depression": 4.237372718495712, "Drug interaction": 3.341036344521052, "Foetal exposure during pregnancy": 3.8997189349624337, "Gamma-glutamyltransferase increased": 14.588066774648752, "General physical health deterioration": 3.373776232891266, "Hallucination": 4.280479504365571, "Hepatic steatosis": 13.683564925922584, "Hepatitis": 8.30024654642637, "Lactic acidosis": 10.085088378464995, "Nightmare": 8.542291872123538, "Pancreatitis": 3.2123651582107637, "Pancreatitis acute": 12.270590573638067, "Rash maculo-papular": 7.275481477147968, "Suicidal ideation": 5.695086941939819}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1038.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1038.json
index 162e0bbe9e4..7e02f1fc9c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1038.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1038.json
@@ -1 +1 @@
-{"Acute kidney injury ": 4.482919413466625, "Dermatitis acneiform ": 109.56520027175364, "Diarrhoea ": 3.910977844504598, "Drug interaction ": 8.112214270459697, "International normalised ratio increased ": 8.283980724673425, "Interstitial lung disease ": 9.02994101022334, "Rash ": 3.1257014022538145}
\ No newline at end of file
+{"Abdominal abscess": 2.3391581175465386, "Abdominal infection": 3.762050249305125, "Acute cholecystitis necrotic": 7.1105715673798695, "Ageusia": 7.004153537337828, "Alveolar soft part sarcoma": 15.921463651607532, "Anaemia": 2.398254420202442, "Anal abscess": 4.059616054555711, "Anal fissure": 4.543616104988348, "Anal fistula": 4.898771255917191, "Anal haemorrhage": 8.008286932459692, "Anal inflammation": 10.162914772680605, "Anal injury": 36.236474889033325, "Anal ulcer": 8.107322616792056, "Angular cheilitis": 4.023956704497161, "Anorectal discomfort": 4.30887643639417, "Anorectal disorder": 5.018092754543758, "Aortic dissection": 3.9955341771317134, "Aphthous ulcer": 5.682649876807576, "Appetite disorder": 2.685414356921994, "Ascites": 4.017895439174292, "Asthenia": 2.1726027204896616, "Blister": 3.321974955728798, "Blister infected": 6.372662650728437, "Blood albumin decreased": 2.6279206576215093, "Blood bilirubin abnormal": 3.5386493462540227, "Blood blister": 3.500253335141063, "Blood calcium abnormal": 2.57757354844122, "Blood calcium increased": 2.3028050684551964, "Blood creatine increased": 2.7522577917004902, "Blood creatinine abnormal": 3.4523187163552587, "Blood creatinine increased": 2.315285807699235, "Blood disorder": 3.284443840798655, "Blood magnesium decreased": 3.281013450172523, "Blood pressure abnormal": 2.329957169445774, "Blood pressure fluctuation": 2.02124417501229, "Blood pressure increased": 3.849954427133298, "Blood sodium decreased": 3.658482291174934, "Blood sodium increased": 2.228465916762358, "Blood test abnormal": 2.341882650308621, "Blood thyroid stimulating hormone abnormal": 5.230389051020488, "Blood thyroid stimulating hormone decreased": 2.0194300089519306, "Blood thyroid stimulating hormone increased": 14.965355726989705, "Blood triglycerides abnormal": 3.5954675891548744, "Blood urea increased": 2.2121166612252656, "Blood uric acid increased": 2.141007434981585, "Blood urine": 7.691496680003189, "Blood urine present": 4.383643330079826, "Bone lesion": 2.5302822710511506, "Burn oesophageal": 2.167730588378632, "Burn oral cavity": 6.895188913261053, "Cachexia": 2.438230656936253, "Cancer pain": 8.96126384258416, "Carcinoid tumour": 3.3841956467457885, "Cardiac failure": 2.4892882041686946, "Cardiopulmonary failure": 24.860420355800468, "Cardiotoxicity": 2.1791008956185025, "Central hypothyroidism": 2.739832016658553, "Chapped lips": 5.867529615773645, "Cholecystitis": 3.4510964881742425, "Cholecystitis infective": 5.337647260819533, "Chromaturia": 3.326086694609291, "Clear cell renal cell carcinoma": 9.14076398062605, "Colonic fistula": 7.961280334690032, "Coma hepatic": 2.4195931960653936, "Constipation": 2.5282163737045016, "Death": 5.635915406408736, "Decreased appetite": 4.0084959081960765, "Decreased immune responsiveness": 7.924656135948564, "Decubitus ulcer": 6.584648758911328, "Dehydration": 3.133236646831104, "Diarrhoea": 2.66871649566791, "Disease progression": 32.37047811634612, "Disseminated intravascular coagulation": 2.1243016498100364, "Diverticular perforation": 2.418723208928036, "Dry mouth": 2.302834908932743, "Dry skin": 9.181271766145445, "Duodenal perforation": 2.306369514102645, "Dyschezia": 3.758019712574744, "Dysentery": 5.161163082067929, "Dysgeusia": 3.346460672559044, "Dyspepsia": 3.971429391513728, "Eating disorder": 8.328880800552078, "Ejection fraction decreased": 4.431792451805119, "Epistaxis": 3.75529879419692, "Eructation": 2.502658975755995, "Exposed bone in jaw": 18.61562798206001, "Eye colour change": 5.289142103421447, "Eye swelling": 2.5023148809084, "Eyelash discolouration": 44.67334519262169, "Eyelid oedema": 2.0434233132144115, "Eyelid pain": 2.306369514102645, "Faeces discoloured": 2.147041510627341, "Faeces soft": 2.4753697147265905, "Feeding disorder": 6.76616756268536, "Fistula": 3.503006845329977, "Fistula of small intestine": 9.323279106639555, "Flatulence": 4.165876258667662, "Fluid intake reduced": 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recession": 3.608593798958621, "Gingival swelling": 6.428086433308337, "Gingivitis": 2.1932608461011385, "Glossitis": 5.439892588161064, "Glossodynia": 3.8732505966282864, "Gout": 2.2146413621083147, "Haematemesis": 3.158116476345672, "Haematochezia": 2.688474710731836, "Haematotoxicity": 2.266795220152406, "Haematuria": 2.047454739302634, "Haemoglobin decreased": 2.490257189396317, "Haemoptysis": 3.329985580096804, "Haemorrhage": 2.8839882624162136, "Haemorrhage urinary tract": 4.062910248861032, "Haemorrhagic diathesis": 2.254501992976191, "Haemorrhoidal haemorrhage": 6.045258780466201, "Haemorrhoids": 3.584597450537875, "Hair colour changes": 40.61344201843543, "Hair disorder": 2.4480651699949654, "Hair texture abnormal": 2.6621926292561016, "Hand-foot-and-mouth disease": 5.538883253152427, "Hepatic infection": 3.9360510525814494, "Hepatorenal failure": 2.509068768949616, "Hernia": 2.339949888328551, "Hiccups": 5.597375106076228, "Hydrothorax": 7.526402980153036, "Hyperaesthesia": 2.6614116739016898, "Hyperaesthesia teeth": 2.502382853143841, "Hyperchlorhydria": 16.613239145022153, "Hypercreatininaemia": 2.93812170040978, "Hyperkeratosis": 19.39457401821049, "Hypertension": 4.11077621459278, "Hyperthyroidism": 2.77201306962794, "Hypoalbuminaemia": 2.4568667420381054, "Hypogeusia": 11.05138683276546, "Hypophagia": 4.352298907860018, "Hypothyroidism": 8.881013048743606, "Impaired healing": 2.7867021470032425, "Incision site pain": 5.733520818341887, "Ingrowing nail": 3.7793926545348615, "Inguinal hernia": 2.2975392509032786, "Internal haemorrhage": 2.577645981282433, "Intestinal fistula": 5.005842009498007, "Intestinal haemorrhage": 2.587177589311766, "Intestinal obstruction": 2.119258543409182, "Intestinal perforation": 4.532238415176344, "Jaundice": 2.2535487781117944, "Jaw disorder": 4.672011813112553, "Lacrimal disorder": 6.918179913949738, "Lacrimation increased": 2.3554626539753007, "Large intestine perforation": 2.8046291593743256, "Leukoencephalopathy": 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"Nail disorder": 2.415296057715313, "Nasal discomfort": 2.9588662733784177, "Nasal disorder": 4.63329954044934, "Nasal dryness": 4.625293227926113, "Nasal injury": 5.5639954846559565, "Nasal septum perforation": 3.333085646932914, "Neoplasm malignant": 2.3728855243674007, "Neoplasm progression": 34.323537058531734, "Neoplasm recurrence": 4.9972679489896725, "Nephrectomy": 2.8421971137719275, "Nephrotic syndrome": 8.49909098633634, "Nodule": 2.0425792440298944, "Noninfective gingivitis": 4.421186071343388, "Nutritional condition abnormal": 3.580632308906661, "Ocular vascular disorder": 2.7693538044493304, "Oesophageal haemorrhage": 3.692715503383607, "Oesophageal ulcer": 4.264049856619808, "Oesophagitis": 2.1063157799817405, "Oesophagitis ulcerative": 3.763101482157203, "Onychalgia": 5.005842009498007, "Onychoclasis": 2.276708699151885, "Onycholysis": 2.3181135166316458, "Oral discomfort": 6.408646533876267, "Oral disorder": 5.316941268189884, "Oral infection": 2.229445226914221, "Oral mucosal blistering": 8.636912442747827, "Oral mucosal erythema": 4.039529773797027, "Oral mucosal exfoliation": 4.4912474570983525, "Oral pain": 19.96951294766144, "Orbital oedema": 4.658957808793553, "Organ failure": 8.207036630176999, "Oropharyngeal plaque": 3.277121182050417, "Osteonecrosis of jaw": 12.096488930299095, "Palmar erythema": 4.191795325553512, "Palmar-plantar erythrodysaesthesia syndrome": 24.47628641913144, "Pancreatic neuroendocrine tumour": 20.864515423654787, "Pancreatic neuroendocrine tumour metastatic": 12.17630317638663, "Pathological fracture": 2.895754832619012, "Penile exfoliation": 12.01035007198319, "Penile haemorrhage": 3.41170810043502, "Pericardial effusion": 2.1272215150446274, "Perineal pain": 4.01092266521451, "Periorbital oedema": 4.99531649598575, "Peritonitis": 2.1670159327057403, "Phaeochromocytoma": 2.604442496067667, "Pharyngeal inflammation": 2.2866218367043203, "Pharyngeal ulceration": 3.232553209977329, "Pigmentation disorder": 2.337015348270204, "Plantar erythema": 14.826463525322955, "Platelet count decreased": 7.032045747786856, "Platelet disorder": 2.5320072227222896, "Pleural effusion": 3.7635509472987874, "Pneumatosis intestinalis": 2.083110608442775, "Posterior reversible encephalopathy syndrome": 2.1504805957322097, "Primary hypothyroidism": 5.187849881936481, "Proctalgia": 6.404032749282061, "Prostatomegaly": 2.1532617621033867, "Protein total decreased": 3.1244395552488444, "Protein urine present": 3.3680442571527114, "Proteinuria": 2.802689389608265, "Pulmonary oedema": 2.313770840339474, "Purulence": 2.7821604541876006, "Pyoderma gangrenosum": 5.948685801636843, "Rectal abscess": 2.9271107066077224, "Rectal ulcer": 3.145071589462309, "Red blood cell abnormality": 2.321015019291003, "Red blood cell count decreased": 3.086688881851058, "Reflux gastritis": 7.967462976393679, "Renal cancer": 8.196200363992443, "Renal cancer metastatic": 99.11193749236809, "Renal cancer stage IV": 61.73362945749711, "Renal cell carcinoma": 136.52478622060704, "Renal cell carcinoma stage IV": 33.897925219235326, "Renal disorder": 2.2651712112376727, "Renal haemorrhage": 4.499013754315997, "Renal impairment": 2.371764479559809, "Renal vein thrombosis": 3.407507734319413, "Retching": 2.907189859546843, "Scrotal erythema": 9.508684115981488, "Second primary malignancy": 18.214793728660045, "Single functional kidney": 4.721462187528247, "Skin abrasion": 2.7391292905527265, "Skin atrophy": 6.306586957481456, "Skin depigmentation": 4.164817107550587, "Skin discolouration": 5.656503771902612, "Skin disorder": 2.8129200341919827, "Skin exfoliation": 6.499159210154603, "Skin fissures": 15.581945224212548, "Skin haemorrhage": 3.2615613082870403, "Skin hypertrophy": 3.940237016269292, "Skin injury": 2.56417364934112, "Skin irritation": 2.929851122523308, "Skin lesion": 3.363434436544172, "Skin papilloma": 3.456149548513844, "Skin sensitisation": 9.766567901227674, "Skin toxicity": 5.448366793062228, "Skin ulcer": 3.5386272463357527, "Skin wound": 3.636360983623124, "Sluggishness": 2.243010609074584, "Small intestinal perforation": 2.028037825982242, "Spinal disorder": 2.2657431380422253, "Stomatitis": 10.170077941736729, "Sweat discolouration": 8.89144158847802, "Taste disorder": 13.1972229528317, "Temperature intolerance": 2.480135351840312, "Testicular disorder": 2.0326820526824707, "Testicular swelling": 2.178683498105063, "Throat lesion": 12.908766415428609, "Thrombocytopenia": 3.392687528618625, "Thrombotic microangiopathy": 2.288192137363575, "Thrombotic thrombocytopenic purpura": 2.1411978385745587, "Thyroid disorder": 9.350701788490214, "Thyroid function test abnormal": 10.948351156676772, "Thyroid hormones increased": 3.547523108168235, "Thyroxine decreased": 5.488841188910136, "Tongue blistering": 6.136298379241493, "Tongue discomfort": 7.150829389691351, "Tongue disorder": 6.277673621277647, "Tongue dry": 4.057836595398968, "Tongue erythema": 6.330261428804369, "Tongue exfoliation": 6.761081729828359, "Tongue injury": 11.859503207379664, "Tongue rough": 5.148860036055853, "Tongue ulceration": 2.403934796334707, "Tooth abscess": 2.9434452501318784, "Tooth disorder": 4.390206126690364, "Tooth infection": 3.2699464077322715, "Toothache": 2.2566491094795267, "Trichorrhexis": 2.188502203420137, "Tumour haemorrhage": 17.85792949201236, "Tumour lysis syndrome": 3.595700422899239, "Tumour necrosis": 4.978336043355714, "Tumour pain": 23.99259038738648, "Tumour rupture": 26.250276919291267, "Urethral obstruction": 8.150757755093785, "Urinary bladder haemorrhage": 2.4394362170736423, "Urinary tract disorder": 2.0129103327392257, "Vena cava thrombosis": 6.374150088928209, "Walking disability": 2.178228094310436, "Weight decreased": 3.1903766714356707, "Weight fluctuation": 5.697166341222836, "White blood cell count decreased": 2.9913862895759507, "Wound": 2.438657392517346, "Wound complication": 4.901226216271909, "Wound dehiscence": 4.327082968466441, "Wound haemorrhage": 2.595067978966173, "Wound infection": 2.8503196032162275, "Yellow skin": 81.6430776976172}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1039.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1039.json
index bd5cec427fc..16a635670e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1039.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1039.json
@@ -1 +1 @@
-{"Abdominal tenderness ": 2.386699136694868, "Acute coronary syndrome ": 5.4828793947312695, "Acute lymphocytic leukaemia ": 7.485428183983045, "Acute myocardial infarction ": 6.659416816532057, "Alanine aminotransferase increased ": 3.008248203361484, "Amylase increased ": 17.283809620785814, "Anaemia ": 2.037020907871262, "Angina pectoris ": 6.4167786430618, "Angina unstable ": 5.935670670071813, "Angiopathy ": 8.542773693010151, "Anxiety ": 3.017489100464697, "Aortic aneurysm ": 2.6651883678180024, "Aortic arteriosclerosis ": 11.145538448411177, "Aortic stenosis ": 4.972108266025858, "Aplastic anaemia ": 2.09445202044265, "Arterial disorder ": 42.12464685714461, "Arterial occlusive disease ": 13.056470869488132, "Arterial stenosis ": 28.642650355179452, "Arterial thrombosis ": 5.013581101586812, "Arteriosclerosis ": 80.4653115628525, "Arteriosclerosis coronary artery ": 6.380077641824245, "Arteriospasm coronary ": 3.099875018838641, "Arteritis ": 16.57097312249361, "Aspartate aminotransferase increased ": 2.5276394109229448, "Atelectasis ": 2.1153497301608684, "Atrial fibrillation ": 3.4710419111827298, "Autoimmune thyroiditis ": 2.6203686052422857, "Benign prostatic hyperplasia ": 2.055103741290894, "Bilirubin conjugated increased ": 3.171598895672937, "Blast cell crisis ": 65.787395033958, "Blast crisis in myelogenous leukaemia ": 277.4737966803825, "Blood bilirubin increased ": 12.354251044771951, "Blood bilirubin unconjugated increased ": 16.73196857723267, "Bone marrow failure ": 8.899644590604984, "Bone pain ": 2.1865317160232878, "Brain natriuretic peptide increased ": 3.123549213064432, "Cardiac failure ": 2.7953130264371016, "Cardiac tamponade ": 4.113809368678278, "Cardiomegaly ": 2.980649541307642, "Carotid arteriosclerosis ": 34.89484449192835, "Carotid artery disease ": 12.284041145271209, "Carotid artery occlusion ": 12.77430639400956, "Carotid artery stenosis ": 73.38479983987187, "Cerebral artery occlusion ": 11.71336612691688, "Cerebral artery stenosis ": 77.25596773348751, "Cerebral infarction ": 8.42071961479401, "Cerebrovascular accident ": 3.744346334720356, "Cholecystitis acute ": 2.670496382121365, "Chronic myeloid leukaemia ": 172.46878921990853, "Chronic myeloid leukaemia recurrent ": 87.34681272528503, "Chronic myeloid leukaemia transformation ": 260.0588765360084, "Complex regional pain syndrome ": 5.617520289588552, "Concomitant disease aggravated ": 9.48085887258679, "Concomitant disease progression ": 13.895689962762471, "Coronary artery disease ": 11.219695878800598, "Coronary artery occlusion ": 10.821124267484125, "Coronary artery stenosis ": 15.07416756865447, "Cytogenetic analysis abnormal ": 104.52596741157228, "Cytopenia ": 7.478090340930419, "Death ": 2.1819640638041244, "Diabetes mellitus ": 5.095826424126925, "Diastolic dysfunction ": 4.368524650715163, "Drug resistance ": 2.747641535817559, "Dry skin ": 3.0863657914500533, "Dyslalia ": 6.119056515059161, "Dyslipidaemia ": 6.6961612187379895, "Electrocardiogram QT prolonged ": 12.345776215008677, "Emotional distress ": 7.998916420866814, "Essential hypertension ": 7.444960695895315, "Fluid retention ": 2.621310339943341, "Full blood count decreased ": 4.369976028996687, "Gamma-glutamyltransferase increased ": 2.2082758285107484, "Gangrene ": 13.01727473089618, "Gastrointestinal stromal tumour ": 5.131715129071721, "Gene mutation identification test positive ": 96.46885624299524, "Glucose tolerance impaired ": 3.8883943644847903, "Goitre ": 2.552399816687647, "Haematocrit decreased ": 2.5115994343114387, "Haematotoxicity ": 5.449363736664067, "Haemoglobin decreased ": 2.3349230606016635, "Hemiplegia ": 3.5214186186086374, "Hepatotoxicity ": 4.890901328588043, "Hyperbilirubinaemia ": 7.654302023865514, "Hypercholesterolaemia ": 9.74211879235081, "Hyperlipidaemia ": 7.029087789173481, "Hypertriglyceridaemia ": 2.075230482735936, "Infarction ": 5.2910010868976745, "Injury ": 20.58623093858763, "Intermittent claudication ": 138.1047019969824, "Intervertebral disc degeneration ": 2.514240863974114, "Intervertebral disc protrusion ": 2.0117182731620606, "Iron deficiency anaemia ": 3.205769918998977, "Ischaemia ": 7.443940733897348, "Ischaemic cardiomyopathy ": 4.209436227066488, "Ischaemic stroke ": 4.655592818252318, "Jaundice ": 2.3496068836225987, "Lactose intolerance ": 6.416781284253575, "Left ventricular dysfunction ": 2.668084826914534, "Left ventricular hypertrophy ": 6.120326506146673, "Leukaemia ": 2.1325683615721696, "Leukaemia recurrent ": 16.504493091168484, "Leukocytosis ": 4.133510356755458, "Lipase increased ": 32.00851409859394, "Liver disorder ": 2.637982610648082, "Liver function test increased ": 2.099874599126551, "Malignant neoplasm progression ": 4.4327934507756375, "Mitral valve incompetence ": 6.256271534798794, "Myelodysplastic syndrome ": 2.2255842714048435, "Myocardial infarction ": 4.50384630647375, "Myocardial ischaemia ": 8.118521790355238, "Nasal oedema ": 5.413016265413506, "Necrosis ": 5.092873782852443, "Oncologic complication ": 42.08369048026828, "Pancreatic enzymes increased ": 8.129112609753763, "Pancreatitis ": 8.25315426615855, "Pancreatitis acute ": 4.089603474774221, "Pancytopenia ": 6.349180443577289, "Papilloedema ": 2.919851787487163, "Paternal exposure during pregnancy ": 15.186235814275127, "Pericardial effusion ": 8.404129158562077, "Periorbital oedema ": 2.576622043072833, "Peripheral arterial occlusive disease ": 239.31663393931655, "Peripheral artery occlusion ": 55.40814471022747, "Peripheral artery stenosis ": 186.3985226001778, "Peripheral artery thrombosis ": 10.042240319792011, "Peripheral ischaemia ": 10.61232327409314, "Peripheral vascular disorder ": 25.99487833468264, "Philadelphia chromosome positive ": 41.05154737863561, "Platelet count decreased ": 4.234158264557448, "Platelet count increased ": 4.554988105601887, "Pleural effusion ": 7.861704993037496, "Pleurisy ": 2.5530031025859348, "Pulmonary hypertension ": 2.275815826709607, "Pulmonary oedema ": 2.149676524855153, "Renal artery stenosis ": 9.94674632921896, "Second primary malignancy ": 36.74854294651669, "Sensory loss ": 2.206685171643554, "Skin ulcer ": 2.8546315394564266, "Splenomegaly ": 4.732481892346645, "Stenosis ": 11.210949488634633, "Supraventricular extrasystoles ": 5.321136103174236, "Therapeutic response decreased ": 2.204898237344297, "Therapy non-responder ": 2.4665283458895737, "Thrombocytopenia ": 3.955956227145375, "Thrombocytosis ": 8.865542933185997, "Transaminases increased ": 2.4058786328694723, "Transient ischaemic attack ": 4.39126712203474, "Tricuspid valve incompetence ": 8.219420076582026, "Type 2 diabetes mellitus ": 2.289257638937851, "Ulcer ": 2.170221532082966, "Vascular occlusion ": 7.11349297118067, "Vascular stenosis ": 38.024486356969085, "Ventricular extrasystoles ": 2.034533105756093, "Vertebral artery stenosis ": 93.88610492639148, "White blood cell count increased ": 7.075524074978095}
\ No newline at end of file
+{"Adverse event": 6.207632202515212, "Agitation": 3.840086729726572, "Akathisia": 54.24927311229766, "Blood creatine phosphokinase increased": 4.372535158103086, "Bradykinesia": 44.57062450084656, "Delirium": 2.5435506695251493, "Disease recurrence": 4.334377342903216, "Disorientation": 6.522114262989159, "Drug-induced liver injury": 3.6339299462008894, "Dysarthria": 11.53932727711263, "Dysgeusia": 10.523392391982188, "Dyskinesia": 9.832642160628982, "Dysphagia": 3.72985930246459, "Dystonia": 11.28204736198916, "Electrocardiogram QT prolonged": 2.6684345088925614, "Extrapyramidal disorder": 65.71557977440469, "Generalised tonic-clonic seizure": 6.330328912397482, "Hospitalisation": 3.449759212018085, "Hypoaesthesia oral": 22.59341818626025, "Incorrect route of product administration": 23.306713323462887, "Increased appetite": 13.876496757354449, "Insomnia": 2.409123188764614, "Mania": 13.290526507603497, "Muscle rigidity": 13.567981271452318, "Muscle twitching": 3.480614704247663, "Nervousness": 2.9747076280888964, "Neuroleptic malignant syndrome": 59.92183755876987, "Off label use": 4.292096180564177, "Oral dysaesthesia": 163.14584172802412, "Paraesthesia oral": 5.346089278198875, "Parkinsonism": 42.65624719921861, "Pneumonia aspiration": 12.841027614980089, "Polydipsia": 25.35471915052848, "Prescribed overdose": 9.10113487826083, "Product taste abnormal": 23.7928495376452, "Psychomotor hyperactivity": 13.138707361169436, "Restless legs syndrome": 12.21988547548867, "Restlessness": 6.105658585660609, "Rhabdomyolysis": 7.34031382418971, "Salivary hypersecretion": 9.413352006965628, "Schizophrenia": 50.00330337169883, "Sedation": 38.9396529498552, "Sedation complication": 44.55508030635309, "Somnolence": 3.420558008435357, "Sopor": 12.741456486049302, "Suicidal ideation": 3.0313231557855578, "Suicide attempt": 5.416595422515599, "Tongue oedema": 10.430493009811324, "Tooth discolouration": 24.008684659261984, "Treatment noncompliance": 3.565968694159596, "Underdose": 4.4439306238259295, "Urinary incontinence": 9.408509834622276, "Urinary retention": 5.11871772005341, "Water intoxication": 158.27905800056652, "Weight increased": 2.8009153058188665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/104.json
index b492089504e..ae10e1acfe3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/104.json
@@ -1 +1 @@
-{"Alanine aminotransferase abnormal ": 110.52070008424252, "Alanine aminotransferase increased ": 3.219699621697369, "Anal atresia ": 952.249070345796, "Anencephaly ": 784.0312787137402, "Aspartate aminotransferase abnormal ": 209.5312950032599, "Bladder agenesis ": 39404.1228813144, "Blood alkaline phosphatase increased ": 10.626364852276328, "Blood bilirubin increased ": 17.35154857583515, "Blood iron decreased ": 123.41799091410346, "Caudal regression syndrome ": 2636.088350718861, "Cholelithiasis ": 41.75148063711991, "Cloacal exstrophy ": 17988.291258625384, "Congenital anomaly ": 65.95198645740592, "Congenital ectopic bladder ": 5543.213819601852, "Congenital genital malformation ": 1569.8309245199737, "Congenital musculoskeletal disorder ": 547.0517563409115, "Congenital musculoskeletal disorder of spine ": 1140.4637512091592, "Drug-induced liver injury ": 6.756674975295933, "Erythema ": 2.762581063571254, "Exomphalos ": 901.5852294731764, "Exposure during pregnancy ": 5.743266026759097, "Fibrosis ": 124.22201749932825, "Foetal exposure during pregnancy ": 5.654519907981118, "Gastrointestinal disorder congenital ": 4701.065232172242, "Gastrointestinal malformation ": 1714.2496582015333, "Genitalia external ambiguous ": 3472.013490665753, "Hepatic cytolysis ": 10.8942409411567, "Hepatic enzyme increased ": 7.6700180362842625, "Hepatotoxicity ": 12.607378882023747, "Hypomania ": 58.1016134272866, "Jaundice ": 19.5686164861567, "Jaundice cholestatic ": 51.086931422449055, "Lipodystrophy acquired ": 313.1885069513086, "Pneumonia ": 3.698393232766496, "Premature labour ": 50.64353106010293, "Product use in unapproved indication ": 2.6650335679573085, "Psychotic disorder ": 9.227838194335083, "Schizophrenia ": 116.30765672503898, "Tinnitus ": 3.683780988840986, "Vomiting ": 2.333558757706116}
\ No newline at end of file
+{"Abdominal discomfort": 3.432034511827625, "Abdominal distension": 3.0218247559599405, "Adjustment disorder with depressed mood": 113.06969794229198, "Adverse drug reaction": 21.84387452660102, "Adverse reaction": 12.46491837827897, "Alanine aminotransferase increased": 2.3560331402429986, "Alopecia": 4.916715467900437, "Amnesia": 11.50680238375522, "Anti-cyclic citrullinated peptide antibody positive": 33.096166370714364, "Arthropathy": 12.876044526087918, "Aspartate aminotransferase increased": 2.6935852788759296, "Autoimmune disorder": 17.645462022278814, "Back injury": 18.11018938569901, "Basal cell carcinoma": 21.484128842708625, "Blepharospasm": 59.4378117934347, "Blood cholesterol increased": 21.31229026981577, "Blood parathyroid hormone decreased": 77.84293364138503, "Breast cancer stage III": 18.235486175493147, "Bursitis": 16.22235912199517, "C-reactive protein": 58.05933439558506, "C-reactive protein abnormal": 21.789986044552595, "C-reactive protein increased": 13.370135687516507, "Coeliac disease": 15.557613018461916, "Condition aggravated": 2.8278864145491256, "Confusional state": 2.6737909583585724, "Contraindicated product administered": 15.695889562123552, "Cytokine storm": 66.60349547674689, "Decreased appetite": 2.591952328181304, "Deep vein thrombosis postoperative": 8.384900697958118, "Delirium": 15.28440478114908, "Disability": 3.594502714886528, "Discomfort": 9.890262784334508, "Dislocation of vertebra": 221.507324583466, "Disseminated intravascular coagulation": 3.682433240215802, "Drug eruption": 5.853536931596886, "Drug hypersensitivity": 11.75709119040272, "Drug intolerance": 5.091118304412586, "Drug tolerance decreased": 27.00138262471977, "Drug-induced liver injury": 4.863026543824333, "Dry mouth": 3.4830221569089703, "Duodenal ulcer perforation": 23.935253822625956, "Dyspepsia": 3.7391949386541614, "Enthesopathy": 96.69622785994478, "Epilepsy": 10.010226227238338, "Facet joint syndrome": 44.73696129518514, "Fibromyalgia": 12.549137230118596, "Finger deformity": 24.512138915914203, "Folliculitis": 13.266354768790489, "Gait disturbance": 4.878890505871176, "Gait inability": 7.760141213654442, "Gastrointestinal disorder": 3.0132122026620216, "Gastrooesophageal reflux disease": 6.037412219410965, "General physical health deterioration": 5.652607483802892, "Glossodynia": 5.044314927048245, "Granuloma skin": 113.51445573635232, "Grip strength decreased": 93.42765945488998, "Hand deformity": 13.597033352859649, "Helicobacter infection": 14.214965474978568, "Hepatic enzyme increased": 6.670186334260973, "Hip arthroplasty": 19.70174355969116, "Hypercalcaemia": 16.766447692907377, "Hypercholesterolaemia": 3.1427390531804567, "Hypersensitivity": 3.161166247713074, "Hypoaesthesia": 3.4200725946268364, "Incorrect route of product administration": 4.563710557295238, "Inflammation": 6.197968463667811, "Infusion related reaction": 13.742923219633482, "Injury": 10.42637180714462, "Iron deficiency": 16.683504571789697, "Joint swelling": 5.527664314302268, "Knee arthroplasty": 18.174431140073462, "Lip dry": 7.089402273940031, "Live birth": 28.497321730821493, "Liver injury": 5.634168981451155, "Loss of personal independence in daily activities": 2.978394408819015, "Lower limb fracture": 16.03664259157772, "Maternal exposure during pregnancy": 2.6306432381254594, "Memory impairment": 3.471302949247177, "Migraine": 2.620634789629685, "Mobility decreased": 12.221507413573692, "Muscle injury": 21.68880441626898, "Muscular weakness": 3.1031281553987, "Musculoskeletal pain": 9.06383803522002, "Musculoskeletal stiffness": 10.823090623686443, "Night sweats": 2.2905177900150364, "Obesity": 6.346264408954157, "Osteoarthritis": 2.873053991334549, "Panniculitis": 53.17751302090653, "Pemphigus": 2.069948935221054, "Pericarditis": 5.153502246351762, "Peripheral swelling": 3.2941311668734694, "Peripheral venous disease": 21.312116555646824, "Prescribed overdose": 3.014320009463184, "Product quality issue": 10.715493763558364, "Product use in unapproved indication": 2.8384190819698927, "Product use issue": 2.3079170981950936, "Psoriatic arthropathy": 25.479445587990757, "Rash pruritic": 2.1632925714268985, "Red blood cell sedimentation rate": 447.2689026325131, "Red blood cell sedimentation rate abnormal": 5.828459560207387, "Red blood cell sedimentation rate increased": 6.650550715651783, "Retroperitoneal haematoma": 19.220423831318243, "Rheumatic fever": 156.28610650017237, "Rheumatoid arthritis": 7.7303399343699954, "Rheumatoid factor positive": 69.50122848091762, "Sciatica": 6.610966849558594, "Septic shock": 2.0968844127904083, "Shock haemorrhagic": 6.352401593648557, "Skin abrasion": 4.924091944392407, "Sleep disorder": 5.225999522163675, "Sleep disorder due to general medical condition, insomnia type": 11.305619946130903, "Swelling": 2.01257633174931, "Swollen joint count increased": 130.637047524376, "Synovitis": 4.9177431661289726, "Systemic lupus erythematosus": 2.329742859258386, "Taste disorder": 7.716361181389326, "Therapeutic product effect decreased": 10.591935002520287, "Treatment failure": 6.552691013964545, "Weight decreased": 2.161337933005101, "Wound": 2.428650396518941}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1040.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1040.json
index f9dff1e1bb3..a8f0d217615 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1040.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1040.json
@@ -1 +1 @@
-{"Confusional state ": 5.669563911778029, "Dyskinesia ": 28.03310513943156}
\ No newline at end of file
+{"Disease progression": 17.14924489097697, "Infusion related reaction": 10.35582239423618, "Neutropenia": 3.97892145707637, "Off label use": 6.3657720319622015, "Pneumonia": 2.8100841058076487, "Thrombocytopenia": 4.540810287748204}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1041.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1041.json
index 8a380b6bde5..90e7155fb2a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1041.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1041.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 24.392855630902638, "Agranulocytosis ": 32.64999280948443, "Alopecia ": 15.24131808896068, "Breast cancer ": 2.3841679570405825, "Cardiac failure ": 3.704832408648704, "Diarrhoea ": 2.6104785225720466, "Febrile bone marrow aplasia ": 47.19696517020128, "Febrile neutropenia ": 10.331509711212863, "Flushing ": 3.3897819379479044, "Granulocytopenia ": 10.188942004006318, "Hepatic function abnormal ": 2.8702610770476173, "Interstitial lung disease ": 8.553226188585219, "Leukopenia ": 15.417388750327724, "Lung disorder ": 2.001515387755858, "Malignant neoplasm progression ": 2.4246877508444062, "Mucosal inflammation ": 10.3136214171609, "Myelosuppression ": 17.546431551703954, "Neuropathy peripheral ": 2.272630804462859, "Neutropenia ": 8.59562045425204, "Neutrophil count decreased ": 13.76337197432074, "Oedema ": 3.1204572923275715, "Palmar-plantar erythrodysaesthesia syndrome ": 4.153081478533539, "Pancytopenia ": 3.252733923666057, "Pleural effusion ": 2.617807302711724, "Pneumonitis ": 3.392565185806798, "Prostatic specific antigen increased ": 8.12737713949123, "Psychological trauma ": 231.20972511778865, "Sepsis ": 2.791674046342254, "Septic shock ": 4.0061911267247465, "Skin exfoliation ": 4.51448753622689, "Stomatitis ": 9.298416330429918, "White blood cell count decreased ": 15.763995605032802}
\ No newline at end of file
+{"Blood HIV RNA increased": 181.838687104936, "Blood cholesterol increased": 5.4785669164247714, "Coronavirus infection": 52.27277024392599, "Dyslipidaemia": 89.77957649352986, "Hypercholesterolaemia": 53.33628903283755, "Pruritus": 2.458761266839211, "Rash": 3.1162543163507226, "Self-destructive behaviour": 50.20958343048842, "Treatment noncompliance": 10.059402853288685, "Viral load increased": 104.16448448730864, "Weight increased": 4.092895577177306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1042.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1042.json
index a75cd539fa9..a7e851b01fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1042.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1042.json
@@ -1 +1 @@
-{"Balance disorder ": 5.827939587163809, "Fall ": 3.620270209584692, "Flushing ": 13.435949972517502, "Gait disturbance ": 3.117955456330314, "Gastrointestinal disorder ": 2.9706934730808774, "Memory impairment ": 6.514345875131827, "Multiple sclerosis ": 46.771396749336944, "Multiple sclerosis relapse ": 48.757346912509696, "Muscle spasms ": 3.784136065385861, "Muscle spasticity ": 27.698310389422748, "Muscular weakness ": 2.5932401840977333, "Urinary tract disorder ": 83.19803877622537}
\ No newline at end of file
+{"Acute respiratory distress syndrome": 2.907248433349792, "Acute respiratory failure": 6.42624382479321, "Adenovirus infection": 22.940543342728503, "Apnoea": 57.086794905206126, "Apnoeic attack": 53.88703751774717, "Asphyxia": 2.152085770439844, "Aspiration": 11.833684310483688, "Atelectasis": 9.246859874464857, "Atrial septal defect": 2.501706363876992, "Bacterial infection": 2.467701493472656, "Body temperature decreased": 2.173370207569456, "Bradycardia": 2.585727772024736, "Bronchial hyperreactivity": 16.734990816283222, "Bronchiolitis": 795.1510498098093, "Bronchitis": 11.508272671282564, "Bronchopulmonary dysplasia": 165.70738011159432, "Cardiac arrest": 2.315989397374406, "Cardiac disorder": 4.724349441298711, "Cardiac operation": 95.26774454518748, "Cardio-respiratory arrest": 2.4308459085667007, "Catheterisation cardiac": 7.862698151945158, "Cerebral palsy": 32.6368993802519, "Choking": 2.8745433807955103, "Chronic respiratory disease": 186.17440420032395, "Chronic respiratory failure": 30.29644419137296, "Conjunctivitis": 2.320389870670283, "Coronavirus infection": 9.377845584677708, "Cough": 5.18605609126251, "Croup infectious": 95.19822180250073, "Crying": 12.57632252229386, "Cyanosis": 17.84650893129187, "Cystic fibrosis": 10.57188178268562, "Death": 2.1160429983675155, "Dehydration": 2.7773263842175013, "Dermatitis diaper": 38.7021861099303, "Developmental delay": 3.5914138891307537, "Ear infection": 16.310887810141697, "Electrolyte imbalance": 2.367566494330382, "Enterovirus infection": 64.6643884308422, "Failure to thrive": 22.67603657821293, "Febrile convulsion": 4.45483798342582, "Feeding disorder": 4.40225001172453, "Fluid intake reduced": 8.338446272164388, "Fontanelle bulging": 90.0604154444893, "Gastroenteritis": 10.611421096914691, "Gastroenteritis rotavirus": 11.128835654804124, "Gastroenteritis viral": 3.5622295088234366, "Gastrooesophageal reflux disease": 3.5512547960246343, "Gastrostomy": 16.171757107267304, "H1N1 influenza": 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saturation decreased": 8.98244744297829, "Pallor": 5.311443554115138, "Parainfluenzae virus infection": 40.67945089811968, "Pneumonia": 5.177931686915091, "Pneumonia aspiration": 2.6983985035534634, "Pneumonia bacterial": 3.4167918356732008, "Pneumonia respiratory syncytial viral": 607.4683976830942, "Pneumonia viral": 25.409601766476616, "Pneumothorax": 3.628023829160131, "Poor feeding infant": 34.438343270752696, "Product dose omission issue": 4.635985816843809, "Pulmonary congestion": 4.909881061699684, "Pulmonary hypertension": 5.552956579381494, "Rales": 3.298053290958874, "Respiration abnormal": 4.112746645026419, "Respiratory arrest": 5.939632004807681, "Respiratory disorder": 10.79803298265356, "Respiratory distress": 17.72830835778787, "Respiratory failure": 7.962491396878717, "Respiratory rate increased": 8.809528506131956, "Respiratory syncytial virus bronchiolitis": 12149.277701894092, "Respiratory syncytial virus bronchitis": 2095.93597987918, "Respiratory syncytial virus infection": 2194.961432432083, "Respiratory syncytial virus test positive": 4984.922324601891, "Respiratory tract congestion": 20.37157531997831, "Respiratory tract infection": 15.948728751093402, "Respiratory tract infection viral": 28.712924966134054, "Rhinitis": 6.431888217628884, "Rhinorrhoea": 7.858839977660247, "Rhinovirus infection": 180.1941662888103, "Rotavirus infection": 18.476268971275363, "Secretion discharge": 4.205386222193698, "Seizure": 2.067905274033656, "Selective eating disorder": 41.05370331781002, "Staphylococcal infection": 2.301063998896947, "Stridor": 9.228466856804358, "Sudden death": 4.802617068440646, "Sudden infant death syndrome": 133.33402067364332, "Surgery": 3.8455500331883306, "Tachypnoea": 5.781712525774465, "Tonsillitis": 4.117114807066312, "Tracheitis": 36.95692845609894, "Umbilical hernia": 8.953664599720785, "Unevaluable event": 31.67530204354482, "Upper respiratory tract infection": 12.008213232847556, "Upper respiratory tract inflammation": 21.10220807567137, "Use of accessory respiratory muscles": 85.76848509527693, "Varicella": 2.6001533191040567, "Viral infection": 20.80593853914922, "Viral upper respiratory tract infection": 14.998847410228054, "Wheezing": 9.46888172034534}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1043.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1043.json
index 572676df342..bb29c2cdf1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1043.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1043.json
@@ -1 +1 @@
-{"Drug resistance ": 254.29199408251824, "Off label use ": 23.720787754991523}
\ No newline at end of file
+{"Bronchiolitis": 778.7056142568129, "Bronchitis": 12.842557096153971, "Cough": 3.714614937402436, "Crying": 9.757838990373523, "Cyanosis": 15.047732238951893, "Febrile convulsion": 104.20822628646177, "Gait disturbance": 2.308233809316597, "Gastroenteritis": 49.50427881908052, "Hypotonia": 15.49436104679001, "Hypotonic-hyporesponsive episode": 157.4062306832819, "Nasopharyngitis": 5.439013643771641, "Otitis media": 171.24733030314465, "Pharyngitis": 41.23229230924512, "Pharyngotonsillitis": 1141.1071288927312, "Pneumonia": 2.5341077722995995, "Pyrexia": 3.217042861448929, "Rhinorrhoea": 6.683469626978567, "Seizure": 2.5735260394938924, "Tonsillitis": 50.87302756135354, "Upper respiratory tract infection": 36.55224574583768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1044.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1044.json
index ae58f67c4ea..37c9257d249 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1044.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1044.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 5.1277662364354, "Abdominal distension ": 11.791425764328764, "Abdominal pain upper ": 2.1040598194208058, "Anxiety ": 2.4321796793193515, "Apathy ": 24.39302440109842, "Back pain ": 3.826840705334224, "Balance disorder ": 5.616529568335016, "Body temperature increased ": 3.9373600003290776, "Brain fog ": 23.49891729025513, "Compression fracture ": 119.8384336569958, "Contusion ": 4.422667764151881, "Cough ": 2.187113554942866, "Defaecation urgency ": 132.73646066353425, "Depressed level of consciousness ": 7.300647887370133, "Depression ": 2.2494264745268424, "Eructation ": 49.804557220690185, "Faeces hard ": 250.41818787072893, "Fall ": 2.483299481729722, "Feeding disorder ": 22.985848965815062, "Feeling abnormal ": 5.367405670299214, "Flatulence ": 24.45448797963413, "Frequent bowel movements ": 42.81589314851118, "Gastrointestinal stoma complication ": 831.550395288055, "Gastrointestinal stoma output abnormal ": 9578.639330348751, "Hiccups ": 52.586467848788864, "Hot flush ": 6.6337027206923445, "Hypersomnia ": 19.10133681389019, "Insomnia ": 2.7702106056602864, "Intestinal obstruction ": 49.144941412122165, "Joint swelling ": 4.895485853124828, "Lethargy ": 5.601716806197969, "Lumbar vertebral fracture ": 132.1628924135092}
\ No newline at end of file
+{"Acute graft versus host disease": 9.556973829554424, "Acute kidney injury": 4.632972201997329, "Aplasia pure red cell": 9.435409341152765, "Aspergillus infection": 13.91952464524402, "Bacterial infection": 4.539085156493998, "Blood creatinine increased": 3.813735773258565, "Blood magnesium decreased": 14.473511721623495, "Bronchopulmonary aspergillosis": 15.253063593946726, "Candida infection": 13.267752348376414, "Complications of transplanted kidney": 74.50705244939448, "Contraindicated product administered": 2.7845585326378406, "Cytomegalovirus infection": 15.157237278663734, "Cytomegalovirus infection reactivation": 11.550805057576676, "Cytomegalovirus viraemia": 20.03520013050089, "Delirium": 3.1871101315817185, "Diffuse large B-cell lymphoma": 9.65208618744716, "Drug interaction": 15.81470973551902, "Drug level below therapeutic": 20.324218023469687, "Drug level decreased": 20.65286278363047, "Drug level increased": 28.988626951777054, "Drug-induced liver injury": 2.4391465791004365, "Electrocardiogram QT prolonged": 3.153313608304094, "Electrolyte imbalance": 11.05953188385152, "Encephalopathy": 3.0534522890184603, "Epstein-Barr virus infection": 14.84013748743892, "Foetal exposure during pregnancy": 2.2210328204057324, "Fungal infection": 6.372367484662919, "Gastric ulcer": 3.8335378448649, "Graft versus host disease": 26.73033623851588, "Graft versus host disease in gastrointestinal tract": 27.46189931928016, "Hepatotoxicity": 2.315869496282281, "Hiccups": 7.0034951531256535, "Hyperkalaemia": 9.201204064119976, "Immunosuppressant drug level decreased": 248.0418648889223, "Immunosuppressant drug level increased": 264.6432124536741, "Kidney transplant rejection": 43.66762927488129, "Labelled drug-drug interaction medication error": 8.395399340523921, "Leukopenia": 2.2101277584479933, "Liver transplant rejection": 108.23083641779152, "Mental status changes": 4.740266931794532, "Multiple organ dysfunction syndrome": 2.2936034813393302, "Nephropathy toxic": 26.15257354673421, "Neurotoxicity": 11.378608573956864, "Nocardiosis": 66.56801510090207, "Oesophageal candidiasis": 15.158382280624116, "Off label use": 2.2965601647263867, "Peritonitis": 9.178477286389231, "Polyomavirus-associated nephropathy": 70.68430142199296, "Post transplant lymphoproliferative disorder": 23.09285420269395, "Posterior reversible encephalopathy syndrome": 13.802264725416752, "Premature baby": 6.992214468985721, "Premature delivery": 3.789818494331719, "Renal impairment": 4.091469548624541, "Renal tubular necrosis": 6.980908071945522, "Respiratory failure": 2.0172091985146725, "Scedosporium infection": 118.72095024196096, "Septic shock": 2.38036609686691, "Skin lesion": 3.007428543531706, "Squamous cell carcinoma of skin": 21.68212317763691, "Staphylococcal infection": 3.4611760965196705, "Thrombotic microangiopathy": 24.854055910318632, "Toxicity to various agents": 4.897400962091449, "Transplant rejection": 48.36680142436104, "Tuberculosis": 7.325966222814844, "Varicella zoster virus infection": 22.159620992696937}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1045.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1045.json
index c3067556bf3..7105f7599a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1045.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1045.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.595551872054118, "Fall ": 4.650298968905808}
\ No newline at end of file
+{"Basal cell carcinoma": 45.30284295792817, "Blood pressure increased": 2.6807247592811034, "Cardiac failure": 6.523497642483212, "Drug interaction": 2.4814046230106723, "Malignant melanoma": 27.122319976752102, "Respiratory syncytial virus infection": 47.11616481082915, "Toxicity to various agents": 3.4816910427180288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1046.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1046.json
index b9a7a393df3..0e3eb20422b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1046.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1046.json
@@ -1 +1 @@
-{"Anaemia ": 2.7779060769933666, "Cytopenia ": 19.408090829709096, "Decreased appetite ": 7.484137183796419, "Diarrhoea ": 2.6546182154293465, "Febrile neutropenia ": 2.600021384872554, "Gastrointestinal disorder ": 3.3255390937417397, "Granulocyte count decreased ": 35.40515316876338, "Haemoglobin decreased ": 6.601374361586855, "Interstitial lung disease ": 5.915587462163558, "Leukopenia ": 9.691648078360767, "Malignant neoplasm progression ": 2.341822028937473, "Myelosuppression ": 98.16820857735608, "Neuropathy peripheral ": 6.868056683700585, "Neutropenia ": 8.98674136639577, "Neutrophil count decreased ": 46.5933605454822, "Platelet count decreased ": 24.203811143532118, "Red blood cell count decreased ": 15.814446673867652, "Renal impairment ": 2.069044047804484, "Thrombocytopenia ": 5.371263958732753, "White blood cell count decreased ": 32.39378602539339}
\ No newline at end of file
+{"Acute kidney injury": 6.895030961377874, "Cardiac failure": 15.078673608076889, "Dyspnoea": 2.085228787503045, "Syncope": 8.648516371117791}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1047.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1047.json
index 4c3eca71bf8..6be503ff8da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1047.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1047.json
@@ -1 +1 @@
-{"Angioedema ": 4.852526923056708, "Blood creatinine increased ": 9.11414697954562, "Blood potassium increased ": 26.68296229833696, "Blood pressure inadequately controlled ": 143.43369787291007, "Blood pressure increased ": 8.85084234412658, "Cerebrovascular accident ": 2.6343060876584965, "Drug interaction ": 2.1225108539429067, "Hyperkalaemia ": 6.718978229010968, "Hypertension ": 4.070054403352931, "Palpitations ": 2.2555678102262497}
\ No newline at end of file
+{"Asthenia": 2.0297665972138086, "Cardiac failure": 2.1326734237511453, "Death": 6.644593702886772, "Disease progression": 2.428502090800721, "Dysphagia": 5.337199756249735, "General physical health deterioration": 2.256908028393501, "Hospitalisation": 3.607536407949742, "Hyperkeratosis": 31.339646439611634, "Hyperpyrexia": 16.748828454881412, "Malignant melanoma": 26.51803200313268, "Malignant neoplasm progression": 10.074603566996371, "Metastases to central nervous system": 35.97684734159338, "Metastases to lung": 10.738587887181808, "Metastatic malignant melanoma": 127.91629892137396, "Neutropenia": 2.0196736576082213, "Palmoplantar keratoderma": 337.1039155598279, "Product use in unapproved indication": 2.324539554268213, "Pyrexia": 3.2416631478560416, "Skin papilloma": 56.4605016308825, "Uveitis": 33.144610733618265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1048.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1048.json
index 3d84bfefe76..7c744f1f9f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1048.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1048.json
@@ -1 +1 @@
-{"Anaemia ": 20.976499490462054, "Blood creatinine increased ": 20.323346852892215, "Drug interaction ": 15.697916934734002, "Pruritus ": 2.5581591849985323, "Rash ": 5.4578924914558415, "Thrombocytopenia ": 4.147390809311243}
\ No newline at end of file
+{"Acne": 3.9817893001292526, "Acquired gene mutation": 14.86060427971434, "Aplastic anaemia": 2.4584023089024867, "Atelectasis": 2.37771660757051, "Blood creatine phosphokinase increased": 2.6123542299220905, "Blood sodium decreased": 2.0135075514031517, "Body height decreased": 4.185769001700461, "Brain neoplasm": 6.644883522038496, "Brain oedema": 3.1302435548088, "Carcinoembryonic antigen increased": 42.61673227311675, "Cardiac dysfunction": 12.327542922884517, "Cardiac failure": 8.52071036093018, "Cardiac failure acute": 5.251452961857661, "Cardiac failure chronic": 3.822153430360925, "Cardiac failure congestive": 2.507312373537516, "Cardiac tamponade": 5.463955370606241, "Cardiomyopathy": 5.997049806132496, "Cardiotoxicity": 4.967330641045299, "Cerebral infarction": 3.4034875300558856, "Conjunctivitis": 2.064826211216725, "Cutaneous vasculitis": 3.395635663936643, "Decreased appetite": 3.3204262462477563, "Deep vein thrombosis": 2.185114127131098, "Dermatitis": 3.8455674481922655, "Dermatitis acneiform": 23.26756462073814, "Diarrhoea": 3.4767849022646558, "Dilated cardiomyopathy": 3.147025142157053, "Disease progression": 2.480300105556443, "Drug eruption": 2.929434774742854, "Drug resistance": 4.47367629226466, "Dry eye": 2.448772686386256, "Dry skin": 9.05282648504712, "EGFR gene mutation": 44.62231329418593, "Ejection fraction decreased": 11.295137675058209, "Electrocardiogram QT prolonged": 14.629520935685772, "Erythema multiforme": 5.641609336630526, "Feeding disorder": 3.094787333093971, "Femur fracture": 2.416476449857122, "Fracture": 2.645747600499752, "Haematotoxicity": 2.965636279316429, "Haemoptysis": 2.417693027600344, "Heart failure with reduced ejection fraction": 28.31332695155776, "Hepatic function abnormal": 2.429688221568133, "Hypophagia": 2.2703870435921254, "Interstitial lung disease": 47.55755804580372, "Keratitis": 19.58168248049645, "Liver disorder": 3.2453349166959704, "Long QT syndrome": 15.736520794768186, "Lung disorder": 8.477348622658056, "Lung infiltration": 2.1073581419576777, "Lung neoplasm malignant": 8.157281600255411, "Lung opacity": 22.832835082362784, "Lymphangiosis carcinomatosa": 54.89363797859607, "Malignant neoplasm progression": 23.07686060217942, "Malignant pleural effusion": 16.791500949232315, "Metastases to bone": 16.023886140613364, "Metastases to central nervous system": 50.12358179331599, "Metastases to liver": 7.575937267365127, "Metastases to lung": 6.587186732999116, "Metastases to lymph nodes": 7.505266377899103, "Metastases to meninges": 80.14189619352831, "Metastases to pleura": 27.48685934398338, "Metastases to spine": 15.279311033087652, "Metastasis": 19.640796287052037, "Mouth ulceration": 2.0692533413201595, "Mucosal disorder": 6.642481227070001, "Mucosal inflammation": 3.283513389119108, "Myelosuppression": 2.6984300502336844, "Nail bed inflammation": 116.04007033133642, "Nail disorder": 27.50616212964865, "Neoplasm progression": 2.3573911721813654, "Neutrophil count decreased": 2.1104475114733785, "No adverse event": 2.7729909872459397, "Non-small cell lung cancer": 11.60562978054623, "Onychoclasis": 37.42974064973691, "Paronychia": 140.35659557675618, "Pericardial effusion": 3.709610246804262, "Platelet count decreased": 4.392614564417044, "Pleural effusion": 10.053933699554422, "Pneumocystis jirovecii pneumonia": 2.552700740824178, "Pneumonia aspiration": 2.26254680295525, "Pneumonia bacterial": 8.470957817758496, "Pneumonitis": 41.91260667605256, "Pneumothorax": 6.265809169077893, "Pulmonary alveolar haemorrhage": 4.041715289510191, "Pulmonary embolism": 3.061761150380486, "Pulmonary mass": 2.911086503171793, "Pulmonary oedema": 2.7454816572585274, "Pulmonary toxicity": 63.23391072785357, "Pustule": 2.946345586943139, "Rash": 2.3210180146443222, "Recurrent cancer": 10.40935008333442, "Respiratory failure": 2.934155550665392, "SARS-CoV-2 test negative": 12.007149456124772, "Skin disorder": 5.413889254239975, "Skin fissures": 16.32960554174431, "Skin toxicity": 7.815781450501984, "Skin ulcer": 2.032602812468616, "Small cell lung cancer": 21.49811021775693, "Stomatitis": 5.472740746696174, "Taste disorder": 3.310603632309159, "Thrombocytopenia": 3.954335554020756, "Torsade de pointes": 2.3862463935662435, "Tumour marker increased": 11.272312365499168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1049.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1049.json
index 6a39b562412..a3d585a49b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1049.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1049.json
@@ -1 +1 @@
-{"Stevens-Johnson syndrome ": 235.45859548184885}
\ No newline at end of file
+{"Injection site pain": 2.943954252386543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/105.json
index d1e79fe7432..86bf16dfaef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/105.json
@@ -1 +1 @@
-{"Abdominal distension ": 18.733780709178777, "Abdominal pain ": 4.990047295506409, "Actinic keratosis ": 3.2158832903036134, "Activated partial thromboplastin time prolonged ": 97.07337389774403, "Anaemia ": 8.111480776149696, "Analgesic therapy ": 1162.0121286805934, "Antacid therapy ": 4857.661048703754, "Anti-erythrocyte antibody ": 164.68195977219898, "Anti-erythropoietin antibody ": 63.4887630842544, "Anti-erythropoietin antibody negative ": 92.8942963410077, "Anti-erythropoietin antibody positive ": 190.2727245056481, "Antibody test positive ": 12.932783273162114, "Anticoagulant therapy ": 382.90548999125576, "Aortic arteriosclerosis ": 3.055648834068608, "Aortic stenosis ": 132.38306226231197, "Aortic valve incompetence ": 2.2528687802310547, "Aplasia pure red cell ": 171.87568015645115, "Aplastic anaemia ": 3.436135630868969, "Appendicitis ": 170.42240186197307, "Appendicolith ": 2225.6922003734244, "Arteriovenous fistula thrombosis ": 31.458975001674865, "Ascites ": 43.55920766000221, "Aspartate aminotransferase increased ": 4.0838081395885, "Aspiration ": 7.15716231469067, "Azotaemia ": 4.719695428709936, "Bacterial infection ": 77.4887290005829, "Bacteroides infection ": 2322.944841193785, "Blood calcium increased ": 9.826084718517018, "Blood cholesterol increased ": 20.11311616993462, "Blood parathyroid hormone increased ": 8.433325458690241, "Blood phosphorus increased ": 413.8302060432384, "Blood product transfusion dependent ": 25.08568241506981, "Blood test abnormal ": 8.900080268313706, "Blood uric acid increased ": 128.66668450380837, "Bone marrow disorder ": 5.484481087273288, "Bone marrow failure ": 11.299530211324427, "Bronchiectasis ": 10.711735328415182, "Calciphylaxis ": 6.873223493485576, "Cardiac output decreased ": 13.14843724982483, "Cardiogenic shock ": 90.56404506888036, "Carotid artery stenosis ": 3.039208306871444, "Caudal regression syndrome ": 38.94846739598081, "Chronic obstructive pulmonary disease ": 11.385967528329813, "Complications of transplanted kidney ": 22.16684485682795, "Condition aggravated ": 3.9780745604780954, "Constipation ": 9.739752824389711, "Death ": 8.113063000537679, "Delayed graft function ": 47.87820750073544, "Device difficult to use ": 32.496851461792616, "Diabetes mellitus ": 14.592634890733809, "Dialysis ": 59.39546002226727, "Diffuse alopecia ": 4.59568690268406, "Diverticulum intestinal ": 4.80085744929904, "Drug dose omission by device ": 4.725081980372287, "Drug hypersensitivity ": 8.809794231668283, "Drug intolerance ": 7.090382748370273, "Drug specific antibody ": 9.059478472726886, "Drug specific antibody absent ": 136.5510687603988, "Drug specific antibody present ": 10.780699717297322, "Drug therapy ": 712.9981526898817, "Dry mouth ": 6.034141166184418, "End stage renal disease ": 2.4100481030685983, "Erythropoiesis abnormal ": 36.462003295443765, "General physical health deterioration ": 11.250323339128803, "Haematocrit decreased ": 2.703816192310017, "Haemodialysis ": 117.31252584383982, "Haemoglobin abnormal ": 46.35016574269515, "Haemoglobin decreased ": 9.276834811757764, "Haemoglobin increased ": 15.465779206734448, "Hip fracture ": 2.906334527403862, "Hospitalisation ": 19.47206006717056, "Hyperparathyroidism ": 14.1125932972008, "Hyperparathyroidism secondary ": 13.352019944588278, "Hyperphosphataemia ": 323.6734064920491, "Hypervolaemia ": 3.3281553747046213, "Hyponatraemia ": 10.97572617095042, "Hypophosphataemia ": 62.26964528755798, "Incorrect route of product administration ": 15.691171974007732, "Injection site haemorrhage ": 3.259871913207012, "Intentional product misuse ": 4.96069783902575, "Iron deficiency ": 24.004628738543406, "Iron overload ": 11.939888168039078, "Kidney transplant rejection ": 5.013823535790412, "Laboratory test abnormal ": 2.792296422174614, "Multiple organ dysfunction syndrome ": 13.43277067963261, "Myelodysplastic syndrome ": 11.957347995660667, "Myelodysplastic syndrome with single lineage dysplasia ": 75.17752483159329, "Myelofibrosis ": 2.8832966867905294, "Neutralising antibodies positive ": 38.11223478447088, "Non-neutralising antibodies positive ": 396.30123387811545, "Normochromic normocytic anaemia ": 17.120467205408225, "Normocytic anaemia ": 3.0546007557742643, "Occult blood positive ": 2.7448656331196544, "Pancytopenia ": 2.021827558114906, "Parvovirus B19 infection ": 23.237744443252264, "Peritoneal dialysis ": 88.78259271561392, "Peritonitis ": 4.300743857641797, "Peritonitis bacterial ": 9.572433499343148, "Platelet count abnormal ": 3.3385415789168094, "Polycythaemia ": 3.3767239497890564, "Product storage error ": 3.653994517612783, "Red blood cell abnormality ": 8.72464495417338, "Rehabilitation therapy ": 7.602209643991872, "Renal disorder ": 2.015231458544135, "Renal transplant ": 44.59580225320743, "Reticulocyte count abnormal ": 193.21643531882725, "Reticulocyte count decreased ": 111.98983190628913, "Reticulocytopenia ": 66.72117700180749, "Sepsis ": 6.611824911750844, "Serum ferritin increased ": 4.796041499913586, "Splenomegaly ": 2.400867898159191, "Stress ": 14.698714259418422, "Supraventricular tachycardia ": 3.687987253926973, "Terminal state ": 12.19747309376526, "Therapeutic response decreased ": 18.615198280850112, "Therapy non-responder ": 3.1108143398791457, "Transfusion ": 14.3272725313101, "Transfusion reaction ": 25.49812255368961, "Transplant ": 72.57826578094708, "Transplant rejection ": 2.1254821356796505, "Unevaluable event ": 3.0465677840202483, "Urine odour abnormal ": 3.186975124658649, "Ventricular fibrillation ": 8.992294284558822, "Vitamin B12 deficiency ": 3.036715902304327}
\ No newline at end of file
+{"Abdominal discomfort": 11.366995864393528, "Alopecia": 11.53889758522827, "Anti-cyclic citrullinated peptide antibody": 18.884061263319705, "Anti-cyclic citrullinated peptide antibody positive": 55.833767501792, "Arthropathy": 21.884931133281384, "Atelectasis": 27.950465274634503, "Autoimmune disorder": 8.58288867959757, "Barrett's oesophagus": 72.22825313802474, "Blister": 20.85342885254644, "Blood cholesterol increased": 3.198187677916212, "Bursitis": 6.845969820040452, "C-reactive protein abnormal": 8.214585091180096, "Computerised tomogram thorax": 490.7821148960112, "Computerised tomogram thorax abnormal": 127.24802931445866, "Condition aggravated": 6.533140997070747, "Confusional state": 8.304303866771997, "Contraindicated product administered": 19.48181001863859, "Contusion": 17.2122099043093, "Deep vein thrombosis postoperative": 27.82150165726569, "Discomfort": 22.677592482980696, "Drug hypersensitivity": 2.810212022339558, "Drug intolerance": 7.682090277745229, "Duodenal ulcer perforation": 90.4668098392763, "Dyspepsia": 2.4009209694429616, "Dyspnoea": 2.6451684101365225, "Erosive oesophagitis": 194.66640392393444, "Eructation": 14.993387411042413, "Facet joint syndrome": 9.568040256098945, "Folliculitis": 67.6329721027273, "Gastrointestinal disorder": 21.183754298772264, "General physical health deterioration": 12.675750125958908, "Glossodynia": 31.26092587474628, "Haematemesis": 7.128287150578749, "Haematoma": 2.2415298008861395, "Hand deformity": 45.12003483895201, "Helicobacter infection": 82.99315107728042, "Hepatic enzyme increased": 16.99299136086368, "Hypersensitivity": 8.025801396188982, "Hypoxia": 3.6506345400712936, "Ill-defined disorder": 36.56523764826924, "Impaired healing": 50.58495734397461, "Infection": 12.10962647505432, "Infusion related reaction": 19.524010325729176, "Injury": 17.917157806599448, "Irritable bowel syndrome": 12.84806847105128, "Lower respiratory tract infection": 3.8057202539450303, "Muscle injury": 10.68946862316932, "Oesophageal haemorrhage": 221.55515272500247, "Oesophageal mucosal dissection": 3985.207007354716, "Oropharyngeal discomfort": 10.805707007532696, "Regurgitation": 58.52446894248711, "Respiratory syncytial virus infection": 11.862777383961882, "Vitamin B12 deficiency": 48.45176838222381}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1050.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1050.json
index c54b7019afc..cd40b4ab5b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1050.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1050.json
@@ -1 +1 @@
-{"Drug resistance ": 148.29231174476035, "Therapeutic response decreased ": 129.52114819956003}
\ No newline at end of file
+{"Abnormal behaviour": 114.07796883334296, "Abnormal faeces": 3.903878360679762, "Abortion": 3.115044874824876, "Abortion missed": 5.87576722310144, "Acute hepatic failure": 3.425741380328815, "Acute respiratory distress syndrome": 6.679424789011901, "Aggression": 3.032944017602504, "Agitation": 5.3963347810506255, "Altered state of consciousness": 9.507906163289748, "Anaphylactoid reaction": 3.8301099961695777, "Angle closure glaucoma": 2.790985482849434, "Apgar score low": 6.689197087648888, "Autoimmune haemolytic anaemia": 2.522531017769136, "Blister rupture": 10.521377997928758, "Blood creatine phosphokinase increased": 3.2068567682790445, "Body temperature decreased": 3.3078819957721097, "Brain death": 4.459372039558303, "Cardiac failure acute": 7.800588409694852, "Cardiac tamponade": 2.7500536366681376, "Cardio-respiratory arrest": 2.0566040796984324, "Chest X-ray abnormal": 2.563153017956776, "Cholestasis": 3.3356283298895386, "Chromaturia": 5.318184432389533, "Colitis ischaemic": 16.600111831222005, "Confusional state": 2.8511448160267747, "Conjunctival hyperaemia": 2.0502722129183675, "Conjunctivitis": 2.129218440977306, "Conversion disorder": 6.234781747084353, "Creatinine renal clearance decreased": 2.254653211398667, "Crying": 2.540461978700807, "Dehydration": 2.059077345786719, "Delirium": 17.935615857079814, "Delirium febrile": 48.52835963855505, "Delusion": 14.63523803697848, "Depressed level of consciousness": 2.425376970611416, "Dermatitis allergic": 2.201679330322688, "Dermatitis bullous": 2.2472244374861376, "Diarrhoea haemorrhagic": 3.9338235951842746, "Disorientation": 3.3320223622380887, "Disseminated intravascular coagulation": 3.397094585647697, "Drug eruption": 6.608636102100278, "Drug-induced liver injury": 2.847109488466764, "Duodenal ulcer": 2.650652489980656, "Duodenal ulcer haemorrhage": 3.357202942013878, "Encephalitis": 4.245496048573253, "Encephalopathy": 5.498466830890743, "Enterocolitis haemorrhagic": 85.3151506856073, "Erythema multiforme": 8.721989369917017, "Erythema nodosum": 2.1780017781447123, "Eye movement disorder": 2.1886468204294136, "Faeces discoloured": 2.5203141312227006, "Fear": 4.375754331430009, "Foetal death": 5.341308159496689, "H1N1 influenza": 108.54891770019869, "Haematemesis": 3.663660307644783, "Haematuria": 2.1216630045715763, "Hallucination": 20.317079053973675, "Hallucination, auditory": 11.95068004286625, "Hallucination, visual": 6.762625765982687, "Hallucinations, mixed": 7.224798356858723, "Henoch-Schonlein purpura": 4.087286149918017, "Hepatic cytolysis": 4.7576935499245865, "Hepatic failure": 2.8418831689433293, "Hepatic function abnormal": 7.081140197926548, "Hepatitis": 4.316767633661138, "Hepatitis A": 12.622450927110243, "Hepatitis acute": 5.5508965781441, "Hepatitis cholestatic": 2.060264767255891, "Hepatitis fulminant": 18.87629302680123, "Hypothermia": 13.519531127114258, "Hypoxia": 2.0473521077900894, "Illusion": 4.0243510242320815, "Incoherent": 4.829033897068582, "Influenza": 2.643209913670965, "Influenza A virus test positive": 49.66379759870595, "International normalised ratio increased": 5.235228137226186, "Jaundice": 2.6097438912683906, "Leukopenia": 2.1453146902717446, "Liver disorder": 5.3958315552922365, "Liver function test abnormal": 3.129344253175592, "Loss of consciousness": 3.3550692972889062, "Lower limb fracture": 2.0152148927423266, "Melaena": 3.9500319974423648, "Meningitis": 2.1985142309196237, "Mental disorder": 4.953582762655146, "Multiple organ dysfunction syndrome": 3.639019186038419, "Neurological symptom": 2.036530638883425, "Nightmare": 8.08041709435329, "No adverse event": 11.22079228665147, "Painful respiration": 2.9870078531201028, "Panic attack": 2.862934426803805, "Panic reaction": 3.8643770514106337, "Paranoia": 2.5087993514651235, "Pathogen resistance": 17.821919168165415, "Periorbital swelling": 2.1614824500275764, "Personality change": 2.408148543568479, "Pneumonia": 3.274296567186476, "Pneumonia bacterial": 6.48537805099744, "Pneumonia influenzal": 109.02266483115554, "Pneumonia viral": 4.256901990761142, "Pregnancy": 4.257014348911788, "Premature rupture of membranes": 4.02042901331533, "Proteinuria": 4.573017070850496, "Prothrombin time ratio increased": 31.368353476497735, "Prothrombin time shortened": 6.6192310343218805, "Psychiatric symptom": 7.817796259819365, "Psychomotor hyperactivity": 2.567256030938045, "Psychotic disorder": 3.7222431832637297, "Rash morbilliform": 3.810495463954853, "Respiratory failure": 2.899678028254671, "Restlessness": 3.1185272726100086, "Rhabdomyolysis": 3.450854041752684, "Screaming": 6.345873868592912, "Seizure": 4.228074138257799, "Self-destructive behaviour": 4.547461525569352, "Sepsis": 2.208975105164632, "Septic shock": 2.096432832703791, "Shock": 4.262421730175169, "Skin erosion": 3.457178596653861, "Skin exfoliation": 2.3195155944269445, "Sleep talking": 11.817397149523682, "Sleep terror": 25.045044537462992, "Somnambulism": 7.370116070983693, "Speech disorder": 2.358247846560329, "Staphylococcal sepsis": 4.904903271744077, "Staring": 3.7913434651412032, "Stevens-Johnson syndrome": 8.785857829085096, "Stillbirth": 3.74995180581302, "Strabismus": 4.624468574170573, "Sudden death": 6.505371193564982, "Suicidal behaviour": 3.0178903355472477, "Suicidal ideation": 2.011255180203694, "Supraventricular tachycardia": 2.7166109327417987, "Thinking abnormal": 3.1230174259871117, "Toxic epidermal necrolysis": 7.452641959325338, "Transaminases increased": 2.5257206063569435, "Urine odour abnormal": 25.035341587166027, "Vasculitic rash": 18.249286522458576, "Vomiting": 3.5576626292038136}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1051.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1051.json
index 793366f9671..db186dfa056 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1051.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1051.json
@@ -1 +1 @@
-{"Acute kidney injury ": 3.794996012364297, "Angioedema ": 7.017530788545577, "Asthma ": 2.969908944251255, "Atrioventricular block complete ": 5.830511208547697, "Autonomic neuropathy ": 85.42130020171288, "Blood creatine phosphokinase increased ": 3.496464806514477, "Blood creatinine increased ": 2.3743380964573357, "Blood pressure abnormal ": 4.590611781376902, "Blood pressure decreased ": 3.3554718293230743, "Blood pressure fluctuation ": 3.6105456277226993, "Blood pressure inadequately controlled ": 42.25598979425666, "Blood pressure increased ": 3.3168886646528093, "Blood pressure systolic increased ": 3.729874266038971, "Blood urea increased ": 3.140265540239677, "Bradycardia ": 4.090960621042076, "Cardio-respiratory arrest ": 4.826456496855538, "Chest discomfort ": 3.2618584404812383, "Clostridium difficile infection ": 6.492767959112053, "Clumsiness ": 44.01255712891343, "Cognitive disorder ": 3.492785374209239, "Cough ": 2.746860519454692, "Cranial nerve disorder ": 95.0725410915532, "Drug interaction ": 2.823500108073976, "Drug level increased ": 2.8350645496234783, "Drug reaction with eosinophilia and systemic symptoms ": 2.4107711183112275, "Electrocardiogram abnormal ": 4.918461170090918, "Encephalopathy ": 3.8846470810827474, "Forced expiratory flow decreased ": 2804.388150094649, "Forced vital capacity decreased ": 311.63286284412646, "Full blood count abnormal ": 5.310903785908307, "Giant cell arteritis ": 34.0285107602632, "Heart rate decreased ": 5.281758681616276, "Hypercalcaemia ": 8.75568038213015, "Hyperkalaemia ": 10.287335806164004, "Hypertensive crisis ": 5.356696146564699, "Hypokalaemia ": 2.273463676710508, "Hyponatraemia ": 4.158363038635899, "Hypotension ": 3.092812003639183, "Illness ": 2.153865259770189, "Jaw disorder ": 47.529180325284045, "Left ventricular hypertrophy ": 12.13198423660111, "Loss of personal independence in daily activities ": 4.800037831736784, "Meningitis aseptic ": 12.6570295587455, "Mononeuropathy multiplex ": 120.48405403877672, "Myelitis ": 29.142288020288525, "Nasopharyngitis ": 4.014674871096902, "Oedema peripheral ": 3.0004241882566376, "Oligohydramnios ": 27.02468754792876, "Oliguria ": 5.370400027937494, "Optic neuropathy ": 42.39028228996898, "Oral discomfort ": 5.600585268935812, "Orthostatic hypotension ": 7.027951063427358, "Peripheral sensorimotor neuropathy ": 69.99693825383892, "Peripheral sensory neuropathy ": 15.417019349574757, "Product substitution issue ": 20.64133703091313, "Product use issue ": 3.771594390572568, "Prolonged expiration ": 84.50497864567333, "Proteinuria ": 2.89361043441058, "Pyelonephritis ": 6.255679723179492, "Red blood cell sedimentation rate increased ": 9.898958802959395, "Rhabdomyolysis ": 2.479783272090896, "SARS-CoV-2 test positive ": 3.7698750474433584, "Schizophrenia ": 6.0018915112044855, "Shock ": 3.060508605316859, "Sjogren's syndrome ": 26.32475250699679, "Sleep disorder due to a general medical condition ": 19.626837093032712, "Small fibre neuropathy ": 52.36215712988933, "Therapeutic product effect incomplete ": 5.949670181101318, "Thirst ": 2.6013816464191817, "Toxic epidermal necrolysis ": 2.0374826664606847, "Toxicity to various agents ": 2.565865072581975, "Wheezing ": 5.55756358154325}
\ No newline at end of file
+{"Acute kidney injury": 4.482919413466625, "Dermatitis acneiform": 109.56520027175364, "Diarrhoea": 3.910945204404408, "Drug interaction": 8.112214270459697, "International normalised ratio increased": 8.283980724673425, "Interstitial lung disease": 9.02994101022334, "Rash": 3.125658466136694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1052.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1052.json
index e6b3c364345..3b0f180393b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1052.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1052.json
@@ -1 +1 @@
-{"Accidental overdose ": 2.02270447511109, "Acute myeloid leukaemia ": 4.699236292442226, "Adverse event ": 5.161614581684264, "Agranulocytosis ": 6.893313513070406, "Anaemia ": 2.9944080670356383, "Aphasia ": 2.680491570203874, "Aplastic anaemia ": 15.672726238864222, "Bone marrow failure ": 75.61106524175345, "Brain oedema ": 14.23319789792493, "Cerebral haemorrhage ": 3.040842909308634, "Cholestasis ": 10.202963317414216, "Congenital aplasia ": 35.36698485813653, "Cytomegalovirus infection ": 3.5366449631525554, "Cytopenia ": 6.196162914729093, "Death ": 2.3231587938627483, "Disease progression ": 14.270617859201955, "Disseminated intravascular coagulation ": 4.195681272520557, "Drug eruption ": 4.61005253150852, "Dysphagia ": 3.610513347028712, "Eastern Cooperative Oncology Group performance status worsened ": 65.32830794778262, "Eosinophilia ": 2.0849875804530624, "Epilepsy ": 2.535265624932308, "Erythema multiforme ": 2.1841383531529224, "Febrile bone marrow aplasia ": 61.73465827641543, "Febrile neutropenia ": 4.230445632688407, "Gamma-glutamyltransferase increased ": 3.190926144679189, "Gingival bleeding ": 2.84944494231234, "Glioblastoma ": 118.01532593067084, "Glioblastoma multiforme ": 115.32368295869314, "Haematotoxicity ": 6.996148203447115, "Haemolytic anaemia ": 3.4656108183205223, "Haemorrhage intracranial ": 2.6311387453592663, "Hemiparesis ": 4.2291840001044765, "Hemiplegia ": 7.010506398444517, "Hepatic cytolysis ": 11.07514157520685, "Hepatic function abnormal ": 4.416454579961031, "Hepatocellular injury ": 6.302324232807426, "Hepatotoxicity ": 3.124515286193175, "Interstitial lung disease ": 2.038499602830289, "Intracranial pressure increased ": 8.991560477816442, "Intracranial tumour haemorrhage ": 190.82067344463024, "Jaundice ": 2.058926014751334, "Leukoencephalopathy ": 12.403514266290706, "Leukopenia ": 13.310108986627728, "Liver disorder ": 2.0105244928308434, "Liver injury ": 2.0623628003677035, "Lymphocyte count decreased ": 23.103146852237835, "Lymphopenia ": 16.68107467108862, "Malignant neoplasm progression ": 3.859162467647848, "Mucosal inflammation ": 2.402037579790392, "Multiple organ dysfunction syndrome ": 2.083632835555644, "Myelodysplastic syndrome ": 6.272516643396435, "Myelosuppression ": 8.264221843129564, "Neoplasm progression ": 3.2329657185116214, "Neutropenia ": 8.203848027971022, "Neutrophil count decreased ": 3.685588854368564, "Pancytopenia ": 30.691148650726, "Petechiae ": 4.8169906168205685, "Platelet count decreased ": 6.739882994195853, "Platelet transfusion ": 56.87757181459276, "Pneumocystis jirovecii infection ": 55.0193527045579, "Pneumocystis jirovecii pneumonia ": 30.5036585333217, "Pneumonia ": 2.4987930683595594, "Pneumonia aspiration ": 2.517192178676251, "Pulmonary embolism ": 3.8037498622127535, "Purpura ": 4.512247378692203, "Rash maculo-papular ": 2.7870709919448804, "Recurrent cancer ": 24.556628805135485, "Seizure ": 2.1061033414766097, "Sepsis ": 6.076095993819735, "Septic shock ": 2.1913939740298494, "Stevens-Johnson syndrome ": 7.510492167622416, "Surgery ": 2.435043475799687, "Thrombocytopenia ": 22.98093250697276, "Toxic epidermal necrolysis ": 4.9508593319439935, "Toxic skin eruption ": 5.32718600065986, "White blood cell count decreased ": 4.699609438640698}
\ No newline at end of file
+{"Abdominal tenderness": 2.386278148493243, "Acute coronary syndrome": 5.481912205131358, "Acute lymphocytic leukaemia": 7.4841078068340385, "Acute myocardial infarction": 6.658241906034445, "Alanine aminotransferase increased": 3.007717441354025, "Amylase increased": 17.280760353425762, "Anaemia": 2.0366614631265145, "Angina pectoris": 6.415646484749315, "Angina unstable": 5.9346236283024, "Angiopathy": 8.541266759506541, "Anxiety": 3.0169565839092174, "Aortic aneurysm": 2.6647182610087445, "Aortic arteriosclerosis": 11.14357242402703, "Aortic stenosis": 4.971231229658176, "Aplastic anaemia": 2.0940825800500904, "Arterial disorder": 42.11721586106293, "Arterial occlusive disease": 13.054167595689412, "Arterial stenosis": 28.637597958323, "Arterial thrombosis": 5.012696767103374, "Arteriosclerosis": 80.4511118495703, "Arteriosclerosis coronary artery": 6.378952193153356, "Arteriospasm coronary": 3.099328238618958, "Arteritis": 16.568050196726247, "Aspartate aminotransferase increased": 2.5271934669918257, "Atelectasis": 2.114976600854538, "Atrial fibrillation": 3.4703343012533105, "Autoimmune thyroiditis": 2.619906398452732, "Benign prostatic hyperplasia": 2.054741247569726, "Bilirubin conjugated increased": 3.171039464239067, "Blast cell crisis": 65.77579057403236, "Blast crisis in myelogenous leukaemia": 277.42484462397425, "Blood bilirubin increased": 12.352071066343887, "Blood bilirubin unconjugated increased": 16.729017198398083, "Bone marrow failure": 8.898074597962633, "Bone pain": 2.186145977275645, "Brain natriuretic peptide increased": 3.122998259446893, "Cardiac failure": 2.794563781033331, "Cardiac tamponade": 4.11308373402036, "Cardiomegaly": 2.980123762641798, "Carotid arteriosclerosis": 34.8886891616689, "Carotid artery disease": 12.28187439221012, "Carotid artery occlusion": 12.772053013832174, "Carotid artery stenosis": 73.37185286760841, "Cerebral artery occlusion": 11.71130004285754, "Cerebral artery stenosis": 77.24234012237976, "Cerebral infarction": 8.41923389093852, "Cerebrovascular accident": 3.7436177998646585, "Cholecystitis acute": 2.670025341130067, "Chronic myeloid leukaemia": 172.43835615866848, "Chronic myeloid leukaemia recurrent": 87.3314048498061, "Chronic myeloid leukaemia transformation": 260.01300179730964, "Complex regional pain syndrome": 5.616529427675848, "Concomitant disease aggravated": 9.479186389539391, "Concomitant disease progression": 13.893238797132778, "Coronary artery disease": 11.217716273996093, "Coronary artery occlusion": 10.819215272565833, "Coronary artery stenosis": 15.071508438671913, "Cytogenetic analysis abnormal": 104.50752791423832, "Cytopenia": 7.470764245920069, "Death": 2.1815789879872884, "Diabetes mellitus": 5.09492732077336, "Diastolic dysfunction": 4.367754092996629, "Drug resistance": 2.747156827283987, "Dry skin": 3.0858213151396257, "Dyslalia": 6.117977188348803, "Dyslipidaemia": 6.694980007114304, "Electrocardiogram QT prolonged": 12.343597638762292, "Emotional distress": 7.997504827632006, "Essential hypertension": 7.443647461291658, "Fluid retention": 2.6208479182434354, "Full blood count decreased": 4.369205166795656, "Gamma-glutamyltransferase increased": 2.207886265208566, "Gangrene": 13.01497844242736, "Gastrointestinal stromal tumour": 5.130809918818825, "Gene mutation identification test positive": 96.45183951585608, "Glucose tolerance impaired": 3.887708493428753, "Goitre": 2.5519496044010195, "Haematocrit decreased": 2.511156387831171, "Haematotoxicity": 5.448402478505148, "Haemoglobin decreased": 2.334511109191599, "Hemiplegia": 3.5207974447514374, "Hepatotoxicity": 4.890038492629433, "Hyperbilirubinaemia": 7.652951687792893, "Hypercholesterolaemia": 9.74040015134888, "Hyperlipidaemia": 7.027847791522514, "Hypertriglyceridaemia": 2.074864431449301, "Infarction": 5.290067773914355, "Injury": 20.57952569724656, "Intermittent claudication": 138.08033710077143, "Intervertebral disc degeneration": 2.5137973753781053, "Intervertebral disc protrusion": 2.01136342106698, "Iron deficiency anaemia": 3.2040630964327983, "Ischaemia": 7.442627647016176, "Ischaemic cardiomyopathy": 4.208693724799727, "Ischaemic stroke": 4.6547715196422725, "Jaundice": 2.349192378589306, "Lactose intolerance": 6.415649433206307, "Left ventricular dysfunction": 2.6676142016898914, "Left ventricular hypertrophy": 6.119246912935201, "Leukaemia": 2.132192196421577, "Leukaemia recurrent": 16.501581781244955, "Leukocytosis": 4.132781174459719, "Lipase increased": 32.00286633440593, "Liver disorder": 2.63751722811759, "Liver function test increased": 2.099504175613032, "Malignant neoplasm progression": 4.432011216874221, "Mitral valve incompetence": 6.2551679050093405, "Myelodysplastic syndrome": 2.225191691122253, "Myocardial infarction": 4.503051515932873, "Myocardial ischaemia": 8.117089601181158, "Nasal oedema": 5.412061479712865, "Necrosis": 5.091975432360358, "Oncologic complication": 42.07626726820191, "Pancreatic enzymes increased": 8.12767872220955, "Pancreatitis": 8.25169786910044, "Pancreatitis acute": 4.088881982234512, "Pancytopenia": 6.348060125713251, "Papilloedema": 2.919336754881121, "Paternal exposure during pregnancy": 15.183557162608146, "Pericardial effusion": 8.402646445166855, "Periorbital oedema": 2.5761675493661222, "Peripheral arterial occlusive disease": 239.27440434128096, "Peripheral artery occlusion": 55.3983701859738, "Peripheral artery stenosis": 186.3656410130432, "Peripheral artery thrombosis": 10.040468928137072, "Peripheral ischaemia": 10.610451265862512, "Peripheral vascular disorder": 25.990292032355544, "Philadelphia chromosome positive": 41.0443062034632, "Platelet count decreased": 4.233411110672991, "Platelet count increased": 4.554184603347139, "Pleural effusion": 7.85958626920716, "Pleurisy": 2.552552778392968, "Pulmonary hypertension": 2.275414375557695, "Pulmonary oedema": 2.1490143394567154, "Renal artery stenosis": 9.94499183112089, "Second primary malignancy": 36.742059137578224, "Sensory loss": 2.206295927552624, "Skin ulcer": 2.8541279772025057, "Splenomegaly": 4.731647066417034, "Stenosis": 11.208972007106675, "Supraventricular extrasystoles": 5.320197491737713, "Therapeutic response decreased": 2.204509276585839, "Therapy non-responder": 2.465877116490217, "Thrombocytopenia": 3.9548840244664216, "Thrombocytosis": 8.86397905567226, "Transaminases increased": 2.405306441677729, "Transient ischaemic attack": 4.39049241310469, "Tricuspid valve incompetence": 8.21797017104777, "Type 2 diabetes mellitus": 2.288853812564261, "Ulcer": 2.1698387238703507, "Vascular occlusion": 7.112238232888209, "Vascular stenosis": 38.017779355632776, "Ventricular extrasystoles": 2.0341742257925133, "Vertebral artery stenosis": 93.86954471789367, "White blood cell count increased": 7.072907915485345}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1053.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1053.json
index 0fae0cd665f..61ed26c096c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1053.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1053.json
@@ -1 +1 @@
-{"Thrombocytopenia ": 34.07156698320266}
\ No newline at end of file
+{"Confusional state": 5.669563911778029, "Dyskinesia": 28.03310513943156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1054.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1054.json
index 2f085c41b67..abb4eefb625 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1054.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1054.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 16.04641485252656, "Anaemia ": 2.21703539339331, "Aphasia ": 3.804293192407808, "Aplastic anaemia ": 42.15746161684291, "Astrocytoma ": 134.65670303122215, "Astrocytoma malignant ": 857.1310857801292, "Astrocytoma, low grade ": 470.633906066964, "Bone marrow failure ": 22.866841213880523, "Brain oedema ": 9.21045529819666, "Cholestasis ": 3.2985823658421487, "Cytopenia ": 4.797980290171688, "Dermatitis ": 3.529005135167269, "Diabetes insipidus ": 61.41906402176815, "Disease progression ": 16.15421356856522, "Disease recurrence ": 13.053283133201347, "Drug ineffective ": 2.21117844941391, "Drug reaction with eosinophilia and systemic symptoms ": 4.738067750484578, "Drug resistance ": 6.000159797207004, "Drug-induced liver injury ": 2.7360758674578536, "Eastern Cooperative Oncology Group performance status worsened ": 187.3886423931176, "Febrile neutropenia ": 5.276576310830276, "Glioblastoma ": 355.40828063677634, "Glioblastoma multiforme ": 250.3005974242701, "Haematotoxicity ": 55.01334121756218, "Hemiparesis ": 7.634211518217326, "Hepatic failure ": 2.3241201067759727, "Hepatotoxicity ": 3.594665722255572, "Hydrocephalus ": 16.113104648133792, "Hypermutation ": 3989.270212284088, "Hypertransaminasaemia ": 7.499914540658484, "Infection ": 2.4208713724480457, "Jaundice ": 2.7341669762548224, "Leukopenia ": 10.172920643292162, "Liver injury ": 2.825557141379093, "Lymphopenia ": 66.75238665159297, "Malignant neoplasm progression ": 9.587188952169704, "Metastasis ": 11.842009849091328, "Mucosal inflammation ": 3.8913693932643, "Myelodysplastic syndrome ": 32.27090725212073, "Myelosuppression ": 8.396614169605277, "Neoplasm progression ": 10.827016044707758, "Neutropenia ": 9.27793081950365, "Pancytopenia ": 20.55017296647523, "Petechiae ": 3.127501591806748, "Platelet count decreased ": 2.332553895473639, "Platelet transfusion ": 80.54199615150993, "Pneumocystis jirovecii pneumonia ": 17.669069548919932, "Product substitution issue ": 2.75563338050983, "Product use in unapproved indication ": 3.586037708834336, "Recurrent cancer ": 27.349213887157944, "Seizure ": 2.1612008364529225, "Sepsis ": 2.5116269997016007, "Skin reaction ": 3.122019542635341, "Therapeutic product effect incomplete ": 2.276155543131332, "Thrombocytopenia ": 26.29024978772875, "Toxicity to various agents ": 2.4373725895555034, "Treatment failure ": 2.35476778226406, "Tumour pseudoprogression ": 488.9504675403912, "Vanishing bile duct syndrome ": 133.89355413218908}
\ No newline at end of file
+{"Acute myeloid leukaemia": 24.392855630902638, "Agranulocytosis": 32.64999280948443, "Alopecia": 15.24131808896068, "Breast cancer": 2.3841679570405825, "Cardiac failure": 3.7044940923482015, "Diarrhoea": 2.6104567287426024, "Febrile bone marrow aplasia": 47.19696517020128, "Febrile neutropenia": 10.331509711212863, "Flushing": 3.3897819379479044, "Granulocytopenia": 10.186004229820725, "Hepatic function abnormal": 2.8702610770476173, "Interstitial lung disease": 8.553226188585219, "Leukopenia": 15.415440388408028, "Lung disorder": 2.001515387755858, "Malignant neoplasm progression": 2.4246877508444062, "Mucosal inflammation": 10.3136214171609, "Myelosuppression": 17.546431551703954, "Neuropathy peripheral": 2.272561801768008, "Neutropenia": 8.595250315089919, "Neutrophil count decreased": 13.76337197432074, "Oedema": 3.1204572923275715, "Palmar-plantar erythrodysaesthesia syndrome": 4.153081478533539, "Pancytopenia": 3.252733923666057, "Pleural effusion": 2.6175662514993405, "Pneumonitis": 3.392565185806798, "Prostatic specific antigen increased": 8.12737713949123, "Psychological trauma": 231.20972511778865, "Sepsis": 2.791674046342254, "Septic shock": 4.0061911267247465, "Skin exfoliation": 4.51448753622689, "Stomatitis": 9.298416330429918, "White blood cell count decreased": 15.763995605032802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1055.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1055.json
index 8066cea6ef6..321c2a99750 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1055.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1055.json
@@ -1 +1 @@
-{"Anaemia ": 3.950644018200796, "Colitis ": 10.273485339860294, "Dehydration ": 4.06251538057722, "Disease progression ": 7.072765354782429, "Febrile neutropenia ": 29.09691853793297, "Hypertriglyceridaemia ": 37.08302601852363, "Interstitial lung disease ": 5.73365439118869, "Mucosal inflammation ": 15.267585899345825, "Myocardial infarction ": 4.519647519580414, "Neutropenia ": 7.260834303941766, "Neutrophil count decreased ": 6.668299049757854, "Overdose ": 4.736074388706919, "Pneumonia ": 3.099061957816612, "Pneumonitis ": 26.033960533213502, "Stomatitis ": 47.4149557735368, "Thrombocytopenia ": 2.715561165654413, "White blood cell count decreased ": 2.618507955041384}
\ No newline at end of file
+{"Balance disorder": 5.827939587163809, "Fall": 3.620177402181327, "Flushing": 13.435949972517502, "Gait disturbance": 3.11789893368362, "Gastrointestinal disorder": 2.970599946549323, "Memory impairment": 6.514345875131827, "Multiple sclerosis": 46.771396749336944, "Multiple sclerosis relapse": 48.757346912509696, "Muscle spasms": 3.784136065385861, "Muscle spasticity": 27.69113142670508, "Muscular weakness": 2.5932401840977333, "Urinary tract disorder": 83.19803877622537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1056.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1056.json
index 26693758a79..85f71319f64 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1056.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1056.json
@@ -1 +1 @@
-{"Acute kidney injury ": 5.417591513078398, "Alanine aminotransferase increased ": 4.80622794631563, "Aspartate aminotransferase increased ": 2.6535811939677347, "Blood alkaline phosphatase increased ": 2.867471441805755, "Blood bicarbonate decreased ": 55.16388215135517, "Blood creatine phosphokinase increased ": 4.284897958206766, "Blood creatinine increased ": 9.830290059793509, "Blood phosphorus decreased ": 85.43367228710261, "Blood urea increased ": 8.805888805590932, "Bone pain ": 4.274348497211423, "Chronic hepatitis B ": 389.0990288891209, "Chronic kidney disease ": 14.40170331232908, "Drug ineffective ": 2.027207051663556, "Drug resistance ": 12.66793728472928, "Drug-induced liver injury ": 2.310163478860713, "Fanconi syndrome ": 270.4801030760049, "Fanconi syndrome acquired ": 274.5703555001742, "Femur fracture ": 9.745262188288708, "Foetal exposure during pregnancy ": 3.4396858486596025, "Glomerular filtration rate decreased ": 26.25382620265648, "Glycosuria ": 208.0560519742387, "Hepatitis B ": 66.05944286504219, "Hepatitis B DNA increased ": 193.33614043315708, "Hepatitis B reactivation ": 90.9693594286036, "Hypokalaemia ": 4.552127168458829, "Hypophosphataemia ": 127.26828519478757, "Hypophosphataemic osteomalacia ": 846.721781779316, "Immune reconstitution inflammatory syndrome ": 12.867663194107063, "Lactic acidosis ": 3.481036080947576, "Maternal exposure during pregnancy ": 6.16179687642922, "Metabolic acidosis ": 15.265377300721712, "Multiple organ dysfunction syndrome ": 2.5388572546855173, "Nephrogenic diabetes insipidus ": 40.97437493593878, "Nephropathy toxic ": 36.3441495212082, "Osteomalacia ": 99.17814845409876, "Osteopenia ": 5.189291991228509, "Osteoporosis ": 8.634721512900589, "Proteinuria ": 24.1606279256998, "Rebound effect ": 118.93981745434986, "Renal failure ": 3.5900369824311653, "Renal impairment ": 13.01960026871292, "Renal tubular acidosis ": 160.38798791436352, "Renal tubular disorder ": 435.4851892212097, "Renal tubular dysfunction ": 371.5404758912924, "Renal tubular necrosis ": 22.580582914456304, "Treatment noncompliance ": 7.879381013301568, "Tubulointerstitial nephritis ": 5.814511798411333, "Viral load increased ": 51.89174899445597}
\ No newline at end of file
+{"Drug resistance": 254.29199408251824, "Off label use": 23.71985354584165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1057.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1057.json
index 89904063e63..cfbd035548d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1057.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1057.json
@@ -1 +1 @@
-{"Acute graft versus host disease ": 465.04008749833, "Graft versus host disease ": 383.9366784620941, "Mucosal inflammation ": 61.453650752156}
\ No newline at end of file
+{"Abdominal discomfort": 5.104824008091869, "Abdominal distension": 11.73864840142442, "Abdominal pain upper": 2.0946547610980635, "Anxiety": 2.421300950542125, "Apathy": 24.28397027051843, "Back pain": 3.809716613112885, "Balance disorder": 5.59142392900722, "Body temperature increased": 3.919760171494613, "Brain fog": 23.39382677643475, "Compression fracture": 119.30276811746002, "Contusion": 4.402898631708857, "Cough": 2.177310771427423, "Defaecation urgency": 132.1431431313278, "Depressed level of consciousness": 7.268014319753883, "Depression": 2.2393716335766176, "Eructation": 49.58185978617529, "Faeces hard": 249.298143700698, "Fall": 2.472132159958925, "Feeding disorder": 22.883103439136296, "Feeling abnormal": 5.343288421107279, "Flatulence": 24.34308121387681, "Frequent bowel movements": 42.62433073776352, "Gastrointestinal stoma complication": 827.8331164307498, "Gastrointestinal stoma output abnormal": 9535.860229578517, "Hiccups": 52.35140991832138, "Hot flush": 6.604050365706294, "Hypersomnia": 19.015954812781917, "Insomnia": 2.757819922179056, "Intestinal obstruction": 48.92497417169078, "Joint swelling": 4.873595929433718, "Lethargy": 5.576677379220881, "Lumbar vertebral fracture": 131.57213863050626}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1058.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1058.json
index 42da1e37cb7..bfb05a51698 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1058.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1058.json
@@ -1 +1 @@
-{"Nausea ": 3.538019223047813}
\ No newline at end of file
+{"Abdominal pain": 2.595551872054118, "Fall": 4.650179772400432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1059.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1059.json
index ac7029c3bfc..dd3558a2710 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1059.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1059.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 2.27424550433732, "Alopecia ": 5.218457105556481, "Back pain ": 2.35408132758621, "Balance disorder ": 4.788713031039936, "Depressed mood ": 3.6773538294595913, "Fall ": 3.4592618735233875, "Gait disturbance ": 3.353421973267857, "Hepatic enzyme increased ": 3.7271520613998126, "Hypoaesthesia ": 3.1773718405128504, "Memory impairment ": 3.1825561538104483, "Multiple sclerosis ": 35.87273619557571, "Multiple sclerosis relapse ": 74.31171249524328, "Product substitution issue ": 14.914393889373814, "Unevaluable event ": 7.398559640031065, "Urinary tract infection ": 3.0511830535556634}
\ No newline at end of file
+{"Anaemia": 2.7779060769933666, "Cytopenia": 19.392637927828638, "Decreased appetite": 7.484064545801361, "Diarrhoea": 2.654596057841608, "Febrile neutropenia": 2.600021384872554, "Gastrointestinal disorder": 3.325434378516533, "Granulocyte count decreased": 35.40515316876338, "Haemoglobin decreased": 6.601374361586855, "Interstitial lung disease": 5.915587462163558, "Leukopenia": 9.690425588184556, "Malignant neoplasm progression": 2.341822028937473, "Myelosuppression": 98.16820857735608, "Neuropathy peripheral": 6.867848095559886, "Neutropenia": 8.98635464861954, "Neutrophil count decreased": 46.5933605454822, "Platelet count decreased": 24.203811143532118, "Red blood cell count decreased": 15.814446673867652, "Renal impairment": 2.069044047804484, "Thrombocytopenia": 5.370758502293885, "White blood cell count decreased": 32.39378602539339}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/106.json
index b7e7dff2070..3d989fda0d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/106.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 14.712932504523572, "Acanthosis ": 3.689549793530921, "Adjustment disorder with depressed mood ": 3.5715944422090926, "Adverse drug reaction ": 4.650861613686885, "Adverse event ": 3.3333180071501625, "Alanine aminotransferase abnormal ": 2.7256640428272503, "Allergic oedema ": 2.971992854367356, "Allergy to chemicals ": 6.724996482387304, "Alopecia ": 12.54852227596196, "Anaemia of chronic disease ": 3.9938957372538497, "Anal abscess ": 4.494408690296324, "Ankle deformity ": 15.334795269142532, "Ankle operation ": 2.4790450462881704, "Ankylosing spondylitis ": 2.2825634434356075, "Anti-cyclic citrullinated peptide antibody ": 2.753592127250601, "Anti-cyclic citrullinated peptide antibody positive ": 37.69426586849564, "Aortic bruit ": 13.803300886070748, "Appetite disorder ": 3.723861259266066, "Arthritis ": 2.601940896681242, "Arthritis infective ": 7.513313708904587, "Arthrodesis ": 8.73150413354774, "Arthropathy ": 25.81598372032629, "Aspartate aminotransferase ": 2.4766295204909543, "Autoimmune disorder ": 4.1218174645105154, "Back injury ": 5.941411951629891, "Basal cell carcinoma ": 2.1385786500683297, "Benign neoplasm ": 4.60588286202586, "Bladder operation ": 2.812469797532208, "Blister ": 5.228731849232858, "Blood cholesterol increased ": 7.327596191638046, "Blood immunoglobulin A decreased ": 2.179550263868893, "Blood immunoglobulin M increased ": 2.2861965629979397, "Blood iron abnormal ": 127.69965101505848, "Blood magnesium increased ": 9.490800288893864, "Blood parathyroid hormone decreased ": 7.5213671382287615, "Blood pressure diastolic abnormal ": 2.4242869596020173, "Blood pressure systolic abnormal ": 2.3735426771780355, "Bloody discharge ": 3.166956466825836, "Bone cyst ": 23.247899823677518, "Bone deformity ": 2.6304053565746464, "Bone erosion ": 29.95929272242476, "Bone graft ": 9.212926098114693, "Bone swelling ": 11.271256090841714, "Breast cancer stage II ": 2.031472754369356, "Breast cancer stage III ": 3.725126325368865, "Breast prosthesis user ": 34.65529341395296, "Bunion operation ": 55.15942871392636, "Bursitis ": 4.767716444208414, "Bursitis infective ": 6.5922797978762935, "C-reactive protein ": 11.950270559436058, "C-reactive protein abnormal ": 19.30095736263544, "C-reactive protein decreased ": 2.989895740836226, "C-reactive protein increased ": 3.0563512391167804, "Carbon dioxide abnormal ": 15.242397456482294, "Carbon dioxide decreased ": 4.879140844356236, "Chondropathy ": 4.359100504768151, "Coeliac disease ": 2.782860756321908, "Colitis microscopic ": 3.3629362434143157, "Condition aggravated ": 3.77624779827956, "Congenital anomaly ": 11.893907068626804, "Contraindicated product administered ": 32.50095198601979, "Contraindicated product prescribed ": 3.093960960985429, "Contraindication to vaccination ": 4.170106012900478, "Contrast media allergy ": 2.624520251869501, "Contusion ": 3.29227130298331, "Crepitations ": 2.949842769296088, "Cytology abnormal ": 9.794604072561938, "Deafness transitory ": 11.25520099102776, "Deep vein thrombosis postoperative ": 14.772646574690947, "Deformity ": 4.822640778587149, "Dermatitis psoriasiform ": 3.6592529912643257, "Discomfort ": 12.537173983712538, "Disease susceptibility ": 4.002971819270885, "Dislocation of vertebra ": 2.1452598055171865, "Drug hypersensitivity ": 6.205757257189551, "Drug ineffective ": 3.796937229504866, "Drug intolerance ": 14.61619281106328, "Drug tolerance ": 2.11645187883455, "Drug tolerance decreased ": 22.93940708484903, "Duodenal ulcer perforation ": 34.065418763154184, "Dysphoria ": 2.379511087341074, "Ear pain ": 5.567050791520222, "Elbow deformity ": 9.311176102348565, "Elbow operation ": 6.080852419362097, "Encephalitis brain stem ": 3.7569711732721247, "Endocrine ophthalmopathy ": 6.369846722976291, "Epigastric discomfort ": 2.0426927597005764, "Exostosis ": 13.483575248992612, "Extremity contracture ": 4.12261672161392, "Eyelid disorder ": 2.7803840561812248, "Facet joint syndrome ": 7.414104810804019, "Fibromyalgia ": 4.219813130426774, "Fine motor skill dysfunction ": 5.173450313585176, "Finger deformity ": 11.55157223123226, "Folliculitis ": 13.90153789143132, "Foot deformity ": 13.215457919014629, "Foot operation ": 7.043414607298327, "Functional gastrointestinal disorder ": 2.3804125527506703, "Gait inability ": 2.2396155511784417, "Gastroenteritis salmonella ": 2.3186112870267075, "Gastrointestinal disorder ": 4.319061886164499, "Gastrointestinal toxicity ": 11.267506862881076, "General physical health deterioration ": 3.724061040242344, "Glossodynia ": 47.29144898429404, "Granuloma skin ": 9.644300144015356, "Granulomatous dermatitis ": 4.924562288271879, "Grip strength decreased ": 3.094889078082489, "Haemodilution ": 15.3284034178499, "Haemorrhagic diathesis ": 4.07947572293086, "Hand deformity ": 57.71582471304931, "Helicobacter infection ": 31.054248932287692, "Hepatic enzyme increased ": 8.841971590008157, "Hepatic fibrosis ": 2.2515180600756315, "Hepatic haematoma ": 6.094181489152541, "Hepatic steatosis ": 2.3329643479107456, "Hepatitis B core antibody positive ": 4.632450185080048, "Hepatotoxicity ": 2.7113613139895683, "Hip arthroplasty ": 16.904942103738954, "Hip deformity ": 4.3920892718757925, "Histiocytosis ": 11.067650723711097, "Hunger ": 4.2383840352292, "Hypercholesterolaemia ": 4.321248847843233, "Hypermobility syndrome ": 6.647557261094192, "Hypersensitivity ": 4.387726764830991, "Ill-defined disorder ": 5.669340981066956, "Immobile ": 4.2106916915654615, "Impaired healing ": 9.776260801158914, "Infection ": 4.30173791377368, "Infusion related reaction ": 14.73064050774406, "Intentional product use issue ": 2.847906255774537, "Interferon gamma release assay positive ": 16.758174057839074, "Intervertebral disc compression ": 14.617737341870194, "Intervertebral disc space narrowing ": 20.58020249263744, "Intestinal polyp ": 3.0837720061716, "Investigation abnormal ": 5.911467402154835, "Irritable bowel syndrome ": 7.768570336147479, "Joint ankylosis ": 8.046287844131554, "Joint arthroplasty ": 4.161442644088457, "Joint dislocation ": 5.753712258838939, "Joint injury ": 4.748705729083529, "Joint laxity ": 5.151766884011396, "Joint lock ": 3.154680827114403, "Joint range of motion decreased ": 3.7405211176097497, "Joint space narrowing ": 3.845334368217507, "Joint stiffness ": 6.916842347449433, "Joint surgery ": 11.199576096141415, "Joint swelling ": 14.254563836023484, "Keratitis ": 2.0890813479578694, "Kidney infection ": 3.107948667693437, "Knee arthroplasty ": 18.66581368085681, "Labile blood pressure ": 2.131296654253137, "Laryngeal disorder ": 12.69420637316792, "Laryngitis ": 2.9137284949269024, "Limb deformity ": 8.839749034402201, "Limb operation ": 2.578357070322252, "Lip ulceration ": 3.502370454611716, "Live birth ": 6.834261988394675, "Liver function test increased ": 2.9102686130140705, "Liver injury ": 6.35759750154798, "Localised infection ": 2.3168242017485885, "Loose body in joint ": 4.246605494391295, "Loss of employment ": 6.622548449023761, "Loss of personal independence in daily activities ": 3.597968762727217, "Lower limb fracture ": 2.5712653021751777, "Lower respiratory tract infection ": 8.20569673439919, "Lupus vulgaris ": 2.104030994476698, "Lupus-like syndrome ": 2.16926106935813, "Lymphocyte count increased ": 2.9050355953365687, "Maculopathy ": 2.0988054650031627, "Maternal exposure before pregnancy ": 2.7943857226769566, "Maternal exposure during pregnancy ": 10.60486212078613, "Mean cell haemoglobin increased ": 6.95476286059655, "Medical device implantation ": 2.991779229381196, "Microcytic anaemia ": 2.0069486068144857, "Mobility decreased ": 2.566890644372059, "Morphoea ": 2.9813486577318904, "Multiple allergies ": 2.307347809628296, "Muscle injury ": 11.258973495805348, "Muscle spasticity ": 21.042189494675814, "Musculoskeletal disorder ": 5.053214500409497, "Musculoskeletal pain ": 4.061352684228294, "Musculoskeletal stiffness ": 6.168357153468685, "Mycobacterium tuberculosis complex test positive ": 4.447792284993893, "Nail disorder ": 2.6396625440550934, "Nail operation ": 7.458853867128867, "Nasal ulcer ": 6.783110762184133, "Neck deformity ": 17.007863968389056, "Nephrolithiasis ": 2.431805185606731, "Nerve injury ": 3.5035650715671265, "Night sweats ": 4.958419837141051, "Non-Hodgkin's lymphoma ": 5.497199970593192, "Ocular toxicity ": 3.661620326929036, "Onycholysis ": 3.859474178586268, "Osteoarthritis ": 4.000949170567793, "Osteolysis ": 5.403231900069628, "Osteosclerosis ": 4.079493885432548, "Ovarian neoplasm ": 3.824492475410161, "Pain ": 3.2036804497545424, "Panniculitis ": 2.265618622220262, "Pemphigus ": 98.96507651564156, "Pericarditis ": 9.89118039729899, "Peripheral swelling ": 2.933660418066702, "Pleural fibrosis ": 5.866102604500076, "Pleural thickening ": 4.670280547142492, "Pneumonia cryptococcal ": 2.830334034410101, "Pneumonia viral ": 2.528507992149643, "Presbyacusis ": 9.149546053071983, "Prescribed underdose ": 3.5587368366656547, "Product label confusion ": 9.402989570418708, "Product use issue ": 7.411772078949007, "Pruritus allergic ": 2.804497435681925, "Psoriatic arthropathy ": 9.548644909845526, "Pulmonary congestion ": 3.164545355822763, "Pulmonary fibrosis ": 2.688814806170543, "Pulmonary mass ": 2.4991775845595097, "Pulmonary toxicity ": 8.333499679342365, "Pustular psoriasis ": 2.681373680423466, "Red blood cell sedimentation rate abnormal ": 21.83408710047699, "Red blood cell sedimentation rate increased ": 5.355280711869139, "Red cell distribution width increased ": 2.0390654708420626, "Respiratory disorder ": 6.309106340480904, "Respiratory tract congestion ": 6.739448029026648, "Respiratory tract infection viral ": 2.4298096508246583, "Rheumatic fever ": 31.35657492616648, "Rheumatoid arthritis ": 26.075039105980768, "Rheumatoid factor increased ": 2.882240675672327, "Rheumatoid factor negative ": 54.05435480938698, "Rheumatoid factor positive ": 57.678731259422975, "Rheumatoid lung ": 7.327843084994484, "Rheumatoid nodule ": 34.11991791423619, "Sciatica ": 2.775598812585476, "Sensitivity to weather change ": 2.342490154516256, "Seronegative arthritis ": 7.056097733713079, "Shoulder arthroplasty ": 4.2930570824520204, "Sinusitis ": 5.587221436968477, "Sjogren's syndrome ": 4.2873256399977535, "Skin ulcer ": 2.360997450507514, "Skin warm ": 2.835876712100337, "Sleep disorder due to general medical condition, insomnia type ": 6.351568711870869, "Soft tissue disorder ": 8.016844953796777, "Soft tissue swelling ": 5.49261517478714, "Stomatitis ": 2.098328157452735, "Stress at work ": 4.354303970139391, "Surgical failure ": 4.603269345261382, "Swelling ": 10.424636986412722, "Swollen joint count increased ": 49.96763288366297, "Synovial cyst ": 3.8386537542175647, "Synovial disorder ": 2.495526998722089, "Synovitis ": 41.80207348107168, "Systemic lupus erythematosus ": 50.23340268059884, "Systemic lupus erythematosus rash ": 47.50591294671756, "Tenosynovitis ": 7.702459631349291, "Therapeutic product effect decreased ": 11.316951978945765, "Therapeutic product effect incomplete ": 3.1106026350342577, "Therapy non-responder ": 2.251893454637893, "Thyroid neoplasm ": 9.98092848928448, "Tonsillar disorder ": 2.312648863525, "Tooth disorder ": 3.683164970564284, "Tooth infection ": 8.292598575101, "Transplant dysfunction ": 2.799759743348389, "Treatment failure ": 12.305580702433332, "Tuberculin test positive ": 15.27054461304094, "Type 2 diabetes mellitus ": 4.928721738995066, "Vaginal haematoma ": 32.71066964142666, "Viral upper respiratory tract infection ": 2.532275251851558, "White blood cell count abnormal ": 14.849201187849102, "Wound ": 42.467593812004566, "Wrist deformity ": 7.603789562738561, "Wrist surgery ": 7.659929583161888, "X-ray abnormal ": 6.262361852890722}
\ No newline at end of file
+{"Acute kidney injury": 14.52064540017142, "Acute respiratory distress syndrome": 2.472991548016431, "Ageusia": 2.181154585719559, "Agranulocytosis": 2.004319071571178, "Aneurysm": 11.412858478747223, "Angioedema": 6.318404623719389, "Anuria": 6.311208650492318, "Aplasia pure red cell": 3.8706485737598055, "Aspiration": 8.440067063008858, "Bacteraemia": 4.905155051381043, "Blood creatine phosphokinase increased": 4.43309110819312, "Blood creatinine increased": 4.450656836076559, "Blood potassium increased": 2.9806674156757595, "Blood pressure abnormal": 3.124653917256459, "Blood pressure fluctuation": 4.204710477006564, "Blood pressure inadequately controlled": 4.671685687153838, "Blood pressure increased": 4.769438576719344, "Blood urea increased": 2.3481193306490296, "Blood uric acid increased": 4.358617444526064, "Bradycardia": 4.701570931250727, "Bundle branch block left": 8.415018469696934, "Cardio-respiratory arrest": 3.5116075199547474, "Cardiogenic shock": 2.2873306719462456, "Cholestasis": 2.178512795890986, "Coma": 2.5074433303439903, "Cutaneous vasculitis": 11.179387334071526, "Dehydration": 3.039183739363568, "Dermatitis exfoliative generalised": 5.290564489023077, "Dyspepsia": 2.1767888702875564, "Eczema": 3.733806859456663, "Eosinophilia": 5.603570250181797, "Erectile dysfunction": 3.526972715731545, "Erysipelas": 6.778911350005282, "Face oedema": 2.664268242226385, "Fall": 2.918674806346199, "Gamma-glutamyltransferase increased": 3.5162151285545478, "Hepatic cytolysis": 7.710822488735213, "Hepatitis": 2.614531253140855, "Hepatitis cholestatic": 3.6148948053102288, "Hyperglycaemia": 2.458200316237769, "Hyperkalaemia": 30.76454710029234, "Hypertension": 3.3278259770567447, "Hypertensive crisis": 5.691066606938431, "Hyponatraemia": 10.221168143099996, "Hypotension": 5.173437850702689, "Inappropriate antidiuretic hormone secretion": 5.4333392555809095, "Jaundice": 2.692694845794366, "Lactic acidosis": 8.857360107106622, "Laryngeal oedema": 2.3563820434167293, "Medication error": 3.610546537199228, "Metabolic acidosis": 3.200443283277981, "Mitral valve incompetence": 5.841482451100019, "Multiple organ dysfunction syndrome": 2.071835076797017, "Musculoskeletal chest pain": 5.623627501616175, "Oedema peripheral": 2.092850980641216, "Orthostatic hypotension": 18.56403432181273, "Pancreatitis acute": 3.834222051394935, "Pancytopenia": 2.5661465954962472, "Photosensitivity reaction": 2.9198133270704365, "Pregnancy": 3.8475409051214657, "Product administration error": 2.720537302767459, "Product availability issue": 5.2569617447089545, "Pulmonary arterial hypertension": 4.593257087603842, "Rash vesicular": 2.316157012955151, "Renal failure": 4.175314225542029, "Renal tubular necrosis": 5.4774667936326, "Rhabdomyolysis": 3.719814650151701, "Shock": 4.864251415765066, "Subarachnoid haemorrhage": 2.666400284847539, "Therapy non-responder": 2.702710992373264, "Tongue oedema": 2.743003058774251, "Toxic skin eruption": 2.158757683751209, "Tubulointerstitial nephritis": 4.4593622910221145, "Vasculitis": 3.717432192140981, "Wrong patient received product": 10.504769856100603, "Wrong product administered": 2.118230643852501, "Wrong technique in product usage process": 2.282583730077586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1060.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1060.json
index 1ff4cdd95cc..139d974181e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1060.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1060.json
@@ -1 +1 @@
-{"Back pain ": 3.2535292471658583, "Bone pain ": 4.1287137660365465, "Calciphylaxis ": 159.30080992833138, "Fall ": 5.765573187401218, "Femur fracture ": 16.10478800098519, "Hip fracture ": 15.484716274988267, "Hospitalisation ": 2.0386633959000635, "Hypercalcaemia ": 76.67013068304536, "Muscle spasms ": 2.469262203061878, "Nephrolithiasis ": 6.1441501362115165, "Renal impairment ": 2.354725013778273, "Skin necrosis ": 19.31323140631608, "Spinal compression fracture ": 18.35043349921976, "Spinal fracture ": 13.013928960845346, "Upper limb fracture ": 19.51463055554854}
\ No newline at end of file
+{"Angioedema": 4.852526923056708, "Blood creatinine increased": 9.11414697954562, "Blood potassium increased": 26.68296229833696, "Blood pressure inadequately controlled": 143.43369787291007, "Blood pressure increased": 8.850686979422518, "Cerebrovascular accident": 2.6342586219275974, "Drug interaction": 2.1225108539429067, "Hyperkalaemia": 6.718051989338982, "Hypertension": 4.070012386267104, "Palpitations": 2.2555678102262497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1061.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1061.json
index fbbf368b05a..304a7ce37e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1061.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1061.json
@@ -1 +1 @@
-{"Back pain ": 4.502696978429284, "Bone pain ": 6.888177846802693, "Device malfunction ": 17.42239485942071, "Dizziness ": 2.975380818238293, "Injection site bruising ": 42.52910538142604, "Injection site erythema ": 4.430756947462962, "Injection site haemorrhage ": 26.57497786214627, "Muscle spasms ": 3.495796094787281, "Nausea ": 2.087142972732305, "Pain in extremity ": 2.738348488732794, "Palpitations ": 3.018722676984012, "Product dose omission issue ": 5.198305610758029, "Therapy interrupted ": 62.73146371117658, "Wrong technique in device usage process ": 44.20027338226655}
\ No newline at end of file
+{"Anaemia": 20.976499490462054, "Blood creatinine increased": 20.323346852892215, "Drug interaction": 15.697916934734002, "Pruritus": 2.5581282005215877, "Rash": 5.457817515817974, "Thrombocytopenia": 4.147000690645847}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1062.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1062.json
index 43fa818ce3a..49c866b3fae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1062.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1062.json
@@ -1 +1 @@
-{"Accidental exposure to product ": 12.133928462726663, "Acne ": 9.482122962005262, "Acute myocardial infarction ": 17.65475484534197, "Aggression ": 4.5183831739044376, "Anger ": 5.4076833385033, "Angina pectoris ": 2.9020354193847595, "Aortic aneurysm ": 18.258745645855708, "Arteriosclerosis ": 10.723714771519749, "Atrial fibrillation ": 2.0124080333086325, "Blood testosterone decreased ": 86.29151750289886, "Blood testosterone increased ": 402.4808588251767, "Bone disorder ": 7.145259602703311, "Breast cancer ": 3.90925065961056, "Breast cancer metastatic ": 8.942166329506405, "Cardiac death ": 99.10206935253902, "Cardiac failure congestive ": 2.182295636042926, "Cardiomyopathy ": 7.394616815611124, "Cerebrovascular accident ": 4.358027315645759, "Cholestasis ": 3.115088246584666, "Coronary artery disease ": 11.698049165440857, "Coronary artery occlusion ": 6.878589948916703, "Deep vein thrombosis ": 15.49091109553344, "Device dislocation ": 34.210530559679896, "Device malfunction ": 6.05952459091586, "Drug abuse ": 12.984058523005102, "Drug-induced liver injury ": 2.5714357885909904, "Dyslipidaemia ": 9.428058377200806, "Endometrial cancer ": 45.82588833505356, "Erectile dysfunction ": 5.861588361794704, "Gynaecomastia ": 7.1351328836930366, "Hair growth abnormal ": 28.50880331471912, "Idiopathic intracranial hypertension ": 65.82142776256607, "Intentional product misuse ": 3.0541380412068246, "Invasive ductal breast carcinoma ": 17.47619105370686, "Jaundice ": 3.0896299929626605, "Left ventricular hypertrophy ": 46.62225786585368, "Libido decreased ": 7.07597971587408, "Mesenteric vein thrombosis ": 50.04406637958645, "Muscle mass ": 195.39051143952344, "Myocardial fibrosis ": 92.16453514520332, "Myocardial infarction ": 4.311761855990994, "Obstructive sleep apnoea syndrome ": 27.36125663288645, "Oestradiol increased ": 182.0430068416356, "Off label use ": 2.642928006776543, "Osteonecrosis ": 3.1980220199220595, "Papilloedema ": 18.204226209297303, "Polycythaemia ": 194.5021391228964, "Portal vein thrombosis ": 23.015678258440865, "Precocious puberty ": 180.70576479241248, "Prescription drug used without a prescription ": 22.69348618358044, "Product quality issue ": 13.9082561483666, "Product use in unapproved indication ": 2.8725928222521997, "Product use issue ": 7.260814834947145, "Prostate cancer ": 6.712579923483899, "Prostatic specific antigen increased ": 10.009669084425653, "Pulmonary embolism ": 8.985918267734501, "Self-medication ": 59.12310105212452, "Testicular atrophy ": 131.1330952288465, "Therapeutic product effect decreased ": 2.223839866377145, "Thrombosis ": 2.770689065908854, "Transgender hormonal therapy ": 3987.402969464821, "Virilism ": 929.6762637530966}
\ No newline at end of file
+{"Stevens-Johnson syndrome": 235.45859548184885}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1063.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1063.json
index a5ee27d83c3..757a2f581ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1063.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1063.json
@@ -1 +1 @@
-{"Bone pain ": 27.846789229238368, "Drug ineffective ": 7.129563425841416, "Erythema ": 6.3232184249857255}
\ No newline at end of file
+{"Drug resistance": 148.29231174476035, "Therapeutic response decreased": 129.52114819956003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1064.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1064.json
index 1543e106a29..812081ca49c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1064.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1064.json
@@ -1 +1 @@
-{"Product use in unapproved indication ": 20.18888135059103}
\ No newline at end of file
+{"Acute kidney injury": 3.794996012364297, "Angioedema": 7.017530788545577, "Asthma": 2.969908944251255, "Atrioventricular block complete": 5.830511208547697, "Autonomic neuropathy": 85.42130020171288, "Blood creatine phosphokinase increased": 3.496464806514477, "Blood creatinine increased": 2.3743380964573357, "Blood pressure abnormal": 4.590611781376902, "Blood pressure decreased": 3.355362847262481, "Blood pressure fluctuation": 3.6105456277226993, "Blood pressure inadequately controlled": 42.25598979425666, "Blood pressure increased": 3.3168304021918025, "Blood pressure systolic increased": 3.729874266038971, "Blood urea increased": 3.140265540239677, "Bradycardia": 4.090832288773228, "Cardio-respiratory arrest": 4.826456496855538, "Chest discomfort": 3.261743866805755, "Clostridium difficile infection": 6.492767959112053, "Clumsiness": 44.01255712891343, "Cognitive disorder": 3.492785374209239, "Cough": 2.746835024175105, "Cranial nerve disorder": 95.0725410915532, "Drug interaction": 2.823500108073976, "Drug level increased": 2.8350645496234783, "Drug reaction with eosinophilia and systemic symptoms": 2.4105719907855825, "Electrocardiogram abnormal": 4.918461170090918, "Encephalopathy": 3.8846470810827474, "Forced expiratory flow decreased": 2804.388150094649, "Forced vital capacity decreased": 311.63286284412646, "Full blood count abnormal": 5.310903785908307, "Giant cell arteritis": 34.0285107602632, "Heart rate decreased": 5.281758681616276, "Hypercalcaemia": 8.75568038213015, "Hyperkalaemia": 10.28591351165527, "Hypertensive crisis": 5.356696146564699, "Hypokalaemia": 2.273463676710508, "Hyponatraemia": 4.158363038635899, "Hypotension": 3.0927404476302844, "Illness": 2.153865259770189, "Jaw disorder": 47.529180325284045, "Left ventricular hypertrophy": 12.13198423660111, "Loss of personal independence in daily activities": 4.800037831736784, "Meningitis aseptic": 12.6570295587455, "Mononeuropathy multiplex": 120.48405403877672, "Myelitis": 29.142288020288525, "Nasopharyngitis": 4.014368683866509, "Oedema peripheral": 3.000349987672477, "Oligohydramnios": 27.02468754792876, "Oliguria": 5.370400027937494, "Optic neuropathy": 42.39028228996898, "Oral discomfort": 5.600585268935812, "Orthostatic hypotension": 7.026435944865429, "Peripheral sensorimotor neuropathy": 69.99693825383892, "Peripheral sensory neuropathy": 15.417019349574757, "Product substitution issue": 20.64133703091313, "Product use issue": 3.771594390572568, "Prolonged expiration": 84.50497864567333, "Proteinuria": 2.89361043441058, "Pyelonephritis": 6.255679723179492, "Red blood cell sedimentation rate increased": 9.898958802959395, "Rhabdomyolysis": 2.479783272090896, "SARS-CoV-2 test positive": 3.7698750474433584, "Schizophrenia": 6.0018915112044855, "Shock": 3.060508605316859, "Sjogren's syndrome": 26.32475250699679, "Sleep disorder due to a general medical condition": 19.626837093032712, "Small fibre neuropathy": 52.36215712988933, "Therapeutic product effect incomplete": 5.949670181101318, "Thirst": 2.6013816464191817, "Toxic epidermal necrolysis": 2.0374826664606847, "Toxicity to various agents": 2.565865072581975, "Wheezing": 5.55734223598461}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1065.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1065.json
index 4f47e42f72e..6b5c7d2a7d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1065.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1065.json
@@ -1 +1 @@
-{"Asthma ": 32.77069085038518}
\ No newline at end of file
+{"Accidental overdose": 2.021944068519444, "Acute myeloid leukaemia": 4.697469622613545, "Adverse event": 5.159673582685695, "Agranulocytosis": 6.890720876523194, "Anaemia": 2.993281424593362, "Aphasia": 2.679084608244679, "Aplastic anaemia": 15.6668334258515, "Bone marrow failure": 75.58261547778442, "Brain oedema": 14.227845757049147, "Cerebral haemorrhage": 3.0396994652250915, "Cholestasis": 10.19912620418355, "Congenital aplasia": 35.24216535614194, "Cytomegalovirus infection": 3.53531543677993, "Cytopenia": 6.188900948772196, "Death": 2.3222845907838314, "Disease progression": 14.26524598055019, "Disseminated intravascular coagulation": 4.194103887785389, "Drug eruption": 4.608319039707278, "Dysphagia": 3.6091554354653006, "Eastern Cooperative Oncology Group performance status worsened": 65.30374806141688, "Eosinophilia": 2.084203745807542, "Epilepsy": 2.5343123483670507, "Erythema multiforme": 2.18331725783742, "Febrile bone marrow aplasia": 61.711446118932976, "Febrile neutropenia": 4.228854622574868, "Gamma-glutamyltransferase increased": 3.189726350476666, "Gingival bleeding": 2.848373774378412, "Glioblastoma": 117.97095157262052, "Glioblastoma multiforme": 115.2803270972064, "Haematotoxicity": 6.993518151542569, "Haemolytic anaemia": 3.464307995711492, "Haemorrhage intracranial": 2.6301496434181058, "Hemiparesis": 4.2270607926352834, "Hemiplegia": 7.007870727675664, "Hepatic cytolysis": 11.070975910716482, "Hepatic function abnormal": 4.41479338813716, "Hepatocellular injury": 6.298118991076426, "Hepatotoxicity": 3.1233405925009, "Interstitial lung disease": 2.0377330514662835, "Intracranial pressure increased": 8.988180294232402, "Intracranial tumour haemorrhage": 190.7489374680354, "Jaundice": 2.0581519060457216, "Leukoencephalopathy": 12.398851522272532, "Leukopenia": 13.303415553079107, "Liver disorder": 2.0097685927862594, "Liver injury": 2.0615874713278037, "Lymphocyte count decreased": 23.094458699195787, "Lymphopenia": 16.674801654465757, "Malignant neoplasm progression": 3.857710699635272, "Mucosal inflammation": 2.4011345527312358, "Multiple organ dysfunction syndrome": 2.082849472234703, "Myelodysplastic syndrome": 6.27015846392321, "Myelosuppression": 8.261112096626821, "Neoplasm progression": 3.231750117357893, "Neutropenia": 8.200406187995402, "Neutrophil count decreased": 3.684202822636038, "Pancytopenia": 30.67959178025011, "Petechiae": 4.815179466232132, "Platelet count decreased": 6.737346898345562, "Platelet transfusion": 56.856190435632094, "Pneumocystis jirovecii infection": 54.99866947203114, "Pneumocystis jirovecii pneumonia": 30.49218608333081, "Pneumonia": 2.4978529532977016, "Pneumonia aspiration": 2.516245893760322, "Pulmonary embolism": 3.933902126670397, "Purpura": 4.5105509531288135, "Rash maculo-papular": 2.786022985223884, "Recurrent cancer": 24.547397118912546, "Seizure": 2.105077562087981, "Sepsis": 6.073810292992525, "Septic shock": 2.19057012296935, "Stevens-Johnson syndrome": 7.507667580523036, "Surgery": 2.4341280729344525, "Thrombocytopenia": 22.970093691845168, "Toxic epidermal necrolysis": 4.94899784780584, "Toxic skin eruption": 5.325183131055749, "White blood cell count decreased": 4.697841444563848}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1066.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1066.json
index d40549a8033..e6a6d365796 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1066.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1066.json
@@ -1 +1 @@
-{"Acute lymphocytic leukaemia ": 15.812596111587196, "Acute myeloid leukaemia ": 5.498676222119293, "Acute myocardial infarction ": 2.51947590093894, "Atelectasis ": 5.550066240676565, "Bone disorder ": 4.40870021513675, "Bone lesion ": 21.1461499036955, "Bradycardia ": 4.76426431671323, "Cardiac failure ": 2.8866464699666, "Constipation ": 4.409454140698935, "Cutaneous vasculitis ": 5.137814944953071, "Cytopenia ": 3.3614996845067195, "Death ": 3.432036286069746, "Deep vein thrombosis ": 12.461071063351248, "Disease progression ": 5.423874211474828, "Disorientation ": 2.00625300028967, "Drug intolerance ": 2.168788886952251, "Drug reaction with eosinophilia and systemic symptoms ": 5.232508679075661, "Dysaesthesia ": 4.974378184157472, "Embolism ": 9.526398187641204, "Febrile neutropenia ": 3.443644831636957, "Infection ": 2.6350909874578123, "Myelodysplastic syndrome ": 6.728775349883188, "Neuropathy peripheral ": 36.88539939712409, "Neurotoxicity ": 4.854351083876428, "Neutropenia ": 2.935765394524316, "Oedema ": 2.486531273173087, "Oedema peripheral ": 3.145178411541293, "Orthostatic hypotension ": 3.313992552935185, "Osteonecrosis of jaw ": 12.31537943769507, "Pancytopenia ": 4.191613805125339, "Paraesthesia ": 2.4860527681080287, "Peripheral motor neuropathy ": 68.0896975870547, "Peripheral sensory neuropathy ": 86.03693107542922, "Plasma cell myeloma ": 49.61178118538482, "Plasma cell myeloma recurrent ": 46.55714078620445, "Plasmacytoma ": 74.41602336223518, "Pneumonia ": 2.0727183197664885, "Pneumonitis ": 2.956133445462064, "Polyneuropathy ": 23.35385164384917, "Pulmonary embolism ": 8.641650065482954, "Pulmonary hypertension ": 2.786863653378804, "Rash maculo-papular ": 3.2109750819015503, "Renal impairment ": 2.2589405225942327, "Sepsis ": 4.265431141318596, "Septic shock ": 2.9667337358143904, "Sinus bradycardia ": 4.420869636439437, "Therapy non-responder ": 9.953902823222815, "Toxic skin eruption ": 3.851538552788668, "Transient ischaemic attack ": 2.8797802067650737, "Tumour lysis syndrome ": 8.188848339258541, "Type 2 lepra reaction ": 200.82207246801983, "Varicella zoster virus infection ": 25.852618001457504, "Venous thrombosis limb ": 11.007824549815108}
\ No newline at end of file
+{"Thrombocytopenia": 34.068362137670974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1067.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1067.json
index beb358bff02..ab9952931df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1067.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1067.json
@@ -1 +1 @@
-{"Acute lymphocytic leukaemia ": 200.72756871358172, "Decreased appetite ": 4.975512483857825, "Febrile neutropenia ": 17.563989664438253, "Leukopenia ": 10.748193567293193, "Mucosal inflammation ": 27.58822158590593, "Myelosuppression ": 6.927597858062939, "Stomatitis ": 13.94546001504778, "Vomiting ": 2.306500115656245}
\ No newline at end of file
+{"Acute myeloid leukaemia": 16.04641485252656, "Anaemia": 2.21703539339331, "Aphasia": 3.803726376746415, "Aplastic anaemia": 42.15746161684291, "Astrocytoma": 134.65670303122215, "Astrocytoma malignant": 857.1310857801292, "Astrocytoma, low grade": 470.633906066964, "Bone marrow failure": 22.866841213880523, "Brain oedema": 9.21045529819666, "Cholestasis": 3.2985823658421487, "Cytopenia": 4.79416271297974, "Dermatitis": 3.528543307937692, "Diabetes insipidus": 61.41906402176815, "Disease progression": 16.15421356856522, "Disease recurrence": 13.053283133201347, "Drug ineffective": 2.211162095761864, "Drug reaction with eosinophilia and systemic symptoms": 4.737676161759718, "Drug resistance": 6.000159797207004, "Drug-induced liver injury": 2.7359090555583907, "Eastern Cooperative Oncology Group performance status worsened": 187.3886423931176, "Febrile neutropenia": 5.276576310830276, "Glioblastoma": 355.40828063677634, "Glioblastoma multiforme": 250.3005974242701, "Haematotoxicity": 55.01334121756218, "Hemiparesis": 7.633248053251657, "Hepatic failure": 2.3241201067759727, "Hepatotoxicity": 3.594665722255572, "Hydrocephalus": 16.113104648133792, "Hypermutation": 3989.270212284088, "Hypertransaminasaemia": 7.499914540658484, "Infection": 2.4208713724480457, "Jaundice": 2.7341669762548224, "Leukopenia": 10.17163516166689, "Liver injury": 2.825557141379093, "Lymphopenia": 66.75238665159297, "Malignant neoplasm progression": 9.587188952169704, "Metastasis": 11.842009849091328, "Mucosal inflammation": 3.8913693932643, "Myelodysplastic syndrome": 32.27090725212073, "Myelosuppression": 8.396614169605277, "Neoplasm progression": 10.827016044707758, "Neutropenia": 9.277530940996504, "Pancytopenia": 20.55017296647523, "Petechiae": 3.127501591806748, "Platelet count decreased": 2.332553895473639, "Platelet transfusion": 80.54199615150993, "Pneumocystis jirovecii pneumonia": 17.669069548919932, "Product substitution issue": 2.75563338050983, "Product use in unapproved indication": 3.5859257910295024, "Recurrent cancer": 27.349213887157944, "Seizure": 2.1609611552650967, "Sepsis": 2.5116269997016007, "Skin reaction": 3.122019542635341, "Therapeutic product effect incomplete": 2.276155543131332, "Thrombocytopenia": 26.28776013175121, "Toxicity to various agents": 2.4373725895555034, "Treatment failure": 2.35476778226406, "Tumour pseudoprogression": 488.9504675403912, "Vanishing bile duct syndrome": 133.89355413218908}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1068.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1068.json
index 9e26dfeeb6e..2c6d567f34f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1068.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1068.json
@@ -1 +1 @@
-{}
\ No newline at end of file
+{"Anaemia": 3.950644018200796, "Colitis": 10.273485339860294, "Dehydration": 4.062298553578651, "Disease progression": 7.072765354782429, "Febrile neutropenia": 29.09691853793297, "Hypertriglyceridaemia": 37.08302601852363, "Interstitial lung disease": 5.73365439118869, "Mucosal inflammation": 15.267585899345825, "Myocardial infarction": 4.519647519580414, "Neutropenia": 7.260522026211707, "Neutrophil count decreased": 6.668299049757854, "Overdose": 4.736074388706919, "Pneumonia": 3.099061957816612, "Pneumonitis": 26.033960533213502, "Stomatitis": 47.4149557735368, "Thrombocytopenia": 2.715305727058652, "White blood cell count decreased": 2.618507955041384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1069.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1069.json
index 7d2295c11c2..2c6d52a1e51 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1069.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1069.json
@@ -1 +1 @@
-{"Acute graft versus host disease ": 40.98962384468704, "Acute graft versus host disease in intestine ": 162.54282149464166, "Acute graft versus host disease in skin ": 191.7586418440809, "Acute promyelocytic leukaemia ": 80.76217224837043, "Acute respiratory distress syndrome ": 17.10351741163306, "Adenovirus infection ": 53.87190121599772, "Anaemia ": 4.726986018840199, "Aplastic anaemia ": 16.247896771933043, "Chronic graft versus host disease ": 39.84050064061359, "Chronic graft versus host disease in skin ": 192.51735717586604, "Cystitis haemorrhagic ": 41.35647694111013, "Cytomegalovirus infection reactivation ": 80.80282490665593, "Deafness ": 18.3052108148416, "Febrile neutropenia ": 20.523005794198767, "Focal nodular hyperplasia ": 679.6024211412794, "Graft versus host disease in gastrointestinal tract ": 177.81909816834084, "Graft versus host disease in skin ": 66.86096760754364, "Haematotoxicity ": 34.0783825233434, "Hepatotoxicity ": 15.106087171396371, "Leukopenia ": 2.96137769703598, "Medulloblastoma recurrent ": 2815.918222338205, "Mucosal inflammation ": 62.6153191884963, "Multiple organ dysfunction syndrome ": 4.057598456527057, "Myelodysplastic syndrome ": 13.236047168380043, "Myelosuppression ": 4.700370594290437, "Nervous system disorder ": 14.202169728341207, "Neurotoxicity ": 10.093362038127054, "Neutropenia ": 14.35940609681729, "Off label use ": 3.176041839849927, "Osteosarcoma ": 502.9693174763792, "Pancytopenia ": 2.3438655669244155, "Platelet count decreased ": 2.7444765210459163, "Pneumonia cytomegaloviral ": 65.051301155106, "Product use in unapproved indication ": 5.141231068359846, "Pulmonary arterial hypertension ": 17.042966491558634, "Respiratory distress ": 3.198589154126713, "Second primary malignancy ": 28.662096829500527, "Sepsis ": 5.875374627324435, "Short stature ": 605.5471836042957, "Stomatitis ": 5.199218308356958, "Thrombocytopenia ": 13.79268024687211, "Thrombotic microangiopathy ": 28.27481572516789, "Venoocclusive liver disease ": 49.76301641465533, "Visual impairment ": 6.677342690487749}
\ No newline at end of file
+{"Acute kidney injury": 5.417591513078398, "Alanine aminotransferase increased": 4.80622794631563, "Aspartate aminotransferase increased": 2.6535811939677347, "Blood alkaline phosphatase increased": 2.867471441805755, "Blood bicarbonate decreased": 55.16388215135517, "Blood creatine phosphokinase increased": 4.284897958206766, "Blood creatinine increased": 9.830290059793509, "Blood phosphorus decreased": 85.43367228710261, "Blood urea increased": 8.805888805590932, "Bone pain": 4.274348497211423, "Chronic hepatitis B": 389.0990288891209, "Chronic kidney disease": 14.40086325493597, "Drug ineffective": 2.027192062887665, "Drug resistance": 12.66793728472928, "Drug-induced liver injury": 2.310022693378381, "Fanconi syndrome": 270.4801030760049, "Fanconi syndrome acquired": 274.5703555001742, "Femur fracture": 9.745262188288708, "Foetal exposure during pregnancy": 3.4396858486596025, "Glomerular filtration rate decreased": 26.25382620265648, "Glycosuria": 208.0560519742387, "Hepatitis B": 66.05944286504219, "Hepatitis B DNA increased": 193.33614043315708, "Hepatitis B reactivation": 90.9693594286036, "Hypokalaemia": 4.552127168458829, "Hypophosphataemia": 127.26828519478757, "Hypophosphataemic osteomalacia": 846.721781779316, "Immune reconstitution inflammatory syndrome": 12.867663194107063, "Lactic acidosis": 3.481036080947576, "Maternal exposure during pregnancy": 6.16179687642922, "Metabolic acidosis": 15.265377300721712, "Multiple organ dysfunction syndrome": 2.5388572546855173, "Nephrogenic diabetes insipidus": 40.97437493593878, "Nephropathy toxic": 36.3441495212082, "Osteomalacia": 99.17814845409876, "Osteopenia": 5.189291991228509, "Osteoporosis": 8.634721512900589, "Proteinuria": 24.1606279256998, "Rebound effect": 118.93981745434986, "Renal failure": 3.5900369824311653, "Renal impairment": 13.01960026871292, "Renal tubular acidosis": 160.38798791436352, "Renal tubular disorder": 435.4851892212097, "Renal tubular dysfunction": 371.5404758912924, "Renal tubular necrosis": 22.580582914456304, "Treatment noncompliance": 7.879381013301568, "Tubulointerstitial nephritis": 5.814511798411333, "Viral load increased": 51.89174899445597}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/107.json
index cf8d96a7c54..b2a9dd8de5f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/107.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 4.064997406100146, "Abnormal weight gain ": 3.2338208339504115, "Acarodermatitis ": 40.26032343992639, "Adverse drug reaction ": 2.173322791081207, "Affect lability ": 2.743349457086406, "Affective disorder ": 27.39554159687701, "Aggression ": 4.105577467185708, "Agitation ": 4.197341503834913, "Akathisia ": 85.11145305960358, "Alcohol abuse ": 12.2509768347496, "Anosognosia ": 42.1618890718443, "Anticholinergic syndrome ": 12.204571865402157, "Antipsychotic drug level above therapeutic ": 18.31097742769342, "Antipsychotic drug level below therapeutic ": 447.9641777227113, "Antipsychotic drug level increased ": 15.020719432282585, "Anxiety disorder ": 2.504178228267331, "Appetite disorder ": 2.5827948639750606, "Arteriosclerosis coronary artery ": 5.499371314830549, "Asphyxia ": 2.117518661945191, "Attention deficit hyperactivity disorder ": 2.7461827916883035, "Autonomic nervous system imbalance ": 6.514533841453183, "Basilar artery occlusion ": 87.24618100475831, "Behaviour disorder ": 3.2742267529208524, "Blood albumin decreased ": 8.767597480990874, "Blood creatine phosphokinase increased ": 3.559795083745246, "Blood creatinine decreased ": 3.466555725128508, "Blood insulin increased ": 20.42274415744563, "Blood magnesium increased ": 37.47635948954606, "Blood osmolarity increased ": 20.72789796737924, "Blood prolactin abnormal ": 57.97388693645858, "Blood prolactin increased ": 15.305654980635182, "Blood thyroid stimulating hormone increased ": 7.611731798884625, "Blood triglycerides increased ": 2.5351018818900397, "Blood urea increased ": 2.6548767652603, "Body dysmorphic disorder ": 28.42816700901442, "Body mass index increased ": 11.420850172538229, "Bradykinesia ": 4.68858286478198, "Bruxism ": 10.68217845131717, "Bundle branch block right ": 2.6765516551233097, "C-reactive protein increased ": 2.3449755784753115, "Cardiac dysfunction ": 14.912323591567514, "Cardio-respiratory arrest ": 3.776769937929492, "Cardiomegaly ": 3.375218720684637, "Cardiomyopathy ": 3.614045520542221, "Catatonia ": 28.410243610143063, "Cellulitis ": 3.0785430462790075, "Child abuse ": 222.18240029466912, "Choreoathetosis ": 18.15947099117203, "Clang associations ": 522.9912480746402, "Clonus ": 5.28961378134356, "Cogwheel rigidity ": 57.70585410793287, "Coma scale abnormal ": 4.673031034860035, "Completed suicide ": 4.907639041778065, "Coordination abnormal ": 2.8786317940678807, "Decreased eye contact ": 50.29139779731898, "Delirium ": 2.220644696215056, "Delusion ": 20.01182156367929, "Delusion of grandeur ": 417.46826283698624, "Delusional disorder, unspecified type ": 16.97342171461172, "Depressed mood ": 2.12479692217687, "Depression suicidal ": 2.754034204856714, "Depressive symptom ": 2.8521885842704187, "Dermatitis atopic ": 7.039105799948315, "Diastolic dysfunction ": 13.66317325269608, "Diet refusal ": 12.592630827101331, "Dilatation atrial ": 32.401935786044035, "Disinhibition ": 245.11395618419272, "Disorganised speech ": 6.310039876585936, "Distractibility ": 26.59700556124256, "Disturbance in social behaviour ": 18.907047076525146, "Drooling ": 5.505312935719867, "Drug abuse ": 3.426287647501729, "Drug dependence ": 2.3615565393201656, "Drug effective for unapproved indication ": 2.2516969855361, "Drug ineffective ": 3.25340315548129, "Drug ineffective for unapproved indication ": 2.2124996322347488, "Drug interaction ": 4.666860812128974, "Drug level below therapeutic ": 16.41116639755399, "Drug level increased ": 18.927815436184662, "Drug resistance ": 3.706426213916204, "Dysarthria ": 2.417256057479589, "Dyskinesia ": 5.893708788309645, "Dyslipidaemia ": 34.64062511994929, "Dystonia ": 20.93701941470701, "Dystonic tremor ": 87.28133091259639, "Echocardiogram abnormal ": 35.34326416617147, "Ejection fraction abnormal ": 7.309745540375416, "Electrocardiogram QRS complex prolonged ": 5.1379525926505805, "Electrocardiogram QT prolonged ": 11.210167447230132, "Electrocardiogram ST segment elevation ": 2.22761095216364, "Enuresis ": 3.533273689343762, "Eosinophil count decreased ": 5.29892588856096, "Epidural lipomatosis ": 126.92865730341845, "Euphoric mood ": 65.51680408895152, "Exercise lack of ": 36.91344894337186, "Extrapyramidal disorder ": 49.71137312490698, "Feeling guilty ": 9.991956928369166, "Fibrosis ": 4.04249192681621, "Foetal disorder ": 66.23098502811347, "Food craving ": 12.503472841667328, "Galactorrhoea ": 4.747142421447222, "Gambling disorder ": 9.532978621218872, "Gaze palsy ": 3.355255353087626, "Globulins increased ": 138.21192701213536, "Glomerular filtration rate decreased ": 2.990640585915975, "Gynaecomastia ": 5.567180546832834, "Hallucination, auditory ": 26.46381726033198, "Hallucination, tactile ": 79.60494627119607, "Hallucination, visual ": 4.871560546516728, "Hallucinations, mixed ": 10.30444529928772, "Head titubation ": 34.14931260645772, "Hepatic fibrosis ": 4.629840248078052, "Herpes simplex ": 5.0937355205259935, "High density lipoprotein decreased ": 23.527148350132716, "Homicidal ideation ": 6.961820042766228, "Hospitalisation ": 2.444667646483264, "Hypercapnia ": 4.559236591096972, "Hyperkinesia ": 6.00661033611456, "Hypernatraemia ": 2.90542864341034, "Hyperphagia ": 8.616134703795868, "Hyperprolactinaemia ": 31.138686187810755, "Hyperreflexia ": 5.257311402388835, "Hypersexuality ": 17.839528543460126, "Hypertonia ": 6.1607699512230045, "Hypomania ": 16.67201745041211, "Hypophagia ": 3.1379962320046646, "Hyporeflexia ": 3.150018199461718, "Hypoventilation ": 4.25043684137485, "Hypovolaemia ": 2.527935899172644, "Impulsive behaviour ": 5.238671227295008, "Incorrect dose administered ": 3.075388076211569, "Increased appetite ": 53.62855523011491, "Intentional overdose ": 2.745510753742048, "Intentional product misuse ": 3.1354624893195746, "Intentional self-injury ": 4.344609136199009, "Intracranial pressure increased ": 8.298674014085774, "Iron deficiency ": 2.778131293685698, "Iron deficiency anaemia ": 3.550384311307794, "Iron metabolism disorder ": 68.73750605881673, "Irritability ": 4.686009930732643, "Juvenile idiopathic arthritis ": 8.318444244867306, "Left atrial dilatation ": 70.76812422138548, "Left ventricular dysfunction ": 16.875062162135812, "Leukaemia ": 29.141245774450045, "Leukocytosis ": 5.213339869676421, "Leukopenia ": 9.876281019446289, "Logorrhoea ": 3.9993227028455474, "Low birth weight baby ": 5.164813251049623, "Low density lipoprotein increased ": 3.670973717715072, "Lymphocyte count abnormal ": 147.01611245066317, "Lymphocyte count decreased ": 17.935804039484506, "Lymphocyte count increased ": 9.74018195540024, "Mania ": 9.613997180296854, "Maternal exposure during pregnancy ": 2.192177892259071, "Mean cell haemoglobin concentration decreased ": 11.68731339176432, "Mean cell haemoglobin decreased ": 13.97068263833318, "Mean cell haemoglobin increased ": 8.466790627019492, "Mean cell volume decreased ": 8.81982534180345, "Mental disorder ": 2.7768600865340187, "Mental impairment ": 4.027447556640392, "Metabolic disorder ": 9.3886624329378, "Metabolic syndrome ": 8.848245356332344, "Mitral valve incompetence ": 3.930243467468784, "Monocyte count increased ": 5.406511959835667, "Mood altered ": 4.223109665906919, "Mucosal inflammation ": 4.518729412928821, "Muscle rigidity ": 8.69442998861359, "Mutism ": 20.359318302123377, "Myocarditis ": 2.1106098592159195, "Myoclonic epilepsy ": 4.043547934673387, "Myoclonus ": 2.771875190166911, "Negative symptoms in schizophrenia ": 336.35450396468894, "Negative thoughts ": 5.534869683783612, "Negativism ": 22.98890708770908, "Nephrogenic diabetes insipidus ": 6.075008804696153, "Neuroleptic malignant syndrome ": 16.891524258120143, "Neutropenia ": 2.402313699072564, "Neutropenia neonatal ": 315.0970474243834, "Neutrophil count decreased ": 2.10649359302317, "Neutrophil count increased ": 37.5973461240653, "Neutrophilia ": 3.744807748740549, "Non-alcoholic steatohepatitis ": 15.601449555278444, "Non-high-density lipoprotein cholesterol increased ": 329.22375476520955, "Obesity ": 24.241186139837545, "Obsessive-compulsive disorder ": 117.3795063365944, "Obsessive-compulsive symptom ": 36.54650113837572, "Oculogyric crisis ": 20.9825861799108, "Oppositional defiant disorder ": 56.747105827895965, "Orthostatic hypertension ": 19.919707695499664, "Orthostatic hypotension ": 5.218172251666927, "Overdose ": 2.728068595657529, "Panic disorder ": 5.8393192665911, "Paradoxical drug reaction ": 5.962776736786875, "Paranoia ": 8.105322564801313, "Parkinsonism ": 19.476646667807582, "Persecutory delusion ": 24.16745361524234, "Personality change ": 5.008573926948478, "Poisoning deliberate ": 2.259781854904412, "Post-traumatic pain ": 34.45165026324748, "Posture abnormal ": 4.453217077207204, "Pregnancy ": 3.740028233587971, "Premature baby ": 4.331184355440571, "Premature delivery ": 12.103564334365316, "Prescribed overdose ": 11.66995420164655, "Priapism ": 8.957155721246615, "Product administered to patient of inappropriate age ": 3.601808732175522, "Product prescribing error ": 3.5915546525770385, "Product use in unapproved indication ": 3.835707431722695, "Product use issue ": 2.954572614324533, "Progressive multiple sclerosis ": 62.88352257039343, "Psychiatric decompensation ": 7.010423144443448, "Psychiatric symptom ": 2.927547562623122, "Psychomotor hyperactivity ": 5.782475623119649, "Psychomotor retardation ": 9.64387681118675, "Psychotic disorder ": 16.530663174878203, "Psychotic symptom ": 45.83573673100216, "Pulmonary valve incompetence ": 49.95312312673681, "Quadriparesis ": 4.793679542426659, "Rebound effect ": 5.1057221181270105, "Red blood cell count decreased ": 2.6930901219451564, "Red cell distribution width increased ": 21.73103580475072, "Respiratory acidosis ": 4.605727059760719, "Respiratory arrest ": 2.4309440901151875, "Respiratory depression ": 8.268090475588757, "Resting tremor ": 14.277963504671536, "Restless legs syndrome ": 2.884664987085026, "Restlessness ": 3.141733570570855, "Rhinalgia ": 44.787682709061805, "SARS-CoV-2 test positive ": 5.055686036140761, "Salivary hypersecretion ": 12.638884327685249, "Schizoaffective disorder ": 398.5707204731624, "Schizophrenia ": 55.59312275978137, "Sedation ": 15.833328665914992, "Sedation complication ": 29.505922060677715, "Self-destructive behaviour ": 4.178092668908295, "Self-injurious ideation ": 2.8863381867070266, "Self-medication ": 8.77257362637516, "Serotonin syndrome ": 8.620531324107283, "Sexual dysfunction ": 10.466426764176166, "Sinus bradycardia ": 2.422914860907392, "Sinus rhythm ": 101.9993437467453, "Sinus tachycardia ": 6.621682081730261, "Social anxiety disorder ": 48.88008588345872, "Social avoidant behaviour ": 9.2047101143297, "Somatic symptom disorder ": 9.34803831619484, "Spasmodic dysphonia ": 83.15261524671358, "Staring ": 3.8802920195878094, "Steatohepatitis ": 32.999233738993965, "Streptococcal infection ": 4.487499886645684, "Substance use ": 12.077966528559744, "Suicidal behaviour ": 4.0640797031411084, "Suicidal ideation ": 3.1130531623117155, "Suicide attempt ": 11.118826854885564, "Suspected suicide ": 10.09989538590415, "Sydenham's chorea ": 449.1255590127831, "Systolic dysfunction ": 44.36758355966221, "Tardive dyskinesia ": 25.34287686097129, "Tearfulness ": 2.079278683547065, "Tenderness ": 3.8349396066396895, "Tension ": 3.481964684966067, "Thalassaemia ": 71.05726999832552, "Therapeutic product effect incomplete ": 9.361426855363664, "Therapeutic product effect variable ": 274.25936814407856, "Therapeutic response decreased ": 2.7355636651722373, "Therapy non-responder ": 2.1016553052772387, "Thinking abnormal ": 3.886836219375753, "Thoracic vertebral fracture ": 5.004138490426339, "Thyroxine decreased ": 69.84664286368881, "Torticollis ": 8.550532260448895, "Toxicity to various agents ": 7.685911246360181, "Treatment noncompliance ": 8.514982289072623, "Tri-iodothyronine decreased ": 102.5309717712155, "Tricuspid valve incompetence ": 3.744870005923802, "Trismus ": 4.483651446744608, "Troponin T increased ": 33.05399402030148, "Troponin increased ": 7.415469978575703, "Urinary incontinence ": 2.020438328280321, "Ventricular hypokinesia ": 3.842878452608796, "Victim of child abuse ": 113.05093529601352, "Vitamin B12 increased ": 52.63814127375192, "Weight abnormal ": 15.918601568440556, "Weight increased ": 8.56854107266457, "White blood cell count increased ": 2.2014333628548237}
\ No newline at end of file
+{"Alanine aminotransferase abnormal": 110.52070008424252, "Alanine aminotransferase increased": 3.219699621697369, "Anal atresia": 952.249070345796, "Anencephaly": 784.0312787137402, "Aspartate aminotransferase abnormal": 209.5312950032599, "Bladder agenesis": 39404.1228813144, "Blood alkaline phosphatase increased": 10.626364852276328, "Blood bilirubin increased": 17.35154857583515, "Blood iron decreased": 123.41799091410346, "Caudal regression syndrome": 2636.088350718861, "Cholelithiasis": 41.75148063711991, "Cloacal exstrophy": 17988.291258625384, "Congenital anomaly": 65.95198645740592, "Congenital ectopic bladder": 5543.213819601852, "Congenital genital malformation": 1569.8309245199737, "Congenital musculoskeletal disorder": 547.0517563409115, "Congenital musculoskeletal disorder of spine": 1140.4637512091592, "Drug-induced liver injury": 6.756263211682231, "Erythema": 2.7625540431608644, "Exomphalos": 901.5852294731764, "Exposure during pregnancy": 5.743266026759097, "Fibrosis": 124.22201749932825, "Foetal exposure during pregnancy": 5.654519907981118, "Gastrointestinal disorder congenital": 4701.065232172242, "Gastrointestinal malformation": 1714.2496582015333, "Genitalia external ambiguous": 3472.013490665753, "Hepatic cytolysis": 10.8942409411567, "Hepatic enzyme increased": 7.6700180362842625, "Hepatotoxicity": 12.607378882023747, "Hypomania": 58.1016134272866, "Jaundice": 19.5686164861567, "Jaundice cholestatic": 51.086931422449055, "Lipodystrophy acquired": 313.1885069513086, "Pneumonia": 3.698393232766496, "Premature labour": 50.64353106010293, "Product use in unapproved indication": 2.6649504644446664, "Psychotic disorder": 9.227838194335083, "Schizophrenia": 116.30765672503898, "Tinnitus": 3.683780988840986, "Vomiting": 2.3335272778467693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1070.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1070.json
index 6a1c96c2b25..4a155a27129 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1070.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1070.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 227.04082780582536, "Maternal exposure during pregnancy ": 96.34696146561234}
\ No newline at end of file
+{"Acute graft versus host disease": 465.04008749833, "Graft versus host disease": 383.9366784620941, "Mucosal inflammation": 61.453650752156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1071.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1071.json
index d165cae480a..1dc2efd0b42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1071.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1071.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 4.833472647267703, "Acute kidney injury ": 2.468818293486269, "Acute myocardial infarction ": 8.448810431637515, "Amaurosis ": 39.52333191306073, "Angina unstable ": 5.615154263583051, "Asphyxia ": 37.63570374965063, "Atrioventricular block ": 5.77635850162484, "Atrioventricular block complete ": 6.731418726769471, "Blood loss anaemia ": 50.74725054408197, "Bronchial haemorrhage ": 95.99923570525895, "Cardiogenic shock ": 3.040671287583894, "Cerebral haemorrhage ": 7.171756197195853, "Chest discomfort ": 9.460401999354136, "Chronic gastritis ": 48.18818488575063, "Conjunctival haemorrhage ": 10.210196166291176, "Coronary artery occlusion ": 6.677786758875344, "Coronary artery stenosis ": 15.183550255424525, "Diarrhoea haemorrhagic ": 10.417887976840806, "Drug interaction ": 4.957388398314164, "Duodenal ulcer ": 15.889728071557718, "Duodenal ulcer haemorrhage ": 32.86101281959504, "Dyspnoea ": 4.729598761683767, "Dyspnoea at rest ": 16.622340433961543, "Ecchymosis ": 19.24954589386545, "Electrocardiogram ST segment elevation ": 6.6434971709886135, "Epistaxis ": 6.616247987252902, "Eye haemorrhage ": 2.471622456330378, "Faeces discoloured ": 16.77884091353526, "Gastric haemorrhage ": 9.73669946209261, "Gastric mucosal lesion ": 67.19114694267986, "Gastric ulcer ": 7.5418794805671965, "Gastric ulcer haemorrhage ": 20.12180399203093, "Gastritis erosive ": 18.46889262153336, "Gastrointestinal haemorrhage ": 26.04518349788933, "Gingival bleeding ": 14.890783877736542, "Gout ": 5.717688853474336, "Haematemesis ": 32.75904461306297, "Haematochezia ": 17.490500659589728, "Haematoma ": 3.075330957252272, "Haematuria ": 9.169292620862317, "Haemoglobin decreased ": 6.542218569003436, "Haemoptysis ": 11.78474493545197, "Haemorrhage ": 3.423993774908652, "Haemorrhage intracranial ": 12.488215838481278, "Haemorrhage subcutaneous ": 28.148778203318603, "Haemorrhage urinary tract ": 13.819169447400435, "Haemorrhoidal haemorrhage ": 10.6583566207891, "Haemothorax ": 11.45930800695112, "Incorrect dose administered ": 2.1559789812340373, "Iron deficiency anaemia ": 4.469980941847617, "Labelled drug-drug interaction issue ": 220.60996919041324, "Labelled drug-drug interaction medication error ": 199.4374895009144, "Lower gastrointestinal haemorrhage ": 62.99539964068568, "Melaena ": 59.43854388157198, "Myopathy ": 4.604628449945429, "Occult blood positive ": 35.740598372901744, "Pericardial haemorrhage ": 16.089366722855882, "Platelet aggregation inhibition ": 471.91629779597486, "Post procedural haemorrhage ": 5.864217060738054, "Product administration error ": 3.3964352939835822, "Product prescribing issue ": 28.85639652403592, "Pulmonary alveolar haemorrhage ": 14.28467889812784, "Pulmonary haemorrhage ": 14.73140373657302, "Purpura ": 2.5606403193661684, "Rectal haemorrhage ": 4.633215208097326, "Respiratory rate increased ": 6.941773923038289, "Respiratory tract haemorrhage ": 38.35344174403821, "Rhabdomyolysis ": 12.100416845817044, "Shock haemorrhagic ": 8.554998460301464, "Sinus arrest ": 44.90060240060416, "Subarachnoid haemorrhage ": 11.808347174243016, "Subdural haematoma ": 4.562433482018913, "Tachypnoea ": 8.387425090653139, "Thrombotic thrombocytopenic purpura ": 6.361380751466973, "Treatment noncompliance ": 2.6151451612268586, "Upper gastrointestinal haemorrhage ": 123.53121169706012, "Vascular stent thrombosis ": 30.77366095198895, "Ventricular asystole ": 129.26035004649873}
\ No newline at end of file
+{"Nausea": 3.5380030778930496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1072.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1072.json
index 7ab3e7affcd..f5fc06d5c10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1072.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1072.json
@@ -1 +1 @@
-{"Acinetobacter infection ": 279.0412634880268, "Acute respiratory distress syndrome ": 22.622277115187547, "Bacteraemia ": 36.50545089236813, "Blood bilirubin increased ": 5.640249190247344, "Coagulopathy ": 13.385699435208718, "Condition aggravated ": 4.308569571404217, "Drug ineffective ": 6.491071222586458, "Drug resistance ": 27.81282443104805, "Electrocardiogram QT prolonged ": 4.713881439747022, "Hepatic function abnormal ": 6.831461780872209, "Klebsiella infection ": 173.65006107216314, "Liver function test abnormal ": 10.803848506217888, "Liver injury ": 10.461446568340955, "Mental status changes ": 13.065675539197924, "Off label use ": 3.912522559215336, "Pancreatitis acute ": 7.469700010507458, "Pathogen resistance ": 136.85464308207028, "Platelet count decreased ": 3.361274845497193, "Product use issue ": 3.2802729536254747, "Pseudomembranous colitis ": 42.06122203494714, "Sepsis ": 4.96673712352168, "Septic shock ": 8.16353936224208, "Thrombocytopenia ": 2.622345071050122, "Tinnitus ": 3.817653691905613}
\ No newline at end of file
+{"Alanine aminotransferase increased": 2.27424550433732, "Alopecia": 5.218457105556481, "Back pain": 2.35408132758621, "Balance disorder": 4.788713031039936, "Depressed mood": 3.6773538294595913, "Fall": 3.459173184360765, "Gait disturbance": 3.3533611742158804, "Hepatic enzyme increased": 3.7271520613998126, "Hypoaesthesia": 3.1773718405128504, "Memory impairment": 3.1825561538104483, "Multiple sclerosis": 35.87273619557571, "Multiple sclerosis relapse": 74.31171249524328, "Product substitution issue": 14.914393889373814, "Unevaluable event": 7.398559640031065, "Urinary tract infection": 3.0511830535556634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1073.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1073.json
index 3593444ea49..67ce5079592 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1073.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1073.json
@@ -1 +1 @@
-{"Arrhythmia ": 7.027505058064821, "Atrial fibrillation ": 24.69335469179725, "Drug interaction ": 5.800276807716031, "Electrocardiogram QT prolonged ": 10.489360458467567, "Heart rate decreased ": 14.197114362627648, "Heart rate increased ": 6.239990256040112, "Visual impairment ": 3.519889071561064}
\ No newline at end of file
+{"Back pain": 3.2535292471658583, "Bone pain": 4.1287137660365465, "Calciphylaxis": 159.30080992833138, "Fall": 5.765425314138002, "Femur fracture": 16.10478800098519, "Hip fracture": 15.484716274988267, "Hospitalisation": 2.0386633959000635, "Hypercalcaemia": 76.67013068304536, "Muscle spasms": 2.469262203061878, "Nephrolithiasis": 6.143134211067866, "Renal impairment": 2.354725013778273, "Skin necrosis": 19.31323140631608, "Spinal compression fracture": 18.35043349921976, "Spinal fracture": 13.013928960845346, "Upper limb fracture": 19.51463055554854}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1074.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1074.json
index 486bb65ce1c..4ccbee9a4a3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1074.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1074.json
@@ -1 +1 @@
-{"Acute kidney injury ": 6.690969155934481, "Acute lymphocytic leukaemia recurrent ": 213.7602463923735, "Cytokine release syndrome ": 372.884739585333, "Diffuse large B-cell lymphoma ": 116.7143615763726, "Disease progression ": 5.537481926080544, "Disseminated intravascular coagulation ": 38.38684237003344, "Encephalopathy ": 28.856036376113, "Febrile neutropenia ": 13.811249080970205, "Haemophagocytic lymphohistiocytosis ": 61.20934212873309, "Hypotension ": 4.229529676385023, "Hypoxia ": 17.688184690083133, "Immune effector cell-associated neurotoxicity syndrome ": 378.3965970313274, "Lymphopenia ": 75.03930993327171, "Malignant neoplasm progression ": 2.229553208403124, "Neurotoxicity ": 33.45867697076864, "Neutropenia ": 3.2785808705731547, "Neutrophil count decreased ": 22.27787845533811, "Platelet count decreased ": 5.951540828268608, "Sepsis ": 4.639928608539302, "Tumour lysis syndrome ": 45.50688407212719, "White blood cell count decreased ": 12.273883794568777}
\ No newline at end of file
+{"Back pain": 4.502696978429284, "Bone pain": 6.888177846802693, "Device malfunction": 17.42239485942071, "Dizziness": 2.975360160046048, "Injection site bruising": 42.52910538142604, "Injection site erythema": 4.430756947462962, "Injection site haemorrhage": 26.57497786214627, "Muscle spasms": 3.495796094787281, "Nausea": 2.087133447193419, "Pain in extremity": 2.7383340065924853, "Palpitations": 3.018722676984012, "Product dose omission issue": 5.198305610758029, "Therapy interrupted": 62.73146371117658, "Wrong technique in device usage process": 44.20027338226655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1075.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1075.json
index c67e29a61fa..14cae3ad503 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1075.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1075.json
@@ -1 +1 @@
-{"Myelosuppression ": 150.64707793241547, "Neutrophil count decreased ": 47.262203783402434, "Off label use ": 2.4125997107597814, "Platelet count decreased ": 25.45588638138306, "White blood cell count decreased ": 40.15888725408857}
\ No newline at end of file
+{"Accidental exposure to product": 12.080499856820271, "Acne": 9.440369199313349, "Acute myocardial infarction": 17.576976517201253, "Aggression": 4.498486436025834, "Anger": 5.383876922768514, "Angina pectoris": 2.889259044182473, "Aortic aneurysm": 18.17837141989954, "Arteriosclerosis": 10.676505452687696, "Atrial fibrillation": 2.0034923906712687, "Blood testosterone decreased": 85.91153653197748, "Blood testosterone increased": 412.3866340747055, "Bone disorder": 7.113804647529053, "Breast cancer": 3.892036576317762, "Breast cancer metastatic": 8.902801016524183, "Cardiac death": 98.66579407767033, "Cardiac failure congestive": 2.172523167707363, "Cardiomyopathy": 7.362062427575814, "Cerebrovascular accident": 4.418975651837623, "Cholestasis": 3.101375735972487, "Coronary artery disease": 11.646528459185175, "Coronary artery occlusion": 6.848311564568541, "Deep vein thrombosis": 15.422624290547953, "Device dislocation": 34.05992900066411, "Device malfunction": 6.032849269129476, "Drug abuse": 12.926828588353708, "Drug-induced liver injury": 2.559959420775908, "Dyslipidaemia": 9.386557677931464, "Endometrial cancer": 45.62416534941225, "Erectile dysfunction": 5.835781165615611, "Gynaecomastia": 7.10372429034173, "Hair growth abnormal": 28.38329845833128, "Idiopathic intracranial hypertension": 65.5316144352414, "Intentional product misuse": 3.0406896463845103, "Invasive ductal breast carcinoma": 17.39926159304209, "Jaundice": 3.0760270732134494, "Left ventricular hypertrophy": 46.41696567317301, "Libido decreased": 7.04483245600222, "Mesenteric vein thrombosis": 49.82377531698251, "Muscle mass": 194.53045341531097, "Myocardial fibrosis": 91.75883416578648, "Myocardial infarction": 4.292764777491754, "Obstructive sleep apnoea syndrome": 27.240806841862785, "Oestradiol increased": 181.24167592430973, "Off label use": 2.683094544723802, "Osteonecrosis": 3.183937228998872, "Papilloedema": 18.124087432693496, "Polycythaemia": 193.6453657717842, "Portal vein thrombosis": 22.914358530816408, "Precocious puberty": 179.91027558289872, "Prescription drug used without a prescription": 22.59359349114965, "Product quality issue": 13.846996295569904, "Product use in unapproved indication": 2.859849532029431, "Product use issue": 7.471237596419519, "Prostate cancer": 6.6830260146961855, "Prostatic specific antigen increased": 9.965604403503, "Pulmonary embolism": 9.053819098044029, "Self-medication": 58.86283737018609, "Testicular atrophy": 130.55584368399477, "Therapeutic product effect decreased": 2.214050043694165, "Thrombosis": 2.8968926194906124, "Transgender hormonal therapy": 3969.856152227744, "Virilism": 925.5841314939246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1076.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1076.json
index d60eb04676c..b08fab22562 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1076.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1076.json
@@ -1 +1 @@
-{"Abnormal dreams ": 7.369999789464062, "Amnesia ": 2.595667529497314, "Blood HIV RNA increased ": 113.2947565518387, "Blood calcium increased ": 10.782368581468528, "Blood creatine phosphokinase increased ": 3.699981670724645, "Blood creatinine increased ": 4.0523572205468845, "Cholestasis ": 2.9158428083437973, "Deafness ": 2.841806514409853, "Depressed mood ": 3.033685811126822, "Depression ": 2.839720441796729, "Dermatitis ": 4.247386074521855, "Drug resistance ": 3.075588478323166, "Dysuria ": 3.0409831746805933, "Glomerular filtration rate decreased ": 4.202684904602609, "Hepatic cytolysis ": 2.5171205234106626, "Hepatic failure ": 2.2570005405403166, "Hepatitis ": 4.701953903118595, "Hospitalisation ": 3.4045985499987865, "Hyperlipidaemia ": 6.78991836222758, "Immune reconstitution inflammatory syndrome ": 117.08157361621396, "Inhibitory drug interaction ": 40.90244930920812, "Insomnia ": 3.201936467142211, "Intervertebral disc disorder ": 25.18928080442944, "Jaundice ": 2.113807371817753, "Kaposi's sarcoma ": 36.84762850203537, "Lactic acidosis ": 2.584505602748674, "Lipodystrophy acquired ": 16.553652358115084, "Liver function test abnormal ": 2.8860344175572226, "Liver function test increased ": 3.2125968792793502, "Lymphoma ": 10.450593910608385, "Major depression ": 16.01999119556906, "Mental disorder ": 5.391991499208519, "Mycoplasma infection ": 155.73506054310172, "Nephropathy ": 3.4347291586537425, "Nervous system disorder ": 4.602720773527096, "Nervousness ": 2.4960177052602344, "Neurotoxicity ": 23.15917344924086, "Nightmare ": 5.080839812983594, "Osteopenia ": 3.734166142319564, "Pancreatitis ": 2.5533012752926343, "Pathogen resistance ": 11.68661893294461, "Pneumocystis jirovecii pneumonia ": 7.291528400449626, "Progressive multifocal leukoencephalopathy ": 20.686411956313982, "Proteinuria ": 2.5393731250062097, "Psychotic disorder ": 2.9926273487737465, "Renal failure ": 2.317494151286797, "Renal impairment ": 3.805343784163744, "Sleep disorder ": 3.6675845786876895, "Suicidal ideation ": 6.1280402287620594, "Suicide attempt ": 2.0921659789941742, "Transaminases increased ": 3.5362557579820164, "Treatment noncompliance ": 6.366920213471998, "Tuberculosis ": 12.91509444304382, "Upper-airway cough syndrome ": 29.04998167215432, "Urethral discharge ": 1037.6759625949808, "Urethritis ": 120.02154130022788, "Viral load increased ": 42.6312920656961, "Viral mutation identified ": 23.3951337681442, "Virologic failure ": 13.700562716154405, "Weight increased ": 2.5727958342652557}
\ No newline at end of file
+{"Bone pain": 27.846789229238368, "Drug ineffective": 7.129510721873197, "Erythema": 6.323156581725332}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1077.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1077.json
index 56b5c49d294..47a8d9ca9d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1077.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1077.json
@@ -1 +1 @@
-{"Bronchospasm ": 71.21449624211903, "Chest discomfort ": 8.083505292931292, "Condition aggravated ": 2.514484175069501, "Cough ": 12.825390400611669, "Cystic fibrosis ": 706.7825124193597, "Death ": 2.662542502907519, "Drug intolerance ": 7.478322078284209, "Dyspnoea ": 4.937798022050716, "Forced expiratory volume decreased ": 189.36367883747508, "Haemoptysis ": 72.22021283293803, "Infection ": 4.371839808250974, "Lower respiratory tract infection ": 10.94610738108935, "Oxygen saturation decreased ": 12.154623634098035, "Pneumonia ": 3.457184468562118, "Pulmonary function test decreased ": 166.51235418965229, "Wheezing ": 9.034577800287948}
\ No newline at end of file
+{"Product use in unapproved indication": 20.188251769515823}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1078.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1078.json
index a9d76304a25..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1078.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1078.json
@@ -1 +1 @@
-{"Acute kidney injury ": 13.0797155076361, "Blindness ": 3.5442191013587165, "Blood alkaline phosphatase increased ": 2.270878993529436, "Blood creatinine increased ": 6.760496047570615, "Blood pressure decreased ": 2.054228825580104, "Blood urea increased ": 11.694635508630489, "Bronchospasm ": 9.03659129074215, "Clostridium difficile colitis ": 7.330993510280246, "Colitis ": 6.109173088166035, "Condition aggravated ": 2.067618466170088, "Conjunctivitis ": 4.69846648538013, "Corneal opacity ": 50.27483862616008, "Creatinine renal clearance decreased ": 25.58619062807742, "Cystic fibrosis ": 77.28903628029178, "Deafness ": 7.869634104270363, "Deafness neurosensory ": 46.524488193918536, "Drug clearance decreased ": 142.21029874448897, "Drug hypersensitivity ": 4.071393377598039, "Drug ineffective ": 2.3000945416119776, "Drug level increased ": 19.419871543939724, "Drug resistance ": 9.636538525884005, "Eosinophil count abnormal ": 74.65641238920456, "Eosinophilia ": 4.763391445780803, "Eye pain ": 3.4165936959212977, "Eye swelling ": 3.379485528471644, "Eyelid oedema ": 5.160497237279721, "Graft versus host disease ": 10.042811175242203, "Haemoptysis ": 2.673796057072801, "Hypoacusis ": 5.694307325151266, "Hypopyon ": 63.85817046197631, "Hypotension ": 2.726795557140399, "Incorrect route of product administration ": 3.3041985821778623, "Infection ": 2.1847065729397137, "Keratitis ": 51.800995212431694, "Lactic acidosis ": 2.488585383059465, "Leukocytosis ": 5.886981850906022, "Lung disorder ": 2.7022443059056065, "Multiple organ dysfunction syndrome ": 3.664853757759001, "Nephrolithiasis ": 2.809823942435975, "Nephropathy toxic ": 15.63470794955351, "Ocular hyperaemia ": 6.195404658368457, "Ototoxicity ": 174.24190923011594, "Pathogen resistance ": 45.98290959042277, "Pneumonia pseudomonal ": 53.40531967015604, "Productive cough ": 2.4334306499190306, "Pseudomembranous colitis ": 46.61018151627578, "Pseudomonas infection ": 51.875778004570485, "Pulmonary hypertension ": 4.374604381434981, "Renal impairment ": 4.570455530843854, "Renal tubular necrosis ": 76.80143955603143, "Respiratory disorder ": 5.513658245695871, "Respiratory rate decreased ": 25.097384826881523, "Sepsis ": 2.9687810000304475, "Septic shock ": 6.001593484832365, "Staphylococcal infection ": 6.208773911674653, "Therapy non-responder ": 3.680560491155068, "Tinnitus ": 3.927624229707052, "Toxic anterior segment syndrome ": 55.38051686224862, "Toxic epidermal necrolysis ": 8.230342361227871, "Ulcerative keratitis ": 48.27170811765266, "Visual acuity reduced ": 5.19426476495989, "White blood cell count increased ": 4.034530455565668}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1079.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1079.json
index 8bd7521e23e..b5522be0bf0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1079.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1079.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 2.014991254861531, "Anaphylactic reaction ": 3.16100888584066, "Arthritis ": 4.689665923864119, "C-reactive protein increased ": 2.4315030799917805, "COVID-19 pneumonia ": 7.916775757877641, "Cellulitis ": 7.70476162899105, "Cytokine release syndrome ": 4.824919427073132, "Diverticular perforation ": 57.97647247760111, "Diverticulitis ": 11.816352630252007, "Empyema ": 55.94500559302732, "Haemophagocytic lymphohistiocytosis ": 25.374087184507168, "Hepatic cytolysis ": 2.26173701865858, "Hepatitis ": 6.490518867366277, "Hypercholesterolaemia ": 6.712580878038252, "Hypofibrinogenaemia ": 615.2547251291676, "Hypoxia ": 2.793792458103257, "Infusion related reaction ": 2.5674632269032647, "Intentional product use issue ": 19.627492512694943, "Intestinal perforation ": 23.396485670310167, "Large intestine perforation ": 34.54522123446803, "Leukopenia ": 4.049179285731845, "Neutropenia ": 5.591501546356307, "Neutrophil count decreased ": 2.147475921532841, "No adverse event ": 5.220093348720895, "Off label use ": 7.578902244685533, "Organising pneumonia ": 15.887612891414657, "Pancreatitis acute ": 2.2222536563324087, "Pneumonia ": 2.1753509830563424, "Product use in unapproved indication ": 2.3826606891031403, "Respiratory failure ": 2.242092979196247, "Sepsis ": 4.299022856788757, "Septic shock ": 5.781739902488358, "Staphylococcal infection ": 3.912014760890768, "Therapy non-responder ": 2.250168461349831, "Transaminases increased ": 4.720484109798611, "Urinary tract infection ": 2.03676560152188, "Vasculitis ": 5.825689795595157}
\ No newline at end of file
+{"Asthma": 32.77069085038518}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/108.json
index de6a807d39a..bdd9f5a397a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/108.json
@@ -1 +1 @@
-{"Abdominal wall haematoma ": 70.51519536618059, "Acute generalised exanthematous pustulosis ": 13.558215731959434, "Acute kidney injury ": 2.01767067173518, "Anaemia ": 7.857211504725206, "Blood alkaline phosphatase increased ": 3.456069793688746, "Blood loss anaemia ": 44.05024982817037, "Bronchospasm ": 3.66512353857739, "Cardiac arrest ": 2.228897879388682, "Cerebral haemorrhage ": 11.069180822578817, "Cholestasis ": 5.817716679103597, "Chromaturia ": 11.441608480541724, "Coagulopathy ": 7.904383536646639, "Coma ": 2.305248203011274, "Deep vein thrombosis ": 2.794004113644586, "Dermatitis allergic ": 5.038670178741249, "Drug reaction with eosinophilia and systemic symptoms ": 3.772875855038649, "Eosinophilia ": 6.687854768100896, "Exposure during pregnancy ": 4.472023273172317, "Gamma-glutamyltransferase increased ": 3.6155011095293967, "Gastrointestinal haemorrhage ": 4.525780544756375, "Haematemesis ": 15.211714430613116, "Haematoma ": 41.13495550792344, "Haematoma muscle ": 75.38139348792014, "Haematuria ": 6.903668053939697, "Haemoglobin decreased ": 3.8825875924515976, "Haemorrhage ": 6.716240857934408, "Haemorrhagic stroke ": 12.967585947209905, "Heparin-induced thrombocytopenia ": 17.00200692193224, "Hepatic cytolysis ": 4.972557145476923, "Inflammation ": 2.618577717496235, "International normalised ratio increased ": 4.262828652879841, "Liver injury ": 3.9336780650627032, "Melaena ": 9.260221237153402, "Mixed liver injury ": 32.9126697180814, "Muscle haemorrhage ": 77.7148033002511, "Pulmonary embolism ": 3.0498742035085766, "Rash maculo-papular ": 17.28816975892597, "Rectal haemorrhage ": 6.291578025545048, "Septic shock ": 6.398672618912167, "Shock haemorrhagic ": 55.90311496897804, "Subarachnoid haemorrhage ": 13.267803265070238, "Subdural haematoma ": 28.4468661081193, "Subdural haemorrhage ": 37.39592895397138, "Tendon rupture ": 7.886298648816006, "Thrombocytopenia ": 5.829588616322615, "Transaminases increased ": 4.31299370868001, "Vaginal haemorrhage ": 4.369567826302657}
\ No newline at end of file
+{"Abdominal distension": 18.73176238984267, "Abdominal pain": 4.989509673045357, "Actinic keratosis": 3.2155370306594704, "Activated partial thromboplastin time prolonged": 97.06291853551512, "Anaemia": 8.110606762349367, "Analgesic therapy": 1161.886993037581, "Antacid therapy": 4857.137999716035, "Anti-erythrocyte antibody": 164.6642283935017, "Anti-erythropoietin antibody": 63.481927141659774, "Anti-erythropoietin antibody negative": 92.88429352086015, "Anti-erythropoietin antibody positive": 190.25223389960428, "Antibody test positive": 12.93139075192816, "Anticoagulant therapy": 380.42503665889166, "Aortic arteriosclerosis": 3.055319826070196, "Aortic stenosis": 132.36880454306845, "Aortic valve incompetence": 2.2526262091907507, "Aplasia pure red cell": 171.85716537242172, "Aplastic anaemia": 3.435765640501381, "Appendicitis": 170.4040426531827, "Appendicolith": 2225.452504876328, "Arteriovenous fistula thrombosis": 31.45558775969433, "Ascites": 43.554514796245314, "Aspartate aminotransferase increased": 4.083368310964677, "Aspiration": 7.156391619343679, "Azotaemia": 4.719187238385426, "Bacterial infection": 77.48038192119076, "Bacteroides infection": 2322.6947118828784, "Blood calcium increased": 9.825026634024846, "Blood cholesterol increased": 20.11094953059278, "Blood parathyroid hormone increased": 8.432417403807639, "Blood phosphorus increased": 413.7856330926713, "Blood product transfusion dependent": 25.08298137849933, "Blood test abnormal": 8.899121862981342, "Blood uric acid increased": 128.65282481003018, "Bone marrow disorder": 5.4838905520951045, "Bone marrow failure": 11.298313397937358, "Bronchiectasis": 10.710581860649045, "Calciphylaxis": 6.872483429105612, "Cardiac output decreased": 13.147021519604216, "Cardiogenic shock": 90.55428860315644, "Carotid artery stenosis": 3.0388810680449785, "Caudal regression syndrome": 38.944273764033376, "Chronic obstructive pulmonary disease": 11.384741166799111, "Complications of transplanted kidney": 22.164458039072564, "Condition aggravated": 3.9776460342433664, "Constipation": 9.738703495245796, "Death": 8.112188628039329, "Delayed graft function": 47.87305236498157, "Device difficult to use": 32.493352108021995, "Diabetes mellitus": 14.591062946122324, "Dialysis": 59.38906318091595, "Diffuse alopecia": 4.595192075704749, "Diverticulum intestinal": 4.800340509806133, "Drug dose omission by device": 4.724573211294067, "Drug hypersensitivity": 8.808845220087516, "Drug intolerance": 7.089619003007887, "Drug specific antibody": 9.05850300677316, "Drug specific antibody absent": 136.53636450501443, "Drug specific antibody present": 10.77953892471145, "Drug therapy": 712.9213778540573, "Dry mouth": 6.033491242488925, "End stage renal disease": 2.409788595944646, "Erythropoiesis abnormal": 36.45807734757906, "General physical health deterioration": 11.249111382868575, "Haematocrit decreased": 2.70352504566141, "Haemodialysis": 117.29989186112634, "Haemoglobin abnormal": 46.34517430832325, "Haemoglobin decreased": 9.275835483106544, "Haemoglobin increased": 15.464113856854864, "Hip fracture": 2.9060215694465965, "Hospitalisation": 19.469962326052077, "Hyperparathyroidism": 14.11107369596022, "Hyperparathyroidism secondary": 13.350582286330484, "Hyperphosphataemia": 323.63854751957194, "Hypervolaemia": 3.3277970112457638, "Hyponatraemia": 10.97454381167944, "Hypophosphataemia": 62.26293876340647, "Incorrect route of product administration": 15.689481997524505, "Injection site haemorrhage": 3.259520893363877, "Intentional product misuse": 4.960163562410982, "Iron deficiency": 24.002043816609508, "Iron overload": 11.93860256925485, "Kidney transplant rejection": 5.013283674141334, "Laboratory test abnormal": 2.7919957574002288, "Multiple organ dysfunction syndrome": 13.431323845673074, "Myelodysplastic syndrome": 11.956060322148296, "Myelodysplastic syndrome with single lineage dysplasia": 75.16942991479918, "Myelofibrosis": 2.8829862344137127, "Neutralising antibodies positive": 38.10813106208835, "Non-neutralising antibodies positive": 396.2585641415277, "Normochromic normocytic anaemia": 17.118623679794116, "Normocytic anaemia": 3.054271861689984, "Occult blood positive": 2.7445700887351063, "Pancytopenia": 2.0216098298546825, "Parvovirus B19 infection": 23.23524237815009, "Peritoneal dialysis": 88.77303311505199, "Peritonitis": 4.3002807585614224, "Peritonitis bacterial": 9.571402807340782, "Platelet count abnormal": 3.3381821070898603, "Polycythaemia": 3.376360370985568, "Product storage error": 3.653601046908942, "Red blood cell abnormality": 8.723705557334297, "Rehabilitation therapy": 7.601391093911192, "Renal disorder": 2.014716149628137, "Renal transplant": 44.59099995659517, "Reticulocyte count abnormal": 193.1956313031387, "Reticulocyte count decreased": 111.9777727390904, "Reticulocytopenia": 66.71399294464669, "Sepsis": 6.6111127462891615, "Serum ferritin increased": 4.795525077971171, "Splenomegaly": 2.4006093800247585, "Stress": 14.697131111070831, "Supraventricular tachycardia": 3.6875901370568687, "Terminal state": 12.196159694664072, "Therapeutic response decreased": 18.613193168478396, "Therapy non-responder": 3.1102060668438773, "Transfusion": 14.325729673479849, "Transfusion reaction": 25.49537708645038, "Transplant": 72.57045032065763, "Transplant rejection": 2.125253278576748, "Unevaluable event": 3.04623972329616, "Urine odour abnormal": 3.186631973432911, "Ventricular fibrillation": 8.991325919350492, "Vitamin B12 deficiency": 3.0363889318409263}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1080.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1080.json
index dc410c53252..808e3a902eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1080.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1080.json
@@ -1 +1 @@
-{"Blood creatinine increased ": 6.501998249629692, "Eczema ": 15.21187802587053, "Erythema ": 3.337175232553817, "Swelling ": 4.8010335575525485}
\ No newline at end of file
+{"Acute lymphocytic leukaemia": 15.812596111587196, "Acute myeloid leukaemia": 5.498676222119293, "Acute myocardial infarction": 2.51947590093894, "Atelectasis": 5.550066240676565, "Bone disorder": 4.40870021513675, "Bone lesion": 21.1461499036955, "Bradycardia": 4.764114806166199, "Cardiac failure": 2.8863827873838788, "Constipation": 4.409454140698935, "Cutaneous vasculitis": 5.137814944953071, "Cytopenia": 3.35882551348306, "Death": 3.432036286069746, "Deep vein thrombosis": 12.461071063351248, "Disease progression": 5.423874211474828, "Disorientation": 2.00625300028967, "Drug intolerance": 2.168788886952251, "Drug reaction with eosinophilia and systemic symptoms": 5.232076000148883, "Dysaesthesia": 4.974378184157472, "Embolism": 9.526398187641204, "Febrile neutropenia": 3.443644831636957, "Infection": 2.6350909874578123, "Myelodysplastic syndrome": 6.728775349883188, "Neuropathy peripheral": 36.88426625742378, "Neurotoxicity": 4.854351083876428, "Neutropenia": 2.935639048713188, "Oedema": 2.486531273173087, "Oedema peripheral": 3.145100618655224, "Orthostatic hypotension": 3.313278862760212, "Osteonecrosis of jaw": 12.31537943769507, "Pancytopenia": 4.191613805125339, "Paraesthesia": 2.486029349456597, "Peripheral motor neuropathy": 68.0896975870547, "Peripheral sensory neuropathy": 86.03693107542922, "Plasma cell myeloma": 49.61178118538482, "Plasma cell myeloma recurrent": 46.55714078620445, "Plasmacytoma": 74.41602336223518, "Pneumonia": 2.0727183197664885, "Pneumonitis": 2.956133445462064, "Polyneuropathy": 23.35385164384917, "Pulmonary embolism": 8.641650065482954, "Pulmonary hypertension": 2.786863653378804, "Rash maculo-papular": 3.2109750819015503, "Renal impairment": 2.2589405225942327, "Sepsis": 4.265431141318596, "Septic shock": 2.9667337358143904, "Sinus bradycardia": 4.420869636439437, "Therapy non-responder": 9.95303065310162, "Toxic skin eruption": 3.851538552788668, "Transient ischaemic attack": 2.8797802067650737, "Tumour lysis syndrome": 8.188848339258541, "Type 2 lepra reaction": 200.82207246801983, "Varicella zoster virus infection": 25.852618001457504, "Venous thrombosis limb": 11.007824549815108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1081.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1081.json
index 86bef5d956d..a5dbebc64c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1081.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1081.json
@@ -1 +1 @@
-{"Condition aggravated ": 3.109116022126352, "Cytomegalovirus infection reactivation ": 67.43635724112387, "Deep vein thrombosis ": 5.057627676767332, "Herpes zoster ": 3.9688817048490073, "Joint swelling ": 4.312288669455672, "Off label use ": 2.287158716890312, "Pulmonary embolism ": 5.458139007201937, "Rheumatoid arthritis ": 4.11645173799976, "Treatment failure ": 11.94247258971962}
\ No newline at end of file
+{"Acute lymphocytic leukaemia": 200.72756871358172, "Decreased appetite": 4.9754642239342735, "Febrile neutropenia": 17.563989664438253, "Leukopenia": 10.74683880596742, "Mucosal inflammation": 27.58822158590593, "Myelosuppression": 6.927597858062939, "Stomatitis": 13.94546001504778, "Vomiting": 2.3064690029664376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1082.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1082.json
index 25559ffa50c..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1082.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1082.json
@@ -1 +1 @@
-{"Cough ": 8.733597327554772}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1083.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1083.json
index da73ad2248d..24644f781b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1083.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1083.json
@@ -1 +1 @@
-{"Blood pressure decreased ": 12.857949718216082, "Cardiac failure ": 10.880075358295745, "Drug ineffective ": 2.0522441958704065, "Drug interaction ": 6.088677632461509, "Hypernatraemia ": 175.80328272586783, "Product use in unapproved indication ": 6.1772332372219525, "Renal impairment ": 8.282371217185235, "Sepsis ": 10.057500191384774}
\ No newline at end of file
+{"Acute graft versus host disease": 40.98962384468704, "Acute graft versus host disease in intestine": 162.54282149464166, "Acute graft versus host disease in skin": 191.7586418440809, "Acute promyelocytic leukaemia": 80.76217224837043, "Acute respiratory distress syndrome": 17.10351741163306, "Adenovirus infection": 53.87190121599772, "Anaemia": 4.726986018840199, "Aplastic anaemia": 16.247896771933043, "Chronic graft versus host disease": 39.84050064061359, "Chronic graft versus host disease in skin": 192.51735717586604, "Cystitis haemorrhagic": 41.35647694111013, "Cytomegalovirus infection reactivation": 80.80282490665593, "Deafness": 18.3052108148416, "Febrile neutropenia": 20.523005794198767, "Focal nodular hyperplasia": 679.6024211412794, "Graft versus host disease in gastrointestinal tract": 177.81909816834084, "Graft versus host disease in skin": 66.86096760754364, "Haematotoxicity": 34.0783825233434, "Hepatotoxicity": 15.106087171396371, "Leukopenia": 2.961004387297439, "Medulloblastoma recurrent": 2815.918222338205, "Mucosal inflammation": 62.6153191884963, "Multiple organ dysfunction syndrome": 4.057598456527057, "Myelodysplastic syndrome": 13.236047168380043, "Myelosuppression": 4.700370594290437, "Nervous system disorder": 14.202169728341207, "Neurotoxicity": 10.093362038127054, "Neutropenia": 14.358787677272758, "Off label use": 3.175916712856761, "Osteosarcoma": 502.9693174763792, "Pancytopenia": 2.3438655669244155, "Platelet count decreased": 2.7444765210459163, "Pneumonia cytomegaloviral": 65.051301155106, "Product use in unapproved indication": 5.141070670342077, "Pulmonary arterial hypertension": 17.042966491558634, "Respiratory distress": 3.198589154126713, "Second primary malignancy": 28.662096829500527, "Sepsis": 5.875374627324435, "Short stature": 605.5471836042957, "Stomatitis": 5.199218308356958, "Thrombocytopenia": 13.791380866636636, "Thrombotic microangiopathy": 28.27481572516789, "Venoocclusive liver disease": 49.76301641465533, "Visual impairment": 6.677342690487749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1084.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1084.json
index 605394dcc2f..a15738f1943 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1084.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1084.json
@@ -1 +1 @@
-{"Anaemia ": 6.872565164657599, "Anaplastic lymphoma kinase gene mutation ": 1333.8882349122905, "Blood bilirubin increased ": 4.701416267631148, "Bronchospasm ": 42.62914140024444, "Choroidal dystrophy ": 3234.0518187156263, "Cytopenia ": 12.53149195204519, "Disease progression ": 2.751038524122217, "Disease recurrence ": 10.205481727110444, "Eyelid oedema ": 23.55041516799586, "Eyelid ptosis ": 32.60504106935826, "Febrile neutropenia ": 80.62188377634364, "Haematotoxicity ": 14.682500968407506, "Haematuria ": 2.766400653094257, "Haemoglobin decreased ": 2.9813532911053526, "Interstitial lung disease ": 2.446565015257592, "Leukopenia ": 6.149278453926653, "Lymphocyte count decreased ": 8.37237025275072, "Madarosis ": 111.006133198286, "Malignant neoplasm progression ": 6.125014988030871, "Mucosal inflammation ": 10.095124714877947, "Myelosuppression ": 11.273516311575714, "Neoplasm progression ": 4.272878503168244, "Neuroblastoma ": 528.8684434796431, "Neutropenia ": 17.172452753577932, "Neutrophil count decreased ": 8.934665079638322, "Off label use ": 2.005127058496978, "Pancytopenia ": 14.640763910154396, "Platelet count decreased ": 6.026869172562522, "Product use in unapproved indication ": 6.3898192679136105, "Product use issue ": 4.312006486974255, "Red blood cell count decreased ": 8.22848145155893, "Respiratory failure ": 2.036785588062464, "Retinal vascular occlusion ": 66.39421643281551, "Retinoblastoma ": 3095.191333454762, "Small cell lung cancer ": 69.52729451348233, "Stomatitis ": 2.4378322198150792, "Thrombocytopenia ": 9.149455992278794, "Treatment failure ": 6.504851253767202, "Upper respiratory tract infection ": 5.248301833835703, "Vascular occlusion ": 44.88639736293338, "Vitreous haemorrhage ": 50.29457033338881, "White blood cell count decreased ": 8.70243420292299}
\ No newline at end of file
+{"Abortion spontaneous": 227.04082780582536, "Maternal exposure during pregnancy": 96.34696146561234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1085.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1085.json
index 49d5b7ebecb..6c22cb063d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1085.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1085.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.905409084821205, "Acute respiratory failure ": 3.3555354295531385, "Anaemia ": 2.98562578075412, "Angioedema ": 2.593441455580831, "Aphthous ulcer ": 9.09863849925276, "Ascites ": 3.935584745180045, "Blood alkaline phosphatase increased ": 3.923368540893705, "Blood creatinine increased ": 7.317667885973548, "Blood lactate dehydrogenase increased ": 2.6574965554513503, "Blood triglycerides increased ": 13.50879310967688, "Blood urea increased ": 4.145565248902495, "C-reactive protein increased ": 2.218480462493136, "Cerebral haemorrhage ": 2.760483759069148, "Death ": 4.208830709779996, "Dehydration ": 2.0036839773924124, "Diabetes mellitus ": 3.2700989986205378, "Disease progression ": 32.27406788403763, "Extravasation ": 12.820160625412464, "Febrile neutropenia ": 2.395941843603665, "Flushing ": 5.590008523980762, "General physical health deterioration ": 3.765928004252657, "Haemoptysis ": 2.4054583742737488, "Hypercalcaemia ": 3.94342967994974, "Hyperglycaemia ": 3.779807369931933, "Hyperkalaemia ": 2.122195026933143, "Hyperlipidaemia ": 4.02508443267051, "Hypersensitivity ": 2.250187994703694, "Hypertriglyceridaemia ": 11.689391749696656, "Infusion related reaction ": 4.113035691601546, "Interstitial lung disease ": 25.40951788744201, "Intestinal perforation ": 9.980368857218483, "Lung disorder ": 2.6034988999078728, "Lung infiltration ": 20.929469791936743, "Mantle cell lymphoma ": 140.79980342004131, "Metastatic renal cell carcinoma ": 46.4807089170371, "Microcytic anaemia ": 34.65440871462857, "Mucosal inflammation ": 8.135266549182274, "Nail disorder ": 17.982508451786252, "Neoplasm malignant ": 4.114377887002928, "Neoplasm progression ": 14.6171425037178, "Oedema peripheral ": 2.14909283068786, "Oral pain ": 3.0025155885227512, "Oxygen saturation decreased ": 2.470699428981729, "Pancytopenia ": 2.0059226652056497, "Pericardial effusion ": 3.248567297118669, "Peritonitis ": 5.153673278473041, "Platelet count decreased ": 4.159827025248079, "Pleural effusion ": 9.44131382555991, "Pneumocystis jirovecii pneumonia ": 23.487759819321926, "Pneumonia ": 2.5242735933770377, "Pneumonitis ": 17.297661059169375, "Product use in unapproved indication ": 2.5525002225622377, "Pulmonary fibrosis ": 3.1487357653292696, "Pulmonary oedema ": 2.302689229827512, "Renal cancer ": 11.200809613314249, "Renal cancer metastatic ": 55.3993001874512, "Renal cell carcinoma ": 84.2343429833472, "Renal failure ": 3.3586739360783544, "Stomatitis ": 6.7169809363216375, "Thrombocytopenia ": 3.050698946714851}
\ No newline at end of file
+{"Acute coronary syndrome": 4.833472647267703, "Acute kidney injury": 2.468818293486269, "Acute myocardial infarction": 8.448810431637515, "Amaurosis": 39.52333191306073, "Angina unstable": 5.615154263583051, "Asphyxia": 37.63570374965063, "Atrioventricular block": 5.77635850162484, "Atrioventricular block complete": 6.731418726769471, "Blood loss anaemia": 50.74725054408197, "Bronchial haemorrhage": 95.99923570525895, "Cardiogenic shock": 3.040671287583894, "Cerebral haemorrhage": 7.171756197195853, "Chest discomfort": 9.460068622083837, "Chronic gastritis": 48.18818488575063, "Conjunctival haemorrhage": 10.210196166291176, "Coronary artery occlusion": 6.677786758875344, "Coronary artery stenosis": 15.183550255424525, "Diarrhoea haemorrhagic": 10.417887976840806, "Drug interaction": 4.957388398314164, "Duodenal ulcer": 15.889728071557718, "Duodenal ulcer haemorrhage": 32.86101281959504, "Dyspnoea": 4.729528355974472, "Dyspnoea at rest": 16.622340433961543, "Ecchymosis": 19.24954589386545, "Electrocardiogram ST segment elevation": 6.6434971709886135, "Epistaxis": 6.616247987252902, "Eye haemorrhage": 2.471622456330378, "Faeces discoloured": 16.77884091353526, "Gastric haemorrhage": 9.73669946209261, "Gastric mucosal lesion": 67.19114694267986, "Gastric ulcer": 7.536851715733031, "Gastric ulcer haemorrhage": 20.12180399203093, "Gastritis erosive": 18.44878041359304, "Gastrointestinal haemorrhage": 26.04518349788933, "Gingival bleeding": 14.890783877736542, "Gout": 5.717688853474336, "Haematemesis": 32.75609737472881, "Haematochezia": 17.488758055730678, "Haematoma": 3.075330957252272, "Haematuria": 9.169292620862317, "Haemoglobin decreased": 6.542218569003436, "Haemoptysis": 11.78474493545197, "Haemorrhage": 3.423993774908652, "Haemorrhage intracranial": 12.488215838481278, "Haemorrhage subcutaneous": 28.148778203318603, "Haemorrhage urinary tract": 13.819169447400435, "Haemorrhoidal haemorrhage": 10.6583566207891, "Haemothorax": 11.45930800695112, "Incorrect dose administered": 2.1559789812340373, "Iron deficiency anaemia": 4.468393646110373, "Labelled drug-drug interaction issue": 220.60996919041324, "Labelled drug-drug interaction medication error": 199.4374895009144, "Lower gastrointestinal haemorrhage": 62.99539964068568, "Melaena": 59.43068126127158, "Myopathy": 4.604628449945429, "Occult blood positive": 35.740598372901744, "Pericardial haemorrhage": 16.068820801386895, "Platelet aggregation inhibition": 471.91629779597486, "Post procedural haemorrhage": 5.864217060738054, "Product administration error": 3.396168971554871, "Product prescribing issue": 28.85639652403592, "Pulmonary alveolar haemorrhage": 14.28467889812784, "Pulmonary haemorrhage": 14.73140373657302, "Purpura": 2.5606403193661684, "Rectal haemorrhage": 4.633215208097326, "Respiratory rate increased": 6.941773923038289, "Respiratory tract haemorrhage": 38.35344174403821, "Rhabdomyolysis": 12.100416845817044, "Shock haemorrhagic": 8.554998460301464, "Sinus arrest": 44.90060240060416, "Subarachnoid haemorrhage": 11.808347174243016, "Subdural haematoma": 4.562433482018913, "Tachypnoea": 8.386228561773121, "Thrombotic thrombocytopenic purpura": 6.361380751466973, "Treatment noncompliance": 2.6151451612268586, "Upper gastrointestinal haemorrhage": 123.49584936936108, "Vascular stent thrombosis": 30.77366095198895, "Ventricular asystole": 129.26035004649873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1086.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1086.json
index 96efca172db..3924319e9fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1086.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1086.json
@@ -1 +1 @@
-{"Asphyxia ": 3.1347416653246403, "Blindness ": 5.665544494556956, "Blood glucose abnormal ": 31.597072799389988, "Blood glucose decreased ": 27.680425353446108, "Blood glucose fluctuation ": 36.943233230655885, "Blood glucose increased ": 31.48533019181776, "Caesarean section ": 6.202470264167431, "Cardiac disorder ": 2.6994414625406207, "Cataract ": 7.476190820516678, "Cerebrovascular accident ": 2.801682993135879, "Dementia ": 6.092282818276282, "Device defective ": 35.492507007626386, "Device delivery system issue ": 18.7685460851876, "Device issue ": 29.77402528459545, "Device leakage ": 6.918160748120319, "Device occlusion ": 10.82765539844747, "Device operational issue ": 243.5743004184508, "Diabetes mellitus inadequate control ": 73.25068238530734, "Diabetic ketoacidosis ": 3.78987716326205, "Diabetic metabolic decompensation ": 43.04469094927012, "Disability ": 14.68356855096157, "Drug dose omission by device ": 11.456468695840517, "Drug ineffective ": 2.663614879177066, "Expired product administered ": 3.7689565369952063, "Extra dose administered ": 8.135734389530755, "Eye disorder ": 2.5231741222247206, "Eye haemorrhage ": 3.167798709297984, "Feeling abnormal ": 2.199732907308825, "Glaucoma ": 3.3578785022059754, "Glycosylated haemoglobin abnormal ": 26.25361228980562, "Glycosylated haemoglobin increased ": 29.2511753821142, "Hospitalisation ": 3.132614835169901, "Hyperglycaemia ": 25.28186019143705, "Hypoacusis ": 3.283023781992304, "Hypoglycaemia ": 16.312080791874546, "Hypoglycaemic coma ": 2.698932040269262, "Hypoglycaemic unconsciousness ": 4.741306184073823, "Inappropriate schedule of product administration ": 7.017598988595349, "Incorrect dose administered ": 5.018029843012827, "Incorrect dose administered by device ": 28.157920482205046, "Injection site bruising ": 9.702491641405846, "Injection site haemorrhage ": 6.315330031783683, "Injection site mass ": 4.058109619468821, "Intentional dose omission ": 8.955473371269257, "Intentional product misuse ": 3.832139251058136, "Intentional product use issue ": 4.008458175524142, "Ketoacidosis ": 3.240557177342316, "Loss of consciousness ": 2.022951403150728, "Multiple use of single-use product ": 36.7594532910498, "Needle issue ": 6.434243098805027, "Neoplasm malignant ": 2.424678179938528, "Nervousness ": 3.000444619679882, "Product dispensing error ": 2.7433617618824675, "Product dose omission in error ": 6.405887570616123, "Product dose omission issue ": 4.9971316912930535, "Product prescribing issue ": 4.653400593218763, "Product quality issue ": 10.657454019343618, "Product storage error ": 52.87165737838029, "Product use issue ": 3.8809653362097616, "Renal disorder ": 3.1431770715059093, "Stress ": 2.5029855386445985, "Surgery ": 3.3646165505663075, "Therapeutic response decreased ": 4.557087721233061, "Thirst ": 2.8953953280919102, "Unevaluable event ": 6.197248355539708, "Visual impairment ": 5.016017648068181, "Weight increased ": 2.615702395813786, "Wrong technique in device usage process ": 23.08276218074281}
\ No newline at end of file
+{"Acinetobacter infection": 277.80555008510726, "Acute respiratory distress syndrome": 22.522066524966064, "Bacteraemia": 36.34375560645968, "Blood bilirubin increased": 5.615273390056331, "Coagulopathy": 13.326420063187022, "Condition aggravated": 4.289461761704901, "Drug ineffective": 6.462126082232314, "Drug resistance": 27.68949377920479, "Electrocardiogram QT prolonged": 4.693007721334333, "Hepatic function abnormal": 6.801182166166319, "Klebsiella infection": 172.88050144707557, "Liver function test abnormal": 10.755994371264103, "Liver injury": 10.415109052940736, "Mental status changes": 13.007818977370368, "Off label use": 3.97389821027949, "Pancreatitis acute": 7.436616929245351, "Pathogen resistance": 136.24746640883976, "Platelet count decreased": 3.346382860616958, "Product use issue": 3.2657434304826096, "Pseudomembranous colitis": 41.874952011277145, "Sepsis": 4.944732210962315, "Septic shock": 8.127386617119294, "Thrombocytopenia": 2.779566695119553, "Tinnitus": 3.800741086353969}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1087.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1087.json
index fb392c54c89..ed685c6da02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1087.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1087.json
@@ -1 +1 @@
-{"Accident ": 4.687288606191155, "Anal incontinence ": 2.86666338473011, "Angle closure glaucoma ": 5.705853653412107, "Anticholinergic syndrome ": 14.658867231176783, "Aphonia ": 2.386394544325944, "Back disorder ": 4.491182956468194, "Benign prostatic hyperplasia ": 24.31190126888239, "Bladder dilatation ": 41.391904487724005, "Bladder disorder ": 25.227542981438216, "Bladder obstruction ": 96.28437012166049, "Bladder pain ": 39.66649432765731, "Bladder spasm ": 46.27468605207611, "Blindness ": 2.255868560268788, "Blood urine present ": 6.4138136772640895, "Body height decreased ": 17.66579520163965, "Cataract ": 2.5011124588853395, "Cerebral disorder ": 3.632783778645541, "Cerebrovascular accident ": 2.4617214737178603, "Cognitive disorder ": 3.928432262636733, "Confusional state ": 2.160341801823328, "Constipation ": 6.035025213305628, "Cystitis ": 11.190037512622222, "Dementia ": 18.64045421702887, "Dementia Alzheimer's type ": 6.946127994218147, "Drug ineffective ": 2.0789506359057905, "Dry eye ": 10.75103012716396, "Dry mouth ": 21.3394156589005, "Dry throat ": 19.85959229979885, "Dysgraphia ": 6.4057347398106215, "Dysphagia ": 2.696459266231248, "Dysphonia ": 2.247012548641629, "Dysstasia ": 2.283923815862176, "Dysuria ": 27.516202212383007, "Eructation ": 3.4894684076972378, "Expired product administered ": 3.0213527704479746, "Extra dose administered ": 2.127016158423624, "Eye disorder ": 3.862410515655502, "Faecaloma ": 6.322670950683489, "Fall ": 2.7652926131467943, "Feeling abnormal ": 2.07285555392757, "Fluid retention ": 2.902403617672097, "Gait disturbance ": 2.5453545002188736, "Gingival pain ": 3.49278620452905, "Glaucoma ": 7.079840221839622, "Head injury ": 2.3192771840047235, "Hydronephrosis ": 6.592974148708766, "Hypertonic bladder ": 20.09643440232842, "Hypoacusis ": 4.832171904964978, "Hypotonic urinary bladder ": 167.9625798856184, "Ileus ": 3.5806682207386484, "Illness ": 2.291088240965124, "Implant site erosion ": 169.6004886034721, "Implant site infection ": 59.44726748539614, "Inappropriate antidiuretic hormone secretion ": 2.4605908820595768, "Incontinence ": 6.274686445724933, "Intentional product misuse ": 2.1827080823906493, "Intestinal obstruction ": 2.8572165296643317, "Intraocular pressure increased ": 4.718217787779083, "Joint injury ": 2.7403460407402047, "Kidney infection ": 3.9097138864339738, "Lip dry ": 7.053491848512653, "Lip swelling ": 2.36492739717607, "Memory impairment ": 3.3007688490311677, "Mental impairment ": 3.975150120917871, "Micturition disorder ": 16.291095437403083, "Micturition urgency ": 23.460789938807768, "Middle insomnia ": 5.353819996751486, "Mouth swelling ": 3.290525796172336, "Multiple sclerosis ": 6.419184797446486, "Muscle tightness ": 4.817108927544359, "Musculoskeletal disorder ": 8.347428426560988, "Nasal dryness ": 8.477493313926937, "Neoplasm malignant ": 2.416904902567219, "Nocturia ": 18.684595985090297, "Overweight ": 6.977681065854134, "Parkinson's disease ": 11.154932242831832, "Pelvic pain ": 4.3015003600387685, "Performance status decreased ": 6.270564642182218, "Pharyngeal swelling ": 2.2650142803064, "Pollakiuria ": 11.34076737873998, "Post micturition dribble ": 133.10271977977422, "Product dispensing error ": 5.17099796717938, "Product prescribing error ": 6.357167940172565, "Prostatic disorder ": 9.568910677146164, "Prostatomegaly ": 10.84742633209079, "Pyelonephritis ": 2.459373624519442, "Residual urine volume increased ": 467.9031164856961, "Road traffic accident ": 2.2744803416205794, "Sinus disorder ": 2.8776509727295245, "Speech disorder ": 2.191302984058232, "Spinal disorder ": 6.368500708687698, "Subileus ": 13.920481368522324, "Swollen tongue ": 2.633845946699353, "Therapeutic product effect incomplete ": 5.724249445277831, "Therapeutic response decreased ": 4.108954361501141, "Thirst ": 8.227023601584046, "Unevaluable event ": 2.53481196005712, "Urge incontinence ": 35.666869643098714, "Urinary hesitation ": 29.163745407333025, "Urinary incontinence ": 12.796172326019976, "Urinary retention ": 300.15280838641866, "Urinary tract disorder ": 13.922313747760397, "Urinary tract infection ": 5.819138300245455, "Urinary tract obstruction ": 24.78550128291997, "Urine abnormality ": 7.234271439301564, "Urine flow decreased ": 61.63556198322418, "Urine output decreased ": 2.961186779368628, "Vision blurred ": 4.571683440713003, "Weight bearing difficulty ": 8.776479087454058, "Weight fluctuation ": 7.170977782469854, "Wound dehiscence ": 28.50521307785547, "Wound drainage ": 169.6004886034721, "Wrist fracture ": 2.138625514083853, "Wrong technique in product usage process ": 2.1179398221122367}
\ No newline at end of file
+{"Arrhythmia": 7.027505058064821, "Atrial fibrillation": 24.6926801367687, "Drug interaction": 5.800276807716031, "Electrocardiogram QT prolonged": 10.489360458467567, "Heart rate decreased": 14.197114362627648, "Heart rate increased": 6.239990256040112, "Visual impairment": 3.519889071561064}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1088.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1088.json
index a6277978861..90eec9e5c37 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1088.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1088.json
@@ -1 +1 @@
-{"Acne cystic ": 2.484405858147312, "Acute macular neuroretinopathy ": 2.8015398764998665, "Adnexa uteri pain ": 2.0413758384240026, "Ageusia ": 2.041938635212197, "Allergy to arthropod bite ": 2.3827473865841333, "Allergy to vaccine ": 8.866918944504551, "Anosmia ": 2.807698796947334, "Anovulatory cycle ": 2.924659081092174, "Arthritis reactive ": 3.60862233528396, "Asthenopia ": 3.617422208224764, "Autoimmune arthritis ": 3.0927091769708768, "Autoimmune disorder ": 2.0335366139858992, "Autoscopy ": 2.832154469550382, "Axillary mass ": 6.908733209412334, "Axillary pain ": 5.699361494038049, "Bell's palsy ": 9.50709717231816, "Blue toe syndrome ": 3.6437677663766967, "Body temperature abnormal ": 2.791561788204352, "Body temperature fluctuation ": 2.6768418020425573, "Bone swelling ": 3.4615000751320717, "Brain fog ": 6.558693573849739, "Breast mass ": 2.4860751803810763, "Breast pain ": 2.886934704916904, "Breast swelling ": 3.076130311156124, "Burning sensation ": 2.0819961153917643, "COVID-19 ": 4.375221065870345, "COVID-19 pneumonia ": 2.033815460884681, "Cardiac flutter ": 11.27084955773214, "Cardiac infection ": 5.255332320011857, "Carditis ": 4.204783700666646, "Cerebellar stroke ": 2.072595285767506, "Cerebral thrombosis ": 2.5051525685060083, "Chest crushing ": 5.386129763745794, "Chest discomfort ": 2.0088912106510084, "Chest pain ": 2.7957070698528304, "Chillblains ": 2.8024288976666707, "Chronic fatigue syndrome ": 2.8100010526439, "Chronic spontaneous urticaria ": 2.149133624432197, "Cluster headache ": 4.667808309579085, "Cold sweat ": 2.56030530046274, "Cold-stimulus headache ": 3.4976507369395096, "Corneal graft rejection ": 3.267039356919863, "Corneal reflex decreased ": 2.372906676943211, "Costochondritis ": 5.898623459376499, "Deafness ": 2.3695526984571567, "Deafness unilateral ": 3.7042892082115353, "Dermatomyositis ": 2.04070475777544, "Disease recurrence ": 6.732052218943255, "Disseminated Bacillus Calmette-Guerin infection ": 9.151708164048562, "Dizziness exertional ": 3.270550566860888, "Dizziness postural ": 4.183841278010476, "Drug ineffective ": 2.1424111263730032, "Dysmenorrhoea ": 5.367182833756627, "Dysstasia ": 2.057555874985428, "Ear congestion ": 2.7542527040907827, "Ear discomfort ": 3.344943388244186, "Ear disorder ": 2.2504820504513874, "Ear pain ": 3.272634632194375, "Ear swelling ": 2.437675179067164, "Endocrine ophthalmopathy ": 2.5371080243434303, "Endometriosis ": 2.4706290351643827, "Enlarged uvula ": 3.5363422881975803, "Exposure to SARS-CoV-2 ": 5.366184087862226, "Eye injury ": 2.3620631618509718, "Eye pain ": 2.549512337552072, "Eye swelling ": 2.7993018908731995, "Eyelid pain ": 2.6037313011132275, "Eyelids pruritus ": 2.229524619315152, "Facial discomfort ": 3.7192464605949, "Facial pain ": 3.598902133497389, "Facial paralysis ": 3.2236443196355293, "Facial spasm ": 3.5375649423788067, "Feeling abnormal ": 2.276074056105211, "Feeling cold ": 2.218611518280556, "Feeling hot ": 2.1071363003896453, "Feeling of body temperature change ": 3.958156170853539, "Gingival blister ": 2.172656491762368, "Glomerulonephritis minimal lesion ": 4.63559820657885, "Guillain-Barre syndrome ": 2.418381236233508, "Hangover ": 3.37670128122167, "Head discomfort ": 2.496672838788029, "Heart rate ": 2.2292424886613262, "Heart rate abnormal ": 4.583729138405138, "Heart rate increased ": 2.596481050409661, "Heart rate irregular ": 2.479085418341368, "Heavy menstrual bleeding ": 4.188963628794524, "Hemiplegic migraine ": 6.413513610711707, "Hyperacusis ": 2.661869130258236, "Hypersomnia ": 2.322969365888668, "Hypoaesthesia ": 2.5408558399282644, "Hypoaesthesia eye ": 3.3728637076412324, "Hypoaesthesia oral ": 3.30126526007234, "Hypokinesia ": 2.4754429243777434, "Hypomenorrhoea ": 3.3028808954912683, "Hypopnoea ": 2.7796850447241885, "IVth nerve paralysis ": 2.636116327406363, "IgA nephropathy ": 2.412441890747129, "Illness ": 3.2213659858359653, "Immunisation ": 4.121053531969557, "Inappropriate schedule of product administration ": 7.140304059688646, "Induration ": 7.257153569451437, "Infant irritability ": 3.148713819821033, "Infantile vomiting ": 2.188421430891237, "Inflammation ": 2.6730328219809256, "Inner ear inflammation ": 4.801069340858438, "Joint lock ": 2.0736027756802224, "Joint noise ": 2.23429294556314, "Joint range of motion decreased ": 3.819706773869732, "Joint stiffness ": 2.0010797100397326, "Labyrinthitis ": 4.040149543526483, "Lack of spontaneous speech ": 3.983617823266553, "Latent autoimmune diabetes in adults ": 2.3827473865841333, "Lethargy ": 2.997497318288075, "Limb mass ": 3.268402775107524, "Lip swelling ": 2.179975985610524, "Lymph gland infection ": 5.808362723274055, "Lymph node pain ": 5.29085486112161, "Lymphadenopathy ": 2.488782440488037, "Mast cell activation syndrome ": 2.990434072403617, "Mastitis ": 4.257247956806352, "Maternal exposure during breast feeding ": 2.0632600349081938, "Menopause ": 3.084408508421559, "Menstruation delayed ": 4.0383497638216, "Menstruation irregular ": 3.537129160155573, "Mental fatigue ": 5.23567206909259, "Metamorphopsia ": 2.2876058947560405, "Migraine ": 3.1160555892674657, "Migraine with aura ": 4.006577048301333, "Miliaria ": 3.71973640993095, "Monoplegia ": 2.479415176496815, "Morning sickness ": 2.347396016751878, "Motion sickness ": 4.755861875191933, "Motor neurone disease ": 2.073115216548373, "Movement disorder ": 2.053993429868784, "Multisystem inflammatory syndrome ": 3.785060574616325, "Multisystem inflammatory syndrome in children ": 6.556008980763848, "Muscle fatigue ": 4.266169355697603, "Muscle swelling ": 2.781660004013172, "Muscle tightness ": 2.242854824519322, "Muscle twitching ": 2.218725770693595, "Musculoskeletal chest pain ": 2.2837707447358224, "Myelitis transverse ": 4.412448005852357, "Myocardial injury ": 2.3277096064839493, "Myocardial oedema ": 2.7071847014629493, "Myocarditis ": 4.348857025585666, "Myopericarditis ": 5.774145755946964, "Nasal congestion ": 2.1810211268010526, "Near death experience ": 3.80713718278302, "Neck mass ": 2.782362586763087, "Neck pain ": 3.566426484498621, "Nerve injury ": 2.569295941281553, "Neuralgia ": 2.138028816407344, "Neuralgic amyotrophy ": 2.087049116050822, "Neurogenic shock ": 5.124071134384604, "Nodule ": 3.397248769884536, "Noninfective encephalitis ": 3.3148466642566565, "Occipital neuralgia ": 3.0939438485057367, "Ocular vascular disorder ": 4.101983273283674, "Odynophagia ": 2.681374666284752, "Ophthalmic migraine ": 2.06410230311864, "Oral lichen planus ": 2.448894810026476, "Oropharyngeal blistering ": 2.387967351399433, "Oropharyngeal pain ": 3.360691560852413, "Oversensing ": 4.350231800153703, "Ovulation delayed ": 2.5818452495589224, "Ovulation disorder ": 2.0284966627441463, "Ovulation pain ": 2.7015098054646414, "Pain ": 2.266764295438391, "Pain in extremity ": 3.0667185005472817, "Pain in jaw ": 2.7480001493909283, "Painful respiration ": 3.160612064944142, "Palpitations ": 2.564994031952629, "Paraesthesia ": 2.0028237766459056, "Paraesthesia oral ": 2.6093444679716784, "Paralysis ": 2.6046575527240705, "Paranasal sinus discomfort ": 3.270418421584146, "Pelvic haemorrhage ": 6.114042540995697, "Periarthritis ": 4.139391435415851, "Pericarditis ": 2.7996479110268413, "Periorbital swelling ": 2.263773396195595, "Peripheral swelling ": 2.237638262342473, "Pernio-like erythema ": 9.715910758572596, "Persistent postural-perceptual dizziness ": 4.617190615780875, "Pharyngeal hypoaesthesia ": 3.50560238317168, "Pharyngeal mass ": 3.329602349681321, "Pharyngeal paraesthesia ": 2.3500726213227163, "Pharyngeal swelling ": 2.501904512951657, "Photophobia ": 2.357834303746854, "Photopsia ": 2.34194078334566, "Piloerection ": 2.019168231434914, "Pityriasis ": 3.260185664789124, "Pityriasis rosea ": 2.819630884438891, "Pleuritic pain ": 2.9537116144952367, "Polycystic ovarian syndrome ": 2.206474284552243, "Polymerase chain reaction positive ": 6.738791305197456, "Polymyalgia rheumatica ": 2.6178996896848004, "Postmenopausal haemorrhage ": 3.3506715388992125, "Postural orthostatic tachycardia syndrome ": 3.8601782300333074, "Premenstrual dysphoric disorder ": 6.287452566398694, "Premenstrual pain ": 3.871367820119668, "Premenstrual syndrome ": 2.5097851662107797, "Primary stabbing headache ": 2.2666109172251563, "Product administered at inappropriate site ": 2.2862823049536014, "Product temperature excursion issue ": 2.0407330818695844, "Pulmonary pain ": 2.744278707777292, "Pulmonary thrombosis ": 2.925177588176418, "Radiculitis brachial ": 4.149864651049464, "Respiratory distress ": 3.590384955898968, "Retinal migraine ": 7.01482029435367, "Retinal white dots syndrome ": 13.59624061295808, "Rhinorrhoea ": 3.172850183630211, "SARS-CoV-2 test positive ": 2.1600787663012286, "Scrotal pain ": 2.03600058623516, "Sensation of blood flow ": 2.2680398052527977, "Sensitive skin ": 18.084999044892168, "Sensory loss ": 2.1462962080410457, "Shoulder injury related to vaccine administration ": 4.459749573229168, "Sinus congestion ": 2.2032655566132475, "Sinus headache ": 5.47308492743202, "Sinus pain ": 3.991756899755904, "Sitting disability ": 2.602741907079197, "Skin warm ": 2.104937946707614, "Small fibre neuropathy ": 3.89974871465814, "Sneezing ": 2.4176557320064656, "Still's disease ": 2.2112284861137934, "Suspected COVID-19 ": 23.529649797459346, "Sweating fever ": 4.362207654457202, "Swelling ": 2.2537684987598663, "Swollen tongue ": 2.047366949116115, "Syncope ": 2.34793687396068, "Temperature difference of extremities ": 3.6979745886150166, "Tension headache ": 3.8627439195794806, "Throat tightness ": 2.93172380102366, "Thrombosis ": 2.6350367394032865, "Thunderclap headache ": 3.1082828765687265, "Thyroid pain ": 2.483859214895332, "Thyroiditis subacute ": 5.158215641936212, "Tinnitus ": 2.853490623374106, "Tonsillar hypertrophy ": 2.761019116234644, "Tunnel vision ": 3.363362977826567, "Upper respiratory tract congestion ": 3.521983355175164, "Urticaria chronic ": 2.124771531808137, "Vaccination error ": 29.072777087524948, "Vaccination site bruising ": 6.428050111348359, "Vaccination site cellulitis ": 7.717756207141136, "Vaccination site discolouration ": 2.868779132931291, "Vaccination site haemorrhage ": 7.229896800170886, "Vaccination site hypersensitivity ": 2.906856411826692, "Vaccination site hypoaesthesia ": 7.009088563103866, "Vaccination site infection ": 3.34489649773022, "Vaccination site joint movement impairment ": 3.7230479611713263, "Vaccination site mass ": 10.541851363776289, "Vaccination site movement impairment ": 2.71175575432915, "Vaccination site nodule ": 2.622805498291795, "Vaccination site pain ": 2.0383860176818103, "Vaccination site paraesthesia ": 2.4717160890073604, "Vaccination site rash ": 3.1303716699667103, "Vaccination site urticaria ": 3.875361716620084, "Vaccination site warmth ": 2.798519888614446, "Vaginal haemorrhage ": 2.968841611225828, "Vascular headache ": 2.4554467342957302, "Vertigo positional ": 2.162057360441903, "Vestibular migraine ": 6.930457399542347, "Vestibular neuronitis ": 2.062572706111652, "Viral pharyngitis ": 2.645689076482844, "Viral rash ": 2.640952684133594, "Visual snow syndrome ": 3.5446272312075773, "Vomiting projectile ": 2.3734938015381157, "Vulval haemorrhage ": 10.100763130343555, "Vulval ulceration ": 3.714884121069701}
\ No newline at end of file
+{"Acute kidney injury": 6.690969155934481, "Acute lymphocytic leukaemia recurrent": 213.7602463923735, "Cytokine release syndrome": 372.884739585333, "Diffuse large B-cell lymphoma": 116.7143615763726, "Disease progression": 5.537481926080544, "Disseminated intravascular coagulation": 38.38684237003344, "Encephalopathy": 28.856036376113, "Febrile neutropenia": 13.811249080970205, "Haemophagocytic lymphohistiocytosis": 61.20934212873309, "Hypotension": 4.229431892781308, "Hypoxia": 17.688184690083133, "Immune effector cell-associated neurotoxicity syndrome": 378.3965970313274, "Lymphopenia": 75.03930993327171, "Malignant neoplasm progression": 2.229553208403124, "Neurotoxicity": 33.45867697076864, "Neutropenia": 3.2784398908442096, "Neutrophil count decreased": 22.27787845533811, "Platelet count decreased": 5.951540828268608, "Sepsis": 4.639928608539302, "Tumour lysis syndrome": 45.50688407212719, "White blood cell count decreased": 12.273883794568777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1089.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1089.json
index 3dfa786eb26..5c4e08e2fc4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1089.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1089.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.6540066578012853, "Alanine aminotransferase increased ": 7.781080583349353, "Anaemia ": 7.232512751105886, "Asthenia ": 2.1408646200046126, "Disease progression ": 4.981324741267289, "Febrile neutropenia ": 10.616668020940304, "Hepatotoxicity ": 19.16477250008546, "Hypertransaminasaemia ": 61.68296180850008, "Leukopenia ": 6.014067022917677, "Neutropenia ": 19.825730184724065, "Off label use ": 2.111934115910729, "Pancytopenia ": 13.470615035928716, "Product use in unapproved indication ": 3.3695815129012514, "Rhabdomyolysis ": 36.30981724335528, "Thrombocytopenia ": 9.63781859041453, "Transaminases increased ": 26.37968066570296}
\ No newline at end of file
+{"Myelosuppression": 150.64707793241547, "Neutrophil count decreased": 47.262203783402434, "Off label use": 2.412504694615924, "Platelet count decreased": 25.45588638138306, "White blood cell count decreased": 40.15888725408857}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/109.json
index 92dd7828d0a..3a28763ee8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/109.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 83.77124325345295, "Agitation ": 7.903658225681238, "Anxiety ": 5.906182057917096, "Depression ": 3.504193887030684, "Drug interaction ": 6.009614643584133, "Drug withdrawal syndrome ": 20.446490172271535, "Electrocardiogram QT prolonged ": 253.63140734918252, "Hyperhidrosis ": 3.787697675690107, "Leukaemia recurrent ": 1480.678075625734, "Obsessive thoughts ": 438.63740015950617, "Tremor ": 3.801050519230832}
\ No newline at end of file
+{"Abdominal discomfort": 14.712822997565189, "Acanthosis": 3.689522338401433, "Adjustment disorder with depressed mood": 3.5715678642549387, "Adverse drug reaction": 4.650827003170269, "Adverse event": 3.333293201427815, "Alanine aminotransferase abnormal": 2.725643760105183, "Allergic oedema": 2.971970738754869, "Allergy to chemicals": 6.724946439195117, "Alopecia": 12.548428878675352, "Anaemia of chronic disease": 3.9938660172710536, "Anal abscess": 4.494375245486609, "Ankle deformity": 15.334681157993126, "Ankle operation": 2.4790265989066387, "Ankylosing spondylitis": 2.2825464578450743, "Anti-cyclic citrullinated peptide antibody": 2.7535716367113023, "Anti-cyclic citrullinated peptide antibody positive": 37.69398534216226, "Aortic bruit": 13.803198171361196, "Appetite disorder": 3.7238335482826463, "Arthritis": 2.6019215335975114, "Arthritis infective": 7.513257798899215, "Arthrodesis": 8.73143915907816, "Arthropathy": 25.815791582631608, "Aspartate aminotransferase": 2.4766110911144734, "Autoimmune disorder": 4.121786791602451, "Back injury": 5.941367738227746, "Basal cell carcinoma": 2.1385627358960533, "Benign neoplasm": 4.605848588112912, "Bladder operation": 2.812448869023186, "Blister": 5.228692936520289, "Blood cholesterol increased": 7.327541659709261, "Blood immunoglobulin A decreased": 2.179534045151754, "Blood immunoglobulin M increased": 2.2861795506924336, "Blood iron abnormal": 127.69870074374388, "Blood magnesium increased": 9.49072966429159, "Blood parathyroid hormone decreased": 7.521311168320196, "Blood pressure diastolic abnormal": 2.4242689196187177, "Blood pressure systolic abnormal": 2.373525014804533, "Bloody discharge": 3.166932900396348, "Bone cyst": 23.24772682672204, "Bone deformity": 2.63038578287804, "Bone erosion": 29.95906977558709, "Bone graft": 9.212857541672856, "Bone swelling": 11.271172217124418, "Breast cancer stage II": 2.0314576374037085, "Breast cancer stage III": 3.725098604859497, "Breast prosthesis user": 34.65503553345888, "Bunion operation": 55.159018252257326, "Bursitis": 4.767680964386109, "Bursitis infective": 6.592230742473302, "C-reactive protein": 11.95018163133427, "C-reactive protein abnormal": 19.300813727227176, "C-reactive protein decreased": 2.989873492007707, "C-reactive protein increased": 3.05632849431567, "Carbon dioxide abnormal": 15.24228403246938, "Carbon dioxide decreased": 4.879104536881315, "Chondropathy": 4.359068067073433, "Coeliac disease": 2.7828400475922743, "Colitis microscopic": 3.3629112183938026, "Condition aggravated": 3.7762196937261487, "Congenital anomaly": 11.89381855873356, "Contraindicated product administered": 32.500710094480844, "Contraindicated product prescribed": 3.0939379376819365, "Contraindication to vaccination": 4.170074981818623, "Contrast media allergy": 2.624500721923035, "Contusion": 3.2922468019153484, "Crepitations": 2.949820818335621, "Cytology abnormal": 9.794531187846172, "Deafness transitory": 11.2551172366589, "Deep vein thrombosis postoperative": 14.772536643103148, "Deformity": 4.822604890925761, "Dermatitis psoriasiform": 3.659225761321351, "Discomfort": 12.537080677640091, "Disease susceptibility": 4.002942031850453, "Dislocation of vertebra": 2.1452438417989543, "Drug hypersensitivity": 6.205711072290763, "Drug ineffective": 3.796879136494177, "Drug intolerance": 14.616084028582849, "Drug tolerance": 2.116436129477965, "Drug tolerance decreased": 22.939236379392327, "Duodenal ulcer perforation": 34.06516524957513, "Dysphoria": 2.3794933802617173, "Ear pain": 5.567009362341646, "Elbow deformity": 9.311106814813485, "Elbow operation": 6.080807169804451, "Encephalitis brain stem": 3.756943216475876, "Endocrine ophthalmopathy": 6.369799322648385, "Epigastric discomfort": 2.042677559216824, "Exostosis": 13.483474909926564, "Extremity contracture": 4.122586043687391, "Eyelid disorder": 2.780363366325544, "Facet joint syndrome": 7.414049638445824, "Fibromyalgia": 4.219781727824279, "Fine motor skill dysfunction": 5.1734118156314, "Finger deformity": 11.551486270046196, "Folliculitis": 13.901434437701106, "Foot deformity": 13.215359574165369, "Foot operation": 7.043362194191314, "Functional gastrointestinal disorder": 2.380394839153929, "Gait inability": 2.239598884668879, "Gastroenteritis salmonella": 2.3185940335131363, "Gastrointestinal disorder": 4.318883931143318, "Gastrointestinal toxicity": 11.267423015570712, "General physical health deterioration": 3.724033325652897, "Glossodynia": 47.29109702107069, "Granuloma skin": 9.64422837654782, "Granulomatous dermatitis": 4.924525643056774, "Grip strength decreased": 3.0948660475633982, "Haemodilution": 15.32828935423587, "Haemorrhagic diathesis": 4.0794453656895335, "Hand deformity": 57.71539517717878, "Helicobacter infection": 31.054017827995203, "Hepatic enzyme increased": 8.841905785139128, "Hepatic fibrosis": 2.2515013056776083, "Hepatic haematoma": 6.094136140217494, "Hepatic steatosis": 2.3329469870494544, "Hepatitis B core antibody positive": 4.632415713392016, "Hepatotoxicity": 2.7113411370450806, "Hip arthroplasty": 16.90481630074737, "Hip deformity": 4.39205658893626, "Histiocytosis": 11.067568365815692, "Hunger": 4.238352495309346, "Hypercholesterolaemia": 4.321216691001969, "Hypermobility syndrome": 6.647507794131284, "Hypersensitivity": 4.387694109081781, "Ill-defined disorder": 5.669298790650416, "Immobile": 4.210660357944211, "Impaired healing": 9.776188047234552, "Infection": 4.301705899750052, "Infusion related reaction": 14.730530878140348, "Intentional product use issue": 2.847885062246545, "Interferon gamma release assay positive": 16.75804935473935, "Intervertebral disc compression": 14.617628565949436, "Intervertebral disc space narrowing": 20.580049347749675, "Intestinal polyp": 3.0837490587515157, "Investigation abnormal": 5.911423412758685, "Irritable bowel syndrome": 7.768512523980321, "Joint ankylosis": 8.046227968647832, "Joint arthroplasty": 4.161411677282365, "Joint dislocation": 5.753669442414161, "Joint injury": 4.748670391265248, "Joint laxity": 5.151728547941032, "Joint lock": 3.154657351955785, "Joint range of motion decreased": 3.740493282261384, "Joint space narrowing": 3.845305753883379, "Joint stiffness": 6.916790874103257, "Joint surgery": 11.199492756394845, "Joint swelling": 14.2544577443333, "Keratitis": 2.089065802315085, "Kidney infection": 3.107925539824746, "Knee arthroplasty": 18.665674773479456, "Labile blood pressure": 2.1312807945210435, "Laryngeal disorder": 12.694111910741034, "Laryngitis": 2.9137068125697407, "Limb deformity": 8.839683254211137, "Limb operation": 2.578337883795712, "Lip ulceration": 3.5023443921986, "Live birth": 6.834211130611148, "Liver function test increased": 2.910246955834071, "Liver injury": 6.35755018940815, "Localised infection": 2.3168069611216326, "Loose body in joint": 4.246573894063476, "Loss of employment": 6.622499167719512, "Loss of personal independence in daily activities": 3.597941986946476, "Lower limb fracture": 2.57124616805886, "Lower respiratory tract infection": 8.20563566790455, "Lupus vulgaris": 2.1040153376664965, "Lupus-like syndrome": 2.1692449270027683, "Lymphocyte count increased": 2.905013977835381, "Maculopathy": 2.098789847042928, "Maternal exposure before pregnancy": 2.7943649284572616, "Maternal exposure during pregnancy": 10.60478319495532, "Mean cell haemoglobin increased": 6.954711107571752, "Medical device implantation": 2.9917569665789454, "Microcytic anaemia": 2.006933672393702, "Mobility decreased": 2.5668715421121515, "Morphoea": 2.966482432602408, "Multiple allergies": 2.30733063975026, "Muscle injury": 11.258889709866033, "Muscle spasticity": 21.03464030881036, "Musculoskeletal disorder": 5.051722287851697, "Musculoskeletal pain": 4.061322460784969, "Musculoskeletal stiffness": 6.168311247195339, "Mycobacterium tuberculosis complex test positive": 4.447759187357514, "Nail disorder": 2.6396429012077487, "Nail operation": 7.458798363398371, "Nasal ulcer": 6.7830602865765455, "Neck deformity": 17.007737406839695, "Nephrolithiasis": 2.431368560485615, "Nerve injury": 3.5035389997057163, "Night sweats": 4.958382937414924, "Non-Hodgkin's lymphoma": 5.497159063291184, "Ocular toxicity": 3.661593079593017, "Onycholysis": 3.859445458869238, "Osteoarthritis": 4.000919396590983, "Osteolysis": 5.403191692552197, "Osteosclerosis": 4.079463528497056, "Ovarian neoplasm": 3.824464016120521, "Pain": 3.2036279283833093, "Panniculitis": 2.2656017628602823, "Pemphigus": 98.9643399956502, "Pericarditis": 9.891106785388205, "Peripheral swelling": 2.9336385852086497, "Pleural fibrosis": 5.866058952718866, "Pleural thickening": 4.670245793891345, "Pneumonia cryptococcal": 2.830312972961501, "Pneumonia viral": 2.528489176556317, "Presbyacusis": 9.149477968100078, "Prescribed underdose": 3.558710354193266, "Product label confusion": 9.402919598981809, "Product use issue": 7.411716918120652, "Pruritus allergic": 2.8044765664138938, "Psoriatic arthropathy": 9.548573850052218, "Pulmonary congestion": 3.164521806788984, "Pulmonary fibrosis": 2.688794797124445, "Pulmonary mass": 2.499158986894849, "Pulmonary toxicity": 8.333437664968427, "Pustular psoriasis": 2.681353727273892, "Red blood cell sedimentation rate abnormal": 21.833924620604584, "Red blood cell sedimentation rate increased": 5.355240860022168, "Red cell distribution width increased": 2.0390502973786004, "Respiratory disorder": 6.309059389354301, "Respiratory tract congestion": 6.739397877362917, "Respiratory tract infection viral": 2.4297915697564094, "Rheumatic fever": 31.356341581121704, "Rheumatoid arthritis": 26.074845031587152, "Rheumatoid factor increased": 2.8822192279413748, "Rheumatoid factor negative": 54.05395257023845, "Rheumatoid factor positive": 57.67830202675936, "Rheumatoid lung": 7.327788556006872, "Rheumatoid nodule": 34.1196640099793, "Sciatica": 2.7755781579301644, "Sensitivity to weather change": 2.3424727231521256, "Seronegative arthritis": 7.056045226563335, "Shoulder arthroplasty": 4.293025136184615, "Sinusitis": 5.587179857308298, "Sjogren's syndrome": 4.287293736055015, "Skin ulcer": 2.360979881018753, "Skin warm": 2.8358556089888243, "Sleep disorder due to general medical condition, insomnia type": 6.351521446452278, "Soft tissue disorder": 8.01678529751211, "Soft tissue swelling": 5.492574302228622, "Stomatitis": 2.098312542233166, "Stress at work": 4.35427156831642, "Surgical failure": 4.603235090898995, "Swelling": 10.424559399904975, "Swollen joint count increased": 49.967261045310735, "Synovial cyst": 3.838625189221717, "Synovial disorder": 2.495508428723587, "Synovitis": 41.80176238718369, "Systemic lupus erythematosus": 50.23302882403277, "Systemic lupus erythematosus rash": 47.50555943343338, "Tenosynovitis": 7.702402313809332, "Therapeutic product effect decreased": 11.316867756933028, "Therapeutic product effect incomplete": 3.110579486270014, "Therapy non-responder": 2.251672470631204, "Thyroid neoplasm": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1090.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1090.json
index 8832bae4fd7..133f1086a4d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1090.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1090.json
@@ -1 +1 @@
-{"Abortion induced ": 6.086982017000009, "Acute respiratory distress syndrome ": 2.070060503098204, "Acute respiratory failure ": 6.624762921550798, "Alanine aminotransferase increased ": 16.617943678441424, "Ammonia increased ": 2.150567695161058, "Angioplasty ": 8.806714440816204, "Anuria ": 2.339000068891427, "Aortic stenosis ": 6.174466580238899, "Ascites ": 5.747668120628645, "Aspartate aminotransferase increased ": 18.86373775276574, "Atrial flutter ": 5.94304999987833, "Atrial septal defect repair ": 144.42100034513936, "Autoimmune hepatitis ": 3.228217651011847, "Bilirubin conjugated increased ": 12.174626518170689, "Biopsy liver ": 70.25801614930803, "Blood alkaline phosphatase increased ": 22.12681368373806, "Blood bilirubin increased ": 13.98380988349298, "Blood culture positive ": 19.469518111938108, "Blood iron decreased ": 2.378110733013505, "Blood potassium increased ": 2.131973845850877, "Brain natriuretic peptide increased ": 7.935174741042364, "Bronchitis ": 2.368802221145326, "Carbon dioxide increased ": 14.45324761587982, "Cardiac ablation ": 14.403070509007652, "Cardiac arrest ": 3.413382068506249, "Cardiac failure ": 7.173187375515088, "Cardiac failure acute ": 6.1118079827408085, "Cardiac failure chronic ": 4.221873232979084, "Cardiac failure congestive ": 4.858158043253091, "Cardiac operation ": 7.013534234440036, "Cardiac output decreased ": 15.925781071101683, "Cardiac pacemaker insertion ": 5.623846725932027, "Cardiac tamponade ": 2.36056650742856, "Cardio-respiratory arrest ": 2.4925442470817534, "Cardiopulmonary failure ": 11.494998527235657, "Cardioversion ": 5.413709178254137, "Catheter management ": 79.899170970412, "Catheter placement ": 28.57035584100068, "Catheter site discharge ": 45.369781943060254, "Catheter site erythema ": 45.78843151475421, "Catheter site haemorrhage ": 14.83711954210299, "Catheter site infection ": 38.86993871788317, "Catheter site pain ": 28.16796955420939, "Catheter site pruritus ": 18.204207325980374, "Catheter site swelling ": 54.724099387738335, "Catheterisation cardiac ": 19.746812608045573, "Central venous catheterisation ": 7.387664812756595, "Chemotherapy ": 8.63911813377018, "Cholecystectomy ": 3.436167055841836, "Cholelithiasis ": 2.0824844979410857, "Chronic obstructive pulmonary disease ": 3.4988913242046955, "Chronic respiratory failure ": 28.86776117167693, "Coagulation test abnormal ": 7.406670897859708, "Complication associated with device ": 15.85797292867412, "Concomitant disease aggravated ": 11.830409118923937, "Concomitant disease progression ": 7.660170385690843, "Condition aggravated ": 4.040791798761954, "Congestive hepatopathy ": 33.590721466936046, "Cor pulmonale ": 75.32183481054007, "Cyanosis ": 3.1986955306397427, "Death ": 10.7464331906387, "Device alarm issue ": 36.71919103493391, "Device breakage ": 8.127515255569795, "Device dislocation ": 7.139094717105061, "Device infusion issue ": 14.312000949565482, "Device leakage ": 12.499527746502226, "Device malfunction ": 2.356471818319452, "Device occlusion ": 11.960816242960972, "Device physical property issue ": 9.672664379727996, "Device related infection ": 10.561521861526485, "Device related sepsis ": 13.396763461393135, "Dialysis ": 7.093199902209117, "Disease complication ": 24.96451421504545, "Disease progression ": 6.610990059364696, "Dyspnoea ": 2.893974703636085, "Dyspnoea exertional ": 4.141406100953541, "Echocardiogram abnormal ": 8.83963864030103, "Endarterectomy ": 70.75848955340513, "Endocarditis ": 2.3131091085449773, "Endotracheal intubation ": 10.505880620412116, "Erysipelas ": 2.0635038695183754, "Exercise tolerance decreased ": 3.0743131068499108, "Failure to thrive ": 3.595594437885426, "Fluid retention ": 13.74204449800592, "Flushing ": 2.161731312289462, "Gamma-glutamyltransferase increased ": 8.540162960316653, "Gangrene ": 3.409082278858314, "Gastroenteritis viral ": 4.5318037632284405, "Gastrointestinal infection ": 2.727520721167108, "Gastrointestinal motility disorder ": 2.457210643549166, "Gastrointestinal tube insertion ": 7.879626722451301, "General physical condition abnormal ": 2.351162456505008, "Generalised oedema ": 3.744146053088675, "Haematocrit decreased ": 4.185402766710015, "Haemodynamic instability ": 2.7061258934387142, "Haemoglobin decreased ": 2.283445841864052, "Haemoptysis ": 5.124650840363503, "Heart and lung transplant ": 153.6498255998542, "Heart disease congenital ": 2.1924865879802984, "Heart transplant ": 44.40121679275831, "Hepatic cirrhosis ": 3.263835706207077, "Hepatic cytolysis ": 2.748228101769231, "Hepatic enzyme abnormal ": 3.5663816642106645, "Hepatic enzyme increased ": 2.367329622969917, "Hepatic failure ": 2.4393427003107444, "Hepatomegaly ": 3.3072012109477136, "Hip fracture ": 2.583591211890956, "Hip surgery ": 4.4099615264416165, "Hospitalisation ": 3.345196572229051, "Hypervolaemia ": 27.857632952953256, "Hypoxia ": 10.650307872178091, "Infusion site erythema ": 6.628843076772189, "Infusion site pain ": 5.363027835015031, "International normalised ratio decreased ": 4.734810183627554, "International normalised ratio increased ": 2.111860339399548, "Intestinal ischaemia ": 2.097674721476978, "Jaundice ": 2.7808980535423427, "Left ventricular failure ": 10.338111683798267, "Liver function test abnormal ": 26.956228721887456, "Liver function test increased ": 19.71060452045376, "Lung disorder ": 2.384226814777129, "Lung infiltration ": 2.5948201457208384, "Lung transplant ": 101.10920016670671, "Mechanical ventilation ": 16.09085387542, "Medical device change ": 47.81268563204908, "Mineral supplementation ": 43.14966987734736, "Multiple organ dysfunction syndrome ": 3.7653623141773607, "N-terminal prohormone brain natriuretic peptide increased ": 5.34967562309036, "Normal newborn ": 3.4407828708352364, "Ocular icterus ": 3.8830844366291073, "Oedema ": 4.875915566124861, "Oedema peripheral ": 4.762629962140861, "Orthopnoea ": 8.420093556048611, "Oxygen consumption increased ": 29.742254816213222, "Oxygen saturation abnormal ": 7.189704036274527, "Oxygen saturation decreased ": 6.225367342205363, "Oxygen therapy ": 5.5005768303592655, "Pain in jaw ": 4.122891400100203, "Paracentesis ": 31.727211363231174, "Pericardial effusion ": 4.794408175707647, "Platelet transfusion ": 11.800070091411234, "Pleural effusion ": 3.2224525026407527, "Pneumonia ": 3.926906343292319, "Pneumonia aspiration ": 2.1604316075228915, "Pneumonia viral ": 3.654001643077791, "Pneumothorax ": 3.285757160738092, "Post procedural complication ": 4.00504605451263, "Pregnancy ": 12.145529984146064, "Prothrombin time prolonged ": 2.5481573219932674, "Pulmonary arterial hypertension ": 140.41012890439302, "Pulmonary arterial pressure increased ": 34.96529188329854, "Pulmonary congestion ": 3.4119826193508467, "Pulmonary fibrosis ": 5.972027503145929, "Pulmonary haemorrhage ": 5.261708859275798, "Pulmonary hypertension ": 49.42326982649671, "Pulmonary hypertensive crisis ": 157.9687662366876, "Pulmonary oedema ": 5.329283667921053, "Pulmonary veno-occlusive disease ": 23.360554708260626, "Pulseless electrical activity ": 3.031727869409328, "Radiotherapy ": 5.300263592362989, "Raynaud's phenomenon ": 2.0397808543979017, "Red blood cell transfusion ": 16.84039354442232, "Respiratory distress ": 2.4865160126474946, "Respiratory failure ": 10.225034400103748, "Respiratory syncytial virus infection ": 2.4661660381695563, "Respiratory tract infection ": 4.215746945787666, "Respiratory tract infection viral ": 8.63540280505277, "Resuscitation ": 9.112999858904097, "Rhinovirus infection ": 11.829268524495577, "Right ventricular dysfunction ": 19.92864815176336, "Right ventricular failure ": 136.42799760721908, "Right-to-left cardiac shunt ": 242.0200617494706, "Sarcoidosis ": 2.1001413990118114, "Scleroderma ": 38.12374010520422, "Seasonal allergy ": 2.364734917583493, "Sepsis ": 3.7257839710867375, "Septic shock ": 2.370700903992396, "Skin ulcer ": 3.500765816671256, "Staphylococcal infection ": 2.826765265686747, "Staphylococcal sepsis ": 2.4191864465016697, "Sudden cardiac death ": 5.055599712276701, "Sudden death ": 6.911537933427729, "Supraventricular tachycardia ": 2.076142069136613, "Surgery ": 2.725809193865039, "Systemic scleroderma ": 35.71621698934188, "Terminal state ": 15.756491734455532, "Therapy change ": 3.9962170262754384, "Therapy non-responder ": 2.2861668064969507, "Tracheostomy ": 17.597883895440866, "Transaminases increased ": 2.8910366288048164, "Transfusion ": 17.948926901163937, "Transplant ": 15.042368387265812, "Transplant evaluation ": 52.327285995031495, "Tricuspid valve incompetence ": 3.259277291880033, "Unevaluable event ": 2.724870025667716, "Upper respiratory tract infection ": 2.6020171756417327, "Urine output decreased ": 2.5096190737698203, "Vascular device infection ": 28.89979877487792, "Viral infection ": 3.599241436131178, "Walking distance test abnormal ": 68.62983098871018}
\ No newline at end of file
+{"Abnormal dreams": 7.369999789464062, "Amnesia": 2.595667529497314, "Blood HIV RNA increased": 113.2947565518387, "Blood calcium increased": 10.782368581468528, "Blood creatine phosphokinase increased": 3.699981670724645, "Blood creatinine increased": 4.0523572205468845, "Cholestasis": 2.9158428083437973, "Deafness": 2.841806514409853, "Depressed mood": 3.033685811126822, "Depression": 2.839720441796729, "Dermatitis": 4.246830235609122, "Drug resistance": 3.075588478323166, "Dysuria": 3.0409831746805933, "Glomerular filtration rate decreased": 4.202684904602609, "Hepatic cytolysis": 2.5171205234106626, "Hepatic failure": 2.2570005405403166, "Hepatitis": 4.701953903118595, "Hospitalisation": 3.4045985499987865, "Hyperlipidaemia": 6.78991836222758, "Immune reconstitution inflammatory syndrome": 117.08157361621396, "Inhibitory drug interaction": 40.90244930920812, "Insomnia": 3.201936467142211, "Intervertebral disc disorder": 25.18928080442944, "Jaundice": 2.113807371817753, "Kaposi's sarcoma": 36.84762850203537, "Lactic acidosis": 2.584505602748674, "Lipodystrophy acquired": 16.553652358115084, "Liver function test abnormal": 2.8860344175572226, "Liver function test increased": 3.2125968792793502, "Lymphoma": 10.450593910608385, "Major depression": 16.01999119556906, "Mental disorder": 5.391991499208519, "Mycoplasma infection": 155.73506054310172, "Nephropathy": 3.4347291586537425, "Nervous system disorder": 4.602720773527096, "Nervousness": 2.4960177052602344, "Neurotoxicity": 23.15917344924086, "Nightmare": 5.080839812983594, "Osteopenia": 3.734166142319564, "Pancreatitis": 2.5533012752926343, "Pathogen resistance": 11.68661893294461, "Pneumocystis jirovecii pneumonia": 7.291528400449626, "Progressive multifocal leukoencephalopathy": 20.686411956313982, "Proteinuria": 2.5393731250062097, "Psychotic disorder": 2.9926273487737465, "Renal failure": 2.317494151286797, "Renal impairment": 3.805343784163744, "Sleep disorder": 3.6675845786876895, "Suicidal ideation": 6.1280402287620594, "Suicide attempt": 2.0921659789941742, "Transaminases increased": 3.536039119157437, "Treatment noncompliance": 6.366920213471998, "Tuberculosis": 12.91509444304382, "Upper-airway cough syndrome": 29.04998167215432, "Urethral discharge": 1037.6759625949808, "Urethritis": 120.02154130022788, "Viral load increased": 42.6312920656961, "Viral mutation identified": 23.3951337681442, "Virologic failure": 13.700562716154405, "Weight increased": 2.5727958342652557}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1091.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1091.json
index 82aefb54dfd..479b3d46c82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1091.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1091.json
@@ -1 +1 @@
-{"Acute pulmonary oedema ": 303.8077193865649, "Anaemia neonatal ": 1509.8887549805152, "Atrial septal defect ": 85.01316955297854, "Bradycardia foetal ": 236.24926298570804, "Bradycardia neonatal ": 536.6381484931023, "Cardiac failure ": 4.61775533056901, "Chest discomfort ": 2.403972557655992, "Dyspnoea ": 2.9025549773361257, "Exposure during pregnancy ": 7.37755324372561, "Foetal death ": 90.95769082566837, "Foetal exposure during pregnancy ": 20.554724924786896, "Foetal growth restriction ": 83.26589431194269, "Hypotension ": 3.930304973608624, "Hypoxia ": 15.243559350458913, "Inguinal hernia ": 71.60826009645038, "Jaundice ": 8.924990547457472, "Low birth weight baby ": 155.90377936877294, "Maternal exposure during pregnancy ": 6.326833517989214, "Overdose ": 3.1146338112295417, "Pericardial effusion ": 11.84002971292918, "Pleural effusion ": 10.504424069460146, "Premature baby ": 118.04908072199056, "Premature labour ": 55.9556496487921, "Product use in unapproved indication ": 2.1359791425450263, "Pulmonary hypertension ": 24.30728274357121, "Pulmonary oedema ": 44.54722180397435, "Respiratory distress ": 9.164597783782272, "Tachycardia ": 2.490921032690599}
\ No newline at end of file
+{"Bronchospasm": 71.21449624211903, "Chest discomfort": 8.083221560439734, "Condition aggravated": 2.514484175069501, "Cough": 12.825271405484347, "Cystic fibrosis": 706.7825124193597, "Death": 2.662542502907519, "Drug intolerance": 7.478322078284209, "Dyspnoea": 4.937724657453175, "Forced expiratory volume decreased": 189.36367883747508, "Haemoptysis": 72.22021283293803, "Infection": 4.371839808250974, "Lower respiratory tract infection": 10.94610738108935, "Oxygen saturation decreased": 12.153973291157918, "Pneumonia": 3.457184468562118, "Pulmonary function test decreased": 166.51235418965229, "Wheezing": 9.03421848054096}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1092.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1092.json
index d98a8788214..ff1e2c2c8c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1092.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1092.json
@@ -1 +1 @@
-{"Chest pain ": 5.392860257938281, "Hypoglycaemia ": 32.592981874841975}
\ No newline at end of file
+{"Acute kidney injury": 13.0797155076361, "Blindness": 3.5442191013587165, "Blood alkaline phosphatase increased": 2.270878993529436, "Blood creatinine increased": 6.760496047570615, "Blood pressure decreased": 2.054162149680281, "Blood urea increased": 11.694635508630489, "Bronchospasm": 9.03659129074215, "Clostridium difficile colitis": 7.330993510280246, "Colitis": 6.109173088166035, "Condition aggravated": 2.067618466170088, "Conjunctivitis": 4.69846648538013, "Corneal opacity": 50.27483862616008, "Creatinine renal clearance decreased": 25.58619062807742, "Cystic fibrosis": 77.28903628029178, "Deafness": 7.869634104270363, "Deafness neurosensory": 46.524488193918536, "Drug clearance decreased": 142.21029874448897, "Drug hypersensitivity": 4.071393377598039, "Drug ineffective": 2.300077532942089, "Drug level increased": 19.419871543939724, "Drug resistance": 9.636538525884005, "Eosinophil count abnormal": 74.65641238920456, "Eosinophilia": 4.763391445780803, "Eye pain": 3.4165936959212977, "Eye swelling": 3.379485528471644, "Eyelid oedema": 5.160497237279721, "Graft versus host disease": 10.042811175242203, "Haemoptysis": 2.673796057072801, "Hypoacusis": 5.693827936897788, "Hypopyon": 63.85817046197631, "Hypotension": 2.7267324954899648, "Incorrect route of product administration": 3.3041985821778623, "Infection": 2.1847065729397137, "Keratitis": 51.800995212431694, "Lactic acidosis": 2.488585383059465, "Leukocytosis": 5.886981850906022, "Lung disorder": 2.7022443059056065, "Multiple organ dysfunction syndrome": 3.664853757759001, "Nephrolithiasis": 2.80935944168595, "Nephropathy toxic": 15.63470794955351, "Ocular hyperaemia": 6.195404658368457, "Ototoxicity": 174.24190923011594, "Pathogen resistance": 45.98290959042277, "Pneumonia pseudomonal": 53.40531967015604, "Productive cough": 2.4334306499190306, "Pseudomembranous colitis": 46.61018151627578, "Pseudomonas infection": 51.875778004570485, "Pulmonary hypertension": 4.374604381434981, "Renal impairment": 4.570455530843854, "Renal tubular necrosis": 76.80143955603143, "Respiratory disorder": 5.513658245695871, "Respiratory rate decreased": 25.097384826881523, "Sepsis": 2.9687810000304475, "Septic shock": 6.001593484832365, "Staphylococcal infection": 6.208773911674653, "Therapy non-responder": 3.680238891399501, "Tinnitus": 3.927624229707052, "Toxic anterior segment syndrome": 55.38051686224862, "Toxic epidermal necrolysis": 8.230342361227871, "Ulcerative keratitis": 48.27170811765266, "Visual acuity reduced": 5.19426476495989, "White blood cell count increased": 4.033757670819093}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1093.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1093.json
index 60ac6bb919d..a29657eb76c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1093.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1093.json
@@ -1 +1 @@
-{"Alopecia ": 2.6241823660695704, "Dermatitis ": 18.485370912065417, "Dermatitis acneiform ": 178.3444788149086, "Disease progression ": 5.1633589549275785, "Dry skin ": 11.59659415397186, "Ejection fraction decreased ": 25.74398628167961, "Folliculitis ": 13.794110190105965, "Malignant neoplasm progression ": 25.4187534355958, "Metastatic malignant melanoma ": 432.5070243040728, "Paronychia ": 142.97919276519008, "Product use in unapproved indication ": 30.55299475881628, "Product use issue ": 12.723801347784429, "Rash ": 5.143628925197411, "Skin toxicity ": 61.042707162760856, "Therapeutic response decreased ": 8.513841285544412}
\ No newline at end of file
+{"Alanine aminotransferase increased": 2.0172808890689065, "Anaphylactic reaction": 3.164534656186301, "Arthritis": 4.69499557032757, "C-reactive protein increased": 2.434265704528589, "COVID-19 pneumonia": 7.925769766432829, "Cellulitis": 7.713518262586139, "Cytokine release syndrome": 4.830400873570399, "Diverticular perforation": 52.77297589269919, "Diverticulitis": 11.347052098873828, "Empyema": 56.00855925329524, "Haemophagocytic lymphohistiocytosis": 25.402921322524023, "Hepatic cytolysis": 2.2643063731999864, "Hepatitis": 6.4978951201722825, "Hypercholesterolaemia": 6.720206429157618, "Hypofibrinogenaemia": 615.9541135263365, "Hypoxia": 2.7969664028417323, "Infusion related reaction": 2.570380391443917, "Intentional product use issue": 19.649817627527007, "Intestinal perforation": 23.42307101439506, "Large intestine perforation": 34.58447319617437, "Leukopenia": 3.9260586029074656, "Neutropenia": 5.597620477429436, "Neutrophil count decreased": 2.149915894533707, "No adverse event": 5.226024175090145, "Off label use": 7.587236413145976, "Organising pneumonia": 15.905661834756629, "Pancreatitis acute": 2.2247782265943603, "Pneumonia": 2.177824187600497, "Product use in unapproved indication": 2.3852946371372146, "Respiratory failure": 2.244455095856854, "Sepsis": 4.303909252049593, "Septic shock": 5.78830968909358, "Staphylococcal infection": 3.916458845628713, "Therapy non-responder": 2.252527806287928, "Transaminases increased": 4.725558606344496, "Urinary tract infection": 2.039079977908542, "Vasculitis": 5.832308353963918}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1094.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1094.json
index a5a7efa64d9..7ba6afcd7b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1094.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1094.json
@@ -1 +1 @@
-{"Anaemia ": 2.9445581244438443, "Cardiac dysfunction ": 388.6841683303037, "Cardiac failure ": 7.603893313608792, "Cardiomyopathy ": 49.084121584695424, "Cardiotoxicity ": 131.50693862250031, "Constipation ": 2.3474564387636314, "Ejection fraction decreased ": 48.92501618829007, "Enterocolitis ": 65.77153017306227, "Febrile neutropenia ": 26.77580130996868, "Interstitial lung disease ": 3.606164845095734, "Malignant neoplasm progression ": 2.757867358889308, "Myelosuppression ": 23.164410871560133, "Neutropenia ": 9.678950034694838, "Neutrophil count decreased ": 7.749758097102998, "Septic shock ": 13.413268875353484, "White blood cell count decreased ": 4.2711855442322015}
\ No newline at end of file
+{"Blood creatinine increased": 6.501998249629692, "Eczema": 15.21187802587053, "Erythema": 3.3371425940926973, "Swelling": 4.8010335575525485}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1095.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1095.json
index a390229c6c8..fad3ec21c94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1095.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1095.json
@@ -1 +1 @@
-{"Cardiac arrest ": 31.970430033842455, "Completed suicide ": 72.86622490574653, "Respiratory arrest ": 91.75444738262584}
\ No newline at end of file
+{"Condition aggravated": 3.109116022126352, "Cytomegalovirus infection reactivation": 67.43635724112387, "Deep vein thrombosis": 5.057627676767332, "Herpes zoster": 3.9688817048490073, "Joint swelling": 4.312288669455672, "Off label use": 2.2870686361376205, "Pulmonary embolism": 5.458139007201937, "Rheumatoid arthritis": 4.11645173799976, "Treatment failure": 11.94247258971962}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1096.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1096.json
index a99199553cf..0844c0356a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1096.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1096.json
@@ -1 +1 @@
-{"Myalgia ": 5.535939184449084}
\ No newline at end of file
+{"Cough": 8.733516326598384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1097.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1097.json
index d2b26adc845..5624d4e14e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1097.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1097.json
@@ -1 +1 @@
-{"Accident ": 4.670951309476404, "Aneurysm ": 5.567259546844954, "Angina unstable ": 3.223128884475833, "Aphonia ": 8.244451803193433, "Aspiration ": 2.744863917268729, "Asthma ": 3.352290362705897, "Atrial fibrillation ": 3.1702367924003254, "Atrioventricular block ": 2.5449357182901884, "Bacterial infection ": 2.511012727946337, "Bladder cancer ": 2.6410840435154865, "Bladder disorder ": 3.568153805319373, "Blindness ": 2.049466158192442, "Blindness transient ": 3.109983849750288, "Brain neoplasm ": 3.2777683757849188, "Brain neoplasm malignant ": 13.736320069766396, "Bronchiectasis ": 3.840513859991636, "Bronchitis ": 5.042637806137165, "COVID-19 pneumonia ": 3.840290288463296, "Candida infection ": 8.759061066066417, "Cardiac disorder ": 3.343008967766028, "Cardiac failure congestive ": 3.1150042677692182, "Cardiac flutter ": 2.6704896872507438, "Cardiac operation ": 11.459746273228568, "Cardiac pacemaker insertion ": 8.639498293114581, "Cataract ": 4.940883649821618, "Cataract operation ": 6.5900996954939774, "Catheterisation cardiac ": 6.094726808339167, "Cerebrovascular accident ": 3.22997959908206, "Chemotherapy ": 8.961101107335706, "Choking ": 26.503436948744728, "Cholecystectomy ": 2.3292011040556155, "Chronic obstructive pulmonary disease ": 43.05834320283177, "Coccidioidomycosis ": 38.8707339963184, "Colon cancer ": 2.0937096326560045, "Condition aggravated ": 3.3019897589658624, "Coronary arterial stent insertion ": 11.870127098536482, "Coronavirus infection ": 11.163662834070758, "Coronavirus test positive ": 30.455702664025164, "Cough ": 5.048425573226026, "Death ": 9.091756758002507, "Dementia ": 3.376334451317821, "Dementia Alzheimer's type ": 2.3450147402492263, "Device use error ": 15.654731615164293, "Diabetes mellitus ": 2.3371442802411524, "Disability ": 3.371868173159086, "Disease complication ": 12.64212047139312, "Dry throat ": 4.2910741247371895, "Dysphonia ": 9.226007027080628, "Dyspnoea ": 4.870883233537683, "Dyspnoea exertional ": 3.556854458016285, "Dysuria ": 4.93417477080913, "Emphysema ": 15.793052976067624, "Endotracheal intubation ": 3.0459803455103094, "Extra dose administered ": 8.902964480715895, "Eye haemorrhage ": 3.280575214961225, "Fall ": 2.9116597196360754, "Foreign body in throat ": 33.04145542965983, "Frustration tolerance decreased ": 2.3497400465445595, "Fungal infection ": 2.0501469210395187, "Fungal pharyngitis ": 86.85027910110327, "Glaucoma ": 7.702344851887075, "Haemoptysis ": 2.563683852407619, "Heart valve replacement ": 14.043620342282749, "Hernia repair ": 14.37929895394199, "Hip arthroplasty ": 3.281440012979272, "Hip fracture ": 8.816957661870658, "Hip surgery ": 7.263830844368628, "Hospice care ": 13.544169009590073, "Hospitalisation ": 13.747641254992166, "Ill-defined disorder ": 3.443456257020577, "Illness ": 3.4542163024751527, "Inability to afford medication ": 30.973314589837297, "Incorrect dose administered ": 3.798670078725134, "Increased bronchial secretion ": 9.787910372809533, "Intentional dose omission ": 3.67426828525032, "Internal haemorrhage ": 3.2368065936582027, "Intraocular pressure increased ": 3.964608765707332, "Knee arthroplasty ": 2.0570595442127053, "Knee operation ": 6.974465800337878, "Labelled drug-disease interaction medication error ": 12.207265587748717, "Labelled drug-drug interaction medication error ": 5.71441106082268, "Laryngitis ": 2.5631663175555377, "Lip blister ": 6.989093735581003, "Localised infection ": 2.81792730857228, "Lower limb fracture ": 3.284768550631055, "Lower respiratory tract infection ": 5.433508115296665, "Lung carcinoma cell type unspecified stage IV ": 39.87834538346229, "Lung disorder ": 7.440279740818217, "Lung lobectomy ": 43.811456910452456, "Lung neoplasm malignant ": 27.365924611141427, "Lung operation ": 22.901769912136853, "Macular degeneration ": 2.61291106203906, "Micturition disorder ": 5.216566251678753, "Mouth ulceration ": 2.396665829430584, "Mycobacterium avium complex infection ": 9.264988059016911, "Myocardial infarction ": 3.237701485151042, "Near death experience ": 11.41260392557306, "Neoplasm malignant ": 6.841751279746122, "Oesophageal candidiasis ": 7.981816764431218, "Oral candidiasis ": 7.311876537172459, "Oral discomfort ": 3.477395642316657, "Oral fungal infection ": 6.13038502662616, "Oral pain ": 2.4985562764383187, "Oropharyngeal candidiasis ": 28.255059502047967, "Oropharyngeal discomfort ": 3.768375908403298, "Oxygen saturation abnormal ": 7.57887493788218, "Oxygen saturation decreased ": 5.1563944749702895, "Oxygen therapy ": 32.796794120896024, "Pelvic fracture ": 2.8037332454507453, "Pneumonectomy ": 99.3643285834608, "Pneumonia ": 14.009636760514418, "Pneumonia bacterial ": 4.494246955082044, "Pneumonia fungal ": 4.620909959577586, "Pneumothorax ": 8.334015459512946, "Post procedural complication ": 2.383922209404938, "Prescription drug used without a prescription ": 10.09147209738475, "Product after taste ": 18.5683780387856, "Product complaint ": 20.816183665126744, "Product dispensing error ": 4.224463027910352, "Product dose omission in error ": 4.525542566580455, "Product dose omission issue ": 9.28292667857046, "Product prescribing issue ": 9.139149993361707, "Product residue present ": 2.6255185714169857, "Product use in unapproved indication ": 3.643921820971313, "Product use issue ": 2.0577589425319247, "Product used for unknown indication ": 24.476145220105938, "Productive cough ": 12.065951279697362, "Prostate cancer ": 2.602796143928521, "Pseudomonas infection ": 3.29997373638286, "Pulmonary congestion ": 12.505475988850742, "Pulmonary fibrosis ": 2.3508006099854293, "Pulmonary function test decreased ": 5.028492387276258, "Pulmonary mass ": 6.805215879296961, "Pulmonary oedema ": 2.6999500823917546, "Pulmonary pain ": 3.9332992533586766, "Pulmonary thrombosis ": 2.34040032383598, "Rehabilitation therapy ": 30.6047325722367, "Respiration abnormal ": 2.2666545938746228, "Respiratory disorder ": 2.1570514190578893, "Respiratory failure ": 2.5871133600211333, "Respiratory tract congestion ": 4.065865544537248, "Respiratory tract infection ": 2.37920405180024, "Retching ": 2.398514662604955, "Rhinorrhoea ": 2.118557120821474, "Rib fracture ": 3.3974485563779275, "Secretion discharge ": 11.239389947321664, "Sinus congestion ": 2.5131455547262185, "Sinus disorder ": 3.6608284192976015, "Sleep disorder due to a general medical condition ": 3.219309590002695, "Small cell lung cancer ": 10.906994696250909, "Snoring ": 4.02587100078112, "Spinal fracture ": 6.002283675855728, "Spinal operation ": 2.4138276100422136, "Sputum discoloured ": 4.376865578213933, "Sputum increased ": 9.00064728229549, "Stent placement ": 9.643797786020706, "Surgery ": 5.103443256065959, "Terminal state ": 5.339048304557634, "Therapeutic product effect incomplete ": 2.86948186704888, "Therapy cessation ": 11.31408915890956, "Therapy interrupted ": 5.817377346601875, "Throat cancer ": 12.650415936596234, "Throat irritation ": 4.503511362282564, "Tongue blistering ": 5.707818731135406, "Tongue coated ": 5.263065139038861, "Treatment noncompliance ": 2.786538690936756, "Underdose ": 3.1445070133208906, "Upper-airway cough syndrome ": 3.5245183659369674, "Urinary retention ": 13.438931603965022, "Urinary tract disorder ": 5.0122756464477325, "Urine flow decreased ": 12.112919602068256, "Uterine cancer ": 3.3438686214612376, "Viral infection ": 2.9469089194913227, "Vision blurred ": 2.6769159722382745, "Wheezing ": 4.442134593427112, "Wrong technique in device usage process ": 69.05598797501257, "Wrong technique in product usage process ": 2.314015666238832}
\ No newline at end of file
+{"Blood pressure decreased": 12.857532436317255, "Cardiac failure": 10.879082301466296, "Drug ineffective": 2.052229026036925, "Drug interaction": 6.088677632461509, "Hypernatraemia": 175.80328272586783, "Product use in unapproved indication": 6.177040615773423, "Renal impairment": 8.282371217185235, "Sepsis": 10.057500191384774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1098.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1098.json
index be5f13e53b6..80adcd91ec1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1098.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1098.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.4410437219236285, "Abscess ": 2.2448150483924554, "Accidental exposure to product ": 58.70039904379816, "Ankylosing spondylitis ": 2.7764047075032097, "Arthritis ": 3.662403435132727, "Autoimmune thyroiditis ": 3.512658247908428, "Basal cell carcinoma ": 2.1642882776144337, "Brain injury ": 2.195912279431759, "Breast cancer ": 3.5062825348249373, "Bronchitis ": 2.7072940151323417, "COVID-19 pneumonia ": 3.3009901560394868, "Cardiac operation ": 4.7150718345661184, "Carpal tunnel syndrome ": 2.3581734268940098, "Cellulitis ": 6.41401529466631, "Cholecystectomy ": 4.808186939785323, "Colon cancer ": 2.487722162232629, "Cutaneous T-cell lymphoma ": 16.96927548812026, "Cystitis ": 2.2070660582060686, "Decreased immune responsiveness ": 4.471403261441751, "Dermatitis atopic ": 4.441265260678442, "Dermatitis exfoliative generalised ": 2.199418167848877, "Device defective ": 14.985216532288833, "Device deployment issue ": 86.11089488814868, "Device issue ": 55.77075548891202, "Device leakage ": 45.16790059742297, "Device malfunction ": 24.72326713500384, "Device occlusion ": 11.79705175260848, "Disability ": 3.3556239053043524, "Diverticulitis ": 3.6364452747953537, "Drug delivery system malfunction ": 45.04534043535944, "Eczema ": 3.8311504971157206, "Eczema nummular ": 29.83019089403181, "Endometrial cancer ": 25.99874083376843, "Erectile dysfunction ": 4.588913489690294, "Erythrodermic psoriasis ": 25.11654507779735, "Exposure during pregnancy ": 2.036631118603893, "Gamma-glutamyltransferase increased ": 2.576962333714977, "Gastric cancer ": 2.30277336883202, "Gastroenteritis ": 2.77382100238822, "Gout ": 2.410819836612428, "Guttate psoriasis ": 30.66734502213607, "Hepatic cirrhosis ": 2.213911939508271, "Hepatitis B ": 5.033579434180123, "Hernia ": 4.0896738319595, "Herpes virus infection ": 4.535238015381255, "Hip surgery ": 11.315971226143631, "Hodgkin's disease ": 10.788756280911102, "Hyperkeratosis ": 4.680934748073876, "Hysterectomy ": 6.457031983092547, "Inappropriate schedule of product administration ": 3.3051573197221056, "Incorrect route of product administration ": 2.45250134069794, "Infection ": 2.3025082836873763, "Injection site haemorrhage ": 10.530192868855435, "Injection site induration ": 2.6828618188839246, "Injection site mass ": 2.5563633257861187, "Injection site oedema ": 4.774647588402623, "Injection site pruritus ": 2.067079118421328, "Injection site rash ": 2.190674353365404, "Injection site reaction ": 3.0772059698816028, "Injection site urticaria ": 8.704523241469824, "Kidney infection ": 4.622606967974088, "Knee arthroplasty ": 6.179317218656493, "Knee operation ": 5.680464071656886, "Latent tuberculosis ": 22.44772158518783, "Liquid product physical issue ": 11.521932700711902, "Liver function test abnormal ": 5.194483329246184, "Loss of therapeutic response ": 53.96576756411759, "Lymphopenia ": 2.0438324511174466, "Malignant melanoma ": 3.0973226128390805, "Multiple sclerosis ": 2.0713916861042163, "Mycobacterium tuberculosis complex test positive ": 43.98230610947639, "Nail psoriasis ": 93.2330366114683, "Needle issue ": 73.62159192129377, "Nephrolithiasis ": 4.388197486484241, "Off label use ": 2.460537184395099, "Overweight ": 6.10867273416731, "Paternal exposure during pregnancy ": 58.39221289374553, "Pemphigoid ": 4.184461479573158, "Pneumonia bacterial ": 5.5982555188163206, "Post procedural complication ": 4.92119354707447, "Pregnancy of partner ": 96.61903333126422, "Procedural complication ": 16.049641240564625, "Product availability issue ": 7.886806890861887, "Product complaint ": 3.3616390902896325, "Product dose omission issue ": 25.50005196601781, "Product label issue ": 23.86849139802609, "Product leakage ": 74.06748461655228, "Product quality issue ": 9.74433628234364, "Product storage error ": 9.955614743636051, "Product use issue ": 2.857008505851736, "Prostate cancer ": 5.868992708556217, "Psoriasis ": 56.59738025111589, "Psoriasis area severity index increased ": 113.34041673486207, "Psoriatic arthropathy ": 95.32419704938978, "Pulmonary tuberculosis ": 6.425285551667952, "Pustular psoriasis ": 30.307479687933043, "Pustule ": 2.655966780777625, "Respiratory tract infection ": 4.388729838912569, "SARS-CoV-2 test positive ": 2.4737381089235084, "Self-medication ": 14.05492615559688, "Skin cancer ": 4.76401523562448, "Skin disorder ": 2.0899028626370044, "Skin exfoliation ": 2.741272450974, "Skin haemorrhage ": 3.1937057501170965, "Skin lesion ": 2.087699310849314, "Skin plaque ": 5.009690559137988, "Spinal operation ": 10.558274933026576, "Squamous cell carcinoma of skin ": 5.696122482542955, "Staphylococcal infection ": 2.6621656295759712, "Surgery ": 3.432819823791506, "Syringe issue ": 36.81146975776439, "Therapeutic product effect decreased ": 2.918241430140565, "Therapeutic response decreased ": 6.795064437110409, "Therapeutic response unexpected ": 4.6280133893951465, "Therapy cessation ": 17.130609920452333, "Therapy interrupted ": 4.060989595887197, "Therapy non-responder ": 2.1615537409863186, "Toothache ": 2.585514586382922, "Treatment noncompliance ": 2.5106829448185186, "Tuberculosis ": 10.618850494967962, "Underdose ": 18.58864933367332, "Upper respiratory tract infection ": 4.530205566613515, "Uterine cancer ": 6.1678790483861725}
\ No newline at end of file
+{"Anaemia": 6.872565164657599, "Anaplastic lymphoma kinase gene mutation": 1333.8882349122905, "Blood bilirubin increased": 4.701416267631148, "Bronchospasm": 42.62914140024444, "Choroidal dystrophy": 3234.0518187156263, "Cytopenia": 12.521510765777316, "Disease progression": 2.751038524122217, "Disease recurrence": 10.205481727110444, "Eyelid oedema": 23.55041516799586, "Eyelid ptosis": 32.60504106935826, "Febrile neutropenia": 80.62188377634364, "Haematotoxicity": 14.682500968407506, "Haematuria": 2.766400653094257, "Haemoglobin decreased": 2.9813532911053526, "Interstitial lung disease": 2.446565015257592, "Leukopenia": 6.148502679570859, "Lymphocyte count decreased": 8.37237025275072, "Madarosis": 111.006133198286, "Malignant neoplasm progression": 6.125014988030871, "Mucosal inflammation": 10.095124714877947, "Myelosuppression": 11.273516311575714, "Neoplasm progression": 4.272878503168244, "Neuroblastoma": 528.8684434796431, "Neutropenia": 17.17171221252555, "Neutrophil count decreased": 8.934665079638322, "Off label use": 2.005048063865786, "Pancytopenia": 14.640763910154396, "Platelet count decreased": 6.026869172562522, "Product use in unapproved indication": 6.38961981083039, "Product use issue": 4.312006486974255, "Red blood cell count decreased": 8.22848145155893, "Respiratory failure": 2.036617416230893, "Retinal vascular occlusion": 66.39421643281551, "Retinoblastoma": 3095.191333454762, "Small cell lung cancer": 69.52729451348233, "Stomatitis": 2.4378322198150792, "Thrombocytopenia": 9.148594050698737, "Treatment failure": 6.504851253767202, "Upper respiratory tract infection": 5.248301833835703, "Vascular occlusion": 44.88639736293338, "Vitreous haemorrhage": 50.29457033338881, "White blood cell count decreased": 8.70243420292299}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1099.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1099.json
index a0d3470997c..4b9d9fb95c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1099.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1099.json
@@ -1 +1 @@
-{"Off label use ": 4.8290121790433655, "Product use in unapproved indication ": 11.808888804047996}
\ No newline at end of file
+{"Acute kidney injury": 2.905409084821205, "Acute respiratory failure": 3.3555354295531385, "Anaemia": 2.98562578075412, "Angioedema": 2.593441455580831, "Aphthous ulcer": 9.09863849925276, "Ascites": 3.935584745180045, "Blood alkaline phosphatase increased": 3.923368540893705, "Blood creatinine increased": 7.317667885973548, "Blood lactate dehydrogenase increased": 2.6574965554513503, "Blood triglycerides increased": 13.50879310967688, "Blood urea increased": 4.145565248902495, "C-reactive protein increased": 2.218480462493136, "Cerebral haemorrhage": 2.760483759069148, "Death": 4.208830709779996, "Dehydration": 2.0035769897924154, "Diabetes mellitus": 3.2700989986205378, "Disease progression": 32.27406788403763, "Extravasation": 12.820160625412464, "Febrile neutropenia": 2.395941843603665, "Flushing": 5.590008523980762, "General physical health deterioration": 3.765928004252657, "Haemoptysis": 2.4054583742737488, "Hypercalcaemia": 3.94342967994974, "Hyperglycaemia": 3.779807369931933, "Hyperkalaemia": 2.121902355963867, "Hyperlipidaemia": 4.02508443267051, "Hypersensitivity": 2.250187994703694, "Hypertriglyceridaemia": 11.689391749696656, "Infusion related reaction": 4.113035691601546, "Interstitial lung disease": 25.40951788744201, "Intestinal perforation": 9.980368857218483, "Lung disorder": 2.6034988999078728, "Lung infiltration": 20.929469791936743, "Mantle cell lymphoma": 140.79980342004131, "Metastatic renal cell carcinoma": 46.4807089170371, "Microcytic anaemia": 34.65440871462857, "Mucosal inflammation": 8.135266549182274, "Nail disorder": 17.982508451786252, "Neoplasm malignant": 4.114377887002928, "Neoplasm progression": 14.6171425037178, "Oedema peripheral": 2.1490396980889046, "Oral pain": 3.0025155885227512, "Oxygen saturation decreased": 2.470567188539825, "Pancytopenia": 2.0059226652056497, "Pericardial effusion": 3.248567297118669, "Peritonitis": 5.153673278473041, "Platelet count decreased": 4.159827025248079, "Pleural effusion": 9.44044238726802, "Pneumocystis jirovecii pneumonia": 23.487759819321926, "Pneumonia": 2.5242735933770377, "Pneumonitis": 17.297661059169375, "Product use in unapproved indication": 2.552420577091, "Pulmonary fibrosis": 3.1487357653292696, "Pulmonary oedema": 2.302386819844626, "Renal cancer": 11.200809613314249, "Renal cancer metastatic": 55.3993001874512, "Renal cell carcinoma": 84.2343429833472, "Renal failure": 3.3586739360783544, "Stomatitis": 6.7169809363216375, "Thrombocytopenia": 3.050411755521342}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/11.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/11.json
index 01bce6894b8..821ebb2f02c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/11.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/11.json
@@ -1 +1 @@
-{"Deafness ": 57.3306409342533, "Disease progression ": 55.143023382756525, "Lymphadenopathy ": 5.855002439232344, "Mantle cell lymphoma recurrent ": 4869.774588526102, "Off label use ": 6.148326864036193}
\ No newline at end of file
+{"Anaemia": 3.221139019553731, "Ascites": 10.14915246132696, "Bone disorder": 10.893484085997594, "Breast cancer": 12.773341168622522, "Breast cancer metastatic": 138.3994817997619, "Burning sensation": 2.8588241058322024, "Cellulitis": 2.494823195421424, "Cholangitis": 15.685979048365702, "Colitis": 3.2960868771241767, "Cytogenetic analysis abnormal": 137.05939990758466, "Dehydration": 2.8097865473627905, "Disease progression": 5.21830205447912, "Drug-induced liver injury": 2.004265402097739, "Dyspnoea exertional": 3.8190710535249415, "Enterocolitis": 11.859604200114305, "Febrile neutropenia": 11.1327560184904, "Gene mutation": 91.3961623391678, "Hepatic lesion": 55.30702437836333, "Hypophagia": 23.78003164441682, "Hypoxia": 2.816162523260792, "Immune-mediated enterocolitis": 17.59032851999298, "Interstitial lung disease": 10.92154847537796, "Joint stiffness": 8.050645948755175, "Liver disorder": 2.642989716356119, "Malignant neoplasm progression": 23.199986162423457, "Metastases to bone": 67.35189139787303, "Metastases to central nervous system": 13.197444504172031, "Metastases to liver": 33.89317051002639, "Metastases to lung": 27.63412771485676, "Metastases to pelvis": 264.92328007524685, "Metastases to peritoneum": 49.41912303055205, "Metastases to skin": 81.71431836821557, "Metastasis": 30.71685088447018, "Mouth ulceration": 9.370436500008594, "Mucosal inflammation": 4.013792314933522, "Myelosuppression": 5.778864293248316, "Nail avulsion": 1241.19955539701, "Neoplasm progression": 12.139220611551323, "Neuropathy peripheral": 8.785004301437997, "Neutropenia": 3.591824914948494, "Neutrophil count decreased": 3.848992886754123, "PIK3CA-activated mutation": 384.2762242630757, "Palmar-plantar erythrodysaesthesia syndrome": 3.692960490420063, "Pancreatic carcinoma": 3.9089567940666585, "Pancreatic carcinoma metastatic": 22.55899605603173, "Peripheral sensory neuropathy": 14.671557522902848, "Pleural effusion": 8.436913854392818, "Pneumonitis": 10.89664039951243, "Pulmonary mass": 23.2670822950978, "Skin disorder": 2.1930768722299785, "Spinal compression fracture": 11.192615021638726, "Staphylococcal infection": 5.857026410008794, "Stomatitis": 5.317968489156255, "Thrombocytopenia": 2.4600118324117664, "Tumour marker increased": 50.55661377691028, "White blood cell count decreased": 2.5571074605085102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/110.json
index 3cbe9ee3306..3a278749ada 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/110.json
@@ -1 +1 @@
-{"Condition aggravated ": 7.384056038991352}
\ No newline at end of file
+{"Abnormal behaviour": 4.064001302398715, "Abnormal weight gain": 3.233028517882534, "Acarodermatitis": 40.25045883080527, "Adverse drug reaction": 2.172790258980814, "Affect lability": 2.742677277780885, "Affective disorder": 27.388828157449165, "Aggression": 4.1045713440188525, "Agitation": 4.19631282388288, "Akathisia": 85.09058944866679, "Alcohol abuse": 12.247975009462294, "Anosognosia": 42.15155843728424, "Anticholinergic syndrome": 12.20158153020344, "Antipsychotic drug level above therapeutic": 18.30649099055507, "Antipsychotic drug level below therapeutic": 447.8543929155082, "Antipsychotic drug level increased": 15.017038945774674, "Anxiety disorder": 2.503564679184128, "Appetite disorder": 2.582162046839529, "Arteriosclerosis coronary artery": 5.498023834693302, "Asphyxia": 2.1169998358524684, "Attention deficit hyperactivity disorder": 2.7455099445865887, "Autonomic nervous system imbalance": 6.512937653076763, "Basilar artery occlusion": 87.22480467605527, "Behaviour disorder": 3.27342448400922, "Blood albumin decreased": 8.765449133550183, "Blood creatine phosphokinase increased": 3.558922735105308, "Blood creatinine decreased": 3.4657063900104284, "Blood insulin increased": 20.417740324734883, "Blood magnesium increased": 37.46717710765861, "Blood osmolarity increased": 20.72281943258732, "Blood prolactin abnormal": 57.95968182027041, "Blood prolactin increased": 15.30190465051583, "Blood thyroid stimulating hormone increased": 7.60986668818652, "Blood triglycerides increased": 2.534480726308981, "Blood urea increased": 2.654226239644935, "Body dysmorphic disorder": 28.42120188953433, "Body mass index increased": 11.418051915576209, "Bradykinesia": 4.687434087044972, "Bruxism": 10.679561069778636, "Bundle branch block right": 2.67589587059719, "C-reactive protein increased": 2.3444009485669914, "Cardiac dysfunction": 14.908669678459162, "Cardio-respiratory arrest": 3.775844417400084, "Cardiomegaly": 3.3743917094776688, "Cardiomyopathy": 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count decreased": 5.297627607709581, "Epidural lipomatosis": 126.89755851371504, "Euphoric mood": 65.5007457780649, "Exercise lack of": 36.90440477866854, "Extrapyramidal disorder": 49.69918808221738, "Feeling guilty": 9.989508817217072, "Fibrosis": 4.041501462766648, "Foetal disorder": 66.21475681325335, "Food craving": 12.500409241475626, "Galactorrhoea": 4.745979295691932, "Gambling disorder": 9.530642884449946, "Gaze palsy": 3.354433281552398, "Globulins increased": 138.1780621387131, "Glomerular filtration rate decreased": 2.9899077985654694, "Gynaecomastia": 5.565816411905163, "Hallucination, auditory": 26.457331338797804, "Hallucination, tactile": 79.5854412150779, "Hallucination, visual": 4.87036678891114, "Hallucinations, mixed": 10.301920476254049, "Head titubation": 34.14094511770808, "Hepatic fibrosis": 4.628705886676309, "Herpes simplex": 5.092487444046704, "High density lipoprotein decreased": 23.52138364077873, "Homicidal ideation": 6.960114260619189, "Hospitalisation": 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arthritis": 8.316406116964382, "Left atrial dilatation": 70.75078398482489, "Left ventricular dysfunction": 16.87092705486774, "Leukaemia": 29.13410432258982, "Leukocytosis": 5.212062390458086, "Leukopenia": 9.872595210261888, "Logorrhoea": 3.998342825051942, "Low birth weight baby": 5.163547717350982, "Low density lipoprotein increased": 3.670074283232927, "Lymphocyte count abnormal": 146.98008836534234, "Lymphocyte count decreased": 17.931408777036363, "Lymphocyte count increased": 9.737795438363294, "Mania": 9.611641253537051, "Maternal exposure during pregnancy": 2.1916406787784988, "Mean cell haemoglobin concentration decreased": 11.68444987477716, "Mean cell haemoglobin decreased": 13.967259620590864, "Mean cell haemoglobin increased": 8.464716193731372, "Mean cell volume decreased": 8.817664404249829, "Mental disorder": 2.7761796528452325, "Mental impairment": 4.026460685842072, "Metabolic disorder": 9.386361982991838, "Metabolic syndrome": 8.846077433684453, "Mitral valve incompetence": 3.929280465642666, "Monocyte count increased": 5.405187301206565, "Mood altered": 4.222074858782516, "Mucosal inflammation": 4.5176221207316765, "Muscle rigidity": 8.692299447812257, "Mutism": 20.354329824888232, "Myocarditis": 2.110092669167389, "Myoclonic epilepsy": 4.042557231707174, "Myoclonus": 2.7711960061955074, "Negative symptoms in schizophrenia": 336.27209650344435, "Negative thoughts": 5.533513576032692, "Negativism": 22.98327458530949, "Nephrogenic diabetes insipidus": 6.073520351984072, "Neuroleptic malignant syndrome": 16.887384496208956, "Neutropenia": 2.401621232369953, "Neutropenia neonatal": 315.01984304075387, "Neutrophil count decreased": 2.1059773974994225, "Neutrophil count increased": 37.58813250641392, "Neutrophilia": 3.743890236197738, "Non-alcoholic steatohepatitis": 15.59762698784544, "Non-high-density lipoprotein cholesterol increased": 329.14308956745907, "Obesity": 24.235245202623183, "Obsessive-compulsive disorder": 117.35073665388713, "Obsessive-compulsive symptom": 36.53754697222513, "Oculogyric crisis": 20.96218258056981, "Oppositional defiant disorder": 56.73320212124985, "Orthostatic hypertension": 19.914827209529804, "Orthostatic hypotension": 5.215761112477222, "Overdose": 2.727399985808901, "Panic disorder": 5.837888536493575, "Paradoxical drug reaction": 5.961315765377827, "Paranoia": 8.103336412672641, "Parkinsonism": 19.471873678184963, "Persecutory delusion": 24.16153176144859, "Personality change": 5.00734670405018, "Poisoning deliberate": 2.2592281817235875, "Post-traumatic pain": 34.443209289595025, "Posture abnormal": 4.452125990387526, "Pregnancy": 3.739111846796104, "Premature baby": 4.330123005810009, "Premature delivery": 12.10059830412037, "Prescribed overdose": 11.667094273120467, "Priapism": 8.95496103338074, "Product administered to patient of inappropriate age": 3.6009262160802407, "Product prescribing error": 3.5906746110044043, "Product use in unapproved indication": 3.834646916956757, "Product use issue": 2.9538485277135487, "Progressive multiple sclerosis": 62.86811533630221, "Psychiatric decompensation": 7.0087054985813655, "Psychiatric symptom": 2.9268302724957804, "Psychomotor hyperactivity": 5.780051026120516, "Psychomotor retardation": 9.64151384720076, "Psychotic disorder": 16.5266115426672, "Psychotic symptom": 45.82450571885816, "Pulmonary valve incompetence": 49.94088352231433, "Quadriparesis": 4.792505042597516, "Rebound effect": 5.104471160542829, "Red blood cell count decreased": 2.692430227343563, "Red cell distribution width increased": 21.72571102155434, "Respiratory acidosis": 4.604598589189398, "Respiratory arrest": 2.4303484268856086, "Respiratory depression": 8.266064383478582, "Resting tremor": 14.274465229510971, "Restless legs syndrome": 2.8839581706793047, "Restlessness": 3.140797179027577, "Rhinalgia": 44.776707830639154, "SARS-CoV-2 test positive": 5.0544471936301445, "Salivary hypersecretion": 12.629509659212458, "Schizoaffective disorder": 398.4730397608223, "Schizophrenia": 55.57949769033774, "Sedation": 15.829448250433533, "Sedation complication": 29.498691412920326, "Self-destructive behaviour": 4.177068969358874, "Self-injurious ideation": 2.885631009687697, "Self-medication": 8.770424244158582, "Serotonin syndrome": 8.618418755584734, "Sexual dysfunction": 10.463862094157554, "Sinus bradycardia": 2.422321200371797, "Sinus rhythm": 101.97435063046274, "Sinus tachycardia": 6.62005948899831, "Social anxiety disorder": 48.8681090785081, "Social avoidant behaviour": 9.202454741665868, "Somatic symptom disorder": 9.345747886914287, "Spasmodic dysphonia": 83.13224177148385, "Staring": 3.8793413088113753, "Steatohepatitis": 32.99114859274415, "Streptococcal infection": 4.486400403880586, "Substance use": 12.07500728793456, "Suicidal behaviour": 4.063083944034012, "Suicidal ideation": 3.112290232557721, "Suicide attempt": 11.116101266896798, "Suspected suicide": 10.0974205906934, "Sydenham's chorea": 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3.841936902289118, "Victim of child abuse": 113.02323698344291, "Vitamin B12 increased": 52.62524406849989, "Weight abnormal": 15.91470130597586, "Weight increased": 8.566440508145584, "White blood cell count increased": 2.200471054833264}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1100.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1100.json
index 9e26dfeeb6e..6e1b5334f7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1100.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1100.json
@@ -1 +1 @@
-{}
\ No newline at end of file
+{"Asphyxia": 3.1347416653246403, "Blindness": 5.665544494556956, "Blood glucose abnormal": 31.597072799389988, "Blood glucose decreased": 27.680425353446108, "Blood glucose fluctuation": 36.943233230655885, "Blood glucose increased": 31.48533019181776, "Caesarean section": 6.202470264167431, "Cardiac disorder": 2.6994414625406207, "Cataract": 7.476190820516678, "Cerebrovascular accident": 2.801632446942508, "Dementia": 6.092282818276282, "Device defective": 35.492507007626386, "Device delivery system issue": 18.7685460851876, "Device issue": 29.77402528459545, "Device leakage": 6.918160748120319, "Device occlusion": 10.82765539844747, "Device operational issue": 243.5743004184508, "Diabetes mellitus inadequate control": 73.25068238530734, "Diabetic ketoacidosis": 3.78987716326205, "Diabetic metabolic decompensation": 43.04469094927012, "Disability": 14.68356855096157, "Drug dose omission by device": 11.456468695840517, "Drug ineffective": 2.663595166141397, "Expired product administered": 3.7689565369952063, "Extra dose administered": 8.135734389530755, "Eye disorder": 2.5231741222247206, "Eye haemorrhage": 3.167798709297984, "Feeling abnormal": 2.199690530577856, "Glaucoma": 3.3578785022059754, "Glycosylated haemoglobin abnormal": 26.25361228980562, "Glycosylated haemoglobin increased": 29.2511753821142, "Hospitalisation": 3.132614835169901, "Hyperglycaemia": 25.28186019143705, "Hypoacusis": 3.282747246954409, "Hypoglycaemia": 16.311526051220454, "Hypoglycaemic coma": 2.698932040269262, "Hypoglycaemic unconsciousness": 4.741306184073823, "Inappropriate schedule of product administration": 7.017598988595349, "Incorrect dose administered": 5.018029843012827, "Incorrect dose administered by device": 28.157920482205046, "Injection site bruising": 9.702491641405846, "Injection site haemorrhage": 6.315330031783683, "Injection site mass": 4.058109619468821, "Intentional dose omission": 8.955473371269257, "Intentional product misuse": 3.832139251058136, "Intentional product use issue": 4.008458175524142, "Ketoacidosis": 3.240557177342316, "Loss of consciousness": 2.022852323504134, "Multiple use of single-use product": 36.7594532910498, "Needle issue": 6.434243098805027, "Neoplasm malignant": 2.424678179938528, "Nervousness": 3.000444619679882, "Product dispensing error": 2.7433617618824675, "Product dose omission in error": 6.405887570616123, "Product dose omission issue": 4.9971316912930535, "Product prescribing issue": 4.653400593218763, "Product quality issue": 10.657454019343618, "Product storage error": 52.87165737838029, "Product use issue": 3.8809653362097616, "Renal disorder": 3.142712900598831, "Stress": 2.5029855386445985, "Surgery": 3.3646165505663075, "Therapeutic response decreased": 4.557087721233061, "Thirst": 2.8953953280919102, "Unevaluable event": 6.197248355539708, "Visual impairment": 5.016017648068181, "Weight increased": 2.615702395813786, "Wrong technique in device usage process": 23.08276218074281}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1101.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1101.json
index 1e22a7ecc0a..37f2c2a0329 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1101.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1101.json
@@ -1 +1 @@
-{"Accidental overdose ": 2.6296123090845573, "Blood glucose abnormal ": 24.78087972701366, "Blood glucose decreased ": 21.925609170856852, "Blood glucose fluctuation ": 25.67302017667002, "Blood glucose increased ": 24.89259312866018, "Device breakage ": 19.875154519408607, "Device delivery system issue ": 33.96164898780047, "Device failure ": 20.80422867717287, "Device information output issue ": 99.2683663129178, "Device issue ": 16.856776104887295, "Device malfunction ": 15.91965837454006, "Diabetes mellitus inadequate control ": 27.95744980032748, "Diabetic ketoacidosis ": 16.455383706552617, "Diabetic retinopathy ": 17.975350852567903, "Disability ": 4.77506479281863, "Extra dose administered ": 13.95824173359262, "Glycosylated haemoglobin increased ": 8.825457644016875, "Hyperglycaemia ": 23.67249654949432, "Hypoglycaemia ": 44.71434145469532, "Hypoglycaemia unawareness ": 55.28012463875248, "Hypoglycaemic coma ": 28.577169929718732, "Hypoglycaemic encephalopathy ": 55.52741387045964, "Hypoglycaemic seizure ": 32.33507975526325, "Hypoglycaemic unconsciousness ": 78.91608763242286, "Impaired gastric emptying ": 13.91172119293204, "Incorrect dose administered ": 2.783135611353261, "Incorrect dose administered by device ": 60.87053935262371, "Injection site pruritus ": 3.2954319615690504, "Intentional overdose ": 5.235566304593297, "Ketoacidosis ": 5.480055809648136, "Limb injury ": 5.233675930073246, "Liquid product physical issue ": 29.878842219642, "Liver function test increased ": 2.782408170438118, "Maternal exposure during pregnancy ": 2.10005472095654, "Nephropathy ": 4.671340145678388, "Neuropathy peripheral ": 2.9406692683828872, "Pancreatic carcinoma ": 3.7379279644261154, "Premature baby ": 2.0994361272620186, "Product dispensing error ": 5.750628610143592, "Product leakage ": 28.020593773302192, "Product physical issue ": 37.1247308729641, "Product quality issue ": 21.20750203961347, "Product storage error ": 9.764039170526528, "Retinopathy ": 23.98402611984035, "Road traffic accident ": 2.666570865626205, "Suicide attempt ": 3.847560914975192, "Therapeutic product effect decreased ": 2.215786743725417, "Treatment noncompliance ": 4.498709346364353, "Weight increased ": 3.1253451853396284, "Wrong technique in product usage process ": 2.402019488954961}
\ No newline at end of file
+{"Accident": 4.687288606191155, "Anal incontinence": 2.86666338473011, "Angle closure glaucoma": 5.705853653412107, "Anticholinergic syndrome": 14.658867231176783, "Aphonia": 2.386394544325944, "Back disorder": 4.491182956468194, "Benign prostatic hyperplasia": 24.31190126888239, "Bladder dilatation": 41.391904487724005, "Bladder disorder": 25.227542981438216, "Bladder obstruction": 96.28437012166049, "Bladder pain": 39.66649432765731, "Bladder spasm": 46.27468605207611, "Blindness": 2.255868560268788, "Blood urine present": 6.4138136772640895, "Body height decreased": 17.66579520163965, "Cataract": 2.5011124588853395, "Cerebral disorder": 3.632783778645541, "Cerebrovascular accident": 2.4616770372459458, "Cognitive disorder": 3.928432262636733, "Confusional state": 2.160341801823328, "Constipation": 6.035025213305628, "Cystitis": 11.190037512622222, "Dementia": 18.64045421702887, "Dementia Alzheimer's type": 6.946127994218147, "Drug ineffective": 2.0789352452728878, "Dry eye": 10.75103012716396, "Dry mouth": 21.3394156589005, "Dry throat": 19.85959229979885, "Dysgraphia": 6.4057347398106215, "Dysphagia": 2.696459266231248, "Dysphonia": 2.247012548641629, "Dysstasia": 2.283403476661986, "Dysuria": 27.516202212383007, "Eructation": 3.4894684076972378, "Expired product administered": 3.0213527704479746, "Extra dose administered": 2.127016158423624, "Eye disorder": 3.862410515655502, "Faecaloma": 6.322670950683489, "Fall": 2.765221589106272, "Feeling abnormal": 2.072815600326237, "Fluid retention": 2.902403617672097, "Gait disturbance": 2.5453082755123235, "Gingival pain": 3.49278620452905, "Glaucoma": 7.079840221839622, "Head injury": 2.3192771840047235, "Hydronephrosis": 6.592974148708766, "Hypertonic bladder": 20.09643440232842, "Hypoacusis": 4.831763995942214, "Hypotonic urinary bladder": 167.9625798856184, "Ileus": 3.5806682207386484, "Illness": 2.291088240965124, "Implant site erosion": 169.6004886034721, "Implant site infection": 59.44726748539614, "Inappropriate antidiuretic hormone secretion": 2.4605908820595768, "Incontinence": 6.274686445724933, "Intentional product misuse": 2.1827080823906493, "Intestinal obstruction": 2.8572165296643317, "Intraocular pressure increased": 4.718217787779083, "Joint injury": 2.7403460407402047, "Kidney infection": 3.9097138864339738, "Lip dry": 7.053491848512653, "Lip swelling": 2.364781242972004, "Memory impairment": 3.3007688490311677, "Mental impairment": 3.975150120917871, "Micturition disorder": 16.291095437403083, "Micturition urgency": 23.460789938807768, "Middle insomnia": 5.353819996751486, "Mouth swelling": 3.290525796172336, "Multiple sclerosis": 6.419184797446486, "Muscle tightness": 4.817108927544359, "Musculoskeletal disorder": 8.345203948297033, "Nasal dryness": 8.477493313926937, "Neoplasm malignant": 2.416904902567219, "Nocturia": 18.684595985090297, "Overweight": 6.977681065854134, "Parkinson's disease": 11.154932242831832, "Pelvic pain": 4.3015003600387685, "Performance status decreased": 6.270564642182218, "Pharyngeal swelling": 2.2650142803064, "Pollakiuria": 11.34076737873998, "Post micturition dribble": 133.10271977977422, "Product dispensing error": 5.17099796717938, "Product prescribing error": 6.357167940172565, "Prostatic disorder": 9.568910677146164, "Prostatomegaly": 10.84742633209079, "Pyelonephritis": 2.459373624519442, "Residual urine volume increased": 467.9031164856961, "Road traffic accident": 2.2744803416205794, "Sinus disorder": 2.8776509727295245, "Speech disorder": 2.191302984058232, "Spinal disorder": 6.368500708687698, "Subileus": 13.920481368522324, "Swollen tongue": 2.633845946699353, "Therapeutic product effect incomplete": 5.724249445277831, "Therapeutic response decreased": 4.108954361501141, "Thirst": 8.227023601584046, "Unevaluable event": 2.53481196005712, "Urge incontinence": 35.666869643098714, "Urinary hesitation": 29.163745407333025, "Urinary incontinence": 12.796172326019976, "Urinary retention": 300.15280838641866, "Urinary tract disorder": 13.922313747760397, "Urinary tract infection": 5.819138300245455, "Urinary tract obstruction": 24.78550128291997, "Urine abnormality": 7.234271439301564, "Urine flow decreased": 61.63556198322418, "Urine output decreased": 2.961186779368628, "Vision blurred": 4.571683440713003, "Weight bearing difficulty": 8.776479087454058, "Weight fluctuation": 7.170977782469854, "Wound dehiscence": 28.50521307785547, "Wound drainage": 169.6004886034721, "Wrist fracture": 2.138625514083853, "Wrong technique in product usage process": 2.1179398221122367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1102.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1102.json
index b92fa5dd892..8bd0058f4fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1102.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1102.json
@@ -1 +1 @@
-{"Coma ": 26.76009390116617, "Completed suicide ": 82.87532264830675, "Intentional overdose ": 36.2364660944628, "Suicide attempt ": 27.074442430164652, "Tachycardia ": 12.793091217161722, "Toxicity to various agents ": 24.975687897462016}
\ No newline at end of file
+{"Acne cystic": 2.4786181032861507, "Acute macular neuroretinopathy": 2.7950133221848867, "Adnexa uteri pain": 2.069224810239992, "Ageusia": 2.0444294047324627, "Allergy to arthropod bite": 2.3771964655128923, "Allergy to vaccine": 8.84626198292469, "Anosmia": 2.8076777477196586, "Anovulatory cycle": 3.01071021790194, "Arthritis reactive": 3.6002155017639565, "Asthenopia": 3.6379357678172055, "Autoimmune arthritis": 3.0855043022153428, "Autoimmune disorder": 2.0370631748293726, "Autoscopy": 2.8255565826074887, "Axillary mass": 6.892638116911817, "Axillary pain": 5.697151655923116, "Bell's palsy": 9.484947979037566, "Blue toe syndrome": 3.8178561489800327, "Body temperature abnormal": 2.828660411018392, "Body temperature fluctuation": 2.6706056867124373, "Bone swelling": 3.4534360275379266, "Brain fog": 6.562658577159108, "Breast mass": 2.480283458762962, "Breast pain": 2.880208961373623, "Breast swelling": 3.0689639395958626, "Burning feet syndrome": 2.2475862207576998, "Burning sensation": 2.0771455928455937, "COVID-19": 4.37874169778368, "COVID-19 pneumonia": 2.029077325726268, "Cardiac flutter": 11.244591688467043, "Cardiac infection": 5.243089281848847, "Carditis": 4.194988060949562, "Cerebellar stroke": 2.067766896232316, "Cerebral thrombosis": 2.5293017842555323, "Chest crushing": 5.373582075129323, "Chest discomfort": 2.0075874823665703, "Chest pain": 2.794136759600997, "Chillblains": 2.7959002409491296, "Chronic fatigue syndrome": 2.818251216715979, "Chronic spontaneous urticaria": 2.1441269114876107, "Cluster headache": 4.656933853030841, "Cold sweat": 2.5543404859734338, "Cold-stimulus headache": 3.4895024839204045, "Conversion disorder": 2.019462108444354, "Corneal graft rejection": 3.259428357113452, "Corneal reflex decreased": 2.367378678169929, "Costochondritis": 5.884881665427233, "Deafness": 2.364032310787088, "Deafness unilateral": 3.695659404999448, "Dermatomyositis": 2.0359506370563034, "Disease recurrence": 6.736205043999007, "Disseminated Bacillus Calmette-Guerin infection": 9.130387982057467, "Dizziness exertional": 3.262931345473014, "Dizziness postural": 4.191479627079974, "Drug ineffective": 2.143864903719664, "Dysmenorrhoea": 5.361330102462249, "Dysstasia": 2.0577220277264505, "Ear congestion": 2.7478362728536005, "Ear discomfort": 3.3371506972454763, "Ear disorder": 2.245239202413107, "Ear pain": 3.283027618994242, "Ear swelling": 2.431996243451363, "Endocrine ophthalmopathy": 2.5311974833088304, "Endometriosis": 2.464873320203884, "Enlarged uvula": 3.5281038802941698, "Exposure to SARS-CoV-2": 5.353682773740538, "Eye injury": 2.3565603792933043, "Eye pain": 2.555395837569119, "Eye swelling": 2.797736897130525, "Eyelid pain": 2.597665550985389, "Eyelids pruritus": 2.224330633051527, "Facial discomfort": 3.7105819366293176, "Facial pain": 3.602684153660225, "Facial paralysis": 3.2161340907459475, "Facial spasm": 3.522918539104447, "Feeling abnormal": 2.276467316312557, "Feeling cold": 2.219087392015064, "Feeling hot": 2.104882907557666, "Feeling of body temperature change": 3.948934846546209, "Gingival blister": 2.16759500337661, "Glomerulonephritis minimal lesion": 4.624798922546271, "Guillain-Barre syndrome": 2.412747139980594, "Hangover": 3.368834741093996, "Head discomfort": 2.4908562876262814, "Heart rate": 2.2240491234225117, "Heart rate abnormal": 4.573050528565459, "Heart rate increased": 2.595452403689767, "Heart rate irregular": 2.4796071332683014, "Heavy menstrual bleeding": 4.185421024327055, "Hemiplegic migraine": 6.398572412270908, "Hyperacusis": 2.655667849857364, "Hypersomnia": 2.329664255593047, "Hypoaesthesia": 2.537594586481021, "Hypoaesthesia eye": 3.365006154547727, "Hypoaesthesia oral": 3.2935742452394146, "Hypokinesia": 2.469675896943856, "Hypomenorrhoea": 3.2951862130804512, "Hypopnoea": 2.7965479484497857, "IVth nerve paralysis": 2.6299751504756195, "IgA nephropathy": 2.4068217563636622, "Illness": 3.222560210316256, "Immunisation": 4.138153125225917, "Inappropriate 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"Menstruation irregular": 3.5346631839098954, "Mental fatigue": 5.22347467043066, "Metamorphopsia": 2.2822765888010004, "Migraine": 3.114680014633353, "Migraine with aura": 3.997243033140745, "Miliaria": 3.788329273915224, "Monoplegia": 2.4893079930764737, "Morning sickness": 2.3419274388004854, "Motion sickness": 4.744782369899864, "Motor neurone disease": 2.068285614756848, "Movement disorder": 2.053709617537133, "Multisystem inflammatory syndrome": 3.776242766753983, "Multisystem inflammatory syndrome in children": 6.540735860983297, "Muscle fatigue": 4.273675513577593, "Muscle swelling": 2.7751797277748764, "Muscle tightness": 2.2376296785631147, "Muscle twitching": 2.213556776085967, "Musculoskeletal chest pain": 2.2784502695293862, "Myelitis transverse": 4.402168489167463, "Myocardial injury": 2.322286854540389, "Myocardial oedema": 2.7008779523353525, "Myocarditis": 4.344279192789194, "Myopericarditis": 5.760693736721654, "Nasal congestion": 2.1794576690897145, "Near death 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"Paraesthesia oral": 2.6032653921248725, "Paralysis": 2.5985894705663344, "Paranasal sinus discomfort": 3.2627994880564866, "Pelvic haemorrhage": 6.099799054429683, "Periarthritis": 4.129747993876764, "Pericarditis": 2.795416731156919, "Periorbital swelling": 2.258499563306972, "Peripheral swelling": 2.239675137866066, "Pernio-like erythema": 9.693276230722391, "Persistent postural-perceptual dizziness": 4.606434254499339, "Pharyngeal hypoaesthesia": 3.4974355688067407, "Pharyngeal mass": 3.321845601169696, "Pharyngeal paraesthesia": 2.3445977708030337, "Pharyngeal swelling": 2.496075794720312, "Photophobia": 2.35661026962139, "Photopsia": 2.367632012385012, "Piloerection": 2.014464291296056, "Pityriasis": 3.2525906373978835, "Pityriasis rosea": 2.81306213436927, "Pleuritic pain": 2.9468304822548657, "Polycystic ovarian syndrome": 2.201333998105263, "Polymerase chain reaction positive": 6.7230923497759845, "Polymyalgia rheumatica": 2.61180083887474, "Postmenopausal haemorrhage": 3.342865482825633, "Postural orthostatic tachycardia syndrome": 3.883613187281696, "Premenstrual dysphoric disorder": 6.27280509534854, "Premenstrual pain": 3.8623488590802406, "Premenstrual syndrome": 2.503938206148295, "Primary stabbing headache": 2.261330537078811, "Product administered at inappropriate site": 2.2809560498663406, "Product temperature excursion issue": 2.0359789186141377, "Pulmonary pain": 2.737885444071809, "Pulmonary thrombosis": 2.9183628753895667, "Radiculitis brachial": 4.140196979606087, "Respiratory distress": 3.5820202464976783, "Retinal migraine": 6.998478303758776, "Retinal white dots syndrome": 13.564566377877211, "Rhinorrhoea": 3.1708358649199666, "SARS-CoV-2 test positive": 2.155046444553194, "Scrotal pain": 2.031257449974808, "Sensation of blood flow": 2.2627561038441497, "Sensitive skin": 18.042865623923763, "Sensory loss": 2.141296032699535, "Shoulder injury related to vaccine administration": 4.44935992418146, "Sinus congestion": 2.1981327011364646, "Sinus headache": 5.524699695777712, "Sinus pain": 3.982457424756957, "Sitting disability": 2.596678462965661, "Skin warm": 2.144832538028975, "Small fibre neuropathy": 3.890663665054416, "Sneezing": 2.4120233289624067, "Still's disease": 2.2060771190084827, "Suspected COVID-19": 23.59762558146328, "Sweating fever": 4.352045209238904, "Swelling": 2.2506712225314667, "Swelling face": 2.0009851322772434, "Swollen tongue": 2.04924369262574, "Syncope": 2.347251733727326, "Temperature difference of extremities": 3.689359675250836, "Tension headache": 3.8667162301681466, "Throat tightness": 2.933677129185047, "Thrombosis": 2.639101132636042, "Thunderclap headache": 3.101041709969715, "Thyroid pain": 2.478072732232738, "Thyroiditis subacute": 5.14619880374188, "Tinnitus": 2.8561861639942334, "Tonsillar hypertrophy": 2.7545869053763066, "Tunnel vision": 3.355527524480604, "Upper respiratory tract congestion": 3.513778388170308, "Urticaria chronic": 2.203612449146592, "Vaccination error": 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"Vestibular neuronitis": 2.0577676357140224, "Viral pharyngitis": 2.639525593829867, "Viral rash": 2.634800219569762, "Visual snow syndrome": 3.536369558146257, "Vomiting projectile": 2.367964390180853, "Vulval haemorrhage": 10.077232026151933, "Vulval ulceration": 3.7062297903944574}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1103.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1103.json
index e4cc6e2dddf..287e7e680a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1103.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1103.json
@@ -1 +1 @@
-{"Nervous system disorder ": 75.2965792521512}
\ No newline at end of file
+{"Acute kidney injury": 2.6540066578012853, "Alanine aminotransferase increased": 7.781080583349353, "Anaemia": 7.232512751105886, "Asthenia": 2.1407794670997173, "Disease progression": 4.981324741267289, "Febrile neutropenia": 10.616668020940304, "Hepatotoxicity": 19.16477250008546, "Hypertransaminasaemia": 61.68296180850008, "Leukopenia": 6.013309037707439, "Neutropenia": 19.82487729713077, "Off label use": 2.111850938532144, "Pancytopenia": 13.470615035928716, "Product use in unapproved indication": 3.36947644376982, "Rhabdomyolysis": 36.30981724335528, "Thrombocytopenia": 9.636911859870814, "Transaminases increased": 26.37806459325664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1104.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1104.json
index 556250133bb..12829de2c86 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1104.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1104.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.442187573669816, "Alanine aminotransferase increased ": 4.456980771431938, "Aspartate aminotransferase increased ": 3.995900329829647, "Differentiation syndrome ": 6457.682812330478, "Disseminated intravascular coagulation ": 12.92259288965895, "Electrocardiogram QT prolonged ": 87.4483537985836, "Febrile neutropenia ": 3.919462467594223, "Fluid retention ": 7.3652338003123585, "Hepatotoxicity ": 7.840642177793671, "Leukocytosis ": 16.82479904356629, "Neuropathy peripheral ": 7.451838352090976, "Neutropenia ": 4.0267261435181005, "Pancytopenia ": 4.657562294120532, "Pericardial effusion ": 9.680716121109253, "Pleural effusion ": 5.044322757776238, "Renal failure ": 2.459959758845987, "Ventricular extrasystoles ": 15.59342619253204, "Ventricular tachycardia ": 19.27148991246068, "Weight increased ": 3.089821969972661, "White blood cell count increased ": 9.473695475307954}
\ No newline at end of file
+{"Abortion induced": 6.086982017000009, "Acute respiratory distress syndrome": 2.070060503098204, "Acute respiratory failure": 6.624762921550798, "Alanine aminotransferase increased": 16.617943678441424, "Ammonia increased": 2.150567695161058, "Angioplasty": 8.806714440816204, "Anuria": 2.339000068891427, "Aortic stenosis": 6.174466580238899, "Ascites": 5.747668120628645, "Aspartate aminotransferase increased": 18.86373775276574, "Atrial flutter": 5.94304999987833, "Atrial septal defect repair": 144.42100034513936, "Autoimmune hepatitis": 3.228217651011847, "Bilirubin conjugated increased": 12.174626518170689, "Biopsy liver": 70.25801614930803, "Blood alkaline phosphatase increased": 22.12681368373806, "Blood bilirubin increased": 13.98380988349298, "Blood culture positive": 19.469518111938108, "Blood iron decreased": 2.378110733013505, "Blood potassium increased": 2.131973845850877, "Brain natriuretic peptide increased": 7.935174741042364, "Bronchitis": 2.36865969805664, "Carbon dioxide increased": 14.45324761587982, "Cardiac ablation": 14.403070509007652, "Cardiac arrest": 3.413382068506249, "Cardiac failure": 7.1725253445694825, "Cardiac failure acute": 6.1118079827408085, "Cardiac failure chronic": 4.221873232979084, "Cardiac failure congestive": 4.857787905738827, "Cardiac operation": 7.013534234440036, "Cardiac output decreased": 15.925781071101683, "Cardiac pacemaker insertion": 5.623846725932027, "Cardiac tamponade": 2.36056650742856, "Cardio-respiratory arrest": 2.4925442470817534, "Cardiopulmonary failure": 11.494998527235657, "Cardioversion": 5.413709178254137, "Catheter management": 79.899170970412, "Catheter placement": 28.57035584100068, "Catheter site discharge": 45.369781943060254, "Catheter site erythema": 45.78843151475421, "Catheter site haemorrhage": 14.83711954210299, "Catheter site infection": 38.86993871788317, "Catheter site pain": 28.16796955420939, "Catheter site pruritus": 18.204207325980374, "Catheter site swelling": 54.724099387738335, "Catheterisation cardiac": 19.746812608045573, "Central venous catheterisation": 7.387664812756595, "Chemotherapy": 8.63911813377018, "Cholecystectomy": 3.436167055841836, "Cholelithiasis": 2.0824844979410857, "Chronic obstructive pulmonary disease": 3.4988913242046955, "Chronic respiratory failure": 28.86776117167693, "Coagulation test abnormal": 7.406670897859708, "Complication associated with device": 15.85797292867412, "Concomitant disease aggravated": 11.830409118923937, "Concomitant disease progression": 7.660170385690843, "Condition aggravated": 4.040791798761954, "Congestive hepatopathy": 33.590721466936046, "Cor pulmonale": 75.32183481054007, "Cyanosis": 3.1980960721329104, "Death": 10.7464331906387, "Device alarm issue": 36.71919103493391, "Device breakage": 8.127515255569795, "Device dislocation": 7.139094717105061, "Device infusion issue": 14.312000949565482, "Device leakage": 12.499527746502226, "Device malfunction": 2.356471818319452, "Device occlusion": 11.960816242960972, "Device physical property issue": 9.672664379727996, "Device related infection": 10.561521861526485, "Device related sepsis": 13.396763461393135, "Dialysis": 7.093199902209117, "Disease complication": 24.96451421504545, "Disease progression": 6.610990059364696, "Dyspnoea": 2.893931519502753, "Dyspnoea exertional": 4.141406100953541, "Echocardiogram abnormal": 8.83963864030103, "Endarterectomy": 70.75848955340513, "Endocarditis": 2.3131091085449773, "Endotracheal intubation": 10.505880620412116, "Erysipelas": 2.0635038695183754, "Exercise tolerance decreased": 3.0743131068499108, "Failure to thrive": 3.595594437885426, "Fluid retention": 13.74204449800592, "Flushing": 2.161731312289462, "Gamma-glutamyltransferase increased": 8.540162960316653, "Gangrene": 3.409082278858314, "Gastroenteritis viral": 4.5318037632284405, "Gastrointestinal infection": 2.727520721167108, "Gastrointestinal motility disorder": 2.457210643549166, "Gastrointestinal tube insertion": 7.879626722451301, "General physical condition abnormal": 2.351162456505008, "Generalised oedema": 3.744146053088675, "Haematocrit decreased": 4.185402766710015, "Haemodynamic instability": 2.7061258934387142, "Haemoglobin decreased": 2.283445841864052, "Haemoptysis": 5.124650840363503, "Heart and lung transplant": 153.6498255998542, "Heart disease congenital": 2.1924865879802984, "Heart transplant": 44.40121679275831, "Hepatic cirrhosis": 3.263835706207077, "Hepatic cytolysis": 2.748228101769231, "Hepatic enzyme abnormal": 3.5663816642106645, "Hepatic enzyme increased": 2.367329622969917, "Hepatic failure": 2.4393427003107444, "Hepatomegaly": 3.3072012109477136, "Hip fracture": 2.583591211890956, "Hip surgery": 4.4099615264416165, "Hospitalisation": 3.345196572229051, "Hypervolaemia": 27.857632952953256, "Hypoxia": 10.650307872178091, "Infusion site erythema": 6.628843076772189, "Infusion site pain": 5.363027835015031, "International normalised ratio decreased": 4.734810183627554, "International normalised ratio increased": 2.111860339399548, "Intestinal ischaemia": 2.097674721476978, "Jaundice": 2.7808980535423427, "Left ventricular failure": 10.338111683798267, "Liver function test abnormal": 26.956228721887456, "Liver function test increased": 19.71060452045376, "Lung disorder": 2.384226814777129, "Lung infiltration": 2.5948201457208384, "Lung transplant": 101.10920016670671, "Mechanical ventilation": 16.09085387542, "Medical device change": 47.81268563204908, "Mineral supplementation": 43.14966987734736, "Multiple organ dysfunction syndrome": 3.7653623141773607, "N-terminal prohormone brain natriuretic peptide increased": 5.34967562309036, "Normal newborn": 3.4407828708352364, "Ocular icterus": 3.8830844366291073, "Oedema": 4.875915566124861, "Oedema peripheral": 4.762511399249857, "Orthopnoea": 8.420093556048611, "Oxygen consumption increased": 29.742254816213222, "Oxygen saturation abnormal": 7.189704036274527, "Oxygen saturation decreased": 6.225031051549515, "Oxygen therapy": 5.5005768303592655, "Pain in jaw": 4.122891400100203, "Paracentesis": 31.727211363231174, "Pericardial effusion": 4.794408175707647, "Platelet transfusion": 11.800070091411234, "Pleural effusion": 3.222154361947435, "Pneumonia": 3.926906343292319, "Pneumonia aspiration": 2.1604316075228915, "Pneumonia viral": 3.654001643077791, "Pneumothorax": 3.285757160738092, "Post procedural complication": 4.00504605451263, "Pregnancy": 12.145529984146064, "Prothrombin time prolonged": 2.5481573219932674, "Pulmonary arterial hypertension": 140.41012890439302, "Pulmonary arterial pressure increased": 34.96529188329854, "Pulmonary congestion": 3.4119826193508467, "Pulmonary fibrosis": 5.972027503145929, "Pulmonary haemorrhage": 5.261708859275798, "Pulmonary hypertension": 49.42326982649671, "Pulmonary hypertensive crisis": 157.9687662366876, "Pulmonary oedema": 5.328578210636702, "Pulmonary veno-occlusive disease": 23.360554708260626, "Pulseless electrical activity": 3.031727869409328, "Radiotherapy": 5.300263592362989, "Raynaud's phenomenon": 2.0397808543979017, "Red blood cell transfusion": 16.84039354442232, "Respiratory distress": 2.4865160126474946, "Respiratory failure": 10.224176765992247, "Respiratory syncytial virus infection": 2.4661660381695563, "Respiratory tract infection": 4.215746945787666, "Respiratory tract infection viral": 8.63540280505277, "Resuscitation": 9.112999858904097, "Rhinovirus infection": 11.829268524495577, "Right ventricular dysfunction": 19.92864815176336, "Right ventricular failure": 136.42799760721908, "Right-to-left cardiac shunt": 242.0200617494706, "Sarcoidosis": 2.1001413990118114, "Scleroderma": 38.12374010520422, "Seasonal allergy": 2.364734917583493, "Sepsis": 3.7257839710867375, "Septic shock": 2.370700903992396, "Skin ulcer": 3.500765816671256, "Staphylococcal infection": 2.826765265686747, "Staphylococcal sepsis": 2.4191864465016697, "Sudden cardiac death": 5.055599712276701, "Sudden death": 6.911537933427729, "Supraventricular tachycardia": 2.076142069136613, "Surgery": 2.725809193865039, "Systemic scleroderma": 35.71621698934188, "Terminal state": 15.756491734455532, "Therapy change": 3.9962170262754384, "Therapy non-responder": 2.285966424798865, "Tracheostomy": 17.597883895440866, "Transaminases increased": 2.8908588193518145, "Transfusion": 17.948926901163937, "Transplant": 15.042368387265812, "Transplant evaluation": 52.327285995031495, "Tricuspid valve incompetence": 3.259277291880033, "Unevaluable event": 2.724870025667716, "Upper respiratory tract infection": 2.6020171756417327, "Urine output decreased": 2.5096190737698203, "Vascular device infection": 28.89979877487792, "Viral infection": 3.599241436131178, "Walking distance test abnormal": 68.62983098871018}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1105.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1105.json
index f8e14e1c7c2..e07d4c19b2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1105.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1105.json
@@ -1 +1 @@
-{"Abnormal dreams ": 5.403626924150437, "Abortion spontaneous ": 2.1855466614040524, "Acute myocardial infarction ": 4.364114634545663, "Alanine aminotransferase increased ": 2.221817715406452, "Anxiety ": 2.5126702817908866, "Blood HIV RNA increased ": 94.5397674005564, "Blood creatinine increased ": 2.5162463048154478, "Chromaturia ": 2.6363422670054346, "Craniofacial fracture ": 16.00323880016695, "Cytomegalovirus infection ": 4.6028622834965125, "Depressed mood ": 4.915513682832467, "Depression ": 6.555983005847929, "Dermatitis allergic ": 3.777233281008909, "Diabetes mellitus ": 2.7495817701500176, "Drug-induced liver injury ": 5.9129766032483095, "Dyslipidaemia ": 9.697881093398912, "Exposure during pregnancy ": 2.17369320775612, "Flatulence ": 3.036245466205297, "Hepatitis ": 3.0237708836892208, "Hepatotoxicity ": 2.230755259211301, "Hospitalisation ": 3.81080986709355, "Hypertransaminasaemia ": 7.174762543246094, "Ill-defined disorder ": 2.4291469746753998, "Immune reconstitution inflammatory syndrome ": 21.4799484891294, "Insomnia ": 7.11788095279899, "Irritability ": 2.5452460949243254, "Jaundice ": 2.853275251708144, "Lipodystrophy acquired ": 12.824058483691358, "Liver function test increased ": 2.785495652725661, "Mental disorder ": 5.24950614546218, "Mood altered ": 3.3596108684714348, "Myocardial infarction ": 4.083600852210179, "Nervous system disorder ": 2.588420505184052, "Nightmare ": 10.760783163387798, "Pancreatitis ": 3.15892929738473, "Pancreatitis acute ": 2.332336366873145, "Panic attack ": 2.3615591326696896, "Psychotic disorder ": 3.3703636962415144, "Rhabdomyolysis ": 2.276912589685794, "Sleep disorder ": 6.430904232321366, "Suicidal ideation ": 7.231263881099052, "Suicide attempt ": 2.3458293195650377, "Transaminases increased ": 4.687114424525578, "Treatment noncompliance ": 5.5202989529101085, "Viral load increased ": 21.478645110576345, "Virologic failure ": 16.189584049400146, "Weight increased ": 6.25028232735625}
\ No newline at end of file
+{"Acute pulmonary oedema": 303.8077193865649, "Anaemia neonatal": 1509.8887549805152, "Atrial septal defect": 85.01316955297854, "Bradycardia foetal": 236.24926298570804, "Bradycardia neonatal": 536.6381484931023, "Cardiac failure": 4.617333842950248, "Chest discomfort": 2.4038881920687896, "Dyspnoea": 2.902511852761116, "Exposure during pregnancy": 7.37755324372561, "Foetal death": 90.95769082566837, "Foetal exposure during pregnancy": 20.554724924786896, "Foetal growth restriction": 83.26589431194269, "Hypotension": 3.930214107855156, "Hypoxia": 15.243559350458913, "Inguinal hernia": 71.60826009645038, "Jaundice": 8.924990547457472, "Low birth weight baby": 155.90377936877294, "Maternal exposure during pregnancy": 6.326833517989214, "Overdose": 3.1146338112295417, "Pericardial effusion": 11.84002971292918, "Pleural effusion": 10.503456730503782, "Premature baby": 118.04908072199056, "Premature labour": 55.9556496487921, "Product use in unapproved indication": 2.135912538280603, "Pulmonary hypertension": 24.30728274357121, "Pulmonary oedema": 44.54136136343621, "Respiratory distress": 9.164597783782272, "Tachycardia": 2.490858083706681}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1106.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1106.json
index 0ab8f59619c..5012199c181 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1106.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1106.json
@@ -1 +1 @@
-{"Anaemia ": 8.313266069890814}
\ No newline at end of file
+{"Chest pain": 5.392860257938281, "Hypoglycaemia": 32.59188134541195}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1107.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1107.json
index 39d43bd0419..aae58033e2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1107.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1107.json
@@ -1 +1 @@
-{"Alopecia ": 13.07590007382991, "Anaemia ": 4.488328381019586, "Asthenia ": 2.682341125616676, "Breast cancer metastatic ": 4.112835023218993, "Cholinergic syndrome ": 60.423254645511584, "Colitis ": 7.717976199434435, "Constipation ": 2.9900980141746687, "Cytopenia ": 3.517697347102612, "Death ": 5.879185040003085, "Diarrhoea ": 7.70959129632048, "Disease progression ": 61.36476883506372, "Dry skin ": 2.035998854606293, "Emotional disorder ": 8.24960300324811, "Enteritis ": 8.783494134932793, "Extravasation ": 14.92973406017034, "Febrile bone marrow aplasia ": 51.048881791699, "Febrile neutropenia ": 21.01203460348041, "General physical health deterioration ": 3.293896312853976, "Haematotoxicity ": 8.106610741968414, "Leukopenia ": 2.173023630650995, "Metastases to bone ": 4.608094214969409, "Metastases to central nervous system ": 31.637125528548697, "Metastases to liver ": 11.124902332275592, "Metastases to lymph nodes ": 6.426408142046866, "Metastases to meninges ": 37.27705422132789, "Metastasis ": 15.85493451381507, "Mucosal inflammation ": 16.592205532591443, "Myelosuppression ": 2.1499986772095654, "Neuropathy peripheral ": 2.093165513027973, "Neutropenia ": 39.57906270834863, "Neutropenic colitis ": 264.3894184690821, "Neutropenic sepsis ": 34.953182777898256, "Neutrophil count abnormal ": 24.273228276241984, "Neutrophil count decreased ": 3.81623650104666, "Pancytopenia ": 4.168216564960286, "Pneumonitis ": 13.655155478146348, "Sepsis ": 2.5141180713781943, "Septic shock ": 5.297168415788171, "Stomatitis ": 2.156881394561052, "Therapy partial responder ": 9.699055877011729, "Thrombocytopenia ": 3.635663898143392, "Triple negative breast cancer ": 210.4750744130611}
\ No newline at end of file
+{"Alopecia": 2.6241823660695704, "Dermatitis": 18.482951534780625, "Dermatitis acneiform": 178.3444788149086, "Disease progression": 5.1633589549275785, "Dry skin": 11.59659415397186, "Ejection fraction decreased": 25.74398628167961, "Folliculitis": 13.794110190105965, "Malignant neoplasm progression": 25.4187534355958, "Metastatic malignant melanoma": 432.5070243040728, "Paronychia": 142.97919276519008, "Product use in unapproved indication": 30.552040506122225, "Product use issue": 12.723801347784429, "Rash": 5.143558256953128, "Skin toxicity": 60.95514494200553, "Therapeutic response decreased": 8.513841285544412}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1108.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1108.json
index 43a2ab68446..80bfd368083 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1108.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1108.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.9599520689641263, "Abdominal distension ": 6.419063795242743, "Abdominal pain ": 3.620120907609257, "Abdominal pain upper ": 3.685588342464788, "Accidental overdose ": 2.658208553952218, "Accidental underdose ": 43.03843712659554, "Amylase increased ": 11.333830904616011, "Appetite disorder ": 2.1474708143991514, "Back disorder ": 2.1226926059458373, "Biliary colic ": 4.9969585461101165, "Blindness ": 2.665281332803318, "Blood glucose abnormal ": 10.467575420659744, "Blood glucose decreased ": 7.216397246987838, "Blood glucose fluctuation ": 2.718203392811243, "Blood glucose increased ": 10.073416218937318, "Blood triglycerides increased ": 5.552568769330999, "Bowel movement irregularity ": 3.267803353671958, "Brain neoplasm ": 2.265434111126974, "Breath odour ": 13.46262591544766, "Cerebrovascular accident ": 2.0985474120593346, "Cholecystitis ": 3.498049201045728, "Cholecystitis acute ": 3.1154684804962995, "Cholelithiasis ": 6.044942800254252, "Constipation ": 5.051091644598857, "Decreased appetite ": 4.66038886323866, "Dehydration ": 4.730365555745502, "Dementia ": 3.1000158853589075, "Dementia Alzheimer's type ": 3.838791649060912, "Diabetes mellitus inadequate control ": 6.013370393474809, "Diabetic complication ": 6.540771285488041, "Diabetic ketoacidosis ": 4.007679780105471, "Diabetic metabolic decompensation ": 5.187875080257822, "Diabetic neuropathy ": 4.413746809934038, "Diabetic retinopathy ": 7.79395430943083, "Diarrhoea ": 4.05986356883934, "Dyspepsia ": 5.444297239718352, "Eating disorder ": 2.22811241881299, "Eructation ": 64.50965298380565, "Extra dose administered ": 7.982154545373312, "Faeces hard ": 6.124392695066311, "Feeding disorder ": 10.424494113627816, "Flatulence ": 12.784514356380676, "Fluid intake reduced ": 4.781537736322375, "Food craving ": 8.09562298083101, "Gallbladder disorder ": 2.369736299881586, "Gastroenteritis viral ": 3.133622734061845, "Gastrointestinal disorder ": 4.785879419259922, "Gastrointestinal pain ": 2.829708585882691, "Gastrointestinal sounds abnormal ": 4.279817904951046, "Gastrooesophageal reflux disease ": 4.055070411224713, "Glomerular filtration rate decreased ": 4.345697265948747, "Glycosylated haemoglobin abnormal ": 14.252844878612102, "Glycosylated haemoglobin decreased ": 20.174378131012823, "Glycosylated haemoglobin increased ": 28.468341355961996, "Hiccups ": 6.6596385647474845, "Hunger ": 7.111055611999341, "Hyperlipasaemia ": 15.749250667716074, "Hypoglycaemia ": 2.7280772953959924, "Hypophagia ": 3.879379726599245, "Ileus ": 3.914229888618311, "Illness ": 3.754518789071537, "Impaired gastric emptying ": 22.36237884837358, "Inappropriate schedule of product administration ": 2.8026005234367504, "Incorrect dose administered ": 5.929511581967992, "Increased appetite ": 2.629854708006699, "Injection site bruising ": 12.956717524805022, "Injection site discomfort ": 5.248700777235031, "Injection site erythema ": 5.224260525478492, "Injection site haematoma ": 3.0528603582424934, "Injection site haemorrhage ": 16.92174243822442, "Injection site hypersensitivity ": 32.86994266286161, "Injection site induration ": 4.073613948589225, "Injection site injury ": 23.00373230491704, "Injection site irritation ": 13.961167707962874, "Injection site mass ": 16.36851395854585, "Injection site nodule ": 6.3388732274982456, "Injection site oedema ": 5.716416796659002, "Injection site pain ": 2.85446627575715, "Injection site plaque ": 30.059265813213, "Injection site pruritus ": 14.331781003929477, "Injection site rash ": 16.084646214496072, "Injection site reaction ": 3.0564400439672155, "Injection site urticaria ": 10.22369095720672, "Injection site vesicles ": 9.488777453942202, "Injury associated with device ": 8.359553808840856, "Intestinal obstruction ": 3.9566961672398295, "Ketoacidosis ": 3.762546353834728, "Lipase increased ": 27.81706180731476, "Medullary thyroid cancer ": 50.0158035998072, "Nausea ": 3.913777695990481, "Neoplasm malignant ": 3.5067715983238488, "Obstructive pancreatitis ": 16.89917769749009, "Pancreatic carcinoma ": 8.24885553272093, "Pancreatic carcinoma metastatic ": 7.679010726588554, "Pancreatic cyst ": 8.842036352729702, "Pancreatic disorder ": 13.075804190613146, "Pancreatic enzymes increased ": 5.944964742295338, "Pancreatic failure ": 13.605000342563953, "Pancreatic mass ": 13.502031179557513, "Pancreatitis ": 29.629314673776637, "Pancreatitis acute ": 12.953750442096418, "Pancreatitis chronic ": 5.617763541971441, "Pancreatitis necrotising ": 6.181048234022347, "Papillary thyroid cancer ": 6.215948186476563, "Product administered at inappropriate site ": 8.868154149359322, "Product dose omission issue ": 3.738456424015123, "Product storage error ": 3.657975720266613, "Regurgitation ": 5.142525928562297, "Renal disorder ": 2.34001483427858, "Retching ": 2.473882452579214, "Retinal detachment ": 2.1693043300112214, "Retinopathy ": 3.702058477784784, "Sleep disorder due to general medical condition, insomnia type ": 2.4503251544825257, "Small intestinal obstruction ": 4.960041638552545, "Thyroid cancer ": 11.520853832466871, "Thyroid mass ": 5.935347573442068, "Thyroid neoplasm ": 20.47303134348697, "Vomiting ": 5.505953775446867, "Vomiting projectile ": 11.763332078493436, "Weight decreased ": 6.563915876721717, "Weight increased ": 2.216653586397856}
\ No newline at end of file
+{"Anaemia": 2.9445581244438443, "Cardiac dysfunction": 388.6841683303037, "Cardiac failure": 7.6031991914788755, "Cardiomyopathy": 49.084121584695424, "Cardiotoxicity": 131.50693862250031, "Constipation": 2.3474564387636314, "Ejection fraction decreased": 48.92501618829007, "Enterocolitis": 65.77153017306227, "Febrile neutropenia": 26.77580130996868, "Interstitial lung disease": 3.606164845095734, "Malignant neoplasm progression": 2.757867358889308, "Myelosuppression": 23.164410871560133, "Neutropenia": 9.678533719253172, "Neutrophil count decreased": 7.749758097102998, "Septic shock": 13.413268875353484, "White blood cell count decreased": 4.2711855442322015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1109.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1109.json
index 4dd13f39ae9..3f861cde9e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1109.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1109.json
@@ -1 +1 @@
-{"Loss of consciousness ": 26.50042158332387, "Syncope ": 22.356515565132643}
\ No newline at end of file
+{"Cardiac arrest": 31.970430033842455, "Completed suicide": 72.86622490574653, "Respiratory arrest": 91.75444738262584}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/111.json
index 8382ab04439..b0be009e583 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/111.json
@@ -1 +1 @@
-{"Anaemia ": 2.4003178637361526, "Chronic lymphocytic leukaemia ": 162.22256830834638, "Colectomy ": 120.38516549874858, "Colitis ": 12.539528052800083, "Death ": 2.532092513273746, "Disease progression ": 4.333681094365547, "Febrile neutropenia ": 4.572052119832367, "Flushing ": 4.12308805517138, "Gastrooesophageal reflux disease ": 5.681558831972588, "Hepatic steatosis ": 17.234922817130382, "Infection ": 2.7860159443706847, "Infusion related reaction ": 14.8457164984654, "Intestinal obstruction ": 19.9927447730106, "Neutropenia ": 6.518697438948528, "Pneumonia ": 4.458591296339398, "Respiratory tract infection ": 14.017825957177514, "Sepsis ": 10.319379780683096, "Sleep disorder ": 3.9228860020879495, "Urticaria ": 2.239608770618571}
\ No newline at end of file
+{"Abdominal wall haematoma": 70.51519536618059, "Acute generalised exanthematous pustulosis": 13.558215731959434, "Acute kidney injury": 2.01767067173518, "Anaemia": 7.857211504725206, "Blood alkaline phosphatase increased": 3.456069793688746, "Blood loss anaemia": 44.05024982817037, "Bronchospasm": 3.66512353857739, "Cardiac arrest": 2.228897879388682, "Cerebral haemorrhage": 11.069180822578817, "Cholestasis": 5.817716679103597, "Chromaturia": 11.441608480541724, "Coagulopathy": 7.904383536646639, "Coma": 2.305248203011274, "Deep vein thrombosis": 2.794004113644586, "Dermatitis allergic": 5.038670178741249, "Drug reaction with eosinophilia and systemic symptoms": 3.772564307265488, "Eosinophilia": 6.687854768100896, "Exposure during pregnancy": 4.472023273172317, "Gamma-glutamyltransferase increased": 3.6155011095293967, "Gastrointestinal haemorrhage": 4.525780544756375, "Haematemesis": 15.21036327493926, "Haematoma": 41.13495550792344, "Haematoma muscle": 75.38139348792014, "Haematuria": 6.903668053939697, "Haemoglobin decreased": 3.8825875924515976, "Haemorrhage": 6.716240857934408, "Haemorrhagic stroke": 12.967585947209905, "Heparin-induced thrombocytopenia": 17.00200692193224, "Hepatic cytolysis": 4.972557145476923, "Inflammation": 2.6184451665575184, "International normalised ratio increased": 4.262828652879841, "Liver injury": 3.9336780650627032, "Melaena": 9.25902644067627, "Mixed liver injury": 32.9126697180814, "Muscle haemorrhage": 77.7148033002511, "Pulmonary embolism": 3.0498742035085766, "Rash maculo-papular": 17.28816975892597, "Rectal haemorrhage": 6.291578025545048, "Septic shock": 6.398672618912167, "Shock haemorrhagic": 55.90311496897804, "Subarachnoid haemorrhage": 13.267803265070238, "Subdural haematoma": 28.4468661081193, "Subdural haemorrhage": 37.39592895397138, "Tendon rupture": 7.886298648816006, "Thrombocytopenia": 5.829039919543996, "Transaminases increased": 4.312729556325913, "Vaginal haemorrhage": 4.369567826302657}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1110.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1110.json
index 7a8d7441e95..2d2f4de0d8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1110.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1110.json
@@ -1 +1 @@
-{"Acute HIV infection ": 280.20277738887563, "Acute hepatitis C ": 27.41597793612541, "Acute kidney injury ": 3.787177161446794, "Albuminuria ": 2.169895356110505, "Anaemia of chronic disease ": 4.215352552502857, "Anhedonia ": 36.234057817902766, "Ankle fracture ": 15.434480687157956, "Anxiety ": 8.144784670968768, "Avulsion fracture ": 9.633760360102928, "Blood HIV RNA increased ": 5.4504545664058295, "Blood creatine increased ": 7.446884595025429, "Blood creatinine abnormal ": 7.110318382294442, "Blood creatinine increased ": 7.88866961075191, "Blood phosphorus decreased ": 6.338317095881918, "Bone demineralisation ": 46.45425171637221, "Bone density abnormal ": 41.5219315712452, "Bone density decreased ": 53.94310226682398, "Bone disorder ": 13.430547128528756, "Bone loss ": 68.51368227584163, "CD4 lymphocytes decreased ": 2.5722120246246014, "Cervical spinal stenosis ": 3.077848270211893, "Cervical vertebral fracture ": 3.1802554862285124, "Chronic kidney disease ": 45.10558066350288, "Chronic kidney disease-mineral and bone disorder ": 30.366109952556187, "Clavicle fracture ": 7.993901502456419, "Compression fracture ": 5.565300872796311, "Craniofacial fracture ": 5.097710488625307, "Creatinine renal clearance decreased ": 2.1369872937570418, "Decreased activity ": 6.27635512038181, "Degenerative bone disease ": 19.51880637956595, "Dental caries ": 4.4449558645243314, "Dysstasia ": 2.3740295489725467, "Economic problem ": 29.370968323767038, "Emotional distress ": 30.04732525117182, "End stage renal disease ": 26.42406254763668, "Fanconi syndrome ": 15.50414219497317, "Fanconi syndrome acquired ": 35.27945908165026, "Fear-related avoidance of activities ": 18.65184844518581, "Femoral neck fracture ": 2.394447525081536, "Femur fracture ": 4.541301329245099, "Fibula fracture ": 15.340182869365684, "Foot fracture ": 19.006097479218766, "Forearm fracture ": 12.351142054677586, "Fracture ": 25.590753011490605, "Fractured coccyx ": 3.232855366542165, "Fractured sacrum ": 6.520159988183859, "Gene mutation identification test positive ": 4.908400027954089, "Genotype drug resistance test positive ": 8.898345177071272, "Glomerular filtration rate abnormal ": 34.19553337255382, "Glomerular filtration rate decreased ": 5.544934713583113, "Glomerular filtration rate increased ": 19.96672116034269, "Glycosuria ": 5.991290921759968, "HIV infection ": 4.125121315088141, "HIV test positive ": 26.20451359067532, "Hand fracture ": 18.44578937706576, "Hepatitis B DNA increased ": 2.323754783340984, "Hip arthroplasty ": 6.418942258890757, "Hip fracture ": 6.635462243554665, "Humerus fracture ": 5.683795462987426, "Hypercreatinaemia ": 4.9373847004101705, "Hyperparathyroidism ": 4.462040415720573, "Hyperparathyroidism secondary ": 12.64441609693646, "Hyperphosphataemia ": 2.016318942228509, "Hyperphosphaturia ": 13.416712855848262, "Hypophosphataemia ": 4.832732673545217, "Immune reconstitution inflammatory syndrome ": 6.012529462054437, "Immune reconstitution inflammatory syndrome associated Kaposi's sarcoma ": 10.352984520321906, "Immune reconstitution inflammatory syndrome associated tuberculosis ": 6.891947290869579, "Intervertebral disc degeneration ": 6.447042394555401, "Intervertebral disc space narrowing ": 5.99790697712559, "Jaw fracture ": 12.156778381114195, "Joint arthroplasty ": 5.742276368623741, "Kidney enlargement ": 2.1221588922214827, "Kidney fibrosis ": 3.869070493460961, "Limb fracture ": 17.986323589381943, "Loss of personal independence in daily activities ": 2.090275867570981, "Lower limb fracture ": 6.635368640602052, "Lumbar spinal stenosis ": 2.290670895721512, "Lumbar vertebral fracture ": 5.651228708380304, "Multiple fractures ": 66.22581992318202, "Nephrogenic anaemia ": 8.653046718866833, "Nephrolithiasis ": 2.6810816813972003, "Nephropathy ": 29.879319102877165, "Osteoarthritis ": 4.618559494639511, "Osteochondrosis ": 2.885117636957224, "Osteomalacia ": 27.71823713318533, "Osteonecrosis ": 60.90031088752984, "Osteopenia ": 39.595588742731046, "Osteoporosis ": 44.003572877467015, "Osteoporotic fracture ": 19.467346146552988, "Pain ": 3.657662426043725, "Partner stress ": 4.124631218771299, "Patella fracture ": 6.244898346236188, "Pathological fracture ": 4.969325355061479, "Pelvic fracture ": 3.904356311281637, "Periodontal disease ": 2.6612894532819773, "Protein total abnormal ": 68.75035750194012, "Protein total increased ": 22.18963464029907, "Protein urine present ": 7.082237197250877, "Proteinuria ": 6.813157290886251, "Quality of life decreased ": 7.574126414369448, "Radius fracture ": 10.440973052944384, "Renal atrophy ": 3.9737051115854354, "Renal cyst ": 3.7235298802991386, "Renal failure ": 22.710740840214225, "Renal function test abnormal ": 2.0454385329692077, "Renal impairment ": 7.677464327746789, "Renal injury ": 42.92517582116043, "Renal transplant ": 5.06634876579056, "Renal tubular acidosis ": 5.421255522672472, "Renal tubular atrophy ": 2.142987850356737, "Renal tubular disorder ": 13.40839534215308, "Renal tubular dysfunction ": 17.296448026875595, "Renal tubular injury ": 5.101837965715749, "Renal tubular necrosis ": 4.684604416254127, "Retrognathia ": 5.59164034990184, "Rib fracture ": 10.124787128807911, "Seroconversion test positive ": 31.856959587365715, "Shoulder arthroplasty ": 3.618436779042909, "Shoulder fracture ": 9.612681412791336, "Sitting disability ": 3.3138221009016453, "Skeletal injury ": 44.38344892571856, "Spinal compression fracture ": 7.638610200442364, "Spinal fracture ": 6.203822384936808, "Spinal osteoarthritis ": 6.650934553243771, "Sternal fracture ": 2.4495776499485835, "Stress fracture ": 2.8758305028396043, "Syphilis ": 4.282063284253092, "Teeth brittle ": 13.802859350777782, "Thoracic vertebral fracture ": 2.7155758793026887, "Tibia fracture ": 16.57487096589126, "Tooth extraction ": 4.667684666002426, "Tooth fracture ": 16.45140878548545, "Tooth loss ": 42.11848744358908, "Ulna fracture ": 9.286609988380077, "Upper limb fracture ": 7.461123161694659, "Vertebral foraminal stenosis ": 6.783656917901483, "Viral load increased ": 4.756791089592164, "Vitamin D deficiency ": 16.546395533804326, "Wrist fracture ": 13.115803347275715}
\ No newline at end of file
+{"Myalgia": 5.535939184449084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1111.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1111.json
index 02194945705..0ce3e972bf3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1111.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1111.json
@@ -1 +1 @@
-{"Acute kidney injury ": 7.50659740576162}
\ No newline at end of file
+{"Accident": 4.669873531604871, "Aneurysm": 5.565974973451828, "Angina unstable": 3.222385191748701, "Aphonia": 8.242549318390695, "Aspiration": 2.74423057262852, "Asthma": 3.36689293301383, "Atrial fibrillation": 3.1694182559585604, "Atrioventricular block": 2.5443485024857275, "Bacterial infection": 2.51043333134109, "Bladder cancer": 2.640474618825832, "Bladder disorder": 3.567330506231302, "Blindness": 2.048993225143641, "Blindness transient": 3.1092662580705035, "Brain neoplasm": 3.277012078842939, "Brain neoplasm malignant": 13.7331505587741, "Bronchiectasis": 3.839627703993459, "Bronchitis": 5.041169914926019, "COVID-19 pneumonia": 3.8394041521537647, "Candida infection": 8.757039720671164, "Cardiac disorder": 3.3422374436465163, "Cardiac failure congestive": 3.11404898263949, "Cardiac flutter": 2.669873505943685, "Cardiac operation": 11.457101893131034, "Cardiac pacemaker insertion": 8.637504772323544, "Cataract": 4.939743372483955, "Cataract operation": 6.588579092662127, "Catheterisation cardiac": 6.093320552163183, "Cerebrovascular accident": 3.229175628701107, "Chemotherapy": 8.959033493368791, "Choking": 26.49731970595423, "Cholecystectomy": 2.328663684654314, "Chronic obstructive pulmonary disease": 43.04840004576747, "Coccidioidomycosis": 38.86176518309615, "Colon cancer": 2.0932265359268567, "Condition aggravated": 3.30122750257379, "Coronary arterial stent insertion": 11.867388191222426, "Coronavirus infection": 11.161086795952944, "Coronavirus test positive": 30.448675424809327, "Cough": 5.054750546152815, "Death": 9.0896564215055, "Dementia": 3.375555344364478, "Dementia Alzheimer's type": 2.3444736695798403, "Device use error": 15.651119439082423, "Diabetes mellitus": 2.336604930260296, "Disability": 3.3710901238957205, "Disease complication": 12.639203456448904, "Dry throat": 4.290083986585406, "Dysphonia": 9.22387747064582, "Dyspnoea": 4.869685212343957, "Dyspnoea exertional": 3.55603363050153, "Dysuria": 4.933036084646602, "Emphysema": 15.789408401476448, "Endotracheal intubation": 3.0452775394850256, "Extra dose administered": 8.90091004749655, "Eye haemorrhage": 3.2798182269059546, "Fall": 2.9109127203925347, "Foreign body in throat": 33.03383072148257, "Frustration tolerance decreased": 2.3491978908640534, "Fungal infection": 2.049104031761188, "Fungal pharyngitis": 86.83023986528065, "Glaucoma": 7.7005673796594385, "Haemoptysis": 2.5630922644881684, "Heart valve replacement": 14.04038006104879, "Hernia repair": 14.3759811462674, "Hip arthroplasty": 3.2806828319985364, "Hip fracture": 8.814922875814164, "Hip surgery": 7.262154816001967, "Hospice care": 13.541043846682433, "Hospitalisation": 13.74446748825085, "Ill-defined disorder": 3.4426616104718577, "Illness": 3.453419055997999, "Inability to afford medication": 30.966167299473625, "Incorrect dose administered": 3.79779340451054, "Increased bronchial secretion": 9.785651922750697, "Intentional dose omission": 3.673420498349929, "Internal haemorrhage": 3.236059739155178, "Intraocular pressure increased": 3.9636939573251295, "Knee arthroplasty": 2.0565848986842274, "Knee operation": 6.9728565203318364, "Labelled drug-disease interaction medication error": 12.204449007643952, "Labelled drug-drug interaction medication error": 5.713092356640655, "Laryngitis": 2.5625749122838184, "Lip blister": 6.987481119380737, "Localised infection": 2.817277096056066, "Lower limb fracture": 3.2840106038882344, "Lower respiratory tract infection": 5.432254136742325, "Lung carcinoma cell type unspecified stage IV": 39.86914384301254, "Lung disorder": 7.438562519042331, "Lung lobectomy": 43.80134819390682, "Lung neoplasm malignant": 27.359607352096564, "Lung operation": 22.896485722515365, "Macular degeneration": 2.612308139962814, "Micturition disorder": 5.215362605872128, "Mouth ulceration": 2.3961128021309275, "Mycobacterium avium complex infection": 9.262850283423733, "Myocardial infarction": 3.23695414779638, "Near death experience": 11.409970443892592, "Neoplasm malignant": 6.840172200504258, "Oesophageal candidiasis": 7.979975030086464, "Oral candidiasis": 7.310189186092027, "Oral discomfort": 3.4765932251351, "Oral fungal infection": 6.1289705429192685, "Oral pain": 2.4979797348347144, "Oropharyngeal candidiasis": 28.24853998070572, "Oropharyngeal discomfort": 3.7675063562238074, "Oxygen saturation abnormal": 7.57712623967994, "Oxygen saturation decreased": 5.154926871027933, "Oxygen therapy": 32.78922614320632, "Pelvic fracture": 2.8030863336355973, "Pneumonectomy": 99.34140171115962, "Pneumonia": 14.006400250755632, "Pneumonia bacterial": 4.493209946447538, "Pneumonia fungal": 4.619843761778647, "Pneumothorax": 8.332092253999074, "Post procedural complication": 2.3833721641399723, "Prescription drug used without a prescription": 10.089143579205649, "Product after taste": 18.564093742256343, "Product complaint": 20.81137847643869, "Product dispensing error": 4.223488242024546, "Product dose omission in error": 4.524498351801718, "Product dose omission issue": 9.280783479256398, "Product prescribing issue": 9.137041115051078, "Product residue present": 2.624912776711418, "Product use in unapproved indication": 3.642966556611981, "Product use issue": 2.0572840434396293, "Product used for unknown indication": 24.470497851304785, "Productive cough": 12.120633956747284, "Prostate cancer": 2.6021955441225035, "Pseudomonas infection": 3.299212319100626, "Pulmonary congestion": 12.502590078334284, "Pulmonary fibrosis": 2.350258167574648, "Pulmonary function test decreased": 5.027332136716083, "Pulmonary mass": 6.803645507795789, "Pulmonary oedema": 2.698971519573068, "Pulmonary pain": 3.932391688170632, "Pulmonary thrombosis": 2.3398603130346225, "Rehabilitation therapy": 30.597670684622624, "Respiration abnormal": 2.2661315987433364, "Respiratory disorder": 2.1565536742881704, "Respiratory failure": 2.586302110750671, "Respiratory tract congestion": 4.384575882807394, "Respiratory tract infection": 2.378655061929241, "Retching": 2.3979612135348294, "Rhinorrhoea": 2.1180682317428574, "Rib fracture": 3.3966645977653016, "Secretion discharge": 11.236796371504065, "Sinus congestion": 2.5125656964924388, "Sinus disorder": 3.6599837268637017, "Sleep disorder due to a general medical condition": 3.2185667326933096, "Small cell lung cancer": 10.904478102673782, "Snoring": 4.024942111467695, "Spinal fracture": 6.00089861119028, "Spinal operation": 2.413270662024885, "Sputum discoloured": 4.375855661394247, "Sputum increased": 8.998570516505719, "Stent placement": 9.641572447898705, "Surgery": 5.102265560077497, "Terminal state": 5.337816408434561, "Therapeutic product effect incomplete": 2.8688196349305906, "Therapy cessation": 11.31147836413404, "Therapy interrupted": 5.816034999439452, "Throat cancer": 12.647496975788384, "Throat irritation": 4.502472057164679, "Tongue blistering": 5.706501766230998, "Tongue coated": 5.26185077474976, "Treatment noncompliance": 2.7858956747110306, "Underdose": 3.143781399968208, "Upper-airway cough syndrome": 3.5237051457832576, "Urinary retention": 13.435829370242526, "Urinary tract disorder": 5.0111191528680274, "Urine flow decreased": 12.110124726686555, "Uterine cancer": 3.343097083018364, "Viral infection": 2.94622891874447, "Vision blurred": 2.676298141292114, "Wheezing": 4.440931772621139, "Wrong technique in device usage process": 69.04004903532625, "Wrong technique in product usage process": 2.313481662650567}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1112.json
index 0bfd8b211c6..63f2842d2c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1112.json
@@ -1 +1 @@
-{"Unevaluable event ": 62.01537255047938}
\ No newline at end of file
+{"Abortion spontaneous": 2.440747150236648, "Abscess": 2.2445423577360937, "Accidental exposure to product": 58.69326288632909, "Ankylosing spondylitis": 2.776067441599327, "Arthritis": 3.6619584120971513, "Autoimmune thyroiditis": 3.5122315450733192, "Basal cell carcinoma": 2.1640253690078675, "Brain injury": 2.1956455292758643, "Breast cancer": 3.50585648379731, "Bronchitis": 2.706802533377124, "COVID-19 pneumonia": 3.300589145769273, "Cardiac operation": 4.714499057431661, "Carpal tunnel syndrome": 2.3578869659440174, "Cellulitis": 6.413235889914261, "Cholecystectomy": 4.80760285122765, "Colon cancer": 2.487419958831538, "Cutaneous T-cell lymphoma": 16.967214135582303, "Cystitis": 2.2067979359127023, "Decreased immune responsiveness": 4.470860084643962, "Dermatitis atopic": 4.440725754656199, "Dermatitis exfoliative generalised": 2.199150991812561, "Device defective": 14.98339610367361, "Device deployment issue": 86.10043408502275, "Device issue": 55.76397629723306, "Device leakage": 45.16241213759934, "Device malfunction": 24.720262477258647, "Device occlusion": 11.79561858675616, "Disability": 3.355216252148965, "Diverticulitis": 3.63600347891442, "Drug delivery system malfunction": 45.03986657516173, "Eczema": 3.8306850009236575, "Eczema nummular": 29.826567259542028, "Endometrial cancer": 25.995582423225635, "Erectile dysfunction": 4.5883559431611625, "Erythrodermic psoriasis": 25.113494033747774, "Exposure during pregnancy": 2.036383649706411, "Gamma-glutamyltransferase increased": 2.576649240824072, "Gastric cancer": 2.302493632626053, "Gastroenteritis": 2.773484033560378, "Gout": 2.410526970313048, "Guttate psoriasis": 30.663619627956813, "Hepatic cirrhosis": 2.2136429894342617, "Hepatitis B": 5.032967976391252, "Hernia": 4.089177018644167, "Herpes virus infection": 4.534687074987334, "Hip surgery": 11.314596563888683, "Hodgkin's disease": 10.787445686135934, "Hyperkeratosis": 4.680366122822149, "Hysterectomy": 6.45624761047756, "Inappropriate schedule of product administration": 3.3047556524211426, "Incorrect route of product administration": 2.452203394120468, "Infection": 2.3022284979815506, "Injection site haemorrhage": 10.528913431687643, "Injection site induration": 2.6825358952367995, "Injection site mass": 2.556052783999356, "Injection site oedema": 4.772554340640084, "Injection site pruritus": 2.066827978498037, "Injection site rash": 2.190408239490503, "Injection site reaction": 3.076832067767031, "Injection site urticaria": 8.703465771276722, "Kidney infection": 4.6220453896305065, "Knee arthroplasty": 6.178566478356277, "Knee operation": 5.67977403312819, "Latent tuberculosis": 22.444994688216635, "Liquid product physical issue": 11.520532976728912, "Liver function test abnormal": 5.19385217883662, "Loss of therapeutic response": 53.95921104168303, "Lymphopenia": 2.043584170517762, "Malignant melanoma": 3.0969463390329564, "Multiple sclerosis": 2.071140049646887, "Mycobacterium tuberculosis complex test positive": 43.97696300973906, "Nail psoriasis": 93.221710785555, "Needle issue": 73.6126439571255, "Nephrolithiasis": 4.386937073744599, "Off label use": 2.460140974227992, "Overweight": 6.107930678714003, "Paternal exposure during pregnancy": 58.38511934966896, "Pemphigoid": 4.183953122795231, "Pneumonia bacterial": 5.597575432780567, "Post procedural complication": 4.920595730716917, "Pregnancy of partner": 96.6072963726104, "Procedural complication": 16.047691533996204, "Product availability issue": 7.885848714305376, "Product complaint": 3.361230663683683, "Product dose omission issue": 25.496949803556475, "Product label issue": 23.865591817840414, "Product leakage": 74.05848220682614, "Product quality issue": 9.743152159918235, "Product storage error": 9.954405049242943, "Product use issue": 2.85666132325604, "Prostate cancer": 5.8682796212515855, "Psoriasis": 56.59049580859468, "Psoriasis area severity index increased": 113.32664811585596, "Psoriatic arthropathy": 95.31260264342576, "Pulmonary tuberculosis": 6.424505021479531, "Pustular psoriasis": 30.30379757164036, "Pustule": 2.6556441451594037, "Respiratory tract infection": 4.388196650206216, "SARS-CoV-2 test positive": 2.473437590364278, "Self-medication": 14.053218824769942, "Skin cancer": 4.763436490286808, "Skin disorder": 2.089648963830132, "Skin exfoliation": 2.7409393965666795, "Skin haemorrhage": 3.192228383502598, "Skin lesion": 2.0874456861897484, "Skin plaque": 5.009081982317691, "Spinal operation": 10.556992227374472, "Squamous cell carcinoma of skin": 5.695430541898567, "Staphylococcal infection": 2.661842215760561, "Surgery": 3.432402771362688, "Syringe issue": 36.80699741563749, "Therapeutic product effect decreased": 2.917886861294342, "Therapeutic response decreased": 6.794238734591018, "Therapeutic response unexpected": 4.627451092286901, "Therapy cessation": 17.12852859954857, "Therapy interrupted": 4.060496267129303, "Therapy non-responder": 2.161102127496895, "Toothache": 2.5852004981788728, "Treatment noncompliance": 2.510377922529676, "Tuberculosis": 10.617560339410833, "Underdose": 18.586390197838718, "Upper respiratory tract infection": 4.529655158257165, "Uterine cancer": 6.167129787376299}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1113.json
index 4a4f5dc5027..0d56c4b6587 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1113.json
@@ -1 +1 @@
-{"Abdominal symptom ": 26.63895069127133, "Acute disseminated encephalomyelitis ": 12.709154182156484, "Allergy to metals ": 31.208132785762515, "Areflexia ": 6.4112930980695575, "Autoimmune disorder ": 2.7644421847759544, "Autoimmune hepatitis ": 4.255827910464643, "Autoimmune thyroiditis ": 10.214820989657216, "Bedridden ": 2.017999925391984, "Chromaturia ": 2.3549682693385887, "Chronic fatigue syndrome ": 13.039041357385424, "Circulatory collapse ": 7.181063100685838, "Coordination abnormal ": 3.5286366255105928, "Demyelination ": 7.087642895744789, "Dermatitis allergic ": 2.642929518840741, "Diarrhoea haemorrhagic ": 2.595402375200736, "Diplopia ": 2.0188113571126785, "Disability ": 4.081461293896608, "Disturbance in attention ": 2.025098108605542, "Dysaesthesia ": 5.055151893154581, "Eczema ": 2.5250214162206124, "Encephalitis ": 6.3053796638871065, "Expired product administered ": 2.4592835847579297, "Extra dose administered ": 6.067105121553268, "Facial pain ": 2.251261880065717, "Facial paresis ": 15.845972085007704, "Formication ": 7.460690967269573, "Gamma-glutamyltransferase increased ": 3.58346641813296, "Gastroenteritis ": 2.66917965920307, "Guillain-Barre syndrome ": 12.979841354061328, "Henoch-Schonlein purpura ": 9.319312592505446, "Hepatic enzyme increased ": 4.959237176846464, "Hepatitis ": 2.3696994369557247, "Hepatitis A ": 97.06904459895983, "Hepatitis A antibody negative ": 982.0740076246668, "Hepatitis B ": 13.811064000770486, "Hepatitis B antibody negative ": 2031.5442067160168, "Hepatitis B surface antibody negative ": 2788.5962976576443, "Hyperventilation ": 2.877268554592895, "Hypoaesthesia ": 2.694438347115633, "Hypokinesia ": 2.02786042749427, "Immunisation reaction ": 2.2139374654013158, "Impaired work ability ": 2.9696472512372623, "Inappropriate schedule of product administration ": 4.583854680225767, "Incomplete course of vaccination ": 22.85280426762973, "Infection susceptibility increased ": 10.598674600215276, "Injected limb mobility decreased ": 4.11674735948964, "Injection site induration ": 3.901989884982667, "Jaundice ": 2.9094060311870744, "Lichen planus ": 7.405725764967803, "Listless ": 5.788596026541258, "Local reaction ": 6.713910802309224, "Meningitis ": 5.9297707516085385, "Monoplegia ": 4.35447158336323, "Motor dysfunction ": 2.4558099113729592, "Movement disorder ": 3.303751596059743, "Mucosal discolouration ": 46.456491910898805, "Multiple sclerosis ": 15.36636396973925, "Muscle twitching ": 2.660815696629773, "Muscular weakness ": 2.952869085412212, "Myelitis ": 16.771831940483228, "Myelitis transverse ": 11.48003730302966, "Myositis ": 4.152910507792303, "Nervous system disorder ": 2.3121264873124527, "Neuralgia ": 2.671330428562546, "Neuritis ": 19.31777602578721, "Neurodermatitis ": 11.963244230239397, "Nystagmus ": 3.983724362663025, "Ocular icterus ": 7.527489952226493, "Optic neuritis ": 12.203871933097796, "Oropharyngeal pain ": 2.029017595718256, "Pain in extremity ": 2.071919380784036, "Pallor ": 4.488031905023656, "Paraesthesia ": 3.211297657009865, "Paralysis ": 4.298732589113557, "Paresis ": 9.11074287435665, "Performance status decreased ": 6.010888894213508, "Peripheral vascular disorder ": 5.822038149731333, "Petechiae ": 2.077163099721941, "Polyarthritis ": 4.854045359640742, "Polyneuropathy ": 4.828480778267172, "Product administered to patient of inappropriate age ": 16.19330497497042, "Product complaint ": 10.298596695916508, "Pulse abnormal ": 5.638753836212602, "Quadriparesis ": 16.515962612042877, "Radiculopathy ": 4.7313983632975045, "Seasonal allergy ": 11.77671855157093, "Sensory disturbance ": 6.242004318535405, "Sensory loss ": 2.6068147951063496, "Somatic symptom disorder ": 10.998725969201692, "Syncope ": 2.440598302052053, "Syringe issue ": 9.7562749112094, "Therapeutic response decreased ": 5.992508170172144, "Therapy non-responder ": 12.093218545721088, "Transaminases increased ": 5.665149905108758, "Underdose ": 13.918380774975006, "Urticaria ": 2.0789633497459845, "Vaccination complication ": 99.80802683284112, "Vaccination site granuloma ": 30.439838249201856, "Vasculitis ": 2.7126668606465723, "Visual field defect ": 3.5164589069405845, "Wrong product administered ": 3.039309237229864}
\ No newline at end of file
+{"Off label use": 4.828821996652227, "Product use in unapproved indication": 11.80852058857483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1114.json
index d066e4181b8..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1114.json
@@ -1 +1 @@
-{"Acute kidney injury ": 5.444873660887693, "Blood pressure increased ": 2.884530671584097, "Confusional state ": 4.128622409048456, "Fall ": 3.248598359130465, "Hyperkalaemia ": 8.554381585502908, "Hypotension ": 2.4071361649815284, "Oedema peripheral ": 12.1722214162604}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1115.json
index b41e83b9f93..7b2d33e7fe0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1115.json
@@ -1 +1 @@
-{"Acute kidney injury ": 4.634730624503439, "Clostridium difficile colitis ": 59.760479895785295, "Diarrhoea ": 2.3042208419744674, "Hepatic enzyme increased ": 7.505495467581143, "Off label use ": 3.511937579469737, "Platelet count decreased ": 10.254892277622377, "Thrombocytopenia ": 6.943590077047926}
\ No newline at end of file
+{"Accidental overdose": 2.629133026650079, "Blood glucose abnormal": 24.776360047796075, "Blood glucose decreased": 21.921608310250704, "Blood glucose fluctuation": 25.668338153576983, "Blood glucose increased": 24.888042923987864, "Device breakage": 19.87153211055292, "Device delivery system issue": 33.95545828507519, "Device failure": 20.800436049713444, "Device information output issue": 99.2502740045125, "Device issue": 16.85370270097791, "Device malfunction": 15.91675563628298, "Diabetes mellitus inadequate control": 27.952348195969947, "Diabetic ketoacidosis": 16.452381771478876, "Diabetic retinopathy": 17.97207452109052, "Disability": 4.774194496862323, "Extra dose administered": 13.955697291618444, "Glycosylated haemoglobin increased": 8.823848630402999, "Hyperglycaemia": 23.6681744650378, "Hypoglycaemia": 44.7046347125016, "Hypoglycaemia unawareness": 55.27004942570008, "Hypoglycaemic coma": 28.57195786486116, "Hypoglycaemic encephalopathy": 55.51729358738868, "Hypoglycaemic seizure": 32.32918555067968, "Hypoglycaemic unconsciousness": 78.90169064170057, "Impaired gastric emptying": 13.909185529945471, "Incorrect dose administered": 2.782628252584127, "Incorrect dose administered by device": 60.85943914980587, "Injection site pruritus": 3.294831200287436, "Intentional overdose": 5.234611420794442, "Ketoacidosis": 5.479056995635643, "Limb injury": 5.232721996930988, "Liquid product physical issue": 29.873395748988624, "Liver function test increased": 2.78190103889884, "Maternal exposure during pregnancy": 2.0996718561273644, "Nephropathy": 4.670488686917671, "Neuropathy peripheral": 2.940043789907846, "Pancreatic carcinoma": 3.7372466413431993, "Premature baby": 2.099053487149799, "Product dispensing error": 5.749580509544384, "Product leakage": 28.015484939838466, "Product physical issue": 37.11796127080368, "Product quality issue": 21.20363348604465, "Product storage error": 9.7622590725407, "Retinopathy": 23.979653994058697, "Road traffic accident": 2.666084860409773, "Suicide attempt": 3.846859307514472, "Therapeutic product effect decreased": 2.215382855872344, "Treatment noncompliance": 4.4978892775475545, "Weight increased": 3.1247752020184443, "Wrong technique in product usage process": 2.4015816251901425}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1116.json
index 49132c2cac6..048ff5150ad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1116.json
@@ -1 +1 @@
-{"Balance disorder ": 4.729869674120376, "Depression ": 2.1450639516135945, "Fall ": 2.775997932755565, "Gait disturbance ": 2.957715467588762, "Multiple sclerosis ": 24.853966529166293, "Multiple sclerosis relapse ": 66.59342900293417, "Muscle spasms ": 3.1020041071496247, "Progressive multifocal leukoencephalopathy ": 116.42808810046051, "Urinary tract infection ": 6.358953737836092}
\ No newline at end of file
+{"Coma": 26.76009390116617, "Completed suicide": 82.87532264830675, "Intentional overdose": 36.2364660944628, "Suicide attempt": 27.074442430164652, "Tachycardia": 12.792767922242176, "Toxicity to various agents": 24.975687897462016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1117.json
index 860c5a28765..ea0d96f2613 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1117.json
@@ -1 +1 @@
-{"Amnesia ": 9.285647470349865, "Chest pain ": 2.3672459175088583, "Chronic obstructive pulmonary disease ": 34.97678144663863, "Cough ": 4.571181945271494, "Disorientation ": 10.887818752596278, "Dyspnoea ": 2.918677390545869, "Emphysema ": 91.47627680376856, "Lower respiratory tract infection ": 13.073612994098845, "Lung disorder ": 12.398510233168937, "Overdose ": 4.575354809980388, "Product use in unapproved indication ": 3.0134787067733884, "Tachycardia ": 2.7656072009510044, "Tachypnoea ": 27.489483313897065}
\ No newline at end of file
+{"Nervous system disorder": 75.2965792521512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1118.json
index c06b9d7c3e4..16acd3be5fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1118.json
@@ -1 +1 @@
-{"Allergy to animal ": 166.09993044314527, "Asthma ": 47.22364410200125, "Atelectasis ": 17.501067722383226, "Blindness ": 4.949239319352478, "Chest discomfort ": 4.950594641698073, "Chronic obstructive pulmonary disease ": 49.250276573397855, "Cough ": 5.220979909334505, "Dry mouth ": 3.662890591879943, "Dust allergy ": 89.86795318643874, "Dysphonia ": 4.420932041634387, "Dyspnoea ": 4.57563122893999, "Dyspnoea exertional ": 9.44955322653682, "Eosinophil count increased ": 147.81126690164493, "Full blood count abnormal ": 36.34621002572706, "Increased bronchial secretion ": 73.64419455231749, "Loss of personal independence in daily activities ": 21.10253761371964, "Lower respiratory tract infection ": 6.289517735241842, "Obstructive airways disorder ": 33.284421332421, "Oral candidiasis ": 9.476668531196724, "Oral pain ": 8.410569975546164, "Oropharyngeal pain ": 2.1055093908729736, "Pneumonia ": 4.014423547748189, "Productive cough ": 18.87535857273193, "Pulmonary congestion ": 20.046673850321056, "Retinitis pigmentosa ": 927.7044778772724, "Seasonal allergy ": 23.92225800505608, "Sleep disorder due to a general medical condition ": 70.11035096154502, "Sputum discoloured ": 24.47563114611425, "Therapeutic product effect incomplete ": 25.33617825864877, "Therapeutic response decreased ": 5.102463532025023, "Wheezing ": 27.58890843966702}
\ No newline at end of file
+{"Acute kidney injury": 2.442187573669816, "Alanine aminotransferase increased": 4.456980771431938, "Aspartate aminotransferase increased": 3.995900329829647, "Differentiation syndrome": 6457.682812330478, "Disseminated intravascular coagulation": 12.92259288965895, "Electrocardiogram QT prolonged": 87.4483537985836, "Febrile neutropenia": 3.919462467594223, "Fluid retention": 7.3652338003123585, "Hepatotoxicity": 7.840642177793671, "Leukocytosis": 16.82479904356629, "Neuropathy peripheral": 7.451612065211512, "Neutropenia": 4.0265529689390185, "Pancytopenia": 4.657562294120532, "Pericardial effusion": 9.680716121109253, "Pleural effusion": 5.043858325778289, "Renal failure": 2.459959758845987, "Ventricular extrasystoles": 15.59342619253204, "Ventricular tachycardia": 19.27148991246068, "Weight increased": 3.089821969972661, "White blood cell count increased": 9.471881009222107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1119.json
index 1713fa56c31..5da657fbe10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1119.json
@@ -1 +1 @@
-{"Cardio-respiratory arrest ": 37.14500927552841, "Completed suicide ": 31.485302076391086, "Death ": 5.054482790600991, "Drug abuse ": 2.931927045546745, "Drug eruption ": 9.09065494289497, "Drug interaction ": 4.422705855266978, "Drug-induced liver injury ": 5.650622068051613, "Intentional overdose ": 4.922599400571227, "Intentional product misuse ": 8.231470919708164, "Loss of consciousness ": 2.245824837892662, "Overdose ": 2.1465761918483364, "Respiratory arrest ": 7.437398555243909, "Stevens-Johnson syndrome ": 6.515991760576148, "Suicide attempt ": 3.3268348105228718, "Toxicity to various agents ": 10.683844269619724}
\ No newline at end of file
+{"Abnormal dreams": 5.403626924150437, "Abortion spontaneous": 2.1855466614040524, "Acute myocardial infarction": 4.364114634545663, "Alanine aminotransferase increased": 2.221817715406452, "Anxiety": 2.5126702817908866, "Blood HIV RNA increased": 94.5397674005564, "Blood creatinine increased": 2.5162463048154478, "Chromaturia": 2.6363422670054346, "Craniofacial fracture": 16.00323880016695, "Cytomegalovirus infection": 4.6028622834965125, "Depressed mood": 4.915513682832467, "Depression": 6.555983005847929, "Dermatitis allergic": 3.777233281008909, "Diabetes mellitus": 2.7495817701500176, "Drug-induced liver injury": 5.912615806000814, "Dyslipidaemia": 9.697881093398912, "Exposure during pregnancy": 2.17369320775612, "Flatulence": 3.035998592875633, "Hepatitis": 3.0237708836892208, "Hepatotoxicity": 2.230755259211301, "Hospitalisation": 3.81080986709355, "Hypertransaminasaemia": 7.174762543246094, "Ill-defined disorder": 2.4291469746753998, "Immune reconstitution inflammatory syndrome": 21.4799484891294, "Insomnia": 7.11788095279899, "Irritability": 2.5451245186720466, "Jaundice": 2.853275251708144, "Lipodystrophy acquired": 12.824058483691358, "Liver function test increased": 2.785495652725661, "Mental disorder": 5.24950614546218, "Mood altered": 3.3596108684714348, "Myocardial infarction": 4.083600852210179, "Nervous system disorder": 2.588420505184052, "Nightmare": 10.760783163387798, "Pancreatitis": 3.15892929738473, "Pancreatitis acute": 2.332336366873145, "Panic attack": 2.3615591326696896, "Psychotic disorder": 3.3703636962415144, "Rhabdomyolysis": 2.276912589685794, "Sleep disorder": 6.430904232321366, "Suicidal ideation": 7.231263881099052, "Suicide attempt": 2.3458293195650377, "Transaminases increased": 4.686827155252556, "Treatment noncompliance": 5.5202989529101085, "Viral load increased": 21.478645110576345, "Virologic failure": 16.189584049400146, "Weight increased": 6.25028232735625}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/112.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/112.json
index 07b78be1192..cd9bf8e2fa3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/112.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/112.json
@@ -1 +1 @@
-{"Cardiomyopathy ": 32.10236724451382, "Completed suicide ": 20.8823279788017, "Constipation ": 2.912677411857183, "Drug abuse ": 17.210980663496287, "Electrocardiogram QT prolonged ": 8.588262012059259, "Hypotension ": 3.8470542251340887, "Intentional overdose ": 8.797260050481878, "Mental impairment ": 26.26973011913314, "Microcytosis ": 2486.398161409357, "Neuroleptic malignant syndrome ": 19.97782218049421, "Overdose ": 6.218184290427175, "Pulmonary oedema ": 24.880606769870635, "Sedation ": 18.927634474977687, "Somnolence ": 2.202478123483944, "Toxicity to various agents ": 24.842176364235915}
\ No newline at end of file
+{"Acute myeloid leukaemia": 83.77124325345295, "Agitation": 7.903658225681238, "Anxiety": 5.906182057917096, "Depression": 3.504193887030684, "Drug interaction": 6.009614643584133, "Drug withdrawal syndrome": 20.446490172271535, "Electrocardiogram QT prolonged": 253.63140734918252, "Hyperhidrosis": 3.787697675690107, "Leukaemia recurrent": 1480.678075625734, "Obsessive thoughts": 438.63740015950617, "Tremor": 3.800906954118714}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1120.json
index 06cb563f961..7bfa7142e2c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1120.json
@@ -1 +1 @@
-{"Cardiac arrest ": 19.10424750165365, "Cardio-respiratory arrest ": 59.97668216800808, "Completed suicide ": 70.40448377862401, "Death ": 8.133131237001775, "Drug abuse ": 11.469858188622805, "Drug interaction ": 3.4856871677443837, "Gastritis ": 5.724904094990235, "Gastrooesophageal reflux disease ": 2.091701002418026, "Intentional overdose ": 4.52359954519825, "Intentional product misuse ": 13.814003587134271, "Medication error ": 4.277647757322662, "Overdose ": 8.639218236813234, "Product administration error ": 5.682825623944992, "Respiratory arrest ": 57.9486603798576, "Suicide attempt ": 3.84377613574144, "Toxicity to various agents ": 2.748323064287948}
\ No newline at end of file
+{"Anaemia": 8.313266069890814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1121.json
index 1825e905616..1826c30cfef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1121.json
@@ -1 +1 @@
-{"Acne ": 118.97330193862942, "Alanine aminotransferase increased ": 2.0501458018937315, "Blood creatine phosphokinase increased ": 15.949778588386271, "Colitis ulcerative ": 6.332032557249201, "Deep vein thrombosis ": 3.000820755386802, "Dermatitis atopic ": 63.92018175252005, "Eczema herpeticum ": 420.7021269661533, "Herpes zoster ": 8.289182462460916, "Lipids increased ": 105.97899889350984, "Off label use ": 6.630244744426442, "Oral herpes ": 14.211142165000236, "Product residue present ": 62.28564945344207, "Pulmonary embolism ": 5.712447604030968, "Skin lesion ": 8.410892218998722, "Therapeutic product effect decreased ": 4.62823904907316, "Therapeutic product effect incomplete ": 2.655454623094807, "Weight increased ": 2.5907508224334217}
\ No newline at end of file
+{"Alopecia": 13.07590007382991, "Anaemia": 4.488328381019586, "Asthenia": 2.682234350171791, "Breast cancer metastatic": 4.112835023218993, "Cholinergic syndrome": 60.423254645511584, "Colitis": 7.717976199434435, "Constipation": 2.9900980141746687, "Cytopenia": 3.51489891633312, "Death": 5.879185040003085, "Diarrhoea": 7.709526807112867, "Disease progression": 61.36476883506372, "Dry skin": 2.035998854606293, "Emotional disorder": 8.24960300324811, "Enteritis": 8.783494134932793, "Extravasation": 14.92973406017034, "Febrile bone marrow aplasia": 51.048881791699, "Febrile neutropenia": 21.01203460348041, "General physical health deterioration": 3.293896312853976, "Haematotoxicity": 8.106610741968414, "Leukopenia": 2.1727495995861696, "Metastases to bone": 4.608094214969409, "Metastases to central nervous system": 31.637125528548697, "Metastases to liver": 11.124902332275592, "Metastases to lymph nodes": 6.426408142046866, "Metastases to meninges": 37.27705422132789, "Metastasis": 15.85493451381507, "Mucosal inflammation": 16.592205532591443, "Myelosuppression": 2.1499986772095654, "Neuropathy peripheral": 2.093101941942096, "Neutropenia": 39.57734005100011, "Neutropenic colitis": 264.3894184690821, "Neutropenic sepsis": 34.953182777898256, "Neutrophil count abnormal": 24.273228276241984, "Neutrophil count decreased": 3.81623650104666, "Pancytopenia": 4.168216564960286, "Pneumonitis": 13.655155478146348, "Sepsis": 2.5141180713781943, "Septic shock": 5.297168415788171, "Stomatitis": 2.156881394561052, "Therapy partial responder": 9.699055877011729, "Thrombocytopenia": 3.6353215470493296, "Triple negative breast cancer": 210.4750744130611}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1122.json
index a66c1e6480e..cb476a522d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1122.json
@@ -1 +1 @@
-{"Condition aggravated ": 2.807826176019775, "Fluid retention ": 14.685715697980688, "Flushing ": 6.437835378927376, "Pain in jaw ": 36.82329903554431, "Pneumonia ": 2.1378429212927093, "Pulmonary arterial hypertension ": 52.96220337989337}
\ No newline at end of file
+{"Abdominal discomfort": 2.9599520689641263, "Abdominal distension": 6.419063795242743, "Abdominal pain": 3.620120907609257, "Abdominal pain upper": 3.685588342464788, "Accidental overdose": 2.658208553952218, "Accidental underdose": 43.03843712659554, "Amylase increased": 11.333830904616011, "Appetite disorder": 2.1474708143991514, "Back disorder": 2.1226926059458373, "Biliary colic": 4.9969585461101165, "Blindness": 2.665281332803318, "Blood glucose abnormal": 10.467575420659744, "Blood glucose decreased": 7.216397246987838, "Blood glucose fluctuation": 2.718203392811243, "Blood glucose increased": 10.073416218937318, "Blood triglycerides increased": 5.552568769330999, "Bowel movement irregularity": 3.267803353671958, "Brain neoplasm": 2.265434111126974, "Breath odour": 13.46262591544766, "Cerebrovascular accident": 2.098509493140566, "Cholecystitis": 3.498049201045728, "Cholecystitis acute": 3.1154684804962995, "Cholelithiasis": 6.044942800254252, "Constipation": 5.051091644598857, "Decreased appetite": 4.660343380325155, "Dehydration": 4.730111486461606, "Dementia": 3.1000158853589075, "Dementia Alzheimer's type": 3.838791649060912, "Diabetes mellitus inadequate control": 6.013370393474809, "Diabetic complication": 6.540771285488041, "Diabetic ketoacidosis": 4.007679780105471, "Diabetic metabolic decompensation": 5.187875080257822, "Diabetic neuropathy": 4.413746809934038, "Diabetic retinopathy": 7.79395430943083, "Diarrhoea": 4.059829506786296, "Dyspepsia": 5.444297239718352, "Eating disorder": 2.22811241881299, "Eructation": 64.50965298380565, "Extra dose administered": 7.982154545373312, "Faeces hard": 6.124392695066311, "Feeding disorder": 10.424494113627816, "Flatulence": 12.78345732995159, "Fluid intake reduced": 4.781537736322375, "Food craving": 8.09562298083101, "Gallbladder disorder": 2.369736299881586, "Gastroenteritis viral": 3.133622734061845, "Gastrointestinal disorder": 4.785727774005438, "Gastrointestinal pain": 2.829708585882691, "Gastrointestinal sounds abnormal": 4.279817904951046, "Gastrooesophageal reflux disease": 4.055070411224713, "Glomerular filtration rate decreased": 4.345697265948747, "Glycosylated haemoglobin abnormal": 14.252844878612102, "Glycosylated haemoglobin decreased": 20.174378131012823, "Glycosylated haemoglobin increased": 28.468341355961996, "Hiccups": 6.6596385647474845, "Hunger": 7.111055611999341, "Hyperlipasaemia": 15.749250667716074, "Hypoglycaemia": 2.7279848811329166, "Hypophagia": 3.879379726599245, "Ileus": 3.914229888618311, "Illness": 3.754518789071537, "Impaired gastric emptying": 22.36237884837358, "Inappropriate schedule of product administration": 2.8026005234367504, "Incorrect dose administered": 5.929511581967992, "Increased appetite": 2.629854708006699, "Injection site bruising": 12.956717524805022, "Injection site discomfort": 5.248700777235031, "Injection site erythema": 5.224260525478492, "Injection site haematoma": 3.0528603582424934, "Injection site haemorrhage": 16.92174243822442, "Injection site hypersensitivity": 32.86994266286161, "Injection site induration": 4.073613948589225, "Injection site injury": 23.00373230491704, "Injection site irritation": 13.961167707962874, "Injection site mass": 16.36851395854585, "Injection site nodule": 6.3388732274982456, "Injection site oedema": 5.714596057391035, "Injection site pain": 2.854430378876262, "Injection site plaque": 30.059265813213, "Injection site pruritus": 14.331781003929477, "Injection site rash": 16.084646214496072, "Injection site reaction": 3.0564400439672155, "Injection site urticaria": 10.22369095720672, "Injection site vesicles": 9.488777453942202, "Injury associated with device": 8.359553808840856, "Intestinal obstruction": 3.9566961672398295, "Ketoacidosis": 3.762546353834728, "Lipase increased": 27.81706180731476, "Medullary thyroid cancer": 50.0158035998072, "Nausea": 3.9137597433277502, "Neoplasm malignant": 3.5067715983238488, "Obstructive pancreatitis": 16.89917769749009, "Pancreatic carcinoma": 8.24885553272093, "Pancreatic carcinoma metastatic": 7.679010726588554, "Pancreatic cyst": 8.842036352729702, "Pancreatic disorder": 13.075804190613146, "Pancreatic enzymes increased": 5.944964742295338, "Pancreatic failure": 13.605000342563953, "Pancreatic mass": 13.502031179557513, "Pancreatitis": 29.629314673776637, "Pancreatitis acute": 12.953750442096418, "Pancreatitis chronic": 5.617763541971441, "Pancreatitis necrotising": 6.181048234022347, "Papillary thyroid cancer": 6.215948186476563, "Product administered at inappropriate site": 8.868154149359322, "Product dose omission issue": 3.738456424015123, "Product storage error": 3.657975720266613, "Regurgitation": 5.142525928562297, "Renal disorder": 2.3396686576733154, "Retching": 2.473882452579214, "Retinal detachment": 2.1693043300112214, "Retinopathy": 3.702058477784784, "Sleep disorder due to general medical condition, insomnia type": 2.4503251544825257, "Small intestinal obstruction": 4.960041638552545, "Thyroid cancer": 11.520853832466871, "Thyroid mass": 5.935347573442068, "Thyroid neoplasm": 20.47303134348697, "Vomiting": 5.505878962868259, "Vomiting projectile": 11.763332078493436, "Weight decreased": 6.563915876721717, "Weight increased": 2.216653586397856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1123.json
index 6c3a9a2fb3a..1f104dd4ef5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1123.json
@@ -1 +1 @@
-{"Diarrhoea ": 2.3992783814738616, "Dizziness ": 3.805618341467909, "Dry mouth ": 14.863619091422716, "Ejaculation delayed ": 278.87763042882534, "Ejaculation disorder ": 182.75982508068552, "Ejaculation failure ": 1366.275005441801, "Erectile dysfunction ": 44.1891832651713, "Fall ": 2.663681338001544, "Gynaecomastia ": 16.825726505283956, "Hypotension ": 3.039503403256823, "Intentional product use issue ": 3.586827280680069, "Libido decreased ": 34.48602214236978, "Nasal congestion ": 46.89901844546527, "Orthostatic hypotension ": 29.556927954910908, "Presyncope ": 4.319022426315292, "Pruritus ": 2.070639017654329, "Rash papular ": 9.14669405834788, "Retrograde ejaculation ": 2970.1814121982547, "Syncope ": 3.7727396840651055, "Testicular pain ": 47.36730823918848, "Urticaria ": 2.0178088753692727, "Vertigo ": 4.662874008234813, "Vision blurred ": 2.223952833161028}
\ No newline at end of file
+{"Loss of consciousness": 26.49912469141836, "Syncope": 22.356207884281368}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1124.json
index 27f4ba3685d..10733cf95bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1124.json
@@ -1 +1 @@
-{"Arthritis ": 5.884095841308956, "Crohn's disease ": 20.95645349985838, "Drug ineffective ": 2.079235180899269, "Off label use ": 2.8436293486532214, "Product use in unapproved indication ": 5.043020370400745, "Psoriasis ": 19.47108059867133, "Psoriatic arthropathy ": 32.492689241697285}
\ No newline at end of file
+{"Acute HIV infection": 280.20277738887563, "Acute hepatitis C": 27.41597793612541, "Acute kidney injury": 3.787177161446794, "Albuminuria": 2.169895356110505, "Anaemia of chronic disease": 4.215352552502857, "Anhedonia": 36.234057817902766, "Ankle fracture": 15.434480687157956, "Anxiety": 8.144784670968768, "Avulsion fracture": 9.633760360102928, "Blood HIV RNA increased": 5.4504545664058295, "Blood creatine increased": 7.446884595025429, "Blood creatinine abnormal": 7.110318382294442, "Blood creatinine increased": 7.88866961075191, "Blood phosphorus decreased": 6.338317095881918, "Bone demineralisation": 46.45425171637221, "Bone density abnormal": 41.5219315712452, "Bone density decreased": 53.94310226682398, "Bone disorder": 13.430547128528756, "Bone loss": 68.51368227584163, "CD4 lymphocytes decreased": 2.5722120246246014, "Cervical spinal stenosis": 3.077848270211893, "Cervical vertebral fracture": 3.1802554862285124, "Chronic kidney disease": 45.10198190313478, "Chronic kidney disease-mineral and bone disorder": 30.366109952556187, "Clavicle fracture": 7.993901502456419, "Compression fracture": 5.565300872796311, "Craniofacial fracture": 5.097710488625307, "Creatinine renal clearance decreased": 2.1369872937570418, "Decreased activity": 6.27635512038181, "Degenerative bone disease": 19.51880637956595, "Dental caries": 4.4449558645243314, "Dysstasia": 2.373478567535961, "Economic problem": 29.370968323767038, "Emotional distress": 30.04732525117182, "End stage renal disease": 26.42406254763668, "Fanconi syndrome": 15.50414219497317, "Fanconi syndrome acquired": 35.27945908165026, "Fear-related avoidance of activities": 18.65184844518581, "Femoral neck fracture": 2.394447525081536, "Femur fracture": 4.541301329245099, "Fibula fracture": 15.340182869365684, "Foot fracture": 19.006097479218766, "Forearm fracture": 12.351142054677586, "Fracture": 25.590753011490605, "Fractured coccyx": 3.232855366542165, "Fractured sacrum": 6.520159988183859, "Gene mutation identification test positive": 4.908400027954089, "Genotype drug resistance test positive": 8.898345177071272, "Glomerular filtration rate abnormal": 34.19553337255382, "Glomerular filtration rate decreased": 5.544934713583113, "Glomerular filtration rate increased": 19.96672116034269, "Glycosuria": 5.991290921759968, "HIV infection": 4.125121315088141, "HIV test positive": 26.20451359067532, "Hand fracture": 18.43026366037598, "Hepatitis B DNA increased": 2.323754783340984, "Hip arthroplasty": 6.418942258890757, "Hip fracture": 6.635462243554665, "Humerus fracture": 5.683795462987426, "Hypercreatinaemia": 4.9373847004101705, "Hyperparathyroidism": 4.462040415720573, "Hyperparathyroidism secondary": 12.64441609693646, "Hyperphosphataemia": 2.016318942228509, "Hyperphosphaturia": 13.416712855848262, "Hypophosphataemia": 4.832732673545217, "Immune reconstitution inflammatory syndrome": 6.012529462054437, "Immune reconstitution inflammatory syndrome associated Kaposi's sarcoma": 10.352984520321906, "Immune reconstitution inflammatory syndrome associated tuberculosis": 6.891947290869579, "Intervertebral disc degeneration": 6.447042394555401, "Intervertebral disc space narrowing": 5.99790697712559, "Jaw fracture": 12.156778381114195, "Joint arthroplasty": 5.742276368623741, "Kidney enlargement": 2.1221588922214827, "Kidney fibrosis": 3.869070493460961, "Limb fracture": 17.986323589381943, "Loss of personal independence in daily activities": 2.090275867570981, "Lower limb fracture": 6.635368640602052, "Lumbar spinal stenosis": 2.290670895721512, "Lumbar vertebral fracture": 5.651228708380304, "Multiple fractures": 66.22581992318202, "Nephrogenic anaemia": 8.653046718866833, "Nephrolithiasis": 2.6806285097701816, "Nephropathy": 29.879319102877165, "Osteoarthritis": 4.618559494639511, "Osteochondrosis": 2.885117636957224, "Osteomalacia": 27.71823713318533, "Osteonecrosis": 60.90031088752984, "Osteopenia": 39.595588742731046, "Osteoporosis": 44.003572877467015, "Osteoporotic fracture": 19.467346146552988, "Pain": 3.6576304018212817, "Partner stress": 4.124631218771299, "Patella fracture": 6.244898346236188, "Pathological fracture": 4.969325355061479, "Pelvic fracture": 3.904356311281637, "Periodontal disease": 2.6612894532819773, "Protein total abnormal": 68.75035750194012, "Protein total increased": 22.18963464029907, "Protein urine present": 7.082237197250877, "Proteinuria": 6.813157290886251, "Quality of life decreased": 7.574126414369448, "Radius fracture": 10.440973052944384, "Renal atrophy": 3.9737051115854354, "Renal cyst": 3.7235298802991386, "Renal failure": 22.710740840214225, "Renal function test abnormal": 2.0454385329692077, "Renal impairment": 7.677464327746789, "Renal injury": 42.92517582116043, "Renal transplant": 5.06634876579056, "Renal tubular acidosis": 5.421255522672472, "Renal tubular atrophy": 2.142987850356737, "Renal tubular disorder": 13.40839534215308, "Renal tubular dysfunction": 17.296448026875595, "Renal tubular injury": 5.101837965715749, "Renal tubular necrosis": 4.684604416254127, "Retrognathia": 5.59164034990184, "Rib fracture": 10.124787128807911, "Seroconversion test positive": 31.856959587365715, "Shoulder arthroplasty": 3.618436779042909, "Shoulder fracture": 9.612681412791336, "Sitting disability": 3.3138221009016453, "Skeletal injury": 44.38344892571856, "Spinal compression fracture": 7.638610200442364, "Spinal fracture": 6.203822384936808, "Spinal osteoarthritis": 6.650934553243771, "Sternal fracture": 2.4495776499485835, "Stress fracture": 2.8758305028396043, "Syphilis": 4.282063284253092, "Teeth brittle": 13.802859350777782, "Thoracic vertebral fracture": 2.7155758793026887, "Tibia fracture": 16.57487096589126, "Tooth extraction": 4.667684666002426, "Tooth fracture": 16.45140878548545, "Tooth loss": 42.11848744358908, "Ulna fracture": 9.286609988380077, "Upper limb fracture": 7.461123161694659, "Vertebral foraminal stenosis": 6.783656917901483, "Viral load increased": 4.756791089592164, "Vitamin D deficiency": 16.546395533804326, "Wrist fracture": 13.115803347275715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1125.json
index f393bb3e6bc..bd5e7964854 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1125.json
@@ -1 +1 @@
-{"Agitation ": 2.680986286067177, "Alanine aminotransferase increased ": 4.613056624396, "Anxiety ": 2.00040030589495, "Aspartate aminotransferase increased ": 3.3985174221568166, "Coma ": 5.05407652742842, "Depression ": 3.380313793476107, "Disorientation ": 7.018722659935164, "Drug interaction ": 4.52546877731131, "Dysarthria ": 6.116331297362772, "Gamma-glutamyltransferase increased ": 10.651416251477333, "Hyperhidrosis ": 2.433444165727105, "Insomnia ": 2.002242225988651, "Intentional overdose ": 30.09070341614108, "Jaundice ": 4.325328430327815, "Mydriasis ": 20.69534154483875, "Restlessness ": 15.997917929639424, "Sedation ": 9.698695654328173, "Serotonin syndrome ": 16.484636612791757, "Sleep disorder ": 3.110988763167674, "Somnolence ": 6.722082735964027, "Suicidal ideation ": 3.434444399055876, "Suicide attempt ": 21.262379493595496, "Tachycardia ": 2.6008157514615013, "Tremor ": 2.8932874883865334}
\ No newline at end of file
+{"Acute kidney injury": 7.50659740576162}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1126.json
index de5c4e96947..fc10c2d0c43 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1126.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.153421264047847, "Angioedema ": 3.918305752864459, "Atrial fibrillation ": 2.922900005109394, "Blood creatinine increased ": 7.221032473508703, "Blood potassium decreased ": 5.013963098025278, "Blood potassium increased ": 21.191445945582103, "Blood pressure abnormal ": 5.105777875797806, "Blood pressure decreased ": 14.610005851876169, "Blood pressure diastolic decreased ": 14.340032255750485, "Blood pressure fluctuation ": 10.071686878996095, "Blood pressure inadequately controlled ": 39.216790828152185, "Blood pressure increased ": 5.348806419371984, "Blood pressure systolic increased ": 3.873286406434437, "Blood urea increased ": 6.219175477943817, "Cardiac failure ": 8.19735253272758, "Cardiac failure chronic ": 66.99707054268391, "Cardiogenic shock ": 4.632575611042719, "Cardiomegaly ": 4.300357683712462, "Colorectal cancer ": 2.0160414758573206, "Diabetes mellitus ": 3.10409808225989, "Dilated cardiomyopathy ": 17.279783813971164, "Dizziness ": 2.4139221138168327, "Ejection fraction decreased ": 25.86129382237018, "Exercise tolerance decreased ": 4.891973175554948, "Glomerular filtration rate decreased ": 12.168385066272046, "Heart rate decreased ": 7.104071597069544, "Hepatic function abnormal ": 2.728084937821881, "Hyperkalaemia ": 22.42117994810287, "Hypertension ": 3.947212109297526, "Hypotension ": 20.038336711355612, "Hypotonia ": 5.939150000865812, "Inappropriate schedule of product administration ": 5.080456742271332, "Infarction ": 9.34408773644059, "Ischaemic cardiomyopathy ": 15.20171955356789, "Left ventricular dysfunction ": 8.835973442662553, "Left ventricular hypertrophy ": 21.03672978620776, "Malignant melanoma ": 4.812103877481853, "Metabolic acidosis ": 2.0510917774333177, "Mitral valve incompetence ": 17.814205263909184, "N-terminal prohormone brain natriuretic peptide increased ": 70.02456107608491, "Oedema ": 3.3354315962276613, "Oedema peripheral ": 3.695945447149588, "Orthopnoea ": 11.50886381992278, "Orthostatic hypotension ": 2.396679803235949, "Peripheral swelling ": 2.191571950742943, "Pollakiuria ": 2.174530238033752, "Prescribed underdose ": 28.444418686658093, "Product use in unapproved indication ": 3.4149383306111605, "Psychotic disorder ": 2.052873492381321, "Pulmonary oedema ": 2.102944257608985, "Renal impairment ": 8.10327250107759, "Respiratory rate increased ": 5.760275060467538, "Sinus bradycardia ": 4.600619571789881, "Tachypnoea ": 4.55760357703481, "Tricuspid valve incompetence ": 8.21231645732534, "Underdose ": 12.660336688721776, "Urine output decreased ": 8.510387614986618, "Ventricular hypokinesia ": 24.023510920868613, "Ventricular tachycardia ": 5.62074393667376, "Wrong technique in product usage process ": 11.534293420904335}
\ No newline at end of file
+{"Unevaluable event": 62.01537255047938}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1127.json
index 15eb37dcdd5..833a269dfe2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1127.json
@@ -1 +1 @@
-{"Drug ineffective ": 14.822806754746676, "Drug ineffective for unapproved indication ": 179.0166295612363, "Off label use ": 10.704645331921489}
\ No newline at end of file
+{"Abdominal symptom": 26.63895069127133, "Acute disseminated encephalomyelitis": 12.709154182156484, "Allergy to metals": 31.208132785762515, "Areflexia": 6.4112930980695575, "Autoimmune disorder": 2.7644421847759544, "Autoimmune hepatitis": 4.255827910464643, "Autoimmune thyroiditis": 10.214820989657216, "Bedridden": 2.017999925391984, "Chromaturia": 2.3549682693385887, "Chronic fatigue syndrome": 13.039041357385424, "Circulatory collapse": 7.181063100685838, "Coordination abnormal": 3.5286366255105928, "Demyelination": 7.087642895744789, "Dermatitis allergic": 2.642929518840741, "Diarrhoea haemorrhagic": 2.595402375200736, "Diplopia": 2.0188113571126785, "Disability": 4.081461293896608, "Disturbance in attention": 2.025098108605542, "Dysaesthesia": 5.055151893154581, "Eczema": 2.5250214162206124, "Encephalitis": 6.3053796638871065, "Expired product administered": 2.4592835847579297, "Extra dose administered": 6.067105121553268, "Facial pain": 2.251261880065717, "Facial paresis": 15.845972085007704, "Formication": 7.460690967269573, "Gamma-glutamyltransferase increased": 3.58346641813296, "Gastroenteritis": 2.66917965920307, "Guillain-Barre syndrome": 12.979841354061328, "Henoch-Schonlein purpura": 9.319312592505446, "Hepatic enzyme increased": 4.959237176846464, "Hepatitis": 2.3696994369557247, "Hepatitis A": 97.06904459895983, "Hepatitis A antibody negative": 982.0740076246668, "Hepatitis B": 13.811064000770486, "Hepatitis B antibody negative": 2031.5442067160168, "Hepatitis B surface antibody negative": 2788.5962976576443, "Hyperventilation": 2.877268554592895, "Hypoaesthesia": 2.694438347115633, "Hypokinesia": 2.02786042749427, "Immunisation reaction": 2.2139374654013158, "Impaired work ability": 2.9696472512372623, "Inappropriate schedule of product administration": 4.583854680225767, "Incomplete course of vaccination": 22.85280426762973, "Infection susceptibility increased": 10.590930765391146, "Injected limb mobility decreased": 4.11674735948964, "Injection site induration": 3.901989884982667, "Jaundice": 2.9094060311870744, "Lichen planus": 7.405725764967803, "Listless": 5.788596026541258, "Local reaction": 6.713910802309224, "Meningitis": 5.9297707516085385, "Monoplegia": 4.35447158336323, "Motor dysfunction": 2.4558099113729592, "Movement disorder": 3.303751596059743, "Mucosal discolouration": 46.456491910898805, "Multiple sclerosis": 15.36636396973925, "Muscle twitching": 2.660815696629773, "Muscular weakness": 2.952869085412212, "Myelitis": 16.771831940483228, "Myelitis transverse": 11.48003730302966, "Myositis": 4.152910507792303, "Nervous system disorder": 2.3121264873124527, "Neuralgia": 2.671330428562546, "Neuritis": 19.31777602578721, "Neurodermatitis": 11.963244230239397, "Nystagmus": 3.983724362663025, "Ocular icterus": 7.527489952226493, "Optic neuritis": 12.203871933097796, "Oropharyngeal pain": 2.029017595718256, "Pain in extremity": 2.071908411498705, "Pallor": 4.48774744077712, "Paraesthesia": 3.211267373662701, "Paralysis": 4.298732589113557, "Paresis": 9.11074287435665, "Performance status decreased": 6.010888894213508, "Peripheral vascular disorder": 5.822038149731333, "Petechiae": 2.077163099721941, "Polyarthritis": 4.854045359640742, "Polyneuropathy": 4.828480778267172, "Product administered to patient of inappropriate age": 16.19330497497042, "Product complaint": 10.298596695916508, "Pulse abnormal": 5.638753836212602, "Quadriparesis": 16.515962612042877, "Radiculopathy": 4.7313983632975045, "Seasonal allergy": 11.77671855157093, "Sensory disturbance": 6.242004318535405, "Sensory loss": 2.6068147951063496, "Somatic symptom disorder": 10.998725969201692, "Syncope": 2.4405646686967493, "Syringe issue": 9.7562749112094, "Therapeutic response decreased": 5.992508170172144, "Therapy non-responder": 12.092154713683705, "Transaminases increased": 5.664801902142974, "Underdose": 13.918380774975006, "Urticaria": 2.0789420262835465, "Vaccination complication": 99.80802683284112, "Vaccination site granuloma": 30.439838249201856, "Vasculitis": 2.7126668606465723, "Visual field defect": 3.5164589069405845, "Wrong product administered": 3.039309237229864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1128.json
index 8c794e48397..d6de81e6853 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1128.json
@@ -1 +1 @@
-{"Diarrhoea ": 2.817387163725226, "Electrocardiogram QT prolonged ": 28.364739606665385}
\ No newline at end of file
+{"Acute kidney injury": 5.43830043297901, "Blood pressure increased": 2.8810042163462177, "Confusional state": 4.123642368160913, "Fall": 3.2445978718206554, "Hyperkalaemia": 8.542893673105524, "Hypotension": 2.404178912241594, "Oedema peripheral": 12.157222485868765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1129.json
index 2d93171aecd..3ab95f35a11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1129.json
@@ -1 +1 @@
-{"Off label use ": 13.726960732971587}
\ No newline at end of file
+{"Acute kidney injury": 4.634730624503439, "Clostridium difficile colitis": 59.760479895785295, "Diarrhoea": 2.30420161316138, "Hepatic enzyme increased": 7.505495467581143, "Off label use": 3.511799260981744, "Platelet count decreased": 10.254892277622377, "Thrombocytopenia": 6.942936907174822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/113.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/113.json
index f40b73f8f8a..6d2d851fe20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/113.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/113.json
@@ -1 +1 @@
-{"Abdominal tenderness ": 5.133888882265375, "Abscess bacterial ": 430.01279390507, "Abscess fungal ": 181.2853996352168, "Activated partial thromboplastin time prolonged ": 3.2819947731632566, "Acute graft versus host disease in skin ": 5.158804254737412, "Acute lymphocytic leukaemia ": 42.91349536039485, "Acute lymphocytic leukaemia recurrent ": 75.60729679708479, "Acute myeloid leukaemia ": 6.873000715560991, "Acute respiratory distress syndrome ": 2.955839166215123, "Adenovirus infection ": 9.183100393507374, "Alanine aminotransferase increased ": 2.427576404015586, "Altered state of consciousness ": 2.185810600706365, "Ammonia increased ": 4.166168267425813, "Amylase increased ": 15.8399167838061, "Anal stenosis ": 241.2498489251392, "Anaphylactoid reaction ": 2.073248773058864, "Angiocentric lymphoma ": 319.67728143141954, "Antithrombin III decreased ": 121.48788414995752, "Aplastic anaemia ": 10.132184254094309, "Ascites ": 2.9117593433638747, "Aspartate aminotransferase increased ": 2.2330382872602685, "Aspergillus infection ": 46.20120275181276, "Atrial septal defect ": 5.094021886965418, "B-cell lymphoma ": 8.670192031147167, "BK virus infection ": 11.791158140462096, "Bacillus test positive ": 276.1900724893627, "Bacteraemia ": 8.94642099772847, "Bacterial infection ": 54.875844041382486, "Bacterial sepsis ": 9.318117569831845, "Bacterial translocation ": 94.27717341224188, "Bilirubin conjugated increased ": 13.61118293712399, "Blast cells present ": 35.1839188335527, "Blood albumin decreased ": 3.48755324015512, "Blood alkaline phosphatase increased ": 3.5001837360849595, "Blood bilirubin increased ": 5.86583937435927, "Blood culture positive ": 13.16169259847029, "Blood fibrinogen decreased ": 17.833106748120954, "Blood growth hormone decreased ": 111.96591464873758, "Blood lactate dehydrogenase increased ": 2.303101354047261, "Blood triglycerides increased ": 2.518795643407307, "Bone marrow failure ": 11.413029748863606, "Brain oedema ": 2.65165890841649, "Bronchopulmonary aspergillosis ": 82.87104268526888, "Cafe au lait spots ": 409.5982213616621, "Candida infection ": 5.918117277077505, "Cardiac ventricular thrombosis ": 33.34410310302302, "Cardiomyopathy ": 2.0773390698575485, "Cardiotoxicity ": 9.010791390349253, "Cellulitis ": 5.528754799572482, "Central hypothyroidism ": 107.35954956553772, "Cerebral cavernous malformation ": 478.4146558212937, "Cerebral haemorrhage ": 2.0193093812864915, "Cerebral ischaemia ": 7.932030498237815, "Cerebral thrombosis ": 10.171756413196482, "Cerebral venous sinus thrombosis ": 13.79892204589274, "Cerebral venous thrombosis ": 68.8207715845906, "Cholestasis ": 4.655123164463696, "Chronic graft versus host disease ": 13.37380877133634, "Chronic sinusitis ": 13.991273260565896, "Clostridium difficile colitis ": 29.462351886900432, "Clostridium difficile infection ": 5.586361099615156, "Coagulopathy ": 7.293560142298391, "Coma hepatic ": 16.583530976311824, "Congenital anomaly ": 5.850741515615895, "Coronavirus infection ": 19.581115861660333, "Cryptorchism ": 34.921023865416814, "Cystitis ": 7.2690700648376225, "Cystitis bacterial ": 710.7920020275193, "Cystitis haemorrhagic ": 6.655472784189851, "Cytomegalovirus chorioretinitis ": 50.82124813042773, "Cytomegalovirus infection ": 3.870452423293704, "Cytomegalovirus viraemia ": 42.33850662187424, "Cytopenia ": 5.341708217348028, "Dacryostenosis acquired ": 43.55443140879772, "Developmental hip dysplasia ": 49.03196797447769, "Device related bacteraemia ": 39.01901747401963, "Device related infection ": 2.736999805130599, "Diffuse alveolar damage ": 115.37471484915706, "Dilated cardiomyopathy ": 5.250312001542403, "Disseminated aspergillosis ": 490.1458222658583, "Disseminated intravascular coagulation ": 4.76279941265032, "Disseminated mucormycosis ": 79.74362905613967, "Drug clearance decreased ": 41.24009998524599, "Drug hypersensitivity ": 2.3654487674411824, "Drug interaction ": 2.0734979320396865, "Ear malformation ": 70.36201745381456, "Ejection fraction decreased ": 2.19611041313432, "Electroencephalogram abnormal ": 13.85665644314401, "Embolism venous ": 10.76203789058176, "Emotional disorder ": 3.212743310736533, "Enamel anomaly ": 73.1880328359359, "Encephalitis ": 18.74000560066149, "Encephalopathy ": 4.697313980582321, "Enteritis ": 37.05199396358634, "Enterobacter infection ": 278.03534902497915, "Enterococcal infection ": 19.15116955114026, "Epilepsy ": 2.3727635501806965, "Eschar ": 25.75877048984337, "Escherichia infection ": 7.496196773771023, "Escherichia sepsis ": 8.326581465317668, "Ewing's sarcoma ": 97.80940640266805, "Febrile neutropenia ": 23.878899281226914, "Foetal distress syndrome ": 14.7398836433327, "Fournier's gangrene ": 3.75999569342926, "Fungaemia ": 18.50180720157124, "Fungal infection ": 16.987797997497495, "Fusarium infection ": 23.475407961537847, "Gastroenteritis norovirus ": 96.65176109842196, "Gastrointestinal necrosis ": 6.965564877225422, "Gastrointestinal perforation ": 4.69816200492505, "Gastrointestinal protozoal infection ": 561.9550542438122, "Generalised tonic-clonic seizure ": 2.338732252311187, "Glioblastoma multiforme ": 76.12593055161321, "Graft versus host disease ": 8.361455674225297, "Growth hormone deficiency ": 42.254489806209534, "Haemangioma ": 22.35483115503358, "Haematotoxicity ": 39.7439864866309, "Haemorrhage intracranial ": 2.268977166156065, "Hemiparesis ": 2.663729352423599, "Hepatic encephalopathy ": 5.06722416348333, "Hepatic failure ": 2.305920437185893, "Hepatic lesion ": 4.453349404255383, "Hepatic steatosis ": 9.348567678525148, "Hepatomegaly ": 6.178761764269764, "Hepatosplenomegaly ": 8.363037532467885, "Hepatotoxicity ": 11.069979152498458, "Herpes simplex ": 4.361995427065136, "Hippocampal sclerosis ": 167.13486459068065, "Human bocavirus infection ": 1957.7473921606545, "Human herpesvirus 6 infection ": 269.4510624146874, "Hyperammonaemia ": 8.296364388840908, "Hyperammonaemic encephalopathy ": 8.295920821338791, "Hyperbilirubinaemia ": 9.86978245559182, "Hyperglycaemia ": 3.2303632958598945, "Hyperlipidaemia ": 6.827131841990698, "Hyperplasia ": 43.44421060422945, "Hypersensitivity ": 2.0417621182635104, "Hypertransaminasaemia ": 5.421282670953528, "Hypertriglyceridaemia ": 39.53357680926413, "Hypoalbuminaemia ": 6.487132446655406, "Hypofibrinogenaemia ": 23.917903852160908, "Hypophagia ": 3.478961303036884, "Hyporeflexia ": 7.198618205930351, "Ileus ": 4.122709627905447, "Ileus paralytic ": 9.51751603334407, "Immune reconstitution inflammatory syndrome ": 2.080511778153732, "Inappropriate antidiuretic hormone secretion ": 8.68460498726035, "Inguinal hernia ": 11.00472420069494, "Intracranial pressure increased ": 6.028169170140573, "Jaundice ": 2.2099360541617314, "Jaundice cholestatic ": 3.580166422718817, "Kidney duplex ": 287.64491534754814, "Klebsiella infection ": 7.15072821700264, "Klebsiella sepsis ": 42.801394379308704, "Lennox-Gastaut syndrome ": 252.46334778932453, "Leptotrichia infection ": 629.9935959036418, "Leukaemia ": 3.2715742746403347, "Leukaemia recurrent ": 39.38746816765458, "Leukoencephalopathy ": 20.430810276701774, "Lip oedema ": 2.200092581512791, "Lipase increased ": 7.399089291530031, "Liver abscess ": 9.19155590411931, "Low birth weight baby ": 4.746422462442229, "Lymphangitis ": 10.827097929273894, "Lymphoid tissue hypoplasia ": 3440.467664101077, "Lymphoma ": 2.085845204885646, "Lymphopenia ": 10.253602836845584, "Magnetic resonance imaging head abnormal ": 15.214867007330565, "Malnutrition ": 3.4388681663165293, "Mental status changes ": 2.221652374359274, "Motor developmental delay ": 65.92066238831329, "Motor dysfunction ": 2.0277978531552314, "Mucormycosis ": 67.07912415846083, "Mucosal inflammation ": 6.362803053901457, "Multiple organ dysfunction syndrome ": 6.308935013096033, "Mycobacterium chelonae infection ": 560.566896846649, "Myelopathy ": 12.887382671684607, "Myelosuppression ": 3.414780689926144, "Myopathy ": 3.482507513095783, "Neoplasm recurrence ": 15.05486522354311, "Neurotoxicity ": 14.2011200632041, "Neutropenia ": 4.752217137987931, "Neutropenic colitis ": 35.58110644337845, "Neutropenic sepsis ": 11.001427394410594, "Non-alcoholic steatohepatitis ": 14.418405644262846, "Norovirus test positive ": 731.7837258096637, "Oesophageal candidiasis ": 31.79229053316334, "Oral herpes ": 11.192740755611666, "Overweight ": 12.29160763943474, "Pancreatic pseudocyst ": 119.01717524869828, "Pancreatitis ": 5.427743888188936, "Pancreatitis acute ": 13.164815233504898, "Pancreatitis necrotising ": 36.922295647503525, "Pancytopenia ": 3.876722608542614, "Panniculitis ": 4.642960968138163, "Papilloedema ": 3.28688134670332, "Parainfluenzae virus infection ": 231.63485125133508, "Paranasal sinus mucosal hypertrophy ": 203.17410242714985, "Partial seizures ": 7.125067755412741, "Peripheral motor neuropathy ": 13.408992819907525, "Peripheral sensory neuropathy ": 3.4635638025119397, "Peritonitis ": 2.3044057099609327, "Phimosis ": 26.63528147586704, "Pleuritic pain ": 4.9786162063403, "Pneumatosis intestinalis ": 113.87109256001396, "Pneumocystis jirovecii pneumonia ": 2.80990899806932, "Pneumonia fungal ": 17.05388200448535, "Posterior reversible encephalopathy syndrome ": 60.56914711338992, "Posture abnormal ": 17.641828859563073, "Prothrombin time prolonged ": 2.426664609599449, "Pseudomonal sepsis ": 319.775220112462, "Pseudomonas infection ": 12.415466277968063, "Pulmonary haemorrhage ": 6.85738638256523, "Pulmonary valve stenosis ": 40.59039606917415, "Pulse absent ": 3.5508766527768394, "Pyelocaliectasis ": 62.71274736489988, "Pyomyositis ": 56.19290957740202, "Renal mass ": 11.9801263927708, "Renal tubular necrosis ": 2.8616712700174745, "Rhinorrhoea ": 2.687526536131911, "Rhinovirus infection ": 102.53648638889446, "Scrotal infection ": 136.08489480916026, "Scrotal oedema ": 22.04026547274284, "Second primary malignancy ": 11.1642737739218, "Secondary immunodeficiency ": 776.0485639878335, "Seizure ": 2.039071835867569, "Sepsis ": 6.1798630716004, "Septic shock ": 9.60473461836865, "Sinusitis fungal ": 34.31395774472666, "Staphylococcal bacteraemia ": 16.095596665461926, "Staphylococcal infection ": 6.086755783066449, "Stenotrophomonas infection ": 18.551315214788676, "Steroid diabetes ": 12.635004786601137, "Stomatitis ": 3.141583824361632, "Superior sagittal sinus thrombosis ": 110.17746461657556, "Systemic candida ": 9.784858006065411, "Systemic mycosis ": 18.281829632326176, "T-cell type acute leukaemia ": 96.109955574952, "Tachypnoea ": 2.87409645787383, "Temporal lobe epilepsy ": 137.07824227255696, "Thymus hypoplasia ": 2467.4379959956373, "Tooth hypoplasia ": 110.99681463570089, "Transverse sinus thrombosis ": 29.499874221664477, "Tumour lysis syndrome ": 10.972282079807687, "Type 1 diabetes mellitus ": 2.793739560365604, "Venoocclusive disease ": 11.276923933617104, "Venoocclusive liver disease ": 59.22517512303188, "Venous thrombosis ": 17.490025553375926, "Venous thrombosis limb ": 3.6051049870984873, "Viraemia ": 119.14962675355363, "Viral haemorrhagic cystitis ": 20.089670572403808, "Viral infection ": 27.161805730258617}
\ No newline at end of file
+{"Condition aggravated": 7.384056038991352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1130.json
index b9fc69c6bff..3e7dd8578a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1130.json
@@ -1 +1 @@
-{"Abnormal dreams ": 24.92171622127777, "Aggression ": 4.815008733020612, "Agitation ": 5.759763586746183, "Anger ": 9.479165282595376, "Anxiety ": 2.288763329920857, "Asthma ": 5.304440306669286, "Completed suicide ": 4.595000183765949, "Condition aggravated ": 3.427877759909617, "Cough ": 2.592262691008745, "Depressed mood ": 14.701112476663232, "Depression ": 5.596001388417595, "Drug-induced liver injury ": 3.2120497651936293, "Dyspepsia ": 2.020503727977837, "Eosinophil count decreased ": 178.9103912301595, "Eosinophil count increased ": 26.621213362331087, "Full blood count abnormal ": 19.295760722661964, "Gastrooesophageal reflux disease ": 10.233667434335215, "Insomnia ": 3.577180527438575, "Irritability ": 9.441155517020963, "Loss of personal independence in daily activities ": 8.131251014982976, "Mania ": 16.873937286848534, "Mood altered ": 7.970782773944391, "Mood swings ": 15.749139610367603, "Nasal obstruction ": 213.2398847970452, "Nightmare ": 6.521673110084333, "Paranoia ": 11.530650983975736, "Productive cough ": 14.740983499543688, "Psychotic disorder ": 8.623899064165924, "Sinusitis ": 12.125655844010716, "Sleep disorder ": 4.82867831410423, "Sleep disorder due to a general medical condition ": 31.60622341915452, "Suicidal ideation ": 12.380166911804343, "Suicide attempt ": 3.321872733562656, "Therapeutic product effect incomplete ": 7.740702146711989, "Throat clearing ": 251.59142101064495, "Treatment noncompliance ": 18.98929197707808, "Upper-airway cough syndrome ": 128.9794377523192, "Vomiting ": 2.05581293590363}
\ No newline at end of file
+{"Balance disorder": 4.629220261873494, "Depression": 2.099411537112582, "Fall": 2.71681783470905, "Gait disturbance": 2.8947067928852968, "Multiple sclerosis": 24.32487228764193, "Multiple sclerosis relapse": 65.17285575728312, "Muscle spasms": 3.0359766631887366, "Progressive multifocal leukoencephalopathy": 113.94990060839072, "Urinary tract infection": 6.223550001655074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1131.json
index ef7aa515287..cc017f065de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1131.json
@@ -1 +1 @@
-{"Cough ": 4.6474506586541455, "Febrile convulsion ": 276.5031654646899, "Seizure ": 7.04383688745487}
\ No newline at end of file
+{"Amnesia": 9.285647470349865, "Chest pain": 2.3672459175088583, "Chronic obstructive pulmonary disease": 34.97678144663863, "Cough": 4.571139547105619, "Disorientation": 10.887818752596278, "Dyspnoea": 2.9186340294021256, "Emphysema": 91.47627680376856, "Lower respiratory tract infection": 13.073612994098845, "Lung disorder": 12.398510233168937, "Overdose": 4.575354809980388, "Product use in unapproved indication": 3.0133847427560143, "Tachycardia": 2.7655373140961053, "Tachypnoea": 27.485574182342447}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1132.json
index e9c635e1c1e..f393362942b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1132.json
@@ -1 +1 @@
-{"Abnormal faeces ": 2.902137949982365, "Acute macular neuroretinopathy ": 3.355011501588046, "Administration site erythema ": 5.1306671196848495, "Administration site hypersensitivity ": 11.701142339144964, "Administration site oedema ": 6.205664932106696, "Administration site pain ": 6.621046934471762, "Administration site reaction ": 2.631533826863067, "Antibody test ": 25.21322444761289, "Antibody test abnormal ": 2.871654462789048, "Antibody test negative ": 3.5645009405434225, "Aortic thrombosis ": 2.153995138068192, "Application site haematoma ": 2.025762746033165, "Application site induration ": 2.7826950218070405, "Application site oedema ": 4.4541578092943865, "Arthralgia ": 2.197046869192503, "Blood fibrinogen increased ": 3.1328476950571247, "Blood pressure measurement ": 2.0452379851995324, "Body temperature ": 3.329747324983579, "Body temperature abnormal ": 3.1710252156394705, "Body temperature increased ": 5.30272117020829, "Body temperature normal ": 10.53434977722905, "Bone pain ": 2.4235343511251, "COVID-19 ": 5.04901041303239, "Capillary fragility ": 2.6565024752590003, "Cerebral thrombosis ": 2.8302999226450063, "Cerebral venous sinus thrombosis ": 7.739945463712981, "Cerebral venous thrombosis ": 3.711956903363014, "Chills ": 5.067167443898866, "Chronic inflammatory demyelinating polyradiculoneuropathy ": 2.3128865262281417, "Encephalomyelitis ": 2.0005163309644427, "Eye haematoma ": 3.9791338003504406, "Eye infarction ": 2.495316970181389, "Eye pain ": 2.3517328425613084, "Eyelid bleeding ": 2.84660536404007, "Eyelid haematoma ": 2.5615433601999325, "Facial discomfort ": 2.7881145802158858, "Fatigue ": 2.073003138679596, "Feeling cold ": 3.4955518953651383, "Feeling hot ": 2.6420538197061214, "Feeling of body temperature change ": 2.359910113607084, "Fibrin D dimer ": 2.706868407105405, "Fibrin D dimer increased ": 3.8280514111739983, "Guillain-Barre syndrome ": 4.132908539748054, "Haemorrhoids thrombosed ": 5.0012562282893, "Head discomfort ": 2.2804921186881777, "Headache ": 3.4656336201849878, "Hemiparaesthesia ": 2.688403272577601, "Heparin-induced thrombocytopenia test positive ": 9.700509811932166, "Hepatic vein thrombosis ": 5.532758799183539, "Hyperaesthesia ": 2.5837965819208826, "Hyperpyrexia ": 2.2518243496536856, "Hypotonia ": 2.7827117143086797, "Incomplete course of vaccination ": 4.794000916064215, "Influenza ": 5.332203974936432, "Influenza like illness ": 4.832881116230317, "Injection site indentation ": 2.347435910299344, "Injection site joint movement impairment ": 3.302547569540732, "Injection site joint pain ": 2.7323034413300613, "Injection site movement impairment ": 4.166269309341488, "Injection site muscle weakness ": 2.011286529984275, "Injection site pain ": 2.215580468971463, "Injection site reaction ": 4.563089401631374, "Jugular vein thrombosis ": 2.3607087248814063, "Labour pain ": 2.405751919591685, "Limb discomfort ": 6.218275209524858, "Local reaction ": 5.362385642871577, "Locomotive syndrome ": 11.810765173396954, "Meningism ": 2.194724300455667, "Mesenteric vein thrombosis ": 2.391820014825808, "Miller Fisher syndrome ": 2.725949081506543, "Myalgia ": 3.301187984473398, "Myelin oligodendrocyte glycoprotein antibody-associated disease ": 3.867124625981779, "Myelitis transverse ": 2.4969514427769828, "New daily persistent headache ": 2.512091163881199, "Nuchal rigidity ": 2.391493760990039, "Ocular discomfort ": 2.284555869215628, "Ophthalmic vein thrombosis ": 4.920479557366775, "Oral contusion ": 2.4642960792907016, "Oxygen saturation ": 6.246853154745332, "Pain in extremity ": 2.8143827402669164, "Pain of skin ": 2.1876963627845334, "Periorbital haemorrhage ": 2.121937026479123, "Peripheral artery thrombosis ": 2.872970538658464, "Peripheral circulatory failure ": 3.2247585286041778, "Peripheral coldness ": 2.170845432192784, "Peripheral vascular disorder ": 3.805579469567367, "Petechiae ": 3.155442149391035, "Phlebitis superficial ": 3.556748867896201, "Polymerase chain reaction positive ": 2.1368049224706964, "Portal vein thrombosis ": 2.553698747838306, "Portosplenomesenteric venous thrombosis ": 6.315673624353204, "Pulmonary pain ": 2.1810521136909298, "Pyrexia ": 4.145350589224831, "Respiratory depth decreased ": 2.4642960792907016, "Rest regimen ": 3.5041590465242423, "Retinal vascular thrombosis ": 2.975279801206809, "Retinal vein thrombosis ": 2.345155594627615, "Reversed hot-cold sensation ": 3.434087229227952, "SARS-CoV-2 antibody test ": 5.869045099237156, "SARS-CoV-2 antibody test negative ": 4.4332254516051215, "SARS-CoV-2 test negative ": 5.015705715630027, "SARS-CoV-2 test positive ": 4.204660628264038, "Sacral pain ": 2.388434177670164, "Sensory disturbance ": 2.476252389051451, "Sensory level abnormal ": 2.902059267636366, "Severe acute respiratory syndrome ": 31.205225252261773, "Shoulder injury related to vaccine administration ": 2.180484506073059, "Sigmoid sinus thrombosis ": 16.215536244593206, "Splenic vein thrombosis ": 2.1277878191710213, "Sudden cardiac death ": 2.194880899304029, "Superficial vein prominence ": 4.7301865873292455, "Superficial vein thrombosis ": 4.312305411734791, "Superior sagittal sinus thrombosis ": 3.813193723787341, "Tenderness ": 2.279778543409945, "Thrombolysis ": 2.767703360290368, "Thrombophlebitis ": 3.074054912604828, "Thrombosis mesenteric vessel ": 2.728329918163163, "Thrombosis with thrombocytopenia syndrome ": 50.984197369119926, "Transverse sinus thrombosis ": 6.056609635218309, "Vaccination failure ": 6.005217261560954, "Vaccination site atrophy ": 9.097066043231184, "Vaccination site bruising ": 3.5712418496683846, "Vaccination site discomfort ": 13.939786945130258, "Vaccination site haematoma ": 7.978883126163369, "Vaccination site hyperaesthesia ": 2.081970808558284, "Vaccination site hypersensitivity ": 7.566582122434965, "Vaccination site induration ": 3.5706906183395297, "Vaccination site inflammation ": 2.2150069467076845, "Vaccination site injury ": 3.206284261144364, "Vaccination site joint movement impairment ": 2.3380835123055044, "Vaccination site joint pain ": 2.758332995726885, "Vaccination site mass ": 2.317020581007881, "Vaccination site movement impairment ": 2.5027258729453004, "Vaccination site nodule ": 2.0588415454860884, "Vaccination site oedema ": 2.44147216210118, "Vaccination site pain ": 3.398860271003768, "Vaccination site paraesthesia ": 2.1647352967108766, "Vaccination site reaction ": 3.3190131160202183, "Vaccination site warmth ": 3.503973865190762, "Varicophlebitis ": 5.845858536952953, "Varicose vein ": 2.522107753004946, "Vascular pain ": 3.003513148479913, "Vasodilatation ": 3.0064311789355886, "Venous thrombosis ": 3.33970476416579, "Venous thrombosis limb ": 3.353986083056314, "Visceral venous thrombosis ": 5.174917890030904}
\ No newline at end of file
+{"Allergy to animal": 165.87961332744771, "Asthma": 47.16064633858293, "Atelectasis": 17.477853689630866, "Blindness": 4.942673602406519, "Chest discomfort": 4.943846497396004, "Chronic obstructive pulmonary disease": 49.18476769189711, "Cough": 5.213991433501147, "Dry mouth": 3.658030223752195, "Dust allergy": 89.7487501433793, "Dysphonia": 4.415066821444231, "Dyspnoea": 4.569471551368235, "Dyspnoea exertional": 9.437011834270232, "Eosinophil count increased": 147.61474342621224, "Full blood count abnormal": 36.297922636280944, "Increased bronchial secretion": 73.5464981200453, "Loss of personal independence in daily activities": 21.074489103658426, "Lower respiratory tract infection": 6.281172982238171, "Obstructive airways disorder": 33.240232575418496, "Oral candidiasis": 9.464098332735691, "Oral pain": 8.399413138773674, "Oropharyngeal pain": 2.1027160252382897, "Pneumonia": 4.0090900211438365, "Productive cough": 18.850293342668937, "Pulmonary congestion": 20.0200781157964, "Retinitis pigmentosa": 926.4739005449812, "Seasonal allergy": 23.8905267024696, "Sleep disorder due to a general medical condition": 70.01718651690337, "Sputum discoloured": 24.443165832476275, "Therapeutic product effect incomplete": 25.302489716408, "Therapeutic response decreased": 5.095694980690195, "Wheezing": 27.55112427440373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1133.json
index 8c1ca44c29e..fc35ff727e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1133.json
@@ -1 +1 @@
-{"Acne ": 7.180639476509835, "Blood magnesium decreased ": 23.500793987521423, "Cerebral infarction ": 2.0934559341406835, "Colon cancer ": 76.09850701164986, "Colorectal cancer metastatic ": 188.6553068742261, "Conjunctivitis ": 13.375080194716892, "Decreased appetite ": 2.19750841807612, "Dermatitis ": 7.497178450670846, "Dermatitis acneiform ": 447.14163840948726, "Diarrhoea ": 2.542156724671877, "Disease progression ": 10.148890727768045, "Dry skin ": 12.709833565517892, "Erythema ": 2.259089108996288, "Febrile neutropenia ": 3.869850089455552, "Folliculitis ": 4.164078951846105, "Gastrointestinal perforation ": 16.415169105565433, "Gastrointestinal toxicity ": 26.317986804612485, "Haematotoxicity ": 20.76880639419742, "Hypocalcaemia ": 8.870293595804027, "Hypomagnesaemia ": 171.51108215756383, "Infusion related reaction ": 3.268563738025764, "Interstitial lung disease ": 25.11126217969301, "Leukopenia ": 2.432230712818792, "Metastases to liver ": 19.326109349843605, "Metastases to lung ": 8.126174606056066, "Mucosal inflammation ": 9.803165973594096, "Myelosuppression ": 2.773139160113045, "Neuropathy peripheral ": 20.40657767676965, "Neurotoxicity ": 23.748500805987835, "Neutropenia ": 5.2416262542579855, "Neutrophil count decreased ": 10.200712657016911, "Palmar-plantar erythrodysaesthesia syndrome ": 3.613964997254565, "Paronychia ": 352.93183242823807, "Polyneuropathy ": 16.7667016003144, "Pulmonary toxicity ": 12.159814541873336, "Rash ": 3.281277092324803, "Rash papular ": 4.626204344969101, "Rash pustular ": 45.27706100547796, "Rectal cancer ": 33.04762335678139, "Skin disorder ": 32.60552939365841, "Skin exfoliation ": 2.359484520363897, "Skin fissures ": 47.82367735227727, "Skin lesion ": 5.616056866047897, "Skin reaction ": 3.559296880273886, "Skin toxicity ": 206.9874088392349, "Skin ulcer ": 5.445784883195207, "Stomatitis ": 17.432560332732237, "Therapy partial responder ": 48.86753638740368, "Thrombocytopenia ": 3.5222322213200257, "Xerosis ": 82.14570575782956}
\ No newline at end of file
+{"Cardio-respiratory arrest": 37.14500927552841, "Completed suicide": 31.485302076391086, "Death": 5.054482790600991, "Drug abuse": 2.931927045546745, "Drug eruption": 9.09065494289497, "Drug interaction": 4.422705855266978, "Drug-induced liver injury": 5.650277691386738, "Intentional overdose": 4.922599400571227, "Intentional product misuse": 8.231470919708164, "Loss of consciousness": 2.245714934866396, "Overdose": 2.1465761918483364, "Respiratory arrest": 7.437398555243909, "Stevens-Johnson syndrome": 6.515991760576148, "Suicide attempt": 3.3268348105228718, "Toxicity to various agents": 10.683844269619724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1134.json
index de5e1e232b4..ae6bb69fe84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1134.json
@@ -1 +1 @@
-{"Abdominal pain ": 4.741973448856593, "Arthritis ": 4.097538891715336, "Colitis ulcerative ": 30.062009106782423, "Condition aggravated ": 3.1888535048955946, "Crohn's disease ": 22.84430573938296, "Diarrhoea haemorrhagic ": 26.865440061831706, "Frequent bowel movements ": 17.89618934955584, "Haematochezia ": 9.751189704630647, "Intestinal obstruction ": 13.852601989038355, "Off label use ": 2.378602407668343, "Pancreatitis ": 3.0795259033172697, "Rectal tenesmus ": 167.032954129367, "Treatment failure ": 5.920606357370708, "Tubulointerstitial nephritis ": 12.044150533428796}
\ No newline at end of file
+{"Cardiac arrest": 19.10424750165365, "Cardio-respiratory arrest": 59.97668216800808, "Completed suicide": 70.40448377862401, "Death": 8.133131237001775, "Drug abuse": 11.469858188622805, "Drug interaction": 3.4856871677443837, "Gastritis": 5.724904094990235, "Gastrooesophageal reflux disease": 2.091701002418026, "Intentional overdose": 4.52359954519825, "Intentional product misuse": 13.814003587134271, "Medication error": 4.27734081669384, "Overdose": 8.639218236813234, "Product administration error": 5.682380424538338, "Respiratory arrest": 57.9486603798576, "Suicide attempt": 3.84377613574144, "Toxicity to various agents": 2.748323064287948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1135.json
index f8e0e3f0764..f65bcd3275e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1135.json
@@ -1 +1 @@
-{"Acute kidney injury ": 4.133161722136973, "Acute respiratory distress syndrome ": 10.874998640123248, "Acute respiratory failure ": 6.444266261739045, "Alanine aminotransferase increased ": 10.411061807185282, "Aspartate aminotransferase increased ": 6.95137114551639, "Blood bilirubin increased ": 2.126614091533756, "Bradycardia ": 27.1104221545622, "Bronchopulmonary aspergillosis ": 12.41388475154058, "COVID-19 ": 4.331611958135347, "COVID-19 pneumonia ": 79.37823305738294, "COVID-19 treatment ": 1780.4834397195566, "Cholestasis ": 6.920885370136371, "Death ": 7.301323382850774, "Diffuse alveolar damage ": 114.90542522580029, "Disseminated intravascular coagulation ": 6.695303413776047, "Drug ineffective ": 2.254505022029357, "Drug-induced liver injury ": 8.380741867219967, "Electrocardiogram QT prolonged ": 2.251513952628348, "Gamma-glutamyltransferase increased ": 5.193114548116566, "Genotype drug resistance test positive ": 29.40038008298592, "Hepatic cytolysis ": 4.614005283067123, "Hepatic enzyme increased ": 4.216169567130054, "Hepatic function abnormal ": 8.918923321155901, "Hepatitis ": 2.9559867798437365, "Hepatocellular injury ": 13.352466463644827, "Hepatotoxicity ": 5.511694354431929, "Hypertransaminasaemia ": 53.03210328347535, "Hypoxia ": 5.687383023688201, "Liver disorder ": 6.838037003637965, "Liver function test abnormal ": 2.9021044936551323, "Liver function test increased ": 6.350322093652966, "Maternal exposure during pregnancy ": 4.3910939728096015, "Mechanical ventilation ": 39.69780482614727, "Multiple organ dysfunction syndrome ": 7.202359625838215, "Off label use ": 2.014205999875532, "Oxygen saturation decreased ": 8.443477208431764, "Pancreatitis acute ": 3.737774416605651, "Pneumonia ": 2.703510660361577, "Pneumonia aspiration ": 18.59509359871149, "Pneumonia bacterial ": 25.596881324023062, "Pneumothorax ": 6.45504451922386, "Recalled product ": 59.5778111170493, "Recalled product administered ": 83.27717717468008, "Renal impairment ": 10.571195892020745, "Respiratory disorder ": 6.433615956628006, "Respiratory failure ": 12.805043378339024, "SARS-CoV-2 test positive ": 15.97268192033812, "Septic shock ": 3.8146225518168895, "Sinus bradycardia ": 85.14390711368713, "Therapeutic response decreased ": 8.776703326529509, "Transaminases increased ": 33.80608144121106, "Treatment failure ": 4.242988779666023}
\ No newline at end of file
+{"Acne": 118.97330193862942, "Alanine aminotransferase increased": 2.0501458018937315, "Blood creatine phosphokinase increased": 15.949778588386271, "Colitis ulcerative": 6.332032557249201, "Deep vein thrombosis": 3.000820755386802, "Dermatitis atopic": 63.92018175252005, "Eczema herpeticum": 420.7021269661533, "Herpes zoster": 8.289182462460916, "Lipids increased": 105.97899889350984, "Off label use": 6.629983491467604, "Oral herpes": 14.211142165000236, "Product residue present": 62.28564945344207, "Pulmonary embolism": 5.712447604030968, "Skin lesion": 8.410892218998722, "Therapeutic product effect decreased": 4.62823904907316, "Therapeutic product effect incomplete": 2.655454623094807, "Weight increased": 2.5907508224334217}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1136.json
index 41a4f1e5fec..257ea66849f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1136.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.66506377757137, "Altered state of consciousness ": 4.04357212866022, "Anaemia ": 3.672016155333727, "Bronchitis ": 3.929137749055732, "Cardiac failure ": 2.960813416272861, "Cardiac failure congestive ": 2.4778059197327957, "Constipation ": 2.5651882661860657, "Deep vein thrombosis ": 2.198939800892246, "Dehydration ": 2.380927971795404, "Disease progression ": 5.665889524991814, "Febrile neutropenia ": 5.169660030664931, "Haemoglobin decreased ": 2.1962973603249503, "Hypotension ": 2.0017096953687905, "Interstitial lung disease ": 2.76094355520009, "Neuropathy peripheral ": 29.672548275760725, "Neutropenia ": 4.662493760235537, "Oedema peripheral ": 2.60668859245986, "Orthostatic hypotension ": 7.054511278530482, "Pancytopenia ": 7.039671369657623, "Peripheral sensory neuropathy ": 29.22554974512547, "Plasma cell myeloma ": 42.29686851612029, "Platelet count decreased ": 5.960080097788925, "Pneumonia ": 3.0151010525220934, "Pneumonitis ": 5.55748686591266, "Sepsis ": 3.580043646147463, "Septic shock ": 4.820167045058219, "Thrombocytopenia ": 6.2444500285199895, "Tumour lysis syndrome ": 22.633976958755504, "White blood cell count decreased ": 2.298869246355656}
\ No newline at end of file
+{"Condition aggravated": 2.8000770212613317, "Fluid retention": 14.6452001081845, "Flushing": 6.420079052225778, "Pain in jaw": 36.72165043494049, "Pneumonia": 2.1319434987573174, "Pulmonary arterial hypertension": 52.81603703721336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1137.json
index 56ac0e6d22d..66dd8d21902 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1137.json
@@ -1 +1 @@
-{"Abdominal pain ": 3.4784539042357245, "Acute kidney injury ": 7.196393711189057, "Angioedema ": 5.602820157227052, "Diarrhoea ": 4.1894846799870615, "Hyperkalaemia ": 4.129412199973573, "Inappropriate schedule of product administration ": 2.2003833446325527, "Lactic acidosis ": 83.63659740336495, "Lipase increased ": 39.6792820680849, "Metabolic acidosis ": 14.374027664108525, "Pancreatic carcinoma ": 8.513084692751528, "Pancreatitis ": 23.734504115941363, "Pancreatitis acute ": 39.9984755530353, "Pemphigoid ": 20.90526843295087, "Renal failure ": 3.589475444829251, "Weight decreased ": 2.7928500003767067, "Wrong technique in product usage process ": 3.9069895667692784}
\ No newline at end of file
+{"Diarrhoea": 2.399258356647173, "Dizziness": 3.805591916220442, "Dry mouth": 14.863619091422716, "Ejaculation delayed": 278.87763042882534, "Ejaculation disorder": 182.75982508068552, "Ejaculation failure": 1366.275005441801, "Erectile dysfunction": 44.1891832651713, "Fall": 2.663613054000413, "Gynaecomastia": 16.825726505283956, "Hypotension": 3.039433129965882, "Intentional product use issue": 3.586827280680069, "Libido decreased": 34.48602214236978, "Nasal congestion": 46.89901844546527, "Orthostatic hypotension": 29.55055470880943, "Presyncope": 4.319022426315292, "Pruritus": 2.0706139356984448, "Rash papular": 9.1456832911718, "Retrograde ejaculation": 2970.1814121982547, "Syncope": 3.772687754660724, "Testicular pain": 47.36730823918848, "Urticaria": 2.0177882020773685, "Vertigo": 4.662874008234813, "Vision blurred": 2.223952833161028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1138.json
index be8cf25872d..6ab048cf15a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1138.json
@@ -1 +1 @@
-{"Adverse event ": 2.1524767072561164, "Arteriovenous fistula operation ": 291.3353824941928, "Blood glucose decreased ": 2.6863316790540908, "Blood magnesium decreased ": 11.610696779373075, "Blood potassium abnormal ": 56.25309808655963, "Blood potassium decreased ": 20.337569614335195, "Blood potassium increased ": 99.879597427072, "Blood pressure abnormal ": 3.57282827245338, "Cardiac disorder ": 3.0578904527014226, "Cardiac failure congestive ": 6.160484277416457, "Cardiac operation ": 23.730704008947303, "Cardiac pacemaker insertion ": 7.452652347562415, "Cataract operation ": 8.733156986795626, "Cellulitis ": 2.204686974173617, "Cerebrovascular accident ": 2.253586628905528, "Constipation ": 11.100229492003235, "Coronavirus infection ": 9.024962822027758, "Death ": 18.584711376729523, "Dehydration ": 3.1049703326345317, "Dialysis ": 180.3347499129436, "End stage renal disease ": 7.336852987913095, "Eye operation ": 25.131552688500403, "Faecaloma ": 19.02855262070299, "Faeces hard ": 26.004480889399872, "Fall ": 3.3885943969551566, "Flatulence ": 7.530204623928852, "Fluid retention ": 4.536391466188369, "Gout ": 3.912958067469365, "Haematochezia ": 2.6906271494039675, "Hip fracture ": 4.809590408597058, "Hospice care ": 109.95741889958036, "Hospitalisation ": 62.73956667455344, "Hypercalcaemia ": 3.483191689112846, "Hyperkalaemia ": 5.958558051814749, "Hypervolaemia ": 14.59895076502313, "Hypomagnesaemia ": 7.97588770792165, "Ill-defined disorder ": 2.848164425155161, "Illness ": 2.835803713512031, "Inappropriate schedule of product administration ": 6.70791792925514, "Infection ": 2.09302967727532, "Intestinal obstruction ": 2.419053203659203, "Leg amputation ": 19.24300274765625, "Limb injury ": 2.5276264457264697, "Localised infection ": 11.274868997110266, "Lower limb fracture ": 5.364909615279473, "Mental status changes ": 2.292959871453379, "Metabolic acidosis ": 4.637132775526004, "Myocardial infarction ": 2.7420414028758637, "Off label use ": 4.022431387005948, "Pericardial effusion ": 2.061419099827796, "Pneumonia ": 4.029757239127397, "Product colour issue ": 27.22284756317718, "Product dose omission in error ": 9.88908215681454, "Product dose omission issue ": 16.37462033626292, "Product physical issue ": 7.1747585753016505, "Product preparation error ": 22.44627072962048, "Product solubility abnormal ": 26.677681737825765, "Product taste abnormal ": 25.202732683878335, "Pulmonary oedema ": 4.81279038444067, "Rehabilitation therapy ": 45.52358652067237, "Renal disorder ": 9.087973656962811, "Renal failure ": 2.843566311214428, "Renal impairment ": 2.8466656304940057, "Renal transplant ": 58.12345243109648, "Spinal operation ": 8.799023127062497, "Stent placement ": 5.932678121856803, "Surgery ": 15.56228087811788, "Thrombosis ": 2.3351573519179567, "Toe amputation ": 22.579026283911684, "Transfusion ": 5.369868749684438, "Treatment noncompliance ": 8.344193946134597, "Unevaluable event ": 3.6204475883416447, "Urinary tract infection ": 4.649251522167996, "Viral infection ": 2.1320334894862145}
\ No newline at end of file
+{"Arthritis": 5.884095841308956, "Crohn's disease": 20.95645349985838, "Drug ineffective": 2.0792198101078845, "Off label use": 2.84351734016196, "Product use in unapproved indication": 5.0428630837882, "Psoriasis": 19.47108059867133, "Psoriatic arthropathy": 32.492689241697285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1139.json
index 801397d971c..53315ea5974 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1139.json
@@ -1 +1 @@
-{"Abdominal distension ": 4.0675649462136025, "Alanine aminotransferase increased ": 10.911000156161284, "Aspartate aminotransferase increased ": 3.2972010100792177, "Cerebral infarction ": 7.658873699605869, "Drug ineffective ": 6.336854370383594, "Drug resistance ": 6.855741903061904, "Dysphagia ": 8.147846033925518, "Hepatic cancer ": 20.873704873934525, "Hepatic function abnormal ": 3.19438945838244, "Hepatitis B ": 66.57821702822208, "Hepatitis B DNA assay positive ": 1966.8875608376236, "Hepatitis B DNA increased ": 801.0197711433434, "Hepatocellular carcinoma ": 23.079483594531577, "Jaundice ": 4.289553151657469, "Lactic acidosis ": 4.63161942658897, "Liver function test increased ": 10.802338272128758, "Maternal exposure during pregnancy ": 2.955896832124799, "Neoplasm malignant ": 4.206086757849832, "Off label use ": 2.3647412003107924, "Osteoporosis ": 2.444969294416385, "Product dispensing error ": 16.39437735989556, "Renal impairment ": 6.653247428899967, "Suspected counterfeit product ": 111.26280859592256, "Transaminases increased ": 7.901622306157551, "Treatment noncompliance ": 9.15822564032372, "Viral load increased ": 72.46452354431024}
\ No newline at end of file
+{"Agitation": 2.680986286067177, "Alanine aminotransferase increased": 4.613056624396, "Anxiety": 2.00040030589495, "Aspartate aminotransferase increased": 3.3985174221568166, "Coma": 5.05407652742842, "Depression": 3.380313793476107, "Disorientation": 7.018722659935164, "Drug interaction": 4.52546877731131, "Dysarthria": 6.116331297362772, "Gamma-glutamyltransferase increased": 10.651416251477333, "Hyperhidrosis": 2.433444165727105, "Insomnia": 2.002242225988651, "Intentional overdose": 30.09070341614108, "Jaundice": 4.325328430327815, "Mydriasis": 20.69534154483875, "Restlessness": 15.99707350382211, "Sedation": 9.698695654328173, "Serotonin syndrome": 16.484636612791757, "Sleep disorder": 3.110988763167674, "Somnolence": 6.722008612988697, "Suicidal ideation": 3.434444399055876, "Suicide attempt": 21.262379493595496, "Tachycardia": 2.60075002161156, "Tremor": 2.893178196003433}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/114.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/114.json
index f6323917ff4..5ea9375e30f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/114.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/114.json
@@ -1 +1 @@
-{"Abortion induced ": 4.153367745355752, "Acute kidney injury ": 2.023765548907209, "Adrenal insufficiency ": 7.97963607195084, "Alanine aminotransferase increased ": 2.505190556668073, "Alcohol abuse ": 6.645046683104713, "Anxiety ": 5.121372204897111, "Aspartate aminotransferase increased ": 2.363250553784149, "Ataxia ": 3.932043254125021, "Atypical mycobacterial infection ": 32.049539420148186, "Blood HIV RNA increased ": 28.761612174353623, "Blood bilirubin increased ": 10.424721826464426, "Blood corticotrophin decreased ": 54.7351435884485, "Blood creatinine increased ": 2.095571234344709, "Blood lactic acid increased ": 11.725825826076662, "Blood phosphorus decreased ": 10.962271197995966, "Blood triglycerides increased ": 6.371910898749496, "CD4 lymphocytes decreased ": 11.57418142665117, "CSF HIV escape syndrome ": 2394.0921920514274, "Caesarean section ": 16.085530684191454, "Calculus urinary ": 12.828423912730242, "Castleman's disease ": 59.106242291052055, "Cholelithiasis ": 3.728836463302295, "Cholestasis ": 2.3912400738544197, "Conduction disorder ": 21.73677903698688, "Cortisol decreased ": 36.988856913248135, "Cushing's syndrome ": 59.02164351161097, "Cushingoid ": 29.346107220391357, "Depression ": 16.76957930501159, "Depression suicidal ": 440.8795870909281, "Depressive symptom ": 237.3642493336832, "Diplegia ": 7.374381317448041, "Diplopia ": 5.372917610885135, "Drug interaction ": 20.133361695912857, "Drug level increased ": 6.197060041964054, "Drug resistance ": 14.086224655416688, "Ergot poisoning ": 132.506042993111, "Eyelid ptosis ": 24.287355271893244, "Fanconi syndrome ": 11.1244362943146, "Fanconi syndrome acquired ": 7.452611426813426, "Feeling jittery ": 8.568371140194829, "Foetal exposure during delivery ": 37.39790382436052, "Foetal exposure during pregnancy ": 5.007473061321599, "Glomerular filtration rate decreased ": 3.497584496241336, "Goitre ": 7.948387479438012, "Graves' disease ": 7.177943039175762, "Haematuria ": 2.4877349703466427, "Haemolytic anaemia ": 4.045967316400072, "Hepatomegaly ": 2.52835779864938, "Herpes simplex ": 9.305501205112126, "Hiatus hernia ": 3.607914616019385, "Hyperbilirubinaemia ": 38.15087120569685, "Hypercholesterolaemia ": 2.43929409792802, "Hyperlipidaemia ": 11.282554201473989, "Hypertriglyceridaemia ": 6.20822825797017, "Hypophosphataemia ": 5.922991596462227, "Immune reconstitution inflammatory syndrome ": 51.91010536837692, "Jaundice ": 12.434209205190912, "Kaposi's sarcoma ": 52.28693377172978, "Labelled drug-drug interaction medication error ": 2.9753748982531047, "Lipoatrophy ": 46.76954413248669, "Lipodystrophy acquired ": 61.83313937217041, "Lipohypertrophy ": 22.06335317116376, "Live birth ": 6.586866486370775, "Loss of personal independence in daily activities ": 6.757673573466355, "Low birth weight baby ": 4.715409218773686, "Maternal exposure during pregnancy ": 4.277587027962828, "Meningitis cryptococcal ": 24.8479624139308, "Mitochondrial toxicity ": 116.3955291996319, "Mycobacterium avium complex infection ": 18.57641566219981, "Nephrolithiasis ": 7.957820034645501, "Nephropathy toxic ": 6.158190605585218, "No adverse event ": 2.2323945196317108, "Normal newborn ": 14.06872212636886, "Ocular icterus ": 11.090474091391656, "Oesophageal candidiasis ": 10.04628461425767, "Oesophageal varices haemorrhage ": 9.80135768428901, "Ophthalmoplegia ": 36.33223870588911, "Opportunistic infection ": 24.38041814153666, "Oropharyngeal candidiasis ": 26.000716492086333, "Paranoia ": 99.48050623294212, "Parkinsonism ": 2.666821968980529, "Pathogen resistance ": 17.206287741141267, "Pelvic pain ": 2.2885052499429435, "Peripheral sensory neuropathy ": 5.237790466362527, "Petit mal epilepsy ": 4.978780549385239, "Pneumocystis jirovecii pneumonia ": 3.2423914012172053, "Premature baby ": 2.871120816341852, "Premature delivery ": 6.813730009955076, "Premature rupture of membranes ": 32.343802528227194, "Prescribed overdose ": 4.220689305099393, "Product use in unapproved indication ": 3.759087506675887, "Progressive multifocal leukoencephalopathy ": 11.761033010294092, "Proteinuria ": 2.731940268553985, "Psychiatric decompensation ": 864.076421109176, "Psychomotor retardation ": 40.67810696512076, "Psychomotor skills impaired ": 301.9021919157425, "Psychotic disorder ": 41.69863048539939, "Rales ": 4.206955054090167, "Renal aplasia ": 32.29630567175754, "Renal colic ": 6.483783072034165, "Renal dysplasia ": 67.53768970241616, "Renal tubular disorder ": 5.917591469883726, "Renal tubular dysfunction ": 18.067675429419836, "Renal tubular necrosis ": 7.597994325723877, "Sinus bradycardia ": 2.189593043333463, "Suicidal ideation ": 13.932797348303165, "Tearfulness ": 274.57716594713185, "Torsade de pointes ": 4.298159269887615, "Treatment failure ": 3.5705765987411344, "Treatment noncompliance ": 9.786167964201455, "Tubulointerstitial nephritis ": 5.016448674455195, "Type 1 diabetes mellitus ": 3.223741427804724, "Viral load increased ": 24.187752007122715, "Viral mutation identified ": 64.9706700637612, "Virologic failure ": 103.92412176085536}
\ No newline at end of file
+{"Anaemia": 2.4003178637361526, "Chronic lymphocytic leukaemia": 162.08569076814533, "Colectomy": 120.38516549874858, "Colitis": 12.539528052800083, "Death": 2.532092513273746, "Disease progression": 4.333681094365547, "Febrile neutropenia": 4.572052119832367, "Flushing": 4.12308805517138, "Gastrooesophageal reflux disease": 5.681558831972588, "Hepatic steatosis": 17.234922817130382, "Infection": 2.7860159443706847, "Infusion related reaction": 14.8457164984654, "Intestinal obstruction": 19.9927447730106, "Neutropenia": 6.518417060985879, "Pneumonia": 4.458591296339398, "Respiratory tract infection": 14.017825957177514, "Sepsis": 10.319379780683096, "Sleep disorder": 3.9228860020879495, "Urticaria": 2.239585825314821}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1140.json
index d999ef46631..1d3671535d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1140.json
@@ -1 +1 @@
-{"Actinic keratosis ": 103.93834272041644, "Acute kidney injury ": 3.710170592924233, "Arthralgia ": 2.4287868704359425, "Disease progression ": 15.302382951721825, "Electrocardiogram QT prolonged ": 10.930756011241996, "General physical health deterioration ": 2.1638242702828627, "Hepatotoxicity ": 10.494100004576406, "Hyperkeratosis ": 100.8274759295399, "Keratoacanthoma ": 997.8325576393898, "Keratosis pilaris ": 695.27951974193, "Malignant neoplasm progression ": 2.600347477976096, "Metastases to central nervous system ": 27.65001307014291, "Panniculitis ": 79.29499705804155, "Photosensitivity reaction ": 36.187932257270695, "Rash ": 3.3507221023393154, "Rash maculo-papular ": 4.550570885456634, "Rash papular ": 10.424398817434218, "Skin papilloma ": 195.36745689367575, "Skin toxicity ": 96.46392986524911, "Squamous cell carcinoma ": 148.64567988873424, "Squamous cell carcinoma of skin ": 116.26438322960816, "Therapeutic response decreased ": 6.2988866555371175, "Toxic epidermal necrolysis ": 8.0105525505254, "Uveitis ": 21.973604597435383}
\ No newline at end of file
+{"Acute kidney injury": 2.153421264047847, "Angioedema": 3.918305752864459, "Atrial fibrillation": 2.9228201652126278, "Blood creatinine increased": 7.221032473508703, "Blood potassium decreased": 5.013963098025278, "Blood potassium increased": 21.191445945582103, "Blood pressure abnormal": 5.105777875797806, "Blood pressure decreased": 14.609529575798229, "Blood pressure diastolic decreased": 14.340032255750485, "Blood pressure fluctuation": 10.071686878996095, "Blood pressure inadequately controlled": 39.216790828152185, "Blood pressure increased": 5.348712396639927, "Blood pressure systolic increased": 3.873286406434437, "Blood urea increased": 6.219175477943817, "Cardiac failure": 8.196602474200903, "Cardiac failure chronic": 66.99707054268391, "Cardiogenic shock": 4.632575611042719, "Cardiomegaly": 4.300357683712462, "Colorectal cancer": 2.0160414758573206, "Diabetes mellitus": 3.10409808225989, "Dilated cardiomyopathy": 17.279783813971164, "Dizziness": 2.413905344148171, "Ejection fraction decreased": 25.86129382237018, "Exercise tolerance decreased": 4.891973175554948, "Glomerular filtration rate decreased": 12.168385066272046, "Heart rate decreased": 7.104071597069544, "Hepatic function abnormal": 2.728084937821881, "Hyperkalaemia": 22.41806732955181, "Hypertension": 3.947171314448001, "Hypotension": 20.03787060190869, "Hypotonia": 5.93851096370049, "Inappropriate schedule of product administration": 5.080456742271332, "Infarction": 9.34408773644059, "Ischaemic cardiomyopathy": 15.20171955356789, "Left ventricular dysfunction": 8.835973442662553, "Left ventricular hypertrophy": 21.03672978620776, "Malignant melanoma": 4.812103877481853, "Metabolic acidosis": 2.0510917774333177, "Mitral valve incompetence": 17.814205263909184, "N-terminal prohormone brain natriuretic peptide increased": 70.02456107608491, "Oedema": 3.3354315962276613, "Oedema peripheral": 3.695854018914859, "Orthopnoea": 11.50886381992278, "Orthostatic hypotension": 2.396163855438834, "Peripheral swelling": 2.191571950742943, "Pollakiuria": 2.174530238033752, "Prescribed underdose": 28.444418686658093, "Product use in unapproved indication": 3.414831736990238, "Psychotic disorder": 2.052873492381321, "Pulmonary oedema": 2.102668079936036, "Renal impairment": 8.10327250107759, "Respiratory rate increased": 5.760275060467538, "Sinus bradycardia": 4.600619571789881, "Tachypnoea": 4.556954985272079, "Tricuspid valve incompetence": 8.21231645732534, "Underdose": 12.660336688721776, "Urine output decreased": 8.510387614986618, "Ventricular hypokinesia": 24.023510920868613, "Ventricular tachycardia": 5.62074393667376, "Wrong technique in product usage process": 11.534293420904335}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1141.json
index f755d86bdc0..42c11f5d4fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1141.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 45.275267894327605, "Acute myeloid leukaemia recurrent ": 31.57815753876872, "Anaemia ": 2.300698703778378, "Autoimmune haemolytic anaemia ": 33.438318546870654, "Blood lactate dehydrogenase increased ": 5.487730788230329, "Blood phosphorus increased ": 19.549374448162773, "Blood test abnormal ": 9.50939809993904, "C-reactive protein increased ": 2.2423657369786785, "COVID-19 ": 2.160652354270927, "COVID-19 pneumonia ": 10.228899579625168, "Chronic lymphocytic leukaemia ": 193.73324655325067, "Chronic lymphocytic leukaemia recurrent ": 195.74492636581317, "Cytopenia ": 28.77747316386831, "Death ": 2.33199452098539, "Drug intolerance ": 5.303852887732111, "Febrile neutropenia ": 7.490228400116724, "General physical health deterioration ": 3.713192362780255, "Hospitalisation ": 3.730798558980714, "Hypercalcaemia ": 5.942842772370103, "Infection ": 6.002955843660029, "Leukopenia ": 3.5229369564159736, "Lymphocyte count increased ": 29.55071079807676, "Multiple organ dysfunction syndrome ": 4.877874921754071, "Neutropenia ": 17.096786469236427, "Off label use ": 20.462934622158564, "Pancytopenia ": 7.634495276913012, "Pneumonia ": 2.5018019681893926, "Product use complaint ": 49.14598022544505, "Respiratory tract infection ": 4.994230510786925, "Richter's syndrome ": 427.98059946162687, "Sepsis ": 4.401901630177815, "Septic shock ": 6.066469106452171, "Splenomegaly ": 9.042304972113335, "Thrombocytopenia ": 6.670853239012609, "Tumour lysis syndrome ": 151.95913557135515, "Unevaluable event ": 5.588489032890303, "White blood cell count increased ": 4.470997287546172}
\ No newline at end of file
+{"Drug ineffective": 14.75306305199378, "Drug ineffective for unapproved indication": 178.18640137573593, "Off label use": 10.65444279646589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1142.json
index 3bbaff9bd09..ef935a2ec18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1142.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 88.63350198770678, "Acute myeloid leukaemia recurrent ": 116.81213716430454, "Agranulocytosis ": 3.4474401026453334, "Anaemia ": 3.4644083730131223, "Autoimmune haemolytic anaemia ": 35.89574560852182, "Blood calcium decreased ": 5.576604509235185, "Blood lactate dehydrogenase increased ": 7.461897343470305, "Blood phosphorus increased ": 35.59914642081516, "Blood potassium increased ": 6.749537019165823, "Blood uric acid increased ": 5.924699836168286, "Bone marrow failure ": 5.440158670275344, "Bone marrow transplant ": 54.07719449791175, "COVID-19 ": 2.110093507661982, "Chronic lymphocytic leukaemia ": 180.39557737416865, "Chronic lymphocytic leukaemia recurrent ": 121.38606270607632, "Cytopenia ": 62.149635967532646, "Disease progression ": 3.74327964526569, "Dysphagia ": 2.0152991192318424, "Febrile neutropenia ": 26.213232806241308, "Fungal infection ": 5.483313093345237, "Haematotoxicity ": 30.873930476153586, "Haemoglobin decreased ": 3.189824601126929, "Haemolysis ": 6.913563576108045, "Haemolytic anaemia ": 3.1415786739025995, "Hypercalcaemia ": 4.06566124306363, "Immune thrombocytopenia ": 2.607625791171775, "Infection ": 8.29623509573242, "Intentional product use issue ": 2.4442210024458744, "Laboratory test abnormal ": 7.153499136707326, "Leukocytosis ": 3.435863819164556, "Leukopenia ": 3.189345365182621, "Lymphocyte count decreased ": 5.189973608480049, "Mantle cell lymphoma ": 81.83991858205871, "Minimal residual disease ": 273.2854754181052, "Multiple organ dysfunction syndrome ": 2.474981630352914, "Myelodysplastic syndrome ": 9.761312109831897, "Myelosuppression ": 17.075808294633024, "Neutropenia ": 22.121534859030067, "Neutropenic sepsis ": 14.671156167849382, "Neutrophil count decreased ": 5.673746679770883, "Off label use ": 10.22599285725362, "Pancytopenia ": 7.896441014530584, "Plasma cell myeloma ": 11.670601936418954, "Platelet count decreased ": 4.590857825768172, "Pleural effusion ": 2.65605544225935, "Pneumonia ": 3.495110506882911, "Pneumonia fungal ": 21.67345627342415, "Product use complaint ": 20.586116624249826, "Richter's syndrome ": 582.5897667451836, "Sepsis ": 5.3263170275447465, "Septic shock ": 4.587452767872904, "Splenomegaly ": 9.377468403728365, "Systemic mycosis ": 124.90642388616382, "Thrombocytopenia ": 8.100238912211708, "Transplant ": 41.37399124678456, "Tumour lysis syndrome ": 219.76394475950687, "Unevaluable event ": 7.551283964943294, "White blood cell count decreased ": 3.4359587230461583, "White blood cell count increased ": 3.7827634789895215}
\ No newline at end of file
+{"Diarrhoea": 2.8173636523463186, "Electrocardiogram QT prolonged": 28.364739606665385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1143.json
index 1667e783b27..935d534c3a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1143.json
@@ -1 +1 @@
-{"Condition aggravated ": 40.60543900168347, "Off label use ": 11.465374247700511}
\ No newline at end of file
+{"Off label use": 13.726420123272106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1144.json
index 0b540347ad0..8d3ab202603 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1144.json
@@ -1 +1 @@
-{"Abdominal pain ": 4.211797262084774, "Constipation ": 16.511806005450712, "Diarrhoea ": 8.472568939081697}
\ No newline at end of file
+{"Abnormal dreams": 24.92171622127777, "Aggression": 4.815008733020612, "Agitation": 5.759763586746183, "Anger": 9.479165282595376, "Anxiety": 2.288763329920857, "Asthma": 5.304440306669286, "Completed suicide": 4.595000183765949, "Condition aggravated": 3.427877759909617, "Cough": 2.592238643858957, "Depressed mood": 14.701112476663232, "Depression": 5.596001388417595, "Drug-induced liver injury": 3.211854017172713, "Dyspepsia": 2.020503727977837, "Eosinophil count decreased": 178.9103912301595, "Eosinophil count increased": 26.621213362331087, "Full blood count abnormal": 19.295760722661964, "Gastrooesophageal reflux disease": 10.233667434335215, "Insomnia": 3.577180527438575, "Irritability": 9.44070437648679, "Loss of personal independence in daily activities": 8.131251014982976, "Mania": 16.873937286848534, "Mood altered": 7.970782773944391, "Mood swings": 15.749139610367603, "Nasal obstruction": 213.2398847970452, "Nightmare": 6.521673110084333, "Paranoia": 11.530650983975736, "Productive cough": 14.740983499543688, "Psychotic disorder": 8.623899064165924, "Sinusitis": 12.125655844010716, "Sleep disorder": 4.82867831410423, "Sleep disorder due to a general medical condition": 31.60622341915452, "Suicidal ideation": 12.380166911804343, "Suicide attempt": 3.321872733562656, "Therapeutic product effect incomplete": 7.740702146711989, "Throat clearing": 251.59142101064495, "Treatment noncompliance": 18.98929197707808, "Upper-airway cough syndrome": 128.9794377523192, "Vomiting": 2.055785199959753}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1145.json
index 0a774401fa8..c7de6de6eff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1145.json
@@ -1 +1 @@
-{"Abnormal dreams ": 3.37318621636723, "Actinic keratosis ": 38.725050026833394, "Acute leukaemia ": 6.87834777051642, "Acute lymphocytic leukaemia ": 6.079314770104907, "Acute myeloid leukaemia ": 18.24100091948522, "Acute myeloid leukaemia recurrent ": 5.551240884017208, "Agitation ": 2.5421991362655345, "Agranulocytosis ": 2.820135410799613, "Alanine aminotransferase increased ": 5.240374653879671, "Altered state of consciousness ": 5.169284655202852, "Anuria ": 2.5166156093434524, "Aspartate aminotransferase increased ": 6.447846263701006, "Aspergilloma ": 54.06000265178909, "Aspergillus infection ": 38.75906954946362, "Bacteraemia ": 2.203077559365195, "Bacterial infection ": 2.1349486394030004, "Bacterial sepsis ": 3.953155004341159, "Bilirubin conjugated increased ": 7.218602277848142, "Blindness ": 2.007358988849574, "Blindness transient ": 2.4104147160362044, "Blood albumin decreased ": 4.080946502366965, "Blood alkaline phosphatase increased ": 10.306379197647791, "Blood beta-D-glucan increased ": 43.70566324897491, "Blood bilirubin increased ": 6.415889435040623, "Blood creatine phosphokinase increased ": 2.763092579095522, "Blood disorder ": 6.716272222252268, "Blood lactate dehydrogenase increased ": 2.3278358521066296, "Blood magnesium decreased ": 2.2536547217379588, "Bowen's disease ": 15.418936800221308, "Bronchopulmonary aspergillosis ": 28.842559591859, "Candida infection ": 2.6185534434078788, "Cardiac failure ": 2.39340949510036, "Cell death ": 6.7742683819065554, "Cheilitis ": 13.293593542138376, "Chloropsia ": 240.6367787300532, "Cholecystitis ": 4.997080445856948, "Cholecystitis acute ": 5.6911204908364255, "Cholestasis ": 17.574682987499127, "Chromatopsia ": 151.94192232343244, "Colour blindness ": 88.04781897278984, "Complications of transplant surgery ": 48.99452248144711, "Confusional state ": 2.358931423938808, "Cystitis haemorrhagic ": 2.06393136575977, "Deafness bilateral ": 6.348587119684815, "Death ": 2.669613913128396, "Delirium ": 16.57086471565189, "Delusion ": 3.317644910641018, "Dermatitis bullous ": 3.936563750137501, "Dermatitis exfoliative ": 6.396929270622333, "Dermatitis exfoliative generalised ": 5.70596912895872, "Device related infection ": 2.1858518328362457, "Diabetes insipidus ": 3.328160182644789, "Diplopia ": 4.40832791286407, "Disease progression ": 2.9561710220176187, "Disease recurrence ": 3.626196944954191, "Disorganised speech ": 73.83885576482369, "Disorientation ": 2.828792059725842, "Disseminated intravascular coagulation ": 2.297007224643392, "Drug eruption ": 2.138180879813949, "Drug interaction ": 3.0153699861226984, "Drug level above therapeutic ": 13.726665512693025, "Drug level below therapeutic ": 24.51036620670869, "Drug level decreased ": 14.051209239510868, "Drug level increased ": 21.36679761681834, "Drug-induced liver injury ": 4.810024743867458, "Dyschromatopsia ": 73.01145294112155, "Dysphoria ": 9.36907865211444, "Electrocardiogram QT prolonged ": 4.520858977192903, "Encephalopathy ": 3.658346186714437, "Erythropsia ": 117.60732539112094, "Febrile bone marrow aplasia ": 7.414685828411019, "Fluorosis ": 93.42640505607532, "Fungal infection ": 8.529956703517415, "Gallbladder disorder ": 3.3904163348875427, "Gamma-glutamyltransferase increased ": 13.004802692565416, "Graft versus host disease ": 5.906064883103782, "Haemoptysis ": 4.06263832952699, "Haemorrhagic diathesis ": 2.1958086240305077, "Hallucination ": 39.9247386582293, "Hallucination, auditory ": 21.164207312631717, "Hallucination, visual ": 59.75643232354208, "Hallucinations, mixed ": 8.80196688735411, "Halo vision ": 187.24760436163928, "Hepatic cytolysis ": 8.46995234714188, "Hepatic enzyme abnormal ": 3.046953638345157, "Hepatic enzyme increased ": 4.599830115668609, "Hepatic failure ": 3.494106102942393, "Hepatic function abnormal ": 14.997091955294549, "Hepatitis ": 3.4170283704533717, "Hepatitis cholestatic ": 4.177332069915817, "Hepatitis fulminant ": 5.112324998761247, "Hepatocellular injury ": 7.0048517636798895, "Hepatotoxicity ": 5.125883905380617, "Hip fracture ": 2.136264593125449, "Hyperbilirubinaemia ": 2.196505667397472, "Hypokalaemia ": 2.1022499276429425, "Hypomagnesaemia ": 2.216409683302376, "Illusion ": 9.487251932704591, "Immune system disorder ": 2.1204680461567063, "Immunosuppressant drug level increased ": 17.888887628932846, "Inappropriate antidiuretic hormone secretion ": 5.696799664278896, "Jaundice cholestatic ": 4.736084577014103, "Lentigo ": 48.173506867500194, "Leukaemia ": 30.19362380106578, "Leukaemia recurrent ": 21.148782131931178, "Lip blister ": 5.656052732896853, "Liver disorder ": 7.066124976710237, "Liver function test abnormal ": 11.760859097941418, "Liver function test increased ": 8.88344458378139, "Liver injury ": 5.682750917640966, "Logorrhoea ": 6.288063181292692, "Lung disorder ": 2.878510798951254, "Lung transplant rejection ": 39.83635048862307, "Meningitis ": 2.337675901633092, "Mental disorder ": 8.103742127294886, "Mixed liver injury ": 4.071292260662628, "Mucormycosis ": 16.050312198702812, "Multiple organ dysfunction syndrome ": 2.560230636961792, "Myelodysplastic syndrome ": 4.260659062728707, "Neoplasm malignant ": 2.626276122262664, "Neoplasm recurrence ": 5.898440360400695, "Neurotoxicity ": 2.245860206919485, "Optic neuritis ": 5.216255483140998, "Optic neuropathy ": 4.908754258348037, "Pancytopenia ": 2.463818572158823, "Papilloedema ": 9.290576519719766, "Periostitis ": 30.14666225107935, "Persecutory delusion ": 4.118966244746465, "Photophobia ": 13.445438039419347, "Photopsia ": 14.82579612203931, "Photosensitivity reaction ": 31.180583209106384, "Pneumonia ": 2.8129789133751872, "Pneumonia bacterial ": 6.087437432974514, "Pneumonia fungal ": 39.69545904632764, "Product dispensing error ": 2.652762511189472, "Protein total decreased ": 4.426889385910149, "Prothrombin time prolonged ": 3.4019035480767585, "Pseudomembranous colitis ": 4.923921244898617, "Pseudoporphyria ": 128.6672897321775, "Psychiatric symptom ": 4.058998513201081, "Pulmonary haemorrhage ": 3.072916918495556, "Renal disorder ": 2.286695167797914, "Renal impairment ": 5.00017779111373, "Respiratory failure ": 3.3649479216381346, "Restlessness ": 3.5786289372958136, "Retinal haemorrhage ": 6.022153089526001, "Rhabdomyolysis ": 3.031479370740858, "Sepsis ": 2.1529493453502258, "Sinus arrest ": 3.929971468899817, "Skin cancer ": 7.806541663947764, "Skin exfoliation ": 2.395845571748475, "Sleep talking ": 19.60036207220623, "Speech disorder ": 2.146992894476139, "Squamous cell carcinoma ": 12.31691794009347, "Squamous cell carcinoma of skin ": 34.13045195402731, "Stevens-Johnson syndrome ": 2.270270184655644, "Stupor ": 2.255989659425053, "Sunburn ": 15.33528110313298, "Torsade de pointes ": 6.103977272232234, "Toxic epidermal necrolysis ": 2.7803196286874434, "Transaminases increased ": 5.7695527665362185, "Transplant rejection ": 3.4586118534115737, "Ventricular extrasystoles ": 4.020654006826653, "Ventricular fibrillation ": 3.5179796227732254, "Ventricular tachycardia ": 2.8414237504908613, "Vision blurred ": 6.3972850685998495, "Visual acuity reduced ": 5.0568752964547246, "Visual brightness ": 37.90209187304908, "Visual field defect ": 4.902048195383463, "Visual impairment ": 8.021913558434237, "Vitreous floaters ": 2.7677161556824275, "Xanthopsia ": 271.5953308578652}
\ No newline at end of file
+{"Cough": 4.647407556925456, "Febrile convulsion": 276.4066738147391, "Seizure": 7.04305611684988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1146.json
index 0d929124a25..beeca72c82e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1146.json
@@ -1 +1 @@
-{"Accident ": 9.273741952947256, "Accident at work ": 26.149745521403563, "Accidental exposure to product by child ": 4.213169256520356, "Acquired immunodeficiency syndrome ": 11.27570503361228, "Actinic keratosis ": 5.148200600517941, "Acute myocardial infarction ": 3.071445946813132, "Alcohol interaction ": 5.777872679256765, "Amnesia ": 2.182108693692677, "Aneurysm ": 6.2984258876672055, "Angina pectoris ": 2.8959427574340846, "Angiopathy ": 5.424495460314242, "Ankle fracture ": 2.8047186156148074, "Anorgasmia ": 26.84877206451416, "Aortic aneurysm ": 3.35385269780366, "Arterial occlusive disease ": 6.504272692991568, "Arthropathy ": 2.790431530259921, "Asthenopia ": 3.332223315647417, "Back disorder ": 16.732121240186682, "Back injury ": 5.270025736972341, "Basal cell carcinoma ": 2.3212879676148157, "Benign prostatic hyperplasia ": 8.661753688545563, "Bipolar disorder ": 2.4014734358127616, "Blindness ": 13.731050790795852, "Blindness transient ": 7.056607911421479, "Blindness unilateral ": 14.988245792219963, "Blood cholesterol increased ": 2.724478952654246, "Blood pressure abnormal ": 3.187241642929831, "Blood pressure decreased ": 2.1380259322970727, "Blood testosterone abnormal ": 40.49493697391148, "Blood testosterone decreased ": 27.847725306035787, "Blood urine present ": 3.7674588622550753, "Body height decreased ": 3.0738442587627364, "Brain injury ": 5.539057401403409, "Cardiac disorder ": 3.807353323229152, "Cardiac valve disease ": 2.673370455057589, "Carotid artery disease ": 12.715402064002356, "Cataract ": 4.892272306849099, "Central serous chorioretinopathy ": 36.12022254020403, "Cerebral infarction ": 2.6578668777137664, "Cerebrovascular accident ": 4.845752750982413, "Cerebrovascular disorder ": 7.518862846846932, "Cervical vertebral fracture ": 8.823489078847313, "Chloropsia ": 193.30419561825585, "Chondropathy ": 9.134824202803769, "Chromatopsia ": 38.11186535611529, "Colon cancer ": 3.565595403451879, "Colour blindness ": 13.773448885603768, "Concussion ": 3.0928681978910766, "Conjunctival haemorrhage ": 2.417908368677417, "Coronary artery disease ": 2.5426195759498254, "Coronary artery occlusion ": 3.917861189597612, "Coronary artery stenosis ": 2.757629495168243, "Counterfeit product administered ": 20.12346273094249, "Craniofacial fracture ": 3.734543129463785, "Cyanopsia ": 706.0198119716691, "Deafness ": 10.85084725184446, "Deafness neurosensory ": 4.574890635439518, "Deafness transitory ": 18.932642715529937, "Deafness unilateral ": 12.43748808646233, "Death ": 2.539503134301037, "Dementia Alzheimer's type ": 3.2188180739151204, "Diabetes mellitus ": 9.954056173480808, "Diabetic neuropathy ": 2.0076102337676547, "Diabetic retinopathy ": 2.106208176336417, "Diplopia ": 2.652691510145827, "Disturbance in sexual arousal ": 22.110168688848745, "Drug effective for unapproved indication ": 5.650401654667255, "Drug ineffective ": 2.676513772145808, "Dyschromatopsia ": 19.35378657567842, "Dysuria ": 5.3868097707135405, "Ejaculation delayed ": 26.15578811039196, "Ejaculation disorder ": 179.48332459765524, "Ejaculation failure ": 44.64907448214492, "Erectile dysfunction ": 14.16841436152582, "Erection increased ": 5881.196160640347, "Exostosis ": 2.030754037177817, "Expired product administered ": 4.4169697621793125, "Exposure via partner ": 32.05030219137888, "Extra dose administered ": 6.469810207809299, "Eye disorder ": 4.273283090443046, "Eye haemorrhage ": 4.327113849497902, "Flushing ": 4.921538864250029, "Fracture of penis ": 18.65750474614494, "Frustration tolerance decreased ": 2.4516875379082688, "Gallbladder disorder ": 2.3174803065703093, "Genital hypoaesthesia ": 43.04346605830896, "Glaucoma ": 6.628713638373988, "HIV infection ": 4.956590106852047, "HIV test positive ": 15.282436861438102, "Haematospermia ": 56.93989320388568, "Haemorrhage urinary tract ": 4.050255366374707, "Hemiplegia ": 2.741192564062448, "Hernia ": 10.39443850190733, "Hypoacusis ": 9.31538317451052, "Incorrect dose administered ": 3.2826734037158976, "Infarction ": 5.120376813198256, "Intentional product misuse ": 8.308365312393084, "Intentional product use issue ": 3.238322798031636, "International normalised ratio abnormal ": 2.836846714200943, "Intervertebral disc degeneration ": 2.516620130317171, "Intervertebral disc disorder ": 4.108976633062696, "Intervertebral disc protrusion ": 5.250956694623164, "Intraocular pressure increased ": 3.578398270193223, "Joint dislocation ": 2.0967742615893536, "Large intestine polyp ": 2.0837684194102715, "Lentigo maligna ": 177.21213866619368, "Libido decreased ": 2.5741502400427145, "Libido increased ": 9.50189564743061, "Limb injury ": 3.9514352262055614, "Low density lipoprotein increased ": 2.413573988820143, "Lower limb fracture ": 5.199416524804963, "Macular degeneration ": 2.66454131234433, "Macular hole ": 12.44629385977021, "Macular oedema ": 9.445230570750857, "Male orgasmic disorder ": 52.14127593129213, "Male reproductive tract disorder ": 33.506478751547284, "Malignant melanoma ": 186.55452091965492, "Malignant melanoma in situ ": 304.06768829500163, "Malignant melanoma stage I ": 74.9636904094196, "Malignant melanoma stage II ": 108.97182328947208, "Malignant melanoma stage III ": 115.61467380398553, "Malignant melanoma stage IV ": 116.42887587058576, "Meniscus injury ": 4.307880722785227, "Metamorphopsia ": 5.967008577651318, "Metastases to lymph nodes ": 3.624636339121254, "Metastatic malignant melanoma ": 59.45174475157529, "Micturition disorder ": 2.5469118237308632, "Multiple sclerosis ": 4.001563035040417, "Muscle rupture ": 3.566568541899536, "Muscle strain ": 2.1026059651859947, "Musculoskeletal disorder ": 9.391475175348328, "Myocardial infarction ": 5.754736676708825, "Nasal congestion ": 4.3726339451933, "Near death experience ": 3.817954786452341, "Neoplasm malignant ": 7.365277405295108, "Nerve compression ": 7.345848160742834, "Nerve injury ": 4.288157946079251, "Ocular hyperaemia ": 2.5504874357382774, "Ocular vascular disorder ": 28.872690648385948, "Oesophageal disorder ": 7.571547072739969, "Optic atrophy ": 19.319876776397145, "Optic ischaemic neuropathy ": 115.47809232654626, "Optic nerve disorder ": 24.46343675201418, "Optic neuritis ": 3.170918457452134, "Optic neuropathy ": 4.502740865463051, "Orgasm abnormal ": 15.048400772538647, "Overdose ": 2.18976453470984, "Painful erection ": 481.4038272174812, "Panic reaction ": 2.983754783082659, "Papilloedema ": 5.251589461528071, "Paralysis ": 2.0464886766952586, "Paraplegia ": 4.369812844927618, "Parkinson's disease ": 4.699312148714355, "Penile curvature ": 92.49527136490808, "Penile discharge ": 59.62887672071078, "Penile erythema ": 37.17598490690295, "Penile haemorrhage ": 173.79974977648993, "Penile pain ": 423.2955968071438, "Penile swelling ": 74.23997461824624, "Penile vascular disorder ": 260.1887563605293, "Penis disorder ": 207.54539720643365, "Penis injury ": 61.48212710937026, "Peyronie's disease ": 62.175907366819686, "Phimosis ": 12.475380514967512, "Photopsia ": 6.895560408642696, "Pre-existing condition improved ": 16.21813189710212, "Premature ejaculation ": 53.27596748161916, "Prescription drug used without a prescription ": 30.780490277612422, "Priapism ": 134.18168756080345, "Product counterfeit ": 11.3709334368447, "Product dispensing error ": 3.609722227177732, "Product use in unapproved indication ": 2.501008636836417, "Prostate cancer ": 31.883337595859853, "Prostate cancer recurrent ": 21.43258406191056, "Prostatic disorder ": 67.30083479918393, "Prostatic specific antigen increased ": 2.881588671329942, "Prostatomegaly ": 24.74928990905141, "Pruritus genital ": 2.9465436143331285, "Pulmonary hypertension ": 4.155967594779621, "Retinal artery occlusion ": 10.442709032943352, "Retinal artery thrombosis ": 19.101362640800307, "Retinal degeneration ": 15.485430529342086, "Retinal detachment ": 6.72645592197961, "Retinal disorder ": 5.300067416047055, "Retinal haemorrhage ": 8.816283129497826, "Retinal tear ": 12.81989975830042, "Retinal vascular disorder ": 28.04830552645352, "Retinal vascular occlusion ": 9.724317708831189, "Retinal vein occlusion ": 10.096454587330792, "Retinal vein thrombosis ": 11.930644124753902, "Retinitis pigmentosa ": 70.52044323766061, "Road traffic accident ": 9.19918756923096, "Rotator cuff syndrome ": 3.1146242617501745, "Semen volume increased ": 828.1244651341824, "Sexual abuse ": 73.16288561020968, "Sexual dysfunction ": 2.252570829932949, "Sinus congestion ": 2.6223459312784687, "Skin cancer ": 3.5691967828631066, "Skin discolouration ": 2.9061809066167443, "Sleep apnoea syndrome ": 2.697323635516661, "Spinal disorder ": 7.662366685806326, "Spinal fracture ": 4.435105508680346, "Spontaneous penile erection ": 112.22790155085262, "Squamous cell carcinoma ": 2.186302000294299, "Stress ": 2.360335735435324, "Sudden cardiac death ": 2.0580218466295013, "Sudden death ": 5.247155493449808, "Sudden hearing loss ": 10.130752094237904, "Superficial spreading melanoma stage unspecified ": 136.80159954403308, "Suspected counterfeit product ": 39.69444840473262, "Testicular disorder ": 66.94492655886829, "Testicular pain ": 7.936793095010385, "Testicular swelling ": 25.60408404796653, "Therapeutic product effect decreased ": 2.099528820459497, "Therapeutic product effect delayed ": 17.983703138134878, "Therapeutic product effect incomplete ": 3.866545059249072, "Therapeutic product effect prolonged ": 23.9103810965175, "Therapeutic response unexpected ": 4.223510357457662, "Throat cancer ": 13.529051263072487, "Transient global amnesia ": 24.61715033783391, "Transient ischaemic attack ": 2.4243683607311506, "Tunnel vision ": 6.230160285141155, "Type 2 diabetes mellitus ": 3.30274636041995, "Urinary retention ": 2.471502722925835, "Vascular rupture ": 10.729412250067451, "Vein disorder ": 7.525102830157734, "Ventricular fibrillation ": 3.739327185404726, "Vision blurred ": 4.441704833258853, "Visual acuity reduced ": 5.984875990811678, "Visual brightness ": 84.09992242207515, "Visual field defect ": 18.87157777445864, "Visual impairment ": 4.79238179223219, "Vitreous detachment ": 9.086964720024444, "Vitreous floaters ": 4.407535120403818, "Vitreous haemorrhage ": 3.433747060083016, "Weight fluctuation ": 2.527710865504817}
\ No newline at end of file
+{"Achenbach syndrome": 4.101578473109125, "Acute macular neuroretinopathy": 2.7814005030852726, "Administration site hypersensitivity": 4.13625847041923, "Administration site oedema": 2.277301453400202, "Administration site pain": 2.6126580719740096, "Adverse event following immunisation": 4.794937383502068, "Analgesic drug level": 5.109876098179467, "Antibody test": 14.912640545494018, "Aortic embolus": 6.964780810568316, "Application site haematoma": 2.098759434822448, "Application site induration": 2.1186530148071183, "Application site pain": 8.283057857211558, "Application site reaction": 3.855009832658676, "Application site swelling": 4.015728555578475, "Arthralgia": 3.4441512531732554, "Asthenopia": 3.1514848068731496, "Bacille Calmette-Guerin scar reactivation": 2.1488652000772763, "Blood fibrinogen increased": 2.150600888961913, "Blood glucose": 2.6585798010698283, "Blood iron": 8.704212597092177, "Blood pH": 7.211055202161015, "Blood pressure measurement": 4.349012830770303, "Blood pressure normal": 2.374773925719511, "Body temperature": 19.52956912909431, "Body temperature abnormal": 6.432497004454748, "Body temperature fluctuation": 3.336246871383014, "Body temperature increased": 4.496812430317139, "Body temperature normal": 8.378563935560518, "Bone pain": 2.307711177762891, "Cavernous sinus thrombosis": 2.169602818666696, "Cerebral thrombosis": 2.0357723748596954, "Cerebral venous sinus thrombosis": 6.95016248168759, "Cerebral venous thrombosis": 2.771636723059891, "Chest crushing": 2.5179910148902613, "Chills": 6.912602846353084, "Cluster headache": 6.528785624712481, "Cold sweat": 2.1395006553623674, "Cold-stimulus headache": 4.885182367672776, "Computerised tomogram head": 3.9944670922638728, "Contusion": 2.112941484076723, "Coronavirus test": 11.70377963696806, "Delirium febrile": 2.4687283376907296, "Dizziness exertional": 2.521446799598825, "Dizziness postural": 4.491332059504437, "Ear pain": 2.5979098126330453, "Exertional headache": 2.165391210196564, "Eye haematoma": 2.6579099228025327, "Eye pain": 3.405283180857132, "Eyelid contusion": 2.9737956339659952, "Fatigue": 2.877851681821624, "Feeling cold": 5.353143648973064, "Feeling of body temperature change": 3.850049122266809, "Fibrin D dimer": 2.2857593084146357, "Fibrin D dimer increased": 4.443021755136753, "Freezing phenomenon": 4.588452646104823, "Guillain-Barre syndrome": 3.2658442909301035, "Habit cough": 6.333110207060727, "Haemorrhoids thrombosed": 3.332866656597804, "Hangover": 2.82279175504908, "Head discomfort": 2.085345455227328, "Head lag": 2.0638156604354325, "Headache": 4.611332473694857, "Heart rate": 14.527354120125237, "Heparin-induced thrombocytopenia test positive": 5.452241483132324, "Hepatic vein thrombosis": 4.589592230855323, "Hyperhidrosis": 2.4594235711335304, "Hyperpyrexia": 2.0110977485623733, "Immunology test": 2.268006440704129, "Incomplete course of vaccination": 2.6731014549576826, "Influenza": 3.8955790025232697, "Influenza like illness": 7.007662299852867, "Injection": 3.230476365017457, "Injection related reaction": 12.387963556737883, "Injection site deformation": 3.5851390862264005, "Injection site inflammation": 2.415863913260534, "Injection site joint pain": 2.9514671964227617, "Injection site mass": 2.753678409102316, "Injection site pain": 2.6211264514352206, "Injection site reaction": 2.085349500380978, "Injection site warmth": 2.1946293669572845, "Instillation site warmth": 3.679109797020926, "Ischaemic limb pain": 3.632149091269595, "Labyrinthitis": 2.124183589809061, "Lacunar stroke": 2.094601051895581, "Lethargy": 2.106117454528896, "Limb discomfort": 3.1457519871442714, "Limb immobilisation": 2.254119158290001, "Local reaction": 2.527936154737739, "Locomotive syndrome": 4.175009749553353, "Magnetic resonance imaging head": 6.2335499060464965, "Malaise": 2.427841441604324, "Maternal exposure during breast feeding": 6.020379096493335, "Mental fatigue": 3.9641164585000976, "Mesenteric vein thrombosis": 2.151796883319987, "Migraine": 2.7533005778793096, "Migraine with aura": 2.51151248079248, "Miliaria": 2.441887065097841, "Miller Fisher syndrome": 2.2962440539976603, "Motion sickness": 2.014066865782056, "Mouth cyst": 3.012217559750209, "Muscle fatigue": 5.950174438573368, "Myalgia": 4.538089467307391, "Myelitis transverse": 2.404181031213981, "Myocardial strain imaging": 5.046755784132367, "Nausea": 2.301938789363751, "Neck pain": 2.294230055149579, "New daily persistent headache": 3.0585825761844507, "Oral blood blister": 2.7121443729374737, "Oral contusion": 3.003591766876835, "Oversensing": 3.9956211927339895, "Oxygen saturation": 4.276014323009033, "Pain in extremity": 2.87503648627985, "Pain of skin": 3.0271090008913197, "Paroxysmal extreme pain disorder": 2.7964809680412324, "Pelvic haemorrhage": 2.1127590513905026, "Periarthritis": 3.2701739819074604, "Peripheral coldness": 2.963682977807704, "Persistent postural-perceptual dizziness": 3.957372253018416, "Petechiae": 2.331969260360058, "Phlebitis superficial": 2.2106849976023284, "Photophobia": 2.4120326851080343, "Piloerection": 2.3748896071797536, "Portal vein thrombosis": 2.190671791872164, "Portosplenomesenteric venous thrombosis": 4.698057238930264, "Postmenopause": 2.068250237388988, "Pregnancy test": 21.34727233770498, "Primary headache associated with sexual activity": 2.3434763012890563, "Primary stabbing headache": 8.271816248786717, "Procedural dizziness": 4.165006565722893, "Prophylaxis of nausea and vomiting": 7.08133336413608, "Pulmonary pain": 2.7103256645219425, "Puncture site bruise": 5.684479689874633, "Pyrexia": 4.826759878013935, "Q fever": 7.397398860313045, "Renal pain": 2.825816310675893, "Respiratory rate": 2.07891403883624, "Rest regimen": 2.438351307747542, "Retinal migraine": 8.88023104873806, "SARS-CoV-2 antibody test": 4.498789708728403, "SARS-CoV-2 test": 3.09716803473525, "SARS-CoV-2 test negative": 2.760708495761472, "Sensitive skin": 3.106636118846528, "Severe acute respiratory syndrome": 13.639850381456492, "Shoulder injury related to vaccine administration": 3.349168061851437, "Sigmoid sinus thrombosis": 5.732059855188034, "Sinus headache": 7.6617231547048705, "Sinus pain": 4.807433838531261, "Skin sensitisation": 2.469829479942589, "Skin temperature": 12.055694522130567, "Splenic artery thrombosis": 3.828119134697536, "Splenic vein thrombosis": 2.5600212102416813, "Stiff leg syndrome": 2.6034749516263456, "Subacute inflammatory demyelinating polyneuropathy": 4.1143909919312645, "Superficial vein prominence": 2.2391753870412474, "Superficial vein thrombosis": 3.454196932347737, "Superior sagittal sinus thrombosis": 3.275025816556229, "Sweating fever": 14.75842994188447, "Tenderness": 4.349460597378979, "Tension headache": 5.774973266970008, "Thirst": 2.533452971106448, "Thrombophlebitis": 2.5520510126368454, "Thrombosis with thrombocytopenia syndrome": 32.32035859550954, "Thunderclap headache": 3.0823677422193008, "Transverse sinus thrombosis": 3.785041360826914, "Tremor": 2.033667136224111, "Trichodynia": 2.1133194974200094, "Typical aura without headache": 2.259703780435612, "Urine output": 7.722021692636103, "Vaccination failure": 2.1519002182290574, "Vaccination site atrophy": 3.979652304334648, "Vaccination site bruising": 3.810908991854558, "Vaccination site discomfort": 8.16793278801389, "Vaccination site haematoma": 4.335639057343761, "Vaccination site hypersensitivity": 3.970763606307533, "Vaccination site infection": 2.428307199803139, "Vaccination site injury": 2.069528423028377, "Vaccination site joint pain": 2.467958485462502, "Vaccination site mass": 3.2280635335971284, "Vaccination site pain": 2.80636773363106, "Vaccination site reaction": 2.177532215448793, "Vaccination site warmth": 2.0699474567218545, "Varicophlebitis": 4.156817411213976, "Vascular headache": 6.372447584032685, "Vascular pain": 3.212018349578565, "Vasodilatation": 2.463619084568504, "Vertebral artery thrombosis": 2.197257224530865, "Vestibular migraine": 2.083365352413132, "Visceral venous thrombosis": 8.818517865247335, "Vulval haemorrhage": 2.6888684076896694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1147.json
index fc22044c776..6615f31569a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1147.json
@@ -1 +1 @@
-{"Abdominal distension ": 4.147193277436177, "Abdominal pain ": 2.966259794804712, "Abdominal pain upper ": 2.87260161728877, "Abortion induced ": 2.269932421426158, "Acute kidney injury ": 2.6229327439467927, "Adenocarcinoma pancreas ": 46.48740408674061, "Amylase increased ": 16.046099336631087, "Appendicitis ": 2.31312756745515, "Autoimmune hepatitis ": 2.5180574282031314, "Benign neoplasm of thyroid gland ": 39.72980162554838, "Blood glucose abnormal ": 4.417699145759358, "Blood glucose decreased ": 6.525767397011831, "Blood glucose fluctuation ": 3.3877568447712973, "Blood glucose increased ": 8.438156748718939, "Blood potassium decreased ": 2.0288596605025586, "Blood triglycerides increased ": 2.7627493888279755, "Cataract ": 3.3927650197464114, "Cataract operation ": 6.768444630570269, "Cholangiocarcinoma ": 23.73977713867856, "Cholecystectomy ": 6.528368245776929, "Cholecystitis ": 8.163008772306082, "Cholecystitis acute ": 13.510955063997743, "Cholelithiasis ": 17.57159315246899, "Colitis ischaemic ": 3.451765258297684, "Colon cancer ": 2.600259794778375, "Constipation ": 3.4462840761171587, "Coronary artery occlusion ": 2.3532820597172592, "Decreased appetite ": 2.810757746304368, "Dehydration ": 6.978558000224387, "Device failure ": 4.662898401022784, "Device issue ": 3.4452949900252854, "Device leakage ": 3.250891963986737, "Device malfunction ": 4.114687301311931, "Diabetes mellitus inadequate control ": 11.58427270641132, "Diabetic ketoacidosis ": 4.578475012706931, "Diabetic neuropathy ": 3.0294064947212456, "Diabetic retinopathy ": 7.660216272847081, "Diarrhoea ": 3.218254485630264, "Disability ": 5.528267150056457, "Drug dose titration not performed ": 85.72400872359394, "Drug titration error ": 50.32299888265407, "Dyspepsia ": 3.238683133725344, "Eructation ": 19.834821393941635, "Flatulence ": 5.205338735664096, "Follicular thyroid cancer ": 78.31832896643316, "Gallbladder disorder ": 7.830432206339846, "Gastritis ": 3.0652473524924875, "Gastroenteritis ": 3.2234851484166223, "Gastroenteritis viral ": 3.322073186645235, "Gastrointestinal disorder ": 2.3899893909189664, "Gastrointestinal pain ": 2.1806319908026577, "Gastrooesophageal reflux disease ": 2.349150432909007, "Glycosylated haemoglobin abnormal ": 22.177711570348077, "Glycosylated haemoglobin decreased ": 18.19844092307215, "Glycosylated haemoglobin increased ": 11.673120008489402, "Goitre ": 8.501316929733099, "Hepatic cirrhosis ": 2.083593490886563, "Hepatic steatosis ": 3.8951975724747423, "Hiccups ": 4.322369355181453, "Hunger ": 4.773325016414194, "Hyperlipasaemia ": 30.11313092837085, "Hypoglycaemia ": 2.625835609032304, "Hypoglycaemic unconsciousness ": 4.285409504948167, "Ileus ": 2.059842546515042, "Ileus paralytic ": 2.955113419600842, "Impaired gastric emptying ": 20.08028268308285, "Incorrect dose administered by device ": 3.2255219113000813, "Increased appetite ": 2.8510786813976363, "Injection site bruising ": 5.8323701484702735, "Injection site haemorrhage ": 3.296505392407152, "Injection site hypersensitivity ": 9.236246778390662, "Injection site mass ": 3.465013803787788, "Injection site pruritus ": 3.7417049951661103, "Injection site rash ": 12.193248639472198, "Injection site urticaria ": 11.09685250007087, "Intentional dose omission ": 3.1675452057313227, "Intestinal obstruction ": 3.960610521782335, "Knee arthroplasty ": 2.0913548134192794, "Lipase increased ": 24.9459175265347, "Liquid product physical issue ": 4.15020206228933, "Medullary thyroid cancer ": 180.5402773475419, "Metastases to liver ": 2.166453664493657, "Nausea ": 2.8462924962131986, "Neoplasm malignant ": 2.016679449408947, "Nephrolithiasis ": 3.028214169668568, "Obstructive pancreatitis ": 50.02272033820936, "Oedematous pancreatitis ": 28.364171785632944, "Pancreatic carcinoma ": 40.69340676233741, "Pancreatic carcinoma metastatic ": 55.47004813841591, "Pancreatic carcinoma stage IV ": 91.22781600419644, "Pancreatic cyst ": 13.266886028079169, "Pancreatic disorder ": 14.422045817461632, "Pancreatic enzymes increased ": 11.323564113713998, "Pancreatic mass ": 35.71405912352257, "Pancreatic neoplasm ": 51.11664283703716, "Pancreatic pseudocyst ": 25.740166285726552, "Pancreatitis ": 72.59033108836931, "Pancreatitis acute ": 48.316839087891495, "Pancreatitis chronic ": 21.43339116978135, "Pancreatitis necrotising ": 20.419665985565064, "Papillary thyroid cancer ": 79.29530607505393, "Product colour issue ": 6.474242149881435, "Product quality issue ": 3.073033449615231, "Product storage error ": 2.303510269134493, "Retching ": 2.2573875374910592, "Small intestinal obstruction ": 2.7853069617028905, "Surgery ": 2.311258768995714, "Thyroid cancer ": 15.583935307161669, "Thyroid mass ": 26.639622219158987, "Thyroid neoplasm ": 40.03917374379909, "Vomiting ": 4.004113255286001, "Weight decreased ": 4.980125964083531, "Weight loss poor ": 24.623886041282034}
\ No newline at end of file
+{"Acne": 7.180639476509835, "Blood magnesium decreased": 23.500793987521423, "Cerebral infarction": 2.0934559341406835, "Colon cancer": 76.09850701164986, "Colorectal cancer metastatic": 188.6553068742261, "Conjunctivitis": 13.375080194716892, "Decreased appetite": 2.197487095775323, "Dermatitis": 7.49619665145679, "Dermatitis acneiform": 447.14163840948726, "Diarrhoea": 2.5421355000456467, "Disease progression": 10.148890727768045, "Dry skin": 12.709833565517892, "Erythema": 2.259067005610947, "Febrile neutropenia": 3.869850089455552, "Folliculitis": 4.164078951846105, "Gastrointestinal perforation": 16.415169105565433, "Gastrointestinal toxicity": 26.317986804612485, "Haematotoxicity": 20.76880639419742, "Hypocalcaemia": 8.870293595804027, "Hypomagnesaemia": 171.51108215756383, "Infusion related reaction": 3.268563738025764, "Interstitial lung disease": 25.11126217969301, "Leukopenia": 2.431924055444011, "Metastases to liver": 19.326109349843605, "Metastases to lung": 8.126174606056066, "Mucosal inflammation": 9.803165973594096, "Myelosuppression": 2.773139160113045, "Neuropathy peripheral": 20.40595568370156, "Neurotoxicity": 23.748500805987835, "Neutropenia": 5.241400647288639, "Neutrophil count decreased": 10.200712657016911, "Palmar-plantar erythrodysaesthesia syndrome": 3.613964997254565, "Paronychia": 352.93183242823807, "Polyneuropathy": 16.7667016003144, "Pulmonary toxicity": 12.159814541873336, "Rash": 3.281231993156952, "Rash papular": 4.625692974040064, "Rash pustular": 45.27706100547796, "Rectal cancer": 32.906129050448705, "Skin disorder": 32.60552939365841, "Skin exfoliation": 2.359484520363897, "Skin fissures": 47.82367735227727, "Skin lesion": 5.616056866047897, "Skin reaction": 3.559296880273886, "Skin toxicity": 206.6784266870236, "Skin ulcer": 5.445784883195207, "Stomatitis": 17.432560332732237, "Therapy partial responder": 48.86753638740368, "Thrombocytopenia": 3.5219006948755687, "Xerosis": 82.14570575782956}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1148.json
index 5c6e851e329..d35700e240b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1148.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.182743330766667, "Anaemia ": 10.758613656378882, "Dehydration ": 6.42501695655817, "Haemoglobin decreased ": 8.251055182924466}
\ No newline at end of file
+{"Abdominal pain": 4.741973448856593, "Arthritis": 4.097538891715336, "Colitis ulcerative": 30.062009106782423, "Condition aggravated": 3.1888535048955946, "Crohn's disease": 22.84430573938296, "Diarrhoea haemorrhagic": 26.865440061831706, "Frequent bowel movements": 17.89618934955584, "Haematochezia": 9.750225039066098, "Intestinal obstruction": 13.852601989038355, "Off label use": 2.378508714780592, "Pancreatitis": 3.0795259033172697, "Rectal tenesmus": 167.032954129367, "Treatment failure": 5.920606357370708, "Tubulointerstitial nephritis": 12.044150533428796}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1149.json
index 0f6f9afcec5..f52299e305c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1149.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.707435678999812, "Acute myeloid leukaemia ": 84.36671642793335, "Febrile neutropenia ": 22.154718997422755, "Myelosuppression ": 6.565870778276999, "Neutropenia ": 4.324572016306301, "Neutrophil count decreased ": 7.1630388276647485, "Platelet count decreased ": 9.124480373529623, "Pneumonia ": 2.8455797216098664, "Sepsis ": 5.70181607779533, "Subdural haematoma ": 28.560072759698897, "Thrombocytopenia ": 2.1757275131830016, "Tumour lysis syndrome ": 90.17712433636484, "White blood cell count decreased ": 3.5284308059266656}
\ No newline at end of file
+{"Acute kidney injury": 4.12623197585471, "Acute respiratory distress syndrome": 10.85678374776395, "Acute respiratory failure": 6.433474588328673, "Alanine aminotransferase increased": 10.550560580499273, "Aspartate aminotransferase increased": 7.112876397455167, "Blood bilirubin increased": 2.1230529561973968, "Bradycardia": 27.24170596137367, "Bronchopulmonary aspergillosis": 12.393097025086252, "COVID-19": 4.324318823410221, "COVID-19 pneumonia": 79.24514042561715, "COVID-19 treatment": 1777.5010644299607, "Cholestasis": 6.909293019990626, "Death": 7.2890644146422385, "Diffuse alveolar damage": 114.71299213605796, "Disseminated intravascular coagulation": 6.684090588785524, "Drug ineffective": 2.2507060617957, "Drug-induced liver injury": 8.366189115664683, "Electrocardiogram QT prolonged": 2.247743398163608, "Gamma-glutamyltransferase increased": 5.184415482598313, "Genotype drug resistance test positive": 29.351147639113016, "Hepatic cytolysis": 4.606277351717952, "Hepatic enzyme increased": 4.209105204917546, "Hepatic function abnormal": 8.903970992477007, "Hepatitis": 2.9510362980985128, "Hepatocellular injury": 13.326218985502637, "Hepatotoxicity": 5.502463173330285, "Hypertransaminasaemia": 52.94321098013379, "Hypoxia": 5.677856504034782, "Liver disorder": 6.826580337098139, "Liver function test abnormal": 2.8972447562951418, "Liver function test increased": 6.339685724455087, "Maternal exposure during pregnancy": 4.383736214846086, "Mechanical ventilation": 39.63132198673046, "Multiple organ dysfunction syndrome": 7.190293377341101, "Off label use": 2.0107495282669463, "Oxygen saturation decreased": 8.428877165306618, "Pancreatitis acute": 3.7315142581223, "Pneumonia": 2.698978781069119, "Pneumonia aspiration": 18.56393619309545, "Pneumonia bacterial": 25.55400714331598, "Pneumothorax": 6.444235188128433, "Recalled product": 59.47804175195003, "Recalled product administered": 83.13770294081219, "Renal impairment": 10.553466804561412, "Respiratory disorder": 6.422839772711661, "Respiratory failure": 12.782518229360257, "SARS-CoV-2 test positive": 15.945922007038895, "Septic shock": 3.8082340870621, "Sinus bradycardia": 85.0011454386216, "Therapeutic response decreased": 8.76199888577277, "Transaminases increased": 33.74729526364081, "Treatment failure": 4.235880753230681}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/115.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/115.json
index df1a571c137..3209e50c7a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/115.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/115.json
@@ -1 +1 @@
-{"Abdominal pain ": 3.42886689881974, "Anaemia ": 4.566416776386276, "Ankylosing spondylitis ": 32.795236475489894, "Balance disorder ": 2.3809068100988, "Candida infection ": 10.800806483576087, "Colitis ": 7.358622293728293, "Constipation ": 8.10373240605348, "Cytokine release syndrome ": 6.166153471434932, "Cytomegalovirus infection ": 19.074988087482023, "Dehydration ": 3.505046874493984, "Diarrhoea ": 2.467650857473803, "Disease progression ": 15.056807582566115, "Dysphagia ": 2.383374202137721, "Ear pain ": 4.1131135400732886, "Febrile neutropenia ": 2.8218283362710674, "Haemoglobin decreased ": 2.1003973803413603, "Hepatitis ": 6.289550208532255, "Hydronephrosis ": 26.331409446449765, "Hyperthyroidism ": 8.26289013904903, "Hypokalaemia ": 5.313904244089062, "Hypomagnesaemia ": 54.74344519866453, "Hyponatraemia ": 3.300203346687173, "Hypothyroidism ": 5.28004628499475, "Infusion related reaction ": 5.885192582113821, "Intentional product use issue ": 3.18133767053616, "Jaundice ": 2.472686665377009, "Lymphoma transformation ": 1596.3535557185337, "Malignant neoplasm progression ": 4.695144332190645, "Metastases to liver ": 6.005048548619468, "Metastases to lung ": 10.152256653265084, "Mouth ulceration ": 8.224467725938316, "Mucosal inflammation ": 19.538782463051007, "Neoplasm ": 20.45436345506358, "Nervous system disorder ": 9.8152565456443, "Neuropathy peripheral ": 3.1606714961359264, "Neutropenic sepsis ": 42.51883667150901, "Neutrophil count decreased ": 7.131476575282872, "Off label use ": 2.0011936171566296, "Pneumonitis ": 11.961241494089322, "Product use in unapproved indication ": 2.371840889895564, "Productive cough ": 4.641529942280488, "Sepsis ": 3.70301890065032, "Skin candida ": 425.0378573062477, "Skin toxicity ": 34.12375280384661, "Stomatitis ": 2.092740406991724, "Upper respiratory tract infection ": 4.91300134148857, "White blood cell count decreased ": 2.5637776412844078}
\ No newline at end of file
+{"Cardiomyopathy": 32.10236724451382, "Completed suicide": 20.8823279788017, "Constipation": 2.912677411857183, "Drug abuse": 17.210980663496287, "Electrocardiogram QT prolonged": 8.588262012059259, "Hypotension": 3.8469652905045537, "Intentional overdose": 8.797260050481878, "Mental impairment": 26.26973011913314, "Microcytosis": 2486.398161409357, "Neuroleptic malignant syndrome": 19.97782218049421, "Overdose": 6.218184290427175, "Pulmonary oedema": 24.87733847429288, "Sedation": 18.927634474977687, "Somnolence": 2.2024538471768085, "Toxicity to various agents": 24.842176364235915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1150.json
index c56c256a3bd..4eec07df81a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1150.json
@@ -1 +1 @@
-{"Drug interaction ": 12.28502374971411, "Hyperkalaemia ": 37.21698331899839}
\ No newline at end of file
+{"Acute kidney injury": 2.66506377757137, "Altered state of consciousness": 4.04357212866022, "Anaemia": 3.672016155333727, "Bronchitis": 3.928902178751828, "Cardiac failure": 2.960543152402952, "Cardiac failure congestive": 2.477618556748557, "Constipation": 2.5651882661860657, "Deep vein thrombosis": 2.198939800892246, "Dehydration": 2.380800889600213, "Disease progression": 5.665889524991814, "Febrile neutropenia": 5.169660030664931, "Haemoglobin decreased": 2.1962973603249503, "Hypotension": 2.0016634177852004, "Interstitial lung disease": 2.76094355520009, "Neuropathy peripheral": 29.671645069527138, "Neutropenia": 4.66229320943921, "Oedema peripheral": 2.6066241724096844, "Orthostatic hypotension": 7.052992751770212, "Pancytopenia": 7.039671369657623, "Peripheral sensory neuropathy": 29.22554974512547, "Plasma cell myeloma": 42.29686851612029, "Platelet count decreased": 5.960080097788925, "Pneumonia": 3.0151010525220934, "Pneumonitis": 5.55748686591266, "Sepsis": 3.580043646147463, "Septic shock": 4.820167045058219, "Thrombocytopenia": 6.2438623505028925, "Tumour lysis syndrome": 22.633976958755504, "White blood cell count decreased": 2.298869246355656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1151.json
index e7cfb0a2e10..3598f42f639 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1151.json
@@ -1 +1 @@
-{"Condition aggravated ": 2.5670856482066577, "Drug ineffective ": 3.154283395995115, "Drug withdrawal syndrome neonatal ": 41.80210790722083, "Encephalopathy ": 20.375410411569156, "Epilepsy ": 5.661081061762026, "Exposure during pregnancy ": 2.4990749426151813, "Foetal exposure during pregnancy ": 4.969120428596721, "Infantile spasms ": 355.6710013672589, "Magnetic resonance imaging abnormal ": 215.38064940058064, "Magnetic resonance imaging head abnormal ": 1295.492678923104, "Maternal exposure during pregnancy ": 3.5638714753386647, "Neonatal behavioural syndrome ": 2147.1499701144967, "Optic atrophy ": 206.5678709662796, "Optical coherence tomography abnormal ": 3883.8639835737167, "Psychotic disorder ": 8.19166123294794, "Retinal disorder ": 495.6011520809989, "Retinal toxicity ": 363.0742873900012, "Retinogram abnormal ": 2065.285641059615, "Seizure ": 14.97290237231165, "Status epilepticus ": 22.59161791463593, "Therapeutic product effect incomplete ": 2.921944205234387, "Toxicity to various agents ": 6.297140798308555, "Visual acuity reduced ": 16.361061148031908, "Visual field defect ": 386.7798912250898}
\ No newline at end of file
+{"Abdominal pain": 3.4784539042357245, "Acute kidney injury": 7.196393711189057, "Angioedema": 5.602820157227052, "Diarrhoea": 4.189449709798548, "Hyperkalaemia": 4.128842920603967, "Inappropriate schedule of product administration": 2.2003833446325527, "Lactic acidosis": 83.63659740336495, "Lipase increased": 39.6792820680849, "Metabolic acidosis": 14.374027664108525, "Pancreatic carcinoma": 8.513084692751528, "Pancreatitis": 23.734504115941363, "Pancreatitis acute": 39.9984755530353, "Pemphigoid": 20.90526843295087, "Renal failure": 3.589475444829251, "Weight decreased": 2.7928500003767067, "Wrong technique in product usage process": 3.9069895667692784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1152.json
index 251f92e7cf3..8f7799b13ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1152.json
@@ -1 +1 @@
-{"Blister ": 8.470375359176595, "Blood creatine phosphokinase increased ": 5.777031937086752, "Blood glucose increased ": 2.83613018404912, "Blood phosphorus increased ": 65.6311665791848, "Bradycardia ": 2.7250977614074783, "Coma ": 5.755527578245456, "Diabetes mellitus inadequate control ": 17.407003863466525, "Drug interaction ": 3.542857902475625, "Glycosylated haemoglobin increased ": 9.115781457933426, "Hepatic function abnormal ": 2.248476036411119, "Hepatitis ": 7.64271220380885, "Hyperglycaemia ": 3.876675118939951, "Hyperkalaemia ": 3.9967030013145792, "Hypocalcaemia ": 20.615279119395343, "Hypoglycaemia ": 11.471835693692643, "Hypoglycaemic coma ": 17.5055450558708, "Hypomagnesaemia ": 29.407481795694157, "Hypoparathyroidism ": 382.4531151659439, "Intentional overdose ": 4.282044848885023, "Jaundice ": 4.110742156128029, "Lactic acidosis ": 11.333772610235249, "Metabolic acidosis ": 8.964177702938553, "Pancreatitis acute ": 15.667470033671016, "Pemphigoid ": 350.16633668975106, "Renal impairment ": 5.058941146568038, "Rhabdomyolysis ": 3.732917095042711, "Syncope ": 4.616278790280124, "Ventricular tachycardia ": 26.00611653007701}
\ No newline at end of file
+{"Adverse event": 2.1524767072561164, "Arteriovenous fistula operation": 291.3353824941928, "Blood glucose decreased": 2.6863316790540908, "Blood magnesium decreased": 11.610696779373075, "Blood potassium abnormal": 56.25309808655963, "Blood potassium decreased": 20.337569614335195, "Blood potassium increased": 99.879597427072, "Blood pressure abnormal": 3.57282827245338, "Cardiac disorder": 3.0578904527014226, "Cardiac failure congestive": 6.160017305990287, "Cardiac operation": 23.730704008947303, "Cardiac pacemaker insertion": 7.452652347562415, "Cataract operation": 8.733156986795626, "Cellulitis": 2.204686974173617, "Cerebrovascular accident": 2.253545987025229, "Constipation": 11.100229492003235, "Coronavirus infection": 9.024962822027758, "Death": 18.584711376729523, "Dehydration": 3.104804418355805, "Dialysis": 180.3347499129436, "End stage renal disease": 7.336852987913095, "Eye operation": 25.131552688500403, "Faecaloma": 19.02855262070299, "Faeces hard": 26.004480889399872, "Fall": 3.388507421898243, "Flatulence": 7.529590808600435, "Fluid retention": 4.536391466188369, "Gout": 3.912958067469365, "Haematochezia": 2.690360875403733, "Hip fracture": 4.809590408597058, "Hospice care": 109.95741889958036, "Hospitalisation": 62.73956667455344, "Hypercalcaemia": 3.483191689112846, "Hyperkalaemia": 5.957734704570454, "Hypervolaemia": 14.59895076502313, "Hypomagnesaemia": 7.97588770792165, "Ill-defined disorder": 2.848164425155161, "Illness": 2.835803713512031, "Inappropriate schedule of product administration": 6.70791792925514, "Infection": 2.09302967727532, "Intestinal obstruction": 2.419053203659203, "Leg amputation": 19.24300274765625, "Limb injury": 2.5276264457264697, "Localised infection": 11.274868997110266, "Lower limb fracture": 5.364909615279473, "Mental status changes": 2.292959871453379, "Metabolic acidosis": 4.637132775526004, "Myocardial infarction": 2.7420414028758637, "Off label use": 4.022272708323574, "Pericardial effusion": 2.061419099827796, "Pneumonia": 4.029757239127397, "Product colour issue": 27.22284756317718, "Product dose omission in error": 9.88908215681454, "Product dose omission issue": 16.37462033626292, "Product physical issue": 7.1747585753016505, "Product preparation error": 22.44627072962048, "Product solubility abnormal": 26.677681737825765, "Product taste abnormal": 25.202732683878335, "Pulmonary oedema": 4.812157422565927, "Rehabilitation therapy": 45.52358652067237, "Renal disorder": 9.086628365631748, "Renal failure": 2.843566311214428, "Renal impairment": 2.8466656304940057, "Renal transplant": 58.12345243109648, "Spinal operation": 8.799023127062497, "Stent placement": 5.932678121856803, "Surgery": 15.56228087811788, "Thrombosis": 2.3351573519179567, "Toe amputation": 22.579026283911684, "Transfusion": 5.369868749684438, "Treatment noncompliance": 8.344193946134597, "Unevaluable event": 3.6204475883416447, "Urinary tract infection": 4.649251522167996, "Viral infection": 2.1320334894862145}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1153.json
index 51b78694c50..733fb21e69a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1153.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 4.281961212219553, "Abortion induced ": 4.636131950338319, "Accidental exposure to product ": 4.240859210788143, "Affective disorder ": 3.776545546033588, "Aggression ": 7.013525434769154, "Agitation ": 3.1788310313852857, "Agranulocytosis ": 2.426673470568219, "Altered state of consciousness ": 2.4306724795353998, "Amnesia ": 4.040217485068628, "Anger ": 3.642161823997201, "Anticonvulsant drug level increased ": 12.554149828038058, "Apathy ": 2.0269299023052576, "Aphasia ": 2.75008718179607, "Ataxia ": 6.340599246525355, "Atrial fibrillation ": 2.00903114727133, "Atrial flutter ": 3.4506883187713835, "Atrioventricular block ": 17.732712575178837, "Atrioventricular block complete ": 16.681126822021746, "Atrioventricular block first degree ": 9.6620518278023, "Atrioventricular block second degree ": 23.20596074028522, "Aura ": 26.866118462741696, "Balance disorder ": 5.726606707078292, "Behaviour disorder ": 3.726300388674943, "Bipolar disorder ": 3.416398787187151, "Bradycardia ": 6.331013798538694, "Brain neoplasm ": 10.307494621460648, "Brain operation ": 50.2115798337618, "Caesarean section ": 5.660992204909679, "Cardiac pacemaker insertion ": 6.16087547004473, "Change in seizure presentation ": 109.98365812863648, "Cognitive disorder ": 4.782300514816201, "Coordination abnormal ": 6.827824129920297, "Delusion ": 2.5948779157056894, "Depression ": 2.169498110922961, "Developmental delay ": 4.752384742999301, "Diplopia ": 14.679877043416138, "Drop attacks ": 21.328565401013428, "Drug eruption ": 2.218860511221159, "Drug reaction with eosinophilia and systemic symptoms ": 3.873882122695241, "Dysarthria ": 2.353309594413144, "Dyskinesia ": 2.377223616214762, "Dysmorphism ": 6.3371493952647295, "Electrocardiogram PR prolongation ": 51.93661217876928, "Electroencephalogram abnormal ": 9.860301414622144, "Encephalitis ": 2.0739166053675566, "Encephalopathy ": 3.95509993170344, "Epilepsy ": 25.420998187503887, "Fall ": 2.8620276779880887, "Feeling drunk ": 3.626686513189072, "Focal dyscognitive seizures ": 32.42546357454082, "Gait disturbance ": 2.31077461611732, "Generalised tonic-clonic seizure ": 18.054479368923, "Hallucination ": 2.0653796496900183, "Hallucination, auditory ": 3.284362503392343, "Hallucination, visual ": 2.800729348188799, "Head injury ": 5.443299115673567, "Hospitalisation ": 3.5551924961600005, "Inability to afford medication ": 15.869477421325698, "Inappropriate schedule of product administration ": 3.0583068445172046, "Intentional product misuse ": 2.171438806846552, "Irritability ": 4.579458755173473, "Maternal exposure before pregnancy ": 23.43509053558697, "Maternal exposure during breast feeding ": 3.756021888934713, "Maternal exposure during pregnancy ": 6.051934033251827, "Memory impairment ": 3.4185507630444425, "Mental disorder ": 2.702442678953964, "Mood altered ": 2.6923124794718207, "Mood swings ": 2.494658604364797, "Multiple-drug resistance ": 6.261785591153815, "Myoclonic epilepsy ": 17.582460393016248, "Myoclonus ": 6.765741841462612, "No adverse event ": 2.1066351862654185, "Nystagmus ": 7.102562501107253, "Off label use ": 4.113300378642836, "Overdose ": 4.611095916495148, "Paranoia ": 2.999011153345502, "Partial seizures ": 22.32943163219125, "Partial seizures with secondary generalisation ": 47.58366789819265, "Petit mal epilepsy ": 26.92714130644329, "Pneumonia aspiration ": 5.463928137418055, "Pregnancy ": 2.668376815105756, "Prescribed underdose ": 2.582923215234883, "Product administration error ": 2.1304216253860155, "Product availability issue ": 6.260828099343911, "Psychotic disorder ": 5.068324218192024, "Screaming ": 3.666126751812902, "Sedation ": 2.979379989058401, "Seizure ": 16.704293888080826, "Seizure cluster ": 40.73193805559014, "Sinus arrest ": 11.929946652569347, "Sinus bradycardia ": 5.197284563639514, "Sinus node dysfunction ": 31.477807612871057, "Sluggishness ": 4.189586734818063, "Somnolence ": 4.072442606486097, "Staring ": 8.219892698013998, "Status epilepticus ": 22.31444620132796, "Stevens-Johnson syndrome ": 2.080520459582734, "Sudden unexplained death in epilepsy ": 95.01405375128653, "Suicidal ideation ": 5.340918290497152, "Suicide attempt ": 3.241727123380294, "Therapeutic product ineffective ": 11.11257082977158, "Therapeutic response unexpected ": 2.2983915736907807, "Therapy interrupted ": 8.308937075724902, "Treatment noncompliance ": 3.520220791017492, "Underdose ": 3.126602007759616, "Ventricular fibrillation ": 2.128275978840651, "Vertigo ": 3.5528358129278304, "Vision blurred ": 2.6483250451990625, "Wrong technique in product usage process ": 2.2456317062}
\ No newline at end of file
+{"Abdominal distension": 4.0675649462136025, "Alanine aminotransferase increased": 10.911000156161284, "Aspartate aminotransferase increased": 3.2972010100792177, "Cerebral infarction": 7.658873699605869, "Drug ineffective": 6.336807507539418, "Drug resistance": 6.855741903061904, "Dysphagia": 8.147846033925518, "Hepatic cancer": 20.873704873934525, "Hepatic function abnormal": 3.19438945838244, "Hepatitis B": 66.57821702822208, "Hepatitis B DNA assay positive": 1966.8875608376236, "Hepatitis B DNA increased": 801.0197711433434, "Hepatocellular carcinoma": 23.079483594531577, "Jaundice": 4.289553151657469, "Lactic acidosis": 4.63161942658897, "Liver function test increased": 10.802338272128758, "Maternal exposure during pregnancy": 2.955896832124799, "Neoplasm malignant": 4.206086757849832, "Off label use": 2.364648053899156, "Osteoporosis": 2.444969294416385, "Product dispensing error": 16.39437735989556, "Renal impairment": 6.653247428899967, "Suspected counterfeit product": 111.26280859592256, "Transaminases increased": 7.901138314145728, "Treatment noncompliance": 9.15822564032372, "Viral load increased": 72.46452354431024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1154.json
index fc322bf3518..f51e5e75b5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1154.json
@@ -1 +1 @@
-{"Foetal exposure during pregnancy ": 20.004843570465844}
\ No newline at end of file
+{"Actinic keratosis": 103.93834272041644, "Acute kidney injury": 3.710170592924233, "Arthralgia": 2.4287868704359425, "Disease progression": 15.302382951721825, "Electrocardiogram QT prolonged": 10.930756011241996, "General physical health deterioration": 2.1638242702828627, "Hepatotoxicity": 10.494100004576406, "Hyperkeratosis": 100.8274759295399, "Keratoacanthoma": 986.3177331040152, "Keratosis pilaris": 695.27951974193, "Malignant neoplasm progression": 2.600347477976096, "Metastases to central nervous system": 27.65001307014291, "Panniculitis": 79.29499705804155, "Photosensitivity reaction": 36.187932257270695, "Rash": 3.350676068384926, "Rash maculo-papular": 4.550570885456634, "Rash papular": 10.42324674711674, "Skin papilloma": 195.36745689367575, "Skin toxicity": 96.32497356459966, "Squamous cell carcinoma": 148.64567988873424, "Squamous cell carcinoma of skin": 116.26438322960816, "Therapeutic response decreased": 6.2988866555371175, "Toxic epidermal necrolysis": 8.0105525505254, "Uveitis": 21.973604597435383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1155.json
index 46829b444d0..8f8191d07cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1155.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 18.76939921792588, "Alanine aminotransferase increased ": 4.914150141272623, "Ascites ": 6.555868611360491, "Aspartate aminotransferase increased ": 3.878041316451128, "Blood alkaline phosphatase increased ": 3.955033721033424, "Blood bilirubin increased ": 5.303939711692982, "Blood creatine phosphokinase increased ": 2.801894823126513, "Blood lactate dehydrogenase increased ": 4.683304377800899, "Cholestasis ": 4.318429006362471, "Conjunctivitis ": 7.450527180532714, "Drug eruption ": 2.441888774818128, "Drug reaction with eosinophilia and systemic symptoms ": 4.317680861849677, "Drug resistance ": 6.119840934414189, "Eosinophilia ": 7.086952592395356, "Erythema multiforme ": 3.425540464276031, "Foetal exposure during pregnancy ": 2.4677831812204265, "Gamma-glutamyltransferase increased ": 8.272662946028708, "Hepatic cirrhosis ": 6.312214284861156, "Hepatic cytolysis ": 5.169643190242111, "Hepatic enzyme increased ": 5.354667022882833, "Hepatic failure ": 16.531134540057057, "Hepatic necrosis ": 25.42466373157117, "Hepatitis ": 28.122670851311444, "Hepatitis acute ": 9.148280883816811, "Hepatitis cholestatic ": 21.38444524199395, "Hepatitis fulminant ": 33.2294897419774, "Hepatitis toxic ": 18.58154531849236, "Hepatotoxicity ": 17.558247300172678, "Hypersensitivity ": 2.727478208548566, "Jaundice ": 14.291736992269046, "Lactic acidosis ": 3.731626853255287, "Liver function test abnormal ": 16.01907328745246, "Liver function test increased ": 6.119552773167825, "Mouth ulceration ": 5.449754130300336, "Mucosal inflammation ": 3.400807573853644, "Pancreatitis ": 3.915676478387241, "Pregnancy ": 17.038471055472254, "Premature baby ": 2.8678991685492417, "Product residue present ": 44.68375910299325, "Pulmonary oedema ": 2.8204866214109217, "Rash ": 4.934436553749154, "Rash erythematous ": 2.342529101630762, "Rash macular ": 2.817503696732849, "Rash maculo-papular ": 15.258290759774964, "Rash papular ": 3.7476867776574343, "Stevens-Johnson syndrome ": 69.85535057626883, "Toxic epidermal necrolysis ": 21.714389466617284, "Transaminases increased ": 5.905704280481863}
\ No newline at end of file
+{"Acute myeloid leukaemia": 45.275267894327605, "Acute myeloid leukaemia recurrent": 31.57815753876872, "Anaemia": 2.300698703778378, "Autoimmune haemolytic anaemia": 33.438318546870654, "Blood lactate dehydrogenase increased": 5.487730788230329, "Blood phosphorus increased": 19.549374448162773, "Blood test abnormal": 9.50939809993904, "C-reactive protein increased": 2.2423657369786785, "COVID-19": 2.160640567454837, "COVID-19 pneumonia": 10.228899579625168, "Chronic lymphocytic leukaemia": 193.5642667318214, "Chronic lymphocytic leukaemia recurrent": 195.74492636581317, "Cytopenia": 28.754452480772773, "Death": 2.33199452098539, "Drug intolerance": 5.303852887732111, "Febrile neutropenia": 7.490228400116724, "General physical health deterioration": 3.713192362780255, "Hospitalisation": 3.730798558980714, "Hypercalcaemia": 5.942842772370103, "Infection": 6.002955843660029, "Leukopenia": 3.5224926550811446, "Lymphocyte count increased": 29.55071079807676, "Multiple organ dysfunction syndrome": 4.877874921754071, "Neutropenia": 17.096048656974165, "Off label use": 20.46212520373617, "Pancytopenia": 7.634495276913012, "Pneumonia": 2.5018019681893926, "Product use complaint": 49.14598022544505, "Respiratory tract infection": 4.994230510786925, "Richter's syndrome": 427.98059946162687, "Sepsis": 4.401901630177815, "Septic shock": 6.066469106452171, "Splenomegaly": 9.042304972113335, "Thrombocytopenia": 6.670224887387497, "Tumour lysis syndrome": 151.95913557135515, "Unevaluable event": 5.588489032890303, "White blood cell count increased": 4.470140686400225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1156.json
index 5112cb0d506..24f7695488a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1156.json
@@ -1 +1 @@
-{"Acute kidney injury ": 6.391687157265298, "Alanine aminotransferase increased ": 2.1396171183624624, "Amylase increased ": 4.285906087678335, "Anhedonia ": 20.621645383123106, "Ankle fracture ": 8.570846317041044, "Anxiety ": 5.714051501038864, "Azotaemia ": 6.17060581069334, "Blood creatinine abnormal ": 10.09269997643117, "Blood creatinine increased ": 10.32024122744794, "Blood lactic acid increased ": 3.920168711991569, "Blood phosphorus decreased ": 57.434493122318216, "Blood urea increased ": 2.15818720768301, "Bone demineralisation ": 19.189644575770068, "Bone density abnormal ": 8.572696541278924, "Bone density decreased ": 17.818182053264678, "Bone disorder ": 8.314844943384319, "Bone loss ": 15.37925182188718, "Bone pain ": 2.7399374512305257, "CD4 lymphocytes decreased ": 10.5701402684543, "Chronic kidney disease ": 21.521353315105976, "Creatinine renal clearance decreased ": 12.033136367273626, "Decreased activity ": 6.932719736180123, "Drug resistance ": 4.757009853657179, "Economic problem ": 21.96826897371798, "Emotional distress ": 18.20795610370266, "End stage renal disease ": 34.05433917524757, "Fanconi syndrome ": 114.53323562815063, "Fanconi syndrome acquired ": 159.86361809160002, "Femur fracture ": 5.714946019178719, "Foetal death ": 2.3081138750572574, "Foot fracture ": 8.63491394805124, "Fracture ": 11.318158613347029, "Genotype drug resistance test positive ": 18.85327797861016, "Glomerular filtration rate abnormal ": 8.336870075297226, "Glomerular filtration rate decreased ": 7.780712543780693, "Glycosuria ": 46.00087635976696, "Hepatic cancer ": 2.784639777042697, "Hepatic cirrhosis ": 4.001487236745732, "Hepatic failure ": 2.6300231830330025, "Hepatitis B ": 8.142364790830603, "Hepatitis B DNA assay positive ": 254.68624259722085, "Hepatitis B DNA increased ": 150.2480570451599, "Hepatitis B reactivation ": 14.49678923427908, "Hepatocellular carcinoma ": 2.336098690931376, "Hip fracture ": 5.453202905620159, "Hypocalcaemia ": 2.323657612204268, "Hypophosphataemia ": 70.21664773013512, "Hypophosphataemic osteomalacia ": 118.74644814920156, "Immune reconstitution inflammatory syndrome ": 10.533889057586588, "Intervertebral disc degeneration ": 3.236502444989977, "Lactic acidosis ": 5.014528573869841, "Lipase increased ": 3.8011608575206366, "Loss of personal independence in daily activities ": 2.139403117010488, "Lower limb fracture ": 3.7160225128186983, "Metabolic acidosis ": 3.2378047216976333, "Mitochondrial cytopathy ": 34.07459120981709, "Multiple fractures ": 15.613076504346932, "Nephrogenic diabetes insipidus ": 21.26200462109204, "Nephrolithiasis ": 4.13942258032391, "Nephropathy ": 12.039688814163268, "Nephropathy toxic ": 16.632416206986555, "Nephrotic syndrome ": 3.0242179030742102, "Osteoarthritis ": 2.467252235641249, "Osteomalacia ": 68.067425460411, "Osteonecrosis ": 15.360986277732517, "Osteopenia ": 22.847655999828397, "Osteoporosis ": 22.156577081776984, "Pain ": 2.7221747215539653, "Pathological fracture ": 17.89257424991074, "Polydipsia ": 4.57582520644142, "Polyuria ": 3.669147609982113, "Pregnancy ": 4.715708925021231, "Protein total abnormal ": 15.633383854024098, "Proteinuria ": 13.078849431429168, "Quality of life decreased ": 8.559122373653844, "Renal cyst ": 3.4733137808356984, "Renal disorder ": 2.888561970177501, "Renal failure ": 15.05628439390915, "Renal impairment ": 6.310866433041668, "Renal injury ": 16.73859373631145, "Renal transplant ": 11.51444411457478, "Renal tubular acidosis ": 48.93393444774176, "Renal tubular disorder ": 58.145386047958354, "Renal tubular dysfunction ": 178.77414151084986, "Renal tubular necrosis ": 23.450904354446305, "Rib fracture ": 7.506233451525775, "Skeletal injury ": 17.918695881925714, "Spinal compression fracture ": 6.488513385059476, "Spinal fracture ": 3.3640297252950155, "Spinal osteoarthritis ": 4.147915273253359, "Tibia fracture ": 6.192673703728704, "Tooth fracture ": 8.76327400373845, "Tooth loss ": 12.845982061748348, "Treatment noncompliance ": 2.872559235244783, "Tubulointerstitial nephritis ": 6.433778344184137, "Upper limb fracture ": 2.5726813399254023, "Viral load increased ": 62.40505438352553, "Virologic failure ": 8.64454321459482, "Vitamin D deficiency ": 5.256331873717271, "Wrist fracture ": 8.21730543076955}
\ No newline at end of file
+{"Acute myeloid leukaemia": 88.63350198770678, "Acute myeloid leukaemia recurrent": 116.81213716430454, "Agranulocytosis": 3.4474401026453334, "Anaemia": 3.4644083730131223, "Autoimmune haemolytic anaemia": 35.89574560852182, "Blood calcium decreased": 5.576604509235185, "Blood lactate dehydrogenase increased": 7.461897343470305, "Blood phosphorus increased": 35.59914642081516, "Blood potassium increased": 6.749537019165823, "Blood uric acid increased": 5.924699836168286, "Bone marrow failure": 5.440158670275344, "Bone marrow transplant": 54.07719449791175, "COVID-19": 2.1100819943158995, "Chronic lymphocytic leukaemia": 180.23586061947384, "Chronic lymphocytic leukaemia recurrent": 121.38606270607632, "Cytopenia": 62.09923479266813, "Disease progression": 3.74327964526569, "Dysphagia": 2.0152991192318424, "Febrile neutropenia": 26.213232806241308, "Fungal infection": 5.481790008746805, "Haematotoxicity": 30.873930476153586, "Haemoglobin decreased": 3.189824601126929, "Haemolysis": 6.913563576108045, "Haemolytic anaemia": 3.1415786739025995, "Hypercalcaemia": 4.06566124306363, "Immune thrombocytopenia": 2.607625791171775, "Infection": 8.29623509573242, "Intentional product use issue": 2.4442210024458744, "Laboratory test abnormal": 7.153499136707326, "Leukocytosis": 3.435863819164556, "Leukopenia": 3.1889430303002224, "Lymphocyte count decreased": 5.189973608480049, "Mantle cell lymphoma": 81.83991858205871, "Minimal residual disease": 273.2854754181052, "Multiple organ dysfunction syndrome": 2.474981630352914, "Myelodysplastic syndrome": 9.761312109831897, "Myelosuppression": 17.075808294633024, "Neutropenia": 22.12057709051495, "Neutropenic sepsis": 14.671156167849382, "Neutrophil count decreased": 5.673746679770883, "Off label use": 10.22558883199794, "Pancytopenia": 7.896441014530584, "Plasma cell myeloma": 11.670601936418954, "Platelet count decreased": 4.590857825768172, "Pleural effusion": 2.6558107685910435, "Pneumonia": 3.495110506882911, "Pneumonia fungal": 21.67345627342415, "Product use complaint": 20.586116624249826, "Richter's syndrome": 582.5897667451836, "Sepsis": 5.3263170275447465, "Septic shock": 4.587452767872904, "Splenomegaly": 9.377468403728365, "Systemic mycosis": 124.90642388616382, "Thrombocytopenia": 8.09947506212288, "Transplant": 41.37399124678456, "Tumour lysis syndrome": 219.76394475950687, "Unevaluable event": 7.551283964943294, "White blood cell count decreased": 3.4359587230461583, "White blood cell count increased": 3.782038552988482}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1157.json
index 3e502980475..4474d492d6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1157.json
@@ -1 +1 @@
-{"Acute kidney injury ": 9.884150363536811, "Blood creatinine increased ": 13.879377033623626, "Drug ineffective ": 4.015238489153802, "Drug ineffective for unapproved indication ": 517.485225236522, "Neutropenia ": 5.456324683902517, "Off label use ": 8.073773040592714, "Renal failure ": 4.997215000637539}
\ No newline at end of file
+{"Condition aggravated": 40.60543900168347, "Off label use": 11.464922703914748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1158.json
index c46beaff010..64b19d00610 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1158.json
@@ -1 +1 @@
-{"Actinic keratosis ": 83.87006766051883, "Acute hepatic failure ": 2.5856632098605936, "Acute respiratory distress syndrome ": 3.789822796196181, "Adrenal insufficiency ": 2.0674348526239985, "Agitation ": 2.004671025241877, "Alanine aminotransferase increased ": 3.2081831815878634, "Altered state of consciousness ": 2.107890333258095, "Aspartate aminotransferase increased ": 2.587810809898663, "Aspergillus infection ": 57.90992094083037, "Blood alkaline phosphatase increased ": 7.136350447736459, "Blood bilirubin increased ": 2.3244721819495124, "Brain abscess ": 24.318992157061302, "Bronchopulmonary aspergillosis ": 56.17052401359245, "Candida infection ": 9.04924073335292, "Chloropsia ": 127.34994018849072, "Cholestasis ": 9.493769963397629, "Chromatopsia ": 31.27365558416451, "Condition aggravated ": 2.8745137952545097, "Corneal perforation ": 45.04785603545755, "Delirium ": 11.0079677980353, "Dermatitis bullous ": 3.087547490244901, "Dermatitis exfoliative ": 6.540864814234395, "Disease progression ": 3.05463665182331, "Disorganised speech ": 64.52847963130108, "Drug ineffective ": 4.267802979835388, "Drug ineffective for unapproved indication ": 12.449654114990109, "Drug interaction ": 8.643786093496121, "Drug level above therapeutic ": 30.833456662155744, "Drug level below therapeutic ": 104.16445050301728, "Drug level decreased ": 26.564999521990018, "Drug level increased ": 19.49937869865424, "Drug resistance ": 16.994754019021116, "Drug-induced liver injury ": 16.48798107462812, "Dyschromatopsia ": 31.31668213202654, "Dysphoria ": 3.042502860717484, "Electrocardiogram QT prolonged ": 7.561895174704058, "Electrolyte imbalance ": 3.933001171890683, "Encephalopathy ": 3.177670781034009, "Endophthalmitis ": 3.649767260934433, "Eye disorder ": 3.290277163194757, "Fluoride increased ": 921.6795302682484, "Fluorosis ": 1698.8237236018088, "Fungaemia ": 17.673646397854935, "Fungal infection ": 10.191197263319138, "Fusarium infection ": 70.60356992255576, "Gamma-glutamyltransferase increased ": 4.5742565337314405, "Haemoptysis ": 3.313785930625285, "Hallucination ": 22.376448887865354, "Hallucination, auditory ": 12.79315998657443, "Hallucination, visual ": 44.81446573287334, "Hallucinations, mixed ": 14.197228302801186, "Halo vision ": 56.02069897689224, "Hepatic cytolysis ": 5.309468917463771, "Hepatic enzyme increased ": 5.125327474188579, "Hepatic failure ": 2.309191565203176, "Hepatic function abnormal ": 10.931019075800709, "Hepatitis ": 2.4983580605679574, "Hepatitis cholestatic ": 4.952749714864956, "Hepatocellular injury ": 3.2721592095315155, "Hepatotoxicity ": 24.86453081033385, "Hypercalcaemia ": 3.7060830466172767, "Hypertransaminasaemia ": 6.225721462704013, "Hypertrophic osteoarthropathy ": 473.5437946723953, "Hypokalaemia ": 2.495424746309905, "Immunosuppressant drug level increased ": 24.32719721298393, "Initial insomnia ": 5.681869399632131, "Keratitis fungal ": 197.4420336351838, "Liver function test abnormal ": 4.9609106261429785, "Liver function test increased ": 3.532889541110577, "Liver injury ": 14.16604469093819, "Mania ": 2.045216658957756, "Mental disorder ": 8.13225930813876, "Mucormycosis ": 77.5129449144517, "Multiple organ dysfunction syndrome ": 4.690752964401965, "Multiple-drug resistance ": 4.717739569623929, "Musculoskeletal pain ": 2.3127547665720374, "Nephropathy toxic ": 3.982611378022996, "Nervous system disorder ": 5.956735772289727, "Neurotoxicity ": 12.809669691928049, "Off label use ": 2.7950745958642647, "Pathogen resistance ": 20.880268940562104, "Periostitis ": 2483.749219642236, "Photodermatosis ": 135.68739277990338, "Photophobia ": 2.191131781915289, "Photopsia ": 5.974649759405092, "Photosensitivity reaction ": 42.82782057483317, "Pneumonia fungal ": 16.482551629034095, "Polyneuropathy ": 3.3405895687499347, "Posterior reversible encephalopathy syndrome ": 3.1651550451971406, "Procalcitonin increased ": 28.95326954922581, "Product use in unapproved indication ": 2.3142966159196474, "Pseudomonas infection ": 4.730976282542804, "Pseudoporphyria ": 300.1623556152388, "Pulmonary mass ": 4.282430518265219, "Pulmonary mucormycosis ": 127.70810980739692, "Renal impairment ": 2.7864502866202034, "Respiratory failure ": 3.9548621549662863, "Restlessness ": 2.121572359881645, "Rhabdomyolysis ": 2.861615606029979, "Scedosporium infection ": 79.74604688162609, "Septic shock ": 3.4798675389559897, "Skin disorder ": 3.142508081839344, "Skin lesion ": 3.1239454473472112, "Squamous cell carcinoma ": 28.479407296174777, "Squamous cell carcinoma of skin ": 95.47253107069452, "Systemic candida ": 26.521956508645875, "Therapeutic response decreased ": 2.779059586604084, "Therapy non-responder ": 2.206788399979437, "Torsade de pointes ": 8.95837744414638, "Toxic epidermal necrolysis ": 3.840935485416468, "Toxic optic neuropathy ": 98.11416738541432, "Transaminases increased ": 3.703404458461821, "Treatment failure ": 6.608721316496911, "Ventricular extrasystoles ": 2.5093890697269887, "Vision blurred ": 3.728147057338634, "Visual impairment ": 4.336999119729569, "Vitreous floaters ": 4.663987563718454, "Xanthopsia ": 62.95058771245306}
\ No newline at end of file
+{"Abdominal pain": 4.211797262084774, "Constipation": 16.511806005450712, "Diarrhoea": 8.472498228532444}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1159.json
index 82c975b2c85..e5034d43dc5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1159.json
@@ -1 +1 @@
-{"Akathisia ": 18.435545141214945, "Anxiety ": 2.948017995130213, "Completed suicide ": 11.438855501790384, "Condition aggravated ": 4.214090537624172, "Constipation ": 4.492642317966971, "Cough ": 2.38680569926493, "Depression ": 3.577928223883628, "Drug interaction ": 4.033629039292212, "Drug level increased ": 12.777375292865074, "Electrocardiogram QT prolonged ": 6.587641231327645, "General physical health deterioration ": 3.142239720835997, "Hyperhidrosis ": 5.7943674053066045, "Hyponatraemia ": 5.587325299030235, "Insomnia ": 2.0445821955698618, "Irritability ": 17.816496575289133, "Joint swelling ": 3.38548286213186, "Nausea ": 2.431326558267716, "Overdose ": 5.3403495699396695, "Poor quality sleep ": 17.93609851102529, "Product use in unapproved indication ": 2.926132667439656, "Pruritus ": 2.706056077599857, "Serotonin syndrome ": 31.178105101448192, "Sexual dysfunction ": 41.61842060244262, "Sleep disorder ": 4.555933280981491, "Suicidal ideation ": 7.8814558191555, "Toxicity to various agents ": 2.607143829292662, "Tremor ": 2.71015018916042, "Weight increased ": 2.176827815022905}
\ No newline at end of file
+{"Abnormal dreams": 3.37318621636723, "Actinic keratosis": 38.725050026833394, "Acute leukaemia": 6.87834777051642, "Acute lymphocytic leukaemia": 6.079314770104907, "Acute myeloid leukaemia": 18.24100091948522, "Acute myeloid leukaemia recurrent": 5.551240884017208, "Agitation": 2.5421991362655345, "Agranulocytosis": 2.820135410799613, "Alanine aminotransferase increased": 5.240374653879671, "Altered state of consciousness": 5.169284655202852, "Anuria": 2.5166156093434524, "Aspartate aminotransferase increased": 6.447846263701006, "Aspergilloma": 54.06000265178909, "Aspergillus infection": 38.75906954946362, "Bacteraemia": 2.203077559365195, "Bacterial infection": 2.1349486394030004, "Bacterial sepsis": 3.953155004341159, "Bilirubin conjugated increased": 7.218602277848142, "Blindness": 2.007358988849574, "Blindness transient": 2.4104147160362044, "Blood albumin decreased": 4.080946502366965, "Blood alkaline phosphatase increased": 10.306379197647791, "Blood beta-D-glucan increased": 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"Visual acuity reduced": 5.0568752964547246, "Visual brightness": 37.90209187304908, "Visual field defect": 4.902048195383463, "Visual impairment": 8.021913558434237, "Vitreous floaters": 2.7677161556824275, "Xanthopsia": 271.5953308578652}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/116.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/116.json
index c4dbd2e3ef9..9cb72334e66 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/116.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/116.json
@@ -1 +1 @@
-{"Acute pulmonary oedema ": 60.59716447575847, "Anaemia neonatal ": 364.09945230536647, "Bronchopulmonary dysplasia ": 287.70864136046146, "Congenital arterial malformation ": 1355.953495327631, "Delivery ": 3975.062946982816, "Exposure during pregnancy ": 12.760720574698691, "Foetal exposure during pregnancy ": 50.82404342107393, "Foetal growth abnormality ": 2117.559489195261, "Hyperbilirubinaemia ": 11.585104554602909, "Low birth weight baby ": 51.716120868502806, "Maternal exposure during pregnancy ": 68.47129950844143, "Neonatal hypocalcaemia ": 1996.5794647630812, "Neonatal respiratory distress syndrome ": 108.29782339958244, "Normal labour ": 168024.3977411458, "Oxygen saturation decreased ": 4.237081668099353, "Premature baby ": 146.91602308270248, "Premature delivery ": 631.9486856443345, "Premature rupture of membranes ": 124.85658155349412, "Product use in unapproved indication ": 27.212735058239723, "Pulmonary oedema ": 4.59165045405609, "Respiratory distress ": 9.197036250336888, "Stillbirth ": 98.94594387338395, "Superficial vein thrombosis ": 41.86480049884824, "Tachypnoea ": 15.340977595832918}
\ No newline at end of file
+{"Abdominal tenderness": 5.133888882265375, "Abscess bacterial": 430.01279390507, "Abscess fungal": 181.2853996352168, "Activated partial thromboplastin time prolonged": 3.2819947731632566, "Acute graft versus host disease in skin": 5.158804254737412, "Acute lymphocytic leukaemia": 42.91349536039485, "Acute lymphocytic leukaemia recurrent": 75.60729679708479, "Acute myeloid leukaemia": 6.873000715560991, "Acute respiratory distress syndrome": 2.955839166215123, "Adenovirus infection": 9.183100393507374, "Alanine aminotransferase increased": 2.427576404015586, "Altered state of consciousness": 2.185810600706365, "Ammonia increased": 4.166168267425813, "Amylase increased": 15.8399167838061, "Anal stenosis": 241.2498489251392, "Anaphylactoid reaction": 2.073248773058864, "Angiocentric lymphoma": 319.67728143141954, "Antithrombin III decreased": 121.48788414995752, "Aplastic anaemia": 10.132184254094309, "Ascites": 2.9117593433638747, "Aspartate aminotransferase increased": 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"Hyperlipidaemia": 6.827131841990698, "Hyperplasia": 43.44421060422945, "Hypersensitivity": 2.0417621182635104, "Hypertransaminasaemia": 5.421282670953528, "Hypertriglyceridaemia": 39.53357680926413, "Hypoalbuminaemia": 6.487132446655406, "Hypofibrinogenaemia": 23.917903852160908, "Hypophagia": 3.478961303036884, "Hyporeflexia": 7.198618205930351, "Ileus": 4.122709627905447, "Ileus paralytic": 9.51751603334407, "Immune reconstitution inflammatory syndrome": 2.080511778153732, "Inappropriate antidiuretic hormone secretion": 8.68460498726035, "Inguinal hernia": 11.00472420069494, "Intracranial pressure increased": 6.028169170140573, "Jaundice": 2.2099360541617314, "Jaundice cholestatic": 3.580166422718817, "Kidney duplex": 287.64491534754814, "Klebsiella infection": 7.15072821700264, "Klebsiella sepsis": 42.801394379308704, "Lennox-Gastaut syndrome": 252.46334778932453, "Leptotrichia infection": 629.9935959036418, "Leukaemia": 3.2715742746403347, "Leukaemia recurrent": 39.38746816765458, 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2.80990899806932, "Pneumonia fungal": 17.05388200448535, "Posterior reversible encephalopathy syndrome": 60.56914711338992, "Posture abnormal": 17.641828859563073, "Prothrombin time prolonged": 2.426664609599449, "Pseudomonal sepsis": 319.775220112462, "Pseudomonas infection": 12.415466277968063, "Pulmonary haemorrhage": 6.85738638256523, "Pulmonary valve stenosis": 40.59039606917415, "Pulse absent": 3.5508766527768394, "Pyelocaliectasis": 62.71274736489988, "Pyomyositis": 56.19290957740202, "Renal mass": 11.9801263927708, "Renal tubular necrosis": 2.8616712700174745, "Rhinorrhoea": 2.687526536131911, "Rhinovirus infection": 102.53648638889446, "Scrotal infection": 136.08489480916026, "Scrotal oedema": 22.04026547274284, "Second primary malignancy": 11.1642737739218, "Secondary immunodeficiency": 776.0485639878335, "Seizure": 2.0388454041885047, "Sepsis": 6.1798630716004, "Septic shock": 9.60473461836865, "Sinusitis fungal": 34.31395774472666, "Staphylococcal bacteraemia": 16.095596665461926, "Staphylococcal infection": 6.086755783066449, "Stenotrophomonas infection": 18.551315214788676, "Steroid diabetes": 12.635004786601137, "Stomatitis": 3.141583824361632, "Superior sagittal sinus thrombosis": 110.17746461657556, "Systemic candida": 9.784858006065411, "Systemic mycosis": 18.281829632326176, "T-cell type acute leukaemia": 96.109955574952, "Tachypnoea": 2.8736869254137347, "Temporal lobe epilepsy": 137.07824227255696, "Thymus hypoplasia": 2467.4379959956373, "Tooth hypoplasia": 110.99681463570089, "Transverse sinus thrombosis": 29.499874221664477, "Tumour lysis syndrome": 10.972282079807687, "Type 1 diabetes mellitus": 2.793739560365604, "Venoocclusive disease": 11.276923933617104, "Venoocclusive liver disease": 59.22517512303188, "Venous thrombosis": 17.490025553375926, "Venous thrombosis limb": 3.6051049870984873, "Viraemia": 119.14962675355363, "Viral haemorrhagic cystitis": 20.089670572403808, "Viral infection": 27.161805730258617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1160.json
index 02464170e62..ded90c0fb61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1160.json
@@ -1 +1 @@
-{"Adverse drug reaction ": 4.670840317891651, "Adverse event ": 2.106565205965936, "Ageusia ": 2.773918290459512, "Alanine aminotransferase increased ": 4.2779773441792575, "Amylase increased ": 3.026984729139077, "Angiosarcoma ": 41.77293056198687, "Angiosarcoma metastatic ": 172.01202449436644, "Aspartate aminotransferase increased ": 4.301487648370355, "Azotaemia ": 2.1059066794008943, "Biliary obstruction ": 4.3957767488551465, "Blood albumin decreased ": 2.402585991408558, "Blood alkaline phosphatase increased ": 2.570788700297784, "Blood bilirubin increased ": 7.609380045347937, "Blood creatinine abnormal ": 2.4498793095629003, "Blood pressure increased ": 3.3709184457055352, "Blood sodium decreased ": 2.5845965020242723, "Blood thyroid stimulating hormone increased ": 8.970993236378499, "Blood urine present ": 3.691495286575616, "Bone cancer ": 8.150892251551506, "Bone neoplasm ": 12.676781439013318, "Brain neoplasm ": 6.669036259736003, "Brain neoplasm malignant ": 3.735062733615496, "Cancer pain ": 3.3998452964372072, "Cardiac dysfunction ": 3.0123516808971083, "Cardiac failure ": 2.5651345852774097, "Cardiac failure acute ": 2.144540732028472, "Cardiotoxicity ": 6.360747088098486, "Cataract operation ": 3.102775735170774, "Cell death ": 3.2183904173091102, "Cholecystectomy ": 2.0929049844502297, "Clear cell renal cell carcinoma ": 28.76355627670105, "Death ": 11.220792342365764, "Decreased appetite ": 3.903263948456488, "Dehydration ": 2.7440184002632497, "Dialysis ": 2.6534595252971527, "Diarrhoea ": 3.738781885370754, "Disease progression ": 8.687893699150628, "Dry skin ": 2.319082014165, "Dry throat ": 2.1581839540940706, "Dysgeusia ": 2.4895757228936373, "Eating disorder ": 2.503788838840824, "Ejection fraction decreased ": 9.94933144988663, "Electrolyte imbalance ": 2.1646289537605106, "Emergency care examination ": 16.49954482242419, "Endometrial stromal sarcoma ": 134.39772500777065, "Eyelash discolouration ": 56.772157237581325, 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\ No newline at end of file
+{"Accident": 9.273741952947256, "Accident at work": 26.149745521403563, "Accidental exposure to product by child": 4.213169256520356, "Acquired immunodeficiency syndrome": 11.27570503361228, "Actinic keratosis": 5.148200600517941, "Acute myocardial infarction": 3.071445946813132, "Alcohol interaction": 5.777872679256765, "Amnesia": 2.182108693692677, "Aneurysm": 6.2984258876672055, "Angina pectoris": 2.8959427574340846, "Angiopathy": 5.424495460314242, "Ankle fracture": 2.8047186156148074, "Anorgasmia": 26.84877206451416, "Aortic aneurysm": 3.35385269780366, "Arterial occlusive disease": 6.504272692991568, "Arthropathy": 2.790431530259921, "Asthenopia": 3.332223315647417, "Back disorder": 16.732121240186682, "Back injury": 5.270025736972341, "Basal cell carcinoma": 2.3212879676148157, "Benign prostatic hyperplasia": 8.661753688545563, "Bipolar disorder": 2.4014734358127616, "Blindness": 13.731050790795852, "Blindness transient": 7.056607911421479, "Blindness unilateral": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1161.json
index a8df358352d..5dbc47e4439 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1161.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 24.820892408198187, "Acute pulmonary oedema ": 42.04640313285206, "Bone marrow failure ": 72.6453326643622, "Cardiac failure ": 3.779580657587427, "Cellulitis ": 9.518420207280547, "Congenital aplasia ": 130.31133910646474, "Cytopenia ": 33.687354447347786, "Disease progression ": 4.415020525486679, "Ejection fraction decreased ": 28.066634161035328, "Febrile neutropenia ": 55.21249773350638, "Infection ": 3.754817677984384, "Neutropenia ": 8.102598659223833, "Neutropenic sepsis ": 138.48004694764285, "Pancytopenia ": 7.139146307915707, "Pneumonia ": 3.997308280556528, "Pneumonia fungal ": 91.18708181728309, "Rash ": 2.7462604746952293, "Rash maculo-papular ": 10.775519792920134, "Sepsis ": 14.025509133946256, "Septic shock ": 10.34632368369127, "Thrombocytopenia ": 5.532761549092627}
\ No newline at end of file
+{"Abdominal distension": 4.147023497536793, "Abdominal pain": 2.966138326258262, "Abdominal pain upper": 2.8724840011447514, "Abortion induced": 2.269839524617488, "Acute kidney injury": 2.6228253495509035, "Adenocarcinoma pancreas": 46.48550131753616, "Amylase increased": 16.045442514892073, "Appendicitis": 2.313032901340093, "Autoimmune hepatitis": 2.5179543769007697, "Benign neoplasm of thyroid gland": 39.728175712834606, "Blood glucose abnormal": 4.417518330553008, "Blood glucose decreased": 6.525500249064569, "Blood glucose fluctuation": 3.3876181909661365, "Blood glucose increased": 8.43781114323918, "Blood potassium decreased": 2.0287766255000714, "Blood triglycerides increased": 2.762636318469485, "Cataract": 3.3926261458996727, "Cataract operation": 6.768167624028753, "Cholangiocarcinoma": 23.73880556253168, "Cholecystectomy": 6.528101061006101, "Cholecystitis": 8.162674666006826, "Cholecystitis acute": 13.510402089673386, "Cholelithiasis": 17.570873763067, "Colitis ischaemic": 3.451623993523025, "Colon cancer": 2.6001533765456406, "Constipation": 3.446142975531651, "Coronary artery occlusion": 2.3531857502563147, "Decreased appetite": 2.810615314216759, "Dehydration": 6.977897230796916, "Device failure": 4.662707564629159, "Device issue": 3.4451539829503046, "Device leakage": 3.250758922284854, "Device malfunction": 4.114518891571745, "Diabetes mellitus inadequate control": 11.583798439941091, "Diabetic ketoacidosis": 4.578287595840591, "Diabetic neuropathy": 3.0292825180028204, "Diabetic retinopathy": 7.659902766667088, "Diarrhoea": 3.2180957060822117, "Disability": 5.528040881811376, "Drug dose titration not performed": 85.72050024650936, "Drug titration error": 50.32093933856398, "Dyspepsia": 3.2385505533081664, "Eructation": 19.834009462607053, "Flatulence": 5.204700462311612, "Follicular thyroid cancer": 78.31512385967058, "Gallbladder disorder": 7.830111722130526, "Gastritis": 3.0651218956111297, "Gastroenteritis": 3.223353219444585, "Gastroenteritis viral": 3.3219372295646106, "Gastrointestinal disorder": 2.389816140827804, "Gastrointestinal pain": 2.1805427462526974, "Gastrooesophageal reflux disease": 2.349054276400228, "Glycosylated haemoglobin abnormal": 22.176803919062717, "Glycosylated haemoglobin decreased": 18.197696159033992, "Glycosylated haemoglobin increased": 11.67264215075313, "Goitre": 8.500968997216617, "Hepatic cirrhosis": 2.08350821616508, "Hepatic steatosis": 3.895038146208304, "Hiccups": 4.3221924562634975, "Hunger": 4.773129661526392, "Hyperlipasaemia": 30.111898522614144, "Hypoglycaemia": 2.625639252258717, "Hypoglycaemic unconsciousness": 4.285234116336723, "Ileus": 2.059758247138987, "Ileus paralytic": 2.9549924825360705, "Impaired gastric emptying": 20.079460769484044, "Incorrect dose administered by device": 3.225389907080324, "Increased appetite": 2.8509619965252115, "Injection site bruising": 5.832131430485554, "Injection site haemorrhage": 3.2963704754508103, "Injection site hypersensitivity": 9.235868772515715, "Injection site mass": 3.4648719920413877, "Injection site pruritus": 3.7415518322522336, "Injection site rash": 12.192749550978744, "Injection site urticaria": 11.096398319837252, "Intentional dose omission": 3.1674155742026047, "Intestinal obstruction": 3.9604484171539744, "Knee arthroplasty": 2.091269222626312, "Lipase increased": 24.944896290529577, "Liquid product physical issue": 4.150032216630228, "Medullary thyroid cancer": 180.5328882566851, "Metastases to liver": 2.1663649974519754, "Nausea": 2.8461628332600624, "Neoplasm malignant": 2.0165969064812894, "Nephrolithiasis": 3.0275882904565345, "Obstructive pancreatitis": 50.02067307472699, "Oedematous pancreatitis": 28.363010968782906, "Pancreatic carcinoma": 40.6917403216226, "Pancreatic carcinoma metastatic": 55.46777742420722, "Pancreatic carcinoma stage IV": 91.22408240378684, "Pancreatic cyst": 13.266343079431127, "Pancreatic disorder": 14.42145555647259, "Pancreatic enzymes increased": 11.32310069560502, "Pancreatic mass": 35.71259746322911, "Pancreatic neoplasm": 51.11455077783836, "Pancreatic pseudocyst": 25.739112851880428, "Pancreatitis": 72.58735547911554, "Pancreatitis acute": 48.31485992133669, "Pancreatitis chronic": 21.432513941725308, "Pancreatitis necrotising": 20.418830244227827, "Papillary thyroid cancer": 79.29206029468016, "Product colour issue": 6.473977193714279, "Product quality issue": 3.0729076703986844, "Product storage error": 2.3034159927414906, "Retching": 2.2572951491565862, "Small intestinal obstruction": 2.7851929746143083, "Surgery": 2.311164174720255, "Thyroid cancer": 15.583297443412546, "Thyroid mass": 26.638531864095597, "Thyroid neoplasm": 40.037535085646354, "Vomiting": 4.003894986364196, "Weight decreased": 4.979922020569272, "Weight loss poor": 24.622878240214277}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1162.json
index faab959c3c7..7f26ba2a97b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1162.json
@@ -1 +1 @@
-{"Aggression ": 8.930435894476338, "Anxiety ": 3.897745817976608, "Depression ": 3.248671775367829, "Drug interaction ": 3.393281379710399, "Insomnia ": 5.2608246701273504, "Irritability ": 8.507842657057793, "Nightmare ": 13.11133970060878, "Off label use ": 2.919365000850682, "Suicidal ideation ": 7.910600710596054, "Weight increased ": 3.1680145728063605}
\ No newline at end of file
+{"Abdominal pain": 2.182743330766667, "Anaemia": 10.758613656378882, "Dehydration": 6.424674052396681, "Haemoglobin decreased": 8.251055182924466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1163.json
index b2edb504011..78a92a3b976 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1163.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 5.693584396010497, "Aspartate aminotransferase increased ": 5.088305198231373, "Blood albumin decreased ": 6.441289094879018, "Blood alkaline phosphatase increased ": 2.523291377501947, "Blood bilirubin increased ": 2.1730741132294216, "Blood potassium increased ": 2.00065086666733, "Bradycardia ": 7.817601448485394, "Cardiac failure ": 2.795446350918977, "Constipation ": 4.290930352864862, "Death ": 7.98864785379812, "Decreased appetite ": 2.2346498787395888, "Disease progression ": 29.897350381351128, "Drug-induced liver injury ": 2.759747176665323, "Dysgeusia ": 3.847660958208119, "Dyspepsia ": 2.206614579092871, "Dysphagia ": 2.721957920702261, "Eating disorder ": 2.673495988593454, "Electrocardiogram QT prolonged ": 7.204074579501508, "Feeding disorder ": 3.2814206874155505, "Fluid retention ": 2.656702451330084, "Gastrooesophageal reflux disease ": 2.146538766138853, "Generalised oedema ": 4.499413095760138, "Haemoptysis ": 2.580986328000739, "Heart rate decreased ": 3.912367495704781, "Hepatic enzyme increased ": 3.6045794617790343, "Hepatic failure ": 3.4069040832345747, "Hepatic function abnormal ": 5.255674747529746, "Hepatitis ": 2.1524371245495257, "Hepatotoxicity ": 10.712764797639675, "Hypertransaminasaemia ": 5.77310332854318, "Interstitial lung disease ": 5.420917694929534, "Liver disorder ": 2.6982119486132814, "Liver function test abnormal ": 2.4478917049008104, "Liver function test increased ": 6.77451798307465, "Liver injury ": 2.6201608926682707, "Lung adenocarcinoma ": 44.00791185422814, "Lung adenocarcinoma stage IV ": 85.52356478007565, "Lung cancer metastatic ": 23.50581052782383, "Lung neoplasm malignant ": 65.06347904480481, "Neoplasm malignant ": 6.995653352001748, "Neoplasm progression ": 55.10796811966359, "Neutropenia ": 2.0999137440753293, "Non-small cell lung cancer ": 94.28499747426464, "Non-small cell lung cancer metastatic ": 149.7730456624511, "Odynophagia ": 3.7569855983701848, "Oedema ": 6.1516870180396825, "Oedema peripheral ": 7.280379713610663, "Oesophageal candidiasis ": 6.359841939999329, "Oesophageal pain ": 8.37860289029666, "Oesophageal ulcer ": 39.54303907059105, "Oesophagitis ": 16.014376240973323, "Pericardial effusion ": 6.813298819426448, "Peripheral swelling ": 2.2426008614593327, "Photopsia ": 29.1764804164103, "Pleural effusion ": 8.049614158492712, "Pneumonia ": 4.06922730623706, "Pneumonitis ": 11.01864522069129, "Product use in unapproved indication ": 4.037267308891923, "Protein total decreased ": 9.520158694719164, "Pulmonary embolism ": 3.251779859054128, "Pulmonary oedema ": 4.487951841546872, "Pulmonary thrombosis ": 4.601415207929729, "Renal abscess ": 63.46430004001686, "Renal cyst ": 16.689673689554763, "Renal impairment ": 3.20733883051391, "Respiratory failure ": 4.1900475124607, "Second primary malignancy ": 10.644337466105158, "Sinus bradycardia ": 7.728385090754297, "Taste disorder ": 6.141023578679089, "Thrombosis ": 2.7876026998942804, "Transaminases increased ": 4.761687797820829, "Vasogenic cerebral oedema ": 64.93326519523193, "Visual impairment ": 5.382014105059722, "Vitreous floaters ": 6.663853560790042, "Vomiting ": 2.2027100398522705}
\ No newline at end of file
+{"Acute kidney injury": 2.707435678999812, "Acute myeloid leukaemia": 84.36671642793335, "Febrile neutropenia": 22.154718997422755, "Myelosuppression": 6.565870778276999, "Neutropenia": 4.324386056392034, "Neutrophil count decreased": 7.1630388276647485, "Platelet count decreased": 9.124480373529623, "Pneumonia": 2.8455797216098664, "Sepsis": 5.70181607779533, "Subdural haematoma": 28.560072759698897, "Thrombocytopenia": 2.175522863390871, "Tumour lysis syndrome": 90.17712433636484, "White blood cell count decreased": 3.5284308059266656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1164.json
index ebfec1372d2..1bfa8cec18f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1164.json
@@ -1 +1 @@
-{"Abdominal wall haematoma ": 19.39152434148882, "Abnormal loss of weight ": 8.345556497234348, "Abnormal uterine bleeding ": 61.50583073755554, "Activated partial thromboplastin time prolonged ": 12.21657314395192, "Acute kidney injury ": 5.271679558945085, "Acute respiratory failure ": 3.711039483353092, "Anaemia ": 2.545106159491493, "Anticoagulation drug level above therapeutic ": 13.327564404483804, "Atrial fibrillation ": 4.146959022064968, "Blood loss anaemia ": 39.12333146256927, "Blood urine present ": 12.087292543389566, "Cardiac failure congestive ": 2.1761115184572914, "Cerebellar haemorrhage ": 10.04960361465968, "Cerebral haematoma ": 13.490481591423986, "Cerebral haemorrhage ": 10.43877444302644, "Cerebral infarction ": 2.1204028019335257, "Cerebral thrombosis ": 8.356462959123247, "Cholestasis ": 2.386691429780636, "Chronic obstructive pulmonary disease ": 2.593022001589105, "Coagulopathy ": 13.740802257186036, "Contusion ": 2.970303125603756, "Deep vein thrombosis ": 7.124183162691977, "Dermatitis bullous ": 2.135694196566929, "Diarrhoea haemorrhagic ": 2.3036907577629604, "Diverticulum intestinal haemorrhagic ": 52.14436765853645, "Drug interaction ": 6.378505066288155, "Duodenal ulcer haemorrhage ": 14.474002180915386, "Ear haemorrhage ": 12.908940136082927, "Ecchymosis ": 4.354286915935052, "Embolic stroke ": 9.72745224184898, "Emphysema ": 2.5593348205418978, "Epistaxis ": 10.310139729868803, "Eye haemorrhage ": 2.640729038651833, "Faeces discoloured ": 2.1264585238691427, "Fall ": 2.2359257654830818, "Gastric haemorrhage ": 3.496552743041361, "Gastric ulcer ": 5.430387260288251, "Gastric ulcer haemorrhage ": 17.499262302920044, "Gastritis haemorrhagic ": 11.77387208209341, "Gastrointestinal haemorrhage ": 35.33280087468717, "Gastrointestinal polyp haemorrhage ": 50.88177702095466, "Gastrointestinal vascular malformation haemorrhagic ": 113.62537844237836, "Gingival bleeding ": 13.3193976871396, "Haemarthrosis ": 13.211687972133172, "Haematemesis ": 7.784884223034125, "Haematochezia ": 4.947048110993616, "Haematoma ": 9.002013364122046, "Haematoma muscle ": 16.142705403003053, "Haematuria ": 19.47667888848008, "Haemoglobin decreased ": 3.1925131517531797, "Haemoptysis ": 11.070736938417404, "Haemorrhage ": 8.218444847100072, "Haemorrhage intracranial ": 10.166937592885102, "Haemorrhage subcutaneous ": 5.863796995998415, "Haemorrhage urinary tract ": 7.389123279562001, "Haemorrhagic arteriovenous malformation ": 245.64703109920376, "Haemorrhagic diathesis ": 8.985751905708424, "Haemorrhagic stroke ": 23.98177836364397, "Haemorrhagic transformation stroke ": 31.698128636877968, "Haemorrhoidal haemorrhage ": 45.96255273256549, "Haemothorax ": 20.66909927323392, "Hemiplegia ": 6.492058862692474, "Hepatitis cholestatic ": 2.341395234823331, "Hypervolaemia ": 3.858669192579097, "Hypovolaemic shock ": 18.02064426702114, "Incorrect dose administered ": 2.4655129228295745, "Increased tendency to bruise ": 9.307048360865997, "Internal haemorrhage ": 91.2080853710169, "International normalised ratio increased ": 9.560471500323258, "Intestinal haemorrhage ": 4.10846404499321, "Intra-abdominal haematoma ": 7.838536786592517, "Iron deficiency anaemia ": 8.015215115181691, "Ischaemic stroke ": 8.512942910284098, "Labelled drug-drug interaction medication error ": 11.869543284749875, "Lactic acidosis ": 2.555879522454513, "Large intestinal haemorrhage ": 15.773913364199675, "Lower gastrointestinal haemorrhage ": 65.06573702400466, "Melaena ": 9.831445625659468, "Mouth haemorrhage ": 10.192896405835326, "Muscle haemorrhage ": 9.088419294248208, "Occult blood positive ": 9.944278996874278, "Pemphigoid ": 2.415875461209798, "Peptic ulcer haemorrhage ": 20.91946217650754, "Pericardial haemorrhage ": 24.289482190610336, "Peripheral artery occlusion ": 11.790499690839017, "Post procedural haemorrhage ": 15.694598329229065, "Prescribed underdose ": 4.39168114912845, "Procedural haemorrhage ": 17.40844868134598, "Product prescribing issue ": 5.062092678220416, "Prothrombin time prolonged ": 12.939366073535084, "Pulmonary alveolar haemorrhage ": 9.978223399768538, "Pulmonary embolism ": 4.876961422887843, "Pulmonary haemorrhage ": 8.910864175538967, "Pulmonary thrombosis ": 5.562793845876686, "Purpura ": 3.444562522533756, "Rectal haemorrhage ": 19.42164022474268, "Renal haemorrhage ": 49.003750226858166, "Respiratory failure ": 2.8781412408089047, "Retroperitoneal haematoma ": 10.66453769730496, "Retroperitoneal haemorrhage ": 13.873805144048994, "Right ventricular failure ": 3.661995248119708, "Shock haemorrhagic ": 20.1780348326518, "Sinus bradycardia ": 2.7091539301764347, "Skin haemorrhage ": 8.552661202606576, "Subarachnoid haemorrhage ": 8.105009312477103, "Subcutaneous haematoma ": 12.316947880461283, "Subdural haematoma ": 12.921724845679815, "Subdural haemorrhage ": 8.478360325915741, "Thalamus haemorrhage ": 12.366845981219775, "Thrombosis ": 3.617483521030592, "Treatment noncompliance ": 2.304010127136201, "Ulcer haemorrhage ": 3.3207938069000185, "Upper gastrointestinal haemorrhage ": 38.24743968432063, "Uterine haemorrhage ": 11.54904791316683, "Vaginal haemorrhage ": 8.649417851682612, "Wound haemorrhage ": 13.521369733008749}
\ No newline at end of file
+{"Drug interaction": 12.28502374971411, "Hyperkalaemia": 37.211852010524645}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1165.json
index e1cd20d5d3c..a9a0d0c9f14 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1165.json
@@ -1 +1 @@
-{"Acute kidney injury ": 20.09568862652269, "Anuria ": 95.8692694470784, "Hyperkalaemia ": 23.125419839169584, "Hypoglycaemia ": 12.430179345498235, "International normalised ratio increased ": 23.44174657935997, "Pancreatitis acute ": 63.37477913824392}
\ No newline at end of file
+{"Condition aggravated": 2.5670856482066577, "Drug ineffective": 3.1542600755537946, "Drug withdrawal syndrome neonatal": 41.80210790722083, "Encephalopathy": 20.375410411569156, "Epilepsy": 5.661081061762026, "Exposure during pregnancy": 2.4990749426151813, "Foetal exposure during pregnancy": 4.969120428596721, "Infantile spasms": 355.6710013672589, "Magnetic resonance imaging abnormal": 215.38064940058064, "Magnetic resonance imaging head abnormal": 1295.492678923104, "Maternal exposure during pregnancy": 3.5638714753386647, "Neonatal behavioural syndrome": 2147.1499701144967, "Optic atrophy": 206.5678709662796, "Optical coherence tomography abnormal": 3883.8639835737167, "Psychotic disorder": 8.19166123294794, "Retinal disorder": 495.6011520809989, "Retinal toxicity": 363.0742873900012, "Retinogram abnormal": 2065.285641059615, "Seizure": 14.971241000192276, "Status epilepticus": 22.59161791463593, "Therapeutic product effect incomplete": 2.921944205234387, "Toxicity to various agents": 6.297140798308555, "Visual acuity reduced": 16.361061148031908, "Visual field defect": 386.7798912250898}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1166.json
index 78271f32775..988d5324acb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1166.json
@@ -1 +1 @@
-{"Abdominal hernia ": 2.884070979605181, "Abnormal faeces ": 2.3928075408709506, "Abscess limb ": 2.5028862684074333, "Accident ": 6.442149234436229, "Accident at work ": 2.915284670566284, "Acne ": 4.823237463049578, "Animal bite ": 7.165849440569597, "Ankle fracture ": 3.9407655637284713, "Ankylosing spondylitis ": 2.155962418203152, "Anorectal disorder ": 2.31115344831101, "Aortic aneurysm ": 2.023304278173464, "Aphonia ": 2.5106125352909108, "Appendicitis perforated ": 4.250554405590314, "Arthritis ": 4.122558377241598, "Arthritis bacterial ": 3.645172554537759, "Arthritis infective ": 14.23639378974735, "Arthropathy ": 3.1563723529350804, "Arthropod bite ": 4.091048236158095, "Back disorder ": 4.741914452090682, "Back injury ": 2.226458195748169, "Bacterial infection ": 2.4603310213299525, "Basal cell carcinoma ": 3.3918565608485305, "Blindness ": 2.273259630781705, "Blood cholesterol abnormal ": 3.745905280483345, "Blood cholesterol increased ": 4.25225725971097, "Blood iron decreased ": 3.3957232138493585, "Blood pressure abnormal ": 2.2257939788563963, "Blood test abnormal ": 2.919178973710866, "Body height decreased ": 4.109398001371105, "Bone deformity ": 6.158186333180558, "Bone disorder ": 3.235768140362503, "Bowel movement irregularity ": 11.483806760524454, "Breast cancer female ": 7.836133796873424, "Bronchial disorder ": 4.440277029508794, "Bronchitis ": 5.287331104733708, "C-reactive protein decreased ": 3.93774690829397, "C-reactive protein increased ": 3.05852073877237, "Cardiac disorder ": 2.105963671589354, "Carpal tunnel syndrome ": 4.703984029745597, "Cartilage injury ": 4.889307878385795, "Cataract ": 4.189898744413058, "Cellulitis ": 3.846776579850049, "Change of bowel habit ": 3.9299829795286216, "Chest injury ": 4.478265966807984, "Chondropathy ": 5.712299736421428, "Circumstance or information capable of leading to medication error ": 2.4535527370356784, "Clostridium difficile infection ": 4.69433192727976, "Coccidioidomycosis ": 10.420758902287782, "Colectomy ": 13.19966951795343, "Colitis ulcerative ": 11.027221022240488, "Colon cancer ": 2.6405366989759216, "Colon injury ": 14.851118906020046, "Colostomy ": 4.496799654131503, "Concussion ": 2.365106357378839, "Condition aggravated ": 9.220630237333856, "Crohn's disease ": 2.335267815459164, "Cyst ": 4.111349649791503, "Cystitis ": 6.146524586519368, "Deafness ": 2.0885520602808274, "Decreased immune responsiveness ": 10.190129969481374, "Defaecation urgency ": 9.216738208184816, "Dementia ": 2.927416845710002, "Dementia Alzheimer's type ": 3.3009719354619595, "Dental operation ": 6.622210238141171, "Dermatomyositis ": 2.6632195864470702, "Diabetes mellitus ": 2.486357079201282, "Diarrhoea haemorrhagic ": 2.7412488547525813, "Discouragement ": 28.66820406371703, "Disease recurrence ": 4.982286237610257, "Diverticulitis ": 7.399989409912882, "Diverticulum ": 2.3447556565832035, "Drug effect less than expected ": 2.338501716279556, "Drug effective for unapproved indication ": 13.777299223054897, "Drug ineffective ": 2.228030949724445, "Dysgraphia ": 3.483490520546, "Dysstasia ": 2.1322661613748064, "Ear disorder ": 2.5114218597751305, "Ear infection ": 4.161845376917523, "Embolism venous ": 2.696699270163605, "Endometrial cancer ": 2.7481922947055986, "Energy increased ": 3.321596396481136, "Enteritis infectious ": 7.408909309555337, "Escherichia infection ": 2.937576579340351, "Exostosis ": 2.3880460237812327, "Exposure to SARS-CoV-2 ": 3.7078327251033394, "Eye disorder ": 2.0845262123786106, "Eye infection ": 7.880904154230506, "Eye operation ": 4.1889883301279385, "Faecal calprotectin increased ": 26.2301529920589, "Faeces pale ": 2.1374552083152025, "Faeces soft ": 4.561286147344739, "Fall ": 3.057350147136144, "Femur fracture ": 3.299674382000317, "Fibromyalgia ": 2.388502466328929, "Fibula fracture ": 2.261601321933054, "Finger deformity ": 10.230879616240076, "Fistula ": 2.5376580673705207, "Flatulence ": 2.3792070588223178, "Food poisoning ": 3.262190697031319, "Foot deformity ": 7.957466409026718, "Foot fracture ": 3.3521393117748315, "Foot operation ": 7.890907341742226, "Frequent bowel movements ": 10.3280252432236, "Frustration tolerance decreased ": 2.380511762342302, "Functional gastrointestinal disorder ": 2.277295271903678, "Fungal foot infection ": 8.168131865810603, "Fungal infection ": 2.864479121445227, "Furuncle ": 3.8110369997639415, "Gait disturbance ": 2.9117528723951662, "Gait inability ": 4.452290267539713, "Gallbladder disorder ": 2.833626593982784, "Gastric infection ": 8.39149014995089, "Gastric ulcer ": 2.1763801075128164, "Gastroenteritis viral ": 3.5509495755776435, "Gastrointestinal disorder ": 2.2797336788872733, "Gastrointestinal infection ": 3.57286524457515, "Gastrointestinal perforation ": 4.026268233561218, "Glaucoma ": 2.380241545511129, "Grip strength decreased ": 3.4731940380903303, "Haematochezia ": 8.015235406559377, "Haemorrhoids ": 2.015264038644923, "Hair growth abnormal ": 2.56609689130473, "Hand fracture ": 2.341637076322997, "Hernia ": 5.032829561481814, "Herpes ophthalmic ": 5.476988279062687, "Herpes virus infection ": 2.4900287144035707, "Herpes zoster ": 3.829311634892809, "Herpes zoster disseminated ": 4.146013822175415, "Hip arthroplasty ": 2.7120839709362485, "Hip fracture ": 4.684246613409992, "Hip surgery ": 5.592309278149666, "Hordeolum ": 3.00115072256945, "Hypoacusis ": 4.139054976746869, "Hypokinesia ": 2.070400302209489, "Ileostomy ": 7.214297757967563, "Illness ": 5.488495275281959, "Immune system disorder ": 6.306799815583306, "Immunodeficiency ": 3.000297820661051, "Immunosuppression ": 11.315393917453394, "Impaired healing ": 2.265580348416136, "Impaired quality of life ": 3.168956449872104, "Increased tendency to bruise ": 2.4482946489636968, "Infected bite ": 9.528866665780384, "Infected skin ulcer ": 8.246921635446991, "Infection ": 5.05538045120217, "Inflammation ": 3.0932182395958705, "Inflammatory bowel disease ": 2.799415557771757, "Inflammatory marker increased ": 4.328035945001187, "Influenza ": 2.5377032796983707, "Intentional dose omission ": 10.244864731010944, "Intentional product misuse ": 4.37964386306572, "Intentional product use issue ": 2.154031897911602, "Intervertebral disc degeneration ": 2.401744988660555, "Intervertebral disc disorder ": 2.681178559619572, "Intervertebral disc protrusion ": 3.77022404723309, "Intestinal perforation ": 2.9457518964826828, "Intestinal resection ": 3.5075153490474387, "Intracranial aneurysm ": 2.280947130126161, "Joint abscess ": 21.03533617693567, "Joint destruction ": 4.925112803632064, "Joint dislocation ": 5.646604246621957, "Joint effusion ": 4.046440701763593, "Joint injury ": 6.666711606733356, "Joint lock ": 4.297733580675227, "Joint noise ": 3.4604514031083955, "Joint range of motion decreased ": 3.316824384480165, "Joint stiffness ": 2.5559959006934543, "Joint swelling ": 3.287765766670077, "Kidney infection ": 9.231758312758531, "Knee arthroplasty ": 5.018296032129474, "Knee deformity ": 5.358948337671149, "Knee operation ": 11.376002177893408, "Laboratory test abnormal ": 2.733926354084012, "Lactose intolerance ": 2.913422612802192, "Large intestine infection ": 4.497342833521244, "Laryngitis ": 4.792477064733623, "Latent tuberculosis ": 4.353631065577561, "Ligament rupture ": 7.581175158983913, "Ligament sprain ": 4.783110454910474, "Limb injury ": 6.265018893940134, "Limb mass ": 3.554656696907944, "Limb operation ": 7.807236902522109, "Lipids increased ": 3.841642055216963, "Localised infection ": 9.295619806565076, "Loss of personal independence in daily activities ": 3.2566380396750985, "Loss of therapeutic response ": 4.603716714473935, "Low density lipoprotein increased ": 2.610811890157499, "Lower limb fracture ": 5.522633434697309, "Lower respiratory tract infection ": 7.2083470458330545, "Lumbar spinal stenosis ": 2.5029672295770595, "Lung carcinoma cell type unspecified stage IV ": 3.837127476170201, "Lung disorder ": 2.714603459551626, "Lung neoplasm malignant ": 3.0002753876117234, "Lyme disease ": 4.507230549518414, "Lymphocyte count decreased ": 2.131806248967955, "Lymphoma ": 4.034631811242523, "Malignant melanoma ": 2.5408563090460943, "Mean cell haemoglobin decreased ": 2.676231691943449, "Memory impairment ": 2.848906966970412, "Meniscus injury ": 5.274771973456831, "Middle insomnia ": 2.046899917943348, "Mobility decreased ": 2.66992969279505, "Mucous stools ": 12.605678648686649, "Muscle rupture ": 4.239719702411953, "Muscle strain ": 4.129407348025351, "Musculoskeletal discomfort ": 2.547961877215986, "Musculoskeletal disorder ": 3.435690119569411, "Musculoskeletal stiffness ": 3.2104209048186707, "Mutism ": 2.483974516899671, "Mycobacterial infection ": 2.372770725834075, "Mycobacterium tuberculosis complex test positive ": 4.208125136182243, "Nail infection ": 9.919580006167063, "Nasal congestion ": 2.8640900645122964, "Nasopharyngitis ": 5.251160202437409, "Near death experience ": 2.683142016735039, "Neck surgery ": 5.403019961580301, "Neoplasm ": 2.5127221610796884, "Neoplasm malignant ": 3.900035231921756, "Nephrolithiasis ": 3.671263112618825, "Nerve compression ": 7.295610284416162, "Neuroendocrine carcinoma of the skin ": 5.985781662082982, "Nodule ": 4.307214026731338, "Onychomycosis ": 2.090557649308347, "Ophthalmic herpes zoster ": 4.47859278818176, "Oral herpes ": 2.901829524858127, "Oral infection ": 4.855985979106284, "Oral surgery ": 6.936227928532146, "Osteitis ": 2.3810781968613, "Osteoarthritis ": 6.08990563761232, "Osteomyelitis ": 4.74128264592438, "Pain ": 2.081006176716522, "Pancreatic disorder ": 2.159102279470577, "Parkinson's disease ": 2.0725179632364497, "Patella fracture ": 4.412541845948415, "Pelvic fracture ": 8.05332095859515, "Peripheral swelling ": 2.7673379784818533, "Pharyngeal disorder ": 3.304762953454073, "Pharyngitis streptococcal ": 8.588485839355084, "Plantar fasciitis ": 2.57610753350694, "Pneumonia ": 4.146151799625604, "Pneumonia bacterial ": 2.170113859780184, "Pneumonia fungal ": 2.659072250323589, "Polyarthritis ": 2.855226304939351, "Polyp ": 3.879668448788496, "Post procedural complication ": 4.0430533651762, "Post procedural infection ": 9.684732945782804, "Postoperative wound infection ": 5.953531238236739, "Pre-existing condition improved ": 11.386047523066978, "Precancerous skin lesion ": 7.302423076228181, "Product administration interrupted ": 3.620536614562346, "Product dispensing error ": 4.14149329496209, "Product dispensing issue ": 10.82425487424132, "Product dose omission in error ": 29.36672245036584, "Product dose omission issue ": 4.910272176230133, "Product prescribing error ": 3.9116832129130055, "Product prescribing issue ": 4.481664173472336, "Product use issue ": 2.051342810626262, "Pulmonary fibrosis ": 2.2105525860488893, "Pulmonary mass ": 2.1888785552435923, "Pulmonary thrombosis ": 4.894800127737206, "Pyelonephritis acute ": 2.029372542820046, "Rectal haemorrhage ": 3.4501137642808084, "Red blood cell sedimentation rate increased ": 7.057728448592082, "Red cell distribution width increased ": 3.271684946576185, "Renal disorder ": 2.0332118673671187, "Respiratory tract congestion ": 3.1055729765434616, "Respiratory tract infection ": 5.279892682188207, "Rheumatoid arthritis ": 9.684068297605616, "Rheumatoid factor increased ": 4.314748161567954, "Rheumatoid lung ": 15.22532435086121, "Rheumatoid nodule ": 3.206396668823501, "Rhinorrhoea ": 2.3054221947515545, "Rib fracture ": 4.5029789902352455, "Road traffic accident ": 2.4557194737462376, "Root canal infection ": 15.596516280448414, "Rosacea ": 3.603283907128744, "Rotator cuff repair ": 7.315733578436119, "Rotator cuff syndrome ": 3.5603245042153384, "Sciatica ": 3.3862265188673946, "Seasonal allergy ": 2.3212835767437463, "Secretion discharge ": 2.0137728171923617, "Sensitivity to weather change ": 74.79239676759381, "Serum ferritin decreased ": 4.377714024717936, "Shoulder arthroplasty ": 6.910809620132806, "Shoulder fracture ": 5.785637192367399, "Shoulder operation ": 7.963545249038041, "Sinus congestion ": 3.0791369909766315, "Sinus disorder ": 5.123468849937683, "Sinusitis ": 5.764374498323321, "Sinusitis bacterial ": 11.755807438517715, "Sjogren's syndrome ": 5.333683861475484, "Skin cancer ": 12.087827958796744, "Skin infection ": 5.163054535036357, "Skin laceration ": 2.1743684834052988, "Skin lesion ": 2.1867895003365008, "Skin papilloma ": 2.422605519046233, "Spinal column injury ": 2.1681627589116794, "Spinal disorder ": 5.826334056620661, "Spinal fracture ": 4.879635386933575, "Spinal fusion surgery ": 4.389588832457066, "Spinal operation ": 8.364108399666158, "Spinal osteoarthritis ": 2.2351817474495044, "Spinal stenosis ": 4.517192979728206, "Spondylitis ": 3.2989709352108663, "Squamous cell carcinoma ": 2.99282341411217, "Squamous cell carcinoma of skin ": 2.87892501999679, "Staphylococcal infection ": 3.131550994475061, "Stress ": 4.406089547947764, "Stress fracture ": 3.172593327144537, "Synovial cyst ": 7.054134386319614, "Synovitis ": 2.197546493024581, "Therapeutic product effect delayed ": 12.894914124803362, "Therapeutic product effect incomplete ": 10.417660906176646, "Therapeutic response shortened ": 3.0174436655285883, "Therapeutic response unexpected ": 4.032725508487449, "Thrombosis ": 2.900543624967113, "Tibia fracture ": 2.723597235907611, "Tooth abscess ": 12.1726670781839, "Tooth disorder ": 2.827571185794042, "Tooth infection ": 9.754547732061573, "Trigger finger ": 8.09978296135574, "Tuberculin test positive ": 4.125715514569197, "Tuberculosis ": 6.060448717697112, "Ulcer ": 2.081045508166849, "Upper limb fracture ": 5.47997362201795, "Upper respiratory tract congestion ": 3.7915813868841135, "Upper respiratory tract infection ": 4.699784227846555, "Urinary tract infection ": 5.311379665112381, "Urinary tract infection bacterial ": 5.656062041954677, "Vaginal infection ": 2.2908939980981144, "Vein rupture ": 3.354917183704217, "Viral infection ": 4.501724042068621, "Viral upper respiratory tract infection ": 4.731834105090763, "Vitamin D decreased ": 3.325154002157109, "Walking aid user ": 2.885538718455632, "Weight fluctuation ": 2.109185385587176, "Weight increased ": 2.4089663270010178, "Wound infection ": 6.106069231784663, "Wound secretion ": 4.196760124655299, "Wrist fracture ": 3.844355607509263, "Wrong dose ": 2.282167278670006}
\ No newline at end of file
+{"Blister": 8.470375359176595, "Blood creatine phosphokinase increased": 5.777031937086752, "Blood glucose increased": 2.83613018404912, "Blood phosphorus increased": 65.6311665791848, "Bradycardia": 2.725012367964736, "Coma": 5.755527578245456, "Diabetes mellitus inadequate control": 17.407003863466525, "Drug interaction": 3.542857902475625, "Glycosylated haemoglobin increased": 9.115781457933426, "Hepatic function abnormal": 2.248476036411119, "Hepatitis": 7.64271220380885, "Hyperglycaemia": 3.876675118939951, "Hyperkalaemia": 3.996152017181709, "Hypocalcaemia": 20.615279119395343, "Hypoglycaemia": 11.471448202273892, "Hypoglycaemic coma": 17.5055450558708, "Hypomagnesaemia": 29.407481795694157, "Hypoparathyroidism": 382.4531151659439, "Intentional overdose": 4.282044848885023, "Jaundice": 4.110742156128029, "Lactic acidosis": 11.333772610235249, "Metabolic acidosis": 8.964177702938553, "Pancreatitis acute": 15.667470033671016, "Pemphigoid": 350.16633668975106, "Renal impairment": 5.058941146568038, "Rhabdomyolysis": 3.732917095042711, "Syncope": 4.616215246906478, "Ventricular tachycardia": 26.00611653007701}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1167.json
index 7d24bdd45d3..eb01cdcaae6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1167.json
@@ -1 +1 @@
-{"Angina pectoris ": 2.2384108583098943, "Blood bilirubin increased ": 2.362730285734237, "Cardiotoxicity ": 8.364532985830472, "Colitis ": 2.2421253890274877, "Cytopenia ": 3.4056755886808654, "Decreased appetite ": 3.037550371822953, "Dehydration ": 5.500518065546097, "Diarrhoea ": 5.185923765483005, "Dihydropyrimidine dehydrogenase deficiency ": 558.2720644150886, "Disease progression ": 3.4205536594812105, "Disseminated intravascular coagulation ": 4.980523480836592, "Drug interaction ": 3.062848114406834, "Drug-induced liver injury ": 2.481271883611569, "Enteritis ": 13.7171912538231, "Enterocolitis ": 15.604784290694685, "Faecal volume decreased ": 255.86707061670367, "Febrile neutropenia ": 4.032253310476976, "Formication ": 4.762352058622428, "Gastrointestinal disorder ": 2.898946129614268, "Granulocyte count decreased ": 20.84968282235198, "Granulocytopenia ": 9.202547515220974, "Hepatic function abnormal ": 6.779865604880881, "Hepatic lesion ": 9.691426315849826, "Hyperbilirubinaemia ": 3.171059135469399, "Ileus ": 5.047902978645126, "Intentional product use issue ": 2.107817980361163, "International normalised ratio increased ": 4.347527932144155, "Interstitial lung disease ": 2.612142748915216, "Intestinal obstruction ": 2.724589771920116, "Leukoencephalopathy ": 12.439607280393512, "Leukopenia ": 3.282350316287402, "Liver injury ": 2.1875435848493927, "Metastases to liver ": 2.7565281006463964, "Mouth ulceration ": 2.1701152747591235, "Mucosal inflammation ": 12.440914443245743, "Myelosuppression ": 58.189299880052815, "Neuropathy peripheral ": 5.415522268494856, "Neurotoxicity ": 7.1808520378960266, "Neutropenia ": 6.094062686874297, "Neutrophil count decreased ": 15.836277166201668, "Palmar-plantar erythrodysaesthesia syndrome ": 21.2059160599237, "Pancytopenia ": 3.3775782223168496, "Platelet count decreased ": 18.03954869374636, "Polyneuropathy ": 3.27974274011786, "Prothrombin time prolonged ": 8.384464030534312, "Retching ": 2.153909571237612, "Sensory disturbance ": 2.5989980533656034, "Sepsis ": 2.075543772288573, "Septic shock ": 3.3915362479540616, "Stomatitis ": 5.051706541413796, "Thrombocytopenia ": 4.976672853500907, "Vomiting ": 2.9144658389496474, "White blood cell count decreased ": 12.905969957567365}
\ No newline at end of file
+{"Abnormal behaviour": 4.281961212219553, "Abortion induced": 4.636131950338319, "Accidental exposure to product": 4.240859210788143, "Affective disorder": 3.776545546033588, "Aggression": 7.013525434769154, "Agitation": 3.1788310313852857, "Agranulocytosis": 2.426673470568219, "Altered state of consciousness": 2.4306724795353998, "Amnesia": 4.040217485068628, "Anger": 3.642161823997201, "Anticonvulsant drug level increased": 12.554149828038058, "Apathy": 2.0269299023052576, "Aphasia": 2.7496770209476336, "Ataxia": 6.340599246525355, "Atrial fibrillation": 2.008976241982691, "Atrial flutter": 3.4506883187713835, "Atrioventricular block": 17.732712575178837, "Atrioventricular block complete": 16.681126822021746, "Atrioventricular block first degree": 9.6620518278023, "Atrioventricular block second degree": 23.20596074028522, "Aura": 26.866118462741696, "Balance disorder": 5.726606707078292, "Behaviour disorder": 3.726300388674943, "Bipolar disorder": 3.416398787187151, "Bradycardia": 6.330814537282234, "Brain neoplasm": 10.307494621460648, "Brain operation": 50.2115798337618, "Caesarean section": 5.660992204909679, "Cardiac pacemaker insertion": 6.16087547004473, "Change in seizure presentation": 109.98365812863648, "Cognitive disorder": 4.782300514816201, "Coordination abnormal": 6.827824129920297, "Delusion": 2.5948779157056894, "Depression": 2.169498110922961, "Developmental delay": 4.750528823758352, "Diplopia": 14.679877043416138, "Drop attacks": 21.328565401013428, "Drug eruption": 2.218860511221159, "Drug reaction with eosinophilia and systemic symptoms": 3.8735614484050793, "Dysarthria": 2.353309594413144, "Dyskinesia": 2.377223616214762, "Dysmorphism": 6.3371493952647295, "Electrocardiogram PR prolongation": 51.93661217876928, "Electroencephalogram abnormal": 9.860301414622144, "Encephalitis": 2.0739166053675566, "Encephalopathy": 3.95509993170344, "Epilepsy": 25.420998187503887, "Fall": 2.861954173034016, "Feeling drunk": 3.626686513189072, "Focal dyscognitive seizures": 32.42546357454082, "Gait disturbance": 2.310732663105475, "Generalised tonic-clonic seizure": 18.054479368923, "Hallucination": 2.0653796496900183, "Hallucination, auditory": 3.284362503392343, "Hallucination, visual": 2.800729348188799, "Head injury": 5.443299115673567, "Hospitalisation": 3.5551924961600005, "Inability to afford medication": 15.869477421325698, "Inappropriate schedule of product administration": 3.0583068445172046, "Intentional product misuse": 2.171438806846552, "Irritability": 4.579239420117863, "Maternal exposure before pregnancy": 23.43509053558697, "Maternal exposure during breast feeding": 3.756021888934713, "Maternal exposure during pregnancy": 6.051934033251827, "Memory impairment": 3.4185507630444425, "Mental disorder": 2.702442678953964, "Mood altered": 2.6923124794718207, "Mood swings": 2.494658604364797, "Multiple-drug resistance": 6.261785591153815, "Myoclonic epilepsy": 17.582460393016248, "Myoclonus": 6.765741841462612, "No adverse event": 2.1066351862654185, "Nystagmus": 7.102562501107253, "Off label use": 4.113137917868049, "Overdose": 4.611095916495148, "Paranoia": 2.999011153345502, "Partial seizures": 22.32943163219125, "Partial seizures with secondary generalisation": 47.58366789819265, "Petit mal epilepsy": 26.92714130644329, "Pneumonia aspiration": 5.463928137418055, "Pregnancy": 2.668376815105756, "Prescribed underdose": 2.582923215234883, "Product administration error": 2.1302545740166714, "Product availability issue": 6.260828099343911, "Psychotic disorder": 5.068324218192024, "Screaming": 3.666126751812902, "Sedation": 2.979379989058401, "Seizure": 16.70242083141531, "Seizure cluster": 40.73193805559014, "Sinus arrest": 11.929946652569347, "Sinus bradycardia": 5.197284563639514, "Sinus node dysfunction": 31.477807612871057, "Sluggishness": 4.189586734818063, "Somnolence": 4.072397591486928, "Staring": 8.219892698013998, "Status epilepticus": 22.31444620132796, "Stevens-Johnson syndrome": 2.080520459582734, "Sudden unexplained death in epilepsy": 95.01405375128653, "Suicidal ideation": 5.340918290497152, "Suicide attempt": 3.241727123380294, "Therapeutic product ineffective": 11.11257082977158, "Therapeutic response unexpected": 2.2983915736907807, "Therapy interrupted": 8.308937075724902, "Treatment noncompliance": 3.520220791017492, "Underdose": 3.126602007759616, "Ventricular fibrillation": 2.128275978840651, "Vertigo": 3.5528358129278304, "Vision blurred": 2.6483250451990625, "Wrong technique in product usage process": 2.2456317062}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1168.json
index cff584ea66e..cb922e8911c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1168.json
@@ -1 +1 @@
-{"Drug interaction ": 32.58711593822185, "Drug level decreased ": 155.18513374722136, "International normalised ratio increased ": 19.50159743590104, "Renal failure ": 2.9713598274169324}
\ No newline at end of file
+{"Foetal exposure during pregnancy": 20.004843570465844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1169.json
index 72bd17c9d75..33808e08d0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1169.json
@@ -1 +1 @@
-{"Completed suicide ": 4.033331950118586, "Drug interaction ": 2.736196017149354, "Electrocardiogram QT prolonged ": 6.694905452022044, "Extrapyramidal disorder ": 53.19828458071488, "Neuroleptic malignant syndrome ": 37.12060238203841, "Overdose ": 2.8464849965704224, "Product use in unapproved indication ": 2.3756402356931456, "Psychiatric symptom ": 61.4738604159204, "Psychotic disorder ": 20.386707798002, "Restlessness ": 8.8291692842702, "Rhabdomyolysis ": 11.90145791408296, "Schizophrenia ": 108.64342338680372, "Suicidal ideation ": 4.61463585452843, "Suicide attempt ": 7.852130505708266, "Weight increased ": 4.929064803427889}
\ No newline at end of file
+{"Acute hepatic failure": 18.76939921792588, "Alanine aminotransferase increased": 4.914150141272623, "Ascites": 6.555868611360491, "Aspartate aminotransferase increased": 3.878041316451128, "Blood alkaline phosphatase increased": 3.955033721033424, "Blood bilirubin increased": 5.303939711692982, "Blood creatine phosphokinase increased": 2.801894823126513, "Blood lactate dehydrogenase increased": 4.683304377800899, "Cholestasis": 4.318429006362471, "Conjunctivitis": 7.450527180532714, "Drug eruption": 2.441888774818128, "Drug reaction with eosinophilia and systemic symptoms": 4.317324225377931, "Drug resistance": 6.119840934414189, "Eosinophilia": 7.086952592395356, "Erythema multiforme": 3.425540464276031, "Foetal exposure during pregnancy": 2.4677831812204265, "Gamma-glutamyltransferase increased": 8.272662946028708, "Hepatic cirrhosis": 6.312214284861156, "Hepatic cytolysis": 5.169643190242111, "Hepatic enzyme increased": 5.354667022882833, "Hepatic failure": 16.531134540057057, "Hepatic necrosis": 25.42466373157117, "Hepatitis": 28.122670851311444, "Hepatitis acute": 9.148280883816811, "Hepatitis cholestatic": 21.38444524199395, "Hepatitis fulminant": 33.2294897419774, "Hepatitis toxic": 18.58154531849236, "Hepatotoxicity": 17.558247300172678, "Hypersensitivity": 2.727478208548566, "Jaundice": 14.291736992269046, "Lactic acidosis": 3.731626853255287, "Liver function test abnormal": 16.01907328745246, "Liver function test increased": 6.119552773167825, "Mouth ulceration": 5.449754130300336, "Mucosal inflammation": 3.400807573853644, "Pancreatitis": 3.915676478387241, "Pregnancy": 17.038471055472254, "Premature baby": 2.8678991685492417, "Product residue present": 44.68375910299325, "Pulmonary oedema": 2.8201162941153752, "Rash": 4.934368723664584, "Rash erythematous": 2.342529101630762, "Rash macular": 2.817503696732849, "Rash maculo-papular": 15.258290759774964, "Rash papular": 3.747272673299469, "Stevens-Johnson syndrome": 69.85535057626883, "Toxic epidermal necrolysis": 21.714389466617284, "Transaminases increased": 5.905342404948623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/117.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/117.json
index 96e50ddf04c..ca8761d20f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/117.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/117.json
@@ -1 +1 @@
-{"Neutropenia ": 26.723945494716958, "Pyrexia ": 3.738393341933047}
\ No newline at end of file
+{"Abortion induced": 4.15209150401844, "Acute kidney injury": 2.023143407567439, "Adrenal insufficiency": 7.977183697237856, "Alanine aminotransferase increased": 2.5044205502290144, "Alcohol abuse": 6.643004836640713, "Anxiety": 5.119797075918338, "Aspartate aminotransferase increased": 2.362524204713081, "Ataxia": 3.9308349223795833, "Atypical mycobacterial infection": 32.03969101856278, "Blood HIV RNA increased": 28.75277365359353, "Blood bilirubin increased": 10.421517124373574, "Blood corticotrophin decreased": 54.71832424687673, "Blood creatinine increased": 2.094927139699865, "Blood lactic acid increased": 11.722222357689844, "Blood phosphorus decreased": 10.958902756132234, "Blood triglycerides increased": 6.3699527425974525, "CD4 lymphocytes decreased": 11.570625021445732, "CSF HIV escape syndrome": 2393.356414907418, "Caesarean section": 16.08058716161095, "Calculus urinary": 12.824482116299878, "Castleman's disease": 59.08808077936829, "Cholelithiasis": 3.727690551645369, "Cholestasis": 2.390505249997665, "Conduction disorder": 21.73009974998799, "Cortisol decreased": 36.97748983346886, "Cushing's syndrome": 59.00350200062468, "Cushingoid": 29.337088879657284, "Depression": 16.764418731610114, "Depression suicidal": 440.7440140627151, "Depressive symptom": 237.29125368986715, "Diplegia": 7.3721153860807, "Diplopia": 5.3712663114681645, "Drug interaction": 20.12716411764576, "Drug level increased": 6.195155478144248, "Drug resistance": 14.081894325936908, "Ergot poisoning": 132.4653258454617, "Eyelid ptosis": 24.27989063167037, "Fanconi syndrome": 11.121018052112126, "Fanconi syndrome acquired": 7.450321314227036, "Feeling jittery": 8.56573813086154, "Foetal exposure during delivery": 37.38641258305063, "Foetal exposure during pregnancy": 5.005933676692155, "Glomerular filtration rate decreased": 3.496509708654596, "Goitre": 7.945945091322272, "Graves' disease": 7.175737360602633, "Haematuria": 2.486970427047161, "Haemolytic anaemia": 4.044724005953814, "Hepatomegaly": 2.527580901033091, "Herpes simplex": 9.302641643753446, "Hiatus hernia": 3.606805955286504, "Hyperbilirubinaemia": 38.13914183583642, "Hypercholesterolaemia": 2.438544567228293, "Hyperlipidaemia": 11.279086682793192, "Hypertriglyceridaemia": 6.206320518524291, "Hypophosphataemia": 5.92117155958121, "Immune reconstitution inflammatory syndrome": 51.894146825582986, "Jaundice": 12.4303862812158, "Kaposi's sarcoma": 52.27086451743866, "Labelled drug-drug interaction medication error": 2.974460570869642, "Lipoatrophy": 46.7551719328593, "Lipodystrophy acquired": 61.81413290675173, "Lipohypertrophy": 22.056573760384374, "Live birth": 6.584842355100015, "Loss of personal independence in daily activities": 6.755596125308069, "Low birth weight baby": 4.713960210523822, "Maternal exposure during pregnancy": 4.276272077788864, "Meningitis cryptococcal": 24.840327310770174, "Mitochondrial toxicity": 116.359756997996, "Mycobacterium avium complex infection": 18.570707364427506, "Nephrolithiasis": 7.954052272006041, "Nephropathy toxic": 6.15629814904412, "No adverse event": 2.231708522086153, "Normal newborn": 14.064398786905986, "Ocular icterus": 11.08706605602628, "Oesophageal candidiasis": 10.043197559554718, "Oesophageal varices haemorrhage": 9.79834601501519, "Ophthalmoplegia": 36.32107323568782, "Opportunistic infection": 24.372926836917816, "Oropharyngeal candidiasis": 25.99272725047675, "Paranoia": 99.44991154707223, "Parkinsonism": 2.6660025180205214, "Pathogen resistance": 17.20099959079484, "Pelvic pain": 2.287802065430796, "Peripheral sensory neuropathy": 5.236181018429772, "Petit mal epilepsy": 4.9772506643692775, "Pneumocystis jirovecii pneumonia": 3.2413950833732352, "Premature baby": 2.870238485026556, "Premature delivery": 6.811636044537971, "Premature rupture of membranes": 32.33386297130203, "Prescribed overdose": 4.219392227827703, "Product use in unapproved indication": 3.757814277560218, "Progressive multifocal leukoencephalopathy": 11.75741901625023, "Proteinuria": 2.7311007328437404, "Psychiatric decompensation": 863.8107365301199, "Psychomotor retardation": 40.66560513169935, "Psychomotor skills impaired": 301.8093503692099, "Psychotic disorder": 41.68580595207388, "Rales": 4.205662357104036, "Renal aplasia": 32.286381991134014, "Renal colic": 6.481790813694071, "Renal dysplasia": 67.51693748792914, "Renal tubular disorder": 5.915773150942504, "Renal tubular dysfunction": 18.06212367267128, "Renal tubular necrosis": 7.595659462682406, "Sinus bradycardia": 2.1889202451268, "Suicidal ideation": 13.928512165295658, "Tearfulness": 274.49272737447063, "Torsade de pointes": 4.29683847919913, "Treatment failure": 3.569479142798458, "Treatment noncompliance": 9.78315990389932, "Tubulointerstitial nephritis": 5.014907065980238, "Type 1 diabetes mellitus": 3.222750840698257, "Viral load increased": 24.18031807008479, "Viral mutation identified": 64.95070160605133, "Virologic failure": 103.8921721481632}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1170.json
index 469bc192700..e67be4dfd8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1170.json
@@ -1 +1 @@
-{"Diarrhoea ": 8.022891568732133}
\ No newline at end of file
+{"Acute kidney injury": 6.391687157265298, "Alanine aminotransferase increased": 2.1396171183624624, "Amylase increased": 4.285906087678335, "Anhedonia": 20.621645383123106, "Ankle fracture": 8.570846317041044, "Anxiety": 5.714051501038864, "Azotaemia": 6.17060581069334, "Blood creatinine abnormal": 10.09269997643117, "Blood creatinine increased": 10.32024122744794, "Blood lactic acid increased": 3.920168711991569, "Blood phosphorus decreased": 57.434493122318216, "Blood urea increased": 2.15818720768301, "Bone demineralisation": 19.189644575770068, "Bone density abnormal": 8.572696541278924, "Bone density decreased": 17.818182053264678, "Bone disorder": 8.314844943384319, "Bone loss": 15.37925182188718, "Bone pain": 2.7399374512305257, "CD4 lymphocytes decreased": 10.5701402684543, "Chronic kidney disease": 21.520083417146942, "Creatinine renal clearance decreased": 12.033136367273626, "Decreased activity": 6.932719736180123, "Drug resistance": 4.757009853657179, "Economic problem": 21.96826897371798, "Emotional distress": 18.20795610370266, "End stage renal disease": 34.05433917524757, "Fanconi syndrome": 114.53323562815063, "Fanconi syndrome acquired": 159.86361809160002, "Femur fracture": 5.714946019178719, "Foetal death": 2.3081138750572574, "Foot fracture": 8.63491394805124, "Fracture": 11.318158613347029, "Genotype drug resistance test positive": 18.85327797861016, "Glomerular filtration rate abnormal": 8.336870075297226, "Glomerular filtration rate decreased": 7.780712543780693, "Glycosuria": 46.00087635976696, "Hepatic cancer": 2.784639777042697, "Hepatic cirrhosis": 4.001487236745732, "Hepatic failure": 2.6300231830330025, "Hepatitis B": 8.142364790830603, "Hepatitis B DNA assay positive": 254.68624259722085, "Hepatitis B DNA increased": 150.2480570451599, "Hepatitis B reactivation": 14.49678923427908, "Hepatocellular carcinoma": 2.336098690931376, "Hip fracture": 5.453202905620159, "Hypocalcaemia": 2.323657612204268, "Hypophosphataemia": 70.21664773013512, "Hypophosphataemic osteomalacia": 118.74644814920156, "Immune reconstitution inflammatory syndrome": 10.533889057586588, "Intervertebral disc degeneration": 3.236502444989977, "Lactic acidosis": 5.014528573869841, "Lipase increased": 3.8011608575206366, "Loss of personal independence in daily activities": 2.139403117010488, "Lower limb fracture": 3.7160225128186983, "Metabolic acidosis": 3.2378047216976333, "Mitochondrial cytopathy": 34.07459120981709, "Multiple fractures": 15.613076504346932, "Nephrogenic diabetes insipidus": 21.26200462109204, "Nephrolithiasis": 4.138736697656153, "Nephropathy": 12.039688814163268, "Nephropathy toxic": 16.632416206986555, "Nephrotic syndrome": 3.0242179030742102, "Osteoarthritis": 2.467252235641249, "Osteomalacia": 68.067425460411, "Osteonecrosis": 15.360986277732517, "Osteopenia": 22.847655999828397, "Osteoporosis": 22.156577081776984, "Pain": 2.7221515444180184, "Pathological fracture": 17.89257424991074, "Polydipsia": 4.57582520644142, "Polyuria": 3.669147609982113, "Pregnancy": 4.715708925021231, "Protein total abnormal": 15.633383854024098, "Proteinuria": 13.078849431429168, "Quality of life decreased": 8.559122373653844, "Renal cyst": 3.4733137808356984, "Renal disorder": 2.888135227287604, "Renal failure": 15.05628439390915, "Renal impairment": 6.310866433041668, "Renal injury": 16.73859373631145, "Renal transplant": 11.51444411457478, "Renal tubular acidosis": 48.93393444774176, "Renal tubular disorder": 58.145386047958354, "Renal tubular dysfunction": 178.77414151084986, "Renal tubular necrosis": 23.450904354446305, "Rib fracture": 7.506233451525775, "Skeletal injury": 17.918695881925714, "Spinal compression fracture": 6.488513385059476, "Spinal fracture": 3.3640297252950155, "Spinal osteoarthritis": 4.147915273253359, "Tibia fracture": 6.192673703728704, "Tooth fracture": 8.76327400373845, "Tooth loss": 12.845982061748348, "Treatment noncompliance": 2.872559235244783, "Tubulointerstitial nephritis": 6.433778344184137, "Upper limb fracture": 2.5726813399254023, "Viral load increased": 62.40505438352553, "Virologic failure": 8.64454321459482, "Vitamin D deficiency": 5.256331873717271, "Wrist fracture": 8.21730543076955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1171.json
index 4d9cb7e2c16..d8c1a7a00e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1171.json
@@ -1 +1 @@
-{"Back pain ": 2.935845632824664, "Hot flush ": 10.009537814005284, "Hypocalcaemia ": 45.58729986690024, "Malignant neoplasm progression ": 7.224431708774694, "Metastases to bone ": 23.43139547256248, "Osteonecrosis of jaw ": 189.02555822628665, "Prostatic specific antigen increased ": 76.98881335539022}
\ No newline at end of file
+{"Acute kidney injury": 9.884150363536811, "Blood creatinine increased": 13.879377033623626, "Drug ineffective": 4.015208808630079, "Drug ineffective for unapproved indication": 517.485225236522, "Neutropenia": 5.456090081111243, "Off label use": 8.073455040483617, "Renal failure": 4.997215000637539}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1172.json
index 90b823e47d8..8b9621db034 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1172.json
@@ -1 +1 @@
-{"Dupuytren's contracture ": 1015.0574975032964, "Haematoma ": 29.5885108338494, "Hypersensitivity ": 3.46007082119764, "Pain in extremity ": 2.0482966017415256, "Penile contusion ": 5477.844931612342, "Penile haematoma ": 2783.614869252263, "Penile pain ": 436.1699933696145, "Penile swelling ": 1571.5565979304415, "Peripheral swelling ": 6.27675194293081, "Skin laceration ": 81.29900011033402, "Tendon rupture ": 100.7051940880498}
\ No newline at end of file
+{"Actinic keratosis": 83.87006766051883, "Acute hepatic failure": 2.5856632098605936, "Acute respiratory distress syndrome": 3.789822796196181, "Adrenal insufficiency": 2.0674348526239985, "Agitation": 2.004671025241877, "Alanine aminotransferase increased": 3.2081831815878634, "Altered state of consciousness": 2.107890333258095, "Aspartate aminotransferase increased": 2.587810809898663, "Aspergillus infection": 57.90992094083037, "Blood alkaline phosphatase increased": 7.136350447736459, "Blood bilirubin increased": 2.3244721819495124, "Brain abscess": 24.318992157061302, "Bronchopulmonary aspergillosis": 56.17052401359245, "Candida infection": 9.04924073335292, "Chloropsia": 127.34994018849072, "Cholestasis": 9.493769963397629, "Chromatopsia": 31.27365558416451, "Condition aggravated": 2.8745137952545097, "Corneal perforation": 45.04785603545755, "Delirium": 11.0079677980353, "Dermatitis bullous": 3.087547490244901, "Dermatitis exfoliative": 6.540864814234395, "Disease progression": 3.05463665182331, "Disorganised speech": 64.52847963130108, "Drug ineffective": 4.267771358872081, "Drug ineffective for unapproved indication": 12.449654114990109, "Drug interaction": 8.643786093496121, "Drug level above therapeutic": 30.833456662155744, "Drug level below therapeutic": 104.16445050301728, "Drug level decreased": 26.564999521990018, "Drug level increased": 19.49937869865424, "Drug resistance": 16.994754019021116, "Drug-induced liver injury": 16.486967038821305, "Dyschromatopsia": 31.31668213202654, "Dysphoria": 3.042502860717484, "Electrocardiogram QT prolonged": 7.561895174704058, "Electrolyte imbalance": 3.933001171890683, "Encephalopathy": 3.177670781034009, "Endophthalmitis": 3.649767260934433, "Eye disorder": 3.290277163194757, "Fluoride increased": 921.6795302682484, "Fluorosis": 1698.8237236018088, "Fungaemia": 17.673646397854935, "Fungal infection": 10.188354554892197, "Fusarium infection": 70.60356992255576, "Gamma-glutamyltransferase increased": 4.5742565337314405, "Haemoptysis": 3.313785930625285, "Hallucination": 22.376448887865354, "Hallucination, auditory": 12.79315998657443, "Hallucination, visual": 44.81446573287334, "Hallucinations, mixed": 14.197228302801186, "Halo vision": 56.02069897689224, "Hepatic cytolysis": 5.309468917463771, "Hepatic enzyme increased": 5.125327474188579, "Hepatic failure": 2.309191565203176, "Hepatic function abnormal": 10.931019075800709, "Hepatitis": 2.4983580605679574, "Hepatitis cholestatic": 4.952749714864956, "Hepatocellular injury": 3.2712058524857826, "Hepatotoxicity": 24.86453081033385, "Hypercalcaemia": 3.7060830466172767, "Hypertransaminasaemia": 6.225721462704013, "Hypertrophic osteoarthropathy": 473.5437946723953, "Hypokalaemia": 2.495424746309905, "Immunosuppressant drug level increased": 24.32719721298393, "Initial insomnia": 5.681869399632131, "Keratitis fungal": 197.4420336351838, "Liver function test abnormal": 4.9609106261429785, "Liver function test increased": 3.532889541110577, "Liver injury": 14.16604469093819, "Mania": 2.045216658957756, "Mental disorder": 8.13225930813876, "Mucormycosis": 77.5129449144517, "Multiple organ dysfunction syndrome": 4.690752964401965, "Multiple-drug resistance": 4.717739569623929, "Musculoskeletal pain": 2.3127547665720374, "Nephropathy toxic": 3.982611378022996, "Nervous system disorder": 5.956735772289727, "Neurotoxicity": 12.809669691928049, "Off label use": 2.794964345320643, "Pathogen resistance": 20.880268940562104, "Periostitis": 2483.749219642236, "Photodermatosis": 135.0367952619468, "Photophobia": 2.1909299344394944, "Photopsia": 5.974649759405092, "Photosensitivity reaction": 42.82782057483317, "Pneumonia fungal": 16.482551629034095, "Polyneuropathy": 3.3405895687499347, "Posterior reversible encephalopathy syndrome": 3.1651550451971406, "Procalcitonin increased": 28.95326954922581, "Product use in unapproved indication": 2.3142243615843614, "Pseudomonas infection": 4.730976282542804, "Pseudoporphyria": 300.1623556152388, "Pulmonary mass": 4.282430518265219, "Pulmonary mucormycosis": 127.70810980739692, "Renal impairment": 2.7864502866202034, "Respiratory failure": 3.9545349684794857, "Restlessness": 2.12146036490312, "Rhabdomyolysis": 2.861615606029979, "Scedosporium infection": 79.74604688162609, "Septic shock": 3.4798675389559897, "Skin disorder": 3.142508081839344, "Skin lesion": 3.1239454473472112, "Squamous cell carcinoma": 28.479407296174777, "Squamous cell carcinoma of skin": 95.47253107069452, "Systemic candida": 26.521956508645875, "Therapeutic response decreased": 2.779059586604084, "Therapy non-responder": 2.2065954565963803, "Torsade de pointes": 8.95837744414638, "Toxic epidermal necrolysis": 3.840935485416468, "Toxic optic neuropathy": 98.11416738541432, "Transaminases increased": 3.703177262770708, "Treatment failure": 6.608721316496911, "Ventricular extrasystoles": 2.5093890697269887, "Vision blurred": 3.728147057338634, "Visual impairment": 4.336999119729569, "Vitreous floaters": 4.663987563718454, "Xanthopsia": 62.95058771245306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1173.json
index bdcbed27203..f16408797c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1173.json
@@ -1 +1 @@
-{"Lactic acidosis ": 76.28632593236019}
\ No newline at end of file
+{"Akathisia": 18.435545141214945, "Anxiety": 2.948017995130213, "Completed suicide": 11.438855501790384, "Condition aggravated": 4.214090537624172, "Constipation": 4.492642317966971, "Cough": 2.3867835612150863, "Depression": 3.577928223883628, "Drug interaction": 4.033629039292212, "Drug level increased": 12.777375292865074, "Electrocardiogram QT prolonged": 6.587641231327645, "General physical health deterioration": 3.142239720835997, "Hyperhidrosis": 5.7943674053066045, "Hyponatraemia": 5.587325299030235, "Insomnia": 2.0445821955698618, "Irritability": 17.815645187684645, "Joint swelling": 3.38548286213186, "Nausea": 2.4313154618103816, "Overdose": 5.3403495699396695, "Poor quality sleep": 17.93609851102529, "Product use in unapproved indication": 2.926041418364409, "Pruritus": 2.706023298746794, "Serotonin syndrome": 31.178105101448192, "Sexual dysfunction": 41.61842060244262, "Sleep disorder": 4.555933280981491, "Suicidal ideation": 7.8814558191555, "Toxicity to various agents": 2.607143829292662, "Tremor": 2.710047819290026, "Weight increased": 2.176827815022905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1174.json
index 7f631a6b5c6..bef04e97b74 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1174.json
@@ -1 +1 @@
-{"Platelet count decreased ": 33.93475477427325}
\ No newline at end of file
+{"Adverse drug reaction": 4.670840317891651, "Adverse event": 2.106565205965936, "Ageusia": 2.773918290459512, "Alanine aminotransferase increased": 4.2779773441792575, "Amylase increased": 3.026984729139077, "Angiosarcoma": 41.77293056198687, "Angiosarcoma metastatic": 172.01202449436644, "Aspartate aminotransferase increased": 4.301487648370355, "Azotaemia": 2.1059066794008943, "Biliary obstruction": 4.3957767488551465, "Blood albumin decreased": 2.402585991408558, "Blood alkaline phosphatase increased": 2.570788700297784, "Blood bilirubin increased": 7.609380045347937, "Blood creatinine abnormal": 2.4498793095629003, "Blood pressure increased": 3.370858915374193, "Blood sodium decreased": 2.5845965020242723, "Blood thyroid stimulating hormone increased": 8.970993236378499, "Blood urine present": 3.691495286575616, "Bone cancer": 8.150892251551506, "Bone neoplasm": 12.676781439013318, "Brain neoplasm": 6.669036259736003, "Brain neoplasm malignant": 3.735062733615496, "Cancer pain": 3.3998452964372072, "Cardiac dysfunction": 3.0123516808971083, "Cardiac failure": 2.5648993455875715, "Cardiac failure acute": 2.144540732028472, "Cardiotoxicity": 6.360747088098486, "Cataract operation": 3.102775735170774, "Cell death": 3.2183904173091102, "Cholecystectomy": 2.0929049844502297, "Clear cell renal cell carcinoma": 28.76355627670105, "Death": 11.220792342365764, "Decreased appetite": 3.90322581556495, "Dehydration": 2.7438711980589408, "Dialysis": 2.6534595252971527, "Diarrhoea": 3.738750469808292, "Disease progression": 8.687893699150628, "Dry skin": 2.319082014165, "Dry throat": 2.1581839540940706, "Dysgeusia": 2.4895757228936373, "Eating disorder": 2.503788838840824, "Ejection fraction decreased": 9.94933144988663, "Electrolyte imbalance": 2.1646289537605106, "Emergency care examination": 16.49954482242419, "Endometrial stromal sarcoma": 134.39772500777065, "Eyelash discolouration": 56.772157237581325, "Feeding disorder": 2.011874490830634, "Fistula": 3.5527752285482546, "Furuncle": 2.034606580289052, "Gastric haemorrhage": 2.406679903127493, "Gastrointestinal perforation": 7.039805241374208, "Gastrointestinal toxicity": 3.1475600789309914, "Haemoglobin increased": 4.348488230098944, "Haemoptysis": 3.8723978105776578, "Haemorrhage urinary tract": 4.222287702930135, "Haemorrhoidal haemorrhage": 3.0485178520053084, "Hair colour changes": 94.5611094490942, "Hepatic cytolysis": 3.0587464472888755, "Hepatic enzyme abnormal": 2.2391631483056647, "Hepatic enzyme increased": 5.789879291856269, "Hepatic failure": 4.045896300434097, "Hepatic function abnormal": 2.362625784607744, "Hepatic lesion": 2.4030685492749413, "Hepatic neoplasm": 5.737294089541829, "Hepatitis": 2.16004884432652, "Hepatitis toxic": 2.0525038160155784, "Hepatotoxicity": 13.828756504939784, "Hernia repair": 5.59520254407644, "Hip surgery": 7.112025275118933, "Hospice care": 88.34323587239946, "Hospitalisation": 9.68227827480804, "Hydronephrosis": 2.05049387855742, "Hyperbilirubinaemia": 4.75756366774999, "Hyperkeratosis": 4.669224456159599, "Hypertension": 5.0597918172688585, "Hypertensive crisis": 4.912660789291862, "Hypertransaminasaemia": 8.765312647622824, "Hypoalbuminaemia": 2.4101799509869903, "Hypothyroidism": 4.472125644502695, "Ill-defined disorder": 2.2008259465544318, "Impaired healing": 2.3266746471993858, "Internal haemorrhage": 3.032973709693985, "Intestinal perforation": 9.403325405167545, "Intra-abdominal haemorrhage": 3.355343304442659, "Jaundice": 4.473662136858004, "Jaundice cholestatic": 2.8791658437633068, "Large intestine perforation": 5.960899245118172, "Left ventricular dysfunction": 3.168735737032114, "Leiomyosarcoma metastatic": 128.5271986993595, "Limb operation": 5.278391815847565, "Lipase increased": 2.7873366373119564, "Liver disorder": 2.061150486334104, "Liver function test abnormal": 3.0682278115770854, "Liver function test increased": 7.917242524667291, "Living in residential institution": 21.713913861893857, "Lung abscess": 4.449351553035297, "Lung neoplasm": 9.266638596664054, "Lung operation": 10.66369760815222, "Lymphadenopathy mediastinal": 3.620643576250691, "Madarosis": 3.754044316291969, "Malignant connective tissue neoplasm": 1165.1732247638752, "Malignant neoplasm progression": 13.28520716586008, "Metastases to adrenals": 11.730257387447825, "Metastases to bone": 6.969653136969008, "Metastases to central nervous system": 13.856136011628116, "Metastases to kidney": 25.069343267375142, "Metastases to liver": 6.395487341774149, "Metastases to lung": 21.48019136910384, "Metastases to lymph nodes": 6.438153289411878, "Metastases to pancreas": 22.25127026025585, "Metastases to peritoneum": 3.611108865173556, "Metastases to skin": 7.616249199893995, "Metastases to spine": 9.81058885925851, "Metastasis": 17.38652411379557, "Metastatic neoplasm": 11.82295108728882, "Metastatic renal cell carcinoma": 26.658796092450817, "Mucosal inflammation": 5.686589905217481, "Neoplasm": 5.259648947893268, "Neoplasm malignant": 4.357770247904095, "Nephrectomy": 8.576910030566427, "Nephrotic syndrome": 4.746626224643749, "Oral pain": 2.1067785853905527, "Orthopnoea": 3.537026681557241, "Osteonecrosis of jaw": 2.294451649629253, "Palliative care": 25.405691378746152, "Palmar-plantar erythrodysaesthesia syndrome": 6.7670847852677065, "Pancreatitis": 2.1518282849842776, "Pigmentation disorder": 3.5697638270200724, "Pleural effusion": 3.795238634818634, "Pneumothorax": 21.79921209366731, "Pneumothorax spontaneous": 13.39582429963201, "Posterior reversible encephalopathy syndrome": 10.417503973718985, "Proctalgia": 3.1426266372805896, "Product use in unapproved indication": 2.9432013794792, "Protein urine present": 2.477851817494573, "Proteinuria": 6.281423010616346, "Pulmonary haemorrhage": 2.8514412085888394, "Pulmonary mass": 4.092971664586369, "Pulmonary thrombosis": 2.405848850274854, "Pyoderma gangrenosum": 4.510479234840365, "Radiotherapy": 22.116721311726277, "Rectal abscess": 12.622624450274008, "Recurrent cancer": 7.1166075887003535, "Red cell distribution width increased": 2.5339163914717275, "Regurgitation": 2.9108483682325774, "Rehabilitation therapy": 11.638223904488884, "Renal cancer": 12.652953125544244, "Renal cancer metastatic": 55.86992310414446, "Renal cancer recurrent": 67.3760101099884, "Renal cancer stage IV": 28.274708536600084, "Renal cell carcinoma": 17.74960585889205, "Renal cell carcinoma stage IV": 72.01231778799871, "Renal haemorrhage": 7.647369860480371, "Renal neoplasm": 10.66152154585468, "Renal surgery": 65.51764541373763, "Retinal detachment": 4.794891790434898, "Retinal tear": 9.127293484818644, "Rhabdomyosarcoma": 48.498195511699386, "Sarcoma": 77.62989729937053, "Sarcoma metastatic": 281.6086071350395, "Second primary malignancy": 4.516309952548652, "Skin depigmentation": 6.857300794189839, "Skin discolouration": 3.3253518754701754, "Skin toxicity": 4.245703711273653, "Skin ulcer": 2.5809980532366565, "Soft tissue sarcoma": 317.1814984074679, "Stomatitis": 3.571288332668986, "Surgery": 3.3649221351965504, "Taste disorder": 5.687004959638173, "Terminal state": 5.308851107708662, "Thyroid function test abnormal": 4.674602976227767, "Tongue discomfort": 2.6302390230282424, "Transaminases increased": 5.283069604041435, "Transfusion": 2.1073581788693665, "Tumour excision": 45.44968984877484, "Tumour haemorrhage": 9.312143106967412, "Tumour necrosis": 12.057308322147298, "Tumour pain": 30.132106336247368, "Urinary bladder haemorrhage": 4.879666110347417, "Uterine leiomyosarcoma": 79.10750355765147, "Vena cava thrombosis": 8.453369409875581, "Ventricular dysfunction": 5.371430465570555, "Vitreous detachment": 3.008657789062193, "Weight decreased": 2.862116427183357, "Yellow skin": 3.808115026102385}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1175.json
index fa7a7bb214c..98416661146 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1175.json
@@ -1 +1 @@
-{"Anaemia ": 9.07720204718618, "Bedridden ": 2.886133874536462, "Blood alkaline phosphatase decreased ": 168.24900498148753, "Blood alkaline phosphatase increased ": 8.514820350451952, "Blood lactate dehydrogenase increased ": 2.1035855469421563, "Blood test abnormal ": 11.552122865732096, "Bone marrow failure ": 11.195563972528, "Bone marrow infiltration ": 191.6961859485745, "Bone pain ": 11.592977078852812, "Cancer pain ": 58.63330464800885, "Cytopenia ": 3.0320461890814507, "Death ": 4.442159241223041, "Decreased appetite ": 2.66011209923953, "Disease progression ": 11.416595869811308, "Disseminated intravascular coagulation ": 3.432885531902864, "Femur fracture ": 3.916114511767302, "Fracture ": 2.385889912485718, "Full blood count abnormal ": 6.235813645803122, "General physical health deterioration ": 19.89063277251192, "Haematotoxicity ": 21.636823630609022, "Haemoglobin abnormal ": 11.868087732710553, "Haemoglobin decreased ": 13.41192386233636, "Hip fracture ": 2.1735032765630296, "Hormone-refractory prostate cancer ": 2531.64539760757, "Hospitalisation ": 2.316762870105822, "Hydronephrosis ": 8.682038977987448, "Laboratory test abnormal ": 5.109347993959273, "Leukopenia ": 3.309170650389392, "Malignant neoplasm progression ": 3.833058014482327, "Metastases to bone ": 106.22421418528654, "Metastases to bone marrow ": 112.18539757329346, "Metastases to central nervous system ": 13.794139072933582, "Metastases to liver ": 46.14883717192665, "Metastases to lung ": 20.97677760725499, "Metastases to lymph nodes ": 39.55039531435719, "Metastases to meninges ": 26.34510649230741, "Metastases to spine ": 72.41624308179424, "Metastasis ": 56.17192846609832, "Musculoskeletal chest pain ": 2.9521658499840675, "Myelosuppression ": 6.721688788318357, "Neutropenia ": 2.575306574065629, "Neutrophil count decreased ": 4.347183286645701, "No adverse event ": 9.26591997490989, "Osteonecrosis of jaw ": 41.595890843858456, "Pancytopenia ": 9.63964719827858, "Pathological fracture ": 42.76582127475856, "Pelvic pain ": 4.167684597142023, "Physical deconditioning ": 6.917627610377852, "Platelet count decreased ": 10.10074188601193, "Pre-existing condition improved ": 25.73337451081017, "Prostate cancer ": 41.50683373793359, "Prostate cancer metastatic ": 274.5854082570385, "Prostate cancer stage IV ": 669.6419292504548, "Prostatic specific antigen increased ": 246.02777608228257, "Red blood cell count decreased ": 3.6771648295936767, "Sepsis ": 2.018308417063776, "Spinal compression fracture ": 15.676576970586376, "Spinal cord compression ": 125.827529060048, "Spinal pain ": 5.5720946801880205, "Subdural haematoma ": 3.644857750081609, "Thrombocytopenia ": 6.969837955676304, "Transfusion ": 5.448950213336653, "Weight decreased ": 2.23881337343016, "White blood cell count decreased ": 3.423085248372752}
\ No newline at end of file
+{"Acute myeloid leukaemia": 24.820892408198187, "Acute pulmonary oedema": 42.04640313285206, "Bone marrow failure": 72.6453326643622, "Cardiac failure": 3.779235692704942, "Cellulitis": 9.518420207280547, "Congenital aplasia": 129.9025222046795, "Cytopenia": 33.660536962413545, "Disease progression": 4.415020525486679, "Ejection fraction decreased": 28.066634161035328, "Febrile neutropenia": 55.21249773350638, "Infection": 3.754817677984384, "Neutropenia": 8.10225015103477, "Neutropenic sepsis": 138.48004694764285, "Pancytopenia": 7.139146307915707, "Pneumonia": 3.997308280556528, "Pneumonia fungal": 91.18708181728309, "Rash": 2.7462227494887474, "Rash maculo-papular": 10.775519792920134, "Sepsis": 14.025509133946256, "Septic shock": 10.34632368369127, "Thrombocytopenia": 5.5322410239299}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1176.json
index a939ddf0f46..d42bf3664d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1176.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 4.235924985411844, "Allergy to animal ": 5.336252706063613, "Anaphylactic reaction ": 12.053879170124592, "Anaphylactoid reaction ": 3.496956817012715, "Angioedema ": 4.969808796998703, "Antinuclear antibody positive ": 2.757847378933025, "Aphonia ": 3.0061926110009853, "Asthma ": 17.399260804877425, "Asthmatic crisis ": 15.189563851014636, "Atypical pneumonia ": 3.3041485295367634, "Blood immunoglobulin E abnormal ": 110.40345288820612, "Blood immunoglobulin E decreased ": 73.89204220973382, "Blood immunoglobulin E increased ": 51.41391733544492, "Blood immunoglobulin G decreased ": 4.002424426005726, "Blood pressure diastolic decreased ": 2.381075546271854, "Blood pressure systolic increased ": 2.830253663699947, "Body temperature decreased ": 2.679584000995417, "Breast cancer ": 3.7785167452857, "Breast conserving surgery ": 6.142662017505936, "Breast mass ": 3.008872779811941, "Breast neoplasm ": 7.519044519746774, "Breath sounds abnormal ": 5.307364265968516, "Bronchial secretion retention ": 3.392692037356375, "Bronchiectasis ": 2.431348778599655, "Bronchitis ": 5.29452505358948, "Bronchitis chronic ": 3.5212798120886037, "Bronchopulmonary aspergillosis allergic ": 7.645767157499886, "Bronchospasm ": 6.079094022198634, "Chest discomfort ": 4.4194928818101, "Choking ": 2.697133503589303, "Choking sensation ": 2.782763696931359, "Chronic obstructive pulmonary disease ": 2.6170288884405863, "Chronic spontaneous urticaria ": 90.44937830054408, "Circumoral oedema ": 7.747470057477846, "Colon cancer ": 2.895647900133583, "Computerised tomogram abnormal ": 5.262822873659927, "Concomitant disease aggravated ": 3.315331822590602, "Coronavirus infection ": 2.790707510922037, "Cough ": 3.3632653157018115, "Cystic fibrosis ": 3.899683002506681, "Dermatitis atopic ": 6.10030137690918, "Diffuse alopecia ": 2.6869496960160277, "Dysphonia ": 2.6851119115028546, "Dyspnoea ": 2.9302373032031803, "Dyspnoea exertional ": 2.1145989537354444, "Ear infection ": 3.040112373374012, "Ear swelling ": 2.5926258146026218, "Enlarged uvula ": 6.504797389452493, "Eosinophil count increased ": 5.476101458511203, "Eosinophilic granulomatosis with polyangiitis ": 16.741397252534668, "Eosinophilic oesophagitis ": 6.299321516974139, "Eye oedema ": 3.103130538697072, "Eye pruritus ": 4.486953457092273, "Eye swelling ": 2.607784550082871, "FEV1/FVC ratio decreased ": 74.0900143252954, "Flushing ": 3.7167230737031383, "Food allergy ": 4.486514102666203, "Forced expiratory volume decreased ": 29.310949396213665, "Frustration tolerance decreased ": 3.0572908959121645, "Gastroenteritis viral ": 2.138554759247791, "Heart rate increased ": 2.371493000048711, "Human anti-human antibody test ": 156.16425587215184, "Hypersensitivity ": 3.334261641298798, "Hyperventilation ": 4.153475508116762, "Hypoventilation ": 9.901946952078251, "Idiopathic urticaria ": 24.82710464781455, "Incorrect route of product administration ": 3.1794267996872017, "Increased upper airway secretion ": 2.716521190795712, "Infection parasitic ": 14.404427049283964, "Infectious mononucleosis ": 3.316866878219124, "Injection site oedema ": 2.788245982201012, "Injection site rash ": 2.0114252623578666, "Injection site reaction ": 2.1324345902204658, "Injection site urticaria ": 5.925211167070972, "Intraductal proliferative breast lesion ": 5.399930913896246, "Invasive ductal breast carcinoma ": 2.794409469416894, "Lacrimation increased ": 2.6458595144824386, "Laryngeal oedema ": 3.921325090860384, "Laryngitis ": 2.761500365448212, "Ligament rupture ": 3.2013016684220634, "Ligament sprain ": 3.8122382356983993, "Lip swelling ": 4.252408121442034, "Lower respiratory tract infection ": 2.619215877332144, "Lung adenocarcinoma ": 5.475644854129506, "Lung disorder ": 2.1207053982336586, "Lung neoplasm malignant ": 2.021281790340965, "Lymphoma ": 3.184390382058309, "Malignant melanoma ": 2.1604329481759623, "Mast cell activation syndrome ": 8.266462843097395, "Mastectomy ": 4.165933766731786, "Maternal exposure during pregnancy ": 3.8061345723664624, "Middle insomnia ": 3.682727916880797, "Mouth swelling ": 2.278699143611436, "Nasal congestion ": 4.818888881202088, "Nasal polyps ": 5.865389581311857, "Nasopharyngitis ": 3.508971402582956, "Needle issue ": 6.233384332184372, "Neutrophil count increased ": 2.5332110599457502, "Normal newborn ": 14.595419058219372, "Obstructive airways disorder ": 5.655817256685253, "Oesophageal spasm ": 5.055931464545518, "Oropharyngeal pain ": 2.134960302884575, "Oropharyngeal swelling ": 5.334275528398657, "Paranasal sinus discomfort ": 2.3568381766486555, "Peak expiratory flow rate decreased ": 39.524262476685344, "Pharyngeal disorder ": 4.549457264915034, "Pharyngeal oedema ": 2.791571589983282, "Pharyngeal swelling ": 5.751740422515013, "Pharyngitis ": 2.452025554320373, "Pharyngitis streptococcal ": 2.425971990554596, "Pigmentation disorder ": 2.2232093522323515, "Pleural rub ": 121.40023571606756, "Pneumonia ": 2.557268297172824, "Polyp ": 2.047137667216888, "Postoperative wound infection ": 2.118523083237267, "Product supply issue ": 2.5835795722786825, "Productive cough ": 7.555071575066395, "Pruritus ": 2.642180799900074, "Pulmonary congestion ": 6.035381876711719, "Pulmonary function test decreased ": 11.295100128559682, "Pulmonary mass ": 3.007078089172426, "Rales ": 2.939297022574942, "Respiratory disorder ": 3.409257585453896, "Respiratory distress ": 2.2562026105387103, "Respiratory rate increased ": 5.157380116918331, "Respiratory tract congestion ": 11.02649695039315, "Respiratory tract infection ": 4.308261556089283, "Rhinitis ": 2.456566342968939, "Rhinorrhoea ": 2.344692654500089, "Rhonchi ": 9.19097870107115, "Rubber sensitivity ": 7.043352307243448, "Scratch ": 4.281244513369621, "Seasonal allergy ": 4.112645436382335, "Secretion discharge ": 4.859287380261092, "Sensation of foreign body ": 3.1418626587713843, "Sensitivity to weather change ": 6.485839434529864, "Serum sickness ": 25.031819764707457, "Serum sickness-like reaction ": 10.77172523023931, "Sinus congestion ": 7.812264648315513, "Sinus disorder ": 4.006661407798301, "Sinus operation ": 7.436710230346999, "Sinusitis ": 4.743780779947715, "Skin infection ": 3.342033417534267, "Skin lesion ": 2.280642946835563, "Skin oedema ": 5.874135795690657, "Skin plaque ": 4.687672818951868, "Skin sensitisation ": 7.046871761810538, "Skin swelling ": 3.0656877192478333, "Sneezing ": 4.156687875883475, "Spirometry abnormal ": 9.540569282855714, "Sputum discoloured ": 16.468371354490174, "Sputum increased ": 2.3035979674062435, "Sputum retention ": 4.97966480795533, "Stillbirth ": 2.539588048741906, "Streptococcal infection ": 2.333086403524534, "Stress ": 2.065344037271125, "Stridor ": 5.414520676846805, "Suffocation feeling ": 2.384472788429843, "Swelling face ": 3.153603937995646, "Swelling of eyelid ": 2.02944239045929, "Swollen tongue ": 3.8450131494927584, "Symptom recurrence ": 3.3462164605735776, "Syringe issue ": 4.5638630696758895, "Temperature intolerance ": 2.987774435861719, "Throat clearing ": 7.0406736085255845, "Throat irritation ": 4.394188159004771, "Throat tightness ": 7.456707910602027, "Thyroid cancer ": 2.2299419951494794, "Tongue disorder ": 2.40085035171356, "Type I hypersensitivity ": 4.032933074165289, "Type III immune complex mediated reaction ": 9.123314363409628, "Upper airway obstruction ": 19.60295950321052, "Upper limb fracture ": 2.070160168182349, "Upper respiratory tract congestion ": 4.333657040116179, "Upper respiratory tract infection ": 3.282196683747181, "Upper-airway cough syndrome ": 4.361711039263777, "Urticaria ": 6.430045808586802, "Urticaria chronic ": 3.624366755925291, "Urticarial vasculitis ": 13.52977861737449, "Viral infection ": 4.297590070120743, "Weight increased ": 2.3426226883093952, "Wheezing ": 12.40408352587772, "White blood cell count increased ": 2.229889542836527}
\ No newline at end of file
+{"Aggression": 8.930435894476338, "Anxiety": 3.897745817976608, "Depression": 3.248671775367829, "Drug interaction": 3.393281379710399, "Insomnia": 5.2608246701273504, "Irritability": 8.507436424297984, "Nightmare": 13.11133970060878, "Off label use": 2.919250018059209, "Suicidal ideation": 7.910600710596054, "Weight increased": 3.1680145728063605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1177.json
index aa4f1883b58..6a185d4fdca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1177.json
@@ -1 +1 @@
-{"Amnesia ": 2.4786911840725074, "Aortic dissection ": 2.5107483294547484, "Asthenia ": 2.446456551696473, "Back pain ": 2.982876412686557, "Balance disorder ": 2.409506461859013, "Bedridden ": 2.6162967607047487, "Bladder disorder ": 2.411278278563966, "Blood urine present ": 10.157948898610009, "Bone cancer ": 19.7788821453022, "Bone lesion ": 3.5066149558470143, "Bone pain ": 3.758905539395671, "Cancer pain ": 19.53471988627772, "Cerebrovascular accident ": 2.005672820550863, "Choking ": 3.0075903289379786, "Cognitive disorder ": 3.513692213241961, "Compression fracture ": 4.798983212938757, "Constipation ": 3.232921755092056, "Cystitis ": 2.7696308003593666, "Death ": 11.995366495415595, "Decreased appetite ": 5.038737498830942, "Decreased interest ": 3.500845114834425, "Dehydration ": 2.105359393334997, "Dementia ": 4.215567406105599, "Dementia Alzheimer's type ": 2.241627140416161, "Dysphagia ": 6.667219705365622, "Dysstasia ": 2.0243222908186453, "Eating disorder ": 2.564511658533738, "Faeces hard ": 2.7048557744654835, "Failure to thrive ": 4.361504152245531, "Fall ": 4.227070434871148, "Feeding disorder ": 2.511557472977726, "Femur fracture ": 2.133065772637197, "Foreign body in throat ": 23.56750391630196, "Fracture ": 2.0313533656356904, "Full blood count decreased ": 3.4862464490880787, "Gait disturbance ": 2.0612346267840835, "Gait inability ": 2.4856700675003744, "General physical health deterioration ": 2.547642216100543, "Gynaecomastia ": 2.51981684479072, "Haematuria ": 2.0918382320871345, "Haemorrhage urinary tract ": 7.8092025705464865, "Head injury ": 2.023987785892876, "Hip fracture ": 3.95226414268878, "Hormone-refractory prostate cancer ": 10.83061766443097, "Hospice care ": 9.104758627401148, "Hospitalisation ": 7.95369580394521, "Hot flush ": 9.873220279739709, "Hydronephrosis ": 3.5142821980481207, "Hypersomnia ": 3.345165253333059, "Hypogeusia ": 2.106872608271572, "Illness ": 2.0692474149456146, "Incontinence ": 2.3260090743721022, "Intentional dose omission ": 11.041481994955625, "Intentional underdose ": 17.542703145611828, "International normalised ratio decreased ": 2.6843084356349656, "Kidney infection ": 2.464779679548623, "Malignant neoplasm progression ": 33.76219057946895, "Memory impairment ": 3.0024892426353595, "Metastases to bone ": 9.678539324149195, "Metastases to central nervous system ": 2.042302060067424, "Metastases to spine ": 5.766791176801762, "Metastasis ": 6.664261700612534, "Metastatic neoplasm ": 2.5766044654416627, "Muscular weakness ": 2.495394483175778, "Neoplasm ": 2.78309094623456, "Nocturia ": 4.564941828923853, "Oncologic complication ": 17.07118321948716, "Pathological fracture ": 2.305351023381109, "Performance status decreased ": 2.2526829574376426, "Peripheral swelling ": 2.492510051591361, "Physical deconditioning ": 2.315673831297754, "Pneumonia aspiration ": 2.079228066426385, "Pollakiuria ": 3.2310860258787715, "Posterior reversible encephalopathy syndrome ": 5.153549072430196, "Prescribed underdose ": 15.400983405917302, "Product availability issue ": 2.802395357476865, "Product dose omission issue ": 3.5060257632232683, "Product physical issue ": 2.810342116830472, "Product size issue ": 157.7860447798756, "Product use complaint ": 14.154089949971391, "Prostate cancer ": 10.816870647420302, "Prostate cancer metastatic ": 23.287040880013382, "Prostate cancer recurrent ": 16.770769596990146, "Prostatic specific antigen abnormal ": 105.7858051350146, "Prostatic specific antigen increased ": 236.49024028387117, "Regurgitation ": 2.222294789879967, "Restless legs syndrome ": 5.586587972308941, "Rib fracture ": 2.897442286644785, "Seizure ": 2.361213584828544, "Shoulder fracture ": 3.944255454997076, "Sinus disorder ": 2.6194753839403355, "Spinal compression fracture ": 3.104267528445399, "Spinal cord compression ": 10.221922409564849, "Spinal cord neoplasm ": 16.244264038495704, "Spinal operation ": 2.4496477590400207, "Stent placement ": 4.0106960763241775, "Taste disorder ": 3.697972778776074, "Terminal state ": 13.890725342976491, "Throat cancer ": 2.4759666002173493, "Tooth extraction ": 2.065093327589126, "Treatment noncompliance ": 5.955133806365104, "Underdose ": 33.0552666161666, "Upper limb fracture ": 3.156395475389211, "Ureteric obstruction ": 7.205096110626176, "Urinary bladder haemorrhage ": 6.414623725004774, "Urinary incontinence ": 2.1573132057832267, "Urinary tract disorder ": 2.7969391403258377, "Urinary tract infection ": 3.265964861724747, "Urinary tract obstruction ": 5.677076881147115, "Vascular graft ": 4.104576591490448, "Walking aid user ": 2.140420282989459, "Walking disability ": 2.150272596352453, "Weight decreased ": 3.365319771544744, "Wrong technique in product usage process ": 2.234417457183803}
\ No newline at end of file
+{"Alanine aminotransferase increased": 5.693584396010497, "Aspartate aminotransferase increased": 5.088305198231373, "Blood albumin decreased": 6.441289094879018, "Blood alkaline phosphatase increased": 2.523291377501947, "Blood bilirubin increased": 2.1730741132294216, "Blood potassium increased": 2.00065086666733, "Bradycardia": 7.817355391280761, "Cardiac failure": 2.795190824983952, "Constipation": 4.290930352864862, "Death": 7.98864785379812, "Decreased appetite": 2.234628177644302, "Disease progression": 29.897350381351128, "Drug-induced liver injury": 2.759578763855235, "Dysgeusia": 3.847660958208119, "Dyspepsia": 2.206614579092871, "Dysphagia": 2.721957920702261, "Eating disorder": 2.673495988593454, "Electrocardiogram QT prolonged": 7.204074579501508, "Feeding disorder": 3.2814206874155505, "Fluid retention": 2.656702451330084, "Gastrooesophageal reflux disease": 2.146538766138853, "Generalised oedema": 4.499413095760138, "Haemoptysis": 2.580986328000739, "Heart rate decreased": 3.912367495704781, "Hepatic enzyme increased": 3.6045794617790343, "Hepatic failure": 3.4069040832345747, "Hepatic function abnormal": 5.255674747529746, "Hepatitis": 2.1524371245495257, "Hepatotoxicity": 10.712764797639675, "Hypertransaminasaemia": 5.77310332854318, "Interstitial lung disease": 5.420917694929534, "Liver disorder": 2.6982119486132814, "Liver function test abnormal": 2.4478917049008104, "Liver function test increased": 6.77451798307465, "Liver injury": 2.6201608926682707, "Lung adenocarcinoma": 44.00791185422814, "Lung adenocarcinoma stage IV": 85.52356478007565, "Lung cancer metastatic": 23.50581052782383, "Lung neoplasm malignant": 65.06347904480481, "Neoplasm malignant": 6.995653352001748, "Neoplasm progression": 55.10796811966359, "Neutropenia": 2.0998233484555104, "Non-small cell lung cancer": 94.28499747426464, "Non-small cell lung cancer metastatic": 149.7730456624511, "Odynophagia": 3.7569855983701848, "Oedema": 6.1516870180396825, "Oedema peripheral": 7.280199065753124, "Oesophageal candidiasis": 6.359841939999329, "Oesophageal pain": 8.37860289029666, "Oesophageal ulcer": 39.54303907059105, "Oesophagitis": 16.014376240973323, "Pericardial effusion": 6.813298819426448, "Peripheral swelling": 2.2426008614593327, "Photopsia": 29.1764804164103, "Pleural effusion": 8.048869739736423, "Pneumonia": 4.06922730623706, "Pneumonitis": 11.01864522069129, "Product use in unapproved indication": 4.037141131919243, "Protein total decreased": 9.520158694719164, "Pulmonary embolism": 3.251779859054128, "Pulmonary oedema": 4.487361241282023, "Pulmonary thrombosis": 4.601415207929729, "Renal abscess": 63.46430004001686, "Renal cyst": 16.689673689554763, "Renal impairment": 3.20733883051391, "Respiratory failure": 4.1897008015920125, "Second primary malignancy": 10.644337466105158, "Sinus bradycardia": 7.728385090754297, "Taste disorder": 6.141023578679089, "Thrombosis": 2.7876026998942804, "Transaminases increased": 4.761395478542955, "Vasogenic cerebral oedema": 64.93326519523193, "Visual impairment": 5.382014105059722, "Vitreous floaters": 6.663853560790042, "Vomiting": 2.2026802906884155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1178.json
index 7ea6f81fce6..666c433792c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1178.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 2.562222455144273, "Abnormal dreams ": 8.91516435096831, "Abnormal sleep-related event ": 109.88972220291755, "Adverse drug reaction ": 2.341548170670347, "Agitation ": 4.6827162084615965, "Amnesia ": 2.1995343898763675, "Anger ": 2.2570229130518658, "Anxiety ": 4.678931396658194, "Apnoea ": 3.7164870615315473, "Arthritis ": 2.431628755455323, "Back disorder ": 8.387743550887034, "Bipolar disorder ": 6.017577541938056, "Blood potassium decreased ": 5.348963562480917, "Blood pressure increased ": 2.8783708844042546, "Blood sodium decreased ": 2.5091136657630977, "Brain fog ": 2.345878159167349, "Breath holding ": 93.9842839999692, "Bronchitis ": 2.745425383566882, "Cataplexy ": 484.90612104083385, "Coma ": 2.4178254001898605, "Conduction disorder ": 21.35360636598173, "Delusion ": 5.735166811737682, "Depressed level of consciousness ": 5.4372118707299295, "Depression ": 5.542094687141068, "Drug abuse ": 2.331073061463816, "Drug hypersensitivity ": 3.960839652326516, "Drug screen positive ": 26.8361402461562, "Drug withdrawal syndrome ": 2.070564829784533, "Dry eye ": 2.591655121507472, "Electrolyte imbalance ": 7.033362324740189, "Enuresis ": 55.01823440148234, "Eye haemorrhage ": 3.0555226287267105, "Fall ": 2.997594295639119, "Feeling abnormal ": 4.958327086551993, "Feeling drunk ": 9.496381190061712, "Feeling jittery ": 23.63650974650078, "Fibromyalgia ": 6.786034529679121, "Foot fracture ": 2.2089337026026463, "Gastritis ": 2.142776586231483, "Hallucination ": 3.638520376701773, "Hangover ": 15.869527954881004, "Head injury ": 2.781333811644462, "Heart rate decreased ": 2.018743809974245, "Hunger ": 7.412476807352304, "Hypertension ": 2.9746574395676864, "Initial insomnia ": 12.422226735229687, "Insomnia ": 2.416921029873992, "Intentional product misuse ": 3.5747610497699687, "Intentional product use issue ": 3.297483072452432, "Intervertebral disc degeneration ": 5.197283268681771, "Intervertebral disc protrusion ": 7.969155623542485, "Irritability ": 4.259291997258726, "Joint dislocation ": 5.122601361281031, "Joint injury ": 4.204518378548572, "Lethargy ": 3.511171568626322, "Limb injury ": 3.89101592731847, "Mania ": 3.17662604767393, "Memory impairment ": 3.484801502040036, "Migraine ": 2.75245547697651, "Mood altered ": 2.380997367637278, "Muscle tightness ": 6.2617087744399615, "Narcolepsy ": 49.08378363190105, "Nephrolithiasis ": 3.2683663559732485, "Nervousness ": 5.17106940957871, "Neuralgia ": 2.436432241168069, "Nightmare ": 2.909004273096369, "Obsessive-compulsive disorder ": 5.763962290003075, "Obstructive sleep apnoea syndrome ": 22.398941260294063, "Overdose ": 2.421502865789863, "Panic attack ": 5.907251742015056, "Paranoia ": 9.683113198735764, "Parasomnia ": 102.17006879388096, "Pollakiuria ": 3.122479395364816, "Poor quality sleep ": 3.1288373834274723, "Pre-existing condition improved ": 18.91428706978631, "Psychomotor hyperactivity ": 3.042851549867131, "Psychotic disorder ": 5.2358790165350255, "Respiratory depression ": 8.265027129324123, "Restless legs syndrome ": 4.735675121532666, "Road traffic accident ": 4.025683305634043, "Sedation ": 4.006303483220632, "Sinusitis ": 3.5627476951660317, "Skin laceration ": 4.640391406402893, "Sleep apnoea syndrome ": 24.40824121628004, "Sleep paralysis ": 44.54866766080696, "Sleep terror ": 16.091386182075908, "Sleep-related eating disorder ": 401.28825518090326, "Snoring ": 19.3089756108348, "Somnambulism ": 52.219381996692576, "Somnolence ": 4.256591348738217, "Stress ": 6.489671831261996, "Suicidal ideation ": 5.22832178953762, "Suicide attempt ": 5.339331875882588, "Therapeutic response unexpected ": 13.325031925648712, "Thinking abnormal ": 3.0482230245428847, "Tooth disorder ": 5.840999857338879, "Tremor ": 2.7968803022383324, "Unevaluable event ": 17.527563031262044, "Weight decreased ": 5.238743742022834, "Weight increased ": 2.19969086193454, "Wrong technique in product usage process ": 2.882598558017876}
\ No newline at end of file
+{"Abdominal wall haematoma": 19.39152434148882, "Abnormal loss of weight": 8.345556497234348, "Abnormal uterine bleeding": 61.50583073755554, "Activated partial thromboplastin time prolonged": 12.21657314395192, "Acute kidney injury": 5.271679558945085, "Acute respiratory failure": 3.711039483353092, "Anaemia": 2.545106159491493, "Anticoagulation drug level above therapeutic": 13.327564404483804, "Atrial fibrillation": 4.146845533062671, "Blood loss anaemia": 39.12333146256927, "Blood urine present": 12.087292543389566, "Cardiac failure congestive": 2.1759467543021063, "Cerebellar haemorrhage": 10.04960361465968, "Cerebral haematoma": 13.490481591423986, "Cerebral haemorrhage": 10.43877444302644, "Cerebral infarction": 2.1204028019335257, "Cerebral thrombosis": 8.356462959123247, "Cholestasis": 2.386691429780636, "Chronic obstructive pulmonary disease": 2.593022001589105, "Coagulopathy": 13.740802257186036, "Contusion": 2.970303125603756, "Deep vein thrombosis": 7.124183162691977, "Dermatitis bullous": 2.135694196566929, "Diarrhoea haemorrhagic": 2.3036907577629604, "Diverticulum intestinal haemorrhagic": 52.14436765853645, "Drug interaction": 6.378505066288155, "Duodenal ulcer haemorrhage": 14.474002180915386, "Ear haemorrhage": 12.908940136082927, "Ecchymosis": 4.354286915935052, "Embolic stroke": 9.72745224184898, "Emphysema": 2.5593348205418978, "Epistaxis": 10.310139729868803, "Eye haemorrhage": 2.640729038651833, "Faeces discoloured": 2.1264585238691427, "Fall": 2.235868371022451, "Gastric haemorrhage": 3.496552743041361, "Gastric ulcer": 5.426766014721341, "Gastric ulcer haemorrhage": 17.499262302920044, "Gastritis haemorrhagic": 11.77387208209341, "Gastrointestinal haemorrhage": 35.33280087468717, "Gastrointestinal polyp haemorrhage": 50.88177702095466, "Gastrointestinal vascular malformation haemorrhagic": 113.62537844237836, "Gingival bleeding": 13.3193976871396, "Haemarthrosis": 13.211687972133172, "Haematemesis": 7.784190337045868, "Haematochezia": 4.9465574242523065, "Haematoma": 9.002013364122046, "Haematoma muscle": 16.142705403003053, "Haematuria": 19.47667888848008, "Haemoglobin decreased": 3.1925131517531797, "Haemoptysis": 11.070736938417404, "Haemorrhage": 8.218444847100072, "Haemorrhage intracranial": 10.166937592885102, "Haemorrhage subcutaneous": 5.863796995998415, "Haemorrhage urinary tract": 7.389123279562001, "Haemorrhagic arteriovenous malformation": 245.64703109920376, "Haemorrhagic diathesis": 8.985751905708424, "Haemorrhagic stroke": 23.98177836364397, "Haemorrhagic transformation stroke": 31.698128636877968, "Haemorrhoidal haemorrhage": 45.96255273256549, "Haemothorax": 20.66909927323392, "Hemiplegia": 6.492058862692474, "Hepatitis cholestatic": 2.341395234823331, "Hypervolaemia": 3.858669192579097, "Hypovolaemic shock": 18.02064426702114, "Incorrect dose administered": 2.4655129228295745, "Increased tendency to bruise": 9.307048360865997, "Internal haemorrhage": 91.2080853710169, "International normalised ratio increased": 9.560471500323258, "Intestinal haemorrhage": 4.10846404499321, "Intra-abdominal haematoma": 7.838536786592517, "Iron deficiency anaemia": 8.012358241119333, "Ischaemic stroke": 8.512942910284098, "Labelled drug-drug interaction medication error": 11.869543284749875, "Lactic acidosis": 2.555879522454513, "Large intestinal haemorrhage": 15.773913364199675, "Lower gastrointestinal haemorrhage": 65.06573702400466, "Melaena": 9.830170024322836, "Mouth haemorrhage": 10.192896405835326, "Muscle haemorrhage": 9.088419294248208, "Occult blood positive": 9.944278996874278, "Pemphigoid": 2.415875461209798, "Peptic ulcer haemorrhage": 20.91946217650754, "Pericardial haemorrhage": 24.25815085531806, "Peripheral artery occlusion": 11.790499690839017, "Post procedural haemorrhage": 15.694598329229065, "Prescribed underdose": 4.39168114912845, "Procedural haemorrhage": 17.40844868134598, "Product prescribing issue": 5.062092678220416, "Prothrombin time prolonged": 12.939366073535084, "Pulmonary alveolar haemorrhage": 9.978223399768538, "Pulmonary embolism": 4.876961422887843, "Pulmonary haemorrhage": 8.910864175538967, "Pulmonary thrombosis": 5.562793845876686, "Purpura": 3.444562522533756, "Rectal haemorrhage": 19.42164022474268, "Renal haemorrhage": 49.003750226858166, "Respiratory failure": 2.8779032054692766, "Retroperitoneal haematoma": 10.66453769730496, "Retroperitoneal haemorrhage": 13.873805144048994, "Right ventricular failure": 3.661995248119708, "Shock haemorrhagic": 20.1780348326518, "Sinus bradycardia": 2.7091539301764347, "Skin haemorrhage": 8.549732001107788, "Subarachnoid haemorrhage": 8.105009312477103, "Subcutaneous haematoma": 12.316947880461283, "Subdural haematoma": 12.921724845679815, "Subdural haemorrhage": 8.478360325915741, "Thalamus haemorrhage": 12.366845981219775, "Thrombosis": 3.617483521030592, "Treatment noncompliance": 2.304010127136201, "Ulcer haemorrhage": 3.3207938069000185, "Upper gastrointestinal haemorrhage": 38.23679155587341, "Uterine haemorrhage": 11.54904791316683, "Vaginal haemorrhage": 8.649417851682612, "Wound haemorrhage": 13.521369733008749}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1179.json
index c5fea50027d..64fb46aba1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1179.json
@@ -1 +1 @@
-{"Adrenal disorder ": 21.74454274747636, "Adrenal insufficiency ": 20.863380297241548, "Adrenocortical insufficiency acute ": 21.3103035724141, "Adverse event ": 5.021723104558758, "Autoimmune colitis ": 250.55159493718256, "Autoimmune hepatitis ": 27.81665257726338, "Blood sodium decreased ": 2.480488946750292, "Blood thyroid stimulating hormone decreased ": 15.645556184679588, "Colitis ": 106.40084007570152, "Colitis ulcerative ": 4.756232395930666, "Conjunctivitis ": 3.0194215175323427, "Death ": 7.314046515584372, "Dehydration ": 2.942478250078489, "Dermatitis ": 2.7729989938775077, "Diarrhoea ": 5.71360276227037, "Diarrhoea haemorrhagic ": 7.462390705172848, "Encephalitis ": 3.6112130804300513, "Endocrine disorder ": 46.589106690286464, "Enteritis ": 6.830994180042691, "Enterocolitis ": 80.62849752865445, "Enterocolitis haemorrhagic ": 37.19148447662393, "General physical health deterioration ": 2.561426451371126, "Guillain-Barre syndrome ": 4.97783944956507, "Hepatic cytolysis ": 3.0311805394802147, "Hepatic failure ": 4.671356820221756, "Hepatitis ": 8.581449838269881, "Hepatotoxicity ": 6.895680990131609, "Hospitalisation ": 2.899782529060089, "Hyperthyroidism ": 3.9315876592628114, "Hypertransaminasaemia ": 6.916256578616816, "Hypophysitis ": 349.16454064114987, "Hypopituitarism ": 131.1982648591851, "Hypothalamo-pituitary disorder ": 56.0289313002347, "Hypothyroidism ": 5.031543586318606, "Immune-mediated enterocolitis ": 9.312142354077356, "Intentional product use issue ": 3.471437852717989, "Intestinal perforation ": 62.87074018415184, "Large intestine perforation ": 33.74146528597284, "Liver disorder ": 2.1825646687641305, "Liver function test increased ": 3.66705152791576, "Lymphocytic hypophysitis ": 83.95034300033848, "Malignant melanoma ": 2.4404107321332678, "Malignant neoplasm progression ": 52.809348812424254, "Meningitis ": 6.01690293636279, "Metastases to central nervous system ": 44.140995296166736, "Metastases to liver ": 3.2572757699936377, "Metastases to lung ": 6.801163194434338, "Metastasis ": 6.750475518621078, "Neoplasm ": 5.372987939217346, "Neuropathy peripheral ": 2.409754364521019, "Peritonitis ": 6.7155303973396485, "Pleural effusion ": 2.1793372659633947, "Pneumonitis ": 7.427405654605455, "Prescribed overdose ": 32.797987113559344, "Sepsis ": 2.089961680948217, "Thyroid disorder ": 6.7735081084961655, "Thyroiditis ": 6.955764566201648, "Uveitis ": 5.682803675190282, "Vitiligo ": 30.315521759509934, "Weight decreased ": 2.176922518401426}
\ No newline at end of file
+{"Acute kidney injury": 20.09568862652269, "Anuria": 95.8692694470784, "Hyperkalaemia": 23.12223140567722, "Hypoglycaemia": 12.429759756931611, "International normalised ratio increased": 23.44174657935997, "Pancreatitis acute": 63.37477913824392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/118.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/118.json
index fe53bf9b0d8..2c658318e3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/118.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/118.json
@@ -1 +1 @@
-{"Acquired immunodeficiency syndrome ": 4.597739131253828, "Acute kidney injury ": 4.097210202902976, "Agoraphobia ": 2.5058549132211643, "Albuminuria ": 4.004929530804365, "Alveolar bone resorption ": 17.917449050920517, "Anaemia of chronic disease ": 2.719320791645615, "Anhedonia ": 62.04720501322591, "Ankle fracture ": 20.673477754037624, "Anxiety ": 9.981756945498146, "Avulsion fracture ": 24.29589967410996, "Blood creatine increased ": 4.103694418045182, "Blood creatinine abnormal ": 4.260021302812305, "Blood creatinine increased ": 8.230139590679972, "Bone deformity ": 4.20988270138978, "Bone demineralisation ": 74.29079661197093, "Bone density abnormal ": 57.33276829701274, "Bone density decreased ": 78.92184879562389, "Bone disorder ": 28.906023333376645, "Bone fragmentation ": 14.614271483527272, "Bone infarction ": 9.526918499842992, "Bone loss ": 64.03061146942787, "Bone metabolism disorder ": 6.875897753192371, "CD4 lymphocytes abnormal ": 14.30317134192232, "CD4 lymphocytes decreased ": 2.9978228154580413, "Calcium deficiency ": 3.749160713369047, "Cervical radiculopathy ": 3.467042123751412, "Cervical spinal stenosis ": 6.869822920980888, "Cervical vertebral fracture ": 5.562828680428085, "Chronic kidney disease ": 54.30446761194408, "Chronic kidney disease-mineral and bone disorder ": 48.94111877355381, "Clavicle fracture ": 16.9479262962467, "Compression fracture ": 4.588244855906956, "Congenital cystic kidney disease ": 4.272700865399618, "Craniofacial fracture ": 10.843770904310936, "Decreased activity ": 10.947278419036037, "Degenerative bone disease ": 42.43603717294686, "Dental caries ": 17.30665710542336, "Dental pulp disorder ": 41.02140207839055, "Dysstasia ": 3.244647847573258, "Economic problem ": 51.50605071771121, "Emotional distress ": 45.88186816707796, "Enamel anomaly ": 4.178229096643428, "End stage renal disease ": 34.00985503547428, "Enzyme level increased ": 2.619683825434016, "Fanconi syndrome ": 2.3685670291799097, "Fanconi syndrome acquired ": 19.70103286837864, "Fat redistribution ": 4.2693812827298725, "Fear-related avoidance of activities ": 29.39543780462354, "Femoral neck fracture ": 3.934697545049544, "Femur fracture ": 4.912562207644121, "Fibula fracture ": 27.27290901990138, "Foot fracture ": 26.790592196425827, "Forearm fracture ": 15.183971852453237, "Fracture ": 25.28911419457833, "Fracture pain ": 4.322916990169276, "Fractured coccyx ": 10.8046082759269, "Fractured sacrum ": 9.074323540278211, "Genotype drug resistance test positive ": 2.8460984090956205, "Glomerular filtration rate abnormal ": 29.376490636131688, "Glomerular filtration rate decreased ": 4.8327112381646975, "Glomerular filtration rate increased ": 9.139097611744242, "Glycosuria ": 4.516974126708405, "Hand fracture ": 37.6019804961547, "Hip arthroplasty ": 10.137294714304495, "Hip fracture ": 7.150697716045842, "Hip surgery ": 2.4156702687435168, "Humerus fracture ": 10.63627156988016, "Hydronephrosis ": 2.0739293236879965, "Hyperparathyroidism ": 3.728920468137089, "Hyperparathyroidism secondary ": 12.726096951404992, "Hypertensive nephropathy ": 5.81513219828528, "Immune reconstitution inflammatory syndrome ": 2.085008705322505, "Intervertebral disc degeneration ": 16.00146844249128, "Intervertebral disc protrusion ": 2.168589481816562, "Intervertebral disc space narrowing ": 2.8791322446840857, "Jaw fracture ": 16.89673923512782, "Kidney small ": 7.327498114953578, "Limb fracture ": 30.61004843188345, "Loose tooth ": 2.1690106094917314, "Loss of personal independence in daily activities ": 2.3981231852904603, "Lower limb fracture ": 8.79094575229899, "Lumbar spinal stenosis ": 3.825423780632272, "Lumbar vertebral fracture ": 4.74401153220382, "Medical diet ": 14.769176305851964, "Multiple fractures ": 63.59495811946002, "Nephrectomy ": 3.198458489711401, "Nephrogenic anaemia ": 13.785214180238956, "Nephrolithiasis ": 3.3988420190678585, "Nephropathy ": 41.3887994361458, "Osteoarthritis ": 7.662655291517863, "Osteochondrosis ": 2.5701721111532385, "Osteogenesis imperfecta ": 2.585485204882509, "Osteomalacia ": 34.368516648652104, "Osteonecrosis ": 53.32525997511447, "Osteopenia ": 68.31019063939806, "Osteoporosis ": 48.2989046874149, "Osteoporotic fracture ": 25.654815836290396, "Pain ": 4.198385354821227, "Partner stress ": 2.734755129734826, "Patella fracture ": 10.587732344437724, "Patellofemoral pain syndrome ": 3.1221547288735256, "Pathological fracture ": 6.539336186316638, "Pelvic fracture ": 2.069212464389205, "Periodontal disease ": 3.058779080546067, "Pituitary-dependent Cushing's syndrome ": 2.7535466194941174, "Poor dental condition ": 9.92006364782072, "Posterior tibial tendon dysfunction ": 56.94605046303012, "Pregnancy with implant contraceptive ": 5.340970659714591, "Protein total abnormal ": 43.5989040572801, "Protein total increased ": 18.3844909322867, "Protein urine present ": 5.3953293617237055, "Proteinuria ": 5.9216403271562585, "Pulpless tooth ": 6.9454398154350185, "Quality of life decreased ": 13.160117790790572, "Radius fracture ": 21.679412632250795, "Renal atrophy ": 7.678372007290936, "Renal cyst ": 8.599351473558642, "Renal failure ": 20.318526495366758, "Renal impairment ": 6.522784237835131, "Renal injury ": 99.81318656530578, "Renal mass ": 5.437195601084016, "Renal transplant ": 4.142595447806777, "Renal tubular acidosis ": 4.802415964175574, "Renal tubular disorder ": 2.699799105229941, "Renal tubular dysfunction ": 6.675385441387734, "Renal tubular injury ": 13.385763089139475, "Renal tubular necrosis ": 3.3588853086579697, "Rib fracture ": 14.367268478849308, "Scapula fracture ": 23.309734854504462, "Shoulder arthroplasty ": 5.263334162118969, "Shoulder fracture ": 10.35315155808041, "Sitting disability ": 6.293584189671739, "Skeletal injury ": 114.8498199553552, "Skull fracture ": 2.408687156980318, "Spinal column injury ": 5.472019407686605, "Spinal compression fracture ": 7.208886660711597, "Spinal deformity ": 2.991122738699659, "Spinal fracture ": 5.709313813255997, "Spinal fusion surgery ": 2.307573067065805, "Spinal osteoarthritis ": 10.124938645459425, "Spinal stenosis ": 5.517703497010627, "Spondylitic myelopathy ": 31.003153552017856, "Spondylolisthesis ": 12.804722585507765, "Spondylolysis ": 13.641233563602716, "Stress fracture ": 12.024331876018335, "T-lymphocyte count decreased ": 5.657631964314568, "Teeth brittle ": 36.19989430414055, "Thoracic vertebral fracture ": 6.744285537957572, "Tibia fracture ": 21.433211205973333, "Tooth disorder ": 2.7618408752834807, "Tooth erosion ": 2.060900128466028, "Tooth extraction ": 8.557413172010012, "Tooth fracture ": 35.97492952177401, "Tooth impacted ": 10.06724456053118, "Tooth injury ": 843.0683356298147, "Tooth loss ": 86.98250481022028, "Traumatic fracture ": 2.3314990671403426, "Ulna fracture ": 18.301690014399345, "Underweight ": 8.116249260535712, "Unemployment ": 12.338751234123718, "Upper limb fracture ": 8.624920736524158, "Vertebral foraminal stenosis ": 14.771258551862829, "Vertebral osteophyte ": 4.343362834592239, "Viral load increased ": 2.937051567944192, "Virologic failure ": 2.0640077732999016, "Vitamin D decreased ": 2.876135009724897, "Vitamin D deficiency ": 52.40866713315488, "Wrist fracture ": 25.625364501547597}
\ No newline at end of file
+{"Abdominal pain": 3.426539250396288, "Anaemia": 4.563316572766663, "Ankylosing spondylitis": 32.77299868244631, "Balance disorder": 2.379292701814556, "Candida infection": 10.793484208941113, "Colitis": 7.353632542758248, "Constipation": 8.098230319904005, "Cytokine release syndrome": 6.161973818140658, "Cytomegalovirus infection": 19.062053194615693, "Dehydration": 3.5024827283545834, "Diarrhoea": 2.46595417620883, "Disease progression": 15.046580992898104, "Dysphagia": 2.381758276940918, "Ear pain": 4.110325234305359, "Febrile neutropenia": 2.8199152235803773, "Haemoglobin decreased": 2.098973313081164, "Hepatitis": 6.285285375742584, "Hydronephrosis": 26.313559263725868, "Hyperthyroidism": 8.25653582889938, "Hypokalaemia": 5.310299828312972, "Hypomagnesaemia": 54.70630955018757, "Hyponatraemia": 3.2979653645307567, "Hypothyroidism": 5.276465839346902, "Infusion related reaction": 5.881201339089353, "Intentional product use issue": 3.1791809195991423, "Jaundice": 2.471010583624879, "Lymphoma transformation": 1595.2712923362303, "Malignant neoplasm progression": 4.6919584958277145, "Metastases to liver": 6.000978098293316, "Metastases to lung": 10.14537471708999, "Mouth ulceration": 8.218892046920114, "Mucosal inflammation": 19.525527304589797, "Neoplasm": 20.44049801996021, "Nervous system disorder": 9.808601536112944, "Neuropathy peripheral": 3.158432318365032, "Neutropenic sepsis": 42.49001034979912, "Neutrophil count decreased": 7.126638846722933, "Pneumonitis": 11.95312957917767, "Product use in unapproved indication": 2.3701582013658684, "Productive cough": 4.638383271499942, "Sepsis": 3.7005076626514577, "Skin candida": 424.7497219051046, "Skin toxicity": 34.05166204559813, "Stomatitis": 2.09132186730812, "Upper respiratory tract infection": 4.909671121884552, "White blood cell count decreased": 2.5620389904673067}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1180.json
index ab7d92f8242..35fba38a131 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1180.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 3.5334053952819207, "Agitation ": 2.888920676884368, "Alanine aminotransferase abnormal ": 29.440642694940514, "Aphasia ": 13.946453313172247, "Aspartate aminotransferase increased ": 2.367820508889373, "Aspergillus infection ": 5.149610333616589, "B-cell aplasia ": 105.01606126652784, "B-cell lymphoma ": 25.700012548907285, "Bacteraemia ": 8.802988200883284, "Bone marrow failure ": 12.491171229720694, "Bradykinesia ": 15.289778675334308, "Bradyphrenia ": 17.15757591743116, "Brain oedema ": 8.70466275827124, "Clostridium difficile colitis ": 2.965516752817785, "Clostridium difficile infection ": 3.146396404017156, "Coagulopathy ": 2.284966711588554, "Confusional state ": 3.431549087613782, "Cytokine release syndrome ": 1132.215433833366, "Cytokine storm ": 113.96681113744314, "Cytomegalovirus infection reactivation ": 8.17698841467584, "Cytopenia ": 31.33116623690948, "Death ": 3.5292376209164846, "Depressed level of consciousness ": 2.747902572659217, "Diffuse large B-cell lymphoma ": 88.44877055912738, "Diffuse large B-cell lymphoma recurrent ": 37.29693213465015, "Disease progression ": 15.335334935028651, "Disease recurrence ": 5.695378780197661, "Disorientation ": 4.217527845458372, "Disseminated intravascular coagulation ": 3.3469378820965554, "Dysgraphia ": 49.00119438871456, "Encephalopathy ": 27.64547330737424, "Febrile neutropenia ": 6.44990512549063, "Haemophagocytic lymphohistiocytosis ": 29.78905983703002, "Hyperbilirubinaemia ": 3.793739634463942, "Hypertransaminasaemia ": 4.145280065610461, "Hypervolaemia ": 4.527191962245125, "Hypoalbuminaemia ": 21.912588334117206, "Hypogammaglobulinaemia ": 78.53503916656763, "Hypotension ": 3.397055144219587, "Hypoxia ": 8.396987476281254, "Immune effector cell-associated neurotoxicity syndrome ": 2252.4733315214685, "Incontinence ": 13.276346641173468, "Infection ": 2.92690775161163, "Lymphoma ": 12.77224862846974, "Memory impairment ": 2.343798909178276, "Mental status changes ": 8.193608969219776, "Multiple organ dysfunction syndrome ": 3.287513838781345, "Myelodysplastic syndrome ": 5.69639157441125, "Nervous system disorder ": 3.036023505601178, "Neurological symptom ": 3.932976493530116, "Neurotoxicity ": 343.4460247622447, "Neutropenia ": 4.726416336561662, "Pancytopenia ": 7.294153515095287, "Pleural effusion ": 2.4143088169479467, "Primary mediastinal large B-cell lymphoma ": 376.71858990274416, "Sepsis ": 3.0186360400002594, "Septic shock ": 5.950482192849383, "Serum ferritin increased ": 9.292896250720664, "Status epilepticus ": 2.47426321594554, "Systemic candida ": 15.470756552538058, "Tachycardia ": 2.2369791658611637, "Tachypnoea ": 3.25688135546752, "Therapy non-responder ": 2.5553856275398177, "Therapy partial responder ": 3.696353065879283, "Thrombocytopenia ": 2.035956666188308, "Tremor ": 2.9958551438361463}
\ No newline at end of file
+{"Abdominal hernia": 2.8837374521929737, "Abnormal faeces": 2.392530819149343, "Abscess limb": 2.5025968224010438, "Accident": 6.441404203718624, "Accident at work": 2.914947536926745, "Acne": 4.822679631666355, "Animal bite": 7.165020752222783, "Ankle fracture": 3.940309813247728, "Ankylosing spondylitis": 2.155713088588961, "Anorectal disorder": 2.310886177790797, "Aortic aneurysm": 2.0230702929289097, "Aphonia": 2.5103221883734976, "Appendicitis perforated": 4.250062853263765, "Arthritis": 4.122081558731002, "Arthritis bacterial": 3.644751005460785, "Arthritis infective": 14.234747362683532, "Arthropathy": 3.1560072853776484, "Arthropod bite": 4.090575124560802, "Back disorder": 4.741366052569219, "Back injury": 2.2262007125173766, "Bacterial infection": 2.4600464873595635, "Basal cell carcinoma": 3.391464296877209, "Blindness": 2.2729967199252514, "Blood cholesterol abnormal": 3.745472082769663, "Blood cholesterol increased": 4.251765446854117, "Blood iron decreased": 3.395330508445022, "Blood pressure abnormal": 2.22553656850416, "Blood test abnormal": 2.9188413749728674, "Body height decreased": 4.108922759887753, "Bone deformity": 6.15747417938938, "Bone disorder": 3.235393923921121, "Bowel movement irregularity": 11.482478671492368, "Breast cancer female": 7.835227555491443, "Bronchial disorder": 4.439763536856914, "Bronchitis": 5.286394890742678, "C-reactive protein decreased": 3.9372915336234926, "C-reactive protein increased": 3.058166996551458, "Cardiac disorder": 2.1057201034271458, "Carpal tunnel syndrome": 4.703440015597934, "Cartilage injury": 4.888742459165624, "Cataract": 4.189414149426043, "Cellulitis": 3.846331673715104, "Change of bowel habit": 3.929528499437677, "Chest injury": 4.477748079362383, "Chondropathy": 5.71163913905201, "Circumstance or information capable of leading to medication error": 2.4532689919476094, "Clostridium difficile infection": 4.693789020244809, "Coccidioidomycosis": 10.41955380326084, "Colectomy": 13.198142998667349, "Colitis ulcerative": 11.025945558038677, "Colon cancer": 2.640231325599843, "Colon injury": 14.84940146683996, "Colostomy": 4.496279627353837, "Concussion": 2.364832843242189, "Condition aggravated": 9.21956343128859, "Crohn's disease": 2.334997737413759, "Cyst": 4.11087418204537, "Cystitis": 6.145813706487544, "Deafness": 2.088310516083637, "Decreased immune responsiveness": 10.188951469735931, "Defaecation urgency": 9.215672312429469, "Dementia": 2.927078286129711, "Dementia Alzheimer's type": 3.300590187517864, "Dental operation": 6.621444420171007, "Dermatomyositis": 2.662911599935046, "Diabetes mellitus": 2.4860695143431766, "Diarrhoea haemorrhagic": 2.7409318352565357, "Discouragement": 28.66488865384152, "Disease recurrence": 4.981710010976043, "Diverticulitis": 7.399133547917933, "Diverticulum": 2.344484492610393, "Drug effect less than expected": 2.338231281856028, "Drug effective for unapproved indication": 13.77570587592441, "Drug ineffective": 2.2277565475756567, "Dysgraphia": 3.483087668111357, "Dysstasia": 2.131529715321447, "Ear disorder": 2.511131425629038, "Ear infection": 4.161364056710985, "Embolism venous": 2.6963874119139417, "Endometrial cancer": 2.7478744826188293, "Energy increased": 3.321212271238428, "Enteritis infectious": 7.408052506820002, "Escherichia infection": 2.937236861029372, "Exostosis": 2.3877698561179064, "Exposure to SARS-CoV-2": 3.707403937381688, "Eye disorder": 2.0842851381664573, "Eye infection": 7.879992738330348, "Eye operation": 4.18850389425756, "Faecal calprotectin increased": 26.227119525057848, "Faeces pale": 2.1372080246099943, "Faeces soft": 4.560758647460472, "Fall": 3.056917039886388, "Femur fracture": 3.2992927743073546, "Fibromyalgia": 2.3882262325419377, "Fibula fracture": 2.2613397808861437, "Finger deformity": 10.229696425929305, "Fistula": 2.5373645999125016, "Flatulence": 2.3787364226860657, "Food poisoning": 3.2618134432736734, "Foot deformity": 7.956546115312522, "Foot fracture": 3.35175163406755, "Foot operation": 7.889994784542765, "Frequent bowel movements": 10.326830726255375, "Frustration tolerance decreased": 2.3802364664172453, "Functional gastrointestinal disorder": 2.2770319143352507, "Fungal foot infection": 8.167187275228661, "Fungal infection": 2.8633427657959003, "Furuncle": 3.81059626690815, "Gait disturbance": 2.911362596872134, "Gait inability": 4.451775321529252, "Gallbladder disorder": 2.8332988935768126, "Gastric infection": 8.39051971112481, "Gastric ulcer": 2.1746675150777057, "Gastroenteritis viral": 3.550538916958005, "Gastrointestinal disorder": 2.279397487190133, "Gastrointestinal infection": 3.5724520560017154, "Gastrointestinal perforation": 4.025802609356632, "Glaucoma": 2.3799662718851518, "Grip strength decreased": 3.4727923717025067, "Haematochezia": 8.013486725307432, "Haemorrhoids": 2.015030974891797, "Hair growth abnormal": 2.56580013425024, "Hand fracture": 2.3396441058608803, "Hernia": 5.032247517570047, "Herpes ophthalmic": 5.47635488976758, "Herpes virus infection": 2.489740750606883, "Herpes zoster": 3.833068933253675, "Herpes zoster disseminated": 4.145534360985906, "Hip arthroplasty": 2.7117703209909, "Hip fracture": 4.683704862035591, "Hip surgery": 5.591662547681602, "Hordeolum": 3.0008036569644183, "Hypoacusis": 4.138221430815063, "Hypokinesia": 2.070160862577704, "Ileostomy": 7.213463462600584, "Illness": 5.487860419649216, "Immune system disorder": 6.306070419842226, "Immunodeficiency": 2.999950839941079, "Immunosuppression": 11.31408529049527, "Impaired healing": 2.265318330541839, "Impaired quality of life": 3.1673472606735062, "Increased tendency to bruise": 2.4480115133677045, "Infected bite": 9.527764715352854, "Infected skin ulcer": 8.245967922716813, "Infection": 5.054795697044059, "Inflammation": 3.0927016975040424, "Inflammatory bowel disease": 2.799091818244326, "Inflammatory marker increased": 4.3275354217436455, "Influenza": 2.5374097544710894, "Intentional dose omission": 10.243679903439002, "Intentional product misuse": 4.379137296804797, "Intentional product use issue": 2.153782772987741, "Intervertebral disc degeneration": 2.40146723515131, "Intervertebral disc disorder": 2.6808684956244457, "Intervertebral disc protrusion": 3.769788022619701, "Intestinal perforation": 2.9454112278608027, "Intestinal resection": 3.507109726278421, "Intracranial aneurysm": 2.280683351010586, "Joint abscess": 21.032903576104804, "Joint destruction": 4.924543241345287, "Joint dislocation": 5.645951220706646, "Joint effusion": 4.045972739242057, "Joint injury": 6.665940587540864, "Joint lock": 4.297236570338184, "Joint noise": 3.4600512196386384, "Joint range of motion decreased": 3.316440794065078, "Joint stiffness": 2.5557002983096604, "Joint swelling": 3.2873854868523016, "Kidney infection": 9.23069062273853, "Knee arthroplasty": 5.01771565688022, "Knee deformity": 5.358328606677833, "Knee operation": 11.374686550174312, "Laboratory test abnormal": 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2.1315597114809477, "Lymphoma": 4.034165207170942, "Malignant melanoma": 2.540562461121192, "Mean cell haemoglobin decreased": 2.6759222028009844, "Memory impairment": 2.848577458224465, "Meniscus injury": 5.2741619663013655, "Middle insomnia": 2.046663199343698, "Mobility decreased": 2.669620895775369, "Mucous stools": 12.604220810000747, "Muscle rupture": 4.2392293976289785, "Muscle strain": 4.128929795188474, "Musculoskeletal discomfort": 2.54766720811612, "Musculoskeletal disorder": 3.4343681415577905, "Musculoskeletal stiffness": 3.210049576832493, "Mutism": 2.4836872603540336, "Mycobacterial infection": 2.372496330009241, "Mycobacterium tuberculosis complex test positive": 4.207638492201945, "Nail infection": 9.918432866722828, "Nasal congestion": 2.863758819826529, "Nasopharyngitis": 5.250143162892647, "Near death experience": 2.6828317217502904, "Neck surgery": 5.402395134667284, "Neoplasm": 2.512431573449152, "Neoplasm malignant": 3.899584161136834, "Nephrolithiasis": 3.670221436467374, "Nerve compression": 7.294766559017453, "Neuroendocrine carcinoma of the skin": 5.985089444831888, "Nodule": 4.306715896653896, "Onychomycosis": 2.090315888198559, "Ophthalmic herpes zoster": 4.478074845430009, "Oral herpes": 2.9014939263670025, "Oral infection": 4.85542441039379, "Oral surgery": 6.935425797341101, "Osteitis": 2.3808028403306034, "Osteoarthritis": 6.0892012879426645, "Osteomyelitis": 4.740734318208935, "Pain": 2.0807475760896765, "Pancreatic disorder": 2.158852590551485, "Parkinson's disease": 2.072278281689352, "Patella fracture": 4.412031559140672, "Pelvic fracture": 8.052389596289583, "Peripheral swelling": 2.7670178841474726, "Pharyngeal disorder": 3.3043807760556003, "Pharyngitis streptococcal": 8.58749260771413, "Plantar fasciitis": 2.5758096219927307, "Pneumonia": 4.145672157666236, "Pneumonia bacterial": 2.169862894130245, "Pneumonia fungal": 2.6587647413765243, "Polyarthritis": 2.854896107238248, "Polyp": 3.879219777443032, "Post procedural complication": 4.042585796837883, "Post procedural infection": 9.683612925116764, "Postoperative wound infection": 5.952842732383256, "Pre-existing condition improved": 11.384730756368793, "Precancerous skin lesion": 7.301578596903173, "Product administration interrupted": 3.620117921578466, "Product dispensing error": 4.141014331122789, "Product dispensing issue": 10.823003110700968, "Product dose omission in error": 29.36332601963902, "Product dose omission issue": 4.909704198333924, "Product prescribing error": 3.911230820200182, "Product prescribing issue": 4.481145876880671, "Product use issue": 2.0511055531785223, "Pulmonary fibrosis": 2.2102969357954225, "Pulmonary mass": 2.1886254155836475, "Pulmonary thrombosis": 4.894234048440405, "Pyelonephritis acute": 2.0291378587991566, "Rectal haemorrhage": 3.449714732944801, "Red blood cell sedimentation rate increased": 7.056912201663936, "Red cell distribution width increased": 3.271306591614134, "Renal disorder": 2.032674053938748, "Respiratory tract congestion": 3.105213828048882, "Respiratory tract infection": 5.279282044852707, "Rheumatoid arthritis": 9.682948023637778, "Rheumatoid factor increased": 4.314249188528619, "Rheumatoid lung": 15.223563629562108, "Rheumatoid nodule": 3.206025865469213, "Rhinorrhoea": 2.305155560770383, "Rib fracture": 4.5024582124805255, "Road traffic accident": 2.4554354666601514, "Root canal infection": 15.5947126452508, "Rosacea": 3.6028672039732297, "Rotator cuff repair": 7.314887554218812, "Rotator cuff syndrome": 3.5599127595359463, "Sciatica": 3.385834904086282, "Seasonal allergy": 2.321015128880997, "Secretion discharge": 2.0135399321394467, "Sensitivity to weather change": 74.7837466638745, "Serum ferritin decreased": 4.377207766581791, "Shoulder arthroplasty": 6.9100104172608745, "Shoulder fracture": 5.784968097475387, "Shoulder operation": 7.962624297968636, "Sinus congestion": 3.078780900728268, "Sinus disorder": 5.122876327078184, "Sinusitis": 5.763707778697701, "Sinusitis bacterial": 11.754447949245709, "Sjogren's syndrome": 5.333067034199377, "Skin cancer": 12.0864299518885, "Skin infection": 5.162457437892608, "Skin laceration": 2.174117024353873, "Skin lesion": 2.18653659633868, "Skin papilloma": 2.4223253582024804, "Spinal column injury": 2.16791202502268, "Spinal disorder": 5.825660251491167, "Spinal fracture": 4.879071051443314, "Spinal fusion surgery": 4.389081199067828, "Spinal operation": 8.363141088269744, "Spinal osteoarthritis": 2.234923257509488, "Spinal stenosis": 4.516670576607373, "Spondylitis": 3.2985894268541966, "Squamous cell carcinoma": 2.9924773028610328, "Squamous cell carcinoma of skin": 2.8785920852918143, "Staphylococcal infection": 3.1311888263918357, "Stress": 4.405579955522297, "Stress fracture": 3.1722264340431803, "Synovial cyst": 7.05331859796084, "Synovitis": 2.1972923458187, "Therapeutic product effect delayed": 12.893422845406205, "Therapeutic product effect incomplete": 10.41645584293121, "Therapeutic response shortened": 3.0170947112068576, "Therapeutic response unexpected": 4.032259106394067, "Thrombosis": 2.9075950038944147, "Tibia fracture": 2.723282264684895, "Tooth abscess": 12.171259304821907, "Tooth disorder": 2.827244182047453, "Tooth infection": 9.753419617754744, "Trigger finger": 8.09884625291275, "Tuberculin test positive": 4.125238400753922, "Tuberculosis": 6.059747819163714, "Ulcer": 2.080804841943578, "Upper limb fracture": 5.479339859334818, "Upper respiratory tract congestion": 3.791142913624001, "Upper respiratory tract infection": 4.699240674108017, "Urinary tract infection": 5.310765302326998, "Urinary tract infection bacterial": 5.655407945222626, "Vaginal infection": 2.290629068954235, "Vein rupture": 3.3545292094536623, "Viral infection": 4.501203404152633, "Viral upper respiratory tract infection": 4.731286894412238, "Vitamin D decreased": 3.324769462481888, "Walking aid user": 2.8852050200543924, "Weight fluctuation": 2.108941469063104, "Weight increased": 2.40868769576847, "Wound infection": 6.105363076197313, "Wound secretion": 4.196274790902783, "Wrist fracture": 3.843911012183144, "Wrong dose": 2.2819033598978127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1181.json
index a89aad965d3..dc0feb1dc60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1181.json
@@ -1 +1 @@
-{"Acute kidney injury ": 5.096166118004733, "Alanine aminotransferase increased ": 6.042228462807276, "Anaemia ": 3.998053285368551, "Aspartate aminotransferase increased ": 4.863140768882386, "Blood alkaline phosphatase increased ": 7.09801570466784, "Blood bilirubin increased ": 4.467904246632971, "Blood creatine phosphokinase increased ": 19.163283829621587, "Capillary leak syndrome ": 78.05570506736963, "Cardiac failure ": 5.4906114744960695, "Catheter site erythema ": 82.19907633765617, "Cholestasis ": 8.78889935741572, "Disease progression ": 5.430112799785632, "Extravasation ": 219.13372806767552, "Febrile neutropenia ": 11.031648660353635, "Gamma-glutamyltransferase increased ": 6.669493541020436, "Haematotoxicity ": 27.102429169140475, "Hepatic cytolysis ": 19.964846515916463, "Hepatic enzyme increased ": 3.4749654815084074, "Hepatic failure ": 11.40502088599487, "Hepatic function abnormal ": 3.702116887134036, "Hepatotoxicity ": 19.531439013723443, "Hypertransaminasaemia ": 26.536317994353084, "Infusion site extravasation ": 170.21029631779604, "Leukopenia ": 5.256302080622599, "Multiple organ dysfunction syndrome ": 8.030080488581554, "Myelosuppression ": 4.890360513337416, "Neutropenia ": 14.22905547140738, "Neutropenic sepsis ": 40.93582995344361, "Neutrophil count decreased ": 3.963931140250513, "Pancytopenia ": 21.793830302109644, "Platelet count decreased ": 2.8349447596269224, "Pleural effusion ": 3.156311965447801, "Pulmonary embolism ": 2.0523336845785307, "Renal failure ": 3.931701952138176, "Rhabdomyolysis ": 49.58194982393093, "Sarcoma ": 123.17448561593534, "Sepsis ": 5.464519096291464, "Septic shock ": 5.198717897605632, "Thrombocytopenia ": 8.658436094116635, "Transaminases increased ": 20.572968040246952}
\ No newline at end of file
+{"Angina pectoris": 2.2384108583098943, "Blood bilirubin increased": 2.362730285734237, "Cardiotoxicity": 8.364532985830472, "Colitis": 2.2421253890274877, "Cytopenia": 3.4029658169104597, "Decreased appetite": 3.0375208785619394, "Dehydration": 5.500223922828542, "Diarrhoea": 5.185880408195997, "Dihydropyrimidine dehydrogenase deficiency": 558.2720644150886, "Disease progression": 3.4205536594812105, "Disseminated intravascular coagulation": 4.980523480836592, "Drug interaction": 3.062848114406834, "Drug-induced liver injury": 2.481120573632713, "Enteritis": 13.7171912538231, "Enterocolitis": 15.604784290694685, "Faecal volume decreased": 255.86707061670367, "Febrile neutropenia": 4.032253310476976, "Formication": 4.762352058622428, "Gastrointestinal disorder": 2.898854773909117, "Granulocyte count decreased": 20.84968282235198, "Granulocytopenia": 9.19988947578254, "Hepatic function abnormal": 6.779865604880881, "Hepatic lesion": 9.691426315849826, "Hyperbilirubinaemia": 3.171059135469399, "Ileus": 5.047902978645126, "Intentional product use issue": 2.107817980361163, "International normalised ratio increased": 4.347527932144155, "Interstitial lung disease": 2.612142748915216, "Intestinal obstruction": 2.724589771920116, "Leukoencephalopathy": 12.439607280393512, "Leukopenia": 3.281936164086064, "Liver injury": 2.1875435848493927, "Metastases to liver": 2.7565281006463964, "Mouth ulceration": 2.1701152747591235, "Mucosal inflammation": 12.440914443245743, "Myelosuppression": 58.189299880052815, "Neuropathy peripheral": 5.41535756653951, "Neurotoxicity": 7.1808520378960266, "Neutropenia": 6.093800079966844, "Neutrophil count decreased": 15.836277166201668, "Palmar-plantar erythrodysaesthesia syndrome": 21.2059160599237, "Pancytopenia": 3.3775782223168496, "Platelet count decreased": 18.03954869374636, "Polyneuropathy": 3.27974274011786, "Prothrombin time prolonged": 8.384464030534312, "Retching": 2.153909571237612, "Sensory disturbance": 2.5989980533656034, "Sepsis": 2.075543772288573, "Septic shock": 3.3915362479540616, "Stomatitis": 5.051706541413796, "Thrombocytopenia": 4.976203901208343, "Vomiting": 2.914426484594333, "White blood cell count decreased": 12.905969957567365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1182.json
index 2d1c899c7b4..1e4058b5d1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1182.json
@@ -1 +1 @@
-{"Thrombocytopenia ": 33.6963348638808}
\ No newline at end of file
+{"Drug interaction": 32.58711593822185, "Drug level decreased": 155.18513374722136, "International normalised ratio increased": 19.50159743590104, "Renal failure": 2.9713598274169324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1183.json
index c529c9b8104..a758675642a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1183.json
@@ -1 +1 @@
-{"Disease progression ": 66.12009232952163, "Pancytopenia ": 42.12177304765153}
\ No newline at end of file
+{"Completed suicide": 4.033331950118586, "Drug interaction": 2.736196017149354, "Electrocardiogram QT prolonged": 6.694905452022044, "Extrapyramidal disorder": 53.19828458071488, "Neuroleptic malignant syndrome": 37.12060238203841, "Overdose": 2.8464849965704224, "Product use in unapproved indication": 2.3755661573058515, "Psychiatric symptom": 61.4738604159204, "Psychotic disorder": 20.386707798002, "Restlessness": 8.82870357852778, "Rhabdomyolysis": 11.90145791408296, "Schizophrenia": 108.64342338680372, "Suicidal ideation": 4.61463585452843, "Suicide attempt": 7.852130505708266, "Weight increased": 4.929064803427889}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1184.json
index d3d1f91e690..29ade031790 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1184.json
@@ -1 +1 @@
-{"Intentional overdose ": 17.66585940476954, "Somnolence ": 6.366280307194479, "Tachycardia ": 7.297925207129911}
\ No newline at end of file
+{"Diarrhoea": 8.022824619619023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1185.json
index 28e7b7bca89..d6ea4c55d84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1185.json
@@ -1 +1 @@
-{"Completed suicide ": 83.49165343645447, "Toxicity to various agents ": 16.427490773455173}
\ No newline at end of file
+{"Back pain": 2.935845632824664, "Hot flush": 10.009537814005284, "Hypocalcaemia": 45.58729986690024, "Malignant neoplasm progression": 7.224431708774694, "Metastases to bone": 23.43139547256248, "Osteonecrosis of jaw": 189.02555822628665, "Prostatic specific antigen increased": 76.98881335539022}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1186.json
index e742a0cf95d..7ce869733ca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1186.json
@@ -1 +1 @@
-{"Asthenia ": 2.1675024286621385, "Diarrhoea ": 7.946974230389584, "Hypertension ": 5.39447631711572, "Neuropathy peripheral ": 9.423157485279408, "Neutropenia ": 12.688046669023231, "Neutrophil count decreased ": 13.902036354182746, "Proteinuria ": 34.85095200530019, "Thrombocytopenia ": 4.171631462935892}
\ No newline at end of file
+{"Dupuytren's contracture": 1015.0574975032964, "Haematoma": 29.5885108338494, "Hypersensitivity": 3.46007082119764, "Pain in extremity": 2.0482857705877904, "Penile contusion": 5477.844931612342, "Penile haematoma": 2783.614869252263, "Penile pain": 436.1699933696145, "Penile swelling": 1571.5565979304415, "Peripheral swelling": 6.27675194293081, "Skin laceration": 81.29900011033402, "Tendon rupture": 100.7051940880498}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1187.json
index c768e379d0c..981a0f4a911 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1187.json
@@ -1 +1 @@
-{"Nausea ": 4.846605938473601, "Respiratory depression ": 255.73332124954285}
\ No newline at end of file
+{"Lactic acidosis": 76.28632593236019}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1188.json
index 302c1e95c9d..c851f77bf2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1188.json
@@ -1 +1 @@
-{"Back pain ": 13.621316334841092, "Bone pain ": 32.51999598045862, "Chest pain ": 2.2365574421603203, "Drug ineffective ": 3.432491701158672, "Erythema ": 3.534933239769024, "Face oedema ": 6.011509277355587, "Febrile neutropenia ": 11.730560245907713, "Hypotension ": 2.1534228567747875, "Musculoskeletal chest pain ": 11.490152077859197, "Neck pain ": 2.236402243869809, "Neutropenia ": 9.617374177984958, "Neutrophil count decreased ": 2.969683931242883, "Pain ": 2.724640815870433, "Pelvic pain ": 25.0254999581374, "Pruritus ": 2.4757848287068525, "Rash maculo-papular ": 7.7295919859914495, "Syncope ": 2.198306704776937, "Therapy non-responder ": 5.865173859320756, "Urticaria ": 2.557703287386692}
\ No newline at end of file
+{"Platelet count decreased": 33.93475477427325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1189.json
index 3a232a152cc..378053ad3c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1189.json
@@ -1 +1 @@
-{"Condition aggravated ": 4.862491191696674, "Death ": 3.932510598955923, "Diarrhoea ": 4.774237620715573, "Disease progression ": 11.499081780696724, "Dysphagia ": 9.080036573708147, "Epilepsy ": 5.036546526054486, "Gait disturbance ": 2.393718534160985, "Gastrointestinal disorder ": 7.548389892201959, "Gastrostomy ": 255.98396991124983, "General physical health deterioration ": 4.599047971530279, "Neuropathy peripheral ": 2.856281903898004, "Niemann-Pick disease ": 73971.8608260369, "Pneumonia ": 4.756067784436551, "Pneumonia aspiration ": 17.203773895378895, "Respiratory failure ": 9.32677543544775, "Seizure ": 3.436968238746199, "Sepsis ": 2.961553670659813, "Thrombocytopenia ": 2.30505935295198, "Tremor ": 3.5466112609132905, "Weight decreased ": 9.606664910147456}
\ No newline at end of file
+{"Anaemia": 9.074151212624416, "Bedridden": 2.8851654539730327, "Blood alkaline phosphatase decreased": 168.1925427076586, "Blood alkaline phosphatase increased": 8.511961997703326, "Blood lactate dehydrogenase increased": 2.102879681179484, "Blood test abnormal": 11.548245860798938, "Bone marrow failure": 11.191806673675416, "Bone marrow infiltration": 191.63186198919604, "Bone pain": 11.589084110463023, "Cancer pain": 58.61362665818138, "Cytopenia": 3.028617536857068, "Death": 4.440666566954851, "Decreased appetite": 2.65919295287684, "Disease progression": 11.412760804851938, "Disseminated intravascular coagulation": 3.431733579833558, "Femur fracture": 3.914800425238691, "Fracture": 2.385089294128976, "Full blood count abnormal": 6.233720673247319, "General physical health deterioration": 19.88394878925993, "Haematotoxicity": 21.629561732648952, "Haemoglobin abnormal": 11.864105421691882, "Haemoglobin decreased": 13.407418123061667, "Hip fracture": 2.172773961450536, "Hormone-refractory prostate cancer": 2530.7950590700366, "Hospitalisation": 2.315985315993159, "Hydronephrosis": 8.67912569056462, "Laboratory test abnormal": 5.107633534309299, "Leukopenia": 3.3076424186462328, "Malignant neoplasm progression": 3.83177098721678, "Metastases to bone": 106.1885235553158, "Metastases to bone marrow": 112.14775325467676, "Metastases to central nervous system": 13.789509431424143, "Metastases to liver": 46.13333725429729, "Metastases to lung": 20.96973600594865, "Metastases to lymph nodes": 39.537118861861096, "Metastases to meninges": 26.33626632134654, "Metastases to spine": 72.39193727257059, "Metastasis": 56.153072190287546, "Musculoskeletal chest pain": 2.951175256135856, "Myelosuppression": 6.7194315192487, "Neutropenia": 2.574331111688125, "Neutrophil count decreased": 4.345723984297105, "No adverse event": 9.262809788397272, "Osteonecrosis of jaw": 41.58192692163472, "Pancytopenia": 9.636410146883472, "Pathological fracture": 42.75146840466586, "Pelvic pain": 4.166286162054194, "Physical deconditioning": 6.915306453406476, "Platelet count decreased": 10.09734864493156, "Pre-existing condition improved": 25.724739474041545, "Prostate cancer": 41.492892838745455, "Prostate cancer metastatic": 274.4932174182316, "Prostate cancer stage IV": 669.4171959392986, "Prostatic specific antigen increased": 245.9450899602774, "Red blood cell count decreased": 3.675930822729843, "Sepsis": 2.017631003272275, "Spinal compression fracture": 15.671315940287217, "Spinal cord compression": 125.78528886115907, "Spinal pain": 5.570224834524219, "Subdural haematoma": 3.643634650229967, "Thrombocytopenia": 6.966839332713939, "Transfusion": 5.447121828592839, "Weight decreased": 2.23806171613736, "White blood cell count decreased": 3.4219360000256294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/119.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/119.json
index 49e3b9ebd89..33a3d54ecf5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/119.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/119.json
@@ -1 +1 @@
-{"Alanine aminotransferase abnormal ": 6.434005170611481, "Alanine aminotransferase increased ": 3.931382417908347, "Alopecia ": 11.539627893494584, "Alopecia areata ": 3.5621348590715063, "Anal incontinence ": 4.84851190289544, "Back disorder ": 2.953012411180084, "Balance disorder ": 8.004615797996953, "Band sensation ": 23.603536722744007, "Bladder disorder ": 17.78301195745669, "Bladder dysfunction ": 10.47895268023601, "Blood test abnormal ": 2.0227607119696995, "Blood thyroid stimulating hormone decreased ": 2.159968391679767, "Breast cancer female ": 3.651024346219854, "Burning sensation ": 2.3988901542729595, "Carpal tunnel syndrome ": 6.677327134410737, "Central nervous system lesion ": 17.91193502284671, "Cerebral disorder ": 2.4298664088616526, "Cholecystectomy ": 2.411383413191732, "Cognitive disorder ": 3.965358167748715, "Colitis microscopic ": 6.425893920031054, "Condition aggravated ": 3.0025560565901914, "Coronavirus infection ": 2.1517227683798947, "Cystitis ": 2.9962759260341665, "Decreased interest ": 25.25274765279286, "Decubitus ulcer ": 2.850668275872124, "Defaecation urgency ": 2.6236180128357205, "Demyelination ": 3.1058833407848643, "Dental caries ": 3.2887287314432165, "Depressed mood ": 3.7679125976158434, "Depression ": 3.0684068449610264, "Diarrhoea ": 2.180190942105717, "Diffuse alopecia ": 4.697011644250706, "Diplopia ": 2.2924493911566435, "Dysaesthesia ": 2.122148773838767, "Dysgraphia ": 2.5226936651410585, "Dysstasia ": 2.5927521288519326, "Electric shock sensation ": 2.569716159838083, "Expanded disability status scale score increased ": 40.46008890025083, "Exposure during pregnancy ": 2.293976816732774, "Fall ": 4.823870448717509, "Fine motor skill dysfunction ": 2.5246558499671745, "Foot operation ": 2.941000834240202, "Frequent bowel movements ": 2.241297862085012, "Frustration tolerance decreased ": 2.3564022222904524, "Functional gastrointestinal disorder ": 3.326735835569292, "Furuncle ": 2.50425359465408, "Gait disturbance ": 5.305405366597203, "Gait inability ": 2.939628766244774, "Gamma-glutamyltransferase increased ": 3.847512088108151, "Gastrointestinal disorder ": 2.7487596924825333, "Grip strength decreased ": 3.806296054913129, "Hair growth abnormal ": 2.037738115535753, "Hair texture abnormal ": 7.692317511429761, "Head injury ": 2.1150458665514336, "Hemiparesis ": 4.847130669815748, "Hepatic enzyme abnormal ": 3.6084806801509264, "Hepatic enzyme increased ": 3.8048579325186687, "Hospice care ": 3.542406764902814, "Hospitalisation ": 4.616746061367772, "Hypoaesthesia ": 4.97711467130966, "Hypogammaglobulinaemia ": 2.188316885354747, "Hyporeflexia ": 3.759038421945805, "Hysterectomy ": 5.032185795308699, "Immunosuppression ": 2.57865466571082, "Impaired driving ability ": 2.8176228730461337, "Impaired quality of life ": 3.102638900809175, "Incontinence ": 4.979825168622008, "Intervertebral disc protrusion ": 3.798083180373204, "JC polyomavirus test positive ": 93.99684932207109, "JC virus infection ": 7.22793913717343, "Joint injury ": 2.296500462126027, "Kidney infection ": 3.4070374682710747, "Lhermitte's sign ": 38.2030645950247, "Liver function test increased ": 4.520380219892439, "Loss of personal independence in daily activities ": 2.9568122256442715, "Lung adenocarcinoma ": 2.9313062166725308, "Lymphocyte count abnormal ": 11.750472849913418, "Lymphocyte count decreased ": 9.07767323526001, "Lymphocyte count increased ": 3.820953428674964, "Lymphopenia ": 12.88293630942308, "Madarosis ": 9.249042440884208, "Magnetic resonance imaging abnormal ": 33.06925983358782, "Memory impairment ": 3.971943006931743, "Mental impairment ": 2.142678966032652, "Micturition urgency ": 4.443833465903453, "Mobility decreased ": 5.583674539688123, "Monocyte count increased ": 4.333626423606355, "Motor dysfunction ": 2.0892280592953254, "Movement disorder ": 3.12683396339216, "Multiple sclerosis ": 143.1144337118876, "Multiple sclerosis pseudo relapse ": 37.02130013216005, "Multiple sclerosis relapse ": 442.6417017384261, "Muscle spasticity ": 11.406813967845356, "Muscular weakness ": 3.0129145779896995, "Musculoskeletal disorder ": 4.455088440664124, "Nail disorder ": 3.785382125654896, "Nephrolithiasis ": 2.6480799065970544, "Nerve compression ": 2.472623960927029, "Neuralgia ": 2.1971677395686915, "Neurogenic bladder ": 4.33717106904458, "Neuropathy peripheral ": 4.487300820182091, "Onychoclasis ": 6.33619214659702, "Onychomadesis ": 4.585422856277496, "Optic neuritis ": 16.36978572389746, "Ovarian cancer ": 2.058107883122748, "Paraesthesia ": 3.2045524005492, "Paraparesis ": 4.2561447722440535, "Peroneal nerve palsy ": 8.346193704912755, "Pollakiuria ": 2.0063858697199, "Polyneuropathy ": 6.220133233396325, "Product dose omission in error ": 16.149579734186496, "Product dose omission issue ": 5.377298357956642, "Progressive multiple sclerosis ": 96.75645972030392, "Pustular psoriasis ": 2.4676521414628523, "Relapsing-remitting multiple sclerosis ": 37.12850789875517, "SARS-CoV-2 test positive ": 2.7405188461138046, "Sciatica ": 3.407316723784616, "Secondary progressive multiple sclerosis ": 89.49016462666093, "Sensory disturbance ": 4.235154490814195, "Sensory loss ": 3.4799697851754465, "Sexual dysfunction ": 2.360359871291432, "Speech disorder ": 2.2905091293660647, "Spinal disorder ": 3.063876606651061, "Spinal operation ": 9.62756665276687, "Stress ": 4.011606811415761, "Surgery ": 3.3721161132694637, "Temperature intolerance ": 4.28999643454293, "Throat clearing ": 3.194567995316621, "Tooth abscess ": 4.924505224959719, "Tooth infection ": 3.0701381657271045, "Toothache ": 2.6240898219093376, "Transaminases increased ": 2.842578766578991, "Trigeminal neuralgia ": 5.026025127907129, "Unevaluable event ": 9.92809357359207, "Urinary incontinence ": 4.48580835101655, "Urinary tract infection ": 4.492574394020573, "Visual impairment ": 2.446971027120906, "Vitamin D decreased ": 2.46930631740422, "Walking aid user ": 28.62201317376707, "Weight decreased ": 2.1566624206184857, "Wheelchair user ": 8.835778045538053}
\ No newline at end of file
+{"Acute pulmonary oedema": 60.59716447575847, "Anaemia neonatal": 364.09945230536647, "Bronchopulmonary dysplasia": 287.70864136046146, "Congenital arterial malformation": 1355.953495327631, "Delivery": 3975.062946982816, "Exposure during pregnancy": 12.760720574698691, "Foetal exposure during pregnancy": 50.82404342107393, "Foetal growth abnormality": 2117.559489195261, "Hyperbilirubinaemia": 11.585104554602909, "Low birth weight baby": 51.716120868502806, "Maternal exposure during pregnancy": 68.47129950844143, "Neonatal hypocalcaemia": 1996.5794647630812, "Neonatal respiratory distress syndrome": 108.29782339958244, "Normal labour": 168024.3977411458, "Oxygen saturation decreased": 4.236854980231739, "Premature baby": 146.91602308270248, "Premature delivery": 631.9486856443345, "Premature rupture of membranes": 124.85658155349412, "Product use in unapproved indication": 27.21188472333624, "Pulmonary oedema": 4.591047642145907, "Respiratory distress": 9.197036250336888, "Stillbirth": 98.94594387338395, "Superficial vein thrombosis": 41.86480049884824, "Tachypnoea": 15.338794969603104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1190.json
index 4061aa7e582..da402ed43cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1190.json
@@ -1 +1 @@
-{"Hyponatraemia ": 71.49573461877132}
\ No newline at end of file
+{"Abortion spontaneous": 4.235924985411844, "Allergy to animal": 5.336252706063613, "Anaphylactic reaction": 12.053614301991722, "Anaphylactoid reaction": 3.496956817012715, "Angioedema": 4.969808796998703, "Antinuclear antibody positive": 2.757847378933025, "Aphonia": 3.0061926110009853, "Asthma": 17.399260804877425, "Asthmatic crisis": 15.189563851014636, "Atypical pneumonia": 3.3041485295367634, "Blood immunoglobulin E abnormal": 110.40345288820612, "Blood immunoglobulin E decreased": 73.89204220973382, "Blood immunoglobulin E increased": 51.41391733544492, "Blood immunoglobulin G decreased": 4.002424426005726, "Blood pressure diastolic decreased": 2.381075546271854, "Blood pressure systolic increased": 2.830253663699947, "Body temperature decreased": 2.679584000995417, "Breast cancer": 3.7785167452857, "Breast conserving surgery": 6.142662017505936, "Breast mass": 3.008872779811941, "Breast neoplasm": 7.519044519746774, "Breath sounds abnormal": 5.307364265968516, "Bronchial secretion retention": 3.392692037356375, "Bronchiectasis": 2.431348778599655, "Bronchitis": 5.294202827290986, "Bronchitis chronic": 3.5212798120886037, "Bronchopulmonary aspergillosis allergic": 7.645767157499886, "Bronchospasm": 6.079094022198634, "Chest discomfort": 4.4193358355067165, "Choking": 2.697133503589303, "Choking sensation": 2.782763696931359, "Chronic obstructive pulmonary disease": 2.6170288884405863, "Chronic spontaneous urticaria": 90.44937830054408, "Circumoral oedema": 7.747470057477846, "Colon cancer": 2.895647900133583, "Computerised tomogram abnormal": 5.262822873659927, "Concomitant disease aggravated": 3.315331822590602, "Coronavirus infection": 2.790707510922037, "Cough": 3.363233825923252, "Cystic fibrosis": 3.899683002506681, "Dermatitis atopic": 6.10030137690918, "Diffuse alopecia": 2.6869496960160277, "Dysphonia": 2.6851119115028546, "Dyspnoea": 2.930193413261251, "Dyspnoea exertional": 2.1145989537354444, "Ear infection": 3.040112373374012, "Ear swelling": 2.5926258146026218, "Enlarged uvula": 6.504797389452493, "Eosinophil count increased": 5.476101458511203, "Eosinophilic granulomatosis with polyangiitis": 16.741397252534668, "Eosinophilic oesophagitis": 6.299321516974139, "Eye oedema": 3.103130538697072, "Eye pruritus": 4.486953457092273, "Eye swelling": 2.607784550082871, "FEV1/FVC ratio decreased": 74.0900143252954, "Flushing": 3.7167230737031383, "Food allergy": 4.486514102666203, "Forced expiratory volume decreased": 29.310949396213665, "Frustration tolerance decreased": 3.0572908959121645, "Gastroenteritis viral": 2.138554759247791, "Heart rate increased": 2.371493000048711, "Human anti-human antibody test": 156.16425587215184, "Hypersensitivity": 3.334261641298798, "Hyperventilation": 4.153475508116762, "Hypoventilation": 9.901946952078251, "Idiopathic urticaria": 24.82710464781455, "Incorrect route of product administration": 3.1794267996872017, "Increased upper airway secretion": 2.716521190795712, "Infection 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3.8061345723664624, "Middle insomnia": 3.682727916880797, "Mouth swelling": 2.278699143611436, "Nasal congestion": 4.818888881202088, "Nasal polyps": 5.865389581311857, "Nasopharyngitis": 3.5087013986206883, "Needle issue": 6.233384332184372, "Neutrophil count increased": 2.5332110599457502, "Normal newborn": 14.595419058219372, "Obstructive airways disorder": 5.655817256685253, "Oesophageal spasm": 5.055931464545518, "Oropharyngeal pain": 2.134960302884575, "Oropharyngeal swelling": 5.334275528398657, "Paranasal sinus discomfort": 2.3568381766486555, "Peak expiratory flow rate decreased": 39.524262476685344, "Pharyngeal disorder": 4.549457264915034, "Pharyngeal oedema": 2.791571589983282, "Pharyngeal swelling": 5.751740422515013, "Pharyngitis": 2.451456662646564, "Pharyngitis streptococcal": 2.425971990554596, "Pigmentation disorder": 2.2232093522323515, "Pleural rub": 121.40023571606756, "Pneumonia": 2.557268297172824, "Polyp": 2.047137667216888, "Postoperative wound infection": 2.118523083237267, "Product supply issue": 2.5835795722786825, "Productive cough": 7.555071575066395, "Pruritus": 2.642148559333093, "Pulmonary congestion": 6.035381876711719, "Pulmonary function test decreased": 11.295100128559682, "Pulmonary mass": 3.007078089172426, "Rales": 2.939297022574942, "Respiratory disorder": 3.409257585453896, "Respiratory distress": 2.2562026105387103, "Respiratory rate increased": 5.157380116918331, "Respiratory tract congestion": 11.02649695039315, "Respiratory tract infection": 4.308261556089283, "Rhinitis": 2.456566342968939, "Rhinorrhoea": 2.344692654500089, "Rhonchi": 9.19097870107115, "Rubber sensitivity": 7.043352307243448, "Scratch": 4.281244513369621, "Seasonal allergy": 4.112645436382335, "Secretion discharge": 4.859287380261092, "Sensation of foreign body": 3.1418626587713843, "Sensitivity to weather change": 6.485839434529864, "Serum sickness": 25.031819764707457, "Serum sickness-like reaction": 10.77172523023931, "Sinus congestion": 7.812264648315513, "Sinus disorder": 4.006661407798301, "Sinus operation": 7.436710230346999, "Sinusitis": 4.743780779947715, "Skin infection": 3.342033417534267, "Skin lesion": 2.280642946835563, "Skin oedema": 5.874135795690657, "Skin plaque": 4.687672818951868, "Skin sensitisation": 7.046871761810538, "Skin swelling": 3.0656877192478333, "Sneezing": 4.156687875883475, "Spirometry abnormal": 9.540569282855714, "Sputum discoloured": 16.468371354490174, "Sputum increased": 2.3035979674062435, "Sputum retention": 4.97966480795533, "Stillbirth": 2.539588048741906, "Streptococcal infection": 2.333086403524534, "Stress": 2.065344037271125, "Stridor": 5.414520676846805, "Suffocation feeling": 2.384472788429843, "Swelling face": 3.153603937995646, "Swelling of eyelid": 2.02944239045929, "Swollen tongue": 3.8450131494927584, "Symptom recurrence": 3.3462164605735776, "Syringe issue": 4.5638630696758895, "Temperature intolerance": 2.987774435861719, "Throat clearing": 7.0406736085255845, "Throat irritation": 4.394188159004771, "Throat tightness": 7.456707910602027, "Thyroid cancer": 2.2299419951494794, "Tongue disorder": 2.40085035171356, "Type I hypersensitivity": 4.032933074165289, "Type III immune complex mediated reaction": 9.123314363409628, "Upper airway obstruction": 19.60295950321052, "Upper limb fracture": 2.070160168182349, "Upper respiratory tract congestion": 4.333657040116179, "Upper respiratory tract infection": 3.282196683747181, "Upper-airway cough syndrome": 4.361711039263777, "Urticaria": 6.429978739271183, "Urticaria chronic": 3.624366755925291, "Urticarial vasculitis": 13.52977861737449, "Viral infection": 4.297590070120743, "Weight increased": 2.3426226883093952, "Wheezing": 12.403572838047836, "White blood cell count increased": 2.229459881079572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1191.json
index d1986f02d63..bd2888e6ca9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1191.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.6997288950118885, "Adverse drug reaction ": 9.046900481954678, "Blood pressure increased ": 4.591996010431943, "Carbohydrate antigen 125 increased ": 285.5785119182075, "Constipation ": 5.6273115538596725, "Drug hypersensitivity ": 3.091774643868139, "Dry mouth ": 3.2620418374035376, "Dyspepsia ": 2.361983253494369, "Flatulence ": 5.670689525681608, "Haemoglobin decreased ": 5.6470189749710045, "Heart rate increased ": 4.688671924695227, "Illness ": 3.566532500852188, "Insomnia ": 2.8234805089933075, "Neuropathy peripheral ": 9.58059667034042, "Platelet count decreased ": 6.030893997856028, "Product dose omission in error ": 37.735137892659885, "Product dose omission issue ": 5.875875550405029, "Sleep disorder ": 2.6855933521846715, "Taste disorder ": 4.73597570467942}
\ No newline at end of file
+{"Amnesia": 2.4786911840725074, "Aortic dissection": 2.5107483294547484, "Asthenia": 2.446358667821771, "Back pain": 2.982876412686557, "Balance disorder": 2.409506461859013, "Bedridden": 2.6162967607047487, "Bladder disorder": 2.411278278563966, "Blood urine present": 10.157948898610009, "Bone cancer": 19.7788821453022, "Bone lesion": 3.5066149558470143, "Bone pain": 3.758905539395671, "Cancer pain": 19.53471988627772, "Cerebrovascular accident": 2.005636503571277, "Choking": 3.0075903289379786, "Cognitive disorder": 3.513692213241961, "Compression fracture": 4.798983212938757, "Constipation": 3.232921755092056, "Cystitis": 2.7696308003593666, "Death": 11.995366495415595, "Decreased appetite": 5.03868802931042, "Decreased interest": 3.500845114834425, "Dehydration": 2.1052464488871245, "Dementia": 4.215567406105599, "Dementia Alzheimer's type": 2.241627140416161, "Dysphagia": 6.667219705365622, "Dysstasia": 2.023859496255933, "Eating disorder": 2.564511658533738, "Faeces hard": 2.7048557744654835, "Failure to thrive": 4.361504152245531, "Fall": 4.226960969710412, "Feeding disorder": 2.511557472977726, "Femur fracture": 2.133065772637197, "Foreign body in throat": 23.56750391630196, "Fracture": 2.0313533656356904, "Full blood count decreased": 3.4862464490880787, "Gait disturbance": 2.061197074708419, "Gait inability": 2.4856700675003744, "General physical health deterioration": 2.547642216100543, "Gynaecomastia": 2.51981684479072, "Haematuria": 2.0918382320871345, "Haemorrhage urinary tract": 7.8092025705464865, "Head injury": 2.023987785892876, "Hip fracture": 3.95226414268878, "Hormone-refractory prostate cancer": 10.83061766443097, "Hospice care": 9.104758627401148, "Hospitalisation": 7.95369580394521, "Hot flush": 9.873220279739709, "Hydronephrosis": 3.5142821980481207, "Hypersomnia": 3.345165253333059, "Hypogeusia": 2.106872608271572, "Illness": 2.0692474149456146, "Incontinence": 2.3260090743721022, "Intentional dose omission": 11.041481994955625, "Intentional underdose": 17.542703145611828, "International normalised ratio decreased": 2.6843084356349656, "Kidney infection": 2.464779679548623, "Malignant neoplasm progression": 33.76219057946895, "Memory impairment": 3.0024892426353595, "Metastases to bone": 9.678539324149195, "Metastases to central nervous system": 2.042302060067424, "Metastases to spine": 5.766791176801762, "Metastasis": 6.664261700612534, "Metastatic neoplasm": 2.5766044654416627, "Muscular weakness": 2.495394483175778, "Neoplasm": 2.78309094623456, "Nocturia": 4.564941828923853, "Oncologic complication": 17.07118321948716, "Pathological fracture": 2.305351023381109, "Performance status decreased": 2.2526829574376426, "Peripheral swelling": 2.492510051591361, "Physical deconditioning": 2.315673831297754, "Pneumonia aspiration": 2.079228066426385, "Pollakiuria": 3.2310860258787715, "Posterior reversible encephalopathy syndrome": 5.153549072430196, "Prescribed underdose": 15.400983405917302, "Product availability issue": 2.802395357476865, "Product dose omission issue": 3.5060257632232683, "Product physical issue": 2.810342116830472, "Product size issue": 157.7860447798756, "Product use complaint": 14.154089949971391, "Prostate cancer": 10.816870647420302, "Prostate cancer metastatic": 23.287040880013382, "Prostate cancer recurrent": 16.770769596990146, "Prostatic specific antigen abnormal": 105.7858051350146, "Prostatic specific antigen increased": 236.49024028387117, "Regurgitation": 2.222294789879967, "Restless legs syndrome": 5.586587972308941, "Rib fracture": 2.897442286644785, "Seizure": 2.360950347388388, "Shoulder fracture": 3.944255454997076, "Sinus disorder": 2.6194753839403355, "Spinal compression fracture": 3.104267528445399, "Spinal cord compression": 10.221922409564849, "Spinal cord neoplasm": 16.244264038495704, "Spinal operation": 2.4496477590400207, "Stent placement": 4.0106960763241775, "Taste disorder": 3.697972778776074, "Terminal state": 13.890725342976491, "Throat cancer": 2.4759666002173493, "Tooth extraction": 2.065093327589126, "Treatment noncompliance": 5.955133806365104, "Underdose": 33.0552666161666, "Upper limb fracture": 3.156395475389211, "Ureteric obstruction": 7.205096110626176, "Urinary bladder haemorrhage": 6.414623725004774, "Urinary incontinence": 2.1573132057832267, "Urinary tract disorder": 2.7969391403258377, "Urinary tract infection": 3.265964861724747, "Urinary tract obstruction": 5.677076881147115, "Vascular graft": 4.104576591490448, "Walking aid user": 2.140420282989459, "Walking disability": 2.150272596352453, "Weight decreased": 3.365319771544744, "Wrong technique in product usage process": 2.234417457183803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1192.json
index f43557e92d4..12a669f32c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1192.json
@@ -1 +1 @@
-{"Acne ": 5.960635758626046, "Actinic keratosis ": 25.578306046276357, "Alopecia ": 4.494522325699221, "Arthralgia ": 2.534101627650563, "Basal cell carcinoma ": 9.46161612810584, "Blister ": 2.6675400667231437, "Blood bilirubin increased ": 3.5236908294593285, "Brain neoplasm ": 10.077720484121896, "Cholestasis ": 2.540538814595917, "Conjunctivitis ": 4.289907678071463, "Death ": 5.927415486900074, "Decreased appetite ": 2.972018384244621, "Dermatitis ": 2.22722579073258, "Dermatitis acneiform ": 8.024928535082667, "Dermatitis bullous ": 4.259977937268271, "Dermatitis exfoliative generalised ": 9.615550492607357, "Disease progression ": 9.158677438627237, "Drug reaction with eosinophilia and systemic symptoms ": 6.590325407977982, "Dry skin ": 7.936653768709182, "Dysgeusia ": 2.6864448286956706, "Dysphagia ": 3.2535979407698523, "Electrocardiogram QT prolonged ": 6.043463166343853, "Eosinophilia ": 5.716945552966066, "Erythema ": 3.981335004800109, "Face oedema ": 3.707722710651326, "Gamma-glutamyltransferase increased ": 2.8100449585369094, "Hepatic cytolysis ": 2.458740477873069, "Hepatotoxicity ": 4.519386010526862, "Hyperbilirubinaemia ": 2.8194306687265214, "Hyperkeratosis ": 75.66767677058583, "Intentional product use issue ": 6.163320274795139, "Iridocyclitis ": 18.59357782861868, "Keratoacanthoma ": 699.656364211994, "Keratosis pilaris ": 657.729500189497, "Liver function test increased ": 3.3542046490974595, "Lymphopenia ": 2.933488122200715, "Malignant melanoma ": 22.42615015582018, "Mass ": 21.7387670768274, "Melanocytic naevus ": 61.79864680335034, "Metastases to central nervous system ": 38.98943047378976, "Metastases to lung ": 3.695946709795381, "Metastasis ": 13.484747460593926, "Metastatic malignant melanoma ": 51.46286329880186, "Mucosal inflammation ": 2.962792836266497, "Neoplasm ": 32.394735538409606, "Ocular hyperaemia ": 2.432905770960995, "Palmar-plantar erythrodysaesthesia syndrome ": 5.183406312968176, "Palmoplantar keratoderma ": 167.49371806436864, "Panniculitis ": 17.593938575093958, "Pericardial effusion ": 3.235146468661178, "Photosensitivity reaction ": 57.499578519567216, "Rash ": 5.329948129045221, "Rash erythematous ": 2.127004733926385, "Rash maculo-papular ": 6.218726989298431, "Rash papular ": 2.3311874212651387, "Rash pustular ": 6.526124254759968, "Skin cancer ": 5.579448324591023, "Skin disorder ": 2.3144270772876645, "Skin exfoliation ": 4.663787839091613, "Skin lesion ": 4.029432384047933, "Skin mass ": 6.387952162329265, "Skin papilloma ": 210.90135374181688, "Skin reaction ": 4.691425979020631, "Skin toxicity ": 30.54139831812801, "Squamous cell carcinoma ": 113.2547770819626, "Squamous cell carcinoma of skin ": 69.61553247999973, "Stevens-Johnson syndrome ": 3.0037555079773863, "Sunburn ": 163.6866523612104, "Taste disorder ": 2.7497857124415304, "Toxic epidermal necrolysis ": 5.085962498058287, "Toxic skin eruption ": 5.339208258861574, "Uveitis ": 14.33562206950657, "Weight decreased ": 2.0381982913901044}
\ No newline at end of file
+{"Abnormal behaviour": 2.562222455144273, "Abnormal dreams": 8.91516435096831, "Abnormal sleep-related event": 109.88972220291755, "Adverse drug reaction": 2.341548170670347, "Agitation": 4.6827162084615965, "Amnesia": 2.1995343898763675, "Anger": 2.2570229130518658, "Anxiety": 4.678931396658194, "Apnoea": 3.7164870615315473, "Arthritis": 2.431628755455323, "Back disorder": 8.387743550887034, "Bipolar disorder": 6.017577541938056, "Blood potassium decreased": 5.348963562480917, "Blood pressure increased": 2.878320315465713, "Blood sodium decreased": 2.5091136657630977, "Brain fog": 2.345878159167349, "Breath holding": 93.9842839999692, "Bronchitis": 2.7452606514671865, "Cataplexy": 480.4490485530634, "Coma": 2.4178254001898605, "Conduction disorder": 21.35360636598173, "Delusion": 5.735166811737682, "Depressed level of consciousness": 5.4372118707299295, "Depression": 5.542094687141068, "Drug abuse": 2.331073061463816, "Drug hypersensitivity": 3.960839652326516, "Drug screen positive": 26.8361402461562, "Drug withdrawal syndrome": 2.070564829784533, "Dry eye": 2.591655121507472, "Electrolyte imbalance": 7.033362324740189, "Enuresis": 55.01823440148234, "Eye haemorrhage": 3.0555226287267105, "Fall": 2.9975173723957, "Feeling abnormal": 4.958231474384605, "Feeling drunk": 9.496381190061712, "Feeling jittery": 23.63650974650078, "Fibromyalgia": 6.786034529679121, "Foot fracture": 2.2089337026026463, "Gastritis": 2.142776586231483, "Hallucination": 3.638520376701773, "Hangover": 15.869527954881004, "Head injury": 2.781333811644462, "Heart rate decreased": 2.018743809974245, "Hunger": 7.412476807352304, "Hypertension": 2.9746266979896983, "Initial insomnia": 12.422226735229687, "Insomnia": 2.416921029873992, "Intentional product misuse": 3.5747610497699687, "Intentional product use issue": 3.297483072452432, "Intervertebral disc degeneration": 5.197283268681771, "Intervertebral disc protrusion": 7.969155623542485, "Irritability": 4.2590883169872695, "Joint dislocation": 5.122601361281031, "Joint injury": 4.204518378548572, "Lethargy": 3.511171568626322, "Limb injury": 3.89101592731847, "Mania": 3.17662604767393, "Memory impairment": 3.484801502040036, "Migraine": 2.75245547697651, "Mood altered": 2.380997367637278, "Muscle tightness": 6.2617087744399615, "Narcolepsy": 48.93970589237109, "Nephrolithiasis": 3.267825580540081, "Nervousness": 5.17106940957871, "Neuralgia": 2.436432241168069, "Nightmare": 2.909004273096369, "Obsessive-compulsive disorder": 5.763962290003075, "Obstructive sleep apnoea syndrome": 22.398941260294063, "Overdose": 2.421502865789863, "Panic attack": 5.907251742015056, "Paranoia": 9.683113198735764, "Parasomnia": 102.17006879388096, "Pollakiuria": 3.122479395364816, "Poor quality sleep": 3.1288373834274723, "Pre-existing condition improved": 18.91428706978631, "Psychomotor hyperactivity": 3.042325868507257, "Psychotic disorder": 5.2358790165350255, "Respiratory depression": 8.265027129324123, "Restless legs syndrome": 4.735675121532666, "Road traffic accident": 4.025683305634043, "Sedation": 4.006303483220632, "Sinusitis": 3.5627476951660317, "Skin laceration": 4.640391406402893, "Sleep apnoea syndrome": 24.397330689746223, "Sleep paralysis": 44.54866766080696, "Sleep terror": 16.091386182075908, "Sleep-related eating disorder": 401.28825518090326, "Snoring": 19.3089756108348, "Somnambulism": 52.219381996692576, "Somnolence": 4.256544353004254, "Stress": 6.489671831261996, "Suicidal ideation": 5.22832178953762, "Suicide attempt": 5.339331875882588, "Therapeutic response unexpected": 13.325031925648712, "Thinking abnormal": 3.0482230245428847, "Tooth disorder": 5.840999857338879, "Tremor": 2.796774550799063, "Unevaluable event": 17.527563031262044, "Weight decreased": 5.238743742022834, "Weight increased": 2.19969086193454, "Wrong technique in product usage process": 2.882598558017876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1193.json
index 03bf393c07f..d791b22684c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1193.json
@@ -1 +1 @@
-{"Adverse event ": 21.46923532415132, "Alanine aminotransferase increased ": 2.894299571840142, "Alopecia ": 2.481650002487497, "Ascites ": 5.837390909391751, "Aspartate aminotransferase increased ": 2.0025941408951837, "Blood bilirubin increased ": 3.230507347985777, "Depression ": 2.4235263320194136, "Dyspepsia ": 2.0425352548633824, "Dysphagia ": 2.359828298224959, "Hepatic cirrhosis ": 12.134097510682, "Hepatitis C ": 53.639794945656256, "Hypertransaminasaemia ": 11.505857133645623, "Insomnia ": 2.221148345960796, "Irritability ": 2.3672451513448864, "Product dose omission issue ": 6.760180780468845, "Transaminases increased ": 4.710252917028419, "Treatment failure ": 10.099577573633452, "Virologic failure ": 84.34085865790985}
\ No newline at end of file
+{"Adrenal disorder": 21.74454274747636, "Adrenal insufficiency": 20.863380297241548, "Adrenocortical insufficiency acute": 21.3103035724141, "Adverse event": 5.021723104558758, "Autoimmune colitis": 250.55159493718256, "Autoimmune hepatitis": 27.81665257726338, "Blood sodium decreased": 2.480488946750292, "Blood thyroid stimulating hormone decreased": 15.645556184679588, "Colitis": 106.40084007570152, "Colitis ulcerative": 4.756232395930666, "Conjunctivitis": 3.0194215175323427, "Death": 7.314046515584372, "Dehydration": 2.942321034289449, "Dermatitis": 2.7726360201119946, "Diarrhoea": 5.713554974343367, "Diarrhoea haemorrhagic": 7.462390705172848, "Encephalitis": 3.6112130804300513, "Endocrine disorder": 46.589106690286464, "Enteritis": 6.830994180042691, "Enterocolitis": 80.62849752865445, "Enterocolitis haemorrhagic": 37.19148447662393, "General physical health deterioration": 2.561426451371126, "Guillain-Barre syndrome": 4.97783944956507, "Hepatic cytolysis": 3.0311805394802147, "Hepatic failure": 4.671356820221756, "Hepatitis": 8.581449838269881, "Hepatotoxicity": 6.895680990131609, "Hospitalisation": 2.899782529060089, "Hyperthyroidism": 3.931229555385353, "Hypertransaminasaemia": 6.916256578616816, "Hypophysitis": 349.16454064114987, "Hypopituitarism": 131.1982648591851, "Hypothalamo-pituitary disorder": 56.0289313002347, "Hypothyroidism": 5.031543586318606, "Immune-mediated enterocolitis": 9.312142354077356, "Intentional product use issue": 3.471437852717989, "Intestinal perforation": 62.87074018415184, "Large intestine perforation": 33.74146528597284, "Liver disorder": 2.1825646687641305, "Liver function test increased": 3.66705152791576, "Lymphocytic hypophysitis": 83.95034300033848, "Malignant melanoma": 2.4404107321332678, "Malignant neoplasm progression": 52.809348812424254, "Meningitis": 6.01690293636279, "Metastases to central nervous system": 44.140995296166736, "Metastases to liver": 3.2572757699936377, "Metastases to lung": 6.801163194434338, "Metastasis": 6.750475518621078, "Neoplasm": 5.372987939217346, "Neuropathy peripheral": 2.409681153891275, "Peritonitis": 6.7155303973396485, "Pleural effusion": 2.1791364988046147, "Pneumonitis": 7.427405654605455, "Prescribed overdose": 32.797987113559344, "Sepsis": 2.089961680948217, "Thyroid disorder": 6.7735081084961655, "Thyroiditis": 6.955764566201648, "Uveitis": 5.682803675190282, "Vitiligo": 30.315521759509934, "Weight decreased": 2.176922518401426}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1194.json
index 66852593af0..f9b891be6dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1194.json
@@ -1 +1 @@
-{"Leukopenia ": 55.47428453801862, "Lymphopenia ": 343.82570308638475, "Neutropenia ": 27.22585115951664}
\ No newline at end of file
+{"Acute myeloid leukaemia": 3.5334053952819207, "Agitation": 2.888920676884368, "Alanine aminotransferase abnormal": 29.440642694940514, "Aphasia": 13.94436212972964, "Aspartate aminotransferase increased": 2.367820508889373, "Aspergillus infection": 5.149610333616589, "B-cell aplasia": 105.01606126652784, "B-cell lymphoma": 25.700012548907285, "Bacteraemia": 8.802988200883284, "Bone marrow failure": 12.491171229720694, "Bradykinesia": 15.289778675334308, "Bradyphrenia": 17.15757591743116, "Brain oedema": 8.70466275827124, "Clostridium difficile colitis": 2.965516752817785, "Clostridium difficile infection": 3.146396404017156, "Coagulopathy": 2.284966711588554, "Confusional state": 3.431549087613782, "Cytokine release syndrome": 1132.215433833366, "Cytokine storm": 113.96681113744314, "Cytomegalovirus infection reactivation": 8.17698841467584, "Cytopenia": 31.30585050198848, "Death": 3.5292376209164846, "Depressed level of consciousness": 2.747902572659217, "Diffuse large B-cell lymphoma": 88.44877055912738, "Diffuse large B-cell lymphoma recurrent": 37.29693213465015, "Disease progression": 15.335334935028651, "Disease recurrence": 5.695378780197661, "Disorientation": 4.217527845458372, "Disseminated intravascular coagulation": 3.3469378820965554, "Dysgraphia": 49.00119438871456, "Encephalopathy": 27.64547330737424, "Febrile neutropenia": 6.44990512549063, "Haemophagocytic lymphohistiocytosis": 29.78905983703002, "Hyperbilirubinaemia": 3.793739634463942, "Hypertransaminasaemia": 4.145280065610461, "Hypervolaemia": 4.527191962245125, "Hypoalbuminaemia": 21.912588334117206, "Hypogammaglobulinaemia": 78.53503916656763, "Hypotension": 3.3969764830241678, "Hypoxia": 8.396987476281254, "Immune effector cell-associated neurotoxicity syndrome": 2252.4733315214685, "Incontinence": 13.276346641173468, "Infection": 2.92690775161163, "Lymphoma": 12.77224862846974, "Memory impairment": 2.343798909178276, "Mental status changes": 8.193608969219776, "Multiple organ dysfunction syndrome": 3.287513838781345, "Myelodysplastic syndrome": 5.69639157441125, "Nervous system disorder": 3.036023505601178, "Neurological symptom": 3.932976493530116, "Neurotoxicity": 343.4460247622447, "Neutropenia": 4.726212627884596, "Pancytopenia": 7.294153515095287, "Pleural effusion": 2.4140863193354662, "Primary mediastinal large B-cell lymphoma": 376.71858990274416, "Sepsis": 3.0186360400002594, "Septic shock": 5.950482192849383, "Serum ferritin increased": 9.292896250720664, "Status epilepticus": 2.47426321594554, "Systemic candida": 15.470756552538058, "Tachycardia": 2.236922574400057, "Tachypnoea": 3.256417752883764, "Therapy non-responder": 2.55516218822567, "Therapy partial responder": 3.696353065879283, "Thrombocytopenia": 2.0357649705225485, "Tremor": 2.9957418213089984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1195.json
index c35aaa98bf0..f03013e7028 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1195.json
@@ -1 +1 @@
-{"Blood lactic acid increased ": 53.96786311775678, "Hepatic steatosis ": 22.559685416350383, "Hypoaesthesia ": 2.252591092118696, "Lactic acidosis ": 112.65864287560146, "Lipodystrophy acquired ": 129.77964585708622, "Neuropathy peripheral ": 22.937625527602847, "Pancreatitis ": 22.351247477085668, "Pancreatitis acute ": 21.72216881088159, "Polyneuropathy ": 58.4463593594333, "Pregnancy ": 75.94110485622062, "Weight decreased ": 2.0873281334524787}
\ No newline at end of file
+{"Acute kidney injury": 5.096166118004733, "Alanine aminotransferase increased": 6.042228462807276, "Anaemia": 3.998053285368551, "Aspartate aminotransferase increased": 4.863140768882386, "Blood alkaline phosphatase increased": 7.09801570466784, "Blood bilirubin increased": 4.467904246632971, "Blood creatine phosphokinase increased": 19.163283829621587, "Capillary leak syndrome": 78.05570506736963, "Cardiac failure": 5.490110071418801, "Catheter site erythema": 82.19907633765617, "Cholestasis": 8.78889935741572, "Disease progression": 5.430112799785632, "Extravasation": 219.13372806767552, "Febrile neutropenia": 11.031648660353635, "Gamma-glutamyltransferase increased": 6.669493541020436, "Haematotoxicity": 27.102429169140475, "Hepatic cytolysis": 19.964846515916463, "Hepatic enzyme increased": 3.4749654815084074, "Hepatic failure": 11.40502088599487, "Hepatic function abnormal": 3.702116887134036, "Hepatotoxicity": 19.531439013723443, "Hypertransaminasaemia": 26.536317994353084, "Infusion site extravasation": 170.21029631779604, "Leukopenia": 5.255639249324282, "Multiple organ dysfunction syndrome": 8.030080488581554, "Myelosuppression": 4.890360513337416, "Neutropenia": 14.22844259828898, "Neutropenic sepsis": 40.93582995344361, "Neutrophil count decreased": 3.963931140250513, "Pancytopenia": 21.793830302109644, "Platelet count decreased": 2.8349447596269224, "Pleural effusion": 3.1560213513938526, "Pulmonary embolism": 2.0523336845785307, "Renal failure": 3.931701952138176, "Rhabdomyolysis": 49.58194982393093, "Sarcoma": 123.17448561593534, "Sepsis": 5.464519096291464, "Septic shock": 5.198717897605632, "Thrombocytopenia": 8.657620828406943, "Transaminases increased": 20.57170528979911}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1196.json
index 0b354b25efc..2208f7ea60f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1196.json
@@ -1 +1 @@
-{"Anaemia ": 2.777638455063156, "Hypoaesthesia ": 3.727758363392819, "Leukopenia ": 16.92251773841379, "Myelodysplastic syndrome ": 139.32337300908432, "Myelosuppression ": 8.677926270546802, "Neutropenia ": 31.667806889981456, "Neutrophil count decreased ": 13.626062095132308, "Off label use ": 2.2929224490737914, "Platelet count decreased ": 33.75838731454105, "Thrombocytopenia ": 23.739532794081796, "White blood cell count decreased ": 22.088116770801957}
\ No newline at end of file
+{"Thrombocytopenia": 33.69316520272974}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1197.json
index 8a6971d491b..ddde6746163 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1197.json
@@ -1 +1 @@
-{"Abdominal pain ": 4.138599471559138, "Alanine aminotransferase increased ": 5.377769299481594, "Amylase increased ": 18.37404941793895, "Aspartate aminotransferase increased ": 6.535088991362754, "Blood bilirubin increased ": 2.7379674010269577, "Blood creatine phosphokinase increased ": 5.953186378966396, "Blood creatinine increased ": 2.7379568590437056, "Blood lactate dehydrogenase increased ": 5.124833864366321, "Conjunctivitis ": 9.77045401966187, "Cough ": 2.872819726979358, "Drug hypersensitivity ": 3.369211735638504, "Haematocrit decreased ": 5.334144563589491, "Hypersensitivity ": 11.9867810876284, "Hypotension ": 2.9564950538750723, "Hypoxia ": 5.229033669015095, "Ill-defined disorder ": 4.426544322570443, "Lipase increased ": 11.904355371471253, "Liver function test abnormal ": 4.63103788702584, "Lung infiltration ": 9.54455091703132, "Malaise ": 2.2343565591019785, "Oedema ": 3.284761378562467, "Pancreatitis ": 2.743751463134501, "Pneumocystis jirovecii pneumonia ": 10.561805036617551, "Pyrexia ": 2.447800505976079, "Rash ": 3.090139698558901, "Rash macular ": 4.197702960892846, "Rash maculo-papular ": 9.857993925837802, "Red blood cell count decreased ": 5.033734481746527, "Tachycardia ": 2.931969871553068, "Vomiting ": 2.695546758910138}
\ No newline at end of file
+{"Disease progression": 66.12009232952163, "Pancytopenia": 42.12177304765153}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1198.json
index cfc8ede21e6..52c09a0cf4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1198.json
@@ -1 +1 @@
-{"Anaemia ": 45.80609921184413, "Weight decreased ": 3.842837775259624}
\ No newline at end of file
+{"Intentional overdose": 17.66585940476954, "Somnolence": 6.366210137689635, "Tachycardia": 7.297740790737155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1199.json
index 92e0c1939e5..650ee007302 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1199.json
@@ -1 +1 @@
-{"Drug ineffective ": 5.025902228987543, "Neutropenia ": 14.512016842360689}
\ No newline at end of file
+{"Completed suicide": 83.49165343645447, "Toxicity to various agents": 16.427490773455173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/12.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/12.json
index a56ec0c9ffd..7d9e2c5bb1e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/12.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/12.json
@@ -1 +1 @@
-{"Bone pain ": 22.1530615163487, "Chest pain ": 3.674712311667832, "Neutropenia ": 15.908291807085313, "Therapy non-responder ": 33.217418955752905}
\ No newline at end of file
+{"Deafness": 57.3306409342533, "Disease progression": 55.143023382756525, "Lymphadenopathy": 5.855002439232344, "Mantle cell lymphoma recurrent": 4869.774588526102, "Off label use": 6.14808471445246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/120.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/120.json
index fbab3b5cde5..640c6894f30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/120.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/120.json
@@ -1 +1 @@
-{"Haematotoxicity ": 900.225238050385, "Mucosal inflammation ": 248.2440796808056, "Multiple organ dysfunction syndrome ": 40.39871300762043, "Neutropenia ": 35.42540171394921, "Pyrexia ": 4.059378692465007, "Sepsis ": 51.48045479911119}
\ No newline at end of file
+{"Neutropenia": 26.722796434023117, "Pyrexia": 3.738313506213567}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1200.json
index dabb35cce3b..2247f8edf07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1200.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 5.861718054897056, "Alopecia ": 4.760617450716126, "Aspartate aminotransferase increased ": 5.417595901406393, "Eczema ": 10.35389393301356, "Gamma-glutamyltransferase increased ": 6.332316417040714, "Liver function test increased ": 16.158964072406498, "Multiple sclerosis ": 20.702358230624483, "Multiple sclerosis relapse ": 147.53093478950782, "Psoriasis ": 5.849242037953012, "Rash ": 2.500259020969504, "Urinary tract infection ": 4.419242063856719}
\ No newline at end of file
+{"Asthenia": 2.167416218491582, "Diarrhoea": 7.946907906353174, "Hypertension": 5.394420630969613, "Neuropathy peripheral": 9.422871450826657, "Neutropenia": 12.687501039101878, "Neutrophil count decreased": 13.902036354182746, "Proteinuria": 34.85095200530019, "Thrombocytopenia": 4.171239082190925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1201.json
index 2aebb305209..eb56854248c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1201.json
@@ -1 +1 @@
-{"Clostridium difficile infection ": 798.4585521068532, "Drug ineffective ": 12.315350415126836}
\ No newline at end of file
+{"Nausea": 4.846583821235251, "Respiratory depression": 255.73332124954285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1202.json
index 9622b773946..ab533aab278 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1202.json
@@ -1 +1 @@
-{"Completed suicide ": 51.41570996496304}
\ No newline at end of file
+{"Back pain": 13.621316334841092, "Bone pain": 32.51999598045862, "Chest pain": 2.2365574421603203, "Drug ineffective": 3.4324663213653928, "Erythema": 3.5348986580006336, "Face oedema": 6.011509277355587, "Febrile neutropenia": 11.730560245907713, "Hypotension": 2.153373071213017, "Musculoskeletal chest pain": 11.490152077859197, "Neck pain": 2.236402243869809, "Neutropenia": 9.616960306064634, "Neutrophil count decreased": 2.969683931242883, "Pain": 2.7246176523272485, "Pelvic pain": 25.0254999581374, "Pruritus": 2.475754836813284, "Rash maculo-papular": 7.7295919859914495, "Syncope": 2.1982764490824165, "Therapy non-responder": 5.864661449575679, "Urticaria": 2.557677080224101}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1203.json
index 4a3abcb4469..d7159155aec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1203.json
@@ -1 +1 @@
-{"Exposure during pregnancy ": 46.89507925655583}
\ No newline at end of file
+{"Condition aggravated": 4.862491191696674, "Death": 3.932510598955923, "Diarrhoea": 4.7741977699930365, "Disease progression": 11.499081780696724, "Dysphagia": 9.080036573708147, "Epilepsy": 5.036546526054486, "Gait disturbance": 2.3936751426137324, "Gastrointestinal disorder": 7.548152174015096, "Gastrostomy": 255.98396991124983, "General physical health deterioration": 4.599047971530279, "Neuropathy peripheral": 2.8561952030601345, "Niemann-Pick disease": 73971.8608260369, "Pneumonia": 4.756067784436551, "Pneumonia aspiration": 17.203773895378895, "Respiratory failure": 9.326005181766714, "Seizure": 3.436587217212807, "Sepsis": 2.961553670659813, "Thrombocytopenia": 2.304842525547405, "Tremor": 3.5464772880719093, "Weight decreased": 9.606664910147456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1204.json
index 5804c946a73..684ddf4edd1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1204.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.132787931469786, "Disease progression ": 4.5333313600465255, "Hypercalcaemia ": 39.44529671253941, "Hypocalcaemia ": 65.58578364951654, "Malignant neoplasm progression ": 7.868406437144278, "Metastases to bone ": 29.374429379307216, "Osteonecrosis of jaw ": 390.7119213060007}
\ No newline at end of file
+{"Hyponatraemia": 71.49573461877132}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1205.json
index 5e23c7cd842..ec1fdb4575e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1205.json
@@ -1 +1 @@
-{"Diarrhoea ": 2.788207509449657, "Lactic acidosis ": 61.4950458281488}
\ No newline at end of file
+{"Abdominal distension": 2.654860166814104, "Adverse drug reaction": 8.89652211482779, "Blood pressure increased": 4.515520300608007, "Carbohydrate antigen 125 increased": 280.8305434214498, "Constipation": 5.533673790331035, "Drug hypersensitivity": 3.04037602951367, "Dry mouth": 3.207819856831225, "Dyspepsia": 2.3227307643694206, "Flatulence": 5.575998262318844, "Haemoglobin decreased": 5.553093164833481, "Heart rate increased": 4.610694245274319, "Illness": 3.507237622350069, "Insomnia": 2.7765110740752506, "Neuropathy peripheral": 9.420883734626369, "Platelet count decreased": 5.930549609321306, "Product dose omission in error": 37.10799311838634, "Product dose omission issue": 5.778123986914191, "Sleep disorder": 2.640959552625529, "Taste disorder": 5.273624866344597}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1206.json
index 8f44a639b3e..be5f94d8e9b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1206.json
@@ -1 +1 @@
-{"Abscess ": 13.327878876799396, "Actinomycosis ": 455.2063790686895, "Acute kidney injury ": 3.2780515268582646, "Anaemia ": 2.862494021140573, "Aortic arteriosclerosis ": 55.2295906269168, "Aortic valve incompetence ": 26.34132372946341, "Arteriosclerosis ": 9.835765219158038, "Arthritis ": 2.0453810811446984, "Arthropathy ": 2.430895632992411, "Atelectasis ": 23.739961690060543, "Blood alkaline phosphatase increased ": 2.9294284995589384, "Blood creatinine increased ": 5.489353047981829, "Blood urea increased ": 10.988333564731985, "Bone disorder ": 41.80690296883919, "Bone lesion ": 103.63858104400656, "Bone pain ": 3.57574804264202, "Bone sequestrum ": 1451.4647828344212, "Bronchitis ": 4.231971282776687, "Cardiac failure congestive ": 2.054579128034899, "Cardiomegaly ": 18.884744779447683, "Cataract ": 4.2491718357283785, "Cellulitis ": 2.6517937366580027, "Cholelithiasis ": 5.003313386098775, "Chronic obstructive pulmonary disease ": 4.592053406444897, "Circulatory collapse ": 3.399830281282492, "Compression fracture ": 42.66425174097731, "Deep vein thrombosis ": 2.0029373390952188, "Dehydration ": 2.3289602204786526, "Haematocrit decreased ": 6.303005249763632, "Haemoglobin decreased ": 2.360016145650666, "Hypocalcaemia ": 19.713913298984803, "Hypokalaemia ": 2.356209244741283, "Impaired healing ": 5.11357132893882, "Malignant neoplasm progression ": 5.594598733873204, "Metastases to bone ": 20.61406513089984, "Metastases to liver ": 5.033653834751213, "Osteomyelitis ": 35.10675871764828, "Osteonecrosis ": 5.591603834989503, "Osteonecrosis of jaw ": 194.4531119845519, "Pain in jaw ": 9.804681688608202, "Platelet count decreased ": 2.100403131220224, "Red blood cell count decreased ": 4.146037488744774, "Tooth disorder ": 10.949681459368056, "Tooth extraction ": 91.64366988596448}
\ No newline at end of file
+{"Acne": 5.960635758626046, "Actinic keratosis": 25.578306046276357, "Alopecia": 4.494522325699221, "Arthralgia": 2.534101627650563, "Basal cell carcinoma": 9.46161612810584, "Blister": 2.6675400667231437, "Blood bilirubin increased": 3.5236908294593285, "Brain neoplasm": 10.077720484121896, "Cholestasis": 2.540538814595917, "Conjunctivitis": 4.289907678071463, "Death": 5.927415486900074, "Decreased appetite": 2.971989527805782, "Dermatitis": 2.226934354910742, "Dermatitis acneiform": 8.024928535082667, "Dermatitis bullous": 4.259977937268271, "Dermatitis exfoliative generalised": 9.615550492607357, "Disease progression": 9.158677438627237, "Drug reaction with eosinophilia and systemic symptoms": 6.589780037536045, "Dry skin": 7.936653768709182, "Dysgeusia": 2.6864448286956706, "Dysphagia": 3.2535979407698523, "Electrocardiogram QT prolonged": 6.043463166343853, "Eosinophilia": 5.716945552966066, "Erythema": 3.981296010658975, "Face oedema": 3.707722710651326, "Gamma-glutamyltransferase increased": 2.8100449585369094, "Hepatic cytolysis": 2.458740477873069, "Hepatotoxicity": 4.519386010526862, "Hyperbilirubinaemia": 2.8194306687265214, "Hyperkeratosis": 75.66767677058583, "Intentional product use issue": 6.163320274795139, "Iridocyclitis": 18.59357782861868, "Keratoacanthoma": 690.1300972073765, "Keratosis pilaris": 657.729500189497, "Liver function test increased": 3.3542046490974595, "Lymphopenia": 2.933488122200715, "Malignant melanoma": 22.42615015582018, "Mass": 21.7387670768274, "Melanocytic naevus": 61.79864680335034, "Metastases to central nervous system": 38.98943047378976, "Metastases to lung": 3.695946709795381, "Metastasis": 13.484747460593926, "Metastatic malignant melanoma": 51.46286329880186, "Mucosal inflammation": 2.962792836266497, "Neoplasm": 32.394735538409606, "Ocular hyperaemia": 2.432905770960995, "Palmar-plantar erythrodysaesthesia syndrome": 5.183406312968176, "Palmoplantar keratoderma": 167.49371806436864, "Panniculitis": 17.593938575093958, "Pericardial effusion": 3.235146468661178, "Photosensitivity reaction": 57.499578519567216, "Rash": 5.329874777578041, "Rash erythematous": 2.127004733926385, "Rash maculo-papular": 6.218726989298431, "Rash papular": 2.3309297613093007, "Rash pustular": 6.526124254759968, "Skin cancer": 5.579448324591023, "Skin disorder": 2.3144270772876645, "Skin exfoliation": 4.663787839091613, "Skin lesion": 4.029432384047933, "Skin mass": 6.387952162329265, "Skin papilloma": 210.90135374181688, "Skin reaction": 4.691425979020631, "Skin toxicity": 30.49721068217535, "Squamous cell carcinoma": 113.2547770819626, "Squamous cell carcinoma of skin": 69.61553247999973, "Stevens-Johnson syndrome": 3.0037555079773863, "Sunburn": 163.6866523612104, "Taste disorder": 2.7497857124415304, "Toxic epidermal necrolysis": 5.085962498058287, "Toxic skin eruption": 5.339208258861574, "Uveitis": 14.33562206950657, "Weight decreased": 2.0381982913901044}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1207.json
index 7ba362a546b..641572cacd0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1207.json
@@ -1 +1 @@
-{"Drug interaction ": 9.638167667220303, "Hypersensitivity ": 2.2341482219216244, "Migraine ": 4.0665620084698375, "Seizure ": 8.948579498804962, "Vertigo ": 3.995681524225828, "Weight decreased ": 4.140551471611718, "Weight increased ": 6.5412668695867495}
\ No newline at end of file
+{"Adverse event": 21.46923532415132, "Alanine aminotransferase increased": 2.894299571840142, "Alopecia": 2.481650002487497, "Ascites": 5.837390909391751, "Aspartate aminotransferase increased": 2.0025941408951837, "Blood bilirubin increased": 3.230507347985777, "Depression": 2.4235263320194136, "Dyspepsia": 2.0425352548633824, "Dysphagia": 2.359828298224959, "Hepatic cirrhosis": 12.134097510682, "Hepatitis C": 53.639794945656256, "Hypertransaminasaemia": 11.505857133645623, "Insomnia": 2.221148345960796, "Irritability": 2.3671321153450804, "Product dose omission issue": 6.760180780468845, "Transaminases increased": 4.709964387861108, "Treatment failure": 10.099577573633452, "Virologic failure": 84.34085865790985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1208.json
index ce8f99513e0..dc8f3ef0578 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1208.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 10.15880150495769, "Altered state of consciousness ": 4.500602372188896, "Anuria ": 18.93129004190845, "Bipolar disorder ": 47.7760182561827, "Blood creatine phosphokinase increased ": 3.452511679802398, "Blood urea increased ": 10.683918867731062, "Bradycardia ": 2.557206636240675, "Depressed level of consciousness ": 5.605950268983202, "Drug eruption ": 7.800527925233679, "Drug ineffective ": 4.661092038611515, "Drug intolerance ": 5.296459878887359, "Drug reaction with eosinophilia and systemic symptoms ": 7.466355660520493, "Epilepsy ": 11.425929562407545, "Exposure during pregnancy ": 4.932643594157653, "Foetal exposure during pregnancy ": 2.741425171075988, "Hepatic function abnormal ": 2.6465515709358494, "Leukopenia ": 2.571632092644756, "Mania ": 14.720482474685856, "Migraine ": 4.844660135959851, "Multiple-drug resistance ": 47.622253705920464, "Muscle rigidity ": 14.557648724337986, "Narcolepsy ": 118.88364804682072, "Partial seizures ": 26.277264727374625, "Product quality issue ": 7.581383850589211, "Product use in unapproved indication ": 5.012743940558878, "Psychotic disorder ": 7.525407504306917, "Sedation complication ": 31.296084691284683, "Seizure ": 6.66705369873924, "Somnolence ": 3.321232073056642, "Stevens-Johnson syndrome ": 7.613532078378639, "Substance-induced psychotic disorder ": 120.2758147956934, "Thrombocytopenia ": 2.2046385447999604, "Tonic convulsion ": 106.94908801847065, "Toxicity to various agents ": 2.055609582391482, "Treatment failure ": 5.101233045034793, "Tubulointerstitial nephritis ": 16.623826372446818, "Urinary tract infection ": 3.988565454538741, "Weight increased ": 4.469000600615219, "White blood cell count increased ": 6.168997813084316}
\ No newline at end of file
+{"Leukopenia": 55.4672917215648, "Lymphopenia": 343.82570308638475, "Neutropenia": 27.224680445540997}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1209.json
index d4b3cbe800a..13c7f906c17 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1209.json
@@ -1 +1 @@
-{"Abdominal hernia ": 5.164686893440604, "Abdominal mass ": 4.012595331183077, "Abnormal loss of weight ": 2.593827767860415, "Acoustic neuroma ": 11.877041876860147, "Acquired mixed hyperlipidaemia ": 489.9709026207715, "Actinic keratosis ": 25.115868048007226, "Acute left ventricular failure ": 7.199599984938528, "Acute respiratory failure ": 2.00413730896295, "Acute sinusitis ": 38.49239943697943, "Adjustment disorder ": 30.967569271475732, "Adverse event ": 2.3096075238192366, "Age-related macular degeneration ": 5.63826087602621, "Allergy to vaccine ": 13.050485509992846, "Anaemia of chronic disease ": 5.041247281409118, "Antibiotic therapy ": 31.48184819255657, "Anticoagulant therapy ": 37.13520669391215, "Anxiety ": 2.8970994780363406, "Anxiety disorder ": 4.29140252280999, "Aortic aneurysm ": 5.545350830174395, "Aortic arteriosclerosis ": 16.425604755919707, "Aortic dilatation ": 6.494769559683469, "Aortic disorder ": 10.55803426113151, "Aortic stenosis ": 3.136761200754285, "Aortic valve sclerosis ": 9.83081577944338, "Appendicectomy ": 6.517461369328814, "Arteriosclerosis ": 3.139044374566043, "Arteriosclerosis coronary artery ": 7.703860793763111, "Arthritis ": 4.156397842258508, "Arthropod bite ": 13.504660987059625, "Arthroscopy ": 11.369181996580211, "Astigmatism ": 19.59830769058446, "Atelectasis ": 2.3182320437588704, "Atrial flutter ": 2.0277423471486986, "Atrophic vulvovaginitis ": 33.04466134141133, "Autoimmune disorder ": 2.838036789335068, "Autonomic neuropathy ": 5.283435771539493, "Back disorder ": 2.864517250982201, "Barrett's oesophagus ": 5.6029332567183205, "Basal cell carcinoma ": 2.8018369152416187, "Bell's palsy ": 7.838862436325953, "Benign prostatic hyperplasia ": 17.210155236675153, "Bladder disorder ": 3.158742490371856, "Blepharitis ": 9.390606771240536, "Blindness ": 8.261004252476877, "Blindness unilateral ": 4.404971921774035, "Blood calcium abnormal ": 4.667163838601329, "Blood cholesterol abnormal ": 47.089015037076656, "Blood cholesterol increased ": 3.8458350865083823, "Blood disorder ": 3.5760586578067883, "Blood potassium abnormal ": 3.13892207570108, "Blood pressure abnormal ": 6.037714385944032, "Blood triglycerides abnormal ": 11.961908848001377, "Body mass index abnormal ": 238.97932108222813, "Body mass index increased ": 36.36773591746697, "Borderline glaucoma ": 34.32192604934259, "Bronchial hyperreactivity ": 3.1221362777724835, "Bronchitis ": 3.839916759821718, "Bronchitis chronic ": 6.110821475577046, "Cardiac disorder ": 2.4051129467115966, "Cardiac failure congestive ": 2.059926702823945, "Cardiac murmur ": 3.321291667150521, "Cardiac operation ": 2.415432798526544, "Cardiac pacemaker insertion ": 2.698815180337641, "Carotid arteriosclerosis ": 4.153971721405801, "Carotid artery disease ": 7.161937981930075, "Carotid artery occlusion ": 2.3278746787088505, "Carotid artery stenosis ": 8.229210202647831, "Carotid bruit ": 19.786381317737995, "Carpal tunnel decompression ": 8.206074668850489, "Carpal tunnel syndrome ": 8.274418285922948, "Cataract ": 7.046807611290622, "Cataract cortical ": 97.67816847681476, "Cataract nuclear ": 182.8715189798205, "Cataract operation ": 7.683389338662602, "Catheterisation cardiac ": 3.487179841369404, "Cellulitis ": 5.23092019367588, "Cerebral atrophy ": 3.4912753068742, "Cerebral small vessel ischaemic disease ": 67.47869830337089, "Cerebrovascular disorder ": 2.623814105010817, "Cerumen impaction ": 73.72581199397733, "Cervical radiculopathy ": 33.08728414826788, "Cervical spinal stenosis ": 15.012093805560996, "Chalazion ": 8.409123794092395, "Cholecystectomy ": 6.500390445283776, "Chronic inflammatory demyelinating polyradiculoneuropathy ": 7.049010180928649, "Chronic left ventricular failure ": 42.45776242319851, "Chronic obstructive pulmonary disease ": 5.565360111693838, "Chronic respiratory failure ": 6.331923596071674, "Claustrophobia ": 7.873274343145658, "Colonoscopy ": 35.99695135219424, "Colorectal adenoma ": 11.036312597761317, "Conjunctivitis allergic ": 3.931144467832018, "Conjunctivitis viral ": 21.88456741933103, "Contraindication to vaccination ": 21.664203187001128, "Corneal abrasion ": 12.484862253777656, "Corneal dystrophy ": 18.032862491740755, "Corneal opacity ": 6.069480620509656, "Corneal scar ": 44.56044824106241, "Coronary arterial stent insertion ": 3.675918806280832, "Coronary artery disease ": 3.702522649773601, "Costochondritis ": 2.325925479556899, "Cranial nerve disorder ": 5.87469429796592, "Cystocele ": 12.482295013046157, "Deafness ": 9.557754320972135, "Deafness bilateral ": 3.2207353680896342, "Deafness neurosensory ": 24.907899836589124, "Deafness unilateral ": 3.98832658817158, "Depression ": 3.627693464314411, "Dermal cyst ": 5.70329922960105, "Dermatitis ": 3.626117179895468, "Dermatitis atopic ": 2.609811975511752, "Dermatitis contact ": 7.734630316258774, "Dermatochalasis ": 55.37455434208067, "Diabetes mellitus ": 2.335580625021749, "Diabetic foot ": 2.1623559715197254, "Diabetic nephropathy ": 8.178549837230154, "Diabetic neuropathy ": 12.945531658703144, "Diabetic retinopathy ": 4.281667516142378, "Diabetic vascular disorder ": 30.444960257871987, "Diastolic dysfunction ": 4.652107857374554, "Disseminated varicella zoster vaccine virus infection ": 99.54034013877184, "Diuretic therapy ": 81.48589891249225, "Diverticulum ": 3.8329047830558176, "Diverticulum intestinal ": 3.1507552693242835, "Dry age-related macular degeneration ": 28.504464586709105, "Dry eye ": 6.100251831387898, "Dupuytren's contracture ": 4.910147733224104, "Dyslipidaemia ": 4.855031760757992, "Ear disorder ": 3.2103347400128683, "Ear pain ": 2.3051840614357166, "Emphysema ": 3.4545367110704635, "Encephalitis ": 2.811486779645027, "Encephalitis herpes ": 11.0755512626431, "Endoscopy ": 18.06499122502921, "Epicondylitis ": 4.426158506678191, "Epiretinal membrane ": 31.427946747425445, "Escherichia urinary tract infection ": 3.45164344427893, "Essential hypertension ": 71.06891966554274, "Eustachian tube dysfunction ": 22.709674856824957, "Exposure keratitis ": 127.74748647142104, "Extra dose administered ": 8.200312703226981, "Eye discharge ": 2.14234490059549, "Eye disorder ": 2.5532981991579757, "Eye infection ": 4.799395420799756, "Eye injury ": 2.8774390464823547, "Eye operation ": 2.331425337200373, "Eyelid ptosis ": 3.340530579989222, "Facial pain ": 3.5606281674251994, "Fibrocystic breast disease ": 10.297957616739248, "Fibromyalgia ": 2.2916462378410563, "Foot deformity ": 2.3036316008558164, "Foot operation ": 2.377305263020258, "Foreign body sensation in eyes ": 2.1563545715424257, "Frustration tolerance decreased ": 2.817179626055943, "Fungal skin infection ": 4.506964963583756, "Gallbladder operation ": 4.415855434840808, "Gastrooesophageal reflux disease ": 7.78073378978634, "Generalised anxiety disorder ": 18.170285042452846, "Genital herpes ": 4.811531776866793, "Genital herpes simplex ": 18.867533534476784, "Genital herpes zoster ": 39.46231972736071, "Giant cell arteritis ": 6.616122537711889, "Glaucoma ": 6.032526246744823, "Glucose tolerance impaired ": 17.75243995811166, "Goitre ": 4.380409437500573, "Gout ": 6.056440480471248, "Grief reaction ": 14.152414596794053, "Guillain-Barre syndrome ": 2.992409264921013, "Haemangioma of skin ": 9.083401029576477, "Haemorrhoids ": 2.2175998117468003, "Hepatic cyst ": 2.336137971959278, "Hernia ": 3.438175435487462, "Hernia repair ": 6.873119302981594, "Herpes dermatitis ": 14.271290395599584, "Herpes ophthalmic ": 13.007494699000096, "Herpes simplex ": 8.116162279543603, "Herpes virus infection ": 3.3273371846989366, "Herpes zoster ": 50.55248663934648, "Herpes zoster cutaneous disseminated ": 20.23082701366594, "Herpes zoster disseminated ": 83.19416761622605, "Herpes zoster infection neurological ": 41.1470387436672, "Herpes zoster meningoencephalitis ": 12.96453523217852, "Herpes zoster oticus ": 66.95677680885454, "Herpes zoster reactivation ": 59.07217233105953, "Hiatus hernia ": 3.074170269806032, "Hip arthroplasty ": 4.230668839777007, "Hordeolum ": 2.509776644258744, "Hypercholesterolaemia ": 5.684071235337333, "Hyperkeratosis ": 3.8778762548414303, "Hyperlipidaemia ": 29.05772636951609, "Hypermetropia ": 22.84129668947689, "Hyperparathyroidism ": 3.629773562872243, "Hypertension ": 2.1217684623846047, "Hypertensive heart disease ": 7.463199066449803, "Hypertensive nephropathy ": 32.10715896348368, "Hypertonic bladder ": 19.950667271697817, "Hypogonadism male ": 16.99356960924383, "Hypothyroidism ": 3.5631229431851064, "Hypovitaminosis ": 5.982363152033486, "Hysterectomy ": 9.396643114649471, "Ill-defined disorder ": 6.343437788983428, "Immune system disorder ": 29.045554190561877, "Impaired fasting glucose ": 87.26031977037316, "Impetigo ": 6.135473509847262, "Incorrect route of product administration ": 4.049389258655312, "Increased tendency to bruise ": 2.847784878443267, "Inguinal hernia ": 2.382894456960552, "Injection site cellulitis ": 9.622572306495094, "Injection site rash ": 2.763427012202728, "Injection site vesicles ": 4.253103075300228, "Intermittent claudication ": 5.160099673135114, "Intervertebral disc degeneration ": 10.702832518537573, "Intervertebral disc disorder ": 8.803671769929613, "Intervertebral disc protrusion ": 4.432769781081531, "Iridocyclitis ": 2.570573485855684, "Iritis ": 8.01080610508938, "Iron deficiency anaemia ": 3.61618860687412, "Ischaemic stroke ": 2.3377378250285927, "Joint injury ": 3.4829098160259115, "Keratitis ": 4.112810337089968, "Knee arthroplasty ": 8.676798999757185, "Knee operation ": 6.680789086079987, "Kyphosis ": 4.545257189281386, "Labelled drug-drug interaction issue ": 17.81219378337435, "Labyrinthitis ": 3.050958584191286, "Lacrimation decreased ": 13.157699378137997, "Large intestine benign neoplasm ": 41.413996076460165, "Large intestine polyp ": 8.159074353469759, "Left ventricular hypertrophy ": 5.63642101762027, "Lichen planus ": 3.0324280435932334, "Ligament sprain ": 5.649413402354802, "Limb injury ": 3.270131234152873, "Limb operation ": 2.22364390440566, "Lipoma ": 4.351657130454828, "Lower urinary tract symptoms ": 16.17324292387107, "Lumbar radiculopathy ": 59.21880598284709, "Lumbar spinal stenosis ": 21.522236952455497, "Lumbosacral radiculopathy ": 23.404036088623457, "Lyme disease ": 2.6831974103452803, "Lymphocyte percentage decreased ": 4.5548006185633945, "Macular degeneration ": 2.084731392308088, "Macular hole ": 5.734687094075265, "Major depression ": 8.639625671818244, "Mammogram abnormal ": 18.358284377925024, "Meibomian gland dysfunction ": 32.0153541750301, "Melanocytic naevus ": 10.73653273248661, "Meniere's disease ": 4.372665369048065, "Meniscus injury ": 4.731643656075844, "Menopausal symptoms ": 5.313546838501924, "Menopause ": 7.221315517760544, "Metabolic surgery ": 5.5518264464461, "Migraine without aura ": 6.890266185386682, "Mitral valve incompetence ": 2.440923727544879, "Mitral valve prolapse ": 3.701553899849742, "Muscle relaxant therapy ": 218.53919008947216, "Muscle strain ": 6.321185694276393, "Myelitis transverse ": 5.733914332188312, "Myelopathy ": 7.274613438673619, "Myofascial pain syndrome ": 8.38120436529354, "Myopia ": 4.930646479734463, "Nasal oedema ": 2.6097134084408986, "Nasal septum deviation ": 11.238121331867946, "Neck injury ": 2.794561064494443, "Neck surgery ": 7.642698585987916, "Necrotising retinitis ": 24.194802752771867, "Neoplasm skin ": 5.879093831947936, "Nephrolithiasis ": 2.32892741875493, "Nerve compression ": 2.610670728636749, "Nerve injury ": 11.338229505166307, "Nervous system disorder ": 2.7175111887767254, "Neuralgia ": 7.063246701746626, "Neuritis ": 5.400003832179604, "Neurodermatitis ": 3.1705791747851166, "Neurogenic bladder ": 3.1323021500467965, "Neuropathy peripheral ": 2.6458730394863523, "Neurotrophic keratopathy ": 106.38086844845338, "Nicotine dependence ": 2.352641027342492, "Nocturia ": 2.3678534303632417, "Normocytic anaemia ": 2.497668997278105, "Obesity ": 15.277143640395344, "Obstructive sleep apnoea syndrome ": 21.249320749623745, "Occipital neuralgia ": 8.34938428033506, "Occupational exposure to product ": 3.232285161238911, "Ocular hypertension ": 4.581015030890859, "Onychomycosis ": 6.148349457915384, "Open angle glaucoma ": 18.17196269105628, "Ophthalmic herpes simplex ": 47.09985954922732, "Ophthalmic herpes zoster ": 102.7002753113882, "Optic ischaemic neuropathy ": 2.229958495541152, "Optic nerve injury ": 5.5729332034412495, "Oral herpes ": 3.810454711025185, "Organic erectile dysfunction ": 19.441982514860808, "Osteoarthritis ": 8.998382647059312, "Osteopenia ": 2.185507406751505, "Otitis externa ": 12.10889728270801, "Otitis media ": 3.287192828625292, "Otitis media acute ": 7.778919171669348, "Overweight ": 14.152103584257732, "Paranasal sinus discomfort ": 2.9091104776320784, "Peptic ulcer ": 2.7326662008311007, "Peripheral arterial occlusive disease ": 3.865087411301512, "Peripheral vascular disorder ": 3.314793763181421, "Peripheral venous disease ": 3.5864718923126166, "Peroneal nerve palsy ": 2.9671968753821045, "Plantar fasciitis ": 3.979053448573323, "Polymyalgia rheumatica ": 6.885032098115992, "Polyneuropathy ": 2.063368375042501, "Poor quality sleep ": 2.739491859186051, "Post herpetic neuralgia ": 329.024380833753, "Post inflammatory pigmentation change ": 14.020808157928386, "Post-traumatic stress disorder ": 4.142306544511485, "Posterior capsule opacification ": 41.533977139766826, "Presbyopia ": 72.72294497439263, "Prostatic disorder ": 7.405651000272421, "Prostatitis ": 2.2365026655656544, "Prostatomegaly ": 5.84228560798611, "Pseudophakia ": 122.53392502395144, "Pulmonary mass ": 3.502448876018047, "Punctate keratitis ": 24.865210097230374, "Quality of life decreased ": 2.0274095443711047, "Radiculopathy ": 2.17258976451131, "Rash vesicular ": 29.70981862553993, "Rectocele ": 21.327620788775224, "Red cell distribution width increased ": 2.252389260982891, "Renal cyst ": 3.605832204091211, "Restless legs syndrome ": 4.2083433065172, "Retinal degeneration ": 11.905398788255424, "Retinal detachment ": 2.503996107269665, "Retinal disorder ": 2.977021239613837, "Retinal drusen ": 23.582424866923528, "Retinal tear ": 6.912282356473393, "Rhinitis allergic ": 13.313651559695588, "Rosacea ": 8.802447006537854, "Rotator cuff repair ": 5.462180156962764, "Rotator cuff syndrome ": 7.642729290842138, "Scab ": 3.5522107429754106, "Scar ": 17.04068537786901, "Sciatica ": 6.052735617914976, "Scoliosis ": 4.410059229193188, "Seasonal allergy ": 8.261526700599104, "Seborrhoeic dermatitis ": 14.317317930714903, "Seborrhoeic keratosis ": 60.672912563595176, "Secondary transmission ": 80.56599852933752, "Shoulder arthroplasty ": 7.058523283133602, "Shoulder operation ": 11.695241199809098, "Sialoadenitis ": 6.969878833291585, "Sinus congestion ": 2.2967643221686287, "Sinus disorder ": 3.938583846328531, "Skin abrasion ": 2.559447183834304, "Skin cancer ": 5.461614999824607, "Skin infection ": 2.3122884353416806, "Skin lesion ": 2.1200552263884025, "Skin papilloma ": 2.1999281008216918, "Sleep apnoea syndrome ": 5.143442676131692, "Sleep disorder ": 2.257511875863736, "Snoring ": 3.690172928231879, "Spinal disorder ": 3.530377752061156, "Spinal fusion surgery ": 8.847521952088963, "Spinal operation ": 7.114843973902861, "Spinal osteoarthritis ": 14.013917365510688, "Spinal stenosis ": 5.8646668845195125, "Spondylitis ": 2.6045687497375662, "Spondylolisthesis ": 7.257123795243408, "Stent placement ": 2.2969317012684654, "Stress ": 2.822684838816258, "Stress urinary incontinence ": 9.679072103604822, "Synovial cyst ": 6.313474926924271, "Temporomandibular pain and dysfunction syndrome ": 10.11146093499598, "Thyroid disorder ": 4.533358829503437, "Thyroid mass ": 6.5886007643980005, "Thyroidectomy ": 4.378751058950307, "Tinea pedis ": 4.6041639707257564, "Tobacco abuse ": 15.364687387318444, "Tonsillectomy ": 10.46303975015456, "Tricuspid valve incompetence ": 2.148413063730897, "Trigeminal neuralgia ": 6.66856368378855, "Trigger finger ": 10.66807378701282, "Type 2 diabetes mellitus ": 6.19144527342971, "Type IIa hyperlipidaemia ": 47.19605635139588, "Type V hyperlipidaemia ": 56.273148011420645, "Ulcerative keratitis ": 2.4644074591980454, "Umbilical hernia ": 4.25179769911184, "Upper respiratory tract infection ": 3.064717013662638, "Upper-airway cough syndrome ": 3.990006224925632, "Urge incontinence ": 11.866572033876968, "Urinary tract disorder ": 2.742348726621436, "VIth nerve paralysis ": 4.506964963583756, "Vaccination error ": 11.508274203990172, "Vaccination failure ": 9.14507482156081, "Vaccination site cellulitis ": 8.733367800009974, "Vaccination site rash ": 2.068398244515403, "Vaccination site vesicles ": 4.524481850795033, "Vaginal infection ": 2.0808275578654354, "Varicella ": 5.577965828526666, "Varicella virus test positive ": 57.61123800070495, "Varicella zoster pneumonia ": 73.02133441692403, "Varicella zoster virus infection ": 11.32545490064734, "Varicose vein ": 2.320067612114117, "Vertebral foraminal stenosis ": 12.821176609450546, "Vertigo positional ": 3.678494900597949, "Vestibular neuronitis ": 2.4643476771286768, "Vitamin B complex deficiency ": 11.323003200017338, "Vitamin B12 deficiency ": 10.579272743312004, "Vitamin D decreased ": 3.741944628578685, "Vitamin D deficiency ": 10.43365847233664, "Vitreous degeneration ": 68.902158181046, "Vitreous detachment ": 17.27819071894264, "Vitreous floaters ": 3.2667187511970104, "Weight abnormal ": 9.44750254504612, "Weight fluctuation ": 2.6375087600136995}
\ No newline at end of file
+{"Blood lactic acid increased": 53.96786311775678, "Hepatic steatosis": 22.559685416350383, "Hypoaesthesia": 2.252591092118696, "Lactic acidosis": 112.65864287560146, "Lipodystrophy acquired": 129.77964585708622, "Neuropathy peripheral": 22.936928760691483, "Pancreatitis": 22.351247477085668, "Pancreatitis acute": 21.72216881088159, "Polyneuropathy": 58.4463593594333, "Pregnancy": 75.94110485622062, "Weight decreased": 2.0873281334524787}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/121.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/121.json
index 17f2c6ee259..8e21acbb87c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/121.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/121.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 2.5492370835868856, "Affective disorder ": 5.059052774068652, "Alanine aminotransferase abnormal ": 30.99561154379193, "Amyotrophy ": 19.565235765802377, "Anaemia ": 2.005749835707711, "Anosmia ": 7.543077166591415, "Anti-cyclic citrullinated peptide antibody ": 23.573254037434868, "Anti-cyclic citrullinated peptide antibody positive ": 2.046979994793292, "Appetite disorder ": 6.181626236964057, "Apraxia ": 8.26798761133523, "Arthritis ": 2.370351010010433, "Aspirin-exacerbated respiratory disease ": 667.448664710335, "Asthma ": 14.703660184489836, "Asthma-chronic obstructive pulmonary disease overlap syndrome ": 78.89471318443336, "Asthmatic crisis ": 15.104651158862383, "Attention deficit hyperactivity disorder ": 2.84365553507557, "Autism spectrum disorder ": 3.592499070704044, "Blepharospasm ": 10.563219507758262, "Blood alkaline phosphatase abnormal ": 101.26146417182616, "Blood immunoglobulin E increased ": 20.24999798576366, "Blood insulin abnormal ": 94.8730509888974, "Body mass index increased ": 45.72553826290113, "Body temperature fluctuation ": 3.95702087283585, "Bronchiectasis ": 25.262507651313296, "Calcium deficiency ": 21.539035728952957, "Cardiac murmur ": 7.893784281673978, "Central obesity ": 15.770196113958123, "Choking ": 2.404065173054178, "Chondrocalcinosis ": 58.830644713481, "Chondrocalcinosis pyrophosphate ": 34.86290439608444, "Chronic obstructive pulmonary disease ": 10.079534371712144, "Chronic sinusitis ": 52.37197552871875, "Chronic spontaneous urticaria ": 19.082042532117885, "Colitis ": 13.987987656743774, "Colitis ulcerative ": 14.686878300851731, "Condition aggravated ": 2.5644233008085164, "Constipation ": 3.455575285974829, "Cough ": 2.6925439288912902, "Crystal arthropathy ": 382.83432380324575, "Cushing's syndrome ": 7.750653315880079, "Disease recurrence ": 2.1374249897447597, "Drug hypersensitivity ": 3.273125281812124, "Drug ineffective ": 2.6843357731491, "Dust allergy ": 33.820685612502025, "Dyspepsia ": 6.497273792486839, "Dyspnoea ": 2.751217065736715, "Dyspnoea exertional ": 14.882810343737576, "Dyspraxia ": 12.6253792159631, "Ear pruritus ": 14.316476362783142, "Eczema ": 16.34384639890735, "Eosinophil count abnormal ": 53.68464120784988, "Eosinophil count increased ": 6.95119126830032, "Eosinophilic bronchitis ": 69.19772567015505, "Epistaxis ": 5.292200363440197, "Erythema ": 2.3028426153764805, "Exercise tolerance decreased ": 2.652035219518057, "Eye pruritus ": 3.407650325512399, "Female genital tract fistula ": 85.7733474093521, "Forced expiratory volume abnormal ": 176.72227183573497, "Forced expiratory volume decreased ": 29.0509482766136, "Frequent bowel movements ": 28.91480097318433, "Frustration tolerance decreased ": 19.756671911972173, "Full blood count abnormal ": 47.969754872292114, "Gastroenteritis viral ": 5.184856361007884, "Gastrooesophageal reflux disease ": 8.66150726419908, "Generalised anxiety disorder ": 9.118546655741898, "Glaucoma ": 5.889531995987892, "Haematochezia ": 9.190147581552017, "Haemoptysis ": 2.089323539632589, "Hiatus hernia ": 6.146156286920398, "Hospitalisation ": 3.248076332303526, "Immune system disorder ": 3.0909841125903803, "Increased bronchial secretion ": 4.520626220632452, "Infusion related reaction ": 8.703427129513821, "Intellectual disability ": 4.295055557915918, "Intraocular pressure increased ": 6.406823546302142, "Lacrimation increased ": 2.397789322153405, "Loss of personal independence in daily activities ": 11.658809588355831, "Lung opacity ": 15.652962664824289, "Macular degeneration ": 100.631583862083, "Malignant mediastinal neoplasm ": 321.4682757996754, "Middle insomnia ": 3.040514724276893, "Motor developmental delay ": 16.659412148175193, "Movement disorder ": 2.196162140511912, "NSAID exacerbated respiratory disease ": 2578.1190087691425, "Nasal congestion ": 19.63620574961391, "Nasal crusting ": 27.4970156152809, "Nasal discomfort ": 13.284000866359689, "Nasal dryness ": 10.621506202579573, "Nasal obstruction ": 135.62439723234328, "Nasal oedema ": 13.542034530464951, "Nasal polyps ": 124.64345505077404, "Nasal septum perforation ": 33.312940071794905, "Nasal ulcer ": 23.839769141132308, "Obsessive-compulsive disorder ": 4.975782922883751, "Obstructive airways disorder ": 36.83179941451178, "Ocular discomfort ": 2.23193110671591, "Oral candidiasis ": 33.38011770190547, "Overweight ": 49.3208762989773, "Paraesthesia oral ": 13.36842235050235, "Paranasal sinus discomfort ": 18.23362315370565, "Parotitis ": 64.67500455446003, "Perioral dermatitis ": 16.534827696977914, "Pharyngeal inflammation ": 8.52371067975638, "Post-traumatic stress disorder ": 2.904813870503962, "Procedural pain ": 51.7033434624297, "Proctitis ": 75.78729699646041, "Product administration interrupted ": 10.035110074718933, "Product availability issue ": 2.9854771737362187, "Product complaint ": 6.145904474039615, "Product prescribing issue ": 10.770024469938852, "Productive cough ": 7.774087740959746, "Psychomotor hyperactivity ": 2.1886475041574243, "Pulmonary function test abnormal ": 21.718539437471865, "Pulmonary mass ": 7.133560864907831, "Radiculopathy ": 63.90543227694531, "Rectal haemorrhage ": 10.586676711272448, "Respiratory gas exchange disorder ": 65.02341719943165, "Respiratory symptom ": 4.037465408132624, "Respiratory tract infection ": 16.89078865799146, "Respiratory tract inflammation ": 27.946816646585976, "Restrictive pulmonary disease ": 20.30760107716089, "Reversible airways obstruction ": 94.17905426529416, "Rhinalgia ": 25.91224553379479, "Rhinitis ": 4.128318354387429, "Rhinitis allergic ": 20.09440589859913, "Rhinorrhoea ": 11.883770938545128, "Sarcoidosis ": 8.412933791849955, "Seasonal allergy ": 9.67220499431581, "Secretion discharge ": 63.076199352665874, "Sensory processing disorder ": 57.05568389839017, "Sinus congestion ": 9.961862135316215, "Sinus headache ": 2.794226439797592, "Sinusitis ": 9.980935133095418, "Sleep apnoea syndrome ": 17.295993368830857, "Sleep disorder due to a general medical condition ": 46.24329138886964, "Sneezing ": 6.813494220316039, "Social avoidant behaviour ": 3.2169048698569287, "Sputum discoloured ": 30.49434085564466, "Stent placement ": 11.597411926819522, "Stereotypy ": 12.715941350773315, "Taste disorder ": 2.9794160195307478, "Therapeutic product effect incomplete ": 28.0658591091407, "Therapy interrupted ": 2.307831217583779, "Throat clearing ": 205.87447492713576, "Throat irritation ": 3.264730080379355, "Thyroid cancer ": 2.527365830530212, "Thyroid disorder ": 4.258936277735723, "Thyroid neoplasm ": 13.731338799572873, "Thyroidectomy ": 12.103747226502794, "Tooth development disorder ": 70.71829513793976, "Total lung capacity decreased ": 12.10264314939236, "Total lung capacity increased ": 223.62474719659772, "Tracheomalacia ": 46.57433352542154, "Upper respiratory tract infection ": 3.0503914026203462, "Upper-airway cough syndrome ": 9.224396721177278, "Vaginal discharge ": 45.67737894435127, "Vaginal flatulence ": 103.09892772177292, "Vital capacity decreased ": 33.708023149884795, "Weight decreased ": 2.7536061956871776, "Wheezing ": 16.320894925417466}
\ No newline at end of file
+{"Acquired immunodeficiency syndrome": 4.597678262491591, "Acute kidney injury": 4.097155951919213, "Agoraphobia": 2.505821738646417, "Albuminuria": 4.004876510141483, "Alveolar bone resorption": 17.917211846154192, "Anaemia of chronic disease": 2.719284791053432, "Anhedonia": 62.04638342318317, "Ankle fracture": 20.673204044029315, "Anxiety": 9.981624764370116, "Avulsion fracture": 24.29557802455055, "Blood creatine increased": 4.103640089140098, "Blood creatinine abnormal": 4.259964904495027, "Blood creatinine increased": 8.230030617289433, "Bone deformity": 4.209826967561131, "Bone demineralisation": 74.28981304094967, "Bone density abnormal": 57.33200922846272, "Bone density decreased": 78.92080364047796, "Bone disorder": 28.905640623069985, "Bone fragmentation": 14.614078007966857, "Bone infarction": 9.52679237465253, "Bone loss": 64.02976358464679, "Bone metabolism disorder": 6.875806724582245, "CD4 lymphocytes abnormal": 14.302981984996524, "CD4 lymphocytes decreased": 2.9977831276002926, "Calcium deficiency": 3.749111078947583, "Cervical radiculopathy": 3.4669962240959498, "Cervical spinal stenosis": 6.869731972045208, "Cervical vertebral fracture": 5.562755034391413, "Chronic kidney disease": 54.29792737001157, "Chronic kidney disease-mineral and bone disorder": 48.94047084490235, "Clavicle fracture": 16.94770191990752, "Compression fracture": 4.588184112167369, "Congenital cystic kidney disease": 4.272644299873296, "Craniofacial fracture": 10.843627342245624, "Decreased activity": 10.947133483936566, "Degenerative bone disease": 42.43547536308009, "Dental caries": 17.306427976082787, "Dental pulp disorder": 41.02085900601698, "Dysstasia": 3.24382861911607, "Economic problem": 51.50536875963143, "Emotional distress": 45.881260610515625, "Enamel anomaly": 4.178173781972772, "End stage renal disease": 34.00940475203284, "Enzyme level increased": 2.619649144025735, "Fanconi syndrome": 2.36853567198644, "Fanconi syndrome acquired": 19.700772038592092, "Fat redistribution": 4.269324761278628, "Fear-related avoidance of activities": 29.395048642908076, "Femoral neck fracture": 3.934645453623324, "Femur fracture": 4.9124971686279215, "Fibula fracture": 27.272547950066087, "Foot fracture": 26.79023749201191, "Forearm fracture": 15.18377083368827, "Fracture": 25.288779362352965, "Fracture pain": 4.322859759935198, "Fractured coccyx": 10.80446523489447, "Fractured sacrum": 9.074203406325076, "Genotype drug resistance test positive": 2.8460607298242477, "Glomerular filtration rate abnormal": 29.376101713647127, "Glomerular filtration rate decreased": 4.832647256171353, "Glomerular filtration rate increased": 9.138976620101262, "Glycosuria": 4.516914326705232, "Hand fracture": 37.55777014417928, "Hip arthroplasty": 10.137160501496668, "Hip fracture": 7.150603043788784, "Hip surgery": 2.415638287910548, "Humerus fracture": 10.636130754983602, "Hydronephrosis": 2.0739018669978253, "Hyperparathyroidism": 3.728871101262186, "Hyperparathyroidism secondary": 12.725928471375267, "Hypertensive nephropathy": 5.815055212860129, "Immune reconstitution inflammatory syndrome": 2.084981101782758, "Intervertebral disc degeneration": 16.00125659303533, "Intervertebral disc protrusion": 2.1685607716856103, "Intervertebral disc space narrowing": 2.879094128470016, "Jaw fracture": 16.896515538322188, "Kidney small": 7.327401107792125, "Limb fracture": 30.609643191425494, "Loose tooth": 2.1689818942965498, "Loss of personal independence in daily activities": 2.398091434901302, "Lower limb fracture": 8.790829364997713, "Lumbar spinal stenosis": 3.825373136208016, "Lumbar vertebral fracture": 4.7439487263185, "Medical diet": 14.768980779681495, "Multiple fractures": 63.594116006248285, "Nephrectomy": 3.198416145675873, "Nephrogenic anaemia": 13.7850316781125, "Nephrolithiasis": 3.398205015927867, "Nephropathy": 41.38825144499997, "Osteoarthritis": 7.662553839518045, "Osteochondrosis": 2.570138085112598, "Osteogenesis imperfecta": 2.58545097622199, "Osteomalacia": 34.36806163286362, "Osteonecrosis": 53.32455384026002, "Osteopenia": 68.30928615663177, "Osteoporosis": 48.29826511971717, "Osteoporotic fracture": 25.654476190124672, "Pain": 4.19829175300006, "Partner stress": 2.734718924897819, "Patella fracture": 10.587592173647264, "Patellofemoral pain syndrome": 3.122113395383359, "Pathological fracture": 6.539249611821661, "Pelvic fracture": 2.069185070171703, "Periodontal disease": 3.0587385859631846, "Pituitary-dependent Cushing's syndrome": 2.7535101659207224, "Poor dental condition": 9.919932317887788, "Posterior tibial tendon dysfunction": 56.9452965698249, "Pregnancy with implant contraceptive": 5.340899951659084, "Protein total abnormal": 43.59832683357723, "Protein total increased": 18.384247537775146, "Protein urine present": 5.3952579325425045, "Proteinuria": 5.921561926870156, "Pulpless tooth": 6.945347866172387, "Quality of life decreased": 13.159943557925674, "Radius fracture": 21.679125616598764, "Renal atrophy": 7.678270354128946, "Renal cyst": 8.599237624480564, "Renal failure": 20.318257423684663, "Renal impairment": 6.5226978716165815, "Renal injury": 99.81186483714768, "Renal mass": 5.437123618537491, "Renal transplant": 4.142540604227387, "Renal tubular acidosis": 4.802352385306294, "Renal tubular disorder": 2.6997633626583184, "Renal tubular dysfunction": 6.675297066340862, "Renal tubular injury": 13.385585876153572, "Renal tubular necrosis": 3.3588408399980456, "Rib fracture": 14.367078261012106, "Scapula fracture": 23.309426260050543, "Shoulder arthroplasty": 5.2632644813176, "Shoulder fracture": 10.353014491078952, "Sitting disability": 6.293500869826232, "Skeletal injury": 114.84829914618383, "Skull fracture": 2.4086552687920872, "Spinal column injury": 5.471946964134474, "Spinal compression fracture": 7.208791220765313, "Spinal deformity": 2.9910831397415096, "Spinal fracture": 5.709238225830615, "Spinal fusion surgery": 2.307542517430605, "Spinal osteoarthritis": 10.124804598898814, "Spinal stenosis": 5.517630447506515, "Spondylitic myelopathy": 31.002743108773984, "Spondylolisthesis": 12.80455306485301, "Spondylolysis": 13.64105297037372, "Stress fracture": 12.024172685464016, "T-lymphocyte count decreased": 5.657557063963902, "Teeth brittle": 36.19941505095316, "Thoracic vertebral fracture": 6.744196250722952, "Tibia fracture": 21.432927446876384, "Tooth disorder": 2.7618043109523787, "Tooth erosion": 2.060872844639641, "Tooth extraction": 8.557299879449575, "Tooth fracture": 35.97445322838687, "Tooth impacted": 10.067111282495947, "Tooth injury": 843.057173709686, "Tooth loss": 86.98135302347433, "Traumatic fracture": 2.331468200956493, "Ulna fracture": 18.301447720043832, "Underweight": 8.116141810017218, "Unemployment": 12.338587884096142, "Upper limb fracture": 8.624806548126564, "Vertebral foraminal stenosis": 14.77106299685714, "Vertebral osteophyte": 4.343305333793597, "Viral load increased": 2.9370126841808157, "Virologic failure": 2.063980447975663, "Vitamin D decreased": 2.8760969327266577, "Vitamin D deficiency": 52.40797324636521, "Wrist fracture": 25.625025232738203}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1210.json
index a4fd6b3ad20..242e4a872f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1210.json
@@ -1 +1 @@
-{"Application site erythema ": 30.13932401420249, "Application site pain ": 12.679312445768767, "Application site reaction ": 39.556561252101694, "Application site scab ": 461.3967579998862, "Blister ": 3.5442575108053176, "Decreased appetite ": 2.670832543963208, "Erythema ": 4.986901281586055, "Erythema multiforme ": 9.560866635513914, "Inflammation ": 4.791144196106012, "Influenza like illness ": 4.690176277945901, "Oropharyngeal pain ": 2.079486191570606, "Scab ": 135.80833631003176, "Skin burning sensation ": 9.35178344231789, "Skin reaction ": 19.03068767252705, "Wound ": 7.660046100007945}
\ No newline at end of file
+{"Anaemia": 2.777638455063156, "Hypoaesthesia": 3.727758363392819, "Leukopenia": 16.920384319985292, "Myelodysplastic syndrome": 139.32337300908432, "Myelosuppression": 8.677926270546802, "Neutropenia": 31.66644427692723, "Neutrophil count decreased": 13.626062095132308, "Off label use": 2.2928321440164927, "Platelet count decreased": 33.75838731454105, "Thrombocytopenia": 23.737298653791303, "White blood cell count decreased": 22.088116770801957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1211.json
index 2c05f95aa0d..e95c8a5f8f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1211.json
@@ -1 +1 @@
-{"Diarrhoea ": 4.664401319104965}
\ No newline at end of file
+{"Abdominal pain": 4.138599471559138, "Alanine aminotransferase increased": 5.377769299481594, "Amylase increased": 18.37404941793895, "Aspartate aminotransferase increased": 6.535088991362754, "Blood bilirubin increased": 2.7379674010269577, "Blood creatine phosphokinase increased": 5.953186378966396, "Blood creatinine increased": 2.7379568590437056, "Blood lactate dehydrogenase increased": 5.124833864366321, "Conjunctivitis": 9.77045401966187, "Cough": 2.8727930728768216, "Drug hypersensitivity": 3.369211735638504, "Haematocrit decreased": 5.334144563589491, "Hypersensitivity": 11.9867810876284, "Hypotension": 2.956426684467104, "Hypoxia": 5.229033669015095, "Ill-defined disorder": 4.426544322570443, "Lipase increased": 11.904355371471253, "Liver function test abnormal": 4.63103788702584, "Lung infiltration": 9.54455091703132, "Malaise": 2.234328024803486, "Oedema": 3.284761378562467, "Pancreatitis": 2.743751463134501, "Pneumocystis jirovecii pneumonia": 10.561805036617551, "Pyrexia": 2.4477482129329, "Rash": 3.0900972354029066, "Rash macular": 4.197702960892846, "Rash maculo-papular": 9.857993925837802, "Red blood cell count decreased": 5.033734481746527, "Tachycardia": 2.93189575200048, "Vomiting": 2.6955103850639395}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1212.json
index 009960b5f4f..1ace3e15131 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1212.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.536820778793655, "Abdominal pain upper ": 8.253573309960352, "Angina pectoris ": 15.01791663778948, "Angioedema ": 4.551821124708186, "Coronary artery thrombosis ": 160.65552500694767, "Drug ineffective ": 3.1038392149901366, "Drug interaction ": 2.22771476481896, "Dyspepsia ": 8.012185363188555, "Epistaxis ": 15.19584620684367, "Erythema ": 4.047587861710797, "Product substitution issue ": 27.06103239303645, "Pruritus ": 7.78500757438934, "Rash ": 2.74612598197987, "Urticaria ": 9.606667415344369, "Vascular stent thrombosis ": 138.0150982923855}
\ No newline at end of file
+{"Anaemia": 45.80609921184413, "Weight decreased": 3.842837775259624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1213.json
index 728327cb18e..086ad15095a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1213.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 4.974195543518177, "Abscess limb ": 8.907174373435073, "Aggression ": 7.693713985210725, "Agitation ": 16.09520139701912, "Akathisia ": 29.23638263451846, "Altered state of consciousness ": 6.098538538996962, "Amnesia ": 2.9605379745798617, "Antipsychotic drug level increased ": 11.793153247741134, "Anxiety ": 2.55641610942508, "Ataxia ": 22.57490787699817, "Balance disorder ": 5.496747060021855, "Blood pressure decreased ": 3.847174014593083, "Blood pressure increased ": 3.8597944659133, "Bradyphrenia ": 5.382589566057559, "Cognitive disorder ": 3.628932009166916, "Coma ": 5.448804033078474, "Confusional state ": 14.5999685816965, "Consciousness fluctuating ": 23.833402679072265, "Coordination abnormal ": 5.333590560366172, "Delirium ": 15.587739702654378, "Delusion ": 3.6048305583936657, "Depressed level of consciousness ": 6.974873881044728, "Disorientation ": 29.82390288543815, "Disturbance in attention ": 3.193905399840759, "Dizziness ": 2.9243051032934058, "Drug level decreased ": 4.112976623075581, "Drug level increased ": 4.2712946673072505, "Dysarthria ": 58.70617919143494, "Dyskinesia ": 7.768752914180816, "Dysstasia ": 4.683869315360095, "Dystonia ": 4.480892946158898, "Extrapyramidal disorder ": 24.678070147681662, "Feeling drunk ": 23.81473364229841, "Gait disturbance ": 4.805018332407942, "Hallucination, auditory ": 3.010679029354051, "Hallucination, visual ": 2.544636836470833, "Heart rate increased ": 5.069417699783813, "Hypersomnia ": 6.416259329163188, "Hypertension ": 2.539246086510817, "Hypotension ": 2.4756405231120846, "Hypotonia ": 3.0019890175146755, "Immediate post-injection reaction ": 113.16399785885174, "Incoherent ": 14.516592500646311, "Incorrect route of product administration ": 2.897577996630229, "Injection related reaction ": 30.009545814606085, "Injection site abscess ": 105.09789913813586, "Injection site extravasation ": 9.81296537995781, "Injection site haemorrhage ": 8.814872713036596, "Injection site mass ": 3.757335327248045, "Loss of consciousness ": 2.677706478363381, "Miosis ": 7.962094257083629, "Muscle rigidity ": 5.275722377631711, "Muscle twitching ": 2.5134405385365186, "Neuroleptic malignant syndrome ": 4.160085951465657, "Overdose ": 2.8951672394409647, "Pallor ": 4.008174543568239, "Post procedural complication ": 88.53570773576514, "Post-injection delirium sedation syndrome ": 3968.163149506781, "Prescribed overdose ": 25.019653221165527, "Product administered at inappropriate site ": 7.380180241670926, "Psychomotor hyperactivity ": 18.42425375766652, "Psychotic disorder ": 6.155587087679568, "Restless legs syndrome ": 5.691738086625223, "Restlessness ": 13.442609828665727, "Salivary hypersecretion ": 4.118029418083848, "Schizophrenia ": 21.36373084332392, "Sedation ": 106.64327216150753, "Sedation complication ": 16.4995846831076, "Sinus tachycardia ": 4.280952019551647, "Somnolence ": 13.286736649537692, "Sopor ": 9.28064573873982, "Speech disorder ": 11.555275411917076, "Stupor ": 10.97224510541739, "Tachycardia ": 4.088564252873231, "Tardive dyskinesia ": 5.6349484121202185, "Unresponsive to stimuli ": 7.946171076445163, "Urinary incontinence ": 2.6666043959039936, "Vertigo ": 2.57662937836009, "Weight increased ": 3.4178019852734374}
\ No newline at end of file
+{"Drug ineffective": 5.025865078162145, "Neutropenia": 14.511392838905897}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1214.json
index 4aa77360115..d6f542efb0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1214.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 3.566399861795604, "Abnormal weight gain ": 8.664802590360368, "Abulia ": 6.440529739071105, "Accidental overdose ": 2.174367119340546, "Acidosis ": 2.216967025830745, "Acute psychosis ": 5.174574349681914, "Affect lability ": 2.343477978976052, "Aggression ": 4.120879718859056, "Agitation ": 4.668850229763304, "Agitation neonatal ": 8.28936972127874, "Akathisia ": 17.46367824396271, "Akinesia ": 2.704758957505391, "Alanine aminotransferase increased ": 4.010272484062591, "Alcohol abuse ": 2.897917832979334, "Alcohol poisoning ": 4.09410588870549, "Alcohol withdrawal syndrome ": 8.77376466562783, "Alcoholism ": 6.73902509706444, "Altered state of consciousness ": 3.4411979518512434, "Amylase increased ": 2.560621699453914, "Anger ": 2.424903205000438, "Angle closure glaucoma ": 2.476663455096601, "Anticholinergic syndrome ": 4.0707804444432965, "Antidepressant drug level increased ": 16.890541440676117, "Antipsychotic drug level increased ": 4.8880740623079, "Apallic syndrome ": 11.130878533341958, "Apathy ": 3.716186082816292, "Apgar score low ": 3.910623778748796, "Appetite disorder ": 2.127353234777491, "Aspartate aminotransferase increased ": 4.308038550707559, "Aspiration ": 3.030996202754517, "Ataxia ": 2.008740988940944, "Atrioventricular block second degree ": 2.965062409514157, "Autonomic nervous system imbalance ": 2.2989511702555423, "Behaviour disorder ": 2.513334593176341, "Binge eating ": 5.963426213338195, "Bipolar I disorder ": 8.433214361337289, "Bipolar disorder ": 7.550605157566669, "Bladder dilatation ": 4.166996749933885, "Blood alkaline phosphatase increased ": 3.062838422163804, "Blood chloride decreased ": 2.3126415676723826, "Blood cholesterol abnormal ": 18.721964369663095, "Blood cholesterol increased ": 7.148705009319468, "Blood creatine phosphokinase MB increased ": 2.370075140237085, "Blood creatine phosphokinase increased ": 9.383103472940888, "Blood glucose increased ": 2.584120456938054, "Blood lactate dehydrogenase increased ": 2.387142234485301, "Blood prolactin increased ": 21.685241915982584, "Blood sodium decreased ": 2.450780305457465, "Blood triglycerides increased ": 33.84626014211938, "Body mass index increased ": 3.419602997968908, "Bradykinesia ": 2.7018454460739987, "Bradyphrenia ": 2.6534028205758537, "Brain death ": 2.70301258780795, "Brain injury ": 2.427785694793206, "Breast enlargement ": 3.420498989317903, "Bruxism ": 2.483291708957956, "Bundle branch block right ": 2.09361369094556, "Cardiac hypertrophy ": 3.188004540090515, "Catatonia ": 14.01385406055225, "Cerebral atrophy ": 2.798446420336941, "Cerebrovascular disorder ": 3.912715065415471, "Cholelithiasis ": 2.2814739803491992, "Choreoathetosis ": 4.767504971440186, "Clonic convulsion ": 3.15310569170505, "Clonus ": 2.074164085782093, "Cogwheel rigidity ": 17.53869953576088, "Coma ": 5.732816550082031, "Communication disorder ": 2.3856103067994647, "Completed suicide ": 2.7594506840860022, "Craniocerebral injury ": 2.2033645574720486, "Decreased interest ": 2.7069383970640644, "Decubitus ulcer ": 3.724063753471079, "Delirium ": 5.092557345386584, "Delusion ": 8.217355103437207, "Depressed level of consciousness ": 2.901233265934018, "Depressive symptom ": 2.4368056075384312, "Diabetes insipidus ": 3.4326556602616947, "Diabetes mellitus ": 27.945370773614137, "Diabetes mellitus inadequate control ": 2.2571293419371847, "Diabetic coma ": 49.46844437744479, "Diabetic complication ": 3.612306794849199, "Diabetic foot ": 2.969149638576205, "Diabetic hyperglycaemic coma ": 6.794034007900975, "Diabetic hyperosmolar coma ": 75.06022336659977, "Diabetic ketoacidosis ": 9.708810155299544, "Diabetic ketosis ": 15.38794202383344, "Diabetic nephropathy ": 10.300323979748224, "Diabetic neuropathy ": 19.57954386470773, "Diabetic retinopathy ": 3.491502538606862, "Diet refusal ": 5.387113282423931, "Disinhibition ": 2.931223054429402, "Disorientation ": 2.227140069878215, "Drooling ": 10.59189724131937, "Drug interaction ": 2.130968536104548, "Drug level increased ": 2.7521604163721265, "Drug use disorder ": 2.339296383948818, "Drug withdrawal syndrome neonatal ": 2.6115860446176558, "Dysarthria ": 2.852999275591684, "Dyskinesia ": 6.596708984899679, "Dyslalia ": 2.4759309683808337, "Dyslipidaemia ": 16.1814252035681, "Dysphemia ": 3.370030340456351, "Dystonia ": 13.317688292937348, "Electrocardiogram QT prolonged ": 4.594499426067631, "Electrocardiogram abnormal ": 2.3059323158623317, "Electroencephalogram abnormal ": 5.525788423732841, "Emotional disorder ": 2.3817556488502776, "Emotional poverty ": 7.611317837003887, "Endotracheal intubation ": 3.821457620439124, "Enuresis ": 3.4983951516448752, "Erectile dysfunction ": 3.8361869473422616, "Essential hypertension ": 2.396428503018617, "Extrapyramidal disorder ": 17.223853266768288, "Eye movement disorder ": 2.5836841658192555, "Faecaloma ": 2.451650984361995, "Fear ": 2.039911755356885, "Flat affect ": 8.35110303422757, "Food craving ": 7.179228382130544, "Galactorrhoea ": 18.076007985334044, "Gamma-glutamyltransferase increased ": 4.241921089613284, "Gastrointestinal oedema ": 3.0268398602898263, "Gaze palsy ": 2.1670657168287693, "Generalised anxiety disorder ": 3.138172305162715, "Generalised tonic-clonic seizure ": 5.9862343331461885, "Gestational diabetes ": 10.068843221680137, "Glucose tolerance impaired ": 15.224548656496314, "Glucose urine present ": 4.557271525088346, "Glutamate dehydrogenase increased ": 22.79795703353525, "Glycosuria ": 11.715524148597604, "Granulocytopenia ": 2.1178301208937627, "Gynaecomastia ": 9.252248870444353, "Hallucination ": 2.159350643355357, "Hallucination, auditory ": 6.832288572019277, "Hallucinations, mixed ": 2.657407961420685, "Hepatic enzyme abnormal ": 2.7636323268437946, "Hepatic enzyme increased ": 2.8548741222927885, "Hepatic steatosis ": 9.316903275164472, "High density lipoprotein decreased ": 6.47134708074725, "Homicidal ideation ": 3.069224600526086, "Hospitalisation ": 2.049682089854247, "Hostility ": 5.845001153648316, "Hunger ": 3.0862484602135645, "Hypercapnia ": 4.593318771609615, "Hypercholesterolaemia ": 8.911636697864235, "Hyperglycaemia ": 8.739558623725001, "Hyperglycaemic hyperosmolar nonketotic syndrome ": 17.029439724273008, "Hyperkinesia ": 4.524166563001368, "Hyperlipidaemia ": 16.807143223473794, "Hypernatraemia ": 3.954822764883928, "Hyperosmolar state ": 25.421020597272967, "Hyperphagia ": 23.176904236376306, "Hyperprolactinaemia ": 14.304159997413674, "Hypersomnia ": 3.0484420696777907, "Hyperthermia ": 3.820736865382058, "Hyperthermia malignant ": 3.5785457210063467, "Hypertonia ": 3.079811398520228, "Hypertriglyceridaemia ": 10.606737216144456, "Hypogonadism ": 3.4909112197528485, "Hypomania ": 4.824270892076987, "Hyponatraemia ": 2.8557417266785845, "Hypothermia ": 4.182162221453252, "Hypotonia neonatal ": 8.021537254859577, "Hypoventilation ": 2.681014305037764, "Hypoxic-ischaemic encephalopathy ": 3.288391837224776, "Ileus ": 2.752931906856737, "Ileus paralytic ": 4.308669342203076, "Illusion ": 2.438440532483894, "Impaired fasting glucose ": 9.472145022956637, "Inappropriate affect ": 3.658862029781966, "Inappropriate antidiuretic hormone secretion ": 4.491925364503508, "Incoherent ": 2.902030991375747, "Incontinence ": 4.261679012117064, "Increased appetite ": 18.71879465352872, "Infantile apnoea ": 3.038217069702191, "Insulin resistance ": 3.889250128705401, "Insulin-requiring type 2 diabetes mellitus ": 19.914807531028707, "Intentional overdose ": 7.941652174465774, "Intentional self-injury ": 3.0418204352096465, "Intestinal dilatation ": 4.208933860377842, "Iron deficiency anaemia ": 2.342445791629729, "Ketoacidosis ": 5.664235703338711, "Ketonuria ": 6.1369292381943765, "Ketosis ": 3.2793548960857444, "Left ventricular hypertrophy ": 5.813500893793271, "Leukocytosis ": 2.9899729898801004, "Leukopenia ": 2.025476611164348, "Libido decreased ": 2.4291218071755067, "Libido disorder ": 5.011274901838199, "Lipase increased ": 2.1135296053248007, "Lipids abnormal ": 8.691064027313393, "Lipids increased ": 12.961412966144104, "Logorrhoea ": 3.7534733630240473, "Long QT syndrome ": 2.101405788258744, "Low density lipoprotein increased ": 5.355905437674048, "Major depression ": 3.316289176196924, "Mania ": 9.842347318232331, "Mental disorder ": 3.655220285092621, "Mental impairment ": 2.1677128202902334, "Mental status changes ": 2.4106202658282565, "Metabolic disorder ": 10.252153690012651, "Metabolic syndrome ": 45.67785530482576, "Microalbuminuria ": 7.341479726927162, "Micturition disorder ": 2.2019781419053555, "Miosis ": 6.142805859887483, "Mixed liver injury ": 2.1296587495833457, "Muscle rigidity ": 11.520855826122212, "Mutism ": 7.974915111242755, "Myoclonus ": 2.511097029462208, "Myoglobin blood increased ": 4.32845365190316, "Neonatal respiratory distress ": 2.714470591450501, "Neonatal respiratory distress syndrome ": 4.484552222197485, "Nephrogenic diabetes insipidus ": 3.201542183250081, "Neuroleptic malignant syndrome ": 43.50682076135289, "Neutrophil count increased ": 2.435738739663856, "Nuchal rigidity ": 2.0007899326893392, "Obesity ": 15.727893569764973, "Obsessive thoughts ": 9.106373952905454, "Obsessive-compulsive disorder ": 4.350587210559445, "Obstructive sleep apnoea syndrome ": 3.2927071125975385, "Oculogyric crisis ": 8.815602300199465, "Oedema peripheral ": 2.180975493732439, "Onychomycosis ": 3.487010150680951, "Opisthotonus ": 4.568121020654727, "Orthostatic hypotension ": 2.26877459989974, "Overdose ": 4.436000958492175, "Overweight ": 4.157780558618842, "Pancreatic disorder ": 2.9054042186608093, "Pancreatic pseudocyst ": 4.596008826205094, "Pancreatitis ": 5.188768890673827, "Pancreatitis acute ": 2.774000244627797, "Pancreatitis chronic ": 4.508069701474809, "Pancreatitis necrotising ": 2.225011387348092, "Pancreatitis relapsing ": 4.3143328506515095, "Paranoia ": 4.850032534517471, "Parkinson's disease ": 2.54374095667948, "Parkinsonian gait ": 7.115324045415322, "Parkinsonism ": 15.681670210029065, "Peripheral venous disease ": 2.631285683951333, "Persecutory delusion ": 8.148108422900913, "Personality disorder ": 3.182268678831566, "Physical assault ": 3.459840721567651, "Pituitary tumour benign ": 3.432428826828059, "Pleurothotonus ": 13.29450809415053, "Pneumonia aspiration ": 5.425633561563041, "Polydipsia ": 25.09898153193511, "Polyuria ": 6.273739608579961, "Poor feeding infant ": 2.818547464676096, "Poor peripheral circulation ": 2.746893796203969, "Postresuscitation encephalopathy ": 58.74823363078491, "Posture abnormal ": 3.7193035578131823, "Potentiating drug interaction ": 3.118373461953376, "Prescribed overdose ": 43.68725474392463, "Priapism ": 12.411333828450598, "Prothrombin time shortened ": 2.8762673410982744, "Protrusion tongue ": 7.695042052797245, "Psychiatric decompensation ": 8.906618439569613, "Psychiatric symptom ": 6.873586095912122, "Psychomotor hyperactivity ": 3.7529999391417967, "Psychomotor retardation ": 5.2300472652238135, "Psychotic disorder ": 8.378843721672734, "Pulmonary embolism ": 2.1530327472684765, "Pulmonary infarction ": 2.2766425526113023, "Reduced facial expression ": 6.65388253231199, "Respiratory depression ": 3.803655832250898, "Respiratory disorder neonatal ": 4.234480986408012, "Respiratory rate decreased ": 2.668268690365525, "Restless legs syndrome ": 2.030360964883424, "Restlessness ": 3.2539282386160946, "Rhabdomyolysis ": 6.191222633861633, "Salivary hypersecretion ": 4.97840556391158, "Schizoaffective disorder ": 8.878148154916273, "Schizophrenia ": 17.08547428508869, "Schizophreniform disorder ": 10.424357905123252, "Sedation ": 7.796374294609893, "Sedation complication ": 4.940327508195969, "Seizure ": 2.3219443366647696, "Selective eating disorder ": 3.9440043436217342, "Self esteem decreased ": 7.115552077342087, "Self-destructive behaviour ": 4.659190558155582, "Self-injurious ideation ": 4.0223846981473885, "Serotonin syndrome ": 3.1322252258774474, "Sexual dysfunction ": 3.001530121166997, "Sinus tachycardia ": 3.3499115780926965, "Skin striae ": 4.268365028069802, "Sleep apnoea syndrome ": 3.5518991829703337, "Slow response to stimuli ": 4.107898254638778, "Sluggishness ": 2.448737819521622, "Social avoidant behaviour ": 4.470849860454311, "Soliloquy ": 7.375252268434184, "Somnambulism ": 2.535021429605959, "Somnolence ": 2.9963627612934185, "Somnolence neonatal ": 13.438557631669282, "Sopor ": 5.251701376504839, "Speech disorder ": 2.3416074504669715, "Staring ": 2.5069869789393464, "Stupor ": 4.414903719105964, "Sudden cardiac death ": 2.0408116117964887, "Sudden death ": 7.7719381651965245, "Suicidal behaviour ": 3.0942742959344445, "Suicidal ideation ": 3.47952479444643, "Suicide attempt ": 8.289200141312431, "Supraventricular extrasystoles ": 2.0136786817885395, "Tachyphrenia ": 2.5554383542128964, "Talipes ": 5.520231839178042, "Tardive dyskinesia ": 23.68293687485168, "Tension ": 2.702980224401572, "Thinking abnormal ": 4.172988788802751, "Thirst ": 2.762738917279277, "Thrombocytosis ": 2.285253523483035, "Tinea pedis ": 6.813225132136809, "Torticollis ": 4.791621878891849, "Toxicity to various agents ": 2.044255622616792, "Transaminases increased ": 2.405450244904582, "Trismus ": 2.063182590581448, "Type 1 diabetes mellitus ": 14.301828932237015, "Type 2 diabetes mellitus ": 34.115576957815925, "Urinary hesitation ": 10.658317809607908, "Urinary incontinence ": 3.379143310864157, "Urinary retention ": 2.6311103210662243, "Vascular dementia ": 7.412748895653999, "Water intoxication ": 22.635089173349705, "Weight increased ": 19.36424138424285, "White blood cell count increased ": 2.9695551534584075, "Withdrawal syndrome ": 2.3421312800579845, "Wrong patient received product ": 2.4635423448112053}
\ No newline at end of file
+{"Alanine aminotransferase increased": 5.861718054897056, "Alopecia": 4.760617450716126, "Aspartate aminotransferase increased": 5.417595901406393, "Eczema": 10.35389393301356, "Gamma-glutamyltransferase increased": 6.332316417040714, "Liver function test increased": 16.158964072406498, "Multiple sclerosis": 20.702358230624483, "Multiple sclerosis relapse": 147.53093478950782, "Psoriasis": 5.849242037953012, "Rash": 2.5002246744869456, "Urinary tract infection": 4.419242063856719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1215.json
index 9293477d72a..2d59e47b0b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1215.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.921495966485069, "Cardiac failure ": 8.675111561641678, "Constipation ": 3.130077438763096, "Drug interaction ": 7.829372144369054, "Hypokalaemia ": 31.003792064069334, "Hyponatraemia ": 7.082231516235132, "Prostate cancer ": 19.69964984498989, "Rhabdomyolysis ": 11.56432057170765}
\ No newline at end of file
+{"Clostridium difficile infection": 798.4585521068532, "Drug ineffective": 12.315259380544996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1216.json
index b96d4ac6e1c..b5cdc7fbad0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1216.json
@@ -1 +1 @@
-{"5-hydroxyindolacetic acid increased ": 14.313118104890432, "Abdominal rebound tenderness ": 2.395793498914625, "Abdominal tenderness ": 2.0651347866368277, "Abdominal wall anomaly ": 3.5626190555644883, "Abdominal wall haematoma ": 4.09094865253149, "Abnormal behaviour ": 2.1795503744548177, "Abnormal dreams ": 2.080384359713867, "Abnormal labour ": 4.269330168075982, "Abnormal palmar/plantar creases ": 3.9327400336564944, "Abnormal sleep-related event ": 2.236525450824806, "Abortion ": 2.3734057252690675, "Abortion incomplete ": 2.6575345329485165, "Abortion induced incomplete ": 65.16459095163641, "Abortion threatened ": 2.439933410514347, "Abulia ": 2.649708048519545, "Accelerated idioventricular rhythm ": 4.02283837449332, "Accessory cardiac pathway ": 2.2142953271576955, "Accidental device ingestion ": 8.254122559732778, "Accidental exposure to product ": 2.7179768189468825, "Accidental exposure to product by child ": 5.137167934321396, "Accidental exposure to product packaging ": 2.23656444563837, "Accidental overdose ": 4.627073048447862, "Accidental poisoning ": 3.902382049098631, "Accommodation disorder ": 3.049082258947944, "Acid base balance abnormal ": 2.486041568829552, "Acid-base balance disorder mixed ": 2.387804269380746, "Acidosis ": 2.8382245636667927, "Acquired oesophageal web ": 4.355173022300543, "Acquired pigmented retinopathy ": 6.297862414159445, "Acromegaly ": 4.949096273395504, "Activation syndrome ": 6.294233900142147, "Acute chest syndrome ": 2.660559239224512, "Acute generalised exanthematous pustulosis ": 6.349263987112983, "Acute hepatic failure ": 2.3629281803631894, "Acute kidney injury ": 2.171205905176986, "Acute myopia ": 7.560962273187651, "Acute phosphate nephropathy ": 2.1983590768470163, "Acute promyelocytic leukaemia ": 2.0273906677297657, "Adactyly ": 3.524007618038884, "Adams-Stokes syndrome ": 8.553946467711636, "Adenoidal hypertrophy ": 2.5360437193186063, "Adenoidectomy ": 2.3318466652000325, "Adenoiditis ": 2.0464318866351654, "Adjustment disorder with mixed disturbance of emotion and conduct ": 2.848173647013041, "Administration site discolouration ": 2.140036938623944, "Administration site extravasation ": 10.12488604992442, "Administration site irritation ": 7.533176267607137, "Administration site phlebitis ": 3.77657001277882, "Adrenal suppression ": 2.2281594077974782, "Adrenergic syndrome ": 2.8576095853763683, "Adulterated product ": 2.0638454372262287, "Aggression ": 2.6931713507479467, "Agitation ": 2.778574409854176, "Agitation neonatal ": 3.78355831096998, "Agitation postoperative ": 2.5460556445726743, "Agonal death struggle ": 2.1487608395327937, "Agonal rhythm ": 2.2450342229325893, "Agoraphobia ": 2.004823590841542, "Agranulocytosis ": 4.927088453389699, "Air embolism ": 3.175990198234768, "Airway complication of anaesthesia ": 2.9603906551004995, "Akinesia ": 2.399516099169364, "Albumin urine ": 2.387804269380746, "Alcohol abuse ": 2.790836913623908, "Alcohol interaction ": 3.836258269526734, "Alcohol intolerance ": 2.379010938841997, "Alcohol poisoning ": 3.4895729379752813, "Alcohol use ": 2.1867888567417912, "Aldolase increased ": 3.448287030836279, "Alice in wonderland syndrome ": 2.0495228807388, "Alkalosis ": 2.743087324668022, "Alkalosis hypokalaemic ": 2.936222849208289, "Allergic reaction to excipient ": 3.3892999561922634, "Allergic stomatitis ": 3.442779540174401, "Allergy test negative ": 3.9689408540697295, "Allergy test positive ": 9.463109291441148, "Altered state of consciousness ": 2.9394888581026146, "Amblyopia ": 2.44932772245501, "Ameloblastoma ": 4.492837504195562, "Ammonia abnormal ": 2.508763467269691, "Ammonia increased ": 2.3577383602278457, "Amniotic band syndrome ": 2.2843330867299185, "Amniotic cavity disorder ": 4.300975156186353, "Amniotic fluid index abnormal ": 3.442779540174401, "Amniotic fluid volume decreased ": 2.1268714758691285, "Amniotic infection syndrome of Blane ": 2.5907254632306738, "Anaemia megaloblastic ": 2.966863723380408, "Anaesthesia oral ": 2.147345400553251, "Anaesthetic complication ": 8.11981345920038, "Anal atresia ": 2.899146497746764, "Anal incontinence ": 2.018061518334978, "Anal sphincter atony ": 2.2651680013742945, "Analgesic drug level increased ": 6.628258560056476, "Anaphylactic reaction ": 2.5056977790544943, "Anaphylactic shock ": 6.62077176035986, "Anaphylactoid reaction ": 5.107694725197075, "Anaphylactoid shock ": 5.730523357847515, "Anaphylactoid syndrome of pregnancy ": 2.7785219446407257, "Androgen deficiency ": 4.114099390788256, "Androgens abnormal ": 3.792326896754684, "Anger ": 2.37083254902094, "Angioedema ": 3.72060064163402, "Angiogram cerebral abnormal ": 2.119843710264686, "Angiotensin converting enzyme inhibitor foetopathy ": 12.43575419658052, "Angle closure glaucoma ": 7.209278183284273, "Anhidrosis ": 2.434915845771003, "Anion gap increased ": 2.167810359253016, "Anisocoria ": 2.114220728310066, "Anomalous pulmonary venous connection ": 4.819314099548674, "Anomaly of external ear congenital ": 4.347186733757916, "Anorgasmia ": 4.817993371418747, "Antasthmatic drug level above therapeutic ": 10.123542394551846, "Anterior chamber fibrin ": 5.177702854182607, "Anterior chamber inflammation ": 2.3000034235670075, "Anterior chamber pigmentation ": 6.249107449882757, "Anti factor VIII antibody positive ": 2.126420140360335, "Anti-erythropoietin antibody ": 2.8918101261397577, "Anti-erythropoietin antibody negative ": 2.0206059268522774, "Anti-erythropoietin antibody positive ": 2.472424226495301, "Anti-neutrophil cytoplasmic antibody positive vasculitis ": 2.4171275984934173, "Antibiotic associated colitis ": 4.627060647228294, "Antibiotic level above therapeutic ": 9.647693326596746, "Antibiotic level below therapeutic ": 2.738922347820625, "Anticholinergic syndrome ": 2.6037678651474696, "Anticoagulant-related nephropathy ": 13.257198417882725, "Anticoagulation drug level above therapeutic ": 5.7675993332376985, "Anticoagulation drug level below therapeutic ": 3.442512862192141, "Anticonvulsant drug level abnormal ": 3.884878719463113, "Anticonvulsant drug level above therapeutic ": 4.267365141095341, "Anticonvulsant drug level below therapeutic ": 4.168703922756898, "Anticonvulsant drug level decreased ": 6.537895630009107, "Anticonvulsant drug level increased ": 5.135149256780477, "Antidepressant discontinuation syndrome ": 3.636371078044172, "Antidepressant drug level above therapeutic ": 3.967075970378113, "Antidepressant drug level below therapeutic ": 4.802594096429057, "Antidepressant drug level increased ": 5.497939411714516, "Antidiuretic hormone abnormality ": 2.882650336471254, "Antipsychotic drug level above therapeutic ": 6.304581907039694, "Antipsychotic drug level decreased ": 3.6736587314690303, "Antipsychotic drug level increased ": 6.679057747235033, "Antisocial behaviour ": 4.741994668750362, "Anuria ": 2.6178249325926988, "Aorta hypoplasia ": 3.037725845126247, "Aortic valve atresia ": 2.2450342229325893, "Aortic valve incompetence ": 2.37342960392887, "Aortic wall hypertrophy ": 2.739337169947462, "Aortitis ": 2.393703955661359, "Apgar score low ": 2.59331698936654, "Aplasia cutis congenita ": 8.80848717857811, "Apnoea ": 2.998305437336556, "Appendix cancer ": 5.228685282958513, "Application site abscess ": 2.037812422706561, "Application site acne ": 8.45167466525154, "Application site alopecia ": 3.791598180341608, "Application site burn ": 11.906851381874386, "Application site dermatitis ": 8.637843294500454, "Application site discharge ": 3.2487421000399466, "Application site discolouration ": 10.273378247491229, "Application site discomfort ": 7.208495727880573, "Application site dryness ": 41.06112461163088, "Application site eczema ": 7.192783404900978, "Application site erosion ": 7.26020539786171, "Application site erythema ": 3.1756403525679224, "Application site exfoliation ": 16.49450891866841, "Application site extravasation ": 11.135564435826042, "Application site folliculitis ": 4.010584589699205, "Application site haemorrhage ": 2.011579604917944, "Application site hypersensitivity ": 8.363043486911334, "Application site infection ": 3.304367878880804, "Application site inflammation ": 6.472640969371964, "Application site irritation ": 15.773994281436265, "Application site laceration ": 4.617604539187664, "Application site mass ": 2.7785219446407257, "Application site necrosis ": 4.554081806157254, "Application site odour ": 2.562402753033977, "Application site oedema ": 2.1124970914036787, "Application site papules ": 11.386139095903053, "Application site paraesthesia ": 9.833986126933397, "Application site photosensitivity reaction ": 2.2142953271576955, "Application site plaque ": 6.966216456354185, "Application site pruritus ": 8.857872411016452, "Application site pustules ": 4.261048660632532, "Application site rash ": 13.550628420921498, "Application site scab ": 2.8748535685179606, "Application site scar ": 13.602521812653652, "Application site ulcer ": 2.373810070128011, "Application site urticaria ": 12.755959937088909, "Application site vesicles ": 7.226662435139376, "Application site warmth ": 3.661475534210249, "Application site wound ": 4.109071196305052, "Aqueous fibrin ": 8.782520890325227, "Arachnodactyly ": 17.88498050344945, "Areflexia ": 2.1124531043519053, "Arnold-Chiari malformation ": 4.2896695402129, "Arrested labour ": 3.657729150466252, "Arterial insufficiency ": 2.1614517302000533, "Arterial restenosis ": 2.0528597347076776, "Arterial therapeutic procedure ": 2.0344411705489893, "Arteriospasm coronary ": 4.164066145162414, "Artificial crown procedure ": 2.039414910660589, "Asphyxia ": 3.394039828224976, "Assisted suicide ": 4.007036161400551, "Asterixis ": 3.28877564799773, "Asthmatic crisis ": 2.775888565712766, "Astigmatism ": 2.3834058851159496, "Ataxia ": 2.9230026521847443, "Atelectasis neonatal ": 3.8062365289207896, "Atheroembolism ": 2.208597383915884, "Athetosis ": 2.90035005239272, "Atrial conduction time prolongation ": 3.787364818909382, "Atrial hypertrophy ": 2.59950973928883, "Atrial septal defect ": 6.294432837684384, "Atrioventricular block ": 3.1220676030718284, "Atrioventricular block complete ": 3.4066641739005794, "Atrioventricular block first degree ": 3.3095953342670037, "Atrioventricular block second degree ": 2.451064112069192, "Atrioventricular dissociation ": 4.321368662114901, "Attention deficit hyperactivity disorder ": 4.559624596490248, "Autism spectrum disorder ": 8.856395948699529, "Azoospermia ": 4.27009467894008, "BRASH syndrome ": 2.5855824849966824, "Ballismus ": 2.3710324922897565, "Barrett's oesophagus ": 2.624166962657097, "Bartter's syndrome ": 6.106621335564846, "Base excess decreased ": 2.0933226683496997, "Base excess negative ": 2.5044046076704296, "Behaviour disorder ": 2.802126672761681, "Belligerence ": 2.0895536841468973, "Benign breast neoplasm ": 2.023146762353026, "Benign congenital hypotonia ": 5.198964971256344, "Benzodiazepine drug level increased ": 2.8246314187502346, "Bereavement ": 3.5148518229747605, "Bezoar ": 5.630591657227035, "Bicuspid aortic valve ": 8.263762588330993, "Bilirubinuria ": 2.2306810060740507, "Biopsy brain abnormal ": 9.224438259435836, "Biopsy breast ": 3.133680745964011, "Biopsy breast abnormal ": 11.077732316375805, "Biopsy colon abnormal ": 7.989991806006669, "Biopsy endometrium ": 4.1423793880704975, "Biopsy endometrium abnormal ": 2.7324561440655404, "Biopsy mucosa abnormal ": 3.0938723142390154, "Biopsy prostate ": 2.119843710264686, "Biopsy skin ": 2.779548869789919, "Biopsy skin abnormal ": 3.191864984008677, "Bipolar II disorder ": 2.9785366220926184, "Bipolar disorder ": 2.095435750385965, "Birth trauma ": 2.4815607600334006, "Bite ": 2.101633699983286, "Bladder cancer ": 9.444506687852456, "Bladder cancer stage II ": 2.739337169947462, "Bladder cancer stage III ": 2.5322569562112758, "Bladder cancer stage IV ": 2.4172669215511355, "Bladder dilatation ": 2.4644238263318696, "Bladder necrosis ": 9.151157299211915, "Bladder perforation ": 2.1222868188317268, "Blister rupture ": 2.046410553472152, "Blood 1,25-dihydroxycholecalciferol increased ": 2.158702033383775, "Blood 25-hydroxycholecalciferol increased ": 3.77657001277882, "Blood acid phosphatase increased ": 2.158702033383775, "Blood alcohol increased ": 3.5145677090731966, "Blood aldosterone increased ": 2.771171487222005, "Blood alkaline phosphatase increased ": 2.1058511218659026, "Blood aluminium increased ": 2.415129997857277, "Blood antidiuretic hormone decreased ": 2.387804269380746, "Blood antidiuretic hormone increased ": 2.831712131471681, "Blood bicarbonate decreased ": 2.0747068772987305, "Blood catecholamines increased ": 2.3523687945817944, "Blood cholinesterase decreased ": 3.106548277458922, "Blood cholinesterase increased ": 2.0954861709124013, "Blood chromogranin A increased ": 2.467786338083004, "Blood creatine phosphokinase ": 2.569455383556475, "Blood creatine phosphokinase increased ": 2.801613084082044, "Blood follicle stimulating hormone decreased ": 4.060989426796331, "Blood glucose false positive ": 7.408067933199498, "Blood growth hormone abnormal ": 4.422873492092894, "Blood growth hormone decreased ": 2.1110273354908933, "Blood growth hormone increased ": 4.254257869355732, "Blood lactic acid decreased ": 2.1497644818720323, "Blood luteinising hormone decreased ": 3.3811543937641435, "Blood mercury abnormal ": 8.826875229204319, "Blood oestrogen decreased ": 3.087517880022931, "Blood oestrogen increased ": 3.71263744014569, "Blood osmolarity decreased ": 3.5759889551906507, "Blood pressure decreased ": 2.328870092474373, "Blood pressure immeasurable ": 4.970459086487663, "Blood pressure inadequately controlled ": 3.7565980554356257, "Blood pressure orthostatic ": 2.992924724076415, "Blood prolactin increased ": 2.560482093641748, "Blood sodium decreased ": 2.038708358154325, "Blood sodium increased ": 2.1254556562260185, "Blood testosterone abnormal ": 2.7371621301886218, "Blood testosterone decreased ": 3.791160273071851, "Blood testosterone free decreased ": 3.4119142571515, "Blood testosterone increased ": 3.5997300350910018, "Blood urea increased ": 2.4067656008320184, "Bloody peritoneal effluent ": 6.8031563798956105, "Blunted affect ": 2.9558649782108204, "Body dysmorphic disorder ": 2.187165700215114, "Body height abnormal ": 2.05052867485809, "Body height decreased ": 2.3283573946524942, "Bone development abnormal ": 2.194682658719877, "Bone hyperpigmentation ": 12.348584906471904, "Bone marrow granuloma ": 5.879276102958377, "Brachial artery entrapment syndrome ": 4.000509736211133, "Brachycephaly ": 2.3725271003843598, "Brachydactyly ": 4.121242872845213, "Bradyarrhythmia ": 4.531337811583909, "Bradycardia ": 4.139522565604644, "Bradycardia foetal ": 2.6375230386540083, "Bradycardia neonatal ": 4.860418217932575, "Bradyphrenia ": 2.202819665104296, "Bradypnoea ": 7.390258809427916, "Brain injury ": 2.141691015596323, "Brain neoplasm malignant ": 3.425980426871486, "Breast calcifications ": 4.254321323894745, "Breast cancer ": 5.389194160530513, "Breast cancer female ": 3.612261894267164, "Breast cancer in situ ": 2.5201459396265244, "Breast cancer male ": 5.793712599498985, "Breast cancer metastatic ": 2.017743264265305, "Breast conserving surgery ": 3.145446526419118, "Breast discolouration ": 2.0174289351687524, "Breast feeding ": 2.509729990345664, "Breast fibrosis ": 2.079574660946283, "Breast hyperplasia ": 2.9400792309141184, "Breast malformation ": 2.8888362465479496, "Breast necrosis ": 5.083191106119852, "Breast reconstruction ": 2.80330718380949, "Breath alcohol test positive ": 8.782520890325227, "Breathing-related sleep disorder ": 2.1222868188317268, "Brief resolved unexplained event ": 2.0210695270957983, "Bromoderma ": 2.119843710264686, "Bronchial oedema ": 2.216280710420783, "Bronchomalacia ": 2.4815607600334006, "Bronchospasm ": 4.0409257328201145, "Bronchospasm paradoxical ": 7.23983070600359, "Bronchostenosis ": 3.3430720110221044, "Brugada syndrome ": 5.941825469695847, "Bruxism ": 2.700617782461273, "Bundle branch block ": 3.6321815932817008, "Bundle branch block right ": 2.385101126991965, "Burkholderia cepacia complex infection ": 2.34264995267084, "Burn oesophageal ": 4.645521309575196, "Burn oral cavity ": 3.643316454604004, "Burning sensation mucosal ": 2.8583683741825903, "Burns first degree ": 2.3454861914388463, "CSWS syndrome ": 4.1423793880704975, "Calciphylaxis ": 6.153934836026213, "Camptodactyly congenital ": 9.338023666888736, "Cannabinoid hyperemesis syndrome ": 3.774620949352752, "Carbon monoxide poisoning ": 2.412726658986069, "Carcinogenicity ": 16.412066977322873, "Cardiac arrest ": 2.655410469420524, "Cardiac arrest neonatal ": 4.153486078936919, "Cardiac massage ": 5.6671013587265735, "Cardiac murmur ": 2.594658844746046, "Cardiac pacemaker removal ": 2.2796882444559303, "Cardiac steatosis ": 2.0443614718434326, "Cardiac valve sclerosis ": 2.936222849208289, "Cardio-respiratory arrest ": 3.237164246953241, "Cardio-respiratory arrest neonatal ": 7.461888341814831, "Cardio-respiratory distress ": 2.03937860268986, "Cardioactive drug level above therapeutic ": 5.896547399339858, "Cardioactive drug level decreased ": 16.298584399143117, "Cardioactive drug level increased ": 16.37503001983234, "Carnitine decreased ": 2.1384046678205544, "Carnitine deficiency ": 4.198178255655119, "Carotid bruit ": 2.002485545933019, "Cataract congenital ": 2.942808161658988, "Catecholamines urine increased ": 2.693428309169082, "Catheter site discharge ": 2.026050891556175, "Catheter site erythema ": 2.0934306015453608, "Catheter site extravasation ": 3.52619349075127, "Catheter site urticaria ": 2.158702033383775, "Catheter site warmth ": 2.844207717923794, "Cauda equina syndrome ": 2.452575989619478, "Central auditory processing disorder ": 2.792889305099717, "Central nervous system stimulation ": 2.7985964375096817, "Central venous catheter removal ": 2.3694819820917625, "Central venous pressure decreased ": 2.4603171588385395, "Cerebellar ataxia ": 2.802600716165156, "Cerebellar atrophy ": 5.39611190431455, "Cerebellar hypoplasia ": 2.1366854047680577, "Cerebellar syndrome ": 2.525140640427933, "Cerebral atrophy ": 2.077087126163156, "Cerebral haemorrhage neonatal ": 2.5913256838914767, "Cerebral palsy ": 3.2265559738765006, "Cerebral vasoconstriction ": 2.2614637581272605, "Cerebral ventricle dilatation ": 2.7804684864385405, "Cervix carcinoma ": 2.261405827013813, "Cervix erythema ": 2.2142953271576955, "Chemical burn ": 7.515696281640654, "Chemical burn of oral cavity ": 4.143453142560489, "Chemical burn of respiratory tract ": 6.389045994236043, "Chemical burn of skin ": 5.5697481350599, "Chemical burns of eye ": 4.64777118174146, "Chemical cystitis ": 4.362431881502759, "Chemical phlebitis ": 8.0694678103627, "Chemical poisoning ": 2.670761264030718, "Chemical submission ": 2.411107289406896, "Cheyne-Stokes respiration ": 3.2576093592163944, "Chloasma ": 2.6900865223538863, "Choanal atresia ": 11.146063429893132, "Choking ": 3.126424088601889, "Choking sensation ": 3.0760840808994314, "Cholecystitis chronic ": 2.6672259111164243, "Cholestasis ": 2.4045497871051054, "Cholestatic liver injury ": 2.729866538516206, "Cholinergic syndrome ": 7.848200124263555, "Chordee ": 3.952252586488466, "Chorea ": 2.784908498041033, "Choreoathetosis ": 4.159022771896933, "Choroidal detachment ": 2.314194629978571, "Choroidal effusion ": 4.766080694878947, "Choroidal haemorrhage ": 4.496029359065561, "Chromaturia ": 2.1664074045570194, "Chronic hepatitis ": 2.4014421886678017, "Chronic obstructive pulmonary disease ": 2.026162680032986, "Chronotropic incompetence ": 3.0331553627838432, "Ciliary body disorder ": 3.4827677595506565, "Circulatory collapse ": 2.7545207384561903, "Circulatory failure neonatal ": 5.896547399339858, "Circumoral oedema ": 2.3716620455582684, "Circumstance or information capable of leading to device use error ": 2.060661229853793, "Circumstance or information capable of leading to medication error ": 2.5577816871447627, "Cleft lip ": 5.703858760757484, "Cleft lip and palate ": 3.878848062167914, "Cleft palate ": 5.674994930699225, "Cleft uvula ": 9.669067686204542, "Clinodactyly ": 5.316568274859348, "Clonic convulsion ": 2.655065787714786, "Clonus ": 2.27001975433668, "Clostridium colitis ": 2.798541905095965, "Clostridium difficile colitis ": 2.883645983708645, "Clostridium test positive ": 4.911122106780358, "Coagulation disorder neonatal ": 4.843626274582155, "Coagulation factor VII level decreased ": 2.4593523396094774, "Coagulation factor X level decreased ": 2.4950645103913405, "Coagulation factor decreased ": 2.9922010652665, "Coagulation test abnormal ": 2.113757246688267, "Coagulation time prolonged ": 4.0760177509932, "Coarctation of the aorta ": 7.639110905941137, "Coating in mouth ": 2.1632652325959785, "Cogwheel rigidity ": 2.2647010133458605, "Coloboma ": 2.142297341711985, "Colon cancer stage III ": 2.2246305539333093, "Colonic haematoma ": 2.4699264535838386, "Colonoscopy abnormal ": 3.5070305741311985, "Colony stimulating factor therapy ": 6.569142317722045, "Colorectal cancer ": 38.24214475571569, "Colorectal cancer stage I ": 5.992219891988702, "Colorectal cancer stage II ": 8.713709740761487, "Colorectal cancer stage III ": 4.483532431141876, "Colorectal cancer stage IV ": 2.449885637549513, "Colour vision tests abnormal ": 2.0732840918983566, "Coma ": 3.829866379483963, "Coma scale abnormal ": 2.909522303514924, "Communication disorder ": 2.6773233778093104, "Compartment syndrome ": 2.374626704888929, "Compensatory sweating ": 2.4172669215511355, "Completed suicide ": 5.35933710347481, "Complication associated with device ": 2.072931298625923, "Complication of delivery ": 2.260133068938337, "Complication of device insertion ": 3.839552982777063, "Complication of device removal ": 2.5460556445726743, "Compulsions ": 2.883764207588273, "Compulsive lip biting ": 2.848173647013041, "Conduction disorder ": 3.3687532136732954, "Congenital absence of bile ducts ": 2.259521014279036, "Congenital anomaly ": 3.2704689230368134, "Congenital anomaly in offspring ": 4.186724206320195, "Congenital aortic anomaly ": 2.1436111746495685, "Congenital aortic atresia ": 6.340477532119922, "Congenital aortic stenosis ": 12.130823781918492, "Congenital aortic valve incompetence ": 6.779355604401743, "Congenital aortic valve stenosis ": 11.966320698973249, "Congenital brain damage ": 4.893452046139301, "Congenital cardiovascular anomaly ": 13.091129553352667, "Congenital central nervous system anomaly ": 3.823610935757082, "Congenital cerebellar agenesis ": 4.843626274582155, "Congenital cerebral cyst ": 3.257312499748678, "Congenital coronary artery malformation ": 3.0519610348856903, "Congenital cyst ": 3.9817214600888367, "Congenital cystic kidney disease ": 2.7765584584197787, "Congenital diaphragmatic hernia ": 2.211141489254409, "Congenital eye disorder ": 5.214905144521248, "Congenital eyelid malformation ": 3.3592250169510494, "Congenital facial diplegia ": 6.718693413790624, "Congenital flat feet ": 6.142822436292995, "Congenital foot malformation ": 6.074003366358169, "Congenital genital malformation ": 2.263628304330927, "Congenital genital malformation male ": 3.018048574023795, "Congenital genitourinary abnormality ": 5.8435418733158135, "Congenital hand malformation ": 10.220279849209668, "Congenital hearing disorder ": 2.091528472676385, "Congenital heart valve disorder ": 6.915373319994121, "Congenital hydrocephalus ": 2.842235623081669, "Congenital hydronephrosis ": 2.1532386717524585, "Congenital hypothyroidism ": 5.924204865755229, "Congenital inguinal hernia ": 4.745736607642976, "Congenital jaw malformation ": 4.960764579439824, "Congenital knee deformity ": 2.951985109345318, "Congenital laryngeal stridor ": 2.119843710264686, "Congenital megacolon ": 2.7893707053248438, "Congenital megaureter ": 4.855175014559221, "Congenital mitral valve incompetence ": 4.577231279559243, "Congenital mitral valve stenosis ": 4.362431881502759, "Congenital multiplex arthrogryposis ": 3.076441908714847, "Congenital musculoskeletal disorder ": 3.078906456131421, "Congenital musculoskeletal disorder of limbs ": 7.184964465072198, "Congenital musculoskeletal disorder of skull ": 5.490266935379341, "Congenital musculoskeletal disorder of spine ": 3.161596924363436, "Congenital nail disorder ": 6.665797604505982, "Congenital neurological disorder ": 7.161141226200562, "Congenital nose malformation ": 8.97628505553988, "Congenital nystagmus ": 9.529860179479076, "Congenital oesophageal anomaly ": 2.848173647013041, "Congenital oral malformation ": 6.423967744863229, "Congenital pulmonary artery anomaly ": 10.133268100153286, "Congenital pulmonary hypertension ": 7.597558212164849, "Congenital pulmonary valve atresia ": 6.858535438694921, "Congenital pulmonary valve disorder ": 3.87893833691815, "Congenital renal disorder ": 3.720001388026715, "Congenital scoliosis ": 10.342615192874046, "Congenital skin dimples ": 2.226066968827946, "Congenital spinal cord anomaly ": 3.178702039398656, "Congenital syphilis ": 3.178702039398656, "Congenital tongue anomaly ": 3.5716248259132075, "Congenital torticollis ": 4.986923166446594, "Congenital tricuspid valve atresia ": 7.815999491952704, "Congenital tricuspid valve incompetence ": 2.3242317539059485, "Congenital urethral anomaly ": 2.946876774685152, "Congenital uterine anomaly ": 2.3778832419943305, "Congenital visual acuity reduced ": 7.580088704520082, "Conjunctival bleb ": 3.363071307471851, "Conjunctival cyst ": 2.5322569562112758, "Conjunctival deposit ": 3.615082672656949, "Conjunctival discolouration ": 2.635913811003926, "Conjunctival erosion ": 3.01474544380596, "Conjunctival filtering bleb leak ": 21.41468065131837, "Conjunctival hyperaemia ": 3.261581592645924, "Conjunctival oedema ": 3.5577112047649333, "Conjunctival ulcer ": 2.8166190633714923, "Consciousness fluctuating ": 2.6895067915123465, "Contact lens intolerance ": 5.872848245864311, "Contraindicated product prescribed ": 3.4772974339163, "Contraindication to medical treatment ": 3.5446371750639747, "Contrast media reaction ": 5.8427672306832825, "Contrast media toxicity ": 2.182707492679382, "Convulsions local ": 5.902802252869302, "Coombs direct test positive ": 2.1019569977481214, "Coprolalia ": 2.59950973928883, "Cord blood transplant therapy ": 3.018048574023795, "Cornea verticillata ": 2.23656444563837, "Corneal abrasion ": 2.1927608750352383, "Corneal degeneration ": 2.3242317539059485, "Corneal deposits ": 6.317827000882044, "Corneal disorder ": 2.705621617436817, "Corneal epithelium defect ": 3.0279207656230938, "Corneal erosion ": 2.9451976209850206, "Corneal infiltrates ": 2.508694369401621, "Corneal oedema ": 3.5397183472182707, "Corneal opacity ": 2.7483156997789377, "Corneal pigmentation ": 2.1706108345009483, "Coronary angioplasty ": 5.477499009509459, "Corpora cavernosa surgery ": 35.92416861404185, "Cotard's syndrome ": 2.059807064143012, "Craniofacial deformity ": 8.82757320125621, "Craniopharyngioma ": 5.236119233706769, "Craniosynostosis ": 15.750694915829232, "Crime ": 2.141940521401468, "Cross sensitivity reaction ": 5.287401002199151, "Crush syndrome ": 2.5460556445726743, "Crying ": 2.015615364465544, "Cryptorchism ": 3.845950705645684, "Crystal deposit intestine ": 3.6909512834391984, "Crystal nephropathy ": 2.4389865954265604, "Crystalluria ": 3.135090396078424, "Cutis laxa ": 2.154150020697041, "Cyanosis ": 2.958375563029909, "Cyanosis central ": 2.8695673302871256, "Cyanosis neonatal ": 4.442290807349576, "Cyclothymic disorder ": 2.863469777983985, "Cytogenetic abnormality ": 2.4205435959050567, "Dacryostenosis acquired ": 3.992785387049844, "Dacryostenosis congenital ": 3.8654239520323976, "Dandruff ": 4.985036164393428, "Deafness congenital ": 2.579042981685236, "Death neonatal ": 2.0167291437154518, "Decompensated hypothyroidism ": 4.122521220703462, "Decorticate posture ": 2.431575004969513, "Defect conduction intraventricular ": 2.4852296067555475, "Defiant behaviour ": 3.1582598847212897, "Deformity thorax ": 2.7599328232409817, "Delayed fontanelle closure ": 2.0464318866351654, "Delayed recovery from anaesthesia ": 4.414367719550118, "Delirium ": 2.108173550945074, "Delirium tremens ": 2.289587896539256, "Delusion ": 2.129155449540047, "Delusional disorder, unspecified type ": 2.20912144544718, "Dementia Alzheimer's type ": 2.0523851731833904, "Dental plaque ": 2.1366854047680577, "Dentofacial anomaly ": 5.194688139804288, "Dependence ": 5.894619681387182, "Depersonalisation/derealisation disorder ": 3.5295148955274684, "Depilation ": 2.356026082357269, "Deposit eye ": 2.778568784081628, "Depressed level of consciousness ": 2.487718266299383, "Derealisation ": 2.444646997154896, "Dermal absorption impaired ": 9.529860179479076, "Dermatillomania ": 2.0186452439690656, "Dermatitis allergic ": 2.0055263816926483, "Dermatitis bullous ": 2.450141480073126, "Dermatitis contact ": 3.5607244408422694, "Dermatitis diaper ": 2.1444215425600053, "Dermatitis exfoliative ": 2.731070490524626, "Dermatitis exfoliative generalised ": 2.849320693544969, "Developmental coordination disorder ": 12.617776279756622, "Developmental delay ": 6.400478729412912, "Developmental hip dysplasia ": 2.425933965096201, "Developmental regression ": 2.468797304151005, "Device alarm issue ": 2.637673923603099, "Device allergy ": 2.3778832419943305, "Device breakage ": 2.039619468907754, "Device capturing issue ": 3.787364818909382, "Device colour issue ": 3.99137987232265, "Device connection issue ": 2.8178149482102506, "Device delivery system issue ": 3.2405284963705507, "Device dispensing error ": 2.415129997857277, "Device expulsion ": 2.156916737865857, "Device failure ": 3.9669781721215625, "Device ineffective ": 8.10471951408704, "Device infusion issue ": 3.057660323197817, "Device malfunction ": 2.2658046580962816, "Device material issue ": 2.05052867485809, "Device pacing issue ": 8.518300179610732, "Device physical property issue ": 2.5249763183370035, "Device placement issue ": 3.1582598847212897, "Device power source issue ": 4.717673034412784, "Device programming error ": 8.413232666285767, "Device safety feature issue ": 4.705583054188087, "Device toxicity ": 4.406448101978552, "Device use error ": 4.719271362286081, "Device use issue ": 2.5091401113766705, "Dextrocardia ": 4.386797935305641, "DiGeorge's syndrome ": 3.0265595087464576, "Diabetes insipidus ": 2.7536556613705887, "Diagnostic procedure ": 2.654715123360537, "Diaphragmatic paralysis ": 2.0212289754145263, "Dihydrotestosterone decreased ": 6.78597621727484, "Dilatation ventricular ": 3.2233667657231773, "Disorganised speech ": 2.003948003577824, "Disorientation ": 2.1165285530674067, "Dissociation ": 2.373132342606381, "Dissociative disorder ": 2.7194376992975915, "Distributive shock ": 3.37537800876425, "Disturbance in sexual arousal ": 3.8228199897022175, "Diverticulum ": 4.010707104851753, "Diverticulum intestinal ": 4.497157838323047, "Diverticulum oesophageal ": 2.7801871827442293, "Documented hypersensitivity to administered product ": 10.625589676789732, "Dose calculation error ": 2.780840424534706, "Double outlet right ventricle ": 2.9195418840675096, "Drooling ": 2.388198772813209, "Drowning ": 2.0038374546137248, "Drug abuse ": 7.065219516060858, "Drug abuser ": 12.346806829450482, "Drug chemical incompatibility ": 12.201030850933437, "Drug delivery system issue ": 5.12370747165833, "Drug delivery system removal ": 4.570305539412523, "Drug dependence ": 5.892711789397809, "Drug dependence, antepartum ": 2.6556073102073143, "Drug diversion ": 4.189458598481271, "Drug dose omission by device ": 2.407482081097301, "Drug eruption ": 2.6447027181899867, "Drug interaction ": 2.56571895511184, "Drug level above therapeutic ": 3.955919432112195, "Drug level decreased ": 2.138355254123373, "Drug level fluctuating ": 3.2520925913554986, "Drug level increased ": 3.527409414526013, "Drug monitoring procedure incorrectly performed ": 3.68835493648122, "Drug monitoring procedure not performed ": 2.499286384766875, "Drug reaction with eosinophilia and systemic symptoms ": 3.893697904017204, "Drug rehabilitation ": 2.325722557999482, "Drug screen false positive ": 3.2034584186415667, "Drug specific antibody absent ": 2.538344019046156, "Drug therapeutic incompatibility ": 9.92549416813464, "Drug tolerance increased ": 3.078200487967968, "Drug use disorder ": 4.840316325346827, "Drug withdrawal convulsions ": 7.484072770518285, "Drug withdrawal headache ": 3.2927905000069786, "Drug withdrawal maintenance therapy ": 3.601654780680706, "Drug withdrawal syndrome ": 2.022715174889647, "Drug withdrawal syndrome neonatal ": 2.1841858823059424, "Drug-disease interaction ": 2.573367417528411, "Drug-induced liver injury ": 2.0975507988261084, "Ductus arteriosus premature closure ": 5.481454892736287, "Ductus arteriosus stenosis foetal ": 6.683113646453936, "Duplicate therapy error ": 3.933202838056386, "Dysaesthesia pharynx ": 12.772471136345011, "Dysarthria ": 2.146945856375951, "Dysbiosis ": 2.344158679059403, "Dyscalculia ": 3.7203553065899935, "Dysdiadochokinesis ": 2.617736458462352, "Dysgraphia ": 2.5887014094247687, "Dyskinesia ": 2.4554988461062046, "Dyskinesia neonatal ": 2.461877076965808, "Dyslalia ": 2.4533378158691965, "Dyslexia ": 3.499241884108153, "Dysmetria ": 2.832645681281876, "Dysmetropsia ": 3.5424778899304763, "Dysmorphism ": 11.838128282423618, "Dysphemia ": 2.2266635461189845, "Dyspraxia ": 4.620967182930328, "Dystonia ": 2.677968138049039, "Ear malformation ": 2.710195527047615, "Ear, nose and throat disorder ": 20.003002129228943, "Ebstein's anomaly ": 5.813785581687294, "Echolalia ": 4.91416801219962, "Eclampsia ": 3.944101558416704, "Ectopic pregnancy under hormonal contraception ": 4.087854129026545, "Ectrodactyly ": 2.270709421972378, "Educational problem ": 7.835082602018325, "Egocentrism ": 3.615082672656949, "Ejaculation delayed ": 3.060396797059034, "Ejaculation disorder ": 3.396604241994385, "Ejaculation failure ": 3.941122329958113, "Elastosis perforans ": 5.879276102958377, "Electrocardiogram P wave abnormal ": 2.6026397839377307, "Electrocardiogram PR prolongation ": 2.77772294951808, "Electrocardiogram QRS complex ": 2.1487608395327937, "Electrocardiogram QRS complex abnormal ": 2.2111223174168164, "Electrocardiogram QRS complex prolonged ": 7.245943164411023, "Electrocardiogram QRS complex shortened ": 5.469820429167827, "Electrocardiogram QT prolonged ": 2.521173385843104, "Electrocardiogram QT shortened ": 3.123254254014722, "Electrocardiogram ST segment abnormal ": 2.858006846205243, "Electrocardiogram ST segment depression ": 2.987554282438776, "Electrocardiogram ST segment elevation ": 2.168250195313933, "Electrocardiogram ST-T segment abnormal ": 2.7538219158768213, "Electrocardiogram ST-T segment depression ": 2.059807064143012, "Electrocardiogram T wave abnormal ": 2.080117867805221, "Electrocardiogram T wave amplitude decreased ": 2.2871112423576205, "Electrocardiogram T wave amplitude increased ": 3.4027766816184544, "Electrocardiogram T wave inversion ": 2.711743963238393, "Electrocardiogram T wave peaked ": 2.727197458792604, "Electrocardiogram U-wave abnormality ": 6.8031563798956105, "Electrocardiogram abnormal ": 2.135463740002004, "Electrocardiogram change ": 3.2273844410884927, "Electrocardiogram repolarisation abnormality ": 2.630327964366432, "Electroencephalogram abnormal ": 3.1477598554496407, "Embedded device ": 4.826380696809855, "Embolia cutis medicamentosa ": 6.854608928972396, "Emergency care ": 3.139681335515045, "Emergency care examination ": 6.326282897596922, "Emotional disorder ": 2.183317074436155, "Emotional disorder of childhood ": 2.037812422706561, "Emotional poverty ": 3.421834528426761, "Empty sella syndrome ": 4.406825286148448, "Enanthema ": 2.4848376641965126, "Encapsulating peritoneal sclerosis ": 3.183863684710422, "Encephalitis mumps ": 2.158702033383775, "Encephalomalacia ": 2.0331920372538743, "Encephalopathy ": 2.4090440867277128, "Encephalopathy neonatal ": 2.0495228807388, "Encopresis ": 6.122567086251918, "Endocardial fibroelastosis ": 3.018316396517281, "Endometrial disorder ": 3.5785656896673106, "Endometrial hyperplasia ": 2.300546978580927, "Endometrial thickening ": 2.144268970885839, "Endometritis ": 2.792561727127509, "Endotoxic shock ": 4.147715741662421, "Endotracheal intubation complication ": 2.940836801598202, "Enterocolitis haemorrhagic ": 2.188235192217729, "Enuresis ": 3.5410476536119364, "Environmental exposure ": 2.7144895211211426, "Eosinophilia ": 2.800096310678105, "Eosinophilic cystitis ": 2.792889305099717, "Eosinophilic granulomatosis with polyangiitis ": 2.8659241770403114, "Eosinophilic myocarditis ": 2.091186638446401, "Eosinophilic oesophagitis ": 3.326418747837527, "Eosinophilic pleural effusion ": 3.2627323947230757, "Eosinophilic pneumonia acute ": 2.0261695015722414, "Epidermal necrosis ": 2.114081631073484, "Epidermolysis bullosa ": 2.330291924802159, "Epididymal cyst ": 5.173761806797733, "Epiglottic oedema ": 2.4902575120634944, "Epilepsy ": 2.0959722503844254, "Epiphyseal disorder ": 6.249107449882757, "Epiphyses premature fusion ": 4.047972505381089, "Epiphysiolysis ": 4.130712470204268, "Erectile dysfunction ": 3.208301401869256, "Erosive duodenitis ": 2.5998609390397287, "Erosive oesophagitis ": 2.217156186107702, "Erythema multiforme ": 2.479546196814607, "Erythema of eyelid ": 2.135826209204301, "Erythropenia ": 2.837061924840992, "Erythrosis ": 2.0558291541649525, "Euphoric mood ": 2.0109994037351173, "Evacuation of retained products of conception ": 6.406470326786169, "Excessive sexual fantasies ": 3.487298748185552, "Executive dysfunction ": 4.214356309415495, "Exomphalos ": 3.629204653585501, "Expired device used ": 2.097026550916415, "Expired product administered ": 3.442835123113705, "Exposure to contaminated device ": 2.387043285011238, "Exposure to toxic agent ": 3.036245348071156, "Exposure via blood ": 4.802594096429057, "Exposure via eye contact ": 4.385314579180378, "Exposure via ingestion ": 4.397641702896371, "Exposure via inhalation ": 2.6974128087585774, "Expulsion of medication ": 10.338195159448963, "Extensor plantar response ": 3.22318629535282, "Extradural haematoma ": 2.0117790350714846, "Extrapyramidal disorder ": 2.5703932687781457, "Extravasation ": 4.223151899885759, "Eye complication associated with device ": 2.1487608395327937, "Eye degenerative disorder ": 2.387467590390321, "Eye infection intraocular ": 7.614347480759988, "Eye movement disorder ": 2.128595587028045, "Eye oedema ": 2.215526669831582, "Eyelid erosion ": 3.2191414182460285, "Eyelid oedema ": 2.852397454504708, "Eyelid ptosis congenital ": 3.109802340156836, "Face oedema ": 3.082956424073913, "Factor II deficiency ": 6.952804379260789, "Factor VII deficiency ": 2.654715123360537, "Faecal vomiting ": 2.125622382723944, "Faecaloma ": 2.816818709399569, "Faeces hard ": 2.038881743899592, "Faeces pale ": 2.5332242044362623, "Failed in vitro fertilisation ": 2.3793318554953204, "Fallot's tetralogy ": 8.99204728137524, "False negative investigation result ": 4.688436715608479, "False positive investigation result ": 2.0015339580178004, "Fat embolism ": 3.7005894790151976, "Fear ": 2.385596435484848, "Fear of death ": 2.165824618148924, "Fear of disease ": 3.5531329557506397, "Febrile convulsion ": 3.360910891301883, "Febrile nonhaemolytic transfusion reaction ": 2.5266024138001204, "Feeling jittery ": 2.254664772833481, "Feelings of worthlessness ": 3.484395605044972, "Female orgasmic disorder ": 3.571431063313624, "Female sexual dysfunction ": 3.3921150717170643, "Feminisation acquired ": 3.5148518229747605, "Femoral anteversion ": 2.3465532070172253, "Femoral artery dissection ": 2.387804269380746, "Femoral nerve palsy ": 4.743659412034792, "Fibrin degradation products increased ": 2.0373250893473926, "Fibrocystic breast disease ": 3.08188442077795, "Fibroma ": 2.059191488784373, "Fight in school ": 4.406448101978552, "Fine motor delay ": 5.756935901160102, "Fixed eruption ": 5.581241084105412, "Flap necrosis ": 4.802594096429057, "Flashback ": 2.519817039689048, "Flat anterior chamber of eye ": 5.896765777660648, "Flight of ideas ": 2.4710532678765573, "Floppy infant ": 2.284346863724446, "Floppy iris syndrome ": 9.18078064038258, "Fluid replacement ": 2.4793349669065576, "Flushing ": 2.3398926738851915, "Foaming at mouth ": 3.2259250312244188, "Foetal acidosis ": 3.1582598847212897, "Foetal alcohol syndrome ": 3.6147353771008457, "Foetal anticonvulsant syndrome ": 56.60793198935472, "Foetal arrhythmia ": 2.1596009473666915, "Foetal biophysical profile score abnormal ": 3.487298748185552, "Foetal damage ": 3.859879244102083, "Foetal disorder ": 2.061906266219399, "Foetal distress syndrome ": 2.021924147383038, "Foetal exposure during delivery ": 4.746941806689264, "Foetal exposure during pregnancy ": 3.4075454519191566, "Foetal exposure timing unspecified ": 2.540516527616836, "Foetal heart rate abnormal ": 2.1146288162081905, "Foetal heart rate decreased ": 2.932063811107728, "Foetal heart rate disorder ": 4.979405671064821, "Foetal heart rate increased ": 2.040534036553507, "Foetal monitoring abnormal ": 3.5304547010535843, "Foetal non-stress test abnormal ": 3.110179983811206, "Foetal warfarin syndrome ": 14.94675601383527, "Fontanelle bulging ": 2.0895536841468973, "Food interaction ": 3.44519585305426, "Foreign body aspiration ": 5.664074894467893, "Foreign body in gastrointestinal tract ": 3.112300009500563, "Foreign body in mouth ": 9.248258253748087, "Foreign body in respiratory tract ": 2.962524686275257, "Foreign body in throat ": 4.211819422326996, "Fracture of penis ": 18.168891145059757, "Fungal peritonitis ": 2.4949302428072717, "Galactorrhoea ": 4.228099880272463, "Gallbladder cancer ": 4.191688272364003, "Gambling ": 2.2942244644057808, "Gamma-glutamyltransferase increased ": 2.222497590153365, "Gastric cancer ": 8.347281463402279, "Gastric cancer stage IV ": 2.329282992563667, "Gastric lavage ": 4.688159595029086, "Gastric mucosa erythema ": 2.23731833874971, "Gastric mucosal hypertrophy ": 2.1497644818720323, "Gastric polyps ": 2.833022295722777, "Gastritis erosive ": 2.379954071165153, "Gastroenteritis staphylococcal ": 2.060661229853793, "Gastrointestinal carcinoma ": 5.897675203799092, "Gastrointestinal disorder congenital ": 2.1389058749145065, "Gastrointestinal malformation ": 2.0414027323249155, "Gastrointestinal sounds abnormal ": 2.406696308992664, "Gastrointestinal stoma output decreased ": 3.1548067533935624, "Gastrointestinal tract mucosal discolouration ": 2.154150020697041, "Gastrointestinal tract mucosal pigmentation ": 5.561076207242002, "Gastrooesophageal sphincter insufficiency ": 3.8425457006871793, "Gastroschisis ": 4.008083520529888, "Gaze palsy ": 2.948566669567294, "General anaesthesia ": 3.524007618038884, "Generalised bullous fixed drug eruption ": 2.23656444563837, "Generalised tonic-clonic seizure ": 2.639437953824304, "Genital anaesthesia ": 6.272130450456058, "Genital atrophy ": 7.229322137377884, "Genital hypoaesthesia ": 4.030809328257837, "Genital paraesthesia ": 2.380186294720142, "Gingival discomfort ": 2.3338705466510508, "Gingival erosion ": 2.34264995267084, "Gingival erythema ": 2.1539091030294992, "Gingival hyperpigmentation ": 2.387804269380746, "Gingival hypertrophy ": 2.821325483550392, "Gingival oedema ": 2.557117244310146, "Gitelman's syndrome ": 3.615082672656949, "Glossitis ": 2.2492331093831672, "Glossoptosis ": 4.767900239223762, "Gluten sensitivity ": 2.0451769405011837, "Grandiosity ": 2.1468283283529, "Granulocytopenia ": 3.2201607327241057, "Grey syndrome neonatal ": 2.5907254632306738, "Grief reaction ": 2.2259207123210967, "Gross motor delay ": 5.949776680630173, "Growth accelerated ": 2.216280710420783, "Growth retardation ": 3.9330467254331314, "Gun shot wound ": 3.0802216977826347, "Gynaecomastia ": 3.803797207469064, "HELLP syndrome ": 2.6292082527673264, "Haemangioma congenital ": 3.308970672206197, "Haemarthrosis ": 2.2772461758699483, "Haematological malignancy ": 2.1703606170079426, "Haematoma muscle ": 3.43351140776761, "Haemoconcentration ": 2.650056585819588, "Haemodialysis complication ": 2.720993284414149, "Haemodynamic instability ": 2.167595303249528, "Haemoperitoneum ": 2.4788470182341094, "Haemorrhagic disorder ": 2.04733162588644, "Haemorrhoids ": 2.645297048125697, "Hair growth abnormal ": 2.917848069074385, "Hair texture abnormal ": 2.470081556627413, "Hair transplant ": 10.633026989774171, "Hallucination ": 2.418073440833141, "Hallucination, visual ": 2.67856468673834, "Hallucinations, mixed ": 2.567604466216125, "Harlequin syndrome ": 2.2450342229325893, "Head circumference abnormal ": 2.0301784492250383, "Head deformity ": 3.586585324006094, "Heart block congenital ": 2.6974128087585774, "Heart disease congenital ": 6.039561546973297, "Heart sounds abnormal ": 2.272948378406922, "Helicobacter gastritis ": 2.685437891924619, "Helicobacter test positive ": 2.2107096800193835, "Hemianopia heteronymous ": 2.589912226151715, "Henoch-Schonlein purpura ": 2.2455087807647858, "Heparin-induced thrombocytopenia ": 10.182253128045916, "Heparin-induced thrombocytopenia test ": 9.293779407489364, "Hepatic adenoma ": 2.52244442391094, "Hepatic atrophy ": 2.624735161095654, "Hepatic cancer ": 3.804735377848458, "Hepatic function abnormal ": 2.51863494617491, "Hepatic necrosis ": 2.6082047638926658, "Hepatic vein dilatation ": 2.1384350701399795, "Hepatitis acute ": 2.8892017832673718, "Hepatitis cholestatic ": 4.64496202752805, "Hepatitis fulminant ": 2.746647205373114, "Hepatitis non-A non-B ": 2.2450342229325893, "Hepatitis toxic ": 2.9248328510803927, "Hepato-lenticular degeneration ": 2.936222849208289, "Hepatocellular injury ": 2.9007881682328405, "Herbal interaction ": 3.183863684710422, "Hereditary angioedema ": 9.62923465902985, "Hereditary angioedema with C1 esterase inhibitor deficiency ": 2.4674108568917084, "Hernia congenital ": 2.6473914494403386, "Hernia hiatus repair ": 3.053687468309727, "Heterophoria ": 3.38955926305894, "Heterotopic pregnancy ": 4.198672806064916, "Hiatus hernia ": 3.717612659088181, "Hiccups ": 2.697561980184705, "High arched palate ": 6.536504304697172, "Hirsutism ": 2.208457376984849, "Histology abnormal ": 2.065602363262541, "Histone antibody positive ": 2.9024745245448345, "Holoprosencephaly ": 2.279796500993944, "Homicidal ideation ": 2.303396878402684, "Homicide ": 4.9188043205911285, "Hostility ": 2.5214045148074486, "Human chorionic gonadotropin increased ": 5.981185033238219, "Human herpes virus 6 serology positive ": 2.515908217122853, "Huntington's disease ": 6.067551201987004, "Hydrocele ": 2.357795821263958, "Hydrops foetalis ": 2.5623980667993767, "Hyperaemia ": 2.9507218982906527, "Hyperammonaemia ": 4.879844631007289, "Hyperammonaemic encephalopathy ": 6.520156493951414, "Hypercalciuria ": 2.611264679283238, "Hypercapnic coma ": 3.2440154132938024, "Hyperchloraemia ": 3.617785709438192, "Hyperglobulinaemia ": 6.302341794921743, "Hyperintensity in brain deep nuclei ": 3.9356187523285056, "Hyperkalaemia ": 3.874320612166048, "Hyperkinesia ": 3.485160604075505, "Hyperkinetic heart syndrome ": 3.6147353771008457, "Hyperlactacidaemia ": 2.3397876309059, "Hypermagnesaemia ": 6.187028974283551, "Hypernatraemia ": 2.8485310982203207, "Hyperoxaluria ": 2.441393592880345, "Hyperparathyroidism primary ": 2.955484858645617, "Hyperprolactinaemia ": 2.648386313802924, "Hyperreflexia ": 3.889250719444564, "Hypersensitivity myocarditis ": 2.068190904451604, "Hypersensitivity vasculitis ": 2.502849739652757, "Hypertelorism ": 9.826484057423494, "Hypertension neonatal ": 3.0390232848659395, "Hyperthermia ": 2.148161078465519, "Hyperthermia malignant ": 3.1507725390669017, "Hypertonia ": 3.8665451334302094, "Hypertonia neonatal ": 6.574430879129772, "Hypertrichosis ": 4.681538921448591, "Hypervigilance ": 2.064737156590052, "Hypervitaminosis ": 2.070447818919116, "Hypervitaminosis A ": 2.848173647013041, "Hypervitaminosis D ": 3.018316396517281, "Hypocalvaria ": 5.39741127910699, "Hypocapnia ": 2.196982643309022, "Hypocarnitinaemia ": 8.009118968725161, "Hypochloraemia ": 5.018499096748638, "Hypocholesterolaemia ": 2.6215031579876475, "Hypocitraturia ": 4.802594096429057, "Hypocoagulable state ": 14.64569272558812, "Hypogonadism ": 3.9486427027687303, "Hypogonadism male ": 2.9839020141957677, "Hypohidrosis ": 4.17329705998042, "Hypokalaemia ": 5.568785019220675, "Hypokinesia neonatal ": 5.198964971256344, "Hyponatraemia ": 4.209493603969707, "Hyponatraemic encephalopathy ": 8.061190422622072, "Hyponatraemic seizure ": 5.10847007168488, "Hyponatraemic syndrome ": 4.140350862180093, "Hypoosmolar state ": 2.83139323334466, "Hypoperfusion ": 2.417515590433675, "Hypoplastic anaemia ": 4.141223174152671, "Hypoplastic left heart syndrome ": 9.65798831717102, "Hypoplastic right heart syndrome ": 5.731706343934361, "Hypoprothrombinaemia ": 14.45160416332334, "Hyporeflexia ": 2.222396374569204, "Hypospadias ": 7.868995535344396, "Hyposthenuria ": 3.07919380766695, "Hypotelorism of orbit ": 6.78597621727484, "Hypotension ": 2.5994171717639523, "Hypotensive transfusion reaction ": 6.272130450456058, "Hypothalamic pituitary adrenal axis suppression ": 3.086561168593964, "Hypothermia ": 2.33410298962818, "Hypothermia neonatal ": 2.4815607600334006, "Hypothrombinaemia ": 2.762913163152542, "Hypotonia neonatal ": 7.266012887858744, "Hypotony of eye ": 2.203448711752774, "Hypotrichosis ": 2.0301784492250383, "Hypoventilation ": 2.085488309373476, "Hypoventilation neonatal ": 2.154150020697041, "Hypovolaemia ": 2.023729014112016, "Hypoxic-ischaemic encephalopathy ": 2.135755002766772, "Hypozincaemia ": 7.408067933199498, "Hysteroscopy ": 5.172121072992665, "Iatrogenic injury ": 2.59678681761694, "Ideas of reference ": 2.7893707053248438, "Idiopathic intracranial hypertension ": 2.704367944583116, "Idiosyncratic drug reaction ": 3.752291490910505, "Ileus paralytic ": 2.8170180141291388, "Illiteracy ": 2.140171203093644, "Impaired driving ability ": 2.0811565734846176, "Impaired reasoning ": 2.662923799026622, "Impatience ": 2.1065616452886915, "Implant site haematoma ": 2.531466042797645, "Implant site reaction ": 4.705583054188087, "Implantation complication ": 5.338774251570324, "Impulsive behaviour ": 3.0792959174125096, "Inability to afford medication ": 2.596063513114127, "Inadequate analgesia ": 4.13524740584665, "Inadequate lubrication ": 3.487298748185552, "Inappropriate affect ": 2.5877278709604017, "Inappropriate antidiuretic hormone secretion ": 4.042461779876607, "Incision site haematoma ": 2.8865086325763807, "Incoherent ": 2.128198867886594, "Incorrect dosage administered ": 2.5920021777620508, "Incorrect dose administered by product ": 2.923384706208534, "Incorrect drug administration rate ": 3.412071858392461, "Incorrect product administration duration ": 3.729277548026035, "Incorrect product dosage form administered ": 3.177754976232754, "Incorrect product formulation administered ": 2.127358162107789, "Indifference ": 2.8392493690905973, "Induced abortion failed ": 298.2484284628898, "Induced abortion haemorrhage ": 3.442779540174401, "Infantile apnoea ": 3.448681650578457, "Infantile spasms ": 2.8970580602378413, "Infection via vaccinee ": 2.154150020697041, "Infertility male ": 5.063403774760271, "Infusion site extravasation ": 2.7848923619466923, "Infusion site granuloma ": 4.689831001001493, "Infusion site inflammation ": 2.7021461556511475, "Infusion site necrosis ": 2.4699264535838386, "Infusion site oedema ": 3.111937376872949, "Infusion site phlebitis ": 6.692700128478317, "Inhalation therapy ": 19.0111691735073, "Inhibitory drug interaction ": 2.2362220639573427, "Injection site granuloma ": 4.831281054603175, "Injection site hypertrichosis ": 3.442779540174401, "Injection site ischaemia ": 7.136878144484689, "Injection site joint inflammation ": 2.7801871827442293, "Injection site laceration ": 4.773427223895921, "Injection site necrosis ": 2.140831190131402, "Injection site pallor ": 4.995997872223249, "Injection site phlebitis ": 12.442638870519998, "Injection site thrombosis ": 5.54755357753633, "Instillation site erythema ": 4.9551076627161, "Instillation site foreign body sensation ": 3.5148518229747605, "Instillation site irritation ": 4.469397015128806, "Instillation site pruritus ": 2.119843710264686, "Insulin-like growth factor decreased ": 4.920891343497318, "Insulin-like growth factor increased ": 4.910833575490411, "Intellectual disability ": 5.877015326170559, "Intelligence test abnormal ": 4.593336151050352, "Intention tremor ": 2.2968835216399444, "Intentional device misuse ": 5.910703605176792, "Intentional device use issue ": 2.1447791014765603, "Intentional misuse of drug delivery system ": 9.167961729456698, "Intentional overdose ": 6.257861830906898, "Intentional product misuse ": 3.517618132289173, "Intentional product misuse to child ": 2.4699264535838386, "Intentional removal of drug delivery system by patient ": 4.388694975075853, "Intentional self-injury ": 6.770219572095157, "Intercepted product prescribing error ": 2.2517713372367423, "Intermittent explosive disorder ": 2.589912226151715, "Internal hernia ": 2.0381992078055684, "Internal injury ": 2.154232826945312, "International normalised ratio ": 3.71029999959756, "International normalised ratio abnormal ": 4.05104163212557, "International normalised ratio decreased ": 4.29020541406559, "International normalised ratio fluctuation ": 6.017369906330414, "International normalised ratio increased ": 7.635049036833043, "Interruption of aortic arch ": 2.738922347820625, "Intestinal angioedema ": 20.70010675939629, "Intestinal atony ": 2.184478674164116, "Intestinal diaphragm disease ": 10.368582664778728, "Intestinal haematoma ": 4.8844696433317205, "Intestinal intraepithelial lymphocytes increased ": 5.030340738416564, "Intestinal metaplasia ": 2.4268961105938494, "Intestinal mucosal atrophy ": 3.77657001277882, "Intestinal pseudo-obstruction ": 2.7898954726195164, "Intestinal strangulation ": 2.141940521401468, "Intestinal villi atrophy ": 7.674203765957176, "Intra-abdominal haematoma ": 3.878139371022612, "Intra-abdominal haemorrhage ": 2.249400365974449, "Intraventricular haemorrhage neonatal ": 4.637751870891568, "Intrusive thoughts ": 2.35103832431833, "Invasive ductal breast carcinoma ": 4.165501834746796, "Invasive lobular breast carcinoma ": 3.2138035809535523, "Iodine uptake decreased ": 3.457645315486185, "Iridotomy ": 2.158702033383775, "Iris atrophy ": 2.163947849098682, "Iris disorder ": 2.490319740474784, "Iris hypopigmentation ": 13.164543590896496, "Iris transillumination defect ": 32.63103118347658, "Ischaemic gastritis ": 3.5148518229747605, "Jarisch-Herxheimer reaction ": 5.731858389088097, "Jaundice ": 2.3162581232411776, "Jaundice cholestatic ": 2.55630729006296, "Joint hyperextension ": 2.330669416153329, "Judgement impaired ": 3.4935845418473277, "Keratomileusis ": 3.018048574023795, "Kernicterus ": 2.5907254632306738, "Kidney malformation ": 3.684371222587131, "Knee deformity ": 3.025392311614878, "Kounis syndrome ": 3.9023465109457542, "Labelled drug-disease interaction medication error ": 5.231059677944292, "Labelled drug-food interaction issue ": 4.000509736211133, "Labelled drug-food interaction medication error ": 2.005000870635928, "Laboratory test interference ": 2.7501301876753126, "Labour augmentation ": 5.198964971256344, "Labour complication ": 2.2990917653458, "Lacrimation decreased ": 2.0063382529418163, "Lacrimation disorder ": 2.413910384021141, "Lactate pyruvate ratio increased ": 2.119843710264686, "Lactic acidosis ": 4.654093293193839, "Large intestine polyp ": 4.937059921241006, "Laryngeal discomfort ": 2.650206510753934, "Laryngeal dyspnoea ": 4.587349568439264, "Laryngeal haematoma ": 2.356026082357269, "Laryngeal oedema ": 4.274417860326705, "Laryngeal pain ": 2.249578507082471, "Laryngomalacia ": 2.581452788607616, "Laryngospasm ": 4.358067288577303, "Laryngotracheal oedema ": 9.458141235220344, "Laryngotracheal operation ": 5.198964971256344, "Larynx irritation ": 2.023886935467474, "Learning disability ": 4.463229935315746, "Learning disorder ": 10.048640591924991, "Left ventricle outflow tract obstruction ": 3.859667713920546, "Leucine aminopeptidase increased ": 12.220140829168235, "Leuconostoc infection ": 2.6556073102073143, "Leukaemoid reaction ": 2.287399874957282, "Leukocyte alkaline phosphatase increased ": 4.300975156186353, "Leukocytosis ": 2.1871848229354702, "Leukonychia ": 2.224121452268076, "Libido decreased ": 4.8946350951620925, "Libido disorder ": 2.2930071897638866, "Life expectancy shortened ": 12.865521889241586, "Life support ": 3.3226791819194994, "Ligament laxity ": 3.552772685977802, "Limb asymmetry ": 2.8422024405568638, "Limb hypoplasia congenital ": 6.639262375097111, "Limb reduction defect ": 4.373749325542392, "Linear IgA disease ": 7.122006539340007, "Lip disorder ": 2.201223209577031, "Lip erosion ": 2.5478623390386144, "Lip erythema ": 2.4876892533848878, "Lip exfoliation ": 2.001389135307804, "Lip oedema ": 4.97136957254804, "Lip swelling ": 2.079295260197871, "Lipogranuloma ": 2.6556073102073143, "Lissencephaly ": 2.739337169947462, "Liver palpable ": 3.215202769711489, "Local anaesthetic systemic toxicity ": 3.0624739922083037, "Loeffler's syndrome ": 3.792326896754684, "Logorrhoea ": 3.702026827524416, "Long QT syndrome ": 3.975022039769379, "Long QT syndrome congenital ": 4.155425732610098, "Loose associations ": 2.5322569562112758, "Lordosis ": 2.537397259285423, "Loss of employment ": 4.636509986348207, "Loss of libido ": 5.44038396549083, "Low density lipoprotein decreased ": 3.778876509953263, "Low set ears ": 3.094654202318216, "Lung carcinoma cell type unspecified stage I ": 3.438562821726312, "Lung carcinoma cell type unspecified stage III ": 2.045240671351275, "Lung neoplasm malignant ": 2.650877455908001, "Lung operation ": 2.434975583340463, "Lymphocyte morphology abnormal ": 2.552822903877229, "Lymphocyte stimulation test ": 3.0938723142390154, "Lymphocyte stimulation test positive ": 5.669039459795369, "Macrocephaly ": 2.566265663764024, "Macroglossia ": 2.715043369295507, "Malabsorption ": 6.96587064876283, "Malabsorption from application site ": 4.300975156186353, "Malaria ": 2.0212289754145263, "Male genital atrophy ": 4.934436336095037, "Male orgasmic disorder ": 6.265623095496101, "Male reproductive tract disorder ": 3.223244446764583, "Male sexual dysfunction ": 3.7249674127896375, "Malocclusion ": 3.709147026364101, "Mammogram abnormal ": 3.880291025884471, "Mania ": 3.5628549587428404, "Manufacturing issue ": 4.087854129026545, "Manufacturing materials issue ": 2.8181737538583063, "Marfan's syndrome ": 4.680092339331298, "Marital problem ": 3.75078864372996, "Mastectomy ": 2.040054694944704, "Maternal drugs affecting foetus ": 5.452461991893415, "Maternal exposure during delivery ": 7.157070214281162, "Mean arterial pressure decreased ": 2.102911391962367, "Measles ": 6.399006905116629, "Measles antibody negative ": 2.790604720356131, "Measles post vaccine ": 5.085845879805, "Meconium abnormal ": 4.469397015128806, "Meconium in amniotic fluid ": 4.022890261345194, "Medication crystals in urine present ": 3.615082672656949, "Medication error ": 3.132963184388722, "Medication overuse headache ": 2.142964164603532, "Medulloblastoma ": 2.151954624278827, "Megacolon ": 2.325530409594286, "Melanosis ": 3.4178729931212524, "Meningioma ": 3.155245049152494, "Meningitis chemical ": 2.216989853625224, "Meningocele ": 3.226473374678685, "Meningomyelocele ": 4.76877766187732, "Mental disability ": 3.21688923472569, "Merycism ": 3.826423134070761, "Mesenteric haematoma ": 2.526902834298863, "Metabolic acidosis ": 2.862740252099892, "Metabolic alkalosis ": 5.491948514937654, "Metabolic encephalopathy ": 2.19872340019254, "Metal poisoning ": 2.3190259513510965, "Metanephrine urine increased ": 4.007036161400551, "Microcephaly ": 4.565595627530554, "Microgenia ": 2.0925266228089137, "Micrognathia ": 4.939258664128763, "Micropenis ": 2.182707492679382, "Microphthalmos ": 2.916728444196855, "Microvillous inclusion disease ": 3.6147353771008457, "Micturition disorder ": 2.3821266380902024, "Milk-alkali syndrome ": 3.358155988248352, "Mini mental status examination abnormal ": 2.5322569562112758, "Miosis ": 5.611761010374255, "Mitochondrial encephalomyopathy ": 2.0384881070613017, "Mitochondrial enzyme deficiency ": 2.848173647013041, "Mitral valve atresia ": 2.040534036553507, "Mitral valve sclerosis ": 2.219522144485229, "Mitral valve stenosis ": 2.1203067530260964, "Mixed liver injury ": 2.575762878304656, "Modified radical mastectomy ": 9.527343403928812, "Morbid thoughts ": 2.234088760968957, "Morbillivirus test positive ": 4.1423793880704975, "Morose ": 2.863469777983985, "Motor developmental delay ": 3.263020816914346, "Mouth swelling ": 3.4809418720626737, "Mucosa vesicle ": 2.7309725355112, "Mucosal erosion ": 3.1369432874498626, "Mucosal exfoliation ": 3.012772679945205, "Mucosal hyperaemia ": 2.6146608751144047, "Mucosal membrane hyperplasia ": 4.010584589699205, "Multiple cardiac defects ": 2.1384046678205544, "Multiple congenital abnormalities ": 9.817096270568506, "Multiple pregnancy ": 2.067710689608565, "Mumps ": 10.488353438609238, "Mumps antibody test negative ": 2.6282276649410377, "Muscle haemorrhage ": 2.192760636749671, "Muscle necrosis ": 3.1569513411924524, "Muscle rigidity ": 2.3687563847998536, "Muscle rupture ": 2.275859276764477, "Muscle tone disorder ": 2.154033910838173, "Musculoskeletal injury ": 7.603510004502053, "Mycobacterium ulcerans infection ": 18.312818235900263, "Mydriasis ": 5.07843861761456, "Myocardial depression ": 3.796835854988803, "Myocardial haemorrhage ": 2.0495228807388, "Myocardial stunning ": 10.792995139835782, "Myoclonus ": 3.4533882796224136, "Myofascitis ": 2.7354562412626264, "Myoglobin blood increased ": 2.600188106237404, "Myoglobin urine ": 2.3165222645963905, "Myoglobin urine present ": 2.976063820706978, "Myoglobinaemia ": 4.07007745522992, "Myoglobinuria ": 4.554983330015176, "Myopathy ": 3.3644495651859514, "Myopia ": 4.2726863339301975, "Narcissistic personality disorder ": 2.321372237564148, "Narrow anterior chamber angle ": 3.0265595087464576, "Nasal cavity cancer ": 6.810075230560672, "Nasal discomfort ": 2.231900859233242, "Nasal disorder ": 2.7592624802170604, "Nasal mucosal disorder ": 2.384665230385425, "Nasal pruritus ": 3.157489095767474, "Nasal septum perforation ": 3.349460294629244, "Nasal septum ulceration ": 7.977247753518294, "Nasopharyngeal cancer ": 2.703349121596609, "Near death experience ": 2.149740922028582, "Necrolytic migratory erythema ": 2.387804269380746, "Necrosis ischaemic ": 2.1840310555248794, "Necrotising colitis ": 3.608846172111333, "Needle issue ": 2.0235578051964285, "Needle track marks ": 4.893428407223816, "Negativism ": 2.0412460480762418, "Neonatal anoxia ": 2.1706108345009483, "Neonatal anuria ": 2.856126191322969, "Neonatal asphyxia ": 4.093710481331146, "Neonatal behavioural syndrome ": 3.1287473158599246, "Neonatal cholestasis ": 3.87893833691815, "Neonatal disorder ": 2.6325165099319694, "Neonatal hypotension ": 3.0041773045320355, "Neonatal hypoxia ": 3.6264816480187143, "Neonatal infection ": 3.3399747004831646, "Neonatal pneumothorax ": 3.018048574023795, "Neonatal respiratory arrest ": 2.4593523396094774, "Neonatal respiratory depression ": 3.631418343302053, "Neonatal respiratory distress ": 3.0466004827729294, "Neonatal respiratory distress syndrome ": 2.4411862062532084, "Neonatal respiratory failure ": 3.9826354958906576, "Neonatal seizure ": 4.794057847239342, "Neonatal tachycardia ": 2.489100169809212, "Neonatal tachypnoea ": 2.239033257618621, "Neonatal toxicity ": 5.5955177896771575, "Neoplasm malignant ": 2.5758538298588416, "Nephritis allergic ": 2.643496268847826, "Nephrocalcinosis ": 2.5658516979654964, "Nephrogenic diabetes insipidus ": 5.802790186340983, "Nephrogenic systemic fibrosis ": 2.309298947705535, "Nervousness ": 2.526693448266528, "Neural tube defect ": 9.12527190069441, "Neurectomy ": 2.8888362465479496, "Neurodevelopmental disorder ": 11.904228559389969, "Neuroleptic malignant syndrome ": 2.770869038728204, "Neuromuscular block prolonged ": 4.390618781840559, "Neuromuscular blockade ": 3.4457302777719123, "Neuromuscular blocking therapy ": 15.590822419093616, "Neuromyopathy ": 2.280959455756404, "Neuropsychological symptoms ": 6.357208008222257, "Neurotransmitter level altered ": 2.2215263940755143, "Neutralising antibodies positive ": 2.838782617585562, "Newborn persistent pulmonary hypertension ": 24.94847964235029, "Nicotine dependence ": 26.203675378634653, "Nicotinic acid deficiency ": 3.339546348012921, "Nightmare ": 2.33037598534243, "Nikolsky's sign ": 2.154046336827644, "Nipple disorder ": 3.051364619219909, "Nocturnal fear ": 2.7083890562614026, "Nodal arrhythmia ": 8.735195699572643, "Nodal rhythm ": 7.916898692157472, "Non-cardiogenic pulmonary oedema ": 2.5800671895893976, "Non-immune heparin associated thrombocytopenia ": 3.1877485848580447, "Noninfectious peritonitis ": 4.793129411962667, "Nonspecific reaction ": 2.303106799524413, "Nontherapeutic agent urine positive ": 3.5424778899304763, "Noonan syndrome ": 3.178702039398656, "Normetanephrine urine increased ": 3.487298748185552, "Nose deformity ": 6.451996972234148, "Nosophobia ": 4.300975156186353, "Nystagmus ": 2.839953917591586, "Obsessive thoughts ": 2.237770939281953, "Occupational asthma ": 2.2796882444559303, "Oculoauriculovertebral dysplasia ": 2.762913163152542, "Oculogyric crisis ": 3.363162173696292, "Oculomucocutaneous syndrome ": 4.644398536330027, "Oedema genital ": 2.323994115839095, "Oedema mouth ": 19.54644672009796, "Oedema mucosal ": 2.8637850970169896, "Oedema neonatal ": 2.5907254632306738, "Oesophageal carcinoma ": 15.796353934681983, "Oesophageal discomfort ": 2.838728414981406, "Oesophageal injury ": 2.83139323334466, "Oesophageal irritation ": 3.995992352689222, "Oesophageal obstruction ": 2.045398491126318, "Oesophageal oedema ": 2.0976434733784406, "Oesophageal pain ": 3.5285841559870312, "Oesophagitis chemical ": 4.172004983808182, "Oestradiol increased ": 4.375679922124095, "Oestrogen deficiency ": 2.748830212428649, "Oestrogen receptor assay positive ": 4.831632651095809, "Off label use of device ": 5.87698667678919, "Oligohydramnios ": 4.319353368958843, "Oligospermia ": 6.421723954633703, "Oliguria ": 3.030528413522446, "Onychophagia ": 2.999112472942262, "Opiates positive ": 2.387538094559576, "Opisthotonus ": 5.5302567009443, "Oppositional defiant disorder ": 3.555003800928013, "Optic nerve hypoplasia ": 5.172121072992665, "Oral administration complication ": 2.767046335723498, "Oral allergy syndrome ": 6.946393816732602, "Oral discharge ": 2.531466042797645, "Oral discomfort ": 3.334646751470425, "Oral mucosa erosion ": 3.0101624491095134, "Oral mucosal discolouration ": 2.860039857558307, "Oral mucosal eruption ": 2.829994390230411, "Oral mucosal erythema ": 3.286674079163142, "Oral mucosal exfoliation ": 2.6578987005891603, "Oral mucosal roughening ": 2.208597383915884, "Oral papule ": 4.910307140806525, "Oral pruritus ": 6.922923128016432, "Orbital haemorrhage ": 2.567861733067455, "Orbital oedema ": 2.7476276713017143, "Orchitis mumps ": 4.406448101978552, "Organic erectile dysfunction ": 3.661767206368689, "Orgasm abnormal ": 4.273314163819546, "Orgasmic sensation decreased ": 6.024203529332313, "Oromandibular dystonia ": 2.2883546138442954, "Oropharyngeal scar ": 3.615082672656949, "Oropharyngeal swelling ": 2.781564216239956, "Oropharyngitis fungal ": 2.516331049844454, "Orthosis user ": 4.497846157096005, "Orthostatic hypotension ": 2.635128342332101, "Osmolar gap abnormal ": 4.843626274582155, "Osmotic demyelination syndrome ": 3.1376920967560387, "Osteochondritis ": 2.441393592880345, "Otitis media chronic ": 2.017758176683172, "Otospondylomegaepiphyseal dysplasia ": 4.79129469592632, "Ototoxicity ": 2.523492912438566, "Ovarian cancer ": 3.063226128238768, "Ovarian cancer metastatic ": 2.2687650005360758, "Ovarian rupture ": 3.540905648144215, "Overdose ": 4.267992161622221, "Oxalosis ": 2.182707492679382, "Oxygen consumption ": 2.9024745245448345, "Oxygen therapy ": 2.335389151187984, "PCO2 decreased ": 2.8697248265443647, "PO2 decreased ": 2.314794342296027, "Packaging design issue ": 2.5460556445726743, "Paget's disease of nipple ": 2.2450342229325893, "Painful ejaculation ": 3.576373745791844, "Palatal oedema ": 4.290335942789303, "Palmar erythema ": 2.001855876464097, "Panic disorder ": 2.417258715672065, "Panic reaction ": 2.5282716852007785, "Pantoea agglomerans infection ": 7.99712037139817, "Papule ": 2.854510586496244, "Paradoxical pressor response ": 2.387804269380746, "Paraesthesia mucosal ": 3.0600123374239803, "Paranasal sinus injury ": 2.119843710264686, "Parathyroid gland enlargement ": 2.043655518311099, "Paravenous drug administration ": 7.510767283920724, "Parenteral nutrition associated liver disease ": 5.203844953381612, "Parkinsonian gait ": 2.2705447323482426, "Parkinsonism ": 3.218917769417358, "Parotid gland enlargement ": 2.4518449042620136, "Paroxysmal sympathetic hyperactivity ": 2.844207717923794, "Partner stress ": 3.9906472906582495, "Pasteurella infection ": 2.6974128087585774, "Patent ductus arteriosus ": 7.291347057694717, "Paternal drugs affecting foetus ": 4.826380696809855, "Patient dissatisfaction with treatment ": 2.517955561887787, "Patient elopement ": 2.155481718464486, "Patient restraint ": 2.5907254632306738, "Patient uncooperative ": 3.225583063227329, "Patient-device incompatibility ": 2.145723911501263, "Peak expiratory flow rate decreased ": 2.50781131721724, "Peak expiratory flow rate increased ": 2.848173647013041, "Pectus carinatum ": 5.992219891988702, "Pectus excavatum ": 9.99190506862145, "Pelvic haematoma ": 2.72800811588569, "Penile blister ": 2.4684870470463327, "Penile contusion ": 4.55779258879207, "Penile curvature ": 2.0617677569376225, "Penile haematoma ": 5.8435418733158135, "Penile necrosis ": 3.206012394354377, "Penile oedema ": 2.143384173871464, "Penile operation ": 2.5907254632306738, "Penile size reduced ": 10.013420854280112, "Penis disorder ": 2.064668594260769, "Penis injury ": 2.721448279980755, "Peptic ulcer ": 2.5372584319444886, "Peptic ulcer perforation ": 2.065602363262541, "Performance enhancing product use ": 2.59950973928883, "Pericarditis adhesive ": 2.992703786062721, "Periorbital irritation ": 2.158702033383775, "Periorbital oedema ": 2.712119060780732, "Peripartum cardiomyopathy ": 2.279485601685458, "Peripartum haemorrhage ": 3.0938723142390154, "Periportal sinus dilatation ": 2.7324561440655404, "Peritoneal cloudy effluent ": 23.340019202682, "Peritoneal dialysis complication ": 23.00939142604211, "Peritoneal effluent abnormal ": 7.580088704520082, "Periventricular leukomalacia ": 3.0632229490426384, "Persistent foetal circulation ": 3.9844657603791687, "Persistent generalised lymphadenopathy ": 2.8246314187502346, "Persistent left superior vena cava ": 4.680092339331298, "Personal relationship issue ": 3.4167243693843647, "Personality change ": 2.236225875340597, "Personality disorder ": 2.142239847496612, "Perthes disease ": 4.772904135896998, "Petit mal epilepsy ": 2.104007524086255, "Peyronie's disease ": 2.427217477504736, "Phaeochromocytoma ": 2.159711925015488, "Phalangeal hypoplasia ": 4.02283837449332, "Pharmaceutical nomadism ": 10.510138366415156, "Pharyngeal erythema ": 2.1324966264655565, "Pharyngeal haematoma ": 2.1589937134569936, "Pharyngeal injury ": 4.809482967964405, "Pharyngeal oedema ": 3.9569876829917208, "Pharyngeal operation ": 2.1497644818720323, "Phobia ": 2.4200536385003977, "Physical abuse ": 4.826380696809855, "Physical assault ": 2.553016376091892, "Physical disability ": 9.086383900683314, "Physical product label issue ": 2.1997009292346097, "Pica ": 3.1554650401827407, "Pickwickian syndrome ": 2.216280710420783, "Pigment dispersion syndrome ": 9.575409445861082, "Pigment nephropathy ": 2.6556073102073143, "Pigmentation disorder ": 2.123934774645688, "Pituitary apoplexy ": 3.5103262795406023, "Pituitary tumour ": 3.065592630020129, "Pituitary tumour benign ": 2.191161186509677, "Pituitary tumour recurrent ": 3.3500130170480302, "Pituitary tumour removal ": 8.825496783869223, "Plagiocephaly ": 5.973252903537125, "Plasmodium falciparum infection ": 2.321372237564148, "Plasmodium vivax infection ": 2.158702033383775, "Platelet adhesiveness decreased ": 2.119843710264686, "Pneumocephalus ": 3.7069770407614007, "Pneumoconiosis ": 3.913732912441447, "Pneumonitis aspiration ": 2.13732309411946, "Poisoning ": 4.60836816992855, "Poisoning deliberate ": 9.288618320469602, "Poland's syndrome ": 3.1548067533935624, "Polydactyly ": 3.05879853322794, "Polyhydramnios ": 2.6693936137508825, "Polyp ": 2.1031473174941286, "Poor feeding infant ": 2.351622414669142, "Poor personal hygiene ": 2.33315261325578, "Poor quality device used ": 34.589314240903875, "Poor quality product administered ": 3.2184540264612056, "Poor sucking reflex ": 3.654332297223388, "Porencephaly ": 2.039414910660589, "Poriomania ": 5.068942649117353, "Porphyria ": 2.060349732016189, "Post 5-alpha-reductase inhibitor syndrome ": 17.481807052488172, "Post embolisation syndrome ": 4.038627971753013, "Post-tussive vomiting ": 2.0464318866351654, "Postictal state ": 2.320858418961638, "Postmortem blood drug level abnormal ": 15.211422364983385, "Postmortem blood drug level increased ": 5.961318397796992, "Postnatal growth restriction ": 4.1423793880704975, "Postpartum haemorrhage ": 2.950196851229682, "Postpartum stress disorder ": 6.78597621727484, "Postural tremor ": 2.0209537743770083, "Posturing ": 2.208597383915884, "Potentiating drug interaction ": 2.746046374425543, "Potter's syndrome ": 5.148543192577682, "Poverty ": 8.009118968725161, "Poverty of speech ": 2.1142542249800265, "Precipitate labour ": 11.863951839656613, "Precocious puberty ": 2.692894283708174, "Pregnancy on oral contraceptive ": 22.529648166669475, "Premature ejaculation ": 3.8687120197152, "Premature recovery from anaesthesia ": 5.907197081000589, "Premature separation of placenta ": 2.630739988370026, "Presbyoesophagus ": 3.615082672656949, "Prescription drug used without a prescription ": 2.799558603875971, "Prescription form tampering ": 9.934545626438448, "Pressure of speech ": 2.9538777157993703, "Procedural hypotension ": 2.456730492580001, "Procedural shock ": 2.8246314187502346, "Product adhesion issue ": 11.538176703883272, "Product administration error ": 3.675016194065194, "Product after taste ": 3.88628898007962, "Product appearance confusion ": 3.2285115701860283, "Product availability issue ": 2.98729263941848, "Product blister packaging issue ": 3.046219421583188, "Product caught fire ": 5.897460791394173, "Product cleaning inadequate ": 28.410666566280582, "Product closure issue ": 3.457645315486185, "Product closure removal difficult ": 7.229322137377884, "Product coating issue ": 6.115388537611228, "Product colour issue ": 4.223533455697868, "Product commingling ": 4.655308371133672, "Product complaint ": 5.608788608018839, "Product compounding quality issue ": 4.292195308414041, "Product confusion ": 2.840853036468754, "Product container issue ": 2.215441943306689, "Product container seal issue ": 2.611291489515862, "Product contamination ": 3.4049457148235858, "Product contamination chemical ": 20.440090127758925, "Product contamination microbial ": 4.092058684049487, "Product contamination physical ": 2.362693008173615, "Product counterfeit ": 2.142719995295475, "Product delivery mechanism issue ": 9.265826238224996, "Product deposit ": 5.278284416263158, "Product design confusion ": 3.0938723142390154, "Product design issue ": 3.345147135380988, "Product dispensing error ": 3.193394836967029, "Product dispensing issue ": 2.52699458851551, "Product dosage form confusion ": 3.0915894918603004, "Product dosage form issue ": 5.551760277563229, "Product formulation issue ": 11.653632592534928, "Product impurity ": 3.906261862577389, "Product intolerance ": 2.40622094449741, "Product label confusion ": 2.2974437054956462, "Product label issue ": 2.906603184764656, "Product label on wrong product ": 6.541596807880673, "Product lot number issue ": 2.19641142827624, "Product measured potency issue ": 3.8676647592770874, "Product monitoring error ": 2.2660193473742134, "Product name confusion ": 5.092955636029015, "Product odour abnormal ": 9.43895845494856, "Product origin unknown ": 3.582119543491137, "Product outer packaging issue ": 2.3785921265590324, "Product package associated injury ": 10.502921019704605, "Product packaging confusion ": 9.487583063695, "Product packaging difficult to open ": 3.041990472461201, "Product packaging issue ": 4.237851257421613, "Product packaging quantity issue ": 2.9803549550841804, "Product physical consistency issue ": 8.677353264109586, "Product physical issue ": 2.4561054683055548, "Product preparation error ": 2.1414856755277847, "Product prescribing error ": 2.831118956680083, "Product prescribing issue ": 2.756272689832585, "Product primary packaging issue ": 8.713709740761487, "Product quality issue ": 3.5561781652399813, "Product reconstitution quality issue ": 3.20618593011718, "Product residue present ": 5.7351314234840665, "Product selection error ": 3.7263833547840566, "Product shape issue ": 4.416696116520047, "Product solubility abnormal ": 9.327814922420602, "Product substitution ": 2.807860034721575, "Product substitution issue ": 11.234851344764856, "Product supply issue ": 3.919727222365293, "Product tampering ": 3.936064980832032, "Product taste abnormal ": 14.107072374285798, "Product use complaint ": 3.784861482209704, "Product use in unapproved indication ": 2.0168569315924803, "Product with quality issue administered ": 13.829769084571922, "Progesterone decreased ": 2.242505380349595, "Progesterone increased ": 4.194235525893107, "Progesterone receptor assay positive ": 3.79363972685902, "Prognathism ": 4.636634725002985, "Prolactin-producing pituitary tumour ": 4.979405671064821, "Prolonged rupture of membranes ": 2.2796882444559303, "Prominent epicanthal folds ": 9.9526502563786, "Propofol infusion syndrome ": 12.986844603768988, "Propulsive gait ": 4.143453142560489, "Prostate cancer ": 3.162337002861423, "Prostate cancer stage I ": 2.9407983789400665, "Prostate cancer stage II ": 7.229322137377884, "Prostate cancer stage III ": 6.406470326786169, "Prostatectomy ": 2.3324848978728823, "Prostatic disorder ": 2.125424387986033, "Prostatic pain ": 2.5669362932198845, "Prostatism ": 2.041280120024456, "Prosthetic cardiac valve thrombosis ": 2.8262385602565785, "Protein C deficiency ": 2.7801871827442293, "Prothrombin level decreased ": 7.052734413838827, "Prothrombin level increased ": 3.765026251591907, "Prothrombin time abnormal ": 2.180809650515524, "Prothrombin time prolonged ": 4.14709740468815, "Prothrombin time ratio decreased ": 4.115152999235356, "Prothrombin time shortened ": 3.095984129282946, "Protrusion tongue ": 2.624762531110566, "Pseudo-Bartter syndrome ": 6.149057498512275, "Pseudocholinesterase deficiency ": 2.567861733067455, "Pseudohypoparathyroidism ": 3.615082672656949, "Pseudolymphoma ": 2.4473951292315634, "Pseudomembranous colitis ": 7.123662467324542, "Pseudomyopia ": 2.6961666124093897, "Pseudophaeochromocytoma ": 2.47292729852726, "Pseudoxanthoma elasticum ": 3.615082672656949, "Psychomotor hyperactivity ": 3.3263442136579977, "Psychomotor retardation ": 3.975188774102112, "Psychomotor skills impaired ": 3.3285856712335136, "Psychosexual disorder ": 3.500420499157024, "Pulmonary artery atresia ": 2.3332252611448574, "Pulmonary artery stenosis ": 3.4845383477500658, "Pulmonary artery stenosis congenital ": 12.782248127989488, "Pulmonary eosinophilia ": 2.4158785589986813, "Pulmonary haemorrhage neonatal ": 4.047972505381089, "Pulmonary hypoplasia ": 3.362580272432991, "Pulmonary interstitial emphysema syndrome ": 3.891465979519322, "Pulmonary malformation ": 4.064830965845844, "Pulmonary microemboli ": 2.807860034721575, "Pulmonary oil microembolism ": 34.32186596818659, "Pulmonary renal syndrome ": 4.035193906684829, "Pulmonary valve incompetence ": 2.0751911590576877, "Pulmonary valve stenosis ": 7.223069845857267, "Pulmonary valve stenosis congenital ": 13.446099804105032, "Pulse absent ": 3.2276635671726743, "Punctate keratitis ": 2.2636491077386136, "Pupil fixed ": 3.06080787153008, "Pupillary block ": 5.194688139804288, "Pupillary light reflex tests abnormal ": 3.010743156584658, "Pupillary reflex impaired ": 3.763455498770373, "Pure white cell aplasia ": 3.780429654414673, "Purple glove syndrome ": 9.072198172684706, "Purpura ": 2.433881446032224, "Pyloric stenosis ": 3.847134167320116, "Pyroglutamate increased ": 2.7324561440655404, "Pyromania ": 5.089377705412014, "QRS axis abnormal ": 2.2755002640684667, "Quadriplegia ": 2.063711060751693, "Radical mastectomy ": 2.617674630797271, "Radical prostatectomy ": 3.8062365289207896, "Radioallergosorbent test positive ": 2.119843710264686, "Rapid eye movement sleep behaviour disorder ": 2.882650336471254, "Rash maculo-papular ": 3.311379679480457, "Rash morbilliform ": 2.308287413422828, "Rash neonatal ": 3.283619010401326, "Rash papular ": 2.051002070621586, "Rash pustular ": 2.102040844081527, "Rash scarlatiniform ": 3.501729012920074, "Reaction to azo-dyes ": 3.487298748185552, "Reaction to colouring ": 3.0694156261115317, "Reaction to excipient ": 2.8184379441578296, "Reaction to sweetener ": 2.6556073102073143, "Reactive gastropathy ": 4.5426632883971685, "Reactive psychosis ": 2.739337169947462, "Reading disorder ": 2.3828843557912904, "Rebound effect ": 2.296025912237014, "Rebound nasal congestion ": 3.859879244102083, "Recalled product ": 57.33777439419582, "Recalled product administered ": 8.231041966961813, "Rectal injury ": 3.162892144732844, "Rectal polyp ": 5.378562024220134, "Regurgitation ": 2.177306174766448, "Rehabilitation therapy ": 2.01101300084213, "Renal aplasia ": 3.570964579397779, "Renal cancer ": 6.929993338556101, "Renal cancer stage I ": 2.041280120024456, "Renal cortical necrosis ": 2.0863895033321707, "Renal dysplasia ": 2.9833298514770688, "Renal failure neonatal ": 3.4946834248401237, "Renal hypoplasia ": 2.3287349339975547, "Renal impairment neonatal ": 3.500561233185535, "Renal vessel congenital anomaly ": 2.848173647013041, "Renin decreased ": 2.3042411770069817, "Renin increased ": 2.082308837258158, "Repetitive speech ": 3.1422521573791133, "Reproductive tract hypoplasia, male ": 3.442779540174401, "Residual urine volume increased ": 2.055622079171876, "Respiratory acidosis ": 3.118842580004438, "Respiratory alkalosis ": 2.2176592288517942, "Respiratory arrest ": 3.8915359153201576, "Respiratory depression ": 4.568320571719723, "Respiratory disorder neonatal ": 2.588730590460216, "Respiratory paralysis ": 7.1189753296775145, "Respiratory rate decreased ": 2.6556527511335397, "Respiratory therapy ": 5.1014313881746425, "Respiratory tract irritation ": 2.0044879529295985, "Resting tremor ": 2.0305199353929235, "Restlessness ": 2.3688837251653148, "Retained placenta or membranes ": 2.27748077074544, "Retained products of conception ": 15.331727054203268, "Retinal perivascular sheathing ": 5.2120338995345215, "Retinal pigmentation ": 2.277708364784209, "Retinogram abnormal ": 2.505632202639742, "Retinopathy of prematurity ": 2.757485007817944, "Retrognathia ": 3.850560056964408, "Retroperitoneal fibrosis ": 3.793581172214924, "Retroperitoneal haematoma ": 3.025162724547804, "Retroperitoneal haemorrhage ": 3.373220611658708, "Reversible cerebral vasoconstriction syndrome ": 2.247088394971932, "Reye's syndrome ": 2.08356463408125, "Rhabdomyolysis ": 3.246701802077788, "Rhinitis atrophic ": 2.5907254632306738, "Rhinotracheitis ": 2.5907254632306738, "Rhythm idioventricular ": 2.976063820706978, "Rickets ": 2.489100169809212, "Right aortic arch ": 7.9823439037603166, "Right ventricle outflow tract obstruction ": 3.1582598847212897, "Right ventricular hypertrophy ": 2.250110311145208, "Roseola ": 4.066377393236062, "Rubella ": 3.3960287103709885, "Rubella antibody negative ": 5.9756089375334325, "Salivary gland enlargement ": 3.7943728185512704, "Salivary gland mass ": 5.039246345822313, "Salivary hypersecretion ": 2.8299942871306256, "Scab ": 3.151428518472483, "Scaphocephaly ": 6.508249131985286, "School refusal ": 2.7089287803149595, "Scleral degeneration ": 3.615082672656949, "Scleral discolouration ": 3.058796406159473, "Scleral disorder ": 2.290718289316207, "Scleral pigmentation ": 3.390987587429732, "Scleromalacia ": 4.492837504195562, "Screaming ": 2.3745870566426714, "Scrotal disorder ": 2.539441762444792, "Scrotal haematoma ": 2.6473914494403386, "Seborrhoea ": 3.666842685011703, "Seizure ": 2.489717367346657, "Seizure anoxic ": 2.0600612252546204, "Selective eating disorder ": 2.62321703963181, "Self esteem decreased ": 3.711796527900934, "Self esteem inflated ": 3.018048574023795, "Self-destructive behaviour ": 3.301920383756484, "Self-induced vomiting ": 3.711071323108152, "Self-medication ": 4.047073104098589, "Semen analysis abnormal ": 5.518972311993257, "Semen viscosity abnormal ": 4.087854129026545, "Semen viscosity decreased ": 9.169036285391323, "Semen volume decreased ": 16.462340495407062, "Sensory integrative dysfunction ": 3.9844657603791687, "Separation anxiety disorder ": 3.79363972685902, "Septo-optic dysplasia ": 3.6909512834391984, "Septum pellucidum agenesis ": 2.946876774685152, "Serotonin syndrome ": 4.175173704204188, "Serpiginous choroiditis ": 9.224438259435836, "Serratia bacteraemia ": 5.778443613463153, "Serum serotonin decreased ": 2.0384881070613017, "Serum serotonin increased ": 2.967043443635618, "Serum sickness ": 2.8972038031510987, "Serum sickness-like reaction ": 4.630565987304372, "Sex hormone binding globulin increased ": 3.3106508746180974, "Sexual abuse ": 2.3277973666180256, "Sexual dysfunction ": 4.219860469532605, "Sexual inhibition ": 3.363071307471851, "Shared psychotic disorder ": 2.739337169947462, "Shock ": 3.461147074669838, "Shock symptom ": 4.379498629510223, "Shone complex ": 3.77657001277882, "Shoplifting ": 2.05052867485809, "Sigmoidoscopy abnormal ": 2.5907254632306738, "Similar reaction on previous exposure to drug ": 2.8503638494542263, "Single umbilical artery ": 2.4116525451543898, "Sinoatrial block ": 3.3210446427369886, "Sinus arrest ": 3.665851354021635, "Sinus bradycardia ": 3.612877904159472, "Sinus node dysfunction ": 2.2474099696486927, "Sinus tachycardia ": 2.274503916784505, "Skeletal dysplasia ": 2.0464318866351654, "Skin erosion ": 2.0997472573757374, "Skin hypoplasia ": 2.158702033383775, "Skin malformation ": 4.087854129026545, "Skin necrosis ": 3.103904254665292, "Skin oedema ": 2.025713421457311, "Skin test negative ": 14.090613018135617, "Skin test positive ": 6.845207254844766, "Skin turgor decreased ": 2.230215879687024, "Sleep attacks ": 2.018703857925951, "Sleep terror ": 3.0040748816687155, "Slow response to stimuli ": 2.992394011236041, "Small intestine carcinoma ": 3.057660323197817, "Social ": 4.864214213955248, "Social avoidant behaviour ": 2.946083142596406, "Social problem ": 4.612538747649669, "Soft tissue necrosis ": 2.2961430603263304, "Soliloquy ": 2.309302617868032, "Somnambulism ": 2.916047669671962, "Somnolence neonatal ": 5.159839539581868, "Sopor ": 4.910823340227829, "Specific gravity urine abnormal ": 3.787364818909382, "Speech disorder ": 2.0742455837524605, "Speech disorder developmental ": 7.489764164517793, "Speech sound disorder ": 3.899849023501064, "Sperm analysis abnormal ": 3.5148518229747605, "Sperm concentration decreased ": 4.944488428517633, "Sperm concentration zero ": 3.791598180341608, "Spermatocele ": 2.059807064143012, "Spermatogenesis abnormal ": 3.633047121257831, "Spermatozoa abnormal ": 3.253302696462397, "Spermatozoa progressive motility decreased ": 3.05826723229333, "Sphincter of Oddi dysfunction ": 4.571983757171695, "Spina bifida ": 9.307881668398927, "Spina bifida occulta ": 6.846316635349547, "Spinal anaesthesia ": 2.075593092528214, "Spinal claudication ": 3.0390232848659395, "Spinal cord haematoma ": 2.4124778320994578, "Spinal cord injury cauda equina ": 4.705583054188087, "Spinal cord injury lumbar ": 2.946876774685152, "Spinal cord lipoma ": 4.406448101978552, "Spinal subdural haematoma ": 2.42382439768555, "Sprue-like enteropathy ": 172.7288228115046, "Staring ": 2.293455876797243, "Stereotypy ": 2.145870014739728, "Steroid withdrawal syndrome ": 2.6015593138509443, "Stevens-Johnson syndrome ": 3.639609527367122, "Sticky skin ": 2.6900865223538863, "Stoma site erythema ": 2.59950973928883, "Stoma site inflammation ": 2.2274077408538293, "Strabismus ": 3.0740171733859394, "Strabismus congenital ": 7.878652582336181, "Strangury ": 2.094421477818836, "Strawberry tongue ": 3.312671505069676, "Stress cardiomyopathy ": 2.747675599450008, "Stridor ": 2.8247031944229346, "Stupor ": 3.724517642424073, "Subacute cutaneous lupus erythematosus ": 2.973498864588808, "Subacute sclerosing panencephalitis ": 2.5173319162917376, "Subcutaneous haematoma ": 2.3739751561721523, "Subdural haematoma evacuation ": 2.6663739977605343, "Subdural haemorrhage ": 2.301758699086143, "Subglottic laryngitis ": 2.278004847841669, "Substance abuse ": 2.946008259991852, "Substance abuser ": 10.500747080010026, "Substance dependence ": 6.331813041635209, "Substance use disorder ": 4.335625219119751, "Subvalvular aortic stenosis ": 5.545978172562894, "Sudden cardiac death ": 2.295596642627926, "Sudden onset of sleep ": 2.139047106151979, "Suffocation feeling ": 2.7355252856779115, "Suicidal behaviour ": 2.4893591276071683, "Suicidal ideation ": 2.011204755751704, "Suicide attempt ": 3.575924605264492, "Superficial injury of eye ": 2.516331049844454, "Suspected counterfeit product ": 2.195594692323787, "Suspected product contamination ": 5.293428798754087, "Suspected product quality issue ": 9.311970023165166, "Suspected suicide ": 3.307375996439719, "Suspected suicide attempt ": 3.39784936207953, "Suspected transmission of an infectious agent via product ": 2.720852107062384, "Suture insertion ": 2.192150282390372, "Swollen tongue ": 2.116307865719181, "Symmetrical drug-related intertriginous and flexural exanthema ": 3.3492101612946694, "Sympathomimetic effect ": 2.8576095853763683, "Symptom masked ": 2.1328766063100795, "Syndactyly ": 3.971983335530452, "Synostosis ": 2.792889305099717, "Synovial fluid white blood cells positive ": 7.228054958425599, "Systemic bacterial infection ": 2.119843710264686, "Systolic hypertension ": 2.8035285066803484, "Tachycardia foetal ": 3.427714936082394, "Tachycardia induced cardiomyopathy ": 3.5657892944655663, "Tachyphrenia ": 2.043534684895, "Tachypnoea ": 2.183055231535856, "Talipes ": 7.1162154846721055, "Tardive dyskinesia ": 2.524078419549817, "Tear discolouration ": 2.8888362465479496, "Tendon discomfort ": 3.68882999456238, "Tendon disorder ": 3.0010830691566244, "Tendon injury ": 7.488684495059885, "Tendon pain ": 3.381198426861797, "Tendon rupture ": 6.527613565727274, "Tendonitis ": 3.0915212672759, "Tension ": 2.37480451898001, "Teratospermia ": 2.704189143603206, "Terminal dribbling ": 6.404820898709732, "Testicular atrophy ": 4.189697507565455, "Testicular disorder ": 2.312823035789437, "Testicular failure ": 17.602001417614215, "Testicular pain ": 2.120929254609536, "Testis cancer ": 8.981949558503054, "Tetany ": 2.038096788667631, "Tethered cord syndrome ": 3.477477905696565, "Tethered oral tissue ": 2.5071816331976864, "Theft ": 2.3324848978728823, "Therapeutic drug monitoring analysis not performed ": 2.9100638210069447, "Therapeutic procedure ": 2.3007614168979083, "Therapeutic product effect increased ": 3.841837828361753, "Therapeutic product effect prolonged ": 4.393233777036584, "Therapeutic product ineffective for unapproved indication ": 2.301578549087566, "Therapeutic response changed ": 3.6945677666643375, "Therapeutic response increased ": 9.812603943749654, "Therapeutic response prolonged ": 5.026191923702681, "Therapeutic response unexpected ": 2.3918530538253098, "Thermometry abnormal ": 2.2142953271576955, "Thinking abnormal ": 2.037845156948818, "Third stage postpartum haemorrhage ": 2.0925266228089137, "Thought insertion ": 2.2450342229325893, "Throat cancer ": 3.4907187593180984, "Throat irritation ": 2.9079386216640515, "Thrombocytopenia neonatal ": 2.470150612661808, "Thrombocytopenic purpura ": 2.431601503245219, "Thyroid cancer ": 2.2317902343306857, "Thyroxine free decreased ": 2.504065261972996, "Thyroxine free increased ": 2.4888548247948585, "Thyroxine increased ": 2.1099780843773632, "Tic ": 3.3677228096086265, "Tobacco abuse ": 2.7522659942779586, "Tobacco poisoning ": 8.447912192520246, "Tobacco user ": 2.327324288687125, "Toe walking ": 4.272651510480063, "Tongue biting ": 2.5666048382896545, "Tongue coated ": 2.1275600443488623, "Tongue discolouration ": 5.391392431656931, "Tongue discomfort ": 2.538590796726074, "Tongue erythema ": 2.5098855509792592, "Tongue movement disturbance ": 2.307371102598474, "Tongue oedema ": 5.380345900740148, "Tongue pruritus ": 2.43261197163443, "Tonic clonic movements ": 2.0781264415650127, "Tonic convulsion ": 2.164932575284262, "Tooth agenesis ": 2.8785313480536923, "Tooth discolouration ": 10.29028265868072, "Tooth erosion ": 2.5039820032289364, "Topical steroid withdrawal reaction ": 4.724399646158816, "Torsade de pointes ": 6.399700596818088, "Total cholesterol/HDL ratio abnormal ": 3.615082672656949, "Tourette's disorder ": 3.597453321039998, "Toxic anterior segment syndrome ": 7.2211412869379314, "Toxic encephalopathy ": 6.172087907267465, "Toxic epidermal necrolysis ": 3.2390010841499235, "Toxic shock syndrome ": 2.291196524396278, "Toxic skin eruption ": 2.766928412793941, "Toxicity to various agents ": 4.170444836927049, "Toxicologic test abnormal ": 5.890579729766149, "Tracheal calcification ": 6.8031563798956105, "Tracheal obstruction ": 2.329282992563667, "Tracheal oedema ": 3.3437678202669416, "Tracheobronchitis bacterial ": 2.992703786062721, "Transferrin saturation decreased ": 2.2160764821872454, "Transmission of an infectious agent via product ": 4.610415708640639, "Transposition of the great vessels ": 5.140278249338905, "Transurethral resection syndrome ": 3.615082672656949, "Traumatic delivery ": 3.442779540174401, "Tremor neonatal ": 2.256157837439806, "Tri-iodothyronine free increased ": 2.169514759494804, "Tri-iodothyronine increased ": 2.68425082437952, "Trichoglossia ": 4.189697507565455, "Trichotillomania ": 2.562270527944284, "Trismus ": 2.6259034489140234, "Trousseau's sign ": 2.4172669215511355, "Truncus arteriosus persistent ": 2.4448318395062865, "Tryptase ": 7.510767283920724, "Tryptase decreased ": 7.461888341814831, "Tryptase increased ": 6.075504310740033, "Tuberculoma of central nervous system ": 2.445925557607906, "Tubulointerstitial nephritis ": 2.317117871052144, "Tympanoplasty ": 2.2142953271576955, "Type 1 lepra reaction ": 2.040534036553507, "Type 2 lepra reaction ": 2.1971999613674265, "Type I hypersensitivity ": 4.3693709790579325, "Type II hypersensitivity ": 3.891465979519322, "Type IV hypersensitivity reaction ": 3.279767481563943, "Ulcerated haemangioma ": 2.0925266228089137, "Umbilical hernia ": 2.0762885789851726, "Univentricular heart ": 2.3437301815919573, "Unmasking of previously unidentified disease ": 2.0204132437341378, "Unresponsive to stimuli ": 2.277073976066646, "Unwanted awareness during anaesthesia ": 2.735554988190805, "Upper respiratory tract irritation ": 2.277577993366569, "Urinary bladder suspension ": 2.1476805008371294, "Urinary casts ": 2.070447818919116, "Urinary hesitation ": 2.499815077900107, "Urinary retention ": 2.3085393354672585, "Urinary tract malformation ": 2.831712131471681, "Urine amphetamine positive ": 2.6961666124093897, "Urine bilirubin increased ": 2.1447791014765603, "Urine calcium decreased ": 3.601654780680706, "Urine chloride increased ": 3.487298748185552, "Urine flow decreased ": 2.85677048486426, "Urine osmolarity decreased ": 6.360958639031157, "Urine osmolarity increased ": 3.0570289746099717, "Urine output decreased ": 2.1201246865652403, "Urine potassium increased ": 2.224121452268076, "Urine sodium decreased ": 2.741472777367305, "Urine sodium increased ": 2.774053073866298, "Urticaria ": 2.14855599175597, "Urticaria papular ": 2.3526150684378715, "Uterine atony ": 2.790604720356131, "Uterine cancer ": 4.87186599063252, "Uterine dilation and curettage ": 7.563127125586946, "Uterine hyperstimulation ": 11.009382794528372, "Uterine hypertonus ": 3.635287123047323, "Uterine perforation ": 3.859879244102083, "Uterine rupture ": 9.571607644547427, "VACTERL syndrome ": 3.206012394354377, "Vaccine virus shedding ": 2.8576095853763683, "Vacuum extractor delivery ": 4.9387811580724525, "Vancomycin infusion reaction ": 14.45352933436712, "Varicella ": 13.544004575954627, "Varicella post vaccine ": 44.486327721891634, "Varicella virus test negative ": 2.182707492679382, "Varicocele ": 2.5955461117514167, "Vascular purpura ": 3.8833284020138654, "Vascular resistance systemic increased ": 4.793129411962667, "Vascular stent occlusion ": 2.599098033268341, "Vasculitis necrotising ": 2.2058289165384624, "Vasectomy ": 2.431575004969513, "Vasoconstriction ": 3.4671505055448164, "Vasodilation procedure ": 2.0563873272694297, "Vasoplegia syndrome ": 3.1979124410438864, "Vasospasm ": 2.9213072083710547, "Velopharyngeal incompetence ": 4.147715741662421, "Ventricular arrhythmia ": 3.091036117831784, "Ventricular asystole ": 2.253084019419624, "Ventricular fibrillation ": 3.1121852684431253, "Ventricular flutter ": 3.913732912441447, "Ventricular hypertrophy ": 2.1462261752809484, "Ventricular hypoplasia ": 2.413910384021141, "Ventricular septal defect ": 5.98437748005421, "Ventricular tachyarrhythmia ": 2.0411844031868918, "Ventricular tachycardia ": 3.2956698300438942, "Vesicoureteric reflux ": 2.2990917653458, "Vessel puncture site inflammation ": 5.76590816283194, "Vessel puncture site pain ": 2.182707492679382, "Victim of chemical submission ": 10.942081740626808, "Victim of homicide ": 3.875373024164392, "Victim of sexual abuse ": 4.329886383123141, "Violence-related symptom ": 2.289713277701801, "Visceral congestion ": 2.203448711752774, "Visceral oedema ": 2.792889305099717, "Visual acuity reduced transiently ": 2.5818766842578027, "Visual perseveration ": 3.3530131450886724, "Visual tracking test abnormal ": 2.8888362465479496, "Visuospatial deficit ": 6.133797719085272, "Vital dye staining cornea present ": 3.615082672656949, "Vitamin B1 decreased ": 2.218024882384535, "Vitamin B6 increased ": 2.397730974771322, "Vitamin K decreased ": 2.4674108568917084, "Vitamin K deficiency ": 6.946393816732602, "Vitello-intestinal duct remnant ": 2.2503218089250407, "Von Willebrand's factor antibody positive ": 7.0424728888252455, "Von Willebrand's factor inhibition ": 14.07430130606686, "Vulval oedema ": 2.527309505797336, "Vulvovaginal burning sensation ": 4.543923025530843, "Vulvovaginal discomfort ": 3.707920699882663, "Vulvovaginal dryness ": 2.716524636869612, "Vulvovaginal erythema ": 3.952273887291944, "Vulvovaginal exfoliation ": 10.08921392241555, "Vulvovaginal injury ": 4.905367865470461, "Vulvovaginal pain ": 2.0586039416863424, "Vulvovaginal pruritus ": 2.211223070873932, "Vulvovaginal rash ": 2.8927176922238345, "Vulvovaginal swelling ": 2.538092675704668, "Water intoxication ": 4.783466251645664, "Waxy flexibility ": 2.3344495938692265, "Weight decrease neonatal ": 2.0895536841468973, "Withdrawal arrhythmia ": 4.406448101978552, "Withdrawal bleed ": 3.082193078384861, "Withdrawal hypertension ": 2.277577993366569, "Withdrawal syndrome ": 5.768568903432912, "Wrong dosage form ": 4.826380696809855, "Wrong dose ": 3.1468294319621517, "Wrong drug ": 4.908255043006962, "Wrong patient received product ": 2.5538815374624657, "Wrong rate ": 10.099760554073583, "Wrong schedule ": 2.596795586362377, "Wrong strength ": 4.836185055698578, "Wrong technique in device usage process ": 2.617717026796781, "Wrong technique in product usage process ": 2.3016747022859603, "Yellow fever ": 3.444647014378324, "Yellow fever vaccine-associated neurotropic disease ": 28.122271498465786, "Yellow fever vaccine-associated viscerotropic disease ": 8.67536490504203}
\ No newline at end of file
+{"Completed suicide": 51.41570996496304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1217.json
new file mode 100644
index 00000000000..dafbf503ac9
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1217.json
@@ -0,0 +1 @@
+{"Exposure during pregnancy": 46.89507925655583}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1218.json
new file mode 100644
index 00000000000..ab572c8de76
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1218.json
@@ -0,0 +1 @@
+{"Acute kidney injury": 2.132787931469786, "Disease progression": 4.5333313600465255, "Hypercalcaemia": 39.44529671253941, "Hypocalcaemia": 65.58578364951654, "Malignant neoplasm progression": 7.868406437144278, "Metastases to bone": 29.374429379307216, "Osteonecrosis of jaw": 390.7119213060007}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1219.json
new file mode 100644
index 00000000000..e52928f045e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1219.json
@@ -0,0 +1 @@
+{"Diarrhoea": 2.788184242509109, "Lactic acidosis": 61.4950458281488}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/122.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/122.json
index a2239e0120b..0891b1edc65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/122.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/122.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 60.71043296661498, "Acute myocardial infarction ": 23.618047233122965, "Acute pulmonary oedema ": 5.511566529707905, "Amnesia ": 2.891006817442729, "Angina pectoris ": 12.503593489808305, "Angina unstable ": 100.22710915779828, "Angioplasty ": 45.84325643231059, "Aortic stenosis ": 10.85419364374887, "Arrhythmia ": 2.763557013166295, "Arterial occlusive disease ": 18.58232363788637, "Arteriosclerosis ": 44.49856676448125, "Arteriosclerosis coronary artery ": 51.45619721533965, "Atrial fibrillation ": 10.241911629514291, "Atrial flutter ": 11.752151480888234, "Atrioventricular block ": 4.80374648200177, "Atrioventricular block complete ": 7.415844798664104, "Blindness ": 4.482629514624176, "Cardiac arrest ": 5.140590329875609, "Cardiac disorder ": 28.943638573777896, "Cardiac failure ": 3.788807156553192, "Cardiac failure congestive ": 104.4619512017606, "Cardiac operation ": 14.58077631782412, "Cardiac pacemaker insertion ": 19.937834517446312, "Cardiac valve disease ": 11.853169181862691, "Cardiac ventricular thrombosis ": 11.341652948128472, "Cardio-respiratory arrest ": 3.392282987161156, "Cardiogenic shock ": 5.5947484536308805, "Cardiomegaly ": 11.894069204386057, "Cardiomyopathy ": 33.29832491463044, "Cardiovascular disorder ": 34.3377536578613, "Carotid artery disease ": 34.88417120150129, "Catheterisation cardiac ": 21.67903078095096, "Cerebral infarction ": 2.357329880691526, "Cerebrovascular accident ": 22.683160374407223, "Cerebrovascular disorder ": 21.709715064212386, "Chest pain ": 2.9880563191681166, "Chronic obstructive pulmonary disease ": 2.151260034691944, "Coronary arterial stent insertion ": 55.372997306132895, "Coronary artery bypass ": 116.1391656005156, "Coronary artery disease ": 169.08569785564652, "Coronary artery occlusion ": 16.115326487772382, "Coronary artery stenosis ": 8.483288827221196, "Diabetic retinopathy ": 6.479268986983397, "Dilated cardiomyopathy ": 21.715518874769412, "Fluid retention ": 4.868525016089837, "Heart rate irregular ": 5.271241572513962, "Hemiparesis ": 3.0169948322825304, "Hemiplegia ": 2.893038001513855, "Hyperlipidaemia ": 15.304757636588963, "Hypertension ": 2.128176983403482, "Hypertensive heart disease ": 27.68616959106914, "Implantable defibrillator insertion ": 72.10628156499364, "Injury ": 6.082735841414787, "Ischaemia ": 10.738798988022532, "Ischaemic cardiomyopathy ": 169.05160863372032, "Ischaemic stroke ": 2.4155015201814027, "Lacunar infarction ": 11.344734333160911, "Left ventricular dysfunction ": 5.097039210258387, "Macular oedema ": 26.75152210463802, "Mitral valve incompetence ": 8.707804642688046, "Myocardial infarction ": 63.61789877734254, "Myocardial injury ": 147.73120757729404, "Myocardial ischaemia ": 105.0980192728626, "Oedema ": 2.3627474756270748, "Pericardial effusion ": 3.9064900829692415, "Peripheral vascular disorder ": 5.234960823364357, "Pleural effusion ": 5.824423803126988, "Pulmonary hypertension ": 4.95285884304413, "Pulmonary oedema ": 7.574492324585017, "Silent myocardial infarction ": 133.53069705627797, "Sinus node dysfunction ": 23.844714122606327, "Stent placement ": 73.18778338968191, "Sudden cardiac death ": 12.478341212113836, "Supraventricular tachycardia ": 9.139617413033282, "Transient ischaemic attack ": 23.62075395691535, "Ventricular fibrillation ": 4.765279158410529, "Ventricular tachycardia ": 7.567434640734304}
\ No newline at end of file
+{"Alanine aminotransferase abnormal": 6.4278130349641085, "Alanine aminotransferase increased": 3.9275978861122938, "Alopecia": 11.52851498970459, "Alopecia areata": 3.5587066548938435, "Anal incontinence": 4.843845471241635, "Back disorder": 2.950170363660659, "Balance disorder": 7.996909550598354, "Band sensation": 23.5808206978337, "Bladder disorder": 17.765895855909957, "Bladder dysfunction": 10.468867883142206, "Blood test abnormal": 2.0208139708240136, "Blood thyroid stimulating hormone decreased": 2.1578896725735293, "Breast cancer female": 3.647510563835208, "Burning sensation": 2.3965811461273714, "Carpal tunnel syndrome": 6.670900422854494, "Central nervous system lesion": 17.894694885581256, "Cerebral disorder": 2.4275278959312487, "Cholecystectomy": 2.4090626936720563, "Cognitive disorder": 3.961541347446057, "Colitis microscopic": 6.419709516771997, "Condition aggravated": 2.999665336599381, "Coronavirus infection": 2.1496519565550347, "Cystitis": 2.993392101727143, "Decreased interest": 25.22844244537752, "Decubitus ulcer": 2.847924794463969, "Defaecation urgency": 2.621093077408025, "Demyelination": 3.10289425541954, "Dental caries": 3.285563600565066, "Depressed mood": 3.7642857418753017, "Depression": 3.065452824785652, "Diarrhoea": 2.180099191393898, "Diffuse alopecia": 4.692491290429671, "Diplopia": 2.290242975455316, "Dysaesthesia": 2.1201063919752463, "Dysgraphia": 2.520265838200848, "Dysstasia": 2.589664259707972, "Electric shock sensation": 2.5672429965761374, "Expanded disability status scale score increased": 40.421150494783, "Exposure during pregnancy": 2.3049688225369023, "Fall": 4.819101026266892, "Fine motor skill dysfunction": 2.5222261475367898, "Foot operation": 2.9381704622259286, "Frequent bowel movements": 2.2391407422368284, "Frustration tolerance decreased": 2.354134427603052, "Functional gastrointestinal disorder": 3.323534194999604, "Furuncle": 2.5018435143340563, "Gait disturbance": 5.30020024714883, "Gait inability": 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"Kidney infection": 3.403758391958024, "Lhermitte's sign": 38.16629831937677, "Liver function test increased": 4.5160292700424245, "Loss of personal independence in daily activities": 2.953966090328294, "Lung adenocarcinoma": 2.928485174599576, "Lymphocyte count abnormal": 11.739164299153028, "Lymphocyte count decreased": 9.06893602700145, "Lymphocyte count increased": 3.8172761736016434, "Lymphopenia": 12.870535835286068, "Madarosis": 9.240141058208, "Magnetic resonance imaging abnormal": 33.03743141943891, "Memory impairment": 3.968119455313777, "Mental impairment": 2.1406167489554577, "Micturition urgency": 4.439556515164928, "Mobility decreased": 5.578299516750946, "Monocyte count increased": 4.329455765541903, "Motor dysfunction": 2.0872173526915976, "Movement disorder": 3.123824406102803, "Multiple sclerosis": 142.97661443525362, "Multiple sclerosis pseudo relapse": 36.98567155641817, "Multiple sclerosis relapse": 442.2153452914684, "Muscle spasticity": 11.39281275245328, "Muscular weakness": 3.0100141923429597, "Musculoskeletal disorder": 4.449610766319105, "Nail disorder": 3.7817390360638634, "Nephrolithiasis": 2.645091506088603, "Nerve compression": 2.4702443207889035, "Neuralgia": 2.1950529773093166, "Neurogenic bladder": 4.332997045852368, "Neuropathy peripheral": 4.482843728233076, "Onychoclasis": 6.330094121484772, "Onychomadesis": 4.581009849075122, "Optic neuritis": 16.354029406573662, "Ovarian cancer": 2.0561271761127498, "Paraesthesia": 3.2014366368189435, "Paraparesis": 4.25204866183232, "Peroneal nerve palsy": 8.338161126822724, "Pollakiuria": 2.0044547888472484, "Polyneuropathy": 6.214146362741984, "Product dose omission in error": 16.134035928206714, "Product dose omission issue": 5.372121428470943, "Progressive multiple sclerosis": 96.6633403339054, "Pustular psoriasis": 2.4652773125089773, "Relapsing-remitting multiple sclerosis": 37.09277527668204, "SARS-CoV-2 test positive": 2.7378812138530573, "Sciatica": 3.404037373776133, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1220.json
new file mode 100644
index 00000000000..95832749d41
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1220.json
@@ -0,0 +1 @@
+{"Abscess": 13.327878876799396, "Actinomycosis": 455.2063790686895, "Acute kidney injury": 3.2780515268582646, "Anaemia": 2.862494021140573, "Aortic arteriosclerosis": 55.2295906269168, "Aortic valve incompetence": 26.34132372946341, "Arteriosclerosis": 9.835765219158038, "Arthritis": 2.0453810811446984, "Arthropathy": 2.430895632992411, "Atelectasis": 23.739961690060543, "Blood alkaline phosphatase increased": 2.9294284995589384, "Blood creatinine increased": 5.489353047981829, "Blood urea increased": 10.988333564731985, "Bone disorder": 41.80690296883919, "Bone lesion": 103.63858104400656, "Bone pain": 3.57574804264202, "Bone sequestrum": 1451.4647828344212, "Bronchitis": 4.231717490299132, "Cardiac failure congestive": 2.054423757882481, "Cardiomegaly": 18.884744779447683, "Cataract": 4.2491718357283785, "Cellulitis": 2.6517937366580027, "Cholelithiasis": 5.003313386098775, "Chronic obstructive pulmonary disease": 4.592053406444897, "Circulatory collapse": 3.399830281282492, "Compression fracture": 42.66425174097731, "Deep vein thrombosis": 2.0029373390952188, "Dehydration": 2.328835897484585, "Haematocrit decreased": 6.303005249763632, "Haemoglobin decreased": 2.360016145650666, "Hypocalcaemia": 19.713913298984803, "Hypokalaemia": 2.356209244741283, "Impaired healing": 5.11357132893882, "Malignant neoplasm progression": 5.594598733873204, "Metastases to bone": 20.61406513089984, "Metastases to liver": 5.033653834751213, "Osteomyelitis": 35.10675871764828, "Osteonecrosis": 5.591603834989503, "Osteonecrosis of jaw": 194.4531119845519, "Pain in jaw": 9.804681688608202, "Platelet count decreased": 2.100403131220224, "Red blood cell count decreased": 4.146037488744774, "Tooth disorder": 10.949681459368056, "Tooth extraction": 91.64366988596448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1221.json
new file mode 100644
index 00000000000..3e2feabf42d
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1221.json
@@ -0,0 +1 @@
+{"Drug interaction": 9.638167667220303, "Hypersensitivity": 2.2341482219216244, "Migraine": 4.0665620084698375, "Seizure": 8.947587382112076, "Vertigo": 3.995681524225828, "Weight decreased": 4.140551471611718, "Weight increased": 6.5412668695867495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1222.json
new file mode 100644
index 00000000000..b116b4f6627
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1222.json
@@ -0,0 +1 @@
+{"Abnormal behaviour": 10.15880150495769, "Altered state of consciousness": 4.500602372188896, "Anuria": 18.93129004190845, "Bipolar disorder": 47.7760182561827, "Blood creatine phosphokinase increased": 3.452511679802398, "Blood urea increased": 10.683918867731062, "Bradycardia": 2.557126501671216, "Depressed level of consciousness": 5.605950268983202, "Drug eruption": 7.800527925233679, "Drug ineffective": 4.661057571783706, "Drug intolerance": 5.296459878887359, "Drug reaction with eosinophilia and systemic symptoms": 7.465738990781831, "Epilepsy": 11.425929562407545, "Exposure during pregnancy": 4.932643594157653, "Foetal exposure during pregnancy": 2.741425171075988, "Hepatic function abnormal": 2.6465515709358494, "Leukopenia": 2.571307958491401, "Mania": 14.720482474685856, "Migraine": 4.844660135959851, "Multiple-drug resistance": 47.622253705920464, "Muscle rigidity": 14.557648724337986, "Narcolepsy": 118.53825262590009, "Partial seizures": 26.277264727374625, "Product quality issue": 7.581383850589211, "Product use in unapproved indication": 5.012587578191644, "Psychotic disorder": 7.525407504306917, "Sedation complication": 31.296084691284683, "Seizure": 6.66631430307889, "Somnolence": 3.321195457239098, "Stevens-Johnson syndrome": 7.613532078378639, "Substance-induced psychotic disorder": 120.2758147956934, "Thrombocytopenia": 2.204431151223429, "Tonic convulsion": 106.94908801847065, "Toxicity to various agents": 2.055609582391482, "Treatment failure": 5.101233045034793, "Tubulointerstitial nephritis": 16.623826372446818, "Urinary tract infection": 3.988565454538741, "Weight increased": 4.469000600615219, "White blood cell count increased": 6.167816477328346}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1223.json
new file mode 100644
index 00000000000..2ca209a1d1b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1223.json
@@ -0,0 +1 @@
+{"Abdominal hernia": 5.164427599561275, "Abdominal mass": 4.012393880462157, "Abnormal loss of weight": 2.593697544139217, "Acoustic neuroma": 11.876445600458094, "Acquired mixed hyperlipidaemia": 489.94630389484894, "Actinic keratosis": 25.114607041160724, "Acute left ventricular failure": 7.1992385345176455, "Acute respiratory failure": 2.0040366882893186, "Acute sinusitis": 38.49046683928115, "Adjustment disorder": 30.96601445600161, "Adverse event": 2.309491560303547, "Age-related macular degeneration": 5.637977811393763, "Allergy to vaccine": 13.0498302929037, "Anaemia of chronic disease": 5.040994189851421, "Antibiotic therapy": 31.48026766407909, "Anticoagulant therapy": 36.981120219887366, "Anxiety": 2.8969539826207047, "Anxiety disorder": 4.291187070023269, "Aortic aneurysm": 5.545072419856558, "Aortic arteriosclerosis": 16.424780073217494, "Aortic dilatation": 6.494443494710285, "Aortic disorder": 10.557504203278867, "Aortic stenosis": 3.1366037193466263, "Aortic valve sclerosis": 9.830322229263365, "Appendicectomy": 6.517134159264232, "Arteriosclerosis": 3.138886773829273, "Arteriosclerosis coronary artery": 7.703473999972534, "Arthritis": 4.156189137033174, "Arthropod bite": 13.503982961890406, "Arthroscopy": 11.368611215740655, "Astigmatism": 19.59732373409444, "Atelectasis": 2.318115654937399, "Atrial flutter": 2.027640543499685, "Atrophic vulvovaginitis": 33.04300232734704, "Autoimmune disorder": 2.837894299558909, "Autonomic neuropathy": 5.283170520147827, "Back disorder": 2.8643734347418857, "Barrett's oesophagus": 5.60265196099114, "Basal cell carcinoma": 2.8016962452777614, "Bell's palsy": 7.838468840533993, "Benign prostatic hyperplasia": 17.209291136147144, "Bladder disorder": 3.1585839038730263, "Blepharitis": 9.390135306904057, "Blindness": 8.260589427395859, "Blindness unilateral": 4.404750758477438, "Blood calcium abnormal": 4.66692952713714, "Blood cholesterol abnormal": 47.086650702910994, "Blood cholesterol increased": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1224.json
new file mode 100644
index 00000000000..18b06a83a95
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1224.json
@@ -0,0 +1 @@
+{"Application site erythema": 30.13450349102564, "Application site pain": 12.67780233131007, "Application site reaction": 39.556561252101694, "Application site scab": 458.819205636191, "Blister": 3.5442575108053176, "Decreased appetite": 2.6708066364486056, "Erythema": 4.986852495425467, "Erythema multiforme": 9.560866635513914, "Inflammation": 4.790901671129223, "Influenza like illness": 4.690176277945901, "Oropharyngeal pain": 2.079486191570606, "Scab": 135.764142320459, "Skin burning sensation": 9.35178344231789, "Skin reaction": 19.03068767252705, "Wound": 7.659344187584155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1225.json
new file mode 100644
index 00000000000..18a46407c86
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1225.json
@@ -0,0 +1 @@
+{"Diarrhoea": 4.664362395774028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1226.json
new file mode 100644
index 00000000000..e0f04b7bbcd
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1226.json
@@ -0,0 +1 @@
+{"Abdominal pain": 2.536820778793655, "Abdominal pain upper": 8.253573309960352, "Angina pectoris": 15.01791663778948, "Angioedema": 4.551821124708186, "Coronary artery thrombosis": 160.65552500694767, "Drug ineffective": 3.103816270187036, "Drug interaction": 2.22771476481896, "Dyspepsia": 8.012185363188555, "Epistaxis": 15.19584620684367, "Erythema": 4.047548272493715, "Product substitution issue": 27.06103239303645, "Pruritus": 7.784913261371754, "Rash": 2.746088260203167, "Urticaria": 9.606568970908452, "Vascular stent thrombosis": 138.0150982923855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1227.json
new file mode 100644
index 00000000000..0b580a71b72
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1227.json
@@ -0,0 +1 @@
+{"Abnormal behaviour": 4.974195543518177, "Abscess limb": 8.907174373435073, "Aggression": 7.693713985210725, "Agitation": 16.09520139701912, "Akathisia": 29.23638263451846, "Altered state of consciousness": 6.098538538996962, "Amnesia": 2.9605379745798617, "Antipsychotic drug level increased": 11.793153247741134, "Anxiety": 2.55641610942508, "Ataxia": 22.57490787699817, "Balance disorder": 5.496747060021855, "Blood pressure decreased": 3.847048937370293, "Blood pressure increased": 3.859726599169259, "Bradyphrenia": 5.382589566057559, "Cognitive disorder": 3.628932009166916, "Coma": 5.448804033078474, "Confusional state": 14.5999685816965, "Consciousness fluctuating": 23.833402679072265, "Coordination abnormal": 5.333590560366172, "Delirium": 15.587739702654378, "Delusion": 3.6048305583936657, "Depressed level of consciousness": 6.974873881044728, "Disorientation": 29.82390288543815, "Disturbance in attention": 3.193905399840759, "Dizziness": 2.9242847734686945, "Drug level decreased": 4.112976623075581, "Drug level increased": 4.2712946673072505, "Dysarthria": 58.70617919143494, "Dyskinesia": 7.768752914180816, "Dysstasia": 4.682801435551391, "Dystonia": 4.480892946158898, "Extrapyramidal disorder": 24.678070147681662, "Feeling drunk": 23.81473364229841, "Gait disturbance": 4.8049310242243966, "Hallucination, auditory": 3.010679029354051, "Hallucination, visual": 2.544636836470833, "Heart rate increased": 5.069417699783813, "Hypersomnia": 6.416259329163188, "Hypertension": 2.539219842087234, "Hypotension": 2.4755832259065245, "Hypotonia": 3.001666135916481, "Immediate post-injection reaction": 113.16399785885174, "Incoherent": 14.516592500646311, "Incorrect route of product administration": 2.897577996630229, "Injection related reaction": 30.009545814606085, "Injection site abscess": 105.09789913813586, "Injection site extravasation": 9.81296537995781, "Injection site haemorrhage": 8.814872713036596, "Injection site mass": 3.757335327248045, "Loss of consciousness": 2.6775752755546227, "Miosis": 7.962094257083629, "Muscle rigidity": 5.275722377631711, "Muscle twitching": 2.5134405385365186, "Neuroleptic malignant syndrome": 4.160085951465657, "Overdose": 2.8951672394409647, "Pallor": 4.007920658462364, "Post procedural complication": 88.53570773576514, "Post-injection delirium sedation syndrome": 3968.163149506781, "Prescribed overdose": 25.019653221165527, "Product administered at inappropriate site": 7.380180241670926, "Psychomotor hyperactivity": 18.421043368971645, "Psychotic disorder": 6.155587087679568, "Restless legs syndrome": 5.691738086625223, "Restlessness": 13.4418961201057, "Salivary hypersecretion": 4.116023395429085, "Schizophrenia": 21.36373084332392, "Sedation": 106.64327216150753, "Sedation complication": 16.4995846831076, "Sinus tachycardia": 4.280952019551647, "Somnolence": 13.286589224288536, "Sopor": 9.28064573873982, "Speech disorder": 11.555275411917076, "Stupor": 10.97224510541739, "Tachycardia": 4.088460723087828, "Tardive dyskinesia": 5.6349484121202185, "Unresponsive to stimuli": 7.945294085199056, "Urinary incontinence": 2.6666043959039936, "Vertigo": 2.57662937836009, "Weight increased": 3.4178019852734374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1228.json
new file mode 100644
index 00000000000..c0a2c5ef390
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1228.json
@@ -0,0 +1 @@
+{"Abnormal behaviour": 3.566399861795604, "Abnormal weight gain": 8.664802590360368, "Abulia": 6.440529739071105, "Accidental overdose": 2.174367119340546, "Acidosis": 2.216967025830745, "Acute psychosis": 5.174574349681914, "Affect lability": 2.343477978976052, "Aggression": 4.120879718859056, "Agitation": 4.668850229763304, "Agitation neonatal": 8.28936972127874, "Akathisia": 17.46367824396271, "Akinesia": 2.704758957505391, "Alanine aminotransferase increased": 4.010272484062591, "Alcohol abuse": 2.897917832979334, "Alcohol poisoning": 4.09410588870549, "Alcohol withdrawal syndrome": 8.77376466562783, "Alcoholism": 6.73902509706444, "Altered state of consciousness": 3.4411979518512434, "Amylase increased": 2.560621699453914, "Anger": 2.424903205000438, "Angle closure glaucoma": 2.476663455096601, "Anticholinergic syndrome": 4.0707804444432965, "Antidepressant drug level increased": 16.890541440676117, "Antipsychotic drug level increased": 4.8880740623079, "Apallic syndrome": 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"Blood prolactin increased": 21.685241915982584, "Blood sodium decreased": 2.450780305457465, "Blood triglycerides increased": 33.84626014211938, "Body mass index increased": 3.419602997968908, "Bradykinesia": 2.7018454460739987, "Bradyphrenia": 2.6534028205758537, "Brain death": 2.70301258780795, "Brain injury": 2.427785694793206, "Breast enlargement": 3.420498989317903, "Bruxism": 2.483291708957956, "Bundle branch block right": 2.09361369094556, "Cardiac hypertrophy": 3.188004540090515, "Catatonia": 14.01385406055225, "Cerebral atrophy": 2.798446420336941, "Cerebrovascular disorder": 3.912715065415471, "Cholelithiasis": 2.2814739803491992, "Choreoathetosis": 4.767504971440186, "Clonic convulsion": 3.15310569170505, "Clonus": 2.074164085782093, "Cogwheel rigidity": 17.53869953576088, "Coma": 5.732816550082031, "Communication disorder": 2.3856103067994647, "Completed suicide": 2.7594506840860022, "Craniocerebral injury": 2.2033645574720486, "Decreased interest": 2.7069383970640644, "Decubitus ulcer": 3.724063753471079, "Delirium": 5.092557345386584, "Delusion": 8.217355103437207, "Depressed level of consciousness": 2.901233265934018, "Depressive symptom": 2.4368056075384312, "Diabetes insipidus": 3.4326556602616947, "Diabetes mellitus": 27.945370773614137, "Diabetes mellitus inadequate control": 2.2571293419371847, "Diabetic coma": 49.46844437744479, "Diabetic complication": 3.612306794849199, "Diabetic foot": 2.969149638576205, "Diabetic hyperglycaemic coma": 6.794034007900975, "Diabetic hyperosmolar coma": 75.06022336659977, "Diabetic ketoacidosis": 9.708810155299544, "Diabetic ketosis": 15.38794202383344, "Diabetic nephropathy": 10.300323979748224, "Diabetic neuropathy": 19.57954386470773, "Diabetic retinopathy": 3.491502538606862, "Diet refusal": 5.387113282423931, "Disinhibition": 2.931223054429402, "Disorientation": 2.227140069878215, "Drooling": 10.59189724131937, "Drug interaction": 2.130968536104548, "Drug level increased": 2.7521604163721265, "Drug use 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increased": 2.405301742406869, "Trismus": 2.063182590581448, "Type 1 diabetes mellitus": 14.301828932237015, "Type 2 diabetes mellitus": 34.115576957815925, "Urinary hesitation": 10.658317809607908, "Urinary incontinence": 3.379143310864157, "Urinary retention": 2.6311103210662243, "Vascular dementia": 7.412748895653999, "Water intoxication": 22.635089173349705, "Weight increased": 19.36424138424285, "White blood cell count increased": 2.9689807592004023, "Withdrawal syndrome": 2.3421312800579845, "Wrong patient received product": 2.4635423448112053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1229.json
new file mode 100644
index 00000000000..6e98ee6184e
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1229.json
@@ -0,0 +1 @@
+{"Acute kidney injury": 2.921495966485069, "Cardiac failure": 8.67431969562131, "Constipation": 3.130077438763096, "Drug interaction": 7.829372144369054, "Hypokalaemia": 31.003792064069334, "Hyponatraemia": 7.082231516235132, "Prostate cancer": 19.69964984498989, "Rhabdomyolysis": 11.56432057170765}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/123.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/123.json
index b722b2752b1..b7b6201eaeb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/123.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/123.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 38.27116578786335, "Acute myocardial infarction ": 21.50512379412397, "Acute pulmonary oedema ": 6.5843825648219205, "Acute respiratory failure ": 2.3903323532447263, "Alanine aminotransferase increased ": 2.0078399660957147, "Amnesia ": 2.463285906066578, "Aneurysm ": 3.6539815259801465, "Angina pectoris ": 10.07954079592127, "Angina unstable ": 77.83761588051956, "Angiopathy ": 4.333558304004541, "Angioplasty ": 25.75840700252757, "Aortic aneurysm ": 2.5261139334429763, "Aortic arteriosclerosis ": 5.367409323557069, "Aortic stenosis ": 17.233442658468967, "Aortic valve disease ": 7.269905223714561, "Aortic valve incompetence ": 4.580170668540155, "Aortic valve replacement ": 18.602610553937968, "Aortic valve stenosis ": 10.39883154122372, "Arrhythmia ": 3.3864220168075776, "Arterial disorder ": 7.327198674532172, "Arterial occlusive disease ": 12.997503544288795, "Arterial stenosis ": 6.678563257384186, "Arteriosclerosis ": 29.9932414377477, "Arteriosclerosis coronary artery ": 40.77317616096587, "Aspartate aminotransferase increased ": 2.002514034589882, "Atrial fibrillation ": 10.33862560469207, "Atrial flutter ": 13.00861855186044, "Atrioventricular block ": 6.017028078682692, "Atrioventricular block complete ": 6.509628127960115, "Atrioventricular block first degree ": 4.489160933955906, "Atrioventricular block second degree ": 5.728504500486245, "Blindness ": 3.3290183326233627, "Blood alkaline phosphatase increased ": 2.3835883387006183, "Blood bilirubin increased ": 2.208542461144458, "Blood triglycerides increased ": 2.735051850598865, "Brain injury ": 3.917724158352318, "Brain stem infarction ": 11.845639041941055, "Brain stem stroke ": 9.931168679544324, "Bundle branch block ": 4.871043275993024, "Bundle branch block left ": 5.154379714731715, "Bundle branch block right ": 5.488581106330056, "Cardiac arrest ": 6.976068509320149, "Cardiac assistance device user ": 123.18733186227288, "Cardiac death ": 13.037123620844204, "Cardiac disorder ": 27.684924740229363, "Cardiac failure ": 7.0215774819115175, "Cardiac failure chronic ": 3.4220726169463966, "Cardiac failure congestive ": 144.4540653622416, "Cardiac hypertrophy ": 7.3568156913836145, "Cardiac murmur ": 3.039899499693559, "Cardiac operation ": 16.313545370563542, "Cardiac pacemaker insertion ": 25.08712462002974, "Cardiac tamponade ": 2.277359406197589, "Cardiac valve disease ": 15.201628810813183, "Cardiac ventricular thrombosis ": 11.47684906168181, "Cardio-respiratory arrest ": 6.213980049469706, "Cardiogenic shock ": 7.421890013339674, "Cardiomegaly ": 13.114856039998877, "Cardiomyopathy ": 25.77657123942545, "Cardiopulmonary failure ": 5.294740101758958, "Cardiovascular disorder ": 28.280664935486307, "Carotid artery disease ": 32.31122725560829, "Carotid artery occlusion ": 5.520725541068261, "Carotid artery stenosis ": 21.873323527850555, "Catheterisation cardiac ": 27.96274938235936, "Cerebellar infarction ": 2.545929628653369, "Cerebral infarction ": 2.830299260737553, "Cerebrovascular accident ": 24.03347993126246, "Cerebrovascular disorder ": 13.309273364352492, "Chest pain ": 2.3082807721063108, "Chronic obstructive pulmonary disease ": 2.211175090819899, "Cor pulmonale ": 24.225855822519204, "Coronary angioplasty ": 22.041970804782157, "Coronary arterial stent insertion ": 44.21262373050259, "Coronary artery bypass ": 118.96077847315031, "Coronary artery disease ": 179.02602553093664, "Coronary artery occlusion ": 16.685233151392737, "Coronary artery stenosis ": 5.277059551346465, "Coronary artery thrombosis ": 4.819469542878076, "Death ": 4.279523755190527, "Diabetic complication ": 3.221978887693275, "Diabetic retinopathy ": 5.475881645653248, "Diastolic dysfunction ": 10.627815105201469, "Dilated cardiomyopathy ": 24.4372415832342, "Disability ": 2.575245743437605, "Dyspnoea paroxysmal nocturnal ": 8.603117149973123, "Ejection fraction decreased ": 2.3196035920313878, "Electrocardiogram change ": 4.942959132239823, "Embolic stroke ": 3.4631106045619933, "End stage renal disease ": 2.847829702820295, "Fluid retention ": 7.802737628966721, "Fracture ": 2.406422488438323, "Generalised oedema ": 3.16527752348487, "Heart rate irregular ": 6.273238005579436, "Heart sounds abnormal ": 5.662628944136256, "Heart valve incompetence ": 7.480437648802755, "Heart valve replacement ": 8.088474615620378, "Hemiparesis ": 3.3782616450182954, "Hemiplegia ": 2.6499985934902237, "Hepatic cirrhosis ": 2.595557005903756, "Hepatic failure ": 3.236832711774552, "Hepatic necrosis ": 3.435162665874572, "High density lipoprotein decreased ": 5.018453519998397, "Humerus fracture ": 2.492301123866433, "Hyperlipidaemia ": 10.894237758081053, "Hypertensive cardiomyopathy ": 28.971509755519406, "Hypertensive heart disease ": 30.99793316451888, "Hypertrophic cardiomyopathy ": 3.912040721943266, "Hypervolaemia ": 6.426760338457346, "Hypoxic-ischaemic encephalopathy ": 11.517689810883622, "Implantable defibrillator insertion ": 67.76721455366767, "Injury ": 12.57712977984629, "Ischaemia ": 11.298375858973191, "Ischaemic cardiomyopathy ": 234.05620985013016, "Ischaemic stroke ": 3.742709476090834, "Jugular vein distension ": 9.058979089733969, "Lacunar infarction ": 16.58420049389253, "Left atrial enlargement ": 11.297753703386013, "Left ventricular dysfunction ": 6.683133943722663, "Left ventricular failure ": 6.345851504312924, "Left ventricular hypertrophy ": 7.09938559562857, "Leg amputation ": 4.68164557239068, "Macular oedema ": 50.570604294264726, "Mitral valve disease ": 15.396607845184848, "Mitral valve incompetence ": 9.88420787721383, "Mitral valve prolapse ": 5.6126197414567605, "Myocardial infarction ": 65.88708404164942, "Myocardial injury ": 181.7509825862903, "Myocardial ischaemia ": 75.73261401072858, "Obstruction ": 7.250883023933782, "Oedema ": 5.649473610403978, "Oedema peripheral ": 3.0749932058921328, "Orthopnoea ": 11.616204282460613, "Oxygen therapy ": 8.30495392094646, "Percutaneous coronary intervention ": 30.486712478463133, "Pericardial effusion ": 5.3884355503676105, "Peripheral arterial occlusive disease ": 3.595742729762115, "Peripheral vascular disorder ": 6.756682927408639, "Pleural effusion ": 7.120059347451, "Pulmonary hypertension ": 7.998518804061009, "Pulmonary oedema ": 10.488578994774208, "Renal artery stenosis ": 3.5803294054449943, "Renal failure ": 2.0501693966716874, "Respiratory failure ": 3.0820235222524754, "Silent myocardial infarction ": 101.08552263729445, "Sinus node dysfunction ": 22.91092917009161, "Stent placement ": 76.16923964738442, "Sudden cardiac death ": 16.255661799610106, "Supraventricular tachycardia ": 7.62513411611777, "Systolic dysfunction ": 4.647644783279799, "Toe amputation ": 2.205213782983147, "Transient ischaemic attack ": 22.866042068495744, "Traumatic lung injury ": 5.651198721492126, "Tricuspid valve incompetence ": 4.319504011342207, "Vascular graft ": 48.133238740483016, "Vascular occlusion ": 2.842262095458905, "Ventricular arrhythmia ": 4.790327141951398, "Ventricular fibrillation ": 6.730305156216914, "Ventricular hypertrophy ": 4.085527961301992, "Ventricular tachycardia ": 7.049131529894732, "Weight increased ": 4.012559569934552}
\ No newline at end of file
+{"Haematotoxicity": 900.225238050385, "Mucosal inflammation": 248.2440796808056, "Multiple organ dysfunction syndrome": 40.39871300762043, "Neutropenia": 35.42387814706869, "Pyrexia": 4.059291999752952, "Sepsis": 51.48045479911119}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1230.json
new file mode 100644
index 00000000000..4186516897b
--- /dev/null
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/1230.json
@@ -0,0 +1 @@
+{"5-hydroxyindolacetic acid increased": 14.302888169257942, "Abdominal rebound tenderness": 2.394081166501609, "Abdominal tenderness": 2.067225979275489, "Abdominal wall anomaly": 3.560072764387048, "Abdominal wall haematoma": 4.088024746732292, "Abnormal behaviour": 2.177992589195754, "Abnormal dreams": 2.078897452844542, "Abnormal labour": 4.266278772784978, "Abnormal palmar/plantar creases": 3.9299292077785366, "Abnormal sleep-related event": 2.234926950691295, "Abortion": 2.3717093911966223, "Abortion incomplete": 2.655635127655816, "Abortion induced incomplete": 65.1180162168045, "Abortion threatened": 2.438189529570985, "Abulia": 2.647814235754827, "Accelerated idioventricular rhythm": 4.019963153301754, "Accessory cardiac pathway": 2.212712716221833, "Accidental device ingestion": 8.248223136689962, "Accidental exposure to product": 2.719416208694733, "Accidental exposure to product by child": 5.133496268433132, "Accidental exposure to product packaging": 2.234965918179927, 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acidosis": 2.8606941718904038, "Metabolic alkalosis": 5.488023281268098, "Metabolic encephalopathy": 2.197151916632869, "Metal poisoning": 2.3173684856592693, "Metanephrine urine increased": 4.0041722347359805, "Microcephaly": 4.562332481900437, "Microgenia": 2.091031042875978, "Micrognathia": 4.935728453656419, "Micropenis": 2.1811474582026085, "Microphthalmos": 2.914643786540521, "Microvillous inclusion disease": 3.612151837161976, "Micturition disorder": 2.3804240711935845, "Milk-alkali syndrome": 3.3557558313726283, "Mini mental status examination abnormal": 2.530447090273517, "Miosis": 5.607750137202185, "Mitochondrial encephalomyopathy": 2.0370311496868565, "Mitochondrial enzyme deficiency": 2.846137987720282, "Mitral valve atresia": 2.039075616916378, "Mitral valve sclerosis": 2.217935797520945, "Mitral valve stenosis": 2.1187913171734016, "Mixed liver injury": 2.5739219146976344, "Modified radical mastectomy": 9.520533978993594, "Morbid thoughts": 2.232492002057343, 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2.300029628282558, "Yellow fever": 3.442185040714239, "Yellow fever vaccine-associated neurotropic disease": 28.1021718249388, "Yellow fever vaccine-associated viscerotropic disease": 8.66916440918874}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/124.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/124.json
index f5ed35a56ef..59df58cea7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/124.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/124.json
@@ -1 +1 @@
-{"Cardiotoxicity ": 288.3915723392538, "Disease progression ": 15.402339030639132, "Drug resistance ": 85.13210303001547, "Face oedema ": 43.97098945438533, "Hypersensitivity ": 17.854230528222327, "Multiple-drug resistance ": 221.49405833462865}
\ No newline at end of file
+{"Adrenal insufficiency": 2.547652331140132, "Affective disorder": 5.055907809062501, "Alanine aminotransferase abnormal": 30.97634188610285, "Amyotrophy": 19.553073707509203, "Anaemia": 2.004502510668256, "Anosmia": 7.538387342589545, "Anti-cyclic citrullinated peptide antibody": 23.558599190101067, "Anti-cyclic citrullinated peptide antibody positive": 2.0457074390439764, "Appetite disorder": 6.17778342368496, "Apraxia": 8.26284806705257, "Arthritis": 2.3688772918395093, "Aspirin-exacerbated respiratory disease": 667.0337519371697, "Asthma": 14.69451177993974, "Asthma-chronic obstructive pulmonary disease overlap syndrome": 78.84566730676038, "Asthmatic crisis": 15.095260043360764, "Attention deficit hyperactivity disorder": 2.841887861570987, "Autism spectrum disorder": 3.58904724079506, "Blepharospasm": 10.556652197272408, "Blood alkaline phosphatase abnormal": 101.19851193715763, "Blood immunoglobulin E increased": 20.237408652798564, "Blood insulin abnormal": 94.81407601380678, 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abnormal": 21.705037768862503, "Pulmonary mass": 7.129125920356038, "Radiculopathy": 63.86569190091807, "Rectal haemorrhage": 10.580093144170958, "Respiratory gas exchange disorder": 64.98299537735419, "Respiratory symptom": 4.034955638732342, "Respiratory tract infection": 16.880285945499573, "Respiratory tract inflammation": 27.92944448162877, "Restrictive pulmonary disease": 20.29497736654046, "Reversible airways obstruction": 94.12050615838189, "Rhinalgia": 25.89613634342738, "Rhinitis": 4.125751884008887, "Rhinitis allergic": 20.081912436125357, "Rhinorrhoea": 11.876380358729463, "Sarcoidosis": 8.407703734351733, "Seasonal allergy": 9.666191985819763, "Secretion discharge": 63.03697584766921, "Sensory processing disorder": 57.02021714806973, "Sinus congestion": 9.955669215619595, "Sinus headache": 2.7924895014483506, "Sinusitis": 9.97472832818264, "Sleep apnoea syndrome": 17.27742857981414, "Sleep disorder due to a general medical condition": 46.21453076288804, "Sneezing": 6.809258122185249, "Social avoidant behaviour": 3.2149051771407864, "Sputum discoloured": 30.475380767345754, "Stent placement": 11.590201927682855, "Stereotypy": 12.708036874652258, "Taste disorder": 2.9775636617245675, "Therapeutic product effect incomplete": 28.04839728663804, "Therapy interrupted": 2.3063966025923097, "Throat clearing": 205.74646166751603, "Throat irritation": 3.262700337681529, "Thyroid cancer": 2.525794753697124, "Thyroid disorder": 4.256288605575644, "Thyroid neoplasm": 13.722803177905666, "Thyroidectomy": 12.096223340649193, "Tooth development disorder": 70.67433554606883, "Total lung capacity decreased": 12.095119837781771, "Total lung capacity increased": 223.48572307956488, "Tracheomalacia": 46.54538184559989, "Upper respiratory tract infection": 3.048495005724205, "Upper-airway cough syndrome": 9.218662330021168, "Vaginal discharge": 45.6489737456856, "Vaginal flatulence": 103.03481513515058, "Vital capacity decreased": 33.687069435232296, "Weight decreased": 2.75189376095752, "Wheezing": 16.31008188742783}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/125.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/125.json
index b54165d7247..bd5cd8f2815 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/125.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/125.json
@@ -1 +1 @@
-{"Abdominal abscess ": 9.172792028809967, "Abdominal pain lower ": 2.0875308007656788, "Abscess ": 2.725261632807709, "Acute myeloid leukaemia ": 3.104121818912148, "Anaemia ": 2.283798329725504, "Anal fistula ": 14.96573745781695, "Anaphylactoid reaction ": 5.713601580506567, "Aortic dissection ": 7.369900695043835, "Ascites ": 3.7675203174012375, "Astrocytoma ": 32.01138660729955, "Blindness ": 2.172725269532234, "Blindness transient ": 2.874154525701481, "Blindness unilateral ": 3.184626907555024, "Brain oedema ": 3.706183331683051, "Breast cancer metastatic ": 2.0348898292989803, "Cachexia ": 2.748447505008456, "Carbohydrate antigen 125 increased ": 10.372302789020672, "Carcinoembryonic antigen increased ": 18.898545224348137, "Cardiac failure ": 2.738780887016666, "Cardiomyopathy ": 2.681714525286883, "Cardiotoxicity ": 2.460869654027173, "Cerebral haemorrhage ": 2.296034218601947, "Cerebral infarction ": 3.999783308337639, "Cerebral ischaemia ": 3.78920540299282, "Cholecystitis acute ": 3.767793974396821, "Cholestasis ": 2.1616983788964, "Colitis ischaemic ": 3.261794753444086, "Colon cancer ": 4.297730030012303, "Colon cancer metastatic ": 45.76264673786483, "Colorectal cancer metastatic ": 35.99606509494143, "Constipation ": 2.2389320076574117, "Cytopenia ": 2.9195586738534662, "Decreased appetite ": 2.619136987014389, "Deep vein thrombosis ": 3.380159359957968, "Dehydration ": 2.584103758227644, "Dermatitis acneiform ": 3.6640948258434687, "Detachment of retinal pigment epithelium ": 18.024381748471328, "Device related infection ": 4.940960810797854, "Device related thrombosis ": 19.51913886594531, "Diarrhoea ": 2.6271439529554184, "Disease progression ": 28.22371270782651, "Disseminated intravascular coagulation ": 8.82674543453865, "Diverticular perforation ": 8.203165485461634, "Duodenal perforation ": 34.62008105327172, "Duodenal ulcer ": 3.3403461977729365, "Duodenal ulcer haemorrhage ": 5.8394109725486905, "Dyslalia ": 8.456253274498467, "Ejection fraction decreased ": 4.054034430740322, "Embolism ": 5.611722486720088, "Embolism venous ": 12.98147081650123, "Endophthalmitis ": 4.775386871321967, "Enteritis ": 4.352757073786924, "Enterocolitis ": 5.799014917436428, "Enterocutaneous fistula ": 67.85565016741296, "Epistaxis ": 3.32755121769311, "Eye inflammation ": 2.4011158012173035, "Faeces soft ": 4.149022194990533, "Febrile neutropenia ": 6.021737715764351, "Female genital tract fistula ": 6.288492714169968, "Fistula ": 14.77510698005488, "Fournier's gangrene ": 4.595623332618251, "Gastric haemorrhage ": 2.5488917458702662, "Gastric perforation ": 30.30503464692183, "Gastric ulcer ": 5.4807383798835305, "Gastric ulcer haemorrhage ": 3.934102210524969, "Gastrointestinal necrosis ": 10.786525829714742, "Gastrointestinal perforation ": 94.09625524929132, "Gastrointestinal toxicity ": 12.099988537573765, "Granulocyte count decreased ": 12.49142713088438, "Haematotoxicity ": 6.31299408667928, "Haemoglobin decreased ": 2.0647602947791115, "Haemolytic anaemia ": 2.031984668188326, "Haemolytic uraemic syndrome ": 4.578669634867675, "Haemoptysis ": 2.7342387105537305, "Hepatic atrophy ": 42.75373858081608, "Hepatic lesion ": 3.229967050805918, "Hepatic steatosis ": 2.39125510912377, "Hiccups ": 4.821485675719646, "Hydronephrosis ": 6.009359386455053, "Hyperammonaemia ": 12.723817571509231, "Hypertension ": 3.5082801243620265, "Hypoalbuminaemia ": 3.626102605887076, "Hypomagnesaemia ": 3.229284732308967, "Ileal perforation ": 97.7315004757852, "Ileus ": 10.860033995943873, "Impaired healing ": 3.2957296428401337, "Intentional product use issue ": 2.577616702989084, "Interstitial lung disease ": 8.255300122299978, "Intestinal ischaemia ": 2.9830168985159258, "Intestinal obstruction ": 8.377826869129965, "Intestinal perforation ": 21.112829183175705, "Invasive ductal breast carcinoma ": 2.5057372965375158, "Jugular vein thrombosis ": 9.749576248004312, "KL-6 increased ": 12.268590074793543, "Large intestine perforation ": 43.322128058452186, "Left ventricular dysfunction ": 3.7269477565575433, "Leukoencephalopathy ": 8.278959534084095, "Leukopenia ": 2.7890573125360465, "Liver abscess ": 5.37008012130089, "Lymphangiosis carcinomatosa ": 16.17035983169931, "Macular oedema ": 5.276359869718402, "Malignant neoplasm progression ": 4.947617691044979, "Melaena ": 2.069628089556249, "Metastases to bone ": 4.2378201426009, "Metastases to central nervous system ": 5.874240879541268, "Metastases to liver ": 7.939289503185602, "Metastases to lung ": 9.557683838820886, "Metastases to lymph nodes ": 6.847831531591747, "Metastases to pelvis ": 19.490208918049344, "Metastases to peritoneum ": 8.460768537383478, "Metastasis ": 5.908860087813162, "Metastatic neoplasm ": 5.685191986693974, "Mucosal disorder ": 3.602166329713131, "Mucosal inflammation ": 5.809776800295488, "Myelosuppression ": 9.426161035139668, "Myocardial ischaemia ": 2.7856789725911706, "Necrotising fasciitis ": 14.715574417008808, "Neoplasm ": 3.672894875103706, "Neoplasm progression ": 4.704938817888281, "Nephrotic syndrome ": 6.427338098305752, "Neuropathy peripheral ": 12.081827812302471, "Neurotoxicity ": 11.859621701008011, "Neutropenia ": 6.732960282702266, "Neutropenic sepsis ": 3.358737286018038, "Neutrophil count decreased ": 15.289174838907774, "Neutrophilia ": 5.001843633647941, "Oesophageal varices haemorrhage ": 7.760295211814483, "Osteonecrosis of jaw ": 5.62825923534458, "Ovarian cancer ": 4.4598789094008495, "Palmar-plantar erythrodysaesthesia syndrome ": 8.293684266110146, "Paronychia ": 4.377019549516368, "Peripheral sensory neuropathy ": 10.619619192454635, "Peritoneal disorder ": 52.850759373403775, "Peritonitis ": 23.90244897684604, "Pigmentation disorder ": 3.009323132020194, "Platelet count decreased ": 4.61056391993668, "Pneumatosis intestinalis ": 6.979874937005742, "Polyneuropathy ": 2.167719653710725, "Portal hypertension ": 11.640929385326508, "Portal vein thrombosis ": 7.608930707820455, "Posterior reversible encephalopathy syndrome ": 8.302118346397739, "Proctalgia ": 2.5874098425158985, "Protein urine ": 26.45948413838928, "Protein urine present ": 7.267891011873724, "Proteinuria ": 14.67991337313445, "Pulmonary artery thrombosis ": 20.34702691297952, "Pulmonary embolism ": 4.438492024092371, "Pulmonary haemorrhage ": 2.3209362428387066, "Rectal cancer ": 8.746797235302799, "Rectal cancer metastatic ": 51.48815223798599, "Rectal haemorrhage ": 4.698186352390009, "Rectal perforation ": 183.126423917505, "Red cell distribution width increased ": 3.812224159576691, "Retinal artery occlusion ": 3.3459176383378346, "Retinal haemorrhage ": 2.7356853705294304, "Retinal oedema ": 10.193139501189185, "Retinal vascular occlusion ": 9.221081610538429, "Sepsis ": 2.6183742526814937, "Septic shock ": 2.023682539787245, "Shock ": 3.069680801595763, "Shock haemorrhagic ": 2.363712040246158, "Skin toxicity ": 3.58210425107559, "Small intestinal obstruction ": 3.1253407510019136, "Small intestinal perforation ": 44.311739542033294, "Splenomegaly ": 2.796556488944058, "Stoma site haemorrhage ": 53.2552137640838, "Stomatitis ": 5.90089126977439, "Subileus ": 17.90211670381095, "Subretinal fluid ": 13.88802282469683, "Therapy partial responder ": 5.44805667250569, "Thrombocytopenia ": 3.3998015848393264, "Thrombophlebitis ": 2.4654395695842592, "Thrombotic microangiopathy ": 2.627833428447544, "Thrombotic thrombocytopenic purpura ": 3.469261436832653, "Tumour haemorrhage ": 17.69082901016076, "Tumour lysis syndrome ": 2.1553987684089586, "Tumour marker increased ": 5.24900191594458, "Tumour necrosis ": 21.54500577577872, "Tumour perforation ": 106.34188424390754, "Ulcer ": 2.041510679289038, "Varices oesophageal ": 11.179811456468952, "Vascular device infection ": 3.489753644191182, "Vena cava thrombosis ": 13.893190156877472, "Venoocclusive liver disease ": 2.771774006924689, "Venous thrombosis ": 10.272739588740585, "Venous thrombosis limb ": 6.516523192323351, "Ventricular hypertrophy ": 8.9608551125142, "Visual acuity reduced ": 3.7106504056524, "Vitreous detachment ": 6.367057047321531, "Vitreous floaters ": 4.067409674789608, "Vitritis ": 3.25714043731804, "White blood cell count decreased ": 6.900969549396407, "Wound dehiscence ": 15.963747807507271, "Wound infection ": 7.606822867032728}
\ No newline at end of file
+{"Acute coronary syndrome": 60.71043296661498, "Acute myocardial infarction": 23.618047233122965, "Acute pulmonary oedema": 5.511566529707905, "Amnesia": 2.891006817442729, "Angina pectoris": 12.503593489808305, "Angina unstable": 100.22710915779828, "Angioplasty": 45.84325643231059, "Aortic stenosis": 10.85419364374887, "Arrhythmia": 2.763557013166295, "Arterial occlusive disease": 18.58232363788637, "Arteriosclerosis": 44.49856676448125, "Arteriosclerosis coronary artery": 51.45619721533965, "Atrial fibrillation": 10.24163070631221, "Atrial flutter": 11.752151480888234, "Atrioventricular block": 4.80374648200177, "Atrioventricular block complete": 7.415844798664104, "Blindness": 4.482629514624176, "Cardiac arrest": 5.140590329875609, "Cardiac disorder": 28.943638573777896, "Cardiac failure": 3.7884607402314256, "Cardiac failure congestive": 104.45365419160404, "Cardiac operation": 14.58077631782412, "Cardiac pacemaker insertion": 19.937834517446312, "Cardiac valve disease": 11.853169181862691, "Cardiac ventricular thrombosis": 11.341652948128472, "Cardio-respiratory arrest": 3.392282987161156, "Cardiogenic shock": 5.5947484536308805, "Cardiomegaly": 11.894069204386057, "Cardiomyopathy": 33.29832491463044, "Cardiovascular disorder": 34.3377536578613, "Carotid artery disease": 34.88417120150129, "Catheterisation cardiac": 21.67903078095096, "Cerebral infarction": 2.357329880691526, "Cerebrovascular accident": 22.68274715899781, "Cerebrovascular disorder": 21.709715064212386, "Chest pain": 2.9880563191681166, "Chronic obstructive pulmonary disease": 2.151260034691944, "Coronary arterial stent insertion": 55.372997306132895, "Coronary artery bypass": 116.1391656005156, "Coronary artery disease": 169.08569785564652, "Coronary artery occlusion": 16.115326487772382, "Coronary artery stenosis": 8.483288827221196, "Diabetic retinopathy": 6.479268986983397, "Dilated cardiomyopathy": 21.715518874769412, "Fluid retention": 4.868525016089837, "Heart rate irregular": 5.271241572513962, "Hemiparesis": 3.016614290586319, "Hemiplegia": 2.893038001513855, "Hyperlipidaemia": 15.304757636588963, "Hypertension": 2.128154993026073, "Hypertensive heart disease": 27.68616959106914, "Implantable defibrillator insertion": 72.10628156499364, "Injury": 6.081850633851287, "Ischaemia": 10.738798988022532, "Ischaemic cardiomyopathy": 169.05160863372032, "Ischaemic stroke": 2.4155015201814027, "Lacunar infarction": 11.344734333160911, "Left ventricular dysfunction": 5.097039210258387, "Macular oedema": 26.75152210463802, "Mitral valve incompetence": 8.707804642688046, "Myocardial infarction": 63.61789877734254, "Myocardial injury": 147.73120757729404, "Myocardial ischaemia": 105.0980192728626, "Oedema": 2.3627474756270748, "Pericardial effusion": 3.9064900829692415, "Peripheral vascular disorder": 5.234960823364357, "Pleural effusion": 5.8238861351108175, "Pulmonary hypertension": 4.95285884304413, "Pulmonary oedema": 7.573494377602544, "Silent myocardial infarction": 133.53069705627797, "Sinus node dysfunction": 23.844714122606327, "Stent placement": 73.18778338968191, "Sudden cardiac death": 12.478341212113836, "Supraventricular tachycardia": 9.139617413033282, "Transient ischaemic attack": 23.62075395691535, "Ventricular fibrillation": 4.765279158410529, "Ventricular tachycardia": 7.567434640734304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/126.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/126.json
index 5c142074963..f6e062fcf02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/126.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/126.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 3.945711070899304, "Aphthous ulcer ": 8.374486553079608, "Arthritis ": 4.3810188036593765, "Aspartate aminotransferase increased ": 2.667095024285793, "Death ": 2.099160638053909, "Dehydration ": 2.1440375839233727, "Diarrhoea ": 4.0359957295032665, "Disease progression ": 24.667426889164616, "Dysphonia ": 12.464257655064747, "Febrile neutropenia ": 7.9766715281757135, "General physical health deterioration ": 3.742244031194057, "Haematuria ": 2.679155157518853, "Hepatitis ": 5.186145496372268, "Hypertension ": 6.896219057994264, "Hyperthyroidism ": 17.66081019452021, "Hypertransaminasaemia ": 12.68088634569746, "Hypokalaemia ": 2.020972390119396, "Hypothyroidism ": 30.30551508517025, "Immune-mediated hepatitis ": 55.05827703969306, "Infusion related reaction ": 16.322856595610713, "Mucosal inflammation ": 11.506867451942869, "Myocarditis ": 6.266588365811183, "Myositis ": 14.199936351905746, "Neoplasm progression ": 34.31551260473867, "Off label use ": 4.255352582443684, "Palmar-plantar erythrodysaesthesia syndrome ": 4.649060618661651, "Pneumonitis ": 8.365874232351949, "Stomatitis ": 2.1646869755117897, "Transaminases increased ": 2.92623304726028}
\ No newline at end of file
+{"Acute coronary syndrome": 38.27116578786335, "Acute myocardial infarction": 21.50512379412397, "Acute pulmonary oedema": 6.5843825648219205, "Acute respiratory failure": 2.3903323532447263, "Alanine aminotransferase increased": 2.0078399660957147, "Amnesia": 2.463285906066578, "Aneurysm": 3.6539815259801465, "Angina pectoris": 10.07954079592127, "Angina unstable": 77.83761588051956, "Angiopathy": 4.333558304004541, "Angioplasty": 25.75840700252757, "Aortic aneurysm": 2.5261139334429763, "Aortic arteriosclerosis": 5.367409323557069, "Aortic stenosis": 17.233442658468967, "Aortic valve disease": 7.269905223714561, "Aortic valve incompetence": 4.580170668540155, "Aortic valve replacement": 18.602610553937968, "Aortic valve stenosis": 10.39883154122372, "Arrhythmia": 3.3864220168075776, "Arterial disorder": 7.327198674532172, "Arterial occlusive disease": 12.997503544288795, "Arterial stenosis": 6.678563257384186, "Arteriosclerosis": 29.9932414377477, "Arteriosclerosis coronary artery": 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"Ischaemic cardiomyopathy": 234.05620985013016, "Ischaemic stroke": 3.742709476090834, "Jugular vein distension": 9.058979089733969, "Lacunar infarction": 16.58420049389253, "Left atrial enlargement": 11.297753703386013, "Left ventricular dysfunction": 6.683133943722663, "Left ventricular failure": 6.345851504312924, "Left ventricular hypertrophy": 7.09938559562857, "Leg amputation": 4.68164557239068, "Macular oedema": 50.570604294264726, "Mitral valve disease": 15.396607845184848, "Mitral valve incompetence": 9.88420787721383, "Mitral valve prolapse": 5.6126197414567605, "Myocardial infarction": 65.88708404164942, "Myocardial injury": 181.7509825862903, "Myocardial ischaemia": 75.73261401072858, "Obstruction": 7.250883023933782, "Oedema": 5.649473610403978, "Oedema peripheral": 3.074916583239504, "Orthopnoea": 11.616204282460613, "Oxygen therapy": 8.30495392094646, "Percutaneous coronary intervention": 30.486712478463133, "Pericardial effusion": 5.3884355503676105, "Peripheral arterial occlusive disease": 3.595742729762115, "Peripheral vascular disorder": 6.756682927408639, "Pleural effusion": 7.119391126015489, "Pulmonary hypertension": 7.998518804061009, "Pulmonary oedema": 10.48716253994342, "Renal artery stenosis": 3.5803294054449943, "Renal failure": 2.0501693966716874, "Respiratory failure": 3.0817669396131757, "Silent myocardial infarction": 101.08552263729445, "Sinus node dysfunction": 22.91092917009161, "Stent placement": 76.16923964738442, "Sudden cardiac death": 16.255661799610106, "Supraventricular tachycardia": 7.62513411611777, "Systolic dysfunction": 4.647644783279799, "Toe amputation": 2.205213782983147, "Transient ischaemic attack": 22.866042068495744, "Traumatic lung injury": 5.651198721492126, "Tricuspid valve incompetence": 4.319504011342207, "Vascular graft": 48.133238740483016, "Vascular occlusion": 2.842262095458905, "Ventricular arrhythmia": 4.790327141951398, "Ventricular fibrillation": 6.730305156216914, "Ventricular hypertrophy": 4.085527961301992, "Ventricular tachycardia": 7.049131529894732, "Weight increased": 4.012559569934552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/127.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/127.json
index a97c7fc988b..a752e25f330 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/127.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/127.json
@@ -1 +1 @@
-{"Adverse drug reaction ": 5.846551572097564, "Breast cancer ": 3.217422058519721, "Carpal tunnel syndrome ": 18.056008123809608, "Chronic kidney disease ": 3.082942409234644, "Congenital aortic anomaly ": 717.2370049754162, "Depression ": 3.461567957069028, "Diabetic neuropathy ": 38.56803408252614, "Encephalitis autoimmune ": 80.16806606228965, "Exposure during pregnancy ": 2.0113939867838555, "Fall ": 2.2505888632388173, "Fibromyalgia ": 6.382653422141187, "Gait disturbance ": 3.953901283039694, "Haemorrhoids ": 8.808383760899382, "Hyperlipidaemia ": 14.811015150856756, "Hypothyroidism ": 3.589389630015726, "Illness ": 2.199414154102292, "Implant site swelling ": 765.3409833463292, "Influenza like illness ": 2.308208306179784, "Intrathecal pump insertion ": 2860.8734320198582, "Medical device removal ": 612.9718071700232, "Medical device site infection ": 1110.911552596269, "Memory impairment ": 3.118720419413033, "Mitral valve prolapse ": 138.07514204204986, "Multiple sclerosis ": 55.70613096320757, "Multiple sclerosis relapse ": 52.38570504027653, "Muscle spasticity ": 47.86737051065053, "Muscular weakness ": 2.556692857144089, "Neuropathy peripheral ": 5.331845499672351, "Osteoarthritis ": 5.473311161671718, "Pancreatitis ": 2.7493343494663707, "Peptic ulcer ": 55.63652702114012, "Psoriasis ": 3.651217352739838, "Rhabdomyolysis ": 3.440910591764494, "Sleep apnoea syndrome ": 19.10013005312653, "Staphylococcal infection ": 23.59299833629277, "Stress ": 5.874309791535641, "Therapy non-responder ": 6.185364191619148, "Urinary tract infection ": 2.528806725828647}
\ No newline at end of file
+{"Cardiotoxicity": 288.3915723392538, "Disease progression": 15.402339030639132, "Drug resistance": 85.13210303001547, "Face oedema": 43.97098945438533, "Hypersensitivity": 17.854230528222327, "Multiple-drug resistance": 221.49405833462865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/128.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/128.json
index 6bdf179e0cf..eb98623cdbe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/128.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/128.json
@@ -1 +1 @@
-{"Bronchopulmonary aspergillosis ": 37.950786354948434, "Cardiac tamponade ": 47.35308898612319, "Cellulitis ": 6.827100509368127, "Cytokine release syndrome ": 532.035408602709, "Cytokine storm ": 207.16301814372397, "Cytopenia ": 23.79181085440169, "Diffuse large B-cell lymphoma ": 56.71476246147901, "Disease progression ": 15.504676526452686, "Encephalopathy ": 20.69605486978968, "Febrile neutropenia ": 7.587044907758247, "Hypogammaglobulinaemia ": 81.93672085599854, "Immune effector cell-associated neurotoxicity syndrome ": 701.3511367824474, "Infection reactivation ": 230.9584636332921, "Myelodysplastic syndrome ": 21.785252719774228, "Myelosuppression ": 4.29364959033556, "Neurotoxicity ": 96.237660765208, "Neutropenia ": 7.847349187259715, "Neutrophil count decreased ": 3.941681416305357, "Off label use ": 2.2465520397093868, "Pancytopenia ": 7.408489041631926, "Platelet count decreased ": 2.123433829948547, "Septic shock ": 8.30347078718364, "Thrombocytopenia ": 4.764848267732937, "Tumour lysis syndrome ": 55.43007643811781, "White blood cell count decreased ": 2.602999876440353}
\ No newline at end of file
+{"Abdominal abscess": 9.114955028457958, "Abdominal pain lower": 2.074367710277325, "Abscess": 2.7080778920550657, "Acute myeloid leukaemia": 3.084548536380254, "Anaemia": 2.269392455913363, "Anal fistula": 14.871372989625067, "Anaphylactoid reaction": 5.677572293275682, "Aortic dissection": 7.323431601678797, "Ascites": 3.743761523494976, "Astrocytoma": 31.809550802982965, "Blindness": 2.159024193576497, "Blindness transient": 2.856032098484932, "Blindness unilateral": 3.1645462352911022, "Brain oedema": 3.682813638203828, "Breast cancer metastatic": 2.022059222445583, "Cachexia": 2.731118142576121, "Carbohydrate antigen 125 increased": 10.30690396363387, "Carcinoembryonic antigen increased": 18.77938066823662, "Cardiac failure": 2.721258828054646, "Cardiomyopathy": 2.664804813306348, "Cardiotoxicity": 2.4453535113826077, "Cerebral haemorrhage": 2.281554901741985, "Cerebral infarction": 3.974559677655221, "Cerebral ischaemia": 3.7653134912833535, "Cholecystitis acute": 3.744037375387608, "Cholestasis": 2.1480673925945566, "Colitis ischaemic": 3.4958110430580147, "Colon cancer": 4.270630284671753, "Colon cancer metastatic": 45.47408539876791, "Colorectal cancer metastatic": 35.76908767513393, "Constipation": 2.2248108438797547, "Cytopenia": 2.898834946093108, "Decreased appetite": 2.6101978123405, "Deep vein thrombosis": 3.4354627037165035, "Dehydration": 2.5676687532126734, "Dermatitis acneiform": 3.6409918643243473, "Detachment of retinal pigment epithelium": 17.910735588289313, "Device related infection": 4.909805676757961, "Device related thrombosis": 19.396066960536587, "Diarrhoea": 2.6205453465232944, "Disease progression": 28.045569615282854, "Disseminated intravascular coagulation": 8.771080770301095, "Diverticular perforation": 8.151443121089354, "Duodenal perforation": 34.40179005138358, "Duodenal ulcer": 3.3192842900964306, "Duodenal ulcer haemorrhage": 5.802591850002765, "Dyslalia": 8.402934911015592, "Ejection fraction decreased": 4.028470912312301, "Embolism": 5.576337448926301, "Embolism venous": 12.899617571292591, "Endophthalmitis": 4.7452756653108565, "Enteritis": 4.325311608423399, "Enterocolitis": 5.7624495807111416, "Enterocutaneous fistula": 67.42780119024435, "Epistaxis": 3.3649741178406183, "Eye inflammation": 2.3859760867463984, "Faeces soft": 4.122861547296017, "Febrile neutropenia": 5.983756346775339, "Female genital tract fistula": 6.248840626523406, "Fistula": 14.681941022262109, "Fournier's gangrene": 4.566646751941444, "Gastric haemorrhage": 2.532820138738656, "Gastric perforation": 30.11394410185521, "Gastric ulcer": 5.442533151186426, "Gastric ulcer haemorrhage": 3.909296305289317, "Gastrointestinal necrosis": 10.718512787954406, "Gastrointestinal perforation": 93.50277957307928, "Gastrointestinal toxicity": 12.023691216921158, "Granulocyte count decreased": 12.41265986128413, "Haematotoxicity": 6.273187028564526, "Haemoglobin decreased": 2.051738689249601, "Haemolytic anaemia": 2.0191721922886, "Haemolytic uraemic syndrome": 4.549800460976415, "Haemoptysis": 2.716996919642155, "Hepatic atrophy": 42.48416653659967, "Hepatic lesion": 3.20960163852152, "Hepatic steatosis": 2.3761769506473835, "Hiccups": 4.791083889350189, "Hydronephrosis": 5.97146761264325, "Hyperammonaemia": 12.64358140586052, "Hypertension": 3.518760775975482, "Hypoalbuminaemia": 3.6032389172083135, "Hypomagnesaemia": 3.208922875381354, "Ileal perforation": 97.11525318232968, "Ileus": 10.791549952735384, "Impaired healing": 3.2749468826524013, "Intentional product use issue": 2.5613615753747645, "Interstitial lung disease": 8.203222251126874, "Intestinal ischaemia": 2.964208542346468, "Intestinal obstruction": 8.3249934220319, "Intestinal perforation": 20.97968392431629, "Invasive ductal breast carcinoma": 2.489938334353353, "Jugular vein thrombosis": 9.688102969826112, "KL-6 increased": 12.191234908350284, "Large intestine perforation": 43.0489168396272, "Left ventricular dysfunction": 3.703448119448539, "Leukoencephalopathy": 8.226757427218484, "Leukopenia": 2.771116943499772, "Liver abscess": 5.3362209929513895, "Lymphangiosis carcinomatosa": 16.068402141762757, "Macular oedema": 5.243090939831142, "Malignant neoplasm progression": 4.916407068228724, "Melaena": 2.05631143636761, "Metastases to bone": 4.211097455902413, "Metastases to central nervous system": 5.837199414939609, "Metastases to liver": 7.889221364724828, "Metastases to lung": 9.497411210528316, "Metastases to lymph nodes": 6.804651773448049, "Metastases to pelvis": 19.367320539680247, "Metastases to peritoneum": 8.407420830235772, "Metastasis": 5.871602254095089, "Metastatic neoplasm": 5.649345866355414, "Mucosal disorder": 3.579454259021772, "Mucosal inflammation": 5.773138398928983, "Myelosuppression": 9.366692136196528, "Myocardial ischaemia": 2.7681140943468563, "Necrotising fasciitis": 14.622785480322582, "Neoplasm": 3.64973605911209, "Neoplasm progression": 4.675266832018198, "Nephrotic syndrome": 6.386808746670626, "Neuropathy peripheral": 12.005233180159395, "Neurotoxicity": 11.784830169993056, "Neutropenia": 6.69018887965792, "Neutropenic sepsis": 3.3375598598567167, "Neutrophil count decreased": 15.192716077443364, "Neutrophilia": 4.970306288047714, "Oesophageal varices haemorrhage": 7.711364584317572, "Osteonecrosis of jaw": 5.592769820614654, "Ovarian cancer": 4.4317581182727, "Palmar-plantar erythrodysaesthesia syndrome": 8.24137452389772, "Paronychia": 4.349421678818835, "Peripheral sensory neuropathy": 10.552654803100868, "Peritoneal disorder": 52.517525052916696, "Peritonitis": 23.75170365490472, "Pigmentation disorder": 2.990348576193296, "Platelet count decreased": 4.58148089002947, "Pneumatosis intestinalis": 6.935865425759129, "Polyneuropathy": 2.154051222114548, "Portal hypertension": 11.56752803062478, "Portal vein thrombosis": 7.56095306879073, "Posterior reversible encephalopathy syndrome": 8.249766445771781, "Proctalgia": 2.571095925674812, "Protein urine": 26.29264882483542, "Protein urine present": 7.222063625544352, "Proteinuria": 14.587322598909042, "Pulmonary artery thrombosis": 22.27213658821236, "Pulmonary embolism": 4.483784087047567, "Pulmonary haemorrhage": 2.306302203067307, "Rectal cancer": 8.654258959954422, "Rectal cancer metastatic": 51.1635121695772, "Rectal haemorrhage": 4.668556507379652, "Rectal perforation": 181.97170946830076, "Red cell distribution width increased": 3.7881876508101664, "Retinal artery occlusion": 3.3248211410057165, "Retinal haemorrhage": 2.7184359044385493, "Retinal oedema": 10.128870024310418, "Retinal vascular occlusion": 9.162941672827689, "Sepsis": 2.60186101021072, "Septic shock": 2.010921705790464, "Shock": 3.0503238418718728, "Shock haemorrhagic": 2.3488080521691344, "Skin toxicity": 3.5544058480220126, "Small intestinal obstruction": 3.105634841817754, "Small intestinal perforation": 44.03232481266284, "Splenomegaly": 2.778922906628784, "Stoma site haemorrhage": 52.91942055047259, "Stomatitis": 5.86367331622579, "Subileus": 17.789236553268882, "Subretinal fluid": 13.800457352485596, "Therapy partial responder": 5.4137034391108765, "Thrombocytopenia": 3.378035901214802, "Thrombophlebitis": 2.836003770832646, "Thrombotic microangiopathy": 2.611264195661572, "Thrombotic thrombocytopenic purpura": 3.4473869441765035, "Tumour haemorrhage": 17.57927710369939, "Tumour lysis syndrome": 2.141808539161988, "Tumour marker increased": 5.215905485521831, "Tumour necrosis": 21.409158737716627, "Tumour perforation": 105.67136921006804, "Ulcer": 2.0286384818830143, "Varices oesophageal": 11.109318120336772, "Vascular device infection": 3.4677502402851026, "Vena cava thrombosis": 13.805590137880264, "Venoocclusive liver disease": 2.754297485724328, "Venous thrombosis": 10.207961573406449, "Venous thrombosis limb": 6.475433388889466, "Ventricular hypertrophy": 8.904355929974143, "Visual acuity reduced": 3.6872517529573248, "Vitreous detachment": 6.326911472866099, "Vitreous floaters": 4.041762779810134, "Vitritis": 3.236603692941248, "White blood cell count decreased": 6.857434178679004, "Wound dehiscence": 15.863090890130284, "Wound infection": 7.558858208689822}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/129.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/129.json
index 86d5c5982bf..0c8ca60b539 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/129.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/129.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 11.393833915921212, "Adverse event ": 2.3414006515089265, "Alanine aminotransferase increased ": 5.38940663197809, "Aphthous ulcer ": 3.3673544198793226, "Aspartate aminotransferase increased ": 4.500276336044569, "Blood bilirubin increased ": 2.821920756991148, "Blood pressure increased ": 2.2695254341026607, "Blood thyroid stimulating hormone increased ": 11.253398831694664, "Cardiac dysfunction ": 17.498413234950416, "Colitis ": 3.2702718949425544, "Decreased appetite ": 2.9149107005178125, "Dehydration ": 2.3972255478731626, "Diarrhoea ": 4.926284280621987, "Disease progression ": 7.010664653476092, "Drug-induced liver injury ": 4.034734183319895, "Dysphonia ": 13.71902139933939, "Encephalitis ": 6.397276805396016, "General physical health deterioration ": 2.698083704506822, "Hepatic function abnormal ": 4.788479524448436, "Hepatitis ": 16.758122107128052, "Hepatotoxicity ": 14.272362363384111, "Hypertension ": 8.907816677691093, "Hyperthyroidism ": 6.025984053788545, "Hypertransaminasaemia ": 12.064396994877864, "Hypophagia ": 3.744226475444639, "Hypophysitis ": 17.305085328067893, "Hypopituitarism ": 34.941480539154895, "Hypothyroidism ": 27.577781786180037, "Immune-mediated adrenal insufficiency ": 31.67364996594425, "Immune-mediated enterocolitis ": 13.01830059839609, "Immune-mediated hepatic disorder ": 87.1198856764298, "Immune-mediated hepatitis ": 26.97754940870548, "Immune-mediated hyperthyroidism ": 56.16742196589801, "Immune-mediated hypothyroidism ": 75.94154727669668, "Immune-mediated myocarditis ": 46.68329156981822, "Liver disorder ": 3.3729178115512246, "Liver function test increased ": 4.287770032955797, "Liver injury ": 2.7818436503589345, "Malignant neoplasm progression ": 19.186621125061976, "Metastases to lung ": 8.412810015504931, "Metastatic renal cell carcinoma ": 15.124255365368272, "Mucosal inflammation ": 10.235257851890683, "Myasthenia gravis ": 12.11973995023847, "Myocarditis ": 2.96007335532532, "Myositis ": 9.919810495913202, "Neoplasm progression ": 23.478976029793955, "Nephritis ": 17.292789469821198, "Off label use ": 2.499145924108316, "Osteonecrosis of jaw ": 10.442535568322572, "Palmar-plantar erythrodysaesthesia syndrome ": 21.53643371209697, "Pancreatitis acute ": 2.2003738649165308, "Pneumonitis ": 5.801531428388537, "Polycythaemia ": 41.579890874547424, "Posterior reversible encephalopathy syndrome ": 15.43629919383513, "Product use in unapproved indication ": 2.499799584092084, "Proteinuria ": 10.719986954240738, "Pulmonary mass ": 3.930864957697491, "Renal cell carcinoma ": 7.949600331180702, "Skin disorder ": 2.0561812031397326, "Skin reaction ": 2.818047522677273, "Stomatitis ": 5.030058807297966, "Therapy partial responder ": 35.51013363548202, "Thyroid disorder ": 4.205265780274622, "Thyroiditis ": 18.15431951042947, "Transaminases increased ": 6.058471708250701, "Tubulointerstitial nephritis ": 6.647886705238142, "Type 1 diabetes mellitus ": 5.437023362398193, "Weight decreased ": 2.693083637418138}
\ No newline at end of file
+{"Alanine aminotransferase increased": 3.945711070899304, "Aphthous ulcer": 8.374486553079608, "Arthritis": 4.3810188036593765, "Aspartate aminotransferase increased": 2.667095024285793, "Death": 2.099160638053909, "Dehydration": 2.1439231431049697, "Diarrhoea": 4.035962034485856, "Disease progression": 24.667426889164616, "Dysphonia": 12.464257655064747, "Febrile neutropenia": 7.9766715281757135, "General physical health deterioration": 3.742244031194057, "Haematuria": 2.679155157518853, "Hepatitis": 5.186145496372268, "Hypertension": 6.896147817203588, "Hyperthyroidism": 17.65920078636035, "Hypertransaminasaemia": 12.68088634569746, "Hypokalaemia": 2.020972390119396, "Hypothyroidism": 30.30551508517025, "Immune-mediated hepatitis": 55.05827703969306, "Infusion related reaction": 16.322856595610713, "Mucosal inflammation": 11.506867451942869, "Myocarditis": 6.266588365811183, "Myositis": 14.199936351905746, "Neoplasm progression": 34.31551260473867, "Off label use": 4.255184912259202, "Palmar-plantar erythrodysaesthesia syndrome": 4.649060618661651, "Pneumonitis": 8.365874232351949, "Stomatitis": 2.1646869755117897, "Transaminases increased": 2.926053865679717}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/13.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/13.json
index d67cd1c5c01..dff7e1e6fe7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/13.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/13.json
@@ -1 +1 @@
-{"Abdominal pain upper ": 2.644528394223161, "Acute kidney injury ": 2.5930696006450025, "Adrenal cyst ": 3589.959076313897, "Angioedema ": 9.675285477397145, "Blood pressure increased ": 3.3731949253441567, "Completed suicide ": 9.776473580092135, "Disorientation ": 14.069035486146465, "Drug interaction ": 4.47462325957784, "Drug intolerance ": 5.28008056330669, "Feeling abnormal ": 5.182182794801889, "Gait disturbance ": 4.17521670958171, "Haemoglobin decreased ": 6.229015300163077, "Hyperkalaemia ": 7.974255272199924, "Hypertonic bladder ": 255.74431146299892, "Incontinence ": 54.16071193622556, "Macular degeneration ": 25.88607086778382, "Memory impairment ": 5.312704066005202, "Oedema peripheral ": 4.287485847828577, "Product dispensing error ": 40.20452458043525, "Renal impairment ": 4.018657817045645, "Somnolence ": 2.3274250506578853, "Toxicity to various agents ": 2.517962398323903}
\ No newline at end of file
+{"Bone pain": 22.1530615163487, "Chest pain": 3.674712311667832, "Neutropenia": 15.907607669357516, "Therapy non-responder": 33.21451693189232}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/130.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/130.json
index c778368ebbf..4e7d8eed118 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/130.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/130.json
@@ -1 +1 @@
-{"Aggression ": 11.30751142083474, "Confusional state ": 3.519031613972401, "Delirium ": 16.60492679529581, "Dizziness ": 2.466106202453957, "Drug interaction ": 6.528500494655908, "Hallucination ": 8.504855877447458, "Intentional overdose ": 10.644863180880686, "Restlessness ": 15.079259359001355, "Seizure ": 2.5009817973841013, "Somnolence ": 5.9768366257736085, "Suicide attempt ": 9.169613523031614, "Syncope ": 3.516029121483036}
\ No newline at end of file
+{"Adverse drug reaction": 5.390946362171228, "Breast cancer": 2.9666836350559715, "Carpal tunnel syndrome": 16.64895637450029, "Chronic kidney disease": 2.842399202243638, "Congenital aortic anomaly": 661.3487915994567, "Depression": 3.191581490384349, "Diabetic neuropathy": 35.56238215408991, "Encephalitis autoimmune": 73.92084513678424, "Fall": 2.075043306590516, "Fibromyalgia": 5.885271341552556, "Gait disturbance": 3.645469825828149, "Haemorrhoids": 8.12197157256277, "Hyperlipidaemia": 13.656772461726051, "Hypothyroidism": 3.309663239109815, "Illness": 2.0280015331854004, "Implant site swelling": 705.692691379214, "Influenza like illness": 2.1282097580792385, "Intrathecal pump insertion": 2637.989635161719, "Medical device removal": 565.2076161646444, "Medical device site infection": 1024.30826293848, "Memory impairment": 2.875625414103976, "Mitral valve prolapse": 127.31548808119884, "Multiple sclerosis": 51.35890540942624, "Multiple sclerosis relapse": 48.296963572785415, "Muscle spasticity": 44.12326087898434, "Muscular weakness": 2.519361723063112, "Neuropathy peripheral": 4.915939352194024, "Osteoarthritis": 5.046791503063728, "Pancreatitis": 2.5350633914946816, "Peptic ulcer": 51.30095304697913, "Psoriasis": 3.366688255638063, "Rhabdomyolysis": 3.1727553854225774, "Sleep apnoea syndrome": 17.603670599750913, "Staphylococcal infection": 21.753311287132703, "Stress": 5.4165163401991325, "Therapy non-responder": 5.702831530211742, "Urinary tract infection": 2.331712716218633}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/131.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/131.json
index e3c4cbb88d5..4886b37f1e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/131.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/131.json
@@ -1 +1 @@
-{"Neutropenia ": 32.3138873188415}
\ No newline at end of file
+{"Bronchopulmonary aspergillosis": 37.950786354948434, "Cardiac tamponade": 47.35308898612319, "Cellulitis": 6.827100509368127, "Cytokine release syndrome": 532.035408602709, "Cytokine storm": 207.16301814372397, "Cytopenia": 23.77286760434672, "Diffuse large B-cell lymphoma": 56.71476246147901, "Disease progression": 15.504676526452686, "Encephalopathy": 20.69605486978968, "Febrile neutropenia": 7.587044907758247, "Hypogammaglobulinaemia": 81.93672085599854, "Immune effector cell-associated neurotoxicity syndrome": 701.3511367824474, "Infection reactivation": 230.9584636332921, "Myelodysplastic syndrome": 21.785252719774228, "Myelosuppression": 4.29364959033556, "Neurotoxicity": 96.237660765208, "Neutropenia": 7.847011586047274, "Neutrophil count decreased": 3.941681416305357, "Off label use": 2.2464635496497904, "Pancytopenia": 7.408489041631926, "Platelet count decreased": 2.123433829948547, "Septic shock": 8.30347078718364, "Thrombocytopenia": 4.764399944149201, "Tumour lysis syndrome": 55.43007643811781, "White blood cell count decreased": 2.602999876440353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/132.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/132.json
index b23fd907980..21da2bcb8a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/132.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/132.json
@@ -1 +1 @@
-{"Asthenia ": 11.257891559444152, "Cystitis ": 286.7213948366054, "Dialysis ": 963.4787142268171, "Haemorrhage ": 62.75145750431325, "Illness ": 63.51362596336912, "Inflammation ": 114.64005417024296, "Weight decreased ": 31.288625526700592}
\ No newline at end of file
+{"Adrenal insufficiency": 11.390618423432263, "Adverse event": 2.340739994288312, "Alanine aminotransferase increased": 5.387885068004528, "Aphthous ulcer": 3.3664043864559674, "Aspartate aminotransferase increased": 4.499005982232157, "Blood bilirubin increased": 2.821124475125862, "Blood pressure increased": 2.268844956211335, "Blood thyroid stimulating hormone increased": 11.250223539662445, "Cardiac dysfunction": 17.493476301350345, "Colitis": 3.2693490986367117, "Decreased appetite": 2.914059233263263, "Dehydration": 2.396420978730648, "Diarrhoea": 4.9248501161947695, "Disease progression": 7.008684961472554, "Drug-induced liver injury": 4.033349501657896, "Dysphonia": 13.715147444908686, "Encephalitis": 6.39547186371706, "General physical health deterioration": 2.697322193247237, "Hepatic function abnormal": 4.787127700673955, "Hepatitis": 16.753390014848808, "Hepatotoxicity": 14.268333439404133, "Hypertension": 8.905206633327602, "Hyperthyroidism": 6.023734656797981, "Hypertransaminasaemia": 12.060992446014156, "Hypophagia": 3.743170092411594, "Hypophysitis": 17.30020283967958, "Hypopituitarism": 34.93162137773945, "Hypothyroidism": 27.569990326732736, "Immune-mediated adrenal insufficiency": 31.66471351948561, "Immune-mediated enterocolitis": 13.01462744852356, "Immune-mediated hepatic disorder": 87.09529715629557, "Immune-mediated hepatitis": 26.969937630686196, "Immune-mediated hyperthyroidism": 56.15157551640022, "Immune-mediated hypothyroidism": 75.92011247818438, "Immune-mediated myocarditis": 46.67011933359792, "Liver disorder": 3.371965966341956, "Liver function test increased": 4.286560121993948, "Liver injury": 2.781058730155713, "Malignant neoplasm progression": 19.181196921592857, "Metastases to lung": 8.410436113586357, "Metastatic renal cell carcinoma": 15.11998771999516, "Mucosal inflammation": 10.232368942309977, "Myasthenia gravis": 12.116320269294713, "Myocarditis": 2.9592380274296097, "Myositis": 9.9170114449366, "Neoplasm progression": 23.472344595380733, "Nephritis": 17.28791045060176, "Off label use": 2.498341491836728, "Osteonecrosis of jaw": 10.439589123311832, "Palmar-plantar erythrodysaesthesia syndrome": 21.530351283519924, "Pancreatitis acute": 2.1997530111795074, "Pneumonitis": 5.799894223368479, "Polycythaemia": 41.56815822263103, "Posterior reversible encephalopathy syndrome": 15.43194316514135, "Product use in unapproved indication": 2.499015900103504, "Proteinuria": 10.716961163246502, "Pulmonary mass": 3.929755940829143, "Renal cell carcinoma": 7.94735710109713, "Skin disorder": 2.0556010673778555, "Skin reaction": 2.8172524322460224, "Stomatitis": 5.028639021466682, "Therapy partial responder": 35.50011037493099, "Thyroid disorder": 4.204079321279239, "Thyroiditis": 18.149196867009262, "Transaminases increased": 6.056390275266433, "Tubulointerstitial nephritis": 6.646010823736642, "Type 1 diabetes mellitus": 5.43548937984069, "Weight decreased": 2.6923232928725342}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/133.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/133.json
index d82aa4ffb3d..45fd0e796ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/133.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/133.json
@@ -1 +1 @@
-{"Hyperbilirubinaemia ": 81.21165448975894, "Off label use ": 14.337032389729025, "Periorbital oedema ": 267.8413402999365}
\ No newline at end of file
+{"Aggression": 11.30751142083474, "Confusional state": 3.519031613972401, "Delirium": 16.60492679529581, "Dizziness": 2.4660890824827795, "Drug interaction": 6.528500494655908, "Hallucination": 8.504855877447458, "Intentional overdose": 10.644863180880686, "Restlessness": 15.078464057384542, "Seizure": 2.5007045823785146, "Somnolence": 5.976770742414698, "Suicide attempt": 9.169613523031614, "Syncope": 3.5159807361696007}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/134.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/134.json
index 385b208b84a..a849ae3b092 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/134.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/134.json
@@ -1 +1 @@
-{"Acute febrile neutrophilic dermatosis ": 18.82969268886989, "Acute graft versus host disease in skin ": 11.475916850729137, "Acute myeloid leukaemia ": 74.73891875752705, "Acute myeloid leukaemia recurrent ": 311.6572599101515, "Acute myeloid leukaemia refractory ": 316.805896993179, "Acute respiratory failure ": 3.998907967458603, "Agranulocytosis ": 3.956415070085957, "Anaemia ": 6.562574264637725, "Aspergillus infection ": 10.788052278201825, "Bacillus infection ": 97.91668952419596, "Bacteraemia ": 23.173383842655763, "Blast cell count increased ": 75.60746659487052, "Bone marrow disorder ": 18.209017773186428, "Bone marrow failure ": 12.053733958989952, "Bradypnoea ": 13.955491513341414, "Bronchopulmonary aspergillosis ": 9.467144769669227, "COVID-19 pneumonia ": 5.022562084400602, "Candida infection ": 4.14091601393544, "Cardiomyopathy ": 4.3059031483059576, "Chronic graft versus host disease ": 12.588829711661024, "Clostridium difficile infection ": 4.311910718609019, "Congenital aplasia ": 18.133066178684484, "Cytomegalovirus infection reactivation ": 8.56835259258077, "Cytopenia ": 60.88229519497963, "Disease progression ": 4.20052370793295, "Disease recurrence ": 3.2231194505925878, "Drug resistance ": 2.460042616203085, "Ejection fraction decreased ": 2.48437801264004, "Epstein-Barr virus infection reactivation ": 21.448494226992747, "Febrile neutropenia ": 57.72506348179317, "Full blood count decreased ": 4.470106748047323, "Fungaemia ": 27.554173674062927, "Fungal infection ": 8.866809752405775, "Gene mutation ": 22.397063404129423, "Graft versus host disease ": 7.677888281745559, "Graft versus host disease in skin ": 13.551880321876038, "Granulocyte count decreased ": 38.3197928802718, "Haematotoxicity ": 45.96069004427152, "Haemodynamic instability ": 9.609600102688969, "Haemoglobin decreased ": 2.012720730019101, "Haemophagocytic lymphohistiocytosis ": 14.078457478158864, "Hepatic failure ": 2.084752138218937, "Hyperbilirubinaemia ": 2.2584543690588026, "Infection ": 5.6438588113847, "JC virus infection ": 47.00734851353359, "Leukocytosis ": 3.7453140505611313, "Leukopenia ": 2.618180303770428, "Lung infiltration ": 3.9712134913622257, "Lymphocyte count decreased ": 4.51923658288471, "Malignant neoplasm progression ": 2.0528288742589726, "Meningitis ": 11.329537963438954, "Minimal residual disease ": 124.9021968373036, "Mucosal inflammation ": 2.2990966643045407, "Multiple organ dysfunction syndrome ": 4.130361469672551, "Myelodysplastic syndrome ": 20.665504242509662, "Myelosuppression ": 28.384324838937022, "Myocardial ischaemia ": 4.443949324395582, "Neutropenia ": 16.005021914560267, "Neutropenic colitis ": 31.263827805238563, "Neutropenic sepsis ": 38.46956013909756, "Neutrophil count decreased ": 7.995821449336806, "Off label use ": 4.278068345537489, "Pancytopenia ": 12.151355792967754, "Photophobia ": 2.110448223421736, "Platelet count decreased ": 5.2840529728928205, "Pneumocystis jirovecii pneumonia ": 4.810503632835713, "Pneumonia ": 3.904417489215523, "Pneumonia fungal ": 52.381814793976176, "Pneumonitis ": 4.512906102551736, "Pneumothorax ": 7.678725651460646, "Product use in unapproved indication ": 2.016403298573421, "Progressive multifocal leukoencephalopathy ": 16.383356634562368, "Pseudomonal bacteraemia ": 68.5374381551583, "Respiratory distress ": 2.457462934831252, "Respiratory failure ": 2.807957313353412, "Respiratory tract infection ": 2.3763094965132394, "Second primary malignancy ": 5.261337700330448, "Sepsis ": 6.071747332350092, "Septic shock ": 9.87379374040063, "Serum ferritin increased ": 13.399058781761836, "Splenomegaly ": 6.040376250849704, "Staphylococcal bacteraemia ": 21.238791734885112, "Staphylococcal sepsis ": 16.212030770111898, "Stenotrophomonas infection ": 33.18064330827153, "Systemic candida ": 26.5420189444426, "Therapeutic product effect incomplete ": 3.207622870808815, "Therapy non-responder ": 2.171243752700478, "Therapy partial responder ": 8.661754146913392, "Thrombocytopenia ": 10.112357785873856, "Tumour lysis syndrome ": 72.42978168997577, "Unevaluable event ": 2.290218840538167, "Venoocclusive liver disease ": 14.185020840545617, "White blood cell count abnormal ": 14.751921149380658, "White blood cell count decreased ": 6.574248365810278}
\ No newline at end of file
+{"Neutropenia": 32.31249790612925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/135.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/135.json
index 914563d047a..fef54d1183b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/135.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/135.json
@@ -1 +1 @@
-{"Epidermal necrosis ": 1291.3632998222286, "Haemoglobin decreased ": 42.1372592140456, "Nikolsky's sign ": 1296.5589549937945, "Off label use ": 8.40484346734086, "Rash erythematous ": 26.19745515552989, "Rash papular ": 109.99182813888548, "Toxic epidermal necrolysis ": 188.7290780133875}
\ No newline at end of file
+{"Asthenia": 11.2574437851239, "Cystitis": 286.7213948366054, "Dialysis": 963.4787142268171, "Haemorrhage": 62.75145750431325, "Illness": 63.51362596336912, "Inflammation": 114.6342502272756, "Weight decreased": 31.288625526700592}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/136.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/136.json
index c3993ae68fb..d467804777e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/136.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/136.json
@@ -1 +1 @@
-{"Actinic keratosis ": 18.110542398735, "Acute graft versus host disease ": 6.137959921782581, "Acute hepatic failure ": 2.640490827396351, "Alanine aminotransferase increased ": 2.0721269821970485, "Anal fissure ": 10.507514332225952, "Antineutrophil cytoplasmic antibody positive ": 46.01920140651239, "Arteriosclerosis ": 6.047843027211649, "Arteriosclerosis coronary artery ": 7.776722063299803, "Arthritis ": 2.199008872674337, "Aspergillus infection ": 4.297640527661327, "Autoscopy ": 166.45061512156218, "Bacteraemia ": 2.9763327062180025, "Basal cell carcinoma ": 5.791842799890136, "Bone erosion ": 5.750505770324966, "Bone marrow failure ": 2.81029504019246, "Bowen's disease ": 28.60412308755833, "Breath sounds abnormal ": 2.860074264859325, "Bronchopulmonary aspergillosis ": 3.188113090439413, "C-reactive protein abnormal ": 6.863650239501189, "C-reactive protein increased ": 2.307522088256549, "Candida infection ": 2.8468750057959404, "Central nervous system lesion ": 3.0411762716033883, "Cerebral atrophy ": 4.414156399113344, "Chronic allograft nephropathy ": 23.008132291208053, "Chronic gastrointestinal bleeding ": 92.54985200379114, "Chronic graft versus host disease ": 21.575669343844865, "Clear cell renal cell carcinoma ": 85.34361420446479, "Clostridium difficile infection ": 4.470428653911436, "Colitis ": 9.343537391031086, "Colitis ulcerative ": 9.732036292418076, "Concussion ": 3.740409511989313, "Condition aggravated ": 2.8368053394147976, "Conjunctivitis allergic ": 26.38942248531261, "Coombs positive haemolytic anaemia ": 76.26573182148286, "Coronary angioplasty ": 11.629214092381131, "Coronavirus infection ": 3.654108917992733, "Crohn's disease ": 11.950131938261547, "Cushingoid ": 5.45094475326935, "Cytomegalovirus chorioretinitis ": 10.984491409074597, "Cytomegalovirus colitis ": 8.75983465290404, "Cytomegalovirus infection ": 8.515328653531174, "Cytomegalovirus infection reactivation ": 9.17248510227432, "Cytomegalovirus test positive ": 9.3274580030513, "Cytomegalovirus viraemia ": 11.486706916890975, "Cytopenia ": 2.1262446092660165, "Defaecation urgency ": 5.980644113780618, "Dermatitis acneiform ": 3.676450076340119, "Diffuse large B-cell lymphoma ": 3.615964540311902, "Disease recurrence ": 4.998667833221429, "Disseminated intravascular coagulation ": 2.023234249621292, "Disseminated tuberculosis ": 8.433427005403283, "Drug hypersensitivity ": 4.083193918170512, "Drug ineffective ": 3.10091104297934, "Drug ineffective for unapproved indication ": 5.139986565293716, "Drug intolerance ": 6.483061164382083, "Drug specific antibody present ": 15.009365499079523, "Drug tolerance ": 5.221377074685469, "Drug-induced liver injury ": 2.1244589927835262, "Dust allergy ": 33.738508942202245, "Elbow deformity ": 102.90189639305636, "Enterococcal sepsis ": 28.706973867330056, "Enthesopathy ": 14.581936040276007, "Eosinophil count increased ": 6.863199150323931, "Eosinophilic granulomatosis with polyangiitis ": 23.017416920981383, "Epstein-Barr virus infection ": 15.582378315245045, "Erysipelas ": 4.114928242346909, "Exposure during pregnancy ": 2.677519140411743, "Faecal calprotectin increased ": 17.769401386261116, "Foetal anaemia ": 385.2330306315093, "Foetal exposure during pregnancy ": 3.7882817046004913, "Foetal growth restriction ": 13.827001883833129, "Forced expiratory volume decreased ": 19.321465843131357, "Frequent bowel movements ": 2.621922347805954, "Full blood count abnormal ": 4.928296576220172, "Fungal infection ": 2.144788536151914, "Fungal skin infection ": 11.052160059673248, "Gastroenteritis viral ": 3.2424489844519577, "Gastrointestinal disorder ": 3.5807988433284117, "Glucose tolerance impaired ": 3.7614694105568063, "Graft versus host disease ": 6.007800761251951, "Graft versus host disease in gastrointestinal tract ": 7.32398369749477, "Graft versus host disease in skin ": 7.593960279878285, "Granuloma skin ": 7.127619649037255, "Haemodialysis ": 6.794969885066548, "Haemolysis ": 5.227546476503685, "Haemophagocytic lymphohistiocytosis ": 5.350029710164987, "Haemoptysis ": 5.4080638296531145, "Haemorrhage foetal ": 606.3711542686203, "Haemorrhage in pregnancy ": 82.92966050686984, "Heart transplant rejection ": 29.68019956029113, "Hepatic enzyme abnormal ": 4.561878525028004, "Hepatic enzyme increased ": 2.412777288382531, "Hepatic fibrosis ": 7.556311397360255, "Hepatitis ": 2.6453429131154853, "Hepatitis cholestatic ": 2.3646911202377066, "Hepatosplenomegaly ": 8.039601851458428, "Hepatotoxicity ": 4.2104512197865045, "Herpes simplex ": 6.36213953867438, "Hypercalcaemia ": 2.5112646875090454, "Hypertriglyceridaemia ": 2.821445566590874, "Hypoxia ": 2.29469075456051, "Ileectomy ": 127.64466264750872, "Immunosuppressant drug level decreased ": 11.780541869409744, "Immunosuppression ": 5.250550230153238, "Infantile diarrhoea ": 86.67039268480089, "Inflammation ": 6.387299244013867, "Inflammatory bowel disease ": 19.92681508052921, "Inflammatory marker increased ": 4.682405345044963, "Infusion site thrombosis ": 247.64097312952595, "Interstitial lung disease ": 2.4908487113778346, "Intestinal operation ": 25.37263652666409, "Intraocular pressure increased ": 7.893003272315204, "Jaw fracture ": 11.631778293340776, "Joint stiffness ": 2.1005775604798003, "Joint swelling ": 2.194248321956379, "Kidney transplant rejection ": 19.57229845532473, "Labile hypertension ": 49.36745107373852, "Large intestine perforation ": 4.666936805319956, "Left ventricular hypertrophy ": 3.47999432521569, "Leukopenia ": 2.392263054654869, "Listeriosis ": 24.7935458554767, "Live birth ": 24.80128137119303, "Liver function test abnormal ": 5.157451865912398, "Liver function test increased ": 7.461416820425723, "Liver transplant rejection ": 15.425809834275736, "Low birth weight baby ": 5.583130756397774, "Lung disorder ": 3.1405136066194923, "Lung infiltration ": 3.564204587004535, "Lupus nephritis ": 22.1436252960797, "Lymphadenitis ": 4.337383149966338, "Lymphocyte count abnormal ": 49.83377020343119, "Lymphopenia ": 4.64123551442051, "Lymphoproliferative disorder ": 19.26038188178627, "Marrow hyperplasia ": 32.88875257240407, "Maternal exposure during breast feeding ": 2.9652835003547784, "Maternal exposure during pregnancy ": 5.601539424357867, "Maternal exposure timing unspecified ": 19.048869196746463, "Meningitis meningococcal ": 58.2547894768026, "Migraine with aura ": 2.5572870575290905, "Mite allergy ": 34.478415398783895, "Multiple-drug resistance ": 2.3092151046247458, "Musculoskeletal stiffness ": 2.319022258181382, "Mycotic allergy ": 40.50645639063959, "Myositis ": 4.061141250784096, "Nephropathy toxic ": 4.340298309892899, "Neuritis ": 14.448614041635516, "Neurological symptom ": 8.177357930385789, "Neutrophil count increased ": 10.7690417071381, "New onset refractory status epilepticus ": 1014.4020018036178, "Night sweats ": 5.886355105520511, "Nocardiosis ": 12.606180355223923, "Nodule ": 7.139703819151822, "Normal newborn ": 32.666677823068795, "Normochromic normocytic anaemia ": 21.42457439127578, "Obstruction ": 8.068280361910475, "Obstructive airways disorder ": 4.070173335759971, "Off label use ": 2.179807098671753, "Oral candidiasis ": 2.4290633647920425, "Overlap syndrome ": 60.38527609623851, "Pancreatitis ": 3.7280473082584846, "Pancytopenia ": 2.868270710557398, "Pleuritic pain ": 4.999005142093742, "Pneumocystis jirovecii pneumonia ": 4.925131245361223, "Pneumonia cytomegaloviral ": 14.63531653190448, "Polyomavirus-associated nephropathy ": 18.84997598958276, "Portal hypertension ": 4.706648151379506, "Post transplant lymphoproliferative disorder ": 18.139088290645475, "Pregnancy ": 6.860174707098705, "Premature baby ": 10.316462656130298, "Premature delivery ": 13.080970261225012, "Premature labour ": 20.26522192784463, "Proctitis ": 2.036643531196846, "Product availability issue ": 2.416652703066004, "Product use in unapproved indication ": 2.191676028804119, "Product use issue ": 2.049137160534142, "Productive cough ": 4.019316168300148, "Progressive multifocal leukoencephalopathy ": 3.8713836987885566, "Pulmonary alveolar haemorrhage ": 11.911018052991563, "Pulmonary fibrosis ": 4.399167356291366, "Pulmonary mass ": 3.3309915556307703, "Pulmonary vasculitis ": 62.82146623877089, "Quality of life decreased ": 2.807755171683055, "Red blood cell sedimentation rate abnormal ": 21.619128731854133, "Red blood cell sedimentation rate increased ": 3.5424117679233014, "Renal mass ": 34.59938186326724, "Renal transplant failure ": 31.615239081221564, "Respiratory symptom ": 16.93933053982527, "Retinal detachment ": 2.3893031371314213, "Retinal scar ": 109.29148635965105, "SLE arthritis ": 129.12502074221308, "Scleroderma ": 11.453699101396577, "Seborrhoeic dermatitis ": 15.710317257862553, "Sepsis ": 3.60898994872856, "Septic shock ": 2.544504392466658, "Shock ": 3.114413123063571, "Sjogren's syndrome ": 4.836823935372974, "Skin infection ": 8.176515840480876, "Skin laceration ": 2.694060611014957, "Skin lesion ": 2.675930361005156, "Skin mass ": 3.2421426728743783, "Sleep disorder due to a general medical condition ": 3.64214162071811, "Small intestinal resection ": 47.65729174312905, "Social problem ": 5.157767562418332, "Spinal compression fracture ": 2.90366414692523, "Spirometry abnormal ": 124.58187121052684, "Splenomegaly ": 4.46097998486924, "Squamous cell carcinoma ": 2.644768195570089, "Squamous cell carcinoma of skin ": 15.960631102842264, "Steroid dependence ": 26.86950048888321, "Synovitis ": 4.107474104897267, "Systemic lupus erythematosus ": 2.3637118211156816, "Tenosynovitis ": 11.59638775536134, "Therapeutic product effect decreased ": 10.12217932289879, "Therapeutic product effect incomplete ": 5.233617026481319, "Thiopurine methyltransferase decreased ": 611.4963049857162, "Thought blocking ": 114.0109227821457, "Thrombotic microangiopathy ": 8.000987943929552, "Tooth disorder ": 6.584551236495692, "Total lung capacity abnormal ": 348.9041624827356, "Transplant rejection ": 9.66023080029516, "Treatment failure ": 10.166078604398397, "Tuberculosis ": 2.5388070411503327, "Tubulointerstitial nephritis ": 2.1236268743872397, "Type 2 lepra reaction ": 128.57006553652965, "Ulcer ": 2.9505975248937943, "Upper respiratory tract infection ": 4.36603488519, "Urosepsis ": 3.162755231820702, "Uveitis ": 2.245735817656659, "Vasculitis ": 10.690232438254762, "Viral infection ": 2.283382891570792, "Vitiligo ": 3.60662459649064, "Weight decreased ": 2.8158026776346405}
\ No newline at end of file
+{"Hyperbilirubinaemia": 81.21165448975894, "Off label use": 14.336467674414925, "Periorbital oedema": 267.8413402999365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/137.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/137.json
index d26cb052624..6cd3433afc0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/137.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/137.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 4.430084591115952, "Abnormal dreams ": 7.453715920437804, "Agitation ": 2.919359540835329, "Altered state of consciousness ": 2.5745269417249164, "Aphasia ": 9.769345836094898, "Ataxia ": 7.537200585877913, "Atrial fibrillation ": 2.075501152781852, "Balance disorder ": 5.513015280333005, "Binocular eye movement disorder ": 344.266326098229, "Bradykinesia ": 41.09599081372991, "Brain stem stroke ": 232.4543451655005, "Cerebellar stroke ": 196.65092767014187, "Cerebral hypoperfusion ": 238.31788633870607, "Chronic inflammatory demyelinating polyradiculoneuropathy ": 155.5359141649399, "Cognitive disorder ": 7.275579916835688, "Compulsive shopping ": 134.35493495481504, "Confusional state ": 4.985940526503135, "Delirium ": 5.111232322887941, "Delusion ": 8.154149563324761, "Depressed level of consciousness ": 2.5234116562268456, "Device use error ": 64.0807080143582, "Diplopia ": 4.4984197913379145, "Disturbance in attention ": 5.900616285031044, "Drug interaction ": 4.640938593139303, "Dysarthria ": 5.983267079969332, "Dyskinesia ": 37.07866629272099, "Dysphonia ": 3.058425191190832, "Dysstasia ": 7.9863613490555805, "Euphoric mood ": 15.180975836807365, "Eye pain ": 5.332908202461363, "Fall ": 4.031295360698806, "Freezing phenomenon ": 251.44086568418496, "Gait disturbance ": 5.82534501337816, "Gambling disorder ": 148.12390542308947, "General physical health deterioration ": 2.557411651368657, "Hallucination ": 14.574263652342466, "Hallucination, visual ": 25.5602279768312, "Hypersexuality ": 213.63336841416935, "Hyporesponsive to stimuli ": 82.41361293303027, "Impulse-control disorder ": 64.74050840141537, "Micturition urgency ": 21.221128594536346, "Mobility decreased ": 2.9072966027211464, "Movement disorder ": 3.906124373508813, "Myocardial ischaemia ": 14.943365240846106, "Nasal mucosal disorder ": 170.40505820682887, "Neuralgia ": 7.314318115155658, "Nocturia ": 29.023614939660504, "Obsessive-compulsive disorder ": 46.797422012772095, "Oedema peripheral ": 3.240014114926104, "Oliguria ": 13.40145811821922, "On and off phenomenon ": 344.7596214391791, "Orthostatic hypotension ": 15.49084771624942, "Parkinson's disease ": 33.47523438910083, "Parkinsonism ": 21.3905529021994, "Photopsia ": 37.23206085361342, "Post micturition dribble ": 1595.9617023553117, "Rectal haemorrhage ": 2.3938827784808345, "Restlessness ": 6.917620583942053, "Serotonin syndrome ": 11.671185138329973, "Sudden onset of sleep ": 61.26216181591614, "Suicide attempt ": 2.629735575778812, "Tremor ": 2.6205309650510564}
\ No newline at end of file
+{"Acute febrile neutrophilic dermatosis": 18.82969268886989, "Acute graft versus host disease in skin": 11.475916850729137, "Acute myeloid leukaemia": 74.73891875752705, "Acute myeloid leukaemia recurrent": 311.6572599101515, "Acute myeloid leukaemia refractory": 316.805896993179, "Acute respiratory failure": 3.998907967458603, "Agranulocytosis": 3.956415070085957, "Anaemia": 6.562574264637725, "Aspergillus infection": 10.788052278201825, "Bacillus infection": 97.91668952419596, "Bacteraemia": 23.173383842655763, "Blast cell count increased": 75.60746659487052, "Bone marrow disorder": 18.209017773186428, "Bone marrow failure": 12.053733958989952, "Bradypnoea": 13.955491513341414, "Bronchopulmonary aspergillosis": 9.467144769669227, "COVID-19 pneumonia": 5.022562084400602, "Candida infection": 4.14091601393544, "Cardiomyopathy": 4.3059031483059576, "Chronic graft versus host disease": 12.588829711661024, "Clostridium difficile infection": 4.311910718609019, "Congenital aplasia": 18.07612677823669, "Cytomegalovirus infection reactivation": 8.56835259258077, "Cytopenia": 60.83267129884074, "Disease progression": 4.20052370793295, "Disease recurrence": 3.2231194505925878, "Drug resistance": 2.460042616203085, "Ejection fraction decreased": 2.48437801264004, "Epstein-Barr virus infection reactivation": 21.448494226992747, "Febrile neutropenia": 57.72506348179317, "Full blood count decreased": 4.470106748047323, "Fungaemia": 27.554173674062927, "Fungal infection": 8.864341881982472, "Gene mutation": 22.397063404129423, "Graft versus host disease": 7.677888281745559, "Graft versus host disease in skin": 13.551880321876038, "Granulocyte count decreased": 38.3197928802718, "Haematotoxicity": 45.96069004427152, "Haemodynamic instability": 9.609600102688969, "Haemoglobin decreased": 2.012720730019101, "Haemophagocytic lymphohistiocytosis": 14.078457478158864, "Hepatic failure": 2.084752138218937, "Hyperbilirubinaemia": 2.2584543690588026, "Infection": 5.6438588113847, "JC virus infection": 47.00734851353359, "Leukocytosis": 3.7453140505611313, "Leukopenia": 2.6178500018659685, "Lung infiltration": 3.9712134913622257, "Lymphocyte count decreased": 4.51923658288471, "Malignant neoplasm progression": 2.0528288742589726, "Meningitis": 11.329537963438954, "Minimal residual disease": 124.9021968373036, "Mucosal inflammation": 2.2990966643045407, "Multiple organ dysfunction syndrome": 4.130361469672551, "Myelodysplastic syndrome": 20.665504242509662, "Myelosuppression": 28.384324838937022, "Myocardial ischaemia": 4.443949324395582, "Neutropenia": 16.004329295193667, "Neutropenic colitis": 31.263827805238563, "Neutropenic sepsis": 38.46956013909756, "Neutrophil count decreased": 7.995821449336806, "Off label use": 4.277899569440795, "Pancytopenia": 12.151355792967754, "Photophobia": 2.110253887541604, "Platelet count decreased": 5.2840529728928205, "Pneumocystis jirovecii pneumonia": 4.810503632835713, "Pneumonia": 3.904417489215523, "Pneumonia fungal": 52.381814793976176, "Pneumonitis": 4.512906102551736, "Pneumothorax": 7.678725651460646, "Product use in unapproved indication": 2.0163403753643445, "Progressive multifocal leukoencephalopathy": 16.383356634562368, "Pseudomonal bacteraemia": 68.5374381551583, "Respiratory distress": 2.457462934831252, "Respiratory failure": 2.8077252696461543, "Respiratory tract infection": 2.3763094965132394, "Second primary malignancy": 5.261337700330448, "Sepsis": 6.071747332350092, "Septic shock": 9.87379374040063, "Serum ferritin increased": 13.399058781761836, "Splenomegaly": 6.040376250849704, "Staphylococcal bacteraemia": 21.238791734885112, "Staphylococcal sepsis": 16.212030770111898, "Stenotrophomonas infection": 33.18064330827153, "Systemic candida": 26.5420189444426, "Therapeutic product effect incomplete": 3.207622870808815, "Therapy non-responder": 2.1710539905432444, "Therapy partial responder": 8.661754146913392, "Thrombocytopenia": 10.11140272202312, "Tumour lysis syndrome": 72.42978168997577, "Unevaluable event": 2.290218840538167, "Venoocclusive liver disease": 14.185020840545617, "White blood cell count abnormal": 14.751921149380658, "White blood cell count decreased": 6.574248365810278}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/138.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/138.json
index cedfb83e890..fc41efeaef2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/138.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/138.json
@@ -1 +1 @@
-{"Asthma ": 9.995585176547452, "Cataract ": 7.815669624254697, "Conjunctival hyperaemia ": 43.730374107185526, "Corneal oedema ": 96.09666368828076, "Dyspnoea ": 2.551894340827068, "Epidermal necrosis ": 844.2336356273643, "Eye irritation ": 11.497342259300076, "Eye pain ": 8.844785519530927, "Full blood count abnormal ": 37.54490072368649, "Glaucoma ": 22.032096395214975, "Haemoglobin decreased ": 25.915378552600057, "Intraocular pressure increased ": 58.93334586442949, "Loss of personal independence in daily activities ": 16.78487835844961, "Nikolsky's sign ": 1314.909636104503, "Off label use ": 5.530340655516756, "Rash erythematous ": 23.076098587609238, "Rash papular ": 69.24216472645077, "Sleep disorder due to a general medical condition ": 61.5249815100347, "Therapeutic product effect incomplete ": 17.83718082994475, "Toxic epidermal necrolysis ": 146.66405515416187, "Vision blurred ": 4.478210695257494, "Visual acuity reduced ": 16.361061148031908, "Visual impairment ": 5.181402587196589, "Wheezing ": 3.089160737706595}
\ No newline at end of file
+{"Epidermal necrosis": 1291.3632998222286, "Haemoglobin decreased": 42.1372592140456, "Nikolsky's sign": 1296.5589549937945, "Off label use": 8.404512429131053, "Rash erythematous": 26.19745515552989, "Rash papular": 109.97966294336204, "Toxic epidermal necrolysis": 188.7290780133875}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/139.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/139.json
index 554a3b89645..c700a804863 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/139.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/139.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.064464228115815, "Coma ": 3.954640347295145, "Cystic fibrosis ": 291.21197508291993, "Drug hypersensitivity ": 3.365402598431708, "Drug reaction with eosinophilia and systemic symptoms ": 8.919600813126442, "Drug resistance ": 14.390025647687796, "Eosinophilia ": 19.18348230403525, "Haemoptysis ": 6.239221114461407, "Hepatic enzyme increased ": 3.312947252087437, "Hepatic function abnormal ": 2.050770917060521, "Infection ": 3.182001480149856, "Infective pulmonary exacerbation of cystic fibrosis ": 112.58805987505896, "Multiple organ dysfunction syndrome ": 6.5848186566809535, "Off label use ": 2.2777791200898347, "Pathogen resistance ": 55.97792805790844, "Pneumonia ": 2.3354444439338824, "Pseudomonas infection ": 65.86105513431144, "Rash maculo-papular ": 3.864900755734383, "Renal impairment ": 2.0553352644625478, "Respiratory tract infection ": 18.13877969437827, "Septic shock ": 10.637145308357953, "Shock ": 11.323559073794, "Skin exfoliation ": 8.08104651117738, "Staphylococcal infection ": 11.905407732441558, "Tracheo-oesophageal fistula ": 751.2570500801398}
\ No newline at end of file
+{"Actinic keratosis": 18.10764881670049, "Acute graft versus host disease": 6.136979254056884, "Acute hepatic failure": 2.640068957236476, "Alanine aminotransferase increased": 2.071795853408968, "Anal fissure": 10.505835585316673, "Antineutrophil cytoplasmic antibody positive": 46.01184857854105, "Arteriosclerosis": 6.046876709575552, "Arteriosclerosis coronary artery": 7.775479516190434, "Arthritis": 2.2400656863007464, "Aspergillus infection": 4.296953895506367, "Autoscopy": 166.42401985200956, "Bacteraemia": 2.975857183261664, "Basal cell carcinoma": 5.790917392033506, "Bone erosion": 5.749587006472201, "Bone marrow failure": 2.8098460404915446, "Bowen's disease": 28.599553121843076, "Breath sounds abnormal": 2.8596173233211712, "Bronchopulmonary aspergillosis": 3.187603736888649, "C-reactive protein abnormal": 6.862553493140989, "C-reactive protein increased": 2.3071533649363314, "Candida infection": 2.846420148277303, "Central nervous system lesion": 3.0406904016815046, 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2.4904506559526896, "Intestinal operation": 25.368582931956578, "Intraocular pressure increased": 7.891742116740974, "Jaw fracture": 11.629919927165387, "Joint stiffness": 2.100241943417108, "Joint swelling": 2.193897666041273, "Kidney transplant rejection": 19.56917118070381, "Labile hypertension": 49.35956393741153, "Large intestine perforation": 4.6661911854694775, "Left ventricular hypertrophy": 3.479438348075796, "Leukopenia": 2.3915785812355157, "Listeriosis": 24.789584777465944, "Live birth": 24.79731797007889, "Liver function test abnormal": 5.156627725620802, "Liver function test increased": 7.46022446712782, "Liver transplant rejection": 15.42334531083933, "Low birth weight baby": 5.582238689907431, "Lung disorder": 3.140011776837567, "Lung infiltration": 3.56363512797919, "Lupus nephritis": 22.140087460022627, "Lymphadenitis": 4.335684203003407, "Lymphocyte count abnormal": 49.82580816031388, "Lymphopenia": 4.6404939428073, "Lymphoproliferative disorder": 19.25730463746662, "Marrow hyperplasia": 32.88349801891645, "Maternal exposure during breast feeding": 2.9648097360691885, "Maternal exposure during pregnancy": 5.600644107249742, "Maternal exposure timing unspecified": 19.045825555742734, "Meningitis meningococcal": 58.24548228299174, "Migraine with aura": 2.556878498033143, "Mite allergy": 34.47290653715975, "Multiple-drug resistance": 2.308846175579837, "Musculoskeletal stiffness": 2.318651667624773, "Mycotic allergy": 40.499984391675866, "Myositis": 4.060492389985598, "Nephropathy toxic": 4.3396048289088665, "Neuritis": 14.446305476996343, "Neurological symptom": 8.176051352920183, "Neutrophil count increased": 10.767321037092117, "New onset refractory status epilepticus": 1014.2399334891974, "Night sweats": 5.8854144301066045, "Nocardiosis": 12.604166323333622, "Nodule": 7.138563016099579, "Normal newborn": 32.661457823250295, "Normochromic normocytic anaemia": 21.421151204657374, "Obstruction": 8.066991343407365, "Obstructive airways disorder": 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"Pulmonary fibrosis": 4.398464435583432, "Pulmonary mass": 3.330459350855796, "Pulmonary vasculitis": 62.81142884676834, "Quality of life decreased": 2.807306579869609, "Red blood cell sedimentation rate abnormal": 21.615674350925325, "Red blood cell sedimentation rate increased": 3.5418457837800763, "Renal mass": 34.59385373289434, "Renal transplant failure": 31.61018801777916, "Respiratory symptom": 16.936624015530686, "Retinal detachment": 2.3889214086128563, "Retinal scar": 109.2740254531544, "SLE arthritis": 129.10439108054433, "Scleroderma": 11.451869142288906, "Seborrhoeic dermatitis": 15.707807254646918, "Sepsis": 3.608413176412063, "Septic shock": 2.544097823695441, "Shock": 3.113915494090917, "Sjogren's syndrome": 4.836051173277497, "Skin infection": 8.175209444210195, "Skin laceration": 2.693630188248217, "Skin lesion": 2.6755028007364663, "Skin mass": 3.2416246899638077, "Sleep disorder due to a general medical condition": 3.641559683161069, "Small intestinal resection": 47.64967782709621, "Social problem": 5.156943528712034, "Spinal compression fracture": 2.9032002412249613, "Spirometry abnormal": 124.56196605666882, "Splenomegaly": 4.460267221710462, "Squamous cell carcinoma": 2.64434565486228, "Squamous cell carcinoma of skin": 15.958080943523246, "Steroid dependence": 26.865207634171227, "Synovitis": 4.106817788563889, "Systemic lupus erythematosus": 2.363334129021855, "Tenosynovitis": 11.594534990739502, "Therapeutic product effect decreased": 10.120561489029209, "Therapeutic product effect incomplete": 5.232780578767459, "Thiopurine methyltransferase decreased": 611.3986152371257, "Thought blocking": 113.99270689651637, "Thrombotic microangiopathy": 7.9997095510508, "Tooth disorder": 6.583499153821766, "Total lung capacity abnormal": 348.8484176362208, "Transplant rejection": 9.658687321825788, "Treatment failure": 10.164453622450583, "Tuberculosis": 2.538401420806302, "Tubulointerstitial nephritis": 2.1232875788455337, "Type 2 lepra reaction": 128.54952425366668, "Ulcer": 2.9501261135963905, "Upper respiratory tract infection": 4.365337242954816, "Urosepsis": 3.1622499322884954, "Uveitis": 2.245377019003013, "Vasculitis": 10.688524123863145, "Viral infection": 2.283018067032186, "Vitiligo": 3.606048391896061, "Weight decreased": 2.815352605715004}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/14.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/14.json
index 6d35b0cf191..0bd62614901 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/14.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/14.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 8.553063250381046, "Alopecia ": 7.8681949820267825, "Anti-cyclic citrullinated peptide antibody positive ": 43.30790007239304, "Arthropathy ": 17.368259943870395, "Blister ": 15.569127133051085, "Confusional state ": 6.406938621179766, "Contraindicated product administered ": 18.46441229360237, "Contusion ": 13.452909459905571, "Discomfort ": 17.43727164043431, "Duodenal ulcer perforation ": 67.64089812316634, "Folliculitis ": 56.30894294731588, "Gastrointestinal disorder ": 14.64563067031852, "Glossodynia ": 26.077630807602503, "Hand deformity ": 36.31596680891196, "Helicobacter infection ": 67.5917558636739, "Hepatic enzyme increased ": 14.27090988199706, "Hypersensitivity ": 5.834682110638103, "Ill-defined disorder ": 32.997923253061934, "Impaired healing ": 43.76835572255833, "Infection ": 12.566858614856026, "Infusion related reaction ": 21.988815956056705, "Irritable bowel syndrome ": 51.21877906216128, "Joint swelling ": 11.752481310346198, "Lower respiratory tract infection ": 31.46455341163997, "Muscle injury ": 101.14402644684608, "Nasopharyngitis ": 11.813667041060732}
\ No newline at end of file
+{"Abdominal pain upper": 2.644528394223161, "Acute kidney injury": 2.5930696006450025, "Adrenal cyst": 3589.959076313897, "Angioedema": 9.675285477397145, "Blood pressure increased": 3.373135726292182, "Completed suicide": 9.776473580092135, "Disorientation": 14.069035486146465, "Drug interaction": 4.47462325957784, "Drug intolerance": 5.28008056330669, "Feeling abnormal": 5.1820830493482335, "Gait disturbance": 4.175141021995201, "Haemoglobin decreased": 6.229015300163077, "Hyperkalaemia": 7.973155901355311, "Hypertonic bladder": 255.74431146299892, "Incontinence": 54.16071193622556, "Macular degeneration": 25.88607086778382, "Memory impairment": 5.312704066005202, "Oedema peripheral": 4.287379898737746, "Product dispensing error": 40.20452458043525, "Renal impairment": 4.018657817045645, "Somnolence": 2.3273993966640725, "Toxicity to various agents": 2.517962398323903}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/140.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/140.json
index ef40b5c0497..dda93cfb25c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/140.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/140.json
@@ -1 +1 @@
-{"Blood glucose decreased ": 49.68690995851325, "Blood glucose increased ": 7.972321510755766, "Drug ineffective ": 4.14748100383315, "Eye pain ": 11.729345344384743, "Hypoglycaemia ": 45.51686243448775, "Hypoglycaemic unconsciousness ": 180.40315723235517, "Loss of consciousness ": 5.664399825894125, "Nasal discomfort ": 260.4657714333368, "Product dose omission issue ": 5.789049928819617, "Rhinalgia ": 681.5825439883189}
\ No newline at end of file
+{"Abnormal behaviour": 4.430084591115952, "Abnormal dreams": 7.453715920437804, "Agitation": 2.919359540835329, "Altered state of consciousness": 2.5745269417249164, "Aphasia": 9.767889780209902, "Ataxia": 7.537200585877913, "Atrial fibrillation": 2.075444499167431, "Balance disorder": 5.513015280333005, "Binocular eye movement disorder": 344.266326098229, "Bradykinesia": 41.09599081372991, "Brain stem stroke": 232.4543451655005, "Cerebellar stroke": 196.65092767014187, "Cerebral hypoperfusion": 238.31788633870607, "Chronic inflammatory demyelinating polyradiculoneuropathy": 155.5359141649399, "Cognitive disorder": 7.275579916835688, "Compulsive shopping": 134.35493495481504, "Confusional state": 4.985940526503135, "Delirium": 5.111232322887941, "Delusion": 8.154149563324761, "Depressed level of consciousness": 2.5234116562268456, "Device use error": 64.0807080143582, "Diplopia": 4.4984197913379145, "Disturbance in attention": 5.900616285031044, "Drug interaction": 4.640938593139303, "Dysarthria": 5.983267079969332, "Dyskinesia": 37.07866629272099, "Dysphonia": 3.058425191190832, "Dysstasia": 7.984543126913088, "Euphoric mood": 15.180975836807365, "Eye pain": 5.332908202461363, "Fall": 4.031191981150801, "Freezing phenomenon": 251.44086568418496, "Gait disturbance": 5.825239344432525, "Gambling disorder": 148.12390542308947, "General physical health deterioration": 2.557411651368657, "Hallucination": 14.574263652342466, "Hallucination, visual": 25.5602279768312, "Hypersexuality": 213.63336841416935, "Hyporesponsive to stimuli": 82.41361293303027, "Impulse-control disorder": 64.74050840141537, "Micturition urgency": 21.221128594536346, "Mobility decreased": 2.9072966027211464, "Movement disorder": 3.906124373508813, "Myocardial ischaemia": 14.943365240846106, "Nasal mucosal disorder": 170.40505820682887, "Neuralgia": 7.314318115155658, "Nocturia": 29.023614939660504, "Obsessive-compulsive disorder": 46.797422012772095, "Oedema peripheral": 3.239934027406613, "Oliguria": 13.40145811821922, "On and off phenomenon": 344.7596214391791, "Orthostatic hypotension": 15.48750813100114, "Parkinson's disease": 33.47523438910083, "Parkinsonism": 21.3905529021994, "Photopsia": 37.23206085361342, "Post micturition dribble": 1595.9617023553117, "Rectal haemorrhage": 2.3938827784808345, "Restlessness": 6.917255517134564, "Serotonin syndrome": 11.671185138329973, "Sudden onset of sleep": 61.26216181591614, "Suicide attempt": 2.629735575778812, "Tremor": 2.62043196002032}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/141.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/141.json
index 1e73f6e20db..af304038074 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/141.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/141.json
@@ -1 +1 @@
-{"Abortion induced ": 27.71601358098749, "Abortion spontaneous ": 5.522991508505197, "Acute hepatic failure ": 8.85580735725713, "Adverse event ": 3.444889351983542, "Alanine aminotransferase increased ": 11.98057454619779, "Ascites ": 6.507745034903077, "Aspartate aminotransferase increased ": 3.077827369054901, "Blood alkaline phosphatase increased ": 6.223079080843263, "Blood bilirubin increased ": 4.681813342421798, "Blood creatine phosphokinase increased ": 6.307651211340066, "Blood creatinine increased ": 3.239209824122114, "Blood lactate dehydrogenase increased ": 2.491706391072863, "Blood lactic acid increased ": 9.249199967021614, "Blood urea increased ": 6.882917689052484, "Cardiac failure acute ": 13.218519776758953, "Death ": 4.024978053400881, "Drug eruption ": 2.3097560264678463, "Drug ineffective ": 3.226699886492401, "Drug resistance ": 56.71241890902205, "Drug tolerance ": 54.379619228667366, "Exposure via body fluid ": 202.87908817627135, "Gamma-glutamyltransferase increased ": 4.92038040648754, "Generalised oedema ": 4.167501468500933, "Hepatic cancer ": 46.23848180227015, "Hepatic cirrhosis ": 21.07978926239514, "Hepatic encephalopathy ": 14.602783825908674, "Hepatic failure ": 8.603040182070085, "Hepatic function abnormal ": 2.002145938159553, "Hepatitis B ": 68.1807118252519, "Hepatitis B DNA increased ": 1452.9984802120198, "Hepatitis B reactivation ": 56.961362588635126, "Hepatocellular carcinoma ": 27.412576373237403, "Hospitalisation ": 3.7727952993017633, "Jaundice ": 4.588502279679656, "Lactic acidosis ": 9.605478540840526, "Lipase increased ": 6.024164602347864, "Liver disorder ": 8.605807127052278, "Liver injury ": 3.5877528418912026, "Liver transplant ": 43.0860132100201, "Lymphoma ": 5.541480638555672, "Maternal exposure during pregnancy ": 3.500331343764132, "Neoplasm malignant ": 2.8650002289867538, "No adverse event ": 3.566535628533104, "Pancytopenia ": 2.9125412406315285, "Paternal exposure timing unspecified ": 131.9844283127463, "Pregnancy ": 17.417996214854522, "Product quality issue ": 2.1234511509134344, "Renal failure ": 2.0194880397442945, "Renal impairment ": 3.99065945160717, "Surgery ": 4.843632526410175, "Suspected counterfeit product ": 89.52784781182268, "Therapeutic response decreased ": 9.067227968088512, "Thrombotic microangiopathy ": 17.811544225557494, "Transaminases increased ": 5.250339805973239, "Treatment noncompliance ": 5.368834014042079, "Viral load increased ": 166.47896318073563, "Virologic failure ": 56.15312567319019}
\ No newline at end of file
+{"Asthma": 9.995585176547452, "Cataract": 7.815669624254697, "Conjunctival hyperaemia": 43.730374107185526, "Corneal oedema": 96.09666368828076, "Dyspnoea": 2.551856424858724, "Epidermal necrosis": 844.2336356273643, "Eye irritation": 11.497342259300076, "Eye pain": 8.844785519530927, "Full blood count abnormal": 37.54490072368649, "Glaucoma": 22.032096395214975, "Haemoglobin decreased": 25.915378552600057, "Intraocular pressure increased": 58.93334586442949, "Loss of personal independence in daily activities": 16.78487835844961, "Nikolsky's sign": 1314.909636104503, "Off label use": 5.530122770185807, "Rash erythematous": 23.076098587609238, "Rash papular": 69.23447835702649, "Sleep disorder due to a general medical condition": 61.5249815100347, "Therapeutic product effect incomplete": 17.83718082994475, "Toxic epidermal necrolysis": 146.66405515416187, "Vision blurred": 4.478210695257494, "Visual acuity reduced": 16.361061148031908, "Visual impairment": 5.181402587196589, "Wheezing": 3.089037889241122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/142.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/142.json
index 3e739a485c3..8fbe71a58f0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/142.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/142.json
@@ -1 +1 @@
-{"Cardio-respiratory arrest ": 26.3975180191986, "Completed suicide ": 44.89813050372836, "Overdose ": 8.749745194088035, "Toxicity to various agents ": 38.30106442042462}
\ No newline at end of file
+{"Acute kidney injury": 2.064464228115815, "Coma": 3.954640347295145, "Cystic fibrosis": 291.21197508291993, "Drug hypersensitivity": 3.365402598431708, "Drug reaction with eosinophilia and systemic symptoms": 8.918864062711494, "Drug resistance": 14.390025647687796, "Eosinophilia": 19.18348230403525, "Haemoptysis": 6.239221114461407, "Hepatic enzyme increased": 3.312947252087437, "Hepatic function abnormal": 2.050770917060521, "Infection": 3.182001480149856, "Infective pulmonary exacerbation of cystic fibrosis": 112.58805987505896, "Multiple organ dysfunction syndrome": 6.5848186566809535, "Off label use": 2.277689399552439, "Pathogen resistance": 55.97792805790844, "Pneumonia": 2.3354444439338824, "Pseudomonas infection": 65.86105513431144, "Rash maculo-papular": 3.864900755734383, "Renal impairment": 2.0553352644625478, "Respiratory tract infection": 18.13877969437827, "Septic shock": 10.637145308357953, "Shock": 11.323559073794, "Skin exfoliation": 8.08104651117738, "Staphylococcal infection": 11.905407732441558, "Tracheo-oesophageal fistula": 751.2570500801398}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/143.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/143.json
index df4e2ee9487..4fcf60b5035 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/143.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/143.json
@@ -1 +1 @@
-{"Arrhythmia ": 11.460978047712834, "Arthritis ": 65.7265361981178, "Blood folate decreased ": 5597.03623549758, "Cardiac arrest ": 16.209540481332596, "Drug ineffective ": 6.357140274324183, "Off label use ": 2.881082651748428, "Platelet count decreased ": 29.991794752000008, "Pneumonia ": 14.640098005305184, "Product use in unapproved indication ": 4.790899862496336}
\ No newline at end of file
+{"Blood glucose decreased": 49.68690995851325, "Blood glucose increased": 7.972321510755766, "Drug ineffective": 4.147450344648155, "Eye pain": 11.729345344384743, "Hypoglycaemia": 45.51532470215711, "Hypoglycaemic unconsciousness": 180.40315723235517, "Loss of consciousness": 5.66412263741087, "Nasal discomfort": 260.4657714333368, "Product dose omission issue": 5.789049928819617, "Rhinalgia": 681.5825439883189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/144.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/144.json
index 5927b1547eb..849e8cbf749 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/144.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/144.json
@@ -1 +1 @@
-{"Acute graft versus host disease in intestine ": 46.38427783947407, "Adenovirus infection ": 40.59654277619472, "Anuria ": 8.82062798509484, "Ascites ": 2.88510586472433, "Aspergillus infection ": 24.4099178951502, "BK virus infection ": 113.15181663826073, "Blood alkaline phosphatase increased ": 2.0495281416641, "Blood creatinine increased ": 5.074184380603878, "Bone marrow failure ": 10.24004835820816, "Bronchopulmonary aspergillosis ": 21.782374444423755, "Candida sepsis ": 83.3389577531939, "Chronic allograft nephropathy ": 304.555245457088, "Complications of transplanted kidney ": 385.94920878239367, "Cystitis haemorrhagic ": 21.471801644819102, "Cytomegalovirus colitis ": 80.2799663194893, "Cytomegalovirus enterocolitis ": 75.69565398023317, "Cytomegalovirus infection ": 104.89790707437676, "Cytomegalovirus infection reactivation ": 47.65441980889223, "Cytomegalovirus test positive ": 38.7675211700053, "Cytomegalovirus viraemia ": 110.03705505900382, "Cytopenia ": 6.106655348430063, "Disease recurrence ": 9.549150639687678, "Drug ineffective for unapproved indication ": 3.389537903435666, "Drug resistance ": 14.521440558411316, "Enterococcal infection ": 56.48677532816336, "Epstein-Barr virus infection ": 35.947028146079234, "Escherichia infection ": 23.617272533172518, "Glomerulosclerosis ": 151.73728268961497, "Graft versus host disease ": 19.152850863362566, "Graft versus host disease in gastrointestinal tract ": 82.80753994802072, "Graft versus host disease in skin ": 61.14477896990847, "Haematuria ": 4.774283069027482, "Human herpesvirus 6 infection ": 52.50389610471233, "Immunosuppressant drug level increased ": 27.704005804894063, "Kaposi's sarcoma ": 31.38938057871821, "Kidney fibrosis ": 60.67202096809904, "Kidney transplant rejection ": 237.7298029655598, "Klebsiella infection ": 28.51725129953702, "Leukopenia ": 5.887401224624318, "Liver transplant rejection ": 49.61194538204336, "Lung infiltration ": 7.891247692447439, "Lymphopenia ": 6.699503461802639, "Mucormycosis ": 37.53034447575481, "Multiple organ dysfunction syndrome ": 10.207100041941702, "Nephropathy ": 3.632196255333132, "Nephropathy toxic ": 25.10255011739549, "Neutropenia ": 2.427631852611056, "Nocardiosis ": 69.17041958208573, "Off label use ": 2.461509191075461, "Pancytopenia ": 5.230846874129729, "Pathogen resistance ": 16.922712759103167, "Pleural effusion ": 5.060201675862896, "Pneumocystis jirovecii pneumonia ": 29.856816599360705, "Pneumonia bacterial ": 10.052655217649246, "Polyomavirus-associated nephropathy ": 373.9499872182839, "Post transplant lymphoproliferative disorder ": 55.8031209991636, "Posterior reversible encephalopathy syndrome ": 11.779810246461874, "Product use in unapproved indication ": 4.91507111556063, "Proteinuria ": 5.278645075495335, "Pseudomonas infection ": 23.609301228922348, "Renal impairment ": 5.443871015433787, "Renal tubular disorder ": 15.117970114902938, "Renal tubular necrosis ": 27.10429770032339, "Respiratory failure ": 5.231258839369625, "Sepsis ": 2.937060749564783, "Septic shock ": 4.759676563143698, "Shock haemorrhagic ": 6.822520705231788, "Skin lesion ": 4.000702097071331, "Staphylococcal infection ": 4.604278733726862, "Systemic mycosis ": 73.45076368504093, "Therapeutic response decreased ": 3.120586472987656, "Thrombotic microangiopathy ": 30.361179545275668, "Transplant dysfunction ": 62.44376262482477, "Transplant failure ": 60.80451264147367, "Transplant rejection ": 159.5983932521416, "Tubulointerstitial nephritis ": 18.187241978353956, "Urinary tract infection ": 3.103544779536041, "Urine output decreased ": 11.94043871972373}
\ No newline at end of file
+{"Abortion induced": 27.71601358098749, "Abortion spontaneous": 5.522991508505197, "Acute hepatic failure": 8.85580735725713, "Adverse event": 3.444889351983542, "Alanine aminotransferase increased": 11.98057454619779, "Ascites": 6.507745034903077, "Aspartate aminotransferase increased": 3.077827369054901, "Blood alkaline phosphatase increased": 6.223079080843263, "Blood bilirubin increased": 4.681813342421798, "Blood creatine phosphokinase increased": 6.307651211340066, "Blood creatinine increased": 3.239209824122114, "Blood lactate dehydrogenase increased": 2.491706391072863, "Blood lactic acid increased": 9.249199967021614, "Blood urea increased": 6.882917689052484, "Cardiac failure acute": 13.218519776758953, "Death": 4.024978053400881, "Drug eruption": 2.3097560264678463, "Drug ineffective": 3.2266760172135664, "Drug resistance": 56.71241890902205, "Drug tolerance": 54.379619228667366, "Exposure via body fluid": 202.87908817627135, "Gamma-glutamyltransferase increased": 4.92038040648754, "Generalised oedema": 4.167501468500933, "Hepatic cancer": 46.23848180227015, "Hepatic cirrhosis": 21.07978926239514, "Hepatic encephalopathy": 14.602783825908674, "Hepatic failure": 8.603040182070085, "Hepatic function abnormal": 2.002145938159553, "Hepatitis B": 68.1807118252519, "Hepatitis B DNA increased": 1452.9984802120198, "Hepatitis B reactivation": 56.961362588635126, "Hepatocellular carcinoma": 27.412576373237403, "Hospitalisation": 3.7727952993017633, "Jaundice": 4.588502279679656, "Lactic acidosis": 9.605478540840526, "Lipase increased": 6.024164602347864, "Liver disorder": 8.605807127052278, "Liver injury": 3.5877528418912026, "Liver transplant": 43.0860132100201, "Lymphoma": 5.541480638555672, "Maternal exposure during pregnancy": 3.500331343764132, "Neoplasm malignant": 2.8650002289867538, "No adverse event": 3.566535628533104, "Pancytopenia": 2.9125412406315285, "Paternal exposure timing unspecified": 131.9844283127463, "Pregnancy": 17.417996214854522, "Product quality issue": 2.1234511509134344, "Renal failure": 2.0194880397442945, "Renal impairment": 3.99065945160717, "Surgery": 4.843632526410175, "Suspected counterfeit product": 89.52784781182268, "Therapeutic response decreased": 9.067227968088512, "Thrombotic microangiopathy": 17.811544225557494, "Transaminases increased": 5.250017981323682, "Treatment noncompliance": 5.368834014042079, "Viral load increased": 166.47896318073563, "Virologic failure": 56.15312567319019}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/145.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/145.json
index e80751aa889..281f9358d00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/145.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/145.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 29.40566573794465, "Alanine aminotransferase increased ": 2.9893862390982284, "Aphonia ": 11.55315777248286, "Aspartate aminotransferase increased ": 3.1973963114176462, "Blood creatinine increased ": 2.1602848864651096, "Blood lactate dehydrogenase increased ": 4.978233153990103, "Blood pressure increased ": 2.639365297454336, "Blood pressure systolic increased ": 7.94399100849343, "Blood thyroid stimulating hormone increased ": 18.57556911900037, "C-reactive protein increased ": 3.689249932575298, "Colitis ": 3.448389427707756, "Disease progression ": 14.28773988521418, "Dysphonia ": 11.912090996202645, "Hepatic function abnormal ": 5.424957449979547, "Hepatitis ": 4.956567357485743, "Hypertension ": 7.225008610698339, "Hyperthyroidism ": 14.328706484678364, "Hypothyroidism ": 41.53422504399764, "Infusion related reaction ": 30.263936496241936, "Liver disorder ": 4.64996926001087, "Myocarditis ": 7.7464849406626, "Myositis ": 27.05833074633933, "Neoplasm progression ": 23.7186344047527, "Oxygen saturation decreased ": 6.948926063799539, "Palmar-plantar erythrodysaesthesia syndrome ": 24.120606528277506, "Proteinuria ": 9.551171466749564, "Stomatitis ": 5.269570493226762, "Thyroiditis ": 37.2716292013344}
\ No newline at end of file
+{"Cardio-respiratory arrest": 26.3975180191986, "Completed suicide": 44.89813050372836, "Overdose": 8.749745194088035, "Toxicity to various agents": 38.30106442042462}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/146.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/146.json
index f9caac247e0..8d3b8bcc4ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/146.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/146.json
@@ -1 +1 @@
-{"Cerebrovascular accident ": 8.078429702206204, "Hypoaesthesia ": 6.687718745860841}
\ No newline at end of file
+{"Arrhythmia": 11.460978047712834, "Arthritis": 65.7265361981178, "Blood folate decreased": 5597.03623549758, "Cardiac arrest": 16.209540481332596, "Drug ineffective": 6.3570932782591525, "Off label use": 2.880969181320868, "Platelet count decreased": 29.991794752000008, "Pneumonia": 14.640098005305184, "Product use in unapproved indication": 4.790750472339156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/147.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/147.json
index 01a1a0cb057..08d323241eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/147.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/147.json
@@ -1 +1 @@
-{"Febrile neutropenia ": 29.681723734005992}
\ No newline at end of file
+{"Acute graft versus host disease in intestine": 46.38427783947407, "Adenovirus infection": 40.59654277619472, "Anuria": 8.82062798509484, "Ascites": 2.88510586472433, "Aspergillus infection": 24.4099178951502, "BK virus infection": 113.15181663826073, "Blood alkaline phosphatase increased": 2.0495281416641, "Blood creatinine increased": 5.074184380603878, "Bone marrow failure": 10.24004835820816, "Bronchopulmonary aspergillosis": 21.782374444423755, "Candida sepsis": 83.3389577531939, "Chronic allograft nephropathy": 304.555245457088, "Complications of transplanted kidney": 385.94920878239367, "Cystitis haemorrhagic": 21.471801644819102, "Cytomegalovirus colitis": 80.2799663194893, "Cytomegalovirus enterocolitis": 75.69565398023317, "Cytomegalovirus infection": 104.89790707437676, "Cytomegalovirus infection reactivation": 47.65441980889223, "Cytomegalovirus test positive": 38.7675211700053, "Cytomegalovirus viraemia": 110.03705505900382, "Cytopenia": 6.101796507160331, "Disease recurrence": 9.549150639687678, "Drug ineffective for unapproved indication": 3.389537903435666, "Drug resistance": 14.521440558411316, "Enterococcal infection": 56.48677532816336, "Epstein-Barr virus infection": 35.947028146079234, "Escherichia infection": 23.617272533172518, "Glomerulosclerosis": 151.73728268961497, "Graft versus host disease": 19.152850863362566, "Graft versus host disease in gastrointestinal tract": 82.80753994802072, "Graft versus host disease in skin": 61.14477896990847, "Haematuria": 4.774283069027482, "Human herpesvirus 6 infection": 52.50389610471233, "Immunosuppressant drug level increased": 27.704005804894063, "Kaposi's sarcoma": 31.38938057871821, "Kidney fibrosis": 60.67202096809904, "Kidney transplant rejection": 237.7298029655598, "Klebsiella infection": 28.51725129953702, "Leukopenia": 5.886658379164298, "Liver transplant rejection": 49.61194538204336, "Lung infiltration": 7.891247692447439, "Lymphopenia": 6.699503461802639, "Mucormycosis": 37.53034447575481, "Multiple organ dysfunction syndrome": 10.207100041941702, "Nephropathy": 3.632196255333132, "Nephropathy toxic": 25.10255011739549, "Neutropenia": 2.427527425764865, "Nocardiosis": 69.17041958208573, "Off label use": 2.4614122011559227, "Pancytopenia": 5.230846874129729, "Pathogen resistance": 16.922712759103167, "Pleural effusion": 5.0597354368566565, "Pneumocystis jirovecii pneumonia": 29.856816599360705, "Pneumonia bacterial": 10.052655217649246, "Polyomavirus-associated nephropathy": 373.9499872182839, "Post transplant lymphoproliferative disorder": 55.8031209991636, "Posterior reversible encephalopathy syndrome": 11.779810246461874, "Product use in unapproved indication": 4.914917708276403, "Proteinuria": 5.278645075495335, "Pseudomonas infection": 23.609301228922348, "Renal impairment": 5.443871015433787, "Renal tubular disorder": 15.117970114902938, "Renal tubular necrosis": 27.10429770032339, "Respiratory failure": 5.23082657207654, "Sepsis": 2.937060749564783, "Septic shock": 4.759676563143698, "Shock haemorrhagic": 6.822520705231788, "Skin lesion": 4.000702097071331, "Staphylococcal infection": 4.604278733726862, "Systemic mycosis": 73.45076368504093, "Therapeutic response decreased": 3.120586472987656, "Thrombotic microangiopathy": 30.361179545275668, "Transplant dysfunction": 62.44376262482477, "Transplant failure": 60.80451264147367, "Transplant rejection": 159.5983932521416, "Tubulointerstitial nephritis": 18.187241978353956, "Urinary tract infection": 3.103544779536041, "Urine output decreased": 11.94043871972373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/148.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/148.json
index 3521a810d3f..bea4fe225b3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/148.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/148.json
@@ -1 +1 @@
-{"Acute respiratory failure ": 7.586738868796107, "Affect lability ": 2.762911713375732, "Alanine aminotransferase increased ": 11.289581391857604, "Alcohol abuse ": 9.479007261780232, "Alcohol poisoning ": 16.803271022461573, "Amylase increased ": 3.8008549373551954, "Anaemia ": 5.101418975562086, "Ascites ": 2.4510172527365754, "Aspartate aminotransferase increased ": 13.235145261287148, "Bacterial infection ": 2.000699151960752, "Bilirubin conjugated increased ": 15.179544476593026, "Blood albumin decreased ": 20.64720499396428, "Blood bilirubin increased ": 2.5543675093740186, "Blood calcium decreased ": 15.0832713668674, "Blood chloride decreased ": 41.89213916216588, "Blood chloride increased ": 16.422352830707872, "Blood creatinine decreased ": 43.18891062902315, "Blood creatinine increased ": 2.749508125605104, "Blood magnesium decreased ": 45.58691371230553, "Blood potassium decreased ": 14.423660005932955, "Blood potassium increased ": 12.69000757519289, "Blood sodium decreased ": 23.183203866524103, "Blood thyroid stimulating hormone increased ": 8.214569741601311, "Brain oedema ": 7.484980463666909, "Bronchiectasis ": 10.230507396783027, "Bronchitis chronic ": 13.593554172192004, "Bronchopleural fistula ": 340.6205052791107, "Bundle branch block right ": 6.514673507977062, "Calculus urinary ": 15.420153145337034, "Candida infection ": 6.310084126652108, "Cardiac failure acute ": 4.330301833171965, "Cardiac failure chronic ": 7.646568244383743, "Cardiogenic shock ": 2.565180070042742, "Cardiomyopathy ": 3.888876601667241, "Cardiopulmonary failure ": 41.90646033197992, "Cholecystitis chronic ": 47.86832925553114, "Chronic obstructive pulmonary disease ": 3.1307061051173064, "Chronic respiratory failure ": 23.680890528521623, "Cor pulmonale ": 114.79615156336146, "Coronary artery disease ": 2.2083481095669883, "Creatinine renal clearance decreased ": 4.030159294361988, "Cystic lung disease ": 144.7026977687118, "Deafness ": 2.002107846030778, "Deafness neurosensory ": 7.786492816151993, "Decreased appetite ": 2.326960967715916, "Device related sepsis ": 36.35403431090956, "Drug resistance ": 4.198202117026216, "Drug-induced liver injury ": 5.110726163095057, "Duodenal perforation ": 34.31028382411531, "Dyspnoea ": 2.223247686968735, "Dyspnoea at rest ": 19.973183170338768, "Electrocardiogram QT prolonged ": 67.4492889910647, "Electrocardiogram T wave inversion ": 21.26716683437778, "Electrolyte imbalance ": 13.418130212401026, "Embolism ": 3.407040151654625, "Empyema ": 21.85038051409052, "Gastroenteritis ": 4.7031476010580295, "Generalised oedema ": 2.073654900839456, "Haematocrit decreased ": 3.288530461342508, "Haemoglobin decreased ": 9.691711705072974, "Haemoptysis ": 4.7528885389955535, "Hepatic enzyme increased ": 3.2968357089789104, "Hepatitis ": 7.728451731313643, "Hepatitis B ": 6.192876186137739, "Hepatitis B surface antigen positive ": 93.71277875548957, "Hepatitis C ": 2.311880269565149, "Hepatitis toxic ": 24.049799982381305, "Hepatomegaly ": 3.302878975172696, "Hepatosplenomegaly ": 15.39518701342432, "Hepatotoxicity ": 11.143482604644063, "Hiccups ": 6.972485855067602, "Hydronephrosis ": 4.571709955477257, "Hyperbilirubinaemia ": 4.010835628548893, "Hypoacusis ": 5.581938523428828, "Hypoalbuminaemia ": 5.222747348415804, "Hypocalcaemia ": 5.7005565431640655, "Hypokalaemia ": 5.101122412784428, "Hypomagnesaemia ": 24.27125694728228, "Hyponatraemia ": 2.1437416290772644, "Hypothermia ": 5.670450922014624, "Incorrect product administration duration ": 106.92682378638328, "Intentional product use issue ": 15.63819680324032, "Intracranial pressure increased ": 4.175270840027901, "Left ventricular hypertrophy ": 5.751340668676269, "Lung abscess ": 17.16613767832352, "Meningitis tuberculous ": 71.92468919821913, "Mitral valve incompetence ": 5.812120385904112, "Myocardial ischaemia ": 5.316367139528253, "Neuropathy peripheral ": 10.261718351525316, "Off label use ": 3.559169627663633, "Optic nerve disorder ": 27.34892358315133, "Optic neuritis ": 13.441853436674988, "Pancoast's tumour ": 661.4397568393958, "Peritonitis ": 3.046480804019243, "Platelet count decreased ": 2.255987249836561, "Platelet count increased ": 20.88064800573933, "Pleurisy ": 6.258773779897765, "Pneumothorax ": 26.054463571380836, "Poisoning ": 2.575154579114072, "Polyneuropathy ": 3.245713850429476, "Product availability issue ": 3.0077993634137505, "Product use in unapproved indication ": 3.045574780587207, "Productive cough ": 2.214394937605768, "Psychotic disorder ": 5.280063674277921, "Pulmonary arterial hypertension ": 7.800259158453333, "Pulmonary embolism ": 2.4872482502574926, "Pulmonary haemorrhage ": 5.979520117147652, "Pulmonary hypertension ": 2.5720151919328944, "Pulmonary oedema ": 2.3006129409785987, "Pulmonary tuberculosis ": 59.616926898268304, "Pyelonephritis ": 4.991611056082786, "Pyelonephritis chronic ": 101.42117345549948, "Red blood cell count increased ": 15.872177732558368, "Respiratory distress ": 4.531881974107412, "Respiratory failure ": 11.830108981004244, "Right ventricular dysfunction ": 28.69246175133772, "Right ventricular failure ": 7.348301898010085, "Shock haemorrhagic ": 2.864585034751503, "Sinus bradycardia ": 2.07513595212826, "Skin discolouration ": 2.4924144560078094, "Sputum culture positive ": 93.69305410831306, "Stenotrophomonas infection ": 29.902730725323096, "Sudden death ": 3.55551732828071, "Tachypnoea ": 2.693991802552421, "Toxic optic neuropathy ": 201.1815642919925, "Transaminases increased ": 3.1775667694290477, "Treatment failure ": 3.448128834514656, "Treatment noncompliance ": 10.921704923575964, "Tricuspid valve incompetence ": 19.80169817548116, "Tuberculosis ": 79.38512672191074, "Underdose ": 10.686852435306, "Urine output decreased ": 6.362609138555015, "Vascular encephalopathy ": 117.62320384450376, "Ventricular extrasystoles ": 7.571458519861368, "Vomiting ": 2.6780495181921333, "White blood cell count increased ": 14.275342261473712, "White blood cells urine positive ": 23.73431312126392}
\ No newline at end of file
+{"Adrenal insufficiency": 29.40566573794465, "Alanine aminotransferase increased": 2.9893862390982284, "Aphonia": 11.55315777248286, "Aspartate aminotransferase increased": 3.1973963114176462, "Blood creatinine increased": 2.1602848864651096, "Blood lactate dehydrogenase increased": 4.978233153990103, "Blood pressure increased": 2.639318967617881, "Blood pressure systolic increased": 7.94399100849343, "Blood thyroid stimulating hormone increased": 18.57556911900037, "C-reactive protein increased": 3.689249932575298, "Colitis": 3.448389427707756, "Disease progression": 14.28773988521418, "Dysphonia": 11.912090996202645, "Hepatic function abnormal": 5.424957449979547, "Hepatitis": 4.956567357485743, "Hypertension": 7.224933967525278, "Hyperthyroidism": 14.327401158905998, "Hypothyroidism": 41.53422504399764, "Infusion related reaction": 30.263936496241936, "Liver disorder": 4.64996926001087, "Myocarditis": 7.7464849406626, "Myositis": 27.05833074633933, "Neoplasm progression": 23.7186344047527, "Oxygen saturation decreased": 6.948554079882049, "Palmar-plantar erythrodysaesthesia syndrome": 24.120606528277506, "Proteinuria": 9.551171466749564, "Stomatitis": 5.269570493226762, "Thyroiditis": 37.2716292013344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/149.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/149.json
index a3b72a053de..3db36b53b82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/149.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/149.json
@@ -1 +1 @@
-{"Adverse event ": 29.4899366289344, "Cough ": 5.57457586435228, "Death ": 4.117188296088964, "Disease progression ": 21.492601542753423, "Inguinal hernia ": 398.911522618452, "Keratopathy ": 6664.325700344432, "Ocular toxicity ": 2921.8518615322105, "Off label use ": 6.583446680724551, "Plasma cell myeloma ": 81.30944715832501, "Platelet count decreased ": 9.395397853734124, "Thrombocytopenia ": 6.633606057169947, "Visual acuity reduced ": 74.72834515800422, "Visual impairment ": 14.39819922915318}
\ No newline at end of file
+{"Cerebrovascular accident": 8.078284142686709, "Hypoaesthesia": 6.687718745860841}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/15.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/15.json
index daa6cb3ea89..99b3d49cddc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/15.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/15.json
@@ -1 +1 @@
-{"Depression ": 4.811151319976349, "Drug dependence ": 197.37695047392972, "Emotional distress ": 11.540852615818826, "Overdose ": 11.59275491568321, "Suicidal ideation ": 8.057830598170321}
\ No newline at end of file
+{"Abdominal discomfort": 8.553063250381046, "Alopecia": 7.8681949820267825, "Anti-cyclic citrullinated peptide antibody positive": 43.30790007239304, "Arthropathy": 17.368259943870395, "Blister": 15.569127133051085, "Confusional state": 6.406938621179766, "Contraindicated product administered": 18.46441229360237, "Contusion": 13.452909459905571, "Discomfort": 17.43727164043431, "Duodenal ulcer perforation": 67.64089812316634, "Folliculitis": 56.30894294731588, "Gastrointestinal disorder": 14.645169581619932, "Glossodynia": 26.077630807602503, "Hand deformity": 36.31596680891196, "Helicobacter infection": 67.5917558636739, "Hepatic enzyme increased": 14.27090988199706, "Hypersensitivity": 5.834682110638103, "Ill-defined disorder": 32.997923253061934, "Impaired healing": 43.76835572255833, "Infection": 12.566858614856026, "Infusion related reaction": 21.988815956056705, "Irritable bowel syndrome": 51.21877906216128, "Joint swelling": 11.752481310346198, "Lower respiratory tract infection": 31.46455341163997, "Muscle injury": 101.14402644684608, "Nasopharyngitis": 11.812767047058896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/150.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/150.json
index 56a4033900b..5af91ff6db3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/150.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/150.json
@@ -1 +1 @@
-{"Off label use ": 4.082829155590815, "Urinary tract infection ": 16.386387938060963}
\ No newline at end of file
+{"Febrile neutropenia": 29.681723734005992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/151.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/151.json
index ca64b99b38c..6dfd32b46ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/151.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/151.json
@@ -1 +1 @@
-{"Acne ": 4.987092114352351, "Arthritis ": 11.67689489268312, "Arthropathy ": 5.827965804454518, "Blood cholesterol ": 502.00280067980657, "Blood cholesterol abnormal ": 60.07266253242842, "Blood pressure decreased ": 8.327027918230938, "Blood pressure increased ": 3.942898051325023, "Bronchitis ": 4.36990534305016, "Calcinosis ": 251.7007607167891, "Cystitis ": 5.0608465792277615, "Diabetes mellitus ": 2.205510694192626, "Diverticulitis ": 4.885846385773479, "Gait disturbance ": 2.3867051105033426, "Gastrointestinal disorder ": 2.65490482008081, "Hand deformity ": 14.616996410922086, "Hypersomnia ": 26.559866388981927, "Immune system disorder ": 8.776419611016381, "Inflammation ": 7.592577911403811, "Joint dislocation ": 69.43455530613893, "Kidney infection ": 49.62409140117257, "Loss of personal independence in daily activities ": 9.13361982811423, "Lower respiratory tract infection ": 5.316073800425885, "Migraine with aura ": 18.825022305191485, "Multiple allergies ": 91.81517002415158, "Nasopharyngitis ": 5.546520932349633, "Nephrolithiasis ": 21.24616349238205, "Personality change due to a general medical condition ": 3441.48211353264, "Photophobia ": 3.680925238878539, "Poor quality sleep ": 17.64763999737211, "Product dose omission issue ": 6.605336591084175, "Renal disorder ": 16.598411222300783, "SLE arthritis ": 2302.5150139179664, "Sinusitis ": 3.493238138392944, "Skin induration ": 120.83288024406104, "Skin lesion ": 4.764061773365795, "Social problem ": 85.62767969823344, "Spinal disorder ": 58.04743129635512, "Systemic lupus erythematosus ": 12.792718898788204, "Urinary tract infection ": 2.1392731127664946, "Urine abnormality ": 185.6437364662365, "Varicose vein ": 90.30049662250867, "Vein disorder ": 142.91539099639402, "Walking aid user ": 127.29738705648506}
\ No newline at end of file
+{"Acute respiratory failure": 7.586738868796107, "Affect lability": 2.762911713375732, "Alanine aminotransferase increased": 11.289581391857604, "Alcohol abuse": 9.479007261780232, "Alcohol poisoning": 16.803271022461573, "Amylase increased": 3.8008549373551954, "Anaemia": 5.101418975562086, "Ascites": 2.4510172527365754, "Aspartate aminotransferase increased": 13.235145261287148, "Bacterial infection": 2.000699151960752, "Bilirubin conjugated increased": 15.179544476593026, "Blood albumin decreased": 20.64720499396428, "Blood bilirubin increased": 2.5543675093740186, "Blood calcium decreased": 15.0832713668674, "Blood chloride decreased": 41.89213916216588, "Blood chloride increased": 16.422352830707872, "Blood creatinine decreased": 43.18891062902315, "Blood creatinine increased": 2.749508125605104, "Blood magnesium decreased": 45.58691371230553, "Blood potassium decreased": 14.423660005932955, "Blood potassium increased": 12.69000757519289, "Blood sodium decreased": 23.183203866524103, "Blood thyroid stimulating hormone increased": 8.214569741601311, "Brain oedema": 7.484980463666909, "Bronchiectasis": 10.230507396783027, "Bronchitis chronic": 13.593554172192004, "Bronchopleural fistula": 340.6205052791107, "Bundle branch block right": 6.514673507977062, "Calculus urinary": 15.420153145337034, "Candida infection": 6.310084126652108, "Cardiac failure acute": 4.330301833171965, "Cardiac failure chronic": 7.646568244383743, "Cardiogenic shock": 2.565180070042742, "Cardiomyopathy": 3.888876601667241, "Cardiopulmonary failure": 41.90646033197992, "Cholecystitis chronic": 47.86832925553114, "Chronic obstructive pulmonary disease": 3.1307061051173064, "Chronic respiratory failure": 23.680890528521623, "Cor pulmonale": 114.79615156336146, "Coronary artery disease": 2.2083481095669883, "Creatinine renal clearance decreased": 4.030159294361988, "Cystic lung disease": 144.7026977687118, "Deafness": 2.002107846030778, "Deafness neurosensory": 7.786492816151993, "Decreased appetite": 2.3269383665857117, "Device related sepsis": 36.35403431090956, "Drug resistance": 4.198202117026216, "Drug-induced liver injury": 5.110413768559919, "Duodenal perforation": 34.31028382411531, "Dyspnoea": 2.2232146144571634, "Dyspnoea at rest": 19.973183170338768, "Electrocardiogram QT prolonged": 67.4492889910647, "Electrocardiogram T wave inversion": 21.26716683437778, "Electrolyte imbalance": 13.418130212401026, "Embolism": 3.407040151654625, "Empyema": 21.85038051409052, "Gastroenteritis": 4.7031476010580295, "Generalised oedema": 2.073654900839456, "Haematocrit decreased": 3.288530461342508, "Haemoglobin decreased": 9.691711705072974, "Haemoptysis": 4.7528885389955535, "Hepatic enzyme increased": 3.2968357089789104, "Hepatitis": 7.728451731313643, "Hepatitis B": 6.192876186137739, "Hepatitis B surface antigen positive": 93.71277875548957, "Hepatitis C": 2.311880269565149, "Hepatitis toxic": 24.049799982381305, "Hepatomegaly": 3.302878975172696, "Hepatosplenomegaly": 15.39518701342432, "Hepatotoxicity": 11.143482604644063, "Hiccups": 6.972485855067602, "Hydronephrosis": 4.571709955477257, "Hyperbilirubinaemia": 4.010835628548893, "Hypoacusis": 5.581467396940961, "Hypoalbuminaemia": 5.222747348415804, "Hypocalcaemia": 5.7005565431640655, "Hypokalaemia": 5.101122412784428, "Hypomagnesaemia": 24.27125694728228, "Hyponatraemia": 2.1437416290772644, "Hypothermia": 5.670450922014624, "Incorrect product administration duration": 106.92682378638328, "Intentional product use issue": 15.63819680324032, "Intracranial pressure increased": 4.175270840027901, "Left ventricular hypertrophy": 5.751340668676269, "Lung abscess": 17.16613767832352, "Meningitis tuberculous": 71.92468919821913, "Mitral valve incompetence": 5.812120385904112, "Myocardial ischaemia": 5.316367139528253, "Neuropathy peripheral": 10.261404891204217, "Off label use": 3.5590291491078303, "Optic nerve disorder": 27.34892358315133, "Optic neuritis": 13.441853436674988, "Pancoast's tumour": 661.4397568393958, "Peritonitis": 3.046480804019243, "Platelet count decreased": 2.255987249836561, "Platelet count increased": 20.88064800573933, "Pleurisy": 6.258773779897765, "Pneumothorax": 26.054463571380836, "Poisoning": 2.575154579114072, "Polyneuropathy": 3.245713850429476, "Product availability issue": 3.0077993634137505, "Product use in unapproved indication": 3.045479638418408, "Productive cough": 2.214394937605768, "Psychotic disorder": 5.280063674277921, "Pulmonary arterial hypertension": 7.800259158453333, "Pulmonary embolism": 2.4872482502574926, "Pulmonary haemorrhage": 5.979520117147652, "Pulmonary hypertension": 2.5720151919328944, "Pulmonary oedema": 2.300310554403805, "Pulmonary tuberculosis": 59.616926898268304, "Pyelonephritis": 4.991611056082786, "Pyelonephritis chronic": 101.42117345549948, "Red blood cell count increased": 15.872177732558368, "Respiratory distress": 4.531881974107412, "Respiratory failure": 11.829125219275218, "Right ventricular dysfunction": 28.69246175133772, "Right ventricular failure": 7.348301898010085, "Shock haemorrhagic": 2.864585034751503, "Sinus bradycardia": 2.07513595212826, "Skin discolouration": 2.4924144560078094, "Sputum culture positive": 93.69305410831306, "Stenotrophomonas infection": 29.902730725323096, "Sudden death": 3.55551732828071, "Tachypnoea": 2.6936083247663296, "Toxic optic neuropathy": 201.1815642919925, "Transaminases increased": 3.1773718548340395, "Treatment failure": 3.448128834514656, "Treatment noncompliance": 10.921704923575964, "Tricuspid valve incompetence": 19.80169817548116, "Tuberculosis": 79.38512672191074, "Underdose": 10.686852435306, "Urine output decreased": 6.362609138555015, "Vascular encephalopathy": 117.62320384450376, "Ventricular extrasystoles": 7.571458519861368, "Vomiting": 2.678013335125181, "White blood cell count increased": 14.272584841663406, "White blood cells urine positive": 23.73431312126392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/152.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/152.json
index b32221ebde1..4a1dd3bad71 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/152.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/152.json
@@ -1 +1 @@
-{"Abdominal pain lower ": 79.10508326271024, "Ascites ": 161.00914269102768, "Dyspnoea ": 2.2847065573708543, "Ovarian hyperstimulation syndrome ": 1748.431010687586}
\ No newline at end of file
+{"Adverse event": 29.4899366289344, "Cough": 5.574524162573224, "Death": 4.117188296088964, "Disease progression": 21.492601542753423, "Inguinal hernia": 398.911522618452, "Keratopathy": 6664.325700344432, "Ocular toxicity": 2921.8518615322105, "Off label use": 6.583187386327942, "Plasma cell myeloma": 81.30944715832501, "Platelet count decreased": 9.395397853734124, "Thrombocytopenia": 6.632982090720838, "Visual acuity reduced": 74.72834515800422, "Visual impairment": 14.39819922915318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/153.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/153.json
index 4805f06e743..3e8fc848121 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/153.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/153.json
@@ -1 +1 @@
-{"Myalgia ": 13.98203209107439}
\ No newline at end of file
+{"Off label use": 4.082668356417496, "Urinary tract infection": 16.386387938060963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/154.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/154.json
index 4f895fe399a..3eb5485e999 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/154.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/154.json
@@ -1 +1 @@
-{"Accidental exposure to product ": 3.4356332218278096, "Adverse drug reaction ": 3.0537326151522164, "Antiphospholipid syndrome ": 6.886619903555781, "Arthritis ": 2.818988549588164, "Bacterial infection ": 2.736413516238663, "Bedridden ": 2.5178329136492925, "Blood cholesterol abnormal ": 3.3069041875687133, "Blood test abnormal ": 2.617379042781179, "Brain fog ": 2.1332784180768622, "Bronchitis ": 3.955046991806376, "Butterfly rash ": 28.126996441217948, "Calcinosis ": 7.49986041760068, "Cardiac operation ": 2.7978749982041404, "Cataract operation ": 3.2524693257018487, "Catarrh ": 4.284805757933276, "Cellulitis ": 2.804685630571506, "Central nervous system lupus ": 133.52816334255775, "Cerebrospinal fluid leakage ": 8.395179214702706, "Cholecystectomy ": 2.596454991117624, "Chronic cutaneous lupus erythematosus ": 25.003281218748143, "Circumstance or information capable of leading to medication error ": 42.14962042536585, "Condition aggravated ": 2.407857266631723, "Coronavirus infection ": 8.80104592298463, "Coronavirus test positive ": 25.31449839667781, "Cutaneous lupus erythematosus ": 18.58318381084857, "Cystitis ": 2.3083500739572926, "Decreased immune responsiveness ": 8.93098225373147, "Dengue fever ": 28.03295257333437, "Depression ": 2.1400587771739827, "Disability ": 2.911525200322367, "Discouragement ": 20.354368244169887, "Disease recurrence ": 2.3263480171405644, "Diverticulitis ": 2.693095472601253, "Drug effect less than expected ": 4.850461765358749, "Dysuria ": 2.4623047555874487, "Ear infection ": 3.191072336130972, "Emotional disorder ": 2.820879035883171, "Enteritis ": 2.0019553084667354, "Exposure via skin contact ": 92.24110670668782, "Eye infection ": 4.737690334207903, "Fibromyalgia ": 2.4156415864492544, "Functional gastrointestinal disorder ": 2.9791718978037025, "Gastroenteritis viral ": 3.293254720976102, "Gastrointestinal infection ": 4.824353772710448, "Herpes virus infection ": 3.657840266375231, "Hip arthroplasty ": 2.5896586722377584, "Hip surgery ": 3.567568354149594, "Hospitalisation ": 5.406711289728703, "Hysterectomy ": 7.131662929342876, "Ill-defined disorder ": 5.910832044256317, "Illness ": 4.429623282811039, "Immune system disorder ": 4.0110913209192605, "Immunodeficiency ": 6.030819616535878, "Immunosuppression ": 10.19676707680172, "Impaired gastric emptying ": 2.748325754845046, "Inappropriate schedule of product administration ": 6.838151745977968, "Infection ": 3.122456101302248, "Inflammation ": 3.025540944226234, "Influenza ": 2.990435487683974, "Injection site bruising ": 4.221267432906119, "Injection site haemorrhage ": 5.388953773604058, "Intervertebral disc protrusion ": 2.167926738944617, "JC virus infection ": 10.913633692233969, "Joint dislocation ": 3.1363259744576464, "Kidney infection ": 10.250514397730178, "Knee arthroplasty ": 3.369721812508712, "Knee operation ": 2.768289005750882, "Laboratory test abnormal ": 4.011493791593085, "Laryngeal oedema ": 2.2067016550619942, "Laryngitis ": 3.319218013145508, "Limb injury ": 4.100039900216026, "Limb operation ": 9.882498156932748, "Live birth ": 3.507425948673032, "Localised infection ": 4.7028537016138685, "Lung disorder ": 2.7979213404805585, "Lupus nephritis ": 167.11274984090224, "Lymphoma ": 2.2037318005382605, "Lymphopenia ": 2.593712939407104, "Meningitis ": 2.146702973141024, "Mental impairment ": 2.480285546723076, "Multiple allergies ": 4.533598841618911, "Nasal ulcer ": 20.443250103552167, "Nasopharyngitis ": 2.6154655047497246, "Nephritis ": 9.944140421621668, "Nephrolithiasis ": 3.1132338764932683, "Nervousness ": 2.2382170578450133, "Oral infection ": 7.128244385303307, "Oropharyngeal pain ": 2.5446083217043527, "Osteomyelitis ": 2.4460211871849213, "Painful respiration ": 2.9166157572853675, "Pancreatic enzymes increased ": 6.597701511130713, "Patient isolation ": 83.54886481302421, "Pharyngeal inflammation ": 15.603543282020508, "Pharyngitis ": 4.8021558954317936, "Pharyngitis streptococcal ": 6.261594681430518, "Pleurisy ": 8.128558707938724, "Pneumonia ": 2.927303455571056, "Pneumonia viral ": 4.156583469456789, "Polyarthritis ": 2.5309394579676234, "Post-traumatic stress disorder ": 3.158375253663774, "Procedural complication ": 5.727665115750488, "Product availability issue ": 25.63064723453765, "Product complaint ": 4.982124344830921, "Product dose omission issue ": 14.490609499865284, "Product storage error ": 2.0047198637834733, "Product supply issue ": 11.60850001699639, "Productive cough ": 3.219902346718569, "Progressive multifocal leukoencephalopathy ": 8.222367582116624, "Protein urine present ": 3.997195001964161, "Proteinuria ": 2.1200644818300947, "Pulmonary pain ": 2.634514958563839, "Pyelonephritis ": 2.23970263059006, "Quarantine ": 49.69031446954102, "Raynaud's phenomenon ": 2.549651254156743, "Renal disorder ": 2.4359538115030466, "Renal pain ": 2.015184507114773, "Respiratory tract infection ": 2.5195299821805874, "Rhinitis ": 2.836004513993525, "Rhinorrhoea ": 2.959161850835874, "SLE arthritis ": 53.664008332320535, "Secretion discharge ": 3.135167868643157, "Shoulder operation ": 6.981500190706231, "Sinus disorder ": 2.621254615195766, "Sinusitis ": 5.504484730404638, "Sjogren's syndrome ": 5.598950467182258, "Skin discolouration ": 2.563342710871376, "Skin disorder ": 3.2938905583168467, "Skin infection ": 3.23189915070601, "Skin laceration ": 2.3359975287312174, "Skin lesion ": 2.184004233537326, "Skin ulcer ": 3.059968733501684, "Sneezing ": 2.040137068363641, "Social problem ": 28.13200456572907, "Spinal disorder ": 2.8737229752042093, "Spinal operation ": 4.886626512723302, "Staphylococcal infection ": 3.388710284263295, "Stress ": 3.845896128641382, "Subcutaneous abscess ": 5.275554677179038, "Suicidal ideation ": 2.2477684798178448, "Surgery ": 6.626053796938585, "Symptom recurrence ": 7.714755378697043, "Systemic lupus erythematosus ": 50.11757263885596, "Systemic lupus erythematosus rash ": 19.345375212279126, "Therapeutic response shortened ": 3.0257997701899004, "Therapeutic response unexpected ": 3.927393154954128, "Therapy cessation ": 6.063781065209198, "Therapy interrupted ": 11.487210344146284, "Tooth abscess ": 4.632286961005069, "Tooth extraction ": 8.31033684750177, "Tooth infection ": 6.479566247594257, "Toothache ": 2.083339778994451, "Tuberculosis ": 2.179204434339044, "Underdose ": 7.377874063480426, "Upper respiratory tract infection ": 2.275161673522448, "Urinary tract infection ": 4.5750034085677305, "Urine abnormality ": 7.167127960484031, "Varicose vein ": 3.792892174522168, "Vasculitis ": 2.3096904202581925, "Vein disorder ": 6.861985047229591, "Vein rupture ": 12.766272162204825, "Viral infection ": 3.36515911267273, "Walking aid user ": 5.213523591683449, "Weight fluctuation ": 8.747155227774906, "Wound ": 3.1494979883392635, "Wound infection ": 2.7632341605416224, "Wrong technique in device usage process ": 13.667536751165205}
\ No newline at end of file
+{"Acne": 4.987092114352351, "Arthritis": 11.67689489268312, "Arthropathy": 5.827965804454518, "Blood cholesterol": 502.00280067980657, "Blood cholesterol abnormal": 60.07266253242842, "Blood pressure decreased": 8.32675741692458, "Blood pressure increased": 3.942828823399741, "Bronchitis": 4.369643278633794, "Calcinosis": 251.7007607167891, "Cystitis": 5.0608465792277615, "Diabetes mellitus": 2.205510694192626, "Diverticulitis": 4.885846385773479, "Gait disturbance": 2.386661837042828, "Gastrointestinal disorder": 2.654821217273124, "Hand deformity": 14.616996410922086, "Hypersomnia": 26.559866388981927, "Immune system disorder": 8.776419611016381, "Inflammation": 7.592193268642691, "Joint dislocation": 69.43455530613893, "Kidney infection": 49.62409140117257, "Loss of personal independence in daily activities": 9.13361982811423, "Lower respiratory tract infection": 5.316073800425885, "Migraine with aura": 18.825022305191485, "Multiple allergies": 91.81517002415158, "Nasopharyngitis": 5.546098095785391, "Nephrolithiasis": 21.242642033522174, "Personality change due to a general medical condition": 3441.48211353264, "Photophobia": 3.68058642349498, "Poor quality sleep": 17.64763999737211, "Product dose omission issue": 6.605336591084175, "Renal disorder": 16.595957887682637, "SLE arthritis": 2302.5150139179664, "Sinusitis": 3.493238138392944, "Skin induration": 120.83288024406104, "Skin lesion": 4.764061773365795, "Social problem": 85.62767969823344, "Spinal disorder": 58.04743129635512, "Systemic lupus erythematosus": 12.792718898788204, "Urinary tract infection": 2.1392731127664946, "Urine abnormality": 185.6437364662365, "Varicose vein": 90.30049662250867, "Vein disorder": 142.91539099639402, "Walking aid user": 127.29738705648506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/155.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/155.json
index d5081334fd0..9482fff908a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/155.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/155.json
@@ -1 +1 @@
-{"Asthma ": 32.93761781885751, "Bacterial disease carrier ": 1459.239819087143, "Bronchial obstruction ": 60.54757752079427, "Bronchial secretion retention ": 472.9529590113754, "Bronchial wall thickening ": 619.6235707617701, "Cardiac murmur ": 13.85179348447347, "Condition aggravated ": 4.475589521039869, "Cough ": 5.957791072319453, "Drug ineffective ": 2.335577464671426, "Dysarthria ": 3.1878529309639005, "Dyspnoea ": 4.9567023384589, "Dyspnoea exertional ": 2.163396984369974, "Eosinophil count increased ": 11.950311997483542, "Eosinophilic granulomatosis with polyangiitis ": 13.787285786964585, "Fall ": 3.683763555687933, "Full blood count abnormal ": 83.59629902439153, "Ill-defined disorder ": 16.699276260770333, "Infection ": 2.248190955785128, "Inflammation ": 3.125464878915571, "Intervertebral disc protrusion ": 64.67483208994119, "Loss of personal independence in daily activities ": 25.875353987394348, "Lung disorder ": 3.6909466127852175, "Lung opacity ": 15.764845244284697, "Muscle strain ": 28.12476520164093, "Musculoskeletal chest pain ": 8.428554414547074, "Mycobacterium avium complex infection ": 30.621198959091775, "Nasal congestion ": 5.706285634447246, "Nasopharyngitis ": 2.1134070196621866, "Obstructive airways disorder ": 62.91169907953648, "Pneumonia ": 2.0420835308353205, "Pneumonitis ": 5.124956793220637, "Productive cough ": 8.185417378578126, "Pseudomonas infection ": 81.75161960364622, "Pulmonary mass ": 6.782565840003742, "Rales ": 97.69847076294988, "Rhinovirus infection ": 93.0733056409477, "Secretion discharge ": 13.667022681993576, "Sense of oppression ": 35.4865654618466, "Septic shock ": 5.497043369485493, "Sleep disorder due to a general medical condition ": 97.8165103138532, "Slow speech ": 55.74648773929575, "Snoring ": 44.38388873104851, "Spinal cord compression ": 266.80019143419986, "Sputum discoloured ": 127.26802953674256, "Therapeutic product effect incomplete ": 34.028339758869535, "Upper limb fracture ": 71.24065781732918, "Wheezing ": 46.69890690254191, "Wrist fracture ": 79.50525212969944, "Wrong technique in product usage process ": 2.423575731257198}
\ No newline at end of file
+{"Abdominal pain lower": 79.10508326271024, "Ascites": 161.00914269102768, "Dyspnoea": 2.2846726162440403, "Ovarian hyperstimulation syndrome": 1748.431010687586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/156.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/156.json
index a54e0e51c06..3013a39b7fe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/156.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/156.json
@@ -1 +1 @@
-{"Accidental exposure to product ": 5.040554654149069, "Accidental overdose ": 5.519445121223284, "Agitation ": 2.5765772321480163, "Alcohol abuse ": 22.97173161425185, "Altered state of consciousness ": 3.078522396003399, "Apnoea ": 6.828105434603596, "Blood creatine phosphokinase increased ": 2.9166141255154985, "Bradypnoea ": 24.296804307395703, "Brain oedema ": 11.160649193841117, "Cardiac arrest ": 7.560098872954715, "Cardio-respiratory arrest ": 72.47240226216957, "Coma ": 10.88343757801302, "Completed suicide ": 61.5128329444677, "Death ": 5.4352271378574, "Depressed level of consciousness ": 3.036433457461556, "Drug abuse ": 50.48282359227272, "Drug dependence ": 9.552223164224207, "Drug detoxification ": 50.371841410850855, "Drug screen positive ": 135.42320396809225, "Drug withdrawal syndrome ": 9.57965703394802, "Drug withdrawal syndrome neonatal ": 31.410555451721237, "Electrocardiogram QT prolonged ": 4.489106397781578, "Foetal exposure during pregnancy ": 3.3808892362155145, "Hyperkalaemia ": 2.923089158744986, "Intentional overdose ": 13.518373231367365, "Intentional product misuse ": 13.86563142128302, "Intentional product use issue ": 3.349644179158676, "Miosis ": 11.58012151830402, "Overdose ": 13.28443762212147, "Pneumonia aspiration ": 8.895148900799963, "Poisoning ": 33.52905914479428, "Respiratory arrest ": 15.15325368812598, "Respiratory depression ": 8.277436106554003, "Rhabdomyolysis ": 7.114819133205719, "Substance abuse ": 46.285851496270766, "Substance use disorder ": 20.759470465012463, "Suicide attempt ": 5.833795972754047, "Suspected suicide ": 29.675945719772667, "Toxicity to various agents ": 26.654608788681, "Unresponsive to stimuli ": 4.995510704232264, "Withdrawal syndrome ": 5.511732148399275}
\ No newline at end of file
+{"Myalgia": 13.98203209107439}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/157.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/157.json
index 40e31ce9da8..a32c4a33707 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/157.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/157.json
@@ -1 +1 @@
-{"Accidental overdose ": 14.4873249797832, "Agitation ": 7.723144039330642, "Anisocoria ": 190.05902887406697, "Areflexia ": 95.37984249360052, "Ataxia ": 19.931863640616825, "Blood creatine phosphokinase increased ": 7.491816820058973, "Blood magnesium decreased ": 78.41658415073468, "Blood phosphorus decreased ": 130.45498989165938, "Blood potassium decreased ": 18.90217070148996, "Cardio-respiratory arrest ": 19.565107598877976, "Central nervous system lesion ": 69.14503867357573, "Completed suicide ": 23.4981743329371, "Death ": 2.720269185565836, "Drug abuse ": 21.311868883850032, "Drug dependence ": 4.937416434744581, "Drug screen positive ": 462.15194297836354, "Dyskinesia ": 29.36753253356509, "Electrocardiogram QT prolonged ": 8.43297277301866, "Electrolyte imbalance ": 39.838417985701255, "Focal dyscognitive seizures ": 129.36827053141727, "Foetal exposure during pregnancy ": 3.3457231214169907, "Hypotension ": 3.061489714944795, "Intentional overdose ": 5.675225325817674, "Intentional product misuse ": 5.774684714109031, "Loss of consciousness ": 2.279977767315066, "Mental impairment ": 18.375343974002057, "Mental status changes ": 28.02188055093436, "Movement disorder ": 13.086613918213608, "Muscular weakness ": 7.167479031125765, "Overdose ": 11.273215314666494, "Paraparesis ": 122.0268062117308, "Somnolence ": 2.2169361162525343, "Substance abuse ": 86.0903870279452, "Suicide attempt ": 5.9510149231212095, "Torsade de pointes ": 36.4015154773553, "Toxicity to various agents ": 6.998741173808761, "Ventricular arrhythmia ": 105.43338101016818}
\ No newline at end of file
+{"Arthralgia": 2.54344143421652, "Chills": 2.244704786630261, "Injection site inflammation": 7.418102639341672, "Injection site pain": 3.709513560605971, "Malaise": 2.785766211022064, "Myalgia": 2.006576742129483}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/158.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/158.json
index 178a510d79b..3517fd26d52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/158.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/158.json
@@ -1 +1 @@
-{"Anterior chamber cell ": 1357.3753331681553, "Anterior chamber flare ": 1576.6926865036194, "Anterior chamber inflammation ": 451.4766247129453, "Arteritis ": 93.67428826407624, "Blindness ": 35.17948017097839, "Blindness transient ": 44.23872226447951, "Blindness unilateral ": 24.55406213144068, "Cataract ": 4.149969651199775, "Chorioretinitis ": 471.1826648627459, "Choroidal neovascularisation ": 360.2528882273764, "Conjunctival hyperaemia ": 12.886013369570108, "Corneal disorder ": 29.88471962685086, "Corneal oedema ": 45.77809101844687, "Deformity ": 7.856880717763529, "Detachment of retinal pigment epithelium ": 410.9126513395976, "Dry eye ": 2.451368120452899, "Endophthalmitis ": 64.95328821927362, "Eye haemorrhage ": 9.11409884699867, "Eye inflammation ": 327.8943497620763, "Eye injury ": 21.658271422350285, "Eye irritation ": 15.833640763139837, "Eye oedema ": 17.22268823265324, "Eye pain ": 25.685321557989138, "Foreign body sensation in eyes ": 26.226150408941898, "Glaucoma ": 4.8270793968633, "Hypopyon ": 73.94804861967218, "Intra-ocular injection complication ": 392.3353624342832, "Intraocular pressure increased ": 56.8493830803552, "Iridocyclitis ": 719.8298957214732, "Iritis ": 289.3688999601866, "Keratic precipitates ": 1156.887711329971, "Lacrimation increased ": 4.228847533318706, "Macular degeneration ": 2.753031074251332, "Macular oedema ": 56.81511750917128, "Metamorphopsia ": 33.85487800279317, "Neovascular age-related macular degeneration ": 73.56496946099988, "Non-infectious endophthalmitis ": 106.17963605536713, "Ocular discomfort ": 18.85339119830556, "Ocular hyperaemia ": 37.57471454772128, "Ocular vasculitis ": 577.9275414880514, "Papilloedema ": 17.215404632937354, "Photophobia ": 5.086577637595925, "Photopsia ": 17.3774057964473, "Retinal artery occlusion ": 226.58917402096003, "Retinal degeneration ": 96.41387334931284, "Retinal disorder ": 26.523705641859674, "Retinal drusen ": 293.47867579839766, "Retinal exudates ": 101.652823916932, "Retinal haemorrhage ": 56.89751892785781, "Retinal ischaemia ": 384.2242388195816, "Retinal occlusive vasculitis ": 3097.1492635585246, "Retinal oedema ": 208.7182510189823, "Retinal perivascular sheathing ": 505.3975975475827, "Retinal pigment epithelial tear ": 154.33354710152312, "Retinal vascular occlusion ": 1085.3663207639063, "Retinal vasculitis ": 1958.8201216085724, "Retinal vein occlusion ": 38.83457347859932, "Subretinal fluid ": 388.3549573386, "Uveitis ": 310.5659431194356, "Vasculitis ": 8.92847517185919, "Vision blurred ": 23.60616258017804, "Visual acuity reduced ": 148.50758408819283, "Visual field defect ": 17.971020566661668, "Visual impairment ": 15.303544586473242, "Vitreal cells ": 1187.2914145958564, "Vitreous detachment ": 48.30570463289322, "Vitreous disorder ": 202.60103771510336, "Vitreous floaters ": 461.0423291570274, "Vitreous haemorrhage ": 33.94671956050921, "Vitreous opacities ": 576.5055252585477, "Vitritis ": 1901.024326727793}
\ No newline at end of file
+{"Accidental exposure to product": 3.4356332218278096, "Adverse drug reaction": 3.0537326151522164, "Antiphospholipid syndrome": 6.886619903555781, "Arthritis": 2.818988549588164, "Bacterial infection": 2.736413516238663, "Bedridden": 2.5178329136492925, "Blood cholesterol abnormal": 3.3069041875687133, "Blood test abnormal": 2.617379042781179, "Brain fog": 2.1332784180768622, "Bronchitis": 3.954808607860557, "Butterfly rash": 28.126996441217948, "Calcinosis": 7.49986041760068, "Cardiac operation": 2.7978749982041404, "Cataract operation": 3.2524693257018487, "Catarrh": 4.284805757933276, "Cellulitis": 2.804685630571506, "Central nervous system lupus": 133.52816334255775, "Cerebrospinal fluid leakage": 8.243432857888605, "Cholecystectomy": 2.596454991117624, "Chronic cutaneous lupus erythematosus": 25.003281218748143, "Circumstance or information capable of leading to medication error": 42.14962042536585, "Condition aggravated": 2.407857266631723, "Coronavirus infection": 8.80104592298463, "Coronavirus test positive": 25.31449839667781, "Cutaneous lupus erythematosus": 18.58318381084857, "Cystitis": 2.3083500739572926, "Decreased immune responsiveness": 8.93098225373147, "Dengue fever": 28.03295257333437, "Depression": 2.1400587771739827, "Disability": 2.911525200322367, "Discouragement": 20.354368244169887, "Disease recurrence": 2.3263480171405644, "Diverticulitis": 2.693095472601253, "Drug effect less than expected": 4.850461765358749, "Dysuria": 2.4623047555874487, "Ear infection": 3.191072336130972, "Emotional disorder": 2.820879035883171, "Enteritis": 2.0019553084667354, "Exposure via skin contact": 92.24110670668782, "Eye infection": 4.737690334207903, "Fibromyalgia": 2.4156415864492544, "Functional gastrointestinal disorder": 2.9791718978037025, "Gastroenteritis viral": 3.293254720976102, "Gastrointestinal infection": 4.824353772710448, "Herpes virus infection": 3.657840266375231, "Hip arthroplasty": 2.5896586722377584, "Hip surgery": 3.567568354149594, "Hospitalisation": 5.406711289728703, "Hysterectomy": 7.131662929342876, "Ill-defined disorder": 5.910832044256317, "Illness": 4.429623282811039, "Immune system disorder": 4.0110913209192605, "Immunodeficiency": 6.030819616535878, "Immunosuppression": 10.19676707680172, "Impaired gastric emptying": 2.748325754845046, "Inappropriate schedule of product administration": 6.838151745977968, "Infection": 3.122456101302248, "Inflammation": 3.0253871733748467, "Influenza": 2.990435487683974, "Injection site bruising": 4.221267432906119, "Injection site haemorrhage": 5.388953773604058, "Intervertebral disc protrusion": 2.167926738944617, "JC virus infection": 10.913633692233969, "Joint dislocation": 3.1363259744576464, "Kidney infection": 10.250514397730178, "Knee arthroplasty": 3.369721812508712, "Knee operation": 2.768289005750882, "Laboratory test abnormal": 4.011493791593085, "Laryngeal oedema": 2.2067016550619942, "Laryngitis": 3.319218013145508, "Limb injury": 4.100039900216026, "Limb operation": 9.882498156932748, "Live birth": 3.507425948673032, "Localised infection": 4.7028537016138685, "Lung disorder": 2.7979213404805585, "Lupus nephritis": 167.11274984090224, "Lymphoma": 2.2037318005382605, "Lymphopenia": 2.593712939407104, "Meningitis": 2.146702973141024, "Mental impairment": 2.480285546723076, "Multiple allergies": 4.533598841618911, "Nasal ulcer": 20.443250103552167, "Nasopharyngitis": 2.615265537480888, "Nephritis": 9.944140421621668, "Nephrolithiasis": 3.112717149961753, "Nervousness": 2.2382170578450133, "Oral infection": 7.128244385303307, "Oropharyngeal pain": 2.5446083217043527, "Osteomyelitis": 2.4460211871849213, "Painful respiration": 2.9166157572853675, "Pancreatic enzymes increased": 6.597701511130713, "Patient isolation": 83.54886481302421, "Pharyngeal inflammation": 15.603543282020508, "Pharyngitis": 4.80104222973927, "Pharyngitis streptococcal": 6.261594681430518, "Pleurisy": 8.128558707938724, "Pneumonia": 2.927303455571056, "Pneumonia viral": 4.156583469456789, "Polyarthritis": 2.5309394579676234, "Post-traumatic stress disorder": 3.158375253663774, "Procedural complication": 5.727665115750488, "Product availability issue": 25.63064723453765, "Product complaint": 4.982124344830921, "Product dose omission issue": 14.490609499865284, "Product storage error": 2.0047198637834733, "Product supply issue": 11.60850001699639, "Productive cough": 3.219902346718569, "Progressive multifocal leukoencephalopathy": 8.222367582116624, "Protein urine present": 3.997195001964161, "Proteinuria": 2.1200644818300947, "Pulmonary pain": 2.634514958563839, "Pyelonephritis": 2.23970263059006, "Quarantine": 49.69031446954102, "Raynaud's phenomenon": 2.549651254156743, "Renal disorder": 2.435593367157548, "Renal pain": 2.015184507114773, "Respiratory tract infection": 2.5195299821805874, "Rhinitis": 2.836004513993525, "Rhinorrhoea": 2.959161850835874, "SLE arthritis": 53.664008332320535, "Secretion discharge": 3.135167868643157, "Shoulder operation": 6.981500190706231, "Sinus disorder": 2.621254615195766, "Sinusitis": 5.504484730404638, "Sjogren's syndrome": 5.598950467182258, "Skin discolouration": 2.563342710871376, "Skin disorder": 3.2938905583168467, "Skin infection": 3.23189915070601, "Skin laceration": 2.3359975287312174, "Skin lesion": 2.184004233537326, "Skin ulcer": 3.059968733501684, "Sneezing": 2.040137068363641, "Social problem": 28.13200456572907, "Spinal disorder": 2.8737229752042093, "Spinal operation": 4.886626512723302, "Staphylococcal infection": 3.388710284263295, "Stress": 3.845896128641382, "Subcutaneous abscess": 5.275554677179038, "Suicidal ideation": 2.2477684798178448, "Surgery": 6.626053796938585, "Symptom recurrence": 7.714755378697043, "Systemic lupus erythematosus": 50.11757263885596, "Systemic lupus erythematosus rash": 19.345375212279126, "Therapeutic response shortened": 3.0257997701899004, "Therapeutic response unexpected": 3.927393154954128, "Therapy cessation": 6.063781065209198, "Therapy interrupted": 11.487210344146284, "Tooth abscess": 4.632286961005069, "Tooth extraction": 8.31033684750177, "Tooth infection": 6.479566247594257, "Toothache": 2.083339778994451, "Tuberculosis": 2.179204434339044, "Underdose": 7.377874063480426, "Upper respiratory tract infection": 2.275161673522448, "Urinary tract infection": 4.5750034085677305, "Urine abnormality": 7.167127960484031, "Varicose vein": 3.792892174522168, "Vasculitis": 2.3096904202581925, "Vein disorder": 6.861985047229591, "Vein rupture": 12.766272162204825, "Viral infection": 3.36515911267273, "Walking aid user": 5.213523591683449, "Weight fluctuation": 8.747155227774906, "Wound": 3.149208206629555, "Wound infection": 2.7632341605416224, "Wrong technique in device usage process": 13.667536751165205}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/159.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/159.json
index b3acb1227da..d9f005f9b90 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/159.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/159.json
@@ -1 +1 @@
-{"Venoocclusive liver disease ": 845.8717975460762}
\ No newline at end of file
+{"Asthma": 32.83479531709306, "Bacterial disease carrier": 1450.1922535385702, "Bronchial obstruction": 60.17241970052928, "Bronchial secretion retention": 470.02037421264754, "Bronchial wall thickening": 615.7814374115536, "Cardiac murmur": 13.765966130155894, "Condition aggravated": 4.447827427697767, "Cough": 5.967008988577521, "Drug ineffective": 2.321064574388682, "Dysarthria": 3.1681000635322896, "Dyspnoea": 4.944854100459206, "Dyspnoea exertional": 2.149993865559562, "Eosinophil count increased": 11.87626445710108, "Eosinophilic granulomatosis with polyangiitis": 13.701868092712829, "Fall": 3.660823778617478, "Full blood count abnormal": 83.07725265669586, "Ill-defined disorder": 16.595726808467234, "Infection": 2.2342581759198588, "Inflammation": 3.1059403214309613, "Intervertebral disc protrusion": 64.2737592316961, "Loss of personal independence in daily activities": 25.913428586370937, "Lung disorder": 3.668075840188554, "Lung opacity": 15.667178966294692, "Muscle strain": 27.95050112906589, "Musculoskeletal chest pain": 8.3763300573528, "Mycobacterium avium complex infection": 30.431495001495907, "Nasal congestion": 5.670922704022179, "Nasopharyngitis": 2.100149486784273, "Obstructive airways disorder": 62.52144015713724, "Pneumonia": 2.076725458747652, "Pneumonitis": 5.0932010724753685, "Productive cough": 8.13468241454297, "Pseudomonas infection": 81.24480450677787, "Pulmonary mass": 6.740545125336133, "Rales": 97.09260983396833, "Rhinovirus infection": 92.49649448687278, "Secretion discharge": 13.582347447204342, "Sense of oppression": 35.266687081121624, "Septic shock": 5.4629795260683, "Sleep disorder due to a general medical condition": 97.20943505285862, "Slow speech": 55.40107766821069, "Snoring": 44.10888192705847, "Spinal cord compression": 265.1457268323928, "Sputum discoloured": 126.47872099501672, "Therapeutic product effect incomplete": 33.81704893569509, "Upper limb fracture": 70.79886837946053, "Wheezing": 46.61295754297871, "Wrist fracture": 79.0122051594238, "Wrong technique in product usage process": 2.408558947536545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/16.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/16.json
index c6d48c01f7e..d999abbbea4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/16.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/16.json
@@ -1 +1 @@
-{"Drug ineffective ": 23.07043989973285, "Macular degeneration ": 2094.342912544314}
\ No newline at end of file
+{"Depression": 4.811151319976349, "Drug dependence": 197.37695047392972, "Emotional distress": 11.540852615818826, "Overdose": 11.59275491568321, "Suicidal ideation": 8.057830598170321}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/160.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/160.json
index a9eced0f8f9..a06fa1ddce2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/160.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/160.json
@@ -1 +1 @@
-{"Influenza like illness ": 4.603300738466763, "Off label use ": 4.56679690509033, "Pruritus ": 5.596282910433106}
\ No newline at end of file
+{"Accidental exposure to product": 5.040554654149069, "Accidental overdose": 5.519445121223284, "Agitation": 2.5765772321480163, "Alcohol abuse": 22.97173161425185, "Altered state of consciousness": 3.078522396003399, "Apnoea": 6.828105434603596, "Blood creatine phosphokinase increased": 2.9166141255154985, "Bradypnoea": 24.296804307395703, "Brain oedema": 11.160649193841117, "Cardiac arrest": 7.560098872954715, "Cardio-respiratory arrest": 72.47240226216957, "Coma": 10.88343757801302, "Completed suicide": 61.5128329444677, "Death": 5.4352271378574, "Depressed level of consciousness": 3.036433457461556, "Drug abuse": 50.48282359227272, "Drug dependence": 9.552223164224207, "Drug detoxification": 50.371841410850855, "Drug screen positive": 135.42320396809225, "Drug withdrawal syndrome": 9.57965703394802, "Drug withdrawal syndrome neonatal": 31.410555451721237, "Electrocardiogram QT prolonged": 4.489106397781578, "Foetal exposure during pregnancy": 3.3808892362155145, "Hyperkalaemia": 2.922686086115226, "Intentional overdose": 13.518373231367365, "Intentional product misuse": 13.86563142128302, "Intentional product use issue": 3.349644179158676, "Miosis": 11.58012151830402, "Overdose": 13.28443762212147, "Pneumonia aspiration": 8.895148900799963, "Poisoning": 33.52905914479428, "Respiratory arrest": 15.15325368812598, "Respiratory depression": 8.277436106554003, "Rhabdomyolysis": 7.114819133205719, "Substance abuse": 46.285851496270766, "Substance use disorder": 20.759470465012463, "Suicide attempt": 5.833795972754047, "Suspected suicide": 29.675945719772667, "Toxicity to various agents": 26.654608788681, "Unresponsive to stimuli": 4.994961236051715, "Withdrawal syndrome": 5.511732148399275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/161.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/161.json
index 0ae51cf9dcc..b82db291542 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/161.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/161.json
@@ -1 +1 @@
-{"Bradycardia ": 9.180797974562536, "Completed suicide ": 108.4257044897281, "Drug interaction ": 2.6753680037548326, "Intentional overdose ": 8.088083989614736, "Suicide attempt ": 6.692608583967592, "Syncope ": 2.87167496675773, "Toxicity to various agents ": 26.78575417321673}
\ No newline at end of file
+{"Accidental overdose": 14.4873249797832, "Agitation": 7.723144039330642, "Anisocoria": 190.05902887406697, "Areflexia": 95.37984249360052, "Ataxia": 19.931863640616825, "Blood creatine phosphokinase increased": 7.491816820058973, "Blood magnesium decreased": 78.41658415073468, "Blood phosphorus decreased": 130.45498989165938, "Blood potassium decreased": 18.90217070148996, "Cardio-respiratory arrest": 19.565107598877976, "Central nervous system lesion": 69.14503867357573, "Completed suicide": 23.4981743329371, "Death": 2.720269185565836, "Drug abuse": 21.311868883850032, "Drug dependence": 4.937416434744581, "Drug screen positive": 462.15194297836354, "Dyskinesia": 29.36753253356509, "Electrocardiogram QT prolonged": 8.43297277301866, "Electrolyte imbalance": 39.838417985701255, "Focal dyscognitive seizures": 129.36827053141727, "Foetal exposure during pregnancy": 3.3457231214169907, "Hypotension": 3.0614189392162388, "Intentional overdose": 5.675225325817674, "Intentional product misuse": 5.774684714109031, "Loss of consciousness": 2.279866197690245, "Mental impairment": 18.375343974002057, "Mental status changes": 28.02188055093436, "Movement disorder": 13.086613918213608, "Muscular weakness": 7.167479031125765, "Overdose": 11.273215314666494, "Paraparesis": 122.0268062117308, "Somnolence": 2.216911679650051, "Substance abuse": 86.0903870279452, "Suicide attempt": 5.9510149231212095, "Torsade de pointes": 36.4015154773553, "Toxicity to various agents": 6.998741173808761, "Ventricular arrhythmia": 105.43338101016818}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/162.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/162.json
index 275bab19906..37cdebcdbe3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/162.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/162.json
@@ -1 +1 @@
-{"Completed suicide ": 69.70506869533357}
\ No newline at end of file
+{"Anterior chamber cell": 1357.3753331681553, "Anterior chamber flare": 1576.6926865036194, "Anterior chamber inflammation": 451.4766247129453, "Arteritis": 93.67428826407624, "Blindness": 35.17948017097839, "Blindness transient": 44.23872226447951, "Blindness unilateral": 24.55406213144068, "Cataract": 4.149969651199775, "Chorioretinitis": 471.1826648627459, "Choroidal neovascularisation": 360.2528882273764, "Conjunctival hyperaemia": 12.886013369570108, "Corneal disorder": 29.88471962685086, "Corneal oedema": 45.77809101844687, "Deformity": 7.856880717763529, "Detachment of retinal pigment epithelium": 410.9126513395976, "Dry eye": 2.451368120452899, "Endophthalmitis": 64.95328821927362, "Eye haemorrhage": 9.11409884699867, "Eye inflammation": 327.8943497620763, "Eye injury": 21.658271422350285, "Eye irritation": 15.833640763139837, "Eye oedema": 17.22268823265324, "Eye pain": 25.685321557989138, "Foreign body sensation in eyes": 26.226150408941898, "Glaucoma": 4.8270793968633, "Hypopyon": 73.94804861967218, "Intra-ocular injection complication": 392.3353624342832, "Intraocular pressure increased": 56.8493830803552, "Iridocyclitis": 719.8298957214732, "Iritis": 289.3688999601866, "Keratic precipitates": 1156.887711329971, "Lacrimation increased": 4.228847533318706, "Macular degeneration": 2.753031074251332, "Macular oedema": 56.81511750917128, "Metamorphopsia": 33.85487800279317, "Neovascular age-related macular degeneration": 73.56496946099988, "Non-infectious endophthalmitis": 106.17963605536713, "Ocular discomfort": 18.85339119830556, "Ocular hyperaemia": 37.57471454772128, "Ocular vasculitis": 577.9275414880514, "Papilloedema": 17.215404632937354, "Photophobia": 5.0861089066018605, "Photopsia": 17.3774057964473, "Retinal artery occlusion": 226.58917402096003, "Retinal degeneration": 96.41387334931284, "Retinal disorder": 26.523705641859674, "Retinal drusen": 293.47867579839766, "Retinal exudates": 101.652823916932, "Retinal haemorrhage": 56.89751892785781, "Retinal ischaemia": 384.2242388195816, "Retinal occlusive vasculitis": 3097.1492635585246, "Retinal oedema": 208.7182510189823, "Retinal perivascular sheathing": 505.3975975475827, "Retinal pigment epithelial tear": 154.33354710152312, "Retinal vascular occlusion": 1085.3663207639063, "Retinal vasculitis": 1958.8201216085724, "Retinal vein occlusion": 38.83457347859932, "Subretinal fluid": 388.3549573386, "Uveitis": 310.5659431194356, "Vasculitis": 8.92847517185919, "Vision blurred": 23.60616258017804, "Visual acuity reduced": 148.50758408819283, "Visual field defect": 17.971020566661668, "Visual impairment": 15.303544586473242, "Vitreal cells": 1187.2914145958564, "Vitreous detachment": 48.30570463289322, "Vitreous disorder": 202.60103771510336, "Vitreous floaters": 461.0423291570274, "Vitreous haemorrhage": 33.94671956050921, "Vitreous opacities": 576.5055252585477, "Vitritis": 1901.024326727793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/163.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/163.json
index cce16993556..f47db39ea5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/163.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/163.json
@@ -1 +1 @@
-{"Intentional overdose ": 80.7833639710511, "Suicide attempt ": 78.03396815773459, "Tachycardia ": 18.1461546350233}
\ No newline at end of file
+{"Venoocclusive liver disease": 845.8717975460762}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/164.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/164.json
index 075f944ab38..0e76ea5865b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/164.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/164.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.312950445121351, "Abscess ": 10.47828900988403, "Adverse event ": 2.0845571676533283, "Alanine aminotransferase increased ": 4.315551531010428, "Application site erythema ": 5.275672012420706, "Aspartate aminotransferase increased ": 4.192710698141751, "Ataxia ": 3.682963182425097, "Autoimmune hepatitis ": 11.16210432686378, "Autoimmune thyroiditis ": 6.594795665515045, "Breast cancer ": 2.9509869245289586, "Cardiomyopathy ": 4.149613964252412, "Cellulitis ": 4.31690922074272, "Depressed mood ": 2.510332754822995, "Depression ": 3.182238101549189, "Device operational issue ": 29.42985552102633, "Dilated cardiomyopathy ": 6.03127253524514, "Drug delivery system malfunction ": 9.141797321708395, "Erysipelas ": 5.753397019313024, "Expanded disability status scale score increased ": 263.1656190182535, "Gait disturbance ": 3.1365146214785318, "Gait inability ": 2.088595588605608, "Gamma-glutamyltransferase increased ": 8.029269148548016, "Hemiparesis ": 3.0333922882343907, "Hemiplegia ": 2.756704943379932, "Hepatic enzyme increased ": 2.4083389078484605, "Hepatic steatosis ": 3.333658828091606, "Hepatitis ": 3.45065821253789, "Hyperthyroidism ": 2.6736518743485163, "Incorrect dose administered by device ": 15.98675005858739, "Influenza like illness ": 5.200479261848722, "Injection site abscess ": 192.44242192436116, "Injection site atrophy ": 94.60407854944586, "Injection site bruising ": 8.995978415991233, "Injection site cellulitis ": 88.50121750688037, "Injection site discolouration ": 49.09361632465938, "Injection site erythema ": 6.455033157458272, "Injection site haematoma ": 3.429145212862429, "Injection site haemorrhage ": 7.617306709067428, "Injection site induration ": 19.87274297123187, "Injection site infection ": 69.9395905386055, "Injection site inflammation ": 3.108856076207028, "Injection site mass ": 14.03604619650286, "Injection site necrosis ": 242.46496516396616, "Injection site nodule ": 16.28219088088887, "Injection site oedema ": 5.978895877557384, "Injection site pain ": 3.4249191496727875, "Injection site rash ": 8.279254956593867, "Injection site reaction ": 11.620657051754536, "Injection site ulcer ": 150.39654939070428, "Jaundice ": 2.5575392497411418, "Leukopenia ": 2.845662841897447, "Liver function test increased ": 10.74301469681734, "Lymphocyte count decreased ": 6.762588910126118, "Lymphopenia ": 3.0272881448863496, "Mobility decreased ": 2.501567399333673, "Multiple sclerosis ": 69.19632833547284, "Multiple sclerosis relapse ": 83.12951191182691, "Muscle rigidity ": 2.472485330421788, "Muscle spasticity ": 12.430429347369362, "Muscular weakness ": 3.045618896583388, "Nephrotic syndrome ": 4.276446191708813, "Neuromyelitis optica spectrum disorder ": 36.07455045600889, "No adverse event ": 2.098320871672575, "Optic neuritis ": 15.885276611415652, "Panniculitis ": 13.03687385137447, "Paralysis ": 2.8328005403394143, "Paraparesis ": 13.538559077179602, "Product dose omission issue ": 3.6202939883059706, "Rash macular ": 2.0246893428786588, "Raynaud's phenomenon ": 6.364718809565585, "Secondary progressive multiple sclerosis ": 75.64917814063908, "Sensory disturbance ": 2.8814928679209904, "Skin necrosis ": 29.481193262851587, "Skin reaction ": 5.756386793338486, "Skin ulcer ": 2.697398202199367, "Thrombotic microangiopathy ": 10.124776492912403, "Transaminases increased ": 3.9777790598302936, "Urinary incontinence ": 2.035830871649755}
\ No newline at end of file
+{"Influenza like illness": 4.603300738466763, "Off label use": 4.566617043440687, "Pruritus": 5.596215127439646}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/165.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/165.json
index eee5d3e0883..095339ca932 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/165.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/165.json
@@ -1 +1 @@
-{"Arrhythmia ": 4.803171294325519, "Atrial fibrillation ": 8.62945311230828, "Bladder pain ": 40.77052339943651, "Blood pressure increased ": 13.212802497626155, "Blood pressure systolic increased ": 7.600927591689569, "Blood urine present ": 6.610177408113944, "Constipation ": 7.540772653140951, "Cystitis ": 9.102223441629466, "Dizziness ": 2.0706440640635884, "Drug ineffective for unapproved indication ": 4.61108210231941, "Drug interaction ": 4.181480808333663, "Dry eye ": 6.721857575798488, "Dry mouth ": 11.685931224457336, "Dry throat ": 5.28052200494966, "Dyspepsia ": 2.592440165742671, "Dysuria ": 14.081119804603617, "Erectile dysfunction ": 3.740623297324343, "Eye swelling ": 3.440645511527012, "Eyelid oedema ": 7.685191081438687, "Flatulence ": 2.274305979639096, "Gastritis ": 2.879069385533123, "Glaucoma ": 3.0240552842945814, "Heart rate increased ": 2.699753889760992, "Heart rate irregular ": 3.0533519580028323, "Hypertension ": 6.695449284075036, "Hypertensive crisis ": 14.94899623366564, "Hypertonic bladder ": 25.58645950238521, "Inappropriate schedule of product administration ": 2.651116169060718, "Incontinence ": 4.789270373588477, "Intentional product misuse ": 2.4986282477666037, "Joint swelling ": 2.239649734535078, "Micturition urgency ": 16.102872177207068, "Mouth swelling ": 3.7193403503664033, "Nightmare ": 2.382205075119483, "Nocturia ": 28.62102145270435, "Oedema peripheral ": 2.130477826037653, "Palpitations ": 5.7441885439448175, "Petechiae ": 2.477451035451456, "Pollakiuria ": 14.005895435295397, "Product availability issue ": 7.985409058127021, "Product use in unapproved indication ": 3.3020931503657627, "Purpura ": 2.520140639626995, "Swelling of eyelid ": 7.483972351985338, "Swollen tongue ": 2.2244958654832154, "Tachycardia ": 4.85338060999789, "Therapeutic product effect incomplete ": 2.971112277528776, "Urinary hesitation ": 17.972295595713625, "Urinary incontinence ": 13.598836000635425, "Urinary retention ": 43.47283709846098, "Urinary tract infection ": 6.375076444038133, "Urine flow decreased ": 24.517146887549977, "Urine odour abnormal ": 12.27151118323859, "Vulvovaginal pruritus ": 22.8773739055385, "Wrong technique in product usage process ": 5.946208146776063}
\ No newline at end of file
+{"Bradycardia": 9.180510270570847, "Completed suicide": 108.4257044897281, "Drug interaction": 2.6753680037548326, "Intentional overdose": 8.088083989614736, "Suicide attempt": 6.692608583967592, "Syncope": 2.8716354490867846, "Toxicity to various agents": 26.78575417321673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/166.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/166.json
index 8e133007cbf..80a5de4fcae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/166.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/166.json
@@ -1 +1 @@
-{"Abdominal abscess ": 6.029422655673468, "Abscess ": 2.243181028513752, "Acquired gene mutation ": 12.322723808550412, "Acute abdomen ": 9.442356420260865, "Acute myeloid leukaemia ": 3.299038200365937, "Adenocarcinoma ": 9.86493757326402, "Adenocarcinoma of colon ": 30.191752592329667, "Anaemia ": 2.544306238932652, "Anastomotic leak ": 79.46785122459488, "Ascites ": 4.268068885608932, "Astrocytoma, low grade ": 81.06149364194692, "Autoimmune haemolytic anaemia ": 2.5829495728601635, "Bacteraemia ": 5.805863403967593, "Blindness ": 2.899225985783082, "Blood albumin decreased ": 4.0883085805486585, "Blood pressure diastolic increased ": 19.40030522254752, "Body temperature decreased ": 7.178577943965769, "Bone marrow disorder ": 25.096949235623903, "Bone marrow failure ": 3.153405917250005, "Breast cancer metastatic ": 2.2729636564145133, "Candida infection ": 4.321454184568975, "Carcinoembryonic antigen increased ": 20.637707371921536, "Cardiotoxicity ": 4.407805301191615, "Colitis ischaemic ": 2.152128726708425, "Colon cancer ": 3.24419308437258, "Colon cancer metastatic ": 49.15886405196682, "Colorectal cancer metastatic ": 122.36531925249588, "Coma scale abnormal ": 10.007763600369694, "Deep vein thrombosis ": 2.5416181255160417, "Dehydration ": 2.116388736820449, "Dermatitis acneiform ": 7.312747425755135, "Diarrhoea ": 2.963101034397626, "Disease progression ": 17.303590059802296, "Disease recurrence ": 2.9980416068610043, "Drug resistance ": 4.207966585288656, "Eastern Cooperative Oncology Group performance status worsened ": 32.31847267070204, "Ejection fraction decreased ": 2.343671456373107, "Embolism ": 5.387428116240368, "Embolism venous ": 7.7124713056717935, "Enteritis ": 4.482447271367416, "Enterocolitis ": 2.446079362534105, "Epistaxis ": 5.9371275112743325, "Febrile neutropenia ": 7.777786918692331, "Fistula ": 4.166772384721566, "Fournier's gangrene ": 6.003617912462157, "Gastrointestinal disorder ": 2.668493146814696, "Gastrointestinal haemorrhage ": 2.088693443626908, "Gastrointestinal motility disorder ": 3.715715134583625, "Gastrointestinal necrosis ": 8.304550847446531, "Gastrointestinal perforation ": 21.148462020263786, "Gastrointestinal toxicity ": 20.520141478351864, "Gene mutation ": 13.123366378641212, "Glioblastoma ": 12.391755044734383, "Granulocyte count decreased ": 7.388076152621527, "Haematocrit decreased ": 2.7721037922102703, "Haematotoxicity ": 25.053561642717888, "Haemoglobin abnormal ": 3.68249565625138, "Haemoglobin decreased ": 2.438118996756441, "Haemoptysis ": 2.456775051238413, "Hemiparesis ": 3.586357284777744, "Hepatic failure ": 2.0145230023383824, "Hepatic steatosis ": 2.275603479062707, "Hepatitis B reactivation ": 12.350542085568891, "Hiccups ": 7.797453592364011, "Hydronephrosis ": 2.4075860870194914, "Hyperammonaemia ": 2.092531567619367, "Hyperammonaemic encephalopathy ": 7.967767992182752, "Hyperbilirubinaemia ": 3.19566443575081, "Hypertension ": 4.434333862466667, "Hypoalbuminaemia ": 3.7346876644465583, "Hypomagnesaemia ": 6.844847831025537, "Hypophosphataemia ": 2.0769990626770545, "Ileus ": 6.410873255619391, "Immune-mediated hepatitis ": 4.86306683018024, "Incoherent ": 10.905387006102924, "Interstitial lung disease ": 2.3784154819380974, "Intestinal obstruction ": 3.333086100123297, "Intestinal perforation ": 11.948464949107269, "Invasive ductal breast carcinoma ": 5.514887515241198, "Large intestinal obstruction ": 15.071988428443808, "Large intestine perforation ": 22.42168051045469, "Left ventricular dysfunction ": 6.381683760872453, "Leukoencephalopathy ": 3.8912272912641073, "Leukopenia ": 4.698945038600277, "Lower gastrointestinal haemorrhage ": 2.848027467709434, "Lung adenocarcinoma ": 6.667700423761304, "Lung infiltration ": 2.1242273120263704, "Lymphangiosis carcinomatosa ": 15.943838724100871, "Lymphocyte count decreased ": 5.269658418720744, "Magnetic resonance imaging head abnormal ": 13.292326543312454, "Malignant neoplasm progression ": 8.337986541308332, "Mean cell volume increased ": 12.530608336139084, "Mental status changes ": 3.035248812880296, "Metastases to bone ": 7.602820045694378, "Metastases to bone marrow ": 31.53780885532417, "Metastases to central nervous system ": 8.111974753966239, "Metastases to liver ": 21.05723344247512, "Metastases to lung ": 17.951351519640106, "Metastases to lymph nodes ": 11.984289094093535, "Metastases to ovary ": 56.69051435988442, "Metastases to peritoneum ": 19.64027420307878, "Metastases to pleura ": 20.34230163395972, "Metastases to spine ": 7.493469205097857, "Metastasis ": 2.629886995062024, "Metastatic neoplasm ": 9.884736656037571, "Mouth ulceration ": 2.341912820587715, "Mucosal inflammation ": 9.19484483244863, "Multiple-drug resistance ": 2.822592450768702, "Myelodysplastic syndrome ": 2.63914603567144, "Myelosuppression ": 18.740888338968787, "Neoplasm ": 2.370744962383161, "Neoplasm progression ": 13.513197012277514, "Nephrotic syndrome ": 6.04845066741208, "Nerve injury ": 5.370427662085597, "Nervous system disorder ": 3.117851772203976, "Neuropathy peripheral ": 12.239002960030714, "Neurotoxicity ": 20.21455008908868, "Neutropenia ": 9.664512777770453, "Neutropenic sepsis ": 5.831359160009026, "Neutrophil count abnormal ": 10.35443142948545, "Neutrophil count decreased ": 11.539587025986638, "Neutrophil count increased ": 4.924103356753341, "Non-small cell lung cancer ": 6.249356195065518, "Oesophagitis ": 4.111529694515274, "Osteonecrosis of jaw ": 4.929753772125436, "Ovarian cancer ": 5.372149505499167, "Palmar-plantar erythrodysaesthesia syndrome ": 8.156149730935889, "Paraneoplastic syndrome ": 32.90743054345186, "Paronychia ": 16.433894527846267, "Performance status decreased ": 2.892702846091133, "Peripheral sensory neuropathy ": 9.75463611979253, "Peritonitis ": 3.871864109144701, "Pigmentation disorder ": 3.023676281123968, "Platelet count decreased ": 3.52797003831426, "Pleural effusion ": 2.018593796112311, "Pneumocystis jirovecii pneumonia ": 3.234417694715552, "Pneumonitis ": 3.0566644517396244, "Polyneuropathy ": 3.3054588069212545, "Portal hypertension ": 16.905831135172203, "Portal vein thrombosis ": 8.682007320946147, "Posterior reversible encephalopathy syndrome ": 16.037488480954025, "Protein urine present ": 6.153686575012781, "Proteinuria ": 15.406635104997276, "Pseudocirrhosis ": 128.3624554030931, "Pulmonary artery thrombosis ": 26.998085716158297, "Pulmonary embolism ": 2.522776190224362, "Pulmonary toxicity ": 4.831504052308411, "Rectal adenocarcinoma ": 47.93257665093618, "Rectal cancer ": 6.517178790351814, "Rectal haemorrhage ": 2.9698872103896083, "Red blood cell count decreased ": 2.50550337315122, "Scleral thinning ": 224.95115979740183, "Second primary malignancy ": 2.515316780227105, "Septic shock ": 2.5083269637545187, "Skin hyperpigmentation ": 2.801901253308261, "Skin toxicity ": 17.51386657213315, "Small intestinal obstruction ": 5.27996869781104, "Small intestinal perforation ": 11.586536902182903, "Splenomegaly ": 3.538136184408017, "Stoma site haemorrhage ": 37.741938975966605, "Stomatitis ": 3.557000017307568, "Subretinal fluid ": 16.728730146852527, "Systemic candida ": 7.633130533655028, "Temperature intolerance ": 2.58504977342049, "Therapy non-responder ": 3.0047148341076952, "Therapy partial responder ": 15.221348171998528, "Thrombocytopenia ": 4.762123677625729, "Thrombocytopenic purpura ": 4.079120258028757, "Thrombotic microangiopathy ": 4.171632426132098, "Treatment failure ": 2.132631690154196, "Tumour lysis syndrome ": 3.112194799622257, "Tumour marker increased ": 5.829688411666147, "Tumour necrosis ": 59.87721328503066, "Vascular device infection ": 3.7105654893141375, "Venoocclusive liver disease ": 3.338730302163613, "White blood cell count abnormal ": 3.17015856026532, "White blood cell count decreased ": 6.617793594097158, "Wound dehiscence ": 35.20135165165497, "Wound infection ": 4.881148648130219}
\ No newline at end of file
+{"Completed suicide": 69.70506869533357}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/167.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/167.json
index d8df6cbc4cb..9cbf8275525 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/167.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/167.json
@@ -1 +1 @@
-{"Bronchitis ": 14.135005294474642, "Chronic obstructive pulmonary disease ": 34.20696330066647, "Dyspnoea ": 3.972088226332475, "Intentional product misuse ": 14.79702221649479, "Pneumonia ": 3.3505466030642728, "Product dose omission issue ": 5.51857019316779}
\ No newline at end of file
+{"Intentional overdose": 80.7833639710511, "Suicide attempt": 78.03396815773459, "Tachycardia": 18.145696087714114}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/168.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/168.json
index 28ab7b71676..0082c06c08f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/168.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/168.json
@@ -1 +1 @@
-{"Angioedema ": 2.6539705283655963, "Body temperature increased ": 2.7076601556616646, "Cellulitis ": 3.856011339805866, "Cold sweat ": 3.460811840194528, "Crying ": 20.44550760353357, "Cyanosis ": 12.376612908596352, "Decreased appetite ": 2.777760909669821, "Eczema ": 2.410617965282814, "Erythema ": 2.397858542507614, "Eye movement disorder ": 10.199011013669768, "Febrile convulsion ": 69.78941375597832, "Gait inability ": 2.21949700602106, "Guillain-Barre syndrome ": 3.5498812893631344, "Haematochezia ": 4.255025238763068, "Hyperpyrexia ": 6.059754661276945, "Hyporesponsive to stimuli ": 61.32549657098565, "Hypothermia ": 13.4248188900688, "Hypotonia ": 11.735787655751778, "Hypotonic-hyporesponsive episode ": 80.07405606071534, "Immunisation reaction ": 3.763094068200025, "Infantile vomiting ": 297.95322778250386, "Injection site mass ": 7.726266586601151, "Irritability ": 10.749402520194906, "Irritability postvaccinal ": 18.888237832198858, "Kawasaki's disease ": 93.7734614942848, "Lethargy ": 4.853299975916843, "Loss of consciousness ": 3.202554283668737, "Meningitis ": 12.117142794974749, "Meningococcal bacteraemia ": 447.5382783503141, "Pallor ": 14.245331492820604, "Paralysis ": 3.590123010712093, "Petechiae ": 4.397909738079209, "Posture abnormal ": 23.76643216495098, "Product administered to patient of inappropriate age ": 14.268787928159856, "Pyrexia ": 3.79542759923243, "Rash ": 2.2926588611246133, "Rash macular ": 3.6023462519664937, "Rash morbilliform ": 4.909259802355567, "Respiratory arrest ": 2.569335674791817, "Restlessness ": 2.401166784073336, "Seizure ": 3.867691781636057, "Somnolence ": 2.163550754731656, "Syncope ": 3.7714220368277056, "Tearfulness ": 12.311305309757472, "Unresponsive to stimuli ": 9.055974891140345, "Urticaria ": 2.8493186136188005, "Vaccination site erythema ": 3.959442749890447, "Vaccination site induration ": 12.242806762004076, "Vaccination site mass ": 19.94983584023073, "Vaccination site oedema ": 7.991036305563466, "Vaccination site reaction ": 2.962587909400165, "Vaccination site swelling ": 2.979605448560456, "Vomiting ": 2.693540825851686}
\ No newline at end of file
+{"Abortion spontaneous": 2.312950445121351, "Abscess": 10.47828900988403, "Adverse event": 2.0845571676533283, "Alanine aminotransferase increased": 4.315551531010428, "Application site erythema": 5.274827850391704, "Aspartate aminotransferase increased": 4.192710698141751, "Ataxia": 3.682963182425097, "Autoimmune hepatitis": 11.16210432686378, "Autoimmune thyroiditis": 6.594795665515045, "Breast cancer": 2.9509869245289586, "Cardiomyopathy": 4.149613964252412, "Cellulitis": 4.31690922074272, "Depressed mood": 2.510332754822995, "Depression": 3.182238101549189, "Device operational issue": 29.42985552102633, "Dilated cardiomyopathy": 6.03127253524514, "Drug delivery system malfunction": 9.141797321708395, "Erysipelas": 5.753397019313024, "Expanded disability status scale score increased": 263.1656190182535, "Gait disturbance": 3.1364576886390454, "Gait inability": 2.088595588605608, "Gamma-glutamyltransferase increased": 8.029269148548016, "Hemiparesis": 3.033009720895796, "Hemiplegia": 2.756704943379932, "Hepatic enzyme increased": 2.4083389078484605, "Hepatic steatosis": 3.333658828091606, "Hepatitis": 3.45065821253789, "Hyperthyroidism": 2.673408447388397, "Incorrect dose administered by device": 15.98675005858739, "Influenza like illness": 5.200479261848722, "Injection site abscess": 192.44242192436116, "Injection site atrophy": 94.60407854944586, "Injection site bruising": 8.995978415991233, "Injection site cellulitis": 88.50121750688037, "Injection site discolouration": 49.09361632465938, "Injection site erythema": 6.455033157458272, "Injection site haematoma": 3.429145212862429, "Injection site haemorrhage": 7.617306709067428, "Injection site induration": 19.87274297123187, "Injection site infection": 69.9395905386055, "Injection site inflammation": 3.108856076207028, "Injection site mass": 14.03604619650286, "Injection site necrosis": 242.46496516396616, "Injection site nodule": 16.28219088088887, "Injection site oedema": 5.977001823109292, "Injection site pain": 3.424876176844528, "Injection site rash": 8.279254956593867, "Injection site reaction": 11.620657051754536, "Injection site ulcer": 150.39654939070428, "Jaundice": 2.5575392497411418, "Leukopenia": 2.845303757291461, "Liver function test increased": 10.74301469681734, "Lymphocyte count decreased": 6.762588910126118, "Lymphopenia": 3.0272881448863496, "Mobility decreased": 2.501567399333673, "Multiple sclerosis": 69.19632833547284, "Multiple sclerosis relapse": 83.12951191182691, "Muscle rigidity": 2.472485330421788, "Muscle spasticity": 12.427193403691309, "Muscular weakness": 3.045618896583388, "Nephrotic syndrome": 4.276446191708813, "Neuromyelitis optica spectrum disorder": 36.07455045600889, "No adverse event": 2.098320871672575, "Optic neuritis": 15.885276611415652, "Panniculitis": 13.03687385137447, "Paralysis": 2.8328005403394143, "Paraparesis": 13.538559077179602, "Product dose omission issue": 3.6202939883059706, "Rash macular": 2.0246893428786588, "Raynaud's phenomenon": 6.364718809565585, "Secondary progressive multiple sclerosis": 75.64917814063908, "Sensory disturbance": 2.8814928679209904, "Skin necrosis": 29.481193262851587, "Skin reaction": 5.756386793338486, "Skin ulcer": 2.697398202199367, "Thrombotic microangiopathy": 10.124776492912403, "Transaminases increased": 3.9775351010221183, "Urinary incontinence": 2.035830871649755}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/169.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/169.json
index 2a21a31a377..5655240c639 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/169.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/169.json
@@ -1 +1 @@
-{"Blood cholesterol increased ": 6.180819101429842, "Blood creatinine decreased ": 159.54988924297095, "Blood creatinine increased ": 2.8211783586784347, "Bradycardia ": 3.4062872234417187, "Cardiac disorder ": 4.409715635119716, "Drug interaction ": 2.094528464281381, "Emotional disorder ": 17.042091928144742, "Feeling abnormal ": 4.6862804188714735, "Flushing ": 4.442430610325446, "Gait disturbance ": 3.784012884400332, "Hallucination ": 2.919419191066829, "Hip fracture ": 20.60198940620528, "Hyperaemia ": 51.88735480816836, "Hyperkalaemia ": 3.559725561765743, "Hyponatraemia ": 4.863811378765752, "Joint effusion ": 30.172665544142905, "Muscle twitching ": 10.747460803875107, "Muscular weakness ": 3.302635869460995, "Oral candidiasis ": 12.170827291552945, "Post procedural infection ": 129.32191508716056}
\ No newline at end of file
+{"Arrhythmia": 4.803171294325519, "Atrial fibrillation": 8.629216865526962, "Bladder pain": 40.77052339943651, "Blood pressure increased": 13.212569521215077, "Blood pressure systolic increased": 7.600927591689569, "Blood urine present": 6.610177408113944, "Constipation": 7.540772653140951, "Cystitis": 9.102223441629466, "Dizziness": 2.0706296793608265, "Drug ineffective for unapproved indication": 4.61108210231941, "Drug interaction": 4.181480808333663, "Dry eye": 6.721857575798488, "Dry mouth": 11.685931224457336, "Dry throat": 5.28052200494966, "Dyspepsia": 2.592440165742671, "Dysuria": 14.081119804603617, "Erectile dysfunction": 3.740623297324343, "Eye swelling": 3.440645511527012, "Eyelid oedema": 7.685191081438687, "Flatulence": 2.2741210454741028, "Gastritis": 2.879069385533123, "Glaucoma": 3.0240552842945814, "Heart rate increased": 2.699753889760992, "Heart rate irregular": 3.0533519580028323, "Hypertension": 6.695380004484429, "Hypertensive crisis": 14.94899623366564, "Hypertonic bladder": 25.58645950238521, "Inappropriate schedule of product administration": 2.651116169060718, "Incontinence": 4.789270373588477, "Intentional product misuse": 2.4986282477666037, "Joint swelling": 2.239649734535078, "Micturition urgency": 16.102872177207068, "Mouth swelling": 3.7193403503664033, "Nightmare": 2.382205075119483, "Nocturia": 28.62102145270435, "Oedema peripheral": 2.1304251452758947, "Palpitations": 5.7441885439448175, "Petechiae": 2.477451035451456, "Pollakiuria": 14.005895435295397, "Product availability issue": 7.985409058127021, "Product use in unapproved indication": 3.3019900668903177, "Purpura": 2.520140639626995, "Swelling of eyelid": 7.483972351985338, "Swollen tongue": 2.2244958654832154, "Tachycardia": 4.853257752633187, "Therapeutic product effect incomplete": 2.971112277528776, "Urinary hesitation": 17.972295595713625, "Urinary incontinence": 13.598836000635425, "Urinary retention": 43.47283709846098, "Urinary tract infection": 6.375076444038133, "Urine flow decreased": 24.517146887549977, "Urine odour abnormal": 12.27151118323859, "Vulvovaginal pruritus": 22.8773739055385, "Wrong technique in product usage process": 5.946208146776063}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/17.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/17.json
index 562ef46bc86..a488d6589e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/17.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/17.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 11.778627414771696, "Abdominal pain upper ": 8.813337145569657, "Abnormal loss of weight ": 176.27066865559016, "Adverse reaction ": 57.00408155795449, "Arthropathy ": 16.52024151786227, "Deafness ": 38.75254920919572, "Deafness transitory ": 1249.3627683550633, "Decreased appetite ": 7.199476609854669, "Dizziness ": 2.223114597294125, "Drug hypersensitivity ": 12.516584371520928, "Ear infection ": 109.60648405525048, "Eating disorder ": 72.70826667000149, "Feeding disorder ": 81.33244164644749, "Foot operation ": 349.00448361854524, "Functional gastrointestinal disorder ": 328.6286408623495, "Gastrointestinal disorder ": 13.93005290067236, "Gastrointestinal pain ": 50.74511261053413, "Hypophagia ": 59.72216539564591, "Musculoskeletal disorder ": 92.05833702424012, "Pharyngitis ": 102.16034905003669, "Shoulder arthroplasty ": 383.6489020464991, "Weight decreased ": 4.792868753691911}
\ No newline at end of file
+{"Drug ineffective": 23.070269364319884, "Macular degeneration": 2094.342912544314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/170.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/170.json
index 59a82aa841e..0d6c802d4f8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/170.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/170.json
@@ -1 +1 @@
-{"Abnormal dreams ": 16.211473568022807, "Abnormal weight gain ": 13.905583323339515, "Abortion induced ": 4.250644590181727, "Accident at work ": 60.87521138170389, "Acquired immunodeficiency syndrome ": 23.28897853761737, "Adverse event ": 2.7364351129835174, "Affective disorder ": 8.379935378050146, "Anxiety disorder ": 3.982353311394032, "Benign prostatic hyperplasia ": 15.761002625669224, "Bipolar disorder ": 5.280026385650897, "Blood HIV RNA ": 128.9348046977465, "Blood HIV RNA increased ": 172.74621696273675, "Blood blister ": 8.257055944504613, "Blood creatinine increased ": 2.550198041659546, "Blood lactic acid increased ": 2.7151965260776745, "Blood triglycerides increased ": 6.129767437266305, "Bronchitis ": 2.0710222520168773, "CD4 lymphocytes decreased ": 124.22977397105107, "Carotid arteriosclerosis ": 30.269188311999528, "Cerebral toxoplasmosis ": 30.995252689560772, "Circumstance or information capable of leading to medication error ": 12.11422014400143, "Creatinine renal clearance decreased ": 3.012603968842698, "Cyst ": 4.530478312022907, "Dental caries ": 2.6212489157039336, "Depressed mood ": 2.037233620709862, "Depression ": 3.8598489202733943, "Dermatitis ": 7.073607594804571, "Diabetes mellitus ": 3.305771177309938, "Diffuse alopecia ": 14.41012687130484, "Drug ineffective ": 2.3654329302696686, "Drug resistance ": 13.496253773232944, "Drug resistance mutation ": 183.54765795258527, "Dupuytren's contracture ": 35.86342570000992, "Dyslipidaemia ": 4.884081244106118, "Dyspepsia ": 2.306119251792408, "Dysphagia ": 4.029437877438168, "Emotional disorder ": 2.010543519809912, "Endotracheal intubation ": 16.436345289081938, "Erectile dysfunction ": 4.050412169837435, "Face injury ": 7.775094238083694, "Family stress ": 326.2548304959832, "Fat tissue increased ": 18.385815114805084, "Gastrointestinal disorder ": 3.0949681250574987, "Gastrointestinal tube insertion ": 83.8861499345394, "Gastrostomy ": 39.71666788395807, "Genotype drug resistance test positive ": 115.6037006985006, "Gestational diabetes ": 5.749868437892848, "Glaucoma ": 2.201854598827318, "Glomerular filtration rate decreased ": 10.884422190208015, "Glycosylated haemoglobin increased ": 4.106038528650144, "Gonorrhoea ": 111.74457758253568, "Gynaecomastia ": 4.400034294832929, "HIV infection ": 30.24915229169567, "HIV test positive ": 41.80907631172655, "HIV viraemia ": 118.78717738244588, "HIV-associated neurocognitive disorder ": 33.207019396040145, "Haemodialysis ": 10.926470096349258, "Helicobacter infection ": 2.1989374407539364, "Hepatic cirrhosis ": 3.250563380271834, "Hepatic cytolysis ": 2.354104322739183, "Hepatic steatosis ": 4.072503965535388, "Hepatitis B ": 5.74237078064502, "Hepatitis B DNA increased ": 11.023349431784432, "Hepatitis B reactivation ": 3.928729798195381, "Hypercalcaemia ": 7.541415654461298, "Hypercholesterolaemia ": 2.1680425463694517, "Hyperemesis gravidarum ": 47.90612869601023, "Hyperlipidaemia ": 4.419280726988122, "Hyperphagia ": 9.106304444674963, "Hypersomnia ": 2.0124037593218724, "Hypertriglyceridaemia ": 2.345542398288093, "Immune reconstitution inflammatory syndrome ": 62.17207505972675, "Increased appetite ": 4.289390165041169, "Ingrown hair ": 73.6878714520271, "Initial insomnia ": 6.7353978046103, "Insomnia ": 2.9426045212257823, "Intentional dose omission ": 6.3712044032950805, "Intertrigo ": 195.03934183053948, "Intervertebral disc degeneration ": 2.508563819178304, "Joint noise ": 9.535371885678456, "Kaposi's sarcoma ": 30.559655366828103, "Lactic acidosis ": 2.818647919224698, "Libido decreased ": 3.1649080604128565, "Ligament sprain ": 19.833474889458245, "Lipids abnormal ": 57.20426184527183, "Lipodystrophy acquired ": 9.772942216336924, "Live birth ": 6.978214306370388, "Liver function test increased ": 3.3178096774942105, "Loss of libido ": 6.791091788636486, "Low density lipoprotein increased ": 6.782848910948265, "Lumbar spinal stenosis ": 48.03791963540094, "Lung consolidation ": 20.874198792914715, "Lymphoma ": 3.6713867640859537, "Major depression ": 3.869531464238956, "Maternal exposure during pregnancy ": 3.3975395285741725, "Mechanical ventilation ": 5.804577235091415, "Meningitis cryptococcal ": 22.12526967402916, "Menopausal symptoms ": 30.25483376445725, "Mental disorder ": 4.062789468605201, "Mental status changes ": 4.74743931081544, "Metabolic disorder ": 24.792700553421984, "Middle insomnia ": 2.039092749231868, "Miosis ": 2.1669781331918214, "Mitochondrial DNA mutation ": 106.42441620614947, "Monkeypox ": 572.2812317977036, "Muscle atrophy ": 3.983226531210247, "Mycobacterium avium complex infection ": 15.940841457075749, "Mycoplasma genitalium infection ": 1155.9796967217178, "Myositis ": 3.2123078701029257, "Nervous system disorder ": 7.323679230407762, "Neuropathy peripheral ": 2.100732525336884, "Neuropsychiatric syndrome ": 118.46683606821615, "Nightmare ": 8.013305430925737, "Obesity ": 3.6439446922268695, "Opportunistic infection ": 19.559388367292687, "Paranoia ": 2.364334584402473, "Pathogen resistance ": 2.5144235375035864, "Persecutory delusion ": 6.87463343559486, "Pigmentation disorder ": 14.009123986857192, "Pneumocystis jirovecii pneumonia ": 6.084671348336378, "Pneumomediastinum ": 19.300673001841798, "Pneumonia streptococcal ": 45.13149165628347, "Pneumothorax ": 2.04675400184223, "Poisoning deliberate ": 3.7420826116033674, "Premature delivery ": 3.368697788612041, "Product blister packaging issue ": 29.42146536340325, "Product package associated injury ": 21.230167513596108, "Product packaging difficult to open ": 40.79061362810873, "Product use complaint ": 5.0528863367305, "Progressive multifocal leukoencephalopathy ": 4.782743068794248, "Psychiatric symptom ": 2.997034679642722, "Rales ": 6.495677077113978, "Renal colic ": 8.771942670261758, "Renal impairment ": 2.327615898201357, "Rhonchi ": 21.339886093385932, "Scoliosis ": 3.682927665137964, "Skin lesion ": 2.11391998122753, "Sleep 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4.014739647276096}
\ No newline at end of file
+{"Abdominal abscess": 6.02159727780756, "Abscess": 2.240269615809685, "Acquired gene mutation": 12.306730400452308, "Acute abdomen": 9.430101519110217, "Acute myeloid leukaemia": 3.294756157381137, "Adenocarcinoma": 9.852134001960035, "Adenocarcinoma of colon": 30.152565133733404, "Anaemia": 2.5410024086443577, "Anastomotic leak": 79.36471230496774, "Ascites": 4.262528384897177, "Astrocytoma, low grade": 80.95628758729818, "Autoimmune haemolytic anaemia": 2.579597251181986, "Bacteraemia": 5.798327559536754, "Blindness": 2.895462535170649, "Blood albumin decreased": 4.083002261962488, "Blood pressure diastolic increased": 19.37512379610329, "Body temperature decreased": 7.169260074156138, "Bone marrow disorder": 25.064373326181546, "Bone marrow failure": 3.1493130140358145, "Breast cancer metastatic": 2.270013559700933, "Candida infection": 4.3158449067761815, "Carcinoembryonic antigen increased": 20.610920677614256, "Cardiotoxicity": 4.402084406818741, "Colitis ischaemic": 2.1493355524969098, "Colon cancer": 3.239982327854637, "Colon cancer metastatic": 49.09505698256709, "Colorectal cancer metastatic": 122.2064742113318, "Coma scale abnormal": 9.994774013281198, "Deep vein thrombosis": 2.5383186231088914, "Dehydration": 2.1135281926663585, "Dermatitis acneiform": 7.303255949384154, "Diarrhoea": 2.9592268832150186, "Disease progression": 17.281112030223383, "Disease recurrence": 2.994150114643769, "Drug resistance": 4.202504207876552, "Eastern Cooperative Oncology Group performance status worsened": 32.276525683333055, "Ejection fraction decreased": 2.3406295322678123, "Embolism": 5.380435493848728, "Embolism venous": 7.702461443491805, "Enteritis": 4.476629499169423, "Enterocolitis": 2.4429046799593, "Epistaxis": 5.929418028509372, "Febrile neutropenia": 7.7676878240503, "Fistula": 4.161364474694855, "Fournier's gangrene": 5.995825775030709, "Gastrointestinal disorder": 2.664944737595333, "Gastrointestinal haemorrhage": 2.0859819618239595, "Gastrointestinal motility disorder": 3.7108926359442544, "Gastrointestinal necrosis": 8.293772423064224, "Gastrointestinal perforation": 21.121010421757383, "Gastrointestinal toxicity": 20.4935059291466, "Gene mutation": 13.106333568065692, "Glioblastoma": 12.375672133402112, "Granulocyte count decreased": 7.378486904499383, "Haematocrit decreased": 2.7685056792677663, "Haematotoxicity": 25.02103812619014, "Haemoglobin abnormal": 3.67771627201035, "Haemoglobin decreased": 2.434953758369394, "Haemoptysis": 2.453586118885069, "Hemiparesis": 3.5812492659425463, "Hepatic failure": 2.0119081364082563, "Hepatic steatosis": 2.272649865702409, "Hepatitis B reactivation": 12.334511336931543, "Hiccups": 7.78733258193343, "Hydronephrosis": 2.404461363534158, "Hyperammonaemia": 2.0898157263847645, "Hyperammonaemic encephalopathy": 7.957426675733114, "Hyperbilirubinaemia": 3.191516553236521, "Hypertension": 4.428528637107231, "Hypoalbuminaemia": 3.72984040964318, "Hypomagnesaemia": 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"Mental status changes": 3.031309131044261, "Metastases to bone": 7.592950924618542, "Metastases to bone marrow": 31.496876905278054, "Metastases to central nervous system": 8.101445073977075, "Metastases to liver": 21.029893162562253, "Metastases to lung": 17.92804658710671, "Metastases to lymph nodes": 11.968733044344486, "Metastases to ovary": 56.616936146391545, "Metastases to peritoneum": 19.614781649694724, "Metastases to pleura": 20.31589952636521, "Metastases to spine": 7.483743528326173, "Metastasis": 2.6264737549312365, "Metastatic neoplasm": 9.871907193808552, "Mouth ulceration": 2.3388730944142164, "Mucosal inflammation": 9.182907809795529, "Multiple-drug resistance": 2.8189290424931954, "Myelodysplastic syndrome": 2.635720620967005, "Myelosuppression": 18.716541768337738, "Neoplasm": 2.3676680354595434, "Neoplasm progression": 13.495650407854704, "Nephrotic syndrome": 6.040599789249148, "Nerve injury": 5.363456950588303, "Nervous system disorder": 3.1138047651033456, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/171.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/171.json
index b3b0de4fd17..5c62956bcf7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/171.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/171.json
@@ -1 +1 @@
-{"Corneal oedema ": 572.2240041111621, "Intraocular pressure increased ": 333.7598422419329}
\ No newline at end of file
+{"Bronchitis": 14.134157878480185, "Chronic obstructive pulmonary disease": 34.20696330066647, "Dyspnoea": 3.972029214668367, "Intentional product misuse": 14.79702221649479, "Pneumonia": 3.3505466030642728, "Product dose omission issue": 5.51857019316779}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/172.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/172.json
index b3c04094149..7aed68c256a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/172.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/172.json
@@ -1 +1 @@
-{"Acute kidney injury ": 3.0490634849604894, "Colitis ": 15.530351206102909, "Disease progression ": 3.22284175241883, "Liver disorder ": 8.394019310031123, "Malignant melanoma ": 46.72571709494515, "Malignant neoplasm progression ": 9.035119602991468, "Neoplasm progression ": 8.657878374988124, "Off label use ": 3.258467250835774, "Product use in unapproved indication ": 5.935070801449918, "Serous retinal detachment ": 313.3136554751918, "Uveitis ": 25.963781361970856, "Vision blurred ": 2.65054032262972}
\ No newline at end of file
+{"Angioedema": 2.642333193522215, "Body temperature increased": 2.695787207973562, "Cellulitis": 3.8391068811057782, "Cold sweat": 3.4456408822460363, "Crying": 20.351109644170656, "Cyanosis": 12.320032584541512, "Decreased appetite": 2.765546853874564, "Eczema": 2.4000514267783606, "Erythema": 2.387315887046688, "Eye movement disorder": 10.154305405513805, "Febrile convulsion": 69.45858474914962, "Gait inability": 2.209768213881706, "Guillain-Barre syndrome": 3.534322219722199, "Haematochezia": 4.235949557450641, "Hyperpyrexia": 6.033188628178409, "Hyporesponsive to stimuli": 61.05668844628617, "Hypothermia": 13.365963223585394, "Hypotonia": 11.683067915618995, "Hypotonic-hyporesponsive episode": 79.72292340643273, "Immunisation reaction": 3.746596616094324, "Infantile vomiting": 296.64694850554986, "Injection site mass": 7.692400676067793, "Irritability": 10.701735980202338, "Irritability postvaccinal": 18.805435131999744, "Kawasaki's disease": 93.15436537267972, "Lethargy": 4.8320162609010895, "Loss of consciousness": 3.1883506606772016, "Meningitis": 12.064029398691202, "Meningococcal bacteraemia": 445.5767647044845, "Pallor": 14.181942130033738, "Paralysis": 3.57438712723642, "Petechiae": 4.378631320491999, "Posture abnormal": 23.66226453249875, "Product administered to patient of inappropriate age": 14.206238764152433, "Pyrexia": 3.793305405671294, "Rash": 2.282563936741774, "Rash macular": 3.586554509407911, "Rash morbilliform": 4.887741439454701, "Respiratory arrest": 2.558074007313248, "Restlessness": 2.3905148195120827, "Seizure": 3.85029286621796, "Somnolence": 2.1540369284982006, "Syncope": 3.7548240171821994, "Tearfulness": 12.257345120312715, "Unresponsive to stimuli": 9.01527595938641, "Urticaria": 2.8367886251650143, "Vaccination site erythema": 3.942080530266587, "Vaccination site induration": 12.189139968881756, "Vaccination site mass": 19.86238508523226, "Vaccination site oedema": 7.956006488224018, "Vaccination site reaction": 2.949434499431613, "Vaccination site swelling": 2.96654134738215, "Vomiting": 2.6816792806392376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/173.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/173.json
index b1314758fff..356480200d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/173.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/173.json
@@ -1 +1 @@
-{"Anaemia ": 6.236287167680149, "Aplasia pure red cell ": 172.36431590406747, "Disease progression ": 2.6595364504418875, "Drug ineffective ": 2.4356686940264782, "Dyspnoea exertional ": 5.943574659825215, "Dysuria ": 6.802686601984546, "Ejection fraction decreased ": 14.655123957676537, "Eosinophilia ": 8.870304500094988, "Face oedema ": 8.155972602707898, "Febrile bone marrow aplasia ": 95.85085367940256, "Generalised oedema ": 20.58629853871493, "Haemoglobin decreased ": 17.484827947962575, "Hyperkalaemia ": 4.1854908015195935, "Pruritus ": 3.5176137602039232, "Pulmonary embolism ": 2.3926110737733217, "Rash maculo-papular ": 6.885778303271618, "Therapy non-responder ": 29.646928610442718}
\ No newline at end of file
+{"Blood cholesterol increased": 6.180819101429842, "Blood creatinine decreased": 159.54988924297095, "Blood creatinine increased": 2.8211783586784347, "Bradycardia": 3.406180478568081, "Cardiac disorder": 4.409715635119716, "Drug interaction": 2.094528464281381, "Emotional disorder": 17.042091928144742, "Feeling abnormal": 4.686190206032684, "Flushing": 4.442430610325446, "Gait disturbance": 3.783944280777854, "Hallucination": 2.919419191066829, "Hip fracture": 20.60198940620528, "Hyperaemia": 51.85667503452572, "Hyperkalaemia": 3.5592348383079604, "Hyponatraemia": 4.863811378765752, "Joint effusion": 30.172665544142905, "Muscle twitching": 10.747460803875107, "Muscular weakness": 3.302635869460995, "Oral candidiasis": 12.170827291552945, "Post procedural infection": 129.32191508716056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/174.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/174.json
index 56544ba5682..28c7041859c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/174.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/174.json
@@ -1 +1 @@
-{"Drug dose omission by device ": 1047.2784940604204, "Drug ineffective ": 3.7086581161675607, "Dyspnoea ": 7.955694403386494}
\ No newline at end of file
+{"Abnormal dreams": 16.211473568022807, "Abnormal weight gain": 13.905583323339515, "Abortion induced": 4.250644590181727, "Accident at work": 60.87521138170389, "Acquired immunodeficiency syndrome": 23.28897853761737, "Adverse event": 2.7364351129835174, "Affective disorder": 8.379935378050146, "Anxiety disorder": 3.982353311394032, "Benign prostatic hyperplasia": 15.761002625669224, "Bipolar disorder": 5.280026385650897, "Blood HIV RNA": 128.9348046977465, "Blood HIV RNA increased": 172.74621696273675, "Blood blister": 8.257055944504613, "Blood creatinine increased": 2.550198041659546, "Blood lactic acid increased": 2.7151965260776745, "Blood triglycerides increased": 6.129767437266305, "Bronchitis": 2.0708979039521043, "CD4 lymphocytes decreased": 124.22977397105107, "Carotid arteriosclerosis": 30.269188311999528, "Cerebral toxoplasmosis": 30.995252689560772, "Circumstance or information capable of leading to medication error": 12.11422014400143, "Creatinine renal clearance decreased": 3.012603968842698, "Cyst": 4.530478312022907, "Dental caries": 2.6212489157039336, "Depressed mood": 2.037233620709862, "Depression": 3.8598489202733943, "Dermatitis": 7.072677019060918, "Diabetes mellitus": 3.305771177309938, "Diffuse alopecia": 14.41012687130484, "Drug ineffective": 2.365415411750074, "Drug resistance": 13.496253773232944, "Drug resistance mutation": 183.54765795258527, "Dupuytren's contracture": 35.86342570000992, "Dyslipidaemia": 4.884081244106118, "Dyspepsia": 2.306119251792408, "Dysphagia": 4.029437877438168, "Emotional disorder": 2.010543519809912, "Endotracheal intubation": 16.436345289081938, "Erectile dysfunction": 4.050412169837435, "Face injury": 7.775094238083694, "Family stress": 326.2548304959832, "Fat tissue increased": 18.385815114805084, "Gastrointestinal disorder": 3.094870441497407, "Gastrointestinal tube insertion": 83.8861499345394, "Gastrostomy": 39.71666788395807, "Genotype drug resistance test positive": 115.6037006985006, "Gestational diabetes": 5.749868437892848, "Glaucoma": 2.201854598827318, "Glomerular filtration rate decreased": 10.884422190208015, "Glycosylated haemoglobin increased": 4.106038528650144, "Gonorrhoea": 111.74457758253568, "Gynaecomastia": 4.400034294832929, "HIV infection": 30.24915229169567, "HIV test positive": 41.80907631172655, "HIV viraemia": 118.78717738244588, "HIV-associated neurocognitive disorder": 33.207019396040145, "Haemodialysis": 10.926470096349258, "Helicobacter infection": 2.1989374407539364, "Hepatic cirrhosis": 3.250563380271834, "Hepatic cytolysis": 2.354104322739183, "Hepatic steatosis": 4.072503965535388, "Hepatitis B": 5.74237078064502, "Hepatitis B DNA increased": 11.023349431784432, "Hepatitis B reactivation": 3.928729798195381, "Hypercalcaemia": 7.541415654461298, "Hypercholesterolaemia": 2.1680425463694517, "Hyperemesis gravidarum": 47.90612869601023, "Hyperlipidaemia": 4.419280726988122, "Hyperphagia": 9.106304444674963, "Hypersomnia": 2.0124037593218724, 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3.869531464238956, "Maternal exposure during pregnancy": 3.3975395285741725, "Mechanical ventilation": 5.804577235091415, "Meningitis cryptococcal": 22.12526967402916, "Menopausal symptoms": 30.25483376445725, "Mental disorder": 4.062789468605201, "Mental status changes": 4.74743931081544, "Metabolic disorder": 24.792700553421984, "Middle insomnia": 2.039092749231868, "Miosis": 2.1669781331918214, "Mitochondrial DNA mutation": 106.42441620614947, "Monkeypox": 572.2812317977036, "Muscle atrophy": 3.983226531210247, "Mycobacterium avium complex infection": 15.940841457075749, "Mycoplasma genitalium infection": 1155.9796967217178, "Myositis": 3.2123078701029257, "Nervous system disorder": 7.323679230407762, "Neuropathy peripheral": 2.100668652330113, "Neuropsychiatric syndrome": 118.46683606821615, "Nightmare": 8.013305430925737, "Obesity": 3.6439446922268695, "Opportunistic infection": 19.559388367292687, "Paranoia": 2.364334584402473, "Pathogen resistance": 2.5144235375035864, 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carcinoma": 3.2673801541628475, "Suicidal ideation": 2.8649128766169167, "Suspected counterfeit product": 5.342464289449949, "Syphilis": 36.58830183238787, "Tinea pedis": 56.24260744027168, "Toxic skin eruption": 2.094274620573904, "Treatment failure": 2.8643513062480093, "Treatment noncompliance": 15.8617401354794, "Trigeminal nerve disorder": 25.901010519695184, "Tuberculosis": 6.468261637296992, "Unevaluable event": 3.511134094175433, "Viraemia": 222.2101632400498, "Viral load": 170.87287612535974, "Viral load abnormal": 663.6979522012074, "Viral load decreased": 137.51745744674574, "Viral load increased": 128.68420443678886, "Viral mutation identified": 17.591802484957203, "Virologic failure": 29.66360819641498, "Weight increased": 24.17852742027715, "Weight loss poor": 14.856736575321465, "Wrong technique in product usage process": 4.014739647276096}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/175.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/175.json
index b1570f43617..e14fdb7924b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/175.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/175.json
@@ -1 +1 @@
-{"Abdominal distension ": 855.8100398003756}
\ No newline at end of file
+{"Corneal oedema": 572.2240041111621, "Intraocular pressure increased": 333.7598422419329}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/176.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/176.json
index f239221df5d..ef7727f869d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/176.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/176.json
@@ -1 +1 @@
-{"Anaemia ": 3.0723190181637587, "Death ": 2.9572882957974014, "Gastrointestinal haemorrhage ": 11.818976646273246, "Haemoglobin decreased ": 9.590683505364614, "Heparin-induced thrombocytopenia ": 175.5513554064213, "Hypotension ": 5.902491779083089, "Labelled drug-drug interaction medication error ": 34.98619302559191}
\ No newline at end of file
+{"Acute kidney injury": 3.0490634849604894, "Colitis": 15.530351206102909, "Disease progression": 3.22284175241883, "Liver disorder": 8.394019310031123, "Malignant melanoma": 46.72571709494515, "Malignant neoplasm progression": 9.035119602991468, "Neoplasm progression": 8.657878374988124, "Off label use": 3.258338900856551, "Product use in unapproved indication": 5.93488568748329, "Serous retinal detachment": 313.3136554751918, "Uveitis": 25.963781361970856, "Vision blurred": 2.65054032262972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/177.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/177.json
index 4fe26d19055..4306afe86db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/177.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/177.json
@@ -1 +1 @@
-{"Keratopathy ": 9172.99842238755, "Visual acuity reduced ": 316.1880632821686}
\ No newline at end of file
+{"Anaemia": 6.236287167680149, "Aplasia pure red cell": 172.36431590406747, "Disease progression": 2.6595364504418875, "Drug ineffective": 2.4356506875506394, "Dyspnoea exertional": 5.943574659825215, "Dysuria": 6.802686601984546, "Ejection fraction decreased": 14.655123957676537, "Eosinophilia": 8.870304500094988, "Face oedema": 8.155972602707898, "Febrile bone marrow aplasia": 95.85085367940256, "Generalised oedema": 20.58629853871493, "Haemoglobin decreased": 17.484827947962575, "Hyperkalaemia": 4.184913791176711, "Pruritus": 3.517571147023452, "Pulmonary embolism": 2.3926110737733217, "Rash maculo-papular": 6.885778303271618, "Therapy non-responder": 29.644334281742356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/178.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/178.json
index 6ef2552b304..ec568d59c5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/178.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/178.json
@@ -1 +1 @@
-{"Acute lymphocytic leukaemia ": 114.48249294546738, "Acute lymphocytic leukaemia recurrent ": 535.6643440204251, "Acute lymphocytic leukaemia refractory ": 834.8174089825604, "Alanine aminotransferase increased ": 2.857184249412659, "Anaemia ": 3.1432605657740136, "Aspergillus infection ": 42.72199471662792, "Bone marrow failure ": 27.93663564208738, "Clostridium difficile infection ": 11.4918429646483, "Coagulopathy ": 16.627766824131818, "Cytokine release syndrome ": 60.497231790518974, "Cytopenia ": 29.00294805645041, "Delirium ": 3.134748968349476, "Depressed level of consciousness ": 2.576851147746055, "Disease progression ": 7.475384834168018, "Drug ineffective for unapproved indication ": 8.556100378777122, "Embolism ": 18.088366983540254, "Febrile neutropenia ": 10.008951094035778, "Germ cell neoplasm ": 4947.162511445805, "Graft versus host disease ": 18.058109803042903, "Hepatotoxicity ": 7.607816770877876, "Hyperglycaemia ": 8.179014744524643, "Hyperphosphataemia ": 211.95152612027783, "Leukaemia recurrent ": 98.04356151587376, "Lung disorder ": 3.920680176271511, "Malignant neoplasm progression ": 3.878533800941676, "Metastases to bone marrow ": 317.92045073071745, "Neoplasm progression ": 3.416279302240109, "Neuropathy peripheral ": 2.9864335457249003, "Neurotoxicity ": 14.123888559518909, "Neutropenia ": 5.335643487125568, "Neutropenic sepsis ": 32.165819567441254, "Off label use ": 2.093882686445542, "Pancreatitis ": 3.1819150861582477, "Pancytopenia ": 6.2513125465939545, "Peripheral motor neuropathy ": 363.0720385040647, "Peripheral sensory neuropathy ": 33.80432070279049, "Renal impairment ": 2.636632530573024, "Second primary malignancy ": 16.436010274694794, "Therapy non-responder ": 5.974557480445643, "Thrombocytopenia ": 4.886012264838062, "Tracheitis ": 144.28751527791215, "Treatment failure ": 2.970588885580719, "Tubulointerstitial nephritis ": 8.279905589264084, "Unevaluable event ": 8.185316307199333, "Venoocclusive liver disease ": 33.65915950516605}
\ No newline at end of file
+{"Drug dose omission by device": 1047.2784940604204, "Drug ineffective": 3.7086307029420618, "Dyspnoea": 7.955576214560832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/179.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/179.json
index 01c42084e05..392c9fb920f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/179.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/179.json
@@ -1 +1 @@
-{"Acute lymphocytic leukaemia ": 93.27382365872154, "Acute lymphocytic leukaemia recurrent ": 595.8548514827819, "B precursor type acute leukaemia ": 776.1144927464509, "Bone marrow failure ": 20.26168879248283, "Central nervous system leukaemia ": 669.3600734530287, "Clostridium difficile colitis ": 24.28982063661031, "Constipation ": 2.07882795585028, "Cytokine release syndrome ": 70.70118927729445, "Cytomegalovirus infection ": 20.6074411769849, "Eating disorder ": 15.19177570764113, "Febrile neutropenia ": 10.8561907412344, "Gastrointestinal erosion ": 549.966731309946, "Gastrointestinal haemorrhage ": 2.7820656683259557, "Haematemesis ": 9.986197655076232, "Infection ": 3.0408832221837487, "Liver disorder ": 4.078308777820453, "Lymphocyte count decreased ": 48.75910590826577, "Melaena ": 9.931077907835238, "Mucormycosis ": 123.32032564269905, "Myelosuppression ": 4.683653799613817, "Neoplasm progression ": 5.854621454597867, "Neutrophil count decreased ": 9.51351592707919, "Pancytopenia ": 5.55301388025667, "Platelet count decreased ": 5.596612474194603, "Pleural effusion ": 4.258181333604145, "Pneumocystis jirovecii pneumonia ": 36.114422173161934, "Red blood cell count decreased ": 12.054738877525292, "Sepsis ": 9.684008856701356, "Staphylococcal infection ": 15.104143227457088, "Therapeutic product effect decreased ": 4.227545948602611, "Tumour lysis syndrome ": 42.451017519193314, "Visual impairment ": 2.485637782188793}
\ No newline at end of file
+{"Abdominal distension": 855.8100398003756}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/18.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/18.json
index 0c87ef90341..2930aed0303 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/18.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/18.json
@@ -1 +1 @@
-{"Coma ": 189.14256591198043, "Gastrooesophageal reflux disease ": 188.6548206410751, "Pneumonia aspiration ": 553.088874749223, "Somnolence ": 46.77244108890707}
\ No newline at end of file
+{"Abdominal discomfort": 11.778627414771696, "Abdominal pain upper": 8.813337145569657, "Abnormal loss of weight": 176.27066865559016, "Adverse reaction": 57.00408155795449, "Arthropathy": 16.52024151786227, "Deafness": 38.75254920919572, "Deafness transitory": 1249.3627683550633, "Decreased appetite": 7.199406773795759, "Dizziness": 2.223099164292213, "Drug hypersensitivity": 12.516584371520928, "Ear infection": 109.60648405525048, "Eating disorder": 72.70826667000149, "Feeding disorder": 81.33244164644749, "Foot operation": 349.00448361854524, "Functional gastrointestinal disorder": 328.6286408623495, "Gastrointestinal disorder": 13.929614256906678, "Gastrointestinal pain": 50.74511261053413, "Hypophagia": 59.72216539564591, "Musculoskeletal disorder": 92.03390998502832, "Pharyngitis": 102.13676139474896, "Shoulder arthroplasty": 383.6489020464991, "Weight decreased": 4.792868753691911}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/180.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/180.json
index 530de7e6c93..860bff9163f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/180.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/180.json
@@ -1 +1 @@
-{"Acute kidney injury ": 11.00017893332338, "Acute myocardial infarction ": 27.47800415566948, "Affective disorder ": 109.6591311425823, "Aggression ": 14.535234038188143, "Agitation ": 5.973381414487798, "Anaemia ": 6.289040513319541, "Atrial fibrillation ": 7.3001707767261905, "Atrial flutter ": 132.11433638144547, "Bradycardia ": 8.381657945700816, "Cardiac failure chronic ": 114.53269885402406, "Cardiac failure congestive ": 18.923635172649664, "Chronic obstructive pulmonary disease ": 10.863595264000493, "Gastrointestinal haemorrhage ": 7.374994973018202, "Hypotension ": 8.32530415512522, "Platelet count decreased ": 9.64128768973362, "Pneumonia ": 2.2590383605759903, "Syncope ": 3.374167327461674}
\ No newline at end of file
+{"Anaemia": 3.0723190181637587, "Death": 2.9572882957974014, "Gastrointestinal haemorrhage": 11.818976646273246, "Haemoglobin decreased": 9.590683505364614, "Heparin-induced thrombocytopenia": 175.5513554064213, "Hypotension": 5.902355330500766, "Labelled drug-drug interaction medication error": 34.98619302559191}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/181.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/181.json
index be15b1d1c89..0629acd4321 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/181.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/181.json
@@ -1 +1 @@
-{"Hepatitis A antibody positive ": 9765.233574728178, "Hepatitis C ": 86.9189159251557, "Suspected transmission of an infectious agent via product ": 2056.207203755685}
\ No newline at end of file
+{"Keratopathy": 9172.99842238755, "Visual acuity reduced": 316.1880632821686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/182.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/182.json
index 5feb7b4b5a9..ff81c781ed1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/182.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/182.json
@@ -1 +1 @@
-{"Adverse event ": 3.8930880723798102, "Aggression ": 2.9183720884033093, "Anaemia ": 27.212609499853823, "Ascites ": 9.402611649064644, "Depression ": 4.013447813294661, "Drug interaction ": 2.847572001412493, "Dysgeusia ": 6.934465018242256, "Haemoglobin decreased ": 3.3490557680806483, "Haemolytic anaemia ": 11.56926518439374, "Hepatic cirrhosis ": 7.646238729680586, "Hepatic encephalopathy ": 11.507872578266722, "Hepatic failure ": 5.513339956177235, "Hepatitis C ": 9.49460475171496, "Leukopenia ": 9.296073098498242, "Multiple organ dysfunction syndrome ": 3.90012924023044, "Neutropenia ": 10.433695598920425, "Oedema peripheral ": 2.395237920595602, "Pancytopenia ": 5.589816312299018, "Platelet count decreased ": 2.4932417112616867, "Red blood cell count decreased ": 4.92110523420947, "Sepsis ": 2.842931327301222, "Stomatitis ": 2.082148023449525, "Taste disorder ": 3.953089900554972, "Thrombocytopenia ": 5.258765823124525, "Urinary tract infection ": 2.0798926087033154, "Weight decreased ": 4.175382113698321, "White blood cell count decreased ": 2.1123775493664323}
\ No newline at end of file
+{"Acute lymphocytic leukaemia": 114.48249294546738, "Acute lymphocytic leukaemia recurrent": 535.6643440204251, "Acute lymphocytic leukaemia refractory": 834.8174089825604, "Alanine aminotransferase increased": 2.857184249412659, "Anaemia": 3.1432605657740136, "Aspergillus infection": 42.72199471662792, "Bone marrow failure": 27.93663564208738, "Clostridium difficile infection": 11.4918429646483, "Coagulopathy": 16.627766824131818, "Cytokine release syndrome": 60.497231790518974, "Cytopenia": 28.97982713359016, "Delirium": 3.134748968349476, "Depressed level of consciousness": 2.576851147746055, "Disease progression": 7.475384834168018, "Drug ineffective for unapproved indication": 8.556100378777122, "Embolism": 18.088366983540254, "Febrile neutropenia": 10.008951094035778, "Germ cell neoplasm": 4947.162511445805, "Graft versus host disease": 18.058109803042903, "Hepatotoxicity": 7.607816770877876, "Hyperglycaemia": 8.179014744524643, "Hyperphosphataemia": 211.95152612027783, "Leukaemia recurrent": 98.04356151587376, "Lung disorder": 3.920680176271511, "Malignant neoplasm progression": 3.878533800941676, "Metastases to bone marrow": 317.92045073071745, "Neoplasm progression": 3.416279302240109, "Neuropathy peripheral": 2.9863428799574843, "Neurotoxicity": 14.123888559518909, "Neutropenia": 5.335413957349636, "Neutropenic sepsis": 32.165819567441254, "Off label use": 2.093800206479514, "Pancreatitis": 3.1819150861582477, "Pancytopenia": 6.2513125465939545, "Peripheral motor neuropathy": 363.0720385040647, "Peripheral sensory neuropathy": 33.80432070279049, "Renal impairment": 2.636632530573024, "Second primary malignancy": 16.436010274694794, "Therapy non-responder": 5.974035475415775, "Thrombocytopenia": 4.885552478138239, "Tracheitis": 144.28751527791215, "Treatment failure": 2.970588885580719, "Tubulointerstitial nephritis": 8.279905589264084, "Unevaluable event": 8.185316307199333, "Venoocclusive liver disease": 33.65915950516605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/183.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/183.json
index e877f84e375..815500599f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/183.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/183.json
@@ -1 +1 @@
-{"Osteonecrosis of jaw ": 458.2330193518784}
\ No newline at end of file
+{"Acute lymphocytic leukaemia": 93.27382365872154, "Acute lymphocytic leukaemia recurrent": 595.8548514827819, "B precursor type acute leukaemia": 776.1144927464509, "Bone marrow failure": 20.26168879248283, "Central nervous system leukaemia": 669.3600734530287, "Clostridium difficile colitis": 24.28982063661031, "Constipation": 2.07882795585028, "Cytokine release syndrome": 70.70118927729445, "Cytomegalovirus infection": 20.6074411769849, "Eating disorder": 15.19177570764113, "Febrile neutropenia": 10.8561907412344, "Gastrointestinal erosion": 549.966731309946, "Gastrointestinal haemorrhage": 2.7820656683259557, "Haematemesis": 9.98531170035907, "Infection": 3.0408832221837487, "Liver disorder": 4.078308777820453, "Lymphocyte count decreased": 48.75910590826577, "Melaena": 9.929797071466137, "Mucormycosis": 123.32032564269905, "Myelosuppression": 4.683653799613817, "Neoplasm progression": 5.854621454597867, "Neutrophil count decreased": 9.51351592707919, "Pancytopenia": 5.55301388025667, "Platelet count decreased": 5.596612474194603, "Pleural effusion": 4.257789297340652, "Pneumocystis jirovecii pneumonia": 36.114422173161934, "Red blood cell count decreased": 12.054738877525292, "Sepsis": 9.684008856701356, "Staphylococcal infection": 15.104143227457088, "Therapeutic product effect decreased": 4.227545948602611, "Tumour lysis syndrome": 42.451017519193314, "Visual impairment": 2.485637782188793}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/184.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/184.json
index dadfb89866e..25b9cd4cbeb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/184.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/184.json
@@ -1 +1 @@
-{"Abdominal pain upper ": 2.576036982290252, "Acute phase reaction ": 1200.2870037727855, "Arthralgia ": 2.0490172957917334, "Atypical femur fracture ": 957.3265170684526, "Atypical fracture ": 1262.5054649581284, "Back pain ": 4.888974441123088, "Blood calcium increased ": 5.643798392857228, "Blood parathyroid hormone increased ": 18.091390498298043, "Bone disorder ": 4.904500151741326, "Bone pain ": 18.81208898325868, "Chest pain ": 2.377434051531969, "Compression fracture ": 22.27329326575435, "Dental caries ": 6.639198397293432, "Dyspepsia ": 2.550747412218436, "Ejection fraction decreased ": 6.229906672438436, "Exposed bone in jaw ": 165.77897804957803, "Extravasation ": 16.3326894785501, "Fall ": 2.630259655638741, "Femoral neck fracture ": 21.062285191614023, "Femur fracture ": 53.23844721348703, "Flatulence ": 2.4571567610133944, "Foot fracture ": 2.9904376969671675, "Fracture ": 6.166452749831576, "Gastric haemorrhage ": 4.123335901182265, "Gastric ulcer ": 2.826052122637696, "Gastritis ": 6.879406770703405, "Gingivitis ": 12.047995164160998, "Groin pain ": 5.077553307451468, "Hip fracture ": 4.057248599655636, "Hypercalcaemia ": 10.33021937226971, "Hypocalcaemia ": 9.375353809534593, "Impaired healing ": 3.9670913186831194, "Influenza like illness ": 3.49833481901078, "Infusion site extravasation ": 24.87970433586598, "Injection site extravasation ": 12.000684036178717, "Jaw disorder ": 25.82526582301634, "Loose tooth ": 27.42327193061157, "Low turnover osteopathy ": 901.5967187241832, "Lower limb fracture ": 3.8275476501795023, "Movement disorder ": 3.7582723028538094, "Musculoskeletal chest pain ": 3.539006726393864, "Musculoskeletal pain ": 4.984593009101706, "Musculoskeletal stiffness ": 2.4781772130800053, "Oesophageal ulcer ": 13.964751634701608, "Oesophagitis ": 20.14578747238701, "Osteitis ": 53.53767787315208, "Osteomyelitis ": 44.95133363244908, "Osteonecrosis ": 4.964407359658485, "Osteonecrosis of jaw ": 500.44137319738974, "Pain in jaw ": 12.582461971561989, "Pathological fracture ": 29.343236651921647, "Periodontitis ": 60.2509976744506, "Phlebitis ": 6.178977510161345, "Product administration error ": 4.101416489412935, "Rib fracture ": 3.260998281005002, "Spinal compression fracture ": 11.53334467187501, "Spinal fracture ": 5.619036141169437, "Spinal pain ": 5.677309521948742, "Stress fracture ": 74.54364290886284, "Tooth disorder ": 6.1082105189143565, "Tooth extraction ": 51.37317514056999, "Tooth fracture ": 6.912397091587622, "Toothache ": 6.53543194901932}
\ No newline at end of file
+{"Acute kidney injury": 11.00017893332338, "Acute myocardial infarction": 27.47800415566948, "Affective disorder": 109.6591311425823, "Aggression": 14.535234038188143, "Agitation": 5.973381414487798, "Anaemia": 6.289040513319541, "Atrial fibrillation": 7.299971513571996, "Atrial flutter": 132.11433638144547, "Bradycardia": 8.381395270500526, "Cardiac failure chronic": 114.53269885402406, "Cardiac failure congestive": 18.922203568784237, "Chronic obstructive pulmonary disease": 10.863595264000493, "Gastrointestinal haemorrhage": 7.374994973018202, "Hypotension": 8.325111662165197, "Platelet count decreased": 9.64128768973362, "Pneumonia": 2.2590383605759903, "Syncope": 3.3741208927076194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/185.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/185.json
index 7664719abaa..81316ea8143 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/185.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/185.json
@@ -1 +1 @@
-{"Abdominal abscess ": 39.64266638877553, "Abnormal behaviour ": 3.433742445346988, "Acute lymphocytic leukaemia ": 28.993445463826863, "Acute myeloid leukaemia ": 5.891836545351418, "Acute respiratory distress syndrome ": 3.196000370771182, "Amyloidosis ": 25.58679349938668, "Anaemia ": 2.41810699861508, "Ascites ": 3.767389091003765, "Aspergillus infection ": 6.431472475851303, "Atelectasis ": 13.363535612506402, "Bacteraemia ": 6.7030803846941245, "Bacterial sepsis ": 13.62871952846341, "Brain fog ": 3.80838561950461, "Brain oedema ": 5.656948749195101, "Bronchopulmonary aspergillosis ": 10.512663891943696, "Candida infection ": 10.194915393785427, "Cardiac failure ": 3.046543801631906, "Cardiac failure acute ": 4.202158128334568, "Cardiogenic shock ": 8.686976265927408, "Cardiotoxicity ": 6.771867693294144, "Clostridium difficile infection ": 5.863781155191644, "Cystitis haemorrhagic ": 6.279403976036073, "Cytokine release syndrome ": 3.2098951539082066, "Cytomegalovirus chorioretinitis ": 18.99505866791836, "Cytomegalovirus infection ": 4.08196517042233, "Cytomegalovirus infection reactivation ": 24.95663672358785, "Cytopenia ": 18.87253410947666, "Device related infection ": 5.462717866926816, "Device related sepsis ": 27.551091710468608, "Disease progression ": 6.684018804310865, "Disease recurrence ": 2.891754458033989, "Disseminated intravascular coagulation ": 2.0245072744810626, "Disturbance in social behaviour ": 33.01067978064694, "Drug ineffective ": 2.097230824386932, "Drug ineffective for unapproved indication ": 3.450920059997697, "Drug intolerance ": 2.3158942234438435, "Drug reaction with eosinophilia and systemic symptoms ": 2.72253755243984, "Drug resistance ": 4.24769533979567, "Effusion ": 76.38988928367591, "Empyema ": 50.05658309470043, "Enterococcal infection ": 34.52327111328297, "Escherichia bacteraemia ": 22.56597035148707, "Febrile neutropenia ": 8.091478180854834, "Functional gastrointestinal disorder ": 30.08609264414136, "Graft versus host disease ": 6.88856001544937, "Graft versus host disease in gastrointestinal tract ": 12.998549725714092, "Haematotoxicity ": 5.014086440832481, "Haemophagocytic lymphohistiocytosis ": 3.8214682307629415, "Hemianopia ": 25.0625688570322, "Hepatitis B reactivation ": 29.34498032691541, "Human metapneumovirus test positive ": 897.7776851889981, "Human polyomavirus infection ": 80.96896438242086, "Hypercalcaemia ": 7.89263979461127, "Hypocalcaemia ": 3.996073076073188, "Hypogammaglobulinaemia ": 24.2398337978363, "Hypoperfusion ": 110.2097281671077, "Ileus paralytic ": 8.055542746336965, "Infection ": 3.4626762145622023, "Infection reactivation ": 35.04204649299487, "Infusion related reaction ": 2.0796688567753985, "Intentional product use issue ": 2.995250424325476, "Klebsiella infection ": 33.79957877498846, "Liver disorder ": 2.8775596145840594, "Lower respiratory tract infection ": 2.107260136192868, "Lymphopenia ": 6.087349356498266, "Malignant neoplasm progression ": 2.1469346685459314, "Metapneumovirus infection ": 102.2879728018637, "Morganella infection ": 284.2395129934279, "Mucosal inflammation ": 10.07119456556988, "Multiple organ dysfunction syndrome ": 5.786790440888698, "Myelodysplastic syndrome ": 10.459418173903924, "Myelosuppression ": 5.9212924305736, "Neuralgia ": 2.86210752542952, "Neuropathy peripheral ": 12.615048916111304, "Neurotoxicity ": 5.8134152823756295, "Neutropenia ": 5.877351301898526, "Off label use ": 3.1338051085319125, "Osteonecrosis of jaw ": 6.0937859417738895, "Pancytopenia ": 4.806276840060104, "Paranoia ": 7.083730416430863, "Peripheral sensory neuropathy ": 26.60243216122796, "Plasma cell leukaemia ": 202.4132823908067, "Plasma cell myeloma ": 123.95715837787353, "Plasma cell myeloma recurrent ": 184.7513470758042, "Plasma cell myeloma refractory ": 690.6130652070248, "Plasmacytoma ": 139.77245146240406, "Platelet count decreased ": 2.2168492408265026, "Pneumonia ": 2.9477583260172757, "Pneumonia bacterial ": 8.285454616131386, "Polyneuropathy ": 25.32014122752416, "Polyomavirus-associated nephropathy ": 72.14547868530732, "Poor quality sleep ": 5.6455309832841865, "Posterior reversible encephalopathy syndrome ": 17.30020423427628, "Product use in unapproved indication ": 3.1445853076216097, "Progressive multifocal leukoencephalopathy ": 33.05804275521204, "Pulmonary hypertension ": 2.7486597628446803, "Pulmonary oedema ": 4.261555161053419, "Pulseless electrical activity ": 36.52636557711005, "Respiratory failure ": 2.36130286847538, "Respiratory tract infection ": 3.701934198328236, "Second primary malignancy ": 6.2689706562796434, "Sepsis ": 5.25327860096637, "Septic shock ": 4.768354365269039, "Shock ": 3.456845078529644, "Staphylococcal bacteraemia ": 55.40116470785328, "Staphylococcal infection ": 3.462095060056636, "Staphylococcal sepsis ": 19.992138842365183, "Therapeutic product effect incomplete ": 5.205485490624876, "Therapeutic response decreased ": 4.563276934575213, "Therapy non-responder ": 10.52700661531997, "Therapy partial responder ": 31.07916673348921, "Thrombocytopenia ": 5.309168169363848, "Thrombotic microangiopathy ": 16.775965057481343, "Thrombotic thrombocytopenic purpura ": 12.185058020817925, "Treatment failure ": 4.093463112350973, "Tumour lysis syndrome ": 25.30212047094461, "Upper gastrointestinal haemorrhage ": 5.476847539489917, "Varicella zoster virus infection ": 16.88964894513963, "Vascular device infection ": 20.45438759252028}
\ No newline at end of file
+{"Hepatitis A antibody positive": 9765.233574728178, "Hepatitis C": 86.9189159251557, "Suspected transmission of an infectious agent via product": 2056.207203755685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/186.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/186.json
index 391e4364d06..8b452700ea4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/186.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/186.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.7564731483093547, "Atrial fibrillation ": 2.0038012078612417, "Cardiac failure ": 5.970280361334661, "Cardiac failure congestive ": 2.5059774437944573, "Cardiomegaly ": 12.802095898522364, "Condition aggravated ": 4.218473327183254, "Cyanosis ": 6.182629087370977, "Disease progression ": 4.704927633410306, "Drug ineffective for unapproved indication ": 12.870863175247678, "Drug interaction ": 2.515000476448507, "Dyspepsia ": 3.4813260356856484, "Exposure during pregnancy ": 2.2915215939227864, "Fluid retention ": 7.329738405030459, "Flushing ": 2.3685452636759696, "General physical health deterioration ": 2.3440078165387006, "Haemoptysis ": 6.540342458308255, "Lung transplant ": 75.37673154476656, "Multiple organ dysfunction syndrome ": 4.439462878133713, "Off label use ": 2.4100318357968447, "Oxygen saturation decreased ": 8.379748697437957, "Product use in unapproved indication ": 2.563319699092871, "Product use issue ": 4.653239195489384, "Pulmonary arterial hypertension ": 56.80937364260403, "Pulmonary hypertension ": 35.76278630176294, "Pulmonary oedema ": 8.245813560887624, "Respiratory failure ": 5.183862866599906, "Right ventricular failure ": 98.78318907556049, "Sepsis ": 2.7686972594083707, "Therapy non-responder ": 5.790961078378302}
\ No newline at end of file
+{"Adverse event": 3.8930880723798102, "Aggression": 2.9183720884033093, "Anaemia": 27.212609499853823, "Ascites": 9.402611649064644, "Depression": 4.013447813294661, "Drug interaction": 2.847572001412493, "Dysgeusia": 6.934465018242256, "Haemoglobin decreased": 3.3490557680806483, "Haemolytic anaemia": 11.56926518439374, "Hepatic cirrhosis": 7.646238729680586, "Hepatic encephalopathy": 11.507872578266722, "Hepatic failure": 5.513339956177235, "Hepatitis C": 9.49460475171496, "Leukopenia": 9.294900266145223, "Multiple organ dysfunction syndrome": 3.90012924023044, "Neutropenia": 10.433246432874002, "Oedema peripheral": 2.395178723624129, "Pancytopenia": 5.589816312299018, "Platelet count decreased": 2.4932417112616867, "Red blood cell count decreased": 4.92110523420947, "Sepsis": 2.842931327301222, "Stomatitis": 2.082148023449525, "Taste disorder": 3.953089900554972, "Thrombocytopenia": 5.258270891114163, "Urinary tract infection": 2.0798926087033154, "Weight decreased": 4.175382113698321, "White blood cell count decreased": 2.1123775493664323}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/187.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/187.json
index 3d58cd588f4..9803c58ae06 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/187.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/187.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 4.210566486741768, "Amylase increased ": 3.89819793428598, "Arteriosclerosis ": 3.1740392819132848, "Aspartate aminotransferase increased ": 3.899898913275789, "Atrial fibrillation ": 2.221035254214039, "Blood test abnormal ": 2.656398791225277, "Bone pain ": 3.1607142444926475, "Brain fog ": 3.43538619487984, "Cardiac disorder ": 3.738463972650453, "Cardiac failure ": 2.5304443993133185, "Cardiac failure congestive ": 3.9616968463428615, "Cardiomegaly ": 2.384336105720248, "Chronic myeloid leukaemia ": 44.31738130229738, "Clostridium difficile infection ": 2.628549378272279, "Complex regional pain syndrome ": 17.375924349815794, "Constipation ": 2.982985568918867, "Cytogenetic analysis abnormal ": 61.93299498831032, "Cytopenia ": 8.93442349340159, "Dehydration ": 3.0853719706238114, "Dementia ": 2.154371009725012, "Diarrhoea ": 5.829549435725562, "Drug intolerance ": 2.92648648392141, "Drug resistance ": 2.127813673801134, "Dry skin ": 2.222251118786424, "Eating disorder ": 2.7939572289236008, "Eructation ": 3.980380618077744, "Erythema multiforme ": 2.351200422610988, "Faeces soft ": 8.588930549754554, "Feeding disorder ": 3.0241784931202704, "Flatulence ": 2.5507338799764017, "Fluid retention ": 6.942649593110662, "Full blood count abnormal ": 2.481239568516834, "Full blood count decreased ": 3.233179046733889, "Gastroenteritis viral ": 6.587175195083663, "Gastrointestinal disorder ": 2.506457409876476, "Gastrooesophageal reflux disease ": 2.293583928277473, "Gout ": 2.087145251971984, "Haemoglobin decreased ": 2.1044663464687434, "Hepatic cytolysis ": 2.179710639736524, "Hepatic enzyme increased ": 2.170667410834908, "Hepatic function abnormal ": 3.0662561213551527, "Hepatotoxicity ": 4.842737385106275, "Hernia ": 4.969237201429277, "Hyperaesthesia ": 3.0743117283482606, "Hypoacusis ": 2.228443779484894, "Illness ": 5.318224218804581, "Immune system disorder ": 2.4220157521519208, "Intervertebral disc disorder ": 16.77667193430694, "Laboratory test abnormal ": 6.593079267966624, "Leukaemia ": 3.4997137297925662, "Lipase increased ": 4.18589047240673, "Livedo reticularis ": 22.41480255799906, "Liver disorder ": 3.7584599413202393, "Liver function test increased ": 4.26626372062178, "Lumbar radiculopathy ": 49.67300396486864, "Neoplasm progression ": 13.477764058775024, "Neuropathy peripheral ": 2.0409597799959958, "Pancreatitis chronic ": 10.71252557069622, "Pericardial effusion ": 17.401747880928824, "Peripheral arterial occlusive disease ": 8.180599131483248, "Peroneal nerve palsy ": 11.528472180872493, "Philadelphia chromosome positive ": 113.38880249549912, "Platelet count decreased ": 2.1146898451377094, "Platelet count increased ": 8.311839426802559, "Pleural effusion ": 25.190130504144733, "Pneumonia ": 2.2004428466271544, "Product dose omission issue ": 2.450862325561155, "Pulmonary arterial hypertension ": 15.220031608803955, "Pulmonary hypertension ": 10.091001338829225, "Pulmonary oedema ": 10.766213735254556, "Red blood cell count decreased ": 2.492275087211099, "Renal disorder ": 3.429015322118524, "Renal impairment ": 3.570605202432416, "Second primary malignancy ": 28.95057316394313, "Sensory loss ": 3.422057776888627, "Skin ulcer ": 4.018673088317407, "Stress ": 2.7406052831799, "Transaminases increased ": 2.022107255253692, "Ulcer ": 5.0678119604874485, "Weight decreased ": 2.461932582747204, "White blood cell count abnormal ": 8.28320962830743, "White blood cell count increased ": 5.445098163171418}
\ No newline at end of file
+{"Osteonecrosis of jaw": 458.2330193518784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/188.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/188.json
index b71a78c51c7..379b84d539c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/188.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/188.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.2044212826714547, "Blast crisis in myelogenous leukaemia ": 143.83841396040518, "Blood bilirubin increased ": 4.059157401059607, "Cerebrovascular accident ": 2.5300470520843943, "Cholelithiasis ": 7.108120340755055, "Chronic myeloid leukaemia ": 189.04989839704544, "Chronic myeloid leukaemia recurrent ": 263.8626742984155, "Cytogenetic analysis abnormal ": 568.5689002458265, "Cytopenia ": 24.3944787232268, "Diarrhoea ": 2.1709021587477726, "Drug ineffective ": 2.186416907044326, "Drug intolerance ": 35.6438050223111, "Drug resistance ": 55.23884140868691, "Erythema nodosum ": 37.25654525335464, "Fluid retention ": 10.9499363878384, "Hepatic function abnormal ": 2.0651031824490067, "Hypertension ": 2.020873524020596, "Malignant neoplasm progression ": 3.751758454889652, "Muscle spasms ": 2.669409817112228, "Myocardial infarction ": 2.992635150452614, "Neoplasm progression ": 7.750563083848918, "Pancreatitis ": 10.562963266460804, "Pancytopenia ": 4.393682976373812, "Peripheral arterial occlusive disease ": 46.18491893600885, "Peripheral vascular disorder ": 17.0810309108648, "Philadelphia chromosome positive ": 350.1316962967879, "Pleural effusion ": 34.44009112692088, "Pulmonary arterial hypertension ": 14.393438293893627, "Pulmonary hypertension ": 11.502867731194586, "Renal impairment ": 3.043174614951503, "Therapeutic response decreased ": 6.532499055980485, "Therapy non-responder ": 17.121401578344823, "Thrombocytopenia ": 4.573331417024784, "Treatment failure ": 5.708643194170404, "Ulcer ": 18.545509613748127}
\ No newline at end of file
+{"Abdominal pain upper": 2.576036982290252, "Acute phase reaction": 1200.2870037727855, "Arthralgia": 2.0490172957917334, "Atypical femur fracture": 957.3265170684526, "Atypical fracture": 1262.5054649581284, "Back pain": 4.888974441123088, "Blood calcium increased": 5.643798392857228, "Blood parathyroid hormone increased": 18.091390498298043, "Bone disorder": 4.904500151741326, "Bone pain": 18.81208898325868, "Chest pain": 2.377434051531969, "Compression fracture": 22.27329326575435, "Dental caries": 6.639198397293432, "Dyspepsia": 2.550747412218436, "Ejection fraction decreased": 6.229906672438436, "Exposed bone in jaw": 165.77897804957803, "Extravasation": 16.3326894785501, "Fall": 2.630192166224598, "Femoral neck fracture": 21.062285191614023, "Femur fracture": 53.23844721348703, "Flatulence": 2.456956915383216, "Foot fracture": 2.9904376969671675, "Fracture": 6.166452749831576, "Gastric haemorrhage": 4.123335901182265, "Gastric ulcer": 2.8241725972947003, "Gastritis": 6.879406770703405, "Gingivitis": 12.047995164160998, "Groin pain": 5.077553307451468, "Hip fracture": 4.057248599655636, "Hypercalcaemia": 10.33021937226971, "Hypocalcaemia": 9.375353809534593, "Impaired healing": 3.9670913186831194, "Influenza like illness": 3.49833481901078, "Infusion site extravasation": 24.87970433586598, "Injection site extravasation": 12.000684036178717, "Jaw disorder": 25.82526582301634, "Loose tooth": 27.42327193061157, "Low turnover osteopathy": 901.5967187241832, "Lower limb fracture": 3.8275476501795023, "Movement disorder": 3.7582723028538094, "Musculoskeletal chest pain": 3.539006726393864, "Musculoskeletal pain": 4.984593009101706, "Musculoskeletal stiffness": 2.4781772130800053, "Oesophageal ulcer": 13.964751634701608, "Oesophagitis": 20.14578747238701, "Osteitis": 53.53767787315208, "Osteomyelitis": 44.95133363244908, "Osteonecrosis": 4.964407359658485, "Osteonecrosis of jaw": 500.44137319738974, "Pain in jaw": 12.582461971561989, "Pathological fracture": 29.343236651921647, "Periodontitis": 60.2509976744506, "Phlebitis": 6.178977510161345, "Product administration error": 4.1010948190622765, "Rib fracture": 3.260998281005002, "Spinal compression fracture": 11.53334467187501, "Spinal fracture": 5.619036141169437, "Spinal pain": 5.677309521948742, "Stress fracture": 74.54364290886284, "Tooth disorder": 6.1082105189143565, "Tooth extraction": 51.37317514056999, "Tooth fracture": 6.912397091587622, "Toothache": 6.53543194901932}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/189.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/189.json
index 688479c5ab6..5fedf948983 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/189.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/189.json
@@ -1 +1 @@
-{"Angioedema ": 16.02034635742221, "Aphasia ": 4.2677612393737565, "Atrioventricular septal defect ": 165.76930180517869, "Back pain ": 10.81923093934935, "Bone erosion ": 9.27105165551999, "Bradykinesia ": 20.57437389304109, "Breast cancer stage II ": 17.62389774736483, "Breast cancer stage III ": 7.2486668466569455, "Drug ineffective ": 5.67305900639578, "Drug ineffective for unapproved indication ": 73.13723531916911, "Drug intolerance ": 23.207020329253915, "Drug resistance ": 2.5934303984837475, "Dysphonia ": 33.19621117652444, "Endometriosis ": 13.42008441955809, "Exostosis ": 10.2498513317249, "Folliculitis ": 2.550730441051212, "Food intolerance ": 19.423978655216736, "Head discomfort ": 74.1577146490275, "Headache ": 2.273232320230348, "Hepatic cirrhosis ": 3.0957041641103524, "Hyperammonaemic encephalopathy ": 16.00685923621643, "Hyperhidrosis ": 7.286541101475322, "Hypersensitivity ": 7.832189868211626, "Joint stiffness ": 2.7210559583580967, "Laryngitis ": 9.51388159013472, "Lennox-Gastaut syndrome ": 195.5232187538583, "Lip dry ": 10.936227848000453, "Lower limb fracture ": 4.285149736620262, "Lupus vulgaris ": 49.29371591454608, "Mastoiditis ": 85.07329063963378, "Migraine ": 28.4761202693563, "Migraine with aura ": 18.85873440850666, "Mood altered ": 3.187024307882343, "Myoclonic epilepsy ": 20.20744794153688, "Myoclonus ": 2.5296490852367497, "Neck pain ": 29.085627103859597, "Nephrolithiasis ": 36.43819102619504, "Nightmare ": 43.24589284850268, "Off label use ": 8.275080026400827, "Orthostatic hypotension ": 2.2681518838587995, "Otitis media ": 19.618845686512465, "Pain ": 3.704221710221257, "Paranasal cyst ": 217.6383795944915, "Petit mal epilepsy ": 5.881226829385805, "Product use in unapproved indication ": 16.641283762609625, "Product used for unknown indication ": 90.84680576452529, "Sedation ": 78.85142360540652, "Stress ": 3.515337933710041, "Swelling face ": 23.827523545243032, "Swollen tongue ": 42.79880261636546, "Therapeutic product effect incomplete ": 3.913267650956037, "Therapeutic response decreased ": 2.9826001453295845, "Therapy non-responder ": 3.487984772207718, "Therapy partial responder ": 6.339146741001509, "Treatment failure ": 5.215984440898126, "Vascular malformation ": 140.1788960645248, "Visual field defect ": 5.700475956517559}
\ No newline at end of file
+{"Abdominal abscess": 39.64266638877553, "Abnormal behaviour": 3.433742445346988, "Acute lymphocytic leukaemia": 28.993445463826863, "Acute myeloid leukaemia": 5.891836545351418, "Acute respiratory distress syndrome": 3.196000370771182, "Amyloidosis": 25.58679349938668, "Anaemia": 2.41810699861508, "Ascites": 3.767389091003765, "Aspergillus infection": 6.431472475851303, "Atelectasis": 13.363535612506402, "Bacteraemia": 6.7030803846941245, "Bacterial sepsis": 13.62871952846341, "Brain fog": 3.80838561950461, "Brain oedema": 5.656948749195101, "Bronchopulmonary aspergillosis": 10.512663891943696, "Candida infection": 10.194915393785427, "Cardiac failure": 3.0462653870219114, "Cardiac failure acute": 4.202158128334568, "Cardiogenic shock": 8.686976265927408, "Cardiotoxicity": 6.771867693294144, "Clostridium difficile infection": 5.863781155191644, "Cystitis haemorrhagic": 6.279403976036073, "Cytokine release syndrome": 3.2098951539082066, "Cytomegalovirus chorioretinitis": 18.99505866791836, "Cytomegalovirus infection": 4.08196517042233, "Cytomegalovirus infection reactivation": 24.95663672358785, "Cytopenia": 18.857400337373917, "Device related infection": 5.462717866926816, "Device related sepsis": 27.551091710468608, "Disease progression": 6.684018804310865, "Disease recurrence": 2.891754458033989, "Disseminated intravascular coagulation": 2.0245072744810626, "Disturbance in social behaviour": 32.96847395438122, "Drug ineffective": 2.09721530765359, "Drug ineffective for unapproved indication": 3.450920059997697, "Drug intolerance": 2.3158942234438435, "Drug reaction with eosinophilia and systemic symptoms": 2.7223125418741123, "Drug resistance": 4.24769533979567, "Effusion": 76.38988928367591, "Empyema": 50.05658309470043, "Enterococcal infection": 34.52327111328297, "Escherichia bacteraemia": 22.56597035148707, "Febrile neutropenia": 8.091478180854834, "Functional gastrointestinal disorder": 30.08609264414136, "Graft versus host disease": 6.88856001544937, "Graft versus host disease in gastrointestinal tract": 12.998549725714092, "Haematotoxicity": 5.014086440832481, "Haemophagocytic lymphohistiocytosis": 3.8214682307629415, "Hemianopia": 25.0625688570322, "Hepatitis B reactivation": 29.34498032691541, "Human metapneumovirus test positive": 897.7776851889981, "Human polyomavirus infection": 80.96896438242086, "Hypercalcaemia": 7.89263979461127, "Hypocalcaemia": 3.996073076073188, "Hypogammaglobulinaemia": 24.2398337978363, "Hypoperfusion": 110.2097281671077, "Ileus paralytic": 8.055542746336965, "Infection": 3.4626762145622023, "Infection reactivation": 35.04204649299487, "Infusion related reaction": 2.0796688567753985, "Intentional product use issue": 2.995250424325476, "Klebsiella infection": 33.79957877498846, "Liver disorder": 2.8775596145840594, "Lower respiratory tract infection": 2.107260136192868, "Lymphopenia": 6.087349356498266, "Malignant neoplasm progression": 2.1469346685459314, "Metapneumovirus infection": 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"Polyomavirus-associated nephropathy": 72.14547868530732, "Poor quality sleep": 5.6455309832841865, "Posterior reversible encephalopathy syndrome": 17.30020423427628, "Product use in unapproved indication": 3.144487117850824, "Progressive multifocal leukoencephalopathy": 33.05804275521204, "Pulmonary hypertension": 2.7486597628446803, "Pulmonary oedema": 4.260994729700002, "Pulseless electrical activity": 36.52636557711005, "Respiratory failure": 2.3611077501492828, "Respiratory tract infection": 3.701934198328236, "Second primary malignancy": 6.2689706562796434, "Sepsis": 5.25327860096637, "Septic shock": 4.768354365269039, "Shock": 3.456845078529644, "Staphylococcal bacteraemia": 55.40116470785328, "Staphylococcal infection": 3.462095060056636, "Staphylococcal sepsis": 19.992138842365183, "Therapeutic product effect incomplete": 5.205485490624876, "Therapeutic response decreased": 4.563276934575213, "Therapy non-responder": 10.52608279075717, "Therapy partial responder": 31.07916673348921, "Thrombocytopenia": 5.308667594084201, "Thrombotic microangiopathy": 16.775965057481343, "Thrombotic thrombocytopenic purpura": 12.185058020817925, "Treatment failure": 4.093463112350973, "Tumour lysis syndrome": 25.30212047094461, "Upper gastrointestinal haemorrhage": 5.4753576457324655, "Varicella zoster virus infection": 16.88964894513963, "Vascular device infection": 20.45438759252028}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/19.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/19.json
index 50ee6b3dacc..f4e8721aa0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/19.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/19.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.92553289480419, "Alanine aminotransferase abnormal ": 94.10219370372036, "Arthritis ": 8.015668489391434, "Atrial fibrillation ": 3.9002260637323785, "Blood pressure abnormal ": 16.221155519769955, "Blood pressure diastolic abnormal ": 126.10292480836006, "Blood pressure diastolic decreased ": 42.824865341921225, "Blood pressure fluctuation ": 10.003419313012758, "Blood pressure systolic abnormal ": 128.3011620091081, "Blood pressure systolic increased ": 12.809967703396197, "Bone density abnormal ": 26.54421966391294, "Bone pain ": 5.057622175263924, "Bronchitis ": 6.872485800774938, "C-reactive protein increased ": 4.508806645776192, "Carpal tunnel syndrome ": 30.76741645086172, "Cystocele ": 208.705853387233, "Disease recurrence ": 10.52068280893208, "Drug interaction ": 2.6725078114305005, "Drug withdrawal syndrome ": 5.578997902856047, "Feeling cold ": 3.069383043430526, "Fibromyalgia ": 11.566126105421327, "Gait disturbance ": 2.719988534161316, "General physical health deterioration ": 3.7396188839798192, "Heart rate decreased ": 7.617924085514173, "Hepatic enzyme increased ": 2.8789150738840488, "Hepatitis ": 5.182508495608797, "Hypersensitivity ": 2.3373591013416632, "Hypokinesia ": 11.31175437897931, "Inflammation ": 3.3921359423737103, "Infusion related reaction ": 3.4797199909375998, "Injection site bruising ": 13.30794375957594, "Injection site haemorrhage ": 14.555397313196542, "Joint swelling ": 2.5442527299246827, "Limb injury ": 12.253353225594433, "Limb mass ": 62.08834775715734, "Liver function test abnormal ": 12.716323075861728, "Musculoskeletal pain ": 5.539037358927272, "Neuropathy peripheral ": 3.2670843270643526, "Oral herpes ": 11.519342555804696, "Osteitis ": 83.46835268608572, "Osteoarthritis ": 8.714316233681705, "Osteomyelitis ": 17.399752673986765, "Osteonecrosis of jaw ": 48.64531299490949, "Osteopenia ": 6.537883717501369, "Osteoporosis ": 3.124835017382656, "Pain ": 2.3953645926889715, "Pericarditis ": 3.342855518431429, "Pleural effusion ": 4.006768957930272, "Poor venous access ": 191.3726483021597, "Procedural pain ": 28.83017076200957, "Rectal prolapse ": 225.0546184347296, "Red blood cell sedimentation rate abnormal ": 62.00997749526741, "Rheumatoid arthritis ": 6.655821182683525, "Sinus tachycardia ": 11.970369250518496, "Sleep disorder ": 2.056634791318324, "Spinal stenosis ": 27.86975414761918, "Stress ": 6.108713715741348, "Thermal burn ": 42.750243205747225, "Vitamin D decreased ": 53.85487049570725}
\ No newline at end of file
+{"Coma": 189.14256591198043, "Gastrooesophageal reflux disease": 188.6548206410751, "Pneumonia aspiration": 553.088874749223, "Somnolence": 46.77192552422103}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/190.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/190.json
index 3769942434a..c66d71fddf8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/190.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/190.json
@@ -1 +1 @@
-{"Acne ": 3.6249476135339824, "Adrenal insufficiency ": 2.622236908451458, "Amylase increased ": 4.011982399454651, "Blood creatine phosphokinase increased ": 2.787053910458048, "Brain neoplasm ": 7.443312610076406, "Brain oedema ": 3.029499074691308, "Brain operation ": 31.109559251423097, "Carcinoembryonic antigen increased ": 13.05382402111739, "Cardiac dysfunction ": 10.987264599353784, "Central serous chorioretinopathy ": 22.94528027908625, "Cholestasis ": 2.4387481631134635, "Chorioretinitis ": 27.53591418825309, "Colitis ": 7.346358293903327, "Colitis ischaemic ": 3.2573631848021267, "Cystoid macular oedema ": 27.702178957664, "Death ": 10.07322255904154, "Decreased appetite ": 2.4815546485938342, "Dehydration ": 3.568813214881859, "Dermatitis acneiform ": 35.456894439896715, "Detachment of retinal pigment epithelium ": 80.95807066782193, "Diarrhoea ": 2.087179551212312, "Diarrhoea haemorrhagic ": 2.236318881032428, "Disease progression ": 2.041966325611828, "Dry skin ": 2.3646452371718434, "Ejection fraction decreased ": 4.425536664978186, "Electrocardiogram QT prolonged ": 2.27160784387858, "Encephalitis ": 2.698300949610533, "Enteritis infectious ": 20.562960322257915, "Enterocolitis ": 9.463731640467063, "Eye disorder ": 4.897555542825799, "Eye symptom ": 50.00329232035875, "Feeding disorder ": 3.285153783662985, "Foreign body in throat ": 6.902869377386941, "Haematochezia ": 2.506617132214196, "Hepatic cytolysis ": 4.542024099430119, "Hernia ": 2.599225140507091, "Hypoacusis ": 3.5123686237946736, "Hypomagnesaemia ": 4.4677448413371055, "Hypophysitis ": 5.755737250224573, "Ileus ": 5.136208007165405, "Illness ": 2.985956947198102, "Immune-mediated enterocolitis ": 15.094653764235456, "Immune-mediated hepatic disorder ": 15.801275667181104, "Interstitial lung disease ": 2.257630343041064, "Intestinal obstruction ": 5.950092364101555, "Intestinal perforation ": 4.20298303462268, "Iridocyclitis ": 10.024771499229317, "Iron deficiency anaemia ": 3.648760396908065, "Large intestinal ulcer ": 37.64028857281047, "Lentigo ": 78.7446942258701, "Lipase increased ": 2.835657183522277, "Liver disorder ": 4.004724307976833, "Macular detachment ": 138.08795302806917, "Macular oedema ": 13.476829963000965, "Malignant melanoma ": 3.245991038295499, "Malignant neoplasm progression ": 2.8503229898888818, "Melaena ": 2.2814799737424134, "Melanocytic naevus ": 30.444162681138355, "Meningitis aseptic ": 3.761054922071707, "Metastases to central nervous system ": 2.738881113488303, "Metastatic malignant melanoma ": 18.72576582039307, "Myositis ": 2.126588931767969, "Neoplasm progression ": 41.482383360703295, "Neoplasm recurrence ": 9.368481757081865, "Nocturia ": 2.6676686233640123, "Off label use ": 8.130775327355192, "Palmar-plantar erythrodysaesthesia syndrome ": 2.154090941186156, "Pancreatitis acute ": 2.0701855016824218, "Paronychia ": 9.72228291733152, "Photosensitivity reaction ": 2.1245148090462034, "Polyneuropathy ": 2.93020532691351, "Product dose omission issue ": 2.332951615734432, "Product physical issue ": 6.193438917247973, "Product prescribing error ": 4.166942773383198, "Product use complaint ": 10.699173929674076, "Product use in unapproved indication ": 14.869115764167327, "Rectal haemorrhage ": 2.3203354058294963, "Renal disorder ": 2.425954542325994, "Renal impairment ": 2.7166103437945743, "Retinal detachment ": 23.58744299445615, "Retinal oedema ": 40.14540824223618, "Retinopathy ": 6.761030131442941, "Second primary malignancy ": 29.646028287291344, "Serous retinal detachment ": 1164.8285590885182, "Serous retinopathy ": 1040.8470898482908, "Skin disorder ": 2.0491935620544086, "Skin fissures ": 4.60250612929561, "Skin hyperpigmentation ": 5.37626273244945, "Skin papilloma ": 10.492121021974182, "Small intestinal obstruction ": 4.056177116693562, "Squamous cell carcinoma ": 4.804410649424433, "Subretinal fluid ": 32.242377527463496, "Therapy interrupted ": 2.5810145777291447, "Tumour haemorrhage ": 7.010344678232548, "Tumour lysis syndrome ": 5.508474163760502, "Underdose ": 7.040338454135608, "Uveitis ": 22.6732421501873, "Vision blurred ": 3.574438113771456, "Visual acuity reduced ": 2.335364373805172, "Visual impairment ": 3.2075703988200104, "Vitiligo ": 5.381217776298687, "Vitreous floaters ": 3.8117590166578816}
\ No newline at end of file
+{"Abdominal distension": 2.7564731483093547, "Atrial fibrillation": 2.0037465152945813, "Cardiac failure": 5.969735185110169, "Cardiac failure congestive": 2.5057879444505504, "Cardiomegaly": 12.802095898522364, "Condition aggravated": 4.218473327183254, "Cyanosis": 6.181475762612402, "Disease progression": 4.704927633410306, "Drug ineffective for unapproved indication": 12.870863175247678, "Drug interaction": 2.515000476448507, "Dyspepsia": 3.4813260356856484, "Exposure during pregnancy": 2.2915215939227864, "Fluid retention": 7.329738405030459, "Flushing": 2.3685452636759696, "General physical health deterioration": 2.3440078165387006, "Haemoptysis": 6.540342458308255, "Lung transplant": 75.37673154476656, "Multiple organ dysfunction syndrome": 4.439462878133713, "Off label use": 2.4099368984465963, "Oxygen saturation decreased": 8.379300098464256, "Product use in unapproved indication": 2.563239755144085, "Product use issue": 4.653239195489384, "Pulmonary arterial hypertension": 56.80937364260403, "Pulmonary hypertension": 35.76278630176294, "Pulmonary oedema": 8.244730395300698, "Respiratory failure": 5.183434755971006, "Right ventricular failure": 98.78318907556049, "Sepsis": 2.7686972594083707, "Therapy non-responder": 5.790455114399161}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/191.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/191.json
index c963e58c702..94748748b6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/191.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/191.json
@@ -1 +1 @@
-{"Anaemia ": 2.677646493652403, "Disease progression ": 7.748357525772231, "Drug ineffective ": 2.0253043112566247, "Febrile neutropenia ": 22.86711427181714, "Hodgkin's disease ": 509.8437675637159, "Malignant neoplasm progression ": 12.169908275871409, "Myelosuppression ": 15.995376106483372, "Neuropathy peripheral ": 8.202021440140475, "Neutropenia ": 7.855211256921048, "Neutrophil count decreased ": 12.804708737605784, "Off label use ": 3.408813195096497, "Product use in unapproved indication ": 4.628148035202643, "Thrombocytopenia ": 2.928931560339056, "White blood cell count decreased ": 11.319192895109182}
\ No newline at end of file
+{"Alanine aminotransferase increased": 4.210566486741768, "Amylase increased": 3.89819793428598, "Arteriosclerosis": 3.1740392819132848, "Aspartate aminotransferase increased": 3.899898913275789, "Atrial fibrillation": 2.220974573636131, "Blood test abnormal": 2.656398791225277, "Bone pain": 3.1607142444926475, "Brain fog": 3.43538619487984, "Cardiac disorder": 3.738463972650453, "Cardiac failure": 2.5302131757891733, "Cardiac failure congestive": 3.9613967168217856, "Cardiomegaly": 2.384336105720248, "Chronic myeloid leukaemia": 44.31738130229738, "Clostridium difficile infection": 2.628549378272279, "Complex regional pain syndrome": 17.375924349815794, "Constipation": 2.982985568918867, "Cytogenetic analysis abnormal": 61.93299498831032, "Cytopenia": 8.927289441275837, "Dehydration": 3.085207058054461, "Dementia": 2.154371009725012, "Diarrhoea": 5.82950064803432, "Drug intolerance": 2.92648648392141, "Drug resistance": 2.127813673801134, "Dry skin": 2.222251118786424, "Eating disorder": 2.7939572289236008, "Eructation": 3.980380618077744, "Erythema multiforme": 2.351200422610988, "Faeces soft": 8.588930549754554, "Feeding disorder": 3.0241784931202704, "Flatulence": 2.550526363235168, "Fluid retention": 6.942649593110662, "Full blood count abnormal": 2.481239568516834, "Full blood count decreased": 3.233179046733889, "Gastroenteritis viral": 6.587175195083663, "Gastrointestinal disorder": 2.506378406639428, "Gastrooesophageal reflux disease": 2.293583928277473, "Gout": 2.087145251971984, "Haemoglobin decreased": 2.1044663464687434, "Hepatic cytolysis": 2.179710639736524, "Hepatic enzyme increased": 2.170667410834908, "Hepatic function abnormal": 3.0662561213551527, "Hepatotoxicity": 4.842737385106275, "Hernia": 4.969237201429277, "Hyperaesthesia": 3.0743117283482606, "Hypoacusis": 2.2282561587304284, "Illness": 5.318224218804581, "Immune system disorder": 2.4220157521519208, "Intervertebral disc disorder": 16.77667193430694, "Laboratory test abnormal": 6.593079267966624, "Leukaemia": 3.4997137297925662, "Lipase increased": 4.18589047240673, "Livedo reticularis": 22.41480255799906, "Liver disorder": 3.7584599413202393, "Liver function test increased": 4.26626372062178, "Lumbar radiculopathy": 49.67300396486864, "Neoplasm progression": 13.477764058775024, "Neuropathy peripheral": 2.0408977702062776, "Pancreatitis chronic": 10.71252557069622, "Pericardial effusion": 17.401747880928824, "Peripheral arterial occlusive disease": 8.180599131483248, "Peroneal nerve palsy": 11.528472180872493, "Philadelphia chromosome positive": 113.38880249549912, "Platelet count decreased": 2.1146898451377094, "Platelet count increased": 8.311839426802559, "Pleural effusion": 25.18778220443744, "Pneumonia": 2.2004428466271544, "Product dose omission issue": 2.450862325561155, "Pulmonary arterial hypertension": 15.220031608803955, "Pulmonary hypertension": 10.091001338829225, "Pulmonary oedema": 10.764792796666097, "Red blood cell count decreased": 2.492275087211099, "Renal disorder": 3.428508803633493, "Renal impairment": 3.570605202432416, "Second primary malignancy": 28.95057316394313, "Sensory loss": 3.422057776888627, "Skin ulcer": 4.018673088317407, "Stress": 2.7406052831799, "Transaminases increased": 2.021983342538597, "Ulcer": 5.0678119604874485, "Weight decreased": 2.461932582747204, "White blood cell count abnormal": 8.28320962830743, "White blood cell count increased": 5.444052942759177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/192.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/192.json
index 5be0d5e1102..54a7f35c03e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/192.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/192.json
@@ -1 +1 @@
-{"Chronic obstructive pulmonary disease ": 141.20322855998197, "Pneumonia ": 11.132844809588155}
\ No newline at end of file
+{"Abdominal pain": 2.16380810541848, "Blast crisis in myelogenous leukaemia": 141.19117004321186, "Blood bilirubin increased": 3.984450331893605, "Cerebrovascular accident": 2.4834131726953013, "Cholelithiasis": 6.977298447405228, "Chronic myeloid leukaemia": 185.56609482816117, "Chronic myeloid leukaemia recurrent": 259.00653254342683, "Cytogenetic analysis abnormal": 558.0943125641259, "Cytopenia": 23.926246810203384, "Diarrhoea": 2.130850136455247, "Drug ineffective": 2.14607247198952, "Drug intolerance": 34.98530510757389, "Drug resistance": 54.21982733756069, "Erythema nodosum": 36.57081019828801, "Fluid retention": 10.748311252494018, "Hepatic function abnormal": 2.0270932351026434, "Malignant neoplasm progression": 3.682652636205566, "Muscle spasms": 2.6202544204659968, "Myocardial infarction": 2.9375196575679707, "Neoplasm progression": 7.607856672508886, "Pancreatitis": 10.368311083845008, "Pancytopenia": 4.312789140253176, "Peripheral arterial occlusive disease": 45.33485123398948, "Peripheral vascular disorder": 16.766662244673572, "Philadelphia chromosome positive": 343.68706501491647, "Pleural effusion": 33.80146747754347, "Pulmonary arterial hypertension": 14.128533477436848, "Pulmonary hypertension": 11.291134283732966, "Renal impairment": 2.9871394840546275, "Therapeutic response decreased": 6.412247663861899, "Therapy non-responder": 16.804563295230718, "Thrombocytopenia": 4.488620212163164, "Treatment failure": 5.603527813298479, "Ulcer": 18.204187933751985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/193.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/193.json
index 1d8c9118db7..b14def2e23d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/193.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/193.json
@@ -1 +1 @@
-{"Blood pressure decreased ": 9.944783703212, "Chest discomfort ": 2.948200604974316, "Dissociation ": 461.80251896243504, "Drug ineffective ": 3.8950456309289136, "Drug interaction ": 3.3219555573638004, "Electrocardiogram QT prolonged ": 9.149609123764314, "Hypomania ": 238.816437624049, "Mental disorder ": 33.24999593428197, "Off label use ": 5.778510015499896, "Schizophrenia ": 192.80771390351524, "Suicidal ideation ": 15.985482624953669, "Tardive dyskinesia ": 86.4079128185948, "Weight increased ": 3.382896809196199, "Withdrawal syndrome ": 36.616543468221806}
\ No newline at end of file
+{"Angioedema": 16.004683432179913, "Aphasia": 4.262958088804281, "Atrioventricular septal defect": 165.60745408303833, "Back pain": 10.80864973072492, "Bone erosion": 9.262000062557382, "Bradykinesia": 20.55428470215011, "Breast cancer stage II": 17.60669104865008, "Breast cancer stage III": 7.241589764158109, "Drug ineffective": 5.667464696991417, "Drug ineffective for unapproved indication": 73.06573504042285, "Drug intolerance": 23.18432421803139, "Drug resistance": 2.5908981937930244, "Dysphonia": 33.163754844743295, "Endometriosis": 13.40698224446131, "Exostosis": 10.239844109786985, "Folliculitis": 2.5482400879789493, "Food intolerance": 19.40501386318629, "Head discomfort": 74.08518967532446, "Headache": 2.2753699675209584, "Hepatic cirrhosis": 3.0926817373746704, "Hyperammonaemic encephalopathy": 15.99123185732148, "Hyperhidrosis": 7.279417403782223, "Hypersensitivity": 7.824532238669058, "Joint stiffness": 2.7183993115323317, "Laryngitis": 9.504592915624944, "Lennox-Gastaut syndrome": 195.3323345656717, "Lip dry": 10.925550497971017, "Lower limb fracture": 4.2809660198862645, "Lupus vulgaris": 49.24558927342191, "Mastoiditis": 84.99022421937867, "Migraine": 28.448258653596724, "Migraine with aura": 18.840319889918277, "Mood altered": 3.183912722646456, "Myoclonic epilepsy": 20.187719568132533, "Myoclonus": 2.5271794036805773, "Neck pain": 29.057180953638422, "Nephrolithiasis": 36.396485351760944, "Nightmare": 43.20361394044385, "Off label use": 8.266655085863723, "Orthostatic hypotension": 2.265449618361581, "Otitis media": 19.599689488286455, "Pain": 3.7005673753035686, "Paranasal cyst": 217.42587868079025, "Petit mal epilepsy": 5.875485024331357, "Product use in unapproved indication": 16.62448329640936, "Product used for unknown indication": 90.75811343070016, "Sedation": 78.7743295756959, "Stress": 3.511905346801957, "Swelling face": 23.804227397927736, "Swollen tongue": 42.75695870801707, "Therapeutic product effect incomplete": 3.909445526748856, "Therapeutic response decreased": 2.97968779389072, "Therapy non-responder": 3.484274300572725, "Therapy partial responder": 6.332957648550714, "Treatment failure": 5.2108896768913935, "Vascular malformation": 140.04202490233183, "Visual field defect": 5.694910231637087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/194.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/194.json
index 5626362ddb8..ae181f13844 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/194.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/194.json
@@ -1 +1 @@
-{"Cytokine release syndrome ": 794.6843891100432, "Decreased appetite ": 3.2002757513401945, "Haemoglobin decreased ": 7.330781152975114, "Immune effector cell-associated neurotoxicity syndrome ": 497.375138176136, "Malignant neoplasm progression ": 11.064216574603396, "Neurotoxicity ": 107.81329337021144, "Platelet count decreased ": 8.313159966355384, "White blood cell count decreased ": 4.661951063207062}
\ No newline at end of file
+{"Acne": 3.6249476135339824, "Adrenal insufficiency": 2.622236908451458, "Amylase increased": 4.011982399454651, "Blood creatine phosphokinase increased": 2.787053910458048, "Brain neoplasm": 7.443312610076406, "Brain oedema": 3.029499074691308, "Brain operation": 31.109559251423097, "Carcinoembryonic antigen increased": 13.05382402111739, "Cardiac dysfunction": 10.987264599353784, "Central serous chorioretinopathy": 22.94528027908625, "Cholestasis": 2.4387481631134635, "Chorioretinitis": 27.53591418825309, "Colitis": 7.346358293903327, "Colitis ischaemic": 3.2573631848021267, "Cystoid macular oedema": 27.702178957664, "Death": 10.07322255904154, "Decreased appetite": 2.481530539621952, "Dehydration": 3.568622288381136, "Dermatitis acneiform": 35.456894439896715, "Detachment of retinal pigment epithelium": 80.95807066782193, "Diarrhoea": 2.087162109355306, "Diarrhoea haemorrhagic": 2.236318881032428, "Disease progression": 2.041966325611828, "Dry skin": 2.3646452371718434, "Ejection fraction decreased": 4.425536664978186, "Electrocardiogram QT prolonged": 2.27160784387858, "Encephalitis": 2.698300949610533, "Enteritis infectious": 20.562960322257915, "Enterocolitis": 9.463731640467063, "Eye disorder": 4.897555542825799, "Eye symptom": 50.00329232035875, "Feeding disorder": 3.285153783662985, "Foreign body in throat": 6.902869377386941, "Haematochezia": 2.506368910245721, "Hepatic cytolysis": 4.542024099430119, "Hernia": 2.599225140507091, "Hypoacusis": 3.512072497298039, "Hypomagnesaemia": 4.4677448413371055, "Hypophysitis": 5.755737250224573, "Ileus": 5.136208007165405, "Illness": 2.985956947198102, "Immune-mediated enterocolitis": 15.094653764235456, "Immune-mediated hepatic disorder": 15.801275667181104, "Interstitial lung disease": 2.257630343041064, "Intestinal obstruction": 5.950092364101555, "Intestinal perforation": 4.20298303462268, "Iridocyclitis": 10.024771499229317, "Iron deficiency anaemia": 3.6474639324354015, "Large intestinal ulcer": 37.64028857281047, "Lentigo": 78.7446942258701, "Lipase increased": 2.835657183522277, "Liver disorder": 4.004724307976833, "Macular detachment": 138.08795302806917, "Macular oedema": 13.476829963000965, "Malignant melanoma": 3.245991038295499, "Malignant neoplasm progression": 2.8503229898888818, "Melaena": 2.2811854682211963, "Melanocytic naevus": 30.444162681138355, "Meningitis aseptic": 3.761054922071707, "Metastases to central nervous system": 2.738881113488303, "Metastatic malignant melanoma": 18.72576582039307, "Myositis": 2.126588931767969, "Neoplasm progression": 41.482383360703295, "Neoplasm recurrence": 9.368481757081865, "Nocturia": 2.6676686233640123, "Off label use": 8.13045334757415, "Palmar-plantar erythrodysaesthesia syndrome": 2.154090941186156, "Pancreatitis acute": 2.0701855016824218, "Paronychia": 9.72228291733152, "Photosensitivity reaction": 2.1245148090462034, "Polyneuropathy": 2.93020532691351, "Product dose omission issue": 2.332951615734432, "Product physical issue": 6.193438917247973, "Product prescribing error": 4.166942773383198, "Product use complaint": 10.699173929674076, "Product use in unapproved indication": 14.86864743712768, "Rectal haemorrhage": 2.3203354058294963, "Renal disorder": 2.425596215502721, "Renal impairment": 2.7166103437945743, "Retinal detachment": 23.58744299445615, "Retinal oedema": 40.14540824223618, "Retinopathy": 6.761030131442941, "Second primary malignancy": 29.646028287291344, "Serous retinal detachment": 1164.8285590885182, "Serous retinopathy": 1040.8470898482908, "Skin disorder": 2.0491935620544086, "Skin fissures": 4.60250612929561, "Skin hyperpigmentation": 5.37626273244945, "Skin papilloma": 10.492121021974182, "Small intestinal obstruction": 4.056177116693562, "Squamous cell carcinoma": 4.804410649424433, "Subretinal fluid": 32.242377527463496, "Therapy interrupted": 2.5810145777291447, "Tumour haemorrhage": 7.010344678232548, "Tumour lysis syndrome": 5.508474163760502, "Underdose": 7.040338454135608, "Uveitis": 22.6732421501873, "Vision blurred": 3.574438113771456, "Visual acuity reduced": 2.335364373805172, "Visual impairment": 3.2075703988200104, "Vitiligo": 5.381217776298687, "Vitreous floaters": 3.8117590166578816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/195.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/195.json
index a0d52c0a0bf..ef9829eab77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/195.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/195.json
@@ -1 +1 @@
-{"Acute generalised exanthematous pustulosis ": 3.699357446072573, "Acute pulmonary oedema ": 18.01519279076917, "Acute respiratory failure ": 3.0509221317403896, "Adverse event ": 4.02970426153338, "Airway complication of anaesthesia ": 177.21617286771666, "Airway peak pressure increased ": 229.82135865159088, "Anaesthetic complication ": 31.648858202284764, "Anaphylactic reaction ": 48.95944933705384, "Anaphylactic shock ": 62.63059390038672, "Anaphylactoid reaction ": 44.80322535895784, "Anaphylactoid shock ": 36.34403319582919, "Angioedema ": 2.566544524063437, "Apnoea ": 10.293039919551331, "Arteriospasm coronary ": 41.88225720413606, "Aspiration ": 5.075995958779927, "Atrioventricular block ": 3.552249041341651, "Atrioventricular block complete ": 19.166788552108677, "Atrioventricular block second degree ": 16.316887435279643, "Blood pressure decreased ": 21.074956304267943, "Blood pressure systolic decreased ": 6.363081158175907, "Bradycardia ": 38.41641357843466, "Bronchospasm ": 55.96646119030744, "Cardiac arrest ": 23.45584766933434, "Cardio-respiratory arrest ": 6.101355923426213, "Cholestatic liver injury ": 24.540700753929915, "Circulatory collapse ": 4.7818131768192895, "Cyanosis ": 4.184890752666892, "Deafness neurosensory ": 7.270561107986666, "Delayed recovery from anaesthesia ": 37.42896680879122, "Depressed level of consciousness ": 3.628068049070933, "Disseminated intravascular coagulation ": 2.0630694988894915, "Drug hypersensitivity ": 3.659927077364237, "Drug reaction with eosinophilia and systemic symptoms ": 2.77440204496636, "Electrocardiogram ST segment depression ": 22.268281228545906, "Electrocardiogram ST segment elevation ": 13.92436478598933, "Endotracheal intubation ": 45.79241209800414, "Endotracheal intubation complication ": 122.43583855633123, "Erythema ": 5.042629497131584, "Extra dose administered ": 7.008260246426186, "Eyelid oedema ": 13.407298915818965, "Face oedema ": 2.453518747916452, "Flushing ": 3.530232649860551, "Haemodynamic instability ": 7.328419186327952, "Heart rate decreased ": 4.840274743219678, "Hypersensitivity ": 3.0813726860839408, "Hypertensive crisis ": 5.793747311306176, "Hypotension ": 7.282716285921468, "Hypothermia ": 5.1660197713440015, "Hypotonia ": 2.6330147698831903, "Hypoventilation ": 65.10665512450535, "Hypoxia ": 11.732621449064451, "Hypoxic-ischaemic encephalopathy ": 19.799852917211773, "Incorrect dose administered ": 4.576765028236026, "Intensive care ": 20.36594354562773, "Kounis syndrome ": 197.39885357939272, "Laryngeal oedema ": 6.82982355841586, "Laryngospasm ": 87.2436962135678, "Lip oedema ": 3.617718833455508, "Maternal exposure during delivery ": 11.927981808903398, "Mechanical ventilation ": 22.86680617419127, "Movement disorder ": 2.127181872881548, "Muscle rigidity ": 7.334475203592546, "Muscle twitching ": 2.3660244586563715, "Negative pressure pulmonary oedema ": 354.81312716219105, "Neuromuscular block prolonged ": 287.7867726350917, "Normochromic normocytic anaemia ": 18.677798859335425, "Obstructive airways disorder ": 4.785719336500796, "Oxygen saturation decreased ": 15.043253080145272, "Papule ": 2.642705488493004, "Paralysis ": 5.215729583354633, "Pharyngeal oedema ": 6.427581111025683, "Pneumothorax ": 4.496556945590275, "Post procedural haemorrhage ": 8.741206586779095, "Prinzmetal angina ": 51.033546921024985, "Procedural nausea ": 60.408463051357, "Procedural vomiting ": 94.8049991961705, "Product administered to patient of inappropriate age ": 15.29805648294015, "Product quality issue ": 2.44255953154262, "Product storage error ": 2.182568284615693, "Product use issue ": 2.319835937484415, "Pulmonary oedema ": 8.729463476304744, "Pulseless electrical activity ": 52.31824740364951, "Recurrence of neuromuscular blockade ": 7064.441157482105, "Respiratory arrest ": 19.379620631153827, "Respiratory depression ": 6.538619963583229, "Respiratory disorder ": 2.1232046876738657, "Respiratory failure ": 3.797131711417471, "Resuscitation ": 17.914354974929932, "Shock ": 5.306605193289111, "Sinus arrest ": 12.18447378508978, "Sinus tachycardia ": 3.4081481656065704, "Supraventricular tachycardia ": 12.381290588296403, "Swelling of eyelid ": 3.498537152878082, "Tachycardia ": 3.1040630753613803, "Therapeutic product effect delayed ": 17.859906269226983, "Therapeutic product effect incomplete ": 2.1194846167129024, "Tongue oedema ": 3.0040916574661995, "Type I hypersensitivity ": 29.990195779020286, "Underdose ": 7.1574894919712015, "Upper airway obstruction ": 32.20391208796593, "Urticaria ": 3.9003159958816656, "Ventricular extrasystoles ": 3.839433302629269, "Ventricular fibrillation ": 16.16556455257251, "Ventricular tachycardia ": 7.08459421881965, "Wheezing ": 3.979043850495192, "Wrong product administered ": 2.595517953807057}
\ No newline at end of file
+{"Anaemia": 2.677646493652403, "Disease progression": 7.748357525772231, "Drug ineffective": 2.025289340262884, "Febrile neutropenia": 22.86711427181714, "Hodgkin's disease": 509.8437675637159, "Malignant neoplasm progression": 12.169908275871409, "Myelosuppression": 15.995376106483372, "Neuropathy peripheral": 8.201772453147138, "Neutropenia": 7.854873455410424, "Neutrophil count decreased": 12.804708737605784, "Off label use": 3.408678935475385, "Product use in unapproved indication": 4.628003716095495, "Thrombocytopenia": 2.928656063900097, "White blood cell count decreased": 11.319192895109182}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/196.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/196.json
index d788eaf4cc8..9c682cdd470 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/196.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/196.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 14.19134159769352, "Acute myocardial infarction ": 9.094788349856982, "Acute pulmonary oedema ": 3.3698092643563604, "Anaemia ": 4.796132870580524, "Angina pectoris ": 5.597011332411711, "Angina unstable ": 10.93581089931697, "Aortic dissection ": 5.596485783634826, "Apnoea ": 2.88808778465734, "Atrioventricular block ": 8.102148052044232, "Atrioventricular block complete ": 20.437484510128336, "Atrioventricular block second degree ": 12.92739528985086, "Basal ganglia haemorrhage ": 17.689941080916757, "Blood loss anaemia ": 20.400359056318443, "Blood potassium increased ": 2.497932622221499, "Blood uric acid increased ": 11.002778726767062, "Bradyarrhythmia ": 7.455671547734895, "Bradycardia ": 5.438509389358259, "Brain herniation ": 11.383096145464124, "Cardiac arrest ": 3.0070814782614907, "Cardiac failure ": 2.4516980759958487, "Cardiac tamponade ": 13.20432294678302, "Cardiac ventricular thrombosis ": 4.67592896320986, "Cardiogenic shock ": 4.325679497219267, "Central sleep apnoea syndrome ": 363.1932656504565, "Cerebellar haemorrhage ": 5.5266718270642325, "Cerebral haematoma ": 28.692130836523496, "Cerebral haemorrhage ": 16.28005971916398, "Cerebral mass effect ": 22.45867772055913, "Cheyne-Stokes respiration ": 44.17474893974636, "Choking ": 2.014341742189898, "Cholestasis ": 2.148843069253679, "Conjunctival haemorrhage ": 7.081569906454659, "Contusion ": 7.249762545711899, "Coronary artery occlusion ": 4.728363378456091, "Coronary artery restenosis ": 43.64041067992903, "Coronary artery stenosis ": 15.429244526010958, "Coronary artery thrombosis ": 10.927726403589896, "Craniocerebral injury ": 6.373055062800956, "Cystitis haemorrhagic ": 4.108759857217241, "Device occlusion ": 11.192878599238936, "Diastolic dysfunction ": 5.564811636177595, "Diverticulum intestinal haemorrhagic ": 6.518462666768117, "Drug interaction ": 3.047272505639657, "Duodenal ulcer ": 7.862181802600708, "Duodenal ulcer haemorrhage ": 5.752822123621036, "Dyspnoea ": 8.702276985568632, "Dyspnoea at rest ": 57.47154940628745, "Dyspnoea exertional ": 7.623489393582469, "Dyspnoea paroxysmal nocturnal ": 31.657439989325244, "Ear haemorrhage ": 14.26053084719862, "Ecchymosis ": 29.848110851684037, "Ejection fraction decreased ": 3.424908506215968, "Electrocardiogram abnormal ": 4.66264249765424, "Eosinophilia ": 2.9476613279395525, "Epistaxis ": 20.75962277496496, "Erosive duodenitis ": 17.63518731158939, "Extravasation blood ": 44.204051593416416, "Eye haemorrhage ": 6.047507105227237, "Facial paresis ": 2.1393421651265827, "Faeces discoloured ": 3.233995014103168, "Gastric haemorrhage ": 29.407278115328136, "Gastric ulcer ": 4.592203059087188, "Gastric ulcer haemorrhage ": 10.162808738602664, "Gastritis ": 2.0756034901804195, "Gastritis erosive ": 7.441086493482119, "Gastrointestinal haemorrhage ": 12.684666894444588, "Genital haemorrhage ": 6.435570101767847, "Gingival bleeding ": 12.13186677416315, "Gout ": 11.211158014684928, "Haemarthrosis ": 2.929651493849026, "Haematemesis ": 7.436814392953587, "Haematochezia ": 2.9546280004633725, "Haematocrit decreased ": 4.875630443506753, "Haematoma ": 13.610425515700634, "Haematoma muscle ": 11.425673710578712, "Haematuria ": 16.454834224014114, "Haemoglobin decreased ": 2.987430651233945, "Haemoperitoneum ": 9.207245743825474, "Haemoptysis ": 9.466953595859737, "Haemorrhage ": 7.224607059288683, "Haemorrhage intracranial ": 19.74181988470945, "Haemorrhage subcutaneous ": 2.916010513658188, "Haemorrhage urinary tract ": 10.087832117561074, "Haemorrhagic diathesis ": 8.426369520727583, "Haemorrhagic stroke ": 18.01485207365553, "Haemorrhagic transformation stroke ": 19.48463768094077, "Haemorrhoidal haemorrhage ": 8.059538896035678, "Haemorrhoids ": 2.138532505839746, "Haemothorax ": 5.188762209688972, "Heart rate decreased ": 2.0320515213203643, "Hemiplegia ": 2.1584113307613486, "Hepatic cytolysis ": 3.1929362253178963, "Hepatitis cholestatic ": 2.300149278070388, "Hepatitis toxic ": 4.820094858388861, "Hyperlipidaemia ": 2.004781112576835, "Hyperuricaemia ": 8.397172580407103, "Hyperventilation ": 2.373989795856883, "Increased tendency to bruise ": 4.817069845158555, "Infarction ": 6.463185841828418, "International normalised ratio decreased ": 3.1884337624615133, "Intestinal haemorrhage ": 20.57750518979222, "Intracranial haematoma ": 26.691842252699665, "Intraventricular haemorrhage ": 11.893068078082251, "Iron deficiency anaemia ": 6.693318509779702, "Ischaemic cardiomyopathy ": 5.461943434486682, "Ischaemic stroke ": 3.3788468281178163, "Large intestinal haemorrhage ": 15.56491568436153, "Left ventricular dysfunction ": 2.260032367703613, "Lower gastrointestinal haemorrhage ": 9.76505367420426, "Melaena ": 20.4410477782199, "Mitral valve incompetence ": 5.302599318604846, "Mouth haemorrhage ": 2.849301697700111, "Muscle haemorrhage ": 4.548565586421685, "Myocardial infarction ": 3.3876797851558, "Myocardial ischaemia ": 2.2256297827583778, "Nocturnal dyspnoea ": 47.27474268299163, "Orthopnoea ": 8.999511539246154, "Pancreatic carcinoma metastatic ": 4.064899658670651, "Pericardial haemorrhage ": 32.62433302234234, "Petechiae ": 6.176442973481381, "Post procedural haematoma ": 12.544621739624002, "Post procedural haemorrhage ": 11.321105043922062, "Procedural haemorrhage ": 14.546583922985786, "Product residue present ": 5.024754561996318, "Product solubility abnormal ": 8.046603787996911, "Pulmonary haemorrhage ": 8.164215568312883, "Purpura ": 3.613179201347502, "Rash maculo-papular ": 4.692352370647558, "Rectal haemorrhage ": 13.95423685329321, "Retinal haemorrhage ": 3.5064055797714837, "Retroperitoneal haematoma ": 6.06720148205852, "Rhabdomyolysis ": 4.015422845178487, "Sense of oppression ": 4.6401751650130505, "Shock haemorrhagic ": 13.528784758742788, "Sinoatrial block ": 63.491637732988245, "Sinus arrest ": 35.88903264663028, "Sinus bradycardia ": 7.43863377015445, "Skin haemorrhage ": 6.427144795444262, "Sleep apnoea syndrome ": 8.144419603436068, "Spontaneous haematoma ": 17.18859803198686, "Subarachnoid haemorrhage ": 7.219619929664407, "Subcutaneous haematoma ": 13.875458546306543, "Subdural haematoma ": 18.47948232333048, "Subdural haemorrhage ": 6.94048916646107, "Suffocation feeling ": 7.012223447903515, "Supraventricular extrasystoles ": 4.25169353822942, "Therapy cessation ": 10.719597811955936, "Thrombocytopenia ": 2.0601841267370844, "Thrombosis in device ": 25.49245771222767, "Tongue haemorrhage ": 15.563762163501735, "Toxic skin eruption ": 2.7787082755835786, "Tricuspid valve incompetence ": 6.019126721289351, "Troponin increased ": 3.0822479090081094, "Upper gastrointestinal haemorrhage ": 6.997420650254858, "Urinary bladder haemorrhage ": 13.228543319656064, "Urine abnormality ": 7.024387476827147, "Vascular stent stenosis ": 82.11066654946829, "Vascular stent thrombosis ": 158.4461983929955, "Ventricular asystole ": 115.40500400675012, "Ventricular extrasystoles ": 2.075280935693549, "Wound haemorrhage ": 12.18563227308595}
\ No newline at end of file
+{"Chronic obstructive pulmonary disease": 141.20322855998197, "Pneumonia": 11.132844809588155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/197.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/197.json
index 75571d420a8..c58f3b9e670 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/197.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/197.json
@@ -1 +1 @@
-{"Muscular weakness ": 28.959563671864228, "Orthostatic hypotension ": 143.7333834452935, "Presyncope ": 62.267975873994246}
\ No newline at end of file
+{"Blood pressure decreased": 9.94446093546421, "Chest discomfort": 2.9480971432174234, "Dissociation": 461.80251896243504, "Drug ineffective": 3.895016836728786, "Drug interaction": 3.3219555573638004, "Electrocardiogram QT prolonged": 9.149609123764314, "Hypomania": 238.816437624049, "Mental disorder": 33.24999593428197, "Off label use": 5.778282400764538, "Schizophrenia": 192.80771390351524, "Suicidal ideation": 15.985482624953669, "Tardive dyskinesia": 86.4079128185948, "Weight increased": 3.382896809196199, "Withdrawal syndrome": 36.616543468221806}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/198.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/198.json
index 7b30082e8b9..e5da6fb253e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/198.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/198.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.6173348880947844, "Confusional state ": 2.592223063147274, "Drug ineffective ": 2.72054187951502, "Eye irritation ": 67.0115553044586, "Eye pain ": 12.531858574035065, "Intraocular pressure increased ": 183.10262380635325, "Ocular hyperaemia ": 30.48440017252974, "Somnolence ": 3.783756865054755, "Toxicity to various agents ": 3.4608334187773164, "Vision blurred ": 4.520321914987699}
\ No newline at end of file
+{"Cytokine release syndrome": 794.6843891100432, "Decreased appetite": 3.2002447113523065, "Haemoglobin decreased": 7.330781152975114, "Immune effector cell-associated neurotoxicity syndrome": 497.375138176136, "Malignant neoplasm progression": 11.064216574603396, "Neurotoxicity": 107.81329337021144, "Platelet count decreased": 8.313159966355384, "White blood cell count decreased": 4.661951063207062}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/199.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/199.json
index ee55609cb1b..8e5df2921ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/199.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/199.json
@@ -1 +1 @@
-{"Abdominal pain upper ": 2.032781047349109, "Abnormal dreams ": 14.619609380843826, "Abnormal weight gain ": 3.649637442603828, "Accommodation disorder ": 7.461937364148074, "Acne ": 3.3150926413451027, "Aggression ": 6.06833918123479, "Agitation ": 5.069031777480803, "Akathisia ": 5.561918901569084, "Alcohol interaction ": 6.146183776793818, "Anger ": 4.9298653301322455, "Anorgasmia ": 50.53299850638077, "Anxiety ": 4.619317314188294, "Apathy ": 4.9283939953229, "Appetite disorder ": 2.4859069152567117, "Binge eating ": 24.504277329499896, "Bipolar I disorder ": 8.610737689359066, "Blood prolactin increased ": 13.212266944216598, "Bradykinesia ": 4.544980697167464, "Bradyphrenia ": 2.543351216056098, "Bruxism ": 28.71575180135699, "Circumstance or information capable of leading to medication error ": 4.739493922506395, "Completed suicide ": 2.8416648385783367, "Constipation ": 2.6762746457250555, "Contusion ": 2.0100393669967267, "Crying ": 4.961053742186953, "Daydreaming ": 6.370097728739999, "Depersonalisation/derealisation disorder ": 12.237684036519497, "Depressed mood ": 4.078491582845115, "Depression ": 2.447345912842502, "Depressive symptom ": 6.700927110910641, "Derealisation ": 26.29518250904418, "Dissociation ": 6.12954912628522, "Disturbance in sexual arousal ": 13.768902315861965, "Dry eye ": 2.8256344247801564, "Dry mouth ": 2.2927465522187167, "Dyspepsia ": 3.215723570659224, "Ecchymosis ": 4.904730417048333, "Ejaculation delayed ": 42.90338365939984, "Ejaculation disorder ": 5.439707231671068, "Ejaculation failure ": 6.717960593777849, "Electric shock sensation ": 4.5883350338775735, "Electrocardiogram QT prolonged ": 3.0106942767589344, "Emotional poverty ": 8.21440193284497, "Energy increased ": 4.85772159000177, "Erectile dysfunction ": 5.4122021341339375, "Eructation ": 2.308912628514747, "Euphoric mood ": 2.3286922430995203, "Fear ": 3.4336967375575886, "Feeling abnormal ": 3.724847140827564, "Feeling drunk ": 3.1518764079806614, "Feeling of despair ": 6.254906620698407, "Flatulence ": 2.3325202089952977, "Food craving ": 7.71790633905546, "Formication ": 3.198366619658688, "Galactorrhoea ": 4.601627345912456, "Gastrointestinal pain ": 2.7978279130333235, "Genital hypoaesthesia ": 18.311069581603167, "Haematoma ": 2.219768101709217, "Hallucination, auditory ": 3.147963428973497, "Head discomfort ": 2.726704514541335, "Homicidal ideation ": 4.141315549519621, "Hot flush ": 2.956215049062436, "Hunger ": 11.806560583145044, "Hyperhidrosis ": 2.3676515431707954, "Hypernatraemia ": 2.136542175621704, "Hyperprolactinaemia ": 8.791477009448968, "Hypersomnia ": 2.323936572281208, "Hypomania ": 16.014805547764624, "Hyponatraemia ": 3.923799953694836, "Impulsive behaviour ": 6.137068463420575, "Inappropriate antidiuretic hormone secretion ": 3.569476725042221, "Increased appetite ": 10.064717422334356, "Increased tendency to bruise ": 3.0410156606306, "Indifference ": 14.373453475273353, "Initial insomnia ": 8.705332722646437, "Insomnia ": 3.288150674753925, "Intentional overdose ": 2.5467565856706247, "Intentional self-injury ": 5.136491299394668, "Intestinal haemorrhage ": 2.372153769988862, "Intraocular pressure increased ": 2.179795843710559, "Irritability ": 5.672481692463814, "Libido decreased ": 23.455325710609827, "Libido increased ": 7.98195071012703, "Logorrhoea ": 6.135639487946842, "Loss of libido ": 10.329641100706752, "Major depression ": 5.2675713168562375, "Mania ": 9.3049790640852, "Mental fatigue ": 4.009657135944759, "Middle insomnia ": 3.369377829495865, "Mood altered ": 3.729614605955202, "Mood swings ": 2.4931073899653287, "Motion sickness ": 6.370097728739999, "Muscle tightness ": 2.632166779774327, "Muscle twitching ": 2.1542976905779208, "Mydriasis ": 3.3979059289520803, "Nausea ": 3.9446164944480167, "Negative thoughts ": 25.698832995465622, "Nervousness ": 4.313540760896908, "Night sweats ": 6.325316967404075, "Nightmare ": 9.05262022820338, "Obsessive thoughts ": 9.956686754305707, "Orgasm abnormal ": 43.18643723930584, "Overdose ": 2.0170525421968275, "Panic attack ": 3.93591986177056, "Panic disorder ": 2.914758262985242, "Panic reaction ": 3.175111381907692, "Persecutory delusion ": 3.43739688411783, "Photopsia ": 2.167606164064148, "Poisoning deliberate ": 3.4187120160276314, "Poor quality sleep ": 3.938763264138833, "Pregnancy ": 8.009044031771037, "Prescribed overdose ": 4.434573670795789, "Prescribed underdose ": 2.0943634386167918, "Product administered to patient of inappropriate age ": 4.60572362910094, "Product use in unapproved indication ": 4.536541257657147, "Pruritus ": 5.376291387266709, "Psychomotor hyperactivity ": 6.781936190857386, "Reaction to excipient ": 20.763838468148062, "Restless legs syndrome ": 7.291873065479611, "Restlessness ": 4.904336087628148, "Retching ": 2.37121056785923, "Salivary hypersecretion ": 5.358264333240608, "Sedation ": 2.79464008523786, "Self-destructive behaviour ": 7.692208537290067, "Self-injurious ideation ": 18.78436985313768, "Serotonin syndrome ": 17.840530724195492, "Sexual dysfunction ": 28.57218725136006, "Sleep disorder ": 3.030216949939113, "Sluggishness ": 2.2588160581806127, "Social avoidant behaviour ": 4.335618633864014, "Somnambulism ": 3.994705355378289, "Somnolence ": 2.576071450070599, "Sopor ": 2.399595913671608, "Subcutaneous haematoma ": 5.788091291239834, "Suicidal behaviour ": 5.196808085591319, "Suicidal ideation ": 13.18737448286065, "Suicide attempt ": 4.42011278737771, "Tachyphrenia ": 18.05471574742947, "Tearfulness ": 2.658795535421364, "Tension ": 10.457214105381734, "Tension headache ": 2.898969126518746, "Therapeutic response unexpected ": 3.3631327178134267, "Therapy cessation ": 18.17366649136578, "Therapy change ": 6.554115589375809, "Thinking abnormal ": 4.233179924806692, "Tic ": 7.744349881724241, "Tinnitus ": 2.011666935494608, "Treatment noncompliance ": 2.8999430864864286, "Tremor ": 2.187746837964087, "Trismus ": 2.0073746606918803, "Underdose ": 4.336780606208564, "Urinary retention ": 2.5784244379528025, "Vertigo ": 2.9199352668768874, "Vomiting ": 2.7074595658670733, "Weight increased ": 4.703587653345733, "Withdrawal syndrome ": 3.2685492571098336, "Wrong patient ": 27.577075817966666, "Wrong technique in product usage process ": 5.63108858441618}
\ No newline at end of file
+{"Acute generalised exanthematous pustulosis": 3.698680034606853, "Acute pulmonary oedema": 18.011893315534063, "Acute respiratory failure": 3.050363444622387, "Adverse event": 4.028966180498797, "Airway complication of anaesthesia": 177.18371626482366, "Airway peak pressure increased": 229.77927191725504, "Anaesthetic complication": 31.643062098232445, "Anaphylactic reaction": 48.94939742335712, "Anaphylactic shock": 62.6190984551573, "Anaphylactoid reaction": 44.795015537124655, "Anaphylactoid shock": 36.33737764168267, "Angioedema": 2.5660743754284328, "Apnoea": 10.29115473572987, "Arteriospasm coronary": 41.87458609189188, "Aspiration": 5.075066438870195, "Atrioventricular block": 3.5515985677646245, "Atrioventricular block complete": 19.163277842780023, "Atrioventricular block second degree": 16.313899374012287, "Blood pressure decreased": 21.07040197758886, "Blood pressure systolic decreased": 6.361915992810059, "Bradycardia": 38.4081417612463, "Bronchospasm": 55.95619925019741, "Cardiac arrest": 23.451546517633684, "Cardio-respiratory arrest": 6.100238223142041, "Cholestatic liver injury": 24.5362067467291, "Circulatory collapse": 4.780937359662325, "Cyanosis": 4.183342742220885, "Deafness neurosensory": 7.269229752610314, "Delayed recovery from anaesthesia": 37.4221123560941, "Depressed level of consciousness": 3.6274034938492976, "Disseminated intravascular coagulation": 2.062691717823951, "Drug hypersensitivity": 3.6592565639010193, "Drug reaction with eosinophilia and systemic symptoms": 2.77366468988606, "Electrocardiogram ST segment depression": 22.264203309918507, "Electrocardiogram ST segment elevation": 13.921814803832056, "Endotracheal intubation": 45.7840241160085, "Endotracheal intubation complication": 122.413417303142, "Erythema": 5.041655642873737, "Extra dose administered": 7.006976829676188, "Eyelid oedema": 13.404843000973436, "Face oedema": 2.4530694055438267, "Flushing": 3.529586010827188, "Haemodynamic instability": 7.327077201472442, "Heart rate decreased": 4.839388247126134, "Hypersensitivity": 3.0808080346988667, "Hypertensive crisis": 5.792686233237613, "Hypotension": 7.281212135856032, "Hypothermia": 5.165073722305402, "Hypotonia": 2.632249551540651, "Hypoventilation": 65.09472879591365, "Hypoxia": 11.7304719230179, "Hypoxic-ischaemic encephalopathy": 19.796226954076065, "Incorrect dose administered": 4.5759266561682015, "Intensive care": 20.362214274538324, "Kounis syndrome": 197.36269659019072, "Laryngeal oedema": 6.82857273152593, "Laryngospasm": 87.22771154490684, "Lip oedema": 3.617056330707393, "Maternal exposure during delivery": 11.925797637085072, "Mechanical ventilation": 22.862618559067197, "Movement disorder": 2.1267923279316525, "Muscle rigidity": 7.333131929815521, "Muscle twitching": 2.3655911656987265, "Negative pressure pulmonary oedema": 354.74815181638536, "Neuromuscular block prolonged": 287.7340574132472, "Normochromic normocytic anaemia": 18.674378491525665, "Obstructive airways disorder": 4.784842904081813, "Oxygen saturation decreased": 15.03968629781783, "Papule": 2.642221573526292, "Paralysis": 5.2147743473316295, "Pharyngeal oedema": 6.426404059869157, "Pneumothorax": 4.495733503763975, "Post procedural haemorrhage": 8.739605800234902, "Prinzmetal angina": 51.024201046635234, "Procedural nausea": 60.397401222571, "Procedural vomiting": 94.78763841099264, "Product administered to patient of inappropriate age": 15.295254625854325, "Product quality issue": 2.442112222627777, "Product storage error": 2.182168616126876, "Product use issue": 2.3194109977212274, "Pulmonary oedema": 8.726714111525514, "Pulseless electrical activity": 52.308664320776586, "Recurrence of neuromuscular blockade": 7063.147091676085, "Respiratory arrest": 19.376069631782933, "Respiratory depression": 6.5374224362745945, "Respiratory disorder": 2.1228158710547325, "Respiratory failure": 3.796122242826221, "Resuscitation": 17.91107453233407, "Shock": 5.305633272916933, "Sinus arrest": 12.182242646250144, "Sinus tachycardia": 3.4075240480461804, "Supraventricular tachycardia": 12.379022920905095, "Swelling of eyelid": 3.497896514802358, "Tachycardia": 3.103415734397047, "Therapeutic product effect delayed": 17.856635715926203, "Therapeutic product effect incomplete": 2.119096417483677, "Tongue oedema": 3.003541560232772, "Type I hypersensitivity": 29.984702520448167, "Underdose": 7.156178516388191, "Upper airway obstruction": 32.19801513753912, "Urticaria": 3.899561093333368, "Ventricular extrasystoles": 3.838730214245019, "Ventricular fibrillation": 16.162603349849242, "Ventricular tachycardia": 7.083296624189004, "Wheezing": 3.9781564798951767, "Wrong product administered": 2.595042666644182}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/2.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/2.json
index 0e700f7bb25..76370f290db 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/2.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/2.json
@@ -1 +1 @@
-{"Abdominal lymphadenopathy ": 13.045411982848195, "Abdominal mass ": 4.55206955826119, "Acute abdomen ": 4.209149135288143, "Adjustment disorder with depressed mood ": 4.237392635996414, "Asthma ": 11.18705619156061, "Atypical mycobacterial infection ": 6.40049620029478, "Autoimmune disorder ": 2.074002188302761, "Back pain ": 4.389003158639491, "Blood HIV RNA increased ": 25.67870412641772, "Blood bicarbonate decreased ": 2.735628081751657, "Blood cholesterol increased ": 2.265947060175652, "Blood lactic acid increased ": 5.990125632948553, "Blood triglycerides increased ": 4.88779787963303, "Bone erosion ": 4.959304350083734, "Breast abscess ": 8.032117069749779, "Breast cancer stage II ": 9.520238510807271, "Bursitis ": 47.20459823749535, "CD4 lymphocytes abnormal ": 25.96849687412544, "CD4 lymphocytes decreased ": 16.693340216124966, "CSF HIV escape syndrome ": 21.08616618887081, "Cachexia ": 5.432932494579837, "Cardiothoracic ratio increased ": 92.33324993520672, "Cerebral toxoplasmosis ": 15.375319019851752, "Chorea ": 3.7998022292620703, "Coeliac disease ": 79.09586377480385, "Constipation ": 6.056210504784032, "Contraindicated product administered ": 12.615542890687712, "Contrast media allergy ": 16.890621327361735, "Cryptosporidiosis infection ": 40.31127095948433, "Cytomegalovirus chorioretinitis ": 8.867005244954214, "Cytomegalovirus oesophagitis ": 27.96341927510422, "Decreased immune responsiveness ": 21.23767603914714, "Depressive symptom ": 2.340914897702409, "Diplopia ": 5.919992515891461, "Disseminated mycobacterium avium complex infection ": 69.60096594591275, "Drug hypersensitivity ": 8.931655246947033, "Drug intolerance ": 9.14315800120726, "Drug level below therapeutic ": 2.100719136037982, "Drug resistance ": 8.986599769085734, "Dysdiadochokinesis ": 17.0516850194585, "Dyslipidaemia ": 10.37914977592417, "Erythema ": 3.145635412384758, "Exposure during pregnancy ": 21.520575829574344, "Eyelid ptosis ": 22.46328883559437, "Facial wasting ": 31.997446216782944, "Fanconi syndrome ": 4.361520189598277, "Fat redistribution ": 54.17487555254509, "Fat tissue increased ": 12.454398859117411, "Fluid retention ": 33.842645036699935, "Foetal death ": 125.86364401362368, "Food allergy ": 240.7774194936877, "Genotype drug resistance test positive ": 4.022235736866002, "Glucose tolerance impaired ": 5.069443730099772, "Glycosuria ": 3.383961996854826, "HIV infection ": 12.6857707366339, "HIV-associated neurocognitive disorder ": 40.65245686934084, "Hepatic cirrhosis ": 2.746889785944175, "Hepatic enzyme increased ": 16.164598524776167, "Hepatic necrosis ": 2.747350681839932, "Hepatosplenomegaly ": 4.62450283413216, "High density lipoprotein decreased ": 4.3398256019239785, "Hyperbilirubinaemia ": 2.189000727463703, "Hypercholesterolaemia ": 2.5043014690160077, "Hyperhidrosis ": 6.291607386652432, "Hyperlactacidaemia ": 6.503108083219105, "Hyperphagia ": 3.801172835424252, "Hypersensitivity ": 6.378976133651239, "Hypertension ": 5.58638880782433, "Hypertriglyceridaemia ": 5.814932666104827, "Hypophosphataemia ": 3.717831182234173, "Ileal ulcer ": 9.03149706490749, "Immune reconstitution inflammatory syndrome ": 17.352714529019355, "Immunodeficiency ": 161.58609277409082, "Impetigo ": 8.16939694290088, "Infection ": 8.592568638456447, "Infusion related reaction ": 24.46678274043601, "Intentional product misuse ": 15.989563109724989, "Intra-abdominal haematoma ": 4.193291201577518, "Joint swelling ": 12.71982779552135, "Kaposi's sarcoma ": 9.935784191756234, "Lactic acidosis ": 2.256909516030749, "Lip discolouration ": 8.50009195042409, "Lip erosion ": 8.871796013938816, "Lipids abnormal ": 10.272007388770064, "Lipoatrophy ": 46.42425179826252, "Lipodystrophy acquired ": 65.03054498160915, "Lipoedema ": 18.16045255675414, "Live birth ": 2.278848749431539, "Low density lipoprotein increased ": 6.529795958369237, "Lymphoedema ": 2.0673110052091954, "Magnetic resonance imaging head abnormal ": 3.2284729614290035, "Maternal exposure before pregnancy ": 6.627569793842597, "Maternal exposure during pregnancy ": 3.212953764124815, "Meningitis viral ": 7.782808416034403, "Metastatic malignant melanoma ": 2.146734443215766, "Mitochondrial cytopathy ": 15.408894107948033, "Mitochondrial myopathy ": 154.91757398474897, "Mitochondrial toxicity ": 169.22159041294174, "Multiple-drug resistance ": 9.396463745113849, "Muscle haemorrhage ": 3.1421042455548305, "Mycobacterium avium complex infection ": 4.033079831110975, "Mycobacterium test positive ": 28.265747711225867, "Nail discolouration ": 3.662884932648735, "Nephropathy toxic ": 2.357228084229724, "Neurological symptom ": 2.1239278787773963, "Obliterative bronchiolitis ": 13.102626038528143, "Oesophageal candidiasis ": 9.745763986665612, "Off label use ": 2.4683448679906657, "Ophthalmoplegia ": 5.394833940515004, "Oral candidiasis ": 2.075965350732973, "Osteochondrosis ": 7.523871228005273, "Overdose ": 8.134701076405351, "Pain ": 2.175452404913429, "Pathogen resistance ": 30.04171271939711, "Pelvic inflammatory disease ": 12.334426810172763, "Pneumocystis jirovecii infection ": 7.609767410855049, "Polymerase chain reaction ": 44.75061526696715, "Portal hypertension ": 4.956103283268751, "Premature labour ": 2.6015549874251267, "Prescribed overdose ": 53.5035246367101, "Product use issue ": 11.108501861523091, "Progressive external ophthalmoplegia ": 1506.060606607389, "Progressive multifocal leukoencephalopathy ": 4.986634574696754, "Psoriasis ": 22.82069497717423, "Pulmonary tuberculosis ": 4.683215957035845, "Rash ": 2.771475918095327, "Rash erythematous ": 24.002935111778584, "Renal function test abnormal ": 2.818740823808979, "Renal hypoplasia ": 24.746920393446317, "Renal tubular dysfunction ": 4.546955439109031, "Rheumatoid arthritis ": 13.68568399991304, "Sleep terror ": 2.150067382438213, "Superinfection bacterial ": 23.86035221745633, "Susac's syndrome ": 65.91390191458981, "Temperature regulation disorder ": 188.0771604736076, "Thrombocytopenia ": 7.725832481719602, "Toxoplasmosis ": 6.091908032087636, "Treatment failure ": 15.659686250359382, "Treatment noncompliance ": 5.69494683181208, "Upper respiratory tract infection ": 68.09805521754512, "Urine abnormality ": 2.0456032338440244, "Varicocele ": 16.96637215021089, "Viraemia ": 8.725279691354764, "Viral load increased ": 4.006606114955514, "Viral mutation identified ": 77.8069111877787, "Virologic failure ": 50.577737318825946}
\ No newline at end of file
+{"Cerebrospinal fluid leakage": 4400.767758996852, "Seizure": 27.042744305446504}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/20.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/20.json
index 4d13fd0988e..a8e6b5aec0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/20.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/20.json
@@ -1 +1 @@
-{"Activated partial thromboplastin time prolonged ": 9.794300711062869, "Analgesic therapy ": 41.7137727036254, "Antacid therapy ": 70.54966664321147, "Anticoagulant therapy ": 42.79248108704672, "Aortic stenosis ": 15.788116947577956, "Appendicitis ": 5.725439129869816, "Appendicolith ": 18.89066446471517, "Aspiration ": 6.722209175374538, "Asthma ": 16.034088047566755, "Asthma-chronic obstructive pulmonary disease overlap syndrome ": 1026.0800915136883, "Ataxia ": 17.626057577583772, "Atrial fibrillation ": 3.682160639153183, "Bacterial infection ": 4.561052833094216, "Benign prostatic hyperplasia ": 11.92723072463793, "Blood bilirubin increased ": 13.905472518328969, "Blood calcium increased ": 9.75717599082466, "Blood test abnormal ": 13.871090054510477, "Breast conserving surgery ": 133.00163975369662, "Breath sounds abnormal ": 69.76869441116006, "Bronchial obstruction ": 209.5070872558104, "Bronchial wall thickening ": 160.32214726127918, "Bronchiectasis ": 141.1567129153049, "Bronchiolitis ": 16.184627751824355, "Bronchopulmonary aspergillosis allergic ": 72.1848462799333, "Cardiac murmur ": 60.81870293394235, "Cardiogenic shock ": 3.63159670714588, "Carotid arteriosclerosis ": 69.48812564852915, "Cataract ": 10.95899860812604, "Cellulitis ": 3.005973076695175, "Cholelithiasis ": 24.42525250159686, "Chronic obstructive pulmonary disease ": 29.154484678147117, "Chronic sinusitis ": 20.93627173504365, "Condition aggravated ": 4.230613060217498, "Coronary artery bypass ": 51.48872669795927, "Cough ": 2.084997427364024, "Crepitations ": 15.79355590154366, "Crohn's disease ": 2.3477185887780525, "Dermatitis atopic ": 92.34949312126048, "Dupuytren's contracture ": 82.26474012607873, "Dupuytren's contracture operation ": 4289.238193960354, "Dyspepsia ": 5.982304367531809, "Dysphagia ": 5.144541199056696, "Dyspnoea ": 2.214707649877924, "Dyspnoea exertional ": 11.156041974721877, "Emphysema ": 35.37101046229918, "Eosinophil count increased ": 11.046773925916243, "Full blood count abnormal ": 13.226810655026258, "Fungal disease carrier ": 3630.822227419112, "Gastroenteritis ": 31.08316455881353, "Gastrooesophageal reflux disease ": 10.287800028280795, "Granuloma ": 23.244855531122948, "Graves' disease ": 12.300312738030945, "Haemoptysis ": 2.286225686888364, "Hepatic enzyme increased ": 6.53294544579161, "Hepatotoxicity ": 21.478130648738183, "Hypercapnia ": 87.65943224161082, "Hypertension ": 2.0391543636049145, "Hypomania ": 115.1590019708789, "Hypothyroidism ": 2.0899723832883224, "Ill-defined disorder ": 3.8833784063394505, "Impaired quality of life ": 11.92162497011097, "Inguinal hernia repair ": 924.4685547655546, "Jaundice cholestatic ": 100.8431385813956, "Loss of personal independence in daily activities ": 9.263379861637183, "Lower respiratory tract infection ": 5.4037397425142055, "Lung diffusion disorder ": 1409.8429305547263, "Lung diffusion test decreased ": 155.189601036973, "Lung disorder ": 7.157501990190728, "Lung neoplasm ": 206.0748539316517, "Lung neoplasm malignant ": 21.55655238078973, "Meniere's disease ": 34.264617464400864, "Mycobacterium test positive ": 272.05132804874165, "Nasal congestion ": 7.64959702258826, "Nasal polyps ": 140.08611178974064, "Nephrectomy ": 38.63190251255492, "No adverse event ": 2.033384056312953, "Nocturnal dyspnoea ": 102.4710127386318, "Obstruction ": 37.10626431864435, "Obstructive airways disorder ": 38.78514261709207, "Oedema peripheral ": 5.260170690109287, "Oral candidiasis ": 5.240636219464246, "Oropharyngeal candidiasis ": 342.6936893694759, "Oropharyngeal discomfort ": 22.966397516323312, "Osteonecrosis of jaw ": 17.730997735917917, "Pneumonia ": 4.887498549939374, "Productive cough ": 12.673877489259858, "Psychotic disorder ": 17.783332048865734, "Pulmonary mass ": 9.542625971180897, "Renal cyst ": 9.99700219557947, "Respiratory disorder ": 13.193316309498613, "Respiratory symptom ": 41.88759750196953, "Rhinitis allergic ": 73.9618636737396, "Sarcoidosis ": 92.18287781947332, "Schizophrenia ": 68.72433453293026, "Sinus disorder ": 20.17617332845585, "Sinus pain ": 15.256119622958796, "Sinusitis ": 2.639619963303937, "Sleep disorder due to a general medical condition ": 42.458103823346725, "Sputum discoloured ": 25.707633823946264, "Sputum purulent ": 167.39246541651318, "Stenotrophomonas infection ": 263.0032296998307, "Symptom recurrence ": 75.6748400105427, "Therapeutic product effect incomplete ": 11.954819182696554, "Therapy cessation ": 43.81347348211298, "Therapy interrupted ": 34.8688141095107, "Total lung capacity increased ": 1487.0384993080331, "Type 2 diabetes mellitus ": 19.028015269109563, "Upper respiratory tract infection ": 5.824487494924433, "Upper-airway cough syndrome ": 17.52272997128199, "Ventricular hypokinesia ": 94.36227366591687, "Vital capacity decreased ": 92.33591239843228, "Weight increased ": 4.775470346259801, "Wheezing ": 29.2749140088134}
\ No newline at end of file
+{"Acute kidney injury": 2.92553289480419, "Alanine aminotransferase abnormal": 94.10219370372036, "Arthritis": 8.015668489391434, "Atrial fibrillation": 3.90011958111815, "Blood pressure abnormal": 16.221155519769955, "Blood pressure diastolic abnormal": 126.10292480836006, "Blood pressure diastolic decreased": 42.824865341921225, "Blood pressure fluctuation": 10.003419313012758, "Blood pressure systolic abnormal": 128.3011620091081, "Blood pressure systolic increased": 12.809967703396197, "Bone density abnormal": 26.54421966391294, "Bone pain": 5.057622175263924, "Bronchitis": 6.872073568617372, "C-reactive protein increased": 4.508806645776192, "Carpal tunnel syndrome": 30.76741645086172, "Cystocele": 208.705853387233, "Disease recurrence": 10.52068280893208, "Drug interaction": 2.6725078114305005, "Drug withdrawal syndrome": 5.578997902856047, "Feeling cold": 3.069383043430526, "Fibromyalgia": 11.566126105421327, "Gait disturbance": 2.7199392187332534, "General physical health deterioration": 3.7396188839798192, "Heart rate decreased": 7.617924085514173, "Hepatic enzyme increased": 2.8789150738840488, "Hepatitis": 5.182508495608797, "Hypersensitivity": 2.3373591013416632, "Hypokinesia": 11.31175437897931, "Inflammation": 3.3919642194432917, "Infusion related reaction": 3.4797199909375998, "Injection site bruising": 13.30794375957594, "Injection site haemorrhage": 14.555397313196542, "Joint swelling": 2.5442527299246827, "Limb injury": 12.253353225594433, "Limb mass": 62.08834775715734, "Liver function test abnormal": 12.716323075861728, "Musculoskeletal pain": 5.539037358927272, "Neuropathy peripheral": 3.266985132990228, "Oral herpes": 11.519342555804696, "Osteitis": 83.46835268608572, "Osteoarthritis": 8.714316233681705, "Osteomyelitis": 17.399752673986765, "Osteonecrosis of jaw": 48.64531299490949, "Osteopenia": 6.537883717501369, "Osteoporosis": 3.124835017382656, "Pain": 2.3953442279973878, "Pericarditis": 3.342855518431429, "Pleural effusion": 4.006400009328172, "Poor venous access": 191.3726483021597, "Procedural pain": 28.83017076200957, "Rectal prolapse": 225.0546184347296, "Red blood cell sedimentation rate abnormal": 62.00997749526741, "Rheumatoid arthritis": 6.655821182683525, "Sinus tachycardia": 11.970369250518496, "Sleep disorder": 2.056634791318324, "Spinal stenosis": 27.86975414761918, "Stress": 6.108713715741348, "Thermal burn": 42.750243205747225, "Vitamin D decreased": 53.85487049570725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/200.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/200.json
index 70f06efc207..ea42c96df94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/200.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/200.json
@@ -1 +1 @@
-{"Intraocular pressure increased ": 184.02015038649944}
\ No newline at end of file
+{"Acute coronary syndrome": 14.18123879751911, "Acute myocardial infarction": 9.088312908134576, "Acute pulmonary oedema": 3.3674107020081565, "Anaemia": 4.792716615826325, "Angina pectoris": 5.593026399990932, "Angina unstable": 10.928026299029318, "Aortic dissection": 5.59250241324721, "Apnoea": 2.8860320403588813, "Atrioventricular block": 8.096380482297263, "Atrioventricular block complete": 20.422934275514184, "Atrioventricular block second degree": 12.918193368778365, "Basal ganglia haemorrhage": 17.677350055938565, "Blood loss anaemia": 20.385836006284023, "Blood potassium increased": 2.496154590736095, "Blood uric acid increased": 10.9949462055992, "Bradyarrhythmia": 7.450364845721653, "Bradycardia": 5.434465590170487, "Brain herniation": 11.374993809387217, "Cardiac arrest": 3.004940514156303, "Cardiac failure": 2.4497284582870416, "Cardiac tamponade": 13.194923829483663, "Cardiac ventricular thrombosis": 4.672600769486689, "Cardiogenic shock": 4.322600281455882, "Central sleep apnoea syndrome": 362.93471584802313, "Cerebellar haemorrhage": 5.522738122794619, "Cerebral haematoma": 28.671704250141968, "Cerebral haemorrhage": 16.268464590339512, "Cerebral mass effect": 22.442692398907173, "Cheyne-Stokes respiration": 44.143306746537945, "Choking": 2.012907951685276, "Cholestasis": 2.1473134628560486, "Conjunctival haemorrhage": 7.0765290902506335, "Contusion": 7.244599654340114, "Coronary artery occlusion": 4.724997638308323, "Coronary artery restenosis": 43.60934881001079, "Coronary artery stenosis": 15.41826149953554, "Coronary artery thrombosis": 10.919948193184444, "Craniocerebral injury": 6.368518903716274, "Cystitis haemorrhagic": 4.105835341271633, "Device occlusion": 11.184911299990402, "Diastolic dysfunction": 5.560850785256481, "Diverticulum intestinal haemorrhagic": 6.5138230680150695, "Drug interaction": 3.045102432227071, "Duodenal ulcer": 7.85658530861452, "Duodenal ulcer haemorrhage": 5.748727404698567, "Dyspnoea": 8.695940887389222, "Dyspnoea at rest": 57.43063281680008, "Dyspnoea exertional": 7.618061447573855, "Dyspnoea paroxysmal nocturnal": 31.63490670143746, "Ear haemorrhage": 14.25038039508051, "Ecchymosis": 29.826857783822657, "Ejection fraction decreased": 3.4224705899003265, "Electrocardiogram abnormal": 4.659323552313481, "Eosinophilia": 2.945562999894669, "Epistaxis": 20.7448313995927, "Erosive duodenitis": 17.514215555376964, "Extravasation blood": 44.172588191445485, "Eye haemorrhage": 6.0432021037232495, "Facial paresis": 2.137819432729089, "Faeces discoloured": 3.231692949457732, "Gastric haemorrhage": 29.38634058723716, "Gastric ulcer": 4.5858711919559525, "Gastric ulcer haemorrhage": 10.155574444960424, "Gastritis": 2.0741260471710405, "Gastritis erosive": 7.42770038110147, "Gastrointestinal haemorrhage": 12.675631881798934, "Genital haemorrhage": 6.430989446292358, "Gingival bleeding": 12.123229652373457, "Gout": 11.203176638513517, "Haemarthrosis": 2.9275662156135045, "Haematemesis": 7.43085591863739, "Haematochezia": 2.9522318206756446, "Haematocrit decreased": 4.87215966867938, "Haematoma": 13.600732517554258, "Haematoma muscle": 11.417540489429, "Haematuria": 16.443115439202668, "Haemoglobin decreased": 2.985303612911687, "Haemoperitoneum": 9.200692216419434, "Haemoptysis": 9.460213237844595, "Haemorrhage": 7.219462017314948, "Haemorrhage intracranial": 19.727763449709418, "Haemorrhage subcutaneous": 2.913934923595036, "Haemorrhage urinary tract": 10.080651626796415, "Haemorrhagic diathesis": 8.42037157187717, "Haemorrhagic stroke": 18.002026949195187, "Haemorrhagic transformation stroke": 19.47076909181008, "Haemorrhoidal haemorrhage": 8.053802164459556, "Haemorrhoids": 2.137010282112985, "Haemothorax": 5.185069041603913, "Heart rate decreased": 2.030605061579656, "Hemiplegia": 2.156875008570613, "Hepatic cytolysis": 3.190663241071686, "Hepatitis cholestatic": 2.2985120606209115, "Hepatitis toxic": 4.816664012575751, "Hyperlipidaemia": 2.0033541418574217, "Hyperuricaemia": 8.391195363188555, "Hyperventilation": 2.372300037540408, "Increased tendency to bruise": 4.813641116255154, "Infarction": 6.458585299641441, "International normalised ratio decreased": 3.186164338969029, "Intestinal haemorrhage": 21.03161312581302, "Intracranial haematoma": 26.67284348880717, "Intraventricular haemorrhage": 11.884602708807543, "Iron deficiency anaemia": 6.686167001461, "Ischaemic cardiomyopathy": 5.458055755808496, "Ischaemic stroke": 3.376441618894775, "Large intestinal haemorrhage": 15.55383679062142, "Left ventricular dysfunction": 2.258423760132573, "Lower gastrointestinal haemorrhage": 9.758102592820276, "Melaena": 20.42380411221432, "Mitral valve incompetence": 5.298824811563168, "Mouth haemorrhage": 2.847273622023609, "Muscle haemorrhage": 4.545328065823463, "Myocardial infarction": 3.3852674544520545, "Myocardial ischaemia": 2.2240456155765203, "Nocturnal dyspnoea": 47.24109093664536, "Orthopnoea": 8.993105681500293, "Pancreatic carcinoma metastatic": 4.062006378083061, "Pericardial haemorrhage": 32.558357402857006, "Petechiae": 6.172045875074043, "Post procedural haematoma": 12.535692895271476, "Post procedural haemorrhage": 11.313045991047142, "Procedural haemorrhage": 14.536229663335472, "Product residue present": 5.0211779703557085, "Product solubility abnormal": 8.040876516338562, "Pulmonary haemorrhage": 8.158403992756023, "Purpura": 3.610607202377466, "Rash maculo-papular": 4.689011455180608, "Rectal haemorrhage": 13.944299533675526, "Retinal haemorrhage": 3.503909727910103, "Retroperitoneal haematoma": 6.062882995713654, "Rhabdomyolysis": 4.0125640447204844, "Sense of oppression": 4.636872439740137, "Shock haemorrhagic": 13.519153581252205, "Sinoatrial block": 63.446442521043714, "Sinus arrest": 35.86348459300934, "Sinus bradycardia": 7.43333852702189, "Skin haemorrhage": 6.420368802818183, "Sleep apnoea syndrome": 8.134990669995823, "Spontaneous haematoma": 17.176362782619623, "Subarachnoid haemorrhage": 7.2144805444788975, "Subcutaneous haematoma": 13.86558182104534, "Subdural haematoma": 18.466324639495884, "Subdural haemorrhage": 6.935549041714955, "Suffocation feeling": 7.007232212910333, "Supraventricular extrasystoles": 4.248667303108736, "Therapy cessation": 10.711967147722389, "Thrombocytopenia": 2.0585231448411863, "Thrombosis in device": 25.474311601385647, "Tongue haemorrhage": 15.552684468927318, "Toxic skin eruption": 2.7767303369435226, "Tricuspid valve incompetence": 6.014842321400651, "Troponin increased": 3.080053992708326, "Upper gastrointestinal haemorrhage": 6.990528346089608, "Urinary bladder haemorrhage": 13.21912737377838, "Urine abnormality": 7.0193877182608775, "Vascular stent stenosis": 82.05221464244934, "Vascular stent thrombosis": 158.33336032632988, "Ventricular asystole": 115.3228604639432, "Ventricular extrasystoles": 2.073803776672144, "Wound haemorrhage": 12.17695853632586}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/201.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/201.json
index ab43187e4cf..fc4b0a1db1f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/201.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/201.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 16.6327666826383, "Adverse drug reaction ": 7.406526535955066, "Affective disorder ": 15.975556950926018, "Aggression ": 13.718824718970282, "Anger ": 8.412027317854058, "Anticonvulsant drug level increased ": 53.10643467084547, "Behaviour disorder ": 31.83180048056962, "Coagulopathy ": 11.621960265885397, "Cognitive disorder ": 11.773118964915284, "Delirium ": 2.9891997513517103, "Depressed mood ": 5.250185683210288, "Depression ": 3.860691487296666, "Drug ineffective ": 3.706601759352004, "Drug ineffective for unapproved indication ": 19.57758478632129, "Drug intolerance ": 3.0202577624951927, "Drug resistance ": 9.846605225472588, "Dysarthria ": 3.353894036007678, "Dystonia ": 7.855907506312775, "Epilepsy ": 11.911218636710496, "Exposure during pregnancy ": 3.41206712951712, "Foetal exposure during pregnancy ": 2.727986055011248, "Gait disturbance ": 2.176449379460503, "Generalised tonic-clonic seizure ": 8.376903608315061, "Gingival disorder ": 47.87628306976799, "Hallucination ": 4.337772292008388, "Hallucination, visual ": 4.354156378080129, "Hyponatraemia ": 3.1231792000907967, "Intestinal atresia ": 1301.3554673539454, "Irritability ": 9.979120438565484, "Maternal exposure before pregnancy ": 55.54997841708654, "Maternal exposure during breast feeding ": 31.63918674749975, "Maternal exposure during pregnancy ": 13.402411002774071, "Memory impairment ": 6.0700529536339065, "Mood swings ": 8.259207953150085, "Multiple-drug resistance ": 383.9333592629885, "Myoclonic epilepsy ": 80.28682712562556, "Myoclonus ": 12.946037358036394, "Nephrolithiasis ": 2.760119299145742, "Off label use ": 7.778001872383929, "Overdose ": 9.244613032529807, "Oxygen saturation decreased ": 2.0226916491779696, "Partial seizures ": 13.619399023248173, "Partial seizures with secondary generalisation ": 610.7360466308605, "Patent ductus arteriosus ": 53.23991995776781, "Petit mal epilepsy ": 23.244622915869808, "Postictal paralysis ": 345.63629709145465, "Premature baby ": 11.030295800604376, "Premature delivery ": 24.3147215911612, "Prescribed overdose ": 4.52465246155034, "Product use in unapproved indication ": 2.515080837778473, "Product use issue ": 3.796214371767524, "Psychotic disorder ": 3.146909279314742, "Pulmonary haemorrhage ": 17.43455959639538, "Respiratory arrest ": 3.03289447280678, "Salivary hypersecretion ": 9.206596484649689, "Seizure ": 16.780753532714236, "Somnolence ": 3.6738898939732985, "Speech disorder ": 2.9433795418342923, "Status epilepticus ": 79.90432061527258, "Suicidal ideation ": 5.3183167014938695, "Therapeutic product effect incomplete ": 2.8306722230930075, "Therapeutic product ineffective for unapproved indication ": 625.9010999964784, "Therapeutic response unexpected ": 12.308380398785625, "Therapy non-responder ": 3.3030826995273275, "Treatment failure ": 2.2359148514497305, "Underdose ": 5.9146100755234645, "Weight increased ": 4.52689709748678}
\ No newline at end of file
+{"Muscular weakness": 28.959563671864228, "Orthostatic hypotension": 143.70243588949037, "Presyncope": 62.267975873994246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/202.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/202.json
index 5b479929fd8..9b0af28240c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/202.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/202.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 4.2286544214840704, "Adverse drug reaction ": 7.657926244819743, "Adverse event ": 4.620994882885323, "Affective disorder ": 48.848659447160486, "Aggression ": 21.39616270142542, "Agitation ": 3.67304783014517, "Anger ": 14.593799580341882, "Anxiety ": 2.6102226933160275, "Apathy ": 4.902148692531389, "Aphasia ": 2.0319974394952047, "Ataxia ": 2.857977774886954, "Atonic seizures ": 65.32405116475624, "Aura ": 86.71754002694297, "Balance disorder ": 3.756276233966533, "Behaviour disorder ": 28.10895719829128, "Caesarean section ": 6.80543562182607, "Change in seizure presentation ": 211.97863648775075, "Cognitive disorder ": 6.431018476859681, "Crying ": 2.861832751141752, "Depressed mood ": 4.787762008082611, "Depression ": 4.602895454458997, "Diplopia ": 4.293936965457269, "Disturbance in attention ": 2.0470913145914893, "Drug ineffective ": 2.0195442651839968, "Drug ineffective for unapproved indication ": 2.8059422310693307, "Drug level increased ": 5.952001614153716, "Emotional disorder ": 11.873902606605606, "Epilepsy ": 8.227052707751023, "Fear ": 4.423033777376481, "Feeling abnormal ": 2.2386485032631054, "Focal dyscognitive seizures ": 42.01311000489026, "Generalised tonic-clonic seizure ": 20.591159463133124, "Hallucination ": 2.119041677049975, "Hallucination, auditory ": 6.941085502194045, "Hallucination, visual ": 4.108361007717854, "Hemiparesis ": 4.707708162999949, "Hemiplegia ": 4.514095045470783, "Hypersomnia ": 4.346983317038889, "Inability to afford medication ": 25.330867579726952, "Insomnia ": 2.1775347078402607, "Intentional product misuse ": 3.397187050680177, "Intentional self-injury ": 2.650526862832382, "Irritability ": 11.55014830485317, "Maternal exposure before pregnancy ": 46.264772324014366, "Maternal exposure during pregnancy ": 6.396402171704837, "Memory impairment ": 2.874098043810729, "Mental disorder ": 3.498861890931292, "Mood altered ": 6.038663098525994, "Mood swings ": 12.34908179675857, "Multiple-drug resistance ": 61.94275572432765, "Muscle twitching ": 3.130991179562926, "Myoclonus ": 3.048821133390644, "Nervousness ": 2.0987424382245714, "Off label use ": 5.521909550815612, "Overdose ": 5.791951032843361, "Paranoia ": 5.753530859635969, "Partial seizures ": 43.44448147852698, "Petit mal epilepsy ": 26.51918637846004, "Postoperative wound infection ": 15.260027866893164, "Prescribed overdose ": 5.712132665153324, "Product availability issue ": 27.22052828453979, "Product dose omission issue ": 2.3275274622840216, "Product use issue ": 3.065214551849517, "Psychomotor hyperactivity ": 7.345755108065209, "Psychotic disorder ": 13.540948584665262, "Screaming ": 8.222162567088276, "Sedation ": 6.363103093538912, "Seizure ": 17.048341765179778, "Seizure cluster ": 91.35430651773312, "Self-destructive behaviour ": 18.1784230792798, "Sleep disorder ": 3.0024006413297077, "Somnolence ": 3.7794468364786327, "Staphylococcal infection ": 2.374634012613188, "Status epilepticus ": 23.69646905937574, "Sudden unexplained death in epilepsy ": 107.99430888683808, "Suicidal behaviour ": 14.35262861933545, "Suicidal ideation ": 11.144015421193409, "Therapeutic response unexpected ": 2.543404012021999, "Therapy interrupted ": 31.92832533302308, "Thinking abnormal ": 5.448614885860769, "Tonic convulsion ": 25.358977684173944, "Underdose ": 6.090769037701363, "Unevaluable event ": 2.3992235556479544, "Urinary incontinence ": 4.584272025615266, "Wrong technique in product usage process ": 2.4779219780893005}
\ No newline at end of file
+{"Acute kidney injury": 2.6173348880947844, "Confusional state": 2.592223063147274, "Drug ineffective": 2.720521768876337, "Eye irritation": 67.0115553044586, "Eye pain": 12.531858574035065, "Intraocular pressure increased": 183.10262380635325, "Ocular hyperaemia": 30.48440017252974, "Somnolence": 3.783715157879208, "Toxicity to various agents": 3.4608334187773164, "Vision blurred": 4.520321914987699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/203.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/203.json
index eb96bb8d2e3..50805f54345 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/203.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/203.json
@@ -1 +1 @@
-{"Psoriasis ": 38.37623437383036}
\ No newline at end of file
+{"Abnormal dreams": 12.155831564315122, "Abnormal weight gain": 3.0102480819723496, "Accommodation disorder": 6.154651916865296, "Acne": 2.73425575782792, "Aggression": 5.00494041959586, "Agitation": 4.180714102724107, "Akathisia": 4.58741975998071, "Alcohol interaction": 5.069399028183685, "Anger": 4.140379681509965, "Anorgasmia": 41.679074451275135, "Anxiety": 3.809604640631152, "Apathy": 4.064880602334195, "Appetite disorder": 2.050391132463256, "Binge eating": 20.21125608828801, "Bipolar I disorder": 7.102179139056311, "Blood prolactin increased": 10.897428039078886, "Bradykinesia": 3.7487171074295382, "Bradyphrenia": 2.0977684236123024, "Bruxism": 23.684387230913103, "Circumstance or information capable of leading to medication error": 3.909133550941223, "Completed suicide": 2.343707860112936, "Constipation": 2.207277202241732, "Crying": 4.090818703878639, "Daydreaming": 5.254104222801221, "Depersonalisation/derealisation disorder": 10.093640961634778, "Depressed mood": 3.3638321426858155, "Depression": 2.0184559322062494, "Depressive symptom": 5.526911880620103, "Derealisation": 21.688081783999355, "Dissociation": 5.055675260022924, "Disturbance in sexual arousal": 11.356695192269145, "Dry eye": 2.3305677580868176, "Dry mouth": 2.009963905536199, "Dyspepsia": 2.672684392272187, "Ecchymosis": 4.045384670254833, "Ejaculation delayed": 35.3867920741629, "Ejaculation disorder": 4.486697194849922, "Ejaculation failure": 5.541015208402039, "Electric shock sensation": 3.7844405846401417, "Electrocardiogram QT prolonged": 2.483161604721336, "Emotional poverty": 6.7753003617441445, "Energy increased": 4.006684959264616, "Erectile dysfunction": 4.463882516976432, "Fear": 2.8320980855035085, "Feeling abnormal": 3.0839374162801056, "Feeling drunk": 2.599679390686197, "Feeling of despair": 5.15906391419491, "Food craving": 6.906699016369921, "Formication": 2.7840778297103115, "Galactorrhoea": 3.7954394802651295, "Gastrointestinal pain": 2.3076452667621603, "Genital hypoaesthesia": 15.103086320626188, "Hallucination, auditory": 2.5964264790287035, "Head discomfort": 2.297322009021695, "Homicidal ideation": 3.4157772754844067, "Hot flush": 2.4382160883635016, "Hunger": 9.737933802106646, "Hyperhidrosis": 2.0147352164818577, "Hyperprolactinaemia": 7.251190203791279, "Hypomania": 13.208859086668689, "Hyponatraemia": 3.236194217744348, "Impulsive behaviour": 5.061884232596684, "Inappropriate antidiuretic hormone secretion": 2.944094417583337, "Increased appetite": 8.301213626368801, "Increased tendency to bruise": 2.5082444988082977, "Indifference": 11.855333718343385, "Initial insomnia": 7.180102541672565, "Injection site haematoma": 2.916904876901613, "Injection site inflammation": 3.5173460119468154, "Injection site swelling": 2.1798499880684754, "Injection site warmth": 2.556511512645328, "Insomnia": 2.7486107994025386, "Intentional overdose": 2.1004933188735357, "Intentional self-injury": 4.236518316439188, "Irritability": 4.6782296275476245, "Libido decreased": 19.34528017098241, "Libido increased": 6.58355243381453, "Logorrhoea": 5.060702051876048, "Loss of libido": 8.51980123898211, "Major depression": 4.344682599792273, "Mania": 7.674561732956182, "Mental fatigue": 3.3071847642044814, "Middle insomnia": 2.779059025093731, "Mood altered": 3.076159165669891, "Mood swings": 2.0563012662870475, "Motion sickness": 5.254104222801221, "Muscle tightness": 2.171008144194178, "Mydriasis": 2.8025792774481, "Nausea": 3.864650233621023, "Negative thoughts": 21.19624265151812, "Nervousness": 3.5577229908414343, "Night sweats": 5.216931213750459, "Nightmare": 7.466262552079308, "Obsessive thoughts": 8.212337002231926, "Orgasm abnormal": 35.62027605040725, "Panic attack": 3.246288600003654, "Panic disorder": 2.404114238993878, "Panic reaction": 2.618845466786256, "Persecutory delusion": 2.835190480335049, "Poisoning deliberate": 2.8197664097533965, "Poor quality sleep": 3.248654445862769, "Pregnancy": 6.605794418634002, "Prescribed overdose": 3.657579581639872, "Product administered to patient of inappropriate age": 3.7987937859196346, "Product use in unapproved indication": 3.741314972788296, "Pruritus": 4.449183710349074, "Psychomotor hyperactivity": 5.592674637258802, "Reaction to excipient": 17.125858481015793, "Restless legs syndrome": 6.115806096278832, "Restlessness": 4.044732120258892, "Salivary hypersecretion": 4.417301114937845, "Sedation": 2.305000806658024, "Self-destructive behaviour": 6.344522301858557, "Self-injurious ideation": 15.49325200341054, "Serotonin syndrome": 14.714037263961462, "Sexual dysfunction": 23.5655207637592, "Sleep disorder": 2.5197098276075853, "Social avoidant behaviour": 3.576036908366408, "Somnambulism": 3.294857358142008, "Somnolence": 2.151983046952895, "Subcutaneous haematoma": 4.774042756664849, "Suicidal behaviour": 4.286341275558114, "Suicidal ideation": 10.875750222255917, "Suicide attempt": 3.645527779755001, "Tachyphrenia": 14.891530403737285, "Tearfulness": 2.1929907249524843, "Tension": 8.625032770510163, "Tension headache": 2.391071665599936, "Therapeutic response unexpected": 2.7738746172496165, "Therapy cessation": 14.98936002329755, "Therapy change": 5.405866799562959, "Thinking abnormal": 3.491508406348056, "Tic": 6.387545678153426, "Treatment noncompliance": 2.391842666124485, "Underdose": 3.5769198695696183, "Urinary retention": 2.126641550868607, "Vertigo": 2.4630935310825586, "Vomiting": 2.321350005468682, "Weight increased": 3.8792428944923856, "Withdrawal syndrome": 2.69585289466456, "Wrong patient": 22.745734156017445, "Wrong technique in product usage process": 4.644320877697612}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/204.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/204.json
index 4e96f91d613..0d5bbcc7398 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/204.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/204.json
@@ -1 +1 @@
-{"Anterior chamber cell ": 379.5394755689658, "Anterior chamber flare ": 402.1795221334658, "Anterior chamber inflammation ": 657.2409346490258, "Blindness ": 40.06329091219243, "Blindness transient ": 30.42786773225056, "Detachment of retinal pigment epithelium ": 498.59283968601534, "Endophthalmitis ": 48.52307633803014, "Eye inflammation ": 266.51048458961844, "Eye pain ": 35.02150537037874, "Idiopathic orbital inflammation ": 2660.372760591177, "Intraocular pressure increased ": 62.04947902726558, "Iridocyclitis ": 521.3094560837853, "Keratic precipitates ": 427.41863587669104, "Ocular hyperaemia ": 62.23780902167999, "Product use in unapproved indication ": 5.372244136762104, "Retinal artery occlusion ": 189.09444054438305, "Retinal haemorrhage ": 50.36075305203824, "Retinal occlusive vasculitis ": 1008.7292465087723, "Retinal oedema ": 250.10108620946292, "Retinal pigment epithelial tear ": 366.5736579907837, "Retinal vascular occlusion ": 337.6209236249197, "Retinal vasculitis ": 1058.3681285443824, "Subretinal fluid ": 590.32492324649, "Uveitis ": 142.12030696636904, "Vision blurred ": 18.03831414607306, "Visual acuity reduced ": 129.35655425693488, "Visual impairment ": 17.66306922815562, "Vitreous floaters ": 392.4118346221145, "Vitreous opacities ": 131.73476936043124, "Vitritis ": 1358.4940564151543}
\ No newline at end of file
+{"Intraocular pressure increased": 184.02015038649944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/205.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/205.json
index 468e6f635fc..c641955ec07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/205.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/205.json
@@ -1 +1 @@
-{"Atrial fibrillation ": 3.573149110231776, "Blood lactate dehydrogenase increased ": 15.394581403588946, "Contusion ": 9.074132003070314, "Disease progression ": 12.037425945531531, "Gastrointestinal disorder ": 3.1733214865609853, "Haemoglobin decreased ": 4.378308385204996, "Haemorrhage ": 3.0681788348271937, "Haemorrhage subcutaneous ": 42.19485753973184, "Myelodysplastic syndrome ": 19.880619736329056, "Myelosuppression ": 22.305217271544183, "Neutropenia ": 2.9270957471547145, "Neutrophil count decreased ": 3.985331950813275, "Off label use ": 10.071964209180356, "Petechiae ": 8.51423323903242, "Platelet count decreased ": 7.15903087668843, "Prescribed underdose ": 37.800265656865406, "Sepsis ": 2.863726747743638, "Underdose ": 17.415428879345832, "White blood cell count decreased ": 4.685050467870497, "White blood cell count increased ": 10.605860697292952}
\ No newline at end of file
+{"Abnormal behaviour": 16.6327666826383, "Adverse drug reaction": 7.406526535955066, "Affective disorder": 15.975556950926018, "Aggression": 13.718824718970282, "Anger": 8.412027317854058, "Anticonvulsant drug level increased": 53.10643467084547, "Behaviour disorder": 31.83180048056962, "Coagulopathy": 11.621960265885397, "Cognitive disorder": 11.773118964915284, "Delirium": 2.9891997513517103, "Depressed mood": 5.250185683210288, "Depression": 3.860691487296666, "Drug ineffective": 3.706574344639576, "Drug ineffective for unapproved indication": 19.57758478632129, "Drug intolerance": 3.0202577624951927, "Drug resistance": 9.846605225472588, "Dysarthria": 3.353894036007678, "Dystonia": 7.855907506312775, "Epilepsy": 11.911218636710496, "Exposure during pregnancy": 3.41206712951712, "Foetal exposure during pregnancy": 2.727986055011248, "Gait disturbance": 2.176409916859328, "Generalised tonic-clonic seizure": 8.376903608315061, "Gingival disorder": 47.87628306976799, "Hallucination": 4.337772292008388, "Hallucination, visual": 4.354156378080129, "Hyponatraemia": 3.1231792000907967, "Intestinal atresia": 1301.3554673539454, "Irritability": 9.978643256492289, "Maternal exposure before pregnancy": 55.54997841708654, "Maternal exposure during breast feeding": 31.63918674749975, "Maternal exposure during pregnancy": 13.402411002774071, "Memory impairment": 6.0700529536339065, "Mood swings": 8.259207953150085, "Multiple-drug resistance": 383.9333592629885, "Myoclonic epilepsy": 80.28682712562556, "Myoclonus": 12.946037358036394, "Nephrolithiasis": 2.759663047232106, "Off label use": 7.777695156773269, "Overdose": 9.244613032529807, "Oxygen saturation decreased": 2.022583433238143, "Partial seizures": 13.619399023248173, "Partial seizures with secondary generalisation": 610.7360466308605, "Patent ductus arteriosus": 53.23991995776781, "Petit mal epilepsy": 23.244622915869808, "Postictal paralysis": 345.63629709145465, "Premature baby": 11.030295800604376, "Premature delivery": 24.3147215911612, "Prescribed overdose": 4.52465246155034, "Product use in unapproved indication": 2.515002386031213, "Product use issue": 3.796214371767524, "Psychotic disorder": 3.146909279314742, "Pulmonary haemorrhage": 17.43455959639538, "Respiratory arrest": 3.03289447280678, "Salivary hypersecretion": 9.202114483795578, "Seizure": 16.778888356672024, "Somnolence": 3.6738493764717535, "Speech disorder": 2.9433795418342923, "Status epilepticus": 79.90432061527258, "Suicidal ideation": 5.3183167014938695, "Therapeutic product effect incomplete": 2.8306722230930075, "Therapeutic product ineffective for unapproved indication": 625.9010999964784, "Therapeutic response unexpected": 12.308380398785625, "Therapy non-responder": 3.302794126279816, "Treatment failure": 2.2359148514497305, "Underdose": 5.9146100755234645, "Weight increased": 4.52689709748678}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/206.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/206.json
index 6be27c95757..4bfe0c72cba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/206.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/206.json
@@ -1 +1 @@
-{"Drug ineffective ": 3.920547473327615, "Epilepsy ": 15.45352692017746, "Off label use ": 2.345528044019679, "Product use issue ": 10.439739296252949, "Respiratory arrest ": 27.030711394120697, "Respiratory depression ": 166.99216145940065, "Seizure ": 8.831169785531339, "Somnolence ": 5.271483754993824, "Status epilepticus ": 66.22376736825215}
\ No newline at end of file
+{"Abnormal behaviour": 4.2286544214840704, "Adverse drug reaction": 7.657926244819743, "Adverse event": 4.620994882885323, "Affective disorder": 48.848659447160486, "Aggression": 21.39616270142542, "Agitation": 3.67304783014517, "Anger": 14.593799580341882, "Anxiety": 2.6102226933160275, "Apathy": 4.902148692531389, "Aphasia": 2.0316948037832887, "Ataxia": 2.857977774886954, "Atonic seizures": 65.32405116475624, "Aura": 86.71754002694297, "Balance disorder": 3.756276233966533, "Behaviour disorder": 28.10895719829128, "Caesarean section": 6.80543562182607, "Change in seizure presentation": 211.97863648775075, "Cognitive disorder": 6.431018476859681, "Crying": 2.861174513604004, "Depressed mood": 4.787762008082611, "Depression": 4.602895454458997, "Diplopia": 4.293936965457269, "Disturbance in attention": 2.0470913145914893, "Drug ineffective": 2.019529327986649, "Drug ineffective for unapproved indication": 2.8059422310693307, "Drug level increased": 5.952001614153716, "Emotional disorder": 11.873902606605606, "Epilepsy": 8.227052707751023, "Fear": 4.423033777376481, "Feeling abnormal": 2.2386053915901174, "Focal dyscognitive seizures": 42.01311000489026, "Generalised tonic-clonic seizure": 20.591159463133124, "Hallucination": 2.119041677049975, "Hallucination, auditory": 6.941085502194045, "Hallucination, visual": 4.108361007717854, "Hemiparesis": 4.707114367201571, "Hemiplegia": 4.514095045470783, "Hypersomnia": 4.346983317038889, "Inability to afford medication": 25.330867579726952, "Insomnia": 2.1775347078402607, "Intentional product misuse": 3.397187050680177, "Intentional self-injury": 2.650526862832382, "Irritability": 11.549594880680846, "Maternal exposure before pregnancy": 46.264772324014366, "Maternal exposure during pregnancy": 6.396402171704837, "Memory impairment": 2.874098043810729, "Mental disorder": 3.498861890931292, "Mood altered": 6.038663098525994, "Mood swings": 12.34908179675857, "Multiple-drug resistance": 61.94275572432765, "Muscle twitching": 3.130991179562926, "Myoclonus": 3.048821133390644, "Nervousness": 2.0987424382245714, "Off label use": 5.521691705852038, "Overdose": 5.791951032843361, "Paranoia": 5.753530859635969, "Partial seizures": 43.44448147852698, "Petit mal epilepsy": 26.51918637846004, "Postoperative wound infection": 15.260027866893164, "Prescribed overdose": 5.712132665153324, "Product availability issue": 27.22052828453979, "Product dose omission issue": 2.3275274622840216, "Product use issue": 3.065214551849517, "Psychomotor hyperactivity": 7.344484520443719, "Psychotic disorder": 13.540948584665262, "Screaming": 8.222162567088276, "Sedation": 6.363103093538912, "Seizure": 17.046442053749782, "Seizure cluster": 91.35430651773312, "Self-destructive behaviour": 18.1784230792798, "Sleep disorder": 3.0024006413297077, "Somnolence": 3.779405130394795, "Staphylococcal infection": 2.374634012613188, "Status epilepticus": 23.69646905937574, "Sudden unexplained death in epilepsy": 107.99430888683808, "Suicidal behaviour": 14.35262861933545, "Suicidal ideation": 11.144015421193409, "Therapeutic response unexpected": 2.543404012021999, "Therapy interrupted": 31.92832533302308, "Thinking abnormal": 5.448614885860769, "Tonic convulsion": 25.358977684173944, "Underdose": 6.090769037701363, "Unevaluable event": 2.3992235556479544, "Urinary incontinence": 4.584272025615266, "Wrong technique in product usage process": 2.4779219780893005}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/207.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/207.json
index 62d088671dc..d0a5ccdd310 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/207.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/207.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.7281098337410583, "Acquired factor V deficiency ": 117.87009940609104, "Acute graft versus host disease ": 10.937897834987767, "Adenovirus infection ": 14.149599972022587, "Adrenal insufficiency ": 6.692390531629411, "Adrenal suppression ": 19.06480719381573, "Adrenocortical insufficiency acute ": 12.03952252084461, "Adverse drug reaction ": 4.845263320068497, "Alcoholism ": 4.011405458055314, "Alternaria infection ": 116.07700445778656, "Anaemia ": 3.160259205502261, "Anal fissure ": 2.206837254518756, "Angiopathy ": 4.842038965436102, "Arthropod bite ": 2.5485373583746287, "Aspergillus infection ": 6.046332538424179, "Asphyxia ": 3.01882622423519, "Aspiration ": 16.01186398816886, "Asthma ": 15.281180047135278, "Asthmatic crisis ": 5.277310821590377, "BK virus infection ": 10.203487494510412, "Blood calcium increased ": 20.55414381138715, "Blood corticotrophin decreased ": 13.218166422979383, "Blood immunoglobulin E increased ": 58.39619944542872, "Blood lactic acid increased ": 30.42592214966272, "Blood potassium decreased ": 11.539567980308808, "Blood test abnormal ": 13.25760628901097, "Body height decreased ": 2.1800557778595326, "Botulism ": 41.0277891035544, "Bradyarrhythmia ": 2.038666637566187, "Brain herniation ": 2.1818265966283708, "Breath sounds abnormal ": 37.50732027537634, "Bronchial hyperreactivity ": 3.243989488013666, "Bronchial secretion retention ": 11.93272844282886, "Bronchiectasis ": 20.224923658887302, "Bronchitis ": 2.2416119731510604, "Bronchitis bacterial ": 23.353372908367465, "Bronchopulmonary aspergillosis ": 2.845877586195064, "Bronchopulmonary aspergillosis allergic ": 153.45661151596155, "Butterfly rash ": 17.71583457045738, "Cardiac valve disease ": 2.58313229049446, "Central obesity ": 5.2225073673943845, "Chest X-ray abnormal ": 50.14859097325539, "Chest discomfort ": 4.061523130104637, "Cholangitis sclerosing ": 4.216534438585718, "Chronic obstructive pulmonary disease ": 3.016430261531852, "Chronic sinusitis ": 112.51583371359511, "Chronic spontaneous urticaria ": 4.5680235817592045, "Coagulation factor V level abnormal ": 90.7661990756028, "Coagulation factor deficiency ": 54.2234253806371, "Colitis ": 19.987251479899147, "Colitis microscopic ": 7.962968678799189, "Colitis ulcerative ": 21.63333768729744, "Computerised tomogram abnormal ": 2.1092936503162014, "Conduction disorder ": 2.7118645190785005, "Congenital anomaly ": 2.2536665605845343, "Constipation ": 5.4187079348240506, "Cortisol decreased ": 11.5595213797682, "Cough ": 3.284822843664112, "Crohn's disease ": 4.224170457115733, "Cryptococcosis ": 10.471984647199964, "Cushing's syndrome ": 15.412178040556698, "Cushingoid ": 7.706254919484505, "Cystitis haemorrhagic ": 4.282378186855326, "Cytokine storm ": 5.149095734758227, "Cytomegalovirus colitis ": 2.847438057283888, "Cytomegalovirus infection reactivation ": 4.360581559156878, "Defaecation urgency ": 5.343920771832232, "Diastolic dysfunction ": 3.90560225138258, "Distractibility ": 7.609857396754732, "Drug hypersensitivity ": 2.7920262670521967, "Drug ineffective ": 2.271144149479289, "Dyspepsia ": 6.910705238992231, "Dysphonia ": 4.344311172158866, "Dyspnoea ": 2.408192003674299, "Dyspnoea exertional ": 2.104296114538529, "Ear pruritus ": 56.23921834332768, "Ectropion ": 52.61492340295462, "Electrocardiogram repolarisation abnormality ": 6.127680521598452, "Embolism venous ": 5.155983529678085, "Emphysema ": 6.315109050383659, "Encephalitis cytomegalovirus ": 29.76743538949785, "Eosinophil count decreased ": 17.98692140487221, "Eosinophil count increased ": 13.470282246746612, "Eosinophilia ": 14.72099839335945, "Eosinophilic bronchitis ": 119.2452919568111, "Eosinophilic granulomatosis with polyangiitis ": 6.107953468187922, "Epstein-Barr viraemia ": 13.848991843215988, "Epstein-Barr virus infection reactivation ": 2.526336161558552, "Erythema ": 2.5688492003266643, "Eye pruritus ": 13.3830850288487, "Eyelid disorder ": 3.831470974777136, "Factor V Leiden mutation ": 44.04725409756571, "Faecal calprotectin increased ": 16.052752804414364, "Female genital tract fistula ": 137.99235345300835, "Forced expiratory volume decreased ": 4.436987903468998, "Forced vital capacity decreased ": 10.345550596987223, "Frequent bowel movements ": 40.49133881938085, "Full blood count abnormal ": 34.05147075057828, "Gastrointestinal inflammation ": 2.21165704363644, "Gastrointestinal ulcer ": 5.328398887963538, "Gastrooesophageal reflux disease ": 8.674658844538305, "Graft versus host disease ": 2.4085773892941043, "Graft versus host disease in gastrointestinal tract ": 12.768010759117397, "Graft versus host disease in liver ": 10.783336630377672, "Graft versus host disease in skin ": 10.127750003212604, "Growth failure ": 37.27284409884139, "Growth retardation ": 8.20655810009678, "Haematochezia ": 13.371931013562667, "Haemoptysis ": 4.195273060025049, "Haemothorax ": 7.928519619769921, "Head deformity ": 15.85349694615426, "Hiatus hernia ": 2.247945742895284, "Human herpesvirus 6 infection ": 5.109612800459093, "Hyperglycaemia ": 3.639015147468984, "Hypogammaglobulinaemia ": 5.500930288797684, "Hyporeflexia ": 2.0737408933281296, "Hypothalamic pituitary adrenal axis suppression ": 16.521413989303944, "Hypovolaemia ": 5.967726970506194, "Hypoxia ": 3.898813490122389, "Hysterectomy ": 3.5367053072578023, "Ill-defined disorder ": 4.195023227944715, "Impaired quality of life ": 3.329062205197135, "Impulsive behaviour ": 2.3161080491186343, "Increased anteroposterior chest diameter ": 106.1072779793699, "Inflammatory bowel disease ": 2.0872131448249704, "Infusion related reaction ": 11.422271630851982, "Inhibitory drug interaction ": 3.437052385875562, "Inspiratory capacity decreased ": 79.49867101686598, "Intentional device misuse ": 2.7832979154744653, "Judgement impaired ": 5.5476410451567295, "Lacrimation increased ": 10.119016008498214, "Laryngeal stenosis ": 509.27007122432354, "Latent tuberculosis ": 3.7720725446389554, "Liver function test increased ": 4.607044378644615, "Loss of personal independence in daily activities ": 9.87751215182506, "Lower respiratory tract infection ": 4.082520661691011, "Lung diffusion test abnormal ": 867.5748060901936, "Lung disorder ": 5.618856803494375, "Lung opacity ": 24.30746981198156, "Macular degeneration ": 56.74452833179084, "Mechanical ventilation complication ": 86.36942001783544, "Middle insomnia ": 16.581529434744848, "Mite allergy ": 2.687102036427533, "Mucous stools ": 2.446321606411439, "Multiple allergies ": 12.952186524893628, "Nasal congestion ": 6.792136139986357, "Nasal obstruction ": 15.042057198826114, "Nasal polyps ": 65.25688218887255, "Neutrophilia ": 5.577794789043273, "Obstructive airways disorder ": 36.60759271961302, "Oesophageal disorder ": 2.9723899984242563, "Oligoarthritis ": 13.786102168972665, "Oral candidiasis ": 40.83840925748972, "Oropharyngeal candidiasis ": 4.836272419919271, "Paraesthesia oral ": 16.55266269558192, "Periorbital oedema ": 2.350837245469499, "Pharyngitis streptococcal ": 8.703536075529568, "Platelet count increased ": 20.795334418912905, "Pleural effusion ": 2.1121270573677804, "Pleuritic pain ": 24.903057756599843, "Pneumonia viral ": 5.517517911099858, "Pneumothorax ": 3.869506655743951, "Polyp ": 4.7789135698057725, "Pouchitis ": 22.065366433820596, "Procedural pain ": 61.97940338329205, "Proctitis ": 109.54358055323075, "Productive cough ": 3.0758212251814405, "Pseudo Cushing's syndrome ": 15.599294521545328, "Pulmonary fibrosis ": 6.52703828822927, "Pulmonary function test abnormal ": 115.08364956321054, "Pulmonary mass ": 8.883982298328002, "Radiculopathy ": 92.01664958753116, "Rales ": 9.172967144451034, "Rectal haemorrhage ": 12.827201639878952, "Respiratory symptom ": 4.248392906182893, "Respiratory syncytial virus infection ": 5.057234879258614, "Respiratory tract infection ": 2.0575917018166408, "Reversible airways obstruction ": 37.98496758565716, "Rhinitis allergic ": 28.37765729441456, "Rhinorrhoea ": 4.8169666719002615, "Rhonchi ": 5.614708455050379, "Salpingo-oophorectomy unilateral ": 142.27412353519566, "Secondary adrenocortical insufficiency ": 2.69330128717895, "Secretion discharge ": 2.8572194683161114, "Septic embolus ": 6.395338562829599, "Shock haemorrhagic ": 2.088468596141406, "Sinonasal obstruction ": 9.28894856334398, "Sinus disorder ": 28.029947910834515, "Sinus polyp ": 87.35260589729205, "Sinusitis ": 3.0424069475120654, "Sinusitis fungal ": 43.91451549086277, "Skin lesion ": 6.900106337972303, "Skin striae ": 3.0074910778341315, "Skin test positive ": 6.527595711168761, "Sleep disorder due to a general medical condition ": 25.56865674664422, "Sneezing ": 11.887005014778293, "Sputum culture positive ": 62.3514180663762, "Sputum discoloured ": 10.178126069238433, "Sputum increased ": 3.248305317497433, "Staphylococcal sepsis ": 2.7257276833259088, "Stenotrophomonas infection ": 27.50088727671389, "Suspected suicide ": 2.924468233689423, "Synovial cyst ": 2.099130133272767, "Systemic mycosis ": 36.30205167735398, "Tachypnoea ": 4.012604339831779, "Therapeutic product effect incomplete ": 14.47211388881848, "Therapeutic response shortened ": 2.140309438262549, "Throat clearing ": 17.449373352666097, "Total lung capacity decreased ": 26.15753927417377, "Type 2 diabetes mellitus ": 13.39667373080051, "Upper respiratory fungal infection ": 202.2940538877336, "Upper-airway cough syndrome ": 78.61334216714505, "Use of accessory respiratory muscles ": 15.940698694820531, "Vaginal discharge ": 62.14163161807597, "Vaginal flatulence ": 168.708486554049, "Vasculitis ": 11.923071748185828, "Vena cava filter insertion ": 21.00359492613627, "Vital capacity decreased ": 36.50840408520065, "Vocal cord dysfunction ": 289.63836759828695, "Weight decreased ": 3.5607609082836653, "Wheezing ": 16.163702002149996}
\ No newline at end of file
+{"Psoriasis": 38.37623437383036}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/208.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/208.json
index dce82cbcec4..b2e2c3f4fb5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/208.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/208.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 6.596792511968096, "Acute kidney injury ": 13.430267475823124, "Aggression ": 4.057387510271644, "Amnesia ": 3.889045767515914, "Anxiety disorder ": 42.010011533516206, "Arteriosclerosis coronary artery ": 45.42836115240488, "Atrial fibrillation ": 6.616978752788126, "Blood cholesterol increased ": 2.059448774912401, "Blood creatinine increased ": 7.811397544718428, "Blood potassium increased ": 4.28868497506558, "Blood pressure systolic decreased ": 20.205542814212677, "Blood sodium decreased ": 4.240698395150697, "Blood urea increased ": 3.896770444755978, "Cardiac failure ": 9.040607814696198, "Cardiac failure acute ": 48.36291223594856, "Cardiac failure chronic ": 73.11199206741138, "Cardiac failure congestive ": 6.70058733729879, "Cardiomegaly ": 27.86399905350964, "Completed suicide ": 8.070966578345233, "Coronary artery disease ": 4.215655511604572, "Deafness ": 3.171814098222176, "Dehydration ": 5.133935545247482, "Dermatitis bullous ": 4.744126625006627, "Device malfunction ": 11.105642019747, "Device occlusion ": 41.90979623314222, "Drug dependence ": 2.483385532904476, "Drug withdrawal syndrome ": 5.3303540269639145, "Eating disorder ": 11.562453375194776, "Ejection fraction abnormal ": 37.77797055980027, "Ejection fraction decreased ": 7.202621769364409, "End stage renal disease ": 33.036327395440416, "Faeces discoloured ": 22.72127019674856, "Fluid retention ": 5.860197558167768, "Gait inability ": 5.126562271467251, "Gastrointestinal angiodysplasia ": 693.0067012441299, "Gastrointestinal haemorrhage ": 5.442925584424548, "Generalised oedema ": 6.6065137159538185, "Glomerular filtration rate decreased ": 5.943983092291953, "Gout ": 5.032878512166839, "Helicobacter infection ": 3.866311578004487, "Hospitalisation ": 2.973341954330259, "Hyperkalaemia ": 14.939793212633624, "Hypernatraemia ": 19.02080233809311, "Hypervolaemia ": 9.80238224509852, "Hypokalaemia ": 6.936315030390356, "Hypokinesia ": 5.565785141340589, "Hypomagnesaemia ": 21.3094339833183, "Hyponatraemia ": 4.37472754916349, "Hypotension ": 3.884213705071484, "Hypovolaemia ": 61.97871648184076, "Impaired driving ability ": 29.19821471069218, "Incarcerated hernia ": 1443.7830846389747, "Incorrect dose administered ": 3.149264068794942, "International normalised ratio increased ": 8.493334721022391, "Interstitial lung disease ": 3.851261225899821, "Iron deficiency anaemia ": 9.453690296989397, "Left atrial dilatation ": 462.6818693399988, "Left ventricular dilatation ": 312.61300321709945, "Lethargy ": 3.227079935636893, "Lumbar spinal stenosis ": 111.1047198134594, "Lung hyperinflation ": 424.4136683948769, "Meningitis ": 24.377082120436363, "Mitral valve incompetence ": 42.96962464155932, "Multiple organ dysfunction syndrome ": 3.3194734821854173, "Oedema peripheral ": 4.564941762235514, "Orthostatic hypotension ": 6.8192639134782285, "Overdose ": 6.872812829955204, "Pneumonia ": 2.256293411654253, "Product administration error ": 2.331609469460284, "Psychotic behaviour ": 171.91699021283188, "Psychotic disorder ": 5.855314795899114, "Pulmonary congestion ": 30.546038460782796, "Pulmonary hypertension ": 3.4243357696157606, "Renal impairment ": 5.614002666269199, "Right atrial dilatation ": 556.5390627621568, "Speech disorder ": 4.223316646849057, "Spinal cord abscess ": 1024.6447354191264, "Substance abuse ": 10.415776977316725, "Toxicity to various agents ": 9.163239687410714, "Urine output decreased ": 7.375202630350306, "Ventricular tachycardia ": 7.952151309760993}
\ No newline at end of file
+{"Anterior chamber cell": 379.5394755689658, "Anterior chamber flare": 402.1795221334658, "Anterior chamber inflammation": 657.2409346490258, "Blindness": 40.06329091219243, "Blindness transient": 30.42786773225056, "Detachment of retinal pigment epithelium": 498.59283968601534, "Endophthalmitis": 48.52307633803014, "Eye inflammation": 266.51048458961844, "Eye pain": 35.02150537037874, "Idiopathic orbital inflammation": 2660.372760591177, "Intraocular pressure increased": 62.04947902726558, "Iridocyclitis": 521.3094560837853, "Keratic precipitates": 427.41863587669104, "Ocular hyperaemia": 62.23780902167999, "Product use in unapproved indication": 5.372076572496315, "Retinal artery occlusion": 189.09444054438305, "Retinal haemorrhage": 50.36075305203824, "Retinal occlusive vasculitis": 1008.7292465087723, "Retinal oedema": 250.10108620946292, "Retinal pigment epithelial tear": 366.5736579907837, "Retinal vascular occlusion": 337.6209236249197, "Retinal vasculitis": 1058.3681285443824, "Subretinal fluid": 590.32492324649, "Uveitis": 142.12030696636904, "Vision blurred": 18.03831414607306, "Visual acuity reduced": 129.35655425693488, "Visual impairment": 17.66306922815562, "Vitreous floaters": 392.4118346221145, "Vitreous opacities": 131.73476936043124, "Vitritis": 1358.4940564151543}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/209.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/209.json
index 32887a93315..9f88becd18e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/209.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/209.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 3.0589886708459497, "Abnormal loss of weight ": 7.009046843402321, "Adverse drug reaction ": 3.165648983819231, "Anaesthetic complication ": 23.08850381165105, "Anal incontinence ": 8.944729713295086, "Anterior spinal artery syndrome ": 886.5884144463513, "Apnoea ": 8.643477787121533, "Arachnoiditis ": 122.6566059986434, "Areflexia ": 21.26904191385626, "Arteriospasm coronary ": 7.463881350510869, "Back pain ": 3.996373404203416, "Benign prostatic hyperplasia ": 7.875061063209982, "Blood pressure decreased ": 3.9405904733346646, "Bradycardia ": 5.34914881292289, "Bradycardia foetal ": 44.37727052545057, "Brain herniation ": 11.88314795847874, "Burning sensation ": 2.494994152406536, "Cardiac arrest ": 4.18691754692918, "Cauda equina syndrome ": 182.106144403854, "Cerebrospinal fluid leakage ": 28.234465703890127, "Complex regional pain syndrome ": 19.028176756671066, "Complication associated with device ": 8.58755153109131, "Constipation ": 2.2075080426635867, "Coordination abnormal ": 2.0789379737135074, "Crepitations ": 41.77879428716924, "Cyanosis ": 4.441604940448888, "Decubitus ulcer ": 8.954260144522411, "Delayed recovery from anaesthesia ": 22.254812764510696, "Delirium ": 5.600010579276528, "Depressed level of consciousness ": 3.588037867947536, "Device dislocation ": 14.97315013106873, "Device failure ": 9.6928166061272, "Device infusion issue ": 34.58683265480888, "Diplopia ": 4.695482313140665, "Discomfort ": 2.2305058301037506, "Drug delivery system malfunction ": 8.137558355126385, "Drug ineffective for unapproved indication ": 2.6802205026410437, "Drug withdrawal syndrome ": 15.95806483657304, "Dysuria ": 2.759067571221247, "Electric shock sensation ": 3.763583928994104, "Exposure during pregnancy ": 6.059204182388702, "Exposure via breast milk ": 11.285164732104995, "Extra dose administered ": 18.115234446117157, "Failed back surgery syndrome ": 511.034546531061, "Foetal death ": 4.481410437167599, "Foetal distress syndrome ": 10.926526119369782, "Foetal exposure during delivery ": 120.48872499744046, "Foetal exposure during pregnancy ": 6.0736251992950665, "Foetal growth restriction ": 15.9667231857266, "Formication ": 3.843513565322045, "Gait inability ": 3.013128516961692, "Generalised tonic-clonic seizure ": 2.4121734829440133, "Haemodynamic instability ": 6.406652284763241, "Heart rate decreased ": 2.0553981491596027, "Horner's syndrome ": 42.95057068080644, "Hospitalisation ": 2.5894959370326998, "Hyperaesthesia ": 7.909444522390193, "Hypoacusis ": 3.160002270525049, "Hypoaesthesia ": 2.6084091254059705, "Hypopnoea ": 9.75713982494687, "Hypotension ": 3.3459717183427045, "Hypothermia ": 2.909448883283917, "Hypoxia ": 3.679595413361564, "Implant site discharge ": 264.4832023807302, "Implant site extravasation ": 66.24372770902625, "Implant site infection ": 49.881796170019705, "Implant site pain ": 158.40017261745592, "Incorrect route of product administration ": 8.87393198142919, "Infusion site mass ": 273.9821206216226, "Intervertebral disc degeneration ": 6.85830655674908, "Ischaemia ": 6.122132805346811, "Kyphosis ": 93.82169501573098, "Labelled drug-drug interaction medication error ": 6.596760473311735, "Lethargy ": 2.432726387351796, "Libido decreased ": 6.772424126502291, "Live birth ": 17.03074081666323, "Local anaesthetic systemic toxicity ": 595.3668374268615, "Loss of consciousness ": 2.303789709968207, "Low birth weight baby ": 10.803296984130249, "Lumbar spinal stenosis ": 44.5916838596932, "Lung disorder ": 3.1614601372670603, "Magnetic resonance imaging abnormal ": 13.306867129314227, "Maternal exposure during breast feeding ": 10.322884496813666, "Maternal exposure during delivery ": 113.3381710601659, "Maternal exposure during pregnancy ": 7.964337031256709, "Medical device discomfort ": 290.63123174664247, "Medical observation ": 292.7905486857145, "Mental status changes ": 6.940268523046822, "Motor dysfunction ": 11.146037610263733, "Movement disorder ": 2.299846032202524, "Multiple sclerosis relapse ": 3.164214167574689, "Muscle rigidity ": 2.2008937839219853, "Muscle spasms ": 3.8031601164019535, "Muscle spasticity ": 27.123164643549632, "Muscle tightness ": 3.4367413629941663, "Muscular weakness ": 2.1269410675909977, "Musculoskeletal chest pain ": 2.1119878155979475, "Myoclonus ": 7.251053418117064, "Neonatal respiratory distress syndrome ": 9.997270337114802, "Neuralgia ": 6.505878910478043, "Neurotoxicity ": 4.582403595753855, "No adverse event ": 13.158126403706996, "Off label use ": 3.2234104539684734, "Ophthalmoplegia ": 89.29806148768498, "Overdose ": 3.840925020580722, "Oxygen saturation decreased ": 2.3652898150308777, "Pain ": 2.5481860456262657, "Paralysis ": 6.696687477025248, "Paraplegia ": 25.22604234464008, "Performance status decreased ": 45.97860329989782, "Postoperative wound infection ": 9.394036209693931, "Postpartum haemorrhage ": 41.72040540553686, "Pre-eclampsia ": 7.210381944502787, "Premature baby ": 14.973621523578668, "Premature delivery ": 17.04393497101173, "Prescribed overdose ": 6.7239760323819455, "Procedural pain ": 3.299795593688674, "Product administered to patient of inappropriate age ": 12.84518811127172, "Pulseless electrical activity ": 13.45264252630654, "Rales ": 9.968013946641769, "Respiratory acidosis ": 7.1224180833274175, "Respiratory arrest ": 3.562602185618342, "Respiratory depression ": 15.274017276246315, "Rhythm idioventricular ": 227.1405988061508, "Scab ": 3.5199129679088426, "Sedation ": 4.90970225699097, "Sedation complication ": 7.032081718116269, "Sensory disturbance ": 2.0445972817076647, "Sensory loss ": 7.999115264772319, "Sleep apnoea syndrome ": 3.3897731919806624, "Spinal compression fracture ": 17.581425787668437, "Spinal cord compression ": 10.348519821492088, "Spinal cord injury ": 83.65888203080559, "Spinal pain ": 3.986207676866142, "Spinal stenosis ": 12.82591703795982, "Strabismus ": 72.02881007937688, "Symmetrical drug-related intertriginous and flexural exanthema ": 71.44799938243642, "Therapeutic response decreased ": 9.231388280865772, "Therapy non-responder ": 12.400801590646443, "Underdose ": 3.375362282083454, "Unevaluable event ": 8.387640095625544, "Unresponsive to stimuli ": 8.090250159834946, "Urinary incontinence ": 2.994754400430537, "Urinary retention ": 6.604343248881143, "Uterine hypotonus ": 244.2284270762048, "Ventricular arrhythmia ": 12.487877859106089, "Ventricular extrasystoles ": 2.464671298135256, "Ventricular tachycardia ": 3.891210293591878, "Withdrawal syndrome ": 6.501143882900596}
\ No newline at end of file
+{"Atrial fibrillation": 3.573051576306949, "Blood lactate dehydrogenase increased": 15.394581403588946, "Contusion": 9.074132003070314, "Disease progression": 12.037425945531531, "Gastrointestinal disorder": 3.1732215726123765, "Haemoglobin decreased": 4.378308385204996, "Haemorrhage": 3.0681788348271937, "Haemorrhage subcutaneous": 42.19485753973184, "Myelodysplastic syndrome": 19.880619736329056, "Myelosuppression": 22.305217271544183, "Neutropenia": 2.9269698717288395, "Neutrophil count decreased": 3.985331950813275, "Off label use": 10.07156723927262, "Petechiae": 8.51423323903242, "Platelet count decreased": 7.15903087668843, "Prescribed underdose": 37.800265656865406, "Sepsis": 2.863726747743638, "Underdose": 17.415428879345832, "White blood cell count decreased": 4.685050467870497, "White blood cell count increased": 10.603829055390763}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/21.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/21.json
index 4f33a50e869..3169529f063 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/21.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/21.json
@@ -1 +1 @@
-{"Hypoglycaemia ": 7.467925153294567}
\ No newline at end of file
+{"Activated partial thromboplastin time prolonged": 9.794300711062869, "Analgesic therapy": 41.7137727036254, "Antacid therapy": 70.54966664321147, "Anticoagulant therapy": 42.63497667938178, "Aortic stenosis": 15.788116947577956, "Appendicitis": 5.725439129869816, "Appendicolith": 18.89066446471517, "Aspiration": 6.722209175374538, "Asthma": 16.034088047566755, "Asthma-chronic obstructive pulmonary disease overlap syndrome": 1026.0800915136883, "Ataxia": 17.626057577583772, "Atrial fibrillation": 3.6820600394103296, "Bacterial infection": 4.561052833094216, "Benign prostatic hyperplasia": 11.92723072463793, "Blood bilirubin increased": 13.905472518328969, "Blood calcium increased": 9.75717599082466, "Blood test abnormal": 13.871090054510477, "Breast conserving surgery": 133.00163975369662, "Breath sounds abnormal": 69.76869441116006, "Bronchial obstruction": 209.5070872558104, "Bronchial wall thickening": 160.32214726127918, "Bronchiectasis": 141.1567129153049, "Bronchiolitis": 16.175340456847515, "Bronchopulmonary aspergillosis allergic": 72.1848462799333, "Cardiac murmur": 60.81870293394235, "Cardiogenic shock": 3.63159670714588, "Carotid arteriosclerosis": 69.48812564852915, "Cataract": 10.95899860812604, "Cellulitis": 3.005973076695175, "Cholelithiasis": 24.42525250159686, "Chronic obstructive pulmonary disease": 29.154484678147117, "Chronic sinusitis": 20.93627173504365, "Condition aggravated": 4.230613060217498, "Coronary artery bypass": 51.48872669795927, "Cough": 2.0849780786417926, "Crepitations": 15.79355590154366, "Crohn's disease": 2.3477185887780525, "Dermatitis atopic": 92.34949312126048, "Dupuytren's contracture": 82.26474012607873, "Dupuytren's contracture operation": 4289.238193960354, "Dyspepsia": 5.982304367531809, "Dysphagia": 5.144541199056696, "Dyspnoea": 2.2146747274678558, "Dyspnoea exertional": 11.156041974721877, "Emphysema": 35.37101046229918, "Eosinophil count increased": 11.046773925916243, "Full blood count abnormal": 13.226810655026258, "Fungal disease carrier": 3630.822227419112, "Gastroenteritis": 31.08316455881353, "Gastrooesophageal reflux disease": 10.287800028280795, "Granuloma": 23.244855531122948, "Graves' disease": 12.300312738030945, "Haemoptysis": 2.286225686888364, "Hepatic enzyme increased": 6.53294544579161, "Hepatotoxicity": 21.478130648738183, "Hypercapnia": 87.65943224161082, "Hypertension": 2.0391333021842586, "Hypomania": 115.1590019708789, "Hypothyroidism": 2.0899723832883224, "Ill-defined disorder": 3.8833784063394505, "Impaired quality of life": 11.917003816073244, "Inguinal hernia repair": 924.4685547655546, "Jaundice cholestatic": 100.8431385813956, "Loss of personal independence in daily activities": 9.263379861637183, "Lower respiratory tract infection": 5.4037397425142055, "Lung diffusion disorder": 1409.8429305547263, "Lung diffusion test decreased": 155.189601036973, "Lung disorder": 7.157501990190728, "Lung neoplasm": 206.0748539316517, "Lung neoplasm malignant": 21.55655238078973, "Meniere's disease": 34.264617464400864, "Mycobacterium test positive": 272.05132804874165, "Nasal congestion": 7.64959702258826, "Nasal polyps": 140.08611178974064, "Nephrectomy": 38.63190251255492, "No adverse event": 2.033384056312953, "Nocturnal dyspnoea": 102.4710127386318, "Obstruction": 37.10626431864435, "Obstructive airways disorder": 38.78514261709207, "Oedema peripheral": 5.260040509435165, "Oral candidiasis": 5.240636219464246, "Oropharyngeal candidiasis": 342.6936893694759, "Oropharyngeal discomfort": 22.966397516323312, "Osteonecrosis of jaw": 17.730997735917917, "Pneumonia": 4.887498549939374, "Productive cough": 12.673877489259858, "Psychotic disorder": 17.783332048865734, "Pulmonary mass": 9.542625971180897, "Renal cyst": 9.99700219557947, "Respiratory disorder": 13.193316309498613, "Respiratory symptom": 41.88759750196953, "Rhinitis allergic": 73.9618636737396, "Sarcoidosis": 92.18287781947332, "Schizophrenia": 68.72433453293026, "Sinus disorder": 20.17617332845585, "Sinus pain": 15.256119622958796, "Sinusitis": 2.639619963303937, "Sleep disorder due to a general medical condition": 42.458103823346725, "Sputum discoloured": 25.707633823946264, "Sputum purulent": 167.39246541651318, "Stenotrophomonas infection": 263.0032296998307, "Symptom recurrence": 75.6748400105427, "Therapeutic product effect incomplete": 11.954819182696554, "Therapy cessation": 43.81347348211298, "Therapy interrupted": 34.8688141095107, "Total lung capacity increased": 1487.0384993080331, "Type 2 diabetes mellitus": 19.028015269109563, "Upper respiratory tract infection": 5.824487494924433, "Upper-airway cough syndrome": 17.52272997128199, "Ventricular hypokinesia": 94.36227366591687, "Vital capacity decreased": 92.33591239843228, "Weight increased": 4.775470346259801, "Wheezing": 29.27373951055883}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/210.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/210.json
index d8122f380d1..10ec64115ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/210.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/210.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.8355616895806506, "Accident ": 2.315398073472308, "Accidental exposure to product by child ": 17.409660782481858, "Accidental overdose ": 6.53919443231089, "Accidental poisoning ": 54.74420489178731, "Affective disorder ": 3.249911106346879, "Aggression ": 2.165610211180338, "Agitation ": 2.207585711126044, "Agitation neonatal ": 17.284109828083114, "Alcohol abuse ": 25.525510957673585, "Alcohol interaction ": 44.68683468712696, "Alcohol poisoning ": 5.018914508430233, "Amniotic fluid volume decreased ": 24.188356581137707, "Anaemia neonatal ": 19.956743561398472, "Application site burn ": 5.458120222090591, "Application site erythema ": 4.786551077400051, "Application site haemorrhage ": 9.492685819225697, "Application site hypersensitivity ": 15.44300794738935, "Application site inflammation ": 7.765091028739306, "Application site irritation ": 6.1062402543127945, "Application site pruritus ": 8.080385395562752, "Application site rash ": 16.781670821873718, "Application site vesicles ": 4.574628984404338, "Arteriosclerosis coronary artery ": 3.374393736114491, "Asphyxia ": 12.84766290781818, "Aspiration ": 7.280313542139817, "Attention deficit hyperactivity disorder ": 3.0347779519353497, "Back injury ": 14.304654506604487, "Behavioural addiction ": 96.24331586754238, "Blood disorder ": 4.677106849785689, "Bradycardia foetal ": 7.361215404242665, "Bradyphrenia ": 2.197732525837472, "Bradypnoea ": 10.589530073797471, "Brain injury ": 7.700207391473283, "Brain oedema ": 6.383212401596551, "Breakthrough pain ": 19.029211966542384, "Cachexia ": 2.584821650709686, "Cardio-respiratory arrest ": 3.434011060900461, "Central nervous system lesion ": 2.806281438604188, "Central sleep apnoea syndrome ": 14.586589716761187, "Cerebrovascular disorder ": 4.797888877720484, "Choking ": 9.086827072912566, "Cleft palate ": 6.464701926509824, "Cluster headache ": 7.783578870952571, "Cognitive disorder ": 5.050487804365362, "Coma ": 3.020476739536321, "Coma scale abnormal ": 4.122501826544385, "Communication disorder ": 3.1971127140870004, "Compartment syndrome ": 4.805018719094041, "Congenital anomaly ": 4.119362281984643, "Constipation ": 2.566940049199054, "Convulsive threshold lowered ": 28.39325056500068, "Death ": 2.657805406220246, "Defaecation urgency ": 3.314984310491812, "Delirium ": 2.0216086755866853, "Dental caries ": 2.4035610381431987, "Dependence ": 79.08272387997405, "Depressed level of consciousness ": 3.764046151100724, "Depression ": 2.8313104439772623, "Dermal cyst ": 12.284136550451947, "Dermatitis contact ": 2.07891284937889, "Developmental delay ": 14.514236001682152, "Disorientation ": 2.149674896076566, "Drowning ": 11.926260110277816, "Drug abuse ": 21.72410629812369, "Drug abuser ": 19.704887253230016, "Drug delivery system removal ": 68.49806078669826, "Drug dependence ": 86.15548549958771, "Drug detoxification ": 62.7676433318373, "Drug diversion ": 28.714541858225896, "Drug effect less than expected ": 5.539856056226332, "Drug interaction ": 2.7661481870268805, "Drug screen positive ": 67.45730433557031, "Drug tolerance ": 13.567579325375942, "Drug use disorder ": 37.26606121857372, "Drug withdrawal syndrome ": 27.842789035770043, "Drug withdrawal syndrome neonatal ": 97.08059788737272, "Dysarthria ": 2.549257259709028, "Endocarditis ": 7.656599213260483, "Energy increased ": 6.498482766159041, "Euphoric mood ": 6.210743722049658, "Exposure during pregnancy ": 3.1662705663722224, "Exposure via breast milk ": 39.10463075996768, "Foetal distress syndrome ": 6.325865420498625, "Foetal exposure during pregnancy ": 15.56832516209769, "Foetal growth restriction ": 4.1397101691468645, "Gastrointestinal motility disorder ": 3.94302250719799, "Gingival recession ": 9.233411682564128, "Hallucination ": 2.484367839538232, "Hallucination, auditory ": 2.493256477463464, "Hallucination, visual ": 2.118331411614356, "Hepatitis C ": 2.616354011731244, "Homicidal ideation ": 2.1238575846109318, "Hormone level abnormal ": 3.020590107473531, "Hospitalisation ": 2.113605751746064, "Hypercapnia ": 2.860313541766849, "Hypertonia ": 2.3953211018168417, "Hypoglycaemic coma ": 3.259739869796056, "Impaired driving ability ": 8.362032667384627, "Impaired quality of life ": 4.118207776924648, "Impetigo ": 6.127622959244162, "Inadequate analgesia ": 22.19814327820291, "Incoherent ": 6.051110483875157, "Infantile spitting up ": 27.81106275828233, "Infertility ": 7.959547325910669, "Inflammatory pain ": 13.26306618132073, "Intentional product misuse ": 9.582081594534106, "Intentional product use issue ": 3.898457835824432, "Intentional self-injury ": 2.683340069917237, "Intentional underdose ": 33.65582974033644, "Intervertebral disc degeneration ": 2.662849265182701, "Jaundice neonatal ": 21.893004660003403, "Lactation insufficiency ": 4.050284222857967, "Learning disability ": 91.58770942141544, "Logorrhoea ": 6.108321229144807, "Loss of employment ": 4.588916946451849, "Low birth weight baby ": 20.25032575669563, "Mastication disorder ": 5.774222572980701, "Maternal exposure during pregnancy ": 6.134404078914449, "Meconium aspiration syndrome ": 55.65212136844276, "Mental disorder ": 3.599401039950524, "Miosis ": 20.801779228987996, "Morning sickness ": 18.22255925453364, "Multiple injuries ": 2.907422192268827, "Mydriasis ": 2.404934533720903, "Myelopathy ": 6.326400490750471, "Neonatal respiratory distress ": 14.094190526716243, "Neonatal respiratory distress syndrome ": 3.092174419768444, "Nephrosclerosis ": 16.353003377355375, "Neurosis ": 10.273899666770747, "Oesophagitis ": 3.557041080146793, "Oral administration complication ": 42.92551807710531, "Overdose ": 14.254464251949674, "Palmoplantar pustulosis ": 16.099570661677454, "Pancreatitis chronic ": 4.602314932703579, "Panic disorder ": 4.889299511850244, "Paranoia ": 2.952757758044624, "Parasomnia ": 31.775020412595183, "Peripheral ischaemia ": 2.1026600225188123, "Persecutory delusion ": 4.591784747475368, "Persistent depressive disorder ": 13.716209978852586, "Personal relationship issue ": 48.42419137200845, "Piloerection ": 6.007709716303477, "Placenta praevia ": 18.21596402642002, "Placental disorder ": 19.89339561215432, "Placental hypertrophy ": 529.6759586755849, "Plantar fasciitis ": 7.228054978638736, "Poisoning ": 6.882243667861207, "Poor feeding infant ": 20.123467965601407, "Post-traumatic stress disorder ": 10.88150043884504, "Potentiating drug interaction ": 2.1222690807636777, "Pre-eclampsia ": 6.531750250919719, "Premature baby ": 9.725551105522197, "Premature delivery ": 14.039920316491598, "Premature labour ": 3.0328779567838144, "Premature rupture of membranes ": 7.456442850774994, "Premature separation of placenta ": 5.754082094937249, "Prescribed overdose ": 2.335282693055624, "Prescription drug used without a prescription ": 8.015065640435287, "Procedural pain ": 2.166426081191697, "Product adhesion issue ": 14.719613437850914, "Product preparation issue ": 52.12205912713963, "Product prescribing issue ": 4.788986931744423, "Product quality issue ": 2.213004071972424, "Psychomotor skills impaired ": 2.2454057652861805, "Psychotic behaviour ": 8.004819329406565, "Psychotic disorder ": 2.1640287058647862, "Pulmonary congestion ": 4.379786577794716, "Pulmonary oedema ": 3.3249581535122426, "Pulse absent ": 2.7437927120993386, "Quadriparesis ": 9.843175232473977, "Respiratory acidosis ": 3.0958540336687204, "Respiratory arrest ": 4.297963865726016, "Respiratory depression ": 14.354534020794986, "Respiratory disorder neonatal ": 14.351174185680282, "Respiratory rate decreased ": 5.974765783079768, "Rib fracture ": 2.6467355133248778, "Road traffic accident ": 4.476398343965341, "Sarcopenia ": 30.476718574151896, "Schizophrenia ": 3.2067626358179955, "Sciatica ": 2.171464614485522, "Seborrhoeic dermatitis ": 5.307505567934524, "Secondary hypogonadism ": 45.783319740548585, "Sedation ": 5.074305626637121, "Selective eating disorder ": 5.307505567934524, "Self-destructive behaviour ": 5.285419918779858, "Serotonin syndrome ": 3.970031472505516, "Skin abrasion ": 2.6337676566742574, "Skin irritation ": 4.579212984235571, "Small for dates baby ": 5.180718896981786, "Social anxiety disorder ": 15.279515369689966, "Somnambulism ": 35.9118997521194, "Somnolence ": 2.2048592885403626, "Spinal osteoarthritis ": 3.0141828150622616, "Spinal stenosis ": 3.0566813428185005, "Stillbirth ": 4.073437245769126, "Stress cardiomyopathy ": 2.489382802336752, "Substance abuse ": 49.51614315149234, "Substance dependence ": 5.169138856838602, "Substance use ": 16.87081871335275, "Substance use disorder ": 159.01471099110535, "Substance-induced psychotic disorder ": 14.284913224900988, "Suicidal ideation ": 2.9902942532345143, "Suicide attempt ": 2.729006637667482, "Suspected suicide ": 3.902483120308784, "Therapeutic response delayed ": 10.908461571499792, "Therapy interrupted ": 2.5815328629074745, "Thermal burn ": 29.20837035941515, "Tooth disorder ": 2.271922816643417, "Toxicity to various agents ": 9.790995253756844, "Tremor neonatal ": 56.35963320296602, "Type IIa hyperlipidaemia ": 53.46692491119072, "Umbilical cord around neck ": 15.315674338477075, "Unresponsive to stimuli ": 3.654478409210671, "Vitamin B12 deficiency ": 6.258006334091199, "Withdrawal syndrome ": 12.966031460338863, "Wrong technique in product usage process ": 2.941218171317923, "Yawning ": 9.91141519496481}
\ No newline at end of file
+{"Drug ineffective": 3.920518491394776, "Epilepsy": 15.45352692017746, "Off label use": 2.345435666673895, "Product use issue": 10.439739296252949, "Respiratory arrest": 27.030711394120697, "Respiratory depression": 166.99216145940065, "Seizure": 8.830190735335172, "Somnolence": 5.271425647384082, "Status epilepticus": 66.22376736825215}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/211.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/211.json
index 5883858326a..2c8f1c1600d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/211.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/211.json
@@ -1 +1 @@
-{"Acute graft versus host disease ": 81.29891484665166, "Acute graft versus host disease in skin ": 118.4034805952871, "Acute lymphocytic leukaemia ": 57.448449464922845, "Acute lymphocytic leukaemia recurrent ": 56.284012797622, "Acute myeloid leukaemia ": 19.24598785197774, "Acute respiratory distress syndrome ": 14.320446438032931, "Adenovirus infection ": 48.6658719199235, "Bacterial sepsis ": 83.33242876119397, "Blood culture positive ": 103.77352728849492, "Bone marrow failure ": 38.27667475952431, "Bone marrow leukaemic cell infiltration ": 2456.0126545508742, "Bronchopulmonary aspergillosis ": 26.42179859007554, "Cardiac failure ": 3.039116890426894, "Cardiogenic shock ": 15.663790544067131, "Chronic graft versus host disease ": 92.25667860801164, "Cystitis haemorrhagic ": 97.63855129890494, "Cytomegalovirus infection ": 194.71393876786763, "Cytomegalovirus infection reactivation ": 27.77254114733388, "Dermatitis bullous ": 12.529835505686144, "Disease recurrence ": 14.74881943694129, "Ejection fraction decreased ": 16.800757351779417, "Encephalopathy ": 7.479959172991069, "Engraftment syndrome ": 413.5642157944732, "Epstein-Barr virus infection ": 98.65928912553773, "Epstein-Barr virus infection reactivation ": 168.89007609724024, "Febrile bone marrow aplasia ": 74.02413595356012, "Febrile neutropenia ": 11.183740004502177, "Gamma-glutamyltransferase increased ": 3.423438738546759, "Graft versus host disease ": 23.23780984134875, "Haematuria ": 4.311988840851732, "Hepatic cytolysis ": 18.580576274601707, "Hepatitis acute ": 14.783695190770024, "Hepatosplenomegaly ": 56.23841639202787, "Infection ": 2.909542338639981, "Leukaemia recurrent ": 121.42520941204472, "Lung disorder ": 5.911660749875731, "Mucosal inflammation ": 48.793652386192434, "Multiple organ dysfunction syndrome ": 7.743620550804389, "Myocarditis ": 8.446375965893624, "Neurotoxicity ": 12.943401651148482, "Pericarditis ": 3.152704432560703, "Platelet count increased ": 17.440617916739587, "Post transplant lymphoproliferative disorder ": 71.99214415824973, "Pseudomonal sepsis ": 174.78341325570173, "Rash maculo-papular ": 2.386765216578421, "Respiratory failure ": 2.8659695464173565, "Sepsis ": 8.610528958386942, "Septic shock ": 21.38006151640097, "Serratia sepsis ": 2701.909723011382, "Staphylococcal infection ": 8.324231707801951, "Stomatitis ": 14.75385260905805, "Thrombotic microangiopathy ": 42.7143209847935, "Venoocclusive disease ": 754.830182378999, "Venoocclusive liver disease ": 271.66230054057127}
\ No newline at end of file
+{"Abdominal pain": 2.7300094367081367, "Acquired factor V deficiency": 117.82554711672606, "Acute graft versus host disease": 10.933763298807744, "Adenovirus infection": 14.144251510988653, "Adrenal insufficiency": 6.68986071186321, "Adrenal suppression": 19.057600962222093, "Adrenocortical insufficiency acute": 12.034971753495077, "Adverse drug reaction": 4.84343170454478, "Alcoholism": 4.009889248131433, "Alternaria infection": 116.0331301026762, "Anaemia": 3.159064299631398, "Anal fissure": 2.206003130292276, "Angiopathy": 4.8402087400015725, "Arthropod bite": 2.547574073810134, "Aspergillus infection": 6.0440470551298615, "Asphyxia": 3.017685138202077, "Aspiration": 16.005811164473187, "Asthma": 15.275400873416944, "Asthmatic crisis": 5.275316004564502, "BK virus infection": 10.199630697849, "Blood calcium increased": 20.54637399970606, "Blood corticotrophin decreased": 13.213170241211804, "Blood immunoglobulin E increased": 58.37412390584598, "Blood lactic acid increased": 30.414420167968856, "Blood potassium decreased": 11.535205599183673, "Blood test abnormal": 13.252594626829008, "Body height decreased": 2.179231760351313, "Botulism": 41.012281781362304, "Bradyarrhythmia": 2.037896077226587, "Brain herniation": 2.1810019241330987, "Breath sounds abnormal": 37.49314113453619, "Bronchial hyperreactivity": 3.242763346309713, "Bronchial secretion retention": 11.928218076687228, "Bronchiectasis": 20.217278246542453, "Bronchitis": 2.240629338108952, "Bronchitis bacterial": 23.34454584816237, "Bronchopulmonary aspergillosis": 2.844801888297724, "Bronchopulmonary aspergillosis allergic": 153.3986031525177, "Butterfly rash": 17.709138302833093, "Cardiac valve disease": 2.5821559195074437, "Central obesity": 5.220533402869922, "Chest X-ray abnormal": 50.12963326981951, "Chest discomfort": 4.059843228022255, "Cholangitis sclerosing": 4.214940697976088, "Chronic obstructive pulmonary disease": 3.0152899880774853, "Chronic sinusitis": 112.4732928564592, "Chronic spontaneous urticaria": 4.566296981391711, "Coagulation factor V level abnormal": 90.7318913725346, "Coagulation factor deficiency": 54.20292999250894, "Colitis": 19.979694483487616, "Colitis microscopic": 7.959958764685112, "Colitis ulcerative": 21.62515829078506, "Computerised tomogram abnormal": 2.108496394900021, "Conduction disorder": 2.7108395083934798, "Congenital anomaly": 2.2528147131974734, "Constipation": 5.416659099174656, "Cortisol decreased": 11.55515201522584, "Cough": 3.283550024049412, "Crohn's disease": 4.222573643400962, "Cryptococcosis": 10.468026461528035, "Cushing's syndrome": 15.406352189259524, "Cushingoid": 7.703342063386803, "Cystitis haemorrhagic": 4.280759508910763, "Cytokine storm": 5.147149514008574, "Cytomegalovirus colitis": 2.8463618035224103, "Cytomegalovirus infection reactivation": 4.35893331297208, "Defaecation urgency": 5.341900864581514, "Diastolic dysfunction": 3.9041260141552767, "Distractibility": 7.606981064112952, "Drug hypersensitivity": 2.79097074765854, "Drug ineffective": 2.2702683691209256, "Dyspepsia": 6.908092441367615, "Dysphonia": 4.342668859194102, "Dyspnoea": 2.407245253201442, "Dyspnoea exertional": 2.1035006709189874, "Ear pruritus": 56.217958225519496, "Ectropion": 52.59503626972936, "Electrocardiogram repolarisation abnormality": 6.125364422174823, "Embolism venous": 5.154034674399293, "Emphysema": 6.312721943956484, "Encephalitis cytomegalovirus": 29.75618383806537, "Eosinophil count decreased": 17.980122558507603, "Eosinophil count increased": 13.465190152228306, "Eosinophilia": 14.715432877872876, "Eosinophilic bronchitis": 119.20021936773516, "Eosinophilic granulomatosis with polyangiitis": 6.105644701946265, "Epstein-Barr viraemia": 13.843757216251833, "Epstein-Barr virus infection reactivation": 2.525381270144168, "Erythema": 2.5678526094827645, "Eye pruritus": 13.378025729940962, "Eyelid disorder": 3.8300227755115928, "Factor V Leiden mutation": 44.0306050819768, "Faecal calprotectin increased": 16.046685109810927, "Female genital tract fistula": 137.9401832500308, "Forced expiratory volume decreased": 4.435310806827292, "Forced vital capacity decreased": 10.341640257267889, "Frequent bowel movements": 40.476029735495786, "Full blood count abnormal": 34.038595651177395, "Gastrointestinal inflammation": 2.2108210901375727, "Gastrointestinal ulcer": 5.326384884646954, "Gastrooesophageal reflux disease": 8.671379160273629, "Graft versus host disease": 2.407666985102093, "Graft versus host disease in gastrointestinal tract": 12.763184582639123, "Graft versus host disease in liver": 10.779260772207216, "Graft versus host disease in skin": 10.1239218380943, "Growth failure": 37.25875595641253, "Growth retardation": 8.20345612096366, "Haematochezia": 13.365498338546534, "Haemoptysis": 4.193687167688098, "Haemothorax": 7.925522750841215, "Head deformity": 15.847504722766072, "Hiatus hernia": 2.2470960450838016, "Human herpesvirus 6 infection": 5.107681489634913, "Hyperglycaemia": 3.63763943376614, "Hypogammaglobulinaemia": 5.498851029827721, "Hyporeflexia": 2.072957071479217, "Hypothalamic pituitary adrenal axis suppression": 16.515169332122458, "Hypovolaemia": 5.965471218526047, "Hypoxia": 3.897339657108935, "Hysterectomy": 3.535368505413264, "Ill-defined disorder": 4.193437401191037, "Impaired quality of life": 3.32650437557122, "Impulsive behaviour": 2.3152326186119097, "Increased anteroposterior chest diameter": 106.06717249639952, "Inflammatory bowel disease": 2.0864242281332905, "Infusion related reaction": 11.4179530028121, "Inhibitory drug interaction": 3.43575326457935, "Inspiratory capacity decreased": 79.46862170332938, "Intentional device misuse": 2.782245902870621, "Judgement impaired": 5.545544177368384, "Lacrimation increased": 10.115190666666445, "Laryngeal stenosis": 509.07756759914537, "Latent tuberculosis": 3.770646804460164, "Liver function test increased": 4.605302830907013, "Loss of personal independence in daily activities": 9.873777551534156, "Lower respiratory tract infection": 4.080977361025123, "Lung diffusion test abnormal": 867.2468798801431, "Lung disorder": 5.616732655022334, "Lung opacity": 24.29828124766906, "Macular degeneration": 56.72307316788549, "Mechanical ventilation complication": 86.33677395707004, "Middle insomnia": 16.57526114968571, "Mite allergy": 2.686086385281484, "Mucous stools": 2.4453969538567577, "Multiple allergies": 12.947290673729622, "Nasal congestion": 6.789568429258964, "Nasal obstruction": 15.036371413982222, "Nasal polyps": 65.23221288024948, "Neutrophilia": 5.575686486845673, "Obstructive airways disorder": 36.59375227361463, "Oesophageal disorder": 2.9712665119686616, "Oligoarthritis": 13.780891405367475, "Oral candidiasis": 40.82296899556298, "Oropharyngeal candidiasis": 4.834444441531706, "Paraesthesia oral": 16.546404386972316, "Periorbital oedema": 2.34994866818574, "Pharyngitis streptococcal": 8.700246272217626, "Platelet count increased": 20.787473086451257, "Pleural effusion": 2.111132981833204, "Pleuritic pain": 24.893644284213497, "Pneumonia viral": 5.515432395073896, "Pneumothorax": 3.868043987615558, "Polyp": 4.777107204901459, "Pouchitis": 22.05702631432785, "Procedural pain": 61.95597092553348, "Proctitis": 109.50216566278873, "Productive cough": 3.074658513988348, "Pseudo Cushing's syndrome": 15.593398400521718, "Pulmonary fibrosis": 6.524570934354902, "Pulmonary function test abnormal": 115.04014530067928, "Pulmonary mass": 8.880624013407303, "Radiculopathy": 91.9818607997044, "Rales": 9.169499734078244, "Rectal haemorrhage": 12.822351893438196, "Respiratory symptom": 4.246787092756077, "Respiratory syncytial virus infection": 5.0553232680204365, "Respiratory tract infection": 2.056813947757735, "Reversible airways obstruction": 37.97060983587777, "Rhinitis allergic": 28.36692963226757, "Rhinorrhoea": 4.815145659535723, "Rhonchi": 5.612586226939975, "Salpingo-oophorectomy unilateral": 142.22034834559776, "Secondary adrenocortical insufficiency": 2.6922832908971093, "Secretion discharge": 2.8561394821655317, "Septic embolus": 6.392921300598834, "Shock haemorrhagic": 2.08767918449413, "Sinonasal obstruction": 9.285437597161811, "Sinus disorder": 28.019351824922225, "Sinus polyp": 87.31958818224396, "Sinusitis": 3.041256847833947, "Sinusitis fungal": 43.89791654029119, "Skin lesion": 6.897497900967289, "Skin striae": 3.006354328425729, "Skin test positive": 6.525128425823015, "Sleep disorder due to a general medical condition": 25.558990202543665, "Sneezing": 11.882511313996368, "Sputum culture positive": 62.32785045277529, "Sputum discoloured": 10.174278711507355, "Sputum increased": 3.247077537924551, "Staphylococcal sepsis": 2.7246974142268883, "Stenotrophomonas infection": 27.490492240107876, "Suspected suicide": 2.9233628309967323, "Synovial cyst": 2.0983367163542326, "Systemic mycosis": 36.288329716460815, "Tachypnoea": 4.01051007526358, "Therapeutic product effect incomplete": 14.466641687330805, "Therapeutic response shortened": 2.1395004511447726, "Throat clearing": 17.442777628617595, "Total lung capacity decreased": 26.147651963816056, "Type 2 diabetes mellitus": 13.391609187452982, "Upper respiratory fungal infection": 202.21759055765017, "Upper-airway cough syndrome": 78.58362343641421, "Use of accessory respiratory muscles": 15.93467343237572, "Vaginal discharge": 62.11813741416628, "Vaginal flatulence": 168.64470450846497, "Vasculitis": 11.918564411257377, "Vena cava filter insertion": 20.99565615678052, "Vital capacity decreased": 36.49460458161921, "Vocal cord dysfunction": 289.5288823974089, "Weight decreased": 3.5594145992663533, "Wheezing": 16.156915227122294}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/212.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/212.json
index 54adf0bc3db..ec5f372f686 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/212.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/212.json
@@ -1 +1 @@
-{"Acidosis hyperchloraemic ": 14.107815542605156, "Acute graft versus host disease ": 193.1440571328875, "Acute graft versus host disease in intestine ": 200.55528389491263, "Acute graft versus host disease in liver ": 182.15539990892736, "Acute graft versus host disease in skin ": 311.7448682611912, "Acute hepatic failure ": 2.780124815509895, "Acute lymphocytic leukaemia ": 10.02491392024542, "Acute myeloid leukaemia ": 10.57452617726285, "Acute myeloid leukaemia recurrent ": 55.16017813971893, "Acute respiratory distress syndrome ": 12.648409319138288, "Adenovirus infection ": 95.57277397423591, "Anal abscess ": 4.576783656522131, "Aplasia pure red cell ": 3.1618252550748163, "Aplastic anaemia ": 25.37713273505147, "Ascites ": 3.594930684798791, "Aspergillus infection ": 23.474763388473686, "Atrial flutter ": 7.240047845761822, "Atrial thrombosis ": 7.890785400445456, "Atrophy ": 9.992748364049136, "Autoimmune haemolytic anaemia ": 14.26162216381147, "BK virus infection ": 147.88251810344386, "Bacteraemia ": 25.7529876452356, "Bacterial infection ": 5.941789298979464, "Bacterial sepsis ": 25.124643237476256, "Blast crisis in myelogenous leukaemia ": 20.97366734128727, "Blood bilirubin increased ": 3.486862881073948, "Blood culture positive ": 27.83480096752594, "Blood follicle stimulating hormone increased ": 190.06893961592425, "Blood lactate dehydrogenase increased ": 3.005814240597992, "Blood luteinising hormone increased ": 295.7777902260594, "Bone marrow failure ": 18.62500982922477, "Bone marrow transplant rejection ": 39.907332911292194, "Bronchiectasis ": 11.1842811433471, "Bronchopulmonary aspergillosis ": 27.417968481722333, "Budd-Chiari syndrome ": 44.935351663465546, "Candida infection ": 6.315696963843496, "Capillary leak syndrome ": 6.670903162944272, "Cardiac failure acute ": 2.0816267485492226, "Cardiac tamponade ": 5.509416723798056, "Cardiotoxicity ": 5.151881238545597, "Central hypothyroidism ": 27.285836494781847, "Central nervous system lesion ": 3.715261734248279, "Cerebral toxoplasmosis ": 70.89546080389519, "Cervical dysplasia ": 6.993450106179345, "Chloroma ": 94.02116822976492, "Chronic graft versus host disease ": 170.66887498562906, "Chronic graft versus host disease in intestine ": 138.414886265655, "Chronic graft versus host disease in liver ": 107.35096369770751, "Chronic graft versus host disease in skin ": 138.67113462874983, "Chronic myeloid leukaemia ": 4.06699021696152, "Clostridium difficile colitis ": 8.38059916654329, "Clostridium difficile infection ": 7.298510760995515, "Congenital aplasia ": 13.573785602251816, "Coombs positive haemolytic anaemia ": 22.04517632426809, "Cystitis haemorrhagic ": 217.53504642696905, "Cystitis viral ": 115.02302626300973, "Cytokine release syndrome ": 2.2463588051073278, "Cytomegalovirus chorioretinitis ": 61.42438269606701, "Cytomegalovirus colitis ": 8.628847777560736, "Cytomegalovirus infection ": 63.95201148293373, "Cytomegalovirus infection reactivation ": 159.62287621601405, "Cytomegalovirus test positive ": 59.35296027131064, "Cytomegalovirus urinary tract infection ": 1227.9181626583058, "Cytomegalovirus viraemia ": 146.91842158669846, "Cytopenia ": 5.670162834400365, "Delayed puberty ": 129.02125984041857, "Device related infection ": 8.281061265787423, "Diarrhoea haemorrhagic ": 2.072825104284488, "Diffuse alveolar damage ": 32.70588557987999, "Diffuse large B-cell lymphoma ": 6.482789056245867, "Disease recurrence ": 2.807656527548968, "Disseminated intravascular coagulation ": 3.4204300779796397, "Disseminated mucormycosis ": 54.0088220720664, "Disseminated toxoplasmosis ": 701.8897742239742, "Drug ineffective for unapproved indication ": 3.3457941497068537, "Drug resistance ": 2.1420656482557527, "Dysbiosis ": 43.407374055249264, "Encephalitis ": 6.163553681846095, "Encephalitis autoimmune ": 6.772221501973049, "Encephalitis cytomegalovirus ": 52.12467669229815, "Encephalitis viral ": 19.644959725749363, "Engraft failure ": 108.7220419288741, "Engraftment syndrome ": 186.87934963169707, "Enterobacter sepsis ": 92.0940402289468, "Enterococcal bacteraemia ": 60.51529564307113, "Enterococcal infection ": 23.388969039942488, "Enterocolitis ": 2.444250509017356, "Epstein-Barr viraemia ": 153.67527001838934, "Epstein-Barr virus associated lymphoproliferative disorder ": 22.55157131804581, "Epstein-Barr virus infection ": 47.91243412020574, "Epstein-Barr virus infection reactivation ": 99.74191006602288, "Escherichia infection ": 11.530374197714682, "Escherichia sepsis ": 16.549893273035448, "Febrile neutropenia ": 18.71947842270012, "Focal dyscognitive seizures ": 7.644417728075359, "Fungaemia ": 30.66480484081361, "Fungal infection ": 6.104814002210159, "Fusarium infection ": 35.023976255237145, "Gastroenteritis norovirus ": 23.718490400702525, "Gastrointestinal infection ": 23.412423763860627, "Gastrointestinal toxicity ": 5.18593778131551, "Glomerulonephritis membranous ": 25.566605341903905, "Glycosuria ": 7.056713035265832, "Graft versus host disease ": 138.00101125312173, "Graft versus host disease in gastrointestinal tract ": 86.22048577833976, "Graft versus host disease in liver ": 44.62080980683538, "Graft versus host disease in lung ": 106.16440527464154, "Graft versus host disease in skin ": 139.3816112027737, "Granulocytopenia ": 4.39736253958738, "Guillain-Barre syndrome ": 2.506890657431361, "Haematuria ": 3.247005184692256, "Haemophagocytic lymphohistiocytosis ": 12.735978819569176, "Haemorrhage intracranial ": 2.719897178621857, "Hepatic failure ": 3.617915090601779, "Hepatic necrosis ": 9.069035468308886, "Hepatitis B reactivation ": 5.724345535841566, "Hepatomegaly ": 6.599491125356257, "Hepatorenal syndrome ": 8.959935614720834, "Hepatotoxicity ": 2.431575437933876, "Herpes simplex ": 15.249599885558348, "Herpes virus infection ": 2.6719051513592813, "Hodgkin's disease recurrent ": 39.907332911292194, "Human herpesvirus 6 encephalitis ": 118.49804674405908, "Human herpesvirus 6 infection ": 62.01914261454116, "Human polyomavirus infection ": 66.82798057863587, "Hyperammonaemia ": 2.090967040869951, "Hyperbilirubinaemia ": 3.87806983093957, "Hyperlipidaemia ": 2.853827667827028, "Hypouricaemia ": 40.73581760421237, "Idiopathic pneumonia syndrome ": 163.27742089422068, "Infection ": 3.872066821518728, "Infection reactivation ": 55.12921392895281, "Intervertebral disc protrusion ": 3.254940609237684, "JC virus infection ": 40.178881316155525, "Kaposi's sarcoma ": 14.889126175579989, "Keratitis ": 5.713810577548849, "Klebsiella infection ": 36.0755318906041, "Klebsiella sepsis ": 17.184254697535707, "Laryngitis fungal ": 102.8057420411659, "Left ventricular failure ": 5.956514453682168, "Leukaemia ": 3.096675511503505, "Leukaemia recurrent ": 70.90840328640249, "Leukoencephalopathy ": 6.555732155237148, "Lower respiratory tract infection fungal ": 48.61019454980439, "Lung disorder ": 2.368149783602854, "Lung opacity ": 4.047817045541906, "Lymphopenia ": 2.9730582623370165, "Lymphoproliferative disorder ": 17.796190320270146, "Marrow hyperplasia ": 17.4808144502965, "Meningitis tuberculous ": 22.12015713521552, "Metapneumovirus infection ": 30.61399722634533, "Metastasis ": 5.177259549220746, "Microangiopathy ": 15.405417284640798, "Mouth ulceration ": 3.9299150183359046, "Mucormycosis ": 44.88734426588955, "Mucosal disorder ": 4.335723610741874, "Mucosal inflammation ": 47.55871649349039, "Multiple organ dysfunction syndrome ": 10.286826091907466, "Myelitis transverse ": 4.226140079003772, "Myelodysplastic syndrome ": 7.161471491029698, "Myelofibrosis ": 6.329638474031602, "Myelosuppression ": 3.445198919691956, "Nephropathy toxic ": 3.2751340617532256, "Neurotoxicity ": 6.265438266096305, "Neutropenia ": 2.090190738439025, "Neutropenic colitis ": 16.35751232270599, "Nocardiosis ": 12.417675481283103, "Obliterative bronchiolitis ": 29.54317595540411, "Oedematous pancreatitis ": 24.938014720560727, "Off label use ": 4.25323962880498, "Organ failure ": 10.21027844138946, "Organising pneumonia ": 2.603624781525339, "Ovarian atrophy ": 1022.0490136637568, "Ovarian failure ": 265.69886583984, "Pancreatitis haemorrhagic ": 35.44391106075367, "Pancytopenia ": 9.019469751530236, "Pathogen resistance ": 3.803979014492161, "Pericardial effusion ": 5.195245376335139, "Pleural effusion ": 2.5422128560813952, "Pneumatosis intestinalis ": 7.57745351509045, "Pneumocystis jirovecii pneumonia ": 8.031047056597318, "Pneumonia ": 2.106035617248795, "Pneumonia bacterial ": 4.195578829682562, "Pneumonia cytomegaloviral ": 48.776310994085286, "Pneumonia fungal ": 23.135992557986835, "Pneumonia klebsiella ": 21.14592111819901, "Pneumonitis ": 4.553334006101009, "Pneumothorax ": 2.3874695951704363, "Polyomavirus viraemia ": 241.51640210653483, "Post transplant lymphoproliferative disorder ": 51.63142090930607, "Posterior reversible encephalopathy syndrome ": 19.12680278572686, "Premature menopause ": 114.60410294816032, "Primary hypogonadism ": 400.9560442398337, "Product administered to patient of inappropriate age ": 11.65685254376015, "Product use in unapproved indication ": 9.461775269568596, "Progressive multifocal leukoencephalopathy ": 16.87596785205346, "Pseudomonal sepsis ": 13.548186059616684, "Pseudomonas infection ": 6.907619324354034, "Pulmonary alveolar haemorrhage ": 10.708045178031195, "Pulmonary arterial hypertension ": 4.648918764940071, "Pulmonary haemorrhage ": 10.549305345227154, "Pulmonary hypertension ": 6.157160189285119, "Pulmonary toxicity ": 2.6548958598537378, "Pulmonary veno-occlusive disease ": 113.54709767033808, "Recurrent cancer ": 12.887386691288976, "Renal tubular injury ": 49.40772620954456, "Respiratory disorder ": 2.18439540244822, "Respiratory distress ": 2.2399693591287235, "Respiratory failure ": 6.7779388582490245, "Respiratory syncytial virus infection ": 3.96868516111113, "Respiratory tract infection fungal ": 41.77716462776085, "Retinitis viral ": 479.3895253684181, "Retinopathy haemorrhagic ": 209.98767731643892, "Rhinovirus infection ": 17.005345014307576, "Right ventricular failure ": 4.986543555337947, "Second primary malignancy ": 5.633053036629699, "Sepsis ": 7.653170908254111, "Septic shock ": 8.000990570657361, "Shock haemorrhagic ": 3.6374516851319503, "Skin hyperpigmentation ": 2.7998063634887425, "Skin toxicity ": 14.14410952124942, "Spinal stenosis ": 6.296922416291861, "Splenomegaly ": 2.0479511522766205, "Staphylococcal bacteraemia ": 13.39856314880448, "Staphylococcal infection ": 6.017526315367524, "Staphylococcal sepsis ": 13.735725712470389, "Stenotrophomonas infection ": 11.479898729220585, "Stomatitis ": 7.1454754010075545, "Streptococcal bacteraemia ": 97.51845121984452, "Systemic candida ": 11.372327522008648, "Systemic inflammatory response syndrome ": 4.754218232193952, "T-lymphocyte count decreased ": 34.37570549720736, "Testicular atrophy ": 56.37602115457624, "Therapy non-responder ": 2.042154624941661, "Thrombocytopenia ": 3.671840911183093, "Thrombotic microangiopathy ": 59.23649296479554, "Thrombotic thrombocytopenic purpura ": 9.798962658381337, "Toxic encephalopathy ": 3.9563340857626166, "Toxoplasmosis ": 62.79826536846847, "Transplant failure ": 135.55401003759306, "Transplant rejection ": 19.32369913481561, "Traumatic lung injury ": 12.417675481283103, "Tubulointerstitial nephritis ": 3.4627656282054597, "Urinary tract obstruction ": 15.6178632561089, "Vanishing bile duct syndrome ": 45.24553595218547, "Varicella zoster virus infection ": 20.3689079644511, "Venoocclusive disease ": 300.2737355872748, "Venoocclusive liver disease ": 300.06852248616127, "Viral haemorrhagic cystitis ": 247.341756697426, "Viral infection ": 5.560984792106985}
\ No newline at end of file
+{"Abnormal behaviour": 6.596792511968096, "Acute kidney injury": 13.430267475823124, "Aggression": 4.057387510271644, "Amnesia": 3.889045767515914, "Anxiety disorder": 42.010011533516206, "Arteriosclerosis coronary artery": 45.42836115240488, "Atrial fibrillation": 6.616797888095315, "Blood cholesterol increased": 2.059448774912401, "Blood creatinine increased": 7.811397544718428, "Blood potassium increased": 4.28868497506558, "Blood pressure systolic decreased": 20.205542814212677, "Blood sodium decreased": 4.240698395150697, "Blood urea increased": 3.896770444755978, "Cardiac failure": 9.03978098121913, "Cardiac failure acute": 48.36291223594856, "Cardiac failure chronic": 73.11199206741138, "Cardiac failure congestive": 6.700079931579234, "Cardiomegaly": 27.86399905350964, "Completed suicide": 8.070966578345233, "Coronary artery disease": 4.215655511604572, "Deafness": 3.171814098222176, "Dehydration": 5.133661233773102, "Dermatitis bullous": 4.744126625006627, "Device malfunction": 11.105642019747, "Device occlusion": 41.90979623314222, "Drug dependence": 2.483385532904476, "Drug withdrawal syndrome": 5.3303540269639145, "Eating disorder": 11.562453375194776, "Ejection fraction abnormal": 37.77797055980027, "Ejection fraction decreased": 7.202621769364409, "End stage renal disease": 33.036327395440416, "Faeces discoloured": 22.72127019674856, "Fluid retention": 5.860197558167768, "Gait inability": 5.126562271467251, "Gastrointestinal angiodysplasia": 693.0067012441299, "Gastrointestinal haemorrhage": 5.442925584424548, "Generalised oedema": 6.6065137159538185, "Glomerular filtration rate decreased": 5.943983092291953, "Gout": 5.032878512166839, "Helicobacter infection": 3.866311578004487, "Hospitalisation": 2.973341954330259, "Hyperkalaemia": 14.937726604123108, "Hypernatraemia": 19.02080233809311, "Hypervolaemia": 9.80238224509852, "Hypokalaemia": 6.936315030390356, "Hypokinesia": 5.565785141340589, "Hypomagnesaemia": 21.3094339833183, "Hyponatraemia": 4.37472754916349, "Hypotension": 3.884123838040954, "Hypovolaemia": 61.97871648184076, "Impaired driving ability": 29.19821471069218, "Incarcerated hernia": 1443.7830846389747, "Incorrect dose administered": 3.149264068794942, "International normalised ratio increased": 8.493334721022391, "Interstitial lung disease": 3.851261225899821, "Iron deficiency anaemia": 9.450332269215345, "Left atrial dilatation": 462.6818693399988, "Left ventricular dilatation": 312.61300321709945, "Lethargy": 3.227079935636893, "Lumbar spinal stenosis": 111.1047198134594, "Lung hyperinflation": 424.4136683948769, "Meningitis": 24.377082120436363, "Mitral valve incompetence": 42.96962464155932, "Multiple organ dysfunction syndrome": 3.3194734821854173, "Oedema peripheral": 4.564828847720511, "Orthostatic hypotension": 6.817794498221135, "Overdose": 6.872812829955204, "Pneumonia": 2.256293411654253, "Product administration error": 2.331426833016173, "Psychotic behaviour": 171.91699021283188, "Psychotic disorder": 5.855314795899114, "Pulmonary congestion": 30.546038460782796, "Pulmonary hypertension": 3.4243357696157606, "Renal impairment": 5.614002666269199, "Right atrial dilatation": 556.5390627621568, "Speech disorder": 4.223316646849057, "Spinal cord abscess": 1024.6447354191264, "Substance abuse": 10.415776977316725, "Toxicity to various agents": 9.163239687410714, "Urine output decreased": 7.375202630350306, "Ventricular tachycardia": 7.952151309760993}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/213.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/213.json
index ce9c21ccf1d..8a0b04c3c4f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/213.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/213.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 11.042530920582866, "Alcohol poisoning ": 65.59706160161677, "Drug dependence ": 4.887444626431577, "Drug titration error ": 1356.4727640371566, "Drug withdrawal syndrome ": 9.062927083250036, "Drug withdrawal syndrome neonatal ": 71.03492023019396, "Exposure via breast milk ": 41.70322730908055, "Foetal exposure during pregnancy ": 6.855405136629372, "Gestational diabetes ": 63.6846969407586, "Hyperhidrosis ": 2.217549279028442, "Injection site abscess ": 90.3706894690186, "Injection site erythema ": 11.58112562317231, "Injection site induration ": 14.16411226087345, "Injection site inflammation ": 2.3447024669156016, "Injection site mass ": 132.48201321544602, "Injection site nodule ": 101.10611988042058, "Injection site pain ": 5.816680215162662, "Injection site pruritus ": 16.98901595649729, "Injection site rash ": 17.38515844174335, "Injection site reaction ": 3.042190760083189, "Injection site swelling ": 8.387197302836425, "Injection site warmth ": 2.733437071209195, "Jaundice neonatal ": 200.11772087021816, "Maternal exposure during pregnancy ": 13.16100771631348, "Oedema peripheral ": 2.725482452977497, "Overdose ": 2.4082585554776474, "Poor feeding infant ": 160.53676347776343, "Premature baby ": 5.547184045710002, "Respiratory depression ": 12.637224958243204, "Toxicity to various agents ": 5.651454062519102, "Urinary retention ": 6.081981140639653, "Withdrawal syndrome ": 60.19141039914823, "Yawning ": 74.95806986209539}
\ No newline at end of file
+{"Abnormal behaviour": 3.058253986678419, "Abnormal loss of weight": 7.007363655143908, "Adverse drug reaction": 3.1648886767878404, "Anaesthetic complication": 23.08295884347801, "Anal incontinence": 8.942581474406607, "Anterior spinal artery syndrome": 886.3754920505269, "Apnoea": 8.641401786173748, "Arachnoiditis": 122.62714978821008, "Areflexia": 21.263933734614277, "Arteriospasm coronary": 7.462088978442651, "Back pain": 3.995412942606041, "Benign prostatic hyperplasia": 7.873169885119372, "Blood pressure decreased": 3.939515681482246, "Bradycardia": 5.347695545726268, "Bradycardia foetal": 44.36661248362168, "Brain herniation": 11.880294347755784, "Burning sensation": 2.494394868292706, "Cardiac arrest": 4.185911641120245, "Cauda equina syndrome": 182.06240414838769, "Cerebrospinal fluid leakage": 27.71586566220831, "Complex regional pain syndrome": 19.02360718915157, "Complication associated with device": 8.585489273048141, "Constipation": 2.2069777058829283, "Coordination 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exposure during delivery": 120.45978787072332, "Foetal exposure during pregnancy": 6.072165798039262, "Foetal growth restriction": 15.962888098324468, "Formication": 3.842590564027162, "Gait inability": 3.012404799069607, "Generalised tonic-clonic seizure": 2.411594132259743, "Haemodynamic instability": 6.405113741447217, "Heart rate decreased": 2.054904534331672, "Horner's syndrome": 42.94025635460892, "Hospitalisation": 2.588873938442315, "Hyperaesthesia": 7.907544864867567, "Hypoacusis": 3.1589771789243724, "Hypoaesthesia": 2.607782365465037, "Hypopnoea": 9.754796598050056, "Hypotension": 3.3450901444343706, "Hypothermia": 2.9087501930525743, "Hypoxia": 3.678711618082422, "Implant site discharge": 264.4196866497728, "Implant site extravasation": 66.2278197104629, "Implant site infection": 49.869817228685655, "Implant site pain": 158.36213007900008, "Incorrect route of product administration": 8.871800324173195, "Infusion site mass": 273.91631586866765, "Intervertebral disc 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"Muscle rigidity": 2.2003652558753712, "Muscle spasms": 3.8022462734058498, "Muscle spasticity": 27.10952948136722, "Muscle tightness": 3.435916019590448, "Muscular weakness": 2.1264301157583283, "Musculoskeletal chest pain": 2.111480637644021, "Myoclonus": 7.249311801855821, "Neonatal respiratory distress syndrome": 9.994869599195711, "Neuralgia": 6.504316006591663, "Neurotoxicity": 4.581303076470617, "No adverse event": 13.154965287089766, "Off label use": 3.222508363058925, "Ophthalmoplegia": 89.2766103320988, "Overdose": 3.840002093198773, "Oxygen saturation decreased": 2.3645950727477967, "Pain": 2.5475517154841048, "Paralysis": 6.695078980430599, "Paraplegia": 25.21998376830586, "Performance status decreased": 45.96755714823983, "Postoperative wound infection": 9.391780331867553, "Postpartum haemorrhage": 41.71038607704833, "Pre-eclampsia": 7.208650426649845, "Premature baby": 14.970023769614745, "Premature delivery": 17.039840627280874, "Prescribed overdose": 6.722360960423224, "Procedural pain": 3.299003172759335, "Product administered to patient of inappropriate age": 12.842102940388692, "Pulseless electrical activity": 13.449411807082342, "Rales": 9.965619968069872, "Respiratory acidosis": 7.120707709980858, "Respiratory arrest": 3.5617465211596944, "Respiratory depression": 15.270348013377712, "Rhythm idioventricular": 227.08604670742065, "Scab": 3.517931451039673, "Sedation": 4.9085230381071945, "Sedation complication": 7.030392944053296, "Sensory disturbance": 2.04410626565695, "Sensory loss": 7.997194100663448, "Sleep apnoea syndrome": 3.3874571243987703, "Spinal compression fracture": 17.5772029753566, "Spinal cord compression": 10.346034734851498, "Spinal cord injury": 83.63878910292564, "Spinal pain": 3.985250368065417, "Spinal stenosis": 12.822836689269012, "Strabismus": 72.01150746244191, "Symmetrical drug-related intertriginous and flexural exanthema": 71.43084091054347, "Therapeutic response decreased": 9.22917049411167, "Therapy non-responder": 12.396732524453135, "Underdose": 3.3745516270611597, "Unevaluable event": 8.38562532101919, "Unresponsive to stimuli": 8.087414028348016, "Urinary incontinence": 2.994035161405056, "Urinary retention": 6.602756607819134, "Uterine hypotonus": 244.1697748862151, "Ventricular arrhythmia": 12.484878862383413, "Ventricular extrasystoles": 2.4640794259256564, "Ventricular tachycardia": 3.8902757405657904, "Withdrawal syndrome": 6.499582205780106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/214.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/214.json
index 52e6423e4db..aa13333356f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/214.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/214.json
@@ -1 +1 @@
-{"Adenocarcinoma pancreas ": 41.74260263019695, "Amylase increased ": 3.8195740959409608, "Atelectasis ": 4.164024426438449, "Basal cell carcinoma ": 2.477330726259868, "Benign prostatic hyperplasia ": 4.465037362524358, "Blood cholesterol abnormal ": 5.854940637230367, "Blood glucose abnormal ": 7.297975957081946, "Blood glucose decreased ": 8.964189560419271, "Blood glucose fluctuation ": 8.447441990114704, "Blood glucose increased ": 8.725857667282526, "Blood pressure abnormal ": 2.190424629530429, "Blood triglycerides increased ": 3.946205933609871, "Body height decreased ": 15.00285044536366, "Breast cancer female ": 6.364684333324517, "Carotid artery occlusion ": 4.771356287771768, "Carpal tunnel syndrome ": 3.856835323588883, "Cataract ": 4.15670668816539, "Cellulitis ": 2.53328242977071, "Cholecystectomy ": 8.94217434109356, "Cholelithiasis ": 4.954964630147122, "Circumstance or information capable of leading to device use error ": 89.40968381714825, "Circumstance or information capable of leading to medication error ": 28.801118774679463, "Colon cancer ": 3.4066561469067125, "Coronary artery occlusion ": 8.89586596694438, "Cyst ": 2.459582049628099, "Decreased appetite ": 2.4648638895146715, "Dehydration ": 2.6537587880092874, "Device defective ": 27.50218025760453, "Device delivery system issue ": 34.04987237920876, "Device difficult to use ": 9.675071457351104, "Device failure ": 3.854957170903627, "Device issue ": 33.62678827150396, "Device leakage ": 115.81649423853864, "Device malfunction ": 33.639293559072655, "Device occlusion ": 7.533384969517858, "Device use issue ": 17.534758389233602, "Diabetes mellitus inadequate control ": 4.751849708131042, "Diabetic ketoacidosis ": 3.130921618612218, "Diabetic neuropathy ": 7.830225665618648, "Diverticulum ": 2.6846459932199074, "Drug delivery system issue ": 43.58628376827056, "Drug delivery system malfunction ": 8.673766473765868, "Drug dose omission by device ": 19.687545885695517, "Dyspepsia ": 2.31081558693828, "Eructation ": 11.22169393058593, "Essential hypertension ": 10.47784738645095, "Feeling jittery ": 2.5533641259696696, "Gallbladder disorder ": 7.263886961634887, "Gastroenteritis viral ": 4.597093660964562, "Gastrooesophageal reflux disease ": 2.250476123253049, "Glycosylated haemoglobin abnormal ": 9.81137658882837, "Glycosylated haemoglobin increased ": 21.4740385296052, "Hepatic steatosis ": 3.1533730983327506, "Hernia ": 4.603402508756814, "Hiatus hernia ": 2.074392765640138, "Hiccups ": 2.7150321398576494, "Hunger ": 3.2938966828212943, "Hypercholesterolaemia ": 3.685883396518293, "Hyperlipidaemia ": 4.420872022111512, "Hypophagia ": 5.147988576922387, "Illness ": 2.071372127864082, "Impaired gastric emptying ": 10.546640596722352, "Incorrect dose administered ": 12.117634579351042, "Incorrect dose administered by device ": 55.14875262704864, "Increased appetite ": 4.506957210023666, "Injection site abscess ": 24.50498032692051, "Injection site bruising ": 18.59734936713588, "Injection site cellulitis ": 26.736766198483966, "Injection site cyst ": 67.69157934369878, "Injection site discharge ": 82.56665540457304, "Injection site discolouration ": 16.6824662529012, "Injection site discomfort ": 4.841349528049299, "Injection site erythema ": 2.384277727697458, "Injection site extravasation ": 90.09055393472178, "Injection site haemorrhage ": 82.074174863281, "Injection site induration ": 8.691160783541305, "Injection site infection ": 22.28819826008692, "Injection site injury ": 33.231796607408334, "Injection site mass ": 80.01332610649331, "Injection site necrosis ": 5.6828267251085975, "Injection site nodule ": 388.8071772502229, "Injection site pain ": 3.123125430483474, "Injection site pruritus ": 9.29306652733537, "Injection site rash ": 5.837601091861755, "Injection site scab ": 56.7557451221051, "Injection site scar ": 40.95262671786841, "Injection site urticaria ": 15.17340043887058, "Injection site vesicles ": 7.670003761909322, "Injury associated with device ": 7.308267553787056, "Insulin-requiring type 2 diabetes mellitus ": 31.5742236418412, "Insurance issue ": 13.116615424905246, "Intentional device misuse ": 99.47828675714672, "Intentional product misuse ": 6.5403382336719655, "Jaundice cholestatic ": 4.363531748487131, "Limb injury ": 2.2469765588098336, "Lip swelling ": 2.115883565434862, "Lipase increased ": 7.919849003659774, "Localised infection ": 7.819829272515478, "Lymphoedema ": 2.0431123165066314, "Malignant melanoma ": 2.6930509632110757, "Mass ": 3.440559528329461, "Memory impairment ": 2.089332292815164, "Metastases to liver ": 4.116329768710287, "Metastases to peritoneum ": 5.416495187854698, "Metastatic neoplasm ": 5.667639540984428, "Muscle disorder ": 7.991330998583714, "Myocardial infarction ": 2.061323222620743, "Near death experience ": 4.248315792012976, "Neck injury ": 14.330651041379928, "Needle issue ": 37.59307232454269, "Nephrolithiasis ": 2.8362291717622337, "Nodule ": 4.519201336352137, "Obesity ": 3.0532159669409067, "Obstructive sleep apnoea syndrome ": 3.998902086463563, "Pancreatic carcinoma ": 16.353532438122055, "Pancreatic carcinoma metastatic ": 29.75688608270224, "Pancreatic cyst ": 10.7856489927379, "Pancreatic disorder ": 7.058984747317663, "Pancreatitis ": 13.29379487448506, "Pancreatitis acute ": 7.457948544560627, "Parkinson's disease ": 2.945994895410787, "Product dispensing error ": 2.939158479693294, "Product dose omission issue ": 7.021648117853322, "Product packaging quantity issue ": 38.02297957018376, "Product preparation issue ": 2.3377121911350414, "Product quality issue ": 16.076680641113548, "Product solubility abnormal ": 19.281671564516795, "Prostate cancer ": 3.679508494307686, "Prostatomegaly ": 6.004422029193521, "Radiotherapy ": 10.687305041830118, "Renal cyst ": 2.2557089531428205, "Retinal detachment ": 2.7174814349954635, "Road traffic accident ": 2.08191867192392, "Skin mass ": 10.135354899374036, "Stress ": 2.550168436074544, "Therapy cessation ": 6.06882401555604, "Thyroid cancer ": 5.823697970544982, "Thyroid mass ": 14.754103062646951, "Transient ischaemic attack ": 2.056739381157648, "Type 2 diabetes mellitus ": 7.495532290550348, "Underdose ": 2.3256064290790737, "Uterine cancer ": 3.748669625840797, "Weight decreased ": 7.575162487703294, "Weight fluctuation ": 8.161692824268334, "Weight increased ": 2.039368076335262, "Wrong technique in device usage process ": 52.990063599492, "Wrong technique in product usage process ": 4.06103647505537}
\ No newline at end of file
+{"Abortion spontaneous": 2.832749043401606, "Accident": 2.313101668958953, "Accidental exposure to product by child": 17.392392260974194, "Accidental overdose": 6.532707696951065, "Accidental poisoning": 54.6899067853232, "Affective disorder": 3.246687799819938, "Aggression": 2.1634620876394983, "Agitation": 2.205395844481697, "Agitation neonatal": 17.26696753349564, "Alcohol abuse": 25.50019191789911, "Alcohol interaction": 44.64250852991062, "Alcohol poisoning": 5.013936766491466, "Amniotic fluid volume decreased": 24.164366861405085, "Anaemia neonatal": 19.936950831729355, "Application site burn": 5.44373139349514, "Application site erythema": 4.781033774332136, "Application site haemorrhage": 9.483271172788715, "Application site hypersensitivity": 15.427691384519546, "Application site inflammation": 7.757389773055307, "Application site irritation": 6.100184107290469, "Application site pruritus": 8.072370564766905, "Application site rash": 16.76502574228821, "Application site 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"Communication disorder": 3.1939418594662747, "Compartment syndrome": 4.800253182177161, "Congenital anomaly": 4.115276581720223, "Constipation": 2.56439342865228, "Convulsive threshold lowered": 28.365090590396974, "Death": 2.655167993641467, "Defaecation urgency": 3.311696564130936, "Delirium": 2.0196034322170187, "Dental caries": 2.4011771865800062, "Dependence": 79.00426148510387, "Depressed level of consciousness": 3.760312236877415, "Depression": 2.8285013657578597, "Dermal cyst": 12.27195316013542, "Dermatitis contact": 2.0768509966574698, "Developmental delay": 14.494053851764043, "Disorientation": 2.1791082524449967, "Drowning": 11.91443177301148, "Drug abuse": 21.702545013072967, "Drug abuser": 19.685343215666727, "Drug delivery system removal": 68.43012578350323, "Drug dependence": 86.06992509283438, "Drug detoxification": 62.705382163006256, "Drug diversion": 28.686060335756373, "Drug effect less than expected": 5.534361664045555, "Drug interaction": 2.763403690199223, "Drug screen positive": 67.39039117982836, "Drug tolerance": 13.554122218892276, "Drug use disorder": 37.22909463069427, "Drug withdrawal syndrome": 27.81516101832861, "Drug withdrawal syndrome neonatal": 96.98426917810568, "Dysarthria": 2.546728590505028, "Endocarditis": 7.649005133574212, "Energy increased": 6.49203759473958, "Euphoric mood": 6.204583453474744, "Exposure during pregnancy": 3.163129479779517, "Exposure via breast milk": 39.0658361165897, "Foetal distress syndrome": 6.319591394235618, "Foetal exposure during pregnancy": 15.552875092357802, "Foetal growth restriction": 4.135604250406109, "Gastrointestinal motility disorder": 3.939111830684285, "Gingival recession": 9.224254111903605, "Hallucination": 2.481903376178692, "Hallucination, auditory": 2.490783556451839, "Hallucination, visual": 2.116230316771884, "Hepatitis C": 2.6137588688842754, "Homicidal ideation": 2.121751185524717, "Hormone level abnormal": 3.0175942692027333, "Hospitalisation": 2.111509180717235, "Hypercapnia": 2.857476730171905, "Hypertonia": 2.3929454086732624, "Hypoglycaemic coma": 3.256506660540679, "Impaired driving ability": 8.353738699388481, "Impaired quality of life": 4.112522967296689, "Impetigo": 6.110437616374979, "Inadequate analgesia": 22.17612625350558, "Incoherent": 6.045108822670555, "Infantile spitting up": 27.783480283499557, "Infertility": 7.951653155231626, "Inflammatory pain": 13.249911973109176, "Intentional product misuse": 9.572574174986295, "Intentional product use issue": 3.894590582186684, "Intentional self-injury": 2.680678589082045, "Intentional underdose": 33.62244515913804, "Intervertebral disc degeneration": 2.660208236170796, "Jaundice neonatal": 21.87128982870628, "Lactation insufficiency": 4.04626721859974, "Learning disability": 91.4968579963664, "Logorrhoea": 6.102262964174674, "Loss of employment": 4.584365703762968, "Low birth weight baby": 20.23023745173055, "Mastication disorder": 5.768495776191381, "Maternal exposure during pregnancy": 6.12831776851319, "Meconium aspiration syndrome": 55.59692578680711, "Mental disorder": 3.5958307231319715, "Miosis": 20.78114404614233, "Morning sickness": 18.20448632823347, "Multiple injuries": 2.9045386389607133, "Mydriasis": 2.4025492346698525, "Myelopathy": 6.320126074017229, "Neonatal respiratory distress": 14.080211529049611, "Neonatal respiratory distress syndrome": 3.0891076639240134, "Nephrosclerosis": 16.33678459881442, "Neurosis": 10.263710229728014, "Oesophagitis": 3.5535131139853817, "Oral administration complication": 42.8829442852114, "Overdose": 14.240315859458695, "Palmoplantar pustulosis": 16.083603235211974, "Pancreatitis chronic": 4.597750402030978, "Panic disorder": 4.884450278241646, "Paranoia": 2.949829083741751, "Parasomnia": 31.743506464049855, "Peripheral ischaemia": 2.100574646741852, "Persecutory delusion": 4.587230631108052, "Persistent depressive disorder": 13.702606485716736, "Personal relationship issue": 48.37616256134434, "Piloerection": 6.001751371460073, "Placenta praevia": 18.197897702411847, "Placental disorder": 19.87366516423533, "Placental hypertrophy": 529.150652957763, "Plantar fasciitis": 7.220886243513024, "Poisoning": 6.87541735748153, "Poor feeding infant": 20.10350829977817, "Post-traumatic stress disorder": 10.870707617440395, "Potentiating drug interaction": 2.120164249262097, "Pre-eclampsia": 6.525271893335568, "Premature baby": 9.71590289697576, "Premature delivery": 14.025992939408033, "Premature labour": 3.029869940054972, "Premature rupture of membranes": 7.449047492269636, "Premature separation of placenta": 5.748375293512157, "Prescribed overdose": 2.332966420873178, "Prescription drug used without a prescription": 8.007116152330504, "Procedural pain": 2.1642773954404824, "Product adhesion issue": 14.705013653484956, "Product preparation issue": 52.070351000802425, "Product prescribing issue": 4.784237068293692, "Product quality issue": 2.2108090515708283, "Psychomotor skills impaired": 2.2431788009353664, "Psychotic behaviour": 7.996880316394824, "Psychotic disorder": 2.161882248396548, "Pulmonary congestion": 4.3754424630309945, "Pulmonary oedema": 3.321221564743533, "Pulse absent": 2.7410714448794997, "Quadriparesis": 9.833412644520626, "Respiratory acidosis": 3.092783595545366, "Respiratory arrest": 4.293700570245658, "Respiratory depression": 14.340294111879576, "Respiratory disorder neonatal": 14.336940713770767, "Respiratory rate decreased": 5.968839978998704, "Rib fracture": 2.644110365144293, "Road traffic accident": 4.471958111123314, "Sarcopenia": 30.446492362089035, "Schizophrenia": 3.203582100184093, "Sciatica": 2.1693109145917133, "Seborrhoeic dermatitis": 5.302241692920689, "Secondary hypogonadism": 45.73791221897104, "Sedation": 5.069272311040873, "Selective eating disorder": 5.302241692920689, "Self-destructive behaviour": 5.28017772800524, "Serotonin syndrome": 3.966093547275528, "Skin abrasion": 2.631155511211812, "Skin irritation": 4.574671103096947, "Small for dates baby": 5.175580694411001, "Social anxiety disorder": 15.264361218347547, "Somnambulism": 35.8762778588666, "Somnolence": 2.2026473571810103, "Spinal osteoarthritis": 3.0111933315776684, "Spinal stenosis": 3.053649717834869, "Stillbirth": 4.06939722441936, "Stress cardiomyopathy": 2.486913848214246, "Substance abuse": 49.46701388083867, "Substance dependence": 5.164012211007461, "Substance use": 16.85408616980267, "Substance use disorder": 158.8569484602725, "Substance-induced psychotic disorder": 14.270745130389349, "Suicidal ideation": 2.987327755850113, "Suicide attempt": 2.726299447193559, "Suspected suicide": 3.898612564274484, "Therapeutic response delayed": 10.897642711489317, "Therapy interrupted": 2.5789724697234253, "Thermal burn": 29.17939767715857, "Tooth disorder": 2.26966948617384, "Toxicity to various agents": 9.781277989803137, "Tremor neonatal": 56.30373403400948, "Type IIa hyperlipidaemia": 53.41389673977547, "Umbilical cord around neck": 15.30048458405184, "Unresponsive to stimuli": 3.6504497657125055, "Vitamin B12 deficiency": 6.25179959335758, "Withdrawal syndrome": 12.953167806266832, "Wrong technique in product usage process": 2.938300600014369, "Yawning": 9.901584925826766}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/215.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/215.json
index 86f0bc85b5d..6d4ac712e77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/215.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/215.json
@@ -1 +1 @@
-{"Abdominal hernia ": 10.884716350995316, "Abdominal tenderness ": 2.6399743846188577, "Abnormal loss of weight ": 7.326786308921675, "Acquired diaphragmatic eventration ": 39.49797397591037, "Acute kidney injury ": 2.66414112265185, "Adenocarcinoma pancreas ": 220.0514409421921, "Adrenal adenoma ": 48.555329636039154, "Adrenal mass ": 27.44076390190085, "Amylase increased ": 5.246513096176721, "Anaemia of chronic disease ": 23.2573218001352, "Aortic arteriosclerosis ": 14.444661576728985, "Appendicectomy ": 15.156697003631898, "Arterial occlusive disease ": 2.295696457985284, "Arteriosclerosis ": 5.57568813475133, "Arteriosclerosis coronary artery ": 7.340670388812847, "Arthritis ": 2.191877763533141, "Ascites ": 5.16060959947885, "Atelectasis ": 8.327254198124502, "Autoimmune thyroiditis ": 6.35488335425773, "Barrett's oesophagus ": 6.360285941665228, "Benign pancreatic neoplasm ": 72.36487152243265, "Benign prostatic hyperplasia ": 10.812551405395268, "Bile duct adenocarcinoma ": 136.7899781858648, "Bile duct cancer ": 37.41705141092123, "Bile duct stenosis ": 38.51974539525071, "Bile duct stent insertion ": 213.21945798769596, "Bile duct stone ": 6.564460759168819, "Biliary dilatation ": 16.814749060546795, "Biliary dyskinesia ": 47.36012791478623, "Biliary obstruction ": 35.72931859108263, "Blood cholesterol increased ": 2.511166869299345, "Blood glucose abnormal ": 4.729786886055354, "Blood glucose decreased ": 10.095433237694916, "Blood glucose fluctuation ": 6.160157910798752, "Blood glucose increased ": 6.775495733939718, "Blood loss anaemia ": 4.24326773698921, "Blood triglycerides increased ": 7.668896028237928, "Body height decreased ": 5.856380915118072, "Breast conserving surgery ": 10.777439124763731, "Cancer pain ": 3.9114837722627223, "Cardiac murmur ": 3.011778049493324, "Cardiac pacemaker insertion ": 2.6532263708259225, "Carpal tunnel syndrome ": 2.909981130563528, "Cataract ": 3.0331457871395338, "Cataract operation ": 13.073975548849733, "Catheterisation cardiac ": 5.082865079975116, "Cholangiocarcinoma ": 10.526791795499086, "Cholangitis ": 8.09432931521846, "Cholangitis acute ": 18.52911236636841, "Cholecystectomy ": 26.493886455999068, "Cholecystitis ": 7.171918699960036, "Cholecystitis acute ": 8.964901186281852, "Cholecystitis chronic ": 39.24058079973306, "Cholelithiasis ": 18.790855081611348, "Chronic gastritis ": 3.4449357244123275, "Circumstance or information capable of leading to medication error ": 2.481284853379462, "Colitis ischaemic ": 3.4904774463724806, "Colon cancer ": 2.788786470719369, "Colorectal adenoma ": 20.822940479109377, "Complication associated with device ": 3.262646937582889, "Coronary arterial stent insertion ": 12.428340299175249, "Coronary artery bypass ": 5.515673891298287, "Coronary artery disease ": 4.830367515769646, "Coronary artery occlusion ": 2.820992169543418, "Coronary artery stenosis ": 2.541753336513328, "Cyst ": 2.294999103102726, "Decreased appetite ": 2.1198243372872647, "Dehydration ": 3.924098721849264, "Device delivery system issue ": 4.649818286858428, "Device issue ": 3.7718318427895663, "Device leakage ": 6.8978785488455605, "Device malfunction ": 3.97291368325473, "Device use issue ": 3.625350070257985, "Diabetes mellitus inadequate control ": 7.847008794553672, "Diabetic ketoacidosis ": 2.107470548018147, "Diabetic nephropathy ": 10.601798627392656, "Diabetic neuropathy ": 18.989934859311205, "Diabetic retinopathy ": 4.392459873595424, "Diverticulitis ": 4.721437047471437, "Diverticulum ": 8.88894968086237, "Diverticulum intestinal ": 9.519097822420362, "Ductal adenocarcinoma of pancreas ": 82.77309843270505, "Duodenal obstruction ": 41.2908445716403, "Duodenal ulcer ": 3.5073088472060245, "Duodenitis ": 13.78139755827861, "Dyslipidaemia ": 3.5159773124968674, "Dyspepsia ": 2.095497932222972, "Early satiety ": 28.94310438815108, "Eructation ": 4.1031336814865575, "Essential hypertension ": 7.666152884303497, "Exostosis ": 2.0948461308653394, "Failure to thrive ": 4.205563974512833, "Feeling jittery ": 4.095411907402606, "Flank pain ": 2.623543066663012, "Follicular thyroid cancer ": 62.100327209614754, "Gallbladder disorder ": 8.018638933051415, "Gallbladder operation ": 5.221135924767798, "Gastric bypass ": 10.311398945272376, "Gastritis ": 5.467658728013177, "Gastroenteritis ": 3.131032720511448, "Gastroenterostomy ": 97.0623562272919, "Gastrooesophageal reflux disease ": 3.873405957214678, "Glycosylated haemoglobin increased ": 11.171252323411396, "Goitre ": 31.809221402745628, "Gout ": 3.015934234049155, "Hepatic cancer ": 2.947015358870562, "Hepatic cancer metastatic ": 28.547028122901526, "Hepatic cirrhosis ": 3.053137954394757, "Hepatic cyst ": 10.055521341695576, "Hepatic lesion ": 6.904393071905728, "Hepatic mass ": 12.024211637252533, "Hepatic steatosis ": 9.350644960948664, "Hernia repair ": 13.749405786923012, "Hiatus hernia ": 4.68797654007014, "Hunger ": 3.876722424592612, "Hydronephrosis ": 2.5738949700547136, "Hypercholesterolaemia ": 9.085032833508189, "Hyperglycaemia ": 2.918997002838631, "Hyperlipidaemia ": 13.93052111593498, "Hypertriglyceridaemia ": 3.46721700548565, "Hypoglycaemia ": 2.4454183994974703, "Hypoglycaemic unconsciousness ": 3.6482375602523343, "Hypomagnesaemia ": 2.773870839339415, "Hypothyroidism ": 2.9668120296031213, "Hypovolaemia ": 2.153618768855323, "Hysterectomy ": 12.624110253195848, "Ileus ": 2.82373570948684, "Impaired gastric emptying ": 10.259747547109882, "Incorrect dose administered by device ": 3.9729771557288247, "Inguinal hernia ": 3.1636220843315157, "Injection site bruising ": 3.464263353827132, "Injection site extravasation ": 5.433490753360112, "Injection site haemorrhage ": 5.426434187367427, "Insulin resistance ": 4.568946468936606, "Insulin-requiring type 2 diabetes mellitus ": 102.04665456066388, "Intentional device misuse ": 19.66679124523517, "Intervertebral disc degeneration ": 4.3980560705519895, "Intestinal metastasis ": 19.22185324912504, "Intraductal papillary mucinous neoplasm ": 64.79127645870685, "Iron deficiency anaemia ": 4.925895063485154, "Jaundice cholestatic ": 30.374807251659902, "Laparoscopy ": 121.00273941163998, "Laparotomy ": 31.393207565366254, "Large intestine polyp ": 4.831315081878024, "Leukocytosis ": 2.449650134349874, "Limb injury ": 2.211694638895096, "Lipase increased ": 10.136331236647957, "Liver abscess ": 4.106544327383777, "Malignant ascites ": 77.72463427589034, "Malnutrition ": 7.607901465940682, "Medullary thyroid cancer ": 55.72367560562081, "Metastases to abdominal cavity ": 17.248697992406434, "Metastases to adrenals ": 10.333741608504498, "Metastases to liver ": 30.45572009179837, "Metastases to lung ": 12.670800529081014, "Metastases to lymph nodes ": 25.765809699884667, "Metastases to peritoneum ": 36.804315125463, "Metastases to spleen ": 30.26868209216557, "Metastatic neoplasm ": 7.273380179448467, "Nephrolithiasis ": 4.563248896987959, "Neuroendocrine tumour ": 8.674153217862413, "Non-alcoholic steatohepatitis ": 9.072284187549329, "Normocytic anaemia ": 3.55184204835388, "Obstruction gastric ": 31.22489130869108, "Obstructive pancreatitis ": 34.13640529153494, "Obstructive sleep apnoea syndrome ": 7.292328161370191, "Oedematous pancreatitis ": 11.54977510854166, "Osteoarthritis ": 2.7011947326082164, "Overweight ": 4.594623835629918, "Pancreatectomy ": 134.9346561572111, "Pancreatic carcinoma ": 145.43536473368553, "Pancreatic carcinoma metastatic ": 218.8257052472164, "Pancreatic carcinoma recurrent ": 108.53505549207446, "Pancreatic carcinoma stage IV ": 87.85846710344173, "Pancreatic cyst ": 37.945158051264414, "Pancreatic disorder ": 6.109646030140581, "Pancreatic duct dilatation ": 81.44228212874353, "Pancreatic duct obstruction ": 67.92853781353745, "Pancreatic enzymes increased ": 5.567986881249192, "Pancreatic failure ": 18.18703435115625, "Pancreatic mass ": 67.00228546997259, "Pancreatic neoplasm ": 32.80685181748222, "Pancreatic neuroendocrine tumour ": 44.55632003066437, "Pancreatic neuroendocrine tumour metastatic ": 96.14014129169658, "Pancreatic pseudocyst ": 26.2798904508502, "Pancreatic stent placement ": 93.48750618786488, "Pancreaticoduodenectomy ": 107.68938426721324, "Pancreatitis ": 31.44804119598424, "Pancreatitis acute ": 24.718934351883235, "Pancreatitis chronic ": 92.87566972861912, "Pancreatitis haemorrhagic ": 20.424036291162206, "Pancreatitis necrotising ": 21.51144230105459, "Pancreatitis relapsing ": 46.569648047079085, "Panic disorder ": 2.32823854958584, "Papillary thyroid cancer ": 76.32777601954106, "Peripheral venous disease ": 2.447988307281232, "Pneumobilia ": 96.8829292325847, "Polyp ": 2.813994962645586, "Portal hypertension ": 3.736345191910292, "Post procedural hypothyroidism ": 241.0856269030708, "Post procedural infection ": 3.6446276271560185, "Postoperative wound infection ": 3.716992369920854, "Product dose omission issue ": 2.600484910108261, "Product quality issue ": 4.809079677645833, "Prostatic calcification ": 72.36487152243265, "Prostatomegaly ": 4.505551160562772, "Pulmonary mass ": 7.945015212628883, "Radiotherapy ": 13.138150580608652, "Renal cyst ": 11.820188590118477, "Renal disorder ": 2.2197478446072907, "Renal failure ": 2.104690136528696, "Renal tubular necrosis ": 2.024606950689963, "Retinopathy ": 3.510448414763377, "Road traffic accident ": 2.113078741334117, "Rotator cuff repair ": 13.606263001410984, "Rotator cuff syndrome ": 2.704555257417912, "Sinus node dysfunction ": 3.329253637347524, "Sleep apnoea syndrome ": 4.132514895121318, "Small intestinal obstruction ": 2.865651068245033, "Spinal operation ": 4.561501882742915, "Spinal osteoarthritis ": 4.104653180950861, "Splenectomy ": 35.15420405709042, "Stent placement ": 6.044070256644217, "Stomach mass ": 30.33225054146053, "Stress ": 2.175542803836019, "Thyroid cancer ": 42.425484437229386, "Thyroid cancer metastatic ": 40.7296587505901, "Thyroid mass ": 19.895979414458694, "Thyroid neoplasm ": 9.93728604066932, "Thyroidectomy ": 9.939138463734446, "Umbilical hernia ": 8.505569508829964, "Urinary tract disorder ": 4.214876729977447, "Weight decreased ": 9.762070956572993, "Weight fluctuation ": 10.676920687446904, "Wrong technique in device usage process ": 3.4736591190419754}
\ No newline at end of file
+{"Acute graft versus host disease": 81.29891484665166, "Acute graft versus host disease in skin": 118.4034805952871, "Acute lymphocytic leukaemia": 57.448449464922845, "Acute lymphocytic leukaemia recurrent": 56.284012797622, "Acute myeloid leukaemia": 19.24598785197774, "Acute respiratory distress syndrome": 14.320446438032931, "Adenovirus infection": 48.6658719199235, "Bacterial sepsis": 83.33242876119397, "Blood culture positive": 103.77352728849492, "Bone marrow failure": 38.27667475952431, "Bone marrow leukaemic cell infiltration": 2456.0126545508742, "Bronchopulmonary aspergillosis": 26.42179859007554, "Cardiac failure": 3.03883947160782, "Cardiogenic shock": 15.663790544067131, "Chronic graft versus host disease": 92.25667860801164, "Cystitis haemorrhagic": 97.63855129890494, "Cytomegalovirus infection": 194.71393876786763, "Cytomegalovirus infection reactivation": 27.77254114733388, "Dermatitis bullous": 12.529835505686144, "Disease recurrence": 14.74881943694129, "Ejection fraction decreased": 16.800757351779417, "Encephalopathy": 7.479959172991069, "Engraftment syndrome": 413.5642157944732, "Epstein-Barr virus infection": 98.65928912553773, "Epstein-Barr virus infection reactivation": 168.89007609724024, "Febrile bone marrow aplasia": 74.02413595356012, "Febrile neutropenia": 11.183740004502177, "Gamma-glutamyltransferase increased": 3.423438738546759, "Graft versus host disease": 23.23780984134875, "Haematuria": 4.311988840851732, "Hepatic cytolysis": 18.580576274601707, "Hepatitis acute": 14.783695190770024, "Hepatosplenomegaly": 56.23841639202787, "Infection": 2.909542338639981, "Leukaemia recurrent": 121.42520941204472, "Lung disorder": 5.911660749875731, "Mucosal inflammation": 48.793652386192434, "Multiple organ dysfunction syndrome": 7.743620550804389, "Myocarditis": 8.446375965893624, "Neurotoxicity": 12.943401651148482, "Pericarditis": 3.152704432560703, "Platelet count increased": 17.440617916739587, "Post transplant lymphoproliferative disorder": 71.99214415824973, "Pseudomonal sepsis": 174.78341325570173, "Rash maculo-papular": 2.386765216578421, "Respiratory failure": 2.8657329280300163, "Sepsis": 8.610528958386942, "Septic shock": 21.38006151640097, "Serratia sepsis": 2701.909723011382, "Staphylococcal infection": 8.324231707801951, "Stomatitis": 14.75385260905805, "Thrombotic microangiopathy": 42.7143209847935, "Venoocclusive disease": 754.830182378999, "Venoocclusive liver disease": 271.66230054057127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/216.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/216.json
index 126c6f75606..7a4a56a6717 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/216.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/216.json
@@ -1 +1 @@
-{"Angioedema ": 17.53470246021304, "Drug hypersensitivity ": 11.280292227795975, "Drug ineffective ": 4.981604970328679, "Hereditary angioedema ": 355.3965786839803, "Off label use ": 10.556452015133576, "Prescribed overdose ": 54.40658618686044, "Stress ": 20.750398350407863, "Therapeutic product effect incomplete ": 6.700239562680315}
\ No newline at end of file
+{"Acidosis hyperchloraemic": 14.09672103581935, "Acute graft versus host disease": 192.9920830055666, "Acute graft versus host disease in intestine": 200.39752740763296, "Acute graft versus host disease in liver": 182.01213059481023, "Acute graft versus host disease in skin": 311.49959762102907, "Acute hepatic failure": 2.777938423503902, "Acute lymphocytic leukaemia": 10.01702996814508, "Acute myeloid leukaemia": 10.566208637525683, "Acute myeloid leukaemia recurrent": 55.11679271208983, "Acute respiratory distress syndrome": 12.638460184326512, "Adenovirus infection": 95.49759484446402, "Anal abscess": 4.573184472452145, "Aplasia pure red cell": 3.159338702518597, "Aplastic anaemia": 25.35717138716428, "Ascites": 3.592103124567649, "Aspergillus infection": 23.45629891576169, "Atrial flutter": 7.234353765867994, "Atrial thrombosis": 7.884580086702468, "Atrophy": 9.984890021961323, "Autoimmune haemolytic anaemia": 14.25040547493326, "BK virus infection": 147.7661858698862, "Bacteraemia": 25.732730182320285, "Bacterial infection": 5.93711609325994, "Bacterial sepsis": 25.104883183217183, "Blast crisis in myelogenous leukaemia": 20.95717322556629, "Blood bilirubin increased": 3.484120274481934, "Blood culture positive": 27.812910455059, "Blood follicle stimulating hormone increased": 189.9194493968507, "Blood lactate dehydrogenase increased": 3.0034501941004965, "Blood luteinising hormone increased": 295.5451688894767, "Bone marrow failure": 18.61035953968596, "Bone marrow transplant rejection": 39.87594989406452, "Bronchiectasis": 11.17548476214774, "Bronchopulmonary aspergillosis": 27.396401977610907, "Budd-Chiari syndrome": 44.90001464494112, "Candida infection": 6.310729553280905, "Capillary leak syndrome": 6.665657163890091, "Cardiac failure acute": 2.079989746461655, "Cardiac tamponade": 5.505084020878415, "Cardiotoxicity": 5.147829648346741, "Central hypothyroidism": 27.26437871188312, "Central nervous system lesion": 3.712340001241087, "Cerebral toxoplasmosis": 70.83970378825498, "Cervical dysplasia": 6.9879504237960655, "Chloroma": 93.9472273648396, "Chronic graft versus host disease": 170.5346021303958, "Chronic graft versus host disease in intestine": 138.30603592823593, "Chronic graft versus host disease in liver": 107.2665386797747, "Chronic graft versus host disease in skin": 138.56206796679737, "Chronic myeloid leukaemia": 4.06379189734301, "Clostridium difficile colitis": 8.374007657454358, "Clostridium difficile infection": 7.292770334992229, "Congenital aplasia": 13.5202056446611, "Coombs positive haemolytic anaemia": 22.02783973129844, "Cystitis haemorrhagic": 217.36388127118727, "Cystitis viral": 114.93256842262576, "Cytokine release syndrome": 2.2445921425675026, "Cytomegalovirus chorioretinitis": 61.37606974074674, "Cytomegalovirus colitis": 8.622062052116334, "Cytomegalovirus infection": 63.90168976221664, "Cytomegalovirus infection reactivation": 159.49728130234237, "Cytomegalovirus test positive": 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gastrointestinal tract": 86.1526663733048, "Graft versus host disease in liver": 44.585717975201376, "Graft versus host disease in lung": 106.08091308428784, "Graft versus host disease in skin": 139.27196764486726, "Granulocytopenia": 4.392633473387216, "Guillain-Barre syndrome": 2.5049190905976544, "Haematuria": 3.244451209741445, "Haemophagocytic lymphohistiocytosis": 12.725961671727896, "Haemorrhage intracranial": 2.717758090948571, "Hepatic failure": 3.61506945925111, "Hepatic necrosis": 9.061903191280749, "Hepatitis B reactivation": 5.719843764567004, "Hepatomegaly": 6.594300686592269, "Hepatorenal syndrome": 8.95288944053289, "Hepatotoxicity": 2.4296630495705824, "Herpes simplex": 15.237605784555637, "Herpes virus infection": 2.669803928079617, "Hodgkin's disease recurrent": 39.87594989406452, "Human herpesvirus 6 encephalitis": 118.40485894852011, "Human herpesvirus 6 infection": 61.97036442351029, "Human polyomavirus infection": 66.77542573358578, "Hyperammonaemia": 2.08932269352976, "Hyperbilirubinaemia": 3.875019812757828, "Hyperlipidaemia": 2.851583293921191, "Hypouricaemia": 40.703782705163256, "Idiopathic pneumonia syndrome": 163.14901252605057, "Infection": 3.869020681261068, "Infection reactivation": 55.085857217531455, "Intervertebral disc protrusion": 3.252380782849349, "JC virus infection": 40.14728292653586, "Kaposi's sarcoma": 14.87741669131619, "Keratitis": 5.709317209110184, "Klebsiella infection": 36.04715760486412, "Klebsiella sepsis": 17.170740857471497, "Laryngitis fungal": 102.72489640432362, "Left ventricular failure": 5.95183012182659, "Leukaemia": 3.0942402061274064, "Leukaemia recurrent": 70.85263174599095, "Leukoencephalopathy": 6.550576585994994, "Lower respiratory tract infection fungal": 48.57196766126733, "Lung disorder": 2.366287194491968, "Lung opacity": 4.044633786583161, "Lymphopenia": 2.970720101187069, "Lymphoproliferative disorder": 17.7821947715555, "Marrow hyperplasia": 17.46706755226175, "Meningitis 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265.4898838320304, "Pancreatitis haemorrhagic": 35.41603743977941, "Pancytopenia": 9.012373282417686, "Pathogen resistance": 3.80098741342062, "Pericardial effusion": 5.191159104314595, "Pleural effusion": 2.5399788152717377, "Pneumatosis intestinalis": 7.57149453633704, "Pneumocystis jirovecii pneumonia": 8.024730618495976, "Pneumonia": 2.1043786470593684, "Pneumonia bacterial": 4.192279288135008, "Pneumonia cytomegaloviral": 48.73794823736795, "Pneumonia fungal": 23.117796142516063, "Pneumonia klebsiella": 21.1292913803044, "Pneumonitis": 4.5497526230654906, "Pneumothorax": 2.385592001517738, "Polyomavirus viraemia": 241.3264522703969, "Post transplant lymphoproliferative disorder": 51.59080792676637, "Posterior reversible encephalopathy syndrome": 19.11175806849752, "Premature menopause": 114.5139636956068, "Primary hypogonadism": 400.6407157717903, "Product administered to patient of inappropriate age": 11.647684250870563, "Product use in unapproved indication": 9.454030391480542, "Progressive multifocal leukoencephalopathy": 16.862695294286763, "Pseudomonal sepsis": 13.53753148283174, "Pseudomonas infection": 6.90218685328443, "Pulmonary alveolar haemorrhage": 10.699623431443188, "Pulmonary arterial hypertension": 4.645262541654477, "Pulmonary haemorrhage": 10.833685167464573, "Pulmonary hypertension": 6.152317406385167, "Pulmonary toxicity": 2.652808012912645, "Pulmonary veno-occlusive disease": 113.45779562216876, "Recurrent cancer": 12.877251636730543, "Renal tubular injury": 49.368869753501215, "Respiratory disorder": 2.182677422179451, "Respiratory distress": 2.2382076058041607, "Respiratory failure": 6.77204347829629, "Respiratory syncytial virus infection": 3.965564028614153, "Respiratory tract infection fungal": 41.7443111865362, "Retinitis viral": 479.0125204868015, "Retinopathy haemorrhagic": 209.822544438118, "Rhinovirus infection": 16.99197113677949, "Right ventricular failure": 4.982621938883884, "Second primary malignancy": 5.628622856582986, "Sepsis": 7.647149353885082, "Septic shock": 7.994696763568672, "Shock haemorrhagic": 3.634591023744837, "Skin hyperpigmentation": 2.7976045944644503, "Skin toxicity": 14.112464618849586, "Spinal stenosis": 6.291970245581363, "Splenomegaly": 2.046340590533707, "Staphylococcal bacteraemia": 13.388025783971733, "Staphylococcal infection": 6.012793322062258, "Staphylococcal sepsis": 13.724922913484802, "Stenotrophomonas infection": 11.470870940333985, "Stomatitis": 7.139853964495369, "Streptococcal bacteraemia": 97.44175660164385, "Systemic candida": 11.363384083501405, "Systemic inflammatory response syndrome": 4.750479491432523, "T-lymphocyte count decreased": 34.34867236203208, "Testicular atrophy": 56.331684733474304, "Therapy non-responder": 2.040369935604096, "Thrombocytopenia": 3.6686053629749376, "Thrombotic microangiopathy": 59.18989048012737, "Thrombotic thrombocytopenic purpura": 9.791256126763768, "Toxic encephalopathy": 3.9532227230794126, "Toxoplasmosis": 62.74887632054162, "Transplant failure": 135.44738848086695, "Transplant rejection": 19.308500607536377, "Traumatic lung injury": 12.407910060299004, "Tubulointerstitial nephritis": 3.4600422468209007, "Urinary tract obstruction": 15.605580871404497, "Vanishing bile duct syndrome": 45.20995405035068, "Varicella zoster virus infection": 20.352888633884263, "Venoocclusive disease": 300.03751762238073, "Venoocclusive liver disease": 299.8323982957023, "Viral haemorrhagic cystitis": 247.14721385163972, "Viral infection": 5.556610952254267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/217.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/217.json
index 25542acdc4d..b17efd64c60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/217.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/217.json
@@ -1 +1 @@
-{"Anaemia ": 4.103917077824526, "Bone pain ": 2.7723359135096217, "Disease progression ": 5.120008051617773, "Febrile neutropenia ": 19.070954794234314, "Flushing ": 2.6711695197296224, "Haematuria ": 12.222986977602348, "Haemoglobin decreased ": 3.2075849542578747, "Hepatotoxicity ": 5.925754882445448, "Hormone-refractory prostate cancer ": 845.3219083029279, "Hot flush ": 2.287684729266098, "Hyphaema ": 377.29541831882256, "Leukopenia ": 2.059640393139203, "Malignant neoplasm progression ": 23.794316321203663, "Metastases to bone ": 76.68625987070743, "Metastases to liver ": 9.335836788883592, "Metastases to lymph nodes ": 58.64291724211469, "Metastases to spine ": 65.18818324664026, "Metastasis ": 22.875354779777588, "Neuropathy peripheral ": 5.302232128884639, "Neutropenia ": 5.358074142441842, "Neutrophil count decreased ": 8.616869479222915, "Osteonecrosis of jaw ": 17.032282791715605, "Platelet count decreased ": 3.5686743213201964, "Prostate cancer ": 27.93142400814743, "Prostate cancer metastatic ": 939.8044844651956, "Prostatic specific antigen increased ": 170.76217460249023, "Sepsis ": 3.73342175975934, "Thrombocytopenia ": 3.0246419270991667, "Treatment failure ": 2.291063841935272, "Urinary retention ": 3.253260962752495}
\ No newline at end of file
+{"Abortion spontaneous": 11.042530920582866, "Alcohol poisoning": 65.59706160161677, "Drug dependence": 4.887444626431577, "Drug titration error": 1356.4727640371566, "Drug withdrawal syndrome": 9.062927083250036, "Drug withdrawal syndrome neonatal": 71.03492023019396, "Exposure via breast milk": 41.70322730908055, "Foetal exposure during pregnancy": 6.855405136629372, "Gestational diabetes": 63.6846969407586, "Hyperhidrosis": 2.217549279028442, "Injection site abscess": 90.3706894690186, "Injection site erythema": 11.58112562317231, "Injection site induration": 14.16411226087345, "Injection site inflammation": 2.3447024669156016, "Injection site mass": 132.48201321544602, "Injection site nodule": 101.10611988042058, "Injection site pain": 5.8166073105772, "Injection site pruritus": 16.98901595649729, "Injection site rash": 17.38515844174335, "Injection site reaction": 3.042190760083189, "Injection site swelling": 8.387197302836425, "Injection site warmth": 2.733437071209195, "Jaundice neonatal": 200.11772087021816, "Maternal exposure during pregnancy": 13.16100771631348, "Oedema peripheral": 2.7254150985892056, "Overdose": 2.4082585554776474, "Poor feeding infant": 160.53676347776343, "Premature baby": 5.547184045710002, "Respiratory depression": 12.637224958243204, "Toxicity to various agents": 5.651454062519102, "Urinary retention": 6.081981140639653, "Withdrawal syndrome": 60.19141039914823, "Yawning": 74.95806986209539}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/218.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/218.json
index e9b3024c273..acf3e6e7656 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/218.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/218.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 9.046682715422463, "Ageusia ": 2.0212394898688397, "Alanine aminotransferase increased ": 3.041383162960215, "Amylase increased ": 3.057318185318336, "Anal fistula ": 7.979772157139022, "Aortic dissection ": 5.651897475790106, "Ascites ": 3.794491057270093, "Aspartate aminotransferase increased ": 3.6081366697251753, "Biliary obstruction ": 6.74505223900663, "Blood albumin decreased ": 3.550104651418957, "Blood calcium decreased ": 3.887987592434971, "Blood magnesium decreased ": 4.089025199040412, "Blood pressure increased ": 3.6499840314068215, "Blood thyroid stimulating hormone increased ": 11.051661152142914, "Bone lesion ": 8.067660968932168, "Cancer pain ": 27.41865617305037, "Cholangitis ": 6.353758020564221, "Cholecystitis ": 2.289180729189178, "Clear cell renal cell carcinoma ": 21.104395247704208, "Colitis ": 2.1689359322287887, "Constipation ": 3.1193502444069714, "Decreased appetite ": 6.246333138449481, "Decubitus ulcer ": 3.3648240365173456, "Dehydration ": 2.6896844134199736, "Dermatitis acneiform ": 5.175131553341047, "Diarrhoea ": 5.442660711544802, "Disease progression ": 10.419967310966284, "Dry skin ": 5.450024643836324, "Dysgeusia ": 3.64250719875444, "Dysphonia ": 6.049590560859276, "Enterocolitis ": 2.977205897804604, "Gastrointestinal perforation ": 10.47929390275256, "Gastrointestinal toxicity ": 5.031957878064786, "Haemophagocytic lymphohistiocytosis ": 2.0357375667300777, "Hair colour changes ": 23.05397569835138, "Hepatic cancer ": 3.132317733957516, "Hepatic cytolysis ": 2.5096515394877303, "Hepatic encephalopathy ": 6.089680791488418, "Hepatic function abnormal ": 7.711501273654812, "Hepatocellular carcinoma ": 23.984397296438274, "Hepatotoxicity ": 3.343523441009091, "Hyperkeratosis ": 13.13184889222622, "Hypertension ": 5.984146803096716, "Hyperthyroidism ": 4.9834473257923735, "Hypertransaminasaemia ": 5.466048482784253, "Hypoalbuminaemia ": 4.693687742726391, "Hypocalcaemia ": 6.104643418078428, "Hypomagnesaemia ": 7.627779476893026, "Hypothyroidism ": 28.96744611916492, "Ileus ": 2.129745645934271, "Immune-mediated enterocolitis ": 4.612208180959077, "Immune-mediated hepatic disorder ": 10.445681181034123, "Immune-mediated lung disease ": 5.670059651046584, "Impaired healing ": 4.975864512822222, "Inappropriate schedule of product administration ": 3.311076164933438, "Interstitial lung disease ": 3.473091488446198, "Intestinal metastasis ": 28.615613417368333, "Intestinal perforation ": 5.225968163636565, "Intra-abdominal fluid collection ": 12.841478638522553, "Large intestine perforation ": 9.639674328077994, "Liver disorder ": 6.030318712884438, "Liver function test increased ": 3.3861393973201386, "Lumbar vertebral fracture ": 4.972943505432412, "Lung opacity ": 3.098478607659696, "Malignant neoplasm progression ": 14.663837198358197, "Malignant pleural effusion ": 13.35405582847828, "Metastases to adrenals ": 12.398751952132695, "Metastases to bone ": 16.261267148832726, "Metastases to central nervous system ": 9.843372525467856, "Metastases to liver ": 5.536644643945167, "Metastases to lung ": 16.957870119289613, "Metastases to lymph nodes ": 5.65517235426344, "Metastases to pancreas ": 55.95373952908467, "Metastases to peritoneum ": 5.543007576096178, "Metastases to spine ": 12.997056285401468, "Metastasis ": 2.8260810925846016, "Metastatic renal cell carcinoma ": 14.596056886098031, "Mucosal inflammation ": 11.877159368091853, "Nephrotic syndrome ": 5.8287386631001405, "Off label use ": 2.0159166403217985, "Oral mucosal blistering ": 2.298622037959301, "Oral pain ": 4.216097954438656, "Osteonecrosis of jaw ": 22.022776711413727, "Palmar-plantar erythrodysaesthesia syndrome ": 62.66580624189505, "Performance status decreased ": 3.6771202130970737, "Peripheral ischaemia ": 4.066078301618449, "Platelet count decreased ": 3.0688971239128597, "Pleural effusion ": 2.4287924215629757, "Pneumatosis intestinalis ": 9.93382171689049, "Pneumonia aspiration ": 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"Thyroid hormones increased ": 19.111157908554137, "Thyroiditis ": 9.30495728638366, "Tooth disorder ": 3.4531111992285406, "Tumour haemorrhage ": 8.396707796121122, "Tumour necrosis ": 19.21074184229666, "Weight decreased ": 4.01858201042941}
\ No newline at end of file
+{"Adenocarcinoma pancreas": 26.610663768283214, "Amylase increased": 2.435030134499657, "Atelectasis": 2.654626116354473, "Benign prostatic hyperplasia": 3.1059495199926874, "Blood cholesterol abnormal": 3.732671193689254, "Blood glucose abnormal": 4.652338023207815, "Blood glucose decreased": 5.714117038877999, "Blood glucose fluctuation": 5.38511391259352, "Blood glucose increased": 5.571961439987646, "Blood triglycerides increased": 2.5157375051068445, "Body height decreased": 9.564275572231058, "Body temperature": 5.056963543174196, "Breast cancer female": 4.057599424263143, "Cardiac flutter": 2.136243225275757, "Carotid artery occlusion": 3.0418654786908625, "Carpal tunnel syndrome": 2.458792537481169, "Cataract": 2.6498002734228523, "Cholecystectomy": 5.700716357378919, "Cholelithiasis": 3.158734111083962, "Circumstance or information capable of leading to device use error": 57.00122048211932, "Circumstance or information capable of leading to medication error": 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5.203224724300128, "Wrong technique in device usage process": 33.77845537236623, "Wrong technique in product usage process": 2.588771715187087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/219.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/219.json
index ef798eabef9..fec5ef407cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/219.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/219.json
@@ -1 +1 @@
-{"Blood HIV RNA increased ": 190.97613193718212, "Depressed mood ": 5.646975128061232, "Discomfort ": 2.8708342729653125, "Drug level decreased ": 36.412762699084695, "Feeling hot ": 2.3422892230098125, "Inappropriate schedule of product administration ": 3.686343955482892, "Injection site nodule ": 86.06832264683266, "Injection site pain ": 10.967564639171965, "Injection site reaction ": 4.021881858591831, "Injection site swelling ": 2.195539606297466, "Pain ": 2.297679117049065, "Pathogen resistance ": 184.0805572413363, "Suicidal ideation ": 2.390588825279849, "Treatment failure ": 4.669278648627319, "Treatment noncompliance ": 8.945569614505716, "Viral load increased ": 207.4362275517437, "Viral mutation identified ": 277.473330570674, "Virologic failure ": 308.41636702520475, "Wrong technique in product usage process ": 5.292154298730349}
\ No newline at end of file
+{"Abdominal hernia": 10.884716350995316, "Abdominal tenderness": 2.6399743846188577, "Abnormal loss of weight": 7.326786308921675, "Acquired diaphragmatic eventration": 39.49797397591037, "Acute kidney injury": 2.66414112265185, "Adenocarcinoma pancreas": 220.0514409421921, "Adrenal adenoma": 48.555329636039154, "Adrenal mass": 27.44076390190085, "Amylase increased": 5.246513096176721, "Anaemia of chronic disease": 23.2573218001352, "Aortic arteriosclerosis": 14.444661576728985, "Appendicectomy": 15.156697003631898, "Arterial occlusive disease": 2.295696457985284, "Arteriosclerosis": 5.57568813475133, "Arteriosclerosis coronary artery": 7.340670388812847, "Arthritis": 2.191877763533141, "Ascites": 5.16060959947885, "Atelectasis": 8.327254198124502, "Autoimmune thyroiditis": 6.35488335425773, "Barrett's oesophagus": 6.360285941665228, "Benign pancreatic neoplasm": 72.36487152243265, "Benign prostatic hyperplasia": 10.812551405395268, "Bile duct adenocarcinoma": 136.7899781858648, "Bile 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"Obstructive pancreatitis": 34.13640529153494, "Obstructive sleep apnoea syndrome": 7.292328161370191, "Oedematous pancreatitis": 11.54977510854166, "Osteoarthritis": 2.7011947326082164, "Overweight": 4.594623835629918, "Pancreatectomy": 134.9346561572111, "Pancreatic carcinoma": 145.43536473368553, "Pancreatic carcinoma metastatic": 218.8257052472164, "Pancreatic carcinoma recurrent": 108.53505549207446, "Pancreatic carcinoma stage IV": 87.85846710344173, "Pancreatic cyst": 37.945158051264414, "Pancreatic disorder": 6.109646030140581, "Pancreatic duct dilatation": 81.44228212874353, "Pancreatic duct obstruction": 67.92853781353745, "Pancreatic enzymes increased": 5.567986881249192, "Pancreatic failure": 18.18703435115625, "Pancreatic mass": 67.00228546997259, "Pancreatic neoplasm": 32.80685181748222, "Pancreatic neuroendocrine tumour": 44.55632003066437, "Pancreatic neuroendocrine tumour metastatic": 96.14014129169658, "Pancreatic pseudocyst": 26.2798904508502, "Pancreatic stent placement": 93.48750618786488, "Pancreaticoduodenectomy": 107.68938426721324, "Pancreatitis": 31.44804119598424, "Pancreatitis acute": 24.718934351883235, "Pancreatitis chronic": 92.87566972861912, "Pancreatitis haemorrhagic": 20.424036291162206, "Pancreatitis necrotising": 21.51144230105459, "Pancreatitis relapsing": 46.569648047079085, "Panic disorder": 2.32823854958584, "Papillary thyroid cancer": 76.32777601954106, "Peripheral venous disease": 2.447988307281232, "Pneumobilia": 96.8829292325847, "Polyp": 2.813994962645586, "Portal hypertension": 3.736345191910292, "Post procedural hypothyroidism": 241.0856269030708, "Post procedural infection": 3.6446276271560185, "Postoperative wound infection": 3.716992369920854, "Product dose omission issue": 2.600484910108261, "Product quality issue": 4.809079677645833, "Prostatic calcification": 72.36487152243265, "Prostatomegaly": 4.505551160562772, "Pulmonary mass": 7.945015212628883, "Radiotherapy": 13.138150580608652, "Renal cyst": 11.820188590118477, "Renal disorder": 2.219419300858274, "Renal failure": 2.104690136528696, "Renal tubular necrosis": 2.024606950689963, "Retinopathy": 3.510448414763377, "Road traffic accident": 2.113078741334117, "Rotator cuff repair": 13.606263001410984, "Rotator cuff syndrome": 2.704555257417912, "Sinus node dysfunction": 3.329253637347524, "Sleep apnoea syndrome": 4.130673385689277, "Small intestinal obstruction": 2.865651068245033, "Spinal operation": 4.561501882742915, "Spinal osteoarthritis": 4.104653180950861, "Splenectomy": 35.15420405709042, "Stent placement": 6.044070256644217, "Stomach mass": 30.33225054146053, "Stress": 2.175542803836019, "Thyroid cancer": 42.425484437229386, "Thyroid cancer metastatic": 40.7296587505901, "Thyroid mass": 19.895979414458694, "Thyroid neoplasm": 9.93728604066932, "Thyroidectomy": 9.939138463734446, "Umbilical hernia": 8.505569508829964, "Urinary tract disorder": 4.214876729977447, "Weight decreased": 9.762070956572993, "Weight fluctuation": 10.676920687446904, "Wrong technique in device usage process": 3.4736591190419754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/22.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/22.json
index 0e55ab59179..197f5f34cdd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/22.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/22.json
@@ -1 +1 @@
-{"Acute generalised exanthematous pustulosis ": 8.913034987531725, "Acute kidney injury ": 2.15178867472212, "Acute myocardial infarction ": 3.4894149315316, "Alanine aminotransferase increased ": 3.390804437383316, "Altered state of consciousness ": 6.030206563666552, "Aspartate aminotransferase increased ": 3.0329275753086717, "Bladder cancer ": 23.641552064340974, "Blood alkaline phosphatase increased ": 2.145710677522501, "Blood creatine phosphokinase increased ": 2.284566022785265, "Blood glucose decreased ": 9.874235775866737, "Blood glucose fluctuation ": 4.793153217274795, "Blood glucose increased ": 6.531088396334462, "Blood lactate dehydrogenase increased ": 2.7912249829889437, "Blood potassium decreased ": 3.094570723585333, "Blood urea increased ": 2.704378260067727, "Cardiac failure ": 3.260921608008581, "Cardiac failure congestive ": 9.667450362437316, "Cardiomegaly ": 11.787601472968312, "Cataract ": 6.792442457169299, "Cold sweat ": 3.240249888390692, "Coronary artery disease ": 7.206214271665215, "Dehydration ": 2.0219064593827034, "Depressed level of consciousness ": 3.0322508710405143, "Diabetes mellitus inadequate control ": 10.314417524568984, "Diabetic ketoacidosis ": 9.57211123719186, "Drug interaction ": 3.013931374908641, "Fluid retention ": 9.47395991303104, "Gamma-glutamyltransferase increased ": 4.159142762667941, "Gastrooesophageal reflux disease ": 2.4204642150151243, "Glycosylated haemoglobin increased ": 10.490180977232145, "Haemoptysis ": 2.2807410413479507, "Hepatic cirrhosis ": 4.167640976238321, "Hepatic failure ": 3.316929287405668, "Hepatic function abnormal ": 3.044585180215502, "Hepatic steatosis ": 4.236753654067889, "Hiatus hernia ": 6.222411685293688, "Hyperglycaemia ": 2.503913701173462, "Hypoglycaemia ": 19.16392981556364, "Hypoglycaemic coma ": 12.834957152131125, "Incorrect dose administered ": 2.120190454793858, "Interstitial lung disease ": 2.4141536791469664, "Irritable bowel syndrome ": 5.018076396068219, "Lactic acidosis ": 3.958809395203219, "Left ventricular hypertrophy ": 14.494051311241712, "Liver disorder ": 3.548193830579446, "Liver injury ": 4.949751787472818, "Macular oedema ": 13.124275732943987, "Medication error ": 4.340907312744745, "Mental impairment ": 3.008330778334653, "Metabolic acidosis ": 2.613109270406352, "Multiple allergies ": 34.3031300088349, "Myocardial infarction ": 3.5967436696322275, "Non-cardiac chest pain ": 35.88399149032056, "Oedema ": 4.965627294272026, "Oedema peripheral ": 3.845394188213933, "Pancreatic carcinoma ": 3.04327444927231, "Pancreatitis ": 2.014278443396581, "Pleural effusion ": 2.096929839241975, "Pulmonary oedema ": 5.180907871814076, "Reflux gastritis ": 43.27318230488139, "Rhabdomyolysis ": 2.3574396541673592, "Skin ulcer ": 2.8883106553108173, "Treatment noncompliance ": 3.1333872148729798, "Urinary incontinence ": 2.7620160898155084, "Urine output decreased ": 9.787651201373915, "Weight increased ": 6.6466406298862}
\ No newline at end of file
+{"Hypoglycaemia": 7.467673101849119}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/220.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/220.json
index 84abc31d0f2..a3c0d03f03c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/220.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/220.json
@@ -1 +1 @@
-{"Diarrhoea ": 2.72052845206641, "Hepatocellular carcinoma ": 29.996389152386485, "Malignant neoplasm progression ": 23.020014512618467, "Palmar-plantar erythrodysaesthesia syndrome ": 27.602612950673223}
\ No newline at end of file
+{"Angioedema": 17.53470246021304, "Drug hypersensitivity": 11.280292227795975, "Drug ineffective": 4.981568142714447, "Hereditary angioedema": 355.3965786839803, "Off label use": 10.556036139359549, "Prescribed overdose": 54.40658618686044, "Stress": 20.750398350407863, "Therapeutic product effect incomplete": 6.700239562680315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/221.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/221.json
index 7907c685c61..18857f62412 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/221.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/221.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 16.416231902655245, "Anaemia ": 2.665708319608646, "Anaphylactic reaction ": 3.154304234305521, "Anaphylactic shock ": 2.5660765514582184, "Anaphylactoid reaction ": 5.894912179903048, "Aphthous ulcer ": 2.2152020209205, "Ascites ": 4.495874422105774, "Back pain ": 4.11807273787603, "Blood alkaline phosphatase increased ": 2.0265810399343835, "Brain oedema ": 2.2878285002293035, "Breast cancer metastatic ": 13.844215625537611, "Bronchospasm ": 6.762408595565901, "Candida infection ": 2.6094743054828635, "Cardiogenic shock ": 2.455242648088, "Cardiotoxicity ": 20.606775732460548, "Cerebral toxoplasmosis ": 51.55851123437852, "Chest discomfort ": 2.7024169928679136, "Cyanosis ": 3.906544149440784, "Dermatitis ": 3.7221453986412527, "Dermatitis bullous ": 6.755571905295695, "Dermatitis exfoliative generalised ": 2.9702628391934014, "Desmoplastic small round cell tumour ": 354.2972950340737, "Diffuse large B-cell lymphoma ": 14.31536208390516, "Diffuse large B-cell lymphoma recurrent ": 20.610196016135923, "Diffuse large B-cell lymphoma refractory ": 103.41626631044566, "Dilated cardiomyopathy ": 6.819344488332185, "Disease progression ": 6.799625397537933, "Dysgraphia ": 6.83519294491055, "Ejection fraction decreased ": 5.790505029138122, "Epstein-Barr virus infection ": 8.937936264537738, "Erythema ": 4.70654897127806, "Extravasation ": 24.702306206251336, "Febrile neutropenia ": 8.438589942503333, "Feeling hot ": 2.12627571503587, "Flushing ": 12.435846694801675, "Gastric ulcer ": 3.1229079656057785, "Haematotoxicity ": 12.74634902097489, "Haemorrhage intracranial ": 2.6532110974691308, "Hepatitis cholestatic ": 2.79778209103456, "Hepatotoxicity ": 3.693891311750168, "Hypersensitivity ": 4.083071907326811, "Hypertransaminasaemia ": 2.337656610588982, "Hypoxia ": 2.9732175357673745, "Infusion related reaction ": 27.69827858036788, "Infusion site reaction ": 16.34110469836217, "Interstitial lung disease ": 14.952238530596354, "Intestinal obstruction ": 4.048924344642032, "Laryngeal oedema ": 4.306993799886247, "Leukopenia ": 4.094452483483853, "Malignant neoplasm progression ": 3.0948885531340853, "Mantle cell lymphoma recurrent ": 129.70878503950638, "Metastases to bone ": 3.441742769172808, "Metastases to liver ": 7.25386423540664, "Metastases to lymph nodes ": 9.765847469944289, "Metastases to peritoneum ": 32.53880288847138, "Mouth ulceration ": 2.9870909385078663, "Mucosal inflammation ": 16.872895737343462, "Multiple-drug resistance ": 7.648590483363011, "Myelodysplastic syndrome ": 6.218518014670228, "Neoplasm progression ": 6.484491072544475, "Neurological symptom ": 3.571900301581749, "Neuropathy peripheral ": 2.499084852280907, "Neurotoxicity ": 2.080584492222345, "Neutropenia ": 7.356354952881211, "Neutropenic sepsis ": 9.34679140187509, "Neutrophil count increased ": 4.85518163478879, "Off label use ": 6.632817406338891, "Ovarian cancer ": 27.03620824413983, "Palmar-plantar erythrodysaesthesia syndrome ": 58.44418964901055, "Pancytopenia ": 5.75086480447691, "Plasma cell myeloma ": 6.550785786912292, "Plasma cell myeloma recurrent ": 21.28066622512318, "Pneumonitis ": 2.416346374017764, "Polyneuropathy ": 4.035874746464884, "Post transplant lymphoproliferative disorder ": 20.86388934609301, "Product use in unapproved indication ": 15.357781274529025, "Progressive multifocal leukoencephalopathy ": 11.182075505572945, "Second primary malignancy ": 3.849320436811404, "Sense of oppression ": 11.278713760496354, "Sepsis ": 2.761768953368004, "Serous cystadenocarcinoma ovary ": 699.3842590766859, "Skin exfoliation ": 3.4631216770196502, "Skin hyperpigmentation ": 9.01758605148926, "Skin lesion ": 2.308551366460995, "Skin reaction ": 4.8504101124817645, "Skin toxicity ": 23.52213784113808, "Skin ulcer ": 3.1359534856752225, "Smooth muscle cell neoplasm ": 191.984106825042, "Stomatitis ": 7.331746732032793, "Throat tightness ": 2.1973748271421694, "Thrombocytopenia ": 3.5208548785844664, "Toxic epidermal necrolysis ": 2.360747061845563, "Toxic skin eruption ": 7.479793148253372, "Transaminases increased ": 2.8789548406255934}
\ No newline at end of file
+{"Anaemia": 4.094103382697562, "Bone pain": 2.7657154426541912, "Disease progression": 5.107772194578053, "Febrile neutropenia": 19.02533671700152, "Flushing": 2.664790638988485, "Haematuria": 12.193773802825952, "Haemoglobin decreased": 3.199922207719293, "Hepatotoxicity": 5.911603901428573, "Hormone-refractory prostate cancer": 843.3002878261087, "Hot flush": 2.2822218985584697, "Hyphaema": 376.3944572979013, "Leukopenia": 2.054462650738482, "Malignant neoplasm progression": 23.737309177638537, "Metastases to bone": 76.50284239364831, "Metastases to liver": 9.313540304646349, "Metastases to lymph nodes": 58.50279462978232, "Metastases to spine": 65.03250451774127, "Metastasis": 22.82073299100337, "Neuropathy peripheral": 5.289401312244682, "Neutropenia": 5.345031420125567, "Neutrophil count decreased": 8.59627498290832, "Osteonecrosis of jaw": 16.99161096425291, "Platelet count decreased": 3.560146912515055, "Prostate cancer": 27.86466191457334, "Prostate cancer metastatic": 937.555949351506, "Prostatic specific antigen increased": 170.35355658906403, "Sepsis": 3.724502818244416, "Thrombocytopenia": 3.0171288536612573, "Treatment failure": 2.2855929421456955, "Urinary retention": 3.2454920203020583}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/222.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/222.json
index 4e7a2d07445..81010dc1f31 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/222.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/222.json
@@ -1 +1 @@
-{"Balance disorder ": 24.5753568888814, "Blood calcium decreased ": 189.47457383055595, "Cognitive disorder ": 47.04701700739756, "Constipation ": 12.35139713373563, "Creatinine renal clearance decreased ": 239.34372577795668, "Creatinine renal clearance increased ": 1702.9612475917645, "Depressed level of consciousness ": 31.955032084904374, "Drug abuse ": 25.059676152125206, "Drug dependence ": 6.506951319547394, "Drug interaction ": 8.572566116896256, "Dyspnoea ": 2.4826246834346364, "Fall ": 8.56948865199568, "Hypotension ": 7.728082001329624, "Irritability ": 6.626050056784711, "Mobility decreased ": 30.252681634466477, "Multiple drug therapy ": 1276.726816297091, "Off label use ": 3.761269115147376, "Orthostatic hypotension ": 72.18348727811718, "Overdose ": 13.805918403104684, "Pain ": 2.840861513301707, "Product use in unapproved indication ": 10.42591707282712, "Renal function test abnormal ": 431.05760751341165, "Sedation ": 80.51341514140996, "Sedation complication ": 259.20720900875415, "Substance abuse ": 20.207577378223093, "Toxicity to various agents ": 10.85850513254288}
\ No newline at end of file
+{"Adrenal insufficiency": 9.045534272557177, "Ageusia": 2.0209829234739463, "Alanine aminotransferase increased": 3.040997025994717, "Amylase increased": 3.0569301310287527, "Anal fistula": 7.978759359470787, "Aortic dissection": 5.651180133242971, "Ascites": 3.794009366499808, "Aspartate aminotransferase increased": 3.6076785737540007, "Biliary obstruction": 6.744196152642999, "Blood albumin decreased": 3.549654054084169, "Blood calcium decreased": 3.8874940996650063, "Blood magnesium decreased": 4.088506210703563, "Blood pressure increased": 3.649456276985327, "Blood thyroid stimulating hormone increased": 11.05025827243693, "Bone lesion": 8.066637003611339, "Cancer pain": 27.415175844514145, "Cholangitis": 6.352951569570779, "Cholecystitis": 2.288890179426065, "Clear cell renal cell carcinoma": 21.10171661978338, "Colitis": 2.1686606160652278, "Constipation": 3.118954164521049, "Decreased appetite": 6.245478673078709, "Decubitus ulcer": 3.3643969707258976, "Dehydration": 2.6891990329668776, "Dermatitis acneiform": 5.1744747029107065, "Diarrhoea": 5.441923319435844, "Disease progression": 10.418643866634554, "Dry skin": 5.449332751267964, "Dysgeusia": 3.64204476711656, "Dysphonia": 6.048822483666789, "Enterocolitis": 2.9768280263463978, "Gastrointestinal perforation": 10.47796376931451, "Gastrointestinal toxicity": 5.031319210647889, "Haemophagocytic lymphohistiocytosis": 2.0354791878228404, "Hair colour changes": 23.051049143210896, "Hepatic cancer": 3.131920151152616, "Hepatic cytolysis": 2.5093329700202585, "Hepatic encephalopathy": 6.08890780555587, "Hepatic function abnormal": 7.710521979600127, "Hepatocellular carcinoma": 23.981351824918622, "Hepatotoxicity": 3.3430990204311355, "Hyperkeratosis": 13.130182007419895, "Hypertension": 5.9833245062476825, "Hyperthyroidism": 4.98235930642546, "Hypertransaminasaemia": 5.465354651768304, "Hypoalbuminaemia": 4.69309199306433, "Hypocalcaemia": 6.103868519239276, "Hypomagnesaemia": 7.626811251068116, "Hypothyroidism": 28.96376642823016, "Ileus": 2.12947533215046, "Immune-mediated enterocolitis": 4.611622776121585, "Immune-mediated hepatic disorder": 10.44435535647333, "Immune-mediated lung disease": 5.669339994370568, "Impaired healing": 4.975232848015149, "Inappropriate schedule of product administration": 3.3106557638967997, "Interstitial lung disease": 3.472650526694036, "Intestinal metastasis": 28.611981514126622, "Intestinal perforation": 5.225304838393497, "Intra-abdominal fluid collection": 12.83984879091715, "Large intestine perforation": 9.63845076714197, "Liver disorder": 6.029553093943282, "Liver function test increased": 3.3857095657905565, "Lumbar vertebral fracture": 4.972312336121661, "Lung opacity": 3.098085346602238, "Malignant neoplasm progression": 14.661974159717865, "Malignant pleural effusion": 13.3523608934262, "Metastases to adrenals": 12.397178295566626, "Metastases to bone": 16.25920264966424, "Metastases to central nervous system": 9.842122997169472, "Metastases to liver": 5.535941811701664, "Metastases to lung": 16.95571722064257, "Metastases to lymph nodes": 5.654454550740965, "Metastases to pancreas": 55.94663760548036, "Metastases to peritoneum": 5.542304053918134, "Metastases to spine": 12.99540661047675, "Metastasis": 2.8257224043979323, "Metastatic renal cell carcinoma": 14.59420405941105, "Mucosal inflammation": 11.87565139913368, "Nephrotic syndrome": 5.82799880222245, "Off label use": 2.0155810701562946, "Oral mucosal blistering": 2.29833029336413, "Oral pain": 4.215562769272423, "Osteonecrosis of jaw": 22.01998092004542, "Palmar-plantar erythrodysaesthesia syndrome": 62.657843755032495, "Performance status decreased": 3.67665349430877, "Peripheral ischaemia": 4.065562228898975, "Platelet count decreased": 3.06850746594017, "Pleural effusion": 2.428260033382291, "Pneumatosis intestinalis": 9.932560880168898, "Pneumonia aspiration": 2.0203078763028626, "Pneumonia bacterial": 3.593742789696394, "Pneumothorax": 2.5671816044202616, "Portal vein thrombosis": 4.837695702680964, "Posterior reversible encephalopathy syndrome": 4.378937685188248, "Product prescribing issue": 4.450954687311735, "Protein urine present": 12.793053284807993, "Proteinuria": 26.78536542414077, "Pulmonary embolism": 2.1370194049293185, "Pulmonary mass": 2.655555117196493, "Renal cancer": 4.804725309300088, "Renal cancer metastatic": 39.12781870906797, "Renal cell carcinoma": 63.29657073028297, "Renal cell carcinoma recurrent": 143.72010923692048, "Renal impairment": 2.650868334882258, "Skin disorder": 2.2744653408794, "Skin exfoliation": 2.4071750317231677, "Skin fissures": 2.5775962657538427, "Skin toxicity": 13.857098392532317, "Skin ulcer": 8.119764138962537, "Small intestinal perforation": 18.603948372029556, "Stomatitis": 12.119383627469611, "Taste disorder": 15.59055012721845, "Thyroid disorder": 6.2736237387698965, "Thyroid hormones increased": 19.10873231146001, "Thyroiditis": 9.303776191789808, "Tooth disorder": 3.4526729042316786, "Tumour haemorrhage": 8.39564204950474, "Tumour necrosis": 19.208303575720848, "Weight decreased": 4.018071666866069}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/223.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/223.json
index 5662b06cfa4..3658e4efd6a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/223.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/223.json
@@ -1 +1 @@
-{"Abdominal pain ": 5.518784455635757, "Blood pressure increased ": 10.683176443952298, "Completed suicide ": 34.59229557601386, "Drug interaction ": 6.50988286193747, "Drug intolerance ": 13.948528772249734, "Hypophagia ": 62.20750315514399, "Malignant neoplasm progression ": 9.729671495002776, "Renal impairment ": 11.760902851329568, "Toxicity to various agents ": 28.557720540389333}
\ No newline at end of file
+{"Blood HIV RNA increased": 190.6543567706349, "Depressed mood": 5.637464896256121, "Discomfort": 2.866000603044311, "Drug level decreased": 36.35144395263132, "Feeling hot": 2.3383451361351115, "Inappropriate schedule of product administration": 3.680133894439991, "Injection site nodule": 85.92336302585137, "Injection site pain": 10.948866588309198, "Injection site reaction": 4.015109574368509, "Injection site swelling": 2.1918420339120623, "Pain": 2.293782496247933, "Pathogen resistance": 183.76987592374437, "Suicidal ideation": 2.3865634086647702, "Treatment failure": 4.661414982408615, "Treatment noncompliance": 8.930505311324094, "Viral load increased": 207.0862112670229, "Viral mutation identified": 277.00556144659186, "Virologic failure": 307.8958115495183, "Wrong technique in product usage process": 5.283241630417883}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/224.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/224.json
index e87baa49c87..ba1ddc7fd0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/224.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/224.json
@@ -1 +1 @@
-{"Drug interaction ": 7.524376428884468}
\ No newline at end of file
+{"Diarrhoea": 2.720505748643145, "Hepatocellular carcinoma": 29.996389152386485, "Malignant neoplasm progression": 23.020014512618467, "Palmar-plantar erythrodysaesthesia syndrome": 27.602612950673223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/225.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/225.json
index 5336c97f907..8967b8c0815 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/225.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/225.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.8529307959035943, "Asthma ": 21.40505444473037, "Asthma-chronic obstructive pulmonary disease overlap syndrome ": 383.5234770406913, "Bronchiectasis ": 39.18518846424416, "Chronic obstructive pulmonary disease ": 6.230710300258888, "Deep vein thrombosis ": 3.876863225205865, "Depression ": 9.045427258831229, "Diabetes mellitus ": 25.52477491856165, "Diabetic ketoacidosis ": 29.23219617567595, "Euglycaemic diabetic ketoacidosis ": 78.75619550834354, "Full blood count abnormal ": 63.30852326924861, "Gastrooesophageal reflux disease ": 29.983030457329612, "Glycosylated haemoglobin increased ": 16.69390288220819, "Hallucination, auditory ": 31.4351166178976, "Hallucination, visual ": 19.81392393494083, "Hyperglycaemia ": 25.853280399146083, "Hypoacusis ": 27.64660658007411, "Hypoglycaemia ": 9.884787460127573, "Inappropriate schedule of product administration ": 2.8294218193359, "Ketoacidosis ": 34.979973407299255, "Lactic acidosis ": 7.561294628413499, "Loss of personal independence in daily activities ": 9.182070803183922, "Lung disorder ": 6.6244199844684335, "Metabolic acidosis ": 12.955663861865364, "Multiple allergies ": 82.72575419753434, "Mycobacterial infection ": 180.1345642652421, "Obesity ": 19.6982147703357, "Obstructive airways disorder ": 16.508213335505754, "Product prescribing error ": 30.022121513609054, "Productive cough ": 7.393231004927482, "Psychotic disorder ": 16.020176613031254, "Pulmonary embolism ": 2.424857553112984, "Renal impairment ": 2.391776707525742, "Respiratory failure ": 4.26297639439913, "Sleep disorder due to a general medical condition ": 50.41984522865183, "Suicidal ideation ": 5.303744612705502, "Type 2 diabetes mellitus ": 85.63184190946521, "Wheezing ": 13.058257671473092}
\ No newline at end of file
+{"Acute myeloid leukaemia": 16.416231902655245, "Anaemia": 2.665708319608646, "Anaphylactic reaction": 3.154237107480918, "Anaphylactic shock": 2.5660765514582184, "Anaphylactoid reaction": 5.894912179903048, "Aphthous ulcer": 2.2152020209205, "Ascites": 4.495874422105774, "Back pain": 4.11807273787603, "Blood alkaline phosphatase increased": 2.0265810399343835, "Brain oedema": 2.2878285002293035, "Breast cancer metastatic": 13.844215625537611, "Bronchospasm": 6.762408595565901, "Candida infection": 2.6094743054828635, "Cardiogenic shock": 2.455242648088, "Cardiotoxicity": 20.606775732460548, "Cerebral toxoplasmosis": 51.55851123437852, "Chest discomfort": 2.7023220319057613, "Cyanosis": 3.905814382529029, "Dermatitis": 3.721657791427838, "Dermatitis bullous": 6.755571905295695, "Dermatitis exfoliative generalised": 2.9702628391934014, "Desmoplastic small round cell tumour": 354.2972950340737, "Diffuse large B-cell lymphoma": 14.31536208390516, "Diffuse large B-cell lymphoma recurrent": 20.610196016135923, "Diffuse large B-cell lymphoma refractory": 103.41626631044566, "Dilated cardiomyopathy": 6.819344488332185, "Disease progression": 6.799625397537933, "Dysgraphia": 6.83519294491055, "Ejection fraction decreased": 5.790505029138122, "Epstein-Barr virus infection": 8.937936264537738, "Erythema": 4.7065028340627375, "Extravasation": 24.702306206251336, "Febrile neutropenia": 8.438589942503333, "Feeling hot": 2.12627571503587, "Flushing": 12.435846694801675, "Gastric ulcer": 3.120830111855331, "Haematotoxicity": 12.74634902097489, "Haemorrhage intracranial": 2.6532110974691308, "Hepatitis cholestatic": 2.79778209103456, "Hepatotoxicity": 3.693891311750168, "Hypersensitivity": 4.083071907326811, "Hypertransaminasaemia": 2.337656610588982, "Hypoxia": 2.9732175357673745, "Infusion related reaction": 27.69827858036788, "Infusion site reaction": 16.34110469836217, "Interstitial lung disease": 14.952238530596354, "Intestinal obstruction": 4.048924344642032, "Laryngeal oedema": 4.306993799886247, "Leukopenia": 4.093935420241425, "Malignant neoplasm progression": 3.0948885531340853, "Mantle cell lymphoma recurrent": 129.70878503950638, "Metastases to bone": 3.441742769172808, "Metastases to liver": 7.25386423540664, "Metastases to lymph nodes": 9.765847469944289, "Metastases to peritoneum": 32.53880288847138, "Mouth ulceration": 2.9870909385078663, "Mucosal inflammation": 16.872895737343462, "Multiple-drug resistance": 7.648590483363011, "Myelodysplastic syndrome": 6.218518014670228, "Neoplasm progression": 6.484491072544475, "Neurological symptom": 3.571900301581749, "Neuropathy peripheral": 2.499008906285162, "Neurotoxicity": 2.080584492222345, "Neutropenia": 7.356037501308275, "Neutropenic sepsis": 9.34679140187509, "Neutrophil count increased": 4.85518163478879, "Off label use": 6.632555329667047, "Ovarian cancer": 27.03620824413983, "Palmar-plantar erythrodysaesthesia syndrome": 58.44418964901055, "Pancytopenia": 5.75086480447691, "Plasma cell myeloma": 6.550785786912292, "Plasma cell myeloma recurrent": 21.28066622512318, "Pneumonitis": 2.416346374017764, "Polyneuropathy": 4.035874746464884, "Post transplant lymphoproliferative disorder": 20.86388934609301, "Product use in unapproved indication": 15.357298762361864, "Progressive multifocal leukoencephalopathy": 11.182075505572945, "Second primary malignancy": 3.849320436811404, "Sense of oppression": 11.278713760496354, "Sepsis": 2.761768953368004, "Serous cystadenocarcinoma ovary": 699.3842590766859, "Skin exfoliation": 3.4631216770196502, "Skin hyperpigmentation": 9.01758605148926, "Skin lesion": 2.308551366460995, "Skin reaction": 4.8504101124817645, "Skin toxicity": 23.488090680243136, "Skin ulcer": 3.1359534856752225, "Smooth muscle cell neoplasm": 191.984106825042, "Stomatitis": 7.331746732032793, "Throat tightness": 2.1973748271421694, "Thrombocytopenia": 3.5205231337249354, "Toxic epidermal necrolysis": 2.360747061845563, "Toxic skin eruption": 7.479793148253372, "Transaminases increased": 2.8787783426659894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/226.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/226.json
index ad7848aa2e3..d0679956daf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/226.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/226.json
@@ -1 +1 @@
-{"Cellulitis ": 27.599986625047823, "Condition aggravated ": 6.664073304317863, "Drug ineffective ": 2.2202567406657847, "Gastrointestinal haemorrhage ": 5.74002712676863, "Growth retardation ": 397.05889983740735, "Muscle abscess ": 1507.303276494352, "Osteoporosis ": 10.236979833369356, "Pneumonia streptococcal ": 1284.7406007768789, "Product use in unapproved indication ": 9.81835041445614, "Secondary adrenocortical insufficiency ": 471.6832882559841, "Staphylococcal infection ": 46.722405571583664, "X-linked lymphoproliferative syndrome ": 39948.25834000792}
\ No newline at end of file
+{"Balance disorder": 24.5753568888814, "Blood calcium decreased": 189.47457383055595, "Cognitive disorder": 47.04701700739756, "Constipation": 12.35139713373563, "Creatinine renal clearance decreased": 239.34372577795668, "Creatinine renal clearance increased": 1702.9612475917645, "Depressed level of consciousness": 31.955032084904374, "Drug abuse": 25.059676152125206, "Drug dependence": 6.506951319547394, "Drug interaction": 8.572566116896256, "Dyspnoea": 2.482587798841336, "Fall": 8.56926891762145, "Hypotension": 7.72790329796839, "Irritability": 6.625733662931749, "Mobility decreased": 30.252681634466477, "Multiple drug therapy": 1276.726816297091, "Off label use": 3.7611209592063752, "Orthostatic hypotension": 72.16789959699128, "Overdose": 13.805918403104684, "Pain": 2.840837364490705, "Product use in unapproved indication": 10.425591825072408, "Renal function test abnormal": 431.05760751341165, "Sedation": 80.51341514140996, "Sedation complication": 259.20720900875415, "Substance abuse": 20.207577378223093, "Toxicity to various agents": 10.85850513254288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/227.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/227.json
index c13142d5a16..b467a2e4e77 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/227.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/227.json
@@ -1 +1 @@
-{"Acidosis ": 5.918102830647242, "Acquired haemophilia ": 36.188647529063, "Acute generalised exanthematous pustulosis ": 10.534539441437744, "Acute graft versus host disease ": 8.887920002633583, "Acute graft versus host disease in intestine ": 28.6298501178443, "Acute hepatic failure ": 3.8503781547884985, "Acute kidney injury ": 3.5593149057292037, "Acute myeloid leukaemia ": 10.760892781397724, "Acute respiratory distress syndrome ": 5.166730857925002, "Acute respiratory failure ": 4.904692316666604, "Adverse event ": 2.683168765401404, "Agranulocytosis ": 5.870420614198936, "Alanine aminotransferase increased ": 7.5257957914691165, "Altered state of consciousness ": 2.175993581873835, "Aspartate aminotransferase increased ": 8.136862780168219, "Aspergillus infection ": 36.52320069456084, "Bacterial infection ": 9.865618960501134, "Bilirubin conjugated increased ": 14.859991202012823, "Blood alkaline phosphatase increased ": 13.713780090403658, "Blood bilirubin increased ": 6.821098364381569, "Blood lactate dehydrogenase increased ": 10.262490026935035, "Blood potassium decreased ": 3.486112984420863, "Bone marrow failure ": 4.097566214806905, "Bronchopulmonary aspergillosis ": 43.34668494295642, "Bronchospasm ": 3.6155505404586346, "C-reactive protein increased ": 4.135054817194091, "Candida infection ": 9.611115186967746, "Cell death ": 18.21437716595152, "Central nervous system fungal infection ": 362.8002460586913, "Cholestasis ": 17.967073155052127, "Death ": 3.3784343330732667, "Delirium ": 3.3458247726527013, "Dermatitis exfoliative generalised ": 13.350111919498111, "Diffuse large B-cell lymphoma refractory ": 163.16228952500327, "Disseminated intravascular coagulation ": 6.955663025089515, "Drug ineffective ": 2.9334386639803647, "Drug level increased ": 4.169222468464975, "Drug reaction with eosinophilia and systemic symptoms ": 14.97689525110187, "Drug resistance ": 12.67587317565221, "Drug-induced liver injury ": 6.379175637768167, "Encephalopathy ": 5.113379632810168, "Enterocolitis ": 7.639021283501832, "Eosinophilia ": 7.270462614918485, "Eschar ": 110.59922593877658, "Febrile neutropenia ": 3.305773377064434, "Fungaemia ": 100.61353957184764, "Fungal infection ": 19.84928634932561, "Fungal skin infection ": 34.02599070962757, "Gamma-glutamyltransferase increased ": 9.246756972660862, "Graft versus host disease ": 7.090237349909074, "Graft versus host disease in gastrointestinal tract ": 37.73632313185117, "Haematuria ": 2.5261554531428003, "Haemophagocytic lymphohistiocytosis ": 5.224009958049547, "Haemoptysis ": 2.0902331337684217, "Hepatic cytolysis ": 10.427131539869697, "Hepatic enzyme increased ": 3.208059300340692, "Hepatic failure ": 7.318640578884482, "Hepatic function abnormal ": 8.582483043645569, "Hepatitis ": 2.1209667609712053, "Hepatitis cholestatic ": 5.708432239383474, "Hepatitis fulminant ": 21.26528082258209, "Hepatocellular injury ": 8.8907234308636, "Hepatotoxicity ": 2.823826544931943, "Hyperbilirubinaemia ": 15.619777262057577, "Hypercalcaemia ": 6.249907200072996, "Hyperthermia ": 5.335012905184868, "Hypokalaemia ": 12.372192338058692, "Hypomagnesaemia ": 10.672039843379068, "Incorrect dose administered ": 2.364643035261509, "Jaundice ": 2.147810521158517, "Leukopenia ": 4.744077546766662, "Liver disorder ": 4.661810132107933, "Liver function test abnormal ": 3.136483807733892, "Liver injury ": 4.526709125891083, "Lymphoma ": 5.136868806508928, "Mucosal erosion ": 49.072009640340674, "Multiple organ dysfunction syndrome ": 18.17512832966768, "Myoclonus ": 6.859555454295205, "Neoplasm progression ": 3.3264228941321394, "Nephropathy toxic ": 3.8669372898050254, "Neutropenia ": 2.234345506582324, "Neutrophil count decreased ": 4.241443562328434, "Neutrophil count increased ": 24.08427274796544, "Oedema ": 2.1624607701070646, "Organ failure ": 40.14281119641697, "Pancreatitis ": 3.386882733663956, "Pancreatitis acute ": 2.73345514031356, "Pancytopenia ": 4.565684632829624, "Pathogen resistance ": 11.889853253028583, "Platelet count decreased ": 2.283673216170984, "Pneumonia ": 2.2780386140847813, "Pneumonia bacterial ": 6.20480848018251, "Prescribed overdose ": 2.001241869493409, "Pulmonary alveolar haemorrhage ": 7.533468878919313, "Purpura ": 3.0718095777952747, "Rash maculo-papular ": 14.904908925870142, "Rash morbilliform ": 6.611616611287412, "Renal impairment ": 2.298178094383299, "Respiratory distress ": 2.1981751754294296, "Respiratory failure ": 5.654031228969099, "Sepsis ": 4.566229930162988, "Septic shock ": 13.71752807117186, "Sinus bradycardia ": 3.865508742399375, "Skin erosion ": 18.629311331140155, "Skin lesion ": 4.224056028500778, "Staphylococcal infection ": 2.243105678053489, "Staphylococcal sepsis ": 12.7876201157994, "Stevens-Johnson syndrome ": 6.4233581175141, "Systemic candida ": 44.726845426116746, "Systemic mycosis ": 88.36836651328377, "Therapy non-responder ": 2.252243678069898, "Thrombocytopenia ": 5.315123722826751, "Toxic encephalopathy ": 9.512090790117238, "Toxic epidermal necrolysis ": 17.44600546216288, "Toxic skin eruption ": 19.13423348005566, "Transaminases increased ": 5.5955777393867, "White blood cell count decreased ": 3.100931658773742, "White blood cell count increased ": 7.748932073997253}
\ No newline at end of file
+{"Abdominal pain": 5.518784455635757, "Blood pressure increased": 10.682988950308037, "Completed suicide": 34.59229557601386, "Drug interaction": 6.50988286193747, "Drug intolerance": 13.948528772249734, "Hypophagia": 62.20750315514399, "Malignant neoplasm progression": 9.729671495002776, "Renal impairment": 11.760902851329568, "Toxicity to various agents": 28.557720540389333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/228.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/228.json
index fd89ea17219..6537a8934c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/228.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/228.json
@@ -1 +1 @@
-{"Hypotension ": 24.662597546329067}
\ No newline at end of file
+{"Drug interaction": 7.105508462049342}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/229.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/229.json
index dae2acb7795..c1670398ecc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/229.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/229.json
@@ -1 +1 @@
-{"Aggression ": 4.859331363345334, "Agitation ": 7.049334037155823, "Amnesia ": 4.44433280579396, "Arthritis ": 3.9038755677663466, "Balance disorder ": 2.4363098382793997, "Basal ganglia stroke ": 1279.3293503412715, "Behaviour disorder ": 115.3863953710028, "Carotid artery stenosis ": 58.28750891002685, "Cerebral infarction ": 5.447597248538198, "Cholestasis ": 4.561354074717738, "Cognitive disorder ": 5.429828504700485, "Condition aggravated ": 2.429682633592164, "Confusional state ": 2.5346209226252983, "Cystic fibrosis ": 92.85989836104471, "Depression ": 2.024009624465931, "Disinhibition ": 46.48321769964711, "Drug abuse ": 17.285453545261063, "Drug dependence ": 6.837390555835788, "Drug ineffective for unapproved indication ": 4.169940626284627, "Drug interaction ": 10.235501168424896, "Drug level increased ": 22.37793394794624, "Drug resistance ": 2.517949753545401, "Dysarthria ": 4.220369824274967, "Dyskinesia ": 2.270507392317191, "Epilepsy ": 7.822489278520348, "Facial paralysis ": 6.029554301778748, "Fibromyalgia ": 8.89091662842922, "Hepatic enzyme increased ": 2.034996503835309, "Hepatitis ": 2.665927530092933, "Hypersexuality ": 88.82331307979784, "Intervertebral disc protrusion ": 18.95311135418196, "Lethargy ": 4.37397642326073, "Leukocytosis ": 5.210673312692011, "Liver function test abnormal ": 4.77127703389505, "Malignant cranial nerve neoplasm ": 6173.011979038408, "Metal poisoning ": 132.0096209278199, "Metastases to liver ": 4.847550654733778, "Metastases to spine ": 37.158299060983616, "Multiple-drug resistance ": 261.95180239719457, "Nerve compression ": 22.40117854522213, "Neuroblastoma recurrent ": 545.5897569526122, "Off label use ": 3.039159894896567, "Osteoarthritis ": 6.11201945184307, "Ovarian cyst ": 18.36312986808593, "Pallor ": 3.392398640244805, "Panic attack ": 3.5010844484843004, "Petit mal epilepsy ": 11.787846729550232, "Poisoning ": 9.56235383226558, "Psychotic disorder ": 8.818956485500166, "Restlessness ": 3.7255688331177415, "Retro-orbital neoplasm ": 2835.8261528496346, "Scar pain ": 228.33166332942892, "Sedation ": 9.526209467297024, "Seizure ": 6.881879532932979, "Serotonin syndrome ": 6.00236011520579, "Skin reaction ": 8.68376266470596, "Somnolence ": 3.6130702012466345, "Status epilepticus ": 11.094669733373134, "Stress ": 2.7654569226944017, "Substance abuse ": 7.623263944840117, "Substance use disorder ": 89.64153421599345, "Withdrawal syndrome ": 3.01035476977939}
\ No newline at end of file
+{"Acute kidney injury": 2.849112642334623, "Asthma": 21.376322141249872, "Asthma-chronic obstructive pulmonary disease overlap syndrome": 383.0106498809373, "Bronchiectasis": 39.132790058294525, "Chronic obstructive pulmonary disease": 6.2223785669884215, "Deep vein thrombosis": 3.871678560725496, "Depression": 9.033302388730371, "Diabetes mellitus": 25.49056394780827, "Diabetic ketoacidosis": 29.193034745197984, "Euglycaemic diabetic ketoacidosis": 78.65079508481217, "Full blood count abnormal": 63.22364631229287, "Gastrooesophageal reflux disease": 29.942832323206527, "Glycosylated haemoglobin increased": 16.67157348414034, "Hallucination, auditory": 31.393055824025748, "Hallucination, visual": 19.78741248109205, "Hyperglycaemia": 25.818614097497424, "Hypoacusis": 27.607263052420763, "Hypoglycaemia": 9.871205438828682, "Inappropriate schedule of product administration": 2.8256379343291727, "Ketoacidosis": 34.93317325695415, "Lactic acidosis": 7.551182649665888, "Loss of personal independence in daily activities": 9.169782203026308, "Lung disorder": 6.615561781279364, "Metabolic acidosis": 12.938334642287456, "Multiple allergies": 82.61513393612219, "Mycobacterial infection": 179.8936923686781, "Obesity": 19.671874272019515, "Obstructive airways disorder": 16.486138506290654, "Product prescribing error": 29.981951327051757, "Productive cough": 7.383344745186011, "Psychotic disorder": 15.998741263512816, "Pulmonary embolism": 2.421615021470094, "Renal impairment": 2.3885784117426323, "Respiratory failure": 4.256924448185231, "Sleep disorder due to a general medical condition": 50.35233553209088, "Suicidal ideation": 5.296648075466706, "Type 2 diabetes mellitus": 85.5170368402329, "Wheezing": 13.040254279569876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/23.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/23.json
index 67934413aa0..59b82c47617 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/23.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/23.json
@@ -1 +1 @@
-{"Blood glucose decreased ": 13.51894874585776, "Blood glucose increased ": 26.998733641471016, "Cold sweat ": 16.90067023250686, "Hyperhidrosis ": 3.458195749106008, "Hypoglycaemia ": 55.76034105879474, "Hypoglycaemic coma ": 170.29349442168697, "Liquid product physical issue ": 146.44913670522578, "Loss of consciousness ": 6.761780926959728, "Shock hypoglycaemic ": 779.2051217499967}
\ No newline at end of file
+{"Acute generalised exanthematous pustulosis": 8.910389548435349, "Acute kidney injury": 2.1916074259147784, "Acute myocardial infarction": 3.4883791970158367, "Alanine aminotransferase increased": 3.3897976435630683, "Altered state of consciousness": 6.028416208279905, "Aspartate aminotransferase increased": 3.0320271274442865, "Bladder cancer": 23.634531436107697, "Blood alkaline phosphatase increased": 2.145073842746214, "Blood creatine phosphokinase increased": 2.283887913617481, "Blood glucose decreased": 9.871303501438664, "Blood glucose fluctuation": 4.7917306369997466, "Blood glucose increased": 6.529147835667302, "Blood lactate dehydrogenase increased": 2.7903965803440096, "Blood potassium decreased": 3.0936523112478187, "Blood urea increased": 2.7035756497241588, "Cardiac failure": 3.259655646444917, "Cardiac failure congestive": 9.663846120743306, "Cardiomegaly": 11.784102431181612, "Cataract": 6.79042574734636, "Cold sweat": 3.239288111467045, "Coronary artery disease": 7.204074925916214, "Dehydration": 2.0211982873275063, "Depressed level of consciousness": 3.031350733338953, "Diabetes mellitus inadequate control": 10.31135478235812, "Diabetic ketoacidosis": 9.56926879566681, "Drug interaction": 3.013036172458735, "Fluid retention": 9.471146950425307, "Gamma-glutamyltransferase increased": 4.157908084253837, "Gastrooesophageal reflux disease": 2.4197457214023403, "Glycosylated haemoglobin increased": 10.487066583468224, "Haemoptysis": 2.2800641442735667, "Hepatic cirrhosis": 4.166404044301671, "Hepatic failure": 3.315944750371807, "Hepatic function abnormal": 3.043681227231443, "Hepatic steatosis": 4.235496209895322, "Hiatus hernia": 6.220564909652137, "Hyperglycaemia": 2.503170381466811, "Hypoglycaemia": 19.157579612427885, "Hypoglycaemic coma": 12.831146775899136, "Incorrect dose administered": 2.119561135876678, "Interstitial lung disease": 2.413436957642366, "Irritable bowel syndrome": 5.016586896530147, "Lactic acidosis": 3.957634221793165, "Left ventricular hypertrophy": 14.489749653736553, "Liver disorder": 3.54714053290103, "Liver injury": 4.948282474913838, "Macular oedema": 13.12038077838579, "Medication error": 4.339307089340261, "Mental impairment": 3.007437960436293, "Metabolic acidosis": 2.6123337144185106, "Multiple allergies": 34.292948131753434, "Myocardial infarction": 3.595675451737431, "Non-cardiac chest pain": 35.87334095451814, "Oedema": 4.9641528571071785, "Oedema peripheral": 3.8441571869685536, "Pancreatic carcinoma": 3.0423712227496096, "Pancreatitis": 2.0136805132463795, "Pleural effusion": 2.0961143596819154, "Pulmonary oedema": 5.1786890260967535, "Reflux gastritis": 43.2603399575675, "Rhabdomyolysis": 2.356739891110976, "Skin ulcer": 2.887453476442814, "Treatment noncompliance": 3.1324572071926275, "Urinary incontinence": 2.761196356022644, "Urine output decreased": 9.784746227075605, "Weight increased": 6.644666008582862}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/230.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/230.json
index a4d88f079a2..3d7c516dda5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/230.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/230.json
@@ -1 +1 @@
-{"Toxicity to various agents ": 16.95599428910996}
\ No newline at end of file
+{"Cellulitis": 27.599986625047823, "Condition aggravated": 6.664073304317863, "Drug ineffective": 2.220240328480463, "Gastrointestinal haemorrhage": 5.74002712676863, "Growth retardation": 397.05889983740735, "Muscle abscess": 1507.303276494352, "Osteoporosis": 10.236979833369356, "Pneumonia streptococcal": 1284.7406007768789, "Product use in unapproved indication": 9.818044199080132, "Secondary adrenocortical insufficiency": 471.6832882559841, "Staphylococcal infection": 46.722405571583664, "X-linked lymphoproliferative syndrome": 39948.25834000792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/231.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/231.json
index 340207e0d11..3a65a7da3f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/231.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/231.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 3.0280353143031533, "Adenocarcinoma ": 12.117343663239335, "Anaemia ": 2.2424154727298973, "Arteriospasm coronary ": 12.216730301039656, "Ascites ": 3.8488747112519217, "Bacteraemia ": 2.236781853131563, "Blood albumin decreased ": 3.430520576154891, "Blood iron decreased ": 2.862059606200239, "Blood magnesium decreased ": 8.340903484805855, "Blood pressure diastolic decreased ": 3.81934977638114, "Blood pressure systolic decreased ": 3.3573072669339576, "Bone lesion ": 16.51210738481975, "Breast cancer ": 6.423818021981213, "Breast cancer metastatic ": 33.63844507578386, "Breast cancer recurrent ": 27.46717806307184, "Breast disorder ": 15.766508143965282, "Cachexia ": 3.5900340812922424, "Carcinoembryonic antigen increased ": 14.10424306208571, "Cardiogenic shock ": 2.4753862472502237, "Cardiotoxicity ": 27.9252384050195, "Colitis ": 2.0153161900268204, "Colon cancer metastatic ": 18.17424934227769, "Colorectal cancer metastatic ": 16.005697177598748, "Cytopenia ": 5.324886618842485, "Diarrhoea ": 3.447174332154427, "Dihydropyrimidine dehydrogenase deficiency ": 182.57259841240776, "Disease progression ": 8.677030110612389, "Disease recurrence ": 2.9929378388307533, "Drug intolerance ": 2.950623862903716, "Drug-induced liver injury ": 3.481188986492185, "Ejection fraction decreased ": 4.319186885059996, "Electrolyte imbalance ": 5.072774054331535, "Enteritis ": 11.84032310285785, "Enterocolitis ": 5.486842003799529, "Faeces soft ": 3.643732549835821, "Febrile neutropenia ": 2.517304199184345, "Foetal growth restriction ": 2.512012889658638, "Gastrointestinal toxicity ": 25.20598162039343, "Gingival pain ": 2.724534529343244, "Granulocyte count decreased ": 7.505568839924707, "Granulocytopenia ": 5.69076160390638, "Groin pain ": 2.198956081251413, "Haematotoxicity ": 15.038631744374356, "Hand dermatitis ": 19.68713291527521, "Hepatic lesion ": 10.802799056407746, "Hepatotoxicity ": 4.88377091229686, "Hiccups ": 3.80699673623874, "Hyperammonaemic encephalopathy ": 6.329818278832468, "Hyperbilirubinaemia ": 2.616640240943848, "Hypercholesterolaemia ": 4.311590540912288, "Hypertransaminasaemia ": 3.922400271374701, "Hypoalbuminaemia ": 3.0858001529035177, "Hypokalaemia ": 2.2286791241588912, "Ileus ": 2.1972984756670977, "Immunosuppression ": 6.894928108034862, "Invasive ductal breast carcinoma ": 12.296788550554282, "Lacrimation increased ": 2.599719125318074, "Laryngospasm ": 6.490139241070271, "Left ventricular dysfunction ": 5.894981229938773, "Leukopenia ": 4.482413000593519, "Liver injury ": 2.124449539747236, "Lymphangiosis carcinomatosa ": 15.400149136561572, "Malignant neoplasm progression ": 12.50883496228145, "Metastases to bone ": 37.54396653800693, "Metastases to central nervous system ": 23.31138394386436, "Metastases to eye ": 86.46264186745579, "Metastases to liver ": 35.235771579763714, "Metastases to lung ": 20.936748260534216, "Metastases to lymph nodes ": 28.009540242665626, "Metastases to meninges ": 16.4393439860207, "Metastases to peritoneum ": 14.38048008724238, "Metastases to skin ": 72.23905247420778, "Metastases to spine ": 17.80566651191498, "Metastases to the mediastinum ": 47.4411592404888, "Metastasis ": 8.742747202471499, "Metastatic neoplasm ": 9.325335904707348, "Mucosal inflammation ": 12.20438660192316, "Myelodysplastic syndrome ": 4.524067430787326, "Myelosuppression ": 28.43857497139052, "Myositis ": 2.662009030050384, "Nail disorder ": 5.124982319852399, "Neoplasm progression ": 4.231867734352878, "Neuropathy peripheral ": 9.213669610811804, "Neurotoxicity ": 12.135852915879894, "Neutropenia ": 8.342434124923704, "Neutrophil count decreased ": 7.933050834892691, "Oesophagitis ": 2.9485847260199187, "Osteolysis ": 16.195629681325563, "Osteonecrosis of jaw ": 4.17964592395439, "PIK3CA-activated mutation ": 125.74100353664238, "Palmar-plantar erythrodysaesthesia syndrome ": 18.791413504171032, "Pancreatic neuroendocrine tumour ": 29.616446771874728, "Pancreatic neuroendocrine tumour metastatic ": 46.18776361163071, "Pancytopenia ": 2.6676738068405887, "Peripheral sensory neuropathy ": 7.494455365201925, "Platelet count decreased ": 6.947429745418879, "Pneumonitis ": 3.553683386549746, "Polyneuropathy ": 5.283650277506104, "Portal hypertension ": 7.229159722415427, "Posterior reversible encephalopathy syndrome ": 3.1194627140444022, "Product use in unapproved indication ": 2.5833030548062683, "Protein total increased ": 13.209624266290229, "Pulmonary mass ": 4.236376950585338, "Recall phenomenon ": 50.37698390250745, "Recurrent cancer ": 35.73464891570601, "Seasonal allergy ": 2.6089002840507303, "Second primary malignancy ": 2.5380330630428176, "Skin fissures ": 7.53154859761381, "Skin mass ": 3.165823093519471, "Skin toxicity ": 12.867081080569804, "Stomatitis ": 2.878715761421417, "Therapy partial responder ": 9.615163808295044, "Thrombocytopenia ": 6.182142113287272, "Tumour marker increased ": 20.820287401022053, "Venoocclusive liver disease ": 8.272241757917357, "Vulvovaginal pain ": 7.722920801418919, "White blood cell count decreased ": 6.321392784495624}
\ No newline at end of file
+{"Acidosis": 5.918102830647242, "Acquired haemophilia": 36.188647529063, "Acute generalised exanthematous pustulosis": 10.534539441437744, "Acute graft versus host disease": 8.887920002633583, "Acute graft versus host disease in intestine": 28.6298501178443, "Acute hepatic failure": 3.8503781547884985, "Acute kidney injury": 3.5593149057292037, "Acute myeloid leukaemia": 10.760892781397724, "Acute respiratory distress syndrome": 5.166730857925002, "Acute respiratory failure": 4.904692316666604, "Adverse event": 2.683168765401404, "Agranulocytosis": 5.870420614198936, "Alanine aminotransferase increased": 7.5257957914691165, "Altered state of consciousness": 2.175993581873835, "Aspartate aminotransferase increased": 8.136862780168219, "Aspergillus infection": 36.52320069456084, "Bacterial infection": 9.865618960501134, "Bilirubin conjugated increased": 14.859991202012823, "Blood alkaline phosphatase increased": 13.713780090403658, "Blood bilirubin increased": 6.821098364381569, "Blood lactate dehydrogenase increased": 10.262490026935035, "Blood potassium decreased": 3.486112984420863, "Bone marrow failure": 4.097566214806905, "Bronchopulmonary aspergillosis": 43.34668494295642, "Bronchospasm": 3.6155505404586346, "C-reactive protein increased": 4.135054817194091, "Candida infection": 9.611115186967746, "Cell death": 18.21437716595152, "Central nervous system fungal infection": 362.8002460586913, "Cholestasis": 17.967073155052127, "Death": 3.3784343330732667, "Delirium": 3.3458247726527013, "Dermatitis exfoliative generalised": 13.350111919498111, "Diffuse large B-cell lymphoma refractory": 163.16228952500327, "Disseminated intravascular coagulation": 6.955663025089515, "Drug ineffective": 2.9334169599547337, "Drug level increased": 4.169222468464975, "Drug reaction with eosinophilia and systemic symptoms": 14.975652601815009, "Drug resistance": 12.67587317565221, "Drug-induced liver injury": 6.378786131298563, "Encephalopathy": 5.113379632810168, "Enterocolitis": 7.639021283501832, "Eosinophilia": 7.270462614918485, "Eschar": 110.59922593877658, "Febrile neutropenia": 3.305773377064434, "Fungaemia": 100.61353957184764, "Fungal infection": 19.843744589406505, "Fungal skin infection": 34.02599070962757, "Gamma-glutamyltransferase increased": 9.246756972660862, "Graft versus host disease": 7.090237349909074, "Graft versus host disease in gastrointestinal tract": 37.73632313185117, "Haematuria": 2.5261554531428003, "Haemophagocytic lymphohistiocytosis": 5.224009958049547, "Haemoptysis": 2.0902331337684217, "Hepatic cytolysis": 10.427131539869697, "Hepatic enzyme increased": 3.208059300340692, "Hepatic failure": 7.318640578884482, "Hepatic function abnormal": 8.582483043645569, "Hepatitis": 2.1209667609712053, "Hepatitis cholestatic": 5.708432239383474, "Hepatitis fulminant": 21.26528082258209, "Hepatocellular injury": 8.888129809789534, "Hepatotoxicity": 2.823826544931943, "Hyperbilirubinaemia": 15.619777262057577, "Hypercalcaemia": 6.249907200072996, "Hyperthermia": 5.335012905184868, "Hypokalaemia": 12.372192338058692, "Hypomagnesaemia": 10.672039843379068, "Incorrect dose administered": 2.364643035261509, "Jaundice": 2.147810521158517, "Leukopenia": 4.743478731188167, "Liver disorder": 4.661810132107933, "Liver function test abnormal": 3.136483807733892, "Liver injury": 4.526709125891083, "Lymphoma": 5.136868806508928, "Mucosal erosion": 49.072009640340674, "Multiple organ dysfunction syndrome": 18.17512832966768, "Myoclonus": 6.859555454295205, "Neoplasm progression": 3.3264228941321394, "Nephropathy toxic": 3.8669372898050254, "Neutropenia": 2.234249369682727, "Neutrophil count decreased": 4.241443562328434, "Neutrophil count increased": 24.08427274796544, "Oedema": 2.1624607701070646, "Organ failure": 40.14281119641697, "Pancreatitis": 3.386882733663956, "Pancreatitis acute": 2.73345514031356, "Pancytopenia": 4.565684632829624, "Pathogen resistance": 11.889853253028583, "Platelet count decreased": 2.283673216170984, "Pneumonia": 2.2780386140847813, "Pneumonia bacterial": 6.20480848018251, "Prescribed overdose": 2.001241869493409, "Pulmonary alveolar haemorrhage": 7.533468878919313, "Purpura": 3.0718095777952747, "Rash maculo-papular": 14.904908925870142, "Rash morbilliform": 6.611616611287412, "Renal impairment": 2.298178094383299, "Respiratory distress": 2.1981751754294296, "Respiratory failure": 5.653563633267799, "Sepsis": 4.566229930162988, "Septic shock": 13.71752807117186, "Sinus bradycardia": 3.865508742399375, "Skin erosion": 18.629311331140155, "Skin lesion": 4.224056028500778, "Staphylococcal infection": 2.243105678053489, "Staphylococcal sepsis": 12.7876201157994, "Stevens-Johnson syndrome": 6.4233581175141, "Systemic candida": 44.726845426116746, "Systemic mycosis": 88.36836651328377, "Therapy non-responder": 2.252046866741633, "Thrombocytopenia": 5.314622910689248, "Toxic encephalopathy": 9.512090790117238, "Toxic epidermal necrolysis": 17.44600546216288, "Toxic skin eruption": 19.13423348005566, "Transaminases increased": 5.595234541009898, "White blood cell count decreased": 3.100931658773742, "White blood cell count increased": 7.747444881457829}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/232.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/232.json
index 082bc565f97..e98496b5250 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/232.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/232.json
@@ -1 +1 @@
-{"Acne ": 27.746559207382862, "Blood calcitonin increased ": 2023.5237525885243, "Blood calcium decreased ": 16.183524073014254, "Blood pressure increased ": 2.573533810819655, "Blood thyroid stimulating hormone increased ": 18.479056598280355, "Carcinoembryonic antigen increased ": 73.06501686625204, "Dehydration ": 2.156403652185406, "Diarrhoea ": 4.9485657453956255, "Disease progression ": 6.099002914542631, "Dry skin ": 9.078980022181668, "Electrocardiogram QT prolonged ": 42.41802507870104, "Hospitalisation ": 7.2893515022466335, "Hypertension ": 3.246513604072756, "Hypocalcaemia ": 13.812540258386909, "Malignant neoplasm progression ": 2.1683079265871723, "Neoplasm progression ": 3.644448726396821, "Photosensitivity reaction ": 20.36682090496372, "Rash ": 2.633323179765928, "Skin exfoliation ": 5.543495736990219}
\ No newline at end of file
+{"Hypotension": 24.66202745363512}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/233.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/233.json
index 94007093697..71db6b06267 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/233.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/233.json
@@ -1 +1 @@
-{"Constipation ": 3.1145794788476486, "Drug ineffective ": 4.613775495929782, "Immune thrombocytopenia ": 220.03782577967883, "Impaired quality of life ": 236.64416130164483, "Impaired work ability ": 64.17147643935897, "Loss of personal independence in daily activities ": 9.354370405041324, "Muscle spasms ": 3.6305471763679775, "Poor quality sleep ": 81.46797197332828, "Product use in unapproved indication ": 5.170875810685633, "Suicidal ideation ": 6.526078845143178, "Therapy non-responder ": 153.36883556698533, "Weight increased ": 22.949900014465992, "Withdrawal syndrome ": 17.252122727912}
\ No newline at end of file
+{"Aggression": 4.859331363345334, "Agitation": 7.049334037155823, "Amnesia": 4.44433280579396, "Arthritis": 3.9038755677663466, "Balance disorder": 2.4363098382793997, "Basal ganglia stroke": 1279.3293503412715, "Behaviour disorder": 115.3863953710028, "Carotid artery stenosis": 58.28750891002685, "Cerebral infarction": 5.447597248538198, "Cholestasis": 4.561354074717738, "Cognitive disorder": 5.429828504700485, "Condition aggravated": 2.429682633592164, "Confusional state": 2.5346209226252983, "Cystic fibrosis": 92.85989836104471, "Depression": 2.024009624465931, "Disinhibition": 46.48321769964711, "Drug abuse": 17.285453545261063, "Drug dependence": 6.837390555835788, "Drug ineffective for unapproved indication": 4.169940626284627, "Drug interaction": 10.235501168424896, "Drug level increased": 22.37793394794624, "Drug resistance": 2.517949753545401, "Dysarthria": 4.220369824274967, "Dyskinesia": 2.270507392317191, "Epilepsy": 7.822489278520348, "Facial paralysis": 6.029554301778748, "Fibromyalgia": 8.89091662842922, "Hepatic enzyme increased": 2.034996503835309, "Hepatitis": 2.665927530092933, "Hypersexuality": 88.82331307979784, "Intervertebral disc protrusion": 18.95311135418196, "Lethargy": 4.37397642326073, "Leukocytosis": 5.210673312692011, "Liver function test abnormal": 4.77127703389505, "Malignant cranial nerve neoplasm": 6173.011979038408, "Metal poisoning": 132.0096209278199, "Metastases to liver": 4.847550654733778, "Metastases to spine": 37.158299060983616, "Multiple-drug resistance": 261.95180239719457, "Nerve compression": 22.40117854522213, "Neuroblastoma recurrent": 545.5897569526122, "Off label use": 3.039040135688306, "Osteoarthritis": 6.11201945184307, "Ovarian cyst": 18.36312986808593, "Pallor": 3.392184079839612, "Panic attack": 3.5010844484843004, "Petit mal epilepsy": 11.787846729550232, "Poisoning": 9.56235383226558, "Psychotic disorder": 8.818956485500166, "Restlessness": 3.7253722683522814, "Retro-orbital neoplasm": 2835.8261528496346, "Scar pain": 228.33166332942892, "Sedation": 9.526209467297024, "Seizure": 6.881115749556594, "Serotonin syndrome": 6.00236011520579, "Skin reaction": 8.68376266470596, "Somnolence": 3.613030351597581, "Status epilepticus": 11.094669733373134, "Stress": 2.7654569226944017, "Substance abuse": 7.623263944840117, "Substance use disorder": 89.64153421599345, "Withdrawal syndrome": 3.01035476977939}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/234.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/234.json
index d8924cd3193..66fc9f8df8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/234.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/234.json
@@ -1 +1 @@
-{"Abdominal distension ": 4.538216519995293, "Abnormal behaviour ": 3.615431389128957, "Agitation ": 5.122439129672968, "Akinesia ": 37.022900387103135, "Balance disorder ": 2.569513219974195, "Benign prostatic hyperplasia ": 14.13276579793092, "Blood chloride increased ": 66.95389642497081, "Blood creatine phosphokinase increased ": 2.0663930192786464, "Blood pressure decreased ": 2.139381728400978, "Bradykinesia ": 41.10408680633508, "Cerebral hypoperfusion ": 323.7115246479943, "Condition aggravated ": 2.538841966981786, "Confusional state ": 2.06567090394323, "Constipation ": 5.150106386113514, "Delirium ": 2.239107164397063, "Delusion ": 15.291347673380768, "Depressed mood ": 7.659685820049332, "Dopamine dysregulation syndrome ": 182.7407884871538, "Drug interaction ": 3.7482249508320775, "Drug level increased ": 4.113538364510226, "Drug withdrawal syndrome ": 2.3575503934112083, "Dry mouth ": 4.424265119600345, "Dyskinesia ": 23.339915167735445, "Dystonia ": 14.559868830160468, "Eye pruritus ": 19.940761568079747, "Fall ": 4.565679862697627, "Freezing phenomenon ": 195.7571714141756, "Gait disturbance ": 5.465816621303948, "Gambling disorder ": 56.06616473204656, "Hallucination ": 10.349545374123627, "Hallucination, auditory ": 12.768091093250442, "Hallucination, visual ": 19.09481674621866, "Head injury ": 5.496764796895023, "Hypersexuality ": 95.34058254228134, "Hypersomnia ": 4.347881225584343, "Hypotension ": 3.852557807913147, "Impulse-control disorder ": 86.50550160601635, "Incorrect dose administered ": 4.089893222747718, "Lacrimation increased ": 17.266409916684143, "Loss of personal independence in daily activities ": 5.758863028851672, "Motor dysfunction ": 11.06582596302105, "Movement disorder ": 3.965406088917108, "Muscle rigidity ": 19.930454164925457, "Musculoskeletal stiffness ": 2.4880036206940472, "Neuroleptic malignant syndrome ": 14.682078768238997, "Neutrophil count increased ": 11.9505496012003, "Nightmare ": 5.149905987150091, "Oedema peripheral ": 2.133083330380152, "On and off phenomenon ": 533.3204676001469, "Orthostatic hypotension ": 4.559789739459665, "Parkinson's disease ": 102.86727421896629, "Parkinson's disease psychosis ": 2848.169582419294, "Parkinsonian rest tremor ": 288.99640557645824, "Parkinsonism ": 13.175958269772584, "Parkinsonism hyperpyrexia syndrome ": 967.5378719692492, "Psychotic disorder ": 9.285230648564603, "Restless legs syndrome ": 6.680430600806018, "Screaming ": 12.760907059001465, "Serotonin syndrome ": 4.394180012137349, "Somnolence ": 2.0868201376493394, "Speech disorder ": 5.413786438399397, "Status epilepticus ": 4.062561850482366, "Stereotypy ": 65.55914192338523, "Stress cardiomyopathy ": 13.145547690615048, "Subarachnoid haemorrhage ": 5.683686776887623, "Sudden onset of sleep ": 110.3429559292266, "Temperature intolerance ": 11.711141254296294, "Therapeutic response shortened ": 52.16352264268834, "Tremor ": 2.1074084762489163, "Underdose ": 7.5794908981817395, "Vertigo ": 3.560182001500597, "Vitamin B12 decreased ": 228.5587609378844, "Wrong technique in product usage process ": 3.846212459437659}
\ No newline at end of file
+{"Toxicity to various agents": 16.95599428910996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/235.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/235.json
index 439e879e5a7..466d0104f0a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/235.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/235.json
@@ -1 +1 @@
-{"Adverse drug reaction ": 158.68681068071453, "Completed suicide ": 73.08718125273737, "Death ": 30.24376155033592, "Toxicity to various agents ": 55.85553523051466}
\ No newline at end of file
+{"Acute coronary syndrome": 3.011579552348646, "Adenocarcinoma": 12.051493242314654, "Anaemia": 2.2302233821275803, "Arteriospasm coronary": 12.150336396887974, "Ascites": 3.827954703293005, "Bacteraemia": 2.2246264500241613, "Blood albumin decreased": 3.4118776368735686, "Blood iron decreased": 2.846506353598159, "Blood magnesium decreased": 8.295574104411465, "Blood pressure diastolic decreased": 3.798594336727516, "Blood pressure systolic decreased": 3.3390626975482824, "Bone lesion": 16.42237096642249, "Breast cancer": 6.388895182797506, "Breast cancer metastatic": 33.45557226436214, "Breast cancer recurrent": 27.31789418372708, "Breast disorder": 15.680827329561756, "Cachexia": 3.570524808244387, "Carcinoembryonic antigen increased": 14.027594103980922, "Cardiogenic shock": 2.4619334589528603, "Cardiotoxicity": 27.77345307059434, "Colitis": 2.004363142838117, "Colon cancer metastatic": 18.075484032921047, "Colorectal cancer metastatic": 15.91871595095995, "Cytopenia": 5.291717628158027, "Diarrhoea": 3.433316447338849, "Dihydropyrimidine dehydrogenase deficiency": 181.5804645448182, "Disease progression": 8.629844968348149, "Disease recurrence": 2.976671515626132, "Drug intolerance": 2.9345839334111026, "Drug-induced liver injury": 3.4620555421577293, "Ejection fraction decreased": 4.295712838438716, "Electrolyte imbalance": 5.045204901556288, "Enteritis": 11.7759730299285, "Enterocolitis": 5.457023765817839, "Faeces soft": 3.623931464055417, "Febrile neutropenia": 2.503621248196435, "Foetal growth restriction": 2.498361696939574, "Gastrointestinal toxicity": 25.06898519970581, "Gingival pain": 2.7097286272148766, "Granulocyte count decreased": 7.464779378129253, "Granulocytopenia": 5.658196551538851, "Groin pain": 2.187006322456696, "Haematotoxicity": 14.95689403558011, "Hand dermatitis": 19.580147590345376, "Hepatic lesion": 10.744089688597846, "Hepatotoxicity": 4.857226050939679, "Hiccups": 3.786307735107498, "Hyperammonaemic encephalopathy": 6.295420244631099, "Hyperbilirubinaemia": 2.60241979086696, "Hypercholesterolaemia": 4.288158325527211, "Hypertransaminasaemia": 3.9010831884884505, "Hypoalbuminaemia": 3.0690309087075587, "Hypokalaemia": 2.2165649061482218, "Ileus": 2.1853575552277937, "Immunosuppression": 6.85745763395408, "Invasive ductal breast carcinoma": 12.229958276106494, "Lacrimation increased": 2.5855902840513982, "Laryngospasm": 6.454868187428778, "Left ventricular dysfunction": 5.862944420941027, "Leukopenia": 4.457480493528664, "Liver injury": 2.112903462920692, "Lymphangiosis carcinomatosa": 15.316460427428714, "Malignant neoplasm progression": 12.440791278281704, "Metastases to bone": 37.33983746186392, "Metastases to central nervous system": 23.184664464638796, "Metastases to eye": 85.99277676160573, "Metastases to liver": 35.044179480167394, "Metastases to lung": 20.82293444412094, "Metastases to lymph nodes": 27.85728891161123, "Metastases to meninges": 16.350004507027172, "Metastases to peritoneum": 14.302328152877145, "Metastases to skin": 71.84643351762631, "Metastases to spine": 17.70889865359296, "Metastases to the mediastinum": 47.183346331412864, "Metastasis": 8.695233229551581, "Metastatic neoplasm": 9.274658337598597, "Mucosal inflammation": 12.138040529391828, "Myelodysplastic syndrome": 4.499480231143266, "Myelosuppression": 28.28382684720369, "Myositis": 2.6475425150614376, "Nail disorder": 5.097131123146316, "Neoplasm progression": 4.2088649848834345, "Neuropathy peripheral": 9.16328771350673, "Neurotoxicity": 12.0698877284344, "Neutropenia": 8.296697611174999, "Neutrophil count decreased": 7.889918935901502, "Oesophagitis": 2.9325609371872137, "Osteolysis": 16.10761687216456, "Osteonecrosis of jaw": 4.156931506701365, "PIK3CA-activated mutation": 125.05764910487795, "Palmar-plantar erythrodysaesthesia syndrome": 18.68923197649776, "Pancreatic neuroendocrine tumour": 29.45549400242277, "Pancreatic neuroendocrine tumour metastatic": 45.93676545170948, "Pancytopenia": 2.6531733068672474, "Peripheral sensory neuropathy": 7.453725649784548, "Platelet count decreased": 6.90965029752372, "Pneumonitis": 3.534368708248067, "Polyneuropathy": 5.2549336965533, "Portal hypertension": 7.189873857819523, "Posterior reversible encephalopathy syndrome": 3.10251009297439, "Product use in unapproved indication": 2.569178121240113, "Protein total increased": 13.137836229531482, "Pulmonary mass": 4.213353277376842, "Recall phenomenon": 50.10321851502408, "Recurrent cancer": 35.540432407836505, "Seasonal allergy": 2.594722771394552, "Second primary malignancy": 2.524240467269103, "Skin fissures": 7.490617293795264, "Skin mass": 3.14861897872978, "Skin toxicity": 12.778642912975087, "Stomatitis": 2.863068338336812, "Therapy partial responder": 9.56290532868146, "Thrombocytopenia": 6.147937926720024, "Tumour marker increased": 20.707129199067424, "Venoocclusive liver disease": 8.227285053109131, "Vulvovaginal pain": 7.680951953905511, "White blood cell count decreased": 6.287019176856222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/236.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/236.json
index d2166ff5133..54ec40ef3c6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/236.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/236.json
@@ -1 +1 @@
-{"Acute kidney injury ": 3.586154188603485, "Acute respiratory distress syndrome ": 4.095297045844945, "Anaemia ": 3.91475934249942, "Ascites ": 2.231609080132509, "Atypical haemolytic uraemic syndrome ": 125.2988117791388, "Blood calcium increased ": 13.519652356514186, "Blood disorder ": 13.588368742216788, "Bone marrow disorder ": 30.57406977703992, "Brain fog ": 2.364148667991097, "COVID-19 pneumonia ": 6.442341148300263, "Cardiac failure ": 7.921397964258017, "Cardiac failure acute ": 7.421852936463756, "Cardiogenic shock ": 3.787799719375313, "Cardiotoxicity ": 10.56078635281966, "Cellulitis ": 2.381042815510983, "Cerebral toxoplasmosis ": 346.38354887758703, "Cytokine release syndrome ": 6.114551900210716, "Cytopenia ": 23.260600354078083, "Deep vein thrombosis ": 2.2046150290681408, "Disease progression ": 4.80838762575627, "Ejection fraction decreased ": 4.879307666173311, "Febrile neutropenia ": 6.068337836788587, "Fibrosis ": 19.57872538891105, "Gastrointestinal disorder ": 2.1598380373926997, "Haematotoxicity ": 6.904265484684573, "Haemolytic anaemia ": 5.753997062088401, "Haemolytic uraemic syndrome ": 21.999287860977063, "Hepatic steatosis ": 3.226085907701021, "Hypogammaglobulinaemia ": 19.84885522181084, "Infection ": 2.570526223708381, "Infusion related reaction ": 4.64161664692704, "Intentional product use issue ": 15.965461379054137, "JC virus infection ": 176.87886588837085, "Leukopenia ": 2.438133215444721, "Light chain disease ": 478.0959556872116, "Lymphopenia ": 6.26311114086344, "Microangiopathic haemolytic anaemia ": 123.67520185412064, "Mucosal inflammation ": 3.4873631141885566, "Multiple organ dysfunction syndrome ": 4.016244281530759, "Myelodysplastic syndrome ": 5.280110016837126, "Myelosuppression ": 5.193264158219974, "Neuropathy peripheral ": 6.838555830819514, "Neutropenia ": 4.186292116437014, "Neutrophil count decreased ": 2.0320714775485835, "Off label use ": 6.008425233754755, "Osteolysis ": 78.98700905819479, "Pancytopenia ": 5.327846393984082, "Plasma cell leukaemia ": 126.26456772180592, "Plasma cell myeloma ": 250.1091458598949, "Plasma cell myeloma recurrent ": 310.350688266078, "Plasma cell myeloma refractory ": 656.2514909092383, "Plasmacytoma ": 185.76647810811983, "Platelet count decreased ": 3.1280912169908084, "Pleural effusion ": 3.834160665216909, "Pneumonia ": 3.281261112676458, "Pneumonia fungal ": 15.855721888869745, "Polyneuropathy ": 4.587445772602574, "Posterior reversible encephalopathy syndrome ": 5.376729770695204, "Progressive multifocal leukoencephalopathy ": 77.86589480704242, "Pulmonary arterial hypertension ": 5.5852202288959525, "Pulmonary hypertension ": 7.912097822110903, "Pulmonary oedema ": 3.3749397771239984, "Pulseless electrical activity ": 12.880417950559016, "Renal failure ": 2.457708653547597, "Respiratory failure ": 2.9526377920352505, "Respiratory tract infection ": 4.527596176327422, "Sepsis ": 4.3327896255918334, "Septic shock ": 2.0127512214655607, "Therapeutic product effect incomplete ": 3.1325303580485366, "Therapy non-responder ": 15.594602255416696, "Therapy partial responder ": 65.97417361169826, "Thrombocytopenia ": 6.240890183672321, "Thrombotic microangiopathy ": 86.20752151095459, "Tumour lysis syndrome ": 36.2736609350323, "Upper respiratory tract infection ": 2.0288176340708763}
\ No newline at end of file
+{"Acne": 27.746559207382862, "Blood calcitonin increased": 2023.5237525885243, "Blood calcium decreased": 16.183524073014254, "Blood pressure increased": 2.5734886401115658, "Blood thyroid stimulating hormone increased": 18.479056598280355, "Carcinoembryonic antigen increased": 73.06501686625204, "Dehydration": 2.156288556649665, "Diarrhoea": 4.948524431353576, "Disease progression": 6.099002914542631, "Dry skin": 9.078980022181668, "Electrocardiogram QT prolonged": 42.41802507870104, "Hospitalisation": 7.2893515022466335, "Hypertension": 3.246480083110252, "Hypocalcaemia": 13.812540258386909, "Malignant neoplasm progression": 2.1683079265871723, "Neoplasm progression": 3.644448726396821, "Photosensitivity reaction": 20.36682090496372, "Rash": 2.6332870016480885, "Skin exfoliation": 5.543495736990219}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/237.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/237.json
index 943ac3d1366..3a2b74defb6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/237.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/237.json
@@ -1 +1 @@
-{"Accidental exposure to product ": 26.793883643369128, "Acne ": 18.9497138153202, "Aggression ": 10.926777059125843, "Akathisia ": 79.92834982480295, "Blood prolactin increased ": 136.79080639331687, "Cardiac arrest ": 5.445184486571681, "Completed suicide ": 12.966666581606033, "Delusion ": 47.21875423481784, "Delusion of grandeur ": 687.8930317540205, "Depressed mood ": 10.236132009041684, "Drug interaction ": 3.09633169117244, "Drug resistance ": 20.66326783732023, "Dystonia ": 45.30758212232775, "Eating disorder ": 28.250140462176905, "Extrapyramidal disorder ": 39.464137526062856, "Hallucination, auditory ": 31.807090427007594, "Insomnia ": 3.116797218493686, "Lymphocyte count decreased ": 45.00167105885801, "Mental impairment ": 22.61356722903168, "Neglect of personal appearance ": 3436.650574946053, "Neutrophil count decreased ": 6.802652650612, "Off label use ": 2.043128423944615, "Orthostatic hypotension ": 20.973342188298822, "Overdose ": 3.214016692650831, "Parkinsonism ": 88.298763168657, "Pneumonia aspiration ": 22.40740346294968, "Psoriasis ": 9.92761212615132, "Red blood cell sedimentation rate decreased ": 2121.8609380328053, "Sedation ": 28.993508603164717, "Slow speech ": 193.9394958766189, "Strabismus ": 137.18559849467545, "Suicidal ideation ": 12.797176828077571, "Suspected suicide ": 147.71755676053294, "Thinking abnormal ": 52.97794678812984, "Toxicity to various agents ": 5.09512858683184, "Treatment noncompliance ": 38.12952200795059, "Vitamin D decreased ": 125.5708508860112, "Weight decreased ": 2.6920873052523704, "Withdrawal syndrome ": 13.889161987240223}
\ No newline at end of file
+{"Constipation": 3.1145794788476486, "Drug ineffective": 4.61374138769095, "Immune thrombocytopenia": 220.03782577967883, "Impaired quality of life": 236.55201943217665, "Impaired work ability": 64.17147643935897, "Loss of personal independence in daily activities": 9.354370405041324, "Muscle spasms": 3.6305471763679775, "Poor quality sleep": 81.46797197332828, "Product use in unapproved indication": 5.170714561162338, "Suicidal ideation": 6.526078845143178, "Therapy non-responder": 153.35537336922025, "Weight increased": 22.949900014465992, "Withdrawal syndrome": 17.252122727912}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/238.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/238.json
index d8e08b5b95b..de5944fdd46 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/238.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/238.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 42.75859542468945, "Acute respiratory distress syndrome ": 3.9642173008982144, "Anaemia ": 2.310907027196997, "Aspergillus infection ": 17.246744755243064, "B-cell lymphoma recurrent ": 235.7076294463422, "BK virus infection ": 25.8132013532908, "Bacteraemia ": 11.825149944179778, "Bacterial infection ": 9.056731761608964, "Blood lactate dehydrogenase increased ": 8.406682324824763, "Bone lesion ": 62.60948007864048, "Bronchopulmonary aspergillosis ": 16.246830411481817, "Candida infection ": 5.469791678663731, "Clostridium difficile colitis ": 11.386443904039048, "Colitis ": 7.993067130491874, "Cystitis haemorrhagic ": 15.226128801722451, "Cytomegalovirus infection ": 5.424477503338146, "Cytomegalovirus infection reactivation ": 42.78955912100677, "Cytopenia ": 24.80399215363396, "Diffuse large B-cell lymphoma ": 31.67731317669775, "Diffuse large B-cell lymphoma recurrent ": 205.6403978976627, "Diffuse large B-cell lymphoma refractory ": 69.82304652318464, "Disease progression ": 23.759761268715145, "Disease recurrence ": 8.6425599556636, "Enteritis ": 33.228963411339805, "Epstein-Barr virus infection reactivation ": 30.197945431269453, "Febrile neutropenia ": 36.17453827670129, "Fungal infection ": 7.79750429337409, "Gastric cancer ": 7.934386489609373, "Gastrointestinal toxicity ": 20.46131854364733, "Graft versus host disease ": 19.98814560118569, "Granulocytopenia ": 6.7464046521267225, "Haematotoxicity ": 91.91135750287236, "Hepatic cyst ": 29.015323312332637, "Hepatitis B reactivation ": 15.516634258955971, "Hepatitis acute ": 6.311460372249967, "Hepatotoxicity ": 4.956630564305426, "Hodgkin's disease ": 33.858763843380395, "Hodgkin's disease recurrent ": 575.0677120621181, "Ill-defined disorder ": 4.719764665112564, "Infection ": 3.252099430036429, "Intentional product use issue ": 3.608205769563999, "JC virus infection ": 126.61304747228668, "Kaposi's sarcoma ": 40.38646349054193, "Klebsiella bacteraemia ": 173.3695267637119, "Lymphoma ": 18.73150043133445, "Lymphopenia ": 7.681563915256989, "Malignant neoplasm progression ": 2.3766976935474866, "Mantle cell lymphoma recurrent ": 533.6099424136872, "Metastatic lymphoma ": 162.38853222426616, "Mucosal inflammation ": 34.98697437223768, "Myelodysplastic syndrome ": 81.4027984094622, "Myelodysplastic syndrome with excess blasts ": 187.05989123202315, "Myelosuppression ": 3.967085255369893, "Nephropathy toxic ": 4.777767750232702, "Neuropathy peripheral ": 2.3385235808468554, "Neutropenia ": 4.235864003759994, "Neutropenic sepsis ": 42.005298328183, "Neutrophil count decreased ": 2.2197928452518907, "Non-Hodgkin's lymphoma ": 56.93476936728541, "Non-Hodgkin's lymphoma recurrent ": 567.372300187744, "Off label use ": 4.776971565579615, "Pancytopenia ": 10.547358989551524, "Plasma cell myeloma ": 2.309216098104557, "Pneumocystis jirovecii pneumonia ": 20.318614157098374, "Pneumonia ": 2.675826417987213, "Pneumonitis ": 8.776898531720585, "Polychromasia ": 281.1710476480148, "Post transplant lymphoproliferative disorder ": 32.85664997954095, "Product use in unapproved indication ": 2.631107694645254, "Progressive multifocal leukoencephalopathy ": 35.32857658513915, "Pulmonary toxicity ": 8.267271925146948, "Respiratory failure ": 2.6021818142274387, "Second primary malignancy ": 38.05057265653156, "Sepsis ": 4.959299852254206, "Septic shock ": 5.833560595534096, "Staphylococcal infection ": 3.13841633132439, "Stomatitis ": 4.7923938226571625, "Systemic mycosis ": 76.24867406233687, "Therapy non-responder ": 2.868619613134332, "Therapy partial responder ": 13.8483616178848, "Thrombocytopenia ": 7.873129867272499, "Venoocclusive liver disease ": 58.05605697475786}
\ No newline at end of file
+{"Abdominal distension": 4.530899969771802, "Abnormal behaviour": 3.6096053274572095, "Agitation": 5.114180028648252, "Akinesia": 36.96324373022631, "Balance disorder": 2.5653717942735645, "Benign prostatic hyperplasia": 14.109993673882244, "Blood chloride increased": 66.84599916920449, "Blood creatine phosphokinase increased": 2.0630631440539915, "Blood pressure decreased": 2.135864312684378, "Bradykinesia": 41.0378374359531, "Cerebral hypoperfusion": 323.18982521523907, "Condition aggravated": 2.5347477779842325, "Confusional state": 2.0623403955861552, "Constipation": 5.141799513108487, "Delirium": 2.2354989701921126, "Delusion": 15.266700769475868, "Depressed mood": 7.64733621518071, "Dopamine dysregulation syndrome": 182.44633487782136, "Drug interaction": 3.742179026003503, "Drug level increased": 4.10690981762254, "Drug withdrawal syndrome": 2.353751551745864, "Dry mouth": 4.417132282635879, "Dyskinesia": 23.30226691773088, "Dystonia": 14.53640192749762, "Eye pruritus": 19.908613523330867, "Fall": 4.558197264878199, "Freezing phenomenon": 195.44164740913732, "Gait disturbance": 5.456900978243721, "Gambling disorder": 55.97581084541248, "Hallucination": 10.332850694989515, "Hallucination, auditory": 12.747511218165664, "Hallucination, visual": 19.06402630768352, "Head injury": 5.487906837216118, "Hypersexuality": 95.18692555569451, "Hypersomnia": 4.340875059307174, "Hypotension": 3.8462539708780032, "Impulse-control disorder": 86.366077507589, "Incorrect dose administered": 4.083300904835598, "Lacrimation increased": 17.238572466925273, "Loss of personal independence in daily activities": 5.749578091185247, "Motor dysfunction": 11.047993551196289, "Movement disorder": 3.959015891206772, "Muscle rigidity": 19.89832495979181, "Musculoskeletal stiffness": 2.4839932364555986, "Neuroleptic malignant syndrome": 14.658409852232866, "Neutrophil count increased": 11.931293677120903, "Nightmare": 5.141605603502435, "Oedema peripheral": 2.129592396740722, "On and off phenomenon": 532.4606717985048, "Orthostatic hypotension": 4.551461487331177, "Parkinson's disease": 102.70129643963033, "Parkinson's disease psychosis": 2843.5807093904887, "Parkinsonian rest tremor": 288.5307595850282, "Parkinsonism": 13.154723313172632, "Parkinsonism hyperpyrexia syndrome": 965.97898000275, "Psychotic disorder": 9.270262220614828, "Restless legs syndrome": 6.669665471513686, "Screaming": 12.740345407600287, "Serotonin syndrome": 4.387098851481629, "Somnolence": 2.0834321036786845, "Speech disorder": 5.405059682680407, "Status epilepticus": 4.056015837522272, "Stereotypy": 65.4535070949904, "Stress cardiomyopathy": 13.124366268631064, "Subarachnoid haemorrhage": 5.674528644206311, "Sudden onset of sleep": 110.165108922598, "Temperature intolerance": 11.692271088444596, "Therapeutic response shortened": 52.07944485007366, "Tremor": 2.1039309676194504, "Underdose": 7.567274891668005, "Vertigo": 3.554441695984958, "Vitamin B12 decreased": 228.19029553873088, "Wrong technique in product usage process": 3.840013046378513}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/239.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/239.json
index 59f8bf25714..ed5f66eeac2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/239.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/239.json
@@ -1 +1 @@
-{"Abdominal infection ": 73.40130016887204, "Acinetobacter infection ": 47.24532103793901, "Acute generalised exanthematous pustulosis ": 17.754355552551747, "Acute myeloid leukaemia ": 3.762917777509261, "Acute respiratory distress syndrome ": 8.445803643022145, "Acute respiratory failure ": 3.2844794747513832, "Arthritis bacterial ": 15.579829609146616, "Arthritis fungal ": 633.1345390859295, "Aspergillus infection ": 123.17096430585688, "Atrial fibrillation ": 2.478584467151659, "Bacteraemia ": 9.115324444665276, "Blood alkaline phosphatase increased ": 6.283481770821517, "Blood bilirubin increased ": 5.071409616957467, "Blood culture positive ": 62.59636559945123, "Bronchopulmonary aspergillosis ": 56.8478223562099, "Candida infection ": 41.04627990913524, "Candida sepsis ": 51.16930604706874, "Cellulitis ": 2.901197558477645, "Central nervous system fungal infection ": 574.5119028097828, "Cerebral aspergillosis ": 235.96961035641752, "Cholestasis ": 3.527023443307823, "Chorioretinitis ": 63.39071887548951, "Circulatory collapse ": 2.049489649751181, "Condition aggravated ": 2.372097256304457, "Cutaneous calcification ": 623.8498639281297, "Cytomegalovirus infection ": 8.666116507746466, "Deafness neurosensory ": 13.223666380999967, "Disseminated intravascular coagulation ": 6.919115430306952, "Drug ineffective ": 7.000879403279328, "Drug ineffective for unapproved indication ": 15.407117213745275, "Drug level decreased ": 12.284408923300033, "Drug reaction with eosinophilia and systemic symptoms ": 3.906726929173579, "Drug resistance ": 29.75388852693252, "Drug-induced liver injury ": 4.901527538208074, "Enterococcal infection ": 41.98246259459722, "Enterocolitis ": 11.729271279627609, "Eosinophilia ": 3.2641881468700875, "Febrile neutropenia ": 5.0771209293157264, "Fungaemia ": 207.0090693552395, "Fungal endocarditis ": 385.0219473762471, "Fungal infection ": 22.41872311631253, "Fusarium infection ": 178.7844656559994, "Gamma-glutamyltransferase increased ": 2.0420539005657545, "Graft versus host disease ": 7.052988596759614, "Haematocrit decreased ": 10.08771034552078, "Haemophagocytic lymphohistiocytosis ": 7.296665380041955, "Haemoptysis ": 3.125288015284393, "Hepatic cytolysis ": 2.7210209117409585, "Hepatic failure ": 3.873910618107945, "Hepatic function abnormal ": 2.3528226303033843, "Hepatotoxicity ": 9.668283011896508, "Hydrocephalus ": 10.15174630840824, "Hyperbilirubinaemia ": 6.6184060113658045, "Hypercapnia ": 19.25129509686071, "Hypervolaemia ": 8.447805013972856, "Hypoalbuminaemia ": 15.573376294223124, "Hypokalaemia ": 3.2962384201566173, "Hypomagnesaemia ": 6.368665930082398, "Hypoxia ": 3.275082463322547, "Infection ": 2.241306870191206, "Jaundice cholestatic ": 7.665421988098072, "Leukaemia recurrent ": 36.85167843717864, "Liver function test abnormal ": 2.9071983011082634, "Liver function test increased ": 3.473224613704249, "Lower respiratory tract infection fungal ": 314.3160854528656, "Mucormycosis ": 130.04818223746466, "Multiple organ dysfunction syndrome ": 24.598947909825156, "Multiple-drug resistance ": 6.244033658629087, "Nephropathy toxic ": 10.695950586667625, "Neurological decompensation ": 22.90979267784319, "Neutropenia ": 2.536129748331577, "Oral candidiasis ": 5.516021599530959, "Ototoxicity ": 35.92219244618255, "Pallor ": 3.7841059764973184, "Pancytopenia ": 2.709874113172724, "Parenteral nutrition associated liver disease ": 407.845926029848, "Pathogen resistance ": 42.36796436158664, "Pharyngitis ": 6.454624956109873, "Pneumocystis jirovecii infection ": 53.62121961048446, "Pneumonia ": 2.266062260788043, "Pneumonia bacterial ": 8.66790693928, "Product use in unapproved indication ": 3.5786553241074825, "Pseudomonas infection ": 32.45388870286651, "Pulmonary mass ": 6.206885209668884, "Rash maculo-papular ": 9.530723214285532, "Renal failure ": 2.358619087469169, "Renal impairment ": 2.1031337202709337, "Respiratory distress ": 2.833815884556932, "Respiratory failure ": 6.748771565181686, "Scedosporium infection ": 146.56999985542103, "Sepsis ": 7.145030027663128, "Septic shock ": 22.75027581385154, "Skin exfoliation ": 3.5865656506980783, "Skin lesion ": 5.240745149143815, "Skin necrosis ": 6.663962703438559, "Stenotrophomonas infection ": 150.69390469640794, "Streptococcal infection ": 29.846691693096474, "Systemic candida ": 100.571596874052, "Systemic mycosis ": 97.9650393519305, "Tachypnoea ": 2.365878417501478, "Therapy non-responder ": 9.570444032361396, "Toxic epidermal necrolysis ": 13.241548939717738, "Toxic skin eruption ": 4.486098956338444, "Transaminases increased ": 4.1333777356422585, "Treatment failure ": 6.390981139810413, "Trichosporon infection ": 237.0318399428488, "Unresponsive to stimuli ": 3.5960029992679075}
\ No newline at end of file
+{"Adverse drug reaction": 158.68681068071453, "Completed suicide": 73.08718125273737, "Death": 30.24376155033592, "Toxicity to various agents": 55.85553523051466}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/24.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/24.json
index 8220f56d310..3d5a6883dd7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/24.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/24.json
@@ -1 +1 @@
-{"Abortion induced ": 7.237452877445067, "Abscess ": 8.31855174511245, "Accidental overdose ": 4.187485096400902, "Anuria ": 4.604732110523533, "Arteriosclerosis coronary artery ": 16.767488677491823, "Asphyxia ": 12.634981242525924, "Blood glucose abnormal ": 7.130757524787525, "Blood glucose decreased ": 8.137205291976633, "Blood glucose fluctuation ": 35.44021146286171, "Blood glucose increased ": 18.67705150122187, "COVID-19 pneumonia ": 10.448021533724388, "Cardiac disorder ": 2.652406787140249, "Coma ": 2.5153928242969834, "Condition aggravated ": 7.612795996865404, "Dehiscence ": 771.4370357557297, "Dermatitis allergic ": 2.4796739850653986, "Device failure ": 44.81649003706615, "Device issue ": 9.381893517130438, "Device malfunction ": 13.21741262764763, "Diabetes mellitus inadequate control ": 11.34641026278777, "Diabetic coma ": 58.117475163788185, "Diabetic foot ": 22.56599025086869, "Diabetic hyperglycaemic coma ": 121.4428010700712, "Diabetic ketoacidosis ": 6.956915140463213, "Drug hypersensitivity ": 4.199132643288808, "Exposure during pregnancy ": 3.7082263932184256, "Extra dose administered ": 8.751528734546733, "Foetal exposure during pregnancy ": 2.909382303100484, "Glycosylated haemoglobin increased ": 10.672403628470969, "Haematocrit decreased ": 2.8540721932572395, "Hepatic steatosis ": 4.572345449220898, "Hyperglycaemia ": 21.794126062401197, "Hyperinsulinaemic hypoglycaemia ": 48.3005349599956, "Hypoglycaemia ": 48.13936637651637, "Hypoglycaemic coma ": 64.03942587244862, "Hypoglycaemic seizure ": 29.959368756581004, "Hypoglycaemic unconsciousness ": 29.317153712174655, "Hypothermia ": 4.73765141438557, "Incorrect dose administered ": 3.402394032769598, "Incorrect dose administered by device ": 27.30343797426918, "Injection site abscess ": 19.445792850003738, "Injection site ulcer ": 72.07452070892896, "Insulin resistance ": 21.031783213450478, "Ketoacidosis ": 10.444151458625472, "Lactic acidosis ": 2.5535677290363106, "Lipodystrophy acquired ": 18.486994368373526, "Loss of consciousness ": 2.96696138570018, "Medication error ": 4.693481095594937, "Nikolsky's sign ": 104.10362586681872, "Pneumocystis jirovecii pneumonia ": 11.995337305180469, "Premature baby ": 4.277366932055089, "Premature delivery ": 7.798892225614347, "Product administration error ": 3.961530675818505, "Product leakage ": 7.336652671392606, "Product physical issue ": 7.995969630384268, "Product quality issue ": 10.088048977106665, "Product storage error ": 8.633175288682734, "Pulmonary infarction ": 53.37005354475439, "Respiratory alkalosis ": 90.13850669911108, "Respiratory failure ": 24.605239513214, "SARS-CoV-2 test positive ": 6.7637408373775605, "Shock hypoglycaemic ": 342.5580365368121, "Skin erosion ": 13.122778890193228, "Sopor ": 7.838605003762248, "Stevens-Johnson syndrome ": 4.597069127557772, "Superficial vein thrombosis ": 9.912164278037086, "Supraventricular tachycardia ": 11.643428819285306, "Toxic epidermal necrolysis ": 14.423900937408742, "Toxic skin eruption ": 2.936809930335765, "Treatment noncompliance ": 3.8613732750715655, "Type IV hypersensitivity reaction ": 35.18247295899008, "Wrong product administered ": 16.329528189158147, "Wrong technique in product usage process ": 3.2197153790718134}
\ No newline at end of file
+{"Blood glucose decreased": 13.51894874585776, "Blood glucose increased": 26.998733641471016, "Cold sweat": 16.90067023250686, "Hyperhidrosis": 3.458195749106008, "Hypoglycaemia": 55.75845621501416, "Hypoglycaemic coma": 170.29349442168697, "Liquid product physical issue": 146.44913670522578, "Loss of consciousness": 6.761450014371626, "Shock hypoglycaemic": 779.2051217499967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/240.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/240.json
index a829b4862a6..ebf7484b863 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/240.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/240.json
@@ -1 +1 @@
-{"Asthma ": 37.69826354541946, "Cystic fibrosis ": 976.0342656398344, "Drug ineffective ": 2.165753130552211, "Dyspnoea ": 6.372927458059149, "Infective pulmonary exacerbation of cystic fibrosis ": 212.1742150583465, "Loss of personal independence in daily activities ": 76.23873646718333, "Sleep disorder ": 17.36845551502997, "Sleep disorder due to a general medical condition ": 244.8819808223313, "Wheezing ": 66.6516543865157}
\ No newline at end of file
+{"Acute kidney injury": 3.5851486976304927, "Acute respiratory distress syndrome": 4.094149838556442, "Anaemia": 3.913661570091872, "Ascites": 2.2309839200119974, "Atypical haemolytic uraemic syndrome": 125.2637112436148, "Blood calcium increased": 13.515864915300591, "Blood disorder": 13.584562119208272, "Bone marrow disorder": 30.565504671558973, "Brain fog": 2.363486417080244, "COVID-19 pneumonia": 6.440536399999098, "Cardiac failure": 7.918452717187726, "Cardiac failure acute": 7.419773910700125, "Cardiogenic shock": 3.7867386506532057, "Cardiotoxicity": 10.557828043198452, "Cellulitis": 2.3803757695422783, "Cerebral toxoplasmosis": 346.2864830931254, "Cytokine release syndrome": 6.1128388062867485, "Cytopenia": 23.23546901622097, "Deep vein thrombosis": 2.203997307424602, "Disease progression": 4.807039795800443, "Ejection fraction decreased": 4.877940809146613, "Febrile neutropenia": 6.066636984106319, "Fibrosis": 19.57324064135173, "Gastrointestinal disorder": 2.1591648407306248, "Haematotoxicity": 6.9023314875150845, "Haemolytic anaemia": 5.752385116305821, "Haemolytic uraemic syndrome": 21.99312525787101, "Hepatic steatosis": 3.2251822089842617, "Hypogammaglobulinaemia": 19.8432950123894, "Infection": 2.56980588763494, "Infusion related reaction": 4.640315916973252, "Intentional product use issue": 15.960984668492689, "JC virus infection": 176.82930722414977, "Leukopenia": 2.4371426426508718, "Light chain disease": 477.96203698013977, "Lymphopenia": 6.261356570111651, "Microangiopathic haemolytic anaemia": 123.6405543500362, "Mucosal inflammation": 3.486386134200535, "Multiple organ dysfunction syndrome": 4.015118981506092, "Myelodysplastic syndrome": 5.278630910491181, "Myelosuppression": 5.191808359462111, "Neuropathy peripheral": 6.836430803330305, "Neutropenia": 4.184938197693499, "Neutrophil count decreased": 2.031502141344024, "Off label use": 6.006501615110173, "Osteolysis": 78.96488043202325, "Pancytopenia": 5.326353159020804, "Plasma cell leukaemia": 126.22919797924509, "Plasma cell myeloma": 250.0388566141349, "Plasma cell myeloma recurrent": 310.2636980620203, "Plasma cell myeloma refractory": 656.0675874662888, "Plasmacytoma": 185.71442302218583, "Platelet count decreased": 3.127214481702075, "Pleural effusion": 3.8327330681176544, "Pneumonia": 3.280341045148388, "Pneumonia fungal": 15.851280353513491, "Polyneuropathy": 4.586160675794254, "Posterior reversible encephalopathy syndrome": 5.375223660887612, "Progressive multifocal leukoencephalopathy": 77.84407383075437, "Pulmonary arterial hypertension": 5.583655652710875, "Pulmonary hypertension": 7.909881017508173, "Pulmonary oedema": 3.373550944249354, "Pulseless electrical activity": 12.876809938230435, "Renal failure": 2.4570197317343787, "Respiratory failure": 2.9515665991546904, "Respiratory tract infection": 4.526327821667148, "Sepsis": 4.331575274866037, "Septic shock": 2.012187393393294, "Therapeutic product effect incomplete": 3.1316525731392773, "Therapy non-responder": 15.588863225785818, "Therapy partial responder": 65.95567922975067, "Thrombocytopenia": 6.238551865863011, "Thrombotic microangiopathy": 86.18335270529403, "Tumour lysis syndrome": 36.26349571983143, "Upper respiratory tract infection": 2.028249328905961}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/241.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/241.json
index a612a1edc09..9381bd0a6bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/241.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/241.json
@@ -1 +1 @@
-{"Drug ineffective ": 16.541696457877734}
\ No newline at end of file
+{"Accidental exposure to product": 26.793883643369128, "Acne": 18.9497138153202, "Aggression": 10.926777059125843, "Akathisia": 79.92834982480295, "Blood prolactin increased": 136.79080639331687, "Cardiac arrest": 5.445184486571681, "Completed suicide": 12.966666581606033, "Delusion": 47.21875423481784, "Delusion of grandeur": 687.8930317540205, "Depressed mood": 10.236132009041684, "Drug interaction": 3.09633169117244, "Drug resistance": 20.66326783732023, "Dystonia": 45.30758212232775, "Eating disorder": 28.250140462176905, "Extrapyramidal disorder": 39.464137526062856, "Hallucination, auditory": 31.807090427007594, "Insomnia": 3.116797218493686, "Lymphocyte count decreased": 45.00167105885801, "Mental impairment": 22.61356722903168, "Neglect of personal appearance": 3436.650574946053, "Neutrophil count decreased": 6.802652650612, "Off label use": 2.0430479560407417, "Orthostatic hypotension": 20.968827555269566, "Overdose": 3.214016692650831, "Parkinsonism": 88.298763168657, "Pneumonia aspiration": 22.40740346294968, "Psoriasis": 9.92761212615132, "Red blood cell sedimentation rate decreased": 2121.8609380328053, "Sedation": 28.993508603164717, "Slow speech": 193.9394958766189, "Strabismus": 137.18559849467545, "Suicidal ideation": 12.797176828077571, "Suspected suicide": 147.71755676053294, "Thinking abnormal": 52.97794678812984, "Toxicity to various agents": 5.09512858683184, "Treatment noncompliance": 38.12952200795059, "Vitamin D decreased": 125.5708508860112, "Weight decreased": 2.6920873052523704, "Withdrawal syndrome": 13.889161987240223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/242.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/242.json
index 667bd2cdeea..ef8c8772be4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/242.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/242.json
@@ -1 +1 @@
-{"Drug ineffective ": 3.0331679315641398, "Drug interaction ": 5.223061880739655, "Drug resistance ": 42.43951397031212, "Off label use ": 4.350362785784459}
\ No newline at end of file
+{"Acute myeloid leukaemia": 42.75859542468945, "Acute respiratory distress syndrome": 3.9642173008982144, "Anaemia": 2.310907027196997, "Aspergillus infection": 17.246744755243064, "B-cell lymphoma recurrent": 235.7076294463422, "BK virus infection": 25.8132013532908, "Bacteraemia": 11.825149944179778, "Bacterial infection": 9.056731761608964, "Blood lactate dehydrogenase increased": 8.406682324824763, "Bone lesion": 62.60948007864048, "Bronchopulmonary aspergillosis": 16.246830411481817, "Candida infection": 5.469791678663731, "Clostridium difficile colitis": 11.386443904039048, "Colitis": 7.993067130491874, "Cystitis haemorrhagic": 15.226128801722451, "Cytomegalovirus infection": 5.424477503338146, "Cytomegalovirus infection reactivation": 42.78955912100677, "Cytopenia": 24.784157386503143, "Diffuse large B-cell lymphoma": 31.67731317669775, "Diffuse large B-cell lymphoma recurrent": 205.6403978976627, "Diffuse large B-cell lymphoma refractory": 69.82304652318464, "Disease progression": 23.759761268715145, "Disease recurrence": 8.6425599556636, "Enteritis": 33.228963411339805, "Epstein-Barr virus infection reactivation": 30.197945431269453, "Febrile neutropenia": 36.17453827670129, "Fungal infection": 7.795338135475069, "Gastric cancer": 7.934386489609373, "Gastrointestinal toxicity": 20.46131854364733, "Graft versus host disease": 19.98814560118569, "Granulocytopenia": 6.744459938897255, "Haematotoxicity": 91.91135750287236, "Hepatic cyst": 29.015323312332637, "Hepatitis B reactivation": 15.516634258955971, "Hepatitis acute": 6.311460372249967, "Hepatotoxicity": 4.956630564305426, "Hodgkin's disease": 33.858763843380395, "Hodgkin's disease recurrent": 575.0677120621181, "Ill-defined disorder": 4.719764665112564, "Infection": 3.252099430036429, "Intentional product use issue": 3.608205769563999, "JC virus infection": 126.61304747228668, "Kaposi's sarcoma": 40.38646349054193, "Klebsiella bacteraemia": 173.3695267637119, "Lymphoma": 18.73150043133445, "Lymphopenia": 7.681563915256989, "Malignant neoplasm progression": 2.3766976935474866, "Mantle cell lymphoma recurrent": 533.6099424136872, "Metastatic lymphoma": 162.38853222426616, "Mucosal inflammation": 34.98697437223768, "Myelodysplastic syndrome": 81.4027984094622, "Myelodysplastic syndrome with excess blasts": 187.05989123202315, "Myelosuppression": 3.967085255369893, "Nephropathy toxic": 4.777767750232702, "Neuropathy peripheral": 2.338452565873178, "Neutropenia": 4.235681698556986, "Neutropenic sepsis": 42.005298328183, "Neutrophil count decreased": 2.2197928452518907, "Non-Hodgkin's lymphoma": 56.93476936728541, "Non-Hodgkin's lymphoma recurrent": 567.372300187744, "Off label use": 4.776783221345876, "Pancytopenia": 10.547358989551524, "Plasma cell myeloma": 2.309216098104557, "Pneumocystis jirovecii pneumonia": 20.318614157098374, "Pneumonia": 2.675826417987213, "Pneumonitis": 8.776898531720585, "Polychromasia": 281.1710476480148, "Post transplant lymphoproliferative disorder": 32.85664997954095, "Product use in unapproved indication": 2.631025605959052, "Progressive multifocal leukoencephalopathy": 35.32857658513915, "Pulmonary toxicity": 8.267271925146948, "Respiratory failure": 2.6019668964575198, "Second primary malignancy": 38.05057265653156, "Sepsis": 4.959299852254206, "Septic shock": 5.833560595534096, "Staphylococcal infection": 3.13841633132439, "Stomatitis": 4.7923938226571625, "Systemic mycosis": 76.24867406233687, "Therapy non-responder": 2.8683689590671784, "Therapy partial responder": 13.8483616178848, "Thrombocytopenia": 7.872387953443818, "Venoocclusive liver disease": 58.05605697475786}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/243.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/243.json
index 6dda6efbd73..0fb7f3796ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/243.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/243.json
@@ -1 +1 @@
-{"General physical health deterioration ": 23.64948355769369, "Hypophagia ": 129.91825049650234, "Off label use ": 2.9458778296066823, "Placental insufficiency ": 1995.0411285213304, "Staphylococcal infection ": 101.24909970862343, "Thrombocytopenia ": 11.737579113449806, "Transaminases increased ": 46.20561549648564, "Treatment failure ": 35.35237306579503}
\ No newline at end of file
+{"Abdominal infection": 73.40130016887204, "Acinetobacter infection": 47.24532103793901, "Acute generalised exanthematous pustulosis": 17.754355552551747, "Acute myeloid leukaemia": 3.762917777509261, "Acute respiratory distress syndrome": 8.445803643022145, "Acute respiratory failure": 3.2844794747513832, "Arthritis bacterial": 15.579829609146616, "Arthritis fungal": 633.1345390859295, "Aspergillus infection": 123.17096430585688, "Atrial fibrillation": 2.4785167706998603, "Bacteraemia": 9.115324444665276, "Blood alkaline phosphatase increased": 6.283481770821517, "Blood bilirubin increased": 5.071409616957467, "Blood culture positive": 62.59636559945123, "Bronchopulmonary aspergillosis": 56.8478223562099, "Candida infection": 41.04627990913524, "Candida sepsis": 51.16930604706874, "Cellulitis": 2.901197558477645, "Central nervous system fungal infection": 574.5119028097828, "Cerebral aspergillosis": 235.96961035641752, "Cholestasis": 3.527023443307823, "Chorioretinitis": 63.39071887548951, "Circulatory collapse": 2.049489649751181, "Condition aggravated": 2.372097256304457, "Cutaneous calcification": 623.8498639281297, "Cytomegalovirus infection": 8.666116507746466, "Deafness neurosensory": 13.223666380999967, "Disseminated intravascular coagulation": 6.919115430306952, "Drug ineffective": 7.0008275353431, "Drug ineffective for unapproved indication": 15.407117213745275, "Drug level decreased": 12.284408923300033, "Drug reaction with eosinophilia and systemic symptoms": 3.90640402459066, "Drug resistance": 29.75388852693252, "Drug-induced liver injury": 4.901228407189881, "Enterococcal infection": 41.98246259459722, "Enterocolitis": 11.729271279627609, "Eosinophilia": 3.2641881468700875, "Febrile neutropenia": 5.0771209293157264, "Fungaemia": 207.0090693552395, "Fungal endocarditis": 385.0219473762471, "Fungal infection": 22.41245824824658, "Fusarium infection": 178.7844656559994, "Gamma-glutamyltransferase increased": 2.0420539005657545, "Graft versus host disease": 7.052988596759614, "Haematocrit decreased": 10.08771034552078, "Haemophagocytic lymphohistiocytosis": 7.296665380041955, "Haemoptysis": 3.125288015284393, "Hepatic cytolysis": 2.7210209117409585, "Hepatic failure": 3.873910618107945, "Hepatic function abnormal": 2.3528226303033843, "Hepatotoxicity": 9.668283011896508, "Hydrocephalus": 10.15174630840824, "Hyperbilirubinaemia": 6.6184060113658045, "Hypercapnia": 19.25129509686071, "Hypervolaemia": 8.447805013972856, "Hypoalbuminaemia": 15.573376294223124, "Hypokalaemia": 3.2962384201566173, "Hypomagnesaemia": 6.368665930082398, "Hypoxia": 3.275082463322547, "Infection": 2.241306870191206, "Jaundice cholestatic": 7.665421988098072, "Leukaemia recurrent": 36.85167843717864, "Liver function test abnormal": 2.9071983011082634, "Liver function test increased": 3.473224613704249, "Lower respiratory tract infection fungal": 314.3160854528656, "Mucormycosis": 130.04818223746466, "Multiple organ dysfunction syndrome": 24.598947909825156, "Multiple-drug resistance": 6.244033658629087, "Nephropathy toxic": 10.695950586667625, "Neurological decompensation": 22.90979267784319, "Neutropenia": 2.5360206148305986, "Oral candidiasis": 5.516021599530959, "Ototoxicity": 35.92219244618255, "Pallor": 3.7838664790241543, "Pancytopenia": 2.709874113172724, "Parenteral nutrition associated liver disease": 407.845926029848, "Pathogen resistance": 42.36796436158664, "Pharyngitis": 6.453135242464469, "Pneumocystis jirovecii infection": 53.62121961048446, "Pneumonia": 2.266062260788043, "Pneumonia bacterial": 8.66790693928, "Product use in unapproved indication": 3.57854360702743, "Pseudomonas infection": 32.45388870286651, "Pulmonary mass": 6.206885209668884, "Rash maculo-papular": 9.530723214285532, "Renal failure": 2.358619087469169, "Renal impairment": 2.1031337202709337, "Respiratory distress": 2.833815884556932, "Respiratory failure": 6.748213216650827, "Scedosporium infection": 146.56999985542103, "Sepsis": 7.145030027663128, "Septic shock": 22.75027581385154, "Skin exfoliation": 3.5865656506980783, "Skin lesion": 5.240745149143815, "Skin necrosis": 6.663962703438559, "Stenotrophomonas infection": 150.69390469640794, "Streptococcal infection": 29.846691693096474, "Systemic candida": 100.571596874052, "Systemic mycosis": 97.9650393519305, "Tachypnoea": 2.3655419776914144, "Therapy non-responder": 9.569605529457633, "Toxic epidermal necrolysis": 13.241548939717738, "Toxic skin eruption": 4.486098956338444, "Transaminases increased": 4.133124347932673, "Treatment failure": 6.390981139810413, "Trichosporon infection": 237.0318399428488, "Unresponsive to stimuli": 3.595607314184063}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/244.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/244.json
index e5a7376ecc5..3314322072d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/244.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/244.json
@@ -1 +1 @@
-{"Diarrhoea ": 3.027232255904707, "Drug ineffective ": 2.681462655783291, "Drug resistance ": 49.459272413470735, "Off label use ": 3.251983126536617}
\ No newline at end of file
+{"Asthma": 37.69826354541946, "Cystic fibrosis": 976.0342656398344, "Drug ineffective": 2.165737121576069, "Dyspnoea": 6.372832773956869, "Infective pulmonary exacerbation of cystic fibrosis": 212.1742150583465, "Loss of personal independence in daily activities": 76.23873646718333, "Sleep disorder": 17.36845551502997, "Sleep disorder due to a general medical condition": 244.8819808223313, "Wheezing": 66.64900041729996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/245.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/245.json
index a9df0baf72a..85754902aa6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/245.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/245.json
@@ -1 +1 @@
-{"Abdominal distension ": 4.352179191775153, "Anaphylactic shock ": 14.998257129528922, "Blood calcium decreased ": 75.65609615152682, "Blood pressure decreased ": 4.6794770789746, "Bronchial hyperreactivity ": 729.1664017992144, "Drug hypersensitivity ": 4.252496186615889, "Erythema ": 2.2707003762949136, "Gastritis erosive ": 146.15983979393485, "Gastrointestinal haemorrhage ": 4.852642484573176, "Hepatic enzyme increased ": 6.024051232638052, "Hepatic function abnormal ": 12.85936133982243, "Muscle contractions involuntary ": 59.08739854093133, "Pulmonary alveolar haemorrhage ": 50.65044261465893}
\ No newline at end of file
+{"Drug ineffective": 16.541574184795856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/246.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/246.json
index ffc609ca371..73a427d972a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/246.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/246.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.001633262400938, "Abdominal pain upper ": 2.825999186704578, "Acute kidney injury ": 3.243527694605181, "Acute myeloid leukaemia ": 3.89436213905457, "Alanine aminotransferase increased ": 2.1685728101286235, "Anaphylactic reaction ": 3.2133895808402717, "Ankylosing spondylitis ": 4.722041006679708, "Antinuclear antibody positive ": 9.359985871974756, "Areflexia ": 8.565377256697056, "Arthritis ": 3.4023720723841264, "Arthropod bite ": 29.73875828067373, "Aspartate aminotransferase increased ": 2.302460070784132, "Blood alkaline phosphatase increased ": 2.764220085297792, "Blood chloride decreased ": 35.98760026635491, "Blood cholesterol increased ": 2.949996876689563, "Blood creatinine increased ": 6.124796620013664, "Blood potassium increased ": 3.4054342737739822, "Blood pressure systolic increased ": 3.245382052519473, "Blood sodium decreased ": 5.9992140814998285, "Blood urea decreased ": 21.961234813844317, "Blood urea increased ": 14.459985007011982, "Bone erosion ": 4.877755447253628, "Bradyphrenia ": 6.6292361675819365, "Brain scan abnormal ": 99.49787068154076, "Breath odour ": 25.438864669135505, "Bronchitis ": 5.018177366407232, "Bronchospasm ": 2.5304798082742943, "Bursitis ": 2.539527983175564, "C-reactive protein abnormal ": 3.04590867013248, "C-reactive protein increased ": 8.540027514261237, "Cerebral artery thrombosis ": 40.87677108402424, "Cholelithiasis ": 8.545022484868394, "Cognitive disorder ": 2.27215470601222, "Completed suicide ": 3.807880799507685, "Cystitis ": 5.055485003510575, "Delirium ": 2.1215650104732147, "Dementia Alzheimer's type ": 8.361621715817536, "Depersonalisation/derealisation disorder ": 13.375895333531496, "Drug eruption ": 2.752022883602856, "Drug hypersensitivity ": 3.596543828674449, "Drug interaction ": 5.336741643674915, "Drug intolerance ": 4.258210336661126, "Drug level increased ": 2.765427457674132, "Drug reaction with eosinophilia and systemic symptoms ": 4.862911813198087, "Enthesopathy ": 19.02226525195053, "Euglycaemic diabetic ketoacidosis ": 9.017105327801564, "Feeling jittery ": 10.70415470702378, "Femur fracture ": 6.088412729507736, "Fibromyalgia ": 5.942398000589662, "Fluid retention ": 5.198098434574378, "Foot deformity ": 3.4266784750706885, "Frequent bowel movements ": 3.591085642591316, "Gastric ulcer ": 2.0892452753969346, "Gastric ulcer haemorrhage ": 4.920746983024274, "Gastritis ": 4.653093891295279, "Gastrointestinal disorder ": 3.429791496373627, "Gastrooesophageal reflux disease ": 5.990069125001586, "Glaucoma ": 11.661514749400643, "Granuloma ": 9.121386530223866, "Hemiplegia ": 3.5062420895187807, "Hepatic steatosis ": 3.020415781021836, "Hip fracture ": 14.259902806493685, "Hypercalcaemia ": 4.4704417593419885, "Injury ": 5.686614070471255, "Joint range of motion decreased ": 2.138890373831185, "Lactic acidosis ": 3.737386679172201, "Laryngeal papilloma ": 624.8137397924909, "Liver function test abnormal ": 2.0804162203060703, "Lymphoedema ": 14.568999832387243, "Mast cell activation syndrome ": 18.30157064051844, "Metabolic acidosis ": 2.4527901017766607, "Metabolic alkalosis ": 24.363058398203624, "Migraine ": 2.1958011650187097, "Mitral valve incompetence ": 2.9873960499119057, "Mood altered ": 4.028828927031591, "Musculoskeletal disorder ": 2.941449501240041, "Myoclonus ": 2.6012558103548904, "Necrotising fasciitis ": 11.003400090320032, "Neuropathy peripheral ": 2.483398109829168, "Nitrite urine present ": 137.6881342924125, "Oliguria ": 3.5625772667323896, "Osteoarthritis ": 4.341118862648496, "Osteomyelitis ": 10.537403215361934, "Pemphigoid ": 2.08149580985475, "Phlebitis ": 9.44461549207107, "Psoriasis ": 2.4001400884204487, "Psoriatic arthropathy ": 2.99949996631996, "Purpura senile ": 986.279486566102, "Pyelonephritis acute ": 42.67883411725485, "Pyuria ": 29.260658892586427, "Quality of life decreased ": 3.693080239636271, "Renal artery stenosis ": 180.81444083313244, "Renal failure ": 2.5725264056595822, "Renal impairment ": 2.903683261686369, "Resorption bone increased ": 313.39479916085634, "Respiratory papilloma ": 1255.7592321339732, "Road traffic accident ": 7.658578886873633, "Sciatica ": 2.841236451837871, "Septic shock ": 2.082406160609268, "Serotonin syndrome ": 3.2729065572249314, "Skin lesion ": 2.9734036878540904, "Stent placement ": 7.906886363784955, "Superficial vein thrombosis ": 11.24812065123724, "Suspected suicide ": 5.70348602968559, "Syringomyelia ": 124.53901351863097, "Tarsal tunnel syndrome ": 529.9483074308141, "Thrombophlebitis ": 9.611690427339337, "Toxicity to various agents ": 3.122081017510918, "Tubulointerstitial nephritis ": 4.84254576135494, "Unresponsive to stimuli ": 9.024377805968376, "Upper gastrointestinal haemorrhage ": 2.533230213714392, "Urinary retention ": 3.729241956348934, "Vasculitis ": 20.17738209697164, "Vertigo positional ": 20.696113086729703, "Vestibular disorder ": 43.78855048876494, "Vitamin B12 decreased ": 34.9094075788953, "Vitamin D decreased ": 8.096134432081547, "White blood cell count decreased ": 2.3331872587715963}
\ No newline at end of file
+{"Drug ineffective": 3.0331455106217144, "Drug interaction": 5.223061880739655, "Drug resistance": 42.43951397031212, "Off label use": 4.350191446601156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/247.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/247.json
index 22b64be7594..0c3c073971c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/247.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/247.json
@@ -1 +1 @@
-{"Acne ": 3.01348220504698, "Actinic keratosis ": 6.821366774834101, "Acute graft versus host disease ": 6.2496369119336, "Acute graft versus host disease in intestine ": 4.672818127119497, "Acute pulmonary oedema ": 2.827860188455853, "Acute respiratory distress syndrome ": 5.898368638864629, "Adenocarcinoma ": 4.048724956322976, "Adenoviral haemorrhagic cystitis ": 87.85964759676507, "Adenovirus infection ": 9.60054174381196, "Agitation postoperative ": 71.77106590409363, "Agranulocytosis ": 11.07584577854706, "Amylase increased ": 3.8808583885688095, "Anaemia ": 2.5276359176465952, "Angiopathy ": 2.288810818238165, "Anogenital warts ": 6.157952096204422, "Anti-erythropoietin antibody negative ": 12.329698044569628, "Anuria ": 2.6743739069601165, "Aphthous ulcer ": 2.773493057180294, "Aplasia pure red cell ": 12.266874612439224, "Aplastic anaemia ": 2.924830084720364, "Arthritis bacterial ": 2.0156356750894986, "Ascites ": 2.31299651160958, "Aspergillus infection ": 10.040600147633402, "Atypical mycobacterial infection ": 7.596887484437276, "Autoimmune hepatitis ": 2.20094360978529, "Azotaemia ": 3.2794539122333117, "B-cell lymphoma ": 9.695254238961295, "BK virus infection ": 34.87374907063698, "Bacteraemia ": 4.637697081020913, "Bacterial infection ": 2.689296534430722, "Bacterial sepsis ": 6.091410745386403, "Basal cell carcinoma ": 9.791812639669704, "Bicytopenia ": 8.36955315532905, "Blood creatinine abnormal ": 2.56393174908664, "Blood creatinine increased ": 4.746346279625621, "Blood disorder ": 2.663199032723325, "Blood immunoglobulin G decreased ": 7.952161995789375, "Blood iron decreased ": 4.29736613128196, "Bone marrow failure ": 5.523301355179837, "Bowen's disease ": 39.87411581662972, "Brain abscess ": 9.962954724776148, "Brain herniation ": 5.0255576621374844, "Bronchial carcinoma ": 19.87842975688542, "Bronchial disorder ": 6.214608289540192, "Bronchiectasis ": 5.704708313311393, "Bronchiolitis ": 3.08275078665354, "Bronchopulmonary aspergillosis ": 12.89187524762836, "Burkitt's lymphoma ": 38.92957899242535, "COVID-19 pneumonia ": 5.825062368821206, "Cardiac hypertrophy ": 6.840302302485608, "Cardiac tamponade ": 2.307137312288034, "Cardiopulmonary failure ": 2.2918419425225465, "Cell death ": 3.772406021083672, "Central nervous system lymphoma ": 30.72718019611704, "Central nervous system vasculitis ": 8.689757655873368, "Cerebral ischaemia ": 2.92151928464957, "Cerebral toxoplasmosis ": 10.307633460347231, "Cervix carcinoma ": 4.43430947844659, "Cholangitis ": 4.221117363111109, "Cholecystitis chronic ": 6.386970314702105, "Cholestasis ": 2.83963586216232, "Chronic allograft nephropathy ": 38.45892521330973, "Colitis ": 3.379373499537601, "Colon cancer ": 2.538120705690844, "Coma ": 3.478121286310658, "Complications of transplanted kidney ": 27.68925373464343, "Congenital aplasia ": 4.829780306012806, "Congestive hepatopathy ": 6.517876692859724, "Cryptococcosis ": 16.187594349916083, "Cushingoid ": 4.773691828589302, "Cystitis haemorrhagic ": 8.66296791371324, "Cystitis viral ": 30.51272700097987, "Cytomegalovirus chorioretinitis ": 13.930709833090246, "Cytomegalovirus colitis ": 27.404357297865914, "Cytomegalovirus enterocolitis ": 57.322939558640336, "Cytomegalovirus gastritis ": 47.88151024864813, "Cytomegalovirus gastroenteritis ": 46.21942754099628, "Cytomegalovirus hepatitis ": 22.83854452966295, "Cytomegalovirus infection ": 61.557429292983485, "Cytomegalovirus infection reactivation ": 9.14950864387576, "Cytomegalovirus syndrome ": 82.38600561826152, "Cytomegalovirus test positive ": 87.83746432207568, "Cytomegalovirus viraemia ": 48.288812454449406, "Cytopenia ": 2.9785997732511453, "Delayed graft function ": 34.52110111674956, "Dermatomyositis ": 3.8825634267607088, "Dermoid cyst ": 28.709174584390997, "Device related infection ": 2.03200452509942, "Diabetes mellitus ": 2.5526158166559805, "Diarrhoea ": 2.205666135923112, "Diffuse alveolar damage ": 10.577247903228676, "Diffuse large B-cell lymphoma ": 17.543636239494596, "Disseminated cryptococcosis ": 22.542643091369747, "Disseminated intravascular coagulation ": 3.873633575106857, "Disseminated tuberculosis ": 12.254899719968757, "Diverticular perforation ": 3.966554385145044, "Drug level decreased ": 5.639861650525777, "Drug level fluctuating ": 12.600813457827252, "Drug level increased ": 3.395631857025814, "Drug specific antibody absent ": 15.100755960136024, "Duodenal ulcer ": 2.6607221505039784, "Encephalitis ": 2.920065111984814, "Encephalitis cytomegalovirus ": 14.563323764016156, "Encephalitis herpes ": 12.591439968534626, "Encephalitis viral ": 5.906530671507574, "Encephalopathy ": 2.835192700007331, "Endocarditis ": 5.708008270847819, "Endotracheal intubation ": 2.055885020516996, "Enteritis ": 2.672440989504256, "Enteritis infectious ": 6.924872655561069, "Enterococcal infection ": 3.401247265810036, "Enterocolitis ": 4.900493811886931, "Epstein-Barr viraemia ": 8.169539732380766, "Epstein-Barr virus antibody positive ": 18.95579463412055, "Epstein-Barr virus associated lymphoma ": 43.23447531068427, "Epstein-Barr virus associated lymphoproliferative disorder ": 33.48511724642814, "Epstein-Barr virus infection ": 24.436701442912987, "Epstein-Barr virus infection reactivation ": 5.893489588889363, "Epstein-Barr virus test positive ": 56.52770006020345, "Escherichia infection ": 6.144291053759965, "Escherichia urinary tract infection ": 10.246265194721971, "External auditory canal atresia ": 97.15114321342358, "Faeces soft ": 5.716870511229147, "Fistula ": 2.123860260213246, "Focal segmental glomerulosclerosis ": 17.13933981185598, "Fungaemia ": 7.542394900674092, "Fungal infection ": 2.497603907609301, "Fungal skin infection ": 5.553304529585308, "Furuncle ": 2.562074973882546, "Gastric ulcer ": 2.777072423598667, "Gastric ulcer haemorrhage ": 2.2594542238576354, "Gastroenteritis ": 5.307408492740439, "Gastroenteritis norovirus ": 8.823006580444792, "Gastrointestinal motility disorder ": 2.145583538463665, "Gastrointestinal perforation ": 2.548105606744804, "Gastrointestinal toxicity ": 2.9074255181370234, "Gastrooesophageal reflux disease ": 3.660109447625509, "Gingival hypertrophy ": 5.944168645815715, "Glomerulonephritis ": 3.097694837447677, "Glomerulonephritis membranoproliferative ": 14.06277910495802, "Glomerulonephritis membranous ": 6.091074106028458, "Graft versus host disease ": 7.418064076304272, "Graft versus host disease in gastrointestinal tract ": 4.485700010727057, "Graft versus host disease in lung ": 16.736195093747018, "Graft versus host disease in skin ": 3.4418839790780487, "Granulocytopenia ": 3.452063718030019, "Groin infection ": 23.92621648169678, "H1N1 influenza ": 10.906384077074092, "Haemodialysis ": 5.149641458745206, "Haemodynamic instability ": 2.0857970678550046, "Haemoglobin abnormal ": 2.3802088500948595, "Haemoglobin increased ": 2.1956183740138435, "Haemolysis ": 3.0605721059360813, "Haemolytic anaemia ": 3.0735853888085813, "Haemolytic uraemic syndrome ": 11.023874493575608, "Haemophagocytic lymphohistiocytosis ": 6.778601802457466, "Haemorrhoidal haemorrhage ": 2.311765813871215, "Heart transplant rejection ": 23.19021462318545, "Hepatitis B ": 7.075289590893658, "Hepatitis C ": 2.780995653242304, "Hepatitis cholestatic ": 2.1783549978793344, "Herpes simplex ": 3.036142562647808, "Herpes virus infection ": 4.878012250783681, "Herpes zoster ": 2.003161757855574, "Herpes zoster disseminated ": 19.49743717543661, "Herpes zoster meningoencephalitis ": 23.729785859800128, "Hidradenitis ": 5.101948365812859, "Hodgkin's disease ": 3.1816551009501386, "Human herpes virus 6 serology positive ": 34.30181760294619, "Human herpesvirus 6 encephalitis ": 37.357401334036176, "Human herpesvirus 6 infection ": 7.231179077667551, "Human polyomavirus infection ": 45.997681295795374, "Hydronephrosis ": 6.18181151048279, "Hyperparathyroidism ": 7.7063217209016415, "Hyperuricaemia ": 8.262234278178871, "Hypogammaglobulinaemia ": 9.929377026422848, "Hypomagnesaemia ": 2.350438161000631, "Hypoproteinaemia ": 5.555024966948186, "IgA nephropathy ": 8.20504393231869, "Ileus ": 3.608336993972476, "Ileus paralytic ": 2.5204144742580685, "Immunodeficiency ": 2.478989542550925, "Immunosuppressant drug level decreased ": 44.13018579337084, "Immunosuppressant drug level increased ": 18.36048461702587, "Immunosuppression ": 4.006832116069288, "Impaired gastric emptying ": 2.031749997539881, "Incorrect route of product administration ": 2.466737205296296, "Increased bronchial secretion ": 2.626672810439041, "Infection ": 2.4627052796915785, "Infection in an immunocompromised host ": 54.31946965833135, "Infection parasitic ": 20.291127400644083, "Intentional product use issue ": 8.537142438057458, "Interstitial lung disease ": 2.1146259981820386, "Intestinal ischaemia ": 2.2717768058667147, "Intestinal perforation ": 3.032883335114489, "Intestinal villi atrophy ": 21.864150991807485, "JC virus infection ": 18.16431770930829, "Kaposi's sarcoma ": 17.05872921082625, "Kidney fibrosis ": 4.338562430805784, "Kidney transplant rejection ": 76.43006948542025, "Klebsiella infection ": 3.8202099405616106, "Klebsiella sepsis ": 12.720291964196132, "Kussmaul respiration ": 37.6837700343522, "Large intestinal ulcer ": 6.621788692058152, "Large intestine perforation ": 3.4359483036397087, "Left ventricular dysfunction ": 2.131584345210736, "Leukoencephalopathy ": 5.681425848949701, "Leukopenia ": 8.923749910207928, "Liver abscess ": 5.329942300116247, "Liver function test abnormal ": 2.712470878928291, "Liver transplant rejection ": 29.554386484103908, "Lung adenocarcinoma ": 3.398607704151845, "Lung disorder ": 3.921506847872158, "Lung transplant rejection ": 24.82839929098712, "Lupus nephritis ": 13.838734601732185, "Lymphadenectomy ": 7.5880545887889586, "Lymphocele ": 65.92093004617628, "Lymphoma ": 9.166852715532633, "Lymphopenia ": 5.901356450246229, "Lymphoproliferative disorder ": 25.38253063793229, "Macule ": 2.3005229126089555, "Malabsorption ": 2.306561090966368, "Meningitis ": 2.1292880044485374, "Meningitis cryptococcal ": 18.6082643096074, "Meningitis viral ": 7.48594216551238, "Metastases to lymph nodes ": 2.5345057027326523, "Microtia ": 62.236788757969975, "Mouth ulceration ": 2.3377251739106857, "Mucopolysaccharidosis I ": 250.24972189929596, "Mucormycosis ": 6.7687935101413, "Multiple organ dysfunction syndrome ": 3.8427621192294414, "Myasthenia gravis ": 2.7640399540590344, "Myelitis ": 3.2271846411120104, "Myelitis transverse ": 3.3311080675610008, "Myelodysplastic syndrome with single lineage dysplasia ": 13.780979705435357, "Necrosis ": 2.028655164016316, "Neoplasm skin ": 9.442541191957403, "Nephrectomy ": 3.7230717587577207, "Nephropathy toxic ": 5.056530041436114, "Nephrotic syndrome ": 5.160972643255575, "Neutropenia ": 4.26069146430053, "No adverse event ": 2.4419241185178486, "Nocardiosis ": 16.590317693593732, "Non-Hodgkin's lymphoma ": 5.223905296077697, "Obliterative bronchiolitis ": 6.987507970683218, "Oesophageal candidiasis ": 2.2737530876965963, "Oesophageal ulcer ": 3.877766852691498, "Oesophagitis ": 2.484503976516243, "Off label use ": 3.220427335712142, "Oliguria ": 2.090245901097928, "Opportunistic infection ": 9.029254075926865, "Osteitis ": 6.060786009989613, "Osteomyelitis ": 2.473218546425137, "Otitis media ": 2.563018743769575, "Ovarian cyst ": 10.531921526894331, "Oxygen therapy ": 3.78583408742792, "PASH syndrome ": 555.7050803405959, "Pancreatitis ": 2.4164639259746905, "Pancreatitis acute ": 2.8882362560647774, "Pancreatitis necrotising ": 8.09783630329994, "Pancytopenia ": 8.208864627071813, "Paranasal sinus abscess ": 275.8342741665905, "Parvovirus B19 infection ": 17.338062751951334, "Parvovirus B19 test positive ": 68.17961602160781, "Peritonitis ": 5.079260484300982, "Pleural effusion ": 2.033584905738471, "Pneumatosis intestinalis ": 3.451755876689333, "Pneumococcal sepsis ": 14.769015900121117, "Pneumocystis jirovecii infection ": 22.760208417529224, "Pneumocystis jirovecii pneumonia ": 17.860818541303043, "Pneumonia ": 3.336764081476845, "Pneumonia aspiration ": 8.844958478506454, "Pneumonia bacterial ": 3.974334792264212, "Pneumonia cryptococcal ": 45.17720101863723, "Pneumonia cytomegaloviral ": 22.29409306475558, "Pneumonia fungal ": 7.279963775959679, "Pneumonia klebsiella ": 6.152738908644116, "Pneumonia legionella ": 7.932109869024526, "Pneumonia pneumococcal ": 11.665934384057923, "Pneumonia pseudomonal ": 6.168940989865584, "Pneumonia viral ": 3.573527053201716, "Polyomavirus-associated nephropathy ": 204.99569829209383, "Post transplant lymphoproliferative disorder ": 74.24318279991152, "Posterior reversible encephalopathy syndrome ": 7.782395812293387, "Postoperative wound infection ": 3.968948297810744, "Progressive multifocal leukoencephalopathy ": 32.34308123787983, "Protein urine present ": 2.708384754262631, "Proteinuria ": 4.029639456439384, "Pseudomembranous colitis ": 4.966337751243146, "Pseudomonal sepsis ": 4.085297372411056, "Pseudomonas infection ": 4.114204383274852, "Pulmonary alveolar haemorrhage ": 3.9258014252236095, "Pulmonary fibrosis ": 3.012345155079541, "Pulmonary tuberculosis ": 11.212835071791746, "Pyelonephritis ": 9.60698763457576, "Pyelonephritis acute ": 9.882029668808537, "Pyoderma ": 19.34637327101921, "Pyuria ": 9.160431090205083, "Rales ": 3.083760314087169, "Red blood cell sedimentation rate abnormal ": 3.028318415208844, "Renal artery stenosis ": 10.28885856057908, "Renal impairment ": 3.4275686868485584, "Renal transplant failure ": 29.06729677770697, "Renal tubular atrophy ": 12.533345178055896, "Renal tubular disorder ": 5.9969537576087, "Renal tubular necrosis ": 4.146296729341907, "Respiratory failure ": 2.4776996901462667, "Respiratory tract congestion ": 3.065839417299037, "Respiratory tract infection ": 2.0348538575716737, "Scleroderma ": 4.643109913595381, "Sepsis ": 4.377377921705844, "Septic shock ": 4.472381845577724, "Serum sickness ": 5.164591760727684, "Skin cancer ": 8.499873104532156, "Skin papilloma ": 4.7010893277027, "Skin ulcer ": 2.135162797500428, "Sleep disorder due to general medical condition, insomnia type ": 8.224193024830127, "Small intestinal obstruction ": 3.902657034682522, "Squamous cell carcinoma ": 12.475674599889643, "Squamous cell carcinoma of skin ": 15.513792599854716, "Staphylococcal bacteraemia ": 3.0281214940116405, "Staphylococcal infection ": 3.069252521466123, "Staphylococcal sepsis ": 3.0082401415634226, "Steroid diabetes ": 19.06829886451219, "Subcutaneous abscess ": 2.3128326800366144, "Systemic inflammatory response syndrome ": 2.7147943317151264, "Systemic scleroderma ": 10.574153652848608, "Therapy partial responder ": 4.381579832242541, "Thrombocytopenia ": 2.034912854989217, "Thrombotic microangiopathy ": 18.18281222727173, "Thrombotic thrombocytopenic purpura ": 3.323645534606744, "Toxoplasmosis ": 20.368267377088618, "Transplant dysfunction ": 106.2384847158186, "Transplant failure ": 14.736080887172353, "Transplant rejection ": 70.06709724646423, "Tuberculosis ": 3.95196105175824, "Upper respiratory tract inflammation ": 9.699140790352994, "Ureteric stenosis ": 22.03720358569052, "Urinary tract infection ": 4.037406104940371, "Urinary tract infection bacterial ": 6.215936288411734, "Urinary tract infection viral ": 75.76259888905591, "Urine output decreased ": 2.9620786768585, "Urosepsis ": 4.798199892531818, "Uterine cancer ": 3.166509764761328, "Varicella ": 3.2599324921639803, "Varicella zoster pneumonia ": 38.05272509512184, "Varicella zoster virus infection ": 5.440751493405972, "Venoocclusive liver disease ": 2.8393305411658143, "Viral haemorrhagic cystitis ": 26.403661823082818, "Viral infection ": 4.294545424283374, "Vulval disorder ": 16.504554685153046, "White blood cell count decreased ": 2.2764420439661515, "Wound dehiscence ": 6.658772755013069}
\ No newline at end of file
+{"General physical health deterioration": 23.64948355769369, "Hypophagia": 129.91825049650234, "Off label use": 2.9457618106591665, "Placental insufficiency": 1995.0411285213304, "Staphylococcal infection": 101.24909970862343, "Thrombocytopenia": 11.736474983171036, "Transaminases increased": 46.20278531343868, "Treatment failure": 35.35237306579503}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/248.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/248.json
index 7850e0934d0..d35029df9eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/248.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/248.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.213128316038894, "Aggression ": 3.2454797414966223, "Alanine aminotransferase increased ": 5.06821736970525, "Aspartate aminotransferase increased ": 4.224863391685897, "Balance disorder ": 2.378210072975129, "Blood HIV RNA increased ": 84.61754071722183, "Blood creatine phosphokinase increased ": 6.3268085511644445, "Blood creatinine increased ": 2.358429670540305, "Condition aggravated ": 2.139694542240019, "Depression ": 2.146823113076952, "Drug interaction ": 2.8602262928930893, "Drug resistance ": 10.89045383743329, "Dysphagia ": 2.249869611395156, "Enanthema ": 133.48611436397306, "Gamma-glutamyltransferase increased ": 5.677064344594642, "Glaucoma ": 18.365198130685133, "Hepatic cytolysis ": 6.362524548674013, "Hepatic enzyme increased ": 3.340333528945695, "Hepatitis B reactivation ": 37.90994644162344, "Immune reconstitution inflammatory syndrome ": 39.17421059660683, "Ischaemic stroke ": 13.789760203676, "Jaundice ": 5.3434896740701445, "Lipids increased ": 97.2135798576956, "Live birth ": 17.892309315246393, "Malaria ": 314.199920891648, "Muscle twitching ": 5.826827876328659, "Nervous system disorder ": 15.924331632167846, "Oedema ": 2.5430580199616366, "Oedema peripheral ": 2.027070091307062, "Pancytopenia ": 2.8369679267689256, "Pathogen resistance ": 34.94696541122213, "Petit mal epilepsy ": 38.55345919083141, "Prinzmetal angina ": 147.42765613363318, "Rash maculo-papular ": 5.948979686090576, "Renal impairment ": 3.5996340161768408, "Renal tubular necrosis ": 24.838953255165272, "Treatment noncompliance ": 16.09923868125667, "Viral mutation identified ": 91.43272044930563, "Virologic failure ": 42.95093565629815, "Vitreous haemorrhage ": 76.49031122004548}
\ No newline at end of file
+{"Diarrhoea": 3.027206993628847, "Drug ineffective": 2.681442834813086, "Drug resistance": 49.459272413470735, "Off label use": 3.251855050228894}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/249.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/249.json
index a410c35abca..adb115ce98c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/249.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/249.json
@@ -1 +1 @@
-{"Coma scale abnormal ": 449.80007570716, "Drug interaction ": 13.07460950115554}
\ No newline at end of file
+{"Abdominal distension": 4.352179191775153, "Anaphylactic shock": 14.998257129528922, "Blood calcium decreased": 75.65609615152682, "Blood pressure decreased": 4.679325223171978, "Bronchial hyperreactivity": 729.1664017992144, "Drug hypersensitivity": 4.252496186615889, "Erythema": 2.270678167859293, "Gastritis erosive": 146.00098610311133, "Gastrointestinal haemorrhage": 4.852642484573176, "Hepatic enzyme increased": 6.024051232638052, "Hepatic function abnormal": 12.85936133982243, "Muscle contractions involuntary": 59.08739854093133, "Pulmonary alveolar haemorrhage": 50.65044261465893}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/25.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/25.json
index f665c7b3398..8dcc182a741 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/25.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/25.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 10.639278442296764, "Abdominal distension ": 3.04602412329072, "Abdominal pain upper ": 3.411225519294096, "Adjustment disorder with depressed mood ": 48.810600898538105, "Adrenal insufficiency ": 3.646115471151065, "Adverse drug reaction ": 7.10706464012192, "Adverse event ": 4.230755138928314, "Adverse reaction ": 20.490149599971677, "Alanine aminotransferase abnormal ": 9.996477696392612, "Allergy to chemicals ": 5.555265291000941, "Alopecia ": 9.90363161838252, "Amaurosis fugax ": 11.048218284906964, "Amnesia ": 4.040362564710142, "Ankle arthroplasty ": 86.29912269991883, "Anti-cyclic citrullinated peptide antibody ": 115.09776496810495, "Anti-cyclic citrullinated peptide antibody positive ": 50.13069383568188, "Antibody test positive ": 12.929014598384825, "Anticipatory anxiety ": 18.698497387935017, "Antinuclear antibody positive ": 3.389627332397746, "Arthritis ": 4.966033072458957, "Arthropathy ": 22.016648906359464, "Autoimmune disorder ": 19.82046646087161, "Back disorder ": 11.189783138012508, "Back injury ": 20.97498451926479, "Basal cell carcinoma ": 6.918442928061056, "Blepharospasm ": 31.39548064847843, "Blister ": 10.413889187908827, "Blood cholesterol ": 13.545587801759297, "Blood cholesterol increased ": 20.70183518423435, "Blood iron abnormal ": 2.4794232146282837, "Blood parathyroid hormone decreased ": 29.745151528815597, "Body height below normal ": 44.041831875841744, "Bone density increased ": 22.676199217951705, "Bone erosion ": 19.76518918226552, "Breast cancer stage II ": 125.36099498307053, "Breast cancer stage III ": 98.71541496978408, "Bronchiectasis ": 7.462814001381392, "Burns second degree ": 23.40455271813838, "Bursitis ": 30.92854617951778, "C-reactive protein ": 107.44238709473872, "C-reactive protein abnormal ": 48.15333941329076, "C-reactive protein increased ": 12.525830480978518, "Cardiac murmur ": 2.931889310545699, "Catarrh ": 10.963822457919322, "Chronic sinusitis ": 21.033582186701448, "Coeliac disease ": 21.00457445841432, "Colitis ": 3.715221453936108, "Colitis ulcerative ": 7.306642473457567, "Condition aggravated ": 4.790480850229275, "Confusional state ": 4.103876241969562, "Congenital anomaly ": 2.0629393666227376, "Contraindicated product administered ": 18.234577497796696, "Contraindication to vaccination ": 4.413695800156847, "Contusion ": 4.250777413430337, "Crepitations ": 2.537939052994054, "Crohn's disease ": 4.658734345125329, "Cushingoid ": 3.2172758626918685, "Dactylitis ": 2.575129266358245, "Death neonatal ": 2.1558890440770555, "Deep vein thrombosis postoperative ": 100.9902381604967, "Deformity ": 7.511963735757865, "Delirium ": 3.8279048727519664, "Depression ": 2.139216839547317, "Disability ": 11.01487995314442, "Discomfort ": 12.412892264846462, "Dislocation of vertebra ": 66.0487093083409, "Disseminated tuberculosis ": 2.220065711603383, "Drug hypersensitivity ": 6.774836574416705, "Drug ineffective ": 2.319922583054951, "Drug intolerance ": 10.019198583773363, "Drug specific antibody ": 8.83841717855985, "Drug specific antibody present ": 11.13210291171388, "Drug tolerance ": 24.904701784995314, "Drug tolerance decreased ": 25.17719076380436, "Drug-induced liver injury ": 4.09110805089593, "Dry mouth ": 3.87096804806446, "Duodenal ulcer perforation ": 45.01902211086765, "Dyspepsia ": 5.6285399700240974, "Ear infection ": 4.58662260258917, "Ear injury ": 15.368706045196216, "Enthesopathy ": 24.6243911596362, "Exostosis ": 10.687019010380975, "Exposure during pregnancy ": 4.545423019527303, "Eye injury ": 24.461604664205257, "Facet joint syndrome ": 88.47905841953924, "Faecal calprotectin increased ": 6.360529374666531, "Fear of injection ": 8.085083176756944, "Female genital tract fistula ": 23.6873120117876, "Fibromyalgia ": 19.820756048712404, "Finger deformity ": 24.87681844314307, "Folliculitis ": 26.28057589893454, "Foot deformity ": 11.47907806571818, "Foot operation ": 8.578135568763129, "Fracture delayed union ": 22.766146766580864, "Frequent bowel movements ": 12.153282138137984, "Gait inability ": 4.023355525729077, "Gastroenteritis viral ": 5.794775056059652, "Gastrointestinal bacterial overgrowth ": 3.5014332224631324, "Gastrointestinal disorder ": 4.450290548625008, "General physical health deterioration ": 6.285952389807419, "Gingival pain ": 4.39560898576439, "Glossodynia ": 25.241274263524, "Granuloma ": 3.106849179819504, "Granuloma skin ": 26.57864400273933, "Grip strength ": 15.109989719144576, "Grip strength decreased ": 19.0846999528507, "Groin abscess ": 2.570070518462994, "Haematochezia ": 3.3904797833235825, "Hand deformity ": 32.18466224308178, "Helicobacter infection ": 32.68494344561906, "Hepatic cirrhosis ": 2.612448250737179, "Hepatic enzyme increased ": 5.5895556775546815, "Hepatitis ": 2.3652135048073237, "Hepatosplenic T-cell lymphoma ": 6.724396334597728, "Hidradenitis ": 8.452485382796315, "Hip arthroplasty ": 6.0346478264545, "Human anti-human antibody test ": 35.954877412028665, "Human antichimeric antibody positive ": 68.83068999167335, "Hyperadrenocorticism ": 13.86242020610056, "Hypercalcaemia ": 3.883461725655418, "Hypercholesterolaemia ": 8.361792741822832, "Hypersensitivity ": 2.7348615230126083, "Hypocalcaemia ": 3.44490351741787, "Hypopnoea ": 5.766515764976311, "Ileal stenosis ": 4.054272166894666, "Ill-defined disorder ": 9.970955755179384, "Immunodeficiency ": 4.972039269810835, "Impaired healing ": 12.113187967944675, "Impaired quality of life ": 8.915119902712986, "Impaired work ability ": 2.08204229068418, "Infection ": 3.650537269877672, "Inflammation ": 6.238152895063161, "Infusion related reaction ": 17.138512223169908, "Infusion site reaction ": 7.183793956895422, "Injury ": 10.371579466868871, "Intentional product use issue ": 7.699286925355375, "Investigation abnormal ": 2.370065114815082, "Iodine allergy ": 3.762866126024607, "Irritable bowel syndrome ": 10.958487464663094, "Joint ankylosis ": 6.169708205474051, "Joint destruction ": 66.2930447971063, "Joint dislocation ": 5.663090527123753, "Joint effusion ": 2.681766553925517, "Joint laxity ": 4.350782953810553, "Joint range of motion decreased ": 12.644413154790112, "Joint stiffness ": 3.236302820919654, "Joint swelling ": 5.042472328597467, "Juvenile idiopathic arthritis ": 7.35401750983562, "Knee arthroplasty ": 5.03561976091076, "Laryngitis ": 5.005427635553094, "Limb deformity ": 4.802418510331047, "Lip dry ": 9.193255044639187, "Live birth ": 6.8740139502629525, "Liver function test increased ": 3.2086332847359973, "Liver injury ": 8.72996719719374, "Loose body in joint ": 47.79142692684376, "Loss of personal independence in daily activities ": 2.2106161508344417, "Loss of therapeutic response ": 2.5010924033491966, "Lower limb fracture ": 2.3123839575932377, "Lower respiratory tract infection ": 2.6706352106786118, "Lupus vulgaris ": 128.471314006873, "Lupus-like syndrome ": 6.555661583689183, "Macular degeneration ": 19.968526399944903, "Maternal exposure during pregnancy ": 6.0895209360909455, "Maternal exposure timing unspecified ": 3.971321771847468, "Mean cell haemoglobin decreased ": 6.810342603969291, "Mean cell volume decreased ": 5.876550718248341, "Mean platelet volume decreased ": 8.927738169431281, "Medication error ": 2.133456754265262, "Mobility decreased ": 4.761835202629054, "Muscle injury ": 8.775946971078632, "Musculoskeletal deformity ": 27.88049298956776, "Musculoskeletal disorder ": 3.239464489598455, "Musculoskeletal pain ": 3.177389417540368, "Musculoskeletal stiffness ": 2.7490435485845675, "Nail disorder ": 2.028716930403175, "Non-alcoholic fatty liver ": 4.280030763089571, "Noninfective gingivitis ": 2.4518935993055657, "Obesity ": 7.523893958818003, "Onychomadesis ": 35.376428467098215, "Onychomycosis ": 32.21783678183156, "Oral candidiasis ": 7.326698403738829, "Oral discomfort ": 2.739430219706182, "Osteoarthritis ": 3.172244840762692, "Osteoporotic fracture ": 3.531075424269411, "Panniculitis ": 8.630721533950622, "Paraesthesia oral ": 4.87108335621482, "Parathyroid disorder ": 11.73022432182549, "Parathyroidectomy ": 5.252258124854462, "Pemphigus ": 24.43070073020857, "Pericarditis ": 5.686499454917296, "Peripheral venous disease ": 22.15822582565768, "Pityriasis rubra pilaris ": 4.959263203251201, "Plasmablastic lymphoma ": 4.401785795732926, "Polyarthritis ": 5.7244963659828425, "Porphyria acute ": 5.591640668937998, "Pregnancy ": 2.08631776103997, "Prescribed overdose ": 2.6491991862380067, "Prescribed underdose ": 5.6176672053528085, "Procedural pain ": 20.61423495256972, "Proctitis ": 20.477085463132635, "Product label confusion ": 3.917535318493809, "Product temperature excursion issue ": 12.397406859206022, "Product use issue ": 5.208295880848833, "Psoriatic arthropathy ": 15.646597914898898, "Pulmonary fibrosis ": 5.0953882977752825, "Pustular psoriasis ": 2.514843018978814, "Pyoderma gangrenosum ": 2.84020242287921, "Radiculopathy ": 16.81527406706779, "Rectal haemorrhage ": 3.683919967036604, "Red blood cell sedimentation rate ": 14.775003261985889, "Red blood cell sedimentation rate abnormal ": 13.83199416613156, "Red blood cell sedimentation rate increased ": 4.041460858897409, "Red cell distribution width decreased ": 4.9529041049976215, "Retinitis ": 25.667361731257184, "Rheumatic fever ": 37.43060745846528, "Rheumatoid arthritis ": 7.229524863126858, "Rheumatoid factor positive ": 24.497784720931406, "Rheumatoid lung ": 9.477363536977917, "Rheumatoid nodule ": 4.629907498506006, "Road traffic accident ": 2.0337425552645043, "Sacroiliitis ": 6.4446554417178525, "Sciatica ": 3.631989707946509, "Seronegative arthritis ": 2.287553969472409, "Sinusitis ": 2.3062913467358004, "Sleep disorder due to general medical condition, insomnia type ": 6.681113163450791, "Spondyloarthropathy ": 10.83815548455303, "Steroid dependence ": 60.33228946518284, "Stomatitis ": 2.2114815741302283, "Swelling ": 3.6874795842126256, "Swollen joint count increased ": 25.49882592969712, "Synovitis ": 10.90125229090614, "Systemic lupus erythematosus ": 12.65047627171225, "Takayasu's arteritis ": 7.962753158463122, "Tenosynovitis ": 4.048562447724527, "Terminal ileitis ": 3.152172183462422, "Therapeutic product effect decreased ": 5.862955601167547, "Therapeutic product effect incomplete ": 3.4474201390167263, "Therapy non-responder ": 2.5176123284837675, "Treatment failure ": 5.551489136058239, "Type 2 diabetes mellitus ": 4.1042977634987, "Ulcer haemorrhage ": 4.077708178465914, "Urinary tract disorder ": 3.202560074789494, "Vaginal discharge ": 11.706471024861564, "Vaginal flatulence ": 26.04619129250113, "Vulval disorder ": 2.6975547463442684, "Whipple's disease ": 9.21635320977166, "Wound ": 13.090026825490408, "Wound complication ": 2.285272100546647, "Wound infection ": 10.921638155910475, "X-ray abnormal ": 9.016508119717496}
\ No newline at end of file
+{"Abortion induced": 7.237452877445067, "Abscess": 8.31855174511245, "Accidental overdose": 4.187485096400902, "Anuria": 4.604732110523533, "Arteriosclerosis coronary artery": 16.767488677491823, "Asphyxia": 12.634981242525924, "Blood glucose abnormal": 7.130757524787525, "Blood glucose decreased": 8.137205291976633, "Blood glucose fluctuation": 35.44021146286171, "Blood glucose increased": 18.67705150122187, "COVID-19 pneumonia": 10.448021533724388, "Cardiac disorder": 2.652406787140249, "Coma": 2.5153928242969834, "Condition aggravated": 7.612795996865404, "Dehiscence": 771.4370357557297, "Dermatitis allergic": 2.4796739850653986, "Device failure": 44.81649003706615, "Device issue": 9.381893517130438, "Device malfunction": 13.21741262764763, "Diabetes mellitus inadequate control": 11.34641026278777, "Diabetic coma": 58.117475163788185, "Diabetic foot": 22.56599025086869, "Diabetic hyperglycaemic coma": 121.4428010700712, "Diabetic ketoacidosis": 6.956915140463213, "Drug hypersensitivity": 4.199132643288808, "Exposure during pregnancy": 3.7082263932184256, "Extra dose administered": 8.751528734546733, "Foetal exposure during pregnancy": 2.909382303100484, "Glycosylated haemoglobin increased": 10.672403628470969, "Haematocrit decreased": 2.8540721932572395, "Hepatic steatosis": 4.572345449220898, "Hyperglycaemia": 21.794126062401197, "Hyperinsulinaemic hypoglycaemia": 48.3005349599956, "Hypoglycaemia": 48.13772001110835, "Hypoglycaemic coma": 64.03942587244862, "Hypoglycaemic seizure": 29.959368756581004, "Hypoglycaemic unconsciousness": 29.317153712174655, "Hypothermia": 4.73765141438557, "Incorrect dose administered": 3.402394032769598, "Incorrect dose administered by device": 27.30343797426918, "Injection site abscess": 19.445792850003738, "Injection site ulcer": 72.07452070892896, "Insulin resistance": 21.031783213450478, "Ketoacidosis": 10.444151458625472, "Lactic acidosis": 2.5535677290363106, "Lipodystrophy acquired": 18.486994368373526, "Loss of consciousness": 2.9668160884171493, "Medication error": 4.693144017178753, "Nikolsky's sign": 104.10362586681872, "Pneumocystis jirovecii pneumonia": 11.995337305180469, "Premature baby": 4.277366932055089, "Premature delivery": 7.798892225614347, "Product administration error": 3.961220174426101, "Product leakage": 7.336652671392606, "Product physical issue": 7.995969630384268, "Product quality issue": 10.088048977106665, "Product storage error": 8.633175288682734, "Pulmonary infarction": 53.37005354475439, "Respiratory alkalosis": 90.13850669911108, "Respiratory failure": 24.603194314622364, "SARS-CoV-2 test positive": 6.7637408373775605, "Shock hypoglycaemic": 342.5580365368121, "Skin erosion": 13.122778890193228, "Sopor": 7.838605003762248, "Stevens-Johnson syndrome": 4.597069127557772, "Superficial vein thrombosis": 9.912164278037086, "Supraventricular tachycardia": 11.643428819285306, "Toxic epidermal necrolysis": 14.423900937408742, "Toxic skin eruption": 2.936809930335765, "Treatment noncompliance": 3.8613732750715655, "Type IV hypersensitivity reaction": 35.18247295899008, "Wrong product administered": 16.329528189158147, "Wrong technique in product usage process": 3.2197153790718134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/250.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/250.json
index d0f1955cc43..6b2ef18fcb8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/250.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/250.json
@@ -1 +1 @@
-{"Foetal exposure during pregnancy ": 39.82482979404303, "Foetal growth restriction ": 396.3152677772589}
\ No newline at end of file
+{"Abdominal discomfort": 2.001633262400938, "Abdominal pain upper": 2.825999186704578, "Acute kidney injury": 3.243527694605181, "Acute myeloid leukaemia": 3.89436213905457, "Alanine aminotransferase increased": 2.1685728101286235, "Anaphylactic reaction": 3.2133211938604527, "Ankylosing spondylitis": 4.722041006679708, "Antinuclear antibody positive": 9.359985871974756, "Areflexia": 8.565377256697056, "Arthritis": 3.4023720723841264, "Arthropod bite": 29.73875828067373, "Aspartate aminotransferase increased": 2.302460070784132, "Blood alkaline phosphatase increased": 2.764220085297792, "Blood chloride decreased": 35.98760026635491, "Blood cholesterol increased": 2.949996876689563, "Blood creatinine increased": 6.124796620013664, "Blood potassium increased": 3.4054342737739822, "Blood pressure systolic increased": 3.245382052519473, "Blood sodium decreased": 5.9992140814998285, "Blood urea decreased": 21.961234813844317, "Blood urea increased": 14.459985007011982, "Bone erosion": 4.877755447253628, "Bradyphrenia": 6.6292361675819365, "Brain scan abnormal": 99.49787068154076, "Breath odour": 25.438864669135505, "Bronchitis": 5.01787581393667, "Bronchospasm": 2.5304798082742943, "Bursitis": 2.539527983175564, "C-reactive protein abnormal": 3.04590867013248, "C-reactive protein increased": 8.540027514261237, "Cerebral artery thrombosis": 40.87677108402424, "Cholelithiasis": 8.545022484868394, "Cognitive disorder": 2.27215470601222, "Completed suicide": 3.807880799507685, "Cystitis": 5.055485003510575, "Delirium": 2.1215650104732147, "Dementia Alzheimer's type": 8.361621715817536, "Depersonalisation/derealisation disorder": 13.375895333531496, "Drug eruption": 2.752022883602856, "Drug hypersensitivity": 3.596543828674449, "Drug interaction": 5.336741643674915, "Drug intolerance": 4.258210336661126, "Drug level increased": 2.765427457674132, "Drug reaction with eosinophilia and systemic symptoms": 4.8625093916242506, "Enthesopathy": 19.02226525195053, "Euglycaemic diabetic ketoacidosis": 9.017105327801564, "Feeling jittery": 10.70415470702378, "Femur fracture": 6.088412729507736, "Fibromyalgia": 5.942398000589662, "Fluid retention": 5.198098434574378, "Foot deformity": 3.4266784750706885, "Frequent bowel movements": 3.591085642591316, "Gastric ulcer": 2.087855976471394, "Gastric ulcer haemorrhage": 4.920746983024274, "Gastritis": 4.653093891295279, "Gastrointestinal disorder": 3.429683338716029, "Gastrooesophageal reflux disease": 5.990069125001586, "Glaucoma": 11.661514749400643, "Granuloma": 9.121386530223866, "Hemiplegia": 3.5062420895187807, "Hepatic steatosis": 3.020415781021836, "Hip fracture": 14.259902806493685, "Hypercalcaemia": 4.4704417593419885, "Injury": 5.685786621783332, "Joint range of motion decreased": 2.138890373831185, "Lactic acidosis": 3.737386679172201, "Laryngeal papilloma": 624.8137397924909, "Liver function test abnormal": 2.0804162203060703, "Lymphoedema": 14.568999832387243, "Mast cell activation syndrome": 18.30157064051844, "Metabolic acidosis": 2.4527901017766607, "Metabolic alkalosis": 24.363058398203624, "Migraine": 2.1958011650187097, "Mitral valve incompetence": 2.9873960499119057, "Mood altered": 4.028828927031591, "Musculoskeletal disorder": 2.940669710012466, "Myoclonus": 2.6012558103548904, "Necrotising fasciitis": 11.003400090320032, "Neuropathy peripheral": 2.4833226405458197, "Nitrite urine present": 137.6881342924125, "Oliguria": 3.5625772667323896, "Osteoarthritis": 4.341118862648496, "Osteomyelitis": 10.537403215361934, "Pemphigoid": 2.08149580985475, "Phlebitis": 9.44461549207107, "Psoriasis": 2.4001400884204487, "Psoriatic arthropathy": 2.99949996631996, "Purpura senile": 986.279486566102, "Pyelonephritis acute": 42.67883411725485, "Pyuria": 29.260658892586427, "Quality of life decreased": 3.693080239636271, "Renal artery stenosis": 180.81444083313244, "Renal failure": 2.5725264056595822, "Renal impairment": 2.903683261686369, "Resorption bone increased": 313.39479916085634, "Respiratory papilloma": 1255.7592321339732, "Road traffic accident": 7.658578886873633, "Sciatica": 2.841236451837871, "Septic shock": 2.082406160609268, "Serotonin syndrome": 3.2729065572249314, "Skin lesion": 2.9734036878540904, "Stent placement": 7.906886363784955, "Superficial vein thrombosis": 11.24812065123724, "Suspected suicide": 5.70348602968559, "Syringomyelia": 124.53901351863097, "Tarsal tunnel syndrome": 529.9483074308141, "Thrombophlebitis": 9.611690427339337, "Toxicity to various agents": 3.122081017510918, "Tubulointerstitial nephritis": 4.84254576135494, "Unresponsive to stimuli": 9.023381305198148, "Upper gastrointestinal haemorrhage": 2.532542003870742, "Urinary retention": 3.729241956348934, "Vasculitis": 20.17738209697164, "Vertigo positional": 20.696113086729703, "Vestibular disorder": 43.78855048876494, "Vitamin B12 decreased": 34.9094075788953, "Vitamin D decreased": 8.096134432081547, "White blood cell count decreased": 2.3331872587715963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/251.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/251.json
index 1f00520beb1..57da0da3c1c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/251.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/251.json
@@ -1 +1 @@
-{"Dizziness ": 5.155105603791653, "Parkinson's disease ": 365.8581108859343}
\ No newline at end of file
+{"Acne": 3.007191735212182, "Actinic keratosis": 6.807128655697208, "Acute graft versus host disease": 6.236591736188375, "Acute graft versus host disease in intestine": 4.663064861022632, "Acute pulmonary oedema": 2.8219576041971206, "Acute respiratory distress syndrome": 5.886055921649863, "Adenocarcinoma": 4.040274292800377, "Adenoviral haemorrhagic cystitis": 87.67625859294492, "Adenovirus infection": 9.580502273087346, "Agitation postoperative": 71.6212638934499, "Agranulocytosis": 11.052720005782469, "Amylase increased": 3.8727576143660993, "Anaemia": 2.5223581736838145, "Angiopathy": 2.2840334784553864, "Anogenital warts": 6.1450989340539, "Anti-erythropoietin antibody negative": 12.303962947268866, "Anuria": 2.6687915885424327, "Aphthous ulcer": 2.76770375053504, "Aplasia pure red cell": 12.241267496766191, "Aplastic anaemia": 2.9187250586108844, "Arthritis bacterial": 2.011428569992564, "Ascites": 2.308168225319864, "Aspergillus infection": 10.019641054440182, "Atypical mycobacterial infection": 7.581030826744377, "Autoimmune hepatitis": 2.1963496160591047, "Azotaemia": 3.272608827504853, "B-cell lymphoma": 9.675017260262411, "BK virus infection": 34.80095145944165, "Bacteraemia": 4.6280165082204165, "Bacterial infection": 2.6836830207170173, "Bacterial sepsis": 6.078696249457242, "Basal cell carcinoma": 9.771372352304793, "Bicytopenia": 8.352083319475836, "Blood creatinine abnormal": 2.5585802054718263, "Blood creatinine increased": 4.736436304296665, "Blood disorder": 2.657640193760594, "Blood immunoglobulin G decreased": 7.935563833532542, "Blood iron decreased": 4.28839614809251, "Bone marrow failure": 5.511771945516707, "Bowen's disease": 39.79088570548631, "Brain abscess": 9.942159098670112, "Brain herniation": 5.01506800087939, "Bronchial carcinoma": 19.83693831669584, "Bronchial disorder": 6.201636909363803, "Bronchiectasis": 5.69280051752787, "Bronchiolitis": 3.074548275256527, "Bronchopulmonary aspergillosis": 12.864963862675692, "Burkitt's lymphoma": 38.84832194107833, "COVID-19 pneumonia": 5.812902923802018, "Cardiac hypertrophy": 6.826024908579745, "Cardiac tamponade": 2.3023217465307817, "Cardiopulmonary failure": 2.2870583019735395, "Cell death": 3.764532078750252, "Central nervous system lymphoma": 30.663042713454995, "Central nervous system vasculitis": 8.671620104057371, "Cerebral ischaemia": 2.915421259496537, "Cerebral toxoplasmosis": 10.286118901756373, "Cervix carcinoma": 4.425053955395272, "Cholangitis": 4.212306657472845, "Cholecystitis chronic": 6.373639098723926, "Cholestasis": 2.833708272340033, "Chronic allograft nephropathy": 38.37864990922531, "Colitis": 3.3723189703242804, "Colon cancer": 2.532822812065124, "Coma": 3.470860190543678, "Complications of transplanted kidney": 27.63145745664613, "Congenital aplasia": 4.804523611887899, "Congestive hepatopathy": 6.504272280025555, "Cryptococcosis": 16.15380623465438, "Cushingoid": 4.763727828644067, "Cystitis haemorrhagic": 8.64488505707026, "Cystitis 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2.9013569700321047, "Gastrooesophageal reflux disease": 3.652468374818812, "Gingival hypertrophy": 5.931761485528994, "Glomerulonephritis": 3.091229221506835, "Glomerulonephritis membranoproliferative": 14.033426820952116, "Glomerulonephritis membranous": 6.078360609471277, "Graft versus host disease": 7.402579540290782, "Graft versus host disease in gastrointestinal tract": 4.47633719783671, "Graft versus host disease in lung": 16.701262780160683, "Graft versus host disease in skin": 3.4346999175371637, "Granulocytopenia": 3.443859176813701, "Groin infection": 23.87627696721794, "H1N1 influenza": 10.88361965789094, "Haemodialysis": 5.138892724575992, "Haemodynamic instability": 2.081443448132596, "Haemoglobin abnormal": 2.375240766021732, "Haemoglobin increased": 2.1910356028419717, "Haemolysis": 3.054183651322782, "Haemolytic anaemia": 3.067169650168879, "Haemolytic uraemic syndrome": 11.000863947247426, "Haemophagocytic lymphohistiocytosis": 6.764452102797425, "Haemorrhoidal 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"Pneumonia cytomegaloviral": 22.247557188205835, "Pneumonia fungal": 7.2647681602303535, "Pneumonia klebsiella": 6.13989666463586, "Pneumonia legionella": 7.915553703535701, "Pneumonia pneumococcal": 11.64158435404511, "Pneumonia pseudomonal": 6.1560648912048, "Pneumonia viral": 3.566068220181602, "Polyomavirus-associated nephropathy": 204.5677559711944, "Post transplant lymphoproliferative disorder": 74.08818644654824, "Posterior reversible encephalopathy syndrome": 7.766150526497181, "Postoperative wound infection": 3.960664057259996, "Progressive multifocal leukoencephalopathy": 32.27556492183811, "Protein urine present": 2.702731626954584, "Proteinuria": 4.0212275551435015, "Pseudomembranous colitis": 4.955971336538646, "Pseudomonal sepsis": 4.076770399202561, "Pseudomonas infection": 4.105616766138381, "Pulmonary alveolar haemorrhage": 3.917607016456537, "Pulmonary fibrosis": 3.00605712829682, "Pulmonary tuberculosis": 11.189429596879986, "Pyelonephritis": 9.586933559499982, "Pyelonephritis acute": 9.86140304445184, "Pyoderma": 19.305992922623037, "Pyuria": 9.141311021764157, "Rales": 3.077323551518436, "Red blood cell sedimentation rate abnormal": 3.021997516263152, "Renal artery stenosis": 10.267382864777602, "Renal impairment": 3.4204124702231096, "Renal transplant failure": 29.00662466095116, "Renal tubular atrophy": 12.50718494812206, "Renal tubular disorder": 5.984436146997695, "Renal tubular necrosis": 4.137641942556373, "Respiratory failure": 2.4723221337522747, "Respiratory tract congestion": 3.059440141374164, "Respiratory tract infection": 2.0306064037897342, "Scleroderma": 4.633418496939563, "Sepsis": 4.368238754798314, "Septic shock": 4.4630454740893, "Serum sickness": 5.153811846285623, "Skin cancer": 8.482130068151777, "Skin papilloma": 4.691276916849734, "Skin ulcer": 2.1307059355369518, "Sleep disorder due to general medical condition, insomnia type": 8.207025815350317, "Small intestinal obstruction": 3.894511014543463, "Squamous cell 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6.202962028833478, "Urinary tract infection viral": 75.60446572818122, "Urine output decreased": 2.955895877724041, "Urosepsis": 4.78818443774698, "Uterine cancer": 3.159900391833776, "Varicella": 3.253127776648729, "Varicella zoster pneumonia": 37.97330019099558, "Varicella zoster virus infection": 5.429395185800526, "Venoocclusive liver disease": 2.833404066768685, "Viral haemorrhagic cystitis": 26.348549596757515, "Viral infection": 4.28558073880074, "Vulval disorder": 16.47010575486855, "White blood cell count decreased": 2.271689447587701, "Wound dehiscence": 6.644874182438467}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/252.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/252.json
index de7efa5c516..2f96193ae8a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/252.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/252.json
@@ -1 +1 @@
-{"Malignant neoplasm progression ": 14.594242325161998}
\ No newline at end of file
+{"Abdominal distension": 2.213128316038894, "Aggression": 3.2454797414966223, "Alanine aminotransferase increased": 5.06821736970525, "Aspartate aminotransferase increased": 4.224863391685897, "Balance disorder": 2.378210072975129, "Blood HIV RNA increased": 84.61754071722183, "Blood creatine phosphokinase increased": 6.3268085511644445, "Blood creatinine increased": 2.358429670540305, "Condition aggravated": 2.139694542240019, "Depression": 2.146823113076952, "Drug interaction": 2.8602262928930893, "Drug resistance": 10.89045383743329, "Dysphagia": 2.249869611395156, "Enanthema": 133.48611436397306, "Gamma-glutamyltransferase increased": 5.677064344594642, "Glaucoma": 18.365198130685133, "Hepatic cytolysis": 6.362524548674013, "Hepatic enzyme increased": 3.340333528945695, "Hepatitis B reactivation": 37.90994644162344, "Immune reconstitution inflammatory syndrome": 39.17421059660683, "Ischaemic stroke": 13.789760203676, "Jaundice": 5.3434896740701445, "Lipids increased": 97.2135798576956, "Live birth": 17.892309315246393, "Malaria": 314.199920891648, "Muscle twitching": 5.826827876328659, "Nervous system disorder": 15.924331632167846, "Oedema": 2.5430580199616366, "Oedema peripheral": 2.027019999878517, "Pancytopenia": 2.8369679267689256, "Pathogen resistance": 34.94696541122213, "Petit mal epilepsy": 38.55345919083141, "Prinzmetal angina": 147.42765613363318, "Rash maculo-papular": 5.948979686090576, "Renal impairment": 3.5996340161768408, "Renal tubular necrosis": 24.838953255165272, "Treatment noncompliance": 16.09923868125667, "Viral mutation identified": 91.43272044930563, "Virologic failure": 42.95093565629815, "Vitreous haemorrhage": 76.49031122004548}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/253.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/253.json
index 8500c77ca15..f9010747687 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/253.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/253.json
@@ -1 +1 @@
-{"Bradycardia ": 132.991069893136, "Hypotension ": 49.04692137701578, "Overdose ": 79.27662993296236, "Unresponsive to stimuli ": 466.9616320756938}
\ No newline at end of file
+{"Coma scale abnormal": 449.80007570716, "Drug interaction": 13.07460950115554}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/254.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/254.json
index 96919982894..ab5cd98869c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/254.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/254.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.05684111721901, "Adjustment disorder with depressed mood ": 47.68692017314798, "Adverse event ": 9.47630056657221, "Bone erosion ": 55.72122966408984, "Breast cancer stage III ": 43.569845236308325, "Bursitis ": 15.908669035902443, "C-reactive protein abnormal ": 28.349040487497543, "C-reactive protein increased ": 15.29486526640891, "Contraindicated product administered ": 5.625805171944957, "Crohn's disease ": 17.213120896340417, "Drug hypersensitivity ": 4.546215026516102, "Dry mouth ": 4.220716192050152, "Exostosis ": 61.60156459260583, "Folliculitis ": 15.334742669003152, "Gait disturbance ": 3.986380168896669, "Glossodynia ": 7.101370809522758, "Hand deformity ": 11.065622066544838, "Hepatic cirrhosis ": 18.610653760146523, "Hypercholesterolaemia ": 29.157764496522365, "Illness ": 3.137524462066356, "Impaired healing ": 11.919250675325646, "Infection ": 4.241586066944304, "Intentional product misuse ": 9.408359506921531, "Joint stiffness ": 16.358608296790425, "Laryngitis ": 57.180123344778046, "Live birth ": 35.00823367625806, "Liver injury ": 10.907271545275607, "Loss of personal independence in daily activities ": 6.8156675913041225, "Musculoskeletal stiffness ": 4.0847468496939445, "Red blood cell sedimentation rate abnormal ": 73.63894661296554, "Rheumatoid arthritis ": 9.303008597753555, "Synovitis ": 16.266676474083628, "Therapeutic product effect decreased ": 9.091449399098853, "Therapeutic product effect incomplete ": 5.90620767203617, "Treatment failure ": 4.859685694399646}
\ No newline at end of file
+{"Foetal exposure during pregnancy": 39.82482979404303, "Foetal growth restriction": 396.3152677772589}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/255.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/255.json
index 3b56b981cbc..86c6acf1279 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/255.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/255.json
@@ -1 +1 @@
-{"Adverse event ": 7.263108871264496, "Injection site swelling ": 2.458172360727372, "Interchange of vaccine products ": 5.423395614628828, "Neck pain ": 3.2345181669802874, "Pallor ": 6.8690288750390645, "Presyncope ": 5.612881996941176, "Syncope ": 4.246273962058561}
\ No newline at end of file
+{"Dizziness": 5.155069816960532, "Parkinson's disease": 365.8581108859343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/256.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/256.json
index 8d5226263ee..9198d2692fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/256.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/256.json
@@ -1 +1 @@
-{"Blood oestrogen increased ": 3972.331408983344, "Condition aggravated ": 11.616088748189116, "Drug interaction ": 12.14436328125141, "Drug level decreased ": 328.1129832369037, "Generalised tonic-clonic seizure ": 56.12817963761371, "Ovarian hyperstimulation syndrome ": 1249.972431842877}
\ No newline at end of file
+{"Malignant neoplasm progression": 14.594242325161998}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/257.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/257.json
index f36a520c8f9..4802d3bfeff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/257.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/257.json
@@ -1 +1 @@
-{"Abdominal distension ": 18.80638548583657, "Abdominal pain ": 4.80910070417856, "Abortion spontaneous ": 41.36617298931657, "Ascites ": 89.61599178002868, "Constipation ": 4.236723728102946, "Haemoperitoneum ": 166.83489865666, "Ovarian hyperstimulation syndrome ": 1863.3713266267764, "Pelvic fluid collection ": 654.9371394831838, "Pleural effusion ": 5.7916252601346}
\ No newline at end of file
+{"Bradycardia": 132.9869017825693, "Hypotension": 49.04578753815733, "Overdose": 79.27662993296236, "Unresponsive to stimuli": 466.9102487072499}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/258.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/258.json
index bb042e22fa0..fcf914e2109 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/258.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/258.json
@@ -1 +1 @@
-{"Anaemia ": 2.460183758669652, "Conjunctivitis ": 8.907819543092893, "Dermatitis ": 7.4469670360214515, "Dermatitis acneiform ": 121.15455861306222, "Diarrhoea ": 3.0604621943528665, "Disease progression ": 6.034844951795019, "Febrile neutropenia ": 7.222634621859203, "Folliculitis ": 7.631578051542689, "Haematotoxicity ": 22.83093732451928, "Hypomagnesaemia ": 20.937169901068646, "Hypotension ": 2.185794251451413, "Interstitial lung disease ": 5.76264336238349, "Leukopenia ": 5.308338791846951, "Malignant neoplasm progression ": 7.610465091458724, "Mucosal inflammation ": 12.816613870387014, "Myelosuppression ": 13.933715967767142, "Neuropathy peripheral ": 8.314807185893896, "Neurotoxicity ": 8.372217811797878, "Neutropenia ": 11.068452419675143, "Neutrophil count decreased ": 6.661346274489232, "Palmar-plantar erythrodysaesthesia syndrome ": 3.2096717802750594, "Paronychia ": 34.87132313773825, "Polyneuropathy ": 11.867715054267329, "Rash ": 2.977135524719828, "Respiratory failure ": 3.644110403263234, "Sepsis ": 3.39270863404804, "Skin fissures ": 25.5101441558486, "Skin lesion ": 4.72614953093795, "Skin toxicity ": 139.9538247996285, "Stomatitis ": 8.258065864036862, "Thrombocytopenia ": 3.968192647992335, "White blood cell count decreased ": 4.273753045488423}
\ No newline at end of file
+{"Abdominal discomfort": 2.05684111721901, "Adjustment disorder with depressed mood": 47.68692017314798, "Adverse event": 9.47630056657221, "Bone erosion": 55.72122966408984, "Breast cancer stage III": 43.569845236308325, "Bursitis": 15.908669035902443, "C-reactive protein abnormal": 28.349040487497543, "C-reactive protein increased": 15.29486526640891, "Contraindicated product administered": 5.625805171944957, "Crohn's disease": 17.213120896340417, "Drug hypersensitivity": 4.546215026516102, "Dry mouth": 4.220716192050152, "Exostosis": 61.60156459260583, "Folliculitis": 15.334742669003152, "Gait disturbance": 3.9863079022058026, "Glossodynia": 7.101370809522758, "Hand deformity": 11.065622066544838, "Hepatic cirrhosis": 18.610653760146523, "Hypercholesterolaemia": 29.157764496522365, "Illness": 3.137524462066356, "Impaired healing": 11.919250675325646, "Infection": 4.241586066944304, "Intentional product misuse": 9.408359506921531, "Joint stiffness": 16.358608296790425, "Laryngitis": 57.180123344778046, "Live birth": 35.00823367625806, "Liver injury": 10.907271545275607, "Loss of personal independence in daily activities": 6.8156675913041225, "Musculoskeletal stiffness": 4.0847468496939445, "Red blood cell sedimentation rate abnormal": 73.63894661296554, "Rheumatoid arthritis": 9.303008597753555, "Synovitis": 16.266676474083628, "Therapeutic product effect decreased": 9.091449399098853, "Therapeutic product effect incomplete": 5.90620767203617, "Treatment failure": 4.859685694399646}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/259.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/259.json
index 2843bb2e4d8..9fa7902c16f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/259.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/259.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.825945050029496, "Abnormal behaviour ": 12.905389238812257, "Abnormal dreams ": 57.498055495201605, "Abnormal sleep-related event ": 8.849465175938487, "Accommodation disorder ": 2.200870636577734, "Acute myocardial infarction ": 2.836886430456195, "Acute psychosis ": 8.98584171860406, "Adjustment disorder ": 2.0974310618034138, "Adjustment disorder with depressed mood ": 2.168077461303479, "Affect lability ": 6.418778886144247, "Affective disorder ": 9.813886018239751, "Aggression ": 20.10842703355831, "Agitated depression ": 28.458013389646744, "Agitation ": 7.189002809768852, "Agoraphobia ": 13.309913500993988, "Alcohol abuse ": 3.6238319326479775, "Alcohol interaction ": 28.7329509594068, "Alcohol intolerance ": 13.012596496332264, "Alcohol poisoning ": 6.930295939797584, "Alcohol use ": 10.90144804920299, "Alcoholism ": 6.64324411259996, "Amnesia ": 4.975530921435935, "Anger ": 24.215432472450004, "Angina pectoris ": 2.283953208187737, "Anxiety ": 4.780971487727802, "Anxiety disorder ": 4.780703734414313, "Apathy ": 6.476834998407813, "Behaviour disorder ": 3.3111966839362625, "Bipolar I disorder ": 6.982177102643804, "Bipolar disorder ": 8.401940997089007, "Blindness transient ": 2.712778228002888, "Blood alcohol increased ": 6.960079101487062, "Bradyphrenia ": 2.8100834984163345, "Brief psychotic disorder with marked stressors ": 36.41218226056184, "Burnout syndrome ": 13.019035498520289, "Claustrophobia ": 7.383475853073325, "Completed suicide ": 3.953088212387927, "Constipation ": 2.161841898570996, "Conversion disorder ": 5.196758584192865, "Coordination abnormal ": 3.986987174558451, "Crying ": 9.627748564363769, "Daydreaming ": 6.5248955498155246, "Decreased interest ": 10.753986066006012, "Delusion ": 5.598183751278615, "Dependence ": 2.776768499441, "Depersonalisation/derealisation disorder ": 6.006566643859938, "Depressed mood ": 30.89667921573522, "Depression ": 17.582043903074794, "Depression suicidal ": 20.72917340619236, "Depressive symptom ": 19.49443370841311, "Derealisation ": 11.78000862654678, "Disease recurrence ": 2.178351501359972, "Disinhibition ": 2.3321110003189918, "Disorientation ": 2.887547616825142, "Dissociation ": 10.39283276986558, "Dissociative disorder ": 5.028818683504162, "Disturbance in attention ": 4.1690783089417485, "Dysgeusia ": 2.2661788981383824, "Dyspepsia ": 2.070130293549555, "Dysphemia ": 3.146561454865356, "Emotional disorder ": 11.24919960107046, "Emotional poverty ": 9.420701779334095, "Emphysema ": 3.239620643938389, "Epilepsy ": 2.1944611036790267, "Euphoric mood ": 5.370952117558132, "Fear ": 6.443653022191827, "Fear of death ": 2.224498456685196, "Feeling abnormal ": 4.620922660865727, "Feeling drunk ": 3.878582112330203, "Feeling guilty ": 7.449904340325764, "Feeling of despair ": 10.6610848793209, "Feeling of relaxation ": 11.54939764678119, "Feelings of worthlessness ": 8.168554746748166, "Flashback ": 12.205967416860345, "Flat affect ": 14.006863644612585, "Flatulence ": 4.416416622252958, "Food aversion ": 3.040702214607864, "Frustration tolerance decreased ": 4.082880585803816, "Gastric mucosal lesion ": 7.06368826931453, "Gingival pain ": 3.854249837068328, "Gingivitis ": 2.3578315615691428, "Glossitis ": 2.463127733345117, "Haematochezia ": 2.172045734848657, "Hallucination ": 5.764329417508332, "Hallucination, auditory ": 6.408686197751896, "Hallucination, visual ": 3.9217213864839504, "Hallucinations, mixed ": 5.490112050956109, "Hangover ": 3.3336090215114127, "Homicidal ideation ": 21.39171824046908, "Hostility ": 9.939555826403968, "Hunger ": 2.0013112574652423, "Hyperphagia ": 3.619060167909501, "Hypersomnia ": 2.329649766128405, "Hyperventilation ": 2.2273284450188022, "Hypomania ": 5.579466313599434, "Ileus ": 2.1735371155199514, "Illusion ": 3.2991472309901693, "Impaired driving ability ": 9.715193054552389, "Impatience ": 10.22638179235868, "Impulsive behaviour ": 7.822267655108584, "Inappropriate affect ": 3.18032499056214, "Increased appetite ": 5.760277069053683, "Indifference ": 8.391871354704096, "Infarction ": 3.2579505493089065, "Insomnia ": 5.450849072498638, "Intentional self-injury ": 3.650554367449632, "Irritability ": 10.080761153280072, "Judgement impaired ": 4.025293448344396, "Labyrinthitis ": 3.0727936042571256, "Libido decreased ": 3.200033211705383, "Libido disorder ": 4.353121827090177, "Libido increased ": 5.563645123697841, "Listless ": 2.2563440532310266, "Logorrhoea ": 3.700125593768914, "Loss of consciousness ": 2.0993366797746926, "Loss of control of legs ": 2.421090709512496, "Loss of employment ": 2.603477485978756, "Loss of libido ": 2.4345156562230468, "Major depression ": 8.878504872299018, "Mania ": 7.747715824987102, "Memory impairment ": 2.9491196392023493, "Mental disorder ": 7.2335849714411795, "Mental impairment ": 3.59661557933796, "Mood altered ": 24.553460101514187, "Mood swings ": 20.842103167413807, "Morbid thoughts ": 25.744439973842464, "Mouth swelling ": 2.3675601942732225, "Mouth ulceration ": 2.5022053444566943, "Musculoskeletal chest pain ": 2.6063396790172555, "Myopia ": 4.623903842525274, "Narcolepsy ": 4.251340436413179, "Nausea ": 2.3260723104196552, "Negative thoughts ": 34.82197659870145, "Nervousness ": 5.365025643749227, "Neurosis ": 4.857320177532466, "Nicotine dependence ": 2.912122964207541, "Nightmare ": 20.71423323981967, "Nocturia ": 3.3100712653689586, "Obsessive thoughts ": 14.796793945329526, "Obsessive-compulsive disorder ": 2.287928930852209, "Panic attack ": 10.056562003766496, "Panic disorder ": 9.376908754594163, "Panic reaction ": 10.437362256158758, "Paranoia ": 25.11822714408249, "Persecutory delusion ": 4.484071041794281, "Personality change ": 20.01295082233087, "Personality disorder ": 7.266990683499798, "Petit mal epilepsy ": 2.298467437469513, "Pharyngeal swelling ": 2.0559874966711877, "Physical assault ": 23.912197265454942, "Physical deconditioning ": 2.844249294995618, "Pollakiuria ": 2.09095290487465, "Polydipsia ": 2.6919628398941797, "Polyuria ": 2.662425226860789, "Poor quality sleep ": 4.330357210879198, "Pre-existing condition improved ": 10.136151290194698, "Prescription drug used without a prescription ": 5.228148959205406, "Product availability issue ": 5.336997095177058, "Product impurity ": 26.225322480846494, "Product supply issue ": 2.5991970940644884, "Psychiatric decompensation ": 5.554664792548061, "Psychiatric symptom ": 10.780484138968731, "Psychomotor hyperactivity ": 2.0408074117008197, "Psychotic behaviour ": 9.268239703141166, "Psychotic disorder ": 13.42769021943612, "Recalled product administered ": 9.627420371106616, "Restlessness ": 3.5073719734347177, "Retching ": 2.1300898234943406, "Reversible cerebral vasoconstriction syndrome ": 4.025814187258132, "Road traffic accident ": 6.422506228763827, "Schizophrenia ": 4.4376329733018025, "Schizophreniform disorder ": 10.27620016105712, "Self esteem decreased ": 7.014420232136416, "Self-destructive behaviour ": 4.324109170815182, "Self-injurious ideation ": 34.66549004350117, "Sleep disorder ": 5.167342683377534, "Sleep talking ": 4.565114610802602, "Sleep terror ": 3.455257523423543, "Snoring ": 2.2131542156405373, "Social avoidant behaviour ": 14.43004080484692, "Somnambulism ": 9.140703014946228, "Stress ": 3.944521303528497, "Suicidal behaviour ": 25.495078637256118, "Suicidal ideation ": 27.712921871308144, "Suicide attempt ": 6.454842003398301, "Suspiciousness ": 10.175205060162927, "Tachyphrenia ": 6.760559695497684, "Taste disorder ": 2.820162667201814, "Tearfulness ": 42.72366678673967, "Tension ": 2.9726039916013787, "Therapeutic response unexpected ": 2.291988596302023, "Thinking abnormal ": 18.17537076495831, "Thirst ": 2.370156846381854, "Tobacco user ": 122.80309758044258, "Tobacco withdrawal symptoms ": 373.64173975128256, "Tongue coated ": 3.4152138190619423, "Tongue dry ": 3.245085857609662, "Tongue erythema ": 2.6545457502267094, "Tunnel vision ": 4.359874933571327, "Urine output increased ": 2.427848163239457, "Verbal abuse ": 20.19304384989637, "Vestibular disorder ": 2.1797978962936613, "Violence-related symptom ": 54.3131394415617, "Weaning failure ": 23.47599802790567, "Withdrawal syndrome ": 4.110460527981488}
\ No newline at end of file
+{"Adverse event": 7.263108871264496, "Injection site swelling": 2.458172360727372, "Interchange of vaccine products": 5.4231511804199375, "Neck pain": 3.2345181669802874, "Pallor": 6.86859452243747, "Presyncope": 5.612881996941176, "Syncope": 4.246215515485214}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/26.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/26.json
index 06deaef6d37..7c8cee3dc13 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/26.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/26.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 90.6629433602092, "Anaemia ": 2.023261524132719, "Colitis ": 7.604807005373669, "Constipation ": 3.403794099978616, "Disease progression ": 3.0142230171170707, "Enterocolitis ": 23.40533475392848, "Febrile neutropenia ": 49.705165153382254, "Hodgkin's disease ": 304.809430858085, "Hodgkin's disease recurrent ": 382.1259086586443, "Intentional product use issue ": 3.185199069056277, "Interstitial lung disease ": 3.065816015355953, "Leukopenia ": 2.265747274505872, "Malignant neoplasm progression ": 2.500141335478064, "Myelosuppression ": 5.235131906938769, "Myositis ": 32.32992431704492, "Neoplasm progression ": 4.999396475545985, "Neuropathy peripheral ": 59.33875744788615, "Neutropenia ": 16.77784833495564, "Neutrophil count decreased ": 29.41691229191931, "Off label use ": 3.739881920948621, "Pancytopenia ": 3.3333090118730357, "Peripheral sensory neuropathy ": 28.956403504266547, "Pneumocystis jirovecii pneumonia ": 36.70440870977886, "Pneumonia ": 2.0239026324312097, "Pneumonitis ": 6.90516272421026, "Polyneuropathy ": 8.777759897138928, "Second primary malignancy ": 35.24043607138998, "Sepsis ": 5.31194250743399, "Vascular pain ": 40.88787656818098, "White blood cell count decreased ": 5.397435728311549}
\ No newline at end of file
+{"Abdominal discomfort": 10.639100003465748, "Abdominal distension": 3.045973043307656, "Abdominal pain upper": 3.411168311233947, "Adjustment disorder with depressed mood": 48.80978239367883, "Adrenal insufficiency": 3.64605433114416, "Adverse drug reaction": 7.106945460347239, "Adverse event": 4.2306841929488135, "Adverse reaction": 20.489805998400367, "Alanine aminotransferase abnormal": 9.996310073338542, "Allergy to chemicals": 5.555172140707873, "Alopecia": 9.903465517031082, "Amaurosis fugax": 11.048033027349184, "Amnesia": 4.040294810551348, "Ankle arthroplasty": 86.29767563539538, "Anti-cyclic citrullinated peptide antibody": 115.09583495639583, "Anti-cyclic citrullinated peptide antibody positive": 50.12985312542799, "Antibody test positive": 12.928797803749005, "Anticipatory anxiety": 18.69818385239382, "Antinuclear antibody positive": 3.3895704949607395, "Arthritis": 4.965949794510359, "Arthropathy": 22.016279658851648, "Autoimmune disorder": 19.820134085846625, "Back disorder": 11.189595500143756, "Back injury": 20.97463279111221, "Basal cell carcinoma": 6.9183269156419005, "Blepharospasm": 31.394954171514797, "Blister": 10.413714540464053, "Blood cholesterol": 13.54536066986797, "Blood cholesterol increased": 20.70148800325906, "Blood iron abnormal": 2.479381639879818, "Blood parathyroid hormone decreased": 29.74465274868898, "Body height below normal": 44.04109338159553, "Bone density increased": 22.67581898634662, "Bone erosion": 19.76485774598445, "Breast cancer stage II": 125.3588928616272, "Breast cancer stage III": 98.71375960253198, "Bronchiectasis": 7.462688861583084, "Burns second degree": 23.40416026595542, "Bursitis": 30.928027513727223, "C-reactive protein": 107.4405854327988, "C-reactive protein abnormal": 48.15253189257161, "C-reactive protein increased": 12.52562041887948, "Cardiac murmur": 2.9318401478246763, "Catarrh": 10.96363861421304, "Chronic sinusitis": 21.033229474782072, "Coeliac disease": 21.00422222880301, "Colitis": 3.715159153588868, "Colitis ulcerative": 7.306519945897834, "Condition aggravated": 4.790400508088602, "Confusional state": 4.10380741676198, "Congenital anomaly": 2.062904774984414, "Contraindicated product administered": 18.2342716860626, "Contraindication to vaccination": 4.413621792166813, "Contusion": 4.250706128528308, "Crepitations": 2.537896496830896, "Crohn's disease": 4.658656223028392, "Cushingoid": 3.217221915307109, "Dactylitis": 2.575086086936821, "Death neonatal": 2.155852894417445, "Deep vein thrombosis postoperative": 100.98854467858018, "Deformity": 7.511837772100804, "Delirium": 3.8278406820717272, "Depression": 2.139180965105183, "Disability": 11.014695245370092, "Discomfort": 12.412684092523174, "Dislocation of vertebra": 66.04760176205484, "Disseminated tuberculosis": 2.220028485748865, "Drug hypersensitivity": 6.774722957229571, "Drug ineffective": 2.3198660401570628, "Drug intolerance": 10.019030552929555, "Drug specific antibody": 8.838268975352372, "Drug specific antibody present": 11.131916247995571, "Drug tolerance": 24.90428416953105, "Drug tolerance decreased": 25.176768577985555, "Drug-induced liver injury": 4.090777511275945, "Dry mouth": 3.870903133406901, "Duodenal ulcer perforation": 45.01826715109623, "Dyspepsia": 5.6284455796841, "Ear infection": 4.5865456916610485, "Ear injury": 15.368448343880647, "Enthesopathy": 24.62397824919833, "Exostosis": 10.68683980553677, "Exposure during pregnancy": 4.545346793071274, "Eye injury": 24.46119448188546, "Facet joint syndrome": 88.47757471784507, "Faecal calprotectin increased": 6.360422721300931, "Fear of injection": 8.084947605440783, "Female genital tract fistula": 23.686914805053664, "Fibromyalgia": 19.820423658705856, "Finger deformity": 24.87640129551497, "Folliculitis": 26.28013517982577, "Foot deformity": 11.478885576691944, "Foot operation": 8.577991729237564, "Fracture delayed union": 22.765765025494105, "Frequent bowel movements": 12.153078338121496, "Gait inability": 4.023288057629049, "Gastroenteritis viral": 5.794677887163791, "Gastrointestinal bacterial overgrowth": 3.501374511052364, "Gastrointestinal disorder": 4.450068141186018, "General physical health deterioration": 6.285846972803346, "Gingival pain": 4.395535279019419, "Glossodynia": 25.24085094901, "Granuloma": 3.10679708404994, "Granuloma skin": 26.57819832385996, "Grip strength": 15.109736357403614, "Grip strength decreased": 19.084379926190056, "Groin abscess": 2.570027423952936, "Haematochezia": 3.3900736521831387, "Hand deformity": 32.18412249307124, "Helicobacter infection": 32.68439532955782, "Hepatic cirrhosis": 2.6124044440159806, "Hepatic enzyme increased": 5.58946194037622, "Hepatitis": 2.3651738430337663, "Hepatosplenic T-cell lymphoma": 6.724283580964504, "Hidradenitis": 8.4523436505689, "Hip arthroplasty": 6.034546633512429, "Human anti-human antibody test": 35.954274527187025, "Human antichimeric antibody positive": 68.82953584016988, "Hyperadrenocorticism": 13.862187762210567, "Hypercalcaemia": 3.883396605955818, "Hypercholesterolaemia": 8.361652525353406, "Hypersensitivity": 2.73481565836246, "Hypocalcaemia": 3.4448457518504365, "Hypopnoea": 5.766419070385762, "Ileal stenosis": 4.054204185582731, "Ill-defined disorder": 9.970788545583048, "Immunodeficiency": 4.971955896145842, "Impaired healing": 12.112984835410993, "Impaired quality of life": 8.911137040425606, "Impaired work ability": 2.082007377954231, "Infection": 3.650476051184509, "Inflammation": 6.237708263367304, "Infusion related reaction": 17.138224799338758, "Infusion site reaction": 7.183673498558482, "Injury": 10.369708105875926, "Intentional product use issue": 7.699157809595462, "Investigation abnormal": 2.370025373911349, "Iodine allergy": 3.7628030309844966, "Irritable bowel syndrome": 10.958303698148963, "Joint ankylosis": 6.169604752142789, "Joint destruction": 66.29193317804193, "Joint dislocation": 5.662995566305843, "Joint effusion": 2.6817215856208683, "Joint laxity": 4.350710000482538, "Joint range of motion decreased": 12.644201120682736, "Joint stiffness": 3.236248552680786, "Joint swelling": 5.042387765396186, "Juvenile idiopathic arthritis": 7.353894197048209, "Knee arthroplasty": 5.035535320651137, "Laryngitis": 5.005343703164744, "Limb deformity": 4.802337983500555, "Lip dry": 9.19310088852793, "Live birth": 6.873898683032275, "Liver function test increased": 3.208579480077498, "Liver injury": 8.729820800967543, "Loose body in joint": 47.79062556477066, "Loss of personal independence in daily activities": 2.210579080891328, "Loss of therapeutic response": 2.5010504652036154, "Lower limb fracture": 2.3123451828357, "Lower respiratory tract infection": 2.670590427251921, "Lupus vulgaris": 128.46915977709304, "Lupus-like syndrome": 6.555551656607691, "Macular degeneration": 19.968191539330903, "Maternal exposure during pregnancy": 6.089418813686689, "Maternal exposure timing unspecified": 3.9712551802630474, "Mean cell haemoglobin decreased": 6.810228408093049, "Mean cell volume decreased": 5.876452180461031, "Mean platelet volume decreased": 8.927588469904183, "Medication error": 2.1332638559199517, "Mobility decreased": 4.761755349003113, "Muscle injury": 8.775799809338043, "Musculoskeletal deformity": 27.880025492883345, "Musculoskeletal disorder": 3.238516872931208, "Musculoskeletal pain": 3.1773361366869346, "Musculoskeletal stiffness": 2.7489974486060222, "Nail disorder": 2.0286829127982475, "Non-alcoholic fatty liver": 4.279958996178615, "Noninfective gingivitis": 2.451852486064743, "Obesity": 7.523767792424784, "Onychomadesis": 35.375835258551376, "Onychomycosis": 32.21729653862994, "Oral candidiasis": 7.326575543361769, "Oral discomfort": 2.7393842836719133, "Osteoarthritis": 3.172191646082732, "Osteoporotic fracture": 3.53101621530496, "Panniculitis": 8.630576811801054, "Paraesthesia oral": 4.871001672239942, "Parathyroid disorder": 11.7300276302105, "Parathyroidectomy": 5.252170055826456, "Pemphigus": 24.43029102165081, "Pericarditis": 5.686404094315347, "Peripheral venous disease": 22.15785426446209, "Pityriasis rubra pilaris": 4.959180047079559, "Plasmablastic lymphoma": 4.401711987377291, "Polyarthritis": 5.724400375663205, "Porphyria acute": 5.591546909025744, "Pregnancy": 2.086282777303257, "Prescribed overdose": 2.649154763026727, "Prescribed underdose": 5.617573005234, "Procedural pain": 20.613889272672285, "Proctitis": 20.476742087331782, "Product label confusion": 3.917469629525319, "Product temperature excursion issue": 12.39719897979549, "Product use issue": 5.208208537002689, "Psoriatic arthropathy": 15.646335526989224, "Pulmonary fibrosis": 5.0953028542528, "Pustular psoriasis": 2.514800850119804, "Pyoderma gangrenosum": 2.840154798548823, "Radiculopathy": 16.814992095198797, "Rectal haemorrhage": 3.683858190920003, "Red blood cell sedimentation rate": 14.774755516347254, "Red blood cell sedimentation rate abnormal": 13.83176222551922, "Red blood cell sedimentation rate 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3.152119328421383, "Therapeutic product effect decreased": 5.862857282642785, "Therapeutic product effect incomplete": 3.4473623278116103, "Therapy non-responder": 2.517343296395937, "Treatment failure": 5.551396039402764, "Type 2 diabetes mellitus": 4.104228939743751, "Ulcer haemorrhage": 4.077639802397177, "Urinary tract disorder": 3.202506374159399, "Vaginal discharge": 11.706274721017598, "Vaginal flatulence": 26.045754531911037, "Vulval disorder": 2.6975095142422063, "Whipple's disease": 9.216198671557253, "Wound": 13.088414340167366, "Wound complication": 2.270414829792151, "Wound infection": 10.921455017242142, "X-ray abnormal": 9.016356930992076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/260.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/260.json
index 5bae2ccdced..dbb2377a786 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/260.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/260.json
@@ -1 +1 @@
-{"Alopecia ": 3.398085329742896, "Gait disturbance ": 3.641648044473112, "Neoplasm malignant ": 10.777709124109515, "Pneumonia ": 2.0334723752446258}
\ No newline at end of file
+{"Blood oestrogen increased": 3972.331408983344, "Condition aggravated": 11.616088748189116, "Drug interaction": 12.14436328125141, "Drug level decreased": 328.1129832369037, "Generalised tonic-clonic seizure": 56.12817963761371, "Ovarian hyperstimulation syndrome": 1249.972431842877}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/261.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/261.json
index 088d4ee292c..9167ab093e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/261.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/261.json
@@ -1 +1 @@
-{"Anaphylactic reaction ": 3.693053332732827, "Anaphylactic shock ": 2.5377056795273143, "Apallic syndrome ": 25.90289805646156, "Arthralgia ": 2.1918877661036844, "Blister ": 23.25443792693571, "Confusional state ": 7.016580965850869, "Contraindicated product administered ": 12.315800279230569, "Contusion ": 6.856317590891874, "Drug ineffective ": 2.569663802274788, "Dyspnoea ": 2.614531148668158, "Ear pain ": 3.567740328264242, "Foetal exposure during pregnancy ": 4.142874731469938, "Folliculitis ": 87.7456234936257, "Gastrointestinal disorder ": 21.620562940783103, "Hypersensitivity ": 9.142758970373198, "Ill-defined disorder ": 47.555122045737264, "Impaired healing ": 67.00948521742104, "Infection ": 18.513057886489943, "Intentional product use issue ": 3.7152225990909153, "Irritable bowel syndrome ": 78.50191678620189, "Joint swelling ": 17.78470688299086, "Lower respiratory tract infection ": 52.15758702987159, "Medication error ": 3.6426584920878873, "Muscle injury ": 158.93044170022665, "Muscle spasticity ": 3.5369934951372546, "Nasal discomfort ": 5.109512639514701, "Nasopharyngitis ": 17.615527659664526, "Oral discomfort ": 2.751138203065422, "Ovarian cyst ": 3.990926106543789, "Pain ": 2.151737425162009, "Peripheral swelling ": 11.333138761845948, "Postoperative wound infection ": 11.793522732298658, "Premature baby ": 11.610702158928223, "Premature delivery ": 12.18509396476181, "Pruritus ": 4.717334957408566, "Rash ": 3.5304294551831634, "Sinusitis ": 40.41583815752922, "Sleep disorder ": 7.730572410623604, "Sleep disorder due to general medical condition, insomnia type ": 165.0232517719273, "Stomatitis ": 31.583404049166408, "Swelling ": 14.96385311638683, "Therapeutic product effect decreased ": 40.964734001387, "Type I hypersensitivity ": 3.2516574980273902, "Weight increased ": 13.872000698377274, "Wrong product administered ": 10.970524853087676}
\ No newline at end of file
+{"Abdominal distension": 18.80638548583657, "Abdominal pain": 4.80910070417856, "Abortion spontaneous": 41.36617298931657, "Ascites": 89.61599178002868, "Constipation": 4.236723728102946, "Haemoperitoneum": 166.83489865666, "Ovarian hyperstimulation syndrome": 1863.3713266267764, "Pelvic fluid collection": 654.9371394831838, "Pleural effusion": 5.791092086822469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/262.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/262.json
index 84ce87a2d7c..addc5e37c0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/262.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/262.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 276.43165638827986, "Colorectal adenoma ": 711.9590742088476, "Gastric polyps ": 497.3030796388903, "Hodgkin's disease ": 281.84869809354905, "Hodgkin's disease recurrent ": 1654.3781031227663, "Large intestine polyp ": 157.44829188806528, "Leukaemia ": 78.27003535870135, "Myelodysplastic syndrome ": 134.23063423773536, "Pancytopenia ": 11.617859482661585, "Pulmonary fibrosis ": 31.862610923958854, "Second primary malignancy ": 223.8543905293455}
\ No newline at end of file
+{"Anaemia": 2.460183758669652, "Conjunctivitis": 8.907819543092893, "Dermatitis": 7.445992480748502, "Dermatitis acneiform": 121.15455861306222, "Diarrhoea": 3.060436646033196, "Disease progression": 6.034844951795019, "Febrile neutropenia": 7.222634621859203, "Folliculitis": 7.631578051542689, "Haematotoxicity": 22.83093732451928, "Hypomagnesaemia": 20.937169901068646, "Hypotension": 2.18574371377473, "Interstitial lung disease": 5.76264336238349, "Leukopenia": 5.307669398609724, "Malignant neoplasm progression": 7.610465091458724, "Mucosal inflammation": 12.816613870387014, "Myelosuppression": 13.933715967767142, "Neuropathy peripheral": 8.314554560199332, "Neurotoxicity": 8.372217811797878, "Neutropenia": 11.067975875618927, "Neutrophil count decreased": 6.661346274489232, "Palmar-plantar erythrodysaesthesia syndrome": 3.2096717802750594, "Paronychia": 34.87132313773825, "Polyneuropathy": 11.867715054267329, "Rash": 2.977094618332868, "Respiratory failure": 3.6438094864431054, "Sepsis": 3.39270863404804, "Skin fissures": 25.5101441558486, "Skin lesion": 4.72614953093795, "Skin toxicity": 139.75007226018678, "Stomatitis": 8.258065864036862, "Thrombocytopenia": 3.967819235149306, "White blood cell count decreased": 4.273753045488423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/263.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/263.json
index bb13a0ca754..7a8d036a7d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/263.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/263.json
@@ -1 +1 @@
-{"Atrial fibrillation ": 9.530977583864438, "Brain natriuretic peptide increased ": 273.17683769580447, "Cardiac disorder ": 14.166109860590428, "Chest discomfort ": 14.618825869856924, "Coronary artery disease ": 31.874893640405126, "Cough ": 3.2386205941605413, "Dysphonia ": 18.24035849344978, "Dyspnoea exertional ": 22.79024278950676, "Eosinophilia ": 30.398701899431316, "Exostosis ": 169.81984144562443, "Fractional exhaled nitric oxide increased ": 13346.819653084816, "Muscle spasms ": 10.699498537987708, "Myalgia ": 3.055253169759368, "Myoglobin blood increased ": 993.1636323993032, "Nasopharyngitis ": 8.868473638625566, "Obstructive airways disorder ": 55.82454169535375, "Obstructive sleep apnoea syndrome ": 248.48900100341547, "Plantar fasciitis ": 484.1335908908842, "Pneumothorax ": 69.075898608453, "Secretion discharge ": 128.6519703463677, "Sensation of foreign body ": 100.13469470087064, "Wheezing ": 13.887793868514253}
\ No newline at end of file
+{"Abdominal distension": 2.825945050029496, "Abnormal behaviour": 12.905389238812257, "Abnormal dreams": 57.498055495201605, "Abnormal sleep-related event": 8.849465175938487, "Accommodation disorder": 2.200870636577734, "Acute myocardial infarction": 2.836886430456195, "Acute psychosis": 8.98584171860406, "Adjustment disorder": 2.0974310618034138, "Adjustment disorder with depressed mood": 2.168077461303479, "Affect lability": 6.418778886144247, "Affective disorder": 9.813886018239751, "Aggression": 20.10842703355831, "Agitated depression": 28.458013389646744, "Agitation": 7.189002809768852, "Agoraphobia": 13.309913500993988, "Alcohol abuse": 3.6238319326479775, "Alcohol interaction": 28.7329509594068, "Alcohol intolerance": 13.012596496332264, "Alcohol poisoning": 6.930295939797584, "Alcohol use": 10.90144804920299, "Alcoholism": 6.64324411259996, "Amnesia": 4.975530921435935, "Anger": 24.215432472450004, "Angina pectoris": 2.283953208187737, "Anxiety": 4.780971487727802, "Anxiety disorder": 4.780703734414313, "Apathy": 6.476834998407813, "Behaviour disorder": 3.3111966839362625, "Bipolar I disorder": 6.982177102643804, "Bipolar disorder": 8.401940997089007, "Blindness transient": 2.712778228002888, "Blood alcohol increased": 6.960079101487062, "Bradyphrenia": 2.8100834984163345, "Brief psychotic disorder with marked stressors": 36.41218226056184, "Burnout syndrome": 13.019035498520289, "Claustrophobia": 7.383475853073325, "Completed suicide": 3.953088212387927, "Constipation": 2.161841898570996, "Conversion disorder": 5.196758584192865, "Coordination abnormal": 3.986987174558451, "Crying": 9.625461237872962, "Daydreaming": 6.5248955498155246, "Decreased interest": 10.753986066006012, "Delusion": 5.598183751278615, "Dependence": 2.776768499441, "Depersonalisation/derealisation disorder": 6.006566643859938, "Depressed mood": 30.89667921573522, "Depression": 17.582043903074794, "Depression suicidal": 20.72917340619236, "Depressive symptom": 19.49443370841311, "Derealisation": 11.78000862654678, "Disease recurrence": 2.178351501359972, "Disinhibition": 2.3321110003189918, "Disorientation": 2.887547616825142, "Dissociation": 10.39283276986558, "Dissociative disorder": 5.028818683504162, "Disturbance in attention": 4.1690783089417485, "Dysgeusia": 2.2661788981383824, "Dyspepsia": 2.070130293549555, "Dysphemia": 3.146561454865356, "Emotional disorder": 11.24919960107046, "Emotional poverty": 9.420701779334095, "Emphysema": 3.239620643938389, "Epilepsy": 2.1944611036790267, "Euphoric mood": 5.370952117558132, "Fear": 6.443653022191827, "Fear of death": 2.224498456685196, "Feeling abnormal": 4.620832307074982, "Feeling drunk": 3.878582112330203, "Feeling guilty": 7.449904340325764, "Feeling of despair": 10.6610848793209, "Feeling of relaxation": 11.54939764678119, "Feelings of worthlessness": 8.168554746748166, "Flashback": 12.205967416860345, "Flat affect": 14.006863644612585, "Flatulence": 4.416052141635959, "Food aversion": 3.040702214607864, "Frustration tolerance decreased": 4.082880585803816, "Gastric mucosal lesion": 7.06368826931453, "Gingival pain": 3.854249837068328, "Gingivitis": 2.3578315615691428, "Glossitis": 2.463127733345117, "Haematochezia": 2.171829360953949, "Hallucination": 5.764329417508332, "Hallucination, auditory": 6.408686197751896, "Hallucination, visual": 3.9217213864839504, "Hallucinations, mixed": 5.490112050956109, "Hangover": 3.3336090215114127, "Homicidal ideation": 21.39171824046908, "Hostility": 9.939555826403968, "Hunger": 2.0013112574652423, "Hyperphagia": 3.619060167909501, "Hypersomnia": 2.329649766128405, "Hyperventilation": 2.2273284450188022, "Hypomania": 5.579466313599434, "Ileus": 2.1735371155199514, "Illusion": 3.2991472309901693, "Impaired driving ability": 9.715193054552389, "Impatience": 10.22638179235868, "Impulsive behaviour": 7.822267655108584, "Inappropriate affect": 3.18032499056214, "Increased appetite": 5.760277069053683, "Indifference": 8.391871354704096, "Infarction": 3.2579505493089065, "Insomnia": 5.450849072498638, "Intentional self-injury": 3.650554367449632, "Irritability": 10.08026302621828, "Judgement impaired": 4.025293448344396, "Labyrinthitis": 3.0727936042571256, "Libido decreased": 3.200033211705383, "Libido disorder": 4.353121827090177, "Libido increased": 5.563645123697841, "Listless": 2.2563440532310266, "Logorrhoea": 3.700125593768914, "Loss of consciousness": 2.099233203473885, "Loss of control of legs": 2.421090709512496, "Loss of employment": 2.603477485978756, "Loss of libido": 2.4345156562230468, "Major depression": 8.878504872299018, "Mania": 7.747715824987102, "Memory impairment": 2.9491196392023493, "Mental disorder": 7.2335849714411795, "Mental impairment": 3.59661557933796, "Mood altered": 24.553460101514187, "Mood swings": 20.842103167413807, "Morbid thoughts": 25.744439973842464, "Mouth swelling": 2.3675601942732225, "Mouth ulceration": 2.5022053444566943, "Musculoskeletal chest pain": 2.6063396790172555, "Myopia": 4.623903842525274, "Narcolepsy": 4.238925901352602, "Nausea": 2.3260616112891923, "Negative thoughts": 34.82197659870145, "Nervousness": 5.365025643749227, "Neurosis": 4.857320177532466, "Nicotine dependence": 2.912122964207541, "Nightmare": 20.71423323981967, "Nocturia": 3.3100712653689586, "Obsessive thoughts": 14.796793945329526, "Obsessive-compulsive disorder": 2.287928930852209, "Panic attack": 10.056562003766496, "Panic disorder": 9.376908754594163, "Panic reaction": 10.437362256158758, "Paranoia": 25.11822714408249, "Persecutory delusion": 4.484071041794281, "Personality change": 20.01295082233087, "Personality disorder": 7.266990683499798, "Petit mal epilepsy": 2.298467437469513, "Pharyngeal swelling": 2.0559874966711877, "Physical assault": 23.912197265454942, "Physical deconditioning": 2.844249294995618, "Pollakiuria": 2.09095290487465, "Polydipsia": 2.6919628398941797, "Polyuria": 2.662425226860789, "Poor quality sleep": 4.330357210879198, "Pre-existing condition improved": 10.136151290194698, "Prescription drug used without a prescription": 5.228148959205406, "Product availability issue": 5.336997095177058, "Product impurity": 26.225322480846494, "Product supply issue": 2.5991970940644884, "Psychiatric decompensation": 5.554664792548061, "Psychiatric symptom": 10.780484138968731, "Psychomotor hyperactivity": 2.040452614911113, "Psychotic behaviour": 9.268239703141166, "Psychotic disorder": 13.42769021943612, "Recalled product administered": 9.627420371106616, "Restlessness": 3.5071847484222296, "Retching": 2.1300898234943406, "Reversible cerebral vasoconstriction syndrome": 4.025814187258132, "Road traffic accident": 6.422506228763827, "Schizophrenia": 4.4376329733018025, "Schizophreniform disorder": 10.27620016105712, "Self esteem decreased": 7.014420232136416, "Self-destructive behaviour": 4.324109170815182, "Self-injurious ideation": 34.66549004350117, "Sleep disorder": 5.167342683377534, "Sleep talking": 4.565114610802602, "Sleep terror": 3.455257523423543, "Snoring": 2.2131542156405373, "Social avoidant behaviour": 14.43004080484692, "Somnambulism": 9.140703014946228, "Stress": 3.944521303528497, "Suicidal behaviour": 25.495078637256118, "Suicidal ideation": 27.712921871308144, "Suicide attempt": 6.454842003398301, "Suspiciousness": 10.175205060162927, "Tachyphrenia": 6.760559695497684, "Taste disorder": 2.820162667201814, "Tearfulness": 42.72366678673967, "Tension": 2.9726039916013787, "Therapeutic response unexpected": 2.291988596302023, "Thinking abnormal": 18.17537076495831, "Thirst": 2.370156846381854, "Tobacco user": 122.80309758044258, "Tobacco withdrawal symptoms": 373.64173975128256, "Tongue coated": 3.4152138190619423, "Tongue dry": 3.245085857609662, "Tongue erythema": 2.6545457502267094, "Tunnel vision": 4.359874933571327, "Urine output increased": 2.427848163239457, "Verbal abuse": 20.19304384989637, "Vestibular disorder": 2.1797978962936613, "Violence-related symptom": 54.3131394415617, "Weaning failure": 23.47599802790567, "Withdrawal syndrome": 4.110460527981488}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/264.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/264.json
index 5ad9488d965..bdbac1822d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/264.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/264.json
@@ -1 +1 @@
-{"Abdominal distension ": 42.00036500958727, "Abdominal pain ": 12.169728498754273, "Ovarian hyperstimulation syndrome ": 1086.6710242053302, "Tension ": 213.8081397999383, "Vomiting ": 2.3453199374292777}
\ No newline at end of file
+{"Alopecia": 3.398085329742896, "Gait disturbance": 3.641582031398893, "Neoplasm malignant": 10.777709124109515, "Pneumonia": 2.0334723752446258}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/265.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/265.json
index 137603343b2..9b4752068f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/265.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/265.json
@@ -1 +1 @@
-{"Actinic keratosis ": 470.24417195106304, "Acute myocardial infarction ": 2.949585464929604, "Anxiety ": 5.495613911796524, "Basal cell carcinoma ": 130.69036397828594, "Cardiac disorder ": 7.922941329325782, "Coronary artery disease ": 4.193942586660072, "Deafness ": 2.872432561702933, "Depression ": 6.547807783288016, "Diverticulitis ": 2.856407711537741, "Drug effect less than expected ": 45.5102683415831, "Drug interaction ": 3.436527011346937, "Emotional distress ": 9.361178518236857, "Erectile dysfunction ": 15.25580309549722, "Erection increased ": 10.493819189325457, "Feeling of despair ": 34.36296800537022, "Gastrooesophageal reflux disease ": 2.1911670814768214, "Hyperlipidaemia ": 4.889486707741651, "Hypersensitivity ": 2.733820285584924, "Intentional product misuse ": 2.09179562207739, "Lentigo maligna ": 1389.5915893463423, "Libido decreased ": 14.529117802560044, "Libido increased ": 56.07065819962056, "Lymphoedema ": 8.494286139900328, "Malignant melanoma ": 1030.757229570867, "Malignant melanoma in situ ": 2984.2853286942864, "Malignant melanoma stage I ": 10055.556989065251, "Malignant melanoma stage II ": 6699.82115394077, "Malignant melanoma stage III ": 3313.018374028092, "Malignant melanoma stage IV ": 2615.4602735927106, "Melanocytic naevus ": 55.802230110504254, "Melanoma recurrent ": 467.9892252687633, "Metastases to liver ": 3.038713415793136, "Metastatic malignant melanoma ": 398.3852834812421, "Neoplasm progression ": 3.9870605567468895, "Nephrolithiasis ": 2.44809137021632, "Nodular melanoma ": 683.7731034442445, "Prostate cancer ": 14.872241062500802, "Pulmonary fibrosis ": 4.237300140028569, "Sleep apnoea syndrome ": 6.563518382862385, "Squamous cell carcinoma ": 154.86879200899787, "Superficial spreading melanoma stage unspecified ": 572.684034684605, "Therapeutic response unexpected ": 5.395926926585034}
\ No newline at end of file
+{"Anaphylactic reaction": 3.6929746641694265, "Anaphylactic shock": 2.5377056795273143, "Apallic syndrome": 25.90289805646156, "Arthralgia": 2.1918877661036844, "Blister": 23.25443792693571, "Confusional state": 7.016580965850869, "Contraindicated product administered": 12.315800279230569, "Contusion": 6.856317590891874, "Drug ineffective": 2.5696447749355014, "Dyspnoea": 2.614492239553249, "Ear pain": 3.567740328264242, "Foetal exposure during pregnancy": 4.142874731469938, "Folliculitis": 87.7456234936257, "Gastrointestinal disorder": 21.61987222894837, "Hypersensitivity": 9.142758970373198, "Ill-defined disorder": 47.555122045737264, "Impaired healing": 67.00948521742104, "Infection": 18.513057886489943, "Intentional product use issue": 3.7152225990909153, "Irritable bowel syndrome": 78.50191678620189, "Joint swelling": 17.78470688299086, "Lower respiratory tract infection": 52.15758702987159, "Medication error": 3.642396554234201, "Muscle injury": 158.93044170022665, "Muscle spasticity": 3.536075937963962, "Nasal discomfort": 5.109512639514701, "Nasopharyngitis": 17.614169555464375, "Oral discomfort": 2.751138203065422, "Ovarian cyst": 3.990926106543789, "Pain": 2.151719109781053, "Peripheral swelling": 11.333138761845948, "Postoperative wound infection": 11.793522732298658, "Premature baby": 11.610702158928223, "Premature delivery": 12.18509396476181, "Pruritus": 4.717277639864911, "Rash": 3.530380847306188, "Sinusitis": 40.41583815752922, "Sleep disorder": 7.730572410623604, "Sleep disorder due to general medical condition, insomnia type": 165.0232517719273, "Stomatitis": 31.583404049166408, "Swelling": 14.96385311638683, "Therapeutic product effect decreased": 40.964734001387, "Type I hypersensitivity": 3.2516574980273902, "Weight increased": 13.872000698377274, "Wrong product administered": 10.970524853087676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/266.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/266.json
index 89e06712964..483b90c962f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/266.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/266.json
@@ -1 +1 @@
-{"Cellulitis ": 159.32369994182676}
\ No newline at end of file
+{"Acute myeloid leukaemia": 276.43165638827986, "Colorectal adenoma": 711.9590742088476, "Gastric polyps": 497.3030796388903, "Hodgkin's disease": 281.84869809354905, "Hodgkin's disease recurrent": 1654.3781031227663, "Large intestine polyp": 157.44829188806528, "Leukaemia": 78.27003535870135, "Myelodysplastic syndrome": 134.23063423773536, "Pancytopenia": 11.617859482661585, "Pulmonary fibrosis": 31.862610923958854, "Second primary malignancy": 223.8543905293455}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/267.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/267.json
index 6a45aa0fa01..1ec9420d9f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/267.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/267.json
@@ -1 +1 @@
-{"Blister ": 44.187351627185386, "Drug eruption ": 95.08060263820587, "Erythema ": 12.910407378353987, "Erythema multiforme ": 133.40075345068618, "Lymphocytic infiltration ": 2494.937340658309, "Mucosal erosion ": 2307.4006469383025, "Multiple organ dysfunction syndrome ": 88.44252085104105, "Sepsis ": 41.55283791329928, "Staphylococcal infection ": 177.1807280797498, "Staphylococcal scalded skin syndrome ": 13749.967313847352, "Toxic epidermal necrolysis ": 142.10352587642558, "Uterine haemorrhage ": 640.7550590872742}
\ No newline at end of file
+{"Atrial fibrillation": 9.530717453896855, "Brain natriuretic peptide increased": 273.17683769580447, "Cardiac disorder": 14.166109860590428, "Chest discomfort": 14.618312754986013, "Coronary artery disease": 31.874893640405126, "Cough": 3.238590558066082, "Dysphonia": 18.24035849344978, "Dyspnoea exertional": 22.79024278950676, "Eosinophilia": 30.398701899431316, "Exostosis": 169.81984144562443, "Fractional exhaled nitric oxide increased": 13346.819653084816, "Muscle spasms": 10.699498537987708, "Myalgia": 3.055253169759368, "Myoglobin blood increased": 993.1636323993032, "Nasopharyngitis": 8.867798001866827, "Obstructive airways disorder": 55.82454169535375, "Obstructive sleep apnoea syndrome": 248.48900100341547, "Plantar fasciitis": 484.1335908908842, "Pneumothorax": 69.075898608453, "Secretion discharge": 128.6519703463677, "Sensation of foreign body": 100.13469470087064, "Wheezing": 13.887241566537964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/268.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/268.json
index e1473b6923d..0a63e0f5dfb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/268.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/268.json
@@ -1 +1 @@
-{"Abdominal lymphadenopathy ": 8.69519941681243, "Abdominal mass ": 5.354082685958196, "Abdominal tenderness ": 3.1960376968007145, "Abscess ": 2.648336107217271, "Abscess drainage ": 11.732023580390669, "Acanthosis ": 17.372580702754462, "Acid fast bacilli infection ": 34.195124713376366, "Acinetobacter infection ": 17.05424707425568, "Actinic keratosis ": 6.885296488905276, "Acute graft versus host disease ": 105.31685171796516, "Acute graft versus host disease in intestine ": 107.34010978057256, "Acute graft versus host disease in liver ": 100.81155542103345, "Acute graft versus host disease in skin ": 104.30356876756905, "Acute leukaemia ": 2.14318407398394, "Acute lymphocytic leukaemia ": 2.974401495734704, "Acute lymphocytic leukaemia recurrent ": 12.238778024425748, "Acute myeloid leukaemia ": 4.451723580644136, "Acute myeloid leukaemia recurrent ": 21.38704136798354, "Acute respiratory distress syndrome ": 2.629765594785154, "Adenoviral haemorrhagic cystitis ": 55.0830766267274, "Adenoviral hepatitis ": 29.180243734783044, "Adenovirus infection ": 41.71473126444578, "Adult T-cell lymphoma/leukaemia ": 12.747335960480354, "Aeromonas infection ": 24.17064032327501, "Alanine aminotransferase abnormal ": 2.163019012385277, "Alpha haemolytic streptococcal infection ": 14.534236189100652, "Alternaria infection ": 43.93499604294308, "Alveolar proteinosis ": 23.646736010988448, "American trypanosomiasis ": 40.18468625699976, "Amniotic cavity infection ": 6.96783505374988, "Anaplastic large cell lymphoma T- and null-cell types ": 24.40459777201293, "Aneurysm ": 3.7648758848386654, "Anogenital warts ": 6.836616304601608, "Antinuclear antibody positive ": 2.3375258538363157, "Anuria ": 3.3926519660750487, "Apgar score low ": 3.683806357713131, "Aplasia pure red cell ": 4.124159290574716, "Aplastic anaemia ": 8.521443350858325, "Areflexia ": 2.025468324129245, "Arterial disorder ": 7.349033329217061, "Arteriosclerosis ": 2.2435332283671205, "Arthropod bite ": 5.612405568893792, "Ascites ": 2.0196798875121744, "Aspergillus infection ": 23.248633266444266, "Atypical mycobacterial infection ": 7.700720085272615, "Autoimmune haemolytic anaemia ": 10.651170440571963, "Azotaemia ": 6.221864151678105, "B-cell lymphoma ": 25.711936006940807, "BK polyomavirus test positive ": 51.84362451150208, "BK virus infection ": 58.91817623696521, "Bacillary angiomatosis ": 100.68383597702528, "Bacteraemia ": 5.058912011796364, "Bacterial infection ": 6.485995642795644, "Bacterial sepsis ": 6.363071184267494, "Basal cell carcinoma ": 9.920464538804046, "Behcet's syndrome ": 34.682646402431935, "Bile duct stone ": 2.1814425739561663, "Bladder cancer recurrent ": 13.669122458058936, "Bladder irritation ": 10.79089490394596, "Bladder neoplasm surgery ": 40.06317628271132, "Bladder transitional cell carcinoma ": 15.400606430105444, "Blast cell count increased ": 4.113041541759277, "Blast cells present ": 7.083545135005069, "Blindness cortical ": 13.576604721972078, "Blood albumin decreased ": 2.307473057066554, "Blood beta-D-glucan increased ": 17.381817218889044, "Blood bilirubin increased ": 3.449422219636036, "Blood creatinine increased ": 5.633299543175313, "Blood culture positive ": 2.656992934445338, "Blood immunoglobulin G decreased ": 9.82352114689494, "Blood immunoglobulin G increased ": 3.202841931905586, "Blood lactate dehydrogenase increased ": 4.856177633997981, "Blood parathyroid hormone decreased ": 5.311412088344321, "Blood stem cell transplant failure ": 186.82590107433472, "Blood urea increased ": 3.679900669010012, "Bone cyst ": 6.870552093900566, "Bone erosion ": 3.907270422327623, "Bone marrow failure ": 4.3489546215059045, "Bone marrow transplant ": 4.330583318151476, "Bone marrow transplant rejection ": 32.51709629141625, "Bowen's disease ": 19.65715534366673, "Brain abscess ": 16.257647498583673, "Brain herniation ": 3.249463682412788, "Brain oedema ": 5.224849309408813, "Bronchiolitis obliterans syndrome ": 31.003287276204, "Bronchopulmonary aspergillosis ": 18.21929512446778, "Burkholderia cepacia complex infection ": 24.746196164018816, "Burkitt's lymphoma ": 17.537664755469716, "C-reactive protein increased ": 2.85805471323886, "CD4 lymphocytes decreased ": 3.140671820463055, "CSF pressure increased ": 9.170624640108924, "CSF protein increased ": 9.589208678323471, "CSF test abnormal ": 10.265377362486792, "CSF virus identified ": 51.96128368763689, "Cachexia ": 2.657427595565616, "Calcineurin inhibitor induced pain syndrome ": 92.2405300457676, "Cancer surgery ": 11.393975614171238, "Candida infection ": 3.49997986428728, "Candida pneumonia ": 34.3699203936446, "Capillary disorder ": 18.470432833946195, "Capillary leak syndrome ": 3.719432260322348, "Cardiomegaly ": 2.350795836701095, "Cat scratch disease ": 26.39201935018955, "Central nervous system lesion ": 7.94438388864027, "Central nervous system lymphoma ": 22.70045771742604, "Cerebral atrophy ": 2.428905173785714, "Cerebral toxoplasmosis ": 11.568456559269825, "Cerebrovascular disorder ": 2.3375258538363157, "Chimerism ": 43.03389933184699, "Cholangitis sclerosing ": 3.717529831292673, "Chorioretinopathy ": 16.615393731135896, "Chronic allograft nephropathy ": 97.94922513786184, "Chronic graft versus host disease ": 141.35209015176216, "Chronic graft versus host disease in intestine ": 94.8951821043728, "Chronic graft versus host disease in liver ": 123.3465556989358, "Chronic graft versus host disease in skin ": 108.35174259408711, "Chronic graft versus host disease oral ": 27.299926195105403, "Chronic hepatitis ": 5.617285407263406, "Chronic hepatitis C ": 4.884481624338068, "Chronic myeloid leukaemia ": 3.71340496791283, "Chronic spontaneous urticaria ": 14.607586555487766, "Clear cell renal cell carcinoma ": 11.254336318265082, "Clostridium difficile colitis ": 2.148039959202394, "Colectomy ": 6.0392319886703385, "Complications of bone marrow transplant ": 62.50440530533879, "Complications of transplanted kidney ": 68.93851548735573, "Complications of transplanted lung ": 118.51793630474916, "Computerised tomogram abnormal ": 5.873925952650038, "Concomitant disease aggravated ": 2.173669508551286, "Concomitant disease progression ": 7.485942720321299, "Congenital aplasia ": 2.907098437437819, "Coombs positive haemolytic anaemia ": 25.76180970303147, "Creatinine renal clearance decreased ": 2.339904087999549, "Cryptococcosis ": 21.697413017966483, "Cryptosporidiosis infection ": 22.85363226950199, "Cushing's syndrome ": 2.193045275967615, "Cushingoid ": 9.257074000552214, "Cutaneous T-cell lymphoma ": 19.76893075099348, "Cystitis haemorrhagic ": 22.836400861869787, "Cystitis viral ": 20.80635791361986, "Cytomegalovirus chorioretinitis ": 14.119206796792126, "Cytomegalovirus colitis ": 20.29013916433593, "Cytomegalovirus enterocolitis ": 7.936084852724999, "Cytomegalovirus gastritis ": 16.554402454853285, "Cytomegalovirus gastroenteritis ": 23.76101966861085, "Cytomegalovirus gastrointestinal infection ": 25.48893380412885, "Cytomegalovirus hepatitis ": 11.74105709348279, "Cytomegalovirus infection ": 33.98016532485754, "Cytomegalovirus infection reactivation ": 39.31315671690326, "Cytomegalovirus test ": 37.5374669093521, "Cytomegalovirus test positive ": 27.329066846936666, "Cytomegalovirus viraemia ": 22.08102360659077, "Cytopenia ": 2.3479491057831146, "Debridement ": 32.61734257162428, "Demyelinating polyneuropathy ": 3.55634035998865, "Demyelination ": 2.552343402121895, "Dengue haemorrhagic fever ": 51.84362451150208, "Dermatitis atopic ": 3.684787954937666, "Dermatitis exfoliative generalised ": 3.272540011830775, "Dermatomyositis ": 3.574179365044152, "Device related infection ": 2.1714254147972483, "Device related sepsis ": 3.856704800362588, "Dialysis ": 4.066594532207034, "Diarrhoea haemorrhagic ": 2.7545128620951265, "Diffuse alveolar damage ": 10.22910740326085, "Diffuse large B-cell lymphoma ": 10.941994272265118, "Diffuse large B-cell lymphoma stage IV ": 23.100132546211896, "Disease recurrence ": 5.8191837501328845, "Disseminated Bacillus Calmette-Guerin infection ": 12.059808396897823, "Disseminated aspergillosis ": 12.40905736141155, "Disseminated cryptococcosis ": 16.613248944557963, "Disseminated intravascular coagulation ": 3.1366446045320235, "Disseminated tuberculosis ": 11.277980945457127, "Diverticular perforation ": 2.311585052776248, "Drug ineffective for unapproved indication ": 3.2554709414612835, "Drug interaction ": 2.9537301258746105, "Drug intolerance ": 2.4100663860778337, "Drug level above therapeutic ": 2.120592527428202, "Drug level below therapeutic ": 2.767000487786216, "Drug level decreased ": 6.808993477372205, "Drug level fluctuating ": 5.701800007027876, "Drug level increased ": 7.454684392665531, "Drug resistance ": 4.202769455309068, "Eastern Cooperative Oncology Group performance status worsened ": 9.006529106562589, "Eczema herpeticum ": 6.081173944801256, "Electrocardiogram ST segment depression ": 2.116441239323388, "Electroencephalogram abnormal ": 2.8085093446800258, "Empyema ": 2.68752793048808, "Encephalitis ": 3.292285880415402, "Encephalitis cytomegalovirus ": 29.119188716507157, "Encephalitis herpes ": 20.50936311785056, "Encephalitis viral ": 15.433221330210968, "Encephalopathy ": 3.1162661956165523, "End stage renal disease ": 4.222335440280807, "Endocarditis ": 2.934373725394736, "Endotracheal intubation ": 2.610026620402992, "Engraft failure ": 46.17408515418877, "Engraftment syndrome ": 22.777587450676133, "Enterobacter infection ": 5.4239941403072605, "Enterococcal bacteraemia ": 5.221644009467364, "Enterococcal infection ": 11.269417135707396, "Enterococcal sepsis ": 11.18912388056708, "Enthesopathy ": 3.7665746743527664, "Epstein-Barr viraemia ": 32.3368581942304, "Epstein-Barr virus antibody positive ": 20.47225462023441, "Epstein-Barr virus associated lymphoma ": 27.08098622113249, "Epstein-Barr virus associated lymphoproliferative disorder ": 74.86607433169681, "Epstein-Barr virus infection ": 63.28097470157935, "Epstein-Barr virus infection reactivation ": 21.55941880681132, "Epstein-Barr virus test positive ": 15.944615154789318, "Erythrodermic psoriasis ": 7.892118892290502, "Escherichia bacteraemia ": 2.58837329841536, "Escherichia infection ": 8.968810489781816, "Escherichia sepsis ": 2.951286134139187, "Escherichia urinary tract infection ": 2.0282981349657483, "Evans syndrome ": 18.358339012790807, "Exophthalmos ": 2.371536382911132, "Extensor plantar response ": 4.021691350866382, "Extranodal marginal zone B-cell lymphoma ": 13.908532496924847, "Fear of injection ": 6.778857227510716, "Febrile neutropenia ": 2.6003322856078728, "Fibroadenoma of breast ": 34.306180628015696, "Focal segmental glomerulosclerosis ": 39.97405163896738, "Foetal disorder ": 5.291213351409764, "Foetal distress syndrome ": 4.136832615598153, "Foetal growth restriction ": 5.516318022488767, "Foetal heart rate deceleration abnormality ": 5.995518120404044, "Fungaemia ": 8.0409854190027, "Fungal infection ": 5.267264077082234, "Fungal sepsis ": 10.168812572023446, "Fungal skin infection ": 3.721347108102508, "Fungal test positive ": 11.222000889169353, "Fusarium infection ": 25.438734657666668, "Gastric mucosal lesion ": 4.3973199591706, "Gastroenteritis adenovirus ": 24.366343960983684, "Gastroenteritis norovirus ": 7.3901245090569585, "Gastrointestinal infection ": 2.0550829578357783, "Gastrointestinal mucosal disorder ": 9.960250042807528, "Generalised oedema ": 2.9182001230267924, "Gestational hypertension ": 3.70354138043252, "Gingival hypertrophy ": 55.07368826719517, "Gingival swelling ": 2.4974080511013823, "Gingivectomy ": 175.641602262016, "Glomerular filtration rate decreased ": 3.0128829487803674, "Glomerular vascular disorder ": 39.54997060207162, "Glomerulonephritis ": 5.575496494992393, "Glomerulonephritis membranoproliferative ": 11.342496122696632, "Glomerulonephritis membranous ": 15.394041420367198, "Glomerulonephritis minimal lesion ": 20.206974824428503, "Glomerulonephropathy ": 40.862364270202725, "Glomerulosclerosis ": 30.55514831674318, "Gouty tophus ": 24.132042619502297, "Graft loss ": 61.00097059465603, "Graft versus host disease ": 74.75093640227017, "Graft versus host disease in eye ": 56.84382199786557, "Graft versus host disease in gastrointestinal tract ": 94.0958374696237, "Graft versus host disease in liver ": 92.05462740404153, "Graft versus host disease in lung ": 48.49454091149225, "Graft versus host disease in skin ": 89.035771174271, "Granuloma ": 3.484937698625681, "Granuloma skin ": 7.948138457852394, "Granulomatosis with polyangiitis ": 3.9626572701266256, "Growth retardation ": 6.521487594312666, "Guttate psoriasis ": 4.641848162781707, "H1N1 influenza ": 5.092930206166092, "Haematocrit decreased ": 2.058880996940464, "Haematuria ": 3.088571850930101, "Haemodialysis ": 17.70164133292436, "Haemolysis ": 5.102358584766035, "Haemolytic anaemia ": 2.8270629597923365, "Haemolytic uraemic syndrome ": 28.36188133278254, "Haemophagocytic lymphohistiocytosis ": 16.227763247282358, "Haemorrhage intracranial ": 2.1011426325548053, "Haptoglobin decreased ": 9.716280946140808, "Head deformity ": 11.411447123407187, "Heart transplant rejection ": 112.14219591799444, "Hepatic failure ": 2.2974582072651035, "Hepatic fibrosis ": 12.088102766815824, "Hepatic lesion ": 2.170405411874695, "Hepatic mass ": 2.709496112152312, "Hepatic necrosis ": 3.517173853175943, "Hepatitis B ": 4.459396790664978, "Hepatitis B reactivation ": 7.733244841865264, "Hepatitis B surface antigen positive ": 9.287395609739743, "Hepatitis E ": 16.649135311217098, "Hepatitis viral ": 8.729161066821439, "Hepatomegaly ": 2.874387740251926, "Hepatosplenomegaly ": 9.01721319472986, "Herpes simplex ": 3.907995052831402, "Herpes virus infection ": 3.642620548615077, "Herpes zoster disseminated ": 5.826038030094606, "Hilar lymphadenopathy ": 7.195542713521421, "Hirsutism ": 32.54001191164458, "Hodgkin's disease ": 7.614481942442609, "Human ehrlichiosis ": 237.12043410869265, "Human herpes virus 6 serology positive ": 12.68645977088494, "Human herpesvirus 6 infection ": 15.831105175995434, "Human herpesvirus 6 infection reactivation ": 8.064440303491313, "Human herpesvirus 8 infection ": 51.412879327651325, "Human polyomavirus infection ": 55.181797551657, "Hydrocephalus ": 4.183203902089193, "Hydronephrosis ": 4.09998789009813, "Hyperbilirubinaemia ": 2.375467267908798, "Hyperkeratosis ": 3.7643061213894815, "Hypertension ": 2.266685107846941, "Hypertensive encephalopathy ": 6.986469870744432, "Hypertrichosis ": 17.890695130430036, "Hypervolaemia ": 2.10017371773616, "Hypoalbuminaemia ": 6.625031317786491, "Hypogammaglobulinaemia ": 6.800434074061824, "Hypomagnesaemia ": 2.3986499899020566, "Hypoproteinaemia ": 4.0967528223071135, "Hyporeflexia ": 2.313974468179848, "Idiopathic intracranial hypertension ": 5.417700424104092, "Idiopathic pneumonia syndrome ": 45.1671712987872, "IgA nephropathy ": 4.513350701188741, "Immunosuppressant drug level decreased ": 28.634089784155982, "Immunosuppressant drug level increased ": 60.65172255742176, "Immunosuppression ": 7.295618862887299, "Incorrect dosage administered ": 2.3758669490067703, "Infected skin ulcer ": 3.918392019208175, "Infection ": 2.4107438407024526, "Infection reactivation ": 11.158362676158124, "Infectious pleural effusion ": 3.4932304234943587, "Intermittent claudication ": 2.001356559354298, "Intervertebral discitis ": 2.978480134782923, "Intestinal resection ": 4.096622405457169, "Intracranial mass ": 5.063869869074814, "Intracranial pressure increased ": 4.675219172623604, "Intravascular haemolysis ": 6.554110667916862, "Iron overload ": 5.160554024960483, "JC virus infection ": 11.759142589694063, "Joint ankylosis ": 5.506056138313052, "Juvenile idiopathic arthritis ": 5.812208673927205, "Kaposi's sarcoma ": 44.73917367212656, "Keratitis ": 2.231529110007328, "Kidney fibrosis ": 32.48889372031274, "Kidney transplant rejection ": 73.96579122334492, "Klebsiella bacteraemia ": 6.348507675249137, "Klebsiella infection ": 10.273127245958964, "Laparotomy ": 10.021153245903974, "Large intestinal ulcer ": 2.872862349479948, "Large intestine perforation ": 2.3504833974897603, "Legionella infection ": 17.36339163904472, "Lesion excision ": 33.332111642137754, "Leukaemia recurrent ": 20.49041436516287, "Leukocytosis ": 2.2306462037658674, "Leukoencephalopathy ": 12.033758421331695, "Lichenification ": 31.858958687588725, "Lipids increased ": 5.762445574042518, "Lipohypertrophy ": 3.2624178034770117, "Listeriosis ": 6.404523061228796, "Liver abscess ": 3.845771368460654, "Liver transplant ": 2.644481403947702, "Liver transplant rejection ": 78.19263660444946, "Low birth weight baby ": 9.64185386958937, "Lung abscess ": 3.272928013394609, "Lung consolidation ": 5.607872863658767, "Lung infiltration ": 6.97723086569875, "Lung transplant rejection ": 70.52548890089882, "Lupus nephritis ": 6.179127761541515, "Lymphadenectomy ": 16.386548271681225, "Lymphadenitis ": 2.145858929418475, "Lymphadenopathy mediastinal ": 5.219241904700827, "Lymphocele ": 23.76558147673437, "Lymphocyte count decreased ": 2.5497531584436124, "Lymphocyte count increased ": 3.888209613798106, "Lymphocyte morphology abnormal ": 8.505879054879587, "Lymphocytic infiltration ": 11.031136436099022, "Lymphoma ": 4.771217099927423, "Lymphopenia ": 2.711468098947762, "Lymphoproliferative disorder ": 34.304720264822684, "Magnetic resonance imaging abnormal ": 3.887643206601181, "Magnetic resonance imaging head abnormal ": 9.77919968973547, "Malignant fibrous histiocytoma ": 43.63452627638474, "Marrow hyperplasia ": 5.838752940578392, "Mass ": 2.51918533570359, "Mean cell haemoglobin concentration decreased ": 3.489602736136421, "Mean platelet volume decreased ": 6.875277705809002, "Mechanical ventilation ": 10.72605917659054, "Mediastinitis ": 10.645728315859296, "Meningism ": 2.3666851241929243, "Meningitis cryptococcal ": 7.022672108143361, "Meningitis tuberculous ": 7.09766852481623, "Metapneumovirus infection ": 12.700526944892667, "Metastases to lymph nodes ": 3.0571696577427687, "Microangiopathic haemolytic anaemia ": 33.424592404565416, "Microangiopathy ": 10.988982327127031, "Microsporidia infection ": 26.45077194744592, "Monocyte count decreased ": 4.361474125001556, "Mouth ulceration ": 2.444316950741806, "Mucocutaneous leishmaniasis ": 157.71453839144132, "Mucormycosis ": 27.321440802620867, "Mucosal erosion ": 5.18729890679847, "Mucosal inflammation ": 3.784468538439572, "Mucosal ulceration ": 7.719240126966397, "Multiple organ dysfunction syndrome ": 7.57077338595741, "Mycobacterial infection ": 7.85459758922767, "Mycobacterium avium complex infection ": 4.219271145249596, "Mycobacterium chelonae infection ": 26.67661126509181, "Mycobacterium kansasii infection ": 16.892041736139973, "Myelodysplastic syndrome ": 4.769597012916603, "Myeloid leukaemia ": 9.022980588351649, "Myoglobin blood increased ": 2.556921231771057, "Myoglobinuria ": 9.311895683784783, "Myopathy ": 4.930714607294435, "Myopathy toxic ": 26.292027135629706, "Nail dystrophy ": 7.879142184593298, "Nasal septum deviation ": 4.62945995029691, "Natural killer cell count increased ": 137.52493547373126, "Necrosis ": 3.5087481883914693, "Necrotising fasciitis ": 6.421113608871963, "Neoplasm recurrence ": 2.972663130440259, "Neoplasm skin ": 10.04857319529661, "Nephrectomy ": 12.490699521236138, "Nephropathy ": 2.52099223713054, "Nephropathy toxic ": 29.705721354069723, "Nephrotic syndrome ": 15.74217162384833, "Nephroureterectomy ": 280.08380551729664, "Neuroendocrine carcinoma of the skin ": 13.375418742024529, "Neurological decompensation ": 5.577161593119884, "Neurotoxicity ": 7.172991543039554, "Neutrophil count increased ": 2.397771287751376, "Nocardiosis ": 51.32691663873011, "Nodule ": 3.1848880448234653, "Non-Hodgkin's lymphoma ": 6.213887951092764, "Normal newborn ": 5.110929506265864, "Normocytic anaemia ": 2.062297079962748, "Norovirus test positive ": 15.598157148618046, "Obliterative bronchiolitis ": 45.742529321595576, "Oesophageal candidiasis ": 3.2040538992900043, "Oliguria ": 5.668743296635772, "Opportunistic infection ": 4.641848162781707, "Oral disorder ": 2.5797796343472803, "Oral lichen planus ": 4.453144601826418, "Oral mucosa erosion ": 3.3084285036482166, "Organising pneumonia ": 3.223942193906272, "Osmotic demyelination syndrome ": 12.14502353871776, "Osteolysis ": 5.808811301899119, "Osteoporotic fracture ": 3.12623403840072, "Ototoxicity ": 3.029860238373207, "Pancytopenia ": 3.025415179280812, "Panniculitis ": 5.917115874017986, "Papillary thyroid cancer ": 11.12658135469201, "Papilloedema ": 4.102515332321778, "Papilloma viral infection ": 5.264544089488227, "Papule ": 2.8982022379645214, "Parainfluenzae virus infection ": 13.08529974351386, "Paraparesis ": 2.063595664184878, "Paroxysmal nocturnal haemoglobinuria ": 11.089954322061155, "Partial seizures ": 3.144065161274676, "Parvovirus B19 infection ": 23.78075284200802, "Pathogen resistance ": 2.2805934677175537, "Pelvic fracture ": 2.4010761102963984, "Periodontitis ": 3.0940854671494176, "Peripheral T-cell lymphoma unspecified ": 20.616843425485712, "Peritonitis ": 3.7985126196202894, "Peritonitis bacterial ": 2.959632448715252, "Phaeohyphomycosis ": 35.59377919423019, "Photodermatosis ": 8.17574779963936, "Pityriasis rubra pilaris ": 10.61846079233384, "Plasmablastic lymphoma ": 27.7436503463608, "Plasmacytoma ": 8.278193627554993, "Pleocytosis ": 7.051373543851954, "Pleural effusion ": 2.0851520573548767, "Pneumatosis intestinalis ": 9.067916952336407, "Pneumocystis jirovecii infection ": 10.4268682501703, "Pneumocystis jirovecii pneumonia ": 8.921894943169129, "Pneumomediastinum ": 9.7615020212804, "Pneumonia bacterial ": 5.559877541838443, "Pneumonia cytomegaloviral ": 33.7268938429351, "Pneumonia fungal ": 9.221449806012398, "Pneumonia klebsiella ": 5.1339691143129, "Pneumonia legionella ": 5.764023370367196, "Pneumonia pseudomonal ": 8.42508037930584, "Pneumonia staphylococcal ": 2.5929868379700505, "Pneumonia viral ": 5.06121999215259, "Pneumothorax ": 2.1047257618856654, "Polycythaemia ": 3.247333717713528, "Polymyositis ": 2.757970477445421, "Polyomavirus viraemia ": 77.04412280631654, "Polyomavirus-associated nephropathy ": 24.51253409160969, "Porokeratosis ": 27.488116975361876, "Post transplant lymphoproliferative disorder ": 114.75031611108524, "Posterior reversible encephalopathy syndrome ": 32.447985184985896, "Pre-eclampsia ": 5.486072397036593, "Pre-existing condition improved ": 3.332431046406912, "Premature baby ": 4.90229613346597, "Premature delivery ": 2.150737763809231, "Premature labour ": 8.113477383031176, "Product use in unapproved indication ": 3.803719740852984, "Progressive multifocal leukoencephalopathy ": 4.265587372359194, "Protein urine present ": 5.859650477086315, "Protein-losing gastroenteropathy ": 8.765183839157324, "Proteinuria ": 7.094904369188273, "Pseudolymphoma ": 20.223403042777708, "Pseudomonal bacteraemia ": 6.206217235159014, "Pseudomonal sepsis ": 11.934815144922675, "Pseudomonas infection ": 11.263638566533045, "Psoriasis ": 4.6271820930632535, "Psoriasis area severity index increased ": 17.632460627415607, "Pulmonary alveolar haemorrhage ": 2.7187848792074947, "Pulmonary haemorrhage ": 2.91993146703286, "Pulmonary mass ": 3.1334319840368265, "Pulmonary tuberculosis ": 7.811291026254513, "Purulence ": 4.030962722080242, "Purulent discharge ": 7.729516825093644, "Pustular psoriasis ": 7.25869109077661, "Pustule ": 2.552636511039637, "Pyelonephritis ": 2.107859766475213, "Pyoderma gangrenosum ": 12.181846287852244, "Pyogenic granuloma ": 34.19241473878414, "Quadriplegia ": 2.406121313082974, "Rales ": 3.092285092940189, "Rebound effect ": 6.328287365571042, "Red blood cell abnormality ": 5.920040566231614, "Red blood cell schistocytes present ": 80.64849201795718, "Red blood cell sedimentation rate abnormal ": 4.0826164131228655, "Red blood cell sedimentation rate increased ": 4.484392485965304, "Removal of renal transplant ": 79.03874336037859, "Renal arteriosclerosis ": 38.91404680232824, "Renal disorder ": 2.212985809177336, "Renal impairment ": 5.161179064670264, "Renal mass ": 6.632554570557144, "Renal transplant ": 4.454446597115008, "Renal transplant failure ": 87.31339586387926, "Renal tubular atrophy ": 46.32015292922189, "Renal tubular disorder ": 2.23838692003034, "Renal tubular injury ": 11.538938045787262, "Renal tubular necrosis ": 3.870891827661013, "Renal vessel disorder ": 54.98110614762541, "Respiratory failure ": 3.2409016477870294, "Respiratory syncytial virus infection ": 2.3798985565231137, "Respiratory tract infection viral ": 2.6926854621741496, "Reticulocyte count decreased ": 5.89687573917482, "Reticulocyte count increased ": 11.142792737758612, "Retinal depigmentation ": 19.471767814740115, "Retinitis ": 7.967106320598573, "Reversible cerebral vasoconstriction syndrome ": 3.1630603196520526, "Rhabdomyolysis ": 3.356471362435037, "Rheumatoid factor negative ": 16.064130920802604, "Rheumatoid nodule ": 3.744934440190772, "Rhodococcus infection ": 31.862419839963398, "Salmonellosis ": 6.850307006267866, "Sarcoma ": 4.945154177224769, "Scedosporium infection ": 33.64824245304187, "Scleroderma ": 10.63797234053519, "Sebaceous hyperplasia ": 48.97799942767748, "Secondary immunodeficiency ": 14.867153340335117, "Sepsis ": 4.003162685174839, "Septic embolus ": 7.197126617589531, "Septic shock ": 4.027269160293017, "Serum ferritin decreased ": 2.918959635759406, "Serum ferritin increased ": 6.538480860612826, "Skin atrophy ": 5.612532335146753, "Skin cancer ": 3.401106055511613, "Skin graft ": 17.9793872311801, "Skin hyperpigmentation ": 4.061092736016876, "Skin infection ": 4.12829917775097, "Skin injury ": 3.912370812095685, "Skin lesion ": 6.12849593283056, "Skin mass ": 10.966927843030064, "Skin necrosis ": 4.20122392047092, "Skin neoplasm excision ": 41.583784877478905, "Skin papilloma ": 7.077568314885081, "Skin plaque ": 11.013931144418216, "Skin ulcer ": 3.51591796035077, "Small for dates baby ": 6.89033277485059, "Smooth muscle cell neoplasm ": 138.06063727027387, "Soft tissue infection ": 8.468403573382417, "Splenectomy ": 4.200036732450712, "Splenic abscess ": 11.400612544129594, "Splenomegaly ": 4.990282906307159, "Squamous cell carcinoma ": 17.027931354295355, "Squamous cell carcinoma of skin ": 13.3252864784407, "Squamous cell carcinoma of the oral cavity ": 15.540744090947078, "Squamous cell carcinoma of the tongue ": 14.176702104609326, "Staphylococcal bacteraemia ": 6.536825229733476, "Staphylococcal infection ": 5.188843893456624, "Staphylococcal sepsis ": 6.235923952087454, "Stem cell transplant ": 12.310502992083835, "Stenotrophomonas infection ": 3.41461728012077, "Steroid diabetes ": 19.856322437971297, "Still's disease ": 6.344682318531322, "Streptococcal infection ": 4.516795844731306, "Streptococcal sepsis ": 4.707114622703459, "Subcutaneous abscess ": 3.410559908613433, "Sweat gland tumour ": 32.97253230584527, "Symptom recurrence ": 2.9553198714604143, "Systemic candida ": 7.609906660909628, "Systemic mycosis ": 10.44367546239378, "T-cell lymphoma ": 15.05023861167756, "Therapeutic product effect variable ": 4.03073006221037, "Therapeutic response decreased ": 4.000878507081898, "Therapy non-responder ": 3.615980035467321, "Thrombotic microangiopathy ": 32.49491132786436, "Thrombotic thrombocytopenic purpura ": 8.255537601194238, "Thyroid cancer metastatic ": 20.150005591740904, "Thyroidectomy ": 7.759749728517889, "Tongue ulceration ": 5.566217015564675, "Toxic encephalopathy ": 10.74354189057058, "Toxoplasmosis ": 16.46679768892643, "Transitional cell carcinoma ": 23.565271641428645, "Transplant dysfunction ": 22.76523346631521, "Transplant failure ": 20.50265647936352, "Transplant rejection ": 28.385830549513955, "Treatment failure ": 3.721941170611354, "Tuberculosis ": 4.488949391673467, "Tubulointerstitial nephritis ": 2.126574854698262, "Ulcer ": 4.371180005063804, "Ureteric stenosis ": 14.213455252192364, "Urinary occult blood positive ": 6.6964134246138, "Urinary tract infection bacterial ": 4.393551872612246, "Urinary tract obstruction ": 2.709496112152312, "Urine output decreased ": 3.2825942346689785, "VIth nerve paralysis ": 2.0273823482730573, "Varicella zoster virus infection ": 19.023282950213, "Vasogenic cerebral oedema ": 9.412007363956626, "Venoocclusive disease ": 10.366313850738765, "Venoocclusive liver disease ": 5.527681596705299, "Viraemia ": 4.528090599267239, "Viral haemorrhagic cystitis ": 51.13065306067522, "Viral infection ": 3.112165841892755, "Viral test positive ": 38.273802464270375, "Visceral leishmaniasis ": 35.85207887738773, "West Nile viral infection ": 40.44515392850197, "Wound dehiscence ": 3.423193442333331}
\ No newline at end of file
+{"Abdominal distension": 42.00036500958727, "Abdominal pain": 12.169728498754273, "Ovarian hyperstimulation syndrome": 1086.6710242053302, "Tension": 213.8081397999383, "Vomiting": 2.345288301715508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/269.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/269.json
index 98199bcc3dd..d582fbee941 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/269.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/269.json
@@ -1 +1 @@
-{"Acute kidney injury ": 5.785850433581323, "Adenovirus infection ": 178.91709454538486, "Blood creatinine increased ": 5.193897657878051, "Cytomegalovirus colitis ": 162.29863038383192, "Cytomegalovirus infection ": 41.440928314154455, "Cytomegalovirus infection reactivation ": 66.90277757766741, "Disease progression ": 2.623364475754772, "Drug ineffective ": 4.648242467684529, "Drug ineffective for unapproved indication ": 66.20740585584294, "Drug resistance ": 66.19412812334754, "Graft versus host disease in gastrointestinal tract ": 145.9283893197127, "Haematuria ": 4.976482507869688, "Hemiparesis ": 11.18727847729707, "Multiple-drug resistance ": 60.847392246304615, "Myelosuppression ": 4.7153669730625785, "Nephropathy toxic ": 105.4011116265018, "Neutropenia ": 2.1392633581911373, "Off label use ": 8.175209875911749, "Pancytopenia ": 8.245672673576786, "Pathogen resistance ": 29.723942328537767, "Polyomavirus-associated nephropathy ": 175.93598661295954, "Product use in unapproved indication ": 4.559843719411307, "Product use issue ": 7.898429186621002, "Progressive multifocal leukoencephalopathy ": 88.93765803221706, "Renal failure ": 2.290129625039424, "Renal impairment ": 14.528366705436037, "Respiratory failure ": 7.203238343053603, "Uveitis ": 50.39468728080397}
\ No newline at end of file
+{"Actinic keratosis": 470.24417195106304, "Acute myocardial infarction": 2.949585464929604, "Anxiety": 5.495613911796524, "Basal cell carcinoma": 130.69036397828594, "Cardiac disorder": 7.922941329325782, "Coronary artery disease": 4.193942586660072, "Deafness": 2.872432561702933, "Depression": 6.547807783288016, "Diverticulitis": 2.856407711537741, "Drug effect less than expected": 45.5102683415831, "Drug interaction": 3.436527011346937, "Emotional distress": 9.361178518236857, "Erectile dysfunction": 15.25580309549722, "Erection increased": 10.493819189325457, "Feeling of despair": 34.36296800537022, "Gastrooesophageal reflux disease": 2.1911670814768214, "Hyperlipidaemia": 4.889486707741651, "Hypersensitivity": 2.733820285584924, "Intentional product misuse": 2.09179562207739, "Lentigo maligna": 1389.5915893463423, "Libido decreased": 14.529117802560044, "Libido increased": 56.07065819962056, "Lymphoedema": 8.494286139900328, "Malignant melanoma": 1030.757229570867, "Malignant melanoma in situ": 2984.2853286942864, "Malignant melanoma stage I": 10055.556989065251, "Malignant melanoma stage II": 6699.82115394077, "Malignant melanoma stage III": 3313.018374028092, "Malignant melanoma stage IV": 2615.4602735927106, "Melanocytic naevus": 55.802230110504254, "Melanoma recurrent": 467.9892252687633, "Metastases to liver": 3.038713415793136, "Metastatic malignant melanoma": 398.3852834812421, "Neoplasm progression": 3.9870605567468895, "Nephrolithiasis": 2.447686639967041, "Nodular melanoma": 683.7731034442445, "Prostate cancer": 14.872241062500802, "Pulmonary fibrosis": 4.237300140028569, "Sleep apnoea syndrome": 6.560609921974558, "Squamous cell carcinoma": 154.86879200899787, "Superficial spreading melanoma stage unspecified": 572.684034684605, "Therapeutic response unexpected": 5.395926926585034}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/27.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/27.json
index ebb26901e8c..83622b29119 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/27.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/27.json
@@ -1 +1 @@
-{"Abdominal distension ": 3.6878005562341896, "Aneurysm ": 14.896472493686606, "Angina pectoris ": 5.8131658178941805, "Ascites ": 8.199063021325125, "Atelectasis ": 9.607014183201295, "Bladder neoplasm ": 214.99198798090544, "Blood immunoglobulin G increased ": 54.19663242197809, "Blood pressure abnormal ": 4.480595491442218, "Blood pressure decreased ": 3.240378589188541, "Blood pressure diastolic decreased ": 16.461796133706606, "Blood pressure systolic decreased ": 18.167031387000517, "Brain natriuretic peptide increased ": 35.71120497221266, "Bronchiectasis ": 7.228203542577359, "Cachexia ": 14.178485024584898, "Cardiac cirrhosis ": 466.59213295219536, "Cardiac failure ": 5.704150332788748, "Cardiac failure congestive ": 2.2875743704171136, "Cardiomegaly ": 5.1029667003308985, "Catheter site erythema ": 31.09215039085773, "Catheter site infection ": 23.725707624537367, "Catheter site pain ": 58.61882840648245, "Catheter site swelling ": 105.13386574166655, "Central venous catheterisation ": 25.697394403942678, "Cholelithiasis ": 2.6940427654210564, "Colitis ": 2.3153162566123444, "Complication associated with device ": 19.1108755301152, "Concomitant disease aggravated ": 10.458245977333153, "Delirium ": 5.184076086513179, "Device dislocation ": 23.1153981589487, "Device related infection ": 16.910098237378843, "Drug hypersensitivity ": 2.5610156637265917, "Duodenitis ": 24.60719711684903, "Dyspnoea exertional ": 7.401277973368491, "Dysstasia ": 2.4255694829677807, "Eosinophil count increased ": 4.262994294792495, "Eosinophilic oesophagitis ": 54.69795916037025, "Eosinophilic pneumonia ": 10.657785189773763, "Episcleritis ": 63.65494520700914, "Epistaxis ": 2.460733512122954, "Exercise tolerance decreased ": 4.6828264657273495, "Fall ": 2.7224344957079696, "Feeling abnormal ": 2.024008910818581, "Fluid retention ": 10.58654439901657, "Flushing ": 5.008542459656376, "Focal nodular hyperplasia ": 119.50748750356352, "Gamma-glutamyltransferase ": 212.78407609137832, "Gastrointestinal pain ": 4.7052299480691335, "Gastrointestinal wall thickening ": 60.44190481972753, "Haematemesis ": 2.932943338279294, "Haematocrit decreased ": 2.7382750792997625, "Haemoptysis ": 6.78110142447869, "Hepatic cirrhosis ": 7.033824432351459, "Hiccups ": 8.123789971034313, "Hospitalisation ": 6.2916768251943065, "Hot flush ": 2.624695088920644, "Hyperlipidaemia ": 4.939578954714165, "Hyperplasia of thymic epithelium ": 3312.9141942980823, "Hypersplenism ": 136.82930560037616, "Hypervolaemia ": 21.72081284231022, "Hypotension ": 2.422629678754842, "Hypovolaemia ": 10.658654492853346, "Hypoxia ": 6.086202415632863, "Interstitial lung disease ": 2.3807064037286896, "Iron deficiency anaemia ": 11.765056782075728, "Left ventricular failure ": 14.08996904100706, "Lipase increased ": 4.9118258206569845, "Liver disorder ": 3.237375237492586, "Localised infection ": 3.919718180451196, "Mallory-Weiss syndrome ": 62.22821080783974, "Mediastinal disorder ": 206.16236740389, "Mental status changes ": 2.539406521659177, "Nasal congestion ": 4.0079430509532, "Occult blood positive ": 22.21482856195279, "Oedema ": 4.344012397501819, "Oedema peripheral ": 2.731984846024386, "Overlap syndrome ": 169.2042777497253, "Oxygen saturation decreased ": 14.282584438429122, "Pain in jaw ": 22.686402456831495, "Pericardial effusion ": 6.914063135777443, "Peripheral swelling ": 3.807379056808041, "Pharyngeal oedema ": 5.8371633722833005, "Platelet count decreased ": 3.2246804373193183, "Platelet transfusion ": 63.65494520700914, "Pneumonia bacterial ": 9.63258671527971, "Portal fibrosis ": 493.2699308308524, "Portal hypertensive gastropathy ": 190.1001047735297, "Portal tract inflammation ": 435.214280130478, "Pulmonary alveolar haemorrhage ": 7.579080276744194, "Pulmonary arterial hypertension ": 34.03274727586867, "Pulmonary congestion ": 6.701267320435047, "Pulmonary hypertension ": 17.367461238321393, "Pulmonary oedema ": 8.875696350087567, "Renal disorder ": 2.2618408933462346, "Respiratory distress ": 2.0510171629656075, "Respiratory failure ": 2.3920959822605607, "Respiratory syncytial virus infection ": 24.41211866780808, "Retroperitoneal lymphadenopathy ": 103.74743064531977, "Right ventricular failure ": 31.74211611495988, "Scleroderma ": 42.51443995325182, "Serum ferritin decreased ": 30.863988873807475, "Splenomegaly ": 5.445091695802707, "Sputum retention ": 49.06237616204141, "Syncope ": 2.654082870601928, "Systemic scleroderma ": 81.24768652958652, "Transfusion ": 5.3137371965168825, "Troponin increased ": 6.494352890782109, "Varices oesophageal ": 21.885270361976197, "Vascular device infection ": 40.55112942673605}
\ No newline at end of file
+{"Acute myeloid leukaemia": 90.6629433602092, "Anaemia": 2.023261524132719, "Colitis": 7.604807005373669, "Constipation": 3.403794099978616, "Disease progression": 3.0142230171170707, "Enterocolitis": 23.40533475392848, "Febrile neutropenia": 49.705165153382254, "Hodgkin's disease": 304.809430858085, "Hodgkin's disease recurrent": 382.1259086586443, "Intentional product use issue": 3.185199069056277, "Interstitial lung disease": 3.065816015355953, "Leukopenia": 2.2654616869853546, "Malignant neoplasm progression": 2.500141335478064, "Myelosuppression": 5.235131906938769, "Myositis": 32.32992431704492, "Neoplasm progression": 4.999396475545985, "Neuropathy peripheral": 59.3369447767476, "Neutropenia": 16.77712565107658, "Neutrophil count decreased": 29.41691229191931, "Off label use": 3.7397345747944577, "Pancytopenia": 3.3333090118730357, "Peripheral sensory neuropathy": 28.956403504266547, "Pneumocystis jirovecii pneumonia": 36.70440870977886, "Pneumonia": 2.0239026324312097, "Pneumonitis": 6.90516272421026, "Polyneuropathy": 8.777759897138928, "Second primary malignancy": 35.24043607138998, "Sepsis": 5.31194250743399, "Vascular pain": 40.88787656818098, "White blood cell count decreased": 5.397435728311549}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/270.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/270.json
index 674c47f55e8..b9e48ed92ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/270.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/270.json
@@ -1 +1 @@
-{"Abdominal abscess ": 5.403765303250289, "Abdominal adhesions ": 7.966332062231188, "Abdominal operation ": 5.194013025161884, "Abortion ": 2.410748623436002, "Abortion missed ": 2.2379192954486182, "Abortion spontaneous ": 2.6893184239613017, "Abscess ": 5.650877740085182, "Abscess intestinal ": 10.632784878283328, "Adverse drug reaction ": 3.356006351569542, "Adverse event ": 2.404089659482425, "Alopecia ": 2.5768761062588466, "Anal abscess ": 4.856043592079399, "Anal fistula ": 7.458681341348496, "Ankle operation ": 4.935553140089498, "Ankylosing spondylitis ": 77.07517434305815, "Anti-cyclic citrullinated peptide antibody ": 4.464105819633202, "Anti-cyclic citrullinated peptide antibody positive ": 4.017628138355303, "Arthritis ": 2.0671371760664337, "Arthritis bacterial ": 3.516786611990874, "Arthritis infective ": 3.437643931863468, "Arthrodesis ": 14.20421949429828, "Arthropathy ": 4.305032573210535, "Axial spondyloarthritis ": 68.66584521638245, "Back injury ": 2.121292440533906, "Basal cell carcinoma ": 2.1734574986539923, "Blister ": 7.965048363957997, "Blood pressure diastolic abnormal ": 3.4934455283471904, "Blood pressure diastolic increased ": 2.2017891762489423, "Bone erosion ": 2.39266632837647, "Breech presentation ": 6.121922775596226, "Bronchitis ": 2.4855468498444586, "Butterfly rash ": 4.213728663047349, "C-reactive protein abnormal ": 4.372986392654715, "C-reactive protein decreased ": 6.778591043839805, "Caesarean section ": 9.275905535585336, "Carpal tunnel syndrome ": 2.580782422396769, "Cellulitis ": 2.0991154964834227, "Clostridium difficile infection ": 3.002585580195356, "Coeliac disease ": 2.611479313126323, "Colectomy ": 3.3412561377999723, "Colitis microscopic ": 2.4391187651229056, "Colostomy ": 7.060240194721985, "Confusional state ": 2.7868644743756663, "Contraindicated product administered ": 9.139654051733412, "Contraindication to medical treatment ": 8.904888839553843, "Contusion ": 3.856073233314604, "Crohn's disease ": 27.157010758511703, "Croup infectious ": 8.167740694539107, "Cutaneous T-cell lymphoma ": 4.556434720007007, "Dactylitis ": 4.664513403590672, "Demyelinating polyneuropathy ": 2.549368610741219, "Demyelination ": 2.281851597732297, "Dermatitis psoriasiform ": 5.9649045740410855, "Device issue ": 6.348631306612947, "Diabetic eye disease ": 10.137098243849817, "Disseminated tuberculosis ": 6.945541698596145, "Diverticular perforation ": 4.433828401628127, "Drug hypersensitivity ": 2.966083482676343, "Drug ineffective ": 4.323004262379306, "Drug intolerance ": 5.01332174475362, "Drug specific antibody present ": 5.190419002760764, "Duodenal ulcer perforation ": 4.919933726969172, "Ear infection ": 2.275784953666424, "Ear pain ": 3.5548786332912696, "Enteritis infectious ": 3.17329169488174, "Enthesopathy ": 4.328978148542721, "Exposure to SARS-CoV-2 ": 6.634374531411826, "Exposure via breast milk ": 5.601344619762495, "Eye infection ": 2.0051793342526394, "Facet joint syndrome ": 3.2547225752119027, "Fear of injection ": 4.089456804164127, "Fibromyalgia ": 2.2966668644952866, "Fine motor skill dysfunction ": 4.2250061033487, "Fistula ": 13.356956916665265, "Folliculitis ": 30.64772172568333, "Foot operation ": 3.3507898573249024, "Fungal infection ": 3.254772315692148, "Gallbladder operation ": 2.899607146638193, "Gastric infection ": 3.1284584018076647, "Gastroenteritis viral ": 2.378696337916613, "Gastrointestinal disorder ": 8.255972126511143, "Gastrointestinal infection ": 2.041999074780153, "Gastrointestinal inflammation ": 2.249389789070774, "Gestational diabetes ": 5.495812119432511, "Gestational hypertension ": 2.654718599477569, "Glossodynia ": 3.538847448953307, "Grip strength decreased ": 5.76231782224933, "Groin abscess ": 5.151651163105396, "Guttate psoriasis ": 3.6914724927390754, "Hand deformity ": 4.25835228837303, "Helicobacter infection ": 4.9750139638081565, "Hepatic enzyme increased ": 2.1675295215674093, "Hernia ": 2.609094590820507, "Hernia repair ": 3.8876252647257368, "Hidradenitis ": 9.4000427911574, "Hip arthroplasty ": 3.717593617854537, "Hip surgery ": 3.1395880281686988, "Hospitalisation ": 2.871525901494822, "Hypersensitivity ": 4.424120274967708, "Hysterectomy ": 2.631512360634101, "Ileal stenosis ": 11.303376972032016, "Ileostomy ": 10.683392951223796, "Ill-defined disorder ": 15.222508493103383, "Immunosuppression ": 3.0287213766976744, "Impaired healing ": 23.846800106694268, "Inability to afford medication ": 10.5101716106299, "Infection ": 8.48455375233668, "Inflammation ": 2.285354297074665, "Inflammatory bowel disease ": 3.712675855536364, "Inflammatory marker increased ": 4.701261183651728, "Infusion related reaction ": 2.386729055641581, "Injection site bruising ": 2.539293763525705, "Injection site discolouration ": 17.048523272022646, "Injection site haemorrhage ": 2.11013919827168, "Injection site irritation ": 3.786251237328044, "Injection site rash ": 2.6908221422303, "Injection site urticaria ": 3.251129943625961, "Injection site vesicles ": 2.1429518965813568, "Insurance issue ": 41.84917315920302, "Intentional dose omission ": 12.84291335166854, "Intentional product use issue ": 2.0783979748450414, "Intercepted product prescribing error ": 6.133378396493077, "Intervertebral discitis ": 2.368664413605335, "Intestinal obstruction ": 3.227984517342913, "Intestinal resection ": 15.434734262646735, "Intestinal stenosis ": 19.61296177341615, "Intestinal ulcer ": 3.956202933851017, "Intra-abdominal fluid collection ": 2.8247976204507483, "Iron deficiency anaemia ": 2.182474194863138, "Irritable bowel syndrome ": 29.22903886591617, "Joint arthroplasty ": 10.13906413396668, "Joint effusion ": 3.5393969472565843, "Joint injury ": 2.687809998281132, "Joint lock ": 2.5450388060309463, "Joint stiffness ": 2.823734743517155, "Joint swelling ": 10.015853476221784, "Joint warmth ": 2.2675807696834, "Juvenile idiopathic arthritis ": 11.807830585579676, "Kidney infection ": 2.5763847489257863, "Knee arthroplasty ": 4.018604794216641, "Knee operation ": 4.767332042148009, "Large intestinal stenosis ": 11.227975899318842, "Latent tuberculosis ": 9.26262196935666, "Ligament rupture ": 5.20665111649671, "Limb operation ": 2.737561857072276, "Lip ulceration ": 10.041032503182407, "Liver function test increased ": 2.989521300876958, "Loss of personal independence in daily activities ": 3.032854617310936, "Loss of therapeutic response ": 3.099942773167552, "Low birth weight baby ": 5.001820523592239, "Lower respiratory tract infection ": 20.26161822074207, "Lung adenocarcinoma ": 2.7856866297565377, "Lupus-like syndrome ": 9.2787729478573, "Lymph node tuberculosis ": 7.379343097928687, "Lymphoproliferative disorder ": 3.46824380424903, "Maternal exposure before pregnancy ": 55.73641010039992, "Maternal exposure during breast feeding ": 13.108665570439214, "Maternal exposure during pregnancy ": 8.501416567092992, "Meningitis ": 2.308196561470091, "Menopause ": 6.383010905401272, "Mouth ulceration ": 2.040270593375836, "Muscle injury ": 53.28368191580831, "Muscle spasticity ": 3.2656670557140512, "Mycobacterium tuberculosis complex test positive ": 13.202259101927009, "Nail disorder ": 7.334374446264041, "Nail operation ": 20.74366818411284, "Nail psoriasis ": 12.58621256834057, "Nasopharyngitis ": 6.924987708275627, "Neck mass ": 2.8649195576462816, "Neck surgery ": 5.018470107156419, "Needle issue ": 5.281202013630307, "Non-alcoholic fatty liver ": 8.973140985549891, "Onychomadesis ": 7.63890452214577, "Onychomycosis ": 12.499882906579542, "Optic neuritis ": 2.067653581497214, "Oral infection ": 4.213934720723039, "Ovarian disorder ": 11.159622841328934, "Palmoplantar pustulosis ": 17.161376005049508, "Papilloma viral infection ": 2.1577202957596198, "Paradoxical psoriasis ": 26.15502052521021, "Pemphigus ": 3.6586710550476425, "Peripheral swelling ": 4.44986124933645, "Peripheral venous disease ": 2.908719501866156, "Perirectal abscess ": 10.018949033417709, "Peritoneal tuberculosis ": 13.94469109812356, "Pertussis ": 5.7391930925206855, "Pharyngitis streptococcal ": 5.9039332459305065, "Pneumonia legionella ": 6.976463880571726, "Polyarthritis ": 2.578406131922832, "Post procedural infection ": 2.994667647337176, "Pregnancy ": 2.262536937481636, "Pregnancy on contraceptive ": 4.9574817533598505, "Premature baby ": 2.2504761444678416, "Premature delivery ": 4.610093554704861, "Premature rupture of membranes ": 2.7935991501198085, "Procedural pain ": 2.865014836702534, "Proctalgia ": 2.4567204029914484, "Product availability issue ": 8.024197737829825, "Product distribution issue ": 13.240319325083757, "Product dose omission in error ": 2.857514498487939, "Product dose omission issue ": 3.365618526074924, "Psoriasis ": 10.59522853520784, "Psoriatic arthropathy ": 15.422106312276972, "Pulmonary sarcoidosis ": 4.117240292312848, "Pulmonary tuberculosis ": 3.239577667191264, "Pustular psoriasis ": 6.639393706416398, "Quality of life decreased ": 2.4716785346551564, "Rectal abscess ": 18.384914281204043, "Red blood cell sedimentation rate abnormal ": 5.548832658261476, "Rheumatic fever ": 12.880976966082926, "Rheumatoid arthritis ": 19.28403753308313, "Rheumatoid factor negative ": 32.11747857238719, "Rheumatoid factor positive ": 3.0033879385232582, "SARS-CoV-2 test negative ": 5.488150365774672, "Sacroiliitis ": 7.847750960247351, "Sarcoidosis ": 2.447485610845775, "Serum sickness ": 4.068640380530852, "Shoulder arthroplasty ": 2.951268166059623, "Shoulder operation ": 3.1327384456900718, "Sinus disorder ": 2.307452977914312, "Sinusitis ": 15.466137674384894, "Sjogren's syndrome ": 2.0358165845386416, "Skin cancer ": 2.6504238543620406, "Skin infection ": 2.173299914758889, "Sleep disorder ": 2.797161979512248, "Sleep disorder due to general medical condition, insomnia type ": 46.33495291967442, "Small for dates baby ": 3.0175842901332124, "Small intestinal obstruction ": 5.139344961903111, "Spinal fusion surgery ": 2.447243175760893, "Spinal operation ": 3.3136999440473653, "Spinal stenosis ": 4.36921179170128, "Spondylitis ": 2.085194695992464, "Staphylococcal infection ": 2.5447318845239675, "Stomatitis ": 9.703749423925144, "Streptococcal infection ": 2.172062824306629, "Stress ": 2.6307595387224576, "Stress fracture ": 6.888361547584975, "Subcutaneous abscess ": 4.195888796306615, "Surgery ": 10.577358921951962, "Swelling ": 5.527716011154509, "Swollen joint count increased ": 5.767018948790028, "Synovitis ": 13.66204840752829, "Syringe issue ": 4.412264864128447, "Systemic lupus erythematosus ": 3.454064013744959, "Tendon pain ": 3.0778554884587708, "Therapeutic product effect decreased ": 19.04006000025908, "Therapeutic response shortened ": 13.943648782602017, "Therapy cessation ": 2.5274050588327457, "Therapy interrupted ": 28.252553189264148, "Tooth abscess ": 2.5644337830174586, "Tooth infection ": 2.502074311756609, "Transaminases abnormal ": 6.795047946597921, "Treatment failure ": 5.491201583971994, "Tuberculin test positive ": 16.84121031811707, "Tuberculosis ": 6.662518110693955, "Twin pregnancy ": 17.944659623278998, "Type 2 diabetes mellitus ": 2.7173077331078144, "Upper respiratory tract infection ": 2.692425945512653, "Urinary tract infection ": 2.708509494914809, "Uveitis ": 8.993196914260153, "Weight increased ": 4.488746646846282, "Wheelchair user ": 2.246067767444204, "X-ray abnormal ": 20.774200872363217}
\ No newline at end of file
+{"Cellulitis": 159.32369994182676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/271.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/271.json
index bccd6286fd6..1fb15de516b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/271.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/271.json
@@ -1 +1 @@
-{"Blood parathyroid hormone increased ": 103.91006500180652, "Calciphylaxis ": 300.190411977793, "Cholelithiasis ": 8.787950398606334, "Death ": 13.156405955651817, "Diarrhoea ": 2.113753331138804, "Disease progression ": 2.54674751617962, "Drug ineffective ": 2.1013344625657924, "Exposure during pregnancy ": 2.477879859003009, "Foetal exposure during pregnancy ": 9.842911919899434, "Gastrointestinal disorder ": 4.766259927610637, "Hypercalcaemia ": 74.16233246502723, "Hypocalcaemia ": 116.03859378297116, "Hypomagnesaemia ": 29.49062506154964, "Low birth weight baby ": 32.968006986081015, "Maternal exposure during pregnancy ": 6.86188301810864, "Normal newborn ": 46.40508512384153, "Premature baby ": 26.46755019392775, "Premature delivery ": 20.12054408455916, "Rash pruritic ": 3.009111845856291, "Rectal haemorrhage ": 4.418707178753816, "Sepsis ": 3.071000454438414, "Urinary tract infection ": 2.260921714591871, "Vomiting ": 2.500601527984508}
\ No newline at end of file
+{"Blister": 44.187351627185386, "Drug eruption": 95.08060263820587, "Erythema": 12.910281109142842, "Erythema multiforme": 133.40075345068618, "Lymphocytic infiltration": 2494.937340658309, "Mucosal erosion": 2307.4006469383025, "Multiple organ dysfunction syndrome": 88.44252085104105, "Sepsis": 41.55283791329928, "Staphylococcal infection": 177.1807280797498, "Staphylococcal scalded skin syndrome": 13749.967313847352, "Toxic epidermal necrolysis": 142.10352587642558, "Uterine haemorrhage": 640.7550590872742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/272.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/272.json
index a5360423833..d8a73bb4155 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/272.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/272.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 4.352654143550742, "Angioedema ": 7.445373446651264, "Complication associated with device ": 38.655144476502414, "Device related infection ": 19.926846416457927, "Exposure during pregnancy ": 7.8920769342315396, "Hereditary angioedema ": 786.3584686317851, "Hospitalisation ": 9.845387999048516, "Inappropriate schedule of product administration ": 26.81581071894328, "Incorrect drug administration rate ": 62.40536052352757, "Infusion related reaction ": 9.204765678981673, "Laryngeal oedema ": 13.42755452938998, "Off label use ": 2.2990442975144783, "Poor venous access ": 172.09378108364504, "Prescribed overdose ": 24.101428144326384, "Product dose omission issue ": 8.953254952537142, "Product use in unapproved indication ": 5.038553440713878, "Sepsis ": 2.13093587934743, "Sinusitis ": 2.282089771147339, "Staphylococcal infection ": 6.843836990133736, "Stress ": 6.568027563436781, "Therapeutic product effect decreased ": 3.2720390997967184, "Therapy change ": 677.5994164670113, "Thrombosis ": 2.483107490169305, "Unevaluable event ": 6.106478130705123, "Vascular device infection ": 155.2045432124882}
\ No newline at end of file
+{"Abdominal lymphadenopathy": 8.680605595868215, "Abdominal mass": 5.345096473876784, "Abdominal tenderness": 3.190673429927936, "Abscess": 2.643891075001656, "Abscess drainage": 11.712332878803538, "Acanthosis": 17.34342310253314, "Acid fast bacilli infection": 34.137733172709574, "Acinetobacter infection": 17.025623278808453, "Actinic keratosis": 6.873740191550037, "Acute graft versus host disease": 105.14005965496918, "Acute graft versus host disease in intestine": 107.1599394000188, "Acute graft versus host disease in liver": 100.64234815671664, "Acute graft versus host disease in skin": 104.12848710121092, "Acute leukaemia": 2.139587034053692, "Acute lymphocytic leukaemia": 2.969409308678652, "Acute lymphocytic leukaemia recurrent": 12.218235916316235, "Acute myeloid leukaemia": 4.444251429714038, "Acute myeloid leukaemia recurrent": 21.351144153470777, "Acute respiratory distress syndrome": 2.625351660784183, "Adenoviral haemorrhagic cystitis": 54.9906257986634, "Adenoviral 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9.3962106401663, "Venoocclusive disease": 10.348914914976222, "Venoocclusive liver disease": 5.518403766586602, "Viraemia": 4.520490753117547, "Viral haemorrhagic cystitis": 51.04483396474568, "Viral infection": 3.10694214455313, "Viral test positive": 38.20956384999442, "Visceral leishmaniasis": 35.791905699531085, "West Nile viral infection": 40.37727160752375, "Wound dehiscence": 3.417448058942931}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/273.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/273.json
index 3556e2873ef..9ce80f2eb5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/273.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/273.json
@@ -1 +1 @@
-{"Abnormal dreams ": 11.465604490786784, "Aggression ": 5.947004397993815, "Agitation ": 7.1478951115526215, "Agranulocytosis ": 4.245743534894539, "Akathisia ": 9.333845112202145, "Confusional state ": 2.739433826776972, "Depressed mood ": 2.291865086084391, "Disorientation ": 3.2616248585858125, "Disturbance in attention ": 2.272031838453262, "Dry mouth ": 2.585894674187002, "Epilepsy ": 3.9065289112923858, "Flatulence ": 4.70707468977219, "Hallucination ": 2.4172366783909487, "Hepatic cytolysis ": 4.117291280695244, "Hyperthyroidism ": 3.9692516583275887, "Hyponatraemia ": 2.610295710324878, "Incorrect product administration duration ": 7.978143020267403, "Initial insomnia ": 12.786826748189362, "Insomnia ": 3.0486810359517484, "Intentional overdose ": 12.446035773319412, "Intentional self-injury ": 30.720896867071737, "Irritability ": 3.2313247085520844, "Labelled drug-drug interaction medication error ": 14.852121223881658, "Middle insomnia ": 21.07027534721172, "Mixed liver injury ": 34.87244284217698, "Nervousness ": 2.648308451035515, "Night sweats ": 3.661918913374096, "Nightmare ": 16.279928442093993, "Nocturia ": 11.33478305423614, "Off label use ": 2.350284432991073, "Overdose ": 4.953701314060728, "Palpitations ": 2.4883188312117897, "Poor quality sleep ": 10.39316768658454, "Prescribed overdose ": 11.727236751747808, "Product administered to patient of inappropriate age ": 237.60224187662067, "Product use issue ": 3.6287814862931618, "Purpura ": 10.53706242415973, "Rash macular ": 3.895195151923355, "Rash maculo-papular ": 5.624580362637078, "Restless legs syndrome ": 10.03443665016759, "Restlessness ": 8.214943239839949, "Sedation ": 5.800682164551576, "Sleep disorder ": 3.328391424298381, "Somnolence ": 7.877651380703721, "Suicide attempt ": 4.480373400572181, "Vision blurred ": 2.474553016854664, "Wrong technique in product usage process ": 4.568922209900865}
\ No newline at end of file
+{"Acute kidney injury": 5.785850433581323, "Adenovirus infection": 178.91709454538486, "Blood creatinine increased": 5.193897657878051, "Cytomegalovirus colitis": 162.29863038383192, "Cytomegalovirus infection": 41.440928314154455, "Cytomegalovirus infection reactivation": 66.90277757766741, "Disease progression": 2.623364475754772, "Drug ineffective": 4.648208099743908, "Drug ineffective for unapproved indication": 66.20740585584294, "Drug resistance": 66.19412812334754, "Graft versus host disease in gastrointestinal tract": 145.9283893197127, "Haematuria": 4.976482507869688, "Hemiparesis": 11.185868631595154, "Multiple-drug resistance": 60.847392246304615, "Myelosuppression": 4.7153669730625785, "Nephropathy toxic": 105.4011116265018, "Neutropenia": 2.1391713716758174, "Off label use": 8.17488774994098, "Pancytopenia": 8.245672673576786, "Pathogen resistance": 29.723942328537767, "Polyomavirus-associated nephropathy": 175.93598661295954, "Product use in unapproved indication": 4.559701506585711, "Product use issue": 7.898429186621002, "Progressive multifocal leukoencephalopathy": 88.93765803221706, "Renal failure": 2.290129625039424, "Renal impairment": 14.528366705436037, "Respiratory failure": 7.2026435272167815, "Uveitis": 50.39468728080397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/274.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/274.json
index 049eb06f11e..f12bd3f7c3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/274.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/274.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 27.049446793580245, "Acute myeloid leukaemia recurrent ": 44.58264613234225, "Agranulocytosis ": 2.2373629814570224, "Anaemia ": 3.190123008504732, "Aspergillus infection ": 23.802717880151977, "Bronchopulmonary aspergillosis ": 25.96114587225858, "Clostridium bacteraemia ": 1957.8827723725296, "Clostridium difficile infection ": 6.070420664000085, "Cytopenia ": 6.426857346856362, "Demodicidosis ": 2700.08201525175, "Disease progression ": 3.2888622444537363, "Disease recurrence ": 6.596649099617163, "Enterococcal infection ": 53.53836207405568, "Febrile neutropenia ": 22.688508091551977, "Haematotoxicity ": 13.235147303194593, "Hairy cell leukaemia ": 1196.8137419501625, "Hairy cell leukaemia recurrent ": 4039.7874875360335, "Hyperbilirubinaemia ": 5.348457993814543, "Hypoalbuminaemia ": 16.954039956950083, "Incorrect dose administered ": 3.8544604396674607, "Infection ": 2.479593854866181, "Langerhans' cell histiocytosis ": 354.6834325581087, "Leukopenia ": 4.44222378542556, "Lymphocyte count decreased ": 27.903304097236344, "Lymphopenia ": 68.82968895258274, "Multiple organ dysfunction syndrome ": 6.7989066677518455, "Multiple sclerosis ": 8.726772442789567, "Multiple sclerosis relapse ": 15.519533093867665, "Myelodysplastic syndrome ": 62.9200925648239, "Myelosuppression ": 6.658471251034292, "Neoplasm progression ": 2.043606209396206, "Neutropenia ": 8.580285828909735, "Neutropenic colitis ": 98.72312854272454, "Neutrophil count decreased ": 2.69237081794614, "Off label use ": 4.640900072651839, "Pancytopenia ": 38.17989303271306, "Pneumonia ": 2.0953979966261205, "Product use in unapproved indication ": 12.26969091218833, "Rash maculo-papular ": 8.128794293862292, "Respiratory failure ": 3.9887900386548223, "Sepsis ": 6.033897755790791, "Septic shock ": 3.044982004551825, "Therapeutic product effect incomplete ": 3.4530407261775795, "Thrombocytopenia ": 6.136233854978364, "Toxic skin eruption ": 4.775728324497839, "White blood cell count decreased ": 2.105249887368532}
\ No newline at end of file
+{"Abdominal abscess": 5.403095107001551, "Abdominal adhesions": 7.965344055111967, "Abdominal operation": 5.193368855168888, "Abortion": 2.4104496336379198, "Abortion missed": 2.237641744302947, "Abortion spontaneous": 2.6889848605295485, "Abscess": 5.650176867335564, "Abscess intestinal": 10.63146616944403, "Adverse drug reaction": 3.355590098400398, "Adverse event": 2.4037914747227824, "Alopecia": 2.576556454899124, "Anal abscess": 4.855441324347547, "Anal fistula": 7.457756284708322, "Ankle operation": 4.934941025448542, "Ankylosing spondylitis": 77.0656137026122, "Anti-cyclic citrullinated peptide antibody": 4.463552164771494, "Anti-cyclic citrullinated peptide antibody positive": 4.017129818210734, "Arthritis": 2.0668807812810552, "Arthritis bacterial": 3.5163504461458084, "Arthritis infective": 3.4372175831677723, "Arthrodesis": 14.202457832095291, "Arthropathy": 4.304498566760303, "Axial spondyloarthritis": 68.6573289879897, "Back injury": 2.1210293469977315, "Basal cell carcinoma": 2.173187934419552, "Blister": 7.964060284421388, "Blood pressure diastolic abnormal": 3.4930122630741085, "Blood pressure diastolic increased": 2.2015161041394777, "Bone erosion": 2.3923695795306616, "Breech presentation": 6.121163519938034, "Bronchitis": 2.485087725210056, "Butterfly rash": 4.213206068264923, "C-reactive protein abnormal": 4.372444007424441, "C-reactive protein decreased": 6.777750347482879, "Caesarean section": 9.274755043025657, "Carpal tunnel syndrome": 2.580462338797691, "Cellulitis": 2.0988551404226183, "Clostridium difficile infection": 3.002213175735472, "Coeliac disease": 2.611155419131056, "Colectomy": 3.3408417447739844, "Colitis microscopic": 2.438816257706198, "Colostomy": 7.05936456594162, "Confusional state": 2.7865187634270883, "Contraindicated product administered": 9.138520266724, "Contraindication to medical treatment": 8.903784433049616, "Contusion": 3.855594909891202, "Crohn's disease": 27.1536418603596, "Croup infectious": 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3.264402615606399, "Mycobacterium tuberculosis complex test positive": 13.200621705389882, "Nail disorder": 7.333464786126508, "Nail operation": 20.74109551889321, "Nail psoriasis": 12.584651601708872, "Nasopharyngitis": 6.923583146695927, "Neck mass": 2.864564243255378, "Neck surgery": 5.017847706167466, "Needle issue": 5.280546999076598, "Non-alcoholic fatty liver": 8.972028118650744, "Onychomadesis": 7.6379571048673345, "Onychomycosis": 12.498332587118398, "Optic neuritis": 2.067397141142286, "Oral infection": 4.2134120977346186, "Ovarian disorder": 11.15823879620858, "Palmoplantar pustulosis": 17.15924758291604, "Papilloma viral infection": 2.157452691048843, "Paradoxical psoriasis": 26.15177672994138, "Pemphigus": 3.6582172553097054, "Peripheral swelling": 4.449309221869319, "Peripheral venous disease": 2.9083587511426905, "Perirectal abscess": 10.017706463459527, "Peritoneal tuberculosis": 13.942961654350846, "Pertussis": 5.73848130530222, "Pharyngitis streptococcal": 5.90320101543447, "Pneumonia legionella": 6.975598641932013, "Polyarthritis": 2.578086345802173, "Post procedural infection": 2.9942962386763763, "Pregnancy": 2.262256325760531, "Pregnancy on contraceptive": 4.956866919101139, "Premature baby": 2.250197016815483, "Premature delivery": 4.609521765008836, "Premature rupture of membranes": 2.793252679788289, "Procedural pain": 2.864659499329008, "Proctalgia": 2.45641571138052, "Product availability issue": 8.023202489502967, "Product distribution issue": 13.238677210405918, "Product dose omission in error": 2.857160096491197, "Product dose omission issue": 3.3652010372497294, "Psoriasis": 10.59391422304764, "Psoriatic arthropathy": 15.42019328432184, "Pulmonary sarcoidosis": 4.116729663645673, "Pulmonary tuberculosis": 3.239175881053755, "Pustular psoriasis": 6.989717702918098, "Quality of life decreased": 2.4713719824224247, "Rectal abscess": 18.38263412236862, "Red blood cell sedimentation rate abnormal": 5.548144461721787, "Rheumatic fever": 12.879379333162904, "Rheumatoid arthritis": 19.281644836320517, "Rheumatoid factor negative": 32.11349524032114, "Rheumatoid factor positive": 3.0030154392470445, "SARS-CoV-2 test negative": 5.4874697067785005, "Sacroiliitis": 7.846777653004459, "Sarcoidosis": 2.447182062679177, "Serum sickness": 4.068135772721926, "Shoulder arthroplasty": 2.950902143619341, "Shoulder operation": 3.1323499161345327, "Sinus disorder": 2.3071667970336445, "Sinusitis": 15.464219053512572, "Sjogren's syndrome": 2.035564095747854, "Skin cancer": 2.6500951334330227, "Skin infection": 2.173030373607651, "Sleep disorder": 2.796815022532786, "Sleep disorder due to general medical condition, insomnia type": 46.3292055953065, "Small for dates baby": 3.017210040199233, "Small intestinal obstruction": 5.138707548865349, "Spinal fusion surgery": 2.446939663534019, "Spinal operation": 3.3132889614062018, "Spinal stenosis": 4.368669896329724, "Spondylitis": 2.0849360857654826, "Staphylococcal infection": 2.5444162646675825, "Stomatitis": 9.702545674113416, "Streptococcal infection": 2.171793439958505, "Stress": 2.630433241704332, "Stress fracture": 6.887507223734114, "Subcutaneous abscess": 4.195368405201179, "Surgery": 10.576046923724103, "Swelling": 5.527030278815883, "Swollen joint count increased": 5.766303692818595, "Synovitis": 13.660353744180268, "Syringe issue": 4.411717638769053, "Systemic lupus erythematosus": 3.4536355867660995, "Tendon pain": 3.077473754607861, "Therapeutic product effect decreased": 19.037697971868138, "Therapeutic response shortened": 13.941919370930329, "Therapy cessation": 2.527091598103696, "Therapy interrupted": 28.24904881919503, "Tooth abscess": 2.564115732163432, "Tooth infection": 2.5017639942967804, "Transaminases abnormal": 6.794205207600851, "Treatment failure": 5.490520437117287, "Tuberculin test positive": 16.8391215949838, "Tuberculosis": 6.661691757930691, "Twin pregnancy": 17.94243406781907, "Type 2 diabetes mellitus": 2.716970707274378, "Upper respiratory tract infection": 2.6920920034254463, "Urinary tract infection": 2.7081735311241197, "Uveitis": 8.99208146113299, "Weight increased": 4.488189811476729, "Wheelchair user": 2.2457892042912224, "X-ray abnormal": 20.77162435893641}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/275.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/275.json
index 9e17667a4c1..72a487925df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/275.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/275.json
@@ -1 +1 @@
-{"Disease recurrence ": 25.15581425248938, "Drug hypersensitivity ": 18.63975385307859, "Drug ineffective ": 2.239465354046361, "Joint range of motion decreased ": 43.28735853395841, "Lyme disease ": 251.9226149215846, "Pneumonia ": 6.813956239750337}
\ No newline at end of file
+{"Blood parathyroid hormone increased": 103.91006500180652, "Calciphylaxis": 300.190411977793, "Cholelithiasis": 8.787950398606334, "Death": 13.156405955651817, "Diarrhoea": 2.113735689904808, "Disease progression": 2.54674751617962, "Drug ineffective": 2.10131892803171, "Exposure during pregnancy": 2.477879859003009, "Foetal exposure during pregnancy": 9.842911919899434, "Gastrointestinal disorder": 4.766109842559024, "Hypercalcaemia": 74.16233246502723, "Hypocalcaemia": 116.03859378297116, "Hypomagnesaemia": 29.49062506154964, "Low birth weight baby": 32.968006986081015, "Maternal exposure during pregnancy": 6.86188301810864, "Normal newborn": 46.40508512384153, "Premature baby": 26.46755019392775, "Premature delivery": 20.12054408455916, "Rash pruritic": 3.009111845856291, "Rectal haemorrhage": 4.418707178753816, "Sepsis": 3.071000454438414, "Urinary tract infection": 2.260921714591871, "Vomiting": 2.5005677924651333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/276.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/276.json
index 8bfbd001281..7d4277f4e04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/276.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/276.json
@@ -1 +1 @@
-{"Acute lymphocytic leukaemia ": 81.50811653228288, "Acute myeloid leukaemia ": 31.76048968967356, "Acute myeloid leukaemia recurrent ": 66.45208138161259, "Anaemia ": 2.7672194994595105, "Aspergillus infection ": 31.13863881843494, "Bone marrow failure ": 45.64731766443301, "Capillary leak syndrome ": 113.56356207144614, "Cellulitis ": 7.785494328399304, "Colitis ": 5.1551841796299085, "Disease progression ": 6.142890052573388, "Drug resistance ": 5.220164781447125, "Febrile neutropenia ": 21.71906540082924, "Fusarium infection ": 322.4011120110772, "Hepatotoxicity ": 7.595775336717903, "Hyperbilirubinaemia ": 12.53120197398825, "Infection ": 3.0705472904990945, "Klebsiella sepsis ": 136.05771328017923, "Leukaemia recurrent ": 77.08779789168332, "Lymphopenia ": 23.736809040512, "Malignant neoplasm progression ": 2.6297882588930475, "Mucosal inflammation ": 10.625306983762046, "Multiple organ dysfunction syndrome ": 18.03431775606538, "Neoplasm progression ": 3.410873043513219, "Neutropenia ": 6.956907427150775, "Off label use ": 2.5813209870849096, "Palmar-plantar erythrodysaesthesia syndrome ": 9.674008355036984, "Pancytopenia ": 8.462996114289497, "Pneumonia ": 2.3814190786406546, "Product use in unapproved indication ": 2.016291808389141, "Product use issue ": 4.355088636534059, "Pulmonary mass ": 15.478337669749374, "Rash maculo-papular ": 3.293765757246716, "Respiratory failure ": 5.014984057171459, "Sepsis ": 7.408162315464749, "Septic shock ": 12.769989342297688, "Sinusitis ": 5.567235863554169, "Stomatitis ": 2.4413089805958617, "Swelling face ": 2.897593172655154, "Therapy non-responder ": 9.934147011283091, "Thrombocytopenia ": 4.07010763867743, "Transaminases increased ": 3.7368416377832654}
\ No newline at end of file
+{"Abortion spontaneous": 4.352654143550742, "Angioedema": 7.445373446651264, "Complication associated with device": 38.655144476502414, "Device related infection": 19.926846416457927, "Exposure during pregnancy": 7.8920769342315396, "Hereditary angioedema": 786.3584686317851, "Hospitalisation": 9.845387999048516, "Inappropriate schedule of product administration": 26.81581071894328, "Incorrect drug administration rate": 62.40536052352757, "Infusion related reaction": 9.204765678981673, "Laryngeal oedema": 13.42755452938998, "Off label use": 2.298953726511303, "Poor venous access": 172.09378108364504, "Prescribed overdose": 24.101428144326384, "Product dose omission issue": 8.953254952537142, "Product use in unapproved indication": 5.038396230068543, "Sepsis": 2.13093587934743, "Sinusitis": 2.282089771147339, "Staphylococcal infection": 6.843836990133736, "Stress": 6.568027563436781, "Therapeutic product effect decreased": 3.2720390997967184, "Therapy change": 677.5994164670113, "Thrombosis": 2.483107490169305, "Unevaluable event": 6.106478130705123, "Vascular device infection": 155.2045432124882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/277.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/277.json
index 6d38d4eaf67..8c30286b253 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/277.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/277.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.158310917430628, "Abdominal pain upper ": 2.075140331279083, "Abdominal tenderness ": 5.140017334644753, "Abdominal wall haematoma ": 10.114151823966848, "Acquired haemophilia ": 9.340626889969094, "Activated partial thromboplastin time prolonged ": 3.4532026165654037, "Acute coronary syndrome ": 4.998620401909475, "Acute myocardial infarction ": 7.865502278055255, "Akinesia ": 2.2360412093580933, "Allergic cough ": 14.725311616352537, "Amaurosis ": 15.19109012098996, "Anaemia ": 2.735770622474474, "Anaemia macrocytic ": 2.3477833114373263, "Anal haemorrhage ": 3.8157259600014415, "Angina pectoris ": 3.493836686260948, "Angina unstable ": 4.950995703904378, "Angiodysplasia ": 12.688749454675072, "Angiopathy ": 2.545312035007541, "Angioplasty ": 4.130656930717373, "Anticoagulation drug level above therapeutic ": 2.086849182284414, "Aortic aneurysm ": 2.3641183508725288, "Aortic arteriosclerosis ": 2.5021840563469584, "Aortic stenosis ": 3.0412668697915946, "Aortic thrombosis ": 6.214309686572341, "Aortic valve incompetence ": 3.819298092502562, "Aortic valve stenosis ": 4.821591301420276, "Aphasia ": 2.054712868220362, "Arterial haemorrhage ": 20.6059909811743, "Arterial injury ": 9.55799862144343, "Arterial rupture ": 10.211024499536814, "Arterial thrombosis ": 3.006575658523409, "Arteriosclerosis coronary artery ": 2.121391044178571, "Atheroembolism ": 38.85042299652065, "Atrial thrombosis ": 3.0775439563132663, "Basal ganglia haemorrhage ": 7.166514415946006, "Behaviour disorder ": 2.3996863199813623, "Bladder disorder ": 2.5365319088348848, "Bleeding time prolonged ": 12.397029740644603, "Bleeding varicose vein ": 7.974073917778734, "Blood albumin decreased ": 2.1995736055801647, "Blood aldosterone decreased ": 54.23659967521549, "Blood cholesterol ": 35.45634961220281, "Blood fibrinogen increased ": 3.199922434612168, "Blood iron decreased ": 3.9772751489881975, "Blood loss anaemia ": 42.42772001214277, "Blood osmolarity increased ": 16.92456982373375, "Blood pressure diastolic decreased ": 5.759557969354538, "Blood pressure systolic abnormal ": 7.441582571895414, "Blood pressure systolic decreased ": 2.1612754406515995, "Body mass index decreased ": 10.420439882071758, "Brain herniation ": 10.450232712137264, "Brain stem haemorrhage ": 15.619204457777888, "Bronchitis ": 2.985298901728321, "Bundle branch block left ": 2.7020030384458047, "Cardiac aneurysm ": 15.28714788047587, "Cardiac death ": 6.36854906882229, "Cardiac failure acute ": 3.048286172336096, "Cardiac failure chronic ": 3.482872869720398, "Cardiac fibrillation ": 2.555329929368152, "Cardiac tamponade ": 9.51010582894025, "Cardiac ventricular thrombosis ": 6.594604258241137, "Cardiogenic shock ": 2.3335780219453928, "Carotid arteriosclerosis ": 5.114031608264401, "Carotid artery occlusion ": 2.514811233509634, "Carotid artery stenosis ": 3.115325471763392, "Catheter site haematoma ": 27.212191085595364, "Catheter site haemorrhage ": 6.992388416708983, "Cerebellar haematoma ": 8.903028453938528, "Cerebellar haemorrhage ": 14.629560660219465, "Cerebral artery embolism ": 5.47832433615844, "Cerebral haematoma ": 15.9748591714302, "Cerebral haemorrhage ": 8.637510762302227, "Cerebral infarction ": 3.183037869673301, "Cerebral mass effect ": 12.72186839647132, "Cerebral microhaemorrhage ": 12.5934869229776, "Cholecystitis acute ": 2.097446672951597, "Chronic gastritis ": 17.04574887142867, "Coagulation test abnormal ": 4.811073366313274, "Coagulation time prolonged ": 11.451774500120958, "Coagulopathy ": 4.430188697001353, "Colonic haematoma ": 45.76330366533475, "Coma scale abnormal ": 2.9098652366409574, "Compartment syndrome ": 2.112383925938182, "Conjunctival haemorrhage ": 10.014906575958348, "Conjunctival pallor ": 64.68798546849972, "Contraindicated product administered ": 2.2802936992207106, "Contraindicated product prescribed ": 4.03797702723031, "Contusion ": 2.465483121837764, "Coronary artery bypass ": 3.4960660241213137, "Coronary artery disease ": 3.9681945353950256, "Coronary artery dissection ": 10.746012386085818, "Coronary artery occlusion ": 5.421516357231493, "Coronary artery restenosis ": 11.349834853441555, "Coronary artery stenosis ": 8.224778238425733, "Coronary artery thrombosis ": 17.235388235048, "Cystitis ": 5.500564599054324, "Degenerative mitral valve disease ": 369.3459951479402, "Dermatitis exfoliative ": 2.50320878258883, "Device occlusion ": 6.1674818016265816, "Diarrhoea haemorrhagic ": 3.859514856832439, "Diastolic dysfunction ": 2.8967512327550278, "Discoloured vomit ": 11.3568209162791, "Diverticulum intestinal ": 2.226328070478785, "Diverticulum intestinal haemorrhagic ": 23.18386310420243, "Drug interaction ": 3.2665679442574227, "Drug resistance ": 3.827997398253055, "Drug-induced liver injury ": 2.684328374598619, "Duodenal ulcer ": 14.145456916298343, "Duodenal ulcer haemorrhage ": 21.64267972970896, "Duodenitis ": 10.954179234659096, "Dyspnoea at rest ": 3.450205573618499, "ECG signs of myocardial ischaemia ": 24.65973361642249, "Ear haemorrhage ": 2.8458389050122754, "Ecchymosis ": 14.287845017436704, "Ejection fraction decreased ": 2.8981634519498822, "Electrocardiogram Q wave abnormal ": 23.073940228132265, "Electrocardiogram ST segment depression ": 4.597917388514503, "Electrocardiogram ST segment elevation ": 4.074587902460815, "Embolic stroke ": 5.853511918684582, "Epigastric discomfort ": 6.030895634193687, "Epistaxis ": 6.042068347876902, "Erosive oesophagitis ": 3.279090839059202, "Eructation ": 2.8943102439115744, "Extradural haematoma ": 26.784113594487632, "Extravasation blood ": 7.332865957705076, "Eye haemorrhage ": 2.7575271147324703, "Faecaloma ": 2.1016806750942885, "Faeces discoloured ": 14.034428357217305, "Faeces hard ": 2.8722254461183514, "Fibromyalgia ": 4.020542991004923, "Fluid retention ": 4.099905228238516, "Gastric haemorrhage ": 14.538314558803004, "Gastric mucosal lesion ": 29.458280417869894, "Gastric occult blood positive ": 92.89624782817133, "Gastric polyps ": 3.484345687677149, "Gastric ulcer ": 10.656456292134433, "Gastric ulcer haemorrhage ": 14.20601063714873, "Gastritis ": 2.9372411127720413, "Gastritis erosive ": 17.864335142966205, "Gastritis haemorrhagic ": 6.033586441626283, "Gastrointestinal angiodysplasia ": 8.921760517344792, "Gastrointestinal erosion ": 9.094701559184733, "Gastrointestinal haemorrhage ": 21.18256151102046, "Gastrointestinal polyp haemorrhage ": 10.278543701339492, "Gastrointestinal ulcer ": 4.471895555675629, "Gastrointestinal ulcer haemorrhage ": 29.438597113229463, "Gastrointestinal vascular malformation haemorrhagic ": 13.663792869126898, "Genital haemorrhage ": 3.386717615947022, "Gingival bleeding ": 8.3446496005831, "Gouty arthritis ": 5.895164156482704, "Gynaecomastia ": 2.200967300385809, "Haemarthrosis ": 2.2725792155679425, "Haematemesis ": 26.56258282486024, "Haematochezia ": 13.645708397845585, "Haematocrit decreased ": 2.103426154553095, "Haematoma ": 6.404229353443926, "Haematoma muscle ": 11.336636315875763, "Haematuria ": 10.301576385550746, "Haemobilia ": 15.673936098548204, "Haemodynamic instability ": 4.745366518384548, "Haemoglobin abnormal ": 4.670267234407192, "Haemoglobin decreased ": 6.234886379317853, "Haemoperitoneum ": 4.929171367544738, "Haemoptysis ": 8.334232792604215, "Haemorrhage ": 6.083684213450085, "Haemorrhage intracranial ": 13.289600581470593, "Haemorrhage subcutaneous ": 29.29084204706705, "Haemorrhage urinary tract ": 15.200713485472326, "Haemorrhagic cerebral infarction ": 22.076405145247605, "Haemorrhagic diathesis ": 6.633822737918919, "Haemorrhagic disorder ": 2.9681909075899995, "Haemorrhagic erosive gastritis ": 19.70840956180619, "Haemorrhagic infarction ": 22.542772065178504, "Haemorrhagic stroke ": 5.261956464789226, "Haemorrhagic transformation stroke ": 21.22556176377692, "Haemorrhoidal haemorrhage ": 6.314302532514554, "Haemothorax ": 14.623208397234476, "Heart failure with reduced ejection fraction ": 8.198624856700048, "Heart sounds abnormal ": 6.198842025354285, "Helicobacter test positive ": 5.98689183606869, "Hemiparesis ": 3.952761704056571, "Hemiplegia ": 3.0858023232308294, "Hepatic cyst ": 2.239564526449165, "Hepatic enzyme abnormal ": 3.489933948304826, "Hepatojugular reflux ": 32.14990981262236, "Hernia ": 2.160702890925544, "Hydrocephalus ": 3.774310683076077, "Hyphaema ": 13.369445891243243, "Hypomagnesaemia ": 2.0345571342017026, "Hypoproteinaemia ": 2.0232260218516545, "Hypovolaemic shock ": 3.711692640599576, "Inadequate analgesia ": 2.095703131777292, "Incorrect dosage administered ": 2.9078052897758204, "Increased tendency to bruise ": 3.346996636336995, "Infective exacerbation of chronic obstructive airways disease ": 7.596002163034264, "Inferior vena cava dilatation ": 20.89760281240041, "Insulin autoimmune syndrome ": 41.55928355147467, "Intermittent claudication ": 4.1878062640327816, "Internal haemorrhage ": 2.707054022941178, "Intestinal haematoma ": 10.42984206444636, "Intestinal haemorrhage ": 7.588197071354648, "Intestinal ischaemia ": 2.246694967618632, "Intra-abdominal haematoma ": 4.639135301849243, "Intra-abdominal haemorrhage ": 6.322121133285243, "Intracranial haematoma ": 19.586023268805896, "Intraventricular haemorrhage ": 14.51566134545476, "Iron deficiency anaemia ": 4.456147188090807, "Ischaemia ": 2.2545682429866, "Ischaemic cardiomyopathy ": 3.988724709882757, "Ischaemic hepatitis ": 13.578741053825404, "Ischaemic stroke ": 2.480939968419201, "Joint noise ": 2.1055990792331785, "Jugular vein distension ": 10.43206311564773, "Kounis syndrome ": 3.8459194677099817, "Labelled drug-disease interaction medication error ": 9.291289701054849, "Labelled drug-drug interaction issue ": 158.2656764770822, "Labelled drug-drug interaction medication error ": 157.08693147264688, "Labile hypertension ": 11.96470698346977, "Large intestinal haemorrhage ": 6.715140177953983, "Large intestinal ulcer ": 2.2214656111340023, "Left ventricular dysfunction ": 4.395230166769288, "Left ventricular hypertrophy ": 2.5233553145116003, "Lip erosion ": 5.809397809441265, "Lip haemorrhage ": 6.9612232472192535, "Lower gastrointestinal haemorrhage ": 37.284092462076295, "Lung hyperinflation ": 5.733094397337681, "Lymphadenopathy mediastinal ": 3.067998196657192, "Lymphoedema ": 14.249488569813913, "Mallory-Weiss syndrome ": 10.865425450974785, "Mean cell haemoglobin decreased ": 6.658986189078273, "Mediastinal haematoma ": 53.67010567280488, "Medication error ": 2.0525608085852287, "Melaena ": 40.16938217847586, "Microcytic anaemia ": 3.553955417121922, "Minimal residual disease ": 9.27448047184934, "Mitral valve disease ": 3.0435752408174177, "Mitral valve incompetence ": 2.904069873189179, "Mouth haemorrhage ": 6.025420022427461, "Mucosal haemorrhage ": 9.850598780435396, "Muscle haemorrhage ": 5.12379450647086, "Myocardial infarction ": 2.435864937934077, "Myocardial ischaemia ": 2.6694494034922736, "Myocardial necrosis marker increased ": 6.676080168420926, "N-terminal prohormone brain natriuretic peptide increased ": 14.236723301531814, "Neutrophil percentage increased ": 4.184973554682112, "Nikolsky's sign ": 5.951958197405623, "Nipple swelling ": 29.11222027064911, "Non-small cell lung cancer recurrent ": 29.17608234903769, "Normocytic anaemia ": 4.2148065615427885, "Obstructive sleep apnoea syndrome ": 2.3871152939624887, "Occult blood ": 11.73133023751578, "Occult blood positive ": 45.37271107912906, "Oesophageal haemorrhage ": 7.986215871109961, "Oesophageal intramural haematoma ": 64.70018974451897, "Oesophageal pain ": 6.793475314256406, "Oesophageal spasm ": 20.317414140912863, "Oesophageal ulcer ": 4.118372943234711, "Oesophagitis ": 2.678482801731417, "Orthopnoea ": 5.545925999150536, "Pallor ": 2.539166176506703, "Paraplegia ": 5.954199184311182, "Peptic ulcer ": 5.363863610229037, "Peptic ulcer haemorrhage ": 24.48181441598375, "Percutaneous coronary intervention ": 14.56132232579404, "Pericardial haemorrhage ": 17.07358004808956, "Peripheral arterial occlusive disease ": 2.483426744165686, "Peripheral artery occlusion ": 2.3722351744245707, "Peripheral artery thrombosis ": 2.864715582791518, "Petechiae ": 3.818921652573308, "Pharyngeal disorder ": 2.3326561609602443, "Pharyngeal haematoma ": 36.49302472931458, "Pharyngeal haemorrhage ": 5.428654464416129, "Pituitary enlargement ": 19.083623760488734, "Pituitary tumour benign ": 4.303349556426392, "Platelet count increased ": 2.342417069614416, "Platelet disorder ": 2.004966686174166, "Polyarthritis ": 2.6529248914234174, "Post procedural haematoma ": 9.270539631213488, "Post procedural haemorrhage ": 13.04822598588826, "Potentiating drug interaction ": 4.426172754512345, "Prerenal failure ": 4.850860782404132, "Prescribed underdose ": 3.195652594005692, "Prescription drug used without a prescription ": 2.604691817051813, "Primary adrenal insufficiency ": 25.63798001918226, "Procedural haemorrhage ": 18.24911069287091, "Product administration error ": 4.830460958153646, "Product monitoring error ": 6.712555036788778, "Product prescribing issue ": 11.744262975471695, "Product substitution issue ": 3.3441673211103127, "Prognathism ": 24.912736912382098, "Prostatomegaly ": 8.28124846984374, "Prothrombin time prolonged ": 3.5260905952348103, "Pulmonary alveolar haemorrhage ": 7.845440911121792, "Pulmonary haematoma ": 45.76330366533475, "Pulmonary haemorrhage ": 8.600919746395673, "Puncture site haemorrhage ": 17.030212021236384, "Purpura ": 3.7683194500790975, "Putamen haemorrhage ": 10.724361031970002, "Quadriparesis ": 4.073651944482668, "Quadriplegia ": 3.2483733171611955, "Rales ": 4.227284391479579, "Reaction to excipient ": 3.678237880481062, "Rectal haemorrhage ": 5.51232751021054, "Rectal ulcer ": 4.181403101425805, "Rectal ulcer haemorrhage ": 13.970288994597087, "Regurgitation ": 3.09817105176537, "Renal haemorrhage ": 6.3585421998165375, "Respiratory rate increased ": 6.178410266384722, "Respiratory tract haemorrhage ": 28.571753214530126, "Retinal haemorrhage ": 3.5420136011383647, "Retroperitoneal haematoma ": 18.09341681949948, "Retroperitoneal haemorrhage ": 17.724427985785972, "Rhonchi ": 3.256334380081722, "Shock haemorrhagic ": 15.448649536824144, "Skin flap necrosis ": 241.16165023190663, "Skin haemorrhage ": 3.939928753270861, "Sleep apnoea syndrome ": 3.421456930786577, "Small intestinal haemorrhage ": 16.24375573160993, "Spinal cord compression ": 4.474111210145527, "Spinal cord haemorrhage ": 15.616090848216595, "Spinal epidural haematoma ": 83.51557605253906, "Spinal subarachnoid haemorrhage ": 101.41288873084667, "Spinal subdural haematoma ": 18.597963196437632, "Spontaneous haematoma ": 7.050913568777228, "Spontaneous haemorrhage ": 8.399404948862976, "Stenosis ": 8.50364786324503, "Stent placement ": 3.002922545190721, "Stress ulcer ": 45.169186461719256, "Subarachnoid haemorrhage ": 13.206684871597894, "Subcutaneous haematoma ": 15.054068821658628, "Subdural haematoma ": 12.624267404495336, "Subdural haemorrhage ": 11.667877528911731, "Systemic inflammatory response syndrome ": 2.806224503145955, "Systolic dysfunction ": 6.265087614804869, "Testicular operation ": 181.5807334887051, "Testicular pain ": 2.894247738709812, "Testicular swelling ": 9.797689393279754, "Thalamus haemorrhage ": 9.871162068719578, "Therapeutic response increased ": 3.769482228217407, "Thrombosis in device ": 19.279328379438024, "Thrombotic thrombocytopenic purpura ": 11.538927724944218, "Tongue haemorrhage ": 11.220882473796092, "Tooth socket haemorrhage ": 18.393981687579338, "Tracheal haemorrhage ": 19.196020756998227, "Transfusion ": 2.2015660794345746, "Transient ischaemic attack ": 3.0829146166854566, "Traumatic haematoma ": 3.863633052239384, "Traumatic intracranial haemorrhage ": 3.936149757584813, "Tricuspid valve incompetence ": 3.489456976490016, "Troponin I increased ": 4.151962780834352, "Troponin increased ": 4.120204313169427, "Tumour haemorrhage ": 6.104643621525225, "Upper gastrointestinal haemorrhage ": 88.80658327964588, "Urethral haemorrhage ": 15.225698256521856, "Urinary bladder haemorrhage ": 10.383615459219037, "Urinary occult blood positive ": 9.7322779630798, "Urogenital haemorrhage ": 17.007714735917535, "Varices oesophageal ": 2.119029957975615, "Vascular injury ": 5.880760708752113, "Vascular pseudoaneurysm ": 29.24821033602416, "Vascular pseudoaneurysm ruptured ": 37.91017685665359, "Vascular stent occlusion ": 13.335926128647149, "Vascular stent stenosis ": 30.14483793828569, "Vascular stent thrombosis ": 49.49765835537662, "Venous occlusion ": 2.7225428198404957, "Ventricular hypokinesia ": 5.800013798325373, "Ventricular tachycardia ": 2.553990895478468, "Vessel puncture site haematoma ": 19.251765545116157, "Vitreous haemorrhage ": 4.172675890538603, "Volvulus ": 3.915238652128057, "Weight abnormal ": 4.88290838968886, "Wound haemorrhage ": 7.108186267693341, "Wound secretion ": 2.2757034980706203}
\ No newline at end of file
+{"Abnormal dreams": 11.465604490786784, "Aggression": 5.947004397993815, "Agitation": 7.1478951115526215, "Agranulocytosis": 4.245743534894539, "Akathisia": 9.333845112202145, "Confusional state": 2.739433826776972, "Depressed mood": 2.291865086084391, "Disorientation": 3.2616248585858125, "Disturbance in attention": 2.272031838453262, "Dry mouth": 2.585894674187002, "Epilepsy": 3.9065289112923858, "Flatulence": 4.706691963483168, "Hallucination": 2.4172366783909487, "Hepatic cytolysis": 4.117291280695244, "Hyperthyroidism": 3.968890502049475, "Hyponatraemia": 2.610295710324878, "Incorrect product administration duration": 7.978143020267403, "Initial insomnia": 12.786826748189362, "Insomnia": 3.0486810359517484, "Intentional overdose": 12.446035773319412, "Intentional self-injury": 30.720896867071737, "Irritability": 3.2311703806684937, "Labelled drug-drug interaction medication error": 14.852121223881658, "Middle insomnia": 21.07027534721172, "Mixed liver injury": 34.87244284217698, "Nervousness": 2.648308451035515, "Night sweats": 3.661918913374096, "Nightmare": 16.279928442093993, "Nocturia": 11.33478305423614, "Off label use": 2.3501918374837323, "Overdose": 4.953701314060728, "Palpitations": 2.4883188312117897, "Poor quality sleep": 10.39316768658454, "Prescribed overdose": 11.727236751747808, "Product administered to patient of inappropriate age": 237.60224187662067, "Product use issue": 3.6287814862931618, "Purpura": 10.53706242415973, "Rash macular": 3.895195151923355, "Rash maculo-papular": 5.624580362637078, "Restless legs syndrome": 10.03443665016759, "Restlessness": 8.214509521560892, "Sedation": 5.800682164551576, "Sleep disorder": 3.328391424298381, "Somnolence": 7.87756444381037, "Suicide attempt": 4.480373400572181, "Vision blurred": 2.474553016854664, "Wrong technique in product usage process": 4.568922209900865}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/278.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/278.json
index 2f420824c84..29c920b38d4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/278.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/278.json
@@ -1 +1 @@
-{"Accidental overdose ": 2.514865300231997, "Acidosis ": 4.435461632008114, "Acute kidney injury ": 13.186208718199692, "Agranulocytosis ": 2.2035560940444507, "Altered state of consciousness ": 2.591545190946273, "Angioedema ": 5.2400299785809406, "Anuria ": 3.291196575171782, "Atrioventricular block ": 3.5712353484475465, "Basal cell carcinoma ": 3.7162404085982494, "Blood creatinine increased ": 3.3341121808779857, "Blood glucose fluctuation ": 2.14268050708492, "Blood potassium decreased ": 2.9770733210781364, "Blood potassium increased ": 3.1522324441674123, "Blood pressure decreased ": 2.2726369201445618, "Blood pressure inadequately controlled ": 6.263666661721709, "Blood pressure increased ": 3.808341138846553, "Blood urea increased ": 2.79195058802337, "Blood uric acid increased ": 12.075710679106928, "Bone marrow failure ": 3.4775640447248573, "Bradycardia ": 4.847306922936101, "Cholestasis ": 2.702334436723396, "Colitis microscopic ": 10.291952883887742, "Confusional state ": 3.013941512843148, "Dehydration ": 3.976409313211781, "Dermatitis bullous ": 3.174139406262642, "Diabetes mellitus ": 2.5861781551644336, "Diabetic retinopathy ": 6.396099907645613, "Drug interaction ": 2.8541537934677623, "Drug level above therapeutic ": 12.404933993307871, "Eczema ": 2.304956378315354, "Electrolyte imbalance ": 5.665841999216865, "Eosinophilia ": 2.918363279119889, "Erectile dysfunction ": 4.266488512177378, "Fall ": 3.4922324752691507, "Femur fracture ": 2.3228316756815297, "Foetal monitoring abnormal ": 126.25983099074926, "Gout ": 2.684067517831332, "Haemolytic anaemia ": 2.2740943908133997, "Hepatic cytolysis ": 2.0847063666885, "Hepatitis ": 3.0447273944044584, "Hepatitis acute ": 2.6679218721102904, "Hepatitis cholestatic ": 6.322536131043499, "Hyperammonaemia ": 3.864671508894976, "Hypercalcaemia ": 3.539420538430375, "Hyperglycaemia ": 2.199444625078534, "Hyperkalaemia ": 14.102096608080023, "Hyperlactacidaemia ": 18.75535041828944, "Hypertension ": 2.336777747933982, "Hypertensive crisis ": 8.96606469471373, "Hyperuricaemia ": 11.60637674483948, "Hypochloraemia ": 38.136611886493945, "Hypoglycaemia neonatal ": 18.34306649100582, "Hypokalaemia ": 22.442198740846703, "Hypomagnesaemia ": 3.831961575319198, "Hyponatraemia ": 41.92083150239086, "Hypotension ": 6.107902829432936, "Hypovolaemic shock ": 7.784462777975893, "Inappropriate antidiuretic hormone secretion ": 15.095216283796704, "Interstitial lung disease ": 2.0881863396738662, "Lactic acidosis ": 11.38974419366384, "Medication error ": 4.1382477360439855, "Metabolic acidosis ": 3.7134303281364462, "Oedema peripheral ": 2.6262445763556563, "Oliguria ": 4.8998604666256425, "Orthostatic hypotension ": 17.156338726044677, "Pancreatic carcinoma ": 4.1424290065537965, "Pancreatitis acute ": 5.01959918926064, "Pancytopenia ": 2.0262058440159234, "Photosensitivity reaction ": 4.377082299707135, "Pollakiuria ": 2.082827240578652, "Product colour issue ": 14.589136290493936, "Product contamination microbial ": 407.8546500435292, "Rash maculo-papular ": 3.5207018007645474, "Red blood cell sedimentation rate increased ": 2.4363626137069585, "Renal failure ": 3.9826223539431886, "Rhabdomyolysis ": 2.545874650105217, "Sensory loss ": 3.473306909192497, "Septic shock ": 2.5138671013588394, "Sexual dysfunction ": 3.476057189132695, "Syncope ": 2.074356053283523, "Therapy non-responder ": 4.580113763582156, "Thrombocytopenia ": 2.0004592742243594, "Thrombocytopenic purpura ": 7.531581166139762, "Tinnitus ": 2.1187803314035234, "Tongue oedema ": 4.347240129858233, "Toxic skin eruption ": 8.024413850109012, "Type 2 diabetes mellitus ": 4.672413457709076, "Vertigo ": 2.46631520178594, "Wrong technique in product usage process ": 3.186597936991189}
\ No newline at end of file
+{"Acute myeloid leukaemia": 26.95991085574286, "Acute myeloid leukaemia recurrent": 44.4351582225848, "Agranulocytosis": 2.229961320590616, "Anaemia": 3.1795585367162804, "Aspergillus infection": 23.72396171552516, "Bronchopulmonary aspergillosis": 25.875245747296983, "Clostridium bacteraemia": 1951.404557212722, "Clostridium difficile infection": 6.050339868115159, "Cytopenia": 6.400501630607218, "Demodicidosis": 2691.150075743304, "Disease progression": 3.277976909341382, "Disease recurrence": 6.574823311959797, "Enterococcal infection": 53.361230371685146, "Febrile neutropenia": 22.613322623874133, "Haematotoxicity": 13.191364244338963, "Hairy cell leukaemia": 1192.8535201374905, "Hairy cell leukaemia recurrent": 4026.426509953304, "Hyperbilirubinaemia": 5.3307654304797305, "Hypoalbuminaemia": 16.897952572894162, "Incorrect dose administered": 3.841706100586476, "Infection": 2.47138830435394, "Langerhans' cell histiocytosis": 353.5099699955909, "Leukopenia": 4.426961804072266, "Lymphocyte count decreased": 29.096443801251997, "Lymphopenia": 68.60171828001596, "Multiple organ dysfunction syndrome": 6.776406454162983, "Multiple sclerosis": 8.697898074090764, "Multiple sclerosis relapse": 15.468165152158816, "Myelodysplastic syndrome": 62.71173076078217, "Myelosuppression": 6.636422631566398, "Neoplasm progression": 2.036846009373656, "Neutropenia": 8.55148244812126, "Neutropenic colitis": 98.39650481119038, "Neutrophil count decreased": 2.68346228632373, "Off label use": 4.625331269197818, "Pancytopenia": 38.05327934755389, "Pneumonia": 2.0884606180756675, "Product use in unapproved indication": 12.228632595667632, "Rash maculo-papular": 8.101883665945678, "Respiratory failure": 3.975261520275673, "Sepsis": 6.013921982201979, "Septic shock": 3.034908918079554, "Therapeutic product effect incomplete": 3.4416138160063747, "Thrombocytopenia": 6.115328617874013, "Toxic skin eruption": 4.759930335350683, "White blood cell count decreased": 2.098282960000108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/279.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/279.json
index 9b1905f043e..0ec4e358a12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/279.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/279.json
@@ -1 +1 @@
-{"Cushing's syndrome ": 128.47280675885344, "Drug interaction ": 12.50292349957808, "Immune reconstitution inflammatory syndrome ": 188.4828077047642, "Neuropathy peripheral ": 6.75889587018508}
\ No newline at end of file
+{"Disease recurrence": 25.073184236406327, "Drug hypersensitivity": 18.57834032816597, "Drug ineffective": 2.35548133619272, "Joint range of motion decreased": 43.14517161657622, "Lyme disease": 251.095139031637, "Pneumonia": 6.791509675905045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/28.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/28.json
index fa221225945..eefe8ee0c72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/28.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/28.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 12.476180096397185, "Blood creatine phosphokinase increased ": 15.445436409911636, "Blood creatinine increased ": 12.223504211243814, "Blood phosphorus decreased ": 505.4596392655991, "Bone pain ": 6.414905892664548, "Drug ineffective ": 5.305748725842466, "Drug resistance ": 162.91823534825764, "Fanconi syndrome acquired ": 68.25145392066845, "Hepatic function abnormal ": 3.9970933837906446, "Hepatitis B DNA increased ": 541.6693372279842, "Osteoporosis ": 4.717083502807063, "Pathogen resistance ": 51.170480911540366, "Product complaint ": 22.58273994844667, "Renal failure ": 2.0294314169901075, "Renal impairment ": 7.132376516903422, "Renal injury ": 3.734831100977009, "Viral infection ": 24.28293418155065, "Viral load increased ": 155.48106806424838}
\ No newline at end of file
+{"Abdominal distension": 3.6878005562341896, "Aneurysm": 14.896472493686606, "Angina pectoris": 5.8131658178941805, "Ascites": 8.199063021325125, "Atelectasis": 9.607014183201295, "Bladder neoplasm": 214.99198798090544, "Blood immunoglobulin G increased": 54.19663242197809, "Blood pressure abnormal": 4.480595491442218, "Blood pressure decreased": 3.240273335753493, "Blood pressure diastolic decreased": 16.461796133706606, "Blood pressure systolic decreased": 18.167031387000517, "Brain natriuretic peptide increased": 35.71120497221266, "Bronchiectasis": 7.228203542577359, "Cachexia": 14.178485024584898, "Cardiac cirrhosis": 466.59213295219536, "Cardiac failure": 5.703628778985032, "Cardiac failure congestive": 2.287401293495339, "Cardiomegaly": 5.1029667003308985, "Catheter site erythema": 31.09215039085773, "Catheter site infection": 23.725707624537367, "Catheter site pain": 58.61882840648245, "Catheter site swelling": 105.13386574166655, "Central venous catheterisation": 25.697394403942678, "Cholelithiasis": 2.6940427654210564, "Colitis": 2.3153162566123444, "Complication associated with device": 19.1108755301152, "Concomitant disease aggravated": 10.458245977333153, "Delirium": 5.184076086513179, "Device dislocation": 23.1153981589487, "Device related infection": 16.910098237378843, "Drug hypersensitivity": 2.5610156637265917, "Duodenitis": 24.60719711684903, "Dyspnoea exertional": 7.401277973368491, "Dysstasia": 2.4250174265014217, "Eosinophil count increased": 4.262994294792495, "Eosinophilic oesophagitis": 54.69795916037025, "Eosinophilic pneumonia": 10.657785189773763, "Episcleritis": 63.65494520700914, "Epistaxis": 2.460733512122954, "Exercise tolerance decreased": 4.6828264657273495, "Fall": 2.7223646547971345, "Feeling abnormal": 2.0239699340449557, "Fluid retention": 10.58654439901657, "Flushing": 5.008542459656376, "Focal nodular hyperplasia": 119.50748750356352, "Gamma-glutamyltransferase": 212.78407609137832, "Gastrointestinal pain": 4.7052299480691335, "Gastrointestinal wall thickening": 60.44190481972753, "Haematemesis": 2.932683072765768, "Haematocrit decreased": 2.7382750792997625, "Haemoptysis": 6.78110142447869, "Hepatic cirrhosis": 7.033824432351459, "Hiccups": 8.123789971034313, "Hospitalisation": 6.2916768251943065, "Hot flush": 2.624695088920644, "Hyperlipidaemia": 4.939578954714165, "Hyperplasia of thymic epithelium": 3312.9141942980823, "Hypersplenism": 136.82930560037616, "Hypervolaemia": 21.72081284231022, "Hypotension": 2.422573634373008, "Hypovolaemia": 10.658654492853346, "Hypoxia": 6.086202415632863, "Interstitial lung disease": 2.3807064037286896, "Iron deficiency anaemia": 11.760869986450256, "Left ventricular failure": 14.08996904100706, "Lipase increased": 4.9118258206569845, "Liver disorder": 3.237375237492586, "Localised infection": 3.919718180451196, "Mallory-Weiss syndrome": 62.22821080783974, "Mediastinal disorder": 206.16236740389, "Mental status changes": 2.539406521659177, "Nasal congestion": 4.0079430509532, "Occult blood positive": 22.21482856195279, "Oedema": 4.344012397501819, "Oedema peripheral": 2.731917282399665, "Overlap syndrome": 169.2042777497253, "Oxygen saturation decreased": 14.281816804640364, "Pain in jaw": 22.686402456831495, "Pericardial effusion": 6.914063135777443, "Peripheral swelling": 3.807379056808041, "Pharyngeal oedema": 5.8371633722833005, "Platelet count decreased": 3.2246804373193183, "Platelet transfusion": 63.65494520700914, "Pneumonia bacterial": 9.63258671527971, "Portal fibrosis": 493.2699308308524, "Portal hypertensive gastropathy": 190.1001047735297, "Portal tract inflammation": 435.214280130478, "Pulmonary alveolar haemorrhage": 7.579080276744194, "Pulmonary arterial hypertension": 34.03274727586867, "Pulmonary congestion": 6.701267320435047, "Pulmonary hypertension": 17.367461238321393, "Pulmonary oedema": 8.874527907168225, "Renal disorder": 2.261507138913037, "Respiratory distress": 2.0510171629656075, "Respiratory failure": 2.3918983790054686, "Respiratory syncytial virus infection": 24.41211866780808, "Retroperitoneal lymphadenopathy": 103.74743064531977, "Right ventricular failure": 31.74211611495988, "Scleroderma": 42.51443995325182, "Serum ferritin decreased": 30.863988873807475, "Splenomegaly": 5.445091695802707, "Sputum retention": 49.06237616204141, "Syncope": 2.6540463163284045, "Systemic scleroderma": 81.24768652958652, "Transfusion": 5.3137371965168825, "Troponin increased": 6.494352890782109, "Varices oesophageal": 21.885270361976197, "Vascular device infection": 40.55112942673605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/280.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/280.json
index 7bd8b87fdda..c5facc0dee5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/280.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/280.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 3.054318742262958, "Anaemia ": 3.337285436015043, "Aspartate aminotransferase increased ": 3.2532484745277603, "Blood creatine phosphokinase increased ": 12.510191807163729, "Blood creatinine increased ": 2.1760195622491394, "Central serous chorioretinopathy ": 172.46883419062755, "Dermatitis acneiform ": 48.64992690740817, "Diarrhoea ": 2.8729822014579907, "Disease progression ": 4.682372325787644, "Drug reaction with eosinophilia and systemic symptoms ": 45.40716088385664, "Ejection fraction decreased ": 10.289766375109766, "Electrocardiogram QT prolonged ": 3.440272932233699, "Erythema ": 2.433090500088479, "Gamma-glutamyltransferase increased ": 3.527311734242254, "Hepatotoxicity ": 9.1304284538417, "Hyperkeratosis ": 35.02899556986354, "Intentional product use issue ": 2.4471090168077203, "Malignant neoplasm progression ": 4.469167450252903, "Metastases to central nervous system ": 20.20165330636985, "Metastatic malignant melanoma ": 95.22920200409833, "Myositis ": 14.818580655751855, "Photosensitivity reaction ": 35.91514071915189, "Pneumonia viral ": 51.45739142043528, "Rash ": 3.806744643833321, "Rash maculo-papular ": 18.162863555680005, "Retinal detachment ": 19.79946613171682, "Retinopathy ": 28.878223960038437, "Skin toxicity ": 179.22251002033113, "Therapy partial responder ": 27.37242856250962, "Toxic skin eruption ": 13.451074447133037, "Transaminases increased ": 4.707810596005276, "Uveitis ": 29.866612985821803}
\ No newline at end of file
+{"Acute lymphocytic leukaemia": 81.50811653228288, "Acute myeloid leukaemia": 31.76048968967356, "Acute myeloid leukaemia recurrent": 66.45208138161259, "Anaemia": 2.7672194994595105, "Aspergillus infection": 31.13863881843494, "Bone marrow failure": 45.64731766443301, "Capillary leak syndrome": 113.56356207144614, "Cellulitis": 7.785494328399304, "Colitis": 5.1551841796299085, "Disease progression": 6.142890052573388, "Drug resistance": 5.220164781447125, "Febrile neutropenia": 21.71906540082924, "Fusarium infection": 322.4011120110772, "Hepatotoxicity": 7.595775336717903, "Hyperbilirubinaemia": 12.53120197398825, "Infection": 3.0705472904990945, "Klebsiella sepsis": 136.05771328017923, "Leukaemia recurrent": 77.08779789168332, "Lymphopenia": 23.736809040512, "Malignant neoplasm progression": 2.6297882588930475, "Mucosal inflammation": 10.625306983762046, "Multiple organ dysfunction syndrome": 18.03431775606538, "Neoplasm progression": 3.410873043513219, "Neutropenia": 6.956608101517416, "Off label use": 2.5812193011477773, "Palmar-plantar erythrodysaesthesia syndrome": 9.674008355036984, "Pancytopenia": 8.462996114289497, "Pneumonia": 2.3814190786406546, "Product use in unapproved indication": 2.0162289293508686, "Product use issue": 4.355088636534059, "Pulmonary mass": 15.478337669749374, "Rash maculo-papular": 3.293765757246716, "Respiratory failure": 5.014569908633587, "Sepsis": 7.408162315464749, "Septic shock": 12.769989342297688, "Sinusitis": 5.567235863554169, "Stomatitis": 2.4413089805958617, "Swelling face": 2.897593172655154, "Therapy non-responder": 9.933278654759077, "Thrombocytopenia": 4.069724664084457, "Transaminases increased": 3.736612808460221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/281.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/281.json
index e2fc4ed7d3d..6a68c9b33b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/281.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/281.json
@@ -1 +1 @@
-{"Cerebrovascular accident ": 77.26568312142449, "Confusional state ": 36.001778756256506, "Death ": 5.762492945999524, "Disorientation ": 151.6179261085339, "Speech disorder ": 145.40084618508902}
\ No newline at end of file
+{"Abdominal distension": 2.1562082603479964, "Abdominal pain upper": 2.07311852226745, "Abdominal tenderness": 5.135010314676991, "Abdominal wall haematoma": 10.104299292350154, "Acquired haemophilia": 9.33152821413186, "Activated partial thromboplastin time prolonged": 3.4498388054222944, "Acute coronary syndrome": 4.993751042084176, "Acute myocardial infarction": 7.857839339693579, "Akinesia": 2.233863117215472, "Allergic cough": 14.710967828403213, "Amaurosis": 15.176292353004264, "Anaemia": 2.7360911272817208, "Anaemia macrocytic": 2.3454963663843547, "Anal haemorrhage": 3.812009074506384, "Angina pectoris": 3.490432957471067, "Angina unstable": 4.946172807737574, "Angiodysplasia": 12.6763895795205, "Angiopathy": 2.542832646766422, "Angioplasty": 4.126633324446446, "Anticoagulation drug level above therapeutic": 2.0848164222004635, "Aortic aneurysm": 2.361815470890023, "Aortic arteriosclerosis": 2.499746704909492, "Aortic stenosis": 3.038304375366083, "Aortic thrombosis": 6.208256403085688, "Aortic valve incompetence": 3.8155777000459272, "Aortic valve stenosis": 4.81689464087982, "Aphasia": 2.052403278373098, "Arterial haemorrhage": 20.585918367026107, "Arterial injury": 9.548688321080444, "Arterial rupture": 10.201078083172174, "Arterial thrombosis": 3.003646984661253, "Arteriosclerosis coronary artery": 2.1193245847616207, "Atheroembolism": 38.81257897783119, "Atrial thrombosis": 3.0745461655385844, "Basal ganglia haemorrhage": 7.159533611869396, "Behaviour disorder": 2.397348722444161, "Bladder disorder": 2.5340610656706213, "Bleeding time prolonged": 12.384953654361922, "Bleeding varicose vein": 7.966306504428912, "Blood albumin decreased": 2.197430984077875, "Blood aldosterone decreased": 54.18376866362588, "Blood cholesterol": 35.421811383094706, "Blood fibrinogen increased": 3.196805451438635, "Blood iron decreased": 3.9734008194129817, "Blood loss anaemia": 42.386385326079576, "Blood osmolarity increased": 16.90808374339688, "Blood pressure diastolic decreased": 5.753947477084918, "Blood pressure systolic abnormal": 7.434333747441004, "Blood pressure systolic decreased": 2.1591701468733207, "Body mass index decreased": 10.410289491850452, "Brain herniation": 10.440052970334332, "Brain stem haemorrhage": 15.603989572946706, "Bronchitis": 2.982209839950748, "Bundle branch block left": 2.6993710175693995, "Cardiac aneurysm": 15.272256681450065, "Cardiac death": 6.362345534430719, "Cardiac failure acute": 3.0453167882245884, "Cardiac failure chronic": 3.4794801650891003, "Cardiac fibrillation": 2.552840815928164, "Cardiac tamponade": 9.500841753139676, "Cardiac ventricular thrombosis": 6.588180327892893, "Cardiogenic shock": 2.33130480540848, "Carotid arteriosclerosis": 5.109050105697414, "Carotid artery occlusion": 2.512361572746627, "Carotid artery stenosis": 3.112290847149416, "Catheter site haematoma": 27.185684016112884, "Catheter site haemorrhage": 6.985577158159716, "Cerebellar haematoma": 8.89435614935851, "Cerebellar haemorrhage": 14.615309496059316, "Cerebral artery embolism": 5.47298794574258, "Cerebral haematoma": 15.959296920697764, "Cerebral haemorrhage": 8.629095042121566, "Cerebral infarction": 3.179937006234771, "Cerebral mass effect": 12.709476111082104, "Cerebral microhaemorrhage": 12.581219841159944, "Cholecystitis acute": 2.0954035666194213, "Chronic gastritis": 17.029143953551646, "Coagulation test abnormal": 4.806386963977912, "Coagulation time prolonged": 11.44061908335318, "Coagulopathy": 4.425872945623838, "Colonic haematoma": 45.71872649689318, "Coma scale abnormal": 2.907030737302004, "Compartment syndrome": 2.1103262895793646, "Conjunctival haemorrhage": 10.005150471794522, "Conjunctival pallor": 64.62497286823836, "Contraindicated product administered": 2.278072221466882, "Contraindicated product prescribed": 4.034043681886868, "Contusion": 2.4630811512057167, "Coronary artery bypass": 3.492660467900877, "Coronary artery disease": 3.964328773693144, "Coronary artery 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2.843066814679871, "Ecchymosis": 14.273925525292594, "Ejection fraction decreased": 2.895340246989217, "Electrocardiogram Q wave abnormal": 23.051464321675937, "Electrocardiogram ST segment depression": 4.5934385588576125, "Electrocardiogram ST segment elevation": 4.070618798675494, "Embolic stroke": 5.847809945800048, "Epigastric discomfort": 6.025020845618826, "Epistaxis": 6.043231134577408, "Erosive oesophagitis": 3.2758967292649244, "Eructation": 2.89149082852881, "Extradural haematoma": 26.75802225539789, "Extravasation blood": 7.325723156632959, "Eye haemorrhage": 2.7548409085949053, "Faecaloma": 2.099633444454991, "Faeces discoloured": 14.02075536770884, "Faeces hard": 2.869427641344468, "Fibromyalgia": 4.016626254302802, "Fluid retention": 4.139948373634221, "Gastric haemorrhage": 14.524151407664773, "Gastric mucosal lesion": 29.42958477837592, "Gastric occult blood positive": 92.80576009556243, "Gastric polyps": 3.4809516278014287, "Gastric ulcer": 10.6387139112476, "Gastric ulcer haemorrhage": 14.192171559513657, "Gastritis": 2.9343797874167845, "Gastritis erosive": 17.82632347946747, "Gastritis haemorrhagic": 6.027709141094727, "Gastrointestinal angiodysplasia": 8.913069979096663, "Gastrointestinal erosion": 9.08584256212102, "Gastrointestinal haemorrhage": 21.161918039554088, "Gastrointestinal polyp haemorrhage": 10.268531560226863, "Gastrointestinal ulcer": 4.467539541741807, "Gastrointestinal ulcer haemorrhage": 29.40992060296735, "Gastrointestinal vascular malformation haemorrhagic": 13.650483203155051, "Genital haemorrhage": 3.3834186295780944, "Gingival bleeding": 8.336520297498446, "Gouty arthritis": 5.889421773352323, "Gynaecomastia": 2.19882329765898, "Haemarthrosis": 2.270365470821049, "Haematemesis": 26.534114989742847, "Haematochezia": 13.630996166714706, "Haematocrit decreased": 2.1013771378914043, "Haematoma": 6.397989822647695, "Haematoma muscle": 11.325592706980371, "Haematuria": 10.291539385866756, "Haemobilia": 15.65866819502525, "Haemodynamic instability": 4.740743947282608, "Haemoglobin abnormal": 4.665717888877805, "Haemoglobin decreased": 6.2288114002979125, "Haemoperitoneum": 4.9243698637285584, "Haemoptysis": 8.326113218946862, "Haemorrhage": 6.07775660145784, "Haemorrhage intracranial": 13.276653416602986, "Haemorrhage subcutaneous": 29.262305548024155, "Haemorrhage urinary tract": 15.185905864956712, "Haemorrhagic cerebral infarction": 22.0549002494817, "Haemorrhagic diathesis": 6.6273605663488615, "Haemorrhagic disorder": 2.9652996448511435, "Haemorrhagic erosive gastritis": 19.689211922790243, "Haemorrhagic infarction": 22.52081310354528, "Haemorrhagic stroke": 5.329364590037511, "Haemorrhagic transformation stroke": 21.204885766957872, "Haemorrhoidal haemorrhage": 6.308151663415908, "Haemothorax": 14.6089634559228, "Heart failure with reduced ejection fraction": 8.190638656809508, "Heart sounds abnormal": 6.192803808717119, "Helicobacter test positive": 5.981060111650128, "Hemiparesis": 3.981111146306435, "Hemiplegia": 3.082796350094898, "Hepatic cyst": 2.237382995872468, "Hepatic enzyme abnormal": 3.4865343872054546, "Hepatojugular reflux": 32.11859324482533, "Hernia": 2.158598131741599, "Hydrocephalus": 3.7706340923345367, "Hyphaema": 13.356422923926104, "Hypomagnesaemia": 2.0325752546403506, "Hypoproteinaemia": 2.0212552326328943, "Hypovolaemic shock": 3.708077049892244, "Inadequate analgesia": 2.093661747231624, "Incorrect dosage administered": 2.904972819773449, "Increased tendency to bruise": 3.3437362930216934, "Infective exacerbation of chronic obstructive airways disease": 7.588603046351393, "Inferior vena cava dilatation": 20.87724680229958, "Insulin autoimmune syndrome": 41.51880028952999, "Intermittent claudication": 4.183726961089155, "Internal haemorrhage": 2.704417047087622, "Intestinal haematoma": 10.419682563016115, "Intestinal haemorrhage": 7.580805157289242, "Intestinal ischaemia": 2.2445064718409826, "Intra-abdominal haematoma": 4.634616317133382, "Intra-abdominal haemorrhage": 6.315962699384387, "Intracranial haematoma": 19.56694440516088, "Intraventricular haemorrhage": 14.50152125071638, "Iron deficiency anaemia": 4.450200582460544, "Ischaemia": 2.252372075374548, "Ischaemic cardiomyopathy": 3.984839274640039, "Ischaemic hepatitis": 13.565513983034974, "Ischaemic stroke": 2.4785231740103923, "Joint noise": 2.1035480486616303, "Jugular vein distension": 10.421901348256585, "Kounis syndrome": 3.842173225338009, "Labelled drug-disease interaction medication error": 9.28223912587372, "Labelled drug-drug interaction issue": 158.1114865001045, "Labelled drug-drug interaction medication error": 156.93384994489583, "Labile hypertension": 11.953052383727965, "Large intestinal haemorrhage": 6.708598971227058, "Large intestinal ulcer": 2.219301720234147, "Left ventricular dysfunction": 4.390948674428052, "Left ventricular hypertrophy": 2.5208973169365385, "Lip erosion": 5.803738930470665, "Lip haemorrhage": 6.954442404922289, "Lower gastrointestinal haemorrhage": 37.247769538225846, "Lung hyperinflation": 5.727509883609768, "Lymphadenopathy mediastinal": 3.0650096957908746, "Lymphoedema": 14.235607073042049, "Mallory-Weiss syndrome": 10.854841464256872, "Mean cell haemoglobin decreased": 6.652499718730822, "Mediastinal haematoma": 53.61782622724356, "Medication error": 2.0504130411242265, "Melaena": 40.12429531588605, "Microcytic anaemia": 3.550493551262321, "Minimal residual disease": 9.26544635532752, "Mitral valve disease": 3.0406105475462653, "Mitral valve incompetence": 2.9012409548876565, "Mouth haemorrhage": 6.019550413085313, "Mucosal haemorrhage": 9.841003312695188, "Muscle haemorrhage": 5.118803367750012, "Myocardial infarction": 2.433491704328799, "Myocardial ischaemia": 2.6668490283279875, "Myocardial necrosis marker increased": 6.6695769703259735, "N-terminal prohormone brain natriuretic peptide increased": 14.222854993739892, "Neutrophil percentage increased": 4.18089705252009, "Nikolsky's sign": 5.946160451823843, "Nipple swelling": 29.08386221681284, "Non-small cell lung cancer recurrent": 29.14766247431967, "Normocytic anaemia": 4.210700933230806, "Obstructive sleep apnoea syndrome": 2.38479002091944, "Occult blood": 11.71990281399106, "Occult blood positive": 45.32851017641858, "Oesophageal haemorrhage": 7.97843653009496, "Oesophageal intramural haematoma": 64.63716601844064, "Oesophageal pain": 6.786857665084271, "Oesophageal spasm": 20.297622648144188, "Oesophageal ulcer": 4.114361241667411, "Oesophagitis": 2.675873653081132, "Orthopnoea": 5.540523635352439, "Pallor": 2.536530659593345, "Paraplegia": 5.9483991309024695, "Peptic ulcer": 5.358638641868724, "Peptic ulcer haemorrhage": 24.457966352992624, "Percutaneous coronary intervention": 14.547138415030242, "Pericardial haemorrhage": 17.03384572616172, "Peripheral arterial occlusive disease": 2.481007649072837, "Peripheral artery occlusion": 2.369924421562978, "Peripheral artery thrombosis": 2.861925089651573, "Petechiae": 3.815201351644321, "Pharyngeal disorder": 2.330383961314307, "Pharyngeal haematoma": 36.45747748358459, "Pharyngeal haemorrhage": 5.423366477627594, "Pituitary enlargement": 19.065034741136685, "Pituitary tumour benign": 4.299157720822782, "Platelet count increased": 2.3401352799166206, "Platelet disorder": 2.0030136862538224, "Polyarthritis": 2.6503406571405006, "Post procedural haematoma": 9.261509207725378, "Post procedural haemorrhage": 13.035514719904429, "Potentiating drug interaction": 4.421861164374184, "Prerenal failure": 4.846135604642049, "Prescribed underdose": 3.1925396124730336, "Prescription drug used without a prescription": 2.602154607373573, "Primary adrenal insufficiency": 25.61300630511453, "Procedural haemorrhage": 18.231333611323365, "Product administration error": 4.825370284041592, "Product monitoring error": 6.706016385458204, "Product prescribing issue": 11.732822170999883, "Product substitution issue": 3.340909555007235, "Prognathism": 24.888469872035817, "Prostatomegaly": 8.273181587297264, "Prothrombin time prolonged": 3.5226557359986432, "Pulmonary alveolar haemorrhage": 7.8377983299823635, "Pulmonary haematoma": 45.71872649689318, "Pulmonary haemorrhage": 8.592541123741503, "Puncture site haemorrhage": 17.0136229974328, "Purpura": 3.764648514036423, "Putamen haemorrhage": 10.7139145146855, "Quadriparesis": 4.069683823479804, "Quadriplegia": 3.245209106698548, "Rales": 4.223166489829046, "Reaction to excipient": 3.674654909838543, "Rectal haemorrhage": 5.52257751579966, "Rectal ulcer": 4.17733007051339, "Rectal ulcer haemorrhage": 13.956680819426806, "Regurgitation": 3.095153148062004, "Renal haemorrhage": 6.352348354278576, "Respiratory rate increased": 6.172391619655951, "Respiratory tract haemorrhage": 28.54392114751265, "Retinal haemorrhage": 3.538563226128125, "Retroperitoneal haematoma": 18.075791158665453, "Retroperitoneal haemorrhage": 17.70716166016248, "Rhonchi": 3.253162436980803, "Shock haemorrhagic": 15.433599399971532, "Skin flap necrosis": 240.926742827478, "Skin haemorrhage": 3.934729819969421, "Sleep apnoea syndrome": 3.416591233167537, "Small intestinal haemorrhage": 16.227932248224924, "Spinal cord compression": 4.469752979966818, "Spinal cord haemorrhage": 15.600879400596808, "Spinal epidural haematoma": 83.43421984516698, "Spinal subarachnoid haemorrhage": 101.3141045569928, "Spinal subdural haematoma": 18.579847277266104, "Spontaneous haematoma": 7.04404517729167, "Spontaneous haemorrhage": 8.391223215807726, "Stenosis": 8.495364503741394, "Stent placement": 2.9999973626749927, "Stress ulcer": 45.12518794901735, "Subarachnoid haemorrhage": 13.193818809458882, "Subcutaneous haematoma": 15.039404078432211, "Subdural haematoma": 12.61196839097042, "Subdural haemorrhage": 11.656511457745468, "Systemic inflammatory response syndrome": 2.803490975491928, "Systolic dysfunction": 6.25898486101375, "Testicular operation": 181.403858989946, "Testicular pain": 2.8914284553867344, "Testicular swelling": 9.788145474410518, "Thalamus haemorrhage": 9.861546505244773, "Therapeutic response increased": 3.7658104307419937, "Thrombosis in device": 19.26054780031012, "Thrombotic thrombocytopenic purpura": 11.52768710071464, "Tongue haemorrhage": 11.209952261553411, "Tooth socket haemorrhage": 18.37606446250184, "Tracheal haemorrhage": 19.177322174650165, "Transfusion": 2.19942151314485, "Transient ischaemic attack": 3.079911294033941, "Traumatic haematoma": 3.859869555384456, "Traumatic intracranial haemorrhage": 3.932315623516863, "Tricuspid valve incompetence": 3.486057858211718, "Troponin I increased": 4.136118034083462, "Troponin increased": 4.116190685526284, "Tumour haemorrhage": 6.098697034186054, "Upper gastrointestinal haemorrhage": 88.68802437172413, "Urethral haemorrhage": 15.2108670295783, "Urinary bladder haemorrhage": 10.373500634344296, "Urinary occult blood positive": 9.722797886507577, "Urogenital haemorrhage": 16.991147819062622, "Varices oesophageal": 2.116965838518975, "Vascular injury": 5.875032347216606, "Vascular pseudoaneurysm": 29.219718816538325, "Vascular pseudoaneurysm ruptured": 37.87324914284613, "Vascular stent occlusion": 13.32293565092667, "Vascular stent stenosis": 30.115473029057103, "Vascular stent thrombosis": 49.449436238815615, "Venous occlusion": 2.719890838524212, "Ventricular hypokinesia": 5.794363938523667, "Ventricular tachycardia": 2.5515029347286253, "Vessel puncture site haematoma": 19.23301268817037, "Vitreous haemorrhage": 4.168611292573515, "Volvulus": 3.911424881232074, "Weight abnormal": 4.878152027819659, "Wound haemorrhage": 7.101262097677275, "Wound secretion": 2.2734867750049794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/282.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/282.json
index 8af1282c582..64edee8491d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/282.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/282.json
@@ -1 +1 @@
-{"Acute kidney injury ": 18.00772595547702, "Blood creatinine increased ": 4.721646151499575, "Drug ineffective ": 2.629436771359388, "Drug interaction ": 2.641293372751392, "Klebsiella infection ": 171.0713704104597, "Muscular weakness ": 3.946657388586083, "Neurotoxicity ": 38.40526030714968, "Overdose ": 3.398565002869733, "Pathogen resistance ": 60.92862420526939, "Vertigo ": 4.081051256129409}
\ No newline at end of file
+{"Accidental overdose": 2.5127974567089577, "Acidosis": 4.431814878563364, "Acute kidney injury": 13.175349303810188, "Agranulocytosis": 2.2017441041641512, "Altered state of consciousness": 2.5894141406469458, "Angioedema": 5.235719194187023, "Anuria": 3.2884906146518005, "Atrioventricular block": 3.568299145361176, "Basal cell carcinoma": 3.713184985108468, "Blood creatinine increased": 3.331369759813952, "Blood glucose fluctuation": 2.140918855768028, "Blood potassium decreased": 2.974625496828802, "Blood potassium increased": 3.1496406793946554, "Blood pressure decreased": 2.270694147978263, "Blood pressure inadequately controlled": 6.258516678420726, "Blood pressure increased": 3.805141144677527, "Blood urea increased": 2.789654954157086, "Blood uric acid increased": 12.06578080543801, "Bone marrow failure": 3.4747048564055536, "Bradycardia": 4.843167479385705, "Cholestasis": 2.7001124470919065, "Colitis microscopic": 10.28349103888724, "Confusional state": 3.0114619577517816, "Dehydration": 3.972925965748978, "Dermatitis bullous": 3.171529658204246, "Diabetes mellitus": 2.584051370606186, "Diabetic retinopathy": 6.390841283081872, "Drug interaction": 2.85180567779002, "Drug level above therapeutic": 12.394735019456135, "Eczema": 2.303061066754511, "Electrolyte imbalance": 5.66118340361966, "Eosinophilia": 2.9159635776616866, "Erectile dysfunction": 4.262980142201441, "Fall": 3.489269562563683, "Femur fracture": 2.3209219092083795, "Foetal monitoring abnormal": 126.15602394333156, "Gout": 2.6818607273557, "Haemolytic anaemia": 2.272224694746178, "Hepatic cytolysis": 2.082992220485159, "Hepatitis": 3.042223633695545, "Hepatitis acute": 2.6657284095909115, "Hepatitis cholestatic": 6.317337393354136, "Hyperammonaemia": 3.861494125388208, "Hypercalcaemia": 3.5365104278351827, "Hyperglycaemia": 2.197635865221809, "Hyperkalaemia": 14.08853721366368, "Hyperlactacidaemia": 18.739929330402667, "Hypertension": 2.3348311351679967, "Hypertensive crisis": 8.958691365123826, "Hyperuricaemia": 11.596833609948632, "Hypochloraemia": 38.10525427275213, "Hypoglycaemia neonatal": 18.32798518997678, "Hypokalaemia": 22.423724148243483, "Hypomagnesaemia": 3.828811045497, "Hyponatraemia": 41.886299178768, "Hypotension": 6.1027340474960114, "Hypovolaemic shock": 7.778062541058603, "Inappropriate antidiuretic hormone secretion": 15.082802055931031, "Interstitial lung disease": 2.086469001674572, "Lactic acidosis": 11.380374787915464, "Medication error": 4.134547413580035, "Metabolic acidosis": 3.710376765448314, "Oedema peripheral": 2.624019602863441, "Oliguria": 4.895831803362894, "Orthostatic hypotension": 17.138505777500352, "Pancreatic carcinoma": 4.139022703628517, "Pancreatitis acute": 5.015471040446294, "Pancytopenia": 2.024539605665115, "Photosensitivity reaction": 4.373483099353235, "Pollakiuria": 2.2241615139773634, "Product colour issue": 14.577141390268164, "Product contamination microbial": 407.5192329439657, "Rash maculo-papular": 3.5178062865855293, "Red blood cell sedimentation rate increased": 2.434359530230981, "Renal failure": 3.979345382967451, "Rhabdomyolysis": 2.5437810653694246, "Sensory loss": 3.470451221009223, "Septic shock": 2.511800042232108, "Sexual dysfunction": 3.473199309169909, "Syncope": 2.0726211821083123, "Therapy non-responder": 4.575946773172098, "Thrombocytopenic purpura": 7.525388993845739, "Tinnitus": 2.117037792442201, "Tongue oedema": 4.34366575620832, "Toxic skin eruption": 8.017814982646577, "Type 2 diabetes mellitus": 4.668571381059262, "Vertigo": 2.464286669970026, "Wrong technique in product usage process": 3.1839773380755174}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/283.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/283.json
index 1056aff606f..a3770d1c3a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/283.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/283.json
@@ -1 +1 @@
-{"Contusion ": 32.22100194002236, "Dupuytren's contracture ": 3283.2422052339657, "Incorrect dose administered ": 26.17725192161104, "Oedema peripheral ": 33.285720701347, "Skin laceration ": 564.5997339138858, "Tendon rupture ": 179.28475633377508}
\ No newline at end of file
+{"Cushing's syndrome": 128.47280675885344, "Drug interaction": 12.50292349957808, "Immune reconstitution inflammatory syndrome": 188.4828077047642, "Neuropathy peripheral": 6.758690707777434}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/284.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/284.json
index aa84956adb5..53b36e65391 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/284.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/284.json
@@ -1 +1 @@
-{"Cough ": 19.742984136044985, "Death ": 3.7444808560178986, "Dyspnoea ": 3.004947404963968, "Haemoptysis ": 26.677273143342997, "Off label use ": 3.560416305220404, "Pneumonia ": 4.677916912542848, "Product physical issue ": 173.9784084673403}
\ No newline at end of file
+{"Alanine aminotransferase increased": 3.054318742262958, "Anaemia": 3.337285436015043, "Aspartate aminotransferase increased": 3.2532484745277603, "Blood creatine phosphokinase increased": 12.510191807163729, "Blood creatinine increased": 2.1760195622491394, "Central serous chorioretinopathy": 172.46883419062755, "Dermatitis acneiform": 48.64992690740817, "Diarrhoea": 2.872958219620846, "Disease progression": 4.682372325787644, "Drug reaction with eosinophilia and systemic symptoms": 45.40339313184336, "Ejection fraction decreased": 10.289766375109766, "Electrocardiogram QT prolonged": 3.440272932233699, "Erythema": 2.433066698996057, "Gamma-glutamyltransferase increased": 3.527311734242254, "Hepatotoxicity": 9.1304284538417, "Hyperkeratosis": 35.02899556986354, "Intentional product use issue": 2.4471090168077203, "Malignant neoplasm progression": 4.469167450252903, "Metastases to central nervous system": 20.20165330636985, "Metastatic malignant melanoma": 95.22920200409833, "Myositis": 14.818580655751855, "Photosensitivity reaction": 35.91514071915189, "Pneumonia viral": 51.45739142043528, "Rash": 3.806692335515194, "Rash maculo-papular": 18.162863555680005, "Retinal detachment": 19.79946613171682, "Retinopathy": 28.878223960038437, "Skin toxicity": 178.96088006931797, "Therapy partial responder": 27.37242856250962, "Toxic skin eruption": 13.451074447133037, "Transaminases increased": 4.7075222628252815, "Uveitis": 29.866612985821803}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/285.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/285.json
index ae44e9a664f..8a7e3ec7a53 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/285.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/285.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.1397018103290275, "Abnormal dreams ": 2.402627690194404, "Abortion induced ": 20.807068118388536, "Abortion missed ": 15.92037670770376, "Abortion spontaneous ": 7.264560865183492, "Acquired gene mutation ": 24.0434142335154, "Acute pulmonary oedema ": 3.1330727746349, "Adenotonsillectomy ": 477.097705543272, "Adrenogenital syndrome ": 240.005173795878, "Adverse reaction ": 2.0468256303664703, "Alanine aminotransferase increased ": 4.1011758723239495, "Alpha 1 foetoprotein abnormal ": 229.0867695823449, "Alpha 1 foetoprotein increased ": 21.752127181864463, "Ammonia increased ": 3.869856930423088, "Amylase increased ": 3.834942172549373, "Anaemia ": 8.90731609033329, "Anaemia macrocytic ": 90.36771396112262, "Anaemia megaloblastic ": 39.07619223461191, "Anaemia neonatal ": 53.43388190337051, "Anal atresia ": 36.07291863631076, "Anencephaly ": 46.60903777122272, "Angina unstable ": 5.191448261231964, "Anogenital warts ": 37.16774233533396, "Aplasia pure red cell ": 5.211683537367236, "Aplastic anaemia ": 8.483671029155875, "Appendicectomy ": 44.60740897940171, "Arteriosclerosis coronary artery ": 3.210630654223092, "Ascites ": 2.9933114466888284, "Aspartate aminotransferase increased ": 4.403588150559111, "Atrial flutter ": 3.15522514227467, "Atrial septal defect ": 10.796677835076316, "Attention deficit hyperactivity disorder ": 3.8574475549439966, "Blood bilirubin increased ": 5.720541165596119, "Blood creatine phosphokinase increased ": 2.7927875189024887, "Blood lactate dehydrogenase increased ": 4.3035728758008736, "Blood lactic acid increased ": 15.868558367731406, "Blood triglycerides increased ": 2.562798702562856, "Bone marrow failure ": 3.226146820815454, "Brain herniation ": 20.24134123754979, "CD4 lymphocytes decreased ": 40.86046940252768, "Caesarean section ": 27.38231212110665, "Cardiac murmur ": 16.44928080986794, "Cellulitis ": 2.235234738745988, "Cerebellar hypoplasia ": 84.8471967157688, "Cholangitis ": 6.734371444184069, "Cholecystitis ": 4.319460760248536, "Cholestasis ": 2.945362665321805, "Chronic inflammatory demyelinating polyradiculoneuropathy ": 9.845456742801852, "Chronic sinusitis ": 8.872108752399962, "Cleft palate ": 30.021965792978182, "Congenital anomaly ": 18.19216385537997, "Congenital aplasia ": 11.70018866826262, "Congenital central nervous system anomaly ": 54.60220120505437, "Congenital choroid plexus cyst ": 104.51399542322108, "Congenital diaphragmatic hernia ": 51.97426602649128, "Congenital hydrocephalus ": 97.75788308783716, "Congenital hydronephrosis ": 91.38563586304085, "Corneal opacity ": 15.354564899313944, "Cryptorchism ": 27.51490976451842, "Cyst ": 4.001906726626326, "Cytomegalovirus chorioretinitis ": 24.145635615040327, "Cytomegalovirus infection ": 2.597041743714282, "Dandy-Walker syndrome ": 87.95008923313456, "Death neonatal ": 20.711876675652128, "Delivery ": 19.34553140544672, "Depressive symptom ": 3.140711009756534, "Developmental delay ": 3.5691232798661567, "Dry throat ": 2.482897451961384, "Dyslipidaemia ": 11.310499689645104, "Dysmorphism ": 8.129044492437178, "Ear malformation ": 41.75491384864407, "Echocardiogram abnormal ": 14.1774643664846, "Electrocardiogram abnormal ": 2.6318488674283325, "Electroencephalogram abnormal ": 11.393316842986644, "Encephalocele ": 122.76418322146375, "Eosinophilia ": 2.550146602546409, "Exophthalmos ": 26.24100695540829, "Exposure during pregnancy ": 8.405629053570104, "Fat redistribution ": 72.58966387499866, "Fat tissue increased ": 19.774919774494677, "Foetal death ": 11.808092646693671, "Foetal distress syndrome ": 31.476179164783108, "Foetal exposure during pregnancy ": 15.014643266201118, "Foetal growth restriction ": 15.135765488134268, "Foetal malformation ": 19.24237843004301, "Folate deficiency ": 38.79745520228781, "Foot deformity ": 5.03464370043909, "Gestational diabetes ": 17.74221502584702, "Gestational hypertension ": 24.861693204686684, "Granulocytopenia ": 5.003781314045828, "Graves' disease ": 3.986201971449111, "Gynaecomastia ": 3.2681477364346936, "HIV-associated neurocognitive disorder ": 50.75525594379243, "Haemoglobin decreased ": 3.121522919912244, "Haemolytic anaemia ": 7.7129316927656975, "Haptoglobin decreased ": 20.665057068757665, "Heart disease congenital ": 5.062314841351838, "Hepatic cytolysis ": 4.044839150019739, "Hepatic enzyme increased ": 2.724196635579134, "Hepatic failure ": 2.803573999074436, "Hepatic fibrosis ": 8.088944048381823, "Hepatic steatosis ": 5.560928095815048, "Hepatitis ": 5.510310798753819, "Hepatitis B ": 9.94832876686307, "Hepatitis acute ": 2.4135491630461425, "Hepatosplenomegaly ": 9.84831592481146, "Hepatotoxicity ": 4.078806108719815, "Herpes virus infection ": 3.960215327357408, "Hip surgery ": 29.4247876783338, "Hydrocephalus ": 11.704667221039369, "Hydronephrosis ": 10.746430210204553, "Hydrops foetalis ": 36.51244653979159, "Hyperbilirubinaemia ": 9.644926517629614, "Hypercholesterolaemia ": 4.236795279306797, "Hyperchromic anaemia ": 185.9864470141101, "Hyperlactacidaemia ": 10.32615128872965, "Hyperlipidaemia ": 4.525457452996397, "Hypertonia ": 3.0766469571252038, "Hypertriglyceridaemia ": 22.572677471226296, "Hyperuricaemia ": 5.458660354075048, "Hypocalcaemia ": 3.449456698593633, "Hypophosphataemia ": 4.32014210436532, "Hypotonia ": 3.1492794709685703, "Immune reconstitution inflammatory syndrome ": 12.806362652213348, "Inguinal hernia ": 5.414505842323663, "Intellectual disability ": 5.824935971387321, "Jaundice ": 7.379535794035868, "Jaundice neonatal ": 7.267834109154724, "Kaposi's sarcoma ": 26.95667750797016, "Keratopathy ": 32.03417284330178, "Laboratory test abnormal ": 3.758538240824844, "Lactic acidosis ": 4.102785800585461, "Leukopenia ": 2.798437651650655, "Lip discolouration ": 26.47207259420638, "Lipase increased ": 3.386938801884705, "Lipids abnormal ": 24.880789245241147, "Lipoatrophy ": 18.59625241056286, "Lipodystrophy acquired ": 121.14353686676807, "Live birth ": 17.159039974943088, "Liver function test abnormal ": 5.160906144476018, "Low birth weight baby ": 4.569809732683283, "Low set ears ": 55.48362368470901, "Lymphadenitis ": 3.043925803844411, "Macrocytosis ": 26.695846554904747, "Malaria ": 60.12535236189317, "Maternal exposure during pregnancy ": 2.6424769547444047, "Maternal exposure timing unspecified ": 27.75796375603813, "Meconium in amniotic fluid ": 41.224156739232924, "Meningitis tuberculous ": 29.838379456352666, "Meningomyelocele ": 53.79285941713882, "Microcephaly ": 14.905457190049656, "Microcytosis ": 171.16376157047154, "Mitochondrial cytopathy ": 52.83260521541753, "Monoplegia ": 3.015751250058257, "Multiple-drug resistance ": 8.138254552665765, "Myopathy ": 3.215027357134657, "Nail discolouration ": 8.117974909087486, "Nephrolithiasis ": 2.056012805956021, "Nerve injury ": 2.093061644280116, "Neural tube defect ": 54.92696561304764, "Neutropenia ": 2.909324939063025, "Non-Hodgkin's lymphoma ": 5.592901672522456, "Normal newborn ": 40.04443202687385, "Oesophageal ulcer ": 6.6332895650558505, "Oligohydramnios ": 10.299848992273906, "Optic nerve disorder ": 15.585757400271092, "Optic neuritis ": 4.191856692675621, "Optic neuropathy ": 11.184288860664696, "Otitis media ": 7.929004504899535, "Pallor ": 2.710531658381941, "Pancreatic failure ": 56.3254648398669, "Pancreatitis acute ": 2.146778328158112, "Pancytopenia ": 6.285346772838557, "Papilloma ": 118.6214886852543, "Patent ductus arteriosus ": 8.213741271929631, "Pathogen resistance ": 2.996309201601516, "Pharyngitis ": 2.109159832113177, "Placental disorder ": 24.546871304112383, "Plasmablastic lymphoma ": 71.219658842243, "Pneumocystis jirovecii pneumonia ": 4.627442006135585, "Polydactyly ": 95.8083307570583, "Polypectomy ": 139.53448020130247, "Pre-eclampsia ": 7.103361370899588, "Pregnancy ": 36.05845446688756, "Premature baby ": 17.031251404823326, "Premature delivery ": 10.8441398054403, "Premature labour ": 13.47592596315812, "Premature rupture of membranes ": 31.29985680412729, "Prothrombin level decreased ": 8.294196364349702, "Pulmonary tuberculosis ": 9.36722900056363, "Pyelocaliectasis ": 24.966858157739416, "Pyelonephritis ": 6.442216334082375, "Rash maculo-papular ": 2.9336086999229494, "Red blood cell abnormality ": 24.448978223515923, "Renal colic ": 8.644779808125227, "Sinusitis ": 2.298957535510994, "Speech disorder developmental ": 6.2945091065344405, "Spina bifida ": 28.548484528546588, "Spinal fusion surgery ": 47.60456060859282, "Spinocerebellar disorder ": 518.9109229694644, "Splenomegaly ": 4.313373918308522, "Stevens-Johnson syndrome ": 4.075784392133059, "Stillbirth ": 57.30267273245861, "Talipes ": 30.08190886333052, "Thrombocytopenia neonatal ": 73.11391863051134, "Torsade de pointes ": 2.3804226744105392, "Toxic skin eruption ": 2.098781724794677, "Transaminases increased ": 2.4845407021183474, "Treatment noncompliance ": 3.42792753702361, "Trisomy 21 ": 67.38625597794434, "Tuberculosis ": 7.817686107574019, "Ultrasound kidney abnormal ": 191.76965600620247, "Underweight ": 15.18238783912946, "Ventricular septal defect ": 5.457577702051131, "Viral load decreased ": 237.65736056839475, "Viral load increased ": 7.794316609638822, "Viral mutation identified ": 13.018284079113114, "Virologic failure ": 7.704339649386891, "Visual acuity reduced ": 2.0797661191021044, "Visual field defect ": 3.154701654509358}
\ No newline at end of file
+{"Cerebrovascular accident": 77.26428973559938, "Confusional state": 36.001778756256506, "Death": 5.762492945999524, "Disorientation": 151.6179261085339, "Speech disorder": 145.40084618508902}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/286.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/286.json
index b139fc5f3d8..3952ef0c1a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/286.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/286.json
@@ -1 +1 @@
-{"Abdominal pain lower ": 2.2912591100450763, "Abnormal menstrual clots ": 4.610774565666639, "Abnormal uterine bleeding ": 2.8367571727452314, "Abnormal withdrawal bleeding ": 7.039855133367335, "Acute aseptic arthritis ": 3.454785090503722, "Acute polyneuropathy ": 2.353703880402512, "Acute stress disorder ": 3.9481615494290017, "Acute vestibular syndrome ": 6.211514709348975, "Adenomyosis ": 4.246909728886785, "Administration site erythema ": 4.903241374154537, "Administration site joint pain ": 4.613036758058735, "Administration site lymphadenopathy ": 4.387298973774572, "Administration site movement impairment ": 4.426035853573776, "Administration site oedema ": 9.27841672303305, "Administration site pain ": 10.807532311765884, "Administration site paraesthesia ": 3.734276723501122, "Administration site reaction ": 4.840036543297722, "Adnexa uteri pain ": 6.486851146192079, "Adrenocortical steroid therapy ": 3.870258053096293, "Allergy to arthropod sting ": 2.0804350432753664, "Alopecia areata ": 2.270664624973621, "Amenorrhoea ": 12.423260167497116, "Anaesthesia ": 5.957808206726362, "Anosmia ": 2.4111440495695606, "Anovulatory cycle ": 9.018223918948843, "Anti-thyroid antibody increased ": 4.343951402358383, "Antibody-dependent enhancement ": 7.484139599408403, "Application site hypoaesthesia ": 3.5231563466910822, "Application site lymphadenopathy ": 11.401112698468564, "Application site movement impairment ": 5.827157835572923, "Application site swelling ": 2.016873632289655, "Arrhythmia ": 2.7896177426539377, "Arthralgia ": 2.3975398424383667, "Arthritis reactive ": 2.9583985515168583, "Autoantibody positive ": 4.6386364769013095, "Autoantibody test ": 4.298638432552899, "Autoimmune myositis ": 2.722567538945547, "Axillary lymphadenectomy ": 2.1900734129944857, "Axillary mass ": 4.831571464584694, "Axillary pain ": 7.516416794400517, "Axonal and demyelinating polyneuropathy ": 2.57867857852947, "Basilar artery thrombosis ": 2.831725534817686, "Bell's palsy ": 2.7804679281392986, "Body temperature increased ": 2.432804654573451, "Breakthrough COVID-19 ": 4.009885461607158, "Breast discomfort ": 3.147472992979781, "Breast engorgement ": 6.233782305272988, "Breast enlargement ": 3.351256566633026, "Breast inflammation ": 6.41050713918413, "Breast oedema ": 5.882816660105015, "Breast pain ": 4.408366062322136, "Breast swelling ": 5.213203589977337, "Breast tenderness ": 3.996406142481152, "COVID-19 ": 8.211410280255809, "COVID-19 immunisation ": 4.746335166090454, "COVID-19 pneumonia ": 2.057750211588409, "Capillary fragility ": 2.7819568356795674, "Cardiac discomfort ": 4.978901487778691, "Cardiovascular deconditioning ": 5.133015970635388, "Cardiovascular symptom ": 2.4455259787017978, "Carditis ": 4.956730160555961, "Caregiver ": 5.05061219477771, "Carotid artery dissection ": 3.091901208942295, "Carotid pulse increased ": 3.848447421051007, "Cervicobrachial syndrome ": 3.553588392658761, "Chest discomfort ": 2.172128506329042, "Chest pain ": 2.0014027741041254, "Chillblains ": 3.6256722447224736, "Chills ": 2.2684483213341604, "Chronic fatigue syndrome ": 4.591700454870085, "Chronic idiopathic pain syndrome ": 2.639632555237601, "Circumoral swelling ": 2.855414752375806, "Clinically isolated syndrome ": 2.7311374751197177, "Coital bleeding ": 4.74749618218401, "Cold urticaria ": 2.425283125648158, "Concomitant drug effect decreased ": 3.2939374752118877, "Costochondritis ": 2.1124367550227974, "Cramp-fasciculation syndrome ": 3.80291233442616, "Creutzfeldt-Jakob disease ": 2.312765144319058, "Cystitis noninfective ": 3.914604353285155, "Dengue virus test positive ": 6.732630193117614, "Dermal filler reaction ": 2.556611710984971, "Diaphragmalgia ": 2.2810738365682446, "Disturbance in attention ": 2.06469187703172, "Dysaesthesia ": 3.0784989660561908, "Dysmenorrhoea ": 10.7953701791866, "Ear discomfort ": 2.688286132300856, "Ear inflammation ": 3.947872624508932, "Electrocardiogram PR segment depression ": 6.398561737497216, "Endometriosis ": 3.13651424548092, "Endothelial dysfunction ": 2.554716458727643, "Enhanced respiratory disease ": 5.826477930954527, "Exercise tolerance decreased ": 3.824257425760282, "Exertional headache ": 2.276571794604867, "Extensive swelling of vaccinated limb ": 3.87458736113978, "Extrasystoles ": 2.657279370850107, "Eye haematoma ": 2.272357017338263, "Eye infarction ": 4.901815099408192, "Eye paraesthesia ": 2.512606360107472, "Eyelid haematoma ": 2.2035220165062155, "Eyelid myokymia ": 8.311033944431344, "Facial asymmetry ": 2.032958747477779, "Facial discomfort ": 3.521024837746995, "Facial myokymia ": 6.407483561201405, "Facial nerve disorder ": 2.382157763727566, "Facial paralysis ": 3.669167530961314, "Facial paresis ": 4.797193433870077, "Fatigue ": 2.5862572664641355, "Feeling hot ": 2.713598352262641, "Feeling of body temperature change ": 2.197930317318467, "Fibrin D dimer increased ": 2.799785467472632, "Galactostasis ": 6.216119076216367, "Genital herpes ": 2.668360842875378, "Genital pain ": 2.033515955780333, "Giant cell arteritis ": 2.3283909617517726, "Haemorrhoids thrombosed ": 2.0101434360554293, "Hand dermatitis ": 2.3111801825308653, "Head discomfort ": 2.037629200056689, "Headache ": 2.6377812993112717, "Heart rate variability decreased ": 2.6759737890019, "Heart rate variability increased ": 4.366177200445366, "Heavy menstrual bleeding ": 9.841936438014638, "Hemianaesthesia ": 6.830589123450165, "Hemiataxia ": 2.0402453882154927, "Hemidysaesthesia ": 7.861926840932619, "Hemihyperaesthesia ": 4.84615206062194, "Hemihypoaesthesia ": 8.324923275330095, "Hemiparaesthesia ": 7.000938039619148, "Herpes simplex reactivation ": 2.955895917989765, "Herpes zoster ": 2.243090055306674, "Herpes zoster reactivation ": 2.2601676613157653, "Histamine abnormal ": 2.5861358106910566, "Histamine intolerance ": 4.241330605731263, "Hormone level abnormal ": 3.5060051168511563, "Hyperacusis ": 2.116839263761337, "Hyperaesthesia ": 2.0332315962782808, "Hyperresponsive to stimuli ": 5.196563295091902, "Hypoaesthesia ": 2.276074217052864, "Hypoaesthesia oral ": 2.074327469183596, "Hypomenorrhoea ": 9.508405574782818, "Immunisation ": 48.83361139688855, "Immunisation reaction ": 7.256999281558455, "Immunisation stress-related response ": 6.688910052273217, "Infection susceptibility increased ": 3.325213944130507, "Influenza like illness ": 2.410989598794739, "Injected limb mobility decreased ": 5.63747618979328, "Injection site discomfort ": 2.468223417533542, "Injection site erythema ": 2.154836137268935, "Injection site haematoma ": 3.863586254258995, "Injection site hypoaesthesia ": 3.279454823176971, "Injection site inflammation ": 3.541512045035942, "Injection site joint movement impairment ": 4.773549034603106, "Injection site joint pain ": 2.0185577449333847, "Injection site lymphadenopathy ": 7.570753144330452, "Injection site movement impairment ": 4.000425876547105, "Injection site muscle weakness ": 6.078971809531408, "Injection site oedema ": 2.798774516405392, "Injection site pain ": 4.142683309206558, "Injection site paraesthesia ": 3.068697257100028, "Injection site reaction ": 2.805189104071823, "Injection site swelling ": 3.311375266317887, "Injection site warmth ": 3.2894829813855164, "Interchange of vaccine products ": 21.00655705913473, "Intercostal neuralgia ": 2.692380184403124, "Interferon gamma decreased ": 4.287974352894451, "Interleukin level decreased ": 5.33278085778676, "Intermenstrual bleeding ": 11.099753728844435, "Intestinal barrier dysfunction ": 5.3119641784435485, "Intrauterine contraception ": 7.907296974613479, "Labour pain ": 4.22588558148384, "Lactation disorder ": 2.982256622721679, "Lactation insufficiency ": 6.564920227755662, "Lactation puerperal increased ": 2.7595088998447697, "Laryngeal inflammation ": 2.350955373176944, "Lichen planopilaris ": 2.743845232190221, "Lichen sclerosus ": 2.2413257631804453, "Limb discomfort ": 3.785311125001844, "Lip pruritus ": 2.1272476942727536, "Local reaction ": 2.3585392090681263, "Localised oedema ": 2.1538551058949587, "Loefgren syndrome ": 2.526008366242428, "Lymph node abscess ": 2.034326152502664, "Lymph node pain ": 8.075901685742306, "Lymph node palpable ": 3.726739073197198, "Lymphadenitis ": 7.142222861389564, "Lymphadenopathy ": 7.478022544050123, "Malaise ": 2.6422687249103607, "Mast cell activation syndrome ": 2.404794010561785, "Mastitis ": 2.783125266355148, "Mastitis postpartum ": 11.228648755461542, "Menarche ": 11.58258423488003, "Menometrorrhagia ": 14.867551134262436, "Menstrual clots ": 2.66829793192535, "Menstrual cycle management ": 16.876233111511485, "Menstrual discomfort ": 20.68434401105291, "Menstrual disorder ": 15.235498210707116, "Menstrual headache ": 7.097310558455764, "Menstruation delayed ": 8.3983681665545, "Menstruation irregular ": 10.921590720679024, "Menstruation normal ": 2.7592193060025574, "Migraine with aura ": 2.3141641579140586, "Miller Fisher syndrome ": 2.213068882010747, "Monoparesis ": 2.4788084943555684, "Multisystem inflammatory syndrome ": 2.2910237437353307, "Multisystem inflammatory syndrome in adults ": 2.5915127334107493, "Multisystem inflammatory syndrome in children ": 4.895190768110581, "Muscle strength abnormal ": 2.220914997034065, "Musculoskeletal pain ": 2.1239748392696964, "Myalgia ": 3.426081177760506, "Myalgia intercostal ": 3.755795029612401, "Myelitis ": 3.0083303713832867, "Myocarditis ": 6.197062538509944, "Myokymia ": 7.658790384145563, "Myopericarditis ": 5.3983231716635975, "Nasal herpes ": 3.026368624942601, "Nasal vestibulitis ": 3.616081865482766, "Neck pain ": 2.061385954454366, "Neuralgia ": 2.7076202161824394, "Neuralgic amyotrophy ": 5.649980460817649, "Neuritis ": 2.0918669950175723, "Neurodermatitis ": 2.978623963247665, "Neuromuscular pain ": 2.265036149485321, "New daily persistent headache ": 3.0279954715369333, "Noninfective oophoritis ": 2.7552060383857886, "Nuchal rigidity ": 2.265487973017836, "Occipital neuralgia ": 2.074971587369053, "Oligomenorrhoea ": 17.332305685473493, "Omental infarction ": 2.146884941059276, "Ophthalmic artery occlusion ": 3.2178071789352845, "Ophthalmic artery thrombosis ": 2.146884941059276, "Ophthalmic migraine ": 2.801471198401816, "Ophthalmic vascular thrombosis ": 2.1418821255626903, "Ophthalmic vein thrombosis ": 5.125084534539589, "Oral contraception ": 8.441672520054388, "Oral herpes ": 2.390073072406059, "Oropharyngeal discomfort ": 2.779290323216589, "Ovulation delayed ": 11.453165702058676, "Ovulation disorder ": 9.183405092974358, "Ovulation pain ": 9.93563583106262, "Pain in extremity ": 2.5356407742444707, "Painful respiration ": 3.026459956159598, "Palpitations ": 2.43251858542271, "Paraesthesia ": 3.043902393474709, "Paraesthesia oral ": 2.0204853071541984, "Parosmia ": 2.152650668184402, "Pelvic pain ": 2.5150598844836654, "Performance status decreased ": 3.242313946243213, "Periarthritis ": 2.468570430037872, "Pericardial fibrosis ": 2.691300251014165, "Pericarditis ": 4.70852925776631, "Perichondritis ": 2.687666997909171, "Periorbital discomfort ": 2.1620430088028515, "Peripheral circulatory failure ": 2.2206821637244043, "Peripheral nerve paresis ": 2.5915127334107493, "Pernio-like erythema ": 3.606310516070311, "Pharyngeal paraesthesia ": 2.2457231029240674, "Phobic postural vertigo ": 5.832993491151451, "Pityriasis rosea ": 5.87389143338205, "Polymenorrhagia ": 5.466745188948011, "Polymenorrhoea ": 16.14731686872899, "Polymers allergy ": 2.464852379631598, "Polymyalgia rheumatica ": 3.9922588888628496, "Poor milk ejection reflex ": 5.55088874642594, "Post vaccination syndrome ": 13.416230219233356, "Post-acute COVID-19 syndrome ": 8.180331892970766, "Postmenopausal haemorrhage ": 5.847274064745463, "Postural orthostatic tachycardia syndrome ": 2.6349018986793893, "Pre-existing disease ": 2.9396643527144874, "Pregnancy test negative ": 4.585949489481648, "Premature ovulation ": 4.484089432891292, "Premenstrual dysphoric disorder ": 3.786163247309833, "Premenstrual headache ": 4.660515762898247, "Premenstrual pain ": 8.717170755048063, "Premenstrual syndrome ": 11.47569156296703, "Presyncope ": 2.4906942225785835, "Pulmonary pain ": 2.88929836282156, "Pulse volume decreased ": 2.799662579195312, "Puncture site erythema ": 2.4105878439243185, "Puncture site oedema ": 6.989963951316693, "Puncture site pain ": 9.072289467127945, "Puncture site pruritus ": 5.196563295091902, "Puncture site reaction ": 4.017291734526552, "Puncture site swelling ": 2.1389082728335675, "Rest regimen ": 2.1053360165839483, "Reversed hot-cold sensation ": 2.6927479425134058, "Rheumatic disorder ": 2.89711670611894, "SARS-CoV-2 antibody test ": 2.6320423619467888, "SARS-CoV-2 antibody test negative ": 10.37341959112922, "SARS-CoV-2 antibody test positive ": 3.4412560137489514, "SARS-CoV-2 test negative ": 3.2521150262284872, "SARS-CoV-2 test positive ": 4.549785725458658, "Sacroiliac joint dysfunction ": 2.5861358106910566, "Scar discomfort ": 6.927205357891813, "Scar inflammation ": 2.359810902191282, "Sensory disturbance ": 2.0476264854854485, "Sensory level abnormal ": 5.669066257379607, "Sensory overload ": 2.5271921094498424, "Shoulder injury related to vaccine administration ": 3.866225327317989, "Sick leave ": 9.59012983394286, "Skin discomfort ": 2.635025098748173, "Small fibre neuropathy ": 4.125506436121609, "Soft tissue swelling ": 2.100855142256637, "Specialist consultation ": 4.997727888674078, "Spider vein ": 2.1194834023214177, "Sudden hearing loss ": 3.4762712786651027, "Superficial vein thrombosis ": 2.68814148709798, "Supraclavicular fossa pain ": 7.565839499100232, "Suspected COVID-19 ": 5.208293030269041, "Tachycardia ": 2.1664008122180958, "Temperature perception test increased ": 3.092420740037095, "Tendon sheath disorder ": 2.579137776981064, "Thalamic infarction ": 2.098663923536052, "Thyroid pain ": 2.6756148219467577, "Thyroiditis acute ": 2.185505935000232, "Thyroiditis subacute ": 3.193878693232928, "Tinnitus ": 2.4262952268732096, "Tonsillar inflammation ": 2.1904942706014165, "Trigeminal nerve disorder ": 3.0359851947470227, "Trigeminal nerve paresis ": 3.058257117440734, "Trigeminal neuralgia ": 3.029832610545223, "Trigeminal neuritis ": 4.41111651378941, "Trigeminal neuropathy ": 2.4529419997878774, "Troponin ": 2.163403891896227, "Troponin abnormal ": 5.508295369867352, "Troponin increased ": 2.080719252215529, "Unexpected vaginal bleeding on hormonal IUD ": 6.407483561201405, "Urticaria chronic ": 2.3892183203417794, "Uterine inflammation ": 3.0441404208734646, "Uterine pain ": 8.087864480267562, "Uterine spasm ": 4.570349250029271, "Uterine tenderness ": 2.968059819743332, "Vaccination failure ": 10.741579880837469, "Vaccination site anaesthesia ": 2.426729076150728, "Vaccination site atrophy ": 2.1804213082970065, "Vaccination site bruising ": 3.302135301115764, "Vaccination site coldness ": 2.855865068510885, "Vaccination site discharge ": 2.063812368345737, "Vaccination site discolouration ": 2.3572455723294583, "Vaccination site discomfort ": 2.416801000324359, "Vaccination site dysaesthesia ": 5.025671607600538, "Vaccination site erythema ": 4.2829443320332015, "Vaccination site haematoma ": 4.889528872062062, "Vaccination site haemorrhage ": 4.340562251392951, "Vaccination site hyperaesthesia ": 5.635636730344197, "Vaccination site hypersensitivity ": 2.527049262696335, "Vaccination site hypoaesthesia ": 6.890849864038543, "Vaccination site induration ": 3.6868934586111, "Vaccination site inflammation ": 2.993634786888085, "Vaccination site injury ": 2.770746747398023, "Vaccination site joint discomfort ": 2.146884941059276, "Vaccination site joint erythema ": 3.2465589936346686, "Vaccination site joint inflammation ": 6.150080386265568, "Vaccination site joint movement impairment ": 4.5454169849558825, "Vaccination site joint pain ": 5.350382344891142, "Vaccination site joint swelling ": 4.685275853762176, "Vaccination site lymphadenopathy ": 11.956001955204387, "Vaccination site mass ": 2.4822635967342523, "Vaccination site movement impairment ": 5.17644447538072, "Vaccination site necrosis ": 3.851190703815121, "Vaccination site nerve damage ": 4.687358057553326, "Vaccination site nodule ": 2.138038671763361, "Vaccination site oedema ": 5.873642047094477, "Vaccination site pain ": 6.947657335236569, "Vaccination site paraesthesia ": 7.746249301463012, "Vaccination site pruritus ": 5.517383901157182, "Vaccination site reaction ": 4.016720724803783, "Vaccination site scab ": 2.347258077801965, "Vaccination site scar ": 2.280201205703236, "Vaccination site swelling ": 4.960439116185119, "Vaccination site thrombosis ": 4.2791271038711365, "Vaccination site ulcer ": 3.569297145616372, "Vaccination site urticaria ": 2.2097876373299057, "Vaccination site warmth ": 2.805225226235806, "Vaccine breakthrough infection ": 3.0333519683017856, "Varicophlebitis ": 2.27748777267244, "Vascular pain ": 2.1339417027539027, "Venous thrombosis limb ": 3.172521138280369, "Vertebral artery dissection ": 2.6995265656087755, "Vertebrobasilar stroke ": 2.046638415200725, "Vertigo positional ": 2.937412103383491, "Vestibular neuronitis ": 5.668415775293667, "Weight bearing difficulty ": 6.141551440653261}
\ No newline at end of file
+{"Acute kidney injury": 18.00772595547702, "Blood creatinine increased": 4.721646151499575, "Drug ineffective": 2.629417334182547, "Drug interaction": 2.641293372751392, "Klebsiella infection": 171.0713704104597, "Muscular weakness": 3.946657388586083, "Neurotoxicity": 38.40526030714968, "Overdose": 3.398565002869733, "Pathogen resistance": 60.92862420526939, "Vertigo": 4.081051256129409}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/287.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/287.json
index 1ff631ec6ca..a064a6aa8e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/287.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/287.json
@@ -1 +1 @@
-{"Acute kidney injury ": 8.674211108635001, "Hypoglycaemia ": 52.72942209775195, "Lactic acidosis ": 78.00036413067367}
\ No newline at end of file
+{"Contusion": 32.22100194002236, "Dupuytren's contracture": 3283.2422052339657, "Incorrect dose administered": 26.17725192161104, "Oedema peripheral": 33.28489801270281, "Skin laceration": 564.5997339138858, "Tendon rupture": 179.28475633377508}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/288.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/288.json
index 6ec106e2b22..3a88500fe03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/288.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/288.json
@@ -1 +1 @@
-{"Eosinophilia ": 41.24530569511127, "Gamma-glutamyltransferase increased ": 16.21460878059043, "Hepatic cytolysis ": 48.42793068909916, "Hepatic function abnormal ": 9.63094524108071, "Insomnia ": 3.4531784156906857, "Oedema ": 12.91950466584628, "Skin exfoliation ": 22.56718752593687, "Suspected counterfeit product ": 408.5722481012281, "Weight decreased ": 3.5865896688447374}
\ No newline at end of file
+{"Cough": 19.742800973368336, "Death": 3.7444808560178986, "Dyspnoea": 3.004902763503478, "Haemoptysis": 26.677273143342997, "Off label use": 3.560276079488572, "Pneumonia": 4.677916912542848, "Product physical issue": 173.9784084673403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/289.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/289.json
index 95d383770af..aee8d7b90d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/289.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/289.json
@@ -1 +1 @@
-{"Chills ": 11.469155183502448}
\ No newline at end of file
+{"Abdominal distension": 2.1397018103290275, "Abnormal dreams": 2.402627690194404, "Abortion induced": 20.807068118388536, "Abortion missed": 15.92037670770376, "Abortion spontaneous": 7.264560865183492, "Acquired gene mutation": 24.0434142335154, "Acute pulmonary oedema": 3.1330727746349, "Adenotonsillectomy": 477.097705543272, "Adrenogenital syndrome": 240.005173795878, "Adverse reaction": 2.0468256303664703, "Alanine aminotransferase increased": 4.1011758723239495, "Alpha 1 foetoprotein abnormal": 229.0867695823449, "Alpha 1 foetoprotein increased": 21.752127181864463, "Ammonia increased": 3.869856930423088, "Amylase increased": 3.834942172549373, "Anaemia": 8.90731609033329, "Anaemia macrocytic": 90.36771396112262, "Anaemia megaloblastic": 39.07619223461191, "Anaemia neonatal": 53.43388190337051, "Anal atresia": 36.07291863631076, "Anencephaly": 46.60903777122272, "Angina unstable": 5.191448261231964, "Anogenital warts": 37.16774233533396, "Aplasia pure red cell": 5.211683537367236, "Aplastic anaemia": 8.483671029155875, "Appendicectomy": 44.60740897940171, "Arteriosclerosis coronary artery": 3.210630654223092, "Ascites": 2.9933114466888284, "Aspartate aminotransferase increased": 4.403588150559111, "Atrial flutter": 3.15522514227467, "Atrial septal defect": 10.796677835076316, "Attention deficit hyperactivity disorder": 3.8574475549439966, "Blood bilirubin increased": 5.720541165596119, "Blood creatine phosphokinase increased": 2.7927875189024887, "Blood lactate dehydrogenase increased": 4.3035728758008736, "Blood lactic acid increased": 15.868558367731406, "Blood triglycerides increased": 2.562798702562856, "Bone marrow failure": 3.226146820815454, "Brain herniation": 20.24134123754979, "CD4 lymphocytes decreased": 40.86046940252768, "Caesarean section": 27.38231212110665, "Cardiac murmur": 16.44928080986794, "Cellulitis": 2.235234738745988, "Cerebellar hypoplasia": 84.8471967157688, "Cholangitis": 6.734371444184069, "Cholecystitis": 4.319460760248536, "Cholestasis": 2.945362665321805, "Chronic inflammatory demyelinating polyradiculoneuropathy": 9.845456742801852, "Chronic sinusitis": 8.872108752399962, "Cleft palate": 30.021965792978182, "Congenital anomaly": 18.19216385537997, "Congenital aplasia": 11.663382328062069, "Congenital central nervous system anomaly": 54.60220120505437, "Congenital choroid plexus cyst": 104.51399542322108, "Congenital diaphragmatic hernia": 51.97426602649128, "Congenital hydrocephalus": 97.75788308783716, "Congenital hydronephrosis": 91.38563586304085, "Corneal opacity": 15.354564899313944, "Cryptorchism": 27.51490976451842, "Cyst": 4.001906726626326, "Cytomegalovirus chorioretinitis": 24.145635615040327, "Cytomegalovirus infection": 2.597041743714282, "Dandy-Walker syndrome": 87.95008923313456, "Death neonatal": 20.711876675652128, "Delivery": 19.34553140544672, "Depressive symptom": 3.140711009756534, "Developmental delay": 3.5677303928096813, "Dry throat": 2.482897451961384, 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10.32615128872965, "Hyperlipidaemia": 4.525457452996397, "Hypertonia": 3.0766469571252038, "Hypertriglyceridaemia": 22.572677471226296, "Hyperuricaemia": 5.458660354075048, "Hypocalcaemia": 3.449456698593633, "Hypophosphataemia": 4.32014210436532, "Hypotonia": 3.1489404178673763, "Immune reconstitution inflammatory syndrome": 12.806362652213348, "Inguinal hernia": 5.414505842323663, "Intellectual disability": 5.824935971387321, "Jaundice": 7.379535794035868, "Jaundice neonatal": 7.267834109154724, "Kaposi's sarcoma": 26.95667750797016, "Keratopathy": 32.03417284330178, "Laboratory test abnormal": 3.758538240824844, "Lactic acidosis": 4.102785800585461, "Leukopenia": 2.7980842118666978, "Lip discolouration": 26.47207259420638, "Lipase increased": 3.386938801884705, "Lipids abnormal": 24.880789245241147, "Lipoatrophy": 18.59625241056286, "Lipodystrophy acquired": 121.14353686676807, "Live birth": 17.159039974943088, "Liver function test abnormal": 5.160906144476018, "Low birth weight 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"Optic nerve disorder": 15.585757400271092, "Optic neuritis": 4.191856692675621, "Optic neuropathy": 11.184288860664696, "Otitis media": 7.929004504899535, "Pallor": 2.710359958251447, "Pancreatic failure": 56.3254648398669, "Pancreatitis acute": 2.146778328158112, "Pancytopenia": 6.285346772838557, "Papilloma": 118.6214886852543, "Patent ductus arteriosus": 8.213741271929631, "Pathogen resistance": 2.996309201601516, "Pharyngitis": 2.108673334253926, "Placental disorder": 24.546871304112383, "Plasmablastic lymphoma": 71.219658842243, "Pneumocystis jirovecii pneumonia": 4.627442006135585, "Polydactyly": 95.8083307570583, "Polypectomy": 139.53448020130247, "Pre-eclampsia": 7.103361370899588, "Pregnancy": 36.05845446688756, "Premature baby": 17.031251404823326, "Premature delivery": 10.8441398054403, "Premature labour": 13.47592596315812, "Premature rupture of membranes": 31.29985680412729, "Prothrombin level decreased": 8.294196364349702, "Pulmonary tuberculosis": 9.36722900056363, "Pyelocaliectasis": 24.966858157739416, "Pyelonephritis": 6.442216334082375, "Rash maculo-papular": 2.9336086999229494, "Red blood cell abnormality": 24.448978223515923, "Renal colic": 8.644779808125227, "Sinusitis": 2.298957535510994, "Speech disorder developmental": 6.2945091065344405, "Spina bifida": 28.548484528546588, "Spinal fusion surgery": 47.60456060859282, "Spinocerebellar disorder": 518.9109229694644, "Splenomegaly": 4.313373918308522, "Stevens-Johnson syndrome": 4.075784392133059, "Stillbirth": 57.30267273245861, "Talipes": 30.08190886333052, "Thrombocytopenia neonatal": 73.11391863051134, "Torsade de pointes": 2.3804226744105392, "Toxic skin eruption": 2.098781724794677, "Transaminases increased": 2.484388306940845, "Treatment noncompliance": 3.42792753702361, "Trisomy 21": 67.38625597794434, "Tuberculosis": 7.817686107574019, "Ultrasound kidney abnormal": 191.76965600620247, "Underweight": 15.18238783912946, "Ventricular septal defect": 5.457577702051131, "Viral load decreased": 237.65736056839475, "Viral load increased": 7.794316609638822, "Viral mutation identified": 13.018284079113114, "Virologic failure": 7.704339649386891, "Visual acuity reduced": 2.0797661191021044, "Visual field defect": 3.154701654509358}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/29.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/29.json
index 43820c2012e..3f364aef17d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/29.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/29.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.095731150133332, "Abdominal distension ": 4.511819407257338, "Acute respiratory failure ": 3.2624012654356576, "Ascites ": 2.994572045662028, "Blood potassium decreased ": 3.204998557492243, "Blood pressure abnormal ": 5.4355459418869145, "Blood pressure decreased ": 5.765291014534246, "Brain natriuretic peptide increased ": 18.55263830961768, "Cardiac failure ": 2.221142067979164, "Cardiothoracic ratio increased ": 259.63979882364947, "Catheter site erythema ": 58.58749674255598, "Catheter site infection ": 37.15445880914137, "Clostridium difficile infection ": 3.517549486517138, "Complication associated with device ": 16.339972209523477, "Concomitant disease aggravated ": 10.726858528952008, "Device breakage ": 16.9709243175089, "Device related infection ": 6.592508650715661, "Diarrhoea ": 2.3559216030963017, "Drug intolerance ": 2.084243444715785, "Dyspepsia ": 3.860989987772288, "Dyspnoea ": 2.459017132234253, "Dyspnoea exertional ": 12.824523977657682, "Ear discomfort ": 3.972356740289452, "Fluid retention ": 17.165358852597656, "Flushing ": 6.115299737631473, "Gastrooesophageal reflux disease ": 5.202931402120904, "Haemoglobin decreased ": 2.208148326650264, "Haemoptysis ": 3.2755053627031425, "Head injury ": 3.407176019874939, "Hospitalisation ": 4.697665291767141, "Hypervolaemia ": 17.56384877407431, "Hypotension ": 6.084273809446781, "Hypoxia ": 3.897665608226816, "Infusion site erythema ": 21.72114957276768, "Infusion site infection ": 120.68576651036204, "Infusion site pain ": 51.3638777441586, "Infusion site pruritus ": 52.15594348002582, "Infusion site reaction ": 31.05025116633616, "Infusion site swelling ": 34.219016949031506, "Iron deficiency anaemia ": 12.131862212352932, "Nasal congestion ": 6.332022762905129, "Nasopharyngitis ": 2.000140900098144, "Oedema ": 5.30380729086785, "Oedema peripheral ": 4.5402496842493125, "Oliguria ": 6.724281081010858, "Oxygen saturation decreased ": 9.67984937874514, "Pain in jaw ": 33.97084848612666, "Pericardial effusion ": 3.158395033791112, "Product dose omission issue ": 3.0888796361810225, "Productive cough ": 2.4414356644276016, "Pulmonary arterial hypertension ": 42.91335308582476, "Pulmonary hypertension ": 15.367376900273689, "Pulmonary oedema ": 2.947910859645714, "Purpura ": 2.712762989969136, "Radiation pneumonitis ": 54.69337486707991, "Respiratory failure ": 2.543380793187238, "Retching ": 2.6671319913359435, "Right ventricular failure ": 34.15061787427038, "Sickle cell anaemia with crisis ": 15.43620096209162, "Skin discolouration ": 2.2127222165957288, "Therapy non-responder ": 3.923727335789287, "Thyroid mass ": 14.75452783090638, "Transfusion ": 7.489274457862896, "Treatment noncompliance ": 2.185169553759043, "Unevaluable event ": 7.043618286334845, "Upper respiratory tract inflammation ": 42.805849628433954, "Uterine haemorrhage ": 9.06019176767264, "Vascular device infection ": 14.688126258422871, "Weight fluctuation ": 14.526967068293562, "Weight increased ": 2.596112598162445}
\ No newline at end of file
+{"Alanine aminotransferase increased": 12.476180096397185, "Blood creatine phosphokinase increased": 15.445436409911636, "Blood creatinine increased": 12.223504211243814, "Blood phosphorus decreased": 505.4596392655991, "Bone pain": 6.414905892664548, "Drug ineffective": 5.305709499484077, "Drug resistance": 162.91823534825764, "Fanconi syndrome acquired": 68.25145392066845, "Hepatic function abnormal": 3.9970933837906446, "Hepatitis B DNA increased": 541.6693372279842, "Osteoporosis": 4.717083502807063, "Pathogen resistance": 51.170480911540366, "Product complaint": 22.58273994844667, "Renal failure": 2.0294314169901075, "Renal impairment": 7.132376516903422, "Renal injury": 3.734831100977009, "Viral infection": 24.28293418155065, "Viral load increased": 155.48106806424838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/290.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/290.json
index 48cd7b69592..5643596229f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/290.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/290.json
@@ -1 +1 @@
-{"Angina pectoris ": 47.49339020417307, "Aphthous ulcer ": 143.07621289750065, "Arrhythmia ": 22.92917334070321, "Balanoposthitis ": 357.265502649812, "Diarrhoea ": 3.406447806136599, "Drug intolerance ": 22.426553224616264, "Eczema ": 56.141500484418025, "Hypertension ": 8.4274635963524, "Muscle spasms ": 15.520951788371654, "Oropharyngeal pain ": 20.3108929873496, "Pain ": 3.4695799844341626, "Palpitations ": 9.941292060448715, "Polyarthritis ": 332.39268654815885, "Pruritus ": 4.944102466946936, "Rash ": 3.737963742125257, "Tachycardia ": 10.315609476810822, "Vomiting ": 3.670870204583478}
\ No newline at end of file
+{"Abdominal pain lower": 2.2595444499864263, "Abnormal menstrual clots": 4.497464173875331, "Abnormal uterine bleeding": 2.8015424085311595, "Abnormal withdrawal bleeding": 6.905039712513494, "Acute aseptic arthritis": 3.3698833186622426, "Acute polyneuropathy": 2.2958612445942874, "Acute stress disorder": 3.8511348502502742, "Acute vestibular syndrome": 6.05886582624056, "Adenomyosis": 4.328542254621087, "Administration site erythema": 4.782743190788541, "Administration site joint pain": 4.499670795950392, "Administration site lymphadenopathy": 4.451759235938949, "Administration site movement impairment": 4.3172654387721074, "Administration site oedema": 9.050397802821914, "Administration site pain": 10.555401495208908, "Administration site paraesthesia": 3.6425063876375896, "Administration site reaction": 4.7793669675371575, "Adnexa uteri pain": 6.401559349889624, "Adrenocortical steroid therapy": 3.775145980829778, "Allergy to arthropod sting": 2.0888357176228958, "Alopecia areata": 2.2223593224735665, "Amenorrhoea": 12.263344567253128, "Anaesthesia": 5.811394043125332, "Anosmia": 2.387265662850641, "Anovulatory cycle": 9.029687703071833, "Anti-thyroid antibody increased": 4.237198194502826, "Antibody-dependent enhancement": 7.300215894772826, "Application site hypoaesthesia": 3.436574257038675, "Application site lymphadenopathy": 11.120928786800206, "Application site movement impairment": 5.683954618085744, "Application site swelling": 2.020440724674948, "Arrhythmia": 2.730040423205399, "Arthralgia": 2.424387195982871, "Arthritis reactive": 2.983283030680931, "Autoantibody positive": 4.524641230985584, "Autoantibody test": 4.192998844844487, "Autoimmune myositis": 2.65566004690295, "Axillary lymphadenectomy": 2.1362520709989847, "Axillary mass": 4.794032710695114, "Axillary pain": 7.463245206185721, "Axonal and demyelinating polyneuropathy": 2.515307204370868, "Basilar artery thrombosis": 2.76213548098781, "Bell's palsy": 2.770329639672858, "Body 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3.632306489687204, "Chills": 2.3506601075407443, "Chronic fatigue syndrome": 4.648547290140723, "Chronic idiopathic pain syndrome": 2.574763237365931, "Circumoral swelling": 2.7852425236339804, "Clinically isolated syndrome": 2.869292159030437, "Coital bleeding": 4.857512809936699, "Cold urticaria": 2.3656814270246915, "Concomitant drug effect decreased": 3.212988547658664, "Costochondritis": 2.19928968043676, "Cramp-fasciculation syndrome": 3.7094552762119446, "Creutzfeldt-Jakob disease": 2.2559285948500323, "Cystitis noninfective": 3.8184021863473143, "Dengue virus test positive": 6.567174982408364, "Dental paraesthesia": 2.0589716750462825, "Dermal filler reaction": 2.4937826409179054, "Diaphragmalgia": 2.2250160954174683, "Disturbance in attention": 2.043077492710574, "Dysaesthesia": 3.0107817784583637, "Dysmenorrhoea": 10.925482617758004, "Ear discomfort": 2.664469119700611, "Ear inflammation": 3.950705123943216, "Electrocardiogram PR segment depression": 6.24131628239582, 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2.730860511511366, "Puncture site erythema": 2.3513473106733978, "Puncture site oedema": 6.81818455681856, "Puncture site pain": 9.116959604817644, "Puncture site pruritus": 5.068857063625577, "Puncture site reaction": 3.918566212770695, "Puncture site swelling": 2.086344314666861, "Rest regimen": 2.2409720988589985, "Reversed hot-cold sensation": 2.626573297646525, "Rheumatic disorder": 2.8690511326291657, "SARS-CoV-2 antibody test": 2.9169185271388414, "SARS-CoV-2 antibody test negative": 10.118490602244329, "SARS-CoV-2 antibody test positive": 3.56437565078739, "SARS-CoV-2 test negative": 3.1721936968124043, "SARS-CoV-2 test positive": 4.4457074317200735, "Sacroiliac joint dysfunction": 2.522581185076515, "Scar discomfort": 6.75696843123994, "Scar inflammation": 2.301818247471489, "Sensory disturbance": 2.0188416693886952, "Sensory level abnormal": 5.5297479220707615, "Sensory overload": 2.709964778643328, "Shoulder injury related to vaccine administration": 4.16200958546239, "Sick 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neuropathy": 2.392660642429148, "Troponin": 2.2577398646546056, "Troponin abnormal": 5.372928219550427, "Troponin increased": 2.0531824432295034, "Unexpected vaginal bleeding on hormonal IUD": 6.250018862477208, "Urticaria chronic": 2.373579197427477, "Uterine inflammation": 2.969330260337686, "Uterine pain": 8.000411471654123, "Uterine spasm": 4.495090493339423, "Uterine tenderness": 2.89511937733927, "Vaccination failure": 10.486846626870584, "Vaccination site anaesthesia": 2.367091894156062, "Vaccination site atrophy": 2.126837169330628, "Vaccination site bruising": 3.310101819935221, "Vaccination site coldness": 2.7856817964749263, "Vaccination site discharge": 2.0130939076213488, "Vaccination site discolouration": 2.319709517087196, "Vaccination site discomfort": 2.3886811124851635, "Vaccination site dysaesthesia": 4.902165022523647, "Vaccination site erythema": 4.216199733982142, "Vaccination site haematoma": 4.797659734049902, "Vaccination site haemorrhage": 4.298182732894576, "Vaccination site hyperaesthesia": 5.497140044852421, "Vaccination site hypersensitivity": 2.5454564037404284, "Vaccination site hypoaesthesia": 6.993749150244167, "Vaccination site induration": 3.6141472883530215, "Vaccination site inflammation": 2.948383240996125, "Vaccination site injury": 2.893751629401894, "Vaccination site joint discomfort": 2.094124968275052, "Vaccination site joint erythema": 3.1962597357609708, "Vaccination site joint inflammation": 6.322604324826986, "Vaccination site joint movement impairment": 4.5635669983705, "Vaccination site joint pain": 5.359083487324133, "Vaccination site joint swelling": 4.612035948431808, "Vaccination site lymphadenopathy": 11.675879322485272, "Vaccination site mass": 2.666952652011448, "Vaccination site movement impairment": 5.1132345412983655, "Vaccination site necrosis": 3.756547186484228, "Vaccination site nerve damage": 4.572165599670352, "Vaccination site nodule": 2.085496031126291, "Vaccination site oedema": 5.74941481186386, "Vaccination site pain": 6.904037495364273, "Vaccination site paraesthesia": 7.619313059900217, "Vaccination site pruritus": 5.398426831029988, "Vaccination site reaction": 3.949188857063099, "Vaccination site scab": 2.2895739086620366, "Vaccination site scar": 2.3152195951034886, "Vaccination site swelling": 4.922309750134531, "Vaccination site thrombosis": 4.173967020046134, "Vaccination site ulcer": 3.4815812034308427, "Vaccination site urticaria": 2.182649899687352, "Vaccination site warmth": 2.795540129451226, "Vaccine breakthrough infection": 2.958806811381425, "Varicophlebitis": 2.2215181852691925, "Vascular pain": 2.1762261530502727, "Venous thrombosis limb": 3.100909232320553, "Vertebral artery dissection": 2.6331853142995003, "Vertebrobasilar stroke": 2.203695591089879, "Vertigo positional": 2.907597197424005, "Vestibular neuronitis": 5.591276922453304, "Weight bearing difficulty": 5.990621325849348}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/291.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/291.json
index 4baa087758a..7be3d8cdf3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/291.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/291.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 7.507020106136249, "Affect lability ": 3.74923040719733, "Aggression ": 3.213791618459928, "Agitation ": 6.700315298240646, "Akinesia ": 135.48880027440038, "Amimia ": 287.49336409222485, "Apathy ": 5.431748990424147, "Aspartate aminotransferase increased ": 2.654184920927416, "Aspiration ": 5.616510836806592, "Balance disorder ": 2.838920545377138, "Behaviour disorder ": 7.093137508086747, "Blood alkaline phosphatase increased ": 3.678638292998556, "Blood creatine phosphokinase increased ": 5.882001423050908, "Blood lactate dehydrogenase increased ": 2.8737626370562177, "Blood pressure fluctuation ": 4.235586943060363, "Bradykinesia ": 24.09326408405268, "C-reactive protein increased ": 3.2063918358434558, "Choking ": 6.046088126811237, "Chromaturia ": 15.02122212759018, "Cognitive disorder ": 2.809042268202215, "Colitis microscopic ": 15.714081148161643, "Coma ": 3.6829835114493887, "Compulsive shopping ": 86.35070521208279, "Confusional state ": 4.003169135381908, "Constipation ": 3.308252349782721, "Corneal reflex decreased ": 163.64007628756076, "Decreased activity ": 5.06970309985907, "Dehydration ": 3.2923144163357216, "Delirium ": 4.029557949027159, "Delusion ": 18.32715472714668, "Dementia ": 3.33866622885214, "Depressed level of consciousness ": 2.199421167886222, "Disorientation ": 5.110955595625864, "Dyskinesia ": 37.02323090008107, "Dysphagia ": 15.53734763872584, "Dysstasia ": 2.46547744618903, "Dystonia ": 6.988147821292804, "Eating disorder ": 4.329843932287485, "Fall ": 4.432481600411295, "Feeling abnormal ": 2.1098250111916577, "Foreign body in throat ": 14.564890833762073, "Freezing phenomenon ": 67.19127695877536, "Gait disturbance ": 4.0188187696866455, "Gait inability ": 3.5663399119569354, "Gamma-glutamyltransferase increased ": 2.878456788201641, "Haematocrit decreased ": 3.7899886212270286, "Hallucination ": 20.257883233955383, "Hallucination, visual ": 27.14727310831451, "Hyperreflexia ": 12.61071844826304, "Hyperthermia ": 4.482289071198148, "Hypertonia ": 11.321824416896892, "Hypokinesia ": 4.05035611719886, "Hypomania ": 13.836712275631216, "Ileus ": 5.105548748995882, "Immobile ": 14.23706885878834, "Irritability ": 2.936880922987732, "Leukocytosis ": 3.353441305859976, "Movement disorder ": 4.792740523184088, "Muscle rigidity ": 33.26051489828492, "Musculoskeletal stiffness ": 3.2392747716831938, "Neuroleptic malignant syndrome ": 17.09824342074636, "Neurosis ": 66.36416249117842, "On and off phenomenon ": 114.64384055491416, "Paranoia ": 7.937459235975657, "Parkinson's disease ": 141.7651698625537, "Parkinsonism ": 7.084402574685902, "Persistent depressive disorder ": 78.08807940996124, "Pneumonia aspiration ": 9.740242249959108, "Posture abnormal ": 27.45842688537308, "Product availability issue ": 17.015426290426387, "Product complaint ": 6.956087761267162, "Product use complaint ": 12.876704535639782, "Psychiatric symptom ": 15.043310369274588, "Psychomotor hyperactivity ": 13.854426122129828, "Psychotic behaviour ": 51.64729196331477, "Psychotic disorder ": 4.474774417384658, "Red blood cell count decreased ": 2.3194771085177304, "Red blood cell sedimentation rate increased ": 11.715200002693567, "Restlessness ": 2.4299178327843176, "Rhabdomyolysis ": 5.59982229076503, "Rheumatic disorder ": 14.523453796676922, "Road traffic accident ": 4.141294074063699, "Serotonin syndrome ": 3.4868355968211087, "Somnolence ": 2.316880614122529, "Speech disorder ": 2.06224996574895, "Sputum discoloured ": 6.939904049131369, "Sudden onset of sleep ": 117.08395008402184, "Therapeutic product effect delayed ": 17.956448450638707, "Therapeutic response shortened ": 81.8669098850534, "Thymus disorder ": 256.7979562969939, "Tremor ": 2.934138892122291, "Urinary incontinence ": 2.0885651192381705, "Wrong technique in product usage process ": 13.49851266687642}
\ No newline at end of file
+{"Acute kidney injury": 8.674211108635001, "Hypoglycaemia": 52.72764181620155, "Lactic acidosis": 78.00036413067367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/292.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/292.json
index 66599bed4f0..2483af44c78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/292.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/292.json
@@ -1 +1 @@
-{"Blood creatine phosphokinase increased ": 9.679262533508048, "Condition aggravated ": 3.436668261909721, "Confusional state ": 3.301902537618365, "Dehydration ": 4.819277904395349, "Diarrhoea ": 3.065962396846828, "Drug interaction ": 3.3320361221319508, "Dyskinesia ": 29.66992297410299, "Fall ": 4.386946394833204, "Gait disturbance ": 2.5835720337228936, "Hallucination ": 7.980632661421253, "Hypokinesia ": 43.0847079988824, "Liver function test abnormal ": 12.673551314986488, "Rhabdomyolysis ": 10.68367494008711, "Weight decreased ": 2.764306157869938}
\ No newline at end of file
+{"Eosinophilia": 41.24530569511127, "Gamma-glutamyltransferase increased": 16.21460878059043, "Hepatic cytolysis": 48.42793068909916, "Hepatic function abnormal": 9.63094524108071, "Insomnia": 3.4531784156906857, "Oedema": 12.91950466584628, "Skin exfoliation": 22.56718752593687, "Suspected counterfeit product": 408.5722481012281, "Weight decreased": 3.5865896688447374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/293.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/293.json
index 38a81a325ed..f15584df943 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/293.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/293.json
@@ -1 +1 @@
-{"Abdominal pain ": 24.79329051739857, "Constipation ": 46.78458032581067, "Nausea ": 5.324444641354957, "Vomiting ": 8.733344386982521}
\ No newline at end of file
+{"Chills": 11.469119971039932}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/294.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/294.json
index 04c856e1d40..990350448fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/294.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/294.json
@@ -1 +1 @@
-{"Anhedonia ": 3.1655396872128843, "Anxiety ": 2.439137521797732, "Balance disorder ": 4.5160249647354895, "Bone pain ": 2.739135943318313, "Burning sensation ": 4.498329746871734, "Deformity ": 78.4155383283577, "Dry skin ": 21.77286039616827, "Emotional distress ": 4.303460161890472, "Erythema ": 3.385126887416767, "Extremity contracture ": 410.1498784139749, "Fibrosis ": 70.83132362950919, "Gait inability ": 3.691080789939184, "General physical health deterioration ": 5.581448467924595, "Hyperkeratosis ": 29.147141242189623, "Injury ": 10.158087729769807, "Joint range of motion decreased ": 78.02612673435942, "Joint stiffness ": 27.12880409702899, "Mobility decreased ": 14.405859385082197, "Muscular weakness ": 5.719382308944905, "Musculoskeletal stiffness ": 6.8184519483309085, "Nephrogenic systemic fibrosis ": 262.02365246068035, "Neuropathy peripheral ": 2.0037472985862603, "Oedema ": 5.161057756807073, "Oedema peripheral ": 9.477298474729473, "Pain in extremity ": 2.026723948657412, "Rash papular ": 10.835913100096136, "Scar ": 85.08085862769995, "Skin burning sensation ": 10.057376272929451, "Skin discolouration ": 15.453762978229731, "Skin disorder ": 6.911590898476638, "Skin exfoliation ": 6.165447605199485, "Skin fibrosis ": 175.33973903413334, "Skin fissures ": 40.31965496019155, "Skin hyperpigmentation ": 82.6334529674112, "Skin hypertrophy ": 237.54789074649744, "Skin induration ": 325.4943185846071, "Skin lesion ": 6.945824595197582, "Skin plaque ": 75.81421967151907, "Skin tightness ": 277.2311767228233, "Swelling ": 2.127304036095246}
\ No newline at end of file
+{"Angina pectoris": 47.49339020417307, "Aphthous ulcer": 143.07621289750065, "Arrhythmia": 22.92917334070321, "Balanoposthitis": 357.265502649812, "Diarrhoea": 3.4064193801272493, "Drug intolerance": 22.426553224616264, "Eczema": 56.141500484418025, "Hypertension": 8.427376605150252, "Muscle spasms": 15.520951788371654, "Oropharyngeal pain": 20.3108929873496, "Pain": 3.4695504950191927, "Palpitations": 9.941292060448715, "Polyarthritis": 332.39268654815885, "Pruritus": 4.944042586407156, "Rash": 3.737912400276461, "Tachycardia": 10.3153488045305, "Vomiting": 3.670820689273826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/295.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/295.json
index 119f8ebd336..cd008f1b41e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/295.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/295.json
@@ -1 +1 @@
-{"Blood pressure increased ": 7.09155877008656, "Oedema peripheral ": 11.175338583637824, "Wrong technique in product usage process ": 24.675147702071957}
\ No newline at end of file
+{"Abnormal behaviour": 7.507020106136249, "Affect lability": 3.74923040719733, "Aggression": 3.213791618459928, "Agitation": 6.700315298240646, "Akinesia": 135.48880027440038, "Amimia": 287.49336409222485, "Apathy": 5.431748990424147, "Aspartate aminotransferase increased": 2.654184920927416, "Aspiration": 5.616510836806592, "Balance disorder": 2.838920545377138, "Behaviour disorder": 7.093137508086747, "Blood alkaline phosphatase increased": 3.678638292998556, "Blood creatine phosphokinase increased": 5.882001423050908, "Blood lactate dehydrogenase increased": 2.8737626370562177, "Blood pressure fluctuation": 4.235586943060363, "Bradykinesia": 24.09326408405268, "C-reactive protein increased": 3.2063918358434558, "Choking": 6.046088126811237, "Chromaturia": 15.02122212759018, "Cognitive disorder": 2.809042268202215, "Colitis microscopic": 15.714081148161643, "Coma": 3.6829835114493887, "Compulsive shopping": 86.35070521208279, "Confusional state": 4.003169135381908, "Constipation": 3.308252349782721, "Corneal reflex decreased": 163.64007628756076, "Decreased activity": 5.06970309985907, "Dehydration": 3.2921385308285025, "Delirium": 4.029557949027159, "Delusion": 18.32715472714668, "Dementia": 3.33866622885214, "Depressed level of consciousness": 2.199421167886222, "Disorientation": 5.110955595625864, "Dyskinesia": 37.02323090008107, "Dysphagia": 15.53734763872584, "Dysstasia": 2.4649163067246787, "Dystonia": 6.988147821292804, "Eating disorder": 4.329843932287485, "Fall": 4.432367827742025, "Feeling abnormal": 2.1097843811140664, "Foreign body in throat": 14.564890833762073, "Freezing phenomenon": 67.19127695877536, "Gait disturbance": 4.018745830393974, "Gait inability": 3.5663399119569354, "Gamma-glutamyltransferase increased": 2.878456788201641, "Haematocrit decreased": 3.7899886212270286, "Hallucination": 20.257883233955383, "Hallucination, visual": 27.14727310831451, "Hyperreflexia": 12.61071844826304, "Hyperthermia": 4.482289071198148, "Hypertonia": 11.321824416896892, "Hypokinesia": 4.05035611719886, "Hypomania": 13.836712275631216, "Ileus": 5.105548748995882, "Immobile": 14.23706885878834, "Irritability": 2.9367405916663856, "Leukocytosis": 3.353441305859976, "Movement disorder": 4.792740523184088, "Muscle rigidity": 33.26051489828492, "Musculoskeletal stiffness": 3.2392747716831938, "Neuroleptic malignant syndrome": 17.09824342074636, "Neurosis": 66.36416249117842, "On and off phenomenon": 114.64384055491416, "Paranoia": 7.937459235975657, "Parkinson's disease": 141.7651698625537, "Parkinsonism": 7.084402574685902, "Persistent depressive disorder": 78.08807940996124, "Pneumonia aspiration": 9.740242249959108, "Posture abnormal": 27.45842688537308, "Product availability issue": 17.015426290426387, "Product complaint": 6.956087761267162, "Product use complaint": 12.876704535639782, "Psychiatric symptom": 15.043310369274588, "Psychomotor hyperactivity": 13.85202409203312, "Psychotic behaviour": 51.64729196331477, "Psychotic disorder": 4.474774417384658, "Red blood cell count decreased": 2.3194771085177304, "Red blood cell sedimentation rate increased": 11.715200002693567, "Restlessness": 2.429789615765583, "Rhabdomyolysis": 5.59982229076503, "Rheumatic disorder": 14.523453796676922, "Road traffic accident": 4.141294074063699, "Serotonin syndrome": 3.4868355968211087, "Somnolence": 2.3168550586716483, "Speech disorder": 2.06224996574895, "Sputum discoloured": 6.939904049131369, "Sudden onset of sleep": 117.08395008402184, "Therapeutic product effect delayed": 17.956448450638707, "Therapeutic response shortened": 81.8669098850534, "Thymus disorder": 256.7979562969939, "Tremor": 2.93402796946593, "Urinary incontinence": 2.0885651192381705, "Wrong technique in product usage process": 13.49851266687642}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/296.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/296.json
index 12e144726c7..801dfd78e4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/296.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/296.json
@@ -1 +1 @@
-{"Diabetes mellitus inadequate control ": 10.742450278118293, "Drug interaction ": 2.016172609503253, "Drug resistance ": 18.85088162336985, "Exposure during pregnancy ": 5.354484636240363, "Hyperglycaemia ": 5.656524775072676, "Hypoglycaemia ": 4.263958426578721, "Neutropenia ": 4.329783256470271, "Sepsis ": 3.526667121433084, "Tendon rupture ": 43.66720773922663}
\ No newline at end of file
+{"Blood creatine phosphokinase increased": 9.679262533508048, "Condition aggravated": 3.436668261909721, "Confusional state": 3.301902537618365, "Dehydration": 4.819020687038352, "Diarrhoea": 3.0659368094362573, "Drug interaction": 3.3320361221319508, "Dyskinesia": 29.66992297410299, "Fall": 4.386833938481384, "Gait disturbance": 2.583525202831101, "Hallucination": 7.980632661421253, "Hypokinesia": 43.0847079988824, "Liver function test abnormal": 12.673551314986488, "Rhabdomyolysis": 10.68367494008711, "Weight decreased": 2.764306157869938}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/297.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/297.json
index 7926ff1f129..67e6b88a2e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/297.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/297.json
@@ -1 +1 @@
-{"Ammonia increased ": 66.1559910842339, "Atrioventricular block ": 26.20967723560282, "Blood glucose increased ": 3.979184796112179, "Drug ineffective ": 2.8646507179211107, "Electrocardiogram QT prolonged ": 6.182824181576268, "Extrapyramidal disorder ": 17.00860541866718, "Heart rate decreased ": 10.77143943380814, "Hyperglycaemia ": 5.122187241592768, "Maternal exposure during pregnancy ": 4.2380256575224085, "Premature delivery ": 22.918067778130204, "Presyncope ": 4.854771962447388, "Sepsis ": 2.982044049604561, "Tendon rupture ": 38.47378654180518, "Therapeutic product effect decreased ": 6.573842814511015}
\ No newline at end of file
+{"Abdominal pain": 24.79329051739857, "Constipation": 46.78458032581067, "Nausea": 5.324420343917252, "Vomiting": 8.733226584141024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/298.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/298.json
index 1be13b336be..bba9f60af12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/298.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/298.json
@@ -1 +1 @@
-{"Abscess ": 2.52569870338455, "Abscess limb ": 4.36418901000244, "Accidental exposure to product ": 7.912577665945781, "Accidental underdose ": 2.328176361134584, "Acne ": 2.2428569208046785, "Acrochordon ": 12.097881620985778, "Actinic keratosis ": 5.072209229141919, "Acute febrile neutrophilic dermatosis ": 3.291637019025799, "Adenocarcinoma of colon ": 2.96946792068669, "Adjustment disorder with depressed mood ": 2.107435768358259, "Amyotrophic lateral sclerosis ": 2.492841703011177, "Anal abscess ": 2.2380244819653226, "Ankylosing spondylitis ": 42.79634456688247, "Antinuclear antibody increased ": 6.426610524567921, "Aphthous ulcer ": 4.293180894961076, "Arthritis ": 5.940349574184624, "Arthritis bacterial ": 3.392257456594186, "Arthrodesis ": 19.113289327343, "Arthropathy ": 3.7602168578615736, "Arthropod bite ": 2.0050481045629764, "Back pain ": 2.347618568762316, "Bacterial vaginosis ": 14.33221595623343, "Basal cell carcinoma ": 2.1524853534585784, "Behcet's syndrome ": 5.472421978327979, "Blepharitis ": 2.2490054255730696, "Blood albumin decreased ": 2.1558152199800573, "Blood pressure diastolic decreased ": 2.3694633946873718, "Blood pressure systolic increased ": 3.1590746901677287, "Body temperature decreased ": 3.966487771424029, "Bone erosion ": 4.228706810280589, "Bone lesion ": 4.529138298025233, "Bone marrow oedema ": 13.25935635463006, "Bowel movement irregularity ": 4.893033449740591, "Bronchitis ": 2.571864779374616, "Bursitis ": 3.795303492856888, "C-reactive protein ": 4.4201398535117855, "C-reactive protein abnormal ": 3.9448274322019774, "C-reactive protein increased ": 4.870262000043046, "Candida infection ": 6.045459919024995, "Cellulitis ": 3.4703959725346887, "Chest injury ": 6.3104677877748845, "Chronic disease ": 23.99814600976756, "Colitis ": 3.492756924230825, "Colitis microscopic ": 4.077599122346428, "Colitis ulcerative ": 6.019661948714094, "Concomitant disease aggravated ": 8.250146883396864, "Concomitant disease progression ": 2.954334194473744, "Conjunctivitis ": 3.196776240243239, "Contraindicated product prescribed ": 9.612736943103892, "Coronavirus infection ": 6.081690773725959, "Coronavirus test positive ": 8.119223556548526, "Costochondritis ": 3.610212928150271, "Crepitations ": 2.0553382281969568, "Crohn's disease ": 10.749434728169051, "Cutaneous T-cell lymphoma ": 7.431602326619571, "Cutaneous symptom ": 6.216520658971286, "Cutaneous vasculitis ": 2.503334291939256, "Cyst ": 2.2259686668919585, "Cystitis noninfective ": 2.509603929525813, "Dactylitis ": 91.03610429089922, "Decreased immune responsiveness ": 5.529363435880501, "Deep vein thrombosis postoperative ": 2.4346307453061944, "Defaecation urgency ": 3.992513109940826, "Dermatitis atopic ": 2.191661171766386, "Dermatitis exfoliative generalised ": 4.553229767904019, "Dermatitis psoriasiform ": 10.67243489242479, "Device defective ": 15.197844020900003, "Device delivery system issue ": 2.1347816771147965, "Device difficult to use ": 4.434522644785563, "Device issue ": 9.570934941244367, "Device leakage ": 5.112306632269688, "Device malfunction ": 3.266931655760719, "Diarrhoea haemorrhagic ": 4.566369699487118, "Discomfort ": 2.145706096494832, "Dislocation of vertebra ": 3.811897343632617, "Diverticulitis ": 2.804862020322839, "Drug dose omission by device ": 6.135189950199675, "Drug effect less than expected ": 3.0372034535735777, "Drug hypersensitivity ": 2.3337439615204767, "Drug ineffective ": 3.475136686903724, "Drug intolerance ": 3.58841703098957, "Dry eye ": 2.0700465359581317, "Dry skin ": 3.1681051714708093, "Duodenal ulcer perforation ": 2.0646421585826, "Dyshidrotic eczema ": 8.783593857812683, "Ear disorder ": 4.05748409752101, "Ear infection ": 2.9954445257016973, "Ear injury ": 27.19132323118374, "Ear neoplasm ": 66.08935205959591, "Ear pruritus ": 3.0734887906043507, "Early satiety ": 9.073528726766863, "Eczema ": 3.6496983025429497, "Endometriosis ": 2.5539051015581298, "Enteritis ": 3.3092100893222827, "Enthesopathy ": 39.089396612690194, "Epicondylitis ": 4.008275732381999, "Erosive oesophagitis ": 2.948777973245726, "Erysipelas ": 5.607921656211831, "Erythema nodosum ": 3.3776974736758074, "Erythrodermic psoriasis ": 36.56684205670264, "Exposure via partner ": 33.01741294795728, "Eye discharge ": 2.450177049765646, "Eye infection ": 3.0420848318206075, "Facet joint syndrome ": 3.220238694208837, "Faecal calprotectin increased ": 6.0129409029097545, "Fear of injection ": 6.984317907002021, "Fibromyalgia ": 2.4855993938368783, "Finger deformity ": 2.8642970779499137, "Fistula ": 2.4095890673210354, "Folliculitis ": 3.7987659768374793, "Food aversion ": 4.437244035441716, "Fungal infection ": 5.684832874673858, "Furuncle ": 6.551826109813355, "Gastrectomy ": 22.427734851461462, "Gastrointestinal candidiasis ": 11.43218775067814, "Gastrointestinal disorder ": 2.402319398403429, "Gastrointestinal infection ": 3.09794455258931, "Gastrointestinal inflammation ": 4.1816844459102445, "Genital candidiasis ": 10.840906674017862, "Grip strength decreased ": 3.018134458158565, "Guttate psoriasis ": 11.3743299482559, "Haemangioma of skin ": 12.872230297427013, "Haematochezia ": 2.2197076841544248, "Haemorrhagic diathesis ": 2.782832673692019, "Hangover ": 2.1898544143979284, "Hepatic enzyme abnormal ": 3.670627463410838, "Hepatic steatosis ": 3.1343212748256826, "Hereditary motor and sensory neuropathy ": 32.82005858996298, "Hidradenitis ": 23.246949127168527, "Hordeolum ": 2.834271164812374, "Hypertriglyceridaemia ": 2.4572363129928765, "Immune system disorder ": 2.097659493482929, "Immunodeficiency ": 2.918430167373996, "Immunosuppression ": 4.439740198690783, "Impetigo ": 4.772251005820685, "Inappropriate schedule of product administration ": 6.250176592315128, "Incorrect dose administered ": 4.586620865936073, "Incorrect dose administered by device ": 5.801520629896028, "Incorrect route of product administration ": 3.514905890379844, "Infection ": 2.8675140210450927, "Infection susceptibility increased ": 4.296125625596934, "Inflammation ": 3.589610271419706, "Inflammatory bowel disease ": 64.29945591752977, "Inflammatory marker increased ": 2.503911933639708, "Inflammatory pain ": 16.044364273902605, "Injection site bruising ": 5.116924717067456, "Injection site discharge ": 9.428336623359266, "Injection site haemorrhage ": 4.676857768114068, "Injection site mass ": 3.207441747723927, "Intervertebral disc degeneration ": 2.287497937807741, "Investigation abnormal ": 8.276375766553237, "Iodine allergy ": 27.8583954251844, "Iridocyclitis ": 3.038457437875414, "Iritis ": 10.13588049167989, "Joint ankylosis ": 59.35353231004366, "Joint noise ": 3.201232425602569, "Joint range of motion decreased ": 6.383593828039476, "Joint stiffness ": 4.589818025062403, "Joint swelling ": 4.798686794716206, "Juvenile idiopathic arthritis ": 5.946446007780346, "KL-6 increased ": 6.994506588095212, "Kidney infection ": 2.669989993338089, "Large intestinal ulcer ": 2.842273172174308, "Laryngitis ": 3.970729552398789, "Latent tuberculosis ": 5.61445558545964, "Lentigo ": 44.756918601738896, "Lichen planus ": 4.228770675892275, "Lid sulcus deepened ": 15.520567113427768, "Lip dry ": 4.289316321982557, "Lip ulceration ": 6.169311991799358, "Lipoma ": 4.016182886060782, "Liver abscess ": 2.044992251511394, "Liver function test increased ": 3.012499009497676, "Loss of therapeutic response ": 18.901397180474618, "Lower gastrointestinal haemorrhage ": 5.791728642525092, "Lower limb fracture ": 2.052638464248524, "Lower respiratory tract congestion ": 14.648129714292685, "Lower respiratory tract infection ": 3.629777892119733, "Lower respiratory tract infection viral ": 21.99319991174285, "Lumbar spinal stenosis ": 3.207181305701119, "Lumbar vertebral fracture ": 4.873164840223964, "Lupus vulgaris ": 12.144596227927536, "Lupus-like syndrome ": 7.123378979068758, "Lyme disease ": 2.410843394885977, "Macule ": 6.390419258282256, "Malignant melanoma ": 2.524605838198359, "Mammoplasty ": 24.59267791278567, "Maternal exposure timing unspecified ": 5.557354257826239, "Melanocytic naevus ": 6.958519350054344, "Meniscus injury ": 4.474738329991791, "Mouth ulceration ": 3.685254843293102, "Mucous stools ": 2.5304662289178874, "Muscle atrophy ": 2.0121848816990338, "Muscle injury ": 4.395911360423021, "Muscle strain ": 3.952619581341313, "Musculoskeletal discomfort ": 3.5365620806802784, "Musculoskeletal pain ": 3.9722130393392767, "Musculoskeletal stiffness ": 5.495285825912794, "Mycobacterium tuberculosis complex test positive ": 9.647511425556411, "Mycotic allergy ": 6.427548504386733, "Nail disorder ": 3.4036219832946166, "Nail psoriasis ": 44.25870098606173, "Nasal crusting ": 24.603209856284334, "Nasal dryness ": 3.827693385275481, "Nasal inflammation ": 7.913814465870637, "Nasopharyngitis ": 4.428489005334835, "Neck pain ": 2.583259689843464, "Needle issue ": 6.358657303781159, "Neoplasm skin ": 5.27623807433815, "Nervous system disorder ": 2.24123722361904, "Neurodermatitis ": 3.995171721601437, "Nodule ": 2.669989993338089, "Normal newborn ": 3.969452053546088, "Obesity ": 3.3587241289799405, "Occult blood ": 8.706968915985879, "Oesophageal candidiasis ": 20.51816627698332, "Oesophageal stenosis ": 3.171997578848048, "Oesophageal ulcer ": 2.40515574524744, "Onycholysis ": 14.648129714292685, "Onychomycosis ": 2.2629235716491465, "Oral candidiasis ": 8.810117655092354, "Oral disorder ": 2.12682000959752, "Oral fungal infection ": 7.325967297772159, "Oral herpes ": 3.5874707218909667, "Oropharyngeal candidiasis ": 9.963380005889906, "Oropharyngeal pain ": 2.3821924009514395, "Osteoarthritis ": 4.137215310531088, "Otitis externa ": 10.757771677203424, "Otitis media ": 2.273908166734489, "Overweight ": 2.2880288254742767, "Pain of skin ": 2.575693410398263, "Palmoplantar pustulosis ": 37.98178771646722, "Papillary thyroid cancer ": 3.118088943510042, "Papule ": 4.101512271149069, "Paradoxical drug reaction ": 4.452448100510977, "Paradoxical psoriasis ": 28.843392104841904, "Paternal exposure during pregnancy ": 21.274910866504865, "Pelvic pain ": 2.842511887247708, "Peptic ulcer ": 4.725003900887934, "Peripheral venous disease ": 5.795138036411785, "Peritonsillar abscess ": 6.5848138188840855, "Pharyngitis ": 3.3515868093988828, "Pharyngitis streptococcal ": 6.251497993451569, "Phlebectomy ": 227.33299859301476, "Pigmentation disorder ": 2.1484689460044644, "Plantar fasciitis ": 3.963878381610708, "Pneumomediastinum ": 5.403606201727981, "Polyarthritis ": 2.8142327480251423, "Polycythaemia ": 7.965017940283153, "Post procedural infection ": 3.4569787862136243, "Product prescribing error ": 5.04855056575651, "Product supply issue ": 3.1035205710981297, "Productive cough ": 2.0279462924027083, "Psoriasis ": 39.92569355554707, "Psoriasis area severity index increased ": 80.19648950652187, "Psoriatic arthropathy ": 48.11329056998748, "Pustular psoriasis ": 23.172161021986867, "Pustule ": 6.540052962106897, "Pyoderma gangrenosum ": 5.891223976755102, "Rebound psoriasis ": 161.27938876942102, "Red blood cell sedimentation rate abnormal ": 5.642331779471181, "Red blood cell sedimentation rate increased ": 3.836412460617568, "Reflux gastritis ": 7.212499626338817, "Respiratory tract congestion ": 3.045733925402601, "Respiratory tract infection ": 3.143105094469613, "Rheumatic disorder ": 3.4180364181895464, "Rheumatic fever ": 6.047443122014809, "Rheumatoid arthritis ": 2.4841217416482557, "Rheumatoid factor positive ": 2.9875583937413666, "Rheumatoid nodule ": 5.595523023708395, "Rhinalgia ": 2.0550116016899658, "Rhinitis ": 2.0949740769619307, "Rhinorrhoea ": 2.543777205374451, "Sacral pain ": 5.821039060833801, "Sacroiliitis ": 19.029228100966705, "Scab ": 3.095811686173851, "Scar ": 2.3874912427344634, "Sciatica ": 4.055659332945938, "Scratch ": 5.547707903406603, "Seborrhoeic keratosis ": 21.611715625301198, "Secretion discharge ": 3.0352745286884857, "Self-consciousness ": 65.1095301150832, "Seronegative arthritis ": 19.946554934259595, "Sinonasal obstruction ": 11.382685651781973, "Sinus congestion ": 5.102520606158166, "Sinusitis ": 2.546945650341358, "Sjogren's syndrome ": 4.619092315069047, "Skin atrophy ": 2.4692166962664155, "Skin candida ": 20.578440603673084, "Skin depigmentation ": 3.16153305920081, "Skin disorder ": 3.736584258574296, "Skin exfoliation ": 4.968453040818748, "Skin fissures ": 5.682529090247976, "Skin haemorrhage ": 3.8344653786538543, "Skin hyperpigmentation ": 2.1340577362344697, "Skin hypertrophy ": 2.362568881825132, "Skin infection ": 2.7954161507559085, "Skin injury ": 3.938117823531039, "Skin lesion ": 8.08071623801856, "Skin mass ": 2.271506956394293, "Skin oedema ": 4.727968228820789, "Skin plaque ": 21.43006714705332, "Skin reaction ": 3.124216619833983, "Skin striae ": 3.662838799088658, "Skin wrinkling ": 4.698107230938798, "Sleep disorder due to general medical condition, hypersomnia type ": 143.69406594625357, "Somatic symptom disorder ": 2.216457840070845, "Spinal cord injury ": 10.174043451640424, "Spinal disorder ": 2.3270778295164583, "Spinal fusion surgery ": 2.397518654080057, "Spinal osteoarthritis ": 3.490399788800685, "Spinal pain ": 5.867844456714221, "Spinal stenosis ": 2.700813243213789, "Spondylitis ": 13.98240758343183, "Spondyloarthropathy ": 8.460794831368258, "Sputum discoloured ": 2.168630957434489, "Squamous cell carcinoma ": 2.151391849814364, "Staphylococcal infection ": 3.353025914641464, "Staphylococcal skin infection ": 8.742535551625716, "Staphylococcus test positive ": 2.7300292250070206, "Streptococcal infection ": 2.282523152190114, "Stress ": 2.9579064394750483, "Subcutaneous abscess ": 4.777035945422512, "Sunburn ": 3.093040029734667, "Swollen joint count ": 193.90144038620733, "Swollen joint count increased ": 6.280970407557677, "Symptom recurrence ": 9.20038656979777, "Synovial cyst ": 4.07387817867366, "Synovial disorder ": 20.44162869518447, "Synovitis ": 6.595041069634799, "Syringe issue ": 2.7156098018006425, "Telangiectasia ": 6.60480688470877, "Temporomandibular pain and dysfunction syndrome ": 5.05561558739295, "Tender joint count ": 190.28093922693932, "Tenderness ": 3.2346361041891734, "Tendon disorder ": 3.1349674617273133, "Tendonitis ": 2.472584472184263, "Tenosynovitis ": 14.289532217459625, "Terminal insomnia ": 7.886366758001173, "Therapeutic product effect decreased ": 4.677005106448232, "Therapeutic product effect delayed ": 2.425279654508431, "Therapeutic product effect incomplete ": 5.332645697918995, "Therapeutic response decreased ": 2.22522123528002, "Therapeutic response shortened ": 21.37171415345446, "Therapy non-responder ": 3.606394028063796, "Tinea pedis ": 21.988833235846776, "Tonsillar ulcer ": 77.85689721946959, "Tonsillitis ": 9.48165577894944, "Tooth abscess ": 9.125719320318892, "Treatment failure ": 6.406599800566071, "Trismus ": 3.1392118605221366, "Tuberculin test positive ": 4.117996980403709, "Tuberculosis ": 4.601726040171987, "Type 2 diabetes mellitus ": 2.3279311612414126, "Upper respiratory tract infection ": 2.8060854575602976, "Urticarial vasculitis ": 4.273948313706167, "Uveitis ": 10.97550471415921, "Vaginal infection ": 17.162057805852516, "Vitiligo ": 4.257702294001496, "Vulvovaginal candidiasis ": 9.740006650404643, "Vulvovaginal mycotic infection ": 4.146334966831085, "Wound infection ": 2.3432564418864805, "Wound secretion ": 5.913793630213956, "Wrong technique in device usage process ": 2.870427212535945}
\ No newline at end of file
+{"Anhedonia": 3.1655396872128843, "Anxiety": 2.439137521797732, "Balance disorder": 4.5160249647354895, "Bone pain": 2.739135943318313, "Burning sensation": 4.498329746871734, "Deformity": 78.4155383283577, "Dry skin": 21.77286039616827, "Emotional distress": 4.303460161890472, "Erythema": 3.3850937714823126, "Extremity contracture": 410.1498784139749, "Fibrosis": 70.83132362950919, "Gait inability": 3.691080789939184, "General physical health deterioration": 5.581448467924595, "Hyperkeratosis": 29.147141242189623, "Injury": 10.156612592839563, "Joint range of motion decreased": 78.02612673435942, "Joint stiffness": 27.12880409702899, "Mobility decreased": 14.405859385082197, "Muscular weakness": 5.719382308944905, "Musculoskeletal stiffness": 6.8184519483309085, "Nephrogenic systemic fibrosis": 262.02365246068035, "Neuropathy peripheral": 2.003686474386216, "Oedema": 5.161057756807073, "Oedema peripheral": 9.477064095734004, "Pain in extremity": 2.026713229831947, "Rash papular": 10.834715206520926, "Scar": 85.08085862769995, "Skin burning sensation": 10.057376272929451, "Skin discolouration": 15.453762978229731, "Skin disorder": 6.911590898476638, "Skin exfoliation": 6.165447605199485, "Skin fibrosis": 175.33973903413334, "Skin fissures": 40.31965496019155, "Skin hyperpigmentation": 82.6334529674112, "Skin hypertrophy": 237.54789074649744, "Skin induration": 325.4943185846071, "Skin lesion": 6.945824595197582, "Skin plaque": 75.81421967151907, "Skin tightness": 277.06006709871093, "Swelling": 2.127304036095246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/299.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/299.json
index 3ae237e03b7..0c03581e1ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/299.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/299.json
@@ -1 +1 @@
-{"Acne ": 3.555496705658454, "Acute kidney injury ": 2.278549547279668, "Aphthous ulcer ": 5.273353831346296, "Aspartate aminotransferase increased ": 2.138368435203255, "Blood alkaline phosphatase increased ": 4.519842431229907, "Blood bilirubin increased ": 2.102718310832065, "Blood creatine phosphokinase increased ": 6.72026706243508, "Blood creatinine increased ": 2.293544211276965, "Blood lactate dehydrogenase increased ": 4.249604998943078, "Cardiomyopathy ": 4.832497607997906, "Central serous chorioretinopathy ": 78.12012832584566, "Cholestasis ": 11.8751675120925, "Conjunctivitis ": 4.028240801491386, "Cytokine release syndrome ": 2.0423892588583823, "Death ": 3.509511679071972, "Dermatitis ": 4.807930120966674, "Dermatitis acneiform ": 62.81203508210757, "Dermatitis allergic ": 3.560205889772776, "Diarrhoea ": 4.079931491761429, "Disease progression ": 2.3066045223220164, "Drug reaction with eosinophilia and systemic symptoms ": 34.60012310026578, "Ejection fraction decreased ": 14.841143333941892, "Electrocardiogram QT prolonged ": 2.1219654170119924, "Eosinophilia ": 2.8094752618794923, "Erythema multiforme ": 3.710378415420109, "Erythema nodosum ": 19.465977813204223, "Face oedema ": 6.139019589925036, "Folliculitis ": 6.105949189442965, "Gamma-glutamyltransferase increased ": 2.860585250027473, "Gastritis ": 2.358326745641816, "General physical health deterioration ": 2.709891744217398, "Hepatic cytolysis ": 9.540794144793823, "Hepatitis ": 3.553001960603466, "Hepatotoxicity ": 3.9147110418945696, "Hyperthermia ": 4.8817078958393765, "Hypertransaminasaemia ": 5.8447392057766345, "Intentional product use issue ": 8.626283045552423, "Intestinal obstruction ": 3.0566396679970795, "Intracranial pressure increased ": 9.021462063065089, "Iridocyclitis ": 12.17139752720167, "Laryngeal oedema ": 3.5443050167870074, "Lip oedema ": 4.096246433612609, "Liver function test increased ": 2.334919296695529, "Lymphopenia ": 3.783710496363629, "Macular oedema ": 18.16314842919592, "Malignant melanoma ": 5.734243465443444, "Metastases to central nervous system ": 16.145387217005425, "Metastasis ": 15.896274964634316, "Metastatic malignant melanoma ": 15.604456715116802, "Mucosal inflammation ": 8.15032580005422, "Ocular toxicity ": 93.4614007033173, "Off label use ": 2.1227006688595136, "Pancreatitis acute ": 2.198002288287974, "Panniculitis ": 34.98819975996297, "Photosensitivity reaction ": 48.65962371824853, "Pneumonitis ": 2.678370267489312, "Purpura ": 7.653219576577805, "Rash ": 5.313415021004291, "Rash erythematous ": 3.0379560305764066, "Rash macular ": 3.698550424992341, "Rash maculo-papular ": 18.955030211616936, "Rash morbilliform ": 3.659702749891444, "Rash papular ": 6.08799769093459, "Rash pustular ": 11.840390810471607, "Renal failure ": 2.4691754387645224, "Retinal detachment ": 15.115697027713354, "Retinal vein occlusion ": 12.765318213638976, "Retinopathy ": 14.781719428488843, "Rhabdomyolysis ": 5.010526842130283, "Sarcoidosis ": 8.190375012864958, "Sepsis ": 2.101910402749798, "Serous retinal detachment ": 107.21847583932563, "Serous retinopathy ": 409.36206245802754, "Skin exfoliation ": 5.075520784789844, "Skin lesion ": 2.48213174438987, "Skin reaction ": 5.304706672132148, "Skin toxicity ": 64.83311325050242, "Solar dermatitis ": 156.49582911159865, "Stevens-Johnson syndrome ": 10.40663698851975, "Stomatitis ": 4.336394529183146, "Sunburn ": 17.956077288190652, "Systemic inflammatory response syndrome ": 12.000473504775988, "Toxic epidermal necrolysis ": 2.310534855042937, "Toxic skin eruption ": 17.50779306578391, "Transaminases increased ": 4.383722364188557, "Uveitis ": 32.431906243672366}
\ No newline at end of file
+{"Blood pressure increased": 7.091434318123971, "Oedema peripheral": 11.175062427395575, "Wrong technique in product usage process": 24.675147702071957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/3.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/3.json
index 409fdfe0a12..5599a442cd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/3.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/3.json
@@ -1 +1 @@
-{"Accidental underdose ": 181.5460973674148, "Blood glucose abnormal ": 67.53836703459412, "Blood glucose decreased ": 19.4507735038502, "Blood glucose fluctuation ": 29.97973339863641, "Blood glucose increased ": 36.43872731950109, "Device malfunction ": 2.7363928615479134, "Diabetes mellitus inadequate control ": 13.576814997310883, "Drug hypersensitivity ": 2.5685925801274303, "Drug ineffective ": 2.380551933999816, "Feeling abnormal ": 2.0872196196020334, "Flatulence ": 2.3712220495380154, "Glycosylated haemoglobin increased ": 46.47747577782364, "Hyperglycaemia ": 16.96847515543729, "Hyperinsulinaemic hypoglycaemia ": 65.58767067997874, "Hypoglycaemia ": 27.4716490677543, "Hypoglycaemic coma ": 9.719689281518743, "Incorrect dose administered ": 26.08744557641807, "Incorrect product administration duration ": 7.1564066121743215, "Increased appetite ": 4.18889015468786, "Injection site bruising ": 11.780928036942004, "Injection site erythema ": 2.1638517789902854, "Injection site haematoma ": 2.4163040735604557, "Injection site haemorrhage ": 19.351303492751885, "Injection site mass ": 10.178046675029629, "Injection site pain ": 5.027834730728956, "Injection site pruritus ": 4.789358893265909, "Injection site rash ": 7.09270767931323, "Injection site reaction ": 2.407472071824382, "Injection site urticaria ": 8.595450092692062, "Injury associated with device ": 22.5503474954124, "Ketoacidosis ": 6.167752790524029, "Lipodystrophy acquired ": 8.842062201004781, "Nocturia ": 5.710478804883988, "Pancreatic carcinoma ": 2.1075353199285973, "Product administration error ": 2.476840969105917, "Product dose omission issue ": 6.9774223695475, "Product storage error ": 17.368902802593887, "Product substitution issue ": 7.750088083341915, "Pruritus ": 2.934934147561611, "Rash pruritic ": 2.645049380968972, "Skin reaction ": 2.0084283033524843, "Therapeutic response unexpected ": 27.087702835363736, "Visual impairment ": 3.506080805167576, "Weight decreased ": 2.27398926473085, "Weight increased ": 4.88030913240921, "Wound ": 2.4510006868617524, "Wrong product administered ": 12.477415229121013, "Wrong technique in product usage process ": 2.684229180269249}
\ No newline at end of file
+{"Abdominal lymphadenopathy": 13.045411982848195, "Abdominal mass": 4.55206955826119, "Acute abdomen": 4.209149135288143, "Adjustment disorder with depressed mood": 4.237392635996414, "Asthma": 11.18705619156061, "Atypical mycobacterial infection": 6.40049620029478, "Autoimmune disorder": 2.074002188302761, "Back pain": 4.389003158639491, "Blood HIV RNA increased": 25.67870412641772, "Blood bicarbonate decreased": 2.735628081751657, "Blood cholesterol increased": 2.265947060175652, "Blood lactic acid increased": 5.990125632948553, "Blood triglycerides increased": 4.88779787963303, "Bone erosion": 4.959304350083734, "Breast abscess": 8.032117069749779, "Breast cancer stage II": 9.520238510807271, "Bursitis": 47.20459823749535, "CD4 lymphocytes abnormal": 25.96849687412544, "CD4 lymphocytes decreased": 16.693340216124966, "CSF HIV escape syndrome": 21.08616618887081, "Cachexia": 5.432932494579837, "Cardiothoracic ratio increased": 92.33324993520672, "Cerebral toxoplasmosis": 15.375319019851752, "Chorea": 3.7998022292620703, "Coeliac disease": 79.09586377480385, "Constipation": 6.056210504784032, "Contraindicated product administered": 12.615542890687712, "Contrast media allergy": 16.890621327361735, "Cryptosporidiosis infection": 40.31127095948433, "Cytomegalovirus chorioretinitis": 8.867005244954214, "Cytomegalovirus oesophagitis": 27.96341927510422, "Decreased immune responsiveness": 21.23767603914714, "Depressive symptom": 2.340914897702409, "Diplopia": 5.919992515891461, "Disseminated mycobacterium avium complex infection": 69.60096594591275, "Drug hypersensitivity": 8.931655246947033, "Drug intolerance": 9.14315800120726, "Drug level below therapeutic": 2.100719136037982, "Drug resistance": 8.986599769085734, "Dysdiadochokinesis": 17.0516850194585, "Dyslipidaemia": 10.37914977592417, "Erythema": 3.14560439492838, "Exposure during pregnancy": 21.520575829574344, "Eyelid ptosis": 22.46328883559437, "Facial wasting": 31.997446216782944, "Fanconi syndrome": 4.361520189598277, "Fat redistribution": 54.17487555254509, "Fat tissue increased": 12.454398859117411, "Fluid retention": 33.842645036699935, "Foetal death": 125.86364401362368, "Food allergy": 240.7774194936877, "Genotype drug resistance test positive": 4.022235736866002, "Glucose tolerance impaired": 5.069443730099772, "Glycosuria": 3.383961996854826, "HIV infection": 12.6857707366339, "HIV-associated neurocognitive disorder": 40.65245686934084, "Hepatic cirrhosis": 2.746889785944175, "Hepatic enzyme increased": 16.164598524776167, "Hepatic necrosis": 2.747350681839932, "Hepatosplenomegaly": 4.62450283413216, "High density lipoprotein decreased": 4.3398256019239785, "Hyperbilirubinaemia": 2.189000727463703, "Hypercholesterolaemia": 2.5043014690160077, "Hyperhidrosis": 6.291607386652432, "Hyperlactacidaemia": 6.503108083219105, "Hyperphagia": 3.801172835424252, "Hypersensitivity": 6.378976133651239, "Hypertension": 5.586330303197478, "Hypertriglyceridaemia": 5.814932666104827, "Hypophosphataemia": 3.717831182234173, "Ileal ulcer": 9.03149706490749, "Immune reconstitution inflammatory syndrome": 17.352714529019355, "Immunodeficiency": 161.58609277409082, "Impetigo": 8.154383034073085, "Infection": 8.592568638456447, "Infusion related reaction": 24.46678274043601, "Intentional product misuse": 15.989563109724989, "Intra-abdominal haematoma": 4.193291201577518, "Joint swelling": 12.71982779552135, "Kaposi's sarcoma": 9.935784191756234, "Lactic acidosis": 2.256909516030749, "Lip discolouration": 8.50009195042409, "Lip erosion": 8.871796013938816, "Lipids abnormal": 10.272007388770064, "Lipoatrophy": 46.42425179826252, "Lipodystrophy acquired": 65.03054498160915, "Lipoedema": 18.16045255675414, "Live birth": 2.278848749431539, "Low density lipoprotein increased": 6.529795958369237, "Lymphoedema": 2.0673110052091954, "Magnetic resonance imaging head abnormal": 3.2284729614290035, "Maternal exposure before pregnancy": 6.627569793842597, "Maternal exposure during pregnancy": 3.212953764124815, "Meningitis viral": 7.782808416034403, "Metastatic malignant melanoma": 2.146734443215766, "Mitochondrial cytopathy": 15.408894107948033, "Mitochondrial myopathy": 154.91757398474897, "Mitochondrial toxicity": 169.22159041294174, "Multiple-drug resistance": 9.396463745113849, "Muscle haemorrhage": 3.1421042455548305, "Mycobacterium avium complex infection": 4.033079831110975, "Mycobacterium test positive": 28.265747711225867, "Nail discolouration": 3.662884932648735, "Nephropathy toxic": 2.357228084229724, "Neurological symptom": 2.1239278787773963, "Obliterative bronchiolitis": 13.102626038528143, "Oesophageal candidiasis": 9.745763986665612, "Off label use": 2.468247030307359, "Ophthalmoplegia": 5.394833940515004, "Oral candidiasis": 2.075965350732973, "Osteochondrosis": 7.523871228005273, "Overdose": 8.134701076405351, "Pain": 2.1754338099184727, "Pathogen resistance": 30.04171271939711, "Pelvic inflammatory disease": 12.334426810172763, "Pneumocystis jirovecii infection": 7.609767410855049, "Polymerase chain reaction": 44.75061526696715, "Portal hypertension": 4.956103283268751, "Premature labour": 2.6015549874251267, "Prescribed overdose": 53.5035246367101, "Product use issue": 11.108501861523091, "Progressive external ophthalmoplegia": 1506.060606607389, "Progressive multifocal leukoencephalopathy": 4.986634574696754, "Psoriasis": 22.82069497717423, "Pulmonary tuberculosis": 4.683215957035845, "Rash": 2.7714375763811026, "Rash erythematous": 24.002935111778584, "Renal function test abnormal": 2.818740823808979, "Renal hypoplasia": 24.746920393446317, "Renal tubular dysfunction": 4.546955439109031, "Rheumatoid arthritis": 13.68568399991304, "Sleep terror": 2.150067382438213, "Superinfection bacterial": 23.86035221745633, "Susac's syndrome": 65.91390191458981, "Temperature regulation disorder": 188.0771604736076, "Thrombocytopenia": 7.725091163101422, "Toxoplasmosis": 6.091908032087636, "Treatment failure": 15.659686250359382, "Treatment noncompliance": 5.69494683181208, "Upper respiratory tract infection": 68.09805521754512, "Urine abnormality": 2.0456032338440244, "Varicocele": 16.96637215021089, "Viraemia": 8.725279691354764, "Viral load increased": 4.006606114955514, "Viral mutation identified": 77.8069111877787, "Virologic failure": 50.577737318825946}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/30.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/30.json
index 323fd44ddf9..1c2fc1f1a06 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/30.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/30.json
@@ -1 +1 @@
-{"Activated partial thromboplastin time abnormal ": 374.1761842739554, "Acute coronary syndrome ": 13.710295525165574, "Acute kidney injury ": 10.818448560387464, "Acute myocardial infarction ": 2.3601018908115656, "Agranulocytosis ": 5.867633198958331, "Angina unstable ": 15.484833348324916, "Aortic arteriosclerosis ": 23.49110535832396, "Ascites ": 2.188161820677574, "Atrial fibrillation ": 3.249946301836666, "Benign prostatic hyperplasia ": 13.099471940821651, "Blood bilirubin abnormal ": 53.82988560392123, "Blood creatine phosphokinase increased ": 3.2755392050165577, "Blood glucose abnormal ": 4.063265812431441, "Cardiac failure ": 3.3822210632874974, "Cerebral haemorrhage ": 2.6200366421881203, "Cholestasis ": 5.40001376007055, "Dermatitis bullous ": 6.514832155554581, "Dermatitis exfoliative generalised ": 7.674214458958129, "Diarrhoea ": 2.184277298427641, "Eosinophilia ": 4.997639530733817, "Gamma-glutamyltransferase increased ": 2.2324113750861883, "Gout ": 45.30652748015892, "Haematocrit abnormal ": 84.86288409180669, "Haematocrit decreased ": 3.660531441984818, "Haemoglobin abnormal ": 17.513713306348304, "Haemoglobin urine present ": 553.1129733142666, "Hepatic cyst ": 24.891713854811687, "Hepatic cytolysis ": 5.323263611438191, "Hepatic lesion ": 16.33422370365732, "Hiatus hernia ": 5.58467613474207, "Hyperkalaemia ": 9.7812557148707, "Hypertriglyceridaemia ": 9.960953698040502, "International normalised ratio abnormal ": 47.30346194139375, "Lactic acidosis ": 5.490190426958176, "Liver function test abnormal ": 2.564100772432423, "Lordosis ": 180.51049166018075, "Lung opacity ": 13.713146368286308, "Mean cell haemoglobin increased ": 64.78516098067134, "Mean cell volume increased ": 47.9568886855016, "Mesenteric vein thrombosis ": 46.56288698766726, "Metastases to soft tissue ": 223.2416131666521, "Nasal congestion ": 6.067665667193415, "Oedema peripheral ": 2.746627518993653, "Osteochondrosis ": 71.51681785343544, "Osteolysis ": 49.3448447442696, "Osteoma ": 508.8565670154496, "Pancreatitis ": 2.142315086416051, "Pancreatitis acute ": 6.241606018796652, "Pancytopenia ": 4.301883514820562, "Photosensitivity reaction ": 3.5830813384944955, "Platelet count abnormal ": 17.25268611390025, "Polycystic liver disease ": 1213.679415045924, "Prostatic specific antigen abnormal ": 133.27292678749092, "Prothrombin time abnormal ": 250.0058291022553, "Pruritus ": 3.276291395375459, "Rash ": 2.000683397842741, "Rash macular ": 2.622158722603908, "Rash maculo-papular ": 2.9882795692359645, "Red blood cell abnormality ": 75.9988236208984, "Red blood cell count decreased ": 3.826591863159615, "Red blood cells urine positive ": 109.25715683691053, "Renal failure ": 2.572935342165042, "Renal impairment ": 2.392078854808924, "Rhabdomyolysis ": 5.0221998599265705, "Scoliosis ": 13.97655697077372, "Sensory disturbance ": 2.8412808358131, "Shock haemorrhagic ": 11.700086132993825, "Skin exfoliation ": 3.1840999384873645, "Spinal osteoarthritis ": 10.772252213981892, "Splenic cyst ": 480.0525267081996, "Splenic lesion ": 237.83925840689983, "Splenic necrosis ": 943.002815407432, "Stevens-Johnson syndrome ": 2.026528621078504, "Sudden death ": 4.778796087495595, "Toxic epidermal necrolysis ": 2.740091497767901, "Toxic skin eruption ": 3.766647909585721, "Transaminases increased ": 3.5150908868305195, "Transient ischaemic attack ": 2.181374642818948, "Troponin increased ": 11.78349675767964, "Tubulointerstitial nephritis ": 7.123455241857869, "Underdose ": 5.751806739494086, "Urinary sediment present ": 206.91405336777973, "White blood cells urine positive ": 59.34975512620794, "Wrong technique in product usage process ": 5.087540655383932}
\ No newline at end of file
+{"Abdominal discomfort": 2.095731150133332, "Abdominal distension": 4.511819407257338, "Acute respiratory failure": 3.2624012654356576, "Ascites": 2.994572045662028, "Blood potassium decreased": 3.204998557492243, "Blood pressure abnormal": 5.4355459418869145, "Blood pressure decreased": 5.765103622474488, "Brain natriuretic peptide increased": 18.55263830961768, "Cardiac failure": 2.2209392386324285, "Cardiothoracic ratio increased": 259.63979882364947, "Catheter site erythema": 58.58749674255598, "Catheter site infection": 37.15445880914137, "Clostridium difficile infection": 3.517549486517138, "Complication associated with device": 16.339972209523477, "Concomitant disease aggravated": 10.726858528952008, "Device breakage": 16.9709243175089, "Device related infection": 6.592508650715661, "Diarrhoea": 2.355901929805038, "Drug intolerance": 2.084243444715785, "Dyspepsia": 3.860989987772288, "Dyspnoea": 2.4589805759814074, "Dyspnoea exertional": 12.824523977657682, "Ear discomfort": 3.972356740289452, "Fluid retention": 17.165358852597656, "Flushing": 6.115299737631473, "Gastrooesophageal reflux disease": 5.202931402120904, "Haemoglobin decreased": 2.208148326650264, "Haemoptysis": 3.2755053627031425, "Head injury": 3.407176019874939, "Hospitalisation": 4.697665291767141, "Hypervolaemia": 17.56384877407431, "Hypotension": 6.084132914511892, "Hypoxia": 3.897665608226816, "Infusion site erythema": 21.72114957276768, "Infusion site infection": 120.68576651036204, "Infusion site pain": 51.3638777441586, "Infusion site pruritus": 52.15594348002582, "Infusion site reaction": 31.05025116633616, "Infusion site swelling": 34.219016949031506, "Iron deficiency anaemia": 12.12754623459814, "Nasal congestion": 6.332022762905129, "Oedema": 5.30380729086785, "Oedema peripheral": 4.540137349250328, "Oliguria": 6.724281081010858, "Oxygen saturation decreased": 9.6793301010186, "Pain in jaw": 33.97084848612666, "Pericardial effusion": 3.158395033791112, "Product dose omission issue": 3.0888796361810225, "Productive cough": 2.4414356644276016, "Pulmonary arterial hypertension": 42.91335308582476, "Pulmonary hypertension": 15.367376900273689, "Pulmonary oedema": 2.947523623401387, "Purpura": 2.712762989969136, "Radiation pneumonitis": 54.69337486707991, "Respiratory failure": 2.543170700643128, "Retching": 2.6671319913359435, "Right ventricular failure": 34.15061787427038, "Sickle cell anaemia with crisis": 15.43620096209162, "Skin discolouration": 2.2127222165957288, "Therapy non-responder": 3.9233843042512255, "Thyroid mass": 14.75452783090638, "Transfusion": 7.489274457862896, "Treatment noncompliance": 2.185169553759043, "Unevaluable event": 7.043618286334845, "Upper respiratory tract inflammation": 42.805849628433954, "Uterine haemorrhage": 9.06019176767264, "Vascular device infection": 14.688126258422871, "Weight fluctuation": 14.526967068293562, "Weight increased": 2.596112598162445}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/300.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/300.json
index f3e0ab80967..f77ea6a26bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/300.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/300.json
@@ -1 +1 @@
-{"Acetonaemic vomiting ": 4.546024796603692, "Achenbach syndrome ": 4.4596667087219055, "Adverse event following immunisation ": 6.096755654613295, "Analgesic drug level ": 7.125327741332961, "Aortic embolus ": 11.339416126085275, "Application site bruise ": 2.14016194061601, "Application site pain ": 10.221302054320926, "Application site reaction ": 5.012030946021421, "Application site swelling ": 4.9708971392042685, "Arthralgia ": 3.656683919396985, "Asthenopia ": 4.21908167496616, "Bacille Calmette-Guerin scar reactivation ": 3.08879576801702, "Blood glucose ": 4.083143474442781, "Blood iron ": 7.9770953345728195, "Blood pH ": 13.840275549514487, "Blood pressure measurement ": 4.830527799155113, "Blood test ": 3.60503979279196, "Blue toe syndrome ": 2.248405392731321, "Body temperature ": 25.14779783555042, "Body temperature abnormal ": 6.409983627235924, "Body temperature fluctuation ": 3.963407861483574, "Body temperature increased ": 2.7458390831097987, "Burning feet syndrome ": 2.9877618189352444, "Cavernous sinus thrombosis ": 2.262719745072532, "Cerebral venous sinus thrombosis ": 3.9754885833761295, "Chest crushing ": 4.288963038675858, "Chillblains ": 2.105023455263645, "Chills ": 5.88157733035379, "Cluster headache ": 10.246807404489584, "Cold sweat ": 2.868780119539569, "Cold-stimulus headache ": 8.141540000771561, "Computerised tomogram head ": 6.657436399885064, "Constricted affect ": 2.946861043036056, "Contusion ": 2.257302088104975, "Coronavirus test ": 37.84405664697479, "Delirium febrile ": 3.1941370078078286, "Dental paraesthesia ": 2.5200432444479546, "Diaphragmalgia ": 2.037056053273354, "Dizziness exertional ": 3.819390747448455, "Dizziness postural ": 7.544912524377589, "Ear pain ": 3.2423851859932724, "Eye pain ": 3.7386778630514574, "Eyelid cyst ": 2.840982603901688, "Fatigue ": 3.042111429090786, "Feeling cold ": 5.273478989088326, "Feeling of body temperature change ": 4.0782337138209375, "Fibrin D dimer increased ": 3.792462431233144, "Food aversion ": 2.65731507528003, "Forced expiratory volume increased ": 3.019958881676571, "Freezing phenomenon ": 7.947572575735706, "Grip strength ": 2.412841223328144, "Guillain-Barre syndrome ": 2.2288497602240107, "Habit cough ": 14.095700905477258, "Hangover ": 3.909260378432904, "Head lag ": 4.564915104349509, "Headache ": 4.419550032644259, "Heart rate ": 28.741196662589243, "Hemiplegic migraine ": 3.035055365627608, "Hepatic vein thrombosis ": 2.0267785406476344, "Hot flush ": 2.05211389701345, "Hyperhidrosis ": 2.775170598643258, "Hypopnoea ": 2.1231020009038053, "Illness ": 2.2854850539468843, "Immunology test ": 4.154594980138139, "Influenza ": 2.3904406625988543, "Influenza like illness ": 6.182112025594535, "Injection ": 4.504651426038966, "Injection related reaction ": 20.9037203314345, "Injection site deformation ": 2.3496774879422597, "Injection site haematoma ": 2.678747897529838, "Injection site inflammation ": 3.53590516428511, "Injection site joint erythema ": 2.198008132860444, "Injection site joint pain ": 2.3221512869589893, "Injection site joint swelling ": 3.2573999382393377, "Injection site mass ": 4.811952951021213, "Injection site pain ": 2.4085417306501555, "Injection site swelling ": 2.0514718606525166, "Injection site warmth ": 3.0707008169526326, "Instillation site warmth ": 5.130234219942129, "Ischaemic limb pain ": 2.8988850749334607, "Labyrinthitis ": 3.237443169633215, "Lacunar stroke ": 3.165761276987318, "Lethargy ": 3.247695603471658, "Limb immobilisation ": 2.1169363616894614, "Lumbar puncture ": 2.040083672172359, "Magnetic resonance imaging head ": 10.051137178476331, "Malaise ": 2.622014177443229, "Maternal exposure during breast feeding ": 7.676688074161753, "Menstruation delayed ": 2.80655562536948, "Mental fatigue ": 6.039446641253501, "Migraine ": 3.8096253557000335, "Migraine with aura ": 3.545596431366792, "Miliaria ": 4.115383950897705, "Motion sickness ": 3.0262720549873903, "Mouth cyst ": 3.784728824037096, "Muscle fatigue ": 9.133361587542094, "Myalgia ": 4.35125107258701, "Myelitis transverse ": 2.0446528978229708, "Myocardial strain imaging ": 7.037313775342047, "Nausea ": 2.5382042689332804, "Neck pain ": 2.3557841345100403, "New daily persistent headache ": 2.359385446581346, "Night sweats ": 2.557843516538353, "No reaction on previous exposure to drug ": 2.484105469062831, "Oral blood blister ": 3.211326033890387, "Oral contusion ": 2.533624472913047, "Oropharyngeal pain ": 2.3067672486762474, "Oversensing ": 4.700049216497536, "Pain in extremity ": 2.674247190492264, "Pain of skin ": 3.1204990500754066, "Paroxysmal extreme pain disorder ": 5.064751622687733, "Pelvic haemorrhage ": 3.6600657481491448, "Periarthritis ": 4.958457251061391, "Peripheral coldness ": 3.0870732450579337, "Persistent postural-perceptual dizziness ": 5.760710746971374, "Photophobia ": 2.552377572771684, "Piloerection ": 2.654475626836231, "Postmenopause ": 3.768192100120235, "Pregnancy test ": 29.767113554509702, "Primary headache associated with sexual activity ": 4.301706552270272, "Primary stabbing headache ": 12.462343133790666, "Procedural dizziness ": 6.910463954165801, "Prophylaxis of nausea and vomiting ": 13.78494150559252, "Pulmonary pain ": 2.6820752201189526, "Puncture site bruise ": 14.377338801613528, "Puncture site pain ": 2.066090346390676, "Pyrexia ": 4.326730597626697, "Q fever ": 11.21102624713178, "Radiculitis brachial ": 2.411832928514144, "Renal pain ": 3.278995172710572, "Respiratory rate ": 4.4596667087219055, "Retinal migraine ": 15.30924681327344, "SARS-CoV-2 test ": 3.259277327040506, "Sensitive skin ": 3.955656354555195, "Shoulder injury related to vaccine administration ": 3.5282621207683795, "Sight disability ": 2.3499647379914945, "Sinus headache ": 15.0152226575333, "Sinus pain ": 7.26351454259773, "Skin sensitisation ": 2.860137711692208, "Skin temperature ": 33.85643489306975, "Skin warm ": 2.413661523246591, "Splenic artery thrombosis ": 2.8840153025405595, "Splenic vein thrombosis ": 2.015084299210519, "Stiff leg syndrome ": 3.630344785372946, "Superficial vein thrombosis ": 2.2674037620261056, "Sweating fever ": 39.36730344655792, "Tenderness ": 4.954230555865419, "Tension headache ": 8.27176381159892, "Thermal burns of eye ": 2.36706499947388, "Thirst ": 2.911761147645873, "Thrombosis with thrombocytopenia syndrome ": 2.1160238036492616, "Thunderclap headache ": 4.888028137089519, "Tinnitus ": 2.1464201427422176, "Tremor ": 2.5485498019064483, "Typical aura without headache ": 3.39022668643998, "Urine output ": 12.697824195159772, "Vaccination site bruising ": 2.9013942815098024, "Vaccination site discomfort ": 2.2753532858299885, "Vaccination site infection ": 2.329395706370232, "Vaccination site inflammation ": 4.935643704645565, "Vaccination site joint erythema ": 2.458281015355784, "Vaccination site joint pain ": 2.252833548782102, "Vaccination site mass ": 4.190805210094067, "Vaccination site pain ": 2.3106827761968924, "Vaginal cyst ": 3.1231704019232844, "Vascular headache ": 12.218704716301591, "Vascular pain ": 2.788624026274165, "Vestibular migraine ": 3.306951015282894, "Viral pharyngitis ": 2.3885315379525798, "Viral rash ": 2.3061088247620534, "Visceral venous thrombosis ": 6.880848315192607, "Vomiting projectile ": 2.492063343113202, "Vulval haemorrhage ": 5.1074949117251975, "White blood cell count ": 2.364097095826074}
\ No newline at end of file
+{"Diabetes mellitus inadequate control": 10.698443351435952, "Drug interaction": 2.007912312744033, "Drug resistance": 18.7736168755498, "Exposure during pregnancy": 5.332542457265976, "Hyperglycaemia": 5.6333498978372845, "Hypoglycaemia": 4.246334857826197, "Neutropenia": 4.311842934995942, "Sepsis": 3.512223488524526, "Tendon rupture": 43.48819364805213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/301.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/301.json
index c253602f131..e78667f0a2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/301.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/301.json
@@ -1 +1 @@
-{"Middle insomnia ": 160.24441423630603}
\ No newline at end of file
+{"Ammonia increased": 66.1559910842339, "Atrioventricular block": 26.20967723560282, "Blood glucose increased": 3.979184796112179, "Drug ineffective": 2.864629538587072, "Electrocardiogram QT prolonged": 6.182824181576268, "Extrapyramidal disorder": 17.00860541866718, "Heart rate decreased": 10.77143943380814, "Hyperglycaemia": 5.122187241592768, "Maternal exposure during pregnancy": 4.2380256575224085, "Premature delivery": 22.918067778130204, "Presyncope": 4.854771962447388, "Sepsis": 2.982044049604561, "Tendon rupture": 38.47378654180518, "Therapeutic product effect decreased": 6.573842814511015}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/302.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/302.json
index d9ca941e7bd..d48bea2cad7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/302.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/302.json
@@ -1 +1 @@
-{"Aspergillus infection ": 37.95264855299348, "Blood creatinine increased ": 4.09909814621109, "Condition aggravated ": 2.567041428096967, "Death ": 8.913182427818843, "Disease progression ": 3.372544881813689, "Drug level below therapeutic ": 67.31762036114814, "Drug level increased ": 7.179809644930304, "Drug-induced liver injury ": 4.101443683140849, "Dysphagia ": 2.064852560599768, "Febrile neutropenia ": 9.188030188132352, "Fungal infection ": 9.34074022540293, "Gamma-glutamyltransferase increased ": 5.037255494651044, "Hallucination ": 2.2399277868072978, "Hepatic cytolysis ": 4.711618031890461, "Hepatic enzyme increased ": 2.8910810707256016, "Hepatotoxicity ": 6.758688786864178, "Infection ": 2.545807893418941, "Infusion site irritation ": 535.8320072993289, "Intentional product use issue ": 5.304643833263192, "Leukaemia ": 15.208481165981857, "Mucormycosis ": 52.345649742807865, "Multiple organ dysfunction syndrome ": 4.9517323139424425, "Off label use ": 8.538628319442514, "Phlebitis ": 18.152061890242305, "Product administered to patient of inappropriate age ": 27.39448415324466, "Respiratory failure ": 2.507764200291, "Severe cutaneous adverse reaction ": 2531.003005491023, "Transaminases increased ": 5.771880817934807}
\ No newline at end of file
+{"Abscess": 2.524814693191307, "Abscess limb": 4.362661541755544, "Accidental exposure to product": 7.90980797807932, "Accidental underdose": 2.3273615147069857, "Acne": 2.2420718819795584, "Acrochordon": 12.093647424940576, "Actinic keratosis": 5.070433960298786, "Acute febrile neutrophilic dermatosis": 3.2904849637895905, "Adenocarcinoma of colon": 2.968428628449614, "Adjustment disorder with depressed mood": 2.1066981637073896, "Amyotrophic lateral sclerosis": 2.4919692264470825, "Anal abscess": 2.237241184053005, "Ankylosing spondylitis": 42.781363356957634, "Antinuclear antibody increased": 6.424361254158723, "Aphthous ulcer": 4.291678194167765, "Arthritis": 5.9382700498600665, "Arthritis bacterial": 3.3910701691494656, "Arthrodesis": 19.10659964237278, "Arthropathy": 3.758900560676495, "Arthropod bite": 2.004346349618986, "Back pain": 2.3467966998553584, "Bacterial vaginosis": 14.327199733125411, "Basal cell carcinoma": 2.151731973172077, "Behcet's syndrome": 5.470506667279473, "Blepharitis": 2.2482182870361287, "Blood albumin decreased": 2.155060679856436, "Blood pressure diastolic decreased": 2.3686340864424222, "Blood pressure systolic increased": 3.157968965602352, "Body temperature decreased": 3.9650994525633863, "Bone erosion": 4.227226735705486, "Bone lesion": 4.527553107609191, "Bone marrow oedema": 13.254715579195745, "Bowel movement irregularity": 4.891320879776164, "Bronchitis": 2.570809115335168, "Bursitis": 3.793975043341068, "C-reactive protein": 4.418592796998129, "C-reactive protein abnormal": 3.943446657013221, "C-reactive protein increased": 4.868557121930645, "Candida infection": 6.043343837621177, "Cellulitis": 3.469181205967024, "Chest injury": 6.308259138711324, "Chronic disease": 23.989746821421907, "Colitis": 3.491534338896641, "Colitis microscopic": 4.076171958929578, "Colitis ulcerative": 6.0175547758444194, "Concomitant disease aggravated": 8.247259170029082, "Concomitant disease progression": 2.953300188422351, "Conjunctivitis": 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leakage": 5.1105172906562055, "Device malfunction": 3.2657881724918263, "Diarrhoea haemorrhagic": 4.5647714075403885, "Discomfort": 2.144955012412693, "Dislocation of vertebra": 3.810563179262849, "Diverticulitis": 2.803880264247209, "Drug dose omission by device": 6.133042607560538, "Drug effect less than expected": 3.036140445235973, "Drug hypersensitivity": 2.332927024009367, "Drug ineffective": 3.4738936648205097, "Drug intolerance": 3.5871608358189357, "Dry eye": 2.0693219926019624, "Dry skin": 3.166996232207971, "Duodenal ulcer perforation": 2.06391950965014, "Dyshidrotic eczema": 8.780519613064982, "Ear disorder": 4.0560639710679, "Ear infection": 2.9943960835692565, "Ear injury": 27.181806342717657, "Ear neoplasm": 66.06622112394976, "Ear pruritus": 3.072413069175808, "Early satiety": 9.070353027620046, "Eczema": 3.6484207690903614, "Endometriosis": 2.553011241533464, "Enteritis": 3.3080518573333944, "Enthesopathy": 39.07571443489129, "Epicondylitis": 4.006872857572628, 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"Spondylitis": 13.97751363211443, "Spondyloarthropathy": 8.457833616332053, "Sputum discoloured": 2.1678719353245373, "Squamous cell carcinoma": 2.150638860495261, "Staphylococcal infection": 3.351852285539036, "Staphylococcal skin infection": 8.739475723841249, "Staphylococcus test positive": 2.729073734551345, "Streptococcal infection": 2.281724282651118, "Stress": 2.981237339622082, "Subcutaneous abscess": 4.775363978644431, "Sunburn": 3.0919574755562618, "Swollen joint count": 193.83357637369545, "Swollen joint count increased": 6.278772036764746, "Symptom recurrence": 9.197166413769205, "Synovial cyst": 4.072452326504733, "Synovial disorder": 20.434474237501384, "Synovitis": 6.592732543177906, "Syringe issue": 2.7146593513551784, "Telangiectasia": 6.602495231288865, "Temporomandibular pain and dysfunction syndrome": 5.053846143796851, "Tender joint count": 190.2143425005944, "Tenderness": 3.23350390646102, "Tendon disorder": 3.133870211518992, "Tendonitis": 2.471719031473881, "Tenosynovitis": 14.284530705870417, "Terminal insomnia": 7.883606564674112, "Therapeutic product effect decreased": 4.675367917473597, "Therapeutic product effect delayed": 2.424430818196534, "Therapeutic product effect incomplete": 5.3307788851486695, "Therapeutic response decreased": 2.2244423532937376, "Therapeutic response shortened": 21.36423355476603, "Therapy non-responder": 3.6048130334570425, "Tinea pedis": 21.981137076329155, "Tonsillar ulcer": 77.82964788506435, "Tonsillitis": 9.478337018363916, "Tooth abscess": 9.122525205964068, "Treatment failure": 6.40435701662118, "Trismus": 3.138113128319959, "Tuberculin test positive": 4.116555711509889, "Tuberculosis": 4.600115367144682, "Type 2 diabetes mellitus": 2.327116348932031, "Upper respiratory tract infection": 2.805103265915054, "Urticarial vasculitis": 4.272452463009635, "Uveitis": 10.971662889532276, "Vaginal infection": 17.156050856163723, "Vitiligo": 4.256212089187321, "Vulvovaginal candidiasis": 9.736597588498617, "Vulvovaginal mycotic infection": 4.144883740793408, "Wound infection": 2.3424363049293078, "Wound secretion": 5.911723810487288, "Wrong technique in device usage process": 2.8694225534210944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/303.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/303.json
index 77ff91d7b56..707aa67e982 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/303.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/303.json
@@ -1 +1 @@
-{"Abdominal distension ": 3.458816071396651, "Acidosis ": 13.537338732351133, "Acute kidney injury ": 2.3162392171562285, "Alanine aminotransferase increased ": 4.02779829037874, "Amylase increased ": 19.871550489325063, "Anaemia ": 2.761178052670523, "Arterial thrombosis ": 28.06281448725047, "Aspartate aminotransferase increased ": 4.02641241691822, "Bacterial infection ": 3.544951371030247, "Bladder disorder ": 8.516030846607116, "Blood alkaline phosphatase increased ": 3.672133107400042, "Blood bilirubin increased ": 4.582089590566693, "Blood cholesterol increased ": 2.759406209726458, "Blood creatinine increased ": 5.674368572236696, "Blood lactate dehydrogenase increased ": 2.4873491159608374, "Blood lactic acid increased ": 44.87874077578777, "Blood triglycerides increased ": 15.357785872121385, "Blood urea increased ": 9.30572159573579, "Cachexia ": 9.831482652221489, "Calculus urinary ": 66.57269202135188, "Candida infection ": 2.9999920749246627, "Cardiomyopathy ": 6.105403076181301, "Conjunctivitis ": 3.1923777336566554, "Coronary artery disease ": 2.0827210679519155, "Crystalluria ": 193.18415333382933, "Dehydration ": 2.097767668797076, "Diabetes mellitus ": 10.581201166072963, "Diabetic ketoacidosis ": 3.283379577189858, "Diplopia ": 8.567519225773303, "Disseminated intravascular coagulation ": 2.632562002279617, "Drug level changed ": 124.1234648259444, "Drug resistance ": 10.394303020324488, "Dysphagia ": 2.071832252934344, "Dysuria ": 2.561658384609569, "Eyelid ptosis ": 31.305880577446903, "Fat redistribution ": 439.2645132084237, "Flank pain ": 36.12835741627367, "Gamma-glutamyltransferase increased ": 3.876819013571757, "General symptom ": 32.72172983031557, "Haematuria ": 13.637626111973487, "Haemolysis ": 5.218116735602054, "Haemolytic anaemia ": 12.136848413733292, "Haemorrhage intracranial ": 2.776626296418392, "Hepatic cirrhosis ": 4.080061379530517, "Hepatic failure ": 3.5695366402112723, "Hepatic function abnormal ": 2.962430665363821, "Hepatic steatosis ": 8.871254499605044, "Hepatitis ": 6.169405596624159, "Hepatitis cholestatic ": 5.051583375314272, "Hepatomegaly ": 4.296713476066761, "Hydronephrosis ": 74.3874413742463, "Hyperbilirubinaemia ": 21.636897229342207, "Hypercholesterolaemia ": 21.435091590214903, "Hyperglycaemia ": 4.466980246257307, "Hyperlipidaemia ": 13.585619849108884, "Hypertriglyceridaemia ": 78.43224785587607, "Immune reconstitution inflammatory syndrome ": 9.493684024709797, "Ingrowing nail ": 46.29286137177991, "Jaundice ": 5.572587602303014, "Lactic acidosis ": 13.556417406107396, "Lipase increased ": 6.302456072497876, "Lipodystrophy acquired ": 118.34258518135223, "Lipohypertrophy ": 41.87978178834146, "Lymphadenitis ": 4.164586373254649, "Maternal exposure timing unspecified ": 53.1598718254657, "Mitochondrial toxicity ": 171.58590705123788, "Multiple organ dysfunction syndrome ": 2.544399455236729, "Muscle atrophy ": 5.7329972241464535, "Myocardial infarction ": 2.7842469452972254, "Nephrolithiasis ": 108.00935272651444, "Neuropathy peripheral ": 2.899073351509041, "Ophthalmoplegia ": 21.53586652576077, "Osteoarthritis ": 3.286303745960675, "Osteonecrosis ": 2.5995832428780936, "Pancreatitis ": 6.412639307063479, "Pancreatitis acute ": 3.488385110481233, "Pancreatitis necrotising ": 16.038000960695626, "Paronychia ": 31.694505564086292, "Premature baby ": 5.249943410395293, "Progressive external ophthalmoplegia ": 317.3889860292967, "Proteinuria ": 2.752359486201103, "Pyelonephritis ": 6.738935631121545, "Renal colic ": 98.84856729281594, "Renal disorder ": 2.802216345318355, "Renal failure ": 2.749757878233725, "Renal pain ": 13.240787367702504, "Transaminases increased ": 2.010288128843992, "Tubulointerstitial nephritis ": 9.112639918945137, "Type 1 diabetes mellitus ": 4.500700291366508, "Ureterolithiasis ": 74.24484245035234}
\ No newline at end of file
+{"Acne": 3.555496705658454, "Acute kidney injury": 2.278549547279668, "Aphthous ulcer": 5.273353831346296, "Aspartate aminotransferase increased": 2.138368435203255, "Blood alkaline phosphatase increased": 4.519842431229907, "Blood bilirubin increased": 2.102718310832065, "Blood creatine phosphokinase increased": 6.72026706243508, "Blood creatinine increased": 2.293544211276965, "Blood lactate dehydrogenase increased": 4.249604998943078, "Cardiomyopathy": 4.832497607997906, "Central serous chorioretinopathy": 78.12012832584566, "Cholestasis": 11.8751675120925, "Conjunctivitis": 4.028240801491386, "Cytokine release syndrome": 2.0423892588583823, "Death": 3.509511679071972, "Dermatitis": 4.807300347840946, "Dermatitis acneiform": 62.81203508210757, "Dermatitis allergic": 3.560205889772776, "Diarrhoea": 4.079897395510868, "Disease progression": 2.3066045223220164, "Drug reaction with eosinophilia and systemic symptoms": 34.59723030316257, "Ejection fraction decreased": 14.841143333941892, "Electrocardiogram QT prolonged": 2.1219654170119924, "Eosinophilia": 2.8094752618794923, "Erythema multiforme": 3.710378415420109, "Erythema nodosum": 19.465977813204223, "Face oedema": 6.139019589925036, "Folliculitis": 6.105949189442965, "Gamma-glutamyltransferase increased": 2.860585250027473, "Gastritis": 2.358326745641816, "General physical health deterioration": 2.709891744217398, "Hepatic cytolysis": 9.540794144793823, "Hepatitis": 3.553001960603466, "Hepatotoxicity": 3.9147110418945696, "Hyperthermia": 4.8817078958393765, "Hypertransaminasaemia": 5.8447392057766345, "Intentional product use issue": 8.626283045552423, "Intestinal obstruction": 3.0566396679970795, "Intracranial pressure increased": 9.021462063065089, "Iridocyclitis": 12.17139752720167, "Laryngeal oedema": 3.5443050167870074, "Lip oedema": 4.096246433612609, "Liver function test increased": 2.334919296695529, "Lymphopenia": 3.783710496363629, "Macular oedema": 18.16314842919592, "Malignant melanoma": 5.734243465443444, "Metastases to central nervous system": 16.145387217005425, "Metastasis": 15.896274964634316, "Metastatic malignant melanoma": 15.604456715116802, "Mucosal inflammation": 8.15032580005422, "Ocular toxicity": 93.4614007033173, "Off label use": 2.122617006354211, "Pancreatitis acute": 2.198002288287974, "Panniculitis": 34.98819975996297, "Photosensitivity reaction": 48.65962371824853, "Pneumonitis": 2.678370267489312, "Purpura": 7.653219576577805, "Rash": 5.313341900015181, "Rash erythematous": 3.0379560305764066, "Rash macular": 3.698550424992341, "Rash maculo-papular": 18.955030211616936, "Rash morbilliform": 3.659702749891444, "Rash papular": 6.087323806665937, "Rash pustular": 11.840390810471607, "Renal failure": 2.4691754387645224, "Retinal detachment": 15.115697027713354, "Retinal vein occlusion": 12.765318213638976, "Retinopathy": 14.781719428488843, "Rhabdomyolysis": 5.010526842130283, "Sarcoidosis": 8.190375012864958, "Sepsis": 2.101910402749798, "Serous retinal detachment": 107.21847583932563, "Serous retinopathy": 409.36206245802754, "Skin exfoliation": 5.075520784789844, "Skin lesion": 2.48213174438987, "Skin reaction": 5.304706672132148, "Skin toxicity": 64.73812125996253, "Solar dermatitis": 156.49582911159865, "Stevens-Johnson syndrome": 10.40663698851975, "Stomatitis": 4.336394529183146, "Sunburn": 17.956077288190652, "Systemic inflammatory response syndrome": 12.000473504775988, "Toxic epidermal necrolysis": 2.310534855042937, "Toxic skin eruption": 17.50779306578391, "Transaminases increased": 4.383453569365003, "Uveitis": 32.431906243672366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/304.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/304.json
index 506e1de6e02..ff442fd3341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/304.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/304.json
@@ -1 +1 @@
-{"Acquired gene mutation ": 302.8494243972876, "Alanine aminotransferase increased ": 3.899768124345506, "Constipation ": 4.305778310152499, "Dehydration ": 4.8795956723444505, "Disease progression ": 11.146510929790148, "Drug resistance ": 25.86674604070391, "Failure to thrive ": 120.43850822071887, "Gastroenteritis ": 24.71402496274566, "Ileus ": 43.906279563289374, "Malignant neoplasm progression ": 19.025366267636603, "Metapneumovirus infection ": 604.1764313162163, "Metastases to liver ": 15.414354655152296, "Neoplasm malignant ": 7.980252722632817, "Neoplasm progression ": 13.687230092176735, "Neutropenia ": 3.0988208524026764, "Non-small cell lung cancer ": 148.72150343068327, "Oedema peripheral ": 4.112857174936864, "Orthostatic hypotension ": 26.94946694058885, "Pleural effusion ": 5.458902812646247}
\ No newline at end of file
+{"Middle insomnia": 160.24441423630603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/305.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/305.json
index be3d067c1c7..f39682f2a4f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/305.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/305.json
@@ -1 +1 @@
-{"Acute generalised exanthematous pustulosis ": 5.903141674212228, "Acute kidney injury ": 4.063178829203609, "Acute respiratory distress syndrome ": 8.728420295067407, "Acute respiratory failure ": 2.9269676779482365, "Alanine aminotransferase increased ": 2.137439192012651, "Antimicrobial susceptibility test resistant ": 2551.583420968558, "Anuria ": 5.222896514313198, "Aspartate aminotransferase increased ": 3.308233065245218, "Bacteraemia ": 12.68108146363558, "Bacterial infection ": 2.224147029965766, "Blood alkaline phosphatase increased ": 4.006933761777246, "Blood creatine phosphokinase increased ": 54.64423165305575, "Blood creatinine increased ": 3.57564811076335, "C-reactive protein increased ": 2.999257276831506, "Candida infection ": 4.7311635423765965, "Cardiac valve rupture ": 458.9805810301239, "Cardiac valve vegetation ": 323.29525612114486, "Cholestasis ": 2.4078672848134346, "Clostridium difficile colitis ": 7.431467874360369, "Clostridium difficile infection ": 2.3772193634066983, "Computerised tomogram abnormal ": 20.141778659943853, "Creatinine renal clearance decreased ": 4.480271865471554, "Crepitations ": 12.116951230433182, "Cutaneous vasculitis ": 7.300895969521969, "Death ": 2.2522732678909376, "Dermatitis exfoliative generalised ": 4.468505202781701, "Device related infection ": 13.796878362177525, "Disseminated intravascular coagulation ": 5.031266931004899, "Drug eruption ": 3.2501904107130817, "Drug ineffective for unapproved indication ": 9.444749775205455, "Drug reaction with eosinophilia and systemic symptoms ": 10.73023131098096, "Drug resistance ": 11.405141995636962, "Electrocardiogram T wave amplitude decreased ": 66.05628602373844, "Embolism ": 7.065997068771261, "Endocarditis ": 54.16991503955047, "Endocarditis staphylococcal ": 303.4296897289892, "Enterococcal bacteraemia ": 195.76423322614875, "Enterococcal infection ": 45.219181603164905, "Eosinophil count increased ": 23.656250907188188, "Eosinophil percentage increased ": 47.62854443960199, "Eosinophilia ": 32.32341475709163, "Eosinophilic pneumonia ": 682.0369350743701, "Eosinophilic pneumonia acute ": 641.1133176788422, "Extradural abscess ": 43.56351430047237, "Glomerulonephritis acute ": 80.43272265657906, "Haemodialysis ": 10.059418181292155, "Henoch-Schonlein purpura ": 10.959818262048946, "Hepatic cytolysis ": 4.97017628584627, "Hyperbilirubinaemia ": 2.780444514671022, "Hyperkalaemia ": 3.0156361075387403, "Hypersensitivity pneumonitis ": 35.72259692881654, "Hyperthermia ": 3.183789971470352, "Hypertransaminasaemia ": 4.715645780029284, "Hypoxia ": 6.578677513883645, "Hypoxic-ischaemic encephalopathy ": 19.176477140611063, "Infection ": 2.5585112358098008, "International normalised ratio increased ": 2.549046171444755, "Interstitial lung disease ": 5.298761139421984, "Intervertebral discitis ": 21.184428349468572, "Leukopenia ": 2.218182652526236, "Liver function test increased ": 3.858283927757722, "Lung consolidation ": 25.89168983292649, "Lung disorder ": 4.417513773850411, "Lung infiltration ": 36.95154364665658, "Mechanical ventilation ": 9.780774841754138, "Mediastinal abscess ": 237.4138931489093, "Mental status changes ": 3.617554071226496, "Minimum inhibitory concentration ": 685.2128261388098, "Multiple organ dysfunction syndrome ": 8.244554343151947, "Myoglobin blood increased ": 14.917097126754866, "Myopathy ": 14.004946015509192, "Myositis ": 10.66438994533109, "Nephropathy toxic ": 2.8606416350262838, "Organising pneumonia ": 23.709829370286045, "Osteomyelitis ": 21.84415709602437, "Overdose ": 2.4475557792468874, "Pancytopenia ": 3.6665253818099344, "Pathogen resistance ": 54.65440177605538, "Platelet count decreased ": 2.1564889009075965, "Pleural effusion ": 2.292014885393016, "Pneumonitis ": 6.1574672326928725, "Product use in unapproved indication ": 3.8937872325232976, "Prothrombin time prolonged ": 3.18714423285526, "Pulmonary eosinophilia ": 497.9393578332279, "Pulmonary toxicity ": 6.436333795181152, "Purpura ": 2.030812692706112, "Rales ": 3.57432013906676, "Rash maculo-papular ": 2.7879823127235825, "Renal failure ": 2.4700042221524687, "Renal impairment ": 4.283992782238094, "Renal tubular necrosis ": 3.827711585342008, "Respiratory distress ": 2.5035017591251463, "Respiratory failure ": 4.524366199962117, "Rhabdomyolysis ": 29.34515103572772, "Sepsis ": 5.292201549648189, "Septic embolus ": 36.14716161049614, "Septic shock ": 6.954123828398459, "Staphylococcal bacteraemia ": 139.58746271416047, "Staphylococcal infection ": 18.17486335122408, "Staphylococcal sepsis ": 8.457407179613572, "Staphylococcus test positive ": 22.673527040134186, "Status epilepticus ": 2.0710652700024363, "Stevens-Johnson syndrome ": 5.294157804415451, "Systemic candida ": 12.551754928045783, "Systemic inflammatory response syndrome ": 8.867362060286055, "Tachypnoea ": 3.200896137197129, "Thrombocytopenia ": 2.119987646935734, "Toxic epidermal necrolysis ": 4.194768165959792, "Toxic skin eruption ": 8.553486020549041, "Treatment failure ": 4.689950787381013, "Tubulointerstitial nephritis ": 9.117199007140034, "Vancomycin infusion reaction ": 21.82925127112264, "White blood cell count increased ": 3.0048177534827345, "Wound infection staphylococcal ": 30.984574869612715}
\ No newline at end of file
+{"Aspergillus infection": 37.95264855299348, "Blood creatinine increased": 4.09909814621109, "Condition aggravated": 2.567041428096967, "Death": 8.913182427818843, "Disease progression": 3.372544881813689, "Drug level below therapeutic": 67.31762036114814, "Drug level increased": 7.179809644930304, "Drug-induced liver injury": 4.1011936948155725, "Dysphagia": 2.064852560599768, "Febrile neutropenia": 9.188030188132352, "Fungal infection": 9.33814757027215, "Gamma-glutamyltransferase increased": 5.037255494651044, "Hallucination": 2.2399277868072978, "Hepatic cytolysis": 4.711618031890461, "Hepatic enzyme increased": 2.8910810707256016, "Hepatotoxicity": 6.758688786864178, "Infection": 2.545807893418941, "Infusion site irritation": 535.8320072993289, "Intentional product use issue": 5.304643833263192, "Leukaemia": 15.208481165981857, "Mucormycosis": 52.345649742807865, "Multiple organ dysfunction syndrome": 4.9517323139424425, "Off label use": 8.538291712189157, "Phlebitis": 18.152061890242305, "Product administered to patient of inappropriate age": 27.39448415324466, "Respiratory failure": 2.5075571558208924, "Severe cutaneous adverse reaction": 2531.003005491023, "Transaminases increased": 5.7715272582072}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/306.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/306.json
index 94d114bb01f..b7347468809 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/306.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/306.json
@@ -1 +1 @@
-{"Off label use ": 7.277038145070657, "Transaminases increased ": 73.43602230873904}
\ No newline at end of file
+{"Abdominal distension": 3.458816071396651, "Acidosis": 13.537338732351133, "Acute kidney injury": 2.3162392171562285, "Alanine aminotransferase increased": 4.02779829037874, "Amylase increased": 19.871550489325063, "Anaemia": 2.761178052670523, "Arterial thrombosis": 28.06281448725047, "Aspartate aminotransferase increased": 4.02641241691822, "Bacterial infection": 3.544951371030247, "Bladder disorder": 8.516030846607116, "Blood alkaline phosphatase increased": 3.672133107400042, "Blood bilirubin increased": 4.582089590566693, "Blood cholesterol increased": 2.759406209726458, "Blood creatinine increased": 5.674368572236696, "Blood lactate dehydrogenase increased": 2.4873491159608374, "Blood lactic acid increased": 44.87874077578777, "Blood triglycerides increased": 15.357785872121385, "Blood urea increased": 9.30572159573579, "Cachexia": 9.831482652221489, "Calculus urinary": 66.57269202135188, "Candida infection": 2.9999920749246627, "Cardiomyopathy": 6.105403076181301, "Conjunctivitis": 3.1923777336566554, "Coronary artery disease": 2.0827210679519155, "Crystalluria": 193.18415333382933, "Dehydration": 2.097655649369897, "Diabetes mellitus": 10.581201166072963, "Diabetic ketoacidosis": 3.283379577189858, "Diplopia": 8.567519225773303, "Disseminated intravascular coagulation": 2.632562002279617, "Drug level changed": 124.1234648259444, "Drug resistance": 10.394303020324488, "Dysphagia": 2.071832252934344, "Dysuria": 2.561658384609569, "Eyelid ptosis": 31.305880577446903, "Fat redistribution": 439.2645132084237, "Flank pain": 36.12835741627367, "Gamma-glutamyltransferase increased": 3.876819013571757, "General symptom": 32.72172983031557, "Haematuria": 13.637626111973487, "Haemolysis": 5.218116735602054, "Haemolytic anaemia": 12.136848413733292, "Haemorrhage intracranial": 2.776626296418392, "Hepatic cirrhosis": 4.080061379530517, "Hepatic failure": 3.5695366402112723, "Hepatic function abnormal": 2.962430665363821, "Hepatic steatosis": 8.871254499605044, "Hepatitis": 6.169405596624159, "Hepatitis cholestatic": 5.051583375314272, "Hepatomegaly": 4.296713476066761, "Hydronephrosis": 74.3874413742463, "Hyperbilirubinaemia": 21.636897229342207, "Hypercholesterolaemia": 21.435091590214903, "Hyperglycaemia": 4.466980246257307, "Hyperlipidaemia": 13.585619849108884, "Hypertriglyceridaemia": 78.43224785587607, "Immune reconstitution inflammatory syndrome": 9.493684024709797, "Ingrowing nail": 46.29286137177991, "Jaundice": 5.572587602303014, "Lactic acidosis": 13.556417406107396, "Lipase increased": 6.302456072497876, "Lipodystrophy acquired": 118.34258518135223, "Lipohypertrophy": 41.87978178834146, "Lymphadenitis": 4.163623707887661, "Maternal exposure timing unspecified": 53.1598718254657, "Mitochondrial toxicity": 171.58590705123788, "Multiple organ dysfunction syndrome": 2.544399455236729, "Muscle atrophy": 5.7329972241464535, "Myocardial infarction": 2.7842469452972254, "Nephrolithiasis": 107.99090723893724, "Neuropathy peripheral": 2.898985282318922, "Ophthalmoplegia": 21.53586652576077, "Osteoarthritis": 3.286303745960675, "Osteonecrosis": 2.5995832428780936, "Pancreatitis": 6.412639307063479, "Pancreatitis acute": 3.488385110481233, "Pancreatitis necrotising": 16.038000960695626, "Paronychia": 31.694505564086292, "Premature baby": 5.249943410395293, "Progressive external ophthalmoplegia": 317.3889860292967, "Proteinuria": 2.752359486201103, "Pyelonephritis": 6.738935631121545, "Renal colic": 98.84856729281594, "Renal disorder": 2.801802800011008, "Renal failure": 2.749757878233725, "Renal pain": 13.240787367702504, "Transaminases increased": 2.010164994114769, "Tubulointerstitial nephritis": 9.112639918945137, "Type 1 diabetes mellitus": 4.500700291366508, "Ureterolithiasis": 74.24484245035234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/307.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/307.json
index 28c0b3026d2..451bcc89c2a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/307.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/307.json
@@ -1 +1 @@
-{"Completed suicide ": 246.32742747638773}
\ No newline at end of file
+{"Acquired gene mutation": 302.8494243972876, "Alanine aminotransferase increased": 3.899768124345506, "Constipation": 4.305778310152499, "Dehydration": 4.879335223668137, "Disease progression": 11.146510929790148, "Drug resistance": 25.86674604070391, "Failure to thrive": 120.43850822071887, "Gastroenteritis": 24.71402496274566, "Ileus": 43.906279563289374, "Malignant neoplasm progression": 19.025366267636603, "Metapneumovirus infection": 604.1764313162163, "Metastases to liver": 15.414354655152296, "Neoplasm malignant": 7.980252722632817, "Neoplasm progression": 13.687230092176735, "Neutropenia": 3.09868760407131, "Non-small cell lung cancer": 148.72150343068327, "Oedema peripheral": 4.112755538972315, "Orthostatic hypotension": 26.94366211128266, "Pleural effusion": 5.45840026953038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/308.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/308.json
index 7cbe680ed74..ccaee0aa9c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/308.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/308.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 2.5786160897649104, "Abortion spontaneous ": 2.4898774190923567, "Abulia ": 6.353675390827741, "Accidental death ": 3.24561227465808, "Activation syndrome ": 8.636184020815891, "Affect lability ": 98.92737723296162, "Affective disorder ": 2.022214791681776, "Aggression ": 3.440110293971754, "Agitation ": 15.249577262316922, "Agoraphobia ": 4.040936681818285, "Akathisia ": 3.070673060090038, "Alcohol abuse ": 2.2073722859353646, "Alcohol poisoning ": 2.505478527734472, "Alcoholism ": 2.8587493073867547, "Amnesia ": 2.027742381225784, "Anger ": 8.668178873620828, "Angle closure glaucoma ": 5.19229069199196, "Anorgasmia ": 4.295001048573446, "Anovulatory cycle ": 4.885955968575725, "Anticoagulation drug level above therapeutic ": 2.1281337990657474, "Anxiety ": 5.075860392216875, "Anxiety disorder ": 3.199838694786522, "Apathy ": 2.1630539842006167, "Arachnoid cyst ": 5.193343418404978, "Atrophy ": 2.92058461999618, "Auditory disorder ": 2.3927159187112976, "Autoinflammatory disease ": 10.511774389891716, "Bipolar I disorder ": 3.915435412024372, "Bipolar disorder ": 4.076890221810858, "Blood pressure diastolic abnormal ": 4.173067952117106, "Blood pressure diastolic decreased ": 2.4556327824897144, "Blood pressure fluctuation ": 2.1484578939372003, "Blood pressure increased ": 2.0009052009017654, "Blood pressure systolic increased ": 4.311575855696602, "Blood sodium decreased ": 2.3625331151888376, "Blood viscosity increased ": 11.110791152787844, "Body height decreased ": 2.384255670907794, "Brain herniation ": 2.65400827301843, "Bruxism ": 6.947162682775729, "Bursitis ": 2.355285992924158, "Central pain syndrome ": 16.4747193198671, "Cephalo-pelvic disproportion ": 15.580359322997642, "Cholecystectomy ": 2.531439930252384, "Claustrophobia ": 5.069822067101618, "Clonus ": 2.475582041423069, "Colitis microscopic ": 3.81520059694624, "Completed suicide ": 2.1041928351977157, "Complex regional pain syndrome ": 2.1941027618711706, "Concussion ": 3.004044136404002, "Confusional state ": 4.839952156795763, "Conversion disorder ": 3.0508665641081056, "Coordination abnormal ": 2.0035134503138297, "Costochondritis ": 2.7724146591770045, "Crying ": 4.001296338277039, "Cubital tunnel syndrome ": 18.455565138154967, "Decompression sickness ": 177.51824932240976, "Decreased interest ": 2.8800291998215943, "Decreased vibratory sense ": 4.58100827507504, "Delusion ": 2.0827037403405053, "Depressed mood ": 2.3469999876754817, "Depression ": 3.011128459136075, "Depression suicidal ": 2.578171696209027, "Depressive symptom ": 2.208728030161121, "Dermatomyositis ": 2.729272434751405, "Disinhibition ": 2.0494700878486056, "Dissociation ": 2.5603851760607035, "Disturbance in attention ": 2.700552100368536, "Dizziness ": 2.2598958094633668, "Drug interaction ": 2.024751358134939, "Drug screen positive ": 2.321065366623792, "Drug withdrawal headache ": 12.384844739571442, "Drug withdrawal syndrome ": 54.62596448720744, "Dyskinesia ": 2.348201589148452, "Dysphemia ": 2.8788059796859886, "Dysphoria ": 127.10192585752402, "Ectopic pregnancy ": 5.415282170347111, "Ejaculation disorder ": 2.3462500181350947, "Electric shock ": 6.03241675512855, "Electric shock sensation ": 77.96852408160106, "Emotional disorder ": 2.606191721056698, "Emotional poverty ": 5.28290688227006, "Essential tremor ": 8.91189143125125, "Eustachian tube dysfunction ": 4.30131504773034, "Excessive eye blinking ": 2.7490305975551106, "Exfoliative rash ": 3.0694535263777505, "Facial spasm ": 5.82919366512467, "Fall ": 2.174394521463168, "Fear ": 2.494472681394164, "Fear of injection ": 3.275201566018774, "Feeling abnormal ": 2.689952261451072, "Feeling jittery ": 2.266244409233728, "Feeling of despair ": 4.166807949135412, "Fibroadenoma of breast ": 5.000217046436411, "Fibromyalgia ": 3.344752951781586, "Fine motor skill dysfunction ": 3.0600102475698665, "Flat affect ": 3.224675324180957, "Food craving ": 2.7603563031214526, "Gastric bypass ": 16.538125688367607, "Gastrointestinal tube insertion ": 11.168888894371417, "Gastrostomy ": 4.544084198973321, "Generalised anxiety disorder ": 2.8123640446470817, "Glaucoma ": 2.682225518826126, "Glucose urine present ": 5.748010044858063, "Gluten sensitivity ": 9.200053484662345, "Growth hormone deficiency ": 9.343551457553852, "Haemoglobin increased ": 13.606265406869872, "Hallucination ": 2.638617974935465, "Hallucination, auditory ": 2.537637266925037, "Hallucination, visual ": 2.005727838390822, "Hangover ": 4.0590169440219, "Hepatic cirrhosis ": 2.14385500315432, "Hepatic steatosis ": 2.66791333686823, "High density lipoprotein increased ": 4.294792470125227, "Homicidal ideation ": 6.806799998174776, "Homicide ": 2.2442356831622914, "Hostility ": 5.5738376946590815, "Hyperhidrosis ": 4.670875436889571, "Hypermobility syndrome ": 4.413393917948008, "Hyperphagia ": 2.895506825093451, "Hyperreflexia ": 2.518730397239063, "Hypertensive crisis ": 2.5304852945390333, "Hypertonic bladder ": 4.834965793068119, "Hypervigilance ": 4.924775097611434, "Hypokinesia ": 4.018818801496984, "Hypomania ": 58.90137936013216, "Hyponatraemia ": 4.128274806220987, "Hysterectomy ": 4.823055032938819, "Impatience ": 2.9326716628786214, "Implant site extravasation ": 5.432190211167501, "Implant site swelling ": 11.140578576166847, "Impulsive behaviour ": 2.909442587366036, "Inappropriate antidiuretic hormone secretion ": 7.860906762142711, "Incoherent ": 2.408312008833648, "Increased upper airway secretion ": 2.0972793967484766, "Ingrowing nail ": 4.582940686822915, "Insomnia ": 6.038909904020921, "Intentional overdose ": 2.632084065356997, "Intentional product misuse ": 2.6433800547004966, "Intentional self-injury ": 2.070111754560939, "Investigation abnormal ": 6.315578445298536, "Irritability ": 19.78671887651882, "Ischaemic cerebral infarction ": 2.622123333564804, "Joint noise ": 21.74015705043135, "Kidney congestion ": 27.791510508102203, "Laziness ": 3.0491837077550024, "Lethargy ": 6.885095420511219, "Libido decreased ": 3.36527236295115, "Major depression ": 3.3690227382296243, "Mania ": 5.413630572116798, "Medical device site erosion ": 18.672592179462804, "Memory impairment ": 2.846944378320692, "Mental disorder ": 2.241759627222402, "Migraine without aura ": 3.623549546504935, "Mixed anxiety and depressive disorder ": 2.3462935595433465, "Moaning ": 2.68621127695474, "Mood swings ": 23.31086633979196, "Morbid thoughts ": 2.7746362247199667, "Motion sickness ": 2.0720302274388755, "Muscle atrophy ": 4.958690877021871, "Muscle spasticity ": 3.455007319817792, "Muscle tightness ": 3.067953410420849, "Muscle twitching ": 2.088657553373812, "Musculoskeletal pain ": 2.1400790250723007, "Mydriasis ": 6.213169903612969, "Myoclonus ": 2.0798824258018125, "Neck injury ": 2.0705669664758144, "Negative thoughts ": 3.512676521934172, "Nervousness ": 2.1454673488969136, "Nightmare ": 16.040272703168466, "Obsessive thoughts ": 5.034058823718284, "Ocular discomfort ": 4.1623066600193, "Ocular vascular disorder ": 3.61198627754864, "Oesophageal disorder ": 2.346630337097233, "Oesophageal spasm ": 2.8474691023159324, "Open angle glaucoma ": 4.378974673829317, "Ophthalmic vein thrombosis ": 3.824059703848672, "Orgasm abnormal ": 5.169963519201124, "Orthostatic hypotension ": 2.7953874413319744, "Osteoarthritis ": 2.554901501703663, "Panic attack ": 4.36698777095376, "Panic disorder ": 3.300305981206497, "Panic reaction ": 2.249350837383586, "Paraesthesia ": 2.7454436504055706, "Paranoia ": 3.960282633794132, "Peripheral sensorimotor neuropathy ": 2.7841462594215542, "Persistent depressive disorder ": 3.636535455816395, "Personality change ": 2.131327960116097, "Phantom limb syndrome ": 7.860610807629707, "Physical assault ": 4.566041079955316, "Pituitary tumour benign ": 3.3243704632739943, "Placenta praevia ": 4.30131504773034, "Post-traumatic stress disorder ": 2.88483184122589, "Postoperative wound infection ": 2.927893806217169, "Potentiating drug interaction ": 3.570557902202204, "Prescribed overdose ": 2.884757437136783, "Psychogenic seizure ": 4.744806210036919, "Psychomotor hyperactivity ": 2.233385698802848, "Psychotic behaviour ": 2.699021846482917, "Pulmonary valve disease ": 28.8072066431291, "Reflexes abnormal ": 3.082568224084912, "Respiratory disorder neonatal ": 4.110690737252869, "Restless legs syndrome ": 3.075314982114855, "Restlessness ": 2.3646762507507044, "Rotator cuff syndrome ": 7.0658430004860495, "Salpingo-oophorectomy bilateral ": 56.50052127117235, "Scoliosis ": 10.161214654811335, "Seizure ": 2.253498713015853, "Self-destructive behaviour ": 4.050658288133336, "Self-injurious ideation ": 4.199279031616839, "Sensory disturbance ": 23.245802368493333, "Serotonin syndrome ": 18.65622994284165, "Sexual dysfunction ": 2.575726776579052, "Skin abrasion ": 2.192138576713639, "Skin laceration ": 3.4797844061269347, "Sleep deficit ": 2.844849661934622, "Sleep disorder ": 6.18770538779633, "Sleep talking ": 6.699704772098174, "Slow response to stimuli ": 2.006422507084177, "Snoring ": 3.43730149302737, "Social anxiety disorder ": 3.031544647647328, "Social avoidant behaviour ": 2.907042681504529, "Somatic symptom disorder ": 3.0790059857478966, "Somnambulism ": 2.928567944773277, "Sopor ": 2.0453293868930724, "Spinal fusion surgery ": 3.654433603404952, "Staring ": 2.357840608975428, "Suicidal behaviour ": 7.516592005680359, "Suicidal ideation ": 18.566736610768658, "Suicide attempt ": 7.225240397195066, "Systolic hypertension ": 3.3053713182837003, "Tachyphrenia ": 8.360011212844997, "Tardive dyskinesia ": 2.168629695426599, "Tendonitis ": 2.7339527060204096, "Thinking abnormal ": 3.738123581127328, "Tinnitus ": 4.130101106715045, "Tongue biting ": 2.072344799307741, "Transposition of the great vessels ": 3.658687899244266, "Tremor ": 3.55451544536296, "Ulnar nerve injury ": 10.630785699264049, "Urinary hesitation ": 5.018323696603995, "Urinary retention ": 2.358118189033612, "Urinary tract infection bacterial ": 5.474852993934862, "Uterine disorder ": 5.139953658140763, "Ventricular hypoplasia ": 12.47745812141054, "Vertigo ": 8.233718075081516, "Violence-related symptom ": 2.8368665638548527, "Viraemia ": 4.337558439054439, "Vitamin D decreased ": 2.991942822434851, "Weight increased ": 2.9705141682593785, "Withdrawal syndrome ": 9.560767610940456, "Wrong patient received product ": 2.037818023336037, "Yawning ": 4.72685073686399}
\ No newline at end of file
+{"Acute generalised exanthematous pustulosis": 5.903141674212228, "Acute kidney injury": 4.063178829203609, "Acute respiratory distress syndrome": 8.728420295067407, "Acute respiratory failure": 2.9269676779482365, "Alanine aminotransferase increased": 2.137439192012651, "Antimicrobial susceptibility test resistant": 2551.583420968558, "Anuria": 5.222896514313198, "Aspartate aminotransferase increased": 3.308233065245218, "Bacteraemia": 12.68108146363558, "Bacterial infection": 2.224147029965766, "Blood alkaline phosphatase increased": 4.006933761777246, "Blood creatine phosphokinase increased": 54.64423165305575, "Blood creatinine increased": 3.57564811076335, "C-reactive protein increased": 2.999257276831506, "Candida infection": 4.7311635423765965, "Cardiac valve rupture": 458.9805810301239, "Cardiac valve vegetation": 323.29525612114486, "Cholestasis": 2.4078672848134346, "Clostridium difficile colitis": 7.431467874360369, "Clostridium difficile infection": 2.3772193634066983, "Computerised tomogram abnormal": 20.141778659943853, "Creatinine renal clearance decreased": 4.480271865471554, "Crepitations": 12.116951230433182, "Cutaneous vasculitis": 7.300895969521969, "Death": 2.2522732678909376, "Dermatitis exfoliative generalised": 4.468505202781701, "Device related infection": 13.796878362177525, "Disseminated intravascular coagulation": 5.031266931004899, "Drug eruption": 3.2501904107130817, "Drug ineffective for unapproved indication": 9.444749775205455, "Drug reaction with eosinophilia and systemic symptoms": 10.729340102504926, "Drug resistance": 11.405141995636962, "Electrocardiogram T wave amplitude decreased": 66.05628602373844, "Embolism": 7.065997068771261, "Endocarditis": 54.16991503955047, "Endocarditis staphylococcal": 303.4296897289892, "Enterococcal bacteraemia": 195.76423322614875, "Enterococcal infection": 45.219181603164905, "Eosinophil count increased": 23.656250907188188, "Eosinophil percentage increased": 47.62854443960199, "Eosinophilia": 32.32341475709163, "Eosinophilic pneumonia": 682.0369350743701, "Eosinophilic pneumonia acute": 641.1133176788422, "Extradural abscess": 43.56351430047237, "Glomerulonephritis acute": 80.43272265657906, "Haemodialysis": 10.059418181292155, "Henoch-Schonlein purpura": 10.959818262048946, "Hepatic cytolysis": 4.97017628584627, "Hyperbilirubinaemia": 2.780444514671022, "Hyperkalaemia": 3.0152197504653, "Hypersensitivity pneumonitis": 35.72259692881654, "Hyperthermia": 3.183789971470352, "Hypertransaminasaemia": 4.715645780029284, "Hypoxia": 6.578677513883645, "Hypoxic-ischaemic encephalopathy": 19.176477140611063, "Infection": 2.5585112358098008, "International normalised ratio increased": 2.549046171444755, "Interstitial lung disease": 5.298761139421984, "Intervertebral discitis": 21.184428349468572, "Leukopenia": 2.2179027639470643, "Liver function test increased": 3.858283927757722, "Lung consolidation": 25.89168983292649, "Lung disorder": 4.417513773850411, "Lung infiltration": 36.95154364665658, "Mechanical ventilation": 9.780774841754138, "Mediastinal abscess": 237.4138931489093, "Mental status changes": 3.617554071226496, "Minimum inhibitory concentration": 685.2128261388098, "Multiple organ dysfunction syndrome": 8.244554343151947, "Myoglobin blood increased": 14.917097126754866, "Myopathy": 14.004946015509192, "Myositis": 10.66438994533109, "Nephropathy toxic": 2.8606416350262838, "Organising pneumonia": 23.709829370286045, "Osteomyelitis": 21.84415709602437, "Overdose": 2.4475557792468874, "Pancytopenia": 3.6665253818099344, "Pathogen resistance": 54.65440177605538, "Platelet count decreased": 2.1564889009075965, "Pleural effusion": 2.291803649182451, "Pneumonitis": 6.1574672326928725, "Product use in unapproved indication": 3.893665558017846, "Prothrombin time prolonged": 3.18714423285526, "Pulmonary eosinophilia": 497.9393578332279, "Pulmonary toxicity": 6.436333795181152, "Purpura": 2.030812692706112, "Rales": 3.57432013906676, "Rash maculo-papular": 2.7879823127235825, "Renal failure": 2.4700042221524687, "Renal impairment": 4.283992782238094, "Renal tubular necrosis": 3.827711585342008, "Respiratory distress": 2.5035017591251463, "Respiratory failure": 4.523991781686901, "Rhabdomyolysis": 29.34515103572772, "Sepsis": 5.292201549648189, "Septic embolus": 36.14716161049614, "Septic shock": 6.954123828398459, "Staphylococcal bacteraemia": 139.58746271416047, "Staphylococcal infection": 18.17486335122408, "Staphylococcal sepsis": 8.457407179613572, "Staphylococcus test positive": 22.673527040134186, "Status epilepticus": 2.0710652700024363, "Stevens-Johnson syndrome": 5.294157804415451, "Systemic candida": 12.551754928045783, "Systemic inflammatory response syndrome": 8.867362060286055, "Tachypnoea": 3.200440446364244, "Thrombocytopenia": 2.119788011260619, "Toxic epidermal necrolysis": 4.194768165959792, "Toxic skin eruption": 8.553486020549041, "Treatment failure": 4.689950787381013, "Tubulointerstitial nephritis": 9.117199007140034, "Vancomycin infusion reaction": 21.82925127112264, "White blood cell count increased": 3.0042416157594496, "Wound infection staphylococcal": 30.984574869612715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/309.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/309.json
index 9598a7dd19d..72b26bb4193 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/309.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/309.json
@@ -1 +1 @@
-{"Decreased appetite ": 2.1413946943176327, "Febrile neutropenia ": 33.47390484485422, "Hypertension ": 2.5248762972605103, "Interstitial lung disease ": 23.18550861369721, "Malignant neoplasm progression ": 30.20567096301881, "Nephrotic syndrome ": 54.95641009513694, "Neutropenia ": 3.851629025383612, "Neutrophil count decreased ": 41.06082429510501, "Platelet count decreased ": 5.210490175613992, "Proteinuria ": 21.88696057678864}
\ No newline at end of file
+{"Off label use": 7.276751543074841, "Transaminases increased": 73.43152422726374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/31.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/31.json
index 2ab1d84f649..9eba834f67b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/31.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/31.json
@@ -1 +1 @@
-{"Acute kidney injury ": 4.95455483802973, "Acute respiratory distress syndrome ": 15.33633069742082, "Agranulocytosis ": 6.932698091959746, "B-cell lymphoma ": 71.8739148565652, "Blood creatinine increased ": 4.2624158150112335, "COVID-19 pneumonia ": 17.890807725906352, "Confusional state ": 2.001633942195321, "Cytomegalovirus infection ": 18.197586265690884, "Death ": 2.763138541139967, "Diabetes mellitus ": 2.8074198527320195, "Diarrhoea ": 2.29093532676425, "Drug interaction ": 5.437171778323573, "Foetal growth restriction ": 29.98462593332849, "General physical health deterioration ": 2.374009487131179, "Hallucination ": 2.718963281340096, "Hyperkalaemia ": 2.963279342738166, "Immunosuppressant drug level decreased ": 139.8358572904043, "Immunosuppressant drug level increased ": 203.18370510793835, "Kidney transplant rejection ": 45.82340584018013, "Leukopenia ": 5.17567030453581, "Multiple organ dysfunction syndrome ": 7.873443172391126, "Neutropenia ": 4.757569884751916, "Pancreatitis acute ": 8.633271691888433, "Pancytopenia ": 5.262442904968156, "Pyelonephritis ": 24.124508803547105, "Sepsis ": 2.5709070448682443, "Thrombocytopenia ": 2.723217135192942, "Transplant rejection ": 51.16259280811333}
\ No newline at end of file
+{"Activated partial thromboplastin time abnormal": 374.0363049032791, "Acute coronary syndrome": 13.70516906522115, "Acute kidney injury": 10.81439547236485, "Acute myocardial infarction": 2.359219546992561, "Agranulocytosis": 5.865438592296768, "Angina unstable": 15.479043771721944, "Aortic arteriosclerosis": 23.48232328187073, "Ascites": 2.187343758074655, "Atrial fibrillation": 3.2486419813966, "Benign prostatic hyperplasia": 13.094574738344413, "Blood bilirubin abnormal": 53.80976153772515, "Blood creatine phosphokinase increased": 3.274314357603005, "Blood glucose abnormal": 4.061746726844235, "Cardiac failure": 3.38064726074611, "Cerebral haemorrhage": 2.6190569321645776, "Cholestasis": 5.3979945773698885, "Dermatitis bullous": 6.512396466399284, "Dermatitis exfoliative generalised": 7.671345391503486, "Diarrhoea": 2.183441224464569, "Eosinophilia": 4.995770764503242, "Gamma-glutamyltransferase increased": 2.231576725178692, "Gout": 45.28957475717383, "Haematocrit abnormal": 84.83115858496569, "Haematocrit decreased": 3.659162960649169, "Haemoglobin abnormal": 17.507165854840945, "Haemoglobin urine present": 552.9062051057653, "Hepatic cyst": 24.882408166713347, "Hepatic cytolysis": 5.321272963453179, "Hepatic lesion": 16.328117200140913, "Hiatus hernia": 5.582588316755717, "Hyperkalaemia": 9.77624542560364, "Hypertriglyceridaemia": 9.957229614831288, "International normalised ratio abnormal": 47.285773500199184, "Lactic acidosis": 5.488137201970899, "Liver function test abnormal": 2.563142161949059, "Lordosis": 180.443009541514, "Lung opacity": 13.708019745625666, "Mean cell haemoglobin increased": 64.76094136251939, "Mean cell volume increased": 47.93895969587346, "Mesenteric vein thrombosis": 46.54547915172089, "Metastases to soft tissue": 223.15815680677508, "Nasal congestion": 6.065396477830619, "Oedema peripheral": 2.745532332161233, "Osteochondrosis": 71.49008165803845, "Osteolysis": 49.32639738163517, "Osteoma": 508.6663422108844, "Pancreatitis": 2.141513994037576, "Pancreatitis acute": 6.239271696451349, "Pancytopenia": 4.300274501970052, "Photosensitivity reaction": 3.581741773776534, "Platelet count abnormal": 17.24623624646984, "Polycystic liver disease": 1213.2257357097942, "Prostatic specific antigen abnormal": 133.22310372597795, "Prothrombin time abnormal": 249.91234548566305, "Pruritus": 3.275024940642621, "Rash": 2.019631085797025, "Rash macular": 2.6211783547124523, "Rash maculo-papular": 2.9871620941197548, "Red blood cell abnormality": 75.97041186478117, "Red blood cell count decreased": 3.825161184222963, "Red blood cells urine positive": 109.21631177962252, "Renal failure": 2.571972713708934, "Renal impairment": 2.3911841859346668, "Rhabdomyolysis": 5.020321492051533, "Scoliosis": 13.971331872928133, "Sensory disturbance": 2.840218629350158, "Shock haemorrhagic": 11.695711414508777, "Skin exfoliation": 3.1829093869231304, "Spinal osteoarthritis": 10.768225035299528, "Splenic cyst": 479.8730691576315, "Splenic lesion": 237.75034501872392, "Splenic necrosis": 942.6503084745764, "Stevens-Johnson syndrome": 2.025770986385282, "Sudden death": 4.7770095456983945, "Toxic epidermal necrolysis": 2.7390671207000667, "Toxic skin eruption": 3.765239756867538, "Transaminases increased": 3.5135612277285304, "Transient ischaemic attack": 2.1805591176586105, "Troponin increased": 11.779090954283472, "Tubulointerstitial nephritis": 7.12079174613846, "Underdose": 5.749656061056414, "Urinary sediment present": 206.8367007482617, "White blood cells urine positive": 59.32756749472371, "Wrong technique in product usage process": 5.085637849223192}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/310.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/310.json
index 9b1d5b4b1cf..e5401eba6cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/310.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/310.json
@@ -1 +1 @@
-{"Abdominal compartment syndrome ": 15.57604961825209, "Abdominal infection ": 10.285658777435517, "Abdominal mass ": 6.648450219714082, "Abdominal tenderness ": 3.6750197177021184, "Activated partial thromboplastin time prolonged ": 3.438429960056684, "Acute cholecystitis necrotic ": 22.86089195551355, "Acute graft versus host disease ": 3.587126836832636, "Acute graft versus host disease in intestine ": 5.789035605391401, "Acute graft versus host disease in liver ": 11.880416269822566, "Acute graft versus host disease in skin ": 7.730972200496694, "Acute leukaemia ": 7.054406070085901, "Acute lymphocytic leukaemia ": 23.18504132189374, "Acute lymphocytic leukaemia recurrent ": 54.58684806722853, "Acute lymphocytic leukaemia refractory ": 133.8200401887634, "Acute myeloid leukaemia ": 18.521110045737835, "Acute myeloid leukaemia recurrent ": 154.0440395667228, "Acute promyelocytic leukaemia ": 13.900643101419472, "Acute respiratory distress syndrome ": 3.0476904407998053, "Acute respiratory failure ": 2.396873713587975, "Adenovirus infection ": 11.417995204227672, "Agranulocytosis ": 2.4646868362278846, "Alanine aminotransferase increased ": 2.4100306900599446, "Allogenic stem cell transplantation ": 25.408759514637143, "Alpha haemolytic streptococcal infection ": 47.05986632481543, "Aplastic anaemia ": 2.7634868926917022, "Appendicitis ": 3.660852485868422, "Ascites ": 2.2716440856686604, "Aspergillus infection ": 15.935425382432026, "Atelectasis ": 5.2362575992736815, "Atypical pneumonia ": 3.7276568503251672, "Axonal neuropathy ": 14.49784258602676, "B precursor type acute leukaemia ": 57.5122810435514, "B-cell lymphoma ": 3.7692094783503536, "B-cell lymphoma recurrent ": 56.52921272730367, "B-cell lymphoma refractory ": 112.08803591853076, "BK virus infection ": 8.457186047866314, "Bacteraemia ": 13.95244220028158, "Bacterial infection ": 11.848162457428147, "Bacterial sepsis ": 14.25766666869462, "Bipolar I disorder ": 9.40081124182709, "Blast cells present ": 29.330349030159496, "Blast crisis in myelogenous leukaemia ": 11.018826704935348, "Blood HIV RNA increased ": 17.218419021522823, "Blood bilirubin increased ": 3.3476088037624203, "Blood bilirubin unconjugated increased ": 12.071573834927326, "Blood culture positive ": 20.62004837738728, "Blood disorder ": 6.377455557356458, "Blood fibrinogen decreased ": 13.54617772855821, "Blood immunoglobulin A decreased ": 22.53023608901824, "Blood immunoglobulin G decreased ": 6.98489893239978, "Blood lactate dehydrogenase increased ": 8.172529681973671, "Blood lactic acid increased ": 3.445692605092733, "Bone marrow disorder ": 4.96426837717329, "Bone marrow failure ": 16.592443737939597, "Brain abscess ": 6.997565443782843, "Bronchopulmonary aspergillosis ": 15.747438688597022, "Burkitt's lymphoma ": 30.92677999308082, "Caesarean section ": 2.094640100912001, "Candida infection ": 6.608983697144195, "Candida sepsis ": 27.2784983733701, "Cardiac dysfunction ": 3.820968920288356, "Cardiac tamponade ": 3.167779705095913, "Cardiomyopathy ": 4.113149728952029, "Cardiotoxicity ": 8.865183445218223, "Catheter site erythema ": 6.249086575690802, "Catheter site pain ": 7.261041774239043, "Central nervous system infection ": 17.78686887311397, "Central nervous system lesion ": 2.580033639044916, "Central nervous system leukaemia ": 35.37615033599663, "Central nervous system lymphoma ": 80.22808013371929, "Central sleep apnoea syndrome ": 22.8904238492737, "Cerebral venous thrombosis ": 3.742591659437725, "Chest injury ": 6.263185677137105, "Chest wall mass ": 45.65588686346895, "Chloroma ": 35.535503929416336, "Cholecystitis ": 2.444960130502968, "Cholecystitis acute ": 3.176263728869182, "Chronic graft versus host disease ": 4.380936863763312, "Chronic lymphocytic leukaemia ": 3.991357663434518, "Chronic myeloid leukaemia ": 3.415735213168298, "Chronic sinusitis ": 3.443327558982505, "Clostridium difficile colitis ": 7.351137413831356, "Clostridium difficile infection ": 5.763065910988553, "Clostridium test positive ": 6.583859114937175, "Coagulopathy ": 3.193760208366643, "Colitis ": 4.273945618878503, "Complication associated with device ": 2.380440390420163, "Computerised tomogram abnormal ": 8.585450407730658, "Congenital aplasia ": 15.793214999759323, "Cystitis haemorrhagic ": 8.201168753931636, "Cytogenetic abnormality ": 16.441332592410845, "Cytogenetic analysis abnormal ": 7.301649011767729, "Cytokine release syndrome ": 4.605035216977831, "Cytomegalovirus chorioretinitis ": 19.10429481247694, "Cytomegalovirus infection ": 4.791314898670538, "Cytomegalovirus infection reactivation ": 9.58301553449448, "Cytomegalovirus viraemia ": 4.87524639858387, "Cytopenia ": 16.663481171374332, "Delivery ": 35.55598148693523, "Device related infection ": 3.0422651673140653, "Differentiation syndrome ": 38.50325125929505, "Diffuse large B-cell lymphoma ": 33.22414470690555, "Diffuse large B-cell lymphoma recurrent ": 109.84257728385565, "Diffuse large B-cell lymphoma refractory ": 114.89787607503868, "Disease complication ": 6.312276635523843, "Disease progression ": 12.715959300338916, "Disease recurrence ": 5.520821180831333, "Disseminated intravascular coagulation ": 3.660186505386039, "Drug resistance ": 3.6682188262294138, "Drug-induced liver injury ": 2.026401104778914, "Duodenal obstruction ": 35.94525437583702, "Encephalitis ": 4.314287024392828, "Encephalopathy ": 3.1851358349031726, "Engraftment syndrome ": 16.921972193368926, "Enteritis ": 4.548323001829614, "Enterobacter infection ": 61.83884298708227, "Enterococcal infection ": 8.532661766741862, "Enterococcus test positive ": 50.97053886214012, "Enterocolitis infectious ": 46.37593003976208, "Enterovirus infection ": 116.68565047832332, "Epstein-Barr virus infection ": 3.4555301212070413, "Escherichia bacteraemia ": 25.142345185944997, "Escherichia infection ": 14.761084256156671, "Escherichia sepsis ": 13.254884277002946, "Febrile bone marrow aplasia ": 16.05022267978736, "Febrile neutropenia ": 45.81071324906084, "Foetal anaemia ": 107.95678939511905, "Foetal growth restriction ": 2.3008489458749604, "Follicular lymphoma ": 29.339581089205733, "Full blood count decreased ": 2.756190249461182, "Fungaemia ": 32.423125896178675, "Fungal infection ": 6.771285987602036, "Fusarium infection ": 28.046526531043806, "Gallbladder enlargement ": 11.8698628159706, "Gastroenteritis norovirus ": 13.611437944761864, "Gastrointestinal inflammation ": 8.352669647091659, "Gastrointestinal toxicity ": 3.6019455128828524, "Gastrointestinal wall thickening ": 10.942681602711453, "Gene mutation ": 7.588635848261394, "Geotrichum infection ": 181.16345793633465, "Graft versus host disease ": 5.862931451392072, "Graft versus host disease in gastrointestinal tract ": 14.277123102281712, "Graft versus host disease in skin ": 9.656865195379297, "Granulocyte count decreased ": 8.331078621858817, "Granulocytopenia ": 7.421318138289921, "Haematotoxicity ": 8.532628794068346, "Haemodynamic instability ": 2.787054549417832, "Haemoglobin abnormal ": 21.192435046281325, "Haemoglobin decreased ": 3.648627479500718, "Haemophagocytic lymphohistiocytosis ": 9.633523333615232, "Hepatic lesion ": 3.3495688838688578, "Hepatic steatosis ": 2.2874937092487726, "Hepatitis B ": 5.271113976880163, "Hepatitis B reactivation ": 6.873191511730263, "Hepatomegaly ": 4.042389901088626, "Hepatosplenomegaly ": 4.6136682945475656, "Herpes simplex ": 5.380678817899063, "Hodgkin's disease ": 8.940471354094425, "Human bocavirus infection ": 63.03107189827492, "Human herpesvirus 6 infection ": 37.11896797527905, "Human herpesvirus 6 infection reactivation ": 26.09731633108, "Human herpesvirus 8 infection ": 32.49040592248048, "Hydronephrosis ": 2.346505604908505, "Hyperbilirubinaemia ": 8.00340091620727, "Hyperlipidaemia ": 2.0138679805726807, "Hypertransaminasaemia ": 3.7709309891317626, "Hypertriglyceridaemia ": 2.975052763041889, "Hypervolaemia ": 3.5097280343200747, "Hypoalbuminaemia ": 5.501123724480826, "Hypogammaglobulinaemia ": 29.900991162195343, "Hypogonadism ": 7.301649011767729, "Hypophagia ": 2.546276862235616, "Hypoxia ": 3.356690480536494, "Ileus ": 2.274358284995789, "Immune effector cell-associated neurotoxicity syndrome ": 5.067830109690039, "Immunodeficiency ": 2.117381157705677, "Immunosuppression ": 3.823556269592133, "Inappropriate antidiuretic hormone secretion ": 2.17238025138904, "Infection ": 4.226800370417621, "Infection in an immunocompromised host ": 57.770230171665865, "Inflammatory marker increased ": 4.390950891122365, "Intestinal perforation ": 3.5843806823334226, "Intra-abdominal haemorrhage ": 3.026902710183785, "Keratitis ": 4.042691824278513, "Klebsiella infection ": 13.35309864921058, "Klebsiella sepsis ": 22.266361062781044, "Laryngospasm ": 2.435335974190288, "Leukaemia ": 3.5443285638424578, "Leukaemia recurrent ": 28.267523141071106, "Leukocytosis ": 2.2877321042925938, "Leukoencephalopathy ": 15.70552442011438, "Leukopenia ": 2.5239899560495758, "Liver abscess ": 5.575072098749756, "Low birth weight baby ": 2.1407826356628017, "Lung consolidation ": 8.2002024625787, "Lung infiltration ": 2.60844876134563, "Lung opacity ": 6.036730017482625, "Lymphadenopathy mediastinal ": 4.695930233122192, "Lymphocyte count decreased ": 4.575501663910246, "Lymphocyte count increased ": 4.368453748466752, "Lymphoma ": 5.557509956389152, "Lymphopenia ": 2.077239725416044, "Malignant neoplasm progression ": 2.149678733019357, "Mantle cell lymphoma ": 31.931146453856304, "Mantle cell lymphoma recurrent ": 86.48253246507716, "Metastases to spleen ": 17.512252148486507, "Metastasis ": 2.3328121215426005, "Methaemoglobinaemia ": 14.07186529698887, "Minimal residual disease ": 33.544187395813935, "Mucormycosis ": 34.97631926772645, "Mucosal inflammation ": 15.740472236651442, "Multiple organ dysfunction syndrome ": 6.739153860369067, "Myelodysplastic syndrome ": 16.599059698990477, "Myelopathy ": 15.337413912491414, "Myelosuppression ": 20.35230207004287, "Necrosis ": 2.7619128609137733, "Neoplasm ": 2.602491106837406, "Neoplasm progression ": 2.495175503653735, "Neoplasm recurrence ": 18.0973582551348, "Nervous system disorder ": 2.6596998601594053, "Neurological decompensation ": 6.556559817281046, "Neuropathy peripheral ": 2.2718883026276244, "Neurotoxicity ": 5.400012623858544, "Neutropenia ": 5.314259646054684, "Neutropenic colitis ": 30.74581354202947, "Neutropenic infection ": 68.21820345943779, "Neutropenic sepsis ": 21.44495738479297, "Neutrophil count decreased ": 6.158538051637303, "Neutrophil count increased ": 2.6854346104900038, "Nodule ": 2.241301870784812, "Non-Hodgkin's lymphoma ": 7.635581201386291, "Non-Hodgkin's lymphoma recurrent ": 21.526101970521967, "Non-cardiac chest pain ": 10.769057248873136, "Norovirus test positive ": 23.799004635289663, "Obstructive sleep apnoea syndrome ": 2.724315726997285, "Off label use ": 3.0805570161282603, "Oral disorder ": 3.194451962349238, "Oral herpes ": 2.2722103677390884, "Organising pneumonia ": 2.5397925576383256, "Otitis media ": 2.909983131892154, "Pancytopenia ": 9.118206841572222, "Parainfluenzae virus infection ": 73.19461253797118, "Paraplegia ": 3.64482324948938, "Paronychia ": 4.426790638793492, "Pathogen resistance ": 4.700790345025746, "Pericoronitis ": 200.66396200307184, "Peripheral sensory neuropathy ": 6.633860156241059, "Platelet count abnormal ": 3.861330290451181, "Platelet count decreased ": 4.13457885030131, "Platelet count increased ": 2.2922483742357858, "Pleural effusion ": 3.425071193535427, "Pneumatosis intestinalis ": 16.22595817284289, "Pneumocystis jirovecii infection ": 14.945647142137853, "Pneumocystis jirovecii pneumonia ": 4.394982201765128, "Pneumonia cytomegaloviral ": 11.1639430085824, "Pneumonia fungal ": 24.842092675096893, "Pneumonia klebsiella ": 9.477767992865791, "Pneumonia necrotising ": 20.861977227008, "Pneumonia viral ": 4.427158217358356, "Post transplant lymphoproliferative disorder ": 3.5347068757922746, "Posterior reversible encephalopathy syndrome ": 12.250743157607856, "Premature delivery ": 12.853060264706691, "Procalcitonin increased ": 7.938607581413303, "Proctalgia ": 4.743904605819446, "Product use in unapproved indication ": 3.349528077700504, "Progressive multifocal leukoencephalopathy ": 5.10487787093283, "Pseudomonal sepsis ": 17.012471858250922, "Pseudomonas infection ": 12.371061814410146, "Pulmonary alveolar haemorrhage ": 2.0754669119067217, "Pulmonary haemorrhage ": 5.385205252880625, "Pulmonary mass ": 3.13730654094062, "Pulse absent ": 3.5795845893407408, "Pyomyositis ": 44.54872015749093, "Quadriparesis ": 4.3491671698186, "Recurrent cancer ": 4.344231902568605, "Refractory cancer ": 133.0906916254109, "Respiratory failure ": 3.310603810587456, "Respiratory syncytial virus infection ": 2.9732110193388244, "Rhinovirus infection ": 49.558251283999525, "Richter's syndrome ": 14.632347746663056, "Scedosporium infection ": 17.332703644595487, "Second primary malignancy ": 11.658445398650723, "Secondary immunodeficiency ": 29.495923097894487, "Sepsis ": 6.953581040441766, "Septic shock ": 12.912999659606957, "Serum ferritin increased ": 3.108025899253904, "Shock ": 2.0512098708896658, "Sialoadenitis ": 9.264159808038096, "Sinus tachycardia ": 4.523188940875042, "Sinusitis fungal ": 21.267871927788896, "Skin abrasion ": 3.16818893193674, "Skin infection ": 2.941933707968871, "Skin lesion ": 2.172306088148208, "Skin mass ": 3.671883340394436, "Skin toxicity ": 4.136057648139247, "Small for dates baby ": 3.360853853354893, "Small intestinal obstruction ": 3.0910296837717315, "Splenomegaly ": 3.441761004046104, "Staphylococcal bacteraemia ": 12.256940557521672, "Staphylococcal infection ": 4.552520600362821, "Staphylococcal sepsis ": 9.32876394480068, "Staphylococcus test positive ": 6.9257335106474125, "Stenotrophomonas infection ": 33.09178063487313, "Stillbirth ": 2.4237329318908407, "Stomatitis ": 2.975252445554612, "Streptococcal bacteraemia ": 34.90311658194775, "Streptococcal sepsis ": 24.48153756135591, "Subdural haemorrhage ": 2.442995380310994, "Systemic candida ": 16.958757636291455, "Systemic inflammatory response syndrome ": 3.004391599369833, "Systemic mycosis ": 11.018346918548264, "T-cell type acute leukaemia ": 53.02214639499286, "Therapeutic response decreased ": 2.071291989921132, "Therapy non-responder ": 4.496792943266767, "Therapy partial responder ": 7.576436500916198, "Thrombocytopenia ": 3.9602233097795576, "Tooth infection ": 4.400446714301371, "Total lung capacity decreased ": 7.008477902584493, "Trichosporon infection ": 48.17872143441225, "Tumour lysis syndrome ": 14.06014717213332, "Upper respiratory tract infection ": 2.310943791498685, "Vancomycin infusion reaction ": 5.785532944490518, "Varicella zoster virus infection ": 6.7404349733585445, "Vascular access complication ": 39.89214261637929, "Venoocclusive disease ": 12.064854536810708, "Venoocclusive liver disease ": 19.927056216908294, "Venous thrombosis ": 5.628463872028836, "Viraemia ": 18.039951093088472, "Viral infection ": 2.0753429258254905, "White blood cell count abnormal ": 6.951199444951618, "White blood cell count decreased ": 3.771167868541916, "White matter lesion ": 46.76206415659838}
\ No newline at end of file
+{"Completed suicide": 246.32742747638773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/311.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/311.json
index 4ee07a48045..7529fbe597b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/311.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/311.json
@@ -1 +1 @@
-{"Acute kidney injury ": 3.2959360786638765, "Atrial fibrillation ": 4.931400790226213, "Bradycardia ": 7.710796698915945, "Cerebrovascular accident ": 3.64274916671208, "Drug interaction ": 11.200062245279208, "Erythema multiforme ": 27.12061159193146, "Gastrointestinal haemorrhage ": 21.000419612953703, "Hypotension ": 3.36307978422681, "Rectal haemorrhage ": 11.599419205452095, "Treatment failure ": 6.931379670745067}
\ No newline at end of file
+{"Abnormal behaviour": 2.5785133784533807, "Abortion spontaneous": 2.48977824130413, "Abulia": 6.353422325430627, "Accidental death": 3.2454830037183373, "Activation syndrome": 8.635840045805667, "Affect lability": 98.92343627003233, "Affective disorder": 2.022134246591913, "Aggression": 3.4399732612646696, "Agitation": 15.24896970219831, "Agoraphobia": 4.040775733433027, "Akathisia": 3.070550751610774, "Alcohol abuse": 2.207284366606954, "Alcohol poisoning": 2.5053787351847827, "Alcoholism": 2.8586354447976894, "Amnesia": 2.027661610682178, "Anger": 8.667833588769883, "Angle closure glaucoma": 5.192083881069792, "Anorgasmia": 4.2948299796423575, "Anovulatory cycle": 4.8857613628162415, "Anticoagulation drug level above therapeutic": 2.1280490366634504, "Anxiety": 5.075658157969808, "Anxiety disorder": 3.199711244801668, "Apathy": 2.162967827304096, "Arachnoid cyst": 5.193136571394251, "Atrophy": 2.920468294537703, "Auditory disorder": 2.392620617653582, "Autoinflammatory disease": 10.511355711435918, "Bipolar I disorder": 3.9152794611957136, "Bipolar disorder": 4.07672783548286, "Blood pressure diastolic abnormal": 4.172901740285552, "Blood pressure diastolic decreased": 2.455534974710062, "Blood pressure fluctuation": 2.1483723183415058, "Blood pressure increased": 2.0007899475154205, "Blood pressure systolic increased": 4.3114041180803095, "Blood sodium decreased": 2.3624390132621955, "Blood viscosity increased": 11.11034861583951, "Body height decreased": 2.384160705732808, "Brain herniation": 2.6539025647792114, "Bruxism": 6.94688597340909, "Bursitis": 2.3551921786126364, "Central pain syndrome": 16.474063139931268, "Cephalo-pelvic disproportion": 15.579738767812554, "Cholecystectomy": 2.531339102615872, "Claustrophobia": 5.069620139108316, "Clonus": 2.4754834393416525, "Colitis microscopic": 3.815048637107656, "Completed suicide": 2.1041090162541183, "Complex regional pain syndrome": 2.194015371822212, "Concussion": 3.0039244848797506, "Confusional state": 4.839759332005514, "Conversion disorder": 3.050745048753865, "Coordination abnormal": 2.0034336489402227, "Costochondritis": 2.7723042347795066, "Crying": 4.000194320065611, "Cubital tunnel syndrome": 18.454830062797036, "Decompression sickness": 177.51117891722757, "Decreased interest": 2.879914488741464, "Decreased vibratory sense": 4.580825816906108, "Delusion": 2.0826207847324567, "Depressed mood": 2.346906499972235, "Depression": 3.011008503084016, "Depression suicidal": 2.578069007997776, "Depressive symptom": 2.2086400563131305, "Dermatomyositis": 2.7291637287675385, "Disinhibition": 2.0493884580962853, "Dissociation": 2.560283196404664, "Disturbance in attention": 2.70044452587039, "Dizziness": 2.259789861153083, "Drug interaction": 2.024670699053984, "Drug screen positive": 2.3209729195780286, "Drug withdrawal headache": 12.384351457445456, "Drug withdrawal syndrome": 54.62378811252613, "Dyskinesia": 2.348108055285279, "Dysphemia": 2.878691317063636, "Dysphoria": 127.09686259495606, "Ectopic pregnancy": 5.415066480153956, "Ejaculation disorder": 2.346156567612913, "Electric shock": 6.524999272462533, "Electric shock sensation": 77.96541811212425, "Emotional disorder": 2.6060879139155806, "Emotional poverty": 5.28269646569605, "Essential tremor": 8.911536473271578, "Eustachian tube dysfunction": 4.301143729361999, "Excessive eye blinking": 2.7489211056791096, "Exfoliative rash": 3.069331270634832, "Facial spasm": 5.818827609831024, "Fall": 2.1742514234834323, "Fear": 2.4943733240005512, "Fear of injection": 3.2750711160561, "Feeling abnormal": 2.692987670647684, "Feeling jittery": 2.2661541443277966, "Feeling of despair": 4.166641984353347, "Fibroadenoma of breast": 5.000017891119244, "Fibromyalgia": 3.3446197227359904, "Fine motor skill dysfunction": 3.0598883675315918, "Flat affect": 3.2245468868452765, "Food craving": 2.7602463590042765, "Gastric bypass": 16.5374669705985, "Gastrointestinal tube insertion": 11.168444030045542, "Gastrostomy": 4.543903209582577, "Generalised anxiety disorder": 2.8122520296477576, "Glaucoma": 2.682118682371012, "Glucose urine present": 5.747781102950112, "Gluten sensitivity": 9.199687047576406, "Growth hormone deficiency": 9.343179309338437, "Haemoglobin increased": 13.605723454803243, "Hallucination": 2.638512867638229, "Hallucination, auditory": 2.537536189929358, "Hallucination, visual": 2.005647947348569, "Hangover": 4.058855273990603, "Hepatic cirrhosis": 2.143769611106274, "Hepatic steatosis": 2.6678070703632946, "High density lipoprotein increased": 4.294621411714628, "Homicidal ideation": 6.8065288787294165, "Homicide": 2.244146296561926, "Hostility": 5.573615688860079, "Hyperhidrosis": 4.672849249931983, "Hypermobility syndrome": 4.413218134794631, "Hyperphagia": 2.8953914979000244, "Hyperreflexia": 2.518630076073634, "Hypertensive crisis": 2.5303845022633578, "Hypertonic bladder": 4.834773217360102, "Hypervigilance": 4.924578946749222, "Hypokinesia": 4.018658724545637, "Hypomania": 58.89903311115423, "Hyponatraemia": 4.128110352496909, "Hysterectomy": 4.822862929638955, "Impatience": 2.932554856385156, "Implant site extravasation": 5.43197385065716, "Implant site swelling": 11.140134853862186, "Impulsive behaviour": 2.909326704895814, "Inappropriate antidiuretic hormone secretion": 7.860593643921877, "Incoherent": 2.4082160856861456, "Increased upper airway secretion": 2.097195863062332, "Ingrowing nail": 4.58275815057203, "Insomnia": 6.038669298254446, "Intentional overdose": 2.6319792177212307, "Intentional product misuse": 2.6432747585056453, "Intentional self-injury": 2.070029299914488, "Investigation abnormal": 6.315326898444037, "Irritability": 19.784871304038678, "Ischaemic cerebral infarction": 2.6220188957517583, "Joint noise": 21.73929111585515, "Kidney congestion": 27.79040359143432, "Laziness": 3.049062261004409, "Lethargy": 6.884821138976774, "Libido decreased": 3.365138321046759, "Major depression": 3.3688885479285724, "Mania": 5.413414935247688, "Medical device site erosion": 18.671848464295277, "Memory impairment": 2.846830971216596, "Mental disorder": 2.2416703338062374, "Migraine without aura": 3.623405222915592, "Mixed anxiety and depressive disorder": 2.346200108292282, "Moaning": 2.686104286919186, "Mood swings": 23.309937717599205, "Morbid thoughts": 2.774525712990896, "Motion sickness": 2.0719476996798294, "Muscle atrophy": 4.958493366109337, "Muscle spasticity": 3.453955598142701, "Muscle tightness": 3.0678312101590786, "Muscle twitching": 2.0885743585992183, "Musculoskeletal pain": 2.1399937820730126, "Mydriasis": 6.21292241917744, "Myoclonus": 2.079799582006377, "Neck injury": 2.0704844970693874, "Negative thoughts": 3.5125366127135917, "Nervousness": 2.145381890674427, "Nightmare": 16.03963370416974, "Obsessive thoughts": 5.033858318680031, "Ocular discomfort": 4.162140869780567, "Ocular vascular disorder": 3.611842414516485, "Oesophageal disorder": 2.346536871950712, "Oesophageal spasm": 2.847355689287922, "Open angle glaucoma": 4.378800262505348, "Ophthalmic vein thrombosis": 3.823907393678701, "Orgasm abnormal": 5.169757602813816, "Orthostatic hypotension": 2.7946640346117606, "Osteoarthritis": 2.5547997346865787, "Panic attack": 4.366813821248432, "Panic disorder": 3.300174529860593, "Panic reaction": 2.249261245525911, "Paraesthesia": 2.7468876197797543, "Paranoia": 3.9601248898739394, "Peripheral sensorimotor neuropathy": 2.7840353685044845, "Persistent depressive disorder": 3.63639061514326, "Personality change": 2.1312430686808117, "Phantom limb syndrome": 7.860297724552379, "Physical assault": 4.565859215679509, "Pituitary tumour benign": 3.324238055229316, "Placenta praevia": 4.301143729361999, "Post-traumatic stress disorder": 2.884716938286347, "Postoperative wound infection": 2.927777188698605, "Potentiating drug interaction": 3.570415685967619, "Prescribed overdose": 2.884642532235161, "Psychogenic seizure": 4.744617226483364, "Psychomotor hyperactivity": 2.232905787936908, "Psychotic behaviour": 2.6989143462109286, "Pulmonary valve disease": 28.80605927402258, "Reflexes abnormal": 3.0824454475329643, "Respiratory disorder neonatal": 4.110527010473364, "Restless legs syndrome": 3.075192488312809, "Restlessness": 2.364455528251644, "Rotator cuff syndrome": 7.065561557502653, "Salpingo-oophorectomy bilateral": 56.49827087661525, "Scoliosis": 10.160809921090328, "Seizure": 2.2531557041022885, "Self-destructive behaviour": 4.050496948765362, "Self-injurious ideation": 4.199111774155105, "Sensory disturbance": 23.24487633384121, "Serotonin syndrome": 18.65548674830415, "Sexual dysfunction": 2.575624184137526, "Skin abrasion": 2.192051263992367, "Skin laceration": 3.4796458034779367, "Sleep deficit": 2.844736352961452, "Sleep disorder": 6.187458888797177, "Sleep talking": 6.699437925479039, "Slow response to stimuli": 2.00634259212635, "Snoring": 3.437164585659436, "Social anxiety disorder": 3.0314239032146166, "Social avoidant behaviour": 2.9069268938474484, "Somatic symptom disorder": 3.078883349683028, "Somnambulism": 2.928451300136537, "Sopor": 2.045247920330149, "Spinal fusion surgery": 3.654288048489728, "Staring": 2.357746696925698, "Suicidal behaviour": 7.516292613349734, "Suicidal ideation": 18.56599684700601, "Suicide attempt": 7.224952559710467, "Systolic hypertension": 3.3052396672855413, "Tachyphrenia": 8.359678232335979, "Tardive dyskinesia": 2.1685433181393106, "Tendonitis": 2.7338438088382557, "Thinking abnormal": 3.737974687034054, "Tinnitus": 4.129936578264826, "Tongue biting": 2.0722622589501536, "Transposition of the great vessels": 3.6585421761180834, "Tremor": 3.5542366634402582, "Ulnar nerve injury": 10.630362283209006, "Urinary hesitation": 5.018123817001324, "Urinary retention": 2.358024258672537, "Urinary tract infection bacterial": 5.474634931287365, "Uterine disorder": 5.1397489357570825, "Ventricular hypoplasia": 12.47696115252158, "Vertigo": 8.233390041761487, "Violence-related symptom": 2.836753572933254, "Viraemia": 4.337385675288381, "Vitamin D decreased": 2.991823653517097, "Weight increased": 2.9703958341811783, "Withdrawal syndrome": 9.560386756140415, "Wrong patient received product": 2.037736857575716, "Yawning": 4.726662466709295}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/312.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/312.json
index 816253544e7..72973af4f6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/312.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/312.json
@@ -1 +1 @@
-{"Anaplastic thyroid cancer ": 1006.3657503455536, "BRAF V600E mutation positive ": 1004.5702561249988, "Blood creatine phosphokinase increased ": 5.361261175640397, "Blood lactate dehydrogenase increased ": 6.416465175399551, "Blood test abnormal ": 9.799284165527297, "C-reactive protein increased ": 2.9745741184208128, "Cognitive disorder ": 2.78332873890958, "Colitis ": 2.4084367606706825, "Dermatitis acneiform ": 14.005125160685402, "Disease progression ": 3.3771378019265934, "Disease recurrence ": 2.3186438956629987, "Drug reaction with eosinophilia and systemic symptoms ": 3.6043146061928, "Drug resistance ": 8.563251101083688, "Dysphagia ": 2.5750605699166345, "Ejection fraction decreased ": 28.59351053125258, "Erythema nodosum ": 15.347927069937317, "Fear ": 4.666537695235013, "Haemophagocytic lymphohistiocytosis ": 14.5978623926523, "Hepatitis ": 2.43402874286642, "Hepatotoxicity ": 2.916078764798514, "Hyperpyrexia ": 4.713689506436015, "Hyperthyroidism ": 2.1316720979895387, "Intentional product use issue ": 2.141262215847849, "Liver function test increased ": 2.319048612076317, "Lung adenocarcinoma ": 25.76589602633331, "Malignant melanoma ": 62.77887682052799, "Malignant melanoma stage IV ": 110.14107887544486, "Malignant neoplasm progression ": 33.366863067596874, "Melanoma recurrent ": 101.38713681701633, "Metastases to bone ": 10.48483944623639, "Metastases to central nervous system ": 74.25310461855811, "Metastases to liver ": 13.449048807140931, "Metastases to lung ": 26.540211495558733, "Metastases to lymph nodes ": 30.70553947850328, "Metastases to meninges ": 59.98765145654069, "Metastases to skin ": 77.26958700981854, "Metastasis ": 11.510920545905874, "Metastatic malignant melanoma ": 398.4923391902726, "Mucosal inflammation ": 6.212920658691106, "Neoplasm ": 9.161247639507623, "Neoplasm progression ": 2.573619239728883, "Neutropenia ": 3.1551653707704035, "Non-small cell lung cancer ": 13.876856684339211, "Oesophagitis ": 10.19261524565018, "Panniculitis ": 33.217689177885575, "Pemphigoid ": 4.396866657824431, "Peripheral motor neuropathy ": 45.268081504696575, "Peripheral sensory neuropathy ": 10.448255366274385, "Pneumonitis ": 8.993253828545377, "Polyneuropathy ": 4.975738969265043, "Product use in unapproved indication ": 5.758747823023028, "Pulmonary mass ": 6.528449299665128, "Pyrexia ": 2.48585847194192, "Rhabdomyolysis ": 2.4133314712281444, "Sarcoidosis ": 11.07554627931574, "Skin toxicity ": 23.845245938097648, "Therapeutic response decreased ": 6.037042566921579, "Therapy partial responder ": 40.26413926134357, "Uveitis ": 35.17084728831189}
\ No newline at end of file
+{"Decreased appetite": 2.141373924932156, "Febrile neutropenia": 33.47390484485422, "Hypertension": 2.52485023390373, "Interstitial lung disease": 23.18550861369721, "Malignant neoplasm progression": 30.20567096301881, "Nephrotic syndrome": 54.95641009513694, "Neutropenia": 3.851463410695405, "Neutrophil count decreased": 41.06082429510501, "Platelet count decreased": 5.210490175613992, "Proteinuria": 21.88696057678864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/313.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/313.json
index 66dfe300739..a94d87ea476 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/313.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/313.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 2.321318364335335, "Anaemia ": 3.8876991939893264, "Anuria ": 10.4227031742893, "Ascites ": 15.145343648683788, "Aspartate aminotransferase increased ": 3.347161770117708, "Blindness ": 2.910394317097917, "Blood bilirubin increased ": 4.212472746770841, "Blood pressure decreased ": 2.5939334539815757, "Bradycardia ": 3.49247399722273, "Cachexia ": 24.54439833452568, "Chronic hepatitis C ": 153.81904732081443, "Drug ineffective ": 12.037632053050023, "Drug interaction ": 3.134264434079593, "Drug resistance ": 3.4354189144129426, "Duodenitis ": 42.56792082718861, "Encephalopathy ": 9.29907867292176, "Foot fracture ": 6.381036602960899, "Gamma-glutamyltransferase increased ": 4.354495610237676, "Gastritis ": 5.466515698962911, "Genotype drug resistance test positive ": 605.38686445476, "HIV infection ": 94.41371560596392, "Hepatic cancer ": 7.679390704427341, "Hepatic cirrhosis ": 17.979465592968364, "Hepatic encephalopathy ": 21.348871507731868, "Hepatic failure ": 14.654868112645074, "Hepatitis C ": 192.08409143741375, "Hepatocellular carcinoma ": 58.54203475195683, "Hypophagia ": 6.911485154585296, "Iridocyclitis ": 28.21281420339721, "Liver transplant ": 131.16569623171617, "Oesophagitis ": 14.351529796099808, "Off label use ": 2.288228675666949, "Oral candidiasis ": 7.061174146273633, "Platelet count increased ": 10.086642594741278, "Proteinuria ": 3.5154205941141465, "Pulmonary arterial hypertension ": 14.949931443156368, "Refusal of treatment by patient ": 164.33060163135738, "Renal impairment ": 2.70500352558643, "Rhabdomyolysis ": 2.1838001674814382, "Therapy non-responder ": 4.348659203762147, "Treatment failure ": 75.98729350941606, "Treatment noncompliance ": 4.588858163537847, "Viral mutation identified ": 149.25009093444734, "Virologic failure ": 106.23972147270464}
\ No newline at end of file
+{"Abdominal compartment syndrome": 15.57604961825209, "Abdominal infection": 10.285658777435517, "Abdominal mass": 6.648450219714082, "Abdominal tenderness": 3.6750197177021184, "Activated partial thromboplastin time prolonged": 3.438429960056684, "Acute cholecystitis necrotic": 22.86089195551355, "Acute graft versus host disease": 3.587126836832636, "Acute graft versus host disease in intestine": 5.789035605391401, "Acute graft versus host disease in liver": 11.880416269822566, "Acute graft versus host disease in skin": 7.730972200496694, "Acute leukaemia": 7.054406070085901, "Acute lymphocytic leukaemia": 23.18504132189374, "Acute lymphocytic leukaemia recurrent": 54.58684806722853, "Acute lymphocytic leukaemia refractory": 133.8200401887634, "Acute myeloid leukaemia": 18.521110045737835, "Acute myeloid leukaemia recurrent": 154.0440395667228, "Acute promyelocytic leukaemia": 13.900643101419472, "Acute respiratory distress syndrome": 3.0476904407998053, "Acute respiratory failure": 2.396873713587975, "Adenovirus infection": 11.417995204227672, "Agranulocytosis": 2.4646868362278846, "Alanine aminotransferase increased": 2.4100306900599446, "Allogenic stem cell transplantation": 25.408759514637143, "Alpha haemolytic streptococcal infection": 47.05986632481543, "Aplastic anaemia": 2.7634868926917022, "Appendicitis": 3.660852485868422, "Ascites": 2.2716440856686604, "Aspergillus infection": 15.935425382432026, "Atelectasis": 5.2362575992736815, "Atypical pneumonia": 3.7276568503251672, "Axonal neuropathy": 14.49784258602676, "B precursor type acute leukaemia": 57.5122810435514, "B-cell lymphoma": 3.7692094783503536, "B-cell lymphoma recurrent": 56.52921272730367, "B-cell lymphoma refractory": 112.08803591853076, "BK virus infection": 8.457186047866314, "Bacteraemia": 13.95244220028158, "Bacterial infection": 11.848162457428147, "Bacterial sepsis": 14.25766666869462, "Bipolar I disorder": 9.40081124182709, "Blast cells present": 29.330349030159496, "Blast crisis in myelogenous leukaemia": 11.018826704935348, "Blood HIV RNA increased": 17.218419021522823, "Blood bilirubin increased": 3.3476088037624203, "Blood bilirubin unconjugated increased": 12.071573834927326, "Blood culture positive": 20.62004837738728, "Blood disorder": 6.377455557356458, "Blood fibrinogen decreased": 13.54617772855821, "Blood immunoglobulin A decreased": 22.53023608901824, "Blood immunoglobulin G decreased": 6.98489893239978, "Blood lactate dehydrogenase increased": 8.172529681973671, "Blood lactic acid increased": 3.445692605092733, "Bone marrow disorder": 4.96426837717329, "Bone marrow failure": 16.592443737939597, "Brain abscess": 6.997565443782843, "Bronchopulmonary aspergillosis": 15.747438688597022, "Burkitt's lymphoma": 30.92677999308082, "Caesarean section": 2.094640100912001, "Candida infection": 6.608983697144195, "Candida sepsis": 27.2784983733701, "Cardiac dysfunction": 3.820968920288356, "Cardiac tamponade": 3.167779705095913, "Cardiomyopathy": 4.113149728952029, "Cardiotoxicity": 8.865183445218223, "Catheter site erythema": 6.249086575690802, "Catheter site pain": 7.261041774239043, "Central nervous system infection": 17.78686887311397, "Central nervous system lesion": 2.580033639044916, "Central nervous system leukaemia": 35.37615033599663, "Central nervous system lymphoma": 80.22808013371929, "Central sleep apnoea syndrome": 22.8904238492737, "Cerebral venous thrombosis": 3.742591659437725, "Chest injury": 6.263185677137105, "Chest wall mass": 45.65588686346895, "Chloroma": 35.535503929416336, "Cholecystitis": 2.444960130502968, "Cholecystitis acute": 3.176263728869182, "Chronic graft versus host disease": 4.380936863763312, "Chronic lymphocytic leukaemia": 3.988002242689352, "Chronic myeloid leukaemia": 3.415735213168298, "Chronic sinusitis": 3.443327558982505, "Clostridium difficile colitis": 7.351137413831356, "Clostridium difficile infection": 5.763065910988553, "Clostridium test positive": 6.583859114937175, "Coagulopathy": 3.193760208366643, "Colitis": 4.273945618878503, "Complication associated with device": 2.380440390420163, "Computerised tomogram abnormal": 8.585450407730658, "Congenital aplasia": 15.742626402048776, "Cystitis haemorrhagic": 8.201168753931636, "Cytogenetic abnormality": 16.441332592410845, "Cytogenetic analysis abnormal": 7.301649011767729, "Cytokine release syndrome": 4.605035216977831, "Cytomegalovirus chorioretinitis": 19.10429481247694, "Cytomegalovirus infection": 4.791314898670538, "Cytomegalovirus infection reactivation": 9.58301553449448, "Cytomegalovirus viraemia": 4.87524639858387, "Cytopenia": 16.64986429444131, "Delivery": 35.55598148693523, "Device related infection": 3.0422651673140653, "Differentiation syndrome": 38.50325125929505, "Diffuse large B-cell lymphoma": 33.22414470690555, "Diffuse large B-cell lymphoma recurrent": 109.84257728385565, "Diffuse large B-cell lymphoma refractory": 114.89787607503868, "Disease complication": 6.312276635523843, "Disease progression": 12.715959300338916, "Disease recurrence": 5.520821180831333, "Disseminated intravascular coagulation": 3.660186505386039, "Drug resistance": 3.6682188262294138, "Drug-induced liver injury": 2.026277219033246, "Duodenal obstruction": 35.94525437583702, "Encephalitis": 4.314287024392828, "Encephalopathy": 3.1851358349031726, "Engraftment syndrome": 16.921972193368926, "Enteritis": 4.548323001829614, "Enterobacter infection": 61.83884298708227, "Enterococcal infection": 8.532661766741862, "Enterococcus test positive": 50.97053886214012, "Enterocolitis infectious": 46.37593003976208, "Enterovirus infection": 116.68565047832332, "Epstein-Barr virus infection": 3.4555301212070413, "Escherichia bacteraemia": 25.142345185944997, "Escherichia infection": 14.761084256156671, "Escherichia sepsis": 13.254884277002946, "Febrile bone marrow aplasia": 16.05022267978736, "Febrile neutropenia": 45.81071324906084, "Foetal anaemia": 107.95678939511905, "Foetal growth restriction": 2.3008489458749604, "Follicular lymphoma": 29.339581089205733, "Full blood count decreased": 2.756190249461182, "Fungaemia": 32.423125896178675, "Fungal infection": 6.76938673192877, "Fusarium infection": 28.046526531043806, "Gallbladder enlargement": 11.8698628159706, "Gastroenteritis norovirus": 13.611437944761864, "Gastrointestinal inflammation": 8.352669647091659, "Gastrointestinal toxicity": 3.6019455128828524, "Gastrointestinal wall thickening": 10.942681602711453, "Gene mutation": 7.588635848261394, "Geotrichum infection": 181.16345793633465, "Graft versus host disease": 5.862931451392072, "Graft versus host disease in gastrointestinal tract": 14.277123102281712, "Graft versus host disease in skin": 9.656865195379297, "Granulocyte count decreased": 8.331078621858817, "Granulocytopenia": 7.419154551259774, "Haematotoxicity": 8.532628794068346, "Haemodynamic instability": 2.787054549417832, "Haemoglobin abnormal": 21.192435046281325, "Haemoglobin decreased": 3.648627479500718, "Haemophagocytic lymphohistiocytosis": 9.633523333615232, "Hepatic lesion": 3.3495688838688578, "Hepatic steatosis": 2.2874937092487726, "Hepatitis B": 5.271113976880163, "Hepatitis B reactivation": 6.873191511730263, "Hepatomegaly": 4.042389901088626, "Hepatosplenomegaly": 4.6136682945475656, "Herpes simplex": 5.380678817899063, "Hodgkin's disease": 8.940471354094425, "Human bocavirus infection": 63.03107189827492, "Human herpesvirus 6 infection": 37.11896797527905, "Human herpesvirus 6 infection reactivation": 26.09731633108, "Human herpesvirus 8 infection": 32.49040592248048, "Hydronephrosis": 2.346505604908505, "Hyperbilirubinaemia": 8.00340091620727, "Hyperlipidaemia": 2.0138679805726807, "Hypertransaminasaemia": 3.7709309891317626, "Hypertriglyceridaemia": 2.975052763041889, "Hypervolaemia": 3.5097280343200747, "Hypoalbuminaemia": 5.501123724480826, "Hypogammaglobulinaemia": 29.900991162195343, "Hypogonadism": 7.301649011767729, "Hypophagia": 2.546276862235616, "Hypoxia": 3.356690480536494, "Ileus": 2.274358284995789, "Immune effector cell-associated neurotoxicity syndrome": 5.067830109690039, "Immunodeficiency": 2.117381157705677, "Immunosuppression": 3.823556269592133, "Inappropriate antidiuretic hormone secretion": 2.17238025138904, "Infection": 4.226800370417621, "Infection in an immunocompromised host": 57.770230171665865, "Inflammatory marker increased": 4.390950891122365, "Intestinal perforation": 3.5843806823334226, "Intra-abdominal haemorrhage": 3.026902710183785, "Keratitis": 4.042691824278513, "Klebsiella infection": 13.35309864921058, "Klebsiella sepsis": 22.266361062781044, "Laryngospasm": 2.435335974190288, "Leukaemia": 3.5443285638424578, "Leukaemia recurrent": 28.267523141071106, "Leukocytosis": 2.2877321042925938, "Leukoencephalopathy": 15.70552442011438, "Leukopenia": 2.5236705340132217, "Liver abscess": 5.575072098749756, "Low birth weight baby": 2.1407826356628017, "Lung consolidation": 8.2002024625787, "Lung infiltration": 2.60844876134563, "Lung opacity": 6.036730017482625, "Lymphadenopathy mediastinal": 4.695930233122192, "Lymphocyte count decreased": 4.575501663910246, "Lymphocyte count increased": 4.368453748466752, "Lymphoma": 5.557509956389152, "Lymphopenia": 2.077239725416044, "Malignant neoplasm progression": 2.149678733019357, "Mantle cell lymphoma": 31.931146453856304, "Mantle cell lymphoma recurrent": 86.48253246507716, "Metastases to spleen": 17.512252148486507, "Metastasis": 2.3328121215426005, "Methaemoglobinaemia": 14.07186529698887, "Minimal residual disease": 33.544187395813935, "Mucormycosis": 34.97631926772645, "Mucosal inflammation": 15.740472236651442, "Multiple organ dysfunction syndrome": 6.739153860369067, "Myelodysplastic syndrome": 16.599059698990477, "Myelopathy": 15.337413912491414, "Myelosuppression": 20.35230207004287, "Necrosis": 2.7619128609137733, "Neoplasm": 2.602491106837406, "Neoplasm progression": 2.495175503653735, "Neoplasm recurrence": 18.0973582551348, "Nervous system disorder": 2.6596998601594053, "Neurological decompensation": 6.556559817281046, "Neuropathy peripheral": 2.2718190854223166, "Neurotoxicity": 5.400012623858544, "Neutropenia": 5.31402916824118, "Neutropenic colitis": 30.74581354202947, "Neutropenic infection": 68.21820345943779, "Neutropenic sepsis": 21.44495738479297, "Neutrophil count decreased": 6.158538051637303, "Neutrophil count increased": 2.6854346104900038, "Nodule": 2.241301870784812, "Non-Hodgkin's lymphoma": 7.635581201386291, "Non-Hodgkin's lymphoma recurrent": 21.526101970521967, "Non-cardiac chest pain": 10.769057248873136, "Norovirus test positive": 23.799004635289663, "Obstructive sleep apnoea syndrome": 2.724315726997285, "Off label use": 3.080435085657683, "Oral disorder": 3.194451962349238, "Oral herpes": 2.2722103677390884, "Organising pneumonia": 2.5397925576383256, "Otitis media": 2.909983131892154, "Pancytopenia": 9.118206841572222, "Parainfluenzae virus infection": 73.19461253797118, "Paraplegia": 3.64482324948938, "Paronychia": 4.426790638793492, "Pathogen resistance": 4.700790345025746, "Pericoronitis": 200.66396200307184, "Peripheral sensory neuropathy": 6.633860156241059, "Platelet count abnormal": 3.861330290451181, "Platelet count decreased": 4.13457885030131, "Platelet count increased": 2.2922483742357858, "Pleural effusion": 3.4247541240016908, "Pneumatosis intestinalis": 16.22595817284289, "Pneumocystis jirovecii infection": 14.945647142137853, "Pneumocystis jirovecii pneumonia": 4.394982201765128, "Pneumonia cytomegaloviral": 11.1639430085824, "Pneumonia fungal": 24.842092675096893, "Pneumonia klebsiella": 9.477767992865791, "Pneumonia necrotising": 20.861977227008, "Pneumonia viral": 4.427158217358356, "Post transplant lymphoproliferative disorder": 3.5347068757922746, "Posterior reversible encephalopathy syndrome": 12.250743157607856, "Premature delivery": 12.853060264706691, "Procalcitonin increased": 7.938607581413303, "Proctalgia": 4.743904605819446, "Product use in unapproved indication": 3.3494230620746683, "Progressive multifocal leukoencephalopathy": 5.10487787093283, "Pseudomonal sepsis": 17.012471858250922, "Pseudomonas infection": 12.371061814410146, "Pulmonary alveolar haemorrhage": 2.0754669119067217, "Pulmonary haemorrhage": 5.385205252880625, "Pulmonary mass": 3.13730654094062, "Pulse absent": 3.5795845893407408, "Pyomyositis": 44.54872015749093, "Quadriparesis": 4.3491671698186, "Recurrent cancer": 4.344231902568605, "Refractory cancer": 133.0906916254109, "Respiratory failure": 3.310329025545068, "Respiratory syncytial virus infection": 2.9732110193388244, "Rhinovirus infection": 49.558251283999525, "Richter's syndrome": 14.632347746663056, "Scedosporium infection": 17.332703644595487, "Second primary malignancy": 11.658445398650723, "Secondary immunodeficiency": 29.495923097894487, "Sepsis": 6.953581040441766, "Septic shock": 12.912999659606957, "Serum ferritin increased": 3.108025899253904, "Shock": 2.0512098708896658, "Sialoadenitis": 9.264159808038096, "Sinus tachycardia": 4.523188940875042, "Sinusitis fungal": 21.267871927788896, "Skin abrasion": 3.16818893193674, "Skin infection": 2.941933707968871, "Skin lesion": 2.172306088148208, "Skin mass": 3.671883340394436, "Skin toxicity": 4.130102142079066, "Small for dates baby": 3.360853853354893, "Small intestinal obstruction": 3.0910296837717315, "Splenomegaly": 3.441761004046104, "Staphylococcal bacteraemia": 12.256940557521672, "Staphylococcal infection": 4.552520600362821, "Staphylococcal sepsis": 9.32876394480068, "Staphylococcus test positive": 6.9257335106474125, "Stenotrophomonas infection": 33.09178063487313, "Stillbirth": 2.4237329318908407, "Stomatitis": 2.975252445554612, "Streptococcal bacteraemia": 34.90311658194775, "Streptococcal sepsis": 24.48153756135591, "Subdural haemorrhage": 2.442995380310994, "Systemic candida": 16.958757636291455, "Systemic inflammatory response syndrome": 3.004391599369833, "Systemic mycosis": 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46.76206415659838}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/314.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/314.json
index 81311a698c1..c97b90f8c00 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/314.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/314.json
@@ -1 +1 @@
-{"Acne ": 136.8127877847876, "Alopecia ": 24.773519376552883, "Condition aggravated ": 13.027889767419628, "Drug ineffective ": 4.108829562545642, "Incorrect route of product administration ": 48.17924502154337, "Liver function test abnormal ": 88.08209458992357, "Loss of personal independence in daily activities ": 31.3291419328828, "Ovarian cyst ": 621.1673489199251, "Overdose ": 15.257887090500232, "Pain ": 4.513551486942567, "Pneumonia ": 12.520733498148957, "Product use issue ": 14.312856635970098, "Rheumatoid arthritis ": 23.24494276485305, "Sleep disorder due to general medical condition, insomnia type ": 415.4554398077158, "Transplant dysfunction ": 3246.845549148953, "Transplant rejection ": 606.33233441694}
\ No newline at end of file
+{"Acute kidney injury": 2.778175833994755, "Atrial fibrillation": 4.157033904037721, "Bradycardia": 6.499457051808103, "Cerebrovascular accident": 3.4017592568296644, "Deep vein thrombosis": 8.230426053691161, "Drug interaction": 9.436316181986056, "Erythema multiforme": 22.86023197250304, "Gastrointestinal haemorrhage": 17.695302213872797, "Hypotension": 2.8346402977214957, "Pulmonary embolism": 3.1584762651055343, "Rectal haemorrhage": 10.832610386304449, "Treatment failure": 5.843284401240023}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/315.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/315.json
index 87890030d35..b1a7a0df57f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/315.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/315.json
@@ -1 +1 @@
-{"Fall ": 4.527711334745462, "Febrile neutropenia ": 17.857217806011302, "Neutropenia ": 6.931874432108761, "Off label use ": 2.5350928264030665, "Pancytopenia ": 11.229998603806642, "Platelet count decreased ": 6.849634710478662, "Product use in unapproved indication ": 5.013356047325156, "Weight decreased ": 3.5838359404994424, "White blood cell count decreased ": 7.00772534734014}
\ No newline at end of file
+{"Anaplastic thyroid cancer": 1006.3657503455536, "BRAF V600E mutation positive": 1004.5702561249988, "Blood creatine phosphokinase increased": 5.361261175640397, "Blood lactate dehydrogenase increased": 6.416465175399551, "Blood test abnormal": 9.799284165527297, "C-reactive protein increased": 2.9745741184208128, "Cognitive disorder": 2.78332873890958, "Colitis": 2.4084367606706825, "Dermatitis acneiform": 14.005125160685402, "Disease progression": 3.3771378019265934, "Disease recurrence": 2.3186438956629987, "Drug reaction with eosinophilia and systemic symptoms": 3.60401680676962, "Drug resistance": 8.563251101083688, "Dysphagia": 2.5750605699166345, "Ejection fraction decreased": 28.59351053125258, "Erythema nodosum": 15.347927069937317, "Fear": 4.666537695235013, "Haemophagocytic lymphohistiocytosis": 14.5978623926523, "Hepatitis": 2.43402874286642, "Hepatotoxicity": 2.916078764798514, "Hyperpyrexia": 4.713689506436015, "Hyperthyroidism": 2.131478155385784, "Intentional product use issue": 2.141262215847849, "Liver function test increased": 2.319048612076317, "Lung adenocarcinoma": 25.76589602633331, "Malignant melanoma": 62.77887682052799, "Malignant melanoma stage IV": 110.14107887544486, "Malignant neoplasm progression": 33.366863067596874, "Melanoma recurrent": 101.38713681701633, "Metastases to bone": 10.48483944623639, "Metastases to central nervous system": 74.25310461855811, "Metastases to liver": 13.449048807140931, "Metastases to lung": 26.540211495558733, "Metastases to lymph nodes": 30.70553947850328, "Metastases to meninges": 59.98765145654069, "Metastases to skin": 77.26958700981854, "Metastasis": 11.510920545905874, "Metastatic malignant melanoma": 398.4923391902726, "Mucosal inflammation": 6.212920658691106, "Neoplasm": 9.161247639507623, "Neoplasm progression": 2.573619239728883, "Neutropenia": 3.155029599247391, "Non-small cell lung cancer": 13.876856684339211, "Oesophagitis": 10.19261524565018, "Panniculitis": 33.217689177885575, "Pemphigoid": 4.396866657824431, "Peripheral motor neuropathy": 45.268081504696575, "Peripheral sensory neuropathy": 10.448255366274385, "Pneumonitis": 8.993253828545377, "Polyneuropathy": 4.975738969265043, "Product use in unapproved indication": 5.758567984652719, "Pulmonary mass": 6.528449299665128, "Pyrexia": 2.485805349985104, "Rhabdomyolysis": 2.4133314712281444, "Sarcoidosis": 11.07554627931574, "Skin toxicity": 23.81092598567872, "Therapeutic response decreased": 6.037042566921579, "Therapy partial responder": 40.26413926134357, "Uveitis": 35.17084728831189}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/316.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/316.json
index c7f552db59d..d4329af56c2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/316.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/316.json
@@ -1 +1 @@
-{"Blood pressure increased ": 5.248971730957916, "Dizziness ": 2.4752661277959533, "Oedema peripheral ": 6.525972831883817, "Wrong technique in product usage process ": 13.0030641247141}
\ No newline at end of file
+{"Alanine aminotransferase increased": 2.321318364335335, "Anaemia": 3.8876991939893264, "Anuria": 10.4227031742893, "Ascites": 15.145343648683788, "Aspartate aminotransferase increased": 3.347161770117708, "Blindness": 2.910394317097917, "Blood bilirubin increased": 4.212472746770841, "Blood pressure decreased": 2.5938492580017813, "Bradycardia": 3.4923645149869484, "Cachexia": 24.54439833452568, "Chronic hepatitis C": 153.81904732081443, "Drug ineffective": 12.037542909302072, "Drug interaction": 3.134264434079593, "Drug resistance": 3.4354189144129426, "Duodenitis": 42.56792082718861, "Encephalopathy": 9.29907867292176, "Foot fracture": 6.381036602960899, "Gamma-glutamyltransferase increased": 4.354495610237676, "Gastritis": 5.466515698962911, "Genotype drug resistance test positive": 605.38686445476, "HIV infection": 94.41371560596392, "Hepatic cancer": 7.679390704427341, "Hepatic cirrhosis": 17.979465592968364, "Hepatic encephalopathy": 21.348871507731868, "Hepatic failure": 14.654868112645074, "Hepatitis C": 192.08409143741375, "Hepatocellular carcinoma": 58.54203475195683, "Hypophagia": 6.911485154585296, "Iridocyclitis": 28.21281420339721, "Liver transplant": 131.16569623171617, "Oesophagitis": 14.351529796099808, "Off label use": 2.2881385269215198, "Oral candidiasis": 7.061174146273633, "Platelet count increased": 10.086642594741278, "Proteinuria": 3.5154205941141465, "Pulmonary arterial hypertension": 14.949931443156368, "Refusal of treatment by patient": 164.33060163135738, "Renal impairment": 2.70500352558643, "Rhabdomyolysis": 2.1838001674814382, "Therapy non-responder": 4.3482792269548485, "Treatment failure": 75.98729350941606, "Treatment noncompliance": 4.588858163537847, "Viral mutation identified": 149.25009093444734, "Virologic failure": 106.23972147270464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/317.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/317.json
index f94b2c97fd2..40b3b1b19b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/317.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/317.json
@@ -1 +1 @@
-{"Anaemia ": 3.625522089039976, "Ascites ": 4.298027711624499, "Bradycardia ": 2.1425306527845995, "Cardiac failure ": 2.567011987479085, "Delusion ": 5.2476077109873644, "Disturbance in attention ": 2.031793699430957, "Drug ineffective ": 6.897747647714172, "Drug resistance ": 3.862540736610312, "Encephalopathy ": 4.7604117278802205, "Genotype drug resistance test positive ": 76.88646183118409, "Haematemesis ": 2.381789854589192, "Haemoglobin decreased ": 2.172476910017918, "Hepatic cancer ": 13.093020709827162, "Hepatic cirrhosis ": 15.425507515045556, "Hepatic encephalopathy ": 16.162011192807157, "Hepatic failure ": 3.512925606790343, "Hepatic neoplasm ": 33.68786281065437, "Hepatitis C ": 154.85679920233505, "Hepatitis C RNA positive ": 151.8364867932985, "Hepatitis C virus test positive ": 65.79974705440259, "Hepatocellular carcinoma ": 55.46603061317785, "Hepatorenal syndrome ": 35.420927228081126, "Hyperbilirubinaemia ": 16.030729118149914, "Insomnia ": 3.096398410062133, "Irritability ": 2.889726209090952, "Jaundice ": 3.660378907569706, "Liver disorder ": 2.1047147619145083, "Liver transplant ": 50.61370761165082, "Mood swings ": 3.988207913442861, "Nervousness ": 4.355902856228382, "Oesophageal varices haemorrhage ": 31.465047549163856, "Psychotic disorder ": 4.714687668640631, "Pulmonary arterial hypertension ": 13.100647152090543, "Septic shock ": 3.760529087791993, "Speech disorder ": 2.367067336722572, "Surgery ": 4.2862405217937285, "Therapy non-responder ": 3.9449106387315753, "Treatment failure ": 65.28348799198957, "Treatment noncompliance ": 3.1361711498141025, "Viral load increased ": 12.881783917569264, "Viral mutation identified ": 77.95247564998206, "Virologic failure ": 30.535854944315773}
\ No newline at end of file
+{"Acne": 135.4315883148184, "Alopecia": 24.52323786557943, "Condition aggravated": 12.896438077305426, "Drug ineffective": 4.067334332277076, "Incorrect route of product administration": 47.69434844439749, "Liver function test abnormal": 87.1935836430591, "Loss of personal independence in daily activities": 31.01333890972893, "Ovarian cyst": 614.8969261647052, "Overdose": 15.10407027085082, "Pain": 4.572390390290807, "Pneumonia": 12.394326730007208, "Product use issue": 14.168739995489528, "Rheumatoid arthritis": 23.010481461671752, "Sleep disorder due to general medical condition, insomnia type": 411.26380198328826, "Transplant dysfunction": 3214.066520857936, "Transplant rejection": 600.2111679254759}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/318.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/318.json
index e7df3f884e4..696aa2869fa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/318.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/318.json
@@ -1 +1 @@
-{"Arrhythmia ": 3.787587708056783, "Arterial occlusive disease ": 42.69625338462652, "Bronchitis ": 15.328287056032352, "Chronic obstructive pulmonary disease ": 48.60039458391499, "Dyspnoea ": 4.021099705085336, "Haemorrhage ": 2.949708418686076, "Heart rate increased ": 4.839791328308693, "Illness ": 7.168633491688431, "Intentional product misuse ": 8.952161062495813, "Off label use ": 2.064449570085352, "Pneumonia ": 5.551312507713237, "Product dose omission issue ": 7.461581735497777, "Tremor ": 3.217502171068173, "Weight decreased ": 3.316367341468318}
\ No newline at end of file
+{"Fall": 4.5275952778376976, "Febrile neutropenia": 17.857217806011302, "Neutropenia": 6.931576356294323, "Off label use": 2.534992983153972, "Pancytopenia": 11.229998603806642, "Platelet count decreased": 6.849634710478662, "Product use in unapproved indication": 5.013199718430815, "Weight decreased": 3.5838359404994424, "White blood cell count decreased": 7.00772534734014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/319.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/319.json
index 758bff89256..418bd55cfc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/319.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/319.json
@@ -1 +1 @@
-{"Abdominal distension ": 4.480299620257311, "Acute kidney injury ": 3.442823079862193, "Acute myocardial infarction ": 8.230450875353094, "Altered state of consciousness ": 2.625296757176017, "Blood pressure decreased ": 4.758641685074941, "Cardiac failure ": 4.303129724326497, "Cardiac failure chronic ": 28.612698340317383, "Cardiomegaly ": 20.67409226058214, "Cardiomyopathy ": 5.394555322726371, "Dehydration ": 2.547903577354684, "Diabetes mellitus ": 6.386148070055702, "Diabetes mellitus inadequate control ": 20.027312144058687, "Diabetic ketoacidosis ": 25.858499878737284, "Diabetic metabolic decompensation ": 42.34912395885505, "Disturbance in attention ": 2.8716951937684185, "Drug eruption ": 3.393848503760205, "Drug interaction ": 2.215206981461047, "Dyspnoea exertional ": 3.0759632911647574, "Ejection fraction decreased ": 12.036689799676948, "Emphysema ": 10.296138580794665, "Euglycaemic diabetic ketoacidosis ": 71.7024408889011, "Glomerular filtration rate decreased ": 8.49638488109364, "Glomerular filtration rate increased ": 115.4869166457034, "Glycosylated haemoglobin increased ": 6.146722992521417, "Hyperglycaemia ": 5.839174150484727, "Hyperkalaemia ": 5.789084522994558, "Hyperthyroidism ": 3.0558402557743243, "Hyperuricaemia ": 52.02265574909392, "Hypoglycaemia ": 10.995819153771272, "Hypoglycaemic coma ": 45.818997838559646, "Hypotension ": 2.9256352335213114, "Infarction ": 14.08792876526469, "Injury ": 3.757761137938656, "Ischaemic stroke ": 15.316692373302043, "Ketoacidosis ": 10.097327844507474, "Labelled drug-drug interaction issue ": 24.689699869269067, "Lactic acidosis ": 5.598691253071434, "Liver injury ": 4.863044443465836, "Metabolic acidosis ": 15.461530444811292, "Mitral valve incompetence ": 19.106363225878475, "Mobility decreased ": 2.3401497710040537, "Myocardial infarction ": 2.613407920118109, "Neuropathy peripheral ": 3.667015402622934, "Non-alcoholic fatty liver ": 490.2106149003097, "Obesity ": 17.28763761920976, "Oedema peripheral ": 5.058925727791796, "Onychoclasis ": 97.83932439009328, "Psoriasis ": 6.38472549246734, "Pulmonary hypertension ": 4.894571905108378, "Pulmonary oedema ": 7.93526264441068, "Renal impairment ": 3.637619176224221, "Right ventricular failure ": 21.902004383062728, "Therapeutic response decreased ": 3.1790997495259634, "Tricuspid valve incompetence ": 35.48981291633555, "Type 2 diabetes mellitus ": 4.25039460288018, "Type V hyperlipidaemia ": 419.682493202819, "Unresponsive to stimuli ": 5.1840069411430045, "Urinary tract infection ": 2.3658192235690345, "Ventricular extrasystoles ": 6.707882515398371, "Ventricular hypokinesia ": 38.78542489575379, "Ventricular tachycardia ": 6.499412033124952, "Weight decreased ": 4.5573218799078825, "Wrong technique in product usage process ": 2.320587206263502}
\ No newline at end of file
+{"Blood pressure increased": 5.248879615106186, "Dizziness": 2.475248944396232, "Oedema peripheral": 6.525811573834412, "Wrong technique in product usage process": 13.0030641247141}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/32.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/32.json
index 52dc9a97188..3488cb4a109 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/32.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/32.json
@@ -1 +1 @@
-{"Anti factor VIII antibody increased ": 1504.9310023749174, "Anti factor VIII antibody positive ": 709.2331216936611, "Anti factor VIII antibody test ": 1794.795778416135, "Cerebral haemorrhage ": 3.8508492116380815, "Contusion ": 6.771531811078156, "Extra dose administered ": 46.93094278082483, "Factor VIII inhibition ": 7454.559016309977, "Fall ": 3.152567935687556, "Haemarthrosis ": 667.7554723400546, "Haematemesis ": 3.758937820757549, "Haematoma ": 11.980213383208149, "Haematoma muscle ": 23.95071289970571, "Haematuria ": 2.94461079396561, "Haemorrhage ": 48.52981161493238, "Haemorrhage intracranial ": 9.704736643486026, "Haemorrhage subcutaneous ": 9.736029390613254, "Head injury ": 11.662746173364592, "Inhibiting antibodies ": 3940.9703485076943, "Inhibiting antibodies positive ": 1497.021142300464, "Injury ": 4.187367198535719, "Joint injury ": 24.11801714283509, "Joint swelling ": 3.1137597639486088, "Limb injury ": 20.54735479041749, "Mouth haemorrhage ": 34.60356212098903, "Muscle haemorrhage ": 168.5913638164659, "Road traffic accident ": 4.55197166552746, "Therapeutic product effect decreased ": 2.1669892705539557, "Vascular device infection ": 47.4278604348247}
\ No newline at end of file
+{"Acute kidney injury": 4.952206932327359, "Acute respiratory distress syndrome": 15.329073606999035, "Agranulocytosis": 6.929416770805925, "B-cell lymphoma": 71.83991164554432, "Blood creatinine increased": 4.260397932705378, "COVID-19 pneumonia": 17.882342427739424, "Confusional state": 2.0006864420226966, "Cytomegalovirus infection": 18.188974697057123, "Death": 2.7618291215284216, "Diabetes mellitus": 2.806091665188015, "Diarrhoea": 2.289830061107125, "Drug interaction": 5.434594985167591, "Foetal growth restriction": 29.970436453067997, "General physical health deterioration": 2.3728861876467917, "Hallucination": 2.717676761659514, "Hyperkalaemia": 2.9614691106978674, "Immunosuppressant drug level decreased": 139.76970210997496, "Immunosuppressant drug level increased": 203.08749041628212, "Kidney transplant rejection": 45.80172693848392, "Leukopenia": 5.1725678699526325, "Multiple organ dysfunction syndrome": 7.869716801234381, "Neutropenia": 4.755111375175452, "Pancreatitis acute": 8.629185471714257, "Pancytopenia": 5.2599519939128365, "Pyelonephritis": 24.11309473041598, "Sepsis": 2.5696905802727383, "Thrombocytopenia": 2.721671608307177, "Transplant rejection": 51.13837996140876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/320.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/320.json
index 5a3035436a4..2bc8c3a0c05 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/320.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/320.json
@@ -1 +1 @@
-{"Acute kidney injury ": 3.003182037754114, "Altered state of consciousness ": 5.509876812962887, "Antimicrobial susceptibility test resistant ": 1146.818714423247, "Arthritis bacterial ": 61.70225519680322, "Blood creatine phosphokinase increased ": 7.132789688702759, "C-reactive protein increased ": 2.576513694743252, "Candida infection ": 21.135313253024226, "Cellulitis ": 4.068436105211628, "Clostridium difficile infection ": 7.959074553631679, "Disseminated intravascular coagulation ": 8.684994398395828, "Drug dispensed to wrong patient ": 1786.848880883941, "Drug eruption ": 5.991722358882518, "Drug ineffective ": 3.0592522165537623, "Drug ineffective for unapproved indication ": 22.347690034401577, "Drug interaction ": 4.267442016397671, "Drug reaction with eosinophilia and systemic symptoms ": 23.59813482989423, "Drug resistance ": 16.96060549943664, "Endocarditis ": 66.15875443104805, "Eosinophilia ": 6.718209619446062, "Expired product administered ": 34.2054777324708, "Hypoxia ": 3.7053771029911298, "Infection ": 2.912448600450679, "Intentional product misuse ": 4.020798860586919, "Lactic acidosis ": 4.658532419402796, "Lower respiratory tract infection ": 17.48120855997858, "Minimum inhibitory concentration ": 5070.275694688478, "Multiple organ dysfunction syndrome ": 11.07517215059124, "Multiple-drug resistance ": 15.890956090397513, "Off label use ": 2.6137065087400124, "Oliguria ": 16.858437902920198, "Pancytopenia ": 3.454615316456632, "Pathogen resistance ": 81.02339386579516, "Product administration error ": 15.009462586872033, "Product dispensing error ": 42.9960251449162, "Product storage error ": 25.602519920043846, "Product use in unapproved indication ": 2.881204024361437, "Rash maculo-papular ": 2.087681680463793, "Renal impairment ": 2.209807430499996, "Respiratory failure ": 3.68585339018592, "Rhabdomyolysis ": 9.308087919250143, "Sepsis ": 3.9873940031212896, "Septic shock ": 13.23352250154996, "Staphylococcal bacteraemia ": 164.40288221150644, "Staphylococcal infection ": 39.31743736502168, "Therapeutic response delayed ": 385.6011702657819, "Therapy non-responder ": 21.41200674906068, "Toxic epidermal necrolysis ": 8.955312494502156, "Treatment failure ": 14.179412780989914, "Wrong patient received product ": 134.8817577338964, "Wrong product administered ": 30.46158083737492}
\ No newline at end of file
+{"Anaemia": 3.625522089039976, "Ascites": 4.298027711624499, "Bradycardia": 2.142463496181293, "Cardiac failure": 2.566777606469582, "Delusion": 5.2476077109873644, "Disturbance in attention": 2.031793699430957, "Drug ineffective": 6.89769658972396, "Drug resistance": 3.862540736610312, "Encephalopathy": 4.7604117278802205, "Genotype drug resistance test positive": 76.88646183118409, "Haematemesis": 2.381578611272152, "Haemoglobin decreased": 2.172476910017918, "Hepatic cancer": 13.093020709827162, "Hepatic cirrhosis": 15.425507515045556, "Hepatic encephalopathy": 16.162011192807157, "Hepatic failure": 3.512925606790343, "Hepatic neoplasm": 33.68786281065437, "Hepatitis C": 154.85679920233505, "Hepatitis C RNA positive": 151.8364867932985, "Hepatitis C virus test positive": 65.79974705440259, "Hepatocellular carcinoma": 55.46603061317785, "Hepatorenal syndrome": 35.420927228081126, "Hyperbilirubinaemia": 16.030729118149914, "Insomnia": 3.096398410062133, "Irritability": 2.8895881842654707, "Jaundice": 3.660378907569706, "Liver disorder": 2.1047147619145083, "Liver transplant": 50.61370761165082, "Mood swings": 3.988207913442861, "Nervousness": 4.355902856228382, "Oesophageal varices haemorrhage": 31.465047549163856, "Psychotic disorder": 4.714687668640631, "Pulmonary arterial hypertension": 13.100647152090543, "Septic shock": 3.760529087791993, "Speech disorder": 2.367067336722572, "Surgery": 4.2862405217937285, "Therapy non-responder": 3.944565888262305, "Treatment failure": 65.28348799198957, "Treatment noncompliance": 3.1361711498141025, "Viral load increased": 12.881783917569264, "Viral mutation identified": 77.95247564998206, "Virologic failure": 30.535854944315773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/321.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/321.json
index 5b43281b6d9..4b5cb844326 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/321.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/321.json
@@ -1 +1 @@
-{"Anaemia ": 4.734585531815524, "Aplastic anaemia ": 23.13578027934807, "Atrial fibrillation ": 3.092356399071226, "Bone pain ": 3.891300656337952, "Cardiac failure ": 2.293701102514334, "Cytomegalovirus infection reactivation ": 43.90331700365943, "Deep vein thrombosis ": 2.0410990548424874, "Febrile neutropenia ": 7.012886842356283, "Haematotoxicity ": 27.306766249685985, "Intentional product use issue ": 2.985059149369655, "Lethargy ": 5.012191801092992, "Localised infection ": 28.256979611010827, "Lower respiratory tract infection ": 7.665860095136718, "Myelosuppression ": 2.0854331433781645, "Neuropathy peripheral ": 4.153376586642948, "Neutropenia ": 9.867588953058178, "Neutrophil count decreased ": 4.480262656065535, "Off label use ": 4.785459416374513, "Oropharyngeal pain ": 3.2074090862458693, "Pancytopenia ": 2.353610609415271, "Plasma cell myeloma ": 110.3570070557018, "Plasma cell myeloma recurrent ": 136.46929935798, "Platelet count decreased ": 2.914323675077393, "Pleural effusion ": 2.800230079589462, "Pneumocystis jirovecii pneumonia ": 34.459013345949, "Pneumonia ": 7.878703734414014, "Renal impairment ": 3.537730413528343, "Respiratory tract infection ": 9.363441124372097, "Sepsis ": 4.556475204840668, "Thrombocytopenia ": 5.44442362925898, "Upper respiratory tract infection ": 5.713232229876285, "Urinary tract infection ": 3.5546271390207265}
\ No newline at end of file
+{"Arrhythmia": 3.787587708056783, "Arterial occlusive disease": 42.69625338462652, "Bronchitis": 15.327367620796863, "Chronic obstructive pulmonary disease": 48.60039458391499, "Dyspnoea": 4.0210399580613, "Haemorrhage": 2.949708418686076, "Heart rate increased": 4.839791328308693, "Illness": 7.168633491688431, "Intentional product misuse": 8.952161062495813, "Off label use": 2.0643682587685794, "Pneumonia": 5.551312507713237, "Product dose omission issue": 7.461581735497777, "Tremor": 3.217380635758366, "Weight decreased": 3.316367341468318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/322.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/322.json
index 6adb87d4e8b..3d2b9241e08 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/322.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/322.json
@@ -1 +1 @@
-{"Abdominal distension ": 19.936035137679664, "Abdominal pain ": 5.28044169436573, "Anaemia ": 5.072805980722283, "Analgesic therapy ": 505.3676511870972, "Aplasia pure red cell ": 26.41592018628307, "Appendicitis ": 141.54596667567208, "Appendicolith ": 482.6031003037765, "Ascites ": 45.03706912035207, "Bacterial infection ": 53.175941204490975, "Blood cholesterol increased ": 15.308342187836574, "Blood phosphorus increased ": 230.84390741085903, "Blood uric acid increased ": 80.88319461086844, "Cardiogenic shock ": 89.32334810185446, "Condition aggravated ": 4.316333227440547, "Constipation ": 10.923261731872126, "Diabetes mellitus ": 11.719148574124294, "Drug hypersensitivity ": 2.510450706629234, "Drug therapy ": 1909.175898647532, "Dry mouth ": 11.177851954948514, "Foetal exposure during pregnancy ": 3.572086143289717, "General physical health deterioration ": 16.443732437122936, "Hyponatraemia ": 26.794704673059627, "Incorrect route of product administration ": 54.897210869561945, "Intentional product misuse ": 10.035865815699998, "Low birth weight baby ": 17.210922654826184, "Multiple organ dysfunction syndrome ": 37.97844336770435, "Myasthenia gravis ": 101.68476605696192, "Neuralgia ": 17.514183820995754, "Off label use ": 4.110138066909038, "Premature baby ": 8.687828480005768, "Sepsis ": 18.35624504706132, "Sleep disorder therapy ": 17149.396838288594, "Stress ": 20.310307451906084, "Ventricular fibrillation ": 42.8886923875399}
\ No newline at end of file
+{"Abdominal distension": 4.480299620257311, "Acute kidney injury": 3.442823079862193, "Acute myocardial infarction": 8.230450875353094, "Altered state of consciousness": 2.625296757176017, "Blood pressure decreased": 4.758487161901079, "Cardiac failure": 4.302736751188912, "Cardiac failure chronic": 28.612698340317383, "Cardiomegaly": 20.67409226058214, "Cardiomyopathy": 5.394555322726371, "Dehydration": 2.5477675539109863, "Diabetes mellitus": 6.386148070055702, "Diabetes mellitus inadequate control": 20.027312144058687, "Diabetic ketoacidosis": 25.858499878737284, "Diabetic metabolic decompensation": 42.34912395885505, "Disturbance in attention": 2.8716951937684185, "Drug eruption": 3.393848503760205, "Drug interaction": 2.215206981461047, "Dyspnoea exertional": 3.0759632911647574, "Ejection fraction decreased": 12.036689799676948, "Emphysema": 10.296138580794665, "Euglycaemic diabetic ketoacidosis": 71.7024408889011, "Glomerular filtration rate decreased": 8.49638488109364, "Glomerular filtration rate increased": 115.4869166457034, "Glycosylated haemoglobin increased": 6.146722992521417, "Hyperglycaemia": 5.839174150484727, "Hyperkalaemia": 5.788285855777339, "Hyperthyroidism": 3.0555622525164186, "Hyperuricaemia": 52.02265574909392, "Hypoglycaemia": 10.9954473661268, "Hypoglycaemic coma": 45.818997838559646, "Hypotension": 2.9255675748374963, "Infarction": 14.08792876526469, "Injury": 3.7572156523060087, "Ischaemic stroke": 15.316692373302043, "Ketoacidosis": 10.097327844507474, "Labelled drug-drug interaction issue": 24.689699869269067, "Lactic acidosis": 5.598691253071434, "Liver injury": 4.863044443465836, "Metabolic acidosis": 15.461530444811292, "Mitral valve incompetence": 19.106363225878475, "Mobility decreased": 2.3401497710040537, "Myocardial infarction": 2.613407920118109, "Neuropathy peripheral": 3.666904038650652, "Non-alcoholic fatty liver": 490.2106149003097, "Obesity": 17.28763761920976, "Oedema peripheral": 5.05880062618003, "Onychoclasis": 97.83932439009328, "Psoriasis": 6.38472549246734, "Pulmonary hypertension": 4.894571905108378, "Pulmonary oedema": 7.934219779640464, "Renal impairment": 3.637619176224221, "Right ventricular failure": 21.902004383062728, "Therapeutic response decreased": 3.1790997495259634, "Tricuspid valve incompetence": 35.48981291633555, "Type 2 diabetes mellitus": 4.25039460288018, "Type V hyperlipidaemia": 419.682493202819, "Unresponsive to stimuli": 5.183436739823071, "Urinary tract infection": 2.3658192235690345, "Ventricular extrasystoles": 6.707882515398371, "Ventricular hypokinesia": 38.78542489575379, "Ventricular tachycardia": 6.499412033124952, "Weight decreased": 4.5573218799078825, "Wrong technique in product usage process": 2.320587206263502}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/323.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/323.json
index e147f0e4d9b..c95d7c8bbf7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/323.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/323.json
@@ -1 +1 @@
-{"Abortion induced ": 8.606587403070778, "Abortion spontaneous ": 3.973337641069544, "Acute kidney injury ": 2.184662463410167, "Adverse drug reaction ": 2.4703017974985664, "Ascites ": 3.265958140037682, "Benign prostatic hyperplasia ": 23.93434226255876, "Blood HIV RNA increased ": 112.31137603770236, "Blood alkaline phosphatase increased ": 2.0225237737088406, "Blood cholesterol increased ": 5.447698231408759, "Blood triglycerides increased ": 25.94930043054709, "Brain stem stroke ": 164.40142667332285, "CD4 lymphocytes decreased ": 52.85833010000207, "Cachexia ": 12.888059821691806, "Caesarean section ": 9.07706023739452, "Cerebral ventricle dilatation ": 85.94795592095674, "Congenital musculoskeletal disorder of skull ": 103.1479389574201, "Cushing's syndrome ": 19.14370275938481, "Drug interaction ": 6.590953689055403, "Drug resistance ": 18.23457458881037, "Duodenal ulcer ": 24.3667078257071, "Dyslipidaemia ": 9.211546746419312, "Exposure during pregnancy ": 8.258474821800872, "Foetal death ": 11.485077943161643, "Foetal exposure during pregnancy ": 9.174438520940107, "Foot fracture ": 3.751483312827532, "Gastric ulcer ": 8.859596542922949, "Gene mutation ": 57.87411781017406, "Genotype drug resistance test positive ": 38.93701901365275, "HIV infection ": 49.13240810702784, "HIV viraemia ": 657.6699485594878, "Hepatic cancer ": 9.530161096996478, "Hepatitis cholestatic ": 11.794282110757702, "Human immunodeficiency virus transmission ": 502.62623383061936, "Hyperlipidaemia ": 17.054909820445843, "Immune reconstitution inflammatory syndrome ": 153.63691266766077, "Immune reconstitution inflammatory syndrome associated tuberculosis ": 177.95585838105103, "Lactic acidosis ": 3.4829111833959803, "Live birth ": 10.06468039475834, "Low birth weight baby ": 12.501062023369682, "Maternal exposure during pregnancy ": 8.53356983614865, "Mental disorder ": 2.070139029757534, "Metabolic acidosis ": 2.463018969322534, "Nephropathy toxic ": 6.768534060700462, "Neuropathy peripheral ": 2.144363754289252, "No adverse event ": 11.8860103008112, "Oesophageal candidiasis ": 19.67147825298624, "Oral disorder ": 15.234661281625398, "Osteoporosis ": 3.1109798076540023, "Pathogen resistance ": 100.8737448008916, "Peripheral sensory neuropathy ": 10.5265978137022, "Pleocytosis ": 76.14576800980407, "Pneumocystis jirovecii pneumonia ": 26.9502989311732, "Premature baby ": 4.793131037156078, "Premature delivery ": 9.274468500126233, "Proteinuria ": 5.618582939795924, "Renal impairment ": 3.6820037493235898, "Skin exfoliation ": 2.2729067107993752, "Spina bifida ": 34.25068771593388, "Treatment failure ": 4.003533625580308, "Treatment noncompliance ": 26.909697345270796, "Type 2 diabetes mellitus ": 3.7856860679563913, "Viraemia ": 35.77081299102465, "Viral load increased ": 26.852048780969945, "Viral mutation identified ": 142.38259860508552, "Virologic failure ": 137.44067924120804}
\ No newline at end of file
+{"Acute kidney injury": 3.003182037754114, "Altered state of consciousness": 5.509876812962887, "Antimicrobial susceptibility test resistant": 1146.818714423247, "Arthritis bacterial": 61.70225519680322, "Blood creatine phosphokinase increased": 7.132789688702759, "C-reactive protein increased": 2.576513694743252, "Candida infection": 21.135313253024226, "Cellulitis": 4.068436105211628, "Clostridium difficile infection": 7.959074553631679, "Disseminated intravascular coagulation": 8.684994398395828, "Drug dispensed to wrong patient": 1786.848880883941, "Drug eruption": 5.991722358882518, "Drug ineffective": 3.0592295946520687, "Drug ineffective for unapproved indication": 22.347690034401577, "Drug interaction": 4.267442016397671, "Drug reaction with eosinophilia and systemic symptoms": 23.596180667483697, "Drug resistance": 16.96060549943664, "Endocarditis": 66.15875443104805, "Eosinophilia": 6.718209619446062, "Expired product administered": 34.2054777324708, "Hypoxia": 3.7053771029911298, "Infection": 2.912448600450679, "Intentional product misuse": 4.020798860586919, "Lactic acidosis": 4.658532419402796, "Lower respiratory tract infection": 17.48120855997858, "Minimum inhibitory concentration": 5070.275694688478, "Multiple organ dysfunction syndrome": 11.07517215059124, "Multiple-drug resistance": 15.890956090397513, "Off label use": 2.613603538876704, "Oliguria": 16.858437902920198, "Pancytopenia": 3.454615316456632, "Pathogen resistance": 81.02339386579516, "Product administration error": 15.008285073008134, "Product dispensing error": 42.9960251449162, "Product storage error": 25.602519920043846, "Product use in unapproved indication": 2.8811141561621785, "Rash maculo-papular": 2.087681680463793, "Renal impairment": 2.209807430499996, "Respiratory failure": 3.685549015296042, "Rhabdomyolysis": 9.308087919250143, "Sepsis": 3.9873940031212896, "Septic shock": 13.23352250154996, "Staphylococcal bacteraemia": 164.40288221150644, "Staphylococcal infection": 39.31743736502168, "Therapeutic response delayed": 385.6011702657819, "Therapy non-responder": 21.41013152700081, "Toxic epidermal necrolysis": 8.955312494502156, "Treatment failure": 14.179412780989914, "Wrong patient received product": 134.8817577338964, "Wrong product administered": 30.46158083737492}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/324.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/324.json
index 7cf8348884d..007b6261499 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/324.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/324.json
@@ -1 +1 @@
-{"Acute pulmonary oedema ": 5.268153293617144, "Adverse event ": 2.896361976859951, "Anaemia ": 2.519864053837227, "Anaphylactoid reaction ": 2.5474246826309743, "Asphyxia ": 7.798539548111271, "Atrial fibrillation ": 3.188454027293862, "Atrial flutter ": 4.740390194507171, "Bronchospasm ": 9.632793347678753, "COVID-19 pneumonia ": 2.265119647307373, "Cardiac failure acute ": 2.804596034246313, "Chest discomfort ": 2.702118680198537, "Coombs indirect test positive ": 586.978795038228, "Crossmatch incompatible ": 4305.221030728607, "Cytokine release syndrome ": 2.1422815053123103, "Cytomegalovirus infection ": 7.007128234211858, "Cytomegalovirus infection reactivation ": 4.630246963499437, "Cytopenia ": 10.739210544069191, "Disease progression ": 7.97960725762015, "Encephalopathy ": 2.022518263051156, "Extravasation ": 19.75494220537353, "Febrile neutropenia ": 4.633424286719122, "Granulocyte count decreased ": 11.924019192374526, "Haematotoxicity ": 6.67487551328717, "Haemoglobin decreased ": 2.495602543583451, "Haemolysis ": 2.3652028723529845, "Hepatitis B reactivation ": 4.779851875646584, "Hypercalcaemia ": 2.348415920305669, "Hyperpyrexia ": 3.3493200589099232, "Hypervolaemia ": 2.6873569924139105, "Hypogammaglobulinaemia ": 18.189020058063782, "Hypoxia ": 3.8504608357566528, "Incorrect drug administration rate ": 12.651436699663108, "Infection ": 3.3786757462722328, "Infusion related reaction ": 79.28832067209537, "Infusion site extravasation ": 12.423451496536437, "Intentional product use issue ": 9.932199209606177, "Laboratory test abnormal ": 3.033870076213724, "Laryngeal oedema ": 3.805211841234778, "Light chain analysis increased ": 211.9208540814577, "Lymphocyte count decreased ": 3.8959742743840735, "Lymphopenia ": 11.564370618507894, "Monoclonal immunoglobulin increased ": 203.9453988685196, "Monoclonal immunoglobulin present ": 85.2101406936284, "Myelosuppression ": 5.293475992428948, "Nasal congestion ": 3.133281544677238, "Nasal obstruction ": 10.54799599864986, "Neuropathy peripheral ": 7.852364833784499, "Neutropenia ": 6.393979625102623, "Neutrophil count decreased ": 6.268289605547695, "Off label use ": 4.510302882384245, "Oropharyngeal discomfort ": 2.3353420716768527, "Osteonecrosis of jaw ": 6.340162451585181, "Oxygen saturation decreased ": 7.820938050190069, "Pancytopenia ": 5.218177044952263, "Peripheral sensory neuropathy ": 5.617823365857957, "Plasma cell leukaemia ": 54.03659493762508, "Plasma cell myeloma ": 131.17081336307456, "Plasma cell myeloma recurrent ": 84.71844872614702, "Plasma cell myeloma refractory ": 50.34665769884432, "Plasmacytoma ": 76.77781212474392, "Platelet count decreased ": 4.655629941203153, "Pneumocystis jirovecii pneumonia ": 3.164763672908086, "Pneumonia ": 3.678319858610012, "Polyneuropathy ": 13.136839810009102, "Posterior reversible encephalopathy syndrome ": 3.54957101093443, "Product dose omission issue ": 2.0964229367515266, "Product use in unapproved indication ": 2.595606166844535, "Product use issue ": 4.576556047949117, "Pseudomyopia ": 214.1076754529604, "Respiratory disorder ": 2.398370254602616, "Respiratory distress ": 2.640232247015679, "Respiratory tract infection ": 2.1134895642540177, "Rhinorrhoea ": 3.3710487144258328, "Sepsis ": 3.7645373933112007, "Septic shock ": 3.717005618366607, "Sneezing ": 2.0162897187700253, "Staphylococcal sepsis ": 7.603985347213098, "Stem cell transplant ": 53.7192731154701, "Tachypnoea ": 7.098918515920892, "Temperature intolerance ": 20.89466903349048, "Throat irritation ": 2.277238179508255, "Thrombocytopenia ": 4.3281797993603455, "Thrombotic microangiopathy ": 2.99515742442458, "Transfusion ": 3.9783031878922097, "Transplant ": 19.27926988112287, "Troponin increased ": 2.244771514262742, "Tumour lysis syndrome ": 17.801571727913366, "Upper respiratory tract infection ": 2.3404623862602683, "Wheezing ": 2.8702297832722103, "White blood cell count decreased ": 3.266587948801061}
\ No newline at end of file
+{"Anaemia": 4.734585531815524, "Aplastic anaemia": 23.13578027934807, "Atrial fibrillation": 3.092271984967121, "Bone pain": 3.891300656337952, "Cardiac failure": 2.293491743893426, "Cytomegalovirus infection reactivation": 43.90331700365943, "Deep vein thrombosis": 2.0410990548424874, "Febrile neutropenia": 7.012886842356283, "Haematotoxicity": 27.306766249685985, "Intentional product use issue": 2.985059149369655, "Lethargy": 5.012191801092992, "Localised infection": 28.256979611010827, "Lower respiratory tract infection": 7.665860095136718, "Myelosuppression": 2.0854331433781645, "Neuropathy peripheral": 4.153250476470359, "Neutropenia": 9.86716426167776, "Neutrophil count decreased": 4.480262656065535, "Off label use": 4.785270858848182, "Oropharyngeal pain": 3.2074090862458693, "Pancytopenia": 2.353610609415271, "Plasma cell myeloma": 110.3570070557018, "Plasma cell myeloma recurrent": 136.46929935798, "Platelet count decreased": 2.914323675077393, "Pleural effusion": 2.799972282042932, "Pneumocystis jirovecii pneumonia": 34.459013345949, "Pneumonia": 7.878703734414014, "Renal impairment": 3.537730413528343, "Respiratory tract infection": 9.363441124372097, "Sepsis": 4.556475204840668, "Thrombocytopenia": 5.44391126257472, "Upper respiratory tract infection": 5.713232229876285, "Urinary tract infection": 3.5546271390207265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/325.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/325.json
index a6661697504..0a652e99cf7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/325.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/325.json
@@ -1 +1 @@
-{"Anaemia ": 5.168469495707128, "Drug interaction ": 7.348599026222348, "Hepatitis C ": 40.50535812993751}
\ No newline at end of file
+{"Abdominal distension": 19.936035137679664, "Abdominal pain": 5.28044169436573, "Anaemia": 5.072805980722283, "Analgesic therapy": 505.3676511870972, "Aplasia pure red cell": 26.41592018628307, "Appendicitis": 141.54596667567208, "Appendicolith": 482.6031003037765, "Ascites": 45.03706912035207, "Bacterial infection": 53.175941204490975, "Blood cholesterol increased": 15.308342187836574, "Blood phosphorus increased": 230.84390741085903, "Blood uric acid increased": 80.88319461086844, "Cardiogenic shock": 89.32334810185446, "Condition aggravated": 4.316333227440547, "Constipation": 10.923261731872126, "Diabetes mellitus": 11.719148574124294, "Drug hypersensitivity": 2.510450706629234, "Drug therapy": 1909.175898647532, "Dry mouth": 11.177851954948514, "Foetal exposure during pregnancy": 3.572086143289717, "General physical health deterioration": 16.443732437122936, "Hyponatraemia": 26.794704673059627, "Incorrect route of product administration": 54.897210869561945, "Intentional product misuse": 10.035865815699998, "Low birth weight baby": 17.210922654826184, "Multiple organ dysfunction syndrome": 37.97844336770435, "Myasthenia gravis": 101.68476605696192, "Neuralgia": 17.514183820995754, "Off label use": 4.109976128010038, "Premature baby": 8.687828480005768, "Sepsis": 18.35624504706132, "Sleep disorder therapy": 17149.396838288594, "Stress": 20.310307451906084, "Ventricular fibrillation": 42.8886923875399}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/326.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/326.json
index 85527a663d3..82fac29132d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/326.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/326.json
@@ -1 +1 @@
-{"Acne ": 6.5464473532426135, "Acquired gene mutation ": 74.04215963479666, "Acute lymphocytic leukaemia ": 49.39375675496954, "Acute lymphocytic leukaemia recurrent ": 199.56251423669676, "Acute myeloid leukaemia ": 4.706006480316533, "Acute myocardial infarction ": 4.2402718731439375, "Arterial occlusive disease ": 19.304223782686, "Atrial flutter ": 14.029232324717643, "Bacterial infection ": 8.000523460831253, "Blast cell crisis ": 332.5361763327955, "Blast crisis in myelogenous leukaemia ": 289.2587294832939, "Blood alkaline phosphatase increased ": 3.63460650735159, "Blood pressure systolic decreased ": 20.77244648872229, "Bone marrow failure ": 7.314273040132797, "Bone pain ": 3.153923791661148, "C-reactive protein decreased ": 134.67193232387604, "Cardiomegaly ": 8.784198340264332, "Cerebral vasoconstriction ": 170.97816419314975, "Cerebrovascular accident ": 2.220313248491585, "Chronic myeloid leukaemia ": 182.35477533878944, "Chronic myeloid leukaemia recurrent ": 598.3027199529947, "Cognitive disorder ": 2.285508096492271, "Cytogenetic analysis abnormal ": 936.66730643815, "Cytomegalovirus colitis ": 177.66352117147068, "Cytopenia ": 9.56926523026553, "Drug intolerance ": 21.696017872901862, "Drug resistance ": 55.84951292110906, "Dyspnoea exertional ": 4.38142812326102, "Ejection fraction abnormal ": 63.224074895130514, "Febrile neutropenia ": 2.202481132585026, "Fluid retention ": 2.48633285865932, "Gamma-glutamyltransferase increased ": 3.001164960339424, "Heart rate increased ": 2.3638012108761903, "Hepatotoxicity ": 2.997220448582712, "Hypercalcaemia ": 6.843970899264061, "Hypervolaemia ": 27.36786162335604, "Hypokinesia ": 6.810363740036559, "Intentional product use issue ": 2.5418357765786648, "International normalised ratio increased ": 2.079905076942145, "Ischaemic cardiomyopathy ": 27.773926467812952, "Left ventricular failure ": 26.891434496853503, "Leukocytosis ": 12.145605580698366, "Lipase increased ": 26.601097506718855, "Malignant neoplasm progression ": 7.228553289343166, "Mitral valve incompetence ": 11.946417822285056, "Muscle spasms ": 2.109364242685745, "Musculoskeletal pain ": 2.4133468589826985, "Myeloid leukaemia ": 138.31933612043383, "Myocardial ischaemia ": 33.602464866388445, "Neutrophilia ": 47.93547485481319, "Osteomyelitis ": 11.691476398155068, "Pancreatitis ": 5.33977684664884, "Pancytopenia ": 3.66827926951917, "Philadelphia chromosome positive ": 512.8557772777307, "Photosensitivity reaction ": 6.910562087939298, "Platelet count decreased ": 3.510906297573464, "Pleural effusion ": 23.185611889913705, "Proteinuria ": 2.612603248618689, "Pulmonary hypertension ": 19.216775396516987, "Rectal haemorrhage ": 4.753150628198638, "Right ventricular dysfunction ": 115.5225267784365, "Splenomegaly ": 7.765346958783179, "Supraventricular tachycardia ": 31.228357974255932, "Therapeutic response decreased ": 11.392688160475322, "Therapy non-responder ": 7.938366015314968, "Thrombocytopenia ": 3.071519888198953, "Toxicity to various agents ": 2.471776528658698, "Transient ischaemic attack ": 3.63460650735159, "Treatment failure ": 13.537682342806146, "Treatment noncompliance ": 4.429786961954401, "Urinary tract infection ": 3.019415064519037, "Vasospasm ": 73.74022813608545, "Ventricular tachycardia ": 5.100527383854425, "White blood cell count increased ": 4.24484686144784}
\ No newline at end of file
+{"Abortion induced": 8.596154161342085, "Abortion spontaneous": 3.968520056780525, "Acute kidney injury": 2.18201233631775, "Adverse drug reaction": 2.4673071989557864, "Ascites": 3.261998555537949, "Benign prostatic hyperplasia": 23.905324197867053, "Blood HIV RNA increased": 112.17517171113002, "Blood alkaline phosphatase increased": 2.020071989450817, "Blood cholesterol increased": 5.441091785304298, "Blood triglycerides increased": 25.917827223869256, "Brain stem stroke": 164.20212667360337, "CD4 lymphocytes decreased": 52.79424608060109, "Cachexia": 12.872436828718955, "Caesarean section": 9.066056670700966, "Cerebral ventricle dilatation": 85.84375758659355, "Congenital musculoskeletal disorder of skull": 103.0228886161948, "Cushing's syndrome": 19.120494904902607, "Drug interaction": 6.634772920095775, "Drug resistance": 18.21245276451576, "Duodenal ulcer": 24.337162714480083, "Dyslipidaemia": 9.200380150104095, "Exposure during pregnancy": 8.248453744185538, "Foetal death": 11.471153671176488, "Foetal exposure during pregnancy": 9.16330567227559, "Foot fracture": 3.746935734761056, "Gastric ulcer": 8.842963579811087, "Gene mutation": 57.80395433588703, "Genotype drug resistance test positive": 38.88981273607956, "HIV infection": 49.07284387317901, "HIV viraemia": 656.8725332715977, "Hepatic cancer": 9.518606446442176, "Hepatitis cholestatic": 11.779982094125865, "Human immunodeficiency virus transmission": 502.0169625443496, "Hyperlipidaemia": 17.034228607124298, "Immune reconstitution inflammatory syndrome": 153.4503916083696, "Immune reconstitution inflammatory syndrome associated tuberculosis": 177.74013742551838, "Lactic acidosis": 3.4786883114918337, "Live birth": 10.052478716992622, "Low birth weight baby": 12.485905070491832, "Maternal exposure during pregnancy": 8.523215049811226, "Mental disorder": 2.067629590194567, "Metabolic acidosis": 2.4600331993125453, "Nephropathy toxic": 6.760328574636772, "Neuropathy peripheral": 2.1416985345118973, "No adverse event": 11.871595454158456, "Oesophageal candidiasis": 19.64763115173859, "Oral disorder": 15.21619191116634, "Osteoporosis": 3.107206829727565, "Pathogen resistance": 100.75133174855743, "Peripheral sensory neuropathy": 10.513837397476994, "Pleocytosis": 76.05346425004969, "Pneumocystis jirovecii pneumonia": 26.9176148350109, "Premature baby": 4.787319472087996, "Premature delivery": 9.26322385850158, "Proteinuria": 5.61177053335957, "Renal impairment": 3.677537527919732, "Skin exfoliation": 2.2701512671184947, "Spina bifida": 34.209163900383466, "Treatment failure": 3.99867859778663, "Treatment noncompliance": 26.877044456513342, "Type 2 diabetes mellitus": 3.7810967937569946, "Viraemia": 35.727451482308105, "Viral load increased": 26.819489002087117, "Viral mutation identified": 142.20989885177767, "Virologic failure": 137.27391245378325}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/327.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/327.json
index 7a39a95d337..4c596544564 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/327.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/327.json
@@ -1 +1 @@
-{"Abdominal pain upper ": 7.91321796122384}
\ No newline at end of file
+{"Acute pulmonary oedema": 5.268153293617144, "Adverse event": 2.896361976859951, "Anaemia": 2.519864053837227, "Anaphylactoid reaction": 2.5474246826309743, "Asphyxia": 7.798539548111271, "Atrial fibrillation": 3.1883668217578416, "Atrial flutter": 4.740390194507171, "Bronchospasm": 9.632793347678753, "COVID-19 pneumonia": 2.265119647307373, "Cardiac failure acute": 2.804596034246313, "Chest discomfort": 2.702023682036761, "Coombs indirect test positive": 586.978795038228, "Crossmatch incompatible": 4305.221030728607, "Cytokine release syndrome": 2.1422815053123103, "Cytomegalovirus infection": 7.007128234211858, "Cytomegalovirus infection reactivation": 4.630246963499437, "Cytopenia": 10.730610068526158, "Disease progression": 7.97960725762015, "Encephalopathy": 2.022518263051156, "Extravasation": 19.75494220537353, "Febrile neutropenia": 4.633424286719122, "Granulocyte count decreased": 11.924019192374526, "Haematotoxicity": 6.67487551328717, "Haemoglobin decreased": 2.495602543583451, "Haemolysis": 2.3652028723529845, "Hepatitis B reactivation": 4.779851875646584, "Hypercalcaemia": 2.348415920305669, "Hyperpyrexia": 3.3493200589099232, "Hypervolaemia": 2.6873569924139105, "Hypogammaglobulinaemia": 18.189020058063782, "Hypoxia": 3.8504608357566528, "Incorrect drug administration rate": 12.651436699663108, "Infection": 3.3786757462722328, "Infusion related reaction": 79.28832067209537, "Infusion site extravasation": 12.423451496536437, "Intentional product use issue": 9.932199209606177, "Laboratory test abnormal": 3.033870076213724, "Laryngeal oedema": 3.805211841234778, "Light chain analysis increased": 211.9208540814577, "Lymphocyte count decreased": 3.8959742743840735, "Lymphopenia": 11.564370618507894, "Monoclonal immunoglobulin increased": 203.9453988685196, "Monoclonal immunoglobulin present": 85.2101406936284, "Myelosuppression": 5.293475992428948, "Nasal congestion": 3.133281544677238, "Nasal obstruction": 10.54799599864986, "Neuropathy peripheral": 7.852125211279572, "Neutropenia": 6.393703514075393, "Neutrophil count decreased": 6.268289605547695, "Off label use": 4.510124710945754, "Oropharyngeal discomfort": 2.3353420716768527, "Osteonecrosis of jaw": 6.340162451585181, "Oxygen saturation decreased": 7.820517445707471, "Pancytopenia": 5.218177044952263, "Peripheral sensory neuropathy": 5.617823365857957, "Plasma cell leukaemia": 54.03659493762508, "Plasma cell myeloma": 131.17081336307456, "Plasma cell myeloma recurrent": 84.71844872614702, "Plasma cell myeloma refractory": 50.34665769884432, "Plasmacytoma": 76.77781212474392, "Platelet count decreased": 4.655629941203153, "Pneumocystis jirovecii pneumonia": 3.164763672908086, "Pneumonia": 3.678319858610012, "Polyneuropathy": 13.136839810009102, "Posterior reversible encephalopathy syndrome": 3.54957101093443, "Product dose omission issue": 2.0964229367515266, "Product use in unapproved indication": 2.5955250911527994, "Product use issue": 4.576556047949117, "Pseudomyopia": 214.1076754529604, "Respiratory disorder": 2.398370254602616, "Respiratory distress": 2.640232247015679, "Respiratory tract infection": 2.1134895642540177, "Rhinorrhoea": 3.3710487144258328, "Sepsis": 3.7645373933112007, "Septic shock": 3.717005618366607, "Sneezing": 2.0162897187700253, "Staphylococcal sepsis": 7.603985347213098, "Stem cell transplant": 53.7192731154701, "Tachypnoea": 7.09790460121499, "Temperature intolerance": 20.89466903349048, "Throat irritation": 2.277238179508255, "Thrombocytopenia": 4.327771498509002, "Thrombotic microangiopathy": 2.99515742442458, "Transfusion": 3.9783031878922097, "Transplant": 19.27926988112287, "Troponin increased": 2.244771514262742, "Tumour lysis syndrome": 17.801571727913366, "Upper respiratory tract infection": 2.3404623862602683, "Wheezing": 2.8701154299439664, "White blood cell count decreased": 3.266587948801061}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/328.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/328.json
index de2d4a49377..563704bb1d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/328.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/328.json
@@ -1 +1 @@
-{"Death ": 19.576393406500067, "Neutropenia ": 124.38926742241983, "Pneumonia ": 87.82472351569312}
\ No newline at end of file
+{"Anaemia": 5.168469495707128, "Drug interaction": 7.348599026222348, "Hepatitis C": 40.50535812993751}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/329.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/329.json
index 9036f4c6c12..2fa7547018e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/329.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/329.json
@@ -1 +1 @@
-{"Asthma ": 25.290203684662824, "Blood test abnormal ": 50.85673159442715, "Chronic obstructive pulmonary disease ": 12.746683007749708, "Cough ": 3.2967735777529983, "Drug intolerance ": 5.803328697589451, "Dyspnoea ": 3.0699542357107457, "Full blood count abnormal ": 44.69104487310736, "Gastrooesophageal reflux disease ": 19.83139000450531, "Inflammatory bowel disease ": 167.861493551287, "Loss of personal independence in daily activities ": 16.424389136078307, "Nasopharyngitis ": 6.79905919571834, "Obstructive airways disorder ": 81.25887567309145, "Pneumonia ": 2.1384378514288143, "Therapeutic product effect decreased ": 13.85321575408534, "Therapeutic product effect incomplete ": 16.78249805602869, "Weight decreased ": 4.09835450614966, "Weight increased ": 6.561338307726702, "Wheezing ": 30.30733704577424}
\ No newline at end of file
+{"Acne": 6.5464473532426135, "Acquired gene mutation": 74.04215963479666, "Acute lymphocytic leukaemia": 49.39375675496954, "Acute lymphocytic leukaemia recurrent": 199.56251423669676, "Acute myeloid leukaemia": 4.706006480316533, "Acute myocardial infarction": 4.2402718731439375, "Arterial occlusive disease": 19.304223782686, "Atrial flutter": 14.029232324717643, "Bacterial infection": 8.000523460831253, "Blast cell crisis": 332.5361763327955, "Blast crisis in myelogenous leukaemia": 289.2587294832939, "Blood alkaline phosphatase increased": 3.63460650735159, "Blood pressure systolic decreased": 20.77244648872229, "Bone marrow failure": 7.314273040132797, "Bone pain": 3.153923791661148, "C-reactive protein decreased": 134.67193232387604, "Cardiomegaly": 8.784198340264332, "Cerebral vasoconstriction": 170.97816419314975, "Cerebrovascular accident": 2.220273226129115, "Chronic myeloid leukaemia": 182.35477533878944, "Chronic myeloid leukaemia recurrent": 598.3027199529947, "Cognitive disorder": 2.285508096492271, "Cytogenetic analysis abnormal": 936.66730643815, "Cytomegalovirus colitis": 177.66352117147068, "Cytopenia": 9.561644754730668, "Drug intolerance": 21.696017872901862, "Drug resistance": 55.84951292110906, "Dyspnoea exertional": 4.38142812326102, "Ejection fraction abnormal": 63.224074895130514, "Febrile neutropenia": 2.202481132585026, "Fluid retention": 2.48633285865932, "Gamma-glutamyltransferase increased": 3.001164960339424, "Heart rate increased": 2.3638012108761903, "Hepatotoxicity": 2.997220448582712, "Hypercalcaemia": 6.843970899264061, "Hypervolaemia": 27.36786162335604, "Hypokinesia": 6.810363740036559, "Intentional product use issue": 2.5418357765786648, "International normalised ratio increased": 2.079905076942145, "Ischaemic cardiomyopathy": 27.773926467812952, "Left ventricular failure": 26.891434496853503, "Leukocytosis": 12.145605580698366, "Lipase increased": 26.601097506718855, "Malignant neoplasm progression": 7.228553289343166, "Mitral valve incompetence": 11.946417822285056, "Muscle spasms": 2.109364242685745, "Musculoskeletal pain": 2.4133468589826985, "Myeloid leukaemia": 138.31933612043383, "Myocardial ischaemia": 33.602464866388445, "Neutrophilia": 47.93547485481319, "Osteomyelitis": 11.691476398155068, "Pancreatitis": 5.33977684664884, "Pancytopenia": 3.66827926951917, "Philadelphia chromosome positive": 512.8557772777307, "Photosensitivity reaction": 6.910562087939298, "Platelet count decreased": 3.510906297573464, "Pleural effusion": 23.183467152057027, "Proteinuria": 2.612603248618689, "Pulmonary hypertension": 19.216775396516987, "Rectal haemorrhage": 4.753150628198638, "Right ventricular dysfunction": 115.5225267784365, "Splenomegaly": 7.765346958783179, "Supraventricular tachycardia": 31.228357974255932, "Therapeutic response decreased": 11.392688160475322, "Therapy non-responder": 7.937671622791848, "Thrombocytopenia": 3.0712308064351275, "Toxicity to various agents": 2.471776528658698, "Transient ischaemic attack": 3.63460650735159, "Treatment failure": 13.537682342806146, "Treatment noncompliance": 4.429786961954401, "Urinary tract infection": 3.019415064519037, "Vasospasm": 73.74022813608545, "Ventricular tachycardia": 5.100527383854425, "White blood cell count increased": 4.244033656790984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/33.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/33.json
index 6c1e0c33057..df1a207ffc6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/33.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/33.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 3.0262828814170697, "Abortion spontaneous ": 3.154990370031147, "Accidental overdose ": 3.019200393850785, "Acute generalised exanthematous pustulosis ": 5.787070142423634, "Aggression ": 8.842251938517835, "Agitation ": 2.593329495027245, "Angioedema ": 3.1305181833441957, "Blindness transient ": 5.960531138311021, "Cholestasis ": 3.666054413651656, "Dermatitis bullous ": 5.271831188305839, "Drug ineffective for unapproved indication ": 2.2692270825389507, "Drug reaction with eosinophilia and systemic symptoms ": 3.5391214777247915, "Dry mouth ": 5.158309234616886, "Eczema ": 5.5363913969215535, "Electrocardiogram QT prolonged ": 2.332980052472557, "Eosinophilia ": 5.639074145365703, "Expired product administered ": 4.147121098159371, "Exposure during pregnancy ": 2.673384896300315, "Face oedema ": 2.8179169035086065, "Fall ": 2.163979147450486, "Fear ": 2.5483737387212764, "Foot deformity ": 5.604969355190742, "Foot prosthesis user ": 3003.0361538269094, "Gestational hypertension ": 90.61058667821294, "Hallucination ": 2.6019695466685318, "Hallucination, auditory ": 5.613270771771385, "Hallucination, visual ": 3.322449323183662, "Hepatic cytolysis ": 9.83462487345191, "Hepatitis ": 3.4655079080431586, "Hepatitis cholestatic ": 3.1688140637342554, "Hypocalcaemia ": 3.032559941017974, "Increased appetite ": 5.567778954914356, "Lower limb fracture ": 9.6073443976647, "Mood altered ": 2.451858359423866, "Nervousness ": 2.322218633761326, "Nightmare ": 3.311381588240087, "No adverse event ": 5.246008939884965, "Oral discomfort ": 3.320583462891775, "Overdose ": 2.0582694107737427, "Pancreatitis acute ": 2.340191892769533, "Paranoia ": 4.265530906808739, "Peripheral artery thrombosis ": 17.77187774494437, "Pharyngeal disorder ": 25.24293533690124, "Photosensitivity reaction ": 4.271289004097845, "Premature baby ": 2.379524819785799, "Premature delivery ": 3.0167678870271355, "Prescribed overdose ": 2.6415720808597025, "Product availability issue ": 6.906315116320731, "Product prescribing error ": 3.1329042308590327, "Product prescribing issue ": 15.2101453494379, "Product use in unapproved indication ": 2.0808299618657764, "Product use issue ": 3.10136072162112, "Productive cough ": 2.161706115810852, "Prurigo ": 46.58721842142428, "Pruritus ": 2.361609636502864, "Psychomotor hyperactivity ": 5.578688781074466, "Psychotic disorder ": 2.172102247015496, "Rash maculo-papular ": 3.801016806334382, "Rash morbilliform ": 2.220691224974386, "Rash pustular ": 5.554646601551784, "Respiratory distress ": 2.2982164399976583, "Restlessness ": 2.034319388879596, "Rhabdomyolysis ": 4.131883655065865, "Somnolence ": 4.629284085290047, "Suicide attempt ": 3.833707595281592, "Swelling face ": 2.224771964737958, "Tachycardia ": 2.6469209713109727, "Therapeutic product ineffective ": 13.03801580911446, "Toxic skin eruption ": 3.860998897638804, "Tubulointerstitial nephritis ": 2.1961648679194203, "Urticaria ": 2.022772139277583, "Vasculitis ": 5.043565772697956}
\ No newline at end of file
+{"Anti factor VIII antibody increased": 1504.9310023749174, "Anti factor VIII antibody positive": 709.2331216936611, "Anti factor VIII antibody test": 1794.795778416135, "Cerebral haemorrhage": 3.8508492116380815, "Contusion": 6.771531811078156, "Extra dose administered": 46.93094278082483, "Factor VIII inhibition": 7454.559016309977, "Fall": 3.152487096218796, "Haemarthrosis": 667.7554723400546, "Haematemesis": 3.7586044117679593, "Haematoma": 11.980213383208149, "Haematoma muscle": 23.95071289970571, "Haematuria": 2.94461079396561, "Haemorrhage": 48.52981161493238, "Haemorrhage intracranial": 9.704736643486026, "Haemorrhage subcutaneous": 9.736029390613254, "Head injury": 11.662746173364592, "Inhibiting antibodies": 3940.9703485076943, "Inhibiting antibodies positive": 1497.021142300464, "Injury": 4.186759350287434, "Joint injury": 24.11801714283509, "Joint swelling": 3.1137597639486088, "Limb injury": 20.54735479041749, "Mouth haemorrhage": 34.60356212098903, "Muscle haemorrhage": 168.5913638164659, "Road traffic accident": 4.55197166552746, "Therapeutic product effect decreased": 2.1669892705539557, "Vascular device infection": 47.4278604348247}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/330.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/330.json
index a3ed204a563..1831f7ab942 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/330.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/330.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 64.1466668154165, "Anaemia ": 2.773600248157204, "Febrile neutropenia ": 22.974699239047236, "Infection ": 4.098102477356623, "Myelodysplastic syndrome ": 36.72531265495387, "Myelosuppression ": 32.22196203941578, "Neutropenia ": 4.120542324768252, "Neutrophil count decreased ": 5.360803457249633, "Oedema peripheral ": 3.350266980608194, "Off label use ": 5.198290546056645, "Pancytopenia ": 11.807840480875372, "Platelet count decreased ": 2.888023534767349, "Pneumonia ": 2.2095648492553663, "Product use in unapproved indication ": 3.4035108444085265, "Thrombocytopenia ": 2.9335260498024884, "White blood cell count decreased ": 4.757543114170407}
\ No newline at end of file
+{"Abdominal pain upper": 7.91321796122384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/331.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/331.json
index 33f729a706e..0a1be596699 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/331.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/331.json
@@ -1 +1 @@
-{"Haemoglobin decreased ": 12.837422319633935, "Platelet count decreased ": 7.421775372156706}
\ No newline at end of file
+{"Death": 19.576393406500067, "Neutropenia": 124.38391473863868, "Pneumonia": 87.82472351569312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/332.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/332.json
index 47e47925333..6705e6cebe5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/332.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/332.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 21.37375107424446, "Altered state of consciousness ": 5.130072330182727, "Ascites ": 8.375447960336, "Blood bilirubin increased ": 8.40632416116314, "Cerebral haemorrhage ": 8.521165245272234, "Condition aggravated ": 2.65076977535152, "Cystitis haemorrhagic ": 116.9428865386252, "Death ": 2.3846036722228083, "Disease progression ": 8.015597979624063, "Epistaxis ": 4.479242223399748, "Febrile neutropenia ": 3.649380583156115, "Gastric haemorrhage ": 17.818560609472588, "Gastrointestinal haemorrhage ": 23.35457233548314, "Graft versus host disease ": 72.64573373980406, "Haematochezia ": 5.002377133548935, "Haematuria ": 7.7623825337670675, "Haemorrhage ": 8.510115711550345, "Hepatic failure ": 7.872684492667658, "Hypotension ": 12.27976733642542, "Infection ": 2.733157101792721, "Lower gastrointestinal haemorrhage ": 31.192443568856344, "Melaena ": 11.40631664311037, "Mouth haemorrhage ": 26.962058141958032, "Multiple organ dysfunction syndrome ": 75.27726498668905, "Off label use ": 10.415596874125876, "Pulmonary alveolar haemorrhage ": 106.68041045205912, "Pulmonary haemorrhage ": 87.19483393321273, "Renal failure ": 3.230789069083278, "Respiratory failure ": 10.165010755103184, "Sepsis ": 10.96405135699253, "Septic shock ": 17.19408229592849, "Subdural haematoma ": 11.830100610499509, "Thrombotic microangiopathy ": 51.15663056011521, "Upper gastrointestinal haemorrhage ": 16.253181953656846, "Venoocclusive disease ": 456.3790143771198, "Venoocclusive liver disease ": 648.445316678196}
\ No newline at end of file
+{"Asthma": 25.290203684662824, "Blood test abnormal": 50.85673159442715, "Chronic obstructive pulmonary disease": 12.746683007749708, "Cough": 3.2967430013488928, "Drug intolerance": 5.803328697589451, "Dyspnoea": 3.0699086272874894, "Full blood count abnormal": 44.69104487310736, "Gastrooesophageal reflux disease": 19.83139000450531, "Inflammatory bowel disease": 167.861493551287, "Loss of personal independence in daily activities": 16.424389136078307, "Nasopharyngitis": 6.798541204081533, "Obstructive airways disorder": 81.25887567309145, "Pneumonia": 2.1384378514288143, "Therapeutic product effect decreased": 13.85321575408534, "Therapeutic product effect incomplete": 16.78249805602869, "Weight decreased": 4.09835450614966, "Weight increased": 6.561338307726702, "Wheezing": 30.306131037981448}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/333.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/333.json
index 9e26dfeeb6e..d24788be9a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/333.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/333.json
@@ -1 +1 @@
-{}
\ No newline at end of file
+{"Acute myeloid leukaemia": 64.1466668154165, "Anaemia": 2.773600248157204, "Febrile neutropenia": 22.974699239047236, "Infection": 4.098102477356623, "Myelodysplastic syndrome": 36.72531265495387, "Myelosuppression": 32.22196203941578, "Neutropenia": 4.12036513377674, "Neutrophil count decreased": 5.360803457249633, "Oedema peripheral": 3.350184193097859, "Off label use": 5.198085775365695, "Pancytopenia": 11.807840480875372, "Platelet count decreased": 2.888023534767349, "Pneumonia": 2.2095648492553663, "Product use in unapproved indication": 3.403404710142926, "Thrombocytopenia": 2.933250105155909, "White blood cell count decreased": 4.757543114170407}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/334.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/334.json
index 6f407e9d1f9..a537f7216b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/334.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/334.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 3.405563244573649, "Alcohol abuse ": 25.62701757663471, "Alcohol poisoning ": 54.9834279945252, "Anaemia ": 6.120177669540603, "Aortic arteriosclerosis ": 28.39991469915388, "Arrhythmia ": 2.039099155055584, "Aspartate aminotransferase increased ": 6.72876353109185, "Blood albumin decreased ": 23.40173086900297, "Blood alkaline phosphatase increased ": 2.078750332025528, "Blood bilirubin increased ": 4.261407411350907, "Blood calcium decreased ": 28.8577423156231, "Blood chloride decreased ": 42.32635729167484, "Blood creatinine increased ": 4.342163333465987, "Blood potassium decreased ": 6.9238733864126285, "Blood sodium decreased ": 11.16753490058625, "Blood thyroid stimulating hormone increased ": 7.788137702732822, "Blood urea increased ": 3.247060573801644, "Bone tuberculosis ": 211.4616179789929, "Bundle branch block left ": 13.986871751063044, "Cardiopulmonary failure ": 18.20601560147, "Chronic hepatitis C ": 84.48300349248355, "Chronic obstructive pulmonary disease ": 3.729251718997103, "Drug reaction with eosinophilia and systemic symptoms ": 6.907986199416337, "Drug resistance ": 3.2004237402802573, "Drug-induced liver injury ": 4.205598728586133, "Dyspnoea exertional ": 4.268086469977132, "Eating disorder ": 6.702979451741325, "Electrocardiogram QT prolonged ": 39.073722321132486, "Electrolyte imbalance ": 12.277859677625385, "Eye swelling ": 2.412843267848349, "Gamma-glutamyltransferase increased ": 9.24921827736326, "Gastroenteritis ": 14.736930203599782, "General physical health deterioration ": 2.110181968587744, "Generalised tonic-clonic seizure ": 5.136273980007629, "HIV infection ": 69.40456006323075, "Haemoglobin decreased ": 7.422906295406824, "Haemoptysis ": 3.0335211794686545, "Hallucination, visual ": 2.828570343338615, "Hepatic enzyme increased ": 6.460598504299959, "Hepatic failure ": 3.441675655874743, "Hepatitis ": 2.6335387304733926, "Hepatitis toxic ": 24.296871103636636, "Hepatotoxicity ": 5.850847030484843, "Hypnopompic hallucination ": 726.6622874169204, "Hypoalbuminaemia ": 11.386066880600126, "Hypocalcaemia ": 7.928129374143202, "Hypokalaemia ": 7.562096794244004, "Hypomagnesaemia ": 11.311169249808838, "Hypothyroidism ": 4.614435957586953, "Incorrect product administration duration ": 93.08773083028922, "Intentional product use issue ": 13.289884381988626, "Lethargy ": 2.526978350067973, "Mental disorder ": 2.98590434709295, "Metabolic acidosis ": 2.2356882101608258, "Nephropathy toxic ": 4.955711867891541, "Neuropathy peripheral ": 5.197840976420573, "Oesophageal candidiasis ": 24.628368010155995, "Off label use ": 2.597788267326985, "Oral candidiasis ": 10.854896403765474, "Otitis media ": 22.79196815930085, "Phobia ": 93.89526946675883, "Platelet count decreased ": 4.231463195108359, "Pneumothorax ": 6.737830220635362, "Polyneuropathy ": 4.708063363811717, "Product use in unapproved indication ": 2.065351696525883, "Product use issue ": 5.792457569391681, "Psychotic disorder ": 2.834763831293116, "Pulmonary tuberculosis ": 20.908291992416935, "Respiratory distress ": 2.729394763641804, "Respiratory failure ": 7.719117333273918, "Seizure ": 2.3762823622854707, "Sinus tachycardia ": 6.6353804990705205, "Tinea infection ": 111.79143234276958, "Treatment noncompliance ": 6.030996350635517, "Tuberculosis ": 31.188292699759064, "Underdose ": 8.350310861689435, "Urinary incontinence ": 2.964045100296247, "Vomiting ": 3.105659917760229, "White blood cell count increased ": 2.3241128681456606}
\ No newline at end of file
+{"Haemoglobin decreased": 12.837422319633935, "Platelet count decreased": 7.421775372156706}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/335.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/335.json
index f21f2acbf3c..77b90afd529 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/335.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/335.json
@@ -1 +1 @@
-{"Weight increased ": 50.380842379226486}
\ No newline at end of file
+{"Acute myeloid leukaemia": 21.37375107424446, "Altered state of consciousness": 5.130072330182727, "Ascites": 8.375447960336, "Blood bilirubin increased": 8.40632416116314, "Cerebral haemorrhage": 8.521165245272234, "Condition aggravated": 2.65076977535152, "Cystitis haemorrhagic": 116.9428865386252, "Death": 2.3846036722228083, "Disease progression": 8.015597979624063, "Epistaxis": 4.479242223399748, "Febrile neutropenia": 3.649380583156115, "Gastric haemorrhage": 17.818560609472588, "Gastrointestinal haemorrhage": 23.35457233548314, "Graft versus host disease": 72.64573373980406, "Haematochezia": 5.001882453042298, "Haematuria": 7.7623825337670675, "Haemorrhage": 8.510115711550345, "Hepatic failure": 7.872684492667658, "Hypotension": 12.279483192066817, "Infection": 2.733157101792721, "Lower gastrointestinal haemorrhage": 31.192443568856344, "Melaena": 11.40484520389305, "Mouth haemorrhage": 26.962058141958032, "Multiple organ dysfunction syndrome": 75.27726498668905, "Off label use": 10.41518631836053, "Pulmonary alveolar haemorrhage": 106.68041045205912, "Pulmonary haemorrhage": 87.19483393321273, "Renal failure": 3.230789069083278, "Respiratory failure": 10.164170994724826, "Sepsis": 10.96405135699253, "Septic shock": 17.19408229592849, "Subdural haematoma": 11.830100610499509, "Thrombotic microangiopathy": 51.15663056011521, "Upper gastrointestinal haemorrhage": 16.24876588791565, "Venoocclusive disease": 456.3790143771198, "Venoocclusive liver disease": 648.445316678196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/336.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/336.json
index ccd0de80bf8..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/336.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/336.json
@@ -1 +1 @@
-{"Anaemia ": 2.4475412765198734, "Blood creatinine increased ": 6.356461844484439, "Blood urea increased ": 26.34738675984425, "Confusional state ": 3.070327544150323, "Depression ": 3.2789827227433053, "Electrocardiogram QT prolonged ": 64.12384229545944, "Haemoglobin decreased ": 5.441607201719993, "Hepatic function abnormal ": 7.170335901092754, "Hepatotoxicity ": 22.390869375384185, "Hypoaesthesia oral ": 18.55018265650824, "Incorrect product administration duration ": 48.88141291747056, "Insomnia ": 2.112522584101962, "Neuropathy peripheral ": 13.72454405272617, "Neutropenia ": 2.276193412336826, "Product use in unapproved indication ": 3.137272930435328, "Product use issue ": 7.21387344947387, "Tuberculosis ": 51.57525033759398, "Visual impairment ": 3.6410359803174464}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/337.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/337.json
index b81ed6282f4..57e3ff8278b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/337.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/337.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 3.469085456758264, "Anaemia ": 3.5449401576175035, "Aspartate aminotransferase increased ": 3.1289530340819973, "Atrioventricular block first degree ": 44.58159574087806, "Back pain ": 4.515222883434026, "Blood alkaline phosphatase increased ": 4.068678751703394, "Blood calcium increased ": 21.03030882339737, "Blood cholesterol decreased ": 127.25585428435734, "Blood creatine increased ": 20.313165597450908, "Blood potassium increased ": 6.328243870282749, "Blood urea increased ": 4.096522747734538, "Bone lesion ": 105.8441474386898, "Bone pain ": 3.847668578436301, "Bradykinesia ": 20.277515825425343, "Breast cancer ": 5.430666060399886, "Breast cancer metastatic ": 17.192373717274624, "Breast cancer recurrent ": 32.63378619914449, "Carbohydrate antigen 15-3 increased ": 115.4651345882878, "Cellulitis ": 2.3739034807456703, "Cognitive disorder ": 2.8873848975006706, "Decreased appetite ": 4.466917007901024, "Dementia ": 10.379835404757944, "Depression ": 2.2608074892830814, "Diabetes mellitus inadequate control ": 2.9057128299904025, "Diarrhoea ": 2.172331260506966, "Disease progression ": 5.385014409699721, "Dysuria ": 6.929501558249445, "Ejection fraction decreased ": 5.64644267530151, "Electrocardiogram QT prolonged ": 11.24752656752983, "Febrile neutropenia ": 2.286582056362342, "Gamma-glutamyltransferase increased ": 2.874228615359094, "Gastric polyps ": 48.31706299587351, "Gastroenteritis viral ": 16.33635949422196, "General physical health deterioration ": 2.6188303421834647, "Hepatic enzyme increased ": 2.137608101974109, "Hepatotoxicity ": 3.856622085120218, "Hiatus hernia ": 7.604055509230259, "Hypercalcaemia ": 5.607487301895458, "Hypocalcaemia ": 14.78450658727745, "Incorrect product administration duration ": 5.003583658567151, "Liver function test abnormal ": 15.638355665605555, "Malignant neoplasm progression ": 8.211590523692863, "Metastases to bone ": 63.03282663313394, "Metastases to central nervous system ": 6.587491386229211, "Metastases to liver ": 38.10326855860724, "Metastases to lung ": 15.123245947783852, "Metastases to lymph nodes ": 56.437294754440025, "Metastases to peritoneum ": 26.360779971070592, "Metastases to spine ": 61.8211325294319, "Mucosal inflammation ": 9.880017584135532, "Neoplasm progression ": 10.567728316547894, "Neutropenia ": 8.9469824070308, "Neutrophil count decreased ": 3.400075075485248, "Osteonecrosis of jaw ": 67.39420292653622, "Pleural effusion ": 3.3941981078152272, "Prostate cancer ": 7.172807603969819, "Prostatic specific antigen increased ": 13.005275668098822, "Stress cardiomyopathy ": 22.053231000965635, "Therapeutic response decreased ": 2.5901418770560047, "Therapy partial responder ": 10.429781614492136, "Transaminases increased ": 3.2932791141948923, "Tumour marker increased ": 20.024837824377897}
\ No newline at end of file
+{"Alanine aminotransferase increased": 3.405563244573649, "Alcohol abuse": 25.62701757663471, "Alcohol poisoning": 54.9834279945252, "Anaemia": 6.120177669540603, "Aortic arteriosclerosis": 28.39991469915388, "Arrhythmia": 2.039099155055584, "Aspartate aminotransferase increased": 6.72876353109185, "Blood albumin decreased": 23.40173086900297, "Blood alkaline phosphatase increased": 2.078750332025528, "Blood bilirubin increased": 4.261407411350907, "Blood calcium decreased": 28.8577423156231, "Blood chloride decreased": 42.32635729167484, "Blood creatinine increased": 4.342163333465987, "Blood potassium decreased": 6.9238733864126285, "Blood sodium decreased": 11.16753490058625, "Blood thyroid stimulating hormone increased": 7.788137702732822, "Blood urea increased": 3.247060573801644, "Bone tuberculosis": 211.4616179789929, "Bundle branch block left": 13.986871751063044, "Cardiopulmonary failure": 18.20601560147, "Chronic hepatitis C": 84.48300349248355, "Chronic obstructive pulmonary disease": 3.729251718997103, "Drug reaction with eosinophilia and systemic symptoms": 6.907415060223075, "Drug resistance": 3.2004237402802573, "Drug-induced liver injury": 4.205342253789225, "Dyspnoea exertional": 4.268086469977132, "Eating disorder": 6.702979451741325, "Electrocardiogram QT prolonged": 39.073722321132486, "Electrolyte imbalance": 12.277859677625385, "Eye swelling": 2.412843267848349, "Gamma-glutamyltransferase increased": 9.24921827736326, "Gastroenteritis": 14.736930203599782, "General physical health deterioration": 2.110181968587744, "Generalised tonic-clonic seizure": 5.136273980007629, "HIV infection": 69.40456006323075, "Haemoglobin decreased": 7.422906295406824, "Haemoptysis": 3.0335211794686545, "Hallucination, visual": 2.828570343338615, "Hepatic enzyme increased": 6.460598504299959, "Hepatic failure": 3.441675655874743, "Hepatitis": 2.6335387304733926, "Hepatitis toxic": 24.296871103636636, "Hepatotoxicity": 5.850847030484843, "Hypnopompic hallucination": 726.6622874169204, "Hypoalbuminaemia": 11.386066880600126, "Hypocalcaemia": 7.928129374143202, "Hypokalaemia": 7.562096794244004, "Hypomagnesaemia": 11.311169249808838, "Hypothyroidism": 4.614435957586953, "Incorrect product administration duration": 93.08773083028922, "Intentional product use issue": 13.289884381988626, "Lethargy": 2.526978350067973, "Mental disorder": 2.98590434709295, "Metabolic acidosis": 2.2356882101608258, "Nephropathy toxic": 4.955711867891541, "Neuropathy peripheral": 5.19768302553349, "Oesophageal candidiasis": 24.628368010155995, "Off label use": 2.5976858983164326, "Oral candidiasis": 10.854896403765474, "Otitis media": 22.79196815930085, "Phobia": 93.89526946675883, "Platelet count decreased": 4.231463195108359, "Pneumothorax": 6.737830220635362, "Polyneuropathy": 4.708063363811717, "Product use in unapproved indication": 2.0652872692667934, "Product use issue": 5.792457569391681, "Psychotic disorder": 2.834763831293116, "Pulmonary tuberculosis": 20.908291992416935, "Respiratory distress": 2.729394763641804, "Respiratory failure": 7.718479026501318, "Seizure": 2.3760188336483634, "Sinus tachycardia": 6.6353804990705205, "Tinea infection": 111.79143234276958, "Treatment noncompliance": 6.030996350635517, "Tuberculosis": 31.188292699759064, "Underdose": 8.350310861689435, "Urinary incontinence": 2.964045100296247, "Vomiting": 3.1056179968261097, "White blood cell count increased": 2.3236678106309725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/338.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/338.json
index 2cf7a26cd0e..e2e8ee49ae9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/338.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/338.json
@@ -1 +1 @@
-{"Abnormal dreams ": 5.25433925655206, "Adverse event ": 2.226888134868513, "Altered state of consciousness ": 3.1681226227730144, "Anencephaly ": 137.58390919058138, "Atypical mycobacterial infection ": 59.78808350513631, "Blindness ": 2.442932414071355, "Blood HIV RNA increased ": 152.8702349110133, "Blood cholesterol increased ": 3.451725268989537, "Blood triglycerides increased ": 9.10357511275836, "Bone density decreased ": 2.229346078968495, "Cleft lip and palate ": 61.899197137842, "Congenital anomaly ": 11.764958294092825, "Coronavirus infection ": 18.06784843576593, "Cytokine release syndrome ": 5.034159612622109, "Dementia ": 4.217723472858996, "Dental caries ": 13.010340473531096, "Diabetes mellitus ": 2.849910795103178, "Drug resistance ": 9.390049238320705, "Dysphagia ": 2.155240590810111, "Fat tissue increased ": 80.4350097828438, "Gastrointestinal disorder ": 2.8252742011729484, "Gastrointestinal tube insertion ": 103.9029424781775, "HIV infection ": 82.13567411867415, "HIV test positive ": 154.89261518741472, "Hepatitis C ": 3.2448239462563198, "Immune reconstitution inflammatory syndrome ": 67.9189795859046, "Kaposi's sarcoma ": 47.905623362700105, "Lipids increased ": 106.53451714813713, "Low density lipoprotein increased ": 27.64040309252692, "Lymphoma ": 9.143998226139692, "Mycobacterium avium complex infection ": 39.47881318032175, "Neural tube defect ": 65.42523578250851, "Neurotoxicity ": 8.714819067114021, "Osteopenia ": 2.8386089925677567, "Osteoporosis ": 2.990841928683331, "Pancreatitis ": 2.631736997926445, "Pneumocystis jirovecii pneumonia ": 10.607492205056912, "Post-traumatic stress disorder ": 40.6177379573548, "Renal disorder ": 4.828920875186944, "Renal impairment ": 5.319122519006234, "Sinusitis ": 2.1372414502498835, "Syphilis ": 116.42312442563582, "Treatment noncompliance ": 11.055109358215985, "Viral load increased ": 43.65226576249108, "Virologic failure ": 30.98274301988402, "Weight decreased ": 2.008572677562373, "Weight increased ": 6.697973130156867, "Wrong technique in product usage process ": 2.527997699987852}
\ No newline at end of file
+{"Weight increased": 50.380842379226486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/339.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/339.json
index 4271ca8e395..22b5d4535d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/339.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/339.json
@@ -1 +1 @@
-{"Abnormal weight gain ": 44.96482191199119, "Aggression ": 2.2133642558313658, "Aphonia ": 11.179078206059978, "Asthma ": 5.409335148203829, "Depressed mood ": 2.7432208911221894, "Dermatitis exfoliative generalised ": 7.623199009910531, "Disturbance in attention ": 2.0283881500139285, "Drug hypersensitivity ": 2.946506145206897, "Drug reaction with eosinophilia and systemic symptoms ": 2.3658860560926374, "Dry mouth ": 2.15119287518281, "Electrocardiogram QT prolonged ": 2.6230803387564854, "Eosinophilia ": 3.844574625483778, "Face oedema ": 2.386858346690652, "Full blood count abnormal ": 8.439381944953862, "Generalised tonic-clonic seizure ": 2.5828653294725097, "Hepatic cytolysis ": 2.5158029448369725, "Incorrect dose administered ": 3.005280615616549, "Increased appetite ": 8.575065830098017, "Intentional overdose ": 4.923887587801009, "Intentional self-injury ": 8.434215511454896, "Lip swelling ": 2.0017512776510054, "Loss of personal independence in daily activities ": 6.004930061983674, "Multiple organ dysfunction syndrome ": 2.172706433892237, "Neuralgia ": 2.360310786046996, "Nightmare ": 2.6705397704222027, "Oedema ": 2.050463468575645, "Overdose ": 2.921857486838308, "Palpitations ": 2.125269300558198, "Pancoast's syndrome ": 4182.342890189411, "Papule ": 6.877681052032816, "Paraesthesia oral ": 2.014524297634052, "Petit mal epilepsy ": 18.491660505131037, "Photosensitivity reaction ": 5.9867980874682, "Product prescribing error ": 6.887527920789664, "Product substitution issue ": 6.438806872786277, "Product use in unapproved indication ": 2.08807258665603, "Product use issue ": 2.900080254614198, "Productive cough ": 7.694851592706317, "Pruritus ": 2.2775029291853244, "Rash maculo-papular ": 2.8120161366622383, "Rash pruritic ": 2.1994532012948205, "Sleep apnoea syndrome ": 8.043705822563235, "Sleep disorder due to a general medical condition ": 23.36322839179094, "Somnolence ": 3.3077312639454184, "Speech disorder ": 3.6926575066760736, "Swelling face ": 2.000409859292987, "Swollen tongue ": 2.7625054080265263, "Tachycardia ": 2.090378938673532, "Therapeutic product effect incomplete ": 8.12869851958033, "Therapeutic response unexpected ": 6.18754248686704, "Upper respiratory tract infection ": 3.449905412019484, "Urticaria ": 3.219599444249587, "Weight increased ": 3.240443628515908, "Wheezing ": 9.892101836178927, "Wrong product administered ": 5.331284447257246}
\ No newline at end of file
+{"Anaemia": 2.4475412765198734, "Blood creatinine increased": 6.356461844484439, "Blood urea increased": 26.34738675984425, "Confusional state": 3.070327544150323, "Depression": 3.2789827227433053, "Electrocardiogram QT prolonged": 64.12384229545944, "Haemoglobin decreased": 5.441607201719993, "Hepatic function abnormal": 7.170335901092754, "Hepatotoxicity": 22.390869375384185, "Hypoaesthesia oral": 18.55018265650824, "Incorrect product administration duration": 48.88141291747056, "Insomnia": 2.112522584101962, "Neuropathy peripheral": 13.724127308340949, "Neutropenia": 2.2760955439812083, "Product use in unapproved indication": 3.1371751037633806, "Product use issue": 7.21387344947387, "Tuberculosis": 51.57525033759398, "Visual impairment": 3.6410359803174464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/34.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/34.json
index e988740700e..3a6f3f3824e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/34.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/34.json
@@ -1 +1 @@
-{"Diarrhoea ": 4.689983751911651, "Disease progression ": 23.84815653129202, "Drug resistance ": 46.1857950846204, "Malignant neoplasm progression ": 10.974094265330796, "Metastases to central nervous system ": 54.04114445315533, "Paronychia ": 245.1656015327333}
\ No newline at end of file
+{"Abnormal behaviour": 3.016131981903649, "Abortion spontaneous": 3.144407056197952, "Accidental overdose": 3.0090732507387963, "Acute generalised exanthematous pustulosis": 5.767660119085703, "Aggression": 8.812578498017116, "Agitation": 2.5846290667613965, "Angioedema": 3.120014127364198, "Blindness transient": 5.940539891273659, "Cholestasis": 3.653757280796487, "Dermatitis bullous": 5.254148823013673, "Drug ineffective for unapproved indication": 2.261616234141333, "Drug reaction with eosinophilia and systemic symptoms": 3.526958171317896, "Dry mouth": 5.140999527559454, "Eczema": 5.517817072753864, "Electrocardiogram QT prolonged": 2.325154226274264, "Eosinophilia": 5.620156441244753, "Expired product administered": 4.133211709464831, "Exposure during pregnancy": 2.664415396680807, "Face oedema": 2.8084643895895427, "Fall": 2.156661907247372, "Fear": 2.539826914797604, "Foot deformity": 5.586170639255544, "Foot prosthesis user": 2992.9661323418613, "Gestational hypertension": 90.30663702201907, "Hallucination": 2.5932401316823195, "Hallucination, auditory": 5.594442263832297, "Hallucination, visual": 3.311305008781135, "Hepatic cytolysis": 9.801625418596636, "Hepatitis": 3.453882512780276, "Hepatitis cholestatic": 3.1581863863512094, "Hypocalcaemia": 3.0223892372319776, "Increased appetite": 5.549103945383997, "Lower limb fracture": 9.57511657116676, "Mood altered": 2.443635101673599, "Nervousness": 2.3144294318440752, "Nightmare": 3.300273665338058, "No adverse event": 5.228411197443711, "Oral discomfort": 3.3094461135480917, "Overdose": 2.0513633387550465, "Pancreatitis acute": 2.3323422196112187, "Paranoia": 4.251224173395248, "Peripheral artery thrombosis": 17.712272065609987, "Pharyngeal disorder": 25.158272307803493, "Photosensitivity reaction": 4.256961882423221, "Premature baby": 2.371543499196505, "Premature delivery": 3.0066499867843164, "Prescribed overdose": 2.6327121579447144, "Product availability issue": 6.883150497184475, "Product prescribing error": 3.122396510697026, "Product prescribing issue": 15.159125114701895, "Product use in unapproved indication": 2.073783007499787, "Product use issue": 3.090954642249674, "Productive cough": 2.154455305948161, "Prurigo": 46.43096000575437, "Pruritus": 2.3536525416350447, "Psychomotor hyperactivity": 5.559014933000945, "Psychotic disorder": 2.1648167481074534, "Rash maculo-papular": 3.788264273179748, "Rash morbilliform": 2.213243393714444, "Rash pustular": 5.536016946949363, "Respiratory distress": 2.2905075644742032, "Restlessness": 2.0273885633136373, "Rhabdomyolysis": 4.118021162239319, "Somnolence": 4.613690653264381, "Suicide attempt": 3.8208440783096247, "Swelling face": 2.217308601403408, "Tachycardia": 2.6379708240277746, "Therapeutic product ineffective": 12.994288512854354, "Toxic skin eruption": 3.848048633759535, "Tubulointerstitial nephritis": 2.188799293986053, "Urticaria": 2.0404306244790784, "Vasculitis": 5.026648216200437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/340.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/340.json
index d7404931e11..44e4bc5deae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/340.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/340.json
@@ -1 +1 @@
-{"Hyperglycaemia ": 59.36372930017131, "Hypoglycaemia ": 21.92506809467372}
\ No newline at end of file
+{"Alanine aminotransferase increased": 3.469085456758264, "Anaemia": 3.5449401576175035, "Aspartate aminotransferase increased": 3.1289530340819973, "Atrioventricular block first degree": 44.58159574087806, "Back pain": 4.515222883434026, "Blood alkaline phosphatase increased": 4.068678751703394, "Blood calcium increased": 21.03030882339737, "Blood cholesterol decreased": 127.25585428435734, "Blood creatine increased": 20.313165597450908, "Blood potassium increased": 6.328243870282749, "Blood urea increased": 4.096522747734538, "Bone lesion": 105.8441474386898, "Bone pain": 3.847668578436301, "Bradykinesia": 20.277515825425343, "Breast cancer": 5.430666060399886, "Breast cancer metastatic": 17.192373717274624, "Breast cancer recurrent": 32.63378619914449, "Carbohydrate antigen 15-3 increased": 115.4651345882878, "Cellulitis": 2.3739034807456703, "Cognitive disorder": 2.8873848975006706, "Decreased appetite": 4.466873645391143, "Dementia": 10.379835404757944, "Depression": 2.2608074892830814, "Diabetes mellitus inadequate control": 2.9057128299904025, "Diarrhoea": 2.1723131250237917, "Disease progression": 5.385014409699721, "Dysuria": 6.929501558249445, "Ejection fraction decreased": 5.64644267530151, "Electrocardiogram QT prolonged": 11.24752656752983, "Febrile neutropenia": 2.286582056362342, "Gamma-glutamyltransferase increased": 2.874228615359094, "Gastric polyps": 48.31706299587351, "Gastroenteritis viral": 16.33635949422196, "General physical health deterioration": 2.6188303421834647, "Hepatic enzyme increased": 2.137608101974109, "Hepatotoxicity": 3.856622085120218, "Hiatus hernia": 7.604055509230259, "Hypercalcaemia": 5.607487301895458, "Hypocalcaemia": 14.78450658727745, "Incorrect product administration duration": 5.003583658567151, "Liver function test abnormal": 15.638355665605555, "Malignant neoplasm progression": 8.211590523692863, "Metastases to bone": 63.03282663313394, "Metastases to central nervous system": 6.587491386229211, "Metastases to liver": 38.10326855860724, "Metastases to lung": 15.123245947783852, "Metastases to lymph nodes": 56.437294754440025, "Metastases to peritoneum": 26.360779971070592, "Metastases to spine": 61.8211325294319, "Mucosal inflammation": 9.880017584135532, "Neoplasm progression": 10.567728316547894, "Neutropenia": 8.946597026591519, "Neutrophil count decreased": 3.400075075485248, "Osteonecrosis of jaw": 67.39420292653622, "Pleural effusion": 3.393885488908195, "Prostate cancer": 7.172807603969819, "Prostatic specific antigen increased": 13.005275668098822, "Stress cardiomyopathy": 22.053231000965635, "Therapeutic response decreased": 2.5901418770560047, "Therapy partial responder": 10.429781614492136, "Transaminases increased": 3.2930773825107083, "Tumour marker increased": 20.024837824377897}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/341.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/341.json
index 8cdd26d6833..e7481017b30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/341.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/341.json
@@ -1 +1 @@
-{"Abdominal abscess ": 4.130620441731502, "Acute generalised exanthematous pustulosis ": 2.7241377160235625, "Acute graft versus host disease ": 4.028276705264547, "Acute leukaemia ": 3.621903728955592, "Acute lymphocytic leukaemia ": 6.220345287342108, "Acute lymphocytic leukaemia recurrent ": 8.821967635439831, "Acute myeloid leukaemia ": 3.976809374618505, "Acute pulmonary oedema ": 2.868006946523296, "Acute respiratory distress syndrome ": 2.978169948242065, "Acute respiratory failure ": 3.3362800928455103, "Adenoviral hepatitis ": 33.84639287822629, "Adenovirus infection ": 4.158450733666188, "Adrenal insufficiency ": 2.764855564979181, "Adult T-cell lymphoma/leukaemia ": 21.542497454520117, "Allergy test negative ": 64.30802692677703, "Amyloidosis ": 7.698644359007879, "Anaphylactic reaction ": 2.7661810063802044, "Anaphylactic shock ": 3.6087063386861833, "Anaphylactoid shock ": 10.887872550506422, "Antinuclear antibody positive ": 2.8132376218259, "Apgar score low ": 3.3918928028152635, "Aspergillus infection ": 10.402015594875046, "Atelectasis ": 5.011152585098555, "B-cell lymphoma recurrent ": 35.52400942881861, "Bacteraemia ": 3.914875550691824, "Bacterial infection ": 2.78245281216752, "Bacterial sepsis ": 4.269094541303519, "Biliary colic ": 3.930677299317784, "Blood disorder ": 3.12477553573266, "Blood fibrinogen decreased ": 5.652027845801441, "Blood gases abnormal ": 27.086967440957697, "Blood immunoglobulin G increased ": 5.41268101783985, "Blood lactate dehydrogenase increased ": 2.8922586845236564, "Blood lactic acid increased ": 5.075206923498662, "Bone lesion ": 7.5374123627980065, "Bone marrow failure ": 2.546357660358261, "Bradycardia foetal ": 4.245773985337802, "Brain abscess ": 7.215293244777227, "Brain herniation ": 2.9301287044821622, "Brain oedema ": 5.059762258463214, "Breech presentation ": 9.202093282503254, "Bronchial wall thickening ": 12.038923102175795, "Bronchopulmonary aspergillosis ": 12.308115489229042, "Bronchospasm ": 3.0233596803325407, "COVID-19 pneumonia ": 4.713779535524051, "CSF oligoclonal band present ": 62.248037504330085, "Candida infection ": 4.102949968995659, "Cardiac dysfunction ": 3.48688488441041, "Cardiac failure ": 2.1338163557211223, "Cardio-respiratory arrest ": 2.2332003278149486, "Cardiomegaly ": 2.005164110781153, "Cardiotoxicity ": 4.376885719455959, "Cardiovascular insufficiency ": 8.870738848548678, "Cataract subcapsular ": 15.365270294327734, "Cell marker increased ": 63.48473717304628, "Cell-mediated cytotoxicity ": 259.57356725092893, "Cellulitis ": 2.495316253822397, "Central nervous system lesion ": 5.163146596272349, "Central nervous system vasculitis ": 7.549605090733313, "Chronic graft versus host disease ": 2.1893186620971488, "Chronic lymphocytic leukaemia recurrent ": 11.562296381116036, "Clonic convulsion ": 3.641951468477932, "Clostridium difficile colitis ": 4.556810577087086, "Clostridium test positive ": 3.279313032348664, "Coma scale abnormal ": 3.113776279073339, "Computerised tomogram thorax abnormal ": 19.381929803373566, "Corneal disorder ": 8.739561011373798, "Corneal infiltrates ": 17.68565594347568, "Corneal oedema ": 6.267210427992417, "Corneal perforation ": 13.440651301634317, "Cryptococcosis ": 17.69061819323598, "Cushing's syndrome ": 2.305299583378042, "Cystitis haemorrhagic ": 2.5748017398969987, "Cytokine release syndrome ": 3.653095420792632, "Cytomegalovirus chorioretinitis ": 13.397115501426963, "Cytomegalovirus infection ": 3.5737760299059693, "Cytomegalovirus infection reactivation ": 5.005234043528828, "Cytopenia ": 9.822803176679155, "Deafness bilateral ": 3.015704647640087, "Deep vein thrombosis ": 2.050174562664356, "Diabetes insipidus ": 2.223835925107398, "Diastolic dysfunction ": 2.592745173485102, "Differentiation syndrome ": 12.34487330368347, "Diffuse large B-cell lymphoma ": 12.26780926600238, "Diffuse large B-cell lymphoma recurrent ": 25.393054013737864, "Diffuse large B-cell lymphoma refractory ": 26.700252151645184, "Disease progression ": 6.355838725557665, "Disease recurrence ": 2.5756799258711207, "Disseminated cryptococcosis ": 22.331520793197928, "Disseminated tuberculosis ": 7.844528668331018, "Drug clearance decreased ": 12.770183216085057, "Drug ineffective for unapproved indication ": 3.822502038601015, "Drug resistance ": 2.8804475710244724, "Ecthyma ": 22.90318644797652, "Embolic stroke ": 2.025825239845729, "Embolism ": 3.7394650602255, "Encephalitis ": 2.536917728165244, "Encephalopathy ": 2.0056400845430837, "Endophthalmitis ": 6.643884540522487, "Engraftment syndrome ": 54.12105346112561, "Enterococcal infection ": 5.63388162505178, "Enterocolitis ": 3.920765325097416, "Eosinophil count abnormal ": 10.01910061325164, "Epstein-Barr virus infection ": 2.246561999745265, "Escherichia bacteraemia ": 5.557893424063658, "Escherichia infection ": 3.113776279073339, "Escherichia sepsis ": 13.393057887307467, "Exophthalmos ": 3.1570632376240986, "Exposure during pregnancy ": 2.1565354828860306, "Faeces soft ": 2.213127954856789, "Failure to thrive ": 2.933536706382696, "Febrile bone marrow aplasia ": 7.274988606907375, "Febrile neutropenia ": 11.238676483698516, "Foetal distress syndrome ": 5.385572987717242, "Foetal exposure during pregnancy ": 3.6758098919873463, "Foetal growth restriction ": 6.874809424165415, "Foetal hypokinesia ": 7.534699617903125, "Follicular lymphoma ": 15.589793899208374, "Food poisoning ": 3.975919377901615, "Full blood count abnormal ": 2.0046528464244373, "Full blood count decreased ": 4.7653327088863815, "Fusarium infection ": 11.579274969526171, "Gastrointestinal inflammation ": 5.315448401256777, "Gastrointestinal necrosis ": 4.014330847842955, "Gastrointestinal perforation ": 2.213774126933728, "Gene mutation ": 10.460209424592335, "Haematotoxicity ": 4.177160855861352, "Haemodynamic instability ": 4.522160790291756, "Haemophagocytic lymphohistiocytosis ": 6.631100710643286, "Haemorrhoidal haemorrhage ": 2.0084453982898096, "Hepatic cytolysis ": 2.454616603880561, "Hepatic mass ": 3.6865592018792928, "Hepatitis B reactivation ": 11.16293026474227, "Hepatomegaly ": 2.2145979194151817, "Hepatosplenomegaly ": 2.696924539385122, "Herpes simplex encephalitis ": 33.339552058082646, "Hiccups ": 3.0719607239476834, "Hydrocephalus ": 5.229250910004191, "Hyperaemia ": 2.3627001535164878, "Hyperbilirubinaemia ": 2.529004150628658, "Hypercapnia ": 2.49655652406694, "Hyperthermia malignant ": 2.4602311831937564, "Hypertonic bladder ": 4.910122293747853, "Hypertransaminasaemia ": 2.4084965664063818, "Hypertriglyceridaemia ": 4.142055566238585, "Hypervolaemia ": 2.9397792575712067, "Hypocalcaemia ": 2.595050792624215, "Hypofibrinogenaemia ": 6.548779357266675, "Hypogammaglobulinaemia ": 9.88775939603276, "Hypopyon ": 15.033950482812074, "Hypotension ": 2.3023963663212563, "Hypoventilation ": 3.932546430844932, "Hypovolaemia ": 2.575047791369834, "Hypoxia ": 3.3513604497961764, "Hypoxic-ischaemic encephalopathy ": 2.746147720263091, "Ileus paralytic ": 2.350763621930446, "Immunosuppression ": 2.878827955960284, "Infection ": 2.8162433887863134, "Intestinal perforation ": 3.0023856313370945, "Keratoconus ": 29.43380923749087, "Keratopathy ": 9.379329769038405, "Klebsiella bacteraemia ": 9.443932765713411, "Klebsiella infection ": 10.976030207850355, "Klebsiella sepsis ": 11.051284174282197, "Large intestine perforation ": 3.573436807280728, "Laryngospasm ": 2.501408092742924, "Leukocytosis ": 2.6152985389337187, "Light chain analysis increased ": 43.01342858391224, "Live birth ": 6.5158864372304, "Liver abscess ": 2.864475806966906, "Low birth weight baby ": 7.413601751008866, "Lung abscess ": 6.040423370051107, "Lung consolidation ": 3.434866768682372, "Lung infiltration ": 2.769056280144776, "Lung opacity ": 5.427698759405109, "Lymphopenia ": 7.590006305188066, "Macule ": 3.737861339238013, "Madarosis ": 3.414606412778061, "Maternal exposure during pregnancy ": 2.3210288984604035, "Meningitis ": 2.8334366671711573, "Meningitis cryptococcal ": 7.818018911247948, "Meningitis tuberculous ": 26.543622274472067, "Mesothelioma ": 33.10717474191843, "Metabolic acidosis ": 2.11532608318124, "Metastases to bone ": 2.3885674742849763, "Metastasis ": 2.127094175150375, "Mitochondrial DNA mutation ": 140.37039197993863, "Mixed liver injury ": 3.3701055919535987, "Molluscum contagiosum ": 15.00024975303728, "Mucormycosis ": 11.967548179451574, "Mucosal inflammation ": 3.907924431932402, "Multiple organ dysfunction syndrome ": 4.893857759065851, "Multiple-drug resistance ": 4.617778664636292, "Myelodysplastic syndrome ": 6.3629723083324405, "Myelosuppression ": 4.441662516911432, "Myoclonus ": 3.263760722752866, "Myopathy ": 2.471734612230572, "Nasal polyps ": 2.392485884452181, "Necrosis ": 3.0226152572819998, "Negative pressure pulmonary oedema ": 31.14163769891865, "Neonatal asphyxia ": 6.225551588790206, "Neonatal respiratory distress ": 6.013483005204564, "Neonatal respiratory distress syndrome ": 9.666951865279842, "Neonatal tachypnoea ": 28.496191624361337, "Neoplasm recurrence ": 2.741032110547338, "Neoplasm skin ": 6.592449898519988, "Neuropathy peripheral ": 5.90290288785575, "Neurotoxicity ": 2.212188367002649, "Neutropenia ": 3.645862601420019, "Neutropenic colitis ": 13.086143321138335, "Neutropenic sepsis ": 15.536810774416166, "Neutrophil count decreased ": 2.9083634881719256, "Neutrophilia ": 4.9973430520409385, "Nikolsky's sign ": 5.431982103444282, "Non-Hodgkin's lymphoma ": 2.7672545661177304, "Normal newborn ": 4.5706632322473695, "Oesophageal stenosis ": 4.443102338622094, "Off label use ": 2.76835473699995, "Oligohydramnios ": 3.1002916826363176, "Oliguria ": 2.0176712126055905, "Oral mucosa erosion ": 4.372826671755049, "Oral pain ": 2.0661099463228787, "Organ failure ": 3.03616761981253, "Osteomyelitis ": 2.252321052507341, "Osteonecrosis of jaw ": 3.844903863000716, "PO2 decreased ": 4.789511835591069, "Pancreatitis necrotising ": 2.1113548783793994, "Pancytopenia ": 4.536571299964305, "Paradoxical drug reaction ": 5.088742267003961, "Paraplegia ": 2.556019997829242, "Partial seizures ": 4.320960673856503, "Patent ductus arteriosus ": 2.6984252007597034, "Pathological fracture ": 4.900137601318927, "Peptic ulcer perforation ": 32.01743501687865, "Peripheral sensorimotor neuropathy ": 6.050556624600754, "Peripheral sensory neuropathy ": 4.819338183055592, "Peritonitis ": 2.48752275553548, "Peroneal nerve palsy ": 2.7458977960224944, "Plasma cell leukaemia ": 32.8993387242471, "Plasma cell myeloma ": 32.54864684551133, "Plasma cell myeloma recurrent ": 65.36531828380281, "Plasma cell myeloma refractory ": 125.20869105062272, "Plasmacytoma ": 31.2116566885422, "Platelet count decreased ": 2.396173369073395, "Platelet disorder ": 3.2083217914490456, "Pleocytosis ": 17.672185714803042, "Pneumocystis jirovecii pneumonia ": 8.15847604581049, "Pneumomediastinum ": 13.122434125717852, "Pneumonia ": 2.7421103860474614, "Pneumonia bacterial ": 4.1438033194214325, "Pneumonia cytomegaloviral ": 5.918473356083501, "Pneumonia fungal ": 7.701276323980196, "Pneumonia klebsiella ": 8.676261447654184, "Pneumothorax ": 3.788054047904079, "Polyneuropathy ": 3.4112238870047693, "Post procedural hypotension ": 36.44921523683357, "Posterior reversible encephalopathy syndrome ": 4.975472679193486, "Pre-eclampsia ": 2.730073160099671, "Pregnancy ": 2.0175715456179266, "Premature baby ": 8.904621416655322, "Premature delivery ": 7.769951733531802, "Premature labour ": 3.7535544870881794, "Procedural hypotension ": 13.566224474182846, "Procedural nausea ": 40.97070936748767, "Procedural vomiting ": 36.59828765358079, "Product use in unapproved indication ": 2.421297119049458, "Progressive multifocal leukoencephalopathy ": 6.673065806855803, "Propofol infusion syndrome ": 10.389235100926498, "Prostate cancer metastatic ": 3.499165893191574, "Protein total decreased ": 2.0582087950586083, "Pseudomonal sepsis ": 7.035359288062929, "Pseudomonas infection ": 6.617214001138983, "Pulmonary haemorrhage ": 5.065146352759211, "Pulmonary tuberculosis ": 2.6569342191727223, "Pulseless electrical activity ": 2.4729562542430847, "Purpura senile ": 22.567870136316973, "Quadriplegia ": 4.816473021289911, "Resorption bone increased ": 30.384538905424407, "Respiratory acidosis ": 3.0560990789729097, "Respiratory failure ": 3.3813762133615466, "Reye's syndrome ": 41.56394602037711, "Second primary malignancy ": 2.058259686700416, "Sense of oppression ": 2.1616747697305048, "Sepsis ": 4.525773325240006, "Septic shock ": 5.612215983418823, "Shock ": 2.4498908774641093, "Skin abrasion ": 3.3740446283076952, "Skin lesion ": 2.0889860783053176, "Skin mass ": 2.876574846541846, "Sleep disorder due to a general medical condition ": 2.0481557647160296, "Soft tissue necrosis ": 10.947501307617369, "Spina bifida ": 2.5860478093969523, "Staphylococcal bacteraemia ": 5.937573221561912, "Staphylococcal infection ": 2.4063704825053667, "Staphylococcal sepsis ": 2.2084225157174915, "Status epilepticus ": 3.2885190921244374, "Steroid diabetes ": 7.5867552321682625, "Streptococcal infection ": 3.197194006509636, "Stridor ": 3.2539639021004136, "Strongyloidiasis ": 52.51102740603742, "Subcutaneous emphysema ": 11.839374203600183, "Substance-induced psychotic disorder ": 5.315356197710391, "Systemic candida ": 6.78452591572543, "Systemic mycosis ": 6.428180304624633, "Tachypnoea ": 4.236357949203008, "Tarsal tunnel syndrome ": 33.369830107623706, "Tetany ": 4.409035809830213, "Therapeutic response decreased ": 2.30462599334402, "Therapy non-responder ": 4.149429038144135, "Therapy partial responder ": 5.6667891551650245, "Thrombocytopenia ": 3.248952010887363, "Thrombotic microangiopathy ": 2.305742017448785, "Tonic clonic movements ": 5.192241620809898, "Toxic epidermal necrolysis ": 3.3265093497102813, "Transaminases abnormal ": 11.42676618840779, "Tuberculoma of central nervous system ": 25.811735876102677, "Tuberculosis of central nervous system ": 43.1944194736409, "Tumour lysis syndrome ": 10.714436601276576, "Type I hypersensitivity ": 7.268901896268634, "Ulcerative keratitis ": 4.965966507886051, "VIth nerve paralysis ": 5.794511894901075, "Varicella zoster virus infection ": 3.2738665202140567, "Vestibular disorder ": 3.2434289973379284, "Visual acuity reduced ": 2.2924034765118444}
\ No newline at end of file
+{"Abnormal dreams": 5.25433925655206, "Adverse event": 2.226888134868513, "Altered state of consciousness": 3.1681226227730144, "Anencephaly": 137.58390919058138, "Atypical mycobacterial infection": 59.78808350513631, "Blindness": 2.442932414071355, "Blood HIV RNA increased": 152.8702349110133, "Blood cholesterol increased": 3.451725268989537, "Blood triglycerides increased": 9.10357511275836, "Bone density decreased": 2.229346078968495, "Cleft lip and palate": 61.899197137842, "Congenital anomaly": 11.764958294092825, "Coronavirus infection": 18.06784843576593, "Cytokine release syndrome": 5.034159612622109, "Dementia": 4.217723472858996, "Dental caries": 13.010340473531096, "Diabetes mellitus": 2.849910795103178, "Drug resistance": 9.390049238320705, "Dysphagia": 2.155240590810111, "Fat tissue increased": 80.4350097828438, "Gastrointestinal disorder": 2.825185223467736, "Gastrointestinal tube insertion": 103.9029424781775, "HIV infection": 82.13567411867415, "HIV test positive": 154.89261518741472, "Hepatitis C": 3.2448239462563198, "Immune reconstitution inflammatory syndrome": 67.9189795859046, "Kaposi's sarcoma": 47.905623362700105, "Lipids increased": 106.53451714813713, "Low density lipoprotein increased": 27.64040309252692, "Lymphoma": 9.143998226139692, "Mycobacterium avium complex infection": 39.47881318032175, "Neural tube defect": 65.42523578250851, "Neurotoxicity": 8.714819067114021, "Osteopenia": 2.8386089925677567, "Osteoporosis": 2.990841928683331, "Pancreatitis": 2.631736997926445, "Pneumocystis jirovecii pneumonia": 10.607492205056912, "Post-traumatic stress disorder": 40.6177379573548, "Renal disorder": 4.82820827961819, "Renal impairment": 5.319122519006234, "Sinusitis": 2.1372414502498835, "Syphilis": 116.42312442563582, "Treatment noncompliance": 11.055109358215985, "Viral load increased": 43.65226576249108, "Virologic failure": 30.98274301988402, "Weight decreased": 2.008572677562373, "Weight increased": 6.697973130156867, "Wrong technique in product usage process": 2.527997699987852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/342.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/342.json
index ec09e3a37d0..62cf3968b7d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/342.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/342.json
@@ -1 +1 @@
-{"Anaphylactic shock ": 11.185645503700629, "Bradycardia ": 62.28228441829533, "Cardiac arrest ": 29.16191884508936, "Cardio-respiratory arrest ": 12.93173515765512, "Delirium ": 8.969880033973977, "Drug interaction ": 2.454379115203677, "Extravasation ": 90.8609320988482, "Generalised tonic-clonic seizure ": 9.923100689383936, "Hyperthermia ": 67.87160182829832, "Hypotension ": 6.4042122801462495, "Myoclonus ": 34.91096421203645, "Postoperative delirium ": 14791.92902198019, "Product administered to patient of inappropriate age ": 90.26655160878968, "Product use in unapproved indication ": 2.126510349780905, "Respiratory arrest ": 15.698888846479743, "Withdrawal syndrome ": 16.982351414976133}
\ No newline at end of file
+{"Abnormal weight gain": 44.96482191199119, "Aggression": 2.2133642558313658, "Aphonia": 11.179078206059978, "Asthma": 5.409335148203829, "Depressed mood": 2.7432208911221894, "Dermatitis exfoliative generalised": 7.623199009910531, "Disturbance in attention": 2.0283881500139285, "Drug hypersensitivity": 2.946506145206897, "Drug reaction with eosinophilia and systemic symptoms": 2.3656906914215536, "Dry mouth": 2.15119287518281, "Electrocardiogram QT prolonged": 2.6230803387564854, "Eosinophilia": 3.844574625483778, "Face oedema": 2.386858346690652, "Full blood count abnormal": 8.439381944953862, "Generalised tonic-clonic seizure": 2.5828653294725097, "Hepatic cytolysis": 2.5158029448369725, "Incorrect dose administered": 3.005280615616549, "Increased appetite": 8.575065830098017, "Intentional overdose": 4.923887587801009, "Intentional self-injury": 8.434215511454896, "Lip swelling": 2.0016277528159945, "Loss of personal independence in daily activities": 6.004930061983674, "Multiple organ dysfunction syndrome": 2.172706433892237, "Neuralgia": 2.360310786046996, "Nightmare": 2.6705397704222027, "Oedema": 2.050463468575645, "Overdose": 2.921857486838308, "Palpitations": 2.125269300558198, "Pancoast's syndrome": 4182.342890189411, "Papule": 6.877681052032816, "Paraesthesia oral": 2.014524297634052, "Petit mal epilepsy": 18.491660505131037, "Photosensitivity reaction": 5.9867980874682, "Product prescribing error": 6.887527920789664, "Product substitution issue": 6.438806872786277, "Product use in unapproved indication": 2.088007455306219, "Product use issue": 2.900080254614198, "Productive cough": 7.694851592706317, "Pruritus": 2.277475333328717, "Rash maculo-papular": 2.8120161366622383, "Rash pruritic": 2.1994532012948205, "Sleep apnoea syndrome": 8.04014145383151, "Sleep disorder due to a general medical condition": 23.36322839179094, "Somnolence": 3.307694783486563, "Speech disorder": 3.6926575066760736, "Swelling face": 2.000409859292987, "Swollen tongue": 2.7625054080265263, "Tachycardia": 2.0903260962010592, "Therapeutic product effect incomplete": 8.12869851958033, "Therapeutic response unexpected": 6.18754248686704, "Upper respiratory tract infection": 3.449905412019484, "Urticaria": 3.219566441839299, "Weight increased": 3.240443628515908, "Wheezing": 9.891707738466442, "Wrong product administered": 5.331284447257246}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/343.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/343.json
index 3cfa940db21..a560b59b78c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/343.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/343.json
@@ -1 +1 @@
-{"Agitation ": 9.927963903453598, "Anaphylactic shock ": 2.6236905544891456, "Blood pressure decreased ": 2.493666376935629, "Bradycardia ": 21.72925237247872, "Cardiac arrest ": 14.205922206338156, "Catatonia ": 50.98857888655453, "Delirium ": 22.479984511656056, "Drug interaction ": 2.956339243484857, "Drug withdrawal syndrome ": 5.25714211792707, "Drug withdrawal syndrome neonatal ": 20.131236801456076, "Dyskinesia ": 10.141396308326074, "Electrocardiogram QT prolonged ": 3.3765495905314906, "Electrolyte imbalance ": 19.769814507836617, "Exposure during pregnancy ": 2.8357807714388543, "Foetal exposure during pregnancy ": 13.070754128487645, "Haemodynamic instability ": 32.19564129964526, "Heart rate decreased ": 5.665609169208732, "Hyperthermia ": 11.327580015104171, "Hyperthermia malignant ": 106.40464124789246, "Hypotension ": 7.160703665576461, "Hypotonia ": 8.258811560657222, "Hypoxia ": 7.118176340894656, "Incorrect dose administered ": 3.450575076430014, "Intentional product use issue ": 4.518448539481129, "Laryngomalacia ": 799.1178864668753, "Maternal exposure during pregnancy ": 4.39142746434673, "Multiple organ dysfunction syndrome ": 8.805195481335653, "Myoclonus ": 11.69048483037068, "Neuroleptic malignant syndrome ": 6.936658181368837, "Overdose ": 2.1573167509016526, "Oxygen saturation decreased ": 4.111406849262989, "Poor feeding infant ": 80.6401665042981, "Porphyria acute ": 273.6694587616796, "Potentiating drug interaction ": 34.47845662404311, "Premature baby ": 17.384291923192563, "Premature delivery ": 22.995042803899363, "Product administered to patient of inappropriate age ": 72.59612084088424, "Product use in unapproved indication ": 3.463593450042466, "Respiratory depression ": 28.73982369144186, "Respiratory failure ": 9.175080296591018, "Restlessness ": 2.887949145125689, "Septic shock ": 5.164063319775541, "Sinus tachycardia ": 10.079415217941746, "Small for dates baby ": 76.56535589985788, "Tachycardia ": 2.8067732548361444, "Tachypnoea ": 18.70953887988479, "Therapeutic product effect incomplete ": 2.33233540626082, "Toxicity to various agents ": 2.264310416950857, "Upper airway obstruction ": 240.49301258016715, "Withdrawal syndrome ": 15.243475168220606}
\ No newline at end of file
+{"Hyperglycaemia": 59.36372930017131, "Hypoglycaemia": 21.92432809857477}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/344.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/344.json
index e04327cbcd8..1031975f4b2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/344.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/344.json
@@ -1 +1 @@
-{"Decreased appetite ": 4.379024180915872, "Febrile neutropenia ": 17.89241831710447, "Hepatic function abnormal ": 15.457328056668027, "Leukopenia ": 11.870806265102384, "Myelosuppression ": 179.84077526992706, "Neutrophil count decreased ": 20.877303544375746, "Platelet count decreased ": 8.024006433003622, "White blood cell count decreased ": 19.313771244146363}
\ No newline at end of file
+{"Abdominal abscess": 4.124563114499276, "Acute generalised exanthematous pustulosis": 2.7201427815545425, "Acute graft versus host disease": 4.022369304035951, "Acute leukaemia": 3.616592444754619, "Acute lymphocytic leukaemia": 6.211223301689223, "Acute lymphocytic leukaemia recurrent": 8.809030256787274, "Acute myeloid leukaemia": 3.9709771811867136, "Acute pulmonary oedema": 2.8638010818411157, "Acute respiratory distress syndrome": 2.9738023680935077, "Acute respiratory failure": 3.331387310564768, "Adenoviral hepatitis": 33.79675965304617, "Adenovirus infection": 4.152352555391031, "Adrenal insufficiency": 2.760800826596552, "Adult T-cell lymphoma/leukaemia": 21.510906939556435, "Allergy test negative": 64.21372087421484, "Amyloidosis": 7.687354726152503, "Anaphylactic reaction": 2.76206449194422, "Anaphylactic shock": 3.603413232380194, "Anaphylactoid shock": 10.871905814482997, "Antinuclear antibody positive": 2.809112172781676, "Apgar score low": 3.3869188274576723, "Aspergillus infection": 10.386760328861705, "Atelectasis": 5.003803583179847, "B-cell lymphoma recurrent": 35.471914707345675, "Bacteraemia": 3.909134349619796, "Bacterial infection": 2.778372302565254, "Bacterial sepsis": 4.262834122096557, "Biliary colic": 3.9249131775460726, "Blood disorder": 3.120193142015659, "Blood fibrinogen decreased": 5.643739498963088, "Blood gases abnormal": 27.04724523767948, "Blood immunoglobulin G increased": 5.404743698624089, "Blood lactate dehydrogenase increased": 2.8880169913793625, "Blood lactic acid increased": 5.0677640578044105, "Bone lesion": 7.526358970382487, "Bone marrow failure": 2.5426234393576865, "Bradycardia foetal": 4.239547821193649, "Brain abscess": 7.204712308273496, "Brain herniation": 2.925831862630325, "Brain oedema": 5.052341814905205, "Breech presentation": 9.188598959031625, "Bronchial wall thickening": 12.021268484245391, "Bronchopulmonary aspergillosis": 12.290064620483044, "Bronchospasm": 3.018925606549045, "COVID-19 pneumonia": 4.706866553598397, "CSF oligoclonal band present": 62.1567549657021, "Candida infection": 4.096932746649087, "Cardiac dysfunction": 3.481771537068132, "Cardiac failure": 2.1430425187191045, "Cardio-respiratory arrest": 2.2299250913318, "Cardiomegaly": 2.0022235605852496, "Cardiotoxicity": 4.370467078995968, "Cardiovascular insufficiency": 8.857730045138805, "Cataract subcapsular": 15.34273805360477, "Cell marker increased": 63.39164132231778, "Cell-mediated cytotoxicity": 259.1929187695648, "Cellulitis": 2.519189462948823, "Central nervous system lesion": 5.155574870203503, "Central nervous system vasculitis": 7.53853412402397, "Chronic graft versus host disease": 2.186108153613274, "Chronic lymphocytic leukaemia recurrent": 11.545341091342928, "Clonic convulsion": 3.636610799593918, "Clostridium difficile colitis": 4.550127804635343, "Clostridium test positive": 3.274504147349349, "Coma scale abnormal": 3.1092100583490416, "Computerised tomogram thorax abnormal": 19.353507199271213, "Corneal disorder": 8.726744751753595, "Corneal infiltrates": 17.6597211971491, "Corneal oedema": 6.258019797951771, "Corneal perforation": 13.420941394086444, "Cryptococcosis": 17.664675414895513, "Cushing's syndrome": 2.301918980296583, "Cystitis haemorrhagic": 2.571025902191264, "Cytokine release syndrome": 3.647737899475375, "Cytomegalovirus chorioretinitis": 13.3774686180267, "Cytomegalovirus infection": 3.5685349450646124, "Cytomegalovirus infection reactivation": 4.997893873827275, "Cytopenia": 9.800416036175008, "Deafness bilateral": 3.0112823143152725, "Deep vein thrombosis": 2.0609349777334045, "Diabetes insipidus": 2.220574815097564, "Diastolic dysfunction": 2.588943072809048, "Differentiation syndrome": 12.326770421750057, "Diffuse large B-cell lymphoma": 12.249817780774288, "Diffuse large B-cell lymphoma recurrent": 25.35581415392435, "Diffuse large B-cell lymphoma refractory": 26.661096797454302, "Disease progression": 6.346514982631191, "Disease recurrence": 2.57190255111258, "Disseminated cryptococcosis": 22.29877315067439, "Disseminated tuberculosis": 7.833025007002868, "Drug clearance decreased": 12.751456599435016, "Drug ineffective for unapproved indication": 3.816896028416704, "Drug resistance": 2.8762231290013283, "Ecthyma": 22.86960049905417, "Embolic stroke": 2.022854499494132, "Embolism": 3.733981138126457, "Encephalitis": 2.533197361953512, "Encephalopathy": 2.0026987228212128, "Endophthalmitis": 6.634141003208802, "Engraftment syndrome": 54.041685561337545, "Enterococcal infection": 5.625619747362891, "Enterocolitis": 3.915015587441159, "Eosinophil count abnormal": 10.004408132091012, "Epstein-Barr virus infection": 2.243267525166845, "Escherichia bacteraemia": 5.549743119403686, "Escherichia infection": 3.1092100583490416, "Escherichia sepsis": 13.373417124400287, "Exophthalmos": 3.1524336234019006, "Exposure during pregnancy": 2.1533724873572786, "Faeces soft": 2.2098825166835034, "Failure to thrive": 2.9292348358544604, "Febrile bone marrow aplasia": 7.264320089277079, "Febrile neutropenia": 11.222189385718016, "Foetal distress syndrome": 5.37767523036257, "Foetal exposure during pregnancy": 3.670418260284831, "Foetal growth restriction": 6.864727161145653, "Foetal hypokinesia": 7.523650426104128, "Follicular lymphoma": 15.566931912359967, "Food poisoning": 3.970088953212458, "Full blood count abnormal": 2.0017129261253546, "Full blood count decreased": 4.758344184158699, "Fusarium infection": 11.56229469541203, "Gastrointestinal inflammation": 5.3076534373207815, "Gastrointestinal necrosis": 4.008444039687495, "Gastrointestinal perforation": 2.210527748430587, "Gene mutation": 10.444869816058512, "Haematotoxicity": 4.171035044974905, "Haemodynamic instability": 4.515529056009427, "Haemophagocytic lymphohistiocytosis": 6.621375900074577, "Haemorrhoidal haemorrhage": 2.0055001369481844, "Hepatic cytolysis": 2.451016698001405, "Hepatic mass": 3.681153104708956, "Hepatitis B 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senile": 22.53477599001124, "Quadriplegia": 4.809409898683318, "Resorption bone increased": 30.33998188847294, "Respiratory acidosis": 3.051617448480653, "Respiratory failure": 3.376135757349134, "Reye's syndrome": 41.50299562260962, "Second primary malignancy": 2.055241307447792, "Sense of oppression": 2.1585048070201607, "Sepsis": 4.532554905915527, "Septic shock": 5.603984655104132, "Shock": 2.446297975352284, "Skin abrasion": 3.369096706702376, "Skin lesion": 2.0859224927568087, "Skin mass": 2.872356431873686, "Sleep disorder due to a general medical condition": 2.0451521204739187, "Soft tissue necrosis": 10.931447528419207, "Spina bifida": 2.5822555299887577, "Staphylococcal bacteraemia": 5.928865913947907, "Staphylococcal infection": 2.4028414597981507, "Staphylococcal sepsis": 2.2051839850569794, "Status epilepticus": 3.2836963107891437, "Steroid diabetes": 7.575629678333313, "Streptococcal infection": 3.1925055192795573, "Stridor": 3.2491920747160057, "Strongyloidiasis": 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virus infection": 3.2690655975285146, "Vestibular disorder": 3.2386727337666903, "Visual acuity reduced": 2.289041602109572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/345.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/345.json
index d2c6ba44035..799a4887e16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/345.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/345.json
@@ -1 +1 @@
-{"Decreased appetite ": 4.593587722755362, "Drug interaction ": 14.210294604701632, "Epilepsy ": 14.508609668481167, "Product use in unapproved indication ": 18.75878662027309, "Seizure ": 7.189511946676789, "Somnolence ": 6.659640569433}
\ No newline at end of file
+{"Anaphylactic shock": 11.185645503700629, "Bradycardia": 62.28032801078921, "Cardiac arrest": 29.16191884508936, "Cardio-respiratory arrest": 12.93173515765512, "Delirium": 8.969880033973977, "Drug interaction": 2.454379115203677, "Extravasation": 90.8609320988482, "Generalised tonic-clonic seizure": 9.923100689383936, "Hyperthermia": 67.87160182829832, "Hypotension": 6.40406421022552, "Myoclonus": 34.91096421203645, "Postoperative delirium": 14791.92902198019, "Product administered to patient of inappropriate age": 90.26655160878968, "Product use in unapproved indication": 2.1264440425342745, "Respiratory arrest": 15.698888846479743, "Withdrawal syndrome": 16.982351414976133}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/346.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/346.json
index 5162fc4c15a..05107a0e175 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/346.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/346.json
@@ -1 +1 @@
-{"Acute generalised exanthematous pustulosis ": 21.42782478114413, "Agranulocytosis ": 7.199926436183636, "Clostridium difficile colitis ": 189.13680161789384, "Clostridium difficile infection ": 312.5575424723945, "Condition aggravated ": 2.6499595569985366, "Death ": 2.236498412976659, "Dehydration ": 2.440967667630874, "Diarrhoea ": 3.45934891436333, "Disease recurrence ": 21.825328638329424, "Drug ineffective ": 5.318086026644783, "Eosinophilia ": 20.724558211876207, "General physical health deterioration ": 2.6584208792544746, "Hepatic cytolysis ": 7.859223317313034, "Hepatic enzyme increased ": 2.2150416323204, "Multiple organ dysfunction syndrome ": 4.835982362881562, "Off label use ": 2.2192719956832554, "Pancytopenia ": 5.893151436169882, "Product use issue ": 3.005565686521214, "Pseudomembranous colitis ": 47.81509754634903, "Rash erythematous ": 3.358881854448865, "Rash maculo-papular ": 8.011337854444514, "Rectal haemorrhage ": 4.142357476857005, "Treatment failure ": 11.770362438284357, "White blood cell count increased ": 10.662089775455318, "Wrong technique in product usage process ": 8.015360503660864}
\ No newline at end of file
+{"Agitation": 9.927963903453598, "Anaphylactic shock": 2.6236905544891456, "Blood pressure decreased": 2.4935854493243768, "Bradycardia": 21.7285700309672, "Cardiac arrest": 14.205922206338156, "Catatonia": 50.98857888655453, "Delirium": 22.479984511656056, "Drug interaction": 2.956339243484857, "Drug withdrawal syndrome": 5.25714211792707, "Drug withdrawal syndrome neonatal": 20.131236801456076, "Dyskinesia": 10.141396308326074, "Electrocardiogram QT prolonged": 3.3765495905314906, "Electrolyte imbalance": 19.769814507836617, "Exposure during pregnancy": 2.8357807714388543, "Foetal exposure during pregnancy": 13.070754128487645, "Haemodynamic instability": 32.19564129964526, "Heart rate decreased": 5.665609169208732, "Hyperthermia": 11.327580015104171, "Hyperthermia malignant": 106.40464124789246, "Hypotension": 7.160538024867172, "Hypotonia": 8.25792394985899, "Hypoxia": 7.118176340894656, "Incorrect dose administered": 3.450575076430014, "Intentional product use issue": 4.518448539481129, "Laryngomalacia": 799.1178864668753, "Maternal exposure during pregnancy": 4.39142746434673, "Multiple organ dysfunction syndrome": 8.805195481335653, "Myoclonus": 11.69048483037068, "Neuroleptic malignant syndrome": 6.936658181368837, "Overdose": 2.1573167509016526, "Oxygen saturation decreased": 4.111186864909145, "Poor feeding infant": 80.6401665042981, "Porphyria acute": 273.6694587616796, "Potentiating drug interaction": 34.47845662404311, "Premature baby": 17.384291923192563, "Premature delivery": 22.995042803899363, "Product administered to patient of inappropriate age": 72.59612084088424, "Product use in unapproved indication": 3.4634854195071494, "Respiratory depression": 28.73982369144186, "Respiratory failure": 9.174322260056558, "Restlessness": 2.887796844041424, "Septic shock": 5.164063319775541, "Sinus tachycardia": 10.079415217941746, "Small for dates baby": 76.56535589985788, "Tachycardia": 2.806702311773104, "Tachypnoea": 18.70687499240957, "Therapeutic product effect incomplete": 2.33233540626082, "Toxicity to various agents": 2.264310416950857, "Upper airway obstruction": 240.49301258016715, "Withdrawal syndrome": 15.243475168220606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/347.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/347.json
index c124c35d0c0..c8b222264ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/347.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/347.json
@@ -1 +1 @@
-{"Dyspepsia ": 15.696342255804302}
\ No newline at end of file
+{"Decreased appetite": 4.3789817077056, "Febrile neutropenia": 17.89241831710447, "Hepatic function abnormal": 15.457328056668027, "Leukopenia": 11.869310003715464, "Myelosuppression": 179.84077526992706, "Neutrophil count decreased": 20.877303544375746, "Platelet count decreased": 8.024006433003622, "White blood cell count decreased": 19.313771244146363}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/348.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/348.json
index a04650395a7..ecb27214d87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/348.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/348.json
@@ -1 +1 @@
-{"Capillary leak syndrome ": 325.70387410689574, "Constipation ": 3.231003234348296, "Cough ": 3.441303630246199, "Hypertension ": 2.238422995590371, "Neoplasm progression ": 20.642783159820247, "Neuralgia ": 14.104996693691866, "Neuropathy peripheral ": 8.55264294995484, "Off label use ": 4.895620121099849, "Pain ": 2.0656398630683253, "Pneumonia ": 3.986074434719807, "Post transplant lymphoproliferative disorder ": 95.8295562186226, "Product use in unapproved indication ": 5.083493182447235, "Product use issue ": 8.80475975568574, "Respiratory distress ": 35.678279929193934, "Thrombocytopenia ": 2.6304561803338857, "Thrombotic microangiopathy ": 63.43992733938562, "Wheezing ": 10.335886914533916}
\ No newline at end of file
+{"Decreased appetite": 4.593543168818944, "Drug interaction": 14.210294604701632, "Epilepsy": 14.508609668481167, "Product use in unapproved indication": 18.758201537734205, "Seizure": 7.188714982613595, "Somnolence": 6.659567161602454}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/349.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/349.json
index b8c2965e9e8..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/349.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/349.json
@@ -1 +1 @@
-{"Toxicity to various agents ": 35.05229652468624}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/35.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/35.json
index 56cd1b8a431..447708f8db2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/35.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/35.json
@@ -1 +1 @@
-{"5-hydroxyindolacetic acid ": 499.4579594245425, "Abdominal hernia ": 4.5474259602847695, "Abdominal lymphadenopathy ": 9.759370540798306, "Abdominal mass ": 6.468663761623113, "Acne ": 3.125891664429479, "Alveolitis ": 3.1906543612341203, "Anaemia ": 2.1570735096351243, "Aphthous ulcer ": 10.51274848222767, "Ascites ": 5.301498375640612, "Atelectasis ": 4.082852631121483, "Atypical pneumonia ": 6.171036234868677, "Biliary obstruction ": 3.2376706260655514, "Blood albumin decreased ": 3.462448718389714, "Blood bilirubin abnormal ": 7.802715664683691, "Blood calcium increased ": 2.3403314432368343, "Blood cholesterol increased ": 2.512657951130949, "Blood chromogranin A increased ": 51.08027883029757, "Blood creatinine decreased ": 2.568708812284544, "Blood creatinine increased ": 2.77306004088811, "Blood lactate dehydrogenase increased ": 3.536346838385686, "Blood magnesium decreased ": 2.228789683783329, "Blood phosphorus decreased ": 2.5728424348296017, "Blood potassium decreased ": 2.1305310899788896, "Blood pressure diastolic decreased ": 9.092616237261607, "Blood pressure diastolic increased ": 2.499541575222969, "Blood pressure increased ": 2.0400831043519703, "Blood pressure systolic increased ": 9.611864717547988, "Blood triglycerides increased ": 5.776707406822929, "Blood urine present ": 2.5053126709686, "Body temperature decreased ": 6.274821373163245, "Bone cancer ": 6.003434854442488, "Bone lesion ": 9.948441682015956, "Bowel movement irregularity ": 3.9177210908273854, "Brain neoplasm ": 4.15923941283406, "Breast cancer ": 7.69211205303828, "Breast cancer female ": 4.0395693042904295, "Breast cancer metastatic ": 30.027715219178152, "Breast cancer recurrent ": 45.78169764025509, "Breast cancer stage II ": 2.5560390220774245, "Breast cancer stage IV ": 20.87903442957103, "Bundle branch block left ": 2.113348141775294, "Cachexia ": 4.862888257165355, "Cancer pain ": 6.824567845854038, "Carbohydrate antigen 15-3 increased ": 33.69136190591275, "Carcinoembryonic antigen increased ": 9.251810685309112, "Carcinoid syndrome ": 35.26338707495082, "Carcinoid tumour ": 25.124995252613115, "Carcinoid tumour pulmonary ": 124.10684493735268, "Cellulitis ": 2.1386922874364607, "Central nervous system lesion ": 2.4324825114246997, "Chapped lips ": 2.939501014896292, "Cholangitis ": 3.3657958534526253, "Clear cell renal cell carcinoma ": 10.43651603177777, "Coccydynia ": 5.593357305773886, "Concomitant disease aggravated ": 7.396489726408137, "Concomitant disease progression ": 9.22591754807395, "Cough ": 3.4703943817435525, "Crepitations ": 9.87161685521753, "Death ": 3.1521652151322668, "Decreased appetite ": 2.292394012593065, "Dehydration ": 2.5633147801284784, "Dermatitis acneiform ": 2.122595009066924, "Diabetes mellitus ": 4.081175119782228, "Disease progression ": 2.9406368613263028, "Dry skin ": 3.817373380609828, "Dyslipidaemia ": 2.0256709571599485, "Eating disorder ": 3.711984735048484, "Ejection fraction decreased ": 3.0706982150428592, "Epistaxis ": 2.656562792161421, "Exposed bone in jaw ": 42.05720486695459, "Eyelid oedema ": 2.2329637381596434, "Faeces discoloured ": 2.1523963114399183, "Feeding disorder ": 5.230621270443996, "Flatulence ": 2.0057526816575786, "Fractured sacrum ": 9.769904617971568, "Frequent bowel movements ": 2.0952357970050968, "Gallbladder disorder ": 2.0746916290197914, "General physical health deterioration ": 2.468976506471777, "Generalised oedema ": 2.8778620779073507, "Gingival swelling ": 2.7058668508747967, "Gingivitis ": 2.7370410412370303, "Glomerular filtration rate decreased ": 2.012363621273318, "Glucose tolerance impaired ": 3.191880854662179, "Haematocrit decreased ": 2.985292321842172, "Haemoglobin decreased ": 2.86928839708625, "Hepatic lesion ": 19.424493777696824, "Hepatic mass ": 9.544977231954917, "Hepatic neoplasm ": 10.010872653601751, "Hepatic pain ": 2.6467467875753243, "Hydronephrosis ": 2.355897066629236, "Hypercholesterolaemia ": 4.382970083063183, "Hyperglycaemia ": 5.648373004664907, "Hyperlipidaemia ": 4.740089003813893, "Hypertriglyceridaemia ": 6.691169263402753, "Hypophagia ": 3.2685191469359127, "Hypophosphataemia ": 2.031309109486191, "Hypoxia ": 2.075621553182282, "Ingrowing nail ": 17.27073874395147, "Injection site hypersensitivity ": 4.325629874317341, "Injection site mass ": 2.7466937902185693, "Interstitial lung disease ": 18.38645350175561, "Intestinal metastasis ": 18.58988144173605, "Intestinal obstruction ": 3.31715443991416, "Invasive ductal breast carcinoma ": 3.507314396638059, "Iron deficiency anaemia ": 2.321564740074885, "Jugular vein thrombosis ": 3.082204146471866, "KL-6 increased ": 49.38753817057257, "Lip ulceration ": 4.308765376520227, "Liver abscess ": 2.9437723717783646, "Liver function test increased ": 2.051059716885652, "Lung consolidation ": 4.913301794652878, "Lung disorder ": 4.942857754399042, "Lung infiltration ": 8.936308768339808, "Lung neoplasm ": 6.287154585902235, "Lung opacity ": 6.294669682747965, "Lymphadenopathy mediastinal ": 6.464462867837981, "Lymphangiosis carcinomatosa ": 35.32766317841092, "Lymphocyte count decreased ": 4.704634047013764, "Lymphocyte count increased ": 2.8116550337994286, "Lymphoedema ": 3.349879022962376, "Malignant ascites ": 10.65652931067766, "Malignant neoplasm progression ": 28.992812975770253, "Malignant pleural effusion ": 14.9870654855149, "Mass ": 2.679310747889804, "Metastases to adrenals ": 16.67909751977598, "Metastases to bone ": 29.473717364568763, "Metastases to central nervous system ": 16.832961994307073, "Metastases to chest wall ": 48.23251351460835, "Metastases to kidney ": 23.88215817212511, "Metastases to liver ": 37.86328708578322, "Metastases to lung ": 23.47041266434797, "Metastases to lymph nodes ": 14.897583730474066, "Metastases to meninges ": 4.5901097025415, "Metastases to pancreas ": 17.951142535889385, "Metastases to peritoneum ": 16.39410410068564, "Metastases to pleura ": 19.00742993054101, "Metastases to skin ": 21.59419135596566, "Metastases to spine ": 22.782134037202567, "Metastases to the mediastinum ": 24.129649230925665, "Metastasis ": 15.476127537598192, "Metastatic renal cell carcinoma ": 10.201155270081228, "Mouth ulceration ": 7.061031308176213, "Mucosal inflammation ": 17.805555917671324, "Musculoskeletal pain ": 2.061481348245846, "Nail disorder ": 5.515484474578983, "Nasal discharge discolouration ": 17.186241379549326, "Necrosis ": 2.6043610037800784, "Needle issue ": 6.743415216481868, "Neoplasm ": 2.6849896087158025, "Neoplasm progression ": 14.766692290719275, "Neoplasm recurrence ": 2.851068581942908, "Nephritic syndrome ": 52.05237856534719, "Neuroendocrine tumour ": 170.68746585727607, "Neuroendocrine tumour of the lung ": 117.59567765322556, "Neuroendocrine tumour of the rectum ": 224.0023327940353, "Oedema ": 2.3228574040088965, "Oedema peripheral ": 3.292260042409957, "Oncologic complication ": 21.26754160233977, "Onychoclasis ": 6.931663734707629, "Oral pain ": 5.999807247439297, "Organising pneumonia ": 2.239683745433949, "Orthopnoea ": 2.8104044762110227, "Osteonecrosis of jaw ": 13.30002107270266, "Ovarian cyst ": 2.738394351629312, "PIK3CA-activated mutation ": 39.19263695492248, "Palmar-plantar erythrodysaesthesia syndrome ": 2.9568123020456776, "Pancreatic neuroendocrine tumour ": 175.0589038120881, "Pancreatic neuroendocrine tumour metastatic ": 97.65212229684352, "Paronychia ": 5.100274896045671, "Pathological fracture ": 2.224091513190162, "Pericardial effusion ": 2.94644895546623, "Platelet count decreased ": 3.4092589138839258, "Platelet count increased ": 2.567058554965121, "Pleural effusion ": 5.85024531693692, "Pleural thickening ": 6.412706273956337, "Pneumocystis jirovecii pneumonia ": 6.639894025005895, "Pneumonia ": 2.4807119872560977, "Pneumonia bacterial ": 2.5478311057672065, "Pneumonitis ": 32.928356301331306, "Productive cough ": 2.580564808163351, "Protein total decreased ": 6.586807731232621, "Pulmonary mass ": 5.010748721030412, "Pulmonary toxicity ": 4.731246349273605, "Rales ": 2.577635253962545, "Recurrent cancer ": 6.722774516237736, "Red blood cell count decreased ": 2.3739848693195924, "Red cell distribution width increased ": 6.215943004040406, "Renal cancer ": 5.492986033279347, "Renal cancer metastatic ": 4.804312805757988, "Renal cell carcinoma ": 9.650104782768585, "Renal function test abnormal ": 2.125804950082524, "Renal mass ": 5.28680995128321, "Respiratory rate increased ": 3.131303588930069, "Second primary malignancy ": 8.531782974896268, "Skin toxicity ": 2.6620528436674338, "Small intestinal haemorrhage ": 3.5317128497867434, "Small intestine neuroendocrine tumour ": 113.71806631872823, "Spinal compression fracture ": 2.363545785844253, "Spinal cord compression ": 2.34167965248125, "Splenic lesion ": 20.32572320793658, "Steatorrhoea ": 10.769297673432783, "Stomatitis ": 30.129564049329097, "Taste disorder ": 2.7495831874741232, "Terminal state ": 2.592940712326932, "Tongue oedema ": 2.0283300029211078, "Tongue ulceration ": 3.8310760341552657, "Tooth abscess ": 2.502713380858896, "Tumour haemorrhage ": 2.132898641627506, "Tumour marker increased ": 20.60607414766788, "Tumour necrosis ": 8.066318615528973, "Ulcer ": 2.53925596295972, "Urine output decreased ": 3.647395721832288, "Urosepsis ": 3.124500738931743, "Weight decreased ": 2.5558923235153173}
\ No newline at end of file
+{"Diarrhoea": 4.689944611168707, "Disease progression": 23.84815653129202, "Drug resistance": 46.1857950846204, "Malignant neoplasm progression": 10.974094265330796, "Metastases to central nervous system": 54.04114445315533, "Paronychia": 245.1656015327333}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/350.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/350.json
index 52761310c6d..c636defd7cc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/350.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/350.json
@@ -1 +1 @@
-{"Pallor ": 89.76635320086456}
\ No newline at end of file
+{"Acute generalised exanthematous pustulosis": 21.42782478114413, "Agranulocytosis": 7.199926436183636, "Clostridium difficile colitis": 189.13680161789384, "Clostridium difficile infection": 312.5575424723945, "Condition aggravated": 2.6499595569985366, "Death": 2.236498412976659, "Dehydration": 2.440837386820719, "Diarrhoea": 3.4593200395074857, "Disease recurrence": 21.825328638329424, "Drug ineffective": 5.3180467013505, "Eosinophilia": 20.724558211876207, "General physical health deterioration": 2.6584208792544746, "Hepatic cytolysis": 7.859223317313034, "Hepatic enzyme increased": 2.2150416323204, "Multiple organ dysfunction syndrome": 4.835982362881562, "Off label use": 2.219184580618189, "Pancytopenia": 5.893151436169882, "Product use issue": 3.005565686521214, "Pseudomembranous colitis": 47.81509754634903, "Rash erythematous": 3.358881854448865, "Rash maculo-papular": 8.011337854444514, "Rectal haemorrhage": 4.142357476857005, "Treatment failure": 11.770362438284357, "White blood cell count increased": 10.66004736241396, "Wrong technique in product usage process": 8.015360503660864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/351.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/351.json
index 5af9ad9b350..1af7af33889 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/351.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/351.json
@@ -1 +1 @@
-{"Erythema ": 14.271117903643184}
\ No newline at end of file
+{"Dyspepsia": 15.696342255804302}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/352.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/352.json
index 65af8195b64..4c36b4ccd19 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/352.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/352.json
@@ -1 +1 @@
-{"Completed suicide ": 12.884982657373282, "Toxicity to various agents ": 8.95414886981355}
\ No newline at end of file
+{"Capillary leak syndrome": 325.70387410689574, "Constipation": 3.231003234348296, "Cough": 3.4412717120725054, "Hypertension": 2.238399889183431, "Neoplasm progression": 20.642783159820247, "Neuralgia": 14.104996693691866, "Neuropathy peripheral": 8.552383298644084, "Off label use": 4.895427286254522, "Pain": 2.065622305342374, "Pneumonia": 3.986074434719807, "Post transplant lymphoproliferative disorder": 95.8295562186226, "Product use in unapproved indication": 5.083334655697058, "Product use issue": 8.80475975568574, "Respiratory distress": 35.678279929193934, "Thrombocytopenia": 2.6302087557534537, "Thrombotic microangiopathy": 63.43992733938562, "Wheezing": 10.3354758112876}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/353.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/353.json
index 276225fdba2..40af2c6142e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/353.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/353.json
@@ -1 +1 @@
-{"Abdominal rigidity ": 5.028909578183704, "Acute myeloid leukaemia ": 8.819056743230345, "Acute promyelocytic leukaemia ": 10.784139793103844, "Acute respiratory distress syndrome ": 2.416084371920168, "Adenocarcinoma ": 12.615312877641166, "Agranulocytosis ": 10.306756079425655, "Alopecia ": 4.859122999566714, "Alopecia areata ": 11.62397892148129, "Alopecia totalis ": 16.121330373829316, "Anaemia ": 2.565101398913, "Aortitis ": 15.012815887936876, "Bacteraemia ": 2.677746635246708, "Bicytopenia ": 24.46520389994795, "Bone lesion ": 7.0441261277357, "Bone marrow failure ": 2.0254688072065354, "Bone pain ": 2.480038351855703, "Breast cancer ": 2.2618099766331747, "Breast cancer female ": 3.406063262185252, "Breast cancer metastatic ": 14.60093476357107, "Breast cancer recurrent ": 22.72779337959479, "Breast mass ": 2.3004530437062853, "Cancer pain ": 5.909131265198146, "Candida sepsis ": 17.748759751848592, "Carbohydrate antigen 15-3 increased ": 13.523293254243129, "Carbon dioxide decreased ": 14.264037409162777, "Cardiac dysfunction ": 4.619821581877209, "Cardiac failure ": 2.7446753355863094, "Cardiomyopathy ": 3.411860153821106, "Cardiotoxicity ": 21.51273409866998, "Chemotherapy ": 12.074243086951403, "Chronic myeloid leukaemia ": 2.7165864046703736, "Cytopenia ": 6.39954381855615, "Dacryostenosis acquired ": 55.22500378149138, "Decreased appetite ": 2.685507713161344, "Device related infection ": 3.8409877748685113, "Diarrhoea ": 3.07888808697713, "Dilated cardiomyopathy ": 2.76831511211151, "Disease progression ": 8.22606082815974, "Disease recurrence ": 2.617103535320575, "Drug resistance ": 2.057671630307007, "Ejection fraction decreased ": 19.65662482842396, "Enteritis ": 8.507164252657601, "Enterocolitis ": 5.291246879271678, "Eosinophil count decreased ": 10.163486851016634, "Febrile neutropenia ": 28.6039918549468, "Gastrointestinal necrosis ": 5.149910107105815, "Gastrointestinal toxicity ": 8.475191946069234, "Granulocyte count decreased ": 29.809336165949333, "Granulocytopenia ": 16.80505747082617, "HER2 positive breast cancer ": 60.21118480566387, "Haematotoxicity ": 16.664863617161, "Hair colour changes ": 10.752739606272568, "Hair texture abnormal ": 19.602769801409373, "Hepatic function abnormal ": 3.646807882703908, "Hepatic lesion ": 4.084418921600537, "Hormone-refractory prostate cancer ": 31.42073171900225, "Hypoalbuminaemia ": 3.427118686237361, "Hypocalcaemia ": 2.87736709661984, "Hypomagnesaemia ": 2.303911105122637, "Ileus paralytic ": 6.388616230068829, "Interstitial lung disease ": 4.070969174074145, "Intestinal obstruction ": 2.5208705875980018, "Invasive ductal breast carcinoma ": 6.918153166044202, "Lacrimation increased ": 2.313130989077009, "Large intestine perforation ": 4.969710625873473, "Left ventricular dysfunction ": 12.845707313435303, "Leukoencephalopathy ": 4.176121464472854, "Leukopenia ": 8.147973514141079, "Lower limb fracture ": 2.213641969034443, "Lung adenocarcinoma ": 14.324400832077291, "Lymphocyte count decreased ": 4.095361731196704, "Lymphopenia ": 2.9178734386698912, "Madarosis ": 28.634906865586395, "Malignant neoplasm progression ": 6.961275829144909, "Mastectomy ": 9.743275516649092, "Metastases to bone ": 18.209331432456565, "Metastases to central nervous system ": 9.551172068634004, "Metastases to liver ": 13.095444590288958, "Metastases to lung ": 15.80763441352502, "Metastases to lymph nodes ": 19.01086616611968, "Metastases to peritoneum ": 4.365230794928159, "Metastases to pleura ": 12.567505471785957, "Metastases to skin ": 18.2761915385294, "Metastases to spine ": 4.508553353777948, "Metastases to the mediastinum ": 46.6027442241182, "Metastasis ": 21.238099804132546, "Mouth ulceration ": 2.1575535697871917, "Mucosal inflammation ": 11.1819402652812, "Myelodysplastic syndrome ": 4.9583661044732095, "Myelosuppression ": 48.89011241487291, "Nail disorder ": 14.73465580338538, "Nasal disorder ": 13.998010511142423, "Neoplasm progression ": 3.9210568211633503, "Neoplasm recurrence ": 16.70196546036002, "Neuropathy peripheral ": 4.935840458630976, "Neurotoxicity ": 4.2277405777198, "Neutropenia ": 8.784217499544068, "Neutropenic colitis ": 23.721687015940727, "Neutropenic sepsis ": 7.723748318635585, "Neutrophil count decreased ": 34.6332450366487, "Neutrophil count increased ": 3.8817215350565952, "Non-small cell lung cancer ": 17.51882348616584, "Oesophagitis ": 3.056369699064993, "Onycholysis ": 18.73956889653857, "Osteonecrosis of jaw ": 3.952831959644103, "Palmar-plantar erythrodysaesthesia syndrome ": 4.53870810103801, "Paronychia ": 5.435922286220248, "Peripheral sensory neuropathy ": 4.271454127678446, "Peritonitis ": 2.2139518672388983, "Platelet count decreased ": 2.002123354832943, "Pleural effusion ": 3.3059096040541758, "Pneumatosis intestinalis ": 5.056969776330204, "Pneumocystis jirovecii pneumonia ": 2.5702896223938048, "Pneumonitis ": 2.8653892941791006, "Polyneuropathy ": 8.982403123324195, "Portal venous gas ": 56.987472475308735, "Prostate cancer ": 3.896826834079503, "Prostate cancer metastatic ": 32.343223176880564, "Prostatic specific antigen increased ": 15.151697270019106, "Pulmonary mass ": 2.9186407385575883, "Red cell distribution width increased ": 7.111332685901453, "Second primary malignancy ": 7.366515751135224, "Septic shock ": 3.840512063938932, "Skin toxicity ": 10.582405339649268, "Stomatitis ": 4.552268820396817, "Subacute cutaneous lupus erythematosus ": 9.68083023843458, "Subclavian vein thrombosis ": 36.335822128779775, "Systemic scleroderma ": 38.2202431150985, "Therapy partial responder ": 7.711904578613736, "Tongue ulceration ": 6.127561723515743, "Tonsillar disorder ": 36.672353537887865, "Troponin I increased ": 9.02382135245436, "Tumour lysis syndrome ": 3.306028825119776, "Uterine leiomyoma ": 3.559454552087941, "Uterine leiomyosarcoma ": 92.3979135954961, "Vascular device infection ": 4.413321136500792, "White blood cell count decreased ": 23.808916684689176, "White blood cell count increased ": 2.0993060115055737}
\ No newline at end of file
+{"Toxicity to various agents": 35.05229652468624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/354.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/354.json
index 037a0eba647..f692eb93660 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/354.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/354.json
@@ -1 +1 @@
-{"Atrial fibrillation ": 16.851594821294245, "Drug interaction ": 6.6909984777142135, "Electrocardiogram QT prolonged ": 38.93381479128505}
\ No newline at end of file
+{"Pallor": 89.76067702034715}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/355.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/355.json
index 3263701565f..060e146dc98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/355.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/355.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 3.1330095999477057, "Aphasia ": 3.722706740607183, "Blood HIV RNA increased ": 161.48362298599707, "Condition aggravated ": 2.037388976246975, "Depressed level of consciousness ": 3.4339370663475286, "Drug interaction ": 2.4446326528610127, "Drug resistance ": 16.338730060176587, "Exposure during pregnancy ": 6.658141928916503, "Foetal exposure during pregnancy ": 6.160317009750506, "Foetal growth restriction ": 11.893823751249432, "Generalised tonic-clonic seizure ": 4.2633749946342725, "Gestational diabetes ": 33.81449259053695, "Hepatitis C ": 4.765148696447183, "Immune reconstitution inflammatory syndrome ": 203.1557820626649, "Immune reconstitution inflammatory syndrome associated tuberculosis ": 372.8722313325229, "Lactic acidosis ": 4.342632317561691, "Leukocytosis ": 6.986331431046132, "Live birth ": 10.904616724138082, "Liver injury ": 3.84765355622666, "Mental status changes ": 5.956877568247251, "Muscular weakness ": 2.306513241887995, "Nephropathy toxic ": 122.68740612527888, "Pancytopenia ": 2.3538100855586124, "Pathogen resistance ": 83.16547948207413, "Pericardial effusion ": 6.064657975868012, "Polyneuropathy ": 27.501523657553747, "Premature baby ": 5.612270060079436, "Progressive multifocal leukoencephalopathy ": 31.865709654787818, "Psychiatric symptom ": 29.68566372575558, "Renal disorder ": 3.6878288503511856, "Renal impairment ": 2.0599371832513715, "Renal tubular disorder ": 22.02158730724053, "Skin lesion ": 4.152409441463069, "Treatment noncompliance ": 28.696180028118555, "Viral load increased ": 25.150319199271856, "Viral mutation identified ": 183.7559197868926, "Virologic failure ": 213.4464445613229}
\ No newline at end of file
+{"Erythema": 14.27097833202684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/356.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/356.json
index 28c29d1e555..c2244064bc0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/356.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/356.json
@@ -1 +1 @@
-{"Chondrolysis ": 83876.61688034111, "Musculoskeletal pain ": 599.3138099904689}
\ No newline at end of file
+{"Completed suicide": 12.884982657373282, "Toxicity to various agents": 8.95414886981355}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/357.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/357.json
index 0093978d029..1484a528f30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/357.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/357.json
@@ -1 +1 @@
-{"Drug interaction ": 15.707486753813953, "Respiratory failure ": 15.2880695457815, "Sepsis ": 14.776321272538222}
\ No newline at end of file
+{"Abdominal rigidity": 5.0274011211432885, "Acute myeloid leukaemia": 8.81641094338189, "Acute promyelocytic leukaemia": 10.780904969572008, "Acute respiratory distress syndrome": 2.415359606715911, "Adenocarcinoma": 12.611528695925712, "Agranulocytosis": 10.3036632236459, "Alopecia": 4.85766469823197, "Alopecia areata": 11.620491977987236, "Alopecia totalis": 16.11649467259715, "Anaemia": 2.573123446414012, "Aortitis": 15.008312570377834, "Bacteraemia": 2.676943400840561, "Bicytopenia": 24.457864657019265, "Bone lesion": 7.042013162264041, "Bone marrow failure": 2.0248612367122547, "Bone pain": 2.479294309095321, "Breast cancer": 2.2611314101877427, "Breast cancer female": 3.4050415744625635, "Breast cancer metastatic": 14.596554217244952, "Breast cancer recurrent": 22.72097530100633, "Breast mass": 2.299763002844361, "Cancer pain": 5.907358770710211, "Candida sepsis": 17.743435841229733, "Carbohydrate antigen 15-3 increased": 13.519236850514938, "Carbon dioxide decreased": 14.259758772707125, "Cardiac dysfunction": 4.618435820008648, "Cardiac failure": 2.743600572402576, "Cardiomyopathy": 3.410836650269024, "Cardiotoxicity": 21.50628019338558, "Chemotherapy": 12.070621251638403, "Chronic myeloid leukaemia": 2.7157715451279856, "Cytopenia": 6.392497593129625, "Dacryostenosis acquired": 55.20843720460139, "Decreased appetite": 2.684675632532356, "Device related infection": 3.839835594120896, "Diarrhoea": 3.0779379361781616, "Dilated cardiomyopathy": 2.767484724194341, "Disease progression": 8.223591989799681, "Disease recurrence": 2.616318439607925, "Drug resistance": 2.057054354931867, "Ejection fraction decreased": 19.65072698574972, "Enteritis": 8.504612285310422, "Enterocolitis": 5.289659659040225, "Eosinophil count decreased": 10.160438199064352, "Febrile neutropenia": 28.629989018094147, "Gastrointestinal necrosis": 5.148365347366503, "Gastrointestinal toxicity": 8.472649627069885, "Granulocyte count decreased": 29.800393023951813, "Granulocytopenia": 16.79507584085875, "HER2 positive breast cancer": 60.193124052351465, "Haematotoxicity": 16.659864057754387, "Hair colour changes": 10.749513942419506, "Hair texture abnormal": 19.596889298428984, "Hepatic function abnormal": 3.6457136427803016, "Hepatic lesion": 4.083193753420265, "Hormone-refractory prostate cancer": 31.411306147416752, "Hypoalbuminaemia": 3.4260906695037123, "Hypocalcaemia": 2.876503960970272, "Hypomagnesaemia": 2.303220014465062, "Ileus paralytic": 6.386699811510123, "Interstitial lung disease": 4.069747627390993, "Intestinal obstruction": 2.520114377391215, "Invasive ductal breast carcinoma": 6.916077914407778, "Lacrimation increased": 2.3124370944806736, "Large intestine perforation": 4.96821987938351, "Left ventricular dysfunction": 12.841853667874345, "Leukoencephalopathy": 4.174868794844409, "Leukopenia": 8.144491404671667, "Lower limb fracture": 2.212977942913557, "Lung adenocarcinoma": 14.32010390380113, "Lymphocyte count decreased": 4.09413321701253, "Lymphopenia": 2.916998146469159, "Madarosis": 28.62631686126565, "Malignant neoplasm progression": 6.9591864826706935, "Mastectomy": 9.740352953705187, "Metastases to bone": 18.2038678386517, "Metastases to central nervous system": 9.548306702064526, "Metastases to liver": 13.09151542299708, "Metastases to lung": 15.802891653483467, "Metastases to lymph nodes": 19.005162707479982, "Metastases to peritoneum": 4.363921412940717, "Metastases to pleura": 12.563735743835828, "Metastases to skin": 18.27070930325796, "Metastases to spine": 4.507200981192674, "Metastases to the mediastinum": 46.5887650351626, "Metastasis": 21.231728302693725, "Mouth ulceration": 2.1569063492458667, "Mucosal inflammation": 11.178585162236107, "Myelodysplastic syndrome": 4.956878666132281, "Myelosuppression": 48.87542607231311, "Nail disorder": 14.730235569039053, "Nasal disorder": 13.993811534848758, "Neoplasm progression": 3.9198804299140657, "Neoplasm recurrence": 16.69695529630055, "Neuropathy peripheral": 4.93420867254042, "Neurotoxicity": 4.226472316353257, "Neutropenia": 8.793105132092522, "Neutropenic colitis": 23.714571167964287, "Neutropenic sepsis": 7.721431403401235, "Neutrophil count decreased": 34.62284664653982, "Neutrophil count increased": 3.8805571486384896, "Non-small cell lung cancer": 17.513567983371544, "Oesophagitis": 3.05545288688317, "Onycholysis": 18.733947733431304, "Osteonecrosis of jaw": 3.95164622060144, "Palmar-plantar erythrodysaesthesia syndrome": 4.537346373477682, "Paronychia": 5.434291712191003, "Peripheral sensory neuropathy": 4.2701728296195975, "Peritonitis": 2.213287758370078, "Platelet count decreased": 2.001522640333396, "Pleural effusion": 3.3046122868531937, "Pneumatosis intestinalis": 5.05545290243944, "Pneumocystis jirovecii pneumonia": 2.569518615565977, "Pneumonitis": 2.8645296967622027, "Polyneuropathy": 8.979708297874323, "Portal venous gas": 56.970378319483046, "Prostate cancer": 3.8956577990466297, "Prostate cancer metastatic": 32.33352066749576, "Prostatic specific antigen increased": 15.147151532881155, "Pulmonary mass": 2.9177652190086456, "Red cell distribution width increased": 7.109199533740688, "Second primary malignancy": 7.364305891823765, "Septic shock": 3.8393598819895898, "Skin toxicity": 10.563897447393977, "Stomatitis": 4.550902949148209, "Subacute cutaneous lupus erythematosus": 9.677926406363946, "Subclavian vein thrombosis": 36.32492223547745, "Systemic scleroderma": 38.20877824310973, "Therapy partial responder": 7.709591095369095, "Tongue ulceration": 6.125723691725801, "Tonsillar disorder": 36.66135298200761, "Troponin I increased": 8.995577780153678, "Tumour lysis syndrome": 3.305037123296783, "Uterine leiomyoma": 3.558386868311663, "Uterine leiomyosarcoma": 92.37019843880036, "Vascular device infection": 4.411997310390493, "White blood cell count decreased": 23.80176721955633, "White blood cell count increased": 2.098273468327702}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/358.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/358.json
index d3bca616224..47475637919 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/358.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/358.json
@@ -1 +1 @@
-{"Bronchial hyperreactivity ": 265.38219228543363, "Gait disturbance ": 2.645975776467828, "Product dose omission issue ": 5.932841394173069, "Suicidal ideation ": 4.502416794398693, "Weight increased ": 4.002128469983708, "Wheezing ": 6.495459550206273}
\ No newline at end of file
+{"Atrial fibrillation": 16.85113483507284, "Drug interaction": 6.6909984777142135, "Electrocardiogram QT prolonged": 38.93381479128505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/359.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/359.json
index 347b4f44544..9ef265180a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/359.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/359.json
@@ -1 +1 @@
-{"Acquired gene mutation ": 33.07876840221489, "Acute graft versus host disease ": 11.27876069501697, "Acute hepatic failure ": 7.77583781712053, "Acute lymphocytic leukaemia ": 6.604668079091947, "Acute myeloid leukaemia ": 11.517938374911369, "Acute promyelocytic leukaemia ": 22.85371684936645, "Agranulocytosis ": 8.878035913894303, "Alveolitis ": 87.17841772880637, "Anaemia ": 2.42120053817548, "Anti-Muellerian hormone level decreased ": 1003.0704904166596, "Aplastic anaemia ": 4.956175486850026, "Aspergillus infection ": 5.890724589947423, "Atrial fibrillation ": 2.465668338671068, "B-cell lymphoma ": 13.782308897792818, "B-cell lymphoma recurrent ": 86.78978224602395, "Bacteraemia ": 10.1551895804153, "Bicytopenia ": 23.31936433438412, "Blood follicle stimulating hormone increased ": 185.46856782293065, "Blood lactate dehydrogenase increased ": 4.7655335060127015, "Blood luteinising hormone increased ": 382.81432429938366, "Blood magnesium decreased ": 7.547550354952121, "Bone marrow failure ": 5.579113675177734, "Brain injury ": 2.690599529770381, "Brain oedema ": 4.177056157644085, "Bronchopulmonary aspergillosis ": 6.8681386893973855, "COVID-19 pneumonia ": 2.4565337170204247, "Cardiac failure ": 2.4277300173373115, "Cardiomyopathy ": 7.85212425884016, "Cardiotoxicity ": 21.588565504985556, "Central nervous system lymphoma ": 27.93473138313545, "Chemotherapy ": 24.95755586541064, "Chronic lymphocytic leukaemia recurrent ": 49.77560763297469, "Chronic myeloid leukaemia ": 5.427430558132807, "Clostridium difficile colitis ": 2.1838694768949174, "Clostridium difficile infection ": 3.1713530572825075, "Concomitant disease aggravated ": 3.822329859486565, "Congenital aplasia ": 10.629136231303564, "Cytokine release syndrome ": 5.501413541788695, "Cytomegalovirus chorioretinitis ": 9.996029640662906, "Cytomegalovirus infection ": 2.8757821022014247, "Cytomegalovirus infection reactivation ": 8.609450625438626, "Cytopenia ": 22.52108065990787, "Diffuse large B-cell lymphoma ": 34.81941064044349, "Diffuse large B-cell lymphoma recurrent ": 101.48669010949072, "Diffuse large B-cell lymphoma refractory ": 94.08617766340936, "Dilated cardiomyopathy ": 5.365205940480204, "Disease progression ": 10.28520337178969, "Disease recurrence ": 2.5475233043321355, "Drug resistance ": 2.046394853986681, "Ejection fraction decreased ": 5.2485025127004175, "Epstein-Barr virus infection reactivation ": 24.616525964638715, "Febrile bone marrow aplasia ": 14.738893388231258, "Febrile neutropenia ": 33.866760707716715, "Follicular lymphoma ": 60.85012272310657, "Gastrointestinal toxicity ": 5.511553625063246, "Granulocyte count decreased ": 34.600772447016915, "Granulocytopenia ": 22.54769059679511, "Haematotoxicity ": 7.817870414904575, "Haemoglobin decreased ": 2.874994168572329, "Haemophagocytic lymphohistiocytosis ": 3.5056478274243608, "Heart rate abnormal ": 6.062422331254474, "Hepatic failure ": 2.812731149240664, "Hepatic function abnormal ": 3.703434639682866, "Hepatitis B ": 29.3846056265272, "Hepatitis B reactivation ": 44.05824269346044, "Hepatitis fulminant ": 3.974093012982332, "Hodgkin's disease ": 8.221703260208425, "Hodgkin's disease recurrent ": 142.66811151216874, "Hormone level abnormal ": 18.69116421200922, "Hydronephrosis ": 5.047385593986239, "Hypogammaglobulinaemia ": 7.427778595904688, "Hypoxia ": 5.066251683724025, "Immune effector cell-associated neurotoxicity syndrome ": 11.979266060860573, "Immune-mediated adrenal insufficiency ": 10.378304862037805, "Inappropriate antidiuretic hormone secretion ": 2.170291675945544, "Infection ": 3.125625815851294, "Interstitial lung disease ": 7.142306990121552, "Left ventricular dysfunction ": 3.170162348835011, "Leukaemia ": 3.910483703794333, "Leukopenia ": 7.36564386485423, "Lymphadenitis ": 3.1089365297771447, "Lymphocyte count decreased ": 7.865678461439518, "Lymphoma ": 2.988285940887218, "Lymphopenia ": 4.208275759679525, "Malignant neoplasm progression ": 2.241303624174718, "Mucosal inflammation ": 6.448123299390503, "Multiple organ dysfunction syndrome ": 2.420876958207874, "Myelodysplastic syndrome ": 8.745734145159718, "Myelosuppression ": 44.27675282111058, "Neoplasm progression ": 5.393891934457058, "Neuropathy peripheral ": 2.9444090404821277, "Neutropenia ": 7.811220037767547, "Neutropenic sepsis ": 18.021746827221516, "Neutrophil count decreased ": 25.98514192103382, "Neutrophil count increased ": 3.476272047505969, "Night sweats ": 2.237001474630656, "No adverse event ": 2.1329943953204333, "Non-Hodgkin's lymphoma ": 6.806077024869822, "Oestradiol decreased ": 464.68485732743153, "Off label use ": 2.944403988934603, "Pancytopenia ": 7.601580795610622, "Papilloedema ": 8.555582261201163, "Platelet count decreased ": 6.040020972607379, "Pleural effusion ": 2.4779199941933907, "Pneumocystis jirovecii pneumonia ": 16.595479193898992, "Pneumonia ": 2.906154896568814, "Pneumonia bacterial ": 4.575871899759484, "Pneumonitis ": 3.712798630356106, "Premature baby ": 2.535419214095747, "Premature labour ": 4.6279261118858805, "Product use in unapproved indication ": 6.811129257621179, "Progressive multifocal leukoencephalopathy ": 12.903090360990753, "Pseudomonas infection ": 3.812937353762629, "Pulmonary toxicity ": 3.965623405448583, "Quadriplegia ": 18.82003183202208, "Red blood cell count decreased ": 3.606995105170477, "Respiratory failure ": 2.063369260315574, "Richter's syndrome ": 109.25620126299856, "Second primary malignancy ": 25.89722789329935, "Secondary immunodeficiency ": 28.64619921081292, "Sepsis ": 5.3972876751242, "Septic shock ": 4.488768541598368, "Staphylococcal bacteraemia ": 15.23226271758612, "Stomatitis ": 2.149192234639877, "Therapy non-responder ": 2.0900653995288225, "Therapy partial responder ": 8.310131859334078, "Thrombocytopenia ": 2.8717569825912976, "Transaminases increased ": 2.7512413253744192, "Transplant dysfunction ": 18.420336878493973, "Tumour lysis syndrome ": 15.637144222325285, "Venoocclusive liver disease ": 6.068349769367971, "White blood cell count decreased ": 18.209014711799416}
\ No newline at end of file
+{"Abortion spontaneous": 3.1330095999477057, "Aphasia": 3.722152370413929, "Blood HIV RNA increased": 161.48362298599707, "Condition aggravated": 2.037388976246975, "Depressed level of consciousness": 3.4339370663475286, "Drug interaction": 2.4446326528610127, "Drug resistance": 16.338730060176587, "Exposure during pregnancy": 6.658141928916503, "Foetal exposure during pregnancy": 6.160317009750506, "Foetal growth restriction": 11.893823751249432, "Generalised tonic-clonic seizure": 4.2633749946342725, "Gestational diabetes": 33.81449259053695, "Hepatitis C": 4.765148696447183, "Immune reconstitution inflammatory syndrome": 203.1557820626649, "Immune reconstitution inflammatory syndrome associated tuberculosis": 372.8722313325229, "Lactic acidosis": 4.342632317561691, "Leukocytosis": 6.986331431046132, "Live birth": 10.904616724138082, "Liver injury": 3.84765355622666, "Mental status changes": 5.956877568247251, "Muscular weakness": 2.306513241887995, "Nephropathy toxic": 122.68740612527888, "Pancytopenia": 2.3538100855586124, "Pathogen resistance": 83.16547948207413, "Pericardial effusion": 6.064657975868012, "Polyneuropathy": 27.501523657553747, "Premature baby": 5.612270060079436, "Progressive multifocal leukoencephalopathy": 31.865709654787818, "Psychiatric symptom": 29.68566372575558, "Renal disorder": 3.6872848184822216, "Renal impairment": 2.0599371832513715, "Renal tubular disorder": 22.02158730724053, "Skin lesion": 4.152409441463069, "Treatment noncompliance": 28.696180028118555, "Viral load increased": 25.150319199271856, "Viral mutation identified": 183.7559197868926, "Virologic failure": 213.4464445613229}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/36.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/36.json
index 72865783ebb..5c80f3c51ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/36.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/36.json
@@ -1 +1 @@
-{"Blindness transient ": 28.746271098669222, "Colitis microscopic ": 116.0068954353034, "Colorectal cancer metastatic ": 255.97948715640288, "Dehydration ": 2.335250330116739, "Diarrhoea ": 5.481201479602504, "Disease progression ": 5.819043052466748, "Endophthalmitis ": 72.65942524143358, "Hypertension ": 4.510027954330581, "Malignant neoplasm progression ": 4.271566426015454, "Metastases to liver ": 14.41295635305149, "Neuropathy peripheral ": 3.365245326465044, "Neutropenia ": 6.855846559771462, "Off label use ": 2.457966878930715, "Proteinuria ": 14.5899979923462, "Stomatitis ": 8.93862400427411, "Thrombocytopenia ": 2.995570907266436, "Visual acuity reduced ": 23.507422507729093, "Vitreous floaters ": 26.678009385094903, "Vitritis ": 64.12126205450458}
\ No newline at end of file
+{"5-hydroxyindolacetic acid": 499.4178760842281, "Abdominal hernia": 4.547060998182137, "Abdominal lymphadenopathy": 9.758587289560127, "Abdominal mass": 6.468144606178311, "Acne": 3.125640769979904, "Alveolitis": 3.190398293148186, "Anaemia": 2.15690033855101, "Aphthous ulcer": 10.51190464722891, "Ascites": 5.301072828596213, "Atelectasis": 4.082524940608525, "Atypical pneumonia": 6.170540963473899, "Biliary obstruction": 3.237410783435237, "Blood albumin decreased": 3.4621708253365675, "Blood bilirubin abnormal": 7.802089445957797, "Blood calcium increased": 2.340143614196821, "Blood cholesterol increased": 2.512456270254482, "Blood chromogranin A increased": 51.07617925634806, "Blood creatinine decreased": 2.568502658340516, "Blood creatinine increased": 2.7728374384115635, "Blood lactate dehydrogenase increased": 3.5360629969159, "Blood magnesium decreased": 2.228610808425931, "Blood phosphorus decreased": 2.572635948662627, "Blood potassium decreased": 2.130360092139089, "Blood pressure diastolic decreased": 9.091886459546034, "Blood pressure diastolic increased": 2.4993409714484405, "Blood pressure increased": 2.039883353706457, "Blood pressure systolic increased": 9.6110931999429, "Blood triglycerides increased": 5.776243748205767, "Blood urine present": 2.505111595242968, "Body temperature decreased": 6.274317741678512, "Bone cancer": 6.002953035117815, "Bone lesion": 9.947643234050572, "Bowel movement irregularity": 3.9174066656756494, "Brain neoplasm": 4.158905596908886, "Breast cancer": 7.6914945442322145, "Breast cancer female": 4.039245095720937, "Breast cancer metastatic": 30.025304783360625, "Breast cancer recurrent": 45.77802293862209, "Breast cancer stage II": 2.5558338840323898, "Breast cancer stage IV": 20.87735875708968, "Bundle branch block left": 2.113178531711932, "Cachexia": 4.86249796828422, "Cancer pain": 6.824020122833124, "Carbohydrate antigen 15-3 increased": 33.68865787589469, "Carcinoembryonic antigen increased": 9.251068153288362, "Carcinoid syndrome": 35.26055695164124, "Carcinoid tumour": 25.12297879041613, "Carcinoid tumour pulmonary": 124.09688449829794, "Cellulitis": 2.1385206277187554, "Central nervous system lesion": 2.432287287259083, "Chapped lips": 2.9392651027138585, "Cholangitis": 3.365525723288506, "Clear cell renal cell carcinoma": 10.43567843204312, "Coccydynia": 5.59290840728708, "Concomitant disease aggravated": 7.3958960701623395, "Concomitant disease progression": 9.225177086773352, "Cough": 3.4700832746350314, "Crepitations": 9.870824565774306, "Death": 3.151912110882329, "Decreased appetite": 2.292187610581883, "Dehydration": 2.5629713303267376, "Dermatitis acneiform": 2.1224246565439056, "Diabetes mellitus": 4.0808475162525495, "Disease progression": 2.9404008053310178, "Dry skin": 3.8170669719432686, "Dyslipidaemia": 2.025508381688176, "Eating disorder": 3.711686803078365, "Ejection fraction decreased": 3.0704517580104542, "Epistaxis": 2.6563495417761334, "Exposed bone in jaw": 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6.690632217436224, "Hypophagia": 3.268256810997209, "Hypophosphataemia": 2.031146082066013, "Hypoxia": 2.0754549574311936, "Ingrowing nail": 17.269352634420148, "Injection site hypersensitivity": 4.325282709791495, "Injection site mass": 2.746473342139388, "Interstitial lung disease": 18.38497704141028, "Intestinal metastasis": 18.588389484632984, "Intestinal obstruction": 3.316888197367843, "Invasive ductal breast carcinoma": 3.5070329076266646, "Iron deficiency anaemia": 2.320550473135397, "Jugular vein thrombosis": 3.0819567821269693, "KL-6 increased": 49.383574297019024, "Lip ulceration": 4.308419573735097, "Liver abscess": 2.9435361162506477, "Liver function test increased": 2.0508950950988045, "Lung consolidation": 4.912907468524892, "Lung disorder": 4.942460990996539, "Lung infiltration": 8.935591502222245, "Lung neoplasm": 6.286650000726438, "Lung opacity": 6.2941644758001, "Lymphadenopathy mediastinal": 6.463944047692348, "Lymphangiosis carcinomatosa": 35.32482778798121, "Lymphocyte count decreased": 4.704256447732936, "Lymphocyte count increased": 2.811429381483246, "Lymphoedema": 3.349610165735503, "Malignant ascites": 10.655674058665232, "Malignant neoplasm progression": 28.990484085185503, "Malignant pleural effusion": 14.985862645559529, "Mass": 2.6790957090526226, "Metastases to adrenals": 16.677758887778452, "Metastases to bone": 29.471351298415268, "Metastases to central nervous system": 16.831610834294263, "Metastases to chest wall": 48.22864251164216, "Metastases to kidney": 23.88024146973297, "Metastases to liver": 37.86024728044821, "Metastases to lung": 23.468528615121848, "Metastases to lymph nodes": 14.8963879754962, "Metastases to meninges": 4.5897413169678245, "Metastases to pancreas": 17.949701841569926, "Metastases to peritoneum": 16.392788299494537, "Metastases to pleura": 19.00590443158831, "Metastases to skin": 21.59245823015479, "Metastases to spine": 22.780305503711837, "Metastases to the mediastinum": 24.127712662245457, 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"Ovarian cyst": 2.7381745750860524, "PIK3CA-activated mutation": 39.18949146316312, "Palmar-plantar erythrodysaesthesia syndrome": 2.9565749695968706, "Pancreatic neuroendocrine tumour": 175.04485266481146, "Pancreatic neuroendocrine tumour metastatic": 97.6442848512827, "Paronychia": 5.099865559109202, "Pathological fracture": 2.2239130163867578, "Pericardial effusion": 2.946212464481739, "Platelet count decreased": 3.408985226189868, "Platelet count increased": 2.56685252510067, "Pleural effusion": 5.849229136795186, "Pleural thickening": 6.412191616901577, "Pneumocystis jirovecii pneumonia": 6.639361088191408, "Pneumonia": 2.4805128262559086, "Pneumonia bacterial": 2.5476266220056845, "Pneumonitis": 32.9257125893692, "Productive cough": 2.580357679967095, "Protein total decreased": 6.586279086080081, "Pulmonary mass": 5.010346545702173, "Pulmonary toxicity": 4.730866619484466, "Rales": 2.577428377861485, "Recurrent cancer": 6.722234962891587, "Red blood cell count decreased": 2.3737943282564853, "Red cell distribution width increased": 6.215444124540385, "Renal cancer": 5.492545130616508, "Renal cancer metastatic": 4.803927229847031, "Renal cell carcinoma": 9.649330194788348, "Renal function test abnormal": 2.125634340628813, "Renal mass": 5.286385652006783, "Respiratory rate increased": 3.131052273949986, "Second primary malignancy": 8.531098187607562, "Skin toxicity": 2.658006413235821, "Small intestinal haemorrhage": 3.531429407875461, "Small intestine neuroendocrine tumour": 113.70893985344784, "Spinal compression fracture": 2.3633560930490107, "Spinal cord compression": 2.341491718953605, "Splenic lesion": 20.32409195654913, "Steatorrhoea": 10.768433371076965, "Stomatitis": 30.12714462260718, "Taste disorder": 2.7493624911326378, "Terminal state": 2.5927326126924237, "Tongue oedema": 2.028167211359427, "Tongue ulceration": 3.830768564606766, "Tooth abscess": 2.5025125209038177, "Tumour haemorrhage": 2.132727463996519, "Tumour marker increased": 20.6044202337824, "Tumour necrosis": 8.065671243659974, "Ulcer": 2.5390521659027487, "Urine output decreased": 3.64710298360381, "Urosepsis": 3.1242499720869, "Weight decreased": 2.555687137220496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/360.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/360.json
index 83dd9c83682..eab64c52331 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/360.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/360.json
@@ -1 +1 @@
-{"Acute kidney injury ": 6.476340661338355, "Atrial fibrillation ": 10.078208180768632, "Chest pain ": 2.1209288373673143, "Confusional state ": 4.661893887688536, "Cough ": 2.304691162606193, "Drug interaction ": 15.8731762705031, "Loss of consciousness ": 4.053540175145463, "Visual impairment ": 9.381421933072788}
\ No newline at end of file
+{"Chondrolysis": 83876.61688034111, "Musculoskeletal pain": 599.3138099904689}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/361.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/361.json
index cf225b426f6..658e440bab5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/361.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/361.json
@@ -1 +1 @@
-{"Blood glucose increased ": 4.5298597944080345, "Cardio-respiratory arrest ": 14.186664753926808, "Completed suicide ": 35.94591267230228, "Hypoglycaemia ": 6.387249502111086, "Toxicity to various agents ": 8.289080547920074}
\ No newline at end of file
+{"Drug interaction": 15.707486753813953, "Respiratory failure": 15.286807432323885, "Sepsis": 14.776321272538222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/362.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/362.json
index 4085298188c..5c0bc2c9083 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/362.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/362.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 7.370304617312525, "Asthma ": 11.010746998560393, "Breath sounds abnormal ": 150.2917806829923, "Bronchiectasis ": 152.05915273796617, "Dysgeusia ": 33.53294712539142, "Flatulence ": 32.58373464757106, "Full blood count abnormal ": 52.760914489237024, "Heart rate increased ": 9.99646814652509, "Hypertension ": 4.13775575335253, "Infection ": 10.829053799311415, "Influenza ": 7.5042821959927695, "Lung disorder ": 25.7133939444531, "Lung hyperinflation ": 1217.8860284739233, "Obstructive airways disorder ": 145.00925102216425, "Productive cough ": 28.69742741506821, "Pruritus ": 4.433357667806532, "Respiratory disorder ": 37.45509240286375, "Snoring ": 360.10651294337424, "Sputum discoloured ": 162.67305660692028, "Therapeutic product effect incomplete ": 21.1836829678519, "Wheezing ": 15.941440210298564}
\ No newline at end of file
+{"Bronchial hyperreactivity": 265.38219228543363, "Gait disturbance": 2.645927813682776, "Product dose omission issue": 5.932841394173069, "Suicidal ideation": 4.502416794398693, "Weight increased": 4.002128469983708, "Wheezing": 6.495201224059108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/363.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/363.json
index c24b4f2426b..6c38d71d70c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/363.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/363.json
@@ -1 +1 @@
-{"Asthenia ": 2.578260237827025, "Feeling abnormal ": 4.188819983194419, "Gastritis ": 29.63207932518932, "Urticaria ": 3.872641258125325}
\ No newline at end of file
+{"Acquired gene mutation": 33.07876840221489, "Acute graft versus host disease": 11.27876069501697, "Acute hepatic failure": 7.77583781712053, "Acute lymphocytic leukaemia": 6.604668079091947, "Acute myeloid leukaemia": 11.517938374911369, "Acute promyelocytic leukaemia": 22.85371684936645, "Agranulocytosis": 8.878035913894303, "Alveolitis": 87.17841772880637, "Anaemia": 2.42120053817548, "Anti-Muellerian hormone level decreased": 1003.0704904166596, "Aplastic anaemia": 4.956175486850026, "Aspergillus infection": 5.890724589947423, "Atrial fibrillation": 2.465600933031637, "B-cell lymphoma": 13.782308897792818, "B-cell lymphoma recurrent": 86.78978224602395, "Bacteraemia": 10.1551895804153, "Bicytopenia": 23.31936433438412, "Blood follicle stimulating hormone increased": 185.46856782293065, "Blood lactate dehydrogenase increased": 4.7655335060127015, "Blood luteinising hormone increased": 382.81432429938366, "Blood magnesium decreased": 7.547550354952121, "Bone marrow failure": 5.579113675177734, "Brain injury": 2.690599529770381, "Brain oedema": 4.177056157644085, "Bronchopulmonary aspergillosis": 6.8681386893973855, "COVID-19 pneumonia": 2.4565337170204247, "Cardiac failure": 2.427508084502377, "Cardiomyopathy": 7.85212425884016, "Cardiotoxicity": 21.588565504985556, "Central nervous system lymphoma": 27.93473138313545, "Chemotherapy": 24.95755586541064, "Chronic lymphocytic leukaemia recurrent": 49.77560763297469, "Chronic myeloid leukaemia": 5.427430558132807, "Clostridium difficile colitis": 2.1838694768949174, "Clostridium difficile infection": 3.1713530572825075, "Concomitant disease aggravated": 3.822329859486565, "Congenital aplasia": 10.595759792540417, "Cytokine release syndrome": 5.501413541788695, "Cytomegalovirus chorioretinitis": 9.996029640662906, "Cytomegalovirus infection": 2.8757821022014247, "Cytomegalovirus infection reactivation": 8.609450625438626, "Cytopenia": 22.50289046466196, "Diffuse large B-cell lymphoma": 34.81941064044349, "Diffuse large B-cell lymphoma recurrent": 101.48669010949072, "Diffuse large B-cell lymphoma refractory": 94.08617766340936, "Dilated cardiomyopathy": 5.365205940480204, "Disease progression": 10.28520337178969, "Disease recurrence": 2.5475233043321355, "Drug resistance": 2.046394853986681, "Ejection fraction decreased": 5.2485025127004175, "Epstein-Barr virus infection reactivation": 24.616525964638715, "Febrile bone marrow aplasia": 14.738893388231258, "Febrile neutropenia": 33.866760707716715, "Follicular lymphoma": 60.85012272310657, "Gastrointestinal toxicity": 5.511553625063246, "Granulocyte count decreased": 34.600772447016915, "Granulocytopenia": 22.541093690697405, "Haematotoxicity": 7.817870414904575, "Haemoglobin decreased": 2.874994168572329, "Haemophagocytic lymphohistiocytosis": 3.5056478274243608, "Heart rate abnormal": 6.062422331254474, "Hepatic failure": 2.812731149240664, "Hepatic function abnormal": 3.703434639682866, "Hepatitis B": 29.3846056265272, "Hepatitis B reactivation": 44.05824269346044, "Hepatitis fulminant": 3.974093012982332, "Hodgkin's disease": 8.221703260208425, "Hodgkin's disease recurrent": 142.66811151216874, "Hormone level abnormal": 18.69116421200922, "Hydronephrosis": 5.047385593986239, "Hypogammaglobulinaemia": 7.427778595904688, "Hypoxia": 5.066251683724025, "Immune effector cell-associated neurotoxicity syndrome": 11.979266060860573, "Immune-mediated adrenal insufficiency": 10.378304862037805, "Inappropriate antidiuretic hormone secretion": 2.170291675945544, "Infection": 3.125625815851294, "Interstitial lung disease": 7.142306990121552, "Left ventricular dysfunction": 3.170162348835011, "Leukaemia": 3.910483703794333, "Leukopenia": 7.364710802785722, "Lymphadenitis": 3.108217167269122, "Lymphocyte count decreased": 7.865678461439518, "Lymphoma": 2.988285940887218, "Lymphopenia": 4.208275759679525, "Malignant neoplasm progression": 2.241303624174718, "Mucosal inflammation": 6.448123299390503, "Multiple organ dysfunction syndrome": 2.420876958207874, "Myelodysplastic syndrome": 8.745734145159718, "Myelosuppression": 44.27675282111058, "Neoplasm progression": 5.393891934457058, "Neuropathy peripheral": 2.9443194871489795, "Neutropenia": 7.8108823664104, "Neutropenic sepsis": 18.021746827221516, "Neutrophil count decreased": 25.98514192103382, "Neutrophil count increased": 3.476272047505969, "Night sweats": 2.237001474630656, "No adverse event": 2.1329943953204333, "Non-Hodgkin's lymphoma": 6.806077024869822, "Oestradiol decreased": 464.68485732743153, "Off label use": 2.9442877927168305, "Pancytopenia": 7.601580795610622, "Papilloedema": 8.555582261201163, "Platelet count decreased": 6.040020972607379, "Pleural effusion": 2.4776915175397067, "Pneumocystis jirovecii pneumonia": 16.595479193898992, "Pneumonia": 2.906154896568814, "Pneumonia bacterial": 4.575871899759484, "Pneumonitis": 3.712798630356106, "Premature baby": 2.535419214095747, "Premature labour": 4.6279261118858805, "Product use in 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/364.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/364.json
index 4ce413fbe60..534cd50616f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/364.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/364.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.7440667201091835, "Blood glucose abnormal ": 19.629489300989093, "Blood glucose decreased ": 30.379715554242512, "Blood glucose increased ": 22.68334547056177, "Cardiac disorder ": 2.429750586831433, "Cataract ": 2.9450859652712165, "Cellulitis ": 3.09051085911194, "Cerebrovascular accident ": 2.6034540028882702, "Constipation ": 2.36610632202812, "Decreased appetite ": 3.279079030128049, "Dehydration ": 4.892722758747175, "Diabetes mellitus inadequate control ": 10.528916639845542, "Diabetic ketoacidosis ": 9.271060300581452, "Diarrhoea ": 2.325805183780601, "Drug hypersensitivity ": 2.3909662061345096, "Dyspepsia ": 2.1982740200428776, "Eructation ": 14.119817142015128, "Gait inability ": 2.255597690945153, "Gastrointestinal disorder ": 2.0441169085705804, "Gastrooesophageal reflux disease ": 3.5689845901352006, "Genital tract inflammation ": 180.75724255187797, "Glaucoma ": 5.539507622759449, "Glycosylated haemoglobin increased ": 44.57301064512043, "Hypoglycaemia ": 6.799041223318199, "Illness ": 3.139698331516847, "Inappropriate schedule of product administration ": 2.350372917760858, "Incorrect dose administered ": 8.015056903867183, "Injection site pruritus ": 4.156081596373442, "Ketoacidosis ": 19.77850962049849, "Lactic acidosis ": 2.6397498231605625, "Mobility decreased ": 2.2595781674827027, "Neoplasm malignant ": 2.397209023425353, "Neuropathy peripheral ": 2.1249856620950567, "Pancreatitis ": 6.625808673154866, "Pancreatitis acute ": 3.0738798159934837, "Pollakiuria ": 3.5565773784015, "Product dose omission issue ": 2.4949890514187483, "Renal disorder ": 2.627784296921303, "Skin ulcer ": 5.764553801261481, "Visual impairment ": 3.26031759834686, "Weight decreased ": 4.430660073619064, "Weight increased ": 2.3618392113997864}
\ No newline at end of file
+{"Acute kidney injury": 6.476340661338355, "Atrial fibrillation": 10.077933089280462, "Chest pain": 2.1209288373673143, "Confusional state": 4.661893887688536, "Cough": 2.30466978809594, "Drug interaction": 15.8731762705031, "Loss of consciousness": 4.053341819898194, "Visual impairment": 9.381421933072788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/365.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/365.json
index 0e6d1c68f4f..6c50cda46f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/365.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/365.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 2.33540262003294, "Abulia ": 16.241065931820852, "Accidental overdose ": 3.073563277539737, "Acidosis ": 2.798329747765377, "Acute hepatic failure ": 2.0614405500584096, "Adrenal insufficiency ": 2.367037650201471, "Affective disorder ": 8.703659211682718, "Agitation ": 2.9220561987273146, "Akathisia ": 5.00824402245491, "Allodynia ": 11.698582920616234, "Altered state of consciousness ": 2.6516467344898915, "Angina pectoris ": 2.3807514556505818, "Antidepressant discontinuation syndrome ": 167.80463970365986, "Aortic valve stenosis ": 12.79745250913199, "Apathy ": 3.510957663587796, "Apnoea ": 5.05800065086327, "Arteriosclerosis coronary artery ": 6.049461304118168, "Blood pressure systolic increased ": 2.02288362180228, "Blood urine present ": 6.927795571262581, "Body temperature decreased ": 3.8481525265923953, "Bradyphrenia ": 9.696719647888068, "Brain death ": 17.729462386943073, "Brain injury ": 4.323075393314609, "Bronchiectasis ": 3.066395493170857, "Bursitis ": 2.761668199212698, "Cardiac arrest ": 3.1270333865134563, "Cardio-respiratory arrest ": 11.185779413143392, "Cardiomegaly ": 12.28176667648121, "Carpal tunnel syndrome ": 6.568388078457318, "Cholecystectomy ": 6.616498558214437, "Cholestasis of pregnancy ": 59.23908790386782, "Clonus ": 24.144682256803627, "Coma ": 7.237935322015623, "Coma scale abnormal ": 5.016225245911374, "Completed suicide ": 25.13490383338429, "Constipation ": 2.301881080232821, "Coronary artery stenosis ": 8.301657296933135, "Cystitis ": 3.403768302647122, "Delirium ": 2.854205018602868, "Delusion ": 4.684125185312821, "Depressed level of consciousness ": 2.8919819898296577, "Depressed mood ": 2.527195440901173, "Depression ": 2.5895801890195767, "Depressive symptom ": 5.465659993620178, "Dissociation ": 7.759396737435632, "Dissociative disorder ": 53.95453967572305, "Disturbance in attention ": 3.5716124085558034, "Drug abuse ": 3.4659486246452924, "Drug interaction ": 6.582639131161493, "Drug level increased ": 2.944671805267814, "Drug tolerance ": 5.531453217961254, "Drug withdrawal syndrome neonatal ": 2.7724898265166438, "Dry mouth ": 2.017010368360685, "Dyskinesia ": 2.688688273937133, "Dysstasia ": 3.626742721258669, "Dystonia ": 4.372915530196339, "Electric shock sensation ": 3.0863214167963595, "Electrocardiogram QT prolonged ": 2.73235471006202, "Electrolyte imbalance ": 5.166635126867194, "Electronic cigarette user ": 956.7971746578976, "Emphysema ": 2.745102326447888, "Eyelid myoclonus ": 122.53886769714096, "Fear ": 7.864310341636544, "Feeling guilty ": 19.147208611134143, "Food allergy ": 4.949228749046713, "Gastrooesophageal reflux disease ": 5.4096615299870985, "Gestational diabetes ": 7.683572907721872, "Gingival abscess ": 48.84871061602784, "Hallucination, auditory ": 3.1190872412376005, "Hallucination, visual ": 2.1632417339479155, "Hepatic failure ": 2.013705429251732, "Hepatic steatosis ": 3.285390202804205, "Hyperaesthesia ": 2.758122219256395, "Hyperreflexia ": 17.43576302141707, "Hypocalcaemia ": 2.8516948771703485, "Hypokinesia ": 6.30601073742953, "Hyponatraemia ": 2.5893723932869435, "Impaired quality of life ": 22.18324739720747, "Inappropriate antidiuretic hormone secretion ": 9.481040121298316, "Injury ": 2.093390179146755, "Intentional overdose ": 5.329987568566059, "Intentional self-injury ": 8.799847906756787, "Intervertebral disc degeneration ": 5.0384384093659165, "Intrusive thoughts ": 47.56381421089704, "Irritability ": 2.4445471083525523, "Joint contracture ": 9.870709952113874, "Joint noise ": 14.122940453543968, "Ketonuria ": 14.911697593254065, "Loss of control of legs ": 46.913153769197685, "Loss of libido ": 4.700682719295856, "Lung cyst ": 72.77981611879493, "Major depression ": 7.223976878819252, "Mania ": 3.266831703684594, "Medication error ": 2.1409719353601835, "Mental disorder ": 3.951452673353805, "Mental impairment ": 4.190555203252156, "Mental status changes ": 3.4676443170201927, "Miosis ": 2.281697224267688, "Mitral valve incompetence ": 2.4114463125913623, "Muscle atrophy ": 2.764969075324298, "Muscle rigidity ": 2.400528545968396, "Mydriasis ": 6.1913511874763145, "Myoclonus ": 5.931528322613611, "Needle issue ": 2.8460085412569383, "Neuroleptic malignant syndrome ": 2.419431431127692, "Obsessive thoughts ": 21.600923040193592, "Obsessive-compulsive disorder ": 5.97528600717863, "Oesophageal perforation ": 69.61531964138896, "Osteoarthritis ": 3.0157357219979115, "Overdose ": 3.808189700567137, "Panic attack ": 2.3384774351807143, "Persecutory delusion ": 10.919322025908905, "Pneumonia aspiration ": 15.705589249832462, "Poisoning ": 5.766179691677862, "Polyuria ": 3.708370171811969, "Pre-eclampsia ": 18.22811845102764, "Pulmonary mass ": 4.305625990809034, "Red cell distribution width increased ": 11.59757426357904, "Reduced facial expression ": 33.32561499749154, "Respiratory arrest ": 7.058294187611319, "Respiratory depression ": 5.310389538936418, "Respiratory tract malformation ": 179.58971186388027, "Reversible airways obstruction ": 368.35045376148594, "Reversible cerebral vasoconstriction syndrome ": 34.862011505669614, "Rhabdomyolysis ": 2.137670244165941, "Rotator cuff syndrome ": 3.55087542975524, "Scoliosis ": 3.9648033262674818, "Sedation ": 4.798771613489257, "Self-injurious ideation ": 10.122079284943467, "Serotonin syndrome ": 31.358569084377606, "Sexual dysfunction ": 5.6430888393973415, "Sinus tachycardia ": 2.338144417202312, "Skin atrophy ": 4.654891398941683, "Sleep apnoea syndrome ": 5.096145714019685, "Sluggishness ": 4.876072645790343, "Somnolence ": 3.277546102649138, "Suicidal ideation ": 4.345242159670056, "Suicide attempt ": 4.8463871528996485, "Suspected suicide ": 66.92622136856298, "Tardive dyskinesia ": 3.277296277384931, "Thinking abnormal ": 4.828323112312553, "Toxicity to various agents ": 17.477344576080725, "Treatment failure ": 2.58561125953696, "Urinary retention ": 2.0879347173852185, "Urine odour abnormal ": 14.264191576187356, "Weight increased ": 2.663389281221831, "Wrong patient ": 37.16188634865584}
\ No newline at end of file
+{"Blood glucose increased": 4.5298597944080345, "Cardio-respiratory arrest": 14.186664753926808, "Completed suicide": 35.94591267230228, "Hypoglycaemia": 6.387033899506927, "Toxicity to various agents": 8.289080547920074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/366.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/366.json
index 984a52d80b0..0fe68a2b9bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/366.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/366.json
@@ -1 +1 @@
-{"Acute kidney injury ": 10.280441326272848, "Anaemia ": 14.75399969677695, "Cerebral haemorrhage ": 12.375280399412684, "Epistaxis ": 9.883986237489244, "Gastrointestinal haemorrhage ": 10.826895796243075, "Haematoma ": 10.158495994559376, "Hyperkalaemia ": 19.34434890240969, "Lactic acidosis ": 35.72516020539575, "Melaena ": 19.36354366868858, "Rectal haemorrhage ": 18.933622390184794}
\ No newline at end of file
+{"Abdominal discomfort": 7.370304617312525, "Asthma": 11.010746998560393, "Breath sounds abnormal": 150.2917806829923, "Bronchiectasis": 152.05915273796617, "Dysgeusia": 33.53294712539142, "Flatulence": 32.581086240564545, "Full blood count abnormal": 52.760914489237024, "Heart rate increased": 9.99646814652509, "Hypertension": 4.137713041980857, "Infection": 10.829053799311415, "Influenza": 7.5042821959927695, "Lung disorder": 25.7133939444531, "Lung hyperinflation": 1217.8860284739233, "Obstructive airways disorder": 145.00925102216425, "Productive cough": 28.69742741506821, "Pruritus": 4.433303971472504, "Respiratory disorder": 37.45509240286375, "Snoring": 360.10651294337424, "Sputum discoloured": 162.67305660692028, "Therapeutic product effect incomplete": 21.1836829678519, "Wheezing": 15.940806258643969}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/367.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/367.json
index aaadfffa12b..57380bfbd12 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/367.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/367.json
@@ -1 +1 @@
-{"Asthma ": 14.38718825501912, "Chest discomfort ": 2.563358349095402, "Chronic obstructive pulmonary disease ": 11.451790987034324, "Condition aggravated ": 4.789880979388072, "Cough ": 5.89189519647757, "Device malfunction ": 29.951979733903997, "Drug ineffective ": 2.7178788020114344, "Dysphonia ": 15.472144797166589, "Dyspnoea ": 5.28626974991273, "Muscle spasms ": 8.956379816784567, "Oral candidiasis ": 16.35545172849498, "Oropharyngeal pain ": 6.5982924514366985, "Palpitations ": 2.491452297440771, "Product quality issue ": 24.653601987947177, "Product substitution issue ": 100.00162811000044, "Therapeutic product effect incomplete ": 3.9154178181483377, "Therapeutic response unexpected ": 19.4351307566344, "Tremor ": 3.146140616221603, "Wheezing ": 5.809949516841132}
\ No newline at end of file
+{"Asthenia": 2.578157686152075, "Feeling abnormal": 4.188739365827474, "Gastritis": 29.63207932518932, "Urticaria": 3.872601583118877}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/368.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/368.json
index 5003fddf8f2..f8f0e2a8a3e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/368.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/368.json
@@ -1 +1 @@
-{"Pemphigoid ": 440.691716296677}
\ No newline at end of file
+{"Abdominal distension": 2.7440667201091835, "Blood glucose abnormal": 19.629489300989093, "Blood glucose decreased": 30.379715554242512, "Blood glucose increased": 22.68334547056177, "Cardiac disorder": 2.429750586831433, "Cataract": 2.9450859652712165, "Cellulitis": 3.09051085911194, "Cerebrovascular accident": 2.603407077300868, "Constipation": 2.36610632202812, "Decreased appetite": 3.279047211389719, "Dehydration": 4.892461458647581, "Diabetes mellitus inadequate control": 10.528916639845542, "Diabetic ketoacidosis": 9.271060300581452, "Diarrhoea": 2.3257857685819743, "Drug hypersensitivity": 2.3909662061345096, "Dyspepsia": 2.1982740200428776, "Eructation": 14.119817142015128, "Gait inability": 2.255597690945153, "Gastrointestinal disorder": 2.0440525430072163, "Gastrooesophageal reflux disease": 3.5689845901352006, "Genital tract inflammation": 180.75724255187797, "Glaucoma": 5.539507622759449, "Glycosylated haemoglobin increased": 44.57301064512043, "Hypoglycaemia": 6.798811512884453, "Illness": 3.139698331516847, "Inappropriate schedule of product administration": 2.350372917760858, "Incorrect dose administered": 8.015056903867183, "Injection site pruritus": 4.156081596373442, "Ketoacidosis": 19.77850962049849, "Lactic acidosis": 2.6397498231605625, "Mobility decreased": 2.2595781674827027, "Neoplasm malignant": 2.397209023425353, "Neuropathy peripheral": 2.124921147476848, "Pancreatitis": 6.625808673154866, "Pancreatitis acute": 3.0738798159934837, "Pollakiuria": 3.5565773784015, "Product dose omission issue": 2.4949890514187483, "Renal disorder": 2.6273966924663115, "Skin ulcer": 5.764553801261481, "Visual impairment": 3.26031759834686, "Weight decreased": 4.430660073619064, "Weight increased": 2.3618392113997864}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/369.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/369.json
index 465f52bc4b9..902067f320c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/369.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/369.json
@@ -1 +1 @@
-{"Asthma ": 5.484930631895915, "Chest discomfort ": 2.332590888266992, "Dermatitis atopic ": 151.26746399987078, "Eosinophil count increased ": 29.744665725515546, "Gestational hypertension ": 532.0404063831385, "Infection ": 3.591200522643096, "Maternal exposure before pregnancy ": 155.54580913172757, "Maternal exposure during pregnancy ": 6.654305319862672, "Premature delivery ": 52.25794809196569, "Steroid diabetes ": 586.56256011252}
\ No newline at end of file
+{"Abnormal behaviour": 2.334526815687807, "Abulia": 16.234975907081346, "Accidental overdose": 3.0724106177619634, "Acidosis": 2.797280430272345, "Acute hepatic failure": 2.0606675511569503, "Adrenal insufficiency": 2.366150027881064, "Affective disorder": 8.700395264656668, "Agitation": 2.9209601876313047, "Akathisia": 5.006365863085079, "Allodynia": 11.694196249390338, "Altered state of consciousness": 2.650652268560339, "Angina pectoris": 2.379858591444589, "Antidepressant discontinuation syndrome": 167.74171707548206, "Aortic valve stenosis": 12.792653790343785, "Apathy": 3.509641012058608, "Apnoea": 5.056103847976727, "Arteriosclerosis coronary artery": 6.047192765712661, "Blood pressure systolic increased": 2.0221250672520936, "Blood urine present": 6.925197474181946, "Body temperature decreased": 3.846709496986099, "Bradyphrenia": 9.693083264286235, "Brain death": 17.72281390987343, "Brain injury": 4.321454254520612, "Bronchiectasis": 3.06524566389532, "Bursitis": 2.760632553521189, "Cardiac arrest": 3.1258604645990458, "Cardio-respiratory arrest": 11.181583007596236, "Cardiomegaly": 12.277160380018277, "Carpal tunnel syndrome": 6.565924875689567, "Cholecystectomy": 6.614017419597487, "Cholestasis of pregnancy": 59.216874720782485, "Clonus": 24.135627420726333, "Coma": 7.235220120236009, "Coma scale abnormal": 5.014344274806026, "Completed suicide": 25.12546769131355, "Constipation": 2.301017620264553, "Coronary artery stenosis": 8.298544270379482, "Cystitis": 3.402491837883087, "Delirium": 2.853134565168247, "Delusion": 4.682368589519128, "Depressed level of consciousness": 2.890897332772154, "Depressed mood": 2.52624763347782, "Depression": 2.588608723218272, "Depressive symptom": 5.463610432885307, "Dissociation": 7.75648710298764, "Dissociative disorder": 53.934306565072106, "Disturbance in attention": 3.5702727080684618, "Drug abuse": 3.464648549680456, "Drug interaction": 6.580168705234447, "Drug level increased": 2.9435675176806075, "Drug tolerance": 5.529379048135286, "Drug withdrawal syndrome neonatal": 2.7714501796719166, "Dry mouth": 2.016253875090787, "Dyskinesia": 2.6876799440181958, "Dysstasia": 3.624555366428411, "Dystonia": 4.371275662707695, "Electric shock sensation": 3.08516408078946, "Electrocardiogram QT prolonged": 2.7313299526828025, "Electrolyte imbalance": 5.1646976191580976, "Electronic cigarette user": 956.4384185854618, "Emphysema": 2.744072968163017, "Eyelid myoclonus": 122.49291959124122, "Fear": 7.861360926423039, "Feeling guilty": 19.140028951227123, "Food allergy": 4.947372804998524, "Gastrooesophageal reflux disease": 5.407632322925554, "Gestational diabetes": 7.680691723769849, "Gingival abscess": 48.83039354485118, "Hallucination, auditory": 3.1179175768060383, "Hallucination, visual": 2.162430506084715, "Hepatic failure": 2.012950262084958, "Hepatic steatosis": 3.284158157640713, "Hyperaesthesia": 2.757087954233844, "Hyperreflexia": 17.42922420826344, "Hypocalcaemia": 2.8506255175982385, "Hypokinesia": 6.303645766739907, "Hyponatraemia": 2.588401168223593, "Impaired quality of life": 22.16618899542657, "Inappropriate antidiuretic hormone secretion": 9.477484372004122, "Injury": 2.0923009555916376, "Intentional overdose": 5.327988063727441, "Intentional self-injury": 8.796547488127727, "Intervertebral disc degeneration": 5.036549041447541, "Intrusive thoughts": 47.54597871822317, "Irritability": 2.443513382002993, "Joint contracture": 9.86700866104979, "Joint noise": 14.11764451627266, "Ketonuria": 14.906106087745398, "Loss of control of legs": 46.89556027241154, "Loss of libido": 4.698920016222589, "Lung cyst": 72.75252572028427, "Major depression": 7.221267848681291, "Mania": 3.2656066291112675, "Medication error": 2.1400152344802525, "Mental disorder": 3.949970722580476, "Mental impairment": 4.188983650947622, "Mental status changes": 3.466343919589021, "Miosis": 2.280841633549234, "Mitral valve incompetence": 2.4105420685798906, "Muscle atrophy": 2.7639322609405164, "Muscle rigidity": 2.3996283696031946, "Mydriasis": 6.189029275228009, "Myoclonus": 5.929303810763567, "Needle issue": 2.8449413520991005, "Neuroleptic malignant syndrome": 2.418524139041924, "Obsessive thoughts": 21.592823000036383, "Obsessive-compulsive disorder": 5.973045318394958, "Oesophageal perforation": 69.58921474775084, "Osteoarthritis": 3.014604740611936, "Overdose": 3.806761020111919, "Panic attack": 2.337600477742967, "Persecutory delusion": 10.915227383996749, "Pneumonia aspiration": 15.699697998369365, "Poisoning": 5.764017352674314, "Polyuria": 3.706979538426262, "Pre-eclampsia": 18.221282538468664, "Pulmonary mass": 4.304011357253837, "Red cell distribution width increased": 11.593225283906843, "Reduced facial expression": 33.313117930687774, "Respiratory arrest": 7.05564681564225, "Respiratory depression": 5.308398001884131, "Respiratory tract malformation": 179.52236981638814, "Reversible airways obstruction": 368.2123052702108, "Reversible cerebral vasoconstriction syndrome": 34.84893835710709, "Rhabdomyolysis": 2.136868535775965, "Rotator cuff syndrome": 3.549543906534609, "Scoliosis": 3.96331662448424, "Sedation": 4.796971914906846, "Self-injurious ideation": 10.118283643206013, "Serotonin syndrome": 31.346803260871205, "Sexual dysfunction": 5.640972679684298, "Sinus tachycardia": 2.3372676296358885, "Skin atrophy": 4.653145931582041, "Sleep apnoea syndrome": 5.09197009709474, "Sluggishness": 4.874244183823887, "Somnolence": 3.276280127604587, "Suicidal ideation": 4.343612118592013, "Suicide attempt": 4.844569136809384, "Suspected suicide": 66.9011156476248, "Tardive dyskinesia": 3.276067342062273, "Thinking abnormal": 4.826512456520859, "Toxicity to various agents": 17.49001420697533, "Treatment failure": 2.5846415115748558, "Urinary retention": 2.0871516776420598, "Urine odour abnormal": 14.258842457291031, "Weight increased": 2.66239020154284, "Wrong patient": 37.14795153247491}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/37.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/37.json
index da206672577..c4aaaf35637 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/37.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/37.json
@@ -1 +1 @@
-{"Blood pressure increased ": 6.42932868638543, "Heart rate increased ": 9.13627834487562, "Infusion related reaction ": 17.317630442395497}
\ No newline at end of file
+{"Blindness transient": 28.746271098669222, "Colitis microscopic": 116.0068954353034, "Colorectal cancer metastatic": 255.97948715640288, "Dehydration": 2.335125697382217, "Diarrhoea": 5.481155724762733, "Disease progression": 5.819043052466748, "Endophthalmitis": 72.65942524143358, "Hypertension": 4.509981388643912, "Malignant neoplasm progression": 4.271566426015454, "Metastases to liver": 14.41295635305149, "Neuropathy peripheral": 3.3651431710500805, "Neutropenia": 6.855551668913844, "Off label use": 2.4578700634038286, "Proteinuria": 14.5899979923462, "Stomatitis": 8.93862400427411, "Thrombocytopenia": 2.9952891095549568, "Visual acuity reduced": 23.507422507729093, "Vitreous floaters": 26.678009385094903, "Vitritis": 64.12126205450458}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/370.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/370.json
index 912299d043c..0b711ed2293 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/370.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/370.json
@@ -1 +1 @@
-{"Asthma ": 8.733155971240059, "Bronchitis ": 2.687965300865257, "Cataract ": 7.502553720239467, "Cellulitis ": 3.070157786095242, "Chest discomfort ": 2.4467281931639677, "Cough ": 2.280601079264091, "Dermatitis atopic ": 59.5831003354255, "Drug hypersensitivity ": 5.401512033901239, "Dry eye ": 5.376112115363782, "Dry skin ": 5.382447301237019, "Eczema ": 3.694088681694117, "Eosinophil count increased ": 16.1346065222669, "Eosinophilia ": 4.676493960660832, "Eye disorder ": 4.414523749454035, "Eye infection ": 54.53690993932045, "Eye pain ": 4.082846102819229, "Full blood count abnormal ": 3.3888005614164407, "Hospitalisation ": 5.066538717516255, "Illness ": 3.634660844363245, "Infection ": 2.070912006595261, "Loss of personal independence in daily activities ": 5.512050455085209, "Nasal congestion ": 3.884888540408189, "Oxygen saturation decreased ": 3.359134245777305, "Product dose omission issue ": 4.201825768050174, "Product use in unapproved indication ": 5.137552184693401, "Product use issue ": 2.9713349226775883, "Productive cough ": 4.169174404013628, "Psoriasis ": 3.623032255377798, "Rash vesicular ": 9.657588786118367, "Sinusitis ": 4.080952029629663, "Skin discolouration ": 4.150812689807531, "Skin exfoliation ": 4.940260220829432, "Sleep disorder due to a general medical condition ": 7.551327766714572, "Syringe issue ": 37.55296402332177, "Therapeutic product effect incomplete ": 3.41657850774348, "Therapeutic response decreased ": 3.349835825989292, "Wheezing ": 5.745217013665631}
\ No newline at end of file
+{"Acute kidney injury": 10.280441326272848, "Anaemia": 14.75399969677695, "Cerebral haemorrhage": 12.375280399412684, "Epistaxis": 9.883986237489244, "Gastrointestinal haemorrhage": 10.826895796243075, "Haematoma": 10.158495994559376, "Hyperkalaemia": 19.341681463792632, "Lactic acidosis": 35.72516020539575, "Melaena": 19.36104701042718, "Rectal haemorrhage": 18.933622390184794}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/371.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/371.json
index 05eed12b7e8..f68742e6e30 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/371.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/371.json
@@ -1 +1 @@
-{"Febrile neutropenia ": 19.157564658482517, "Malignant neoplasm progression ": 12.685740063035697, "Off label use ": 2.2341095405572955}
\ No newline at end of file
+{"Asthma": 14.396171720372967, "Chest discomfort": 2.5076864049086467, "Chronic obstructive pulmonary disease": 11.203397740782124, "Condition aggravated": 4.685879220305721, "Cough": 5.914663417683261, "Device malfunction": 29.30231259500156, "Drug ineffective": 2.6587706286163497, "Dysphonia": 15.13635001785534, "Dyspnoea": 5.234688585931754, "Muscle spasms": 8.761846403899089, "Oral candidiasis": 16.000916268836836, "Oropharyngeal pain": 6.455111128136311, "Palpitations": 2.437406849605376, "Product quality issue": 24.11862619415123, "Product substitution issue": 97.82665079169182, "Therapeutic product effect incomplete": 3.830543587127224, "Therapeutic response unexpected": 19.013576572718616, "Tremor": 3.077759465794965, "Wheezing": 6.244032970582567}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/372.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/372.json
index b4e7ac962e7..d0faae562c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/372.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/372.json
@@ -1 +1 @@
-{"Hepatic function abnormal ": 71.56504306676347}
\ No newline at end of file
+{"Pemphigoid": 440.691716296677}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/373.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/373.json
index b3766c88938..198e88115c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/373.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/373.json
@@ -1 +1 @@
-{"Vomiting ": 9.534573366778202}
\ No newline at end of file
+{"Asthma": 5.484930631895915, "Chest discomfort": 2.332509030211587, "Dermatitis atopic": 151.26746399987078, "Eosinophil count increased": 29.744665725515546, "Gestational hypertension": 532.0404063831385, "Infection": 3.591200522643096, "Maternal exposure before pregnancy": 155.54580913172757, "Maternal exposure during pregnancy": 6.654305319862672, "Premature delivery": 52.25794809196569, "Steroid diabetes": 586.56256011252}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/374.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/374.json
index 362a36c259d..70b1b13122b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/374.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/374.json
@@ -1 +1 @@
-{"Accidental overdose ": 8.563238953198683, "Aggression ": 11.19836694141282, "Agitation ": 12.37714292818611, "Altered state of consciousness ": 2.9400648935380524, "Apathy ": 6.05920944286743, "Ataxia ": 5.481837706584559, "Atrioventricular block ": 11.995956631558204, "Atrioventricular block complete ": 11.699135892539786, "Atrioventricular block second degree ": 27.534798862086973, "Balance disorder ": 6.028040318918639, "Behaviour disorder ": 21.011946629007557, "Blood alkaline phosphatase increased ": 2.568667128763497, "Blood bilirubin increased ": 2.2125006369891635, "Bradycardia ": 13.996402436069182, "C-reactive protein increased ": 2.0664902694829395, "Cardiac failure ": 3.715836983408749, "Coma ": 2.5440764636835174, "Confusional state ": 11.074438934625292, "Deep vein thrombosis ": 3.4092784052383385, "Dehydration ": 2.7112192767429875, "Delirium ": 4.159166451388753, "Dementia ": 7.231702824859253, "Dementia Alzheimer's type ": 17.77008851652304, "Depressed level of consciousness ": 2.954448195420037, "Disorientation ": 3.7591287089948553, "Eosinophilia ": 5.388159224928923, "Epilepsy ": 10.046585547440008, "Extrapyramidal disorder ": 9.32988702400309, "Fall ": 10.078910785892615, "Gait disturbance ": 4.342091129024138, "Gamma-glutamyltransferase increased ": 3.5665522441535016, "Generalised tonic-clonic seizure ": 5.556787290429658, "Haemolytic anaemia ": 6.088372109860061, "Hallucination ": 9.62757607162916, "Hallucination, visual ": 10.993170097526582, "Head discomfort ": 3.262171527426476, "Hepatic cytolysis ": 10.286120693337152, "Jaundice ": 2.302326844018302, "Leukopenia ": 3.041880708768073, "Loss of consciousness ": 2.58957657434998, "Medication error ": 2.4363366817870347, "Myoclonus ": 10.89927844007874, "Nightmare ": 3.1652504543469275, "Orthostatic hypotension ": 9.314002832566068, "Pancreatitis ": 2.5104449071063395, "Pancreatitis acute ": 6.577299342398249, "Phlebitis ": 12.852828780432867, "Product administration interrupted ": 92.2203453366499, "Psychomotor hyperactivity ": 6.641989223716157, "Pulmonary embolism ": 5.497713825080997, "Seizure ": 5.259403588381565, "Sinus bradycardia ": 14.31911589364448, "Somnolence ": 5.354971726479438, "Speech disorder ": 4.3768628219594525, "Syncope ": 2.8472773460302787, "Transaminases increased ": 3.496207777180764, "Upper gastrointestinal haemorrhage ": 5.841939044505608, "Urinary retention ": 3.4123145560250343}
\ No newline at end of file
+{"Asthma": 8.733155971240059, "Bronchitis": 2.68780412807896, "Cataract": 7.502553720239467, "Cellulitis": 3.070157786095242, "Chest discomfort": 2.446642298824605, "Cough": 2.280579920514072, "Dermatitis atopic": 59.5831003354255, "Drug hypersensitivity": 5.401512033901239, "Dry eye": 5.376112115363782, "Dry skin": 5.382447301237019, "Eczema": 3.694088681694117, "Eosinophil count increased": 16.1346065222669, "Eosinophilia": 4.676493960660832, "Eye disorder": 4.414523749454035, "Eye infection": 54.53690993932045, "Eye pain": 4.082846102819229, "Full blood count abnormal": 3.3888005614164407, "Hospitalisation": 5.066538717516255, "Illness": 3.634660844363245, "Infection": 2.070912006595261, "Loss of personal independence in daily activities": 5.512050455085209, "Nasal congestion": 3.884888540408189, "Oxygen saturation decreased": 3.3589544788040366, "Product dose omission issue": 4.201825768050174, "Product use in unapproved indication": 5.137391852295288, "Product use issue": 2.9713349226775883, "Productive cough": 4.169174404013628, "Psoriasis": 3.623032255377798, "Rash vesicular": 9.657588786118367, "Sinusitis": 4.080952029629663, "Skin discolouration": 4.150812689807531, "Skin exfoliation": 4.940260220829432, "Sleep disorder due to a general medical condition": 7.551327766714572, "Syringe issue": 37.55296402332177, "Therapeutic product effect incomplete": 3.41657850774348, "Therapeutic response decreased": 3.349835825989292, "Wheezing": 5.744988345896746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/375.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/375.json
index 8b274e9d7ec..a77873e8886 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/375.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/375.json
@@ -1 +1 @@
-{"BK virus infection ": 149.3936424243999, "Foetal exposure during pregnancy ": 7.827990452198647, "Fungal peritonitis ": 1916.125622920623, "Live birth ": 48.0223760262891, "Off label use ": 4.999771701566923, "Peritonitis ": 41.09252560238984, "Premature baby ": 25.52749024781719, "Respiratory failure ": 8.026258961254051, "Sepsis ": 10.895298941351989, "Systemic candida ": 218.76541966221316, "Thrombocytopenia ": 2.062031435991037, "Thrombotic microangiopathy ": 112.3892235278637, "Treatment failure ": 7.548694838418296}
\ No newline at end of file
+{"Febrile neutropenia": 19.157564658482517, "Malignant neoplasm progression": 12.685740063035697, "Off label use": 2.234021553520845}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/376.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/376.json
index 739d2210fc0..13c6ea5a3cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/376.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/376.json
@@ -1 +1 @@
-{"Blood pressure increased ": 29.207727799982347}
\ No newline at end of file
+{"Hepatic function abnormal": 71.56504306676347}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/377.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/377.json
index ed6ecd2967f..510683fd812 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/377.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/377.json
@@ -1 +1 @@
-{"Anaemia ": 3.3739376790137228, "Atrial fibrillation ": 8.93195446424499, "Cardiac failure ": 10.567627143896214, "Cardiovascular disorder ": 14.125312279002154, "Coronary artery disease ": 15.759061906866531, "Cough ": 2.849929900336687, "Drug interaction ": 9.28283533907553, "Ejection fraction decreased ": 31.46523161495838, "Epistaxis ": 5.321295617415464, "Fall ": 3.4334659049482843, "Feeling cold ": 6.599960339346205, "General physical health deterioration ": 6.106721172150743, "Hyperkalaemia ": 7.934366362558093, "Hypotension ": 2.4283890132332484, "Ischaemic stroke ": 17.24953900233806, "Labelled drug-drug interaction medication error ": 21.588587890473065, "Left ventricular dysfunction ": 68.52043206096512, "Mitral valve incompetence ": 46.51361941766905, "Oedema peripheral ": 3.3669984472199115, "Peripheral coldness ": 18.66806084300031, "Product use in unapproved indication ": 2.981787376851692, "Renal impairment ": 3.998555632157141, "Syncope ": 3.1538023199180003, "Ventricular extrasystoles ": 34.48891310749317, "Ventricular tachycardia ": 26.37813993367104}
\ No newline at end of file
+{"Vomiting": 9.53444475068673}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/378.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/378.json
index 15533d481fc..7822bc42afc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/378.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/378.json
@@ -1 +1 @@
-{"Depression ": 3.063189597258597, "Drug resistance ": 8.947842229864875, "Dyspepsia ": 3.1275379498560065, "Exposure during pregnancy ": 3.3250774665221727, "Foetal exposure during pregnancy ": 3.931458941239691, "Glomerular filtration rate decreased ": 27.643554080405792, "Hyperlipidaemia ": 29.80580741826289, "Liver disorder ": 7.24168984015721, "Nightmare ": 12.394255766578366, "Renal impairment ": 2.7104834575506547, "Sleep disorder ": 10.351067834230673, "Vertigo ": 3.7775212085415726}
\ No newline at end of file
+{"Accidental overdose": 8.563238953198683, "Aggression": 11.19836694141282, "Agitation": 12.37714292818611, "Altered state of consciousness": 2.9400648935380524, "Apathy": 6.05920944286743, "Ataxia": 5.481837706584559, "Atrioventricular block": 11.995956631558204, "Atrioventricular block complete": 11.699135892539786, "Atrioventricular block second degree": 27.534798862086973, "Balance disorder": 6.028040318918639, "Behaviour disorder": 21.011946629007557, "Blood alkaline phosphatase increased": 2.568667128763497, "Blood bilirubin increased": 2.2125006369891635, "Bradycardia": 13.995962881369106, "C-reactive protein increased": 2.0664902694829395, "Cardiac failure": 3.715497680971896, "Coma": 2.5440764636835174, "Confusional state": 11.074438934625292, "Deep vein thrombosis": 3.4092784052383385, "Dehydration": 2.711074530989792, "Delirium": 4.159166451388753, "Dementia": 7.231702824859253, "Dementia Alzheimer's type": 17.77008851652304, "Depressed level of consciousness": 2.954448195420037, "Disorientation": 3.7591287089948553, "Eosinophilia": 5.388159224928923, "Epilepsy": 10.046585547440008, "Extrapyramidal disorder": 9.32988702400309, "Fall": 10.078652027351408, "Gait disturbance": 4.342012370890537, "Gamma-glutamyltransferase increased": 3.5665522441535016, "Generalised tonic-clonic seizure": 5.556787290429658, "Haemolytic anaemia": 6.088372109860061, "Hallucination": 9.62757607162916, "Hallucination, visual": 10.993170097526582, "Head discomfort": 3.262171527426476, "Hepatic cytolysis": 10.286120693337152, "Jaundice": 2.302326844018302, "Leukopenia": 3.0414971863218527, "Loss of consciousness": 2.589449812083276, "Medication error": 2.436161884917355, "Myoclonus": 10.89927844007874, "Nightmare": 3.1652504543469275, "Orthostatic hypotension": 9.311996044944376, "Pancreatitis": 2.5104449071063395, "Pancreatitis acute": 6.577299342398249, "Phlebitis": 12.852828780432867, "Product administration interrupted": 92.2203453366499, "Psychomotor hyperactivity": 6.6408419273953205, "Pulmonary embolism": 5.497713825080997, "Seizure": 5.2588201340432255, "Sinus bradycardia": 14.31911589364448, "Somnolence": 5.354912653178508, "Speech disorder": 4.3768628219594525, "Syncope": 2.847238147600123, "Transaminases increased": 3.4959936380108894, "Upper gastrointestinal haemorrhage": 5.840352509260915, "Urinary retention": 3.4123145560250343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/379.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/379.json
index df01140217c..8b1f78e9083 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/379.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/379.json
@@ -1 +1 @@
-{"Abnormal dreams ": 2.6132998755463577, "Abortion induced ": 5.908968048573806, "Abortion spontaneous ": 16.75952185738349, "Acute stress disorder ": 49.32426849592806, "Alanine aminotransferase increased ": 5.43543523959479, "Amylase increased ": 3.2901406815407586, "Aspartate aminotransferase increased ": 6.434226550716912, "Atrioventricular block complete ": 5.483628837286245, "Autoimmune hepatitis ": 24.95958915522084, "Blood HIV RNA increased ": 44.96172026973085, "Blood bilirubin increased ": 2.169721055902599, "Blood lactic acid increased ": 5.9203348935162206, "Blood triglycerides increased ": 10.750570711305576, "Bundle branch block left ": 9.554385342338607, "Cachexia ": 8.084096005892905, "Caesarean section ": 16.722194616648817, "Central nervous system lesion ": 10.886206501339606, "Cholestasis ": 2.209900875586501, "Chronic respiratory disease ": 170.11803473857734, "Cleft lip and palate ": 41.17202553950213, "Clostridium difficile colitis ": 7.609831456444077, "Conductive deafness ": 86.96421101221651, "Confusional arousal ": 421.4681794148452, "Cryptococcosis ": 77.55549317154102, "Cytomegalovirus chorioretinitis ": 28.53714859118922, "Degenerative bone disease ": 48.23030616465416, "Dilated cardiomyopathy ": 9.576896828081043, "Disseminated tuberculosis ": 31.452751516611123, "Drug abuse ": 2.585471618930736, "Drug interaction ": 3.446758208521662, "Drug level decreased ": 4.904298497000596, "Drug resistance ": 18.75058872077989, "Drug-induced liver injury ": 9.826149042804644, "Dyslipidaemia ": 18.37151561113225, "Exposure during pregnancy ": 3.893067897398778, "Fanconi syndrome ": 15.530059444042344, "Foetal exposure during pregnancy ": 7.152886455357908, "Gastritis ": 2.4523945742282023, "Gingivitis ": 8.1527815367198, "Granuloma ": 37.47050818838971, "Graves' disease ": 13.71603784859098, "Gynaecomastia ": 9.480367940897343, "HIV infection ": 96.4603203157973, "HIV viraemia ": 118.22051711534051, "Haemarthrosis ": 5.062523552540863, "Helicobacter infection ": 2.4070585561439413, "Hemiparesis ": 4.6888029409541545, "Hepatic cirrhosis ": 2.6959362093716166, "Hepatic cytolysis ": 11.49964335023513, "Hepatic failure ": 3.505591031160231, "Hepatic steatosis ": 2.7406433723046995, "Hepatitis cholestatic ": 8.67736550825753, "Hepatocellular injury ": 9.160556287000247, "Hepatomegaly ": 8.419660048653052, "Hepatosplenomegaly ": 11.98462843307787, "Hepatotoxicity ": 3.151962997086222, "Human immunodeficiency virus transmission ": 442.46612658309095, "Hydrops foetalis ": 112.44335762593488, "Hyperlactacidaemia ": 40.39872257930428, "Hyperlipidaemia ": 12.836098631899391, "Hypertriglyceridaemia ": 4.035476968333149, "Immune reconstitution inflammatory syndrome ": 236.99657015575752, "Immune reconstitution inflammatory syndrome associated tuberculosis ": 281.9161054116521, "Intentional product use issue ": 5.675337181040123, "Intracranial pressure increased ": 13.749198828075608, "Jaundice ": 2.839182166134649, "Joint stiffness ": 2.839482201355063, "Kaposi's sarcoma ": 107.17435288554265, "Labelled drug-drug interaction medication error ": 4.895999838538571, "Lactic acidosis ": 3.869819696208984, "Lipodystrophy acquired ": 56.82285513435125, "Lipohypertrophy ": 34.48858109831706, "Live birth ": 6.079738640431882, "Liver function test abnormal ": 2.119238086866003, "Liver injury ": 2.867689370019945, "Low birth weight baby ": 6.921882996301598, "Lung infiltration ": 3.808346992907371, "Lymphopenia ": 3.9351336551695297, "Maternal exposure during pregnancy ": 8.483672841340296, "Maternal exposure timing unspecified ": 10.250307255066904, "Meningitis cryptococcal ": 94.03975606283969, "Meningitis tuberculous ": 48.183797260451534, "Mental disorder ": 3.260110530908055, "Middle insomnia ": 3.973115202063137, "Mouth injury ": 28.339872014752263, "Mycobacterium avium complex infection ": 23.09017350876748, "Nasal polyps ": 9.926621125720963, "Necrosis ": 20.821467831672688, "Nephropathy toxic ": 10.862407909727676, "Nervous system disorder ": 2.9949014201624644, "Neuropsychological symptoms ": 24.485149034334952, "Neurotoxicity ": 2.437111596279093, "Normal newborn ": 18.83170393825188, "Osteopenia ": 2.1395532168954507, "Paradoxical drug reaction ": 34.394895656535255, "Paraplegia ": 10.0263513272291, "Paroxysmal extreme pain disorder ": 586.0335193128805, "Pathogen resistance ": 32.00898742464371, "Peptic ulcer ": 14.573759240115283, "Polymyalgia rheumatica ": 5.425744246544911, "Portal hypertension ": 17.512074404453557, "Post procedural hypothyroidism ": 232.15547212950776, "Pregnancy ": 12.897965922276812, "Pregnancy with implant contraceptive ": 419.6914731861493, "Premature baby ": 2.4924953161738097, "Premature delivery ": 3.4151491307965967, "Premature rupture of membranes ": 25.179919969416503, "Product substitution issue ": 2.097835031956915, "Progressive multifocal leukoencephalopathy ": 14.39666948916742, "Pulmonary tuberculosis ": 16.97020560875137, "Rash papular ": 2.0278031117796824, "Rebound effect ": 14.25731724137022, "Renal impairment ": 2.9233611371597887, "Renal tubular necrosis ": 3.957310258464496, "Retinal toxicity ": 68.61216477661677, "Rhinitis allergic ": 5.643928260125612, "Skin exfoliation ": 2.152465130373028, "Skin lesion ": 12.2005873435129, "Skin necrosis ": 7.785549729167236, "Skin ulcer ": 5.316956296796837, "Splenomegaly ": 3.8518548863923776, "Stillbirth ": 25.428185495863296, "Tachypnoea ": 2.356036853822556, "Tongue discomfort ": 5.459728999310282, "Transaminases increased ": 2.1573832644098165, "Treatment failure ": 4.467586309852562, "Treatment noncompliance ": 7.938575362057783, "Trisomy 18 ": 152.24539902521903, "Tuberculosis ": 19.47476171192955, "Tuberculosis of central nervous system ": 148.4682050411295, "Tubulointerstitial nephritis ": 4.816934084225573, "Ulcer ": 5.465337607230384, "Ultrasound antenatal screen ": 646.4873303681012, "Urinary tract inflammation ": 86.96421101221651, "Varices oesophageal ": 13.704253364061334, "Viral load increased ": 26.47656970226932, "Viral mutation identified ": 62.81485457310976, "Virologic failure ": 100.4913544220476}
\ No newline at end of file
+{"BK virus infection": 149.3936424243999, "Foetal exposure during pregnancy": 7.827990452198647, "Fungal peritonitis": 1916.125622920623, "Live birth": 48.0223760262891, "Off label use": 4.999574763249268, "Peritonitis": 41.09252560238984, "Premature baby": 25.52749024781719, "Respiratory failure": 8.02559630268252, "Sepsis": 10.895298941351989, "Systemic candida": 218.76541966221316, "Thrombocytopenia": 2.0618374827055623, "Thrombotic microangiopathy": 112.3892235278637, "Treatment failure": 7.548694838418296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/38.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/38.json
index a644182aff7..13f8a03cbde 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/38.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/38.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 8.297007844238493, "Aspartate aminotransferase increased ": 9.483824023165434, "Blood bilirubin increased ": 18.615332890126915, "Blood creatinine increased ": 8.397804156873724, "Lactic acidosis ": 18.69573347936737}
\ No newline at end of file
+{"Blood pressure increased": 6.429215857773958, "Heart rate increased": 9.13627834487562, "Infusion related reaction": 17.317630442395497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/380.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/380.json
index cad357fbcd2..e52eb62d3a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/380.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/380.json
@@ -1 +1 @@
-{"Product substitution issue ": 216.75931459080996}
\ No newline at end of file
+{"Blood pressure increased": 29.207215233523492}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/381.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/381.json
index 5958ced8765..965daf3b32e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/381.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/381.json
@@ -1 +1 @@
-{"Diarrhoea ": 3.3946369403561074, "Hypoglycaemia ": 13.731326204878052, "Lactic acidosis ": 85.40520449294411, "Vomiting ": 2.60873415525624}
\ No newline at end of file
+{"Anaemia": 3.3571296194541627, "Atrial fibrillation": 8.887210237136774, "Cardiac failure": 10.514010380271076, "Cardiovascular disorder": 14.055006195822392, "Coronary artery disease": 15.680624157626513, "Cough": 2.835706005799226, "Drug interaction": 9.511680349487788, "Ejection fraction decreased": 31.30861966909152, "Epistaxis": 5.2948025802231005, "Fall": 3.416277729656256, "Feeling cold": 6.567110249670703, "General physical health deterioration": 6.076317754053993, "Hyperkalaemia": 7.893786091363925, "Hypotension": 2.416242976186835, "Ischaemic stroke": 17.16370821805406, "Labelled drug-drug interaction medication error": 21.48113485282493, "Left ventricular dysfunction": 68.17938670480908, "Mitral valve incompetence": 46.28210752070248, "Oedema peripheral": 3.350162021500084, "Peripheral coldness": 18.575144133966177, "Product use in unapproved indication": 2.966851482688189, "Renal impairment": 3.978653550189097, "Syncope": 3.1380553100289013, "Ventricular extrasystoles": 34.31725144858339, "Ventricular tachycardia": 26.246811911367228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/382.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/382.json
index ad99f784fe9..65d2cf2b69a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/382.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/382.json
@@ -1 +1 @@
-{"Acute myocardial infarction ": 9.723389847598872, "Anaemia ": 5.0896471017655225, "Angina pectoris ": 7.759070931834747, "Angina unstable ": 30.02469311537381, "Atrial fibrillation ": 2.0732537521342174, "Blood loss anaemia ": 16.77769326125134, "Blood pressure decreased ": 2.465205843994158, "Cardiac tamponade ": 35.57768761718435, "Cerebellar haemorrhage ": 38.11089996078156, "Cerebral haematoma ": 17.185782528429502, "Cerebral haemorrhage ": 26.87872470910498, "Cerebral infarction ": 10.28740006696944, "Cholecystitis ": 8.970764776553374, "Contusion ": 2.8768384125875177, "Coronary artery restenosis ": 215.6312444510972, "Coronary artery stenosis ": 38.20466029815059, "Device occlusion ": 21.232012085761024, "Diverticulum intestinal haemorrhagic ": 98.73199944516794, "Drug eruption ": 3.514184810299948, "Drug interaction ": 2.087939270488199, "Duodenal ulcer haemorrhage ": 25.76456135924674, "Ecchymosis ": 6.930246385623509, "Eosinophilia ": 3.867433900711243, "Epistaxis ": 11.213833446579793, "Erectile dysfunction ": 3.6389916963788607, "Gastric haemorrhage ": 28.402176758269, "Gastric ulcer ": 8.857985496521357, "Gastric ulcer haemorrhage ": 35.39529556850933, "Gastrointestinal haemorrhage ": 16.383053344857686, "Gingival bleeding ": 7.418668739802642, "Haematemesis ": 4.722089718182537, "Haematochezia ": 2.631665290067257, "Haematoma ": 12.07766677869722, "Haematuria ": 5.847139049660059, "Haemoglobin decreased ": 4.137165556188809, "Haemoptysis ": 6.7696065688410485, "Haemorrhage ": 16.5862414762846, "Haemorrhage intracranial ": 17.58699624761932, "Haemorrhage subcutaneous ": 17.394324507521002, "Haemorrhagic stroke ": 11.387880975385707, "Hemiplegia ": 14.023861451095147, "Incorrect dose administered ": 4.010552341133006, "Intestinal haemorrhage ": 19.750451417370893, "Labelled drug-drug interaction medication error ": 16.698201360135137, "Liver disorder ": 2.002261408379223, "Melaena ": 21.784002915417467, "Prescribed overdose ": 3.788697294503779, "Pulmonary alveolar haemorrhage ": 61.38074092182914, "Rectal haemorrhage ": 5.9834468760417, "Retroperitoneal haematoma ": 27.170701029616268, "Retroperitoneal haemorrhage ": 28.871328669811827, "Septic shock ": 2.6366679555462884, "Shock haemorrhagic ": 34.962023022569696, "Small intestinal haemorrhage ": 46.33871289750287, "Status epilepticus ": 7.218294834511043, "Subarachnoid haemorrhage ": 16.704334966114562, "Subcutaneous haematoma ": 25.52917955779758, "Subdural haematoma ": 25.389920420506563, "Sudden death ": 11.684375460323032, "Thrombocytopenia ": 3.069053759403198, "Thrombosis in device ": 54.40024469405927, "Upper gastrointestinal haemorrhage ": 14.177910592421725, "Vascular pseudoaneurysm ": 64.32503891901919, "Vascular stent stenosis ": 346.81937805228574, "Vascular stent thrombosis ": 98.72190656238784}
\ No newline at end of file
+{"Depression": 3.063189597258597, "Drug resistance": 8.947842229864875, "Dyspepsia": 3.1275379498560065, "Exposure during pregnancy": 3.3250774665221727, "Foetal exposure during pregnancy": 3.931458941239691, "Glomerular filtration rate decreased": 27.643554080405792, "Hyperlipidaemia": 29.80580741826289, "Liver disorder": 7.24168984015721, "Nightmare": 12.394255766578366, "Renal impairment": 2.7104834575506547, "Sleep disorder": 10.351067834230673, "Vertigo": 3.7775212085415726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/383.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/383.json
index 25cd30354f8..a26d4a990ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/383.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/383.json
@@ -1 +1 @@
-{"Asthenia ": 11.8498517621964, "Herpes zoster ": 8.16818884785346, "Immunisation reaction ": 36.530906969268365, "Influenza like illness ": 2.613017390762926, "Interchange of vaccine products ": 31.434959645299845, "Vaccination site pain ": 2.883699324443119, "Vaccination site reaction ": 5.808806897481141}
\ No newline at end of file
+{"Abnormal dreams": 2.6132998755463577, "Abortion induced": 5.908968048573806, "Abortion spontaneous": 16.75952185738349, "Acute stress disorder": 49.32426849592806, "Alanine aminotransferase increased": 5.43543523959479, "Amylase increased": 3.2901406815407586, "Aspartate aminotransferase increased": 6.434226550716912, "Atrioventricular block complete": 5.483628837286245, "Autoimmune hepatitis": 24.95958915522084, "Blood HIV RNA increased": 44.96172026973085, "Blood bilirubin increased": 2.169721055902599, "Blood lactic acid increased": 5.9203348935162206, "Blood triglycerides increased": 10.750570711305576, "Bundle branch block left": 9.554385342338607, "Cachexia": 8.084096005892905, "Caesarean section": 16.722194616648817, "Central nervous system lesion": 10.886206501339606, "Cholestasis": 2.209900875586501, "Chronic respiratory disease": 170.11803473857734, "Cleft lip and palate": 41.17202553950213, "Clostridium difficile colitis": 7.609831456444077, "Conductive deafness": 86.96421101221651, "Confusional arousal": 421.4681794148452, "Cryptococcosis": 77.55549317154102, "Cytomegalovirus chorioretinitis": 28.53714859118922, "Degenerative bone disease": 48.23030616465416, "Dilated cardiomyopathy": 9.576896828081043, "Disseminated tuberculosis": 31.452751516611123, "Drug abuse": 2.585471618930736, "Drug interaction": 3.446758208521662, "Drug level decreased": 4.904298497000596, "Drug resistance": 18.75058872077989, "Drug-induced liver injury": 9.82554779370126, "Dyslipidaemia": 18.37151561113225, "Exposure during pregnancy": 3.893067897398778, "Fanconi syndrome": 15.530059444042344, "Foetal exposure during pregnancy": 7.152886455357908, "Gastritis": 2.4523945742282023, "Gingivitis": 8.1527815367198, "Granuloma": 37.47050818838971, "Graves' disease": 13.71603784859098, "Gynaecomastia": 9.480367940897343, "HIV infection": 96.4603203157973, "HIV viraemia": 118.22051711534051, "Haemarthrosis": 5.062523552540863, "Helicobacter infection": 2.4070585561439413, "Hemiparesis": 4.688211196906759, "Hepatic cirrhosis": 2.6959362093716166, "Hepatic cytolysis": 11.49964335023513, "Hepatic failure": 3.505591031160231, "Hepatic steatosis": 2.7406433723046995, "Hepatitis cholestatic": 8.67736550825753, "Hepatocellular injury": 9.157881187549656, "Hepatomegaly": 8.419660048653052, "Hepatosplenomegaly": 11.98462843307787, "Hepatotoxicity": 3.151962997086222, "Human immunodeficiency virus transmission": 442.46612658309095, "Hydrops foetalis": 112.44335762593488, "Hyperlactacidaemia": 40.39872257930428, "Hyperlipidaemia": 12.836098631899391, "Hypertriglyceridaemia": 4.035476968333149, "Immune reconstitution inflammatory syndrome": 236.99657015575752, "Immune reconstitution inflammatory syndrome associated tuberculosis": 281.9161054116521, "Intentional product use issue": 5.675337181040123, "Intracranial pressure increased": 13.749198828075608, "Jaundice": 2.839182166134649, "Joint stiffness": 2.839482201355063, "Kaposi's sarcoma": 107.17435288554265, "Labelled drug-drug interaction medication error": 4.895999838538571, "Lactic acidosis": 3.869819696208984, "Lipodystrophy acquired": 56.82285513435125, "Lipohypertrophy": 34.48858109831706, "Live birth": 6.079738640431882, "Liver function test abnormal": 2.119238086866003, "Liver injury": 2.867689370019945, "Low birth weight baby": 6.921882996301598, "Lung infiltration": 3.808346992907371, "Lymphopenia": 3.9351336551695297, "Maternal exposure during pregnancy": 8.483672841340296, "Maternal exposure timing unspecified": 10.250307255066904, "Meningitis cryptococcal": 94.03975606283969, "Meningitis tuberculous": 48.183797260451534, "Mental disorder": 3.260110530908055, "Middle insomnia": 3.973115202063137, "Mouth injury": 28.339872014752263, "Mycobacterium avium complex infection": 23.09017350876748, "Nasal polyps": 9.926621125720963, "Necrosis": 20.821467831672688, "Nephropathy toxic": 10.862407909727676, "Nervous system disorder": 2.9949014201624644, "Neuropsychological symptoms": 24.485149034334952, "Neurotoxicity": 2.437111596279093, "Normal newborn": 18.83170393825188, "Osteopenia": 2.1395532168954507, "Paradoxical drug reaction": 34.394895656535255, "Paraplegia": 10.0263513272291, "Paroxysmal extreme pain disorder": 586.0335193128805, "Pathogen resistance": 32.00898742464371, "Peptic ulcer": 14.573759240115283, "Polymyalgia rheumatica": 5.425744246544911, "Portal hypertension": 17.512074404453557, "Post procedural hypothyroidism": 232.15547212950776, "Pregnancy": 12.897965922276812, "Pregnancy with implant contraceptive": 419.6914731861493, "Premature baby": 2.4924953161738097, "Premature delivery": 3.4151491307965967, "Premature rupture of membranes": 25.179919969416503, "Product substitution issue": 2.097835031956915, "Progressive multifocal leukoencephalopathy": 14.39666948916742, "Pulmonary tuberculosis": 16.97020560875137, "Rash papular": 2.0275789840778486, "Rebound effect": 14.25731724137022, "Renal impairment": 2.9233611371597887, "Renal tubular necrosis": 3.957310258464496, "Retinal toxicity": 68.61216477661677, "Rhinitis allergic": 5.643928260125612, "Skin exfoliation": 2.152465130373028, "Skin lesion": 12.2005873435129, "Skin necrosis": 7.785549729167236, "Skin ulcer": 5.316956296796837, "Splenomegaly": 3.8518548863923776, "Stillbirth": 25.428185495863296, "Tachypnoea": 2.3557017322994294, "Tongue discomfort": 5.459728999310282, "Transaminases increased": 2.157251076664926, "Treatment failure": 4.467586309852562, "Treatment noncompliance": 7.938575362057783, "Trisomy 18": 152.24539902521903, "Tuberculosis": 19.47476171192955, "Tuberculosis of central nervous system": 148.4682050411295, "Tubulointerstitial nephritis": 4.816934084225573, "Ulcer": 5.465337607230384, "Ultrasound antenatal screen": 646.4873303681012, "Urinary tract inflammation": 86.96421101221651, "Varices oesophageal": 13.704253364061334, "Viral load increased": 26.47656970226932, "Viral mutation identified": 62.81485457310976, "Virologic failure": 100.4913544220476}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/384.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/384.json
index b471fd96b36..5a76bcaa9de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/384.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/384.json
@@ -1 +1 @@
-{"Therapy non-responder ": 381.91282480365993}
\ No newline at end of file
+{"Product substitution issue": 216.75931459080996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/385.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/385.json
index 3a29a799da2..29c0d6f69b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/385.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/385.json
@@ -1 +1 @@
-{"Cough ": 10.489308826295764, "Throat irritation ": 31.089914454059905}
\ No newline at end of file
+{"Diarrhoea": 3.3946086121909893, "Hypoglycaemia": 13.730862709173165, "Lactic acidosis": 85.40520449294411, "Vomiting": 2.6086989663837064}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/386.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/386.json
index f60eb7f5c26..496707c17cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/386.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/386.json
@@ -1 +1 @@
-{"Abdominal wall haematoma ": 7.293286651830681, "Abdominal wall haemorrhage ": 6.592813849834514, "Accident ": 3.530857527375631, "Acquired haemophilia ": 2.2248903548264574, "Activated partial thromboplastin time prolonged ": 3.0162374261426783, "Acute respiratory failure ": 2.088853876895668, "Adverse event ": 5.68256774900491, "Age-related macular degeneration ": 3.009285951837507, "Amyloidosis ": 3.873646565574226, "Anaemia ": 3.33688035760618, "Anaemia macrocytic ": 2.254918277813063, "Anal haemorrhage ": 10.029547541584476, "Aneurysm ": 4.191937442985076, "Aneurysm ruptured ": 8.138587077294591, "Angiodysplasia ": 7.797573004131726, "Anti factor X activity increased ": 115.52386320062904, "Anticoagulation drug level increased ": 9.288445782116971, "Antiphospholipid syndrome ": 7.997121519995715, "Aortic aneurysm ": 4.073779921137691, "Aortic aneurysm rupture ": 3.889108045568736, "Aortic disorder ": 9.679407215332107, "Aortic dissection ": 2.7745569954274245, "Aortic stenosis ": 3.0579891233273027, "Aortic thrombosis ": 3.102813577899986, "Aortic valve disease ": 20.85058312823719, "Aortic valve replacement ": 7.422517329871476, "Aortic valve stenosis ": 6.475274421695546, "Appendix disorder ": 3.290783196566647, "Arterial disorder ": 2.2091494959624507, "Arterial haemorrhage ": 10.049142472550706, "Arterial occlusive disease ": 2.104698133368001, "Arterial thrombosis ": 5.641196238041681, "Arteriovenous malformation ": 4.370350849036751, "Arthropathy ": 3.3169195186283607, "Aspiration pleural cavity ": 7.614443614580375, "Atheroembolism ": 12.510169212244046, "Atrial fibrillation ": 8.619192447603272, "Atrial flutter ": 3.943571338935379, "Atrial thrombosis ": 74.41860959711089, "Atrophic vulvovaginitis ": 5.380549696214997, "Back disorder ": 4.283560731257727, "Basal ganglia haemorrhage ": 41.59817321592445, "Benign prostatic hyperplasia ": 3.546436855125705, "Bladder catheterisation ": 3.259793871613891, "Bladder neoplasm ": 6.876427731048126, "Bladder operation ": 3.725319392458172, "Bladder tamponade ": 13.003589631100738, "Bleeding time prolonged ": 6.346513599081914, "Bleeding varicose vein ": 16.938764198578106, "Blood blister ": 4.001715132464055, "Blood creatinine abnormal ": 3.74005847984047, "Blood disorder ": 3.0479205858603358, "Blood iron decreased ": 3.288142790445019, "Blood loss anaemia ": 11.635155061163964, "Blood pressure diastolic abnormal ": 2.531849946363495, "Blood pressure systolic abnormal ": 2.17246954803393, "Blood test abnormal ": 3.171667260432708, "Blood urine present ": 10.853187012113892, "Blood viscosity increased ": 7.758519755910308, "Blue toe syndrome ": 3.396716618375932, "Body height decreased ": 5.262931215666815, "Bone cancer ": 2.2308208229308137, "Brain contusion ": 10.581484980839774, "Brain herniation ": 4.3666983739358765, "Brain neoplasm malignant ": 2.7893527163695637, "Brain stem haemorrhage ": 26.52218687800658, "Breast disorder ": 2.585098252771314, "Breast haematoma ": 7.623431057954024, "Breast haemorrhage ": 8.581724377887467, "Bronchial haemorrhage ": 6.169749691736408, "Bronchial secretion retention ": 4.551385417220312, "Bronchial wall thickening ": 5.157981976522295, "COVID-19 pneumonia ": 2.326858853898657, "Calculus bladder ": 5.909672674219296, "Cancer surgery ": 3.3417155198641377, "Cardiac ablation ": 18.2849970108985, "Cardiac amyloidosis ": 5.498799956298751, "Cardiac disorder ": 10.864253896064886, "Cardiac failure ": 3.131069201716865, "Cardiac failure acute ": 2.725192913895552, "Cardiac failure chronic ": 3.017735585212816, "Cardiac failure congestive ": 3.188745472850586, "Cardiac fibrillation ": 4.022691021758137, "Cardiac flutter ": 2.191255687269185, "Cardiac pacemaker insertion ": 11.066822507884291, "Cardiac tamponade ": 6.629846756264094, "Cardiac valve disease ": 13.090848354012389, "Cardiac ventricular thrombosis ": 13.482786689681452, "Cardioversion ": 30.37698521905501, "Carotid arteriosclerosis ": 2.514351555136754, "Carotid artery disease ": 4.375704885111605, "Carotid artery occlusion ": 2.297783335098017, "Carotid artery stenosis ": 3.1535009726382546, "Carpal tunnel syndrome ": 4.060750994182974, "Cataract ": 2.570693854505259, "Catheter placement ": 3.1776154255171325, "Catheter site haemorrhage ": 7.475241684036214, "Catheterisation cardiac ": 2.246324974374478, "Cell death ": 2.001161259931424, "Cerebellar haematoma ": 17.679380060402934, "Cerebellar haemorrhage ": 30.256845225856573, "Cerebellar infarction ": 5.906671324338264, "Cerebral amyloid angiopathy ": 6.849158639178266, "Cerebral artery embolism ": 20.343399673502446, "Cerebral artery occlusion ": 3.0181532396157995, "Cerebral haematoma ": 27.025039422845364, "Cerebral haemorrhage ": 24.782486016188862, "Cerebral infarction ": 13.78564970797908, "Cerebral ischaemia ": 3.2106964201826576, "Cerebral mass effect ": 10.679118677352198, "Cerebral microhaemorrhage ": 7.738648184013976, "Cerebral small vessel ischaemic disease ": 2.846693043746406, "Cerebral thrombosis ": 3.254039370289824, "Cerebral ventricular rupture ": 60.58876673469882, "Cerebrovascular accident ": 10.303969557837297, "Cerebrovascular disorder ": 2.1666553019584005, "Cervical vertebral fracture ": 4.371814168631916, "Cholestatic liver injury ": 2.4255276601571154, "Chronic left ventricular failure ": 10.640130447044134, "Circumstance or information capable of leading to medication error ": 5.050222890493761, "Coagulation factor V level abnormal ": 15.08833991582244, "Colon cancer ": 4.291847697780801, "Colon neoplasm ": 4.714050053360888, "Compartment syndrome ": 3.5677503490303475, "Conjunctival haemorrhage ": 8.348533677429831, "Contusion ": 4.314768878041203, "Craniocerebral injury ": 2.15538603184477, "Craniofacial fracture ": 2.3928531506801227, "Craniotomy ": 33.93874012961033, "Creatinine renal clearance abnormal ": 9.627683228623953, "Cutaneous vasculitis ": 2.325476273167107, "Death ": 2.146146171531744, "Deep vein thrombosis ": 6.079256972686195, "Dementia ": 6.967471757484527, "Dementia Alzheimer's type ": 5.524412585524457, "Dental care ": 5.710555313068394, "Dental operation ": 4.457816363781606, "Device related thrombosis ": 3.197149907745068, "Diastolic dysfunction ": 2.8708311437213574, "Dieulafoy's vascular malformation ": 10.919531897994723, "Diverticulitis intestinal haemorrhagic ": 14.210089769804812, "Diverticulum ": 2.240109254684085, "Diverticulum intestinal haemorrhagic ": 33.00622663968115, "Duodenal ulcer ": 3.8330296984956895, "Duodenal ulcer haemorrhage ": 5.812450062267315, "Dyschezia ": 2.2880939456429297, "Ear congestion ": 2.247412164230413, "Ear haemorrhage ": 12.704485505650254, "Ecchymosis ": 2.61792284215252, "Ejection fraction ": 3.968887028947694, "Ejection fraction abnormal ": 6.503314460189596, "Elephantiasis ": 36.11920507529975, "Embolic cerebral infarction ": 12.265326190051605, "Embolic stroke ": 48.89697717426432, "Embolism ": 5.629646065321832, "Embolism arterial ": 4.461745988823241, "Embolism venous ": 10.94544583467757, "Endocarditis noninfective ": 21.841272133949232, "Epidural haemorrhage ": 17.191654366998073, "Epistaxis ": 10.054806126937931, "Essential hypertension ": 2.7015006697822392, "Extradural haematoma ": 13.029187238033831, "Eye contusion ": 3.0756714839623074, "Eye disorder ": 2.486244237740256, "Eye haematoma ": 4.417189613743751, "Eye haemorrhage ": 11.313018125307648, "Face injury ": 2.129853767681076, "Faeces discoloured ": 6.109531738890694, "Failure to suspend medication ": 159.78187428899716, "Fall ": 4.548622959575362, "Femoral neck fracture ": 2.570256929898922, "Femur fracture ": 2.068177423261455, "Food interaction ": 2.106821336923653, "Foreign body ": 6.773449635607992, "Gallbladder disorder ": 3.4842369177734325, "Gamma-glutamyltransferase abnormal ": 3.933919987423834, "Gastric antral vascular ectasia ": 5.442689839722771, "Gastric haemorrhage ": 11.68614236482202, "Gastric ulcer ": 3.9705309077916944, "Gastric ulcer haemorrhage ": 8.478055216677836, "Gastritis erosive ": 2.71242916780463, "Gastritis haemorrhagic ": 4.746200922300627, "Gastrointestinal angiodysplasia ": 8.310503277044662, "Gastrointestinal haemorrhage ": 18.527345941885574, "Gastrointestinal polyp ": 18.791516240245475, "Gastrointestinal polyp haemorrhage ": 16.839176470809043, "Gastrointestinal tube insertion ": 6.065023838259913, "Gastrointestinal ulcer haemorrhage ": 17.486244908525382, "Gastrointestinal vascular malformation haemorrhagic ": 7.456898994754625, "Gastrostomy ": 5.708181425065748, "Genital haemorrhage ": 4.263292680672584, "Gingival bleeding ": 8.81681994686775, "Glioblastoma ": 2.32722122478057, "Gout ": 2.4274453535780136, "Haemarthrosis ": 8.364239985396967, "Haematemesis ": 5.286726837040084, "Haematochezia ": 6.178089556178612, "Haematoma ": 9.631491425366338, "Haematoma evacuation ": 34.913481656251, "Haematoma muscle ": 12.607735570857788, "Haematospermia ": 3.9188670101785488, "Haematuria ": 10.86217903547569, "Haemobilia ": 9.057287006545344, "Haemoglobin abnormal ": 2.817907864919251, "Haemoglobin decreased ": 3.931341972396147, "Haemoperitoneum ": 6.185539797605499, "Haemoptysis ": 6.262239185797077, "Haemorrhage ": 17.798524805912308, "Haemorrhage intracranial ": 32.474074870565154, "Haemorrhage subcutaneous ": 27.84313481040556, "Haemorrhage urinary tract ": 14.868732934547223, "Haemorrhagic cerebral infarction ": 27.942138335375837, "Haemorrhagic diathesis ": 10.86553708568885, "Haemorrhagic disorder ": 13.454808682038507, "Haemorrhagic hepatic cyst ": 42.25727010196169, "Haemorrhagic infarction ": 23.964531344603422, "Haemorrhagic stroke ": 23.605829252793217, "Haemorrhagic transformation stroke ": 16.532783812562613, "Haemorrhoidal haemorrhage ": 20.2293577897148, "Haemorrhoids ": 2.844159977369024, "Haemostasis ": 31.158359845470763, "Haemothorax ": 11.743825285805633, "Head injury ": 5.419359569605819, "Heart valve incompetence ": 4.297966259728445, "Heart valve replacement ": 7.882346610854357, "Helicobacter test positive ": 2.877076278470465, "Hemiparesis ": 2.3362342165037644, "Hemiplegia ": 2.4879808466369853, "Hepatic haemorrhage ": 7.110144150968395, "Hernia ": 3.568909457307575, "High frequency ablation ": 57.879488600570006, "Hip fracture ": 4.269053421002841, "Hospitalisation ": 4.297572012549787, "Hydrocephalus ": 2.1295312568348383, "Hypercoagulation ": 4.321149540026172, "Hypoacusis ": 2.0059797098908456, "Hypovolaemic shock ": 2.744189813199186, "Idiopathic interstitial pneumonia ": 9.396406832254192, "Implant site haemorrhage ": 15.21130207721149, "Inability to afford medication ": 2.6179181648591188, "Incision site haemorrhage ": 14.804861072022629, "Increased tendency to bruise ": 3.824710492078796, "Infarction ": 4.044953239724482, "Infrequent bowel movements ": 2.1000561080311195, "Infusion site haemorrhage ": 11.553040939302468, "Inguinal hernia ": 2.6250916000960345, "Intentional product use issue ": 12.30260033786641, "Intentional underdose ": 3.2489984699311987, "Internal haemorrhage ": 35.661988071516724, "International normalised ratio abnormal ": 3.566632118801942, "International normalised ratio fluctuation ": 3.6049734275225735, "Intestinal haemorrhage ": 13.467533117786372, "Intestinal polyp ": 3.3087692493811622, "Intra-abdominal haematoma ": 3.622259578048948, "Intra-abdominal haemorrhage ": 9.44721658955165, "Intracranial aneurysm ": 4.286797686934121, "Intracranial haematoma ": 14.808275286788692, "Intraventricular haemorrhage ": 18.22659708926494, "Iron deficiency anaemia ": 5.350726431493227, "Ischaemia ": 2.076278699212947, "Ischaemic cerebral infarction ": 4.971902340279449, "Ischaemic stroke ": 14.237270524511388, "Joint injury ": 2.045641108151069, "Labelled drug-drug interaction medication error ": 3.0008960257388377, "Lacunar infarction ": 2.077785978298765, "Laparotomy ": 2.677067177231682, "Large intestinal haemorrhage ": 18.398287938529457, "Large intestine polyp ": 3.26668915874244, "Laryngeal haemorrhage ": 18.36423744601053, "Limb injury ": 3.268037144614117, "Limb mass ": 2.7097724360430706, "Loose tooth ": 2.203686274414696, "Lower gastrointestinal haemorrhage ": 16.645373803810696, "Lower limb fracture ": 2.214796992671167, "Lung cancer metastatic ": 4.466800069677869, "Lung carcinoma cell type unspecified stage IV ": 4.785078586457598, "Lung neoplasm malignant ": 2.7448782764379063, "Macular degeneration ": 2.644889694056368, "Mallory-Weiss syndrome ": 4.41867178875727, "Melaena ": 12.89642416117359, "Meningorrhagia ": 10.418608019474334, "Meniscus injury ": 2.5984031762032744, "Mesothelioma ": 12.511508345070762, "Microcytic anaemia ": 4.40117027565731, "Middle cerebral artery stroke ": 12.256099977060725, "Mineral supplementation ": 9.854581840918367, "Mitral valve disease ": 10.502652934576904, "Mitral valve incompetence ": 2.535094015418429, "Mitral valve stenosis ": 4.69058633009984, "Mixed liver injury ": 2.578424413578431, "Mouth haemorrhage ": 7.591971987547864, "Muscle haemorrhage ": 13.860986286403415, "Muscle rupture ": 2.366332459798268, "N-terminal prohormone brain natriuretic peptide increased ": 3.2214260905396137, "Neoplasm ": 2.680417327949972, "Neoplasm malignant ": 5.24066595545308, "Neovascular age-related macular degeneration ": 4.136404561931448, "Nephrectomy ": 4.948545414892426, "Neurologic neglect syndrome ": 3.0974762050922178, "No adverse event ": 4.334242680302658, "Obstruction ": 3.5526240057503102, "Occult blood ": 18.33089033289348, "Occult blood positive ": 5.931428761155782, "Oesophageal disorder ": 2.9281528325634967, "Oesophageal haemorrhage ": 7.472711899787304, "Oesophageal ulcer haemorrhage ": 5.317679950065124, "Ophthalmic vein thrombosis ": 3.165873003655279, "Ovarian vein thrombosis ": 26.51688724578051, "Paraplegia ": 2.450934675190487, "Pelvic fracture ": 2.14136273154322, "Pelvic haematoma ": 8.44189979001699, "Pelvic venous thrombosis ": 2.2388169361472903, "Penile haemorrhage ": 8.350988172112316, "Peptic ulcer ": 2.7015006697822392, "Peptic ulcer haemorrhage ": 4.346921126301893, "Percutaneous coronary intervention ": 15.628145133870683, "Pericardial drainage ": 12.970036131262283, "Pericardial haemorrhage ": 25.05009917101124, "Periorbital haematoma ": 11.159269012890167, "Peripheral arterial occlusive disease ": 2.7651290733313423, "Peripheral artery occlusion ": 2.096004366600632, "Peripheral artery thrombosis ": 3.649051938326524, "Peripheral embolism ": 6.739992436345964, "Petechiae ": 2.1587102200507315, "Pharyngeal haemorrhage ": 13.014032694093794, "Platelet transfusion ": 2.6949095395854026, "Polycystic ovaries ": 10.078486062131432, "Polyp ": 5.673721214840196, "Polypectomy ": 13.864676096176977, "Post procedural haematoma ": 14.607861096484418, "Post procedural haematuria ": 32.98303914682567, "Post procedural haemorrhage ": 24.00538431564614, "Post procedural infection ": 2.4896543912600486, "Postoperative thrombosis ": 14.262714572506985, "Prescribed overdose ": 4.478169672840556, "Prescribed underdose ": 55.06955722708253, "Procedural haemorrhage ": 19.312829696576863, "Product blister packaging issue ": 4.029400366951027, "Product label issue ": 3.4804982310872354, "Product packaging quantity issue ": 5.091454360551792, "Product prescribing error ": 2.323487921278806, "Prostatic disorder ": 8.282018900741669, "Prostatic haemorrhage ": 22.28347239732169, "Prostatic operation ": 7.162743490236901, "Prostatomegaly ": 2.423047796323768, "Prothrombin time ratio increased ": 6.149256689058482, "Prothrombin time shortened ": 3.1047072311038444, "Pulmonary alveolar haemorrhage ": 7.392505885164575, "Pulmonary embolism ": 5.046316190752374, "Pulmonary haemorrhage ": 5.989129532778697, "Pulmonary sepsis ": 3.946128878443052, "Pulmonary thrombosis ": 7.269941104295416, "Pulpitis dental ": 3.1498690574462844, "Puncture site haemorrhage ": 6.5223287080144505, "Purpura ": 2.1583919059620293, "Putamen haemorrhage ": 40.70555012857368, "Rectal cancer ": 3.4518961855279464, "Rectal haemorrhage ": 10.785926597124416, "Rectal ulcer haemorrhage ": 12.145510667586628, "Red blood cell transfusion ": 29.079301342660955, "Renal disorder ": 3.790555560394984, "Renal function test abnormal ": 2.2595473778868884, "Renal haematoma ": 6.94316828208914, "Renal haemorrhage ": 16.144603610326744, "Renal impairment ": 2.719072584125228, "Renal infarct ": 4.134741684747003, "Retinal haemorrhage ": 4.072032575720949, "Retroperitoneal haematoma ": 6.36052257700616, "Retroperitoneal haemorrhage ": 5.047299853825314, "Rhinitis allergic ": 3.077997175193168, "Scleral haemorrhage ": 12.977926372590542, "Scratch ": 2.570183969435943, "Seborrhoeic keratosis ": 2.9486444982725044, "Senile dementia ": 5.744455454513274, "Sensitisation ": 9.416322588777582, "Shock haemorrhagic ": 11.31341028150465, "Single functional kidney ": 7.744050743390675, "Sinus node dysfunction ": 2.04756402481731, "Skin cancer ": 2.2377037970151403, "Skin haemorrhage ": 6.655293447088898, "Skin laceration ": 7.685870144808694, "Skull fracture ": 3.237891432385267, "Sleep apnoea syndrome ": 2.977148651437226, "Small intestinal haemorrhage ": 12.762960317976765, "Soft tissue haemorrhage ": 7.846142889654954, "Spinal cord haematoma ": 9.835001037496006, "Spinal cord haemorrhage ": 32.358945230425725, "Spinal disorder ": 3.9220149930677817, "Spinal epidural haematoma ": 4.989587882126978, "Splenic haemorrhage ": 15.90512194039946, "Splenic rupture ": 2.7864925027583625, "Spontaneous haematoma ": 7.958096271270964, "Spontaneous haemorrhage ": 17.844688464183093, "Stent placement ": 3.53926434615937, "Stoma site haemorrhage ": 9.091236336200415, "Stress fracture ": 2.894468028928482, "Subarachnoid haemorrhage ": 13.096167844270582, "Subcapsular renal haematoma ": 8.440257728738448, "Subcutaneous haematoma ": 7.735414207091756, "Subdural haematoma ": 19.38551091233124, "Subdural haemorrhage ": 15.214601432025654, "Surgery ": 6.009813090301468, "Tachyarrhythmia ": 2.4097213627170437, "Thalamic infarction ": 3.595917180351547, "Thalamus haemorrhage ": 53.66809023908258, "Throat cancer ": 2.149237577734681, "Thrombectomy ": 22.09944585424404, "Thrombosis ": 9.98676141062094, "Thrombotic stroke ": 6.0205948439706285, "Tongue haemorrhage ": 3.757013504805918, "Tongue neoplasm malignant stage unspecified ": 2.584740837872284, "Tooth disorder ": 19.487095391863605, "Tooth extraction ": 4.15772237659085, "Tooth fracture ": 2.1749403755582746, "Transfusion ": 21.28666246514373, "Transient ischaemic attack ": 7.192627051920292, "Traumatic fracture ": 9.325613116241495, "Traumatic haematoma ": 16.849723981364953, "Traumatic haemorrhage ": 30.623982985903854, "Traumatic haemothorax ": 16.538672437917782, "Traumatic intracranial haemorrhage ": 33.0706713745353, "Traumatic lung injury ": 2.642901775686463, "Treatment noncompliance ": 5.873318441099286, "Tumour haemorrhage ": 8.457901856553727, "Ulcer ": 2.1132407000417364, "Ulcer haemorrhage ": 4.852543782694105, "Upper gastrointestinal haemorrhage ": 7.755502830533035, "Urethral haemorrhage ": 16.399142436691708, "Urinary bladder haemorrhage ": 33.31290169044828, "Urogenital haemorrhage ": 13.78863235625374, "Uterine disorder ": 6.6627138568353725, "Uterine haemorrhage ": 2.8074527204748803, "Vaginal haemorrhage ": 2.139822364305374, "Varicose vein ": 3.8188055604719646, "Vascular cauterisation ": 42.25727010196169, "Vascular occlusion ": 2.5828577298352, "Vascular pseudoaneurysm ": 3.310441291262918, "Vascular purpura ": 3.423264069837594, "Vascular rupture ": 3.6853321938930974, "Vein disorder ": 2.595433906201764, "Vein rupture ": 4.854529351873127, "Vena cava thrombosis ": 2.5274133666166225, "Venous haemorrhage ": 7.08937327381996, "Venous thrombosis ": 2.6543583594522384, "Ventricular drainage ": 50.95462680899003, "Vitreous haemorrhage ": 5.618321305395564, "Weight abnormal ": 3.867949920595654, "Weight fluctuation ": 4.857622923340889, "Wound haemorrhage ": 26.669319047637, "Wrong dose ": 2.002012907756609, "Wrong patient received product ": 3.717334093272944, "Wrong technique in product usage process ": 2.305527318333674}
\ No newline at end of file
+{"Acute myocardial infarction": 9.723389847598872, "Anaemia": 5.0896471017655225, "Angina pectoris": 7.759070931834747, "Angina unstable": 30.02469311537381, "Atrial fibrillation": 2.073197154401347, "Blood loss anaemia": 16.77769326125134, "Blood pressure decreased": 2.465125824048433, "Cardiac tamponade": 35.57768761718435, "Cerebellar haemorrhage": 38.11089996078156, "Cerebral haematoma": 17.185782528429502, "Cerebral haemorrhage": 26.87872470910498, "Cerebral infarction": 10.28740006696944, "Cholecystitis": 8.970764776553374, "Contusion": 2.8768384125875177, "Coronary artery restenosis": 215.6312444510972, "Coronary artery stenosis": 38.20466029815059, "Device occlusion": 21.232012085761024, "Diverticulum intestinal haemorrhagic": 98.73199944516794, "Drug eruption": 3.514184810299948, "Drug interaction": 2.087939270488199, "Duodenal ulcer haemorrhage": 25.76456135924674, "Ecchymosis": 6.930246385623509, "Eosinophilia": 3.867433900711243, "Epistaxis": 11.213833446579793, "Erectile dysfunction": 3.6389916963788607, "Gastric haemorrhage": 28.402176758269, "Gastric ulcer": 8.852091763668387, "Gastric ulcer haemorrhage": 35.39529556850933, "Gastrointestinal haemorrhage": 16.383053344857686, "Gingival bleeding": 7.418668739802642, "Haematemesis": 4.721670751530465, "Haematochezia": 2.631405035802383, "Haematoma": 12.07766677869722, "Haematuria": 5.847139049660059, "Haemoglobin decreased": 4.137165556188809, "Haemoptysis": 6.7696065688410485, "Haemorrhage": 16.5862414762846, "Haemorrhage intracranial": 17.58699624761932, "Haemorrhage subcutaneous": 17.394324507521002, "Haemorrhagic stroke": 11.387880975385707, "Hemiplegia": 14.023861451095147, "Incorrect dose administered": 4.010552341133006, "Intestinal haemorrhage": 19.750451417370893, "Labelled drug-drug interaction medication error": 16.698201360135137, "Liver disorder": 2.002261408379223, "Melaena": 21.78118432442854, "Prescribed overdose": 3.788697294503779, "Pulmonary alveolar haemorrhage": 61.38074092182914, "Rectal haemorrhage": 5.9834468760417, "Retroperitoneal haematoma": 27.170701029616268, "Retroperitoneal haemorrhage": 28.871328669811827, "Septic shock": 2.6366679555462884, "Shock haemorrhagic": 34.962023022569696, "Small intestinal haemorrhage": 46.33871289750287, "Status epilepticus": 7.218294834511043, "Subarachnoid haemorrhage": 16.704334966114562, "Subcutaneous haematoma": 25.52917955779758, "Subdural haematoma": 25.389920420506563, "Sudden death": 11.684375460323032, "Thrombocytopenia": 3.0687649423840355, "Thrombosis in device": 54.40024469405927, "Upper gastrointestinal haemorrhage": 14.17405371057757, "Vascular pseudoaneurysm": 64.32503891901919, "Vascular stent stenosis": 346.81937805228574, "Vascular stent thrombosis": 98.72190656238784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/387.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/387.json
index 49431d3fb83..d5f464d9626 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/387.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/387.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.9974849293112027, "Abdominal distension ": 6.230438585629753, "Abdominal pain ": 6.274121313703742, "Abdominal pain lower ": 29.46956243178612, "Abdominal pain upper ": 3.0368345967082138, "Abortion induced ": 131.69229441514122, "Abortion spontaneous ": 11.008724546845963, "Acne ": 8.076129688567814, "Adnexa uteri pain ": 43.08668577799354, "Amenorrhoea ": 2.275766905749496, "Appetite disorder ": 9.00152179985779, "Back pain ": 2.480527595472175, "Breast discomfort ": 58.53795787571606, "Breast pain ": 21.78240385878443, "Breast swelling ": 24.15111959547352, "Breast tenderness ": 35.05443348359041, "Depressed mood ": 2.4627070456965297, "Diarrhoea ": 2.8705250141867067, "Disturbance in attention ": 2.3586285730297303, "Drug ineffective ": 4.230885789253019, "Dry mouth ": 2.5397258692379583, "Dysmenorrhoea ": 4.680213937965393, "Ectopic pregnancy ": 92.73931409255113, "Emotional disorder ": 4.808722830383373, "Exposure during pregnancy ": 2.68154424489079, "Exposure via breast milk ": 6.543293460583357, "Flatulence ": 3.811313689249257, "Heavy menstrual bleeding ": 4.733054172327333, "Hot flush ": 4.228055623300692, "Hypomenorrhoea ": 59.68453358266352, "Inappropriate schedule of product administration ": 6.445725806671893, "Increased appetite ": 5.277451658542609, "Intermenstrual bleeding ": 6.011288323229672, "Labelled drug-drug interaction medication error ": 5.507525391582116, "Menstrual disorder ": 2.977724608827629, "Menstruation delayed ": 84.35303207001584, "Menstruation irregular ": 2.1522009742812838, "Mood altered ": 3.743010773041569, "Mood swings ": 19.94721924100916, "Nausea ": 2.1544969582757045, "Panic attack ": 2.076656878830349, "Pelvic pain ": 24.28188440744931, "Polymenorrhoea ": 14.503021723401998, "Pregnancy ": 29.27504305039617, "Pregnancy after post coital contraception ": 7627.940313052155, "Pruritus genital ": 17.2964921881521, "Thirst ": 2.9726951049976704, "Unintended pregnancy ": 1534.5004909373415, "Vaginal discharge ": 95.53899126990868, "Vaginal haemorrhage ": 85.60030502460712, "Vulvovaginal pruritus ": 22.795403911648453}
\ No newline at end of file
+{"Asthenia": 9.00844791303468, "Herpes zoster": 6.217454033881553, "Immunisation reaction": 27.80279477065455, "Influenza like illness": 2.4025247631602227, "Interchange of vaccine products": 24.492341929467337, "Vaccination site pain": 2.397686094985078, "Vaccination site reaction": 4.423278918838049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/388.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/388.json
index ba782830dd0..109c40946e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/388.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/388.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.0693782950609045, "Alopecia ": 5.955642799865957, "Micturition urgency ": 80.6509196419714, "Off label use ": 2.1610161963722967}
\ No newline at end of file
+{"Therapy non-responder": 381.87945830588967}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/389.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/389.json
index 486e0302808..caae5c27183 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/389.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/389.json
@@ -1 +1 @@
-{"Anti factor VIII antibody positive ": 1392.4633636192832, "Factor VIII inhibition ": 1020.4188000615862, "Haemarthrosis ": 389.0320415415492, "Haemorrhage ": 19.04951723366358, "Off label use ": 7.116804992056213}
\ No newline at end of file
+{"Cough": 10.489211536193682, "Throat irritation": 31.089914454059905}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/39.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/39.json
index 24db720f730..d47951c56a6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/39.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/39.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.7221421031876054, "Anhedonia ": 8.890327335125598, "Anxiety ": 3.07090957720799, "Condition aggravated ": 3.023400683919979, "Depression ": 7.246560925543954, "Drug ineffective ": 3.684046978129013, "Drug interaction ": 4.938149239229934, "Drug intolerance ": 4.066895885148028, "Dry mouth ": 5.464969975574975, "Electrocardiogram QT prolonged ": 7.206060387942967, "Extrapyramidal disorder ": 34.82692629723762, "Hepatic enzyme increased ": 4.059472798678062, "Hyperhidrosis ": 3.735703102688356, "Hyponatraemia ": 11.996810438920177, "Off label use ": 2.166901394186165, "Overdose ": 2.7657241129280954, "Product use in unapproved indication ": 3.321710721425925, "Sedation complication ": 50.73090015381563, "Sleep disorder ": 5.576274140013453, "Suicidal ideation ": 9.64852572009864, "Suicide attempt ": 4.243832930264444, "Tachycardia ": 5.768584291247288, "Therapy non-responder ": 17.17513717426437, "Type 2 diabetes mellitus ": 20.76083486774135, "Vertigo ": 4.40874978521634, "Weight decreased ": 2.26619573459899, "Weight increased ": 4.625625762765139}
\ No newline at end of file
+{"Alanine aminotransferase increased": 8.297007844238493, "Aspartate aminotransferase increased": 9.483824023165434, "Blood bilirubin increased": 18.615332890126915, "Blood creatinine increased": 8.397804156873724, "Lactic acidosis": 18.69573347936737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/390.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/390.json
index f4f462d84a3..1fbfe3ba1ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/390.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/390.json
@@ -1 +1 @@
-{"Ovarian hyperstimulation syndrome ": 1163.225652223502}
\ No newline at end of file
+{"Abdominal wall haematoma": 7.290085562780676, "Abdominal wall haemorrhage": 6.589920302667124, "Accident": 3.5293078100237545, "Acquired haemophilia": 2.2239138630742104, "Activated partial thromboplastin time prolonged": 3.0149135841013583, "Acute respiratory failure": 2.087937057208325, "Adverse event": 5.680073406066571, "Age-related macular degeneration": 3.00796519342737, "Amyloidosis": 3.8719464356423754, "Anaemia": 3.3354154641044724, "Anaemia macrocytic": 2.253928599965841, "Anal haemorrhage": 10.025145494913934, "Aneurysm": 4.1900975833659215, "Aneurysm ruptured": 8.135015066755319, "Angiodysplasia": 7.794150695718074, "Anti factor X activity increased": 115.4731606411558, "Anticoagulation drug level increased": 9.284369146163844, "Antiphospholipid syndrome": 7.993611566290993, "Aortic aneurysm": 4.071991919971926, "Aortic aneurysm rupture": 3.8874011384393983, "Aortic disorder": 9.675158963182872, "Aortic dissection": 2.773339246012965, "Aortic stenosis": 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2.583606410798398, "Tooth disorder": 19.478541744647742, "Tooth extraction": 4.15589753551496, "Tooth fracture": 2.1739857829467994, "Transfusion": 21.277319007104893, "Transient ischaemic attack": 7.189469854020823, "Traumatic fracture": 9.321520151281506, "Traumatic haematoma": 17.217695612954767, "Traumatic haemorrhage": 30.610541926250917, "Traumatic haemothorax": 16.531413688035972, "Traumatic intracranial haemorrhage": 33.0561564087775, "Traumatic lung injury": 2.6417418167355518, "Treatment noncompliance": 5.870740415546925, "Tumour haemorrhage": 8.454189622179612, "Ulcer": 2.112313187727061, "Ulcer haemorrhage": 4.850413952084125, "Upper gastrointestinal haemorrhage": 7.749881910531191, "Urethral haemorrhage": 16.39194486927251, "Urinary bladder haemorrhage": 33.2982801273963, "Urogenital haemorrhage": 13.782580593129104, "Uterine disorder": 6.65978960048534, "Uterine haemorrhage": 2.8062205198555747, "Vaginal haemorrhage": 2.138883144169996, "Varicose vein": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/391.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/391.json
index 878d0fa1f59..c574e0cfde8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/391.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/391.json
@@ -1 +1 @@
-{"Anaemia ": 2.634889364068919, "Bone marrow failure ": 44.31260794340105, "Cachexia ": 109.45748141842796, "Drug ineffective ": 3.052824225247063, "Gingival bleeding ": 23.818822589702226, "Haemoglobin decreased ": 5.949878964008663, "Multiple-drug resistance ": 75.24112928101874, "Off label use ": 2.0459434922452813, "Pancytopenia ": 17.374029516055028, "Platelet count decreased ": 19.06171910274545, "Product use in unapproved indication ": 15.022074387940744, "Refractoriness to platelet transfusion ": 3238.828939406906, "Thrombocytopenia ": 4.886991627450409, "White blood cell count decreased ": 3.109382470609565}
\ No newline at end of file
+{"Abdominal discomfort": 2.9974849293112027, "Abdominal distension": 6.230438585629753, "Abdominal pain": 6.274121313703742, "Abdominal pain lower": 29.46956243178612, "Abdominal pain upper": 3.0368345967082138, "Abortion induced": 131.69229441514122, "Abortion spontaneous": 11.008724546845963, "Acne": 8.076129688567814, "Adnexa uteri pain": 43.08668577799354, "Amenorrhoea": 2.275766905749496, "Appetite disorder": 9.00152179985779, "Back pain": 2.480527595472175, "Breast discomfort": 58.53795787571606, "Breast pain": 21.78240385878443, "Breast swelling": 24.15111959547352, "Breast tenderness": 35.05443348359041, "Depressed mood": 2.4627070456965297, "Diarrhoea": 2.8705010408656464, "Disturbance in attention": 2.3586285730297303, "Drug ineffective": 4.2308544785552185, "Dry mouth": 2.5397258692379583, "Dysmenorrhoea": 4.680213937965393, "Ectopic pregnancy": 92.73931409255113, "Emotional disorder": 4.808722830383373, "Exposure during pregnancy": 2.68154424489079, "Exposure via breast milk": 6.543293460583357, "Flatulence": 3.8110036848793216, "Heavy menstrual bleeding": 4.733054172327333, "Hot flush": 4.228055623300692, "Hypomenorrhoea": 59.68453358266352, "Inappropriate schedule of product administration": 6.445725806671893, "Increased appetite": 5.277451658542609, "Intermenstrual bleeding": 6.011288323229672, "Labelled drug-drug interaction medication error": 5.507525391582116, "Menstrual disorder": 2.977724608827629, "Menstruation delayed": 84.35303207001584, "Menstruation irregular": 2.1522009742812838, "Mood altered": 3.743010773041569, "Mood swings": 19.94721924100916, "Nausea": 2.1544871205938207, "Panic attack": 2.076656878830349, "Pelvic pain": 24.28188440744931, "Polymenorrhoea": 14.503021723401998, "Pregnancy": 29.27504305039617, "Pregnancy after post coital contraception": 7627.940313052155, "Pruritus genital": 17.2964921881521, "Thirst": 2.9726951049976704, "Unintended pregnancy": 1534.5004909373415, "Vaginal discharge": 95.53899126990868, "Vaginal haemorrhage": 85.60030502460712, "Vulvovaginal pruritus": 22.795403911648453}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/392.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/392.json
index b208ea966c5..7cbb645a1a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/392.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/392.json
@@ -1 +1 @@
-{"Adverse event ": 6.811978961626962, "Alanine aminotransferase increased ": 2.2303891107413003, "Anaphylactic reaction ": 5.030237175374499, "Anaphylactic shock ": 2.1454589944833344, "Aspartate aminotransferase increased ": 2.316588152999061, "Aspiration ": 8.572635537133758, "Blood albumin decreased ": 11.072762026873674, "Blood chloride decreased ": 33.369018037201094, "Blood magnesium decreased ": 14.809533992840915, "Blood sodium decreased ": 4.766771884988119, "Blood urea decreased ": 52.37347235055133, "Blood urea increased ": 2.7560912039608323, "Bone marrow failure ": 8.81581645064908, "Bronchopulmonary aspergillosis ": 12.45973788943276, "Cholestasis ": 4.9458198199253, "Congenital aplasia ": 27.7043105783278, "Constipation ": 2.148383724398482, "Death ": 2.8770921260801754, "Dermatitis bullous ": 21.364570214093018, "Dermatitis exfoliative generalised ": 6.2066133312875165, "Dermatitis infected ": 188.61368844580625, "Drug eruption ": 3.061240749645224, "Drug interaction ": 2.641515649050951, "Dysphagia ": 4.705210760438708, "Encephalopathy ": 35.7531092545134, "Erythema ": 4.53597422504212, "Febrile bone marrow aplasia ": 80.07372076413918, "Flushing ": 4.939116509783689, "Graft versus host disease ": 10.95782757742808, "Hepatic cytolysis ": 11.330596347800826, "Hepatic function abnormal ": 2.0429653074061216, "Hiccups ": 36.49961914269803, "Human herpesvirus 6 infection ": 56.17913560174131, "Hypersensitivity ": 2.7277282475411715, "Hyponatraemia ": 4.6757248247046, "Inappropriate antidiuretic hormone secretion ": 6.334088484527775, "Intestinal obstruction ": 3.75917015407998, "Liver injury ": 3.6608881760268086, "Mucosal disorder ": 21.41424078711642, "Mucosal inflammation ": 5.61541955424712, "Myocardial ischaemia ": 6.862248400903142, "Necrotising ulcerative gingivostomatitis ": 1640.8684551118154, "Neutropenia ": 3.501889743879388, "Neutrophil count decreased ": 4.169580532282327, "Oxygen saturation decreased ": 3.3625196943629496, "Pancreatitis acute ": 3.350705271393696, "Product administration error ": 2.068666556813258, "Rash maculo-papular ": 3.9648273113514136, "Rash papular ": 13.289759670724608, "Red cell distribution width increased ": 22.663905494117028, "Septic shock ": 4.097623196031904, "Skin hyperpigmentation ": 12.205053323347792, "Skin lesion ": 2.7789558861475787, "Stevens-Johnson syndrome ": 4.661525762191892, "Toxic encephalopathy ": 15.906703000170758, "Toxic epidermal necrolysis ": 32.75162207631664, "White blood cell count decreased ": 2.7750883331793195, "White blood cell count increased ": 3.443732354418665}
\ No newline at end of file
+{"Abdominal pain": 2.0693782950609045, "Alopecia": 5.955642799865957, "Micturition urgency": 80.6509196419714, "Off label use": 2.1609310867627656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/393.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/393.json
index e12c68a4345..325f6de8e60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/393.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/393.json
@@ -1 +1 @@
-{"Blood pressure decreased ": 26.17744205470865, "Heart rate increased ": 25.67937806453716, "Migraine ": 21.79360439143026, "Mycobacterium avium complex infection ": 846.56413802355, "Postural orthostatic tachycardia syndrome ": 622.6024985866085}
\ No newline at end of file
+{"Anti factor VIII antibody positive": 1392.4633636192832, "Factor VIII inhibition": 1020.4188000615862, "Haemarthrosis": 389.0320415415492, "Haemorrhage": 19.04951723366358, "Off label use": 7.116524675191826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/394.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/394.json
index 748142d91b3..85a2af435b0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/394.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/394.json
@@ -1 +1 @@
-{"Drug specific antibody present ": 540.4426166802308, "Haemarthrosis ": 371.1927162278088, "Haemorrhage ": 14.55526280144404, "Head injury ": 40.897408721612, "Muscle haemorrhage ": 222.32659432783367, "Off label use ": 2.354539991363728}
\ No newline at end of file
+{"Ovarian hyperstimulation syndrome": 1163.225652223502}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/395.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/395.json
index 4af228a9cf1..82be39e9416 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/395.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/395.json
@@ -1 +1 @@
-{"Abnormal loss of weight ": 8.097988738803862, "Acidosis ": 7.003727962019444, "Acute kidney injury ": 6.228787249005719, "Adrenal insufficiency ": 10.272192357951718, "Allergic sinusitis ": 182.72392452058568, "Ankylosing spondylitis ": 5.361573722202103, "Antinuclear antibody positive ": 20.817546563769028, "Arrhythmia ": 2.9462299577937614, "Arterial haemorrhage ": 41.14437771362002, "Atrial fibrillation ": 2.9328710162173706, "Balanitis candida ": 218.7026727542693, "Balanoposthitis ": 46.544787654675865, "Blood creatinine increased ": 2.3925308951798296, "Blood glucose abnormal ": 4.100697428310465, "Blood glucose fluctuation ": 3.053651763666667, "Blood iron decreased ": 10.72022974252701, "Blood lactic acid increased ": 9.599695114040616, "Blood potassium increased ": 6.998479867072879, "Blood uric acid increased ": 8.696923788584629, "Bradycardia ": 2.494857303150518, "Candida infection ": 25.41204143331916, "Cardiac failure chronic ": 9.437037854556277, "Cyst ": 11.757929021535752, "Cystitis ": 7.275308835706903, "Dehydration ": 6.025391287107175, "Diabetes mellitus inadequate control ": 3.97884509518968, "Diabetic foot ": 33.98247064535207, "Diabetic ketoacidosis ": 89.44592024531175, "Diabetic ketosis ": 52.805590231642086, "Diabetic neuropathy ": 8.688665250009107, "Dry skin ": 2.0056512877454336, "Dysuria ": 4.041370388861208, "Eosinophilic myocarditis ": 54.64717491053017, "Euglycaemic diabetic ketoacidosis ": 379.8467784748874, "Fournier's gangrene ": 113.05436512855135, "Gastroenteritis ": 3.326236460959717, "Glomerular filtration rate decreased ": 11.458758221066695, "Glycosylated haemoglobin increased ": 7.112116025254086, "Haematocrit increased ": 65.15206964147711, "Haemoglobin increased ": 50.79588195266864, "Hyperglycaemia ": 2.95399909357365, "Hyperkalaemia ": 4.006720734983727, "Hyperlipidaemia ": 3.780612691865135, "Hyperthyroidism ": 6.120619846197168, "Hypoglycaemia ": 4.397203672589612, "Hypophagia ": 3.110412544317012, "Hypotension ": 4.140631330297168, "Hypovolaemia ": 68.58981438559384, "Iron deficiency ": 10.507505644919796, "Joint effusion ": 9.595378390794128, "Ketoacidosis ": 63.66953893745229, "Ketonuria ": 32.904785171522995, "Ketosis ": 35.91606200639334, "Lactic acidosis ": 10.105999062525663, "Left atrial dilatation ": 159.2949034589921, "Medication error ": 3.2566071668004475, "Mental status changes ": 2.4093129759983527, "Metabolic acidosis ": 21.154526142699968, "Mitral valve incompetence ": 4.298817735758627, "Mucosal dryness ": 51.46793241103668, "Necrotising fasciitis ": 26.727844286177287, "Nephrolithiasis ": 2.218609141326887, "Oedema peripheral ": 2.71841044955868, "Osteoarthritis ": 2.3215074124233177, "Pancreatitis acute ": 3.746006424900579, "Pemphigoid ": 4.204358201331185, "Peripheral ischaemia ": 22.54036167742105, "Pollakiuria ": 12.240661494588526, "Polycythaemia ": 25.16137389725629, "Polydipsia ": 9.441444816522113, "Polyuria ": 21.63219746544057, "Presyncope ": 4.06641024417524, "Product monitoring error ": 67.54661012311233, "Product prescribing error ": 3.152934165131456, "Pruritus genital ": 25.75357746727545, "Pulmonary congestion ": 8.528371870009366, "Pyelonephritis ": 8.135602444809566, "Renal disorder ": 5.326138401352498, "Renal impairment ": 2.018041901405577, "Sepsis ": 2.4272270669587845, "Septic shock ": 2.0493199679513547, "Skin disorder ": 5.47350059612092, "Skin ulcer ": 4.484422136846033, "Synovial disorder ": 192.74945276491692, "Synovitis ": 2.824049319653149, "Tendonitis ": 3.5214035165709885, "Thirst ": 13.086715335484769, "Toe amputation ": 26.86507434808359, "Treatment noncompliance ": 2.065064144646137, "Troponin increased ": 18.5630518246315, "Type 2 diabetes mellitus ": 2.287267907190837, "Urinary hesitation ": 21.18056836897433, "Urinary tract infection ": 8.772579285498262, "Urosepsis ": 24.96609213199823, "Ventricular extrasystoles ": 4.039213431661975, "Vitamin B12 decreased ": 42.3645271281246, "Vulvovaginal candidiasis ": 81.26775543369882, "Vulvovaginal discomfort ": 29.0323505464779, "Vulvovaginal pruritus ": 38.23713240228954, "Vulvovaginitis ": 60.44133240945552, "Weight decreased ": 2.4188168141176245, "Weight fluctuation ": 13.872612103885716}
\ No newline at end of file
+{"Anaemia": 2.607560843711775, "Bone marrow failure": 43.85320264691377, "Cachexia": 108.32253882961514, "Drug ineffective": 3.0210516978353774, "Gingival bleeding": 23.57195985885075, "Haemoglobin decreased": 5.888176450739303, "Multiple-drug resistance": 74.46096596188573, "Off label use": 2.024628033525715, "Pancytopenia": 17.193618859104976, "Platelet count decreased": 18.863424071988515, "Product use in unapproved indication": 14.865301818635553, "Refractoriness to platelet transfusion": 3205.272250944176, "Thrombocytopenia": 4.835812534223764, "White blood cell count decreased": 3.0771561735616606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/396.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/396.json
index ab12b30d4fc..af66cfed461 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/396.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/396.json
@@ -1 +1 @@
-{"Malignant neoplasm progression ": 10.47792816281476, "Neutropenia ": 6.181810440331533, "Plasma cell myeloma ": 115.28354830433628}
\ No newline at end of file
+{"Adverse event": 6.811978961626962, "Alanine aminotransferase increased": 2.2303891107413003, "Anaphylactic reaction": 5.030130167685408, "Anaphylactic shock": 2.1454589944833344, "Aspartate aminotransferase increased": 2.316588152999061, "Aspiration": 8.572635537133758, "Blood albumin decreased": 11.072762026873674, "Blood chloride decreased": 33.369018037201094, "Blood magnesium decreased": 14.809533992840915, "Blood sodium decreased": 4.766771884988119, "Blood urea decreased": 52.37347235055133, "Blood urea increased": 2.7560912039608323, "Bone marrow failure": 8.81581645064908, "Bronchopulmonary aspergillosis": 12.45973788943276, "Cholestasis": 4.9458198199253, "Congenital aplasia": 27.61739470440283, "Constipation": 2.148383724398482, "Death": 2.8770921260801754, "Dermatitis bullous": 21.364570214093018, "Dermatitis exfoliative generalised": 6.2066133312875165, "Dermatitis infected": 188.61368844580625, "Drug eruption": 3.061240749645224, "Drug interaction": 2.641515649050951, "Dysphagia": 4.705210760438708, "Encephalopathy": 35.7531092545134, "Erythema": 4.535929816165076, "Febrile bone marrow aplasia": 80.07372076413918, "Flushing": 4.939116509783689, "Graft versus host disease": 10.95782757742808, "Hepatic cytolysis": 11.330596347800826, "Hepatic function abnormal": 2.0429653074061216, "Hiccups": 36.49961914269803, "Human herpesvirus 6 infection": 56.17913560174131, "Hypersensitivity": 2.7277282475411715, "Hyponatraemia": 4.6757248247046, "Inappropriate antidiuretic hormone secretion": 6.334088484527775, "Intestinal obstruction": 3.75917015407998, "Liver injury": 3.6608881760268086, "Mucosal disorder": 21.41424078711642, "Mucosal inflammation": 5.61541955424712, "Myocardial ischaemia": 6.862248400903142, "Necrotising ulcerative gingivostomatitis": 1640.8684551118154, "Neutropenia": 3.50173905433058, "Neutrophil count decreased": 4.169580532282327, "Oxygen saturation decreased": 3.3623397034077804, "Pancreatitis acute": 3.350705271393696, "Product administration error": 2.0685045277070637, "Rash maculo-papular": 3.9648273113514136, "Rash papular": 13.288287129680276, "Red cell distribution width increased": 22.663905494117028, "Septic shock": 4.097623196031904, "Skin hyperpigmentation": 12.205053323347792, "Skin lesion": 2.7789558861475787, "Stevens-Johnson syndrome": 4.661525762191892, "Toxic encephalopathy": 15.906703000170758, "Toxic epidermal necrolysis": 32.75162207631664, "White blood cell count decreased": 2.7750883331793195, "White blood cell count increased": 3.443072677915566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/397.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/397.json
index f15c66f0499..ac1b48d1fe9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/397.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/397.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.942096135529341, "Acute HIV infection ": 193.12131468787092, "Acute kidney injury ": 3.395105202732249, "Adrenal insufficiency ": 3.258032587139684, "Adverse event ": 3.150107791354043, "Alanine aminotransferase increased ": 3.582000136693249, "Ascites ": 2.9907718284534512, "Aspartate aminotransferase increased ": 2.5333785524531174, "Ataxia ": 2.82274568064511, "Atrial septal defect ": 20.260540210180885, "Blood HIV RNA increased ": 77.30947989876877, "Blood alkaline phosphatase increased ": 4.357577160408731, "Blood bilirubin increased ": 2.901572515512855, "Blood creatinine increased ": 2.549051849328, "Blood triglycerides increased ": 5.250018360232792, "Bone disorder ": 4.120061661074426, "CD4 lymphocytes decreased ": 24.19391661546745, "CSF HIV escape syndrome ": 299.2731372212314, "Cerebellar syndrome ": 23.98158578382504, "Cholestasis ": 2.709380811195733, "Congenital anomaly ": 6.176010083784889, "Creatinine renal clearance decreased ": 10.426168998461415, "Developmental delay ": 6.821779447928377, "Dilated cardiomyopathy ": 8.613779352798565, "Drug interaction ": 4.53382146344313, "Drug reaction with eosinophilia and systemic symptoms ": 4.322383048592998, "Drug resistance ": 28.68399807816939, "Encephalitis ": 4.593915265610619, "Enlarged clitoris ": 294.15624518269175, "Exposure during pregnancy ": 5.70048580593172, "Fanconi syndrome ": 23.25402452609354, "Fanconi syndrome acquired ": 22.815972031634843, "Foetal exposure during pregnancy ": 12.020781934089824, "Folliculitis ": 2.116534192884324, "Genotype drug resistance test positive ": 69.99170557169604, "Glomerular filtration rate decreased ": 11.217394176131512, "Glycosuria ": 38.58930676135778, "HIV infection ": 46.538992949554846, "HIV test positive ": 108.94046551656396, "HIV-associated neurocognitive disorder ": 148.60740218812705, "Haemorrhagic diathesis ": 14.743719408191971, "Hepatic function abnormal ": 2.8756629219362466, "Hepatitis B ": 20.994179313240178, "Hepatomegaly ": 4.723320937088181, "Hepatotoxicity ": 7.129990647187765, "Hyperandrogenism ": 593.189358975067, "Hyperbilirubinaemia ": 8.678625914807302, "Hypertriglyceridaemia ": 8.325414961562897, "Hypophosphataemia ": 18.33753547871697, "Immune reconstitution inflammatory syndrome ": 156.74902480651065, "Immune reconstitution inflammatory syndrome associated Kaposi's sarcoma ": 274.1748553756677, "Immune reconstitution inflammatory syndrome associated tuberculosis ": 200.26380668698064, "Kaposi's sarcoma ": 25.14681877757972, "Lactic acidosis ": 4.4671318464322045, "Lipodystrophy acquired ": 17.559610123437768, "Live birth ": 5.471324079702918, "Low birth weight baby ": 8.66007261104367, "Maternal exposure during pregnancy ": 8.152203166310473, "Meningitis cryptococcal ": 57.65008032027289, "Metabolic acidosis ": 5.552220482419975, "Multiple organ dysfunction syndrome ": 2.134475171057049, "Nephropathy toxic ": 50.58966648649003, "Neuropsychological symptoms ": 103.25528014840788, "No adverse event ": 11.87495387159626, "Osteopenia ": 4.308766513322853, "Osteoporosis ": 2.154773322619436, "Pancreatitis acute ": 3.033080190170774, "Pancytopenia ": 2.0240553773343986, "Pathogen resistance ": 43.67132036894899, "Pericardial cyst ": 1588.5393538138464, "Pericardial effusion ": 4.316504174223839, "Peritonitis ": 4.682494025458942, "Pneumocystis jirovecii pneumonia ": 8.01648309077969, "Portal hypertension ": 19.21823019636772, "Premature baby ": 6.460503986240286, "Premature delivery ": 10.735411485505155, "Proteinuria ": 6.503786909132362, "Renal disorder ": 2.907114031179442, "Renal impairment ": 5.387850275683502, "Renal tubular acidosis ": 28.0202350520218, "Renal tubular disorder ": 12.369877000471435, "Renal tubular dysfunction ": 57.13217686600649, "Renal tubular necrosis ": 10.414453272042175, "Treatment failure ": 5.116650058523083, "Treatment noncompliance ": 11.136391395592392, "Tuberculosis ": 10.76878032218702, "Varices oesophageal ": 22.74528012338434, "Ventricular septal defect ": 30.86111790984014, "Viral load increased ": 18.884105716020542, "Viral mutation identified ": 48.289062039213576, "Virologic failure ": 55.0722778670858, "Weight increased ": 2.0329107554446235}
\ No newline at end of file
+{"Blood pressure decreased": 26.17659248993252, "Heart rate increased": 25.67937806453716, "Migraine": 21.79360439143026, "Mycobacterium avium complex infection": 846.56413802355, "Postural orthostatic tachycardia syndrome": 622.6024985866085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/398.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/398.json
index 8bfd2f929d1..e842d3c5940 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/398.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/398.json
@@ -1 +1 @@
-{"Diarrhoea ": 2.3874353152932573, "Product substitution issue ": 79.69252866459298}
\ No newline at end of file
+{"Drug specific antibody present": 540.4426166802308, "Haemarthrosis": 371.1927162278088, "Haemorrhage": 14.55526280144404, "Head injury": 40.897408721612, "Muscle haemorrhage": 222.32659432783367, "Off label use": 2.354447260002122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/399.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/399.json
index 4645a1afd45..2e6ac6ab940 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/399.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/399.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.7034248483745524, "Acute kidney injury ": 5.4124060858477, "Aplasia pure red cell ": 18.74988426690793, "Autonomic neuropathy ": 194.14946612919385, "Blood bilirubin increased ": 12.182984772246114, "Blood creatine phosphokinase increased ": 3.789295374980386, "Blood creatinine increased ": 6.0784234169184375, "Blood phosphorus decreased ": 73.82414740774543, "Caesarean section ": 26.86289957186088, "Drug resistance ": 19.236133938849942, "Dysarthria ": 3.73013279505712, "Fanconi syndrome acquired ": 41.46213260682574, "Foetal exposure during pregnancy ": 3.993836754884389, "Genotype drug resistance test positive ": 232.04572794552456, "Hepatic cytolysis ": 4.842451934203848, "Hepatic enzyme increased ": 3.491546694019553, "Hypercholesterolaemia ": 24.183076725052317, "Hyperkalaemia ": 3.2492427253827123, "Hypertriglyceridaemia ": 19.27069761347895, "Ileus ": 27.70636651902821, "Immune reconstitution inflammatory syndrome ": 297.824846055731, "Lactic acidosis ": 4.626745267934338, "Liver function test abnormal ": 5.552062979442419, "Maternal exposure during pregnancy ": 4.4599457388284085, "Nephrolithiasis ": 5.844605947168194, "Neuropathy peripheral ": 3.7250897783491146, "Neurotoxicity ": 24.573582278336744, "Osteonecrosis ": 2.189586290976137, "Photosensitivity reaction ": 15.25648437215026, "Portal hypertension ": 54.101806259511264, "Potentiating drug interaction ": 73.46934545318256, "Rash maculo-papular ": 4.957008854912117, "Renal failure ": 3.451983575293134, "Virologic failure ": 45.5129816677031}
\ No newline at end of file
+{"Abnormal loss of weight": 8.097988738803862, "Acidosis": 7.003727962019444, "Acute kidney injury": 6.228787249005719, "Adrenal insufficiency": 10.272192357951718, "Allergic sinusitis": 182.72392452058568, "Ankylosing spondylitis": 5.361573722202103, "Antinuclear antibody positive": 20.817546563769028, "Arrhythmia": 2.9462299577937614, "Arterial haemorrhage": 41.14437771362002, "Atrial fibrillation": 2.9327908958384183, "Balanitis candida": 218.7026727542693, "Balanoposthitis": 46.544787654675865, "Blood creatinine increased": 2.3925308951798296, "Blood glucose abnormal": 4.100697428310465, "Blood glucose fluctuation": 3.053651763666667, "Blood iron decreased": 10.72022974252701, "Blood lactic acid increased": 9.599695114040616, "Blood potassium increased": 6.998479867072879, "Blood uric acid increased": 8.696923788584629, "Bradycardia": 2.4947790674104136, "Candida infection": 25.41204143331916, "Cardiac failure chronic": 9.437037854556277, "Cyst": 11.757929021535752, "Cystitis": 7.275308835706903, "Dehydration": 6.025069052070881, "Diabetes mellitus inadequate control": 3.97884509518968, "Diabetic foot": 33.98247064535207, "Diabetic ketoacidosis": 89.44592024531175, "Diabetic ketosis": 52.805590231642086, "Diabetic neuropathy": 8.688665250009107, "Dry skin": 2.0056512877454336, "Dysuria": 4.041370388861208, "Eosinophilic myocarditis": 54.64717491053017, "Euglycaemic diabetic ketoacidosis": 379.8467784748874, "Fournier's gangrene": 113.05436512855135, "Gastroenteritis": 3.326236460959717, "Glomerular filtration rate decreased": 11.458758221066695, "Glycosylated haemoglobin increased": 7.112116025254086, "Haematocrit increased": 65.15206964147711, "Haemoglobin increased": 50.79588195266864, "Hyperglycaemia": 2.95399909357365, "Hyperkalaemia": 4.006167707755752, "Hyperlipidaemia": 3.780612691865135, "Hyperthyroidism": 6.120062034157296, "Hypoglycaemia": 4.397055038434049, "Hypophagia": 3.110412544317012, "Hypotension": 4.1405354798738125, "Hypovolaemia": 68.58981438559384, "Iron deficiency": 10.507505644919796, "Joint effusion": 9.595378390794128, "Ketoacidosis": 63.66953893745229, "Ketonuria": 32.904785171522995, "Ketosis": 35.91606200639334, "Lactic acidosis": 10.105999062525663, "Left atrial dilatation": 159.2949034589921, "Medication error": 3.256373327754482, "Mental status changes": 2.4093129759983527, "Metabolic acidosis": 21.154526142699968, "Mitral valve incompetence": 4.298817735758627, "Mucosal dryness": 51.46793241103668, "Necrotising fasciitis": 26.727844286177287, "Nephrolithiasis": 2.218242271339193, "Oedema peripheral": 2.7183432185467837, "Osteoarthritis": 2.3215074124233177, "Pancreatitis acute": 3.746006424900579, "Pemphigoid": 4.204358201331185, "Peripheral ischaemia": 22.54036167742105, "Pollakiuria": 12.240661494588526, "Polycythaemia": 25.16137389725629, "Polydipsia": 9.441444816522113, "Polyuria": 21.63219746544057, "Presyncope": 4.06641024417524, "Product monitoring error": 67.54661012311233, "Product prescribing error": 3.152934165131456, "Pruritus genital": 25.75357746727545, "Pulmonary congestion": 8.528371870009366, "Pyelonephritis": 8.135602444809566, "Renal disorder": 5.3253515424097, "Renal impairment": 2.018041901405577, "Sepsis": 2.4272270669587845, "Septic shock": 2.0493199679513547, "Skin disorder": 5.47350059612092, "Skin ulcer": 4.484422136846033, "Synovial disorder": 192.74945276491692, "Synovitis": 2.824049319653149, "Tendonitis": 3.5214035165709885, "Thirst": 13.086715335484769, "Toe amputation": 26.86507434808359, "Treatment noncompliance": 2.065064144646137, "Troponin increased": 18.5630518246315, "Type 2 diabetes mellitus": 2.287267907190837, "Urinary hesitation": 21.18056836897433, "Urinary tract infection": 8.772579285498262, "Urosepsis": 24.96609213199823, "Ventricular extrasystoles": 4.039213431661975, "Vitamin B12 decreased": 42.3645271281246, "Vulvovaginal candidiasis": 81.26775543369882, "Vulvovaginal discomfort": 29.0323505464779, "Vulvovaginal pruritus": 38.23713240228954, "Vulvovaginitis": 60.44133240945552, "Weight decreased": 2.4188168141176245, "Weight fluctuation": 13.872612103885716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/4.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/4.json
index f4954cc89ab..a27a2674774 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/4.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/4.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 6.662661300633792, "Abdominal pain upper ": 3.767436368640949, "Adjustment disorder with depressed mood ": 61.32956318748553, "Adverse drug reaction ": 2.3489341104905144, "Alanine aminotransferase abnormal ": 14.165756972667689, "Alopecia ": 6.1739925216996125, "Amnesia ": 5.919864396869161, "Anal abscess ": 3.5072282205427, "Anti-cyclic citrullinated peptide antibody ": 64.26207967972435, "Anti-cyclic citrullinated peptide antibody positive ": 28.10478528654915, "Antibody test positive ": 6.024795455616933, "Arthritis ": 5.744678399975245, "Arthropathy ": 14.998149458397153, "Asthma ": 2.47057454260862, "Autoimmune disorder ": 23.456468274596308, "Back injury ": 25.370515987528453, "Basal cell carcinoma ": 5.950654589065102, "Blepharospasm ": 22.653366617450757, "Blister ": 13.394261660132887, "Blood cholesterol ": 12.165598739048407, "Blood cholesterol increased ": 15.955775943618322, "Blood magnesium increased ": 15.28101222462559, "Blood parathyroid hormone decreased ": 21.417666916848027, "Body height below normal ": 23.44327185612402, "Body temperature ": 2.2542450274397665, "Bone density increased ": 20.21140819726369, "Bone erosion ": 57.41947948371461, "Breast cancer stage I ": 22.914189167139487, "Breast cancer stage II ": 39.72721745231772, "Breast cancer stage III ": 88.56662650220915, "Bunion operation ": 16.794693512512385, "Bursitis ": 30.32749427483968, "C-reactive protein ": 17.56995773061908, "C-reactive protein abnormal ": 29.590680782105757, "C-reactive protein increased ": 10.926748426316138, "Colitis ulcerative ": 3.728922828078847, "Condition aggravated ": 2.791753330346998, "Confusional state ": 4.399914261458783, "Contraindicated product administered ": 17.164194004458192, "Contusion ": 5.2053575294082295, "Crohn's disease ": 2.701329679556612, "Cyst ": 2.965356649095945, "Deafness neurosensory ": 3.366378395477557, "Deep vein thrombosis postoperative ": 35.64437564301909, "Deformity ": 8.234308422778563, "Delirium ": 3.728052715681324, "Depression ": 2.2616518827066425, "Disability ": 11.797666383255653, "Discomfort ": 5.391043992362601, "Dislocation of vertebra ": 56.30628458589917, "Drug hypersensitivity ": 6.375439571464654, "Drug ineffective ": 2.138160620783381, "Drug intolerance ": 7.470687869213298, "Drug specific antibody ": 3.0548685235044983, "Drug tolerance ": 5.714828708205755, "Drug tolerance decreased ": 10.428915828017496, "Drug-induced liver injury ": 2.112925007653574, "Dry mouth ": 4.109238286875727, "Duodenal ulcer perforation ": 28.070132257286875, "Ear infection ": 4.468821374598521, "Ear pain ": 5.723888975939825, "Enthesopathy ": 18.75733777735539, "Epigastric discomfort ": 4.412475309196731, "Epilepsy ": 4.1249858735047225, "Epstein-Barr viraemia ": 4.78309512281517, "Exostosis ": 20.170083708797023, "Facet joint syndrome ": 51.00714681532218, "Fear of injection ": 12.054149175888003, "Fibromyalgia ": 13.873957033250612, "Finger deformity ": 4.600584458865994, "Folliculitis ": 37.460205707026105, "Foot deformity ": 11.857098787093443, "Foot operation ": 6.443164225527807, "Gait inability ": 5.8667863394743, "Gastrointestinal disorder ": 6.275994403508665, "Gastrointestinal toxicity ": 2.9885736471643223, "Gastrooesophageal reflux disease ": 4.377232313250558, "General physical health deterioration ": 4.2219580720072685, "Glossodynia ": 12.550991274823414, "Granuloma ": 2.030698364835504, "Granuloma skin ": 15.88039528634048, "Grip strength decreased ": 7.826887145723598, "Hand deformity ": 15.581628363004784, "Helicobacter infection ": 18.727975104458583, "Hepatic enzyme increased ": 5.273447907018985, "Hip arthroplasty ": 9.4061206372515, "Human antichimeric antibody positive ": 31.064447951053896, "Hypercalcaemia ": 3.2440785709175644, "Hypercholesterolaemia ": 21.11295101876185, "Hypersensitivity ": 3.341995080375345, "Ill-defined disorder ": 11.724179488087708, "Impaired healing ": 26.35880766796328, "Infection ": 5.802664379808832, "Inflammation ": 6.304272084763363, "Inflammatory marker increased ": 3.102967102413823, "Infusion related reaction ": 8.092317732085135, "Infusion site reaction ": 142.6571936681913, "Injury ": 5.999450956616284, "Intentional product use issue ": 6.020497934137922, "Irritable bowel syndrome ": 28.4834974701842, "Joint destruction ": 23.21624083253435, "Joint dislocation ": 5.583260710639072, "Joint effusion ": 4.447180908591867, "Joint injury ": 2.647338466343225, "Joint range of motion decreased ": 16.99471452308404, "Joint stiffness ": 3.577990529636573, "Joint swelling ": 10.146508111296583, "Juvenile idiopathic arthritis ": 12.696302798484156, "Keratitis ": 3.641507070727722, "Knee arthroplasty ": 9.61221184378673, "Lip dry ": 35.09686344749346, "Live birth ": 20.489959678244837, "Liver function test increased ": 7.513354477643465, "Liver injury ": 6.237150576884588, "Lower respiratory tract infection ": 17.774333238911268, "Lung disorder ": 3.866684554856171, "Lupus vulgaris ": 7.41983028310854, "Lupus-like syndrome ": 2.531384307836116, "Maternal exposure during pregnancy ": 4.02870271799851, "Mean cell haemoglobin decreased ": 12.679799079149811, "Mean cell volume decreased ": 15.183263770956415, "Mean platelet volume decreased ": 33.45090619095597, "Medication error ": 2.57033741951046, "Mobility decreased ": 4.913332455544526, "Monocyte count increased ": 6.667587432343806, "Muscle injury ": 55.36681997060485, "Muscle spasticity ": 14.691566236391054, "Musculoskeletal deformity ": 94.34284544781342, "Musculoskeletal pain ": 8.044003778959254, "Musculoskeletal stiffness ": 2.4516636390671667, "Nail disorder ": 32.04519269060555, "Nasopharyngitis ": 5.978449769229223, "Night sweats ": 7.689297613991, "Obesity ": 11.236654246463274, "Onychomadesis ": 29.414550483968867, "Osteoarthritis ": 6.140323854067137, "Panniculitis ": 7.340176358882203, "Pemphigus ": 10.652675469681675, "Pericarditis ": 3.0618943151788667, "Peripheral swelling ": 4.307888223523494, "Peripheral venous disease ": 6.9820024103254, "Physical disability ": 2.921572667942407, "Pleural fibrosis ": 22.850581039941893, "Pleural thickening ": 11.486349846877108, "Presbyacusis ": 33.73003723200497, "Prescribed underdose ": 2.223185444810729, "Product use issue ": 2.535007626375071, "Psoriatic arthropathy ": 3.3826314681527347, "Pulmonary fibrosis ": 2.4159939921091484, "Red blood cell sedimentation rate ": 30.053492596664142, "Red blood cell sedimentation rate abnormal ": 11.234574149417629, "Red blood cell sedimentation rate increased ": 5.46967153602994, "Red cell distribution width decreased ": 69.3982950456062, "Red cell distribution width increased ": 2.5076774300706712, "Respiratory disorder ": 5.856262404865904, "Respiratory tract congestion ": 2.875009572772489, "Retinitis ": 7.384913383470053, "Rheumatic fever ": 13.66114112684857, "Rheumatoid arthritis ": 6.104104497081946, "Rheumatoid factor positive ": 13.04151135261995, "Rheumatoid lung ": 15.62240243767165, "Rheumatoid nodule ": 12.432784570423705, "Sciatica ": 2.982553719062857, "Seronegative arthritis ": 7.116980147053906, "Sinusitis ": 12.640464995476274, "Sleep disorder due to general medical condition, insomnia type ": 55.90672885845112, "Spinal fusion surgery ": 4.4837285779646905, "Spondylitis ": 3.818274494303122, "Stomatitis ": 6.810092634839062, "Swelling ": 4.964920347885803, "Swollen joint count increased ": 19.69115961061168, "Synovitis ": 10.257744862955487, "Systemic lupus erythematosus ": 6.677206798693604, "Systemic lupus erythematosus rash ": 8.6466802816011, "Tenosynovitis ": 2.9935436534030835, "Therapeutic product effect decreased ": 13.289828842623251, "Treatment failure ": 4.0626569741839, "Type 2 diabetes mellitus ": 2.1298724282569634, "Vascular access complication ": 18.852504922564123, "Viral upper respiratory tract infection ": 3.745452782178869, "Walking aid user ": 6.152885800556383, "Weight increased ": 3.222054334476333, "White blood cell count abnormal ": 5.242781843671874, "Wound ": 6.754910648109536, "Wound infection ": 8.122044523976754, "Wrist deformity ": 15.495063966225494, "X-ray abnormal ": 10.694081544966172}
\ No newline at end of file
+{"Accidental underdose": 181.5460973674148, "Blood glucose abnormal": 67.53836703459412, "Blood glucose decreased": 19.4507735038502, "Blood glucose fluctuation": 29.97973339863641, "Blood glucose increased": 36.43872731950109, "Device malfunction": 2.7363928615479134, "Diabetes mellitus inadequate control": 13.576814997310883, "Drug hypersensitivity": 2.5685925801274303, "Drug ineffective": 2.3805343244119905, "Feeling abnormal": 2.0871794255666787, "Flatulence": 2.3710292484164674, "Glycosylated haemoglobin increased": 46.47747577782364, "Hyperglycaemia": 16.96847515543729, "Hyperinsulinaemic hypoglycaemia": 65.58767067997874, "Hypoglycaemia": 27.470713776110543, "Hypoglycaemic coma": 9.719689281518743, "Incorrect dose administered": 26.08744557641807, "Incorrect product administration duration": 7.1564066121743215, "Increased appetite": 4.18889015468786, "Injection site bruising": 11.780928036942004, "Injection site erythema": 2.1638517789902854, "Injection site haematoma": 2.4163040735604557, "Injection site haemorrhage": 19.351303492751885, "Injection site mass": 10.178046675029629, "Injection site pain": 5.027771642529202, "Injection site pruritus": 4.789358893265909, "Injection site rash": 7.09270767931323, "Injection site reaction": 2.407472071824382, "Injection site urticaria": 8.595450092692062, "Injury associated with device": 22.5503474954124, "Ketoacidosis": 6.167752790524029, "Lipodystrophy acquired": 8.842062201004781, "Nocturia": 5.710478804883988, "Pancreatic carcinoma": 2.1075353199285973, "Product administration error": 2.4766469037637515, "Product dose omission issue": 6.9774223695475, "Product storage error": 17.368902802593887, "Product substitution issue": 7.750088083341915, "Pruritus": 2.9348985678726804, "Rash pruritic": 2.645049380968972, "Skin reaction": 2.0084283033524843, "Therapeutic response unexpected": 27.087702835363736, "Visual impairment": 3.506080805167576, "Weight decreased": 2.27398926473085, "Weight increased": 4.88030913240921, "Wound": 2.4507760237035305, "Wrong product administered": 12.477415229121013, "Wrong technique in product usage process": 2.684229180269249}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/40.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/40.json
index fb3450b4f64..1c025825b65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/40.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/40.json
@@ -1 +1 @@
-{"Abdominal distension ": 3.292372458892356, "Abdominal pain upper ": 2.793266605371511, "Accidental exposure to product ": 16.437353676171643, "Adverse reaction ": 3.8754338835926543, "Alopecia ": 5.462579180612203, "Anti-cyclic citrullinated peptide antibody positive ": 2.0815128760090427, "Antinuclear antibody positive ": 3.1776023626917387, "Anuria ": 14.203559456009351, "Aphasia ": 2.924425608295886, "Arteriospasm coronary ": 5.793762369576544, "Aura ": 23.18856569337211, "Autoimmune thyroiditis ": 2.4242388451671504, "Back injury ": 7.091021193884172, "Blepharospasm ": 42.20960970134791, "Blood pressure measurement ": 9.192329819907563, "Bowel movement irregularity ": 3.243493863060225, "Brain fog ": 3.2686543840351256, "Brain injury ": 2.140162884801881, "Breast cancer stage III ": 7.79228822361316, "Bursitis ": 3.1401533866807663, "C-reactive protein abnormal ": 3.5459097328053164, "Cerebellar infarction ": 3.17833712947992, "Cerebrospinal fluid leakage ": 4.103051420283254, "Cervicogenic headache ": 71.70637535375774, "Cluster headache ": 4.140378339110549, "Coeliac disease ": 4.915619082930372, "Colitis ischaemic ": 3.1065727595164567, "Colour blindness ": 9.897907229596813, "Communication disorder ": 9.292344786464842, "Concussion ": 22.57161702308696, "Constipation ": 15.590454420594584, "Contraindicated product administered ": 2.795384371498977, "Coronavirus infection ": 3.7059863908644046, "Craniocerebral injury ": 5.950020998808764, "Depression suicidal ": 2.5191300588259784, "Device defective ": 8.770505469473079, "Device delivery system issue ": 4.530822690466712, "Device difficult to use ": 207.13185037430225, "Device issue ": 15.21966480342774, "Device leakage ": 5.256466733102113, "Device malfunction ": 4.727205347343143, "Device use error ": 11.108017685912287, "Device use issue ": 2.616855563620365, "Discomfort ": 2.3319618163685942, "Disturbance in attention ": 2.743612918391288, "Drug dose omission by device ": 77.35683228485748, "Drug effect less than expected ": 3.669005170764745, "Drug ineffective ": 2.314777476444408, "Drug ineffective for unapproved indication ": 11.236269723556031, "Drug intolerance ": 7.435817250022382, "Dyschezia ": 7.027550279297166, "Dyspepsia ": 4.382903780844188, "Epilepsy ": 6.548548839867366, "Extrapyramidal disorder ": 9.769733496966031, "Faecaloma ": 6.849467924341745, "Faeces hard ": 9.385272073359168, "Fear of injection ": 6.181806712829599, "Fixed eruption ": 3.780103456668012, "Flatulence ": 2.209211075706495, "Flushing ": 2.240911460250971, "Galactorrhoea ": 3.7777804707738607, "Gastrointestinal infection ": 2.0943316134140035, "Gastrointestinal motility disorder ": 7.850400456265434, "Gastrointestinal obstruction ": 5.593811570637025, "Gastrointestinal sounds abnormal ": 2.1280137911869565, "Gastrooesophageal reflux disease ": 7.421474488177809, "Gingival disorder ": 2.522263517015274, "Heart rate abnormal ": 2.8712571655277626, "Hostility ": 32.03911444907603, "Hyperaesthesia teeth ": 5.924811631390887, "Hypoaesthesia ": 2.8584624201666777, "Ileus ": 2.2143310170188677, "Ileus paralytic ": 2.6753985625393493, "Impaired gastric emptying ": 6.574601778911032, "Incorrect disposal of product ": 129.5628809387308, "Incorrect dose administered ": 2.809875304302876, "Incorrect dose administered by device ": 11.13212766531186, "Incorrect route of product administration ": 6.444768777197345, "Initial insomnia ": 2.2405672739137503, "Injection site bruising ": 4.126477337170444, "Injection site extravasation ": 9.79943382609506, "Injection site haemorrhage ": 10.126202711468084, "Injection site hypersensitivity ": 4.933994065692652, "Injection site indentation ": 39.54495787148606, "Injection site irritation ": 7.575003261939572, "Injection site pruritus ": 2.231691375073261, "Injection site rash ": 6.683290972784993, "Injection site urticaria ": 9.125992622190436, "Injection site vesicles ": 3.04523206805003, "Injury associated with device ": 2.901570474306605, "Intercepted product administration error ": 24.72587207117854, "Intestinal obstruction ": 4.314971690625816, "Irritable bowel syndrome ": 2.018269559401185, "Jaw disorder ": 4.727877554123955, "Libido increased ": 30.87106876122801, "Loose tooth ": 3.594372556266701, "Lymphatic malformation ": 46.122476759013765, "Macular dystrophy congenital ": 531.1042025712393, "Mastoiditis ": 153.45786364683454, "May-Thurner syndrome ": 91.6856170724836, "Medication overuse headache ": 57.030724371770056, "Memory impairment ": 6.244432116238149, "Menopausal symptoms ": 3.506349710630265, "Menopause ": 3.4660200546216697, "Middle insomnia ": 7.415357607661773, "Migraine ": 28.98863992328096, "Migraine with aura ": 10.56067372608402, "Migraine without aura ": 15.321054923766384, "Muscle spasms ": 2.9961601927085346, "Muscle tightness ": 2.227416524332326, "Muscle twitching ": 3.850955047190574, "Neck pain ": 2.473767578477926, "Needle issue ": 8.790527182282677, "Neovascularisation ": 448.1284763804093, "Nephrolithiasis ": 2.401879705200065, "Neurofibrosarcoma ": 55.87139936988857, "Night blindness ": 12.001838663294162, "Nightmare ": 3.228535423380225, "Normal newborn ": 4.303093242707801, "Onychoclasis ": 2.475155971563972, "Otitis media ": 23.196685106510127, "Ovarian cyst ": 3.138392394705308, "Panic attack ": 2.133936587057049, "Panic disorder ": 2.3617556178445547, "Paradoxical drug reaction ": 52.13227418084397, "Paraesthesia ": 2.331078459727568, "Paranasal cyst ": 568.2280886626462, "Personality disorder ": 21.65268290935972, "Photophobia ": 2.33155031839947, "Polyp ": 2.186691439366262, "Poor dental condition ": 17.99253239661731, "Poor quality sleep ": 6.2234132316662025, "Post-traumatic neck syndrome ": 128.7630895554759, "Post-traumatic stress disorder ": 2.721819665250952, "Product administered at inappropriate site ": 2.807321070644702, "Product administration interrupted ": 7.403961965885593, "Product communication issue ": 23.80309226130351, "Product storage error ": 6.538863636427508, "Product supply issue ": 2.331346588133291, "Product use in unapproved indication ": 3.0424462463688844, "Quality of life decreased ": 2.3884039981149265, "Raynaud's phenomenon ": 10.593773639948637, "Rebound effect ": 3.0889517882026007, "Red cell distribution width increased ": 2.4283902425707447, "Reversible cerebral vasoconstriction syndrome ": 5.032540246222401, "Rib fracture ": 4.934335273085088, "Rubber sensitivity ": 57.283429019661945, "Sedation ": 3.2701500683888534, "Skin cancer ": 2.3605921477931244, "Skin swelling ": 2.013434367424705, "Sleep disorder ": 2.193179179637418, "Small intestinal obstruction ": 2.363202196734796, "Snoring ": 2.2724801373612182, "Soft tissue injury ": 115.21539016610366, "Status migrainosus ": 61.67360571409265, "Sternal fracture ": 82.93110268535288, "Stress ": 7.349167480154613, "Syringe issue ": 7.012782889014786, "Taste disorder ": 8.82955943938664, "Tension headache ": 5.216569843638351, "Therapeutic product effect decreased ": 4.364717978775044, "Therapeutic product effect delayed ": 2.6244849548115163, "Therapeutic product effect incomplete ": 2.9726681898622136, "Therapeutic response decreased ": 3.885866496724712, "Therapeutic response shortened ": 20.63305862345607, "Therapy partial responder ": 9.812814041886568, "Tinnitus ": 2.242797215287148, "Treatment failure ": 2.3678015546102187, "Trigeminal neuralgia ": 2.8302517731531687, "Vascular malformation ": 255.05513456673583, "Vestibular disorder ": 6.498008729751371, "Vestibular migraine ": 14.547280768195286, "Visual field defect ": 3.68479689295694, "Volvulus ": 7.2024479200543645, "Weight increased ": 3.2878357991115723, "Wrong technique in device usage process ": 3.506081451669452, "Wrong technique in product usage process ": 7.93347978391759}
\ No newline at end of file
+{"Abdominal discomfort": 2.7221421031876054, "Anhedonia": 8.890327335125598, "Anxiety": 3.07090957720799, "Condition aggravated": 3.023400683919979, "Depression": 7.246560925543954, "Drug ineffective": 3.684019742427876, "Drug interaction": 4.938149239229934, "Drug intolerance": 4.066895885148028, "Dry mouth": 5.464969975574975, "Electrocardiogram QT prolonged": 7.206060387942967, "Extrapyramidal disorder": 34.82692629723762, "Hepatic enzyme increased": 4.059472798678062, "Hyperhidrosis": 3.735703102688356, "Hyponatraemia": 11.996810438920177, "Off label use": 2.166816048092389, "Overdose": 2.7657241129280954, "Product use in unapproved indication": 3.321607137994649, "Sedation complication": 50.73090015381563, "Sleep disorder": 5.576274140013453, "Suicidal ideation": 9.64852572009864, "Suicide attempt": 4.243832930264444, "Tachycardia": 5.76843848818348, "Therapy non-responder": 17.173636220924504, "Type 2 diabetes mellitus": 20.76083486774135, "Vertigo": 4.40874978521634, "Weight decreased": 2.26619573459899, "Weight increased": 4.625625762765139}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/400.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/400.json
index 1a8bc712e3a..28444596236 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/400.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/400.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.581765815120143, "Adverse event ": 8.35749858790516, "Angioedema ": 7.385229777316709, "Asthenia ": 7.7767120719421134, "Atrial enlargement ": 775.9646085531555, "Blood pressure decreased ": 4.593591274828652, "Cardiac failure ": 6.397124660390862, "Dehydration ": 6.559043068384429, "Disease progression ": 3.262781432038645, "Gait disturbance ": 4.454981946324356, "Hyperkalaemia ": 6.505488191029216, "Hypotension ": 4.9821225238333176, "Hypovolaemia ": 71.48626663745546, "N-terminal prohormone brain natriuretic peptide increased ": 148.79490798639085, "Overdose ": 2.644313198169167, "Pulmonary arterial pressure increased ": 244.09730022711895, "Tricuspid valve incompetence ": 58.410053902137946, "Urinary tract infection ": 5.65841191026963}
\ No newline at end of file
+{"Malignant neoplasm progression": 10.47792816281476, "Neutropenia": 6.181544644224155, "Plasma cell myeloma": 115.28354830433628}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/401.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/401.json
index 9ec8a41db7a..8b15e308f42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/401.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/401.json
@@ -1 +1 @@
-{"Abscess ": 2.148186430149844, "Adverse drug reaction ": 5.681285175493105, "Alanine aminotransferase increased ": 3.316099199981201, "Allergic oedema ": 6.802785023101931, "Alopecia ": 2.65383380768433, "Amyotrophic lateral sclerosis ": 3.6315243472946697, "Ankylosing spondylitis ": 7.850933516294374, "Anticipatory anxiety ": 250.2132357798923, "Antinuclear antibody positive ": 2.532852673095394, "Apparent death ": 6.305589108307958, "Appendix disorder ": 8.868550832362711, "Arteriospasm coronary ": 2.431936267398563, "Arthritis ": 3.985767813405747, "Arthritis bacterial ": 3.0387715170336347, "Arthritis infective ": 3.891164551228452, "Arthrodesis ": 14.831745069338524, "Arthropathy ": 7.210858829302754, "Arthropod bite ": 3.0598672708087853, "Aspartate aminotransferase increased ": 3.598534707494162, "Basal cell carcinoma ": 19.814006380777894, "Bipolar disorder ": 5.963753788941821, "Blood creatinine decreased ": 3.705325774906325, "Blood magnesium increased ": 8.471494290177265, "Blood parathyroid hormone decreased ": 74.07229167258488, "Bone cyst ": 9.510019296380248, "Bone erosion ": 12.31566512792174, "Bone hypertrophy ": 28.954620418650947, "Breast abscess ": 9.447609357133034, "Bronchitis chronic ": 14.59417765144482, "Bursitis ": 2.164206841024705, "Butterfly rash ": 5.1917373130449205, "C-reactive protein abnormal ": 21.535569730360656, "C-reactive protein decreased ": 33.268955885801326, "C-reactive protein increased ": 5.6046289040971216, "Carpal tunnel syndrome ": 7.316151262467264, "Cartilage injury ": 5.083033701045409, "Coeliac disease ": 3.1492798545245924, "Condition aggravated ": 3.388936142415284, "Contraindicated product administered ": 13.452831282530967, "Contrast media allergy ": 46.46160808954346, "Crohn's disease ": 2.5538235771452324, "Cyst ": 2.812616257494577, "Dactylitis ": 26.875964891006127, "Deafness neurosensory ": 2.1154314104426546, "Deformity ": 3.6368264206230574, "Demyelination ": 2.676618414305116, "Dental caries ": 2.9782234198593858, "Dermatitis allergic ": 4.674872070874673, "Disability ": 2.649641844161177, "Diverticulitis ": 3.057086490494179, "Drug eruption ": 5.334107404167554, "Drug hypersensitivity ": 10.07482545455558, "Drug ineffective ": 5.9737105508558175, "Drug intolerance ": 12.402724176089857, "Drug tolerance ": 3.602282378117938, "Drug tolerance decreased ": 16.58228362061501, "Drug use disorder ": 28.38479183045444, "Dry eye ": 3.4568066204841483, "Elbow deformity ": 55.28532005285244, "Enthesopathy ": 10.666175334870616, "Epicondylitis ": 3.700376135537051, "Epigastric discomfort ": 2.0186486671499395, "Episcleritis ": 11.998422687703528, "Exostosis ": 2.9834508503562867, "Eye disorder ": 2.873255550392474, "Eye operation ": 5.346340697528044, "Fat necrosis ": 22.02210697040369, "Fear of injection ": 11.73309678014015, "Femur fracture ": 5.1506064497910975, "Fibromyalgia ": 5.443243808640176, "Fine motor skill dysfunction ": 4.373285539671607, "Finger deformity ": 14.096454907523595, "Foetal death ": 2.76127324470853, "Food allergy ": 6.081150035495683, "Foot deformity ": 8.985730703069285, "Frustration tolerance decreased ": 4.007564142364574, "Gait inability ": 3.1174733891132624, "Gastrointestinal disorder ": 2.0760346095851965, "Gastrointestinal inflammation ": 3.056925040868808, "Gastrointestinal toxicity ": 17.718969571538267, "Goitre ": 2.9666740776207483, "Granuloma skin ": 73.18989470067538, "Grip strength decreased ": 3.462629443539892, "HLA marker study positive ": 123.61483817330104, "Hepatic enzyme abnormal ": 3.4964052039680613, "Hepatic enzyme increased ": 3.25898124994273, "Hepatic fibrosis ": 10.122942352231377, "Hepatotoxicity ": 4.832846870144331, "Herpes ophthalmic ": 3.065783985862817, "Hip arthroplasty ": 2.256174423315356, "Hip surgery ": 2.418730405285088, "Hypercalcaemia ": 14.266525093350074, "Hypercholesterolaemia ": 3.911389547997099, "Hypersensitivity ": 2.086711100693696, "Hypersensitivity vasculitis ": 13.945891487517772, "Immobile ": 4.829618637233338, "Immune system disorder ": 3.026578798794174, "Immunodeficiency ": 8.689095809016184, "Immunosuppression ": 2.3579055559047446, "Impaired healing ": 2.7830309969157194, "Impaired work ability ": 3.861505527848524, "Increased tendency to bruise ": 2.703611448780231, "Infection ": 3.261610439706248, "Inflammation ": 7.753574742263338, "Infusion related reaction ": 5.363018848885099, "Infusion site reaction ": 4.003917278550165, "Injection site bruising ": 7.9123858164873395, "Injection site discolouration ": 3.8228625315288856, "Injection site hypersensitivity ": 2.6018255195136555, "Injection site rash ": 3.408703104418113, "Injection site reaction ": 2.529148801741128, "Injection site urticaria ": 3.2057358762172123, "Injection site vesicles ": 2.6492935831254703, "Intervertebral disc disorder ": 12.63241443450103, "Intervertebral disc protrusion ": 3.064529740748831, "Intestinal sepsis ": 26.343019894896837, "Intra-abdominal fluid collection ": 4.916635187926729, "Iritis ": 2.1017291151665374, "Joint arthroplasty ": 4.526261366401162, "Joint destruction ": 10.2415698516852, "Joint effusion ": 3.564680666890032, "Joint injury ": 19.67202122347509, "Joint laxity ": 30.58901823370553, "Joint lock ": 3.242084077554121, "Joint noise ": 3.36417806254582, "Joint range of motion decreased ": 7.721827725946437, "Joint stiffness ": 7.448883067901711, "Joint swelling ": 11.469738339878925, "Joint warmth ": 6.124928793805195, "Juvenile idiopathic arthritis ": 4.09626974103659, "Knee arthroplasty ": 9.178121599585564, "Knee deformity ": 6.484079502840394, "Kyphoscoliosis ": 84.67629880236318, "Laboratory test abnormal ": 2.0135594067108755, "Latent tuberculosis ": 17.5118111608106, "Limb deformity ": 4.49399211616613, "Lipoma ": 2.512218287165735, "Liver disorder ": 4.627624697476847, "Liver function test increased ": 2.021581926342047, "Localised infection ": 3.8850356594788753, "Loss of personal independence in daily activities ": 4.707693381479931, "Lower respiratory tract infection ": 3.8164781746322, "Lupus-like syndrome ": 3.593545189691137, "Lymphoma ": 3.4998076706520127, "Malignant melanoma ": 2.276871814387254, "Mass excision ": 21.894055788917104, "Mean cell volume decreased ": 4.536834626904256, "Melanocytic naevus ": 5.284586953967684, "Mobility decreased ": 4.759365326516916, "Monocyte count increased ": 4.331263327736288, "Multiple system atrophy ": 31.004383141107738, "Multisystem inflammatory syndrome ": 21.133042977406035, "Musculoskeletal deformity ": 25.20263751362485, "Musculoskeletal discomfort ": 5.877989575141969, "Musculoskeletal disorder ": 6.081405235345452, "Musculoskeletal pain ": 7.100525542067282, "Musculoskeletal stiffness ": 6.346298454153795, "Myofascial pain syndrome ": 25.09936470855124, "Nasal discomfort ": 2.612436676619505, "Nasopharyngitis ": 2.0454432109076377, "Neoplasm skin ": 9.489136364530047, "Nephrostomy ": 25.874465543965314, "Nerve block ": 44.275926947221066, "Nodule ": 5.8676192756406085, "Obliterative bronchiolitis ": 22.3294370278092, "Oesophageal ulcer ": 2.264334979348395, "Onychoclasis ": 3.1066982828464145, "Oral surgery ": 13.751976031298096, "Osteoarthritis ": 5.372996052040717, "Osteomyelitis ": 2.274862927741641, "Osteosclerosis ": 8.135285920525464, "Palindromic rheumatism ": 30.61823952005552, "Panniculitis ": 57.87496223132836, "Pathological fracture ": 2.2000042427460413, "Peptic ulcer haemorrhage ": 36.7568383497984, "Peripheral swelling ": 3.373696996181063, "Pharyngeal oedema ": 6.027486491469131, "Pharyngitis ": 3.401486304602118, "Pharyngitis streptococcal ": 2.7230239674428502, "Plantar fasciitis ": 9.453008515832062, "Pleural fibrosis ": 17.93538475976761, "Pneumonia viral ": 6.379295281905739, "Polyarthritis ": 2.6168142628908115, "Post procedural complication ": 3.444012119654817, "Post procedural infection ": 4.211825732761012, "Presbyacusis ": 19.693155027798845, "Pruritus allergic ": 21.743634121495617, "Psoriasis ": 7.020498072099405, "Psoriatic arthropathy ": 4.827931991596277, "Pulmonary fibrosis ": 3.02088802227466, "Pulmonary mass ": 2.178794883435444, "Pulmonary pain ": 4.158137704256864, "Pulmonary toxicity ": 8.985311818759836, "Pustular psoriasis ": 2.0355784959623904, "Pyelonephritis ": 2.120893496059712, "Rash pruritic ": 2.874309927934957, "Red blood cell sedimentation rate abnormal ": 45.7937823890589, "Red blood cell sedimentation rate increased ": 26.98275355078131, "Renal disorder ": 2.129471149492681, "Restless legs syndrome ": 2.0043714520713967, "Retinitis ": 9.651843362267671, "Rheumatoid arthritis ": 24.13359677623724, "Rheumatoid factor negative ": 17.478297757557034, "Rheumatoid factor positive ": 7.463582862760253, "Rheumatoid lung ": 26.565900698901224, "Rheumatoid nodule ": 69.46164349701796, "Rotator cuff syndrome ": 2.221969481743316, "SAPHO syndrome ": 70.36027789015519, "Sacroiliitis ": 12.548333304250576, "Sciatica ": 2.131456938811206, "Seborrhoeic dermatitis ": 3.467001797816167, "Sensitivity to weather change ": 5.347718137703639, "Shoulder arthroplasty ": 12.7797024153782, "Sjogren's syndrome ": 6.021931312365752, "Skin necrosis ": 13.67155809032594, "Skin papilloma ": 3.629311608002093, "Skin ulcer ": 11.157963750771492, "Sleep disorder due to general medical condition, insomnia type ": 2.25174920970401, "Spinal cord infection ": 31.238532098190834, "Spinal osteoarthritis ": 4.797820786853481, "Spinal pain ": 2.1357390169729804, "Spinal stenosis ": 2.6885898959582764, "Still's disease ": 6.96323714412827, "Stress fracture ": 15.262648569195054, "Surgical failure ": 31.32323377043351, "Swelling ": 2.0744617489509505, "Swollen joint count decreased ": 664.4925987928443, "Synovial disorder ": 32.99205075254639, "Synovitis ": 29.59091849214458, "Temperature regulation disorder ": 4.137258353255031, "Tender joint count decreased ": 664.4925987928443, "Tenosynovitis ": 3.6383467405605687, "Terminal state ": 2.54361559263112, "Therapeutic product effect decreased ": 18.353715178035905, "Therapeutic product effect incomplete ": 6.292977619112028, "Therapeutic product ineffective ": 3.237458013278137, "Therapeutic response decreased ": 5.330041749263865, "Therapeutic response shortened ": 3.298332489938167, "Therapy non-responder ": 3.2225515381817025, "Toe amputation ": 2.681468550120289, "Tooth abscess ": 4.109538806857361, "Toothache ": 2.98839315604369, "Treatment failure ": 15.9850860835891, "Trigger finger ": 3.824096978500774, "Tuberculosis ": 2.732461872641268, "Ulcer ": 9.36579048076389, "Upper respiratory tract infection ": 6.038068296926785, "Varicose ulceration ": 22.3068399441898, "Vein disorder ": 6.701074541120087, "Viral infection ": 2.8276648746278634, "Viral upper respiratory tract infection ": 4.552206708749184, "Walking aid user ": 6.17933633199521, "Wheelchair user ": 3.1094182321428505, "Wrist deformity ": 97.71318189320714, "X-ray abnormal ": 8.230361510376955}
\ No newline at end of file
+{"Abortion spontaneous": 2.942096135529341, "Acute HIV infection": 193.12131468787092, "Acute kidney injury": 3.395105202732249, "Adrenal insufficiency": 3.258032587139684, "Adverse event": 3.150107791354043, "Alanine aminotransferase increased": 3.582000136693249, "Ascites": 2.9907718284534512, "Aspartate aminotransferase increased": 2.5333785524531174, "Ataxia": 2.82274568064511, "Atrial septal defect": 20.260540210180885, "Blood HIV RNA increased": 77.30947989876877, "Blood alkaline phosphatase increased": 4.357577160408731, "Blood bilirubin increased": 2.901572515512855, "Blood creatinine increased": 2.549051849328, "Blood triglycerides increased": 5.250018360232792, "Bone disorder": 4.120061661074426, "CD4 lymphocytes decreased": 24.19391661546745, "CSF HIV escape syndrome": 299.2731372212314, "Cerebellar syndrome": 23.98158578382504, "Cholestasis": 2.709380811195733, "Congenital anomaly": 6.176010083784889, "Creatinine renal clearance decreased": 10.426168998461415, "Developmental delay": 6.819118949958146, "Dilated cardiomyopathy": 8.613779352798565, "Drug interaction": 4.53382146344313, "Drug reaction with eosinophilia and systemic symptoms": 4.322025762055895, "Drug resistance": 28.68399807816939, "Encephalitis": 4.593915265610619, "Enlarged clitoris": 294.15624518269175, "Exposure during pregnancy": 5.70048580593172, "Fanconi syndrome": 23.25402452609354, "Fanconi syndrome acquired": 22.815972031634843, "Foetal exposure during pregnancy": 12.020781934089824, "Folliculitis": 2.116534192884324, "Genotype drug resistance test positive": 69.99170557169604, "Glomerular filtration rate decreased": 11.217394176131512, "Glycosuria": 38.58930676135778, "HIV infection": 46.538992949554846, "HIV test positive": 108.94046551656396, "HIV-associated neurocognitive disorder": 148.60740218812705, "Haemorrhagic diathesis": 14.743719408191971, "Hepatic function abnormal": 2.8756629219362466, "Hepatitis B": 20.994179313240178, "Hepatomegaly": 4.723320937088181, "Hepatotoxicity": 7.129990647187765, "Hyperandrogenism": 593.189358975067, "Hyperbilirubinaemia": 8.678625914807302, "Hypertriglyceridaemia": 8.325414961562897, "Hypophosphataemia": 18.33753547871697, "Immune reconstitution inflammatory syndrome": 156.74902480651065, "Immune reconstitution inflammatory syndrome associated Kaposi's sarcoma": 274.1748553756677, "Immune reconstitution inflammatory syndrome associated tuberculosis": 200.26380668698064, "Kaposi's sarcoma": 25.14681877757972, "Lactic acidosis": 4.4671318464322045, "Lipodystrophy acquired": 17.559610123437768, "Live birth": 5.471324079702918, "Low birth weight baby": 8.66007261104367, "Maternal exposure during pregnancy": 8.152203166310473, "Meningitis cryptococcal": 57.65008032027289, "Metabolic acidosis": 5.552220482419975, "Multiple organ dysfunction syndrome": 2.134475171057049, "Nephropathy toxic": 50.58966648649003, "Neuropsychological symptoms": 103.25528014840788, "No adverse event": 11.87495387159626, "Osteopenia": 4.308766513322853, "Osteoporosis": 2.154773322619436, "Pancreatitis acute": 3.033080190170774, "Pancytopenia": 2.0240553773343986, "Pathogen resistance": 43.67132036894899, "Pericardial cyst": 1588.5393538138464, "Pericardial effusion": 4.316504174223839, "Peritonitis": 4.682494025458942, "Pneumocystis jirovecii pneumonia": 8.01648309077969, "Portal hypertension": 19.21823019636772, "Premature baby": 6.460503986240286, "Premature delivery": 10.735411485505155, "Proteinuria": 6.503786909132362, "Renal disorder": 2.9066849772387493, "Renal impairment": 5.387850275683502, "Renal tubular acidosis": 28.0202350520218, "Renal tubular disorder": 12.369877000471435, "Renal tubular dysfunction": 57.13217686600649, "Renal tubular necrosis": 10.414453272042175, "Treatment failure": 5.116650058523083, "Treatment noncompliance": 11.136391395592392, "Tuberculosis": 10.76878032218702, "Varices oesophageal": 22.74528012338434, "Ventricular septal defect": 30.86111790984014, "Viral load increased": 18.884105716020542, "Viral mutation identified": 48.289062039213576, "Virologic failure": 55.0722778670858, "Weight increased": 2.0329107554446235}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/402.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/402.json
index fe414d1a7d0..4e534249b0f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/402.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/402.json
@@ -1 +1 @@
-{"Thrombocytopenia ": 34.303632273810564}
\ No newline at end of file
+{"Diarrhoea": 2.387415392560679, "Product substitution issue": 79.69252866459298}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/403.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/403.json
index 2e01a18ecf7..e867f3d1341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/403.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/403.json
@@ -1 +1 @@
-{"Malignant neoplasm progression ": 16.821220033149324}
\ No newline at end of file
+{"Abdominal distension": 2.7034248483745524, "Acute kidney injury": 5.4124060858477, "Aplasia pure red cell": 18.74988426690793, "Autonomic neuropathy": 194.14946612919385, "Blood bilirubin increased": 12.182984772246114, "Blood creatine phosphokinase increased": 3.789295374980386, "Blood creatinine increased": 6.0784234169184375, "Blood phosphorus decreased": 73.82414740774543, "Caesarean section": 26.86289957186088, "Drug resistance": 19.236133938849942, "Dysarthria": 3.73013279505712, "Fanconi syndrome acquired": 41.46213260682574, "Foetal exposure during pregnancy": 3.993836754884389, "Genotype drug resistance test positive": 232.04572794552456, "Hepatic cytolysis": 4.842451934203848, "Hepatic enzyme increased": 3.491546694019553, "Hypercholesterolaemia": 24.183076725052317, "Hyperkalaemia": 3.2487947858333595, "Hypertriglyceridaemia": 19.27069761347895, "Ileus": 27.70636651902821, "Immune reconstitution inflammatory syndrome": 297.824846055731, "Lactic acidosis": 4.626745267934338, "Liver function test abnormal": 5.552062979442419, "Maternal exposure during pregnancy": 4.4599457388284085, "Nephrolithiasis": 5.843639757490621, "Neuropathy peripheral": 3.7249766845530026, "Neurotoxicity": 24.573582278336744, "Osteonecrosis": 2.189586290976137, "Photosensitivity reaction": 15.25648437215026, "Portal hypertension": 54.101806259511264, "Potentiating drug interaction": 73.46934545318256, "Rash maculo-papular": 4.957008854912117, "Renal failure": 3.451983575293134, "Virologic failure": 45.5129816677031}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/404.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/404.json
index 8254e7caa73..e6f0cfaa2cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/404.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/404.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.04810167906518, "Alanine aminotransferase increased ": 4.843629254406811, "Anxiety ": 2.652666560137375, "Aspartate aminotransferase increased ": 7.772110674524519, "Blood lactic acid increased ": 134.77730553200527, "Death neonatal ": 478.73827759828566, "Depression suicidal ": 188.32462309535268, "Depressive symptom ": 112.08186894398936, "Diplopia ": 28.971876298800037, "Drug interaction ": 2.1382454299435274, "Dysphagia ": 9.334210902213693, "Eyelid ptosis ": 108.78052370969765, "Foetal exposure during pregnancy ": 7.100088648845284, "Haemorrhage ": 5.8560969226171045, "Hepatic steatosis ": 24.90715761283308, "Lipodystrophy acquired ": 155.41778268445293, "Mitochondrial toxicity ": 579.3875928474247, "Ophthalmoplegia ": 288.0299812836236, "Paranoia ": 49.72140767682633, "Product use in unapproved indication ": 4.010150323203283, "Psychiatric decompensation ": 296.7536430572005, "Psychomotor skills impaired ": 135.3868717632304, "Psychotic disorder ": 21.41372563484233, "Small for dates baby ": 210.3907542436804, "Suicidal ideation ": 7.090756800520585, "Tearfulness ": 126.96567792080737}
\ No newline at end of file
+{"Acute kidney injury": 2.581765815120143, "Adverse event": 8.35749858790516, "Angioedema": 7.385229777316709, "Asthenia": 7.776402662337493, "Atrial enlargement": 775.9646085531555, "Blood pressure decreased": 4.593442206143159, "Cardiac failure": 6.396540729329249, "Dehydration": 6.5586929546620985, "Disease progression": 3.262781432038645, "Gait disturbance": 4.454901184638354, "Hyperkalaemia": 6.504591346875577, "Hypotension": 4.982007338446156, "Hypovolaemia": 71.48626663745546, "N-terminal prohormone brain natriuretic peptide increased": 148.79490798639085, "Overdose": 2.644313198169167, "Pulmonary arterial pressure increased": 244.09730022711895, "Tricuspid valve incompetence": 58.410053902137946, "Urinary tract infection": 5.65841191026963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/405.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/405.json
index e6bb9db4d16..76aa2a60752 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/405.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/405.json
@@ -1 +1 @@
-{"Abdominal mass ": 37.57806414249502, "Abdominal pain lower ": 2.5522381308127624, "Abdominal tenderness ": 13.611243752053204, "Abdominal wall haematoma ": 135.36406199380917, "Abdominal wall haemorrhage ": 72.10543517281607, "Abortion ": 7.401587797330903, "Abortion induced ": 2.8466405482711528, "Abortion spontaneous ": 2.136548111081094, "Activated partial thromboplastin time prolonged ": 15.26265350376409, "Acute generalised exanthematous pustulosis ": 2.6247533865860007, "Acute hepatic failure ": 2.580484724187375, "Adrenal haemorrhage ": 77.96876009259375, "Adrenal insufficiency ": 2.244201969131368, "Anaemia ": 2.445166542078693, "Aphasia ": 2.369484532299894, "Arterial haemorrhage ": 38.35073801292001, "Blood loss anaemia ": 6.0924606814262745, "Brain herniation ": 12.238376610482664, "Bullous haemorrhagic dermatosis ": 162.27271490426335, "Caesarean section ": 5.479261196367649, "Cerebral haematoma ": 4.801119144617787, "Cerebral haemorrhage ": 4.569085711423468, "Cerebral palsy ": 25.12070892307524, "Cerebral venous thrombosis ": 10.76097528749592, "Coagulation time prolonged ": 28.40049275492769, "Coagulopathy ": 13.743694546364344, "Compartment syndrome ": 11.12417923374929, "Conjunctival haemorrhage ": 4.901895835345565, "Cyanosis ": 3.4766691810140973, "Deep vein thrombosis ": 5.708584065492969, "Dermatitis bullous ": 9.508658938620826, "Diplegia ": 6.882584813459095, "Drug-induced liver injury ": 3.8929336417149383, "Ecchymosis ": 17.79309940954364, "Embolism ": 7.1293822282274935, "Embolism venous ": 21.32796842663528, "Eosinophilia ": 2.7705884442892934, "Epistaxis ": 2.942008960374096, "Exposure during pregnancy ": 13.161807797548445, "Exposure via breast milk ": 9.158705543895335, "Extradural haematoma ": 44.1142452918582, "Fibrin D dimer increased ": 3.775207167039533, "Flank pain ": 7.2241283802444896, "Foetal death ": 2.357920615241392, "Foetal exposure during pregnancy ": 7.050663440579619, "Foetal growth restriction ": 16.376616214618622, "Foetal heart rate abnormal ": 20.51042388318696, "Gastric haemorrhage ": 3.04311381337581, "Gastrointestinal haemorrhage ": 11.994452504279923, "Gingival bleeding ": 3.9827143682713806, "Haemarthrosis ": 4.93098580283302, "Haematemesis ": 9.689882629833724, "Haematochezia ": 5.168128853245664, "Haematocrit decreased ": 3.240007182005958, "Haematoma ": 13.792405347287277, "Haematoma muscle ": 48.88352752084599, "Haematuria ": 8.627198188519179, "Haemodynamic instability ": 13.966712577101893, "Haemoglobin decreased ": 7.323738547204572, "Haemoperitoneum ": 29.423537489277283, "Haemoptysis ": 9.995659833612605, "Haemorrhage ": 12.352592852079948, "Haemorrhage intracranial ": 11.218470201155275, "Haemorrhage subcutaneous ": 44.10508653729318, "Haemorrhage urinary tract ": 9.713266419414415, "Haemorrhagic stroke ": 6.035949159890146, "Haemothorax ": 8.054653957046709, "Hemiparesis ": 5.047901729147991, "Heparin-induced thrombocytopenia ": 124.1118873726466, "Hepatic enzyme increased ": 2.753829415815492, "Hepatic function abnormal ": 4.58146862287175, "Hepatitis cholestatic ": 2.7480687808331363, "Hepatocellular injury ": 4.3368954949522, "Hyperbilirubinaemia ": 2.4641956367146447, "Hypovolaemic shock ": 22.157071704608715, "Injection site bruising ": 4.311507089019624, "Injection site haematoma ": 3.352210618876561, "Injection site haemorrhage ": 9.029096740130116, "Injection site necrosis ": 14.44022766831718, "Injection site nodule ": 6.432119677991995, "Injection site rash ": 4.27664745271828, "International normalised ratio decreased ": 4.369744797752236, "International normalised ratio increased ": 5.5782886832393945, "Intra-abdominal haematoma ": 46.468432174139, "Intra-abdominal haemorrhage ": 32.631437582704656, "Ischaemic stroke ": 2.041325858046412, "Joint dislocation ": 7.840903504745743, "Labelled drug-drug interaction issue ": 27.204020174561137, "Labelled drug-drug interaction medication error ": 16.890657382638054, "Live birth ": 8.446441254877003, "Liver injury ": 4.526313169693091, "Low birth weight baby ": 17.47392962779129, "Lower gastrointestinal haemorrhage ": 14.002127200170184, "Maternal exposure during pregnancy ": 4.166509741527456, "Melaena ": 10.122748293920669, "Mixed liver injury ": 11.652234839664258, "Mouth haemorrhage ": 4.82537450522635, "Muscle haemorrhage ": 17.850096392352537, "Necrosis ": 4.679541487408792, "Needle issue ": 3.114255613552546, "Nonreassuring foetal heart rate pattern ": 291.07510631178434, "Occult blood positive ": 18.844602033886, "Oliguria ": 4.93564172396745, "Paraplegia ": 6.782309096396426, "Pelvic haematoma ": 83.5619382405621, "Peripheral artery occlusion ": 14.159270387944304, "Petechiae ": 4.77187554756768, "Platelet count decreased ": 6.915977198353559, "Post procedural haemorrhage ": 9.704654856953672, "Posterior reversible encephalopathy syndrome ": 3.1589555388102832, "Pre-eclampsia ": 5.851918563562781, "Premature baby ": 10.370539212061937, "Premature delivery ": 6.692908556746825, "Premature labour ": 6.236331815874247, "Procedural haemorrhage ": 19.80962190286255, "Product prescribing issue ": 5.362835264440401, "Prosthetic cardiac valve thrombosis ": 299.5312729577975, "Prothrombin time prolonged ": 10.550206288224688, "Pulmonary alveolar haemorrhage ": 5.429051976734282, "Pulmonary embolism ": 4.808955317205691, "Pulmonary haemorrhage ": 5.891293067287945, "Purpura ": 4.228419939763872, "Rash maculo-papular ": 3.0293452941722783, "Rectal haemorrhage ": 2.61199365365973, "Respiratory tract haemorrhage ": 26.958344887025344, "Retroperitoneal haematoma ": 108.03102825230611, "Retroperitoneal haemorrhage ": 34.69276445919441, "Sensory loss ": 2.4512796741872647, "Shock ": 2.362132501261065, "Shock haemorrhagic ": 23.631444096834187, "Sinus tachycardia ": 3.452923163483174, "Skin haemorrhage ": 3.4174868880049534, "Skin lesion ": 2.6470272167276545, "Skin necrosis ": 17.228081001423956, "Spinal epidural haematoma ": 23.772728495031576, "Spinal epidural haemorrhage ": 315.80309364596945, "Spontaneous haematoma ": 8.301848461482928, "Subarachnoid haemorrhage ": 3.862276025776406, "Subcutaneous haematoma ": 15.118830384412425, "Subdural haematoma ": 10.969171664236264, "Subdural haemorrhage ": 12.60754683840096, "Tachypnoea ": 3.767979817967928, "Talipes ": 6.548371931157626, "Tenderness ": 2.291590807787024, "Thrombocytopenia ": 4.5849483169663685, "Thrombocytosis ": 7.780007914275118, "Thrombosis ": 3.037490213944926, "Toxic epidermal necrolysis ": 4.01159651663125, "Transaminases increased ": 3.3030469967884937, "Type I hypersensitivity ": 4.01648118204852, "Type IV hypersensitivity reaction ": 11.183205358346154, "Upper gastrointestinal haemorrhage ": 33.35345022945278, "Vaginal haemorrhage ": 2.632437635088713, "Venous thrombosis ": 6.836357549358131}
\ No newline at end of file
+{"Abscess": 2.1441600950393678, "Adverse drug reaction": 5.67063554754995, "Alanine aminotransferase increased": 3.309882720048668, "Allergic oedema": 6.790035003120996, "Alopecia": 2.648858619147889, "Amyotrophic lateral sclerosis": 3.62471799970405, "Ankylosing spondylitis": 7.836217888321912, "Anticipatory anxiety": 249.74425441225355, "Antinuclear antibody positive": 2.528105480790253, "Apparent death": 6.293770880227515, "Appendix disorder": 8.851929051093096, "Arteriospasm coronary": 2.427378200962125, "Arthritis": 3.9782962012870393, "Arthritis bacterial": 3.0330760683879, "Arthritis infective": 3.883871485230878, "Arthrodesis": 14.803946389568535, "Arthropathy": 7.197340132974272, "Arthropod bite": 3.054132312708799, "Aspartate aminotransferase increased": 3.5917888079459237, "Basal cell carcinoma": 19.77686439695485, "Bipolar disorder": 5.952575556198846, "Blood creatinine decreased": 3.698381054108359, "Blood magnesium increased": 8.455616686934539, "Blood parathyroid hormone decreased": 73.9334437838053, "Bone cyst": 9.492195216567929, "Bone erosion": 12.29258069706092, "Bone hypertrophy": 28.90035236619756, "Breast abscess": 9.429902283120557, "Bronchitis chronic": 14.566823397579366, "Bursitis": 2.160150352365332, "Butterfly rash": 5.182006794659711, "C-reactive protein abnormal": 21.495197759273097, "C-reactive protein decreased": 33.206599961683715, "C-reactive protein increased": 5.594122253263659, "Carpal tunnel syndrome": 7.302437944713624, "Cartilage injury": 5.073506918295278, "Coeliac disease": 3.14337702426625, "Condition aggravated": 3.382582241956854, "Contraindicated product administered": 13.427607887308238, "Contrast media allergy": 46.37452397507285, "Crohn's disease": 2.5490366837758813, "Cyst": 2.80734461975285, "Dactylitis": 26.82559128909287, "Deafness neurosensory": 2.11146654097991, "Deformity": 3.6300099198008544, "Demyelination": 2.6716017515131005, "Dental caries": 2.9726413582842217, "Dermatitis allergic": 4.666109238538444, "Disability": 2.6446755302296987, "Diverticulitis": 3.0513563184282013, "Drug eruption": 5.3241083865180485, "Drug hypersensitivity": 10.055935079953366, "Drug ineffective": 5.962459342945414, "Drug intolerance": 12.3794681353462, "Drug tolerance": 3.5955307219698853, "Drug tolerance decreased": 16.551201998619682, "Drug use disorder": 28.33158551255392, "Dry eye": 3.450327203075469, "Elbow deformity": 55.1817012853659, "Enthesopathy": 10.64618368202364, "Epicondylitis": 3.693440757446758, "Epigastric discomfort": 2.0148652200839265, "Episcleritis": 11.975934621469198, "Exostosis": 2.977859028139469, "Eye disorder": 2.8678700039787985, "Eye operation": 5.336320250511881, "Fat necrosis": 21.98083171647188, "Fear of injection": 11.71110555400744, "Femur fracture": 5.1409521457003375, "Fibromyalgia": 5.43304050658926, "Fine motor skill dysfunction": 4.365088791203441, "Finger deformity": 14.070033069174912, "Foetal death": 2.756097755791045, "Food allergy": 6.069751740822659, "Foot deformity": 8.968887827127846, "Frustration tolerance decreased": 4.000052796429732, "Gait inability": 3.1116297560662014, "Gastrointestinal disorder": 2.0720774043844528, "Gastrointestinal inflammation": 3.051195567808402, "Gastrointestinal toxicity": 17.68575744113546, "Goitre": 2.961113723684197, "Granuloma skin": 73.05270481868115, "Grip strength decreased": 3.4561394243357157, "HLA marker study positive": 123.38315335318828, "Hepatic enzyme abnormal": 3.4898519713409897, "Hepatic enzyme increased": 3.252871898794369, "Hepatic fibrosis": 10.103968838474696, "Hepatotoxicity": 4.823787832979731, "Herpes ophthalmic": 3.0600379710161505, "Hip arthroplasty": 2.251945628693864, "Hip surgery": 2.414197114852868, "Hypercalcaemia": 14.239782167196635, "Hypercholesterolaemia": 3.9040582303196114, "Hypersensitivity": 2.087173745827284, "Hypersensitivity vasculitis": 13.919752633654966, "Immobile": 4.820566533687059, "Immune system disorder": 3.0209059794743425, "Immunodeficiency": 8.672808674801876, "Immunosuppression": 2.353486226874941, "Impaired healing": 2.777814458372898, "Impaired work ability": 3.854267387592981, "Increased tendency to bruise": 2.698544130869559, "Infection": 3.255496063287737, "Inflammation": 7.738638703936859, "Infusion related reaction": 5.352965162285789, "Infusion site reaction": 3.996412962877269, "Injection site bruising": 7.89755440015157, "Injection site discolouration": 3.815697470155639, "Injection site hypersensitivity": 2.5969490375590483, "Injection site rash": 3.4023140761041013, "Injection site reaction": 2.5244079279319647, "Injection site urticaria": 3.199727397659597, "Injection site vesicles": 2.64432819183644, "Intervertebral disc disorder": 12.60873720505488, "Intervertebral disc protrusion": 3.0587858059283097, "Intestinal sepsis": 26.293646695383604, "Intra-abdominal fluid collection": 4.907420254631859, "Iritis": 2.097789978121071, "Joint arthroplasty": 4.517778103469709, "Joint destruction": 10.222374383493202, "Joint effusion": 3.557999372806435, "Joint injury": 19.635145082222294, "Joint laxity": 30.53168598296857, "Joint lock": 3.236007646610801, "Joint noise": 3.3578727614982995, "Joint range of motion decreased": 7.707353596568366, "Joint stiffness": 7.434920151720329, "Joint swelling": 11.448231661132752, "Joint warmth": 6.113449167434034, "Juvenile idiopathic arthritis": 4.088592319942951, "Knee arthroplasty": 9.160917505316515, "Knee deformity": 6.471926786740402, "Kyphoscoliosis": 84.51759346296382, "Laboratory test abnormal": 2.0097854070366075, "Latent tuberculosis": 17.4789889343654, "Limb deformity": 4.48556929796773, "Lipoma": 2.5075098067351163, "Liver disorder": 4.618949909791152, "Liver function test increased": 2.017792734592747, "Localised infection": 3.8777537447625474, "Loss of personal independence in daily activities": 4.698868130929229, "Lower respiratory tract infection": 3.809324193818004, "Lupus-like syndrome": 3.5868098804436146, "Lymphoma": 3.493247850193469, "Malignant melanoma": 2.272604208523304, "Mass excision": 21.853021160873944, "Mean cell volume decreased": 4.528331547241872, "Melanocytic naevus": 5.274682234066263, "Mobility decreased": 4.750443344486641, "Monocyte count increased": 4.323145414416083, "Multiple system atrophy": 30.94627366493956, "Multisystem inflammatory syndrome": 21.0934345137957, "Musculoskeletal deformity": 25.15540203315701, "Musculoskeletal discomfort": 5.866971795620636, "Musculoskeletal disorder": 6.068370078237419, "Musculoskeletal pain": 7.087215249747964, "Musculoskeletal stiffness": 6.334400340437233, "Myofascial pain syndrome": 25.052321193395933, "Nasal discomfort": 2.6075402596629886, "Nasopharyngitis": 2.041452454614139, "Neoplasm skin": 9.47135129732481, "Nephrostomy": 25.82597090812718, "Nerve block": 44.19294169055031, "Nodule": 5.856621075972264, "Obliterative bronchiolitis": 22.287584952359467, "Oesophageal ulcer": 2.2600910718574974, "Onychoclasis": 3.1008755414485925, "Oral surgery": 13.726201461261349, "Osteoarthritis": 5.3629243042662935, "Osteomyelitis": 2.2705991635854263, "Osteosclerosis": 8.120038451470144, "Palindromic rheumatism": 30.56085376519544, "Panniculitis": 57.766475810893695, "Pathological fracture": 2.1958808983577525, "Peptic ulcer haemorrhage": 36.68794421085611, "Peripheral swelling": 3.3673719914281963, "Pharyngeal oedema": 6.016188791196708, "Pharyngitis": 3.394320856624504, "Pharyngitis streptococcal": 2.7179203669150285, "Plantar fasciitis": 9.435290899187736, "Pleural fibrosis": 17.901769037737374, "Pneumonia viral": 6.367338702120551, "Polyarthritis": 2.611909613285425, "Post procedural complication": 3.4375570425540234, "Post procedural infection": 4.203931639178593, "Presbyacusis": 19.65624519239521, "Pruritus allergic": 21.70287979022532, "Psoriasis": 7.007337123580148, "Psoriatic arthropathy": 4.8531263201646935, "Pulmonary fibrosis": 3.015225721887317, "Pulmonary mass": 2.174711136073681, "Pulmonary pain": 4.150344048008377, "Pulmonary toxicity": 8.968469862417994, "Pustular psoriasis": 2.031763340781198, "Pyelonephritis": 2.116918341867629, "Rash pruritic": 2.86892190388931, "Red blood cell sedimentation rate abnormal": 45.70794230793286, "Red blood cell sedimentation rate increased": 26.93217104467422, "Renal disorder": 2.125164269368896, "Restless legs syndrome": 2.000614616833089, "Retinitis": 9.633753311094074, "Rheumatoid arthritis": 24.088334555396862, "Rheumatoid factor negative": 17.445539103306672, "Rheumatoid factor positive": 7.449593170170464, "Rheumatoid lung": 26.516109430127504, "Rheumatoid nodule": 69.33143999834049, "Rotator cuff syndrome": 2.217804877003217, "SAPHO syndrome": 70.22840626655307, "Sacroiliitis": 12.524814151181609, "Sciatica": 2.1274619356670703, "Seborrhoeic dermatitis": 3.460503818133671, "Sensitivity to weather change": 5.337695048312534, "Shoulder arthroplasty": 12.755749580623633, "Sjogren's syndrome": 6.010644337283739, "Skin necrosis": 13.645931659907186, "Skin papilloma": 3.62250935697878, "Skin ulcer": 11.137047623560418, "Sleep disorder due to general medical condition, insomnia type": 2.2475288067219874, "Spinal cord infection": 31.179982722865173, "Spinal osteoarthritis": 4.788828145028314, "Spinal pain": 2.1317359698278544, "Spinal stenosis": 2.683550732594421, "Still's disease": 6.950186298841065, "Stress fracture": 15.234041501215229, "Surgical failure": 31.26452681252403, "Swelling": 2.078037639407465, "Swollen joint count decreased": 663.2472231461189, "Synovial disorder": 32.93021528612962, "Synovitis": 29.535440842173998, "Temperature regulation disorder": 4.1295037901516976, "Tender joint count decreased": 663.2472231461189, "Tenosynovitis": 3.6315275324338416, "Terminal state": 2.538848227959197, "Therapeutic product effect decreased": 18.31930353388568, "Therapeutic product effect incomplete": 6.281179990168475, "Therapeutic product ineffective": 3.2313901950431805, "Therapeutic response decreased": 5.320050389817578, "Therapeutic response shortened": 3.2921505274903216, "Therapy non-responder": 3.2162275213348286, "Toe amputation": 2.6764428343948503, "Tooth abscess": 4.101836350581312, "Toothache": 2.982791893053795, "Treatment failure": 15.955114400089617, "Trigger finger": 3.8169296896928175, "Tuberculosis": 2.727340379548888, "Ulcer": 9.34823513632258, "Upper respiratory tract infection": 6.026749957197957, "Varicose ulceration": 22.2650318352459, "Vein disorder": 6.688514713383858, "Viral infection": 2.822364790747432, "Viral upper respiratory tract infection": 4.543674782510658, "Walking aid user": 6.167754469016563, "Wheelchair user": 3.103590403158679, "Wrist deformity": 97.53003668769182, "X-ray abnormal": 8.214935787937405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/406.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/406.json
index 494bbcd05b6..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/406.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/406.json
@@ -1 +1 @@
-{"Agitation ": 3.0136677209233658, "Akinesia ": 90.16038367664906, "Balance disorder ": 4.513355337336894, "Behaviour disorder ": 7.937667586832355, "Blood creatine phosphokinase increased ": 4.588567024552758, "Bradykinesia ": 56.495550805304994, "Chromaturia ": 10.166329997854277, "Cognitive disorder ": 5.504113140833774, "Colitis microscopic ": 39.93642886008693, "Compulsive shopping ": 140.37564444815737, "Constipation ": 2.369206381252729, "Delirium ": 2.3457006208151205, "Delusion ": 32.72418609728828, "Dementia ": 5.7229377599229245, "Depressed level of consciousness ": 2.157269882727704, "Dopamine dysregulation syndrome ": 672.2742716305228, "Drug abuse ": 2.378851309861442, "Drug withdrawal syndrome ": 4.927621321142853, "Dyskinesia ": 63.78020925244957, "Dysphagia ": 6.151914750372951, "Dysphonia ": 2.1097123571783083, "Dystonia ": 30.165469395079832, "Eating disorder ": 7.421471110924092, "Fall ": 2.713076180565758, "Gait disturbance ": 5.715473017294619, "Gambling disorder ": 151.69592192483438, "General physical health deterioration ": 2.4877322067064656, "Hallucination ": 8.190409346291263, "Hallucination, visual ": 30.772711995753465, "Hypersexuality ": 165.4767100254095, "Hyperthermia ": 7.379196534772826, "Hypokinesia ": 12.360679957870936, "Hypomania ": 18.694912954293475, "Hyponatraemia ": 3.0186994814974075, "Impulse-control disorder ": 92.71688525003526, "Impulsive behaviour ": 51.4465266678604, "Incorrect dose administered ": 2.009071232631149, "Irritability ": 4.337991242353828, "Loss of personal independence in daily activities ": 2.369763036930724, "Motor dysfunction ": 29.35575909122322, "Movement disorder ": 3.3393979533287625, "Muscle rigidity ": 29.85303263033005, "Musculoskeletal stiffness ": 3.854784034248912, "Mydriasis ": 10.946730025066095, "Neuroleptic malignant syndrome ": 19.767517285193183, "Nightmare ": 3.683581612399953, "On and off phenomenon ": 624.7224564583022, "Oromandibular dystonia ": 258.7186522340258, "Orthostatic hypotension ": 8.658713159599381, "Parkinson's disease ": 89.26674060586625, "Parkinsonian gait ": 195.87889138105592, "Parkinsonism ": 25.524049144938555, "Persecutory delusion ": 28.811704935331065, "Pollakiuria ": 3.1450774877689414, "Psychomotor hyperactivity ": 8.649524864319838, "Quality of life decreased ": 10.613974978487114, "Respiratory failure ": 2.269930607267564, "Resting tremor ": 234.97208418261712, "Restlessness ": 2.3832442306222785, "Rhabdomyolysis ": 3.907979611635122, "Therapeutic response shortened ": 174.86863291804755, "Treatment noncompliance ": 3.288600916973963, "Tremor ": 2.879850505920309, "Urinary incontinence ": 4.874628567359238, "Urinary retention ": 3.306935925816632, "Wrong technique in product usage process ": 2.7074472992354206}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/407.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/407.json
index a6fccc45f29..075ce6923b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/407.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/407.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 3.2826850280997317, "Acute hepatic failure ": 10.783547155231188, "Alanine aminotransferase increased ": 9.492754356043614, "Aspartate aminotransferase increased ": 4.788736362466789, "Blood HIV RNA decreased ": 1119.2050576317483, "Blood bilirubin increased ": 5.079653263444774, "Blood creatine phosphokinase increased ": 5.632796378609466, "Blood creatinine increased ": 7.8563184200077245, "Blood phosphorus decreased ": 78.1716564135315, "Bone pain ": 5.983482777487846, "Creatinine renal clearance decreased ": 20.202244273293964, "Drug ineffective ": 3.7963074871229097, "Drug resistance ": 109.3203281592032, "Fanconi syndrome acquired ": 18.472107891819284, "Hepatic cancer ": 8.954113847391804, "Hepatic cirrhosis ": 17.91011149176656, "Hepatic enzyme increased ": 2.0664092384616937, "Hepatic failure ": 5.241794303683563, "Hepatic function abnormal ": 3.891896903411976, "Hepatitis B ": 113.90205205799128, "Hepatitis B DNA increased ": 398.5147792574245, "Hepatitis B reactivation ": 137.78668538384193, "Hepatocellular carcinoma ": 9.974535134057517, "Hypophosphataemia ": 83.70592078534567, "Jaundice ": 5.625254493717801, "Lactic acidosis ": 6.878527305442215, "Multiple-drug resistance ": 19.48396269195553, "Osteomalacia ": 48.0659823795009, "Pathogen resistance ": 39.47302722295338, "Periorbital swelling ": 21.459340586837158, "Platelet count decreased ": 2.592392256979099, "Pregnancy ": 18.56908384486345, "Protein urine present ": 42.48409458101086, "Proteinuria ": 6.678567825246477, "Rash maculo-papular ": 2.4812485812290936, "Renal impairment ": 5.902828834539954, "Rhabdomyolysis ": 3.788695308583685, "Skin plaque ": 14.51597262873656, "Swelling face ": 2.182795241707037, "Therapeutic response decreased ": 6.628839912534524, "Thrombocytopenia ": 2.1677032251895287, "Transaminases increased ": 3.805537940140349, "Treatment noncompliance ": 4.781881495143108, "Viral load increased ": 102.31203578379056, "Viral mutation identified ": 71.60971291362493, "Virologic failure ": 57.82476222836497}
\ No newline at end of file
+{"Thrombocytopenia": 34.30040556249768}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/408.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/408.json
index e33d76056aa..788570cd8ff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/408.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/408.json
@@ -1 +1 @@
-{"Activated partial thromboplastin time prolonged ": 2.617762956053923, "Acute kidney injury ": 5.707418540045119, "Acute pulmonary oedema ": 9.137260959862836, "Akinesia ": 4.05736747784321, "Amyloidosis ": 7.154680796279707, "Angioedema ": 8.961703665004547, "Anuria ": 4.921701033935137, "Aortic stenosis ": 3.4958651742543574, "Aortic valve calcification ": 17.68778272181648, "Aortic valve incompetence ": 9.979374345995724, "Arrhythmic storm ": 20.15894567754527, "Arterial haemorrhage ": 5.577796016698047, "Asthma-chronic obstructive pulmonary disease overlap syndrome ": 18.042183582852, "Atrial enlargement ": 21.46485247400659, "Atrial fibrillation ": 3.7706376588443553, "Atrial flutter ": 3.9373078428742767, "Atrioventricular block ": 2.6746104957443557, "Atrioventricular block first degree ": 3.1617787388566314, "Azotaemia ": 3.160396016433929, "Bleeding time prolonged ": 5.182148408632219, "Blood chloride decreased ": 4.229118504721679, "Blood chloride increased ": 16.278540927303148, "Blood creatine increased ": 13.36585830485748, "Blood creatinine abnormal ": 3.678835301739419, "Blood creatinine decreased ": 2.5258460839354218, "Blood creatinine increased ": 9.478057482141944, "Blood iron decreased ": 3.172002068758169, "Blood phosphorus increased ": 4.185427107854594, "Blood potassium abnormal ": 4.0394517099962135, "Blood potassium decreased ": 2.6413713536654835, "Blood potassium increased ": 29.696279267929608, "Blood pressure abnormal ": 5.915922562817076, "Blood pressure decreased ": 9.148640312502266, "Blood pressure diastolic decreased ": 5.326675410249894, "Blood pressure fluctuation ": 2.816196528686957, "Blood pressure systolic abnormal ": 5.338238989462096, "Blood pressure systolic decreased ": 47.24903908371801, "Blood pressure systolic increased ": 3.821362865648435, "Blood sodium decreased ": 4.038709982335565, "Blood triglycerides increased ": 3.1193379666092924, "Blood urea increased ": 9.26840210392079, "Blood urea nitrogen/creatinine ratio increased ": 14.509370548118682, "Blood uric acid increased ": 5.993897309208055, "Body mass index decreased ": 58.2699137992591, "Brain natriuretic peptide abnormal ": 31.065263152780187, "Brain natriuretic peptide increased ": 22.80125123847497, "Breath sounds abnormal ": 3.007565562611109, "Bronchial hyperreactivity ": 7.795532045927324, "Bundle branch block left ": 11.71035244551503, "Cardiac disorder ": 2.196983400708476, "Cardiac dysfunction ": 23.83435988466822, "Cardiac failure ": 19.2762280312126, "Cardiac failure acute ": 13.252002112572542, "Cardiac failure chronic ": 37.40315701387538, "Cardiac failure congestive ": 3.197487178637858, "Cardiac function test abnormal ": 51.483650746269966, "Cardiac murmur ": 2.148472368833928, "Cardiac output decreased ": 9.904013835479198, "Cardiac ventricular disorder ": 26.397360822912308, "Cardiac ventricular thrombosis ": 2.868965788929204, "Cardiogenic shock ": 8.206561567190434, "Cardiomegaly ": 3.8053994364115713, "Cardiomyopathy ": 7.454447152644716, "Cardiorenal syndrome ": 48.39212622070965, "Cardiovascular insufficiency ": 3.683105492181041, "Computerised tomogram heart abnormal ": 83.59527123745303, "Concomitant disease aggravated ": 4.149549186116058, "Congestive hepatopathy ": 8.384737529573558, "Contraindicated product administered ": 6.692959633049774, "Cough ": 2.4542329062700814, "Craniocerebral injury ": 4.222639285865616, "Creatinine renal clearance decreased ": 3.23681990328769, "Creatinine renal clearance increased ": 5.73173930702683, "Death ": 2.4896024292829377, "Dehydration ": 2.7876152752050283, "Dementia ": 2.07362891943684, "Device inappropriate shock delivery ": 245.0806903727404, "Diastolic dysfunction ": 14.840339271146098, "Dilatation atrial ": 13.473400645138348, "Dilated cardiomyopathy ": 14.265133013679788, "Dizziness postural ": 4.6962221369103645, "Dyslipidaemia ": 3.799857783534837, "Dyspnoea at rest ": 6.922070749485373, "Dyspnoea exertional ": 2.944505933026446, "Dyspnoea paroxysmal nocturnal ": 19.07967881430109, "Ejection fraction ": 6.896740868282619, "Ejection fraction abnormal ": 35.7475720262455, "Ejection fraction decreased ": 32.600404703756325, "Electrocardiogram ST segment elevation ": 3.4663151846904494, "Electrocardiogram T wave inversion ": 6.10130576216825, "Electrocardiogram abnormal ": 2.6627722430024354, "Erysipelas ": 2.421818471548661, "Essential hypertension ": 3.5948513258117534, "Exercise tolerance decreased ": 3.177245322363361, "Faeces hard ": 2.565934927019133, "Feeling abnormal ": 2.097388170792456, "Fluid intake reduced ": 5.647244532364818, "Fluid retention ": 4.289573985110072, "General physical condition abnormal ": 4.123896193324312, "General physical health deterioration ": 2.3548803371662985, "Glomerular filtration rate abnormal ": 4.997079519827066, "Glomerular filtration rate decreased ": 35.55669847920228, "Glomerular filtration rate increased ": 9.25722964247403, "Gout ": 4.925266766803385, "Gynaecomastia ": 4.515124351117639, "Haematocrit decreased ": 3.153285875838852, "Haemoglobin increased ": 3.014614820253325, "Head injury ": 2.1249779247579745, "Heart failure with preserved ejection fraction ": 30.516256251498195, "Heart failure with reduced ejection fraction ": 56.69108818540332, "Heart rate abnormal ": 4.122690429358669, "Heart rate decreased ": 4.860297003144631, "Heart rate irregular ": 3.0873467514235187, "High density lipoprotein decreased ": 13.061225053515928, "Hyperkalaemia ": 19.19636968435838, "Hypertensive heart disease ": 12.308155954952712, "Hypervolaemia ": 9.188865675520768, "Hypochromasia ": 110.26949182621678, "Hypokinesia ": 3.0643111319493146, "Hypotension ": 15.414840668493111, "Hypovolaemia ": 6.750063890942708, "Hypovolaemic shock ": 2.0526053614482795, "Implantable defibrillator insertion ": 7.521236884866854, "Inappropriate schedule of product administration ": 3.678077890179571, "Incorrect dosage administered ": 2.2431440202247144, "Incorrect dose administered ": 2.03495480429601, "Infarction ": 2.5990211841000885, "International normalised ratio abnormal ": 2.113247653499666, "International normalised ratio fluctuation ": 5.142195874885386, "Ischaemic cardiomyopathy ": 19.16912200475098, "Ischaemic hepatitis ": 10.09415479386784, "Left atrial dilatation ": 13.847323651152758, "Left atrial enlargement ": 30.113201636170395, "Left ventricular dilatation ": 26.345040155626634, "Left ventricular dysfunction ": 16.764707657584573, "Left ventricular enlargement ": 67.98384027123443, "Left ventricular failure ": 3.863290671981001, "Left ventricular hypertrophy ": 6.928718050347364, "Lip swelling ": 4.290892154531568, "Lymphocyte count decreased ": 2.484464169302409, "Lymphocyte percentage decreased ": 6.499894652432314, "Mean platelet volume increased ": 43.03522717998387, "Meniscus injury ": 2.832516971038215, "Mitral valve incompetence ": 12.87866634901938, "Mitral valve thickening ": 147.5725274569521, "Myocardial infarction ": 2.363289624422017, "Myocardial ischaemia ": 2.1172057876936594, "N-terminal prohormone brain natriuretic peptide increased ": 100.90825695767376, "Nasal pruritus ": 5.141645180688413, "Near death experience ": 15.058884646759312, "Neutrophil count increased ": 3.0112822457471373, "Nipple pain ": 3.6366776258785545, "Nocturia ": 2.5170997443812606, "Normochromic anaemia ": 13.617549779275077, "Oedema ": 3.962296584273642, "Oedema peripheral ": 3.797685865757976, "Oliguria ": 2.3769549331181525, "Orthopnoea ": 22.99954149103805, "Orthostatic hypotension ": 6.107235749936124, "Pollakiuria ": 2.604135152429276, "Polyuria ": 5.092098920893879, "Prerenal failure ": 4.001117735199706, "Prescribed underdose ": 12.828336572077127, "Product monitoring error ": 11.71672629759177, "Product prescribing error ": 7.364862618951516, "Product use in unapproved indication ": 2.26039730538447, "Pruritus ": 2.2049266412573343, "Pulmonary congestion ": 4.078697337071549, "Pulmonary function test abnormal ": 5.357829792949751, "Pulmonary hypertension ": 3.667162414004477, "Pulmonary oedema ": 3.815517905871005, "Radius fracture ": 4.409715182969413, "Rales ": 5.769772770862655, "Red cell distribution width increased ": 11.609380249174064, "Renal disorder ": 3.146799927914082, "Renal failure ": 4.468865087174, "Renal function test abnormal ": 5.806817070336124, "Renal impairment ": 9.955752740250624, "Right atrial enlargement ": 21.581307794944863, "Right ventricular dysfunction ": 9.651148461207525, "SARS-CoV-2 test ": 27.96750828522805, "Scan myocardial perfusion ": 363.8191432832047, "Sinus bradycardia ": 3.0761555731222883, "Sudden cardiac death ": 9.954921975853894, "Sudden death ": 5.656351127387332, "Swelling face ": 2.654290262407296, "Swollen tongue ": 3.5034004295996666, "Systolic dysfunction ": 11.076860304589946, "Throat clearing ": 17.351382960204543, "Traumatic intracranial haemorrhage ": 8.014231865138628, "Tricuspid valve incompetence ": 11.18877834642918, "Underdose ": 7.808026541715906, "Upper respiratory tract inflammation ": 7.829788801541455, "Urine output decreased ": 4.677211542612704, "Urine output increased ": 4.504381016562586, "Vasoplegia syndrome ": 8.429467771479342, "Vein disorder ": 2.562815872808366, "Venous pressure jugular decreased ": 162.2718563149147, "Venous pressure jugular increased ": 35.229315701683525, "Ventricular arrhythmia ": 4.719421345014501, "Ventricular extrasystoles ": 5.12228443675819, "Ventricular fibrillation ": 3.982400600795079, "Ventricular hyperkinesia ": 86.58848158698123, "Ventricular hypokinesia ": 5.468852504959744, "Ventricular tachycardia ": 8.380094961380163, "Viral diarrhoea ": 57.868689420113824, "Weight fluctuation ": 8.420773088242267, "Weight increased ": 2.5407256681916643, "Wrong technique in product usage process ": 13.034081218463443}
\ No newline at end of file
+{"Malignant neoplasm progression": 16.821220033149324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/409.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/409.json
index 02b94bdae5b..a9f2a7dd5a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/409.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/409.json
@@ -1 +1 @@
-{"Abdominal abscess ": 11.885365636094624, "Abdominal distension ": 2.6594084829990634, "Abdominal pain ": 2.8281156138463266, "Abdominal pain lower ": 2.6215047175648385, "Abnormal faeces ": 5.567865820834672, "Abortion spontaneous ": 3.2589633691132947, "Abscess ": 9.92959164608, "Abscess intestinal ": 34.78200113140713, "Acne ": 4.775239499533394, "Adenocarcinoma of colon ": 13.491180964646931, "Adverse drug reaction ": 2.8201032404689097, "Anal abscess ": 46.87329115799282, "Anal fissure ": 15.457887635142932, "Anal fistula ": 37.930542835594586, "Anal incontinence ": 4.069630284296669, "Anal inflammation ": 22.93618007380296, "Anal ulcer ": 16.063526203084294, "Ankylosing spondylitis ": 4.701029525624019, "Anorectal discomfort ": 7.912944950868469, "Anorectal disorder ": 12.5020718549913, "Appendicitis ": 4.494765027478689, "Arthritis ": 2.1650567359660524, "Autoimmune haemolytic anaemia ": 2.624947056212548, "B-cell lymphoma ": 4.318384569045144, "Bacillus infection ": 102.88609375192576, "Bacterial vulvovaginitis ": 220.71514649729505, "Blood iron decreased ": 4.058160068064939, "Bowel movement irregularity ": 6.072757220540931, "Breast cancer female ": 2.0726610378330133, "Breast cancer stage II ": 3.2361674379192857, "C-reactive protein increased ": 2.044240116602396, "Calcium deficiency ": 20.190796838059963, "Cataract ": 2.1130708822086794, "Cellulitis ": 2.261045036874991, "Central obesity ": 51.167153941902775, "Cholangitis ": 2.340651189596253, "Cholangitis sclerosing ": 31.794912798096867, "Cholecystectomy ": 2.7440029379404693, "Clostridium difficile infection ": 12.701249913690836, "Colectomy ": 54.76873175522815, "Colitis ": 6.307296503352374, "Colitis ulcerative ": 71.68411751356084, "Colon cancer ": 3.0378295529586, "Colonic abscess ": 25.91822610262592, "Condition aggravated ": 2.03123802190726, "Coronavirus infection ": 2.351810579779401, "Crohn's disease ": 43.6110062316749, "Cushingoid ": 16.90867591670899, "Cutaneous vasculitis ": 3.0080387529807835, "Cytomegalovirus colitis ": 8.801311563677947, "Cytomegalovirus enterocolitis ": 17.604648125731924, "Cytomegalovirus infection ": 4.111266563308093, "Defaecation urgency ": 38.80902748119965, "Device leakage ": 3.0842280594774034, "Diarrhoea haemorrhagic ": 17.850853444535716, "Dislocation of vertebra ": 2.890839680098303, "Drug effect less than expected ": 18.34997703813664, "Drug hypersensitivity ": 2.294126974687248, "Drug ineffective ": 2.553676136961116, "Drug level below therapeutic ": 4.904884013450886, "Drug level decreased ": 17.02778537103065, "Drug specific antibody present ": 47.27323205432713, "Dyschezia ": 12.19528821152895, "Ear infection ": 3.068968007253585, "Eastern Cooperative Oncology Group performance status worsened ": 9.53971939204578, "Enteritis ": 6.37977261619378, "Enteritis infectious ": 9.829030077610696, "Enterocutaneous fistula ": 26.70261704398224, "Eosinophilic pneumonia ": 3.9585279144011016, "Epstein-Barr virus infection ": 3.101855321832678, "Erythema nodosum ": 11.648051388012092, "Escherichia infection ": 9.096285215324576, "Faecal calprotectin abnormal ": 87.0223080114107, "Faecal calprotectin increased ": 76.9701781326249, "Faeces hard ": 5.766441460172619, "Faeces soft ": 11.18530217537436, "Female genital tract fistula ": 2.098364443008101, "Fistula ": 21.336964819544228, "Flatulence ": 4.684183963464483, "Frequent bowel movements ": 28.086848544392943, "Furuncle ": 12.67254366788747, "Gastroenteritis eosinophilic ": 30.839229154454127, "Gastroenteritis viral ": 2.3124727748613227, "Gastrointestinal infection ": 4.301088094830861, "Gastrointestinal inflammation ": 19.3713413801621, "Gastrointestinal mucosa hyperaemia ": 46.57399219960523, "Gastrointestinal pain ": 2.313433448755051, "Gastrointestinal ulcer ": 17.236869574978247, "Gastrointestinal wall thickening ": 24.172254056166583, "General symptom ": 7.037574120874548, "Granuloma ": 3.609249612532609, "Haematochezia ": 11.757112570471056, 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9.287204766367726, "Intestinal perforation ": 2.1917088487797582, "Intestinal resection ": 33.802855059443964, "Intestinal stenosis ": 59.98262235847874, "Intestinal ulcer ": 16.303260633182845, "Iron deficiency ": 7.687127818665867, "JC polyomavirus test positive ": 37.41776843719308, "Large intestinal stenosis ": 38.98175621252901, "Large intestinal ulcer ": 11.661997530901298, "Large intestine perforation ": 3.0286660965271777, "Large intestine polyp ": 4.29907206738235, "Liver abscess ": 4.679804849207558, "Loss of therapeutic response ": 70.2541207970881, "Lower respiratory tract infection ": 2.8379438517107607, "Lupus-like syndrome ": 11.815927657211178, "Malnutrition ": 3.182103693668411, "Maternal exposure during breast feeding ": 2.114787289082662, "Mouth ulceration ": 3.5568019443972068, "Mucous stools ": 46.74572706225303, "Nasopharyngitis ": 3.1134567434864557, "Nipple pain ": 4.679804849207558, "Off label use ": 4.022212075234344, "Organising pneumonia ": 3.442931792742111, "Overgrowth bacterial ": 56.09709914828749, "Pharyngitis ": 2.016090287879069, "Pharyngitis streptococcal ": 4.280214924962643, "Platelet count increased ": 2.3382265826720823, "Polyp ": 2.6332618598522437, "Poor venous access ": 35.361104321313995, "Pouchitis ": 112.82113200213136, "Pre-eclampsia ": 2.262724999034128, "Pregnancy ": 49.55700468164199, "Proctalgia ": 8.529521921051762, "Proctitis ": 10.372175913626387, "Product administered to patient of inappropriate age ": 6.087613074228484, "Product dispensing error ": 2.6906942033592443, "Progressive multifocal leukoencephalopathy ": 4.6548154297163205, "Pulmonary toxicity ": 3.495428154083084, "Pyoderma gangrenosum ": 34.65867043786974, "Rectal abscess ": 16.549424687384747, "Rectal haemorrhage ": 5.321300057264114, "Rectal tenesmus ": 11.869816682032242, "Sacroiliitis ": 7.678206294414727, "Sinus congestion ": 2.7544747357014248, "Sinusitis ": 2.9998766469928646, "Skin infection ": 3.63556538695333, "Skin 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5.084157943884844, "Ulcer ": 4.879298707354844, "Urinary tract infection ": 2.166459099896034, "Uveitis ": 3.566458333413661, "Weight fluctuation ": 3.0078092019056752}
\ No newline at end of file
+{"Acute kidney injury": 2.04810167906518, "Alanine aminotransferase increased": 4.843629254406811, "Anxiety": 2.652666560137375, "Aspartate aminotransferase increased": 7.772110674524519, "Blood lactic acid increased": 134.77730553200527, "Death neonatal": 478.73827759828566, "Depression suicidal": 188.32462309535268, "Depressive symptom": 112.08186894398936, "Diplopia": 28.971876298800037, "Drug interaction": 2.1382454299435274, "Dysphagia": 9.334210902213693, "Eyelid ptosis": 108.78052370969765, "Foetal exposure during pregnancy": 7.100088648845284, "Haemorrhage": 5.8560969226171045, "Hepatic steatosis": 24.90715761283308, "Lipodystrophy acquired": 155.41778268445293, "Mitochondrial toxicity": 579.3875928474247, "Ophthalmoplegia": 288.0299812836236, "Paranoia": 49.72140767682633, "Product use in unapproved indication": 4.010025275051348, "Psychiatric decompensation": 296.7536430572005, "Psychomotor skills impaired": 135.3868717632304, "Psychotic disorder": 21.41372563484233, "Small for dates baby": 210.3907542436804, "Suicidal ideation": 7.090756800520585, "Tearfulness": 126.96567792080737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/41.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/41.json
index 37da0ce9ef4..c9d30f94792 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/41.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/41.json
@@ -1 +1 @@
-{"Chest pain ": 2.0644040767882013, "Hypertension ": 2.7938050323032027, "Migraine ": 6.846093138431921, "Paraesthesia ": 2.8224126900494286, "Tinnitus ": 5.60158434147851}
\ No newline at end of file
+{"Abdominal distension": 3.292101392059712, "Abdominal pain upper": 2.793036605226993, "Accidental exposure to product": 16.4360003560904, "Adverse reaction": 3.875114857249074, "Alopecia": 5.462129346050119, "Anti-cyclic citrullinated peptide antibody positive": 2.081341523009021, "Antinuclear antibody positive": 3.177340796473604, "Anuria": 14.202390116400744, "Aphasia": 2.923746329248005, "Arteriospasm coronary": 5.793285441238239, "Aura": 23.186656805414824, "Autoimmune thyroiditis": 2.424039290225444, "Back injury": 7.09043744963268, "Blepharospasm": 42.20613433301681, "Blood pressure measurement": 9.191573145381064, "Bowel movement irregularity": 3.2432268724035267, "Brain fog": 3.268385299087306, "Brain injury": 2.139986712000542, "Breast cancer stage III": 7.79164675246818, "Bursitis": 3.139894883279283, "C-reactive protein abnormal": 3.5456178278884525, "Cerebellar infarction": 3.178075505109658, "Cerebrospinal fluid leakage": 4.0286693249609575, "Cervicogenic headache": 71.70047280177272, "Cluster headache": 4.14003751531551, "Coeliac disease": 4.915214421095718, "Colitis ischaemic": 3.1063170347226383, "Colour blindness": 9.897092476525824, "Communication disorder": 9.291579852347326, "Concussion": 22.56975883311453, "Constipation": 15.589170233301614, "Contraindicated product administered": 2.795154230663162, "Coronavirus infection": 3.705681323963725, "Craniocerebral injury": 5.949531211454541, "Depression suicidal": 2.5189226955645347, "Device defective": 8.769783502184014, "Device delivery system issue": 4.530449728304679, "Device difficult to use": 207.11479710356355, "Device issue": 15.218411781893533, "Device leakage": 5.256034030510369, "Device malfunction": 4.726816190446971, "Device use error": 11.107103303147468, "Device use issue": 2.616640156045007, "Discomfort": 2.3317698309543617, "Disturbance in attention": 2.7433870361872024, "Drug dose omission by device": 77.35046358687033, "Drug effect less than expected": 3.6687031550867, "Drug ineffective": 2.3145696173374173, "Drug ineffective for unapproved indication": 11.235344633984166, "Drug intolerance": 7.435204947047585, "Dyschezia": 7.026971793146089, "Dyspepsia": 4.382542914875407, "Epilepsy": 6.548009661339111, "Extrapyramidal disorder": 9.768929181940658, "Faecaloma": 6.8489040889852495, "Faeces hard": 9.384499500005244, "Fear of injection": 6.181297852908173, "Fixed eruption": 3.779792294606543, "Flatulence": 2.208848699579594, "Flushing": 2.2407269747283283, "Galactorrhoea": 3.777469495971169, "Gastrointestinal infection": 2.094159217608264, "Gastrointestinal motility disorder": 7.849754223527122, "Gastrointestinal obstruction": 5.593351118093032, "Gastrointestinal sounds abnormal": 2.1278386228190107, "Gastrooesophageal reflux disease": 7.420863419813222, "Gingival disorder": 2.5220558977492886, "Heart rate abnormal": 2.8710208127939176, "Hostility": 32.03647695039577, "Hyperaesthesia teeth": 5.924323928203078, "Hypoaesthesia": 2.858227048889497, "Ileus": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/410.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/410.json
index a5bef21f684..c6fee5a5193 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/410.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/410.json
@@ -1 +1 @@
-{"Acute kidney injury ": 9.34802797271922, "Ascites ": 22.175002988121147, "Cardiac failure congestive ": 11.048272480415577, "Cardiomegaly ": 63.15613650567877, "Coronavirus infection ": 170.60553019527586, "Cough ": 2.138413298817364, "Drug interaction ": 5.816056793342344, "Drug level increased ": 98.44054676239128, "Dysphagia ": 8.96625979299257, "Haemoptysis ": 26.029058926580912, "Hypoglycaemia ": 4.931146788071819, "Immunosuppressant drug level increased ": 292.806821929976, "Inflammatory marker increased ": 179.42922398324947, "Labelled drug-drug interaction medication error ": 48.53508073081731, "Leukopenia ": 8.228827180716044, "Lower respiratory tract infection ": 19.765855286211934, "Lung consolidation ": 334.1482293927682, "Multimorbidity ": 960.2672617602084, "Myocardial ischaemia ": 67.86487204535443, "Oesophageal carcinoma ": 73.47984765264044, "Oesophageal perforation ": 1472.667815408806, "Off label use ": 3.501873125417027, "Pleural effusion ": 13.451571400694606, "Pneumonia ": 4.257978971336005, "Productive cough ": 20.920691495028183}
\ No newline at end of file
+{"Abdominal mass": 37.56341374531959, "Abdominal pain lower": 2.551243122979008, "Abdominal tenderness": 13.60593704558574, "Abdominal wall haematoma": 135.3112663266006, "Abdominal wall haemorrhage": 72.07732639141402, "Abortion": 7.398702397480677, "Abortion induced": 2.8455308581124723, "Abortion spontaneous": 2.1357151244559334, "Activated partial thromboplastin time prolonged": 15.25670284825008, "Acute generalised exanthematous pustulosis": 2.6237301834043785, "Acute hepatic failure": 2.5794787687430416, "Adrenal haemorrhage": 77.93836415905481, "Adrenal insufficiency": 2.243327091974564, "Anaemia": 2.444212782774576, "Aphasia": 2.3682076340175824, "Arterial haemorrhage": 38.33578699701604, "Blood loss anaemia": 6.090085565559107, "Brain herniation": 12.233605705415815, "Bullous haemorrhagic dermatosis": 162.20945636538409, "Caesarean section": 5.477125133142721, "Cerebral haematoma": 4.799247515370972, "Cerebral haemorrhage": 4.567303939783487, "Cerebral palsy": 25.110916280365636, "Cerebral venous thrombosis": 10.756780245405244, "Coagulation time prolonged": 28.389420293129294, "Coagulopathy": 13.738335032578778, "Compartment syndrome": 11.11984276046891, "Conjunctival haemorrhage": 4.899984886437539, "Cyanosis": 3.4746642989756, "Deep vein thrombosis": 5.706357594558674, "Dermatitis bullous": 9.50495150725252, "Diplegia": 6.879901814669852, "Drug-induced liver injury": 3.89117800935722, "Ecchymosis": 17.786160944173336, "Embolism": 7.126602790547773, "Embolism venous": 21.319653710963607, "Eosinophilia": 2.7695082547512886, "Epistaxis": 2.940861642340829, "Exposure during pregnancy": 13.156672238822791, "Exposure via breast milk": 9.155134733725795, "Extradural haematoma": 44.09704635554694, "Fibrin D dimer increased": 3.773735409118184, "Flank pain": 7.221311966094597, "Foetal death": 2.357001440023308, "Foetal exposure during pregnancy": 7.047913227351884, "Foetal growth restriction": 16.370230812643833, "Foetal heart rate abnormal": 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17.467115948530914, "Lower gastrointestinal haemorrhage": 13.996668065213663, "Maternal exposure during pregnancy": 4.164884810377942, "Melaena": 10.117487672013686, "Mixed liver injury": 11.647692276318914, "Mouth haemorrhage": 4.823493371573161, "Muscle haemorrhage": 17.843137279145306, "Necrosis": 4.677717287981768, "Needle issue": 3.113041600528252, "Nonreassuring foetal heart rate pattern": 290.96163174710216, "Occult blood positive": 18.83725540298517, "Oliguria": 4.933717572946102, "Paraplegia": 6.77966518748818, "Pelvic haematoma": 83.52936313648688, "Peripheral artery occlusion": 14.153750710791185, "Petechiae": 4.770014998758479, "Platelet count decreased": 6.913279144819396, "Post procedural haemorrhage": 9.70087128249471, "Posterior reversible encephalopathy syndrome": 3.1577240770324004, "Pre-eclampsia": 5.849637320878053, "Premature baby": 10.36649488442397, "Premature delivery": 6.690299099287812, "Premature labour": 6.233900652516304, "Procedural haemorrhage": 19.80189911359619, "Product prescribing issue": 5.360744623602257, "Prosthetic cardiac valve thrombosis": 299.41449900669267, "Prothrombin time prolonged": 10.546092911506326, "Pulmonary alveolar haemorrhage": 5.426935522074787, "Pulmonary embolism": 4.807079600792297, "Pulmonary haemorrhage": 5.888996357594936, "Purpura": 4.226771395374707, "Rash maculo-papular": 3.0281640612641554, "Rectal haemorrhage": 2.61097523996635, "Respiratory tract haemorrhage": 26.94783589277099, "Retroperitoneal haematoma": 107.98889786794795, "Retroperitoneal haemorrhage": 34.67923751944798, "Sensory loss": 2.4503240959509256, "Shock": 2.361211600935861, "Shock haemorrhagic": 23.622228929756737, "Sinus tachycardia": 3.4515770174706604, "Skin haemorrhage": 3.414989228674249, "Skin lesion": 2.6459952334587684, "Skin necrosis": 17.22136373769157, "Spinal epidural haematoma": 23.763461234837607, "Spinal epidural haemorrhage": 315.6799896660098, "Spontaneous haematoma": 8.298612168030408, "Subarachnoid haemorrhage": 3.860770312780645, "Subcutaneous haematoma": 15.1129362986102, "Subdural haematoma": 10.964894370530423, "Subdural haemorrhage": 12.60263181381288, "Tachypnoea": 3.765974249796874, "Talipes": 6.5458191915383015, "Tenderness": 2.290697421537317, "Thrombocytopenia": 4.58272727211944, "Thrombocytosis": 7.776974941528864, "Thrombosis": 3.0363057377211398, "Toxic epidermal necrolysis": 4.010032450121238, "Transaminases increased": 3.3015565480982723, "Type I hypersensitivity": 4.014915444221647, "Type IV hypersensitivity reaction": 11.178845643456992, "Upper gastrointestinal haemorrhage": 33.33119908280067, "Vaginal haemorrhage": 2.631411277773489, "Venous thrombosis": 6.833692388099344}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/411.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/411.json
index 81860d884ec..50fe0814030 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/411.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/411.json
@@ -1 +1 @@
-{"Acute myocardial infarction ": 2.11438949342669, "Amnesia ": 2.617336120980133, "Asthenia ": 2.531134296221345, "Bone pain ": 2.212184549356868, "Cardiac failure congestive ": 3.216598003308982, "Cognitive disorder ": 3.4751226011348493, "Constipation ": 2.8312609803086417, "Dehydration ": 2.584430308430509, "Drug interaction ": 4.238820824172262, "Erectile dysfunction ": 2.9694318195545573, "Faeces discoloured ": 4.086715239920283, "Fall ": 3.4681410299230726, "Gastrointestinal disorder ": 2.8013964642198563, "Gynaecomastia ": 8.348679304373578, "Haematuria ": 4.770931430403489, "Hot flush ": 12.87472113055851, "Malignant neoplasm progression ": 18.53751142033012, "Metastases to bone ": 21.176231017645318, "Metastases to spine ": 29.12586942559325, "Muscular weakness ": 2.015200400007508, "Pelvic pain ": 7.067882601254196, "Pollakiuria ": 3.5114183829130763, "Presyncope ": 2.195981414943367, "Prostate cancer ": 22.22920148214569, "Prostate cancer metastatic ": 102.2266905141083, "Prostatic specific antigen abnormal ": 192.27628273134397, "Prostatic specific antigen increased ": 217.35708087756328, "Restless legs syndrome ": 4.474860887646192, "Spinal compression fracture ": 11.137412704764388, "Underdose ": 6.262036910490101}
\ No newline at end of file
+{"Agitation": 3.0136677209233658, "Akinesia": 90.16038367664906, "Balance disorder": 4.513355337336894, "Behaviour disorder": 7.937667586832355, "Blood creatine phosphokinase increased": 4.588567024552758, "Bradykinesia": 56.495550805304994, "Chromaturia": 10.166329997854277, "Cognitive disorder": 5.504113140833774, "Colitis microscopic": 39.93642886008693, "Compulsive shopping": 140.37564444815737, "Constipation": 2.369206381252729, "Delirium": 2.3457006208151205, "Delusion": 32.72418609728828, "Dementia": 5.7229377599229245, "Depressed level of consciousness": 2.157269882727704, "Dopamine dysregulation syndrome": 672.2742716305228, "Drug abuse": 2.378851309861442, "Drug withdrawal syndrome": 4.927621321142853, "Dyskinesia": 63.78020925244957, "Dysphagia": 6.151914750372951, "Dysphonia": 2.1097123571783083, "Dystonia": 30.165469395079832, "Eating disorder": 7.421471110924092, "Fall": 2.7130066140295583, "Gait disturbance": 5.715369329060968, "Gambling disorder": 151.69592192483438, "General physical health deterioration": 2.4877322067064656, "Hallucination": 8.190409346291263, "Hallucination, visual": 30.772711995753465, "Hypersexuality": 165.4767100254095, "Hyperthermia": 7.379196534772826, "Hypokinesia": 12.360679957870936, "Hypomania": 18.694912954293475, "Hyponatraemia": 3.0186994814974075, "Impulse-control disorder": 92.71688525003526, "Impulsive behaviour": 51.4465266678604, "Incorrect dose administered": 2.009071232631149, "Irritability": 4.337784025041486, "Loss of personal independence in daily activities": 2.369763036930724, "Motor dysfunction": 29.35575909122322, "Movement disorder": 3.3393979533287625, "Muscle rigidity": 29.85303263033005, "Musculoskeletal stiffness": 3.854784034248912, "Mydriasis": 10.946730025066095, "Neuroleptic malignant syndrome": 19.767517285193183, "Nightmare": 3.683581612399953, "On and off phenomenon": 624.7224564583022, "Oromandibular dystonia": 258.7186522340258, "Orthostatic hypotension": 8.656847917878409, "Parkinson's disease": 89.26674060586625, "Parkinsonian gait": 195.87889138105592, "Parkinsonism": 25.524049144938555, "Persecutory delusion": 28.811704935331065, "Pollakiuria": 3.1450774877689414, "Psychomotor hyperactivity": 8.648030355705465, "Quality of life decreased": 10.613974978487114, "Respiratory failure": 2.269743185292916, "Resting tremor": 234.97208418261712, "Restlessness": 2.3831185347366843, "Rhabdomyolysis": 3.907979611635122, "Therapeutic response shortened": 174.86863291804755, "Treatment noncompliance": 3.288600916973963, "Tremor": 2.879741692276102, "Urinary incontinence": 4.874628567359238, "Urinary retention": 3.306935925816632, "Wrong technique in product usage process": 2.7074472992354206}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/412.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/412.json
index 097f8688a14..b1ef6d35b3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/412.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/412.json
@@ -1 +1 @@
-{"Angina pectoris ": 43.61989143589956, "Anxiety disorder ": 445.15862442643135, "Cellulitis ": 51.347739721160735, "Chest pain ": 7.247263622297539, "Chronic obstructive pulmonary disease ": 45.24116119535811, "Delirium ": 43.54642460147096, "Dementia Alzheimer's type ": 309.6623483634038, "Dermatitis atopic ": 403.043666715322, "Dyspepsia ": 25.38729919319676, "Haemorrhoids ": 104.38002836808998, "Hypothyroidism ": 38.0176560464381, "Iron deficiency anaemia ": 266.4204276526159, "Lung neoplasm malignant ": 75.57418514590347, "Metastatic neoplasm ": 756.3507176705792, "Pleural effusion ": 34.517328009414946, "Rash ": 3.432942976110694, "Schizophrenia ": 237.7034715968642, "Urinary tract infection ": 22.01120359325052, "Vitamin D deficiency ": 131.92898654040428}
\ No newline at end of file
+{"Abortion spontaneous": 3.2826850280997317, "Acute hepatic failure": 10.783547155231188, "Alanine aminotransferase increased": 9.492754356043614, "Aspartate aminotransferase increased": 4.788736362466789, "Blood HIV RNA decreased": 1119.2050576317483, "Blood bilirubin increased": 5.079653263444774, "Blood creatine phosphokinase increased": 5.632796378609466, "Blood creatinine increased": 7.8563184200077245, "Blood phosphorus decreased": 78.1716564135315, "Bone pain": 5.983482777487846, "Creatinine renal clearance decreased": 20.202244273293964, "Drug ineffective": 3.796279410230593, "Drug resistance": 109.3203281592032, "Fanconi syndrome acquired": 18.472107891819284, "Hepatic cancer": 8.954113847391804, "Hepatic cirrhosis": 17.91011149176656, "Hepatic enzyme increased": 2.0664092384616937, "Hepatic failure": 5.241794303683563, "Hepatic function abnormal": 3.891896903411976, "Hepatitis B": 113.90205205799128, "Hepatitis B DNA increased": 398.5147792574245, "Hepatitis B reactivation": 137.78668538384193, "Hepatocellular carcinoma": 9.974535134057517, "Hypophosphataemia": 83.70592078534567, "Jaundice": 5.625254493717801, "Lactic acidosis": 6.878527305442215, "Multiple-drug resistance": 19.48396269195553, "Osteomalacia": 48.0659823795009, "Pathogen resistance": 39.47302722295338, "Periorbital swelling": 21.459340586837158, "Platelet count decreased": 2.592392256979099, "Pregnancy": 18.56908384486345, "Protein urine present": 42.48409458101086, "Proteinuria": 6.678567825246477, "Rash maculo-papular": 2.4812485812290936, "Renal impairment": 5.902828834539954, "Rhabdomyolysis": 3.788695308583685, "Skin plaque": 14.51597262873656, "Swelling face": 2.182795241707037, "Therapeutic response decreased": 6.628839912534524, "Thrombocytopenia": 2.1674992764105627, "Transaminases increased": 3.8053048548216446, "Treatment noncompliance": 4.781881495143108, "Viral load increased": 102.31203578379056, "Viral mutation identified": 71.60971291362493, "Virologic failure": 57.82476222836497}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/413.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/413.json
index 3c96b4d169c..39e2fba2905 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/413.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/413.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.4904397223012094, "Ascites ": 13.8641180105857, "Blood bilirubin increased ": 4.663020411974359, "Circumstance or information capable of leading to medication error ": 12.398339783711886, "Death ": 2.4303649030213617, "Drug ineffective ": 9.002255395620162, "Encephalopathy ": 3.036195173689428, "Genotype drug resistance test positive ": 230.96761373882345, "Glomerular filtration rate decreased ": 5.476512084250556, "Hepatic cancer ": 7.215967324859996, "Hepatic cirrhosis ": 29.92627406492871, "Hepatic encephalopathy ": 25.13926692887764, "Hepatic failure ": 9.257989010077388, "Hepatitis B reactivation ": 9.815736919356604, "Hepatitis C ": 135.3773960995886, "Hepatitis C RNA positive ": 115.41334055001042, "Hepatitis C virus test positive ": 198.68358075290303, "Hepatocellular carcinoma ": 28.278685580557507, "Hepatorenal syndrome ": 24.785368289088403, "Incorrect product administration duration ": 4.173362157845683, "Intentional dose omission ": 41.02321788655625, "Intentional product use issue ": 3.967335430354284, "Liver disorder ": 2.227469251051033, "Liver transplant ": 57.531365047012585, "Oesophageal varices haemorrhage ": 32.49532311478416, "Product dose omission in error ": 7.067992508614373, "Product dose omission issue ": 3.3446125994245626, "Product use complaint ": 8.17758403890649, "Psychotic disorder ": 2.4212661204007366, "Spontaneous bacterial peritonitis ": 72.47677420815941, "Treatment failure ": 56.59400110519505, "Treatment noncompliance ": 12.993678037807232, "Varices oesophageal ": 27.045297843789857, "Virologic failure ": 11.769276594698924}
\ No newline at end of file
+{"Activated partial thromboplastin time prolonged": 2.617762956053923, "Acute kidney injury": 5.707418540045119, "Acute pulmonary oedema": 9.137260959862836, "Akinesia": 4.05736747784321, "Amyloidosis": 7.154680796279707, "Angioedema": 8.961703665004547, "Anuria": 4.921701033935137, "Aortic stenosis": 3.4958651742543574, "Aortic valve calcification": 17.68778272181648, "Aortic valve incompetence": 9.979374345995724, "Arrhythmic storm": 20.15894567754527, "Arterial haemorrhage": 5.577796016698047, "Asthma-chronic obstructive pulmonary disease overlap syndrome": 18.042183582852, "Atrial enlargement": 21.46485247400659, "Atrial fibrillation": 3.770533861723548, "Atrial flutter": 3.9373078428742767, "Atrioventricular block": 2.6746104957443557, "Atrioventricular block first degree": 3.1617787388566314, "Azotaemia": 3.160396016433929, "Bleeding time prolonged": 5.182148408632219, "Blood chloride decreased": 4.229118504721679, "Blood chloride increased": 16.278540927303148, "Blood creatine increased": 13.36585830485748, "Blood creatinine abnormal": 3.678835301739419, "Blood creatinine decreased": 2.5258460839354218, "Blood creatinine increased": 9.478057482141944, "Blood iron decreased": 3.172002068758169, "Blood phosphorus increased": 4.185427107854594, "Blood potassium abnormal": 4.0394517099962135, "Blood potassium decreased": 2.6413713536654835, "Blood potassium increased": 29.696279267929608, "Blood pressure abnormal": 5.915922562817076, "Blood pressure decreased": 9.14833724784057, "Blood pressure diastolic decreased": 5.326675410249894, "Blood pressure fluctuation": 2.816196528686957, "Blood pressure systolic abnormal": 5.338238989462096, "Blood pressure systolic decreased": 47.24903908371801, "Blood pressure systolic increased": 3.821362865648435, "Blood sodium decreased": 4.038709982335565, "Blood triglycerides increased": 3.1193379666092924, "Blood urea increased": 9.26840210392079, "Blood urea nitrogen/creatinine ratio increased": 14.509370548118682, "Blood uric acid increased": 5.993897309208055, "Body mass index decreased": 58.2699137992591, "Brain natriuretic peptide abnormal": 31.065263152780187, "Brain natriuretic peptide increased": 22.80125123847497, "Breath sounds abnormal": 3.007565562611109, "Bronchial hyperreactivity": 7.795532045927324, "Bundle branch block left": 11.71035244551503, "Cardiac disorder": 2.196983400708476, "Cardiac dysfunction": 23.83435988466822, "Cardiac failure": 19.27439194274535, "Cardiac failure acute": 13.252002112572542, "Cardiac failure chronic": 37.40315701387538, "Cardiac failure congestive": 3.1972436373840205, "Cardiac function test abnormal": 51.483650746269966, "Cardiac murmur": 2.148472368833928, "Cardiac output decreased": 9.904013835479198, "Cardiac ventricular disorder": 26.397360822912308, "Cardiac ventricular thrombosis": 2.868965788929204, "Cardiogenic shock": 8.206561567190434, "Cardiomegaly": 3.8053994364115713, "Cardiomyopathy": 7.454447152644716, "Cardiorenal syndrome": 48.39212622070965, "Cardiovascular insufficiency": 3.683105492181041, "Computerised tomogram heart abnormal": 83.59527123745303, "Concomitant disease aggravated": 4.149549186116058, "Congestive hepatopathy": 8.384737529573558, "Contraindicated product administered": 6.692959633049774, "Cough": 2.4542100177914543, "Craniocerebral injury": 4.222639285865616, "Creatinine renal clearance decreased": 3.23681990328769, "Creatinine renal clearance increased": 5.73173930702683, "Death": 2.4896024292829377, "Dehydration": 2.78746555149072, "Dementia": 2.07362891943684, "Device inappropriate shock delivery": 245.0806903727404, "Diastolic dysfunction": 14.840339271146098, "Dilatation atrial": 13.473400645138348, "Dilated cardiomyopathy": 14.265133013679788, "Dizziness postural": 4.6962221369103645, "Dyslipidaemia": 3.799857783534837, "Dyspnoea at rest": 6.922070749485373, "Dyspnoea exertional": 2.944505933026446, "Dyspnoea paroxysmal nocturnal": 19.07967881430109, "Ejection fraction": 6.896740868282619, "Ejection fraction abnormal": 35.7475720262455, "Ejection fraction decreased": 32.600404703756325, "Electrocardiogram ST segment elevation": 3.4663151846904494, "Electrocardiogram T wave inversion": 6.10130576216825, "Electrocardiogram abnormal": 2.6627722430024354, "Erysipelas": 2.421818471548661, "Essential hypertension": 3.5948513258117534, "Exercise tolerance decreased": 3.177245322363361, "Faeces hard": 2.565934927019133, "Feeling abnormal": 2.0973476118755903, "Fluid intake reduced": 5.647244532364818, "Fluid retention": 4.289573985110072, "General physical condition abnormal": 4.123896193324312, "General physical health deterioration": 2.3548803371662985, "Glomerular filtration rate abnormal": 4.997079519827066, "Glomerular filtration rate decreased": 35.55669847920228, "Glomerular filtration rate increased": 9.25722964247403, "Gout": 4.925266766803385, "Gynaecomastia": 4.515124351117639, "Haematocrit decreased": 3.153285875838852, "Haemoglobin increased": 3.014614820253325, "Head injury": 2.1249779247579745, "Heart failure with preserved ejection fraction": 30.516256251498195, "Heart failure with reduced ejection fraction": 56.69108818540332, "Heart rate abnormal": 4.122690429358669, "Heart rate decreased": 4.860297003144631, "Heart rate irregular": 3.0873467514235187, "High density lipoprotein decreased": 13.061225053515928, "Hyperkalaemia": 19.19360798282992, "Hypertensive heart disease": 12.308155954952712, "Hypervolaemia": 9.188865675520768, "Hypochromasia": 110.26949182621678, "Hypokinesia": 3.0643111319493146, "Hypotension": 15.41447197991346, "Hypovolaemia": 6.750063890942708, "Hypovolaemic shock": 2.0526053614482795, "Implantable defibrillator insertion": 7.521236884866854, "Inappropriate schedule of product administration": 3.678077890179571, "Incorrect dosage administered": 2.2431440202247144, "Incorrect dose administered": 2.03495480429601, "Infarction": 2.5990211841000885, "International normalised ratio abnormal": 2.113247653499666, "International normalised ratio fluctuation": 5.142195874885386, "Ischaemic cardiomyopathy": 19.16912200475098, "Ischaemic hepatitis": 10.09415479386784, "Left atrial dilatation": 13.847323651152758, "Left atrial enlargement": 30.113201636170395, "Left ventricular dilatation": 26.345040155626634, "Left ventricular dysfunction": 16.764707657584573, "Left ventricular enlargement": 67.98384027123443, "Left ventricular failure": 3.863290671981001, "Left ventricular hypertrophy": 6.928718050347364, "Lip swelling": 4.290624792527113, "Lymphocyte count decreased": 2.484464169302409, "Lymphocyte percentage decreased": 6.499894652432314, "Mean platelet volume increased": 43.03522717998387, "Meniscus injury": 2.832516971038215, "Mitral valve incompetence": 12.87866634901938, "Mitral valve thickening": 147.5725274569521, "Myocardial infarction": 2.363289624422017, "Myocardial ischaemia": 2.1172057876936594, "N-terminal prohormone brain natriuretic peptide increased": 100.90825695767376, "Nasal pruritus": 5.141645180688413, "Near death experience": 15.058884646759312, "Neutrophil count increased": 3.0112822457471373, "Nipple pain": 3.6366776258785545, "Nocturia": 2.5170997443812606, "Normochromic anaemia": 13.617549779275077, "Oedema": 3.962296584273642, "Oedema peripheral": 3.797591209794797, "Oliguria": 2.3769549331181525, "Orthopnoea": 22.99954149103805, "Orthostatic hypotension": 6.105902987583311, "Pollakiuria": 2.604135152429276, "Polyuria": 5.092098920893879, "Prerenal failure": 4.001117735199706, "Prescribed underdose": 12.828336572077127, "Product monitoring error": 11.71672629759177, "Product prescribing error": 7.364862618951516, "Product use in unapproved indication": 2.2603264592795003, "Pruritus": 2.2048998024556856, "Pulmonary congestion": 4.078697337071549, "Pulmonary function test abnormal": 5.357829792949751, "Pulmonary hypertension": 3.667162414004477, "Pulmonary oedema": 3.815012638596467, "Radius fracture": 4.409715182969413, "Rales": 5.769772770862655, "Red cell distribution width increased": 11.609380249174064, "Renal disorder": 3.146332467735674, "Renal failure": 4.468865087174, "Renal function test abnormal": 5.806817070336124, "Renal impairment": 9.955752740250624, "Right atrial enlargement": 21.581307794944863, "Right ventricular dysfunction": 9.651148461207525, "SARS-CoV-2 test": 27.96750828522805, "Scan myocardial perfusion": 363.8191432832047, "Sinus bradycardia": 3.0761555731222883, "Sudden cardiac death": 9.954921975853894, "Sudden death": 5.656351127387332, "Swelling face": 2.654290262407296, "Swollen tongue": 3.5034004295996666, "Systolic dysfunction": 11.076860304589946, "Throat clearing": 17.351382960204543, "Traumatic intracranial haemorrhage": 8.014231865138628, "Tricuspid valve incompetence": 11.18877834642918, "Underdose": 7.808026541715906, "Upper respiratory tract inflammation": 7.829788801541455, "Urine output decreased": 4.677211542612704, "Urine output increased": 4.504381016562586, "Vasoplegia syndrome": 8.429467771479342, "Vein disorder": 2.562815872808366, "Venous pressure jugular decreased": 162.2718563149147, "Venous pressure jugular increased": 35.229315701683525, "Ventricular arrhythmia": 4.719421345014501, "Ventricular extrasystoles": 5.12228443675819, "Ventricular fibrillation": 3.982400600795079, "Ventricular hyperkinesia": 86.58848158698123, "Ventricular hypokinesia": 5.468852504959744, "Ventricular tachycardia": 8.380094961380163, "Viral diarrhoea": 57.868689420113824, "Weight fluctuation": 8.420773088242267, "Weight increased": 2.5407256681916643, "Wrong technique in product usage process": 13.034081218463443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/414.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/414.json
index 3fa369f3083..d6b16b1f054 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/414.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/414.json
@@ -1 +1 @@
-{"C-reactive protein increased ": 11.71254140234428, "COVID-19 ": 3.060116380183333, "COVID-19 pneumonia ": 49.54761825988718, "Cytokine release syndrome ": 379.7417768100353, "Decreased appetite ": 2.364031734593481, "Diffuse large B-cell lymphoma ": 159.19376077073815, "Disease progression ": 3.6644220636030767, "Febrile neutropenia ": 16.946923541004338, "Hypotension ": 3.231437207368858, "Immune effector cell-associated neurotoxicity syndrome ": 150.5355155179341, "Malignant neoplasm progression ": 3.0098643443827173, "Neutropenia ": 3.7494234332082654, "Neutrophil count decreased ": 10.345268278557809, "Pneumonia ": 8.065252755109903, "Pyrexia ": 2.1740585214328405, "Sepsis ": 4.944034668691656}
\ No newline at end of file
+{"Abdominal abscess": 11.879607178068024, "Abdominal distension": 2.6581197604413376, "Abdominal pain": 2.8330309400056337, "Abdominal pain lower": 2.620234536739679, "Abnormal faeces": 5.5651680839521935, "Abortion spontaneous": 3.2573842129482307, "Abscess": 9.924780317733337, "Abscess intestinal": 34.765149356711426, "Acne": 4.772925638971505, "Adenocarcinoma of colon": 13.484644593233384, "Adverse drug reaction": 2.818736795473397, "Anal abscess": 46.85057827260443, "Anal fissure": 15.450398230256704, "Anal fistula": 37.91216443536936, "Anal incontinence": 4.067658519168047, "Anal inflammation": 22.92506793389697, "Anal ulcer": 16.05574363502386, "Ankylosing spondylitis": 4.698751837196362, "Anorectal discomfort": 7.909111105889431, "Anorectal disorder": 12.496014678411148, "Appendicitis": 4.492587238057249, "Arthritis": 2.1640076405611333, "Autoimmune haemolytic anaemia": 2.623675306513313, "B-cell lymphoma": 4.316292399039281, "Bacillus infection": 102.83624474216896, "Bacterial vulvovaginitis": 220.60821015736235, "Blood iron decreased": 4.056193899914514, "Bowel movement irregularity": 6.069815014535119, "Breast cancer female": 2.071656875214885, "Breast cancer stage II": 3.234599580039717, "C-reactive protein increased": 2.0432495732709643, "Calcium deficiency": 20.181014780779343, "Cataract": 2.112047014879461, "Cellulitis": 2.259949468186108, "Central obesity": 51.14236294057951, "Cholangitis": 2.339517191169831, "Cholangitis sclerosing": 31.77950780048792, "Cholecystectomy": 2.7426735023365176, "Clostridium difficile infection": 12.695095164684687, "Colectomy": 54.74219325776433, "Colitis": 6.304240024231298, "Colitis ulcerative": 71.64935860009636, "Colon cancer": 3.036357706458535, "Colonic abscess": 25.90566922264777, "Condition aggravated": 2.03025357240017, "Coronavirus infection": 2.3506711652849472, "Crohn's disease": 43.589864520701134, "Cushingoid": 16.900483375084338, "Cutaneous vasculitis": 3.0065813612344474, "Cytomegalovirus colitis": 8.797047455908919, "Cytomegalovirus enterocolitis": 17.596118845037612, "Cytomegalovirus infection": 4.109274553949633, "Defaecation urgency": 38.79022257673147, "Device leakage": 3.0827337890570297, "Diarrhoea haemorrhagic": 17.842203377836753, "Dislocation of vertebra": 2.889439126500664, "Drug effect less than expected": 18.341086226131743, "Drug hypersensitivity": 2.293015245031648, "Drug ineffective": 2.555018945450072, "Drug level below therapeutic": 4.902507676548333, "Drug level decreased": 17.019534487158037, "Drug specific antibody present": 47.250327320296016, "Dyschezia": 12.189379562210648, "Ear infection": 3.067481058346367, "Eastern Cooperative Oncology Group performance status worsened": 9.535097593594932, "Enteritis": 6.376681579869368, "Enteritis infectious": 9.82426809384146, "Enterocutaneous fistula": 26.68968019775779, "Eosinophilic pneumonia": 3.9566100429229296, "Epstein-Barr virus infection": 3.100352511224516, "Erythema nodosum": 11.642407641011555, "Escherichia infection": 9.091877979857244, "Faecal calprotectin abnormal": 86.98014732286052, "Faecal calprotectin increased": 76.93288311293163, "Faeces hard": 5.763647701938968, "Faeces soft": 11.179882676348289, "Female genital tract fistula": 2.0973478190704777, "Fistula": 21.32662641913339, "Flatulence": 4.681531096238503, "Frequent bowel movements": 28.073236052895368, "Furuncle": 12.666403558861816, "Gastroenteritis eosinophilic": 30.824288151535647, "Gastroenteritis viral": 2.311352410244072, "Gastrointestinal infection": 4.299004256089062, "Gastrointestinal inflammation": 19.361955417513503, "Gastrointestinal mucosa hyperaemia": 46.55142795915202, "Gastrointestinal pain": 2.31231258260322, "Gastrointestinal ulcer": 17.22851839635191, "Gastrointestinal wall thickening": 24.160542691650825, "General symptom": 7.0341645449440815, "Granuloma": 3.6075009964293816, "Haematochezia": 11.78514504555582, "Haemorrhoids": 3.0361757505943547, "Hidradenitis": 7.238115992178653, "Histoplasmosis": 21.14950598665603, "Hunger": 2.0643497122275343, "Ileal stenosis": 79.89288888786486, "Ileostomy": 14.746322769760216, "Immune thrombocytopenia": 2.520634750720948, "Immunosuppression": 2.516292671338029, "Impaired quality of life": 4.275595788849079, "Inflammatory bowel disease": 22.875901005054715, "Infusion related reaction": 2.1929421162686924, "Infusion site extravasation": 4.642307028150763, "Infusion site pain": 3.284082859066214, "Injection site discharge": 98.48105345329606, "Injection site extravasation": 5.787810905398385, "Injection site hypersensitivity": 8.125794973264224, "Injection site oedema": 2.946697413264264, "Injection site pruritus": 2.282432487085737, "Injection site rash": 2.7707804589218825, "Injection site reaction": 2.754733356731633, "Injection site urticaria": 5.091613124159944, "Intestinal fistula": 31.491377562337632, "Intestinal obstruction": 9.282704403497831, "Intestinal perforation": 2.190646988903055, "Intestinal resection": 33.786477235490736, "Intestinal stenosis": 59.953559812816586, "Intestinal ulcer": 16.29536186081414, "Iron deficiency": 7.683403382631144, "JC polyomavirus test positive": 37.39964027356265, "Large intestinal stenosis": 38.96286973590514, "Large intestinal ulcer": 11.656347346359956, "Large intestine perforation": 3.027198750737247, "Large intestine polyp": 4.296989141754599, "Liver abscess": 4.677537568749773, "Loss of therapeutic response": 70.22007912047457, "Lower respiratory tract infection": 2.836568719064037, "Lupus-like syndrome": 11.810202608305971, "Malnutrition": 3.180561977262026, "Maternal exposure during breast feeding": 2.113762683026138, "Mouth ulceration": 3.5550785548762205, "Mucous stools": 46.72307567025556, "Nasopharyngitis": 3.1117097512727536, "Nipple pain": 4.677537568749773, "Off label use": 4.0240788673844285, "Organising pneumonia": 3.441263722879807, "Overgrowth bacterial": 56.06992138782134, "Pharyngitis": 2.0146480372178823, "Pharyngitis streptococcal": 4.278141247368636, "Platelet count increased": 2.3370937176270234, "Polyp": 2.6319860867702136, "Poor venous access": 35.3439712730702, "Pouchitis": 112.7664708450598, "Pre-eclampsia": 2.261628754270127, "Pregnancy": 49.53298732833145, "Proctalgia": 8.525389287369626, "Proctitis": 10.367150263375128, "Product administered to patient of inappropriate age": 6.084663510162923, "Product dispensing error": 2.68939055319414, "Progressive multifocal leukoencephalopathy": 4.65256022130237, "Pulmonary toxicity": 3.493734622774224, "Pyoderma gangrenosum": 34.64187758209252, "Rectal abscess": 16.54140683664536, "Rectal haemorrhage": 5.318721343461029, "Rectal tenesmus": 11.864065952640306, "Sacroiliitis": 7.674486344186157, "Sinus congestion": 2.7531402369466464, "Sinusitis": 2.9984230112493626, "Skin infection": 3.633803981839222, "Skin reaction": 2.029156262539256, "Small intestinal obstruction": 6.421678803115421, "Spondylitis": 11.333310285782302, "Squamous cell carcinoma of skin": 2.6684145307840272, "Stenosis": 8.545992426778799, "Steroid dependence": 34.89743381183963, "Stillbirth": 2.7755263595335102, "Stress": 3.0568258787057005, "Subcutaneous abscess": 3.281196010387264, "Surgery": 4.8135869760500976, "Therapeutic product effect delayed": 7.088025723293512, "Therapeutic product effect incomplete": 2.183534617814784, "Therapeutic reaction time decreased": 2992.497252053788, "Therapeutic response shortened": 2.567559095567556, "Therapy non-responder": 8.903220657451326, "Therapy partial responder": 3.8479512487290575, "Tonsillitis": 3.722835766120965, "Tooth abscess": 2.258989895423206, "Tooth infection": 3.041875013652499, "Treatment failure": 4.194842276239306, "Treatment noncompliance": 5.679724196101415, "Tuberculosis": 2.8264800688785736, "Tubulointerstitial nephritis": 5.081694462987753, "Ulcer": 4.8769346220619605, "Urinary tract infection": 2.165409263381896, "Uveitis": 3.564730332225373, "Weight fluctuation": 3.006351972693434}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/415.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/415.json
index e628e695625..101da629483 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/415.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/415.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 15.059179866566067, "Aggression ": 15.259360716774268, "Agitation ": 4.205031584680556, "Alanine aminotransferase increased ": 5.166685887179913, "Aspartate aminotransferase increased ": 4.207544208629049, "Condition aggravated ": 3.055847864664908, "Decreased appetite ": 4.6146235743076485, "Diarrhoea ": 2.476506055044936, "Drug ineffective ": 2.047575390866384, "Drug interaction ": 5.851466728703322, "Epilepsy ": 11.781796004675943, "Gait disturbance ": 3.542660249876295, "Generalised tonic-clonic seizure ": 9.221365612661124, "Hepatic enzyme increased ": 4.403209668746546, "Irritability ": 9.332812909565618, "Off label use ": 2.028932056195232, "Overdose ": 5.686020081046888, "Product use in unapproved indication ": 3.8852661600978617, "Sedation ": 45.62015425726177, "Seizure ": 13.843303593399268, "Somnolence ": 8.75558967888187, "Therapeutic response unexpected ": 31.182571112175136, "Weight decreased ": 2.4581375408619914}
\ No newline at end of file
+{"Acute kidney injury": 9.34802797271922, "Ascites": 22.175002988121147, "Cardiac failure congestive": 11.047437022675611, "Cardiomegaly": 63.15613650567877, "Coronavirus infection": 170.60553019527586, "Cough": 2.1383934665816864, "Drug interaction": 5.816056793342344, "Drug level increased": 98.44054676239128, "Dysphagia": 8.96625979299257, "Haemoptysis": 26.029058926580912, "Hypoglycaemia": 4.930980351111323, "Immunosuppressant drug level increased": 292.806821929976, "Inflammatory marker increased": 179.42922398324947, "Labelled drug-drug interaction medication error": 48.53508073081731, "Leukopenia": 8.227790029918001, "Lower respiratory tract infection": 19.765855286211934, "Lung consolidation": 334.1482293927682, "Multimorbidity": 960.2672617602084, "Myocardial ischaemia": 67.86487204535443, "Oesophageal carcinoma": 73.47984765264044, "Oesophageal perforation": 1472.667815408806, "Off label use": 3.5017352026266177, "Pleural effusion": 13.450332961655564, "Pneumonia": 4.257978971336005, "Productive cough": 20.920691495028183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/416.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/416.json
index af4febb92fd..323bc509c73 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/416.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/416.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.3277789678622307, "Haemoglobin decreased ": 5.601204371698806, "Hepatic function abnormal ": 8.258949751227288, "Myelosuppression ": 123.38111695133507, "Neutrophil count decreased ": 43.10991943446583, "Off label use ": 3.2390669510034806, "Platelet count decreased ": 11.678395770816712, "Vomiting ": 3.3432163675487208, "White blood cell count decreased ": 50.06382320888917}
\ No newline at end of file
+{"Acute myocardial infarction": 2.111585689205826, "Amnesia": 2.6138646826990604, "Asthenia": 2.5495220769282487, "Bone pain": 2.2092506061157544, "Cardiac failure congestive": 3.2120880413321307, "Cognitive disorder": 3.470513562310743, "Constipation": 2.8275041841893995, "Dehydration": 2.5808639731434733, "Drug interaction": 4.233193517725465, "Erectile dysfunction": 2.9654940665853253, "Faeces discoloured": 4.0812958620843895, "Fall": 3.463448701780629, "Gastrointestinal disorder": 2.7975921204602505, "Gynaecomastia": 8.337607562842555, "Haematuria": 4.764602616590835, "Hot flush": 12.857630583700436, "Malignant neoplasm progression": 18.5128738374094, "Metastases to bone": 21.148135323764144, "Metastases to spine": 29.087245830294464, "Muscular weakness": 2.0125270663613897, "Pelvic pain": 7.058510180524085, "Pollakiuria": 3.50676153575294, "Presyncope": 2.193068961348544, "Prostate cancer": 22.199702073126844, "Prostate cancer metastatic": 102.09108999847425, "Prostatic specific antigen abnormal": 192.02129775730407, "Prostatic specific antigen increased": 217.0682892284273, "Restless legs syndrome": 4.468926961792873, "Spinal compression fracture": 11.122643435363273, "Underdose": 6.25373141845061}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/417.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/417.json
index 4ffd9fec245..40129066116 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/417.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/417.json
@@ -1 +1 @@
-{"Abortion ": 13.029016481270984, "Abortion induced ": 5.778234555351153, "Abortion spontaneous ": 2.824132659772705, "Abulia ": 28.384495193864304, "Alanine aminotransferase increased ": 4.515731423604952, "Amylase increased ": 7.52748075588499, "Anaemia ": 3.917801383436789, "Anaemia macrocytic ": 20.41601545663509, "Ascites ": 2.423103024940346, "Aspartate aminotransferase increased ": 4.619391561027788, "Atrial septal defect ": 7.336026015714461, "Blood HIV RNA increased ": 28.836376872901727, "Blood alkaline phosphatase increased ": 5.688429452210458, "Blood bilirubin increased ": 3.3208884934792406, "Blood creatine phosphokinase increased ": 4.994035138708592, "Blood creatinine increased ": 2.6522426184794075, "Blood culture positive ": 26.825761801253947, "Blood lactate dehydrogenase increased ": 5.323866467033643, "Blood lactic acid increased ": 36.96344941393885, "Blood triglycerides increased ": 7.853861671449067, "Brain death ": 15.313579017993831, "Breast enlargement ": 10.050274068551545, "Caesarean section ": 15.167831135866484, "Candida infection ": 2.671800635708834, "Cardiac murmur ": 3.982613329617241, "Cardiomyopathy ": 4.148974458859302, "Central nervous system lymphoma ": 38.90920211271096, "Cerebral toxoplasmosis ": 90.456990882979, "Cholestasis ": 2.3943419227750757, "Coronary artery disease ": 2.7273975375667847, "Depressive symptom ": 7.813857619497842, "Developmental delay ": 8.52934270670302, "Diabetes mellitus ": 8.010185872004477, "Disorientation ": 2.6282082386729706, "Disseminated intravascular coagulation ": 2.0704977563861364, "Drug resistance ": 3.809719538367165, "Dyslipidaemia ": 4.8798026076846375, "Facial wasting ": 197.20698136397948, "Failure to thrive ": 14.384959634017967, "Foetal exposure during pregnancy ": 7.530997689333515, "Foetal growth restriction ": 5.410604103513777, "Gamma-glutamyltransferase increased ": 6.249540266558678, "Guillain-Barre syndrome ": 2.279550551440222, "Haemophagocytic lymphohistiocytosis ": 5.60846677252474, "Hepatic cirrhosis ": 10.081449847375742, "Hepatic failure ": 5.158185731886874, "Hepatic function abnormal ": 3.12602261018401, "Hepatic steatosis ": 12.599659604994558, "Hepatitis ": 4.135144464804229, "Hepatitis B ": 15.767705158215668, "Hepatitis C ": 2.395455472995975, "Hepatitis cholestatic ": 6.619742538631544, "Hepatitis fulminant ": 10.874454746272315, "Hepatomegaly ": 8.620628971074215, "Hepatosplenomegaly ": 14.536455110451652, "Herpes virus infection ": 6.384761337558008, "Hyperbilirubinaemia ": 8.815671634720543, "Hypercholesterolaemia ": 14.79790248279143, "Hyperlactacidaemia ": 45.66328965745541, "Hyperlipidaemia ": 2.963032159665238, "Hyperreflexia ": 12.526994702101018, "Hyperthyroidism ": 2.349410922065468, "Hypertonia ": 6.0388137392567, "Hypertriglyceridaemia ": 51.79666303790715, "Hypophagia ": 2.760550249175187, "Immune reconstitution inflammatory syndrome ": 60.00885722172054, "JC virus infection ": 38.38209824326554, "Jaundice ": 2.042905083610589, "Lactic acidosis ": 15.513690838318295, "Leukopenia ": 4.605438958206982, "Lipase increased ": 9.724482354172173, "Lipoatrophy ": 190.60670605547568, "Lipodystrophy acquired ": 91.77322139930904, "Live birth ": 6.587160846630346, "Locked-in syndrome ": 129.8796683858363, "Low birth weight baby ": 7.499620128094573, "Lung infiltration ": 5.115284128498868, "Lymphoma ": 3.4342327172845644, "Macrocytosis ": 33.722367037941495, "Metabolic acidosis ": 2.752790521771012, "Mycobacterium avium complex infection ": 22.917102689188237, "Myocardial infarction ": 2.395919733274142, "Nephrolithiasis ": 2.301547451766021, "Nervous system disorder ": 4.450318610071912, "Neuropathy peripheral ": 2.9641948363014445, "Neutropenia ": 3.829720291607889, "Oral candidiasis ": 4.697492849660551, "Osteonecrosis ": 2.667810004557924, "Pancreatitis ": 5.453320870769771, "Pancreatitis acute ": 2.743474523763604, "Pancytopenia ": 4.667102129145656, "Patent ductus arteriosus ": 9.991896921848657, "Pathogen resistance ": 7.643189522437596, "Placental disorder ": 34.128575768762055, "Pneumocystis jirovecii pneumonia ": 9.083205861262153, "Portal hypertension ": 18.97363116246328, "Pregnancy ": 25.296389568421983, "Premature baby ": 7.312124600425434, "Premature delivery ": 11.130256088603078, "Premature rupture of membranes ": 17.51643184253225, "Progressive multifocal leukoencephalopathy ": 17.022703380064378, "Pulmonary hypertension ": 3.183165601144518, "Renal impairment ": 3.2213529768719487, "Renal tubular necrosis ": 8.437768423092422, "Road traffic accident ": 3.20995362622218, "Shock ": 2.4972995614281515, "Skin ulcer ": 2.2922558938832016, "Speech disorder developmental ": 12.35470784800599, "Subdural haematoma ": 2.282145280074888, "Sudden death ": 3.73143393117829, "Tuberculosis ": 14.217524984773917, "Varices oesophageal ": 35.63120988309785, "Ventricular tachycardia ": 2.4952011923170843, "Virologic failure ": 7.575623127779882}
\ No newline at end of file
+{"Angina pectoris": 43.61989143589956, "Anxiety disorder": 445.15862442643135, "Cellulitis": 51.347739721160735, "Chest pain": 7.247263622297539, "Chronic obstructive pulmonary disease": 45.24116119535811, "Delirium": 43.54642460147096, "Dementia Alzheimer's type": 309.6623483634038, "Dermatitis atopic": 403.043666715322, "Dyspepsia": 25.38729919319676, "Haemorrhoids": 104.38002836808998, "Hypothyroidism": 38.0176560464381, "Iron deficiency anaemia": 266.32579582675174, "Lung neoplasm malignant": 75.57418514590347, "Metastatic neoplasm": 756.3507176705792, "Pleural effusion": 34.514150253070625, "Rash": 3.432895823612338, "Schizophrenia": 237.7034715968642, "Urinary tract infection": 22.01120359325052, "Vitamin D deficiency": 131.92898654040428}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/418.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/418.json
index 76931d5f25a..b63684e561f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/418.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/418.json
@@ -1 +1 @@
-{"Abdominal pain ": 4.483985858295148, "Anaemia ": 6.181664173220954, "Anti-erythropoietin antibody negative ": 675.2947513744114, "Anti-erythropoietin antibody positive ": 349.5703420902292, "Aplasia pure red cell ": 210.8803792217742, "Bone marrow failure ": 17.292079470352064, "Bone pain ": 2.433837319595624, "Deep vein thrombosis ": 2.58090204766743, "Device interaction ": 9632.533523763224, "Diarrhoea ": 2.699134427406748, "Drug ineffective ": 2.362400069518772, "Drug specific antibody absent ": 143.78375634679756, "Exposure during pregnancy ": 2.7412136027599825, "Foetal exposure during pregnancy ": 4.360072085638552, "Haematocrit decreased ": 9.229948820867802, "Haemoglobin decreased ": 11.75485243820902, "Hypersensitivity ": 6.2048405343566255, "Hypotension ": 5.980132697694561, "Live birth ": 21.275077080012537, "Low birth weight baby ": 13.5985602262372, "Maternal exposure during pregnancy ": 4.690423265148625, "Myelodysplastic syndrome ": 12.66255227373563, "Neutralising antibodies positive ": 361.4433936119351, "Platelet count decreased ": 12.326939414657756, "Premature baby ": 8.7230998826782, "Premature delivery ": 14.321792496065203, "Premature rupture of membranes ": 56.56878537110124, "Therapeutic response decreased ": 9.214228158083106, "Transfusion ": 24.32321647747281}
\ No newline at end of file
+{"Abortion spontaneous": 2.4904397223012094, "Ascites": 13.8641180105857, "Blood bilirubin increased": 4.663020411974359, "Circumstance or information capable of leading to medication error": 12.398339783711886, "Death": 2.4303649030213617, "Drug ineffective": 9.002188632035228, "Encephalopathy": 3.036195173689428, "Genotype drug resistance test positive": 230.96761373882345, "Glomerular filtration rate decreased": 5.476512084250556, "Hepatic cancer": 7.215967324859996, "Hepatic cirrhosis": 29.92627406492871, "Hepatic encephalopathy": 25.13926692887764, "Hepatic failure": 9.257989010077388, "Hepatitis B reactivation": 9.815736919356604, "Hepatitis C": 135.3773960995886, "Hepatitis C RNA positive": 115.41334055001042, "Hepatitis C virus test positive": 198.68358075290303, "Hepatocellular carcinoma": 28.278685580557507, "Hepatorenal syndrome": 24.785368289088403, "Incorrect product administration duration": 4.173362157845683, "Intentional dose omission": 41.02321788655625, "Intentional product use issue": 3.967335430354284, "Liver disorder": 2.227469251051033, "Liver transplant": 57.531365047012585, "Oesophageal varices haemorrhage": 32.49532311478416, "Product dose omission in error": 7.067992508614373, "Product dose omission issue": 3.3446125994245626, "Product use complaint": 8.17758403890649, "Psychotic disorder": 2.4212661204007366, "Spontaneous bacterial peritonitis": 72.47677420815941, "Treatment failure": 56.59400110519505, "Treatment noncompliance": 12.993678037807232, "Varices oesophageal": 27.045297843789857, "Virologic failure": 11.769276594698924}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/419.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/419.json
index 0f116c39733..2df07b20536 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/419.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/419.json
@@ -1 +1 @@
-{"Drug ineffective ": 5.43782934777401, "Drug ineffective for unapproved indication ": 107.71962629765838, "Factor VIII inhibition ": 284.07402197546674, "Haemorrhage ": 35.604339240848724}
\ No newline at end of file
+{"C-reactive protein increased": 11.71254140234428, "COVID-19": 3.0600996923232904, "COVID-19 pneumonia": 49.54761825988718, "Cytokine release syndrome": 379.7417768100353, "Decreased appetite": 2.3640088048843304, "Diffuse large B-cell lymphoma": 159.19376077073815, "Disease progression": 3.6644220636030767, "Febrile neutropenia": 16.946923541004338, "Hypotension": 3.231362503551526, "Immune effector cell-associated neurotoxicity syndrome": 150.5355155179341, "Malignant neoplasm progression": 3.0098643443827173, "Neutropenia": 3.7492622051119904, "Neutrophil count decreased": 10.345268278557809, "Pneumonia": 8.065252755109903, "Pyrexia": 2.1740120889876886, "Sepsis": 4.944034668691656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/42.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/42.json
index 0b1eb6d1982..234fd7d28fb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/42.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/42.json
@@ -1 +1 @@
-{"Drug interaction ": 5.481900324478512, "Erythema ": 4.181759458317539}
\ No newline at end of file
+{"Chest pain": 2.016973804504882, "Hypertension": 2.7295588461459785, "Migraine": 6.688695826128155, "Paraesthesia": 3.029568500740866, "Tinnitus": 5.472886395338049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/420.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/420.json
index 8a353542aaa..ec3ce02ba33 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/420.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/420.json
@@ -1 +1 @@
-{"Chest pain ": 3.4146354594030828, "Haematoma ": 15.381040860995212, "Haemoglobin decreased ": 7.195146414091758, "Haemorrhage intracranial ": 73.12327039440846, "Pulmonary alveolar haemorrhage ": 105.89690505423144, "Thrombocytopenia ": 29.301225320252115}
\ No newline at end of file
+{"Abnormal behaviour": 15.059179866566067, "Aggression": 15.259360716774268, "Agitation": 4.205031584680556, "Alanine aminotransferase increased": 5.166685887179913, "Aspartate aminotransferase increased": 4.207544208629049, "Condition aggravated": 3.055847864664908, "Decreased appetite": 4.6145788105336605, "Diarrhoea": 2.4764853872587063, "Drug ineffective": 2.0475602547385883, "Drug interaction": 5.851466728703322, "Epilepsy": 11.781796004675943, "Gait disturbance": 3.542596030169656, "Generalised tonic-clonic seizure": 9.221365612661124, "Hepatic enzyme increased": 4.403209668746546, "Irritability": 9.332367231185929, "Off label use": 2.0288521454074284, "Overdose": 5.686020081046888, "Product use in unapproved indication": 3.885145001237264, "Sedation": 45.62015425726177, "Seizure": 13.8417682851344, "Somnolence": 8.755493140806944, "Therapeutic response unexpected": 31.182571112175136, "Weight decreased": 2.4581375408619914}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/421.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/421.json
index b0e5ce10bbc..28253dbffcf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/421.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/421.json
@@ -1 +1 @@
-{"Acne ": 2.614319999142741, "Acute respiratory distress syndrome ": 5.644861881524675, "Alanine aminotransferase increased ": 2.584117202608483, "Anaemia ": 2.643481480846501, "Anaphylactic shock ": 2.1832359194945603, "Aspartate aminotransferase increased ": 2.1226259306709823, "Blood bilirubin increased ": 2.170288278862958, "Conjunctivitis ": 8.379775585948028, "Decreased appetite ": 2.335011738588211, "Dehydration ": 2.568889512851261, "Dermatitis ": 3.516965042932214, "Dermatitis acneiform ": 101.74043409911827, "Diarrhoea ": 3.385630733003297, "Disease progression ": 4.171495313099722, "Disseminated intravascular coagulation ": 5.349117565989818, "Dry skin ": 6.654729430906476, "Febrile neutropenia ": 5.136998285102881, "Granulocyte count decreased ": 83.49082057305466, "Granulocytopenia ": 14.45696738715262, "Hypoalbuminaemia ": 12.462634104754642, "Hypocalcaemia ": 15.833808627480296, "Hypokalaemia ": 2.252483852069027, "Hypomagnesaemia ": 46.40220842134673, "Infusion related reaction ": 8.464936897539623, "Interstitial lung disease ": 14.457815572296562, "Intestinal obstruction ": 3.825345488288227, "Leukopenia ": 3.0337516752732925, "Malignant neoplasm progression ": 6.81441490555122, "Metastases to liver ": 3.0853196008628085, "Mucosal inflammation ": 19.15913965359837, "Myelosuppression ": 20.93513213507013, "Neoplasm progression ": 3.1683264039448917, "Neuropathy peripheral ": 7.078778636520931, "Neutropenia ": 8.109531326417507, "Neutrophil count decreased ": 28.17206936855756, "Off label use ": 2.0885846035455584, "Palmar-plantar erythrodysaesthesia syndrome ": 4.934282183697775, "Pancytopenia ": 2.610667183450589, "Paronychia ": 127.35631535512138, "Peripheral sensory neuropathy ": 16.333154170616254, "Platelet count decreased ": 5.716578105321447, "Pneumonia aspiration ": 5.199126358282486, "Pneumothorax ": 5.316058586044711, "Rash ": 2.905174627148421, "Rash pustular ": 10.305356744041344, "Sepsis ": 2.235056544946654, "Septic shock ": 2.504274770731291, "Skin disorder ": 2.270291866888404, "Skin fissures ": 28.77203524874415, "Skin reaction ": 2.747788583345047, "Skin toxicity ": 32.44487531225435, "Staphylococcus test positive ": 64.7901255537391, "Stomatitis ": 12.891272562471556, "Thrombocytopenia ": 3.3410284767093037, "Transaminases increased ": 2.4438038856674806, "White blood cell count decreased ": 17.198878663573115}
\ No newline at end of file
+{"Abdominal pain": 2.3277789678622307, "Haemoglobin decreased": 5.601204371698806, "Hepatic function abnormal": 8.258949751227288, "Myelosuppression": 123.38111695133507, "Neutrophil count decreased": 43.10991943446583, "Off label use": 3.238939377009924, "Platelet count decreased": 11.678395770816712, "Vomiting": 3.3431712680911603, "White blood cell count decreased": 50.06382320888917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/422.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/422.json
index f5930954a7e..958d26bbf93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/422.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/422.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.635559617531791, "Alopecia ": 2.277046277937203, "Anti-cyclic citrullinated peptide antibody positive ": 10.1389882346431, "Arthritis ": 5.078939762959454, "Arthropathy ": 4.703859815865795, "C-reactive protein abnormal ": 10.186203244282844, "C-reactive protein increased ": 9.455318084578147, "Contraindicated product administered ": 3.327097393474024, "Contusion ": 2.4240079212811807, "Discomfort ": 3.4515813647105054, "Drug ineffective ": 3.9820149903148265, "Drug intolerance ": 6.4057197989351184, "Duodenal ulcer perforation ": 12.191558605162614, "Gait disturbance ": 2.1276865835148926, "General physical health deterioration ": 4.67815940857779, "Glossodynia ": 4.241965368332411, "Hand deformity ": 7.842053637448715, "Helicobacter infection ": 10.99665305584431, "Hepatic enzyme increased ": 2.5714108491237915, "Hypersensitivity ": 2.1299344066647152, "Infection ": 4.588255692300145, "Inflammation ": 7.702435262539715, "Infusion related reaction ": 4.352674538718942, "Injury ": 4.908372873509432, "Irritable bowel syndrome ": 11.061700721941204, "Joint swelling ": 9.928168066860168, "Lower respiratory tract infection ": 7.941873051372406, "Maternal exposure during pregnancy ": 2.012687356705128, "Medication error ": 4.28559222115168, "Memory impairment ": 2.0708032605516005, "Muscle injury ": 12.987037467407026, "Musculoskeletal stiffness ": 11.603371470683705, "Neck pain ": 2.2530732233966893, "Osteoarthritis ": 8.688903727005318, "Pain ": 2.9132865134718418, "Pericarditis ": 3.8064003559620194, "Peripheral swelling ": 3.7778105478182895, "Product use issue ": 2.939633641442516, "Productive cough ": 4.276081027261872, "Psoriatic arthropathy ": 6.785098643149864, "Rheumatoid arthritis ": 13.218793550920749, "Sinusitis ": 7.140434726892647, "Swelling ": 5.4602536472805605, "Synovitis ": 35.37116521069708, "Therapeutic product effect decreased ": 14.577250514364772, "Therapeutic product effect incomplete ": 2.246784302922776, "Treatment failure ": 8.157614729260038}
\ No newline at end of file
+{"Abortion": 13.029016481270984, "Abortion induced": 5.778234555351153, "Abortion spontaneous": 2.824132659772705, "Abulia": 28.384495193864304, "Alanine aminotransferase increased": 4.515731423604952, "Amylase increased": 7.52748075588499, "Anaemia": 3.917801383436789, "Anaemia macrocytic": 20.41601545663509, "Ascites": 2.423103024940346, "Aspartate aminotransferase increased": 4.619391561027788, "Atrial septal defect": 7.336026015714461, "Blood HIV RNA increased": 28.836376872901727, "Blood alkaline phosphatase increased": 5.688429452210458, "Blood bilirubin increased": 3.3208884934792406, "Blood creatine phosphokinase increased": 4.994035138708592, "Blood creatinine increased": 2.6522426184794075, "Blood culture positive": 26.825761801253947, "Blood lactate dehydrogenase increased": 5.323866467033643, "Blood lactic acid increased": 36.96344941393885, "Blood triglycerides increased": 7.853861671449067, "Brain death": 15.313579017993831, "Breast enlargement": 10.050274068551545, "Caesarean section": 15.167831135866484, "Candida infection": 2.671800635708834, "Cardiac murmur": 3.982613329617241, "Cardiomyopathy": 4.148974458859302, "Central nervous system lymphoma": 38.90920211271096, "Cerebral toxoplasmosis": 90.456990882979, "Cholestasis": 2.3943419227750757, "Coronary artery disease": 2.7273975375667847, "Depressive symptom": 7.813857619497842, "Developmental delay": 8.526011797102349, "Diabetes mellitus": 8.010185872004477, "Disorientation": 2.6282082386729706, "Disseminated intravascular coagulation": 2.0704977563861364, "Drug resistance": 3.809719538367165, "Dyslipidaemia": 4.8798026076846375, "Facial wasting": 197.20698136397948, "Failure to thrive": 14.384959634017967, "Foetal exposure during pregnancy": 7.530997689333515, "Foetal growth restriction": 5.410604103513777, "Gamma-glutamyltransferase increased": 6.249540266558678, "Guillain-Barre syndrome": 2.279550551440222, "Haemophagocytic lymphohistiocytosis": 5.60846677252474, "Hepatic cirrhosis": 10.081449847375742, "Hepatic failure": 5.158185731886874, "Hepatic function abnormal": 3.12602261018401, "Hepatic steatosis": 12.599659604994558, "Hepatitis": 4.135144464804229, "Hepatitis B": 15.767705158215668, "Hepatitis C": 2.395455472995975, "Hepatitis cholestatic": 6.619742538631544, "Hepatitis fulminant": 10.874454746272315, "Hepatomegaly": 8.620628971074215, "Hepatosplenomegaly": 14.536455110451652, "Herpes virus infection": 6.384761337558008, "Hyperbilirubinaemia": 8.815671634720543, "Hypercholesterolaemia": 14.79790248279143, "Hyperlactacidaemia": 45.66328965745541, "Hyperlipidaemia": 2.963032159665238, "Hyperreflexia": 12.526994702101018, "Hyperthyroidism": 2.349197085017803, "Hypertonia": 6.0388137392567, "Hypertriglyceridaemia": 51.79666303790715, "Hypophagia": 2.760550249175187, "Immune reconstitution inflammatory syndrome": 60.00885722172054, "JC virus infection": 38.38209824326554, "Jaundice": 2.042905083610589, "Lactic acidosis": 15.513690838318295, "Leukopenia": 4.604857504176568, "Lipase increased": 9.724482354172173, "Lipoatrophy": 190.60670605547568, "Lipodystrophy acquired": 91.77322139930904, "Live birth": 6.587160846630346, "Locked-in syndrome": 129.8796683858363, "Low birth weight baby": 7.499620128094573, "Lung infiltration": 5.115284128498868, "Lymphoma": 3.4342327172845644, "Macrocytosis": 33.722367037941495, "Metabolic acidosis": 2.752790521771012, "Mycobacterium avium complex infection": 22.917102689188237, "Myocardial infarction": 2.395919733274142, "Nephrolithiasis": 2.301166811838787, "Nervous system disorder": 4.450318610071912, "Neuropathy peripheral": 2.9641047634885505, "Neutropenia": 3.829555382936244, "Oral candidiasis": 4.697492849660551, "Osteonecrosis": 2.667810004557924, "Pancreatitis": 5.453320870769771, "Pancreatitis acute": 2.743474523763604, "Pancytopenia": 4.667102129145656, "Patent ductus arteriosus": 9.991896921848657, "Pathogen resistance": 7.643189522437596, "Placental disorder": 34.128575768762055, "Pneumocystis jirovecii pneumonia": 9.083205861262153, "Portal hypertension": 18.97363116246328, "Pregnancy": 25.296389568421983, "Premature baby": 7.312124600425434, "Premature delivery": 11.130256088603078, "Premature rupture of membranes": 17.51643184253225, "Progressive multifocal leukoencephalopathy": 17.022703380064378, "Pulmonary hypertension": 3.183165601144518, "Renal impairment": 3.2213529768719487, "Renal tubular necrosis": 8.437768423092422, "Road traffic accident": 3.20995362622218, "Shock": 2.4972995614281515, "Skin ulcer": 2.2922558938832016, "Speech disorder developmental": 12.35470784800599, "Subdural haematoma": 2.282145280074888, "Sudden death": 3.73143393117829, "Tuberculosis": 14.217524984773917, "Varices oesophageal": 35.63120988309785, "Ventricular tachycardia": 2.4952011923170843, "Virologic failure": 7.575623127779882}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/423.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/423.json
index 89209b9f04d..b1969f2358d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/423.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/423.json
@@ -1 +1 @@
-{"Abdominal pain ": 4.317675810106594, "Amenorrhoea ": 2.744479301086959, "Anuria ": 86.87076200210286, "Blood pressure increased ": 2.927533943060538, "Blood pressure measurement ": 88.48518702527767, "Constipation ": 6.208809158321023, "Contraindicated product administered ": 2.3810260812840407, "Cough ": 4.351272880755281, "Device malfunction ": 7.634974583620242, "Diarrhoea ": 2.16412275169804, "Drug ineffective ": 3.9287704909412513, "Drug ineffective for unapproved indication ": 42.24218600054092, "Drug intolerance ": 4.223786170108659, "Dyspepsia ": 13.2799086976483, "Extrapyramidal disorder ": 60.99521700526485, "Eye pain ": 2.568265196173149, "Fibromyalgia ": 4.311736226389039, "Head discomfort ": 4.594867889050179, "Migraine ": 22.81362551475834, "Migraine without aura ": 173.33544977004564, "Muscle spasms ": 2.310143198258543, "Myocardial oedema ": 248.40339966835413, "Neck pain ": 2.195195366040987, "Neovascularisation ": 1602.3203926596684, "Off label use ": 2.125172872971256, "Paradoxical drug reaction ": 303.9100530685184, "Photophobia ": 10.02704189224825, "Photopsia ": 19.81779697081929, "Poor quality sleep ": 7.247337913942489, "Product use issue ": 2.1036369800162222, "Raynaud's phenomenon ": 55.37720285797511, "Respiratory disorder ": 6.717266146899371, "Reversible cerebral vasoconstriction syndrome ": 84.96753267042453, "Swelling face ": 2.5246848672073106, "Therapeutic product effect decreased ": 2.475058937947217, "Therapeutic product effect incomplete ": 2.4787135928912334, "Treatment failure ": 17.35214544419118, "Weight decreased ": 5.705046965155704}
\ No newline at end of file
+{"Abdominal pain": 4.483985858295148, "Anaemia": 6.181664173220954, "Anti-erythropoietin antibody negative": 675.2947513744114, "Anti-erythropoietin antibody positive": 349.5703420902292, "Aplasia pure red cell": 210.8803792217742, "Bone marrow failure": 17.292079470352064, "Bone pain": 2.433837319595624, "Deep vein thrombosis": 2.58090204766743, "Device interaction": 9632.533523763224, "Diarrhoea": 2.6991118965615204, "Drug ineffective": 2.3623826025758823, "Drug specific antibody absent": 143.78375634679756, "Exposure during pregnancy": 2.7412136027599825, "Foetal exposure during pregnancy": 4.360072085638552, "Haematocrit decreased": 9.229948820867802, "Haemoglobin decreased": 11.75485243820902, "Hypersensitivity": 6.2048405343566255, "Hypotension": 5.979994365803763, "Live birth": 21.275077080012537, "Low birth weight baby": 13.5985602262372, "Maternal exposure during pregnancy": 4.690423265148625, "Myelodysplastic syndrome": 12.66255227373563, "Neutralising antibodies positive": 361.4433936119351, "Platelet count decreased": 12.326939414657756, "Premature baby": 8.7230998826782, "Premature delivery": 14.321792496065203, "Premature rupture of membranes": 56.56878537110124, "Therapeutic response decreased": 9.214228158083106, "Transfusion": 24.32321647747281}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/424.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/424.json
index b13724793a8..0055b169e68 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/424.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/424.json
@@ -1 +1 @@
-{"Alopecia ": 3.04218782886829, "Anaemia ": 2.1406881740119044, "Asthenia ": 3.5859065693956387, "Breast cancer ": 7.494784919849463, "Breast cancer metastatic ": 56.213053812705134, "Disease progression ": 7.941998077327304, "Encephalitis herpes ": 454.3821086037361, "Febrile neutropenia ": 8.331747686386285, "Hepatic function abnormal ": 3.96687279735733, "Immunosuppression ": 103.42939245317604, "Interstitial lung disease ": 3.844302313135437, "Malignant neoplasm progression ": 16.817078574147903, "Metastases to bone ": 25.38961047309413, "Metastases to central nervous system ": 29.157739427233377, "Metastases to liver ": 35.45978175461751, "Myelosuppression ": 19.91577679508041, "Neoplasm progression ": 9.50096419372044, "Neuropathy peripheral ": 11.194772262742456, "Neutropenia ": 9.113234767801876, "Neutrophil count decreased ": 14.58383321600367, "Platelet count decreased ": 5.1369529092422965, "Pleural effusion ": 8.976950703173097, "Protein total increased ": 183.550213263826, "White blood cell count decreased ": 8.747986864174766}
\ No newline at end of file
+{"Drug ineffective": 5.437789150840884, "Drug ineffective for unapproved indication": 107.71962629765838, "Factor VIII inhibition": 284.07402197546674, "Haemorrhage": 35.604339240848724}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/425.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/425.json
index 9e26dfeeb6e..0f127c9568e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/425.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/425.json
@@ -1 +1 @@
-{}
\ No newline at end of file
+{"Chest pain": 3.4146354594030828, "Haematoma": 15.381040860995212, "Haemoglobin decreased": 7.195146414091758, "Haemorrhage intracranial": 73.12327039440846, "Pulmonary alveolar haemorrhage": 105.89690505423144, "Thrombocytopenia": 29.298467249143343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/426.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/426.json
index c916a9803b3..4320fea6fd9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/426.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/426.json
@@ -1 +1 @@
-{"Agranulocytosis ": 2.359840747130188, "Blood pressure systolic increased ": 2.989071122070139, "Blood thyroid stimulating hormone increased ": 6.171918724559681, "Blood triglycerides increased ": 2.954688166576865, "Cardiac failure ": 4.307459486215716, "Death ": 6.427121627956616, "Decreased appetite ": 2.425839623796797, "Dementia ": 2.9628039732118605, "Dermatitis allergic ": 2.5803450660117644, "Dermatitis exfoliative ": 12.692730411205076, "Dermatitis exfoliative generalised ": 15.82085825707848, "Disease progression ": 3.370860777925614, "Drug eruption ": 12.93590459405275, "Drug reaction with eosinophilia and systemic symptoms ": 9.465834980422398, "Dry skin ": 3.2248995108482728, "Dysphagia ": 3.2847993241693287, "Eczema ": 3.123227063737258, "Eosinophil count increased ": 9.165166724221438, "Erythema multiforme ": 8.62791842080411, "Fall ": 2.487953405077965, "Hospitalisation ": 2.01637817523183, "Hot flush ": 9.656146846893924, "Hypertension ": 2.608399803391388, "Hypothyroidism ": 9.61074919584059, "Interstitial lung disease ": 11.244950130255395, "Metastases to bone ": 13.247050129787748, "Metastases to lymph nodes ": 6.249677927040783, "Neoplasm malignant ": 2.164180853164125, "Oedema peripheral ": 2.464220997558076, "Prescribed underdose ": 8.501462338724695, "Prostate cancer ": 30.266294219724717, "Prostate cancer metastatic ": 211.62250043889804, "Prostatic specific antigen increased ": 83.62774384057815, "Rash ": 15.042335653212865, "Rash erythematous ": 4.299384290660118, "Rash maculo-papular ": 9.02704790942666, "Rash papular ": 2.353534581936578, "Rash pruritic ": 9.094641264583297, "Skin disorder ": 3.0769161763195068, "Skin exfoliation ": 3.586851519869861, "Skin reaction ": 6.59459687899933, "Skin toxicity ": 12.22907542915095, "Stevens-Johnson syndrome ": 9.09402242960422, "Surgery ": 2.164993423318131, "Therapeutic product effect incomplete ": 2.052843602200828, "Toxic epidermal necrolysis ": 13.41073305438618, "Toxic skin eruption ": 3.77506470746466, "Treatment noncompliance ": 4.188343084493764}
\ No newline at end of file
+{"Acne": 2.614319999142741, "Acute respiratory distress syndrome": 5.644861881524675, "Alanine aminotransferase increased": 2.584117202608483, "Anaemia": 2.643481480846501, "Anaphylactic shock": 2.1832359194945603, "Aspartate aminotransferase increased": 2.1226259306709823, "Blood bilirubin increased": 2.170288278862958, "Conjunctivitis": 8.379775585948028, "Decreased appetite": 2.3349890798320154, "Dehydration": 2.5687523425243786, "Dermatitis": 3.5165048428713432, "Dermatitis acneiform": 101.74043409911827, "Diarrhoea": 3.385602458442467, "Disease progression": 4.171495313099722, "Disseminated intravascular coagulation": 5.349117565989818, "Dry skin": 6.654729430906476, "Febrile neutropenia": 5.136998285102881, "Granulocyte count decreased": 83.49082057305466, "Granulocytopenia": 14.452791677852453, "Hypoalbuminaemia": 12.462634104754642, "Hypocalcaemia": 15.833808627480296, "Hypokalaemia": 2.252483852069027, "Hypomagnesaemia": 46.40220842134673, "Infusion related reaction": 8.464936897539623, "Interstitial lung disease": 14.457815572296562, "Intestinal obstruction": 3.825345488288227, "Leukopenia": 3.0333690903973984, "Malignant neoplasm progression": 6.81441490555122, "Metastases to liver": 3.0853196008628085, "Mucosal inflammation": 19.15913965359837, "Myelosuppression": 20.93513213507013, "Neoplasm progression": 3.1683264039448917, "Neuropathy peripheral": 7.078563424153889, "Neutropenia": 8.109181989218968, "Neutrophil count decreased": 28.17206936855756, "Off label use": 2.088502309147853, "Palmar-plantar erythrodysaesthesia syndrome": 4.934282183697775, "Pancytopenia": 2.610667183450589, "Paronychia": 127.35631535512138, "Peripheral sensory neuropathy": 16.333154170616254, "Platelet count decreased": 5.716578105321447, "Pneumonia aspiration": 5.199126358282486, "Pneumothorax": 5.316058586044711, "Rash": 2.905134696925006, "Rash pustular": 10.305356744041344, "Sepsis": 2.235056544946654, "Septic shock": 2.504274770731291, "Skin disorder": 2.270291866888404, "Skin fissures": 28.77203524874415, "Skin reaction": 2.747788583345047, "Skin toxicity": 32.39811789861671, "Staphylococcus test positive": 64.7901255537391, "Stomatitis": 12.891272562471556, "Thrombocytopenia": 3.34071398598011, "Transaminases increased": 2.443654205145791, "White blood cell count decreased": 17.198878663573115}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/427.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/427.json
index 3d0c17c187b..5168e36cfe1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/427.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/427.json
@@ -1 +1 @@
-{"Acquired gene mutation ": 1461.8004258303438, "Disease progression ": 11.602065531649094, "Drug resistance ": 127.23124849934706, "EGFR gene mutation ": 907.5501128216642, "Hepatitis ": 45.456878755849566, "Hepatitis toxic ": 101.07373888247392, "Hepatotoxicity ": 94.12818719282616, "Interstitial lung disease ": 3.105004273415171, "Malignant neoplasm progression ": 25.191557150446386, "Neoplasm progression ": 36.83248526103096, "Off label use ": 3.660056608963096, "Palmar-plantar erythrodysaesthesia syndrome ": 13.580746876506206, "Pancreatitis ": 7.54355080424299, "Product use in unapproved indication ": 2.630763861669177, "Pulmonary embolism ": 19.003612206779547}
\ No newline at end of file
+{"Abdominal discomfort": 2.626341962345948, "Alopecia": 2.269082883326986, "Anti-cyclic citrullinated peptide antibody positive": 10.103535210749172, "Arthritis": 5.06118021101964, "Arthropathy": 4.6874100847383655, "C-reactive protein abnormal": 10.15059560051462, "C-reactive protein increased": 9.422239932639645, "Contraindicated product administered": 3.3154654912536947, "Contusion": 2.4155333192929165, "Discomfort": 3.4395135456138357, "Drug ineffective": 3.9680198873367942, "Drug intolerance": 6.383306562379395, "Duodenal ulcer perforation": 12.148935606893485, "Gait disturbance": 2.120207857489363, "General physical health deterioration": 4.661796386553818, "Glossodynia": 4.2271358903615335, "Hand deformity": 7.814633803474466, "Helicobacter infection": 10.958209909794524, "Hepatic enzyme increased": 2.5624209102227096, "Hypersensitivity": 2.1224840904752043, "Infection": 4.572206398133791, "Inflammation": 7.675106652992172, "Infusion related reaction": 4.337456214834252, "Injury": 4.890504905298653, "Irritable bowel syndrome": 11.0230233690825, "Joint swelling": 9.893409073089524, "Lower respiratory tract infection": 8.493566585372173, "Maternal exposure during pregnancy": 2.005651651587359, "Medication error": 4.270305774016305, "Memory impairment": 2.0635644010479446, "Muscle injury": 12.94164204648183, "Musculoskeletal stiffness": 11.562746225733584, "Neck pain": 2.245197207127247, "Osteoarthritis": 8.6585228748076, "Pain": 2.903053572284134, "Pericarditis": 3.793092758088475, "Peripheral swelling": 3.764592205738767, "Product use issue": 2.929354608233063, "Productive cough": 4.261134224285573, "Psoriatic arthropathy": 6.761380142270425, "Rheumatoid arthritis": 13.17249183248548, "Sinusitis": 7.115464128585474, "Swelling": 5.441147044709014, "Synovitis": 35.24736709455156, "Therapeutic product effect decreased": 14.526241650555152, "Therapeutic product effect incomplete": 2.2389307917658727, "Treatment failure": 8.129077637160064}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/428.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/428.json
index 6a793b50a76..0556d5dcd78 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/428.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/428.json
@@ -1 +1 @@
-{"Clostridium difficile infection ": 36.05915405235726, "Condition aggravated ": 2.5640313461279045, "Confusional state ": 3.6128796141465065, "Cross sensitivity reaction ": 205.13037800670944, "Delirium ": 9.147956580578294, "Drug ineffective ": 3.995585119611569, "Drug interaction ": 3.827202361981588, "Drug intolerance ": 4.326750183684414, "Drug reaction with eosinophilia and systemic symptoms ": 17.272108767290977, "Drug resistance ": 14.928830600133995, "Drug-induced liver injury ": 11.6844180815453, "Hidradenitis ": 209.6121553729037, "Hypotension ": 2.824947923559972, "Macular degeneration ": 23.499619126453133, "Mobility decreased ": 7.119663964112632, "Pathogen resistance ": 36.75798309471927, "Rash maculo-papular ": 7.599847646099263, "Scar ": 47.26430635587062, "Seizure ": 2.9078166495155826, "Skin lesion ": 18.363471439040357, "Skin odour abnormal ": 151.6783115345313, "Suicidal ideation ": 4.3421375079959725, "Treatment failure ": 9.848499797022344, "Wound secretion ": 213.8818134471567}
\ No newline at end of file
+{"Abdominal pain": 4.317675810106594, "Amenorrhoea": 2.744479301086959, "Anuria": 86.87076200210286, "Blood pressure increased": 2.927482551613363, "Blood pressure measurement": 88.48518702527767, "Constipation": 6.208809158321023, "Contraindicated product administered": 2.3810260812840407, "Cough": 4.351232503905602, "Device malfunction": 7.634974583620242, "Diarrhoea": 2.164104687681636, "Drug ineffective": 3.928741436129919, "Drug ineffective for unapproved indication": 42.24218600054092, "Drug intolerance": 4.223786170108659, "Dyspepsia": 13.2799086976483, "Extrapyramidal disorder": 60.99521700526485, "Eye pain": 2.568265196173149, "Fibromyalgia": 4.311736226389039, "Head discomfort": 4.594867889050179, "Migraine": 22.81362551475834, "Migraine without aura": 173.33544977004564, "Muscle spasms": 2.310143198258543, "Myocardial oedema": 248.40339966835413, "Neck pain": 2.195195366040987, "Neovascularisation": 1602.3203926596684, "Off label use": 2.125089155179861, "Paradoxical drug reaction": 303.9100530685184, "Photophobia": 10.026118124329455, "Photopsia": 19.81779697081929, "Poor quality sleep": 7.247337913942489, "Product use issue": 2.1036369800162222, "Raynaud's phenomenon": 55.37720285797511, "Respiratory disorder": 6.717266146899371, "Reversible cerebral vasoconstriction syndrome": 84.96753267042453, "Swelling face": 2.5246848672073106, "Therapeutic product effect decreased": 2.475058937947217, "Therapeutic product effect incomplete": 2.4787135928912334, "Treatment failure": 17.35214544419118, "Weight decreased": 5.705046965155704}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/429.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/429.json
index 90d2a94be04..b757076fa0e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/429.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/429.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 3.8408930056094417, "Abdominal pain upper ": 2.5936633399688853, "Abnormal loss of weight ": 3.4065076003331902, "Acute respiratory failure ": 4.170461716051188, "Aortic aneurysm ": 6.36972424897701, "Appetite disorder ": 4.022294128035956, "Arteriosclerosis coronary artery ": 4.78500364079098, "Back injury ": 5.726245555203179, "Blood sodium decreased ": 4.045479122789641, "Brain neoplasm ": 2.0762734982602757, "Bronchitis ": 3.724276470447661, "Carbon dioxide increased ": 13.032532561579837, "Cardiac disorder ": 2.516440021759985, "Chest injury ": 8.853499990347881, "Chronic obstructive pulmonary disease ": 2.0358884471745107, "Chronic respiratory failure ": 16.04220473756539, "Constipation ": 2.5909421280546607, "Coronavirus infection ": 4.509321401296473, "Cough ": 3.023753929094348, "Cystitis ": 3.119046808669999, "Death ": 19.13302431129602, "Decreased appetite ": 6.434424581359943, "Diverticulitis ": 2.553161991828615, "Dry skin ": 3.751695226407764, "Dyspepsia ": 6.984396402429972, "Dyspnoea ": 2.3212403501405063, "Dyspnoea exertional ": 3.68963994656675, "Eructation ": 3.86903561573624, "Fall ": 2.15841525780157, "Feeding disorder ": 2.587783881382597, "Fibrosis ": 6.724899520768648, "Flatulence ": 3.69649103657628, "Forced vital capacity decreased ": 65.95745051705178, "Frustration tolerance decreased ": 2.8389036981061, "Gastrointestinal disorder ": 5.004814634191738, "Gastrooesophageal reflux disease ": 3.655058888598689, "Haemoptysis ": 3.423276868722763, "Heart valve incompetence ": 8.613462482769634, "Hernia ": 2.7973538346685576, "Hiatus hernia ": 2.212733849698695, "Hip fracture ": 2.4463346411128035, "Hyperchlorhydria ": 9.085421203680363, "Hypersomnia ": 2.149587151394568, "Hypophagia ": 2.218603879228362, "Hypoxia ": 3.453480625970981, "Idiopathic pulmonary fibrosis ": 159.16530838165005, "Ill-defined disorder ": 2.504100589141831, "Intentional product use issue ": 3.957210026587711, "International normalised ratio decreased ": 7.824526782903493, "Liver function test increased ": 2.214722562796281, "Lower respiratory tract infection ": 2.2308969863372776, "Lung diffusion test decreased ": 48.41025827995069, "Lung disorder ": 4.762604899535714, "Lung neoplasm ": 11.491905384648074, "Lung neoplasm malignant ": 5.6301948807497375, "Nasopharyngitis ": 2.228947970105952, "Nephrolithiasis ": 2.4740732542418216, "Oxygen saturation decreased ": 10.037274736203733, "Painful respiration ": 3.9207854413148793, "Photosensitivity reaction ": 42.81341624115025, "Pneumonia ": 6.188464690501511, "Pneumothorax ": 7.325428863737445, "Productive cough ": 6.254026131592322, "Pulmonary arterial hypertension ": 2.014364389498221, "Pulmonary fibrosis ": 10.172533765134656, "Pulmonary function test abnormal ": 34.56912328079721, "Pulmonary function test decreased ": 29.52444949458685, "Pulmonary hypertension ": 4.035586343209769, "Pulmonary oedema ": 2.9314609956326847, "Pulmonary pain ": 2.865370167294917, "Pulmonary thrombosis ": 4.371943654493496, "Rales ": 2.6413737004021782, "Respiratory disorder ": 3.012641738759477, "Respiratory failure ": 4.339606971047851, "Respiratory tract infection ": 3.218197350828289, "Rib fracture ": 2.731369791669115, "Secretion discharge ": 2.4721614474067963, "Sinus congestion ": 3.036420690062744, "Sinus disorder ": 2.092473032193897, "Skin cancer ": 2.956989328932642, "Skin discolouration ": 2.074626399166184, "Skin exfoliation ": 4.484367857591661, "Skin reaction ": 2.764968930462558, "Solar dermatitis ": 35.13612112450818, "Spinal fracture ": 3.0525121170706724, "Sputum discoloured ": 2.458611805945425, "Sunburn ": 48.76534194596079, "Taste disorder ": 2.501379468890061, "Transaminases increased ": 2.208255895342464, "Upper respiratory tract congestion ": 12.127159172464966, "Urinary tract infection ": 2.6492060212044946, "Walking aid user ": 7.902613951037277, "Walking distance test abnormal ": 52.48563694473251, "Weight decreased ": 7.55394360682067}
\ No newline at end of file
+{"Alopecia": 3.04218782886829, "Anaemia": 2.1406881740119044, "Asthenia": 3.5857639212072896, "Breast cancer": 7.494784919849463, "Breast cancer metastatic": 56.213053812705134, "Disease progression": 7.941998077327304, "Encephalitis herpes": 454.3821086037361, "Febrile neutropenia": 8.331747686386285, "Hepatic function abnormal": 3.96687279735733, "Immunosuppression": 103.42939245317604, "Interstitial lung disease": 3.844302313135437, "Malignant neoplasm progression": 16.817078574147903, "Metastases to bone": 25.38961047309413, "Metastases to central nervous system": 29.157739427233377, "Metastases to liver": 35.45978175461751, "Myelosuppression": 19.91577679508041, "Neoplasm progression": 9.50096419372044, "Neuropathy peripheral": 11.194432297278295, "Neutropenia": 9.112842764385674, "Neutrophil count decreased": 14.58383321600367, "Platelet count decreased": 5.1369529092422965, "Pleural effusion": 8.97612409416455, "Protein total increased": 183.550213263826, "White blood cell count decreased": 8.747986864174766}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/43.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/43.json
index d93147056a7..e5c57f7ad28 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/43.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/43.json
@@ -1 +1 @@
-{"Drug hypersensitivity ": 13.348327111296932, "Peripheral swelling ": 6.617030366243652, "Surgery ": 51.45540116473992}
\ No newline at end of file
+{"Drug interaction": 5.481900324478512, "Erythema": 4.181718560292917}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/430.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/430.json
index 2f461add49d..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/430.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/430.json
@@ -1 +1 @@
-{"Drug resistance ": 236.10679660195305, "Suicidal ideation ": 84.48162649632071}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/431.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/431.json
index 60ba54adafe..090bd1ee41d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/431.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/431.json
@@ -1 +1 @@
-{"Drug ineffective ": 5.093629950035385, "Off label use ": 5.2902055899497205, "Seizure ": 16.27583576751202}
\ No newline at end of file
+{"Agranulocytosis": 2.359840747130188, "Blood pressure systolic increased": 2.989071122070139, "Blood thyroid stimulating hormone increased": 6.171918724559681, "Blood triglycerides increased": 2.954688166576865, "Cardiac failure": 4.307065761689159, "Death": 6.427121627956616, "Decreased appetite": 2.4258160754294766, "Dementia": 2.9628039732118605, "Dermatitis allergic": 2.5803450660117644, "Dermatitis exfoliative": 12.692730411205076, "Dermatitis exfoliative generalised": 15.82085825707848, "Disease progression": 3.370860777925614, "Drug eruption": 12.93590459405275, "Drug reaction with eosinophilia and systemic symptoms": 9.465050809935, "Dry skin": 3.2248995108482728, "Dysphagia": 3.2847993241693287, "Eczema": 3.123227063737258, "Eosinophil count increased": 9.165166724221438, "Erythema multiforme": 8.62791842080411, "Fall": 2.487889578730258, "Hospitalisation": 2.01637817523183, "Hot flush": 9.656146846893924, "Hypertension": 2.608372853281947, "Hypothyroidism": 9.61074919584059, "Interstitial lung disease": 11.244950130255395, "Metastases to bone": 13.247050129787748, "Metastases to lymph nodes": 6.249677927040783, "Neoplasm malignant": 2.164180853164125, "Oedema peripheral": 2.464160055891117, "Prescribed underdose": 8.501462338724695, "Prostate cancer": 30.266294219724717, "Prostate cancer metastatic": 211.62250043889804, "Prostatic specific antigen increased": 83.62774384057815, "Rash": 15.042127923185822, "Rash erythematous": 4.299384290660118, "Rash maculo-papular": 9.02704790942666, "Rash papular": 2.353274452009106, "Rash pruritic": 9.094641264583297, "Skin disorder": 3.0769161763195068, "Skin exfoliation": 3.586851519869861, "Skin reaction": 6.59459687899933, "Skin toxicity": 12.211511580330514, "Stevens-Johnson syndrome": 9.09402242960422, "Surgery": 2.164993423318131, "Therapeutic product effect incomplete": 2.052843602200828, "Toxic epidermal necrolysis": 13.41073305438618, "Toxic skin eruption": 3.77506470746466, "Treatment noncompliance": 4.188343084493764}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/432.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/432.json
index b95b58b74b9..5f8c0a7c62e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/432.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/432.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.532660524676507, "Abdominal pain lower ": 9.95289940394091, "Abortion spontaneous ": 4.303600445537499, "Acne ": 5.843786208510593, "Adenomyosis ": 184.05825029246887, "Alanine aminotransferase increased ": 9.562365114975655, "Alopecia ": 4.349739511118661, "Amenorrhoea ": 17.975812491780623, "Aspartate aminotransferase increased ": 4.820145516433019, "Blood alkaline phosphatase increased ": 2.2014919438860185, "Blood cholesterol increased ": 3.48969124913066, "Breast cancer ": 2.2236743958010665, "Breast discomfort ": 22.96720578288431, "Breast pain ": 2.988441351431604, "Condition aggravated ": 2.6316441507530794, "Deep vein thrombosis ": 2.775890462735965, "Degeneration of uterine leiomyoma ": 6549.056260896661, "Drug-induced liver injury ": 2.246817455591321, "Dry mouth ": 2.185215850047372, "Endometrial adenocarcinoma ": 131.67294194371905, "Endometrial cancer ": 60.53331518222216, "Endometrial hyperplasia ": 449.8768029927492, "Endometrial thickening ": 694.6384135973799, "Flatulence ": 3.319764778317203, "Gamma-glutamyltransferase increased ": 14.908905864081284, "Haemangioma of liver ": 99.47312502887094, "Haemorrhage ": 2.41273149424914, "Heavy menstrual bleeding ": 3.937071567551048, "Hepatic enzyme increased ": 9.362555270490866, "Hepatic steatosis ": 7.925074418281881, "Hot flush ": 8.709152827239416, "Hypertransaminasaemia ": 11.116753889695987, "Intentional product use issue ": 19.525537612815267, "Intercepted product administration error ": 478.3268084470686, "Intermenstrual bleeding ": 5.503489464216597, "Labelled drug-drug interaction medication error ": 17.051385948802324, "Liver disorder ": 2.5057395282185007, "Liver function test abnormal ": 5.086456913606974, "Liver function test increased ": 6.076845977151445, "Maternal exposure before pregnancy ": 27.08950782560163, "Maternal exposure during pregnancy ": 2.3331818032683858, "Menometrorrhagia ": 15.82191013257609, "Mood swings ": 6.707144644639451, "Musculoskeletal pain ": 3.7393132635546578, "Ovarian cyst ": 43.09269855841772, "Pelvic pain ": 15.667663094590742, "Procedural complication ": 122.33656821287612, "Procedural haemorrhage ": 30.69483207240664, "Product administration error ": 14.64511411024511, "Pulmonary embolism ": 2.250017182493361, "Sarcoma uterus ": 887.0831012578955, "Transaminases increased ": 31.35775348740564, "Urinary incontinence ": 12.266455029975042, "Uterine haemorrhage ": 258.4913001725645, "Uterine leiomyoma ": 213.51712604834225, "Uterine leiomyoma necrosis ": 9645.11397923189, "Uterine myoma expulsion ": 5290.646315414552, "Uterine polyp ": 118.51616196599598, "Vaginal discharge ": 13.615477879323098, "Vaginal haemorrhage ": 10.216193869335347, "Vertigo ": 2.849356552112286, "Weight increased ": 3.4774879890319927}
\ No newline at end of file
+{"Acquired gene mutation": 1461.8004258303438, "Disease progression": 11.602065531649094, "Drug resistance": 127.23124849934706, "EGFR gene mutation": 907.5501128216642, "Hepatitis": 45.456878755849566, "Hepatitis toxic": 101.07373888247392, "Hepatotoxicity": 94.12818719282616, "Interstitial lung disease": 3.105004273415171, "Malignant neoplasm progression": 25.191557150446386, "Neoplasm progression": 36.83248526103096, "Off label use": 3.659912440518247, "Palmar-plantar erythrodysaesthesia syndrome": 13.580746876506206, "Pancreatitis": 7.54355080424299, "Product use in unapproved indication": 2.630681826785493, "Pulmonary embolism": 19.003612206779547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/433.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/433.json
index e3d5421b64c..4e7047491bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/433.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/433.json
@@ -1 +1 @@
-{"Abdominal pain lower ": 2.0938787412789925, "Acute kidney injury ": 8.693510529778885, "Adjustment disorder ": 15.268603145473364, "Affect lability ": 4.142772892000246, "Agranulocytosis ": 2.2987826791316937, "Anaemia macrocytic ": 10.613359171990984, "Aphthous ulcer ": 2.548313943292091, "Areflexia ": 27.869898043038837, "Arthritis ": 2.184613741701468, "Aspergillus infection ": 4.91561016242736, "Atelectasis ": 8.568907302197651, "Bile duct stone ": 14.208921112027156, "Blood pressure diastolic abnormal ": 20.007416103556096, "Blood pressure diastolic decreased ": 6.814384765010442, "Blood pressure systolic abnormal ": 20.35462290700057, "Blood pressure systolic increased ": 4.59373021950755, "Blood sodium increased ": 19.54787531681773, "Blood test abnormal ": 3.846413447961888, "Blood urea decreased ": 37.75534749967666, "Brain scan abnormal ": 370.049138546544, "Breath sounds abnormal ": 7.647203144882404, "Cardiogenic shock ": 2.0568882141465634, "Carpal tunnel syndrome ": 4.559309149915089, "Cerebral artery thrombosis ": 139.14963079593562, "Cholestasis ": 5.365756542957679, "Chondropathy ": 25.659009496854104, "Chronic fatigue syndrome ": 4.435906274568137, "Chronic sinusitis ": 5.115054897442563, "Clostridium difficile colitis ": 3.758479670239105, "Coma scale abnormal ": 6.426202186288534, "Completed suicide ": 3.9238201297491737, "Concussion ": 14.395775859399857, "Cutaneous vasculitis ": 3.151614592849884, "Dehydration ": 2.128004273215487, "Delirium ": 3.097002846081021, "Disease recurrence ": 2.617283852208753, "Drug eruption ": 2.120937576076269, "Drug interaction ": 5.776522052262055, "Drug level increased ": 3.4827426274030016, "Drug reaction with eosinophilia and systemic symptoms ": 5.357720300893071, "Drug-induced liver injury ": 3.0521509343829667, "Ejection fraction ": 15.696630541394146, "Electrocardiogram QT prolonged ": 2.201830748755588, "Eosinophilia ": 3.7998942047229662, "Erdheim-Chester disease ": 3599.1438851289136, "Eye haemorrhage ": 2.770930800760256, "FEV1/FVC ratio abnormal ": 464.32046200070266, "Facial paralysis ": 4.414511469384312, "Feeling of body temperature change ": 2.530023739496978, "Fibromyalgia ": 2.508346861358289, "Flatulence ": 2.144860094268031, "Forced expiratory volume abnormal ": 153.74561439498896, "Frequent bowel movements ": 2.0136444136330525, "Fungal infection ": 3.241946779004328, "Gamma-glutamyltransferase increased ": 2.4268568895820968, "Gastrooesophageal reflux disease ": 2.660388133778673, "Haematocrit decreased ": 2.2959368742897643, "Haemoglobin decreased ": 2.065888897318612, "Haemolytic anaemia ": 2.864394408483126, "Heart rate decreased ": 2.1067836539002034, "Hemiplegia ": 15.051830953169755, "Hepatic cytolysis ": 5.936194455305411, "Hepatitis cholestatic ": 5.1740598082943725, "Hepatocellular injury ": 4.238009404699844, "Hip fracture ": 2.195249154858371, "Hydronephrosis ": 22.722424141571256, "Hyperkalaemia ": 3.05422954871171, "Hypocalcaemia ": 4.315871481939196, "Hypomagnesaemia ": 11.301567551637548, "Hyponatraemia ": 6.1934911328850415, "Inappropriate antidiuretic hormone secretion ": 4.68695369620357, "Incorrect product administration duration ": 2.3999916659435976, "Increased appetite ": 2.501307115515281, "Injection site extravasation ": 8.281916500075894, "Intentional overdose ": 12.269213907308025, "Intervertebral disc disorder ": 12.922795790440302, "Iron deficiency ": 64.45286160110963, "Ischaemic stroke ": 6.762726789423836, "Lactic acidosis ": 4.460404056707669, "Lymphoedema ": 4.770843793537126, "Lymphoma ": 3.873476774973775, "Major depression ": 101.11756952010852, "Malnutrition ": 6.876028483988614, "Metabolic acidosis ": 47.04828479884403, "Motor dysfunction ": 4.934519683934377, "Multi-organ disorder ": 26.712879623594432, "Multiple organ dysfunction syndrome ": 2.3906239330462835, "Muscle atrophy ": 4.087823959316461, "Muscle spasticity ": 6.060979420579608, "Neuroleptic malignant syndrome ": 11.86522508139484, "Normal newborn ": 8.50720724557446, "Obstructive airways disorder ": 2.097997070885026, "Oesophagitis ": 5.102870786981723, "Oral lichen planus ": 56.02847417416725, "Pancreatitis acute ": 7.175900814347076, "Papillary thyroid cancer ": 59.179539972509694, "Patent ductus arteriosus ": 11.78958046933987, "Pericardial effusion ": 2.5573390850603825, "Personality disorder ": 16.45643956581091, "Photopsia ": 4.334321809544095, "Physical deconditioning ": 152.45535552702785, "Pleural effusion ": 3.36544633749827, "Polycystic ovaries ": 28.03127236743863, "Portal vein thrombosis ": 6.199317682575309, "Premature baby ": 2.491312112019289, "Protein total decreased ": 8.992006964143311, "Pseudodementia ": 215.6324427323596, "Pulmonary hypertension ": 2.539047318102392, "Rash maculo-papular ": 3.4752048904599184, "Respiratory distress ": 4.006151180557453, "Respiratory failure ": 2.267793047291853, "Rhabdomyolysis ": 7.04782341843211, "Rhinitis allergic ": 5.4439130683398655, "Sedation ": 4.098304803508921, "Sensitisation ": 16.793746205359273, "Serotonin syndrome ": 34.30555816168346, "Skin ulcer ": 16.85275523465684, "Sleep apnoea syndrome ": 4.18688484368344, "Sleep disorder due to a general medical condition ": 2.448396840811888, "Sudden death ": 2.201333354742532, "Suicide attempt ": 12.107441516949448, "Tenosynovitis ": 9.150863003963302, "Therapeutic product effect incomplete ": 2.499211104418301, "Thyroid disorder ": 3.087644340943386, "Toxic epidermal necrolysis ": 3.1705875715707443, "Toxicity to various agents ": 3.2299977469305428, "Tubulointerstitial nephritis ": 10.229963824484969, "Unresponsive to stimuli ": 2.403354240811701, "Vitamin B12 deficiency ": 11.927802543359984}
\ No newline at end of file
+{"Clostridium difficile infection": 35.99342939746824, "Condition aggravated": 2.5593573374858924, "Confusional state": 3.6062914374958535, "Cross sensitivity reaction": 204.75663956831136, "Delirium": 9.131286815894953, "Drug ineffective": 3.9882457584265913, "Drug interaction": 3.8202219049946256, "Drug intolerance": 4.318865805556666, "Drug reaction with eosinophilia and systemic symptoms": 17.239199096755485, "Drug resistance": 14.90162324672444, "Drug-induced liver injury": 11.662410027738362, "Hidradenitis": 209.23020093874217, "Hypotension": 2.819731932572324, "Macular degeneration": 23.45679727338528, "Mobility decreased": 7.106690230525437, "Pathogen resistance": 36.691019677560085, "Rash maculo-papular": 7.585997135634495, "Scar": 47.17817987609707, "Seizure": 2.902192425810229, "Skin lesion": 18.330004567941774, "Skin odour abnormal": 151.4019220382776, "Suicidal ideation": 4.334225090481754, "Treatment failure": 9.830544779573245, "Wound secretion": 213.49207905415952}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/434.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/434.json
index 26dbf408656..c4243f43978 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/434.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/434.json
@@ -1 +1 @@
-{"Ankylosing spondylitis ": 17.687758158197074, "Arthritis ": 2.194497127806509, "Bronchitis ": 3.1556564677496084, "Condition aggravated ": 2.862439595385037, "Drug ineffective ": 5.44452129121055, "Drug ineffective for unapproved indication ": 8.014931198548112, "Drug intolerance ": 3.074957687058699, "Drug specific antibody ": 118.6208654256426, "Dry eye ": 11.645524700313649, "Fibrosis ": 46.537228323332975, "Gait inability ": 6.314367742740171, "Gastric haemorrhage ": 14.295689138236703, "Gastrointestinal disorder ": 2.758593164817002, "Ill-defined disorder ": 4.136068713236246, "Inflammation ": 8.211937068420342, "Infusion related reaction ": 2.755980402086721, "Joint swelling ": 6.734660466452948, "Lower respiratory tract infection ": 7.993038953770923, "Metabolic surgery ": 135.73418500554973, "Mobility decreased ": 3.1574895531528955, "Mouth ulceration ": 5.967306600523477, "Musculoskeletal stiffness ": 4.673732889500736, "Pancytopenia ": 3.1591460241836087, "Pharyngitis ": 23.03344890703354, "Product use in unapproved indication ": 2.035284267643749, "Psoriatic arthropathy ": 5.280557119405412, "Renal cyst ": 16.668164453284717, "Rheumatoid arthritis ": 5.631322626424913, "Sleep apnoea syndrome ": 15.490376288416511, "Synovitis ": 7.351519167574231, "Therapeutic product effect decreased ": 4.728010150576854, "Therapeutic product effect incomplete ": 2.193100388495488, "Toothache ": 20.25336712824321, "Treatment failure ": 5.132143088343799, "Urinary tract infection ": 2.926756893845459, "Vasculitis ": 6.094589287386944, "Vitiligo ": 46.50624058279444}
\ No newline at end of file
+{"Abdominal discomfort": 3.855172944370256, "Abdominal pain upper": 2.5928424966139656, "Abnormal loss of weight": 3.40542994981012, "Acute respiratory failure": 4.169142276140492, "Aortic aneurysm": 6.3677091319236485, "Appetite disorder": 4.021021655977103, "Arteriosclerosis coronary artery": 4.783489840720489, "Back injury": 5.724433932889856, "Blood sodium decreased": 4.04419923185147, "Brain neoplasm": 2.075616677912593, "Bronchitis": 3.722873917202113, "Carbon dioxide increased": 13.028409758277713, "Cardiac disorder": 2.515643789310562, "Cardiac failure congestive": 2.013054359045229, "Chest injury": 8.850699210365187, "Chronic obstructive pulmonary disease": 2.0352443159235345, "Chronic respiratory failure": 16.037129809495376, "Constipation": 2.5901222028172524, "Coronavirus infection": 4.507894849881883, "Cough": 3.022768685307924, "Cystitis": 3.118060009756329, "Death": 19.126960025029927, "Decreased appetite": 6.432324458567986, "Diverticulitis": 2.5523542382089084, "Dry skin": 3.750508179036716, "Dyspepsia": 6.982185933392133, "Dyspnoea": 2.3236725586412934, "Dyspnoea exertional": 3.6884725150864113, "Eructation": 3.8678115856977193, "Fall": 2.157676736494821, "Feeding disorder": 2.586965187055508, "Fibrosis": 6.722772049541165, "Flatulence": 3.6950198829615095, "Forced vital capacity decreased": 65.93658430880326, "Frustration tolerance decreased": 2.838005618234625, "Gastrointestinal disorder": 5.003072346300518, "Gastrooesophageal reflux disease": 3.65390233318248, "Haemoptysis": 3.4221937689463164, "Heart valve incompetence": 8.610737610937539, "Hernia": 2.7964688782164453, "Hiatus hernia": 2.2120338347273583, "Hip fracture": 2.445560689560902, "Hyperchlorhydria": 9.08254707134164, "Hypersomnia": 2.1489070888387083, "Hypophagia": 2.217901996431225, "Hypoxia": 3.452387950531525, "Idiopathic pulmonary fibrosis": 160.12044965908808, "Ill-defined disorder": 2.5033083173049677, "Intentional product use issue": 3.955957866924915, "International normalised ratio decreased": 7.822051364246144, "Liver function test increased": 2.214021878383813, "Lower respiratory tract infection": 2.230191158419984, "Lung diffusion test decreased": 48.39494354424976, "Lung disorder": 4.761097913472248, "Lung neoplasm": 11.488269917644, "Lung neoplasm malignant": 5.6284134464195965, "Nasopharyngitis": 2.228072477659746, "Nephrolithiasis": 2.472880589338075, "Oxygen saturation decreased": 10.033555098270156, "Painful respiration": 3.9195451110955695, "Photosensitivity reaction": 42.79986465523282, "Pneumonia": 6.186505368729088, "Pneumothorax": 7.323111164010298, "Productive cough": 6.2520471776498034, "Pulmonary arterial hypertension": 2.013727135491629, "Pulmonary fibrosis": 10.169314943310932, "Pulmonary function test abnormal": 34.55818621173127, "Pulmonary function test decreased": 29.515108095434044, "Pulmonary hypertension": 4.034309557336277, "Pulmonary oedema": 2.9301475046574064, "Pulmonary pain": 2.864463701596189, "Pulmonary thrombosis": 4.370560536414549, "Rales": 2.6405380964200096, "Respiratory disorder": 3.011688579061909, "Respiratory failure": 4.337873811246519, "Respiratory tract infection": 3.217179197535148, "Rib fracture": 2.7305056769596114, "Secretion discharge": 2.4713793777075663, "Sinus congestion": 3.035460126221565, "Sinus disorder": 2.0918110836836696, "Skin cancer": 2.9560538632412907, "Skin discolouration": 2.073970032156693, "Skin exfoliation": 4.482948938869258, "Skin reaction": 2.764094156532044, "Solar dermatitis": 35.12500578326797, "Spinal fracture": 3.051546410273425, "Sputum discoloured": 2.457834026460564, "Sunburn": 48.74991258560205, "Taste disorder": 2.500588054247004, "Transaminases increased": 2.207421725688703, "Upper respiratory tract congestion": 12.123322780975297, "Urinary tract infection": 2.648367730078509, "Walking aid user": 7.900113911840121, "Walking distance test abnormal": 52.4690334259277, "Weight decreased": 7.551552086664238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/435.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/435.json
index fa44cd9b02f..a29c8631781 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/435.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/435.json
@@ -1 +1 @@
-{"Anaemia ": 6.528893855488719, "Thrombocytopenia ": 5.687978020880372}
\ No newline at end of file
+{"Drug resistance": 236.10679660195305, "Suicidal ideation": 84.48162649632071}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/436.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/436.json
index c72186f1bc7..7246f8f9489 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/436.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/436.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.796479139298581, "Abdominal pain upper ": 3.803817952370124, "Acute kidney injury ": 5.737531314237847, "Alanine aminotransferase increased ": 2.839805805747653, "Amylase increased ": 29.46604981944361, "Angioedema ": 4.353967507455475, "Anuria ": 7.084855627102629, "Blister ": 5.564323440104054, "Blood glucose abnormal ": 4.7680095273092045, "Blood glucose increased ": 3.7479470361611016, "Cholestasis ": 2.4232999562892514, "Chromaturia ": 4.015750077957812, "Coma ": 2.111216858542408, "Dermatitis bullous ": 24.383506259140844, "Diabetes mellitus inadequate control ": 6.844122069330457, "Diarrhoea ": 2.153592239024237, "Dysphagia ": 2.4359430013814727, "Eczema ": 3.4967921072958306, "Eosinophilia ": 3.235380510740385, "Flatulence ": 4.133856811584389, "Gamma-glutamyltransferase increased ": 8.70891737749009, "Glycosylated haemoglobin increased ": 20.25568493182673, "Hepatic cytolysis ": 3.6749664536199433, "Hepatic steatosis ": 5.053654039446934, "Hepatitis ": 3.5073875534566032, "Hyperglycaemia ": 3.517447406920152, "Hyperkalaemia ": 10.712512431115888, "Hypoglycaemia ": 7.1271169551344205, "Hypothermia ": 7.131139310790509, "Jaundice ": 4.055669878212297, "Lactic acidosis ": 54.0076132996157, "Lipase increased ": 67.63168697118317, "Metabolic acidosis ": 12.854079728363898, "Oedema peripheral ": 2.233242635202733, "Pancreatic carcinoma ": 25.51502488151719, "Pancreatic carcinoma metastatic ": 13.566853639311631, "Pancreatitis ": 12.53858841408445, "Pancreatitis acute ": 23.31092100895109, "Pemphigoid ": 101.41832654564612, "Pemphigus ": 2.385749495898354, "Pruritus ": 2.62907971593626, "Scratch ": 14.68221026310497, "Shock ": 3.8966614155691, "Skin exfoliation ": 3.014405639842455, "Tachypnoea ": 3.4290015117298958, "Transaminases increased ": 7.1391336025862735, "Weight decreased ": 3.4346742377569863}
\ No newline at end of file
+{"Drug ineffective": 5.09359229857572, "Off label use": 5.289997241235013, "Seizure": 16.274031542937973}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/437.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/437.json
index 979bfe6ffeb..3bf095d1c9a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/437.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/437.json
@@ -1 +1 @@
-{"Toxic epidermal necrolysis ": 1310.0945573625113}
\ No newline at end of file
+{"Abdominal distension": 2.532660524676507, "Abdominal pain lower": 9.95289940394091, "Abortion spontaneous": 4.303600445537499, "Acne": 5.843786208510593, "Adenomyosis": 184.05825029246887, "Alanine aminotransferase increased": 9.562365114975655, "Alopecia": 4.349739511118661, "Amenorrhoea": 17.975812491780623, "Aspartate aminotransferase increased": 4.820145516433019, "Blood alkaline phosphatase increased": 2.2014919438860185, "Blood cholesterol increased": 3.48969124913066, "Breast cancer": 2.2236743958010665, "Breast discomfort": 22.96720578288431, "Breast pain": 2.988441351431604, "Condition aggravated": 2.6316441507530794, "Deep vein thrombosis": 2.775890462735965, "Degeneration of uterine leiomyoma": 6549.056260896661, "Drug-induced liver injury": 2.2466805163052403, "Dry mouth": 2.185215850047372, "Endometrial adenocarcinoma": 131.67294194371905, "Endometrial cancer": 60.53331518222216, "Endometrial hyperplasia": 449.8768029927492, "Endometrial thickening": 694.6384135973799, "Flatulence": 3.3194948905355632, "Gamma-glutamyltransferase increased": 14.908905864081284, "Haemangioma of liver": 99.47312502887094, "Haemorrhage": 2.41273149424914, "Heavy menstrual bleeding": 3.937071567551048, "Hepatic enzyme increased": 9.362555270490866, "Hepatic steatosis": 7.925074418281881, "Hot flush": 8.709152827239416, "Hypertransaminasaemia": 11.116753889695987, "Intentional product use issue": 19.525537612815267, "Intercepted product administration error": 478.3268084470686, "Intermenstrual bleeding": 5.503489464216597, "Labelled drug-drug interaction medication error": 17.051385948802324, "Liver disorder": 2.5057395282185007, "Liver function test abnormal": 5.086456913606974, "Liver function test increased": 6.076845977151445, "Maternal exposure before pregnancy": 27.08950782560163, "Maternal exposure during pregnancy": 2.3331818032683858, "Menometrorrhagia": 15.82191013257609, "Mood swings": 6.707144644639451, "Musculoskeletal pain": 3.7393132635546578, "Ovarian cyst": 43.09269855841772, "Pelvic pain": 15.667663094590742, "Procedural complication": 122.33656821287612, "Procedural haemorrhage": 30.69483207240664, "Product administration error": 14.643964181496422, "Pulmonary embolism": 2.250017182493361, "Sarcoma uterus": 887.0831012578955, "Transaminases increased": 31.355822057843337, "Urinary incontinence": 12.266455029975042, "Uterine haemorrhage": 258.4913001725645, "Uterine leiomyoma": 213.51712604834225, "Uterine leiomyoma necrosis": 9645.11397923189, "Uterine myoma expulsion": 5290.646315414552, "Uterine polyp": 118.51616196599598, "Vaginal discharge": 13.615477879323098, "Vaginal haemorrhage": 10.216193869335347, "Vertigo": 2.849356552112286, "Weight increased": 3.4774879890319927}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/438.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/438.json
index 288cefdb719..1f7a1d7ee87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/438.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/438.json
@@ -1 +1 @@
-{"Accident ": 5.144035107094759, "Acute myocardial infarction ": 7.325563270362159, "Angina pectoris ": 5.096299573872878, "Aortic dissection ": 43.391853880427526, "Arrhythmia ": 2.9160239852004186, "Atrial fibrillation ": 2.734237611659318, "Atypical femur fracture ": 213.41435445724005, "Atypical fracture ": 224.31030932772043, "Blood alkaline phosphatase increased ": 2.774168954891828, "Blood calcium decreased ": 13.234423592449104, "Blood calcium increased ": 8.554528081514452, "Blood parathyroid hormone increased ": 36.13298525304862, "Bone density abnormal ": 84.08274061974352, "Bone disorder ": 3.775575725507248, "Bone pain ": 3.3556331403174613, "Cardiac failure ": 8.142897428970938, "Cardiac failure acute ": 3.824127992436815, "Cardiac valve disease ": 6.364659014219273, "Cerebellar haemorrhage ": 9.53038046414173, "Cerebral haemorrhage ": 6.3443704720361405, "Cerebral infarction ": 37.763819754613, "Cerebrovascular accident ": 3.477571262860085, "Colon cancer ": 3.350564067893551, "Compression fracture ": 111.38521889177213, "Dementia ": 6.38362169263948, "Device issue ": 2.773834576914907, "Drug effect less than expected ": 11.829188906857402, "Fall ": 12.933825815671687, "Femoral neck fracture ": 109.3183785369566, "Femur fracture ": 55.55938056204546, "Foot fracture ": 3.732413956682307, "Fracture ": 110.43387424951868, "Groin pain ": 6.792578362636017, "Haemorrhagic stroke ": 3.578442986039483, "Hip fracture ": 11.528819794365058, "Humerus fracture ": 33.35886865017544, "Hypercalcaemia ": 8.224792986348008, "Hypocalcaemia ": 20.622950207417933, "Ill-defined disorder ": 6.089371274751175, "Incorrect dose administered ": 4.0870254340427525, "Injection site bruising ": 3.1019959216213184, "Injection site erythema ": 2.879290018259928, "Injection site mass ": 4.571729353193205, "Injection site swelling ": 2.986074547492431, "Intentional dose omission ": 6.336179286098685, "Intracranial aneurysm ": 11.291548026712093, "Ischaemic cerebral infarction ": 22.582858916587057, "Ischaemic stroke ": 2.5693306780159952, "Lacunar infarction ": 33.699373431212905, "Loose tooth ": 17.923837666594252, "Lower limb fracture ": 3.490797371104312, "Lumbar vertebral fracture ": 76.62288260096102, "Lung neoplasm malignant ": 2.529412716010654, "Lymphoma ": 2.698702429827353, "Marasmus ": 87.59384467418964, "Myocardial infarction ": 5.414172495557952, "Osteomyelitis ": 5.840069245667778, "Osteonecrosis of jaw ": 79.22637126581128, "Pain in jaw ": 3.2613983174053947, "Parkinson's disease ": 2.926948208048838, "Pathological fracture ": 48.53169007781396, "Pelvic fracture ": 26.831616776128005, "Physical deconditioning ": 15.201333457368364, "Pneumonia aspiration ": 5.000132700453898, "Polymyalgia rheumatica ": 3.645073409048223, "Product administration interrupted ": 30.2334681074962, "Pseudarthrosis ": 261.59813408667446, "Radius fracture ": 101.206244799868, "Renal impairment ": 4.384872013152113, "Rib fracture ": 5.490175872880482, "Spinal compression fracture ": 98.82642522688928, "Spinal disorder ": 7.167093533958791, "Spinal fracture ": 70.15579788005445, "Spinal operation ": 9.317071321301713, "Stress fracture ": 17.55122792646365, "Subarachnoid haemorrhage ": 7.950975202226571, "Subdural haematoma ": 3.341747108730501, "Sudden death ": 4.108090162567711, "Surgery ": 3.5739627670567877, "Thalamus haemorrhage ": 16.490124475169907, "Therapy interrupted ": 6.469732792247984, "Thoracic vertebral fracture ": 118.69884794778946, "Tibia fracture ": 9.020705761638062, "Tooth disorder ": 6.273600837694171, "Tooth extraction ": 17.492160552502018, "Tooth infection ": 6.41678709579727, "Transient ischaemic attack ": 8.15057614678674, "Unevaluable event ": 7.291176011995714, "Upper limb fracture ": 7.887001755859747, "Wrist fracture ": 11.054667842951089}
\ No newline at end of file
+{"Abdominal pain lower": 2.093560023308759, "Acute kidney injury": 8.692185631951418, "Adjustment disorder": 15.266279122472952, "Affect lability": 4.142142297541798, "Agranulocytosis": 2.298432727642905, "Anaemia macrocytic": 10.611743755698138, "Aphthous ulcer": 2.547926061609027, "Areflexia": 27.86565535883756, "Arthritis": 2.184281163993944, "Aspergillus infection": 4.914861960065954, "Atelectasis": 8.56760290466052, "Bile duct stone": 14.206758430730549, "Blood pressure diastolic abnormal": 20.004370824312385, "Blood pressure diastolic decreased": 6.813347562816841, "Blood pressure systolic abnormal": 20.35152478039202, "Blood pressure systolic increased": 4.593030952004533, "Blood sodium increased": 19.544899919126408, "Blood test abnormal": 3.845827975270725, "Blood urea decreased": 37.74960057265469, "Brain scan abnormal": 369.9928078142119, "Breath sounds abnormal": 7.646039111482623, "Cardiogenic shock": 2.056575136199732, "Carpal tunnel syndrome": 4.558615165557465, "Cerebral artery thrombosis": 139.12844813425593, "Cholestasis": 5.364939659629719, "Chondropathy": 25.655103962356492, "Chronic fatigue syndrome": 4.435231080521956, "Chronic sinusitis": 5.114276306638289, "Clostridium difficile colitis": 3.757907576573632, "Coma scale abnormal": 6.425224079691463, "Completed suicide": 3.9232226087944686, "Concussion": 14.393584506310788, "Cutaneous vasculitis": 3.151134897988244, "Dehydration": 2.127566601053628, "Delirium": 3.096531357873908, "Disease recurrence": 2.616885450166313, "Drug eruption": 2.1206147171472027, "Drug interaction": 5.775641966617146, "Drug level increased": 3.482212468310215, "Drug reaction with eosinophilia and systemic symptoms": 5.356461103240522, "Drug-induced liver injury": 3.051500041405652, "Ejection fraction": 15.69424139496607, "Electrocardiogram QT prolonged": 2.201495558849452, "Eosinophilia": 3.799315730217822, "Erdheim-Chester disease": 3598.596093268954, "Eye haemorrhage": 2.7705090300515733, "FEV1/FVC ratio abnormal": 464.2497912425585, "Facial paralysis": 4.41383940769813, "Feeling of body temperature change": 2.5296386458452327, "Fibromyalgia": 2.507965038436624, "Flatulence": 2.1443591543183342, "Forced expiratory volume abnormal": 153.72221324368624, "Frequent bowel movements": 2.0133379178023363, "Fungal infection": 3.2405529213131743, "Gamma-glutamyltransferase increased": 2.4264874459659787, "Gastrooesophageal reflux disease": 2.6599831062599555, "Haematocrit decreased": 2.2955874036431307, "Haemoglobin decreased": 2.0655743613878355, "Haemolytic anaemia": 2.863958411436394, "Heart rate decreased": 2.106462965639234, "Hemiplegia": 15.04953935896331, "Hepatic cytolysis": 5.935290657852606, "Hepatitis cholestatic": 5.173272214966265, "Hepatocellular injury": 4.236129141174011, "Hip fracture": 2.1949150068811307, "Hydronephrosis": 22.71896492943059, "Hyperkalaemia": 3.053342947532353, "Hypocalcaemia": 4.315214533170031, "Hypomagnesaemia": 11.29984711343156, "Hyponatraemia": 6.192547871112337, "Inappropriate antidiuretic hormone secretion": 4.686240256111195, "Incorrect product administration duration": 2.399626364403326, "Increased appetite": 2.5009263969898465, "Injection site extravasation": 8.280655928387487, "Intentional overdose": 12.26734475450065, "Intervertebral disc disorder": 12.920828820535943, "Iron deficiency": 64.44304810144143, "Ischaemic stroke": 6.761697231437221, "Lactic acidosis": 4.459724969156753, "Lymphoedema": 4.770117625973984, "Lymphoma": 3.872887182904488, "Major depression": 101.10216788144834, "Malnutrition": 6.874981845884314, "Metabolic acidosis": 47.041116391867455, "Motor dysfunction": 4.9337685733766605, "Multi-organ disorder": 26.70881359727129, "Multiple organ dysfunction syndrome": 2.3902600103538933, "Muscle atrophy": 4.087201747226432, "Muscle spasticity": 6.058483298729239, "Neuroleptic malignant syndrome": 11.863418489686396, "Normal newborn": 8.50591234195522, "Obstructive airways disorder": 2.0976777357808083, "Oesophagitis": 5.102094065738626, "Oral lichen planus": 56.01994590351213, "Pancreatitis acute": 7.174808179816264, "Papillary thyroid cancer": 59.17053071577792, "Patent ductus arteriosus": 11.787785913576451, "Pericardial effusion": 2.556949807786574, "Personality disorder": 16.453934643661885, "Photopsia": 4.333662084723042, "Physical deconditioning": 152.4321336546522, "Pleural effusion": 3.364623656352942, "Polycystic ovaries": 28.027005435198895, "Portal vein thrombosis": 6.1983741091391495, "Premature baby": 2.4909328729846587, "Protein total decreased": 8.990638327034405, "Pseudodementia": 215.59962289320904, "Pulmonary hypertension": 2.538660839197544, "Rash maculo-papular": 3.474675777902193, "Respiratory distress": 4.005541269138588, "Respiratory failure": 2.267260404584704, "Rhabdomyolysis": 7.046750182093179, "Rhinitis allergic": 5.443084436197959, "Sedation": 4.0976809266558245, "Sensitisation": 16.791189989164966, "Serotonin syndrome": 34.30033247545885, "Skin ulcer": 16.850189085471083, "Sleep apnoea syndrome": 4.184391072232984, "Sleep disorder due to a general medical condition": 2.448024163835955, "Sudden death": 2.200998294560316, "Suicide attempt": 12.105597069637495, "Tenosynovitis": 9.149470188042338, "Therapeutic product effect incomplete": 2.4988306065067403, "Thyroid disorder": 3.087174362446939, "Toxic epidermal necrolysis": 3.1701049301345043, "Toxicity to various agents": 3.229505829785045, "Tubulointerstitial nephritis": 10.228406343167066, "Unresponsive to stimuli": 2.402723968397478, "Vitamin B12 deficiency": 11.92598700138102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/439.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/439.json
index c842d0ac60b..8f64c8ae7b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/439.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/439.json
@@ -1 +1 @@
-{"Ascites ": 2.765764743568304, "Blood alkaline phosphatase increased ": 2.077306977926209, "Blood lactate dehydrogenase increased ": 3.642831200084728, "Blood magnesium decreased ": 13.762875400735172, "Blood phosphorus decreased ": 20.200027659713385, "Blood pressure systolic increased ": 4.777221955175985, "Blood thyroid stimulating hormone increased ": 7.878227121765229, "Blood triglycerides increased ": 7.099972640559061, "Blood urea increased ": 4.669591411647087, "Body temperature decreased ": 5.794183636533713, "Bone pain ": 4.131972932645251, "Breast cancer ": 3.393652508877239, "Breast cancer metastatic ": 39.16397170009321, "Cardiac neoplasm malignant ": 1370.9472851697726, "Cytomegalovirus infection ": 14.298008998173785, "Diabetes mellitus ": 2.82404467931253, "Disease progression ": 5.371173345611446, "Drug interaction ": 2.2737607901536254, "Drug intolerance ": 3.5339743276471687, "Drug level increased ": 2.9005944344684376, "Drug resistance ": 5.273792086447853, "Electrocardiogram ST segment elevation ": 24.214403426721475, "Electrolyte imbalance ": 6.312003765456354, "Eyelid oedema ": 3.2907684808401663, "Gastric haemorrhage ": 5.885428147723778, "Gastric ulcer ": 3.605499057521736, "General physical health deterioration ": 2.265481252832702, "Haematemesis ": 2.177070177769392, "Haemoglobin decreased ": 2.107842887709875, "Haemoptysis ": 2.70950515316095, "Hepatic lesion ": 13.903296751737496, "Hepatic mass ": 29.730763792722183, "Hormone receptor positive breast cancer ": 257.72149654337187, "Hypothyroidism ": 3.953510726380879, "Hypoxia ": 3.7770093858823537, "Immunosuppressant drug level increased ": 27.509769063503462, "Infantile spasms ": 117.93038841103424, "Ingrowing nail ": 55.71051236674529, "Interstitial lung disease ": 3.2609879601867244, "Leukopenia ": 2.981597718104191, "Lung disorder ": 2.732633687773769, "Lung infiltration ": 13.40256776412486, "Malignant neoplasm progression ": 24.097942047331514, "Malignant pleural effusion ": 45.353502992322944, "Metastases to bone ": 44.916092013069736, "Metastases to central nervous system ": 5.909263629848896, "Metastases to kidney ": 201.56682743457355, "Metastases to liver ": 49.40117682104076, "Metastases to lung ": 41.68066664429985, "Metastases to lymph nodes ": 24.873221042092617, "Metastases to skin ": 93.9978510593902, "Metastases to spine ": 24.43880980660968, "Metastasis ": 12.058787052567316, "Metastatic renal cell carcinoma ": 18.240195690993257, "Mouth ulceration ": 5.01274661406502, "Mucosal inflammation ": 11.204110676464571, "Muscle contractions involuntary ": 7.934051166488537, "Myelodysplastic syndrome ": 4.7348508055082, "Needle issue ": 7.632344285518537, "Neoplasm progression ": 8.151092738862795, "Neuroendocrine tumour ": 49.35720273574054, "PIK3CA-activated mutation ": 320.8386037988223, "Palmar-plantar erythrodysaesthesia syndrome ": 7.692662760600868, "Pancreatic neuroendocrine tumour ": 144.42396150719617, "Peripheral sensory neuropathy ": 16.274647361266226, "Pleural effusion ": 2.9858586237120983, "Pneumonitis ": 17.09063871947472, "Product use in unapproved indication ": 2.491957097416866, "Proteinuria ": 2.148518889400526, "Renal cell carcinoma ": 22.852939290475664, "Respiratory failure ": 2.4107765751514867, "Skin discolouration ": 2.0684483389475434, "Stomatitis ": 5.36391854486605, "Supraventricular extrasystoles ": 21.498535698713088, "Tenderness ": 2.49096443730201, "Therapy non-responder ": 2.3991295398331345, "Tumour marker increased ": 19.677953169321498, "Tumour necrosis ": 96.702265388255, "Urosepsis ": 10.178391297599736}
\ No newline at end of file
+{"Ankylosing spondylitis": 17.506190823212762, "Arthritis": 2.171971249831496, "Bronchitis": 3.123075889524972, "Condition aggravated": 2.833030416323528, "Drug ineffective": 5.38839846193546, "Drug ineffective for unapproved indication": 7.932649926938994, "Drug intolerance": 3.0433812461948118, "Drug specific antibody": 117.40307272805944, "Dry eye": 11.52595401748044, "Fibrosis": 46.05946083510741, "Gait inability": 6.249530359631804, "Gastric haemorrhage": 14.148941812547823, "Gastrointestinal disorder": 2.7301832397639587, "Ill-defined disorder": 4.093609534052771, "Inflammation": 8.12717797895624, "Infusion related reaction": 2.7276886368634887, "Joint swelling": 6.665459602666664, "Lower respiratory tract infection": 7.910956692669164, "Metabolic surgery": 134.3409973507636, "Mobility decreased": 3.12507348643454, "Mouth ulceration": 5.906053951647388, "Musculoskeletal stiffness": 4.625727520051438, "Pancytopenia": 3.126710539999196, "Pharyngitis": 22.791669832868497, "Product use in unapproved indication": 2.0143193753238844, "Psoriatic arthropathy": 5.226351376324046, "Renal cyst": 16.4970708529175, "Rheumatoid arthritis": 5.573465511015581, "Sleep apnoea syndrome": 15.32454843707335, "Synovitis": 7.276048476802377, "Therapeutic product effect decreased": 4.679466883949853, "Therapeutic product effect incomplete": 2.170586917274073, "Toothache": 20.045401273482963, "Treatment failure": 5.0794399701627455, "Urinary tract infection": 2.8967042660079345, "Vasculitis": 6.032032983324261, "Vitiligo": 46.02879122375792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/44.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/44.json
index 11d3d4a5d8b..faaca4725bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/44.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/44.json
@@ -1 +1 @@
-{"Application site burn ": 59.00338709100504, "Application site discharge ": 532.9627777471007, "Application site discolouration ": 64.92981737708975, "Application site erosion ": 156.95737222410713, "Application site erythema ": 67.13065316459243, "Application site haemorrhage ": 194.16432212653245, "Application site inflammation ": 364.0892757176776, "Application site irritation ": 63.88590868536174, "Application site pain ": 20.30873062154639, "Application site pruritus ": 34.2725169819962, "Application site reaction ": 90.73690072666808, "Application site scab ": 637.9441892819284, "Application site swelling ": 21.15855554628843, "Application site ulcer ": 1589.5166149094773, "Application site vesicles ": 56.72354895590348, "Burning sensation ": 2.162931599365788, "Dermatitis ": 8.273588094486662, "Dysuria ": 4.322488389978663, "Eczema ": 2.182924149825864, "Erythema ": 3.5086879954571586, "Erythema multiforme ": 13.707163544445548, "Inflammation ": 7.306664193487716, "Influenza like illness ": 6.745198237156695, "Nasal congestion ": 2.02742515866795, "Scab ": 66.07394693788449, "Scar ": 8.408695199011598, "Skin burning sensation ": 9.393943348875805, "Skin disorder ": 3.323494639758008, "Skin erosion ": 23.49579280694612, "Skin exfoliation ": 2.4362292731836748, "Skin irritation ": 17.70122601436196, "Skin lesion ": 4.547923062012956, "Skin reaction ": 11.193033437008417, "Skin ulcer ": 10.211631803541431, "Vitiligo ": 31.379429357719623, "Vulvovaginal burning sensation ": 33.75958637737784, "Wound ": 6.545652792468006}
\ No newline at end of file
+{"Drug hypersensitivity": 13.348327111296932, "Peripheral swelling": 6.617030366243652, "Surgery": 51.45540116473992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/440.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/440.json
index c12754ddc9b..55d82d8e4f4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/440.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/440.json
@@ -1 +1 @@
-{"Drug ineffective ": 2.6186900872924928, "Off label use ": 17.66148311935275, "Product use in unapproved indication ": 18.72836008263974}
\ No newline at end of file
+{"Anaemia": 6.528893855488719, "Thrombocytopenia": 5.6874430137305545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/441.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/441.json
index 39c5e426386..823c97c679e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/441.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/441.json
@@ -1 +1 @@
-{"Drug ineffective ": 2.1015439620872853, "Foetal exposure during pregnancy ": 19.495186980924544, "Maternal exposure during pregnancy ": 19.13131250383814}
\ No newline at end of file
+{"Abdominal pain": 2.796479139298581, "Abdominal pain upper": 3.803817952370124, "Acute kidney injury": 5.737531314237847, "Alanine aminotransferase increased": 2.839805805747653, "Amylase increased": 29.46604981944361, "Angioedema": 4.353967507455475, "Anuria": 7.084855627102629, "Blister": 5.564323440104054, "Blood glucose abnormal": 4.7680095273092045, "Blood glucose increased": 3.7479470361611016, "Cholestasis": 2.4232999562892514, "Chromaturia": 4.015750077957812, "Coma": 2.111216858542408, "Dermatitis bullous": 24.383506259140844, "Diabetes mellitus inadequate control": 6.844122069330457, "Diarrhoea": 2.1535742589768025, "Dysphagia": 2.4359430013814727, "Eczema": 3.4967921072958306, "Eosinophilia": 3.235380510740385, "Flatulence": 4.133520620783561, "Gamma-glutamyltransferase increased": 8.70891737749009, "Glycosylated haemoglobin increased": 20.25568493182673, "Hepatic cytolysis": 3.6749664536199433, "Hepatic steatosis": 5.053654039446934, "Hepatitis": 3.5073875534566032, "Hyperglycaemia": 3.517447406920152, "Hyperkalaemia": 10.711032188906342, "Hypoglycaemia": 7.126876017526011, "Hypothermia": 7.131139310790509, "Jaundice": 4.055669878212297, "Lactic acidosis": 54.0076132996157, "Lipase increased": 67.63168697118317, "Metabolic acidosis": 12.854079728363898, "Oedema peripheral": 2.233187428374045, "Pancreatic carcinoma": 25.51502488151719, "Pancreatic carcinoma metastatic": 13.566853639311631, "Pancreatitis": 12.53858841408445, "Pancreatitis acute": 23.31092100895109, "Pemphigoid": 101.41832654564612, "Pemphigus": 2.385749495898354, "Pruritus": 2.6290478548033582, "Scratch": 14.68221026310497, "Shock": 3.8966614155691, "Skin exfoliation": 3.014405639842455, "Tachypnoea": 3.428513890527847, "Transaminases increased": 7.138695830950886, "Weight decreased": 3.4346742377569863}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/442.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/442.json
index 39f48a2ee7a..91db953029e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/442.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/442.json
@@ -1 +1 @@
-{"Acute myocardial infarction ": 2.234215698031039, "Ankle fracture ": 5.463992749685228, "Blindness unilateral ": 4.39881776632864, "Blood calcium increased ": 5.674320322379011, "Blood cholesterol increased ": 2.552927135125385, "Blood triglycerides increased ": 2.623569961709125, "Body height decreased ": 49.31886112704123, "Bone density decreased ": 3.216952570509279, "Bone disorder ": 4.816449972754821, "Bone pain ": 2.965721220010123, "Breast cancer ": 13.40162752097214, "Breast cancer metastatic ": 3.136122849503648, "Breast cancer recurrent ": 18.46245009646464, "Breast mass ": 9.097949359735118, "Breast swelling ": 4.472314358611604, "Bronchitis ": 3.50988967534229, "Cardiomegaly ": 2.9117040140855046, "Cataract ": 4.3228607882600665, "Cerebral infarction ": 7.776129770855238, "Cerebrovascular accident ": 5.409031730854047, "Cervical vertebral fracture ": 19.61003571433293, "Cholecystectomy ": 6.18790886593593, "Colitis ischaemic ": 8.155575366121688, "Compression fracture ": 76.89606127282046, "Deep vein thrombosis ": 32.65772922721633, "Diverticulum ": 2.9710420481092594, "Embolism ": 46.02814311929044, "Embolism venous ": 66.84597846085978, "Endometrial adenocarcinoma ": 604.4527609197656, "Endometrial cancer ": 231.7981583463173, "Endometrial hyperplasia ": 133.67793517664762, "Eye haemorrhage ": 2.109717247523056, "Fall ": 4.961280978161904, "Fear ": 2.6348847814667944, "Femoral neck fracture ": 8.441538707210738, "Femur fracture ": 18.87786805348156, "Foot deformity ": 2.9655351865267283, "Foot fracture ": 4.799184072330944, "Fracture ": 15.034191178847802, "Gastritis ": 2.2956621388249583, "Glaucoma ": 2.0950632273830974, "Haematocrit decreased ": 2.5157855363644157, "Haemorrhagic stroke ": 4.585353696442629, "Hand fracture ": 3.4995935053658225, "Head injury ": 2.8086317631680355, "Hemiplegia ": 2.4477992012940946, "Hip arthroplasty ": 3.948220905738071, "Hip fracture ": 24.13053188687281, "Hot flush ": 6.528925471053257, "Hypercalcaemia ": 3.0336295083060096, "Injection site bruising ": 18.331199522342416, "Injection site haemorrhage ": 11.61833532103239, "Intervertebral disc degeneration ": 6.5505886250028365, "Intraductal proliferative breast lesion ": 96.14445866869367, "Invasive ductal breast carcinoma ": 38.00910493468018, "Iron deficiency anaemia ": 4.788631727801992, "Ischaemic stroke ": 3.822416497238737, "Knee arthroplasty ": 3.085781417042667, "Kyphosis ": 30.863447269862174, "Lower limb fracture ": 4.120261704848079, "Lumbar vertebral fracture ": 28.93008537881848, "Lymphoma ": 2.3271515831106515, "Mitral valve incompetence ": 3.2761629132493844, "Muscle spasms ": 4.004184488621846, "Oedema peripheral ": 2.173123166553942, "Osteoarthritis ": 2.7356626835918183, "Osteonecrosis of jaw ": 9.774382602494402, "Osteoporosis ": 3.002512697810034, "Osteoporotic fracture ": 13.810657763091127, "Ovarian cancer ": 21.583699905103146, "Patella fracture ": 28.396294877641424, "Pelvic fracture ": 48.499415079187166, "Peripheral swelling ": 2.093672755562276, "Phlebitis ": 4.423161684438792, "Postmenopausal haemorrhage ": 2.676355260641452, "Posture abnormal ": 9.133056824008086, "Pulmonary embolism ": 17.91445464567648, "Pulmonary thrombosis ": 4.563114965574401, "Radius fracture ": 17.456502658096053, "Retinal artery occlusion ": 7.225426963925329, "Retinal haemorrhage ": 9.044511759070131, "Retinal vascular thrombosis ": 47.79861329191732, "Retinal vein occlusion ": 51.98195723432399, "Retinal vein thrombosis ": 110.94061222300276, "Rib fracture ": 10.445020557408972, "Road traffic accident ": 2.626895400609443, "Shoulder fracture ": 6.6465963699851, "Spinal compression fracture ": 24.29755644683253, "Spinal fracture ": 28.279706739843384, "Spinal osteoarthritis ": 5.703154097724782, "Stress fracture ": 20.148786191374477, "Superficial vein thrombosis ": 12.333145398673466, "Surgery ": 3.441008400318584, "Thoracic vertebral fracture ": 79.56931000386388, "Thrombophlebitis ": 8.318057673661865, "Thrombosis ": 6.859674353407695, "Tibia fracture ": 6.8662793905212345, "Tooth disorder ": 3.364914961775102, "Transient ischaemic attack ": 11.788808716874918, "Upper limb fracture ": 4.955706561828708, "Urine output decreased ": 3.013004624283128, "Uterine cancer ": 20.495797464059677, "Uterine leiomyoma ": 10.600438962067017, "Uterine polyp ": 47.071154540269646, "Vaginal haemorrhage ": 2.554002326355911, "Varicose vein ": 11.731844006539845, "Venous thrombosis ": 13.779395982568392, "Venous thrombosis limb ": 10.7266069872005, "Visual acuity reduced ": 2.390287140205289, "Visual field defect ": 2.70299387428394, "Wrist fracture ": 8.692064607518123}
\ No newline at end of file
+{"Toxic epidermal necrolysis": 1310.0945573625113}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/443.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/443.json
index 0e19d2b420d..90c68e7d6df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/443.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/443.json
@@ -1 +1 @@
-{"Blister ": 23.39029526963781, "Lacrimation increased ": 77.51671038697926, "Off label use ": 4.401666709436875, "Onycholysis ": 1639.7553507646785, "Product use in unapproved indication ": 10.895818578399744, "Skin exfoliation ": 47.940157979314, "Visual impairment ": 12.488085687630624}
\ No newline at end of file
+{"Accident": 5.144035107094759, "Acute myocardial infarction": 7.325563270362159, "Angina pectoris": 5.096299573872878, "Aortic dissection": 43.391853880427526, "Arrhythmia": 2.9160239852004186, "Atrial fibrillation": 2.7341628908740456, "Atypical femur fracture": 213.41435445724005, "Atypical fracture": 224.31030932772043, "Blood alkaline phosphatase increased": 2.774168954891828, "Blood calcium decreased": 13.234423592449104, "Blood calcium increased": 8.554528081514452, "Blood parathyroid hormone increased": 36.13298525304862, "Bone density abnormal": 84.08274061974352, "Bone disorder": 3.775575725507248, "Bone pain": 3.3556331403174613, "Cardiac failure": 8.14215124342692, "Cardiac failure acute": 3.824127992436815, "Cardiac valve disease": 6.364659014219273, "Cerebellar haemorrhage": 9.53038046414173, "Cerebral haemorrhage": 6.3443704720361405, "Cerebral infarction": 37.763819754613, "Cerebrovascular accident": 3.477508495812639, "Colon cancer": 3.350564067893551, "Compression fracture": 111.38521889177213, "Dementia": 6.38362169263948, "Device issue": 2.773834576914907, "Drug effect less than expected": 11.829188906857402, "Fall": 12.933492176954132, "Femoral neck fracture": 109.3183785369566, "Femur fracture": 55.55938056204546, "Foot fracture": 3.732413956682307, "Fracture": 110.43387424951868, "Groin pain": 6.792578362636017, "Haemorrhagic stroke": 3.578442986039483, "Hip fracture": 11.528819794365058, "Humerus fracture": 33.35886865017544, "Hypercalcaemia": 8.224792986348008, "Hypocalcaemia": 20.622950207417933, "Ill-defined disorder": 6.089371274751175, "Incorrect dose administered": 4.0870254340427525, "Injection site bruising": 3.1019959216213184, "Injection site erythema": 2.879290018259928, "Injection site mass": 4.571729353193205, "Injection site swelling": 2.986074547492431, "Intentional dose omission": 6.336179286098685, "Intracranial aneurysm": 11.291548026712093, "Ischaemic cerebral infarction": 22.582858916587057, "Ischaemic stroke": 2.5693306780159952, "Lacunar infarction": 33.699373431212905, "Loose tooth": 17.923837666594252, "Lower limb fracture": 3.490797371104312, "Lumbar vertebral fracture": 76.62288260096102, "Lung neoplasm malignant": 2.529412716010654, "Lymphoma": 2.698702429827353, "Marasmus": 87.59384467418964, "Myocardial infarction": 5.414172495557952, "Osteomyelitis": 5.840069245667778, "Osteonecrosis of jaw": 79.22637126581128, "Pain in jaw": 3.2613983174053947, "Parkinson's disease": 2.926948208048838, "Pathological fracture": 48.53169007781396, "Pelvic fracture": 26.831616776128005, "Physical deconditioning": 15.201333457368364, "Pneumonia aspiration": 5.000132700453898, "Polymyalgia rheumatica": 3.645073409048223, "Product administration interrupted": 30.2334681074962, "Pseudarthrosis": 261.59813408667446, "Radius fracture": 101.206244799868, "Renal impairment": 4.384872013152113, "Rib fracture": 5.490175872880482, "Spinal compression fracture": 98.82642522688928, "Spinal disorder": 7.167093533958791, "Spinal fracture": 70.15579788005445, "Spinal operation": 9.317071321301713, "Stress fracture": 17.55122792646365, "Subarachnoid haemorrhage": 7.950975202226571, "Subdural haematoma": 3.341747108730501, "Sudden death": 4.108090162567711, "Surgery": 3.5739627670567877, "Thalamus haemorrhage": 16.490124475169907, "Therapy interrupted": 6.469732792247984, "Thoracic vertebral fracture": 118.69884794778946, "Tibia fracture": 9.020705761638062, "Tooth disorder": 6.273600837694171, "Tooth extraction": 17.492160552502018, "Tooth infection": 6.41678709579727, "Transient ischaemic attack": 8.15057614678674, "Unevaluable event": 7.291176011995714, "Upper limb fracture": 7.887001755859747, "Wrist fracture": 11.054667842951089}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/444.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/444.json
index a10780f0ec5..1218c1caf42 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/444.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/444.json
@@ -1 +1 @@
-{"Acute kidney injury ": 4.224643894893948, "Bacteraemia ": 66.97157870114837, "Bone marrow failure ": 54.64760399084529, "Capillary leak syndrome ": 391.6026821910266, "Hepatic cytolysis ": 36.54017759660096, "Infection ": 7.635305913920701, "Sepsis ": 12.807350071629726}
\ No newline at end of file
+{"Ascites": 2.765764743568304, "Blood alkaline phosphatase increased": 2.077306977926209, "Blood lactate dehydrogenase increased": 3.642831200084728, "Blood magnesium decreased": 13.762875400735172, "Blood phosphorus decreased": 20.200027659713385, "Blood pressure systolic increased": 4.777221955175985, "Blood thyroid stimulating hormone increased": 7.878227121765229, "Blood triglycerides increased": 7.099972640559061, "Blood urea increased": 4.669591411647087, "Body temperature decreased": 5.794183636533713, "Bone pain": 4.131972932645251, "Breast cancer": 3.393652508877239, "Breast cancer metastatic": 39.16397170009321, "Cardiac neoplasm malignant": 1370.9472851697726, "Cytomegalovirus infection": 14.298008998173785, "Diabetes mellitus": 2.82404467931253, "Disease progression": 5.371173345611446, "Drug interaction": 2.2737607901536254, "Drug intolerance": 3.5339743276471687, "Drug level increased": 2.9005944344684376, "Drug resistance": 5.273792086447853, "Electrocardiogram ST segment elevation": 24.214403426721475, "Electrolyte imbalance": 6.312003765456354, "Eyelid oedema": 3.2907684808401663, "Gastric haemorrhage": 5.885428147723778, "Gastric ulcer": 3.603101824266253, "General physical health deterioration": 2.265481252832702, "Haematemesis": 2.176877076703062, "Haemoglobin decreased": 2.107842887709875, "Haemoptysis": 2.70950515316095, "Hepatic lesion": 13.903296751737496, "Hepatic mass": 29.730763792722183, "Hormone receptor positive breast cancer": 257.72149654337187, "Hypothyroidism": 3.953510726380879, "Hypoxia": 3.7770093858823537, "Immunosuppressant drug level increased": 27.509769063503462, "Infantile spasms": 117.93038841103424, "Ingrowing nail": 55.71051236674529, "Interstitial lung disease": 3.2609879601867244, "Leukopenia": 2.9812216886789726, "Lung disorder": 2.732633687773769, "Lung infiltration": 13.40256776412486, "Malignant neoplasm progression": 24.097942047331514, "Malignant pleural effusion": 45.353502992322944, "Metastases to bone": 44.916092013069736, "Metastases to central nervous system": 5.909263629848896, "Metastases to kidney": 201.56682743457355, "Metastases to liver": 49.40117682104076, "Metastases to lung": 41.68066664429985, "Metastases to lymph nodes": 24.873221042092617, "Metastases to skin": 93.9978510593902, "Metastases to spine": 24.43880980660968, "Metastasis": 12.058787052567316, "Metastatic renal cell carcinoma": 18.240195690993257, "Mouth ulceration": 5.01274661406502, "Mucosal inflammation": 11.204110676464571, "Muscle contractions involuntary": 7.934051166488537, "Myelodysplastic syndrome": 4.7348508055082, "Needle issue": 7.632344285518537, "Neoplasm progression": 8.151092738862795, "Neuroendocrine tumour": 49.35720273574054, "PIK3CA-activated mutation": 320.8386037988223, "Palmar-plantar erythrodysaesthesia syndrome": 7.692662760600868, "Pancreatic neuroendocrine tumour": 144.42396150719617, "Peripheral sensory neuropathy": 16.274647361266226, "Pleural effusion": 2.98558359170863, "Pneumonitis": 17.09063871947472, "Product use in unapproved indication": 2.4918793489983444, "Proteinuria": 2.148518889400526, "Renal cell carcinoma": 22.852939290475664, "Respiratory failure": 2.4105774657978736, "Skin discolouration": 2.0684483389475434, "Stomatitis": 5.36391854486605, "Supraventricular extrasystoles": 21.498535698713088, "Tenderness": 2.49096443730201, "Therapy non-responder": 2.398919924607103, "Tumour marker increased": 19.677953169321498, "Tumour necrosis": 96.702265388255, "Urosepsis": 10.178391297599736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/445.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/445.json
index bdd665bdde5..ab100a06aad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/445.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/445.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 10.26560903728218, "Acne ": 3.0727292852334545, "Amenorrhoea ": 2.704875313116577, "Application site burn ": 20.209520669171948, "Application site discolouration ": 76.84951553435127, "Application site erythema ": 41.57151758806449, "Application site hypersensitivity ": 126.4377489659286, "Application site irritation ": 60.05365519160141, "Application site pain ": 5.053048374388454, "Application site pruritus ": 76.49688124651175, "Application site rash ": 74.67275309781097, "Application site reaction ": 38.631953824218456, "Application site vesicles ": 41.520771892426325, "Breast pain ": 6.820687666695131, "Deep vein thrombosis ": 7.039769491270097, "Dermatitis contact ": 17.97830950180935, "Ectopic pregnancy ": 37.73428142583202, "Exposure during pregnancy ": 70.93397111363079, "Fluid retention ": 2.3239544910469445, "Haemorrhage ": 2.6639405214270164, "Inappropriate schedule of product administration ": 7.4254628499864515, "Intermenstrual bleeding ": 13.32914071501503, "Maternal exposure during pregnancy ": 2.973803311670892, "Medication error ": 5.027118328797085, "Menstrual disorder ": 2.0428543868199105, "Mood swings ": 2.8882909445655454, "Polymenorrhoea ": 2.3654009776792018, "Pregnancy ": 12.377603435493102, "Pregnancy with contraceptive patch ": 158247.44099835248, "Product adhesion issue ": 333.66787809081507, "Product administered at inappropriate site ": 53.11866923087421, "Product administration error ": 3.2448183376503827, "Product complaint ": 35.10255332432735, "Product dose omission issue ": 2.2500955044684825, "Product quality issue ": 2.288637478112077, "Product use in unapproved indication ": 2.0362229344253, "Pulmonary embolism ": 8.964385213582462, "Skin irritation ": 18.608065985300453, "Skin reaction ": 4.00291753989474, "Therapeutic response decreased ": 7.472287871091993, "Therapeutic response unexpected ": 2.855973301553378, "Thrombosis ": 3.1250812265411345, "Underdose ": 5.971975249478788, "Unintended pregnancy ": 727.267258337259, "Unwanted pregnancy ": 1551.6748132401951, "Vaginal haemorrhage ": 20.724463402346466, "Wrong technique in product usage process ": 11.930155209492296}
\ No newline at end of file
+{"Drug ineffective": 2.6186707305159405, "Off label use": 17.66078740858096, "Product use in unapproved indication": 18.727776006640703}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/446.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/446.json
index 9162c98cbf3..9688bcaf199 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/446.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/446.json
@@ -1 +1 @@
-{"Hyperkalaemia ": 35.18193331870564, "Off label use ": 3.240885837103567, "Product use issue ": 13.896638095810998, "Sepsis ": 14.29925800453056}
\ No newline at end of file
+{"Drug ineffective": 2.1015284277371453, "Foetal exposure during pregnancy": 19.495186980924544, "Maternal exposure during pregnancy": 19.13131250383814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/447.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/447.json
index 1d5d16066bc..e05b96fd2a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/447.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/447.json
@@ -1 +1 @@
-{"Anaphylactic reaction ": 2.8118731507226715, "Blood pressure increased ": 2.09635426668533, "COVID-19 ": 10.8807155937457, "COVID-19 pneumonia ": 37.67549896918361, "Chest discomfort ": 2.5508285586151263, "Deep vein thrombosis ": 3.1638762042795}
\ No newline at end of file
+{"Acute myocardial infarction": 2.232325945134727, "Ankle fracture": 5.459371210073607, "Blindness unilateral": 4.395097284598544, "Blood calcium increased": 5.669521243400619, "Blood cholesterol increased": 2.5507676414002893, "Blood triglycerides increased": 2.6213510661702606, "Body height decreased": 49.27713546652811, "Bone density decreased": 3.2142303151865432, "Bone disorder": 4.8123761356662085, "Bone pain": 2.963212385264249, "Breast cancer": 13.390285082471236, "Breast cancer metastatic": 3.1334704603262225, "Breast cancer recurrent": 18.44683462053573, "Breast mass": 9.090254398142012, "Breast swelling": 4.468531955798216, "Bronchitis": 3.506709918296062, "Cardiomegaly": 2.909241428022039, "Cataract": 4.319203853472248, "Cerebral infarction": 7.769550889179011, "Cerebrovascular accident": 5.40435606810549, "Cervical vertebral fracture": 19.59345017112809, "Cholecystectomy": 6.182675417725585, "Colitis ischaemic": 8.148677454913416, "Compression fracture": 76.83100643839943, "Deep vein thrombosis": 32.630069314064194, "Diverticulum": 2.9685293535226664, "Embolism": 45.98919886185333, "Embolism venous": 66.78943225919956, "Endometrial adenocarcinoma": 603.9414079145375, "Endometrial cancer": 231.6020401367057, "Endometrial hyperplasia": 133.56486836752222, "Eye haemorrhage": 2.107932962428776, "Fall": 4.956954013736346, "Fear": 2.632656295440559, "Femoral neck fracture": 8.434399314240418, "Femur fracture": 18.86189667832693, "Foot deformity": 2.9630271492477087, "Foot fracture": 4.795124752268973, "Fracture": 15.021470351922598, "Gastritis": 2.2937205032894554, "Glaucoma": 2.0932913185675126, "Haematocrit decreased": 2.513657742006864, "Haemorrhagic stroke": 4.581475543263785, "Hand fracture": 3.494086252448078, "Head injury": 2.806256227341833, "Hemiplegia": 2.445729005863231, "Hip arthroplasty": 3.944881534710202, "Hip fracture": 24.11011271580117, "Hot flush": 6.523401125198133, "Hypercalcaemia": 3.031063779175513, "Injection site bruising": 18.31569071064464, "Injection site haemorrhage": 11.608507023258948, "Intervertebral disc degeneration": 6.545048288501292, "Intraductal proliferative breast lesion": 96.06313467398658, "Invasive ductal breast carcinoma": 37.976951229351, "Iron deficiency anaemia": 4.782881162023502, "Ischaemic stroke": 3.8191833613759454, "Knee arthroplasty": 3.083171556162263, "Kyphosis": 30.83734398551614, "Lower limb fracture": 4.116776823281052, "Lumbar vertebral fracture": 28.90561504067764, "Lymphoma": 2.3251834448219832, "Mitral valve incompetence": 3.2733921116850384, "Muscle spasms": 4.000796010574504, "Oedema peripheral": 2.171230970473777, "Osteoarthritis": 2.7333487465784008, "Osteonecrosis of jaw": 9.76611508895758, "Osteoporosis": 2.9999724015333338, "Osteoporotic fracture": 13.79897771212123, "Ovarian cancer": 21.56544297691745, "Patella fracture": 28.37227801280889, "Pelvic fracture": 48.4583836964676, "Peripheral swelling": 2.09190130801946, "Phlebitis": 4.419420742168093, "Postmenopausal haemorrhage": 2.674091700461756, "Posture abnormal": 9.125332744012123, "Pulmonary embolism": 17.899284454126462, "Pulmonary thrombosis": 4.559255692432718, "Radius fracture": 17.44173877223233, "Retinal artery occlusion": 7.219316153187682, "Retinal haemorrhage": 9.03686149142727, "Retinal vascular thrombosis": 47.758186534802206, "Retinal vein occlusion": 51.93797886780008, "Retinal vein thrombosis": 110.84675997302188, "Rib fracture": 10.43618475420748, "Road traffic accident": 2.624673542708273, "Shoulder fracture": 6.640975097307915, "Spinal compression fracture": 24.277002145931487, "Spinal fracture": 28.2557794538092, "Spinal osteoarthritis": 5.698330632482849, "Stress fracture": 20.131744991307844, "Superficial vein thrombosis": 12.322713388550582, "Surgery": 3.438097913876999, "Thoracic vertebral fracture": 79.50200247377553, "Thrombophlebitis": 8.31102206815091, "Thrombosis": 6.853869553233903, "Tibia fracture": 6.86047238571675, "Tooth disorder": 3.3620690707780847, "Transient ischaemic attack": 11.778833715242884, "Upper limb fracture": 4.951515103283462, "Urine output decreased": 3.0104564407669736, "Uterine cancer": 20.47846108275617, "Uterine leiomyoma": 10.591473603925976, "Uterine polyp": 47.03134338984493, "Vaginal haemorrhage": 2.551841988688668, "Varicose vein": 11.72192109213458, "Venous thrombosis": 13.76774051244228, "Venous thrombosis limb": 10.71753438044166, "Visual acuity reduced": 2.3882654895133584, "Visual field defect": 2.7007078279673, "Wrist fracture": 8.68471255513968}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/448.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/448.json
index 5e8dda835e8..6d772ac5f98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/448.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/448.json
@@ -1 +1 @@
-{"Feeling abnormal ": 20.667155510802168}
\ No newline at end of file
+{"Blister": 23.39029526963781, "Lacrimation increased": 77.51671038697926, "Off label use": 4.401493356474914, "Onycholysis": 1639.7553507646785, "Product use in unapproved indication": 10.895478829038847, "Skin exfoliation": 47.940157979314, "Visual impairment": 12.488085687630624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/449.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/449.json
index a63001dccb5..16b7eb0035d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/449.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/449.json
@@ -1 +1 @@
-{"Aggression ": 8.75118043909636, "Agitation ": 7.554911944167258, "Atrioventricular block ": 14.675575961666516, "Blood pressure decreased ": 2.6559787471888487, "Bradycardia ": 14.38727758371703, "Cognitive disorder ": 4.520162761715218, "Confusional state ": 3.632108723154914, "Dehydration ": 2.1841061512066373, "Dementia Alzheimer's type ": 47.43302399078536, "Drug interaction ": 3.3808627833316325, "Epilepsy ": 5.025424609617815, "Fall ": 6.732621621765509, "General physical health deterioration ": 2.61303145239608, "Hallucination ": 9.084379473408289, "Hepatic cytolysis ": 5.121763974210132, "Hyponatraemia ": 3.1644517546599444, "Hypotension ": 2.322177342759317, "Loss of consciousness ": 3.422250403130506, "Memory impairment ": 3.766492137692678, "Orthostatic hypotension ": 7.95395390542175, "Restlessness ": 3.482875786032762, "Somnolence ": 3.2077006540019144, "Speech disorder ": 3.3351590841194314, "Syncope ": 3.38005165759865, "Urinary incontinence ": 7.123450693544794, "Urinary tract infection ": 3.859158954182993, "Wrong technique in product usage process ": 3.25153303923832}
\ No newline at end of file
+{"Acute kidney injury": 4.224643894893948, "Bacteraemia": 66.97157870114837, "Bone marrow failure": 54.64760399084529, "Capillary leak syndrome": 391.6026821910266, "Hepatic cytolysis": 36.54017759660096, "Infection": 7.635305913920701, "Sepsis": 12.807350071629726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/45.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/45.json
index 3c8fa641cb1..5cef14d902d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/45.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/45.json
@@ -1 +1 @@
-{"Constipation ": 8.640128677945562, "Drug interaction ": 5.997742681229084, "Interstitial lung disease ": 19.73846127964552}
\ No newline at end of file
+{"Application site burn": 58.905979843581655, "Application site discharge": 532.9627777471007, "Application site discolouration": 64.92981737708975, "Application site erosion": 156.95737222410713, "Application site erythema": 67.11979005014729, "Application site haemorrhage": 194.16432212653245, "Application site inflammation": 364.0892757176776, "Application site irritation": 63.88590868536174, "Application site pain": 20.30630379720485, "Application site pruritus": 34.2725169819962, "Application site reaction": 90.73690072666808, "Application site scab": 634.0270679650852, "Application site swelling": 21.15855554628843, "Application site ulcer": 1589.5166149094773, "Application site vesicles": 56.72354895590348, "Burning sensation": 2.162931599365788, "Dermatitis": 8.27250449425426, "Dysuria": 4.322488389978663, "Eczema": 2.182924149825864, "Erythema": 3.508653657525994, "Erythema multiforme": 13.707163544445548, "Inflammation": 7.306293880697874, "Influenza like illness": 6.745198237156695, "Nasal congestion": 2.02742515866795, "Scab": 66.05235409489354, "Scar": 8.408695199011598, "Skin burning sensation": 9.393943348875805, "Skin disorder": 3.323494639758008, "Skin erosion": 23.49579280694612, "Skin exfoliation": 2.4362292731836748, "Skin irritation": 17.70122601436196, "Skin lesion": 4.547923062012956, "Skin reaction": 11.193033437008417, "Skin ulcer": 10.211631803541431, "Vitiligo": 31.379429357719623, "Vulvovaginal burning sensation": 33.75958637737784, "Wound": 6.54505246652725}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/450.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/450.json
index 3c1f2a5c0b0..e5467879862 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/450.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/450.json
@@ -1 +1 @@
-{"Acute kidney injury ": 9.28166861438496, "Decreased appetite ": 3.4396751949980957, "Weight decreased ": 5.429548847765617}
\ No newline at end of file
+{"Abortion spontaneous": 10.26560903728218, "Acne": 3.0727292852334545, "Amenorrhoea": 2.704875313116577, "Application site burn": 20.17642007110197, "Application site discolouration": 76.84951553435127, "Application site erythema": 41.56481712396383, "Application site hypersensitivity": 126.4377489659286, "Application site irritation": 60.05365519160141, "Application site pain": 5.052446358825056, "Application site pruritus": 76.49688124651175, "Application site rash": 74.67275309781097, "Application site reaction": 38.631953824218456, "Application site vesicles": 41.520771892426325, "Breast pain": 6.820687666695131, "Deep vein thrombosis": 7.039769491270097, "Dermatitis contact": 17.97830950180935, "Ectopic pregnancy": 37.73428142583202, "Exposure during pregnancy": 70.93397111363079, "Fluid retention": 2.3239544910469445, "Haemorrhage": 2.6639405214270164, "Inappropriate schedule of product administration": 7.4254628499864515, "Intermenstrual bleeding": 13.32914071501503, "Maternal exposure during pregnancy": 2.973803311670892, "Medication error": 5.026757359173626, "Menstrual disorder": 2.0428543868199105, "Mood swings": 2.8882909445655454, "Polymenorrhoea": 2.3654009776792018, "Pregnancy": 12.377603435493102, "Pregnancy with contraceptive patch": 158247.44099835248, "Product adhesion issue": 333.66787809081507, "Product administered at inappropriate site": 53.11866923087421, "Product administration error": 3.2445641172422026, "Product complaint": 35.10255332432735, "Product dose omission issue": 2.2500955044684825, "Product quality issue": 2.288637478112077, "Product use in unapproved indication": 2.036159416731394, "Pulmonary embolism": 8.964385213582462, "Skin irritation": 18.608065985300453, "Skin reaction": 4.00291753989474, "Therapeutic response decreased": 7.472287871091993, "Therapeutic response unexpected": 2.855973301553378, "Thrombosis": 3.1250812265411345, "Underdose": 5.971975249478788, "Unintended pregnancy": 727.267258337259, "Unwanted pregnancy": 1551.6748132401951, "Vaginal haemorrhage": 20.724463402346466, "Wrong technique in product usage process": 11.930155209492296}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/451.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/451.json
index bb098692001..4810e8fc483 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/451.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/451.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.3754092024919373, "Angina pectoris ": 2.862233653237765, "Angioedema ": 2.980556821838915, "Anuria ": 2.5336996573190254, "Aortic aneurysm ": 6.873072114304232, "Aortic arteriosclerosis ": 5.060357905848247, "Aortic valve incompetence ": 4.628532070591958, "Arrhythmia ": 3.1963046096998564, "Arterial occlusive disease ": 5.835231522706204, "Asphyxia ": 4.232353464507827, "Bladder cancer ": 2.209249633112308, "Bladder disorder ": 2.28905656664189, "Blood albumin decreased ": 2.9870501055939824, "Blood creatinine increased ": 2.7584972517523774, "Blood disorder ": 2.2341301141439827, "Blood potassium decreased ": 2.4576294536832552, "Blood potassium increased ": 4.283285087509094, "Blood pressure abnormal ": 8.41077458933646, "Blood pressure decreased ": 9.137284867686503, "Blood pressure diastolic decreased ": 11.51735911103616, "Blood pressure diastolic increased ": 6.671122559105506, "Blood pressure fluctuation ": 15.446809599806995, "Blood pressure inadequately controlled ": 77.81979819753562, "Blood pressure increased ": 12.225226551223868, "Blood pressure systolic decreased ": 5.5890487212959865, "Blood pressure systolic increased ": 25.6653199803015, "Blood sodium decreased ": 4.7885294592827, "Blood triglycerides increased ": 2.9673874075255724, "Blood urea increased ": 3.770019833945181, "Blood uric acid increased ": 3.476014068825986, "Brain neoplasm ": 2.382019310003202, "Cardiomegaly ": 2.3604090464674408, "Cerebral disorder ": 2.0859001851400167, "Cerebrovascular accident ": 3.153278703002161, "Choking ": 2.09083577988157, "Cholelithiasis ": 3.0221227854450223, "Concomitant disease aggravated ": 4.455714339930749, "Deafness ": 2.0503002588351293, "Diabetes mellitus ": 6.65583738335543, "Diabetic foot ": 4.855677195260501, "Dysstasia ": 2.0678397476042383, "Erectile dysfunction ": 6.240068436438871, "Expired product administered ": 2.1088754075213507, "Face oedema ": 3.1845933534942628, "Fall ": 2.2621667472018, "Feeling abnormal ": 3.173329836213496, "Fluid retention ": 3.9041960698045415, "General physical condition abnormal ": 4.07628895957286, "Generalised oedema ": 5.260750835741959, "Gingival hypertrophy ": 20.66609785754913, "Gingival swelling ": 5.515886743692176, "Glycosylated haemoglobin increased ": 3.5103486248965994, "Gout ": 3.8660730656265248, "Gynaecomastia ": 3.0080356730993576, "Heart rate decreased ": 2.50237276481534, "Heart rate irregular ": 2.249159403687182, "Hemiplegia ": 3.4331469953837863, "Hyperkalaemia ": 5.860577757065849, "Hyperlipidaemia ": 2.433001099534673, "Hypertension ": 5.7942242588487405, "Hypertensive crisis ": 4.593193105475947, "Hyperuricaemia ": 3.006942678953681, "Hyponatraemia ": 3.413422691656688, "Hypotension ": 3.232621488076054, "Infarction ": 22.452804960152772, "Inflammatory pain ": 12.254302999833044, "Intervertebral disc protrusion ": 3.2890801210137166, "Joint dislocation ": 2.020315567184119, "Joint swelling ": 3.615368351977585, "Localised infection ": 2.5455275806635056, "Lower limb fracture ": 2.221003507566298, "Microalbuminuria ": 10.277324364297993, "Micturition urgency ": 5.286877279446814, "Movement disorder ": 2.1215067836212778, "Neoplasm ": 4.554524020868539, "Nervousness ": 2.931795259301165, "Nocturia ": 4.784199975429818, "Oedema ": 3.399053281214611, "Oedema peripheral ": 11.27238366564034, "Oligohydramnios ": 4.095754414978354, "Orthostatic hypotension ": 2.9332097586002948, "Osteoarthritis ": 2.157010251250268, "Peptic ulcer ": 5.396325214414675, "Peripheral swelling ": 3.1783725195878687, "Physical deconditioning ": 2.4902315446560466, "Pollakiuria ": 3.9922118844832912, "Product colour issue ": 6.306453795668079, "Product packaging issue ": 5.314014646248573, "Product prescribing error ": 4.134033899364286, "Product residue present ": 2.287583403744086, "Raynaud's phenomenon ": 2.516973718853111, "Red blood cell sedimentation rate increased ": 2.223274593071863, "Renal artery stenosis ": 8.552600639720499, "Renal disorder ": 3.3375732780894536, "Sinus node dysfunction ": 4.278199541453614, "Skin cancer ": 2.187589551048494, "Spinal disorder ": 2.7850237261793627, "Swelling face ": 2.593728764268929, "Thyroid cancer ": 2.604958340625363, "Tibia fracture ": 3.923154031353697, "Type 2 diabetes mellitus ": 3.255823184513652, "Ulcer ": 2.2234445772559046, "Upper limb fracture ": 2.4993057898153523, "Vein disorder ": 4.123850184264754, "Ventricular extrasystoles ": 2.04097172482194, "Wrist fracture ": 2.537606806803676, "Wrong technique in product usage process ": 11.309267465121987}
\ No newline at end of file
+{"Hyperkalaemia": 35.17708239849563, "Off label use": 3.240758199715999, "Product use issue": 13.896638095810998, "Sepsis": 14.29925800453056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/452.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/452.json
index 3c07f6981eb..8c810ba5d2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/452.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/452.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.024984914461906, "Abdominal pain ": 2.135090031256191, "Abdominal tenderness ": 4.693681446594666, "Acidosis ": 2.1980557711728936, "Activated partial thromboplastin time prolonged ": 3.5273290095828997, "Acute chest syndrome ": 92.08825314053009, "Acute hepatic failure ": 2.6364694038824537, "Acute leukaemia ": 49.21185453598088, "Acute myeloid leukaemia ": 18.52721990152359, "Acute myeloid leukaemia recurrent ": 3.18253852827501, "Alanine aminotransferase increased ": 6.005797331883106, "Ammonia increased ": 4.95919371310263, "Anuria ": 2.342633833001168, "Aortic stenosis ": 3.64016087415864, "Aplastic anaemia ": 8.908519567182362, "Aspartate aminotransferase increased ": 5.962000952914598, "Atelectasis ": 2.6752595943509974, "Auditory disorder ": 6.109512861854927, "Azotaemia ": 3.514590358387216, "Bacteraemia ": 3.442766723837226, "Bacterial infection ": 2.610407809077524, "Bilirubin conjugated increased ": 8.415419366528496, "Blast cell count increased ": 8.574264750041122, "Blood albumin decreased ": 10.034358852646903, "Blood alkaline phosphatase increased ": 5.117297254549858, "Blood bicarbonate decreased ": 5.665182473005377, "Blood bilirubin increased ": 8.492450775917291, "Blood bilirubin unconjugated increased ": 6.156810747961655, "Blood calcium decreased ": 6.663526877428926, "Blood chloride decreased ": 6.042427153229768, "Blood chloride increased ": 13.48837494653984, "Blood creatine increased ": 2.4061117849041787, "Blood creatinine abnormal ": 5.858515577669999, "Blood creatinine decreased ": 7.373393112307101, "Blood creatinine increased ": 10.89301595912391, "Blood culture positive ": 5.538900191804967, "Blood disorder ": 2.46488971672355, "Blood iron increased ": 119.8258186310886, "Blood lactate dehydrogenase increased ": 4.1037315986560206, "Blood phosphorus decreased ": 5.782874285663376, "Blood potassium decreased ": 2.671426085233832, "Blood potassium increased ": 3.0961584268525693, "Blood pressure diastolic decreased ": 5.634849481211608, "Blood sodium decreased ": 3.4005929509187056, "Blood sodium increased ": 6.069592874776522, "Blood urea decreased ": 5.791122947023763, "Blood urea increased ": 15.412722482895717, "Blood urine present ": 2.799774651437241, "Bone marrow disorder ": 15.083305244680997, "Bone marrow failure ": 4.626901518625361, "Bone marrow transplant ": 109.04897613639268, "Brain natriuretic peptide increased ": 2.286815481654695, "Breath sounds abnormal ": 3.128864064825811, "Carbon dioxide decreased ": 8.212779660713503, "Cardiac failure congestive ": 2.621776447393862, "Cardiac murmur ": 3.606484747885607, "Cardiomegaly ": 2.5713692830985493, "Central venous catheterisation ": 4.467796382445273, "Cholecystectomy ": 4.240231982325946, "Cholecystitis ": 2.362144882383937, "Cholelithiasis ": 4.806846350703177, "Chromaturia ": 4.765211081937268, "Chronic lymphocytic leukaemia ": 5.5681860657286135, "Complications of bone marrow transplant ": 32.829084814980405, "Concomitant disease aggravated ": 2.2500085031681465, "Concomitant disease progression ": 12.400106385308838, "Creatinine renal clearance decreased ": 9.994502285767645, "Deafness ": 4.731883978338439, "Deafness bilateral ": 4.165618786056417, "Deafness neurosensory ": 2.751221742200725, "Deafness unilateral ": 2.863145960057348, "Death ": 10.018908185658946, "Dehydration ": 2.5933876072644275, "Device related infection ": 4.365029135129989, "Dialysis ": 6.654257335853846, "Diarrhoea ": 2.7402876817734425, "Disease progression ": 3.1534446157782527, "Duodenal ulcer ": 5.436534657061409, "Duodenal ulcer haemorrhage ": 3.8422594154079657, "Endotracheal intubation ": 2.641980853039686, "Escherichia infection ": 5.191075715586276, "Faeces discoloured ": 2.8929527530932333, "Failure to thrive ": 2.341738829912798, "Fanconi syndrome ": 8.346222843626329, "Fanconi syndrome acquired ": 10.560227777051518, "Fibrosis ": 2.731191176654721, "Flank pain ": 2.78815378709898, "Full blood count decreased ": 3.914746158348806, "Gastric ulcer ": 4.164796609067894, "Gastritis ": 2.345159660122176, "Gastroenteritis viral ": 2.065526039016758, "Gastrointestinal haemorrhage ": 2.5713179417725045, "Gastrointestinal sounds abnormal ": 2.2892227298083045, "General physical condition abnormal ": 3.273542237884899, "Glomerular filtration rate decreased ": 5.954876076476644, "Glycosuria ": 15.03759326325902, "Graft versus host disease ": 5.228228663555145, "Haematemesis ": 2.00155343878844, "Haematocrit decreased ": 13.433071136717013, "Haemochromatosis ": 47.9677763047148, "Haemoglobin decreased ": 8.302620842972326, "Haemolysis ": 4.469273073500288, "Haemosiderosis ": 93.84489672779354, "Hepatic cirrhosis ": 2.352722657010078, "Hepatic enzyme increased ": 3.1724211683051777, "Hepatic failure ": 4.514250262162161, "Hepatic fibrosis ": 4.473366987393571, "Hepatomegaly ": 4.8437052723761695, "Hip fracture ": 3.2707006407485224, "Hip surgery ": 2.9352915188951987, "Hyperammonaemia ": 2.4277984382224638, "Hyperbilirubinaemia ": 3.5911029552396547, "Hypersplenism ": 16.70671098723399, "Hypertransaminasaemia ": 2.778442021269, "Hypervolaemia ": 3.036101144071559, "Hypoacusis ": 6.995223103479724, "Hypophagia ": 3.079688626183204, "Hypophosphataemia ": 5.706767815221547, "Infection ": 3.6702916949729456, "Iron overload ": 144.148417187257, "Jaundice ": 3.448022727741748, "Leukaemia ": 14.559671672923406, "Leukaemia recurrent ": 4.742938287362217, "Leukocytosis ": 4.307885996779434, "Liver disorder ": 4.537421315914231, "Liver function test abnormal ": 2.604317477218185, "Liver function test increased ": 6.715562055717308, "Lung infiltration ": 4.858509247715617, "Maculopathy ": 4.332810753745315, "Malignant neoplasm progression ": 4.078279143019933, "Marrow hyperplasia ": 13.520492208506973, "Mean cell volume increased ": 9.63950830565918, "Mental status changes ": 3.559153564554105, "Metabolic acidosis ": 4.195162887286397, "Monocyte count increased ": 5.627645872578109, "Mucormycosis ": 5.850057172938651, "Multiple organ dysfunction syndrome ": 2.6130449156549465, "Myelodysplastic syndrome ": 33.35937060389989, "Myelodysplastic syndrome transformation ": 477.023938774888, "Myelofibrosis ": 18.718076744532823, "Neoplasm progression ": 2.3131460758941658, "Nephrolithiasis ": 2.822571011053649, "Neutrophil count increased ": 3.251296950215474, "Occult blood positive ": 4.245833867728391, "Ocular icterus ": 4.793531916887997, "Orthopnoea ": 2.42879212732862, "Pancytopenia ": 2.938076015301399, "Peptic ulcer ": 3.2601980597325584, "Platelet count decreased ": 3.57647195048061, "Platelet count increased ": 4.981653757931294, "Pneumonia ": 2.730508652495221, "Post procedural complication ": 2.508990298476559, "Protein total decreased ": 14.599246450086667, "Protein total increased ": 5.443680301476359, "Protein urine present ": 4.064352527770911, "Proteinuria ": 5.915398565375088, "Pulmonary hypertension ": 2.266171219091458, "Rales ": 2.675232185901105, "Red blood cell count decreased ": 5.257653590865671, "Red cell distribution width increased ": 13.174959563335372, "Renal colic ": 2.2673169375475566, "Renal cyst ": 2.340320063791559, "Renal disorder ": 8.50468473112307, "Renal failure ": 2.904039509973888, "Renal function test abnormal ": 10.870881320319434, "Renal impairment ": 3.516518196953614, "Renal tubular acidosis ": 14.132654913896944, "Renal tubular disorder ": 11.188366386069177, "Renal tubular dysfunction ": 5.08523625607752, "Renal tubular necrosis ": 3.0605772355299328, "Reticulocyte count increased ": 23.22915423843535, "Sepsis ": 4.4121115161537885, "Septic shock ": 2.3982310973700933, "Serum ferritin abnormal ": 172.005066865985, "Serum ferritin decreased ": 19.863293033834637, "Serum ferritin increased ": 199.9848377044482, "Sickle cell anaemia ": 60.007410891245776, "Sickle cell anaemia with crisis ": 1974.8523594569065, "Sickle cell disease ": 295.2599808711, "Spleen disorder ": 7.493857235430455, "Splenectomy ": 15.402495212187567, "Splenomegaly ": 10.18890036612246, "Staphylococcal infection ": 3.2893348568598206, "Stem cell transplant ": 52.6131199819559, "Terminal state ": 8.640217524012392, "Thrombocytosis ": 3.0095814861494827, "Transaminases increased ": 4.696380788409898, "Transfusion reaction ": 17.444916406238743, "Transplant ": 41.05791453028094, "Treatment noncompliance ": 3.1948857889591986, "Ulcer ": 3.0102400110794845, "Urinary tract infection ": 2.1815568398810745, "Urine analysis abnormal ": 3.849751641714897, "Urine output decreased ": 8.527765378255916, "Urine protein/creatinine ratio increased ": 17.29961655292397, "Venoocclusive disease ": 3.823129080982479, "Viral infection ": 2.1822166174237823, "White blood cell count increased ": 6.888005128195317, "Wound infection ": 2.223586435813285}
\ No newline at end of file
+{"Anaphylactic reaction": 2.8118133993395933, "Blood pressure increased": 2.096317476540787, "COVID-19": 10.880656227086767, "COVID-19 pneumonia": 37.67549896918361, "Chest discomfort": 2.550739036516355, "Deep vein thrombosis": 3.1638762042795}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/453.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/453.json
index b1a7a9b5de1..3520720e504 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/453.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/453.json
@@ -1 +1 @@
-{"Blood glucose increased ": 19.75753765638221, "Chest pain ": 3.815785153627956, "Cough ": 5.442992658547183, "Dyspnoea ": 4.677086347492649, "Hyperglycaemia ": 12.53631536929412, "Hypoglycaemia ": 7.456201877066892}
\ No newline at end of file
+{"Feeling abnormal": 20.666757761267096}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/454.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/454.json
index 2c08eae50a5..6799c83db83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/454.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/454.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 12.357646321432814, "Alanine aminotransferase increased ": 5.204419829443654, "Anaemia ": 6.348208513294857, "Ascites ": 38.64683858815975, "Aspartate aminotransferase increased ": 2.1070799263250666, "Asthenia ": 3.371180900629952, "Bilirubin conjugated increased ": 19.84365712763798, "Blood bilirubin increased ": 35.93051297311714, "Cardiac failure ": 2.2370518557048134, "Cardio-respiratory arrest ": 2.293777440128724, "Child-Pugh-Turcotte score increased ": 502.17815484810274, "Cholelithiasis ": 2.8851364449251573, "Chromaturia ": 3.0008808850100834, "Coagulopathy ": 4.279825938909228, "Dyspepsia ": 2.8344906864074657, "Encephalopathy ": 10.850321978614751, "Fibrosis ": 27.12601783360264, "General physical health deterioration ": 2.136884402892667, "Haematemesis ": 2.2427581704836985, "Haemoglobin decreased ": 2.635605868865448, "Haemolysis ": 6.469178084977756, "Hepatic cirrhosis ": 34.06868530255819, "Hepatic cytolysis ": 2.193932514797939, "Hepatic encephalopathy ": 45.286269277756666, "Hepatic failure ": 28.82156358633786, "Hepatic lesion ": 14.322785173136614, "Hepatitis C ": 8.994358041029216, "Hepatocellular carcinoma ": 23.950892692541142, "Hepatorenal syndrome ": 58.33212065210742, "Hyperbilirubinaemia ": 72.20944292212168, "Hyperkalaemia ": 2.613354738259977, "Hypertransaminasaemia ": 9.198437606846044, "Hyponatraemia ": 2.4919166937483785, "International normalised ratio increased ": 2.911021979853384, "Jaundice ": 27.597928530877887, "Leukocytosis ": 4.379126736334502, "Metabolic acidosis ": 2.8869399621863963, "Ocular icterus ": 14.675267961757802, "Oedema ": 2.3626370500136225, "Oedema peripheral ": 3.715158297096089, "Oesophageal varices haemorrhage ": 23.090356520143576, "Portal vein thrombosis ": 18.7773343372558, "Pruritus ": 3.196564920252836, "Renal failure ": 2.0668441056368168, "Splenomegaly ": 5.306851448982666, "Toxic skin eruption ": 3.302812569092926, "Transaminases increased ": 4.711716968982541, "Yellow skin ": 23.521585810174944}
\ No newline at end of file
+{"Aggression": 8.75118043909636, "Agitation": 7.554911944167258, "Atrioventricular block": 14.675575961666516, "Blood pressure decreased": 2.655892552013212, "Bradycardia": 14.38682618061839, "Cognitive disorder": 4.520162761715218, "Confusional state": 3.632108723154914, "Dehydration": 2.183989577082635, "Dementia Alzheimer's type": 47.43302399078536, "Drug interaction": 3.3808627833316325, "Epilepsy": 5.025424609617815, "Fall": 6.732448950192748, "General physical health deterioration": 2.61303145239608, "Hallucination": 9.084379473408289, "Hepatic cytolysis": 5.121763974210132, "Hyponatraemia": 3.1644517546599444, "Hypotension": 2.3221236545970028, "Loss of consciousness": 3.422082898154504, "Memory impairment": 3.766492137692678, "Orthostatic hypotension": 7.952241610648849, "Restlessness": 3.4826921022358106, "Somnolence": 3.20766528912565, "Speech disorder": 3.3351590841194314, "Syncope": 3.3800051315467865, "Urinary incontinence": 7.123450693544794, "Urinary tract infection": 3.859158954182993, "Wrong technique in product usage process": 3.25153303923832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/455.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/455.json
index 0995ed4329f..d4e8dd8fbd3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/455.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/455.json
@@ -1 +1 @@
-{"Abnormal sensation in eye ": 15.953108738421426, "Acute myocardial infarction ": 2.978288707545049, "Age-related macular degeneration ": 97.09030381125112, "Amaurosis ": 24.41685404279485, "Amaurosis fugax ": 45.614817599800816, "Angle closure glaucoma ": 5.0115993190249695, "Anterior chamber cell ": 220.42130832410268, "Anterior chamber disorder ": 257.3020836062199, "Anterior chamber fibrin ": 92.54339094341348, "Anterior chamber flare ": 113.57051882361128, "Anterior chamber inflammation ": 218.07082240954225, "Bacterial endophthalmitis ": 485.90432951033193, "Blepharitis ": 7.002434719385906, "Blindness ": 43.81685030614845, "Blindness transient ": 252.2157695337441, "Blindness unilateral ": 144.42827962924525, "Brain stem infarction ": 9.13342428930855, "Carotid artery stenosis ": 4.320024118545673, "Cataract ": 11.084338251543995, "Cataract operation ": 33.26683624145024, "Cataract subcapsular ": 27.34508598377765, "Cerebellar infarction ": 7.5041412208292195, "Cerebral infarction ": 20.016398461059826, "Cerebrovascular accident ": 4.654098604584848, "Chorioretinitis ": 36.39259936955911, "Choroidal detachment ": 35.59455948346369, "Choroidal neovascularisation ": 137.8067419704543, "Ciliary hyperaemia ": 159.1014628659436, "Conjunctival haemorrhage ": 21.510055283823213, "Conjunctival hyperaemia ": 8.680281110325517, "Conjunctivitis ": 2.224855414779106, "Corneal abrasion ": 79.22424473327833, "Corneal deposits ": 17.64320088758087, "Corneal disorder ": 27.68423639252491, "Corneal epithelium defect ": 29.88706782430245, "Corneal oedema ": 86.31563507370522, "Corneal opacity ": 22.833123397192978, "Cystoid macular oedema ": 22.44112680198683, "Death ": 2.204107918844982, "Dementia ": 2.505447124480729, "Detachment of retinal pigment epithelium ": 372.9459482733552, "Device difficult to use ": 6.087893877864897, "Device use issue ": 217.316309397297, "Diabetic retinal oedema ": 124.92492918291546, "Diabetic retinopathy ": 3.0100254670406428, "Dry age-related macular degeneration ": 122.15658948436617, "Dry eye ": 3.499624143108395, "Dyslalia ": 12.040002848317735, "Endophthalmitis ": 1942.745293787745, "Epiretinal membrane ": 33.33842575754128, "Eye discharge ": 13.289215087438189, "Eye disorder ": 9.147191615736746, "Eye haemorrhage ": 32.4093703467766, "Eye infection ": 39.06543684664333, "Eye infection bacterial ": 129.1118201597616, "Eye infection intraocular ": 87.94672136434488, "Eye infection staphylococcal ": 454.60348197958166, "Eye inflammation ": 254.6131071060545, "Eye injury ": 8.227117728212026, "Eye irritation ": 10.467813731777854, "Eye oedema ": 13.80709139753885, "Eye operation ": 8.098176816648339, "Eye pain ": 28.59637096345653, "Eye swelling ": 3.959579593691514, "Foreign body in eye ": 88.51253366194975, "Foreign body sensation in eyes ": 43.33124274476269, "Glaucoma ": 5.143838253255844, "Haemorrhagic stroke ": 2.5175891256387826, "Hemiparesis ": 2.189787587209978, "Hemiplegia ": 6.7019038531215225, "Hyphaema ": 42.69452236190926, "Hypopyon ": 480.1282698382223, "Hypotony of eye ": 193.76085333873388, "Inadequate aseptic technique in use of product ": 687.0395364038268, "Inappropriate schedule of product administration ": 2.0418929123166327, "Injection site discomfort ": 5.255075021735088, "Injection site haemorrhage ": 4.887088088928733, "Intentional dose omission ": 2.999944850978076, "Intra-ocular injection complication ": 1404.1588835979603, "Intraocular pressure decreased ": 302.121786975536, "Intraocular pressure increased ": 193.96833077091864, "Iridocyclitis ": 79.61471160622825, "Iritis ": 110.45533537298576, "Ischaemic stroke ": 5.0471871161541735, "Keratic precipitates ": 115.21060924115991, "Keratitis ": 11.272315394999668, "Lacrimation increased ": 8.312456745513204, "Lacunar infarction ": 10.415320143467117, "Macular degeneration ": 6.596083476724825, "Macular fibrosis ": 251.2185392333289, "Macular hole ": 133.99738726450923, "Macular oedema ": 43.9068730243313, "Maculopathy ": 14.33417113903644, "Metamorphopsia ": 74.88310403194838, "Multiple use of single-use product ": 391.0920808504305, "Myocardial infarction ": 2.8229705505699805, "Neovascular age-related macular degeneration ": 129.7050682507325, "Non-infectious endophthalmitis ": 5223.992318143326, "Ocular discomfort ": 11.369010583106714, "Ocular hyperaemia ": 16.473275989170876, "Ocular hypertension ": 86.21309615490061, "Ocular procedural complication ": 610.6207487368232, "Ocular vasculitis ": 90.79550693576324, "Photophobia ": 6.238307229204585, "Photopsia ": 9.575116758061895, "Polypoidal choroidal vasculopathy ": 1001.2685046105308, "Posterior capsule opacification ": 67.87894724426535, "Product contamination ": 11.976672147455483, "Product dose omission issue ": 2.623112914533888, "Product prescribing issue ": 3.486657940211172, "Pseudoendophthalmitis ": 1820.0005019124112, "Refusal of treatment by patient ": 13.90272595391154, "Retinal artery occlusion ": 93.34376209234352, "Retinal degeneration ": 65.44171815933119, "Retinal detachment ": 26.495385864554127, "Retinal disorder ": 15.356751614827449, "Retinal exudates ": 24.19964606286488, "Retinal haemorrhage ": 76.53477427877937, "Retinal ischaemia ": 23.23073394851843, "Retinal neovascularisation ": 130.09748721286016, "Retinal oedema ": 120.55891837390185, "Retinal pigment epithelial tear ": 2407.272277697576, "Retinal pigment epitheliopathy ": 57.26161976336248, "Retinal scar ": 140.04274260126832, "Retinal tear ": 36.77799147822549, "Retinal thickening ": 334.74645262170145, "Retinal vascular disorder ": 29.07732837897866, "Retinal vascular occlusion ": 25.03470553304416, "Retinal vasculitis ": 39.34633060336998, "Retinal vein occlusion ": 13.165534798078466, "Scleritis ": 14.617897733175546, "Serous retinal detachment ": 44.76182689470113, "Staphylococcus test positive ": 13.1720995027904, "Streptococcal infection ": 7.1067944322582095, "Subretinal fluid ": 264.2845267900933, "Sudden visual loss ": 60.4421654417824, "Suspected product quality issue ": 19.89185554968532, "Swelling of eyelid ": 4.114859367495336, "Syringe issue ": 28.849546223776585, "Therapeutic product ineffective ": 4.799985466043739, "Thrombotic cerebral infarction ": 36.69699436613178, "Toxic anterior segment syndrome ": 29.81871117223606, "Transient ischaemic attack ": 7.290471782483634, "Ulcerative keratitis ": 7.643840467955442, "Uveitis ": 98.5074723354702, "Vision blurred ": 12.0628530028303, "Visual acuity reduced ": 106.82419652228845, "Visual acuity reduced transiently ": 205.06829786600085, "Visual field defect ": 9.664499307605578, "Visual impairment ": 15.071782429343443, "Vitreal cells ": 605.7617790476562, "Vitrectomy ": 2302.320212729981, "Vitreous detachment ": 28.306901436128783, "Vitreous disorder ": 187.1509105713562, "Vitreous floaters ": 98.6555427228078, "Vitreous haemorrhage ": 104.27708349515328, "Vitreous opacities ": 296.5778188337842, "Vitritis ": 341.3858393719946, "Wrong technique in product usage process ": 6.9293358692259455}
\ No newline at end of file
+{"Acute kidney injury": 9.28166861438496, "Decreased appetite": 3.43964183359626, "Weight decreased": 5.429548847765617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/456.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/456.json
index 1be8c42352e..609292ad34b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/456.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/456.json
@@ -1 +1 @@
-{"Confusional state ": 4.7280342313327886}
\ No newline at end of file
+{"Acute kidney injury": 2.3754092024919373, "Angina pectoris": 2.862233653237765, "Angioedema": 2.980556821838915, "Anuria": 2.5336996573190254, "Aortic aneurysm": 6.873072114304232, "Aortic arteriosclerosis": 5.060357905848247, "Aortic valve incompetence": 4.628532070591958, "Arrhythmia": 3.1963046096998564, "Arterial occlusive disease": 5.835231522706204, "Asphyxia": 4.232353464507827, "Bladder cancer": 2.209249633112308, "Bladder disorder": 2.28905656664189, "Blood albumin decreased": 2.9870501055939824, "Blood creatinine increased": 2.7584972517523774, "Blood disorder": 2.2341301141439827, "Blood potassium decreased": 2.4576294536832552, "Blood potassium increased": 4.283285087509094, "Blood pressure abnormal": 8.41077458933646, "Blood pressure decreased": 9.136985257030668, "Blood pressure diastolic decreased": 11.51735911103616, "Blood pressure diastolic increased": 6.671122559105506, "Blood pressure fluctuation": 15.446809599806995, "Blood pressure inadequately controlled": 77.81979819753562, "Blood pressure increased": 12.225009025269896, "Blood pressure systolic decreased": 5.5890487212959865, "Blood pressure systolic increased": 25.6653199803015, "Blood sodium decreased": 4.7885294592827, "Blood triglycerides increased": 2.9673874075255724, "Blood urea increased": 3.770019833945181, "Blood uric acid increased": 3.476014068825986, "Brain neoplasm": 2.382019310003202, "Cardiomegaly": 2.3604090464674408, "Cerebral disorder": 2.0859001851400167, "Cerebrovascular accident": 3.1532216812759257, "Choking": 2.09083577988157, "Cholelithiasis": 3.0221227854450223, "Concomitant disease aggravated": 4.455714339930749, "Deafness": 2.0503002588351293, "Diabetes mellitus": 6.65583738335543, "Diabetic foot": 4.855677195260501, "Dysstasia": 2.0673682986739044, "Erectile dysfunction": 6.240068436438871, "Expired product administered": 2.1088754075213507, "Face oedema": 3.1845933534942628, "Fall": 2.262108614493614, "Feeling abnormal": 3.173268542119452, "Fluid retention": 3.9041960698045415, "General physical condition abnormal": 4.07628895957286, "Generalised oedema": 5.260750835741959, "Gingival hypertrophy": 20.66609785754913, "Gingival swelling": 5.515886743692176, "Glycosylated haemoglobin increased": 3.5103486248965994, "Gout": 3.8660730656265248, "Gynaecomastia": 3.0080356730993576, "Heart rate decreased": 2.50237276481534, "Heart rate irregular": 2.249159403687182, "Hemiplegia": 3.4331469953837863, "Hyperkalaemia": 5.859764448611648, "Hyperlipidaemia": 2.433001099534673, "Hypertension": 5.79416405383167, "Hypertensive crisis": 4.593193105475947, "Hyperuricaemia": 3.006942678953681, "Hyponatraemia": 3.413422691656688, "Hypotension": 3.232546487219926, "Infarction": 22.452804960152772, "Inflammatory pain": 12.254302999833044, "Intervertebral disc protrusion": 3.2890801210137166, "Joint dislocation": 2.020315567184119, "Joint swelling": 3.615368351977585, "Localised infection": 2.5455275806635056, "Lower limb fracture": 2.221003507566298, "Microalbuminuria": 10.277324364297993, "Micturition urgency": 5.286877279446814, "Movement disorder": 2.1215067836212778, "Neoplasm": 4.554524020868539, "Nervousness": 2.931795259301165, "Nocturia": 4.784199975429818, "Oedema": 3.399053281214611, "Oedema peripheral": 11.272101538207338, "Oligohydramnios": 4.095754414978354, "Orthostatic hypotension": 2.9325765279722686, "Osteoarthritis": 2.157010251250268, "Peptic ulcer": 5.396325214414675, "Peripheral swelling": 3.1783725195878687, "Physical deconditioning": 2.4902315446560466, "Pollakiuria": 3.9922118844832912, "Product colour issue": 6.306453795668079, "Product packaging issue": 5.314014646248573, "Product prescribing error": 4.134033899364286, "Product residue present": 2.287583403744086, "Raynaud's phenomenon": 2.516973718853111, "Red blood cell sedimentation rate increased": 2.223274593071863, "Renal artery stenosis": 8.552600639720499, "Renal disorder": 3.3370791827434383, "Sinus node dysfunction": 4.278199541453614, "Skin cancer": 2.187589551048494, "Spinal disorder": 2.7850237261793627, "Swelling face": 2.593728764268929, "Thyroid cancer": 2.604958340625363, "Tibia fracture": 3.923154031353697, "Type 2 diabetes mellitus": 3.255823184513652, "Ulcer": 2.2234445772559046, "Upper limb fracture": 2.4993057898153523, "Vein disorder": 4.123850184264754, "Ventricular extrasystoles": 2.04097172482194, "Wrist fracture": 2.537606806803676, "Wrong technique in product usage process": 11.309267465121987}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/457.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/457.json
index 3d3e0dad443..878d19dc2a7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/457.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/457.json
@@ -1 +1 @@
-{"Balance disorder ": 17.061613810611448, "Condition aggravated ": 2.717601902745883, "Constipation ": 2.2648720019344477, "Dysstasia ": 7.656753256853584, "Encephalopathy ": 6.542838570896499, "Excessive granulation tissue ": 811.0982281260475, "Fall ": 7.769170378106752, "Gait disturbance ": 14.216737476896416, "Gait inability ": 5.978552544820518, "Generalised tonic-clonic seizure ": 11.65399367869762, "Loss of consciousness ": 2.000328761207167, "Loss of personal independence in daily activities ": 3.0102149107026435, "Medical device site discharge ": 4436.643070289055, "Medical device site erosion ": 2704.271097350109, "Medical device site infection ": 944.4046531340248, "Mobility decreased ": 6.415137612286107, "Multiple sclerosis ": 34.75634760554862, "Multiple sclerosis relapse ": 18.416880905597733, "Muscular weakness ": 5.029474515911486, "Musculoskeletal stiffness ": 2.989313744667246, "Neurotoxicity ": 15.890887142486475, "Pollakiuria ": 5.931940916156075, "Product substitution issue ": 60.77426743591488, "Seizure ": 2.232063742664674, "Staphylococcal infection ": 17.74879486115874, "Status epilepticus ": 12.605258572806523, "Therapy cessation ": 37.72586113632104, "Tremor ": 2.1573519936605483, "Urinary tract infection ": 3.3210228222224587, "Wound dehiscence ": 210.17914583594228}
\ No newline at end of file
+{"Abdominal distension": 2.024984914461906, "Abdominal pain": 2.135090031256191, "Abdominal tenderness": 4.693681446594666, "Acidosis": 2.1980557711728936, "Activated partial thromboplastin time prolonged": 3.5273290095828997, "Acute chest syndrome": 92.08825314053009, "Acute hepatic failure": 2.6364694038824537, "Acute leukaemia": 49.21185453598088, "Acute myeloid leukaemia": 18.52721990152359, "Acute myeloid leukaemia recurrent": 3.18253852827501, "Alanine aminotransferase increased": 6.005797331883106, "Ammonia increased": 4.95919371310263, "Anuria": 2.342633833001168, "Aortic stenosis": 3.64016087415864, "Aplastic anaemia": 8.908519567182362, "Aspartate aminotransferase increased": 5.962000952914598, "Atelectasis": 2.6752595943509974, "Auditory disorder": 6.109512861854927, "Azotaemia": 3.514590358387216, "Bacteraemia": 3.442766723837226, "Bacterial infection": 2.610407809077524, "Bilirubin conjugated increased": 8.415419366528496, "Blast cell count increased": 8.574264750041122, "Blood albumin decreased": 10.034358852646903, "Blood alkaline phosphatase increased": 5.117297254549858, "Blood bicarbonate decreased": 5.665182473005377, "Blood bilirubin increased": 8.492450775917291, "Blood bilirubin unconjugated increased": 6.156810747961655, "Blood calcium decreased": 6.663526877428926, "Blood chloride decreased": 6.042427153229768, "Blood chloride increased": 13.48837494653984, "Blood creatine increased": 2.4061117849041787, "Blood creatinine abnormal": 5.858515577669999, "Blood creatinine decreased": 7.373393112307101, "Blood creatinine increased": 10.89301595912391, "Blood culture positive": 5.538900191804967, "Blood disorder": 2.46488971672355, "Blood iron increased": 119.8258186310886, "Blood lactate dehydrogenase increased": 4.1037315986560206, "Blood phosphorus decreased": 5.782874285663376, "Blood potassium decreased": 2.671426085233832, "Blood potassium increased": 3.0961584268525693, "Blood pressure diastolic decreased": 5.634849481211608, "Blood sodium decreased": 3.4005929509187056, "Blood sodium increased": 6.069592874776522, "Blood urea decreased": 5.791122947023763, "Blood urea increased": 15.412722482895717, "Blood urine present": 2.799774651437241, "Bone marrow disorder": 15.083305244680997, "Bone marrow failure": 4.626901518625361, "Bone marrow transplant": 109.04897613639268, "Brain natriuretic peptide increased": 2.286815481654695, "Breath sounds abnormal": 3.128864064825811, "Carbon dioxide decreased": 8.212779660713503, "Cardiac failure congestive": 2.6215772239053603, "Cardiac murmur": 3.606484747885607, "Cardiomegaly": 2.5713692830985493, "Central venous catheterisation": 4.467796382445273, "Cholecystectomy": 4.240231982325946, "Cholecystitis": 2.362144882383937, "Cholelithiasis": 4.806846350703177, "Chromaturia": 4.765211081937268, "Chronic lymphocytic leukaemia": 5.563484214017677, "Complications of bone marrow transplant": 32.829084814980405, "Concomitant disease aggravated": 2.2500085031681465, "Concomitant disease 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"Gastroenteritis viral": 2.065526039016758, "Gastrointestinal haemorrhage": 2.5713179417725045, "Gastrointestinal sounds abnormal": 2.2892227298083045, "General physical condition abnormal": 3.273542237884899, "Glomerular filtration rate decreased": 5.954876076476644, "Glycosuria": 15.03759326325902, "Graft versus host disease": 5.228228663555145, "Haematemesis": 2.0013752884498905, "Haematocrit decreased": 13.433071136717013, "Haemochromatosis": 47.9677763047148, "Haemoglobin decreased": 8.302620842972326, "Haemolysis": 4.469273073500288, "Haemosiderosis": 93.84489672779354, "Hepatic cirrhosis": 2.352722657010078, "Hepatic enzyme increased": 3.1724211683051777, "Hepatic failure": 4.514250262162161, "Hepatic fibrosis": 4.473366987393571, "Hepatomegaly": 4.8437052723761695, "Hip fracture": 3.2707006407485224, "Hip surgery": 2.9352915188951987, "Hyperammonaemia": 2.4277984382224638, "Hyperbilirubinaemia": 3.5911029552396547, "Hypersplenism": 16.70671098723399, "Hypertransaminasaemia": 2.778442021269, "Hypervolaemia": 3.036101144071559, "Hypoacusis": 6.994626796362686, "Hypophagia": 3.079688626183204, "Hypophosphataemia": 5.706767815221547, "Infection": 3.6702916949729456, "Iron overload": 144.148417187257, "Jaundice": 3.448022727741748, "Leukaemia": 14.559671672923406, "Leukaemia recurrent": 4.742938287362217, "Leukocytosis": 4.307885996779434, "Liver disorder": 4.537421315914231, "Liver function test abnormal": 2.604317477218185, "Liver function test increased": 6.715562055717308, "Lung infiltration": 4.858509247715617, "Maculopathy": 4.332810753745315, "Malignant neoplasm progression": 4.078279143019933, "Marrow hyperplasia": 13.520492208506973, "Mean cell volume increased": 9.63950830565918, "Mental status changes": 3.559153564554105, "Metabolic acidosis": 4.195162887286397, "Monocyte count increased": 5.627645872578109, "Mucormycosis": 5.850057172938651, "Multiple organ dysfunction syndrome": 2.6130449156549465, "Myelodysplastic syndrome": 33.35937060389989, "Myelodysplastic syndrome transformation": 477.023938774888, "Myelofibrosis": 18.718076744532823, "Neoplasm progression": 2.3131460758941658, "Nephrolithiasis": 2.822102014578238, "Neutrophil count increased": 3.251296950215474, "Occult blood positive": 4.245833867728391, "Ocular icterus": 4.793531916887997, "Orthopnoea": 2.42879212732862, "Pancytopenia": 2.938076015301399, "Peptic ulcer": 3.2601980597325584, "Platelet count decreased": 3.57647195048061, "Platelet count increased": 4.981653757931294, "Pneumonia": 2.730508652495221, "Post procedural complication": 2.508990298476559, "Protein total decreased": 14.599246450086667, "Protein total increased": 5.443680301476359, "Protein urine present": 4.064352527770911, "Proteinuria": 5.915398565375088, "Pulmonary hypertension": 2.266171219091458, "Rales": 2.675232185901105, "Red blood cell count decreased": 5.257653590865671, "Red cell distribution width increased": 13.174959563335372, "Renal colic": 2.2673169375475566, "Renal cyst": 2.340320063791559, "Renal disorder": 8.503410049026455, "Renal failure": 2.904039509973888, "Renal function test abnormal": 10.870881320319434, "Renal impairment": 3.516518196953614, "Renal tubular acidosis": 14.132654913896944, "Renal tubular disorder": 11.188366386069177, "Renal tubular dysfunction": 5.08523625607752, "Renal tubular necrosis": 3.0605772355299328, "Reticulocyte count increased": 23.22915423843535, "Sepsis": 4.4121115161537885, "Septic shock": 2.3982310973700933, "Serum ferritin abnormal": 172.005066865985, "Serum ferritin decreased": 19.863293033834637, "Serum ferritin increased": 199.9848377044482, "Sickle cell anaemia": 60.007410891245776, "Sickle cell anaemia with crisis": 1974.8523594569065, "Sickle cell disease": 295.2599808711, "Spleen disorder": 7.493857235430455, "Splenectomy": 15.402495212187567, "Splenomegaly": 10.18890036612246, "Staphylococcal infection": 3.2893348568598206, "Stem cell transplant": 52.6131199819559, "Terminal state": 8.640217524012392, "Thrombocytosis": 3.0095814861494827, "Transaminases increased": 4.696090664151646, "Transfusion reaction": 17.444916406238743, "Transplant": 41.05791453028094, "Treatment noncompliance": 3.1948857889591986, "Ulcer": 3.0102400110794845, "Urinary tract infection": 2.1815568398810745, "Urine analysis abnormal": 3.849751641714897, "Urine output decreased": 8.527765378255916, "Urine protein/creatinine ratio increased": 17.29961655292397, "Venoocclusive disease": 3.823129080982479, "Viral infection": 2.1822166174237823, "White blood cell count increased": 6.8866689573615645, "Wound infection": 2.223586435813285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/458.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/458.json
index 735abae9f46..a95f1d21e98 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/458.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/458.json
@@ -1 +1 @@
-{"Accident ": 10.083547691487958, "Acute disseminated encephalomyelitis ": 14.206156265711956, "Ankle fracture ": 5.198550466919186, "Ataxia ": 2.7133848378113123, "Balance disorder ": 11.360944307690714, "Bladder disorder ": 23.549927721857088, "Blood iron decreased ": 4.1191062719808205, "Blood test abnormal ": 5.662800251634595, "Brain neoplasm ": 3.674237714579912, "Caesarean section ": 3.2125760278947717, "Central nervous system lesion ": 8.34742246284733, "Constipation ": 2.367453132382024, "Coronavirus infection ": 23.26906898061623, "Cystitis ": 17.701344104971934, "Cystitis noninfective ": 29.185509481656677, "Dermatomyositis ": 8.371358691311203, "Dizziness ": 2.0183628388931005, "Drug ineffective ": 2.484481333663405, "Dysgraphia ": 4.572940615291889, "Dysstasia ": 7.538650716393929, "Electric shock sensation ": 2.327878863103464, "Epilepsy ": 7.162933786473334, "Euphoric mood ": 4.0864507977874, "Extra dose administered ": 3.8930002781424022, "Facial pain ": 6.99874061094816, "Fall ": 5.396760153755461, "Feeling abnormal ": 2.1518066792860533, "Feeling of despair ": 5.1822022962809, "Fine motor skill dysfunction ": 10.192195556798971, "Gait disturbance ": 15.309001813817172, "Gait inability ": 11.167613368151832, "Gastrointestinal disorder ": 3.2073882133521487, "Gastrointestinal pain ": 2.088580169190032, "General physical health deterioration ": 2.67008638100557, "General symptom ": 11.966220429530866, "Generalised tonic-clonic seizure ": 4.798644996758488, "Head injury ": 2.184920308143882, "Hemiparesis ": 2.259897341654898, "Hip fracture ": 6.35517437997437, "Hypertonic bladder ": 12.448125500454152, "Incontinence ": 4.922101222891159, "Inflammatory marker increased ": 5.808849382764881, "Initial insomnia ": 2.773036240892231, "Insomnia ": 4.463119712970041, "Intentional dose omission ": 4.250524260957696, "Intentional product misuse ": 3.242388889528468, "Intentional underdose ": 17.65374674703969, "Intervertebral disc protrusion ": 3.760405865652095, "Invasive ductal breast carcinoma ": 7.691554059921631, "Joint injury ": 2.018341606893371, "Kidney infection ": 2.202146993378619, "Ligament sprain ": 8.958605722647864, "Liver function test increased ": 2.212883192758298, "Loss of control of legs ": 43.23925065677231, "Loss of therapeutic response ": 27.01715793645097, "Lower limb fracture ": 4.551707006065149, "Lymphocyte count decreased ": 8.259070522120584, "Lymphopenia ": 8.924382360284124, "Magnetic resonance imaging abnormal ": 14.742149006259872, "Mental disorder ": 3.166893017963858, "Micturition urgency ": 4.095215788715235, "Mobility decreased ": 13.288268779791428, "Motor dysfunction ": 29.0962909989145, "Multiple sclerosis ": 55.70703471685937, "Multiple sclerosis relapse ": 65.08492093100487, "Muscle atrophy ": 2.6597416190518715, "Muscle fatigue ": 2.505136799032439, "Muscle spasms ": 3.2363984014509555, "Muscle spasticity ": 32.28110392569897, "Muscle tightness ": 6.347879849822971, "Muscular weakness ": 3.7779090083358593, "Musculoskeletal disorder ": 23.05037899143051, "Nasopharyngitis ": 3.1290200671903023, "Nephrolithiasis ": 3.179608486618043, "Neuralgia ": 2.807592063739979, "Paraparesis ": 8.25838688906546, "Partial seizures ": 3.046019093501283, "Peroneal nerve palsy ": 8.648097353368252, "Poor quality sleep ": 15.788647883684892, "Prescribed underdose ": 17.568032037353976, "Primary progressive multiple sclerosis ": 614.9804246750336, "Product dose omission in error ": 35.238367265280324, "Product dose omission issue ": 6.633815060503122, "Product residue present ": 9.363383061255892, "Progressive multifocal leukoencephalopathy ": 6.029842328011755, "Progressive multiple sclerosis ": 152.731634913918, "Restless legs syndrome ": 3.876156547255435, "Secondary progressive multiple sclerosis ": 421.7103540247612, "Seizure ": 2.5709142900923694, "Sensory disturbance ": 3.2550162012007764, "Sleep disorder ": 3.9772654213152334, "Speech disorder ": 2.40039028875961, "Status epilepticus ": 9.810355066610304, "Stem cell transplant ": 33.73663761805472, "Stress ": 2.04133006887499, "Temperature intolerance ": 12.010170508311834, "Terminal state ": 6.328342557353514, "Therapeutic product effect decreased ": 5.32948275007929, "Therapeutic response shortened ": 10.486372404460942, "Therapy non-responder ": 17.983094097257837, "Toothache ": 2.762628034169202, "Trigeminal neuralgia ": 31.571853172319333, "Uhthoff's phenomenon ": 199.91001590493025, "Underdose ": 27.43747550550359, "Upper limb fracture ": 3.574884307683732, "Urinary incontinence ": 4.406174247849132, "Urinary tract disorder ": 6.585026351261908, "Urinary tract infection ": 8.871595510774332, "Urinary tract obstruction ": 31.152876266958145, "Urosepsis ": 4.778086687125195, "Vertigo ": 2.115792545516801, "Vitamin D deficiency ": 5.138622143529631}
\ No newline at end of file
+{"Blood glucose increased": 19.75753765638221, "Chest pain": 3.815785153627956, "Cough": 5.442942176737209, "Dyspnoea": 4.677016863381564, "Hyperglycaemia": 12.53631536929412, "Hypoglycaemia": 7.455950214066011}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/459.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/459.json
index 96d2a4b8b77..870ca5b0f51 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/459.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/459.json
@@ -1 +1 @@
-{"Acute respiratory failure ": 3.228040037309573, "Adrenal insufficiency ": 2.9001564677388982, "Anaphylactic reaction ": 4.69688118111868, "Appetite disorder ": 5.732178515833106, "Asthma ": 27.19732619552656, "Asthmatic crisis ": 17.05462748923231, "Blood immunoglobulin E increased ": 8.6905144511659, "Body height decreased ": 3.040878250516859, "Breast cancer female ": 7.11922868458, "Bronchial secretion retention ": 11.6796909652904, "Bronchiectasis ": 3.1338368606986813, "Bronchitis ": 3.236094928854714, "Bronchopulmonary aspergillosis ": 2.8358618755173035, "Bronchospasm ": 2.579408739712399, "COVID-19 pneumonia ": 2.7191144290205216, "Chest discomfort ": 2.2992454139522245, "Chronic obstructive pulmonary disease ": 2.562956076023725, "Cough ": 2.590465080581568, "Decreased activity ": 3.4317578075328647, "Device defective ": 18.528252573360245, "Device delivery system issue ": 21.61153615012997, "Device issue ": 4.170066217293395, "Device leakage ": 45.11851250063003, "Device malfunction ": 4.349305004311753, "Device use issue ": 28.55691187999221, "Drug dose omission by device ": 40.254897162202646, "Drug effect less than expected ": 13.273678429179885, "Dysphonia ": 3.427029109676699, "Dyspnoea ": 2.5345130508241764, "Ectopic pregnancy ": 10.090777460545578, "Eczema ": 2.596636665497345, "Eosinophil count abnormal ": 88.22478485582131, "Eosinophil count decreased ": 14.512679392957857, "Eosinophil count increased ": 46.630476579515296, "Eosinophilia ": 2.9617839800750385, "Eosinophilic granulomatosis with polyangiitis ": 38.27959933131371, "Eye disorder ": 2.434512807499739, "Forced expiratory volume decreased ": 14.035157058805105, "Frustration tolerance decreased ": 3.493919857149636, "Generalised oedema ": 2.1089210727636485, "Hypersensitivity ": 2.3942412351956426, "Illness ": 2.3052761084296542, "Immune system disorder ": 2.3549444258227687, "Inability to afford medication ": 15.378595623875018, "Inappropriate schedule of product administration ": 4.257741415837461, "Incorrect dose administered by device ": 14.852070981448565, "Injection site haemorrhage ": 3.484462650716836, "Injection site rash ": 4.209514037073743, "Insurance issue ": 27.6214310630625, "Lower respiratory tract infection ": 3.326421035960379, "Lung disorder ": 4.149015452965188, "Middle insomnia ": 4.018446164159955, "Multiple allergies ": 5.335703318262164, "Nasal congestion ": 3.5571198197191483, "Nasal polyps ": 49.50810648472746, "Nasopharyngitis ": 2.591100415508424, "Needle issue ": 6.533851924653591, "Obstructive airways disorder ": 3.967576993899162, "Organising pneumonia ": 4.02091734505425, "Oropharyngeal discomfort ": 2.621140735800155, "Oxygen saturation decreased ": 3.1457537149250325, "Pharyngitis ": 7.445291485187445, "Pneumonia ": 2.221811881966053, "Pneumonia bacterial ": 3.6744238650331686, "Polyneuropathy ": 2.126801695656414, "Product distribution issue ": 43.56567503761844, "Product dose omission issue ": 7.395340617177716, "Productive cough ": 4.283133141130589, "Pulmonary function test decreased ": 21.748748197553148, "Pulmonary mass ": 2.1948267348719708, "Pulmonary nocardiosis ": 152.91542792823836, "Pulmonary pain ": 3.2093941570550384, "Pustule ": 2.3954926159662078, "Rash pruritic ": 2.409210588587377, "Respiratory disorder ": 2.146611505602336, "Respiratory tract congestion ": 2.9221683638015103, "Rheumatic disorder ": 4.9959519892270565, "Rhinitis ": 4.311639311834452, "SARS-CoV-2 test negative ": 13.338254109417225, "Seasonal allergy ": 2.3333526677452032, "Secretion discharge ": 8.840548957168602, "Serum sickness ": 11.955447439779324, "Sinus disorder ": 3.828070718963246, "Sinusitis ": 2.948986213664691, "Skin plaque ": 2.3104415971961494, "Skin reaction ": 2.451679171130251, "Sleep disorder due to a general medical condition ": 2.431636024798509, "Symptom recurrence ": 18.220197870284245, "Therapeutic product effect decreased ": 2.2401234419993195, "Therapeutic response shortened ": 12.355770217074172, "Throat tightness ": 3.053162379418976, "Urticaria ": 2.979043332122493, "Viral infection ": 3.739458991447773, "Wheezing ": 7.998850976150823, "Wrong technique in device usage process ": 14.498826930334516}
\ No newline at end of file
+{"Acute hepatic failure": 12.357646321432814, "Alanine aminotransferase increased": 5.204419829443654, "Anaemia": 6.348208513294857, "Ascites": 38.64683858815975, "Aspartate aminotransferase increased": 2.1070799263250666, "Asthenia": 3.3710467053437125, "Bilirubin conjugated increased": 19.84365712763798, "Blood bilirubin increased": 35.93051297311714, "Cardiac failure": 2.236847596079763, "Cardio-respiratory arrest": 2.293777440128724, "Child-Pugh-Turcotte score increased": 502.17815484810274, "Cholelithiasis": 2.8851364449251573, "Chromaturia": 3.0008808850100834, "Coagulopathy": 4.279825938909228, "Dyspepsia": 2.8344906864074657, "Encephalopathy": 10.850321978614751, "Fibrosis": 27.12601783360264, "General physical health deterioration": 2.136884402892667, "Haematemesis": 2.2425592430465566, "Haemoglobin decreased": 2.635605868865448, "Haemolysis": 6.469178084977756, "Hepatic cirrhosis": 34.06868530255819, "Hepatic cytolysis": 2.193932514797939, "Hepatic encephalopathy": 45.286269277756666, "Hepatic failure": 28.82156358633786, "Hepatic lesion": 14.322785173136614, "Hepatitis C": 8.994358041029216, "Hepatocellular carcinoma": 23.950892692541142, "Hepatorenal syndrome": 58.33212065210742, "Hyperbilirubinaemia": 72.20944292212168, "Hyperkalaemia": 2.6129943169225185, "Hypertransaminasaemia": 9.198437606846044, "Hyponatraemia": 2.4919166937483785, "International normalised ratio increased": 2.911021979853384, "Jaundice": 27.597928530877887, "Leukocytosis": 4.379126736334502, "Metabolic acidosis": 2.8869399621863963, "Ocular icterus": 14.675267961757802, "Oedema": 2.3626370500136225, "Oedema peripheral": 3.7150664169074985, "Oesophageal varices haemorrhage": 23.090356520143576, "Portal vein thrombosis": 18.7773343372558, "Pruritus": 3.1965261745060336, "Renal failure": 2.0668441056368168, "Splenomegaly": 5.306851448982666, "Toxic skin eruption": 3.302812569092926, "Transaminases increased": 4.711428191841454, "Yellow skin": 23.521585810174944}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/46.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/46.json
index 9d86e0e7fad..098aa837285 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/46.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/46.json
@@ -1 +1 @@
-{"Disease progression ": 15.656924415897135, "Drug resistance ": 24.285949596603377, "Malignant neoplasm progression ": 15.509173382992389, "Maternal exposure during pregnancy ": 9.569216513522722, "Metastases to central nervous system ": 68.3430419709596, "Neoplasm progression ": 20.35142371057902}
\ No newline at end of file
+{"Constipation": 8.640128677945562, "Drug interaction": 5.997742681229084, "Interstitial lung disease": 19.73846127964552}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/460.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/460.json
index 920a276288e..90c1cf4577b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/460.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/460.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 2.5503264582655567, "Alopecia ": 2.8396993823035825, "Aphthous ulcer ": 2.233888037302952, "Ascites ": 3.364705001114162, "Back pain ": 2.482875367776743, "Blood oestrogen increased ": 18.73559942213892, "Body height decreased ": 12.636934433116048, "Bone cancer ": 14.068348745220472, "Bone cancer metastatic ": 49.590901015877954, "Bone lesion ": 18.20985051590945, "Bone pain ": 5.574556169677578, "Breast cancer ": 4.948846560443956, "Breast cancer female ": 16.866753453846005, "Breast cancer metastatic ": 27.585140602878425, "Breast cancer recurrent ": 94.15095590242464, "Breast cancer stage IV ": 72.81054938735434, "Breast mass ": 3.742652053496448, "Bronchiectasis ": 2.558023310148499, "Bundle branch block left ": 2.129040578776831, "Cancer pain ": 14.88551221002136, "Carbohydrate antigen 15-3 increased ": 67.4891485083566, "Carcinoembryonic antigen increased ": 6.597636099990874, "Carpal tunnel syndrome ": 2.225862990347349, "Circumstance or information capable of leading to medication error ": 2.3056823181092714, "Constipation ": 2.239601036729225, "Cough ": 2.550555425057144, "Cytopenia ": 2.9905385837558547, "Decubitus ulcer ": 2.160165154920504, "Disease progression ": 5.958503723683507, "Dry skin ": 3.128967825685466, "Dysstasia ": 2.1005444086792786, "Embolism ": 2.977496106906006, "Femur fracture ": 2.961305766318348, "Full blood count abnormal ": 4.858722266135065, "Full blood count decreased ": 6.017903672628327, "Gait disturbance ": 2.2563659897000767, "Haemoglobin decreased ": 2.4165839570644683, "Hair growth abnormal ": 2.4907961937178054, "Hepatic enzyme abnormal ": 2.501084647093605, "Hepatic failure ": 3.258113086575281, "Hepatic lesion ": 8.233547579008386, "Hepatic neoplasm ": 12.644570116089673, "Hip fracture ": 2.180316259294209, "Hot flush ": 5.2277386044018685, "Hydrocephalus ": 2.254379717153779, "Hydronephrosis ": 2.7969844117775, "Hypercalcaemia ": 2.2689823800182225, "Induration ": 5.237852693408737, "Injection site abscess ": 5.593973629299978, "Injection site bruising ": 4.192591382421722, "Injection site cellulitis ": 11.169839919279951, "Injection site cyst ": 71.52175056452691, "Injection site discomfort ": 7.944307935574326, "Injection site extravasation ": 4.766539149111688, "Injection site haematoma ": 2.8064359679209283, "Injection site haemorrhage ": 2.969183728394444, "Injection site hypersensitivity ": 4.180749293829014, "Injection site hypoaesthesia ": 7.182856981274203, "Injection site induration ": 7.820753304027004, "Injection site infection ": 9.30952730204975, "Injection site injury ": 23.0214824752152, "Injection site irritation ": 8.658463093599607, "Injection site mass ": 19.188252903653304, "Injection site necrosis ": 26.26696720560008, "Injection site nodule ": 20.34957456649347, "Injection site pain ": 2.018119328083768, "Injection site pruritus ": 2.5175854666802238, "Injection site rash ": 3.835060711551751, "Injection site ulcer ": 62.73676458803966, "Injection site urticaria ": 2.048212424913828, "Injection site vesicles ": 5.03903485224662, "Interstitial lung disease ": 2.644450604344773, "Intestinal metastasis ": 31.554593352549208, "Invasive ductal breast carcinoma ": 3.5081668506748995, "Iron deficiency anaemia ": 2.583082491473178, "KL-6 increased ": 11.429160290591463, "Laboratory test abnormal ": 2.064729100183572, "Lacrimation increased ": 2.7621844351599982, "Laryngospasm ": 5.709147094284509, "Leukopenia ": 2.537065233667765, "Limb mass ": 4.803165365036792, "Lymphadenopathy mediastinal ": 10.972906287254975, "Lymphangiosis carcinomatosa ": 19.847313188314537, "Lymphoedema ": 9.580888153668855, "Madarosis ": 6.606045865529776, "Malignant neoplasm progression ": 18.001415794422723, "Malignant pleural effusion ": 20.49817889622529, "Mass ": 3.61378049065874, "Menopause ": 7.283634155248744, "Metastases to adrenals ": 7.959810491734183, "Metastases to bone ": 58.59786894763333, "Metastases to bone marrow ": 21.75721366115137, "Metastases to breast ": 42.92133690505344, "Metastases to central nervous system ": 8.379646929456335, "Metastases to eye ": 43.02271515150407, "Metastases to liver ": 28.09298526523889, "Metastases to lung ": 21.26094283943617, "Metastases to lymph nodes ": 22.129557208961096, "Metastases to meninges ": 5.704001583287627, "Metastases to ovary ": 42.62919988201436, "Metastases to pelvis ": 28.67899269633443, "Metastases to peritoneum ": 14.683666866126794, "Metastases to pleura ": 29.299990245235925, "Metastases to retroperitoneum ": 46.88225855015713, "Metastases to skin ": 49.99263942988155, "Metastases to spine ": 31.372114579649264, "Metastasis ": 21.737343461616373, "Metastatic neoplasm ": 9.008988128446756, "Micturition urgency ": 2.0256556982193974, "Muscle disorder ": 2.212891547088625, "Musculoskeletal chest pain ": 3.363373594974164, "Musculoskeletal pain ": 3.331166283301034, "Neoplasm malignant ": 2.3036640622120026, "Neoplasm progression ": 18.545883051019374, "Neoplasm recurrence ": 12.951661827650351, "Nerve injury ": 2.9801828876678647, "Neuropathy peripheral ": 3.2777487800950404, "Neutropenia ": 6.297976041067533, "Neutrophil count decreased ": 5.534118127648292, "Nodule ": 2.320247137948398, "Oestradiol increased ": 47.44933469930247, "Onychoclasis ": 10.256181100661582, "Onycholysis ": 13.875084389138015, "Osteonecrosis of jaw ": 5.800514772958016, "Pathological fracture ": 4.184496737752419, "Peripheral artery thrombosis ": 6.618018402267256, "Platelet count decreased ": 2.942446683226601, "Pleural effusion ": 4.804916245286972, "Product administered at inappropriate site ": 2.78276627057596, "Pulmonary embolism ": 2.0974131499327986, "Pulmonary mass ": 2.840537043293524, "Recurrent cancer ": 12.052633135715649, "Red blood cell count decreased ": 4.756909203148442, "Retinal vein occlusion ": 2.0723088938119933, "Sciatic nerve injury ": 17.58374903252399, "Sciatica ": 13.597141569898136, "Second primary malignancy ": 3.717046183262071, "Skin mass ": 2.422801549014618, "Skin odour abnormal ": 4.505935092948431, "Small intestinal obstruction ": 2.094098128506233, "Stomatitis ": 2.4537005814080484, "Terminal state ": 3.1303305151578966, "Throat tightness ": 2.2274904493956744, "Thyroid mass ": 3.3004081428988896, "Tooth disorder ": 2.627646482387695, "Tooth infection ": 4.251293909990223, "Trigger finger ": 6.558724169858598, "Tumour flare ": 39.26992092736663, "Tumour marker abnormal ": 58.23685796226458, "Tumour marker increased ": 110.92780135158068, "Urine odour abnormal ": 9.4735527255027, "Uterine cancer ": 2.462793266721403, "Vulvovaginal dryness ": 11.457254571015572, "Weight fluctuation ": 3.558198188071976, "White blood cell count abnormal ": 3.0729492724908445, "White blood cell count decreased ": 5.9082204564764655}
\ No newline at end of file
+{"Abnormal sensation in eye": 15.951871935728416, "Acute myocardial infarction": 2.978057786102086, "Age-related macular degeneration": 97.08277617972388, "Amaurosis": 24.41496107824563, "Amaurosis fugax": 45.61128102611088, "Angle closure glaucoma": 5.011210795054187, "Anterior chamber cell": 220.4042150215594, "Anterior chamber disorder": 257.28213530889286, "Anterior chamber fibrin": 92.53621652153348, "Anterior chamber flare": 113.56171367092536, "Anterior chamber inflammation": 218.05391238939964, "Bacterial endophthalmitis": 485.866658994033, "Blepharitis": 7.001891859039442, "Blindness": 43.813450473926906, "Blindness transient": 252.19620207983945, "Blindness unilateral": 144.4170743073148, "Brain stem infarction": 9.132716233284764, "Carotid artery stenosis": 4.319689214498798, "Cataract": 11.083478599867084, "Cataract operation": 33.26425676950349, "Cataract subcapsular": 27.34296608596833, "Cerebellar infarction": 7.503559469208704, "Cerebral infarction": 20.01484590455702, "Cerebrovascular accident": 4.653653346968966, "Chorioretinitis": 36.38977796609247, "Choroidal detachment": 35.591800072718335, "Choroidal neovascularisation": 137.79605809004923, "Ciliary hyperaemia": 159.08912861663364, "Conjunctival haemorrhage": 21.50838740417052, "Conjunctival hyperaemia": 8.679608134299755, "Conjunctivitis": 2.2246829258318703, "Corneal abrasion": 79.21810259243514, "Corneal deposits": 17.64183311629418, "Corneal disorder": 27.68209004360984, "Corneal epithelium defect": 29.884750849975287, "Corneal oedema": 86.30894206872341, "Corneal opacity": 22.831353199241736, "Cystoid macular oedema": 22.43938705838714, "Death": 2.203936944643836, "Dementia": 2.5052528766659714, "Detachment of retinal pigment epithelium": 372.9170308702866, "Device difficult to use": 6.087421919435592, "Device use issue": 217.29945487963525, "Diabetic retinal oedema": 124.91524416884388, "Diabetic retinopathy": 3.009792118838931, "Dry age-related macular degeneration": 122.14711884575792, "Dry eye": 3.499352809416769, "Dyslalia": 12.0390694390926, "Endophthalmitis": 1942.594553388283, "Epiretinal membrane": 33.33584119321566, "Eye discharge": 13.288184770012515, "Eye disorder": 9.146482332862528, "Eye haemorrhage": 32.40685679091044, "Eye infection": 39.06240770945119, "Eye infection bacterial": 129.10181067704144, "Eye infection intraocular": 87.93990329567666, "Eye infection staphylococcal": 454.56823802190894, "Eye inflammation": 254.59335269455383, "Eye injury": 8.226479915143292, "Eye irritation": 10.467002038390886, "Eye oedema": 13.806020929066651, "Eye operation": 8.09754900950883, "Eye pain": 28.5941522060994, "Eye swelling": 3.95927258470806, "Foreign body in eye": 88.505671666285, "Foreign body sensation in eyes": 43.32788307392756, "Glaucoma": 5.143439430619032, "Haemorrhagic stroke": 2.517393947639739, "Hemiparesis": 2.189341382191776, "Hemiplegia": 6.701384233483764, "Hyphaema": 42.69121250321484, "Hypopyon": 480.09103713237, "Hypotony of eye": 193.7458312965939, "Inadequate aseptic technique in use of product": 686.9862716449983, "Inappropriate schedule of product administration": 2.0417345752869944, "Injection site discomfort": 5.25466761251131, "Injection site haemorrhage": 4.886709184530151, "Intentional dose omission": 2.9997122816033284, "Intra-ocular injection complication": 1404.0500274868111, "Intraocular pressure decreased": 302.0983636445462, "Intraocular pressure increased": 193.9532822944248, "Iridocyclitis": 79.60853766071563, "Iritis": 110.44677006867646, "Ischaemic stroke": 5.046795778781116, "Keratic precipitates": 115.2016761175119, "Keratitis": 11.271441485141237, "Lacrimation increased": 8.311812188743762, "Lacunar infarction": 10.414512681061057, "Macular degeneration": 6.595572038170715, "Macular fibrosis": 251.1990643080358, "Macular hole": 133.9869974972446, "Macular oedema": 43.90346847102105, "Maculopathy": 14.333059867877385, "Metamorphopsia": 74.87729792815857, "Multiple use of single-use product": 391.0617514444264, "Myocardial infarction": 2.8227516163703674, "Neovascular age-related macular degeneration": 129.69501153697115, "Non-infectious endophthalmitis": 5223.587249057282, "Ocular discomfort": 11.368129053437722, "Ocular hyperaemia": 16.4719984241656, "Ocular hypertension": 86.2064115385778, "Ocular procedural complication": 610.573408963839, "Ocular vasculitis": 90.78846820066109, "Photophobia": 6.237245659391273, "Photopsia": 9.574374371771064, "Polypoidal choroidal vasculopathy": 1001.190882381094, "Posterior capsule opacification": 67.87368499748167, "Product contamination": 11.975743672888322, "Product dose omission issue": 2.622909495877075, "Product prescribing issue": 3.4863876344525475, "Pseudoendophthalmitis": 1819.859413821768, "Refusal of treatment by patient": 13.901648158701931, "Retinal artery occlusion": 94.06121448711548, "Retinal degeneration": 65.43664434958252, "Retinal detachment": 26.493331315625667, "Retinal disorder": 15.35556104109066, "Retinal exudates": 24.197769892587285, "Retinal haemorrhage": 76.52883799662915, "Retinal ischaemia": 23.228933000531068, "Retinal neovascularisation": 130.0874016000184, "Retinal oedema": 120.5495704471347, "Retinal pigment epithelial tear": 2407.0856342317343, "Retinal pigment epitheliopathy": 57.25718063344213, "Retinal scar": 140.03188575034645, "Retinal tear": 36.77513999591394, "Retinal thickening": 334.7205018796414, "Retinal vascular disorder": 29.075074191409005, "Retinal vascular occlusion": 25.032764668497386, "Retinal vasculitis": 39.34327991532334, "Retinal vein occlusion": 13.584451709170647, "Scleritis": 14.616764495066128, "Serous retinal detachment": 44.758356534613576, "Staphylococcus test positive": 13.171078332219569, "Streptococcal infection": 7.106243481482463, "Subretinal fluid": 264.26403479192027, "Sudden visual loss": 60.43747962727947, "Suspected product quality issue": 19.89031333954573, "Swelling of eyelid": 4.1145403463604495, "Syringe issue": 28.84730945603805, "Therapeutic product ineffective": 4.799613353660498, "Thrombotic cerebral infarction": 36.69414944406294, "Toxic anterior segment syndrome": 29.816399307331, "Transient ischaemic attack": 7.289906434768197, "Ulcerative keratitis": 7.643247882984557, "Uveitis": 98.49983055842354, "Vision blurred": 12.061917123536976, "Visual acuity reduced": 106.81590775761602, "Visual acuity reduced transiently": 205.05239809757876, "Visual field defect": 9.66374995651324, "Visual impairment": 15.070612886689656, "Vitreal cells": 605.7148111016025, "Vitrectomy": 2302.14169630413, "Vitreous detachment": 28.304706740628085, "Vitreous disorder": 187.13640036231493, "Vitreous floaters": 98.647890454117, "Vitreous haemorrhage": 104.26899731433686, "Vitreous opacities": 296.55481735337685, "Vitritis": 341.35935919575303, "Wrong technique in product usage process": 6.928798483857624}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/461.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/461.json
index a6493718ed6..2e6b7408f4a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/461.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/461.json
@@ -1 +1 @@
-{"Anaphylactic reaction ": 5.574614210389711, "Anaphylactic shock ": 16.892588066902487, "Blood bilirubin increased ": 9.020605055814965, "Blood pressure decreased ": 3.5457856302223734, "Blood uric acid increased ": 59.56608188824778, "Bronchospasm ": 34.28335993372861, "Erythema ": 2.8807628336855995, "Glucose-6-phosphate dehydrogenase deficiency ": 995.870006735314, "Haemolysis ": 127.16543489514792, "Haemolytic anaemia ": 158.64867509702987, "Hepatic cytolysis ": 13.067967373960176, "Hyperhidrosis ": 2.6947521239337107, "Hypersensitivity ": 5.776898181662395, "Hypertriglyceridaemia ": 56.7835595759765, "Hypotension ": 4.933325916815454, "Methaemoglobinaemia ": 2326.180366476596, "Oxygen saturation decreased ": 11.494452366391998, "Respiratory failure ": 5.1075895635397925, "Thrombocytopenia ": 2.26385595340561, "Tumour lysis syndrome ": 52.99487645992284}
\ No newline at end of file
+{"Confusional state": 4.7280342313327886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/462.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/462.json
index b7cce0d652f..8b1efc529ee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/462.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/462.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 7.108204797090248, "Acute kidney injury ": 4.005754327398509, "Acute myocardial infarction ": 21.613647337196824, "Angina pectoris ": 3.3446336817222884, "Blood creatine phosphokinase increased ": 3.293127864291897, "Blood creatinine increased ": 2.9787129082923007, "Blood urea increased ": 3.647447341047908, "Blood uric acid increased ": 10.315619217620414, "Cardiac failure ": 4.268200564347088, "Cardiac failure congestive ": 5.467350971924363, "Cellulitis ": 2.1137575478070527, "Cerebrovascular accident ": 2.759200813196794, "Coronary artery disease ": 8.957164346603985, "Drug eruption ": 8.88118744589666, "Drug interaction ": 3.087663455570989, "Drug reaction with eosinophilia and systemic symptoms ": 5.735128153546387, "Drug-induced liver injury ": 16.90077750493516, "Eosinophilia ": 3.658325672210787, "Gout ": 90.03909919508094, "Hepatic enzyme increased ": 2.880551215072052, "Hepatic failure ": 3.566373352290183, "Hepatic function abnormal ": 10.761300746992374, "Hepatitis acute ": 11.846524798139164, "Hyperkalaemia ": 3.0064749936535566, "Hypersensitivity vasculitis ": 37.9628319273163, "Jaundice ": 2.659373579356497, "Liver disorder ": 6.650367268911463, "Liver function test abnormal ": 6.175604854779799, "Liver injury ": 5.979765053244534, "Lung neoplasm malignant ": 3.855896899204271, "Melaena ": 2.226279260344153, "Myocardial infarction ": 5.898233011785821, "Nephrolithiasis ": 3.474103664860489, "Oedema peripheral ": 2.0153264957652595, "Pancytopenia ": 5.428976435862894, "Platelet count decreased ": 2.8055667966060978, "Prescribed underdose ": 8.9209062405223, "Procedural haemorrhage ": 48.5525773713977, "Pulmonary haemorrhage ": 15.529225430457023, "Rash ": 2.7367717843010047, "Rash maculo-papular ": 2.8490280836336064, "Renal failure ": 2.870292419130249, "Renal impairment ": 5.16916590349279, "Renal tubular necrosis ": 12.729132856234658, "Rhabdomyolysis ": 13.469588248387131, "Sepsis ": 2.1847203135731004, "Stevens-Johnson syndrome ": 11.081747040054172, "Thrombocytopenia ": 2.1736411903379147, "Toxic epidermal necrolysis ": 6.188260503623746, "Transaminases increased ": 2.3425892250300486, "Tubulointerstitial nephritis ": 8.222750106862218, "Underdose ": 4.828899641593568, "Wrong technique in product usage process ": 2.6376589170415925}
\ No newline at end of file
+{"Balance disorder": 17.061613810611448, "Condition aggravated": 2.717601902745883, "Constipation": 2.2648720019344477, "Dysstasia": 7.655010928740602, "Encephalopathy": 6.542838570896499, "Excessive granulation tissue": 811.0982281260475, "Fall": 7.7689711222058415, "Gait disturbance": 14.21647948713964, "Gait inability": 5.978552544820518, "Generalised tonic-clonic seizure": 11.65399367869762, "Loss of consciousness": 2.000230870522895, "Loss of personal independence in daily activities": 3.0102149107026435, "Medical device site discharge": 4436.643070289055, "Medical device site erosion": 2704.271097350109, "Medical device site infection": 944.4046531340248, "Mobility decreased": 6.415137612286107, "Multiple sclerosis": 34.75634760554862, "Multiple sclerosis relapse": 18.416880905597733, "Muscular weakness": 5.029474515911486, "Musculoskeletal stiffness": 2.989313744667246, "Neurotoxicity": 15.890887142486475, "Pollakiuria": 5.931940916156075, "Product substitution issue": 60.77426743591488, "Seizure": 2.2318163014781525, "Staphylococcal infection": 17.74879486115874, "Status epilepticus": 12.605258572806523, "Therapy cessation": 37.72586113632104, "Tremor": 2.157270502674732, "Urinary tract infection": 3.3210228222224587, "Wound dehiscence": 210.17914583594228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/463.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/463.json
index f87424d4e43..18b59f934ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/463.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/463.json
@@ -1 +1 @@
-{"Therapy non-responder ": 36.52501155175752, "Vaccination site pain ": 4.011770971260221}
\ No newline at end of file
+{"Accident": 10.077462232954735, "Acute disseminated encephalomyelitis": 14.197583487774455, "Ankle fracture": 5.19541312017541, "Ataxia": 2.711747343660872, "Balance disorder": 11.354083972708878, "Bladder disorder": 23.535713947017545, "Blood iron decreased": 4.116620592037755, "Blood test abnormal": 5.659382746614279, "Brain neoplasm": 3.6720205085672193, "Caesarean section": 3.21063739457929, "Central nervous system lesion": 8.342384960998306, "Constipation": 2.366023945364822, "Coronavirus infection": 23.25502477499112, "Cystitis": 17.69065796135246, "Cystitis noninfective": 29.167895965837065, "Dermatomyositis": 8.366307068445371, "Dizziness": 2.026360842243476, "Drug ineffective": 2.482962090614416, "Dysgraphia": 4.57018111326474, "Dysstasia": 7.532376919997846, "Electric shock sensation": 2.326474101333175, "Epilepsy": 7.1586094707892265, "Euphoric mood": 4.08398472079152, "Extra dose administered": 3.890650974525132, "Facial pain": 6.99451675737047, "Fall": 5.393362053049131, "Feeling abnormal": 2.1504662659972977, "Feeling of despair": 5.179075140702104, "Fine motor skill dysfunction": 10.186044891174722, "Gait disturbance": 15.29947204276483, "Gait inability": 11.160871110785877, "Gastrointestinal disorder": 3.20535093093746, "Gastrointestinal pain": 2.087319802945844, "General physical health deterioration": 2.6684746289892254, "General symptom": 11.958999521844198, "Generalised tonic-clonic seizure": 4.795748504359378, "Head injury": 2.1836017515404404, "Hemiparesis": 2.2582485908300614, "Hip fracture": 6.351338629766888, "Hypertonic bladder": 12.440613729835611, "Incontinence": 4.919130850829294, "Inflammatory marker increased": 5.805344025877565, "Initial insomnia": 2.771362875473496, "Insomnia": 4.460424396295229, "Intentional dose omission": 4.247959276700852, "Intentional product misuse": 3.2404317007358343, "Intentional underdose": 17.643092441266454, "Intervertebral disc protrusion": 3.758136549012384, "Invasive ductal breast carcinoma": 7.686912450399617, "Joint injury": 2.0171236454140304, "Kidney infection": 2.2008181046620825, "Ligament sprain": 8.953199418092316, "Liver function test increased": 2.2115477223623365, "Loss of control of legs": 43.21315495784575, "Loss of therapeutic response": 27.00085346917579, "Lower limb fracture": 4.54896006127693, "Lymphocyte count decreased": 8.254085991891813, "Lymphopenia": 8.918996018105638, "Magnetic resonance imaging abnormal": 14.733252593584226, "Mental disorder": 3.164981691807969, "Micturition urgency": 4.092744438111777, "Mobility decreased": 13.280244798278927, "Motor dysfunction": 29.07872692211426, "Multiple sclerosis": 55.673392988000536, "Multiple sclerosis relapse": 65.04560947905242, "Muscle atrophy": 2.6581365942979693, "Muscle fatigue": 2.5036250952349213, "Muscle spasms": 3.234444493991324, "Muscle spasticity": 32.25305937469725, "Muscle tightness": 6.344048728152743, "Muscular weakness": 3.831342606880104, "Musculoskeletal disorder": 23.03025692260576, "Nasopharyngitis": 3.12689237824102, "Nephrolithiasis": 3.177163102106419, "Neuralgia": 2.805897543855272, "Paraparesis": 8.253403357362089, "Partial seizures": 3.044180969155387, "Peroneal nerve palsy": 8.642878611179482, "Poor quality sleep": 15.779116828344048, "Prescribed underdose": 17.55742788952833, "Primary progressive multiple sclerosis": 614.6092962228823, "Product dose omission in error": 35.21709743151953, "Product dose omission issue": 6.629809341816412, "Product residue present": 9.357732284769003, "Progressive multifocal leukoencephalopathy": 6.026203641548, "Progressive multiple sclerosis": 152.63946659739963, "Restless legs syndrome": 3.873817295404484, "Secondary progressive multiple sclerosis": 421.45583356061866, "Seizure": 2.569076661015304, "Sensory disturbance": 3.253051744971218, "Sleep disorder": 3.97486447837996, "Speech disorder": 2.3989415411209585, "Status epilepticus": 9.804433619133746, "Stem cell transplant": 33.71627927058602, "Stress": 2.040098117159626, "Temperature intolerance": 12.002922216637192, "Terminal state": 6.324523773747727, "Therapeutic product effect decreased": 5.3262657007521, "Therapeutic response shortened": 10.480044130453251, "Therapy non-responder": 17.970645697304427, "Toothache": 2.7609608745253147, "Trigeminal neuralgia": 31.552796554408527, "Uhthoff's phenomenon": 199.7893807329177, "Underdose": 27.42090909535563, "Upper limb fracture": 3.5727269769949377, "Urinary incontinence": 4.403514928047489, "Urinary tract disorder": 6.581052674154903, "Urinary tract infection": 8.866238417162329, "Urinary tract obstruction": 31.134075646569173, "Urosepsis": 4.775203301896718, "Vertigo": 2.1145153757809405, "Vitamin D deficiency": 5.135520900775227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/464.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/464.json
index 1ec77930e51..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/464.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/464.json
@@ -1 +1 @@
-{"Abortion induced ": 4.2071146256265815, "Abscess neck ": 20.64842232043754, "Accidental death ": 6.42308397006293, "Accidental overdose ": 7.2996733370029565, "Acute hepatic failure ": 2.4535375489450595, "Acute postoperative sialadenitis ": 140.24359105862902, "Acute pulmonary oedema ": 5.019668337241424, "Acute respiratory distress syndrome ": 3.383247071842733, "Acute respiratory failure ": 2.5682955349649728, "Agitation ": 2.5947463163062165, "Agoraphobia ": 6.628425222830841, "Air embolism ": 25.09130461032556, "Airway complication of anaesthesia ": 43.75810272349158, "Airway peak pressure increased ": 104.37878587281892, "Alcohol poisoning ": 9.248621321884372, "Allodynia ": 11.039151617949608, "Amphetamines positive ": 104.61975909858396, "Anaesthetic complication ": 17.957182115850124, "Anaesthetic complication neurological ": 6.453731344829355, "Anaphylactic reaction ": 8.240833694520294, "Anaphylactic shock ": 5.619690709521088, "Anaphylactoid reaction ": 7.430705083076045, "Anaphylactoid shock ": 3.826588555309565, "Anisocoria ": 8.32515792633657, "Anterior spinal artery syndrome ": 103.42466271312291, "Anticholinergic syndrome ": 8.217520547646828, "Anuria ": 2.5494728896214656, "Anxiety disorder ": 3.0424164833954426, "Apgar score abnormal ": 47.98164838974555, "Apgar score low ": 48.86600054913171, "Apnoea ": 14.506630989042293, "Apnoeic attack ": 16.41262609313192, "Arachnoiditis ": 14.485197907476818, "Areflexia ": 6.642433644537372, "Arteriospasm coronary ": 6.20954473958047, "Arthritis bacterial ": 2.8722758902854246, "Asphyxia ": 2.912225358882385, "Atelectasis ": 2.038881015674296, "Atrioventricular block complete ": 4.97308995454824, "Atrioventricular block second degree ": 6.251679778542808, "Autonomic dysreflexia ": 49.41700036750469, "Autonomic nervous system imbalance ": 4.7465139538698695, "Bispectral index decreased ": 231.2706188708904, "Blood albumin decreased ": 2.2674013621058693, "Blood ethanol ": 1060.8809749451864, "Blood ethanol increased ": 58.98155573860414, "Blood lactic acid increased ": 2.053322171063751, "Blood magnesium decreased ": 2.522379773436788, "Blood pressure decreased ": 5.111107537229279, "Blood pressure immeasurable ": 8.627357701117285, "Blood pressure systolic decreased ": 10.368423565883402, "Bradycardia ": 6.765244552111261, "Bradycardia foetal ": 55.22735867175306, "Bradypnoea ": 2.1766872591886703, "Brain death ": 4.545313071191781, "Brain herniation ": 2.627961663211538, "Brain injury ": 4.670279217715022, "Brain oedema ": 2.3208668665919894, "Breakthrough pain ": 8.470038123728326, "Bronchospasm ": 9.853061391939509, "Bundle branch block left ": 3.320140851574768, "Bundle branch block right ": 2.224249063477062, "Caesarean section ": 6.348876033352314, "Carbon dioxide decreased ": 5.262965340808649, "Carbon dioxide increased ": 5.111180079081104, "Carcinoid crisis ": 30.788693596009043, "Carcinoid tumour ": 9.24313640406652, "Cardiac arrest ": 8.814090582817029, "Cardiac death ": 44.002471369857226, "Cardiac dysfunction ": 2.4032192247223905, "Cardiac hypertrophy ": 4.756330496655121, "Cardio-respiratory arrest ": 6.978938647806461, "Cardiogenic shock ": 2.469325583894748, "Cardiomegaly ": 2.3016551892751624, "Cerebrospinal fluid leakage ": 5.50975895025987, "Chest injury ": 3.4745002250455737, "Circulatory collapse ": 3.966666548262004, "Clonus ": 14.393011263304532, "Coagulopathy ": 2.2446732471581963, "Coma ": 2.759728625273288, "Coma scale abnormal ": 3.974613394032374, "Communication disorder ": 2.6818842977971213, "Compartment syndrome ": 7.298027924456704, "Completed suicide ": 3.276610567482437, "Conversion disorder ": 5.340141580600066, "Counterfeit product administered ": 24.72306468004015, "Crohn's disease ": 2.2393354674762733, "Cyanosis ": 2.88588155336766, "Death ": 2.066776364737558, "Delayed recovery from anaesthesia ": 65.69867556016085, "Delirium ": 3.1719856674621023, "Dependence ": 12.019595835912796, "Depressed level of consciousness ": 3.888916619398965, "Developmental delay ": 2.872340659376473, "Device failure ": 2.0016407519603767, "Diabetes insipidus ": 3.220891315573557, "Diastolic dysfunction ": 3.887313282828965, "Diffuse alveolar damage ": 6.016019842189261, "Diplegia ": 3.265968730831285, "Drug abuse ": 17.29344793210555, "Drug dependence ": 11.887994963104846, "Drug detoxification ": 24.90546835726349, "Drug diversion ": 16.69725031820183, "Drug interaction ": 4.036481172856109, "Drug level increased ": 2.729705811669638, "Drug screen positive ": 3.08417551425806, "Drug tolerance ": 34.39693456231795, "Drug tolerance increased ": 23.710588322222087, "Drug use disorder ": 12.25285214192226, "Drug withdrawal syndrome ": 9.800891134834744, "Drug withdrawal syndrome neonatal ": 5.2008662295247285, "Drug-genetic interaction ": 43.36408383041438, "Duodenitis ": 2.5523132622547764, "Dysarthria ": 2.4714655861900905, "Dyskinesia ": 2.161877941377553, "Dysphemia ": 2.8303114303977708, "Electrocardiogram P wave abnormal ": 20.19664212181884, "Electrocardiogram ST segment depression ": 20.669784717168607, "Electrocardiogram ST segment elevation ": 9.770150398323102, "Electrocardiogram T wave abnormal ": 4.756330496655121, "Electrocardiogram T wave amplitude decreased ": 16.028168028548233, "Electrocardiogram T wave inversion ": 4.420116069736779, "Electrocardiogram abnormal ": 4.748316750827945, "Electroencephalogram abnormal ": 4.992944654996113, "Emotional disorder ": 4.022202891379808, "End-tidal CO2 decreased ": 52.4928000562922, "End-tidal CO2 increased ": 225.31315390040407, "Endometriosis ": 2.128864621206541, "Euphoric mood ": 4.371573184279029, "Ewing's sarcoma ": 24.16509020851709, "Exposure during pregnancy ": 6.42488915295431, "Extensor plantar response ": 3.9304131438209375, "Extradural abscess ": 29.339257030381468, "Extradural haematoma ": 3.016220632478895, "Extravasation ": 3.6286833879492537, "Faecaloma ": 3.01628314105686, "Fibrin D dimer increased ": 2.531645014641277, "Foaming at mouth ": 2.240787056722896, "Foetal death ": 7.377978935306902, "Foetal distress syndrome ": 6.858775124066405, "Foetal exposure during delivery ": 35.092797117903395, "Foetal exposure during pregnancy ": 6.353202509714267, "Foetal exposure timing unspecified ": 4.532497540841885, "Foetal growth restriction ": 2.7118104232897347, "Foetal heart rate abnormal ": 10.61756680091137, "Foetal heart rate deceleration abnormality ": 54.11360628368904, "Foetal heart rate decreased ": 31.12576914329544, "Foetal hypokinesia ": 4.788915631246089, "Foreign body reaction ": 49.784648327956766, "Functional gastrointestinal disorder ": 19.151315494064114, "Gastric dilatation ": 38.80431604176108, "Generalised tonic-clonic seizure ": 3.3452474080702075, "Glassy eyes ": 10.549928416565864, "Globulins increased ": 26.93083447647913, "Glossoptosis ": 13.44333609696427, "Gun shot wound ": 5.6548003834943055, "Haemodynamic instability ": 10.61494733359656, "Heart rate decreased ": 3.0916025010631323, "Hemiplegic migraine ": 14.850888533746913, "Homeless ": 63.09294832643059, "Horner's syndrome ": 64.93945018368528, "Hyperaesthesia ": 7.850210768641397, "Hypercapnia ": 18.248957998829145, "Hyperdynamic left ventricle ": 25.32730947348779, "Hyperreflexia ": 4.393008914264482, "Hypertensive heart disease ": 3.068442710570729, "Hyperthermia ": 2.203080097132748, "Hyperthermia malignant ": 87.38915253841068, "Hypertonia ": 2.2559107192483365, "Hypopnoea ": 3.9371500958496126, "Hypotension ": 6.427012657461907, "Hypothermia ": 3.547473153398565, "Hypotonia neonatal ": 5.272014947658747, "Hypoventilation ": 15.435268910019031, "Hypoxia ": 5.541835219371921, "Hypoxic-ischaemic encephalopathy ": 10.731963761292471, "Ileus ": 2.458098054895996, "Impaired driving ability ": 4.005052646931335, "Implant site extravasation ": 11.508013788723003, "Implant site infection ": 7.811672384566375, "Implant site pain ": 12.44916203590515, "Inadequate analgesia ": 17.05233650416307, "Incorrect drug administration rate ": 2.596427325467257, "Incorrect route of product administration ": 11.544105258675051, "Increased bronchial secretion ": 7.792482361240531, "Infantile apnoea ": 6.199417624623381, "Infusion site extravasation ": 2.8897352579019158, "Infusion site mass ": 23.9578032001368, "Inspiratory capacity decreased ": 193.44620542160672, "Intensive care unit acquired weakness ": 56.58658394473184, "Intentional product misuse ": 6.378797461038319, "Intentional underdose ": 2.8870371784719087, "Intestinal stenosis ": 5.955685836066354, "Judgement impaired ": 4.735597189916646, "Laryngeal obstruction ": 26.990544399668916, "Laryngospasm ": 11.347953238655776, "Learning disability ": 14.244939598272488, "Lip ulceration ": 5.351134311401888, "Live birth ": 12.979508841692985, "Loss of consciousness ": 2.154797297701909, "Loss of employment ": 5.287964521708748, "Low birth weight baby ": 11.956497498762486, "Maternal exposure during delivery ": 34.60321775898639, "Maternal exposure during pregnancy ": 3.5402526692869505, "Maternal exposure timing unspecified ": 8.419994895328559, "Mean arterial pressure decreased ": 40.533543464208, "Mechanical ventilation ": 3.632316812850788, "Mechanical ventilation complication ": 25.83484401047674, "Medical device discomfort ": 28.25812347954277, "Medication error ": 2.242022671841251, "Meningitis bacterial ": 4.975531752367867, "Mental impairment ": 3.650724815348212, "Mental status changes ": 3.38568436795332, "Mental status changes postoperative ": 183.23582245372936, "Metabolic acidosis ": 2.8832795303616634, "Miosis ": 5.749754174117107, "Mucosal ulceration ": 5.451851313915949, "Multiple-drug resistance ": 2.277454642999196, "Muscle rigidity ": 5.948349740943895, "Muscle tension dysphonia ": 314.2128633340365, "Mydriasis ": 6.625640480151256, "Myocardial ischaemia ": 3.346437421271826, "Myoclonus ": 7.611023273666915, "Myoglobin urine present ": 23.217841444389503, "Near death experience ": 2.0506677416020453, "Negative pressure pulmonary oedema ": 56.00423894665031, "Neonatal asphyxia ": 22.532570472543192, "Neonatal disorder ": 37.92941563518856, "Neonatal respiratory depression ": 26.817869729866047, "Neonatal respiratory distress syndrome ": 4.426249098648336, "Neuromuscular block prolonged ": 38.00750708633272, "Neuromuscular blockade ": 14.29982238485408, "Neurotoxicity ": 2.2358258002870186, "Nodal rhythm ": 3.9543557923764863, "Non-cardiogenic pulmonary oedema ": 24.41356537493828, "Nonreassuring foetal heart rate pattern ": 31.56208891603267, "Normal newborn ": 2.2290312082333186, "Nystagmus ": 3.4946520636026346, "Obstructive airways disorder ": 3.5871798139939344, "Oligohydramnios ": 3.814538290374758, "Opiates positive ": 159.00956045926398, "Optic neuropathy ": 2.9427098556537303, "Oral mucosa erosion ": 7.29917373500387, "Overdose ": 8.098521277133903, "Oxygen saturation abnormal ": 3.596827998485142, "Oxygen saturation decreased ": 6.764085227172628, "PCO2 increased ": 22.146796648540803, "PO2 decreased ": 7.283054513893038, "Palatal oedema ": 2.317367865057454, "Paralysis ": 2.978347207075359, "Paraplegia ": 6.703989195356158, "Pathological fracture ": 3.1348902050892264, "Peripheral nerve injury ": 8.878903296595146, "Personal relationship issue ": 12.149594455958894, "Pharyngeal hypoaesthesia ": 10.43780825965789, "Pharyngeal paraesthesia ": 5.064529233621383, "Piloerection ": 11.250486260647172, "Placental transfusion syndrome ": 81.05291178788833, "Pneumomediastinum ": 4.810580710742442, "Pneumonia klebsiella ": 4.227290972781793, "Pneumonitis aspiration ": 7.207044266393752, "Pneumothorax ": 3.6752909157471545, "Poisoning ": 2.2961316950707533, "Polyhydramnios ": 6.061605785391556, "Poor quality product administered ": 3.316362977451846, "Post lumbar puncture syndrome ": 6.156961969546647, "Post procedural complication ": 9.0085269394889, "Post-traumatic stress disorder ": 4.977870474441823, "Postmortem blood drug level ": 1503.0517445598343, "Postmortem blood drug level increased ": 51.36534182441573, "Postoperative delirium ": 17.049781696539725, "Postpartum haemorrhage ": 5.619038551548635, "Potentiating drug interaction ": 6.544467520121809, "Pre-eclampsia ": 3.1789544420932403, "Pregnancy ": 2.0975540920171123, "Premature baby ": 11.979472137574987, "Premature delivery ": 8.013375404072494, "Premature labour ": 3.516427589228427, "Prescription drug used without a prescription ": 3.997754490630531, "Prinzmetal angina ": 14.71802832294206, "Procedural complication ": 5.280819042523384, "Procedural hypotension ": 68.12447363244294, "Procedural nausea ": 78.97129346318529, "Procedural pain ": 2.671830534646184, "Procedural vomiting ": 67.02332752202292, "Proctalgia ": 2.085661934963761, "Product adhesion issue ": 3.928994117267088, "Product administered at inappropriate site ": 3.613940079394489, "Product counterfeit ": 13.172184782434034, "Product 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6.116253588701886, "Sedation complication ": 5.152587982187614, "Seizure like phenomena ": 4.792844770596524, "Sensory loss ": 2.9404683693109024, "Serotonin syndrome ": 10.94243491644446, "Sinus arrest ": 3.214163361885351, "Sinus bradycardia ": 2.5411742579222394, "Sinus node dysfunction ": 3.796692923995449, "Skin abrasion ": 4.842838896628899, "Skin test positive ": 3.685225804978232, "Slow response to stimuli ": 2.668627871806605, "Snoring ": 5.776372096461027, "Somatic symptom disorder ": 4.019509959146072, "Somnolence ": 2.289324305510296, "Spinal cord compression ": 2.840157926403608, "Spinal cord infarction ": 36.188196491705305, "Spinal cord injury ": 13.478192536284284, "Spinal cord oedema ": 26.8421862078261, "Spinal epidural haematoma ": 6.40767431183129, "Stereotypy ": 7.884847136989245, "Stress cardiomyopathy ": 13.260817571646328, "Stridor ": 3.0890755972522137, "Stupor ": 2.546429465014924, "Substance abuse ": 22.12665117972758, "Substance dependence ": 51.45855411735601, "Substance use disorder ": 10.91022446190004, "Supraventricular tachycardia ": 2.3549809558614494, "Suspected suicide ": 3.929661550782338, "Tachycardia ": 2.3938711204929803, "Tachycardia foetal ": 11.79496559070308, "Therapeutic product effect increased ": 3.1690337924431287, "Thyrotoxic crisis ": 4.652714006793215, "Torsade de pointes ": 2.134454085751316, "Toxicity to various agents ": 16.303377521993667, "Toxicologic test abnormal ": 16.334726387681624, "Tryptase increased ": 12.732089706124317, "Type I hypersensitivity ": 2.821553222754226, "Unevaluable event ": 3.3215669157778365, "Unresponsive to stimuli ": 11.925569817864371, "Unwanted awareness during anaesthesia ": 119.16569296340666, "Upper airway obstruction ": 28.21591087237004, "Urinary retention ": 2.3402670069900107, "Urine analysis abnormal ": 4.885538665302246, "Uterine hypotonus ": 21.04183814281389, "Vasoplegia syndrome ": 5.809267835119951, "Vein collapse ": 19.32095491643746, "Ventilation perfusion mismatch ": 28.332936677229466, "Ventricular arrhythmia ": 2.031737380088883, "Ventricular extrasystoles ": 4.135826132847813, "Ventricular fibrillation ": 5.765802977874911, "Ventricular hypokinesia ": 7.549402174713726, "Ventricular tachycardia ": 6.070580028612318, "Withdrawal syndrome ": 4.755818931081166, "Wrong product administered ": 2.193926868898389, "Wrong technique in product usage process ": 2.1604952900412937, "X-ray abnormal ": 5.793442365188687}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/465.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/465.json
index 8b412eb554d..d36db408673 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/465.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/465.json
@@ -1 +1 @@
-{"Amnesia ": 32.82498513043153, "Aphasia ": 49.54845343347981, "Bradycardia ": 20.254344539294195, "Brain injury ": 172.84067716290758, "Cardiac arrest ": 14.19815081421435, "Cardiomegaly ": 78.21093456841346, "Cerebral infarction ": 51.30963731475755, "Cerebrovascular accident ": 12.30039743852318, "Drug effect less than expected ": 154.80469089025684, "Drug ineffective ": 2.252733573468947, "Dry mouth ": 8.070593073087295, "Dysstasia ": 16.552969929075235, "Electrocardiogram QRS complex prolonged ": 339.64979337597475, "Fall ": 3.317218707601008, "Fracture ": 14.77680835255884, "Hypotension ": 7.466608455221339, "Loss of consciousness ": 25.641298123479583, "Muscle spasms ": 3.0627913244552927, "Off label use ": 2.1284978363189806, "Overdose ": 31.18354674290772, "Product use in unapproved indication ": 2.2673919750005016, "Product use issue ": 11.161460207839356, "Pulseless electrical activity ": 1101.004184712733, "Syncope ": 2.217014829431105, "Tendon disorder ": 61.27244894001729, "Transient ischaemic attack ": 51.72925328426641, "Urinary incontinence ": 19.09595546932221, "Vertigo ": 3.2623678498331685}
\ No newline at end of file
+{"Acute respiratory failure": 3.2230208271739693, "Adrenal insufficiency": 2.895647095760036, "Anaphylactic reaction": 4.6894748747482735, "Appetite disorder": 5.723265962537367, "Asthma": 27.1549809808864, "Asthmatic crisis": 17.028105715046745, "Blood immunoglobulin E increased": 8.677002067949266, "Body height decreased": 3.036150390226166, "Breast cancer female": 7.1081594541652295, "Bronchial secretion retention": 11.661531773123857, "Bronchiectasis": 3.128964411946921, "Bronchitis": 3.2308682989043978, "Bronchopulmonary aspergillosis": 2.831452740571564, "Bronchospasm": 2.5753978475074804, "COVID-19 pneumonia": 2.714886671345794, "Chest discomfort": 2.29558858841391, "Chronic obstructive pulmonary disease": 2.5589706294066588, "Cough": 2.6056016605369123, "Decreased activity": 3.426422038768053, "Device defective": 18.499443453384167, "Device delivery system issue": 21.57793151431052, "Device issue": 4.163582191927951, "Device leakage": 45.04834540700293, "Device malfunction": 4.342542102775939, "Device use issue": 28.51250633612801, "Drug dose omission by device": 40.192298853426415, "Drug effect less than expected": 13.253040158480458, "Dysphonia": 3.4216996708338687, "Dyspnoea": 2.5383818815688954, "Ectopic pregnancy": 10.075088557562072, "Eczema": 2.592598906285132, "Eosinophil count abnormal": 88.0875997363502, "Eosinophil count decreased": 14.49011516925103, "Eosinophil count increased": 46.55794372924296, "Eosinophilia": 2.9571784773485668, "Eosinophilic granulomatosis with polyangiitis": 38.22006720967221, "Eye disorder": 2.430727451544555, "Forced expiratory volume decreased": 14.013334315191551, "Frustration tolerance decreased": 3.488487622535633, "Generalised oedema": 2.1056420776481617, "Hypersensitivity": 2.3905170354570493, "Illness": 2.301690986785291, "Immune system disorder": 2.351282927546486, "Inability to afford medication": 15.354684236328776, "Inappropriate schedule of product administration": 4.251118752134733, "Incorrect dose administered by device": 14.828976566696236, "Injection site haemorrhage": 3.4790447578818933, "Injection site rash": 4.202968840564676, "Insurance issue": 27.578482382301814, "Lower respiratory tract infection": 3.32124828335017, "Lung disorder": 4.142563256087541, "Middle insomnia": 4.012198023083519, "Multiple allergies": 5.327407539508856, "Nasal congestion": 3.551588319098203, "Nasal polyps": 49.43111372203657, "Nasopharyngitis": 2.5868730511887223, "Needle issue": 6.523692583374997, "Obstructive airways disorder": 3.961407723116339, "Organising pneumonia": 4.014665675776367, "Oropharyngeal discomfort": 2.61706527089436, "Oxygen saturation decreased": 3.140693268903531, "Pharyngitis": 7.431989635152971, "Pneumonia": 2.218355751323496, "Pneumonia bacterial": 3.668710854515532, "Polyneuropathy": 2.123494882678481, "Product distribution issue": 43.49793695450678, "Product dose omission issue": 7.383835470523003, "Productive cough": 4.276472459381777, "Pulmonary function test decreased": 21.714929745635786, "Pulmonary mass": 2.1914141895990418, "Pulmonary nocardiosis": 152.6776725873966, "Pulmonary pain": 3.2044042328476188, "Pustule": 2.391768157154317, "Rash pruritic": 2.4054640152628397, "Respiratory disorder": 2.1432737176251244, "Respiratory tract congestion": 2.917625099394084, "Rheumatic disorder": 4.988184396201542, "Rhinitis": 4.304935102377101, "SARS-CoV-2 test negative": 13.31751587192761, "Seasonal allergy": 2.329724868962989, "Secretion discharge": 8.826802659397945, "Serum sickness": 11.936858786794447, "Sinus disorder": 3.822118817748794, "Sinusitis": 2.9444003531689398, "Skin plaque": 2.3068494195753857, "Skin reaction": 2.4478670604501267, "Sleep disorder due to a general medical condition": 2.4278551751898463, "Symptom recurrence": 18.191868498232004, "Therapeutic product effect decreased": 2.2366400483414783, "Therapeutic response shortened": 12.33655852009904, "Throat tightness": 3.048414770157577, "Urticaria": 2.97437831395314, "Viral infection": 3.73364438327422, "Wheezing": 7.9860887689176145, "Wrong technique in device usage process": 14.47628150270339}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/466.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/466.json
index 527cdc54600..3f61717ce45 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/466.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/466.json
@@ -1 +1 @@
-{"Accidental overdose ": 2.3082973785057344, "Blood glucose abnormal ": 48.16387219679721, "Blood glucose decreased ": 18.604139531717763, "Blood glucose fluctuation ": 67.73853125733328, "Blood glucose increased ": 51.15097948118381, "Dermatitis allergic ": 2.4324985569331963, "Device breakage ": 56.77109366926445, "Device defective ": 27.124172231285534, "Device delivery system issue ": 28.747244215367296, "Device failure ": 51.78681692416048, "Device information output issue ": 327.0282534630534, "Device issue ": 27.18678435800706, "Device leakage ": 14.11204681725067, "Device malfunction ": 16.34425790201519, "Device occlusion ": 26.09973944828613, "Diabetes mellitus inadequate control ": 16.224442829860095, "Diabetic ketoacidosis ": 14.361551521574516, "Diabetic metabolic decompensation ": 34.569788537965614, "Drug delivery system issue ": 77.45257335122263, "Drug ineffective ": 5.730885508635657, "Exposure during pregnancy ": 3.109100805782613, "Extra dose administered ": 13.381476451202452, "Glycosylated haemoglobin increased ": 7.972596007124737, "Hyperglycaemia ": 40.09639672669617, "Hypoglycaemia ": 24.243658807805605, "Hypoglycaemic unconsciousness ": 20.909130686505648, "Incorrect dose administered ": 2.7544054038301087, "Incorrect dose administered by device ": 86.41306673308985, "Increased insulin requirement ": 353.48249504892163, "Infusion site erythema ": 41.26350511296162, "Infusion site inflammation ": 117.99053270573027, "Infusion site pain ": 120.95654899212178, "Infusion site pruritus ": 48.44348166416366, "Injection site atrophy ": 58.30545838476363, "Injection site bruising ": 8.974130740769215, "Injection site hypersensitivity ": 18.09600940676135, "Injection site irritation ": 40.746058343897126, "Injection site mass ": 9.35304123785286, "Injection site pruritus ": 3.2241233158346687, "Injection site rash ": 5.846281398249956, "Insulin resistance ": 56.18370107771618, "Ketoacidosis ": 5.855454631323342, "Lipodystrophy acquired ": 9.927281986718564, "Liquid product physical issue ": 420.4859578835674, "Maternal exposure during pregnancy ": 3.7175474671029263, "Pain of skin ": 2.567970792699055, "Product appearance confusion ": 484.1838787489507, "Product colour issue ": 60.56367525498494, "Product deposit ": 192.5742350082225, "Product dispensing error ": 4.511898013930061, "Product gel formation ": 1916.530692084404, "Product leakage ": 30.916721805438318, "Product physical issue ": 58.579206366307375, "Product quality issue ": 29.742685640781005, "Product storage error ": 16.45900668133971, "Therapeutic product effect decreased ": 10.722730805040737, "Therapeutic product effect delayed ": 150.4986571043564, "Therapeutic product effect variable ": 53.12841230499329, "Thirst ": 4.151856781163862, "Weight increased ": 2.7027494550528663, "Wrong product administered ": 48.52442661959076, "Wrong technique in device usage process ": 9.875135843276365, "Wrong technique in product usage process ": 6.770485719468444}
\ No newline at end of file
+{"Acute hepatic failure": 2.549841086503624, "Alopecia": 2.8391587700217342, "Aphthous ulcer": 2.233462885937823, "Ascites": 3.364064570154216, "Back pain": 2.482402670859799, "Blood oestrogen increased": 18.732033865902597, "Body height decreased": 12.634529260026987, "Bone cancer": 14.065671282392316, "Bone cancer metastatic": 49.58146340817728, "Bone lesion": 18.20638479313589, "Bone pain": 5.604026645001703, "Breast cancer": 4.947904493670108, "Breast cancer female": 16.863543192432665, "Breast cancer metastatic": 27.57988946072983, "Breast cancer recurrent": 94.13303397037812, "Breast cancer stage IV": 72.79669239188901, "Breast mass": 3.74193977162639, "Bronchiectasis": 2.5575364851562608, "Bundle branch block left": 2.128635403746267, "Cancer pain": 14.882679219191193, "Carbohydrate antigen 15-3 increased": 67.47630375907038, "Carcinoembryonic antigen increased": 6.596380498070178, "Carpal tunnel syndrome": 2.2254393770234486, "Circumstance or information capable of leading to medication error": 2.3052435183439166, "Constipation": 2.2391746957387717, "Cough": 2.5500460613993314, "Cytopenia": 2.9875819575683225, "Decubitus ulcer": 2.1597540566125097, "Disease progression": 5.957369287814216, "Dry skin": 3.128372268005105, "Dysstasia": 2.09966541174101, "Embolism": 2.9769294437352274, "Femur fracture": 2.9607421653863133, "Full blood count abnormal": 4.857797451427605, "Full blood count decreased": 6.016758305898734, "Gait disturbance": 2.2558954248815235, "Haemoglobin decreased": 2.416123947936049, "Hair growth abnormal": 2.4903221734512666, "Hepatic enzyme abnormal": 2.5006086668954843, "Hepatic failure": 3.2574929478178287, "Hepatic lesion": 8.231980579726653, "Hepatic neoplasm": 12.642163649696869, "Hip fracture": 2.179901295720906, "Hot flush": 5.226743430294895, "Hydrocephalus": 2.2539506872382327, "Hydronephrosis": 2.796452111200169, "Hypercalcaemia": 2.268550552941494, "Induration": 5.236855850015062, "Injection site abscess": 5.592909031300689, "Injection site bruising": 4.191793420797693, "Injection site cellulitis": 11.167714170738469, "Injection site cyst": 71.50813924713485, "Injection site discomfort": 7.942795958596692, "Injection site extravasation": 4.765632015180158, "Injection site haematoma": 2.805901824263979, "Injection site haemorrhage": 2.9686186307671503, "Injection site hypersensitivity": 4.179953648659973, "Injection site hypoaesthesia": 7.181490005548178, "Injection site induration": 7.819264698100782, "Injection site infection": 9.307755579827322, "Injection site injury": 23.01710109648364, "Injection site irritation": 8.656815300448518, "Injection site mass": 19.18460041908295, "Injection site necrosis": 26.261967838161603, "Injection site nodule": 20.345701460816827, "Injection site pain": 2.0177097089284426, "Injection site pruritus": 2.517106273189357, "Injection site rash": 3.834330821313552, "Injection site ulcer": 62.724824249174034, "Injection site urticaria": 2.0478226290609745, "Injection site vesicles": 5.038075880186328, "Interstitial lung disease": 2.643947216430054, "Intestinal metastasis": 31.54858814547517, "Invasive ductal breast carcinoma": 3.5074992033801062, "Iron deficiency anaemia": 2.581671835801861, "KL-6 increased": 11.426985206418728, "Laboratory test abnormal": 2.0643361529181057, "Lacrimation increased": 2.7616587199885285, "Laryngospasm": 5.708060538392148, "Leukopenia": 2.536261389299558, "Limb mass": 4.802251280962516, "Lymphadenopathy mediastinal": 10.970817977116202, "Lymphangiosis carcinomatosa": 19.843535959797293, "Lymphoedema": 9.579064640082343, "Madarosis": 6.604788663140464, "Malignant neoplasm progression": 17.997986828207942, "Malignant pleural effusion": 20.49427772318037, "Mass": 3.613092717923352, "Menopause": 7.282248005737272, "Metastases to adrenals": 7.958295671219209, "Metastases to bone": 58.58671178279609, "Metastases to bone marrow": 21.753073065422253, "Metastases to breast": 42.91316863547268, "Metastases to central nervous system": 8.37805200645075, "Metastases to eye": 43.01452755606432, "Metastases to liver": 28.087636815661828, "Metastases to lung": 21.256895619078485, "Metastases to lymph nodes": 22.12534499300405, "Metastases to meninges": 5.702916057930128, "Metastases to ovary": 42.62108703170514, "Metastases to pelvis": 28.673534712106964, "Metastases to peritoneum": 14.680872262805131, "Metastases to pleura": 29.29441394990671, "Metastases to retroperitoneum": 46.87333645376855, "Metastases to skin": 49.9831245725674, "Metastases to spine": 31.36614352824106, "Metastasis": 21.73320604899034, "Metastatic neoplasm": 9.00727358121581, "Micturition urgency": 2.025270188398489, "Muscle disorder": 2.2124704111162545, "Musculoskeletal chest pain": 3.36273346332334, "Musculoskeletal pain": 3.3305322488135696, "Neoplasm malignant": 2.303225593522336, "Neoplasm progression": 18.54235192038265, "Neoplasm recurrence": 12.949196903280855, "Nerve injury": 2.979615705217792, "Neuropathy peripheral": 3.2770248616790814, "Neutropenia": 6.2965034591538265, "Neutrophil count decreased": 5.533064601188822, "Nodule": 2.319805556738525, "Oestradiol increased": 47.44030446759679, "Onychoclasis": 10.254229166778646, "Onycholysis": 13.872443811895666, "Osteonecrosis of jaw": 5.799410801779114, "Pathological fracture": 4.183700382275155, "Peripheral artery thrombosis": 6.61675890822374, "Platelet count decreased": 2.9418865320759053, "Pleural effusion": 4.80355614891473, "Product administered at inappropriate site": 2.782236681630487, "Pulmonary embolism": 2.0970138965659317, "Pulmonary mass": 2.8399964324246088, "Recurrent cancer": 12.050339317952336, "Red blood cell count decreased": 4.756003783202669, "Retinal vein occlusion": 2.071914513698653, "Sciatic nerve injury": 17.580402697143196, "Sciatica": 13.594553438163487, "Second primary malignancy": 3.716338760678712, "Skin mass": 2.422340461629647, "Skin odour abnormal": 4.505077567485986, "Small intestinal obstruction": 2.0936996016950724, "Stomatitis": 2.45323353843772, "Terminal state": 3.129734785968298, "Throat tightness": 2.2270664953019548, "Thyroid mass": 3.2997800438943083, "Tooth disorder": 2.627146396646338, "Tooth infection": 4.250484826129025, "Trigger finger": 6.557475977970399, "Tumour flare": 39.262447548276285, "Tumour marker abnormal": 58.22577495888871, "Tumour marker increased": 110.9066845384365, "Urine odour abnormal": 9.471749725649746, "Uterine cancer": 2.462324573735119, "Vulvovaginal dryness": 11.455074088722212, "Weight fluctuation": 3.557521024005386, "White blood cell count abnormal": 3.0723644565710497, "White blood cell count decreased": 5.90709554467867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/467.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/467.json
index 8e8d77f9d46..da8690b183d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/467.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/467.json
@@ -1 +1 @@
-{"Clostridium difficile colitis ": 52.24160712664252, "Clostridium difficile infection ": 919.7556850050524, "Diarrhoea ": 2.630815024727764, "Disease recurrence ": 21.4153122058721, "Drug ineffective ": 5.002926254665314, "Drug interaction ": 3.104742663126507, "Drug resistance ": 16.348234021143536, "Septic shock ": 15.916624274892069, "Treatment failure ": 21.178076018884656}
\ No newline at end of file
+{"Anaphylactic reaction": 5.5744957362280125, "Anaphylactic shock": 16.892588066902487, "Blood bilirubin increased": 9.020605055814965, "Blood pressure decreased": 3.5456705675009723, "Blood uric acid increased": 59.56608188824778, "Bronchospasm": 34.28335993372861, "Erythema": 2.8807346571103527, "Glucose-6-phosphate dehydrogenase deficiency": 995.870006735314, "Haemolysis": 127.16543489514792, "Haemolytic anaemia": 158.64867509702987, "Hepatic cytolysis": 13.067967373960176, "Hyperhidrosis": 2.6947521239337107, "Hypersensitivity": 5.776898181662395, "Hypertriglyceridaemia": 56.7835595759765, "Hypotension": 4.933211856002712, "Methaemoglobinaemia": 2326.180366476596, "Oxygen saturation decreased": 11.493837231483662, "Respiratory failure": 5.107167888920843, "Thrombocytopenia": 2.263643006830208, "Tumour lysis syndrome": 52.99487645992284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/468.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/468.json
index 8937e0abaae..1e016214592 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/468.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/468.json
@@ -1 +1 @@
-{"Acute febrile neutrophilic dermatosis ": 49.66079651931088, "Acute myeloid leukaemia ": 14.557095345878752, "Acute myeloid leukaemia recurrent ": 24.1706337116965, "Acute respiratory distress syndrome ": 5.646135107770378, "Acute respiratory failure ": 4.631085458461365, "Adenovirus infection ": 14.02168012438511, "Agranulocytosis ": 6.656439416068348, "Anaemia ": 2.4492796982352885, "Aortitis ": 124.04884208021328, "Bacterial infection ": 5.667570815093459, "Blood lactate dehydrogenase increased ": 2.6534633858601646, "Blood magnesium decreased ": 14.911725946718452, "Blood test abnormal ": 5.862678694532354, "Bone marrow failure ": 9.8705142543334, "Bone pain ": 13.280394044322543, "Brain oedema ": 3.664707415618436, "Bronchopulmonary aspergillosis ": 10.11119033701555, "Capillary leak syndrome ": 33.26666426524781, "Catheter site infection ": 25.24170152175138, "Clostridium difficile infection ": 9.345076437717816, "Coagulopathy ": 2.1561617411715326, "Cytopenia ": 13.273573849627804, "Disease progression ": 5.691044539623913, "Drug exposure before pregnancy ": 323.0463228627666, "Drug ineffective for unapproved indication ": 5.033851958869401, "Enteritis ": 11.024011570548574, "Febrile neutropenia ": 35.835060872544766, "Fungal infection ": 2.776055475040984, "Graft versus host disease ": 14.274505669524556, "Haemophagocytic lymphohistiocytosis ": 12.59214449028324, "Haemoptysis ": 2.3648124959167345, "Heart rate abnormal ": 11.977554611581343, "Hepatotoxicity ": 4.74742296262051, "Hydronephrosis ": 10.957984356054409, "Hypoalbuminaemia ": 10.094315017292956, "Hypocalcaemia ": 3.3445146855594885, "Hypogammaglobulinaemia ": 18.21006282910948, "Hypokalaemia ": 2.629480043611476, "Hypomagnesaemia ": 11.471376767103354, "Hypophosphataemia ": 6.124584341366077, "Hypoxia ": 3.470708117776895, "Ill-defined disorder ": 4.718735223307243, "Immune reconstitution inflammatory syndrome ": 17.22886813102781, "Immunodeficiency ": 4.148600935072378, "Infection ": 4.540561875374493, "Infusion site erythema ": 13.037577282455592, "Infusion site swelling ": 18.66190562131812, "Leukocytosis ": 8.284765185677102, "Leukopenia ": 3.9119765681220486, "Lung disorder ": 2.136088260073278, "Lymphadenitis ": 6.142341843596005, "Meningitis tuberculous ": 94.97647903946046, "Metastases to liver ": 2.8805693342087046, "Metastases to lung ": 3.06413385708991, "Metastases to lymph nodes ": 5.741533166035016, "Mouth ulceration ": 4.5161053343012325, "Mucosal inflammation ": 12.74216972681663, "Multiple organ dysfunction syndrome ": 5.779657534825653, "Muscle twitching ": 2.3890805251928344, "Myelodysplastic syndrome ": 13.501437347217127, "Neoplasm progression ": 4.055131988845357, "Nervous system disorder ": 2.3308717899712668, "Neuropathy peripheral ": 3.150272808188062, "Neurotoxicity ": 4.538518941240761, "Neutropenia ": 8.73692701372425, "Neutropenic sepsis ": 19.917272888526316, "Neutrophil count decreased ": 2.8221663869961584, "Neutrophil count increased ": 13.52660983739053, "Neutrophilia ": 17.766347641778545, "Off label use ": 3.128737067711662, "Pancytopenia ": 3.626621420261626, "Pericardial effusion ": 2.1902240367957204, "Plasma cell myeloma ": 2.186982839596736, "Platelet count decreased ": 3.1915693329160493, "Pleural effusion ": 2.5036895903331797, "Pneumonitis ": 4.767284495053123, "Product use in unapproved indication ": 2.904038044521989, "Productive cough ": 2.0603241596788977, "Progressive multifocal leukoencephalopathy ": 15.817642690554772, "Respiratory failure ": 2.048005719132473, "Sepsis ": 4.1493828570764935, "Septic shock ": 2.58453074251702, "Skin lesion ": 2.3315305593421614, "Skin toxicity ": 7.554563587363239, "Splenic rupture ": 32.08687973890925, "Staphylococcal bacteraemia ": 43.407933374971314, "Staphylococcal infection ": 2.398277542913114, "Tachypnoea ": 2.245706652746456, "Therapy non-responder ": 7.107143970973526, "Therapy partial responder ": 13.53813885111127, "Thrombocytopenia ": 3.8939351499239487, "Toxic epidermal necrolysis ": 2.8568773211861616, "Treatment failure ": 2.052303375484998, "Ureteric obstruction ": 64.22892884661363, "Vasculitis ": 2.6227559250273336, "Venoocclusive liver disease ": 7.766363574614862, "Viral infection ": 4.9977116655340055, "White blood cell count decreased ": 3.775530833965232, "White blood cell count increased ": 6.608190500451387}
\ No newline at end of file
+{"Acute hepatic failure": 7.108204797090248, "Acute kidney injury": 4.005754327398509, "Acute myocardial infarction": 21.613647337196824, "Angina pectoris": 3.3446336817222884, "Blood creatine phosphokinase increased": 3.293127864291897, "Blood creatinine increased": 2.9787129082923007, "Blood urea increased": 3.647447341047908, "Blood uric acid increased": 10.315619217620414, "Cardiac failure": 4.2678107157369904, "Cardiac failure congestive": 5.466937157073958, "Cellulitis": 2.1137575478070527, "Cerebrovascular accident": 2.75915107214427, "Coronary artery disease": 8.957164346603985, "Drug eruption": 8.88118744589666, "Drug interaction": 3.087663455570989, "Drug reaction with eosinophilia and systemic symptoms": 5.734654195525256, "Drug-induced liver injury": 16.8997441458705, "Eosinophilia": 3.658325672210787, "Gout": 90.03909919508094, "Hepatic enzyme increased": 2.880551215072052, "Hepatic failure": 3.566373352290183, "Hepatic function abnormal": 10.761300746992374, "Hepatitis acute": 11.846524798139164, "Hyperkalaemia": 3.006060372077924, "Hypersensitivity vasculitis": 37.9628319273163, "Jaundice": 2.659373579356497, "Liver disorder": 6.650367268911463, "Liver function test abnormal": 6.175604854779799, "Liver injury": 5.979765053244534, "Lung neoplasm malignant": 3.855896899204271, "Melaena": 2.2259922280989537, "Myocardial infarction": 5.898233011785821, "Nephrolithiasis": 3.4735292273318694, "Oedema peripheral": 2.0152766814963923, "Pancytopenia": 5.428976435862894, "Platelet count decreased": 2.8055667966060978, "Prescribed underdose": 8.9209062405223, "Procedural haemorrhage": 48.5525773713977, "Pulmonary haemorrhage": 15.529225430457023, "Rash": 2.7367341733229, "Rash maculo-papular": 2.8490280836336064, "Renal failure": 2.870292419130249, "Renal impairment": 5.16916590349279, "Renal tubular necrosis": 12.729132856234658, "Rhabdomyolysis": 13.469588248387131, "Sepsis": 2.1847203135731004, "Stevens-Johnson syndrome": 11.081747040054172, "Thrombocytopenia": 2.1734366575890243, "Toxic epidermal necrolysis": 6.188260503623746, "Transaminases increased": 2.3424457590742263, "Tubulointerstitial nephritis": 8.222750106862218, "Underdose": 4.828899641593568, "Wrong technique in product usage process": 2.6376589170415925}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/469.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/469.json
index 0abef1179c9..e288e5ae1e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/469.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/469.json
@@ -1 +1 @@
-{"Electrocardiogram T wave inversion ": 419.3855741897945, "Multiple sclerosis relapse ": 43.94406459061196}
\ No newline at end of file
+{"Therapy non-responder": 36.52182079928677, "Vaccination site pain": 4.011770971260221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/47.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/47.json
index 5273ac81725..e06e340dec7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/47.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/47.json
@@ -1 +1 @@
-{"Acquired haemophilia ": 19.142103368940788, "Acute graft versus host disease ": 62.7659728197267, "Acute graft versus host disease in intestine ": 74.40462534909389, "Acute graft versus host disease in liver ": 24.44637553113779, "Acute graft versus host disease in skin ": 31.71298872039715, "Acute myeloid leukaemia recurrent ": 8.578952651329592, "Acute respiratory distress syndrome ": 3.17974527033292, "Adenovirus infection ": 181.3710850576448, "Anti-thyroid antibody positive ": 24.57803533114699, "Aplasia pure red cell ": 9.825559097273809, "Aplastic anaemia ": 23.593529507529723, "Aspergillus infection ": 15.192759030826885, "Autoimmune haemolytic anaemia ": 54.66889530640226, "Autoimmune hypothyroidism ": 50.54028524505242, "Autoimmune thyroiditis ": 15.36116696269174, "BK virus infection ": 72.44399289206207, "Bacteraemia ": 11.823711518616143, "Bacterial infection ": 2.1116822650164377, "Bacterial sepsis ": 18.61122825673286, "Bacterial test ": 95.23203747798289, "Bacterial test positive ": 35.25162962343912, "Blood stem cell transplant failure ": 186.24789616974712, "Blood thyroid stimulating hormone decreased ": 15.298033765541591, "Blood thyroid stimulating hormone increased ": 3.1351899913100523, "Blood urine present ": 10.536571524487783, "Bone marrow failure ": 3.599763130981557, "Bone marrow transplant rejection ": 59.13026142906176, "Bronchiolitis obliterans syndrome ": 153.73646169965403, "Bronchopulmonary aspergillosis ": 17.595827731929738, "Candida infection ": 2.1130527141253905, "Central nervous system lesion ": 8.794277114750273, "Central nervous system lymphoma ": 24.31886633760292, "Cerebral aspergillosis ": 86.48771128702572, "Chronic graft versus host disease ": 23.88828271556361, "Chronic graft versus host disease in liver ": 58.221015752229405, "Chronic graft versus host disease in skin ": 84.82905826222768, "Chronic lymphocytic leukaemia ": 7.409467667290668, "Clostridium difficile infection ": 5.1170895895187405, "Complications of bone marrow transplant ": 85.14854147169456, "Coronavirus infection ": 6.08571060657496, "Crystal urine present ": 149.01850558435518, "Cutibacterium acnes infection ": 165.522126255569, "Cystitis haemorrhagic ": 9.668588880133129, "Cystitis viral ": 77.784604009242, "Cytomegalovirus chorioretinitis ": 16.31098753697818, "Cytomegalovirus infection ": 49.749617055749, "Cytomegalovirus infection reactivation ": 123.14195675160046, "Cytomegalovirus viraemia ": 70.69391237765147, "Cytopenia ": 5.205078316545678, "Device related infection ": 2.451565360099706, "Diarrhoea haemorrhagic ": 2.96144904830488, "Diarrhoea infectious ": 32.928132622496214, "Diffuse large B-cell lymphoma ": 15.042745800948628, "Diplopia ": 2.3841301015843754, "Disability ": 2.2511499766809986, "Disseminated Bacillus Calmette-Guerin infection ": 95.58470525823957, "Disseminated tuberculosis ": 21.420462696752278, "Drug exposure before pregnancy ": 16.82372605027741, "Drug ineffective for unapproved indication ": 4.901909959900498, "Drug resistance ": 4.3984065013946, "Dry throat ": 4.159068227391758, "Encephalitis ": 3.5965050458968038, "Encephalitis viral ": 48.67129686049386, "End stage renal disease ": 18.0307891808845, "Endocrine ophthalmopathy ": 34.06964272326116, "Enteritis ": 9.87963793545645, "Enterobacter bacteraemia ": 131.083245861796, "Enterobacter infection ": 17.30393805754053, "Enterococcal bacteraemia ": 45.70661841003324, "Enterococcal infection ": 13.504357997265055, "Eosinophil count increased ": 5.139019804658902, "Epstein-Barr viraemia ": 135.55232041199235, "Epstein-Barr virus associated lymphoma ": 59.39847357271024, "Epstein-Barr virus associated lymphoproliferative disorder ": 29.32513532776924, "Epstein-Barr virus infection ": 40.770837514778975, "Epstein-Barr virus infection reactivation ": 46.879622719835815, "Escherichia bacteraemia ": 23.60937498931075, "Escherichia infection ": 7.273490341528614, "Escherichia urinary tract infection ": 15.179849052956891, "Exophthalmos ": 9.263510180266522, "Febrile neutropenia ": 4.413969588305796, "Flushing ": 2.7850268086262484, "Fungaemia ": 14.060997500515118, "Fungal infection ": 3.922881657236138, "Gastroenteritis ": 3.075669665353677, "Gastroenteritis adenovirus ": 189.560551622362, "Gastroenteritis norovirus ": 36.64665719727967, "Goitre ": 5.513325469285062, "Graft loss ": 67.08965016411776, "Graft versus host disease ": 40.33917729872454, "Graft versus host disease in gastrointestinal tract ": 32.958702216088405, "Graft versus host disease in skin ": 77.87851517315042, "Granuloma ": 10.468145625487544, "Graves' disease ": 48.07766711559017, "Grip strength decreased ": 2.982527248391108, "Haematocrit decreased ": 2.845809387099111, "Haemolytic anaemia ": 2.274984991949653, "Haemophagocytic lymphohistiocytosis ": 18.731535804325123, "Heart rate decreased ": 2.591183967688109, "Hemiparesis ": 2.2344852332545564, "Hepatitis B ": 14.717400918668078, "Hepatosplenomegaly ": 8.69857985981491, "Herpes simplex ": 50.22142242801687, "Herpes virus infection ": 2.474231961773608, "Herpes zoster disseminated ": 24.0122824094106, "Human herpesvirus 6 infection ": 123.29535663017454, "Human herpesvirus 6 infection reactivation ": 93.84321926661865, "Human polyomavirus infection ": 94.26560487904035, "Hydrocephalus ": 4.752369327297212, "Hyperthyroidism ": 7.394679872864422, "Hypertransaminasaemia ": 4.149325553018896, "Hypervolaemia ": 3.215750790250513, "Hypogammaglobulinaemia ": 13.786378272875783, "Immune reconstitution inflammatory syndrome ": 4.207156710514938, "Immune system disorder ": 3.223893880663861, "Immune thrombocytopenia ": 11.617157084676991, "Immunosuppression ": 8.447408302109308, "Increased appetite ": 2.082442139972103, "Increased tendency to bruise ": 3.2210497797976574, "Infection ": 3.1969882535044176, "Infusion site erythema ": 5.745024877636352, "Infusion site extravasation ": 18.968352798601163, "Infusion site pain ": 5.901168180737076, "Iron overload ": 25.589993467539543, "JC virus infection ": 87.05177335830737, "Kidney transplant rejection ": 14.16225761455937, "Klebsiella bacteraemia ": 47.38951551940746, "Klebsiella infection ": 8.117481577300529, "Klebsiella sepsis ": 17.566062512342242, "Leukaemia recurrent ": 22.67287098012612, "Listeriosis ": 45.08557899441609, "Lung infiltration ": 3.77877024318674, "Lymphocyte count decreased ": 27.1582447485189, "Lymphocyte percentage decreased ": 48.71873892507818, "Lymphopenia ": 23.22435633524737, "Lymphoproliferative disorder ": 71.89894350936628, "Magnetic resonance imaging abnormal ": 33.4308022293989, "Mean cell haemoglobin decreased ": 44.057680901303655, "Meningitis tuberculous ": 85.5928231358192, "Meningitis viral ": 19.08377803895416, "Microsporidia infection ": 265.35095102493494, "Monocyte count decreased ": 21.62742227465071, "Monocyte percentage increased ": 86.31492287084673, "Mucormycosis ": 10.685504653851993, "Mucosal inflammation ": 22.0039540849673, "Multiple organ dysfunction syndrome ": 9.396115394781216, "Multiple sclerosis ": 3.0084014570127406, "Multiple sclerosis relapse ": 14.41758214973277, "Mycobacterium kansasii infection ": 121.30209803279804, "Nephropathy toxic ": 2.191080728615165, "Neutropenia ": 2.770013540322416, "Neutrophil count increased ": 4.250546417397724, "Neutrophil percentage increased ": 27.769461020411832, "Nitrite urine present ": 97.54135168891756, "Nocardiosis ": 17.762404934025476, "Norovirus infection ": 72.61635787511798, "Nystagmus ": 2.6019176531375776, "Odynophagia ": 5.735476573627094, "Off label use ": 4.53368741691868, "Optic neuritis ": 3.10922594352912, "Oral herpes ": 2.250134324863444, "Organising pneumonia ": 4.291803685718118, "Pancytopenia ": 5.134437082651225, "Parainfluenzae virus infection ": 16.16767691459181, "Paresis ": 3.688983128231283, "Paronychia ": 8.34648148828121, "Pathogen resistance ": 14.311673228735405, "Pericardial effusion ": 2.9760253923020445, "Pneumocystis jirovecii pneumonia ": 10.72556943342062, "Pneumonia adenoviral ": 333.0077595131308, "Pneumonia cytomegaloviral ": 66.76792862072492, "Pneumonia respiratory syncytial viral ": 28.485077342419917, "Pneumonitis ": 5.265153621638745, "Polyomavirus viraemia ": 138.43621350133128, "Post transplant lymphoproliferative disorder ": 85.15263786883847, "Posterior reversible encephalopathy syndrome ": 5.29562500507369, "Product use in unapproved indication ": 4.414279218738303, "Progressive multifocal leukoencephalopathy ": 58.48425720886843, "Pseudomonal sepsis ": 14.667354594778637, "Pseudomonas infection ": 15.67225481119778, "Pulmonary alveolar haemorrhage ": 6.253437234597988, "Pulmonary haemorrhage ": 9.235347963653105, "Red blood cells urine positive ": 46.69188677116886, "Red cell distribution width increased ": 8.389569900968965, "Respiratory disorder ": 3.144984331877096, "Respiratory failure ": 3.969103482953472, "Respiratory syncytial virus infection ": 4.223329983070455, "Rhinovirus infection ": 7.300187238670862, "Richter's syndrome ": 34.21538925188337, "Sarcoidosis ": 3.3277434525972134, "Sepsis ": 5.11287239826322, "Septic shock ": 3.62869809447934, "Serum ferritin increased ": 3.024994164257086, "Sinus bradycardia ": 2.257763818856616, "Skin mass ": 3.74788859673578, "Staphylococcal bacteraemia ": 25.222769160984303, "Staphylococcal infection ": 4.960666192034022, "Stem cell transplant ": 24.66516696859416, "Systemic candida ": 11.10772666084696, "Therapeutic response decreased ": 2.1095828872050557, "Therapy partial responder ": 5.031594306155249, "Thrombotic microangiopathy ": 15.695086587954654, "Transplant dysfunction ": 23.97433169331449, "Transplant failure ": 111.03563885862272, "Transplant rejection ": 51.53554269419166, "Urinary sediment present ": 188.00131186300544, "Urinary tract infection bacterial ": 15.84611562356006, "Urine abnormality ": 25.74766403219155, "Urine analysis abnormal ": 10.254663385925566, "Urine ketone body present ": 19.65047433777163, "Varicella ": 2.6012099944001474, "Varicella zoster virus infection ": 32.53639145212722, "Vascular device infection ": 8.127834469277639, "Venoocclusive disease ": 64.02644450136266, "Venoocclusive liver disease ": 27.41478251505784, "Viraemia ": 102.06373233725432, "Viral haemorrhagic cystitis ": 25.892772364661948, "Viral infection ": 2.633146529383555, "White blood cells urine positive ": 37.20566405736726}
\ No newline at end of file
+{"Disease progression": 15.624291637905497, "Drug resistance": 24.23544654161696, "Malignant neoplasm progression": 15.476810263090869, "Maternal exposure during pregnancy": 9.549310742223993, "Metastases to central nervous system": 68.20092214816468, "Neoplasm progression": 20.30908897295376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/470.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/470.json
index 23bf7e96d47..b2eee6b7990 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/470.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/470.json
@@ -1 +1 @@
-{"Seizure ": 20.686666023072323}
\ No newline at end of file
+{"Abortion induced": 4.205399165786487, "Abscess neck": 20.64000328673334, "Accidental death": 6.420465065478012, "Accidental overdose": 7.296696509051243, "Acute hepatic failure": 2.4525371219519623, "Acute postoperative sialadenitis": 140.18640990988268, "Acute pulmonary oedema": 5.017621557197493, "Acute respiratory distress syndrome": 3.381867516793409, "Acute respiratory failure": 2.5672483009048106, "Agitation": 2.593688167995888, "Agoraphobia": 6.6257225996736535, "Air embolism": 25.081074095529964, "Airway complication of anaesthesia": 43.74026045613645, "Airway peak pressure increased": 104.3362260798244, "Alcohol poisoning": 9.244850216422348, "Allodynia": 11.034650496853224, "Amphetamines positive": 104.577100957766, "Anaesthetic complication": 17.949859931588605, "Anaesthetic complication neurological": 6.451099949958561, "Anaphylactic reaction": 8.237293411691851, "Anaphylactic shock": 5.617398759622583, "Anaphylactoid reaction": 7.427675002465234, "Anaphylactoid shock": 3.825028334502896, "Anisocoria": 8.321763422545263, "Anterior spinal artery syndrome": 103.38249280917366, "Anticholinergic syndrome": 8.214169926683484, "Anuria": 2.54843334382937, "Anxiety disorder": 3.0411759723014677, "Apgar score abnormal": 47.96208484926404, "Apgar score low": 48.84607459003578, "Apnoea": 14.500715243229545, "Apnoeic attack": 16.405934064100283, "Arachnoiditis": 14.479291842596162, "Areflexia": 6.639725212349458, "Arteriospasm coronary": 6.207012823058885, "Arthritis bacterial": 2.8711047605091102, "Asphyxia": 2.9110379010938736, "Atelectasis": 2.038049676812936, "Atrioventricular block complete": 4.971062134587513, "Atrioventricular block second degree": 6.249130685096789, "Autonomic dysreflexia": 49.39685163989798, "Autonomic nervous system imbalance": 4.744578589751511, "Bispectral index decreased": 231.17632356547304, "Blood albumin decreased": 2.2664768471674, "Blood ethanol": 1060.4484356138194, "Blood ethanol increased": 58.9575070863792, "Blood lactic 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7.789305022210832, "Infantile apnoea": 6.196889910937904, "Infusion site extravasation": 2.88855702159754, "Infusion site mass": 23.9480347347853, "Inspiratory capacity decreased": 193.36732750027576, "Intensive care unit acquired weakness": 56.56351118497405, "Intentional product misuse": 6.376195900955742, "Intentional underdose": 2.88586002354976, "Intestinal stenosis": 5.953257521455817, "Judgement impaired": 4.73366634236642, "Laryngeal obstruction": 26.97953953146387, "Laryngospasm": 11.343325950723226, "Learning disability": 14.239131217204893, "Lip ulceration": 5.348952480703394, "Live birth": 12.97421602606081, "Loss of consciousness": 2.1538125155834678, "Loss of employment": 5.285808410681556, "Low birth weight baby": 11.951621813832205, "Maternal exposure during delivery": 34.589107573576335, "Maternal exposure during pregnancy": 3.5388088680459973, "Maternal exposure timing unspecified": 8.416561639098669, "Mean arterial pressure decreased": 40.51701647152327, "Mechanical 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4.840864251104226, "Skin test positive": 3.6837232257327024, "Slow response to stimuli": 2.667539785489289, "Snoring": 5.774016831290838, "Somatic symptom disorder": 4.017871061175736, "Somnolence": 2.288365209571762, "Spinal cord compression": 2.838999899233055, "Spinal cord infarction": 36.173441129656666, "Spinal cord injury": 13.472696926987572, "Spinal cord oedema": 26.83124180552105, "Spinal epidural haematoma": 6.405061695887704, "Stereotypy": 7.881632216937925, "Stress cardiomyopathy": 13.255410247235424, "Stridor": 3.087816057246131, "Stupor": 2.545391183522616, "Substance abuse": 22.11762750065504, "Substance dependence": 51.43757104133166, "Substance use disorder": 10.905775720800218, "Supraventricular tachycardia": 2.354020718875351, "Suspected suicide": 3.9280592425224503, "Tachycardia": 2.392833928305333, "Tachycardia foetal": 11.790156404907377, "Therapeutic product effect increased": 3.1677416803901792, "Thyrotoxic crisis": 4.650816953229605, "Torsade de pointes": 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in product usage process": 2.1596142784655523, "X-ray abnormal": 5.7910802021429415}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/471.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/471.json
index a0b9265a816..b460d36f6e1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/471.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/471.json
@@ -1 +1 @@
-{"Drug ineffective ": 3.552018041754844, "Hereditary angioedema ": 243.83730034031265}
\ No newline at end of file
+{"Amnesia": 32.82498513043153, "Aphasia": 49.54106005035204, "Bradycardia": 20.25370931579716, "Brain injury": 172.84067716290758, "Cardiac arrest": 14.19815081421435, "Cardiomegaly": 78.21093456841346, "Cerebral infarction": 51.30963731475755, "Cerebrovascular accident": 12.30017568805258, "Drug effect less than expected": 154.80469089025684, "Drug ineffective": 2.2527169204285, "Dry mouth": 8.070593073087295, "Dysstasia": 16.54920250090912, "Electrocardiogram QRS complex prolonged": 339.64979337597475, "Fall": 3.31713367393828, "Fracture": 14.77680835255884, "Hypotension": 7.466435803672097, "Loss of consciousness": 25.64004190862393, "Muscle spasms": 3.0627913244552927, "Off label use": 2.128414002796393, "Overdose": 31.18354674290772, "Product use in unapproved indication": 2.267321273012227, "Product use issue": 11.161460207839356, "Pulseless electrical activity": 1101.004184712733, "Syncope": 2.2169843195850305, "Tendon disorder": 61.27244894001729, "Transient ischaemic attack": 51.72925328426641, "Urinary incontinence": 19.09595546932221, "Vertigo": 3.2623678498331685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/472.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/472.json
index 9cccc0e7b42..238bd011407 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/472.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/472.json
@@ -1 +1 @@
-{"Abdominal pain upper ": 2.1604485574137917, "Acute respiratory failure ": 5.756416375761702, "Anosmia ": 2.156678766324315, "Aphasia ": 2.173363708595058, "Aspiration ": 4.75929026938899, "Asthenia ": 2.80691589135434, "Atelectasis ": 3.7577919151614183, "Atrial fibrillation ": 2.549596115594594, "Autoimmune disorder ": 2.866852161161946, "Back disorder ": 3.96975168885958, "Bacteraemia ": 3.888690093487265, "Balance disorder ": 3.278938069832794, "Blood magnesium decreased ": 9.202451250214928, "Blood potassium decreased ": 6.30595620601347, "Blood sodium decreased ": 4.26185594098968, "COVID-19 pneumonia ": 2.835437323855892, "Central venous catheterisation ": 34.560489657803785, "Choking ": 2.9498612247891223, "Concussion ": 8.9172810656474, "Condition aggravated ": 2.3767478608863386, "Dehydration ": 2.9407898179763907, "Diplopia ": 6.9382630421549285, "Diverticulitis ": 3.7990582536834814, "Dysphagia ": 3.64168044297242, "Eye movement disorder ": 5.286820300412947, "Failure to thrive ": 11.745868033030764, "Fall ": 5.475346307178032, "Fear ": 2.305000881015459, "Feeding disorder ": 3.548973781086381, "Feeling abnormal ": 2.816316161144514, "Feeling cold ": 2.938477271034456, "Foot fracture ": 2.887743426747204, "Gait disturbance ": 4.109778868059983, "Gait inability ": 3.0748778697231858, "Gastric ulcer haemorrhage ": 8.53966430168686, "Gastroenteritis ": 4.008595158741052, "Haemorrhoids ": 2.041104762101816, "Head injury ": 3.303139302154598, "Hospice care ": 31.54554206505523, "Hospitalisation ": 2.305664361436756, "Hypersomnia ": 5.087513095724264, "Hypervolaemia ": 4.827315829800914, "Hypoaesthesia oral ": 12.427589323305709, "Hypomagnesaemia ": 6.584150088676262, "Hypophagia ": 6.011332075825327, "Hypophosphataemia ": 5.68891863279898, "Hypoxia ": 2.549474865649298, "Inflammation ": 2.0597810317065632, "Intentional product use issue ": 4.69041585991112, "Intestinal obstruction ": 2.586779812852288, "Joint injury ": 3.9161525349876736, "Leukocytosis ": 3.2988755388621627, "Lung neoplasm malignant ": 2.565299176101854, "Malnutrition ": 11.32959981765502, "Mobility decreased ": 2.464524274103693, "Motor dysfunction ": 3.8288868154505455, "Muscle spasms ": 2.497313669035319, "Muscular weakness ": 5.637877128661003, "Musculoskeletal chest pain ": 3.727798313730399, "Myasthenia gravis ": 6.813466680856688, "Myasthenic syndrome ": 594.6413670970958, "Nephrolithiasis ": 3.365137644866734, "Nervousness ": 2.1004215225844822, "Paraesthesia ": 2.8597808828072098, "Paraesthesia oral ": 15.399609317702334, "Performance status decreased ": 7.632333974926924, "Peripheral coldness ": 5.685801884561881, "Pneumonia ": 2.3820300020231087, "Pneumonia aspiration ": 2.8363868391695477, "Pneumothorax ": 5.778507363024353, "Post procedural haemorrhage ": 4.867379872549266, "Prescribed overdose ": 5.580106995554496, "Product dose omission issue ": 6.084423135177395, "Product substitution issue ": 7.632033296057564, "Psychomotor hyperactivity ": 2.2369151359801256, "Pulmonary fibrosis ": 3.287769988996234, "Pulmonary mass ": 7.148871893842365, "Respiratory failure ": 2.0040752809602957, "Restless legs syndrome ": 2.5400433727668816, "Rib fracture ": 10.17001388322952, "Sinus tachycardia ": 2.104927642603102, "Small cell lung cancer ": 56.72582272075472, "Small cell lung cancer recurrent ": 763.5603741761499, "Speech disorder ": 3.0044186285394074, "Supraventricular tachycardia ": 3.159163250369585, "Therapeutic product effect incomplete ": 5.672589215228185, "Therapeutic response delayed ": 85.94966454681091, "Therapeutic response shortened ": 64.89857066725571, "Therapy interrupted ": 7.525964569882879, "Torticollis ": 12.4754585950007, "Ulcer haemorrhage ": 5.150840792644057, "Unevaluable event ": 16.06641990265106, "Urinary tract infection ": 3.2972756571537345, "Ventricular extrasystoles ": 3.630375204402277, "Viral infection ": 4.3644019595714205, "Walking aid user ": 10.844775682483965, "Weight decreased ": 2.169741021286349, "Wheelchair user ": 12.285128043700904, "Wound haemorrhage ": 12.983648366956718, "Wound infection ": 7.93707873892532, "Wrist fracture ": 3.720009960551506}
\ No newline at end of file
+{"Accidental overdose": 2.3073072133805352, "Blood glucose abnormal": 48.14319129116627, "Blood glucose decreased": 18.596151662033535, "Blood glucose fluctuation": 67.70944219940554, "Blood glucose increased": 51.12895036994917, "Dermatitis allergic": 2.431455136177823, "Device breakage": 56.746735137242574, "Device defective": 27.11253687493741, "Device delivery system issue": 28.734911725280774, "Device failure": 51.76459076685835, "Device information output issue": 326.8879385087757, "Device issue": 27.175116472167836, "Device leakage": 14.105993215069086, "Device malfunction": 16.337244159132315, "Device occlusion": 26.088542357191265, "Diabetes mellitus inadequate control": 16.217478184626113, "Diabetic ketoacidosis": 14.355386403881882, "Diabetic metabolic decompensation": 34.554959276089555, "Drug delivery system issue": 77.41934660973901, "Drug ineffective": 5.728378286860838, "Exposure during pregnancy": 3.107766577711557, "Extra dose administered": 13.375735541752793, "Glycosylated haemoglobin increased": 7.969175260571077, "Hyperglycaemia": 40.07916029064504, "Hypoglycaemia": 24.232409693831265, "Hypoglycaemic unconsciousness": 20.90015912959503, "Incorrect dose administered": 2.7532236557843843, "Incorrect dose administered by device": 86.37597565844638, "Increased insulin requirement": 353.33082829694865, "Infusion site erythema": 41.24580207192502, "Infusion site inflammation": 117.93992238579548, "Infusion site pain": 120.90463252864572, "Infusion site pruritus": 48.42270193240421, "Injection site atrophy": 58.28044840631933, "Injection site bruising": 8.970280605012752, "Injection site hypersensitivity": 18.08824697358781, "Injection site irritation": 40.72858039073311, "Injection site mass": 9.34902879851446, "Injection site pruritus": 3.2227400204039616, "Injection site rash": 5.843773635635211, "Insulin resistance": 56.15959659715353, "Ketoacidosis": 5.852942784178761, "Lipodystrophy acquired": 9.92302377284063, "Liquid product physical issue": 420.3053508253225, "Maternal exposure during pregnancy": 3.715952047276833, "Pain of skin": 2.566530920164422, "Product appearance confusion": 483.9761109908679, "Product colour issue": 60.53769089424682, "Product deposit": 192.4916176253385, "Product dispensing error": 4.509962676687867, "Product gel formation": 1915.7086965212984, "Product leakage": 30.90345513046058, "Product physical issue": 58.55406250142136, "Product quality issue": 29.729915004614316, "Product storage error": 16.45194331081482, "Therapeutic product effect decreased": 10.71812821943636, "Therapeutic product effect delayed": 150.43406455873426, "Therapeutic product effect variable": 53.105618289336135, "Thirst": 4.1500756402321, "Weight increased": 2.701589509299375, "Wrong product administered": 48.503592920981546, "Wrong technique in device usage process": 9.870899817844604, "Wrong technique in product usage process": 6.767579986124002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/473.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/473.json
index cc726480e86..ffe3d9422eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/473.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/473.json
@@ -1 +1 @@
-{"Anaphylactic reaction ": 3.992229157308128, "Anaphylactoid reaction ": 6.163378161538409, "Back pain ": 9.682999541249233, "Blood pressure decreased ": 3.4154665363280765, "Blood pressure increased ": 4.145427132656208, "Blood pressure systolic increased ": 4.886957626310301, "Body temperature increased ": 6.951221013208412, "Bronchospasm ": 6.6132311800444725, "Chest discomfort ": 3.878466862624317, "Chest pain ": 3.2907454108623195, "Chills ": 7.4501868887181635, "Cold sweat ": 2.134677419133161, "Cyanosis ": 11.46729900976664, "Dyspnoea ": 3.295519088789113, "Erythema ": 2.190214449810465, "Feeling cold ": 8.577465019364762, "Feeling hot ": 2.224037535126375, "Flank pain ": 6.981764310056512, "Flushing ": 10.991342307963158, "Haemolysis ": 5.9061059658649, "Heart rate increased ": 3.4979186956850405, "Hyperhidrosis ": 2.280769236112001, "Hypersensitivity ": 3.344426321589622, "Hypertension ": 7.321868578646285, "Hyperthermia ": 18.2845897031136, "Hypotension ": 5.378719871031152, "Hypothermia ": 3.83884042865582, "Hypoxia ": 7.254197857739967, "Infusion related reaction ": 14.098299361186882, "Livedo reticularis ": 24.941787286090964, "Meningitis aseptic ": 110.00785822130943, "Oxygen saturation decreased ": 17.462511487671325, "Pallor ": 6.844024464594878, "Photophobia ": 4.520758543111221, "Pyrexia ": 2.18280722246917, "Rash macular ": 2.8194846157169127, "Rash papular ": 2.0134069518047712, "Respiratory distress ": 4.014462704988785, "Respiratory rate increased ": 40.62222287428656, "Spinal pain ": 5.6353014240831865, "Tachycardia ": 7.8386890388498625, "Tachypnoea ": 20.042849176092307, "Throat tightness ": 2.4527997892165545, "Transfusion-related acute lung injury ": 132.70451860679563, "Tremor ": 5.859834203035443, "Urticaria ": 2.232238117157256, "Vomiting ": 2.259760608474346, "Wheezing ": 3.5015311649235485}
\ No newline at end of file
+{"Clostridium difficile colitis": 52.24160712664252, "Clostridium difficile infection": 919.7556850050524, "Diarrhoea": 2.6307930699003634, "Disease recurrence": 21.4153122058721, "Drug ineffective": 5.002889269810323, "Drug interaction": 3.104742663126507, "Drug resistance": 16.348234021143536, "Septic shock": 15.916624274892069, "Treatment failure": 21.178076018884656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/474.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/474.json
index 0073fada610..f0dfc93f67c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/474.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/474.json
@@ -1 +1 @@
-{"Adverse event ": 164.5255632399122, "Keratopathy ": 8587.701475032678, "Off label use ": 13.845086302562263, "Platelet count decreased ": 52.41792579823187, "Thrombocytopenia ": 33.06838792676811, "Visual acuity reduced ": 336.0945697421141}
\ No newline at end of file
+{"Acute febrile neutrophilic dermatosis": 49.66079651931088, "Acute myeloid leukaemia": 14.557095345878752, "Acute myeloid leukaemia recurrent": 24.1706337116965, "Acute respiratory distress syndrome": 5.646135107770378, "Acute respiratory failure": 4.631085458461365, "Adenovirus infection": 14.02168012438511, "Agranulocytosis": 6.656439416068348, "Anaemia": 2.4492796982352885, "Aortitis": 124.04884208021328, "Bacterial infection": 5.667570815093459, "Blood lactate dehydrogenase increased": 2.6534633858601646, "Blood magnesium decreased": 14.911725946718452, "Blood test abnormal": 5.862678694532354, "Bone marrow failure": 9.8705142543334, "Bone pain": 13.280394044322543, "Brain oedema": 3.664707415618436, "Bronchopulmonary aspergillosis": 10.11119033701555, "Capillary leak syndrome": 33.26666426524781, "Catheter site infection": 25.24170152175138, "Clostridium difficile infection": 9.345076437717816, "Coagulopathy": 2.1561617411715326, "Cytopenia": 13.262973101743931, "Disease progression": 5.691044539623913, "Drug exposure before pregnancy": 323.0463228627666, "Drug ineffective for unapproved indication": 5.033851958869401, "Enteritis": 11.024011570548574, "Febrile neutropenia": 35.835060872544766, "Fungal infection": 2.775285032924556, "Graft versus host disease": 14.274505669524556, "Haemophagocytic lymphohistiocytosis": 12.59214449028324, "Haemoptysis": 2.3648124959167345, "Heart rate abnormal": 11.977554611581343, "Hepatotoxicity": 4.74742296262051, "Hydronephrosis": 10.957984356054409, "Hypoalbuminaemia": 10.094315017292956, "Hypocalcaemia": 3.3445146855594885, "Hypogammaglobulinaemia": 18.21006282910948, "Hypokalaemia": 2.629480043611476, "Hypomagnesaemia": 11.471376767103354, "Hypophosphataemia": 6.124584341366077, "Hypoxia": 3.470708117776895, "Ill-defined disorder": 4.718735223307243, "Immune reconstitution inflammatory syndrome": 17.22886813102781, "Immunodeficiency": 4.148600935072378, "Infection": 4.540561875374493, "Infusion site erythema": 13.037577282455592, "Infusion site swelling": 18.66190562131812, "Leukocytosis": 8.284765185677102, "Leukopenia": 3.911482885485544, "Lung disorder": 2.136088260073278, "Lymphadenitis": 6.140920595934892, "Meningitis tuberculous": 94.97647903946046, "Metastases to liver": 2.8805693342087046, "Metastases to lung": 3.06413385708991, "Metastases to lymph nodes": 5.741533166035016, "Mouth ulceration": 4.5161053343012325, "Mucosal inflammation": 12.74216972681663, "Multiple organ dysfunction syndrome": 5.779657534825653, "Muscle twitching": 2.3890805251928344, "Myelodysplastic syndrome": 13.501437347217127, "Neoplasm progression": 4.055131988845357, "Nervous system disorder": 2.3308717899712668, "Neuropathy peripheral": 3.150177086443922, "Neurotoxicity": 4.538518941240761, "Neutropenia": 8.736550206618153, "Neutropenic sepsis": 19.917272888526316, "Neutrophil count decreased": 2.8221663869961584, "Neutrophil count increased": 13.52660983739053, "Neutrophilia": 17.766347641778545, "Off label use": 3.1286137132679395, "Pancytopenia": 3.626621420261626, "Pericardial effusion": 2.1902240367957204, "Plasma cell myeloma": 2.186982839596736, "Platelet count decreased": 3.1915693329160493, "Pleural effusion": 2.50345894286552, "Pneumonitis": 4.767284495053123, "Product use in unapproved indication": 2.903947403442673, "Productive cough": 2.0603241596788977, "Progressive multifocal leukoencephalopathy": 15.817642690554772, "Respiratory failure": 2.0478365526759195, "Sepsis": 4.1493828570764935, "Septic shock": 2.58453074251702, "Skin lesion": 2.3315305593421614, "Skin toxicity": 7.54373576629593, "Splenic rupture": 32.08687973890925, "Staphylococcal bacteraemia": 43.407933374971314, "Staphylococcal infection": 2.398277542913114, "Tachypnoea": 2.245387301961376, "Therapy non-responder": 7.106521740684257, "Therapy partial responder": 13.53813885111127, "Thrombocytopenia": 3.89356839420661, "Toxic epidermal necrolysis": 2.8568773211861616, "Treatment failure": 2.052303375484998, "Ureteric obstruction": 64.22892884661363, "Vasculitis": 2.6227559250273336, "Venoocclusive liver disease": 7.766363574614862, "Viral infection": 4.9977116655340055, "White blood cell count decreased": 3.775530833965232, "White blood cell count increased": 6.606922576013664}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/475.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/475.json
index 5a600cd9fe4..df777420af4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/475.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/475.json
@@ -1 +1 @@
-{"Erythema ": 2.777152689675432, "Feeling hot ": 2.115844783564018, "Guillain-Barre syndrome ": 9.293551023532748, "Lymphadenopathy ": 2.2752032308983794, "Mobility decreased ": 4.747096413492493, "Musculoskeletal stiffness ": 2.069948152290699, "Nasal congestion ": 3.3694067415776763, "Oropharyngeal pain ": 3.9931596685026944, "Pain in extremity ": 2.7038708746155344, "Paraesthesia ": 2.050604051519783, "Peripheral swelling ": 2.372252398173686, "Presyncope ": 2.7529746701902518, "Product administered at inappropriate site ": 27.68251193880776, "Pruritus ": 2.035750448817452, "Rhinorrhoea ": 5.86962851396378, "Syncope ": 2.014654238470554, "Urticaria ": 2.456011636788069, "Vaccination site erythema ": 6.60404947006523, "Vaccination site inflammation ": 9.927866538282045, "Vaccination site pain ": 3.617670764971858, "Vaccination site pruritus ": 3.257510176229579, "Vaccination site swelling ": 7.6327432351408895, "Vaccination site warmth ": 8.159192504145052}
\ No newline at end of file
+{"Electrocardiogram T wave inversion": 419.3855741897945, "Multiple sclerosis relapse": 43.94406459061196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/476.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/476.json
index 3f38a4e2788..284c2db5c0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/476.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/476.json
@@ -1 +1 @@
-{"Abdominal distension ": 15.486935086367971, "Adrenal insufficiency ": 4.052672897884921, "Adrenal suppression ": 283.42100845542467, "Appendicitis ": 33.41754705093679, "Appendicolith ": 111.87200361338776, "Arthritis ": 2.4227745147164628, "Ascites ": 10.217987173605913, "Asthma ": 19.73005994287271, "Asthmatic crisis ": 13.764111132203649, "Blood phosphorus increased ": 92.21780411189704, "Blood test abnormal ": 18.67924723638552, "Bronchiectasis ": 17.056452314801216, "Bronchitis ": 12.34759718772734, "Cardiac ventricular disorder ": 208.5790853082887, "Cardiogenic shock ": 21.148008884305774, "Cataract ": 4.093470979272404, "Chest discomfort ": 5.893763548734202, "Chronic obstructive pulmonary disease ": 17.08910215185045, "Chronic sinusitis ": 10.281796519533245, "Condition aggravated ": 4.573638202142165, "Constipation ": 2.62692446645283, "Cortisol decreased ": 44.476034969897945, "Cushing's syndrome ": 28.014714927562864, "Dermatitis allergic ": 5.730631207715992, "Dermatitis atopic ": 29.93921081434561, "Drug hypersensitivity ": 2.4333965565999502, "Dry mouth ": 4.871587674098312, "Dyspepsia ": 2.9989504174707724, "Dyspnoea ": 2.587226402157426, "Dyspnoea exertional ": 14.232755675170752, "Eczema ": 3.328455224832587, "Eosinophil count increased ": 9.27208295334308, "Eye pruritus ": 33.895582284287684, "Foetal malformation ": 111.650517533764, "Forced vital capacity decreased ": 277.4831182391939, "Full blood count abnormal ": 21.597496654113343, "Gastroenteritis ": 10.225340854419931, "General physical health deterioration ": 4.47672607666209, "Glaucoma ": 3.829593485783541, "Growth retardation ": 69.49114487978238, "Haemoptysis ": 16.221649773276933, "Hyponatraemia ": 4.003399027418299, "Incorrect route of product administration ": 10.593128999116129, "Lacrimation increased ": 23.424075558643075, "Lactose intolerance ": 216.58830413682105, "Loss of personal independence in daily activities ": 7.182622362253732, "Lower respiratory tract infection ": 3.513560235833496, "Middle insomnia ": 5.905972825192549, "Multiple organ dysfunction syndrome ": 9.016775606380053, "Nasal congestion ": 10.018999123764752, "Nasal oedema ": 33.36753249121173, "Nasal polyps ": 37.75355804313354, "Obstructive airways disorder ": 54.25864613570611, "Ocular hyperaemia ": 5.454881647425919, "Oedema ": 2.179725971660956, "Product dispensing error ": 30.41188208519931, "Productive cough ": 22.65635746529319, "Respiratory tract infection ": 11.9293819834894, "Rhinitis allergic ": 11.779245709294711, "Rhinorrhoea ": 4.650191328568088, "Rotator cuff syndrome ": 8.146768859504208, "Seasonal allergy ": 16.44867392666564, "Secretion discharge ": 12.738943698799538, "Sepsis ": 4.355590080763835, "Sleep disorder due to a general medical condition ": 26.75472397787636, "Sneezing ": 26.80200054473009, "Sputum discoloured ": 28.53213473183722, "Stress ": 11.498815424227177, "Swelling face ": 8.34543516679287, "Therapeutic product effect incomplete ": 19.11538597280329, "Therapeutic response decreased ": 6.34188033080476, "Trisomy 18 ": 348.6335225485826, "Ventricular fibrillation ": 62.3814075546732, "Weight increased ": 4.462946619308768, "Wheezing ": 23.597266514544344}
\ No newline at end of file
+{"Seizure": 20.684372935952613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/477.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/477.json
index 66bf71c565f..63ec018e450 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/477.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/477.json
@@ -1 +1 @@
-{"Abdominal distension ": 36.76873033829075, "Abdominal pain ": 6.44377869713319, "Abortion spontaneous ": 44.88515405519594, "Ascites ": 20.367545688404647, "Chest discomfort ": 6.415142431221763, "Ectopic pregnancy ": 682.5412023326703, "Off label use ": 3.5995989015777785, "Ovarian hyperstimulation syndrome ": 1027.3058360315404, "Tension ": 123.06189481328347}
\ No newline at end of file
+{"Drug ineffective": 3.5519917857728047, "Hereditary angioedema": 243.83730034031265}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/478.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/478.json
index ac450b5dacb..624ca8ba2bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/478.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/478.json
@@ -1 +1 @@
-{"Exposure during pregnancy ": 22.15336221890334, "Haemorrhage ": 13.988939581079691, "Hypersensitivity myocarditis ": 5041.417620442084, "Live birth ": 196.14851672721463}
\ No newline at end of file
+{"Abdominal pain upper": 2.1604485574137917, "Acute respiratory failure": 5.756416375761702, "Anosmia": 2.156678766324315, "Aphasia": 2.17303991250418, "Aspiration": 4.75929026938899, "Asthenia": 2.806804116652636, "Atelectasis": 3.7577919151614183, "Atrial fibrillation": 2.549526460230965, "Autoimmune disorder": 2.866852161161946, "Back disorder": 3.96975168885958, "Bacteraemia": 3.888690093487265, "Balance disorder": 3.278938069832794, "Blood magnesium decreased": 9.202451250214928, "Blood potassium decreased": 6.30595620601347, "Blood sodium decreased": 4.26185594098968, "COVID-19 pneumonia": 2.835437323855892, "Central venous catheterisation": 34.560489657803785, "Choking": 2.9498612247891223, "Concussion": 8.9172810656474, "Condition aggravated": 2.3767478608863386, "Dehydration": 2.940632680620053, "Diplopia": 6.9382630421549285, "Diverticulitis": 3.7990582536834814, "Dysphagia": 3.64168044297242, "Eye movement disorder": 5.286820300412947, "Failure to thrive": 11.745868033030764, "Fall": 5.475205637905272, "Fear": 2.305000881015459, "Feeding disorder": 3.548973781086381, "Feeling abnormal": 2.816261896413921, "Feeling cold": 2.938477271034456, "Foot fracture": 2.887743426747204, "Gait disturbance": 4.109704243129725, "Gait inability": 3.0748778697231858, "Gastric ulcer haemorrhage": 8.53966430168686, "Gastroenteritis": 4.008595158741052, "Haemorrhoids": 2.041104762101816, "Head injury": 3.303139302154598, "Hospice care": 31.54554206505523, "Hospitalisation": 2.305664361436756, "Hypersomnia": 5.087513095724264, "Hypervolaemia": 4.827315829800914, "Hypoaesthesia oral": 12.427589323305709, "Hypomagnesaemia": 6.584150088676262, "Hypophagia": 6.011332075825327, "Hypophosphataemia": 5.68891863279898, "Hypoxia": 2.549474865649298, "Inflammation": 2.059676701510875, "Intentional product use issue": 4.69041585991112, "Intestinal obstruction": 2.586779812852288, "Joint injury": 3.9161525349876736, "Leukocytosis": 3.2988755388621627, "Lung neoplasm malignant": 2.565299176101854, "Malnutrition": 11.32959981765502, "Mobility decreased": 2.464524274103693, "Motor dysfunction": 3.8288868154505455, "Muscle spasms": 2.497313669035319, "Muscular weakness": 5.637877128661003, "Musculoskeletal chest pain": 3.727798313730399, "Myasthenia gravis": 6.813466680856688, "Myasthenic syndrome": 594.6413670970958, "Nephrolithiasis": 3.364580774980174, "Nervousness": 2.1004215225844822, "Paraesthesia": 2.8597539324723216, "Paraesthesia oral": 15.399609317702334, "Performance status decreased": 7.632333974926924, "Peripheral coldness": 5.685801884561881, "Pneumonia": 2.3820300020231087, "Pneumonia aspiration": 2.8363868391695477, "Pneumothorax": 5.778507363024353, "Post procedural haemorrhage": 4.867379872549266, "Prescribed overdose": 5.580106995554496, "Product dose omission issue": 6.084423135177395, "Product substitution issue": 7.632033296057564, "Psychomotor hyperactivity": 2.2365288014895577, "Pulmonary fibrosis": 3.287769988996234, "Pulmonary mass": 7.148871893842365, "Respiratory failure": 2.0039097184111743, "Restless legs syndrome": 2.5400433727668816, "Rib fracture": 10.17001388322952, "Sinus tachycardia": 2.104927642603102, "Small cell lung cancer": 56.72582272075472, "Small cell lung cancer recurrent": 763.5603741761499, "Speech disorder": 3.0044186285394074, "Supraventricular tachycardia": 3.159163250369585, "Therapeutic product effect incomplete": 5.672589215228185, "Therapeutic response delayed": 85.94966454681091, "Therapeutic response shortened": 64.89857066725571, "Therapy interrupted": 7.525964569882879, "Torticollis": 12.4754585950007, "Ulcer haemorrhage": 5.150840792644057, "Unevaluable event": 16.06641990265106, "Urinary tract infection": 3.2972756571537345, "Ventricular extrasystoles": 3.630375204402277, "Viral infection": 4.3644019595714205, "Walking aid user": 10.844775682483965, "Weight decreased": 2.169741021286349, "Wheelchair user": 12.285128043700904, "Wound haemorrhage": 12.983648366956718, "Wound infection": 7.93707873892532, "Wrist fracture": 3.720009960551506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/479.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/479.json
index 7a10d4ddce7..10f5f875767 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/479.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/479.json
@@ -1 +1 @@
-{"Asthma ": 42.41947574465548, "Dyspnoea ": 8.057006880484847, "Therapeutic product effect incomplete ": 81.60966613860693}
\ No newline at end of file
+{"Anaphylactic reaction": 3.992144229332423, "Anaphylactoid reaction": 6.163378161538409, "Back pain": 9.682999541249233, "Blood pressure decreased": 3.4153555990514888, "Blood pressure increased": 4.1453542948639, "Blood pressure systolic increased": 4.886957626310301, "Body temperature increased": 6.951221013208412, "Bronchospasm": 6.6132311800444725, "Chest discomfort": 3.878330598836776, "Chest pain": 3.2907454108623195, "Chills": 7.450163964471832, "Cold sweat": 2.134677419133161, "Cyanosis": 11.465153343563037, "Dyspnoea": 3.295470083531685, "Erythema": 2.1901930157684064, "Feeling cold": 8.577465019364762, "Feeling hot": 2.224037535126375, "Flank pain": 6.981764310056512, "Flushing": 10.991342307963158, "Haemolysis": 5.9061059658649, "Heart rate increased": 3.4979186956850405, "Hyperhidrosis": 2.280769236112001, "Hypersensitivity": 3.344426321589622, "Hypertension": 7.321792831768243, "Hyperthermia": 18.2845897031136, "Hypotension": 5.378595335549892, "Hypothermia": 3.83884042865582, "Hypoxia": 7.254197857739967, "Infusion related reaction": 14.098299361186882, "Livedo reticularis": 24.941787286090964, "Meningitis aseptic": 110.00785822130943, "Oxygen saturation decreased": 17.461572368501066, "Pallor": 6.84359092637822, "Photophobia": 4.520342021563733, "Pyrexia": 2.1827605766833096, "Rash macular": 2.8194846157169127, "Rash papular": 2.0131844783679247, "Respiratory distress": 4.014462704988785, "Respiratory rate increased": 40.62222287428656, "Spinal pain": 5.6353014240831865, "Tachycardia": 7.838490486353848, "Tachypnoea": 20.039982720780134, "Throat tightness": 2.4527997892165545, "Transfusion-related acute lung injury": 132.70451860679563, "Tremor": 5.859612490221345, "Urticaria": 2.2322152343321764, "Vomiting": 2.259730106342267, "Wheezing": 3.5013917888017354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/48.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/48.json
index d486eb94bc5..773367a780b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/48.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/48.json
@@ -1 +1 @@
-{"Anxiety ": 5.083037549053048, "Aortic valve stenosis ": 884.2587082422037, "Asthma ": 9.637413100481346, "Atrial fibrillation ": 13.453299975763764, "Benign prostatic hyperplasia ": 254.50821919849128, "Bronchial secretion retention ": 874.8399510733706, "Bronchial wall thickening ": 1041.1970068847506, "Bronchiectasis ": 187.49994281058835, "Cardiac failure congestive ": 18.638656694126272, "Chest X-ray abnormal ": 271.4723925592004, "Cough ": 4.570850610605579, "Depression ": 7.249656867443968, "Diastolic dysfunction ": 427.6668497195958, "Full blood count abnormal ": 46.19825742893999, "Gastrooesophageal reflux disease ": 21.912182297773743, "Gout ": 93.34742101821249, "Hypertension ": 5.087445337647465, "Hypoacusis ": 41.49182391592704, "Intervertebral disc degeneration ": 184.7584371140261, "Loss of personal independence in daily activities ": 19.47849011603824, "Obstruction ": 652.4529975226078, "Obstructive airways disorder ": 78.8709776157945, "Osteoporosis ": 13.441191236542306, "Pain in extremity ": 2.606020428429274, "Productive cough ": 35.30089351652676, "Pulmonary function test abnormal ": 555.3912433028696, "Right atrial hypertrophy ": 12944.022537291452, "Right ventricular hypertrophy ": 1641.0702669251425, "Sleep apnoea syndrome ": 109.38417176708874, "Therapeutic product effect incomplete ": 18.54327645777149}
\ No newline at end of file
+{"Acquired haemophilia": 18.86042173698703, "Acute graft versus host disease": 61.84202687329019, "Acute graft versus host disease in intestine": 73.30958306565203, "Acute graft versus host disease in liver": 24.08664280295594, "Acute graft versus host disease in skin": 31.2462601006394, "Acute myeloid leukaemia recurrent": 8.45271162564363, "Acute respiratory distress syndrome": 3.1329514767719058, "Adenovirus infection": 178.70105505534744, "Anti-thyroid antibody positive": 24.21636794632178, "Aplasia pure red cell": 9.68095552912131, "Aplastic anaemia": 23.246263666370005, "Aspergillus infection": 14.969159915456345, "Autoimmune haemolytic anaemia": 53.86417069725539, "Autoimmune hypothyroidism": 49.79657281407666, "Autoimmune thyroiditis": 15.135092829012525, "BK virus infection": 71.37771578358002, "Bacteraemia": 11.649696858281512, "Bacterial infection": 2.2695764543994708, "Bacterial sepsis": 18.33734211287426, "Bacterial test": 93.83070218291016, "Bacterial test positive": 34.73286703398469, "Blood stem cell transplant failure": 183.5071366128074, "Blood thyroid stimulating hormone decreased": 15.07290508158228, "Blood thyroid stimulating hormone increased": 3.08905435011092, "Blood urine present": 10.38149405261197, "Bone marrow failure": 3.546789439691252, "Bone marrow transplant rejection": 58.26015247495518, "Bronchiolitis obliterans syndrome": 151.47421677442998, "Bronchopulmonary aspergillosis": 17.33685683456892, "Candida infection": 2.0819576448605708, "Central nervous system lesion": 8.664859486412732, "Central nervous system lymphoma": 23.96100733902436, "Cerebral aspergillosis": 85.21497400896588, "Chronic graft versus host disease": 23.536713361596025, "Chronic graft versus host disease in liver": 57.3642802435685, "Chronic graft versus host disease in skin": 83.58065674662686, "Chronic lymphocytic leukaemia": 7.294302226479661, "Clostridium difficile infection": 5.041782532279188, "Complications of bone marrow transplant": 83.89553257896878, "Coronavirus infection": 5.9961551031085545, "Crystal urine present": 146.825592127018, "Cutibacterium acnes infection": 163.0864917968889, "Cystitis haemorrhagic": 9.526304037272157, "Cystitis viral": 76.63998042800083, "Cytomegalovirus chorioretinitis": 16.070957347974588, "Cytomegalovirus infection": 49.0171216962021, "Cytomegalovirus infection reactivation": 121.3289253303567, "Cytomegalovirus viraemia": 69.65331113582533, "Cytopenia": 5.124383144539058, "Device related infection": 2.4154903287578917, "Diarrhoea haemorrhagic": 2.917869784957213, "Diarrhoea infectious": 32.44358979549113, "Diffuse large B-cell lymphoma": 14.821361568667095, "Diplopia": 2.3490437021388693, "Disability": 2.218022916328872, "Disseminated Bacillus Calmette-Guerin infection": 94.17811566088496, "Disseminated tuberculosis": 21.10524424180873, "Drug exposure before pregnancy": 16.5761617437518, "Drug ineffective for unapproved indication": 4.829766355376127, "Drug resistance": 4.333670594674488, "Dry throat": 4.097864232999535, "Encephalitis": 3.543579612068537, "Encephalitis viral": 47.95503344008096, "End stage renal disease": 17.765386501231763, "Endocrine ophthalmopathy": 33.568295375885285, "Enteritis": 9.734246503408553, "Enterobacter bacteraemia": 129.15432764238912, "Enterobacter infection": 17.04930928386789, "Enterococcal bacteraemia": 45.034012622649534, "Enterococcal infection": 13.305630869153516, "Eosinophil count increased": 5.0633914158842135, "Epstein-Barr viraemia": 133.55736150482883, "Epstein-Barr virus associated lymphoma": 58.524411615350914, "Epstein-Barr virus associated lymphoproliferative disorder": 28.893599278375344, "Epstein-Barr virus infection": 40.17073396879107, "Epstein-Barr virus infection reactivation": 46.18966625654815, "Escherichia bacteraemia": 23.26194720803139, "Escherichia infection": 7.166456510565337, "Escherichia urinary tract infection": 14.95646450630398, "Exophthalmos": 9.127196797719863, "Febrile neutropenia": 4.348995020437286, "Flushing": 2.7440354566123477, "Fungaemia": 13.854087202383887, "Fungal infection": 3.8640739939578608, "Gastroenteritis": 3.030407956677545, "Gastroenteritis adenovirus": 186.7711083357592, "Gastroenteritis norovirus": 36.10737791112788, "Goitre": 5.43219458563702, "Graft loss": 66.10240486558885, "Graft versus host disease": 39.745373946787936, "Graft versus host disease in gastrointestinal tract": 32.47365204494937, "Graft versus host disease in skin": 76.73224056918353, "Granuloma": 10.314099597676462, "Graves' disease": 47.36996760302877, "Grip strength decreased": 3.288554461047939, "Haematocrit decreased": 2.803929643877387, "Haemolytic anaemia": 2.241506975047836, "Haemophagocytic lymphohistiocytosis": 18.455838715641203, "Heart rate decreased": 2.553050430881372, "Hemiparesis": 2.201324466444449, "Hepatitis B": 14.500811536370795, "Hepatosplenomegaly": 8.570575819876012, "Herpes simplex": 49.48214126928027, "Herpes virus infection": 2.437823389196057, "Herpes zoster disseminated": 23.658932419314095, "Human herpesvirus 6 infection": 121.48065411422849, "Human herpesvirus 6 infection reactivation": 92.46221198142165, "Human polyomavirus infection": 92.8784264747334, "Hydrocephalus": 4.682436711751008, "Hyperthyroidism": 7.285169440682011, "Hypertransaminasaemia": 4.088262904753532, "Hypervolaemia": 3.168429663414219, "Hypogammaglobulinaemia": 13.583497524895552, "Immune reconstitution inflammatory syndrome": 4.145244336690006, "Immune system disorder": 3.176451434817756, "Immune thrombocytopenia": 11.6177984892787, "Immunosuppression": 8.32309731089317, "Increased appetite": 2.0517981229919884, "Increased tendency to bruise": 3.1736517117456544, "Infection": 3.14992721799683, "Infusion site erythema": 5.660486288631719, "Infusion site extravasation": 18.689215699090266, "Infusion site pain": 5.814330638778379, "Iron overload": 25.21342952758611, "JC virus infection": 85.77065040140113, "Kidney transplant rejection": 13.953842110620837, "Klebsiella bacteraemia": 46.69215331032196, "Klebsiella infection": 7.998029486975804, "Klebsiella sepsis": 17.30757656467466, "Leukaemia recurrent": 22.33921857858218, "Listeriosis": 44.42212890935629, "Lung infiltration": 3.723162305538428, "Lymphocyte count decreased": 26.75847960595123, "Lymphocyte percentage decreased": 48.00179187088992, "Lymphopenia": 22.882486309700685, "Lymphoproliferative disorder": 70.84075901806199, "Magnetic resonance imaging abnormal": 32.93880424044402, "Mean cell haemoglobin decreased": 43.40931262948704, "Meningitis tuberculous": 84.33319836427455, "Meningitis viral": 18.80294904643249, "Microsporidia infection": 261.446233281346, "Monocyte count decreased": 21.309170841325383, "Monocyte percentage increased": 85.04472138539107, "Mucormycosis": 10.528263091770622, "Mucosal inflammation": 21.679994003322246, "Multiple organ dysfunction syndrome": 9.257795103094058, "Multiple sclerosis": 2.964128517586913, "Multiple sclerosis relapse": 14.20534678057345, "Mycobacterium kansasii infection": 119.51710973591938, "Nephropathy toxic": 2.1588378328677718, "Neutropenia": 2.7291147392145367, "Neutrophil count increased": 4.187997844849394, "Neutrophil percentage increased": 27.36082287506253, "Nitrite urine present": 96.10601444904373, "Nocardiosis": 17.501022365313826, "Norovirus infection": 71.5477932790114, "Nystagmus": 2.563630173294541, "Odynophagia": 5.651073042950182, "Off label use": 4.4667212089138735, "Optic neuritis": 3.0634723740884326, "Oral herpes": 2.2170214169128597, "Organising pneumonia": 4.228648435678491, "Pancytopenia": 5.058853916693145, "Parainfluenzae virus infection": 15.929766477549755, "Paresis": 3.6346993772259433, "Paronychia": 8.22365875033466, "Pathogen resistance": 14.101036063994716, "Pericardial effusion": 2.932227881613545, "Pneumocystis jirovecii pneumonia": 10.567714786104702, "Pneumonia adenoviral": 328.10740233072767, "Pneumonia cytomegaloviral": 65.7852598678072, "Pneumonia respiratory syncytial viral": 28.06591156675037, "Pneumonitis": 5.187660126441732, "Polyomavirus viraemia": 136.39894313703408, "Post transplant lymphoproliferative disorder": 83.89915286852765, "Posterior reversible encephalopathy syndrome": 5.217693507018495, "Product use in unapproved indication": 4.3491461304417545, "Progressive multifocal leukoencephalopathy": 57.62342903644289, "Pseudomonal sepsis": 14.451518585882337, "Pseudomonas infection": 15.441605146230758, "Pulmonary alveolar haemorrhage": 6.161411891175391, "Pulmonary haemorrhage": 9.09943350663765, "Red blood cells urine positive": 46.00479487808789, "Red cell distribution width increased": 8.266113922647603, "Respiratory disorder": 3.0986990965992365, "Respiratory failure": 3.9103554922225823, "Respiratory syncytial virus infection": 4.161180326374071, "Rhinovirus infection": 7.192764305775098, "Richter's syndrome": 33.71190430521264, "Sarcoidosis": 3.669329837836999, "Sepsis": 5.037602647017315, "Septic shock": 3.5752921034614227, "Serum ferritin increased": 2.98048107312372, "Sinus bradycardia": 2.2245398698973062, "Skin mass": 3.69273722596366, "Staphylococcal bacteraemia": 24.851566003065315, "Staphylococcal infection": 4.887658416117423, "Stem cell transplant": 24.30221743950744, "Systemic candida": 10.944273074655358, "Therapeutic response decreased": 2.0785364773907613, "Therapy partial responder": 4.95754913166955, "Thrombotic microangiopathy": 15.464088598319258, "Transplant dysfunction": 23.621535539723585, "Transplant failure": 109.40141026983612, "Transplant rejection": 50.77694595102959, "Urinary sediment present": 185.234680641476, "Urinary tract infection bacterial": 15.61293214656312, "Urine abnormality": 25.36874430316404, "Urine analysis abnormal": 10.103762871270929, "Urine ketone body present": 19.361307958764133, "Varicella": 2.5629311145017697, "Varicella zoster virus infection": 32.05755841070756, "Vascular device infection": 8.008228457635743, "Venoocclusive disease": 63.0841236046378, "Venoocclusive liver disease": 27.01128834419746, "Viraemia": 100.56153201173872, "Viral haemorrhagic cystitis": 25.51175571293593, "Viral infection": 2.594396593850773, "White blood cells urine positive": 36.658149077224735}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/480.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/480.json
index bbe53bf9554..06dd4ecb9d9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/480.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/480.json
@@ -1 +1 @@
-{"Abdominal distension ": 3.0141542916084347, "Abdominal hernia ": 4.254243176166805, "Abdominal rigidity ": 3.7720066505416714, "Abnormal weight gain ": 3.4480330966570056, "Accident ": 2.157436460917814, "Accidental overdose ": 2.263475022174904, "Accidental underdose ": 6.462448160298963, "Administration site bruise ": 39.98048944320949, "Age-related macular degeneration ": 6.422883223678346, "Ankle fracture ": 2.988355680426995, "Aortic aneurysm ": 3.8968635724481535, "Aortic valve stenosis ": 3.88821789437354, "Application site bruise ": 16.79240931345673, "Arrhythmia ": 2.429975022402502, "Back pain ": 5.205701949766551, "Biliary colic ": 2.9879697977471733, "Bladder pain ": 2.032389211148656, "Blood alkaline phosphatase increased ": 5.74986346288816, "Blood calcium abnormal ": 11.403199381818732, "Blood calcium decreased ": 2.4195198182046336, "Blood calcium increased ": 45.7803592108281, "Blood cholesterol increased ": 2.6659602824308366, "Blood parathyroid hormone decreased ": 11.281123712948332, "Blood parathyroid hormone increased ": 24.425864054447946, "Blood pressure increased ": 2.1899074140895967, "Blood test abnormal ": 2.070895571845993, "Blood uric acid increased ": 7.3133874597412465, "Bone disorder ": 3.1646359767512524, "Bone fissure ": 34.85181838608185, "Bone pain ": 9.08629431651199, "Breast disorder ": 4.144944076315723, "Breast neoplasm ": 6.69696218509038, "Bronchial carcinoma ": 9.34636783690194, "Bronchitis ": 2.3143560612293226, "C-telopeptide increased ": 194.19005441068973, "Calcinosis ": 11.234325312645652, "Calciphylaxis ": 3.964565335270956, "Calculus urinary ": 4.602650583245115, "Cardiac pacemaker insertion ": 2.582728309175193, "Cardiac valve disease ": 3.0276647605849765, "Carotid artery stenosis ": 2.284131476835194, "Cataract ": 2.2514456164716066, "Cervical vertebral fracture ": 4.110897482964797, "Choking sensation ": 2.808218466459006, "Cholelithiasis ": 3.3551089132951804, "Clavicle fracture ": 4.862508655464087, "Coccydynia ": 10.42685379391597, "Colon cancer ": 2.532868328252632, "Comminuted fracture ": 36.5878024675228, "Complication associated with device ": 2.4956854580937464, "Craniofacial fracture ": 2.0073446116279654, "Cystocele ": 9.60153123624882, "Dental caries ": 2.320237037927315, "Dental restoration failure ": 11.498646097245176, "Depression ": 2.347216914815383, "Device dislocation ": 12.878530470532452, "Device failure ": 2.7651860017942638, "Device loosening ": 44.55729213838868, "Device use error ": 3.779206077775167, "Diplegia ": 2.16844663818829, "Drop attacks ": 12.753593277078698, "Dysentery ": 4.168522765881235, "Dyspepsia ": 2.6183927994982232, "Dysstasia ": 3.092741874930284, "Emphysema ": 2.021449684948051, "Fall ": 6.879441677356433, "Feeding disorder ": 2.338893675408068, "Femoral neck fracture ": 32.40047420047031, "Femur fracture ": 19.008392016031515, "Fibula fracture ": 8.959882516500628, "Fluid intake reduced ": 2.2533251950915405, "Foot fracture ": 2.3599087106467174, "Fracture ": 3.5924614077263577, "Fracture nonunion ": 35.04906616736135, "Fracture pain ": 29.293571628827525, "Fractured sacrum ": 19.424240771987712, "Gait disturbance ": 2.968184617740329, "Gallbladder operation ": 3.3746376991599685, "Gastritis ": 2.2396138309663254, "Gastroenteritis ": 3.731922840555556, "Gastrointestinal inflammation ": 2.985178015294516, "Gingival disorder ": 2.81331691899648, "Groin pain ": 3.8070888145895, "Growing pains ": 28.14653158629961, "Haemorrhoids ": 4.518052595958407, "Hair growth abnormal ": 2.7084564208969177, "Hand fracture ": 3.89901127226738, "Head injury ": 2.017524715744212, "Heart rate irregular ": 2.703183201535672, "Hernial eventration ": 75.74112674475187, "Hiatus hernia ": 3.7366287009973895, "Hip arthroplasty ": 3.598758391775771, "Hip fracture ": 5.908190019578335, "Hip surgery ": 4.1271030528084, "Hot flush ": 2.079970881909908, "Humerus fracture ": 14.91403053005988, "Hypercalcaemia ": 28.35482959898496, "Hypercalciuria ": 39.98048944320949, "Hyperparathyroidism ": 5.065236133670494, "Hyperuricaemia ": 2.276734074500842, "Incontinence ": 2.057538055118504, "Incorrect product administration duration ": 15.616738779076888, "Infarction ": 2.76975931127729, "Inguinal hernia ": 8.07887824496958, "Injection site bruising ": 17.679281144932983, "Injection site discolouration ": 4.862508655464087, "Injection site discomfort ": 2.190581797628984, "Injection site erythema ": 4.886822139028914, "Injection site haematoma ": 7.84501235718108, "Injection site haemorrhage ": 15.54348744820253, "Injection site hypersensitivity ": 2.041207973284883, "Injection site mass ": 2.266437151881663, "Injection site nodule ": 2.0263454077594787, "Injection site paraesthesia ": 3.4597242153714096, "Injection site rash ": 2.101336374302681, "Injection site urticaria ": 2.5996134981906494, "Injury associated with device ": 6.15273551830467, "Intervertebral disc protrusion ": 2.876095986875926, "Intestinal obstruction ": 2.6225883692580148, "Intestinal polyp ": 5.780735429657907, "Investigation ": 62.73565020039175, "Jaw fracture ": 3.038616370650522, "Joint arthroplasty ": 6.511616270248247, "Joint dislocation ": 4.720388649758985, "Joint injury ": 2.053027434450842, "Leukaemia ": 2.091603351736853, "Ligament sprain ": 3.0017927295228373, "Lividity ": 14.421763753569222, "Loose tooth ": 5.481972941660784, "Lower limb fracture ": 2.7359903862311987, "Lumbar spinal stenosis ": 4.577759645746135, "Lumbar vertebral fracture ": 20.522031982771782, "Lung adenocarcinoma ": 2.414260537036764, "Lung neoplasm malignant ": 2.439717162561026, "Mass ": 2.3331873544068142, "Medical device removal ": 27.189727481559476, "Micturition urgency ": 9.363612741052922, "Mixed anxiety and depressive disorder ": 5.085042893945065, "Mobility decreased ": 2.8227922562309216, "Muscle spasms ": 4.99039528807127, "Musculoskeletal chest pain ": 2.6651434596131174, "Musculoskeletal discomfort ": 2.404211225708773, "Nail discolouration ": 2.4712843628663403, "Neoplasm ": 2.8417359295310503, "Nephrolithiasis ": 4.077386729404583, "Nerve compression ": 2.4100372250050723, "Neuralgia ": 2.414078231833297, "Nocturia ": 2.6123865708179914, "Onychoclasis ": 2.9684354636912853, "Osteitis ": 5.9543516813421, "Osteitis deformans ": 28.586770555592462, "Osteoarthritis ": 3.5436182546070243, "Osteonecrosis of jaw ": 2.78173828062088, "Osteoporotic fracture ": 5.802024149413668, "Ovarian cancer ": 2.204324663928343, "Pain in extremity ": 2.96589565331395, "Pain in jaw ": 2.558108499960419, "Parkinson's disease ": 2.9627899025069766, "Patella fracture ": 13.04652586452305, "Pathological fracture ": 11.0471333534074, "Pelvic fracture ": 25.022099327775365, "Pelvic pain ": 2.919926359122316, "Periodontitis ": 4.84510271618761, "Phlebitis ": 4.457912071928293, "Plasma cell myeloma ": 2.533891197232653, "Plasmacytoma ": 4.2327796081995, "Pollakiuria ": 5.715341974846749, "Polyuria ": 2.596850090387034, "Post procedural complication ": 2.792260712174081, "Post procedural infection ": 2.870297609602072, "Product administered at inappropriate site ": 5.143637701479135, "Product storage error ": 10.576015123161758, "Prosthesis implantation ": 59.85738486807363, "Radius fracture ": 5.2058989634648105, "Reflux gastritis ": 5.97991362414407, "Renal colic ": 5.665711244064321, "Renal pain ": 3.127244615048202, "Rheumatic disorder ": 5.344742168332026, "Rib fracture ": 5.246461201054666, "Sacral pain ": 4.455969636610332, "Sciatica ": 5.432031300962419, "Shoulder fracture ": 9.222699851601687, "Skin odour abnormal ": 2.112505025176776, "Sleep disorder due to general medical condition, insomnia type ": 7.760791120764014, "Spinal column injury ": 6.148992879148731, "Spinal compression fracture ": 5.697580988489302, "Spinal disorder ": 7.635313217323497, "Spinal fracture ": 26.165878585346945, "Spinal pain ": 9.959901018564103, "Sternal fracture ": 6.404162111241828, "Thoracic vertebral fracture ": 16.522823903008476, "Throat cancer ": 3.730448881944247, "Thrombophlebitis ": 4.319420273354766, "Thyroid mass ": 2.67737949605418, "Tibia fracture ": 10.303883257081171, "Tongue coated ": 2.8366328577809226, "Tongue erythema ": 2.8831152868919405, "Tooth abscess ": 2.900563769782061, "Tooth discolouration ": 2.492577333048867, "Tooth disorder ": 2.924460618253312, "Tooth infection ": 2.0423670135112846, "Toothache ": 2.873034675402179, "Upper limb fracture ": 8.501288982942949, "Urinary bladder polyp ": 38.47208248559957, "Urinary incontinence ": 5.962328050010876, "Urine abnormality ": 4.530873981586754, "Urine calcium increased ": 157.2870200041915, "Urine odour abnormal ": 2.8350637743882787, "Urine output increased ": 4.081167707268572, "Uterine prolapse ": 14.07737883444102, "Varicose vein ": 2.6850119467338605, "Vein disorder ": 2.094989132521753, "Vertebroplasty ": 190.75191381203325, "Vertigo ": 4.170485478139744, "Vitamin D decreased ": 9.45027254818665, "Vitamin D increased ": 20.14436392433228, "Weight decreased ": 2.253131953826845, "Weight increased ": 2.7357320590447864, "Wrist fracture ": 11.449877682352518}
\ No newline at end of file
+{"Adverse event": 164.5255632399122, "Keratopathy": 8587.701475032678, "Off label use": 13.844541038139392, "Platelet count decreased": 52.41792579823187, "Thrombocytopenia": 33.06527751327042, "Visual acuity reduced": 336.0945697421141}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/481.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/481.json
index 9e35b77a992..b8b197125a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/481.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/481.json
@@ -1 +1 @@
-{"Blister ": 70.05679981979254, "Erythema ": 20.47093656268918, "Lip erosion ": 4132.516782492467, "Mucosal erosion ": 3630.7298320394366, "Pyrexia ": 3.4385160850659418, "Stevens-Johnson syndrome ": 147.1076537627112, "Thermal burn ": 1213.750854150354}
\ No newline at end of file
+{"Erythema": 2.77522476625964, "Feeling hot": 2.1143979841978284, "Guillain-Barre syndrome": 9.287196737883969, "Lymphadenopathy": 2.2736461717243497, "Mobility decreased": 4.743849852869837, "Musculoskeletal stiffness": 2.068532799264035, "Nasal congestion": 3.367103316474033, "Oropharyngeal pain": 3.990427955643188, "Pain in extremity": 2.702004711865583, "Paraesthesia": 2.049181602097058, "Peripheral swelling": 2.370629652202456, "Presyncope": 2.751092465083319, "Product administered at inappropriate site": 27.66358741540768, "Pruritus": 2.034332228047195, "Rhinorrhoea": 5.865614095846057, "Syncope": 2.013248398348335, "Urticaria": 2.454305781818164, "Vaccination site erythema": 6.599531224063584, "Vaccination site inflammation": 9.92107956309956, "Vaccination site pain": 3.615193606358792, "Vaccination site pruritus": 3.2552832468659143, "Vaccination site swelling": 7.627520568986903, "Vaccination site warmth": 8.153613813418167}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/482.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/482.json
index b1f5ca706a1..1d16a2ec64f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/482.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/482.json
@@ -1 +1 @@
-{"Anaemia ": 2.5792267260461395, "Diabetes mellitus ": 8.072037215031001, "Diarrhoea ": 3.1447333866357035, "Hypertriglyceridaemia ": 80.38347635221086, "Lipodystrophy acquired ": 94.48533793058571, "Myocardial infarction ": 3.742796175861603, "Neutropenia ": 3.0090889166084143, "Pancreatitis ": 7.360631430953967, "Premature baby ": 15.677764662153026, "Seizure ": 2.604130789549862}
\ No newline at end of file
+{"Abdominal distension": 15.475725009923003, "Adrenal insufficiency": 4.049743445521332, "Adrenal suppression": 283.2160330588304, "Appendicitis": 33.39337789154102, "Appendicolith": 111.79109350009143, "Arthritis": 2.421022889394436, "Ascites": 10.210597010696176, "Asthma": 19.71576562189286, "Asthmatic crisis": 13.754159925507574, "Blood phosphorus increased": 92.15110845501242, "Blood test abnormal": 18.66574066722333, "Bronchiectasis": 17.044121340034994, "Bronchitis": 12.337923061915731, "Cardiac ventricular disorder": 208.4283184430703, "Cardiogenic shock": 21.132713607207823, "Cataract": 4.090511290356331, "Chest discomfort": 5.889291507833833, "Chronic obstructive pulmonary disease": 17.07673704005015, "Chronic sinusitis": 10.274363621390227, "Condition aggravated": 4.570328156045422, "Constipation": 2.6250244869509607, "Cortisol decreased": 44.44388182022068, "Cushing's syndrome": 27.994461255010663, "Dermatitis allergic": 5.726488059295906, "Dermatitis atopic": 29.91756489879539, "Drug hypersensitivity": 2.431636894202695, "Dry mouth": 4.868064146819111, "Dyspepsia": 2.9967818223841345, "Dyspnoea": 2.585314399833528, "Dyspnoea exertional": 14.222459100758416, "Eczema": 3.3260488589173933, "Eosinophil count increased": 9.265379838599872, "Eye pruritus": 33.871060887724845, "Foetal malformation": 111.56980245669033, "Forced vital capacity decreased": 277.28250946491227, "Full blood count abnormal": 21.581871607110187, "Gastroenteritis": 10.217947959514346, "General physical health deterioration": 4.473488057828438, "Glaucoma": 3.826825285078561, "Growth retardation": 69.44089591960237, "Haemoptysis": 16.209915613016683, "Hyponatraemia": 4.000503564609007, "Incorrect route of product administration": 10.585468672126982, "Lacrimation increased": 23.407131235001675, "Lactose intolerance": 216.4316374980787, "Loss of personal independence in daily activities": 7.177426701916373, "Lower respiratory tract infection": 3.511019991099193, "Middle insomnia": 5.901703726046209, "Multiple organ dysfunction syndrome": 9.010254218856833, "Nasal congestion": 10.01175277717234, "Nasal oedema": 33.34341303341489, "Nasal polyps": 37.72626133614623, "Obstructive airways disorder": 54.21938165648433, "Ocular hyperaemia": 5.450937861083248, "Oedema": 2.178150033761519, "Product dispensing error": 30.38988706625284, "Productive cough": 22.63996277750792, "Respiratory tract infection": 11.920756091004456, "Rhinitis allergic": 11.770730484843506, "Rhinorrhoea": 4.646828692250423, "Rotator cuff syndrome": 8.140880015081061, "Seasonal allergy": 16.436782612582842, "Secretion discharge": 12.729734709100953, "Sepsis": 4.35243985136492, "Sleep disorder due to a general medical condition": 26.73537109073033, "Sneezing": 26.78261297547725, "Sputum discoloured": 28.51150452412092, "Stress": 11.490498786996463, "Swelling face": 8.339397720824868, "Therapeutic product effect incomplete": 19.101548018336004, "Therapeutic response decreased": 6.337294482959495, "Trisomy 18": 348.3814931288393, "Ventricular fibrillation": 62.33626339741704, "Weight increased": 4.459717892756594, "Wheezing": 23.579238763612658}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/483.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/483.json
index 4b7ed27af9d..463e8683b7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/483.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/483.json
@@ -1 +1 @@
-{"Abnormal loss of weight ": 2.518791676737123, "Acidosis ": 5.369864855215974, "Acquired phimosis ": 381.0232514944572, "Acute kidney injury ": 4.002862802738257, "Anal abscess ": 7.40268720806141, "Aneurysm ruptured ": 12.850542403650108, "Arterial occlusive disease ": 4.753662482475782, "Balanitis candida ": 74.76539324589217, "Balanoposthitis ": 187.3669685846062, "Benign prostatic hyperplasia ": 3.797803918459095, "Bladder cancer ": 2.7807098160331005, "Blood creatine increased ": 12.144871828577896, "Blood creatinine abnormal ": 4.117532216656451, "Blood creatinine increased ": 3.71974371891938, "Blood glucose abnormal ": 4.774778028303274, "Blood glucose decreased ": 2.314089912872085, "Blood glucose fluctuation ": 6.830270971858616, "Blood glucose increased ": 3.9498058250295713, "Blood ketone body increased ": 63.91517442758578, "Blood ketone body present ": 12.92633837426362, "Blood triglycerides increased ": 3.4707863201197453, "Blood urea increased ": 3.329751403912263, "Body mass index abnormal ": 40.55775519864466, "Brain stem infarction ": 15.07737908596566, "Breast cancer female ": 2.6563092224026814, "Calculus urinary ": 5.930497112910753, "Candida infection ": 13.982095517778374, "Cardiac failure ": 2.883318147945532, "Cardiac failure acute ": 2.3230811399883606, "Cardiac failure chronic ": 8.036677488926395, "Cerebral infarction ": 5.8897648948622265, "Coronary artery occlusion ": 4.484737493990828, "Coronary artery stenosis ": 4.468416731824837, "Creatinine renal clearance decreased ": 2.1802354118979985, "Cystitis ": 9.618313294933923, "Cystitis haemorrhagic ": 6.090763236179657, "Dehydration ": 8.24253988309443, "Diabetes mellitus inadequate control ": 5.2130056582385285, "Diabetic coma ": 6.733549963189873, "Diabetic foot ": 7.420458825835947, "Diabetic ketoacidosis ": 54.43984167908836, "Diabetic ketosis ": 103.26586684387912, "Diabetic metabolic decompensation ": 7.778886649909975, "Diabetic neuropathy ": 3.35204112246369, "Dry mouth ": 4.296742544268177, "Dyslipidaemia ": 3.6318232571104634, "Dysuria ": 11.393662912467086, "Emphysematous cystitis ": 77.30325469241441, "Endocarditis ": 3.2046747205024726, "Epididymitis ": 13.382194469434127, "Epigastric discomfort ": 3.3412907780508707, "Erectile dysfunction ": 2.222560341064772, "Escherichia urinary tract infection ": 20.797468515968166, "Euglycaemic diabetic ketoacidosis ": 90.34910364123796, "Extremity necrosis ": 8.039995467351243, "Flank pain ": 4.178131263543519, "Flatulence ": 2.0038485941245545, "Fluid intake reduced ": 8.884714581426127, "Fournier's gangrene ": 83.95445172046969, "Fungal infection ": 21.74862464924447, "Furuncle ": 3.018185129630537, "Gangrene ": 6.784016523611853, "Gastroenteritis ": 2.783675872716062, "Genital burning sensation ": 27.206930303027928, "Genital candidiasis ": 78.82024705584077, "Genital discomfort ": 33.901066116527474, "Genital erythema ": 42.676746027912806, "Genital infection ": 145.0537804183924, "Genital infection female ": 309.191941329436, "Genital infection fungal ": 81.01304316088434, "Genital infection male ": 254.8328181873844, "Genital pain ": 9.760304600112203, "Genital rash ": 27.029737906590864, "Genital swelling ": 45.59450032021551, "Genital tract inflammation ": 67.08217086896731, "Genitourinary tract infection ": 82.0181039857135, "Glomerular filtration rate abnormal ": 6.56700836661905, "Glomerular filtration rate decreased ": 40.43731938826015, "Glucose urine present ": 51.36101939593361, "Glycosuria ": 49.744970889524495, "Glycosylated haemoglobin abnormal ": 16.319198488376887, "Glycosylated haemoglobin decreased ": 19.655874266202463, "Glycosylated haemoglobin increased ": 13.664059049579135, "Haematocrit increased ": 15.745149589955863, "Haematuria ": 3.8979238657451742, "Haemoglobin increased ": 6.959852139368632, "Heat illness ": 24.154608449695, "Hunger ": 5.251004652904629, "Hydronephrosis ": 4.744957034518556, "Hyperglycaemia ": 6.583103900314509, "Hyperglycaemic hyperosmolar nonketotic syndrome ": 37.898165800217264, "Hyperkalaemia ": 2.480542075197812, "Hyperlipasaemia ": 15.1116064716842, "Hypernatraemia ": 11.670001466419324, "Hyperphosphataemia ": 4.91337582311263, "Hypoglycaemia ": 4.319723087341925, "Hypoglycaemic coma ": 2.455203147437629, "Hypoglycaemic encephalopathy ": 12.465053757170208, "Hypophagia ": 2.833560573740726, "Hypovolaemia ": 5.053126299056451, "Incontinence ": 3.490767767671846, "Infarction ": 2.330326848833378, "Intentional dose omission ": 3.593928862141766, "Intentional product misuse ": 5.097934772386181, "Ischaemic stroke ": 3.390414864013496, "Ketoacidosis ": 104.63732628172863, "Ketonuria ": 97.40088812751004, "Ketosis ": 70.77371146235515, "Lactic acidosis ": 3.777293977954274, "Lacunar infarction ": 6.77736895532869, "Leg amputation ": 6.286919909786217, "Limb injury ": 2.185039692439216, "Lipase increased ": 2.7326896554857965, "Localised infection ": 2.008748838720217, "Marasmus ": 16.753327165652003, "Metabolic acidosis ": 9.14700474709596, "Metabolic alkalosis ": 6.216469818177934, "Microalbuminuria ": 31.561539761373663, "Micturition disorder ": 3.838346858488418, "Micturition urgency ": 9.496834676371662, "Muscle atrophy ": 2.9616085589871965, "Necrosis ": 4.569749567753556, "Necrotising fasciitis ": 13.160895997716914, "Nocturia ": 13.655739215533105, "Orchitis ": 25.09707029000772, "Pancreatitis ": 2.0965333584408072, "Pancreatitis necrotising ": 6.584749238463214, "Pemphigoid ": 3.2174127437509936, "Penile erythema ": 47.41690754376895, "Penile pain ": 9.46494293104424, "Penis disorder ": 15.460999022848425, "Perineal abscess ": 59.45241731900098, "Peripheral arterial occlusive disease ": 3.6371742611429374, "Phimosis ": 81.24626573227967, "Physical deconditioning ": 2.2544684170706257, "Pollakiuria ": 19.0907632991636, "Polycythaemia ": 19.174419530142018, "Polydipsia ": 10.307484050938182, "Polyuria ": 34.11144886349959, "Prerenal failure ": 11.208260245431289, "Prostatitis ": 38.072872679888285, "Pruritus genital ": 85.30780393204091, "Pyelonephritis ": 36.509121217540105, "Pyelonephritis acute ": 59.45778427360257, "Pyelonephritis chronic ": 49.51964846722398, "Pyuria ": 11.562380839500122, "Renal abscess ": 17.583193771631024, "Renal colic ": 4.7761402664022725, "Renal cyst ": 2.1802354118979985, "Renal disorder ": 2.231413556772083, "Renal function test abnormal ": 3.1404216714216275, "Renal impairment ": 3.477573718945655, "Renal pain ": 2.497374721450217, "Retinopathy ": 3.371922198659732, "Sepsis ": 2.1369484547088144, "Skin fissures ": 2.224156203732873, "Systemic candida ": 6.997512362771251, "Therapy cessation ": 5.789759683461301, "Thirst ": 11.70840791392076, "Thrombotic cerebral infarction ": 43.483268509844834, "Toe amputation ": 25.99462519736602, "Type 2 diabetes mellitus ": 3.123563045580182, "Underdose ": 2.51625728458078, "Urethritis ": 42.50346171480211, "Urinary incontinence ": 4.582217489823612, "Urinary retention ": 2.137579875037405, "Urinary tract disorder ": 4.379137090374609, "Urinary tract infection ": 24.06163086509158, "Urinary tract infection bacterial ": 13.725104036814848, "Urinary tract infection fungal ": 86.12694751725085, "Urine abnormality ": 7.188746573197485, "Urine analysis abnormal ": 13.100425612770389, "Urine ketone body present ": 60.20756411542976, "Urine odour abnormal ": 10.759014790669577, "Urine output decreased ": 2.70738106831247, "Urine output increased ": 13.545877315322372, "Urosepsis ": 34.39395866274349, "Vaginal infection ": 41.36237883510333, "Vulvitis ": 65.95026107523228, "Vulvovaginal burning sensation ": 11.274349233144648, "Vulvovaginal candidiasis ": 41.21270498778955, "Vulvovaginal discomfort ": 9.72382697305281, "Vulvovaginal dryness ": 6.768052558502779, "Vulvovaginal inflammation ": 19.13337162544912, "Vulvovaginal mycotic infection ": 50.62573441711976, "Vulvovaginal pain ": 4.541726296017542, "Vulvovaginal pruritus ": 47.7090247619072, "Vulvovaginitis ": 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\ No newline at end of file
+{"Abdominal distension": 36.76873033829075, "Abdominal pain": 6.44377869713319, "Abortion spontaneous": 44.88515405519594, "Ascites": 20.367545688404647, "Chest discomfort": 6.414917289968495, "Ectopic pregnancy": 682.5412023326703, "Off label use": 3.599457129817321, "Ovarian hyperstimulation syndrome": 1027.3058360315404, "Tension": 123.06189481328347}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/484.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/484.json
index be59a4caba7..5e0a16acebb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/484.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/484.json
@@ -1 +1 @@
-{"Drug interaction ": 5.094191919462285}
\ No newline at end of file
+{"Exposure during pregnancy": 22.15336221890334, "Haemorrhage": 13.988939581079691, "Hypersensitivity myocarditis": 5041.417620442084, "Live birth": 196.14851672721463}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/485.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/485.json
index ea040a0f6d9..d5280b93d0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/485.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/485.json
@@ -1 +1 @@
-{"Osteonecrosis of jaw ": 240.23676751424856}
\ No newline at end of file
+{"Asthma": 42.41947574465548, "Dyspnoea": 8.056887189675694, "Therapeutic product effect incomplete": 81.60966613860693}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/486.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/486.json
index 6f0a2600d10..6a15267fb51 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/486.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/486.json
@@ -1 +1 @@
-{"Asthenia ": 2.8253715454656567, "Blood pressure increased ": 5.482675094782659, "Decreased appetite ": 4.7920367431162, "Dehydration ": 5.536733083882675, "Diarrhoea ": 3.849154145997309, "Disease progression ": 14.195170977663262, "Dysphonia ": 16.328775921289758, "Haemoglobin decreased ": 3.209095355534594, "Hospitalisation ": 4.123921254698673, "Hypertension ": 5.738788442464368, "Hypertensive crisis ": 15.13123134719624, "Hypothyroidism ": 9.370291237474746, "Intestinal perforation ": 25.87302839628541, "Lethargy ": 2.8195867854336782, "Malignant neoplasm progression ": 4.415054407236185, "Mucosal inflammation ": 15.17872435955698, "Palmar-plantar erythrodysaesthesia syndrome ": 21.99549428320448, "Pleural effusion ": 4.489202604559692, "Posterior reversible encephalopathy syndrome ": 27.495954427717464, "Product dose omission issue ": 2.777737073257769, "Stomatitis ": 5.376051162405831, "Urinary tract infection ": 3.483635647762165}
\ No newline at end of file
+{"Abdominal distension": 3.0141542916084347, "Abdominal hernia": 4.254243176166805, "Abdominal rigidity": 3.7720066505416714, "Abnormal weight gain": 3.4480330966570056, "Accident": 2.157436460917814, "Accidental overdose": 2.263475022174904, "Accidental underdose": 6.462448160298963, "Administration site bruise": 39.98048944320949, "Age-related macular degeneration": 6.422883223678346, "Ankle fracture": 2.988355680426995, "Aortic aneurysm": 3.8968635724481535, "Aortic valve stenosis": 3.88821789437354, "Application site bruise": 16.79240931345673, "Arrhythmia": 2.429975022402502, "Back pain": 5.205701949766551, "Biliary colic": 2.9879697977471733, "Bladder pain": 2.032389211148656, "Blood alkaline phosphatase increased": 5.74986346288816, "Blood calcium abnormal": 11.403199381818732, "Blood calcium decreased": 2.4195198182046336, "Blood calcium increased": 45.7803592108281, "Blood cholesterol increased": 2.6659602824308366, "Blood parathyroid hormone decreased": 11.281123712948332, "Blood parathyroid hormone increased": 24.425864054447946, "Blood pressure increased": 2.18986877095032, "Blood test abnormal": 2.070895571845993, "Blood uric acid increased": 7.3133874597412465, "Bone disorder": 3.1646359767512524, "Bone fissure": 34.85181838608185, "Bone pain": 9.08629431651199, "Breast disorder": 4.144944076315723, "Breast neoplasm": 6.69696218509038, "Bronchial carcinoma": 9.34636783690194, "Bronchitis": 2.3142165110306574, "C-telopeptide increased": 194.19005441068973, "Calcinosis": 11.234325312645652, "Calciphylaxis": 3.964565335270956, "Calculus urinary": 4.602650583245115, "Cardiac pacemaker insertion": 2.582728309175193, "Cardiac valve disease": 3.0276647605849765, "Carotid artery stenosis": 2.284131476835194, "Cataract": 2.2514456164716066, "Cervical vertebral fracture": 4.110897482964797, "Choking sensation": 2.808218466459006, "Cholelithiasis": 3.3551089132951804, "Clavicle fracture": 4.862508655464087, "Coccydynia": 10.42685379391597, "Colon cancer": 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35.04906616736135, "Fracture pain": 29.293571628827525, "Fractured sacrum": 19.424240771987712, "Gait disturbance": 2.9681304127230788, "Gallbladder operation": 3.3746376991599685, "Gastritis": 2.2396138309663254, "Gastroenteritis": 3.731922840555556, "Gastrointestinal inflammation": 2.985178015294516, "Gingival disorder": 2.81331691899648, "Groin pain": 3.8070888145895, "Growing pains": 28.14653158629961, "Haemorrhoids": 4.518052595958407, "Hair growth abnormal": 2.7084564208969177, "Hand fracture": 3.896146306799657, "Head injury": 2.017524715744212, "Heart rate irregular": 2.703183201535672, "Hernial eventration": 75.74112674475187, "Hiatus hernia": 3.7366287009973895, "Hip arthroplasty": 3.598758391775771, "Hip fracture": 5.908190019578335, "Hip surgery": 4.1271030528084, "Hot flush": 2.079970881909908, "Humerus fracture": 14.91403053005988, "Hypercalcaemia": 28.35482959898496, "Hypercalciuria": 39.98048944320949, "Hyperparathyroidism": 5.065236133670494, "Hyperuricaemia": 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3.038616370650522, "Joint arthroplasty": 6.511616270248247, "Joint dislocation": 4.720388649758985, "Joint injury": 2.053027434450842, "Leukaemia": 2.091603351736853, "Ligament sprain": 3.0017927295228373, "Lividity": 14.421763753569222, "Loose tooth": 5.481972941660784, "Lower limb fracture": 2.7359903862311987, "Lumbar spinal stenosis": 4.577759645746135, "Lumbar vertebral fracture": 20.522031982771782, "Lung adenocarcinoma": 2.414260537036764, "Lung neoplasm malignant": 2.439717162561026, "Mass": 2.3331873544068142, "Medical device removal": 27.189727481559476, "Micturition urgency": 9.363612741052922, "Mixed anxiety and depressive disorder": 5.085042893945065, "Mobility decreased": 2.8227922562309216, "Muscle spasms": 4.99039528807127, "Musculoskeletal chest pain": 2.6651434596131174, "Musculoskeletal discomfort": 2.404211225708773, "Nail discolouration": 2.4712843628663403, "Neoplasm": 2.8417359295310503, "Nephrolithiasis": 4.076705836822811, "Nerve compression": 2.4100372250050723, "Neuralgia": 2.414078231833297, "Nocturia": 2.6123865708179914, "Onychoclasis": 2.9684354636912853, "Osteitis": 5.9543516813421, "Osteitis deformans": 28.586770555592462, "Osteoarthritis": 3.5436182546070243, "Osteonecrosis of jaw": 2.78173828062088, "Osteoporotic fracture": 5.802024149413668, "Ovarian cancer": 2.204324663928343, "Pain in extremity": 2.965879854030173, "Pain in jaw": 2.558108499960419, "Parkinson's disease": 2.9627899025069766, "Patella fracture": 13.04652586452305, "Pathological fracture": 11.0471333534074, "Pelvic fracture": 25.022099327775365, "Pelvic pain": 2.919926359122316, "Periodontitis": 4.84510271618761, "Phlebitis": 4.457912071928293, "Plasma cell myeloma": 2.533891197232653, "Plasmacytoma": 4.2327796081995, "Pollakiuria": 5.715341974846749, "Polyuria": 2.596850090387034, "Post procedural complication": 2.792260712174081, "Post procedural infection": 2.870297609602072, "Product administered at inappropriate site": 5.143637701479135, "Product storage error": 10.576015123161758, "Prosthesis implantation": 59.85738486807363, "Radius fracture": 5.2058989634648105, "Reflux gastritis": 5.97991362414407, "Renal colic": 5.665711244064321, "Renal pain": 3.127244615048202, "Rheumatic disorder": 5.344742168332026, "Rib fracture": 5.246461201054666, "Sacral pain": 4.455969636610332, "Sciatica": 5.432031300962419, "Shoulder fracture": 9.222699851601687, "Skin odour abnormal": 2.112505025176776, "Sleep disorder due to general medical condition, insomnia type": 7.760791120764014, "Spinal column injury": 6.148992879148731, "Spinal compression fracture": 5.697580988489302, "Spinal disorder": 7.635313217323497, "Spinal fracture": 26.165878585346945, "Spinal pain": 9.959901018564103, "Sternal fracture": 6.404162111241828, "Thoracic vertebral fracture": 16.522823903008476, "Throat cancer": 3.730448881944247, "Thrombophlebitis": 4.319420273354766, "Thyroid mass": 2.67737949605418, "Tibia fracture": 10.303883257081171, "Tongue coated": 2.8366328577809226, "Tongue erythema": 2.8831152868919405, "Tooth abscess": 2.900563769782061, "Tooth discolouration": 2.492577333048867, "Tooth disorder": 2.924460618253312, "Tooth infection": 2.0423670135112846, "Toothache": 2.873034675402179, "Upper limb fracture": 8.501288982942949, "Urinary bladder polyp": 38.47208248559957, "Urinary incontinence": 5.962328050010876, "Urine abnormality": 4.530873981586754, "Urine calcium increased": 157.2870200041915, "Urine odour abnormal": 2.8350637743882787, "Urine output increased": 4.081167707268572, "Uterine prolapse": 14.07737883444102, "Varicose vein": 2.6850119467338605, "Vein disorder": 2.094989132521753, "Vertebroplasty": 190.75191381203325, "Vertigo": 4.170485478139744, "Vitamin D decreased": 9.45027254818665, "Vitamin D increased": 20.14436392433228, "Weight decreased": 2.253131953826845, "Weight increased": 2.7357320590447864, "Wrist fracture": 11.449877682352518}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/487.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/487.json
index ec3f1db1859..b95c0e6faaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/487.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/487.json
@@ -1 +1 @@
-{"Drug ineffective ": 4.000329467768764}
\ No newline at end of file
+{"Blister": 70.05679981979254, "Erythema": 20.470736356972413, "Lip erosion": 4132.516782492467, "Mucosal erosion": 3630.7298320394366, "Pyrexia": 3.438442653718942, "Stevens-Johnson syndrome": 147.1076537627112, "Thermal burn": 1213.750854150354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/488.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/488.json
index abcc4f8564a..d41a2b761e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/488.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/488.json
@@ -1 +1 @@
-{"Acquired gene mutation ": 15.66309242300454, "Alopecia ": 2.609580771734368, "Anaemia ": 2.423286621719629, "Ascites ": 2.5619762736121907, "Aspartate aminotransferase increased ": 2.349733571990744, "Blood alkaline phosphatase increased ": 2.154862427453137, "Body height decreased ": 4.470140625322871, "Bone cancer ": 13.85700191686983, "Bone disorder ": 4.578510109014138, "Bone lesion ": 33.43844664110897, "Bone pain ": 3.261699810429383, "Breast cancer ": 12.554780723963908, "Breast cancer metastatic ": 111.6333709849885, "Breast cancer recurrent ": 53.30427663977488, "Breast discharge ": 21.601470772894395, "Carbohydrate antigen 15-3 increased ": 167.92569400882076, "Carcinoembryonic antigen increased ": 45.54556704109553, "Cardiomegaly ": 2.881611804439055, "Cytopenia ": 4.135166399868111, "Decreased immune responsiveness ": 20.96056018690132, "Disease progression ": 4.453659987427071, "Dry skin ": 3.1249402598627363, "Eructation ": 3.427008741726635, "Feeding disorder ": 2.369856892883748, "Full blood count abnormal ": 2.3037884716534367, "Full blood count decreased ": 3.764609736582575, "Glomerular filtration rate decreased ": 2.3858953826322846, "Granulocytopenia ": 5.26642854822267, "Haematocrit decreased ": 4.667494169906409, "Haematotoxicity ": 9.399724061338697, "Haemoglobin decreased ": 2.3343048956768078, "Hepatic failure ": 2.0136392652279995, "Hepatic lesion ": 9.348119059420426, "Hepatotoxicity ": 10.44203837597922, "Hormone receptor positive HER2 negative breast cancer ": 267.2708878944481, "Hot flush ": 2.466065006994868, "Hydronephrosis ": 3.888096545962058, "Hyperglycaemia ": 2.7489752485532386, "Injection site necrosis ": 8.739781669322744, "Invasive ductal breast carcinoma ": 14.67636563893952, "Laboratory test abnormal ": 3.21337529523442, "Leukopenia ": 6.363089801299656, "Lymphoedema ": 7.559811564097917, "Malignant neoplasm progression ": 24.749582372148613, "Malignant pleural effusion ": 14.244076771502511, "Metastases to bone ": 78.41901248631949, "Metastases to breast ": 129.858097469737, "Metastases to central nervous system ": 10.43434985679579, "Metastases to chest wall ": 65.47261589686659, "Metastases to liver ": 52.18814367212594, "Metastases to lung ": 30.172297113663348, "Metastases to lymph nodes ": 35.74068675046074, "Metastases to pelvis ": 33.37662939641732, "Metastases to peritoneum ": 18.90708836760346, "Metastases to pleura ": 58.41925527347942, "Metastases to skin ": 22.289994602626408, "Metastases to spine ": 45.354334178589305, "Metastases to the mediastinum ": 49.8933315420318, "Metastases to thorax ": 182.33121832079317, "Metastasis ": 23.47502587778088, "Metastatic neoplasm ": 12.260579057756733, "Mucosal inflammation ": 4.880115684873705, "Musculoskeletal discomfort ": 3.443028425450144, "Myelosuppression ": 2.101981274351814, "Neoplasm progression ": 27.262878949959, "Neutropenia ": 21.21152773278048, "Neutrophil count decreased ": 7.108391500316962, "Nodule ": 2.2788997650081018, "Osteolysis ": 16.755677717001202, "Osteonecrosis of jaw ": 10.949193842622188, "Osteosclerosis ": 28.43729889478194, "PIK3CA-activated mutation ": 127.98164662635736, "Platelet count decreased ": 2.758389019864369, "Platelet count increased ": 2.1715958955811145, "Pleural effusion ": 4.109089641700626, "Pneumonitis ": 2.8620424005194227, "Product dose omission in error ": 6.374283779589493, "Pulmonary mass ": 5.03761006940257, "Red blood cell count decreased ": 4.046474150677802, "Second primary malignancy ": 2.633145386339633, "Spinal pain ": 5.987144827668145, "Staphylococcal infection ": 2.4473078309516287, "Therapy partial responder ": 9.39073316115756, "Thrombocytopenia ": 3.1474728457384846, "Thrombophlebitis ": 5.551954059874265, "Tooth fracture ": 3.3563262451346207, "Transaminases increased ": 2.5598138979098537, "Tumour marker increased ": 54.70990257553316, "White blood cell count decreased ": 4.07136591133085}
\ No newline at end of file
+{"Anaemia": 2.5792267260461395, "Diabetes mellitus": 8.072037215031001, "Diarrhoea": 3.1447071425330213, "Hypertriglyceridaemia": 80.38347635221086, "Lipodystrophy acquired": 94.48533793058571, "Myocardial infarction": 3.742796175861603, "Neutropenia": 3.0089595347473383, "Pancreatitis": 7.360631430953967, "Premature baby": 15.677764662153026, "Seizure": 2.6038421358089177}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/489.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/489.json
index 38ca64d5f89..0c6f4e1e930 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/489.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/489.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 11.460503571753144, "Aspartate aminotransferase increased ": 10.08115173824039, "Cholestasis ": 30.52912981358692, "Granulomatous liver disease ": 906.3244014727634, "Hepatic encephalopathy ": 61.340033465269, "Hepatitis fulminant ": 196.6941678065769, "Immune reconstitution inflammatory syndrome ": 122.55659360463837, "Insomnia ": 4.998444574232191, "Jaundice ": 13.111238054977, "Leukopenia ": 6.816101975563304, "Lymphopenia ": 42.21135955493028, "Neutropenia ": 3.100126465937859, "Pneumonia ": 2.4793974479225422, "Renal failure ": 4.777526412678703, "Tachypnoea ": 34.84183565777153, "Tuberculosis liver ": 7613.25089238314}
\ No newline at end of file
+{"Abnormal loss of weight": 2.318804580895704, "Abscess limb": 3.7135787763418793, "Acidosis": 4.94348161498165, "Acquired phimosis": 350.7704538900232, "Acute kidney injury": 3.693755177697476, "Anal abscess": 6.814915019608272, "Aneurysm ruptured": 11.830240313058722, "Arterial occlusive disease": 4.376216116312304, "Balanitis candida": 68.82891461212704, "Balanoposthitis": 172.48346928606423, "Benign prostatic hyperplasia": 3.496260949525925, "Bladder cancer": 2.559911394640309, "Blood creatine increased": 11.180521567494935, "Blood creatinine abnormal": 3.790608327679292, "Blood creatinine increased": 3.4243101837432905, "Blood glucose abnormal": 4.3956258523771385, "Blood glucose decreased": 2.130332108857288, "Blood glucose fluctuation": 6.28788861034112, "Blood glucose increased": 3.6595598994552736, "Blood ketone body increased": 58.83999369638104, "Blood ketone body present": 11.90001827425242, "Blood triglycerides increased": 3.195194767612203, "Blood urea increased": 3.065349153823127, "Body mass index abnormal": 37.33757606767102, "Brain stem infarction": 13.88023864336072, "Breast cancer female": 2.4454035074935554, "Calculus urinary": 5.459629602704652, "Candida infection": 12.871699827951344, "Cardiac failure": 2.654089451596198, "Cardiac failure acute": 2.1386307975277274, "Cardiac failure chronic": 7.398541628674737, "Cerebral infarction": 5.475349693460229, "Coronary artery occlusion": 4.128635020652854, "Coronary artery stenosis": 4.113628952555229, "Creatinine renal clearance decreased": 2.0071275594470874, "Cystitis": 8.854479253093299, "Cystitis haemorrhagic": 5.607149586070795, "Dehydration": 7.626294969588381, "Diabetes mellitus inadequate control": 4.799021988636817, "Diabetic coma": 6.198909028747671, "Diabetic foot": 6.831279838303735, "Diabetic ketoacidosis": 50.11387989588625, "Diabetic ketosis": 95.06597602674458, "Diabetic metabolic decompensation": 7.161253558941774, "Diabetic neuropathy": 3.08589345691975, "Dry mouth": 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74.57950754489234, "Genital infection male": 234.59845650896727, "Genital pain": 8.985343778539445, "Genital rash": 24.883544478523486, "Genital swelling": 41.974229710828745, "Genital tract inflammation": 61.75579153760319, "Genitourinary tract infection": 75.5057731662356, "Glomerular filtration rate abnormal": 6.045588894643836, "Glomerular filtration rate decreased": 37.225351671922496, "Glucose urine present": 47.28269332852632, "Glycosuria": 45.79477279449783, "Glycosylated haemoglobin abnormal": 15.02345359389014, "Glycosylated haemoglobin decreased": 18.0952202899212, "Glycosylated haemoglobin increased": 12.578866016411542, "Haematocrit increased": 14.494949779411778, "Haematuria": 3.626787131937715, "Haemoglobin increased": 6.8805500546271885, "Heat illness": 22.23676104522316, "Hunger": 5.067605644335838, "Hydronephrosis": 4.36820427325827, "Hyperglycaemia": 6.060227982865659, "Hyperglycaemic hyperosmolar nonketotic syndrome": 34.88895970917199, "Hyperkalaemia": 2.28324334746878, "Hyperlipasaemia": 13.9117711774439, "Hypernatraemia": 10.743340543396483, "Hyperphosphataemia": 4.523265307877876, "Hypoglycaemia": 3.988589617827455, "Hypoglycaemic coma": 2.2602542265372394, "Hypoglycaemic encephalopathy": 11.4753498725451, "Hypophagia": 2.60856795859727, "Hypovolaemia": 4.651903423733287, "Incontinence": 3.2135975427940684, "Infarction": 2.1453026938640214, "Intentional dose omission": 3.3085723725597003, "Intentional product misuse": 4.693045002269752, "Ischaemic stroke": 3.2030736999487424, "Ketoacidosis": 96.32441320468398, "Ketonuria": 89.66649393402682, "Ketosis": 65.15371973409829, "Lactic acidosis": 3.477332015647255, "Lacunar infarction": 6.239252837874376, "Leg amputation": 6.278320630749732, "Limb injury": 2.3164298695629157, "Lipase increased": 2.5157095298606813, "Marasmus": 15.423142331090466, "Metabolic acidosis": 8.420570279138053, "Metabolic alkalosis": 5.722896762965076, "Microalbuminuria": 29.055495541353828, "Micturition disorder": 3.533588421433233, "Micturition urgency": 8.928704682433906, "Muscle atrophy": 2.7264548077039303, "Necrosis": 4.206912057893623, "Necrotising fasciitis": 12.1159002581085, "Nocturia": 12.571355222653995, "Orchitis": 23.10434468443439, "Pancreatitis necrotising": 6.061924929812348, "Pemphigoid": 2.961940526699547, "Penile erythema": 43.652004320617706, "Penile pain": 9.51480003623119, "Penis disorder": 15.07728781427142, "Perineal abscess": 54.73198283284652, "Peripheral arterial occlusive disease": 3.3483885916745493, "Phimosis": 74.79459415392452, "Physical deconditioning": 2.0754680621713124, "Pollakiuria": 17.70527095782819, "Polycythaemia": 17.651908595360727, "Polydipsia": 9.489025398317878, "Polyuria": 31.40220305198992, "Prerenal failure": 10.31833635734904, "Prostatitis": 35.04961403803839, "Pruritus genital": 78.53272962310454, "Pyelonephritis": 33.60963417318678, "Pyelonephritis acute": 54.7364002623841, "Pyelonephritis chronic": 45.58790470114312, "Pyuria": 10.644355551112712, "Renal abscess": 16.18712503379913, "Renal colic": 4.396921057243385, "Renal cyst": 2.0071275594470874, "Renal disorder": 2.053920980992109, "Renal function test abnormal": 2.89107839537477, "Renal impairment": 3.217724028905978, "Renal pain": 2.677960035299016, "Retinopathy": 3.1041939267824974, "Skin fissures": 2.0475625783410822, "Systemic candida": 6.441921561523345, "Therapy cessation": 5.330040607055018, "Thirst": 11.010254166091208, "Thrombotic cerebral infarction": 40.03071790110597, "Toe amputation": 23.930535023438445, "Type 2 diabetes mellitus": 2.875536110256487, "Underdose": 2.316455382475221, "Urethritis": 39.12866287542441, "Urinary incontinence": 4.290453227357603, "Urinary retention": 2.004273730320844, "Urinary tract disorder": 4.031442303062748, "Urinary tract infection": 22.19494365474461, "Urinary tract infection bacterial": 12.635329997490274, "Urinary tract infection fungal": 79.28837300154973, "Urine abnormality": 6.617965353631789, "Urine analysis abnormal": 12.060240800981637, "Urine ketone body present": 55.4267246337684, "Urine odour abnormal": 9.904724585235602, "Urine output decreased": 2.492415323430719, "Urine output increased": 12.470323322151131, "Urosepsis": 31.662570643640848, "Vaginal infection": 38.07786338606903, "Vulvitis": 60.71383697154238, "Vulvovaginal burning sensation": 10.379159076147577, "Vulvovaginal candidiasis": 37.94008651385791, "Vulvovaginal discomfort": 8.951765374410034, "Vulvovaginal dryness": 6.230682763262948, "Vulvovaginal inflammation": 17.614229007768127, "Vulvovaginal mycotic infection": 46.60536060093054, "Vulvovaginal pain": 4.738020579030365, "Vulvovaginal pruritus": 43.92037757777416, "Vulvovaginitis": 186.9292182340031, "Weight decreased": 6.610054768009659}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/49.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/49.json
index 42b49e3c010..7c4bee63b0a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/49.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/49.json
@@ -1 +1 @@
-{"Respiratory failure ": 27.31797610905545}
\ No newline at end of file
+{"Anxiety": 5.083037549053048, "Aortic valve stenosis": 884.2587082422037, "Asthma": 9.637413100481346, "Atrial fibrillation": 13.452932723740984, "Benign prostatic hyperplasia": 254.50821919849128, "Bronchial secretion retention": 874.8399510733706, "Bronchial wall thickening": 1041.1970068847506, "Bronchiectasis": 187.49994281058835, "Cardiac failure congestive": 18.63724693547656, "Chest X-ray abnormal": 271.4723925592004, "Cough": 4.57080821621237, "Depression": 7.249656867443968, "Diastolic dysfunction": 427.6668497195958, "Full blood count abnormal": 46.19825742893999, "Gastrooesophageal reflux disease": 21.912182297773743, "Gout": 93.34742101821249, "Hypertension": 5.087392819013005, "Hypoacusis": 41.48833084888079, "Intervertebral disc degeneration": 184.7584371140261, "Loss of personal independence in daily activities": 19.47849011603824, "Obstruction": 652.4529975226078, "Obstructive airways disorder": 78.8709776157945, "Osteoporosis": 13.441191236542306, "Pain in extremity": 2.606006647714897, "Productive cough": 35.30089351652676, "Pulmonary function test abnormal": 555.3912433028696, "Right atrial hypertrophy": 12944.022537291452, "Right ventricular hypertrophy": 1641.0702669251425, "Sleep apnoea syndrome": 109.33563566879263, "Therapeutic product effect incomplete": 18.54327645777149}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/490.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/490.json
index aa6f860f511..2408713aae4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/490.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/490.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 6.167782667245704, "Accidental overdose ": 3.253932905014447, "Acute pulmonary oedema ": 7.313833577725554, "Aggression ": 54.633926663663935, "Agitation ": 6.742071344111657, "Altered state of consciousness ": 5.8775045454376045, "Amnesia ": 2.469953105065148, "Anger ": 25.77277814290632, "Anticonvulsant drug level increased ": 37.00809436042189, "Apathy ": 4.520259805327356, "Ataxia ": 14.899451907782906, "Aura ": 22.55356930889413, "Balance disorder ": 6.42614955601004, "Behaviour disorder ": 12.374557642448412, "Cognitive disorder ": 5.50257768510383, "Confusional state ": 2.0225248441151784, "Crying ": 3.5104329365665867, "Delirium ": 2.337125726675548, "Delusion ": 10.619229147939722, "Depressed mood ": 3.606328785464148, "Depression ": 2.5250618784263463, "Diplopia ": 5.439592715976101, "Disturbance in attention ": 2.109607166475475, "Drug eruption ": 4.319073140031302, "Drug interaction ": 3.9101719069636114, "Drug level decreased ": 11.044919091057174, "Drug withdrawal convulsions ": 30.46257916292862, "Drug-induced liver injury ": 4.540196246850226, "Dysarthria ": 7.500747393907536, "Dyskinesia ": 3.749273033091782, "Emotional disorder ": 3.707431638699628, "Encephalopathy ": 2.860885076501177, "Epilepsy ": 9.16621615839612, "Erectile dysfunction ": 4.650333661325357, "Euphoric mood ": 12.61722814648986, "Exfoliative rash ": 17.966812824868196, "Exposure during pregnancy ": 2.960218242025225, "Fall ": 3.088240962111503, "Focal dyscognitive seizures ": 64.32892925188159, "Gait disturbance ": 5.531031494229634, "Gaze palsy ": 27.749640592152737, "General physical health deterioration ": 3.4681400779768103, "Generalised tonic-clonic seizure ": 5.354562078945678, "Hallucination ": 3.0691786676542123, "Hallucination, auditory ": 5.23944941306573, "Hallucination, visual ": 6.176800216476574, "Head injury ": 6.676504151030104, "Heart rate irregular ": 3.795845124338, "Hepatic cytolysis ": 2.4883904648832336, "Homicidal ideation ": 58.91360866932415, "Hostility ": 23.94001159076202, "Hyperammonaemia ": 8.345077691863196, "Hypersomnia ": 2.383497799806398, "Hypothermia ": 11.451326894691636, "Hypotonia ": 2.877735763930547, "Increased appetite ": 4.068681134055331, "Intentional overdose ": 6.698387422911089, "Irritability ": 23.393412907221617, "Liver injury ": 3.229319690224901, "Mental status changes ": 2.8803371331903262, "Mitral valve disease ": 34.563785348141884, "Mood altered ": 12.627323155305202, "Multiple-drug resistance ": 81.50660345662867, "Nervousness ": 2.674890638713748, "Paranoia ": 5.685450323534483, "Partial seizures ": 23.135567874753814, "Persecutory delusion ": 17.46253025377572, "Personality change ": 13.786134240113562, "Petit mal epilepsy ": 9.475416310747857, "Physical assault ": 70.48429610073784, "Pneumonia aspiration ": 5.604614723136496, "Product administered to patient of inappropriate age ": 6.763873098312874, "Psychiatric symptom ": 8.522408418008784, "Psychomotor hyperactivity ": 4.176428754160562, "Psychotic disorder ": 16.435413817933814, "Restlessness ": 5.022740264063131, "Salivary hypersecretion ": 4.646227622764214, "Sedation ": 2.2902415693451306, "Seizure ": 9.315850743240084, "Self-destructive behaviour ": 9.94347716623241, "Skin lesion ": 2.007819986359565, "Slow speech ": 33.280715340706934, "Somnolence ": 6.647284504299689, "Staphylococcus test positive ": 30.773475985095885, "Status epilepticus ": 26.01142895891065, "Sudden unexplained death in epilepsy ": 107.67430235135168, "Suicidal ideation ": 8.418510214846759, "Suicide attempt ": 12.30075627524149, "Toxic epidermal necrolysis ": 5.53517838660358, "Urinary retention ": 2.9912568767672965, "Vertigo ": 4.485276549107328, "Weight increased ": 3.709066018644176, "Wrong patient received product ": 17.40906569057788}
\ No newline at end of file
+{"Drug interaction": 5.094191919462285}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/491.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/491.json
index 8305d1693ff..d9fd5fc556c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/491.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/491.json
@@ -1 +1 @@
-{"Adverse event ": 4.02219839339429, "Atrial fibrillation ": 2.555762416166219, "Cardiac disorder ": 4.501018091845299, "Cerebrovascular accident ": 4.285712575350503, "Depressed mood ": 2.050213171226122, "Depression ": 2.416578072400478, "Dyspepsia ": 2.408050438087031, "Flatulence ": 3.172138014361128, "Gastrointestinal disorder ": 2.9483016541245406, "Glomerular filtration rate decreased ": 21.12201785750508, "Hospitalisation ": 3.4804074557423306, "Impaired work ability ": 5.213511559014525, "Implantable defibrillator insertion ": 95.1580602402994, "Inappropriate schedule of product administration ": 4.172117018832758, "Nasal congestion ": 2.8220767946630883, "Nephrolithiasis ": 4.086792359180077, "Neuropathy peripheral ": 4.080738861899907, "Poor quality sleep ": 11.020034157197278, "Pre-existing condition improved ": 171.6906000939662, "Product dose omission in error ": 44.89261774555358, "Product dose omission issue ": 13.547254056044514, "Product physical issue ": 22.632470588815448, "Proteinuria ": 10.428904441011738, "Renal disorder ": 2.878488758846533, "Renal impairment ": 3.52735308160889, "Rhinorrhoea ": 5.519666429598175, "Sinusitis ": 2.801534104790178, "Surgery ": 4.916651430912984, "Temperature intolerance ": 21.084889731617096, "Transient ischaemic attack ": 5.38140934991934, "Weight increased ": 2.4688031127314165, "Wrong technique in product usage process ": 2.434036577458104}
\ No newline at end of file
+{"Osteonecrosis of jaw": 240.23676751424856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/492.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/492.json
index fb931a2f7c6..acd029f7f11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/492.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/492.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.431940454828467, "Abdominal pain upper ": 2.3898946325210093, "Alanine aminotransferase increased ": 4.270871736889416, "Amylase increased ": 22.13792651303727, "Angioedema ": 3.2202998347327254, "Anuria ": 3.4153728605027305, "Aspartate aminotransferase increased ": 4.082101635048918, "Blister ": 3.795626199092832, "Blood alkaline phosphatase increased ": 2.6738826119177266, "Blood bilirubin increased ": 2.4439085118506894, "Blood cholesterol increased ": 2.0093432894038763, "Blood glucose abnormal ": 4.378626138673745, "Blood glucose decreased ": 2.4125704585516154, "Blood glucose fluctuation ": 7.83069628745645, "Blood glucose increased ": 12.042865731722754, "Blood triglycerides increased ": 5.639325784012208, "Blood urea increased ": 3.420815113803165, "Cardiac failure ": 3.016822651236728, "Cataract ": 2.306374864559677, "Cholelithiasis ": 7.085289593069954, "Cholestasis ": 5.328536015386185, "Chromaturia ": 2.939282431119877, "Dermatitis bullous ": 23.051075740275486, "Diabetes mellitus ": 5.565848531106048, "Diabetes mellitus inadequate control ": 9.686584580573502, "Dry throat ": 5.06631974949236, "Dysphagia ": 2.18326425019801, "Eczema ": 4.109838102645774, "Encephalopathy ": 2.8150101306743283, "Face oedema ": 2.042691965661161, "Fall ": 2.666869653173653, "Fear ": 2.968450015096424, "Femur fracture ": 4.537199751920985, "Gait inability ": 2.101608930772624, "Gamma-glutamyltransferase increased ": 8.293864592374037, "Gastritis ": 2.2698036122980376, "Generalised oedema ": 3.4019329067955275, "Glycosylated haemoglobin increased ": 13.7917851740662, "Hepatic cytolysis ": 5.882952060704632, "Hepatic steatosis ": 9.965332850329574, "Hepatitis ": 3.419609152059509, "Hyperglycaemia ": 3.7372087191152663, "Hypertension ": 2.0966598540794985, "Hypoglycaemia ": 6.824173978957802, "Hypoglycaemic coma ": 2.7076728133784727, "Incorrect dose administered ": 2.523397623914536, "Jaundice ": 5.058606614424945, "Lactic acidosis ": 2.8842817085669443, "Limb injury ": 2.77480984054728, "Lipase increased ": 26.78752759263563, "Liver function test abnormal ": 2.3870294615828054, "Lower limb fracture ": 3.3910265893179345, "Oedema peripheral ": 2.801378047410939, "Osteoarthritis ": 2.8716166591156584, "Pancreatic carcinoma ": 4.494502709009152, "Pancreatitis ": 9.407410761028077, "Pancreatitis acute ": 13.386847840851493, "Pemphigoid ": 91.6266499843558, "Pruritus ": 2.091835421999153, "Pulmonary oedema ": 2.320313057417405, "Renal disorder ": 3.578620797460533, "Skin exfoliation ": 3.789127149376613, "Transaminases increased ": 4.6432241461890085}
\ No newline at end of file
+{"Asthenia": 2.825259149440704, "Blood pressure increased": 5.482578847563192, "Decreased appetite": 4.791990251317845, "Dehydration": 5.536437504736545, "Diarrhoea": 3.8491220170975184, "Disease progression": 14.195170977663262, "Dysphonia": 16.328775921289758, "Haemoglobin decreased": 3.209095355534594, "Hospitalisation": 4.123921254698673, "Hypertension": 5.73872918200886, "Hypertensive crisis": 15.13123134719624, "Hypothyroidism": 9.370291237474746, "Intestinal perforation": 25.87302839628541, "Lethargy": 2.8195867854336782, "Malignant neoplasm progression": 4.415054407236185, "Mucosal inflammation": 15.17872435955698, "Palmar-plantar erythrodysaesthesia syndrome": 21.99549428320448, "Pleural effusion": 4.48878929896535, "Posterior reversible encephalopathy syndrome": 27.495954427717464, "Product dose omission issue": 2.777737073257769, "Stomatitis": 5.376051162405831, "Urinary tract infection": 3.483635647762165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/493.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/493.json
index 7cc7aaa21f3..aca42f62f39 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/493.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/493.json
@@ -1 +1 @@
-{"Acute graft versus host disease ": 8.473399684785521, "Acute kidney injury ": 2.913212315839871, "Acute respiratory distress syndrome ": 6.5106134136318365, "Agranulocytosis ": 4.13365249352052, "Aspergillus infection ": 6.04004687555517, "Bone marrow failure ": 13.67011843057223, "Bronchiectasis ": 6.120267609181379, "Bronchopulmonary aspergillosis ": 18.756910583858662, "Cardiogenic shock ": 3.7547533692140367, "Cholestasis ": 2.407620749303092, "Clostridium difficile colitis ": 4.737792072897808, "Coagulopathy ": 2.730106209427165, "Colitis ": 2.268487688612998, "Condition aggravated ": 2.089118306521664, "Cytomegalovirus chorioretinitis ": 149.11839336348416, "Cytomegalovirus colitis ": 163.57203200345444, "Cytomegalovirus enteritis ": 140.93962494464978, "Cytomegalovirus enterocolitis ": 49.528379822420405, "Cytomegalovirus gastritis ": 168.0671433188008, "Cytomegalovirus hepatitis ": 132.7945815142211, "Cytomegalovirus infection ": 60.69375850001629, "Cytomegalovirus infection reactivation ": 86.31765211281565, "Cytomegalovirus syndrome ": 473.6931449373272, "Cytomegalovirus test positive ": 14.490029374334371, "Cytomegalovirus viraemia ": 174.12577136506067, "Cytopenia ": 15.098563552720655, "Depressed level of consciousness ": 3.6070946670252138, "Disseminated cytomegaloviral infection ": 406.71840639623866, "Drug ineffective ": 3.0927815298781858, "Drug ineffective for unapproved indication ": 8.909125511865607, "Drug reaction with eosinophilia and systemic symptoms ": 4.233421784225564, "Drug resistance ": 64.03121628065877, "Encephalitis cytomegalovirus ": 342.37811265980645, "Encephalopathy ": 3.9401389606454673, "Enterococcal infection ": 15.854964432961388, "Epiretinal membrane ": 81.73674680202016, "Febrile neutropenia ": 2.5514577489793666, "Fungal infection ": 7.120198380440874, "Fusarium infection ": 109.73097073532917, "Genital lesion ": 70.14313202692853, "Graft versus host disease ": 25.46792910769731, "Graft versus host disease in gastrointestinal tract ": 19.20732665701491, "Granulocytopenia ": 8.082643050731505, "Haemodynamic instability ": 6.7532442981957965, "Haemophagocytic lymphohistiocytosis ": 19.533609795889223, "Hepatic function abnormal ": 3.481567379843093, "Hepatitis cholestatic ": 3.1528992255001183, "Hepatomegaly ": 3.848120487977617, "Hyperpyrexia ": 2.218929768062478, "Hypomagnesaemia ": 4.873743236638839, "Hypoxia ": 4.639274883002148, "Immune reconstitution inflammatory syndrome ": 9.737013362436642, "Immune thrombocytopenia ": 2.686042786103918, "Intentional product use issue ": 4.597188256118383, "Kidney fibrosis ": 28.75917029524525, "Klebsiella bacteraemia ": 56.73331181658339, "Large intestinal ulcer ": 18.840331831147857, "Leukopenia ": 11.184021713047224, "Liver disorder ": 2.380944135646563, "Lung infiltration ": 4.149060361502943, "Lung opacity ": 8.68872095946977, "Lymphopenia ": 3.5224167646458038, "Metabolic acidosis ": 4.5232319866114725, "Multiple organ dysfunction syndrome ": 11.93025485977306, "Myelosuppression ": 8.681818500258082, "Nephropathy toxic ": 17.35222385259939, "Nephrotic syndrome ": 3.5443542776729555, "Neutropenia ": 7.344611275963463, "Neutrophil Pelger-Huet anomaly present ": 559.0386598035703, "Neutrophil count decreased ": 3.433080153205167, "Off label use ": 4.540881651885303, "Oliguria ": 6.232025790696159, "Oral candidiasis ": 5.375922212651754, "Oxygen saturation decreased ": 2.1666263893054003, "Pancytopenia ": 15.183086190392933, "Pathogen resistance ": 80.30511535194721, "Platelet count decreased ": 2.7301707796880685, "Pneumocystis jirovecii pneumonia ": 17.951250688834016, "Pneumonia bacterial ": 5.285561322354974, "Pneumonia cytomegaloviral ": 96.60966432325596, "Pneumonia fungal ": 19.1127906397976, "Pneumonia lipoid ": 261.0318101212616, "Pneumonia necrotising ": 138.39174146074512, "Post transplant lymphoproliferative disorder ": 27.977122528355924, "Product use in unapproved indication ": 8.146975844656072, "Product use issue ": 12.993841760372671, "Pseudomonas infection ": 12.41252544005707, "Pulmonary hypertension ": 2.3506556572309822, "Renal disorder ": 2.987806319402204, "Renal failure ": 2.20535036530226, "Renal impairment ": 3.130888841537896, "Respiratory failure ": 8.32679428686274, "Retinal degeneration ": 36.80243120887074, "Retinal detachment ": 15.433064259091855, "Retinitis ": 56.1019253052003, "Sepsis ": 4.403691767137607, "Septic shock ": 7.811146700237906, "Shock ": 4.025557232934711, "Staphylococcal infection ": 3.48373986014909, "Systemic mycosis ": 27.389445312530945, "Tachypnoea ": 3.407427283195473, "Thrombocytopenia ": 7.6902376100854015, "Thrombotic microangiopathy ": 57.91471253342652, "Transplant dysfunction ": 32.831780158127145, "Transplant rejection ": 52.58484420039505, "Tubulointerstitial nephritis ": 3.3693175426411206, "Viral load increased ": 15.384479018341914, "Viral mutation identified ": 35.3663445773665, "White blood cell count decreased ": 4.441414615500608}
\ No newline at end of file
+{"Drug ineffective": 4.0002998986946245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/494.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/494.json
index 5af3b3da5a8..3ebb09cb7de 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/494.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/494.json
@@ -1 +1 @@
-{"Ovarian hyperstimulation syndrome ": 2008.8510980136048}
\ No newline at end of file
+{"Acquired gene mutation": 15.660106917405516, "Alopecia": 2.6090831300696906, "Anaemia": 2.4228244499752294, "Ascites": 2.561487870201096, "Aspartate aminotransferase increased": 2.349285571640294, "Blood alkaline phosphatase increased": 2.1544516440103005, "Body height decreased": 4.469288572971133, "Bone cancer": 13.854360592818974, "Bone disorder": 4.5776373201149605, "Bone lesion": 33.432072228914734, "Bone pain": 3.2610779372283605, "Breast cancer": 12.552386066509836, "Breast cancer metastatic": 111.61207427770832, "Breast cancer recurrent": 53.29411403803815, "Breast discharge": 21.597353330191915, "Carbohydrate antigen 15-3 increased": 167.89368010621092, "Carcinoembryonic antigen increased": 45.536884449964, "Cardiomegaly": 2.881062526536045, "Cytopenia": 4.131083408441936, "Decreased immune responsiveness": 20.95656414350695, "Disease progression": 4.452810657340155, "Dry skin": 3.124344516229024, "Eructation": 3.4263555031303867, "Feeding disorder": 2.369405155760438, "Full blood count abnormal": 2.303349306598948, "Full blood count decreased": 3.763892140408255, "Glomerular filtration rate decreased": 2.385440591880667, "Granulocytopenia": 5.263903805858065, "Haematocrit decreased": 4.666604385598965, "Haematotoxicity": 9.397932207284091, "Haemoglobin decreased": 2.333859817595111, "Hepatic failure": 2.0132554080624865, "Hepatic lesion": 9.346337156297665, "Hepatotoxicity": 10.440047326227557, "Hormone receptor positive HER2 negative breast cancer": 267.21994105173206, "Hot flush": 2.465594847265685, "Hydronephrosis": 3.8873554439439415, "Hyperglycaemia": 2.748451120276268, "Injection site necrosis": 8.738115782611867, "Invasive ductal breast carcinoma": 14.673567909379614, "Laboratory test abnormal": 3.21276278350428, "Leukopenia": 6.361071193960198, "Lymphoedema": 7.55837048742187, "Malignant neoplasm progression": 24.744857143348067, "Malignant pleural effusion": 14.24136174074307, "Metastases to bone": 78.40405213224157, "Metastases to breast": 129.83334536743334, "Metastases to central nervous system": 10.43236062766184, "Metastases to chest wall": 65.46013638181599, "Metastases to liver": 52.17818804879387, "Metastases to lung": 30.166543374885133, "Metastases to lymph nodes": 35.73387200321135, "Metastases to pelvis": 33.37026756726263, "Metastases to peritoneum": 18.903484265608824, "Metastases to pleura": 58.40811912332766, "Metastases to skin": 22.285745882372048, "Metastases to spine": 45.345687725419175, "Metastases to the mediastinum": 49.88382143570621, "Metastases to thorax": 182.29646371445895, "Metastasis": 23.47055048563306, "Metastatic neoplasm": 12.258242032138185, "Mucosal inflammation": 4.879185308676102, "Musculoskeletal discomfort": 3.442372112815428, "Myelosuppression": 2.101580496075043, "Neoplasm progression": 27.257677901187712, "Neutropenia": 21.20655330025302, "Neutrophil count decreased": 7.10703588118185, "Nodule": 2.27846538440165, "Osteolysis": 16.75248395665225, "Osteonecrosis of jaw": 10.94710654114688, "Osteosclerosis": 28.431878535116777, "PIK3CA-activated mutation": 127.9572508703418, "Platelet count decreased": 2.7578630279872627, "Platelet count increased": 2.1711819721110968, "Pleural effusion": 4.107926996415568, "Pneumonitis": 2.8614968034522104, "Product dose omission in error": 6.373068747178346, "Pulmonary mass": 5.036649763590992, "Red blood cell count decreased": 4.045702736729371, "Second primary malignancy": 2.632643487887668, "Spinal pain": 5.986003486377823, "Staphylococcal infection": 2.446841323255497, "Therapy partial responder": 9.388942977353189, "Thrombocytopenia": 3.146575955501578, "Thrombophlebitis": 5.550895742559134, "Tooth fracture": 3.355686490705604, "Transaminases increased": 2.559168952863428, "Tumour marker increased": 54.699471354369024, "White blood cell count decreased": 4.07058946271166}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/495.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/495.json
index 8dbf7248848..3b526d504ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/495.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/495.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.184502074062689, "Abdominal pain lower ": 3.4012786098137373, "Abnormal loss of weight ": 2.2635609413244744, "Abortion induced ": 11.804580931956572, "Abortion missed ": 3.5810030082947564, "Abortion spontaneous ": 4.204782983496123, "Acne ": 4.271315468787484, "Acute disseminated encephalomyelitis ": 22.16354484870209, "Acute sinusitis ": 5.391267294317867, "Adenocarcinoma of the cervix ": 54.1932788499651, "Adverse event ": 3.220604709138017, "Adverse event following immunisation ": 25.915461537995174, "Alcohol intolerance ": 3.997143694867675, "Allergy to animal ": 5.06044881761342, "Allergy to vaccine ": 11.178778725263795, "Allodynia ": 8.299626783196151, "Alopecia areata ": 2.779844396609774, "Amniotic cavity infection ": 4.142644689710695, "Amplified musculoskeletal pain syndrome ": 145.51225347647076, "Amyotrophic lateral sclerosis ": 2.941585496084374, "Angiopathy ": 3.550093183006948, "Anogenital warts ": 72.65606894254631, "Anorexia nervosa ": 10.72942061592284, "Anti-thyroid antibody ": 18.15384972895468, "Anti-thyroid antibody positive ": 4.171913179417255, "Antibody test negative ": 4.818781612933058, "Antinuclear antibody positive ": 3.7864937317592338, "Antiphospholipid syndrome ": 6.271562033230672, "Anxiety disorder ": 3.542877015599678, "Anxiety disorder due to a general medical condition ": 52.9345240341982, "Appendicectomy ": 6.2699308076641325, "Areflexia ": 4.340270932646788, "Arnold-Chiari malformation ": 4.486955127273264, "Arrested labour ": 17.059728529030046, "Arthritis reactive ": 4.487941083354287, "Asthma exercise induced ": 30.20561878252772, "Astigmatism ": 2.9041705346459343, "Ataxia ": 2.372710911892667, "Atonic seizures ": 3.1818444584995884, "Attention deficit hyperactivity disorder ": 4.851267571153799, "Autoimmune disorder ": 9.804258908793251, "Autoimmune encephalopathy ": 27.682357980940907, "Autoimmune neuropathy ": 15.68810972734583, "Autoimmune thyroiditis ": 6.604799007513588, "Autonomic nervous system imbalance ": 31.91917461103637, "Autonomic neuropathy ": 23.450875887580985, "Bacterial vaginosis ": 5.636362887135623, "Bacterial vulvovaginitis ": 18.941074702803203, "Bartonellosis ": 79.02833825866827, "Bedridden ": 2.327442938541424, "Beta haemolytic streptococcal infection ": 6.578791146617865, "Blindness transient ": 3.7372711912742287, "Blood aluminium increased ": 27.869754761488355, "Blood glucose normal ": 46.021967412803335, "Blood test ": 5.465525774160485, "Blood urea decreased ": 2.9716137295692797, "Body temperature fluctuation ": 4.574679359891302, "Bone tuberculosis ": 10.29040971684035, "Borderline personality disorder ": 8.0695702875848, "Breast discharge ": 4.038560196684616, "Breech presentation ": 11.104111477924382, "Bronchial hyperreactivity ": 2.169827093298637, "Bruxism ": 2.714721268938394, "Caesarean section ": 2.726917553068876, "Carbon dioxide decreased ": 3.3159886533305967, "Carcinoma in situ ": 46.591445822586, "Cataplexy ": 24.5973379204542, "Central nervous system inflammation ": 9.508103438573952, "Central nervous system vasculitis ": 3.7601409626398254, "Cerebellar ataxia ": 3.200512348781104, "Cerebral circulatory failure ": 46.8022731247579, "Cervical conisation ": 240.088482691558, "Cervical dysplasia ": 222.5649834247455, "Cervicitis ": 20.396950832593944, "Cervicobrachial syndrome ": 3.1818444584995884, "Cervix carcinoma ": 25.623608003271865, "Cervix carcinoma stage 0 ": 171.54689905781538, "Cervix disorder ": 21.18155176500074, "Chorea ": 2.1317744436119708, "Chronic fatigue syndrome ": 16.984119810590094, "Chronic inflammatory demyelinating polyradiculoneuropathy ": 2.72362327558573, "Circadian rhythm sleep disorder ": 6.40968737843045, "Clonic convulsion ": 2.81011381527032, "Clonus ": 3.666290331002765, "Cognitive disorder ": 4.309543260610299, "Cold sweat ": 2.122695767082145, "Complex regional pain syndrome ": 24.36070927443529, "Complication of delivery ": 25.68297293376917, "Computerised tomogram normal ": 47.5232163302004, "Concussion ": 7.596917342288229, "Connective tissue disorder ": 7.184985016512057, "Consciousness fluctuating ": 2.911629417832572, "Conversion disorder ": 21.537297112312565, "Coxsackie viral infection ": 24.228647034438715, "Culture urine positive ": 6.300343591545618, "Cystitis interstitial ": 3.785367848051517, "Dairy intolerance ": 13.313539013643542, "Decreased activity ": 2.321012922317694, "Decreased immune responsiveness ": 2.943925815988416, "Demyelination ": 11.827197393323337, "Derealisation ": 2.5345590122725574, "Dermal cyst ": 2.9716137295692797, "Dermatomyositis ": 2.425912937723406, "Diplegia ": 7.928637210571082, "Diplopia ": 2.1760861979223804, "Dissociative disorder ": 9.51126433642105, "Disturbance in attention ": 4.567871360238483, "Dizziness ": 2.31921778540995, "Dizziness postural ": 2.8182796627603803, "Drooling ": 2.0679736900465224, "Drowning ": 3.357622485606285, "Drug exposure before pregnancy ": 5.386528222966223, "Dysaesthesia ": 3.5214856124315714, "Dyskinesia ": 5.982727196062557, "Dyspareunia ": 10.603316960373816, "Dysplasia ": 7.573681381639845, "Dysstasia ": 2.2114067362863983, "Dysuria ": 2.680385824809301, "Ectopic pregnancy ": 2.4706034617320998, "Ehlers-Danlos syndrome ": 72.2150223153652, "Electrocardiogram T wave abnormal ": 6.768431223725661, "Encephalitis ": 6.225442000031031, "Encephalitis autoimmune ": 5.243879314143949, "Encephalitis post immunisation ": 25.140718493747272, "Encephalitis viral ": 2.555811670245405, "Encephalomyelitis ": 11.833981075332511, "Endometriosis ": 7.821178586733486, "Eosinophilic oesophagitis ": 9.935904510541976, "Epilepsy ": 2.526118706123407, "Epstein-Barr virus infection ": 3.587175413086636, "Erythema nodosum ": 3.046760942743399, "Essential tremor ": 3.599686820589099, "Eustachian tube dysfunction ": 5.684287021508732, "Exercise tolerance decreased ": 4.873134633713202, "Exposure during pregnancy ": 6.714412803950575, "Eye movement disorder ": 10.217407710713417, "Eyelid function disorder ": 4.20169660850503, "Face injury ": 4.792482205430915, "Facial paralysis ": 2.1577155711032687, "Facial paresis ": 3.676057971027796, "Facial spasm ": 3.9651869570284375, "Failed trial of labour ": 88.78244063081932, "Fear of injection ": 2.758993614797749, "Fibroadenoma of breast ": 6.6079039566281255, "Fibromyalgia ": 3.5640499589806574, "Focal dyscognitive seizures ": 2.3153184668312807, "Foetal heart rate abnormal ": 4.446274376300782, "Foetal heart rate deceleration abnormality ": 3.2437543729757685, "Food allergy ": 4.997603417966292, "Food intolerance ": 8.632601510921315, "Full blood count ": 12.471320486033791, "Full blood count normal ": 33.72115178371756, "Gait inability ": 2.527331687040578, "Gastroenteritis ": 2.07822184601995, "Gastrointestinal bacterial overgrowth ": 9.269911676393484, "Gastrointestinal motility disorder ": 2.099541604819133, "Gaze palsy ": 4.161020548772105, "General symptom ": 3.753457570897822, "Generalised anxiety disorder ": 12.27009129444493, "Generalised tonic-clonic seizure ": 3.695166276212011, "Genito-pelvic pain/penetration disorder ": 35.76787976752307, "Gestational hypertension ": 2.809742312328228, "Gluten sensitivity ": 16.407748403799914, "Granuloma ": 2.058729047525755, "Grunting ": 5.4154000492976, "Guillain-Barre syndrome ": 8.890485041552422, "Haemorrhagic ovarian cyst ": 8.90084121236159, "Head injury ": 5.776231490997012, "Henoch-Schonlein purpura ": 6.845010088781863, "Hidradenitis ": 2.876777436521344, "Hirsutism ": 2.257764834363822, "Hodgkin's disease ": 3.678976217053104, "Hormone level abnormal ": 2.360556084434402, "Human papilloma virus test positive ": 658.4496585751372, "Hyperacusis ": 14.740686373023308, "Hyperaesthesia ": 2.4441828976645663, "Hypermetropia ": 3.968422311759035, "Hypermobility syndrome ": 34.5737603775742, "Hypersomnia ": 4.776761134435052, "Hypertonic bladder ": 3.698041584363723, "Hyperventilation ": 10.850281370163048, "Hypoaesthesia ": 2.8673290603280543, "Hyporeflexia ": 4.060867572764426, "Hypotonia ": 2.1086709497718603, "Idiopathic intracranial hypertension ": 4.383536482427187, "Illusion ": 4.387385125561347, "Immediate post-injection reaction ": 62.68624457740534, "Immune system disorder ": 4.16992911048345, "Immune thrombocytopenia ": 2.810102750169865, "Immunodeficiency common variable ": 12.967196997188552, "Immunoglobulin therapy ": 44.90256802070202, "Impaired gastric emptying ": 5.598179826764711, "Impaired work ability ": 3.219887370171268, "Impetigo ": 2.434518211837626, "Inappropriate schedule of product administration ": 3.5903435834293447, "Incomplete course of vaccination ": 4.899971239737133, "Incorrect route of product administration ": 2.1604787777969023, "Increased tendency to bruise ": 3.3752282841523056, "Induration ": 3.849267172718184, "Infection susceptibility increased ": 4.791435754704932, "Infectious mononucleosis ": 21.47945737499857, "Infertility ": 8.486809905560957, "Infertility female ": 7.587488265601696, "Inflammatory bowel disease ": 2.12177509232735, "Initial insomnia ": 2.699538546551396, "Injected limb mobility decreased ": 2.321739191336306, "Injection site irritation ": 3.071041323548865, "Injection site paraesthesia ": 2.2674519405757576, "Insulin resistance ": 2.472983569635918, "Intensive care ": 10.340098354904514, "Iron deficiency ": 2.7022190776147137, "Iron deficiency anaemia ": 2.1084246897166388, "Irritable bowel syndrome ": 2.4528970980124982, "Joint dislocation ": 2.0492379273751333, "Joint hyperextension ": 11.915493764137414, "Joint lock ": 4.4892970446945055, "Joint noise ": 3.4018527997399164, "Juvenile idiopathic arthritis ": 9.383357027318214, "Juvenile myoclonic epilepsy ": 64.7540181829206, "Labour complication ": 66.52434329736816, "Lactose intolerance ": 6.460965124056082, "Laryngeal pain ": 12.417265225085814, "Learning disability ": 2.624044532511292, "Learning disorder ": 2.857511896507905, "Leukoencephalomyelitis ": 132.95789170707545, "Ligament sprain ": 2.636477003373537, "Lip injury ": 5.0152810186693495, "Livedo reticularis ": 3.2144602592322165, "Lordosis ": 8.371365617444159, "Loss of consciousness ": 4.469268674356597, "Loss of control of legs ": 2.9039571759100617, "Lumbar puncture ": 15.272774129780249, "Lupus nephritis ": 2.612345366539917, "Lyme disease ": 10.666414880869382, "Magnetic resonance imaging head abnormal ": 2.2496140464684977, "Major depression ": 2.5541108282856504, "Mast cell activation syndrome ": 19.37366384462523, "Maternal exposure before pregnancy ": 5.572073221524352, "Melanocytic naevus ": 2.052637310544196, "Memory impairment ": 2.820406397776104, "Meningism ": 5.627798572035309, "Meningitis viral ": 3.2392127816267102, "Mesenteric lymphadenitis ": 12.166718115190466, "Metal poisoning ": 21.41090238761431, "Methylenetetrahydrofolate reductase gene mutation ": 132.95789170707545, "Migraine ": 2.355015301968417, "Migraine with aura ": 3.4332702480461625, "Migraine without aura ": 9.275656764706726, "Miller Fisher syndrome ": 4.201598200555135, "Mixed anxiety and depressive disorder ": 2.7332632117912112, "Mixed connective tissue disease ": 10.969720467285828, "Monoparesis ": 3.207761190666808, "Monoplegia ": 5.566736809569423, "Motion sickness ": 4.564294642739241, "Mouth injury ": 2.559722159869604, "Multiple sclerosis ": 7.000328285493678, "Muscle contractions involuntary ": 2.450452707286093, "Muscle contracture ": 2.1030527772341507, "Muscle rigidity ": 2.295670642580961, "Muscle tightness ": 2.9787755721043467, "Muscle twitching ": 3.192684277248285, "Muscular weakness ": 4.461509714841062, "Mycoplasma infection ": 16.890791795422807, "Myelitis ": 5.051379494696148, "Myelitis transverse ": 10.712938448215867, "Myoclonic epilepsy ": 2.0193118932054994, "Myofascial pain syndrome ": 6.330061632747766, "Myofascitis ": 25.647032322582945, "Narcolepsy ": 23.67095228854161, "Neck pain ": 2.330338741475777, "Nervous system disorder ": 2.8370247140589893, "Neurogenic bladder ": 4.093308835175206, "Neurological symptom ": 2.9425877240799285, "Neuromyelitis optica spectrum disorder ": 5.663523013688188, "Neuromyopathy ": 2.4396592543916027, "No adverse event ": 3.887933854760525, "Noninfective encephalitis ": 7.371081007566778, "Nystagmus ": 2.010269425713638, "Obsessive-compulsive disorder ": 2.858695349858913, "Opisthotonus ": 2.504018289459586, "Optic neuritis ": 6.166319942328212, "Orthostatic intolerance ": 108.22267915678968, "Otitis externa ": 3.267371003436215, "Otitis media acute ": 6.424575725180661, "Ovarian cyst ": 7.271329271376039, "Ovarian cyst ruptured ": 9.585506318345404, "Ovarian failure ": 17.649250192178776, "Pallor ": 9.188264992769335, "Papilloma viral infection ": 136.76112806333907, "Paralysis ": 6.948879687817077, "Paraparesis ": 60.87283161650386, "Paraplegia ": 2.8724471925193984, "Paresis ": 4.392160465170734, "Pelvic inflammatory disease ": 7.775901971141212, "Pelvic pain ": 2.351586182780637, "Peripheral coldness ": 4.1912639708944885, "Peripheral paralysis ": 8.092680980914258, "Peripheral vascular disorder ": 3.770380738095266, "Personality change ": 2.1388317055107806, "Petit mal epilepsy ": 2.7736409903945827, "Pharyngeal erythema ": 2.415028433920557, "Pharyngitis ": 3.817038147783936, "Pharyngitis streptococcal ": 5.188792845996884, "Phonophobia ": 8.609841751386828, "Photophobia ": 7.178833634746916, "Pineal gland cyst ": 31.89632822653764, "Pityriasis rosea ": 3.54756628266662, "Polyarthritis ": 2.7289772784054187, "Polycystic ovarian syndrome ": 22.053125387903727, "Polymyositis ": 2.072305104696043, "Post vaccination syndrome ": 3.322719634718234, "Post-traumatic stress disorder ": 2.764295341272708, "Postictal state ": 6.998001069471346, "Postural orthostatic tachycardia syndrome ": 89.93581689493419, "Posture abnormal ": 8.586208258678164, "Pre-eclampsia ": 3.0442574078627533, "Premature labour ": 2.631775490923829, "Premature menopause ": 16.00694302108516, "Premature rupture of membranes ": 2.2741795034101595, "Presyncope ": 5.7534832119186845, "Product administered at inappropriate site ": 3.547148327329185, "Product administered to patient of inappropriate age ": 2.633318660205244, "Product lot number issue ": 42.803307723476735, "Product name confusion ": 7.150586329123432, "Product origin unknown ": 63.06277500021524, "Psychogenic seizure ": 8.852669974974052, "Raynaud's phenomenon ": 3.866568026699421, "Reading disorder ": 3.653497583362144, "Reflux gastritis ": 2.867914524971113, "Relapsing-remitting multiple sclerosis ": 7.419074552804084, "Respiratory distress ": 2.1280458582157817, "Sacroiliitis ": 4.098291570171042, "School refusal ": 37.88538870542823, "Scoliosis ": 3.064880378955511, "Seasonal allergy ": 2.0593722454874515, "Seizure ": 4.150246637273334, "Seizure like phenomena ": 13.101988054353564, "Self esteem decreased ": 3.197060104500168, "Sensory disturbance ": 5.816793233418414, "Sensory level abnormal ": 2.025440118718391, "Sensory loss ": 3.359104150906897, "Serum ferritin decreased ": 3.985084809183125, "Serum sickness ": 3.4222455352845254, "Sinus arrhythmia ": 4.011747036133462, "Sjogren's syndrome ": 2.0507832578007363, "Skin laceration ": 2.081268315813245, "Skin papilloma ": 5.957155275798578, "Skin striae ": 10.109748111838549, "Skull fracture ": 4.728530957616817, "Sleep disorder ": 2.472838215558343, "Small fibre neuropathy ": 8.297698284434189, "Small for dates baby ": 3.3728275618111363, "Smear cervix abnormal ": 96.01306276343556, "Smear cervix normal ": 294.7495062299504, "Social avoidant behaviour ": 4.90207343166977, "Somatic symptom disorder ": 15.360080516056057, "Staring ": 6.79695711062048, "Still's disease ": 2.8314761302845426, "Streptococcus test positive ": 6.955982603534175, "Substance use ": 3.1297115722718534, "Syncope ": 10.00299991856321, "Temperature intolerance ": 2.534298848519278, "Temperature regulation disorder ": 3.3714104182582108, "Tension headache ": 2.118309119424083, "Tetany ": 4.741035066336757, "Thrombocytopenic purpura ": 2.1534052927377694, "Tic ": 6.941868560183478, "Tongue biting ": 3.2083603613432325, "Tonic clonic movements ": 27.801345092527264, "Tonic convulsion ": 3.0766820110088275, "Tonsillectomy ": 4.62571182282145, "Tonsillitis ": 3.8434976311010542, "Type 1 diabetes mellitus ": 3.632634075617855, "Type III immune complex mediated reaction ": 4.682837326379925, "Underweight ": 2.4842726759569738, "Unresponsive to stimuli ": 3.2682859686038674, "Urinary incontinence ": 2.2921957299204183, "Vaccination complication ": 13.765638125900646, "Vaccination error ": 11.796504318858885, "Vaccination site cellulitis ": 10.109298148657416, "Vaccination site granuloma ": 5.39448124161537, "Vaccination site haemorrhage ": 2.211264244502202, "Vaccination site nodule ": 8.801688959630235, "Vaccine positive rechallenge ": 88.77815959694844, "Vascular malformation ": 11.40501691928078, "Viral infection ": 4.218242778195194, "Vision blurred ": 2.0010283589405917, "Vitamin B12 deficiency ": 2.192588415701701, "Vitamin D decreased ": 2.600567244642193, "Walking disability ": 2.061062885187697, "Wheelchair user ": 5.163870363645093}
\ No newline at end of file
+{"Alanine aminotransferase increased": 11.460503571753144, "Aspartate aminotransferase increased": 10.08115173824039, "Cholestasis": 30.52912981358692, "Granulomatous liver disease": 906.3244014727634, "Hepatic encephalopathy": 61.340033465269, "Hepatitis fulminant": 196.6941678065769, "Immune reconstitution inflammatory syndrome": 122.55659360463837, "Insomnia": 4.998444574232191, "Jaundice": 13.111238054977, "Leukopenia": 6.815242905654048, "Lymphopenia": 42.21135955493028, "Neutropenia": 3.099993171355328, "Pneumonia": 2.4793974479225422, "Renal failure": 4.777526412678703, "Tachypnoea": 34.83688039408922, "Tuberculosis liver": 7613.25089238314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/496.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/496.json
index 654c3dbba84..9da447dd226 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/496.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/496.json
@@ -1 +1 @@
-{"Asthenia ": 3.0230706475365565, "Blood pressure increased ": 2.729743293333726, "Constipation ": 4.832476487321132, "Disease progression ": 4.597574737685297, "Haemoglobin decreased ": 5.329737906351069, "Hypertension ": 2.4760055626867725, "Interstitial lung disease ": 4.413154285043648, "Myelosuppression ": 4.963177993943318, "Platelet count decreased ": 4.198244499545837, "Pneumonia ": 2.210008769813186, "White blood cell count decreased ": 8.64198337776074}
\ No newline at end of file
+{"Abnormal behaviour": 6.167782667245704, "Accidental overdose": 3.253932905014447, "Acute pulmonary oedema": 7.313833577725554, "Aggression": 54.633926663663935, "Agitation": 6.742071344111657, "Altered state of consciousness": 5.8775045454376045, "Amnesia": 2.469953105065148, "Anger": 25.77277814290632, "Anticonvulsant drug level increased": 37.00809436042189, "Apathy": 4.520259805327356, "Ataxia": 14.899451907782906, "Aura": 22.55356930889413, "Balance disorder": 6.42614955601004, "Behaviour disorder": 12.374557642448412, "Cognitive disorder": 5.50257768510383, "Confusional state": 2.0225248441151784, "Crying": 3.5096254075168702, "Delirium": 2.337125726675548, "Delusion": 10.619229147939722, "Depressed mood": 3.606328785464148, "Depression": 2.5250618784263463, "Diplopia": 5.439592715976101, "Disturbance in attention": 2.109607166475475, "Drug eruption": 4.319073140031302, "Drug interaction": 3.9101719069636114, "Drug level decreased": 11.044919091057174, "Drug withdrawal convulsions": 30.46257916292862, "Drug-induced liver injury": 4.539919259958051, "Dysarthria": 7.500747393907536, "Dyskinesia": 3.749273033091782, "Emotional disorder": 3.707431638699628, "Encephalopathy": 2.860885076501177, "Epilepsy": 9.16621615839612, "Erectile dysfunction": 4.650333661325357, "Euphoric mood": 12.61722814648986, "Exfoliative rash": 17.966812824868196, "Exposure during pregnancy": 2.960218242025225, "Fall": 3.088161736864961, "Focal dyscognitive seizures": 64.32892925188159, "Gait disturbance": 5.530931078015678, "Gaze palsy": 27.749640592152737, "General physical health deterioration": 3.4681400779768103, "Generalised tonic-clonic seizure": 5.354562078945678, "Hallucination": 3.0691786676542123, "Hallucination, auditory": 5.23944941306573, "Hallucination, visual": 6.176800216476574, "Head injury": 6.676504151030104, "Heart rate irregular": 3.795845124338, "Hepatic cytolysis": 2.4883904648832336, "Homicidal ideation": 58.91360866932415, "Hostility": 23.94001159076202, "Hyperammonaemia": 8.345077691863196, "Hypersomnia": 2.383497799806398, "Hypothermia": 11.451326894691636, "Hypotonia": 2.877426480812209, "Increased appetite": 4.068681134055331, "Intentional overdose": 6.698387422911089, "Irritability": 23.39228841290309, "Liver injury": 3.229319690224901, "Mental status changes": 2.8803371331903262, "Mitral valve disease": 34.563785348141884, "Mood altered": 12.627323155305202, "Multiple-drug resistance": 81.50660345662867, "Nervousness": 2.674890638713748, "Paranoia": 5.685450323534483, "Partial seizures": 23.135567874753814, "Persecutory delusion": 17.46253025377572, "Personality change": 13.786134240113562, "Petit mal epilepsy": 9.475416310747857, "Physical assault": 70.48429610073784, "Pneumonia aspiration": 5.604614723136496, "Product administered to patient of inappropriate age": 6.763873098312874, "Psychiatric symptom": 8.522408418008784, "Psychomotor hyperactivity": 4.175707236722924, "Psychotic disorder": 16.435413817933814, "Restlessness": 5.022475043473767, "Salivary hypersecretion": 4.643966189416276, "Sedation": 2.2902415693451306, "Seizure": 9.314815364186952, "Self-destructive behaviour": 9.94347716623241, "Skin lesion": 2.007819986359565, "Slow speech": 33.280715340706934, "Somnolence": 6.647211096520892, "Staphylococcus test positive": 30.773475985095885, "Status epilepticus": 26.01142895891065, "Sudden unexplained death in epilepsy": 107.67430235135168, "Suicidal ideation": 8.418510214846759, "Suicide attempt": 12.30075627524149, "Toxic epidermal necrolysis": 5.53517838660358, "Urinary retention": 2.9912568767672965, "Vertigo": 4.485276549107328, "Weight increased": 3.709066018644176, "Wrong patient received product": 17.40906569057788}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/497.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/497.json
index e44aa13ee2e..a11f085e319 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/497.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/497.json
@@ -1 +1 @@
-{"Agranulocytosis ": 4.248517937858285, "Blood lactate dehydrogenase increased ": 5.683274155706481, "Blood pressure decreased ": 2.399455010322553, "Bronchospasm ": 4.758965037954392, "Chronic lymphocytic leukaemia recurrent ": 153.9177200122778, "Cytokine release syndrome ": 7.439178634620165, "Cytopenia ": 9.674967489012186, "Disease progression ": 3.8285437968358393, "Febrile neutropenia ": 3.821791946146434, "Flushing ": 3.347854905861323, "Follicular lymphoma ": 82.14643210998236, "Hepatic cytolysis ": 8.076937563672756, "Hepatitis ": 2.020561315200754, "Hyperhidrosis ": 2.236148330981218, "Hypertransaminasaemia ": 5.860827136769324, "Hypotension ": 4.517922185532386, "Hypoxia ": 2.6807289258052616, "Ill-defined disorder ": 2.460101203810525, "Infection ": 2.8107207937120644, "Infusion related reaction ": 46.704607631476414, "Intentional product use issue ": 6.243268441841447, "Leukopenia ": 6.63119853651579, "Liver function test abnormal ": 2.197509857588608, "Lymphocyte count decreased ": 11.794093682792798, "Lymphopenia ": 10.1813265001177, "Neutropenia ": 15.80752821067424, "Neutropenic sepsis ": 16.682693453617606, "Off label use ": 2.362484445409136, "Oxygen saturation decreased ": 4.756680736940636, "Pancytopenia ": 3.1488774714946244, "Platelet count decreased ": 4.223588009009061, "Progressive multifocal leukoencephalopathy ": 61.29121853312946, "Respiratory distress ": 2.094093299040895, "Respiratory failure ": 2.448010234914632, "Respiratory tract infection ": 10.827224774667783, "Sepsis ": 3.75867993528057, "Septic shock ": 3.751810518334477, "Splenomegaly ": 5.186336641566154, "Thrombocytopenia ": 10.331459565471992, "Transaminases increased ": 5.2146579646320905, "Tumour lysis syndrome ": 111.77361695970691, "White blood cell count decreased ": 3.625977881056468}
\ No newline at end of file
+{"Adverse event": 4.02219839339429, "Atrial fibrillation": 2.5556926464388265, "Cardiac disorder": 4.501018091845299, "Cerebrovascular accident": 4.285635311507412, "Depressed mood": 2.050213171226122, "Depression": 2.416578072400478, "Dyspepsia": 2.408050438087031, "Flatulence": 3.17188018200651, "Gastrointestinal disorder": 2.948208807080858, "Glomerular filtration rate decreased": 21.12201785750508, "Hospitalisation": 3.4804074557423306, "Impaired work ability": 5.213511559014525, "Implantable defibrillator insertion": 95.1580602402994, "Inappropriate schedule of product administration": 4.172117018832758, "Nasal congestion": 2.8220767946630883, "Nephrolithiasis": 4.086116711126249, "Neuropathy peripheral": 4.080614936935806, "Poor quality sleep": 11.020034157197278, "Pre-existing condition improved": 171.6906000939662, "Product dose omission in error": 44.89261774555358, "Product dose omission issue": 13.547254056044514, "Product physical issue": 22.632470588815448, "Proteinuria": 10.428904441011738, "Renal disorder": 2.8780641748972275, "Renal impairment": 3.52735308160889, "Rhinorrhoea": 5.519666429598175, "Sinusitis": 2.801534104790178, "Surgery": 4.916651430912984, "Temperature intolerance": 21.084889731617096, "Transient ischaemic attack": 5.38140934991934, "Weight increased": 2.4688031127314165, "Wrong technique in product usage process": 2.434036577458104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/498.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/498.json
index 03ceefd10a9..6c6de2a42fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/498.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/498.json
@@ -1 +1 @@
-{"Acquired gene mutation ": 1332.9235146927251, "Alanine aminotransferase increased ": 2.94912070123708, "Aspartate aminotransferase increased ": 2.2138362594757086, "Dermatitis acneiform ": 51.80496949539893, "Diarrhoea ": 2.5027644868259267, "Disease progression ": 8.704496992032258, "Drug interaction ": 2.170150005911798, "Drug resistance ": 149.64231670061238, "Drug-induced liver injury ": 6.502114492984986, "EGFR gene mutation ": 3703.5645799823487, "Gene mutation ": 76.17624291310764, "Hepatic function abnormal ": 6.852372897748949, "Hepatotoxicity ": 12.271814291520244, "Interstitial lung disease ": 15.91222092680261, "Left ventricular dysfunction ": 13.46179432791123, "Liver function test abnormal ": 5.501414530026557, "Liver injury ": 5.327021095731904, "Lung adenocarcinoma ": 47.32440281927434, "Lung adenocarcinoma stage IV ": 369.3220082985871, "Malignant neoplasm progression ": 51.87421790053863, "Malignant transformation ": 2091.4869565741496, "Metastases to bone ": 35.13422829398389, "Metastases to central nervous system ": 137.6437376626633, "Metastases to liver ": 24.86186010700512, "Metastases to lung ": 36.13115434155291, "Metastases to lymph nodes ": 20.77716717434163, "Metastases to meninges ": 393.0899666966118, "Metastasis ": 23.41666785477021, "Myelosuppression ": 2.814276526251704, "Non-small cell lung cancer ": 28.23458809957795, "Pancreatitis acute ": 3.5635039625955947, "Paronychia ": 87.68899063871469, "Pericardial effusion ": 3.7159938383499753, "Pleural effusion ": 7.3092818920871, "Pneumonitis ": 4.128659506926195, "Pulmonary mass ": 6.943093835059006, "Rash ": 3.1164285753662577, "Rash pruritic ": 2.988448749588748, "Rash pustular ": 14.735475412541208, "Respiratory failure ": 2.753170958813442, "Skin toxicity ": 48.854939917171336, "Small cell lung cancer ": 241.04846799687147, "Transaminases increased ": 4.3834987735786095}
\ No newline at end of file
+{"Abdominal distension": 2.4300998163370098, "Abdominal pain upper": 2.3880852595388298, "Alanine aminotransferase increased": 4.267638512154704, "Amylase increased": 22.12117026435505, "Angioedema": 3.2178620994794027, "Anuria": 3.4127886797724782, "Aspartate aminotransferase increased": 4.079011524832071, "Blister": 3.7927530296568377, "Blood alkaline phosphatase increased": 2.671859185458933, "Blood bilirubin increased": 2.442059093627207, "Blood cholesterol increased": 2.007822744440191, "Blood glucose abnormal": 4.3753127507365885, "Blood glucose decreased": 2.4107447343819155, "Blood glucose fluctuation": 7.824770180694904, "Blood glucose increased": 12.033739859087891, "Blood triglycerides increased": 5.635058455934962, "Blood urea increased": 3.4182265517851174, "Cardiac failure": 3.014263694081576, "Cataract": 2.304629544801021, "Cholelithiasis": 7.079927220126869, "Cholestasis": 5.324503364868519, "Chromaturia": 2.937058308108096, "Dermatitis bullous": 23.033626864547927, "Diabetes mellitus": 5.56163518198829, "Diabetes mellitus inadequate control": 9.679251838798468, "Dry throat": 5.062486347422186, "Dysphagia": 2.181611824716457, "Eczema": 4.106727674208305, "Encephalopathy": 2.812879986650642, "Face oedema": 2.0411462221419048, "Fall": 2.664782049824905, "Fear": 2.9662039537034484, "Femur fracture": 4.533766502952226, "Gait inability": 2.100018584079771, "Gamma-glutamyltransferase increased": 8.287586051827768, "Gastritis": 2.2680861508945926, "Generalised oedema": 3.3993588128725567, "Glycosylated haemoglobin increased": 13.781345171413143, "Hepatic cytolysis": 5.878499414188664, "Hepatic steatosis": 9.957790632863446, "Hepatitis": 3.4170211818400245, "Hyperglycaemia": 3.734379853463407, "Hypertension": 2.095050733522311, "Hypoglycaemia": 6.818774378895648, "Hypoglycaemic coma": 2.7056240675604366, "Incorrect dose administered": 2.521487928285102, "Jaundice": 5.054777640387836, "Lactic acidosis": 2.8820989665033085, "Limb injury": 2.7727102958813195, "Lipase increased": 26.767249508577606, "Liver function test abnormal": 2.3852231979372447, "Lower limb fracture": 3.388460787807487, "Oedema peripheral": 2.7991882536292065, "Osteoarthritis": 2.869443626100271, "Pancreatic carcinoma": 4.491101435650726, "Pancreatitis": 9.400287012389944, "Pancreatitis acute": 13.376712239629532, "Pemphigoid": 91.55724317758154, "Pruritus": 2.090225813022224, "Pulmonary oedema": 2.3182526254572164, "Renal disorder": 3.575384537404418, "Skin exfoliation": 3.786259498493602, "Transaminases increased": 4.639425276135963}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/499.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/499.json
index 3db2c04c0ee..3b8c582b785 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/499.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/499.json
@@ -1 +1 @@
-{"Exposure during pregnancy ": 10.110248300423528, "Hypotonia ": 38.236220074488855}
\ No newline at end of file
+{"Acute graft versus host disease": 8.473399684785521, "Acute kidney injury": 2.913212315839871, "Acute respiratory distress syndrome": 6.5106134136318365, "Agranulocytosis": 4.13365249352052, "Aspergillus infection": 6.04004687555517, "Bone marrow failure": 13.67011843057223, "Bronchiectasis": 6.120267609181379, "Bronchopulmonary aspergillosis": 18.756910583858662, "Cardiogenic shock": 3.7547533692140367, "Cholestasis": 2.407620749303092, "Clostridium difficile colitis": 4.737792072897808, "Coagulopathy": 2.730106209427165, "Colitis": 2.268487688612998, "Condition aggravated": 2.089118306521664, "Cytomegalovirus chorioretinitis": 149.11839336348416, "Cytomegalovirus colitis": 163.57203200345444, "Cytomegalovirus enteritis": 140.93962494464978, "Cytomegalovirus enterocolitis": 49.528379822420405, "Cytomegalovirus gastritis": 168.0671433188008, "Cytomegalovirus hepatitis": 132.7945815142211, "Cytomegalovirus infection": 60.69375850001629, "Cytomegalovirus infection reactivation": 86.31765211281565, "Cytomegalovirus syndrome": 473.6931449373272, "Cytomegalovirus test positive": 14.490029374334371, "Cytomegalovirus viraemia": 174.12577136506067, "Cytopenia": 15.086489811961677, "Depressed level of consciousness": 3.6070946670252138, "Disseminated cytomegaloviral infection": 406.71840639623866, "Drug ineffective": 3.0927586416348145, "Drug ineffective for unapproved indication": 8.909125511865607, "Drug reaction with eosinophilia and systemic symptoms": 4.233071746565882, "Drug resistance": 64.03121628065877, "Encephalitis cytomegalovirus": 342.37811265980645, "Encephalopathy": 3.9401389606454673, "Enterococcal infection": 15.854964432961388, "Epiretinal membrane": 81.73674680202016, "Febrile neutropenia": 2.5514577489793666, "Fungal infection": 7.118218398976823, "Fusarium infection": 109.73097073532917, "Genital lesion": 70.14313202692853, "Graft versus host disease": 25.46792910769731, "Graft versus host disease in gastrointestinal tract": 19.20732665701491, "Granulocytopenia": 8.080309076734414, "Haemodynamic instability": 6.7532442981957965, "Haemophagocytic lymphohistiocytosis": 19.533609795889223, "Hepatic function abnormal": 3.481567379843093, "Hepatitis cholestatic": 3.1528992255001183, "Hepatomegaly": 3.848120487977617, "Hyperpyrexia": 2.218929768062478, "Hypomagnesaemia": 4.873743236638839, "Hypoxia": 4.639274883002148, "Immune reconstitution inflammatory syndrome": 9.737013362436642, "Immune thrombocytopenia": 2.686042786103918, "Intentional product use issue": 4.597188256118383, "Kidney fibrosis": 28.75917029524525, "Klebsiella bacteraemia": 56.73331181658339, "Large intestinal ulcer": 18.840331831147857, "Leukopenia": 11.182606028218691, "Liver disorder": 2.380944135646563, "Lung infiltration": 4.149060361502943, "Lung opacity": 8.68872095946977, "Lymphopenia": 3.5224167646458038, "Metabolic acidosis": 4.5232319866114725, "Multiple organ dysfunction syndrome": 11.93025485977306, "Myelosuppression": 8.681818500258082, "Nephropathy toxic": 17.35222385259939, "Nephrotic syndrome": 3.5443542776729555, "Neutropenia": 7.344294582704475, "Neutrophil Pelger-Huet anomaly present": 559.0386598035703, "Neutrophil count decreased": 3.433080153205167, "Off label use": 4.540702502524502, "Oliguria": 6.232025790696159, "Oral candidiasis": 5.375922212651754, "Oxygen saturation decreased": 2.166510407252186, "Pancytopenia": 15.183086190392933, "Pathogen resistance": 80.30511535194721, "Platelet count decreased": 2.7301707796880685, "Pneumocystis jirovecii pneumonia": 17.951250688834016, "Pneumonia bacterial": 5.285561322354974, "Pneumonia cytomegaloviral": 96.60966432325596, "Pneumonia fungal": 19.1127906397976, "Pneumonia lipoid": 261.0318101212616, "Pneumonia necrotising": 138.39174146074512, "Post transplant lymphoproliferative disorder": 27.977122528355924, "Product use in unapproved indication": 8.146721008049399, "Product use issue": 12.993841760372671, "Pseudomonas infection": 12.41252544005707, "Pulmonary hypertension": 2.3506556572309822, "Renal disorder": 2.98736524001437, "Renal failure": 2.20535036530226, "Renal impairment": 3.130888841537896, "Respiratory failure": 8.32610468249326, "Retinal degeneration": 36.80243120887074, "Retinal detachment": 15.433064259091855, "Retinitis": 56.1019253052003, "Sepsis": 4.403691767137607, "Septic shock": 7.811146700237906, "Shock": 4.025557232934711, "Staphylococcal infection": 3.48373986014909, "Systemic mycosis": 27.389445312530945, "Tachypnoea": 3.4069424331740854, "Thrombocytopenia": 7.689512110929728, "Thrombotic microangiopathy": 57.91471253342652, "Transplant dysfunction": 32.831780158127145, "Transplant rejection": 52.58484420039505, "Tubulointerstitial nephritis": 3.3693175426411206, "Viral load increased": 15.384479018341914, "Viral mutation identified": 35.3663445773665, "White blood cell count decreased": 4.441414615500608}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/5.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/5.json
index 34259b856ef..29a971d501f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/5.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/5.json
@@ -1 +1 @@
-{"Disease progression ": 102.944575958747}
\ No newline at end of file
+{"Abdominal discomfort": 6.659750684260724, "Abdominal pain upper": 3.7657906257391063, "Adjustment disorder with depressed mood": 61.30277575283727, "Adverse drug reaction": 2.347908264423284, "Alanine aminotransferase abnormal": 14.15957057368352, "Alopecia": 6.171295376896089, "Amnesia": 5.917278702494962, "Anal abscess": 3.5056966125328723, "Anti-cyclic citrullinated peptide antibody": 64.23401385262568, "Anti-cyclic citrullinated peptide antibody positive": 28.092508313799986, "Antibody test positive": 6.022164447106668, "Arthritis": 5.742169223621758, "Arthropathy": 14.991597381683468, "Asthma": 2.469495432065034, "Autoimmune disorder": 23.446222938073245, "Back injury": 25.35943514537494, "Basal cell carcinoma": 5.948055788320435, "Blepharospasm": 22.64347244750191, "Blister": 13.388410247714932, "Blood cholesterol": 12.160286065646591, "Blood cholesterol increased": 15.94880599594087, "Blood magnesium increased": 15.274339002351184, "Blood parathyroid hormone decreased": 21.408313323844627, "Body height below normal": 23.43303418319124, "Body temperature": 2.253260601374896, "Bone density increased": 20.20258202607362, "Bone erosion": 57.39440041919529, "Breast cancer stage I": 22.904182607066375, "Breast cancer stage II": 39.70986709121448, "Breast cancer stage III": 88.52794108854617, "Bunion operation": 16.787359344727705, "Bursitis": 30.314246862932205, "C-reactive protein": 17.56228449331537, "C-reactive protein abnormal": 29.577755591447133, "C-reactive protein increased": 10.921975440780797, "Colitis ulcerative": 3.727294240779463, "Condition aggravated": 2.790533834883867, "Confusional state": 4.397992178550276, "Contraindicated product administered": 17.15669557897606, "Contusion": 5.203083807785207, "Crohn's disease": 2.700149922809108, "Cyst": 2.964061660613872, "Deafness neurosensory": 3.364908280055548, "Deep vein thrombosis postoperative": 35.628808069944526, "Deformity": 8.230712323403948, "Delirium": 3.726424469169743, "Depression": 2.260664002139402, "Disability": 11.792513734963494, "Discomfort": 5.388689232694495, "Dislocation of vertebra": 56.28169291299853, "Drug hypersensitivity": 6.3726546320373885, "Drug ineffective": 2.13721053453374, "Drug intolerance": 7.467424440104997, "Drug specific antibody": 3.0535344804056086, "Drug tolerance": 5.7123329959021385, "Drug tolerance decreased": 10.424361328446915, "Drug-induced liver injury": 2.1118725701995067, "Dry mouth": 4.107443439775451, "Duodenal ulcer perforation": 28.05787125401948, "Ear infection": 4.466869729438858, "Ear pain": 5.721388987934711, "Enthesopathy": 18.749146120960493, "Epigastric discomfort": 4.410548357968583, "Epilepsy": 4.123184214704286, "Epstein-Barr viraemia": 4.781006377427552, "Exostosis": 20.161274679174117, "Facet joint syndrome": 50.98486852091079, "Fear of injection": 12.048885045617668, "Fibromyalgia": 13.867897090605986, "Finger deformity": 4.598575359437049, "Folliculitis": 37.44384211657482, "Foot deformity": 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3.10161202885721, "Infusion related reaction": 8.088783008785661, "Infusion site reaction": 142.59488943461523, "Injury": 5.995942188969836, "Intentional product use issue": 6.017868286319677, "Irritable bowel syndrome": 28.471055383750624, "Joint destruction": 23.2061020357899, "Joint dislocation": 5.580822404097319, "Joint effusion": 4.445238767926507, "Joint injury": 2.6461823404171314, "Joint range of motion decreased": 16.987291846741233, "Joint stiffness": 3.57642791335034, "Joint swelling": 10.142075487750692, "Juvenile idiopathic arthritis": 12.69075821063018, "Keratitis": 3.639916825124701, "Knee arthroplasty": 9.608013754360067, "Lip dry": 35.081534918210686, "Live birth": 20.481010563554022, "Liver function test increased": 7.510072940923513, "Liver injury": 6.234426444766801, "Lower respiratory tract infection": 17.766568993545725, "Lung disorder": 3.8649957690811534, "Lupus vulgaris": 7.416590058765951, "Lupus-like syndrome": 2.5302788497561126, "Maternal exposure during pregnancy": 4.0269430278235046, "Mean cell haemoglobin decreased": 12.67426175639904, "Mean cell volume decreased": 15.17663317675065, "Mean platelet volume decreased": 33.43629807720985, "Medication error": 2.5690288933952465, "Mobility decreased": 4.911186425367307, "Monocyte count increased": 6.664675665738876, "Muscle injury": 55.342635451091255, "Muscle spasticity": 14.681150299009458, "Musculoskeletal deformity": 94.3016459929373, "Musculoskeletal pain": 8.040490428855728, "Musculoskeletal stiffness": 2.4505928340228724, "Nail disorder": 32.031197120741275, "Nasopharyngitis": 5.975373607677288, "Night sweats": 7.685939104433996, "Obesity": 11.23174663510611, "Onychomadesis": 29.40170431181298, "Osteoarthritis": 6.137642016500419, "Panniculitis": 7.336970830511453, "Pemphigus": 10.648022528173502, "Pericarditis": 3.060557010682567, "Peripheral swelling": 4.306006403966413, "Peripheral venous disease": 6.978953287063144, "Physical disability": 2.920296795161282, "Pleural fibrosis": 22.84060209695842, "Pleural thickening": 11.481333752274583, "Presbyacusis": 33.715307282371825, "Prescribed underdose": 2.222214556680877, "Product use issue": 2.5339004086567067, "Psoriatic arthropathy": 3.381154154126727, "Pulmonary fibrosis": 2.4149388750349767, "Red blood cell sedimentation rate": 30.0403683165922, "Red blood cell sedimentation rate abnormal": 11.229667801459438, "Red blood cell sedimentation rate increased": 5.467282779962984, "Red cell distribution width decreased": 69.3679888439009, "Red cell distribution width increased": 2.506582333461751, "Respiratory disorder": 5.853704660088353, "Respiratory tract congestion": 2.87375404461545, "Retinitis": 7.381688407250523, "Rheumatic fever": 13.65517488085094, "Rheumatoid arthritis": 6.101438062329308, "Rheumatoid factor positive": 13.035815573804806, "Rheumatoid lung": 15.615580203277398, "Rheumatoid nodule": 12.427355017890552, "Sciatica": 2.981251192311463, "Seronegative arthritis": 7.113872176615304, "Sinusitis": 12.634943456683253, "Sleep disorder due to general medical condition, insomnia type": 55.88231022858083, "Spinal fusion surgery": 4.481770542372643, "Spondylitis": 3.816607061082314, "Stomatitis": 6.807118034592655, "Swelling": 4.962751571871745, "Swollen joint count increased": 19.682559956983248, "Synovitis": 10.2532646246841, "Systemic lupus erythematosus": 6.674290346891963, "Systemic lupus erythematosus rash": 8.64290427068908, "Tenosynovitis": 2.9922363766505007, "Therapeutic product effect decreased": 13.2840236306881, "Treatment failure": 4.0608825263063775, "Type 2 diabetes mellitus": 2.12894227095542, "Vascular access complication": 18.84427211959225, "Viral upper respiratory tract infection": 3.7438171623697754, "Walking aid user": 6.150198795536324, "Weight increased": 3.2206469477832638, "White blood cell count abnormal": 5.24049227373138, "Wound": 6.751327164317323, "Wound infection": 8.118497490867515, "Wrist deformity": 15.488297320208538, "X-ray abnormal": 10.689411445373567}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/50.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/50.json
index 56b854e4396..21c614a1c17 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/50.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/50.json
@@ -1 +1 @@
-{"Abdominal pain ": 6.253153425659666, "Anaemia ": 7.573133338189613, "Chronic sinusitis ": 187.57056845762975, "Colitis ": 52.142493528516816, "Colitis ulcerative ": 54.707103603432806, "Constipation ": 12.740764314155877, "Drug ineffective ": 2.548889891292984, "Erythema ": 6.745671411025831, "Female genital tract fistula ": 297.0486247413064, "Frequent bowel movements ": 106.10161277887882, "Haematochezia ": 34.126519537307274, "Macular degeneration ": 103.1497414299534, "Malaise ": 2.201146362300357, "Off label use ": 3.880435553525409, "Oral candidiasis ": 108.67658809148702, "Pain ": 2.930915342815897, "Paraesthesia oral ": 48.55558979401639, "Proctitis ": 260.373752025888, "Radiculopathy ": 226.210064349624, "Rectal haemorrhage ": 39.60665694701842, "Vaginal discharge ": 164.720966623618, "Vaginal flatulence ": 351.0289539109318, "Weight decreased ": 9.531297239540326}
\ No newline at end of file
+{"Respiratory failure": 27.315720864440745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/500.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/500.json
index 0ec6dbff7df..725ccf3b57c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/500.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/500.json
@@ -1 +1 @@
-{"Abnormal dreams ": 6.497984733688627, "Abnormal weight gain ": 42.45953955944619, "Abortion induced ": 15.898322827889846, "Abortion spontaneous ": 4.043792838386082, "Acne ": 3.6600306136655134, "Blood HIV RNA increased ": 247.8087451022996, "Blood cholesterol increased ": 2.805383525788392, "Blood creatinine increased ": 5.129126880869724, "Blood triglycerides increased ": 7.239790169897224, "CD4 lymphocytes decreased ": 119.993372288535, "Cushing's syndrome ": 58.80559164885881, "Drug ineffective ": 2.211442552066996, "Drug interaction ": 8.065500855669791, "Drug resistance ": 19.78828288861536, "Electrocardiogram QT prolonged ": 2.024462664843837, "Erectile dysfunction ": 3.774034089626056, "Fanconi syndrome acquired ": 17.858175899779543, "Flatulence ": 3.347664316183144, "Gastrointestinal tube insertion ": 52.6857427621192, "Gastrostomy ": 58.36946654505461, "Genotype drug resistance test positive ": 109.00034409569749, "Glomerular filtration rate decreased ": 11.564132450969906, "Hypercholesterolaemia ": 11.364104759277613, "Hypophosphataemia ": 15.986854278908874, "Immune reconstitution inflammatory syndrome ": 25.972807278919174, "Lactic acidosis ": 2.432816034194554, "Maternal exposure during pregnancy ": 5.323618502408802, "Mental disorder ": 2.5728594074446365, "Nightmare ": 4.244136125566038, "Osteonecrosis ": 3.2009706595492253, "Osteoporosis ": 3.61735310944852, "Renal impairment ": 3.497231902671679, "Rhabdomyolysis ": 2.3981420925930146, "Treatment failure ": 4.39197973060792, "Treatment noncompliance ": 14.371531536341797, "Tuberculosis ": 7.518712043146201, "Viral load increased ": 124.54115527873388, "Virologic failure ": 48.04037800029135, "Weight increased ": 14.713144842688632, "Wrong technique in product usage process ": 2.0275586377277617}
\ No newline at end of file
+{"Ovarian hyperstimulation syndrome": 2008.8510980136048}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/501.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/501.json
index a800f32b74b..111ca01555a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/501.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/501.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 3.046611549873918, "Balance disorder ": 3.359439326763692, "Blood pressure decreased ": 2.119553690057187, "Central nervous system lesion ": 101.42805789536058, "Gait disturbance ": 3.163418741868322, "Gamma-glutamyltransferase increased ": 5.714944132661755, "Hepatocellular injury ": 17.187168117464328, "Lymphocyte count decreased ": 42.09043696906324, "Memory impairment ": 2.5974757118218323, "Mobility decreased ": 2.103802492704021, "Movement disorder ": 7.327885998189389, "Multiple sclerosis ": 15.36785179420972, "Multiple sclerosis relapse ": 50.62157833187744, "Muscle spasms ": 2.3840007662375875, "Muscular weakness ": 2.4229811879196266, "Musculoskeletal stiffness ": 2.636150437711364, "Prescribed underdose ": 10.849328929140706, "Stress ": 9.27220948299212, "Urinary tract infection ": 3.4796650318437736, "Vision blurred ": 2.3574777980921424, "Visual impairment ": 2.2612639621503563, "Weight increased ": 2.8041880415230245, "White blood cell count decreased ": 3.035252966684209}
\ No newline at end of file
+{"Abdominal pain": 2.184502074062689, "Abdominal pain lower": 3.4012786098137373, "Abnormal loss of weight": 2.2635609413244744, "Abortion induced": 11.804580931956572, "Abortion missed": 3.5810030082947564, "Abortion spontaneous": 4.204782983496123, "Acne": 4.271315468787484, "Acute disseminated encephalomyelitis": 22.16354484870209, "Acute sinusitis": 5.391267294317867, "Adenocarcinoma of the cervix": 54.1932788499651, "Adverse event": 3.220604709138017, "Adverse event following immunisation": 25.915461537995174, "Alcohol intolerance": 3.997143694867675, "Allergy to animal": 5.06044881761342, "Allergy to vaccine": 11.178778725263795, "Allodynia": 8.299626783196151, "Alopecia areata": 2.779844396609774, "Amniotic cavity infection": 4.142644689710695, "Amplified musculoskeletal pain syndrome": 145.51225347647076, "Amyotrophic lateral sclerosis": 2.941585496084374, "Angiopathy": 3.550093183006948, "Anogenital warts": 72.65606894254631, "Anorexia nervosa": 10.72942061592284, "Anti-thyroid antibody": 18.15384972895468, "Anti-thyroid antibody positive": 4.171913179417255, "Antibody test negative": 4.818781612933058, "Antinuclear antibody positive": 3.7864937317592338, "Antiphospholipid syndrome": 6.271562033230672, "Anxiety disorder": 3.542877015599678, "Anxiety disorder due to a general medical condition": 52.9345240341982, "Appendicectomy": 6.2699308076641325, "Areflexia": 4.340270932646788, "Arnold-Chiari malformation": 4.486955127273264, "Arrested labour": 17.059728529030046, "Arthritis reactive": 4.487941083354287, "Asthma exercise induced": 30.20561878252772, "Astigmatism": 2.9041705346459343, "Ataxia": 2.372710911892667, "Atonic seizures": 3.1818444584995884, "Attention deficit hyperactivity disorder": 4.851267571153799, "Autoimmune disorder": 9.804258908793251, "Autoimmune encephalopathy": 27.682357980940907, "Autoimmune neuropathy": 15.68810972734583, "Autoimmune thyroiditis": 6.604799007513588, "Autonomic nervous system imbalance": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/502.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/502.json
index 81116a5bcd6..f449c2eca67 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/502.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/502.json
@@ -1 +1 @@
-{"Off label use ": 5.159578181043231, "Product use issue ": 19.95552235996222}
\ No newline at end of file
+{"Asthenia": 3.022950398981235, "Blood pressure increased": 2.72969538891131, "Constipation": 4.832476487321132, "Disease progression": 4.597574737685297, "Haemoglobin decreased": 5.329737906351069, "Hypertension": 2.4759800035756974, "Interstitial lung disease": 4.413154285043648, "Myelosuppression": 4.963177993943318, "Platelet count decreased": 4.198244499545837, "Pneumonia": 2.210008769813186, "White blood cell count decreased": 8.64198337776074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/503.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/503.json
index 8be79d9f524..7f21e008181 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/503.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/503.json
@@ -1 +1 @@
-{"Decreased appetite ": 4.022146304723201, "Diarrhoea ": 7.461938157045687, "Eosinophil count increased ": 116.62312369149006, "Interstitial lung disease ": 9.816971239455752, "Malignant neoplasm progression ": 9.972907481194987, "Rash ": 4.417139581706117, "Vomiting ": 2.663433536452429}
\ No newline at end of file
+{"Agranulocytosis": 4.248517937858285, "Blood lactate dehydrogenase increased": 5.683274155706481, "Blood pressure decreased": 2.399377115575674, "Bronchospasm": 4.758965037954392, "Chronic lymphocytic leukaemia recurrent": 153.9177200122778, "Cytokine release syndrome": 7.439178634620165, "Cytopenia": 9.66726148813115, "Disease progression": 3.8285437968358393, "Febrile neutropenia": 3.821791946146434, "Flushing": 3.347854905861323, "Follicular lymphoma": 82.14643210998236, "Hepatic cytolysis": 8.076937563672756, "Hepatitis": 2.020561315200754, "Hyperhidrosis": 2.236148330981218, "Hypertransaminasaemia": 5.860827136769324, "Hypotension": 4.517817646390943, "Hypoxia": 2.6807289258052616, "Ill-defined disorder": 2.460101203810525, "Infection": 2.8107207937120644, "Infusion related reaction": 46.704607631476414, "Intentional product use issue": 6.243268441841447, "Leukopenia": 6.630361595865043, "Liver function test abnormal": 2.197509857588608, "Lymphocyte count decreased": 11.794093682792798, "Lymphopenia": 10.1813265001177, "Neutropenia": 15.80684614072697, "Neutropenic sepsis": 16.682693453617606, "Off label use": 2.3623913548268187, "Oxygen saturation decreased": 4.756426044784401, "Pancytopenia": 3.1488774714946244, "Platelet count decreased": 4.223588009009061, "Progressive multifocal leukoencephalopathy": 61.29121853312946, "Respiratory distress": 2.094093299040895, "Respiratory failure": 2.447808065294266, "Respiratory tract infection": 10.827224774667783, "Sepsis": 3.75867993528057, "Septic shock": 3.751810518334477, "Splenomegaly": 5.186336641566154, "Thrombocytopenia": 10.33048555327305, "Transaminases increased": 5.214338362687133, "Tumour lysis syndrome": 111.77361695970691, "White blood cell count decreased": 3.625977881056468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/504.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/504.json
index 2fcba656d24..0fb601d4f25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/504.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/504.json
@@ -1 +1 @@
-{"Hepatocellular carcinoma ": 577.3223763570121}
\ No newline at end of file
+{"Acquired gene mutation": 1332.9235146927251, "Alanine aminotransferase increased": 2.94912070123708, "Aspartate aminotransferase increased": 2.2138362594757086, "Dermatitis acneiform": 51.80496949539893, "Diarrhoea": 2.5027435934227897, "Disease progression": 8.704496992032258, "Drug interaction": 2.170150005911798, "Drug resistance": 149.64231670061238, "Drug-induced liver injury": 6.501717923761754, "EGFR gene mutation": 3703.5645799823487, "Gene mutation": 76.17624291310764, "Hepatic function abnormal": 6.852372897748949, "Hepatotoxicity": 12.271814291520244, "Interstitial lung disease": 15.91222092680261, "Left ventricular dysfunction": 13.46179432791123, "Liver function test abnormal": 5.501414530026557, "Liver injury": 5.327021095731904, "Lung adenocarcinoma": 47.32440281927434, "Lung adenocarcinoma stage IV": 369.3220082985871, "Malignant neoplasm progression": 51.87421790053863, "Malignant transformation": 2091.4869565741496, "Metastases to bone": 35.13422829398389, "Metastases to central nervous system": 137.6437376626633, "Metastases to liver": 24.86186010700512, "Metastases to lung": 36.13115434155291, "Metastases to lymph nodes": 20.77716717434163, "Metastases to meninges": 393.0899666966118, "Metastasis": 23.41666785477021, "Myelosuppression": 2.814276526251704, "Non-small cell lung cancer": 28.23458809957795, "Pancreatitis acute": 3.5635039625955947, "Paronychia": 87.68899063871469, "Pericardial effusion": 3.7159938383499753, "Pleural effusion": 7.308608313087951, "Pneumonitis": 4.128659506926195, "Pulmonary mass": 6.943093835059006, "Rash": 3.116385748900881, "Rash pruritic": 2.988448749588748, "Rash pustular": 14.735475412541208, "Respiratory failure": 2.752943612368452, "Skin toxicity": 48.78450310869522, "Small cell lung cancer": 241.04846799687147, "Transaminases increased": 4.383230245385356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/505.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/505.json
index 0b22c7e9f9b..48d52cb2e07 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/505.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/505.json
@@ -1 +1 @@
-{"Accidental exposure to product ": 9.795380822874098, "Accidental overdose ": 6.221685489167692, "Acute kidney injury ": 2.577669694090112, "Altered state of consciousness ": 8.079651360125947, "Angina pectoris ": 2.21251521654856, "Anuria ": 12.081899525524816, "Blood alkaline phosphatase increased ": 2.1133991457305017, "Blood glucose decreased ": 6.087563785479241, "Blood glucose increased ": 3.96832630937974, "Cardiac arrest ": 2.453516639566473, "Circulatory collapse ": 2.166189922860537, "Coma ": 3.787670881894487, "Completed suicide ": 10.453529395671554, "Confusional state ": 2.835950971867355, "Conjunctivitis ": 4.372939724984836, "Counterfeit product administered ": 134.63686688493428, "Depressed level of consciousness ": 2.483960358131197, "Diabetes mellitus ": 2.577830737863397, "Diabetes mellitus inadequate control ": 8.447044086679902, "Diabetic metabolic decompensation ": 35.260944383327974, "Drug interaction ": 7.104544659220222, "Drug-induced liver injury ": 6.102421042908908, "Dyspepsia ": 2.2505005264179623, "Glycosylated haemoglobin increased ": 10.995062700252134, "Hemiparesis ": 4.794773706938801, "Hemiplegia ": 7.03976088340772, "Hepatitis ": 2.4547530042717267, "Hepatitis cholestatic ": 5.460949687430225, "Hyperglycaemia ": 4.706674707957352, "Hyperosmolar state ": 292.1432991117906, "Hypoglycaemia ": 51.17085652926136, "Hypoglycaemic coma ": 39.63162497496122, "Hypoglycaemic encephalopathy ": 109.90323462233904, "Hypomagnesaemia ": 11.499718958336542, "Intentional overdose ": 4.961168312689323, "Ischaemic cardiomyopathy ": 19.06529631221713, "Ketoacidosis ": 6.751282271018541, "Lactic acidosis ": 8.31553636135406, "Liver injury ": 2.981297510437962, "Loss of consciousness ": 2.5160774022959425, "Magnetic resonance imaging head abnormal ": 61.25440741479058, "Medication error ": 5.299132169168445, "Metabolic acidosis ": 5.124426232136686, "Oedema peripheral ": 2.566651853169521, "Overdose ": 5.82406378973073, "Potentiating drug interaction ": 15.534782092063216, "Product administration error ": 2.712001718556157, "Prothrombin time prolonged ": 8.817379841070919, "Respiratory acidosis ": 22.66230604191093, "Respiratory arrest ": 2.537681922005944, "Speech disorder ": 2.7727315351549358, "Suicide attempt ": 3.2095868498185336, "Toxic epidermal necrolysis ": 4.464358534980282, "Toxicity to various agents ": 7.289764147767682, "Treatment noncompliance ": 3.5067249534129985, "Unresponsive to stimuli ": 9.77031366872226, "Vertigo ": 2.5014505983458872}
\ No newline at end of file
+{"Exposure during pregnancy": 10.110248300423528, "Hypotonia": 38.23211180675602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/506.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/506.json
index d7b967525ce..33d1b30c99b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/506.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/506.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 3.155830942503086, "Amylase increased ": 6.833184366588426, "Anaemia ": 2.0840723440929416, "Ascites ": 3.7386500859838, "Aspartate aminotransferase increased ": 3.002318861259404, "Blast crisis in myelogenous leukaemia ": 151.94204221717925, "Blood alkaline phosphatase increased ": 2.255657290512484, "Blood bilirubin increased ": 4.727285422385485, "Blood creatine phosphokinase increased ": 2.186224402457388, "Blood creatinine increased ": 2.113209105200056, "Blood lactate dehydrogenase increased ": 6.630800153905613, "Blood urea increased ": 2.895534618079424, "Cardiac failure ": 3.492946868742859, "Cholestasis ": 2.728410474128639, "Chronic myeloid leukaemia ": 71.92088625322938, "Cytogenetic analysis abnormal ": 121.67699341122147, "Cytopenia ": 5.404369366278683, "Disease progression ": 2.0473689667708865, "Disseminated intravascular coagulation ": 3.967847195584105, "Drug interaction ": 2.556150195732858, "Drug intolerance ": 3.5773576897477954, "Drug level increased ": 2.895876863807616, "Drug resistance ": 11.69634249410196, "Dry skin ": 2.430498185370144, "Dyspnoea exertional ": 2.1223782339139228, "Eyelid oedema ": 7.052587376183572, "Face oedema ": 4.190474902876286, "Fluid retention ": 4.104582543104602, "Gamma-glutamyltransferase increased ": 2.202234744166533, "Gastrointestinal stromal tumour ": 339.22883004376786, "Gene mutation identification test positive ": 112.40264336280148, "Generalised oedema ": 8.991406170302016, "Haematocrit decreased ": 3.902234984905897, "Haematotoxicity ": 7.928366869414983, "Haemoglobin decreased ": 2.85573832516597, "Hepatic cytolysis ": 2.734300830273523, "Hepatomegaly ": 6.477623546234107, "Interstitial lung disease ": 3.256985486366577, "Liver disorder ": 2.751413058219708, "Lymphocyte count increased ": 30.45990786871446, "Malignant neoplasm progression ": 16.61708138935664, "Metastases to bone ": 3.703569971895906, "Metastases to liver ": 21.08590054413992, "Metastases to peritoneum ": 34.11910597613456, "Metastasis ": 10.76041380931471, "Neoplasm progression ": 4.218123562435118, "Neoplasm recurrence ": 89.01957280268876, "Neutrophil count decreased ": 2.174003328057586, "Oedema ": 7.841440942489659, "Oedema peripheral ": 3.602497233283783, "Pancytopenia ": 5.522855685862163, "Pericardial effusion ": 2.972249723445658, "Periorbital oedema ": 10.545992373431394, "Platelet count decreased ": 4.2490119531061685, "Platelet count increased ": 4.857422139270834, "Pleural effusion ": 9.489629644111986, "Pulmonary fibrosis ": 2.498061624517764, "Pulmonary hypertension ": 3.956278344060807, "Red blood cell count decreased ": 2.623605299030118, "Second primary malignancy ": 22.180719621427308, "Skin exfoliation ": 3.3793741361913217, "Splenomegaly ": 4.059251768089615, "Squamous cell carcinoma ": 7.430656658134777, "Subdural haematoma ": 4.243015128614345, "Therapeutic response decreased ": 5.865927545672381, "Thrombocytopenia ": 2.0423116207111267, "White blood cell count decreased ": 3.2449237429848106, "White blood cell count increased ": 7.808149539327949}
\ No newline at end of file
+{"Abnormal dreams": 6.497984733688627, "Abnormal weight gain": 42.45953955944619, "Abortion induced": 15.898322827889846, "Abortion spontaneous": 4.043792838386082, "Acne": 3.6600306136655134, "Blood HIV RNA increased": 247.8087451022996, "Blood cholesterol increased": 2.805383525788392, "Blood creatinine increased": 5.129126880869724, "Blood triglycerides increased": 7.239790169897224, "CD4 lymphocytes decreased": 119.993372288535, "Cushing's syndrome": 58.80559164885881, "Drug ineffective": 2.211426199073466, "Drug interaction": 8.065500855669791, "Drug resistance": 19.78828288861536, "Electrocardiogram QT prolonged": 2.024462664843837, "Erectile dysfunction": 3.774034089626056, "Fanconi syndrome acquired": 17.858175899779543, "Flatulence": 3.347392160246422, "Gastrointestinal tube insertion": 52.6857427621192, "Gastrostomy": 58.36946654505461, "Genotype drug resistance test positive": 109.00034409569749, "Glomerular filtration rate decreased": 11.564132450969906, "Hypercholesterolaemia": 11.364104759277613, "Hypophosphataemia": 15.986854278908874, "Immune reconstitution inflammatory syndrome": 25.972807278919174, "Lactic acidosis": 2.432816034194554, "Maternal exposure during pregnancy": 5.323618502408802, "Mental disorder": 2.5728594074446365, "Nightmare": 4.244136125566038, "Osteonecrosis": 3.2009706595492253, "Osteoporosis": 3.61735310944852, "Renal impairment": 3.497231902671679, "Rhabdomyolysis": 2.3981420925930146, "Treatment failure": 4.39197973060792, "Treatment noncompliance": 14.371531536341797, "Tuberculosis": 7.518712043146201, "Viral load increased": 124.54115527873388, "Virologic failure": 48.04037800029135, "Weight increased": 14.713144842688632, "Wrong technique in product usage process": 2.0275586377277617}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/507.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/507.json
index c7647e8c367..c1a224c4d3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/507.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/507.json
@@ -1 +1 @@
-{"Cytokine release syndrome ": 625.5810417020712}
\ No newline at end of file
+{"Alanine aminotransferase increased": 3.046611549873918, "Balance disorder": 3.359439326763692, "Blood pressure decreased": 2.1194849036203207, "Central nervous system lesion": 101.42805789536058, "Gait disturbance": 3.16336138295608, "Gamma-glutamyltransferase increased": 5.714944132661755, "Hepatocellular injury": 17.182159324512153, "Lymphocyte count decreased": 42.09043696906324, "Memory impairment": 2.5974757118218323, "Mobility decreased": 2.103802492704021, "Movement disorder": 7.327885998189389, "Multiple sclerosis": 15.36785179420972, "Multiple sclerosis relapse": 50.62157833187744, "Muscle spasms": 2.3840007662375875, "Muscular weakness": 2.4229811879196266, "Musculoskeletal stiffness": 2.636150437711364, "Prescribed underdose": 10.849328929140706, "Stress": 9.27220948299212, "Urinary tract infection": 3.4796650318437736, "Vision blurred": 2.3574777980921424, "Visual impairment": 2.2612639621503563, "Weight increased": 2.8041880415230245, "White blood cell count decreased": 3.035252966684209}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/508.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/508.json
index 4e18c3301b7..9bda8d10739 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/508.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/508.json
@@ -1 +1 @@
-{"Accidental overdose ": 5.725508664208805, "Acute kidney injury ": 2.315185461083165, "Altered state of consciousness ": 3.375257157275059, "Anaphylactic shock ": 2.314713020934067, "Blood glucose abnormal ": 6.807152851030573, "Blood glucose decreased ": 48.71665973824195, "Blood glucose increased ": 6.739463185007669, "Blood pressure decreased ": 3.3064462273079416, "Bradycardia ": 11.913955633636368, "Cardiac arrest ": 22.185338824506704, "Cardiogenic shock ": 33.14749217031573, "Circulatory collapse ": 5.373584282813225, "Coma ": 3.0211698752762173, "Coma scale abnormal ": 108.83144302429626, "Compartment syndrome ": 194.11095942823283, "Completed suicide ": 4.21177125709921, "Diabetic ketoacidosis ": 4.34660284657334, "Drug ineffective ": 5.02840652398542, "Drug screen positive ": 55.20627207166592, "Expired product administered ": 29.898897788173056, "General physical health deterioration ": 2.9611934369234327, "Haemodynamic instability ": 25.63312861873641, "Hyperglycaemia ": 3.664733570106926, "Hyperkalaemia ": 6.979467708295187, "Hypoglycaemia ": 7.743640885452296, "Hypoglycaemic coma ": 11.010667654901065, "Hypoglycaemic seizure ": 34.40708570720253, "Hypoglycaemic unconsciousness ": 29.10304710028644, "Hypotension ": 4.66301321708725, "Hypoxic-ischaemic encephalopathy ": 87.4524883122731, "Ileus ": 40.15298729404237, "Incorrect dose administered ": 6.476510556395466, "Intentional overdose ": 7.143546894706867, "Lactic acidosis ": 18.29339663212248, "Loss of consciousness ": 4.92958606716744, "Mental status changes ": 16.45119628948413, "Metabolic acidosis ": 5.638466002694288, "Overdose ": 4.220962392169906, "Product dose omission issue ": 2.060998830785458, "Pulmonary oedema ": 3.5913178479123147, "Pulse absent ": 88.60645199749415, "Pulseless electrical activity ": 64.35217573762536, "Pupil fixed ": 82.10159750584485, "Respiratory depression ": 17.646401564870867, "Rhabdomyolysis ": 7.381719612016032, "Seizure ": 3.52075660027208, "Shock ": 16.698931492150127, "Therapy non-responder ": 4.22074370129061, "Toxicity to various agents ": 4.284395064895399, "Underdose ": 10.913071924340004, "Unresponsive to stimuli ": 5.312935100752528, "Vasoplegia syndrome ": 430.11637551698135, "Ventricular tachycardia ": 9.349221107426205, "Wrong technique in product usage process ": 3.338051756732825}
\ No newline at end of file
+{"Off label use": 5.159374977925141, "Product use issue": 19.95552235996222}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/509.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/509.json
index 9f5aac164f0..b7c8159796f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/509.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/509.json
@@ -1 +1 @@
-{"Drug ineffective ": 5.558796623389982, "Product use in unapproved indication ": 12.8056308144212}
\ No newline at end of file
+{"Decreased appetite": 4.022107292955628, "Diarrhoea": 7.461875879343185, "Eosinophil count increased": 116.62312369149006, "Interstitial lung disease": 9.816971239455752, "Malignant neoplasm progression": 9.972907481194987, "Rash": 4.417078906300239, "Vomiting": 2.663397608755122}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/51.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/51.json
index 241de36ee19..db8b81d467a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/51.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/51.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 2.617058852760312, "Acute generalised exanthematous pustulosis ": 2.690328480427259, "Acute kidney injury ": 3.555821019126201, "Acute pulmonary oedema ": 2.6168619496727743, "Acute respiratory failure ": 2.7962291805598927, "Alanine aminotransferase increased ": 2.091530432423037, "Anaemia ": 6.453276168811002, "Aspartate aminotransferase increased ": 2.2557852986376656, "Bicytopenia ": 8.5834952554688, "Blood creatinine increased ": 2.987016799152558, "Blood magnesium decreased ": 3.086813710840838, "Bone marrow failure ": 20.46912666549953, "C-reactive protein increased ": 2.333829419537141, "Cellulitis ": 2.0837567409464275, "Cerebral infarction ": 2.3467513619486966, "Cholestasis ": 2.7498367473777408, "Colitis ": 5.33372639244486, "Colitis ischaemic ": 3.015439272301613, "Congenital aplasia ": 34.66324134269079, "Conjunctivitis ": 4.653762108630027, "Creatinine renal clearance decreased ": 10.038157603883564, "Cytopenia ": 2.4674156962593914, "Death ": 2.133419272886312, "Decreased appetite ": 2.4469540187018746, "Dehydration ": 2.515387220258124, "Dermatitis ": 3.381060798117484, "Dermatitis bullous ": 3.992593480382662, "Dermatitis exfoliative generalised ": 2.545215994788846, "Dermo-hypodermitis ": 41.13463772213367, "Disease progression ": 2.222518193787234, "Disseminated intravascular coagulation ": 4.687109409484428, "Drug eruption ": 2.247294419904118, "Enteritis ": 6.178735748091023, "Enterocolitis ": 6.342254726887617, "Erysipelas ": 9.190805937962253, "Eyelid oedema ": 2.545970090401545, "Febrile bone marrow aplasia ": 45.737569991035, "Febrile neutropenia ": 11.926965603202683, "Gastrointestinal necrosis ": 7.540149650996057, "Gastrointestinal perforation ": 4.130067607171318, "Gastrointestinal toxicity ": 4.251609047365809, "General physical health deterioration ": 3.3219538157415496, "Generalised oedema ": 3.466945943486511, "Granulocytopenia ": 2.359095986139691, "Haematocrit decreased ": 2.4102747656145813, "Haematotoxicity ": 18.18047000409302, "Haemoglobin decreased ": 2.6613181790944767, "Haemolytic anaemia ": 2.222335508831179, "Haemoptysis ": 4.193107464974718, "Hepatic cytolysis ": 6.05624656232113, "Hepatocellular injury ": 4.680294300918038, "Hiccups ": 5.019894154420486, "Hospice care ": 17.62796954419729, "Hypertransaminasaemia ": 6.236898858634018, "Hypoalbuminaemia ": 3.3909226247658046, "Hypocalcaemia ": 2.173852545930351, "Hypomagnesaemia ": 2.4718487309531003, "Hypophagia ": 2.0094844354584547, "Ileus ": 2.156734372783618, "Immune-mediated enterocolitis ": 3.896940114643466, "Immune-mediated hepatic disorder ": 11.472469817689513, "Immune-mediated hepatitis ": 5.003016610445751, "Immune-mediated lung disease ": 5.836701153509392, "Infectious pleural effusion ": 9.738364710619626, "Interstitial lung disease ": 15.30992891974501, "Intestinal perforation ": 4.906375220694746, "Ischaemic stroke ": 2.3104260269948287, "Lacrimation increased ": 3.733165771183845, "Large intestine perforation ": 3.800956215802575, "Left ventricular dysfunction ": 2.708297761606201, "Leukoencephalopathy ": 5.458262979281818, "Leukopenia ": 5.364298037301018, "Lichenoid keratosis ": 7.922876019064592, "Liver disorder ": 2.3133165310214348, "Lung adenocarcinoma ": 7.515945786741905, "Lung disorder ": 4.001933990182212, "Lung infiltration ": 2.6404197018067697, "Lymphocyte count decreased ": 2.50187372835504, "Lymphoedema ": 2.48076188490676, "Malignant neoplasm progression ": 22.685301763025528, "Malignant pleural effusion ": 11.283119446394767, "Metastases to central nervous system ": 2.985369263592658, "Metastases to meninges ": 9.324240708755696, "Mucosal inflammation ": 20.667109300032763, "Myelosuppression ": 8.335613859382482, "Myositis ": 2.1465364922288632, "Neoplasm progression ": 10.840530994796836, "Nephritis ": 9.359551566284056, "Nephrogenic diabetes insipidus ": 5.255493209810065, "Nephropathy toxic ": 8.349366848945547, "Nephrotic syndrome ": 2.9074035701178365, "Neutropenia ": 8.532196322030602, "Neutropenic sepsis ": 13.71526175504257, "Neutrophil count decreased ": 6.9106502276361645, "Non-small cell lung cancer ": 7.367040542798005, "Oedema peripheral ": 2.9470339843375943, "Oesophageal candidiasis ": 4.050268647332098, "Oesophagitis ": 4.193420773445412, "Off label use ": 3.983355233904703, "Oral candidiasis ": 2.75204136774328, "Organising pneumonia ": 6.0488465658707575, "Osteonecrosis of jaw ": 3.544968527356245, "Ototoxicity ": 7.685290052827204, "Pancytopenia ": 19.1483356397338, "Panniculitis ": 3.682938896503301, "Performance status decreased ": 3.5968138033072456, "Pericardial effusion ": 2.409438826500479, "Periorbital oedema ": 2.177206815011948, "Peripheral ischaemia ": 3.4355198825332045, "Peripheral sensory neuropathy ": 2.454926443280172, "Peritonitis ": 3.129826647901603, "Platelet count decreased ": 5.816457706133234, "Pleural effusion ": 5.273227639183809, "Pneumonia bacterial ": 2.7835395416865327, "Pneumonitis ": 16.13262891593914, "Pneumothorax ": 3.910957483134511, "Pulmonary fibrosis ": 2.1651331781184164, "Pulmonary toxicity ": 4.386769903852649, "Purpura ": 2.9734339382927057, "Radiation pneumonitis ": 26.29113537833904, "Rash maculo-papular ": 3.498597603812271, "Recall phenomenon ": 104.6420389196962, "Renal disorder ": 2.302294347555595, "Renal failure ": 3.8701610265979496, "Renal impairment ": 3.1511603449487717, "Renal tubular necrosis ": 4.194583772143596, "Respiratory failure ": 2.773193481391213, "Sepsis ": 3.4931073339188154, "Septic shock ": 6.783709797899157, "Skin hyperpigmentation ": 6.506928888966977, "Skin toxicity ": 8.063454286184985, "Small intestinal perforation ": 13.07884455767921, "Staphylococcal sepsis ": 4.528023227796149, "Stomatitis ": 3.789363909776583, "Therapy partial responder ": 5.731171086318192, "Thrombocytopenia ": 8.328954663643799, "Thrombophlebitis migrans ": 30.041564853641983, "Thrombotic thrombocytopenic purpura ": 2.457834580901952, "Toxic epidermal necrolysis ": 2.695801025604946, "Toxic skin eruption ": 5.678609767375122, "Transaminases increased ": 3.0260800569235307, "Tubulointerstitial nephritis ": 8.117682543728291, "White blood cell count decreased ": 3.7213138808959054}
\ No newline at end of file
+{"Abdominal pain": 6.253153425659666, "Anaemia": 7.573133338189613, "Chronic sinusitis": 187.57056845762975, "Colitis": 52.142493528516816, "Colitis ulcerative": 54.707103603432806, "Constipation": 12.740764314155877, "Drug ineffective": 2.5488710494667037, "Erythema": 6.74560542679206, "Female genital tract fistula": 297.0486247413064, "Frequent bowel movements": 106.10161277887882, "Haematochezia": 34.12314227259775, "Macular degeneration": 103.1497414299534, "Malaise": 2.2011182597102232, "Off label use": 3.880282713907063, "Oral candidiasis": 108.67658809148702, "Pain": 2.9308904297651264, "Paraesthesia oral": 48.55558979401639, "Proctitis": 260.373752025888, "Radiculopathy": 226.210064349624, "Rectal haemorrhage": 39.60665694701842, "Vaginal discharge": 164.720966623618, "Vaginal flatulence": 351.0289539109318, "Weight decreased": 9.531297239540326}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/510.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/510.json
index 13a538015b5..6064bbc033f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/510.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/510.json
@@ -1 +1 @@
-{"Acute myocardial infarction ": 4.219261580589798, "Adjustment disorder ": 427.4883404179413, "Anxiety ": 4.414400461996598, "Arthritis ": 3.065367556652224, "Asthma ": 25.77078757650816, "Asthmatic crisis ": 14.8907051112214, "Blood cholesterol abnormal ": 34.820862400272105, "Blood immunoglobulin E increased ": 49.41222420313562, "Bronchial obstruction ": 46.3832179390269, "Bronchitis ": 2.813362071427512, "Chest discomfort ": 8.695522308024007, "Choking ": 12.690589165002294, "Chronic obstructive pulmonary disease ": 27.272757732136984, "Coronary artery disease ": 4.705417660094238, "Cough ": 6.647062857989785, "Crepitations ": 44.63352807829998, "Depressed mood ": 18.15735935340084, "Discomfort ": 13.775107205082568, "Drug intolerance ": 9.480612739064918, "Dyspnoea ": 4.943425113854635, "Emphysema ": 11.609128297957133, "Erythema nodosum ": 22.3821710176236, "Faeces discoloured ": 5.918613933203575, "Full blood count abnormal ": 66.17129266597702, "Gastrooesophageal reflux disease ": 18.322820597305565, "Glaucoma ": 12.489912142733584, "Haemoglobin decreased ": 5.51214585661806, "Hilar lymphadenopathy ": 109.3371858324765, "Hip fracture ": 4.21348263076589, "Hospitalisation ": 4.657433800374021, "Hypercholesterolaemia ": 80.32487096122237, "Hypersensitivity ": 2.0262044747623738, "Hyperthyroidism ": 3.854256490556567, "Hypogammaglobulinaemia ": 34.792259578287414, "Infection ": 6.229394483446552, "Laryngospasm ": 19.779587415293364, "Loss of personal independence in daily activities ": 28.87663885538977, "Lower respiratory tract infection ": 2.5610268125243865, "Nervousness ": 3.25780036988099, "Neutrophil count decreased ": 8.062605181958121, "Obesity ": 66.4218957243778, "Obstructive airways disorder ": 44.02344786435396, "Oxygen saturation decreased ": 4.032460186567593, "Productive cough ": 35.22558742791208, "Pulmonary mass ": 16.43957354278706, "Respiratory disorder ": 4.817130224566473, "Respiratory symptom ": 25.36879956410619, "Rhinitis allergic ": 175.31064955010729, "Sinus congestion ": 68.02362408683393, "Sleep disorder ": 2.3973991503472942, "Sleep disorder due to a general medical condition ": 134.64073509343035, "Sputum discoloured ": 81.47849535863254, "Therapeutic product effect incomplete ": 33.59464907354145, "Total lung capacity increased ": 632.3955860102072, "Upper-airway cough syndrome ": 75.31106485651519, "Wheezing ": 41.11811373712996}
\ No newline at end of file
+{"Hepatocellular carcinoma": 577.3223763570121}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/511.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/511.json
index e00551ee228..c141e0adc3d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/511.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/511.json
@@ -1 +1 @@
-{"Ectopic pregnancy ": 32649.084267910934}
\ No newline at end of file
+{"Accidental exposure to product": 9.795380822874098, "Accidental overdose": 6.221685489167692, "Acute kidney injury": 2.577669694090112, "Altered state of consciousness": 8.079651360125947, "Angina pectoris": 2.21251521654856, "Anuria": 12.081899525524816, "Blood alkaline phosphatase increased": 2.1133991457305017, "Blood glucose decreased": 6.087563785479241, "Blood glucose increased": 3.96832630937974, "Cardiac arrest": 2.453516639566473, "Circulatory collapse": 2.166189922860537, "Coma": 3.787670881894487, "Completed suicide": 10.453529395671554, "Confusional state": 2.835950971867355, "Conjunctivitis": 4.372939724984836, "Counterfeit product administered": 134.63686688493428, "Depressed level of consciousness": 2.483960358131197, "Diabetes mellitus": 2.577830737863397, "Diabetes mellitus inadequate control": 8.447044086679902, "Diabetic metabolic decompensation": 35.260944383327974, "Drug interaction": 7.104544659220222, "Drug-induced liver injury": 6.102048727677347, "Dyspepsia": 2.2505005264179623, "Glycosylated haemoglobin increased": 10.995062700252134, "Hemiparesis": 4.794169196949426, "Hemiplegia": 7.03976088340772, "Hepatitis": 2.4547530042717267, "Hepatitis cholestatic": 5.460949687430225, "Hyperglycaemia": 4.706674707957352, "Hyperosmolar state": 292.1432991117906, "Hypoglycaemia": 51.16910980326263, "Hypoglycaemic coma": 39.63162497496122, "Hypoglycaemic encephalopathy": 109.90323462233904, "Hypomagnesaemia": 11.499718958336542, "Intentional overdose": 4.961168312689323, "Ischaemic cardiomyopathy": 19.06529631221713, "Ketoacidosis": 6.751282271018541, "Lactic acidosis": 8.31553636135406, "Liver injury": 2.981297510437962, "Loss of consciousness": 2.515954219346846, "Magnetic resonance imaging head abnormal": 61.25440741479058, "Medication error": 5.298751643183773, "Metabolic acidosis": 5.124426232136686, "Oedema peripheral": 2.566588400020596, "Overdose": 5.82406378973073, "Potentiating drug interaction": 15.534782092063216, "Product administration error": 2.7117892714209537, "Prothrombin time prolonged": 8.817379841070919, "Respiratory acidosis": 22.66230604191093, "Respiratory arrest": 2.537681922005944, "Speech disorder": 2.7727315351549358, "Suicide attempt": 3.2095868498185336, "Toxic epidermal necrolysis": 4.464358534980282, "Toxicity to various agents": 7.289764147767682, "Treatment noncompliance": 3.5067249534129985, "Unresponsive to stimuli": 9.769237428900862, "Vertigo": 2.5014505983458872}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/512.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/512.json
index 7985e57cd53..9535ff301e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/512.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/512.json
@@ -1 +1 @@
-{"Arthritis ": 6.00074716211868, "Colitis ulcerative ": 8.373608110345094, "Drug ineffective ": 3.902474042084593, "Infection ": 5.081654607398911, "Lymphoproliferative disorder ": 171.54023905889187, "Pneumonia ": 2.6547594146589923, "Psoriasis ": 17.33678070325074, "Psoriatic arthropathy ": 8.370060998611207, "Rheumatoid arthritis ": 6.935613258051929, "Therapeutic product effect decreased ": 6.12036585884248}
\ No newline at end of file
+{"Alanine aminotransferase increased": 3.155830942503086, "Amylase increased": 6.833184366588426, "Anaemia": 2.0840723440929416, "Ascites": 3.7386500859838, "Aspartate aminotransferase increased": 3.002318861259404, "Blast crisis in myelogenous leukaemia": 151.94204221717925, "Blood alkaline phosphatase increased": 2.255657290512484, "Blood bilirubin increased": 4.727285422385485, "Blood creatine phosphokinase increased": 2.186224402457388, "Blood creatinine increased": 2.113209105200056, "Blood lactate dehydrogenase increased": 6.630800153905613, "Blood urea increased": 2.895534618079424, "Cardiac failure": 3.4926277853309724, "Cholestasis": 2.728410474128639, "Chronic myeloid leukaemia": 71.92088625322938, "Cytogenetic analysis abnormal": 121.67699341122147, "Cytopenia": 5.40006783835651, "Disease progression": 2.0473689667708865, "Disseminated intravascular coagulation": 3.967847195584105, "Drug interaction": 2.556150195732858, "Drug intolerance": 3.5773576897477954, "Drug level increased": 2.895876863807616, "Drug resistance": 11.69634249410196, "Dry skin": 2.430498185370144, "Dyspnoea exertional": 2.1223782339139228, "Eyelid oedema": 7.052587376183572, "Face oedema": 4.190474902876286, "Fluid retention": 4.104582543104602, "Gamma-glutamyltransferase increased": 2.202234744166533, "Gastrointestinal stromal tumour": 339.22883004376786, "Gene mutation identification test positive": 112.40264336280148, "Generalised oedema": 8.991406170302016, "Haematocrit decreased": 3.902234984905897, "Haematotoxicity": 7.928366869414983, "Haemoglobin decreased": 2.85573832516597, "Hepatic cytolysis": 2.734300830273523, "Hepatomegaly": 6.477623546234107, "Interstitial lung disease": 3.256985486366577, "Liver disorder": 2.751413058219708, "Lymphocyte count increased": 30.45990786871446, "Malignant neoplasm progression": 16.61708138935664, "Metastases to bone": 3.703569971895906, "Metastases to liver": 21.08590054413992, "Metastases to peritoneum": 34.11910597613456, "Metastasis": 10.76041380931471, "Neoplasm progression": 4.218123562435118, "Neoplasm recurrence": 89.01957280268876, "Neutrophil count decreased": 2.174003328057586, "Oedema": 7.841440942489659, "Oedema peripheral": 3.6024081290752563, "Pancytopenia": 5.522855685862163, "Pericardial effusion": 2.972249723445658, "Periorbital oedema": 10.545992373431394, "Platelet count decreased": 4.2490119531061685, "Platelet count increased": 4.857422139270834, "Pleural effusion": 9.488753746253158, "Pulmonary fibrosis": 2.498061624517764, "Pulmonary hypertension": 3.956278344060807, "Red blood cell count decreased": 2.623605299030118, "Second primary malignancy": 22.180719621427308, "Skin exfoliation": 3.3793741361913217, "Splenomegaly": 4.059251768089615, "Squamous cell carcinoma": 7.430656658134777, "Subdural haematoma": 4.243015128614345, "Therapeutic response decreased": 5.865927545672381, "Thrombocytopenia": 2.042119416828943, "White blood cell count decreased": 3.2449237429848106, "White blood cell count increased": 7.8066515084351025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/513.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/513.json
index 274eb3b1e11..6fdf96fb370 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/513.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/513.json
@@ -1 +1 @@
-{"Abdominal distension ": 27.44436965826181, "Abdominal pain ": 7.321081890619816, "Abdominal pain lower ": 8.668791532723365, "Abortion ": 146.17175789126907, "Abortion spontaneous ": 15.605549896270018, "Adnexal torsion ": 712.1203333410441, "Ascites ": 106.8557568777973, "Chest discomfort ": 3.680840228487849, "Ectopic pregnancy ": 98.07945434737492, "Haematocrit increased ": 51.5815769560383, "Haemoperitoneum ": 75.7209910932926, "Hospitalisation ": 4.756287587870593, "Hyponatraemia ": 2.146020347678118, "Incorrect dose administered ": 18.38893238001584, "Jugular vein thrombosis ": 71.13364711043621, "Ovarian cyst ": 35.56144068611211, "Ovarian enlargement ": 1103.8244496017528, "Ovarian haemorrhage ": 304.0913425839392, "Ovarian hyperstimulation syndrome ": 2471.5156252129264, "Pelvic fluid collection ": 622.36807009238, "Pleural effusion ": 16.71601558581784, "Retching ": 6.385225455519896, "Tension ": 46.24916265749008, "Uterine hyperstimulation ": 661.570138984048}
\ No newline at end of file
+{"Cytokine release syndrome": 625.5810417020712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/514.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/514.json
index 122a03de4ed..835ef832ae5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/514.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/514.json
@@ -1 +1 @@
-{"Condition aggravated ": 5.928385868020947, "Diarrhoea ": 2.5731732212931555, "Myoclonus ": 73.56009032098757, "Somnolence ": 5.328507709187519}
\ No newline at end of file
+{"Accidental overdose": 5.725508664208805, "Acute kidney injury": 2.315185461083165, "Altered state of consciousness": 3.375257157275059, "Anaphylactic shock": 2.314713020934067, "Blood glucose abnormal": 6.807152851030573, "Blood glucose decreased": 48.71665973824195, "Blood glucose increased": 6.739463185007669, "Blood pressure decreased": 3.306338907111413, "Bradycardia": 11.91358183122607, "Cardiac arrest": 22.185338824506704, "Cardiogenic shock": 33.14749217031573, "Circulatory collapse": 5.373584282813225, "Coma": 3.0211698752762173, "Coma scale abnormal": 108.83144302429626, "Compartment syndrome": 194.11095942823283, "Completed suicide": 4.21177125709921, "Diabetic ketoacidosis": 4.34660284657334, "Drug ineffective": 5.028369334432691, "Drug screen positive": 55.20627207166592, "Expired product administered": 29.898897788173056, "General physical health deterioration": 2.9611934369234327, "Haemodynamic instability": 25.63312861873641, "Hyperglycaemia": 3.664733570106926, "Hyperkalaemia": 6.978504975294022, "Hypoglycaemia": 7.743379306849417, "Hypoglycaemic coma": 11.010667654901065, "Hypoglycaemic seizure": 34.40708570720253, "Hypoglycaemic unconsciousness": 29.10304710028644, "Hypotension": 4.662905373750155, "Hypoxic-ischaemic encephalopathy": 87.4524883122731, "Ileus": 40.15298729404237, "Incorrect dose administered": 6.476510556395466, "Intentional overdose": 7.143546894706867, "Lactic acidosis": 18.29339663212248, "Loss of consciousness": 4.929344722966061, "Mental status changes": 16.45119628948413, "Metabolic acidosis": 5.638466002694288, "Overdose": 4.220962392169906, "Product dose omission issue": 2.060998830785458, "Pulmonary oedema": 3.5908463377098747, "Pulse absent": 88.60645199749415, "Pulseless electrical activity": 64.35217573762536, "Pupil fixed": 82.10159750584485, "Respiratory depression": 17.646401564870867, "Rhabdomyolysis": 7.381719612016032, "Seizure": 3.520366206589413, "Shock": 16.698931492150127, "Therapy non-responder": 4.220374984129064, "Toxicity to various agents": 4.284395064895399, "Underdose": 10.913071924340004, "Unresponsive to stimuli": 5.31235088320137, "Vasoplegia syndrome": 430.11637551698135, "Ventricular tachycardia": 9.349221107426205, "Wrong technique in product usage process": 3.338051756732825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/515.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/515.json
index 942d447c67a..2c3de6af6fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/515.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/515.json
@@ -1 +1 @@
-{"Death ": 3.9563500719015057}
\ No newline at end of file
+{"Drug ineffective": 5.558755533881448, "Product use in unapproved indication": 12.805231519371109}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/516.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/516.json
index 3a2672d252b..526b6c7ee72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/516.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/516.json
@@ -1 +1 @@
-{"Anaphylactic reaction ": 5.356348745497177, "Dizziness ": 2.3832392380405856, "Drug hypersensitivity ": 6.644100079975162, "Epistaxis ": 5.038003607299718, "Erythema ": 3.273276644604053, "Flushing ": 11.412226414164977, "Haematoma ": 11.971011002331942, "Hypotension ": 3.227803350307052, "Oesophageal carcinoma ": 63.390300370528976, "Product formulation issue ": 480.6615881764384, "Reaction to excipient ": 197.4792364666786, "Sneezing ": 37.0227655022944, "Therapeutic response unexpected ": 25.80951651850826, "Urticaria ": 3.42870808107878}
\ No newline at end of file
+{"Acute myocardial infarction": 4.219261580589798, "Adjustment disorder": 427.4883404179413, "Anxiety": 4.414400461996598, "Arthritis": 3.065367556652224, "Asthma": 25.77078757650816, "Asthmatic crisis": 14.8907051112214, "Blood cholesterol abnormal": 34.820862400272105, "Blood immunoglobulin E increased": 49.41222420313562, "Bronchial obstruction": 46.3832179390269, "Bronchitis": 2.81319337974205, "Chest discomfort": 8.695216723561321, "Choking": 12.690589165002294, "Chronic obstructive pulmonary disease": 27.272757732136984, "Coronary artery disease": 4.705417660094238, "Cough": 6.64700114403688, "Crepitations": 44.63352807829998, "Depressed mood": 18.15735935340084, "Discomfort": 13.775107205082568, "Drug intolerance": 9.480612739064918, "Dyspnoea": 4.943351617344426, "Emphysema": 11.609128297957133, "Erythema nodosum": 22.3821710176236, "Faeces discoloured": 5.918613933203575, "Full blood count abnormal": 66.17129266597702, "Gastrooesophageal reflux disease": 18.322820597305565, "Glaucoma": 12.489912142733584, "Haemoglobin decreased": 5.51214585661806, "Hilar lymphadenopathy": 109.3371858324765, "Hip fracture": 4.21348263076589, "Hospitalisation": 4.657433800374021, "Hypercholesterolaemia": 80.32487096122237, "Hypersensitivity": 2.0262044747623738, "Hyperthyroidism": 3.85390579751219, "Hypogammaglobulinaemia": 34.792259578287414, "Infection": 6.229394483446552, "Laryngospasm": 19.779587415293364, "Loss of personal independence in daily activities": 28.87663885538977, "Lower respiratory tract infection": 2.5610268125243865, "Nervousness": 3.25780036988099, "Neutrophil count decreased": 8.062605181958121, "Obesity": 66.4218957243778, "Obstructive airways disorder": 44.02344786435396, "Oxygen saturation decreased": 4.032244365563122, "Productive cough": 35.22558742791208, "Pulmonary mass": 16.43957354278706, "Respiratory disorder": 4.817130224566473, "Respiratory symptom": 25.36879956410619, "Rhinitis allergic": 175.31064955010729, "Sinus congestion": 68.02362408683393, "Sleep disorder": 2.3973991503472942, "Sleep disorder due to a general medical condition": 134.64073509343035, "Sputum discoloured": 81.47849535863254, "Therapeutic product effect incomplete": 33.59464907354145, "Total lung capacity increased": 632.3955860102072, "Upper-airway cough syndrome": 75.31106485651519, "Wheezing": 41.1164674840245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/517.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/517.json
index 6bd2fb3d6c0..aef0625b417 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/517.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/517.json
@@ -1 +1 @@
-{"Agitation ": 11.156048848624554, "Completed suicide ": 17.75102651727286, "Drug ineffective ": 3.625738975710165, "Hyperhidrosis ": 4.218709718398258, "Hypotension ": 4.81905046637191, "Intentional overdose ": 10.284906114126846, "Intentional product misuse ": 11.072050637112987, "Off label use ": 3.288013869535126, "Toxicity to various agents ": 5.460121416690418}
\ No newline at end of file
+{"Ectopic pregnancy": 32649.084267910934}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/518.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/518.json
index b2c912aafb4..c6cfedbd46c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/518.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/518.json
@@ -1 +1 @@
-{"Drug ineffective ": 3.820263992439816, "Product use in unapproved indication ": 4.319829252134142, "Psoriasis ": 19.823778766041663}
\ No newline at end of file
+{"Arthritis": 6.00074716211868, "Colitis ulcerative": 8.373608110345094, "Drug ineffective": 3.9024451890725778, "Infection": 5.081654607398911, "Lymphoproliferative disorder": 171.54023905889187, "Pneumonia": 2.6547594146589923, "Psoriasis": 17.33678070325074, "Psoriatic arthropathy": 8.370060998611207, "Rheumatoid arthritis": 6.935613258051929, "Therapeutic product effect decreased": 6.12036585884248}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/519.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/519.json
index 4f57d9da287..10dd831a10c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/519.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/519.json
@@ -1 +1 @@
-{"Acute kidney injury ": 37.949377586317965, "Hypophosphataemia ": 705.89987823997, "Rhabdomyolysis ": 216.35069088426985}
\ No newline at end of file
+{"Abdominal distension": 27.120681776286062, "Abdominal pain": 7.234733059706771, "Abdominal pain lower": 8.566764922629247, "Abortion": 144.45015550521677, "Abortion spontaneous": 15.42175663392469, "Adnexal torsion": 703.7384510481628, "Ascites": 105.59424441643765, "Chest discomfort": 3.853945048882799, "Ectopic pregnancy": 96.92512928260922, "Haematocrit increased": 50.97458676897165, "Haemoperitoneum": 74.82980670656231, "Hospitalisation": 4.700296232353882, "Hyponatraemia": 2.1207629217296726, "Incorrect dose administered": 18.172259047915965, "Jugular vein thrombosis": 70.29657831827883, "Ovarian cyst": 35.14290471709158, "Ovarian enlargement": 1090.829249503586, "Ovarian haemorrhage": 300.5133259276359, "Ovarian hyperstimulation syndrome": 2442.1759875016805, "Pelvic fluid collection": 615.0420967746273, "Pleural effusion": 16.517533288779696, "Retching": 6.3100895518501545, "Tension": 45.7047173502306, "Uterine hyperstimulation": 653.7823168535034}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/52.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/52.json
index 1f6ff350c07..a59e4a668dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/52.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/52.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.0949800380869155, "Abortion induced ": 7.844961259580289, "Adjustment disorder ": 818.985859999993, "Affect lability ": 133.22036544089312, "Amnesia ": 7.837733242049719, "Angina pectoris ": 20.746562321922468, "Anxiety ": 6.056960094960443, "Aphasia ": 43.04666273680289, "Arterial occlusive disease ": 138.6771059963094, "Arthritis ": 14.833735459789397, "Atrioventricular block ": 4.502040066685692, "Blood potassium increased ": 4.446608314713722, "Blood pressure inadequately controlled ": 76.07040974156008, "Blood pressure increased ": 6.847405359181285, "Cardiac failure ": 3.0825206504263787, "Cardiac failure chronic ": 12.410163552259036, "Cardiac septal defect ": 66.91960566720492, "Carotid artery thrombosis ": 1761.9388493684608, "Cataract ": 21.68466296111506, "Cerebrovascular accident ": 10.399097763414634, "Chest discomfort ": 5.893821820609416, "Cognitive disorder ": 11.179018053497956, "Concomitant disease progression ": 66.99145028005182, "Confusional state ": 8.285165651601863, "Congenital cardiovascular anomaly ": 34.63964857021566, "Conjoined twins ": 921.3235149663088, "Contusion ": 6.2339418931359285, "Coordination abnormal ": 108.41998079298318, "Cough ": 3.16219596255814, "Cystitis ": 45.17170950493468, "Depressed mood ": 8.57322193773132, "Diabetes mellitus inadequate control ": 16.3668090258124, "Dysarthria ": 33.258109450506424, "Dysphagia ": 17.41312533918719, "Eating disorder ": 92.83224784284614, "Electrolyte imbalance ": 4.600457955448892, "Exercise tolerance decreased ": 41.13310261376232, "Fall ": 7.176319497335696, "Foetal exposure during pregnancy ": 2.6157851035844315, "Gangrene ": 201.6938769709754, "Gastrointestinal disorder ": 11.276925693241903, "Haemoglobin abnormal ": 19.86643666036015, "Heart disease congenital ": 9.782031862423205, "Hemiparesis ": 73.63442192676031, "Hemiplegia ": 122.12495515961616, "Hyperaldosteronism ": 202.89714715452092, "Hyperkalaemia ": 3.851214217571012, "Hypertension ": 3.5478962905442, "Hypertensive crisis ": 3.1052416624331927, "Immune thrombocytopenia ": 4.961768311648302, "Impaired work ability ": 9.11416505936791, "Low birth weight baby ": 3.705976736931941, "Medication error ": 6.195840590800977, "Mobility decreased ": 9.275322466282208, "Motor dysfunction ": 50.13723904052972, "Mouth haemorrhage ": 10.81951499422057, "Multiple drug therapy ": 163.4984966064616, "Muscle spasticity ": 52.58602668983142, "Muscular weakness ": 4.501693007252407, "Neurologic neglect syndrome ": 823.7237790575595, "Oedema peripheral ": 6.311166401519785, "Personality disorder ": 173.58498184190398, "Sensory loss ": 41.67292585129446, "Skin haemorrhage ": 11.389322364990765, "Treatment noncompliance ": 11.479566286681106, "Truncus arteriosus persistent ": 426.6712228481429, "Vascular calcification ": 234.9042493389092, "Ventricular septal defect ": 7.093957810134874, "Ventricular tachycardia ": 3.897876771030065}
\ No newline at end of file
+{"Acute coronary syndrome": 2.617058852760312, "Acute generalised exanthematous pustulosis": 2.690328480427259, "Acute kidney injury": 3.555821019126201, "Acute pulmonary oedema": 2.6168619496727743, "Acute respiratory failure": 2.7962291805598927, "Alanine aminotransferase increased": 2.091530432423037, "Anaemia": 6.453276168811002, "Aspartate aminotransferase increased": 2.2557852986376656, "Bicytopenia": 8.5834952554688, "Blood creatinine increased": 2.987016799152558, "Blood magnesium decreased": 3.086813710840838, "Bone marrow failure": 20.46912666549953, "C-reactive protein increased": 2.333829419537141, "Cellulitis": 2.0837567409464275, "Cerebral infarction": 2.3467513619486966, "Cholestasis": 2.7498367473777408, "Colitis": 5.33372639244486, "Colitis ischaemic": 3.015439272301613, "Congenital aplasia": 34.55065022058972, "Conjunctivitis": 4.653762108630027, "Creatinine renal clearance decreased": 10.038157603883564, "Cytopenia": 2.4654490353272247, "Death": 2.133419272886312, "Decreased appetite": 2.4469302198966942, "Dehydration": 2.5152525921022595, "Dermatitis": 3.3806169212153816, "Dermatitis bullous": 3.992593480382662, "Dermatitis exfoliative generalised": 2.545215994788846, "Dermo-hypodermitis": 41.13463772213367, "Disease progression": 2.222518193787234, "Disseminated intravascular coagulation": 4.687109409484428, "Drug eruption": 2.247294419904118, "Enteritis": 6.178735748091023, "Enterocolitis": 6.342254726887617, "Erysipelas": 9.190805937962253, "Eyelid oedema": 2.545970090401545, "Febrile bone marrow aplasia": 45.737569991035, "Febrile neutropenia": 11.926965603202683, "Gastrointestinal necrosis": 7.540149650996057, "Gastrointestinal perforation": 4.130067607171318, "Gastrointestinal toxicity": 4.251609047365809, "General physical health deterioration": 3.3219538157415496, "Generalised oedema": 3.466945943486511, "Granulocytopenia": 2.3584151095808545, "Haematocrit decreased": 2.4102747656145813, "Haematotoxicity": 18.18047000409302, "Haemoglobin decreased": 2.6613181790944767, "Haemolytic anaemia": 2.222335508831179, "Haemoptysis": 4.193107464974718, "Hepatic cytolysis": 6.05624656232113, "Hepatocellular injury": 4.678925388619213, "Hiccups": 5.019894154420486, "Hospice care": 17.62796954419729, "Hypertransaminasaemia": 6.236898858634018, "Hypoalbuminaemia": 3.3909226247658046, "Hypocalcaemia": 2.173852545930351, "Hypomagnesaemia": 2.4718487309531003, "Hypophagia": 2.0094844354584547, "Ileus": 2.156734372783618, "Immune-mediated enterocolitis": 3.896940114643466, "Immune-mediated hepatic disorder": 11.472469817689513, "Immune-mediated hepatitis": 5.003016610445751, "Immune-mediated lung disease": 5.836701153509392, "Infectious pleural effusion": 9.738364710619626, "Interstitial lung disease": 15.30992891974501, "Intestinal perforation": 4.906375220694746, "Ischaemic stroke": 2.3104260269948287, "Lacrimation increased": 3.733165771183845, "Large intestine perforation": 3.800956215802575, "Left ventricular dysfunction": 2.708297761606201, "Leukoencephalopathy": 5.458262979281818, "Leukopenia": 5.363617814284812, "Lichenoid keratosis": 7.922876019064592, "Liver disorder": 2.3133165310214348, "Lung adenocarcinoma": 7.515945786741905, "Lung disorder": 4.001933990182212, "Lung infiltration": 2.6404197018067697, "Lymphocyte count decreased": 2.50187372835504, "Lymphoedema": 2.48076188490676, "Malignant neoplasm progression": 22.685301763025528, "Malignant pleural effusion": 11.283119446394767, "Metastases to central nervous system": 2.985369263592658, "Metastases to meninges": 9.324240708755696, "Mucosal inflammation": 20.667109300032763, "Myelosuppression": 8.335613859382482, "Myositis": 2.1465364922288632, "Neoplasm progression": 10.840530994796836, "Nephritis": 9.359551566284056, "Nephrogenic diabetes insipidus": 5.255493209810065, "Nephropathy toxic": 8.349366848945547, "Nephrotic syndrome": 2.9074035701178365, "Neutropenia": 8.53182591618638, "Neutropenic sepsis": 13.71526175504257, "Neutrophil count decreased": 6.9106502276361645, "Non-small cell lung cancer": 7.367040542798005, "Oedema peripheral": 2.9469609189047974, "Oesophageal candidiasis": 4.050268647332098, "Oesophagitis": 4.193420773445412, "Off label use": 3.983197649038876, "Oral candidiasis": 2.75204136774328, "Organising pneumonia": 6.0488465658707575, "Osteonecrosis of jaw": 3.544968527356245, "Ototoxicity": 7.685290052827204, "Pancytopenia": 19.1483356397338, "Panniculitis": 3.682938896503301, "Performance status decreased": 3.5968138033072456, "Pericardial effusion": 2.409438826500479, "Periorbital oedema": 2.177206815011948, "Peripheral ischaemia": 3.4355198825332045, "Peripheral sensory neuropathy": 2.454926443280172, "Peritonitis": 3.129826647901603, "Platelet count decreased": 5.816457706133234, "Pleural effusion": 5.272739285108858, "Pneumonia bacterial": 2.7835395416865327, "Pneumonitis": 16.13262891593914, "Pneumothorax": 3.910957483134511, "Pulmonary fibrosis": 2.1651331781184164, "Pulmonary toxicity": 4.386769903852649, "Purpura": 2.9734339382927057, "Radiation pneumonitis": 26.29113537833904, "Rash maculo-papular": 3.498597603812271, "Recall phenomenon": 104.6420389196962, "Renal disorder": 2.3019539387552643, "Renal failure": 3.8701610265979496, "Renal impairment": 3.1511603449487717, "Renal tubular necrosis": 4.194583772143596, "Respiratory failure": 2.7729638301706743, "Sepsis": 3.4931073339188154, "Septic shock": 6.783709797899157, "Skin hyperpigmentation": 6.506928888966977, "Skin toxicity": 8.05181352612892, "Small intestinal perforation": 13.07884455767921, "Staphylococcal sepsis": 4.528023227796149, "Stomatitis": 3.789363909776583, "Therapy partial responder": 5.731171086318192, "Thrombocytopenia": 8.328163847556848, "Thrombophlebitis migrans": 30.041564853641983, "Thrombotic thrombocytopenic purpura": 2.457834580901952, "Toxic epidermal necrolysis": 2.695801025604946, "Toxic skin eruption": 5.678609767375122, "Transaminases increased": 3.025894147080043, "Tubulointerstitial nephritis": 8.117682543728291, "White blood cell count decreased": 3.7213138808959054}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/520.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/520.json
index 2cb93c5cb2d..7433235730d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/520.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/520.json
@@ -1 +1 @@
-{"Alopecia ": 4.504042453475993, "Anaemia ": 3.588244028722119, "Aphthous ulcer ": 3.443729630799968, "Aspartate aminotransferase increased ": 2.167362873166672, "Asthenia ": 2.35350036366075, "Ataxia ": 2.2111469409884283, "Cardiac failure ": 3.862892276276353, "Conjunctivitis ": 2.4274476494459893, "Cystitis haemorrhagic ": 7.96119926418608, "Decreased appetite ": 2.1753735611164804, "Disseminated intravascular coagulation ": 5.112163176540674, "Drug-induced liver injury ": 3.1132428467023847, "Enterocolitis ": 8.024529103344896, "Febrile neutropenia ": 62.68894754290422, "Granulocytopenia ": 4.471960678263996, "Hepatic cirrhosis ": 2.8865913712369187, "Hepatic failure ": 3.975270799516212, "Hepatic function abnormal ": 3.643069809509709, "Hyperbilirubinaemia ": 2.5689827564013554, "Hyperpyrexia ": 2.8565623223516066, "Hypertransaminasaemia ": 10.720124075044732, "Hypoacusis ": 2.378541856073025, "Interstitial lung disease ": 20.86194701529745, "Leukopenia ": 21.3628244842576, "Lymphopenia ": 4.667670654744531, "Malignant neoplasm progression ": 12.269189941285596, "Metastases to central nervous system ": 6.281793230317255, "Mouth ulceration ": 3.0329397701465703, "Mucosal inflammation ": 16.62397688200028, "Myelosuppression ": 30.660202447203687, "Neuropathy peripheral ": 15.915323204043828, "Neurotoxicity ": 6.94467427494983, "Neutropenia ": 31.147048360758237, "Neutropenic sepsis ": 14.272453684068877, "Neutrophil count decreased ": 22.60674901234608, "Palmar-plantar erythrodysaesthesia syndrome ": 2.6372436357367146, "Pancytopenia ": 3.466871866847367, "Peripheral sensory neuropathy ": 11.64383512958491, "Pharyngitis ": 3.576763952068084, "Platelet count decreased ": 2.542775686719008, "Pleural effusion ": 3.786833643269671, "Pneumocystis jirovecii pneumonia ": 4.413919403031031, "Pneumonia ": 2.086402959972697, "Pneumonitis ": 5.133553341464911, "Pneumothorax ": 10.589825367498312, "Polyneuropathy ": 11.215632563580252, "Pseudocirrhosis ": 176.10370880440905, "Red blood cell count decreased ": 2.330319721118961, "Sepsis ": 5.035979733385404, "Septic shock ": 3.290143991492804, "Stevens-Johnson syndrome ": 2.142005525052563, "Stomatitis ": 17.90495874411765, "Thrombocytopenia ": 3.824680569627609, "White blood cell count decreased ": 14.261058894477518}
\ No newline at end of file
+{"Condition aggravated": 5.928385868020947, "Diarrhoea": 2.5731517482210045, "Myoclonus": 73.56009032098757, "Somnolence": 5.328448975845081}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/521.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/521.json
index ee941d0dfcf..ed76c42757a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/521.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/521.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 2.697762741304837, "Alpha 1 foetoprotein increased ": 16.875268978623797, "Ammonia increased ": 4.73377396540167, "Anaemia ": 3.0814194850066685, "Anger ": 2.0121463620690245, "Ascites ": 15.005517187332382, "Atrioventricular block second degree ": 4.984759500746836, "Autoimmune hepatitis ": 3.150997217739466, "Blood bilirubin increased ": 4.98981893630443, "Blood creatinine increased ": 2.042799798905388, "Bradycardia ": 2.1070025351553063, "Cholangiocarcinoma ": 17.663420147562075, "Cryoglobulinaemia ": 30.674879948406403, "Drug ineffective ": 10.46466578496998, "Drug interaction ": 2.525806984118276, "Drug resistance ": 4.306003531993655, "Encephalopathy ": 4.8973122787396175, "Endotracheal intubation ": 3.7339567196810086, "Fanconi syndrome acquired ": 3.110091470457843, "Gastritis erosive ": 4.275375886103681, "Genotype drug resistance test positive ": 209.12966486986124, "Glomerular filtration rate decreased ": 9.59118611304434, "Haemolysis ": 2.5010698339926307, "Haemorrhagic stroke ": 3.049237843951357, "Hepatic cancer ": 14.97648138783986, "Hepatic cancer recurrent ": 229.73980363895225, "Hepatic cirrhosis ": 17.77469453588154, "Hepatic encephalopathy ": 20.57371811762984, "Hepatic failure ": 8.15056300473802, "Hepatic lesion ": 5.663877675850996, "Hepatic mass ": 20.32763330193152, "Hepatic pain ": 5.623214282279865, "Hepatitis B reactivation ": 30.71656075311177, "Hepatitis C ": 209.96740766911051, "Hepatitis C RNA positive ": 49.2195562710512, "Hepatitis C virus test positive ": 145.48517654250932, "Hepatocellular carcinoma ": 58.42611373237201, "Hepatorenal syndrome ": 12.932037305789096, "Hyperbilirubinaemia ": 4.510867606832952, "Hypophosphataemia ": 3.0594080189507435, "Immune system disorder ": 2.7879453791831583, "Incorrect product administration duration ": 3.625035421755349, "Intentional dose omission ": 4.826400603707151, "Jaundice ": 2.213216338336152, "Liver transplant ": 40.72665666149275, "Lymphoma ": 2.370026319083788, "Metastases to lymph nodes ": 3.209468068523524, "Oesophageal varices haemorrhage ": 39.19669618351153, "Paranoia ": 2.074809780275474, "Plantar fasciitis ": 14.933772300369856, "Portal vein thrombosis ": 9.431582628508904, "Product use complaint ": 4.306244241493999, "Pulmonary arterial hypertension ": 2.038853115278949, "Renal impairment ": 2.469915926328785, "Respiration abnormal ": 3.522637375767661, "Sciatica ": 2.650120604321654, "Septic shock ": 2.443701889236736, "Spinal stenosis ": 5.399517603808179, "Subarachnoid haemorrhage ": 4.102340497844847, "Sudden death ": 4.510365483104159, "Synovial cyst ": 10.089949488553408, "Temperature regulation disorder ": 3.95601656254784, "Therapeutic response unexpected ": 2.027770948388397, "Therapy cessation ": 5.07525202273341, "Therapy non-responder ": 3.3262392671171157, "Thyroid disorder ": 2.6469330240135944, "Treatment failure ": 35.904955202169035, "Treatment noncompliance ": 4.330842342696448, "Unevaluable event ": 2.495931668685869, "Upper gastrointestinal haemorrhage ": 2.9747165137114364, "Varices oesophageal ": 12.72467366239956, "Viral load increased ": 5.1893987753290105, "Viral mutation identified ": 94.03920278309782, "Virologic failure ": 14.99916011346792}
\ No newline at end of file
+{"Death": 3.9563500719015057}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/522.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/522.json
index 9e26dfeeb6e..7c54a8de435 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/522.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/522.json
@@ -1 +1 @@
-{}
\ No newline at end of file
+{"Anaphylactic reaction": 5.3562349269588125, "Dizziness": 2.3832226932367915, "Drug hypersensitivity": 6.644100079975162, "Epistaxis": 5.038003607299718, "Erythema": 3.273244630815263, "Flushing": 11.412226414164977, "Haematoma": 11.971011002331942, "Hypotension": 3.227728735031844, "Oesophageal carcinoma": 63.390300370528976, "Product formulation issue": 480.6615881764384, "Reaction to excipient": 197.4792364666786, "Sneezing": 37.0227655022944, "Therapeutic response unexpected": 25.80951651850826, "Urticaria": 3.428672954773432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/523.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/523.json
index 30d7e5124e2..a3d694e153a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/523.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/523.json
@@ -1 +1 @@
-{"Anti factor VIII antibody positive ": 2526.0794837119424, "Factor VIII inhibition ": 2562.360690650658, "Haemarthrosis ": 316.6600559403955}
\ No newline at end of file
+{"Agitation": 11.156048848624554, "Completed suicide": 17.75102651727286, "Drug ineffective": 3.625712174086503, "Hyperhidrosis": 4.218709718398258, "Hypotension": 4.818939067173309, "Intentional overdose": 10.284906114126846, "Intentional product misuse": 11.072050637112987, "Off label use": 3.2878843729141085, "Toxicity to various agents": 5.460121416690418}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/524.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/524.json
index 0f368ac3655..fa7c040d056 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/524.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/524.json
@@ -1 +1 @@
-{"Bradycardia ": 16.132973088012957, "Bronchiolitis ": 88.99038388210653, "Drug titration error ": 2301.0846467385527, "Hypoglycaemia ": 23.191139644224226, "Hypoglycaemic seizure ": 309.97633300646106, "Hypotension ": 2.223812821691633, "Irritability ": 11.936885285375954, "Off label use ": 13.713121645871585, "Product administered to patient of inappropriate age ": 229.77071380582444, "Product use issue ": 19.676594100050394, "Sleep disorder ": 21.843204118528053, "Somnolence ": 2.54127000041944}
\ No newline at end of file
+{"Drug ineffective": 3.8202357523113295, "Product use in unapproved indication": 4.31969455271971, "Psoriasis": 19.823778766041663}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/525.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/525.json
index aa9816f8bc0..dbc9789bbff 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/525.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/525.json
@@ -1 +1 @@
-{"Activated partial thromboplastin time prolonged ": 72.05148900873449, "Acute myocardial infarction ": 3.300221122539162, "Blood urine present ": 12.771701943754934, "Cerebral haemorrhage ": 3.915056627534883, "Cerebral infarction ": 4.473312702598258, "Contusion ": 5.318568596240191, "Drug level decreased ": 11.93836889004657, "Drug level increased ": 4.259139563805238, "Drug specific antibody present ": 158.56430117260803, "Epistaxis ": 4.401989015957592, "Fall ": 6.730830472188859, "Gastric haemorrhage ": 13.331516630039411, "Gastrointestinal haemorrhage ": 6.294670412179276, "Gingival bleeding ": 13.547923342503749, "Haemarthrosis ": 398.94422635045646, "Haematoma ": 10.673501489683895, "Haematoma muscle ": 32.78587640673578, "Haematuria ": 5.609204308743358, "Haemorrhage ": 77.88142669776944, "Haemorrhage intracranial ": 6.886895254851355, "Head injury ": 32.61547141284012, "Injection site reaction ": 2.481843720567228, "Injury ": 8.666863564110663, "Intentional product use issue ": 3.748389255691916, "Joint injury ": 13.858352433988214, "Joint swelling ": 2.0475177380630503, "Ligament sprain ": 20.438175479098213, "Limb injury ": 8.90856941147081, "Mouth haemorrhage ": 45.31209499041631, "Muscle haemorrhage ": 368.8851761018944, "Nephritis ": 22.588099575935384, "Nephrolithiasis ": 4.4243755029452805, "No adverse event ": 4.966154478585073, "Post procedural haemorrhage ": 26.97633434903145, "Procedural haemorrhage ": 33.57126784887463, "Renal haemorrhage ": 44.88643496986472, "Road traffic accident ": 3.418749076493913, "Skin laceration ": 15.78821221592371, "Spontaneous haemorrhage ": 180.42468064031465, "Subdural haematoma ": 5.7370897854496885, "Therapeutic response decreased ": 3.0126749314159555, "Traumatic haemorrhage ": 261.1155952554108, "Underdose ": 4.63283956594904}
\ No newline at end of file
+{"Acute kidney injury": 37.949377586317965, "Hypophosphataemia": 705.89987823997, "Rhabdomyolysis": 216.35069088426985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/526.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/526.json
index d37746dbc6b..3ce4c1293f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/526.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/526.json
@@ -1 +1 @@
-{"Acquired aminoaciduria ": 2329.632271930392, "Alanine aminotransferase increased ": 6.913328566193478, "Aminoaciduria ": 731.2622665216284, "Ascites ": 2.3581492124856798, "Aspartate aminotransferase increased ": 2.7141186718930794, "Back pain ": 4.143619523804344, "Beta 2 microglobulin increased ": 289.51718883776385, "Beta 2 microglobulin urine increased ": 323.52143498466376, "Blood alkaline phosphatase increased ": 28.16834807378762, "Blood bilirubin increased ": 3.3453950080861063, "Blood creatine phosphokinase MB increased ": 37.52840267058623, "Blood creatine phosphokinase increased ": 2.592709736848435, "Blood creatinine increased ": 8.54923707554949, "Blood phosphorus decreased ": 391.6936320071961, "Blood potassium decreased ": 4.202519375968437, "Blood uric acid decreased ": 225.6894386343257, "Bone metabolism disorder ": 190.04427165810185, "Bone pain ": 13.581229409506877, "Creatinine renal clearance decreased ": 21.44767353389637, "Disease recurrence ": 2.2589199340022503, "Drug ineffective ": 2.209775248500202, "Drug resistance ": 48.16925443337597, "Drug tolerance ": 15.61960145484399, "Fanconi syndrome ": 307.7260100795215, "Fanconi syndrome acquired ": 486.0392539776995, "Femoral neck fracture ": 48.62599775848373, "Femur fracture ": 5.182428961977306, "Foot fracture ": 5.8403118744172975, "Fracture ": 10.55615778216707, "Gait disturbance ": 3.527330392331271, "Genotype drug resistance test positive ": 38.522496795404365, "Glomerular filtration rate decreased ": 9.909123720359222, "Glucose urine present ": 100.6072620648826, "Glycosuria ": 47.59055984878525, "Hepatic cancer ": 18.086266146471115, "Hepatic cirrhosis ": 8.428477113072669, "Hepatic failure ": 3.7644806714094976, "Hepatic steatosis ": 4.225463456311646, "Hepatitis ": 3.6994466954406735, "Hepatitis B ": 40.75201156813115, "Hepatitis B DNA assay positive ": 191.44061970449027, "Hepatitis B DNA increased ": 338.42826030452915, "Hepatitis B reactivation ": 44.65817401307872, "Hepatocellular carcinoma ": 12.485046651037486, "Hyperphosphatasaemia ": 925.0294550685296, "Hypophosphataemia ": 389.2838046527665, "Hypophosphataemic osteomalacia ": 1033.3298314677031, "Hypouricaemia ": 1112.684669710175, "Jaundice ": 3.5537000308467173, "Liver disorder ": 2.052152721024981, "Metabolic acidosis ": 9.569751333342657, "Movement disorder ": 2.1368420258205894, "Multiple fractures ": 3.6000743399115893, "Muscular weakness ": 2.943874475443774, "Musculoskeletal chest pain ": 6.291496500752625, "Nephropathy ": 2.702581694389534, "Nephropathy toxic ": 6.925310611766496, "Osteomalacia ": 645.4999120606287, "Osteoporosis ": 7.13236119592556, "Pathogen resistance ": 7.553551912943149, "Pathological fracture ": 49.06039601632977, "Product complaint ": 3.57557203930012, "Protein urine present ": 28.01542513836638, "Proteinuria ": 13.164315772820816, "Renal disorder ": 9.788483822973008, "Renal failure ": 2.164966829025518, "Renal function test abnormal ": 23.30656627631284, "Renal glycosuria ": 1245.135526670312, "Renal impairment ": 15.278515022120454, "Renal tubular acidosis ": 57.90662626641055, "Renal tubular disorder ": 98.07129314915124, "Renal tubular dysfunction ": 103.9915162946266, "Rib fracture ": 16.381379774631004, "Spinal compression fracture ": 9.72577058560791, "Therapeutic response decreased ": 8.233763100962967, "Therapy non-responder ": 2.715086410649297, "Tibia fracture ": 18.285661805768235, "Transaminases increased ": 2.0754970308692737, "Tubulointerstitial nephritis ": 6.974678317951045, "Urine calcium increased ": 170.04222116763145, "Urine phosphorus increased ": 1118.0887978753017, "Viral infection ": 3.203725538308833, "Viral load increased ": 73.73402075593185, "Viral mutation identified ": 52.85393391499872, "Virologic failure ": 12.064851630748649}
\ No newline at end of file
+{"Alopecia": 4.504042453475993, "Anaemia": 3.588244028722119, "Aphthous ulcer": 3.443729630799968, "Aspartate aminotransferase increased": 2.167362873166672, "Asthenia": 2.3534066783080188, "Ataxia": 2.2111469409884283, "Cardiac failure": 3.862539258053257, "Conjunctivitis": 2.4274476494459893, "Cystitis haemorrhagic": 7.96119926418608, "Decreased appetite": 2.175352446437812, "Disseminated intravascular coagulation": 5.112163176540674, "Drug-induced liver injury": 3.1130529569514565, "Enterocolitis": 8.024529103344896, "Febrile neutropenia": 62.68894754290422, "Granulocytopenia": 4.470671594109228, "Hepatic cirrhosis": 2.8865913712369187, "Hepatic failure": 3.975270799516212, "Hepatic function abnormal": 3.643069809509709, "Hyperbilirubinaemia": 2.5689827564013554, "Hyperpyrexia": 2.8565623223516066, "Hypertransaminasaemia": 10.720124075044732, "Hypoacusis": 2.378341657653164, "Interstitial lung disease": 20.86194701529745, "Leukopenia": 21.360111492767484, "Lymphopenia": 4.667670654744531, "Malignant neoplasm progression": 12.269189941285596, "Metastases to central nervous system": 6.281793230317255, "Mouth ulceration": 3.0329397701465703, "Mucosal inflammation": 16.62397688200028, "Myelosuppression": 30.660202447203687, "Neuropathy peripheral": 15.914837362054543, "Neurotoxicity": 6.94467427494983, "Neutropenia": 31.145694373677497, "Neutropenic sepsis": 14.272453684068877, "Neutrophil count decreased": 22.60674901234608, "Palmar-plantar erythrodysaesthesia syndrome": 2.6372436357367146, "Pancytopenia": 3.466871866847367, "Peripheral sensory neuropathy": 11.64383512958491, "Pharyngitis": 3.575939261741412, "Platelet count decreased": 2.542775686719008, "Pleural effusion": 3.7864846123495512, "Pneumocystis jirovecii pneumonia": 4.413919403031031, "Pneumonia": 2.086402959972697, "Pneumonitis": 5.133553341464911, "Pneumothorax": 10.589825367498312, "Polyneuropathy": 11.215632563580252, "Pseudocirrhosis": 176.10370880440905, "Red blood cell count decreased": 2.330319721118961, "Sepsis": 5.035979733385404, "Septic shock": 3.290143991492804, "Stevens-Johnson syndrome": 2.142005525052563, "Stomatitis": 17.90495874411765, "Thrombocytopenia": 3.8243203367432006, "White blood cell count decreased": 14.261058894477518}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/527.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/527.json
index 100561bd49c..1a1e9662a18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/527.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/527.json
@@ -1 +1 @@
-{"Abdominal pain ": 3.9519428340301377, "Drug interaction ": 6.361007207976812, "Overdose ": 4.36787360081528}
\ No newline at end of file
+{"Acute hepatic failure": 2.697762741304837, "Alpha 1 foetoprotein increased": 16.875268978623797, "Ammonia increased": 4.73377396540167, "Anaemia": 3.0814194850066685, "Anger": 2.0121463620690245, "Ascites": 15.005517187332382, "Atrioventricular block second degree": 4.984759500746836, "Autoimmune hepatitis": 3.150997217739466, "Blood bilirubin increased": 4.98981893630443, "Blood creatinine increased": 2.042799798905388, "Bradycardia": 2.106936406079877, "Cholangiocarcinoma": 17.663420147562075, "Cryoglobulinaemia": 30.674879948406403, "Drug ineffective": 10.464587799648458, "Drug interaction": 2.525806984118276, "Drug resistance": 4.306003531993655, "Encephalopathy": 4.8973122787396175, "Endotracheal intubation": 3.7339567196810086, "Fanconi syndrome acquired": 3.110091470457843, "Gastritis erosive": 4.270744463220554, "Genotype drug resistance test positive": 209.12966486986124, "Glomerular filtration rate decreased": 9.59118611304434, "Haemolysis": 2.5010698339926307, "Haemorrhagic stroke": 3.049237843951357, "Hepatic cancer": 14.97648138783986, "Hepatic cancer recurrent": 229.73980363895225, "Hepatic cirrhosis": 17.77469453588154, "Hepatic encephalopathy": 20.57371811762984, "Hepatic failure": 8.15056300473802, "Hepatic lesion": 5.663877675850996, "Hepatic mass": 20.32763330193152, "Hepatic pain": 5.623214282279865, "Hepatitis B reactivation": 30.71656075311177, "Hepatitis C": 209.96740766911051, "Hepatitis C RNA positive": 49.2195562710512, "Hepatitis C virus test positive": 145.48517654250932, "Hepatocellular carcinoma": 58.42611373237201, "Hepatorenal syndrome": 12.932037305789096, "Hyperbilirubinaemia": 4.510867606832952, "Hypophosphataemia": 3.0594080189507435, "Immune system disorder": 2.7879453791831583, "Incorrect product administration duration": 3.625035421755349, "Intentional dose omission": 4.826400603707151, "Jaundice": 2.213216338336152, "Liver transplant": 40.72665666149275, "Lymphoma": 2.370026319083788, "Metastases to lymph nodes": 3.209468068523524, "Oesophageal varices haemorrhage": 39.19669618351153, "Paranoia": 2.074809780275474, "Plantar fasciitis": 14.933772300369856, "Portal vein thrombosis": 9.431582628508904, "Product use complaint": 4.306244241493999, "Pulmonary arterial hypertension": 2.038853115278949, "Renal impairment": 2.469915926328785, "Respiration abnormal": 3.522637375767661, "Sciatica": 2.650120604321654, "Septic shock": 2.443701889236736, "Spinal stenosis": 5.399517603808179, "Subarachnoid haemorrhage": 4.102340497844847, "Sudden death": 4.510365483104159, "Synovial cyst": 10.089949488553408, "Temperature regulation disorder": 3.95601656254784, "Therapeutic response unexpected": 2.027770948388397, "Therapy cessation": 5.07525202273341, "Therapy non-responder": 3.325948007755163, "Thyroid disorder": 2.6469330240135944, "Treatment failure": 35.904955202169035, "Treatment noncompliance": 4.330842342696448, "Unevaluable event": 2.495931668685869, "Upper gastrointestinal haemorrhage": 2.973907386076198, "Varices oesophageal": 12.72467366239956, "Viral load increased": 5.1893987753290105, "Viral mutation identified": 94.03920278309782, "Virologic failure": 14.99916011346792}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/528.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/528.json
index 3586c743bb8..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/528.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/528.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 5.563235931985917, "Alopecia ": 2.758326892691253, "Alopecia areata ": 5.853647743634364, "Aortitis ": 19.790133136971345, "Blood lactate dehydrogenase increased ": 2.124833871112354, "Blood magnesium decreased ": 4.846376007144799, "Breast cancer metastatic ": 10.083868526044066, "Breast cancer recurrent ": 30.195068805959075, "Cardiac disorder ": 2.871957835538458, "Cardiac dysfunction ": 74.86613243387622, "Cardiac failure ": 14.30394070145912, "Cardiac failure acute ": 7.144756622736439, "Cardiac failure congestive ": 2.782964151357341, "Cardiomyopathy ": 14.65855317058424, "Cardiotoxicity ": 33.84908456206, "Dermatitis acneiform ": 4.6161009540491165, "Diarrhoea ": 3.973989721985364, "Dilated cardiomyopathy ": 8.500444015601486, "Disease progression ": 7.698146774538394, "Dry skin ": 2.423594277497117, "Ejection fraction abnormal ": 12.262746213510905, "Ejection fraction decreased ": 86.36710166560017, "Febrile neutropenia ": 7.358378751322185, "Granulocyte count decreased ": 8.519913535980328, "Granulocytopenia ": 4.195554295358837, "HER2 positive breast cancer ": 100.46124334043576, "Hair colour changes ": 5.160034083773915, "Hair texture abnormal ": 9.952475578000737, "Hepatic function abnormal ": 2.030584157575595, "Hypersensitivity ": 2.044519844185695, "Hypertransaminasaemia ": 4.0855247386006255, "Ill-defined disorder ": 2.488874156373861, "Infusion related reaction ": 13.78088985863785, "Intentional product use issue ": 2.451642646884129, "Interstitial lung disease ": 6.659204131341141, "Lacrimation increased ": 2.6089338111470703, "Left ventricular dysfunction ": 15.078983352772816, "Leukopenia ": 2.0095230153048336, "Lung infiltration ": 3.122007351119766, "Lymphoedema ": 7.097262975626716, "Lymphoma ": 2.0960493033904832, "Madarosis ": 20.146285544475266, "Mass ": 2.654234136363378, "Metastases to bone ": 8.710863335773325, "Metastases to central nervous system ": 29.56260290571279, "Metastases to liver ": 7.591623934907175, "Metastases to lung ": 7.084990561471039, "Metastases to lymph nodes ": 7.10243917847237, "Metastasis ": 4.809965350308519, "Metastatic neoplasm ": 14.712173388250616, "Mitral valve incompetence ": 5.941691618514279, "Mucosal inflammation ": 8.114971067489925, "Myelosuppression ": 18.18597533459476, "Nail disorder ": 11.556539537691254, "Neoplasm ": 3.380014602364869, "Neuropathy peripheral ": 6.444814337837478, "Neutropenia ": 3.314175636219788, "Neutrophil count decreased ": 8.998534002119026, "No adverse event ": 2.3075808163853666, "Oligohydramnios ": 7.314465437185395, "Onychoclasis ": 9.586571978680464, "Oxygen saturation decreased ": 2.0195810231110745, "Palmar-plantar erythrodysaesthesia syndrome ": 2.8090431608328625, "Paronychia ": 8.513438932237628, "Pericardial effusion ": 3.5529399031931543, "Peripheral sensory neuropathy ": 3.854672781068957, "Platelet count decreased ": 4.771354433435741, "Pleural effusion ": 3.846065370159309, "Pneumocystis jirovecii pneumonia ": 2.172956973179268, "Pneumonitis ": 4.936085658016009, "Polyneuropathy ": 3.995612132084032, "Pregnancy ": 4.709416242581648, "Pulmonary fibrosis ": 2.1951484717100342, "Recurrent cancer ": 12.4395004226943, "Red blood cell count decreased ": 2.6331414665676496, "Skin fissures ": 3.87366899550238, "Stomatitis ": 2.890219508815301, "Temperature intolerance ": 5.6878798243618585, "Therapy partial responder ": 3.295312851944208, "Tumour lysis syndrome ": 4.192336474724116, "White blood cell count decreased ": 6.7191966983459785}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/529.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/529.json
index df1cd92c37e..25967393af4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/529.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/529.json
@@ -1 +1 @@
-{"Diarrhoea ": 2.778330915051903, "Neutropenia ": 10.413710447962572, "Thrombocytopenia ": 5.796019187059625}
\ No newline at end of file
+{"Anti factor VIII antibody positive": 2526.0794837119424, "Factor VIII inhibition": 2562.360690650658, "Haemarthrosis": 316.6600559403955}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/53.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/53.json
index 8f72d19c99d..ccb604f046a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/53.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/53.json
@@ -1 +1 @@
-{"Drug ineffective ": 3.599878987336271, "Product use in unapproved indication ": 21.375050404928874}
\ No newline at end of file
+{"Abdominal discomfort": 2.092793478696998, "Abortion induced": 7.836776543866765, "Adjustment disorder": 818.1305267323465, "Affect lability": 133.0812008876443, "Amnesia": 7.829551754069855, "Angina pectoris": 20.724897050834283, "Anxiety": 6.050632562910637, "Aphasia": 42.99519541246691, "Arterial occlusive disease": 138.53229877082163, "Arthritis": 14.818245905344613, "Atrioventricular block": 4.497343274366538, "Blood potassium increased": 4.4419691280030245, "Blood pressure inadequately controlled": 75.99099588576873, "Blood pressure increased": 6.840133936477819, "Cardiac failure": 3.0790221933820163, "Cardiac failure chronic": 12.397215735798724, "Cardiac septal defect": 66.84979291840278, "Carotid artery thrombosis": 1760.099041594252, "Cataract": 21.66201905894724, "Cerebrovascular accident": 10.38804645174454, "Chest discomfort": 5.8874601522147785, "Cognitive disorder": 11.167348743479756, "Concomitant disease progression": 66.92154223453393, "Confusional state": 8.276510215654808, "Congenital cardiovascular anomaly": 34.60351121267122, "Conjoined twins": 920.3623044209572, "Contusion": 6.227433697802036, "Coordination abnormal": 108.306727598702, "Cough": 3.1588644731960427, "Cystitis": 45.12453802384778, "Depressed mood": 8.56427270464838, "Diabetes mellitus inadequate control": 16.349722221540553, "Dysarthria": 33.22336776202583, "Dysphagia": 17.394934990763517, "Eating disorder": 92.73527678299102, "Electrolyte imbalance": 4.595658487868896, "Exercise tolerance decreased": 41.09016130330909, "Fall": 7.168638692629903, "Foetal exposure during pregnancy": 2.613055227838435, "Gangrene": 201.48327063640147, "Gastrointestinal disorder": 11.264793254731003, "Haemoglobin abnormal": 19.845709258691716, "Heart disease congenital": 9.771826857909712, "Hemiparesis": 73.54799271646382, "Hemiplegia": 121.997391676684, "Hyperaldosteronism": 202.6854615293846, "Hyperkalaemia": 3.846664079087128, "Hypertension": 3.5441547102119166, "Hypertensive crisis": 3.102002037349749, "Immune thrombocytopenia": 4.956591359390759, "Impaired work ability": 9.104653379261858, "Low birth weight baby": 3.7021105120111297, "Medication error": 6.188929594928199, "Mobility decreased": 9.265639333137612, "Motor dysfunction": 50.08489984154525, "Mouth haemorrhage": 10.808226262775586, "Multiple drug therapy": 163.32787132305566, "Muscle spasticity": 52.51727280982763, "Muscular weakness": 4.496993352990492, "Neurologic neglect syndrome": 822.8640356071669, "Oedema peripheral": 6.304420880612164, "Personality disorder": 173.4037778316689, "Sensory loss": 41.62942490620197, "Skin haemorrhage": 11.37354959952812, "Treatment noncompliance": 11.46758455041657, "Truncus arteriosus persistent": 426.2261213153745, "Vascular calcification": 234.6591583672312, "Ventricular septal defect": 7.086557109082546, "Ventricular tachycardia": 3.893809904299432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/530.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/530.json
index 87315fd9c1c..44be3b4fbf8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/530.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/530.json
@@ -1 +1 @@
-{"Body temperature increased ": 10.32958251899102, "Crying ": 92.71839472572414, "Decreased appetite ": 4.664113215875697, "Diarrhoea ": 2.006424343382077, "Hypotonic-hyporesponsive episode ": 271.509093342318, "Irritability ": 15.450146402249551, "Pyrexia ": 3.333429449267536, "Restlessness ": 15.067242250313717}
\ No newline at end of file
+{"Bradycardia": 16.132467294375136, "Bronchiolitis": 88.93939424432632, "Drug titration error": 2301.0846467385527, "Hypoglycaemia": 23.190356217579197, "Hypoglycaemic seizure": 309.97633300646106, "Hypotension": 2.2237614150822407, "Irritability": 11.936315204990535, "Off label use": 13.712581288477454, "Product administered to patient of inappropriate age": 229.77071380582444, "Product use issue": 19.676594100050394, "Sleep disorder": 21.843204118528053, "Somnolence": 2.54124198905602}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/531.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/531.json
index 3f2a183e86b..7a7b9a691a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/531.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/531.json
@@ -1 +1 @@
-{"Allergy to metals ": 610.2763127030163, "Apathy ": 8.161867337607076, "Child maltreatment syndrome ": 3416.1109959636137, "Crying ": 27.844182582473746, "Cyanosis ": 11.405362204928052, "Erythema ": 2.038549033654611, "Febrile convulsion ": 53.758907140888994, "Hyperpyrexia ": 169.63819112844877, "Hypotonia ": 14.955513028298991, "Hypotonic-hyporesponsive episode ": 100.34455324278557, "Irritability ": 7.458123195875359, "Neurodermatitis ": 101.14428493815488, "Opisthotonus ": 109.67758439435184, "Pallor ": 13.751735599676266, "Pyrexia ": 4.872707947582511, "Reaction to excipient ": 158.01937603946033, "Restlessness ": 14.785980249796228, "Scratch ": 248.62180176241336, "Screaming ": 68.83905875963742, "Skin wound ": 634.1460256189082, "Sleep disorder ": 5.602653087644858, "Sudden infant death syndrome ": 234.6567004896544, "Unresponsive to stimuli ": 6.37297324703269, "Urticaria ": 4.1897069741485575, "Vaccination site discolouration ": 260.6918853920437, "Vaccination site eczema ": 551.143739752107, "Vaccination site erythema ": 14.862515432037831, "Vaccination site granuloma ": 1511.2063477437218, "Vaccination site hypertrichosis ": 1036.1351899356696, "Vaccination site hypertrophy ": 1777.208906920939, "Vaccination site irritation ": 229.8750314901758, "Vaccination site pruritus ": 35.2598687676903, "Vaccination site rash ": 19.683592590916295, "Vaccination site swelling ": 7.553123867549315}
\ No newline at end of file
+{"Activated partial thromboplastin time prolonged": 72.05148900873449, "Acute myocardial infarction": 3.300221122539162, "Blood urine present": 12.771701943754934, "Cerebral haemorrhage": 3.915056627534883, "Cerebral infarction": 4.473312702598258, "Contusion": 5.318568596240191, "Drug level decreased": 11.93836889004657, "Drug level increased": 4.259139563805238, "Drug specific antibody present": 158.56430117260803, "Epistaxis": 4.401989015957592, "Fall": 6.730657752292939, "Gastric haemorrhage": 13.331516630039411, "Gastrointestinal haemorrhage": 6.294670412179276, "Gingival bleeding": 13.547923342503749, "Haemarthrosis": 398.94422635045646, "Haematoma": 10.673501489683895, "Haematoma muscle": 32.78587640673578, "Haematuria": 5.609204308743358, "Haemorrhage": 77.88142669776944, "Haemorrhage intracranial": 6.886895254851355, "Head injury": 32.61547141284012, "Injection site reaction": 2.481843720567228, "Injury": 8.665604238362501, "Intentional product use issue": 3.748389255691916, "Joint injury": 13.858352433988214, "Joint swelling": 2.0475177380630503, "Ligament sprain": 20.438175479098213, "Limb injury": 8.90856941147081, "Mouth haemorrhage": 45.31209499041631, "Muscle haemorrhage": 368.8851761018944, "Nephritis": 22.588099575935384, "Nephrolithiasis": 4.423643886857319, "No adverse event": 4.966154478585073, "Post procedural haemorrhage": 26.97633434903145, "Procedural haemorrhage": 33.57126784887463, "Renal haemorrhage": 44.88643496986472, "Road traffic accident": 3.418749076493913, "Skin laceration": 15.78821221592371, "Spontaneous haemorrhage": 180.42468064031465, "Subdural haematoma": 5.7370897854496885, "Therapeutic response decreased": 3.0126749314159555, "Traumatic haemorrhage": 261.1155952554108, "Underdose": 4.63283956594904}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/532.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/532.json
index 019ce270081..cc27b1a1586 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/532.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/532.json
@@ -1 +1 @@
-{"Abscess ": 2.528086955448713, "Administration site erythema ": 8.922399275127102, "Administration site reaction ": 19.77842550969847, "Adverse reaction ": 2.6565860649088613, "Atypical pneumonia ": 10.291454376890655, "Bacterial infection ": 3.2044479059391437, "Blood immunoglobulin G decreased ": 36.27031361807778, "Bronchiectasis ": 3.532536809394802, "Bronchitis ": 7.538495760177081, "Cardiac operation ": 4.95932656514605, "Catheterisation cardiac ": 5.835808709415831, "Cellulitis ": 5.166008982974264, "Chemotherapy ": 9.502185639318814, "Cholecystectomy ": 6.668405516410621, "Chronic inflammatory demyelinating polyradiculoneuropathy ": 58.07516676876715, "Chronic obstructive pulmonary disease ": 2.6881019632280445, "Clostridium difficile infection ": 3.743072382185313, "Cystitis ": 2.402208281316053, "Diverticulitis ": 3.3385121933344437, "Ear infection ": 9.069595599427752, "Escherichia infection ": 5.26026880475716, "Eye infection ": 5.559984873022812, "Fungal infection ": 2.010865237939614, "Gastric infection ": 13.862621940632469, "Gastroenteritis viral ": 5.274418581368087, "Hepatitis B ": 9.958667306868112, "Hepatitis B core antibody positive ": 38.189111717167016, "Hepatitis B surface antibody positive ": 51.77164990739778, "Hepatitis B virus test positive ": 50.52758032331322, "Hospitalisation ": 3.655486723706253, "Ill-defined disorder ": 3.579308857100964, "Immunoglobulins decreased ": 33.738866848222536, "Incorrect drug administration rate ": 7.367623049050164, "Infection ": 4.452126040231827, "Infusion site abscess ": 446.1142005373127, "Infusion site bruising ": 442.32685632151816, "Infusion site cellulitis ": 240.237802580342, "Infusion site discharge ": 309.9111977950611, "Infusion site discolouration ": 109.28780419841054, "Infusion site erythema ": 219.9994685294065, "Infusion site extravasation ": 15.37860710175936, "Infusion site haemorrhage ": 109.82311609014116, "Infusion site induration ": 163.63267015910438, "Infusion site infection ": 116.33437722823396, "Infusion site inflammation ": 68.76974051101088, "Infusion site irritation ": 108.78686453360515, "Infusion site mass ": 170.6550307713755, "Infusion site nodule ": 992.904496928134, "Infusion site oedema ": 49.51602992480217, "Infusion site pain ": 116.9425723282699, "Infusion site pruritus ": 261.2755060893157, "Infusion site rash ": 137.91807049067268, "Infusion site reaction ": 41.18562855320863, "Infusion site scab ": 506.3751079093613, "Infusion site swelling ": 264.04880842210986, "Infusion site ulcer ": 397.2090663079029, "Infusion site urticaria ": 296.54364937158067, "Infusion site vesicles ": 126.37602513076978, "Infusion site warmth ": 263.4540219891296, "Injection site bruising ": 2.144302958553334, "Injection site discharge ": 22.38434433456228, "Injection site discomfort ": 3.222536202910875, "Injection site erythema ": 3.5978678448564683, "Injection site induration ": 5.37953995258993, "Injection site infection ": 11.669536280759608, "Injection site irritation ": 12.623836290080211, "Injection site mass ": 5.087958634138352, "Injection site necrosis ": 13.817646409161682, "Injection site nodule ": 7.399300738917742, "Injection site oedema ": 2.163407103728765, "Injection site pruritus ": 4.280869680900624, "Injection site rash ": 4.797894981870561, "Injection site swelling ": 2.43063618930381, "Injection site ulcer ": 19.73151133587743, "Injection site urticaria ": 7.536768900084261, "Insurance issue ": 30.638194974535697, "Intestinal obstruction ": 2.3160482482814104, "Kidney infection ": 10.667244022158858, "Knee operation ": 5.8288378240947525, "Laryngitis ": 2.7231604842193677, "Limb operation ": 7.896683055121838, "Liquid product physical issue ": 4.500303814138518, "Lower respiratory tract infection ": 2.6201207671526983, "Lymphoma ": 2.256366044162881, "Meningitis ": 4.4043238105405536, "Meningitis aseptic ": 42.02005390010969, "Migraine ": 2.5997491242597524, "Nephrolithiasis ": 4.9939794894243255, "No adverse event ": 47.4727639798165, "Osteomyelitis ": 3.664592450902416, "Pharyngeal swelling ": 2.3012153729172047, "Pharyngitis streptococcal ": 7.556099067877654, "Pneumonia ": 6.286132259623117, "Product dose omission issue ": 2.6656307343340377, "Product supply issue ": 6.8775119565018885, "Product use complaint ": 3.3341869728334395, "Productive cough ": 2.8428069051672966, "Pseudomonas infection ": 5.671568869839827, "Recalled product administered ": 34.97980577250664, "Respiratory syncytial virus infection ": 4.202987451343903, "Respiratory tract congestion ": 2.99776304786257, "Respiratory tract infection ": 21.701726261615917, "Sinus congestion ": 3.3844417600672063, "Sinus disorder ": 5.2703287194656205, "Sinus operation ": 58.83111044456636, "Sinusitis ": 15.21091654878596, "Skin infection ": 7.779624734117752, "Skin mass ": 2.5646149742877262, "Skin reaction ": 2.4085911803181643, "Spinal operation ": 6.173474807894262, "Sputum discoloured ": 4.471242491455896, "Staphylococcal infection ": 9.890603931125645, "Stent placement ": 5.323996691807925, "Streptococcal infection ": 9.918279237222045, "Surgery ": 4.645676131964215, "Suspected transmission of an infectious agent via product ": 90.52469828045076, "Therapy cessation ": 9.459249774535277, "Therapy change ": 11.00637861506064, "Therapy interrupted ": 20.138043522854318, "Throat tightness ": 2.7145609839018694, "Thrombosis ": 2.854015766676838, "Tooth abscess ": 6.940010287625394, "Tooth infection ": 4.314104281288132, "Transient ischaemic attack ": 2.064851381804484, "Unevaluable event ": 6.289373205270835, "Upper respiratory tract infection ": 8.368358491661287, "Urinary tract infection ": 3.164035086404197, "Urine output decreased ": 6.549645339925149, "Viral infection ": 4.502516505989992, "Weight fluctuation ": 10.59553145379274, "Wound infection ": 3.2654064625317405}
\ No newline at end of file
+{"Acquired aminoaciduria": 2329.632271930392, "Alanine aminotransferase increased": 6.913328566193478, "Aminoaciduria": 731.2622665216284, "Ascites": 2.3581492124856798, "Aspartate aminotransferase increased": 2.7141186718930794, "Back pain": 4.143619523804344, "Beta 2 microglobulin increased": 289.51718883776385, "Beta 2 microglobulin urine increased": 323.52143498466376, "Blood alkaline phosphatase increased": 28.16834807378762, "Blood bilirubin increased": 3.3453950080861063, "Blood creatine phosphokinase MB increased": 37.52840267058623, "Blood creatine phosphokinase increased": 2.592709736848435, "Blood creatinine increased": 8.54923707554949, "Blood phosphorus decreased": 391.6936320071961, "Blood potassium decreased": 4.202519375968437, "Blood uric acid decreased": 225.6894386343257, "Bone metabolism disorder": 190.04427165810185, "Bone pain": 13.581229409506877, "Creatinine renal clearance decreased": 21.44767353389637, "Disease recurrence": 2.2589199340022503, "Drug ineffective": 2.209758904702247, "Drug resistance": 48.16925443337597, "Drug tolerance": 15.61960145484399, "Fanconi syndrome": 307.7260100795215, "Fanconi syndrome acquired": 486.0392539776995, "Femoral neck fracture": 48.62599775848373, "Femur fracture": 5.182428961977306, "Foot fracture": 5.8403118744172975, "Fracture": 10.55615778216707, "Gait disturbance": 3.527266395187353, "Genotype drug resistance test positive": 38.522496795404365, "Glomerular filtration rate decreased": 9.909123720359222, "Glucose urine present": 100.6072620648826, "Glycosuria": 47.59055984878525, "Hepatic cancer": 18.086266146471115, "Hepatic cirrhosis": 8.428477113072669, "Hepatic failure": 3.7644806714094976, "Hepatic steatosis": 4.225463456311646, "Hepatitis": 3.6994466954406735, "Hepatitis B": 40.75201156813115, "Hepatitis B DNA assay positive": 191.44061970449027, "Hepatitis B DNA increased": 338.42826030452915, "Hepatitis B reactivation": 44.65817401307872, "Hepatocellular carcinoma": 12.485046651037486, "Hyperphosphatasaemia": 925.0294550685296, "Hypophosphataemia": 389.2838046527665, "Hypophosphataemic osteomalacia": 1033.3298314677031, "Hypouricaemia": 1112.684669710175, "Jaundice": 3.5537000308467173, "Liver disorder": 2.052152721024981, "Metabolic acidosis": 9.569751333342657, "Movement disorder": 2.1368420258205894, "Multiple fractures": 3.6000743399115893, "Muscular weakness": 2.943874475443774, "Musculoskeletal chest pain": 6.291496500752625, "Nephropathy": 2.702581694389534, "Nephropathy toxic": 6.925310611766496, "Osteomalacia": 645.4999120606287, "Osteoporosis": 7.13236119592556, "Pathogen resistance": 7.553551912943149, "Pathological fracture": 49.06039601632977, "Product complaint": 3.57557203930012, "Protein urine present": 28.01542513836638, "Proteinuria": 13.164315772820816, "Renal disorder": 9.787036436220111, "Renal failure": 2.164966829025518, "Renal function test abnormal": 23.30656627631284, "Renal glycosuria": 1245.135526670312, "Renal impairment": 15.278515022120454, "Renal tubular acidosis": 57.90662626641055, "Renal tubular disorder": 98.07129314915124, "Renal tubular dysfunction": 103.9915162946266, "Rib fracture": 16.381379774631004, "Spinal compression fracture": 9.72577058560791, "Therapeutic response decreased": 8.233763100962967, "Therapy non-responder": 2.7148491540248103, "Tibia fracture": 18.285661805768235, "Transaminases increased": 2.0753699087649125, "Tubulointerstitial nephritis": 6.974678317951045, "Urine calcium increased": 170.04222116763145, "Urine phosphorus increased": 1118.0887978753017, "Viral infection": 3.203725538308833, "Viral load increased": 73.73402075593185, "Viral mutation identified": 52.85393391499872, "Virologic failure": 12.064851630748649}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/533.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/533.json
index 5babef414de..b57bf48a3f3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/533.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/533.json
@@ -1 +1 @@
-{"Abscess limb ": 2.423970573245167, "Accident ": 5.134296090486663, "Accident at work ": 5.531772209135802, "Accidental underdose ": 57.48463044537778, "Addison's disease ": 3.133679690100156, "Amputation ": 10.009123883071144, "Aneurysm ": 3.5631461382820944, "Angiopathy ": 2.959117705276686, "Animal bite ": 5.502912499872712, "Ankle fracture ": 3.3332642325989776, "Anti-insulin antibody ": 43.08463888836064, "Anti-insulin antibody increased ": 45.96755765258344, "Anti-insulin antibody positive ": 44.50766885741264, "Apgar score low ": 2.0033998277186664, "Arterial disorder ": 2.588967014562717, "Arterial occlusive disease ": 6.249310017616688, "Arterial stenosis ": 4.0712360669832846, "Arteriovenous malformation ": 8.959727133086355, "Arthritis ": 3.2927484422081994, "Arthropod bite ": 2.278627136169689, "Astigmatism ": 2.738801515105753, "Autonomic neuropathy ": 3.8413768636772736, "Back disorder ": 3.3259737918441337, "Back injury ": 2.0551448998794077, "Barrett's oesophagus ": 3.39694587919068, "Blindness ": 12.932367505458654, "Blindness transient ": 2.1680635879104875, "Blindness unilateral ": 11.997009446823066, "Blood glucose abnormal ": 41.51751871314652, "Blood glucose decreased ": 61.93563622436351, "Blood glucose fluctuation ": 30.054909609116542, "Blood glucose increased ": 43.88325485232816, "Blood insulin increased ": 23.709868522952835, "Blood ketone body ": 27.731487781647367, "Blood ketone body increased ": 16.000397660333935, "Blood ketone body present ": 3.643675920057981, "Blood pressure abnormal ": 2.28910518880132, "Blood zinc decreased ": 27.84800049505192, "Brain injury ": 3.595874994391312, "Brain neoplasm ": 3.75165265767888, "Brain neoplasm benign ": 13.16984413643266, "Cardiac disorder ": 4.054980977755793, "Cardiac failure congestive ": 3.449788401241661, "Cardiac valve disease ": 3.116608973153407, "Carotid artery occlusion ": 5.610036303401736, "Carpal tunnel syndrome ": 4.593000472920966, "Cataract ": 9.839782553755816, "Cerebral disorder ": 3.457213742481981, "Cerebrovascular accident ": 4.379197878243405, "Cervical vertebral fracture ": 3.620615356046761, "Chronic obstructive pulmonary disease ": 2.071451752506519, "Colon cancer ": 2.863102979249037, "Coma ": 2.470026658115763, "Concussion ": 2.6416962926804564, "Coronary artery bypass ": 2.5464972087956617, "Coronary artery disease ": 2.65238476180101, "Coronary artery occlusion ": 3.982714921896443, "Cutaneous amyloidosis ": 55.943347784993016, "Dawn phenomenon ": 51.44004911211495, "Deafness unilateral ": 2.97294524011579, "Dementia ": 6.70026152103368, "Dementia Alzheimer's type ": 9.090033673300798, "Diabetes mellitus inadequate control ": 14.30079560171121, "Diabetic blindness ": 85.2915186896516, "Diabetic coma ": 28.60281995299111, "Diabetic complication ": 35.37550111586806, "Diabetic eye disease ": 32.44745844754265, "Diabetic foot ": 23.94745638444631, "Diabetic foot infection ": 12.773037820135862, "Diabetic gangrene ": 21.28346852925818, "Diabetic gastroparesis ": 21.033150799084908, "Diabetic hyperglycaemic coma ": 22.078109391635746, "Diabetic ketoacidosis ": 19.34999277705633, "Diabetic ketoacidotic hyperglycaemic coma ": 18.37649268819292, "Diabetic ketosis ": 8.862039809632307, "Diabetic metabolic decompensation ": 3.312638011997777, "Diabetic nephropathy ": 10.163761874487356, "Diabetic neuropathy ": 18.282970033246286, "Diabetic retinopathy ": 51.53453526429638, "Drug hypersensitivity ": 2.281798921261733, "Drug ineffective ": 2.281226949699549, "Expired product administered ": 8.425817092861745, "Exposure via breast milk ": 2.807930018753666, "Extra dose administered ": 3.215002925208073, "Eye disorder ": 5.44849776292134, "Eye haemorrhage ": 17.461212754937904, "Eye injury ": 3.809969923747053, "Eye laser surgery ": 12.728311454621153, "Eye operation ": 2.9594184603574747, "Face injury ": 2.2148289353621884, "Fall ": 3.032765396243481, "Fat tissue increased ": 4.6365249166886455, "Feeding disorder ": 2.239621408551056, "Feeling abnormal ": 2.0173551651203496, "Femur fracture ": 2.505115008597845, "Fine motor skill dysfunction ": 2.6415203236234994, "Food poisoning ": 3.091107502744825, "Foot fracture ": 2.2030633807493145, "Gait inability ": 2.161026674735167, "Gangrene ": 9.007006637029564, "Gastroenteritis viral ": 2.176071078518933, "Gestational hypertension ": 3.919646916994599, "Glaucoma ": 7.70953006500159, "Glucose-6-phosphate dehydrogenase deficiency ": 95.23771580825802, "Glycosylated haemoglobin abnormal ": 9.749623360669291, "Glycosylated haemoglobin decreased ": 6.058077322015009, "Glycosylated haemoglobin increased ": 30.898597816481185, "Head injury ": 3.5914285189349053, "Hepatitis A ": 16.22729603318962, "Hernia ": 2.6288768182658497, "Herpes simplex ": 3.045355627835913, "Hip fracture ": 3.4040746331742224, "Humerus fracture ": 2.309384445238891, "Hunger ": 5.660684758757535, "Hypercoagulation ": 2.9039535676329997, "Hyperglycaemia ": 12.63845637842158, "Hyperglycaemic unconsciousness ": 39.040399199190375, "Hyperinsulinaemic hypoglycaemia ": 60.11258375732549, "Hyperkeratosis ": 2.3334183386466307, "Hypermetropia ": 2.9411069982300866, "Hypoacusis ": 4.181570700584396, "Hypoglycaemia ": 23.835807177441875, "Hypoglycaemia neonatal ": 7.402147314719574, "Hypoglycaemia unawareness ": 81.60970471558056, "Hypoglycaemic coma ": 26.64737693109664, "Hypoglycaemic encephalopathy ": 9.389388590552498, "Hypoglycaemic seizure ": 38.83323533030466, "Hypoglycaemic unconsciousness ": 38.73787878089617, "Hypophagia ": 2.138261525220665, "Illness ": 2.417163991948005, "Impaired gastric emptying ": 6.906755723416346, "Impaired healing ": 2.2494946416641057, "Incoherent ": 2.6164135954225056, "Incorrect dosage administered ": 5.079578110604515, "Incorrect dose administered ": 17.720115081805087, "Incorrect product administration duration ": 9.035979882442422, "Incorrect product dosage form administered ": 7.7615260384409615, "Incorrect product formulation administered ": 25.88890783753506, "Increased insulin requirement ": 14.366962285987526, "Infarction ": 2.0355116500414003, "Infusion site infection ": 6.38068917777827, "Injection site atrophy ": 5.540786619491613, "Injection site bruising ": 7.220277265172006, "Injection site haemorrhage ": 5.516411457802968, "Injection site hypersensitivity ": 3.574980948566243, "Injection site infection ": 2.6274436113433217, "Injection site injury ": 5.367992592604903, "Injection site irritation ": 2.584536848938182, "Injection site mass ": 5.3933389154404345, "Injection site scar ": 13.947291957017791, "Injection site urticaria ": 4.409697891694683, "Injury associated with device ": 14.483456703818993, "Insulin C-peptide decreased ": 30.74465337518028, "Insulin resistance ": 57.62930720467428, "Insulin resistant diabetes ": 78.20262167219502, "Intercepted product dispensing error ": 52.15020285167839, "Intercepted product selection error ": 104.3391302207189, "Intervertebral disc degeneration ": 2.2486722254043072, "Intervertebral disc protrusion ": 2.97393137794468, "Intracranial aneurysm ": 2.02433350206806, "Jaundice neonatal ": 3.385428116203092, "Joint injury ": 3.1752238367787284, "Ketoacidosis ": 13.481705582495389, "Ketonuria ": 5.066176920903752, "Ketosis ": 10.904758441045582, "Large for dates baby ": 18.649890323998875, "Leg amputation ": 5.516518080632216, "Ligament disorder ": 8.466224930517543, "Ligament rupture ": 2.0414072396363627, "Limb deformity ": 2.2501366278233483, "Limb injury ": 6.068354649300743, "Lip injury ": 3.503806135454594, "Lipids increased ": 2.873277170397168, "Lipoatrophy ": 7.627500257782525, "Lipohypertrophy ": 5.723343559366875, "Lipoma ": 2.9311809518849734, "Localised infection ": 7.845262910914044, "Loss of consciousness ": 3.46907131798296, "Lower limb fracture ": 4.079368559392479, "Macular degeneration ": 6.873135908429041, "Macular oedema ": 4.321691850946753, "Maculopathy ": 2.8347756652507394, "Malabsorption from injection site ": 48.65424171960977, "Malnutrition ": 10.113088864055069, "Medication error ": 3.285766161547184, "Memory impairment ": 4.055099621342925, "Meniscus injury ": 2.4132122228082467, "Microalbuminuria ": 18.042749946604467, "Multi-organ disorder ": 49.34177021652342, "Musculoskeletal disorder ": 2.0102312679837926, "Myocardial infarction ": 3.3307101858068573, "Myopia ": 3.4181106878652328, "Neck injury ": 5.253712110222016, "Neoplasm malignant ": 2.701503050793737, "Neovascular age-related macular degeneration ": 3.593824546640325, "Nerve compression ": 3.869279632810292, "Nerve injury ": 3.1429455018269894, "Neuropathic arthropathy ": 41.50460065641253, "Neuropathy peripheral ": 3.867009751120541, "Nonspecific reaction ": 3.319821636926553, "Nosocomial infection ": 2.330788457325879, "Osteomyelitis ": 6.063820391767351, "Overweight ": 4.3363732384206175, "Pancreatic abscess ": 17.145873204941108, "Pancreatic disorder ": 11.37197562329227, "Pancreatic failure ": 7.267595990314433, "Parkinson's disease ": 3.8719616118628535, "Patella fracture ": 2.8024408704587014, "Pelvic fracture ": 2.977328031505329, "Pericardial effusion ": 3.070549191432192, "Peripheral artery occlusion ": 3.456858238818632, "Peripheral vascular disorder ": 2.024454419421392, "Pollakiuria ": 2.106559315281079, "Poor peripheral circulation ": 5.702083194997125, "Poor quality product administered ": 3.0793215704199075, "Post procedural complication ": 4.741386534633255, "Post procedural infection ": 3.6401411605545406, "Postoperative wound infection ": 3.2183765536974045, "Postprandial hypoglycaemia ": 16.0670790429748, "Pre-eclampsia ": 4.591116386320009, "Premature baby ": 2.491856840522042, "Premature labour ": 2.218312926312457, "Presbyopia ": 6.14435445555031, "Product administration error ": 2.087105649241942, "Product dispensing error ": 6.752393443766357, "Product dose omission issue ": 6.184390448022632, "Product name confusion ": 10.606230974206628, "Product storage error ": 14.61816584765003, "Product tampering ": 19.2821272710958, "Prostatic disorder ": 2.230458706492033, "Pulmonary oedema ": 2.6133288243702224, "Rectal cancer ": 2.052474809502654, "Renal disorder ": 5.050404347458047, "Renal transplant ": 4.1229021445149785, "Retinal detachment ": 8.587443620426185, "Retinal disorder ": 10.52188030825366, "Retinal haemorrhage ": 5.029611148245983, "Retinal injury ": 9.023996745198552, "Retinal tear ": 5.77192100095002, "Retinopathy ": 14.154944278469465, "Rhinitis allergic ": 2.931694052766853, "Rib fracture ": 2.152843009152915, "Road traffic accident ": 7.132725347175257, "Rotator cuff syndrome ": 2.913511354310729, "Scar ": 2.944494538549733, "Shock hypoglycaemic ": 31.95233324724992, "Shoulder fracture ": 5.059821612431992, "Skin ulcer ": 2.8211535741436213, "Sleep apnoea syndrome ": 2.531347065786174, "Snoring ": 7.89045088823018, "Sopor ": 7.000230499893152, "Spinal column injury ": 3.457693431630662, "Spinal disorder ": 2.1759357036878173, "Spinal stenosis ": 3.14089492460239, "Staphylococcal infection ": 2.305646006901139, "Stress ": 4.736833351745925, "Suspected transmission of an infectious agent via product ": 8.472359952967983, "Therapeutic product effect delayed ": 6.786308042721581, "Therapeutic product effect increased ": 2.337830126489203, "Therapeutic response delayed ": 9.70174829135984, "Thirst ": 2.5035340959028383, "Throat cancer ": 2.484660999749372, "Thyroid disorder ": 6.992386315099293, "Toe amputation ": 7.326867014125879, "Trigger finger ": 15.33770460523214, "Underdose ": 5.2565795328222205, "Upper limb fracture ": 2.146620976444429, "Urine ketone body present ": 10.572806907627688, "Vascular graft ": 4.523296790439978, "Vascular occlusion ": 8.354291217511173, "Vein disorder ": 2.242360424173966, "Venous occlusion ": 2.2699825726523666, "Visual acuity reduced ": 2.261790204874336, "Visual impairment ": 6.828254123474561, "Vitreous haemorrhage ": 3.656538496811119, "Weight abnormal ": 4.975809372949913, "Weight decreased ": 2.250498445144471, "Weight increased ": 2.6773538754108523, "Wound complication ": 2.2373073071702367, "Wound infection ": 3.0540353567091656, "Wrong patient received product ": 7.187099223907235, "Wrong product administered ": 26.60076480993916, "Wrong technique in product usage process ": 3.7549919374923535}
\ No newline at end of file
+{"Abdominal pain": 3.9519428340301377, "Drug interaction": 6.361007207976812, "Overdose": 4.36787360081528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/534.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/534.json
index 8c324b25f63..d333198ed25 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/534.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/534.json
@@ -1 +1 @@
-{"Acute respiratory distress syndrome ": 2.9741158127953558, "Anaphylactic reaction ": 3.353627510609788, "Anaphylactoid reaction ": 9.077106355714786, "Anti factor VIII antibody positive ": 25.0229386184022, "Autoimmune haemolytic anaemia ": 14.266866150918984, "Bacteraemia ": 3.035931942615503, "Blood immunoglobulin G decreased ": 42.224203467572615, "Cardiogenic shock ": 2.352980698783336, "Coombs direct test positive ": 99.2069815265432, "Coronary artery aneurysm ": 125.62785344549354, "Cytomegalovirus infection ": 3.6848678315302, "Cytomegalovirus viraemia ": 7.990011173139972, "Deep vein thrombosis ": 2.500717685911884, "Dermatomyositis ": 10.006971464587856, "Disseminated intravascular coagulation ": 2.753045517383419, "Drug effective for unapproved indication ": 131.82840939780604, "Drug ineffective ": 5.722882319457908, "Drug ineffective for unapproved indication ": 107.69859318424828, "Drug resistance ": 5.150330505175726, "Dyshidrotic eczema ": 27.70027244521391, "Ear infection ": 3.5547058331081307, "Embolism ": 5.035406269515918, "Encephalitis ": 2.34549498838168, "Encephalitis autoimmune ": 11.298858648130482, "Epstein-Barr virus infection ": 4.6300469987518245, "Exposure during pregnancy ": 5.484184694915429, "Febrile nonhaemolytic transfusion reaction ": 82.12769403328932, "Foetal death ": 5.025831028697945, "Foetal exposure during pregnancy ": 4.790408728040396, "Foetal growth restriction ": 4.527883398263985, "Guillain-Barre syndrome ": 2.1335010644205, "Haemolysis ": 41.31251147247692, "Haemolytic anaemia ": 34.38749880849628, "Hemianopia homonymous ": 29.070209625223576, "Hepatitis B core antibody positive ": 43.11138032909053, "Hepatitis B surface antibody positive ": 55.46440502694127, "Hepatitis C ": 5.800916360538624, "Hypervolaemia ": 3.723911452673895, "Hypoxia ": 3.014060738086456, "Incorrect drug administration rate ": 18.415175313121495, "Infusion related reaction ": 2.6396432445734037, "Infusion site bruising ": 55.42009141406299, "Infusion site erythema ": 15.62718382716889, "Infusion site haemorrhage ": 69.15047975926672, "Infusion site pain ": 13.520994382603185, "Infusion site pruritus ": 24.884685448179056, "Intentional product use issue ": 9.49510192876428, "Ischaemic stroke ": 2.221641593992576, "Low birth weight baby ": 5.652287105920948, "Lupus-like syndrome ": 5.220276887316385, "Maternal exposure during pregnancy ": 3.2685919883204533, "Meningitis ": 3.0835514355770166, "Meningitis aseptic ": 102.35111657517828, "Misleading laboratory test result ": 442.7832890143675, "Multiple-drug resistance ": 11.08506671796665, "Myasthenia gravis ": 3.788017304848753, "Myositis ": 3.288561023640566, "Nephrotic syndrome ": 2.5153676693698848, "No adverse event ": 36.92807322490231, "Off label use ": 6.827542073059044, "Post procedural complication ": 5.889679632824693, "Posterior reversible encephalopathy syndrome ": 18.32105427120659, "Premature baby ": 5.091361208179787, "Premature delivery ": 2.3316607742190696, "Product use in unapproved indication ": 6.252972121762179, "Pulmonary embolism ": 2.998688500984221, "Respiratory distress ": 2.239396214724424, "Respiratory failure ": 2.1874171648282084, "Respiratory tract infection ": 2.5052957476922595, "Status epilepticus ": 3.756317920150319, "Stress cardiomyopathy ": 4.837802516709411, "Suspected counterfeit product ": 7.1070799062503545, "Tachypnoea ": 3.6129081772202407, "Therapeutic product effect incomplete ": 15.46923099115426, "Therapeutic response unexpected ": 11.606294007150304, "Therapy interrupted ": 3.219678766075916, "Therapy non-responder ": 13.877412348139584, "Therapy partial responder ": 14.333179066830636, "Toxic epidermal necrolysis ": 2.589178816128908, "Transfusion-related acute lung injury ": 196.10301491211683, "Transfusion-related circulatory overload ": 231.92152943682197}
\ No newline at end of file
+{"Acute myeloid leukaemia": 5.563235931985917, "Alopecia": 2.758326892691253, "Alopecia areata": 5.853647743634364, "Aortitis": 19.790133136971345, "Blood lactate dehydrogenase increased": 2.124833871112354, "Blood magnesium decreased": 4.846376007144799, "Breast cancer metastatic": 10.083868526044066, "Breast cancer recurrent": 30.195068805959075, "Cardiac disorder": 2.871957835538458, "Cardiac dysfunction": 74.86613243387622, "Cardiac failure": 14.30262324488131, "Cardiac failure acute": 7.144756622736439, "Cardiac failure congestive": 2.782753364936093, "Cardiomyopathy": 14.65855317058424, "Cardiotoxicity": 33.84908456206, "Dermatitis acneiform": 4.6161009540491165, "Diarrhoea": 3.973956475916241, "Dilated cardiomyopathy": 8.500444015601486, "Disease progression": 7.698146774538394, "Dry skin": 2.423594277497117, "Ejection fraction abnormal": 12.262746213510905, "Ejection fraction decreased": 86.36710166560017, "Febrile neutropenia": 7.358378751322185, "Granulocyte count decreased": 8.519913535980328, "Granulocytopenia": 4.194343384934607, "HER2 positive breast cancer": 100.46124334043576, "Hair colour changes": 5.160034083773915, "Hair texture abnormal": 9.952475578000737, "Hepatic function abnormal": 2.030584157575595, "Hypersensitivity": 2.044519844185695, "Hypertransaminasaemia": 4.0855247386006255, "Ill-defined disorder": 2.488874156373861, "Infusion related reaction": 13.78088985863785, "Intentional product use issue": 2.451642646884129, "Interstitial lung disease": 6.659204131341141, "Lacrimation increased": 2.6089338111470703, "Left ventricular dysfunction": 15.078983352772816, "Leukopenia": 2.009269440327385, "Lung infiltration": 3.122007351119766, "Lymphoedema": 7.097262975626716, "Lymphoma": 2.0960493033904832, "Madarosis": 20.146285544475266, "Mass": 2.654234136363378, "Metastases to bone": 8.710863335773325, "Metastases to central nervous system": 29.56260290571279, "Metastases to liver": 7.591623934907175, "Metastases to lung": 7.084990561471039, "Metastases to lymph nodes": 7.10243917847237, "Metastasis": 4.809965350308519, "Metastatic neoplasm": 14.712173388250616, "Mitral valve incompetence": 5.941691618514279, "Mucosal inflammation": 8.114971067489925, "Myelosuppression": 18.18597533459476, "Nail disorder": 11.556539537691254, "Neoplasm": 3.380014602364869, "Neuropathy peripheral": 6.444617904675028, "Neutropenia": 3.314032836589881, "Neutrophil count decreased": 8.998534002119026, "No adverse event": 2.3075808163853666, "Oligohydramnios": 7.314465437185395, "Onychoclasis": 9.586571978680464, "Oxygen saturation decreased": 2.0194728600436367, "Palmar-plantar erythrodysaesthesia syndrome": 2.8090431608328625, "Paronychia": 8.513438932237628, "Pericardial effusion": 3.5529399031931543, "Peripheral sensory neuropathy": 3.854672781068957, "Platelet count decreased": 4.771354433435741, "Pleural effusion": 3.845710468354262, "Pneumocystis jirovecii pneumonia": 2.172956973179268, "Pneumonitis": 4.936085658016009, "Polyneuropathy": 3.995612132084032, "Pregnancy": 4.709416242581648, "Pulmonary fibrosis": 2.1951484717100342, "Recurrent cancer": 12.4395004226943, "Red blood cell count decreased": 2.6331414665676496, "Skin fissures": 3.87366899550238, "Stomatitis": 2.890219508815301, "Temperature intolerance": 5.6878798243618585, "Therapy partial responder": 3.295312851944208, "Tumour lysis syndrome": 4.192336474724116, "White blood cell count decreased": 6.7191966983459785}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/535.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/535.json
index 6767b3a1471..13180751b34 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/535.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/535.json
@@ -1 +1 @@
-{"Abdominal abscess ": 4.089612509281598, "Abscess ": 6.908129252415575, "Acne ": 3.072057412892482, "Acute myocardial infarction ": 2.1083863218627625, "Adverse drug reaction ": 5.371628118115433, "Alanine aminotransferase abnormal ": 4.053585271267126, "Amputation ": 8.850896569739021, "Anal abscess ": 4.236894888333481, "Anal fissure ": 10.3175946154638, "Anal fistula ": 26.707534798010467, "Anal incontinence ": 3.516115873283779, "Animal bite ": 11.202214953071064, "Ankylosing spondylitis ": 11.47384731780143, "Anti-cyclic citrullinated peptide antibody ": 11.757513015983667, "Aphthous ulcer ": 2.023821222211253, "Arthritis ": 5.672546780484407, "Arthritis bacterial ": 6.066129117527454, "Arthritis infective ": 6.003757215095779, "Arthrodesis ": 8.826519533944474, "Arthropathy ": 2.630172971784552, "Arthropod bite ": 2.992104373090342, "Basal cell carcinoma ": 2.140917785821056, "Bladder transitional cell carcinoma ": 17.096688236784093, "Blood creatinine decreased ": 5.162526622884266, "Blood iron decreased ": 2.1522918297716678, "Bowel movement irregularity ": 6.146801776798209, "Bursitis ": 2.7826611785405087, "C-reactive protein abnormal ": 2.036057716825601, "C-reactive protein decreased ": 34.479027743948826, "C-reactive protein increased ": 2.807075524235502, "Candida infection ": 2.8393002074381046, "Cardiac pacemaker insertion ": 3.767177563296787, "Carpal tunnel syndrome ": 3.300463452940652, "Cataract ": 2.7187448663556104, "Cerebral venous sinus thrombosis ": 2.3589205436024123, "Cervical vertebral fracture ": 4.391541358766919, "Cholangitis sclerosing ": 11.96702018756216, "Cholecystectomy ": 2.6857466399380754, "Chronic cutaneous lupus erythematosus ": 21.63308931377145, "Clavicle fracture ": 5.155421744503673, "Clostridium difficile infection ": 2.920838904437826, "Coeliac disease ": 2.6707378290782176, "Colectomy ": 9.086762356189515, "Colitis ": 3.597647153516079, "Colitis ulcerative ": 11.859736030009048, "Colon cancer ": 2.2826380856405364, "Contraindicated product administered ": 2.3824559836587555, "Coronary artery occlusion ": 2.1742283244188614, "Crohn's disease ": 18.85909146792432, "Cystic fibrosis ": 8.24993517984446, "Cystitis ": 6.0555362823051455, "Dactylitis ": 9.77396142544771, "Defaecation urgency ": 11.902482273665877, "Demyelination ": 9.925071282928124, "Dermatitis exfoliative generalised ": 2.3024452415661725, "Diarrhoea haemorrhagic ": 5.571032566826793, "Disability ": 3.281130647581377, "Disease complication ": 4.249903297783173, "Diverticular perforation ": 9.91732426285414, "Diverticulitis ": 2.080586039258766, "Diverticulum ": 2.385131762101803, "Drug hypersensitivity ": 6.48584573273197, "Drug ineffective ": 4.082529080195643, "Drug intolerance ": 5.6008762153665925, "Drug level abnormal ": 39.534305112580185, "Drug level decreased ": 9.181185550406468, "Drug specific antibody ": 9.931142126017075, "Drug specific antibody present ": 19.19326179103208, "Dyschezia ": 10.088663416404128, "Dyslipidaemia ": 2.332446140839369, "Enthesopathy ": 3.5526512434833557, "Exostosis ": 2.8454322894402546, "Eye disorder ": 2.6357066813848906, "Eye infection ": 2.686660698082731, "Eye injury ": 10.811378478596708, "Faecal calprotectin increased ": 40.01812721442777, "Faeces soft ": 12.464777516777728, "Feeling of despair ": 2.5193538712117736, "Fibromyalgia ": 5.479513820979863, "Finger deformity ": 3.78846375066755, "Fistula ": 16.805968862712607, "Fistula discharge ": 63.574617661321135, "Food allergy ": 4.736377243973619, "Food intolerance ": 4.430173283832537, "Foot deformity ": 4.500188227793121, "Foreign body embolism ": 631.1768025196184, "Foreign body in respiratory tract ": 36.11607921342855, "Frequent bowel movements ": 15.288560856269516, "Fungal infection ": 2.86110139676079, "Fungal skin infection ": 4.630624753968936, "Furuncle ": 4.98678226308189, "Gastrointestinal disorder ": 2.3552203378368177, "Gastrointestinal infection ": 4.693973515550377, "Gastrointestinal inflammation ": 7.916630964978486, "Gastrointestinal mucosa hyperaemia ": 67.50825723639898, "Gastrointestinal oedema ": 6.804568812232067, "Gastrointestinal toxicity ": 3.413917061674866, "General symptom ": 10.94581230412594, "Glomerular filtration rate abnormal ": 3.759555549185874, "Glucose tolerance impaired ": 6.6923583982254105, "Grip strength decreased ": 4.385045785005532, "Groin pain ": 3.379010458470165, "Haematochezia ": 3.02475368462139, "Hepatic fibrosis ": 3.169660866236496, "Hepatic steatosis ": 3.389562218203732, "Hepatitis B ": 2.2108138111033178, "Herpes simplex oesophagitis ": 360.22519557019314, "Hidradenitis ": 47.26125021553986, "Hodgkin's disease ": 4.637521360406151, "Hyperphagia ": 16.399832867299157, "Hysterectomy ": 2.8364282911160057, "Ileostomy ": 15.658315811925988, "Immunodeficiency ": 7.502544293224453, "Immunosuppression ": 4.704860484842739, "Impaired quality of life ": 7.238404263682648, "Impaired work ability ": 2.8296923124761046, "Infection ": 2.634797379235464, "Inflammation ": 5.2420571725315765, "Inflammatory bowel disease ": 6.7775644416693845, "Inflammatory marker increased ": 4.740294612246738, "Injection site bruising ": 2.715843135814292, "Intentional dose omission ": 4.108916592193777, "Intervertebral disc disorder ": 3.1509625233342105, "Intervertebral disc protrusion ": 6.057971659353998, "Intestinal anastomosis ": 53.996061640104784, "Intestinal obstruction ": 2.1372937451896123, "Intestinal perforation ": 3.56124689584405, "Intestinal resection ": 18.2590565790706, "Intestinal stenosis ": 10.185518702842876, "Intestinal ulcer ": 23.68398022720706, "Investigation abnormal ": 13.012915817241517, "Iron deficiency ": 5.088668436612184, "Joint effusion ": 5.2913138708851495, "Joint injury ": 6.441841189722935, "Joint noise ": 14.273851830983068, "Joint range of motion decreased ": 8.955495527909804, "Joint space narrowing ": 60.52690974700181, "Joint stiffness ": 6.534394169315148, "Joint swelling ": 4.133262471655464, "Juvenile idiopathic arthritis ": 10.59574221614061, "Knee arthroplasty ": 5.858604215554467, "Knee operation ": 4.66465344599152, "Laboratory test abnormal ": 3.322679119811636, "Laparotomy ": 15.011547619204594, "Large intestinal stenosis ": 28.132556905663627, "Large intestinal ulcer ": 4.804388682901338, "Leg amputation ": 3.4564480786839056, "Ligament sprain ": 2.303245571688715, "Limb injury ": 2.4999468389191617, "Limb operation ": 7.862596051523624, "Liver function test abnormal ": 2.5244614658908384, "Localised infection ": 2.0152842500579995, "Loss of personal independence in daily activities ": 3.773238221986897, "Lower limb fracture ": 2.150251795159507, "Lupus-like syndrome ": 18.619915298052817, "Lyme disease ": 4.07583105417339, "Lymphoma ": 2.097079132268074, "Malignant melanoma ": 2.1377954818542277, "Malnutrition ": 3.149603411883763, "Medical device implantation ": 19.37971712124573, "Middle insomnia ": 3.608948557418156, "Mobility decreased ": 2.344447401538378, "Mouth ulceration ": 2.1600167926373794, "Mucous stools ": 5.501050560822975, "Multiple sclerosis ": 2.41132944218718, "Muscle tightness ": 3.774451684556418, "Musculoskeletal disorder ": 3.4607610254680607, "Musculoskeletal pain ": 2.216274590322169, "Musculoskeletal stiffness ": 3.5404132279728797, "Myasthenia gravis ": 2.363821166964887, "Neck pain ": 2.437523999855325, "Nephrolithiasis ": 2.129548316573213, "Nerve compression ": 5.211818867345266, "Nodule ": 3.267719446534155, "Nonspecific reaction ": 12.478184811274156, "Nystagmus ": 2.1876247276139984, "Obstruction ": 7.703538013323878, "Ophthalmoplegia ": 5.966586871166773, "Oral herpes ": 2.809506000810029, "Osteoarthritis ": 6.177999485760927, "Pathogen resistance ": 4.906327159919575, "Peripheral swelling ": 2.487884987268813, "Pilonidal disease ": 57.69823251673791, "Polyarthritis ": 4.9212726473584345, "Polyp ": 3.88680408797094, "Poor peripheral circulation ": 2.25676995813038, "Poor venous access ": 9.52025137472416, "Post procedural complication ": 2.323409032475936, "Post procedural infection ": 8.60113055895309, "Post-traumatic pain ": 49.12310336964346, "Postoperative wound infection ": 2.762556371754778, "Pouchitis ": 40.0502155324284, "Procedural pain ": 4.2973966967318935, "Proctalgia ": 3.142974378260089, "Proctitis ": 2.8911605061076124, "Product contamination physical ": 19.590340374175348, "Product label issue ": 8.52569055747612, "Pseudomonas infection ": 2.792358891822872, "Psoriasis ": 13.291624687832163, "Psoriatic arthropathy ": 9.390486611940275, "Pulmonary pain ": 3.3658356911039164, "Pulmonary tuberculosis ": 4.447103881061256, "Pulmonary vasculitis ": 12.26730195400268, "Purulent discharge ": 4.092517919917436, "Pustular psoriasis ": 5.002281045411307, "Pyoderma gangrenosum ": 6.2125717917968535, "Rectal haemorrhage ": 3.072863500269261, "Red blood cell sedimentation rate decreased ": 39.534305112580185, "Red blood cell sedimentation rate increased ": 9.640759914309262, "Respiratory syncytial virus infection ": 3.1163406970770247, "Respiratory tract congestion ": 2.681413897117869, "Retinal toxicity ": 30.68886444324845, "Rheumatoid arthritis ": 9.252504710501295, "Rheumatoid factor positive ": 6.0941831963380535, "Root canal infection ": 251.5805299526095, "Rotator cuff syndrome ": 2.549712236589772, "Sacroiliitis ": 14.500019471821634, "Salt craving ": 252.3229399113025, "Scar ": 2.311254836593597, "Seasonal allergy ": 2.5029228499892966, "Sensitivity to weather change ": 3.897885747503868, "Seronegative arthritis ": 15.34781210291506, "Shoulder operation ": 6.222094698634703, "Sinus congestion ": 2.035908287864176, "Sinus disorder ": 2.2613387640202336, "Sinusitis ": 2.542782332680828, "Sinusitis bacterial ": 18.20069535634932, "Sjogren's syndrome ": 4.729415034644246, "Skin cancer ": 3.101425179814654, "Skin induration ": 3.733315474051074, "Skin lesion ": 2.221126364538839, "Skin mass ": 3.278395838909885, "Skin plaque ": 3.4030039781789445, "Skin reaction ": 2.029658386540922, "Small intestinal obstruction ": 3.6270668390388057, "Spinal osteoarthritis ": 4.695183799158509, "Spinal stenosis ": 2.072433350261212, "Spondylitis ": 6.5385834498678665, "Squamous cell carcinoma ": 3.144724524155957, "Squamous cell carcinoma of skin ": 2.5019819602299544, "Stenosis ": 12.002309282281534, "Steroid dependence ": 31.95986689950306, "Stress ": 4.363558512458579, "Subcutaneous abscess ": 5.361809609389688, "Surgery ": 2.337949304889748, "Swollen joint count increased ": 8.157357656832843, "Synovitis ": 12.420267993527448, "Systemic lupus erythematosus ": 2.3803388454852783, "Tachyarrhythmia ": 7.293448300319148, "Temperature regulation disorder ": 4.074407710586363, "Tenosynovitis ": 3.207516355186352, "Thalassaemia minor ": 200.9054819402286, "Therapeutic product effect decreased ": 12.583150218611037, "Therapeutic product effect incomplete ": 5.335488103230087, "Therapeutic response shortened ": 17.508444467131778, "Therapy partial responder ": 4.228867058271397, "Tooth abscess ": 7.954898425754529, "Transfusion reaction ": 27.951435803193966, "Treatment failure ": 3.66524652690179, "Trismus ": 2.3332881177629363, "Tuberculosis ": 5.43598098610374, "Type 1 diabetes mellitus ": 2.6441424246613408, "Type 2 diabetes mellitus ": 4.883950880247271, "Ulcer ": 4.788352124919284, "Unevaluable event ": 3.974716538591281, "Uterine polyp ": 9.233408654059543, "Uveitis ": 5.890106344139372, "Viral tonsillitis ": 249.33489495330292, "Vitamin D decreased ": 2.649990869289151, "White matter lesion ": 10.186417692743928, "Wound complication ": 11.67614370224807, "Wound dehiscence ": 6.408743296619674, "Wound secretion ": 4.921689536004323, "Wrist deformity ": 21.21109314334856}
\ No newline at end of file
+{"Diarrhoea": 2.778307730197742, "Neutropenia": 10.413262667693711, "Thrombocytopenia": 5.795474017641774}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/536.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/536.json
index bb9b7e074fa..7c4cf9b287b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/536.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/536.json
@@ -1 +1 @@
-{"Agranulocytosis ": 2.2458824067425622, "Anaemia ": 13.81168275832488, "Blood alkaline phosphatase increased ": 3.106180453629597, "Blood bilirubin increased ": 2.9637077820045667, "Blood lactate dehydrogenase increased ": 7.454170133962839, "Blood sodium decreased ": 8.21096265461587, "Blood urea increased ": 5.375157798213568, "Bone marrow failure ": 8.994056512647528, "Death ": 5.825803702001005, "Decreased appetite ": 4.286295818718715, "Disease progression ": 4.088221527901891, "Febrile neutropenia ": 14.75578955889442, "Haematotoxicity ": 19.74903657799025, "Haemoglobin decreased ": 4.2356837408112336, "Ileus ": 10.828623647493885, "Interstitial lung disease ": 5.31336863781602, "Leukopenia ": 11.89923373865077, "Myelosuppression ": 5.49694849873427, "Neutropenia ": 7.038924877404578, "Neutrophil count decreased ": 37.82139309258236, "Pancytopenia ": 14.407835973075754, "Platelet count decreased ": 24.06033229321545, "Protein total decreased ": 39.56100020244674, "Red blood cell count decreased ": 59.5453019001828, "Sepsis ": 2.5976700428449946, "Small cell lung cancer ": 105.22367541660442, "Thrombocytopenia ": 8.223117850009672, "White blood cell count decreased ": 24.24588415432542}
\ No newline at end of file
+{"Body temperature increased": 10.32958251899102, "Crying": 92.69704863735092, "Decreased appetite": 4.664067977519861, "Diarrhoea": 2.0064075999376545, "Hypotonic-hyporesponsive episode": 271.509093342318, "Irritability": 15.449408688737986, "Pyrexia": 3.3333582579864034, "Restlessness": 15.066447653870318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/537.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/537.json
index b273d4c572a..13fdeb69859 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/537.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/537.json
@@ -1 +1 @@
-{"Acute kidney injury ": 5.384028878342408, "Angioedema ": 4.821075652509352, "Blood creatine phosphokinase increased ": 2.109052229109457, "Blood creatinine increased ": 4.936031143424768, "Blood pressure decreased ": 2.1469690517506748, "Blood pressure fluctuation ": 7.503337707575477, "Blood pressure increased ": 4.319102189370401, "Cataract ": 5.047155231959379, "Completed suicide ": 4.547487303790689, "Eye pain ": 4.479097198272771, "Hyperglycaemia ": 2.5795252685950327, "Hyperkalaemia ": 4.6060379624442, "Hypokalaemia ": 26.44071193552828, "Hyponatraemia ": 14.822155081241691, "Hypotension ": 4.691362883981481, "Intentional overdose ": 2.0235000204827176, "Liver function test abnormal ": 3.499071064472354, "Oedema peripheral ": 2.47609353786058, "Product substitution issue ": 16.203726705119042, "Renal impairment ": 5.410987786738501, "Restlessness ": 2.075349399758765, "Stevens-Johnson syndrome ": 5.435724155453702, "Suicide attempt ": 2.6614860996521035, "Swelling face ": 3.839674414283453, "Systemic lupus erythematosus ": 4.660739266470458, "Therapeutic response unexpected ": 4.561638438198443, "Toxicity to various agents ": 3.388301594537451, "Urinary tract infection ": 2.2699568972014603, "Vision blurred ": 2.686706493226288}
\ No newline at end of file
+{"Allergy to metals": 610.2763127030163, "Apathy": 8.161867337607076, "Child maltreatment syndrome": 3416.1109959636137, "Crying": 27.83776619680601, "Cyanosis": 11.403233578709486, "Erythema": 2.0385290936667406, "Febrile convulsion": 53.74010426105814, "Hyperpyrexia": 169.63819112844877, "Hypotonia": 14.953904631688031, "Hypotonic-hyporesponsive episode": 100.34455324278557, "Irritability": 7.457766920929498, "Neurodermatitis": 101.14428493815488, "Opisthotonus": 109.67758439435184, "Pallor": 13.750865198494292, "Pyrexia": 4.872603840393505, "Reaction to excipient": 158.01937603946033, "Restlessness": 14.785199530569392, "Scratch": 248.62180176241336, "Screaming": 68.83905875963742, "Skin wound": 634.1460256189082, "Sleep disorder": 5.602653087644858, "Sudden infant death syndrome": 234.6567004896544, "Unresponsive to stimuli": 6.372272466333613, "Urticaria": 4.189664037585972, "Vaccination site discolouration": 260.6918853920437, "Vaccination site eczema": 551.143739752107, "Vaccination site erythema": 14.862515432037831, "Vaccination site granuloma": 1511.2063477437218, "Vaccination site hypertrichosis": 1036.1351899356696, "Vaccination site hypertrophy": 1777.208906920939, "Vaccination site irritation": 229.8750314901758, "Vaccination site pruritus": 35.2598687676903, "Vaccination site rash": 19.683592590916295, "Vaccination site swelling": 7.553123867549315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/538.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/538.json
index a1c6cabbd51..24f558b397e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/538.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/538.json
@@ -1 +1 @@
-{"Acute respiratory distress syndrome ": 2.1424906772319168, "Acute respiratory failure ": 2.442643023124855, "Adrenal insufficiency ": 21.786673113041044, "Adrenal suppression ": 80.51600253342541, "Adrenocortical insufficiency acute ": 47.97235498325499, "Adverse drug reaction ": 2.2134298841100817, "Angiopathy ": 13.063279941254985, "Apnoea ": 5.681993997346934, "Aspergillus infection ": 5.765697820335313, "Asthmatic crisis ": 3.7077742899266433, "Auditory disorder ": 11.130338020192449, "Bacteraemia ": 3.798089633585603, "Blood bicarbonate decreased ": 12.969970740445046, "Blood lactic acid increased ": 5.0071046681924125, "Blood pH decreased ": 14.501248754679011, "Blood potassium decreased ": 2.4602424420280644, "Body temperature fluctuation ": 9.525873603337748, "Bone disorder ": 4.187236907389356, "Bronchiectasis ": 10.235221294369191, "Bronchospasm ": 2.039325425910312, "Burning sensation ": 3.305793005749032, "Caesarean section ": 6.668218368323991, "Calcinosis ": 34.185383932214165, "Cardiomegaly ": 3.627989986137317, "Cataract ": 3.04694164686073, "Central obesity ": 37.5807670380101, "Cerebral disorder ": 17.567016299061585, "Clonus ": 10.81897970251229, "Colitis ulcerative ": 2.0136206462918618, "Condition aggravated ": 2.3490571979750725, "Cortisol decreased ": 27.446090241778634, "Craniocerebral injury ": 16.107018054627154, "Crepitations ": 8.618088568997015, "Cushing's syndrome ": 33.789931168865145, "Cushingoid ": 8.839438022693637, "Decreased interest ": 29.50955484596742, "Dermatitis ": 2.944932120808041, "Dermatitis atopic ": 9.034436489467485, "Dermatitis bullous ": 3.962940278076703, "Device dislocation ": 52.529716803804256, "Device malfunction ": 9.124717752478968, "Disease recurrence ": 4.369353163680615, "Disseminated intravascular coagulation ": 2.2491161818492844, "Diverticulum ": 5.198682800146693, "Drug hypersensitivity ": 2.152735140128359, "Drug ineffective ": 2.577950327990197, "Drug interaction ": 2.152182351230056, "Drug level increased ": 2.15012736949981, "Dry skin ": 2.5700438672489736, "Duodenal ulcer perforation ": 2.440794762166317, "Dysuria ": 3.5569242428419865, "Ear infection ": 2.8365113084518776, "Eczema ": 7.207423631085216, "Electroencephalogram abnormal ": 6.242262733660415, "Emotional disorder ": 3.261860886260139, "Erythema ": 2.7268610672384224, "Exposure during pregnancy ": 3.111906826090044, "Eye swelling ": 2.527822239397661, "Flushing ": 2.610534132611916, "Foetal death ": 6.00608723800146, "Foetal exposure during pregnancy ": 2.379052348017592, "Foetal growth restriction ": 3.007923239590444, "Fungal infection ": 3.5296089246069364, "Gingival disorder ": 30.727243669486285, "Growth retardation ": 8.08080788756608, "Hip arthroplasty ": 5.247101754103886, "Hypercapnia ": 14.751160631951256, "Hypercholesterolaemia ": 3.2245078471824704, "Hyperventilation ": 3.053036580347279, "Hypoacusis ": 3.279165838952511, "Hypocalcaemia ": 2.3939519173738706, "Hypomagnesaemia ": 3.821049958365553, "Hypophosphataemia ": 9.88939523519174, "Hypothalamic pituitary adrenal axis suppression ": 137.89566713230414, "Incorrect product administration duration ": 2.0664840836190974, "Incorrect route of product administration ": 2.4767807809314366, "Inflammation ": 2.6001489732830843, "Knee arthroplasty ": 6.292799886246887, "Lip swelling ": 2.785069484812841, "Lipase increased ": 3.4920478303509577, "Live birth ": 10.80564277732502, "Lung hyperinflation ": 34.42613259308436, "Maternal exposure during pregnancy ": 3.014403411871577, "Medication error ": 5.173922249640948, "Metabolic acidosis ": 2.072632917201095, "Mobility decreased ": 2.9660269887826183, "Multiple organ dysfunction syndrome ": 4.937040480149458, "Multiple-drug resistance ": 6.838664909761753, "Nerve compression ": 20.805389158093075, "Neuralgia ": 5.3206100426639455, "Obstructive airways disorder ": 2.239139349366045, "Oedema ": 2.6393992151435755, "Oral disorder ": 13.173859414567607, "Osteoarthritis ": 2.1989195427880563, "Oxygen saturation decreased ": 2.0839877497959094, "PCO2 increased ": 42.12694531530786, "PO2 decreased ": 28.430124957901445, "Pain of skin ": 3.547850538933444, "Perfume sensitivity ": 114.31224896336468, "Perineal pain ": 114.3506496984886, "Peripheral coldness ": 3.55626541674488, "Peripheral venous disease ": 6.344541821465205, "Pituitary tumour benign ": 18.686926283494053, "Post procedural infection ": 10.70054335585496, "Premature baby ": 5.016327798363761, "Premature delivery ": 9.296888917729335, "Premature labour ": 5.779270125947948, "Preterm premature rupture of membranes ": 105.9744567718501, "Quality of life decreased ": 3.322878404175163, "Radiculopathy ": 12.761698742674035, "Rash pruritic ": 2.190773027960508, "Respiratory acidosis ": 10.074876529457978, "Respiratory arrest ": 2.9870040819133936, "Respiratory depression ": 2.33978335419846, "Respiratory disorder ": 4.951970720157633, "Respiratory rate increased ": 5.505813236962944, "Scab ": 5.425677990819779, "Secondary adrenocortical insufficiency ": 13.431084300848052, "Sensitive skin ": 4.745629469118601, "Skin atrophy ": 27.395409780727213, "Skin burning sensation ": 18.185668122103763, "Skin exfoliation ": 14.6373037950837, "Skin fissures ": 6.2804794138788855, "Skin haemorrhage ": 3.405066625463615, "Skin hyperpigmentation ": 14.925828477450448, "Skin infection ": 16.482734146931246, "Skin irritation ": 10.504449747979775, "Skin lesion ": 4.589618615293853, "Skin swelling ": 11.491438452590453, "Skin weeping ": 305.24579596888844, "Skin wrinkling ": 54.00945368920078, "Sleep disorder due to a general medical condition ": 4.125760092701747, "Staphylococcal infection ": 2.064096075479869, "Steroid withdrawal syndrome ": 475.4832521146338, "Tachypnoea ": 2.38730204436444, "Temperature regulation disorder ": 12.169902675443296, "Tendonitis ": 4.708546931594012, "Therapeutic product effect incomplete ": 2.049848658028277, "Thyrotoxic crisis ": 21.834880983549144, "Topical steroid withdrawal reaction ": 237.4904148028552, "Toxic epidermal necrolysis ": 3.8657258517792914, "Urinary tract disorder ": 26.60324510581443, "Wheezing ": 3.379292472098378}
\ No newline at end of file
+{"Abscess": 2.525621428733284, "Administration site erythema": 8.913697627565753, "Administration site reaction": 19.759136146347267, "Adverse reaction": 2.653995176128208, "Atypical pneumonia": 10.28141760509201, "Bacterial infection": 3.2013226272775888, "Blood immunoglobulin G decreased": 36.23493939766714, "Bronchiectasis": 3.5290916894420703, "Bronchitis": 7.5306867379931, "Cardiac operation": 4.954489909774196, "Catheterisation cardiac": 5.830117459159651, "Cellulitis": 5.16096964056848, "Chemotherapy": 9.492918835545712, "Cholecystectomy": 6.661901925390961, "Chronic inflammatory demyelinating polyradiculoneuropathy": 58.01852144054012, "Chronic obstructive pulmonary disease": 2.685479986614635, "Clostridium difficile infection": 3.739421721930439, "Cystitis": 2.3998653903890856, "Diverticulitis": 3.3352560015802117, "Ear infection": 9.060749119542178, "Escherichia infection": 5.255138738924435, "Eye infection": 5.554562477972983, "Fungal infection": 2.0083459946113664, "Gastric infection": 13.849102544766325, "Gastroenteritis viral": 5.269274548160809, "Hepatitis B": 9.948954687832384, "Hepatitis B core antibody positive": 38.15186738197758, "Hepatitis B surface antibody positive": 51.721159695051824, "Hepatitis B virus test positive": 50.47830427418024, "Hospitalisation": 3.6519207747497457, "Ill-defined disorder": 3.575817535833825, "Immunoglobulins decreased": 33.705963008290006, "Incorrect drug administration rate": 7.360437930170771, "Infection": 4.4477823322035, "Infusion site abscess": 445.6791247779289, "Infusion site bruising": 454.0912088326572, "Infusion site cellulitis": 240.0035130832028, "Infusion site discharge": 309.60892174152303, "Infusion site discolouration": 109.1812227315124, "Infusion site erythema": 219.78482144089944, "Infusion site extravasation": 15.36360875389692, "Infusion site haemorrhage": 113.78499873608274, "Infusion site induration": 163.47307428434308, "Infusion site infection": 116.2209149337925, "Infusion site inflammation": 68.70267233407614, "Infusion site irritation": 108.68076930071598, "Infusion site mass": 170.48858648857654, "Infusion site nodule": 991.936128420792, "Infusion site oedema": 49.467740061401805, "Infusion site pain": 117.67972067746966, "Infusion site pruritus": 261.0206380197223, "Infusion site rash": 137.7835572330428, "Infusion site reaction": 41.14545870528124, "Infusion site scab": 505.8812969775844, "Infusion site swelling": 265.6991137539359, "Infusion site ulcer": 396.8216973003799, "Infusion site urticaria": 296.2544242157266, "Infusion site vesicles": 126.2527781221119, "Infusion site warmth": 263.1970730381342, "Injection site bruising": 2.142211683998021, "Injection site discharge": 22.36251436651957, "Injection site discomfort": 3.219393470001869, "Injection site erythema": 3.594357504746206, "Injection site induration": 5.374292914229049, "Injection site infection": 11.658155599265363, "Injection site irritation": 12.611525085319895, "Injection site mass": 5.0829962713902646, "Injection site necrosis": 13.804170224412935, "Injection site nodule": 7.392084505112527, "Injection site oedema": 2.160613153785988, "Injection site pruritus": 4.276693754233053, "Injection site rash": 4.793215582644109, "Injection site swelling": 2.4282649304612463, "Injection site ulcer": 19.712268372051007, "Injection site urticaria": 7.529418305774959, "Insurance issue": 30.608312599723156, "Intestinal obstruction": 2.313789420157242, "Kidney infection": 10.656839168564728, "Knee operation": 5.82315326293442, "Laryngitis": 2.720504778039785, "Limb operation": 7.888981930659752, "Liquid product physical issue": 4.495914957062828, "Lower respiratory tract infection": 2.682925255139002, "Lymphoma": 2.254165514258733, "Meningitis": 4.400028384221042, "Meningitis aseptic": 41.97906138911333, "Migraine": 2.597212908710439, "Nephrolithiasis": 4.988279803810406, "No adverse event": 47.426433805965466, "Osteomyelitis": 3.66101846564404, "Pharyngeal swelling": 2.2989709435581696, "Pharyngitis streptococcal": 7.548730092672092, "Pneumonia": 6.279996121972299, "Product dose omission issue": 2.6630302472560783, "Product supply issue": 6.870804601413592, "Product use complaint": 3.330935354130142, "Productive cough": 2.8400340721295656, "Pseudomonas infection": 5.666037560804693, "Recalled product administered": 34.94568930985255, "Respiratory syncytial virus infection": 4.198888362557592, "Respiratory tract congestion": 2.994839541279018, "Respiratory tract infection": 21.68055403648957, "Sinus congestion": 3.381141153189217, "Sinus disorder": 5.2651886750147465, "Sinus operation": 58.7737320079036, "Sinusitis": 15.257509065273869, "Skin infection": 7.772037317914322, "Skin mass": 2.56211388630661, "Skin reaction": 2.4062420441164867, "Spinal operation": 6.167453914614403, "Sputum discoloured": 4.46688184690968, "Staphylococcal infection": 9.880955893343156, "Stent placement": 5.31880430611129, "Streptococcal infection": 9.908606405164807, "Surgery": 4.641144851334939, "Suspected transmission of an infectious agent via product": 90.43640307250324, "Therapy cessation": 9.45002391931258, "Therapy change": 10.995644492319196, "Therapy interrupted": 20.118399943103604, "Throat tightness": 2.711913319500153, "Thrombosis": 2.8512316694494984, "Tooth abscess": 6.933241907253326, "Tooth infection": 4.309896959896177, "Transient ischaemic attack": 2.062837444756539, "Unevaluable event": 6.283238407721695, "Upper respiratory tract infection": 8.360195266732386, "Urinary tract infection": 3.191049329827748, "Urine output decreased": 6.543257373458443, "Viral infection": 4.498124933676181, "Weight fluctuation": 10.58519775465012, "Wound infection": 3.262221942324613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/539.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/539.json
index f848194a991..3c3ed914f1a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/539.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/539.json
@@ -1 +1 @@
-{"Acute kidney injury ": 20.92162756123594, "Hypercalcaemia ": 408.7547512422973, "Hypervitaminosis ": 12004.371426589903, "Intentional product misuse ": 32.936759697651475, "Off label use ": 5.461430253220837}
\ No newline at end of file
+{"Abscess limb": 2.4239262271517625, "Accident": 5.134202156402866, "Accident at work": 5.5316710068475805, "Accidental underdose": 57.48357870315213, "Addison's disease": 3.1336223605258247, "Amputation": 10.00894076766185, "Aneurysm": 3.563080950410208, "Angiopathy": 2.9590635681604693, "Animal bite": 5.502811826039766, "Ankle fracture": 3.3332032486259875, "Anti-insulin antibody": 43.083850655068176, "Anti-insulin antibody increased": 45.96671666857312, "Anti-insulin antibody positive": 44.50685455279834, "Apgar score low": 2.0033631762623294, "Arterial disorder": 2.5889196502540712, "Arterial occlusive disease": 6.249195683101624, "Arterial stenosis": 4.071161585150862, "Arteriovenous malformation": 8.959563217532247, "Arthritis": 3.2926881945950206, "Arthropod bite": 2.278585449235568, "Astigmatism": 2.738751409687289, "Autonomic neuropathy": 3.841306587036304, "Back disorder": 3.32591294201659, "Back injury": 2.055107300738878, "Barrett's oesophagus": 3.39688373276407, "Blindness": 12.932130858783392, "Blindness transient": 2.168023922964283, "Blindness unilateral": 11.9967899419334, "Blood glucose abnormal": 41.51675897751431, "Blood glucose decreased": 61.93450262721566, "Blood glucose fluctuation": 30.05435965750833, "Blood glucose increased": 43.88775329025724, "Blood insulin increased": 23.709434749887613, "Blood ketone body": 27.730980433168995, "Blood ketone body increased": 16.00010493184288, "Blood ketone body present": 3.643609260462625, "Blood pressure abnormal": 2.2890633085570515, "Blood zinc decreased": 27.847491024637687, "Brain injury": 3.5958092061689064, "Brain neoplasm": 3.751584020368247, "Brain neoplasm benign": 13.16960319931762, "Cardiac disorder": 4.054906781398397, "Cardiac failure congestive": 3.449460396421177, "Cardiac valve disease": 3.1165519547327434, "Carotid artery occlusion": 5.609933666985889, "Carpal tunnel syndrome": 4.592916441336316, "Cataract": 9.839602503008166, "Cerebral disorder": 3.4571504921143634, "Cerebrovascular accident": 4.379037298059818, "Cervical vertebral fracture": 3.6205491175687423, "Chronic obstructive pulmonary disease": 2.071413852776756, "Colon cancer": 2.863050597621588, "Coma": 2.469981464661914, "Concussion": 2.641647962907085, "Coronary artery bypass": 2.546450620576539, "Coronary artery disease": 2.652336233628932, "Coronary artery occlusion": 3.982642055862291, "Cutaneous amyloidosis": 55.94232430957943, "Dawn phenomenon": 51.43910803475495, "Deafness unilateral": 2.9728908494906188, "Dementia": 6.700138928755196, "Dementia Alzheimer's type": 9.089867364154795, "Diabetes mellitus inadequate control": 14.300533916613396, "Diabetic blindness": 85.28995832096584, "Diabetic coma": 28.602296636416888, "Diabetic complication": 35.374853890799834, "Diabetic eye disease": 32.44686482396717, "Diabetic foot": 23.947018248427177, "Diabetic foot infection": 12.7728041407869, "Diabetic gangrene": 21.283079157421508, "Diabetic gastroparesis": 21.03276600434173, "Diabetic hyperglycaemic coma": 22.07770547213865, "Diabetic ketoacidosis": 19.349638678136333, "Diabetic ketoacidotic hyperglycaemic coma": 18.37615649644065, "Diabetic ketosis": 8.8618776803873, "Diabetic metabolic decompensation": 3.3125774080278494, "Diabetic nephropathy": 10.163575927272923, "Diabetic neuropathy": 18.282635527128416, "Diabetic retinopathy": 51.53359234562024, "Drug hypersensitivity": 2.2817571703246524, "Drug ineffective": 2.281168165237682, "Expired product administered": 8.425662931325101, "Exposure via breast milk": 2.8078786467384576, "Extra dose administered": 3.2149441055627075, "Eye disorder": 5.448398075441043, "Eye haemorrhage": 17.46089326017799, "Eye injury": 3.8099002206789296, "Eye laser surgery": 12.7280785954752, "Eye operation": 2.9593643185148477, "Face injury": 2.2147884157372757, "Fall": 3.0326311155877645, "Fat tissue increased": 4.636440092893343, "Feeding disorder": 2.239580433468652, "Feeling abnormal": 2.0172790769320765, "Femur fracture": 2.5050691763079938, "Fine motor skill dysfunction": 2.641471997360679, "Food poisoning": 3.091050951809078, "Foot fracture": 2.203023074616803, "Gait inability": 2.160987136137645, "Gangrene": 9.006841849053604, "Gastroenteritis viral": 2.1760312672208184, "Gestational hypertension": 3.91957520817228, "Glaucoma": 7.709389007178751, "Glucose-6-phosphate dehydrogenase deficiency": 95.23597343459136, "Glycosylated haemoglobin abnormal": 9.74944499130071, "Glycosylated haemoglobin decreased": 6.057966491246829, "Glycosylated haemoglobin increased": 30.89803240118812, "Head injury": 3.5913628101548296, "Hepatitis A": 16.22699915260514, "Hernia": 2.628828722438105, "Herpes simplex": 3.045299912521568, "Hip fracture": 3.4040123522881176, "Humerus fracture": 2.309342195435577, "Hunger": 5.660581193600192, "Hypercoagulation": 2.9039004406859408, "Hyperglycaemia": 12.638225090839653, "Hyperglycaemic unconsciousness": 39.03968496107499, "Hyperinsulinaemic hypoglycaemia": 60.11148396594709, "Hyperkeratosis": 2.3333756488442043, "Hypermetropia": 2.941053191848288, "Hypoacusis": 4.181135791437674, "Hypoglycaemia": 23.834481909556448, "Hypoglycaemia neonatal": 7.40201189227814, "Hypoglycaemia unawareness": 81.6082116097719, "Hypoglycaemic coma": 26.64688933407961, "Hypoglycaemic encephalopathy": 9.389216812638152, "Hypoglycaemic seizure": 38.83252482378238, "Hypoglycaemic unconsciousness": 38.737169970777565, "Hypophagia": 2.138222404812998, "Illness": 2.417119764207049, "Impaired gastric emptying": 6.906629360592932, "Impaired healing": 2.2494534851634427, "Incoherent": 2.6163657281569965, "Incorrect dosage administered": 5.079485179653728, "Incorrect dose administered": 17.719790799938167, "Incorrect product administration duration": 9.035814555325114, "Incorrect product dosage form administered": 7.7613840442941395, "Incorrect product formulation administered": 25.888434204392727, "Increased insulin requirement": 14.366699444969775, "Infarction": 2.0354744103988613, "Infusion site infection": 6.380572445495285, "Injection site atrophy": 5.540685252400602, "Injection site bruising": 7.220145160667847, "Injection site haemorrhage": 5.5163105295839365, "Injection site hypersensitivity": 3.5749155443804512, "Injection site infection": 2.6273955430601976, "Injection site injury": 5.367894386409123, "Injection site irritation": 2.584489565798849, "Injection site mass": 5.393240239996179, "Injection site scar": 13.947036794018963, "Injection site urticaria": 4.409617214967412, "Injury associated with device": 14.483191720946513, "Insulin C-peptide decreased": 30.74409091099713, "Insulin resistance": 57.628252807775496, "Insulin resistant diabetes": 78.20119097978912, "Intercepted product dispensing error": 52.14924877783667, "Intercepted product selection error": 104.33722136848446, "Intervertebral disc degeneration": 2.248631085804534, "Intervertebral disc protrusion": 2.973876968609263, "Intracranial aneurysm": 2.024296467413852, "Jaundice neonatal": 3.3853661803101547, "Joint injury": 3.175165744592051, "Ketoacidosis": 13.481458909057322, "Ketonuria": 5.066084236450653, "Ketosis": 10.904558937644586, "Large for dates baby": 18.64954912545092, "Leg amputation": 5.516417155492803, "Ligament disorder": 8.466070044186285, "Ligament rupture": 2.0413698928486923, "Limb deformity": 2.250095462466253, "Limb injury": 6.068243621239761, "Lip injury": 3.5037420346326256, "Lipids increased": 2.8732246046652703, "Lipoatrophy": 7.627360713403401, "Lipohypertrophy": 5.7232388522212485, "Lipoma": 2.9311273266988853, "Localised infection": 7.845119372860901, "Loss of consciousness": 3.46883546230706, "Lower limb fracture": 4.079293924346634, "Macular degeneration": 6.8730101542488296, "Macular oedema": 4.321612785177637, "Maculopathy": 2.8347238038919294, "Malabsorption from injection site": 48.65335160647518, "Malnutrition": 10.112903835487623, "Medication error": 3.285466832173141, "Memory impairment": 4.055025420757174, "Meniscus injury": 2.413168073626464, "Microalbuminuria": 18.042419851927026, "Multi-organ disorder": 49.34086747334072, "Musculoskeletal disorder": 2.0096572172203158, "Myocardial infarction": 3.3306492376912646, "Myopia": 3.418048153878936, "Neck injury": 5.253615994472543, "Neoplasm malignant": 2.7014536227219765, "Neovascular age-related macular degeneration": 3.593758798965881, "Nerve compression": 3.8692088440114976, "Nerve injury": 3.1428880003393664, "Neuropathic arthropathy": 41.50384132877456, "Neuropathy peripheral": 3.8668195824158778, "Nonspecific reaction": 3.319760901951688, "Nosocomial infection": 2.330745816475938, "Osteomyelitis": 6.0637094495783765, "Overweight": 4.336293904284255, "Pancreatic abscess": 17.14555952848887, "Pancreatic disorder": 11.37176756735334, "Pancreatic failure": 7.267463030229279, "Parkinson's disease": 3.8718907719869913, "Patella fracture": 2.802389600716653, "Pelvic fracture": 2.9772735611080363, "Pericardial effusion": 3.0704930126112697, "Peripheral artery occlusion": 3.4567949964399074, "Peripheral vascular disorder": 2.0244173817163587, "Pollakiuria": 2.1065207739076603, "Poor peripheral circulation": 5.701978874365637, "Poor quality product administered": 3.0792652341296667, "Post procedural complication": 4.741299789569399, "Post procedural infection": 3.640074564430168, "Postoperative wound infection": 3.218317673877612, "Postprandial hypoglycaemia": 16.06678509952666, "Pre-eclampsia": 4.591032391063967, "Premature baby": 2.4918112493421383, "Premature labour": 2.218272342325548, "Presbyopia": 6.144242047071026, "Product administration error": 2.086902483046888, "Product dispensing error": 6.752269901843565, "Product dose omission issue": 6.184277275895991, "Product name confusion": 10.606036935188929, "Product storage error": 14.617898371481983, "Product tampering": 19.281774508222444, "Prostatic disorder": 2.230417900787471, "Pulmonary oedema": 2.612933907454851, "Rectal cancer": 2.0436252451464925, "Renal disorder": 5.0495501178812106, "Renal transplant": 4.122826716448303, "Retinal detachment": 8.587286504986132, "Retinal disorder": 10.5216878081244, "Retinal haemorrhage": 5.029519128158021, "Retinal injury": 9.023831652987186, "Retinal tear": 5.771815404008092, "Retinopathy": 14.154685299453254, "Rhinitis allergic": 2.931640416771561, "Rib fracture": 2.152803621970888, "Road traffic accident": 7.132594840233058, "Rotator cuff syndrome": 2.913458050938301, "Scar": 2.944440668168669, "Shock hypoglycaemic": 31.951748661003386, "Shoulder fracture": 5.059729042021213, "Skin ulcer": 2.821101959072882, "Sleep apnoea syndrome": 2.530167354132853, "Snoring": 7.8903065307983935, "Sopor": 7.000102423407814, "Spinal column injury": 3.4576301741854403, "Spinal disorder": 2.175895895090062, "Spinal stenosis": 3.140837461575573, "Staphylococcal infection": 2.305603823641426, "Stress": 4.736746683055314, "Suspected transmission of an infectious agent via product": 8.472204952114653, "Therapeutic product effect delayed": 6.786183886353623, "Therapeutic product effect increased": 2.3377873567004523, "Therapeutic response delayed": 9.701570799173686, "Thirst": 2.5034882916015917, "Throat cancer": 2.4846155435260826, "Thyroid disorder": 6.992258380853155, "Toe amputation": 7.326732968451391, "Trigger finger": 15.33742399760898, "Underdose": 5.256483355881013, "Upper limb fracture": 2.1465817035805768, "Urine ketone body present": 10.57261347799306, "Vascular graft": 4.523214037666957, "Vascular occlusion": 8.35413837548493, "Vein disorder": 2.242319400603672, "Venous occlusion": 2.2699410441649097, "Visual acuity reduced": 2.261748824042095, "Visual impairment": 6.828129164147506, "Vitreous haemorrhage": 3.6564716008146103, "Weight abnormal": 4.975718342053632, "Weight decreased": 2.2504572642866565, "Weight increased": 2.677304884856205, "Wound complication": 2.2230443290217243, "Wound infection": 3.0539794830308247, "Wrong patient received product": 7.186967733944446, "Wrong product administered": 26.60027806653665, "Wrong technique in product usage process": 3.754923231788025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/54.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/54.json
index b2257d01b48..3daa29362d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/54.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/54.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.357130840705633, "Alanine aminotransferase increased ": 2.0029074851168747, "Amnesia ": 2.722934579715965, "Aspartate aminotransferase increased ": 2.28943919081107, "Coma ": 2.2575438490669297, "Completed suicide ": 4.259953852420468, "Depression ": 2.4672795991243306, "Diabetes mellitus ": 2.733659929445376, "Drug hypersensitivity ": 3.0030386377431832, "Drug interaction ": 4.139369269879214, "Exposure during pregnancy ": 2.3168431560993987, "Hyperglycaemia ": 2.932935963249306, "Hypersensitivity ": 2.4495782522228144, "Intentional overdose ": 2.10938882077663, "Intentional product misuse ": 2.113627040119439, "Multiple organ dysfunction syndrome ": 5.4626420270326665, "Pancytopenia ": 2.192959408731116, "Stevens-Johnson syndrome ": 4.412685173382017, "Suicidal ideation ": 2.0736348445088155, "Suicide attempt ": 3.4435101199441016, "Toxicity to various agents ": 3.397317101549877, "Unevaluable event ": 12.077456970166384}
\ No newline at end of file
+{"Drug ineffective": 3.599852378254514, "Product use in unapproved indication": 21.37438387914948}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/540.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/540.json
index 6ecf0b8c6a0..b7e9a422865 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/540.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/540.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 30.41008111356076, "Anaemia ": 2.7775273851548388, "Bone pain ": 8.953866926559531, "Haemoglobin decreased ": 5.15317163087806, "Platelet count increased ": 58.28767027844895, "Splenomegaly ": 48.70300139290743, "Thrombocytopenia ": 2.2886327749829336, "Weight increased ": 3.028125320974097}
\ No newline at end of file
+{"Acute respiratory distress syndrome": 2.959360492051966, "Anaphylactic reaction": 3.336911290583924, "Anaphylactoid reaction": 9.032066298486807, "Anti factor VIII antibody positive": 24.89879808887865, "Autoimmune haemolytic anaemia": 14.196080412902733, "Bacteraemia": 3.02087071319968, "Blood immunoglobulin G decreased": 42.01471670088924, "Cardiogenic shock": 2.341307167986012, "Coombs direct test positive": 98.71477637316032, "Coronary artery aneurysm": 125.00462914750617, "Cytomegalovirus infection": 3.6665860211818, "Cytomegalovirus viraemia": 7.950372095493082, "Deep vein thrombosis": 2.488308234020033, "Dermatomyositis": 9.957327503069898, "Disseminated intravascular coagulation": 2.739386876042976, "Drug effective for unapproved indication": 131.17409318499827, "Drug ineffective": 5.7003662818087895, "Drug ineffective for unapproved indication": 107.16364351609514, "Drug resistance": 5.124773869719335, "Dyshidrotic eczema": 27.5628483320006, "Ear infection": 3.5370700636436294, "Embolism": 5.010424785076559, "Encephalitis": 2.3338591239490163, "Encephalitis autoimmune": 11.242805722955936, "Epstein-Barr virus infection": 4.607077610382689, "Exposure during pregnancy": 5.456963072708195, "Febrile nonhaemolytic transfusion reaction": 81.72025550461674, "Foetal death": 5.000896459745274, "Foetal exposure during pregnancy": 4.766632345459989, "Foetal growth restriction": 4.505419817437125, "Guillain-Barre syndrome": 2.3014325447121804, "Haemolysis": 41.10746564468607, "Haemolytic anaemia": 34.21681370734074, "Hemianopia homonymous": 28.925994433148357, "Hepatitis B core antibody positive": 42.89750223661919, "Hepatitis B surface antibody positive": 55.18924826040399, "Hepatitis C": 5.7721307846113294, "Hypervolaemia": 3.705436990876408, "Hypoxia": 2.9991056898865542, "Incorrect drug administration rate": 18.3238147281793, "Infusion related reaction": 2.6265451572171536, "Infusion site bruising": 55.14515716546533, "Infusion site erythema": 15.549653054716249, "Infusion site haemorrhage": 68.80740742910157, "Infusion site pain": 13.453912482055925, "Infusion site pruritus": 24.76123191038789, "Intentional product use issue": 9.447971532117869, "Ischaemic stroke": 2.2106194820422944, "Low birth weight baby": 5.624243711200443, "Lupus-like syndrome": 5.194379405222399, "Maternal exposure during pregnancy": 3.2523705733087325, "Meningitis": 3.0682541172442934, "Meningitis aseptic": 101.84303491415676, "Misleading laboratory test result": 440.5866493491976, "Multiple-drug resistance": 11.0300676048815, "Myasthenia gravis": 3.769224988748321, "Myositis": 3.272246203064949, "Nephrotic syndrome": 2.502888953601884, "No adverse event": 36.74473837570227, "Off label use": 6.793347311819401, "Post procedural complication": 5.860460458846941, "Posterior reversible encephalopathy syndrome": 18.230141699028863, "Premature baby": 5.066097186074768, "Premature delivery": 2.3200932128313845, "Product use in unapproved indication": 6.2217301523849455, "Pulmonary embolism": 2.983805953206057, "Respiratory distress": 2.228285120814813, "Respiratory failure": 2.1763832499451805, "Respiratory tract infection": 2.492866455782184, "Status epilepticus": 3.737681102618512, "Stress cardiomyopathy": 4.81380222952927, "Suspected counterfeit product": 7.071822114470009, "Tachypnoea": 3.594470826053608, "Therapeutic product effect incomplete": 15.3924227825848, "Therapeutic response unexpected": 11.54869382384525, "Therapy interrupted": 3.2037059707587785, "Therapy non-responder": 13.807317754801812, "Therapy partial responder": 14.262059114873663, "Toothache": 2.2829275330481757, "Toxic epidermal necrolysis": 2.576332795993969, "Transfusion-related acute lung injury": 195.13001523224176, "Transfusion-related circulatory overload": 230.7709572705533}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/541.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/541.json
index e3c4f6c31b3..5ac12c1e543 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/541.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/541.json
@@ -1 +1 @@
-{"Abdominal distension ": 5.002028226268736, "Bronchitis ": 5.372261402599774, "Cellulitis ": 3.293885050386294, "Death ": 3.1450687884129183, "Device infusion issue ": 134.81785238934387, "Erythema ": 2.997586707780755, "Illness ": 3.7442010750574433, "Inappropriate schedule of product administration ": 3.5836123627091583, "Incorrect dose administered ": 4.456709770838998, "Infection ": 3.4340667064465413, "Infusion related reaction ": 3.3763105294911497, "Infusion site discharge ": 409.8161138455493, "Infusion site erythema ": 213.33950924423783, "Infusion site pain ": 200.52019454525885, "Infusion site pruritus ": 105.6526710566351, "Infusion site swelling ": 191.9980464667072, "Injection site erythema ": 3.963701915684325, "Intentional product use issue ": 2.0846086904484973, "Lower respiratory tract infection ": 3.640139125199566, "Meningitis aseptic ": 39.738901622563006, "Pneumonia ": 3.2412222490637514, "Product dose omission issue ": 2.6790262829050624, "Product storage error ": 8.240110990668715, "Product temperature excursion issue ": 205.86537416457296, "Respiratory tract infection ": 10.082867576944707, "Sinusitis ": 10.14392377118188, "Urinary tract infection ": 3.359981089821016}
\ No newline at end of file
+{"Abdominal abscess": 4.031100590227662, "Abscess": 6.809282414915288, "Acne": 3.0280996879267668, "Acute myocardial infarction": 2.0782178330116072, "Adverse drug reaction": 5.29476085376285, "Alanine aminotransferase abnormal": 3.995588615920731, "Amputation": 8.72426333525107, "Anal abscess": 4.176275151285838, "Anal fissure": 10.169972050073527, "Anal fistula": 26.325392107690316, "Anal incontinence": 3.465806971446582, "Animal bite": 11.04194052913834, "Ankylosing spondylitis": 11.309667062130446, "Anti-cyclic citrullinated peptide antibody": 11.589286023490637, "Arthritis": 5.591365302742274, "Arthritis bacterial": 5.979335821705668, "Arthritis infective": 5.917856987651562, "Arthrodesis": 8.700235070892633, "Arthropathy": 2.612836024360378, "Arthropod bite": 2.949295139401982, "Basal cell carcinoma": 2.110285828629564, "Bladder transitional cell carcinoma": 16.852078608984623, "Blood creatinine decreased": 5.088663338530874, "Blood iron decreased": 2.1214977221277405, "Bowel movement irregularity": 6.058854449025374, "Bursitis": 2.742845064147514, "C-reactive protein abnormal": 2.006925372147578, "C-reactive protein decreased": 33.98570402831981, "C-reactive protein increased": 2.7669065895181872, "Candida infection": 2.798674361910032, "Cardiac pacemaker insertion": 3.71327773196224, "Carpal tunnel syndrome": 3.2532401238341717, "Cataract": 2.679841297942496, "Cerebral venous sinus thrombosis": 2.3251700780101854, "Cervical vertebral fracture": 4.328709610487277, "Cholangitis sclerosing": 11.795799703317918, "Cholecystectomy": 2.647319857160583, "Chronic cutaneous lupus erythematosus": 21.323570868089508, "Clavicle fracture": 5.081659476452127, "Clostridium difficile infection": 2.879046603471997, "Coeliac disease": 2.6325244279893125, "Colectomy": 8.95675001293942, "Colitis": 3.546166370423343, "Colitis ulcerative": 11.73562119680784, "Colon cancer": 2.2499781799661105, "Contraindicated product administered": 2.3483631962487768, "Coronary artery 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"Gastrointestinal toxicity": 3.365072145680986, "General symptom": 10.789202509719487, "Glomerular filtration rate abnormal": 3.7057653826172894, "Glucose tolerance impaired": 6.596604427153548, "Grip strength decreased": 4.322304163807522, "Groin pain": 3.33066359190656, "Haematochezia": 2.981173264424042, "Hepatic fibrosis": 3.12431126169822, "Hepatic steatosis": 3.3410620984761707, "Hepatitis B": 2.1791827003331794, "Herpes simplex oesophagitis": 355.07134329475025, "Hidradenitis": 46.584990412848384, "Hodgkin's disease": 4.5711698335401305, "Hyperphagia": 16.165179724047775, "Hysterectomy": 2.7958462345681245, "Ileostomy": 15.434281493634153, "Immunodeficiency": 7.395190102517019, "Immunosuppression": 4.637544011122462, "Impaired quality of life": 7.132041644020717, "Impaired work ability": 2.789202680415823, "Infection": 2.611964933001313, "Inflammation": 5.166774507411562, "Inflammatory bowel disease": 6.680591347388483, "Inflammatory marker increased": 4.672471322094531, 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"Musculoskeletal stiffness": 3.569983453808026, "Myasthenia gravis": 2.330000292524389, "Neck pain": 2.4570532986957287, "Nephrolithiasis": 2.09872884213712, "Nerve compression": 5.137248728169712, "Nodule": 3.220964140887086, "Nonspecific reaction": 12.29965124554682, "Nystagmus": 2.1563249079890223, "Obstruction": 7.593318383881071, "Ophthalmoplegia": 5.881218698112993, "Oral herpes": 2.769306108257209, "Osteoarthritis": 6.089591043749673, "Pathogen resistance": 4.83612561579362, "Peripheral swelling": 2.488476437947718, "Pilonidal disease": 56.872705957459154, "Polyarthritis": 4.8508585010418095, "Polyp": 3.831192524620031, "Poor peripheral circulation": 2.224481445304534, "Poor venous access": 9.384039242687614, "Post procedural complication": 2.290166650847856, "Post procedural infection": 8.478065710577587, "Post-traumatic pain": 48.42026989994539, "Postoperative wound infection": 2.723031372099268, "Pouchitis": 39.47719949399934, "Procedural pain": 4.235908062788276, "Proctalgia": 3.0980058629307856, "Proctitis": 2.849794287046338, "Product contamination physical": 19.310051257051537, "Product label issue": 8.403708208447815, "Pseudomonas infection": 2.75240673640999, "Psoriasis": 13.135154330538048, "Psoriatic arthropathy": 9.25610222096472, "Pulmonary pain": 3.317677667088817, "Pulmonary tuberculosis": 4.383475672448549, "Pulmonary vasculitis": 12.091787183714588, "Purulent discharge": 4.03396463675811, "Pustular psoriasis": 4.93071027387284, "Pyoderma gangrenosum": 6.123685467308383, "Rectal haemorrhage": 3.059760340326412, "Red blood cell sedimentation rate decreased": 38.96867419144685, "Red blood cell sedimentation rate increased": 9.502806104864453, "Respiratory syncytial virus infection": 3.071752106648076, "Respiratory tract congestion": 2.643049216343457, "Retinal toxicity": 30.249776185190637, "Rheumatoid arthritis": 9.134133762900312, "Rheumatoid factor positive": 6.006983877141806, "Root canal infection": 247.9809353710986, "Rotator cuff syndrome": 2.513231398038109, "Sacroiliitis": 14.292555523912265, "Salt craving": 248.71273485385325, "Scar": 2.278185803948503, "Seasonal allergy": 2.467111749239992, "Sensitivity to weather change": 3.842116761482624, "Seronegative arthritis": 15.128219776676838, "Shoulder operation": 6.133072125324795, "Sinus congestion": 2.006779628758066, "Sinus disorder": 2.228984268349499, "Sinusitis": 2.5063964154649803, "Sinusitis bacterial": 17.94029116166011, "Sjogren's syndrome": 4.661747238142616, "Skin cancer": 3.05704990077892, "Skin induration": 3.67990042660381, "Skin lesion": 2.189345154213997, "Skin mass": 3.2314891267894343, "Skin plaque": 3.354314154454817, "Skin reaction": 2.000617164451952, "Small intestinal obstruction": 3.575171539071658, "Spinal osteoarthritis": 4.62800484409362, "Spinal stenosis": 2.0427819162657173, "Spondylitis": 6.445031853847921, "Squamous cell carcinoma": 3.0997302442422336, "Squamous cell carcinoma of skin": 2.466184976551076, "Stenosis": 11.830584861422118, "Steroid dependence": 31.50258602108472, "Stress": 4.301117244529364, "Subcutaneous abscess": 5.285094406043013, "Surgery": 2.3044968072563727, "Swollen joint count increased": 8.040641780030887, "Synovitis": 12.242521844973458, "Systemic lupus erythematosus": 2.346277825796239, "Tachyarrhythmia": 7.189093969818699, "Temperature regulation disorder": 4.016110599911016, "Tenosynovitis": 3.1616249765681133, "Thalassaemia minor": 198.03109718244352, "Therapeutic product effect decreased": 12.403050313452557, "Therapeutic product effect incomplete": 5.2591283705174, "Therapeutic response shortened": 17.25792024670772, "Therapy partial responder": 4.168359433284544, "Tooth abscess": 7.841078157166755, "Transfusion reaction": 27.55151702735323, "Treatment failure": 3.61279489807115, "Trismus": 2.299904390281895, "Tuberculosis": 5.358199747716487, "Type 1 diabetes mellitus": 2.6063099577434405, "Type 2 diabetes mellitus": 4.814065099344285, "Ulcer": 4.719838736723057, "Unevaluable event": 3.917841974056877, "Uterine polyp": 9.1013026752956, "Uveitis": 5.916080670120188, "Viral tonsillitis": 245.76751199863844, "Vitamin D decreased": 2.6120762560696664, "White matter lesion": 10.040674318241368, "Wound complication": 11.435098905172325, "Wound dehiscence": 6.317050251849163, "Wound secretion": 4.85127272462081, "Wrist deformity": 20.90761609703098}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/542.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/542.json
index 48a7c727368..c2760e453e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/542.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/542.json
@@ -1 +1 @@
-{"Fall ": 4.033610703738835}
\ No newline at end of file
+{"Agranulocytosis": 2.2458824067425622, "Anaemia": 13.81168275832488, "Blood alkaline phosphatase increased": 3.106180453629597, "Blood bilirubin increased": 2.9637077820045667, "Blood lactate dehydrogenase increased": 7.454170133962839, "Blood sodium decreased": 8.21096265461587, "Blood urea increased": 5.375157798213568, "Bone marrow failure": 8.994056512647528, "Death": 5.825803702001005, "Decreased appetite": 4.286254216876636, "Disease progression": 4.088221527901891, "Febrile neutropenia": 14.75578955889442, "Haematotoxicity": 19.74903657799025, "Haemoglobin decreased": 4.2356837408112336, "Ileus": 10.828623647493885, "Interstitial lung disease": 5.31336863781602, "Leukopenia": 11.89773106008094, "Myelosuppression": 5.49694849873427, "Neutropenia": 7.038621871041289, "Neutrophil count decreased": 37.82139309258236, "Pancytopenia": 14.407835973075754, "Platelet count decreased": 24.06033229321545, "Protein total decreased": 39.56100020244674, "Red blood cell count decreased": 59.5453019001828, "Sepsis": 2.5976700428449946, "Small cell lung cancer": 105.22367541660442, "Thrombocytopenia": 8.222343315194156, "White blood cell count decreased": 24.24588415432542}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/543.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/543.json
index 0b528d75b05..50de4986382 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/543.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/543.json
@@ -1 +1 @@
-{"Abdominal pain upper ": 19.7594841416916, "Adverse event ": 96.01779975622595, "Apparent death ": 3002.8779500427586, "Gastric haemorrhage ": 389.9155962150428, "Gastric perforation ": 2341.8356390871418, "Gastritis erosive ": 778.2955641308783, "Gastrointestinal disorder ": 45.21604268733434, "General physical health deterioration ": 41.74013679922363, "Stress ": 119.16129990853575}
\ No newline at end of file
+{"Acute kidney injury": 5.384028878342408, "Angioedema": 4.821075652509352, "Blood creatine phosphokinase increased": 2.109052229109457, "Blood creatinine increased": 4.936031143424768, "Blood pressure decreased": 2.1468993716663785, "Blood pressure fluctuation": 7.503337707575477, "Blood pressure increased": 4.319026351272246, "Cataract": 5.047155231959379, "Completed suicide": 4.547487303790689, "Eye pain": 4.479097198272771, "Hyperglycaemia": 2.5795252685950327, "Hyperkalaemia": 4.60540271997718, "Hypokalaemia": 26.44071193552828, "Hyponatraemia": 14.822155081241691, "Hypotension": 4.691254370862996, "Intentional overdose": 2.0235000204827176, "Liver function test abnormal": 3.499071064472354, "Oedema peripheral": 2.476032338555156, "Product substitution issue": 16.203726705119042, "Renal impairment": 5.410987786738501, "Restlessness": 2.075239952543037, "Stevens-Johnson syndrome": 5.435724155453702, "Suicide attempt": 2.6614860996521035, "Swelling face": 3.839674414283453, "Systemic lupus erythematosus": 4.660739266470458, "Therapeutic response unexpected": 4.561638438198443, "Toxicity to various agents": 3.388301594537451, "Urinary tract infection": 2.2699568972014603, "Vision blurred": 2.686706493226288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/544.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/544.json
index 3c7cf51a7a5..ca85e5cb8c8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/544.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/544.json
@@ -1 +1 @@
-{"Accident ": 2.571229126322253, "Alopecia ": 6.034025622932893, "Anaemia ": 2.866856742570888, "Anaemia macrocytic ": 3.4056776782367724, "Aphonia ": 2.112672352822748, "Aphthous ulcer ": 2.166572291530525, "Appetite disorder ": 3.0988391054693385, "Arthropod bite ": 4.026229544770969, "Back disorder ": 2.053451511423694, "Basophil count increased ": 9.281015349640894, "Basophil percentage increased ": 17.46430699825248, "Blood calcium decreased ": 3.067188052037176, "Blood calcium increased ": 2.0534482496794126, "Blood disorder ": 3.10317920404061, "Blood iron decreased ": 3.563610610790532, "Blood potassium decreased ": 2.882939020667273, "Blood test abnormal ": 9.42028648752632, "Body height decreased ": 5.219871967464576, "Body surface area decreased ": 133.49193267964904, "Body surface area increased ": 127.41102751754788, "Bone cancer ": 5.625118308725822, "Bone disorder ": 3.566690824939559, "Bone lesion ": 4.776382708544583, "Bone marrow disorder ": 2.78722446056423, "Bone pain ": 3.3183384413566097, "Brain fog ": 3.014784163604771, "Breast cancer metastatic ": 6.342310156859161, "Breast cancer recurrent ": 3.8238023274635182, "Breast cancer stage IV ": 24.077295070764603, "Breast conserving surgery ": 5.356533999489099, "Breast disorder ": 2.4400004914514275, "Breast haemorrhage ": 16.94664086586256, "Breast operation ": 17.298049151282374, "Cancer pain ": 23.03056015614105, "Carbohydrate antigen 15-3 increased ": 24.36812550013488, "Carbohydrate antigen 27.29 increased ": 90.97860162525856, "Carcinoembryonic antigen increased ": 7.34746573046643, "Cataract ": 3.2750642879210643, "Cellulitis ": 2.4487339498470786, "Cerebral disorder ": 2.451450997669994, "Chest injury ": 4.821448054000725, "Choking ": 2.0301566157253434, "Constipation ": 2.8393373713570105, "Cutaneous lupus erythematosus ": 3.2328293783195527, "Cystitis ": 2.1648941760714444, "Cytopenia ": 8.640406334935028, "Deafness ": 2.920530624708003, "Decreased appetite ": 2.2610390541484087, "Decreased immune responsiveness ": 49.93352861905284, "Dementia ": 4.1310356315150685, "Dementia Alzheimer's type ": 2.773054846962712, "Dental care ": 11.220936108878467, "Dental discomfort ": 6.220108921870515, "Dental operation ": 5.71507430599807, "Diverticulitis ": 2.331372146965253, "Dry eye ": 2.9500477398951688, "Dry skin ": 6.848193142772971, "Eating disorder ": 4.065972522334304, "Emotional disorder ": 2.572364353113036, "Endodontic procedure ": 5.627225351599845, "Enteritis infectious ": 4.492728947663778, "Epistaxis ": 2.229376098586111, "Eye operation ": 6.490944616717565, "Febrile neutropenia ": 2.5069781970912413, "Feeding disorder ": 2.907722490687205, "Femur fracture ": 2.66246101688211, "Food poisoning ": 2.4292271148369307, "Foreign body in throat ": 5.245087393472557, "Full blood count abnormal ": 15.27260410172254, "Full blood count decreased ": 42.48325290401619, "Gait inability ": 2.2766574761895844, "Gallbladder operation ": 4.232354761415636, "Gastric infection ": 3.961239749304833, "Gingival disorder ": 2.0561398557334174, "Gingival pain ": 2.440842156178432, "Granulocyte count decreased ": 2.099639522465786, "Haematocrit decreased ": 4.237997329274284, "Haematotoxicity ": 3.340843349312578, "Haemoglobin decreased ": 3.464622269002616, "Hair disorder ": 6.901600712864602, "Hair growth abnormal ": 2.8969949912489854, "Hair texture abnormal ": 6.1718156956636845, "Hepatic lesion ": 2.000698295339397, "Hip fracture ": 4.487625372662655, "Hip surgery ": 3.2873396020775782, "Hot flush ": 4.070469567484352, "Hyperchlorhydria ": 2.458552519735249, "Hypersomnia ": 2.2185289329387463, "Hypertransaminasaemia ": 2.3679751969131835, "Hypoacusis ": 3.868031664252529, "Hysterectomy ": 3.050273152921164, "Illness ": 4.036742672154752, "Immune system disorder ": 5.517148268561308, "Immunodeficiency ": 2.2790204096182807, "Immunosuppression ": 5.212985762838488, "Infection ": 2.1970828220862284, "Intentional dose omission ": 2.832569606483682, "Investigation abnormal ": 5.783308024553341, "Jaw disorder ": 4.293989566536973, "Joint injury ": 2.2942220190668263, "Kidney infection ": 3.701058777999565, "Knee operation ": 3.090937407224915, "Laboratory test abnormal ": 7.737323458994262, "Lacrimation increased ": 3.984079348091146, "Leukopenia ": 6.095799576866688, "Limb injury ": 2.7442242848153064, "Lip blister ": 2.017281019146413, "Lip dry ": 2.018537798798818, "Lip pain ": 2.188061624380058, "Localised infection ": 3.3460553154616264, "Loose tooth ": 2.644938277439671, "Lower limb fracture ": 2.649335710807593, "Lymphocyte count decreased ": 2.572321939252668, "Lymphocyte count increased ": 3.785180184443382, "Lymphocyte percentage increased ": 12.376931092724089, "Lymphoedema ": 8.07985345850302, "Macrocytosis ": 7.540550442395319, "Madarosis ": 12.718244721351205, "Malignant pleural effusion ": 4.226978430617154, "Mastectomy ": 11.27277707633053, "Mastitis ": 4.795460322981487, "Mean cell haemoglobin increased ": 15.138469951290771, "Mean cell volume increased ": 19.306710242500284, "Memory impairment ": 3.124955162588955, "Mental impairment ": 2.191403480274153, "Metastases to bone ": 3.5405607850667407, "Metastases to spine ": 2.542986041380823, "Monocyte count decreased ": 8.704475938106404, "Monocyte count increased ": 2.884459912449413, "Monocyte percentage increased ": 6.400424103006786, "Mucosal inflammation ": 3.0542357538811973, "Musculoskeletal chest pain ": 3.2021676715538043, "Nail discolouration ": 3.305925556801524, "Nail disorder ": 8.247312251240555, "Nasal disorder ": 2.0912241390637885, "Nasal dryness ": 2.674845603599179, "Nasopharyngitis ": 2.288907611738858, "Neoplasm progression ": 68.26536752826036, "Neoplasm recurrence ": 15.039361850301924, "Nerve injury ": 2.6269853037258817, "Neuropathy peripheral ": 3.80939649713573, "Neutropenia ": 22.491671207551526, "Neutrophil count abnormal ": 3.518592586697804, "Neutrophil count decreased ": 16.268960169871683, "Oesophageal pain ": 2.1298317227998886, "Oesophageal stenosis ": 2.4235391458587423, "Oestrogen receptor assay positive ": 13.605110566070923, "Onychoclasis ": 15.583683980199767, "Oophorectomy ": 16.828134281834593, "Oral disorder ": 2.2929451276594057, "Oral infection ": 5.228113791390726, "Oral mucosal blistering ": 2.5852205198454783, "Oral pain ": 4.754720436185472, "Oral surgery ": 10.91489074330277, "Osteomyelitis ": 2.646834346981601, "Osteonecrosis of jaw ": 8.663465993503198, "Ovarian disorder ": 7.080428342156689, "Paranasal sinus hypersecretion ": 5.720525304362393, "Pathological fracture ": 3.957199147952972, "Pharyngeal disorder ": 3.822846010394968, "Platelet count decreased ": 5.355804261632757, "Platelet disorder ": 3.723636835827567, "Pleural effusion ": 3.164173986143324, "Pneumonia ": 2.4666671724433, "Pneumonitis ": 2.468327104113717, "Poor quality product administered ": 3.111446403852923, "Pre-existing condition improved ": 2.1848773686945995, "Product administration interrupted ": 4.6872605400474265, "Product dispensing error ": 4.095536287614363, "Product dispensing issue ": 5.772013421315129, "Product dose omission in error ": 14.816397952362763, "Product dose omission issue ": 4.560029414065735, "Product packaging difficult to open ": 16.42254706027971, "Product prescribing error ": 2.093625124404104, "Product prescribing issue ": 2.314142591208772, "Product size issue ": 3.3666547380900558, "Product use complaint ": 2.382685744245473, "Product use issue ": 2.2085648386272427, "Pulmonary mass ": 2.1814186579031767, "Pulmonary oedema ": 3.798827063230996, "Pulmonary thrombosis ": 8.379666530052425, "Radiation injury ": 19.616821712125684, "Red blood cell count abnormal ": 14.157582683321062, "Red blood cell count decreased ": 16.87773232875127, "Red cell distribution width increased ": 7.306818359373613, "Scratch ": 2.134318822522298, "Second primary malignancy ": 30.318219119167768, "Sensitivity to weather change ": 2.2702795348853173, "Shoulder fracture ": 2.381525583225077, "Sinus disorder ": 2.835737815491773, "Spinal disorder ": 2.894286859712343, "Spinal fracture ": 3.102523817966909, "Spinal operation ": 3.0322231324572217, "Spinal pain ": 2.1381730449540424, "Stomatitis ": 7.54643731533004, "Stress ": 2.671666498681022, "Taste disorder ": 2.473688549528689, "Terminal state ": 2.163928710991041, "Thrombocytopenia ": 2.605992565160629, "Thrombosis ": 2.916409384188319, "Tongue blistering ": 2.3188982405938505, "Tongue disorder ": 2.721941127507206, "Tooth abscess ": 2.5033381256856058, "Tooth disorder ": 4.42049864003743, "Tooth extraction ": 6.649810531628682, "Tooth fracture ": 2.051550178106564, "Tooth infection ": 3.639243743902664, "Toothache ": 2.162672460436755, "Trichorrhexis ": 8.27499638243069, "Trigger finger ": 2.800801972186056, "Tumour haemorrhage ": 2.2090879581435483, "Tumour marker abnormal ": 30.67250128328673, "Tumour marker increased ": 34.73626356611721, "Tumour pain ": 9.453540647256586, "Upper limb fracture ": 3.9486453295592447, "Upper-airway cough syndrome ": 3.036887642197566, "Urinary tract infection ": 3.3060110375070635, "Vein disorder ": 2.638955868582172, "Vein rupture ": 8.878906713193357, "Vitamin B12 decreased ": 2.8129774346695293, "Vulvovaginal dryness ": 2.727969265397052, "Weight decreased ": 2.150379073574987, "Weight fluctuation ": 4.347649802845661, "White blood cell count abnormal ": 14.034120436953607, "White blood cell count decreased ": 20.23655126051729, "White blood cell disorder ": 7.523910379794159, "Wound complication ": 2.065868311439693, "Wound infection ": 2.320430899703708}
\ No newline at end of file
+{"Adrenal insufficiency": 15.245439406787762, "Adrenal suppression": 56.34668195666265, "Adrenocortical insufficiency acute": 33.57215169695287, "Angiopathy": 9.142110937224588, "Apnoea": 4.196350242297737, "Aspergillus infection": 4.03508640411214, "Asthmatic crisis": 2.59486931973495, "Auditory disorder": 7.789567972717974, "Bacteraemia": 2.658084220560053, "Blood bicarbonate decreased": 9.07703565732296, "Blood lactic acid increased": 3.504200060523153, "Blood pH decreased": 10.148701302954477, "Body temperature fluctuation": 9.094026154220138, "Bone disorder": 2.930371572002754, "Bronchiectasis": 7.162908448924911, "Burning sensation": 3.0969693038861887, "Caesarean section": 4.6666713983625865, "Calcinosis": 23.9243125100032, "Cardiomegaly": 2.5390179900667085, "Cataract": 2.132282217373119, "Central obesity": 26.30084357726834, "Cerebral disorder": 12.293685709605276, "Clonus": 7.571594507158554, "Cortisol decreased": 19.207637872764312, "Craniocerebral injury": 11.27233427161614, "Crepitations": 6.031389503242374, "Cushing's syndrome": 23.646301883744197, "Cushingoid": 6.186301484113043, "Decreased interest": 20.65144545125152, "Dermatitis": 2.194257795647756, "Dermatitis atopic": 6.322674944080609, "Dermatitis bullous": 2.773415192374344, "Device dislocation": 36.76049770910342, "Device malfunction": 6.385498762048218, "Disease recurrence": 3.0577490342394613, "Diverticulum": 3.6382542333226455, "Dizziness postural": 3.2811280889894068, "Dry skin": 2.198940002968361, "Dysuria": 2.4891874598136163, "Ear infection": 2.579186973061092, "Eczema": 5.522840295222628, "Electroencephalogram abnormal": 4.368647346545763, "Emotional disorder": 2.4748541453047777, "Erythema": 2.1208520477109283, "Exposure during pregnancy": 2.1776190232174337, "Feeling cold": 2.535180435375461, "Foetal death": 4.203265532128063, "Foetal growth restriction": 2.105101734585443, "Fungal infection": 2.469442753759983, "Gingival disorder": 21.50384544829572, "Growth retardation": 5.65537225485269, "Hip arthroplasty": 3.6720751501504094, "Hypercapnia": 10.323423269446415, "Hypercholesterolaemia": 2.2566574133524604, "Hyperventilation": 2.1366673032336387, "Hypoacusis": 2.475972254251155, "Hypomagnesaemia": 2.67415295277126, "Hypophosphataemia": 6.920905188139471, "Hypothalamic pituitary adrenal axis suppression": 96.50531063051272, "Inflammation": 2.042905407538512, "Knee arthroplasty": 4.4038466671475165, "Lethargy": 2.893575116257992, "Lip swelling": 2.218696826873717, "Lipase increased": 2.4438800141232124, "Live birth": 7.561978206375191, "Lung hyperinflation": 24.093150856118207, "Maternal exposure during breast feeding": 6.615894698342533, "Maternal exposure during pregnancy": 2.3154583639251487, "Medication error": 3.863950162006588, "Mobility decreased": 2.075615135630243, "Multiple organ dysfunction syndrome": 3.530654857521362, "Multiple-drug resistance": 4.785969055520449, "Muscle fatigue": 4.276158889589354, "Nerve compression": 15.210742969344835, "Neuralgia": 4.919729649132236, "Oral disorder": 9.219393402718625, "PCO2 increased": 29.482577194220813, "PO2 decreased": 19.89671380790012, "Pain of skin": 3.175219573664246, "Perfume sensitivity": 80.00122174490629, "Periarthritis": 5.089271158083681, "Perineal pain": 80.02663729094438, "Peripheral coldness": 4.130915360483504, "Peripheral venous disease": 4.440242135666392, "Pituitary tumour benign": 13.078093643284394, "Post procedural infection": 7.488752269004917, "Premature baby": 3.5104313441560904, "Premature delivery": 6.506040444871801, "Premature labour": 4.044609075760741, "Preterm premature rupture of membranes": 74.16520319488252, "Quality of life decreased": 2.325508704833434, "Radiculopathy": 8.930861243177445, "Respiratory acidosis": 7.050838417565642, "Respiratory arrest": 2.0903741293829423, "Respiratory disorder": 3.568656818210146, "Respiratory rate increased": 3.853196918532487, "Scab": 4.115729441891854, "Seasonal allergy": 2.770592022300437, "Secondary adrenocortical insufficiency": 9.399777387830484, "Sensitive skin": 3.321162176162777, "Sinus headache": 4.154984131077244, "Skin atrophy": 19.17172830135153, "Skin burning sensation": 14.342196795249595, "Skin exfoliation": 10.491159128178236, "Skin fissures": 4.395365946408305, "Skin haemorrhage": 2.697941298279648, "Skin hyperpigmentation": 10.445511434852934, "Skin infection": 11.534978934134068, "Skin irritation": 7.351212524133766, "Skin lesion": 3.211876117406701, "Skin swelling": 8.634549363730603, "Skin warm": 2.837085925833804, "Skin weeping": 213.60008751670057, "Skin wrinkling": 37.797468495424965, "Sleep disorder due to a general medical condition": 2.8873273515233966, "Steroid withdrawal syndrome": 332.72717613374505, "Temperature regulation disorder": 8.880705371697477, "Tendonitis": 3.44702652238286, "Thyrotoxic crisis": 15.281199487922304, "Topical steroid withdrawal reaction": 166.20119662856823, "Toxic epidermal necrolysis": 2.70531269600856, "Urinary tract disorder": 18.617661348648635, "Wheezing": 2.591823319680829}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/545.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/545.json
index ea4d8ea6c58..de69163b360 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/545.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/545.json
@@ -1 +1 @@
-{"Aspergillus infection ": 55.08954281720174, "Atrial fibrillation ": 10.00764399171014, "Blood lactate dehydrogenase increased ": 11.660909976688318, "Bronchopulmonary aspergillosis ": 20.694792117955508, "Cerebral aspergillosis ": 287.7403297789392, "Chronic lymphocytic leukaemia ": 316.67272627766965, "Chronic lymphocytic leukaemia recurrent ": 753.4167143014894, "Cytopenia ": 16.70377268500021, "Disease progression ": 16.790761862684313, "Drug interaction ": 3.371357128086994, "Drug resistance ": 8.485543119963147, "Febrile neutropenia ": 6.777115586950506, "Haemorrhage ": 4.512287200584412, "Infection ": 5.288100759325498, "Mantle cell lymphoma recurrent ": 455.5528273194338, "Neutropenia ": 6.134017951018556, "Neutrophil count decreased ": 3.01895934381053, "Off label use ": 3.158360871949148, "Pancytopenia ": 3.5397316369364558, "Platelet count decreased ": 3.817278220246769, "Progressive multifocal leukoencephalopathy ": 38.77745130906629, "Rash maculo-papular ": 3.65299281642972, "Splenomegaly ": 14.468967682550687, "Therapeutic product effect incomplete ": 5.515691145785869, "Therapy partial responder ": 25.24757006552831, "Thrombocytopenia ": 3.5338274272083177, "Treatment failure ": 2.6763459800547627, "Tumour lysis syndrome ": 31.630603538295382}
\ No newline at end of file
+{"Acute kidney injury": 20.92162756123594, "Hypercalcaemia": 408.7547512422973, "Hypervitaminosis": 12004.371426589903, "Intentional product misuse": 32.936759697651475, "Off label use": 5.461215161022811}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/546.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/546.json
index 91a88535538..6902fb45d7e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/546.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/546.json
@@ -1 +1 @@
-{"Abdominal tenderness ": 3.421873907536314, "Accidental exposure to product by child ": 2.044057906214277, "Accidental overdose ": 3.704540287481164, "Accidental poisoning ": 14.791116197444202, "Acidosis ": 7.098283005252054, "Acute generalised exanthematous pustulosis ": 5.515148025482381, "Acute hepatic failure ": 5.215297166348974, "Acute kidney injury ": 4.4055953412739015, "Acute respiratory distress syndrome ": 2.3897424803225733, "Agranulocytosis ": 3.023433015496555, "Akinesia ": 3.973665210715577, "Alcohol poisoning ": 3.741636567455613, "Allergy to animal ": 9.204938023619995, "Anaphylactic reaction ": 2.0974637126821314, "Angioedema ": 3.508300677439365, "Angular cheilitis ": 8.013172984045115, "Anuria ": 7.300396179883529, "Apnoea ": 3.643004603410384, "Apraxia ": 5.189039386941863, "Areflexia ": 3.518931992257468, "Aspiration ": 4.556899581465086, "Atelectasis ": 5.642420036713486, "Atrial septal defect ": 3.871928387731611, "Bile acids increased ": 61.6138247137884, "Blood bicarbonate decreased ": 6.4731692348201335, "Blood lactic acid increased ": 2.179345727958625, "Blood pH decreased ": 8.48137088452831, "Blood pH increased ": 53.68429781821969, "Blood urea increased ": 3.1792103723705267, "Brain death ": 5.082746119840254, "Brain injury ": 3.340828773615842, "Brain oedema ": 3.64743729290516, "Bronchial hyperreactivity ": 5.416079253761132, "Bronchial wall thickening ": 6.947162610014593, "Bronchitis chronic ": 3.597295329366199, "Cardiac arrest ": 2.560417477220527, "Cardio-respiratory arrest ": 6.760083834301645, "Cardiomegaly ": 2.164930251145773, "Central nervous system lesion ": 2.3206654160323907, "Cleft lip ": 10.142332201267935, "Cleft lip and palate ": 10.523635804757848, "Cleft palate ": 6.91740063532181, "Clonus ": 8.157182332833603, "Clostridium difficile infection ": 2.947251327698933, "Coagulopathy ": 2.2098481279247677, "Colitis ischaemic ": 2.4523218880520417, "Colitis microscopic ": 2.421737694377692, "Coma ": 3.6888094389882102, "Coma scale abnormal ": 6.56315368061976, "Completed suicide ": 17.97686418253335, "Congenital central nervous system anomaly ": 10.501102855375102, "Congenital musculoskeletal disorder ": 13.689689989294829, "Conjunctival hyperaemia ": 2.1056854367274265, "Cross sensitivity reaction ": 12.554721648855711, "Depressed level of consciousness ": 2.908909606249489, "Dermatitis exfoliative ": 3.098039465898974, "Dermatitis exfoliative generalised ": 2.401161443636788, "Device adhesion issue ": 29.044063949630686, "Device dislocation ": 14.15615731070101, "Device maintenance issue ": 745.8541047103722, "Device malfunction ": 2.5537336263098043, "Device power source issue ": 62.91403230198443, "Diastolic dysfunction ": 4.452926381456371, "Disease complication ": 4.432109074221251, "Drug abuse ": 3.329767673530079, "Drug dose titration not performed ": 12.8503836098202, "Drug eruption ": 2.0120722322588747, "Drug hypersensitivity ": 3.204526833778009, "Drug interaction ": 3.3097437045501445, "Drug screen positive ": 4.328366632475922, "Drug-induced liver injury ": 2.5447539340758816, "Duodenal ulcer ": 3.2581955401523253, "Duodenal ulcer haemorrhage ": 3.7089857890137634, "Electrocardiogram QRS complex prolonged ": 4.561890829333579, "Electrocardiogram QT prolonged ": 2.0300663838612167, "Electrocardiogram ST segment elevation ": 6.121215868968591, "Electrocardiogram abnormal ": 2.0865737765901438, "Emergency care ": 7.789073029268174, "Endometritis ": 36.862718427194565, "Environmental exposure ": 30.363655225139127, "Epidermal necrosis ": 8.210015589831482, "Erection increased ": 2.044133451429554, "Erythema multiforme ": 2.550843880225915, "Escherichia infection ": 4.692696996042766, "Eustachian tube dysfunction ": 18.06175415487636, "Female sterilisation ": 49.60117970772164, "Fine motor skill dysfunction ": 13.470464024160124, "Fixed eruption ": 3.09152143804726, "Flushing ": 2.116595295439533, "Gastric ulcer ": 3.9394986871177498, "Gastric ulcer haemorrhage ": 3.7354745245198737, "Gastritis erosive ": 2.544856480472044, "Gastrointestinal erosion ": 16.06182916324016, "Gastrointestinal haemorrhage ": 2.502131960766863, "Gastrointestinal inflammation ": 3.836057073915208, "Gastrointestinal sounds abnormal ": 5.901962992254547, "Glomerulonephritis membranous ": 7.458796376711299, "Grip strength decreased ": 6.159766234808938, "Haematemesis ": 3.165175977949407, "Haemodynamic instability ": 10.237646227088598, "Heart disease congenital ": 2.90783747424673, "Heart valve incompetence ": 7.847442260438244, "Hepatic failure ": 2.559207143884576, "Hepatic necrosis ": 6.66729557090834, "Hepatic steatosis ": 2.028187761763912, "Hepatitis cholestatic ": 2.3294116004471594, "Hepatitis toxic ": 2.321636507960174, "Hepatomegaly ": 3.1214779623115354, "Hepatosplenomegaly ": 2.703860227640599, "Holoprosencephaly ": 76.30012311567708, "Hyperkalaemia ": 2.5382969068128, "Hyperlactacidaemia ": 24.53415452523343, "Hyperreflexia ": 6.08559108966874, "Hypertonia ": 3.205743353596611, "Hypoalbuminaemia ": 3.128634439856203, "Hypochromic anaemia ": 7.843914610653111, "Hypopnoea ": 3.704401208047511, "Hypotension ": 2.1558033066021616, "Ileal perforation ": 16.457301471061623, "Inadequate analgesia ": 6.001305690065143, "Incorrect drug administration rate ": 18.919630755593754, "Incorrect product administration duration ": 2.20232104615282, "Infusion site discharge ": 17.220507142965946, "Infusion site discomfort ": 86.92604237483933, "Infusion site erythema ": 11.357535975605902, "Infusion site induration ": 68.49313046470938, "Infusion site irritation ": 29.044063949630686, "Infusion site pain ": 8.819957091522008, "Infusion site pruritus ": 8.312179719830008, "Infusion site swelling ": 15.730499965745548, "Intentional overdose ": 15.475397069824515, "Intentional product misuse ": 3.105478247839591, "Intervertebral disc disorder ": 4.621827501322883, "Intervertebral disc protrusion ": 2.270474365814132, "Ischaemia ": 2.380382687382895, "Kidney malformation ": 25.27663583011697, "Kounis syndrome ": 11.877066658304782, "Lactic acidosis ": 2.586924139039233, "Latent tuberculosis ": 13.153736572005554, "Leukocytosis ": 2.556335006828665, "Lip oedema ": 3.4243751666264832, "Liver injury ": 3.16786042811094, "Lower gastrointestinal haemorrhage ": 2.560607459385219, "Lung infiltration ": 2.066134980560748, "Major depression ": 2.253603958169095, "Maternal exposure timing unspecified ": 3.572631583992928, "Mean cell haemoglobin concentration decreased ": 10.572978677337328, "Medication error ": 4.136007331880804, "Medication overuse headache ": 38.72505589940975, "Mental status changes ": 2.602545099966308, "Metabolic acidosis ": 8.926399798142526, "Methaemoglobinaemia ": 7.733565513227944, "Microcephaly ": 10.311142660845665, "Micturition frequency decreased ": 47.07804721196963, "Miosis ": 2.683210750961254, "Mitochondrial toxicity ": 6.304984210756544, "Mucosal disorder ": 5.740734703305691, "Multiple organ dysfunction syndrome ": 2.3871455800737422, "Muscle spasticity ": 3.662268482713934, "Mydriasis ": 2.57348349358205, "Nasal dryness ": 5.95751326992526, "Nasal polyps ": 3.657189395413015, "Nerve compression ": 7.590653751468527, "Nikolsky's sign ": 7.656267664893967, "Normal newborn ": 2.9946487638060435, "Nystagmus ": 2.1040351789282403, "Obstructive airways disorder ": 2.25409525695472, "Oesophagitis ": 2.7239424092858573, "Oligoarthritis ": 45.39573188822148, "Oliguria ": 3.4213792468862194, "Oral mucosa erosion ": 3.9831365514475183, "Overdose ": 6.146872504657533, "Patent ductus arteriosus ": 7.5524229690021, "Peptic ulcer ": 4.539264714386686, "Periorbital oedema ": 3.1914461391077844, "Poisoning ": 4.962939752374636, "Poisoning deliberate ": 3.323374485896906, "Polyarthritis ": 2.2911146316362787, "Post-traumatic stress disorder ": 2.620573818334706, "Potentiating drug interaction ": 2.1043027363369298, "Product administration interrupted ": 15.276899283236482, "Pseudomonal sepsis ": 6.352531771174996, "Pseudomonas infection ": 3.1410134279904565, "Pulseless electrical activity ": 5.7802075477885255, "Purulent discharge ": 10.35079442418304, "Renal tubular acidosis ": 9.599299729202498, "Renal tubular necrosis ": 4.597349646826273, "Respiratory acidosis ": 4.94548005105974, "Respiratory arrest ": 4.829623987025287, "Respiratory rate decreased ": 3.9286644171193807, "Respiratory symptom ": 4.275672549454443, "Retching ": 3.0653927796386777, "Retinopathy ": 2.356505856554259, "Right atrial dilatation ": 68.35155925657848, "Right ventricular dilatation ": 33.850797699135974, "Right ventricular failure ": 2.7356591029030284, "Sacral pain ": 9.559130714319048, "Self-medication ": 9.622286655536966, "Serotonin syndrome ": 3.994458242259347, "Shock ": 4.626736044374078, "Shock haemorrhagic ": 2.2720273099398463, "Sinus bradycardia ": 2.4331116040741114, "Sinus tachycardia ": 2.717644410841382, "Skin laceration ": 4.167067591809862, "Skin swelling ": 3.0143620528474298, "Slow response to stimuli ": 3.305553509426986, "Somnolence ": 2.5205927263707903, "Sopor ": 4.6808137112386605, "Spirometry abnormal ": 21.02187982863005, "Staphylococcal sepsis ": 2.5557077354332383, "Stevens-Johnson syndrome ": 7.2422166461939534, "Stupor ": 4.001873510360035, "Substance abuse ": 2.411940675954169, "Suicide attempt ": 12.69977664635386, "Superinfection ": 9.612616255094716, "Superior mesenteric artery syndrome ": 72.58110008207089, "Suspected suicide ": 47.059842522309374, "Synovial cyst ": 5.28546708989836, "Systolic dysfunction ": 31.149638060258376, "Therapeutic product effect increased ": 4.980268648153829, "Throat tightness ": 2.0623994910531724, "Tongue oedema ": 2.673700126692938, "Toxic epidermal necrolysis ": 8.540315390374037, "Toxicity to various agents ": 12.278529284242463, "Tracheobronchitis ": 25.983639904427555, "Transposition of the great vessels ": 15.19842883217773, "Tricuspid valve incompetence ": 3.992271148059829, "Tubulointerstitial nephritis ": 4.049356413148567, "Type IV hypersensitivity reaction ": 4.558801500318839, "Unresponsive to stimuli ": 3.501804982344113, "Upper gastrointestinal haemorrhage ": 4.404948008030238, "Upper respiratory tract infection ": 2.284212370149188, "Ventricular septal defect ": 4.285084760815094, "Weight fluctuation ": 3.5382713112032005}
\ No newline at end of file
+{"Acute myeloid leukaemia": 30.41008111356076, "Anaemia": 2.7775273851548388, "Bone pain": 8.953866926559531, "Haemoglobin decreased": 5.15317163087806, "Platelet count increased": 58.28767027844895, "Splenomegaly": 48.70300139290743, "Thrombocytopenia": 2.288417505279981, "Weight increased": 3.028125320974097}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/547.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/547.json
index 852f54e16d0..2da83c08d84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/547.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/547.json
@@ -1 +1 @@
-{"Blood glucose increased ": 4.906519065630417, "Diarrhoea ": 2.459795177689464, "Glycosylated haemoglobin increased ": 35.549503557834065, "Pancreatitis acute ": 23.105299434417457}
\ No newline at end of file
+{"Abdominal distension": 4.99734977636592, "Bronchitis": 5.366916235002793, "Cellulitis": 3.290806022163914, "Death": 3.142124104690684, "Device infusion issue": 134.69183638673329, "Erythema": 2.994752042432056, "Illness": 3.7406992952198186, "Inappropriate schedule of product administration": 3.580260571462664, "Incorrect dose administered": 4.452542585374337, "Infection": 3.43085508085905, "Infusion related reaction": 3.3731539142298588, "Infusion site discharge": 409.4329683230082, "Infusion site erythema": 213.1398935689801, "Infusion site pain": 200.33254763251284, "Infusion site pruritus": 105.55391116455054, "Infusion site swelling": 191.81846317545907, "Injection site erythema": 3.9599937984408697, "Intentional product use issue": 2.082660150499248, "Lower respiratory tract infection": 3.636736275162868, "Meningitis aseptic": 39.70174060372521, "Pneumonia": 3.2381887397248224, "Product dose omission issue": 2.6765209506750827, "Product storage error": 8.232407696735963, "Product temperature excursion issue": 205.672933005972, "Respiratory tract infection": 10.073441185151372, "Sinusitis": 10.134434710573505, "Urinary tract infection": 3.356838952629091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/548.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/548.json
index db241cda5d9..0d7ceefffd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/548.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/548.json
@@ -1 +1 @@
-{"Angioedema ": 98.69102282093216, "Drug ineffective ": 5.100627621479056, "Hereditary angioedema ": 148.55685883911383, "Off label use ": 6.079907390989413, "Therapy non-responder ": 77.49263385000029}
\ No newline at end of file
+{"Fall": 4.033507316441314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/549.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/549.json
index c9ed0e8fea4..16a7f24c27f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/549.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/549.json
@@ -1 +1 @@
-{"Accelerated hypertension ": 46.27348328858969, "Acute coronary syndrome ": 7.110595663817508, "Acute lymphocytic leukaemia ": 69.15736258283168, "Acute lymphocytic leukaemia recurrent ": 126.7784429543712, "Acute myeloid leukaemia ": 2.062949410630812, "Acute myocardial infarction ": 7.349228006838453, "Allogenic stem cell transplantation ": 129.94614167075676, "Amylase increased ": 12.601941774524814, "Angina pectoris ": 2.5644106512476155, "Angina unstable ": 7.074902856258915, "Angiopathy ": 9.050060055837887, "Arterial occlusive disease ": 6.678339062934668, "Arteriosclerosis ": 6.599810202144397, "Arteriosclerosis coronary artery ": 4.056785561356703, "Atrial fibrillation ": 5.980738636145268, "Benign prostatic hyperplasia ": 4.691031022613292, "Blast cell crisis ": 292.1844386071012, "Blast crisis in myelogenous leukaemia ": 230.3105141951547, "Blindness unilateral ": 5.637633234211379, "Bone marrow failure ": 9.445390356738072, "Bone marrow transplant ": 40.83326897485544, "Bone pain ": 2.137808468907818, "Cardiac disorder ": 2.729452683090871, "Cardiac failure ": 5.098870178541138, "Cardiac failure acute ": 5.71769684477199, "Cardiomyopathy ": 3.5179272264288315, "Cardiotoxicity ": 4.4571784064512965, "Cardiovascular disorder ": 2.010681025695614, "Carotid arteriosclerosis ": 47.80376620813438, "Carotid artery stenosis ": 18.05575825649166, "Central nervous system leukaemia ": 159.99395438148198, "Cerebral artery stenosis ": 60.35980947481789, "Cerebral infarction ": 10.697099509547677, "Cerebral ischaemia ": 11.802743506450035, "Cerebrovascular accident ": 3.155666396707232, "Chemotherapy ": 14.359773184809605, "Chronic myeloid leukaemia ": 233.67049887803984, "Chronic myeloid leukaemia recurrent ": 367.26038042018, "Chronic myeloid leukaemia transformation ": 388.9019820992351, "Constipation ": 2.2392532053641574, "Coronary artery disease ": 6.018269049740005, "Coronary artery occlusion ": 4.181051839897023, "Coronary artery stenosis ": 28.538648969253117, "Cytogenetic analysis abnormal ": 19.693262216928247, "Cytopenia ": 21.968000783436064, "Death ": 3.7045437915291592, "Dermatitis exfoliative ": 16.309643829841363, "Disease complication ": 52.22913201027892, "Disease progression ": 3.887507361715729, "Drug resistance ": 2.6884976361881665, "Dry eye ": 3.6277618961705658, "Dry skin ": 8.639024360005838, "Ejection fraction decreased ": 4.9799410910838615, "Erectile dysfunction ": 5.06324363834545, "Exfoliative rash ": 8.586620657294072, "Febrile neutropenia ": 2.08746355379326, "Full blood count abnormal ": 2.176171772150969, "Full blood count decreased ": 3.9702374987291673, "Graft versus host disease ": 14.359605768883863, "Graft versus host disease in gastrointestinal tract ": 12.296544679845432, "Graft versus host disease in skin ": 27.43963679183444, "Haematocrit decreased ": 2.0211491628069385, "Haematotoxicity ": 12.952161655373692, "Hepatic failure ": 2.4449472374071406, "Hepatomegaly ": 2.1754795957608533, "Hepatotoxicity ": 8.42043415909153, "Hyperlipidaemia ": 2.1600304147834417, "Hypertension ": 4.439337080160114, "Hypertensive crisis ": 2.9854202902178293, "Hypertransaminasaemia ": 2.419927285511357, "Hypertriglyceridaemia ": 5.53918065904896, "Ichthyosis ": 224.17622711282465, "Ichthyosis acquired ": 216.95484361890703, "Infection ": 2.499938531406007, "Intermittent claudication ": 18.31691825185636, "Ischaemic stroke ": 9.488444658453872, "Leukaemia recurrent ": 31.68209624846668, "Leukocytosis ": 5.77165108887904, "Lipase increased ": 22.64525056272141, "Liver disorder ": 2.3031826408148737, "Liver function test increased ": 2.1667793031086, "Lymphocyte count decreased ": 2.385453769951053, "Mitral valve incompetence ": 4.1329524260223565, "Moyamoya disease ": 138.05836805067898, "Multiple organ dysfunction syndrome ": 2.38448957811382, "Myocardial infarction ": 3.066776604543855, "Myocardial ischaemia ": 6.990298694124772, "Neoplasm progression ": 20.95868142075205, "Neutropenia ": 2.2872187422178123, "No adverse event ": 2.43393812076235, "Off label use ": 3.880959680170221, "Pancreatic enzymes increased ": 13.177115422234298, "Pancreatitis ": 11.03762090090398, "Pancreatitis acute ": 5.193429312729352, "Pancytopenia ": 5.2916260186285, "Pericardial effusion ": 7.548719133276303, "Peripheral arterial occlusive disease ": 69.0623561839334, "Peripheral artery occlusion ": 12.879366070197138, "Peripheral artery stenosis ": 62.84336830361444, "Peripheral artery thrombosis ": 11.320424895315822, "Peripheral ischaemia ": 6.444370132216057, "Peripheral vascular disorder ": 4.207833105397713, "Philadelphia chromosome positive ": 93.7088246239684, "Philadelphia positive acute lymphocytic leukaemia ": 2288.780376911525, "Pityriasis rubra pilaris ": 53.93698520196627, "Platelet count abnormal ": 9.54351824708954, "Platelet count decreased ": 3.3027509225960663, "Pleural effusion ": 5.522035925912177, "Pneumonia ": 2.5469017214902885, "Pneumonia fungal ": 11.280808610512429, "Posterior reversible encephalopathy syndrome ": 5.8027476188123925, "Prinzmetal angina ": 34.87955655555459, "Product administered to patient of inappropriate age ": 15.700536603397218, "Pulmonary arterial hypertension ": 2.6699524652904234, "Pulmonary hypertension ": 4.181125461880895, "Red blood cell count decreased ": 2.3439505318834817, "Renal artery stenosis ": 64.84892343925344, "Retinal artery occlusion ": 7.683465024856064, "SARS-CoV-2 test positive ": 2.3584602267752177, "Scleroderma ": 9.602887915914474, "Sepsis ": 3.915848959366692, "Septic shock ": 6.230567785036587, "Skin exfoliation ": 6.776978661121519, "Skin lesion ": 2.024141604145083, "Skin toxicity ": 5.531173261438314, "Splenomegaly ": 2.951571122237291, "Stem cell transplant ": 80.01820927072826, "Sudden death ": 3.120851558584854, "Supraventricular tachycardia ": 2.224836690995568, "Therapeutic response decreased ": 2.0393038060943285, "Therapy non-responder ": 6.667315586010314, "Therapy partial responder ": 5.7934551053142505, "Thrombocytopenia ": 5.37349346706525, "Thrombotic microangiopathy ": 2.9541735766336026, "Transaminases increased ": 3.228045883148847, "Transient ischaemic attack ": 3.4443135580174005, "Transplant ": 65.54273089259819, "Treatment noncompliance ": 4.464177811067646, "Tumour marker increased ": 6.6734482241142175, "Unevaluable event ": 3.4328042221818205, "Vascular occlusion ": 12.789059565982903, "Venoocclusive liver disease ": 6.92449043178623, "Ventricular hypokinesia ": 6.815515388489292, "White blood cell count increased ": 2.877764765817604}
\ No newline at end of file
+{"Abdominal pain upper": 19.7594841416916, "Adverse event": 96.01779975622595, "Apparent death": 3002.8779500427586, "Gastric haemorrhage": 389.9155962150428, "Gastric perforation": 2341.8356390871418, "Gastritis erosive": 777.4529183729293, "Gastrointestinal disorder": 45.2146191549812, "General physical health deterioration": 41.74013679922363, "Stress": 119.16129990853575}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/55.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/55.json
index fec110e1891..b249597f13d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/55.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/55.json
@@ -1 +1 @@
-{"Hypersensitivity ": 11.663667858783253, "Limb injury ": 154.76060111989247, "Throat irritation ": 69.15917243321545}
\ No newline at end of file
+{"Abdominal distension": 2.357130840705633, "Alanine aminotransferase increased": 2.0029074851168747, "Amnesia": 2.722934579715965, "Aspartate aminotransferase increased": 2.28943919081107, "Coma": 2.2575438490669297, "Completed suicide": 4.259953852420468, "Depression": 2.4672795991243306, "Diabetes mellitus": 2.733659929445376, "Drug hypersensitivity": 3.0030386377431832, "Drug interaction": 4.139369269879214, "Exposure during pregnancy": 2.3168431560993987, "Hyperglycaemia": 2.932935963249306, "Hypersensitivity": 2.4495782522228144, "Intentional overdose": 2.10938882077663, "Intentional product misuse": 2.113627040119439, "Multiple organ dysfunction syndrome": 5.4626420270326665, "Pancytopenia": 2.192959408731116, "Stevens-Johnson syndrome": 4.412685173382017, "Suicidal ideation": 2.0736348445088155, "Suicide attempt": 3.4435101199441016, "Toxicity to various agents": 3.397317101549877, "Unevaluable event": 12.077456970166384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/550.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/550.json
index b25d5a9d93d..8794290f00b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/550.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/550.json
@@ -1 +1 @@
-{"Hyperglycaemic hyperosmolar nonketotic syndrome ": 2439.3512547825017}
\ No newline at end of file
+{"Accident": 2.570859978143032, "Alopecia": 6.033159060952129, "Anaemia": 2.866445045332925, "Anaemia macrocytic": 3.405188735784974, "Aphonia": 2.112369036849913, "Aphthous ulcer": 2.1662612334665137, "Appetite disorder": 3.0983942083397005, "Arthropod bite": 4.025651508926505, "Back disorder": 2.053156699461502, "Basophil count increased": 9.279682911532085, "Basophil percentage increased": 17.461799739212235, "Blood calcium decreased": 3.066747693101661, "Blood calcium increased": 2.0531534403148566, "Blood disorder": 3.102733683807813, "Blood iron decreased": 3.56309898436274, "Blood potassium decreased": 2.882525104247077, "Blood test abnormal": 9.418933937950497, "Body height decreased": 5.219122545171883, "Body surface area decreased": 133.4727678337479, "Body surface area increased": 127.39273568663631, "Bone cancer": 5.624310722418854, "Bone disorder": 3.5661787416609565, "Bone lesion": 4.775696975133128, "Bone marrow disorder": 2.7868243082948125, "Bone pain": 3.317861978863516, "Brain fog": 3.014351312471477, "Breast cancer metastatic": 6.34139955419433, "Breast cancer recurrent": 3.823253353087021, "Breast cancer stage IV": 24.073838371410297, "Breast conserving surgery": 5.3557649830472815, "Breast disorder": 2.439650192806177, "Breast haemorrhage": 16.944207912524966, "Breast operation": 17.295565731531614, "Cancer pain": 23.027253589852585, "Carbohydrate antigen 15-3 increased": 24.36462699484826, "Carbohydrate antigen 27.29 increased": 90.9655402312428, "Carcinoembryonic antigen increased": 7.346410867174251, "Cataract": 3.2745940505915128, "Cellulitis": 2.448382365084096, "Cerebral disorder": 2.451099046714246, "Chest injury": 4.820755855398773, "Choking": 2.029865143913375, "Constipation": 2.838929655158404, "Cutaneous lupus erythematosus": 3.232365257244432, "Cystitis": 2.1645833552915485, "Cytopenia": 8.632038655718587, "Deafness": 2.920111301956074, "Decreased appetite": 2.2606922237762874, "Decreased immune responsiveness": 49.92635885832409, "Dementia": 4.13044250844346, "Dementia Alzheimer's type": 2.7726567223217184, "Dental care": 11.219325168304538, "Dental discomfort": 6.219215929886529, "Dental operation": 5.714253820543724, "Diverticulitis": 2.331037422962926, "Dry eye": 2.9496241876286198, "Dry skin": 6.865324103264642, "Eating disorder": 4.065388748878825, "Emotional disorder": 2.5719950340618736, "Endodontic procedure": 5.626417478185196, "Enteritis infectious": 4.492083945773895, "Epistaxis": 2.229055988206126, "Eye operation": 6.490012724115688, "Febrile neutropenia": 2.506618236328081, "Feeding disorder": 2.9073050177231123, "Femur fracture": 2.662078761243323, "Food poisoning": 2.4288783618953502, "Foreign body in throat": 5.244334363673514, "Full blood count abnormal": 15.270411036050346, "Full blood count decreased": 42.477152671963, "Gait inability": 2.27633059772132, "Gallbladder operation": 4.231747137504277, "Gastric infection": 3.960671050321068, "Gingival disorder": 2.0558446648102597, "Gingival pain": 2.4404917280363727, "Granulocyte count decreased": 2.099338082875037, "Haematocrit decreased": 4.237388852170649, "Haematotoxicity": 3.3403637038813287, "Haemoglobin decreased": 3.4641247751401054, "Hair disorder": 6.900609871191678, "Hair growth abnormal": 2.8965790767574564, "Hair texture abnormal": 6.170929614891883, "Hepatic lesion": 2.000411061606712, "Hip fracture": 4.486981048415546, "Hip surgery": 3.28686764811359, "Hot flush": 4.069885096739005, "Hyperchlorhydria": 2.458199557668983, "Hypersomnia": 2.218210411178181, "Hypertransaminasaemia": 2.3676352241388594, "Hypoacusis": 3.867145519346536, "Hysterectomy": 3.049835233478537, "Illness": 4.036163018993732, "Immune system disorder": 5.516356141983105, "Immunodeficiency": 2.278693209586436, "Immunosuppression": 5.212237334347816, "Infection": 2.196767350779605, "Intentional dose omission": 2.8321629379923974, "Investigation abnormal": 5.782477739868759, "Jaw disorder": 4.293373092637439, "Joint injury": 2.2938926367442845, "Kidney infection": 3.700527406941676, "Knee operation": 3.090493648508134, "Laboratory test abnormal": 7.736212562969245, "Lacrimation increased": 3.983507325439702, "Leukopenia": 6.094136083837867, "Limb injury": 2.7438302884010595, "Lip blister": 2.016991407013564, "Lip dry": 2.018248002760806, "Lip pain": 2.187747492887272, "Localised infection": 3.3455749149455616, "Loose tooth": 2.644558555850101, "Lower limb fracture": 2.648955341056605, "Lymphocyte count decreased": 2.5719526298019595, "Lymphocyte count increased": 3.784636756964803, "Lymphocyte percentage increased": 12.375154195752822, "Lymphoedema": 8.078693398261807, "Macrocytosis": 7.539467870926835, "Madarosis": 12.716418761468312, "Malignant pleural effusion": 4.226371579235717, "Mastectomy": 11.271158667568884, "Mastitis": 4.794771848829444, "Mean cell haemoglobin increased": 15.136296549090344, "Mean cell volume increased": 19.303938368806342, "Memory impairment": 3.124506452542734, "Mental impairment": 2.191088853785059, "Metastases to bone": 3.5400524514929868, "Metastases to spine": 2.542620954370455, "Monocyte count decreased": 8.703226265953472, "Monocyte count increased": 2.8840458008700565, "Monocyte percentage increased": 6.399505226588549, "Mucosal inflammation": 3.053797236216902, "Musculoskeletal chest pain": 3.2017079246401745, "Nail discolouration": 3.3054509364241857, "Nail disorder": 8.246128167034152, "Nasal disorder": 2.09092391163993, "Nasal dryness": 2.674461582540237, "Nasopharyngitis": 2.2884028935643346, "Neoplasm progression": 68.2555624268292, "Neoplasm recurrence": 15.037202631584377, "Nerve injury": 2.6266081457591137, "Neuropathy peripheral": 3.808731998697672, "Neutropenia": 22.48738160592416, "Neutrophil count abnormal": 3.518087435560629, "Neutrophil count decreased": 16.266623718174003, "Oesophageal pain": 2.129525949807175, "Oesophageal stenosis": 2.423191209987982, "Oestrogen receptor assay positive": 13.603157350865322, 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error": 14.81427066978136, "Product dose omission issue": 4.559374596107146, "Product packaging difficult to open": 16.420189330666723, "Product prescribing error": 2.093324538622906, "Product prescribing issue": 2.313810353131592, "Product size issue": 3.366171400640936, "Product use complaint": 2.382343666943968, "Product use issue": 2.2082477185071743, "Pulmonary mass": 2.181105469812254, "Pulmonary oedema": 3.797774839825734, "Pulmonary thrombosis": 8.37846341871662, "Radiation injury": 19.61400538964656, "Red blood cell count abnormal": 14.155550118731448, "Red blood cell count decreased": 16.875308788060785, "Red cell distribution width increased": 7.305769321759988, "Scratch": 2.134012404711612, "Second primary malignancy": 30.31386584773108, "Sensitivity to weather change": 2.269953599690398, "Shoulder fracture": 2.3811836740252867, "Sinus disorder": 2.835330690625912, "Spinal disorder": 2.893871331538145, "Spinal fracture": 3.1020783815422317, "Spinal operation": 3.031787798664392, "Spinal pain": 2.137866065669257, "Stomatitis": 7.545353675502012, "Stress": 2.671282907922408, "Taste disorder": 2.473333381456002, "Terminal state": 2.163618043811311, "Thrombocytopenia": 2.60537054041191, "Thrombosis": 2.9159906254682384, "Tongue blistering": 2.3185653266195647, "Tongue disorder": 2.721550343365679, "Tooth abscess": 2.502978727528156, "Tooth disorder": 4.4198639745993145, "Tooth extraction": 6.648855815351578, "Tooth fracture": 2.051255639116788, "Tooth infection": 3.63872126070934, "Toothache": 2.162361963751906, "Trichorrhexis": 8.273808372941785, "Trigger finger": 2.8003998729384065, "Tumour haemorrhage": 2.2087708076208314, "Tumour marker abnormal": 30.668097765887072, "Tumour marker increased": 34.73127615964564, "Tumour pain": 9.45218343052788, "Upper limb fracture": 3.948078413036084, "Upper-airway cough syndrome": 3.0364516425144146, "Urinary tract infection": 3.3055363252894563, "Vein disorder": 2.638577001556369, "Vein rupture": 8.87763199863247, "Vitamin B12 decreased": 2.8125735884810448, "Vulvovaginal dryness": 2.7275776224284645, "Weight decreased": 2.150070288052819, "Weight fluctuation": 4.34702561632579, "White blood cell count abnormal": 14.032105495544236, "White blood cell count decreased": 20.233644487845453, "White blood cell disorder": 7.522830184668925, "Wound complication": 2.05245885469728, "Wound infection": 2.320097761082506}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/551.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/551.json
index 3102e93d167..138bb079d7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/551.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/551.json
@@ -1 +1 @@
-{"Alopecia ": 2.5560528388722874, "Arthritis ": 12.91222712264465, "Condition aggravated ": 3.106084975112421, "Crohn's disease ": 13.828168476310458, "Drug ineffective ": 5.131002570774772, "Injection site erythema ": 2.5795402305388357, "Injection site pain ": 7.634727393614623, "Injection site reaction ": 4.517619077376616, "Joint swelling ": 2.460918729537112, "Loss of therapeutic response ": 167.01291200352358, "Peripheral swelling ": 2.094863910594089, "Product substitution issue ": 11.137470791797783, "Psoriasis ": 25.684053552221773, "Skin exfoliation ": 11.894034104656086, "Skin reaction ": 13.726564452481314}
\ No newline at end of file
+{"Aspergillus infection": 55.08954281720174, "Atrial fibrillation": 10.007370602528798, "Blood lactate dehydrogenase increased": 11.660909976688318, "Bronchopulmonary aspergillosis": 20.694792117955508, "Cerebral aspergillosis": 287.7403297789392, "Chronic lymphocytic leukaemia": 316.3992028786959, "Chronic lymphocytic leukaemia recurrent": 753.4167143014894, "Cytopenia": 16.690475288569477, "Disease progression": 16.790761862684313, "Drug interaction": 3.371357128086994, "Drug resistance": 8.485543119963147, "Febrile neutropenia": 6.777115586950506, "Haemorrhage": 4.512287200584412, "Infection": 5.288100759325498, "Mantle cell lymphoma recurrent": 455.5528273194338, "Neutropenia": 6.133754055499338, "Neutrophil count decreased": 3.01895934381053, "Off label use": 3.158236447476081, "Pancytopenia": 3.5397316369364558, "Platelet count decreased": 3.817278220246769, "Progressive multifocal leukoencephalopathy": 38.77745130906629, "Rash maculo-papular": 3.65299281642972, "Splenomegaly": 14.468967682550687, "Therapeutic product effect incomplete": 5.515691145785869, "Therapy partial responder": 25.24757006552831, "Thrombocytopenia": 3.533494934157098, "Treatment failure": 2.6763459800547627, "Tumour lysis syndrome": 31.630603538295382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/552.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/552.json
index 071fd597482..44ad7ca8ab9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/552.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/552.json
@@ -1 +1 @@
-{"Disease progression ": 16.252868153578163}
\ No newline at end of file
+{"Abdominal tenderness": 3.410877309239667, "Accidental exposure to product by child": 2.037489263820788, "Accidental overdose": 3.6926340494637753, "Accidental poisoning": 14.743583935036874, "Acidosis": 7.246006245476541, "Acute generalised exanthematous pustulosis": 5.497423500303809, "Acute hepatic failure": 5.198536209734825, "Acute kidney injury": 4.391430470062005, "Acute respiratory distress syndrome": 2.382062540116234, "Agranulocytosis": 3.0137154871918246, "Akinesia": 3.960895766381687, "Alcohol poisoning": 3.729612664217967, "Allergy to animal": 9.175357807641348, "Anaphylactic reaction": 2.090677218960239, "Angioedema": 3.4970233298550104, "Angular cheilitis": 7.9874225207337854, "Anuria": 7.2769335264959665, "Apnoea": 3.631296901804918, "Apraxia": 5.172364318192487, "Areflexia": 3.50762368398444, "Aspiration": 4.54225494009999, "Atelectasis": 5.624286585018202, "Atrial septal defect": 3.859485214972025, "Bile acids increased": 61.41582330443742, "Blood bicarbonate decreased": 6.452367242388922, "Blood lactic acid increased": 2.1723422195706834, "Blood pH decreased": 8.454115236572726, "Blood pH increased": 53.51177802850528, "Blood urea increased": 3.1689928655357806, "Brain death": 5.066412453155303, "Brain injury": 3.330092388874432, "Brain oedema": 3.635715323157788, "Bronchial hyperreactivity": 5.398674588874039, "Bronchial wall thickening": 6.9248377859446, "Bronchitis chronic": 3.5857353558993936, "Cardiac arrest": 2.552187720480773, "Cardio-respiratory arrest": 6.738354162465168, "Cardiogenic shock": 2.041106759695461, "Cardiomegaly": 2.1579729183478453, "Central nervous system lesion": 2.3132078356378023, "Cleft lip": 10.109739423056384, "Cleft lip and palate": 10.489817364835014, "Cleft palate": 6.895170942029214, "Clonus": 8.130967822280532, "Clostridium difficile infection": 2.937779657568792, "Coagulopathy": 2.202746257509168, "Colitis ischaemic": 2.444441148385308, "Colitis microscopic": 2.4139553955588497, "Coma": 3.676952746331235, "Coma scale abnormal": 6.542061949641314, "Completed suicide": 17.919053205852165, "Congenital central nervous system anomaly": 10.467357041451663, "Congenital musculoskeletal disorder": 13.645697509034193, "Conjunctival hyperaemia": 2.098918728544862, "Cross sensitivity reaction": 12.514375501789168, "Depressed level of consciousness": 2.8995600580208354, "Dermatitis exfoliative": 3.088083754021449, "Dermatitis exfoliative generalised": 2.3934449847342383, "Device adhesion issue": 28.950730584148705, "Device dislocation": 14.110663322031057, "Device maintenance issue": 743.4573162383549, "Device malfunction": 2.5455265988379234, "Device power source issue": 62.711849612710495, "Diastolic dysfunction": 4.438616625349551, "Disease complication": 4.417866413052234, "Drug abuse": 3.3190646431895936, "Drug dose titration not performed": 12.809088712565975, "Drug eruption": 2.0056057109762158, "Drug hypersensitivity": 3.1942261297563386, "Drug interaction": 3.299103146964631, "Drug screen positive": 4.314457297995316, "Drug-induced liver injury": 2.536419936513905, "Duodenal ulcer": 3.2477249138437525, "Duodenal ulcer haemorrhage": 3.697066731239334, "Electrocardiogram QRS complex prolonged": 4.547230693119836, "Electrocardiogram QT prolonged": 2.023541868498093, "Electrocardiogram ST segment elevation": 6.101544281606271, "Electrocardiogram abnormal": 2.079868322699556, "Emergency care": 7.76404271422803, "Endometritis": 36.744256841442905, "Environmental exposure": 30.26608135453977, "Epidermal necrosis": 8.183632570142185, "Erection increased": 2.037564499430488, "Erythema multiforme": 2.542645888303666, "Escherichia infection": 4.67761650013148, "Eustachian tube dysfunction": 18.003712058957543, "Female sterilisation": 49.44178507727904, "Fine motor skill dysfunction": 13.427173322029796, "Fixed eruption": 3.0815867775439307, "Flushing": 2.109792529308372, "Gastric ulcer": 3.924211168396506, "Gastric ulcer haemorrhage": 3.72347004096194, "Gastritis erosive": 2.533927960427998, "Gastrointestinal erosion": 16.01021425643838, "Gastrointestinal haemorrhage": 2.494089515472328, "Gastrointestinal inflammation": 3.823729664809397, "Gastrointestinal sounds abnormal": 5.882996192688777, "Glomerulonephritis membranous": 7.434827410278267, "Grip strength decreased": 6.139970379343966, "Haematemesis": 3.154722094241915, "Haemodynamic instability": 10.204744273461664, "Heart disease congenital": 2.8984929862073123, "Heart valve incompetence": 7.822223871148866, "Hepatic failure": 2.5509820954148985, "Hepatic necrosis": 6.645869215485291, "Hepatic steatosis": 2.0216697672535373, "Hepatitis cholestatic": 2.32192566387324, "Hepatitis toxic": 2.314175832170516, "Hepatomegaly": 3.111446480438999, "Hepatosplenomegaly": 2.695171323125412, "Holoprosencephaly": 76.05493062621257, "Hyperkalaemia": 2.5297884008727545, "Hyperlactacidaemia": 24.455305479800668, "Hyperreflexia": 6.066033988604476, "Hypertonia": 3.195441236438478, "Hypoalbuminaemia": 3.1185802282696566, "Hypochromic anaemia": 7.818708061437475, "Hypopnoea": 3.6924967073905592, "Hypotension": 2.1556487399141235, "Ileal perforation": 16.40441571088534, "Inadequate analgesia": 5.982020252083279, "Incorrect drug administration rate": 18.85882844249825, "Incorrect product administration duration": 2.1952434858681915, "Infusion site discharge": 17.165168815656862, "Infusion site discomfort": 86.64669945403669, "Infusion site erythema": 11.321036271383736, "Infusion site induration": 68.27301634097113, "Infusion site irritation": 28.950730584148705, "Infusion site pain": 8.791612452961692, "Infusion site pruritus": 8.285468295992716, "Infusion site swelling": 15.67994701180688, "Intentional overdose": 15.42563573305376, "Intentional product misuse": 3.095496506239056, "Intervertebral disc disorder": 4.606975019570369, "Intervertebral disc protrusion": 2.263177869068653, "Ischaemia": 2.372733228347009, "Kidney malformation": 25.19540824670632, "Kounis syndrome": 11.838898999097168, "Lactic acidosis": 2.578609870747207, "Latent tuberculosis": 13.111466005016824, "Leukocytosis": 2.548119555363333, "Lip oedema": 3.4133699219745286, "Liver injury": 3.157679125370897, "Lower gastrointestinal haemorrhage": 2.552378735170446, "Lung infiltration": 2.0594952091627805, "Major depression": 2.246361793521384, "Maternal exposure timing unspecified": 3.561150708794245, "Mean cell haemoglobin concentration decreased": 10.539002001634856, "Medication error": 4.122416061940643, "Medication overuse headache": 38.600606785520434, "Mental status changes": 2.594181172410285, "Metabolic acidosis": 8.897707699755824, "Methaemoglobinaemia": 7.708713393385037, "Microcephaly": 10.278007081658211, "Micturition frequency decreased": 46.92675426571587, "Miosis": 2.6745878246892283, "Mitochondrial toxicity": 6.2847230363399085, "Mucosal disorder": 5.722286277135559, "Multiple organ dysfunction syndrome": 2.379473465686365, "Muscle spasticity": 3.649548247837165, "Mydriasis": 2.5652130632079517, "Nasal dryness": 5.938367951767789, "Nasal polyps": 3.6454367159063694, "Nerve compression": 7.566259766154312, "Nikolsky's sign": 7.631664031108398, "Normal newborn": 2.9850252416662397, "Nystagmus": 2.097273707735886, "Obstructive airways disorder": 2.246851247486843, "Oesophagitis": 2.7151886728225905, "Oligoarthritis": 45.2498501146721, "Oliguria": 3.410384022741265, "Oral mucosa erosion": 3.970336670804131, "Overdose": 6.127109600245635, "Patent ductus arteriosus": 7.528151899539772, "Peptic ulcer": 4.524677504824427, "Periorbital oedema": 3.1811899939487613, "Poisoning": 4.946990114197902, "Poisoning deliberate": 3.3126944559816027, "Polyarthritis": 2.2837519670866677, "Post-traumatic stress disorder": 2.6121524953192066, "Potentiating drug interaction": 2.097540495392128, "Product administration interrupted": 15.227805495879991, "Pseudomonal sepsis": 6.332117654840045, "Pseudomonas infection": 3.130919492115618, "Pulseless electrical activity": 5.761632120987281, "Purulent discharge": 10.317530946977111, "Renal tubular acidosis": 9.5684513474475, "Renal tubular necrosis": 4.582575040064681, "Respiratory acidosis": 4.929587209630282, "Respiratory arrest": 4.814101312041238, "Respiratory rate decreased": 3.916039449757093, "Respiratory symptom": 4.261932366142071, "Retching": 3.055541230683626, "Retinopathy": 2.3489330763816194, "Right atrial dilatation": 68.13190629996535, "Right ventricular dilatation": 33.74201514650552, "Right ventricular failure": 2.7268677848778764, "Sacral pain": 9.528411971130303, "Self-medication": 9.591364760801609, "Serotonin syndrome": 3.9816202556278215, "Shock": 4.611865754195066, "Shock haemorrhagic": 2.2647258410117925, "Sinus bradycardia": 2.42529241107542, "Sinus tachycardia": 2.7089106001893826, "Skin laceration": 4.153675847094446, "Skin swelling": 3.0046752110745136, "Slow response to stimuli": 3.294931053215848, "Somnolence": 2.51901274388108, "Sopor": 4.6657706130528735, "Spirometry abnormal": 20.954325284871675, "Staphylococcal sepsis": 2.547494862212154, "Stevens-Johnson syndrome": 7.218937774182322, "Stupor": 3.9890129483102506, "Substance abuse": 2.404189430538381, "Suicide attempt": 12.658943464403976, "Superinfection": 9.5817257377611, "Superior mesenteric artery syndrome": 72.34785944470897, "Suspected suicide": 46.90857714426173, "Synovial cyst": 5.268481860816761, "Systemic inflammatory response syndrome": 2.6127369136782645, "Systolic dysfunction": 31.049532992731024, "Therapeutic product effect increased": 4.964264467448023, "Throat tightness": 2.0557713115270677, "Tongue oedema": 2.665107685107109, "Toxic epidermal necrolysis": 8.512865051486944, "Toxicity to various agents": 12.239041255489708, "Tracheobronchitis": 25.90013908488394, "Transposition of the great vessels": 15.149587955244677, "Tricuspid valve incompetence": 3.979441477563959, "Tubulointerstitial nephritis": 4.036342410038358, "Type IV hypersensitivity reaction": 4.544151374555248, "Unresponsive to stimuli": 3.490164592379625, "Upper gastrointestinal haemorrhage": 4.464740182725083, "Upper respiratory tract infection": 2.2768713751579965, "Ventricular septal defect": 4.271314026917337, "Weight fluctuation": 3.526900854844486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/553.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/553.json
index fbcbe587913..5eb136f71b8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/553.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/553.json
@@ -1 +1 @@
-{"Chondrolysis ": 44027.57818524235, "Musculoskeletal pain ": 661.1240093632636}
\ No newline at end of file
+{"Blood glucose increased": 4.906519065630417, "Diarrhoea": 2.459774650754204, "Glycosylated haemoglobin increased": 35.549503557834065, "Pancreatitis acute": 23.105299434417457}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/554.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/554.json
index e784888ce40..d34f1e3cc08 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/554.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/554.json
@@ -1 +1 @@
-{"Condition aggravated ": 2.027760630417852, "Drug intolerance ": 3.585108058030616, "Dry eye ": 34.10584149134583, "Eye irritation ": 324.3741309271525, "Eye pain ": 72.48049292124732, "Eye pruritus ": 51.54901934553404, "Eye swelling ": 16.442496623357297, "Intentional product misuse ": 6.831764581064476, "Lacrimation increased ": 111.14353348151823, "Multiple use of single-use product ": 267.97990693400607, "Ocular discomfort ": 33.26831969137706, "Ocular hyperaemia ": 83.92988741684864, "Off label use ": 7.598423023086233, "Prescribed overdose ": 42.16403842664547, "Product availability issue ": 39.08392780175632, "Product use in unapproved indication ": 3.1376151924406703, "Recalled product administered ": 223.1545420209044, "Swelling of eyelid ": 40.99568776187496, "Therapy interrupted ": 52.68667732857445, "Vision blurred ": 6.614781387406226, "Visual impairment ": 5.959429557153886}
\ No newline at end of file
+{"Angioedema": 98.69102282093216, "Drug ineffective": 5.100589918539252, "Hereditary angioedema": 148.55685883911383, "Off label use": 6.079667940794496, "Therapy non-responder": 77.48586327448245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/555.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/555.json
index d72d9d741b5..291cb65cab1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/555.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/555.json
@@ -1 +1 @@
-{"Anxiety ": 4.527741045471823, "Arthritis ": 3.642187158944324, "Arthritis infective ": 363.0507514653518, "Blood pressure increased ": 3.490262830807408, "Blood pressure systolic increased ": 32.642047386628555, "Bone pain ": 5.148619987595221, "Cellulitis ": 29.26234992616037, "Device dislocation ": 365.3609996775903, "Fall ": 5.468389181090146, "Fluid retention ": 33.55202256210019, "Foot fracture ": 64.11176941463039, "Haemoglobin decreased ": 2.1114073126655204, "Hand fracture ": 147.86954815353883, "Heart rate decreased ": 41.69282799220811, "Hyperhidrosis ": 5.044083264446504, "Hypertension ": 4.2768633408657735, "Influenza ": 7.989167777702192, "Infusion related reaction ": 19.021352046489564, "Infusion site extravasation ": 144.8934447434867, "Injection site extravasation ": 166.32935373573164, "Insomnia ": 5.302679487247665, "Limb injury ": 20.03756307875125, "Localised infection ": 94.1912156113165, "Mobility decreased ": 18.187305108247585, "Neuralgia ": 26.18203562747009, "Pleural effusion ": 4.069871945152817, "Vein disorder ": 307.9689277842574, "Weight decreased ": 6.237837279806731, "Weight increased ": 7.849426230188255, "Wound ": 27.975798807876608, "Wound infection ": 220.4631259569844}
\ No newline at end of file
+{"Accelerated hypertension": 46.27348328858969, "Acute coronary syndrome": 7.110595663817508, "Acute lymphocytic leukaemia": 69.15736258283168, "Acute lymphocytic leukaemia recurrent": 126.7784429543712, "Acute myeloid leukaemia": 2.062949410630812, "Acute myocardial infarction": 7.349228006838453, "Allogenic stem cell transplantation": 129.94614167075676, "Amylase increased": 12.601941774524814, "Angina pectoris": 2.5644106512476155, "Angina unstable": 7.074902856258915, "Angiopathy": 9.050060055837887, "Arterial occlusive disease": 6.678339062934668, "Arteriosclerosis": 6.599810202144397, "Arteriosclerosis coronary artery": 4.056785561356703, "Atrial fibrillation": 5.980574816568642, "Benign prostatic hyperplasia": 4.691031022613292, "Blast cell crisis": 292.1844386071012, "Blast crisis in myelogenous leukaemia": 230.3105141951547, "Blindness unilateral": 5.637633234211379, "Bone marrow failure": 9.445390356738072, "Bone marrow transplant": 40.83326897485544, "Bone pain": 2.137808468907818, "Cardiac disorder": 2.729452683090871, "Cardiac failure": 5.098403386852058, "Cardiac failure acute": 5.71769684477199, "Cardiomyopathy": 3.5179272264288315, "Cardiotoxicity": 4.4571784064512965, "Cardiovascular disorder": 2.010681025695614, "Carotid arteriosclerosis": 47.80376620813438, "Carotid artery stenosis": 18.05575825649166, "Central nervous system leukaemia": 159.99395438148198, "Cerebral artery stenosis": 60.35980947481789, "Cerebral infarction": 10.697099509547677, "Cerebral ischaemia": 11.802743506450035, "Cerebrovascular accident": 3.1556094289511463, "Chemotherapy": 14.359773184809605, "Chronic myeloid leukaemia": 233.67049887803984, "Chronic myeloid leukaemia recurrent": 367.26038042018, "Chronic myeloid leukaemia transformation": 388.9019820992351, "Constipation": 2.2392532053641574, "Coronary artery disease": 6.018269049740005, "Coronary artery occlusion": 4.181051839897023, "Coronary artery stenosis": 28.538648969253117, "Cytogenetic analysis abnormal": 19.693262216928247, "Cytopenia": 21.95029798027997, "Death": 3.7045437915291592, "Dermatitis exfoliative": 16.309643829841363, "Disease complication": 52.22913201027892, "Disease progression": 3.887507361715729, "Drug resistance": 2.6884976361881665, "Dry eye": 3.6277618961705658, "Dry skin": 8.639024360005838, "Ejection fraction decreased": 4.9799410910838615, "Erectile dysfunction": 5.06324363834545, "Exfoliative rash": 8.586620657294072, "Febrile neutropenia": 2.08746355379326, "Full blood count abnormal": 2.176171772150969, "Full blood count decreased": 3.9702374987291673, "Graft versus host disease": 14.359605768883863, "Graft versus host disease in gastrointestinal tract": 12.296544679845432, "Graft versus host disease in skin": 27.43963679183444, "Haematocrit decreased": 2.0211491628069385, "Haematotoxicity": 12.952161655373692, "Hepatic failure": 2.4449472374071406, "Hepatomegaly": 2.1754795957608533, "Hepatotoxicity": 8.42043415909153, "Hyperlipidaemia": 2.1600304147834417, "Hypertension": 4.439291132210554, "Hypertensive crisis": 2.9854202902178293, "Hypertransaminasaemia": 2.419927285511357, "Hypertriglyceridaemia": 5.53918065904896, "Ichthyosis": 224.17622711282465, "Ichthyosis acquired": 216.95484361890703, "Infection": 2.499938531406007, "Intermittent claudication": 18.31691825185636, "Ischaemic stroke": 9.488444658453872, "Leukaemia recurrent": 31.68209624846668, "Leukocytosis": 5.77165108887904, "Lipase increased": 22.64525056272141, "Liver disorder": 2.3031826408148737, "Liver function test increased": 2.1667793031086, "Lymphocyte count decreased": 2.385453769951053, "Mitral valve incompetence": 4.1329524260223565, "Moyamoya disease": 138.05836805067898, "Multiple organ dysfunction syndrome": 2.38448957811382, "Myocardial infarction": 3.066776604543855, "Myocardial ischaemia": 6.990298694124772, "Neoplasm progression": 20.95868142075205, "Neutropenia": 2.287120264787835, "No adverse event": 2.43393812076235, "Off label use": 3.880806476298702, "Pancreatic enzymes increased": 13.177115422234298, "Pancreatitis": 11.03762090090398, "Pancreatitis acute": 5.193429312729352, "Pancytopenia": 5.2916260186285, "Pericardial effusion": 7.548719133276303, "Peripheral arterial occlusive disease": 69.0623561839334, "Peripheral artery occlusion": 12.879366070197138, "Peripheral artery stenosis": 62.84336830361444, "Peripheral artery thrombosis": 11.320424895315822, "Peripheral ischaemia": 6.444370132216057, "Peripheral vascular disorder": 4.207833105397713, "Philadelphia chromosome positive": 93.7088246239684, "Philadelphia positive acute lymphocytic leukaemia": 2288.780376911525, "Pityriasis rubra pilaris": 53.93698520196627, "Platelet count abnormal": 9.54351824708954, "Platelet count decreased": 3.3027509225960663, "Pleural effusion": 5.5215259049540215, "Pneumonia": 2.5469017214902885, "Pneumonia fungal": 11.280808610512429, "Posterior reversible encephalopathy syndrome": 5.8027476188123925, "Prinzmetal angina": 34.87955655555459, "Product administered to patient of inappropriate age": 15.700536603397218, "Pulmonary arterial hypertension": 2.6699524652904234, "Pulmonary hypertension": 4.181125461880895, "Red blood cell count decreased": 2.3439505318834817, "Renal artery stenosis": 64.84892343925344, "Retinal artery occlusion": 7.683465024856064, "SARS-CoV-2 test positive": 2.3584602267752177, "Scleroderma": 9.602887915914474, "Sepsis": 3.915848959366692, "Septic shock": 6.230567785036587, "Skin exfoliation": 6.776978661121519, "Skin lesion": 2.024141604145083, "Skin toxicity": 5.523239062534077, "Splenomegaly": 2.951571122237291, "Stem cell transplant": 80.01820927072826, "Sudden death": 3.120851558584854, "Supraventricular tachycardia": 2.224836690995568, "Therapeutic response decreased": 2.0393038060943285, "Therapy non-responder": 6.666730911417527, "Therapy partial responder": 5.7934551053142505, "Thrombocytopenia": 5.372986390692784, "Thrombotic microangiopathy": 2.9541735766336026, "Transaminases increased": 3.2278478721246118, "Transient ischaemic attack": 3.4443135580174005, "Transplant": 65.54273089259819, "Treatment noncompliance": 4.464177811067646, "Tumour marker increased": 6.6734482241142175, "Unevaluable event": 3.4328042221818205, "Vascular occlusion": 12.789059565982903, "Venoocclusive liver disease": 6.92449043178623, "Ventricular hypokinesia": 6.815515388489292, "White blood cell count increased": 2.877212941188598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/556.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/556.json
index 99267426e1c..5e25c0fda47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/556.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/556.json
@@ -1 +1 @@
-{"Toxicity to various agents ": 119.73032131122972}
\ No newline at end of file
+{"Hyperglycaemic hyperosmolar nonketotic syndrome": 2439.3512547825017}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/557.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/557.json
index b586aa2be8b..475e05d99bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/557.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/557.json
@@ -1 +1 @@
-{"Condition aggravated ": 5.788753732604919, "Death ": 2.082546645846126, "Dyspnoea ": 2.672147067415031, "Foetal exposure during pregnancy ": 16.425739907769593, "Low birth weight baby ": 135.5415074795063, "Maternal exposure during pregnancy ": 17.1657129290093, "Premature baby ": 67.05813794476613, "Premature delivery ": 100.909144764413, "Product use in unapproved indication ": 4.2361299705820095, "Pulmonary arterial hypertension ": 133.50185266869389}
\ No newline at end of file
+{"Alopecia": 2.5560528388722874, "Arthritis": 12.91222712264465, "Condition aggravated": 3.106084975112421, "Crohn's disease": 13.828168476310458, "Drug ineffective": 5.130964630364529, "Injection site erythema": 2.5795402305388357, "Injection site pain": 7.63463169650159, "Injection site reaction": 4.517619077376616, "Joint swelling": 2.460918729537112, "Loss of therapeutic response": 167.01291200352358, "Peripheral swelling": 2.094863910594089, "Product substitution issue": 11.137470791797783, "Psoriasis": 25.684053552221773, "Skin exfoliation": 11.894034104656086, "Skin reaction": 13.726564452481314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/558.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/558.json
index dd65c3e4c15..bdb592874f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/558.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/558.json
@@ -1 +1 @@
-{"Blast crisis in myelogenous leukaemia ": 141.51094928623797, "Blood pressure fluctuation ": 4.052033348550526, "Blood test abnormal ": 7.181520238101033, "Chronic graft versus host disease ": 56.18357150192813, "Chronic myeloid leukaemia ": 96.9391996516454, "Chronic myeloid leukaemia recurrent ": 141.45313302170487, "Complex regional pain syndrome ": 37.07209115343562, "Cytogenetic analysis abnormal ": 551.4544893422169, "Cytopenia ": 26.45298438250614, "Disease progression ": 5.030803122872174, "Disease recurrence ": 4.067362611445565, "Drug ineffective ": 2.145950680162116, "Drug ineffective for unapproved indication ": 2.945392797713113, "Drug interaction ": 2.1768250265932623, "Drug intolerance ": 10.132902389397584, "Drug resistance ": 45.99026976991454, "Dry skin ": 2.7122510713922305, "Febrile neutropenia ": 3.0719832743901807, "Fluid retention ": 4.42129688860326, "Gastrointestinal stromal tumour ": 255.4870030956045, "Gastrooesophageal reflux disease ": 2.3583125643022504, "Gene mutation ": 62.62944124860421, "Generalised oedema ": 11.580828066156808, "Haematotoxicity ": 20.50221729377359, "Hepatotoxicity ": 5.330414666910616, "Hunger ": 11.328279483676983, "Hyperkeratosis ": 16.53611659902419, "Lactose intolerance ": 37.813715070727866, "Lung disorder ": 3.404027941339955, "Malignant neoplasm progression ": 16.41465427309384, "Metastases to liver ": 27.180022868590324, "Metastases to peritoneum ": 48.13174253446147, "Mouth swelling ": 7.228522037921586, "Mouth ulceration ": 2.986113713927086, "Movement disorder ": 2.7920799647795715, "Mucosal inflammation ": 2.3608688022802897, "Myelosuppression ": 2.4957919360987244, "Neoplasm progression ": 4.908439294023079, "Neoplasm recurrence ": 30.84256562737216, "Neuropathy peripheral ": 2.0313274762088147, "Neurotoxicity ": 4.388141512395203, "Neutropenia ": 2.325218513097499, "Odynophagia ": 9.137249758967762, "Oedema ": 3.0447025153450173, "Oral mucosal blistering ": 8.304051904634319, "Palmar-plantar erythrodysaesthesia syndrome ": 2.707908004736528, "Pancytopenia ": 4.118235984590463, "Pericardial effusion ": 3.617691784872147, "Periorbital oedema ": 9.42145148794145, "Peripheral arterial occlusive disease ": 15.406600670784329, "Philadelphia chromosome positive ": 162.23793971528576, "Pleural effusion ": 3.405736471819357, "Recurrent cancer ": 26.689566410059797, "Scleroderma ": 21.877934745389677, "Second primary malignancy ": 30.34395867149284, "Skin exfoliation ": 2.045808915975054, "Skin toxicity ": 14.279151036202869, "Splenomegaly ": 6.260347917411717, "Stomatitis ": 2.403518240615583, "Therapeutic response decreased ": 7.140173436846499, "Therapy non-responder ": 9.308598914826076, "Thrombocytopenia ": 2.58870878004068, "Treatment failure ": 8.046699336737802, "Type 2 diabetes mellitus ": 3.774559951740285, "White blood cell count increased ": 5.744098437062779}
\ No newline at end of file
+{"Disease progression": 16.252868153578163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/559.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/559.json
index cb134be036a..f949a05adca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/559.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/559.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 5.146235502511118, "Atrial fibrillation ": 10.47502890723756, "Basal cell carcinoma ": 11.642699131359116, "Bone pain ": 2.08765931535678, "Cellulitis ": 3.318917583278252, "Cholestasis ": 4.466737592476926, "Chronic lymphocytic leukaemia ": 135.1061443231389, "Chronic lymphocytic leukaemia recurrent ": 199.70422061659372, "Contusion ": 4.028294973911446, "Disease progression ": 3.7532321926420704, "Drug interaction ": 2.075609957319448, "Dry eye ": 3.828423252415073, "Dyspepsia ": 2.057980807407374, "Haematoma ": 2.689876820169475, "Haemorrhage ": 3.362983453119168, "Immunodeficiency ": 11.252779624983162, "Incorrect dose administered ": 3.8633513052893433, "Lymphoedema ": 10.47366588239726, "Muscle spasms ": 2.054079344308416, "Neuropathy peripheral ": 2.6179007956053253, "Neutropenia ": 2.1251876958864395, "Neutrophil count decreased ": 3.2400650963423643, "Night sweats ": 3.34319206782186, "Oedema peripheral ": 2.888846967565688, "Off label use ": 2.646450103726988, "Onychoclasis ": 46.11474460969721, "Pancytopenia ": 2.351885161005599, "Platelet count decreased ": 3.255598384060771, "Pleural effusion ": 4.370311145612399, "Richter's syndrome ": 176.97983750317442, "Tumour lysis syndrome ": 22.484426672495147, "Urinary tract infection ": 3.0431267281356065, "White blood cell count increased ": 4.255781463990515}
\ No newline at end of file
+{"Chondrolysis": 44027.57818524235, "Musculoskeletal pain": 661.1240093632636}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/56.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/56.json
index 15b9cd9e9ba..3e3589f3d6c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/56.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/56.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 85.13577901866176, "Cephalhaematoma ": 4682.721906056164, "Crying ": 15.518658075751198, "Depression ": 3.773920480370724, "Drug abuse ": 11.680945098091678, "Drug interaction ": 4.003843311249107, "Encephalopathy ": 35.93279451767134, "Menopausal symptoms ": 173.7794336599358, "Metal poisoning ": 1080.051204159216, "Product use in unapproved indication ": 6.209801356723792, "Rhabdomyolysis ": 17.955012444715173, "Self-injurious ideation ": 198.9899244718566, "Weight increased ": 4.076698886255223}
\ No newline at end of file
+{"Hypersensitivity": 11.663667858783253, "Limb injury": 154.76060111989247, "Throat irritation": 69.15917243321545}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/560.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/560.json
index 9a0ffd59267..bd6bd2f935d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/560.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/560.json
@@ -1 +1 @@
-{"Febrile neutropenia ": 10.661499865196593, "Interstitial lung disease ": 28.94273436018254, "Liver disorder ": 10.704866227543205, "Malignant neoplasm progression ": 5.664032268194773, "Platelet count decreased ": 5.173110659946177, "Pneumonitis ": 20.84180021060519, "Radiation pneumonitis ": 1927.4831366743665}
\ No newline at end of file
+{"Condition aggravated": 2.027760630417852, "Drug intolerance": 3.585108058030616, "Dry eye": 34.10584149134583, "Eye irritation": 324.3741309271525, "Eye pain": 72.48049292124732, "Eye pruritus": 51.54901934553404, "Eye swelling": 16.442496623357297, "Intentional product misuse": 6.831764581064476, "Lacrimation increased": 111.14353348151823, "Multiple use of single-use product": 267.97990693400607, "Ocular discomfort": 33.26831969137706, "Ocular hyperaemia": 83.92988741684864, "Off label use": 7.598123681463827, "Prescribed overdose": 42.16403842664547, "Product availability issue": 39.08392780175632, "Product use in unapproved indication": 3.13751735246158, "Recalled product administered": 223.1545420209044, "Swelling of eyelid": 40.99568776187496, "Therapy interrupted": 52.68667732857445, "Vision blurred": 6.614781387406226, "Visual impairment": 5.959429557153886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/561.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/561.json
index 403a495d09a..1e1fa63a762 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/561.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/561.json
@@ -1 +1 @@
-{"Application site erythema ": 46.70213617853167, "Application site scab ": 497.746941445022, "Blister ": 5.029351794573634, "Burning sensation ": 4.472287690951847, "Erythema ": 6.580728444169679, "Erythema multiforme ": 25.1010419806324, "Haemorrhage ": 2.700703525230742, "Inflammation ": 13.30360113259045, "Influenza like illness ": 2.977177588933304, "Oedema ": 8.075763175232542, "Off label use ": 4.94419887528734, "Scab ": 109.0103218570603, "Skin abrasion ": 54.20172693234086, "Skin erosion ": 174.81077875704233, "Skin exfoliation ": 9.383746553014925, "Skin lesion ": 11.612426866497596, "Skin reaction ": 15.8383975256756, "Skin ulcer ": 13.926701525783388, "Skin weeping ": 219.5377969668076, "Ulcer ": 44.77487349557784}
\ No newline at end of file
+{"Anxiety": 4.527741045471823, "Arthritis": 3.642187158944324, "Arthritis infective": 363.0507514653518, "Blood pressure increased": 3.490201569664092, "Blood pressure systolic increased": 32.642047386628555, "Bone pain": 5.148619987595221, "Cellulitis": 29.26234992616037, "Device dislocation": 365.3609996775903, "Fall": 5.468248970061794, "Fluid retention": 33.55202256210019, "Foot fracture": 64.11176941463039, "Haemoglobin decreased": 2.1114073126655204, "Hand fracture": 147.7608236708438, "Heart rate decreased": 41.69282799220811, "Hyperhidrosis": 5.044083264446504, "Hypertension": 4.276819181744962, "Influenza": 7.989167777702192, "Infusion related reaction": 19.021352046489564, "Infusion site extravasation": 144.8934447434867, "Injection site extravasation": 166.32935373573164, "Insomnia": 5.302679487247665, "Limb injury": 20.03756307875125, "Localised infection": 94.1912156113165, "Mobility decreased": 18.187305108247585, "Neuralgia": 26.18203562747009, "Pleural effusion": 4.069497260638584, "Vein disorder": 307.9689277842574, "Weight decreased": 6.237837279806731, "Weight increased": 7.849426230188255, "Wound": 27.97323113945542, "Wound infection": 220.4631259569844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/562.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/562.json
index 7a284276502..8f73fbf5110 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/562.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/562.json
@@ -1 +1 @@
-{"Anaemia ": 2.505392995944377, "Cardiac failure ": 4.583356843038923, "Disease progression ": 5.613114123184182, "Febrile neutropenia ": 5.969290767559164, "General physical health deterioration ": 2.60347905363697, "Infection ": 3.7309862787241928, "Interstitial lung disease ": 4.273957163611622, "Neutropenia ": 14.763061175402052, "Pancytopenia ": 10.900286304644728, "Plasma cell myeloma ": 88.85475027703849, "Pneumonia ": 3.680344077622951, "Rash maculo-papular ": 4.417619662793072, "Sepsis ": 4.741339880811824, "Thrombocytopenia ": 10.067001500856446}
\ No newline at end of file
+{"Toxicity to various agents": 119.73032131122972}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/563.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/563.json
index d5f7f8e0f41..f133faaa86d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/563.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/563.json
@@ -1 +1 @@
-{"Cough ": 9.19720917889573, "Death ": 2.4906504656237733, "Device issue ": 63.90759022640978, "Dyskinesia ": 22.129918832832896}
\ No newline at end of file
+{"Condition aggravated": 5.788753732604919, "Death": 2.082546645846126, "Dyspnoea": 2.672107369765862, "Foetal exposure during pregnancy": 16.425739907769593, "Low birth weight baby": 135.5415074795063, "Maternal exposure during pregnancy": 17.1657129290093, "Premature baby": 67.05813794476613, "Premature delivery": 100.909144764413, "Product use in unapproved indication": 4.235997881048182, "Pulmonary arterial hypertension": 133.50185266869389}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/564.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/564.json
index 85c1e39b79f..9fe75c199a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/564.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/564.json
@@ -1 +1 @@
-{"Abscess ": 2.1076322238246754, "Acute generalised exanthematous pustulosis ": 2.700346096947215, "Acute respiratory distress syndrome ": 2.0402518939352268, "Anaemia ": 32.273498398476804, "Anal abscess ": 11.879287286122594, "Anal fissure ": 11.846661823899442, "Anal haemorrhage ": 13.15985497548179, "Anal pruritus ": 156.10212426211726, "Anorectal discomfort ": 47.329415359232186, "Anorectal disorder ": 69.15428657856077, "Aphthous ulcer ": 3.3777359831663016, "Aplastic anaemia ": 4.699734438463656, "Ascites ": 6.281502988457305, "Asthenia ": 2.513329247470314, "Bacteraemia ": 2.582092121152389, "Blood bilirubin increased ": 2.1171747402475107, "Blood creatinine abnormal ": 5.753007920460614, "Blood creatinine increased ": 3.3260236428981806, "Blood thyroid stimulating hormone increased ": 5.017106699976378, "Blood uric acid increased ": 10.641717064275609, "Bone marrow failure ": 6.5768804494509565, "Cholecystitis acute ": 6.322766785277191, "Cutaneous vasculitis ": 2.1099434692166, "Decreased appetite ": 2.799763450089041, "Depression ": 3.332999509911333, "Dermatitis ": 4.769012724621072, "Dermatitis bullous ": 3.1527492325868445, "Dermatitis exfoliative generalised ": 5.134749339016444, "Drug eruption ": 3.0433723786696665, "Drug reaction with eosinophilia and systemic symptoms ": 13.482435657217954, "Dry skin ": 4.504093809964141, "Eczema ": 3.3150302754689247, "Emotional disorder ": 2.001472889594369, "Encephalopathy ": 4.113972515939547, "Eosinophilia ": 4.810070668988482, "Erysipelas ": 3.220784653708336, "Erythema multiforme ": 3.1874541747312883, "Escherichia bacteraemia ": 22.441856504678576, "Face oedema ": 4.428952767510319, "Food aversion ": 9.583655957208135, "Furuncle ": 5.748901220733634, "Gastroenteritis ": 3.7179323155082935, "Gastrointestinal necrosis ": 11.24826156720184, "General physical health deterioration ": 2.3380470882666584, "Gingival bleeding ": 2.909971761452355, "Gingivitis ": 3.012246640751563, "Haematocrit decreased ": 2.9023747322074533, "Haemoglobin decreased ": 11.314917350879831, "Haemolytic anaemia ": 2.962167094576873, "Haemorrhoidal haemorrhage ": 17.434684076443634, "Haemorrhoids ": 20.332976185088366, "Hepatic cirrhosis ": 8.140975922628007, "Hepatic encephalopathy ": 3.016371032849432, "Hepatic failure ": 3.059422955011196, "Hepatitis C ": 2.138588627408528, "Hepatocellular carcinoma ": 2.581830366445286, "Hyperbilirubinaemia ": 2.2880024339723497, "Hyperthermia ": 3.2305144162995467, "Hypertriglyceridaemia ": 3.9926395481990777, "Hyperuricaemia ": 14.17020391769327, "Leukopenia ": 6.723911925873681, "Liver transplant ": 19.206452201029723, "Lymphadenopathy mediastinal ": 14.850550416853643, "Lymphopenia ": 2.871220037072409, "Mental disorder ": 2.429141203861877, "Mood swings ": 3.250206722718535, "Multiple organ dysfunction syndrome ": 3.2953642402732037, "Neutropenia ": 4.546049100833519, "Oedema ": 2.2834940836454782, "Oedema peripheral ": 2.2919966713737905, "Oral candidiasis ": 3.4666639284750143, "Oral disorder ": 2.899656222909162, "Oral pain ": 2.1455777641952323, "Otitis media ": 4.32768758828345, "Pancreatitis acute ": 3.8287733213352526, "Pancytopenia ": 7.725414422896303, "Panniculitis ": 4.639197831916441, "Platelet count decreased ": 3.2438189480513557, "Portal vein thrombosis ": 3.664772253673176, "Proctalgia ": 58.57944069348382, "Proctitis ": 3.2245793420937776, "Pruritus ": 4.195318174229154, "Pustule ": 3.872909193914136, "Rash ": 7.534301950423666, "Rash erythematous ": 2.3890673200387718, "Rash maculo-papular ": 5.180607521132699, "Rectal haemorrhage ": 4.506706422843994, "Rectal tenesmus ": 33.8738037951446, "Respiratory tract infection ": 2.2636438948909268, "Sarcoidosis ": 4.3545107438653625, "Sepsis ": 3.3123445004683165, "Septic shock ": 4.183588544990558, "Skin lesion ": 3.320614504559782, "Skin reaction ": 7.345750598595121, "Spontaneous bacterial peritonitis ": 42.50509988842207, "Staphylococcal sepsis ": 15.72155269759164, "Thrombocytopenia ": 7.665730324851553, "Toxic skin eruption ": 13.5481835008529, "Transfusion ": 3.2554820930583794, "Treatment noncompliance ": 2.0318202868733697, "Urinary tract infection ": 2.421747718299109, "Urosepsis ": 5.3671494703549625, "Varices oesophageal ": 7.966398189541869, "Viral load increased ": 13.896632287420111, "Virologic failure ": 5.280518751635785, "Weight decreased ": 2.4820348469567324}
\ No newline at end of file
+{"Blast crisis in myelogenous leukaemia": 141.07187486164864, "Blood pressure fluctuation": 4.039463015024875, "Blood test abnormal": 7.159241529212811, "Chronic graft versus host disease": 56.00922460109511, "Chronic myeloid leukaemia": 96.63830014303232, "Chronic myeloid leukaemia recurrent": 141.01430962269995, "Complex regional pain syndrome": 36.95708549824349, "Cytogenetic analysis abnormal": 549.742567501261, "Cytopenia": 26.3497850447522, "Disease progression": 5.015185588122059, "Disease recurrence": 4.054744130744094, "Drug ineffective": 2.139267357075999, "Drug ineffective for unapproved indication": 2.9362559811529905, "Drug interaction": 2.1700677979581444, "Drug intolerance": 10.10143224235637, "Drug resistance": 45.847391323599005, "Dry skin": 2.703836652337521, "Febrile neutropenia": 3.062450639921827, "Fluid retention": 4.40757893888186, "Gastrointestinal stromal tumour": 254.6933176216501, "Gastrooesophageal reflux disease": 2.350995430253873, "Gene mutation": 62.43513421369017, "Generalised oedema": 11.544894269482665, "Haematotoxicity": 20.43860401847871, "Hepatotoxicity": 5.313876001116438, "Hunger": 11.293136601738532, "Hyperkeratosis": 16.484816635549095, "Lactose intolerance": 37.69640595005169, "Lung disorder": 3.393466268690392, "Malignant neoplasm progression": 16.363631843459284, "Metastases to liver": 27.095642301184416, "Metastases to peritoneum": 47.98240804771447, "Mouth swelling": 7.206097518885825, "Mouth ulceration": 2.9768505782505854, "Movement disorder": 2.7834182933234723, "Mucosal inflammation": 2.353545219966935, "Myelosuppression": 2.48804653982757, "Neoplasm progression": 4.893207978952876, "Neoplasm recurrence": 30.74688762020015, "Neuropathy peripheral": 2.024962921710712, "Neurotoxicity": 4.374529189614153, "Neutropenia": 2.31790110443291, "Odynophagia": 9.10890464533019, "Oedema": 3.0352545354356035, "Oral mucosal blistering": 8.27829216455867, "Palmar-plantar erythrodysaesthesia syndrome": 2.6995066922161324, "Pancytopenia": 4.10545514944025, "Pericardial effusion": 3.606468609102656, "Periorbital oedema": 9.392224739045629, "Peripheral arterial occlusive disease": 15.358808374368612, "Philadelphia chromosome positive": 161.73462635180908, "Pleural effusion": 3.394855602726898, "Recurrent cancer": 26.60677371133636, "Scleroderma": 21.810067991283336, "Second primary malignancy": 30.249790175017008, "Skin exfoliation": 2.0394623476556317, "Skin toxicity": 14.214434715056305, "Splenomegaly": 6.240926892437125, "Stomatitis": 2.3960608470048106, "Therapeutic response decreased": 7.118015100878171, "Therapy non-responder": 9.27889777408124, "Thrombocytopenia": 2.580429559702687, "Treatment failure": 8.021719892622633, "Type 2 diabetes mellitus": 3.762850403724652, "White blood cell count increased": 5.725177995073194}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/565.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/565.json
index 614746a334d..ffbd1df6123 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/565.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/565.json
@@ -1 +1 @@
-{"Adverse drug reaction ": 3.8641377412606337, "Aphonia ": 4.973774797886219, "Asthma ": 7.076449886107372, "Atrial fibrillation ": 2.9188989170534034, "Bronchitis ": 11.783268542761968, "Cardiac disorder ": 2.263635782204124, "Cardiac operation ": 7.908916315228619, "Cataract ": 3.797578380517582, "Cataract operation ": 22.82100302744276, "Chest discomfort ": 2.095267461819474, "Choking ": 16.182369495033704, "Chronic obstructive pulmonary disease ": 44.25154855779144, "Colon cancer ": 3.6854887227287287, "Colonoscopy ": 68.13562467156547, "Condition aggravated ": 2.3389170161476804, "Cough ": 5.096581450569663, "Dementia ": 2.224813248590635, "Device use error ": 32.54899279044496, "Diabetes mellitus ": 2.021314823318044, "Dry mouth ": 2.0966926661652887, "Dry throat ": 5.337692142926777, "Dysphonia ": 5.983139677246797, "Dyspnoea ": 5.131361025473262, "Dyspnoea exertional ": 2.135537577371595, "Dysuria ": 3.537017732191505, "Emphysema ": 6.027904355666179, "Eye pain ": 2.534808443364394, "Fall ": 2.709913364685192, "Full blood count abnormal ": 7.719024628920669, "Glaucoma ": 10.181196200405982, "Hospitalisation ": 9.29241578335014, "Ill-defined disorder ": 5.66829416162152, "Illness ": 3.4209387777808127, "Increased bronchial secretion ": 31.689351932243348, "Influenza ": 2.1885825963465426, "Intentional underdose ": 10.543246415066337, "Intercepted medication error ": 73.12638411309189, "Intestinal obstruction ": 2.5006485524496425, "Labelled drug-drug interaction medication error ": 12.478805454018644, "Loss of personal independence in daily activities ": 6.226696659294275, "Lung disorder ": 5.439000893572809, "Lung neoplasm malignant ": 13.09634456805191, "Macular degeneration ": 4.22004828739168, "Micturition disorder ": 12.138668609296312, "Multiple allergies ": 15.7555353573988, "Nasopharyngitis ": 2.213317363099767, "Neoplasm malignant ": 3.883804197451501, "Obstructive airways disorder ": 4.522496775053304, "Oral candidiasis ": 4.793885048519384, "Oxygen saturation decreased ": 3.496080049811848, "Oxygen therapy ": 63.59037986865131, "Pneumonia ": 7.466126234833232, "Pneumothorax ": 10.127286651124235, "Pollakiuria ": 2.688744731727493, "Prescribed underdose ": 4.582914788213763, "Product complaint ": 12.419809605101712, "Product dispensing error ": 5.543423532013192, "Product dose omission issue ": 7.16727555236977, "Product use in unapproved indication ": 4.194030525106931, "Productive cough ": 8.02698776465279, "Pulmonary congestion ": 10.464569005109356, "Rehabilitation therapy ": 48.49524189841461, "Respiratory tract congestion ": 12.982931428156302, "Respiratory tract infection ": 9.707100258518134, "Rhinorrhoea ": 2.681956772739372, "Rib fracture ": 6.063877870495214, "Secretion discharge ": 5.714809058740615, "Sleep apnoea syndrome ": 4.356379543840764, "Sleep disorder due to a general medical condition ": 18.40221145482263, "Spinal fracture ": 3.305484729785217, "Sputum discoloured ": 13.311410504466622, "Sputum increased ": 18.44765925060612, "Staphylococcal infection ": 2.921068007709645, "Stent placement ": 6.058443078894984, "Surgery ": 4.124536575893146, "Therapeutic product effect incomplete ": 6.216511012375739, "Throat irritation ": 4.328323319820536, "Underdose ": 9.472191046330677, "Urinary retention ": 8.69593521411426, "Viral infection ": 3.357708832804083, "Vision blurred ": 2.329794543574881, "Wheezing ": 10.93278925054894, "Wrong technique in device usage process ": 24.373815622404315}
\ No newline at end of file
+{"Acute myeloid leukaemia": 5.135367043699268, "Atrial fibrillation": 10.452591822005957, "Basal cell carcinoma": 11.618107700287352, "Bone pain": 2.083249806061348, "Cellulitis": 3.311907246670537, "Cholestasis": 4.457303047739548, "Chronic lymphocytic leukaemia": 134.70491792913182, "Chronic lymphocytic leukaemia recurrent": 199.282431268059, "Contusion": 4.019782498584644, "Disease progression": 3.745300834516621, "Drug interaction": 2.0712234680230277, "Dry eye": 3.820337911851313, "Dyspepsia": 2.053633532293186, "Haematoma": 2.6841948705323198, "Haemorrhage": 3.355877402791156, "Immunodeficiency": 11.229011124183092, "Incorrect dose administered": 3.855189611130309, "Lymphoedema": 10.451546308310611, "Muscle spasms": 2.049739279131224, "Neuropathy peripheral": 2.6122906656224485, "Neutropenia": 2.120605440374224, "Neutrophil count decreased": 3.2332200024501176, "Night sweats": 3.336130457799656, "Oedema peripheral": 2.99232698550086, "Off label use": 2.6407485759833667, "Onychoclasis": 46.01733734972725, "Pancytopenia": 2.346917043031392, "Platelet count decreased": 3.2487183956214603, "Pleural effusion": 4.360675927876917, "Richter's syndrome": 176.60604268410717, "Tumour lysis syndrome": 22.43692958919648, "Urinary tract infection": 3.0366970307247416, "White blood cell count increased": 4.245978986419565}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/566.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/566.json
index 46945d16022..2b4f107885c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/566.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/566.json
@@ -1 +1 @@
-{"Alopecia ": 2.045855905600176, "Anaemia ": 2.7213039670509187, "General physical health deterioration ": 2.6485928680290987, "Hepatic function abnormal ": 5.055162197363615, "Hyperbilirubinaemia ": 15.098558188528974, "Hyperlipidaemia ": 33.96573037562357, "Hypertriglyceridaemia ": 28.139140514324016, "Immune reconstitution inflammatory syndrome ": 37.928620840209845, "Lactic acidosis ": 10.615151331617422, "Lipoatrophy ": 131.48348004087248, "Lipodystrophy acquired ": 138.6639156308147, "Nephrolithiasis ": 6.733526716356552, "Osteonecrosis ": 2.0354347674550377, "Pancreatitis ": 3.195000741685373, "Progressive multifocal leukoencephalopathy ": 79.22306257314399, "Urinary tract infection ": 2.3910834119170024}
\ No newline at end of file
+{"Febrile neutropenia": 10.661499865196593, "Interstitial lung disease": 28.94273436018254, "Liver disorder": 10.704866227543205, "Malignant neoplasm progression": 5.664032268194773, "Platelet count decreased": 5.173110659946177, "Pneumonitis": 20.84180021060519, "Radiation pneumonitis": 1927.4831366743665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/567.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/567.json
index 609f3d47b16..2f6e63d6f5a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/567.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/567.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 2.6070964307545883, "Abnormal faeces ": 4.7365412803820215, "Allergy to metals ": 68.33082693779392, "Apathy ": 6.97649788629731, "Apnoea ": 42.26384642761485, "Attention deficit hyperactivity disorder ": 11.203989528457498, "Autism spectrum disorder ": 28.138576039174293, "Bradycardia ": 2.021709735785601, "Bronchiolitis ": 14.631801249887712, "Bronchitis ": 4.793074176553232, "Conjunctivitis ": 6.216057018745153, "Crying ": 39.158839085292406, "Cyanosis ": 11.905728526931576, "Dermatitis atopic ": 28.100623535048165, "Developmental delay ": 31.43178285960059, "Dyskinesia ": 3.4374250120919583, "Ear infection ": 4.699601217103091, "Eczema ": 2.3981527868361106, "Encephalopathy ": 2.25666709519876, "Epilepsy ": 3.900284836279887, "Eye movement disorder ": 17.36099878463675, "Febrile convulsion ": 81.01039778465645, "Flatulence ": 2.260057314961529, "Food allergy ": 6.37120734022315, "Gastroenteritis ": 11.904862449586364, "Gaze palsy ": 16.670475127604053, "Generalised tonic-clonic seizure ": 3.984424650539563, "Haematochezia ": 6.56523801738394, "High-pitched crying ": 392.15024004063065, "Hyperpyrexia ": 76.74711253996689, "Hypertonia ": 11.751743295801267, "Hyporesponsive to stimuli ": 28.803101408203595, "Hypotonia ": 29.24185632867904, "Hypotonic-hyporesponsive episode ": 338.5070124109697, "Infantile apnoea ": 66.37719253618003, "Infection susceptibility increased ": 13.66316826374963, "Injection site erythema ": 2.9684648264043227, "Intussusception ": 55.15840141036647, "Irritability ": 18.34744521629333, "Irritability postvaccinal ": 17.769163721857655, "Kawasaki's disease ": 124.2521410591262, "Language disorder ": 8.110883309480084, "Lethargy ": 3.595380299708533, "Meningitis ": 12.069120941351851, "Motor developmental delay ": 65.78443483083953, "Movement disorder ": 3.71586303580453, "Muscle rigidity ": 3.3394778109955543, "Muscle twitching ": 2.712241082834932, "Myoclonus ": 2.5149029554247417, "Neurodermatitis ": 43.20443839174434, "Otitis media ": 39.20311069576132, "Oxygen saturation decreased ": 3.1822942090515136, "Pallor ": 16.2490572949061, "Partial seizures ": 8.957637840918013, "Personality change ": 8.903119479406502, "Petechiae ": 4.410442287899118, "Product administered to patient of inappropriate age ": 7.266874030610229, "Psychomotor hyperactivity ": 4.009263813939239, "Psychomotor skills impaired ": 17.122759786610846, "Pyrexia ": 4.547503932083949, "Rash macular ": 3.2695746057557087, "Rash morbilliform ": 2.5648335564520037, "Reaction to excipient ": 16.409262317848658, "Respiratory tract infection ": 2.5450952612485733, "Restlessness ": 12.655303947558858, "Resuscitation ": 21.22073000274764, "Rhinitis ": 3.098262815554304, "Salivary hypersecretion ": 5.1017441654748, "Scratch ": 19.85438928934217, "Screaming ": 62.76401516082001, "Seizure ": 4.902542556980155, "Skin wound ": 51.72130811301144, "Sleep disorder ": 2.541040451407707, "Somnolence ": 2.392150133856682, "Speech disorder developmental ": 32.63828990591097, "Staring ": 25.64488051212008, "Strabismus ": 22.238659704767255, "Subdural haematoma ": 2.6638136590822263, "Sudden infant death syndrome ": 73.72642031541899, "Type 1 diabetes mellitus ": 11.772646214845746, "Unresponsive to stimuli ": 5.445338220164914, "Urticaria ": 3.309462328152583, "Vaccination complication ": 31.808213504448755, "Vaccination site granuloma ": 141.45240558382972, "Vaccination site oedema ": 4.47265674319959, "Vaccination site pruritus ": 3.633828503933065, "Vaccination site reaction ": 4.933438120595101, "Vaccination site swelling ": 3.555226572751404, "Viral infection ": 4.231417485719541, "Vomiting ": 2.449866841673861, "Vomiting projectile ": 15.627793947683672}
\ No newline at end of file
+{"Application site erythema": 46.69466124977386, "Application site scab": 494.9731889743321, "Blister": 5.029351794573634, "Burning sensation": 4.472287690951847, "Erythema": 6.580664062918335, "Erythema multiforme": 25.1010419806324, "Haemorrhage": 2.700703525230742, "Inflammation": 13.302927383509914, "Influenza like illness": 2.977177588933304, "Oedema": 8.075763175232542, "Off label use": 4.944004105553149, "Scab": 108.97495332841127, "Skin abrasion": 54.20172693234086, "Skin erosion": 174.81077875704233, "Skin exfoliation": 9.383746553014925, "Skin lesion": 11.612426866497596, "Skin reaction": 15.8383975256756, "Skin ulcer": 13.926701525783388, "Skin weeping": 219.5377969668076, "Ulcer": 44.77487349557784}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/568.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/568.json
index a768dbc32c8..26d96ff9119 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/568.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/568.json
@@ -1 +1 @@
-{"Alopecia ": 2.6576386657225, "Anaemia ": 5.254295068611745, "Decreased appetite ": 2.839799559386033, "Depression ": 5.808101471663663, "Influenza like illness ": 2.3352455434726824, "Insomnia ": 2.2877596567567324, "Leukopenia ": 7.973762124647253, "Neutropenia ": 4.776097260006367, "Product complaint ": 19.630874306222, "Red blood cell count decreased ": 16.823621327997, "Therapy non-responder ": 18.697310855265982, "Thrombocytopenia ": 3.1362576476082125, "Weight decreased ": 2.171061607762524, "White blood cell count decreased ": 5.945902781266676}
\ No newline at end of file
+{"Anaemia": 2.505392995944377, "Cardiac failure": 4.582938473039984, "Disease progression": 5.613114123184182, "Febrile neutropenia": 5.969290767559164, "General physical health deterioration": 2.60347905363697, "Infection": 3.7309862787241928, "Interstitial lung disease": 4.273957163611622, "Neutropenia": 14.76242585727813, "Pancytopenia": 10.900286304644728, "Plasma cell myeloma": 88.85475027703849, "Pneumonia": 3.680344077622951, "Rash maculo-papular": 4.417619662793072, "Sepsis": 4.741339880811824, "Thrombocytopenia": 10.066054051577042}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/569.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/569.json
index 6a674581ab7..7fef130be20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/569.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/569.json
@@ -1 +1 @@
-{"Anal fissure ": 100.29983673199862, "Arthritis ": 3.0635623332367925, "Blood pressure fluctuation ": 22.165841597516543, "Blood pressure increased ": 2.451239420858565, "Bronchitis ": 5.665876066326844, "Clostridium difficile infection ": 16.397941931901922, "Colitis ": 3.91428327995926, "Colitis ulcerative ": 18.59168631025018, "Condition aggravated ": 7.720722115430031, "Constipation ": 3.1532467897573757, "Crohn's disease ": 17.075798827570043, "Drug hypersensitivity ": 3.279135469330865, "Drug ineffective ": 2.6136015809108284, "Frequent bowel movements ": 14.505363748733272, "Haematochezia ": 10.800432444208164, "Heart rate decreased ": 10.545648607614371, "Inappropriate schedule of product administration ": 3.60955537663064, "Influenza ": 2.471487595632349, "Intentional product use issue ": 7.615369493215052, "Joint swelling ": 2.018960404184452, "Lower respiratory tract infection ": 7.39735095172084, "Lung disorder ": 3.76549353786466, "Nasopharyngitis ": 3.1595228284850534, "Off label use ": 4.126173577173912, "Oropharyngeal pain ": 3.66686313794112, "Product use issue ": 5.035902344249279, "Rectal haemorrhage ": 6.27393944234994, "Stress ": 5.449502028288671, "Therapeutic product effect incomplete ": 3.278875107376798, "Treatment failure ": 2.252093557539527, "Weight decreased ": 3.799326732341453, "Weight increased ": 5.372777792898541}
\ No newline at end of file
+{"Cough": 9.19712386966158, "Death": 2.4906504656237733, "Device issue": 63.90759022640978, "Dyskinesia": 22.129918832832896}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/57.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/57.json
index bd7595a90bd..c23a7a927d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/57.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/57.json
@@ -1 +1 @@
-{"Weight decreased ": 4.626743628226365}
\ No newline at end of file
+{"Acute hepatic failure": 85.13577901866176, "Cephalhaematoma": 4682.721906056164, "Crying": 15.515090601428962, "Depression": 3.773920480370724, "Drug abuse": 11.680945098091678, "Drug interaction": 4.003843311249107, "Encephalopathy": 35.93279451767134, "Menopausal symptoms": 173.7794336599358, "Metal poisoning": 1080.051204159216, "Product use in unapproved indication": 6.209607709185447, "Rhabdomyolysis": 17.955012444715173, "Self-injurious ideation": 198.9899244718566, "Weight increased": 4.076698886255223}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/570.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/570.json
index f571a996831..a167b40bc0c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/570.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/570.json
@@ -1 +1 @@
-{"Acne ": 3.6345063142172536, "Adverse event ": 2.9043522442495178, "Anal incontinence ": 6.970024780586294, "Angioplasty ": 39.68660109588753, "Autoimmune colitis ": 43.81774354727842, "Blood pressure fluctuation ": 13.07389755788197, "Blood pressure systolic decreased ": 19.546202951258667, "C-reactive protein increased ": 2.863773975197051, "Candida infection ": 3.014747463427676, "Clostridium difficile infection ": 7.677456660242504, "Colitis ": 26.41931226093608, "Colitis ulcerative ": 43.56200922035162, "Condition aggravated ": 4.073503342736783, "Crohn's disease ": 21.018014706016675, "Cytomegalovirus colitis ": 71.0134433706757, "Cytomegalovirus infection ": 6.990865477225045, "Cytomegalovirus viraemia ": 11.528473410068775, "Decreased activity ": 54.36259970695628, "Diarrhoea haemorrhagic ": 4.994576768371735, "Disease recurrence ": 2.0283104752341763, "Disseminated tuberculosis ": 55.729912374370784, "Diverticulitis ": 3.4099816299741588, "Drug hypersensitivity ": 4.842428104319109, "Drug ineffective ": 3.081530684620024, "Drug ineffective for unapproved indication ": 7.123284978221578, "Drug intolerance ": 2.402137436519203, "Drug level above therapeutic ": 17.692189066382436, "Drug level decreased ": 24.54791871576932, "Drug specific antibody present ": 50.01696414162971, "Duodenitis ": 19.40263865414012, "Faecal calprotectin increased ": 44.399033910541874, "Faeces soft ": 30.192664472519443, "Flushing ": 2.207674021690632, "Frequent bowel movements ": 35.87700965493708, "Haematochezia ": 6.751309300719136, "Haemophagocytic lymphohistiocytosis ": 7.166093809176325, "Heart rate decreased ": 2.120600863498509, "Heart rate irregular ": 2.335261497722776, "Hepatosplenic T-cell lymphoma ": 320.4286824637925, "Immune reconstitution inflammatory syndrome ": 8.846545418432335, "Immune-mediated enterocolitis ": 15.64998902019602, "Inappropriate schedule of product administration ": 2.141386733512766, "Incorrect product administration duration ": 4.645671658960571, "Infrequent bowel movements ": 47.003772984888606, "Infusion related reaction ": 2.560179316215295, "Intentional product use issue ": 3.194968426746589, "Interstitial lung disease ": 2.5614844002876835, "Intestinal obstruction ": 6.1868306263258, "Latent tuberculosis ": 38.66918822824572, "Loss of libido ": 9.51673247549562, "Lower respiratory tract infection ": 2.406097792199618, "Metastases to liver ": 3.302205441203484, "Metastases to lung ": 3.9776823642643135, "Mouth ulceration ": 4.513483320089829, "Off label use ": 3.729482984703779, "Pancreatitis ": 2.671741040550064, "Pneumocystis jirovecii pneumonia ": 4.5489797844148745, "Pneumonitis ": 4.943794564730101, "Poor venous access ": 31.750527756816943, "Premature baby ": 2.1480779669871533, "Premature delivery ": 3.81408163964804, "Product use in unapproved indication ": 2.17179998331792, "Product use issue ": 5.283887379814758, "Psoriasis ": 4.077207811533406, "Pulmonary tuberculosis ": 18.702202370765622, "Rectal haemorrhage ": 17.368947854851182, "Tachyphrenia ": 35.54190639486685, "Takayasu's arteritis ": 135.00071655905907, "Therapeutic product effect incomplete ": 2.1393000337192074, "Therapeutic response decreased ": 4.048022666873796, "Therapy non-responder ": 3.5649675891777286, "Treatment failure ": 6.058111303742765, "Tuberculosis ": 9.124205567711488, "Weight increased ": 2.8641792532595662}
\ No newline at end of file
+{"Abscess": 2.1076322238246754, "Acute generalised exanthematous pustulosis": 2.700346096947215, "Acute respiratory distress syndrome": 2.0402518939352268, "Anaemia": 32.273498398476804, "Anal abscess": 11.879287286122594, "Anal fissure": 11.846661823899442, "Anal haemorrhage": 13.15985497548179, "Anal pruritus": 156.10212426211726, "Anorectal discomfort": 47.329415359232186, "Anorectal disorder": 69.15428657856077, "Aphthous ulcer": 3.3777359831663016, "Aplastic anaemia": 4.699734438463656, "Ascites": 6.281502988457305, "Asthenia": 2.513229056839333, "Bacteraemia": 2.582092121152389, "Blood bilirubin increased": 2.1171747402475107, "Blood creatinine abnormal": 5.753007920460614, "Blood creatinine increased": 3.3260236428981806, "Blood thyroid stimulating hormone increased": 5.017106699976378, "Blood uric acid increased": 10.641717064275609, "Bone marrow failure": 6.5768804494509565, "Cholecystitis acute": 6.322766785277191, "Cutaneous vasculitis": 2.1099434692166, "Decreased appetite": 2.7997362268472403, "Depression": 3.332999509911333, "Dermatitis": 4.768386329012486, "Dermatitis bullous": 3.1527492325868445, "Dermatitis exfoliative generalised": 5.134749339016444, "Drug eruption": 3.0433723786696665, "Drug reaction with eosinophilia and systemic symptoms": 13.481308793054993, "Dry skin": 4.504093809964141, "Eczema": 3.3150302754689247, "Emotional disorder": 2.001472889594369, "Encephalopathy": 4.113972515939547, "Eosinophilia": 4.810070668988482, "Erysipelas": 3.220784653708336, "Erythema multiforme": 3.1874541747312883, "Escherichia bacteraemia": 22.441856504678576, "Face oedema": 4.428952767510319, "Food aversion": 9.583655957208135, "Furuncle": 5.748901220733634, "Gastroenteritis": 3.7179323155082935, "Gastrointestinal necrosis": 11.24826156720184, "General physical health deterioration": 2.3380470882666584, "Gingival bleeding": 2.909971761452355, "Gingivitis": 3.012246640751563, "Haematocrit decreased": 2.9023747322074533, "Haemoglobin decreased": 11.314917350879831, "Haemolytic anaemia": 2.962167094576873, "Haemorrhoidal haemorrhage": 17.434684076443634, "Haemorrhoids": 20.332976185088366, "Hepatic cirrhosis": 8.140975922628007, "Hepatic encephalopathy": 3.016371032849432, "Hepatic failure": 3.059422955011196, "Hepatitis C": 2.138588627408528, "Hepatocellular carcinoma": 2.581830366445286, "Hyperbilirubinaemia": 2.2880024339723497, "Hyperthermia": 3.2305144162995467, "Hypertriglyceridaemia": 3.9926395481990777, "Hyperuricaemia": 14.17020391769327, "Leukopenia": 6.723059322709475, "Liver transplant": 19.206452201029723, "Lymphadenopathy mediastinal": 14.850550416853643, "Lymphopenia": 2.871220037072409, "Mental disorder": 2.429141203861877, "Mood swings": 3.250206722718535, "Multiple organ dysfunction syndrome": 3.2953642402732037, "Neutropenia": 4.545852832750631, "Oedema": 2.2834940836454782, "Oedema peripheral": 2.2919399201885127, "Oral candidiasis": 3.4666639284750143, "Oral disorder": 2.899656222909162, "Oral pain": 2.1455777641952323, "Otitis media": 4.32768758828345, "Pancreatitis acute": 3.8287733213352526, "Pancytopenia": 7.725414422896303, "Panniculitis": 4.639197831916441, "Platelet count decreased": 3.2438189480513557, "Portal vein thrombosis": 3.664772253673176, "Proctalgia": 58.57944069348382, "Proctitis": 3.2245793420937776, "Pruritus": 4.195267170543095, "Pustule": 3.872909193914136, "Rash": 7.5341977676162575, "Rash erythematous": 2.3890673200387718, "Rash maculo-papular": 5.180607521132699, "Rectal haemorrhage": 4.506706422843994, "Rectal tenesmus": 33.8738037951446, "Respiratory tract infection": 2.2636438948909268, "Sarcoidosis": 4.3545107438653625, "Sepsis": 3.3123445004683165, "Septic shock": 4.183588544990558, "Skin lesion": 3.320614504559782, "Skin reaction": 7.345750598595121, "Spontaneous bacterial peritonitis": 42.50509988842207, "Staphylococcal sepsis": 15.72155269759164, "Thrombocytopenia": 7.665004305183023, "Toxic skin eruption": 13.5481835008529, "Transfusion": 3.2554820930583794, "Treatment noncompliance": 2.0318202868733697, "Urinary tract infection": 2.421747718299109, "Urosepsis": 5.3671494703549625, "Varices oesophageal": 7.966398189541869, "Viral load increased": 13.896632287420111, "Virologic failure": 5.280518751635785, "Weight decreased": 2.4820348469567324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/571.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/571.json
index 4dbf2808490..111bf346676 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/571.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/571.json
@@ -1 +1 @@
-{"Abdominal wall haematoma ": 81.90071154690648, "Application site pain ": 5.42111609672694, "Contusion ": 2.633901748787585, "Deep vein thrombosis ": 5.571379507893011, "Device issue ": 27.629176552394394, "Epistaxis ": 3.237120882360976, "Erythema ": 6.148474662075424, "Haematoma ": 23.664258543389558, "Haemorrhage ": 3.5419532050873657, "Heparin-induced thrombocytopenia ": 33.89343939392273, "Hypersensitivity ": 2.4097060858785486, "Injection site bruising ": 30.02566080062492, "Injection site erythema ": 2.801516410221856, "Injection site haematoma ": 21.13499359018867, "Injection site haemorrhage ": 25.271097339249344, "Injection site pain ": 7.797921113324845, "Injection site pruritus ": 9.18505094045733, "Intra-abdominal haematoma ": 194.17758788228116, "Maternal exposure during pregnancy ": 5.327997557508038, "Needle issue ": 146.14435753282967, "Product substitution issue ": 45.58339541123116, "Pruritus ": 4.341809521057824, "Pulmonary embolism ": 5.448588220112636, "Rash ": 2.6103788313799337, "Rash pruritic ": 4.994023248744321, "Thrombocytopenia ": 4.404736777517586, "Urticaria ": 5.099943814448609}
\ No newline at end of file
+{"Adverse drug reaction": 3.8641377412606337, "Aphonia": 4.973774797886219, "Asthma": 7.076449886107372, "Atrial fibrillation": 2.9188191763400178, "Bronchitis": 11.782559220372203, "Cardiac disorder": 2.263635782204124, "Cardiac operation": 7.908916315228619, "Cataract": 3.797578380517582, "Cataract operation": 22.82100302744276, "Chest discomfort": 2.095193880694548, "Choking": 16.182369495033704, "Chronic obstructive pulmonary disease": 44.25154855779144, "Colon cancer": 3.6854887227287287, "Colonoscopy": 68.13562467156547, "Condition aggravated": 2.3389170161476804, "Cough": 5.096534097599724, "Dementia": 2.224813248590635, "Device use error": 32.54899279044496, "Diabetes mellitus": 2.021314823318044, "Dry mouth": 2.0966926661652887, "Dry throat": 5.337692142926777, "Dysphonia": 5.983139677246797, "Dyspnoea": 5.131284657984534, "Dyspnoea exertional": 2.135537577371595, "Dysuria": 3.537017732191505, "Emphysema": 6.027904355666179, "Eye pain": 2.534808443364394, "Fall": 2.709843839920452, "Full blood count abnormal": 7.719024628920669, "Glaucoma": 10.181196200405982, "Hospitalisation": 9.29241578335014, "Ill-defined disorder": 5.66829416162152, "Illness": 3.4209387777808127, "Increased bronchial secretion": 31.689351932243348, "Influenza": 2.1885825963465426, "Intentional underdose": 10.543246415066337, "Intercepted medication error": 73.12638411309189, "Intestinal obstruction": 2.5006485524496425, "Labelled drug-drug interaction medication error": 12.478805454018644, "Loss of personal independence in daily activities": 6.226696659294275, "Lung disorder": 5.439000893572809, "Lung neoplasm malignant": 13.09634456805191, "Macular degeneration": 4.22004828739168, "Micturition disorder": 12.138668609296312, "Multiple allergies": 15.7555353573988, "Nasopharyngitis": 2.213148627779678, "Neoplasm malignant": 3.883804197451501, "Obstructive airways disorder": 4.522496775053304, "Oral candidiasis": 4.793885048519384, "Oxygen saturation decreased": 3.4958928188276768, "Oxygen therapy": 63.59037986865131, "Pneumonia": 7.466126234833232, "Pneumothorax": 10.127286651124235, "Pollakiuria": 2.688744731727493, "Prescribed underdose": 4.582914788213763, "Product complaint": 12.419809605101712, "Product dispensing error": 5.543423532013192, "Product dose omission issue": 7.16727555236977, "Product use in unapproved indication": 4.193899556667789, "Productive cough": 8.02698776465279, "Pulmonary congestion": 10.464569005109356, "Rehabilitation therapy": 48.49524189841461, "Respiratory tract congestion": 12.982931428156302, "Respiratory tract infection": 9.707100258518134, "Rhinorrhoea": 2.681956772739372, "Rib fracture": 6.063877870495214, "Secretion discharge": 5.714809058740615, "Sleep apnoea syndrome": 4.354449121455521, "Sleep disorder due to a general medical condition": 18.40221145482263, "Spinal fracture": 3.305484729785217, "Sputum discoloured": 13.311410504466622, "Sputum increased": 18.44765925060612, "Staphylococcal infection": 2.921068007709645, "Stent placement": 6.058443078894984, "Surgery": 4.124536575893146, "Therapeutic product effect incomplete": 6.216511012375739, "Throat irritation": 4.328323319820536, "Underdose": 9.472191046330677, "Urinary retention": 8.69593521411426, "Viral infection": 3.357708832804083, "Vision blurred": 2.329794543574881, "Wheezing": 10.93235280336004, "Wrong technique in device usage process": 24.373815622404315}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/572.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/572.json
index 28ec214c4ec..a47713f211e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/572.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/572.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 2.188402574626931, "Adrenal insufficiency ": 4.534322146058072, "Aphonia ": 12.147411688353444, "Autoimmune colitis ": 14.635524403602489, "Autoimmune hepatitis ": 2.383035737460913, "Blood calcium increased ": 3.3685091442003534, "Blood magnesium decreased ": 2.6643968558096285, "Blood potassium decreased ": 2.0215899822768413, "Blood potassium increased ": 2.862009334960658, "Blood pressure abnormal ": 4.108001222802455, "Blood pressure diastolic increased ": 4.925452566458702, "Blood pressure fluctuation ": 2.1288792481236265, "Blood pressure increased ": 5.947618298117494, "Blood sodium decreased ": 2.060608542929566, "Blood thyroid stimulating hormone increased ": 8.392077989410666, "Body surface area decreased ": 124.65937704731576, "Brain oedema ": 3.067305344091216, "Cancer pain ": 10.024317565636322, "Cardiac dysfunction ": 5.371599943587871, "Cardiac failure ": 2.5832122959487305, "Cerebral infarction ": 2.7667693661497403, "Cholecystitis ": 2.0777545468485665, "Colitis ": 2.0752499209956072, "Constipation ": 2.5310237631883075, "Death ": 4.491724882374365, "Decreased appetite ": 4.185735504711374, "Decreased immune responsiveness ": 2.0287432523324465, "Dehydration ": 4.082085413099716, "Diarrhoea ": 3.79978235941138, "Disease progression ": 13.20255485817898, "Dry skin ": 4.9808813461295225, "Dysphonia ": 16.57617538578399, "Eating disorder ": 3.904834383043246, "Enterocolitis ": 2.7525149917432192, "Faeces soft ": 2.982929618361298, "Feeding disorder ": 4.713536244005971, "Gait inability ": 2.51551395858585, "Gallbladder disorder ": 2.248766413252454, "Gastrointestinal perforation ": 8.656871112969979, "Gingival pain ": 2.2301662877538724, "Glossitis ": 4.033188573388499, "Haemoptysis ": 2.5164452478470167, "Haemorrhage urinary tract ": 4.709692375194555, "Hepatic cytolysis ": 2.0731826563986324, "Hepatic enzyme abnormal ": 3.9921451382715145, "Hepatitis ": 2.2156750662270026, "Hepatotoxicity ": 5.658952619078822, "Hernia ": 2.3519276551861603, "Hypercalcaemia ": 2.340213581533172, "Hyperkeratosis ": 15.080731101288189, "Hypersomnia ": 2.319976162969021, "Hypertension ": 7.93588981525814, "Hypertensive crisis ": 4.1559687576192905, "Hyperthyroidism ": 5.269074920036991, "Hypertransaminasaemia ": 4.049740849509499, "Hypophagia ": 2.5742421675407163, "Hypothyroidism ": 12.046258491430343, "Immune-mediated enterocolitis ": 2.363354522636749, "Immune-mediated hepatic disorder ": 23.705167993430408, "Immune-mediated hypothyroidism ": 6.001825255850177, "Impaired healing ": 2.0935331175948053, "Intestinal perforation ": 5.772307478231756, "Liver function test increased ": 2.2025627045203127, "Localised infection ": 2.178475339739858, "Malignant neoplasm progression ": 2.3582650129712976, "Metastatic renal cell carcinoma ": 57.561952567542654, "Mucosal inflammation ": 3.990599265402368, "Myasthenia gravis ": 2.257196993466269, "Near death experience ": 2.3266356243307924, "Neoplasm malignant ": 2.5454735328346323, "Neoplasm progression ": 46.8356640027241, "Nephrectomy ": 24.85979703431633, "Nephritis ": 3.373467730099228, "Nephrotic syndrome ": 4.631625972329708, "Oesophageal pain ": 4.114298365017184, "Off label use ": 3.3714905858076527, "Oral discomfort ": 2.357684248620034, "Oral disorder ": 2.5187622762524584, "Oral mucosal blistering ": 4.531119554012507, "Oral pain ": 7.741015213140715, "Osteonecrosis of jaw ": 3.691279153893254, "Palmar-plantar erythrodysaesthesia syndrome ": 12.875761466754383, "Physical deconditioning ": 2.158643434180084, "Pneumothorax ": 3.533393888891544, "Polycythaemia ": 11.72398820540779, "Posterior reversible encephalopathy syndrome ": 16.298877596549946, "Product dose omission in error ": 6.142552611668178, "Product dose omission issue ": 2.213373962589314, "Protein urine present ": 8.561011414028785, "Proteinuria ": 11.840970594423409, "Pulmonary oedema ": 2.052953699506774, "Pulmonary thrombosis ": 2.2595050961575143, "Renal cancer ": 13.607273977950364, "Renal cancer metastatic ": 32.32716797200273, "Renal cell carcinoma ": 24.345961508837025, "Renal disorder ": 2.2510065042937533, "Renal haemorrhage ": 12.302893054259268, "Renal impairment ": 2.833168672391469, "Renal mass ": 8.194431613520164, "Second primary malignancy ": 21.67308190083684, "Skin exfoliation ": 2.672777614972349, "Skin lesion ": 2.9740811126629665, "Skin toxicity ": 2.576019913306245, "Sluggishness ": 2.5229841517033065, "Stomatitis ": 8.62823276822617, "Taste disorder ": 2.7504690893114296, "Thrombosis ": 2.1400664587322344, "Thyroid disorder ": 6.51713019786418, "Thyroiditis ": 9.683328444485342, "Tongue discomfort ": 2.858204674806904, "Tongue disorder ": 4.118691375170656, "Tubulointerstitial nephritis ": 2.1842972752489462, "Tumour haemorrhage ": 4.658695431419001, "Type 1 diabetes mellitus ": 4.835605421252635, "Weight decreased ": 4.746617401481346}
\ No newline at end of file
+{"Alopecia": 2.045855905600176, "Anaemia": 2.7213039670509187, "General physical health deterioration": 2.6485928680290987, "Hepatic function abnormal": 5.055162197363615, "Hyperbilirubinaemia": 15.098558188528974, "Hyperlipidaemia": 33.96573037562357, "Hypertriglyceridaemia": 28.139140514324016, "Immune reconstitution inflammatory syndrome": 37.928620840209845, "Lactic acidosis": 10.615151331617422, "Lipoatrophy": 131.48348004087248, "Lipodystrophy acquired": 138.6639156308147, "Nephrolithiasis": 6.732413576584092, "Osteonecrosis": 2.0354347674550377, "Pancreatitis": 3.195000741685373, "Progressive multifocal leukoencephalopathy": 79.22306257314399, "Urinary tract infection": 2.3910834119170024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/573.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/573.json
index 634b878bbff..75f42c43d4d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/573.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/573.json
@@ -1 +1 @@
-{"Blood lactic acid increased ": 140.35975034671853, "Hypokalaemia ": 21.139591143737825, "Hypomagnesaemia ": 132.8584058253871, "Lipase increased ": 81.7024835845914, "Neutrophil count decreased ": 17.38095976171305, "Platelet count decreased ": 9.363497786150964}
\ No newline at end of file
+{"Abnormal behaviour": 2.6070964307545883, "Abnormal faeces": 4.7365412803820215, "Allergy to metals": 68.33082693779392, "Apathy": 6.97649788629731, "Apnoea": 42.26384642761485, "Attention deficit hyperactivity disorder": 11.203989528457498, "Autism spectrum disorder": 28.12897226244677, "Bradycardia": 2.0216463501166184, "Bronchiolitis": 14.623405018478556, "Bronchitis": 4.792786423282139, "Conjunctivitis": 6.216057018745153, "Crying": 39.1497193301867, "Cyanosis": 11.90349966003483, "Dermatitis atopic": 28.100623535048165, "Developmental delay": 31.41941235395304, "Dyskinesia": 3.4374250120919583, "Ear infection": 4.699601217103091, "Eczema": 2.3981527868361106, "Encephalopathy": 2.25666709519876, "Epilepsy": 3.900284836279887, "Eye movement disorder": 17.36099878463675, "Febrile convulsion": 80.98142815718089, "Flatulence": 2.259873552504024, "Food allergy": 6.37120734022315, "Gastroenteritis": 11.904862449586364, "Gaze palsy": 16.670475127604053, "Generalised tonic-clonic seizure": 3.984424650539563, "Haematochezia": 6.5645875543084005, "High-pitched crying": 392.15024004063065, "Hyperpyrexia": 76.74711253996689, "Hypertonia": 11.751743295801267, "Hyporesponsive to stimuli": 28.803101408203595, "Hypotonia": 29.238684109667965, "Hypotonic-hyporesponsive episode": 338.5070124109697, "Infantile apnoea": 66.37719253618003, "Infection susceptibility increased": 13.65320421868539, "Injection site erythema": 2.9684648264043227, "Intussusception": 55.15840141036647, "Irritability": 18.346563844208774, "Irritability postvaccinal": 17.769163721857655, "Kawasaki's disease": 123.9690523837094, "Language disorder": 8.110883309480084, "Lethargy": 3.595380299708533, "Meningitis": 12.069120941351851, "Motor developmental delay": 65.78443483083953, "Movement disorder": 3.71586303580453, "Muscle rigidity": 3.3394778109955543, "Muscle twitching": 2.712241082834932, "Myoclonus": 2.5149029554247417, "Neurodermatitis": 43.20443839174434, "Otitis media": 39.20311069576132, "Oxygen saturation decreased": 3.1821238159542022, "Pallor": 16.248024420691035, "Partial seizures": 8.957637840918013, "Personality change": 8.903119479406502, "Petechiae": 4.410442287899118, "Product administered to patient of inappropriate age": 7.266874030610229, "Psychomotor hyperactivity": 4.008571072691341, "Psychomotor skills impaired": 17.122759786610846, "Pyrexia": 4.547406671464395, "Rash macular": 3.2695746057557087, "Rash morbilliform": 2.5648335564520037, "Reaction to excipient": 16.409262317848658, "Respiratory tract infection": 2.5450952612485733, "Restlessness": 12.654633772801732, "Resuscitation": 21.22073000274764, "Rhinitis": 3.098262815554304, "Salivary hypersecretion": 5.099259990471248, "Scratch": 19.85438928934217, "Screaming": 62.76401516082001, "Seizure": 4.901998258117263, "Skin wound": 51.72130811301144, "Sleep disorder": 2.541040451407707, "Somnolence": 2.392123746797615, "Speech disorder developmental": 32.63828990591097, "Staring": 25.64488051212008, "Strabismus": 22.238659704767255, "Subdural haematoma": 2.6638136590822263, "Sudden infant death syndrome": 73.72642031541899, "Type 1 diabetes mellitus": 11.772646214845746, "Unresponsive to stimuli": 5.444738632450036, "Urticaria": 3.3094283877462174, "Vaccination complication": 31.808213504448755, "Vaccination site granuloma": 141.45240558382972, "Vaccination site oedema": 4.47265674319959, "Vaccination site pruritus": 3.633828503933065, "Vaccination site reaction": 4.933160307665346, "Vaccination site swelling": 3.555226572751404, "Viral infection": 4.231417485719541, "Vomiting": 2.4498337690534417, "Vomiting projectile": 15.627793947683672}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/574.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/574.json
index 0ce3704e74a..21fb828a439 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/574.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/574.json
@@ -1 +1 @@
-{"Decreased appetite ": 3.7480879578302377, "Drug interaction ": 8.671785254443266, "Epilepsy ": 11.840997356961102, "Osteoporosis ": 7.736049387581538, "Seizure ": 10.8738292992694, "Somnolence ": 8.28225396259289, "Status epilepticus ": 67.63086970948213, "Upper limb fracture ": 74.45402310349861, "Vomiting ": 2.055071631591986}
\ No newline at end of file
+{"Alopecia": 2.6576386657225, "Anaemia": 5.254295068611745, "Decreased appetite": 2.8397720147764605, "Depression": 5.808101471663663, "Influenza like illness": 2.3352455434726824, "Insomnia": 2.2877596567567324, "Leukopenia": 7.972756984818838, "Neutropenia": 4.775891878950562, "Product complaint": 19.630874306222, "Red blood cell count decreased": 16.823621327997, "Therapy non-responder": 18.69567700224481, "Thrombocytopenia": 3.1359626363165884, "Weight decreased": 2.171061607762524, "White blood cell count decreased": 5.945902781266676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/575.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/575.json
index 8109fd60a05..debec809bab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/575.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/575.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 6.60193873952468, "Aspartate aminotransferase increased ": 2.0793497300156494, "Blood glucose abnormal ": 19.79542384290868, "Blood glucose decreased ": 12.703666656704058, "Blood glucose fluctuation ": 10.586122428393352, "Blood glucose increased ": 13.3206893187496, "Cholestasis ": 5.684249792751863, "Device issue ": 13.539088830764417, "Device malfunction ": 11.843774814367356, "Diabetes mellitus inadequate control ": 45.73221546366466, "Diabetic ketoacidosis ": 8.997746470177342, "Exposure during pregnancy ": 9.77326085470436, "Fall ": 2.2324037318071643, "Foetal death ": 32.1438997235954, "Foetal exposure during pregnancy ": 8.687319405670058, "Gamma-glutamyltransferase increased ": 5.082973939784116, "Glycosylated haemoglobin increased ": 5.99950847690032, "Hyperglycaemia ": 20.059590601447745, "Hypersensitivity ": 2.18481960960173, "Hypoglycaemia ": 35.31210921510065, "Hypoglycaemia neonatal ": 81.07501212520336, "Hypoglycaemic coma ": 34.002637622298, "Hypoglycaemic unconsciousness ": 40.13525184457348, "Incorrect dose administered by device ": 23.117799935883717, "Injection site pruritus ": 5.926416077490024, "Injection site rash ": 13.398190512472777, "Injection site reaction ": 3.773379391242388, "Lactic acidosis ": 5.741622961994821, "Liquid product physical issue ": 75.28688640571029, "Loss of consciousness ": 2.0698264582768218, "Maternal exposure during pregnancy ": 4.375293189711445, "Neonatal respiratory distress syndrome ": 46.40005896119211, "Premature baby ": 9.6183242895605, "Premature delivery ": 10.524812983759936, "Product quality issue ": 16.843550912533086, "Weight increased ": 5.479049957411704, "Wrong product administered ": 21.98845063315312}
\ No newline at end of file
+{"Anal fissure": 100.14735250984732, "Arthritis": 3.0589052773900134, "Blood pressure fluctuation": 22.13212700151066, "Blood pressure increased": 2.447468511039893, "Bronchitis": 5.656922126567567, "Clostridium difficile infection": 16.373010926433295, "Colitis": 3.9083336774825295, "Colitis ulcerative": 18.563399184532276, "Condition aggravated": 7.708960808412422, "Constipation": 3.1484504594756464, "Crohn's disease": 17.04982339734684, "Drug hypersensitivity": 3.2741488285149907, "Drug ineffective": 2.609600115613739, "Frequent bowel movements": 14.483309116064094, "Haematochezia": 10.782933449898264, "Heart rate decreased": 10.52961376324002, "Inappropriate schedule of product administration": 3.604065592816679, "Influenza": 2.467729003284078, "Intentional product use issue": 7.603786811662298, "Joint swelling": 2.0158909745918474, "Lower respiratory tract infection": 7.38610264072766, "Lung disorder": 3.759769761536471, "Nasopharyngitis": 3.154477697141325, "Off label use": 4.119724094631684, "Oropharyngeal pain": 3.6612861946226434, "Product use issue": 5.028241796894127, "Rectal haemorrhage": 6.264399374177301, "Stress": 5.44121800290882, "Therapeutic product effect incomplete": 3.2738899825837606, "Treatment failure": 2.248670436884821, "Weight decreased": 3.793545161863571, "Weight increased": 5.364602098029566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/576.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/576.json
index 19f017dce18..a02886b1eb7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/576.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/576.json
@@ -1 +1 @@
-{"Accidental overdose ": 2.101898190525938, "Accidental underdose ": 19.67728845955613, "Adverse reaction ": 3.798263650133136, "Altered state of consciousness ": 2.9138140761592437, "Amyloidosis ": 15.648880866836375, "Angina pectoris ": 4.273126204683987, "Anti-GAD antibody positive ": 46.95654069239811, "Anti-insulin antibody ": 105.00069486159164, "Anti-insulin antibody increased ": 102.09304959519568, "Anti-insulin antibody positive ": 86.28165917649825, "Apgar score low ": 5.003405455998516, "Appendicitis ": 2.853004676275869, "Appendicolith ": 5.622198272191772, "Appetite disorder ": 22.9941844941446, "Areflexia ": 6.1074669174394325, "Arterial occlusive disease ": 2.362149686090582, "Bacterial infection ": 2.271366675830864, "Bladder disorder ": 2.5526580182815954, "Blindness ": 3.0215172802751127, "Blindness unilateral ": 2.505773392245206, "Blood glucose abnormal ": 21.827265417373628, "Blood glucose decreased ": 21.955601983491853, "Blood glucose fluctuation ": 39.69045422631204, "Blood glucose increased ": 17.333196207889802, "Blood immunoglobulin E increased ": 3.9168804334622975, "Blood insulin increased ": 47.96976614974731, "Blood pH decreased ": 4.48388198417262, "Blood phosphorus increased ": 4.648412507109309, "Blood pressure systolic increased ": 2.192305886796865, "Body mass index increased ": 8.290560281353107, "Brachial plexopathy ": 26.47057963704047, "Bronchitis chronic ": 12.578460965860348, "Caesarean section ": 3.208071507238475, "Cardiac disorder ": 2.1995237919962856, "Cardiac murmur ": 3.398524815325715, "Cataract ": 3.9344252892003713, "Cataract operation ": 2.0101496829205883, "Cerebral ischaemia ": 2.0049403640211523, "Cerebral reperfusion injury ": 329.25075376844046, "Cholecystectomy ": 2.0347121735245906, "Chorea ": 5.568995500261613, "Cold sweat ": 2.8806103720428613, "Coronary artery occlusion ": 2.3730297095250528, "Coronary artery stenosis ": 2.615328110325524, "Cutaneous amyloidosis ": 166.41215052670933, "Cystitis interstitial ": 35.506549893734444, "Dementia ": 2.494178632942804, "Dementia Alzheimer's type ": 2.6365960210117487, "Depressed mood ": 2.7271226463845624, "Depressive symptom ": 20.04622772029776, "Device breakage ": 3.172652224313855, "Device defective ": 5.845063826092957, "Device issue ": 6.8122418767389314, "Device operational issue ": 15.366393445326151, "Device use issue ": 6.406533331932971, "Diabetes mellitus inadequate control ": 31.442923526123764, "Diabetic coma ": 11.622247042035267, "Diabetic complication ": 21.564700287283827, "Diabetic foot ": 27.47775794054949, "Diabetic ketoacidosis ": 11.00435716352555, "Diabetic metabolic decompensation ": 51.32322129283153, "Diabetic nephropathy ": 8.100042622105011, "Diabetic neuropathy ": 11.159458266655582, "Diabetic retinopathy ": 23.70068762808112, "Disorganised speech ": 3.6206086184757336, "Drug administered in wrong device ": 77.0786016108551, "Drug hypersensitivity ": 3.079063954170403, "Drug level below therapeutic ": 4.4286373594416375, "Dyspnoea exertional ": 3.236672286225232, "Erosive duodenitis ": 12.2897902084719, "Expired product administered ": 2.055255835664574, "Exposure during pregnancy ": 2.387463909358403, "Extra dose administered ": 5.332506304324538, "Eye haemorrhage ": 3.907672788597859, "Fall ": 2.0273065221002917, "Flank pain ": 13.799449972360543, "Foetal exposure during pregnancy ": 3.861844136446433, "Foetal exposure timing unspecified ": 17.037506530249967, "Foetal growth restriction ": 4.790996153703854, "Gangrene ": 6.018093249937285, "Gastrointestinal carcinoma ": 3.92895532668363, "Generalised oedema ": 2.0070549406194624, "Gestational hypertension ": 13.986377020703872, "Glycosylated haemoglobin abnormal ": 8.60139676029587, "Glycosylated haemoglobin decreased ": 17.15085704601116, "Glycosylated haemoglobin increased ": 26.81431476333669, "Heart sounds ": 509.0377309557073, "Hemiplegia ": 2.599733034444483, "Hepatomegaly ": 2.3767663923348072, "Hunger ": 9.04618132070707, "Hyperglycaemia ": 21.228420769716006, "Hyperinsulinaemia ": 27.491114252306765, "Hyperinsulinaemic hypoglycaemia ": 26.22679902043395, "Hypoglycaemia ": 38.39556059638405, "Hypoglycaemia neonatal ": 51.74019821807413, "Hypoglycaemia unawareness ": 36.93383428644884, "Hypoglycaemic coma ": 41.795373610938746, "Hypoglycaemic encephalopathy ": 39.83663393846316, "Hypoglycaemic seizure ": 20.139371009611352, "Hypoglycaemic unconsciousness ": 30.217602853456096, "Impaired gastric emptying ": 3.4950962604679656, "Incorrect dose administered ": 7.256820448805883, "Incorrect dose administered by device ": 3.615381078273148, "Incorrect product administration duration ": 2.2071278027033023, "Increased appetite ": 3.617582583129311, "Induration ": 2.0574446513412665, "Injection site abscess ": 4.346093497176509, "Injection site atrophy ": 59.3583778629965, "Injection site bruising ": 3.16320127948626, "Injection site discolouration ": 2.850513707230089, "Injection site hypersensitivity ": 2.562349935823217, "Injection site induration ": 3.4630584056725904, "Injection site nodule ": 6.901422013170029, "Injection site urticaria ": 6.974209573713489, "Injury ": 4.161797213186596, "Injury associated with device ": 7.990588753491875, "Insulin C-peptide decreased ": 47.0287744961078, "Insulin C-peptide increased ": 88.05675507795686, "Insulin autoimmune syndrome ": 56.51647284079366, "Insulin resistance ": 46.788192016979416, "Intentional dose omission ": 2.867989424634064, "Intentional overdose ": 2.4416901290381143, "Jaundice neonatal ": 5.945557220737262, "Ketoacidosis ": 10.827389162752286, "Ketosis ": 7.870263036008226, "Left ventricular hypertrophy ": 2.7795099109884123, "Leg amputation ": 5.442274200635206, "Limb injury ": 2.186108042313221, "Lipoatrophy ": 23.663757305543054, "Lipodystrophy acquired ": 5.908147386209165, "Lipohypertrophy ": 17.42416003861978, "Localised infection ": 2.939278886159805, "Loss of consciousness ": 2.562426716071182, "Lower respiratory tract infection ": 3.3552902451283595, "Malnutrition ": 2.1410576600848086, "Maternal exposure before pregnancy ": 3.530598492227121, "Maternal exposure during pregnancy ": 2.608956472803196, "Medication error ": 2.3451829841043774, "Metabolic disorder ": 5.647429494658617, "Metabolic syndrome ": 8.453228637314536, "Microalbuminuria ": 8.421722293891142, "Multi-organ disorder ": 10.693664890472649, "Nasal congestion ": 4.406263090470182, "Onychoclasis ": 3.878152757668662, "Osteomyelitis ": 2.7158868217062246, "Pancreatic disorder ": 2.60432142302513, "Polydipsia ": 7.444265565416608, "Polyuria ": 2.833298156432316, "Post procedural complication ": 2.3076596515599186, "Postprandial hypoglycaemia ": 55.230240255555074, "Pre-eclampsia ": 11.98814642818381, "Premature baby ": 6.539373428793136, "Premature delivery ": 5.361874229152554, "Product dose omission issue ": 2.4047781865307924, "Product monitoring error ": 25.6958108516746, "Product selection error ": 15.763066581367177, "Product storage error ": 7.805098451626654, "Productive cough ": 5.007335850759927, "Prolonged expiration ": 289.7063554763469, "Pulmonary arterial hypertension ": 2.667830054051859, "Pulmonary mass ": 2.9107527809805624, "Rales ": 19.285108807716416, "Renal disorder ": 2.031210828396933, "Respiration abnormal ": 15.38942718038784, "Retinal detachment ": 2.797034573153604, "Retinopathy ": 5.291521094476115, "Rhinorrhoea ": 2.6004735713794456, "Road traffic accident ": 2.294145419942483, "Shock hypoglycaemic ": 11.428123004264917, "Shoulder fracture ": 2.421806964992624, "Skin induration ": 2.5252735423438306, "Skin mass ": 3.798412793941041, "Skin test positive ": 9.396483262519974, "Sleep disorder due to a general medical condition ": 6.922145763030374, "Starvation ": 17.351661479221224, "Stress ": 6.062002751662191, "Suspected suicide ": 4.049623959672664, "Systemic inflammatory response syndrome ": 3.1079166677180976, "Tearfulness ": 2.421532172463406, "Toe amputation ": 5.3542382786218745, "Treatment noncompliance ": 4.472495109248133, "Type 1 diabetes mellitus ": 3.422614382687812, "Type I hypersensitivity ": 5.945508902729597, "Type III immune complex mediated reaction ": 21.882097754320576, "Unresponsive to stimuli ": 3.919987084233172, "Upper respiratory tract infection ": 5.101732254187432, "Urine ketone body present ": 8.979123534650236, "Vascular stent stenosis ": 19.344187943222632, "Visual impairment ": 2.7469159900887696, "Weight decreased ": 2.3738986328777982, "Weight increased ": 3.5900499778113524, "Weight loss poor ": 4.223975719980431, "Wheezing ": 2.13265936460401, "Wrong product administered ": 13.548708694450076, "Wrong technique in product usage process ": 4.567874105726318}
\ No newline at end of file
+{"Acne": 3.6345063142172536, "Adverse event": 2.9043522442495178, "Anal incontinence": 6.970024780586294, "Angioplasty": 39.68660109588753, "Autoimmune colitis": 43.81774354727842, "Blood pressure fluctuation": 13.07389755788197, "Blood pressure systolic decreased": 19.546202951258667, "C-reactive protein increased": 2.863773975197051, "Candida infection": 3.014747463427676, "Clostridium difficile infection": 7.677456660242504, "Colitis": 26.41931226093608, "Colitis ulcerative": 43.56200922035162, "Condition aggravated": 4.073503342736783, "Crohn's disease": 21.018014706016675, "Cytomegalovirus colitis": 71.0134433706757, "Cytomegalovirus infection": 6.990865477225045, "Cytomegalovirus viraemia": 11.528473410068775, "Decreased activity": 54.36259970695628, "Diarrhoea haemorrhagic": 4.994576768371735, "Disease recurrence": 2.0283104752341763, "Disseminated tuberculosis": 55.729912374370784, "Diverticulitis": 3.4099816299741588, "Drug hypersensitivity": 4.842428104319109, "Drug ineffective": 3.081507885542181, "Drug ineffective for unapproved indication": 7.123284978221578, "Drug intolerance": 2.402137436519203, "Drug level above therapeutic": 17.692189066382436, "Drug level decreased": 24.54791871576932, "Drug specific antibody present": 50.01696414162971, "Duodenitis": 19.40263865414012, "Faecal calprotectin increased": 44.399033910541874, "Faeces soft": 30.192664472519443, "Flushing": 2.207674021690632, "Frequent bowel movements": 35.87700965493708, "Haematochezia": 6.750640495113327, "Haemophagocytic lymphohistiocytosis": 7.166093809176325, "Heart rate decreased": 2.120600863498509, "Heart rate irregular": 2.335261497722776, "Hepatosplenic T-cell lymphoma": 320.4286824637925, "Immune reconstitution inflammatory syndrome": 8.846545418432335, "Immune-mediated enterocolitis": 15.64998902019602, "Inappropriate schedule of product administration": 2.141386733512766, "Incorrect product administration duration": 4.645671658960571, "Infrequent bowel movements": 47.003772984888606, "Infusion related reaction": 2.560179316215295, "Intentional product use issue": 3.194968426746589, "Interstitial lung disease": 2.5614844002876835, "Intestinal obstruction": 6.1868306263258, "Latent tuberculosis": 38.66918822824572, "Loss of libido": 9.51673247549562, "Lower respiratory tract infection": 2.406097792199618, "Metastases to liver": 3.302205441203484, "Metastases to lung": 3.9776823642643135, "Mouth ulceration": 4.513483320089829, "Off label use": 3.729335938712632, "Pancreatitis": 2.671741040550064, "Pneumocystis jirovecii pneumonia": 4.5489797844148745, "Pneumonitis": 4.943794564730101, "Poor venous access": 31.750527756816943, "Premature baby": 2.1480779669871533, "Premature delivery": 3.81408163964804, "Product use in unapproved indication": 2.1717322217431403, "Product use issue": 5.283887379814758, "Psoriasis": 4.077207811533406, "Pulmonary tuberculosis": 18.702202370765622, "Rectal haemorrhage": 17.368947854851182, "Tachyphrenia": 35.54190639486685, "Takayasu's arteritis": 135.00071655905907, "Therapeutic product effect incomplete": 2.1393000337192074, "Therapeutic response decreased": 4.048022666873796, "Therapy non-responder": 3.564655946391075, "Treatment failure": 6.058111303742765, "Tuberculosis": 9.124205567711488, "Weight increased": 2.8641792532595662}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/577.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/577.json
index 057b90bd2b9..7df4ccfb1ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/577.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/577.json
@@ -1 +1 @@
-{"Agitation ": 2.8593307225004563, "Blood glucose abnormal ": 32.15073150275138, "Blood glucose decreased ": 11.79215330665054, "Blood glucose fluctuation ": 44.4145866971573, "Blood glucose increased ": 24.24844516194957, "Dermatitis allergic ": 8.394612998488647, "Diabetes mellitus inadequate control ": 21.62515435482284, "Drug ineffective ": 3.0906429195403438, "Hyperglycaemia ": 18.465977341689065, "Hypersensitivity ": 3.874387570730978, "Hypoglycaemia ": 28.73926687814118, "Hypoglycaemic coma ": 35.20144740261754, "Ketoacidosis ": 14.836894349817989, "Loss of consciousness ": 2.26309896866658, "Product complaint ": 8.109223304435012, "Product quality issue ": 8.006479920118634, "Product storage error ": 22.20525235270007, "Pruritus ": 2.445623142025537, "Shock hypoglycaemic ": 565.3150908164297, "Stevens-Johnson syndrome ": 6.057229131990138, "Therapeutic response decreased ": 6.439673970069999}
\ No newline at end of file
+{"Abdominal wall haematoma": 81.90071154690648, "Application site pain": 5.420470806772504, "Contusion": 2.633901748787585, "Deep vein thrombosis": 5.571379507893011, "Device issue": 27.629176552394394, "Epistaxis": 3.237120882360976, "Erythema": 6.148414509688357, "Haematoma": 23.664258543389558, "Haemorrhage": 3.5419532050873657, "Heparin-induced thrombocytopenia": 33.89343939392273, "Hypersensitivity": 2.4097060858785486, "Injection site bruising": 30.02566080062492, "Injection site erythema": 2.801516410221856, "Injection site haematoma": 21.13499359018867, "Injection site haemorrhage": 25.271097339249344, "Injection site pain": 7.7978233782282, "Injection site pruritus": 9.18505094045733, "Intra-abdominal haematoma": 194.17758788228116, "Maternal exposure during pregnancy": 5.327997557508038, "Needle issue": 146.14435753282967, "Product substitution issue": 45.58339541123116, "Pruritus": 4.341756922201499, "Pulmonary embolism": 5.448588220112636, "Rash": 2.6103429720115408, "Rash pruritic": 4.994023248744321, "Thrombocytopenia": 4.404322382511776, "Urticaria": 5.099891554651284}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/578.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/578.json
index 5b4e9091685..8e098d6510a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/578.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/578.json
@@ -1 +1 @@
-{"Acute myocardial infarction ": 3.835703028270673, "Atelectasis ": 13.599422902071366, "Blood creatinine increased ": 2.3902030808793446, "Bradycardia ": 2.885982502303168, "Cardiac arrest ": 3.996731613952982, "Cardiac tamponade ": 35.392869542997, "Cardiogenic shock ": 27.601603830101084, "Cerebral haemorrhage ": 13.394588598119425, "Coronary artery disease ": 5.419246917653654, "Coronary artery occlusion ": 13.338233526765263, "Coronary artery thrombosis ": 179.42443305229153, "Death ": 3.205497284453947, "Depressed level of consciousness ": 2.8342548527553384, "Epistaxis ": 3.374395580793081, "Gastrointestinal haemorrhage ": 7.035055564647983, "Gingival bleeding ": 9.913264867442908, "Haematemesis ": 15.604528776443608, "Haematocrit decreased ": 8.535036944170484, "Haematoma ": 10.763089054217128, "Haematuria ": 9.858123716136872, "Haemoglobin decreased ": 9.765933657006384, "Haemoptysis ": 14.394136447758727, "Haemorrhage ": 21.033080146512084, "Haemorrhage intracranial ": 99.62991781874044, "Haemorrhagic stroke ": 13.3021975125005, "Hyperglycaemia ": 2.135309826814493, "Hypotension ": 5.410222173910755, "Injection site haemorrhage ": 13.002030102046518, "Melaena ": 4.657665409948859, "Meningitis viral ": 96.46591368346768, "Mitral valve incompetence ": 15.995202876832636, "Multiple organ dysfunction syndrome ": 3.976621746033693, "Myocardial infarction ": 6.57120765111645, "Oxygen saturation decreased ": 2.8390676152454493, "Petechiae ": 5.555594037234224, "Platelet count decreased ": 8.6654893868613, "Pleural effusion ": 2.7330007152868947, "Product complaint ": 4.992649438773675, "Pulmonary alveolar haemorrhage ": 36.71392107007821, "Pulmonary haemorrhage ": 40.508386290727714, "Pulmonary oedema ": 5.1737116660134, "Retroperitoneal haemorrhage ": 163.9798936559638, "Shock ": 6.224400534317862, "Thrombocytopenia ": 21.05797244707951, "Thrombosis ": 10.43120476899411, "Thrombosis in device ": 57.21520619148361, "Unresponsive to stimuli ": 7.2337051250587505, "Vascular stent thrombosis ": 27.102178320942453}
\ No newline at end of file
+{"Acute coronary syndrome": 2.188402574626931, "Adrenal insufficiency": 4.534322146058072, "Aphonia": 12.147411688353444, "Autoimmune colitis": 14.635524403602489, "Autoimmune hepatitis": 2.383035737460913, "Blood calcium increased": 3.3685091442003534, "Blood magnesium decreased": 2.6643968558096285, "Blood potassium decreased": 2.0215899822768413, "Blood potassium increased": 2.862009334960658, "Blood pressure abnormal": 4.108001222802455, "Blood pressure diastolic increased": 4.925452566458702, "Blood pressure fluctuation": 2.1288792481236265, "Blood pressure increased": 5.947513200070963, "Blood sodium decreased": 2.060608542929566, "Blood thyroid stimulating hormone increased": 8.392077989410666, "Body surface area decreased": 124.65937704731576, "Brain oedema": 3.067305344091216, "Cancer pain": 10.024317565636322, "Cardiac dysfunction": 5.371599943587871, "Cardiac failure": 2.5829758283844844, "Cerebral infarction": 2.7667693661497403, "Cholecystitis": 2.0777545468485665, "Colitis": 2.0752499209956072, "Constipation": 2.5310237631883075, "Death": 4.491724882374365, "Decreased appetite": 4.185694710334141, "Decreased immune responsiveness": 2.0287432523324465, "Dehydration": 4.081866515781464, "Diarrhoea": 3.799750511817528, "Disease progression": 13.20255485817898, "Dry skin": 4.9808813461295225, "Dysphonia": 16.57617538578399, "Eating disorder": 3.904834383043246, "Enterocolitis": 2.7525149917432192, "Faeces soft": 2.982929618361298, "Feeding disorder": 4.713536244005971, "Gait inability": 2.51551395858585, "Gallbladder disorder": 2.248766413252454, "Gastrointestinal perforation": 8.656871112969979, "Gingival pain": 2.2301662877538724, "Glossitis": 4.033188573388499, "Haemoptysis": 2.5164452478470167, "Haemorrhage urinary tract": 4.709692375194555, "Hepatic cytolysis": 2.0731826563986324, "Hepatic enzyme abnormal": 3.9921451382715145, "Hepatitis": 2.2156750662270026, "Hepatotoxicity": 5.658952619078822, "Hernia": 2.3519276551861603, "Hypercalcaemia": 2.340213581533172, "Hyperkeratosis": 15.080731101288189, "Hypersomnia": 2.319976162969021, "Hypertension": 7.935807145484281, "Hypertensive crisis": 4.1559687576192905, "Hyperthyroidism": 5.268592704605744, "Hypertransaminasaemia": 4.049740849509499, "Hypophagia": 2.5742421675407163, "Hypothyroidism": 12.046258491430343, "Immune-mediated enterocolitis": 2.363354522636749, "Immune-mediated hepatic disorder": 23.705167993430408, "Immune-mediated hypothyroidism": 6.001825255850177, "Impaired healing": 2.0935331175948053, "Intestinal perforation": 5.772307478231756, "Liver function test increased": 2.2025627045203127, "Localised infection": 2.178475339739858, "Malignant neoplasm progression": 2.3582650129712976, "Metastatic renal cell carcinoma": 57.561952567542654, "Mucosal inflammation": 3.990599265402368, "Myasthenia gravis": 2.257196993466269, "Near death experience": 2.3266356243307924, "Neoplasm malignant": 2.5454735328346323, "Neoplasm progression": 46.8356640027241, "Nephrectomy": 24.85979703431633, "Nephritis": 3.373467730099228, "Nephrotic syndrome": 4.631625972329708, "Oesophageal pain": 4.114298365017184, "Off label use": 3.371357286694154, "Oral discomfort": 2.357684248620034, "Oral disorder": 2.5187622762524584, "Oral mucosal blistering": 4.531119554012507, "Oral pain": 7.741015213140715, "Osteonecrosis of jaw": 3.691279153893254, "Palmar-plantar erythrodysaesthesia syndrome": 12.875761466754383, "Physical deconditioning": 2.158643434180084, "Pneumothorax": 3.533393888891544, "Polycythaemia": 11.72398820540779, "Posterior reversible encephalopathy syndrome": 16.298877596549946, "Product dose omission in error": 6.142552611668178, "Product dose omission issue": 2.213373962589314, "Protein urine present": 8.561011414028785, "Proteinuria": 11.840970594423409, "Pulmonary oedema": 2.052683586755159, "Pulmonary thrombosis": 2.2595050961575143, "Renal cancer": 13.607273977950364, "Renal cancer metastatic": 32.32716797200273, "Renal cell carcinoma": 24.345961508837025, "Renal disorder": 2.2506736787228854, "Renal haemorrhage": 12.302893054259268, "Renal impairment": 2.833168672391469, "Renal mass": 8.194431613520164, "Second primary malignancy": 21.67308190083684, "Skin exfoliation": 2.672777614972349, "Skin lesion": 2.9740811126629665, "Skin toxicity": 2.5723262489521312, "Sluggishness": 2.5229841517033065, "Stomatitis": 8.62823276822617, "Taste disorder": 2.7504690893114296, "Thrombosis": 2.1400664587322344, "Thyroid disorder": 6.51713019786418, "Thyroiditis": 9.683328444485342, "Tongue discomfort": 2.858204674806904, "Tongue disorder": 4.118691375170656, "Tubulointerstitial nephritis": 2.1842972752489462, "Tumour haemorrhage": 4.658695431419001, "Type 1 diabetes mellitus": 4.835605421252635, "Weight decreased": 4.746617401481346}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/579.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/579.json
index e0fdc639fac..465627623a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/579.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/579.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 4.546432581542087, "Anaemia ": 2.842822682133357, "Blindness ": 3.709520722607151, "Blood cholesterol increased ": 5.019847277198758, "Blood creatine phosphokinase increased ": 3.475451418412697, "Blood magnesium increased ": 196.05906906058885, "Drug interaction ": 3.205641610300448, "Drug level increased ": 6.767579741795777, "Drug reaction with eosinophilia and systemic symptoms ": 7.953675493072498, "Drug resistance ": 5.547178033788962, "Dysarthria ": 3.421208629107179, "Exposure during pregnancy ": 7.613149553509169, "Eye pain ": 2.7160391488955344, "Foetal exposure during pregnancy ": 10.041149469213378, "Gait disturbance ": 3.419045602104735, "H1N1 influenza ": 147.18136326792742, "Hepatic cirrhosis ": 10.659739972018835, "Hypercholesterolaemia ": 20.331408852927524, "Lipodystrophy acquired ": 57.52824164423886, "Lung lobectomy ": 392.0162968566276, "Maternal exposure during pregnancy ": 4.846197871679369, "Mitochondrial DNA depletion ": 4803.567854497512, "Mitochondrial myopathy acquired ": 1634.87883964271, "Mitochondrial toxicity ": 108.03239645820874, "Mobility decreased ": 2.588487564792472, "Multiple organ dysfunction syndrome ": 3.835737953232934, "Myocardial infarction ": 2.15311431672718, "Nervous system disorder ": 17.010059857792, "Neuropathy peripheral ": 9.49992055615028, "Neurotoxicity ": 19.471394046635037, "Pancreatitis acute ": 3.90052859478247, "Pollakiuria ": 12.124317213615468, "Rash maculo-papular ": 6.353346421745764, "Rash pruritic ": 3.1398908464701853, "Red blood cell count decreased ": 6.131405407137554, "Renal failure ": 2.137193343868846, "Renal tubular disorder ": 36.19940474362985, "Sleep disorder ": 2.466520317712088, "Toxic skin eruption ": 8.470208755337556, "Vitamin B6 deficiency ": 853.9363846056168}
\ No newline at end of file
+{"Blood lactic acid increased": 140.35975034671853, "Hypokalaemia": 21.139591143737825, "Hypomagnesaemia": 132.8584058253871, "Lipase increased": 81.7024835845914, "Neutrophil count decreased": 17.38095976171305, "Platelet count decreased": 9.363497786150964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/58.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/58.json
index 6fefaaed9ca..49c8ac90fee 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/58.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/58.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 5.256692338989005, "Alopecia ": 3.578587789463588, "Altered state of consciousness ": 6.640526091070373, "Aspartate aminotransferase increased ": 6.008725020825621, "Blood alkaline phosphatase increased ": 11.42816061559514, "Blood bilirubin increased ": 9.843290135730951, "Cholestasis ": 19.729984872759196, "Constipation ": 2.518250336260491, "Depressed level of consciousness ": 5.137880036911207, "Drug-induced liver injury ": 9.20669275288271, "Electrocardiogram QT prolonged ": 8.226379892404765, "Febrile neutropenia ": 7.775614210119801, "Haemolysis ": 91.04718887035745, "Hepatic enzyme increased ": 8.90267033169458, "Hypersensitivity ": 2.270165281457616, "Hypokalaemia ": 4.068647694150727, "Hyponatraemia ": 3.203744470085851, "Hypophagia ": 23.469966448367465, "Interstitial lung disease ": 6.442653242552805, "Jaundice ": 15.536059121445389, "Muscle spasms ": 2.592170907969974, "Neutropenia ": 2.164915742137972, "Palmar-plantar erythrodysaesthesia syndrome ": 13.355275236298018, "Wheezing ": 4.280106120179919}
\ No newline at end of file
+{"Weight decreased": 4.626743628226365}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/580.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/580.json
index 5cf3c42a9cc..a737036c0c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/580.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/580.json
@@ -1 +1 @@
-{"Anaemia ": 5.019918709679311, "Depression ": 4.6108796678941, "Haemoglobin decreased ": 3.020494907266305, "Haemolytic anaemia ": 11.715555197298055, "Hepatic cirrhosis ": 8.66354073960194, "Hepatic failure ": 5.082185707007766, "Hyperthyroidism ": 10.791029692140649, "Hypothyroidism ": 9.94358682446966, "Lethargy ": 3.350577336109295, "Neutropenia ": 2.912193502400345, "Pancytopenia ": 2.5271831823825943, "Platelet count decreased ": 2.8186379042981486, "Rash pruritic ": 2.303674630269364, "Sleep disorder ": 2.004626325889361, "Therapy non-responder ": 9.763489066226768, "Weight decreased ": 3.0075023352844235, "White blood cell count decreased ": 3.9589913980705234}
\ No newline at end of file
+{"Decreased appetite": 3.7480516045263728, "Drug interaction": 8.671785254443266, "Epilepsy": 11.840997356961102, "Osteoporosis": 7.736049387581538, "Seizure": 10.872623781914502, "Somnolence": 8.282162662783328, "Status epilepticus": 67.63086970948213, "Upper limb fracture": 74.45402310349861, "Vomiting": 2.0550439106732505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/581.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/581.json
index 8dc257e122c..6ad2c2ec8f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/581.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/581.json
@@ -1 +1 @@
-{"Abortion induced ": 12.54486533736513, "Affect lability ": 10.212844626797075, "Aggression ": 4.181127741410827, "Altered state of consciousness ": 2.092654666118045, "Amnesia ": 2.357081350582774, "Anaemia ": 8.87785976906131, "Ascites ": 5.518125061279705, "Blood lactate dehydrogenase increased ": 2.900355183044035, "Blood thyroid stimulating hormone increased ": 7.019218225295544, "Bronchitis ": 2.483175165673872, "Central venous catheterisation ": 23.25685931960968, "Cerebral haemorrhage ": 4.178954828261928, "Cerebral infarction ": 2.615170887647368, "Cognitive disorder ": 2.153039032474172, "Colitis ischaemic ": 16.695882635023157, "Deafness ": 2.540927256395358, "Decreased appetite ": 4.765611025289888, "Dehydration ": 2.2250388782627497, "Dementia ": 3.0672261014682647, "Depression ": 7.497346323178047, "Depressive symptom ": 15.879332119412894, "Diabetes mellitus ": 7.882482432473407, "Disseminated intravascular coagulation ": 3.195812437602445, "Facial paralysis ": 2.0666796156607155, "Foetal death ": 15.198744649563524, "Gingival bleeding ": 3.262624305993968, "Granulocyte count decreased ": 33.74502690751007, "Granulocytopenia ": 6.9871829463236335, "Haemoglobin decreased ": 4.814137752741623, "Haemolytic anaemia ": 18.447631254296628, "Helicobacter infection ": 2.507787583909556, "Hepatic cirrhosis ": 7.215738714312078, "Hepatic encephalopathy ": 5.475564904564629, "Hepatic failure ": 4.221086457258415, "Hyperthyroidism ": 9.336094731535342, "Hypoacusis ": 3.273474989013229, "Hypoalbuminaemia ": 7.149185188044743, "Hypothyroidism ": 8.604319828204773, "Immune thrombocytopenia ": 3.9606177576914714, "Insomnia ": 2.6949970071165663, "Interstitial lung disease ": 4.567996500738476, "Irritability ": 3.725918475816112, "Jaundice ": 3.0423533520306183, "Leukopenia ": 5.253062487466219, "Mania ": 6.337118613283159, "Mental disorder ": 2.7581073436713144, "Nephrotic syndrome ": 6.62360406406957, "Optic neuritis ": 7.712711717318518, "Pancreatitis ": 2.083909232317406, "Paranoia ": 3.3343337518119984, "Platelet count decreased ": 5.260212542852878, "Pleural effusion ": 2.73668783993894, "Psychotic disorder ": 2.4154655399077165, "Retinal exudates ": 31.436448157819083, "Retinal haemorrhage ": 33.485233373825295, "Retinal vein occlusion ": 15.613812942114516, "Retinopathy ": 33.46814813320723, "Sarcoidosis ": 10.236303744746046, "Subarachnoid haemorrhage ": 4.523764780366626, "Suicidal ideation ": 4.438242023091989, "Suicide attempt ": 3.197394006889928, "Thrombocytopenia ": 3.2386739213754563, "Thyroid disorder ": 3.335622607398148, "Type 1 diabetes mellitus ": 11.643094586855527, "Visual acuity reduced ": 2.6690351352316832, "Visual field defect ": 4.859648416242328, "Weight decreased ": 2.4580696854777937, "White blood cell count decreased ": 3.940577973735394}
\ No newline at end of file
+{"Abortion spontaneous": 6.60193873952468, "Aspartate aminotransferase increased": 2.0793497300156494, "Blood glucose abnormal": 19.79542384290868, "Blood glucose decreased": 12.703666656704058, "Blood glucose fluctuation": 10.586122428393352, "Blood glucose increased": 13.3206893187496, "Cholestasis": 5.684249792751863, "Device issue": 13.539088830764417, "Device malfunction": 11.843774814367356, "Diabetes mellitus inadequate control": 45.73221546366466, "Diabetic ketoacidosis": 8.997746470177342, "Exposure during pregnancy": 9.77326085470436, "Fall": 2.2323464990459, "Foetal death": 32.1438997235954, "Foetal exposure during pregnancy": 8.687319405670058, "Gamma-glutamyltransferase increased": 5.082973939784116, "Glycosylated haemoglobin increased": 5.99950847690032, "Hyperglycaemia": 20.059590601447745, "Hypersensitivity": 2.18481960960173, "Hypoglycaemia": 35.31091219850383, "Hypoglycaemia neonatal": 81.07501212520336, "Hypoglycaemic coma": 34.002637622298, "Hypoglycaemic unconsciousness": 40.13525184457348, "Incorrect dose administered by device": 23.117799935883717, "Injection site pruritus": 5.926416077490024, "Injection site rash": 13.398190512472777, "Injection site reaction": 3.773379391242388, "Lactic acidosis": 5.741622961994821, "Liquid product physical issue": 75.28688640571029, "Loss of consciousness": 2.069725156287737, "Maternal exposure during pregnancy": 4.375293189711445, "Neonatal respiratory distress syndrome": 46.40005896119211, "Premature baby": 9.6183242895605, "Premature delivery": 10.524812983759936, "Product quality issue": 16.843550912533086, "Weight increased": 5.479049957411704, "Wrong product administered": 21.98845063315312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/582.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/582.json
index e52b19ff9a7..96fc8ebf1e9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/582.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/582.json
@@ -1 +1 @@
-{"Adverse drug reaction ": 46.95851037294072, "Anger ": 65.12814380348618, "Brain lobectomy ": 13984.089535116078, "Seizure ": 6.859615562313105}
\ No newline at end of file
+{"Accidental overdose": 2.101248798852428, "Accidental underdose": 19.67120922741212, "Adverse reaction": 3.797090181500917, "Altered state of consciousness": 2.912913779201449, "Amyloidosis": 15.64404638596218, "Angina pectoris": 4.271805844339797, "Anti-GAD antibody positive": 46.94203452299474, "Anti-insulin antibody": 104.9682555627916, "Anti-insulin antibody increased": 102.06150794099568, "Anti-insulin antibody positive": 86.2550002319259, "Apgar score low": 5.00185977069493, "Appendicitis": 2.8521232639984957, "Appendicolith": 5.620461383568686, "Appetite disorder": 22.987079868674535, "Areflexia": 6.105580091183346, "Arterial occlusive disease": 2.361419941845703, "Bacterial infection": 2.2706649557604845, "Bladder disorder": 2.551869422486978, "Blindness": 3.0205837069450068, "Blindness unilateral": 2.5049992541720925, "Blood glucose abnormal": 21.82052023336469, "Blood glucose decreased": 21.98942813457114, "Blood glucose fluctuation": 39.67818794273048, "Blood glucose increased": 17.327836415387093, "Blood immunoglobulin E increased": 3.915670379105677, "Blood insulin increased": 47.95494624043382, "Blood pH decreased": 4.482496793435725, "Blood phosphorus increased": 4.646976453913692, "Blood pressure systolic increased": 2.191628588623225, "Body mass index increased": 8.287999087894026, "Brachial plexopathy": 26.462402127464188, "Bronchitis chronic": 12.57457495940387, "Caesarean section": 3.2070804102115846, "Cardiac disorder": 2.198844182532408, "Cardiac murmur": 3.397474866619421, "Cataract": 3.933209615028216, "Cataract operation": 2.009528693896498, "Cerebral ischaemia": 2.0043209818923096, "Cerebral reperfusion injury": 329.14904177587374, "Cholecystectomy": 2.034083591724163, "Chorea": 5.567275089227602, "Cold sweat": 2.879720354142908, "Coronary artery occlusion": 2.372296589033998, "Coronary artery stenosis": 2.614520162414578, "Cutaneous amyloidosis": 166.3607393250529, "Cystitis interstitial": 35.49558046118092, "Dementia": 2.4934080517172545, "Dementia Alzheimer's type": 2.6357814888686493, "Depressed mood": 2.726280023653208, "Depressive symptom": 20.04003398472772, "Device breakage": 3.171672103478413, "Device defective": 5.843258098079498, "Device issue": 6.81013712914356, "Device operational issue": 15.361646133155457, "Device use issue": 6.404554118369118, "Diabetes mellitus inadequate control": 31.43320458273843, "Diabetic coma": 11.618656415187392, "Diabetic complication": 21.55803787907776, "Diabetic foot": 27.46926848560356, "Diabetic ketoacidosis": 11.00095644272016, "Diabetic metabolic decompensation": 51.30736418361257, "Diabetic nephropathy": 8.097540259379958, "Diabetic neuropathy": 11.156010529092235, "Diabetic retinopathy": 23.693364850748715, "Disorganised speech": 3.61949011579763, "Drug administered in wrong device": 77.05478915919373, "Drug hypersensitivity": 3.078112481899803, "Drug level below therapeutic": 4.427269224871608, "Dyspnoea exertional": 3.235672228807494, "Erosive duodenitis": 12.210207537630676, "Expired product administered": 2.054620886081299, "Exposure during pregnancy": 2.386726188497033, "Extra dose administered": 5.33085882368994, "Eye haemorrhage": 3.9064654944551984, "Fall": 2.0266279081924794, "Flank pain": 13.795186314444358, "Foetal exposure during pregnancy": 3.8606507572945454, "Foetal exposure timing unspecified": 17.03224301123976, "Foetal growth restriction": 4.789515988164296, "Gangrene": 6.016234019801332, "Gastrointestinal carcinoma": 3.927741541993596, "Generalised oedema": 2.006434879007469, "Gestational hypertension": 13.98205614390136, "Glycosylated haemoglobin abnormal": 8.598739531160085, "Glycosylated haemoglobin decreased": 17.145558602460984, "Glycosylated haemoglobin increased": 26.80602783002848, "Heart sounds": 508.8804626505858, "Hemiplegia": 2.5989298683238418, "Hepatomegaly": 2.376032115493568, "Hunger": 9.04338645212568, "Hyperglycaemia": 21.221858243937994, "Hyperinsulinaemia": 27.4826214419794, "Hyperinsulinaemic hypoglycaemia": 26.21869653362764, "Hypoglycaemia": 38.38230946323628, "Hypoglycaemia neonatal": 51.724212301366855, "Hypoglycaemia unawareness": 36.922423731495655, "Hypoglycaemic coma": 41.78245654915433, "Hypoglycaemic encephalopathy": 39.824326529782674, "Hypoglycaemic seizure": 20.13314877417417, "Hypoglycaemic unconsciousness": 30.208265493121797, "Impaired gastric emptying": 3.4940164994538687, "Incorrect dose administered": 7.254577910158863, "Incorrect dose administered by device": 3.614264156967711, "Incorrect product administration duration": 2.206445927033962, "Increased appetite": 3.616464935646354, "Induration": 2.056809051639327, "Injection site abscess": 4.344750862787473, "Injection site atrophy": 59.340039074140186, "Injection site bruising": 3.162224010419262, "Injection site discolouration": 2.849633107356301, "Injection site hypersensitivity": 2.5615583574148046, "Injection site induration": 3.461988477181094, "Injection site nodule": 6.899289898787941, "Injection site urticaria": 6.972054910917696, "Injury": 4.159903566986409, "Injury associated with device": 7.988120154026569, "Insulin C-peptide decreased": 47.0142460643323, "Insulin C-peptide increased": 88.02955137683921, "Insulin autoimmune syndrome": 56.499012627679946, "Insulin resistance": 46.7737359422946, "Intentional dose omission": 2.8671034074035173, "Intentional overdose": 2.440935657898821, "Jaundice neonatal": 5.943720447108028, "Ketoacidosis": 10.824043715660942, "Ketosis": 7.867831675773611, "Left ventricular hypertrophy": 2.77865123651755, "Leg amputation": 5.440592901840442, "Limb injury": 2.1854326573313747, "Lipoatrophy": 23.656446569276422, "Lipodystrophy acquired": 5.906322113574764, "Lipohypertrophy": 17.41877711376577, "Localised infection": 2.938370815796912, "Loss of consciousness": 2.561508990626248, "Lower respiratory tract infection": 3.3542535375129336, "Malnutrition": 2.140396218281479, "Maternal exposure before pregnancy": 3.5295077731290694, "Maternal exposure during pregnancy": 2.608150306379016, "Medication error": 2.3442896045608816, "Metabolic disorder": 5.6456847864414215, "Metabolic syndrome": 8.450617181705182, "Microalbuminuria": 8.419120590345138, "Multi-organ disorder": 10.69036126527132, "Nasal congestion": 4.404901624536008, "Onychoclasis": 3.876954683686501, "Osteomyelitis": 2.7150477794562, "Pancreatic disorder": 2.603516878505885, "Polydipsia": 7.44196568028754, "Polyuria": 2.832422826026742, "Post procedural complication": 2.3069467458300186, "Postprandial hypoglycaemia": 55.21317761805444, "Pre-eclampsia": 11.984442666216708, "Premature baby": 6.537352805092491, "Premature delivery": 5.360217621049917, "Product dose omission issue": 2.40403509303208, "Product monitoring error": 25.687872330307226, "Product selection error": 15.758196937019164, "Product storage error": 7.8026868243681, "Productive cough": 5.005788636307933, "Prolonged expiration": 289.61684802116247, "Pulmonary arterial hypertension": 2.66700584992565, "Pulmonary mass": 2.909853517320088, "Rales": 19.27915013532489, "Renal disorder": 2.030282845157361, "Respiration abnormal": 15.384672251217475, "Retinal detachment": 2.7961704635819347, "Retinopathy": 5.289886323224127, "Rhinorrhoea": 2.599670084640165, "Road traffic accident": 2.293436635232934, "Shock hypoglycaemic": 11.424592459688617, "Shoulder fracture": 2.4210588011526992, "Skin induration": 2.524493414796467, "Skin mass": 3.797239320992056, "Skin test positive": 9.39358039773172, "Sleep disorder due to a general medical condition": 6.920007003483999, "Starvation": 17.346301075210526, "Stress": 6.060129646316224, "Suspected suicide": 4.04837287146744, "Systemic inflammatory response syndrome": 3.1069565454960104, "Tearfulness": 2.4207840880843943, "Toe amputation": 5.352584193383767, "Treatment noncompliance": 4.471113214965504, "Type 1 diabetes mellitus": 3.421556984230567, "Type I hypersensitivity": 5.943672061890271, "Type III immune complex mediated reaction": 21.87533758378331, "Unresponsive to stimuli": 3.918342452178876, "Upper respiratory tract infection": 5.100155942944798, "Urine ketone body present": 8.97634961452124, "Vascular stent stenosis": 19.338211774720406, "Visual impairment": 2.746067133494888, "Weight decreased": 2.3731650129182484, "Weight increased": 3.588940515777488, "Weight loss poor": 4.222670821182494, "Wheezing": 2.131915349406498, "Wrong product administered": 13.544522208943585, "Wrong technique in product usage process": 4.566462624161714}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/583.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/583.json
index 5890d808f9f..d9ef0144155 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/583.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/583.json
@@ -1 +1 @@
-{"Agitation ": 4.851999173345048, "Clostridium difficile colitis ": 75.26220815004392, "Clostridium difficile infection ": 24.28068171944017, "Clostridium test positive ": 354.08815233641167, "Confusional state ": 8.610774818277607, "Delirium ": 16.920843032439628, "Drug interaction ": 2.097861440581754, "Drug reaction with eosinophilia and systemic symptoms ": 13.5146753479387, "Epilepsy ": 6.104987061503228, "Hallucination ": 19.473425428213435, "Neutropenia ": 2.096129273746712, "Rash maculo-papular ": 5.624801001344587, "Seizure ": 7.380376883964889, "Speech disorder ": 7.385535311030932, "Thrombocytopenia ": 2.6761412178833583}
\ No newline at end of file
+{"Agitation": 2.8593307225004563, "Blood glucose abnormal": 32.15073150275138, "Blood glucose decreased": 11.79215330665054, "Blood glucose fluctuation": 44.4145866971573, "Blood glucose increased": 24.24844516194957, "Dermatitis allergic": 8.394612998488647, "Diabetes mellitus inadequate control": 21.62515435482284, "Drug ineffective": 3.0906200696093737, "Hyperglycaemia": 18.465977341689065, "Hypersensitivity": 3.874387570730978, "Hypoglycaemia": 28.73829489155645, "Hypoglycaemic coma": 35.20144740261754, "Ketoacidosis": 14.836894349817989, "Loss of consciousness": 2.262988218722121, "Product complaint": 8.109223304435012, "Product quality issue": 8.006479920118634, "Product storage error": 22.20525235270007, "Pruritus": 2.4455935171740077, "Shock hypoglycaemic": 565.3150908164297, "Stevens-Johnson syndrome": 6.057229131990138, "Therapeutic response decreased": 6.439673970069999}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/584.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/584.json
index bd0fcf89b15..333a7c1c18c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/584.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/584.json
@@ -1 +1 @@
-{"Abnormal weight gain ": 36.4521364922043, "Adverse drug reaction ": 4.44714800354435, "Aggression ": 7.991755507224294, "Agitation ": 4.644737778963431, "Akathisia ": 12.6583957862369, "Amenorrhoea ": 7.892499593476063, "Blood creatine phosphokinase increased ": 4.477519818808439, "Blood prolactin increased ": 141.64254342732255, "Breast enlargement ": 50.34546184779829, "Completed suicide ": 2.699931216496802, "Delusion ": 15.1523578975482, "Depressed mood ": 2.52863582089115, "Drug interaction ": 3.5823003638213358, "Dyskinesia ": 17.41556131767222, "Dystonia ": 18.64753383363957, "Dysuria ": 10.765802833813297, "Electrocardiogram QT prolonged ": 4.219308430202351, "Emotional disorder ": 11.593336288808644, "Extrapyramidal disorder ": 30.399788263878825, "Galactorrhoea ": 68.16745256660197, "Genital neoplasm malignant female ": 903.5286584417336, "Gynaecomastia ": 92.28047410441224, "Hallucination, auditory ": 17.692620719746742, "Hyperprolactinaemia ": 132.46205883078724, "Hypersomnia ": 6.01207201922781, "Inappropriate schedule of product administration ": 2.195184496674329, "Insomnia ": 2.1794372703530467, "Intentional overdose ": 10.229395938062794, "Intentional product misuse ": 2.4435521690193496, "Musculoskeletal stiffness ": 2.40739109565096, "Neuroleptic malignant syndrome ": 21.885678113490577, "Obesity ": 38.05853944663191, "Oculogyric crisis ": 29.95337294481709, "Off label use ": 2.035226561542561, "Overdose ": 2.735138234345458, "Parkinsonism ": 21.79121037476481, "Pneumonia aspiration ": 6.268929403487217, "Product use in unapproved indication ": 2.688067854004403, "Psychotic disorder ": 8.494303453081656, "Restlessness ": 2.839941153735127, "Rhabdomyolysis ": 2.0660382432029314, "Salivary hypersecretion ": 18.883259056039243, "Schizophrenia ": 26.52068628790617, "Sedation ": 9.30208094922216, "Sedation complication ": 41.62991226636201, "Self-destructive behaviour ": 122.61966924730778, "Sluggishness ": 22.562687853543807, "Somnolence ": 2.9298820006767348, "Sopor ": 21.06219722126083, "Suicidal ideation ": 2.302649916692346, "Suicide attempt ": 7.447787336658952, "Tardive dyskinesia ": 54.95648117928224, "Therapeutic product effect decreased ": 2.461156267610725, "Treatment noncompliance ": 15.917303404009376, "Tremor ": 3.6036109735638258, "Urinary retention ": 2.343642392080649, "Weight increased ": 9.115944954372004}
\ No newline at end of file
+{"Acute myocardial infarction": 3.835703028270673, "Atelectasis": 13.599422902071366, "Blood creatinine increased": 2.3902030808793446, "Bradycardia": 2.885892052627379, "Cardiac arrest": 3.996731613952982, "Cardiac tamponade": 35.392869542997, "Cardiogenic shock": 27.601603830101084, "Cerebral haemorrhage": 13.394588598119425, "Coronary artery disease": 5.419246917653654, "Coronary artery occlusion": 13.338233526765263, "Coronary artery thrombosis": 179.42443305229153, "Death": 3.205497284453947, "Depressed level of consciousness": 2.8342548527553384, "Epistaxis": 3.374395580793081, "Gastrointestinal haemorrhage": 7.035055564647983, "Gingival bleeding": 9.913264867442908, "Haematemesis": 15.603142729759774, "Haematocrit decreased": 8.535036944170484, "Haematoma": 10.763089054217128, "Haematuria": 9.858123716136872, "Haemoglobin decreased": 9.765933657006384, "Haemoptysis": 14.394136447758727, "Haemorrhage": 21.033080146512084, "Haemorrhage intracranial": 99.62991781874044, "Haemorrhagic stroke": 13.3021975125005, "Hyperglycaemia": 2.135309826814493, "Hypotension": 5.410097036027809, "Injection site haemorrhage": 13.002030102046518, "Melaena": 4.657064834481277, "Meningitis viral": 96.46591368346768, "Mitral valve incompetence": 15.995202876832636, "Multiple organ dysfunction syndrome": 3.976621746033693, "Myocardial infarction": 6.57120765111645, "Oxygen saturation decreased": 2.8389157224242147, "Petechiae": 5.555594037234224, "Platelet count decreased": 8.6654893868613, "Pleural effusion": 2.7327490971667805, "Product complaint": 4.992649438773675, "Pulmonary alveolar haemorrhage": 36.71392107007821, "Pulmonary haemorrhage": 40.508386290727714, "Pulmonary oedema": 5.173032246695088, "Retroperitoneal haemorrhage": 163.9798936559638, "Shock": 6.224400534317862, "Thrombocytopenia": 21.055986850338417, "Thrombosis": 10.43120476899411, "Thrombosis in device": 57.21520619148361, "Unresponsive to stimuli": 7.232909472730528, "Vascular stent thrombosis": 27.102178320942453}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/585.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/585.json
index fd9ee2c8cec..6b2a2ea1466 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/585.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/585.json
@@ -1 +1 @@
-{"Dehydration ": 11.001925952899311, "Fall ": 3.424470923795649}
\ No newline at end of file
+{"Abortion spontaneous": 4.546432581542087, "Anaemia": 2.842822682133357, "Blindness": 3.709520722607151, "Blood cholesterol increased": 5.019847277198758, "Blood creatine phosphokinase increased": 3.475451418412697, "Blood magnesium increased": 196.05906906058885, "Drug interaction": 3.205641610300448, "Drug level increased": 6.767579741795777, "Drug reaction with eosinophilia and systemic symptoms": 7.953018479796488, "Drug resistance": 5.547178033788962, "Dysarthria": 3.421208629107179, "Exposure during pregnancy": 7.613149553509169, "Eye pain": 2.7160391488955344, "Foetal exposure during pregnancy": 10.041149469213378, "Gait disturbance": 3.418983611240487, "H1N1 influenza": 147.18136326792742, "Hepatic cirrhosis": 10.659739972018835, "Hypercholesterolaemia": 20.331408852927524, "Lipodystrophy acquired": 57.52824164423886, "Lung lobectomy": 392.0162968566276, "Maternal exposure during pregnancy": 4.846197871679369, "Mitochondrial DNA depletion": 4803.567854497512, "Mitochondrial myopathy acquired": 1634.87883964271, "Mitochondrial toxicity": 108.03239645820874, "Mobility decreased": 2.588487564792472, "Multiple organ dysfunction syndrome": 3.835737953232934, "Myocardial infarction": 2.15311431672718, "Nervous system disorder": 17.010059857792, "Neuropathy peripheral": 9.499631956066608, "Neurotoxicity": 19.471394046635037, "Pancreatitis acute": 3.90052859478247, "Pollakiuria": 12.124317213615468, "Rash maculo-papular": 6.353346421745764, "Rash pruritic": 3.1398908464701853, "Red blood cell count decreased": 6.131405407137554, "Renal failure": 2.137193343868846, "Renal tubular disorder": 36.19940474362985, "Sleep disorder": 2.466520317712088, "Toxic skin eruption": 8.470208755337556, "Vitamin B6 deficiency": 853.9363846056168}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/586.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/586.json
index af2b7040993..c22f3fba6dd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/586.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/586.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.929645119649085, "Alanine aminotransferase increased ": 3.948482937859788, "Anaemia ": 3.033202596108638, "Angina unstable ": 31.72654167313184, "Aspartate aminotransferase increased ": 3.5779151390378616, "Blood cholesterol increased ": 3.8154871284687326, "Blood creatine phosphokinase increased ": 3.2467921984801187, "Blood lactic acid increased ": 48.75450212338035, "Blood triglycerides increased ": 23.748769832251284, "Diabetes mellitus ": 13.702374618233254, "Diabetic ketoacidosis ": 4.30234548388804, "Drug interaction ": 3.834601339199678, "Dysgeusia ": 2.7742211693576886, "Gamma-glutamyltransferase increased ": 3.3824270447191336, "Hepatic cirrhosis ": 7.95494270063493, "Hepatic enzyme increased ": 2.0586104908299965, "Hepatic failure ": 8.932145023673755, "Hepatitis ": 10.170352798083334, "Hepatomegaly ": 20.812618482064707, "Hepatotoxicity ": 6.083870705208882, "Hypercholesterolaemia ": 29.71684111750704, "Hyperglycaemia ": 2.6513000513292195, "Hypertriglyceridaemia ": 119.9334095543476, "Hypokalaemia ": 3.1373967681054253, "Hypotonia ": 7.923019980290586, "Jaundice ": 4.303744149156755, "Lactic acidosis ": 13.189574486225942, "Lipodystrophy acquired ": 107.48170491901207, "Live birth ": 14.963944881939105, "Liver function test abnormal ": 5.967640076123396, "Mitochondrial cytopathy ": 188.1958555668036, "Myocardial infarction ": 3.1964369748732766, "Neuropathy peripheral ": 2.645611189398636, "Neutropenia ": 4.177826260180009, "Osteonecrosis ": 3.397353505165784, "Pancreatitis ": 6.803109053075297, "Pancreatitis acute ": 6.8706616635760085, "Premature baby ": 5.12318380530117, "Pulmonary hypertension ": 6.968597543299654, "Renal failure ": 2.257577482001422, "Rhabdomyolysis ": 3.908097216322319, "Sepsis ": 2.112004244115168, "Stevens-Johnson syndrome ": 5.18114460238931, "Thrombocytopenia ": 2.3111658922009344, "Transaminases increased ": 4.9240327138088205}
\ No newline at end of file
+{"Anaemia": 5.019918709679311, "Depression": 4.6108796678941, "Haemoglobin decreased": 3.020494907266305, "Haemolytic anaemia": 11.715555197298055, "Hepatic cirrhosis": 8.66354073960194, "Hepatic failure": 5.082185707007766, "Hyperthyroidism": 10.790047126681598, "Hypothyroidism": 9.94358682446966, "Lethargy": 3.350577336109295, "Neutropenia": 2.912068251543779, "Pancytopenia": 2.5271831823825943, "Platelet count decreased": 2.8186379042981486, "Rash pruritic": 2.303674630269364, "Sleep disorder": 2.004626325889361, "Therapy non-responder": 9.76263549467276, "Weight decreased": 3.0075023352844235, "White blood cell count decreased": 3.9589913980705234}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/587.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/587.json
index 696486a2805..62f837007a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/587.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/587.json
@@ -1 +1 @@
-{"Abnormal loss of weight ": 10.850415787038829, "Accidental exposure to product by child ": 16.224040042189866, "Acute kidney injury ": 40.850707409584885, "Acute respiratory failure ": 16.90788920558382, "Amputation ": 212.1455539523325, "Asthma-chronic obstructive pulmonary disease overlap syndrome ": 89.93854887139695, "Blood glucose decreased ": 4.678144224379471, "Bronchiectasis ": 9.1888848388842, "Cellulitis ": 16.604928654713408, "Dehydration ": 9.037702670351509, "Diabetes mellitus inadequate control ": 9.360549912086556, "Diabetic foot ": 349.4085678851333, "Diabetic foot infection ": 1113.6493314067463, "Diabetic ketoacidosis ": 245.70819420025737, "Dry gangrene ": 226.4341849909896, "Encephalopathy ": 6.227337894992647, "Euglycaemic diabetic ketoacidosis ": 51.56630694276225, "Foot amputation ": 567.3089878642406, "Fournier's gangrene ": 29.700321249119792, "Full blood count abnormal ": 6.299675955740804, "Fungal infection ": 5.835271486718919, "Gangrene ": 117.15922691018568, "Gas gangrene ": 273.96623485230424, "Gastroenteritis ": 5.524572912058302, "Gastrooesophageal reflux disease ": 3.2746162923476883, "Glycosylated haemoglobin increased ": 5.355835441293127, "Hyperglycaemia ": 4.322530604586033, "Hyperkalaemia ": 4.750934652391743, "Hypoglycaemia ": 2.6032883215117533, "Incorrect dose administered ": 5.309192184949658, "Ketoacidosis ": 49.04761660825751, "Kidney infection ": 6.30676188283176, "Lactic acidosis ": 4.822680612783729, "Leg amputation ": 213.12920258511377, "Leukocytosis ": 6.739419834490064, "Limb amputation ": 464.515703934641, "Localised infection ": 4.982933844170973, "Metabolic acidosis ": 35.09673005468178, "Metabolic encephalopathy ": 54.81103034817952, "Metatarsal excision ": 1190.3828331667223, "Multiple allergies ": 19.399175792702227, "Mycobacterial infection ": 42.24188768373045, "Myocardial infarction ": 2.8731209675729468, "Necrotising fasciitis ": 48.16911737572099, "Obesity ": 4.619202327250742, "Obstructive airways disorder ": 3.8711505949287215, "Osteomyelitis ": 148.59832760374488, "Osteomyelitis acute ": 466.94296709079504, "Pancreatitis ": 5.049986261556998, "Pancreatitis acute ": 6.816723529365103, "Pollakiuria ": 2.1351278355626984, "Pyelonephritis ": 20.150744044135763, "Renal abscess ": 85.79578053450582, "Renal failure ": 3.2654391480733995, "Renal injury ": 2.2548012230903014, "Renal tubular necrosis ": 6.47294286560612, "Respiratory failure ": 2.64167759161365, "Sepsis ": 9.41449086248998, "Septic shock ": 8.617050485520519, "Skin ulcer ": 12.8946572172465, "Systemic inflammatory response syndrome ": 30.685230243135727, "Toe amputation ": 504.1782489129577, "Treatment noncompliance ": 20.74200184961655, "Type 2 diabetes mellitus ": 10.16238964797084, "Urinary tract infection ": 8.990498459148343, "Urosepsis ": 53.23538028705553, "Vulvovaginal mycotic infection ": 25.288627745971905, "Weight decreased ": 2.949246785447349}
\ No newline at end of file
+{"Abortion induced": 12.54486533736513, "Affect lability": 10.212844626797075, "Aggression": 4.181127741410827, "Altered state of consciousness": 2.092654666118045, "Amnesia": 2.357081350582774, "Anaemia": 8.87785976906131, "Ascites": 5.518125061279705, "Blood lactate dehydrogenase increased": 2.900355183044035, "Blood thyroid stimulating hormone increased": 7.019218225295544, "Bronchitis": 2.483026217347055, "Central venous catheterisation": 23.25685931960968, "Cerebral haemorrhage": 4.178954828261928, "Cerebral infarction": 2.615170887647368, "Cognitive disorder": 2.153039032474172, "Colitis ischaemic": 16.695882635023157, "Deafness": 2.540927256395358, "Decreased appetite": 4.7655647339307725, "Dehydration": 2.224920053915086, "Dementia": 3.0672261014682647, "Depression": 7.497346323178047, "Depressive symptom": 15.879332119412894, "Diabetes mellitus": 7.882482432473407, "Disseminated intravascular coagulation": 3.195812437602445, "Facial paralysis": 2.0666796156607155, "Foetal death": 15.198744649563524, "Gingival bleeding": 3.262624305993968, "Granulocyte count decreased": 33.74502690751007, "Granulocytopenia": 6.98516733525301, "Haemoglobin decreased": 4.814137752741623, "Haemolytic anaemia": 18.447631254296628, "Helicobacter infection": 2.507787583909556, "Hepatic cirrhosis": 7.215738714312078, "Hepatic encephalopathy": 5.475564904564629, "Hepatic failure": 4.221086457258415, "Hyperthyroidism": 9.335243087282992, "Hypoacusis": 3.2731994039646195, "Hypoalbuminaemia": 7.149185188044743, "Hypothyroidism": 8.604319828204773, "Immune thrombocytopenia": 3.9606177576914714, "Insomnia": 2.6949970071165663, "Interstitial lung disease": 4.567996500738476, "Irritability": 3.725740395822753, "Jaundice": 3.0423533520306183, "Leukopenia": 5.252399347358484, "Mania": 6.337118613283159, "Mental disorder": 2.7581073436713144, "Nephrotic syndrome": 6.62360406406957, "Optic neuritis": 7.712711717318518, "Pancreatitis": 2.083909232317406, "Paranoia": 3.3343337518119984, "Platelet count decreased": 5.260212542852878, "Pleural effusion": 2.7364357279755067, "Psychotic disorder": 2.4154655399077165, "Retinal exudates": 31.436448157819083, "Retinal haemorrhage": 33.485233373825295, "Retinal vein occlusion": 15.613812942114516, "Retinopathy": 33.46814813320723, "Sarcoidosis": 10.236303744746046, "Subarachnoid haemorrhage": 4.523764780366626, "Suicidal ideation": 4.438242023091989, "Suicide attempt": 3.197394006889928, "Thrombocytopenia": 3.2383689838529546, "Thyroid disorder": 3.335622607398148, "Type 1 diabetes mellitus": 11.643094586855527, "Visual acuity reduced": 2.6690351352316832, "Visual field defect": 4.859648416242328, "Weight decreased": 2.4580696854777937, "White blood cell count decreased": 3.940577973735394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/588.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/588.json
index a4a6dcfe61c..2e7eb9c5b50 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/588.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/588.json
@@ -1 +1 @@
-{"Addison's disease ": 33.41518997901263, "Adrenal insufficiency ": 27.10040061042941, "Adrenalitis ": 221.59627095045536, "Adrenocortical insufficiency acute ": 14.090822527498725, "Adrenocorticotropic hormone deficiency ": 68.06164462891408, "Amylase increased ": 2.085031515863356, "Aplasia pure red cell ": 2.784467066528548, "Aplastic anaemia ": 2.486168795344502, "Arthritis ": 5.236890875852426, "Autoimmune arthritis ": 63.58495963716963, "Autoimmune colitis ": 325.5770944991305, "Autoimmune haemolytic anaemia ": 13.880022687975002, "Autoimmune hepatitis ": 51.54027169247216, "Autoimmune hypothyroidism ": 47.27680113505468, "Autoimmune nephritis ": 190.2043671983852, "Autoimmune pancreatitis ": 64.7715477480444, "Autoimmune thyroiditis ": 24.84058458649042, "Capillary leak syndrome ": 9.122397677917748, "Chronic gastritis ": 8.301569175555496, "Clostridium difficile infection ": 2.508613837488696, "Colitis ": 66.1042328423263, "Cortisol decreased ": 7.824902358335052, "Cutaneous vasculitis ": 5.026146201745092, "Cytokine release syndrome ": 2.778727039835094, "Dermatitis ": 5.698068196672309, "Diabetes mellitus ": 2.712612978953228, "Diabetic ketoacidosis ": 6.098810213645955, "Diarrhoea ": 2.1876275852311524, "Diarrhoea haemorrhagic ": 2.286442173828978, "Drug-induced liver injury ": 2.5067612910556094, "Duodenitis ": 20.940303671947945, "Encephalitis ": 10.559856827701788, "Encephalitis autoimmune ": 26.694867674898703, "Endocrine disorder ": 34.18757059239579, "Enteritis ": 12.609878247950771, "Enterocolitis ": 14.18662319144116, "Fulminant type 1 diabetes mellitus ": 51.11545576917631, "Gastritis ": 2.79945464102805, "Giant cell arteritis ": 9.109378620817504, "Glomerulonephritis ": 11.684935902526489, "Glucocorticoid deficiency ": 93.33687687709478, "Granuloma ": 6.016820916352349, "Guillain-Barre syndrome ": 7.194192879250318, "Haemophagocytic lymphohistiocytosis ": 11.841191342117146, "Hepatic cytolysis ": 2.302952221648148, "Hepatic lesion ": 4.6931242684799095, "Hepatitis ": 25.422253598697, "Hepatitis acute ": 2.208515980355958, "Hepatotoxicity ": 18.084465198137583, "Hyperthyroidism ": 14.384329526311053, "Hypertransaminasaemia ": 13.398479899659156, "Hypomagnesaemia ": 3.41010329683911, "Hypophysitis ": 486.2967077921366, "Hypopituitarism ": 88.60814365829427, "Hypothalamo-pituitary disorder ": 17.266786365829507, "Hypothyroidism ": 13.434881726666614, "Immune thrombocytopenia ": 6.658732495992841, "Immune-mediated adrenal insufficiency ": 39.4604514723791, "Immune-mediated adverse reaction ": 66.64906496063064, "Immune-mediated arthritis ": 78.92881584574202, "Immune-mediated dermatitis ": 98.94122353716833, "Immune-mediated encephalitis ": 284.9756724361475, "Immune-mediated enterocolitis ": 296.79190779537004, "Immune-mediated gastritis ": 154.62525109794524, "Immune-mediated hepatic disorder ": 32.07000010915875, "Immune-mediated hepatitis ": 388.0625496062652, "Immune-mediated hyperthyroidism ": 56.0123608654396, "Immune-mediated hypophysitis ": 856.2227396132345, "Immune-mediated hypothyroidism ": 44.30409769261316, "Immune-mediated lung disease ": 130.25320983857247, "Immune-mediated myasthenia gravis ": 105.08007748062978, "Immune-mediated myocarditis ": 229.4228018276204, "Immune-mediated myositis ": 106.29353756716668, "Immune-mediated nephritis ": 268.11830719659974, "Immune-mediated neuropathy ": 162.24804260204309, "Immune-mediated pancreatitis ": 89.0312362604972, "Immune-mediated thyroiditis ": 349.93941749374187, "Immune-mediated uveitis ": 237.77810539460356, "Intentional product use issue ": 19.045617853119158, "Intestinal perforation ": 8.507515880975806, "Iridocyclitis ": 29.247058088192155, "Kidney transplant rejection ": 7.308882660852478, "Large intestine perforation ": 14.1312095025065, "Lichenoid keratosis ": 13.016764537000531, "Lipase increased ": 4.333568386422847, "Lymphocytic hypophysitis ": 558.4777228864215, "Malignant melanoma ": 2.930529179041703, "Malignant neoplasm progression ": 27.755525810245462, "Melanoma recurrent ": 40.76271445567616, "Meningitis ": 3.548983673908793, "Meningitis aseptic ": 8.047001915998338, "Metastases to central nervous system ": 17.19086188377956, "Metastases to liver ": 2.2836365542458195, "Metastases to lung ": 6.438861607838036, "Metastases to lymph nodes ": 4.478887375105418, "Metastasis ": 4.070435754520704, "Metastatic malignant melanoma ": 21.94798157927847, "Myasthenia gravis ": 22.77116436963525, "Myasthenic syndrome ": 30.15867478453428, "Myocarditis ": 8.622128064118565, "Myopathy ": 4.157478503697465, "Myositis ": 23.00058399342101, "Nephritis ": 23.81096487403195, "Non-small cell lung cancer ": 14.374157110331277, "Off label use ": 2.4471945765108334, "Optic neuritis ": 6.291091398036157, "Orbital myositis ": 162.43734978402895, "Organising pneumonia ": 3.560433136185261, "Pancreatic enzymes increased ": 10.572297065075528, "Pemphigoid ": 7.308260249922632, "Peritonitis ": 2.2190722713139697, "Pneumocystis jirovecii pneumonia ": 2.082410976904716, "Pneumonitis ": 28.607869287609, "Polyarthritis ": 11.23661901865747, "Polymyalgia rheumatica ": 4.715348616344248, "Polymyositis ": 11.325017009955308, "Polyneuropathy ": 5.290614128625591, "Prescribed overdose ": 3.019148756330173, "Prescribed underdose ": 4.603506628675699, "Primary hypothyroidism ": 55.39933377858444, "Pulmonary mass ": 2.518144752577629, "Pulmonary toxicity ": 5.0893657882930885, "Radiation necrosis ": 112.07697226903947, "Radiculopathy ": 2.3856552349305784, "Rash maculo-papular ": 2.661380821192988, "Sarcoidosis ": 10.22796560870914, "Secondary adrenocortical insufficiency ": 57.4108844572086, "Sjogren's syndrome ": 11.430293049913464, "Skin toxicity ": 16.529410227504226, "Thyroid disorder ": 4.45171356922315, "Thyroiditis ": 70.05052279764486, "Thyrotoxic crisis ": 16.00775582564924, "Toxic epidermal necrolysis ": 3.686371464834559, "Transaminases increased ": 2.4478468231851984, "Transfusion ": 2.311058722106648, "Tubulointerstitial nephritis ": 11.279064762142358, "Tumour pseudoprogression ": 61.98276320803039, "Type 1 diabetes mellitus ": 39.60417912390341, "Uveitis ": 10.417910022718075, "Vasculitis ": 2.4205366342644146, "Vitiligo ": 112.66543173819584, "Vogt-Koyanagi-Harada disease ": 30.65577505972935}
\ No newline at end of file
+{"Adverse drug reaction": 46.95851037294072, "Anger": 65.12814380348618, "Brain lobectomy": 13984.089535116078, "Seizure": 6.858855197070453}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/589.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/589.json
index 3c06696c6c0..38df05e82cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/589.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/589.json
@@ -1 +1 @@
-{"Acidosis ": 3.19258373693702, "Acute kidney injury ": 11.958328500161532, "Adjustment disorder ": 11.864618588958349, "Affect lability ": 2.239939030146136, "Angioedema ": 5.969298027062175, "Anuria ": 6.395079655963421, "Aortic aneurysm ": 7.628220743712314, "Arteriosclerosis coronary artery ": 3.5859000766069, "Atrial fibrillation ": 2.92151138269778, "Atrioventricular block first degree ": 7.00850753482841, "Autoimmune hepatitis ": 4.1307925051756245, "Blood calcium abnormal ": 24.73191768451817, "Blood immunoglobulin E increased ": 14.168890113224784, "Blood potassium increased ": 6.435437934543185, "Blood pressure decreased ": 2.23204754147208, "Blood pressure inadequately controlled ": 10.563412562667695, "Blood pressure increased ": 2.8352459456034658, "Blood pressure systolic increased ": 5.592911012115222, "Blood sodium decreased ": 3.6257053742040894, "Blood thyroid stimulating hormone abnormal ": 45.9891528125131, "Body temperature decreased ": 4.212431284272316, "Bradycardia ": 3.619958624820904, "Brain natriuretic peptide abnormal ": 169.5080842160149, "Bundle branch block left ": 13.32397131700644, "Bundle branch block right ": 9.853010291316506, "Cardiac failure chronic ": 7.355031865143697, "Cardio-respiratory arrest ": 4.064952929141512, "Cardiogenic shock ": 5.037826818911573, "Cardiomegaly ": 4.026338499462886, "Cell death ": 22.00405209910552, "Choking ": 2.3272563654825715, "Cholestasis ": 3.539711827522515, "Concussion ": 5.549178584198931, "Conduction disorder ": 19.92712319398857, "Coordination abnormal ": 2.2069641789403747, "Dehydration ": 3.490297988187772, "Drug interaction ": 3.389479153505028, "Drug reaction with eosinophilia and systemic symptoms ": 2.2737388779374763, "Dysgeusia ": 2.042372789268117, "Dyslipidaemia ": 7.435931195961746, "Dysmetria ": 134.92989091020652, "Eczema ": 3.2869846394520734, "Ejection fraction decreased ": 3.929027789832991, "Electrocardiogram QRS complex abnormal ": 97.0310900613415, "Electrocardiogram QT prolonged ": 3.7484294569976098, "Electrolyte imbalance ": 3.688027549686892, "Eosinophilia ": 5.285994348254948, "Expanded disability status scale score increased ": 97.23315952462826, "Extra dose administered ": 3.3056372428490173, "Extrapyramidal disorder ": 2.114318540252831, "Extrasystoles ": 6.926790779835981, "Fall ": 3.863718671286468, "Fluid intake reduced ": 10.47750429717237, "Fractured coccyx ": 45.02893113078954, "Gait spastic ": 545.6683246105284, "Goitre ": 10.528454952190708, "Gout ": 2.188177064547534, "Haematuria ": 2.768685900823205, "Hemiparesis ": 2.7166888161911498, "Hemiplegia ": 3.2293644339674965, "Hepatic cytolysis ": 2.135199549619509, "Hepatic failure ": 2.7390226056209133, "Hiatus hernia ": 2.240430234191863, "Hypercalcaemia ": 3.228570718867339, "Hyperkalaemia ": 16.410012004643523, "Hypertension ": 2.0954956251313868, "Hyperuricaemia ": 5.005433905653601, "Hypokalaemia ": 3.857191535637191, "Hypokinesia ": 8.09776737822522, "Hypomagnesaemia ": 3.911402930919412, "Hyponatraemia ": 10.27569665805074, "Hypophagia ": 3.96570591413869, "Hypotension ": 6.636758919190945, "Hypovolaemia ": 4.608087195934704, "Inappropriate antidiuretic hormone secretion ": 3.073558305953341, "Insulinoma ": 188.33467845780336, "Lactic acidosis ": 8.469649436089473, "Left ventricular dilatation ": 32.987062152563816, "Leukocytosis ": 2.4007062342222567, "Lip swelling ": 2.3642070817755774, "Lymphoedema ": 4.704948622008581, "Lymphopenia ": 9.354812321814732, "Metabolic acidosis ": 3.1010784619048923, "Mitral valve incompetence ": 6.211170183147972, "Muscle spasticity ": 16.24827066279386, "Muscular weakness ": 2.541352237650241, "Musculoskeletal discomfort ": 9.953365071502423, "N-terminal prohormone brain natriuretic peptide abnormal ": 400.94499438346753, "Nodal rhythm ": 13.49443218263164, "Obstructive airways disorder ": 2.5180717189263224, "Obstructive sleep apnoea syndrome ": 34.4898290623038, "Oedema peripheral ": 2.9372207252676663, "Oliguria ": 3.6716842470271143, "Orthostatic hypotension ": 11.574113427824372, "Oxygen saturation increased ": 128.9482607467275, "Pemphigoid ": 5.745747651360943, "Photosensitivity reaction ": 2.862349617962733, "Poisoning ": 4.114685025399158, "Polydipsia ": 5.399581495360236, "Product substitution issue ": 15.6367401964026, "Pulmonary arterial pressure abnormal ": 167.3149328719622, "Pulmonary granuloma ": 33.05367305716744, "Rales ": 4.144111679596472, "Renal impairment ": 3.02852599958778, "Renal tubular necrosis ": 8.814977681348017, "Rhabdomyolysis ": 3.0272445906373364, "Shock ": 2.259259824064036, "Sinus arrest ": 9.985936513252224, "Sinus bradycardia ": 9.246055247944906, "Sinus node dysfunction ": 7.119084460301326, "Sleep apnoea syndrome ": 2.563521737044622, "Supraventricular extrasystoles ": 20.880086495906045, "Swollen tongue ": 3.1750382884388038, "Tachypnoea ": 3.276830169181945, "Therapeutic response unexpected ": 4.408580087441388, "Thyroiditis ": 5.78630768753406, "Torsade de pointes ": 11.290885564312942, "Tricuspid valve incompetence ": 10.79322902873088, "Troponin increased ": 5.932421160486333, "Tubulointerstitial nephritis ": 2.857486746749439, "Urinary incontinence ": 6.378393739002189, "Urine abnormality ": 47.405342593667335, "Urine output decreased ": 6.310746909011693, "Ventricular fibrillation ": 5.353085921616906, "Ventricular hypokinesia ": 9.683128779864218, "Wrong patient received product ": 25.572174983357847, "Wrong product administered ": 2.127178100957832, "Xerosis ": 27.237514801319797}
\ No newline at end of file
+{"Agitation": 4.851999173345048, "Clostridium difficile colitis": 75.26220815004392, "Clostridium difficile infection": 24.28068171944017, "Clostridium test positive": 354.08815233641167, "Confusional state": 8.610774818277607, "Delirium": 16.920843032439628, "Drug interaction": 2.097861440581754, "Drug reaction with eosinophilia and systemic symptoms": 13.513559208705493, "Epilepsy": 6.104987061503228, "Hallucination": 19.473425428213435, "Neutropenia": 2.0960391464214547, "Rash maculo-papular": 5.624801001344587, "Seizure": 7.379558598236514, "Speech disorder": 7.385535311030932, "Thrombocytopenia": 2.675889490260088}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/59.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/59.json
index 2819937b50e..4fe68fe34dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/59.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/59.json
@@ -1 +1 @@
-{"Blood creatinine increased ": 2.401949180903367, "Blood glucose abnormal ": 9.06533303656946, "Blood glucose increased ": 5.336804459230629, "Bone lesion ": 144.37396459988793, "Breast cancer ": 18.173663496496665, "Breast cancer metastatic ": 78.26872288510475, "Colitis ": 12.057460787261917, "Decreased appetite ": 3.3957480849402053, "Diabetes mellitus ": 6.287278265310076, "Diabetic ketoacidosis ": 13.721487383478536, "Diarrhoea ": 3.3534145963512763, "Disease progression ": 3.180679690230368, "Glomerular filtration rate decreased ": 8.32963304444604, "Hepatic lesion ": 36.89639442563308, "Hyperglycaemia ": 66.83909950677229, "Ketoacidosis ": 12.542344745093494, "Malignant neoplasm progression ": 22.57815466307848, "Metastases to bone ": 86.4907984598958, "Metastases to central nervous system ": 24.052704377612688, "Metastases to liver ": 54.324832692377214, "Metastases to lung ": 23.682241113965883, "Mucosal inflammation ": 7.85130941763764, "Non-small cell lung cancer metastatic ": 332.6209519828068, "Rash ": 4.627759400842615, "Rash maculo-papular ": 4.030981195593474, "Therapy partial responder ": 19.354323675007983, "Weight decreased ": 3.1720607052156304}
\ No newline at end of file
+{"Alanine aminotransferase increased": 5.256692338989005, "Alopecia": 3.578587789463588, "Altered state of consciousness": 6.640526091070373, "Aspartate aminotransferase increased": 6.008725020825621, "Blood alkaline phosphatase increased": 11.42816061559514, "Blood bilirubin increased": 9.843290135730951, "Cholestasis": 19.729984872759196, "Constipation": 2.518250336260491, "Depressed level of consciousness": 5.137880036911207, "Drug-induced liver injury": 9.206131593335076, "Electrocardiogram QT prolonged": 8.226379892404765, "Febrile neutropenia": 7.775614210119801, "Haemolysis": 91.04718887035745, "Hepatic enzyme increased": 8.90267033169458, "Hypersensitivity": 2.270165281457616, "Hypokalaemia": 4.068647694150727, "Hyponatraemia": 3.203744470085851, "Hypophagia": 23.469966448367465, "Interstitial lung disease": 6.442653242552805, "Jaundice": 15.536059121445389, "Muscle spasms": 2.592170907969974, "Neutropenia": 2.1648226549101324, "Palmar-plantar erythrodysaesthesia syndrome": 13.355275236298018, "Wheezing": 4.279935910714646}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/590.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/590.json
index 1265baa9e60..cc060649cad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/590.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/590.json
@@ -1 +1 @@
-{"Acne ": 8.154198755526084, "Acquired gene mutation ": 69.7042989401872, "Acute respiratory distress syndrome ": 3.937171148402339, "Acute respiratory failure ": 6.8508167402690034, "Alanine aminotransferase increased ": 2.495375072118109, "Aspartate aminotransferase increased ": 2.36692328552314, "Atelectasis ": 2.4266284598894226, "Brain neoplasm ": 4.505140404453085, "Brain oedema ": 2.976459914054294, "Carcinoembryonic antigen increased ": 27.00912365139867, "Cerebral disorder ": 3.181319889664957, "Cerebral infarction ": 4.390647290760168, "Chest X-ray abnormal ": 4.587924595632598, "Cutaneous symptom ": 34.78099360469639, "Cystitis haemorrhagic ": 24.063605984710385, "Death ": 2.036537509337825, "Decreased appetite ": 2.722525946076958, "Dermatitis ": 6.059886490125115, "Dermatitis acneiform ": 54.42788815540443, "Diarrhoea ": 3.43195063160173, "Disease progression ": 7.2164889283722, "Disseminated intravascular coagulation ": 5.397030623116333, "Drug eruption ": 2.6541288295745358, "Drug resistance ": 70.67642715786374, "Drug tolerance ": 16.780137723758106, "Drug-induced liver injury ": 3.3954784381514456, "Dry skin ": 8.01838755447787, "EGFR gene mutation ": 107.23376182237224, "Eczema ": 2.935566774734069, "Enterocolitis ": 5.2064274348912765, "Gastric ulcer ": 2.239559524781864, "Gastrointestinal perforation ": 5.0569163625333, "Gene mutation ": 30.909304431817933, "Glossitis ": 7.513602512433928, "Haematuria ": 2.656481204132464, "Haemoptysis ": 4.967856209861063, "Hepatic cytolysis ": 2.3240790738734174, "Hepatic function abnormal ": 17.140323775773716, "Hepatotoxicity ": 2.3314064927057734, "Hydrothorax ": 39.81332002725986, "Hypertransaminasaemia ": 6.531480852162676, "Ileus ": 4.679579289264152, "Ingrowing nail ": 21.533846927067938, "Interstitial lung disease ": 76.98093674836446, "Intestinal obstruction ": 2.2174715403769296, "Leukoencephalopathy ": 9.047228067410376, "Liver disorder ": 12.835000063960898, "Liver function test abnormal ": 2.463257788588159, "Liver function test increased ": 2.6305809497949, "Lung carcinoma cell type unspecified recurrent ": 39.052140692189056, "Lung disorder ": 26.01572389184868, "Lung infiltration ": 2.9293397521386213, "Lung neoplasm malignant ": 3.717607999085944, "Lymphangiosis carcinomatosa ": 70.33819700889768, "Malignant neoplasm progression ": 24.02795548612873, "Malignant pleural effusion ": 29.596189572494023, "Metastases to bone ": 24.143152079819867, "Metastases to central nervous system ": 80.0331746628135, "Metastases to liver ": 6.638260761547869, "Metastases to lung ": 8.774142922998356, "Metastases to lymph nodes ": 13.49867076149224, "Metastases to meninges ": 79.9672614942064, "Metastases to pleura ": 33.3072167061144, "Metastases to spine ": 11.360625521153604, "Metastasis ": 31.50917039552248, "Mouth ulceration ": 2.9457374622225267, "Nail disorder ": 11.708200467416654, "Neoplasm progression ": 2.999499742324912, "Non-small cell lung cancer ": 4.371656697444121, "Non-small cell lung cancer recurrent ": 145.3852755723312, "Onychoclasis ": 7.312797983547702, "Paronychia ": 110.48531786560513, "Pericardial effusion ": 3.785930921858004, "Peritonitis ": 4.753691269167062, "Pleural effusion ": 8.540891072572432, "Pneumatosis intestinalis ": 22.450609301793232, "Pneumonia ": 2.139428720723449, "Pneumonia aspiration ": 2.309092362423352, "Pneumonia bacterial ": 10.327780174809508, "Pneumonitis ": 6.517559829522712, "Pneumothorax ": 7.775588441863413, "Pulmonary alveolar haemorrhage ": 5.783167906744686, "Pulmonary fibrosis ": 2.571176689742857, "Pulmonary mass ": 3.188748393657633, "Pulmonary toxicity ": 6.662793842786507, "Purpura ": 2.414375016645368, "Radiation pneumonitis ": 56.526177196016455, "Rash ": 3.925221401179489, "Rash pustular ": 6.458981539309405, "Respiratory failure ": 4.93282826126734, "Seborrhoeic dermatitis ": 13.181554866463816, "Skin disorder ": 6.348554775618841, "Skin exfoliation ": 3.332686353391652, "Skin fissures ": 8.94937851549259, "Skin toxicity ": 11.163595063292286, "Skin ulcer ": 3.319389773588747, "Small cell lung cancer ": 17.97279345992964, "Stomatitis ": 6.556163017751702, "Therapy cessation ": 4.548772475714912, "Transaminases increased ": 4.746103677619503, "Tumour marker increased ": 11.504208316702814}
\ No newline at end of file
+{"Abnormal weight gain": 36.4521364922043, "Adverse drug reaction": 4.44714800354435, "Aggression": 7.991755507224294, "Agitation": 4.644737778963431, "Akathisia": 12.6583957862369, "Amenorrhoea": 7.892499593476063, "Blood creatine phosphokinase increased": 4.477519818808439, "Blood prolactin increased": 141.64254342732255, "Breast enlargement": 50.34546184779829, "Completed suicide": 2.699931216496802, "Delusion": 15.1523578975482, "Depressed mood": 2.52863582089115, "Drug interaction": 3.5823003638213358, "Dyskinesia": 17.41556131767222, "Dystonia": 18.64753383363957, "Dysuria": 10.765802833813297, "Electrocardiogram QT prolonged": 4.219308430202351, "Emotional disorder": 11.593336288808644, "Extrapyramidal disorder": 30.399788263878825, "Galactorrhoea": 68.16745256660197, "Genital neoplasm malignant female": 903.5286584417336, "Gynaecomastia": 92.28047410441224, "Hallucination, auditory": 17.692620719746742, "Hyperprolactinaemia": 132.46205883078724, "Hypersomnia": 6.01207201922781, "Inappropriate schedule of product administration": 2.195184496674329, "Insomnia": 2.1794372703530467, "Intentional overdose": 10.229395938062794, "Intentional product misuse": 2.4435521690193496, "Musculoskeletal stiffness": 2.40739109565096, "Neuroleptic malignant syndrome": 21.885678113490577, "Obesity": 38.05853944663191, "Oculogyric crisis": 29.93228050128501, "Off label use": 2.0351463878859444, "Overdose": 2.735138234345458, "Parkinsonism": 21.79121037476481, "Pneumonia aspiration": 6.268929403487217, "Product use in unapproved indication": 2.687984012338703, "Psychotic disorder": 8.494303453081656, "Restlessness": 2.83979137097494, "Rhabdomyolysis": 2.0660382432029314, "Salivary hypersecretion": 18.874056521886285, "Schizophrenia": 26.52068628790617, "Sedation": 9.30208094922216, "Sedation complication": 41.62991226636201, "Self-destructive behaviour": 122.61966924730778, "Sluggishness": 22.562687853543807, "Somnolence": 2.9298496961176173, "Sopor": 21.06219722126083, "Suicidal ideation": 2.302649916692346, "Suicide attempt": 7.447787336658952, "Tardive dyskinesia": 54.95648117928224, "Therapeutic product effect decreased": 2.461156267610725, "Treatment noncompliance": 15.917303404009376, "Tremor": 3.6034748098430622, "Urinary retention": 2.343642392080649, "Weight increased": 9.115944954372004}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/591.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/591.json
index ca4ed5ee5d1..b5f4d67197b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/591.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/591.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 7.02028029248467, "Adenocarcinoma of colon ": 17.633609204137816, "Alveolar rhabdomyosarcoma ": 809.095363387587, "Anaemia ": 4.21724541568401, "Ascites ": 2.861341402460185, "Bacteraemia ": 3.018778767065414, "Bone marrow failure ": 4.144558632726223, "Carcinoembryonic antigen increased ": 16.19176160584576, "Cholangitis ": 10.23539343616353, "Cholinergic syndrome ": 45.54563049917256, "Chronic myeloid leukaemia ": 8.468102811618309, "Clostridium difficile colitis ": 2.4549686799063744, "Clostridium difficile infection ": 2.914459738912785, "Colitis ": 3.789579376070665, "Colon cancer ": 2.704008684058976, "Colon cancer metastatic ": 33.925576121019446, "Colorectal cancer metastatic ": 84.34960623697118, "Conjunctivitis ": 2.4261047855747604, "Constipation ": 2.499488283847584, "Cytopenia ": 2.5352545830792703, "Decreased appetite ": 2.9431996599606234, "Dehydration ": 2.4579145116107908, "Dermatitis acneiform ": 29.70039445224959, "Diarrhoea ": 5.097742531287526, "Disease progression ": 10.474127506045225, "Dry skin ": 3.868846136362426, "Dysarthria ": 7.504346796065818, "Ejection fraction decreased ": 3.60207960532419, "Enteritis ": 9.125975784089093, "Febrile neutropenia ": 14.53730251034466, "Gastrointestinal anastomotic leak ": 173.61877673092252, "Gastrointestinal toxicity ": 38.52815494834213, "Gene mutation ": 18.496858498157557, "General physical health deterioration ": 2.2018751558980947, "Haematotoxicity ": 32.65306852212763, "Hepatic encephalopathy ": 2.5169210702850555, "Hiccups ": 5.818771108992019, "Hyperammonaemia ": 7.329392227312188, "Hyperammonaemic encephalopathy ": 12.274097157135747, "Hypertransaminasaemia ": 10.544836731464718, "Hypokalaemia ": 2.2057721660785337, "Hypomagnesaemia ": 13.327159290455429, "Hypophagia ": 2.191803076310809, "Interstitial lung disease ": 2.6600711935397268, "Intestinal obstruction ": 2.8129105644195618, "Laryngospasm ": 4.690793080988447, "Leukoencephalopathy ": 7.30531746594093, "Leukopenia ": 5.283762298689871, "Lymphopenia ": 2.2216070985987826, "Malignant neoplasm progression ": 5.222260454482672, "Metastases to bone ": 5.865332170718887, "Metastases to central nervous system ": 5.109625320999466, "Metastases to liver ": 15.964499057576887, "Metastases to lung ": 12.575021989705675, "Metastases to lymph nodes ": 8.794897011381536, "Metastases to meninges ": 23.15263988029885, "Metastases to peritoneum ": 23.422164326674043, "Mucosal inflammation ": 16.573972843345164, "Myelodysplastic syndrome ": 4.005118359848836, "Myelosuppression ": 8.368814537554545, "Neoplasm progression ": 2.9764128957703253, "Neuropathy peripheral ": 10.579335729935806, "Neurotoxicity ": 16.67839111290034, "Neutropenia ": 19.427079053478412, "Neutropenic colitis ": 18.142800601224515, "Neutropenic sepsis ": 7.595501674003464, "Neutrophil count decreased ": 7.718934545372097, "Pancreatic carcinoma ": 2.11987767332525, "Pancreatic carcinoma metastatic ": 17.032738931035393, "Pancreatic carcinoma recurrent ": 178.4899887026813, "Pancytopenia ": 2.556826257080924, "Paronychia ": 25.965644440670207, "Peripheral sensory neuropathy ": 24.741762827475803, "Peritonitis ": 3.411495994258846, "Polyneuropathy ": 4.645608137473361, "Portal hypertension ": 9.869382948144722, "Proteinuria ": 3.586411327871009, "Prothrombin time prolonged ": 3.5924468892495334, "Pulmonary mass ": 3.750846947698205, "Rash pustular ": 4.364527910255722, "Skin toxicity ": 32.088302184901224, "Small intestinal obstruction ": 8.47455593627557, "Stomatitis ": 7.914997377245134, "Temperature intolerance ": 4.284914392819486, "Therapeutic response decreased ": 2.702430180870288, "Therapy partial responder ": 13.26666594775564, "Thrombocytopenia ": 8.12578521797749, "Transaminases increased ": 2.120744121235689, "Vomiting ": 2.80682183458651, "White blood cell count decreased ": 3.281021485433438}
\ No newline at end of file
+{"Dehydration": 11.001338724969422, "Fall": 3.424383149628719}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/592.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/592.json
index 12fb2eeb5ba..1bcbb8cfc16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/592.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/592.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 5.932005371640996, "Adverse event ": 5.139577155599635, "Adverse reaction ": 6.509293080257265, "Amnesia ": 2.7808194490059823, "Ankle fracture ": 6.864011722776922, "Antipsychotic drug level increased ": 41.64382396910717, "Arthritis infective ": 22.68599663096103, "Asthma ": 2.347636066606361, "Atrial fibrillation ": 2.0970978593117104, "Atrioventricular block first degree ": 25.392009194216357, "Blood iron decreased ": 15.697507529992688, "Brain fog ": 2.810825917073342, "Calciphylaxis ": 100.04045850853596, "Cardiac arrest ": 2.310532817045637, "Cardiac failure ": 2.221151480048332, "Chronic obstructive pulmonary disease ": 4.870584049920035, "Chronic spontaneous urticaria ": 54.45556841108845, "Clonus ": 18.02175576017883, "Coagulopathy ": 3.50709353019294, "Completed suicide ": 4.686805178073629, "Constipation ": 2.291443639283417, "Dementia Alzheimer's type ": 17.855250149778783, "Drug hypersensitivity ": 2.025163195910404, "Drug interaction ": 2.3218655313274223, "Electrocardiogram QT prolonged ": 3.152296753828457, "Exposure during pregnancy ": 3.869617154680877, "Fall ": 2.4801390998528263, "Foetal exposure during pregnancy ": 12.73538277520314, "Full blood count abnormal ": 2.4058601826710504, "Gastrooesophageal reflux disease ": 3.415932269904946, "Generalised oedema ": 4.682283903525589, "Haemoglobin decreased ": 2.18204567252758, "Head discomfort ": 5.230813008292253, "Heart rate decreased ": 3.366443240168534, "Hip surgery ": 28.855271783546023, "Hyperkalaemia ": 2.151128143043236, "Hypersomnia ": 4.946103305847822, "Hyperventilation ": 6.937358267364627, "Hypotension ": 2.093123428801628, "Implant site erosion ": 225.136020516175, "Implant site infection ": 83.09099201631, "Live birth ": 8.036657697663637, "Low birth weight baby ": 10.99021050548419, "Lower limb fracture ": 8.785541230540646, "Lower respiratory tract infection ": 2.4377833344801867, "Maternal exposure during pregnancy ": 4.415670321833552, "Meningitis ": 8.871124926098295, "Micturition disorder ": 20.092337341910685, "Muscle spasticity ": 10.26859269384046, "Obesity ": 4.898398896577418, "Pallor ": 2.503343024660426, "Premature baby ": 17.826570928774572, "Premature delivery ": 6.708356834204396, "Pulmonary hypertension ": 3.7427021417020616, "Purulent discharge ": 32.796400513698785, "Rash macular ": 2.133703944706537, "Respiratory distress ": 5.141985610462714, "Restlessness ": 2.4686466235699998, "Rib fracture ": 4.449471708752141, "Sinus disorder ": 13.942227610206992, "Sinusitis fungal ": 126.46166740720912, "Skin discolouration ": 3.336688381697896, "Sleep disorder due to a general medical condition ": 7.178404982553513, "Sputum discoloured ": 17.550379024374468, "Talipes ": 16.78504778320923, "Toxicity to various agents ": 4.852392448295709, "Umbilical cord around neck ": 116.6929442473178, "Vaginal infection ": 24.78797810159916, "Viral infection ": 3.604552430147829, "Wheezing ": 3.3635869350630774, "Wound dehiscence ": 40.43915961189301}
\ No newline at end of file
+{"Acute kidney injury": 2.929645119649085, "Alanine aminotransferase increased": 3.948482937859788, "Anaemia": 3.033202596108638, "Angina unstable": 31.72654167313184, "Aspartate aminotransferase increased": 3.5779151390378616, "Blood cholesterol increased": 3.8154871284687326, "Blood creatine phosphokinase increased": 3.2467921984801187, "Blood lactic acid increased": 48.75450212338035, "Blood triglycerides increased": 23.748769832251284, "Diabetes mellitus": 13.702374618233254, "Diabetic ketoacidosis": 4.30234548388804, "Drug interaction": 3.834601339199678, "Dysgeusia": 2.7742211693576886, "Gamma-glutamyltransferase increased": 3.3824270447191336, "Hepatic cirrhosis": 7.95494270063493, "Hepatic enzyme increased": 2.0586104908299965, "Hepatic failure": 8.932145023673755, "Hepatitis": 10.170352798083334, "Hepatomegaly": 20.812618482064707, "Hepatotoxicity": 6.083870705208882, "Hypercholesterolaemia": 29.71684111750704, "Hyperglycaemia": 2.6513000513292195, "Hypertriglyceridaemia": 119.9334095543476, "Hypokalaemia": 3.1373967681054253, "Hypotonia": 7.922168379135289, "Jaundice": 4.303744149156755, "Lactic acidosis": 13.189574486225942, "Lipodystrophy acquired": 107.48170491901207, "Live birth": 14.963944881939105, "Liver function test abnormal": 5.967640076123396, "Mitochondrial cytopathy": 188.1958555668036, "Myocardial infarction": 3.1964369748732766, "Neuropathy peripheral": 2.6455308707257155, "Neutropenia": 4.1776465495326445, "Osteonecrosis": 3.397353505165784, "Pancreatitis": 6.803109053075297, "Pancreatitis acute": 6.8706616635760085, "Premature baby": 5.12318380530117, "Pulmonary hypertension": 6.968597543299654, "Renal failure": 2.257577482001422, "Rhabdomyolysis": 3.908097216322319, "Sepsis": 2.112004244115168, "Stevens-Johnson syndrome": 5.18114460238931, "Thrombocytopenia": 2.3109484590252967, "Transaminases increased": 4.923731121867736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/593.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/593.json
index 5ce43c782d8..03667e56854 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/593.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/593.json
@@ -1 +1 @@
-{"Plasma cell myeloma ": 120.19680629071564}
\ No newline at end of file
+{"Abnormal loss of weight": 10.850415787038829, "Accidental exposure to product by child": 16.224040042189866, "Acute kidney injury": 40.850707409584885, "Acute respiratory failure": 16.90788920558382, "Amputation": 212.1455539523325, "Asthma-chronic obstructive pulmonary disease overlap syndrome": 89.93854887139695, "Blood glucose decreased": 4.678144224379471, "Bronchiectasis": 9.1888848388842, "Cellulitis": 16.604928654713408, "Dehydration": 9.037219215830897, "Diabetes mellitus inadequate control": 9.360549912086556, "Diabetic foot": 349.4085678851333, "Diabetic foot infection": 1113.6493314067463, "Diabetic ketoacidosis": 245.70819420025737, "Dry gangrene": 226.4341849909896, "Encephalopathy": 6.227337894992647, "Euglycaemic diabetic ketoacidosis": 51.56630694276225, "Foot amputation": 567.3089878642406, "Fournier's gangrene": 29.700321249119792, "Full blood count abnormal": 6.299675955740804, "Fungal infection": 5.833651037895012, "Gangrene": 117.15922691018568, "Gas gangrene": 273.96623485230424, "Gastroenteritis": 5.524572912058302, "Gastrooesophageal reflux disease": 3.2746162923476883, "Glycosylated haemoglobin increased": 5.355835441293127, "Hyperglycaemia": 4.322530604586033, "Hyperkalaemia": 4.750279016260229, "Hypoglycaemia": 2.603200402320889, "Incorrect dose administered": 5.309192184949658, "Ketoacidosis": 49.04761660825751, "Kidney infection": 6.30676188283176, "Lactic acidosis": 4.822680612783729, "Leg amputation": 213.12920258511377, "Leukocytosis": 6.739419834490064, "Limb amputation": 464.515703934641, "Localised infection": 4.982933844170973, "Metabolic acidosis": 35.09673005468178, "Metabolic encephalopathy": 54.81103034817952, "Metatarsal excision": 1190.3828331667223, "Multiple allergies": 19.399175792702227, "Mycobacterial infection": 42.24188768373045, "Myocardial infarction": 2.8731209675729468, "Necrotising fasciitis": 48.16911737572099, "Obesity": 4.619202327250742, "Obstructive airways disorder": 3.8711505949287215, "Osteomyelitis": 148.59832760374488, "Osteomyelitis acute": 466.94296709079504, "Pancreatitis": 5.049986261556998, "Pancreatitis acute": 6.816723529365103, "Pollakiuria": 2.1351278355626984, "Pyelonephritis": 20.150744044135763, "Renal abscess": 85.79578053450582, "Renal failure": 3.2654391480733995, "Renal injury": 2.2548012230903014, "Renal tubular necrosis": 6.47294286560612, "Respiratory failure": 2.641459395655162, "Sepsis": 9.41449086248998, "Septic shock": 8.617050485520519, "Skin ulcer": 12.8946572172465, "Systemic inflammatory response syndrome": 30.685230243135727, "Toe amputation": 504.1782489129577, "Treatment noncompliance": 20.74200184961655, "Type 2 diabetes mellitus": 10.16238964797084, "Urinary tract infection": 8.990498459148343, "Urosepsis": 53.23538028705553, "Vulvovaginal mycotic infection": 25.288627745971905, "Weight decreased": 2.949246785447349}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/594.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/594.json
index f5a289cc579..6dc5959c5bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/594.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/594.json
@@ -1 +1 @@
-{"Anaemia ": 4.531429335375327, "C-reactive protein increased ": 3.014901573046446, "Cerebral haemorrhage ": 8.576455355686022, "Drug interaction ": 2.894287993349752, "Epistaxis ": 3.814543015058492, "Eye haemorrhage ": 10.8854025500992, "Gastric haemorrhage ": 21.5939574161558, "Gastric ulcer haemorrhage ": 115.956823658567, "Gastritis haemorrhagic ": 228.4518689559682, "Gastrointestinal haemorrhage ": 39.32767285319074, "Haematemesis ": 20.048102492198485, "Haematoma ": 12.559726952073577, "Haematuria ": 4.93785051987726, "Haemoglobin decreased ": 3.82535811680806, "Haemoptysis ": 6.329459482389591, "Haemorrhage ": 7.595728311471835, "Haemorrhage intracranial ": 9.673882097408493, "Hepatic enzyme increased ": 3.237199686355869, "Leukopenia ": 3.604698234888086, "Melaena ": 28.611045219608908, "Pallor ": 4.493169715650098, "Pancytopenia ": 4.426080489926366, "Thrombocytopenia ": 6.909080914656066}
\ No newline at end of file
+{"Addison's disease": 33.41518997901263, "Adrenal insufficiency": 27.10040061042941, "Adrenalitis": 221.59627095045536, "Adrenocortical insufficiency acute": 14.090822527498725, "Adrenocorticotropic hormone deficiency": 68.06164462891408, "Amylase increased": 2.085031515863356, "Aplasia pure red cell": 2.784467066528548, "Aplastic anaemia": 2.486168795344502, "Arthritis": 5.236890875852426, "Autoimmune arthritis": 63.58495963716963, "Autoimmune colitis": 325.5770944991305, "Autoimmune haemolytic anaemia": 13.880022687975002, "Autoimmune hepatitis": 51.54027169247216, "Autoimmune hypothyroidism": 47.27680113505468, "Autoimmune nephritis": 190.2043671983852, "Autoimmune pancreatitis": 64.7715477480444, "Autoimmune thyroiditis": 24.84058458649042, "Capillary leak syndrome": 9.122397677917748, "Chronic gastritis": 8.301569175555496, "Clostridium difficile infection": 2.508613837488696, "Colitis": 66.1042328423263, "Cortisol decreased": 7.824902358335052, "Cutaneous vasculitis": 5.026146201745092, "Cytokine release syndrome": 2.778727039835094, "Dermatitis": 5.697319772514724, "Diabetes mellitus": 2.712612978953228, "Diabetic ketoacidosis": 6.098810213645955, "Diarrhoea": 2.187609299792367, "Diarrhoea haemorrhagic": 2.286442173828978, "Drug-induced liver injury": 2.506608265051396, "Duodenitis": 20.940303671947945, "Encephalitis": 10.559856827701788, "Encephalitis autoimmune": 26.694867674898703, "Endocrine disorder": 34.18757059239579, "Enteritis": 12.609878247950771, "Enterocolitis": 14.18662319144116, "Fulminant type 1 diabetes mellitus": 51.11545576917631, "Gastritis": 2.79945464102805, "Giant cell arteritis": 9.109378620817504, "Glomerulonephritis": 11.684935902526489, "Glucocorticoid deficiency": 93.33687687709478, "Granuloma": 6.016820916352349, "Guillain-Barre syndrome": 7.194192879250318, "Haemophagocytic lymphohistiocytosis": 11.841191342117146, "Hepatic cytolysis": 2.302952221648148, "Hepatic lesion": 4.6931242684799095, "Hepatitis": 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"Immune-mediated hypothyroidism": 44.30409769261316, "Immune-mediated lung disease": 130.25320983857247, "Immune-mediated myasthenia gravis": 105.08007748062978, "Immune-mediated myocarditis": 229.4228018276204, "Immune-mediated myositis": 106.29353756716668, "Immune-mediated nephritis": 268.11830719659974, "Immune-mediated neuropathy": 162.24804260204309, "Immune-mediated pancreatitis": 89.0312362604972, "Immune-mediated thyroiditis": 349.93941749374187, "Immune-mediated uveitis": 237.77810539460356, "Intentional product use issue": 19.045617853119158, "Intestinal perforation": 8.507515880975806, "Iridocyclitis": 29.247058088192155, "Kidney transplant rejection": 7.308882660852478, "Large intestine perforation": 14.1312095025065, "Lichenoid keratosis": 13.016764537000531, "Lipase increased": 4.333568386422847, "Lymphocytic hypophysitis": 558.4777228864215, "Malignant melanoma": 2.930529179041703, "Malignant neoplasm progression": 27.755525810245462, "Melanoma recurrent": 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"Polyarthritis": 11.23661901865747, "Polymyalgia rheumatica": 4.715348616344248, "Polymyositis": 11.325017009955308, "Polyneuropathy": 5.290614128625591, "Prescribed overdose": 3.019148756330173, "Prescribed underdose": 4.603506628675699, "Primary hypothyroidism": 55.39933377858444, "Pulmonary mass": 2.518144752577629, "Pulmonary toxicity": 5.0893657882930885, "Radiation necrosis": 112.07697226903947, "Radiculopathy": 2.3856552349305784, "Rash maculo-papular": 2.661380821192988, "Sarcoidosis": 10.22796560870914, "Secondary adrenocortical insufficiency": 57.4108844572086, "Sjogren's syndrome": 11.430293049913464, "Skin toxicity": 16.50546347547642, "Thyroid disorder": 4.45171356922315, "Thyroiditis": 70.05052279764486, "Thyrotoxic crisis": 16.00775582564924, "Toxic epidermal necrolysis": 3.686371464834559, "Transaminases increased": 2.447696687214037, "Transfusion": 2.311058722106648, "Tubulointerstitial nephritis": 11.279064762142358, "Tumour pseudoprogression": 61.98276320803039, "Type 1 diabetes mellitus": 39.60417912390341, "Uveitis": 10.417910022718075, "Vasculitis": 2.4205366342644146, "Vitiligo": 112.66543173819584, "Vogt-Koyanagi-Harada disease": 30.65577505972935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/595.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/595.json
index 9ad69da8d4b..e54930bd8eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/595.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/595.json
@@ -1 +1 @@
-{"Abortion induced ": 9.162201457621572, "Abortion spontaneous ": 12.24250372988332, "Acquired immunodeficiency syndrome ": 65.64099724312108, "Adverse event ": 13.672767539142034, "Alanine aminotransferase increased ": 6.043357164094914, "Amylase increased ": 5.3371456338815255, "Aphthous ulcer ": 2.501575915045517, "Ascites ": 3.734869467185293, "Aspartate aminotransferase increased ": 5.150247799503328, "Atypical mycobacterial infection ": 22.62733494897861, "Blood HIV RNA increased ": 39.31373695329639, "Blood creatine phosphokinase increased ": 3.477553295064985, "Bronchitis chronic ": 20.98660208660462, "CD4 lymphocytes decreased ": 26.003501328086987, "Caesarean section ": 36.925571071590014, "Cardiac murmur ": 8.520292731590207, "Cholecystitis ": 5.510024181886348, "Cholelithiasis ": 5.1784553714505845, "Cholestasis ": 2.490338253774196, "Circumstance or information capable of leading to medication error ": 5.293320770679062, "Coma ": 2.278509604914939, "Congenital choroid plexus cyst ": 266.1014655127313, "Congenital mitral valve incompetence ": 373.7811060545165, "Cushing's syndrome ": 11.231368778758927, "Cytomegalovirus infection ": 4.535876322948589, "Depression ": 2.0639384723199274, "Depressive symptom ": 11.597591479885814, "Dermatitis exfoliative generalised ": 3.798553611684029, "Drug interaction ": 2.310327312569482, "Drug reaction with eosinophilia and systemic symptoms ": 17.624554934903053, "Drug resistance ": 5.38515577992749, "Dyslipidaemia ": 6.097321143873284, "Dysphagia ": 5.4722149076176, "Dysphoria ": 8.71449070251109, "Encephalopathy ": 2.0612704461569376, "Endotracheal intubation ": 10.435015647090175, "Eosinophil count increased ": 3.574002247098945, "Eosinophilia ": 5.480044544994774, "Epididymitis ": 42.35530313205707, "Erectile dysfunction ": 3.071741528128123, "Exposure during pregnancy ": 10.722559134582214, "Foetal disorder ": 53.33145267081153, "Foetal exposure during pregnancy ": 19.56125128549391, "Foetal growth restriction ": 12.554921768447336, "Gastric ulcer ": 3.526647371371422, "Gastrointestinal tube insertion ": 67.17348963327188, "Gastrostomy ": 37.44770735181053, "Genotype drug resistance test positive ": 19.160371032956075, "Gynaecomastia ": 2.9017703011169007, "HIV infection ": 26.228616703695025, "Haemolytic anaemia ": 2.8637396476965136, "Haemorrhoids ": 3.199122225151042, "Hallucination, auditory ": 3.1728835138025038, "Hemivertebra ": 480.74761012803054, "Hepatic cirrhosis ": 2.346150348155201, "Hepatic cytolysis ": 12.560668733302348, "Hepatic failure ": 3.980495514478459, "Hepatitis ": 4.0609684490335285, "Hepatitis acute ": 3.0026870387222675, "Hepatitis toxic ": 6.906792872458438, "Hepatocellular injury ": 4.159450809627482, "Hernia ": 6.804357810188088, "Herpes simplex ": 6.228646950000963, "Hyperbilirubinaemia ": 7.20478294102445, "Hyperlipidaemia ": 2.985642116493356, "Hypertriglyceridaemia ": 5.462641043151266, "Immune reconstitution inflammatory syndrome ": 55.17842015193536, "Incorrect route of product administration ": 3.946916895007422, "Jaundice ": 3.0506423672595133, "Leukocytosis ": 2.2313904262082334, "Lipase increased ": 4.41054915562292, "Lipodystrophy acquired ": 43.97566010068277, "Live birth ": 3.944480221883075, "Liver disorder ": 3.51379628327106, "Liver function test increased ": 2.995057419059889, "Liver injury ": 2.133136484320288, "Low birth weight baby ": 15.759877556169904, "Lymphoma ": 5.141574378086152, "Maternal drugs affecting foetus ": 91.35380809590296, "Maternal exposure during pregnancy ": 11.888837358995266, "Maternal exposure timing unspecified ": 8.722990414245237, "Metabolic acidosis ": 3.129901270487822, "Myopathy ": 4.122208270356127, "Myositis ": 8.930839917029676, "Neoplasm malignant ": 2.0183941028081787, "Nephrolithiasis ": 2.047924234110237, "Neuropathy peripheral ": 2.822272546970999, "Neurotoxicity ": 3.297971421175697, "Nightmare ": 2.226080948038596, "No adverse event ": 4.618797466770805, "Osteonecrosis ": 2.1202904779640805, "Pancreatic mass ": 76.30225936932983, "Pancreatitis ": 2.135222387905285, "Pancreatitis acute ": 3.35181563404807, "Paralysis ": 2.2453383424932265, "Pathogen resistance ": 4.723258805631885, "Pericardial excision ": 302.50208192980966, "Peritonitis ": 3.822973430022648, "Pneumocystis jirovecii pneumonia ": 9.502252732514217, "Premature baby ": 12.093646925864116, "Premature delivery ": 11.003633827803116, "Premature labour ": 22.636597583884907, "Premature rupture of membranes ": 27.886813253642085, "Psychiatric decompensation ": 43.94282658421839, "Radiation skin injury ": 87.48984981283252, "Renal colic ": 9.77102354747226, "Renal disorder ": 2.0957692578020204, "Renal tubular disorder ": 10.860895955616668, "Respiratory distress ": 4.076777588753494, "Rhabdomyolysis ": 5.519433782463867, "Shock ": 2.222111338120247, "Small for dates baby ": 51.737514199448384, "Stillbirth ": 28.644168483602567, "Toxic skin eruption ": 2.8747360995195352, "Treatment noncompliance ": 3.653637147819361, "Vaginal discharge ": 2.997688628708564, "Ventricular hypertrophy ": 25.409631078271623, "Ventricular septal defect ": 18.74448073602423, "Viral load increased ": 10.083610546482534, "Viral mutation identified ": 21.07158443967743, "Virologic failure ": 14.332766554276567, "Volvulus ": 119.36599752473684, "Vulvovaginal burning sensation ": 16.996612894485715, "Wrong technique in product usage process ": 3.390004166111179}
\ No newline at end of file
+{"Acidosis": 3.19258373693702, "Acute kidney injury": 11.958328500161532, "Adjustment disorder": 11.864618588958349, "Affect lability": 2.239939030146136, "Angioedema": 5.969298027062175, "Anuria": 6.395079655963421, "Aortic aneurysm": 7.628220743712314, "Arteriosclerosis coronary artery": 3.5859000766069, "Atrial fibrillation": 2.9214315256690147, "Atrioventricular block first degree": 7.00850753482841, "Autoimmune hepatitis": 4.1307925051756245, "Blood calcium abnormal": 24.73191768451817, "Blood immunoglobulin E increased": 14.168890113224784, "Blood potassium increased": 6.435437934543185, "Blood pressure decreased": 2.2319750295435923, "Blood pressure inadequately controlled": 10.563412562667695, "Blood pressure increased": 2.835196114380726, "Blood pressure systolic increased": 5.592911012115222, "Blood sodium decreased": 3.6257053742040894, "Blood thyroid stimulating hormone abnormal": 45.9891528125131, "Body temperature decreased": 4.212431284272316, "Bradycardia": 3.619844977483582, "Brain natriuretic peptide abnormal": 169.5080842160149, "Bundle branch block left": 13.32397131700644, "Bundle branch block right": 9.853010291316506, "Cardiac failure chronic": 7.355031865143697, "Cardio-respiratory arrest": 4.064952929141512, "Cardiogenic shock": 5.037826818911573, "Cardiomegaly": 4.026338499462886, "Cell death": 22.00405209910552, "Choking": 2.3272563654825715, "Cholestasis": 3.539711827522515, "Concussion": 5.549178584198931, "Conduction disorder": 19.92712319398857, "Coordination abnormal": 2.2069641789403747, "Dehydration": 3.490111366465156, "Drug interaction": 3.389479153505028, "Drug reaction with eosinophilia and systemic symptoms": 2.2735509593897856, "Dysgeusia": 2.042372789268117, "Dyslipidaemia": 7.435931195961746, "Dysmetria": 134.92989091020652, "Eczema": 3.2869846394520734, "Ejection fraction decreased": 3.929027789832991, "Electrocardiogram QRS complex abnormal": 97.0310900613415, "Electrocardiogram QT prolonged": 3.7484294569976098, "Electrolyte imbalance": 3.688027549686892, "Eosinophilia": 5.285994348254948, "Expanded disability status scale score increased": 97.23315952462826, "Extra dose administered": 3.3056372428490173, "Extrapyramidal disorder": 2.114318540252831, "Extrasystoles": 6.926790779835981, "Fall": 3.863619431515072, "Fluid intake reduced": 10.47750429717237, "Fractured coccyx": 45.02893113078954, "Gait spastic": 545.6683246105284, "Goitre": 10.528454952190708, "Gout": 2.188177064547534, "Haematuria": 2.768685900823205, "Hemiparesis": 2.7163461528893955, "Hemiplegia": 3.2293644339674965, "Hepatic cytolysis": 2.135199549619509, "Hepatic failure": 2.7390226056209133, "Hiatus hernia": 2.240430234191863, "Hypercalcaemia": 3.228570718867339, "Hyperkalaemia": 16.40772970406653, "Hypertension": 2.0954739703110423, "Hyperuricaemia": 5.005433905653601, "Hypokalaemia": 3.857191535637191, "Hypokinesia": 8.09776737822522, "Hypomagnesaemia": 3.911402930919412, "Hyponatraemia": 10.27569665805074, "Hypophagia": 3.96570591413869, "Hypotension": 6.636604953952929, "Hypovolaemia": 4.608087195934704, "Inappropriate antidiuretic hormone secretion": 3.073558305953341, "Insulinoma": 188.33467845780336, "Lactic acidosis": 8.469649436089473, "Left ventricular dilatation": 32.987062152563816, "Leukocytosis": 2.4007062342222567, "Lip swelling": 2.364061046432881, "Lymphoedema": 4.704948622008581, "Lymphopenia": 9.354812321814732, "Metabolic acidosis": 3.1010784619048923, "Mitral valve incompetence": 6.211170183147972, "Muscle spasticity": 16.244026615742023, "Muscular weakness": 2.541352237650241, "Musculoskeletal discomfort": 9.953365071502423, "N-terminal prohormone brain natriuretic peptide abnormal": 400.94499438346753, "Nodal rhythm": 13.49443218263164, "Obstructive airways disorder": 2.5180717189263224, "Obstructive sleep apnoea syndrome": 34.4898290623038, "Oedema peripheral": 2.937148033792881, "Oliguria": 3.6716842470271143, "Orthostatic hypotension": 11.571607192751546, "Oxygen saturation increased": 128.9482607467275, "Pemphigoid": 5.745747651360943, "Photosensitivity reaction": 2.862349617962733, "Poisoning": 4.114685025399158, "Polydipsia": 5.399581495360236, "Product substitution issue": 15.6367401964026, "Pulmonary arterial pressure abnormal": 167.3149328719622, "Pulmonary granuloma": 33.05367305716744, "Rales": 4.144111679596472, "Renal impairment": 3.02852599958778, "Renal tubular necrosis": 8.814977681348017, "Rhabdomyolysis": 3.0272445906373364, "Shock": 2.259259824064036, "Sinus arrest": 9.985936513252224, "Sinus bradycardia": 9.246055247944906, "Sinus node dysfunction": 7.119084460301326, "Sleep apnoea syndrome": 2.5623859905842776, "Supraventricular extrasystoles": 20.880086495906045, "Swollen tongue": 3.1750382884388038, "Tachypnoea": 3.2763636681178534, "Therapeutic response unexpected": 4.408580087441388, "Thyroiditis": 5.78630768753406, "Torsade de pointes": 11.290885564312942, "Tricuspid valve incompetence": 10.79322902873088, "Troponin increased": 5.932421160486333, "Tubulointerstitial nephritis": 2.857486746749439, "Urinary incontinence": 6.378393739002189, "Urine abnormality": 47.405342593667335, "Urine output decreased": 6.310746909011693, "Ventricular fibrillation": 5.353085921616906, "Ventricular hypokinesia": 9.683128779864218, "Wrong patient received product": 25.572174983357847, "Wrong product administered": 2.127178100957832, "Xerosis": 27.237514801319797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/596.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/596.json
index dcab0c0e146..e5e69793ccb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/596.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/596.json
@@ -1 +1 @@
-{"Anaphylactoid reaction ": 19.088555070127462, "Blood cholesterol increased ": 5.851026675786622, "Blood creatine phosphokinase increased ": 5.515483665600753, "Blood creatinine increased ": 3.748518540921511, "Blood glucose abnormal ": 20.3566449972741, "Blood glucose increased ": 8.15665935778768, "Blood pressure decreased ": 3.3395468023104846, "Blood urea increased ": 27.438388995160302, "Cholestasis ": 10.343487952075716, "Diabetes mellitus ": 5.676870603236688, "Diabetes mellitus inadequate control ": 7.786595303256626, "Drug interaction ": 2.034121842989637, "Glycosylated haemoglobin increased ": 31.151325040449557, "Hyperglycaemia ": 5.706997139697428, "Hyperkalaemia ": 4.729444417139543, "Hypoglycaemia ": 19.694263748522214, "Renal failure ": 2.082694021944888}
\ No newline at end of file
+{"Acne": 8.154198755526084, "Acquired gene mutation": 69.7042989401872, "Acute respiratory distress syndrome": 3.937171148402339, "Acute respiratory failure": 6.8508167402690034, "Alanine aminotransferase increased": 2.495375072118109, "Aspartate aminotransferase increased": 2.36692328552314, "Atelectasis": 2.4266284598894226, "Brain neoplasm": 4.505140404453085, "Brain oedema": 2.976459914054294, "Carcinoembryonic antigen increased": 27.00912365139867, "Cerebral disorder": 3.181319889664957, "Cerebral infarction": 4.390647290760168, "Chest X-ray abnormal": 4.587924595632598, "Cutaneous symptom": 34.78099360469639, "Cystitis haemorrhagic": 24.063605984710385, "Death": 2.036537509337825, "Decreased appetite": 2.7224994868149426, "Dermatitis": 6.059090348483822, "Dermatitis acneiform": 54.42788815540443, "Diarrhoea": 3.431921919353881, "Disease progression": 7.2164889283722, "Disseminated intravascular coagulation": 5.397030623116333, "Drug eruption": 2.6541288295745358, "Drug resistance": 70.67642715786374, "Drug tolerance": 16.780137723758106, "Drug-induced liver injury": 3.395271019082301, "Dry skin": 8.01838755447787, "EGFR gene mutation": 107.23376182237224, "Eczema": 2.935566774734069, "Enterocolitis": 5.2064274348912765, "Gastric ulcer": 2.2380691972563773, "Gastrointestinal perforation": 5.0569163625333, "Gene mutation": 30.909304431817933, "Glossitis": 7.513602512433928, "Haematuria": 2.656481204132464, "Haemoptysis": 4.967856209861063, "Hepatic cytolysis": 2.3240790738734174, "Hepatic function abnormal": 17.140323775773716, "Hepatotoxicity": 2.3314064927057734, "Hydrothorax": 39.81332002725986, "Hypertransaminasaemia": 6.531480852162676, "Ileus": 4.679579289264152, "Ingrowing nail": 21.533846927067938, "Interstitial lung disease": 76.98093674836446, "Intestinal obstruction": 2.2174715403769296, "Leukoencephalopathy": 9.047228067410376, "Liver disorder": 12.835000063960898, "Liver function test abnormal": 2.463257788588159, "Liver function test increased": 2.6305809497949, "Lung carcinoma cell type unspecified recurrent": 39.052140692189056, "Lung disorder": 26.01572389184868, "Lung infiltration": 2.9293397521386213, "Lung neoplasm malignant": 3.717607999085944, "Lymphangiosis carcinomatosa": 70.33819700889768, "Malignant neoplasm progression": 24.02795548612873, "Malignant pleural effusion": 29.596189572494023, "Metastases to bone": 24.143152079819867, "Metastases to central nervous system": 80.0331746628135, "Metastases to liver": 6.638260761547869, "Metastases to lung": 8.774142922998356, "Metastases to lymph nodes": 13.49867076149224, "Metastases to meninges": 79.9672614942064, "Metastases to pleura": 33.3072167061144, "Metastases to spine": 11.360625521153604, "Metastasis": 31.50917039552248, "Mouth ulceration": 2.9457374622225267, "Nail disorder": 11.708200467416654, "Neoplasm progression": 2.999499742324912, "Non-small cell lung cancer": 4.371656697444121, "Non-small cell lung cancer recurrent": 145.3852755723312, "Onychoclasis": 7.312797983547702, "Paronychia": 110.48531786560513, "Pericardial effusion": 3.785930921858004, "Peritonitis": 4.753691269167062, "Pleural effusion": 8.540099783856812, "Pneumatosis intestinalis": 22.450609301793232, "Pneumonia": 2.139428720723449, "Pneumonia aspiration": 2.309092362423352, "Pneumonia bacterial": 10.327780174809508, "Pneumonitis": 6.517559829522712, "Pneumothorax": 7.775588441863413, "Pulmonary alveolar haemorrhage": 5.783167906744686, "Pulmonary fibrosis": 2.571176689742857, "Pulmonary mass": 3.188748393657633, "Pulmonary toxicity": 6.662793842786507, "Purpura": 2.414375016645368, "Radiation pneumonitis": 56.526177196016455, "Rash": 3.925167329263153, "Rash pustular": 6.458981539309405, "Respiratory failure": 4.932419543275989, "Seborrhoeic dermatitis": 13.181554866463816, "Skin disorder": 6.348554775618841, "Skin exfoliation": 3.332686353391652, "Skin fissures": 8.94937851549259, "Skin toxicity": 11.147492837682323, "Skin ulcer": 3.319389773588747, "Small cell lung cancer": 17.97279345992964, "Stomatitis": 6.556163017751702, "Therapy cessation": 4.548772475714912, "Transaminases increased": 4.745812062999316, "Tumour marker increased": 11.504208316702814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/597.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/597.json
index b88c03e1055..261f1b77710 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/597.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/597.json
@@ -1 +1 @@
-{"Asthenia ": 3.367752210476369, "Off label use ": 4.266268151282147}
\ No newline at end of file
+{"Acute myeloid leukaemia": 7.017169935799589, "Adenocarcinoma of colon": 17.625797895936913, "Alveolar rhabdomyosarcoma": 808.736956470952, "Anaemia": 4.215375614900895, "Ascites": 2.860073684042282, "Bacteraemia": 3.017441511038173, "Bone marrow failure": 4.142722585621781, "Carcinoembryonic antigen increased": 16.184588847757176, "Cholangitis": 10.23085914144173, "Cholinergic syndrome": 45.525452936625705, "Chronic myeloid leukaemia": 8.464351500942604, "Clostridium difficile colitis": 2.4538811677835928, "Clostridium difficile infection": 2.9131686399464622, "Colitis": 3.787900316862454, "Colon cancer": 2.7028108512053883, "Colon cancer metastatic": 33.91054722486251, "Colorectal cancer metastatic": 84.31223414303267, "Conjunctivitis": 2.425030026666377, "Constipation": 2.4983805588557377, "Cytopenia": 2.532114834186733, "Decreased appetite": 2.9418663064604385, "Dehydration": 2.456694039454963, "Dermatitis acneiform": 29.68723484362347, "Diarrhoea": 5.09543778484576, "Disease progression": 10.469483500145282, "Dry skin": 3.8671319460963463, "Dysarthria": 7.501021096371077, "Ejection fraction decreased": 3.600483848459833, "Enteritis": 9.121932925422524, "Febrile neutropenia": 14.530857300177512, "Gastrointestinal anastomotic leak": 173.54186699462883, "Gastrointestinal toxicity": 38.51108397261213, "Gene mutation": 18.48866461171893, "General physical health deterioration": 2.200899480108897, "Haematotoxicity": 32.63859910568032, "Hepatic encephalopathy": 2.515806126686099, "Hiccups": 5.816193383212857, "Hyperammonaemia": 7.326145207621402, "Hyperammonaemic encephalopathy": 12.268659875385437, "Hypertransaminasaemia": 10.540164607175209, "Hypokalaemia": 2.204794793592117, "Hypomagnesaemia": 13.321254543281672, "Hypophagia": 2.190832131986965, "Interstitial lung disease": 2.6588924243645606, "Intestinal obstruction": 2.811664417113687, "Laryngospasm": 4.688715157889379, "Leukoencephalopathy": 7.302081364250778, "Leukopenia": 5.280752917025, "Lymphopenia": 2.220622961922506, "Malignant neoplasm progression": 5.219945447224868, "Metastases to bone": 5.862733569731827, "Metastases to central nervous system": 5.107361687359404, "Metastases to liver": 15.957424143839791, "Metastases to lung": 12.569450066620549, "Metastases to lymph nodes": 8.791000689432286, "Metastases to meninges": 23.142383242170787, "Metastases to peritoneum": 23.411787841752663, "Mucosal inflammation": 16.56662714157192, "Myelodysplastic syndrome": 4.00334406871786, "Myelosuppression": 8.365104338463475, "Neoplasm progression": 2.9750941441932506, "Neuropathy peripheral": 10.574322564997033, "Neurotoxicity": 16.671000465264665, "Neutropenia": 19.41761377274718, "Neutropenic colitis": 18.1347637326855, "Neutropenic sepsis": 7.592136953590644, "Neutrophil count decreased": 7.71551324208614, "Pancreatic carcinoma": 2.118938546386959, "Pancreatic carcinoma metastatic": 17.025192850067153, "Pancreatic carcinoma recurrent": 178.41092115362937, "Pancytopenia": 2.555693333418413, "Paronychia": 25.954140628263552, "Peripheral sensory neuropathy": 24.730800273427302, "Peritonitis": 3.40998473978924, "Polyneuropathy": 4.643550002998962, "Portal hypertension": 9.865010972032332, "Proteinuria": 3.5848223778884454, "Prothrombin time prolonged": 3.5908554755964923, "Pulmonary mass": 3.7491853002540503, "Rash pustular": 4.362594473551276, "Skin toxicity": 32.02736682467039, "Small intestinal obstruction": 8.470801694405056, "Stomatitis": 7.989059968255333, "Temperature intolerance": 4.283016265391968, "Therapeutic response decreased": 2.70123287622265, "Therapy partial responder": 13.26078800277974, "Thrombocytopenia": 8.121414134858123, "Transaminases increased": 2.119674616413591, "Vomiting": 2.8055391047270053, "White blood cell count decreased": 3.2795673509136694}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/598.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/598.json
index 98c88a5168b..1225edb1eaf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/598.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/598.json
@@ -1 +1 @@
-{"Anaemia ": 4.288756872469929, "Angina pectoris ": 25.267803954709017, "Angina unstable ": 41.09930766440105, "Blood potassium increased ": 29.645190118139265, "Blood pressure decreased ": 6.565062096543902, "Blood pressure systolic decreased ": 83.14769727377978, "Bradycardia ": 12.921994780117796, "Cardiac failure ": 17.531825338352988, "Contusion ": 12.236948448083806, "Dilated cardiomyopathy ": 92.9027951113865, "Drug interaction ": 6.116985375865525, "Dyspnoea exertional ": 4.994070997371184, "ECG signs of myocardial ischaemia ": 1124.7900986023074, "Ejection fraction decreased ": 24.22491825993602, "Electrocardiogram QT prolonged ": 14.944706497890229, "Fluid retention ": 32.60789961809711, "Glomerular filtration rate decreased ": 26.640445622249874, "Hypotension ": 11.063205398549536, "Intentional self-injury ": 17.022503347519358, "Mental disorder ": 9.96525652703948, "Mitral valve incompetence ": 35.82421899676855, "N-terminal prohormone brain natriuretic peptide increased ": 80.44381262534556, "Oedema peripheral ": 18.086521302271574, "Personality disorder ": 98.99076893959575, "Presyncope ": 19.74648643544044, "Psoriasis ": 22.570009125551728, "Pulmonary oedema ": 33.54157949263872, "Rales ": 30.680095877063952, "Schizophrenia ": 36.06121745877247, "Sinus arrest ": 169.8045097608625, "Sinus bradycardia ": 61.21954376347272, "Suicide attempt ": 5.841694981373992, "Torsade de pointes ": 14.452431858859548, "Treatment failure ": 5.770739571380053, "Venous pressure jugular increased ": 909.621439087268, "Ventricular arrhythmia ": 45.93901715551617, "Ventricular dysfunction ": 749.0346955618561, "Ventricular extrasystoles ": 17.103482821467775, "Ventricular fibrillation ": 13.381774976491432}
\ No newline at end of file
+{"Adrenal insufficiency": 5.865631365929076, "Adverse event": 5.082056096883587, "Adverse reaction": 6.436463579806, "Amnesia": 2.927749761074914, "Ankle fracture": 6.787211368988364, "Antipsychotic drug level increased": 41.17781339224688, "Arthritis infective": 22.43218102530886, "Asthma": 2.321356897265448, "Atrial fibrillation": 2.0735709608400525, "Atrioventricular block first degree": 25.107874759829723, "Blood iron decreased": 15.52186621107935, "Brain fog": 2.779377747333277, "Calciphylaxis": 98.92084155750275, "Cardiac arrest": 2.284674302592812, "Cardiac failure": 2.1960927621646795, "Chronic obstructive pulmonary disease": 4.816072492132301, "Chronic spontaneous urticaria": 53.846276927701176, "Clonus": 17.820124537441547, "Coagulopathy": 3.467855360613948, "Completed suicide": 4.634331148847398, "Constipation": 2.265793084912798, "Dementia Alzheimer's type": 17.655455866590955, "Drug hypersensitivity": 2.0024979885400285, "Drug interaction": 2.295869295678753, "Electrocardiogram QT prolonged": 3.117020401875258, "Exposure during pregnancy": 3.8262984893890457, "Fall": 2.4523068284851908, "Foetal exposure during pregnancy": 12.592708703253534, "Full blood count abnormal": 2.378942861899194, "Gastrooesophageal reflux disease": 3.377701870351156, "Generalised oedema": 4.6298974405027336, "Haemoglobin decreased": 2.157624216494204, "Head discomfort": 5.172275441735192, "Heart rate decreased": 3.32877661780945, "Hip surgery": 28.532415485192693, "Hyperkalaemia": 2.1267638375602296, "Hypersomnia": 4.890759305570806, "Hyperventilation": 6.859741536361875, "Hypotension": 2.0696403883630103, "Implant site erosion": 222.6172074230019, "Implant site infection": 82.1613590858906, "Live birth": 7.946739229432927, "Low birth weight baby": 10.86723075929572, "Lower limb fracture": 8.687233850288493, "Lower respiratory tract infection": 2.410506637635884, "Maternal exposure during pregnancy": 4.366236687124859, "Meningitis": 8.771872798563658, "Micturition disorder": 19.86753372622351, "Muscle spasticity": 10.15105978166584, "Obesity": 4.843594490924652, "Pallor": 2.475175532476021, "Premature baby": 17.626962712624604, "Premature delivery": 6.633296134515385, "Pulmonary hypertension": 3.700827929861738, "Purulent discharge": 32.42946803969209, "Rash macular": 2.1098308960614007, "Respiratory distress": 5.084437596849511, "Restlessness": 2.440893830961534, "Rib fracture": 4.399690000498744, "Sinus disorder": 13.786226299129686, "Sinusitis fungal": 125.0468043360552, "Skin discolouration": 3.5987222533846017, "Sleep disorder due to a general medical condition": 7.098079055884357, "Sputum discoloured": 17.353996139877957, "Talipes": 16.597253085404695, "Toxicity to various agents": 4.798046025481185, "Umbilical cord around neck": 115.38737303967063, "Vaginal infection": 24.510645159189917, "Viral infection": 3.5642238684080048, "Wheezing": 3.325808651664118, "Wound dehiscence": 39.9867188551227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/599.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/599.json
index 424a7a03e8f..8d42ddaff50 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/599.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/599.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 15.199951144193657, "Dry eye ": 77.82005651515487, "Insomnia ": 9.916105429983393, "Rash ": 6.043010574963553}
\ No newline at end of file
+{"Plasma cell myeloma": 120.19680629071564}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/6.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/6.json
index c8ab0030ee3..aecb0a6be33 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/6.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/6.json
@@ -1 +1 @@
-{"Anaemia ": 2.4617573956389687, "Blood bilirubin increased ": 6.925106015555614, "Breast cancer metastatic ": 93.15999432842683, "Diarrhoea ": 3.853968209491729, "Disease progression ": 3.1412143460413438, "Malignant neoplasm progression ": 17.71103368606872, "Metastases to bone ": 81.60225083279639, "Metastases to liver ": 45.60456660337498, "Metastases to lung ": 37.63510260335623, "Metastatic neoplasm ": 107.1257911622265, "Myelosuppression ": 20.66017116223991, "Neuropathy peripheral ": 3.653176115903396, "Neutropenia ": 4.333271677969338, "Neutrophil count decreased ": 5.8981201708660285, "Platelet count decreased ": 5.768634076520544, "Tumour marker increased ": 96.50616766760608, "White blood cell count decreased ": 3.8952560166661834}
\ No newline at end of file
+{"Disease progression": 102.944575958747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/60.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/60.json
index 58121c607a9..d511df3e605 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/60.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/60.json
@@ -1 +1 @@
-{"Completed suicide ": 153.44599510511185, "Toxicity to various agents ": 84.87282914211947}
\ No newline at end of file
+{"Blood creatinine increased": 2.401949180903367, "Blood glucose abnormal": 9.06533303656946, "Blood glucose increased": 5.336804459230629, "Bone lesion": 144.37396459988793, "Breast cancer": 18.173663496496665, "Breast cancer metastatic": 78.26872288510475, "Colitis": 12.057460787261917, "Decreased appetite": 3.3957151388778506, "Diabetes mellitus": 6.287278265310076, "Diabetic ketoacidosis": 13.721487383478536, "Diarrhoea": 3.353386602840578, "Disease progression": 3.180679690230368, "Glomerular filtration rate decreased": 8.32963304444604, "Hepatic lesion": 36.89639442563308, "Hyperglycaemia": 66.83909950677229, "Ketoacidosis": 12.542344745093494, "Malignant neoplasm progression": 22.57815466307848, "Metastases to bone": 86.4907984598958, "Metastases to central nervous system": 24.052704377612688, "Metastases to liver": 54.324832692377214, "Metastases to lung": 23.682241113965883, "Mucosal inflammation": 7.85130941763764, "Non-small cell lung cancer metastatic": 332.6209519828068, "Rash": 4.627695805729471, "Rash maculo-papular": 4.030981195593474, "Therapy partial responder": 19.354323675007983, "Weight decreased": 3.1720607052156304}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/600.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/600.json
index b87382a17fa..5bd9f253489 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/600.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/600.json
@@ -1 +1 @@
-{"Back pain ": 2.302881684585676, "Chronic fatigue syndrome ": 55.21397282854985, "Erythema ": 2.746536531545758, "Hypoaesthesia ": 3.163511475907124, "Migraine ": 3.260808789662923}
\ No newline at end of file
+{"Anaemia": 4.531429335375327, "C-reactive protein increased": 3.014901573046446, "Cerebral haemorrhage": 8.576455355686022, "Drug interaction": 2.894287993349752, "Epistaxis": 3.814543015058492, "Eye haemorrhage": 10.8854025500992, "Gastric haemorrhage": 21.5939574161558, "Gastric ulcer haemorrhage": 115.956823658567, "Gastritis haemorrhagic": 228.4518689559682, "Gastrointestinal haemorrhage": 39.32767285319074, "Haematemesis": 20.046321897187752, "Haematoma": 12.559726952073577, "Haematuria": 4.93785051987726, "Haemoglobin decreased": 3.82535811680806, "Haemoptysis": 6.329459482389591, "Haemorrhage": 7.595728311471835, "Haemorrhage intracranial": 9.673882097408493, "Hepatic enzyme increased": 3.237199686355869, "Leukopenia": 3.60424384112369, "Melaena": 28.607348225050423, "Pallor": 4.492885612179072, "Pancytopenia": 4.426080489926366, "Thrombocytopenia": 6.908430678777886}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/601.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/601.json
index 432160685e7..c12ec9e8224 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/601.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/601.json
@@ -1 +1 @@
-{"Actinic keratosis ": 16.530742891415514, "Acute coronary syndrome ": 2.21174276184592, "Acute graft versus host disease ": 2.976029861665217, "Acute graft versus host disease in skin ": 10.98061870651816, "Acute leukaemia ": 31.334361788677946, "Acute lymphocytic leukaemia ": 4.3067977696433815, "Acute myeloid leukaemia ": 29.87365126298891, "Acute myeloid leukaemia recurrent ": 5.066241965662304, "Acute respiratory distress syndrome ": 2.0858421150996, "Adenocarcinoma ": 6.82629803147627, "Alanine aminotransferase abnormal ": 4.0961994334941085, "Alveolar proteinosis ": 60.10570643809699, "Anaemia ": 9.681513657734769, "Ascites ": 4.266644126197976, "Aspergillus infection ": 4.388622574400241, "Atypical mycobacterial infection ": 13.563233624924422, "Autoimmune haemolytic anaemia ": 3.059429832041717, "B-cell lymphoma ": 4.580203866820011, "BK virus infection ": 4.5330797831799, "Bacteraemia ": 4.077083447590366, "Basal cell carcinoma ": 14.183000514784224, "Basophil count increased ": 47.13475456926137, "Blast cell count increased ": 170.59371217443262, "Blast cell crisis ": 59.608178156650254, "Blast cells present ": 77.27963742127534, "Blood bilirubin abnormal ": 9.85098635497116, "Blood bilirubin increased ": 2.0635651738702587, "Blood creatinine abnormal ": 5.264979656927025, "Blood disorder ": 2.4033965640844133, "Blood fibrinogen decreased ": 8.740466280210347, "Blood lactate dehydrogenase increased ": 12.78110612761754, "Blood potassium increased ": 4.469456395365851, "Blood test abnormal ": 2.0883559371075444, "Blood uric acid increased ": 2.064666973283669, "Bone marrow disorder ": 4.94991667788169, "Bone marrow failure ": 3.019366158226479, "Bone marrow oedema ": 9.922623982136145, "Bone pain ": 2.4742777383158425, "Bowen's disease ": 62.51719957612444, "Bronchopulmonary aspergillosis ": 3.0768655645493865, "COVID-19 pneumonia ": 2.029987564586436, "Cachexia ": 4.0974163910647965, "Cardiac failure ": 3.2418268280113054, "Cardiac tamponade ": 6.202155371558426, "Cerebral atrophy ": 2.94734330389285, "Chronic graft versus host disease ": 7.726530333577084, "Chronic lymphocytic leukaemia ": 4.375597144978277, "Chronic myeloid leukaemia ": 7.045606775168763, "Concomitant disease aggravated ": 18.30817143073069, "Concomitant disease progression ": 4.968820546045316, "Coronavirus infection ": 7.737447925725832, "Creatinine renal clearance decreased ": 2.864971886958477, "Cystitis haemorrhagic ": 2.962974964257364, "Cytokine storm ": 25.907490161652994, "Cytomegalovirus infection ": 4.120587164646631, "Cytomegalovirus infection reactivation ": 3.0957088155735946, "Cytopenia ": 12.707895161227489, "Death ": 3.006689032703474, "Diffuse large B-cell lymphoma ": 10.12808825827324, "Diffuse large B-cell lymphoma stage IV ": 67.64561622615646, "Disseminated tuberculosis ": 15.509153222710976, "Dysphagia ": 2.1876368523414564, "Early satiety ": 29.29694100482786, "Embolism ": 2.1243556744546503, "Epstein-Barr virus infection ": 7.063563575731819, "Epstein-Barr virus infection reactivation ": 4.17953228095932, "Erysipelas ": 3.112637977200909, "Escherichia sepsis ": 7.086565715302659, "Escherichia urinary tract infection ": 4.222483264128046, "Extramedullary haemopoiesis ": 67.64561622615646, "Fasciitis ": 43.13085105785789, "Fibrosis ": 6.99209824927695, "Full blood count abnormal ": 4.174938442858459, "Full blood count decreased ": 6.866002485008272, "Gamma-glutamyltransferase increased ": 2.019812523132024, "Gastric ulcer ": 2.672390243200144, "Gastric varices haemorrhage ": 26.32532128778129, "Gastrointestinal haemorrhage ": 2.3123365036343437, "General physical condition abnormal ": 6.987425868536882, "General physical health deterioration ": 3.1788712304789164, "Glomerular filtration rate decreased ": 2.7396190427469653, "Graft versus host disease ": 8.90029176339465, "Graft versus host disease in gastrointestinal tract ": 4.947700989967922, "Graft versus host disease in skin ": 6.3151857302981576, "Haematocrit abnormal ": 17.441802451416223, "Haematocrit decreased ": 10.46136745343274, "Haematocrit increased ": 25.10358107547944, "Haematoma ": 2.664438045667437, "Haematoma muscle ": 2.372715717867313, "Haematotoxicity ": 3.142326186994431, "Haemoglobin abnormal ": 13.860381055857294, "Haemoglobin decreased ": 15.274251938544262, "Haemoglobin increased ": 10.489563991646015, "Haemolysis ": 4.443354402810808, "Haemorrhage ": 2.421802344151949, "Haemorrhage subcutaneous ": 2.1028278670910727, "Haemorrhagic diathesis ": 2.2439453542282384, "Haemosiderosis ": 88.3270206100171, "Haptoglobin decreased ": 9.252306126008834, "Hepatitis B reactivation ": 9.476876568668152, "Hepatomegaly ": 6.644585489172268, "Hepatosplenomegaly ": 11.063642454228606, "Hepatotoxicity ": 2.061009489696677, "Herpes virus infection ": 4.387887526162106, "Herpes zoster ": 3.777462339358639, "Hyperkeratosis ": 2.0543411131699485, "Hypertriglyceridaemia ": 3.6152049458251634, "Hyperuricaemia ": 3.1074759607783338, "Hypogammaglobulinaemia ": 3.3704318110371605, "Immunosuppression ": 7.457681043790479, "Inappropriate schedule of product administration ": 2.3987360299331915, "Increased appetite ": 2.3640481543499825, "Infection ": 3.688428738706252, "Iron deficiency ": 2.704818773691545, "Iron overload ": 21.958596629761185, "Kaposi's sarcoma ": 7.694048429168653, "Laboratory test abnormal ": 2.139621419482668, "Leukaemia ": 14.991140403365906, "Leukocytosis ": 11.868743467460938, "Liver abscess ": 4.380022929058129, "Lung neoplasm malignant ": 2.003483681007594, "Lymph node tuberculosis ": 60.97275278868206, "Lymphocyte count decreased ": 4.880386646944058, "Lymphocyte count increased ": 5.885034663283319, "Lymphocytosis ": 6.907672565156201, "Lymphoma ": 3.2886400772214004, "Lymphopenia ": 3.1371209291842708, "Mean cell haemoglobin concentration decreased ": 17.361117034449848, "Mean cell volume decreased ": 14.910970826041302, "Mean cell volume increased ": 13.54089698954817, "Metastases to liver ": 2.0871034853812107, "Metastases to lymph nodes ": 2.305338622748669, "Monocyte count increased ": 4.315617139061603, "Multiple organ dysfunction syndrome ": 2.6163643856469765, "Mycobacterial infection ": 9.09226126479271, "Mycobacterium avium complex infection ": 5.453006197334908, "Myelodysplastic syndrome ": 2.025101666666671, "Myelofibrosis ": 325.718443353204, "Myeloproliferative neoplasm ": 38.99379197621237, "Myositis ": 2.750650369892375, "Necrosis ": 2.7559405163344635, "Neoplasm ": 2.4786002298590435, "Neoplasm skin ": 15.647972769752108, "Neuroendocrine carcinoma of the skin ": 82.92425922340112, "Neutrophil count increased ": 9.5737738024387, "Neutrophil percentage increased ": 11.604024378258543, "Night sweats ": 3.353171352384323, "Oesophageal varices haemorrhage ": 14.852709006818234, "Pancytopenia ": 3.879487509835128, "Platelet count abnormal ": 15.920147433236416, "Platelet count decreased ": 13.068735410011875, "Platelet count increased ": 55.85902523398672, "Platelet disorder ": 7.057734453232928, "Pleural effusion ": 2.266021602565759, "Pneumocystis jirovecii pneumonia ": 5.176793968060559, "Pneumonia ": 2.667213719591924, "Pneumonia fungal ": 3.0143728405718435, "Pneumonitis ": 2.0949123610883578, "Polycythaemia vera ": 152.31551694094267, "Portal hypertension ": 5.502912316308954, "Portal vein thrombosis ": 7.406106254026403, "Post herpetic neuralgia ": 2.260889048951999, "Post procedural haemorrhage ": 4.508040879506992, "Primary myelofibrosis ": 400.4249844935871, "Product supply issue ": 9.658523351269674, "Product use in unapproved indication ": 5.162095336110975, "Progressive multifocal leukoencephalopathy ": 4.5239408838045065, "Pulmonary alveolar haemorrhage ": 2.9836123145226505, "Pulmonary arterial hypertension ": 2.562257135838523, "Pulmonary hypertension ": 5.022630295535064, "Pulmonary mass ": 2.019512198295076, "Pulmonary tuberculosis ": 9.14120829862694, "Pyoderma gangrenosum ": 6.272194798499495, "Rectal cancer ": 4.412952134802672, "Red blood cell count decreased ": 6.557492891615762, "Red blood cell count increased ": 21.947840768986847, "Red cell distribution width increased ": 15.073945535628592, "Respiratory failure ": 2.059714649352986, "Respiratory tract infection ": 4.0705877568871625, "Reticulocyte count increased ": 14.129701593787344, "Second primary malignancy ": 75.7229662116623, "Sepsis ": 3.555975252120705, "Septic shock ": 3.595787377626628, "Serum ferritin increased ": 6.740696760701432, "Skin cancer ": 13.001622865158804, "Skin haemorrhage ": 2.961791512905184, "Skin lesion ": 2.501804836405108, "Skin papilloma ": 4.192325546590464, "Skin ulcer ": 2.114616105004522, "Spleen disorder ": 82.31056767861236, "Splenic infarction ": 22.64741060738836, "Splenic rupture ": 48.17878116022661, "Splenomegaly ": 98.30616730863356, "Squamous cell carcinoma ": 38.301935310868586, "Squamous cell carcinoma of skin ": 30.801730150549943, "Subdural haematoma ": 2.194840061450238, "Sudden death ": 2.0800205949835164, "Terminal state ": 3.481818508214796, "Therapeutic response decreased ": 2.9197190582334964, "Therapy non-responder ": 3.9520866026226575, "Thrombocytopenia ": 8.64868345351827, "Thrombocytosis ": 29.978813834095117, "Thrombotic microangiopathy ": 2.0533983118261814, "Transaminases increased ": 2.22614234615017, "Transformation to acute myeloid leukaemia ": 418.244021212654, "Tuberculosis ": 20.16586588925764, "Tumour lysis syndrome ": 2.997671488307312, "Ulcer ": 3.670730654767126, "Urinary tract infection ": 2.256711457619597, "Varices oesophageal ": 11.494522491983023, "Weight increased ": 3.74843211125026, "White blood cell count abnormal ": 4.445374356989444, "White blood cell count decreased ": 2.4896111222027724, "White blood cell count increased ": 21.374728181539915, "White blood cell disorder ": 9.01802196483206, "Withdrawal syndrome ": 2.076852313926953}
\ No newline at end of file
+{"Abortion induced": 9.153724316416694, "Abortion spontaneous": 12.231171269924342, "Acquired immunodeficiency syndrome": 65.5802673297462, "Adverse event": 13.660110318820315, "Alanine aminotransferase increased": 6.037762618218142, "Amylase increased": 5.332207763079496, "Aphthous ulcer": 2.4992615993303917, "Ascites": 3.731413501676079, "Aspartate aminotransferase increased": 5.145480597602894, "Atypical mycobacterial infection": 22.60640176633081, "Blood HIV RNA increased": 39.27736108716279, "Blood creatine phosphokinase increased": 3.4743352293808982, "Bronchitis chronic": 20.967185771791083, "CD4 lymphocytes decreased": 25.97944322430919, "Caesarean section": 36.891396306511126, "Cardiac murmur": 8.512409421859859, "Cholecystitis": 5.504926426455712, "Cholelithiasis": 5.173663702654479, "Cholestasis": 2.488034166033142, "Circumstance or information capable of leading to medication error": 5.288423693033505, "Coma": 2.2764012267798206, "Congenital choroid plexus cyst": 265.8552842613422, "Congenital mitral valve incompetence": 373.43530172302894, "Cushing's syndrome": 11.220977766039065, "Cytomegalovirus infection": 4.531679682481765, "Depression": 2.0620281054902434, "Depressive symptom": 11.586861159832932, "Dermatitis exfoliative generalised": 3.795039406519604, "Drug interaction": 2.3081886875237587, "Drug reaction with eosinophilia and systemic symptoms": 17.60677404815595, "Drug resistance": 5.380172491526457, "Dyslipidaemia": 6.091680103939657, "Dysphagia": 5.4671494124288245, "Dysphoria": 8.70642763268812, "Encephalopathy": 2.059363379723785, "Endotracheal intubation": 10.425361401651664, "Eosinophil count increased": 3.570695739773754, "Eosinophilia": 5.474973448983155, "Epididymitis": 42.31611709354543, "Erectile dysfunction": 3.068899430058871, "Exposure during pregnancy": 10.712629922107002, "Foetal disorder": 53.2821130758034, "Foetal exposure during pregnancy": 19.543130873268037, "Foetal growth restriction": 12.543304807881617, "Gastric ulcer": 3.521040239531981, "Gastrointestinal tube insertion": 67.11132867204128, "Gastrostomy": 37.41306126457084, "Genotype drug resistance test positive": 19.14264409014666, "Gynaecomastia": 2.899085785998296, "HIV infection": 26.20435061450971, "Haemolytic anaemia": 2.8610902433984724, "Haemorrhoids": 3.1961623961660885, "Hallucination, auditory": 3.169948029630719, "Hemivertebra": 480.30284527477977, "Hepatic cirrhosis": 2.3439797942780887, "Hepatic cytolysis": 12.54904209962918, "Hepatic failure": 3.976812235065059, "Hepatitis": 4.057210529643885, "Hepatitis acute": 2.999909162521497, "Hepatitis toxic": 6.900403193211755, "Hepatocellular injury": 4.15439197129471, "Hernia": 6.798062491312155, "Herpes simplex": 6.222884485707275, "Hyperbilirubinaemia": 7.198116353770423, "Hyperlipidaemia": 2.982879970423149, "Hypertriglyceridaemia": 5.457587187879199, "Immune reconstitution inflammatory syndrome": 55.12734084854807, "Incorrect route of product administration": 3.943264942882293, "Jaundice": 3.047819442698998, "Leukocytosis": 2.2293260430751265, "Lipase increased": 4.406468561632863, "Lipodystrophy acquired": 43.93496327232247, "Live birth": 3.940831013802849, "Liver disorder": 3.510544703130953, "Liver function test increased": 2.9922862721656847, "Liver injury": 2.1311628834083733, "Low birth weight baby": 15.745293569733713, "Lymphoma": 5.136817447630272, "Maternal drugs affecting foetus": 91.26929359263696, "Maternal exposure during pregnancy": 11.87782779351381, "Maternal exposure timing unspecified": 8.714920518361666, "Metabolic acidosis": 3.1270053033679903, "Myopathy": 4.118394638502645, "Myositis": 8.922576589883747, "Neoplasm malignant": 2.016526566631625, "Nephrolithiasis": 2.045691091208112, "Neuropathy peripheral": 2.8195749291477834, "Neurotoxicity": 3.294920246030708, "Nightmare": 2.2240212887138915, "No adverse event": 4.614523728513489, "Osteonecrosis": 2.118328262212609, "Pancreatic mass": 76.23166144588866, "Pancreatitis": 2.1332465203652413, "Pancreatitis acute": 3.348714117382291, "Paralysis": 2.2432610287349166, "Pathogen resistance": 4.718889058035986, "Pericardial excision": 302.2222330162271, "Peritonitis": 3.8194366330449774, "Pneumocystis jirovecii pneumonia": 9.493460535813176, "Premature baby": 12.082453096850964, "Premature delivery": 10.99345150372856, "Premature labour": 22.61565144946711, "Premature rupture of membranes": 27.861011607992804, "Psychiatric decompensation": 43.90216758095309, "Radiation skin injury": 87.4089110720285, "Renal colic": 9.761984086275744, "Renal disorder": 2.093521164590357, "Renal tubular disorder": 10.850847695665406, "Respiratory distress": 4.073005068367869, "Rhabdomyolysis": 5.514325403900237, "Shock": 2.220055463372266, "Small for dates baby": 51.689640172356704, "Stillbirth": 28.617664580261952, "Toxic skin eruption": 2.8720764548813, "Treatment noncompliance": 3.650256494998105, "Vaginal discharge": 2.9949153766858427, "Ventricular hypertrophy": 25.386123922697656, "Ventricular septal defect": 18.7271366454741, "Viral load increased": 10.07428098957922, "Viral mutation identified": 21.05208904616732, "Virologic failure": 14.319505325570091, "Volvulus": 119.25554450312762, "Vulvovaginal burning sensation": 16.980888411750303, "Wrong technique in product usage process": 3.386867071096936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/602.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/602.json
index 783f068a369..a7c2649adc5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/602.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/602.json
@@ -1 +1 @@
-{"Abdominal abscess ": 6.532704798762095, "Abdominal hernia ": 4.246133578101267, "Abdominal lymphadenopathy ": 10.352645198801184, "Abnormal loss of weight ": 7.07743946226606, "Abscess drainage ": 16.12936836817677, "Accident ": 4.077428397369374, "Acute kidney injury ": 2.3703684490191037, "Adenocarcinoma pancreas ": 118.27019031322354, "Adrenal adenoma ": 40.57961119185602, "Adrenal disorder ": 7.760835061608442, "Adrenal mass ": 51.4486755151742, "Adverse event ": 7.3105707338232895, "Amylase increased ": 8.181117647102, "Anaemia of chronic disease ": 20.214009215199265, "Aneurysm ": 2.529347612870501, "Angioplasty ": 11.778053954653188, "Ankle operation ": 17.871831434914583, "Anuria ": 2.3122994608737164, "Aortic aneurysm ": 4.494329680254895, "Aortic arteriosclerosis ": 29.015161014734176, "Appendicectomy ": 19.56527879529214, "Arterial disorder ": 17.337857514953527, "Arterial occlusive disease ": 3.056142171303218, "Arteriosclerosis ": 5.585314612301204, "Arteriosclerosis coronary artery ": 6.8364671189082085, "Arthroscopy ": 18.614370943470064, "Ascites ": 2.008981467513166, "Atelectasis ": 14.223958260351814, "Barrett's oesophagus ": 4.858320255899075, "Benign prostatic hyperplasia ": 13.331830678936385, "Bicytopenia ": 3.87294134869196, "Bile duct stenosis ": 31.078639217729645, "Bile duct stent insertion ": 121.48265306869853, "Bile duct stone ": 7.967569967013531, "Biliary dilatation ": 22.496983126525677, "Biliary obstruction ": 27.954482521871714, "Biopsy liver ": 45.94811212194794, "Blood cholesterol abnormal ": 7.850364523430417, "Blood cholesterol increased ": 2.794108429038909, "Blood creatinine abnormal ": 2.974079607251851, "Blood glucose abnormal ": 12.312648526595048, "Blood glucose decreased ": 3.414958301115501, "Blood glucose fluctuation ": 5.73702176649127, "Blood glucose increased ": 5.608937464255798, "Blood lactic acid ": 52.03162005849007, "Blood lactic acid increased ": 2.064413452794065, "Blood magnesium decreased ": 3.2423120843359223, "Blood triglycerides abnormal ": 13.024026602744229, "Blood triglycerides increased ": 3.774069154477545, "Bone lesion ": 3.964075991786188, "Bundle branch block right ": 2.052687411509297, "Calculus bladder ": 11.370737071065593, "Cardiac murmur ": 3.349674733504921, "Cardiac operation ": 6.27055568912444, "Cardiac pacemaker insertion ": 3.721502944049016, "Cardiomegaly ": 2.7831680377747445, "Carpal tunnel decompression ": 21.718846123530312, "Cataract operation ": 11.27158413215527, "Catheter placement ": 6.177573232899661, "Catheterisation cardiac ": 3.061587782552317, "Central venous catheterisation ": 6.006132464685732, "Cerebrovascular accident ": 2.4021105954716453, "Chemotherapy ": 7.72397513842111, "Cholangiocarcinoma ": 8.909702863446293, "Cholangitis ": 7.839497423433308, "Cholecystectomy ": 30.071097306961622, "Cholecystitis ": 5.362700387844019, "Cholecystitis chronic ": 24.61986531921088, "Cholelithiasis ": 12.19815211755869, "Chronic gastritis ": 8.126706467526548, "Circumstance or information capable of leading to medication error ": 10.141646726906476, "Colorectal adenoma ": 10.51235184839325, "Constipation ": 3.062135154922481, "Coronary angioplasty ": 6.778043084729179, "Coronary arterial stent insertion ": 7.868938740092327, "Coronary artery bypass ": 4.457058950477769, "Coronary artery disease ": 3.2301725551153213, "Counterfeit product administered ": 9.336665682361522, "Death ": 2.132988091991107, "Decubitus ulcer ": 6.142129817724489, "Dementia ": 2.130302524146682, "Dementia Alzheimer's type ": 2.200807864547316, "Device occlusion ": 3.158311766301718, "Diabetes mellitus ": 2.9373070610461123, "Diabetes mellitus inadequate control ": 22.949770282321506, "Diabetic complication ": 49.57003998749576, "Diabetic metabolic decompensation ": 13.372696042377507, "Diabetic nephropathy ": 11.182808821009957, "Diabetic neuropathy ": 19.49834522090172, "Diabetic retinopathy ": 2.791674732385608, "Disease complication ": 8.313340450689847, "Diverticulum ": 10.427998186122958, "Diverticulum intestinal ": 18.433687217587597, "Ductal adenocarcinoma of pancreas ": 70.28352840302249, "Duodenitis ": 3.3936206974807925, "Dyslipidaemia ": 3.605746382689284, "Dysphagia ": 6.257790160595537, "Dyspnoea at rest ": 4.1818935395969, "Emphysema ": 5.181486564444433, "Epigastric discomfort ": 2.1303969319188383, "Erectile dysfunction ": 2.7958751879965567, "Escherichia test positive ": 12.41131437835183, "Essential hypertension ": 15.538557868968844, "Eye operation ": 8.146558387597219, "Faecaloma ": 3.5741059461158784, "Failure to thrive ": 6.882051143515353, "Flatulence ": 2.4907596193313366, "Flour sensitivity ": 851.6940466569175, "Functional gastrointestinal disorder ": 2.341530866193384, "Gallbladder disorder ": 6.891627969314778, "Gallbladder enlargement ": 9.24346013856321, "Gallbladder operation ": 6.848911325784205, "Gastric ulcer ": 2.8011254259936016, "Gastric varices ": 22.944068092231003, "Gastritis ": 3.29039949417512, "Gastrointestinal disorder ": 2.757949605982369, "Gastrointestinal sounds abnormal ": 2.7459735770343414, "Gastrointestinal tube insertion ": 11.820283505952494, "Gastrointestinal wall thickening ": 16.068027751184317, "Gastrooesophageal reflux disease ": 5.887072291471896, "Gastrostomy ": 11.85000713548491, "Glaucoma ": 2.5399464586071274, "Glycosylated haemoglobin abnormal ": 24.983585131862306, "Glycosylated haemoglobin increased ": 5.542291628235651, "Goitre ": 3.2624858475316123, "Gout ": 3.858619869995816, "Granuloma ": 2.6033921909001174, "Haemangioma of bone ": 65.89959829726607, "Haemangioma of liver ": 12.137489227834823, "Haemoglobin increased ": 2.546846544237235, "Haemorrhoids ": 3.0484671735528712, "Helicobacter infection ": 2.155701288818075, "Hepatic cancer ": 2.089256003013672, "Hepatic cirrhosis ": 4.982316660693261, "Hepatic cyst ": 17.3324503987451, "Hepatic lesion ": 13.960536625289276, "Hepatic mass ": 4.922105956492443, "Hepatic steatosis ": 8.214726459942288, "Hepatitis acute ": 4.259912244242738, "Hepatomegaly ": 2.8402357754677285, "Hernia repair ": 14.619166618607922, "Hiatus hernia ": 6.072594581658309, "Hydronephrosis ": 2.8036604697081464, "Hyperchlorhydria ": 9.334841391426938, "Hypercholesterolaemia ": 6.74046109121503, "Hyperglycaemia ": 3.113214803658157, "Hyperkalaemia ": 2.207212455315605, "Hyperlactacidaemia ": 4.913308736228389, "Hyperlipidaemia ": 15.579623058804511, "Hypertension ": 2.066679366161157, "Hypoglycaemia ": 3.826717663323439, "Hypoglycaemic coma ": 2.089239798404699, "Hypomagnesaemia ": 3.160496023094699, "Hypovolaemia ": 2.607602963249857, "Hysterectomy ": 21.341633079720545, "Impaired gastric emptying ": 3.1634697441285624, "Inability to afford medication ": 8.276422176835913, "Inappropriate schedule of product administration ": 13.118898365690043, "Incorrect dose administered ": 4.012508839937042, "Inguinal hernia ": 8.934001137597342, "Insulin-requiring type 2 diabetes mellitus ": 60.31980507685837, "Intervertebral disc degeneration ": 3.022681062167986, "Intestinal metastasis ": 20.113043053081725, "Intestinal resection ": 7.432977143356597, "Intra-abdominal fluid collection ": 8.98328689544327, "Iron deficiency anaemia ": 4.587561763338549, "Jaundice cholestatic ": 2.251806406996531, "Knee operation ": 6.229673959581141, "Lactic acidosis ": 13.0537400613629, "Laparotomy ": 11.899209316879938, "Large intestinal polypectomy ": 45.908988500441744, "Large intestine polyp ": 8.457163747183063, "Left ventricular hypertrophy ": 2.7647809072996967, "Leukocytosis ": 2.988494567055332, "Lipase increased ": 17.04002262383921, "Lipoma ": 5.198422199596653, "Lumbar spinal stenosis ": 4.260525870162717, "Lung diffusion test decreased ": 29.43764126396596, "Lung opacity ": 4.107719595571671, "Lymphoma ": 2.301565927996368, "Malignant ascites ": 28.83186335285856, "Malignant neoplasm of ampulla of Vater ": 64.55445316299304, "Malnutrition ": 3.807384667278464, "Mastectomy ": 14.566003265736038, "Metabolic acidosis ": 4.441319586252592, "Metabolic disorder ": 2.137132623247167, "Metastases to abdominal cavity ": 18.26661707233712, "Metastases to adrenals ": 8.672430433070476, "Metastases to bone ": 2.1760633339579263, "Metastases to liver ": 19.86722797455172, "Metastases to lung ": 6.289501541293526, "Metastases to lymph nodes ": 16.911174490180073, "Metastases to peritoneum ": 32.591093776001884, "Metastases to spleen ": 41.19274318393758, "Metastasis ": 4.677292685727501, "Metastatic neoplasm ": 5.386877084256314, "Microalbuminuria ": 7.622660228825891, "Multiple allergies ": 3.9167183064023208, "Myocardial infarction ": 2.915181230998567, "Nephrolithiasis ": 5.330073768713016, "Neutrophilia ": 5.306298111242307, "Obstructive sleep apnoea syndrome ": 7.483540892896189, "Osteoarthritis ": 4.729625013115848, "Pancreatectomy ": 103.41019534321238, "Pancreatic carcinoma ": 51.440316858249815, "Pancreatic carcinoma metastatic ": 110.41004211417928, "Pancreatic carcinoma stage IV ": 48.44641928719288, "Pancreatic cyst ": 25.0953126842088, "Pancreatic disorder ": 5.690017729910943, "Pancreatic duct dilatation ": 71.3415470343592, "Pancreatic enzymes increased ": 9.064673798950643, "Pancreatic failure ": 6.701352793843782, "Pancreatic mass ": 23.845881555043864, "Pancreatic neoplasm ": 21.921872454985728, "Pancreatic neuroendocrine tumour ": 8.786327447522655, "Pancreatic pseudocyst ": 18.227238062616014, "Pancreatic stent placement ": 191.14148497573888, "Pancreaticoduodenectomy ": 170.10795683074954, "Pancreatitis ": 27.626295296434662, "Pancreatitis acute ": 17.099378456043898, "Pancreatitis chronic ": 34.558062817423206, "Pancreatitis necrotising ": 9.83296340018686, "Pemphigoid ": 6.37902902093416, "Peripheral arterial occlusive disease ": 2.347033230075813, "Pneumobilia ": 171.5832851999647, "Pneumonia klebsiella ": 7.136981755749122, "Polydipsia ": 3.5572962546358764, "Prescription drug used without a prescription ": 3.329489056769431, "Product availability issue ": 2.6374662888767424, "Product colour issue ": 5.026377358849203, "Product dispensing error ": 2.4208658886875427, "Product prescribing issue ": 5.861640684954498, "Product size issue ": 8.240783413111822, "Product taste abnormal ": 2.124366227912344, "Product use complaint ": 5.592577244810446, "Prostatitis ": 5.078699765440058, "Prostatomegaly ": 19.20455142904344, "Pulmonary granuloma ": 11.62897203542033, "Pulmonary mass ": 8.060156554004632, "Pulse abnormal ": 2.40640090005485, "Radiotherapy ": 29.39791720144687, "Regurgitation ": 3.118893004302316, "Renal cyst ": 18.660443414514063, "Renal disorder ": 2.9591753498991547, "Respiratory symptom ": 4.0501868784724815, "Rotator cuff repair ": 12.671764333352703, "Small intestinal obstruction ": 4.288615975899599, "Spinal operation ": 6.773576666071012, "Spinal osteoarthritis ": 10.247926472208215, "Splenectomy ": 38.50342442471683, "Splenic vein occlusion ": 148.60633613935835, "Splenic vein thrombosis ": 36.03663228986306, "Stent placement ": 4.660968495449603, "Surgery ": 4.001932360641263, "Suspected counterfeit product ": 5.342209508776272, "Thyroid cancer ": 5.522385934452648, "Thyroid mass ": 2.8285726511150115, "Thyroid operation ": 29.294801343146897, "Thyroidectomy ": 12.683965879919292, "Toe amputation ": 4.371103465973167, "Tonsillectomy ": 15.16844149877871, "Tumour invasion ": 72.69131295059448, "Type 2 diabetes mellitus ": 2.1289501421652712, "Umbilical hernia ": 8.967303554201997, "Uterine leiomyoma ": 2.486831060181707, "Varices oesophageal ": 4.941632104652662, "Vascular graft ": 6.453306694806062, "Vitamin B12 decreased ": 5.420318170587345, "Weight decreased ": 2.380902698971627, "Weight fluctuation ": 2.751495841908179, "Wrong technique in product usage process ": 6.167337163403306}
\ No newline at end of file
+{"Anaphylactoid reaction": 19.088555070127462, "Blood cholesterol increased": 5.851026675786622, "Blood creatine phosphokinase increased": 5.515483665600753, "Blood creatinine increased": 3.748518540921511, "Blood glucose abnormal": 20.3566449972741, "Blood glucose increased": 8.15665935778768, "Blood pressure decreased": 3.3394384321515225, "Blood urea increased": 27.438388995160302, "Cholestasis": 10.343487952075716, "Diabetes mellitus": 5.676870603236688, "Diabetes mellitus inadequate control": 7.786595303256626, "Drug interaction": 2.034121842989637, "Glycosylated haemoglobin increased": 31.151325040449557, "Hyperglycaemia": 5.706997139697428, "Hyperkalaemia": 4.728792443000772, "Hypoglycaemia": 19.69359836574509, "Renal failure": 2.082694021944888}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/603.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/603.json
index be83339b301..063219fb3f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/603.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/603.json
@@ -1 +1 @@
-{"Abdominal abscess ": 5.411829508548316, "Abdominal hernia ": 9.111805541926955, "Abdominal pain upper ": 2.0059930625830398, "Abdominal rigidity ": 4.007638307492361, "Abnormal loss of weight ": 3.907935796149604, "Acute kidney injury ": 2.410840691464608, "Adenocarcinoma pancreas ": 87.15553218523193, "Adrenal mass ": 31.49953015406459, "Adverse event ": 9.481294967558572, "Amylase increased ": 9.30897824846138, "Anaemia of chronic disease ": 39.20223787633837, "Angioplasty ": 7.077460816221555, "Anxiety disorder ": 2.6078026570130275, "Aortic aneurysm ": 6.340050655965332, "Aortic arteriosclerosis ": 36.81995971072208, "Appendicectomy ": 22.048758276953723, "Appendix disorder ": 20.47425259671117, "Arteriosclerosis ": 4.084677463673096, "Arteriosclerosis coronary artery ": 7.126013386007306, "Ascites ": 2.9548622956717066, "Atelectasis ": 11.915110828589231, "Atrioventricular block first degree ": 2.5940617338730334, "Barrett's oesophagus ": 3.899518240351196, "Benign prostatic hyperplasia ": 11.983323802685156, "Bile duct cancer ": 9.089296311098654, "Bile duct stenosis ": 45.911639727923706, "Bile duct stent insertion ": 207.5945946224801, "Bile duct stone ": 10.065711819156355, "Biliary dilatation ": 28.948313782289134, "Biliary obstruction ": 18.785304554755182, "Biliary tract disorder ": 10.085625649255206, "Biopsy liver ": 38.42672633533208, "Biopsy pancreas ": 230.84991083060143, "Bladder disorder ": 6.997635377179516, "Blood cholesterol abnormal ": 3.6104248793646816, "Blood glucose abnormal ": 7.728435781967854, "Blood glucose decreased ": 3.6641696805155335, "Blood glucose fluctuation ": 3.8786111760741258, "Blood glucose increased ": 4.498967441447852, "Blood loss anaemia ": 2.7426803045975863, "Blood potassium increased ": 2.031461032161722, "Blood pressure diastolic abnormal ": 6.157339770223707, "Blood pressure diastolic decreased ": 3.739223912193413, "Blood pressure systolic decreased ": 3.072645256243865, "Blood triglycerides increased ": 2.253327068895556, "Brain natriuretic peptide increased ": 3.127585634251673, "Cachexia ": 3.513754608801292, "Cardiac murmur ": 3.010871062150327, "Cardiac operation ": 3.0833737713961327, "Cardiac pacemaker insertion ": 6.972863985995172, "Cardiomegaly ": 2.2170918546334955, "Cardiovascular insufficiency ": 2.7951852559606523, "Carpal tunnel decompression ": 43.69653346331915, "Cataract ": 2.010877773722391, "Cataract operation ": 8.527728452256126, "Catheter placement ": 8.292377821636826, "Central venous catheterisation ": 5.937037726718078, "Cerebrovascular accident ": 2.068911264369683, "Cholangiocarcinoma ": 9.627784652677205, "Cholangitis ": 6.2382858210847045, "Cholecystectomy ": 19.566339869656584, "Cholecystitis ": 3.917782039632061, "Cholecystitis acute ": 2.938001639445291, "Cholecystitis chronic ": 14.426656911212511, "Cholelithiasis ": 10.612519155420008, "Chronic gastritis ": 5.026518104156921, "Chronic obstructive pulmonary disease ": 3.046042114918674, "Circumstance or information capable of leading to medication error ": 6.323790004703636, "Colectomy ": 9.436159042095078, "Colon cancer ": 2.961843118982559, "Colonoscopy ": 10.525422215393371, "Colorectal adenoma ": 6.694468535768031, "Complication associated with device ": 2.7312366393826726, "Constipation ": 3.25792348447324, "Coronary arterial stent insertion ": 7.073050111959407, "Coronary artery bypass ": 6.714038317963123, "Coronary artery disease ": 4.39884907423497, "Death ": 2.008295659075653, "Decubitus ulcer ": 3.0408725616524674, "Dehydration ": 2.44342497821472, "Dementia ": 2.2594358235708087, "Dermatitis bullous ": 2.0711471658524383, "Dermatitis exfoliative ": 3.1637372916046536, "Device occlusion ": 3.321174009284645, "Diabetes mellitus ": 3.305050453022337, "Diabetes mellitus inadequate control ": 19.180688467661472, "Diabetic complication ": 40.179247410170674, "Diabetic nephropathy ": 8.874988575258415, "Diabetic neuropathy ": 10.098974786103687, "Diabetic retinopathy ": 7.688628401269162, "Dialysis ": 5.127136322397493, "Diastolic dysfunction ": 3.791467854441077, "Disability assessment scale score increased ": 47.95484363882093, "Disease complication ": 4.790645945058527, "Diverticulum ": 8.774352220282179, "Diverticulum intestinal ": 11.855539869561465, "Ductal adenocarcinoma of pancreas ": 102.99031407032784, "Duodenal ulcer ": 3.7594226531965895, "Duodenitis ": 2.692060788775488, "Dyslipidaemia ": 4.769396955951773, "Dysphagia ": 3.409930239771515, "Emphysema ": 2.226606735218453, "Eosinophil count increased ": 2.296252776057526, "Essential hypertension ": 9.112397556056871, "Failure to thrive ": 3.8423422431972822, "Flatulence ": 2.048451849466444, "Fungal test positive ": 17.777012565447045, "Gallbladder disorder ": 6.886045928748315, "Gallbladder enlargement ": 9.142924728060771, "Gallbladder operation ": 7.394897326739481, "Gastric ulcer ": 2.668344078212165, "Gastritis ": 2.674295690074475, "Gastroenterostomy ": 156.3101028095204, "Gastrointestinal tube insertion ": 14.237684525825111, "Gastrooesophageal reflux disease ": 4.193857916288003, "Gastrostomy ": 13.692366248616723, "Gingivitis ": 2.160676047524135, "Glaucoma ": 3.5678032952166734, "Glycosylated haemoglobin abnormal ": 15.958974386412882, "Glycosylated haemoglobin decreased ": 15.163698231122646, "Glycosylated haemoglobin increased ": 6.906844466064206, "Goitre ": 2.034800700527514, "Gout ": 3.208445921147673, "Haemangioma of liver ": 10.909889206594755, "Haemorrhoid operation ": 55.17256324537502, "Haemorrhoids ": 2.105559600716193, "Hepatic cirrhosis ": 2.62291633798551, "Hepatic cyst ": 11.927521072229212, "Hepatic lesion ": 9.830982992202497, "Hepatic mass ": 10.065711819156355, "Hepatic steatosis ": 5.413213356394599, "Hernia repair ": 10.707654272441452, "Hiatus hernia ": 6.082942835515455, "Hunger ": 3.573810191574963, "Hypercholesterolaemia ": 5.513922783639032, "Hyperlipasaemia ": 16.563816658372744, "Hyperlipidaemia ": 11.766845045807733, "Hypertensive heart disease ": 5.2133195902605936, "Hypertriglyceridaemia ": 2.11199929218251, "Hypoglycaemia ": 7.818833163262205, "Hypoglycaemic coma ": 7.876784529663348, "Hypoglycaemic encephalopathy ": 18.55567434269789, "Hyporeflexia ": 3.015272438536037, "Hypovolaemia ": 3.4722612878907597, "Hysterectomy ": 16.49436088771977, "Ileus ": 4.968120112268087, "Impaired gastric emptying ": 3.028640280251992, "Inability to afford medication ": 13.834756738896036, "Increased tendency to bruise ": 2.21863202571045, "Inguinal hernia ": 5.109310757510031, "Insulin-requiring type 2 diabetes mellitus ": 66.15063661684395, "Insurance issue ": 3.355479327212588, "Interstitial lung disease ": 3.407923210034577, "Intervertebral disc degeneration ": 2.559528055596142, "Intestinal obstruction ": 3.330267841869171, "Iron deficiency anaemia ": 2.7318980392954737, "Jaundice cholestatic ": 4.142499603626009, "Ketoacidosis ": 2.084633540938085, "Knee arthroplasty ": 2.722173967592781, "Knee operation ": 5.599579872559818, "Lactic acidosis ": 2.829537625628609, "Laparotomy ": 26.279891388220648, "Large intestine polyp ": 4.495401065837074, "Leukocytosis ": 3.26894626282866, "Lipase abnormal ": 28.96956336952664, "Lipase increased ": 17.048021654068837, "Lipoma ": 5.697905834059018, "Lower respiratory tract congestion ": 13.978001519025815, "Malignant peritoneal neoplasm ": 17.584144466350097, "Malnutrition ": 6.5371979951144406, "Mammoplasty ": 32.371633368699, "Mastectomy ": 12.177316021787306, "Metastases to adrenals ": 13.121399701689672, "Metastases to bone ": 2.559705449641625, "Metastases to liver ": 17.51079759940971, "Metastases to lung ": 7.623409756973144, "Metastases to lymph nodes ": 13.19697488441654, "Metastases to peritoneum ": 12.638973958185373, "Metastases to spleen ": 14.738469939243368, "Metastasis ": 3.160345485280885, "Metastatic neoplasm ": 4.842037036549811, "Muscle tightness ": 2.252211803410609, "Neoplasm malignant ": 2.282813123309375, "Nephrolithiasis ": 4.021054637924353, "Normochromic normocytic anaemia ": 3.553495622279256, "Normocytic anaemia ": 3.7727303207559895, "Obstruction gastric ": 11.244190319169984, "Obstructive pancreatitis ": 12.98287556480673, "Obstructive sleep apnoea syndrome ": 6.104547756404069, "Oedematous pancreatitis ": 15.763101205581638, "Osteoarthritis ": 3.746527455364527, "Pancreatectomy ": 99.443323290227, "Pancreatic carcinoma ": 65.45542945970087, "Pancreatic carcinoma metastatic ": 93.2899845189841, "Pancreatic carcinoma stage IV ": 26.179956446116638, "Pancreatic cyst ": 25.0127214099448, "Pancreatic disorder ": 7.704838901039387, "Pancreatic duct dilatation ": 21.877513668252533, "Pancreatic enzymes increased ": 8.147849380561984, "Pancreatic mass ": 31.445443621359328, "Pancreatic neoplasm ": 11.325499520086856, "Pancreatic neuroendocrine tumour ": 7.117943810599132, "Pancreatic pseudocyst ": 11.084099614188649, "Pancreatic stent placement ": 101.2944267596451, "Pancreaticoduodenectomy ": 242.48014885587503, "Pancreatitis ": 36.443906758260574, "Pancreatitis acute ": 24.847722364374416, "Pancreatitis chronic ": 33.63753706259275, "Pancreatitis necrotising ": 18.4426117276304, "Pancreatitis relapsing ": 8.513367501894463, "Pancreatobiliary sphincterotomy ": 251.8054739786547, "Pemphigoid ": 39.925947295972136, "Peripheral vascular disorder ": 2.458773352660824, "Pneumobilia ": 67.64771204508088, "Polyp ": 3.0067486120070237, "Portal vein thrombosis ": 2.159127344941448, "Post procedural complication ": 2.063094705788182, "Product packaging quantity issue ": 7.323581151586458, "Product prescribing issue ": 2.526348914057953, "Product residue present ": 2.167479693854709, "Prostatomegaly ": 15.006842997796722, "Pulmonary mass ": 6.848373101185476, "Radiotherapy ": 30.19286576594793, "Renal cyst ": 16.592072601003256, "Renal disorder ": 2.030781637757403, "Renal mass ": 4.9056993141748535, "Rhabdomyolysis ": 2.0986702847123646, "Seronegative arthritis ": 34.66076063786128, "Sinus congestion ": 4.322411377141879, "Soft tissue injury ": 23.419770355256897, "Spinal operation ": 3.270677319000443, "Spinal osteoarthritis ": 8.610673112766573, "Splenectomy ": 24.422277086002293, "Splenic vein thrombosis ": 13.084852943744393, "Stent placement ": 8.122769349342567, "Surgery ": 3.776308005941461, "Throat cancer ": 3.5396585189141927, "Thyroid mass ": 4.105133675601592, "Toe amputation ": 3.50881997514175, "Tonsillectomy ": 40.74743326665609, "Type 2 diabetes mellitus ": 2.431855441583918, "Umbilical hernia ": 6.656263467274217, "Uterine leiomyoma ": 2.2353113238085918, "Vitamin B12 decreased ": 5.524205912729828, "Weight fluctuation ": 5.880919100784312, "Wrong technique in product usage process ": 4.329146970490279}
\ No newline at end of file
+{"Asthenia": 3.3676182627717512, "Off label use": 4.266100130784049}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/604.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/604.json
index b6191d181ae..1644a53e163 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/604.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/604.json
@@ -1 +1 @@
-{"Rash ": 14.513881431935465}
\ No newline at end of file
+{"Anaemia": 4.288756872469929, "Angina pectoris": 25.267803954709017, "Angina unstable": 41.09930766440105, "Blood potassium increased": 29.645190118139265, "Blood pressure decreased": 6.564848971669989, "Blood pressure systolic decreased": 83.14769727377978, "Bradycardia": 12.921589480449232, "Cardiac failure": 17.530223069988768, "Contusion": 12.236948448083806, "Dilated cardiomyopathy": 92.9027951113865, "Drug interaction": 6.116985375865525, "Dyspnoea exertional": 4.994070997371184, "ECG signs of myocardial ischaemia": 1124.7900986023074, "Ejection fraction decreased": 24.22491825993602, "Electrocardiogram QT prolonged": 14.944706497890229, "Fluid retention": 32.60789961809711, "Glomerular filtration rate decreased": 26.640445622249874, "Hypotension": 11.0629494381727, "Intentional self-injury": 17.022503347519358, "Mental disorder": 9.96525652703948, "Mitral valve incompetence": 35.82421899676855, "N-terminal prohormone brain natriuretic peptide increased": 80.44381262534556, "Oedema peripheral": 18.08607374374968, "Personality disorder": 98.99076893959575, "Presyncope": 19.74648643544044, "Psoriasis": 22.570009125551728, "Pulmonary oedema": 33.53716473875274, "Rales": 30.680095877063952, "Schizophrenia": 36.06121745877247, "Sinus arrest": 169.8045097608625, "Sinus bradycardia": 61.21954376347272, "Suicide attempt": 5.841694981373992, "Torsade de pointes": 14.452431858859548, "Treatment failure": 5.770739571380053, "Venous pressure jugular increased": 909.621439087268, "Ventricular arrhythmia": 45.93901715551617, "Ventricular dysfunction": 749.0346955618561, "Ventricular extrasystoles": 17.103482821467775, "Ventricular fibrillation": 13.381774976491432}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/605.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/605.json
index 12043926704..c752b9a6529 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/605.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/605.json
@@ -1 +1 @@
-{"Abnormal loss of weight ": 4.801740890471533, "Abscess ": 2.6944837279420786, "Abscess limb ": 4.780448596184982, "Acetonaemia ": 46.39168022478136, "Acidosis ": 11.579596267138612, "Acquired phimosis ": 70.54379367038923, "Acute kidney injury ": 3.0540044915988664, "Acute myocardial infarction ": 2.2614099076707594, "Adrenal insufficiency ": 2.497138464501347, "Altered state of consciousness ": 2.877542979619583, "Amputation ": 18.30594198260108, "Amylase increased ": 2.233571832938553, "Anal abscess ": 11.006052867288464, "Anal pruritus ": 2.769210884809375, "Anion gap ": 33.62096270061436, "Anion gap increased ": 5.178923155646612, "Anxiety disorder ": 4.3876998348601335, "Aortic valve replacement ": 6.087314031052674, "Bacterial test positive ": 3.353447651415428, "Bacteriuria ": 20.053690738585853, "Balanitis candida ": 271.809110623827, "Balanoposthitis ": 500.0130687873869, "Benign prostatic hyperplasia ": 2.6287490580911834, "Bladder cancer ": 3.225131579039912, "Bladder neoplasm ": 7.439349566077374, "Bladder pain ": 6.405618116516284, "Blindness ": 2.200560377425919, "Blood bicarbonate abnormal ": 33.38899182601525, "Blood bicarbonate decreased ": 3.3973972552316525, "Blood creatine increased ": 3.140052707638863, "Blood creatinine decreased ": 2.604213913054723, "Blood glucose abnormal ": 7.688193206084235, "Blood glucose decreased ": 2.371039581134648, "Blood glucose increased ": 3.4299067612660146, "Blood glucose normal ": 34.80169784181882, "Blood insulin decreased ": 30.41091522748447, "Blood ketone body ": 50.45762181837932, "Blood ketone body increased ": 109.44354931515493, "Blood ketone body present ": 29.154674865718928, "Blood pH abnormal ": 90.66832647287978, "Blood pH decreased ": 3.207776266907315, "Blood sodium increased ": 3.662972413178385, "Blood urine present ": 2.126059874790397, "Brain operation ": 4.097554443824843, "Brain stem infarction ": 2.801404525076701, "Breath odour ": 2.700179738509093, "COVID-19 pneumonia ": 2.6289045331425007, "Calculus urinary ": 4.979755256006145, "Candida infection ": 15.833458235358629, "Candida sepsis ": 7.745567236286045, "Cardiac failure ": 3.3275043759935667, "Cardiac operation ": 20.500149801187423, "Cardiac pacemaker insertion ": 3.2558753923421766, "Carotid artery stenosis ": 2.047691992522021, "Catheterisation cardiac ": 4.015816800054126, "Cellulitis of male external genital organ ": 101.29555790672087, "Cerebellar infarction ": 3.143025984803554, "Cerebral infarction ": 2.257530093549448, "Cerebrovascular accident ": 4.093612452643347, "Circumcision ": 106.40946322426382, "Coma acidotic ": 39.398991553231255, "Coronary arterial stent insertion ": 2.735760936899989, "Coronary artery bypass ": 7.473150337126444, "Creatinine renal clearance abnormal ": 28.773943708448492, "Culture urine positive ": 9.687369916474385, "Cystitis ": 10.212584493408531, "Cystitis haemorrhagic ": 2.496940674395949, "Cystitis noninfective ": 4.860290388643475, "Death ": 2.239697479614426, "Debridement ": 18.30986879328162, "Dehydration ": 7.893456052401319, "Dementia ": 4.728857955557423, "Diabetes mellitus inadequate control ": 2.068517325159802, "Diabetic coma ": 5.371521900967745, "Diabetic foot ": 13.556308451523613, "Diabetic foot infection ": 8.244784523169459, "Diabetic ketoacidosis ": 129.53236033856984, "Diabetic ketosis ": 35.219671564422946, "Diabetic metabolic decompensation ": 5.251119259200103, "Diet refusal ": 5.387306326675446, "Disease complication ": 4.560793083191063, "Dry mouth ": 2.362057715539907, "Dysuria ": 12.021156007378602, "Electrolyte imbalance ": 2.0183706471109675, "Emphysematous cystitis ": 58.75033885533983, "Emphysematous pyelonephritis ": 66.83936493014743, "Endotracheal intubation ": 2.088495870063936, "Epididymitis ": 7.486927317012153, "Escherichia infection ": 5.561746740969323, "Escherichia sepsis ": 4.673384982986748, "Escherichia urinary tract infection ": 6.069027123508414, "Euglycaemic diabetic ketoacidosis ": 539.4877288237964, "Extremity necrosis ": 10.071552464857172, "Eye operation ": 2.217988834485067, "Faeces hard ": 3.6322357387733226, "Failure to suspend medication ": 28.143386811326703, "Febrile infection ": 8.271446706783479, "Female reproductive tract disorder ": 30.957818849805463, "Flatulence ": 2.1335215158047047, "Fluid intake reduced ": 5.020399545658953, "Food craving ": 8.881953527636798, "Foot amputation ": 17.529359952492815, "Fournier's gangrene ": 527.484459202583, "Fungal balanitis ": 111.008593410883, "Fungal cystitis ": 95.33047787754155, "Fungal infection ": 37.47873351420503, "Fungal skin infection ": 3.617685638893763, "Gangrene ": 17.595760484441676, "Gastroenteritis ": 5.289713761698752, "Gastrointestinal infection ": 2.809379860524811, "Genital abscess ": 37.36415549023669, "Genital blister ": 35.10771013966773, "Genital burning sensation ": 55.69864914855376, "Genital candidiasis ": 159.89938037319976, "Genital discharge ": 23.075812549401217, "Genital discomfort ": 34.518564593873194, "Genital erythema ": 74.28538473195147, "Genital haemorrhage ": 2.225091119975347, "Genital herpes ": 2.227080194877809, "Genital infection ": 622.6050510271971, "Genital infection female ": 136.11923258133635, "Genital infection fungal ": 571.462430813072, "Genital infection male ": 318.45971060516763, "Genital pain ": 20.411634626234928, "Genital rash ": 23.55505908119773, "Genital swelling ": 36.65258157815828, "Genital tract inflammation ": 152.65840759011948, "Genital ulceration ": 12.781005190717526, "Genitourinary tract infection ": 330.9175402291273, "Glomerular filtration rate abnormal ": 8.889983646381813, "Glomerular filtration rate decreased ": 17.19735007123964, "Glomerular filtration rate increased ": 10.052622838322598, "Glucose urine ": 28.11855533488308, "Glucose urine present ": 45.55519758398425, "Glycosuria ": 25.42934990386668, "Glycosylated haemoglobin ": 26.479544845359836, "Glycosylated haemoglobin abnormal ": 35.01544088471152, "Glycosylated haemoglobin decreased ": 30.20169478597335, "Glycosylated haemoglobin increased ": 12.317116876336312, "Groin abscess ": 12.226608019564498, "Groin infection ": 18.224603545051057, "Haematocrit increased ": 51.86051337387845, "Haematuria ": 2.5647124553755, "Haemoglobin increased ": 12.60911246267694, "Heart valve operation ": 20.005793438378188, "Hunger ": 4.790496585940269, "Hyperglycaemia ": 2.4274590458928684, "Hyperglycaemic hyperosmolar nonketotic syndrome ": 27.519081179378546, "Hypernatraemia ": 8.935954615055323, "Hyperventilation ": 3.034740218011644, "Hypoglycaemia ": 2.4305338327709256, "Hypophagia ": 6.067664753534989, "Hypovolaemia ": 12.50705097525911, "Hypovolaemic shock ": 2.6678334283396348, "Incontinence ": 2.8550284174350056, "Increased appetite ": 2.000831254515014, "Inflammatory marker increased ": 2.244689008308591, "Insulin C-peptide decreased ": 30.53262809322468, "Intertrigo ": 10.219235685578544, "Ketoacidosis ": 208.16694170313176, "Ketonuria ": 68.26688936820682, "Ketosis ": 77.69950993819063, "Kidney infection ": 2.6110560738932667, "Klebsiella infection ": 2.844029121903007, "Knee operation ": 3.520265529217454, "Kussmaul respiration ": 18.06378038793672, "Lactic acidosis ": 4.446969200970843, "Lacunar infarction ": 3.910781484904638, "Latent autoimmune diabetes in adults ": 22.349252911197397, "Leg amputation ": 16.604985945736537, "Leukocyturia ": 11.060299917517954, "Lichen sclerosus ": 25.352570229184767, "Limb amputation ": 35.11456236835319, "Limb injury ": 2.391419129335128, "Lipase abnormal ": 14.42509155329727, "Lipase increased ": 2.6615758487331567, "Localised infection ": 3.171400740687021, "Low cardiac output syndrome ": 11.16674980490368, "Low density lipoprotein increased ": 2.551729823695472, "Metabolic acidosis ": 9.694514896800808, "Metabolic surgery ": 6.7273094002582825, "Microalbuminuria ": 5.327332361719206, "Micturition disorder ": 3.537439051433315, "Micturition frequency decreased ": 5.963639909434095, "Micturition urgency ": 12.70208558453816, "Mucosal dryness ": 2.0359780547263244, "Muscle atrophy ": 2.2793850735649914, "Myocardial infarction ": 3.609380148821226, "N-terminal prohormone brain natriuretic peptide increased ": 2.4423761711162544, "Near death experience ": 2.1414185224319247, "Necrosis ": 3.0995234714103725, "Necrotising fasciitis ": 75.1263403376006, "Necrotising oesophagitis ": 17.155465778462478, "Necrotising soft tissue infection ": 176.97175248692744, "Neoplasm malignant ": 3.296049819745635, "Nephrectomy ": 2.2052717099337267, "Nephritis ": 2.4302467603621647, "Nephrolithiasis ": 2.352933059557922, "Nocturia ": 13.61202647174065, "Oedema genital ": 8.814384670206216, "Oral fungal infection ": 6.742257935427442, "Orchidectomy ": 42.51197865267931, "Orchitis ": 19.368833094296768, "Osteomyelitis ": 4.389947286909426, "Pancreatic carcinoma ": 2.0858960275960685, "Pancreatitis ": 3.912976009527797, "Pancreatitis acute ": 2.162766703271535, "Pancreatitis necrotising ": 7.3300810337044915, "Pancreatitis relapsing ": 7.578264123282696, "Paraphimosis ": 104.49675120507555, "Pelvic abscess ": 8.888345771976178, "Pelvic inflammatory disease ": 8.329751717612467, "Penile burning sensation ": 59.22820325825489, "Penile dermatitis ": 80.93120106568271, "Penile discharge ": 39.36406010924392, "Penile discomfort ": 129.76614203802706, "Penile erythema ": 99.12479650292588, "Penile haemorrhage ": 6.312966461825265, "Penile infection ": 151.01235003664917, "Penile oedema ": 8.287050317828355, "Penile pain ": 11.245915468023275, "Penile swelling ": 27.867841269942637, "Penile ulceration ": 14.18390522947653, "Penis disorder ": 21.24784154423476, "Penis injury ": 23.740224185475597, "Perineal abscess ": 76.50574730028949, "Perineal infection ": 98.3797168180772, "Perineal pain ": 16.14107894428279, "Perineal swelling ": 384.6145035528135, "Peripheral artery occlusion ": 4.523240552508843, "Perirectal abscess ": 9.23377281705044, "Phimosis ": 259.70850349443134, "Physical assault ": 2.784938184573706, "Pollakiuria ": 25.511179269782065, "Polycythaemia ": 15.260105884660032, "Polydipsia ": 10.49512181479786, "Polyuria ": 21.097602727970973, "Post procedural complication ": 4.688576365666854, "Post procedural infection ": 2.5003885749015864, "Prerenal failure ": 6.8974527321722645, "Proctalgia ": 2.5489897241530137, "Prostatic abscess ": 47.39973294230192, "Prostatitis ": 24.711531922659635, "Prostatomegaly ": 5.080528071851669, "Protein urine ": 5.081013445716344, "Pruritus genital ": 111.44988062790392, "Pustule ": 2.03682098002026, "Pyelonephritis ": 24.80398482862736, "Pyelonephritis acute ": 17.50308089665486, "Red blood cell count increased ": 3.4860689827184874, "Renal abscess ": 15.970323319193897, "Renal function test abnormal ": 2.1647041880751776, "Renal pain ": 2.7928861628447725, "Renal tubular acidosis ": 2.0410090893963377, "Respiratory acidosis ": 4.167455347222631, "Scrotal abscess ": 136.35646859542538, "Scrotal infection ": 35.8951595431591, "Scrotal swelling ": 7.435794129940771, "Sepsis ": 4.846385217198344, "Septic shock ": 2.9758092744380487, "Shoulder arthroplasty ": 2.758386087465418, "Shoulder operation ": 2.47162077925628, "Skin abrasion ": 2.3003379658857126, "Skin fissures ": 5.790524039529504, "Skin odour abnormal ": 4.702889970042481, "Skin ulcer ": 3.098002610002665, "Starvation ": 7.057045069208138, "Starvation ketoacidosis ": 107.17586925621686, "Streptococcal infection ": 2.179778881654666, "Surgery ": 4.061396031008372, "Systemic candida ": 6.174864984212487, "Tachypnoea ": 3.2400753905934185, "Testicular abscess ": 98.2258618932756, "Thirst ": 15.869570830808316, "Toe amputation ": 36.553059754494726, "Troponin increased ": 4.947883235655883, "Urethral pain ": 8.244784523169459, "Urethritis ": 43.2396294930749, "Urethritis noninfective ": 24.27721596019476, "Urinary incontinence ": 3.713138474728701, "Urinary tract candidiasis ": 53.39968978486581, "Urinary tract discomfort ": 16.73473236229109, "Urinary tract infection ": 22.634416998893684, "Urinary tract infection bacterial ": 7.238293910795768, "Urinary tract infection fungal ": 48.17769250858611, "Urinary tract inflammation ": 12.089913089006986, "Urinary tract obstruction ": 4.068522557079353, "Urine abnormality ": 4.753768613097327, "Urine ketone body ": 132.541890987336, "Urine ketone body present ": 48.30644250438396, "Urine odour abnormal ": 10.206520759744848, "Urine output increased ": 25.12187277753988, "Urogenital disorder ": 69.00186692361179, "Urogenital infection bacterial ": 72.46077711316912, "Urogenital infection fungal ": 70.32229852377806, "Urosepsis ": 55.65477883895014, "Vaginal abscess ": 32.85275363247904, "Vaginal infection ": 36.94988496707706, "Vascular graft ": 11.26711554463185, "Ventricular asystole ": 16.606899204954473, "Vulval abscess ": 56.10683930616301, "Vulvitis ": 40.03715347361926, "Vulvovaginal burning sensation ": 15.014319815932826, "Vulvovaginal candidiasis ": 32.133074110426506, "Vulvovaginal discomfort ": 9.264102495907665, "Vulvovaginal dryness ": 5.678772535928389, "Vulvovaginal erythema ": 15.98956729932267, "Vulvovaginal inflammation ": 7.057045069208138, "Vulvovaginal mycotic infection ": 74.68813130779185, "Vulvovaginal pain ": 6.12018106651269, "Vulvovaginal pruritus ": 51.78722738505421, "Vulvovaginal swelling ": 21.93893996300957, "Vulvovaginitis ": 130.673196223988, "Weight decreased ": 5.682311977900619, "pH body fluid abnormal ": 93.02030402710128}
\ No newline at end of file
+{"Alanine aminotransferase increased": 15.199951144193657, "Dry eye": 77.82005651515487, "Insomnia": 9.916105429983393, "Rash": 6.04292756843595}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/606.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/606.json
index a85af198650..2ead5d03823 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/606.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/606.json
@@ -1 +1 @@
-{"Arrhythmia ": 5.971439602828725, "COVID-19 ": 3.054348564843507, "COVID-19 immunisation ": 14.321378354340272, "Chills ": 2.671156983359535, "Disturbance in attention ": 2.745208400414902, "Dizziness ": 2.6086307923131318, "Fatigue ": 2.16431446568056, "Feeling hot ": 4.440165533056033, "Influenza ": 8.72604600768434, "Injection site pain ": 3.707249111909928, "Injection site swelling ": 2.2167763259379547, "Interchange of vaccine products ": 9.584459182728647, "Limb discomfort ": 12.778438947000025, "Lymphadenopathy ": 2.252891895787213, "Myalgia ": 2.150954659312319, "SARS-CoV-2 test positive ": 26.0661657894208, "Suspected COVID-19 ": 10.87784496951629, "Tachycardia ": 3.4345710184958547, "Visual impairment ": 2.5679817323795118}
\ No newline at end of file
+{"Back pain": 2.2884820742434884, "Chronic fatigue syndrome": 54.86872942512818, "Erythema": 2.7293243742796083, "Hypoaesthesia": 3.143722088328015, "Migraine": 3.240425740413696}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/607.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/607.json
index 59f5fcf0902..4319dab8064 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/607.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/607.json
@@ -1 +1 @@
-{"Anterior chamber inflammation ": 172.84936584715766, "Blindness transient ": 63.62272212748079, "Corneal disorder ": 102.31673199909172, "Disease progression ": 19.634207040921208, "Drug ineffective for unapproved indication ": 12.579644328084632, "Dyschromatopsia ": 1303.6266700816795, "Eye pain ": 15.376187844445644, "Macular detachment ": 1078.3765261200688, "Macular hole ": 4742.731750220694, "Macular oedema ": 65.3759087378149, "Metamorphopsia ": 562.3379355361022, "Night blindness ": 897.1759333914919, "Ocular hyperaemia ": 13.713770737041854, "Optical coherence tomography abnormal ": 2182.0966030865507, "Photophobia ": 29.87340712707928, "Photopsia ": 406.7610016231488, "Pupillary reflex impaired ": 415.64417923908906, "Retinal detachment ": 309.59997281586044, "Retinal injury ": 1680.568291975413, "Retinal oedema ": 295.54086089338927, "Retinal tear ": 547.28167322381, "Retinogram abnormal ": 1513.6379296903715, "Rhegmatogenous retinal detachment ": 1503.9515480011232, "Subretinal fluid ": 2367.188877863163, "Therapy non-responder ": 19.68971586657152, "Vision blurred ": 19.493050935978797, "Visual acuity reduced ": 313.8552977799534, "Visual acuity reduced transiently ": 569.8555452218397, "Visual field defect ": 77.33559571568176, "Visual impairment ": 27.21344601221359, "Vitreous floaters ": 214.3381931016016}
\ No newline at end of file
+{"Actinic keratosis": 16.527244594502537, "Acute coronary syndrome": 2.2112747198431477, "Acute graft versus host disease": 2.9754000907972125, "Acute graft versus host disease in skin": 10.978294965445931, "Acute leukaemia": 31.327730510152374, "Acute lymphocytic leukaemia": 4.305886396688705, "Acute myeloid leukaemia": 29.867327429083023, "Acute myeloid leukaemia recurrent": 5.065169889454023, "Acute respiratory distress syndrome": 2.08540070567166, "Adenocarcinoma": 6.824853500780653, "Alanine aminotransferase abnormal": 4.095332633510832, "Alveolar proteinosis": 60.09298710381449, "Anaemia": 9.679463009899507, "Ascites": 4.26574108970212, "Aspergillus infection": 4.387693849812149, "Atypical mycobacterial infection": 13.560363430836237, "Autoimmune haemolytic anaemia": 3.058782412542934, "B-cell lymphoma": 4.579234646330851, "BK virus infection": 4.532120530282789, "Bacteraemia": 4.0762206434611095, "Basal cell carcinoma": 14.179998703937608, "Basophil count increased": 47.12477992299383, "Blast cell count increased": 170.55760727137766, "Blast cell crisis": 59.59556402375964, "Blast cells present": 77.26328339680032, "Blood bilirubin abnormal": 9.848901771880392, "Blood bilirubin increased": 2.063128447110906, "Blood creatinine abnormal": 5.2638655115579, "Blood disorder": 2.402887974818406, "Blood fibrinogen decreased": 8.738616695828075, "Blood lactate dehydrogenase increased": 12.778400709553582, "Blood potassium increased": 4.468510515495924, "Blood test abnormal": 2.087914004267117, "Blood uric acid increased": 2.0642300582126536, "Bone marrow disorder": 4.948869212899512, "Bone marrow failure": 3.018727194949302, "Bone marrow oedema": 9.920524249243169, "Bone pain": 2.473754060631246, "Bowen's disease": 62.5039694005586, "Bronchopulmonary aspergillosis": 3.076214448069253, "COVID-19 pneumonia": 2.0295579820418705, "Cachexia": 4.096549312134162, "Cardiac failure": 3.240843525628905, "Cardiac tamponade": 6.200842882617498, "Cerebral atrophy": 2.946719614177709, "Chronic graft versus host disease": 7.724895238447313, "Chronic lymphocytic leukaemia": 4.370996217257311, "Chronic myeloid leukaemia": 7.044115777540347, "Concomitant disease aggravated": 18.304296543207776, "Concomitant disease progression": 4.967769080767834, "Coronavirus infection": 7.735810487359698, "Creatinine renal clearance decreased": 2.8643656107263813, "Cystitis haemorrhagic": 2.962347958511822, "Cytokine storm": 25.902007661000315, "Cytomegalovirus infection": 4.119715122603307, "Cytomegalovirus infection reactivation": 3.0950537163822665, "Cytopenia": 12.694927732883158, "Death": 3.0060523729611046, "Diffuse large B-cell lymphoma": 10.125944857806116, "Diffuse large B-cell lymphoma stage IV": 67.63130154274111, "Disseminated tuberculosis": 15.505871196714654, "Dysphagia": 2.187173823096936, "Early satiety": 29.290741236796947, "Embolism": 2.123906130089238, "Epstein-Barr virus infection": 7.062068764725214, "Epstein-Barr virus infection reactivation": 4.17864784685497, "Erysipelas": 3.1119792930730514, "Escherichia sepsis": 7.085066108730372, "Escherichia urinary tract infection": 4.221589741136783, "Extramedullary haemopoiesis": 67.63130154274111, "Fasciitis": 43.12172376829006, "Fibrosis": 6.9906185844532684, "Full blood count abnormal": 4.174054840512145, "Full blood count decreased": 6.864549410321958, "Gamma-glutamyltransferase increased": 2.019385055193068, "Gastric ulcer": 2.6700429948396933, "Gastric varices haemorrhage": 26.3197505794818, "Gastrointestinal haemorrhage": 2.311847075427322, "General physical condition abnormal": 6.985947192479478, "General physical health deterioration": 3.1781983535141887, "Glomerular filtration rate decreased": 2.739039268546146, "Graft versus host disease": 8.898408166039426, "Graft versus host disease in gastrointestinal tract": 4.946653998405916, "Graft versus host disease in skin": 6.313849346398749, "Haematocrit abnormal": 17.43811155070475, "Haematocrit decreased": 10.45915323035157, "Haematocrit increased": 25.09826838520145, "Haematoma": 2.663874116361004, "Haematoma muscle": 2.372213621056585, "Haematotoxicity": 3.141661215605704, "Haemoglobin abnormal": 13.85744780869198, "Haemoglobin decreased": 15.291785113558053, "Haemoglobin increased": 10.487344168427972, "Haemolysis": 4.442414071943248, "Haemorrhage": 2.421289736360781, "Haemorrhage subcutaneous": 2.102382873307404, "Haemorrhagic diathesis": 2.2434705110878865, "Haemosiderosis": 88.30832907156403, "Haptoglobin decreased": 9.25034823936566, "Hepatitis B reactivation": 9.474871024021782, "Hepatomegaly": 6.643179267591862, "Hepatosplenomegaly": 11.061301136715556, "Hepatotoxicity": 2.060573320134922, "Herpes virus infection": 4.386958954300336, "Herpes zoster": 3.7766626563107946, "Hyperkeratosis": 2.053906392331211, "Hypertriglyceridaemia": 3.614439892547741, "Hyperuricaemia": 3.1068183740292614, "Hypogammaglobulinaemia": 3.3697185912527936, "Immunosuppression": 7.456102833237416, "Inappropriate schedule of 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2.6666490345885383, "Pneumonia fungal": 3.013734966686728, "Pneumonitis": 2.094469014569613, "Polycythaemia vera": 152.283281656998, "Portal hypertension": 5.501747821002779, "Portal vein thrombosis": 7.404538962492322, "Post herpetic neuralgia": 2.260410612159087, "Post procedural haemorrhage": 4.507086874985171, "Primary myelofibrosis": 400.3402440581692, "Product supply issue": 9.656479382561484, "Product use in unapproved indication": 5.160840334755516, "Progressive multifocal leukoencephalopathy": 4.522983552804912, "Pulmonary alveolar haemorrhage": 2.982980934284573, "Pulmonary arterial hypertension": 2.561714910035653, "Pulmonary hypertension": 5.021567313279503, "Pulmonary mass": 2.019084831100026, "Pulmonary tuberculosis": 9.13927380027386, "Pyoderma gangrenosum": 6.270867534750741, "Rectal cancer": 4.393145243569486, "Red blood cell count decreased": 6.556104982169239, "Red blood cell count increased": 21.943196076681197, "Red cell distribution width increased": 15.070755496723075, "Respiratory failure": 2.059108251892047, "Respiratory tract infection": 4.0697262845954, "Reticulocyte count increased": 14.126711586317986, "Second primary malignancy": 75.70693572238679, "Sepsis": 3.5552225486980062, "Septic shock": 3.5950263519213386, "Serum ferritin increased": 6.739270263579338, "Skin cancer": 12.998871154198088, "Skin haemorrhage": 2.960152434415458, "Skin lesion": 2.5701609077486656, "Skin papilloma": 4.191438405294417, "Skin ulcer": 2.114168601189512, "Spleen disorder": 82.29314769712573, "Splenic infarction": 22.64261785683987, "Splenic rupture": 48.16858513035238, "Splenomegaly": 98.28535254369685, "Squamous cell carcinoma": 38.2938281447495, "Squamous cell carcinoma of skin": 30.7952111940626, "Subdural haematoma": 2.194375579029814, "Sudden death": 2.0795804202266748, "Terminal state": 3.4810817178111835, "Therapeutic response decreased": 2.919101124685876, "Therapy non-responder": 3.950903210773504, "Thrombocytopenia": 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/608.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/608.json
index 96b7ca510c7..5e103013c94 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/608.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/608.json
@@ -1 +1 @@
-{"Muscle spasticity ": 480.8180825742653, "Overdose ": 28.387805474557503}
\ No newline at end of file
+{"COVID-19": 14.720106774047846, "COVID-19 immunisation": 30.132228411880945, "Drug ineffective": 4.808616469120532, "Interchange of vaccine products": 50.77818884962029, "SARS-CoV-2 test positive": 31.505736418313735, "Suspected COVID-19": 56.97341002569951, "Vaccination failure": 7.943152040062156}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/609.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/609.json
index bfd68ffcda3..0036aba168d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/609.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/609.json
@@ -1 +1 @@
-{"Accidental overdose ": 2.726638118135794, "Acute respiratory distress syndrome ": 2.651218122067656, "Altered state of consciousness ": 2.2973471479308376, "Anaemia ": 4.924874076678786, "Blood pressure decreased ": 3.452865592008124, "Bone marrow failure ": 6.176863200144685, "Bone pain ": 2.434318070513375, "Cellulitis ": 3.11699386572926, "Circulatory collapse ": 2.558965281842434, "Cystitis haemorrhagic ": 10.950967666655863, "Death ": 2.0580944392677543, "Decreased appetite ": 2.3674445990351285, "Dehydration ": 2.0130434384440963, "Diarrhoea ": 3.213987622470328, "Disease progression ": 13.068153446020697, "Disseminated intravascular coagulation ": 16.614566679473494, "Enteritis ": 6.867742130091692, "Enterocolitis ": 8.001727037253637, "Extravasation ": 22.20810187434947, "Febrile bone marrow aplasia ": 16.468389662816666, "Febrile neutropenia ": 85.26930555549139, "Gastrointestinal haemorrhage ": 2.072903768233016, "Haematotoxicity ": 10.568738710373212, "Haematuria ": 8.131462164610689, "Haemoglobin decreased ": 2.455683935165222, "Haemorrhage urinary tract ": 10.794935028984996, "Hormone-refractory prostate cancer ": 42.107361549761535, "Hydronephrosis ": 14.960358500526286, "Hypocalcaemia ": 3.3145491172610684, "Ileus ": 9.83694704904808, "Inappropriate antidiuretic hormone secretion ": 3.752455165499272, "Interstitial lung disease ": 6.140435186089639, "Intestinal perforation ": 7.166339622856966, "Ischaemic hepatitis ": 43.06972406313073, "Leukopenia ": 6.748448957639394, "Malignant neoplasm progression ": 2.209448956152972, "Metastases to bone ": 10.591024199035726, "Metastases to liver ": 3.2748000465265856, "Metastasis ": 10.476867917269118, "Mucosal inflammation ": 4.148808423897667, "Multiple organ dysfunction syndrome ": 4.186135230579333, "Myelosuppression ": 5.919793816580693, "Neuropathy peripheral ": 5.723231717497308, "Neurotoxicity ": 3.971893911862381, "Neutropenia ": 16.757678316307842, "Neutropenic infection ": 65.4639443293483, "Neutropenic sepsis ": 12.716553873488872, "Neutrophil count decreased ": 28.33011497075228, "Osteomyelitis ": 5.034794245238509, "Osteonecrosis of jaw ": 12.055093389380763, "Pancytopenia ": 5.253379999154351, "Performance status decreased ": 8.830975425837613, "Physical deconditioning ": 7.954452546646241, "Platelet count decreased ": 5.355441108827202, "Pleural effusion ": 2.191063587946617, "Pneumonia ": 2.827472358226308, "Pneumonia aspiration ": 2.280098098708521, "Pneumonia bacterial ": 16.179885360866663, "Product dispensing error ": 6.758245194668755, "Product storage error ": 3.4817700319491998, "Prostate cancer ": 8.027783234947151, "Prostate cancer metastatic ": 20.39173520269268, "Prostatic specific antigen increased ": 73.54458657594722, "Respiratory failure ": 2.4017474424620646, "Sepsis ": 9.260466592326614, "Septic shock ": 19.48714477896724, "Shock ": 4.774154670816518, "Taste disorder ": 2.8075736469532875, "Thrombocytopenia ": 4.455121140243636, "Tumour lysis syndrome ": 8.03179958758369, "White blood cell count decreased ": 5.9411736485686095, "White blood cell count increased ": 2.412244413109325}
\ No newline at end of file
+{"Abdominal abscess": 6.532095578303995, "Abdominal hernia": 4.2457376011247, "Abdominal lymphadenopathy": 10.351679757536989, "Abnormal loss of weight": 7.076779415434595, "Abscess drainage": 16.12786421658691, "Accident": 4.0770481398719145, "Acute kidney injury": 2.383977704440495, "Adenocarcinoma pancreas": 118.25915874205364, "Adrenal adenoma": 40.575826807618526, "Adrenal disorder": 7.760111313751481, "Adrenal mass": 51.44387742601574, "Adverse event": 7.309888809578701, "Amylase increased": 8.180354626332832, "Anaemia of chronic disease": 20.21212411019014, "Aneurysm": 2.5291117362540247, "Angioplasty": 11.776955572525369, "Ankle operation": 17.87016478392363, "Anuria": 2.3120838177425407, "Aortic aneurysm": 4.4939105479476575, "Aortic arteriosclerosis": 29.01245491009888, "Appendicectomy": 19.563454123946705, "Arterial disorder": 17.33624059352026, "Arterial occlusive disease": 3.055857161467437, "Arteriosclerosis": 5.584793707089239, "Arteriosclerosis coronary artery": 6.835829532451952, "Arthroscopy": 18.61263505834481, "Ascites": 2.008794100403612, "Atelectasis": 14.22263159992423, "Barrett's oesophagus": 4.857867188939815, "Benign prostatic hyperplasia": 13.330587295727218, "Bicytopenia": 3.872580174074093, "Bile duct stenosis": 31.07574086100994, "Bile duct stent insertion": 121.47132309481135, "Bile duct stone": 7.966826935465017, "Biliary dilatation": 22.494885087138755, "Biliary obstruction": 27.95187539466176, "Biopsy liver": 45.94382712475179, "Blood cholesterol abnormal": 7.8496324071896355, "Blood cholesterol increased": 2.7938478228699704, "Blood creatinine abnormal": 2.973802257692256, "Blood glucose abnormal": 12.311500053147006, "Blood glucose decreased": 3.414639783845977, "Blood glucose fluctuation": 5.736486694530003, "Blood glucose increased": 5.608414140921125, "Blood lactic acid": 52.0267677714317, "Blood lactic acid increased": 2.064220931679165, "Blood magnesium decreased": 3.2420097159105232, "Blood triglycerides abnormal": 13.022812045030404, "Blood triglycerides increased": 3.7737171749258094, "Bone lesion": 3.963706319567968, "Bundle branch block right": 2.052495986905681, "Calculus bladder": 11.369676687240514, "Cardiac murmur": 3.349362342927, "Cardiac operation": 6.2699708927515045, "Cardiac pacemaker insertion": 3.7211558858104175, "Cardiomegaly": 2.782908478496785, "Carpal tunnel decompression": 21.716820710747296, "Cataract operation": 11.270532916097508, "Catheter placement": 6.176997139851176, "Catheterisation cardiac": 3.061302273370511, "Central venous catheterisation": 6.005572355759472, "Cerebrovascular accident": 2.401843060616628, "Chemotherapy": 7.723254827986225, "Cholangiocarcinoma": 8.908871978941528, "Cholangitis": 7.838766309569979, "Cholecystectomy": 30.068292523083308, "Cholecystitis": 5.362200249388299, "Cholecystitis chronic": 24.61756925538015, "Cholelithiasis": 12.197014290731056, "Chronic gastritis": 8.12594858174351, "Circumstance or information capable of leading to 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18.43196795224644, "Ductal adenocarcinoma of pancreas": 70.27697403774542, "Duodenitis": 3.393304223382985, "Dyslipidaemia": 3.605410113075433, "Dysphagia": 6.257206372255195, "Dyspnoea at rest": 4.181503547542258, "Emphysema": 5.181003329842802, "Epigastric discomfort": 2.1301982611662367, "Erectile dysfunction": 2.7956144307246884, "Escherichia test positive": 12.410156959138003, "Essential hypertension": 15.537108715397943, "Eye operation": 8.14579865997022, "Faecaloma": 3.573772636553069, "Failure to thrive": 6.881409334048459, "Flatulence": 2.490324040676283, "Flour sensitivity": 851.614624534523, "Functional gastrointestinal disorder": 2.341312506092806, "Gallbladder disorder": 6.890985240644676, "Gallbladder enlargement": 9.242598129176717, "Gallbladder operation": 6.848272622590489, "Gastric ulcer": 2.7989938620289663, "Gastric varices": 22.94192843431816, "Gastritis": 3.2900926155803654, "Gastrointestinal disorder": 2.757605115554908, "Gastrointestinal sounds abnormal": 2.745717497949153, "Gastrointestinal tube insertion": 11.81918114799445, "Gastrointestinal wall thickening": 16.066529292699062, "Gastrooesophageal reflux disease": 5.886523132444875, "Gastrostomy": 11.848902034024205, "Glaucoma": 2.53970957903969, "Glycosylated haemoglobin abnormal": 24.98125515192253, "Glycosylated haemoglobin increased": 5.541774702632454, "Goitre": 3.262181597761555, "Gout": 3.858260003809165, "Granuloma": 2.6031494108573514, "Haemangioma of bone": 65.89345285284487, "Haemangioma of liver": 12.136357336474797, "Haemoglobin increased": 2.546609037372523, "Haemorrhoids": 3.048182863131012, "Helicobacter infection": 2.155500245708094, "Hepatic cancer": 2.0890611598548445, "Hepatic cirrhosis": 4.981851977366819, "Hepatic cyst": 17.33083394402624, "Hepatic lesion": 13.95923462273825, "Hepatic mass": 4.921646942681543, "Hepatic steatosis": 8.213960265882875, "Hepatitis acute": 4.259514955805113, "Hepatomegaly": 2.839970895133616, "Hernia repair": 14.617803265813818, "Hiatus hernia": 6.072028221539005, "Hydronephrosis": 2.803399007887481, "Hyperchlorhydria": 9.33397085750518, "Hypercholesterolaemia": 6.739832439922782, "Hyperglycaemia": 3.1129244147021717, "Hyperkalaemia": 2.2067011881135525, "Hyperlactacidaemia": 4.912850535698259, "Hyperlipidaemia": 15.578169888155136, "Hypertension": 2.066465157910894, "Hypoglycaemia": 3.8262306516846607, "Hypoglycaemic coma": 2.0890449551097547, "Hypomagnesaemia": 3.1602012772272867, "Hypovolaemia": 2.6073597858985464, "Hysterectomy": 21.339642665241865, "Impaired gastric emptying": 3.1631747258969667, "Inability to afford medication": 8.275650332508778, "Inappropriate schedule of product administration": 13.117674190133323, "Incorrect dose administered": 4.0121345719797, "Inguinal hernia": 8.933167948448475, "Insulin-requiring type 2 diabetes mellitus": 60.31417974484709, "Intervertebral disc degeneration": 3.0223991721408128, "Intestinal metastasis": 20.111167396698168, "Intestinal resection": 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"Metastases to adrenals": 8.67162167824525, "Metastases to bone": 2.175860393469856, "Metastases to liver": 19.865374686238628, "Metastases to lung": 6.288914943920665, "Metastases to lymph nodes": 16.90959720463442, "Metastases to peritoneum": 32.588054146787705, "Metastases to spleen": 41.18890164786829, "Metastasis": 4.676856486435232, "Metastatic neoplasm": 5.386374721631019, "Microalbuminuria": 7.62194937349781, "Multiple allergies": 3.916353047023783, "Myocardial infarction": 2.9149092855906016, "Nephrolithiasis": 5.328687474197184, "Neutrophilia": 5.305803263144907, "Obstructive sleep apnoea syndrome": 7.482842983019616, "Osteoarthritis": 4.7291838768633, "Pancreatectomy": 103.4005512457913, "Pancreatic carcinoma": 51.43551714075334, "Pancreatic carcinoma metastatic": 110.3997427617222, "Pancreatic carcinoma stage IV": 48.44190130591417, "Pancreatic cyst": 25.092972280027844, "Pancreatic disorder": 5.6894870901822685, "Pancreatic duct dilatation": 71.33489388512686, "Pancreatic enzymes increased": 9.063828452566163, "Pancreatic failure": 6.70072785338633, "Pancreatic mass": 23.843657714514, "Pancreatic neoplasm": 21.919828069078477, "Pancreatic neuroendocrine tumour": 8.785508068521194, "Pancreatic pseudocyst": 18.22553823376625, "Pancreatic stent placement": 191.12365993342445, "Pancreaticoduodenectomy": 170.09209210976098, "Pancreatitis": 27.623717050125368, "Pancreatitis acute": 17.097783197801025, "Pancreatitis chronic": 34.55483972598498, "Pancreatitis necrotising": 9.832046383073704, "Pemphigoid": 6.3784340712788685, "Peripheral arterial occlusive disease": 2.3468143560826324, "Pneumobilia": 171.56728376633947, "Pneumonia klebsiella": 7.13631619259466, "Polydipsia": 3.556964508173514, "Prescription drug used without a prescription": 3.3291785622625736, "Product availability issue": 2.6372203209680807, "Product colour issue": 5.025908616631675, "Product dispensing error": 2.420640120236335, "Product prescribing issue": 5.861094022116866, "Product size issue": 8.24001490252716, "Product taste abnormal": 2.1241681163521453, "Product use complaint": 5.592055682484848, "Prostatitis": 5.078226143822495, "Prostatomegaly": 19.202760364003048, "Pulmonary granuloma": 11.627887569794746, "Pulmonary mass": 8.059404802022135, "Pulse abnormal": 2.4061764889428754, "Radiotherapy": 29.395175491097792, "Regurgitation": 3.118602151108715, "Renal cyst": 18.658702955767613, "Renal disorder": 2.958460704621147, "Respiratory symptom": 4.049809171163564, "Rotator cuff repair": 12.670582614032336, "Small intestinal obstruction": 4.288216026052518, "Spinal operation": 6.77294495281802, "Spinal osteoarthritis": 10.246970710871578, "Splenectomy": 38.49983358569997, "Splenic vein occlusion": 148.5924779612779, "Splenic vein thrombosis": 36.033271581905616, "Stent placement": 4.66053381373437, "Surgery": 4.001559116299395, "Suspected counterfeit product": 5.341711307521712, "Thyroid cancer": 5.521870911840977, "Thyroid mass": 2.828308870888591, "Thyroid operation": 29.29206945646854, "Thyroidectomy": 12.682783019095847, "Toe amputation": 4.370695834824109, "Tonsillectomy": 15.167026945150411, "Tumour invasion": 72.68453382448082, "Type 2 diabetes mellitus": 2.1287515924101448, "Umbilical hernia": 8.96646727959023, "Uterine leiomyoma": 2.486599150075654, "Varices oesophageal": 4.941171264099967, "Vascular graft": 6.452704886085053, "Vitamin B12 decreased": 5.41981269751076, "Weight decreased": 2.380680591898834, "Weight fluctuation": 2.7512392486628525, "Wrong technique in product usage process": 6.166761866160029}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/61.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/61.json
index fec7088858d..22abec2eea5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/61.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/61.json
@@ -1 +1 @@
-{"Asthenia ": 5.698428346766091, "Nausea ": 4.799154589596066, "Neutropenia ": 25.443533426929605}
\ No newline at end of file
+{"Completed suicide": 153.44599510511185, "Toxicity to various agents": 84.87282914211947}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/610.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/610.json
index 1d2f6827a97..6b8a3a6a8ac 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/610.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/610.json
@@ -1 +1 @@
-{"Angioedema ": 79.35818143004069, "Death ": 13.770272579478965}
\ No newline at end of file
+{"Abdominal abscess": 5.411829508548316, "Abdominal hernia": 9.111805541926955, "Abdominal pain upper": 2.0059930625830398, "Abdominal rigidity": 4.007638307492361, "Abnormal loss of weight": 3.907935796149604, "Acute kidney injury": 2.410840691464608, "Adenocarcinoma pancreas": 87.15553218523193, "Adrenal mass": 31.49953015406459, "Adverse event": 9.481294967558572, "Amylase increased": 9.30897824846138, "Anaemia of chronic disease": 39.20223787633837, "Angioplasty": 7.077460816221555, "Anxiety disorder": 2.6078026570130275, "Aortic aneurysm": 6.340050655965332, "Aortic arteriosclerosis": 36.81995971072208, "Appendicectomy": 22.048758276953723, "Appendix disorder": 20.47425259671117, "Arteriosclerosis": 4.084677463673096, "Arteriosclerosis coronary artery": 7.126013386007306, "Ascites": 2.9548622956717066, "Atelectasis": 11.915110828589231, "Atrioventricular block first degree": 2.5940617338730334, "Barrett's oesophagus": 3.899518240351196, "Benign prostatic hyperplasia": 11.983323802685156, "Bile duct cancer": 9.089296311098654, "Bile duct stenosis": 45.911639727923706, "Bile duct stent insertion": 207.5945946224801, "Bile duct stone": 10.065711819156355, "Biliary dilatation": 28.948313782289134, "Biliary obstruction": 18.785304554755182, "Biliary tract disorder": 10.085625649255206, "Biopsy liver": 38.42672633533208, "Biopsy pancreas": 230.84991083060143, "Bladder disorder": 6.997635377179516, "Blood cholesterol abnormal": 3.6104248793646816, "Blood glucose abnormal": 7.728435781967854, "Blood glucose decreased": 3.6641696805155335, "Blood glucose fluctuation": 3.8786111760741258, "Blood glucose increased": 4.498967441447852, "Blood loss anaemia": 2.7426803045975863, "Blood potassium increased": 2.031461032161722, "Blood pressure diastolic abnormal": 6.157339770223707, "Blood pressure diastolic decreased": 3.739223912193413, "Blood pressure systolic decreased": 3.072645256243865, "Blood triglycerides increased": 2.253327068895556, "Brain natriuretic peptide increased": 3.127585634251673, "Cachexia": 3.513754608801292, "Cardiac murmur": 3.010871062150327, "Cardiac operation": 3.0833737713961327, "Cardiac pacemaker insertion": 6.972863985995172, "Cardiomegaly": 2.2170918546334955, "Cardiovascular insufficiency": 2.7951852559606523, "Carpal tunnel decompression": 43.69653346331915, "Cataract": 2.010877773722391, "Cataract operation": 8.527728452256126, "Catheter placement": 8.292377821636826, "Central venous catheterisation": 5.937037726718078, "Cerebrovascular accident": 2.068873835861853, "Cholangiocarcinoma": 9.627784652677205, "Cholangitis": 6.2382858210847045, "Cholecystectomy": 19.566339869656584, "Cholecystitis": 3.917782039632061, "Cholecystitis acute": 2.938001639445291, "Cholecystitis chronic": 14.426656911212511, "Cholelithiasis": 10.612519155420008, "Chronic gastritis": 5.026518104156921, "Chronic obstructive pulmonary disease": 3.046042114918674, "Circumstance or information capable of leading to medication error": 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3.791467854441077, "Disability assessment scale score increased": 47.95484363882093, "Disease complication": 4.790645945058527, "Diverticulum": 8.774352220282179, "Diverticulum intestinal": 11.855539869561465, "Ductal adenocarcinoma of pancreas": 102.99031407032784, "Duodenal ulcer": 3.7594226531965895, "Duodenitis": 2.692060788775488, "Dyslipidaemia": 4.769396955951773, "Dysphagia": 3.409930239771515, "Emphysema": 2.226606735218453, "Eosinophil count increased": 2.296252776057526, "Essential hypertension": 9.112397556056871, "Failure to thrive": 3.8423422431972822, "Flatulence": 2.048284719562479, "Fungal test positive": 17.777012565447045, "Gallbladder disorder": 6.886045928748315, "Gallbladder enlargement": 9.142924728060771, "Gallbladder operation": 7.394897326739481, "Gastric ulcer": 2.6665616954877653, "Gastritis": 2.674295690074475, "Gastroenterostomy": 156.3101028095204, "Gastrointestinal tube insertion": 14.237684525825111, "Gastrooesophageal reflux disease": 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7.818565274785982, "Hypoglycaemic coma": 7.876784529663348, "Hypoglycaemic encephalopathy": 18.55567434269789, "Hyporeflexia": 3.015272438536037, "Hypovolaemia": 3.4722612878907597, "Hysterectomy": 16.49436088771977, "Ileus": 4.968120112268087, "Impaired gastric emptying": 3.028640280251992, "Inability to afford medication": 13.834756738896036, "Increased tendency to bruise": 2.21863202571045, "Inguinal hernia": 5.109310757510031, "Insulin-requiring type 2 diabetes mellitus": 66.15063661684395, "Insurance issue": 3.355479327212588, "Interstitial lung disease": 3.407923210034577, "Intervertebral disc degeneration": 2.559528055596142, "Intestinal obstruction": 3.330267841869171, "Iron deficiency anaemia": 2.7309243044453506, "Jaundice cholestatic": 4.142499603626009, "Ketoacidosis": 2.084633540938085, "Knee arthroplasty": 2.722173967592781, "Knee operation": 5.599579872559818, "Lactic acidosis": 2.829537625628609, "Laparotomy": 26.279891388220648, "Large intestine polyp": 4.495401065837074, "Leukocytosis": 3.26894626282866, "Lipase abnormal": 28.96956336952664, "Lipase increased": 17.048021654068837, "Lipoma": 5.697905834059018, "Lower respiratory tract congestion": 13.978001519025815, "Malignant peritoneal neoplasm": 17.584144466350097, "Malnutrition": 6.5371979951144406, "Mammoplasty": 32.371633368699, "Mastectomy": 12.177316021787306, "Metastases to adrenals": 13.121399701689672, "Metastases to bone": 2.559705449641625, "Metastases to liver": 17.51079759940971, "Metastases to lung": 7.623409756973144, "Metastases to lymph nodes": 13.19697488441654, "Metastases to peritoneum": 12.638973958185373, "Metastases to spleen": 14.738469939243368, "Metastasis": 3.160345485280885, "Metastatic neoplasm": 4.842037036549811, "Muscle tightness": 2.252211803410609, "Neoplasm malignant": 2.282813123309375, "Nephrolithiasis": 4.020384811130277, "Normochromic normocytic anaemia": 3.553495622279256, "Normocytic anaemia": 3.7727303207559895, "Obstruction gastric": 11.244190319169984, "Obstructive pancreatitis": 12.98287556480673, "Obstructive sleep apnoea syndrome": 6.104547756404069, "Oedematous pancreatitis": 15.763101205581638, "Osteoarthritis": 3.746527455364527, "Pancreatectomy": 99.443323290227, "Pancreatic carcinoma": 65.45542945970087, "Pancreatic carcinoma metastatic": 93.2899845189841, "Pancreatic carcinoma stage IV": 26.179956446116638, "Pancreatic cyst": 25.0127214099448, "Pancreatic disorder": 7.704838901039387, "Pancreatic duct dilatation": 21.877513668252533, "Pancreatic enzymes increased": 8.147849380561984, "Pancreatic mass": 31.445443621359328, "Pancreatic neoplasm": 11.325499520086856, "Pancreatic neuroendocrine tumour": 7.117943810599132, "Pancreatic pseudocyst": 11.084099614188649, "Pancreatic stent placement": 101.2944267596451, "Pancreaticoduodenectomy": 242.48014885587503, "Pancreatitis": 36.443906758260574, "Pancreatitis acute": 24.847722364374416, "Pancreatitis chronic": 33.63753706259275, "Pancreatitis necrotising": 18.4426117276304, "Pancreatitis relapsing": 8.513367501894463, "Pancreatobiliary sphincterotomy": 251.8054739786547, "Pemphigoid": 39.925947295972136, "Peripheral vascular disorder": 2.458773352660824, "Pneumobilia": 67.64771204508088, "Polyp": 3.0067486120070237, "Portal vein thrombosis": 2.159127344941448, "Post procedural complication": 2.063094705788182, "Product packaging quantity issue": 7.323581151586458, "Product prescribing issue": 2.526348914057953, "Product residue present": 2.167479693854709, "Prostatomegaly": 15.006842997796722, "Pulmonary mass": 6.848373101185476, "Radiotherapy": 30.19286576594793, "Renal cyst": 16.592072601003256, "Renal disorder": 2.0304809583369448, "Renal mass": 4.9056993141748535, "Rhabdomyolysis": 2.0986702847123646, "Seronegative arthritis": 34.66076063786128, "Sinus congestion": 4.322411377141879, "Soft tissue injury": 23.419770355256897, "Spinal operation": 3.270677319000443, "Spinal osteoarthritis": 8.610673112766573, "Splenectomy": 24.422277086002293, "Splenic vein thrombosis": 13.084852943744393, "Stent placement": 8.122769349342567, "Surgery": 3.776308005941461, "Throat cancer": 3.5396585189141927, "Thyroid mass": 4.105133675601592, "Toe amputation": 3.50881997514175, "Tonsillectomy": 40.74743326665609, "Type 2 diabetes mellitus": 2.431855441583918, "Umbilical hernia": 6.656263467274217, "Uterine leiomyoma": 2.2353113238085918, "Vitamin B12 decreased": 5.524205912729828, "Weight fluctuation": 5.880919100784312, "Wrong technique in product usage process": 4.329146970490279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/611.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/611.json
index 1a7cab89e48..b6ef949d5df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/611.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/611.json
@@ -1 +1 @@
-{"Haemarthrosis ": 651.8662961820921, "Haemorrhage ": 67.11805663276392}
\ No newline at end of file
+{"Rash": 14.513682077389486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/612.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/612.json
index 6e3aaa21db2..1560a028dad 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/612.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/612.json
@@ -1 +1 @@
-{"Abdominal pain upper ": 3.1723417888235743, "Dysgeusia ": 14.826606885304164, "Dysphagia ": 8.012679659514697, "Inappropriate schedule of product administration ": 8.710665684569504, "Infection susceptibility increased ": 534.7258899892737, "Oesophageal candidiasis ": 321.3204320895036, "Off label use ": 4.678523612440918, "Oral candidiasis ": 97.95356823430126}
\ No newline at end of file
+{"Abnormal loss of weight": 4.800938010709016, "Abscess": 2.694033193211934, "Abscess limb": 4.779649287594931, "Acetonaemia": 46.38392341528336, "Acidosis": 11.577659973163684, "Acquired phimosis": 70.53199874589743, "Acute kidney injury": 3.0534937063116088, "Acute myocardial infarction": 2.2610317686903767, "Adrenal insufficiency": 2.496720920519916, "Altered state of consciousness": 2.87706179882228, "Amputation": 18.3028811611038, "Amylase increased": 2.233198366901149, "Anal abscess": 11.00421257309361, "Anal pruritus": 2.768747870739882, "Anion gap": 33.61534127907508, "Anion gap increased": 5.178057238962451, "Anxiety disorder": 4.386966190693309, "Aortic valve replacement": 6.086296231391503, "Bacterial test positive": 3.352886956335501, "Bacteriuria": 20.05033774379761, "Balanitis candida": 271.763662053063, "Balanoposthitis": 499.9294475045099, "Benign prostatic hyperplasia": 2.628309522925701, "Bladder cancer": 3.224592298861908, "Bladder neoplasm": 7.438105698422514, "Bladder pain": 6.404547069347236, "Blindness": 2.2001924088610147, "Blood bicarbonate abnormal": 33.38340919867413, "Blood bicarbonate decreased": 3.3968292062894, "Blood creatine increased": 3.139527680320352, "Blood creatinine decreased": 2.6037784865899867, "Blood glucose abnormal": 7.686907579985408, "Blood glucose decreased": 2.3706431022853023, "Blood glucose increased": 3.429333122070828, "Blood glucose normal": 34.79587899335255, "Blood insulin decreased": 30.405830531955708, "Blood ketone body": 50.44918500566067, "Blood ketone body increased": 109.42524896861867, "Blood ketone body present": 29.149800052582247, "Blood pH abnormal": 90.65316679319876, "Blood pH decreased": 3.2072399244159686, "Blood sodium increased": 3.662359960667823, "Blood urine present": 2.125704383476572, "Brain operation": 4.09686933093602, "Brain stem infarction": 2.8009361313534797, "Breath odour": 2.699728266493602, "COVID-19 pneumonia": 2.6284649607206942, "Calculus urinary": 4.978922631598486, "Candida infection": 15.830810436280908, "Candida sepsis": 7.744272172589071, "Cardiac failure": 3.3266408025342225, "Cardiac operation": 20.49672181622783, "Cardiac pacemaker insertion": 3.255330997879454, "Carotid artery stenosis": 2.0473496169051035, "Catheterisation cardiac": 4.015145346142033, "Cellulitis of male external genital organ": 101.27862142477788, "Cerebellar infarction": 3.142500468601705, "Cerebral infarction": 2.2571526020907817, "Cerebrovascular accident": 4.092853025220473, "Circumcision": 106.39167161189556, "Coma acidotic": 39.39240408212186, "Coronary arterial stent insertion": 2.735303515684218, "Coronary artery bypass": 7.471900758679796, "Creatinine renal clearance abnormal": 28.7691326415197, "Culture urine positive": 9.685750187682151, "Cystitis": 10.21087668267749, "Cystitis haemorrhagic": 2.4965231784904693, "Cystitis noninfective": 4.859477736873752, "Death": 2.239322869061374, "Debridement": 18.3068073580257, "Dehydration": 7.891703303862194, "Dementia": 4.728067211820578, "Diabetes mellitus inadequate control": 2.0681714406599188, "Diabetic coma": 5.370623760899034, "Diabetic foot": 13.554041733083196, "Diabetic foot infection": 8.243405999302322, "Diabetic ketoacidosis": 129.5106885467754, "Diabetic ketosis": 35.21378262328731, "Diabetic metabolic decompensation": 5.250241259986667, "Diet refusal": 5.386405571457816, "Disease complication": 4.560030511026739, "Dry mouth": 2.361662720436147, "Dysuria": 12.019145637311702, "Electrolyte imbalance": 2.018033165205887, "Emphysematous cystitis": 58.74051576045044, "Emphysematous pyelonephritis": 66.82818935348261, "Endotracheal intubation": 2.088146669052517, "Epididymitis": 7.485675490815025, "Escherichia infection": 5.560816785480192, "Escherichia sepsis": 4.672603585281306, "Escherichia urinary tract infection": 6.068012360036946, "Euglycaemic diabetic ketoacidosis": 539.3975028057515, "Extremity necrosis": 10.069868463699937, "Eye operation": 2.21761798694538, "Faeces hard": 3.631628422864468, "Failure to suspend medication": 28.13868120366488, "Febrile infection": 8.270063705979563, "Female reproductive tract disorder": 30.952642667395857, "Flatulence": 2.132990127855373, "Fluid intake reduced": 5.019560120220211, "Food craving": 8.880468419720158, "Foot amputation": 17.526428997293525, "Fournier's gangrene": 527.3962475357285, "Fungal balanitis": 110.99003288205569, "Fungal cystitis": 95.3145387929366, "Fungal infection": 37.46073701844024, "Fungal skin infection": 3.6170807592913263, "Gangrene": 17.592818231283392, "Gastroenteritis": 5.288829247667135, "Gastrointestinal infection": 2.808910124439997, "Genital abscess": 37.357908182237615, "Genital blister": 35.10184009340554, "Genital burning sensation": 55.68933577067613, "Genital candidiasis": 159.87264381542818, "Genital discharge": 23.071954291026465, "Genital discomfort": 34.512792909978344, "Genital erythema": 74.2729635297026, "Genital haemorrhage": 2.2247190831009784, "Genital herpes": 2.22670782542874, "Genital infection": 622.5009415789317, "Genital infection female": 136.09647261073528, "Genital infection fungal": 571.3668692659778, "Genital infection male": 318.4064627795978, "Genital pain": 20.408221633833275, "Genital rash": 23.55112053291146, "Genital swelling": 36.646453056991625, "Genital tract inflammation": 152.6328820168078, "Genital ulceration": 12.778868182044157, "Genitourinary tract infection": 330.8622086352936, "Glomerular filtration rate abnormal": 8.888497178933218, "Glomerular filtration rate decreased": 17.194474165429988, "Glomerular filtration rate increased": 10.05094202203462, "Glucose urine": 28.113853905460807, "Glucose urine present": 45.5475802846092, "Glycosuria": 25.42509783038011, "Glycosylated haemoglobin": 26.475117487031376, "Glycosylated haemoglobin abnormal": 35.0095859800841, "Glycosylated haemoglobin decreased": 30.196644897764397, "Glycosylated haemoglobin increased": 12.315057084845938, "Groin abscess": 12.224563718058734, "Groin infection": 18.22155639316904, "Haematocrit increased": 51.851841448044965, "Haematuria": 2.5642835864101925, "Haemoglobin increased": 12.607004109869685, "Heart valve operation": 20.00244847236067, "Hunger": 4.789695578264968, "Hyperglycaemia": 2.4270531158246302, "Hyperglycaemic hyperosmolar nonketotic syndrome": 27.514479810608723, "Hypernatraemia": 8.934460427879404, "Hyperventilation": 3.0342327881176594, "Hypoglycaemia": 2.4300446539057488, "Hypophagia": 6.066650143344289, "Hypovolaemia": 12.504959632028855, "Hypovolaemic shock": 2.6673873586681736, "Incontinence": 2.8545510399022267, "Increased appetite": 2.0004967034200782, "Inflammatory marker increased": 2.2443136919681925, "Insulin C-peptide decreased": 30.527523031532443, "Intertrigo": 10.217527028901626, "Ketoacidosis": 208.13212310760295, "Ketonuria": 68.25547436856795, "Ketosis": 77.6865174676479, "Kidney infection": 2.610619486933351, "Klebsiella infection": 2.843553595414779, "Knee operation": 3.5196769297492443, "Kussmaul respiration": 18.060760125618323, "Lactic acidosis": 4.446225560304851, "Lacunar infarction": 3.910127593967568, "Latent autoimmune diabetes in adults": 22.34551611401069, "Leg amputation": 16.602209425911745, "Leukocyturia": 11.058450616075968, "Lichen sclerosus": 25.348331164481177, "Limb amputation": 35.10869124705385, "Limb injury": 2.3910192634475296, "Lipase abnormal": 14.422679686767935, "Lipase increased": 2.661130812369028, "Localised infection": 3.170870456425434, "Low cardiac output syndrome": 11.164882724019574, "Low density lipoprotein increased": 2.5513031689946417, "Metabolic acidosis": 9.692893677509126, "Metabolic surgery": 6.726184593374055, "Microalbuminuria": 5.326441628154891, "Micturition disorder": 3.5368475804996047, "Micturition frequency decreased": 5.962642791561585, "Micturition urgency": 12.699961564650042, "Mucosal dryness": 2.035637637687995, "Muscle atrophy": 2.279003948361765, "Myocardial infarction": 3.6087764965702656, "N-terminal prohormone brain natriuretic peptide increased": 2.4419678053457843, "Near death experience": 2.141060471735376, "Necrosis": 3.099005219557937, "Necrotising fasciitis": 75.11377775754025, "Necrotising oesophagitis": 17.152597385978023, "Necrotising soft tissue infection": 176.94216277979285, "Neoplasm malignant": 3.2954986494541294, "Nephrectomy": 2.204902989355615, "Nephritis": 2.42984041896432, "Nephrolithiasis": 2.3521476366282235, "Nocturia": 13.609750309066753, "Oedema genital": 8.81291089974848, "Oral fungal infection": 6.741130600675347, "Orchidectomy": 42.50487069535817, "Orchitis": 19.36559452878269, "Osteomyelitis": 4.389213248561052, "Pancreatic carcinoma": 2.0855472431953337, "Pancreatitis": 3.912321633187283, "Pancreatitis acute": 2.162405055883138, "Pancreatitis necrotising": 7.328855406485429, "Pancreatitis relapsing": 7.576997027183109, "Paraphimosis": 104.4792793098068, "Pelvic abscess": 8.886859639932302, "Pelvic inflammatory disease": 8.328358987285599, "Penile burning sensation": 59.218300194654674, "Penile dermatitis": 80.91766949949618, "Penile discharge": 39.35747841742409, "Penile discomfort": 129.7444449577052, "Penile erythema": 99.10822215543, "Penile haemorrhage": 6.311910936753114, "Penile infection": 150.98710051426957, "Penile oedema": 8.285664727147765, "Penile pain": 11.244035096081188, "Penile swelling": 27.86318160148613, "Penile ulceration": 14.181533680909109, "Penis disorder": 21.24428873171295, "Penis injury": 23.736254779586226, "Perineal abscess": 76.49295529714693, "Perineal infection": 98.36326770400464, "Perineal pain": 16.138380132977797, "Perineal swelling": 384.5501977918016, "Peripheral artery occlusion": 4.522484260230947, "Perirectal abscess": 9.232228934998696, "Phimosis": 259.6650755421261, "Physical assault": 2.784472543182309, "Pollakiuria": 25.50691249979072, "Polycythaemia": 15.25755426953978, "Polydipsia": 10.493366910036327, "Polyuria": 21.094074618381025, "Post procedural complication": 4.687792406293442, "Post procedural infection": 2.499970506852168, "Prerenal failure": 6.896299462466815, "Proctalgia": 2.548563526524648, "Prostatic abscess": 47.39180771061071, "Prostatitis": 24.707399880674732, "Prostatomegaly": 5.0796785907936, "Protein urine": 5.0801639009876896, "Pruritus genital": 111.4312429896425, "Pustule": 2.0364804151905327, "Pyelonephritis": 24.79983701896609, "Pyelonephritis acute": 17.500154265704257, "Red blood cell count increased": 3.485486109505033, "Renal abscess": 15.967653044820963, "Renal function test abnormal": 2.1643422458353574, "Renal pain": 2.7924191633344835, "Renal tubular acidosis": 2.040667833458631, "Respiratory acidosis": 4.166758531801063, "Scrotal abscess": 136.33366938479966, "Scrotal infection": 35.88915790720246, "Scrotal swelling": 7.434550864430552, "Sepsis": 4.845574713731383, "Septic shock": 2.975311670589461, "Shoulder arthroplasty": 2.7579248864056467, "Shoulder operation": 2.471207525229015, "Skin abrasion": 2.299953343937678, "Skin fissures": 5.789555819032776, "Skin odour abnormal": 4.7021036330959385, "Skin ulcer": 3.097484587914696, "Starvation": 7.05586513463335, "Starvation ketoacidosis": 107.1579496295601, "Streptococcal infection": 2.1794144221908724, "Surgery": 4.060716903982898, "Systemic candida": 6.173832528950668, "Tachypnoea": 3.239067916915157, "Testicular abscess": 98.20943844744632, "Thirst": 15.86691686632605, "Toe amputation": 36.54694759618695, "Troponin increased": 4.947055899774461, "Urethral pain": 8.243405999302322, "Urethritis": 43.23239958666868, "Urethritis noninfective": 24.27315681471841, "Urinary incontinence": 3.712517579071693, "Urinary tract candidiasis": 53.39076118069734, "Urinary tract discomfort": 16.73193431627262, "Urinary tract infection": 22.63063053279506, "Urinary tract infection bacterial": 7.237083647321228, "Urinary tract infection fungal": 48.16963701929176, "Urinary tract inflammation": 12.087891655402556, "Urinary tract obstruction": 4.06784229522905, "Urine abnormality": 4.752973769098555, "Urine ketone body": 132.51972959503632, "Urine ketone body present": 48.29836515409082, "Urine odour abnormal": 10.204814145278556, "Urine output increased": 25.11767214787369, "Urogenital disorder": 68.99032974960721, "Urogenital infection bacterial": 72.4486617405501, "Urogenital infection fungal": 70.31054073902767, "Urosepsis": 55.64547171508388, "Vaginal abscess": 32.84726066367645, "Vaginal infection": 36.94370640947636, "Vascular graft": 11.2652316353317, "Ventricular asystole": 16.604122537259524, "Vulval abscess": 56.097458116975766, "Vulvitis": 40.03045915964419, "Vulvovaginal burning sensation": 15.011809303702227, "Vulvovaginal candidiasis": 32.12770103574482, "Vulvovaginal discomfort": 9.262553501584645, "Vulvovaginal dryness": 5.677823032157448, "Vulvovaginal erythema": 15.986893820931272, "Vulvovaginal inflammation": 7.05586513463335, "Vulvovaginal mycotic infection": 74.67564156750996, "Vulvovaginal pain": 6.119157749922886, "Vulvovaginal pruritus": 51.77856752872944, "Vulvovaginal swelling": 21.935271692573156, "Vulvovaginitis": 130.65134650861395, "Weight decreased": 5.681361517523005, "pH body fluid abnormal": 93.00475096510934}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/613.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/613.json
index 8ce936a4b32..8f27aa5187c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/613.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/613.json
@@ -1 +1 @@
-{"Disease progression ": 9.9664621922306, "Neuropathy peripheral ": 6.672731702963764, "Platelet count decreased ": 5.804759821534628, "Thrombocytopenia ": 4.3886846406466855}
\ No newline at end of file
+{"Arrhythmia": 5.677956653316686, "COVID-19": 3.123051378820356, "COVID-19 immunisation": 11.913113570655238, "Chills": 2.666046855320958, "Disturbance in attention": 2.6103857208255303, "Dizziness": 2.551039705232609, "Fatigue": 2.186700636207047, "Feeling hot": 4.221991613809632, "Influenza": 8.29678510128806, "Injection site pain": 3.524767500983491, "Injection site swelling": 2.1078862232316267, "Interchange of vaccine products": 9.953844508940737, "Limb discomfort": 12.35007605688596, "Lymphadenopathy": 2.1421484455819098, "Myalgia": 2.1012024369483875, "SARS-CoV-2 test positive": 24.785248983100423, "Suspected COVID-19": 10.343684200705374, "Tachycardia": 3.385730166135536, "Visual impairment": 2.4418260640925684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/614.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/614.json
index 6b9a187576e..08c85e19096 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/614.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/614.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.9832252135417776, "Abdominal pain ": 3.35798523299829, "Abdominal pain upper ": 3.1428976657812084, "Abnormal behaviour ": 2.1434377719629483, "Abortion induced ": 5.159001697457107, "Abortion spontaneous ": 5.801758721123785, "Acne ": 26.78271859512774, "Affect lability ": 2.6457417063892894, "Affective disorder ": 13.553637059290477, "Aggression ": 3.910124136844948, "Agitation ": 3.207171296121833, "Alanine aminotransferase increased ": 7.557386971503261, "Anger ": 7.849411130282721, "Anxiety ": 2.6593063058710427, "Apathy ": 3.220992855313835, "Aspartate aminotransferase increased ": 6.568300969711188, "Attention deficit hyperactivity disorder ": 10.769078587062983, "Autoimmune hepatitis ": 3.8506893861534826, "Behaviour disorder ": 17.599291055584022, "Bilirubin conjugated increased ": 7.5603166059571665, "Blood alkaline phosphatase increased ": 9.739479640647222, "Blood bilirubin increased ": 11.870065083431642, "Blood bilirubin unconjugated increased ": 25.482286294343577, "Blood creatine phosphokinase increased ": 6.204739312870132, "Body mass index increased ": 20.14572561615075, "Brain fog ": 4.232709832453297, "Breast enlargement ": 6.036611280745191, "Breast pain ": 2.49146576847176, "Bronchial secretion retention ": 21.185854291791117, "Butterfly rash ": 25.45847591435244, "Cataract ": 2.713989314188213, "Chalazion ": 247.67653199874184, "Cholecystitis acute ": 11.637961427310794, "Cholelithiasis ": 3.912263863510308, "Chromaturia ": 2.060491027700013, "Congenital absence of cranial vault ": 625.8334028246551, "Constipation ": 2.3679003248743653, "Cystic fibrosis ": 191.58883546167337, "Delusion ": 2.3581720156141506, "Depressed mood ": 8.44636609018098, "Depression ": 3.9648397358436087, "Dermatitis acneiform ": 13.767655817524668, "Dermatitis allergic ": 2.987810390436469, "Distal intestinal obstruction syndrome ": 742.5940736928019, "Disturbance in attention ": 3.035506800501325, "Drug eruption ": 4.402742838133394, "Drug-induced liver injury ": 4.285687497838473, "Dry eye ": 7.32673488039737, "Emotional disorder ": 3.638862564834876, "Eosinophilia ": 2.3575343863616145, "Epididymitis ": 26.201847336015497, "Exposure during pregnancy ": 5.294749480365308, "Flatulence ": 2.6677677561854525, "Forced expiratory volume decreased ": 40.29183501070369, "Gamma-glutamyltransferase increased ": 4.973081904227797, "Gestational diabetes ": 10.351004210338186, "Gilbert's syndrome ": 523.4614025466639, "Gynaecomastia ": 3.0776404721652773, "Haemoptysis ": 8.355507874314938, "Hemiplegic migraine ": 50.70549145749571, "Hepatic cirrhosis ": 3.7729948421462094, "Hepatic cytolysis ": 5.696746927502789, "Hepatic enzyme increased ": 3.790087792149658, "Hepatic failure ": 2.106941850169829, "Hepatocellular injury ": 5.460397552586802, "Hordeolum ": 63.25695761486933, "Hospitalisation ": 7.685288111599751, "Hyperbilirubinaemia ": 14.2892959181756, "Hypertransaminasaemia ": 14.810229418133726, "Idiopathic intracranial hypertension ": 20.23402519496648, "Illness ": 2.2729561959105795, "Impulsive behaviour ": 16.262998645444394, "Increased bronchial secretion ": 10.38566273672922, "Infection ": 3.036488738290396, "Infective pulmonary exacerbation of cystic fibrosis ": 108.21878536046133, "Initial insomnia ": 21.773676748792305, "Insomnia ": 2.5674365980347686, "Intensive care ": 24.113698814046117, "Intentional self-injury ": 4.271506978235504, "Intestinal obstruction ": 2.6648762699663635, "Intracranial pressure increased ": 17.41441473106559, "Irritability ": 4.920430549778263, "Listless ": 3.142555152760239, "Lithiasis ": 84.97749147897477, "Liver function test abnormal ": 2.5349645074168983, "Liver function test increased ": 9.759204938114392, "Liver transplant ": 14.72189004861564, "Lower respiratory tract infection ": 17.36542213956028, "Lung disorder ": 3.6287429421404673, "Mental disorder ": 7.672477799744856, "Middle insomnia ": 9.652365329911897, "Mood altered ": 7.659714375123392, "Mood swings ": 6.109029478646402, "Nasal congestion ": 2.061211464050231, "Nightmare ": 2.7359863225730057, "Ocular discomfort ": 2.4273492309064038, "Orchitis ": 32.56816283301198, "Panic attack ": 2.81115648154628, "Papilloedema ": 19.145455473209356, "Personality change ": 4.700152995709196, "Pneumothorax ": 2.9048045081518765, "Poor quality sleep ": 3.436273604294017, "Portal hypertension ": 10.467773024288835, "Productive cough ": 15.529316403851697, "Pseudomonas infection ": 10.942568534312135, "Psychomotor hyperactivity ": 5.676928787233578, "Pulmonary function test decreased ": 28.03284423729225, "Pulmonary haemorrhage ": 7.2790766469358115, "Pulmonary pain ": 3.699865485357378, "Rash ": 2.970779110526958, "Rash erythematous ": 2.322508195490274, "Rash macular ": 3.2696538704262386, "Rash maculo-papular ": 5.524423925826596, "Rash pruritic ": 5.957822623776094, "Restlessness ": 2.037527893989658, "SARS-CoV-2 test positive ": 3.046375783943583, "Secretion discharge ": 6.9055992630144605, "Self-destructive behaviour ": 6.291342630540044, "Sleep disorder ": 6.284016319867672, "Sleep terror ": 16.42130161293499, "Sputum increased ": 63.803963797173466, "Steatorrhoea ": 66.80992277013985, "Suicidal ideation ": 2.8808845881947107, "Surgery ": 8.297899944759154, "Sweat test abnormal ": 755.9659322881746, "Testicular pain ": 22.41079218541327, "Tic ": 6.391404483687637, "Transaminases increased ": 10.850575786748836, "Transplant ": 29.988371196912222, "Vaginal discharge ": 2.264826345714297, "Viral infection ": 6.68377693789446, "Vitamin A increased ": 1523.9929785452157}
\ No newline at end of file
+{"Anterior chamber inflammation": 172.84936584715766, "Blindness transient": 63.62272212748079, "Corneal disorder": 102.31673199909172, "Disease progression": 19.634207040921208, "Drug ineffective for unapproved indication": 12.579644328084632, "Dyschromatopsia": 1303.6266700816795, "Eye pain": 15.376187844445644, "Macular detachment": 1078.3765261200688, "Macular hole": 4742.731750220694, "Macular oedema": 65.3759087378149, "Metamorphopsia": 562.3379355361022, "Night blindness": 897.1759333914919, "Ocular hyperaemia": 13.713770737041854, "Optical coherence tomography abnormal": 2182.0966030865507, "Photophobia": 29.870651979182032, "Photopsia": 406.7610016231488, "Pupillary reflex impaired": 415.64417923908906, "Retinal detachment": 309.59997281586044, "Retinal injury": 1680.568291975413, "Retinal oedema": 295.54086089338927, "Retinal tear": 547.28167322381, "Retinogram abnormal": 1513.6379296903715, "Rhegmatogenous retinal detachment": 1503.9515480011232, "Subretinal fluid": 2367.188877863163, "Therapy non-responder": 19.687993823726767, "Vision blurred": 19.493050935978797, "Visual acuity reduced": 313.8552977799534, "Visual acuity reduced transiently": 569.8555452218397, "Visual field defect": 77.33559571568176, "Visual impairment": 27.21344601221359, "Vitreous floaters": 214.3381931016016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/615.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/615.json
index b0f6d05b24d..6058cc5a8ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/615.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/615.json
@@ -1 +1 @@
-{"Abdominal hernia ": 5.408047478773876, "Abdominal tenderness ": 2.4648132091433794, "Abortion induced ": 12.279363035061952, "Abortion spontaneous ": 3.588582679833056, "Accidental overdose ": 2.016891151012745, "Acquired immunodeficiency syndrome ": 61.78360871536852, "Acrochordon ": 29.81291877964241, "Acute hepatic failure ": 3.1796066045665903, "Acute kidney injury ": 3.418761654975793, "Acute respiratory distress syndrome ": 5.862990186903089, "Adrenal insufficiency ": 3.815296748426225, "Adrenal suppression ": 10.21073323652273, "Alanine aminotransferase increased ": 2.0762488656180764, "Amylase increased ": 3.4756196684254057, "Anaemia ": 2.529848075828755, "Anaemia macrocytic ": 5.241832436686096, "Anogenital warts ": 55.25217805853367, "Anti-neutrophil cytoplasmic antibody positive vasculitis ": 16.356085092997674, "Antiviral drug level above therapeutic ": 303.6379803569546, "Arterial spasm ": 60.86330433956943, "Aspartate aminotransferase increased ": 2.118117043770688, "Aspiration bursa ": 1041.7043582125457, "Atrial septal defect ": 3.098005466921921, "Atrioventricular block ": 2.532749644549217, "Atrioventricular block complete ": 3.344064698185585, "Atrioventricular block first degree ": 3.889540288050576, "Autoimmune thyroiditis ": 5.556267392289751, "Behaviour disorder ": 2.563454208762449, "Benign prostatic hyperplasia ": 11.598803509844087, "Bilirubin conjugated increased ": 7.594087121217274, "Biopsy liver abnormal ": 32.78124675914216, "Blood HIV RNA increased ": 24.328441077293157, "Blood bilirubin increased ": 3.004924032435068, "Blood bilirubin unconjugated increased ": 16.717448987301786, "Blood creatinine abnormal ": 4.242224377420899, "Blood creatinine increased ": 2.280655492006956, "Blood lactate dehydrogenase increased ": 2.698795790010943, "Blood lactic acid increased ": 6.3248633928658045, "Blood triglycerides increased ": 12.050641833005118, "Bone demineralisation ": 3.9853695661094974, "Bone density decreased ": 5.301092496891122, "Bone loss ": 8.44481672202837, "Bone marrow failure ": 2.829445608407649, "Bone metabolism disorder ": 92.4327376636144, "Bradycardia ": 2.106316986404012, "Breath odour ": 7.010672306491818, "CD4 lymphocytes decreased ": 37.35254727877938, "COVID-19 treatment ": 465.56232101939474, "Cachexia ": 14.552465989513538, "Caesarean section ": 8.449346454504589, "Cardiac murmur ": 2.420492024510065, "Carotid artery stenosis ": 5.318978865928611, "Cerebellar syndrome ": 8.909395589077814, "Cerebral toxoplasmosis ": 23.632172651830643, "Cholestasis ": 6.010480822929652, "Chronic kidney disease ": 3.676660290626268, "Coarctation of the aorta ": 12.568484177670154, "Congenital anomaly ": 3.557491399146695, "Congenital aplasia ": 10.600956493436724, "Congenital hearing disorder ": 83.80333773959204, "Coronavirus infection ": 3.782319001564674, "Cortisol decreased ": 11.619649308298085, "Cryptorchism ": 10.591188329042431, "Cushing's syndrome ": 47.39549579301694, "Cushingoid ": 15.805901140143929, "Cyst ": 2.8369020850759097, "Cytomegalovirus chorioretinitis ": 7.165709482072099, "Cytomegalovirus infection ": 2.1118791651262017, "Developmental delay ": 4.219132989062504, "Diarrhoea ": 3.267668496501212, "Drug interaction ": 4.375190700612314, "Drug level changed ": 22.53118209201996, "Drug level decreased ": 2.4322984104551035, "Drug level increased ": 7.890271109023095, "Drug-induced liver injury ": 2.1512206564674687, "Dyslipidaemia ": 22.44941901848393, "Dysmorphism ": 2.923570590488551, "Economic problem ": 2.5094102097261235, "Electrocardiogram QT prolonged ": 6.959521425242634, "Electrocardiogram abnormal ": 2.806224200059849, "Electrolyte imbalance ": 2.969413682696282, "Encephalitis ": 2.452420451529373, "Endotracheal intubation ": 15.18056442012873, "Ergot poisoning ": 43.67966280308951, "Erythema nodosum ": 3.4245530662800414, "Eyelid ptosis ": 2.81837382571774, "Fanconi syndrome ": 56.59854860520182, "Fanconi syndrome acquired ": 11.446679407010723, "Fat redistribution ": 46.16965426786876, "Foetal death ": 5.343209436172897, "Foetal distress syndrome ": 6.998429733696829, "Foetal exposure during pregnancy ": 4.508901934644183, "Foetal growth restriction ": 4.395648781219613, "Foot fracture ": 2.9285158116091585, "Fracture ": 11.153506224471576, "Gamma-glutamyltransferase increased ": 2.515223167328671, "Gastritis ": 2.915328306687168, "Gastrointestinal disorder ": 2.577004540108397, "Glomerular filtration rate abnormal ": 6.550554786667801, "Glycosuria ": 7.481035001476095, "HIV infection ": 14.630431897388243, "HIV test positive ": 26.43780773610682, "Hepatic cancer ": 4.897371608997988, "Hepatic cytolysis ": 12.533421129606683, "Hepatic failure ": 2.8120481449211856, "Hepatic lesion ": 4.611709795982127, "Hepatitis ": 4.738105560542512, "Hepatitis acute ": 2.9289878970262007, "Hepatocellular injury ": 7.009012108048632, "Hepatomegaly ": 4.778726089406887, "Hepatosplenomegaly ": 4.139265663746004, "Hepatotoxicity ": 3.965942206987117, "Herpes virus infection ": 2.8073357954289966, "Hip fracture ": 3.121032832714402, "Hip surgery ": 4.531528109753318, "Hodgkin's disease ": 5.964419480244043, "Humerus fracture ": 11.830859618891978, "Hydrocephalus ": 3.872752674717096, "Hyperbilirubinaemia ": 11.241384669984058, "Hypercholesterolaemia ": 4.609767340027047, "Hyperlactacidaemia ": 18.560511792706837, "Hyperlipasaemia ": 15.731338313306871, "Hyperlipidaemia ": 4.686706307940899, "Hypertransaminasaemia ": 11.52045380916123, "Hypertriglyceridaemia ": 57.19613741529389, "Hypophagia ": 2.3749194230790414, "Hypophosphataemia ": 12.548102452650392, "Hypospadias ": 5.774242417544768, "Ileus paralytic ": 5.4228912935829765, "Immune reconstitution inflammatory syndrome ": 24.574738601049937, "Immunosuppressant drug level increased ": 13.96089286266653, "Incoherent ": 2.9995746638831653, "Jaundice ": 4.996178392122745, "Kaposi's sarcoma ": 16.64967424057314, "Kidney infection ": 5.590742591530742, "Kidney malformation ": 27.203422015822767, "Lactic acidosis ": 5.48629938283975, "Lipase increased ": 6.006202476849299, "Lipids increased ": 14.103983110461328, "Lipoatrophy ": 10.605008895367536, "Lipodystrophy acquired ": 20.463836895459032, "Live birth ": 7.092025400495164, "Liver function test abnormal ": 4.857936210709581, "Long QT syndrome ": 25.918491042939127, "Lymphoma ": 2.7992081760117733, "Lymphopenia ": 2.693984630671448, "Magnetic resonance imaging head abnormal ": 6.922696514695927, "Mechanical ventilation ": 15.43189770366376, "Meningitis cryptococcal ": 16.869321207753014, "Mitochondrial toxicity ": 16.355617336897613, "Multiple fractures ": 6.505589673364803, "Mycobacterium avium complex infection ": 7.528109052886492, "Nephrogenic diabetes insipidus ": 5.5308123837868814, "Nephropathy toxic ": 2.819130014787876, "Non-Hodgkin's lymphoma ": 3.196539742375133, "Normal newborn ": 3.082574860960762, "Nystagmus ": 2.1669977229298123, "Oesophageal atresia ": 33.00140241118983, "Oesophageal candidiasis ": 12.206937488055887, "Off label use ": 3.2602526748048724, "Oliguria ": 4.35374220437765, "Oral candidiasis ": 2.0491084178176253, "Organising pneumonia ": 3.4972754920815365, "Osteogenesis imperfecta ": 42.532756143564455, "Osteomalacia ": 4.4159530769092905, "Osteonecrosis ": 10.440469673963497, "Osteopenia ": 3.622578632293048, "Osteoporosis ": 6.879071022701591, "Pancreatitis ": 2.961680146897196, "Pancreatitis acute ": 3.4857999729663933, "Patella fracture ": 12.765750670362692, "Patent ductus arteriosus ": 4.919850697279562, "Peripheral ischaemia ": 4.92907737695531, "Peripheral sensorimotor neuropathy ": 10.272232817797898, "Personality disorder ": 6.244526468310814, "Pneumocystis jirovecii pneumonia ": 4.44212250808757, "Portal hypertension ": 4.433366126230136, "Pregnancy on contraceptive ": 22.731393287479904, "Premature baby ": 3.619797209126382, "Premature delivery ": 2.7104037076259693, "Premature labour ": 4.942252506738883, "Premature rupture of membranes ": 14.324702326996333, "Progressive multifocal leukoencephalopathy ": 11.558470089264862, "Protein total abnormal ": 7.672892858527975, "Proteinuria ": 2.6129317627185995, "Psychiatric symptom ": 3.2095535039873906, "Pulmonary tuberculosis ": 9.92958838410139, "Pulse absent ": 3.3577334634366665, "Pyelocaliectasis ": 27.603564096551345, "Renal disorder ": 2.422920600686157, "Renal dysplasia ": 46.50101151080655, "Renal failure ": 4.21656798986675, "Renal injury ": 8.145178035217796, "Renal tubular acidosis ": 15.663948247430408, "Renal tubular disorder ": 10.351320836055802, "Renal tubular necrosis ": 8.266864373956615, "Respiratory failure ": 2.354160410974297, "Respiratory rate increased ": 2.125209410227226, "Rhabdomyolysis ": 2.731748008480644, "Rhinitis allergic ": 2.2084972018753803, "Shoulder fracture ": 3.127279308569782, "Sinus bradycardia ": 6.114027334292162, "Skeletal injury ": 8.029968308061274, "Skin striae ": 11.070606604495058, "Small for dates baby ": 7.863935946196288, "Stillbirth ": 20.99932324733667, "Strabismus ": 5.1745785556216495, "Sudden death ": 2.165854177618717, "Therapeutic response unexpected ": 4.643350187378398, "Tooth disorder ": 2.513116110078061, "Tooth fracture ": 3.0837466258826325, "Tooth loss ": 4.52737054330724, "Toxic skin eruption ": 2.725761162499714, "Toxoplasmosis ": 16.600565210882344, "Transaminases increased ": 4.441487837264154, "Tricuspid valve incompetence ": 3.030593318431765, "Trisomy 21 ": 15.563961701253438, "Tuberculosis ": 4.129926300606878, "Unevaluable event ": 2.5818743854755954, "Upper limb fracture ": 4.229969470959063, "Urinary tract obstruction ": 8.909395589077814, "Varices oesophageal ": 12.152385530181544, "Ventricular septal defect ": 5.871981359906349, "Viral load increased ": 25.4041516903568, "Virologic failure ": 4.068283849294812, "Walking disability ": 6.187372991036302}
\ No newline at end of file
+{"Muscle spasticity": 480.6933859836327, "Overdose": 28.387805474557503}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/616.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/616.json
index cacf4209b65..0870ef8013b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/616.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/616.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.9975189812819782, "Acne ": 4.158813117213652, "Alanine aminotransferase increased ": 3.2811975552251385, "Aspartate aminotransferase increased ": 2.643279813657028, "Chest discomfort ": 2.281922482141893, "Cough ": 2.7525069827682493, "Cystic fibrosis ": 602.1557235459907, "Cystic fibrosis respiratory infection suppression ": 1163.827272484795, "Exposure during pregnancy ": 3.5330318644832017, "Forced expiratory volume decreased ": 39.84352076104096, "Haemoptysis ": 18.93344787110714, "Hepatic enzyme increased ": 2.1111001056381147, "Hospitalisation ": 37.40684361066212, "Illness ": 5.284251582870279, "Infection ": 9.354718643969102, "Infective pulmonary exacerbation of cystic fibrosis ": 1090.7775353011405, "Influenza ": 3.195248964567396, "Intestinal obstruction ": 5.374002224770848, "Lower respiratory tract infection ": 15.181994393094431, "Lung disorder ": 2.422095250119124, "Lung transplant ": 84.26020092909432, "Mental disorder ": 4.193822873079055, "Nasopharyngitis ": 3.595319619163448, "Oxygen saturation decreased ": 2.0201211412468534, "Pancreatitis ": 6.814419662396732, "Pancreatitis acute ": 2.57172234377964, "Pneumonia ": 7.998431111007434, "Pneumothorax ": 9.462653878567552, "Product dose omission issue ": 7.09454527053352, "Productive cough ": 4.167342664848204, "Pseudomonas infection ": 30.343285991339783, "Pulmonary function test decreased ": 190.13814207809693, "Respiratory failure ": 3.5131431515982703, "Sinusitis ": 6.084885762412976, "Surgery ": 10.038641397065984, "Transaminases increased ": 2.312189477656727, "Treatment noncompliance ": 6.345985023492354, "Viral infection ": 12.728518357098013}
\ No newline at end of file
+{"Accidental overdose": 2.726638118135794, "Acute respiratory distress syndrome": 2.651218122067656, "Altered state of consciousness": 2.2973471479308376, "Anaemia": 4.924874076678786, "Blood pressure decreased": 3.4527533993486945, "Bone marrow failure": 6.176863200144685, "Bone pain": 2.434318070513375, "Cellulitis": 3.11699386572926, "Circulatory collapse": 2.558965281842434, "Cystitis haemorrhagic": 10.950967666655863, "Death": 2.0580944392677543, "Decreased appetite": 2.367421616037176, "Dehydration": 2.01293592477216, "Diarrhoea": 3.213960767984182, "Disease progression": 13.068153446020697, "Disseminated intravascular coagulation": 16.614566679473494, "Enteritis": 6.867742130091692, "Enterocolitis": 8.001727037253637, "Extravasation": 22.20810187434947, "Febrile bone marrow aplasia": 16.468389662816666, "Febrile neutropenia": 85.26930555549139, "Gastrointestinal haemorrhage": 2.072903768233016, "Haematotoxicity": 10.568738710373212, "Haematuria": 8.131462164610689, "Haemoglobin decreased": 2.455683935165222, "Haemorrhage urinary tract": 10.794935028984996, "Hormone-refractory prostate cancer": 42.107361549761535, "Hydronephrosis": 14.960358500526286, "Hypocalcaemia": 3.3145491172610684, "Ileus": 9.83694704904808, "Inappropriate antidiuretic hormone secretion": 3.752455165499272, "Interstitial lung disease": 6.140435186089639, "Intestinal perforation": 7.166339622856966, "Ischaemic hepatitis": 43.06972406313073, "Leukopenia": 6.747596150882283, "Malignant neoplasm progression": 2.209448956152972, "Metastases to bone": 10.591024199035726, "Metastases to liver": 3.2748000465265856, "Metastasis": 10.476867917269118, "Mucosal inflammation": 4.148808423897667, "Multiple organ dysfunction syndrome": 4.186135230579333, "Myelosuppression": 5.919793816580693, "Neuropathy peripheral": 5.723057602062941, "Neurotoxicity": 3.971893911862381, "Neutropenia": 16.756952972495807, "Neutropenic infection": 65.4639443293483, "Neutropenic sepsis": 12.716553873488872, "Neutrophil count decreased": 28.33011497075228, "Osteomyelitis": 5.034794245238509, "Osteonecrosis of jaw": 12.055093389380763, "Pancytopenia": 5.253379999154351, "Performance status decreased": 8.830975425837613, "Physical deconditioning": 7.954452546646241, "Platelet count decreased": 5.355441108827202, "Pleural effusion": 2.190861740523838, "Pneumonia": 2.827472358226308, "Pneumonia aspiration": 2.280098098708521, "Pneumonia bacterial": 16.179885360866663, "Product dispensing error": 6.758245194668755, "Product storage error": 3.4817700319491998, "Prostate cancer": 8.027783234947151, "Prostate cancer metastatic": 20.39173520269268, "Prostatic specific antigen increased": 73.54458657594722, "Respiratory failure": 2.401549004650029, "Sepsis": 9.260466592326614, "Septic shock": 19.48714477896724, "Shock": 4.774154670816518, "Taste disorder": 2.8075736469532875, "Thrombocytopenia": 4.454701350026967, "Tumour lysis syndrome": 8.03179958758369, "White blood cell count decreased": 5.9411736485686095, "White blood cell count increased": 2.411782249584394}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/617.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/617.json
index 76580cf4b8d..fe88b4e4243 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/617.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/617.json
@@ -1 +1 @@
-{"Chills ": 5.29118140427494, "Off label use ": 9.696878321314324}
\ No newline at end of file
+{"Angioedema": 79.35818143004069, "Death": 13.770272579478965}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/618.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/618.json
index c22b96af1a6..82cbc33d7d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/618.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/618.json
@@ -1 +1 @@
-{"Acute kidney injury ": 5.454048554662987, "Angioedema ": 8.718896859635164, "Blood pressure increased ": 7.1385618572660565, "Cardiac failure ": 2.4031115456880623, "Cough ": 3.5418484600312663, "Hyperkalaemia ": 26.84115267850989, "Hypertension ": 2.3184099723719807, "Hyponatraemia ": 6.337541657451082, "Hypotension ": 6.889319793358886, "Muscle spasms ": 2.107211367889008, "Nasopharyngitis ": 2.2712750421827206, "Neutropenia ": 3.388512342282296, "Orthostatic hypotension ": 9.627466976359532, "Presyncope ": 11.031226228445153, "Renal failure ": 2.037714341154249, "Swelling face ": 3.0261685818216084, "Syncope ": 2.7685604600654976, "Vertigo ": 2.2446032418181536, "Vulvovaginal candidiasis ": 155.6799966179927, "Weight decreased ": 2.619495660694392}
\ No newline at end of file
+{"Haemarthrosis": 651.8662961820921, "Haemorrhage": 67.11805663276392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/619.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/619.json
index 194017ecf99..9076e052327 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/619.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/619.json
@@ -1 +1 @@
-{"Acute kidney injury ": 8.98497758771396, "Angioedema ": 6.88749549810547, "Blood pressure increased ": 2.973145483302433, "Blood sodium decreased ": 37.23097521524178, "Bradycardia ": 4.744831603235164, "Drug interaction ": 2.643397773288292, "Hyperkalaemia ": 12.970275288876197, "Hypokalaemia ": 14.04686425956964, "Hyponatraemia ": 22.422652401041617, "Hypotension ": 10.432705039241588, "Lactic acidosis ": 11.08753621334067, "Presyncope ": 6.236679600672139, "Syncope ": 4.962151924045536, "Vertigo ": 3.800464072838746}
\ No newline at end of file
+{"Abdominal pain upper": 3.1723417888235743, "Dysgeusia": 14.826606885304164, "Dysphagia": 8.012679659514697, "Inappropriate schedule of product administration": 8.710665684569504, "Infection susceptibility increased": 534.3324132541065, "Oesophageal candidiasis": 321.3204320895036, "Off label use": 4.678339341191665, "Oral candidiasis": 97.95356823430126}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/62.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/62.json
index 95975aaa947..82be3661e81 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/62.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/62.json
@@ -1 +1 @@
-{"Syncope ": 4.986117072753408}
\ No newline at end of file
+{"Asthenia": 5.698201700647485, "Nausea": 4.79913268920868, "Neutropenia": 25.442439393492062}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/620.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/620.json
index 65421c1984b..05779258b9d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/620.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/620.json
@@ -1 +1 @@
-{"Application site erythema ": 167.28006146326328, "Application site pain ": 9.698582669459917, "Application site pruritus ": 266.6039195958152, "Application site rash ": 130.10739102167346, "Application site reaction ": 68.09048612112686, "Dry mouth ": 11.516030169726738, "Erythema ": 2.96951667317266, "Product adhesion issue ": 266.19442500055175, "Product complaint ": 13.701573838435705, "Vision blurred ": 4.3785248553856}
\ No newline at end of file
+{"Disease progression": 9.9664621922306, "Neuropathy peripheral": 6.672529150802298, "Platelet count decreased": 5.804759821534628, "Thrombocytopenia": 4.388271820188486}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/621.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/621.json
index 8f6768bfde2..f1755aadc18 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/621.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/621.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 5.757633111326372, "Abortion ": 4.8980690023963165, "Abortion induced ": 6.113819021648333, "Abortion missed ": 2.200638191502839, "Abortion spontaneous ": 4.10725222549644, "Accident ": 2.2705055821711326, "Accidental exposure to product ": 6.332085968901976, "Accidental exposure to product by child ": 2.6672596517651765, "Accidental overdose ": 2.666038507763053, "Acute psychosis ": 9.31230073203831, "Adverse drug reaction ": 4.460738890619583, "Affect lability ": 4.184311819798195, "Affective disorder ": 11.313819744117389, "Aggression ": 14.279978471850908, "Agitation ": 4.302283570361107, "Agranulocytosis ": 3.045904103465473, "Alcohol abuse ": 2.443296946676045, "Ammonia increased ": 3.571617882690985, "Amnesia ": 3.9687668562683567, "Anger ": 11.92436980786837, "Anisocoria ": 2.8629642013006724, "Anticonvulsant drug level abnormal ": 23.470658096024444, "Anticonvulsant drug level above therapeutic ": 10.518731967446165, "Anticonvulsant drug level below therapeutic ": 15.615018967311784, "Anticonvulsant drug level decreased ": 10.621659216411144, "Anticonvulsant drug level increased ": 11.998846866472894, "Apathy ": 3.934914570091265, "Aphasia ": 3.311014649204485, "Aplastic anaemia ": 3.763056019836746, "Apraxia ": 2.399066587772965, "Arnold-Chiari malformation ": 8.755418048586838, "Aspiration ": 3.2708359419541377, "Asthenopia ": 2.401668937120003, "Ataxia ": 5.81927392658869, "Atonic seizures ": 12.088804075393584, "Atrial septal defect ": 4.035505845829315, "Atrophy ": 3.1631709644460155, "Attention deficit hyperactivity disorder ": 3.677042260618155, "Auditory disorder ": 2.074177574851125, "Aura ": 32.08587219672359, "Autism spectrum disorder ": 2.688855080281759, "Balance disorder ": 3.131108974804805, "Behaviour disorder ": 17.139801753794504, "Bradycardia neonatal ": 6.761482244214876, "Bradyphrenia ": 3.945759816831539, "Brain injury ": 3.660031903072309, "Brain lobectomy ": 75.9123719669328, "Brain malformation ": 12.299209478137312, "Brain neoplasm ": 10.139283232516377, "Brain neoplasm malignant ": 2.1869702671416995, "Brain oedema ": 2.955277752189278, "Brain operation ": 42.373009872605486, "Breast feeding ": 4.431388638403933, "Bronchial obstruction ": 2.347639169368977, "Caesarean section ": 9.446071649026395, "Calcinosis ": 2.8777720916993137, "Catatonia ": 4.751637999039611, "Cell death ": 6.621290721726646, "Cerebellar atrophy ": 3.1839108682102157, "Cerebellar syndrome ": 3.1606613623561204, "Cerebral arteriovenous malformation haemorrhagic ": 148.22088956427817, "Cerebral disorder ": 2.034030680940458, "Cerebrospinal fluid leakage ": 3.182914556276959, "Cervical vertebral fracture ": 2.0915832524353646, "Change in seizure presentation ": 34.78788256257526, "Cholestasis ": 5.182416925331632, "Clavicle fracture ": 2.5179993387763253, "Cleft lip ": 7.465381020256768, "Cleft lip and palate ": 12.778271162091464, "Cleft palate ": 8.488709476661263, "Clonic convulsion ": 2.6584577729989736, "Clonus ": 4.078720109040956, "Clumsiness ": 3.167596597194647, "Cognitive disorder ": 4.142815939588838, "Coma ": 2.6706483891023045, "Communication disorder ": 3.389744535924321, "Concussion ": 3.8571530697039513, "Confusional state ": 2.1903142775443274, "Congenital central nervous system anomaly ": 5.150417628381677, "Congenital foot malformation ": 10.300130062203094, "Congenital musculoskeletal disorder ": 3.949708801111435, "Congenital musculoskeletal disorder of limbs ": 6.049825394161366, "Convulsive threshold lowered ": 32.52956984647942, "Coordination abnormal ": 3.722329249092194, "Craniocerebral injury ": 5.531104310458717, "Craniofacial fracture ": 6.769142170063106, "Craniotomy ": 11.254252410988618, "Crying ": 2.3069982361121424, "Cryptorchism ": 6.459990192118634, "Daydreaming ": 4.345350039322753, "Deja vu ": 30.663594594694324, "Delusion ": 3.631375750954594, "Depersonalisation/derealisation disorder ": 3.327241618698468, "Depressed mood ": 3.077721966448562, "Depression ": 4.356320755418045, "Depressive symptom ": 2.3302092122696227, "Dermatitis exfoliative ": 2.302434992972663, "Developmental delay ": 5.960445685552384, "Diastolic hypotension ": 22.43941175487668, "Diet failure ": 173.16905913001102, "Diplopia ": 3.1220804640182958, "Disability ": 2.72735157256043, "Disinhibition ": 2.1520247969277677, "Disorientation ": 2.038263789998801, "Disturbance in attention ": 2.7355719311997437, "Drooling ": 3.611049959182215, "Drop attacks ": 6.2628449371298265, "Drug level below therapeutic ": 2.687856974715756, "Drug level decreased ": 4.16025677473194, "Drug level increased ": 2.210789427682471, "Drug reaction with eosinophilia and systemic symptoms ": 5.798227201115124, "Drug screen positive ": 4.244443078178049, "Drug withdrawal convulsions ": 7.364300211132145, "Dysarthria ": 2.5200735864380253, "Dyschromatopsia ": 2.3415591959483297, "Dysgraphia ": 2.641776334911854, "Dyskinesia ": 2.7995991065862977, "Dysmorphism ": 4.952809945503441, "Dysphemia ": 5.51746363042228, "Dystonia ": 2.14858851614556, "Ectopic pregnancy ": 2.0875163270944563, "Educational problem ": 5.576731603440408, "Electroencephalogram abnormal ": 7.726045408301603, "Emotional disorder ": 5.790914978456578, "Encephalitis autoimmune ": 6.880053628296253, "Encephalopathy ": 4.723352314775207, "Enuresis ": 2.9495723465806414, "Eosinophilia ": 2.706130257589919, "Epilepsy ": 13.630823714401307, "Epilepsy congenital ": 42.57156213248659, "Epileptic aura ": 15.360029796129202, "Exophthalmos ": 3.328970420079228, "Exposure via breast milk ": 4.812187527077993, "Face injury ": 4.789868505827508, "Feeling drunk ": 3.227438883213051, "Fibroadenoma of breast ": 5.975838529198811, "Flight of ideas ": 9.800274787158592, "Focal dyscognitive seizures ": 58.98607733155528, "Foetal anticonvulsant syndrome ": 3.4285693342522605, "Foetal death ": 2.5248137233410244, "Foetal distress syndrome ": 2.735638230264219, "Foetal exposure during pregnancy ": 2.3197007003555683, "Foetal growth restriction ": 4.650077910988972, "Foetal malformation ": 11.826394744251704, "Foetal malnutrition ": 22.90792089754053, "Food aversion ": 2.1329299066659426, "Food interaction ": 2.5189865058628635, "Frustration tolerance decreased ": 3.2637170954778822, "Gamma-glutamyltransferase increased ": 2.1879518590832103, "Gastrointestinal tube insertion ": 2.255196536636124, "Generalised tonic-clonic seizure ": 22.691509797373524, "Gingival disorder ": 3.96193335203925, "Gingival hypertrophy ": 4.36251703539421, "Gingival recession ": 4.559689343370957, "Gingival swelling ": 3.1867055273932308, "Glioblastoma ": 13.13220802569392, "Glioblastoma multiforme ": 14.24832925259962, "Glioma ": 10.192927219759229, "Growth retardation ": 3.8445530073409455, "Haemangioma ": 2.534742271829902, "Hallucination ": 3.261779059277813, "Hallucination, auditory ": 3.9479046521429058, "Hallucination, visual ": 3.675635395878644, "Head injury ": 3.2505317147597084, "Head titubation ": 4.238065300472702, "Hepatic cytolysis ": 4.685534274243059, "Hepatic failure ": 2.011918240376368, "Hepatitis acute ": 2.148045112461197, "Homicidal ideation ": 3.657188906861641, "Hostility ": 14.146770505240656, "Hyperammonaemia ": 4.216449703602315, "Hypersomnia ": 3.1867114239231267, "Hypertonia ": 3.344390891354098, "Hypoglycaemia neonatal ": 2.972033016891591, "Hypomania ": 2.699385322973444, "Hyponatraemia ": 2.3129990946120937, "Hyponatraemic syndrome ": 6.912856548091505, "Hypospadias ": 4.90260679666417, "Hypothermia ": 3.330552349857597, "Hypotonia ": 2.408479151492726, "Hypotonia neonatal ": 5.599414634373877, "Hypovitaminosis ": 4.322584251932325, "Ileus paralytic ": 2.813218186823406, "Impatience ": 6.789559130478277, "Implant site erosion ": 15.365046518605595, "Implant site extravasation ": 20.610864628454262, "Implant site infection ": 15.953362756460644, "Implant site swelling ": 20.377184296984304, "Impulsive behaviour ": 4.837932344503909, "Inability to afford medication ": 2.144046934425343, "Inappropriate antidiuretic hormone secretion ": 2.8464149906105067, "Induced labour ": 10.985256136668514, "Infantile apnoea ": 3.973170445646228, "Infantile spasms ": 7.414556321326129, "Inhibitory drug interaction ": 3.3930176656304183, "Intellectual disability ": 2.9869003578834934, "Intentional self-injury ": 2.0498707183864022, "Intracranial pressure increased ": 2.690756153867914, "Irritability ": 7.34318230157772, "Jaundice neonatal ": 3.526849387671743, "Language disorder ": 2.3190226428362197, "Large for dates baby ": 4.936848750049724, "Learning disability ": 4.172058735368958, "Learning disorder ": 4.947956250178342, "Lennox-Gastaut syndrome ": 39.79996604871586, "Leukopenia ": 3.10137704014513, "Lip injury ": 3.406737208157162, "Liver function test increased ": 2.1936848038861623, "Logorrhoea ": 3.341601385458941, "Low birth weight baby ": 7.953660196519968, "Low set ears ": 18.53886621780069, "Major depression ": 4.898458763041879, "Maternal exposure before pregnancy ": 14.029717863992246, "Maternal exposure during breast feeding ": 4.968293891651217, "Maternal exposure during pregnancy ": 8.66098384054666, "Medical device site erythema ": 56.36560644688014, "Medical device site fibrosis ": 140.10334883477805, "Memory impairment ": 3.315903651478308, "Meningioma ": 5.428264388703753, "Meningitis bacterial ": 3.8921821733887274, "Mental disorder ": 3.355723460706693, "Mental impairment ": 2.7675201001747585, "Mental status changes ": 2.238745380779076, "Metabolic disorder ": 3.073114908022468, "Metabolic encephalopathy ": 2.760233712987468, "Microcephaly ": 8.783099123555639, "Miosis ": 2.130490878890328, "Mixed anxiety and depressive disorder ": 3.5784708307580257, "Mixed liver injury ": 2.812450387597942, "Mood altered ": 5.5496277945870505, "Mood swings ": 8.014207195521426, "Morbid thoughts ": 8.47177729143926, "Motor developmental delay ": 6.633354691234914, "Multiple congenital abnormalities ": 3.3469187944263923, "Multiple-drug resistance ": 32.05695506524039, "Muscle spasticity ": 2.569772833860457, "Muscle twitching ": 2.3087175839871747, "Mutism ": 5.781697817227845, "Myoclonic epilepsy ": 39.77733889882512, "Myoclonus ": 5.136093523856046, "Nasal pruritus ": 2.2751141661865315, "Negative thoughts ": 4.214585880133037, "Neonatal respiratory distress ": 4.434210431631492, "Neonatal respiratory distress syndrome ": 7.408884349136048, "Nervousness ": 2.534013444914005, "Neurogenic bladder ": 5.055716130057183, "Nonspecific reaction ": 4.064025810870016, "Nose deformity ": 7.3403523726244995, "Nystagmus ": 2.15960321839786, "Obsessive thoughts ": 3.8921821733887274, "Obsessive-compulsive disorder ": 2.485033408505231, "Off label use ": 2.355783776228093, "Optic atrophy ": 4.9864507668882805, "Overdose ": 3.3403727416393214, "Pancytopenia ": 2.967371999404607, "Panic attack ": 2.587018937301792, "Paranoia ": 4.226306789099626, "Partial seizures ": 36.55949668069951, "Partial seizures with secondary generalisation ": 19.223293066564263, "Patent ductus arteriosus ": 4.9851020982742655, "Paternal exposure before pregnancy ": 26.518275989902943, "Perinatal depression ": 9.593312485670609, "Persecutory delusion ": 2.989333532519069, "Perseveration ": 19.181150619546123, "Personality change ": 9.360923562311852, "Personality disorder ": 6.4103180099559705, "Petit mal epilepsy ": 33.76281055809101, "Physical assault ": 7.961523478268476, "Placental disorder ": 5.102457531575547, "Pneumonia aspiration ": 2.742012173483117, "Pneumonia pseudomonal ": 4.458761130232161, "Pneumonia staphylococcal ": 3.931104252029086, "Pneumonitis aspiration ": 4.618967259848595, "Pocket erosion ": 35.78042598318595, "Polydactyly ": 6.870752334737723, "Polyhydramnios ": 3.055436957807088, "Poor feeding infant ": 2.5642801201522647, "Poor sucking reflex ": 10.847342777148116, "Postictal state ": 20.826996837189984, "Pre-eclampsia ": 4.933202242129088, "Precocious puberty ": 7.20328845953537, "Pregnancy ": 20.902290115072876, "Pregnancy on contraceptive ": 8.593821665770419, "Pregnancy on oral contraceptive ": 2.1485143653145045, "Premature baby ": 4.636888109348921, "Premature delivery ": 7.094217648025301, "Premature labour ": 3.437711479443347, "Prescribed overdose ": 2.183719119058245, "Product availability issue ": 6.011075583177427, "Product prescribing error ": 2.0291223239961407, "Product substitution issue ": 2.671227239653394, "Prothrombin time shortened ": 2.1869702671416995, "Psychiatric decompensation ": 5.983303759077355, "Psychiatric symptom ": 2.3921006799074, "Psychogenic seizure ": 13.898352664844046, "Psychomotor hyperactivity ": 5.177193687818671, "Psychomotor retardation ": 2.75442779602126, "Psychomotor skills impaired ": 4.903634329965175, "Psychotic behaviour ": 5.496445119786614, "Psychotic disorder ": 8.429291647987737, "Psychotic symptom ": 2.809785918185543, "Pulmonary valve stenosis ": 3.2678817240477334, "Quadriparesis ": 2.1766144077354044, "Rash maculo-papular ": 2.811049646804213, "Reading disorder ": 2.914259566032516, "Renal aplasia ": 7.226784855403022, "Respiratory acidosis ": 2.0167998514319883, "Respiratory rate decreased ": 2.249677547493772, "Resuscitation ": 3.7383480096237856, "Retrognathia ": 13.164849307692906, "Road traffic accident ": 2.13216943554359, "SARS-CoV-2 test negative ": 2.533607588762712, "Screaming ": 3.908187176926599, "Sedation ": 2.1900639436658604, "Seizure ": 17.915888977898966, "Seizure cluster ": 29.673419533482484, "Self-destructive behaviour ": 8.273992609612744, "Self-injurious ideation ": 3.391359263937669, "Simple partial seizures ": 47.500849804810976, "Skin laceration ": 3.058219787818623, "Sleep deficit ": 2.7782502839505336, "Sleep paralysis ": 5.562104261848378, "Slow response to stimuli ": 2.468516350666987, "Sluggishness ": 2.4203762340102357, "Small for dates baby ": 17.54548811429398, "Social avoidant behaviour ": 3.247288359744438, "Somnolence ": 4.439646969167794, "Sopor ": 4.538474149662102, "Speech disorder ": 3.465666319965071, "Speech disorder developmental ": 2.3775963747562257, "Spina bifida ": 4.085662797612101, "Staphylococcus test positive ": 2.7917286286653487, "Staring ": 7.0045545483767615, "Status epilepticus ": 32.693094686613975, "Stevens-Johnson syndrome ": 5.127180131332464, "Stillbirth ": 2.357729955872664, "Stupor ": 3.6237758844165184, "Substance-induced psychotic disorder ": 2.04871700727991, "Sudden death ": 2.789158769405959, "Sudden unexplained death in epilepsy ": 42.73296686299671, "Suicidal behaviour ": 11.176884936208932, "Suicidal ideation ": 7.095066590535667, "Suicide attempt ": 5.602345788795961, "Systemic infection ": 6.314935411712529, "Systolic hypertension ": 4.126278649887807, "Talipes ": 4.36565914847678, "Temporal lobe epilepsy ": 8.620988439107695, "Teratogenicity ": 35.01663438497142, "Tethered oral tissue ": 12.179153752324716, "Therapeutic product ineffective ": 5.1164702389122825, "Therapy change ": 2.485814916004861, "Therapy interrupted ": 4.179171954744983, "Thinking abnormal ": 3.1135010999094326, "Thrombocytopenia ": 2.982124886432985, "Tic ": 2.48019282059977, "Tongue biting ": 6.8674473329428585, "Tongue injury ": 5.632142380002036, "Tonic convulsion ": 9.583248395021304, "Tooth disorder ": 2.2524269849908403, "Toxic encephalopathy ": 3.4918725130635884, "Toxic epidermal necrolysis ": 5.796241590630328, "Toxic skin eruption ": 2.3288348507470675, "Transaminases increased ": 2.2027551678154618, "Treatment noncompliance ": 3.0218563449361526, "Tumour excision ": 6.791161402033722, "Twin pregnancy ": 24.062238392646528, "Umbilical cord abnormality ": 8.881756108754143, "Umbilical hernia ": 2.111714174555979, "Unevaluable event ": 3.6788389546728366, "Unintended pregnancy ": 9.379003548344048, "Urinary incontinence ": 2.041263588073656, "Urine output increased ": 2.7640426517708674, "Vagal nerve stimulator implantation ": 109.90293221953046, "Ventricular septal defect ": 3.4774512030482283, "Volvulus ": 2.833147889592419, "Walking disability ": 2.008718277515829, "Weight gain poor ": 3.042301605675384, "Wound dehiscence ": 7.564837726083727, "Wound infection staphylococcal ": 7.835741715524683, "Wrong dose ": 6.753798690662763, "Wrong patient ": 15.54106441075508, "Wrong patient received product ": 6.924782833735076, "Wrong product administered ": 2.177022848707355, "Wrong technique in product usage process ": 2.191300379341916}
\ No newline at end of file
+{"Abdominal distension": 2.982390111145841, "Abdominal pain": 3.357044736641943, "Abdominal pain upper": 3.142017601266105, "Abnormal behaviour": 2.142837896252696, "Abortion induced": 5.157557927264396, "Abortion spontaneous": 5.8001346411962, "Acne": 26.7752188845848, "Affect lability": 2.645001303995736, "Affective disorder": 13.549843623781474, "Aggression": 3.909029594468468, "Agitation": 3.206273481095117, "Alanine aminotransferase increased": 7.555270667711369, "Anger": 7.847213999531769, "Anxiety": 2.658561618166926, "Apathy": 3.2200914085244023, "Aspartate aminotransferase increased": 6.566461837958709, "Attention deficit hyperactivity disorder": 10.76606473711668, "Autoimmune hepatitis": 3.849611794023478, "Behaviour disorder": 17.594364430795448, "Bilirubin conjugated increased": 7.558200897996182, "Blood alkaline phosphatase increased": 9.736752964369291, "Blood bilirubin increased": 11.86674155827211, "Blood bilirubin unconjugated increased": 25.475155176632757, "Blood creatine phosphokinase increased": 6.203002277264039, "Body mass index increased": 20.140087967241715, "Brain fog": 4.231525151537546, "Breast enlargement": 6.03492197202286, "Breast pain": 2.4907684862540966, "Bronchial secretion retention": 21.17992551075337, "Butterfly rash": 25.451351606454637, "Cataract": 2.713229694174179, "Chalazion": 247.60721129326456, "Cholecystitis acute": 11.634704464958794, "Cholelithiasis": 3.9111688919837935, "Chromaturia": 2.059914384632265, "Congenital absence of cranial vault": 625.6582724179586, "Constipation": 2.3672374035888075, "Cystic fibrosis": 191.5351994941505, "Delusion": 2.3575120886606955, "Depressed mood": 8.444001270684863, "Depression": 3.963729438393231, "Dermatitis acneiform": 13.763802664955474, "Dermatitis allergic": 2.9869741849390783, "Distal intestinal obstruction syndrome": 742.3862272597287, "Disturbance in attention": 3.034657055474697, "Drug eruption": 4.401510464475299, "Drug-induced liver injury": 4.284226142926364, "Dry eye": 7.324684094347828, "Emotional disorder": 3.6378441948814815, "Eosinophilia": 2.356874577628832, "Epididymitis": 26.1945148525824, "Exposure during pregnancy": 5.293266975677479, "Flatulence": 2.666804060158627, "Forced expiratory volume decreased": 40.28055751195593, "Gamma-glutamyltransferase increased": 4.9716898071290405, "Gestational diabetes": 10.348107517383331, "Gilbert's syndrome": 523.3148854066509, "Gynaecomastia": 3.0767791959763238, "Haemoptysis": 8.35316885671557, "Hemiplegic migraine": 50.69130162964955, "Hepatic cirrhosis": 3.771938892981274, "Hepatic cytolysis": 5.69515228694915, "Hepatic enzyme increased": 3.789026724990945, "Hepatic failure": 2.106352175343083, "Hepatocellular injury": 5.457276526512403, "Hordeolum": 63.239252752044855, "Hospitalisation": 7.683136288879194, "Hyperbilirubinaemia": 14.285295902701291, "Hypertransaminasaemia": 14.8060837661288, "Idiopathic intracranial hypertension": 20.22836243330241, "Illness": 2.272319932190873, "Impulsive behaviour": 16.25844733772006, "Increased bronchial secretion": 10.382756374027831, "Infection": 3.0356386700184377, "Infective pulmonary exacerbation of cystic fibrosis": 108.18848405906286, "Initial insomnia": 21.767582149994027, "Insomnia": 2.5667176845476893, "Intensive care": 24.10695056139572, "Intentional self-injury": 4.270311493327137, "Intestinal obstruction": 2.664130479155897, "Intracranial pressure increased": 17.409540700811423, "Irritability": 4.918817588360969, "Listless": 3.141675727639631, "Lithiasis": 84.95371150424629, "Liver function test abnormal": 2.53425503589539, "Liver function test increased": 9.756472940201933, "Liver transplant": 14.717770180382423, "Lower respiratory tract infection": 17.360559333352267, "Lung disorder": 3.6277272346820846, "Mental disorder": 7.670330024023933, "Middle insomnia": 9.649663743038277, "Mood altered": 7.65757042140317, "Mood swings": 6.107319551790427, "Nasal congestion": 2.0606345838110003, "Nightmare": 2.735220559854177, "Ocular discomfort": 2.4266699517965944, "Orchitis": 32.5590485958551, "Panic attack": 2.810369705558496, "Papilloedema": 19.14009688655715, "Personality change": 4.698837648176494, "Pneumothorax": 2.9039915924271176, "Poor quality sleep": 3.435311893355401, "Portal hypertension": 10.464843654022705, "Productive cough": 15.524968046897744, "Pseudomonas infection": 10.939506083212557, "Psychomotor hyperactivity": 5.674357201283271, "Pulmonary function test decreased": 28.02499813926206, "Pulmonary haemorrhage": 7.277039496858859, "Pulmonary pain": 3.698830111308748, "Rash": 2.9699059232809377, "Rash erythematous": 2.3218581110226064, "Rash macular": 3.268738714450788, "Rash maculo-papular": 5.522877305750843, "Rash pruritic": 5.956154575322761, "Restlessness": 2.0368500877271343, "SARS-CoV-2 test positive": 3.045523213154118, "Secretion discharge": 6.903666666842547, "Self-destructive behaviour": 6.2895820190888365, "Sleep disorder": 6.282256831074131, "Sleep terror": 16.41670604303656, "Sputum increased": 63.78610513550397, "Steatorrhoea": 66.7912255310647, "Suicidal ideation": 2.880078097334986, "Surgery": 8.295577242872083, "Sweat test abnormal": 755.7543833475393, "Testicular pain": 22.404519829163736, "Tic": 6.3896159072256005, "Transaminases increased": 10.846869362864496, "Transplant": 29.97997883974379, "Vaginal discharge": 2.264192554346999, "Viral infection": 6.681906169537426, "Vitamin A increased": 1523.5665143061224}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/622.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/622.json
index 235a2ea1124..b6e245c57ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/622.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/622.json
@@ -1 +1 @@
-{"Hyperkalaemia ": 100.97790017031684}
\ No newline at end of file
+{"Abdominal hernia": 5.407843969586612, "Abdominal tenderness": 2.464720455677494, "Abortion induced": 12.278900884533607, "Abortion spontaneous": 3.588447613279776, "Accidental overdose": 2.0168152467758995, "Acquired immunodeficiency syndrome": 61.78128357706783, "Acrochordon": 29.811796886167265, "Acute hepatic failure": 3.1794869466521987, "Acute kidney injury": 3.4186329334257475, "Acute respiratory distress syndrome": 5.862769527333646, "Adrenal insufficiency": 3.815153161618192, "Adrenal suppression": 10.210348998605026, "Alanine aminotransferase increased": 2.0761707161602394, "Amylase increased": 3.475488870677262, "Anaemia": 2.5297528286488475, "Anaemia macrocytic": 5.241635182301193, "Anogenital warts": 55.25009863770435, "Anti-neutrophil cytoplasmic antibody positive vasculitis": 16.355469582221016, "Antiviral drug level above therapeutic": 303.62655420483634, "Arterial spasm": 60.86101401802448, "Aspartate aminotransferase increased": 2.1180373198231472, "Aspiration bursa": 1041.6651607132662, "Atrial septal defect": 3.097888882328736, "Atrioventricular block": 2.5326543317386254, "Atrioventricular block complete": 3.343938852244278, "Atrioventricular block first degree": 3.889393919103244, "Autoimmune thyroiditis": 5.556058294561598, "Behaviour disorder": 2.56335773884294, "Benign prostatic hyperplasia": 11.598366996517209, "Bilirubin conjugated increased": 7.593801338333776, "Biopsy liver abnormal": 32.78001317811359, "Blood HIV RNA increased": 24.327525491333688, "Blood bilirubin increased": 3.0048109350796084, "Blood bilirubin unconjugated increased": 16.716819883680298, "Blood creatinine abnormal": 4.242064739075973, "Blood creatinine increased": 2.2805696457474647, "Blood lactate dehydrogenase increased": 2.6986942215149314, "Blood lactic acid increased": 6.32462536540212, "Blood triglycerides increased": 12.05018826184497, "Bone demineralisation": 3.98521958879692, "Bone density decreased": 5.300892890983549, "Bone loss": 8.444498754134223, "Bone marrow failure": 2.829339129371076, "Bone metabolism disorder": 92.42925927340475, "Bradycardia": 2.106171559740744, "Breath odour": 7.010408486364128, "CD4 lymphocytes decreased": 37.351141508248496, "COVID-19 treatment": 465.5448005527561, "Cachexia": 14.551918308877196, "Caesarean section": 8.449028465782801, "Cardiac murmur": 2.4204009370316686, "Carotid artery stenosis": 5.31877870624355, "Cerebellar syndrome": 8.909060317757262, "Cerebral toxoplasmosis": 23.631283337123367, "Cholestasis": 6.010254596558652, "Chronic kidney disease": 3.676307014415471, "Coarctation of the aorta": 12.568011215855671, "Congenital anomaly": 3.557357523119804, "Congenital aplasia": 10.567118124861814, "Congenital hearing disorder": 83.80018417855474, "Coronavirus infection": 3.78217666679326, "Cortisol decreased": 11.619212034519524, "Cryptorchism": 10.590789774317493, "Cushing's syndrome": 47.3937118305524, "Cushingoid": 15.805306307783368, "Cyst": 2.8367953289470624, "Cytomegalovirus chorioretinitis": 7.165439827711759, "Cytomegalovirus infection": 2.1117996898821976, "Developmental delay": 4.217324340648887, "Diarrhoea": 3.267518047052857, "Drug interaction": 4.375025956887761, "Drug level changed": 22.530334227083223, "Drug level decreased": 2.4322068800578385, "Drug level increased": 7.889974125175983, "Drug-induced liver injury": 2.1510083163691984, "Dyslipidaemia": 22.44857404701054, "Dysmorphism": 2.923460574139013, "Economic problem": 2.509315768417807, "Electrocardiogram QT prolonged": 6.9592594429688805, "Electrocardiogram abnormal": 2.8061185953535777, "Electrolyte imbalance": 2.969301936316937, "Encephalitis": 2.4523281620958817, "Endotracheal intubation": 15.179993097778643, "Ergot poisoning": 43.67801909105801, "Erythema nodosum": 3.424424196127956, "Eyelid ptosis": 2.818267765747361, "Fanconi syndrome": 56.59641837907686, "Fanconi syndrome acquired": 11.446248608364026, "Fat redistribution": 46.16791685529153, "Foetal death": 5.3430083497887, "Foetal distress syndrome": 6.998166371588082, "Foetal exposure during pregnancy": 4.5087321968616045, "Foetal growth restriction": 4.39548335946102, "Foot fracture": 2.928405600536122, "Fracture": 11.1530863789869, "Gamma-glutamyltransferase increased": 2.51512850260092, "Gastritis": 2.915218589387468, "Gastrointestinal disorder": 2.5768261881287984, "Glomerular filtration rate abnormal": 6.5503082776078925, "Glycosuria": 7.480753479581756, "HIV infection": 14.629881321238097, "HIV test positive": 26.43681284633029, "Hepatic cancer": 4.897187297161806, "Hepatic cytolysis": 12.532949301336668, "Hepatic failure": 2.8119423100291447, "Hepatic lesion": 4.611536250781388, "Hepatitis": 4.737927218928912, "Hepatitis acute": 2.928877671509451, "Hepatocellular injury": 7.006693446318263, "Hepatomegaly": 4.778546246777942, "Hepatosplenomegaly": 4.139109899819189, "Hepatotoxicity": 3.965792942378605, "Herpes virus infection": 2.807230150837427, "Hip fracture": 3.120915373442186, "Hip surgery": 4.53135758467981, "Hodgkin's disease": 5.964195033071367, "Humerus fracture": 11.83041438444896, "Hydrocephalus": 3.8726069375113, "Hyperbilirubinaemia": 11.240961552227372, "Hypercholesterolaemia": 4.609593855989078, "Hyperlactacidaemia": 18.5598132830562, "Hyperlipasaemia": 15.7307463277005, "Hyperlipidaemia": 4.686529926649116, "Hypertransaminasaemia": 11.52002020087891, "Hypertriglyceridaemia": 57.19398421371701, "Hypophagia": 2.3748300478915567, "Hypophosphataemia": 12.547630196477364, "Hypospadias": 5.774025128155651, "Ileus paralytic": 5.422687216840202, "Immune reconstitution inflammatory syndrome": 24.57381358395608, "Immunosuppressant drug level increased": 13.960367470115209, "Incoherent": 2.999461786798583, "Jaundice": 4.995990328913504, "Kaposi's sarcoma": 16.649047658593556, "Kidney infection": 5.590532186095822, "Kidney malformation": 27.202398331586476, "Lactic acidosis": 5.486092874780975, "Lipase increased": 6.005976431710357, "Lipids increased": 14.103452350444083, "Lipoatrophy": 10.604609818305931, "Lipodystrophy acquired": 20.463066708387498, "Live birth": 7.091758493291437, "Liver function test abnormal": 4.85775336684908, "Long QT syndrome": 25.91751561065719, "Lymphoma": 2.79910283488415, "Lymphopenia": 2.693883248128295, "Magnetic resonance imaging head abnormal": 6.92243600808856, "Mechanical ventilation": 15.431316946353672, "Meningitis cryptococcal": 16.868686392114117, "Mitochondrial toxicity": 16.355001846582013, "Multiple fractures": 6.505344743490132, "Mycobacterium avium complex infection": 7.527825759530812, "Nephrogenic diabetes insipidus": 5.530604254860135, "Nephropathy toxic": 2.8190239226586877, "Non-Hodgkin's lymphoma": 3.196419453294477, "Normal newborn": 3.082458860494372, "Nystagmus": 2.1669161765653526, "Oesophageal atresia": 33.00016053195305, "Oesophageal candidiasis": 12.20647809567552, "Off label use": 3.260001040779223, "Oliguria": 4.353578359069934, "Oral candidiasis": 2.0490313041569874, "Organising pneumonia": 3.4971438846116607, "Osteogenesis imperfecta": 42.53115559064525, "Osteomalacia": 4.4157868983085145, "Osteonecrosis": 10.440076520182428, "Osteopenia": 3.6224422832624943, "Osteoporosis": 6.878812023848671, "Pancreatitis": 2.961568666964829, "Pancreatitis acute": 3.485668774930973, "Patella fracture": 12.765270275072217, "Patent ductus arteriosus": 4.9196655553792095, "Peripheral ischaemia": 4.928891887840357, "Peripheral sensorimotor neuropathy": 10.27184626560527, "Personality disorder": 6.244291477941367, "Pneumocystis jirovecii pneumonia": 4.441955334920688, "Portal hypertension": 4.433199295069733, "Pregnancy on contraceptive": 22.730537888467524, "Premature baby": 3.619660970891001, "Premature delivery": 2.710301706789437, "Premature labour": 4.942066518399148, "Premature rupture of membranes": 14.324163245206146, "Progressive multifocal leukoencephalopathy": 11.558035105725624, "Protein total abnormal": 7.672604103051006, "Proteinuria": 2.612833425096884, "Psychiatric symptom": 3.209432723902557, "Pulmonary tuberculosis": 9.929214700693889, "Pulse absent": 3.3576071084727213, "Pyelocaliectasis": 27.602525332808696, "Renal disorder": 2.422471181386249, "Renal dysplasia": 46.49926162897162, "Renal failure": 4.216409222267768, "Renal injury": 8.144871338373962, "Renal tubular acidosis": 15.663358772859036, "Renal tubular disorder": 10.350931277314428, "Renal tubular necrosis": 8.266553250087705, "Respiratory failure": 2.35387698288236, "Respiratory rate increased": 2.1251294359659343, "Rhabdomyolysis": 2.7316451899779883, "Rhinitis allergic": 2.2084140933921854, "Shoulder fracture": 3.127161626497489, "Sinus bradycardia": 6.113797233157241, "Skeletal injury": 8.029665965661613, "Skin striae": 11.070190004297276, "Small for dates baby": 7.863640013734836, "Stillbirth": 20.99853293378451, "Strabismus": 5.17438382989372, "Sudden death": 2.1657726711618808, "Therapeutic response unexpected": 4.643175424482435, "Tooth disorder": 2.513021536119316, "Tooth fracture": 3.08363057788002, "Tooth loss": 4.527200112661415, "Toxic skin eruption": 2.725658581844227, "Toxoplasmosis": 16.599940512111324, "Transaminases increased": 4.441047423319834, "Tricuspid valve incompetence": 3.0304792734652053, "Trisomy 21": 15.563376011020535, "Tuberculosis": 4.129770877628552, "Unevaluable event": 2.5817772185126358, "Upper limb fracture": 4.229810283022959, "Urinary tract obstruction": 8.909060317757262, "Varices oesophageal": 12.151928202666555, "Ventricular septal defect": 5.8717603809967365, "Viral load increased": 25.403195502780825, "Virologic failure": 4.068130752470712, "Walking disability": 6.187140152641053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/623.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/623.json
index b9cea76ed4b..5b83647280f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/623.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/623.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.745017414611656, "Acne ": 3.275654601448426, "Alopecia ": 2.168174005122785, "B-lymphocyte count decreased ": 284.462427783172, "Blood immunoglobulin G decreased ": 47.53312550050819, "Blood immunoglobulin M decreased ": 222.44735195869603, "Body temperature increased ": 4.055517813646709, "Brain fog ": 2.0216948139048894, "Breast cancer ": 2.3297094260879407, "Bronchitis ": 2.347188477899661, "Central nervous system lesion ": 14.729543421403823, "Coronavirus infection ": 38.14334658421333, "Cystitis noninfective ": 32.19185824680456, "Disease recurrence ": 4.121766049866988, "Gait disturbance ": 3.7844230336159583, "Hemiparesis ": 4.338213268122822, "Hypoaesthesia ": 2.9636502819010446, "Incorrect dose administered by device ": 8.448579496906097, "Infection ": 3.3217266954155638, "Influenza ": 2.7477400831620264, "Influenza like illness ": 6.522479623162985, "Injection related reaction ": 41.89252635681664, "Injection site haemorrhage ": 5.423620175613192, "Listless ": 4.753311765503098, "Liver function test increased ": 2.489360719050035, "Lymphocyte count decreased ": 29.657195624357826, "Lymphopenia ": 9.54347259262302, "Maternal exposure during breast feeding ": 4.468809395352782, "Multiple sclerosis ": 50.33137836897392, "Multiple sclerosis relapse ": 86.02330080684595, "Muscle spasticity ": 8.929703806074848, "Muscular weakness ": 2.325459609638912, "Nasopharyngitis ": 8.46147952859894, "Optic neuritis ": 10.21881080861654, "Oral herpes ": 9.870295650029282, "Oropharyngeal pain ": 3.124306366718031, "Paralysis ": 2.623151903764049, "Relapsing-remitting multiple sclerosis ": 141.534833756436, "Respiratory tract infection ": 3.871728013760523, "Rhinorrhoea ": 3.2106796698796525, "SARS-CoV-2 test positive ": 5.556937183258048, "Secondary progressive multiple sclerosis ": 100.80460411597666, "Sensory disturbance ": 3.839782968214692, "Throat irritation ": 2.211219098823108, "Upper respiratory tract infection ": 2.434798065387689, "Urinary tract infection ": 3.3011410479889527}
\ No newline at end of file
+{"Abortion spontaneous": 2.9975189812819782, "Acne": 4.158813117213652, "Alanine aminotransferase increased": 3.2811975552251385, "Aspartate aminotransferase increased": 2.643279813657028, "Chest discomfort": 2.281842381115077, "Cough": 2.752481445594386, "Cystic fibrosis": 602.1557235459907, "Cystic fibrosis respiratory infection suppression": 1163.827272484795, "Exposure during pregnancy": 3.5330318644832017, "Forced expiratory volume decreased": 39.84352076104096, "Haemoptysis": 18.93344787110714, "Hepatic enzyme increased": 2.1111001056381147, "Hospitalisation": 37.40684361066212, "Illness": 5.284251582870279, "Infection": 9.354718643969102, "Infective pulmonary exacerbation of cystic fibrosis": 1090.7775353011405, "Influenza": 3.195248964567396, "Intestinal obstruction": 5.374002224770848, "Lower respiratory tract infection": 15.181994393094431, "Lung disorder": 2.422095250119124, "Lung transplant": 84.26020092909432, "Mental disorder": 4.193822873079055, "Nasopharyngitis": 3.595045601650902, "Oxygen saturation decreased": 2.0200130677390438, "Pancreatitis": 6.814419662396732, "Pancreatitis acute": 2.57172234377964, "Pneumonia": 7.998431111007434, "Pneumothorax": 9.462653878567552, "Product dose omission issue": 7.09454527053352, "Productive cough": 4.167342664848204, "Pseudomonas infection": 30.343285991339783, "Pulmonary function test decreased": 190.13814207809693, "Respiratory failure": 3.5128530283648525, "Sinusitis": 6.084885762412976, "Surgery": 10.038641397065984, "Transaminases increased": 2.312047895702224, "Treatment noncompliance": 6.345985023492354, "Viral infection": 12.728518357098013}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/624.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/624.json
index 4437aba1078..91f478bd1e7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/624.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/624.json
@@ -1 +1 @@
-{"Off label use ": 9.39940867107983}
\ No newline at end of file
+{"Chills": 5.291165159512767, "Off label use": 9.696496417306651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/625.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/625.json
index abffcb273c5..2abff30fda0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/625.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/625.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 4.355758747178736, "Aspartate aminotransferase increased ": 5.515641905804967, "Chromaturia ": 14.048979455581048, "Drug interaction ": 4.77327077947787, "Drug-induced liver injury ": 7.214618868755462, "Hepatic enzyme increased ": 4.112390649915261, "International normalised ratio increased ": 14.554849425650922, "Jaundice ": 13.372204526990384}
\ No newline at end of file
+{"Acute kidney injury": 5.454048554662987, "Angioedema": 8.718896859635164, "Blood pressure increased": 7.138436527226088, "Cardiac failure": 2.4028922176995944, "Cough": 3.541815604885902, "Hyperkalaemia": 26.837446048475964, "Hypertension": 2.3183860381080845, "Hyponatraemia": 6.337541657451082, "Hypotension": 6.889160470024784, "Muscle spasms": 2.107211367889008, "Nasopharyngitis": 2.2711020069841084, "Neutropenia": 3.388366622450452, "Orthostatic hypotension": 9.62539460574667, "Presyncope": 11.031226228445153, "Renal failure": 2.037714341154249, "Swelling face": 3.0261685818216084, "Syncope": 2.7685223563368093, "Vertigo": 2.2446032418181536, "Vulvovaginal candidiasis": 155.6799966179927, "Weight decreased": 2.619495660694392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/626.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/626.json
index ff11c906395..ff1154554d7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/626.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/626.json
@@ -1 +1 @@
-{"Abdominal distension ": 3.0062006333038283, "Bladder dilatation ": 199.8597747404807, "Blood pressure increased ": 2.813878334244332, "Constipation ": 2.058027656312107, "Disease progression ": 4.512879104731893, "Drug interaction ": 5.277654561802356, "Electrocardiogram QT prolonged ": 4.789970606935725, "Heart rate increased ": 2.483794224687885, "Hypersensitivity ": 2.6482454269344577, "Hypertonia ": 29.58478134540618, "Muscle tightness ": 16.48986926511455, "Musculoskeletal stiffness ": 2.535045555170216, "Oedema peripheral ": 2.753608157937103, "Performance status decreased ": 30.796717521955948, "Respiratory distress ": 5.883485711525176, "Restlessness ": 4.638903363901665, "Subcutaneous abscess ": 74.53458561849743, "Therapy non-responder ": 12.926076507049508, "Urinary incontinence ": 9.487403754425392, "Urinary retention ": 4.849656710869163}
\ No newline at end of file
+{"Acute kidney injury": 8.98497758771396, "Angioedema": 6.88749549810547, "Blood pressure increased": 2.973093305842548, "Blood sodium decreased": 37.23097521524178, "Bradycardia": 4.744682919611394, "Drug interaction": 2.643397773288292, "Hyperkalaemia": 12.968486712503198, "Hypokalaemia": 14.04686425956964, "Hyponatraemia": 22.422652401041617, "Hypotension": 10.432463784240207, "Lactic acidosis": 11.08753621334067, "Presyncope": 6.236679600672139, "Syncope": 4.96208362907364, "Vertigo": 3.800464072838746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/627.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/627.json
index 483cb54ba9f..922abf80f5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/627.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/627.json
@@ -1 +1 @@
-{"Joint swelling ": 6.192097503644567, "Pain ": 2.0493777191454114, "Rheumatoid arthritis ": 11.631571390001218}
\ No newline at end of file
+{"Application site erythema": 167.2531812692705, "Application site pain": 9.697428163479664, "Application site pruritus": 266.6039195958152, "Application site rash": 130.10739102167346, "Application site reaction": 68.09048612112686, "Dry mouth": 11.516030169726738, "Erythema": 2.9694876295125976, "Product adhesion issue": 266.19442500055175, "Product complaint": 13.701573838435705, "Vision blurred": 4.3785248553856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/628.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/628.json
index 1a9f59e68ff..9ca44509f1b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/628.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/628.json
@@ -1 +1 @@
-{"Acute interstitial pneumonitis ": 5.986093193155452, "Acute polyneuropathy ": 5.4238229641812215, "Addison's disease ": 6.864005961426807, "Administration site extravasation ": 2.96330430968245, "Adrenal disorder ": 37.40681010923286, "Adrenal insufficiency ": 49.96298620275996, "Adrenocortical insufficiency acute ": 16.494137195926907, "Adrenocorticotropic hormone deficiency ": 104.73329088046238, "Adverse event ": 12.327030749376284, "Alanine aminotransferase abnormal ": 2.0485290694181604, "Amylase increased ": 4.406406651186828, "Aortic arteriosclerosis ": 2.50238390549157, "Aortitis ": 3.1345859926033364, "Ascites ": 2.281882678551992, "Aspartate aminotransferase abnormal ": 4.52972881642863, "Atelectasis ": 2.748518175538805, "Atrioventricular block complete ": 2.070409462788072, "Autoimmune arthritis ": 32.68431358077445, "Autoimmune colitis ": 37.19573488581798, "Autoimmune haemolytic anaemia ": 6.385468127553972, "Autoimmune hepatitis ": 14.567744735764007, "Autoimmune hypothyroidism ": 47.03496572746179, "Autoimmune lung disease ": 45.09458878332744, "Autoimmune myocarditis ": 71.32749894264413, "Autoimmune myositis ": 26.657440097987852, "Autoimmune nephritis ": 31.257978707578943, "Autoimmune pancreatitis ": 37.87823796219618, "Autoimmune thyroiditis ": 7.63963445084951, "Bladder tamponade ": 9.258182270334702, "Blood albumin decreased ": 2.271197452634864, "Blood alkaline phosphatase abnormal ": 5.584455930761068, "Blood bilirubin abnormal ": 3.345762585899509, "Blood corticotrophin abnormal ": 23.02016556257564, "Blood corticotrophin decreased ": 32.04578747602121, "Blood corticotrophin increased ": 31.93314759589543, "Blood creatine phosphokinase MB increased ": 2.0888918106477794, "Blood creatinine abnormal ": 3.534098452022449, "Blood creatinine decreased ": 2.8285443080813675, "Blood sodium decreased ": 2.344088799512093, "Blood thyroid stimulating hormone abnormal ": 9.8089966110222, "Blood thyroid stimulating hormone decreased ": 11.616221908715366, "Blood thyroid stimulating hormone increased ": 13.781833974038578, "Brain natriuretic peptide increased ": 2.249382105954308, "Brain oedema ": 2.316992445120237, "Breast conserving surgery ": 2.521082005800652, "C-reactive protein increased ": 2.1702735520472367, "Cancer pain ": 12.034035360388511, "Cancer surgery ": 11.258138919158805, "Capillary leak syndrome ": 2.565222654944036, "Carbohydrate antigen 125 increased ": 2.618172139112985, "Carcinoembryonic antigen increased ": 3.885256603698326, "Cardiac dysfunction ": 4.289649672982359, "Cardiac failure acute ": 2.6857047442167103, "Cardiac tamponade ": 7.992568934778222, "Cardiomyopathy ": 2.022878837981948, "Central hypothyroidism ": 15.649534076048342, "Central venous catheterisation ": 5.071598737092821, "Cerebral infarction ": 2.0160098101912625, "Cheilitis ": 2.051553465820028, "Chemotherapy ": 5.387021727562197, "Cholangitis ": 12.698949945278873, "Cholangitis acute ": 4.793585514195206, "Cholangitis sclerosing ": 59.75649593900794, "Cholecystitis ": 5.822201377567525, "Cholecystitis acute ": 5.795574039374032, "Cholestatic liver injury ": 2.39679459204543, "Chronic gastritis ": 2.1285606587851618, "Colitis ": 13.857553310810966, "Colitis microscopic ": 3.859972766733129, "Coronavirus infection ": 3.4957323234854005, "Cortisol abnormal ": 22.80020933166875, "Cortisol decreased ": 17.021529919785316, "Cortisol increased ": 8.853931365442943, "Cutaneous sarcoidosis ": 5.051036220137024, "Cutaneous symptom ": 3.743584237369833, "Cytokine release syndrome ": 2.5720906417111187, "Cytokine storm ": 13.275921568041484, "Cytomegalovirus enterocolitis ": 6.346603054590008, "Cytopenia ": 2.2119957267416464, "Death ": 2.976692462106675, "Decreased appetite ": 2.7461583638884446, "Demyelinating polyneuropathy ": 2.563656516047594, "Dermatitis ": 2.1926421512042102, "Dermatitis psoriasiform ": 7.074087587074197, "Dermatomyositis ": 8.577190348460954, "Device related infection ": 2.6907005772513277, "Diabetes mellitus ": 2.0431317467690926, "Diabetic ketoacidosis ": 3.359984543708683, "Diabetic ketosis ": 3.270607604992777, "Disseminated intravascular coagulation ": 3.681532476172509, "Drug effective for unapproved indication ": 4.97084235701894, "Drug eruption ": 2.7352618133793123, "Drug-induced liver injury ": 2.516915528125013, "Duodenal perforation ": 9.332664121602413, "Duodenal ulcer ": 2.4980881873720278, "Duodenitis ": 2.7261153521413832, "Dysphonia ": 4.051278935993192, "Eastern Cooperative Oncology Group performance status worsened ": 56.974580259183725, "Electrolyte imbalance ": 2.2885065396374, "Encephalitis ": 11.088557889798532, "Encephalitis autoimmune ": 18.750836167847023, "Endocrine disorder ": 9.525666289731902, "Enteritis ": 4.845658164072351, "Enteritis infectious ": 3.897667219372453, "Enterocolitis ": 16.608466108090273, "Enterocolitis haemorrhagic ": 2.117151703327928, "Eosinophil count increased ": 2.956941509458654, "Eosinophil percentage increased ": 6.68440829051359, "Eosinophilic fasciitis ": 13.065277410112246, "Erythema multiforme ": 4.452583286113089, "Eyelid ptosis ": 6.523114892462552, "Febrile bone marrow aplasia ": 4.057783651184814, "Febrile neutropenia ": 2.807997715164142, "Feeding disorder ": 2.406936131048468, "Female genital tract fistula ": 2.490971027051593, "Fistula ": 4.291905273152781, "Fulminant type 1 diabetes mellitus ": 117.9888966304432, "Gallbladder enlargement ": 2.3227715616830014, "Gamma-glutamyltransferase abnormal ": 4.863213612616732, "Gastric perforation ": 3.3627702920868128, "Gastrointestinal oedema ": 4.802839406130677, "Gastrointestinal perforation ": 10.0352383419167, "Gingivitis ": 2.084523558275569, "Glomerulonephritis membranous ": 3.1839275060083363, "Glomerulonephritis rapidly progressive ": 5.415055326807208, "Glucocorticoid deficiency ": 29.36680594561123, "Graves' disease ": 2.151061098207687, "Guillain-Barre syndrome ": 3.1850342270855, "Haemoglobin abnormal ": 4.1613202131235205, "Haemophagocytic lymphohistiocytosis ": 8.293491465441878, "Hepatic cytolysis ": 2.5013597715836724, "Hepatic function abnormal ": 4.693811020261388, "Hepatitis ": 6.661492202102698, "Hepatitis fulminant ": 2.54644489409303, "Hepatotoxicity ": 2.220964745199124, "Hospice care ": 11.291359779707475, "Hydronephrosis ": 4.033803880570942, "Hyperamylasaemia ": 4.407642154162958, "Hyperlipasaemia ": 3.0402100128312384, "Hypertension ": 3.8392457430556126, "Hyperthyroidism ": 16.505104565147377, "Hypertransaminasaemia ": 2.3286141971596277, "Hypoalbuminaemia ": 3.170103430007354, "Hypophysitis ": 39.63832308174628, "Hypopituitarism ": 53.13344385945798, "Hypothalamo-pituitary disorder ": 33.390427184058176, "Hypothyroidism ": 32.01013841738435, "Ileus ": 3.3916147041408395, "Immune thrombocytopenia ": 5.553047716682348, "Immune-mediated adrenal insufficiency ": 259.568585301724, "Immune-mediated adverse reaction ": 106.5273546054814, "Immune-mediated arthritis ": 134.24104214351402, "Immune-mediated cholangitis ": 360.8979806337396, "Immune-mediated cystitis ": 82.35272280888942, "Immune-mediated dermatitis ": 93.16676723494518, "Immune-mediated encephalitis ": 105.58729924737008, "Immune-mediated endocrinopathy ": 88.82862638785676, "Immune-mediated enterocolitis ": 138.07732784991654, "Immune-mediated gastritis ": 108.8962407920274, "Immune-mediated hepatic disorder ": 191.11539641465163, "Immune-mediated hepatitis ": 87.41113155200065, "Immune-mediated hyperthyroidism ": 323.0698645750154, "Immune-mediated hypophysitis ": 42.81127338715039, "Immune-mediated hypothyroidism ": 420.7737835460768, "Immune-mediated lung disease ": 117.05357930986636, "Immune-mediated myasthenia gravis ": 160.6908292634454, "Immune-mediated myocarditis ": 126.54803606564856, "Immune-mediated myositis ": 84.43892864911557, "Immune-mediated nephritis ": 82.38576537543292, "Immune-mediated neurological disorder ": 71.57359804206126, "Immune-mediated neuropathy ": 42.0542566595739, "Immune-mediated pancreatitis ": 175.430043451578, "Immune-mediated pancytopenia ": 86.4566241693717, "Immune-mediated pericarditis ": 128.7659776574867, "Immune-mediated renal disorder ": 231.1922072947446, "Immune-mediated thyroiditis ": 61.85443684482134, "Immune-mediated uveitis ": 130.0459572587717, "Inability to afford medication ": 2.4229405796487637, "Inappropriate antidiuretic hormone secretion ": 2.023099702122953, "Inappropriate schedule of product administration ": 3.30449519163866, "Infectious pleural effusion ": 5.131562851067691, "Infusion site extravasation ": 2.272790940798313, "Interstitial lung disease ": 20.56373056633357, "Intestinal fistula ": 8.197828217190049, "Intestinal perforation ": 5.594446422647323, "Intra-abdominal fluid collection ": 3.8889013239885006, "KL-6 increased ": 25.46344956280277, "Keratitis ": 2.243657324371274, "Large intestinal haemorrhage ": 2.120051534269944, "Large intestine perforation ": 4.593060433584121, "Leukoderma ": 25.213205145039304, "Lichen planus ": 8.401622223797961, "Lichenoid keratosis ": 12.91858344233929, "Lipase increased ": 2.234355698926608, "Liver disorder ": 3.477080683953705, "Loss of therapeutic response ": 2.2156208566144664, "Lung abscess ": 4.36313853510541, "Lung carcinoma cell type unspecified recurrent ": 6.749403110579432, "Lung consolidation ": 2.347257090521638, "Lung disorder ": 3.4140526984933017, "Lung opacity ": 7.0467050434274965, "Lymphadenectomy ": 10.28222482606338, "Lymphadenopathy mediastinal ": 3.961273557154689, "Lymphangiosis carcinomatosa ": 17.71982293759872, "Lymphocytic hypophysitis ": 15.2176430654473, "Malignant ascites ": 15.44114488723946, "Malignant gastrointestinal obstruction ": 40.06616746239568, "Malignant neoplasm oligoprogression ": 42.14701765866408, "Malignant neoplasm progression ": 34.96939152703957, "Malignant pleural effusion ": 16.60076339480707, "Mastectomy ": 3.403633801052591, "Mean cell haemoglobin increased ": 3.238949866378964, "Melanoma recurrent ": 19.4419816727237, "Meningitis ": 4.869034976549676, "Meningitis aseptic ": 2.462047793821412, "Metastases to meninges ": 3.709840129301144, "Metastatic malignant melanoma ": 2.898609733216808, "Mixed liver injury ": 2.315381878790771, "Mucosal inflammation ": 2.7287166109150296, "Myasthenia gravis ": 29.305083589509465, "Myasthenia gravis crisis ": 9.84488804159934, "Myasthenic syndrome ": 15.890342360489829, "Myelosuppression ": 2.060662072085421, "Myocardial necrosis marker increased ": 3.077639447265126, "Myocarditis ": 6.149165904754061, "Myositis ": 20.54695776918828, "Necrotising fasciitis ": 2.362435914068973, "Necrotising myositis ": 15.268277178365915, "Nephritis ": 33.22766256792849, "Nephrotic syndrome ": 3.1504359303777854, "Neuromyopathy ": 2.317973310484395, "Neuropathy peripheral ": 2.544813082403208, "Neutrophil count decreased ": 2.842167648314213, "Non-small cell lung cancer recurrent ": 16.987094632975086, "Nutritional condition abnormal ": 5.223122764657142, "Ocular myasthenia ": 11.793309206194769, "Oesophageal perforation ": 6.376720843017223, "Oesophageal stenosis ": 3.139119323043714, "Ophthalmoplegia ": 2.5570750976371146, "Optic neuritis ": 3.257634972181272, "Oral mucosa erosion ": 2.8422271894390527, "Organising pneumonia ": 15.58186271957175, "Oxygen saturation abnormal ": 3.268273782571876, "Oxygen therapy ": 4.168712712046613, "Palliative care ": 6.598997586342115, "Palmar-plantar erythrodysaesthesia syndrome ": 8.739637151379464, "Pancreatic enzymes increased ": 2.742036346706606, "Pancreatic failure ": 3.436255674831981, "Paraneoplastic syndrome ": 12.313563280528632, "Pathological fracture ": 2.0494406788511426, "Pemphigoid ": 13.813117370311137, "Perforation ": 8.080314761591087, "Pericardial effusion ": 3.4181474689127325, "Pericarditis malignant ": 96.00996264380446, "Physical deconditioning ": 3.0615832036279764, "Platelet count decreased ": 4.407596357491915, "Pleural effusion ": 3.7989200562171, "Pneumatosis intestinalis ": 3.6030559072700488, "Pneumocystis jirovecii pneumonia ": 4.056222237555544, "Pneumonia ": 2.1587068689823843, "Pneumonia aspiration ": 3.5323653893658764, "Pneumonia bacterial ": 9.303075547112124, "Pneumonitis ": 23.006069446903247, "Pneumothorax ": 4.381583129605632, "Polyarthritis ": 6.085150867459725, "Polymyalgia rheumatica ": 6.824011134335908, "Polymyositis ": 8.695467953802197, "Posterior reversible encephalopathy syndrome ": 2.826861594893625, "Postrenal failure ": 11.618461616540635, "Prerenal failure ": 5.650137096600775, "Primary adrenal insufficiency ": 18.042906794702397, "Primary hypothyroidism ": 14.76351931431538, "Procalcitonin increased ": 4.277540214792153, "Product use in unapproved indication ": 5.99283082521169, "Product use issue ": 2.923306400686949, "Protein urine ": 13.279910423362985, "Protein urine present ": 3.671743505746551, "Proteinuria ": 13.234297614067325, "Psoas abscess ": 4.578429259945913, "Pulmonary sarcoidosis ": 6.525933753424509, "Pulmonary toxicity ": 9.431170679849703, "Pyelonephritis ": 2.826087413081574, "Radiation injury ": 6.785455178615529, "Radiation pneumonitis ": 32.071035686315774, "Radiotherapy ": 21.86230494983322, "Rectal perforation ": 10.672991937282085, "Recurrent cancer ": 8.020456064420685, "Red blood cell count abnormal ": 3.739268058052948, "Red blood cell count increased ": 2.200138244218991, "Red blood cell transfusion ": 4.160238052556816, "Renal impairment ": 3.271374438672857, "Renal tubular acidosis ": 2.5978217374799946, "Respiratory failure ": 2.0185431064724373, "Retroperitoneal fibrosis ": 5.475377659097775, "Rheumatic disorder ": 2.151300969877792, "Salivary hyposecretion ": 4.113975646860011, "Sarcoidosis ": 4.18336099069734, "Secondary adrenocortical insufficiency ": 34.77683289321213, "Septic shock ": 2.7713121369408737, "Seronegative arthritis ": 3.897667219372453, "Sialoadenitis ": 6.638637429754011, "Silent thyroiditis ": 63.60152730447131, "Sjogren's syndrome ": 6.088956732040036, "Skin disorder ": 3.933132847427425, "Skin toxicity ": 6.805813742651205, "Small intestinal haemorrhage ": 2.941486796233526, "Small intestinal perforation ": 20.730919977985277, "Stevens-Johnson syndrome ": 3.947256634557669, "Stomatitis ": 4.168139959605727, "Stress cardiomyopathy ": 3.0530301926649046, "Subacute cutaneous lupus erythematosus ": 3.047388383134796, "Superior vena cava syndrome ": 5.811532128127838, "Therapeutic response increased ": 2.296364519186749, "Therapy partial responder ": 15.82749299302865, "Thrombophlebitis migrans ": 46.02028782073444, "Thyroid disorder ": 11.239268356469314, "Thyroid function test abnormal ": 5.692708112050763, "Thyroid hormones decreased ": 14.120365693186525, "Thyroid hormones increased ": 8.041315214246424, "Thyroiditis ": 39.6958368585039, "Thyroiditis subacute ": 2.6349511871933253, "Thyrotoxic crisis ": 9.139962402598456, "Thyroxine free decreased ": 5.201735905959504, "Thyroxine free increased ": 6.18934622980978, "Toxic epidermal necrolysis ": 3.443885010688703, "Transfusion ": 2.2354890584980778, "Tri-iodothyronine free decreased ": 18.204563809112955, "Tri-iodothyronine free increased ": 18.72279381698133, "Troponin I increased ": 2.9124180961415327, "Troponin T increased ": 3.580713761794635, "Troponin increased ": 4.445853439112568, "Tubulointerstitial nephritis ": 10.747953288241854, "Tumour associated fever ": 51.060604991998346, "Tumour haemorrhage ": 7.391718511988311, "Tumour hyperprogression ": 100.93320344107418, "Tumour lysis syndrome ": 3.0199734313850017, "Tumour marker increased ": 3.551644976559348, "Tumour necrosis ": 15.667133427577475, "Tumour pain ": 6.876141952934418, "Tumour pseudoprogression ": 81.37858774211624, "Type 1 diabetes mellitus ": 34.41108926411956, "Urogenital fistula ": 37.388884063769616, "Uveitis ": 4.246183516964763, "Vitiligo ": 19.69859570869667, "Vocal cord paralysis ": 2.095050262815306, "Vogt-Koyanagi-Harada disease ": 9.601844134459114, "Warm autoimmune haemolytic anaemia ": 14.567657279620676}
\ No newline at end of file
+{"Abnormal behaviour": 5.756936452959672, "Abortion": 4.8974764052425614, "Abortion induced": 6.1130793150500295, "Abortion missed": 2.200371953678508, "Abortion spontaneous": 4.106755260062297, "Accident": 2.270230885605653, "Accidental exposure to product": 6.3313198248933, "Accidental exposure to product by child": 2.6669369548944286, "Accidental overdose": 2.665715939114686, "Acute psychosis": 9.311174072780108, "Adverse drug reaction": 4.460199161785076, "Affect lability": 4.1838055624258015, "Affective disorder": 11.31245086719104, "Aggression": 14.27825035064523, "Agitation": 4.30176296930408, "Agranulocytosis": 3.04553555914662, "Alcohol abuse": 2.443001347224849, "Ammonia increased": 3.57118576963517, "Amnesia": 3.968286633825159, "Anger": 11.922926947431003, "Anisocoria": 2.862617832475548, "Anticonvulsant drug level abnormal": 23.467818565260785, "Anticonvulsant drug level above therapeutic": 10.517459379000629, "Anticonvulsant drug level below therapeutic": 15.613129793324951, "Anticonvulsant drug level decreased": 10.620374147846348, "Anticonvulsant drug level increased": 11.997395172019864, "Apathy": 3.934438478680909, "Aphasia": 3.3101144596496765, "Aplastic anaemia": 3.762600739027637, "Apraxia": 2.3987763436716176, "Arnold-Chiari malformation": 8.754358791036903, "Aspiration": 3.2704402130765966, "Asthenopia": 2.401378373691028, "Ataxia": 5.818569829368833, "Atonic seizures": 12.087341520354796, "Atrial septal defect": 4.035017599409113, "Atrophy": 3.1627882763509585, "Attention deficit hyperactivity disorder": 3.6765973924171336, "Auditory disorder": 2.0739266354514805, "Aura": 32.08199012750153, "Autism spectrum disorder": 2.687610712276309, "Balance disorder": 3.130730108017715, "Behaviour disorder": 17.137727840557282, "Bradycardia neonatal": 6.760664222956425, "Bradyphrenia": 3.945282432521906, "Brain injury": 3.659589083540871, "Brain lobectomy": 75.90318793611925, "Brain malformation": 12.297721493526062, "Brain neoplasm": 10.138056478812556, "Brain neoplasm malignant": 2.18670568250981, "Brain oedema": 2.9549201986966933, "Brain operation": 42.367883211935066, "Breast feeding": 4.43085251984712, "Bronchial obstruction": 2.347355146261094, "Caesarean section": 9.444928757228002, "Calcinosis": 2.877423932822298, "Catatonia": 4.751063121539212, "Cell death": 6.620489645626279, "Cerebellar atrophy": 3.1835256726183743, "Cerebellar syndrome": 3.1602789768811066, "Cerebral arteriovenous malformation haemorrhagic": 148.2029576147614, "Cerebral disorder": 2.0337845951180418, "Cerebrospinal fluid leakage": 3.124914522970636, "Cervical vertebral fracture": 2.0913302079384315, "Change in seizure presentation": 34.78367373933861, "Cholestasis": 5.181789874253369, "Clavicle fracture": 2.517694702845303, "Cleft lip": 7.464477834214778, "Cleft lip and palate": 12.776725182032406, "Cleft palate": 8.48768246410119, "Clonic convulsion": 2.6581361467549884, "Clonus": 4.078226645786888, "Clumsiness": 3.167213372201454, "Cognitive disorder": 4.142314669844695, "Coma": 2.6703252476594783, "Communication disorder": 3.389334430449012, "Concussion": 3.8566864103780873, "Confusional state": 2.190049230080912, "Congenital central nervous system anomaly": 5.14979451688972, "Congenital foot malformation": 10.298883918096818, "Congenital musculoskeletal disorder": 3.94923095786999, "Congenital musculoskeletal disorder of limbs": 6.049093464150563, "Convulsive threshold lowered": 32.525634297921414, "Coordination abnormal": 3.721878886209749, "Craniocerebral injury": 5.530435129765543, "Craniofacial fracture": 6.768323196800519, "Craniotomy": 11.252890843714871, "Crying": 2.306183885617688, "Cryptorchism": 6.459208641424974, "Daydreaming": 4.344824325148146, "Deja vu": 30.659884840400814, "Delusion": 3.630936393382455, "Depersonalisation/derealisation disorder": 3.326839077110582, "Depressed mood": 3.077349570901074, "Depression": 4.35579355606082, "Depressive symptom": 2.3299272927267687, "Dermatitis exfoliative": 2.302156436116518, "Developmental delay": 5.957345731846353, "Diastolic hypotension": 22.436696982720417, "Diet failure": 173.14810907489195, "Diplopia": 3.1217027153064847, "Disability": 2.727021595603889, "Disinhibition": 2.1517644384008108, "Disorientation": 2.038017173595857, "Disturbance in attention": 2.735240925951926, "Drooling": 3.610613077269485, "Drop attacks": 6.262087241266308, "Drug level below therapeutic": 2.6875317895988244, "Drug level decreased": 4.1597534378370415, "Drug level increased": 2.210521945618221, "Drug reaction with eosinophilia and systemic symptoms": 5.79703559091276, "Drug screen positive": 4.243929569801572, "Drug withdrawal convulsions": 7.363409245311645, "Dysarthria": 2.519768671487279, "Dyschromatopsia": 2.341275909637081, "Dysgraphia": 2.641456722033596, "Dyskinesia": 2.7992603737321464, "Dysmorphism": 4.952210724596361, "Dysphemia": 5.516796096846513, "Dystonia": 2.148328565333581, "Ectopic pregnancy": 2.087263774987293, 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3.491450045099876, "Toxic epidermal necrolysis": 5.79554026742011, "Toxic skin eruption": 2.328553088406141, "Transaminases increased": 2.2023525797378003, "Treatment noncompliance": 3.0214907225936125, "Tumour excision": 6.790339793507255, "Twin pregnancy": 24.059327242550214, "Umbilical cord abnormality": 8.880681574539636, "Umbilical hernia": 2.1114586942217763, "Unevaluable event": 3.6783938439768753, "Unintended pregnancy": 9.37786879798718, "Urinary incontinence": 2.041016616701092, "Urine output increased": 2.76370825029842, "Vagal nerve stimulator implantation": 109.88963584333835, "Ventricular septal defect": 3.4770304811120254, "Volvulus": 2.8328051299593837, "Walking disability": 2.00847525755037, "Weight gain poor": 3.041933541681083, "Wound dehiscence": 7.563922500041955, "Wound infection staphylococcal": 7.834793725380163, "Wrong dose": 6.752981586703715, "Wrong patient": 15.539184202140708, "Wrong patient received product": 6.923945029528878, "Wrong product administered": 2.176759455546631, "Wrong technique in product usage process": 2.19103524317312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/629.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/629.json
index 1f56acaff55..d9e4c4bc414 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/629.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/629.json
@@ -1 +1 @@
-{"Agranulocytosis ": 15.808854883498803, "Condition aggravated ": 4.394074219096827, "Liver injury ": 21.972363966381543, "Off label use ": 3.66364198865929}
\ No newline at end of file
+{"Hyperkalaemia": 100.96397901584324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/63.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/63.json
index c16b5e37649..d67a178cd04 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/63.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/63.json
@@ -1 +1 @@
-{"Ascites ": 3.427845662302708, "Bedridden ": 7.034340330039236, "Blood pressure abnormal ": 5.730729404650674, "Brain natriuretic peptide increased ": 25.95471323723197, "Cardiac arrest ": 2.0899313990081123, "Cardiac disorder ": 2.335791926300617, "Cardiac failure ": 4.728276824691063, "Cardiac failure congestive ": 3.3151349492650053, "Catheter site discharge ": 103.27590703428268, "Cellulitis ": 8.144903209767634, "Crepitations ": 76.48666038426065, "Device occlusion ": 17.347753591515986, "Dizziness exertional ": 209.7620579019165, "Dyspnoea ": 2.7037390777486, "Dyspnoea exertional ": 7.761725619343239, "Epistaxis ": 3.0098741339023487, "Feeding disorder ": 6.791424561786785, "Feeling abnormal ": 2.374010380050143, "Fluid retention ": 15.685837016848804, "Flushing ": 6.205495925250792, "Gastroenteritis viral ": 20.69488058713773, "Haemoptysis ": 3.306428790812638, "Hospitalisation ": 2.973524653144432, "Hypervolaemia ": 17.603873303054794, "Hypoacusis ": 2.7916473154467707, "Hypotension ": 2.117238389579711, "Hypoxia ": 3.4917185393993955, "Ill-defined disorder ": 3.788780259867505, "Illness ": 2.336109502701676, "Infective exacerbation of chronic obstructive airways disease ": 479.62612411042807, "Iron deficiency anaemia ": 16.06189173093725, "Memory impairment ": 2.550416963317032, "Nasal congestion ": 8.602002550380435, "Oedema ": 4.846218519886903, "Oedema peripheral ": 5.576157889574819, "Oxygen saturation decreased ": 3.533498342552415, "Pain in jaw ": 20.35193601894708, "Pericardial effusion ": 4.064654600447698, "Peripheral swelling ": 2.21963515297341, "Premature delivery ": 6.1744054254780325, "Productive cough ": 10.476618575923926, "Pulmonary arterial hypertension ": 31.80249356509378, "Pulmonary hypertension ": 23.393007946377143, "Pulmonary oedema ": 2.9655075655627914, "Right ventricular failure ": 55.299270670161874, "Skin discolouration ": 2.4693956830556747, "Transfusion ": 10.481514586680497, "Unevaluable event ": 7.399869150646448, "Vascular device infection ": 34.23346945907328, "Vitamin D decreased ": 24.229767969928343, "Weight decreased ": 2.920628145350486, "Weight increased ": 3.97229738675915, "Wheezing ": 2.1237616544143507}
\ No newline at end of file
+{"Syncope": 4.986048457054526}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/630.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/630.json
index 3d1b7cbc0ca..1c1978ca56d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/630.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/630.json
@@ -1 +1 @@
-{"Cough ": 5.544821491995517}
\ No newline at end of file
+{"Abortion spontaneous": 2.745017414611656, "Acne": 3.275654601448426, "Alopecia": 2.168174005122785, "B-lymphocyte count decreased": 284.462427783172, "Blood immunoglobulin G decreased": 47.53312550050819, "Blood immunoglobulin M decreased": 222.44735195869603, "Body temperature increased": 4.055517813646709, "Brain fog": 2.0216948139048894, "Breast cancer": 2.3297094260879407, "Bronchitis": 2.3470476864614547, "Central nervous system lesion": 14.729543421403823, "Coronavirus infection": 38.14334658421333, "Cystitis noninfective": 32.19185824680456, "Disease recurrence": 4.121766049866988, "Gait disturbance": 3.784354349650391, "Hemiparesis": 4.337666077675605, "Hypoaesthesia": 2.9636502819010446, "Incorrect dose administered by device": 8.448579496906097, "Infection": 3.3217266954155638, "Influenza": 2.7477400831620264, "Influenza like illness": 6.522479623162985, "Injection related reaction": 41.89252635681664, "Injection site haemorrhage": 5.423620175613192, "Listless": 4.753311765503098, "Liver function test increased": 2.489360719050035, "Lymphocyte count decreased": 29.657195624357826, "Lymphopenia": 9.54347259262302, "Maternal exposure during breast feeding": 4.468809395352782, "Multiple sclerosis": 50.33137836897392, "Multiple sclerosis relapse": 86.02330080684595, "Muscle spasticity": 8.92738570125401, "Muscular weakness": 2.325459609638912, "Nasopharyngitis": 8.460833075355314, "Optic neuritis": 10.21881080861654, "Oral herpes": 9.870295650029282, "Oropharyngeal pain": 3.124306366718031, "Paralysis": 2.623151903764049, "Relapsing-remitting multiple sclerosis": 141.534833756436, "Respiratory tract infection": 3.871728013760523, "Rhinorrhoea": 3.2106796698796525, "SARS-CoV-2 test positive": 5.556937183258048, "Secondary progressive multiple sclerosis": 100.80460411597666, "Sensory disturbance": 3.839782968214692, "Throat irritation": 2.211219098823108, "Upper respiratory tract infection": 2.434798065387689, "Urinary tract infection": 3.3011410479889527}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/631.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/631.json
index 6a5c9af970a..93961265224 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/631.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/631.json
@@ -1 +1 @@
-{"Dyspnoea ": 2.164032281173917}
\ No newline at end of file
+{"Off label use": 9.39903848808776}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/632.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/632.json
index e4d90e870bc..b6705afed8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/632.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/632.json
@@ -1 +1 @@
-{"Anaphylactic reaction ": 5.221294284930504, "Anaphylactic shock ": 3.8399960865024623, "Anaphylactoid reaction ": 17.596572886453956, "Back pain ": 3.731648370017065, "Blood pressure increased ": 3.046015383938677, "Body temperature increased ": 5.35426907012695, "Bronchospasm ": 3.6483714107038696, "Chest discomfort ": 2.290970881067411, "Chills ": 4.4110875423212565, "Cyanosis ": 11.3570530146945, "Drug intolerance ": 3.006177503677002, "Dyspnoea ": 2.3310153714229425, "Erythema ": 2.8047878372077237, "Exposure during pregnancy ": 4.758072862278105, "Feeling cold ": 3.387153975982057, "Flushing ": 5.503629325473761, "Foetal exposure during pregnancy ": 2.153870562547876, "Haemolysis ": 40.068465592741504, "Haemolytic anaemia ": 15.936833509753832, "Hepatitis B core antibody positive ": 119.908424629118, "Hypersensitivity ": 3.9186072475493634, "Hypertension ": 2.829039417747619, "Hyperthermia ": 15.947944483501754, "Hypotension ": 2.3293045649874595, "Hypoxia ": 2.669461542959915, "Infusion related reaction ": 6.4666658005341136, "Livedo reticularis ": 60.54969248978288, "Meningitis ": 12.883176172319638, "Meningitis aseptic ": 120.66271390629689, "Oxygen saturation decreased ": 8.142419989866568, "Pallor ": 3.765455318282479, "Peripheral coldness ": 3.158261590466468, "Photophobia ": 2.932849149058149, "Premature baby ": 3.379669654386116, "Premature delivery ": 5.436984145381256, "Respiratory distress ": 3.415195640407385, "Tachycardia ": 4.515838472941581, "Tachypnoea ": 6.077481772494963, "Tremor ": 3.2911689158927584, "Urticaria ": 2.775070812125989, "Vomiting ": 2.1006608148745363}
\ No newline at end of file
+{"Alanine aminotransferase increased": 4.355758747178736, "Aspartate aminotransferase increased": 5.515641905804967, "Chromaturia": 14.048979455581048, "Drug interaction": 4.77327077947787, "Drug-induced liver injury": 7.214179197261425, "Hepatic enzyme increased": 4.112390649915261, "International normalised ratio increased": 14.554849425650922, "Jaundice": 13.372204526990384}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/633.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/633.json
index 84ccc4b962a..64f9978e58c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/633.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/633.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 8.697353359952956, "Alopecia ": 3.0801741479401343, "Anaemia ": 2.0365977363857657, "Aphthous ulcer ": 2.5346160377874063, "Aspartate aminotransferase increased ": 9.53093687269678, "Autoimmune hepatitis ": 4.662140448474119, "Blood alkaline phosphatase increased ": 3.525878313786228, "Blood bilirubin increased ": 5.722674809795118, "Blood creatinine increased ": 2.1884418505127563, "Blood test abnormal ": 3.143046533979188, "Bone pain ": 2.0384641392787737, "Breast cancer ": 12.82799912393435, "Breast cancer metastatic ": 49.261672259770044, "Breast cancer recurrent ": 21.115083688579197, "Breast mass ": 5.230897797688006, "Carbohydrate antigen 15-3 increased ": 43.474940418134246, "Carcinoembryonic antigen increased ": 16.59629328567184, "Cell death ": 11.223199500063604, "Decreased immune responsiveness ": 22.14361000558108, "Disease progression ": 3.0846933067524125, "Dry skin ": 6.189108316200277, "Eating disorder ": 2.374733127119992, "Electrocardiogram QT prolonged ": 34.01419135788273, "Gamma-glutamyltransferase increased ": 4.02842079859986, "Gastritis ": 2.2851938233121345, "Glomerular filtration rate decreased ": 2.372394845257269, "Granulocytopenia ": 3.364686094082049, "Haematocrit decreased ": 5.334721197358444, "Haematotoxicity ": 9.52389482859843, "Haemoglobin decreased ": 2.735794503153165, "Hepatic cytolysis ": 8.661838990026082, "Hepatic enzyme increased ": 5.272050677932922, "Hepatic lesion ": 8.380137348698895, "Hepatitis ": 3.111126885078716, "Hepatitis acute ": 3.785607562912243, "Hepatocellular injury ": 3.399987723554554, "Hepatotoxicity ": 31.71551463656383, "Hormone receptor positive HER2 negative breast cancer ": 127.9005657796427, "Hypertransaminasaemia ": 18.154727766307488, "Hypocalcaemia ": 2.4715232658730213, "Immunodeficiency ": 2.7072478251412746, "Jaundice ": 2.493529651810884, "Laboratory test abnormal ": 3.828933922779064, "Lacrimation increased ": 4.072918278244662, "Leukopenia ": 10.860752295209371, "Liver function test abnormal ": 4.145631872372797, "Liver function test increased ": 15.37090083488622, "Lymphocyte count decreased ": 4.53511348170126, "Madarosis ": 18.426697040160583, "Malignant neoplasm progression ": 11.123173098770913, "Metastases to bone ": 37.6961749525868, "Metastases to central nervous system ": 6.32742206755942, "Metastases to liver ": 15.010978097019722, "Metastases to lung ": 16.481581218461102, "Metastases to lymph nodes ": 10.127196207173396, "Metastases to spine ": 35.82018120446954, "Metastasis ": 26.336611257910043, "Mucosal inflammation ": 2.0309088798652577, "Neoplasm ": 4.562013437372067, "Neutropenia ": 31.284378028615265, "Neutrophil count abnormal ": 14.151957148948668, "Neutrophil count decreased ": 6.248092525057419, "Pancytopenia ": 2.684617507136792, "Pigmentation disorder ": 5.251146733616541, "Pleural effusion ": 3.0428501860148667, "Pneumonitis ": 10.406482214027596, "Pulmonary mass ": 2.3870699690185435, "Red blood cell count decreased ": 2.487172250706836, "Second primary malignancy ": 4.840285452898643, "Skin exfoliation ": 3.8624027475706058, "Skin reaction ": 2.3447665588577515, "Skin toxicity ": 7.609922004740166, "Spinal pain ": 3.1869202919652992, "Therapy partial responder ": 7.451667199649868, "Thrombocytopenia ": 2.142224000450723, "Transaminases increased ": 10.33776487715143, "Tumour marker increased ": 25.20782291049756, "Vitiligo ": 35.761569876368, "White blood cell count decreased ": 5.314712591094712}
\ No newline at end of file
+{"Abdominal distension": 3.0062006333038283, "Bladder dilatation": 199.8597747404807, "Blood pressure increased": 2.813828948844818, "Constipation": 2.058027656312107, "Disease progression": 4.512879104731893, "Drug interaction": 5.277654561802356, "Electrocardiogram QT prolonged": 4.789970606935725, "Heart rate increased": 2.483794224687885, "Hypersensitivity": 2.6482454269344577, "Hypertonia": 29.58478134540618, "Muscle tightness": 16.48986926511455, "Musculoskeletal stiffness": 2.535045555170216, "Oedema peripheral": 2.7535401128532278, "Performance status decreased": 30.796717521955948, "Respiratory distress": 5.883485711525176, "Restlessness": 4.638658723211905, "Subcutaneous abscess": 74.53458561849743, "Therapy non-responder": 12.924946882997167, "Urinary incontinence": 9.487403754425392, "Urinary retention": 4.849656710869163}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/634.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/634.json
index 7baab054649..ad86d2b925e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/634.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/634.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 8.495009555188792, "Blood bilirubin increased ": 3.808926616883882, "Blood creatinine increased ": 2.252735372748044, "Cholelithiasis ": 7.463124612674903, "Drug reaction with eosinophilia and systemic symptoms ": 4.263325949771924, "Eosinophilia ": 5.088487823700116, "Exposure during pregnancy ": 6.178409151584386, "Faecaloma ": 34.57568742409237, "Foetal exposure during pregnancy ": 4.451475981750538, "Foetal growth restriction ": 30.626395538135064, "Gamma-glutamyltransferase increased ": 4.525833059178416, "Gastrointestinal disorder ": 2.9624545263051005, "Hepatic cytolysis ": 11.390235639115737, "Hepatitis ": 4.221094782526648, "Hyperbilirubinaemia ": 18.051900573636303, "Jaundice ": 6.632792584050142, "Live birth ": 28.074936511916107, "Myocardial infarction ": 3.8757845799855386, "Nephrolithiasis ": 13.422247823597411, "Osteoarthritis ": 4.465408946100279, "Osteoporosis ": 2.5657577985167404, "Pancreatitis acute ": 3.981455186552933, "Rash maculo-papular ": 2.5458236966590846, "Renal colic ": 40.01624325571736, "Sleep disorder ": 2.7056596780610738, "Toxic epidermal necrolysis ": 7.03745897433159, "Transaminases increased ": 8.521558591341996, "Tubulointerstitial nephritis ": 13.321725348363682}
\ No newline at end of file
+{"Joint swelling": 5.997879029756566, "Rheumatoid arthritis": 11.266127632936591}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/635.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/635.json
index 716832f7036..f51a69ba9d0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/635.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/635.json
@@ -1 +1 @@
-{"Anti factor VIII antibody positive ": 3799.027533412679, "Anti factor VIII antibody test ": 4233.530740644854, "Drug specific antibody ": 316.4478466455078, "Factor VIII inhibition ": 2221.579916647552, "Haemarthrosis ": 316.6545819566622, "Haemorrhage ": 41.95756806455338, "Inhibiting antibodies ": 5583.317080444805}
\ No newline at end of file
+{"Acute interstitial pneumonitis": 5.9858941016063465, "Acute polyneuropathy": 5.423642573173516, "Addison's disease": 6.863777668511075, "Administration site extravasation": 2.963205752341145, "Adrenal disorder": 37.4055659305814, "Adrenal insufficiency": 49.96132410392669, "Adrenocortical insufficiency acute": 16.49358859672793, "Adrenocorticotropic hormone deficiency": 104.72980729757236, "Adverse event": 12.32662067913909, "Alanine aminotransferase abnormal": 2.048460936959471, "Amylase increased": 4.406260090593412, "Aortic arteriosclerosis": 2.5023006778686496, "Aortitis": 3.1344817389793667, "Ascites": 2.281806779520439, "Aspartate aminotransferase abnormal": 4.529578160979906, "Atelectasis": 2.7484267593507123, "Atrioventricular block complete": 2.070340600984403, "Autoimmune arthritis": 32.68322652261469, "Autoimmune colitis": 37.19449774509005, "Autoimmune haemolytic anaemia": 6.385255743966497, "Autoimmune hepatitis": 14.567260185171154, "Autoimmune hypothyroidism": 47.03340135876147, "Autoimmune lung disease": 45.09308897844004, "Autoimmune myocarditis": 71.32512663918172, "Autoimmune myositis": 26.656553489654563, "Autoimmune nephritis": 31.256939090683133, "Autoimmune pancreatitis": 37.8769781378934, "Autoimmune thyroiditis": 7.639380350609758, "Bladder tamponade": 9.257874352443771, "Blood albumin decreased": 2.2711219128517586, "Blood alkaline phosphatase abnormal": 5.584270196631741, "Blood bilirubin abnormal": 3.345651308848639, "Blood corticotrophin abnormal": 23.01939993595458, "Blood corticotrophin decreased": 32.04472163339069, "Blood corticotrophin increased": 31.932085518528627, "Blood creatine phosphokinase MB increased": 2.08882233605587, "Blood creatinine abnormal": 3.5339809094165315, "Blood creatinine decreased": 2.8284502325846046, "Blood sodium decreased": 2.344010833982826, "Blood thyroid stimulating hormone abnormal": 9.80867037062944, "Blood thyroid stimulating hormone decreased": 11.615835547584544, "Blood thyroid stimulating hormone increased": 13.781375562862314, "Brain natriuretic peptide increased": 2.2493072929339464, "Brain oedema": 2.31691538115578, "Breast conserving surgery": 2.5209981571738136, "C-reactive protein increased": 2.1702013637384403, "Cancer pain": 12.033635106357544, "Cancer surgery": 11.257764479518537, "Capillary leak syndrome": 2.565137337670306, "Carbohydrate antigen 125 increased": 2.618085061259877, "Carcinoembryonic antigen increased": 3.885127382447534, "Cardiac dysfunction": 4.289507000475235, "Cardiac failure acute": 2.6856154176545903, "Cardiac tamponade": 7.992303099230582, "Cardiomyopathy": 2.022811556109173, "Central hypothyroidism": 15.64901358126814, "Central venous catheterisation": 5.071430058306771, "Cerebral infarction": 2.015942754939496, "Cheilitis": 2.0514852323936563, "Chemotherapy": 5.386842558262338, "Cholangitis": 12.698527566623104, "Cholangitis acute": 4.793426084449924, "Cholangitis sclerosing": 59.75450838583468, "Cholecystitis": 5.822007725459072, "Cholecystitis acute": 5.795381278207016, "Cholestatic liver injury": 2.3967148765540047, "Chronic gastritis": 2.1284898644016685, "Colitis": 13.857092327317469, "Colitis microscopic": 3.859844385147076, "Coronavirus infection": 3.495616055618497, "Cortisol abnormal": 22.799451017272897, "Cortisol decreased": 17.02096377466439, "Cortisol increased": 8.853636890922294, "Cutaneous sarcoidosis": 5.050868227443964, "Cutaneous symptom": 3.743459729134848, "Cytokine release syndrome": 2.5720050915571866, "Cytokine storm": 13.275480015917, "Cytomegalovirus enterocolitis": 6.346391971092817, "Cytopenia": 2.2101440765197244, "Death": 2.97659342580551, "Decreased appetite": 2.746040012483988, "Demyelinating polyneuropathy": 2.5635712512294084, "Dermatitis": 2.192279299806754, "Dermatitis psoriasiform": 7.0738523044524655, "Dermatomyositis": 8.576905071653554, "Device related infection": 2.690611084579405, "Diabetes mellitus": 2.043063787330761, "Diabetic ketoacidosis": 3.359872781936551, "Diabetic ketosis": 3.270498827914873, "Disseminated intravascular coagulation": 3.681410023653378, "Drug effective for unapproved indication": 4.970677027113952, "Drug eruption": 2.735170833177791, "Drug-induced liver injury": 2.516676522645352, "Duodenal perforation": 9.332353723677937, "Duodenal ulcer": 2.498005101281809, "Duodenitis": 2.726024683281772, "Dysphonia": 4.05114417636358, "Eastern Cooperative Oncology Group performance status worsened": 56.97268525496919, "Electrolyte imbalance": 2.2884304236310617, "Encephalitis": 11.08818906213535, "Encephalitis autoimmune": 18.750212506874764, "Endocrine disorder": 9.52534947040808, "Enteritis": 4.84549699662537, "Enteritis infectious": 3.897537586337428, "Enterocolitis": 16.60791368311092, "Enterocolitis haemorrhagic": 2.117081288607134, "Eosinophil count increased": 2.956843160119042, "Eosinophil percentage increased": 6.684185973198688, "Eosinophilic fasciitis": 13.064842871226915, "Erythema multiforme": 4.452435183333456, "Eyelid ptosis": 6.5228979283145625, "Febrile bone marrow aplasia": 4.057648691568108, "Febrile neutropenia": 2.8079043119371896, "Feeding disorder": 2.406856074628886, "Female genital tract fistula": 2.490888177887532, "Fistula": 4.291762525529296, "Fulminant type 1 diabetes mellitus": 117.98497221773302, "Gallbladder enlargement": 2.3226943086584, "Gamma-glutamyltransferase abnormal": 4.863051866913594, "Gastric perforation": 3.3626584490213767, "Gastrointestinal oedema": 4.802679667081652, "Gastrointestinal perforation": 10.034904563258438, "Gingivitis": 2.084454227897091, "Glomerulonephritis membranous": 3.1838216115646825, "Glomerulonephritis rapidly progressive": 5.414875226241813, "Glucocorticoid deficiency": 29.365829221533048, "Graves' disease": 2.1509895546126616, "Guillain-Barre syndrome": 3.184928289240782, "Haemoglobin abnormal": 4.161181808450198, "Haemophagocytic lymphohistiocytosis": 8.293215613179738, "Hepatic cytolysis": 2.5012765721207058, "Hepatic function abnormal": 4.693654877376465, "Hepatitis": 6.661270612987801, "Hepatitis fulminant": 2.54636020010749, "Hepatotoxicity": 2.2208908734053985, "Hospice care": 11.290984229118711, "Hydronephrosis": 4.033669715805142, "Hyperamylasaemia": 4.407495560311134, "Hyperlipasaemia": 3.040108898540009, "Hypertension": 3.839077640973604, "Hyperthyroidism": 16.50293212683646, "Hypertransaminasaemia": 2.32853674668975, "Hypoalbuminaemia": 3.1699979924105604, "Hypophysitis": 39.63700463116541, "Hypopituitarism": 53.13167654906784, "Hypothalamo-pituitary disorder": 33.389316598495235, "Hypothyroidism": 32.009073399516225, "Ileus": 3.391501897468668, "Immune thrombocytopenia": 5.552863011836945, "Immune-mediated adrenal insufficiency": 259.55995157599045, "Immune-mediated adverse reaction": 106.52381131281108, "Immune-mediated arthritis": 134.23657725866886, "Immune-mediated cholangitis": 360.8859773064907, "Immune-mediated cystitis": 82.34998384098816, "Immune-mediated dermatitis": 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3.476965025956206, "Loss of therapeutic response": 2.2155471670500693, "Lung abscess": 4.362993419929228, "Lung carcinoma cell type unspecified recurrent": 6.749178632115048, "Lung consolidation": 2.347179022607832, "Lung disorder": 3.413939138167724, "Lung opacity": 7.04647066693587, "Lymphadenectomy": 10.28188284423604, "Lymphadenopathy mediastinal": 3.9611418075168223, "Lymphangiosis carcinomatosa": 17.719233578948494, "Lymphocytic hypophysitis": 15.217136936711006, "Malignant ascites": 15.440631322205238, "Malignant gastrointestinal obstruction": 40.064834907249406, "Malignant neoplasm oligoprogression": 42.1456158954154, "Malignant neoplasm progression": 34.96822773017049, "Malignant pleural effusion": 16.600211251913457, "Mastectomy": 3.403520599257982, "Mean cell haemoglobin increased": 3.238842142071366, "Melanoma recurrent": 19.44133504356189, "Meningitis": 4.86887302980892, "Meningitis aseptic": 2.4619659063791017, "Metastases to meninges": 3.7097167425074993, "Metastatic malignant melanoma": 2.8985133271412504, "Mixed liver injury": 2.3153048705286348, "Mucosal inflammation": 2.7286258499253355, "Myasthenia gravis": 29.30410881728257, "Myasthenia gravis crisis": 9.84456060748407, "Myasthenic syndrome": 15.889813851521874, "Myelosuppression": 2.060593526899936, "Myocardial necrosis marker increased": 3.077537087033547, "Myocarditis": 6.14896135494254, "Myositis": 20.54627431368768, "Necrotising fasciitis": 2.362357341166491, "Necrotising myositis": 15.26776937104628, "Nephritis": 33.226557355843035, "Nephrotic syndrome": 3.1503311454662084, "Neuromyopathy": 2.317896217044717, "Neuropathy peripheral": 2.544650218247765, "Neutrophil count decreased": 2.8420731083858897, "Non-small cell lung cancer recurrent": 16.986529660325093, "Nutritional condition abnormal": 5.222949048736446, "Ocular myasthenia": 11.79291697130396, "Oesophageal perforation": 6.376508759587331, "Oesophageal stenosis": 3.139014918535141, "Ophthalmoplegia": 2.556990051022161, "Optic neuritis": 3.2575266224668007, "Oral mucosa erosion": 2.842132659033052, "Organising pneumonia": 15.58134444401968, "Oxygen saturation abnormal": 3.268165081972396, "Oxygen therapy": 4.168574062993439, "Palliative care": 6.598778109954676, "Palmar-plantar erythrodysaesthesia syndrome": 8.739346426999743, "Pancreatic enzymes increased": 2.741945148844525, "Pancreatic failure": 3.436141387702192, "Paraneoplastic syndrome": 12.31315374124585, "Pathological fracture": 2.0493725158764, "Pemphigoid": 13.812657903100506, "Perforation": 8.080046018362172, "Pericardial effusion": 3.4180337757759487, "Pericarditis malignant": 96.006769445434, "Physical deconditioning": 3.06148137571326, "Platelet count decreased": 4.40744973126997, "Pleural effusion": 3.798437415954981, "Pneumatosis intestinalis": 3.60293607173554, "Pneumocystis jirovecii pneumonia": 4.05608732474853, "Pneumonia": 2.158635055427426, "Pneumonia aspiration": 3.532247897940661, "Pneumonia bacterial": 9.302766115684337, "Pneumonitis": 23.00530411361578, "Pneumothorax": 4.381437393337777, "Polyarthritis": 6.084948471745283, "Polymyalgia rheumatica": 6.8237841610258725, "Polymyositis": 8.695178745054756, "Posterior reversible encephalopathy syndrome": 2.826767572844566, "Postrenal failure": 11.61807519733189, "Prerenal failure": 5.64994917623906, "Primary adrenal insufficiency": 18.042306701863144, "Primary hypothyroidism": 14.763028292554106, "Procalcitonin increased": 4.277397947222581, "Product use in unapproved indication": 5.992439118742416, "Product use issue": 2.9232091585348856, "Protein urine": 13.279468739183656, "Protein urine present": 3.671621383980899, "Proteinuria": 13.23385737812034, "Psoas abscess": 4.57827698607372, "Pulmonary sarcoidosis": 6.5257167053251335, "Pulmonary toxicity": 9.430856986995682, "Pyelonephritis": 2.8259934171817886, "Radiation injury": 6.785229501095956, "Radiation pneumonitis": 32.06996900287799, "Radiotherapy": 21.861577801103493, "Rectal perforation": 10.672636963476972, "Recurrent cancer": 8.020189305006207, "Red blood cell count abnormal": 3.7391436938121454, "Red blood cell count increased": 2.2000650695922754, "Red blood cell transfusion": 4.1600996866476585, "Renal impairment": 3.271265615443201, "Renal tubular acidosis": 2.5977353359869477, "Respiratory failure": 2.0183076658759225, "Retroperitoneal fibrosis": 5.4751955530122345, "Rheumatic disorder": 2.1512294188501757, "Salivary hyposecretion": 4.113838819314536, "Sarcoidosis": 4.183221851282167, "Secondary adrenocortical insufficiency": 34.77567618464951, "Septic shock": 2.771219958274058, "Seronegative arthritis": 3.897537586337428, "Sialoadenitis": 6.63841663321051, "Silent thyroiditis": 63.5994119558334, "Sjogren's syndrome": 6.088754211896188, "Skin disorder": 3.933002022258534, "Skin toxicity": 6.79551368060786, "Small intestinal haemorrhage": 2.9413889644352835, "Small intestinal perforation": 20.73023046514844, "Stevens-Johnson syndrome": 3.947125338065236, "Stomatitis": 4.1680013108869005, "Stress cardiomyopathy": 3.0529286493478844, "Subacute cutaneous lupus erythematosus": 3.0472870298527583, "Superior vena cava syndrome": 5.811338842542092, "Therapeutic response increased": 2.2962881443385816, "Therapy partial responder": 15.826966533671126, "Thrombophlebitis migrans": 46.01875719887684, "Thyroid disorder": 11.238894508797744, "Thyroid function test abnormal": 5.692518775649711, "Thyroid hormones decreased": 14.119896063107138, "Thyroid hormones increased": 8.041047766133515, "Thyroiditis": 39.6945164565048, "Thyroiditis subacute": 2.6348635511817737, "Thyrotoxic crisis": 9.139658411819342, "Thyroxine free decreased": 5.20156290134426, "Thyroxine free increased": 6.189140376749272, "Toxic epidermal necrolysis": 3.4437704613405997, "Transfusion": 2.2354147062818197, "Tri-iodothyronine free decreased": 18.203958342709377, "Tri-iodothyronine free increased": 18.722171113477295, "Troponin I increased": 2.9040463898065627, "Troponin T increased": 3.580594670105923, "Troponin increased": 4.445705566910278, "Tubulointerstitial nephritis": 10.747595778394777, "Tumour associated fever": 51.05890673166939, "Tumour haemorrhage": 7.391472663156597, "Tumour hyperprogression": 100.92984645958352, "Tumour lysis syndrome": 3.019872986768747, "Tumour marker increased": 3.551526849782026, "Tumour necrosis": 15.666612343451034, "Tumour pain": 6.875913257159721, "Tumour pseudoprogression": 81.37588099223142, "Type 1 diabetes mellitus": 34.40994460448309, "Urogenital fistula": 37.38764055173478, "Uveitis": 4.246042284750102, "Vitiligo": 19.697940508085768, "Vocal cord paralysis": 2.094980583399076, "Vogt-Koyanagi-Harada disease": 9.601524784091437, "Warm autoimmune haemolytic anaemia": 14.567172774168831}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/636.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/636.json
index ae71afe0abc..4bade17e691 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/636.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/636.json
@@ -1 +1 @@
-{"Blister ": 74.64098888771214, "Genital erosion ": 10901.437672281838, "Mucosal erosion ": 3914.518092932005, "Rash ": 10.878251681665288, "Stevens-Johnson syndrome ": 241.22462686802143, "Toxic epidermal necrolysis ": 240.08497729088683}
\ No newline at end of file
+{"Agranulocytosis": 15.808854883498803, "Condition aggravated": 4.394074219096827, "Liver injury": 21.972363966381543, "Off label use": 3.6634976952605465}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/637.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/637.json
index 9f6d685b982..ed312b0780e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/637.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/637.json
@@ -1 +1 @@
-{"Anti factor VIII antibody positive ": 1329.062886870339, "Contusion ": 7.802982581547032, "Epistaxis ": 5.478776902851115, "Fall ": 3.630810348530372, "Haemarthrosis ": 1441.2948583006842, "Haemorrhage ": 103.14428869768828, "Joint injury ": 67.81377526866912, "Joint swelling ": 4.475144717503885, "Limb injury ": 63.36811877106136, "Muscle haemorrhage ": 231.06293822332853, "Peripheral swelling ": 2.661680718730477, "Product dose omission issue ": 2.3884121023472304, "Traumatic haemorrhage ": 891.2060412906651}
\ No newline at end of file
+{"Cough": 5.544770067809691}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/638.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/638.json
index d5a9ea13055..c960efacd10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/638.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/638.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 19.63690358637492, "Aggression ": 4.067437477392114, "Amino acid level increased ": 2041.1466107797487, "Anaphylactic reaction ": 4.3307456980514765, "Anxiety ": 2.212205437105592, "Depression ": 4.440819536219736, "Exposure during pregnancy ": 3.4241582567129507, "Gastrooesophageal reflux disease ": 3.1855983746183605, "Maternal exposure during pregnancy ": 14.039416233340251, "Premature baby ": 8.506722303138876, "Seizure ": 4.2155182319025855, "Therapy non-responder ": 8.788457364335828, "Throat tightness ": 7.929692773991227}
\ No newline at end of file
+{"Dyspnoea": 2.164000133484996}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/639.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/639.json
index f7d977f5446..b93a8722bb5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/639.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/639.json
@@ -1 +1 @@
-{"Activated partial thromboplastin time prolonged ": 11.55304010966129, "Acute graft versus host disease in skin ": 6.362211731247109, "Acute lymphocytic leukaemia ": 90.54376377264838, "Acute lymphocytic leukaemia recurrent ": 584.0499794171417, "Acute lymphocytic leukaemia refractory ": 132.35339382448248, "Aphasia ": 3.975692058042827, "Apraxia ": 11.735727412449387, "Atelectasis ": 4.00220821779747, "B precursor type acute leukaemia ": 80.35453078541197, "B-cell aplasia ": 3400.4029704541445, "B-cell type acute leukaemia ": 203.59502564334872, "B-lymphocyte count abnormal ": 1929.585872279043, "Bacteraemia ": 4.141837613329832, "Blast cell count increased ": 86.52630852031776, "Blood albumin decreased ": 7.287499776215023, "Blood calcium decreased ": 5.421222115419543, "Blood chloride increased ": 10.89032492788458, "Blood fibrinogen decreased ": 66.71422532841393, "Blood fibrinogen increased ": 50.14012708155608, "Blood lactate dehydrogenase increased ": 6.22835359434703, "Blood phosphorus decreased ": 7.981567287742407, "Blood potassium decreased ": 3.0609553439728923, "Blood pressure systolic decreased ": 5.956464603966593, "Bone lesion ": 14.103931280489345, "Bone marrow disorder ": 11.097710664018605, "Bone marrow failure ": 6.96689146524679, "Brain oedema ": 3.950546775118291, "C-reactive protein decreased ": 31.558231966858525, "C-reactive protein increased ": 6.127000129911542, "Capillary leak syndrome ": 25.71118295925762, "Carbon dioxide decreased ": 21.223514497999616, "Central nervous system leukaemia ": 89.18146417743372, "Central nervous system lymphoma ": 26.42000969427001, "Clostridium difficile colitis ": 5.132989245704502, "Coagulopathy ": 18.811886412506823, "Congenital aplasia ": 10.052785113625568, "Cytokine release syndrome ": 586.2176351714313, "Cytokine storm ": 35.87193091251117, "Cytomegalovirus infection ": 3.52619971716912, "Cytopenia ": 29.985330289574986, "Diffuse large B-cell lymphoma ": 281.69919468589995, "Diffuse large B-cell lymphoma recurrent ": 376.9993592030765, "Diffuse large B-cell lymphoma refractory ": 125.3572413811146, "Disease progression ": 2.1319660540186987, "Disease recurrence ": 4.768185422539154, "Disorientation ": 3.627609349416739, "Disseminated intravascular coagulation ": 4.148602777615936, "Dysgraphia ": 11.160270710439791, "Electrolyte imbalance ": 2.997902569153828, "Encephalopathy ": 6.515280847963993, "Enterococcal infection ": 13.595702756095022, "Febrile neutropenia ": 3.787204974713673, "Fibrin D dimer increased ": 5.915109796147887, "Full blood count decreased ": 11.05449778336716, "Graft versus host disease ": 3.204861424632776, "Haematocrit decreased ": 4.583176079809899, "Haemodynamic instability ": 3.1639243104934165, "Haemoglobin decreased ": 2.856055594230809, "Haemophagocytic lymphohistiocytosis ": 39.15127894587606, "Hepatomegaly ": 3.8070722932632046, "Hypervolaemia ": 8.987968137474015, "Hypofibrinogenaemia ": 57.89219235225119, "Hypogammaglobulinaemia ": 140.2758781423761, "Hypotension ": 6.107060095982347, "Hypoxia ": 16.491645778492636, "Immune effector cell-associated neurotoxicity syndrome ": 442.8114166519695, "Incontinence ": 2.358406836584282, "Inflammatory marker increased ": 7.161187893129215, "Interleukin level increased ": 125.56499856297658, "Intracranial pressure increased ": 3.5156190512935344, "Left ventricular dysfunction ": 6.337394284218184, "Leukaemia recurrent ": 10.81243580264405, "Localised oedema ": 2.921036106234984, "Loss of CAR T-cell persistence ": 1719.9631390808895, "Lymphocyte count decreased ": 22.333219464869316, "Lymphoma ": 7.175316025947196, "Lymphopenia ": 2.6902697229658705, "Malignant neoplasm progression ": 16.231291541400513, "Mean cell haemoglobin concentration increased ": 63.47993213053206, "Mental status changes ": 5.526766816122155, "Metastases to central nervous system ": 2.8065009163255565, "Metastases to meninges ": 17.4087257488375, "Minimal residual disease ": 403.7936048847712, "Multiple organ dysfunction syndrome ": 5.148071230720524, "Myelodysplastic syndrome ": 5.44973197528824, "Nervous system disorder ": 6.08858583728322, "Neurological decompensation ": 19.10260970130401, "Neurotoxicity ": 66.64143421379781, "Neutropenia ": 2.934549689507614, "Neutrophil count decreased ": 4.987939989390185, "Non-Hodgkin's lymphoma ": 8.82161451713208, "Oliguria ": 4.218055009751324, "Optic neuritis ": 2.4056935949643994, "Out of specification test results ": 994.662270761931, "Oxygen saturation decreased ": 3.0504200676910527, "Pancytopenia ": 6.835060632109216, "Platelet count decreased ": 4.198761806161137, "Pleural effusion ": 2.065617109154086, "Pneumonia fungal ": 7.032640355274652, "Post-depletion B-cell recovery ": 14899.032451876572, "Protein total decreased ": 9.225437549353147, "Prothrombin time prolonged ": 7.042070123370153, "Pyrexia ": 2.615402906920072, "Red blood cell count decreased ": 5.592592327324308, "Red cell distribution width increased ": 9.114433446266275, "Remission not achieved ": 95.7618000705373, "Respiratory rate increased ": 3.822219750053017, "Second primary malignancy ": 20.21401009052694, "Septic shock ": 3.3417569749010974, "Serum ferritin increased ": 65.39416401357049, "T-cell lymphoma ": 33.08506731837743, "Tachycardia ": 2.503902500181681, "Tachypnoea ": 7.78723374135085, "Therapeutic product effect incomplete ": 4.7445036753695, "Therapy non-responder ": 5.525898789947751, "Therapy partial responder ": 4.801821557044752, "Thrombocytopenia ": 2.279121147127703, "Transformation to acute myeloid leukaemia ": 77.33313869724412, "Tumour lysis syndrome ": 10.239030383835916, "White blood cell count decreased ": 2.96821724130266, "White blood cell count increased ": 2.6052933391243687}
\ No newline at end of file
+{"Anaphylactic reaction": 5.22118317497265, "Anaphylactic shock": 3.8399960865024623, "Anaphylactoid reaction": 17.596572886453956, "Back pain": 3.731648370017065, "Blood pressure increased": 3.0459618838846807, "Body temperature increased": 5.35426907012695, "Bronchospasm": 3.6483714107038696, "Chest discomfort": 2.2908904338571543, "Chills": 4.411073982401055, "Cyanosis": 11.354928345991318, "Drug intolerance": 3.006177503677002, "Dyspnoea": 2.3309807196860257, "Erythema": 2.8047603844542133, "Exposure during pregnancy": 4.758072862278105, "Feeling cold": 3.387153975982057, "Flushing": 5.503629325473761, "Foetal exposure during pregnancy": 2.153870562547876, "Haemolysis": 40.068465592741504, "Haemolytic anaemia": 15.936833509753832, "Hepatitis B core antibody positive": 119.908424629118, "Hypersensitivity": 3.9186072475493634, "Hypertension": 2.829010191714663, "Hyperthermia": 15.947944483501754, "Hypotension": 2.3292506860319104, "Hypoxia": 2.669461542959915, "Infusion related reaction": 6.4666658005341136, "Livedo reticularis": 60.54969248978288, "Meningitis": 12.883176172319638, "Meningitis aseptic": 120.66271390629689, "Oxygen saturation decreased": 8.141983407272932, "Pallor": 3.765217042152922, "Peripheral coldness": 3.158261590466468, "Photophobia": 2.932579084265248, "Premature baby": 3.379669654386116, "Premature delivery": 5.436984145381256, "Respiratory distress": 3.415195640407385, "Tachycardia": 4.515724209915355, "Tachypnoea": 6.076616561141799, "Tremor": 3.2910444945395603, "Urticaria": 2.7750423608216988, "Vomiting": 2.100632462346716}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/64.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/64.json
index 0ef87707ebe..e734599443c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/64.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/64.json
@@ -1 +1 @@
-{"Balance disorder ": 40.79774938731653, "Blood calcium decreased ": 312.51976967612313, "Cognitive disorder ": 76.04273014064854, "Constipation ": 20.514520952899133, "Creatinine renal clearance decreased ": 394.00520379334097, "Depressed level of consciousness ": 53.033409088262985, "Fall ": 14.23524208288276, "Hypotension ": 12.83796113095845, "Mobility decreased ": 50.21150595409613, "Orthostatic hypotension ": 119.60831844115344, "Pain ": 4.720173517702025, "Sedation ": 133.3674006465891, "Sedation complication ": 426.37345282822974, "Toxicity to various agents ": 18.03602615306352}
\ No newline at end of file
+{"Ascites": 3.427845662302708, "Bedridden": 7.034340330039236, "Blood pressure abnormal": 5.730729404650674, "Brain natriuretic peptide increased": 25.95471323723197, "Cardiac arrest": 2.0899313990081123, "Cardiac disorder": 2.335791926300617, "Cardiac failure": 4.727844941590773, "Cardiac failure congestive": 3.314884161874975, "Catheter site discharge": 103.27590703428268, "Cellulitis": 8.144903209767634, "Crepitations": 76.48666038426065, "Device occlusion": 17.347753591515986, "Dizziness exertional": 209.7620579019165, "Dyspnoea": 2.703698892190502, "Dyspnoea exertional": 7.761725619343239, "Epistaxis": 3.0098741339023487, "Feeding disorder": 6.791424561786785, "Feeling abnormal": 2.373964673760112, "Fluid retention": 15.685837016848804, "Flushing": 6.205495925250792, "Gastroenteritis viral": 20.69488058713773, "Haemoptysis": 3.306428790812638, "Hospitalisation": 2.973524653144432, "Hypervolaemia": 17.603873303054794, "Hypoacusis": 2.7914124321681166, "Hypotension": 2.117189430207232, "Hypoxia": 3.4917185393993955, "Ill-defined disorder": 3.788780259867505, "Illness": 2.336109502701676, "Infective exacerbation of chronic obstructive airways disease": 479.62612411042807, "Iron deficiency anaemia": 16.056181177196063, "Memory impairment": 2.550416963317032, "Nasal congestion": 8.602002550380435, "Oedema": 4.846218519886903, "Oedema peripheral": 5.576019965689068, "Oxygen saturation decreased": 3.533309226435505, "Pain in jaw": 20.35193601894708, "Pericardial effusion": 4.064654600447698, "Peripheral swelling": 2.21963515297341, "Premature delivery": 6.1744054254780325, "Productive cough": 10.476618575923926, "Pulmonary arterial hypertension": 31.80249356509378, "Pulmonary hypertension": 23.393007946377143, "Pulmonary oedema": 2.965118152980926, "Right ventricular failure": 55.299270670161874, "Skin discolouration": 2.4693956830556747, "Transfusion": 10.481514586680497, "Unevaluable event": 7.399869150646448, "Vascular device infection": 34.23346945907328, "Vitamin D decreased": 24.229767969928343, "Weight decreased": 2.920628145350486, "Weight increased": 3.97229738675915, "Wheezing": 2.1236771801334777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/640.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/640.json
index 7b7c9d8817e..f35ea4b42bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/640.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/640.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 8.319614759999924, "Acute kidney injury ": 4.064708399032767, "Acute myocardial infarction ": 3.221901239672089, "Acute pulmonary oedema ": 18.695398726695792, "Acute respiratory distress syndrome ": 8.637716010481396, "Acute respiratory failure ": 3.782422941823484, "Anaemia ": 2.7110627871705035, "Angina pectoris ": 2.0262142518999027, "Atrial fibrillation ": 4.909313221028522, "Atypical haemolytic uraemic syndrome ": 172.1886774658512, "Blood creatinine increased ": 2.000381789456292, "Blood pressure abnormal ": 2.6691477146763685, "Brain natriuretic peptide increased ": 23.84739247449997, "Cardiac disorder ": 4.42402150238164, "Cardiac dysfunction ": 17.464612573566626, "Cardiac failure ": 28.885854139518468, "Cardiac failure acute ": 30.085286773686374, "Cardiac failure chronic ": 8.164183437982837, "Cardiac failure congestive ": 6.127066970679661, "Cardiomyopathy ": 7.437395059637401, "Cardiotoxicity ": 39.31032247622005, "Cardiovascular disorder ": 2.125939971835359, "Cytomegalovirus infection ": 2.827877298428241, "Cytopenia ": 14.919717924560818, "Deep vein thrombosis ": 2.505526223715434, "Diastolic dysfunction ": 16.898640232751088, "Disease progression ": 3.762459405313519, "Ejection fraction decreased ": 16.78775303233424, "Electrocardiogram QT prolonged ": 2.5183917968040723, "Extravasation ": 23.3146038766316, "Febrile neutropenia ": 4.2226366309294905, "Haemolysis ": 6.098184267762944, "Haemolytic anaemia ": 9.987702033127498, "Haemolytic uraemic syndrome ": 31.87407445538449, "Hepatotoxicity ": 3.050491475426421, "Hypercalcaemia ": 4.883966232416806, "Hypertension ": 4.5968470327037, "Hypertensive crisis ": 7.544241445533405, "Hypervolaemia ": 5.086940471619675, "Infection ": 3.6894298200637, "Infusion site erythema ": 21.52517691668857, "Infusion site extravasation ": 133.22205638618416, "Infusion site pain ": 35.94145743829901, "Interstitial lung disease ": 2.255682987423362, "Left ventricular dysfunction ": 6.130115922622025, "Lymphocyte count decreased ": 4.577901740844326, "Microangiopathic haemolytic anaemia ": 70.73904893702823, "Myelosuppression ": 3.31188692151381, "Myocardial infarction ": 2.52365714068476, "Myocardial ischaemia ": 4.063369566035392, "Neuropathy peripheral ": 5.85183137619829, "Neutropenia ": 3.80222886730716, "Neutrophil count decreased ": 6.307002339479891, "Off label use ": 2.3235294685698795, "Pancytopenia ": 4.412198175842415, "Pericardial effusion ": 2.608800387345995, "Plasma cell myeloma ": 62.7449831745164, "Plasma cell myeloma recurrent ": 81.70648494324013, "Plasmacytoma ": 100.71757198604698, "Platelet count decreased ": 7.793683052878061, "Pleural effusion ": 2.3427551917676555, "Pneumonia ": 5.159392132966562, "Pneumonitis ": 4.666072869667799, "Posterior reversible encephalopathy syndrome ": 13.729202611871049, "Pulmonary arterial hypertension ": 8.058510628485982, "Pulmonary congestion ": 4.6360577124864655, "Pulmonary hypertension ": 26.788262446063747, "Pulmonary oedema ": 7.658450059119675, "Renal disorder ": 3.0720149174555167, "Renal failure ": 2.8325731897393047, "Renal impairment ": 4.343590076557106, "Respiratory tract infection ": 6.063136943316445, "Sepsis ": 4.617934973253056, "Septic shock ": 4.046336850114739, "Sudden death ": 2.90004545709605, "Therapy non-responder ": 2.2703102378504654, "Therapy partial responder ": 14.653631436557214, "Thrombocytopenia ": 7.325139805720767, "Thrombotic microangiopathy ": 98.46651724580556, "Thrombotic thrombocytopenic purpura ": 29.521433685834456, "Tumour lysis syndrome ": 72.67557157412313, "Unevaluable event ": 2.8518232924438056, "Upper respiratory tract infection ": 2.0821663667857635, "White blood cell count decreased ": 2.320966858333112}
\ No newline at end of file
+{"Alanine aminotransferase increased": 8.697353359952956, "Alopecia": 3.0801741479401343, "Anaemia": 2.0365977363857657, "Aphthous ulcer": 2.5346160377874063, "Aspartate aminotransferase increased": 9.53093687269678, "Autoimmune hepatitis": 4.662140448474119, "Blood alkaline phosphatase increased": 3.525878313786228, "Blood bilirubin increased": 5.722674809795118, "Blood creatinine increased": 2.1884418505127563, "Blood test abnormal": 3.143046533979188, "Bone pain": 2.0384641392787737, "Breast cancer": 12.82799912393435, "Breast cancer metastatic": 49.261672259770044, "Breast cancer recurrent": 21.115083688579197, "Breast mass": 5.230897797688006, "Carbohydrate antigen 15-3 increased": 43.474940418134246, "Carcinoembryonic antigen increased": 16.59629328567184, "Cell death": 11.223199500063604, "Decreased immune responsiveness": 22.14361000558108, "Disease progression": 3.0846933067524125, "Dry skin": 6.189108316200277, "Eating disorder": 2.374733127119992, "Electrocardiogram QT prolonged": 34.01419135788273, "Gamma-glutamyltransferase increased": 4.02842079859986, "Gastritis": 2.2851938233121345, "Glomerular filtration rate decreased": 2.372394845257269, "Granulocytopenia": 3.3637159545179687, "Haematocrit decreased": 5.334721197358444, "Haematotoxicity": 9.52389482859843, "Haemoglobin decreased": 2.735794503153165, "Hepatic cytolysis": 8.661838990026082, "Hepatic enzyme increased": 5.272050677932922, "Hepatic lesion": 8.380137348698895, "Hepatitis": 3.111126885078716, "Hepatitis acute": 3.785607562912243, "Hepatocellular injury": 3.398997123160076, "Hepatotoxicity": 31.71551463656383, "Hormone receptor positive HER2 negative breast cancer": 127.9005657796427, "Hypertransaminasaemia": 18.154727766307488, "Hypocalcaemia": 2.4715232658730213, "Immunodeficiency": 2.7072478251412746, "Jaundice": 2.493529651810884, "Laboratory test abnormal": 3.828933922779064, "Lacrimation increased": 4.072918278244662, "Leukopenia": 10.859375473052944, "Liver function test abnormal": 4.145631872372797, "Liver function test increased": 15.37090083488622, "Lymphocyte count decreased": 4.53511348170126, "Madarosis": 18.426697040160583, "Malignant neoplasm progression": 11.123173098770913, "Metastases to bone": 37.6961749525868, "Metastases to central nervous system": 6.32742206755942, "Metastases to liver": 15.010978097019722, "Metastases to lung": 16.481581218461102, "Metastases to lymph nodes": 10.127196207173396, "Metastases to spine": 35.82018120446954, "Metastasis": 26.336611257910043, "Mucosal inflammation": 2.0309088798652577, "Neoplasm": 4.562013437372067, "Neutropenia": 31.283010525680705, "Neutrophil count abnormal": 14.151957148948668, "Neutrophil count decreased": 6.248092525057419, "Pancytopenia": 2.684617507136792, "Pigmentation disorder": 5.251146733616541, "Pleural effusion": 3.042569644012836, "Pneumonitis": 10.406482214027596, "Pulmonary mass": 2.3870699690185435, "Red blood cell count decreased": 2.487172250706836, "Second primary malignancy": 4.840285452898643, "Skin exfoliation": 3.8624027475706058, "Skin reaction": 2.3447665588577515, "Skin toxicity": 7.598996909707168, "Spinal pain": 3.1869202919652992, "Therapy partial responder": 7.451667199649868, "Thrombocytopenia": 2.142022275980411, "Transaminases increased": 10.337128397716883, "Tumour marker increased": 25.20782291049756, "Vitiligo": 35.761569876368, "White blood cell count decreased": 5.314712591094712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/641.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/641.json
index 6ac1ede8fd8..497de5d60b6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/641.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/641.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.1361917251404274, "Accidental death ": 29.165359052692548, "Acidosis ": 3.792393558189127, "Acidosis hyperchloraemic ": 86.28816720019404, "Acute hepatic failure ": 4.500674491304552, "Aggression ": 5.456948478188613, "Agitation ": 2.73725489154508, "Anticonvulsant drug level above therapeutic ": 59.6952048166675, "Anticonvulsant drug level below therapeutic ": 29.92555352076628, "Anticonvulsant drug level increased ": 20.78181766814305, "Apathy ": 2.3270785485008907, "Aphasia ": 2.749392822087687, "Ataxia ": 8.123048307583291, "Atrioventricular block ": 5.693912997976467, "Atrioventricular block complete ": 12.777282161773538, "Atrioventricular block first degree ": 10.593833958024645, "Atrioventricular block second degree ": 16.249035453385087, "Aura ": 14.354161164108277, "Balance disorder ": 2.273378271303595, "Behaviour disorder ": 8.239082236076753, "Blood chloride increased ": 59.27522587770058, "Blood pH decreased ": 52.59603691086101, "Bradycardia ": 2.6396312013192538, "Cardiac arrest ": 2.941854227651338, "Cardio-respiratory arrest ": 3.013959851288462, "Cardiotoxicity ": 16.55230723782678, "Coarctation of the aorta ": 26.323474854741374, "Cognitive disorder ": 6.854390077970682, "Condition aggravated ": 3.0838644583301016, "Delusion ": 2.9395603900521805, "Depressed mood ": 2.986347093768269, "Dermatitis allergic ": 3.1859877651811277, "Developmental delay ": 4.735219401114477, "Diplopia ": 13.4681378783447, "Disease recurrence ": 4.323052699964014, "Drug effective for unapproved indication ": 9.19346987839598, "Drug ineffective ": 8.52711286977518, "Drug ineffective for unapproved indication ": 12.78595529019636, "Drug interaction ": 4.197265335711255, "Drug level decreased ": 8.494667313459026, "Drug reaction with eosinophilia and systemic symptoms ": 2.915482333301618, "Drug resistance ": 23.80958056751449, "Drug withdrawal convulsions ": 17.106628121265516, "Dysarthria ": 2.302824382642821, "Dyskinesia ": 2.1052859502188457, "Electrocardiogram QRS complex prolonged ": 20.45671238813517, "Encephalitis ": 2.815508154519119, "Encephalopathy ": 5.041979811322614, "Epilepsia partialis continua ": 198.26593683567603, "Epilepsy ": 17.709001398372894, "Exposure during pregnancy ": 3.5938983485307743, "Eye movement disorder ": 4.374897332151165, "Focal dyscognitive seizures ": 107.43070588901185, "Foetal exposure during pregnancy ": 3.9444909902749337, "Generalised tonic-clonic seizure ": 19.27628586420693, "Hyperbilirubinaemia ": 2.737058832351046, "Hypokalaemia ": 2.6388937202681504, "Hypoventilation ": 6.940039891958013, "Ileus ": 2.825157680906482, "Incorrect route of product administration ": 3.531745660410877, "Intensive care unit acquired weakness ": 117.70002922557444, "Intentional self-injury ": 2.473835428227112, "Irritability ": 2.7945336759756816, "Ischaemia ": 6.019949753652213, "Low birth weight baby ": 4.229220586169486, "Macroglossia ": 51.73103555922069, "Magnetic resonance imaging head abnormal ": 26.60207033401084, "Malnutrition ": 4.413136517393929, "Maternal exposure before pregnancy ": 8.317683615015683, "Maternal exposure during pregnancy ": 5.589082799254214, "Medication error ": 4.813553254079814, "Mental status changes ": 2.0492778987998506, "Metabolic acidosis ": 3.252722006761424, "Multiple organ dysfunction syndrome ": 2.147959179417983, "Multiple-drug resistance ": 290.1051023038506, "Muscle twitching ": 2.033885156191307, "Myoclonic epilepsy ": 35.509268693550474, "Myoclonus ": 6.623771508870318, "Neonatal seizure ": 96.87803389142852, "Neurotoxicity ": 14.167596075578876, "No adverse event ": 2.171717353624054, "Nodal rhythm ": 16.04346081937672, "Nystagmus ": 16.354456111143946, "Off label use ": 4.658081383789972, "Overdose ": 2.695134369652358, "Parkinsonism ": 2.7560485677460216, "Partial seizures ": 94.6800849143202, "Partial seizures with secondary generalisation ": 70.69648296726015, "Petit mal epilepsy ": 23.317908781810512, "Pneumonia aspiration ": 4.601091124815817, "Premature baby ": 3.538757496942015, "Premature delivery ": 10.297646952277118, "Product substitution issue ": 4.598251383730196, "Product use in unapproved indication ": 2.0259839391451173, "Product use issue ": 2.8886168233752945, "Psychotic disorder ": 3.3460934829432505, "Respiratory acidosis ": 7.003539522978501, "Respiratory rate increased ": 6.409744742454692, "Schizophrenia ": 3.3964395526113127, "Sedation ": 5.622788111011199, "Seizure ": 19.554717323718425, "Seizure cluster ": 71.11065700603598, "Sinus bradycardia ": 4.872571057607204, "Sinus tachycardia ": 3.424921018239825, "Skin warm ": 4.352616815764342, "Somnolence ": 2.954087173204213, "Staring ": 9.848477393531736, "Status epilepticus ": 122.35488654171624, "Stevens-Johnson syndrome ": 3.641457700222728, "Stupor ": 4.743530213663774, "Sudden unexplained death in epilepsy ": 60.46357006754184, "Therapeutic product effect incomplete ": 6.7957209408945, "Therapeutic response decreased ": 4.123239760761429, "Therapy non-responder ": 3.9451058821642935, "Tonic convulsion ": 27.920142904707436, "Toxic epidermal necrolysis ": 3.7998664101949, "Toxicity to various agents ": 3.667838127629629, "Treatment failure ": 7.615125630124234, "Treatment noncompliance ": 3.1059086895020696, "Unmasking of previously unidentified disease ": 91.91817135707836, "Unresponsive to stimuli ": 2.656981468627845, "Ventricular tachycardia ": 4.637612025704618, "White matter lesion ": 91.1754273084334, "Wrong patient received product ": 17.463635005115616}
\ No newline at end of file
+{"Adrenal insufficiency": 8.495009555188792, "Blood bilirubin increased": 3.808926616883882, "Blood creatinine increased": 2.252735372748044, "Cholelithiasis": 7.463124612674903, "Drug reaction with eosinophilia and systemic symptoms": 4.262973902770463, "Eosinophilia": 5.088487823700116, "Exposure during pregnancy": 6.178409151584386, "Faecaloma": 34.57568742409237, "Foetal exposure during pregnancy": 4.451475981750538, "Foetal growth restriction": 30.626395538135064, "Gamma-glutamyltransferase increased": 4.525833059178416, "Gastrointestinal disorder": 2.96236124395344, "Hepatic cytolysis": 11.390235639115737, "Hepatitis": 4.221094782526648, "Hyperbilirubinaemia": 18.051900573636303, "Jaundice": 6.632792584050142, "Live birth": 28.074936511916107, "Myocardial infarction": 3.8757845799855386, "Nephrolithiasis": 13.420026685681588, "Osteoarthritis": 4.465408946100279, "Osteoporosis": 2.5657577985167404, "Pancreatitis acute": 3.981455186552933, "Rash maculo-papular": 2.5458236966590846, "Renal colic": 40.01624325571736, "Sleep disorder": 2.7056596780610738, "Toxic epidermal necrolysis": 7.03745897433159, "Transaminases increased": 8.521036456661781, "Tubulointerstitial nephritis": 13.321725348363682}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/642.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/642.json
index fb10af4c377..2c2b6965faf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/642.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/642.json
@@ -1 +1 @@
-{"Cough ": 5.139991357606849, "Deafness ": 48.54162470990339, "Dysphonia ": 19.474822639182825, "Dyspnoea ": 2.058255230976417, "Haemoptysis ": 29.319983795503493, "Hospitalisation ": 13.920478688864495, "Infective pulmonary exacerbation of cystic fibrosis ": 159.55301259006828, "Off label use ": 5.56102101753493, "Pneumonia ": 4.2233570874079405, "Product dose omission issue ": 8.72727438088926}
\ No newline at end of file
+{"Anti factor VIII antibody positive": 3799.027533412679, "Anti factor VIII antibody test": 4233.530740644854, "Drug specific antibody": 316.4478466455078, "Factor VIII inhibition": 2221.579916647552, "Haemarthrosis": 316.6545819566622, "Haemorrhage": 41.95756806455338, "Inhibiting antibodies": 5583.317080444805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/643.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/643.json
index c6c0a1a6891..ea2294314bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/643.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/643.json
@@ -1 +1 @@
-{"Abortion induced ": 7.052488303638123, "Abortion spontaneous ": 2.324682801906542, "Acidosis ": 4.607419543616195, "Acquired gene mutation ": 33.238896139176376, "Acute hepatic failure ": 11.273679665831851, "Acute respiratory failure ": 3.186311737475385, "Alanine aminotransferase increased ": 2.064056259812392, "Anaemia ": 2.307640542166929, "Anion gap increased ": 32.785953755349425, "Aphthous ulcer ": 3.518316360843172, "Ascites ": 3.254510077463169, "Atrioventricular block complete ": 4.485437309553661, "Blood HIV RNA increased ": 44.768193447434825, "Blood alkaline phosphatase increased ": 2.0771486282320777, "Blood bilirubin increased ": 2.4118946503528287, "Blood lactic acid increased ": 18.976647894607986, "Blood triglycerides increased ": 2.870412780134394, "Bronchial hyperreactivity ": 32.69532221930547, "CD4 lymphocytes decreased ": 43.354955896552994, "CD4 lymphocytes increased ": 261.3801588479279, "CSF HIV escape syndrome ": 130.4136955617939, "Cachexia ": 7.106099736861508, "Cardiac murmur ": 5.138688176925462, "Cardiomyopathy ": 3.812885749307082, "Central nervous system lesion ": 9.040011859027077, "Cervical dysplasia ": 17.016252262998087, "Clavicle fracture ": 12.020634184707609, "Coagulopathy ": 2.989894582463382, "Conjunctivitis ": 2.0377013114823663, "Cryptococcosis ": 67.57234709249312, "Cytomegalovirus infection ": 4.344323192341329, "Dermatitis exfoliative ": 8.587223678650858, "Developmental delay ": 10.001351611838178, "Dilated cardiomyopathy ": 9.535679925356042, "Disseminated intravascular coagulation ": 2.933873924414, "Disseminated tuberculosis ": 22.91546804222777, "Drug resistance ": 10.233656324555149, "Drug-induced liver injury ": 2.6132957782497845, "Encephalitis ": 3.4205823407608933, "Encephalopathy ": 2.128890292933612, "Exposure during pregnancy ": 3.5717122455914927, "Failure to thrive ": 11.808773758426742, "Foetal death ": 4.398106692919867, "Foetal exposure during pregnancy ": 9.90235945375504, "Gamma-glutamyltransferase increased ": 2.071123211880536, "Granuloma ": 10.70561463647167, "HIV infection ": 84.26817768120603, "HIV-associated neurocognitive disorder ": 120.47572943055047, "Hepatic cirrhosis ": 2.423112709854484, "Hepatic encephalopathy ": 11.26171137728526, "Hepatic failure ": 8.14290679146103, "Hepatic function abnormal ": 2.688355880050378, "Hepatic steatosis ": 4.955490336452736, "Hepatitis ": 3.5392965537070853, "Hepatitis B ": 23.88655440692921, "Hepatitis B reactivation ": 30.03203632840066, "Hepatomegaly ": 24.622710880008647, "Hepatosplenomegaly ": 35.059602296950295, "Hepatotoxicity ": 7.983379440648861, "Hyperbilirubinaemia ": 3.627244885292161, "Hypercholesterolaemia ": 10.348829177875848, "Hyperlactacidaemia ": 26.679554344313985, "Hypertriglyceridaemia ": 16.378838925631023, "Hypoalbuminaemia ": 11.400843057685156, "Immune reconstitution inflammatory syndrome ": 240.4610028291607, "Injection site ulcer ": 37.96669611181628, "Intracranial pressure increased ": 8.50540643702899, "Jaundice ": 7.19710398418993, "Joint dislocation ": 7.401791026363712, "Kaposi's sarcoma ": 22.47138384422397, "Lactic acidosis ": 11.65414318888806, "Leprosy ": 201.357822559237, "Lipoatrophy ": 43.77061911694503, "Lipodystrophy acquired ": 23.014576515920773, "Live birth ": 6.563415513755155, "Liver function test abnormal ": 3.989939901651817, "Liver injury ": 5.951574222691468, "Low birth weight baby ": 6.447978394621438, "Low set ears ": 70.34112268644077, "Lung infiltration ": 6.108716639535079, "Lymphadenitis ": 23.85832530233409, "Macrocytosis ": 30.990901072345288, "Maternal exposure during pregnancy ": 2.054066480569113, "Meningitis cryptococcal ": 108.48959861935464, "Metabolic acidosis ": 5.42732983525791, "Mitochondrial toxicity ": 45.18824138855129, "Molluscum contagiosum ": 209.13265569696145, "Mouth ulceration ": 2.092034122131244, "Multiple-drug resistance ": 6.862826082977011, "Muscle spasticity ": 4.27607627736016, "Mycobacterial infection ": 38.404652003389984, "Mycobacterium avium complex infection ": 19.15581025306196, "Nephropathy toxic ": 4.099949308267737, "Nephrotic syndrome ": 5.450446214539015, "Neuropathy peripheral ": 4.929103031158866, "Nodular regenerative hyperplasia ": 98.9965773969692, "Oedema ": 2.3110925618244105, "Oral candidiasis ": 2.0457059839534777, "Pallor ": 2.7113708571224624, "Pancreatitis ": 2.1340268536953126, "Pancytopenia ": 2.6711823353871, "Papule ": 4.64319458223776, "Pathogen resistance ": 26.15368890218628, "Peripheral ischaemia ": 9.199746292940432, "Pneumocystis jirovecii pneumonia ": 4.145989802783515, "Polyneuropathy ": 2.8258993565133608, "Portal hypertension ": 19.0316419296194, "Pregnancy ": 8.208890626529648, "Premature baby ": 5.498225871974321, "Premature delivery ": 3.7358090888459534, "Progressive multifocal leukoencephalopathy ": 14.334710120202152, "Proteinuria ": 4.448180624175497, "Pulmonary tuberculosis ": 11.216014152130064, "Rash maculo-papular ": 2.3873286857142832, "Respiratory distress ": 2.346521605900777, "Skin lesion ": 9.466962784844132, "Skin mass ": 6.266463227898819, "Skin ulcer ": 2.3569622858840864, "Small for dates baby ": 14.663332322560398, "Splenomegaly ": 7.7809052219685775, "Stevens-Johnson syndrome ": 6.610783681243444, "Stillbirth ": 19.76986616190751, "Tachypnoea ": 3.907032519026677, "Thrombotic microangiopathy ": 4.217252247993341, "Toxic epidermal necrolysis ": 5.688526498137124, "Treatment failure ": 6.494508487398591, "Treatment noncompliance ": 4.319787513504023, "Trisomy 21 ": 52.8840389702044, "Tuberculoid leprosy ": 495.5222310372432, "Tuberculosis ": 18.855335508012224, "Viral load increased ": 8.295727128053338, "Viral mutation identified ": 118.0984434626281, "Virologic failure ": 70.34159354173681, "Visual acuity reduced ": 2.25264336248127}
\ No newline at end of file
+{"Blister": 74.64098888771214, "Genital erosion": 10901.437672281838, "Mucosal erosion": 3914.518092932005, "Rash": 10.87810226041852, "Stevens-Johnson syndrome": 241.22462686802143, "Toxic epidermal necrolysis": 240.08497729088683}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/644.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/644.json
index 656498151f0..31ca4df5e83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/644.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/644.json
@@ -1 +1 @@
-{"Abdominal hernia ": 2.355554112374048, "Abdominal infection ": 2.8007261832566064, "Abdominal operation ": 4.285708092401096, "Accident ": 2.685401816807518, "Accidental overdose ": 2.804114591425124, "Adverse reaction ": 5.15604615970874, "Age-related macular degeneration ": 3.054851123700373, "Amputation ": 9.558251057920785, "Amyloidosis ": 4.119105636990184, "Angiopathy ": 3.0127469238575046, "Angioplasty ": 3.13454567254831, "Ankle fracture ": 3.0201547846403467, "Anti-insulin antibody increased ": 11.4827297063163, "Anti-insulin antibody positive ": 35.35467224977318, "Aortic valve replacement ": 3.091085838662212, "Application site haemorrhage ": 2.942740076789228, "Arterial occlusive disease ": 3.070562735956315, "Back disorder ": 5.180304724963078, "Bedridden ": 2.98109301987898, "Blindness ": 9.949022010269813, "Blindness unilateral ": 9.289603944321792, "Blood glucose abnormal ": 21.267595568300774, "Blood glucose decreased ": 32.53224215992403, "Blood glucose fluctuation ": 33.10225696034378, "Blood glucose increased ": 26.23893052299988, "Blood insulin increased ": 5.649699182692904, "Blood ketone body ": 15.973630925859489, "Blood ketone body increased ": 5.025602694154197, "Blood potassium abnormal ": 2.0420735759786908, "Brain neoplasm ": 2.466813891399945, "Brain neoplasm malignant ": 2.474876572236433, "Cardiac disorder ": 4.062059302160344, "Cardiac failure congestive ": 2.4310257887861546, "Cardiac operation ": 13.57608205122151, "Cardiac pacemaker insertion ": 4.2814370869064735, "Carotid artery occlusion ": 2.081038859188506, "Carpal tunnel decompression ": 7.631887366467426, "Carpal tunnel syndrome ": 2.30440753332616, "Cartilage injury ": 3.403557763170366, "Cataract ": 17.612958042832147, "Cataract operation ": 29.513441420001868, "Catheter placement ": 2.0127790951034816, "Catheterisation cardiac ": 2.1533918040150595, "Cerebrovascular accident ": 5.316474719448628, "Cervical vertebral fracture ": 2.040806486824206, "Cold sweat ": 3.240300305767987, "Colon cancer ": 2.6898505623140774, "Colour blindness ": 2.510433966817682, "Concussion ": 3.592998592731743, "Corneal disorder ": 2.036670665358729, "Corneal transplant ": 10.779822262876351, "Coronary arterial stent insertion ": 2.897441379422162, "Coronary artery bypass ": 7.961946429772506, "Coronary artery occlusion ": 3.2478223314001315, "Corrective lens user ": 12.103450646998336, "Craniocerebral injury ": 2.578989249239867, "Cutaneous amyloidosis ": 43.80262519404179, "Dawn phenomenon ": 18.7737151219152, "Decubitus ulcer ": 2.2906985771402444, "Dementia ": 6.567545976733981, "Dementia Alzheimer's type ": 9.257957408696306, "Device breakage ": 8.740144279447813, "Device defective ": 9.42054227077613, "Device delivery system issue ": 7.268598659301825, "Device ineffective ": 4.120087918166374, "Device issue ": 22.43846052702027, "Device leakage ": 3.887095327567366, "Device malfunction ": 31.86453614509075, "Device mechanical issue ": 10.136790950380176, "Device operational issue ": 181.95344867559004, "Device use issue ": 10.727584409550742, "Diabetes mellitus inadequate control ": 34.88167805070266, "Diabetic coma ": 19.47879019768367, "Diabetic complication ": 15.237083892737688, "Diabetic eye disease ": 11.68373358423876, "Diabetic foot ": 14.29528794394822, "Diabetic foot infection ": 5.339476095327995, "Diabetic hyperglycaemic coma ": 38.245322027732605, "Diabetic ketoacidosis ": 7.140469382423087, "Diabetic ketosis ": 2.68361910625482, "Diabetic metabolic decompensation ": 14.86399800377885, "Diabetic nephropathy ": 8.231359648154577, "Diabetic neuropathy ": 12.52516731441894, "Diabetic retinal oedema ": 7.864417791616733, "Diabetic retinopathy ": 36.316652952061794, "Dialysis ": 9.391337975736286, "Diet noncompliance ": 18.552145469382896, "Disability ": 14.96175035963657, "Disease complication ": 3.3337199542159484, "Drug dose omission by device ": 3.3367689032953423, "Dysgraphia ": 2.4000154317689018, "Exercise lack of ": 9.15645998647078, "Expired device used ": 30.08451976321808, "Expired product administered ": 6.527091581590771, "Extra dose administered ": 3.702008819154552, "Extremity necrosis ": 2.7367277827813163, "Eye disorder ": 7.314288880185126, "Eye haemorrhage ": 8.69388154588961, "Eye infection ": 2.512431737706121, "Eye injury ": 2.0590117073730747, "Eye laser surgery ": 19.88466026274985, "Eye operation ": 18.48101624800588, "Fall ": 2.8465475844112254, "Fat tissue increased ": 4.102119489297582, "Feeling abnormal ": 2.016214862631184, "Femur fracture ": 2.0665955736795665, "Foetal chromosome abnormality ": 14.373825860095536, "Foetal exposure timing unspecified ": 11.488353533848493, "Food poisoning ": 2.3034974448165784, "Foot amputation ": 32.163226016377976, "Foot fracture ": 2.696563210055527, "Foot operation ": 8.162022156872656, "Foreign body ": 10.173637361600765, "Fractured coccyx ": 3.616584980095454, "Frustration tolerance decreased ": 2.05161792987045, "Gallbladder disorder ": 3.966837792041651, "Gallbladder operation ": 5.667574326000998, "Gangrene ": 5.498591432136584, "Gastrointestinal carcinoma ": 2.4089734502361937, "Glaucoma ": 7.999765461225416, "Glycosylated haemoglobin abnormal ": 19.278732903068644, "Glycosylated haemoglobin decreased ": 9.0988217705689, "Glycosylated haemoglobin increased ": 22.41465178153746, "Granuloma annulare ": 3.1316632171121155, "Haemodialysis ": 2.729196550000333, "Heart transplant ": 5.983111762565416, "Heart valve replacement ": 8.501457862876975, "Hepatic neoplasm ": 4.419910209243774, "Hernia repair ": 4.789465869472366, "Hip fracture ": 2.5774553987268227, "Hip surgery ": 2.464907337760337, "Hospitalisation ": 6.643300619071954, "Hunger ": 7.104387778185728, "Hyperbilirubinaemia neonatal ": 5.983111762565416, "Hyperglycaemia ": 37.92088185974232, "Hyperglycaemic unconsciousness ": 33.81586402493104, "Hyperhidrosis ": 2.5936102028849457, "Hyperinsulinaemia ": 5.084539383752847, "Hyperinsulinaemic hypoglycaemia ": 35.51893406154218, "Hypoacusis ": 3.9067271038355855, "Hypoglycaemia ": 35.50558244318425, "Hypoglycaemia neonatal ": 10.928689300473009, "Hypoglycaemia unawareness ": 23.61696632267947, "Hypoglycaemic coma ": 32.332054419103045, "Hypoglycaemic encephalopathy ": 12.699629962793276, "Hypoglycaemic seizure ": 76.27238200974567, "Hypoglycaemic unconsciousness ": 70.97806406373125, "Impaired gastric emptying ": 2.2463411472728363, "Inappropriate schedule of product administration ": 4.0772653104309216, "Incoherent ": 3.982307829384337, "Incorrect dosage administered ": 2.18674080243988, "Incorrect dose administered ": 2.9443627198476, "Incorrect dose administered by device ": 15.015704812605469, "Infarction ": 4.6052191510502185, "Infected skin ulcer ": 3.272265569619563, "Injection site atrophy ": 7.505751393557008, "Injection site bruising ": 8.494217211338384, "Injection site discolouration ": 10.297137879674729, "Injection site extravasation ": 6.496400305891565, "Injection site haemorrhage ": 13.88436056819454, "Injection site infection ": 3.261148882479572, "Injection site injury ": 11.465726945683135, "Injection site irritation ": 2.877473754646858, "Injection site mass ": 4.138643944136933, "Injection site nodule ": 6.113263817932968, "Injection site scar ": 7.296481033139446, "Injection site ulcer ": 2.685024518371889, "Injury associated with device ": 11.233303795427672, "Insulin autoimmune syndrome ": 4.587491908736293, "Insulin resistance ": 7.143135981648835, "Intentional dose omission ": 3.724648034225882, "Intercepted medication error ": 8.892152665791771, "Intervertebral disc disorder ": 2.325655146174492, "Intervertebral disc protrusion ": 3.4612659910634456, "Jaundice neonatal ": 2.950098941339058, "Joint injury ": 2.403380703548882, "Ketoacidosis ": 9.20026625241413, "Ketonuria ": 7.680987524592225, "Ketosis ": 10.197001980418134, "Kidney infection ": 2.634550357109484, "Knee arthroplasty ": 3.192065933464588, "Knee operation ": 5.001206293947275, "Lack of injection site rotation ": 31.081846666495817, "Laryngeal cancer ": 3.93473872246961, "Laziness ": 8.266323136106058, "Leg amputation ": 25.484349441692498, "Leukaemia ": 2.1767884414228598, "Limb injury ": 3.802973060122879, "Limb operation ": 5.096640728170159, "Lipoatrophy ": 2.372196513705373, "Lipodystrophy acquired ": 6.803861244929651, "Lipohypertrophy ": 6.934632441827537, "Liver transplant ": 2.5500822025690746, "Localised infection ": 5.6097284855433935, "Loose tooth ": 2.297169921965453, "Loss of consciousness ": 2.91776864610035, "Lower limb fracture ": 3.170695482729567, "Macular degeneration ": 7.950099283915953, "Macular hole ": 2.001171565263475, "Macular oedema ": 2.0776330519322554, "Medication error ": 4.563657120977821, "Memory impairment ": 2.296339684344088, "Moaning ": 2.468814694805832, "Morning sickness ": 4.977455456457704, "Multimorbidity ": 4.357369219031158, "Multiple drug therapy ": 2.111162610249816, "Multiple use of single-use product ": 35.313953739851186, "Myocardial infarction ": 2.813974321390978, "Neck injury ": 2.133220001331121, "Neck surgery ": 6.545261318096628, "Needle issue ": 2.0471796439686023, "Neoplasm ": 2.5714638328467165, "Neoplasm malignant ": 3.128611695573933, "Nervousness ": 3.1893565617729305, "Neuropathic arthropathy ": 7.403955855428577, "Ocular vascular disorder ": 3.7212808106720168, "Oesophageal carcinoma recurrent ": 90.24235533198424, "Osteomyelitis ": 3.1301743731143272, "Pancreatectomy ": 4.743943228297531, "Pancreatic carcinoma ": 2.2067507224613934, "Pancreatic disorder ": 8.725620980853542, "Pancreatic failure ": 2.8195342904801777, "Pancreatic neoplasm ": 2.942740076789228, "Parkinson's disease ": 3.070154399833378, "Pituitary tumour ": 2.7059341991172, "Pollakiuria ": 2.0080214006230075, "Poor peripheral circulation ": 3.076559145535576, "Postoperative wound infection ": 2.0365822140546115, "Pre-eclampsia ": 2.118468687474817, "Product administration error ": 12.107783947080874, "Product complaint ": 15.815190102846028, "Product counterfeit ": 4.233259282086727, "Product dose omission issue ": 3.4634842425507824, "Product odour abnormal ": 3.2670598897362484, "Product prescribing issue ": 2.644677382771607, "Product quality issue ": 3.993240893555362, "Product storage error ": 32.01127937242492, "Product use issue ": 4.266443632576364, "Prostatic operation ": 6.062088515207667, "Rectal tenesmus ": 3.1312781005560457, "Renal disorder ": 5.358813356077079, "Renal mass ": 2.236645973930348, "Renal neoplasm ": 2.047031086281009, "Renal transplant ": 19.756837442483185, "Retinal detachment ": 6.718202425451579, "Retinal disorder ": 12.232723493107692, "Retinal haemorrhage ": 6.276948999911585, "Retinal injury ": 6.299003078128232, "Retinopathy ": 18.3638935691191, "Retinopathy proliferative ": 20.994863863076667, "Road traffic accident ": 4.270329993671052, "Rotator cuff repair ": 6.822033855851455, "Rotator cuff syndrome ": 2.372459925156543, "Sciatic nerve injury ": 4.982175767001625, "Shock hypoglycaemic ": 20.4753558819406, "Shoulder arthroplasty ": 2.6598471128970176, "Shoulder fracture ": 3.490140314836656, "Shoulder operation ": 4.958150420739237, "Silent myocardial infarction ": 6.3251579321365, "Skin ulcer ": 2.467221645283989, "Sluggishness ": 3.863098570380712, "Sopor ": 3.517566436496857, "Speech disorder ": 2.1145559751661924, "Spinal cord injury ": 2.1571694582739065, "Spinal disorder ": 3.4331766071536385, "Spinal operation ": 6.268458929239602, "Staphylococcal infection ": 2.2280380165844624, "Stent placement ": 4.091713715909145, "Surgery ": 4.072685878518728, "Suspected counterfeit product ": 2.553070957193883, "Suspected product quality issue ": 3.0273377899949354, "Therapeutic product ineffective ": 2.1525876210694275, "Thirst ": 2.5293677589527666, "Throat cancer ": 2.446919768280144, "Thyroid cancer ": 2.114894516299211, "Toe amputation ": 22.55648727604941, "Trigger finger ": 2.550620985438864, "Unevaluable event ": 5.222064746174999, "Upper limb fracture ": 3.18450455080312, "Urinary tract infection ": 2.062596537718892, "Urine ketone body present ": 7.59532391588997, "Vascular dementia ": 4.798684584508915, "Vascular graft ": 16.099129662206444, "Vascular occlusion ": 5.3724549000572965, "Venous occlusion ": 2.741200331716972, "Vision blurred ": 2.247417440345172, "Visual impairment ": 8.79495953480712, "Vitreous disorder ": 4.320915376117243, "Vitreous haemorrhage ": 11.539845453603514, "Walking aid user ": 7.077519893082665, "Weight increased ": 2.867050896740208, "Wheelchair user ": 12.950056083919891, "Wrist fracture ": 2.320505649155228, "Wrong device used ": 21.310252250294347, "Wrong product administered ": 7.689404909033826, "Wrong technique in device usage process ": 12.03079139240895, "Wrong technique in product usage process ": 3.0799391981728483}
\ No newline at end of file
+{"Anti factor VIII antibody positive": 1329.062886870339, "Contusion": 7.802982581547032, "Epistaxis": 5.478776902851115, "Fall": 3.630717269851124, "Haemarthrosis": 1441.2948583006842, "Haemorrhage": 103.14428869768828, "Joint injury": 67.81377526866912, "Joint swelling": 4.475144717503885, "Limb injury": 63.36811877106136, "Muscle haemorrhage": 231.06293822332853, "Peripheral swelling": 2.661680718730477, "Product dose omission issue": 2.3884121023472304, "Traumatic haemorrhage": 891.2060412906651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/645.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/645.json
index c86187d462f..75127f3e624 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/645.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/645.json
@@ -1 +1 @@
-{"Intraocular pressure increased ": 308.75645539874336}
\ No newline at end of file
+{"Abortion spontaneous": 19.63690358637492, "Aggression": 4.067437477392114, "Amino acid level increased": 2041.1466107797487, "Anaphylactic reaction": 4.330653653870778, "Anxiety": 2.212205437105592, "Depression": 4.440819536219736, "Exposure during pregnancy": 3.4241582567129507, "Gastrooesophageal reflux disease": 3.1855983746183605, "Maternal exposure during pregnancy": 14.039416233340251, "Premature baby": 8.506722303138876, "Seizure": 4.215050839042136, "Therapy non-responder": 8.787689447599705, "Throat tightness": 7.929692773991227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/646.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/646.json
index 577df95ef94..85d8f1ee727 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/646.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/646.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 7.180708771614565, "Abulia ": 14.08647118210864, "Activation syndrome ": 91.89019179892796, "Affective disorder ": 5.976906178180464, "Aggression ": 6.252346600649236, "Agitation ": 4.095702196641973, "Akathisia ": 50.277405798980354, "Anger ": 13.500701450748942, "Anxiety ": 3.307393947750888, "Apathy ": 4.918695597125134, "Autism spectrum disorder ": 4.740991880305043, "Aversion ": 58.86945696779946, "Bipolar I disorder ": 32.33995462696452, "Bipolar disorder ": 57.76609162170238, "Blepharospasm ": 3.237365173149017, "Blood prolactin increased ": 26.334610390357557, "Blood triglycerides increased ": 2.547497133082527, "Blunted affect ": 30.981787930057248, "Bradyphrenia ": 3.042817636044981, "Brain injury ": 3.477766499593059, "Bruxism ": 17.753558010888593, "Catatonia ": 13.731708102417722, "Cognitive disorder ": 2.251336355519759, "Cogwheel rigidity ": 19.781820449664394, "Completed suicide ": 3.998016621997286, "Crying ": 5.783397321441616, "Decreased activity ": 3.881731015195834, "Delusion ": 18.190018083578504, "Depressed mood ": 4.72369524387399, "Depression ": 5.1761089234389415, "Depressive symptom ": 8.108743596904244, "Diabetes mellitus ": 2.2540518432200427, "Drooling ": 10.254229855473769, "Drug effective for unapproved indication ": 9.497261143728627, "Drug ineffective for unapproved indication ": 5.112215333049673, "Dysarthria ": 2.317266486983779, "Dyskinesia ": 12.065524896485076, "Dysphemia ": 5.721153603028377, "Dystonia ": 43.07225106585189, "Emotional disorder ": 2.8932844919848923, "Emotional poverty ": 13.5690236058716, "Energy increased ": 13.99529255170698, "Erectile dysfunction ": 4.246022239549406, "Euphoric mood ": 4.098198385265858, "Extra dose administered ": 2.005714666111704, "Extrapyramidal disorder ": 16.212708043419088, "Eye movement disorder ": 2.780552109262024, "Fear ": 7.643842398239859, "Feeling abnormal ": 4.795505277579212, "Feeling jittery ": 4.893955864089135, "Feeling of despair ": 10.379118698451762, "Flat affect ": 17.755906768969258, "Frustration tolerance decreased ": 5.47558127092253, "Galactorrhoea ": 11.607195555130296, "Gastric bypass ": 30.53803614419454, "Gestational diabetes ": 5.311467690673049, "Hallucination ": 4.676230114320489, "Hallucination, auditory ": 30.601852506935607, "Hallucination, visual ": 3.087308699109023, "Head injury ": 2.049495255294012, "Homicidal ideation ": 14.177840724623346, "Hostility ": 10.946057070999917, "Hyperprolactinaemia ": 51.74356191240668, "Hypersomnia ": 2.4351623363602144, "Hyperventilation ": 3.0548652769830373, "Hypomania ": 8.795684790603806, "Impulsive behaviour ": 12.267298597575476, "Increased appetite ": 7.884965215555664, "Initial insomnia ": 2.301809176501264, "Insomnia ": 3.4342148837405047, "Intentional dose omission ": 4.296082312664163, "Intentional self-injury ": 8.39948755539375, "Irritability ": 3.546732087007208, "Logorrhoea ": 8.188355011155997, "Major depression ": 10.670326275528408, "Malabsorption ": 2.478510551521283, "Mania ": 36.81915325790826, "Mental disorder ": 6.165308565013028, "Mental impairment ": 5.767121979839229, "Metabolic surgery ": 20.2521963370098, "Middle insomnia ": 2.0868334972548768, "Mood altered ": 4.688870847023732, "Mood swings ": 6.207860266090219, "Muscle rigidity ": 6.943846111455374, "Musculoskeletal stiffness ": 2.049140616977808, "Near death experience ": 4.683636252556969, "Negative thoughts ": 12.210437613776168, "Nervousness ": 2.082205177468173, "Neuroleptic malignant syndrome ": 11.85959994627396, "Nightmare ": 2.063048762003044, "Obesity ": 4.261541041772467, "Obsessive thoughts ": 19.337806689170385, "Obsessive-compulsive disorder ": 4.327155416712492, "Oculogyric crisis ": 89.56453064257155, "Off label use ": 5.092843707370842, "Oromandibular dystonia ": 41.06326569656673, "Panic attack ": 6.119671745237946, "Panic reaction ": 3.1106919729643723, "Paranoia ": 13.471220864343618, "Parkinson's disease ": 3.670973563437508, "Parkinsonism ": 10.460422764586962, "Persecutory delusion ": 11.349998166176958, "Personality change ": 2.784330587886993, "Physical assault ": 13.267118074208542, "Physical deconditioning ": 3.953999088860821, "Pneumonia aspiration ": 2.0572458510186435, "Polydipsia ": 9.138487424797011, "Poor quality sleep ": 2.4843087966396897, "Post-traumatic stress disorder ": 15.111620668454814, "Pregnancy ": 11.366393886709735, "Prescribed overdose ": 4.176899015217927, "Prescribed underdose ": 26.845203589340443, "Product administered to patient of inappropriate age ": 5.531422011277158, "Product administration error ": 6.974510321680538, "Product dose omission issue ": 2.319771403414354, "Product use in unapproved indication ": 2.119225659326246, "Psychiatric decompensation ": 8.074227299509102, "Psychiatric symptom ": 15.73146219237784, "Psychomotor hyperactivity ": 5.52750750606705, "Psychotic disorder ": 10.779290717492495, "Psychotic symptom ": 37.1786391081467, "Restless legs syndrome ": 5.713083208448298, "Restlessness ": 8.107758523362023, "Road traffic accident ": 2.295264592706149, "Salivary hypersecretion ": 6.851420571599473, "Schizoaffective disorder ": 19.77172888196404, "Schizophrenia ": 37.88318525932536, "Screaming ": 6.0883371726773685, "Sedation ": 3.95296038508841, "Sedation complication ": 3.336596807987536, "Seizure ": 2.0623166900481475, "Self-destructive behaviour ": 15.265871679827743, "Self-injurious ideation ": 25.60733161160183, "Serotonin syndrome ": 2.6108654168673247, "Sleep apnoea syndrome ": 2.118349250164602, "Social avoidant behaviour ": 6.315277835281716, "Soliloquy ": 22.695998013031364, "Somnambulism ": 5.197930357832098, "Somnolence ": 2.1809391711168744, "Speech disorder ": 2.904407322262264, "Stress ": 2.730203913937683, "Suicidal behaviour ": 12.417734567667315, "Suicidal ideation ": 26.10870667323299, "Suicide attempt ": 6.126282653605212, "Swollen tongue ": 3.63075821030564, "Tachyphrenia ": 31.770158734798905, "Tardive dyskinesia ": 107.3720914635213, "Temperature intolerance ": 2.642258719239546, "Therapeutic response decreased ": 2.0228410513480406, "Therapeutic response unexpected ": 3.0705175838565784, "Therapy cessation ": 33.821684600323465, "Therapy interrupted ": 34.15821001601951, "Thinking abnormal ": 7.239894630544351, "Tic ": 6.425829670251649, "Tongue movement disturbance ": 25.67288451600384, "Torticollis ": 11.176071403279094, "Treatment noncompliance ": 3.0342293954792225, "Tremor ": 3.2009078344346245, "Trismus ": 10.586490390139504, "Underdose ": 3.113041601358661, "Urinary incontinence ": 2.102421555931233, "Urinary retention ": 3.586005534046205, "Violence-related symptom ": 10.704638481319, "Weight increased ": 6.031952881055004, "Withdrawal syndrome ": 3.3743231697275164, "Wrong technique in product usage process ": 4.8387584713696965}
\ No newline at end of file
+{"Activated partial thromboplastin time prolonged": 11.55304010966129, "Acute graft versus host disease in skin": 6.362211731247109, "Acute lymphocytic leukaemia": 90.54376377264838, "Acute lymphocytic leukaemia recurrent": 584.0499794171417, "Acute lymphocytic leukaemia refractory": 132.35339382448248, "Aphasia": 3.97509849087988, "Apraxia": 11.735727412449387, "Atelectasis": 4.00220821779747, "B precursor type acute leukaemia": 80.35453078541197, "B-cell aplasia": 3400.4029704541445, "B-cell type acute leukaemia": 203.59502564334872, "B-lymphocyte count abnormal": 1929.585872279043, "Bacteraemia": 4.141837613329832, "Blast cell count increased": 86.52630852031776, "Blood albumin decreased": 7.287499776215023, "Blood calcium decreased": 5.421222115419543, "Blood chloride increased": 10.89032492788458, "Blood fibrinogen decreased": 66.71422532841393, "Blood fibrinogen increased": 50.14012708155608, "Blood lactate dehydrogenase increased": 6.22835359434703, "Blood phosphorus decreased": 7.981567287742407, "Blood potassium decreased": 3.0609553439728923, "Blood pressure systolic decreased": 5.956464603966593, "Bone lesion": 14.103931280489345, "Bone marrow disorder": 11.097710664018605, "Bone marrow failure": 6.96689146524679, "Brain oedema": 3.950546775118291, "C-reactive protein decreased": 31.558231966858525, "C-reactive protein increased": 6.127000129911542, "Capillary leak syndrome": 25.71118295925762, "Carbon dioxide decreased": 21.223514497999616, "Central nervous system leukaemia": 89.18146417743372, "Central nervous system lymphoma": 26.42000969427001, "Clostridium difficile colitis": 5.132989245704502, "Coagulopathy": 18.811886412506823, "Congenital aplasia": 10.021218466821376, "Cytokine release syndrome": 586.2176351714313, "Cytokine storm": 35.87193091251117, "Cytomegalovirus infection": 3.52619971716912, "Cytopenia": 29.9609563353194, "Diffuse large B-cell lymphoma": 281.69919468589995, "Diffuse large B-cell lymphoma recurrent": 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"Hypoxia": 16.491645778492636, "Immune effector cell-associated neurotoxicity syndrome": 442.8114166519695, "Incontinence": 2.358406836584282, "Inflammatory marker increased": 7.161187893129215, "Interleukin level increased": 125.56499856297658, "Intracranial pressure increased": 3.5156190512935344, "Left ventricular dysfunction": 6.337394284218184, "Leukaemia recurrent": 10.81243580264405, "Localised oedema": 2.921036106234984, "Loss of CAR T-cell persistence": 1719.9631390808895, "Lymphocyte count decreased": 22.333219464869316, "Lymphoma": 7.175316025947196, "Lymphopenia": 2.6902697229658705, "Malignant neoplasm progression": 16.231291541400513, "Mean cell haemoglobin concentration increased": 63.47993213053206, "Mental status changes": 5.526766816122155, "Metastases to central nervous system": 2.8065009163255565, "Metastases to meninges": 17.4087257488375, "Minimal residual disease": 403.7936048847712, "Multiple organ dysfunction syndrome": 5.148071230720524, "Myelodysplastic syndrome": 5.44973197528824, "Nervous system disorder": 6.08858583728322, "Neurological decompensation": 19.10260970130401, "Neurotoxicity": 66.64143421379781, "Neutropenia": 2.9344232435118065, "Neutrophil count decreased": 4.987939989390185, "Non-Hodgkin's lymphoma": 8.82161451713208, "Oliguria": 4.218055009751324, "Optic neuritis": 2.4056935949643994, "Out of specification test results": 994.662270761931, "Oxygen saturation decreased": 3.050256533805608, "Pancytopenia": 6.835060632109216, "Platelet count decreased": 4.198761806161137, "Pleural effusion": 2.0654266895904483, "Pneumonia fungal": 7.032640355274652, "Post-depletion B-cell recovery": 14899.032451876572, "Protein total decreased": 9.225437549353147, "Prothrombin time prolonged": 7.042070123370153, "Pyrexia": 2.6153469476510223, "Red blood cell count decreased": 5.592592327324308, "Red cell distribution width increased": 9.114433446266275, "Remission not achieved": 95.7618000705373, "Respiratory rate increased": 3.822219750053017, "Second primary malignancy": 20.21401009052694, "Septic shock": 3.3417569749010974, "Serum ferritin increased": 65.39416401357049, "T-cell lymphoma": 33.08506731837743, "Tachycardia": 2.503839111525984, "Tachypnoea": 7.786120482614289, "Therapeutic product effect incomplete": 4.7445036753695, "Therapy non-responder": 5.525414209116877, "Therapy partial responder": 4.801821557044752, "Thrombocytopenia": 2.278906418477689, "Transformation to acute myeloid leukaemia": 77.33313869724412, "Tumour lysis syndrome": 10.239030383835916, "White blood cell count decreased": 2.96821724130266, "White blood cell count increased": 2.604793675326871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/647.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/647.json
index 267eb474496..14f447535a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/647.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/647.json
@@ -1 +1 @@
-{"Completed suicide ": 27.82921476166062, "Death ": 14.433444390086231}
\ No newline at end of file
+{"Acute coronary syndrome": 8.319614759999924, "Acute kidney injury": 4.064708399032767, "Acute myocardial infarction": 3.221901239672089, "Acute pulmonary oedema": 18.695398726695792, "Acute respiratory distress syndrome": 8.637716010481396, "Acute respiratory failure": 3.782422941823484, "Anaemia": 2.7110627871705035, "Angina pectoris": 2.0262142518999027, "Atrial fibrillation": 4.909179004961207, "Atypical haemolytic uraemic syndrome": 172.1886774658512, "Blood creatinine increased": 2.000381789456292, "Blood pressure abnormal": 2.6691477146763685, "Brain natriuretic peptide increased": 23.84739247449997, "Cardiac disorder": 4.42402150238164, "Cardiac dysfunction": 17.464612573566626, "Cardiac failure": 28.883190534800285, "Cardiac failure acute": 30.085286773686374, "Cardiac failure chronic": 8.164183437982837, "Cardiac failure congestive": 6.126602698390537, "Cardiomyopathy": 7.437395059637401, "Cardiotoxicity": 39.31032247622005, "Cardiovascular disorder": 2.125939971835359, "Cytomegalovirus infection": 2.827877298428241, "Cytopenia": 14.90779378283181, "Deep vein thrombosis": 2.505526223715434, "Diastolic dysfunction": 16.898640232751088, "Disease progression": 3.762459405313519, "Ejection fraction decreased": 16.78775303233424, "Electrocardiogram QT prolonged": 2.5183917968040723, "Extravasation": 23.3146038766316, "Febrile neutropenia": 4.2226366309294905, "Haemolysis": 6.098184267762944, "Haemolytic anaemia": 9.987702033127498, "Haemolytic uraemic syndrome": 31.87407445538449, "Hepatotoxicity": 3.050491475426421, "Hypercalcaemia": 4.883966232416806, "Hypertension": 4.596799504468892, "Hypertensive crisis": 7.544241445533405, "Hypervolaemia": 5.086940471619675, "Infection": 3.6894298200637, "Infusion site erythema": 21.52517691668857, "Infusion site extravasation": 133.22205638618416, "Infusion site pain": 35.94145743829901, "Interstitial lung disease": 2.255682987423362, "Left ventricular dysfunction": 6.130115922622025, "Lymphocyte count decreased": 4.577901740844326, "Microangiopathic haemolytic anaemia": 70.73904893702823, "Myelosuppression": 3.31188692151381, "Myocardial infarction": 2.52365714068476, "Myocardial ischaemia": 4.063369566035392, "Neuropathy peripheral": 5.85165338434345, "Neutropenia": 3.8020651648461614, "Neutrophil count decreased": 6.307002339479891, "Off label use": 2.323437884809477, "Pancytopenia": 4.412198175842415, "Pericardial effusion": 2.608800387345995, "Plasma cell myeloma": 62.7449831745164, "Plasma cell myeloma recurrent": 81.70648494324013, "Plasmacytoma": 100.71757198604698, "Platelet count decreased": 7.793683052878061, "Pleural effusion": 2.342539379053933, "Pneumonia": 5.159392132966562, "Pneumonitis": 4.666072869667799, "Posterior reversible encephalopathy syndrome": 13.729202611871049, "Pulmonary arterial hypertension": 8.058510628485982, "Pulmonary congestion": 4.6360577124864655, "Pulmonary hypertension": 26.788262446063747, "Pulmonary oedema": 7.657442046480595, "Renal disorder": 3.071561436671101, "Renal failure": 2.8325731897393047, "Renal impairment": 4.343590076557106, "Respiratory tract infection": 6.063136943316445, "Sepsis": 4.617934973253056, "Septic shock": 4.046336850114739, "Sudden death": 2.90004545709605, "Therapy non-responder": 2.27011183267614, "Therapy partial responder": 14.653631436557214, "Thrombocytopenia": 7.324449002106805, "Thrombotic microangiopathy": 98.46651724580556, "Thrombotic thrombocytopenic purpura": 29.521433685834456, "Tumour lysis syndrome": 72.67557157412313, "Unevaluable event": 2.8518232924438056, "Upper respiratory tract infection": 2.0821663667857635, "White blood cell count decreased": 2.320966858333112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/648.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/648.json
index 21883ec185e..ea0fa02e19a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/648.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/648.json
@@ -1 +1 @@
-{"Drug ineffective ": 2.871209371660338, "Drug interaction ": 19.470729618646136, "Hepatitis C ": 39.02832528485297, "Treatment failure ": 17.78295435024443}
\ No newline at end of file
+{"Abortion spontaneous": 2.1361917251404274, "Accidental death": 29.165359052692548, "Acidosis": 3.792393558189127, "Acidosis hyperchloraemic": 86.28816720019404, "Acute hepatic failure": 4.500674491304552, "Aggression": 5.456948478188613, "Agitation": 2.73725489154508, "Anticonvulsant drug level above therapeutic": 59.6952048166675, "Anticonvulsant drug level below therapeutic": 29.92555352076628, "Anticonvulsant drug level increased": 20.78181766814305, "Apathy": 2.3270785485008907, "Aphasia": 2.7489829877777985, "Ataxia": 8.123048307583291, "Atrioventricular block": 5.693912997976467, "Atrioventricular block complete": 12.777282161773538, "Atrioventricular block first degree": 10.593833958024645, "Atrioventricular block second degree": 16.249035453385087, "Aura": 14.354161164108277, "Balance disorder": 2.273378271303595, "Behaviour disorder": 8.239082236076753, "Blood chloride increased": 59.27522587770058, "Blood pH decreased": 52.59603691086101, "Bradycardia": 2.6395483822902133, "Cardiac arrest": 2.941854227651338, "Cardio-respiratory arrest": 3.013959851288462, "Cardiotoxicity": 16.55230723782678, "Coarctation of the aorta": 26.323474854741374, "Cognitive disorder": 6.854390077970682, "Condition aggravated": 3.0838644583301016, "Delusion": 2.9395603900521805, "Depressed mood": 2.986347093768269, "Dermatitis allergic": 3.1859877651811277, "Developmental delay": 4.733372050473918, "Diplopia": 13.4681378783447, "Disease recurrence": 4.323052699964014, "Drug effective for unapproved indication": 9.19346987839598, "Drug ineffective": 8.527049565503601, "Drug ineffective for unapproved indication": 12.78595529019636, "Drug interaction": 4.197265335711255, "Drug level decreased": 8.494667313459026, "Drug reaction with eosinophilia and systemic symptoms": 2.9152413046465577, "Drug resistance": 23.80958056751449, "Drug withdrawal convulsions": 17.106628121265516, "Dysarthria": 2.302824382642821, "Dyskinesia": 2.1052859502188457, "Electrocardiogram QRS complex prolonged": 20.45671238813517, "Encephalitis": 2.815508154519119, "Encephalopathy": 5.041979811322614, "Epilepsia partialis continua": 198.26593683567603, "Epilepsy": 17.709001398372894, "Exposure during pregnancy": 3.5938983485307743, "Eye movement disorder": 4.374897332151165, "Focal dyscognitive seizures": 107.43070588901185, "Foetal exposure during pregnancy": 3.9444909902749337, "Generalised tonic-clonic seizure": 19.27628586420693, "Hyperbilirubinaemia": 2.737058832351046, "Hypokalaemia": 2.6388937202681504, "Hypoventilation": 6.940039891958013, "Ileus": 2.825157680906482, "Incorrect route of product administration": 3.531745660410877, "Intensive care unit acquired weakness": 117.70002922557444, "Intentional self-injury": 2.473835428227112, "Irritability": 2.794400076202445, "Ischaemia": 6.019949753652213, "Low birth weight baby": 4.229220586169486, "Macroglossia": 51.73103555922069, "Magnetic resonance imaging head abnormal": 26.60207033401084, "Malnutrition": 4.413136517393929, "Maternal exposure before pregnancy": 8.317683615015683, "Maternal exposure during pregnancy": 5.589082799254214, "Medication error": 4.813207119092383, "Mental status changes": 2.0492778987998506, "Metabolic acidosis": 3.252722006761424, "Multiple organ dysfunction syndrome": 2.147959179417983, "Multiple-drug resistance": 290.1051023038506, "Muscle twitching": 2.033885156191307, "Myoclonic epilepsy": 35.509268693550474, "Myoclonus": 6.623771508870318, "Neonatal seizure": 96.87803389142852, "Neurotoxicity": 14.167596075578876, "No adverse event": 2.171717353624054, "Nodal rhythm": 16.04346081937672, "Nystagmus": 16.354456111143946, "Off label use": 4.657897493392906, "Overdose": 2.695134369652358, "Parkinsonism": 2.7560485677460216, "Partial seizures": 94.6800849143202, "Partial seizures with secondary generalisation": 70.69648296726015, "Petit mal epilepsy": 23.317908781810512, "Pneumonia aspiration": 4.601091124815817, "Premature baby": 3.538757496942015, "Premature delivery": 10.297646952277118, "Product substitution issue": 4.598251383730196, "Product use in unapproved indication": 2.025920702086735, "Product use issue": 2.8886168233752945, "Psychotic disorder": 3.3460934829432505, "Respiratory acidosis": 7.003539522978501, "Respiratory rate increased": 6.409744742454692, "Schizophrenia": 3.3964395526113127, "Sedation": 5.622788111011199, "Seizure": 19.55252810799171, "Seizure cluster": 71.11065700603598, "Sinus bradycardia": 4.872571057607204, "Sinus tachycardia": 3.424921018239825, "Skin warm": 4.352616815764342, "Somnolence": 2.9540545635511197, "Staring": 9.848477393531736, "Status epilepticus": 122.35488654171624, "Stevens-Johnson syndrome": 3.641457700222728, "Stupor": 4.743530213663774, "Sudden unexplained death in epilepsy": 60.46357006754184, "Therapeutic product effect incomplete": 6.7957209408945, "Therapeutic response decreased": 4.123239760761429, "Therapy non-responder": 3.944760654412697, "Tonic convulsion": 27.920142904707436, "Toxic epidermal necrolysis": 3.7998664101949, "Toxicity to various agents": 3.667838127629629, "Treatment failure": 7.615125630124234, "Treatment noncompliance": 3.1059086895020696, "Unmasking of previously unidentified disease": 91.91817135707836, "Unresponsive to stimuli": 2.656689051524855, "Ventricular tachycardia": 4.637612025704618, "White matter lesion": 91.1754273084334, "Wrong patient received product": 17.463635005115616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/649.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/649.json
index 1dcf0ff08d0..e058b3df497 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/649.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/649.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.440540793052435, "Acne ": 3.6720547016425527, "Acute lung injury ": 121.48399723409564, "Adverse drug reaction ": 2.203797540593831, "Ankle fracture ": 4.64320478763225, "Arthritis ": 5.498450337347067, "Arthropathy ": 2.899907381522649, "Blood cholesterol increased ": 2.1151043422958065, "Blood pressure abnormal ": 2.2599612764483537, "Blood pressure diastolic abnormal ": 22.28836922140312, "Blood pressure systolic increased ": 4.150563339078497, "Bone erosion ": 10.50742902563494, "C-reactive protein increased ": 7.850170346210012, "Cellulitis ": 2.681727716739034, "Clostridium difficile infection ": 5.549922001958949, "Condition aggravated ": 2.159577601642348, "Crepitations ": 17.464828796730547, "Cytopenia ": 4.381435759784064, "Deformity ": 9.379888225363912, "Device fastener issue ": 1472.9822109090417, "Diverticulitis ": 14.45426103677082, "Drug hypersensitivity ": 3.047417980423731, "Drug ineffective ": 4.235597930815383, "Drug intolerance ": 15.055739002464843, "Drug-induced liver injury ": 5.118796236421479, "Dry eye ": 4.9452024721361205, "Dyspepsia ": 4.0609809584913, "Dysstasia ": 2.7147257995655925, "Exostosis ": 31.059253648534103, "Fibromyalgia ": 2.7841927450300004, "Foot deformity ": 13.97841201200264, "Foot fracture ": 2.918000043729168, "Frustration tolerance decreased ": 16.532099030372613, "Gastrointestinal disorder ": 5.070102868504719, "General physical health deterioration ": 2.8663575442288405, "General symptom ": 35.48625296959275, "Gingival abscess ": 172.28820687917533, "Gingival disorder ": 31.410858184114343, "Grip strength decreased ": 8.337991583931341, "Hand deformity ": 6.888812585821236, "Heart rate decreased ": 2.087218048957104, "Hepatic enzyme increased ": 4.739553704481245, "Hepatitis ": 3.167326315168878, "Ill-defined disorder ": 2.501292671760513, "Immunodeficiency ": 9.104319473849802, "Impaired healing ": 2.775554771305538, "Inflammation ": 3.305211469604857, "Joint dislocation ": 9.49179086184493, "Joint effusion ": 11.517791896533558, "Joint range of motion decreased ": 4.962151690682721, "Joint space narrowing ": 153.82420829794847, "Joint stiffness ": 2.841665804021809, "Joint swelling ": 10.527028446441618, "Juvenile idiopathic arthritis ": 17.825178915798027, "Laryngitis ": 12.485960102208224, "Leukopenia ": 2.056674393925776, "Lower respiratory tract infection ": 2.124087522405213, "Lymphocyte count decreased ": 3.422720480392464, "Mucous stools ": 21.005494902487907, "Musculoskeletal chest pain ": 4.726300449926645, "Musculoskeletal pain ": 2.3547135992354824, "Musculoskeletal stiffness ": 7.059125854719007, "Mycobacterium tuberculosis complex test positive ": 74.57893324652491, "Nasopharyngitis ": 2.397072080088689, "Neuropathy peripheral ": 2.043395218028026, "Nodule ": 4.696685871091507, "Normocytic anaemia ": 13.671963942845345, "Osteoarthritis ": 7.81704667384628, "Osteosclerosis ": 43.03121409068424, "Pancytopenia ": 2.0534196917129237, "Peripheral swelling ": 2.8898103802668995, "Pharyngeal swelling ": 2.4240670151370165, "Pigmentation disorder ": 11.889443453400656, "Pneumonitis ": 2.2903918331519293, "Polyarthritis ": 8.222074524367118, "Polyneuropathy ": 2.538510396295617, "Psoriasis ": 3.532014189991952, "Psoriatic arthropathy ": 13.375046521121352, "Pulmonary fibrosis ": 2.842033001405201, "Pulmonary toxicity ": 5.859949083856921, "Raynaud's phenomenon ": 6.078728777216509, "Red blood cell sedimentation rate increased ": 12.469854878167524, "Rheumatoid arthritis ": 13.263950877693098, "Rheumatoid nodule ": 22.93922105038044, "Seronegative arthritis ": 41.29968506120468, "Sinusitis ": 3.1230218728682204, "Sjogren's syndrome ": 11.65216857707072, "Skin lesion ": 2.3151985521192997, "Skin plaque ": 12.368737747488233, "Skin ulcer ": 2.883054350028196, "Suspected suicide ": 5.308265543540806, "Synovial cyst ": 12.2626082122909, "Synovitis ": 14.314795731591746, "Tendon disorder ": 10.059628227026568, "Tendonitis ": 3.6809391631386026, "Tenosynovitis ": 24.51529460698796, "Therapeutic product effect decreased ": 2.041337447852458, "Therapeutic product effect incomplete ": 2.7655217284640234, "Therapeutic response decreased ": 7.381814840207876, "Transaminases increased ": 2.040604695116417, "Treatment failure ": 3.3747016105962957, "Tuberculosis ": 6.595812314156319, "Upper respiratory tract infection ": 6.516649905179939, "White blood cell count abnormal ": 8.77558783836773, "White blood cell count decreased ": 2.102669778422348, "Wound ": 2.1858146496035933}
\ No newline at end of file
+{"Cough": 5.139943686023696, "Deafness": 48.54162470990339, "Dysphonia": 19.474822639182825, "Dyspnoea": 2.058224654261771, "Haemoptysis": 29.319983795503493, "Hospitalisation": 13.920478688864495, "Infective pulmonary exacerbation of cystic fibrosis": 159.55301259006828, "Off label use": 5.560801992169777, "Pneumonia": 4.2233570874079405, "Product dose omission issue": 8.72727438088926}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/65.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/65.json
index 3ad9238d3e3..33fd488be3a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/65.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/65.json
@@ -1 +1 @@
-{"Application site erythema ": 527.973245072209, "Application site exfoliation ": 1032.0127431283329, "Application site haemorrhage ": 428.25188660894895, "Application site oedema ": 406.4519230286784, "Application site pain ": 126.01282470419216, "Application site pruritus ": 78.91465391185146, "Application site pustules ": 1764.2703490542085, "Application site reaction ": 97.91933944061462, "Application site scab ": 4173.279286329315, "Application site swelling ": 252.3272667956982, "Application site vesicles ": 160.43156103925915, "Erythema ": 3.146547926884322, "Off label use ": 10.961417770735672, "Pain ": 2.400725791329203, "Skin reaction ": 85.10522020518985, "Skin tightness ": 91.4880189362023}
\ No newline at end of file
+{"Balance disorder": 40.79774938731653, "Blood calcium decreased": 312.51976967612313, "Cognitive disorder": 76.04273014064854, "Constipation": 20.514520952899133, "Creatinine renal clearance decreased": 394.00520379334097, "Depressed level of consciousness": 53.033409088262985, "Fall": 14.23487719334002, "Hypotension": 12.837664357602002, "Mobility decreased": 50.21150595409613, "Orthostatic hypotension": 119.58256281472892, "Pain": 4.720133398242711, "Sedation": 133.3674006465891, "Sedation complication": 426.37345282822974, "Toxicity to various agents": 18.03602615306352}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/650.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/650.json
index 35c0fb3dcc7..487c649dd61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/650.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/650.json
@@ -1 +1 @@
-{"Acute respiratory distress syndrome ": 2.14872331314692, "Alopecia areata ": 10.662728972050672, "Anti-thyroid antibody ": 139.0987784470424, "Anti-thyroid antibody positive ": 314.36001348904705, "Ataxia ": 2.821490732818384, "Autoimmune disorder ": 2.389570673242441, "Autoimmune haemolytic anaemia ": 18.53816870563779, "Autoimmune hepatitis ": 7.082509170389333, "Autoimmune hypothyroidism ": 50.51961394119918, "Autoimmune thyroid disorder ": 128.67900246225378, "Autoimmune thyroiditis ": 53.83191282055074, "Bladder disorder ": 3.2882341622141644, "Blood lactate dehydrogenase increased ": 2.3838021859965823, "Blood thyroid stimulating hormone abnormal ": 120.05676553153154, "Blood thyroid stimulating hormone decreased ": 82.58039876066874, "Blood thyroid stimulating hormone increased ": 21.87378383907581, "Blood urine present ": 3.8282215603305447, "Bradycardia ": 7.211005267683478, "C-reactive protein increased ": 5.296766845676344, "CD4 lymphocytes decreased ": 16.80288543521944, "Central nervous system lesion ": 17.33789541689722, "Cervical dysplasia ": 11.28652655035136, "Cholecystitis ": 5.913156135792227, "Cholecystitis acute ": 11.907234357870486, "Contusion ": 2.273657855535961, "Diplopia ": 2.3831548823992024, "Drug exposure before pregnancy ": 93.84634169618052, "Drug monitoring procedure not performed ": 46.96732077351384, "Endocrine ophthalmopathy ": 63.33927446755166, "Expanded disability status scale score increased ": 95.20882108715216, "Flushing ": 2.732428192494343, "Gait disturbance ": 2.2492963836956643, "Gingival bleeding ": 3.653696064266547, "Goitre ": 8.874795237480754, "Goodpasture's syndrome ": 162.17114345446225, "Graves' disease ": 126.5616172045172, "Haematocrit decreased ": 5.632492966493451, "Haemoglobin decreased ": 2.188195330914495, "Haemolytic anaemia ": 5.458240986614634, "Haemophagocytic lymphohistiocytosis ": 2.4605507148224097, "Haemoptysis ": 2.8027649736590625, "Heart rate abnormal ": 3.132716376214324, "Heart rate decreased ": 3.256731081357765, "Heart rate increased ": 2.1619200581816465, "Heart rate irregular ": 2.82218354066066, "Hemiparesis ": 3.0226481991745717, "Hyperthermia ": 3.8821894342295913, "Hyperthyroidism ": 30.24331914374539, "Hypothyroidism ": 8.927005992463785, "Immune thrombocytopenia ": 44.39309954496417, "Immunosuppression ": 4.519662278784796, "Incorrect drug administration rate ": 24.46263347946997, "Incorrect product administration duration ": 4.583118031605791, "Increased appetite ": 2.0815903969135383, "Laboratory test abnormal ": 3.621720089890224, "Leukopenia ": 2.3327519725294192, "Listeria sepsis ": 131.10689916181974, "Listeriosis ": 79.30399236280809, "Liver function test increased ": 2.0608254237839514, "Lymphocyte count abnormal ": 158.77695140779184, "Lymphocyte count decreased ": 33.57313614709771, "Lymphocyte percentage decreased ": 99.34423702853086, "Lymphopenia ": 28.243206903670345, "Magnetic resonance imaging abnormal ": 87.63845247378052, "Malignant melanoma ": 2.0770975811767176, "Mean cell haemoglobin decreased ": 27.158257191841624, "Mean cell volume decreased ": 16.24632739922808, "Mean cell volume increased ": 11.551232672526217, "Meningitis listeria ": 143.63200416987397, "Monocyte count decreased ": 38.051814173734186, "Monocyte percentage decreased ": 200.10094088166096, "Mood altered ": 2.3721595954009, "Motor dysfunction ": 2.301005739984688, "Multiple sclerosis ": 17.257764784611222, "Multiple sclerosis relapse ": 56.60979159502951, "Muscle spasticity ": 5.679675875144048, "Muscular weakness ": 2.1324915017030937, "Neutrophil count abnormal ": 21.751065209396163, "Neutrophil count increased ": 10.015330921787124, "Neutrophil percentage increased ": 60.84889620006983, "Optic neuritis ": 5.323278433489317, "Paraparesis ": 11.096144810247372, "Petechiae ": 6.096998294941883, "Platelet count abnormal ": 17.11617574383416, "Platelet count decreased ": 4.016873737372585, "Pneumonitis ": 3.757755789756212, "Pregnancy ": 3.202600017487929, "Procalcitonin increased ": 18.29954473561047, "Progressive multifocal leukoencephalopathy ": 6.967018618871005, "Protein urine present ": 8.54560810210846, "Proteinuria ": 2.271459153916815, "Pulmonary alveolar haemorrhage ": 4.657545623267093, "Quadriplegia ": 7.709749894427327, "Rash ": 3.181336883524734, "Rash pruritic ": 3.209032709943617, "Red blood cell count decreased ": 3.370313038324932, "Red blood cells urine positive ": 46.67278921735836, "Red cell distribution width increased ": 9.218522099819216, "Sinus bradycardia ": 6.045703948241426, "Splenomegaly ": 2.048809668767644, "T-lymphocyte count decreased ": 50.23150163508888, "Temperature intolerance ": 14.926050538212602, "Thrombocytopenia ": 2.0969302628177644, "Thrombotic thrombocytopenic purpura ": 4.93918847614319, "Thyroid cancer ": 4.485956921005423, "Thyroid disorder ": 16.259927877650952, "Thyroid function test abnormal ": 21.82213989680832, "Thyroid hormones increased ": 23.09919146269037, "Thyroid mass ": 5.4845458589740215, "Thyroid stimulating immunoglobulin ": 1034.1950151487952, "Thyroidectomy ": 20.33452135401629, "Thyroiditis ": 16.653037045645465, "Thyroiditis subacute ": 12.853466586254806, "Thyroxine decreased ": 55.71555832429561, "Thyroxine free abnormal ": 302.5200800878616, "Thyroxine free decreased ": 57.15881881817646, "Thyroxine free increased ": 63.994883888, "Thyroxine increased ": 71.32546412355751, "Tri-iodothyronine free increased ": 105.4814836629793, "Tri-iodothyronine increased ": 79.89454199002692, "Tuberculosis ": 2.0179068586295537, "Type 1 diabetes mellitus ": 2.680401902852073, "Unevaluable event ": 3.5096739426359003, "Urinary sediment present ": 56.50905027710078, "Urinary tract infection ": 3.334893715605236, "Vitiligo ": 11.13938739947966, "White blood cell count abnormal ": 9.3182022126485, "White blood cell count increased ": 3.9596133054999454, "White blood cells urine positive ": 25.18015973754559}
\ No newline at end of file
+{"Abortion induced": 7.052488303638123, "Abortion spontaneous": 2.324682801906542, "Acidosis": 4.607419543616195, "Acquired gene mutation": 33.238896139176376, "Acute hepatic failure": 11.273679665831851, "Acute respiratory failure": 3.186311737475385, "Alanine aminotransferase increased": 2.064056259812392, "Anaemia": 2.307640542166929, "Anion gap increased": 32.785953755349425, "Aphthous ulcer": 3.518316360843172, "Ascites": 3.254510077463169, "Atrioventricular block complete": 4.485437309553661, "Blood HIV RNA increased": 44.768193447434825, "Blood alkaline phosphatase increased": 2.0771486282320777, "Blood bilirubin increased": 2.4118946503528287, "Blood lactic acid increased": 18.976647894607986, "Blood triglycerides increased": 2.870412780134394, "Bronchial hyperreactivity": 32.69532221930547, "CD4 lymphocytes decreased": 43.354955896552994, "CD4 lymphocytes increased": 261.3801588479279, "CSF HIV escape syndrome": 130.4136955617939, "Cachexia": 7.106099736861508, "Cardiac murmur": 5.138688176925462, "Cardiomyopathy": 3.812885749307082, "Central nervous system lesion": 9.040011859027077, "Cervical dysplasia": 17.016252262998087, "Clavicle fracture": 12.020634184707609, "Coagulopathy": 2.989894582463382, "Conjunctivitis": 2.0377013114823663, "Cryptococcosis": 67.57234709249312, "Cytomegalovirus infection": 4.344323192341329, "Dermatitis exfoliative": 8.587223678650858, "Developmental delay": 9.99744183568796, "Dilated cardiomyopathy": 9.535679925356042, "Disseminated intravascular coagulation": 2.933873924414, "Disseminated tuberculosis": 22.91546804222777, "Drug resistance": 10.233656324555149, "Drug-induced liver injury": 2.613136382357826, "Encephalitis": 3.4205823407608933, "Encephalopathy": 2.128890292933612, "Exposure during pregnancy": 3.5717122455914927, "Failure to thrive": 11.808773758426742, "Foetal death": 4.398106692919867, "Foetal exposure during pregnancy": 9.90235945375504, "Gamma-glutamyltransferase increased": 2.071123211880536, "Granuloma": 10.70561463647167, "HIV infection": 84.26817768120603, "HIV-associated neurocognitive disorder": 120.47572943055047, "Hepatic cirrhosis": 2.423112709854484, "Hepatic encephalopathy": 11.26171137728526, "Hepatic failure": 8.14290679146103, "Hepatic function abnormal": 2.688355880050378, "Hepatic steatosis": 4.955490336452736, "Hepatitis": 3.5392965537070853, "Hepatitis B": 23.88655440692921, "Hepatitis B reactivation": 30.03203632840066, "Hepatomegaly": 24.622710880008647, "Hepatosplenomegaly": 35.059602296950295, "Hepatotoxicity": 7.983379440648861, "Hyperbilirubinaemia": 3.627244885292161, "Hypercholesterolaemia": 10.348829177875848, "Hyperlactacidaemia": 26.679554344313985, "Hypertriglyceridaemia": 16.378838925631023, "Hypoalbuminaemia": 11.400843057685156, "Immune reconstitution inflammatory syndrome": 240.4610028291607, "Injection site ulcer": 37.96669611181628, "Intracranial pressure increased": 8.50540643702899, "Jaundice": 7.19710398418993, "Joint dislocation": 7.401791026363712, "Kaposi's sarcoma": 22.47138384422397, "Lactic acidosis": 11.65414318888806, "Leprosy": 201.357822559237, "Lipoatrophy": 43.77061911694503, "Lipodystrophy acquired": 23.014576515920773, "Live birth": 6.563415513755155, "Liver function test abnormal": 3.989939901651817, "Liver injury": 5.951574222691468, "Low birth weight baby": 6.447978394621438, "Low set ears": 70.34112268644077, "Lung infiltration": 6.108716639535079, "Lymphadenitis": 23.85275776010846, "Macrocytosis": 30.990901072345288, "Maternal exposure during pregnancy": 2.054066480569113, "Meningitis cryptococcal": 108.48959861935464, "Metabolic acidosis": 5.42732983525791, "Mitochondrial toxicity": 45.18824138855129, "Molluscum contagiosum": 209.13265569696145, "Mouth ulceration": 2.092034122131244, "Multiple-drug resistance": 6.862826082977011, "Muscle spasticity": 4.274967737306327, "Mycobacterial infection": 38.404652003389984, "Mycobacterium avium complex infection": 19.15581025306196, "Nephropathy toxic": 4.099949308267737, "Nephrotic syndrome": 5.450446214539015, "Neuropathy peripheral": 4.928953105381245, "Nodular regenerative hyperplasia": 98.9965773969692, "Oedema": 2.3110925618244105, "Oral candidiasis": 2.0457059839534777, "Pallor": 2.711199273099341, "Pancreatitis": 2.1340268536953126, "Pancytopenia": 2.6711823353871, "Papule": 4.64319458223776, "Pathogen resistance": 26.15368890218628, "Peripheral ischaemia": 9.199746292940432, "Pneumocystis jirovecii pneumonia": 4.145989802783515, "Polyneuropathy": 2.8258993565133608, "Portal hypertension": 19.0316419296194, "Pregnancy": 8.208890626529648, "Premature baby": 5.498225871974321, "Premature delivery": 3.7358090888459534, "Progressive multifocal leukoencephalopathy": 14.334710120202152, "Proteinuria": 4.448180624175497, "Pulmonary tuberculosis": 11.216014152130064, "Rash maculo-papular": 2.3873286857142832, "Respiratory distress": 2.346521605900777, "Skin lesion": 9.466962784844132, "Skin mass": 6.266463227898819, "Skin ulcer": 2.3569622858840864, "Small for dates baby": 14.663332322560398, "Splenomegaly": 7.7809052219685775, "Stevens-Johnson syndrome": 6.610783681243444, "Stillbirth": 19.76986616190751, "Tachypnoea": 3.9064763703618426, "Thrombotic microangiopathy": 4.217252247993341, "Toxic epidermal necrolysis": 5.688526498137124, "Treatment failure": 6.494508487398591, "Treatment noncompliance": 4.319787513504023, "Trisomy 21": 52.8840389702044, "Tuberculoid leprosy": 495.5222310372432, "Tuberculosis": 18.855335508012224, "Viral load increased": 8.295727128053338, "Viral mutation identified": 118.0984434626281, "Virologic failure": 70.34159354173681, "Visual acuity reduced": 2.25264336248127}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/651.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/651.json
index ea5fdf1506e..51ebbfa3ef9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/651.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/651.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.1968264592693223, "Blood lactate dehydrogenase increased ": 8.256050239808985, "Cytokine release syndrome ": 7.979222337271628, "Cytopenia ": 13.47495918984489, "Diffuse large B-cell lymphoma ": 28.33090821670304, "Disease progression ": 17.15449841735862, "Febrile neutropenia ": 12.201021266757577, "Follicular lymphoma ": 145.17564843664542, "Infection ": 3.173961515205887, "Intentional product use issue ": 2.9335982464945336, "Malignant neoplasm progression ": 3.256936199165221, "Myelodysplastic syndrome ": 13.058060614436116, "Myelosuppression ": 10.146210653105106, "Neoplasm progression ": 4.284263797224767, "Neuropathy peripheral ": 2.5465568397602976, "Neutropenia ": 8.140339648451084, "Neutrophil count abnormal ": 82.10552000916098, "Neutrophil count decreased ": 6.0210835035711, "Off label use ": 6.297644749552972, "Plasma cell myeloma ": 15.03797815831158, "Platelet count abnormal ": 51.36176312677823, "Platelet count decreased ": 5.561125391079474, "Platelet disorder ": 160.24766203663197, "Pneumonia ": 4.173327347810318, "Rash maculo-papular ": 3.298335783450171, "Rash pruritic ": 2.6446630610189907, "Renal impairment ": 2.328058099474018, "Thrombocytopenia ": 4.261664046664009, "White blood cell count decreased ": 5.487689980223721}
\ No newline at end of file
+{"Abdominal hernia": 2.3554896944164314, "Abdominal infection": 2.800649591573717, "Abdominal operation": 4.285590890932472, "Accident": 2.68532837716594, "Accidental overdose": 2.804037901729704, "Adverse reaction": 5.155905148734833, "Age-related macular degeneration": 3.054767582525908, "Amputation": 9.557989664770307, "Amyloidosis": 4.11899299092068, "Angiopathy": 3.0126645323533814, "Angioplasty": 3.134459951723984, "Ankle fracture": 3.02007218868058, "Anti-insulin antibody increased": 11.482415684585735, "Anti-insulin antibody positive": 35.353705355060434, "Aortic valve replacement": 3.091001306575436, "Application site haemorrhage": 2.942659601520447, "Arterial occlusive disease": 3.07047876277982, "Back disorder": 5.18016305207393, "Bedridden": 2.9810114919536, "Blindness": 9.948749887007818, "Blindness unilateral": 9.289349879820826, "Blood glucose abnormal": 21.267013869898182, "Blood glucose decreased": 32.56041126892916, "Blood glucose fluctuation": 33.10135155632118, "Blood glucose increased": 26.238212568970813, "Blood insulin increased": 5.649544679426209, "Blood ketone body": 15.973194088214909, "Blood ketone body increased": 5.025465257723556, "Blood potassium abnormal": 2.042017731073916, "Brain neoplasm": 2.466746429833496, "Brain neoplasm malignant": 2.4748088912394333, "Cardiac disorder": 4.061948201118551, "Cardiac failure congestive": 2.4307727958125493, "Cardiac operation": 13.575710761140618, "Cardiac pacemaker insertion": 4.281319998990235, "Carotid artery occlusion": 2.0809819483096037, "Carpal tunnel decompression": 7.631678656191119, "Carpal tunnel syndrome": 2.3043445127288296, "Cartilage injury": 3.403464685723955, "Cataract": 17.612476272839668, "Cataract operation": 29.512634249087387, "Catheter placement": 2.012724051467617, "Catheterisation cardiac": 2.1533329146416773, "Cerebrovascular accident": 5.316230468229178, "Cervical vertebral fracture": 2.0407506765239884, "Cold sweat": 3.2402116853828784, "Colon cancer": 2.6897770000763117, "Colour blindness": 2.510365313843642, "Concussion": 3.592900332394989, "Corneal disorder": 2.036614968256369, "Corneal transplant": 10.779527465946336, "Coronary arterial stent insertion": 2.8973621421679736, "Coronary artery bypass": 7.961728683725709, "Coronary artery occlusion": 3.247733509403814, "Corrective lens user": 12.103119653304766, "Craniocerebral injury": 2.5789187206999284, "Cutaneous amyloidosis": 43.80142730973982, "Dawn phenomenon": 18.77320171749247, "Decubitus ulcer": 2.2906359323148293, "Dementia": 6.567366356572887, "Dementia Alzheimer's type": 9.257704216671636, "Device breakage": 8.739905254051013, "Device defective": 9.420284638780222, "Device delivery system issue": 7.268399878196354, "Device ineffective": 4.119975245705015, "Device issue": 22.43784681854332, "Device leakage": 3.886989024072257, "Device malfunction": 31.86366459125246, "Device mechanical issue": 10.136513735531986, "Device operational issue": 181.94847243749783, "Device use issue": 10.727291029827503, "Diabetes mellitus inadequate control": 34.88072388199223, "Diabetic coma": 19.47825748209545, "Diabetic complication": 15.236667187704, "Diabetic eye disease": 11.683414066951183, "Diabetic foot": 14.294896994504413, "Diabetic foot infection": 5.339330076431342, "Diabetic hyperglycaemic coma": 38.24427610250972, "Diabetic ketoacidosis": 7.140274082965632, "Diabetic ketosis": 2.683545717253401, "Diabetic metabolic decompensation": 14.863591503311014, "Diabetic nephropathy": 8.231134539903845, "Diabetic neuropathy": 12.524824769019167, "Diabetic retinal oedema": 7.864202723299691, "Diabetic retinopathy": 36.31565971121873, "Dialysis": 9.39108113608843, "Diet noncompliance": 18.55163812371005, "Disability": 14.961341153306725, "Disease complication": 3.333628785980831, "Drug dose omission by device": 3.3366776509454046, "Dysgraphia": 2.399949797404464, "Exercise lack of": 9.156209584204955, "Expired device used": 30.083697025656587, "Expired product administered": 6.526913072197282, "Extra dose administered": 3.7019075759991886, "Extremity necrosis": 2.736652941003308, "Eye disorder": 7.314088836733189, "Eye haemorrhage": 8.693643771959087, "Eye infection": 2.51236302896192, "Eye injury": 2.05895539903638, "Eye laser surgery": 19.88411647407262, "Eye operation": 18.480510826475577, "Fall": 2.846395524092505, "Fat tissue increased": 4.102007307930167, "Feeling abnormal": 2.016120445457076, "Femur fracture": 2.066539056259168, "Foetal chromosome abnormality": 14.37343277918957, "Foetal exposure timing unspecified": 11.48803935466787, "Food poisoning": 2.303434450714469, "Foot amputation": 32.16234642593302, "Foot fracture": 2.6964894633586383, "Foot operation": 8.161798943910071, "Foreign body": 10.112010268024688, "Fractured coccyx": 3.616486077161892, "Frustration tolerance decreased": 2.051561823295374, "Gallbladder disorder": 3.966729306889741, "Gallbladder operation": 5.66741933240526, "Gangrene": 5.498441057008426, "Gastrointestinal carcinoma": 2.40890757089265, "Glaucoma": 7.999546670658191, "Glycosylated haemoglobin abnormal": 19.27820567004624, "Glycosylated haemoglobin decreased": 9.098572941901336, "Glycosylated haemoglobin increased": 22.414038697485747, "Granuloma annulare": 3.131577575270952, "Haemodialysis": 2.729121913640665, "Heart transplant": 5.982948142146345, "Heart valve replacement": 8.501225370967846, "Hepatic neoplasm": 4.419789336106967, "Hernia repair": 4.789334890544276, "Hip fracture": 2.5773849089847944, "Hip surgery": 2.4648399291029097, "Hospitalisation": 6.643118912032518, "Hunger": 7.104193484273528, "Hyperbilirubinaemia neonatal": 5.982948142146345, "Hyperglycaemia": 37.91984440578185, "Hyperglycaemic unconsciousness": 33.81493925125257, "Hyperhidrosis": 2.5935392602328324, "Hyperinsulinaemia": 5.084400336758828, "Hyperinsulinaemic hypoglycaemia": 35.517962690977825, "Hypoacusis": 3.906283847827712, "Hypoglycaemia": 35.503161697491976, "Hypoglycaemia neonatal": 10.928390424758552, "Hypoglycaemia unawareness": 23.61632044948392, "Hypoglycaemic coma": 32.33117007941675, "Hypoglycaemic encephalopathy": 12.699282658650931, "Hypoglycaemic seizure": 76.27029598531811, "Hypoglycaemic unconsciousness": 70.97612271210569, "Impaired gastric emptying": 2.2462797152407137, "Inappropriate schedule of product administration": 4.077153788400355, "Incoherent": 3.9821989219914378, "Incorrect dosage administered": 2.186681001019407, "Incorrect dose administered": 2.9442821916908883, "Incorrect dose administered by device": 15.015294149363324, "Infarction": 4.60509320735576, "Infected skin ulcer": 3.272176082716209, "Injection site atrophy": 7.505546131366235, "Injection site bruising": 8.493984898905378, "Injection site discolouration": 10.296856272706036, "Injection site extravasation": 6.496222642995168, "Injection site haemorrhage": 13.883980830812169, "Injection site infection": 3.2610596989295337, "Injection site injury": 11.465413385743068, "Injection site irritation": 2.877395063931004, "Injection site mass": 4.138530758909317, "Injection site nodule": 6.113096633344028, "Injection site scar": 7.296281495093635, "Injection site ulcer": 2.684951090862003, "Injury associated with device": 11.232996585754025, "Insulin autoimmune syndrome": 4.587366454375105, "Insulin resistance": 7.142940633250903, "Intentional dose omission": 3.724546173085043, "Intercepted medication error": 8.891909490135637, "Intervertebral disc disorder": 2.3255915458252674, "Intervertebral disc protrusion": 3.461171331460984, "Jaundice neonatal": 2.950018263934024, "Joint injury": 2.4033149759038936, "Ketoacidosis": 9.2000146299674, "Ketonuria": 7.680777469378942, "Ketosis": 10.196723116313391, "Kidney infection": 2.634478307225094, "Knee arthroplasty": 3.1919786356234447, "Knee operation": 5.001069522119328, "Lack of injection site rotation": 31.080996656631854, "Laryngeal cancer": 3.934631118869082, "Laziness": 8.266097074802442, "Leg amputation": 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"Neoplasm": 2.5713935091488533, "Neoplasm malignant": 3.128526128821905, "Nervousness": 3.189269334790811, "Neuropathic arthropathy": 7.403753378594509, "Ocular vascular disorder": 3.721179044518842, "Oesophageal carcinoma recurrent": 90.23988747741272, "Osteomyelitis": 3.1300887689700474, "Pancreatectomy": 4.743813495588173, "Pancreatic carcinoma": 2.206690370942671, "Pancreatic disorder": 8.72538235220352, "Pancreatic failure": 2.819457184178765, "Pancreatic neoplasm": 2.942659601520447, "Parkinson's disease": 3.0700704366690013, "Pituitary tumour": 2.705860199789325, "Pollakiuria": 2.0079664838588416, "Poor peripheral circulation": 3.076475009273464, "Postoperative wound infection": 2.0365265190624977, "Pre-eclampsia": 2.118410752769286, "Product administration error": 12.106435728373285, "Product complaint": 15.814757523840088, "Product counterfeit": 4.233143513894837, "Product dose omission issue": 3.463389509798243, "Product odour abnormal": 3.2669705433776577, "Product prescribing issue": 2.644605056816834, "Product quality issue": 3.993131680677228, "Product storage error": 32.010403793027145, "Product use issue": 4.266326936749742, "Prostatic operation": 6.061922734849496, "Rectal tenesmus": 3.1311924691670328, "Renal disorder": 5.357850886776788, "Renal mass": 2.236584808133062, "Renal neoplasm": 2.0469751060077703, "Renal transplant": 19.756297126474763, "Retinal detachment": 6.718018692208738, "Retinal disorder": 12.23238895315426, "Retinal haemorrhage": 6.27677733383914, "Retinal injury": 6.2988308178496215, "Retinopathy": 18.3633913329524, "Retinopathy proliferative": 20.9942897144762, "Road traffic accident": 4.270213203043893, "Rotator cuff repair": 6.821847291870877, "Rotator cuff syndrome": 2.372395043643021, "Sciatic nerve injury": 4.982039519207997, "Shock hypoglycaemic": 20.47479592133686, "Shoulder arthroplasty": 2.659774373648379, "Shoulder fracture": 3.4900448677122653, "Shoulder operation": 4.958014828299831, "Silent myocardial infarction": 6.324984957605673, "Skin ulcer": 2.46715417066791, "Sluggishness": 3.8629929226574222, "Sopor": 3.5174702370828723, "Speech disorder": 2.1144981436221566, "Spinal cord injury": 2.157110466041207, "Spinal disorder": 3.4330827175385883, "Spinal operation": 6.268287497903515, "Staphylococcal infection": 2.227977083333554, "Stent placement": 4.091601815693234, "Surgery": 4.0725744943936775, "Suspected counterfeit product": 2.5530011373603725, "Suspected product quality issue": 3.027255000312526, "Therapeutic product ineffective": 2.1525287536454183, "Thirst": 2.5292985840013924, "Throat cancer": 2.446852851722716, "Thyroid cancer": 2.114836678926606, "Toe amputation": 22.55587039316186, "Trigger finger": 2.5505512330981923, "Unevaluable event": 5.221921925664985, "Upper limb fracture": 3.1844174605830267, "Urinary tract infection": 2.062540125162549, "Urine ketone body present": 7.595116202992573, "Vascular dementia": 4.798553354654567, "Vascular graft": 16.098689385265146, "Vascular occlusion": 5.372307977126477, "Venous occlusion": 2.7411253676274194, "Vision blurred": 2.247355971637016, "Visual impairment": 8.794718945434406, "Vitreous disorder": 4.320797211953483, "Vitreous haemorrhage": 11.539529861265088, "Walking aid user": 7.077326338202556, "Weight increased": 2.866972477784772, "Wheelchair user": 12.949701924312976, "Wrist fracture": 2.320442188309193, "Wrong device used": 21.30966947723932, "Wrong product administered": 7.689194607741006, "Wrong technique in device usage process": 12.03046236401724, "Wrong technique in product usage process": 3.0798549617291253}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/652.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/652.json
index c0a27c3d83b..95c2127e50e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/652.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/652.json
@@ -1 +1 @@
-{"Decreased appetite ": 2.591570654186314, "Hypertension ": 4.255357620400849, "Malignant neoplasm progression ": 10.076448626612216, "Palmar-plantar erythrodysaesthesia syndrome ": 21.372306069844967, "Product use in unapproved indication ": 4.71814602364193}
\ No newline at end of file
+{"Intraocular pressure increased": 308.75645539874336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/653.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/653.json
index 31e28529c3a..35411e040df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/653.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/653.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 8.930942728376815, "Altered state of consciousness ": 2.4799665845552, "Ammonia increased ": 39.94253449630861, "Aortic dissection ": 20.651641066753616, "Arterial haemorrhage ": 34.065267325009586, "Ascites ": 11.947432428003705, "Aspartate aminotransferase increased ": 2.3196194220935644, "Blood albumin decreased ": 10.562859355633238, "Blood bilirubin increased ": 5.396399218810838, "Blood pressure increased ": 3.8734521482711983, "Blood thyroid stimulating hormone increased ": 14.456303508549514, "C-reactive protein increased ": 4.443000622909988, "Cardiac failure ": 4.314171500666581, "Cardiomyopathy ": 2.9012502879927835, "Cerebral haemorrhage ": 5.19294244221353, "Cerebral infarction ": 6.638697528789071, "Cholangitis ": 31.238836287333168, "Cholecystitis ": 23.69378658833244, "Cholecystitis acute ": 20.976946497177167, "Colitis ": 2.12685117337769, "Decreased appetite ": 11.40617200196008, "Dehydration ": 2.9445790959199454, "Diarrhoea ": 3.537950666911017, "Disseminated intravascular coagulation ": 2.846569099635216, "Drug eruption ": 2.1347704191464043, "Duodenal perforation ": 42.479587530942695, "Duodenal ulcer ": 4.282201277694157, "Duodenal ulcer haemorrhage ": 8.061933411146926, "Dysphonia ": 7.856109076067763, "Ejection fraction decreased ": 4.071966007755188, "Electrolyte imbalance ": 2.8846279584939047, "Encephalopathy ": 3.02890357611472, "Female genital tract fistula ": 4.233363004187082, "Fistula ": 31.70052200738032, "Gastric haemorrhage ": 2.6897151412464675, "Gastrointestinal perforation ": 40.12790119771768, "Generalised oedema ": 2.045157432292528, "Gingivitis ": 4.872605574255534, "Haematemesis ": 2.762349110647884, "Haemobilia ": 47.64103992779931, "Haemoptysis ": 4.824375820268939, "Hepatic encephalopathy ": 128.29548863085378, "Hepatic failure ": 8.739479561409487, "Hepatic function abnormal ": 5.5269270061868045, "Hyperaesthesia ": 6.203625348806715, "Hyperammonaemia ": 11.82633170608136, "Hypercalcaemia ": 2.2987456275342466, "Hypertension ": 13.802416264708938, "Hypertensive crisis ": 6.008694766639326, "Hyperthyroidism ": 2.9696860269319623, "Hypoalbuminaemia ": 4.647739014787701, "Hypocalcaemia ": 3.827131628437941, "Hypothyroidism ": 18.639165602739286, "Impaired healing ": 3.640410868017765, "Interstitial lung disease ": 4.972714864401161, "Intestinal perforation ": 11.51869585128959, "Jaundice ": 3.657477694873463, "Large intestine perforation ": 11.66486718706894, "Liver abscess ": 13.400039871420544, "Liver carcinoma ruptured ": 271.07394042044467, "Liver disorder ": 4.174418119128023, "Malignant neoplasm progression ": 7.298647799365376, "Mucosal inflammation ": 6.065694936931237, "Nephrotic syndrome ": 15.119008861741564, "Neutrophil count decreased ": 2.076983816420066, "Oedema ": 2.619798012002812, "Oedema peripheral ": 2.122636973033883, "Oesophageal varices haemorrhage ": 45.64002112013237, "Osteonecrosis of jaw ": 7.223543500335463, "Palmar-plantar erythrodysaesthesia syndrome ": 31.71208721746813, "Peritonitis ": 2.652979241113815, "Platelet count decreased ": 8.30307116506572, "Pleural effusion ": 2.925435608422407, "Pneumatosis intestinalis ": 12.528553601031517, "Pneumonia aspiration ": 2.722133455250781, "Pneumothorax ": 10.744055730438356, "Polycythaemia ": 27.482390398199648, "Portal vein thrombosis ": 16.95733373696746, "Posterior reversible encephalopathy syndrome ": 12.24705296816257, "Protein urine present ": 22.02907929843787, "Proteinuria ": 62.09274455717696, "Renal impairment ": 2.8982816678613945, "Skin ulcer ": 3.817334753552463, "Small intestinal perforation ": 26.649858926258048, "Stomatitis ": 6.3551049915749855, "Thyroiditis ": 6.217118023287381, "Tracheal fistula ": 526.8247248548116, "Transaminases increased ": 2.0898667479272723, "Tumour haemorrhage ": 84.89722879375826, "Tumour lysis syndrome ": 22.158735252069334, "Tumour rupture ": 53.60569918896044, "Upper gastrointestinal haemorrhage ": 2.0740997562694945, "Weight decreased ": 3.4954101867392464}
\ No newline at end of file
+{"Abnormal behaviour": 7.180708771614565, "Abulia": 14.08647118210864, "Activation syndrome": 91.89019179892796, "Affective disorder": 5.976906178180464, "Aggression": 6.252346600649236, "Agitation": 4.095702196641973, "Akathisia": 50.277405798980354, "Anger": 13.500701450748942, "Anxiety": 3.307393947750888, "Apathy": 4.918695597125134, "Autism spectrum disorder": 4.739382727609009, "Aversion": 58.86945696779946, "Bipolar I disorder": 32.33995462696452, "Bipolar disorder": 57.76609162170238, "Blepharospasm": 3.237365173149017, "Blood prolactin increased": 26.334610390357557, "Blood triglycerides increased": 2.547497133082527, "Blunted affect": 30.981787930057248, "Bradyphrenia": 3.042817636044981, "Brain injury": 3.477766499593059, "Bruxism": 17.753558010888593, "Catatonia": 13.731708102417722, "Cognitive disorder": 2.251336355519759, "Cogwheel rigidity": 19.781820449664394, "Completed suicide": 3.998016621997286, "Crying": 5.782061130491279, "Decreased activity": 3.881731015195834, "Delusion": 18.190018083578504, "Depressed mood": 4.72369524387399, "Depression": 5.1761089234389415, "Depressive symptom": 8.108743596904244, "Diabetes mellitus": 2.2540518432200427, "Drooling": 10.254229855473769, "Drug effective for unapproved indication": 9.497261143728627, "Drug ineffective for unapproved indication": 5.112215333049673, "Dysarthria": 2.317266486983779, "Dyskinesia": 12.065524896485076, "Dysphemia": 5.721153603028377, "Dystonia": 43.07225106585189, "Emotional disorder": 2.8932844919848923, "Emotional poverty": 13.5690236058716, "Energy increased": 13.99529255170698, "Erectile dysfunction": 4.246022239549406, "Euphoric mood": 4.098198385265858, "Extra dose administered": 2.005714666111704, "Extrapyramidal disorder": 16.212708043419088, "Eye movement disorder": 2.780552109262024, "Fear": 7.643842398239859, "Feeling abnormal": 4.795412589965945, "Feeling jittery": 4.893955864089135, "Feeling of despair": 10.379118698451762, "Flat affect": 17.755906768969258, "Frustration tolerance decreased": 5.47558127092253, "Galactorrhoea": 11.607195555130296, "Gastric bypass": 30.53803614419454, "Gestational diabetes": 5.311467690673049, "Hallucination": 4.676230114320489, "Hallucination, auditory": 30.601852506935607, "Hallucination, visual": 3.087308699109023, "Head injury": 2.049495255294012, "Homicidal ideation": 14.177840724623346, "Hostility": 10.946057070999917, "Hyperprolactinaemia": 51.74356191240668, "Hypersomnia": 2.4351623363602144, "Hyperventilation": 3.0548652769830373, "Hypomania": 8.795684790603806, "Impulsive behaviour": 12.267298597575476, "Increased appetite": 7.884965215555664, "Initial insomnia": 2.301809176501264, "Insomnia": 3.4342148837405047, "Intentional dose omission": 4.296082312664163, "Intentional self-injury": 8.39948755539375, "Irritability": 3.5465622224739874, "Logorrhoea": 8.188355011155997, "Major depression": 10.670326275528408, "Malabsorption": 2.478510551521283, "Mania": 36.81915325790826, "Mental disorder": 6.165308565013028, "Mental impairment": 5.767121979839229, "Metabolic surgery": 20.2521963370098, "Middle insomnia": 2.0868334972548768, "Mood altered": 4.688870847023732, "Mood swings": 6.207860266090219, "Muscle rigidity": 6.943846111455374, "Musculoskeletal stiffness": 2.049140616977808, "Near death experience": 4.683636252556969, "Negative thoughts": 12.210437613776168, "Nervousness": 2.082205177468173, "Neuroleptic malignant syndrome": 11.85959994627396, "Nightmare": 2.063048762003044, "Obesity": 4.261541041772467, "Obsessive thoughts": 19.337806689170385, "Obsessive-compulsive disorder": 4.327155416712492, "Oculogyric crisis": 89.49644459543752, "Off label use": 5.092642228113919, "Oromandibular dystonia": 41.06326569656673, "Panic attack": 6.119671745237946, "Panic reaction": 3.1106919729643723, "Paranoia": 13.471220864343618, "Parkinson's disease": 3.670973563437508, "Parkinsonism": 10.460422764586962, "Persecutory delusion": 11.349998166176958, "Personality change": 2.784330587886993, "Physical assault": 13.267118074208542, "Physical deconditioning": 3.953999088860821, "Pneumonia aspiration": 2.0572458510186435, "Polydipsia": 9.138487424797011, "Poor quality sleep": 2.4843087966396897, "Post-traumatic stress disorder": 15.111620668454814, "Pregnancy": 11.366393886709735, "Prescribed overdose": 4.176899015217927, "Prescribed underdose": 26.845203589340443, "Product administered to patient of inappropriate age": 5.531422011277158, "Product administration error": 6.973960736260638, "Product dose omission issue": 2.319771403414354, "Product use in unapproved indication": 2.1191594548135377, "Psychiatric decompensation": 8.074227299509102, "Psychiatric symptom": 15.73146219237784, "Psychomotor hyperactivity": 5.5265487070963255, "Psychotic disorder": 10.779290717492495, "Psychotic symptom": 37.1786391081467, "Restless legs syndrome": 5.713083208448298, "Restlessness": 8.107327859828523, "Road traffic accident": 2.295264592706149, "Salivary hypersecretion": 6.848068361054468, "Schizoaffective disorder": 19.77172888196404, "Schizophrenia": 37.88318525932536, "Screaming": 6.0883371726773685, "Sedation": 3.95296038508841, "Sedation complication": 3.336596807987536, "Seizure": 2.06208767711229, "Self-destructive behaviour": 15.265871679827743, "Self-injurious ideation": 25.60733161160183, "Serotonin syndrome": 2.6108654168673247, "Sleep apnoea syndrome": 2.117410195905879, "Social avoidant behaviour": 6.315277835281716, "Soliloquy": 22.695998013031364, "Somnambulism": 5.197930357832098, "Somnolence": 2.180915085862267, "Speech disorder": 2.904407322262264, "Stress": 2.730203913937683, "Suicidal behaviour": 12.417734567667315, "Suicidal ideation": 26.10870667323299, "Suicide attempt": 6.126282653605212, "Swollen tongue": 3.63075821030564, "Tachyphrenia": 31.770158734798905, "Tardive dyskinesia": 107.3720914635213, "Temperature intolerance": 2.642258719239546, "Therapeutic response decreased": 2.0228410513480406, "Therapeutic response unexpected": 3.0705175838565784, "Therapy cessation": 33.821684600323465, "Therapy interrupted": 34.15821001601951, "Thinking abnormal": 7.239894630544351, "Tic": 6.425829670251649, "Tongue movement disturbance": 25.67288451600384, "Torticollis": 11.176071403279094, "Treatment noncompliance": 3.0342293954792225, "Tremor": 3.2007865933310784, "Trismus": 10.586490390139504, "Underdose": 3.113041601358661, "Urinary incontinence": 2.102421555931233, "Urinary retention": 3.586005534046205, "Violence-related symptom": 10.704638481319, "Weight increased": 6.031952881055004, "Withdrawal syndrome": 3.3743231697275164, "Wrong technique in product usage process": 4.8387584713696965}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/654.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/654.json
index 164fd6d1e82..c0d98bd7466 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/654.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/654.json
@@ -1 +1 @@
-{"Myalgia ": 3.369100339840505}
\ No newline at end of file
+{"Completed suicide": 27.82921476166062, "Death": 14.433444390086231}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/655.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/655.json
index 34dc22f7449..7a7ffe013a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/655.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/655.json
@@ -1 +1 @@
-{"Hot flush ": 15.19712763704767, "Malignant neoplasm progression ": 8.509482013205686, "Prostate cancer ": 46.12833308098613, "Prostatic specific antigen increased ": 233.6534224817427}
\ No newline at end of file
+{"Drug ineffective": 2.8711881479723877, "Drug interaction": 19.470729618646136, "Hepatitis C": 39.02832528485297, "Treatment failure": 17.78295435024443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/656.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/656.json
index e66f54af7c3..28cde0ac3c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/656.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/656.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 6.708010821351965, "Accident ": 2.2698265090541785, "Accidental overdose ": 2.731468809454636, "Anti-insulin antibody ": 60.51446007654668, "Anti-insulin antibody increased ": 42.24135693190912, "Anti-insulin antibody positive ": 65.54256120743777, "Arterial occlusive disease ": 4.452209429941644, "Blindness ": 4.996811570925369, "Blindness unilateral ": 5.340982813071396, "Blood glucose abnormal ": 15.898193397272356, "Blood glucose decreased ": 29.189055914170343, "Blood glucose fluctuation ": 49.34411776392753, "Blood glucose increased ": 32.632497950668935, "Blood ketone body ": 49.52114955389936, "Blood ketone body increased ": 12.435394888071787, "Blood ketone body present ": 33.404584010333835, "Caesarean section ": 2.5725167096039185, "Cardiac operation ": 8.343784117306644, "Cataract ": 7.6274511904606035, "Cataract operation ": 11.119449694123473, "Cerebrovascular accident ": 3.930474651540381, "Coronary arterial stent insertion ": 6.089964122745548, "Coronary artery bypass ": 2.6046800893845363, "Coronary artery occlusion ": 3.332643557418689, "Dementia ": 3.502844074267552, "Dementia Alzheimer's type ": 7.023380447787936, "Dermatitis allergic ": 2.033118901061256, "Device breakage ": 38.12530261797387, "Device defective ": 8.905525675249285, "Device delivery system issue ": 11.086550692073589, "Device failure ": 57.062834096024055, "Device information output issue ": 61.78094890984487, "Device issue ": 17.539454442666727, "Device leakage ": 9.967770233278, "Device malfunction ": 30.10624552781451, "Device mechanical issue ": 19.43946140360441, "Device occlusion ": 7.443442486982543, "Diabetes mellitus inadequate control ": 28.45367603973401, "Diabetic coma ": 23.696570480335687, "Diabetic complication ": 15.972291042383242, "Diabetic foot ": 20.344386665350797, "Diabetic hyperglycaemic coma ": 30.04175447263743, "Diabetic ketoacidosis ": 18.388140824666596, "Diabetic ketosis ": 18.22546555655237, "Diabetic metabolic decompensation ": 21.728037728530648, "Diabetic nephropathy ": 8.541939893518224, "Diabetic neuropathy ": 12.64338406508318, "Diabetic retinopathy ": 22.545218006903, "Dialysis ": 12.867675214138, "Disability ": 9.672015123887183, "Expired product administered ": 4.756628150636741, "Exposure during pregnancy ": 9.110907759417248, "Exposure via breast milk ": 3.895024508278608, "Extra dose administered ": 3.581489010946356, "Eye haemorrhage ": 3.070288391555473, "Eye operation ": 5.94635035443528, "Fall ": 2.108519059731171, "Foetal death ": 3.147920386783332, "Foetal distress syndrome ": 7.333661966332029, "Foetal exposure during pregnancy ": 8.898565197663387, "Foetal growth restriction ": 2.078601464502144, "Foetal macrosomia ": 41.43538494344274, "Gangrene ": 5.532445247267643, "Gastric dilatation ": 13.06417487450303, "Gestational hypertension ": 10.42982170893441, "Glaucoma ": 3.941069370397288, "Glycosylated haemoglobin abnormal ": 18.28899499981921, "Glycosylated haemoglobin decreased ": 16.062942918259004, "Glycosylated haemoglobin increased ": 18.864414336949903, "Hepatic cirrhosis ": 2.489053552219734, "Hip fracture ": 2.323481040538985, "Hospitalisation ": 3.679227575066503, "Hyperglycaemia ": 11.34060881009752, "Hyperglycaemic unconsciousness ": 88.43868834814944, "Hyperinsulinaemic hypoglycaemia ": 13.556973157449654, "Hypoglycaemia ": 23.534065387498018, "Hypoglycaemia neonatal ": 34.73321346683186, "Hypoglycaemia unawareness ": 35.38645981053781, "Hypoglycaemic coma ": 28.799798076918613, "Hypoglycaemic encephalopathy ": 20.251674391830758, "Hypoglycaemic seizure ": 42.525194626210286, "Hypoglycaemic unconsciousness ": 66.29622330524269, "Incorrect dose administered ": 2.441650830376014, "Incorrect dose administered by device ": 46.90545637174282, "Injection site atrophy ": 93.30764804742874, "Injection site bruising ": 9.22956943458334, "Injection site discolouration ": 8.485966240901787, "Injection site erythema ": 4.857376712430522, "Injection site extravasation ": 4.395854657437314, "Injection site haemorrhage ": 3.2031583462315405, "Injection site hypersensitivity ": 44.45499172669084, "Injection site hypertrophy ": 48.60182647065912, "Injection site induration ": 11.30649294693091, "Injection site mass ": 23.58107779973397, "Injection site nodule ": 12.987068176609336, "Injection site oedema ": 4.433314725857291, "Injection site pruritus ": 8.740300564584297, "Injection site rash ": 10.97844969449756, "Injection site reaction ": 4.114331596347724, "Injection site swelling ": 2.0640411473575746, "Injection site urticaria ": 27.167168800624683, "Insulin resistance ": 14.961892558651355, "Intentional dose omission ": 6.966707818988658, "Intervertebral disc protrusion ": 2.1369276490123568, "Jaundice neonatal ": 41.368028329314974, "Ketoacidosis ": 6.9490218930578544, "Knee operation ": 5.214745948474147, "Leg amputation ": 17.19800812639043, "Lipoatrophy ": 21.88253394069027, "Lipodystrophy acquired ": 10.242424622805435, "Lipohypertrophy ": 22.755453490831044, "Liquid product physical issue ": 9.255694770450212, "Localised infection ": 7.943715523025998, "Low birth weight baby ": 3.629158159883025, "Lower limb fracture ": 3.144520046999083, "Macular degeneration ": 4.952040199595427, "Maternal exposure during pregnancy ": 6.406750246669916, "Myocardial infarction ": 2.7526349727555184, "Needle issue ": 2.6686461125603103, "Neonatal respiratory distress syndrome ": 6.966338753399174, "Neoplasm malignant ": 2.4395184968672896, "Osteomyelitis ": 2.376699498403231, "Pancreatic carcinoma ": 2.6328489590195447, "Parkinson's disease ": 2.080299468795502, "Post procedural haemorrhage ": 2.0661060150427715, "Pre-eclampsia ": 19.20793612579897, "Pregnancy ": 3.3106054400373, "Premature baby ": 12.03020437085858, "Premature delivery ": 9.660720204820374, "Premature labour ": 3.151873147420036, "Product administration error ": 2.470478097143442, "Product communication issue ": 20.14782096978226, "Product container issue ": 17.11373965462868, "Product dispensing error ": 4.630873659602108, "Product leakage ": 7.794624856468626, "Product physical issue ": 10.355565363942771, "Product quality issue ": 10.178689697245726, "Product storage error ": 11.31339515297005, "Product use complaint ": 5.06773272916548, "Renal disorder ": 2.3261728046523658, "Renal transplant ": 7.9629372065228194, "Respiratory disorder neonatal ": 29.521348740205312, "Retinopathy ": 5.4030603618121535, "Road traffic accident ": 3.0535359425482933, "Shock hypoglycaemic ": 11.670328721241091, "Skin reaction ": 3.3825724115326827, "Skin ulcer ": 3.069922889751004, "Sopor ": 2.267081193228252, "Spinal operation ": 2.087569562098111, "Spinal stenosis ": 3.1765705964814805, "Staphylococcal infection ": 2.172171688203573, "Stent placement ": 2.9597525650870518, "Stillbirth ": 4.949026992548856, "Surgery ": 3.09334220537124, "Toe amputation ": 19.544256783098888, "Treatment noncompliance ": 3.863995959109338, "Ventricular septal defect ": 4.34426985822138, "Weight increased ": 2.068116296010535, "Wheelchair user ": 5.280469474473868, "Wrong product administered ": 19.17303623246681, "Wrong technique in product usage process ": 2.536656019225945}
\ No newline at end of file
+{"Abdominal discomfort": 2.476824760221382, "Acne": 3.6671192528914376, "Acute lung injury": 121.32072006077128, "Adverse drug reaction": 2.200835674183809, "Ankle fracture": 4.636964475853394, "Arthritis": 5.491057816260588, "Arthropathy": 2.8960090160883434, "Blood cholesterol increased": 2.112261464991856, "Blood pressure abnormal": 2.256924166313785, "Blood pressure diastolic abnormal": 22.25841646075108, "Blood pressure systolic increased": 4.1449850539173525, "Bone erosion": 10.493307234500763, "C-reactive protein increased": 7.839614768416433, "Cellulitis": 2.678123215448173, "Clostridium difficile infection": 5.54246275248921, "Condition aggravated": 2.156673675015374, "Crepitations": 17.44135697799511, "Cytopenia": 4.372063398814213, "Deformity": 9.367281977018592, "Device fastener issue": 1471.0029315398006, "Diverticulitis": 14.434827699008416, "Drug hypersensitivity": 3.043320830293036, "Drug ineffective": 4.229863780779129, "Drug intolerance": 15.035481451488492, "Drug-induced liver injury": 5.111602713478518, "Dry eye": 4.938555708644908, "Dyspepsia": 4.05552104274509, "Dysstasia": 2.710459972720797, "Exostosis": 31.017502864808364, "Fibromyalgia": 2.7804507521602626, "Foot deformity": 13.959623179902268, "Foot fracture": 2.9140784471922734, "Frustration tolerance decreased": 16.509879225402386, "Gastrointestinal disorder": 5.063125744734635, "General physical health deterioration": 2.862504016883816, "General symptom": 35.438560814111035, "Gingival abscess": 172.0566540200923, "Gingival disorder": 31.36864171977029, "Grip strength decreased": 8.326785607525586, "Hand deformity": 6.879551589895835, "Heart rate decreased": 2.0844129315542586, "Hepatic enzyme increased": 4.733180886479726, "Hepatitis": 3.163068927684692, "Ill-defined disorder": 2.49793075857242, "Immunodeficiency": 9.092082399457526, "Impaired healing": 2.7718243471613344, "Inflammation": 3.3006011702371225, "Joint dislocation": 9.479033920455276, "Joint effusion": 11.502311676159648, "Joint range of motion decreased": 4.955482568297077, "Joint space narrowing": 153.61749085687117, "Joint stiffness": 2.8378466994677085, "Joint swelling": 10.51286687981236, "Juvenile idiopathic arthritis": 17.801224108714596, "Laryngitis": 12.469178823336575, "Leukopenia": 2.053650653473096, "Lower respiratory tract infection": 2.121232657992403, "Lymphocyte count decreased": 3.418120765434603, "Mucous stools": 20.977263298524772, "Musculoskeletal chest pain": 4.719948239524133, "Musculoskeletal pain": 2.3515488676030785, "Musculoskeletal stiffness": 7.049632272713711, "Mycobacterium tuberculosis complex test positive": 74.4786979780844, "Nasopharyngitis": 2.3936669600295573, "Neuropathy peripheral": 2.0405863794266565, "Nodule": 4.690373760535444, "Normocytic anaemia": 13.653590527731671, "Osteoarthritis": 7.806537734127797, "Osteosclerosis": 42.97338569283722, "Pancytopenia": 2.050659522914112, "Peripheral swelling": 2.8859245101449, "Pharyngeal swelling": 2.420809110390329, "Pigmentation disorder": 11.873463724173384, "Pneumonitis": 2.2873135855192306, "Polyarthritis": 8.21102447278744, "Polyneuropathy": 2.535098900975438, "Psoriasis": 3.5272663669278144, "Psoriatic arthropathy": 13.357063417006774, "Pulmonary fibrosis": 2.838213403350176, "Pulmonary toxicity": 5.852073812441962, "Raynaud's phenomenon": 6.070559598029222, "Red blood cell sedimentation rate increased": 12.453092877441405, "Rheumatoid arthritis": 13.246104118282505, "Rheumatoid nodule": 22.908391574775177, "Seronegative arthritis": 41.2441813039429, "Sinusitis": 3.118823930010845, "Sjogren's syndrome": 11.636508659396393, "Skin lesion": 2.312087001880263, "Skin plaque": 12.352113658068822, "Skin ulcer": 2.8791796685356794, "Suspected suicide": 5.301131889670181, "Synovial cyst": 12.24612879296354, "Synovitis": 14.29554955806094, "Tendon disorder": 10.046108271160474, "Tendonitis": 3.6759919871292, "Tenosynovitis": 24.482345810506185, "Therapeutic product effect decreased": 2.0385937466456334, "Therapeutic product effect incomplete": 2.761804072674276, "Therapeutic response decreased": 7.3718907462375824, "Transaminases increased": 2.0377371490698657, "Treatment failure": 3.370164976383998, "Tuberculosis": 6.586947556867925, "Upper respiratory tract infection": 6.507890063247188, "White blood cell count abnormal": 8.763794364786644, "White blood cell count decreased": 2.099842969963703, "Wound": 2.1826768333815227}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/657.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/657.json
index 39b5844e64d..da3658e144e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/657.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/657.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 6.499697901118006, "Abortion induced ": 3.8912446113691455, "Abortion spontaneous ": 4.061530013123205, "Acidosis hyperchloraemic ": 440.4716700362024, "Acute generalised exanthematous pustulosis ": 2.915635530766832, "Acute hepatic failure ": 4.581103047247436, "Acute psychosis ": 12.312738919978113, "Adverse drug reaction ": 2.524222450790091, "Affect lability ": 5.242873019592547, "Affective disorder ": 7.737605801786861, "Aggression ": 12.187562621272214, "Agitation ": 3.474589138694722, "Altered state of consciousness ": 2.281512622524628, "Ammonia increased ": 7.289186730475309, "Anger ": 5.159217232548572, "Anticonvulsant drug level above therapeutic ": 30.799991497847827, "Anticonvulsant drug level below therapeutic ": 33.849691263280874, "Anticonvulsant drug level decreased ": 21.300144797851804, "Anticonvulsant drug level increased ": 12.941280590671036, "Anxiety disorder ": 3.872946813867824, "Apathy ": 3.215824000145393, "Apnoea ": 3.6717342005658433, "Apnoeic attack ": 14.029602172204472, "Aspiration ": 2.954466996728858, "Asterixis ": 20.13979989690805, "Ataxia ": 12.452946068832151, "Atonic seizures ": 45.35319020774524, "Atrial septal defect ": 3.719095114159988, "Atrioventricular block first degree ": 2.115235232549741, "Atrioventricular block second degree ": 2.207083209496211, "Atrophy ": 7.871720056272367, "Attention deficit hyperactivity disorder ": 5.210961635223912, "Aura ": 16.286123382144673, "Autism spectrum disorder ": 2.5115092688028566, "Autonomic nervous system imbalance ": 2.060579054294554, "Behaviour disorder ": 24.082626939401504, "Blood chloride increased ": 104.64334134233098, "Blood pH decreased ": 92.12923947398713, "Bradyarrhythmia ": 4.518278149119372, "Bradycardia foetal ": 4.348513057783526, "Bradyphrenia ": 3.5875613242267845, "Bradypnoea ": 2.3146938810641284, "Bronchiolitis ": 2.2402039333998998, "Cachexia ": 4.305684461103573, "Caesarean section ": 2.828039017847453, "Cardiopulmonary failure ": 3.732807184881615, "Cerebral atrophy ": 4.044566570875708, "Cerebral disorder ": 2.050262731303567, "Change in seizure presentation ": 33.00445893528884, "Cholestatic liver injury ": 5.056525154829041, "Cleft palate ": 3.658521851593559, "Clonic convulsion ": 20.53755957175016, "Clonus ": 2.4512112549588068, "Cognitive disorder ": 5.90983230436221, "Completed suicide ": 2.8115928000046866, "Condition aggravated ": 2.5681435723474646, "Congenital anomaly ": 4.2729897688882055, "Conjunctival hyperaemia ": 2.1527398136336577, "Coordination abnormal ": 3.885656072407611, "Culture urine positive ": 20.55012709141713, "Delirium ": 2.2967244584468376, "Delusion ": 7.289089776186576, "Depressed mood ": 2.294681625794916, "Depression ": 2.1160099814550777, "Depressive symptom ": 2.2593546973045444, "Dermatitis allergic ": 2.295182024544755, "Developmental delay ": 5.288146215482204, "Developmental hip dysplasia ": 17.14280969596731, "Diabetic neuropathy ": 4.293904056210915, "Disease recurrence ": 2.780853434363451, "Drooling ": 3.07628284858598, "Drop attacks ": 15.394828611129451, "Drug effective for unapproved indication ": 2.6453370919791683, "Drug eruption ": 2.147818082036029, "Drug ineffective ": 5.939343527639412, "Drug ineffective for unapproved indication ": 8.978242273934653, "Drug interaction ": 3.046341243010516, "Drug level below therapeutic ": 4.758191441114706, "Drug level decreased ": 7.498197467674996, "Drug level increased ": 2.8144704735512738, "Drug reaction with eosinophilia and systemic symptoms ": 13.917262267872736, "Drug resistance ": 15.653016394293587, "Drug withdrawal convulsions ": 8.602827307342709, "Dyskinesia ": 2.775534225488941, "Dysmorphism ": 6.939375777940857, "Electroencephalogram abnormal ": 20.781853516182707, "Electrolyte imbalance ": 2.140458865779392, "Emotional disorder ": 2.2513120162268887, "Encephalitis autoimmune ": 16.196939528440094, "Encephalopathy ": 3.5538455699192246, "Eosinophilia ": 3.857571960361709, "Eosinophilic cystitis ": 128.51419354834565, "Epilepsia partialis continua ": 65.6393091691687, "Epilepsy ": 16.666419495506936, "Epileptic encephalopathy ": 111.82760703308053, "Euphoric mood ": 2.157143875984096, "Excessive eye blinking ": 12.077227753748533, "Exposure during pregnancy ": 2.7279511649259867, "Feeling of despair ": 2.139695809851041, "Focal dyscognitive seizures ": 50.58469381913426, "Foetal distress syndrome ": 3.0915571262775283, "Foetal exposure during pregnancy ": 5.635095960703141, "Foetal growth restriction ": 2.788827944786607, "Foetal malformation ": 18.912685862336, "Gastrointestinal hypomotility ": 14.053173956490076, "Generalised tonic-clonic seizure ": 17.398498038491827, "Gingival hypertrophy ": 8.952639175588828, "Haemangioma ": 7.876656868223224, "Haemodynamic instability ": 5.880561818582035, "Haemophagocytic lymphohistiocytosis ": 3.036925348731608, "Hallucination, auditory ": 2.837230167116293, "Hallucination, visual ": 3.391483978688039, "Hallucinations, mixed ": 7.0931842792459125, "Hostility ": 7.656645987949806, "Hydrocephalus ": 3.035015014493942, "Hyperammonaemia ": 9.003340065181149, "Hyperammonaemic encephalopathy ": 14.164951703507915, "Hypercapnia ": 3.568336968158876, "Hypernatraemia ": 3.493030303050896, "Hyperreflexia ": 3.1893209471104256, "Hypersexuality ": 5.959144632861045, "Hypertransaminasaemia ": 3.644663696860511, "Hypertrophic cardiomyopathy ": 22.06533167375348, "Hypoglycaemia neonatal ": 4.509074734901488, "Hypomagnesaemia ": 7.557550461647026, "Hyponatraemia ": 2.491222663930421, "Hyporeflexia ": 2.5758231206481925, "Hypotonia ": 3.652039108564368, "Hypotonia neonatal ": 12.020981570990903, "Impulsive behaviour ": 10.038878560968842, "Inappropriate antidiuretic hormone secretion ": 2.180918036870101, "Incorrect route of product administration ": 2.565387640515437, "Increased bronchial secretion ": 3.764786053933884, "Infantile spasms ": 45.33390919673814, "Intellectual disability ": 15.112956368947549, "Intestinal ischaemia ": 2.0691279262923548, "Intestinal perforation ": 3.904256428394869, "Intra-abdominal pressure increased ": 228.95562461413263, "Iodine allergy ": 22.82760212343091, "Irritability ": 7.3781793056509715, "Language disorder ": 5.664683744393851, "Left ventricular hypertrophy ": 2.6927629518092417, "Leukocytosis ": 2.018622219861783, "Low birth weight baby ": 5.970938335265829, "Major depression ": 4.97187036849143, "Malabsorption ": 2.7857197542984866, "Mania ": 2.0401322781360087, "Mastication disorder ": 4.160746158167752, "Maternal exposure before pregnancy ": 8.056050921382376, "Maternal exposure during pregnancy ": 4.624810248682817, "Memory impairment ": 2.415526318538046, "Mental disorder ": 2.439086821822709, "Mental status changes ": 4.058162025087208, "Metabolic acidosis ": 2.5634366948375056, "Metabolic encephalopathy ": 6.244520019860818, "Mitochondrial DNA mutation ": 48.901741466100425, "Mood altered ": 5.388692778598893, "Mood swings ": 3.505062928250133, "Motor dysfunction ": 3.2781991690739973, "Multiple organ dysfunction syndrome ": 2.963596066497437, "Multiple-drug resistance ": 108.75641881042888, "Muscle twitching ": 2.412541363672651, "Myoclonic epilepsy ": 62.927670597876926, "Myoclonus ": 10.287496522898865, "Necrosis ischaemic ": 50.15914745594712, "Neonatal respiratory depression ": 19.13978505224685, "Neonatal respiratory distress syndrome ": 3.9778226864152417, "Neurological decompensation ": 9.669998720543736, "Neuromyopathy ": 19.54209077248775, "Neuropsychological symptoms ": 7.691601974956101, "Nystagmus ": 3.8141550270278377, "Off label use ": 2.4563261180709497, "Oliguria ": 2.231500098946488, "Overdose ": 2.2436122680641586, "Paradoxical drug reaction ": 6.250227453284563, "Paranoia ": 3.360779403643656, "Paraplegia ": 6.776141061300896, "Partial seizures ": 46.1992944010548, "Partial seizures with secondary generalisation ": 37.36526787412522, "Patent ductus arteriosus ": 2.964952658625009, "Persecutory delusion ": 2.4905237008043377, "Personality change ": 4.953128146583439, "Personality disorder ": 5.675585405055448, "Petit mal epilepsy ": 22.29898042537243, "Pneumatosis ": 36.04375776367828, "Pneumonia aspiration ": 2.9072903038495497, "Polydactyly ": 8.229104630163784, "Postictal paralysis ": 31.91848511431913, "Postictal psychosis ": 272.89342297561643, "Posture abnormal ": 2.933612361429914, "Potentiating drug interaction ": 4.641629947325373, "Pregnancy ": 8.080025611062089, "Premature baby ": 2.3094888250466084, "Premature delivery ": 3.328003682593172, "Product administered to patient of inappropriate age ": 3.3369634952941434, "Product residue present ": 2.533058174618461, "Product substitution issue ": 9.064376919790805, "Product use issue ": 2.4612933664617938, "Propofol infusion syndrome ": 12.247010364483812, "Psychiatric symptom ": 7.15761083068843, "Psychogenic seizure ": 19.69329021393718, "Psychomotor hyperactivity ": 5.535546376860114, "Psychomotor retardation ": 2.175933810464027, "Psychomotor skills impaired ": 2.5014008895168494, "Psychotic disorder ": 6.390337489606312, "Rash maculo-papular ": 3.2324385088878818, "Renal fusion anomaly ": 59.24527710191733, "Renal tubular acidosis ": 6.02518641997147, "Respiratory failure ": 2.2974419437958447, "Rhabdomyolysis ": 3.298785042958482, "Sedation ": 6.220428126001628, "Sedation complication ": 2.1573489769450336, "Seizure ": 14.79287427356818, "Seizure cluster ": 73.28533167714178, "Selective eating disorder ": 4.855196571912353, "Self-destructive behaviour ": 4.109508004727169, "Serum ferritin increased ": 2.4478264342617595, "Sinus arrest ": 3.0138993808810834, "Skin erosion ": 2.03787929668052, "Small for dates baby ": 8.806245491809387, "Social avoidant behaviour ": 2.878733973638248, "Somnolence ": 2.714435136409663, "Sopor ": 2.609389755601128, "Spina bifida ": 8.011296812519875, "Staring ": 4.781824550238014, "Status epilepticus ": 60.64410459081636, "Stevens-Johnson syndrome ": 3.699917652129902, "Stillbirth ": 5.663763222584945, "Stupor ": 2.8858574826976136, "Substance-induced psychotic disorder ": 23.825084299295536, "Sudden unexplained death in epilepsy ": 94.57816240155756, "Suicidal behaviour ": 5.902091469188544, "Suicidal ideation ": 2.750252117852118, "Supraventricular tachycardia ": 2.713556338607779, "Suspected suicide ": 8.528941382301895, "Systemic inflammatory response syndrome ": 8.421576799876128, "Talipes ": 5.463303368911634, "Temporal lobe epilepsy ": 15.916514601487258, "Teratogenicity ": 34.61988502289864, "Therapeutic product effect incomplete ": 3.3942691420320785, "Therapeutic response changed ": 10.204610223234935, "Therapeutic response decreased ": 2.496085329388006, "Therapy cessation ": 2.247097765317061, "Therapy non-responder ": 3.371514786742034, "Thinking abnormal ": 3.386492143518465, "Tongue disorder ": 2.2281372618864235, "Tonic convulsion ": 33.059397324019265, "Toxic encephalopathy ": 3.5640887841101803, "Toxic epidermal necrolysis ": 6.027602506804378, "Toxicity to various agents ": 2.8515691580952884, "Treatment failure ": 2.6931910484583472, "Treatment noncompliance ": 2.425354681140929, "Tubulointerstitial nephritis ": 4.359245735523142, "Unresponsive to stimuli ": 2.125079441636542, "Ventricular septal defect ": 6.312468236404844, "Weight fluctuation ": 2.1132996425311807, "Wrong patient received product ": 2.218197256067405}
\ No newline at end of file
+{"Acute respiratory distress syndrome": 2.1480643623008238, "Alopecia areata": 10.659458968636216, "Anti-thyroid antibody": 139.0561226804252, "Anti-thyroid antibody positive": 314.2635925217569, "Ataxia": 2.8206254294326585, "Autoimmune disorder": 2.3888378570371747, "Autoimmune haemolytic anaemia": 18.532482943166645, "Autoimmune hepatitis": 7.080337086155354, "Autoimmune hypothyroidism": 50.504121548127145, "Autoimmune thyroid disorder": 128.63954253890964, "Autoimmune thyroiditis": 53.81539885501928, "Bladder disorder": 3.2872257989616585, "Blood lactate dehydrogenase increased": 2.383071106755942, "Blood thyroid stimulating hormone abnormal": 120.0199448828688, "Blood thyroid stimulating hormone decreased": 82.55506716577959, "Blood thyroid stimulating hormone increased": 21.867074426987816, "Blood urine present": 3.8270475160173096, "Bradycardia": 7.20856554138219, "C-reactive protein increased": 5.295141981832133, "CD4 lymphocytes decreased": 16.79773245758836, "Central nervous system lesion": 17.332577848127862, "Cervical dysplasia": 11.28306537349636, "Cholecystitis": 5.911342662459463, "Cholecystitis acute": 11.903582654343415, "Contusion": 2.2729604260654117, "Diplopia": 2.382423991014396, "Drug exposure before pregnancy": 93.81755849920506, "Drug monitoring procedure not performed": 46.9529179390628, "Endocrine ophthalmopathy": 63.31984974641683, "Expanded disability status scale score increased": 95.1796241988632, "Flushing": 2.731590079227954, "Gait disturbance": 2.2485655259296804, "Gingival bleeding": 3.652575526297622, "Goitre": 8.872073549853997, "Goodpasture's syndrome": 162.12141247352884, "Graves' disease": 126.52278402127328, "Haematocrit decreased": 5.630765438191701, "Haemoglobin decreased": 2.18752411265188, "Haemolytic anaemia": 5.45656695782342, "Haemophagocytic lymphohistiocytosis": 2.4597961614117203, "Haemoptysis": 2.801905368612896, "Heart rate abnormal": 3.131755703715311, "Heart rate decreased": 3.255732245459075, "Heart rate increased": 2.161256890441129, "Heart rate irregular": 2.8213180159611917, "Hemiparesis": 3.021339659561258, "Hyperthermia": 3.88099883898254, "Hyperthyroidism": 30.2312216890142, "Hypothyroidism": 8.924267166383311, "Immune thrombocytopenia": 44.37947752822445, "Immunosuppression": 4.518276277774243, "Incorrect drug administration rate": 24.455131226712517, "Incorrect product administration duration": 4.581712432490049, "Increased appetite": 2.0809520463656384, "Laboratory test abnormal": 3.6206094072122887, "Leukopenia": 2.3317419786591964, "Listeria sepsis": 131.0666947238926, "Listeriosis": 79.27967180364159, "Liver function test increased": 2.0601934002263538, "Lymphocyte count abnormal": 158.72825340749168, "Lymphocyte count decreased": 33.562836826355564, "Lymphocyte percentage decreased": 99.31376832212716, "Lymphopenia": 28.234542375342723, "Magnetic resonance imaging abnormal": 87.61157057206633, "Malignant melanoma": 2.076460599897214, "Mean cell haemoglobin decreased": 27.14992852047455, "Mean cell volume decreased": 16.241345340506424, "Mean cell volume increased": 11.547690398123596, "Meningitis listeria": 143.58795662770856, "Monocyte count decreased": 38.04014477140793, "Monocyte percentage decreased": 200.0395778631197, "Mood altered": 2.371432110116705, "Motor dysfunction": 2.3003001074795377, "Multiple sclerosis": 17.252470565206767, "Multiple sclerosis relapse": 56.59241725987772, "Muscle spasticity": 5.676457634945312, "Muscular weakness": 2.1318373436145923, "Neutrophil count abnormal": 21.74439468860889, "Neutrophil count increased": 10.012259346130207, "Neutrophil percentage increased": 60.83023492600508, "Optic neuritis": 5.321645901199993, "Paraparesis": 11.09274194969022, "Petechiae": 6.095128185955944, "Platelet count abnormal": 17.110926383647836, "Platelet count decreased": 4.015641322710808, "Pneumonitis": 3.7566032571996937, "Pregnancy": 3.201617886173453, "Procalcitonin increased": 18.293932959292068, "Progressive multifocal leukoencephalopathy": 6.964882080595932, "Protein urine present": 8.542987368196941, "Proteinuria": 2.2707625252706496, "Pulmonary alveolar haemorrhage": 4.6561172992204565, "Quadriplegia": 7.707385639263836, "Rash": 3.180316469882347, "Rash pruritic": 3.208048352210734, "Red blood cell count decreased": 3.3692793669814365, "Red blood cells urine positive": 46.658476293052544, "Red cell distribution width increased": 9.215695086589596, "Sinus bradycardia": 6.043849779524629, "Splenomegaly": 2.0481813709134262, "T-lymphocyte count decreased": 50.21609759431973, "Temperature intolerance": 14.921472685548324, "Thrombocytopenia": 2.096089436908775, "Thrombotic thrombocytopenic purpura": 4.93767380130779, "Thyroid cancer": 4.484581217835413, "Thyroid disorder": 16.254940210782458, "Thyroid function test abnormal": 21.81544765764171, "Thyroid hormones increased": 23.092107926950558, "Thyroid mass": 5.482863979626599, "Thyroid stimulating immunoglobulin": 1033.8778732406265, "Thyroidectomy": 20.328285574759636, "Thyroiditis": 16.647929482522013, "Thyroiditis subacute": 12.849524972374889, "Thyroxine decreased": 55.69847189331709, "Thyroxine free abnormal": 302.4273125490369, "Thyroxine free decreased": 57.141289884912666, "Thyroxine free increased": 63.975257517751785, "Thyroxine increased": 71.30359012543038, "Tri-iodothyronine free increased": 105.44913636537528, "Tri-iodothyronine increased": 79.8700407430169, "Tuberculosis": 2.017288046519175, "Type 1 diabetes mellitus": 2.6795799123452078, "Unevaluable event": 3.508597538857829, "Urinary sediment present": 56.49172142686853, "Urinary tract infection": 3.333870678170529, "Vitiligo": 11.135971197267155, "White blood cell count abnormal": 9.315344542863883, "White blood cell count increased": 3.957638676110964, "White blood cells urine positive": 25.172437837227594}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/658.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/658.json
index 28be03de92d..e747a6afe81 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/658.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/658.json
@@ -1 +1 @@
-{"Malignant melanoma ": 100.69410941559936, "Malignant melanoma in situ ": 326.721474720663, "Vision blurred ": 8.44443590716779}
\ No newline at end of file
+{"Acute kidney injury": 2.1891350923761848, "Blood lactate dehydrogenase increased": 8.227162702034047, "Cytokine release syndrome": 7.951307032179892, "Cytopenia": 13.417129943178928, "Diffuse large B-cell lymphoma": 28.23179277829084, "Disease progression": 17.094340585731032, "Febrile neutropenia": 12.158280467940354, "Follicular lymphoma": 144.66772577773915, "Infection": 3.162852807562958, "Intentional product use issue": 2.9233350487069534, "Malignant neoplasm progression": 3.2455337659196712, "Myelodysplastic syndrome": 13.012377022695713, "Myelosuppression": 10.110656034257596, "Neoplasm progression": 4.269274301021267, "Neuropathy peripheral": 2.537568971464209, "Neutropenia": 8.111450693881812, "Neutrophil count abnormal": 81.81827629756864, "Neutrophil count decreased": 6.000005831187788, "Off label use": 6.332435332578341, "Plasma cell myeloma": 14.985335608817405, "Platelet count abnormal": 51.18205160575494, "Platelet count decreased": 5.541648036680367, "Platelet disorder": 159.68681439580797, "Pneumonia": 4.158702585723541, "Rash maculo-papular": 3.286795052403451, "Rash pruritic": 2.6354100886708545, "Renal impairment": 2.3199108905547607, "Thrombocytopenia": 4.246335089898712, "White blood cell count decreased": 5.4684705617063205}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/659.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/659.json
index 1e0e5a7ff58..f79e58bd6d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/659.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/659.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 3.506483117110069, "Accidental overdose ": 2.822563514884808, "Aggression ": 2.058743224429961, "Agitation ": 3.450032634703039, "Akinesia ": 72.04836978935596, "Anxiety ": 2.382816806697764, "Apathy ": 14.09673920175693, "Balance disorder ": 2.636679247003219, "Behaviour disorder ": 5.929558998271033, "Blood creatine phosphokinase increased ": 2.4012481087550515, "Bradykinesia ": 35.247123554883295, "Cognitive disorder ": 4.37768256367095, "Completed suicide ": 2.3224432487173647, "Compulsive shopping ": 252.64324083253203, "Condition aggravated ": 2.567978954563276, "Delirium ": 4.631684178419766, "Delusion ": 19.5775776476232, "Dementia ": 3.374356363861173, "Depressed mood ": 2.7511959485787765, "Depression ": 2.9537147464829743, "Dopamine dysregulation syndrome ": 2264.228123339601, "Drug abuse ": 3.159321513760441, "Drug dependence ": 3.5291502802900347, "Drug interaction ": 3.804613730635983, "Drug withdrawal syndrome ": 4.847073654679399, "Dysarthria ": 2.453991309162341, "Dyskinesia ": 56.28044208587159, "Dysphagia ": 2.202798262390475, "Dysphoria ": 9.14877389115202, "Dystonia ": 14.121036460241662, "Eating disorder ": 5.543899076624224, "Encephalopathy ": 3.995185386549276, "Extrapyramidal disorder ": 4.9289084823178575, "Fall ": 2.463238903863617, "Gait disturbance ": 3.2517731590100625, "Gambling disorder ": 254.79365735789688, "Hallucination ": 10.923715051688882, "Hallucination, auditory ": 11.089738228310518, "Hallucination, tactile ": 659.9624101125918, "Hallucination, visual ": 34.39880764038122, "Hypersexuality ": 259.0407640781477, "Hypokinesia ": 5.186140096993126, "Hypomania ": 19.62073852543799, "Hypotension ": 2.22136409761452, "Hypothermia ": 8.659507732707416, "Impulse-control disorder ": 257.6020699368528, "Intentional overdose ": 2.1956543299060334, "Intentional product misuse ": 4.184631161899871, "Irritability ": 3.0533610105981435, "Jealous delusion ": 617.832767470861, "Labelled drug-disease interaction issue ": 1272.462204249185, "Mood altered ": 4.0301309454851015, "Motor dysfunction ": 10.732357297884976, "Movement disorder ": 7.844531657826774, "Muscle rigidity ": 16.405095550951703, "Myoclonus ": 10.331335123572996, "Neuroleptic malignant syndrome ": 17.41257569686684, "Obsessive-compulsive disorder ": 14.00328034366333, "On and off phenomenon ": 850.806344389586, "Oromandibular dystonia ": 128.2575176357359, "Orthostatic hypotension ": 8.590013370322712, "Overdose ": 2.327211917401294, "Paranoia ": 12.369932604489309, "Paraphilia ": 980.963496440671, "Parkinson's disease ": 47.02115758391009, "Parkinsonian gait ": 161.27818397582072, "Parkinsonism ": 38.09030227816618, "Product administration error ": 2.644137164702144, "Psychotic disorder ": 10.037793525066412, "Restlessness ": 3.786902530408209, "Somnolence ": 2.4987852500368537, "Speech disorder ": 4.789574844356002, "Stereotypy ": 185.73751418975763, "Therapeutic response shortened ": 176.43122478116686, "Tremor ": 2.4738617204574243, "Withdrawal syndrome ": 4.537739524851074}
\ No newline at end of file
+{"Decreased appetite": 2.5915455189610968, "Hypertension": 4.255313693547228, "Malignant neoplasm progression": 10.076448626612216, "Palmar-plantar erythrodysaesthesia syndrome": 21.372306069844967, "Product use in unapproved indication": 4.717998904059279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/66.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/66.json
index 2f5ffb3a4a0..01aadd4cb4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/66.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/66.json
@@ -1 +1 @@
-{"Abdominal pain ": 4.005379349207265, "Anaphylactic reaction ": 14.08493008854426, "Ankylosing spondylitis ": 86.78172966017884, "Asthenia ": 2.602966987063198, "Crohn's disease ": 25.94744480358513, "Diarrhoea ": 2.184398709408377, "Drug ineffective ": 4.702831812860649, "Drug intolerance ": 12.137867889216734, "Dry eye ": 95.73546858846136, "General symptom ": 717.8213894303317, "Inflammation ": 22.37178063566425, "Lacrimation increased ": 90.57457375383964, "Loss of personal independence in daily activities ": 17.46137590846161, "Oedema ": 17.355048168592948, "Pain in extremity ": 2.3360798188649907, "Pelvic pain ": 121.14916487980284, "Plantar fasciitis ": 1020.8310174406388, "Psoriasis ": 46.48257774633006, "Synovitis ": 50.74562628472639, "Tendonitis ": 103.15099803175072, "Therapeutic product effect incomplete ": 16.622980979336923, "Therapy non-responder ": 24.78416704670003}
\ No newline at end of file
+{"Application site erythema": 527.8871000544974, "Application site exfoliation": 1032.0127431283329, "Application site haemorrhage": 428.25188660894895, "Application site oedema": 406.4519230286784, "Application site pain": 125.9977490592772, "Application site pruritus": 78.91465391185146, "Application site pustules": 1764.2703490542085, "Application site reaction": 97.91933944061462, "Application site scab": 4146.579006978819, "Application site swelling": 252.3272667956982, "Application site vesicles": 160.43156103925915, "Erythema": 3.1465171512188377, "Off label use": 10.960985886143494, "Pain": 2.4007053848577207, "Skin reaction": 85.10522020518985, "Skin tightness": 91.43288120731528}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/660.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/660.json
index 696a311129b..45f895e74c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/660.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/660.json
@@ -1 +1 @@
-{"Acute generalised exanthematous pustulosis ": 3.1864692528153307, "Acute myelomonocytic leukaemia ": 19.9330575042766, "Acute psychosis ": 4.078748428537944, "Acute respiratory distress syndrome ": 2.114842279257867, "Alanine aminotransferase abnormal ": 2.2072020919878814, "Alanine aminotransferase increased ": 2.170821670450734, "Anaphylactic shock ": 2.86058351795023, "Anaphylactoid reaction ": 4.339935132695832, "Anion gap increased ": 6.3262374118929445, "Anterior chamber cell ": 4.331710579190829, "Anterior chamber flare ": 14.988135685507585, "Aspartate aminotransferase increased ": 2.251674175645048, "Aspergillus infection ": 2.240465102232472, "Autoimmune haemolytic anaemia ": 2.2586392446645185, "Azotaemia ": 2.0010674817089877, "Bacteraemia ": 3.442758052709024, "Balance disorder ": 13.24243098999399, "Blood calcium decreased ": 88.41403438728841, "Blood calcium increased ": 2.6597231874285816, "Blood lactate dehydrogenase increased ": 2.100154410227628, "Brain abscess ": 2.959564359518636, "Breath sounds abnormal ": 2.6193228652632774, "Cardiac tamponade ": 3.3419244869663847, "Clostridium colitis ": 11.969164167580772, "Clostridium difficile colitis ": 7.428796671954979, "Clostridium difficile infection ": 5.886259591739354, "Coagulation time prolonged ": 2.233926540903445, "Coagulopathy ": 3.287296278170556, "Cognitive disorder ": 24.327299973212217, "Compartment syndrome ": 2.7846165817060897, "Conjunctival hyperaemia ": 3.310148512940972, "Constipation ": 6.582306371412972, "Corneal oedema ": 4.428008563993886, "Corneal perforation ": 15.140872343756246, "Coronavirus test positive ": 7.502933792716737, "Creatinine renal clearance decreased ": 119.66811580070424, "Creatinine renal clearance increased ": 99.70604777908396, "Cross sensitivity reaction ": 5.449939383665131, "Crystal nephropathy ": 33.98188359258177, "Delirium ": 2.434575165138333, "Depressed level of consciousness ": 14.044451354883655, "Dermatitis ": 2.5236922347929607, "Dermatitis allergic ": 2.447716675410443, "Dermatitis exfoliative ": 2.669590634810534, "Disorganised speech ": 8.736299620696448, "Disseminated intravascular coagulation ": 2.343900830570764, "Disseminated tuberculosis ": 11.563651539049122, "Drug eruption ": 5.227316988337027, "Drug hypersensitivity ": 2.875681206602871, "Drug ineffective for unapproved indication ": 2.230452642797883, "Drug interaction ": 3.594661829181225, "Drug reaction with eosinophilia and systemic symptoms ": 4.455676240844641, "Drug resistance ": 5.016391771274482, "Drug-induced liver injury ": 5.521010801650552, "Dysbiosis ": 20.051264052504667, "Dysphoria ": 2.072709770882443, "Electrocardiogram QT prolonged ": 9.18930901746827, "Endophthalmitis ": 3.4991728629313754, "Eosinophil count increased ": 2.4818682441324733, "Eosinophilic pneumonia ": 4.489157053681913, "Eosinophilic pneumonia acute ": 7.28086587239545, "Epidermal necrosis ": 9.238672864122984, "Erythema multiforme ": 2.613513015709456, "Erythema nodosum ": 2.1353646994259643, "Erythema of eyelid ": 2.370244644901882, "Escherichia infection ": 3.311533091880843, "Face oedema ": 2.3360535632735577, "Fall ": 4.503090774256149, "Fibrin ": 281.83310809847814, "Fixed eruption ": 14.22100656015794, "Gastrointestinal motility disorder ": 4.399158594160427, "Granulocytopenia ": 2.5016452355849217, "Haemodynamic instability ": 4.813153597234976, "Haemorrhage urinary tract ": 2.1935999456022794, "Hallucination, visual ": 2.511103063728401, "Henoch-Schonlein purpura ": 2.1935999456022794, "Hepatic function abnormal ": 4.947155426804847, "Hepatitis acute ": 4.616759946338017, "Hepatitis toxic ": 2.9231998092304585, "Hepatocellular injury ": 2.52802188802698, "Hepatosplenomegaly ": 2.767922001183315, "Hepatotoxicity ": 2.7849205834653707, "Hyperaemia ": 7.255328752525575, "Hypersensitivity myocarditis ": 16.7442650482528, "Hypersensitivity vasculitis ": 3.4949224392947262, "Hypocoagulable state ": 7.724384290183256, "Hypomagnesaemia ": 3.0398567391453235, "Hypotension ": 4.263501885935338, "Hypovolaemic shock ": 3.105191578016871, "Infusion site erythema ": 5.242558021484332, "Infusion site phlebitis ": 15.2608525292957, "Infusion site pruritus ": 6.848978721640928, "International normalised ratio increased ": 3.105523449470476, "Joint noise ": 4.902634522660343, "Keratitis fungal ": 34.7178714916898, "Keratopathy ": 15.475580989096027, "Klebsiella infection ": 3.361512230636813, "Kounis syndrome ": 5.746158934209714, "Laryngeal oedema ": 3.267134094336276, "Leukocytosis ": 3.2606389958573483, "Lip oedema ": 2.899415331434075, "Liver injury ": 3.259464455551239, "Long QT syndrome ": 9.006782357675878, "Lung consolidation ": 6.1215352835389965, "Lymphocyte morphology abnormal ": 6.7073626316054105, "Macule ": 6.507771537663624, "Megacolon ": 7.53600144829206, "Meniscus injury ": 2.309812339610075, "Methaemoglobinaemia ": 11.068121497177764, "Mobility decreased ": 12.775584031504165, "Mucormycosis ": 3.066830280521802, "Multiple drug therapy ": 165.60940022887206, "Multiple organ dysfunction syndrome ": 3.0914899425731117, "Muscle discomfort ": 2.2214024857031087, "Muscle rupture ": 4.859420718124301, "Musculoskeletal injury ": 24.027052810713418, "Myoclonic epilepsy ": 2.6898893096576564, "Myopathy ": 2.014961036992792, "Nervous system disorder ": 2.07662505610088, "Neuropathy peripheral ": 2.7071694875020658, "Neutrophilia ": 2.789243798216206, "Nocardiosis ": 4.134828548791761, "Ocular icterus ": 2.935330170742204, "Off label use ": 2.2661199625667563, "Oliguria ": 5.929156138332552, "Orthostatic hypotension ": 38.08930896055659, "Oxygen saturation abnormal ": 4.117386491830603, "Painful ejaculation ": 53.04212209328095, "Palatal oedema ": 2.939626795196689, "Papule ": 2.499594359053298, "Paradoxical drug reaction ": 3.201428477403569, "Paranasal sinus inflammation ": 20.41497334503136, "Pathogen resistance ": 26.729323661118897, "Perineal pain ": 20.51317719429193, "Peripheral nerve injury ": 10.267746259537336, "Phlebitis ": 2.3874963180274995, "Plantar fasciitis ": 5.184190944825141, "Pneumocystis jirovecii pneumonia ": 2.092981062109333, "Pneumonia fungal ": 3.204626735886338, "Polymerase chain reaction positive ": 24.851458710209272, "Procalcitonin increased ": 5.82542853068188, "Prostatitis ": 2.6023625805693267, "Prothrombin time prolonged ": 3.934026653098589, "Prurigo ": 8.361147565363211, "Pruritus ": 2.312981168595094, "Pseudomembranous colitis ": 15.050348217150509, "Pseudomonas infection ": 4.15307960907002, "Pulmonary tuberculosis ": 4.925521034088022, "Purulent discharge ": 3.204513227314988, "Rash ": 2.0508538044839786, "Rash erythematous ": 2.997936605009793, "Rash maculo-papular ": 2.2374429924409056, "Renal function test abnormal ": 32.89275412285276, "Rhabdomyolysis ": 2.5545417796052305, "Rotator cuff syndrome ": 6.561657491677472, "Sedation ": 39.63139972347844, "Sedation complication ": 147.98221380379042, "Septic shock ": 3.405249312886684, "Skin erosion ": 2.2600491902214683, "Skin hyperpigmentation ": 3.136375666034769, "Skin infection ": 2.540034895548595, "Skin injury ": 5.488724777352484, "Sputum purulent ": 12.080150604444048, "Staphylococcal sepsis ": 2.4402485822393976, "Stenotrophomonas infection ": 6.038687055799206, "Stevens-Johnson syndrome ": 4.659642703872933, "Subcutaneous abscess ": 2.379752553670076, "Substance-induced psychotic disorder ": 6.24603698637604, "Tachypnoea ": 3.214377005780406, "Temperature intolerance ": 3.85459657672525, "Tendon discomfort ": 32.8117707554745, "Tendon disorder ": 27.97803066450283, "Tendon injury ": 20.835173229723043, "Tendon pain ": 50.72076838887962, "Tendon rupture ": 40.73205725739816, "Tendonitis ": 45.89371335963192, "Tenosynovitis ": 4.4358294418715785, "Torsade de pointes ": 10.294226857991136, "Toxic epidermal necrolysis ": 6.668429993556349, "Toxicity to various agents ": 5.370332413921644, "Transaminases increased ": 2.544695318097428, "Tuberculosis ": 3.663185332935721, "Tubulointerstitial nephritis ": 5.31491647360492, "Type I hypersensitivity ": 9.03871718309368, "Ventricular tachycardia ": 2.695293217748934}
\ No newline at end of file
+{"Adrenal insufficiency": 8.930942728376815, "Altered state of consciousness": 2.4799665845552, "Ammonia increased": 39.94253449630861, "Aortic dissection": 20.651641066753616, "Arterial haemorrhage": 34.065267325009586, "Ascites": 11.947432428003705, "Aspartate aminotransferase increased": 2.3196194220935644, "Blood albumin decreased": 10.562859355633238, "Blood bilirubin increased": 5.396399218810838, "Blood pressure increased": 3.8733840264720607, "Blood thyroid stimulating hormone increased": 14.456303508549514, "C-reactive protein increased": 4.443000622909988, "Cardiac failure": 4.313776821841689, "Cardiomyopathy": 2.9012502879927835, "Cerebral haemorrhage": 5.19294244221353, "Cerebral infarction": 6.638697528789071, "Cholangitis": 31.238836287333168, "Cholecystitis": 23.69378658833244, "Cholecystitis acute": 20.976946497177167, "Colitis": 2.12685117337769, "Decreased appetite": 11.406060673561353, "Dehydration": 2.944421692837881, "Diarrhoea": 3.537921085300144, "Disseminated intravascular coagulation": 2.846569099635216, "Drug eruption": 2.1347704191464043, "Duodenal perforation": 42.479587530942695, "Duodenal ulcer": 4.282201277694157, "Duodenal ulcer haemorrhage": 8.061933411146926, "Dysphonia": 7.856109076067763, "Ejection fraction decreased": 4.071966007755188, "Electrolyte imbalance": 2.8846279584939047, "Encephalopathy": 3.02890357611472, "Female genital tract fistula": 4.233363004187082, "Fistula": 31.70052200738032, "Gastric haemorrhage": 2.6897151412464675, "Gastrointestinal perforation": 40.12790119771768, "Generalised oedema": 2.045157432292528, "Gingivitis": 4.872605574255534, "Haematemesis": 2.7621038279843253, "Haemobilia": 47.64103992779931, "Haemoptysis": 4.824375820268939, "Hepatic encephalopathy": 128.29548863085378, "Hepatic failure": 8.739479561409487, "Hepatic function abnormal": 5.5269270061868045, "Hyperaesthesia": 6.203625348806715, "Hyperammonaemia": 11.82633170608136, "Hypercalcaemia": 2.2987456275342466, "Hypertension": 13.802272698783066, "Hypertensive crisis": 6.008694766639326, "Hyperthyroidism": 2.969415514403733, "Hypoalbuminaemia": 4.647739014787701, "Hypocalcaemia": 3.827131628437941, "Hypothyroidism": 18.639165602739286, "Impaired healing": 3.640410868017765, "Interstitial lung disease": 4.972714864401161, "Intestinal perforation": 11.51869585128959, "Jaundice": 3.657477694873463, "Large intestine perforation": 11.66486718706894, "Liver abscess": 13.400039871420544, "Liver carcinoma ruptured": 271.07394042044467, "Liver disorder": 4.174418119128023, "Malignant neoplasm progression": 7.298647799365376, "Mucosal inflammation": 6.065694936931237, "Nephrotic syndrome": 15.119008861741564, "Neutrophil count decreased": 2.076983816420066, "Oedema": 2.619798012002812, "Oedema peripheral": 2.1225844631932835, "Oesophageal varices haemorrhage": 45.64002112013237, "Osteonecrosis of jaw": 7.223543500335463, "Palmar-plantar erythrodysaesthesia syndrome": 31.71208721746813, "Peritonitis": 2.652979241113815, "Platelet count decreased": 8.30307116506572, "Pleural effusion": 2.925165891699881, "Pneumatosis intestinalis": 12.528553601031517, "Pneumonia aspiration": 2.722133455250781, "Pneumothorax": 10.744055730438356, "Polycythaemia": 27.482390398199648, "Portal vein thrombosis": 16.95733373696746, "Posterior reversible encephalopathy syndrome": 12.24705296816257, "Protein urine present": 22.02907929843787, "Proteinuria": 62.09274455717696, "Renal impairment": 2.8982816678613945, "Skin ulcer": 3.817334753552463, "Small intestinal perforation": 26.649858926258048, "Stomatitis": 6.3551049915749855, "Thyroiditis": 6.217118023287381, "Tracheal fistula": 526.8247248548116, "Transaminases increased": 2.089738661715584, "Tumour haemorrhage": 84.89722879375826, "Tumour lysis syndrome": 22.158735252069334, "Tumour rupture": 53.60569918896044, "Upper gastrointestinal haemorrhage": 2.073536346367236, "Weight decreased": 3.4954101867392464}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/661.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/661.json
index a3ff0555701..452f4c40424 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/661.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/661.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 12.824907575127687, "Colitis ": 6.518087400409695, "Death ": 2.7703912850880985, "Disease progression ": 12.637190316052566, "General physical health deterioration ": 4.029651328218883, "Hepatitis ": 7.803725110597868, "Hyperthyroidism ": 7.8545021524085055, "Hypothyroidism ": 16.56030425450857, "Interstitial lung disease ": 2.6902250626939685, "Malignant neoplasm progression ": 3.3511231171771247, "Myocarditis ": 6.679995533611112, "Myositis ": 24.899890572959738, "Neoplasm malignant ": 4.139028660434776, "Pemphigoid ": 24.370993007234965, "Pneumonitis ": 22.17963797527833, "Sepsis ": 2.984409222436762, "Squamous cell carcinoma of skin ": 71.47440420971948, "Type 1 diabetes mellitus ": 15.369091241456855}
\ No newline at end of file
+{"Myalgia": 3.369100339840505}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/662.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/662.json
index ef1d0355add..165efd36d9b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/662.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/662.json
@@ -1 +1 @@
-{"Cardiac arrest ": 71.16291199317672, "Cardio-respiratory arrest ": 35.994679443483, "Cerebrospinal fluid leakage ": 1023.2319110132846, "Completed suicide ": 87.47891839413673, "Death ": 5.5917204316085, "Implant site discharge ": 6734.374033975497, "Implant site extravasation ": 2690.8813664238464, "Muscle spasms ": 10.485525791662669, "Muscle spasticity ": 143.13476011750578, "Off label use ": 2.1547763096872536, "Suspected suicide ": 138.874140685055, "Therapeutic response decreased ": 44.45792970260735, "Toxicity to various agents ": 26.95828309183875}
\ No newline at end of file
+{"Hot flush": 15.19712763704767, "Malignant neoplasm progression": 8.509482013205686, "Prostate cancer": 46.12833308098613, "Prostatic specific antigen increased": 233.6534224817427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/663.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/663.json
index 9a000b14ccb..9506adf01dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/663.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/663.json
@@ -1 +1 @@
-{"Acute kidney injury ": 4.33109409472652, "Drug interaction ": 5.767175390918242, "Fall ": 2.930234974354311, "Hypoglycaemia ": 14.510139571270685, "Pemphigoid ": 60.263806054218286}
\ No newline at end of file
+{"Abortion spontaneous": 6.707283555729031, "Accident": 2.2695804879820294, "Accidental overdose": 2.731172718201436, "Anti-insulin antibody": 60.50790089146852, "Anti-insulin antibody increased": 42.23677836538053, "Anti-insulin antibody positive": 65.535456129277, "Arterial occlusive disease": 4.451726847975972, "Blindness": 4.996269848860576, "Blindness unilateral": 5.340403860424591, "Blood glucose abnormal": 15.896469709231988, "Blood glucose decreased": 29.185889943422477, "Blood glucose fluctuation": 49.33876671083628, "Blood glucose increased": 32.628955430001376, "Blood ketone body": 49.51578186783756, "Blood ketone body increased": 12.434047046898565, "Blood ketone body present": 33.400963248473296, "Caesarean section": 2.5722378764896843, "Cardiac operation": 8.342879689224205, "Cataract": 7.626624210248692, "Cataract operation": 11.118244393162406, "Cerebrovascular accident": 3.9299773128200495, "Coronary arterial stent insertion": 6.089304046374798, "Coronary artery bypass": 2.604397774343771, "Coronary artery occlusion": 3.3322823226738114, "Dementia": 3.5024643680462155, "Dementia Alzheimer's type": 7.022619150354636, "Dermatitis allergic": 2.032898520053178, "Device breakage": 38.121169651842486, "Device defective": 8.904560404107738, "Device delivery system issue": 11.085348981661967, "Device failure": 57.05664696677923, "Device information output issue": 61.77425229953794, "Device issue": 17.537552892008122, "Device leakage": 9.966689769277258, "Device malfunction": 30.102981042367105, "Device mechanical issue": 19.43735438959756, "Device occlusion": 7.442635674530234, "Diabetes mellitus inadequate control": 28.45059011529621, "Diabetic coma": 23.694001794678336, "Diabetic complication": 15.97055975674308, "Diabetic foot": 20.342181416544825, "Diabetic hyperglycaemic coma": 30.03849825117936, "Diabetic ketoacidosis": 18.386146715658228, "Diabetic ketosis": 18.22349013525297, "Diabetic metabolic decompensation": 21.72568252868372, "Diabetic nephropathy": 8.541014048919735, "Diabetic neuropathy": 12.642013555297089, "Diabetic retinopathy": 22.54277403965204, "Dialysis": 12.86628035665496, "Disability": 9.67096661392577, "Expired product administered": 4.756112543938508, "Exposure during pregnancy": 9.109919680866334, "Exposure via breast milk": 3.894602312382293, "Extra dose administered": 3.5811008046237145, "Eye haemorrhage": 3.069955587159581, "Eye operation": 5.945705847507709, "Fall": 2.108236265977693, "Foetal death": 3.14757917733095, "Foetal distress syndrome": 7.332867073113737, "Foetal exposure during pregnancy": 8.897600175521912, "Foetal growth restriction": 2.078376167552061, "Foetal macrosomia": 41.4308938806889, "Gangrene": 5.5318455819178665, "Gastric dilatation": 13.062758867167908, "Gestational hypertension": 10.428691246535964, "Glaucoma": 3.940642164446946, "Glycosylated haemoglobin abnormal": 18.287012638590863, "Glycosylated haemoglobin decreased": 16.061201896992877, "Glycosylated haemoglobin increased": 18.86236890446116, "Hepatic cirrhosis": 2.488783751751845, "Hip fracture": 2.323229185582808, "Hospitalisation": 3.6788286886646566, "Hyperglycaemia": 11.339378929373924, "Hyperglycaemic unconsciousness": 88.42910247616035, "Hyperinsulinaemic hypoglycaemia": 13.555503751415571, "Hypoglycaemia": 23.530696203986917, "Hypoglycaemia neonatal": 34.729448446951025, "Hypoglycaemia unawareness": 35.38262414628692, "Hypoglycaemic coma": 28.79667530632921, "Hypoglycaemic encephalopathy": 20.249479313150744, "Hypoglycaemic seizure": 42.52058456143703, "Hypoglycaemic unconsciousness": 66.2890344516306, "Incorrect dose administered": 2.4413861395697176, "Incorrect dose administered by device": 46.90037102727569, "Injection site atrophy": 93.29753353999894, "Injection site bruising": 9.22856888643478, "Injection site discolouration": 8.4850464379573, "Injection site erythema": 4.856849973283468, "Injection site extravasation": 4.395378198891554, "Injection site haemorrhage": 3.2028111417427683, "Injection site hypersensitivity": 44.45017244919512, "Injection site hypertrophy": 48.59655869007735, "Injection site induration": 11.30526718258914, "Injection site mass": 23.578521213624693, "Injection site nodule": 12.985660443342852, "Injection site oedema": 4.431426350858566, "Injection site pruritus": 8.739352866305511, "Injection site rash": 10.977259587727488, "Injection site reaction": 4.113885536368621, "Injection site swelling": 2.0638173664893213, "Injection site urticaria": 27.164223634210973, "Insulin resistance": 14.960270792980664, "Intentional dose omission": 6.965952669784408, "Intervertebral disc protrusion": 2.1366960269370567, "Jaundice neonatal": 41.36354391916744, "Ketoacidosis": 6.94826860401811, "Knee operation": 5.214180726339435, "Leg amputation": 17.196143931356495, "Lipoatrophy": 21.880162054446537, "Lipodystrophy acquired": 10.2413143839419, "Lipohypertrophy": 22.752987017699947, "Liquid product physical issue": 9.254691516370343, "Localised infection": 7.942854411488962, "Low birth weight baby": 3.628764780791176, "Lower limb fracture": 3.1441791997636392, "Macular degeneration": 4.951503391550416, "Maternal exposure during pregnancy": 6.406055516655634, "Myocardial infarction": 2.7523365090686305, "Needle issue": 2.66835686005716, "Neonatal respiratory distress syndrome": 6.965583677683898, "Neoplasm malignant": 2.439254043120021, "Osteomyelitis": 2.37644188856569, "Pancreatic carcinoma": 2.6325635629428947, "Parkinson's disease": 2.080073984659965, "Post procedural haemorrhage": 2.065882073576722, "Pre-eclampsia": 19.205853969283893, "Pregnancy": 3.310246598265455, "Premature baby": 12.028899986426014, "Premature delivery": 9.659672914885313, "Premature labour": 3.1515315199709484, "Product administration error": 2.4700163347647024, "Product communication issue": 20.145637157462776, "Product container issue": 17.111884658031975, "Product dispensing error": 4.630371690540557, "Product leakage": 7.7937799363659135, "Product physical issue": 10.354442810189456, "Product quality issue": 10.177586123153798, "Product storage error": 11.31216861890862, "Product use complaint": 5.0671834319604185, "Renal disorder": 2.325576743371893, "Renal transplant": 7.962074110426474, "Respiratory disorder neonatal": 29.518148860235986, "Retinopathy": 5.40247471335636, "Road traffic accident": 3.053204940129246, "Shock hypoglycaemic": 11.66906378464623, "Skin reaction": 3.3822057406815493, "Skin ulcer": 3.069590119648492, "Sopor": 2.266835462716338, "Spinal operation": 2.0873432966494376, "Spinal stenosis": 3.1762262921088857, "Staphylococcal infection": 2.171936236879832, "Stent placement": 2.959431759790387, "Stillbirth": 4.948490574036661, "Surgery": 3.093006892682557, "Toe amputation": 19.542138285371063, "Treatment noncompliance": 3.8635770853449967, "Ventricular septal defect": 4.343798979905995, "Weight increased": 2.0678920726264827, "Wheelchair user": 5.279897137202243, "Wrong product administered": 19.17095747440093, "Wrong technique in product usage process": 2.536381027493842}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/664.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/664.json
index 1ee07009a64..1c5af9a3a57 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/664.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/664.json
@@ -1 +1 @@
-{"Blood glucose abnormal ": 53.4575286452238, "Blood glucose fluctuation ": 41.27105490551752, "Blood glucose increased ": 87.89101787049886, "Drug ineffective ": 8.22141848052265, "Glycosylated haemoglobin increased ": 22.876231371127083, "Hyperglycaemia ": 6.932135829706606, "Hypoglycaemia ": 10.240657872103307, "Incorrect dose administered ": 41.996423895927954}
\ No newline at end of file
+{"Abnormal behaviour": 6.499697901118006, "Abortion induced": 3.8912446113691455, "Abortion spontaneous": 4.061530013123205, "Acidosis hyperchloraemic": 440.4716700362024, "Acute generalised exanthematous pustulosis": 2.915635530766832, "Acute hepatic failure": 4.581103047247436, "Acute psychosis": 12.312738919978113, "Adverse drug reaction": 2.524222450790091, "Affect lability": 5.242873019592547, "Affective disorder": 7.737605801786861, "Aggression": 12.187562621272214, "Agitation": 3.474589138694722, "Altered state of consciousness": 2.281512622524628, "Ammonia increased": 7.289186730475309, "Anger": 5.159217232548572, "Anticonvulsant drug level above therapeutic": 30.799991497847827, "Anticonvulsant drug level below therapeutic": 33.849691263280874, "Anticonvulsant drug level decreased": 21.300144797851804, "Anticonvulsant drug level increased": 12.941280590671036, "Anxiety disorder": 3.872946813867824, "Apathy": 3.215824000145393, "Apnoea": 3.6717342005658433, "Apnoeic attack": 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4.044566570875708, "Cerebral disorder": 2.050262731303567, "Change in seizure presentation": 33.00445893528884, "Cholestatic liver injury": 5.056525154829041, "Cleft palate": 3.658521851593559, "Clonic convulsion": 20.53755957175016, "Clonus": 2.4512112549588068, "Cognitive disorder": 5.90983230436221, "Completed suicide": 2.8115928000046866, "Condition aggravated": 2.5681435723474646, "Congenital anomaly": 4.2729897688882055, "Conjunctival hyperaemia": 2.1527398136336577, "Coordination abnormal": 3.885656072407611, "Culture urine positive": 20.55012709141713, "Delirium": 2.2967244584468376, "Delusion": 7.289089776186576, "Depressed mood": 2.294681625794916, "Depression": 2.1160099814550777, "Depressive symptom": 2.2593546973045444, "Dermatitis allergic": 2.295182024544755, "Developmental delay": 5.286067221187848, "Developmental hip dysplasia": 17.14280969596731, "Diabetic neuropathy": 4.293904056210915, "Disease recurrence": 2.780853434363451, "Drooling": 3.07628284858598, "Drop 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stimuli": 2.12484495181606, "Ventricular septal defect": 6.312468236404844, "Weight fluctuation": 2.1132996425311807, "Wrong patient received product": 2.218197256067405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/665.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/665.json
index d142e0fcb38..8ab665b2403 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/665.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/665.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.259240336738214, "Anxiety ": 10.2300050007786, "Asthma ": 18.868729602876517, "Constipation ": 2.2491851802209064, "Diabetes mellitus inadequate control ": 17.822798755797912, "Drug-induced liver injury ": 6.319059147574091, "Dry mouth ": 3.45381559092897, "Dyspnoea ": 3.7066066965968094, "Dyspnoea exertional ": 2.656328935660811, "Full blood count abnormal ": 88.59674363071399, "Gastrointestinal stoma complication ": 194.6685964208562, "Glycosylated haemoglobin increased ": 13.028983194478789, "Hyperglycaemia ": 2.461384559735168, "Hypoglycaemia ": 4.73612977433626, "Hypothyroidism ": 47.69135187261906, "Impaired healing ": 3.829771093948872, "Lactic acidosis ": 2.663629836207467, "Loss of personal independence in daily activities ": 37.39284053455656, "Obstructive airways disorder ": 152.46478997433735, "Pancreatitis ": 7.79640321688138, "Pancreatitis acute ": 13.412222145481731, "Sleep disorder due to a general medical condition ": 137.19558870950686, "Therapeutic product effect incomplete ": 35.85473670224807, "Weight decreased ": 2.3678388939648274, "Weight increased ": 2.329655448746052, "Wheezing ": 37.35591879695957}
\ No newline at end of file
+{"Malignant melanoma": 100.69410941559936, "Malignant melanoma in situ": 326.721474720663, "Vision blurred": 8.44443590716779}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/666.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/666.json
index 881e86f7f06..a2ef07d7288 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/666.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/666.json
@@ -1 +1 @@
-{"Cytokine release syndrome ": 608.0119262676772, "Pyrexia ": 3.739803912703095}
\ No newline at end of file
+{"Abnormal behaviour": 3.506483117110069, "Accidental overdose": 2.822563514884808, "Aggression": 2.058743224429961, "Agitation": 3.450032634703039, "Akinesia": 72.04836978935596, "Anxiety": 2.382816806697764, "Apathy": 14.09673920175693, "Balance disorder": 2.636679247003219, "Behaviour disorder": 5.929558998271033, "Blood creatine phosphokinase increased": 2.4012481087550515, "Bradykinesia": 35.247123554883295, "Cognitive disorder": 4.37768256367095, "Completed suicide": 2.3224432487173647, "Compulsive shopping": 252.64324083253203, "Condition aggravated": 2.567978954563276, "Delirium": 4.631684178419766, "Delusion": 19.5775776476232, "Dementia": 3.374356363861173, "Depressed mood": 2.7511959485787765, "Depression": 2.9537147464829743, "Dopamine dysregulation syndrome": 2264.228123339601, "Drug abuse": 3.159321513760441, "Drug dependence": 3.5291502802900347, "Drug interaction": 3.804613730635983, "Drug withdrawal syndrome": 4.847073654679399, "Dysarthria": 2.453991309162341, "Dyskinesia": 56.28044208587159, "Dysphagia": 2.202798262390475, "Dysphoria": 9.14877389115202, "Dystonia": 14.121036460241662, "Eating disorder": 5.543899076624224, "Encephalopathy": 3.995185386549276, "Extrapyramidal disorder": 4.9289084823178575, "Fall": 2.463175737439089, "Gait disturbance": 3.251714179364104, "Gambling disorder": 254.79365735789688, "Hallucination": 10.923715051688882, "Hallucination, auditory": 11.089738228310518, "Hallucination, tactile": 659.9624101125918, "Hallucination, visual": 34.39880764038122, "Hypersexuality": 259.0407640781477, "Hypokinesia": 5.186140096993126, "Hypomania": 19.62073852543799, "Hypotension": 2.221312727112009, "Hypothermia": 8.659507732707416, "Impulse-control disorder": 257.6020699368528, "Intentional overdose": 2.1956543299060334, "Intentional product misuse": 4.184631161899871, "Irritability": 3.0532151637333187, "Jealous delusion": 617.832767470861, "Labelled drug-disease interaction issue": 1272.462204249185, "Mood altered": 4.0301309454851015, "Motor dysfunction": 10.732357297884976, "Movement disorder": 7.844531657826774, "Muscle rigidity": 16.405095550951703, "Myoclonus": 10.331335123572996, "Neuroleptic malignant syndrome": 17.41257569686684, "Obsessive-compulsive disorder": 14.00328034366333, "On and off phenomenon": 850.806344389586, "Oromandibular dystonia": 128.2575176357359, "Orthostatic hypotension": 8.588162036144631, "Overdose": 2.327211917401294, "Paranoia": 12.369932604489309, "Paraphilia": 980.963496440671, "Parkinson's disease": 47.02115758391009, "Parkinsonian gait": 161.27818397582072, "Parkinsonism": 38.09030227816618, "Product administration error": 2.643930047773691, "Psychotic disorder": 10.037793525066412, "Restlessness": 3.786702710786704, "Somnolence": 2.498757694738578, "Speech disorder": 4.789574844356002, "Stereotypy": 185.73751418975763, "Therapeutic response shortened": 176.43122478116686, "Tremor": 2.4737682403122565, "Withdrawal syndrome": 4.537739524851074}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/667.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/667.json
index 26d08aaf1b9..414d36e5e24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/667.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/667.json
@@ -1 +1 @@
-{"Cutaneous vasculitis ": 84.4335224071629, "Hyperbilirubinaemia ": 45.972828608775394, "Neutropenia ": 4.505284177980844, "Off label use ": 3.0732478353406427, "Pruritus ": 2.360138812538991, "Rash ": 3.431970488380247, "Rash maculo-papular ": 72.23912974591937, "Toxic skin eruption ": 80.85767479288174}
\ No newline at end of file
+{"Acute generalised exanthematous pustulosis": 3.185896970238955, "Acute myelomonocytic leukaemia": 19.929477759064387, "Acute psychosis": 4.078015921779758, "Acute respiratory distress syndrome": 2.114462457888786, "Alanine aminotransferase abnormal": 2.206805703406878, "Alanine aminotransferase increased": 2.1704317457342133, "Anaphylactic shock": 2.8600696913968195, "Anaphylactoid reaction": 4.339155664456813, "Anion gap increased": 6.325101288809947, "Anterior chamber cell": 4.330932645903101, "Anterior chamber flare": 14.985443964804045, "Aspartate aminotransferase increased": 2.251269732275083, "Aspergillus infection": 2.2400627302207523, "Autoimmune haemolytic anaemia": 2.258233611589888, "Azotaemia": 2.000708110844585, "Bacteraemia": 3.4421397428492164, "Balance disorder": 13.240051789998628, "Blood calcium decreased": 88.39815108032741, "Blood calcium increased": 2.659245518796691, "Blood lactate dehydrogenase increased": 2.0997772187154022, "Brain abscess": 2.959032855212002, "Breath sounds abnormal": 2.6188524507329043, "Cardiac tamponade": 3.341324303727634, "Clostridium colitis": 11.967014628111576, "Clostridium difficile colitis": 7.427462400498184, "Clostridium difficile infection": 5.885202378777908, "Coagulation time prolonged": 2.2335253529142887, "Coagulopathy": 3.2867058664921647, "Cognitive disorder": 24.32292928059972, "Compartment syndrome": 2.7841164960330573, "Conjunctival hyperaemia": 3.309554031317577, "Constipation": 6.581123755934286, "Corneal oedema": 4.427213333271884, "Corneal perforation": 15.13815318750506, "Coronavirus test positive": 7.50158635129619, "Creatinine renal clearance decreased": 119.64661802092944, "Creatinine renal clearance increased": 99.68814009653433, "Cross sensitivity reaction": 5.448960625403972, "Crystal nephropathy": 33.975780759898925, "Delirium": 2.4341378884500124, "Depressed level of consciousness": 14.04192817570938, "Dermatitis": 2.5229068639521106, "Dermatitis allergic": 2.4472770576227223, "Dermatitis exfoliative": 2.6691112001115385, "Disorganised speech": 8.734730625978711, "Disseminated intravascular coagulation": 2.343479865828165, "Disseminated tuberculosis": 11.561574776586005, "Drug eruption": 5.2263780580674455, "Drug hypersensitivity": 2.875164651587066, "Drug ineffective for unapproved indication": 2.2300520511715605, "Drug interaction": 3.594016023568403, "Drug reaction with eosinophilia and systemic symptoms": 4.454503983966503, "Drug resistance": 5.01549074644675, "Drug-induced liver injury": 5.519678042500102, "Dysbiosis": 20.047662924042097, "Dysphoria": 2.072337523565461, "Electrocardiogram QT prolonged": 9.187658257577167, "Endophthalmitis": 3.498544422772712, "Eosinophil count increased": 2.4814225079434338, "Eosinophilic pneumonia": 4.488350824737814, "Eosinophilic pneumonia acute": 7.279558311811068, "Epidermal necrosis": 9.237013685439615, "Erythema multiforme": 2.6130436160115504, "Erythema nodosum": 2.13498120692078, "Erythema of eyelid": 2.3698189757266084, "Escherichia infection": 3.3109383656252813, "Face oedema": 2.33563398750285, "Fall": 4.502165030322142, "Fibrin": 281.7824941608508, "Fixed eruption": 14.21845248033594, "Gastrointestinal motility disorder": 4.398368534663399, "Granulocytopenia": 2.500471251929835, "Haemodynamic instability": 4.81228916830265, "Haemorrhage urinary tract": 2.193205997922832, "Hallucination, visual": 2.510652058993552, "Henoch-Schonlein purpura": 2.193205997922832, "Hepatic function abnormal": 4.9462667205434565, "Hepatitis acute": 4.615930768339785, "Hepatitis toxic": 2.9226748246634866, "Hepatocellular injury": 2.526827806843849, "Hepatosplenomegaly": 2.7674249090925427, "Hepatotoxicity": 2.784420395933539, "Hyperaemia": 7.24966933145107, "Hypersensitivity myocarditis": 16.741257951133942, "Hypersensitivity vasculitis": 3.4942947892279084, "Hypocoagulable state": 7.722997026076803, "Hypomagnesaemia": 3.0393107921064635, "Hypotension": 4.2626362906542825, "Hypovolaemic shock": 3.104633908140965, "Infusion site erythema": 5.241616493192903, "Infusion site phlebitis": 15.258111856376894, "Infusion site pruritus": 6.847748714381694, "International normalised ratio increased": 3.104965645030852, "Joint noise": 4.901754051696568, "Keratitis fungal": 34.71163656045561, "Keratopathy": 15.472801711570453, "Klebsiella infection": 3.3609085330345536, "Kounis syndrome": 5.745126986812363, "Laryngeal oedema": 3.266547313750875, "Leukocytosis": 3.260053373027667, "Lip oedema": 2.898894592924168, "Liver injury": 3.2588790244893646, "Long QT syndrome": 9.005164783356756, "Lung consolidation": 6.120435902584771, "Lymphocyte morphology abnormal": 6.706158065594662, "Macule": 6.5066027731076055, "Megacolon": 7.53464805309072, "Meniscus injury": 2.3093975223741285, "Methaemoglobinaemia": 11.066133741586894, "Mobility decreased": 12.773288828819776, "Mucormycosis": 3.0662795098348026, "Multiple drug therapy": 165.57965488429298, "Multiple organ dysfunction syndrome": 3.0909346724797357, "Muscle discomfort": 2.2210035449786303, "Muscle rupture": 4.858548004722016, "Musculoskeletal injury": 24.0227377771002, "Myoclonic epilepsy": 2.6894062359271564, "Myopathy": 2.014599162157199, "Nervous system disorder": 2.0762520920592222, "Neuropathy peripheral": 2.706600497275133, "Neutrophilia": 2.7887428791459663, "Nocardiosis": 4.134085978600161, "Ocular icterus": 2.9348030067304824, "Off label use": 2.2656230705015874, "Oliguria": 5.928091247710468, "Orthostatic hypotension": 38.07349086938439, "Oxygen saturation abnormal": 4.116647049055191, "Painful ejaculation": 53.03259614056082, "Palatal oedema": 2.9390988665922104, "Papule": 2.499145438150544, "Paradoxical drug reaction": 3.200853529403504, "Paranasal sinus inflammation": 20.41130703621289, "Pathogen resistance": 26.724522486820163, "Perineal pain": 20.50949321124564, "Peripheral nerve injury": 10.265902276962256, "Phlebitis": 2.3870675361416094, "Plantar fasciitis": 5.183259912473844, "Pneumocystis jirovecii pneumonia": 2.0926051730514024, "Pneumonia fungal": 3.2040512123830585, "Polymerase chain reaction positive": 24.84699561290264, "Procalcitonin increased": 5.824382344895901, "Prostatitis": 2.60189522449981, "Prothrombin time prolonged": 3.9333201067126735, "Prurigo": 8.359645973038802, "Pruritus": 2.312537426062003, "Pseudomembranous colitis": 15.047645058571865, "Pseudomonas infection": 4.152333735630167, "Pulmonary tuberculosis": 4.924636436529361, "Purulent discharge": 3.2039377315656603, "Rash": 2.0504570054459434, "Rash erythematous": 2.9973981148922286, "Rash maculo-papular": 2.237041115923636, "Renal function test abnormal": 32.88684619467331, "Rhabdomyolysis": 2.554082946782414, "Rotator cuff syndrome": 6.5604790059819, "Sedation": 39.62427969219826, "Sedation complication": 147.95562942702256, "Septic shock": 3.4046376938451046, "Skin erosion": 2.2596433071634223, "Skin hyperpigmentation": 3.1358123947609737, "Skin infection": 2.5395787244776584, "Skin injury": 5.487739044247254, "Sputum purulent": 12.07798111950329, "Staphylococcal sepsis": 2.4398103353176395, "Stenotrophomonas infection": 6.037602571048399, "Stevens-Johnson syndrome": 4.658805746753255, "Subcutaneous abscess": 2.3793251749323785, "Substance-induced psychotic disorder": 6.244915249959498, "Tachypnoea": 3.2133391386983625, "Temperature intolerance": 3.8539043084000606, "Tendon discomfort": 32.80587780917739, "Tendon disorder": 27.9730053577854, "Tendon injury": 20.83143110972921, "Tendon pain": 50.71165734159992, "Tendon rupture": 40.72473996524023, "Tendonitis": 45.88546836349259, "Tenosynovitis": 4.435032802057571, "Torsade de pointes": 10.29237788629443, "Toxic epidermal necrolysis": 6.667232230731926, "Toxicity to various agents": 5.369367564051924, "Transaminases increased": 2.5440814890789185, "Tuberculosis": 3.662527428515875, "Tubulointerstitial nephritis": 5.313961870764327, "Type I hypersensitivity": 9.037093802536065, "Ventricular tachycardia": 2.694809135382009}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/668.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/668.json
index 9e26dfeeb6e..c77dbfd7d8d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/668.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/668.json
@@ -1 +1 @@
-{}
\ No newline at end of file
+{"Adrenal insufficiency": 12.824907575127687, "Colitis": 6.518087400409695, "Death": 2.7703912850880985, "Disease progression": 12.637190316052566, "General physical health deterioration": 4.029651328218883, "Hepatitis": 7.803725110597868, "Hyperthyroidism": 7.853787427306609, "Hypothyroidism": 16.56030425450857, "Interstitial lung disease": 2.6902250626939685, "Malignant neoplasm progression": 3.3511231171771247, "Myocarditis": 6.679995533611112, "Myositis": 24.899890572959738, "Neoplasm malignant": 4.139028660434776, "Pemphigoid": 24.370993007234965, "Pneumonitis": 22.17963797527833, "Sepsis": 2.984409222436762, "Squamous cell carcinoma of skin": 71.47440420971948, "Type 1 diabetes mellitus": 15.369091241456855}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/669.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/669.json
index af4c52df716..516cb553602 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/669.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/669.json
@@ -1 +1 @@
-{"Death ": 6.995540191090403}
\ No newline at end of file
+{"Cardiac arrest": 69.60442238660464, "Cardio-respiratory arrest": 35.21183085038927, "Cerebrospinal fluid leakage": 982.757957706312, "Completed suicide": 85.5565137713835, "Death": 5.469983760491493, "Implant site discharge": 6588.100700844751, "Implant site extravasation": 2632.407900761736, "Muscle spasms": 10.257597744723563, "Muscle spasticity": 139.9871035119307, "Off label use": 2.107909053125125, "Suspected suicide": 135.8599384455892, "Therapeutic response decreased": 43.49127116200479, "Toxicity to various agents": 26.36915637278777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/67.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/67.json
index 4f991064141..fee39d49e70 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/67.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/67.json
@@ -1 +1 @@
-{"Abscess ": 7.868278144604589, "Abscess limb ": 23.63360683482409, "Acinetobacter infection ": 95.3788230832942, "Acoustic neuroma ": 89.69608075187472, "Acute generalised exanthematous pustulosis ": 5.658988385009125, "Acute kidney injury ": 4.214671752057169, "Alanine aminotransferase increased ": 2.8693614475672438, "Anticoagulation drug level above therapeutic ": 38.4740518413227, "Anuria ": 4.178088750542549, "Anxiety disorder ": 9.656380191759064, "Aspergillus infection ": 18.113661635648967, "Ataxia ": 2.071857426826283, "Atypical mycobacterial infection ": 45.750479287930375, "Atypical mycobacterium test positive ": 534.8625835358554, "Bacterial infection ": 4.606451117559942, "Blood albumin decreased ": 6.092170882102, "Brain abscess ": 26.55995398593603, "Bronchiectasis ": 10.289576518451682, "Bronchopulmonary aspergillosis ": 6.186924017394556, "Cachexia ": 9.841647946733753, "Candida infection ": 19.01015777720368, "Cheilitis ": 8.653335205272196, "Clostridium difficile colitis ": 19.65318733007692, "Clostridium difficile infection ": 4.058652063326903, "Condition aggravated ": 3.7208174939073615, "Congenital aplasia ": 28.562420385438894, "Cytomegalovirus infection ": 2.975346064102555, "Cytopenia ": 3.585680219840901, "Deafness ": 20.19182224680455, "Deafness bilateral ": 28.48454022944031, "Deafness neurosensory ": 49.65664319903518, "Depressive symptom ": 9.404026951051693, "Dermatitis ": 2.127572083275284, "Dermatitis exfoliative generalised ": 5.746425597486221, "Disease recurrence ": 6.960585413412245, "Disseminated mycobacterium avium complex infection ": 179.9172786839936, "Drug ineffective ": 3.25706331027822, "Drug ineffective for unapproved indication ": 7.270823552460221, "Drug intolerance ": 3.8688369079297513, "Drug reaction with eosinophilia and systemic symptoms ": 19.39997331861376, "Drug resistance ": 31.621807338038334, "Drug-induced liver injury ": 3.294324043817761, "Dysaesthesia ": 3.7800801003837576, "Electrocardiogram QT prolonged ": 7.218605522408021, "Electrolyte imbalance ": 6.020200806806434, "Encephalopathy ": 2.0985831552579417, "Enterococcal infection ": 79.11836155207891, "Eosinophilia ": 9.349164823905468, "Escherichia infection ": 11.186862530832292, "Escherichia sepsis ": 31.99014606105109, "Escherichia urinary tract infection ": 16.734222936633564, "Febrile neutropenia ": 2.0624746107322904, "Fungaemia ": 73.55685619394276, "Gamma-glutamyltransferase increased ": 3.0065535079785235, "Gastrointestinal disorder ": 2.2059134587911218, "Haematocrit decreased ": 3.892416527627805, "Haemodynamic instability ": 13.72693929803472, "Haemoptysis ": 2.5768331030786094, "Hepatic cytolysis ": 7.032462262712173, "Hepatic enzyme increased ": 3.0312665364121374, "Hepatic function abnormal ": 2.051119123426317, "Hepatitis ": 2.231844898558922, "Hepatotoxicity ": 5.232923293963265, "Hyperbilirubinaemia ": 4.180003636970371, "Hyperlactacidaemia ": 15.303986672376556, "Hypoacusis ": 5.5624242736819625, "Hypoalbuminaemia ": 6.738321961176094, "Hypogammaglobulinaemia ": 13.352707042156537, "Hypomagnesaemia ": 4.913407135136728, "Hypoproteinaemia ": 26.12155459479332, "Hypoxia ": 4.797577679130017, "Immune reconstitution inflammatory syndrome ": 6.272124571394586, "Inflammatory marker increased ": 14.389638833673551, "Intentional product use issue ": 3.1424090786547647, "Klebsiella infection ": 95.87163851363572, "Leukocytosis ": 3.0157308620725773, "Leukopenia ": 2.658030388210914, "Liver abscess ": 15.503320153638995, "Lung transplant rejection ": 86.75445446744452, "Lymphadenitis ": 2.9672722226590413, "Lymphopenia ": 3.1734161064888395, "Metabolic acidosis ": 3.01167565933921, "Microangiopathic haemolytic anaemia ": 70.77640694401363, "Moraxella infection ": 234.4438383409893, "Mucormycosis ": 25.668700284221813, "Multiple organ dysfunction syndrome ": 7.609418994484369, "Multiple-drug resistance ": 9.484347282901172, "Mycobacterial infection ": 51.05499789923144, "Mycobacterium abscessus infection ": 644.3524522687882, "Mycobacterium avium complex infection ": 208.6702244361007, "Neonatal candida infection ": 1321.3792121936094, "Nephropathy toxic ": 18.60198113024841, "Neuropathy peripheral ": 2.56030194212509, "Nodule ": 4.606356276354017, "Off label use ": 2.241205505901953, "Oliguria ": 4.12182206682986, "Optic neuritis ": 8.628884490105358, "Otitis media ": 9.069150587417631, "Ototoxicity ": 275.40436637700014, "Pancytopenia ": 2.3218026713617226, "Pathogen resistance ": 47.53185946752846, "Pleurisy ": 6.735529907934369, "Polyp ": 8.723592742098521, "Product prescribing error ": 4.222294779045326, "Product use in unapproved indication ": 3.434552160653675, "Proteus infection ": 120.9803622922906, "Pseudomembranous colitis ": 6.97841915403745, "Pseudomonas infection ": 22.172232147919782, "Pulmonary cavitation ": 49.7260167254742, "Pulmonary haemorrhage ": 11.089191250638232, "Pulmonary mass ": 5.923889203078185, "Pyelonephritis ": 4.239618964789491, "Rash erythematous ": 2.219900181749688, "Rash maculo-papular ": 8.859653169574724, "Rash morbilliform ": 2.793935905518331, "Red blood cell sedimentation rate increased ": 3.918920902624868, "Renal impairment ": 2.0960871129045366, "Renal tubular necrosis ": 3.884189364934071, "Respiratory distress ": 3.08836736286121, "Respiratory failure ": 3.229233495176351, "Sepsis ": 3.3722477685664174, "Septic shock ": 8.943578777579065, "Shock ": 4.433847037674333, "Skin lesion ": 3.640030679547249, "Staphylococcal infection ": 3.1385542133827, "Staphylococcal sepsis ": 9.81378396551248, "Stevens-Johnson syndrome ": 3.107716393098529, "Streptococcal infection ": 17.30427004045918, "Systemic candida ": 44.04506161520125, "Therapy non-responder ": 3.1886694767922874, "Thrombocytopenia ": 3.252351557203704, "Tinnitus ": 2.754651579354128, "Toxic epidermal necrolysis ": 2.5171902050598183, "Transaminases increased ": 3.188704852199632, "Transplant rejection ": 11.040073635175988, "Treatment failure ": 5.479122433260497, "Tuberculosis ": 10.360097953491495}
\ No newline at end of file
+{"Abdominal pain": 3.5536962539599477, "Anaphylactic reaction": 12.494737353107771, "Ankylosing spondylitis": 77.00569225346163, "Asthenia": 2.3092256701979856, "Crohn's disease": 23.02394832891432, "Drug ineffective": 4.170803770484257, "Drug intolerance": 10.769092597570276, "Dry eye": 84.92637032176326, "General symptom": 636.8802479283545, "Inflammation": 19.847935195390995, "Lacrimation increased": 80.34816352545491, "Loss of personal independence in daily activities": 15.492275192477829, "Oedema": 15.39793789286796, "Pain in extremity": 2.3274996032749025, "Pelvic pain": 114.10303948665126, "Plantar fasciitis": 905.5877671046986, "Psoriasis": 41.23265456712485, "Synovitis": 45.02311945131504, "Tendonitis": 91.50465489607292, "Therapeutic product effect incomplete": 14.748424972215682, "Therapy non-responder": 21.989814889580988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/670.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/670.json
index abbe26afe0a..72c18633490 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/670.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/670.json
@@ -1 +1 @@
-{"Activated partial thromboplastin time prolonged ": 4.705462149717445, "Alopecia ": 2.686328531706262, "Anaemia ": 6.796587796311269, "Anal haemorrhage ": 21.132663684390533, "Atrial thrombosis ": 51.04701895647843, "Basal ganglia haemorrhage ": 30.532326583342925, "Bleeding time prolonged ": 25.243346701233516, "Blood loss anaemia ": 7.305957493458125, "Blood pressure decreased ": 2.199693311849252, "Blood urine present ": 35.401728374591656, "Cerebellar haemorrhage ": 26.738081360684, "Cerebral haemorrhage ": 18.79735478375084, "Cerebral infarction ": 6.839039001373485, "Cerebral ischaemia ": 9.805514585996791, "Cerebrovascular accident ": 4.711151968334206, "Chromaturia ": 3.146456318444303, "Colon cancer ": 3.930055850722903, "Conjunctival haemorrhage ": 10.076311803848563, "Contusion ": 2.60595841247187, "Dermatitis allergic ": 2.287985239180357, "Diverticulum intestinal haemorrhagic ": 20.619695137050822, "Duodenal ulcer ": 4.25094939236723, "Duodenal ulcer haemorrhage ": 8.003096730405808, "Ecchymosis ": 3.197845709891234, "Embolic stroke ": 25.81648769626895, "Epistaxis ": 19.17672143604868, "Eye haemorrhage ": 11.539768936071326, "Faeces discoloured ": 9.728128382810135, "Femoral neck fracture ": 6.819362956609835, "Gamma-glutamyltransferase increased ": 4.238830062019366, "Gastric haemorrhage ": 15.098828263106984, "Gastric ulcer haemorrhage ": 7.031904197190437, "Gastrointestinal haemorrhage ": 10.461450232395146, "Gingival bleeding ": 16.23723168019448, "Glomerular filtration rate decreased ": 5.076442554601303, "Haemarthrosis ": 11.77876017032896, "Haematemesis ": 4.907429352664151, "Haematochezia ": 7.792203544167881, "Haematoma ": 11.008780161986602, "Haematoma muscle ": 6.914985491947554, "Haematuria ": 22.550060663647884, "Haemoglobin decreased ": 4.208749713484409, "Haemoptysis ": 4.789159600438884, "Haemorrhage ": 7.066698727829784, "Haemorrhage intracranial ": 5.92703356924056, "Haemorrhage subcutaneous ": 9.625573609595731, "Haemorrhage urinary tract ": 7.682373977381654, "Haemorrhagic diathesis ": 6.808872444652647, "Haemorrhagic stroke ": 6.301820941326927, "Haemorrhoidal haemorrhage ": 12.95557426756336, "Hemiparesis ": 6.195765618403061, "Incorrect dose administered ": 20.41426748653862, "International normalised ratio increased ": 2.9090200625299394, "Intestinal haemorrhage ": 50.37330192525222, "Intraventricular haemorrhage ": 13.1756080849217, "Iron deficiency anaemia ": 11.553149135982896, "Ischaemic stroke ": 9.215540370567451, "Labelled drug-drug interaction medication error ": 2.7724472863580587, "Liver function test increased ": 3.2074843020773915, "Lower gastrointestinal haemorrhage ": 17.50273654570032, "Melaena ": 20.43457538005694, "Mouth haemorrhage ": 15.50421722005541, "Muscle haemorrhage ": 8.788041150014225, "Petechiae ": 3.082395822676621, "Post procedural haemorrhage ": 11.79132078421702, "Prescribed underdose ": 2.2922989361270742, "Product dose omission in error ": 5.319145280218994, "Product prescribing error ": 5.28942153508757, "Product residue present ": 12.95337182245376, "Prothrombin time prolonged ": 10.43832557775457, "Pruritus ": 3.2675712274472994, "Pulmonary embolism ": 2.609819612221366, "Purpura ": 3.008567848157621, "Rash macular ": 2.159497208530759, "Rash morbilliform ": 2.5655028597435705, "Rash pruritic ": 2.15863090811535, "Rash pustular ": 4.269600279974583, "Rectal haemorrhage ": 14.00433180472529, "Renal function test abnormal ": 9.606183613855508, "Renal haemorrhage ": 13.868630299621929, "Shock haemorrhagic ": 10.4689188616605, "Skin discolouration ": 2.1109261913051243, "Skin haemorrhage ": 25.59641644629596, "Small intestinal haemorrhage ": 22.434968652812653, "Subarachnoid haemorrhage ": 7.023625928807696, "Subcutaneous haematoma ": 7.930173410645819, "Subdural haematoma ": 9.90758528625753, "Thalamus haemorrhage ": 44.3668783129533, "Therapy cessation ": 3.9256694180937184, "Thrombosis ": 2.186727757315752, "Transient ischaemic attack ": 3.9484359472683495, "Treatment noncompliance ": 2.443507723054619, "Type IV hypersensitivity reaction ": 11.464208883399063, "Underdose ": 7.08269592862228, "Upper gastrointestinal haemorrhage ": 9.888523175927004, "Urethral haemorrhage ": 43.30575831966736, "Urinary bladder haemorrhage ": 44.1060183245777, "Vaginal haemorrhage ": 4.409942861292236, "Wound haemorrhage ": 12.236597067269292, "Wrong technique in product usage process ": 4.600057914450002}
\ No newline at end of file
+{"Acute kidney injury": 4.33109409472652, "Drug interaction": 5.767175390918242, "Fall": 2.930159868168801, "Hypoglycaemia": 14.509649698233726, "Pemphigoid": 60.263806054218286}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/671.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/671.json
index 99a569dc051..cfbdd5a6b90 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/671.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/671.json
@@ -1 +1 @@
-{"Hypokalaemia ": 46.09987669538091}
\ No newline at end of file
+{"Blood glucose abnormal": 53.4575286452238, "Blood glucose fluctuation": 41.27105490551752, "Blood glucose increased": 87.89101787049886, "Drug ineffective": 8.221357696864517, "Glycosylated haemoglobin increased": 22.876231371127083, "Hyperglycaemia": 6.932135829706606, "Hypoglycaemia": 10.240312160809149, "Incorrect dose administered": 41.996423895927954}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/672.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/672.json
index 3c2bc737e9c..8a442861666 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/672.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/672.json
@@ -1 +1 @@
-{"Febrile neutropenia ": 23.38206119690035, "Nausea ": 2.6557462838163506, "Neutropenia ": 8.457726457204446}
\ No newline at end of file
+{"Acute kidney injury": 2.2558671532728463, "Anxiety": 10.214700734503449, "Asthma": 18.84050315666232, "Constipation": 2.2458279340043363, "Diabetes mellitus inadequate control": 17.796183174987, "Drug-induced liver injury": 6.309243143323618, "Dry mouth": 3.4486607344819453, "Dyspnoea": 3.7010064592768175, "Dyspnoea exertional": 2.652365989425141, "Full blood count abnormal": 88.46421785977161, "Gastrointestinal stoma complication": 194.37817882313828, "Glycosylated haemoglobin increased": 13.009536707015313, "Hyperglycaemia": 2.457711682994829, "Hypoglycaemia": 4.728896285801191, "Hypothyroidism": 47.62001282654, "Impaired healing": 3.824057503771781, "Lactic acidosis": 2.659655997846512, "Loss of personal independence in daily activities": 37.336905618185625, "Obstructive airways disorder": 152.2367325114175, "Pancreatitis": 7.784761019664484, "Pancreatitis acute": 13.392195914457334, "Sleep disorder due to a general medical condition": 136.99039134176954, "Therapeutic product effect incomplete": 35.80110188140232, "Weight decreased": 2.364303748408271, "Weight increased": 2.3261781943265776, "Wheezing": 37.298549021719374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/673.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/673.json
index a355db77653..e1450d2d910 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/673.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/673.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.029979046351197, "Alopecia ": 2.278752816790884, "Anaemia ": 7.917730241563449, "Ascites ": 6.352302478703547, "Bacteraemia ": 3.005459280679409, "Biliary obstruction ": 31.98337498721818, "Blood bilirubin increased ": 2.6460735743371093, "Blood potassium decreased ": 2.0863835900605374, "Cancer pain ": 22.77968776464956, "Carbohydrate antigen 19-9 increased ": 42.57335920705888, "Carcinoembryonic antigen increased ": 42.55156315410201, "Chromaturia ": 4.276619544596277, "Colon cancer ": 7.129126715469529, "Colon cancer metastatic ": 27.655400712636325, "Colorectal cancer metastatic ": 31.77209285306245, "Constipation ": 3.0480924006547734, "Cytopenia ": 13.812080230516608, "Death ": 11.340613591005068, "Decreased appetite ": 4.048070830752336, "Dehydration ": 4.588668462598244, "Diarrhoea ": 3.075102886713893, "Disease progression ": 33.53438385997516, "Dysphonia ": 2.201331234690422, "Febrile neutropenia ": 9.407784526088236, "Feeding disorder ": 2.7428534297056557, "Full blood count abnormal ": 6.023692379471247, "Gastrointestinal toxicity ": 8.75236664587835, "General physical health deterioration ": 2.427989080984312, "Haematotoxicity ": 7.130697356303676, "Haemoglobin decreased ": 3.645895770628058, "Hepatic failure ": 3.0403359611977687, "Hospitalisation ": 7.42618719347173, "Hydronephrosis ": 5.704149244143079, "Hyperbilirubinaemia ": 2.556312633099909, "Hypophagia ": 2.41741965171428, "Inappropriate schedule of product administration ": 8.573613017843925, "Intentional product use issue ": 6.709232006755912, "Intercepted product prescribing error ": 50.29835026126475, "Intestinal obstruction ": 9.856655872826012, "Intra-abdominal fluid collection ": 22.33568371094168, "Jaundice ": 2.7572258199978266, "Large intestinal obstruction ": 35.05839673789991, "Leukocytosis ": 2.549562938245106, "Leukopenia ": 7.582926750515908, "Malignant neoplasm progression ": 5.398532703412329, "Metastases to central nervous system ": 2.7283763054667407, "Metastases to liver ": 2.0058006572712084, "Metastases to lung ": 2.995133353364316, "Nausea ": 2.018168492003554, "Neutropenia ": 17.474663003731553, "Neutrophil count decreased ": 4.345476928298887, "No adverse event ": 2.6711274281813404, "Onychoclasis ": 13.521904378026498, "Palmar-plantar erythrodysaesthesia syndrome ": 2.95466344205187, "Pancytopenia ": 4.316328080531182, "Performance status decreased ": 11.054507460595712, "Platelet count decreased ": 3.300458465927376, "Prescribed underdose ": 12.061890520799398, "Product availability issue ": 42.75693475670063, "Product prescribing error ": 2.4059803976167813, "Product use issue ": 3.912583577097015, "Red blood cell count decreased ": 8.974819528740571, "Septic shock ": 2.000584116995454, "Small intestinal obstruction ": 13.558433677410653, "Surgery ": 2.298846964427156, "Taste disorder ": 2.652450755374248, "Terminal state ": 8.481058799994022, "Thrombocytopenia ": 4.577310986305621, "Transfusion ": 11.417484940528787, "Umbilical hernia ": 13.986086143251596, "Urinary tract infection ": 3.0301102318131417, "Vomiting ": 2.332975531476016, "Weight decreased ": 3.198387762034814, "White blood cell count decreased ": 6.711295721444728}
\ No newline at end of file
+{"Cytokine release syndrome": 608.0119262676772, "Pyrexia": 3.739724047307549}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/674.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/674.json
index f26b1714e9a..3e2215b9036 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/674.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/674.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 6.956339370450681, "Acute kidney injury ": 3.6425025113918186, "Adrenal insufficiency ": 6.978243687677841, "Adrenal suppression ": 156.4809383579694, "Adverse event ": 2.019915985538593, "Atrial flutter ": 11.802625291371566, "Blood alkaline phosphatase increased ": 2.5878602535121797, "COVID-19 pneumonia ": 7.491260487825665, "Candida infection ": 12.82948398275084, "Condition aggravated ": 2.139572638776511, "Cortisol decreased ": 63.88734121257639, "Cushing's syndrome ": 105.20007554066, "Cushingoid ": 68.69768971000836, "Diarrhoea ": 3.3930337253476712, "Drug effective for unapproved indication ": 23.15583204073633, "Drug ineffective for unapproved indication ": 10.756095552634152, "Drug interaction ": 19.2779277272622, "Drug level increased ": 24.697288336057355, "Drug resistance ": 4.345861685581512, "Drug-induced liver injury ": 2.8384233240783527, "Dyslipidaemia ": 77.72601850586496, "Electrocardiogram QT prolonged ": 19.46770830627825, "Eosinophilia ": 5.169270037166421, "Ergot poisoning ": 975.2989695225376, "Fanconi syndrome ": 58.01298889648041, "Fanconi syndrome acquired ": 39.43054365765786, "Foetal exposure during pregnancy ": 4.427723039245703, "Glycosuria ": 35.58593287566713, "Haematotoxicity ": 16.872814125327896, "Hepatotoxicity ": 9.5417665369948, "Hypertransaminasaemia ": 8.017078428876976, "Hypertriglyceridaemia ": 11.817173113705076, "Hypophosphataemia ": 18.08519207367095, "Immune reconstitution inflammatory syndrome ": 26.73939425175821, "Live birth ": 20.073412454885304, "Liver injury ": 5.1131599920309325, "Maternal exposure during pregnancy ": 4.345046649392438, "Metabolic acidosis ": 4.680288115825212, "Nephropathy toxic ": 8.660594485151726, "Off label use ": 10.433717251621257, "Osteomalacia ": 18.556647484457045, "Osteonecrosis ": 2.0338300867947376, "Osteopenia ": 2.5747566297293845, "Peripheral coldness ": 6.4214541091289385, "Peripheral pulse decreased ": 462.791873582706, "Pre-existing condition improved ": 293.05930324646465, "Premature delivery ": 7.891521505746379, "Proteinuria ": 3.793714298007711, "Rash maculo-papular ": 5.338574269806249, "Rash pruritic ": 2.489206781912797, "Renal tubular acidosis ": 43.23160786116027, "Renal tubular necrosis ": 11.588157897095549, "Respiratory failure ": 2.272999172347475, "Rhabdomyolysis ": 3.0968893244153524, "Sinus bradycardia ": 9.80438030452272, "Skin striae ": 102.15224174216333, "Stress fracture ": 37.52594035680793, "Supraventricular tachycardia ": 7.370417183420508, "Therapeutic product effect incomplete ": 3.5712745872998157, "Therapeutic response unexpected ": 36.709231936076414, "Virologic failure ": 20.037287515319957, "Weight increased ": 2.6549636639047707}
\ No newline at end of file
+{"Cutaneous vasculitis": 84.4335224071629, "Hyperbilirubinaemia": 45.972828608775394, "Neutropenia": 4.505090464213991, "Off label use": 3.0731267971585057, "Pruritus": 2.3601102272449324, "Rash": 3.431923347159329, "Rash maculo-papular": 72.23912974591937, "Toxic skin eruption": 80.85767479288174}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/675.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/675.json
index 695aff660cf..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/675.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/675.json
@@ -1 +1 @@
-{"Diarrhoea ": 10.615012529823211, "Hepatic cytolysis ": 122.11118204794056}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/676.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/676.json
index bb90177670f..9fc1e8c8eb3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/676.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/676.json
@@ -1 +1 @@
-{"Agitation ": 4.017740379748436, "Altered state of consciousness ": 7.47240532226129, "Cardiogenic shock ": 25.85309436914321, "Coma ": 8.690055686184495, "Completed suicide ": 2.830872298326427, "Condition aggravated ": 3.7307338277763296, "Death ": 2.414109899985138, "Drug abuse ": 15.312618666358835, "Drug ineffective ": 2.4122143516411683, "Drug interaction ": 2.8926850481260464, "Drug resistance ": 16.684796681170937, "Extrapyramidal disorder ": 17.46911214507023, "Generalised tonic-clonic seizure ": 14.50084368750199, "Hypocalcaemia ": 28.709133522073564, "Hypoparathyroidism ": 532.6009034077952, "Hypotension ": 2.967662823140212, "Mental disorder ": 9.37636320254358, "Muscle twitching ": 12.193786743794403, "Myoclonus ": 32.00133395568836, "Neuroleptic malignant syndrome ": 22.794503539131547, "Overdose ": 6.888201236158349, "Parkinsonism ": 34.10754488140372, "Poisoning ": 64.84474681924394, "Poisoning deliberate ": 59.6502768504546, "Product use in unapproved indication ": 2.804162695976544, "Pulmonary embolism ": 2.5113314247839105, "Sedation ": 14.53558252909778, "Seizure ": 2.501151490031622, "Somnolence ": 3.003379631822912, "Suicide attempt ": 5.288660770896732, "Tardive dyskinesia ": 54.984589144793546, "Toxicity to various agents ": 6.251686584021923, "Treatment failure ": 13.916666631202588, "Weight increased ": 2.1533362830076164}
\ No newline at end of file
+{"Death": 6.995540191090403}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/677.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/677.json
index 3100a0e40eb..fc0ca018577 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/677.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/677.json
@@ -1 +1 @@
-{"Eye irritation ": 27.923730388082124, "Eye pain ": 17.82701144203305, "Vision blurred ": 4.530590928327984, "Visual acuity reduced ": 38.290648912713706, "Visual impairment ": 5.673552456338943, "Vitreous floaters ": 50.7839591065242}
\ No newline at end of file
+{"Activated partial thromboplastin time prolonged": 4.705462149717445, "Alopecia": 2.686328531706262, "Anaemia": 6.796587796311269, "Anal haemorrhage": 21.132663684390533, "Atrial thrombosis": 51.04701895647843, "Basal ganglia haemorrhage": 30.532326583342925, "Bleeding time prolonged": 25.243346701233516, "Blood loss anaemia": 7.305957493458125, "Blood pressure decreased": 2.199621848845156, "Blood urine present": 35.401728374591656, "Cerebellar haemorrhage": 26.738081360684, "Cerebral haemorrhage": 18.79735478375084, "Cerebral infarction": 6.839039001373485, "Cerebral ischaemia": 9.805514585996791, "Cerebrovascular accident": 4.711066856801816, "Chromaturia": 3.146456318444303, "Colon cancer": 3.930055850722903, "Conjunctival haemorrhage": 10.076311803848563, "Contusion": 2.60595841247187, "Dermatitis allergic": 2.287985239180357, "Diverticulum intestinal haemorrhagic": 20.619695137050822, "Duodenal ulcer": 4.25094939236723, "Duodenal ulcer haemorrhage": 8.003096730405808, "Ecchymosis": 3.197845709891234, "Embolic stroke": 25.81648769626895, "Epistaxis": 19.17672143604868, "Eye haemorrhage": 11.539768936071326, "Faeces discoloured": 9.728128382810135, "Femoral neck fracture": 6.819362956609835, "Gamma-glutamyltransferase increased": 4.238830062019366, "Gastric haemorrhage": 15.098828263106984, "Gastric ulcer haemorrhage": 7.031904197190437, "Gastrointestinal haemorrhage": 10.461450232395146, "Gingival bleeding": 16.23723168019448, "Glomerular filtration rate decreased": 5.076442554601303, "Haemarthrosis": 11.77876017032896, "Haematemesis": 4.9069930310897645, "Haematochezia": 7.79142977927386, "Haematoma": 11.008780161986602, "Haematoma muscle": 6.914985491947554, "Haematuria": 22.550060663647884, "Haemoglobin decreased": 4.208749713484409, "Haemoptysis": 4.789159600438884, "Haemorrhage": 7.066698727829784, "Haemorrhage intracranial": 5.92703356924056, "Haemorrhage subcutaneous": 9.625573609595731, "Haemorrhage urinary tract": 7.682373977381654, "Haemorrhagic diathesis": 6.808872444652647, "Haemorrhagic stroke": 6.301820941326927, "Haemorrhoidal haemorrhage": 12.95557426756336, "Hemiparesis": 6.194982430785515, "Incorrect dose administered": 20.41426748653862, "International normalised ratio increased": 2.9090200625299394, "Intestinal haemorrhage": 50.37330192525222, "Intraventricular haemorrhage": 13.1756080849217, "Iron deficiency anaemia": 11.549025938002483, "Ischaemic stroke": 9.215540370567451, "Labelled drug-drug interaction medication error": 2.7724472863580587, "Liver function test increased": 3.2074843020773915, "Lower gastrointestinal haemorrhage": 17.50273654570032, "Melaena": 20.43191077283921, "Mouth haemorrhage": 15.50421722005541, "Muscle haemorrhage": 8.788041150014225, "Petechiae": 3.082395822676621, "Post procedural haemorrhage": 11.79132078421702, "Prescribed underdose": 2.2922989361270742, "Product dose omission in error": 5.319145280218994, "Product prescribing error": 5.28942153508757, "Product residue present": 12.95337182245376, "Prothrombin time prolonged": 10.43832557775457, "Pruritus": 3.2675315794206585, "Pulmonary embolism": 2.609819612221366, "Purpura": 3.008567848157621, "Rash macular": 2.159497208530759, "Rash morbilliform": 2.5655028597435705, "Rash pruritic": 2.15863090811535, "Rash pustular": 4.269600279974583, "Rectal haemorrhage": 14.00433180472529, "Renal function test abnormal": 9.606183613855508, "Renal haemorrhage": 13.868630299621929, "Shock haemorrhagic": 10.4689188616605, "Skin discolouration": 2.1109261913051243, "Skin haemorrhage": 25.5875690470194, "Small intestinal haemorrhage": 22.434968652812653, "Subarachnoid haemorrhage": 7.023625928807696, "Subcutaneous haematoma": 7.930173410645819, "Subdural haematoma": 9.90758528625753, "Thalamus haemorrhage": 44.3668783129533, "Therapy cessation": 3.9256694180937184, "Thrombosis": 2.186727757315752, "Transient ischaemic attack": 3.9484359472683495, "Treatment noncompliance": 2.443507723054619, "Type IV hypersensitivity reaction": 11.464208883399063, "Underdose": 7.08269592862228, "Upper gastrointestinal haemorrhage": 9.885824365975452, "Urethral haemorrhage": 43.30575831966736, "Urinary bladder haemorrhage": 44.1060183245777, "Vaginal haemorrhage": 4.409942861292236, "Wound haemorrhage": 12.236597067269292, "Wrong technique in product usage process": 4.600057914450002}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/678.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/678.json
index fbc2706b960..12f15ea5a40 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/678.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/678.json
@@ -1 +1 @@
-{"Drug interaction ": 42.273599806397776, "Drug level decreased ": 575.3483451786454}
\ No newline at end of file
+{"Hypokalaemia": 46.09987669538091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/679.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/679.json
index a919988dece..f285d8f76ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/679.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/679.json
@@ -1 +1 @@
-{"Corneal opacity ": 533.1505615899403, "Fall ": 5.402952654642398, "Intraocular pressure increased ": 159.09026808163892}
\ No newline at end of file
+{"Febrile neutropenia": 23.38206119690035, "Nausea": 2.655734164597162, "Neutropenia": 8.457362804810092}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/68.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/68.json
index c1631bf40f1..b8d95f7cd22 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/68.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/68.json
@@ -1 +1 @@
-{"Abdominal pain ": 3.3437141919860025, "Adjustment disorder with depressed mood ": 32.407784685791746, "Adverse drug reaction ": 6.645147571515391, "Adverse event ": 4.685938319955347, "Alcohol poisoning ": 5.001489980624515, "Amnesia ": 3.808849611886302, "Anaemia ": 7.750340702567592, "Anti-cyclic citrullinated peptide antibody positive ": 5.830572715093489, "Arterial disorder ": 7.441972642488024, "Arthritis ": 2.52395774711242, "Arthropathy ": 2.329512758318693, "Arthropod bite ": 12.697509728922162, "Aspartate aminotransferase increased ": 2.460328287989767, "Bicytopenia ": 6.118621922607735, "Blister ": 2.0876604707061373, "Blood albumin decreased ": 12.896221370899845, "Blood calcium decreased ": 15.655533377231198, "Blood cholesterol increased ": 3.5520433046379, "Blood creatinine decreased ": 10.297877025771236, "Blood magnesium decreased ": 18.28801422372262, "Blood potassium decreased ": 4.896853183101811, "Blood sodium decreased ": 8.781584017184526, "Bone erosion ": 4.016127326760983, "Breast cancer stage III ": 27.97891107944217, "Bursitis ": 6.197631907260624, "C-reactive protein abnormal ": 7.442237717755549, "Cardiopulmonary failure ": 6.054997755175523, "Chronic sinusitis ": 100.3854824212843, "Colitis ": 27.556620337887317, "Colitis ulcerative ": 41.42627502497341, "Constipation ": 6.48903639271728, "Contusion ": 2.118331954108597, "Cor pulmonale ": 11.711072825290394, "Deafness bilateral ": 5.612989687967537, "Deafness neurosensory ": 3.975890909407739, "Deep vein thrombosis postoperative ": 5.136803969116341, "Delirium ": 3.3374459652188064, "Dengue fever ": 9.010566589529642, "Diabetic retinopathy ": 2.8563304883267358, "Diarrhoea haemorrhagic ": 3.1154892761955524, "Dislocation of vertebra ": 9.009683414896852, "Drug resistance ": 6.877050539761385, "Drug specific antibody present ": 10.871088511389091, "Drug tolerance decreased ": 8.440006691825143, "Drug-induced liver injury ": 2.005009463564893, "Dysbiosis ": 9.295240045622233, "Dyslipidaemia ": 9.76149781482696, "Dyspepsia ": 5.575246308052946, "Dyspnoea at rest ": 5.174267971881172, "Electrocardiogram QT prolonged ": 20.009553539409172, "Electrolyte depletion ": 34.006751629964945, "Electrolyte imbalance ": 6.448536023567732, "Endometriosis ": 3.562227234659592, "Enterocolitis ": 3.209273320618893, "Erythema ": 3.328677677800568, "Female genital tract fistula ": 169.4551418725758, "Frequent bowel movements ": 65.57882864305256, "Gastritis ": 3.522877254108869, "Gastroenteritis ": 6.3774856230606485, "Grip strength ": 278.6191839434603, "HIV infection ": 21.48713133078371, "Haematochezia ": 19.042815628925773, "Haemoglobin decreased ": 2.714781668803715, "Haemoptysis ": 2.647837925592657, "Hepatic cirrhosis ": 2.646538969577636, "Hepatitis ": 3.4421082558839657, "Hepatitis A ": 9.863488948402903, "Hepatomegaly ": 2.5190760484170025, "Herbal toxicity ": 492.1708209018281, "Hypoalbuminaemia ": 11.426984510850284, "Hypocalcaemia ": 9.439833480371767, "Hypokalaemia ": 4.100992357832779, "Hypomagnesaemia ": 13.267905181399106, "Hypothyroidism ": 2.7019249988418075, "Hypovolaemic shock ": 3.476290496637614, "Immobile ": 4.614953050810559, "Impaired quality of life ": 2.987953025820135, "Incorrect product administration duration ": 20.628353497619106, "Inflammatory bowel disease ": 10.577831970737904, "Infusion related reaction ": 9.85698474658934, "Intentional product use issue ": 5.107189440060783, "Iron deficiency anaemia ": 3.7543248014955513, "Laboratory test abnormal ": 2.227604997213776, "Left ventricular hypertrophy ": 2.828867267371061, "Lip dry ": 3.288616115737017, "Lower limb fracture ": 3.048400734091228, "Lung disorder ": 2.213670110821123, "Lupus vulgaris ": 80.78693278955653, "Lupus-like syndrome ": 8.808402035961873, "Macular degeneration ": 52.69591190606454, "Malnutrition ": 2.553992999526739, "Meningitis ": 3.650332361743743, "Meningitis bacterial ": 12.982161620973324, "Meningitis tuberculous ": 75.855969798588, "Mucous stools ": 4.805222502931265, "Multiple-drug resistance ": 3.427056268840273, "Muscle contractions involuntary ": 2.82479437504366, "Muscle injury ": 3.260409262178809, "Mycobacterium test positive ": 46.7131363565164, "Myocardial ischaemia ": 2.2842172773270764, "Nephritis ": 5.984178775828358, "Neuropathy peripheral ": 5.4214982400282405, "Obesity ": 2.858997403932905, "Oesophageal candidiasis ": 3.2860666445853672, "Off label use ": 2.9539539445469054, "Optic neuritis ": 7.993482644255071, "Oral candidiasis ": 62.15940815585522, "Ototoxicity ": 22.31138591229001, "Pancreatitis chronic ": 8.890763123775479, "Papilloedema ": 3.65535516676802, "Paraesthesia oral ": 24.09811691262469, "Pathogen resistance ": 3.1236267533958357, "Peripheral artery occlusion ": 7.063615947994778, "Peripheral sensorimotor neuropathy ": 14.16113331860664, "Peripheral sensory neuropathy ": 2.826441540427532, "Platelet count increased ": 6.496394947453721, "Pneumonectomy ": 49.00196345517049, "Pneumothorax ": 3.414693284495831, "Pneumothorax spontaneous ": 20.207553212424017, "Pregnancy ": 4.032461398331105, "Prescribed underdose ": 3.1467426373590417, "Procedural pain ": 39.64681039436218, "Proctitis ": 146.21761997883382, "Psychotic disorder ": 3.278958317852486, "Pulmonary tuberculosis ": 37.58363606480747, "Purulent discharge ": 17.430934757856942, "Radiculopathy ": 123.76427984701807, "Rectal discharge ": 21.2759915879959, "Rectal haemorrhage ": 20.57362400976395, "Red blood cell count decreased ": 2.3403199476624468, "Refraction disorder ": 46.7131363565164, "Respiratory failure ": 7.279521893177401, "Rheumatic fever ": 5.271767300810192, "Seronegative arthritis ": 30.847126119186527, "Skin warm ": 4.33072139927645, "Sleep disorder due to a general medical condition ": 2.0674883309448844, "Spinal fusion surgery ": 19.360580322737803, "Spondylitis ": 16.471506387492404, "Sputum culture positive ": 46.333141196941135, "Subcutaneous abscess ": 11.514146684966835, "Therapeutic product effect incomplete ": 12.73320183819205, "Toxic optic neuropathy ": 71.25247674281823, "Treatment failure ": 2.7115410232339574, "Treatment noncompliance ": 2.521055693229441, "Tuberculoma of central nervous system ": 42.360349954131486, "Tuberculosis ": 30.57288789121698, "Uraemic encephalopathy ": 154.98763315654847, "Vaginal discharge ": 87.03466527243312, "Vaginal flatulence ": 206.98563694845055, "Ventricular extrasystoles ": 5.159829738245159, "Weight decreased ": 5.490725383114952, "White blood cell count increased ": 4.48143174191488}
\ No newline at end of file
+{"Abscess": 7.868278144604589, "Abscess limb": 23.63360683482409, "Acinetobacter infection": 95.3788230832942, "Acoustic neuroma": 89.69608075187472, "Acute generalised exanthematous pustulosis": 5.658988385009125, "Acute kidney injury": 4.214671752057169, "Alanine aminotransferase increased": 2.8693614475672438, "Anticoagulation drug level above therapeutic": 38.4740518413227, "Anuria": 4.178088750542549, "Anxiety disorder": 9.656380191759064, "Aspergillus infection": 18.113661635648967, "Ataxia": 2.071857426826283, "Atypical mycobacterial infection": 45.750479287930375, "Atypical mycobacterium test positive": 534.8625835358554, "Bacterial infection": 4.606451117559942, "Blood albumin decreased": 6.092170882102, "Brain abscess": 26.55995398593603, "Bronchiectasis": 10.289576518451682, "Bronchopulmonary aspergillosis": 6.186924017394556, "Cachexia": 9.841647946733753, "Candida infection": 19.01015777720368, "Cheilitis": 8.653335205272196, "Clostridium difficile colitis": 19.65318733007692, "Clostridium difficile infection": 4.058652063326903, "Condition aggravated": 3.7208174939073615, "Congenital aplasia": 28.472236580355805, "Cytomegalovirus infection": 2.975346064102555, "Cytopenia": 3.5828262500426264, "Deafness": 20.19182224680455, "Deafness bilateral": 28.48454022944031, "Deafness neurosensory": 49.65664319903518, "Depressive symptom": 9.404026951051693, "Dermatitis": 2.127293656113573, "Dermatitis exfoliative generalised": 5.746425597486221, "Disease recurrence": 6.960585413412245, "Disseminated mycobacterium avium complex infection": 179.9172786839936, "Drug ineffective": 3.257039201395416, "Drug ineffective for unapproved indication": 7.270823552460221, "Drug intolerance": 3.8688369079297513, "Drug reaction with eosinophilia and systemic symptoms": 19.398358083179648, "Drug resistance": 31.621807338038334, "Drug-induced liver injury": 3.2941230423054217, "Dysaesthesia": 3.7800801003837576, "Electrocardiogram QT prolonged": 7.218605522408021, "Electrolyte imbalance": 6.020200806806434, "Encephalopathy": 2.0985831552579417, "Enterococcal infection": 79.11836155207891, "Eosinophilia": 9.349164823905468, "Escherichia infection": 11.186862530832292, "Escherichia sepsis": 31.99014606105109, "Escherichia urinary tract infection": 16.734222936633564, "Febrile neutropenia": 2.0624746107322904, "Fungaemia": 73.55685619394276, "Gamma-glutamyltransferase increased": 3.0065535079785235, "Gastrointestinal disorder": 2.2058439510060857, "Haematocrit decreased": 3.892416527627805, "Haemodynamic instability": 13.72693929803472, "Haemoptysis": 2.5768331030786094, "Hepatic cytolysis": 7.032462262712173, "Hepatic enzyme increased": 3.0312665364121374, "Hepatic function abnormal": 2.051119123426317, "Hepatitis": 2.231844898558922, "Hepatotoxicity": 5.232923293963265, "Hyperbilirubinaemia": 4.180003636970371, "Hyperlactacidaemia": 15.303986672376556, "Hypoacusis": 5.561955307910981, "Hypoalbuminaemia": 6.738321961176094, "Hypogammaglobulinaemia": 13.352707042156537, "Hypomagnesaemia": 4.913407135136728, "Hypoproteinaemia": 26.12155459479332, "Hypoxia": 4.797577679130017, "Immune reconstitution inflammatory syndrome": 6.272124571394586, "Inflammatory marker increased": 14.389638833673551, "Intentional product use issue": 3.1424090786547647, "Klebsiella infection": 95.87163851363572, "Leukocytosis": 3.0157308620725773, "Leukopenia": 2.6576950295137056, "Liver abscess": 15.503320153638995, "Lung transplant rejection": 86.75445446744452, "Lymphadenitis": 2.9665863224673688, "Lymphopenia": 3.1734161064888395, "Metabolic acidosis": 3.01167565933921, "Microangiopathic haemolytic anaemia": 70.77640694401363, "Moraxella infection": 234.4438383409893, "Mucormycosis": 25.668700284221813, "Multiple organ dysfunction syndrome": 7.609418994484369, "Multiple-drug resistance": 9.484347282901172, "Mycobacterial infection": 51.05499789923144, "Mycobacterium abscessus infection": 644.3524522687882, "Mycobacterium avium complex infection": 208.6702244361007, "Neonatal candida infection": 1321.3792121936094, "Nephropathy toxic": 18.60198113024841, "Neuropathy peripheral": 2.560224146769581, "Nodule": 4.606356276354017, "Off label use": 2.24111715502466, "Oliguria": 4.12182206682986, "Optic neuritis": 8.628884490105358, "Otitis media": 9.069150587417631, "Ototoxicity": 275.40436637700014, "Pancytopenia": 2.3218026713617226, "Pathogen resistance": 47.53185946752846, "Pleurisy": 6.735529907934369, "Polyp": 8.723592742098521, "Product prescribing error": 4.222294779045326, "Product use in unapproved indication": 3.434444910283996, "Proteus infection": 120.9803622922906, "Pseudomembranous colitis": 6.97841915403745, "Pseudomonas infection": 22.172232147919782, "Pulmonary cavitation": 49.7260167254742, "Pulmonary haemorrhage": 11.089191250638232, "Pulmonary mass": 5.923889203078185, "Pyelonephritis": 4.239618964789491, "Rash erythematous": 2.219900181749688, "Rash maculo-papular": 8.859653169574724, "Rash morbilliform": 2.793935905518331, "Red blood cell sedimentation rate increased": 3.918920902624868, "Renal impairment": 2.0960871129045366, "Renal tubular necrosis": 3.884189364934071, "Respiratory distress": 3.08836736286121, "Respiratory failure": 3.2289665668490297, "Sepsis": 3.3722477685664174, "Septic shock": 8.943578777579065, "Shock": 4.433847037674333, "Skin lesion": 3.640030679547249, "Staphylococcal infection": 3.1385542133827, "Staphylococcal sepsis": 9.81378396551248, "Stevens-Johnson syndrome": 3.107716393098529, "Streptococcal infection": 17.30427004045918, "Systemic candida": 44.04506161520125, "Therapy non-responder": 3.188390642190167, "Thrombocytopenia": 3.2520452180725217, "Tinnitus": 2.754651579354128, "Toxic epidermal necrolysis": 2.5171902050598183, "Transaminases increased": 3.1885093755730485, "Transplant rejection": 11.040073635175988, "Treatment failure": 5.479122433260497, "Tuberculosis": 10.360097953491495}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/680.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/680.json
index 70bb32548df..22065d69726 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/680.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/680.json
@@ -1 +1 @@
-{"Dizziness ": 2.903327044432503, "Hypersensitivity ": 10.491812645552178}
\ No newline at end of file
+{"Abdominal distension": 2.029979046351197, "Alopecia": 2.278752816790884, "Anaemia": 7.917730241563449, "Ascites": 6.352302478703547, "Bacteraemia": 3.005459280679409, "Biliary obstruction": 31.98337498721818, "Blood bilirubin increased": 2.6460735743371093, "Blood potassium decreased": 2.0863835900605374, "Cancer pain": 22.77968776464956, "Carbohydrate antigen 19-9 increased": 42.57335920705888, "Carcinoembryonic antigen increased": 42.55156315410201, "Chromaturia": 4.276619544596277, "Colon cancer": 7.129126715469529, "Colon cancer metastatic": 27.655400712636325, "Colorectal cancer metastatic": 31.77209285306245, "Constipation": 3.0480924006547734, "Cytopenia": 13.801014738541324, "Death": 11.340613591005068, "Decreased appetite": 4.048031481231627, "Dehydration": 4.588422950296485, "Diarrhoea": 3.0750771821074565, "Disease progression": 33.53438385997516, "Dysphonia": 2.201331234690422, "Febrile neutropenia": 9.407784526088236, "Feeding disorder": 2.7428534297056557, "Full blood count abnormal": 6.023692379471247, "Gastrointestinal toxicity": 8.75236664587835, "General physical health deterioration": 2.427989080984312, "Haematotoxicity": 7.130697356303676, "Haemoglobin decreased": 3.645895770628058, "Hepatic failure": 3.0403359611977687, "Hospitalisation": 7.42618719347173, "Hydronephrosis": 5.704149244143079, "Hyperbilirubinaemia": 2.556312633099909, "Hypophagia": 2.41741965171428, "Inappropriate schedule of product administration": 8.573613017843925, "Intentional product use issue": 6.709232006755912, "Intercepted product prescribing error": 50.29835026126475, "Intestinal obstruction": 9.856655872826012, "Intra-abdominal fluid collection": 22.33568371094168, "Jaundice": 2.7572258199978266, "Large intestinal obstruction": 35.05839673789991, "Leukocytosis": 2.549562938245106, "Leukopenia": 7.581967040813956, "Malignant neoplasm progression": 5.398532703412329, "Metastases to central nervous system": 2.7283763054667407, "Metastases to liver": 2.0058006572712084, "Metastases to lung": 2.995133353364316, "Nausea": 2.0181592721746093, "Neutropenia": 17.473904428080207, "Neutrophil count decreased": 4.345476928298887, "No adverse event": 2.6711274281813404, "Onychoclasis": 13.521904378026498, "Palmar-plantar erythrodysaesthesia syndrome": 2.95466344205187, "Pancytopenia": 4.316328080531182, "Performance status decreased": 11.054507460595712, "Platelet count decreased": 3.300458465927376, "Prescribed underdose": 12.061890520799398, "Product availability issue": 42.75693475670063, "Product prescribing error": 2.4059803976167813, "Product use issue": 3.912583577097015, "Red blood cell count decreased": 8.974819528740571, "Septic shock": 2.000584116995454, "Small intestinal obstruction": 13.558433677410653, "Surgery": 2.298846964427156, "Taste disorder": 2.652450755374248, "Terminal state": 8.481058799994022, "Thrombocytopenia": 4.576879357992028, "Transfusion": 11.417484940528787, "Umbilical hernia": 13.986086143251596, "Urinary tract infection": 3.0301102318131417, "Vomiting": 2.332944022020765, "Weight decreased": 3.198387762034814, "White blood cell count decreased": 6.711295721444728}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/681.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/681.json
index 36145bfc0f5..61edd00895a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/681.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/681.json
@@ -1 +1 @@
-{"Adverse drug reaction ": 15.624488438250165, "Alanine aminotransferase increased ": 4.91060464575573, "Aspartate aminotransferase increased ": 5.613064780348587, "Cholestasis ": 18.831227719531736, "Diarrhoea ": 7.907430577262925, "Disease progression ": 128.2050592903027, "Hepatic cytolysis ": 58.380440353621815, "Hepatic enzyme increased ": 7.465820312607308, "Hepatotoxicity ": 50.388295503148655, "Lung adenocarcinoma ": 247.78417504984668, "Non-small cell lung cancer ": 262.62199792081105, "Off label use ": 3.1660013465774504}
\ No newline at end of file
+{"Acute hepatic failure": 7.007636297572402, "Acute kidney injury": 3.6693926240581023, "Adrenal insufficiency": 7.029707143190917, "Adrenal suppression": 157.6351853153346, "Adverse event": 2.034811110146828, "Atrial flutter": 11.8896622408151, "Blood alkaline phosphatase increased": 2.6069441182306283, "COVID-19 pneumonia": 7.5465038571801, "Candida infection": 12.92411965409401, "Condition aggravated": 2.155361663824539, "Cortisol decreased": 64.3585504574103, "Cushing's syndrome": 105.97640135108598, "Cushingoid": 69.2044289190311, "Diarrhoea": 3.4180807820762387, "Drug effective for unapproved indication": 23.32659153443981, "Drug ineffective for unapproved indication": 10.835440783028282, "Drug interaction": 19.143653200222683, "Drug level increased": 24.87956277607421, "Drug resistance": 4.377913627622504, "Drug-induced liver injury": 2.85918259726783, "Dyslipidaemia": 78.29968435779139, "Electrocardiogram QT prolonged": 19.611447220983536, "Eosinophilia": 5.207396936186621, "Ergot poisoning": 982.4939344662204, "Fanconi syndrome": 58.44085990009605, "Fanconi syndrome acquired": 39.72143185987597, "Foetal exposure during pregnancy": 4.4603940342105, "Glycosuria": 35.848356057355105, "Haematotoxicity": 16.997252055293124, "Hepatotoxicity": 9.612157118370458, "Hypertransaminasaemia": 8.076201285937115, "Hypertriglyceridaemia": 11.904320162033985, "Hypophosphataemia": 18.21857133765413, "Immune reconstitution inflammatory syndrome": 26.93665728607972, "Live birth": 20.221478650607683, "Liver injury": 5.150873041398871, "Maternal exposure during pregnancy": 4.377107597618974, "Metabolic acidosis": 4.7148065446160246, "Nephropathy toxic": 8.724465001595059, "Off label use": 10.510523247296232, "Osteomalacia": 18.693486370555608, "Osteonecrosis": 2.048832851484157, "Osteopenia": 2.5937450672109112, "Peripheral coldness": 6.468816713693809, "Peripheral pulse decreased": 466.2048133717102, "Pre-existing condition improved": 295.22224298423896, "Premature delivery": 7.949720235856247, "Proteinuria": 3.821691489808856, "Rash maculo-papular": 5.377962428656929, "Rash pruritic": 2.5075668717309654, "Renal tubular acidosis": 43.550412656620615, "Renal tubular necrosis": 11.673616049739843, "Respiratory failure": 2.28957457415554, "Rhabdomyolysis": 3.1197316057459457, "Sinus bradycardia": 9.876686050719332, "Skin striae": 102.90567499587092, "Stress fracture": 37.802660426631626, "Supraventricular tachycardia": 7.424767570175218, "Therapeutic product effect incomplete": 3.597620265628212, "Therapeutic response unexpected": 36.98027181065961, "Virologic failure": 20.18505914278913, "Weight increased": 2.6745528371771834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/682.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/682.json
index 7407a868556..8de9bba6b5b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/682.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/682.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.7249268134251623, "Abdominal pain upper ": 2.3201922779563326, "Acute kidney injury ": 2.3251902215106406, "Alopecia ": 2.1662788086983205, "Blood creatinine increased ": 11.126481027574018, "Blood pressure increased ": 2.42346314653226, "Dehydration ": 3.1530063542706386, "Glomerular filtration rate decreased ": 54.10652661597313, "Hyperkalaemia ": 3.2292311509411893, "Hypertension ": 11.374951146910236, "Joint swelling ": 2.491234741061107, "Lupus nephritis ": 155.4193937872188, "Memory impairment ": 2.151472970190159, "Oedema ": 3.124616948541081, "Product dose omission issue ": 5.418544172281393, "Proteinuria ": 45.94678797603984, "Renal impairment ": 4.386016831111509, "Systemic lupus erythematosus ": 24.51061087989994, "Therapy interrupted ": 60.49324747626236, "Tremor ": 2.3838933776968827, "Urinary tract infection ": 3.1798811876177697, "Urine protein/creatinine ratio increased ": 2514.128171906478, "Weight decreased ": 2.04772593949959}
\ No newline at end of file
+{"Diarrhoea": 10.614923947236475, "Hepatic cytolysis": 122.11118204794056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/683.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/683.json
index 98945e4019f..4357937ac6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/683.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/683.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 15.157694377695112, "Affect lability ": 25.37238668375416, "Aggression ": 13.398758145226614, "Agitation ": 6.932777359124982, "Akathisia ": 38.58075478871739, "Anosognosia ": 275.6954898661859, "Completed suicide ": 25.219381301105365, "Condition aggravated ": 3.2758868914843324, "Delusion ": 35.31515533057852, "Depressed mood ": 5.137454208885906, "Drug ineffective for unapproved indication ": 40.96367447735837, "Extrapyramidal disorder ": 11.732415876037631, "Hallucination, auditory ": 35.75094149436588, "Hostility ": 134.50611419118653, "Hyperprolactinaemia ": 169.6362941259309, "Intentional product misuse ": 2.365366297291258, "Irritability ": 5.09276508583079, "Mania ": 26.33287787536992, "Medication error ": 14.313870110906905, "Myocarditis ": 5.952689749045105, "Neuroleptic malignant syndrome ": 20.48484485657965, "Off label use ": 4.156123352044497, "Overdose ": 3.9029597959734046, "Paradoxical drug reaction ": 98.99268137396714, "Persecutory delusion ": 86.42905429623825, "Persistent genital arousal disorder ": 4464.526009175805, "Psychotic disorder ": 8.879112032409159, "Psychotic symptom ": 221.79228294144903, "Schizophrenia ": 57.35541437371493, "Sedation ": 18.28555559926985, "Serotonin syndrome ": 34.98809190421349, "Sleep disorder ": 2.4417419319407294, "Suicidal ideation ": 7.637357998055891, "Tardive dyskinesia ": 32.6024874450853, "Therapeutic response decreased ": 7.96995221824886, "Toxicity to various agents ": 8.60669550186828, "Treatment noncompliance ": 13.187563734024057, "Weight increased ": 2.1472522977042146, "Withdrawal syndrome ": 16.10687412437745}
\ No newline at end of file
+{"Agitation": 4.017740379748436, "Altered state of consciousness": 7.47240532226129, "Cardiogenic shock": 25.85309436914321, "Coma": 8.690055686184495, "Completed suicide": 2.830872298326427, "Condition aggravated": 3.7307338277763296, "Death": 2.414109899985138, "Drug abuse": 15.312618666358835, "Drug ineffective": 2.412196519356093, "Drug interaction": 2.8926850481260464, "Drug resistance": 16.684796681170937, "Extrapyramidal disorder": 17.46911214507023, "Generalised tonic-clonic seizure": 14.50084368750199, "Hypocalcaemia": 28.709133522073564, "Hypoparathyroidism": 532.6009034077952, "Hypotension": 2.967594216507277, "Mental disorder": 9.37636320254358, "Muscle twitching": 12.193786743794403, "Myoclonus": 32.00133395568836, "Neuroleptic malignant syndrome": 22.794503539131547, "Overdose": 6.888201236158349, "Parkinsonism": 34.10754488140372, "Poisoning": 64.84474681924394, "Poisoning deliberate": 59.6502768504546, "Product use in unapproved indication": 2.804075252826336, "Pulmonary embolism": 2.5113314247839105, "Sedation": 14.53558252909778, "Seizure": 2.500874234896388, "Somnolence": 3.003346524884288, "Suicide attempt": 5.288660770896732, "Tardive dyskinesia": 54.984589144793546, "Toxicity to various agents": 6.251686584021923, "Treatment failure": 13.916666631202588, "Weight increased": 2.1533362830076164}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/684.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/684.json
index 6ca22b477c0..a58739581ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/684.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/684.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.4284638987535034, "Alopecia ": 3.0420841118096336, "Ascites ": 5.0770647999392216, "Carcinoid crisis ": 729.9988052503513, "Carcinoid syndrome ": 372.307967345474, "Disease progression ": 11.408197248332543, "Eating disorder ": 6.5331749117395095, "Faeces soft ": 27.946625081114437, "Flushing ": 8.427859626246216, "Gastroenteropancreatic neuroendocrine tumour disease ": 1591.4611163225388, "General physical health deterioration ": 7.790425950770851, "Haematotoxicity ": 30.436555517539382, "Hepatic failure ": 3.095572143425118, "Ill-defined disorder ": 70.3279944907816, "Illness ": 4.355454135335968, "Inappropriate schedule of product administration ": 3.8027043099293487, "Intentional product use issue ": 4.972946445322618, "Intestinal obstruction ": 11.951299568734497, "Jaundice ": 2.697811465500182, "Laboratory test abnormal ": 10.53113452785168, "Leukopenia ": 5.28041612760406, "Lymphopenia ": 30.395794333192743, "Malignant neoplasm progression ": 11.689206230877357, "Metastases to liver ": 17.84323881092934, "Myelodysplastic syndrome ": 18.3515893862464, "Neoplasm progression ": 6.787175024997808, "Neuroendocrine tumour ": 432.6586984026894, "Neutropenia ": 3.2039211020232017, "Oral herpes ": 6.461218656891535, "Pancreatic neuroendocrine tumour ": 167.3917756535081, "Pancytopenia ": 3.920631046771508, "Platelet count decreased ": 4.628617844610371, "Renal impairment ": 2.346583951436769, "Thrombocytopenia ": 13.773380242111056, "Weight decreased ": 2.060968086459456}
\ No newline at end of file
+{"Eye irritation": 27.923730388082124, "Eye pain": 17.82701144203305, "Vision blurred": 4.530590928327984, "Visual acuity reduced": 38.290648912713706, "Visual impairment": 5.673552456338943, "Vitreous floaters": 50.7839591065242}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/685.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/685.json
index 2b77aee8f25..6a25ff38ca8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/685.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/685.json
@@ -1 +1 @@
-{"Alopecia ": 3.763309598438707, "Anaemia ": 5.2412496160105055, "Blood pressure systolic increased ": 19.2508836720835, "Body temperature decreased ": 29.588294205029012, "Carcinoid crisis ": 1264.3536851062606, "Constipation ": 2.0435113117380914, "Disease progression ": 2.279656577696442, "Eating disorder ": 24.130595487623506, "Faeces soft ": 61.352075302252274, "Haematotoxicity ": 53.23100045612008, "Illness ": 2.773754497421828, "Injection site mass ": 24.14235755997068, "Leukopenia ": 7.012303433342856, "Malignant neoplasm progression ": 7.052373895510567, "Myelodysplastic syndrome ": 114.05385490438854, "Neoplasm progression ": 6.259368173684158, "Nephropathy toxic ": 17.83469840638457, "Product use in unapproved indication ": 3.069821070036525, "Therapy partial responder ": 29.74898920833145, "Thrombocytopenia ": 14.0808610297814, "Weight decreased ": 2.372011668793005}
\ No newline at end of file
+{"Drug interaction": 42.273599806397776, "Drug level decreased": 575.3483451786454}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/686.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/686.json
index 6adca5a825d..68a16c60a36 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/686.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/686.json
@@ -1 +1 @@
-{"Abdominal distension ": 72.30939874493079, "Abdominal pain ": 13.967377139578474, "Ovarian hyperstimulation syndrome ": 856.7378404412825}
\ No newline at end of file
+{"Corneal opacity": 533.1505615899403, "Fall": 5.402814161514618, "Intraocular pressure increased": 159.09026808163892}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/687.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/687.json
index f35554c3d43..a34f9ba22e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/687.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/687.json
@@ -1 +1 @@
-{"Abdominal distension ": 63.366491315461104, "Abdominal pain ": 13.562397155142616, "Abdominal pain lower ": 41.22377280101578, "Ascites ": 23.48742004773497, "Chest discomfort ": 6.0168872954927695, "Dyspnoea ": 2.584030096245786, "Nausea ": 2.0954448636457466, "Ovarian hyperstimulation syndrome ": 1783.289084149633, "Vomiting ": 2.964469747017076, "Waist circumference increased ": 1068.125355537261}
\ No newline at end of file
+{"Dizziness": 2.903306890150727, "Hypersensitivity": 10.491812645552178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/688.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/688.json
index 25986b2c839..88571a200bf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/688.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/688.json
@@ -1 +1 @@
-{"Blindness ": 29.528157804574704, "Intraocular pressure increased ": 429.7422670112431, "Photophobia ": 33.10168806744936, "Retinal degeneration ": 8002.012273288915, "Retinal deposits ": 9965.152892245856, "Retinal detachment ": 305.5062079943043, "Retinal tear ": 709.9379170442716, "Vision blurred ": 8.636445954402651, "Visual impairment ": 15.390855893424083}
\ No newline at end of file
+{"Adverse drug reaction": 15.624488438250165, "Alanine aminotransferase increased": 4.91060464575573, "Aspartate aminotransferase increased": 5.613064780348587, "Cholestasis": 18.831227719531736, "Diarrhoea": 7.907364570597084, "Disease progression": 128.2050592903027, "Hepatic cytolysis": 58.380440353621815, "Hepatic enzyme increased": 7.465820312607308, "Hepatotoxicity": 50.388295503148655, "Lung adenocarcinoma": 247.78417504984668, "Non-small cell lung cancer": 262.62199792081105, "Off label use": 3.1658766458915157}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/689.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/689.json
index 05ec263a419..645b886890d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/689.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/689.json
@@ -1 +1 @@
-{"Acute leukaemia ": 15.207844750106952, "Acute myeloid leukaemia ": 25.191849407431505, "Adverse drug reaction ": 2.217153309336953, "Anaemia ": 34.21014438528105, "Ascites ": 3.7112777515745257, "Blood creatinine increased ": 2.732543476246841, "Blood test abnormal ": 2.445219008354557, "Carbohydrate antigen 125 increased ": 312.667381915897, "Creatinine renal clearance decreased ": 2.839541595553669, "Decreased appetite ": 2.6437447171207533, "Disease progression ": 3.3461585891047227, "Disease recurrence ": 2.156441568350458, "Erythema nodosum ": 4.2322546697105485, "Feeding disorder ": 2.3689014331112577, "Full blood count abnormal ": 2.135613311109175, "Full blood count decreased ": 2.628132873229284, "Glomerular filtration rate decreased ": 3.351891295247144, "Haematotoxicity ": 20.231247227822493, "Haemoglobin decreased ": 8.042434918109775, "Ileus ": 14.340973853391326, "Interstitial lung disease ": 8.120211217308196, "Intestinal obstruction ": 4.635870524907283, "Laboratory test abnormal ": 2.688679409913006, "Leukaemia ": 7.248800798708685, "Leukopenia ": 2.4391107890161843, "Malignant neoplasm progression ": 21.829110716766078, "Metastases to bone ": 7.859001519196086, "Metastases to central nervous system ": 15.617552643685949, "Metastases to liver ": 6.367899244213283, "Metastases to lung ": 3.5095021094296475, "Metastases to lymph nodes ": 10.986428217050255, "Metastases to meninges ": 10.919971421604256, "Metastases to peritoneum ": 30.631896287468688, "Metastases to spine ": 10.11919456863008, "Metastasis ": 20.48839259768505, "Myelodysplastic syndrome ": 66.9554390594016, "Myelosuppression ": 4.744439594719571, "Nausea ": 2.780230261913804, "Neoplasm ": 5.275852587468256, "Neutropenia ": 3.690068859037317, "Neutrophil count decreased ": 16.13994611459273, "No adverse event ": 5.728751473358724, "Off label use ": 2.8971997885720517, "Ovarian cancer ": 13.922675841615671, "Ovarian cancer recurrent ": 856.9699592211797, "Pancytopenia ": 4.860710280438424, "Platelet count decreased ": 8.074799902599395, "Pneumocystis jirovecii pneumonia ": 3.963258387920126, "Pneumonitis ": 4.945725390177708, "Product dose omission issue ": 2.307515518669556, "Product use complaint ": 6.036027443364017, "Product use in unapproved indication ": 2.229474478421362, "Prostatic specific antigen increased ": 12.811893746207485, "Pulmonary toxicity ": 2.8325182373035886, "Recurrent cancer ": 34.705306466483904, "Red blood cell count decreased ": 5.516407801376233, "Renal impairment ": 2.874502390787614, "Stomatitis ": 2.2713300490759063, "Taste disorder ": 6.621062715260355, "Thrombocytopenia ": 4.646955866063744, "Tumour marker increased ": 48.00345852090853, "White blood cell count decreased ": 3.803987908531559}
\ No newline at end of file
+{"Abdominal discomfort": 2.7249268134251623, "Abdominal pain upper": 2.3201922779563326, "Acute kidney injury": 2.3251902215106406, "Alopecia": 2.1662788086983205, "Blood creatinine increased": 11.126481027574018, "Blood pressure increased": 2.423420612515477, "Dehydration": 3.1528380584418776, "Glomerular filtration rate decreased": 54.10652661597313, "Hyperkalaemia": 3.2287859875406157, "Hypertension": 11.374833627570595, "Joint swelling": 2.491234741061107, "Lupus nephritis": 155.4193937872188, "Memory impairment": 2.151472970190159, "Oedema": 3.124616948541081, "Product dose omission issue": 5.418544172281393, "Proteinuria": 45.94678797603984, "Renal impairment": 4.386016831111509, "Systemic lupus erythematosus": 24.51061087989994, "Therapy interrupted": 60.49324747626236, "Tremor": 2.38380332841298, "Urinary tract infection": 3.1798811876177697, "Urine protein/creatinine ratio increased": 2514.128171906478, "Weight decreased": 2.04772593949959}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/69.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/69.json
index e8080df8023..9e64f51c4aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/69.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/69.json
@@ -1 +1 @@
-{"Ventricular tachycardia ": 52.8856459910641}
\ No newline at end of file
+{"Abdominal pain": 3.3437141919860025, "Adjustment disorder with depressed mood": 32.407784685791746, "Adverse drug reaction": 6.645147571515391, "Adverse event": 4.685938319955347, "Alcohol poisoning": 5.001489980624515, "Amnesia": 3.808849611886302, "Anaemia": 7.750340702567592, "Anti-cyclic citrullinated peptide antibody positive": 5.830572715093489, "Arterial disorder": 7.441972642488024, "Arthritis": 2.52395774711242, "Arthropathy": 2.329512758318693, "Arthropod bite": 12.697509728922162, "Aspartate aminotransferase increased": 2.460328287989767, "Bicytopenia": 6.118621922607735, "Blister": 2.0876604707061373, "Blood albumin decreased": 12.896221370899845, "Blood calcium decreased": 15.655533377231198, "Blood cholesterol increased": 3.5520433046379, "Blood creatinine decreased": 10.297877025771236, "Blood magnesium decreased": 18.28801422372262, "Blood potassium decreased": 4.896853183101811, "Blood sodium decreased": 8.781584017184526, "Bone erosion": 4.016127326760983, "Breast cancer stage III": 27.97891107944217, "Bursitis": 6.197631907260624, "C-reactive protein abnormal": 7.442237717755549, "Cardiopulmonary failure": 6.054997755175523, "Chronic sinusitis": 100.3854824212843, "Colitis": 27.556620337887317, "Colitis ulcerative": 41.42627502497341, "Constipation": 6.48903639271728, "Contusion": 2.118331954108597, "Cor pulmonale": 11.711072825290394, "Deafness bilateral": 5.612989687967537, "Deafness neurosensory": 3.975890909407739, "Deep vein thrombosis postoperative": 5.136803969116341, "Delirium": 3.3374459652188064, "Dengue fever": 9.010566589529642, "Diabetic retinopathy": 2.8563304883267358, "Diarrhoea haemorrhagic": 3.1154892761955524, "Dislocation of vertebra": 9.009683414896852, "Drug resistance": 6.877050539761385, "Drug specific antibody present": 10.871088511389091, "Drug tolerance decreased": 8.440006691825143, "Drug-induced liver injury": 2.004887025603433, "Dysbiosis": 9.295240045622233, "Dyslipidaemia": 9.76149781482696, "Dyspepsia": 5.575246308052946, "Dyspnoea at rest": 5.174267971881172, "Electrocardiogram QT prolonged": 20.009553539409172, "Electrolyte depletion": 34.006751629964945, "Electrolyte imbalance": 6.448536023567732, "Endometriosis": 3.562227234659592, "Enterocolitis": 3.209273320618893, "Erythema": 3.328645003586926, "Female genital tract fistula": 169.4551418725758, "Frequent bowel movements": 65.57882864305256, "Gastritis": 3.522877254108869, "Gastroenteritis": 6.3774856230606485, "Grip strength": 278.6191839434603, "HIV infection": 21.48713133078371, "Haematochezia": 19.04089314447869, "Haemoglobin decreased": 2.714781668803715, "Haemoptysis": 2.647837925592657, "Hepatic cirrhosis": 2.646538969577636, "Hepatitis": 3.4421082558839657, "Hepatitis A": 9.863488948402903, "Hepatomegaly": 2.5190760484170025, "Herbal toxicity": 492.1708209018281, "Hypoalbuminaemia": 11.426984510850284, "Hypocalcaemia": 9.439833480371767, "Hypokalaemia": 4.100992357832779, "Hypomagnesaemia": 13.267905181399106, "Hypothyroidism": 2.7019249988418075, "Hypovolaemic shock": 3.476290496637614, "Immobile": 4.614953050810559, "Impaired quality of life": 2.986795202043897, "Incorrect product administration duration": 20.628353497619106, "Inflammatory bowel disease": 10.577831970737904, "Infusion related reaction": 9.85698474658934, "Intentional product use issue": 5.107189440060783, "Iron deficiency anaemia": 3.75298833953584, "Laboratory test abnormal": 2.227604997213776, "Left ventricular hypertrophy": 2.828867267371061, "Lip dry": 3.288616115737017, "Lower limb fracture": 3.048400734091228, "Lung disorder": 2.213670110821123, "Lupus vulgaris": 80.78693278955653, "Lupus-like syndrome": 8.808402035961873, "Macular degeneration": 52.69591190606454, "Malnutrition": 2.553992999526739, "Meningitis": 3.650332361743743, "Meningitis bacterial": 12.982161620973324, "Meningitis tuberculous": 75.855969798588, "Mucous stools": 4.805222502931265, "Multiple-drug resistance": 3.427056268840273, "Muscle contractions involuntary": 2.82479437504366, "Muscle injury": 3.260409262178809, "Mycobacterium test positive": 46.7131363565164, "Myocardial ischaemia": 2.2842172773270764, "Nephritis": 5.984178775828358, "Neuropathy peripheral": 5.421332685387593, "Obesity": 2.858997403932905, "Oesophageal candidiasis": 3.2860666445853672, "Off label use": 2.9538372292703023, "Optic neuritis": 7.993482644255071, "Oral candidiasis": 62.15940815585522, "Ototoxicity": 22.31138591229001, "Pancreatitis chronic": 8.890763123775479, "Papilloedema": 3.65535516676802, "Paraesthesia oral": 24.09811691262469, "Pathogen resistance": 3.1236267533958357, "Peripheral artery occlusion": 7.063615947994778, "Peripheral sensorimotor neuropathy": 14.16113331860664, "Peripheral sensory neuropathy": 2.826441540427532, "Platelet count increased": 6.496394947453721, "Pneumonectomy": 49.00196345517049, "Pneumothorax": 3.414693284495831, "Pneumothorax spontaneous": 20.207553212424017, "Pregnancy": 4.032461398331105, "Prescribed underdose": 3.1467426373590417, "Procedural pain": 39.64681039436218, "Proctitis": 146.21761997883382, "Psychotic disorder": 3.278958317852486, "Pulmonary tuberculosis": 37.58363606480747, "Purulent discharge": 17.430934757856942, "Radiculopathy": 123.76427984701807, "Rectal discharge": 21.2759915879959, "Rectal haemorrhage": 20.57362400976395, "Red blood cell count decreased": 2.3403199476624468, "Refraction disorder": 46.7131363565164, "Respiratory failure": 7.278916083457141, "Rheumatic fever": 5.271767300810192, "Seronegative arthritis": 30.847126119186527, "Skin warm": 4.33072139927645, "Sleep disorder due to a general medical condition": 2.0674883309448844, "Spinal fusion surgery": 19.360580322737803, "Spondylitis": 16.471506387492404, "Sputum culture positive": 46.333141196941135, "Subcutaneous abscess": 11.514146684966835, "Therapeutic product effect incomplete": 12.73320183819205, "Toxic optic neuropathy": 71.25247674281823, "Treatment failure": 2.7115410232339574, "Treatment noncompliance": 2.521055693229441, "Tuberculoma of central nervous system": 42.360349954131486, "Tuberculosis": 30.57288789121698, "Uraemic encephalopathy": 154.98763315654847, "Vaginal discharge": 87.03466527243312, "Vaginal flatulence": 206.98563694845055, "Ventricular extrasystoles": 5.159829738245159, "Weight decreased": 5.490725383114952, "White blood cell count increased": 4.480569499568634}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/690.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/690.json
index 832987219b9..acb81a8d409 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/690.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/690.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 2.304746112151262, "Accident at work ": 7.896435367570602, "Aggression ": 2.502536961681152, "Agitation ": 2.1496008369226582, "Altered state of consciousness ": 3.5281681128856146, "Amnesia ": 3.2790992933892125, "Aneurysm ": 2.050321555741438, "Anger ": 2.8832334185879467, "Ankle fracture ": 2.265033883015292, "Ataxia ": 3.2096131492473, "Back disorder ": 10.10560767904088, "Back injury ": 3.898304783899627, "Balance disorder ": 2.380580131187978, "Bedridden ": 2.2220456618092865, "Behaviour disorder ": 2.403006636835625, "Bipolar disorder ": 2.1188013758066866, "Bladder disorder ": 2.59103728976664, "Blood disorder ": 2.31766545575503, "Blood pressure abnormal ": 3.5289564209797137, "Blood sodium decreased ": 2.1162756922365715, "Blood testosterone decreased ": 3.075390502789265, "Body height decreased ": 6.772166780721491, "Bradyphrenia ": 2.300529457551669, "Bradypnoea ": 4.252488055549134, "Brain injury ": 2.334075920073229, "Breakthrough pain ": 16.527429711624404, "Burning sensation ": 2.315685954320647, "Central nervous system lesion ": 2.038977404706756, "Cerebral disorder ": 2.760922985114899, "Cholestasis ": 2.4181646762087343, "Chronic obstructive pulmonary disease ": 2.2559603281490035, "Coma ": 4.782693282333893, "Complex regional pain syndrome ": 4.575283880701349, "Concussion ": 4.258872841361994, "Confusional state ": 3.559795804869992, "Craniocerebral injury ": 4.4351455254234535, "Crepitations ": 4.740154123889821, "Delirium ": 2.455470815238499, "Delusion ": 2.0981410098091517, "Dementia ": 2.385931706722768, "Depressed level of consciousness ": 3.1514821741942813, "Depression ": 2.419153073669097, "Diabetes mellitus ": 2.8729574806089, "Diabetic neuropathy ": 7.810944812397135, "Diplopia ": 3.0519599311044723, "Disorientation ": 3.125634777944516, "Disturbance in attention ": 2.1569181712155, "Dizziness exertional ": 9.743700679808548, "Drug abuse ": 4.529409275825149, "Drug abuser ": 4.990519418258603, "Drug dependence ": 4.188824040832167, "Drug diversion ": 5.609046106753419, "Drug hypersensitivity ": 2.089346387331452, "Drug ineffective for unapproved indication ": 3.078971119056433, "Drug interaction ": 2.8713494215292448, "Drug tolerance ": 2.2256111908488414, "Drug use disorder ": 4.70881465251169, "Drug withdrawal syndrome ": 2.1023597021723988, "Dry mouth ": 2.2889833656985075, "Dysarthria ": 2.7879703718715305, "Dyskinesia ": 2.511753916043684, "Dysphemia ": 3.003205078725949, "Dysstasia ": 2.3210063504680405, "Emotional disorder ": 2.1821146092635977, "Endometriosis ": 3.907113484818408, "Essential hypertension ": 3.2396025555340757, "Euphoric mood ": 5.30931359943844, "Exostosis ": 2.441806255464072, "Eye contusion ": 10.759858698931872, "Fall ": 3.8967362395573866, "Fear ": 2.716167522723849, "Feeling abnormal ": 3.7713802151917264, "Feeling drunk ": 6.431967538926984, "Fibromyalgia ": 6.984072770589046, "Fluid retention ": 2.0908405856265952, "Foot fracture ": 2.2617666870674014, "Gait disturbance ": 2.994555795534975, "Gait inability ": 2.677998695615264, "Gastrointestinal sounds abnormal ": 2.822372060384305, "Generalised anxiety disorder ": 5.57112066664281, "Hallucination ": 3.016653610318668, "Hallucination, visual ": 3.1899930063484985, "Hallucinations, mixed ": 2.994477298127325, "Head injury ": 2.988036728157918, "Hepatic cytolysis ": 3.411137044179161, "Hernia ": 5.406900300801098, "Hyperlipidaemia ": 2.6633295416151253, "Hypersomnia ": 2.224067639801236, "Hyporeflexia ": 2.718293052472552, "Illness ": 2.3341780381653754, "Impaired driving ability ": 9.84199815922839, "Increased appetite ": 2.715201198991129, "Infective exacerbation of chronic obstructive airways disease ": 26.167542330768477, "Intentional overdose ": 3.5011089666020343, "Intentional product misuse ": 4.146299536315696, "Intentional self-injury ": 3.4504393299099734, "Intervertebral disc degeneration ": 3.2879976125788755, "Intervertebral disc disorder ": 4.947066718841611, "Intervertebral disc protrusion ": 9.016357387725412, "Joint injury ": 2.096177884898779, "Ligament sprain ": 3.9034106916524753, "Lip erosion ": 7.2775840105700675, "Logorrhoea ": 2.781017828846475, "Loss of consciousness ": 2.09433026303426, "Loss of control of legs ": 6.752290098792746, "Lower limb fracture ": 2.794071534996463, "Memory impairment ": 4.22556505262172, "Mental impairment ": 2.8887378366452383, "Miosis ": 4.55360670432247, "Multiple sclerosis ": 2.5907315242993483, "Muscle contractions involuntary ": 2.3446628700076526, "Muscle disorder ": 4.392064065688369, "Muscle spasticity ": 4.902497859162001, "Mydriasis ": 2.413459283160653, "Myoclonus ": 6.473267967465594, "Near death experience ": 4.790857304035077, "Neck injury ": 7.539359501776247, "Nerve compression ": 4.999192310263951, "Nerve injury ": 8.55941714440394, "Nervousness ": 2.462824445142416, "Neuralgia ": 4.447744116238967, "Neuropathy peripheral ": 2.646881476557062, "Obesity ": 2.047583306796765, "Oedema peripheral ": 2.1250600396045454, "Oral mucosa erosion ": 4.395163592624496, "Overdose ": 2.261127925185482, "Overweight ": 2.7245223451990213, "Panic attack ": 2.8579206817138045, "Partial seizures ": 2.0611289854331467, "Peroneal nerve palsy ": 3.0366675408993498, "Persecutory delusion ": 3.333550984218779, "Pneumonia aspiration ": 3.275018423536069, "Poisoning ": 3.0837628093296803, "Poisoning deliberate ": 4.087179183234894, "Post herpetic neuralgia ": 6.390019563471146, "Post-traumatic stress disorder ": 4.852012383894664, "Potentiating drug interaction ": 5.170883876378313, "Pre-existing condition improved ": 7.160520774727868, "Prescription drug used without a prescription ": 2.698008873189033, "Psychomotor hyperactivity ": 2.1981642587290597, "Pulmonary thrombosis ": 3.141320055436205, "Pulmonary vascular resistance abnormality ": 189.433727430944, "Raynaud's phenomenon ": 2.0596882465307185, "Respiratory depression ": 3.5042459945546325, "Respiratory rate decreased ": 9.05834803322403, "Rhabdomyolysis ": 2.883749696193728, "Road traffic accident ": 6.22930393514226, "Sciatica ": 2.7674731205533214, "Sedation ": 3.2081484307212422, "Sensory loss ": 2.7508140847018545, "Sinus disorder ": 2.117530144028384, "Sjogren's syndrome ": 2.8975300755347253, "Sleep apnoea syndrome ": 3.2712674102035946, "Small intestinal obstruction ": 2.5140323324628544, "Social avoidant behaviour ": 2.2284792188845395, "Somnambulism ": 3.3853701653873003, "Somnolence ": 4.276325181778902, "Sopor ": 5.673833173102482, "Speech disorder ": 3.746990753168942, "Spinal column injury ": 6.659320175476379, "Spinal disorder ": 12.688716992478335, "Spinal fracture ": 2.605942913916511, "Spinal fusion surgery ": 4.60852882996694, "Spinal operation ": 3.125322458117241, "Spinal stenosis ": 3.167852980412283, "Substance use disorder ": 3.1043065071430163, "Sudden onset of sleep ": 5.416030893573151, "Suicidal ideation ": 2.792754734403592, "Suicide attempt ": 3.544014270839005, "Thinking abnormal ": 6.12180895640913, "Thyroid function test abnormal ": 5.148057677538167, "Toxic encephalopathy ": 2.218905308518178, "Type 2 diabetes mellitus ": 2.123096234314381, "Underdose ": 2.644347220793812, "Upper limb fracture ": 2.950091569427575, "Urinary incontinence ": 2.4252676051722104, "Urinary retention ": 3.242682768891989, "Urine abnormality ": 3.162055417140008, "Vision blurred ": 2.458921802057494, "Vitamin B12 deficiency ": 3.3800254127095326, "Vitamin D decreased ": 3.0119838845911846, "Weight increased ": 5.088366398311565, "Weight loss poor ": 3.929569603194068, "Withdrawal syndrome ": 7.04597262515944, "Wrong patient received product ": 4.618120617291731}
\ No newline at end of file
+{"Abnormal behaviour": 15.157694377695112, "Affect lability": 25.37238668375416, "Aggression": 13.398758145226614, "Agitation": 6.932777359124982, "Akathisia": 38.58075478871739, "Anosognosia": 275.6954898661859, "Completed suicide": 25.219381301105365, "Condition aggravated": 3.2758868914843324, "Delusion": 35.31515533057852, "Depressed mood": 5.137454208885906, "Drug ineffective for unapproved indication": 40.96367447735837, "Extrapyramidal disorder": 11.732415876037631, "Hallucination, auditory": 35.75094149436588, "Hostility": 134.50611419118653, "Hyperprolactinaemia": 169.6362941259309, "Intentional product misuse": 2.365366297291258, "Irritability": 5.092521876100791, "Mania": 26.33287787536992, "Medication error": 14.31284217940392, "Myocarditis": 5.952689749045105, "Neuroleptic malignant syndrome": 20.48484485657965, "Off label use": 4.155959613539818, "Overdose": 3.9029597959734046, "Paradoxical drug reaction": 98.99268137396714, "Persecutory delusion": 86.42905429623825, "Persistent genital arousal disorder": 4464.526009175805, "Psychotic disorder": 8.879112032409159, "Psychotic symptom": 221.79228294144903, "Schizophrenia": 57.35541437371493, "Sedation": 18.28555559926985, "Serotonin syndrome": 34.98809190421349, "Sleep disorder": 2.4417419319407294, "Suicidal ideation": 7.637357998055891, "Tardive dyskinesia": 32.6024874450853, "Therapeutic response decreased": 7.96995221824886, "Toxicity to various agents": 8.60669550186828, "Treatment noncompliance": 13.187563734024057, "Weight increased": 2.1472522977042146, "Withdrawal syndrome": 16.10687412437745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/691.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/691.json
index c02db439bc2..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/691.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/691.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 44.281390988049765, "Asthenia ": 2.088182812765148, "Decreased appetite ": 2.039283141278161, "Disturbance in attention ": 5.628209468934589, "Gamma-glutamyltransferase increased ": 12.242512024210331, "General physical health deterioration ": 4.466366245119725, "Hepatic enzyme increased ": 5.57478748706496, "Hypokalaemia ": 3.327568512886822, "Hypothyroidism ": 7.792186168294314, "Malignant neoplasm progression ": 7.1671120220053, "Memory impairment ": 3.0518598258782337, "Off label use ": 2.104002939154881, "Somnolence ": 3.620144475900979, "Vertigo ": 2.235873749672955, "Vomiting ": 2.237848237231778, "Weight decreased ": 3.508755933564427}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/692.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/692.json
index 76ba06a5e62..fb4675f20cb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/692.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/692.json
@@ -1 +1 @@
-{"Blood glucose abnormal ": 35.67015555704494, "Blood glucose decreased ": 12.020110699608816, "Blood glucose fluctuation ": 29.7734680108193, "Blood glucose increased ": 29.78010194026098, "Drug ineffective ": 2.26426645160208, "Expired product administered ": 15.131490389792624, "Glycosylated haemoglobin increased ": 23.480798525429787, "Hyperglycaemia ": 16.941635120085436, "Hypoglycaemia ": 14.840986533815109, "Incorrect dose administered ": 22.27189997292105, "Infusion site erythema ": 378.7068424793442, "Infusion site haemorrhage ": 262.73610743808274, "Infusion site induration ": 1638.7925262499334, "Infusion site inflammation ": 835.8845780395651, "Infusion site pain ": 1479.5861239778103, "Infusion site pruritus ": 468.8194607652781, "Infusion site swelling ": 121.98537586232004, "Injection site bruising ": 27.97931356491879, "Injection site erythema ": 13.669935236693926, "Injection site induration ": 17.396373382693593, "Injection site mass ": 43.04204303733281, "Injection site pain ": 15.211592454047496, "Injection site pruritus ": 13.984652241906804, "Injection site reaction ": 6.199753713454663, "Wrong technique in product usage process ": 9.733286507377985}
\ No newline at end of file
+{"Abdominal pain": 2.4284638987535034, "Alopecia": 3.0420841118096336, "Ascites": 5.0770647999392216, "Carcinoid crisis": 729.9988052503513, "Carcinoid syndrome": 372.307967345474, "Disease progression": 11.408197248332543, "Eating disorder": 6.5331749117395095, "Faeces soft": 27.946625081114437, "Flushing": 8.427859626246216, "Gastroenteropancreatic neuroendocrine tumour disease": 1591.4611163225388, "General physical health deterioration": 7.790425950770851, "Haematotoxicity": 30.436555517539382, "Hepatic failure": 3.095572143425118, "Ill-defined disorder": 70.3279944907816, "Illness": 4.355454135335968, "Inappropriate schedule of product administration": 3.8027043099293487, "Intentional product use issue": 4.972946445322618, "Intestinal obstruction": 11.951299568734497, "Jaundice": 2.697811465500182, "Laboratory test abnormal": 10.53113452785168, "Leukopenia": 5.279750198092759, "Lymphopenia": 30.395794333192743, "Malignant neoplasm progression": 11.689206230877357, "Metastases to liver": 17.84323881092934, "Myelodysplastic syndrome": 18.3515893862464, "Neoplasm progression": 6.787175024997808, "Neuroendocrine tumour": 432.6586984026894, "Neutropenia": 3.203783289701766, "Oral herpes": 6.461218656891535, "Pancreatic neuroendocrine tumour": 167.3917756535081, "Pancytopenia": 3.920631046771508, "Platelet count decreased": 4.628617844610371, "Renal impairment": 2.346583951436769, "Thrombocytopenia": 13.772082261252695, "Weight decreased": 2.060968086459456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/693.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/693.json
index 24d2d18496c..9cc2f124254 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/693.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/693.json
@@ -1 +1 @@
-{"Agranulocytosis ": 5.171829540164675, "Anaemia ": 2.1898920665727366, "Autoimmune haemolytic anaemia ": 57.82679205829911, "Bone marrow failure ": 29.362793696680864, "Cytomegalovirus infection ": 73.15110159435204, "Cytomegalovirus infection reactivation ": 77.28949380753357, "Guillain-Barre syndrome ": 13.43619225958807, "Hypotension ": 2.623383310914643, "Infection ": 2.892377519863435, "Leukopenia ": 4.59394493019408, "Lymphopenia ": 28.46581378946015, "Malignant neoplasm progression ": 2.2952875163023787, "Neutropenia ": 5.711085702770604, "Pancytopenia ": 12.059216786587651, "Pleural effusion ": 5.514504790889189, "Pneumonia ": 2.297403703866795, "Progressive multifocal leukoencephalopathy ": 67.38752508970668, "Sepsis ": 5.425476585432718, "Thrombocytopenia ": 5.158187948141624}
\ No newline at end of file
+{"Alopecia": 3.763309598438707, "Anaemia": 5.2412496160105055, "Blood pressure systolic increased": 19.2508836720835, "Body temperature decreased": 29.588294205029012, "Carcinoid crisis": 1264.3536851062606, "Constipation": 2.0435113117380914, "Disease progression": 2.279656577696442, "Eating disorder": 24.130595487623506, "Faeces soft": 61.352075302252274, "Haematotoxicity": 53.23100045612008, "Illness": 2.773754497421828, "Injection site mass": 24.14235755997068, "Leukopenia": 7.0114193676086245, "Malignant neoplasm progression": 7.052373895510567, "Myelodysplastic syndrome": 114.05385490438854, "Neoplasm progression": 6.259368173684158, "Nephropathy toxic": 17.83469840638457, "Product use in unapproved indication": 3.069725337517337, "Therapy partial responder": 29.74898920833145, "Thrombocytopenia": 14.07953545136616, "Weight decreased": 2.372011668793005}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/694.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/694.json
index 521112148cb..cceea0eb586 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/694.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/694.json
@@ -1 +1 @@
-{"Acute hepatitis B ": 79.25371624289451, "Acute myeloid leukaemia ": 4.141104142459735, "Acute respiratory distress syndrome ": 3.929758691381151, "Agranulocytosis ": 21.35592202430412, "Anaemia ": 2.2912328545258185, "B-cell lymphoma recurrent ": 87.60224945377034, "Bicytopenia ": 13.29593638447238, "Bone marrow failure ": 12.71043646351251, "Cardiac failure ": 2.4231624543484327, "Cardiomyopathy ": 4.673806257893796, "Cytomegalovirus infection ": 3.8908767942613873, "Cytopenia ": 12.448662665677974, "Dermatitis exfoliative generalised ": 5.151369433240756, "Diffuse large B-cell lymphoma recurrent ": 49.93232641021019, "Disease progression ": 4.188394116159946, "Disease recurrence ": 2.5983683547370484, "Ejection fraction decreased ": 3.183457138654644, "Febrile bone marrow aplasia ": 57.595154942346966, "Febrile neutropenia ": 20.043343567149268, "Full blood count decreased ": 6.508644197216642, "Granulocyte count decreased ": 37.55484819352679, "Granulocytopenia ": 12.533068739759791, "Haemoglobin decreased ": 2.2126612255206, "Hepatic cytolysis ": 3.685245391831023, "Hepatic failure ": 2.262710952945633, "Hepatitis B ": 12.968281761654218, "Hepatitis B reactivation ": 60.83092471733034, "Hyperpyrexia ": 2.147906795748211, "Hypogammaglobulinaemia ": 15.9027082667804, "Infection ": 3.3525329448264727, "Infusion related reaction ": 3.663189675439032, "Intentional product use issue ": 4.341645693306297, "Interstitial lung disease ": 6.6573274215883895, "Leukopenia ": 10.52508503688411, "Lung disorder ": 3.182178222229484, "Lung infiltration ": 4.979017783483184, "Lymphoma ": 4.692779402081943, "Lymphopenia ": 8.472184485878547, "Mucosal inflammation ": 4.347918998995172, "Multiple organ dysfunction syndrome ": 2.6259913780759443, "Myelodysplastic syndrome ": 5.493830037244657, "Myelosuppression ": 48.20506914867611, "Neurotoxicity ": 2.570163794905357, "Neutropenia ": 10.244090675135372, "Neutrophil count decreased ": 24.457928119942896, "Off label use ": 2.2604437681476903, "Pancytopenia ": 8.996925630102426, "Platelet count decreased ": 5.394000368332808, "Pneumocystis jirovecii pneumonia ": 44.47282078568343, "Pneumonia ": 3.0360029408749725, "Pneumonitis ": 5.992381102178824, "Polyneuropathy ": 7.078936670215466, "Progressive multifocal leukoencephalopathy ": 89.70245689681086, "Pulmonary fibrosis ": 5.333651518425477, "Respiratory tract infection ": 2.403266910951043, "Sepsis ": 3.1313110083870197, "Septic shock ": 6.096958661345178, "Splenomegaly ": 4.46286423994748, "Therapy partial responder ": 4.146999215443456, "Thrombocytopenia ": 4.222833880456496, "Tumour lysis syndrome ": 5.392357082724299, "White blood cell count decreased ": 18.83444965643559}
\ No newline at end of file
+{"Abdominal distension": 72.30939874493079, "Abdominal pain": 13.967377139578474, "Ovarian hyperstimulation syndrome": 856.7378404412825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/695.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/695.json
index 67ab6a534f4..0d01a7b5e5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/695.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/695.json
@@ -1 +1 @@
-{"Bone deformity ": 25827.71185109847, "Graft complication ": 69022.96824143936, "Transplant failure ": 2971.3211525250745}
\ No newline at end of file
+{"Abdominal distension": 63.366491315461104, "Abdominal pain": 13.562397155142616, "Abdominal pain lower": 41.22377280101578, "Ascites": 23.48742004773497, "Chest discomfort": 6.016676134315127, "Dyspnoea": 2.5839917077974848, "Nausea": 2.0954353010680973, "Ovarian hyperstimulation syndrome": 1783.289084149633, "Vomiting": 2.9644297582507013, "Waist circumference increased": 1068.125355537261}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/696.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/696.json
index 8881a4046c8..0f626bbdaf6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/696.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/696.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.328803829800042, "Ascites ": 5.7853181420963065, "Blood pressure decreased ": 4.974155018442401, "Condition aggravated ": 2.2083024410575582, "Disease progression ": 4.7011009169207, "Dyspnoea ": 2.8255215718145386, "Epistaxis ": 2.138690056870184, "Fluid retention ": 14.26391008373622, "Flushing ": 4.199914013289733, "Haemorrhage subcutaneous ": 19.83906753344544, "Hospitalisation ": 4.638759975209124, "Hypervolaemia ": 22.433644452740907, "Hypotension ": 2.714791499348781, "Hypoxia ": 4.651527694551911, "Internal haemorrhage ": 31.748197089288187, "Nasal congestion ": 4.351811208284828, "Oedema ": 2.36331364297496, "Oedema peripheral ": 3.568872015586262, "Pain in jaw ": 17.636502907876174, "Pericardial effusion ": 9.248181935817447, "Peripheral swelling ": 2.4832690818304566, "Pleural effusion ": 2.7701980531758794, "Pneumonia ": 2.944094474471761, "Post procedural haemorrhage ": 25.313683515697647, "Product administration interrupted ": 128.55663112788406, "Product use issue ": 3.662669903703475, "Pulmonary arterial hypertension ": 94.37490313307072, "Pulmonary hypertension ": 34.310280620018325, "Pulmonary oedema ": 11.238829984801614, "Right ventricular failure ": 45.90248476607123, "Shock haemorrhagic ": 19.20432157929326, "Syncope ": 2.602529832754711, "Vascular device infection ": 70.31561265457778}
\ No newline at end of file
+{"Blindness": 29.528157804574704, "Intraocular pressure increased": 429.7422670112431, "Photophobia": 33.09864119134382, "Retinal degeneration": 8002.012273288915, "Retinal deposits": 9965.152892245856, "Retinal detachment": 305.5062079943043, "Retinal tear": 709.9379170442716, "Vision blurred": 8.636445954402651, "Visual impairment": 15.390855893424083}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/697.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/697.json
index 6bf8617980a..334ed1c6e2b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/697.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/697.json
@@ -1 +1 @@
-{"Acute kidney injury ": 6.722012458829095, "Alanine aminotransferase increased ": 3.978084233443691, "Altered state of consciousness ": 5.262091304159024, "Anaphylactic reaction ": 2.537626793672219, "Arrhythmia ": 2.8696161635906186, "Aspartate aminotransferase increased ": 8.81175030362971, "Blood alkaline phosphatase increased ": 7.087680750848746, "Blood bilirubin increased ": 6.658724086828021, "Blood lactate dehydrogenase increased ": 10.213913209647584, "Blood lactic acid increased ": 36.55478555195216, "Bradycardia foetal ": 120.68706507158598, "Brain oedema ": 20.95745080810684, "Cardiomyopathy ": 16.42023319680405, "Disease progression ": 3.117213923467475, "Disseminated intravascular coagulation ": 8.881459736169768, "Drug ineffective ": 2.689694827373577, "Foetal exposure during pregnancy ": 3.0986054003782653, "Gamma-glutamyltransferase increased ": 5.852570473464167, "Gastrointestinal disorder ": 3.216957661056536, "Hepatic function abnormal ": 5.592244400988305, "Hypokalaemia ": 3.987309188677058, "Hyponatraemia ": 4.607503304319176, "Hypotension ": 2.2072612863967334, "Intraocular pressure increased ": 23.955267672282307, "Low birth weight baby ": 14.254371169103957, "Metabolic acidosis ": 7.857124829315548, "Myelosuppression ": 22.981492639911885, "Nephropathy toxic ": 19.14072067562964, "Palmar erythema ": 133.11433221108734, "Platelet count decreased ": 2.359311898350774, "Premature baby ": 8.642685573808313, "Productive cough ": 6.105726415386842, "Respiratory failure ": 3.86729493061424, "Rhabdomyolysis ": 3.344413496146685, "Toxic epidermal necrolysis ": 18.609102870062333, "White blood cell count decreased ": 2.602616067140603, "Withdrawal hypertension ": 843.2177030145225}
\ No newline at end of file
+{"Acute leukaemia": 15.199785051210522, "Acute myeloid leukaemia": 25.178493153297406, "Adverse drug reaction": 2.215978195521097, "Anaemia": 34.191966963231565, "Ascites": 3.709310540159764, "Blood creatinine increased": 2.731094829683042, "Blood test abnormal": 2.4439231246484376, "Carbohydrate antigen 125 increased": 312.5016257055552, "Creatinine renal clearance decreased": 2.8380367604013723, "Decreased appetite": 2.6423170534321625, "Disease progression": 3.344384547684107, "Disease recurrence": 2.1552986605033952, "Erythema nodosum": 4.23001175676799, "Feeding disorder": 2.3676459474474, "Full blood count abnormal": 2.134481421043976, "Full blood count decreased": 2.6267400513663084, "Glomerular filtration rate decreased": 3.350114791446407, "Haematotoxicity": 20.220523194314836, "Haemoglobin decreased": 8.03816984367346, "Ileus": 14.333372117004169, "Interstitial lung disease": 8.115904964249822, "Intestinal obstruction": 4.633413372442902, "Laboratory test abnormal": 2.687254500435971, "Leukaemia": 7.244958886068466, "Leukopenia": 2.4375100473526747, "Malignant neoplasm progression": 21.81752510123498, "Metastases to bone": 7.85483579204389, "Metastases to central nervous system": 15.60927396701696, "Metastases to liver": 6.364523857299057, "Metastases to lung": 3.5076420958540124, "Metastases to lymph nodes": 10.980605142565247, "Metastases to meninges": 10.914184310791969, "Metastases to peritoneum": 30.615660597831265, "Metastases to spine": 10.113831741203056, "Metastasis": 20.477532780170066, "Myelodysplastic syndrome": 66.9199319794156, "Myelosuppression": 4.741923936233382, "Nausea": 2.778741853503857, "Neoplasm": 5.273056498402237, "Neutropenia": 3.687953064598596, "Neutrophil count decreased": 16.131385590034768, "No adverse event": 5.72571484847963, "Off label use": 2.8955486637333365, "Ovarian cancer": 13.915296651010422, "Ovarian cancer recurrent": 856.5156125474496, "Pancytopenia": 4.858133280959089, "Platelet count decreased": 8.070517206962602, "Pneumocystis jirovecii pneumonia": 3.961157915100298, "Pneumonitis": 4.9431038216057335, "Product dose omission issue": 2.306292218084797, "Product use complaint": 6.032828502370213, "Product use in unapproved indication": 2.2282228490334064, "Prostatic specific antigen increased": 12.805102644598067, "Pulmonary toxicity": 2.831017124228476, "Recurrent cancer": 34.686911872857614, "Red blood cell count decreased": 5.51348373286463, "Renal impairment": 2.872978421470666, "Stomatitis": 2.2701260953007023, "Taste disorder": 6.617552655954723, "Thrombocytopenia": 4.644053060836868, "Tumour marker increased": 47.97801204901999, "White blood cell count decreased": 3.8019709571676144}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/698.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/698.json
index 94d15d3a01b..a4d7f6099a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/698.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/698.json
@@ -1 +1 @@
-{"Back pain ": 4.099885419004326, "Pneumonia ": 4.133408481761401}
\ No newline at end of file
+{"Abnormal behaviour": 2.3044147632241634, "Accident at work": 7.895300222220611, "Aggression": 2.502177153844869, "Agitation": 2.149291764039708, "Altered state of consciousness": 3.527660835278154, "Amnesia": 3.278627816727175, "Aneurysm": 2.050026813316709, "Anger": 2.882818904409927, "Ankle fracture": 2.264708260048224, "Ataxia": 3.209151712420696, "Back disorder": 10.104154784621764, "Back injury": 3.897744354681757, "Balance disorder": 2.380237847770708, "Bedridden": 2.221726217421444, "Behaviour disorder": 2.402661176498017, "Bipolar disorder": 2.118496781426703, "Bladder disorder": 2.590664810996554, "Blood disorder": 2.3173322770080422, "Blood pressure abnormal": 3.528449076580614, "Blood sodium decreased": 2.1159714534825347, "Blood testosterone decreased": 3.07494840240443, "Body height decreased": 6.77119319297698, "Bradyphrenia": 2.3001987402126534, "Bradypnoea": 4.251876728783902, "Brain injury": 2.3337403747797683, "Breakthrough pain": 16.525053810660133, "Burning sensation": 2.315353011001159, "Central nervous system lesion": 2.038684290983202, "Cerebral disorder": 2.760526081839542, "Cholestasis": 2.4178170218807864, "Chronic obstructive pulmonary disease": 2.2556359817082177, "Coma": 4.782005572434374, "Complex regional pain syndrome": 4.574626162044443, "Concussion": 4.258260591748541, "Confusional state": 3.559283848051942, "Craniocerebral injury": 4.434507945980699, "Crepitations": 4.739472695522146, "Delirium": 2.4551177804461592, "Delusion": 2.097839379479247, "Dementia": 2.385588692317832, "Depressed level of consciousness": 3.1510290484650034, "Depression": 2.4188051939607336, "Diabetes mellitus": 2.8725444016270245, "Diabetic neuropathy": 7.809821889133977, "Diplopia": 3.0515211474497232, "Disorientation": 3.1251853777569183, "Disturbance in attention": 2.156608046559099, "Dizziness exertional": 9.742299963809849, "Drug abuse": 4.528757954297011, "Drug abuser": 4.989802007567006, "Drug dependence": 4.188221714357229, "Drug diversion": 5.608239767139101, "Drug hypersensitivity": 2.089045970164773, "Drug ineffective for unapproved indication": 3.0785284613482045, "Drug interaction": 2.870936488265804, "Drug tolerance": 2.2252912498015185, "Drug use disorder": 4.708137716483887, "Drug withdrawal syndrome": 2.102057447103009, "Dry mouth": 2.288654249829285, "Dysarthria": 2.7875695280969293, "Dyskinesia": 2.511392797851753, "Dysphemia": 3.002773352252828, "Dysstasia": 2.320142687081783, "Emotional disorder": 2.1818009061172, "Endometriosis": 3.9065518114704, "Essential hypertension": 3.239136847301827, "Euphoric mood": 5.308550300215815, "Exostosis": 2.441455230714451, "Eye contusion": 10.758311890535872, "Fall": 3.896075276322932, "Fear": 2.7157770370146155, "Feeling abnormal": 3.781949156742369, "Feeling drunk": 6.431042855590051, "Fibromyalgia": 6.98306858402557, "Fluid retention": 2.090539988993989, "Foot fracture": 2.261441528886728, "Gait disturbance": 2.9940706217939344, "Gait inability": 2.677613666943335, "Gastrointestinal sounds abnormal": 2.8219663282558787, "Generalised anxiety disorder": 5.570319794721856, "Hallucination": 3.01621985219676, "Hallucination, visual": 3.1895343788591046, "Hallucinations, mixed": 2.994046826317976, "Head injury": 2.987607146003576, "Hepatic cytolysis": 3.4106466069413908, "Hernia": 5.406122981796719, "Hyperlipidaemia": 2.662946656003094, "Hypersomnia": 2.2237478970065734, "Hyporeflexia": 2.717902286339948, "Illness": 2.333842415639686, "Impaired driving ability": 9.840583200536145, "Increased appetite": 2.714810856208345, "Infective exacerbation of chronic obstructive airways disease": 26.16378059523933, "Intentional overdose": 3.500605531905709, "Intentional product misuse": 4.145703330790836, "Intentional self-injury": 3.449943269395068, "Intervertebral disc degeneration": 3.2875249321616296, "Intervertebral disc disorder": 4.946355547623246, "Intervertebral disc protrusion": 9.01506107978662, "Joint injury": 2.0958765396681365, "Ligament sprain": 3.902849545761827, "Lip erosion": 7.276537823834903, "Logorrhoea": 2.780618045764589, "Loss of consciousness": 2.093926274165291, "Loss of control of legs": 6.751319415839402, "Lower limb fracture": 2.793669851973885, "Memory impairment": 4.224957427308937, "Mental impairment": 2.8883225318105312, "Miosis": 4.5529520558998975, "Multiple sclerosis": 2.5903590667814145, "Muscle contractions involuntary": 2.344325807211219, "Muscle disorder": 4.391432663931055, "Muscle spasticity": 4.900513318720591, "Mydriasis": 2.4131123186520544, "Myoclonus": 6.47233727556663, "Near death experience": 4.790168570266594, "Neck injury": 7.538275676326467, "Nerve compression": 4.998473631575979, "Nerve injury": 8.558186545403876, "Nervousness": 2.4624703621063126, "Neuralgia": 4.447104609253191, "Neuropathy peripheral": 2.6464201949747066, "Obesity": 2.047288944678132, "Oedema peripheral": 2.124701791339147, "Oral mucosa erosion": 4.394531767096284, "Overdose": 2.260802787769693, "Overweight": 2.724130682166755, "Panic attack": 2.857509797062542, "Partial seizures": 2.060832682739202, "Peroneal nerve palsy": 3.036231005527762, "Persecutory delusion": 3.3330717688085696, "Pneumonia aspiration": 3.274547579751329, "Poisoning": 3.083319485331353, "Poisoning deliberate": 4.086591611608244, "Post herpetic neuralgia": 6.389100903772428, "Post-traumatic stress disorder": 4.85131486542355, "Potentiating drug interaction": 5.170140511808287, "Pre-existing condition improved": 7.159491399975495, "Prescription drug used without a prescription": 2.697621022992174, "Psychomotor hyperactivity": 2.197467492393769, "Pulmonary thrombosis": 3.140868460168761, "Pulmonary vascular resistance abnormality": 189.40649565766608, "Raynaud's phenomenon": 2.059392153594191, "Respiratory depression": 3.503742198403054, "Respiratory rate decreased": 9.057045799591208, "Rhabdomyolysis": 2.883335070749042, "Road traffic accident": 6.228408289677032, "Sciatica": 2.767075263913238, "Sedation": 3.2076871985432827, "Sensory loss": 2.750418624739144, "Sinus disorder": 2.117225735028589, "Sjogren's syndrome": 2.897113537690764, "Sleep apnoea syndrome": 3.2693413975107064, "Small intestinal obstruction": 2.51367092477118, "Social avoidant behaviour": 2.2281588643902586, "Somnambulism": 3.384883499093425, "Somnolence": 4.275662639846469, "Sopor": 5.673017458807636, "Speech disorder": 3.7464520047939502, "Spinal column injury": 6.658362866991502, "Spinal disorder": 12.686892763407766, "Spinal fracture": 2.605568279124496, "Spinal fusion surgery": 4.607866334581137, "Spinal operation": 3.124873167245155, "Spinal stenosis": 3.1673975766663385, "Substance use disorder": 3.103860242551961, "Sudden onset of sleep": 5.415252313638984, "Suicidal ideation": 2.7923531635555747, "Suicide attempt": 3.543504669553104, "Thinking abnormal": 6.1209288280584, "Thyroid function test abnormal": 5.147317622658074, "Toxic encephalopathy": 2.218586326170255, "Type 2 diabetes mellitus": 2.122791008798918, "Underdose": 2.6439670499494308, "Upper limb fracture": 2.949667461133713, "Urinary incontinence": 2.424918931393877, "Urinary retention": 3.2422165366087485, "Urine abnormality": 3.161600858311834, "Vision blurred": 2.4585682324891613, "Vitamin B12 deficiency": 3.3795395163595043, "Vitamin D decreased": 3.011550896119146, "Weight increased": 5.087634613018581, "Weight loss poor": 3.9290047110071926, "Withdrawal syndrome": 7.04495950750995, "Wrong patient received product": 4.61745672815892}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/699.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/699.json
index afa7f1d2986..d53d6850b39 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/699.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/699.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.4906783256451277, "Acne ": 2.635085311351826, "Alanine aminotransferase increased ": 5.8258627480972045, "Alopecia ": 6.562565434225435, "Aspartate aminotransferase increased ": 5.061810481386424, "Breast cancer ": 2.1640453128530317, "COVID-19 ": 2.2894308681030706, "Central nervous system lesion ": 10.44359074066859, "Diplopia ": 2.2777941921831943, "Drug-induced liver injury ": 2.164991269747034, "Expanded disability status scale score increased ": 723.4151365460845, "Gamma-glutamyltransferase increased ": 4.950399284891678, "Herpes simplex ": 13.868369911307, "Herpes zoster ": 6.673886345570021, "Leukopenia ": 2.39433463064217, "Live birth ": 5.838032820397292, "Lymphocyte count decreased ": 326.85481159665795, "Lymphopenia ": 245.25829444617733, "Maternal exposure before pregnancy ": 35.14603627754939, "Maternal exposure timing unspecified ": 18.5411422160925, "Multiple sclerosis ": 77.61281487196355, "Multiple sclerosis relapse ": 175.07429808851833, "Nasopharyngitis ": 4.2182235135714405, "Neutrophil count decreased ": 2.499546350397545, "Optic neuritis ": 12.2719335947408, "Oral herpes ": 18.53042827262662, "Product administration error ": 2.096463515476069, "Sensory disturbance ": 2.6691916818738584, "Upper respiratory tract infection ": 4.740294137978795, "Urinary tract infection ": 4.977302044010598, "White blood cell count decreased ": 5.205688873491689}
\ No newline at end of file
+{"Adrenal insufficiency": 44.281390988049765, "Asthenia": 2.088099750439408, "Decreased appetite": 2.039263361268088, "Disturbance in attention": 5.628209468934589, "Gamma-glutamyltransferase increased": 12.242512024210331, "General physical health deterioration": 4.466366245119725, "Hepatic enzyme increased": 5.57478748706496, "Hypokalaemia": 3.327568512886822, "Hypothyroidism": 7.792186168294314, "Malignant neoplasm progression": 7.1671120220053, "Memory impairment": 3.0518598258782337, "Off label use": 2.103920069126632, "Somnolence": 3.620104568250559, "Vertigo": 2.235873749672955, "Vomiting": 2.237818048263976, "Weight decreased": 3.508755933564427}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/7.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/7.json
index 3f4f5e0f797..3965e873089 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/7.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/7.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 3.675425746243086, "Abnormal weight gain ": 3.6563687570220855, "Accident ": 3.7244892433680135, "Accommodation disorder ": 4.318415133287264, "Adverse drug reaction ": 3.5350140969338937, "Affective disorder ": 3.127977635794941, "Aggression ": 7.282472135830056, "Agitation ": 3.349745374987725, "Akathisia ": 58.88661279333641, "Alcoholism ": 7.529271427556875, "Allergy to animal ": 7.597548083916496, "Amphetamines positive ": 19.97850996290246, "Analgesic drug level above therapeutic ": 269.13885103715563, "Anger ": 4.138060861153133, "Anorgasmia ": 6.923220431133673, "Anosognosia ": 811.7473321207051, "Antidepressant drug level above therapeutic ": 66.62300005378003, "Antipsychotic drug level below therapeutic ": 237.50794988698203, "Antipsychotic drug level increased ": 3.860186491583365, "Anxiety ": 2.3224671878730354, "Anxiety disorder ": 9.072679408953784, "Apathy ": 5.275930599594846, "Atrophy ": 24.360455772253943, "Attention deficit hyperactivity disorder ": 2.071235623122248, "Behaviour disorder ": 2.1206745283380566, "Binge eating ": 14.41324561334187, "Bipolar I disorder ": 5.5813945059498815, "Bipolar disorder ": 15.764130373977425, "Blood bicarbonate decreased ": 9.1049112387039, "Blood creatine phosphokinase increased ": 3.0012784991716672, "Blood creatinine decreased ": 4.443707301634298, "Blood glucose increased ": 2.7669754743843997, "Blood prolactin abnormal ": 1364.0484434078382, "Blood prolactin increased ": 11.718153295184276, "Blood triglycerides increased ": 2.604114978135373, "Body temperature abnormal ": 2.296994289177632, "Body temperature decreased ": 2.4353530300096207, "Borderline personality disorder ": 14.74527624607922, "Botulism ": 64.09943774249, "Bradykinesia ": 2.265202411747282, "Bradyphrenia ": 2.257940766582806, "Breech presentation ": 79.98185158090354, "Bruxism ": 6.649561515372604, "Bundle branch block right ": 2.438039539429133, "Caesarean section ": 9.982037308704705, "Calcium ionised decreased ": 83.35343939989477, "Catatonia ": 3.995800109314074, "Cleft lip and palate ": 5.813513897146685, "Cogwheel rigidity ": 4.788458877734608, "Coma ": 2.072918949795687, "Communication disorder ": 2.0631288399651333, "Compulsive sexual behaviour ": 66.12822527511668, "Compulsive shopping ": 56.928017852095344, "Concussion ": 3.610408947119077, "Contrast media allergy ": 7.9707485302043395, "Decreased interest ": 3.9465863074468337, "Delusion ": 8.467168362173059, "Delusional disorder, persecutory type ": 152.4840657694575, "Depressed level of consciousness ": 2.198927377811663, "Depression ": 2.8090712789857384, "Depressive symptom ": 3.2467226465185983, "Derealisation ": 2.789014043641911, "Diabetes mellitus ": 7.160985152346186, "Dialysis ": 4.603195056511371, "Disability ": 2.2401280234567853, "Disease recurrence ": 2.3366401785817024, "Disinhibition ": 138.02771173803418, "Disturbance in social behaviour ": 203.7405551609328, "Drooling ": 3.2572314748298234, "Drug effective for unapproved indication ": 4.502342035523024, "Drug interaction ": 2.6554956201486, "Drug withdrawal syndrome neonatal ": 5.645905256300755, "Dry eye ": 2.771828459275965, "Dust allergy ": 4.110600996032065, "Dyskinesia ": 15.692865848775693, "Dyskinesia neonatal ": 78.76470344929817, "Dyslipidaemia ": 40.78053740906228, "Dystonia ": 39.17464153176729, "Eating disorder ": 3.2096263907320277, "Electrocardiogram QT prolonged ": 3.516840318054676, "Emotional disorder ": 4.240201602179114, "Emotional poverty ": 5.3245266242829, "Enuresis ": 3.2189303916592835, "Euphoric mood ": 43.05277876806922, "Exposure via breast milk ": 3.311328262070821, "Extrapyramidal disorder ": 16.605309826226417, "Fear ": 2.457177193388966, "Feeling guilty ": 10.543807530742638, "Feeling of despair ": 4.05434602716916, "Flank pain ": 5.12408247548939, "Flat affect ": 5.291493372011236, "Foetal distress syndrome ": 13.232820404473838, "Foetal exposure during pregnancy ": 3.3994615804209625, "Foetal growth restriction ": 3.2586469485929896, "Foetal heart rate decreased ": 8.86688467539991, "Food craving ": 4.168067091307857, "Galactorrhoea ": 7.464655617758531, "Gambling disorder ": 26.91008209519553, "Gestational diabetes ": 14.376328160011749, "Gestational hypertension ": 24.29753753268703, "Glucose tolerance impaired ": 4.60899047970853, "Gynaecomastia ": 5.557026528778535, "Haemangioma ": 3.315247620901477, "Haematocrit decreased ": 2.4875027140086776, "Hallucination, auditory ": 15.51193521210926, "Hallucination, visual ": 2.330773930251467, "Hallucinations, mixed ": 43.53443381646376, "Homicidal ideation ": 4.973334938760129, "Humidity intolerance ": 86.95783755460094, "Hunger ": 2.830918110374303, "Hyperphagia ": 5.832356104265439, "Hyperprolactinaemia ": 10.5796509433522, "Hypersomnia ": 2.049972688583395, "Hypertension ": 2.605814546966234, "Hyperthermia ": 2.4099568667395035, "Hypoaesthesia eye ": 197.26203943944765, "Hypoglycaemia neonatal ": 7.045818457262448, "Hypomania ": 3.697783357189534, "Hypothermia ": 2.727639078176121, "Hypothyroidism ": 4.175130506125828, "Hypoxic-ischaemic encephalopathy ": 10.157120966813215, "Impatience ": 22.87384207231726, "Impulse-control disorder ": 16.75123112795543, "Impulsive behaviour ": 12.273953157695423, "Inability to afford medication ": 8.930202475636476, "Inappropriate schedule of product administration ": 2.3380392031523503, "Increased appetite ": 33.11811341749913, "Infarction ": 6.195724303536501, "Infertility ": 10.184574056984806, "Insomnia ": 2.223457826243262, "Insurance issue ": 35.8062619548615, "Intentional overdose ": 3.772529946033434, "Intentional self-injury ": 5.965053291818346, "International normalised ratio abnormal ": 6.730385310330717, "Intestinal obstruction ": 2.3371158770762417, "Intrusive thoughts ": 14.927222602381876, "Irritability ": 6.647982920703926, "Jaundice neonatal ": 16.503846071316257, "Joint effusion ": 5.74953079535982, "Large for dates baby ": 12.734298551573785, "Left ventricular dysfunction ": 5.33035179267404, "Leukaemia ": 32.42495844778806, "Leukopenia ": 4.383188797993573, "Libido decreased ": 2.9038114404415607, "Libido increased ": 4.705213970829912, "Ligament sprain ": 3.3090728013630875, "Live birth ": 7.838143885716013, "Loss of employment ": 4.889162168256731, "Loss of libido ": 4.214250623596751, "Major depression ": 4.748040716114136, "Mania ": 11.54587732904396, "Mastication disorder ": 5.240389297729403, "Maternal exposure during pregnancy ": 3.874135695304656, "Memory impairment ": 3.134575846333691, "Menopause ": 4.8554980416227576, "Mental disorder ": 4.886333254395177, "Mental impairment ": 3.039389038283853, "Metabolic disorder ": 83.15517160287843, "Metabolic syndrome ": 29.55024842669443, "Milk allergy ": 10.856886804758512, "Mixed liver injury ": 3.634086902597341, "Mood altered ": 2.954844296794644, "Muscle contracture ": 3.1551888221935767, "Muscle disorder ": 2.947294244670653, "Muscle rigidity ": 4.703394246839595, "Mutism ": 6.850632482819692, "Mycotic allergy ": 4.907725424495013, "Mydriasis ": 2.359942946443465, "Myofascial pain syndrome ": 47.29777488164353, "Negative thoughts ": 3.763533281688927, "Neonatal respiratory distress ": 18.546648288026617, "Neonatal respiratory distress syndrome ": 4.270081839263074, "Neuroleptic malignant syndrome ": 15.226735240454625, "Normal newborn ": 6.236304935827589, "Obesity ": 33.18425407466267, "Obsessive-compulsive disorder ": 73.19126478121633, "Oculogyric crisis ": 28.628464108084536, "Ophthalmoplegia ": 3.656175965973194, "Oropharyngeal discomfort ": 7.23488701428434, "Orthostatic hypertension ": 111.36976972814588, "Overdose ": 2.333792449099305, "Panic disorder ": 2.140331538996817, "Panic reaction ": 8.749059074626432, "Paranoia ": 3.6071599831000976, "Parkinson's disease ": 2.606553734423559, "Parkinsonism ": 18.565155826930127, "Patient elopement ": 19.17713849898944, "Perinatal depression ": 30.666410785618048, "Persecutory delusion ": 4.397965829307505, "Persistent depressive disorder ": 11.225204172208752, "Personal relationship issue ": 12.03718113707504, "Personality change ": 36.76274515306304, "Personality change due to a general medical condition ": 127.7461421799497, "Personality disorder ": 8.349169416418253, "Piloerection ": 6.719464659881618, "Pleurothotonus ": 11.008924038585253, "Pneumonia aspiration ": 2.252954259495824, "Poisoning deliberate ": 2.921610012116054, "Polyuria ": 3.5458609860547385, "Poor feeding infant ": 5.574032999273601, "Post-traumatic stress disorder ": 2.3970855859714644, "Posture abnormal ": 10.40767395781147, "Potentiating drug interaction ": 2.367437073774622, "Pregnancy ": 4.791669390296495, "Premature baby ": 6.548518918479444, "Premature delivery ": 6.642401606456948, "Premature labour ": 3.4091642539582856, "Prescribed overdose ": 14.971827050956584, "Prescribed underdose ": 6.380167763945899, "Product dose omission issue ": 2.2117073725754888, "Product use in unapproved indication ": 5.033011443581888, "Psychiatric decompensation ": 9.615305348013736, "Psychiatric symptom ": 5.616737573158261, "Psychomotor hyperactivity ": 4.158956068754716, "Psychomotor retardation ": 4.697350117455549, "Psychomotor skills impaired ": 4.582932270202171, "Psychotic disorder ": 17.89131769235133, "Psychotic symptom ": 32.83947208469103, "Refusal of treatment by patient ": 10.889222495940286, "Restless legs syndrome ": 2.9236414487355464, "Restlessness ": 4.191271032900143, "Rhabdomyolysis ": 2.330241846867506, "Rhesus incompatibility ": 2170.426636709448, "Rubber sensitivity ": 10.028048987094346, "Salivary hypersecretion ": 4.663403950523844, "Schizoaffective disorder ": 86.50235992561116, "Schizophrenia ": 47.54435432793934, "Schizophreniform disorder ": 25.378071839638825, "Screaming ": 2.157681560492145, "Sedation ": 25.499697330069573, "Self-destructive behaviour ": 6.792979480540944, "Self-injurious ideation ": 2.710593751162179, "Sepsis neonatal ": 18.34742069640324, "Serotonin syndrome ": 3.057834389864757, "Sexual dysfunction ": 53.201182762049015, "Social anxiety disorder ": 8.345624915886523, "Social avoidant behaviour ": 15.426590235610645, "Social fear ": 47.904674034745575, "Somatic symptom disorder ": 18.37543113785225, "Sopor ": 4.072121364993928, "Staphylococcal infection ": 7.904162504974314, "Status epilepticus ": 2.3632228596190266, "Stubbornness ": 111.7568272976294, "Stupor ": 2.7600823538025265, "Substance abuse ": 3.5263130986333024, "Substance use ": 287.73242157640954, "Substance-induced psychotic disorder ": 21.314506958951185, "Sudden cardiac death ": 6.061196339269173, "Suicidal behaviour ": 2.457773213672281, "Suicidal ideation ": 4.838090286753683, "Suicide attempt ": 15.295255075273252, "Symptom recurrence ": 14.386164822575331, "Tachyphrenia ": 5.41640874309355, "Tardive dyskinesia ": 26.24833478342308, "Tension ": 2.224285691146488, "Therapeutic product effect incomplete ": 6.062170272622497, "Therapeutic product effect variable ": 163.82787596914008, "Therapy cessation ": 4.841348670567941, "Therapy change ": 3.113166326444243, "Therapy non-responder ": 2.293477831493164, "Thermal burn ": 34.178912544689204, "Thinking abnormal ": 6.098253062154013, "Throat tightness ": 3.339873002426077, "Tic ": 6.4360146466369, "Toxicity to various agents ": 4.5175373092797, "Transfusion ": 3.281012722375777, "Transient tachypnoea of the newborn ": 47.03481217766212, "Treatment noncompliance ": 7.779769719925113, "Tremor ": 2.1176274035231084, "Type 2 diabetes mellitus ": 2.077054226881724, "Underdose ": 2.7587993031230345, "Unemployment ": 53.00269818008081, "Urinary hesitation ": 4.544969972524501, "Ventricular arrhythmia ": 2.1243181289650934, "Violence-related symptom ": 6.051443351995413, "Weight fluctuation ": 5.700783215477451, "Weight increased ": 9.858281419258695, "Wound ": 5.417214867592367, "Wound complication ": 30.55285461905696, "Wrong technique in product usage process ": 3.3895779553668515}
\ No newline at end of file
+{"Anaemia": 2.4617573956389687, "Blood bilirubin increased": 6.925106015555614, "Breast cancer metastatic": 93.15999432842683, "Diarrhoea": 3.853936042933469, "Disease progression": 3.1412143460413438, "Malignant neoplasm progression": 17.71103368606872, "Metastases to bone": 81.60225083279639, "Metastases to liver": 45.60456660337498, "Metastases to lung": 37.63510260335623, "Metastatic neoplasm": 107.1257911622265, "Myelosuppression": 20.66017116223991, "Neuropathy peripheral": 3.653065222941838, "Neutropenia": 4.333085332063307, "Neutrophil count decreased": 5.8981201708660285, "Platelet count decreased": 5.768634076520544, "Tumour marker increased": 96.50616766760608, "White blood cell count decreased": 3.8952560166661834}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/70.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/70.json
index 3db954d2d0f..e8ff29e6010 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/70.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/70.json
@@ -1 +1 @@
-{"Balance disorder ": 34.13441854842257, "Blood calcium decreased ": 264.26574021931714, "Cognitive disorder ": 63.71014152609484, "Constipation ": 17.15046578978299, "Creatinine renal clearance decreased ": 334.2392335047507, "Creatinine renal clearance increased ": 909.540138114541, "Depressed level of consciousness ": 44.3927610565479, "Dyspnoea ": 3.196263937907502, "Fall ": 11.897991469564742, "Hypotension ": 11.708560867906748, "Mobility decreased ": 42.02602056409437, "Multiple drug therapy ": 1266.7035623438549, "Orthostatic hypotension ": 100.3802837771256, "Pain ": 3.943724599579484, "Product use in unapproved indication ": 3.1539639476941272, "Renal function test abnormal ": 236.61149787421976, "Sedation ": 111.98748844841803, "Sedation complication ": 362.1595705485053, "Toxicity to various agents ": 16.72914899626805}
\ No newline at end of file
+{"Ventricular tachycardia": 52.8856459910641}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/700.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/700.json
index 52f7df9ab56..d33b2608f02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/700.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/700.json
@@ -1 +1 @@
-{"Drug ineffective ": 2.348361662567159}
\ No newline at end of file
+{"Blood glucose abnormal": 35.67015555704494, "Blood glucose decreased": 12.020110699608816, "Blood glucose fluctuation": 29.7734680108193, "Blood glucose increased": 29.78010194026098, "Drug ineffective": 2.2642497122148675, "Expired product administered": 15.131490389792624, "Glycosylated haemoglobin increased": 23.480798525429787, "Hyperglycaemia": 16.941635120085436, "Hypoglycaemia": 14.840485089462495, "Incorrect dose administered": 22.27189997292105, "Infusion site erythema": 378.7068424793442, "Infusion site haemorrhage": 262.73610743808274, "Infusion site induration": 1638.7925262499334, "Infusion site inflammation": 835.8845780395651, "Infusion site pain": 1479.5861239778103, "Infusion site pruritus": 468.8194607652781, "Infusion site swelling": 121.98537586232004, "Injection site bruising": 27.97931356491879, "Injection site erythema": 13.669935236693926, "Injection site induration": 17.396373382693593, "Injection site mass": 43.04204303733281, "Injection site pain": 15.21140167095309, "Injection site pruritus": 13.984652241906804, "Injection site reaction": 6.199753713454663, "Wrong technique in product usage process": 9.733286507377985}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/701.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/701.json
index c5f59688f1d..3b8f8808936 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/701.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/701.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 8.203096816302743, "Abdominal pain lower ": 53.635991976801535, "Contusion ": 12.902804217982728, "Eye haemorrhage ": 77.41697412515178, "Hypoaesthesia ": 7.042494970994402, "Multiple sclerosis ": 92.35270030804791, "Musculoskeletal stiffness ": 12.858548505148864, "Vomiting ": 2.204069747062679}
\ No newline at end of file
+{"Agranulocytosis": 5.171829540164675, "Anaemia": 2.1898920665727366, "Autoimmune haemolytic anaemia": 57.82679205829911, "Bone marrow failure": 29.362793696680864, "Cytomegalovirus infection": 73.15110159435204, "Cytomegalovirus infection reactivation": 77.28949380753357, "Guillain-Barre syndrome": 13.43619225958807, "Hypotension": 2.62332266335627, "Infection": 2.892377519863435, "Leukopenia": 4.593365867910453, "Lymphopenia": 28.46581378946015, "Malignant neoplasm progression": 2.2952875163023787, "Neutropenia": 5.710840077372046, "Pancytopenia": 12.059216786587651, "Pleural effusion": 5.513997089276398, "Pneumonia": 2.297403703866795, "Progressive multifocal leukoencephalopathy": 67.38752508970668, "Sepsis": 5.425476585432718, "Thrombocytopenia": 5.157702651165423}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/702.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/702.json
index e1994314a43..6c49f0c43d3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/702.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/702.json
@@ -1 +1 @@
-{"Cardiomyopathy ": 117.02464658818084}
\ No newline at end of file
+{"Acute hepatitis B": 79.25371624289451, "Acute myeloid leukaemia": 4.141104142459735, "Acute respiratory distress syndrome": 3.929758691381151, "Agranulocytosis": 21.35592202430412, "Anaemia": 2.2912328545258185, "B-cell lymphoma recurrent": 87.60224945377034, "Bicytopenia": 13.29593638447238, "Bone marrow failure": 12.71043646351251, "Cardiac failure": 2.4229411027673846, "Cardiomyopathy": 4.673806257893796, "Cytomegalovirus infection": 3.8908767942613873, "Cytopenia": 12.43871708505698, "Dermatitis exfoliative generalised": 5.151369433240756, "Diffuse large B-cell lymphoma recurrent": 49.93232641021019, "Disease progression": 4.188394116159946, "Disease recurrence": 2.5983683547370484, "Ejection fraction decreased": 3.183457138654644, "Febrile bone marrow aplasia": 57.595154942346966, "Febrile neutropenia": 20.043343567149268, "Full blood count decreased": 6.508644197216642, "Granulocyte count decreased": 37.55484819352679, "Granulocytopenia": 12.529442163376215, "Haemoglobin decreased": 2.2126612255206, "Hepatic cytolysis": 3.685245391831023, "Hepatic failure": 2.262710952945633, "Hepatitis B": 12.968281761654218, "Hepatitis B reactivation": 60.83092471733034, "Hyperpyrexia": 2.147906795748211, "Hypogammaglobulinaemia": 15.9027082667804, "Infection": 3.3525329448264727, "Infusion related reaction": 3.663189675439032, "Intentional product use issue": 4.341645693306297, "Interstitial lung disease": 6.6573274215883895, "Leukopenia": 10.523752922640986, "Lung disorder": 3.182178222229484, "Lung infiltration": 4.979017783483184, "Lymphoma": 4.692779402081943, "Lymphopenia": 8.472184485878547, "Mucosal inflammation": 4.347918998995172, "Multiple organ dysfunction syndrome": 2.6259913780759443, "Myelodysplastic syndrome": 5.493830037244657, "Myelosuppression": 48.20506914867611, "Neurotoxicity": 2.570163794905357, "Neutropenia": 10.243648404601656, "Neutrophil count decreased": 24.457928119942896, "Off label use": 2.260354664197113, "Pancytopenia": 8.996925630102426, "Platelet count decreased": 5.394000368332808, "Pneumocystis jirovecii pneumonia": 44.47282078568343, "Pneumonia": 3.0360029408749725, "Pneumonitis": 5.992381102178824, "Polyneuropathy": 7.078936670215466, "Progressive multifocal leukoencephalopathy": 89.70245689681086, "Pulmonary fibrosis": 5.333651518425477, "Respiratory tract infection": 2.403266910951043, "Sepsis": 3.1313110083870197, "Septic shock": 6.096958661345178, "Splenomegaly": 4.46286423994748, "Therapy partial responder": 4.146999215443456, "Thrombocytopenia": 4.222436013787468, "Tumour lysis syndrome": 5.392357082724299, "White blood cell count decreased": 18.83444965643559}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/703.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/703.json
index c5eb0261c97..832ce23e479 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/703.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/703.json
@@ -1 +1 @@
-{"Acne ": 3.865636637777612, "Acute polyneuropathy ": 18.550491100071337, "Amylase increased ": 2.317058432512847, "Anaplastic thyroid cancer ": 107.3960896031414, "Aspartate aminotransferase increased ": 2.023352671061999, "BRAF V600E mutation positive ": 111.732402846743, "Blindness ": 2.3150491481420974, "Blindness unilateral ": 2.274405063755457, "Blood albumin decreased ": 2.0701002513827924, "Blood calcium increased ": 2.577697898592423, "Blood creatine phosphokinase increased ": 6.735145285361813, "Blood lactate dehydrogenase increased ": 4.528790580533598, "Blood sodium decreased ": 2.3583757126130926, "Body temperature fluctuation ": 3.6736529871470096, "Brain neoplasm ": 11.375793718285378, "Brain neoplasm malignant ": 10.109197679668249, "Brain oedema ": 2.949462287465767, "C-reactive protein increased ": 3.3208199504652347, "Cardiac dysfunction ": 4.445948014653985, "Cardiomyopathy ": 3.503776402091129, "Cardiotoxicity ": 4.198907467459966, "Cell death ": 4.750027300384772, "Central nervous system lesion ": 11.914530964391025, "Cerebral disorder ": 2.381488841366805, "Cholangitis ": 4.815352855375657, "Cholestasis ": 4.683314590844747, "Colon cancer ": 2.1869595158399298, "Concomitant disease aggravated ": 3.572676712201394, "Concomitant disease progression ": 4.156892797559645, "Cutaneous sarcoidosis ": 15.40497449953932, "Death ": 5.00117615218492, "Dehydration ": 2.5350056158082994, "Dermatitis acneiform ": 17.89565332767047, "Disease progression ": 3.087920370927154, "Disseminated intravascular coagulation ": 2.3933374034148223, "Drug resistance ": 2.039196824706073, "Dry skin ": 3.153320323456388, "Dysphagia ": 2.48122294134146, "Ejection fraction abnormal ": 7.852849835832617, "Ejection fraction decreased ": 20.20283254462189, "Electrolyte imbalance ": 2.3677905708133062, "Encephalitis ": 2.754156714888123, "Erythema nodosum ": 21.6150175839276, "Eye disorder ": 2.170084256193644, "Fistula ": 3.3935040049406746, "General physical health deterioration ": 2.091430168229065, "Glioma ": 40.09074554321754, "Haemophagocytic lymphohistiocytosis ": 10.831384908967244, "Hepatic cytolysis ": 5.374563372540807, "Hepatic enzyme abnormal ": 2.606531854955437, "Hepatic lesion ": 3.5467034862827203, "Hepatitis ": 2.3985144491506976, "Hospice care ": 10.62283498436832, "Hospitalisation ": 2.455472691875326, "Hyperkeratosis ": 5.901501649971897, "Hyperpyrexia ": 4.269125840476595, "Hyperthermia ": 5.235849971520797, "Intestinal metastasis ": 21.687245922570543, "Intestinal perforation ": 3.960601882081469, "Iridocyclitis ": 3.4687485683041044, "Left ventricular dysfunction ": 2.192436164083205, "Lipase increased ": 3.830614050862919, "Liver disorder ": 2.676789269560892, "Liver function test increased ": 4.3246056087454114, "Lung adenocarcinoma ": 20.598264502973123, "Lung adenocarcinoma stage IV ": 47.45248308747861, "Lung neoplasm malignant ": 7.526168423111554, "Lung opacity ": 2.348278209407672, "Lymphocyte count decreased ": 3.5939439380494864, "Lymphoedema ": 3.579509541583436, "Macular oedema ": 4.772524171679895, "Malignant melanoma ": 64.03054324406182, "Malignant melanoma stage III ": 54.38052734536953, "Malignant melanoma stage IV ": 182.9944745065283, "Malignant neoplasm progression ": 21.414420371112428, "Malignant pleural effusion ": 9.124079053679669, "Melanocytic naevus ": 6.2175471404663565, "Melanoma recurrent ": 153.2119819876857, "Meningitis ": 2.324092423199864, "Metastases to adrenals ": 14.589020435136348, "Metastases to bone ": 9.656950559939787, "Metastases to bone marrow ": 22.585871291859128, "Metastases to central nervous system ": 82.53499261484295, "Metastases to kidney ": 23.562192365356974, "Metastases to liver ": 8.854432934553861, "Metastases to lung ": 14.76734707992742, "Metastases to lymph nodes ": 18.56970240604992, "Metastases to meninges ": 29.611906397240787, "Metastases to peritoneum ": 10.160155812159358, "Metastases to skin ": 34.301064275930294, "Metastases to spleen ": 22.585871291859128, "Metastasis ": 23.40704979929865, "Metastatic malignant melanoma ": 184.77386873663477, "Metastatic neoplasm ": 8.050283087717638, "Neoplasm ": 6.164231283551559, "Neutrophil count increased ": 3.194014718298717, "Non-small cell lung cancer ": 60.33700972276355, "Panniculitis ": 33.126236917580684, "Papilloedema ": 4.668197301718378, "Paronychia ": 3.3856004634457206, "Pneumonitis ": 3.779837005069093, "Polyneuropathy ": 2.351097961791508, "Product storage error ": 2.3554100402015554, "Product use in unapproved indication ": 5.589253280500519, "Protein total decreased ": 6.385838608670719, "Pulmonary mass ": 2.8087882270481943, "Pyrexia ": 3.2013586110704533, "Rash maculo-papular ": 2.3701106085002603, "Rash pustular ": 2.5146215323180927, "Recurrent cancer ": 14.22858399655825, "Retinal detachment ": 13.613952438710836, "Retinal vein occlusion ": 3.334135001803889, "Retinopathy ": 4.503406878502394, "Rhabdomyolysis ": 5.105861713078274, "Sarcoidosis ": 6.378226086359593, "Second primary malignancy ": 13.001679803304334, "Serous retinal detachment ": 37.03445642689844, "Skin cancer ": 2.330630129479124, "Skin lesion ": 2.5095559123046605, "Skin mass ": 3.649676029315638, "Skin toxicity ": 6.592807795233899, "Soft tissue sarcoma ": 58.41541493545706, "Squamous cell carcinoma ": 4.031246219712018, "Squamous cell carcinoma of skin ": 4.642306902251658, "Systemic inflammatory response syndrome ": 3.8748247051520415, "Therapy partial responder ": 2.9612114573624844, "Thyroid cancer ": 4.020398599762232, "Tubulointerstitial nephritis ": 2.205861343676207, "Uveitis ": 28.61920950305159, "Ventricular hypokinesia ": 4.581137954754486, "Vision blurred ": 2.208958882173063, "Visual acuity reduced ": 2.6044406314163044, "Visual impairment ": 3.3629855414440617, "Vitiligo ": 5.293387619662759, "Vitreous floaters ": 3.790070874074254, "Vogt-Koyanagi-Harada disease ": 29.88034123290466}
\ No newline at end of file
+{"Bone deformity": 25827.71185109847, "Graft complication": 69022.96824143936, "Transplant failure": 2971.3211525250745}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/704.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/704.json
index 542528dacb2..22825df00ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/704.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/704.json
@@ -1 +1 @@
-{"Abnormal dreams ": 7.342563868493295, "Acanthosis nigricans ": 233.18590181972124, "Accidental overdose ": 2.9186202413734117, "Aggression ": 4.994595058462952, "Agitation ": 3.7786953375078616, "Akathisia ": 4.804366691540161, "Alcoholism ": 33.60555518721919, "Appendicitis ": 7.715629821638753, "Appendicolith ": 23.776460596043343, "Ascites ": 2.2058623239586965, "Ataxia ": 4.14605254841787, "Bacterial infection ": 5.725215964894002, "Balance disorder ": 2.7099050798361635, "Behaviour disorder ": 4.079860722551242, "Blood cholesterol increased ": 2.141613949999428, "Blood prolactin increased ": 16.034255045091797, "Blood uric acid increased ": 8.691400737340238, "Cardiogenic shock ": 5.567231725404407, "Cardiomegaly ": 4.049634602542373, "Clavicle fracture ": 13.657087953362003, "Cognitive disorder ": 2.578429730851647, "Completed suicide ": 4.102613776946036, "Condition aggravated ": 2.0189659080269644, "Confusional state ": 2.133226659321523, "Constipation ": 2.9063461586420014, "Coordination abnormal ": 3.960724421100133, "Craniofacial fracture ": 28.912226248069658, "Delirium ": 3.2213387239742146, "Depressed level of consciousness ": 5.899756520856015, "Disorientation ": 3.252302476603136, "Distractibility ": 63.75139393289484, "Drug effective for unapproved indication ": 18.2963542504378, "Drug ineffective ": 2.430910298742029, "Drug ineffective for unapproved indication ": 7.517565391667079, "Drug interaction ": 2.2680173743331484, "Dry mouth ": 3.63572550439891, "Electrocardiogram QT prolonged ": 4.01986463270565, "Encephalopathy ": 2.2175173387228395, "Exercise tolerance decreased ": 4.117093602701224, "Exposure via breast milk ": 4.427784604890537, "Eyelid disorder ": 32.09815881046842, "Feeding disorder ": 3.120403623431516, "Feeling abnormal ": 3.2642761857077045, "Hallucination ": 3.950953057873376, "Hallucination, visual ": 4.104160179098392, "Hyperphosphataemia ": 32.79299335480949, "Hypersomnia ": 3.10700474972733, "Hyporeflexia ": 17.372796828632957, "Implant site infection ": 54.33093490658237, "Impulsive behaviour ": 19.403227347769885, "Incontinence ": 8.421779777177536, "Incorrect route of product administration ": 3.908664358311025, "Increased anteroposterior chest diameter ": 888.8504623211425, "Initial insomnia ": 10.813275526940268, "Insomnia ": 5.399498417560318, "Intentional overdose ": 25.59099691240368, "Intentional product misuse ": 4.24822352432333, "Intentional self-injury ": 106.75947978058886, "Irritability ": 2.756344921358165, "Joint range of motion decreased ": 4.003513871482803, "Judgement impaired ": 46.47530925376212, "Memory impairment ": 2.472631349724021, "Middle insomnia ": 46.09640544647803, "Myasthenia gravis ": 11.712335951291577, "Mydriasis ": 4.538616905507444, "Nightmare ": 16.003497676352573, "Obstructive sleep apnoea syndrome ": 13.340426662922388, "Overdose ": 2.4858812853342624, "Poisoning deliberate ": 6.507163746014482, "Poor quality sleep ": 8.041967535022787, "Product prescribing error ": 4.53425719078641, "Product use complaint ": 11.137790585126384, "Product use issue ": 2.4971311887244925, "Restless legs syndrome ": 2.562129463651672, "Rhonchi ": 36.05801041979489, "Sinus tachycardia ": 3.3746216081862626, "Skin disorder ": 2.2774617726156228, "Sleep apnoea syndrome ": 4.600863315791362, "Sleep disorder ": 7.625431222602592, "Somnolence ": 3.938401371397709, "Staphylococcal infection ": 2.246636484554279, "Suicide attempt ": 3.6527397080740527, "Suspected suicide ": 13.56006834994027, "Tardive dyskinesia ": 5.1147555069746025, "Therapeutic response decreased ": 4.485331955666212, "Toxicity to various agents ": 3.515408352386807, "Unevaluable event ": 5.301688634526713, "Vertigo ": 2.7152812272217086}
\ No newline at end of file
+{"Abdominal distension": 2.3216242172667703, "Ascites": 5.767481095904413, "Blood pressure decreased": 4.958650488734711, "Condition aggravated": 2.201489641561649, "Disease progression": 4.686597628794025, "Dyspnoea": 2.8167462000777057, "Epistaxis": 2.1320957314198825, "Fluid retention": 14.21990677363266, "Flushing": 4.186963455512954, "Haemorrhage subcutaneous": 19.77790066788693, "Hospitalisation": 4.62445461845534, "Hypervolaemia": 22.36448255179425, "Hypotension": 2.7063514454527025, "Hypoxia": 4.6371881765764265, "Internal haemorrhage": 31.65030092419465, "Nasal congestion": 4.338395642201544, "Oedema": 2.356028125288724, "Oedema peripheral": 3.5577758620082576, "Pain in jaw": 17.58210848648869, "Pericardial effusion": 9.219666598060046, "Peripheral swelling": 2.475609045230685, "Pleural effusion": 2.761403974233923, "Pneumonia": 2.935007309660792, "Post procedural haemorrhage": 25.2356376259538, "Product administration interrupted": 128.16032812845071, "Product use issue": 3.651372921561336, "Pulmonary arterial hypertension": 94.08349336414987, "Pulmonary hypertension": 34.204404234736465, "Pulmonary oedema": 11.202686820306052, "Right ventricular failure": 45.76092040542371, "Shock haemorrhagic": 19.145111727715264, "Syncope": 2.594464744556184, "Vascular device infection": 70.098781817112}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/705.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/705.json
index 6ce99989b3f..2331587778f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/705.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/705.json
@@ -1 +1 @@
-{"Acute graft versus host disease ": 83.38739046895434, "Acute graft versus host disease in intestine ": 64.2556300606548, "Acute myeloid leukaemia ": 9.619746996967937, "Adenovirus infection ": 71.32142619791969, "Ascites ": 3.146105082320292, "Bacteraemia ": 11.243229974855714, "Blood lactate dehydrogenase increased ": 4.079842593434381, "Cardiac failure ": 2.6894368319022948, "Cardiac failure congestive ": 2.3555939028127857, "Cardiomyopathy ": 4.745125392259742, "Chronic graft versus host disease ": 29.982214913207343, "Clostridium difficile colitis ": 8.944070256971859, "Clostridium difficile infection ": 7.037641393385618, "Colitis ": 2.8259187327942668, "Congenital aplasia ": 35.090598327140405, "Cystitis haemorrhagic ": 19.226264651319976, "Cytomegalovirus infection ": 11.41128180888587, "Cytomegalovirus infection reactivation ": 47.8561605807521, "Cytomegalovirus viraemia ": 34.398773285034835, "Drug ineffective for unapproved indication ": 6.739094433697799, "Febrile neutropenia ": 20.356831366201032, "Graft versus host disease in skin ": 37.25819953393263, "Haemophagocytic lymphohistiocytosis ": 22.19933142471585, "Hepatic cytolysis ": 2.902636152879413, "Hepatitis B reactivation ": 17.29619037851157, "Human herpesvirus 6 infection ": 85.5061207606328, "Hypervolaemia ": 12.324453460790409, "Hypoxia ": 3.2047242109656606, "Incorrect product administration duration ": 7.582793937870976, "Incorrect route of product administration ": 7.8080470551423025, "Iris atrophy ": 421.6769635803152, "Meningitis bacterial ": 54.39845061524957, "Mucosal inflammation ": 29.711473393345468, "Multiple organ dysfunction syndrome ": 7.120862460936055, "Myelodysplastic syndrome ": 18.383451752961964, "Neuropathy peripheral ": 3.499748097091025, "Neutropenia ": 5.420717624557706, "Neutropenic colitis ": 60.461402812124255, "Off label use ": 5.628906474723544, "Pancytopenia ": 7.517998685250997, "Plasma cell myeloma ": 17.811635782609535, "Pleural effusion ": 3.263682816630683, "Pneumonia fungal ": 27.487919385052948, "Product use in unapproved indication ": 4.750421211272868, "Pulmonary hypertension ": 6.042918517704777, "Respiratory failure ": 3.8326384878593664, "Retinal degeneration ": 124.06161256418096, "Sepsis ": 3.486285435335649, "Septic shock ": 7.366596790929221, "Staphylococcal infection ": 4.4873874708435535, "Stomatitis ": 5.63676359675866, "Thrombocytopenia ": 4.619457551631856, "Thrombotic microangiopathy ": 57.31363703392644, "Venoocclusive liver disease ": 92.23983851412775, "Viraemia ": 69.34003307326786}
\ No newline at end of file
+{"Acute kidney injury": 6.722012458829095, "Alanine aminotransferase increased": 3.978084233443691, "Altered state of consciousness": 5.262091304159024, "Anaphylactic reaction": 2.537572865930953, "Arrhythmia": 2.8696161635906186, "Aspartate aminotransferase increased": 8.81175030362971, "Blood alkaline phosphatase increased": 7.087680750848746, "Blood bilirubin increased": 6.658724086828021, "Blood lactate dehydrogenase increased": 10.213913209647584, "Blood lactic acid increased": 36.55478555195216, "Bradycardia foetal": 120.68706507158598, "Brain oedema": 20.95745080810684, "Cardiomyopathy": 16.42023319680405, "Disease progression": 3.117213923467475, "Disseminated intravascular coagulation": 8.881459736169768, "Drug ineffective": 2.689674941338813, "Foetal exposure during pregnancy": 3.0986054003782653, "Gamma-glutamyltransferase increased": 5.852570473464167, "Gastrointestinal disorder": 3.21685636765537, "Hepatic function abnormal": 5.592244400988305, "Hypokalaemia": 3.987309188677058, "Hyponatraemia": 4.607503304319176, "Hypotension": 2.207210256130236, "Intraocular pressure increased": 23.955267672282307, "Low birth weight baby": 14.254371169103957, "Metabolic acidosis": 7.857124829315548, "Myelosuppression": 22.981492639911885, "Nephropathy toxic": 19.14072067562964, "Palmar erythema": 133.11433221108734, "Platelet count decreased": 2.359311898350774, "Premature baby": 8.642685573808313, "Productive cough": 6.105726415386842, "Respiratory failure": 3.8669756186899074, "Rhabdomyolysis": 3.344413496146685, "Toxic epidermal necrolysis": 18.609102870062333, "White blood cell count decreased": 2.602616067140603, "Withdrawal hypertension": 843.2177030145225}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/706.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/706.json
index e1ca173a150..e064f29ab23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/706.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/706.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 7.068974726541299, "Aggression ": 15.149752151390114, "Agitation ": 9.545415854045324, "Altered state of consciousness ": 2.7660166607834733, "Anal incontinence ": 19.12740493642513, "Bradycardia ": 3.785151795454595, "Cardiac failure congestive ": 4.316877947941692, "Cerebrovascular accident ": 2.2962330139238576, "Cognitive disorder ": 3.068364178773824, "Confusional state ": 4.257124430776476, "Death ": 2.6635232559867386, "Dehydration ": 6.914077897941846, "Delirium ": 3.2981429538376545, "Dementia ": 8.75329344637986, "Dementia Alzheimer's type ": 18.50834631317517, "Dysphagia ": 2.5070819687613435, "Electrocardiogram QT prolonged ": 3.4258917463075487, "Fall ": 5.643826753833273, "Gait disturbance ": 3.2962636372886243, "Generalised tonic-clonic seizure ": 3.6486530029508257, "Hallucination ": 3.1470164016387168, "Hallucination, visual ": 5.846093479961975, "Hyponatraemia ": 2.622407360299305, "International normalised ratio increased ": 2.9070948684615576, "Lethargy ": 2.304281742699432, "Mental status changes ": 7.662391456502933, "Myoclonus ": 13.408167635860384, "Pneumonia aspiration ": 7.397405507474271, "Psychomotor hyperactivity ": 7.743706531478124, "Seizure ": 3.826773694336912, "Somnolence ": 2.310396567725583, "Syncope ": 2.218647255873932, "Transient ischaemic attack ": 4.296264435910807, "Treatment failure ": 2.2051036223215963, "Urinary incontinence ": 8.13235659100843, "Urinary tract infection ": 6.981592341460958}
\ No newline at end of file
+{"Back pain": 4.099885419004326, "Pneumonia": 4.133408481761401}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/707.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/707.json
index 677c3ac1458..0049b1a2341 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/707.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/707.json
@@ -1 +1 @@
-{"Erythema ": 3.484759199449172, "Febrile convulsion ": 44.19335513431783, "Injection site erythema ": 9.239081312419753, "Injection site swelling ": 6.5697580854623325, "Injection site warmth ": 9.453555700609286, "Pyrexia ": 4.403847995145165, "Rash ": 2.6228793186739803, "Urticaria ": 3.650229929913085}
\ No newline at end of file
+{"Abortion spontaneous": 2.48643431592856, "Acne": 2.630595617997154, "Alanine aminotransferase increased": 5.8159293774907415, "Alopecia": 6.551371109267973, "Aspartate aminotransferase increased": 5.053181073835853, "Breast cancer": 2.160357599162469, "COVID-19": 2.2855128701708574, "Central nervous system lesion": 10.425797244975628, "Diplopia": 2.2739132560226696, "Drug-induced liver injury": 2.161170468576438, "Expanded disability status scale score increased": 722.1823674853553, "Gamma-glutamyltransferase increased": 4.941962076264789, "Herpes simplex": 13.844738833364188, "Herpes zoster": 6.662502878490866, "Leukopenia": 2.3899524974578004, "Live birth": 5.828086139353221, "Lymphocyte count decreased": 327.4438447005385, "Lymphopenia": 244.83948294025197, "Maternal exposure before pregnancy": 35.08613985340896, "Maternal exposure timing unspecified": 18.50955092292672, "Multiple sclerosis": 77.4803866429658, "Multiple sclerosis relapse": 174.77523083919445, "Nasopharyngitis": 4.210710814717852, "Neutrophil count decreased": 2.4952865648934264, "Optic neuritis": 12.251022364824635, "Oral herpes": 18.49884000833011, "Product administration error": 2.092727515314078, "Sensory disturbance": 2.6646438776500165, "Upper respiratory tract infection": 4.732216427040466, "Urinary tract infection": 4.968816262189132, "White blood cell count decreased": 5.196812032200616}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/708.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/708.json
index b2252cc09bb..3cdd435c1a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/708.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/708.json
@@ -1 +1 @@
-{"Blood pressure decreased ": 2.278941399083135, "Bronchiolitis ": 52.96407928467741, "Cellulitis ": 14.478336598434163, "Cyanosis ": 2.1835449777317977, "Dyskinesia ": 3.2774674902731102, "Eating disorder ": 6.579215815227368, "Erythema ": 5.466266583215194, "Extensive swelling of vaccinated limb ": 15.1349492679496, "Eye movement disorder ": 10.952024416446344, "Febrile convulsion ": 4.8867043759076685, "Flushing ": 4.363958105086375, "Guillain-Barre syndrome ": 5.002027772462974, "Head injury ": 5.515812438376587, "Heart rate decreased ": 3.1463137600313003, "Hyperpyrexia ": 9.755469328811758, "Hypotonia ": 4.567090848444231, "Induration ": 23.65567321618604, "Inflammation ": 8.721181010352149, "Injected limb mobility decreased ": 9.48919609341109, "Injection site erythema ": 5.153677110621563, "Injection site induration ": 7.687753755446627, "Injection site oedema ": 17.455522973032824, "Injection site pruritus ": 2.2141612325441598, "Injection site reaction ": 2.547688211026684, "Irritability ": 3.849798913321313, "Local reaction ": 25.032541326903686, "Localised oedema ": 5.199834042457992, "Loss of consciousness ": 3.8460747118948846, "Lymphadenitis ": 4.367716418813148, "Meningitis meningococcal ": 135.67257430230964, "Meningococcal sepsis ": 232.4328799216312, "Muscle rigidity ": 7.146836995226273, "Neck pain ": 2.168382562315345, "Oedema ": 3.577665911248734, "Pallor ": 10.726832060595894, "Peripheral swelling ": 2.255393630937274, "Petechiae ": 3.684071865941208, "Pharyngeal swelling ": 2.147651021907916, "Pharyngitis ": 4.874829537603974, "Photophobia ": 5.293169380409728, "Presyncope ": 5.491821028525964, "Product preparation issue ": 8.599709621853313, "Seizure like phenomena ": 37.59575455994912, "Skin warm ": 12.859470211311724, "Swelling ": 2.494978695153696, "Syncope ": 7.617114594183518, "Syringe issue ": 17.302810662372657, "Throat tightness ": 2.4494990278266755, "Tonic clonic movements ": 18.47153807110239, "Type III immune complex mediated reaction ": 42.5449656612914, "Unresponsive to stimuli ": 3.3443448879763653, "Upper respiratory tract infection ": 2.9832453852425265, "Urticaria ": 2.128916200330295, "Vaccination site cellulitis ": 149.46037768367236, "Vaccination site erythema ": 10.109563158396892, "Vaccination site induration ": 38.6015465631628, "Vaccination site inflammation ": 8.020744994118138, "Vaccination site joint swelling ": 65.08829983941715, "Vaccination site oedema ": 47.43242298537725, "Vaccination site pain ": 2.1860909693921133, "Vaccination site pruritus ": 2.9704376801071093, "Vaccination site reaction ": 4.241963285669499, "Vaccination site swelling ": 5.737976516164305, "Vaccination site warmth ": 15.74673184308442, "Viral infection ": 3.609901953220176}
\ No newline at end of file
+{"Drug ineffective": 2.3483443041642773}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/709.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/709.json
index 8ce2ad860e9..a8590b38a93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/709.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/709.json
@@ -1 +1 @@
-{"Abnormal sensation in eye ": 11.515727471543787, "Accident ": 3.301851753700737, "Addison's disease ": 45.041835121308175, "Adrenal insufficiency ": 4.271972979015433, "Adverse drug reaction ": 6.003095183699547, "Airway remodelling ": 95.16366625481815, "Allergic sinusitis ": 85.20755279076121, "Aortic stenosis ": 6.979657621364519, "Aortic valve disease ": 8.870624782641633, "Appetite disorder ": 6.230200995265609, "Aspergillus infection ": 5.681323653147612, "Asphyxia ": 3.860338665188433, "Asplenia ": 184.3753193869933, "Asthma ": 32.75679986943822, "Asthmatic crisis ": 25.428405385345503, "Atelectasis ": 2.044985143358633, "Atrial septal defect ": 2.81266688987522, "Bacterial infection ": 8.887497859691383, "Blood immunoglobulin E increased ": 19.54803941744244, "Blood immunoglobulin M decreased ": 66.63538729671635, "Blood pressure abnormal ": 2.323688576289395, "Blood pressure increased ": 3.0013009219955125, "Blood pressure systolic decreased ": 2.070709567079417, "Blood test abnormal ": 5.704911127696822, "Breast disorder ": 22.839437839806884, "Breast neoplasm ": 13.89880765352929, "Breast operation ": 24.34012161284911, "Breath sounds abnormal ": 13.195933817245791, "Bronchial hyperreactivity ": 6.580119315673018, "Bronchial obstruction ": 97.43421844921116, "Bronchial secretion retention ": 11.529871446452535, "Bronchial wall thickening ": 7.4445153590315325, "Bronchiectasis ": 8.809644625387556, "Bronchiolitis ": 2.0523245159007684, "Bronchitis ": 4.066870378386263, "Bronchitis chronic ": 4.891488166384924, "Bronchopulmonary aspergillosis allergic ": 15.12851016024404, "CFTR gene mutation ": 2174.127046778093, "Cardiac ablation ": 14.567507667419768, "Cardiac murmur ": 3.9450835934059305, "Cataract ": 2.144824758490625, "Cataract operation ": 3.76089216217782, "Chemotherapy ": 5.6393262222795775, "Chest X-ray abnormal ": 3.871594276572379, "Chest discomfort ": 3.279275105718388, "Choking ": 5.197176735522355, "Chronic obstructive pulmonary disease ": 5.36357849397271, "Coronavirus infection ": 5.158658257363304, "Coronavirus test positive ": 12.13701612054356, "Cough ": 5.353699635547603, "Crepitations ": 15.738117692230386, "Cushing's syndrome ": 4.073352902390662, "Cushingoid ": 13.0694424116693, "Cyst ": 3.0854002127379943, "Decreased activity ": 12.563517873260036, "Depressed mood ": 2.129759083012056, "Depressive symptom ": 5.880628147294402, "Dermatitis allergic ": 5.754657507771337, "Drug hypersensitivity ": 2.3159257202602643, "Dysphonia ": 2.273216850496192, "Dyspnoea ": 5.089248050951322, "Dyspnoea exertional ": 12.665602138356224, "Ear disorder ": 5.352281985808756, "Ear infection ": 7.183560183295332, "Eczema ": 6.206163741687442, "Emphysema ": 6.745396259618143, "Eosinophil count abnormal ": 237.43153632357004, "Eosinophil count decreased ": 21.94766037833736, "Eosinophil count increased ": 15.156526961053652, "Eosinophilia ": 2.253313289091563, "Eosinophilic bronchitis ": 58.02955460244365, "Eosinophilic granulomatosis with polyangiitis ": 5.617161210626048, "Escherichia infection ": 2.8169032388506934, "Exposure to SARS-CoV-2 ": 46.01003521532816, "Extra dose administered ": 2.6112144004334747, "Eye irritation ": 2.1540413066700155, "Eye pruritus ": 8.67638608415968, "FEV1/FVC ratio decreased ": 50.55608645688515, "Feeding disorder ": 5.228702119655191, "Flank pain ": 2.9250859050954965, "Forced expiratory volume abnormal ": 53.1521762333382, "Forced expiratory volume decreased ": 5.025501050625416, "Frustration tolerance decreased ": 2.8992863653286145, "Full blood count abnormal ": 30.025746739401605, "Fungal infection ": 5.48827309614363, "Gait inability ": 2.3049845961166917, "Gastrointestinal obstruction ": 15.247776576126975, "Gastrooesophageal reflux disease ": 2.4684664846831663, "General physical condition abnormal ": 3.0153835563807547, "Glaucoma ": 8.813482547086736, "Granuloma ": 10.26227057793576, "Haemoglobin abnormal ": 4.503253390975902, "Head discomfort ": 2.147052489257701, "Heart sounds ": 95.0641364361324, "Hepatic cyst ": 7.429126593250801, "Hospitalisation ": 4.224066325036662, "Hyperaemia ": 9.012246343986456, "Ill-defined disorder ": 2.541509423199464, "Immunoglobulins increased ": 48.167893669448745, "Inappropriate schedule of product administration ": 4.133627515147525, "Increased bronchial secretion ": 21.032245913482697, "Infection ": 3.690326293272443, "Influenza ": 2.9302143865762544, "Intentional dose omission ": 7.077536511994595, "Intestinal haemorrhage ": 5.839601293681031, "Intestinal stent insertion ": 581.5570786562088, "Kyphosis ": 11.514333265814438, "Laboratory test abnormal ": 5.055496838437614, "Labyrinthitis ": 9.844129040870063, "Lip pruritus ": 18.598154005894145, "Lipohypertrophy ": 10.58935036183204, "Loss of personal independence in daily activities ": 25.248698951458405, "Lower respiratory tract congestion ": 12.116768442813347, "Lower respiratory tract infection ": 8.454618242478228, "Lumbar vertebral fracture ": 3.095252352220609, "Lung diffusion disorder ": 45.47689497459437, "Lung hyperinflation ": 15.38863402841734, "Lung opacity ": 3.523286704059034, "Lymphadenopathy mediastinal ": 9.329706973203116, "Macrocytosis ": 10.842457184564276, "Magnetic resonance imaging heart ": 108.46702368418488, "Middle insomnia ": 12.0458594243768, "Mite allergy ": 15.757386825678555, "Monocyte count increased ": 3.7617063447774512, "Mucosal disorder ": 4.484793931896532, "Multiple allergies ": 17.889475495498083, "Musculoskeletal chest pain ": 8.132743216889573, "Mycobacterium avium complex infection ": 17.91529315822425, "Nasal congestion ": 7.530938140948781, "Nasal discharge discolouration ": 148.91171148216262, "Nasal disorder ": 5.790630077018108, "Nasal obstruction ": 5.129680157424341, "Nasal polyps ": 5.169910165821498, "Nasopharyngitis ": 5.766419129305357, "Nerve compression ": 4.549972307157433, "Neurosensory hypoacusis ": 31.64167749954049, "Obstruction ": 13.535249459310538, "Obstructive airways disorder ": 33.70875074627306, "Ocular discomfort ": 14.676213678293555, "Ocular hyperaemia ": 6.117970676065559, "Oesophageal polyp ": 131.71038952237984, "Oropharyngeal pain ": 2.3394195407731893, "Otitis media ": 2.5308737787287137, "Oxygen saturation abnormal ": 4.304199607577753, "Oxygen saturation decreased ": 3.1686839029537186, "Pancreatitis relapsing ": 25.943104994050174, "Perfume sensitivity ": 41.02014716286871, "Pneumonia ": 5.071873202237676, "Pneumonia respiratory syncytial viral ": 30.23540190848667, "Polymyalgia rheumatica ": 2.648258949268122, "Polyp ": 22.05448892182321, "Post-traumatic stress disorder ": 6.672711702534168, "Presbyacusis ": 26.942616045164947, "Product administration error ": 2.2545662490435574, "Product dose omission issue ": 4.352064644506198, "Productive cough ": 20.413055348865477, "Prolonged expiration ": 64.75583166018866, "Prostatic disorder ": 5.523539286681516, "Pulmonary congestion ": 2.0375779091566675, "Pulmonary eosinophilia ": 19.24550781904297, "Pulmonary function test abnormal ": 10.90099661436422, "Pulmonary mass ": 9.745079026609538, "Rales ": 21.582549911627225, "Rectal cancer ": 8.737845000337044, "Red blood cell count increased ": 9.152397548808349, "Reflux laryngitis ": 56.16086402178681, "Respiration abnormal ": 5.897630707723087, "Respiratory disorder ": 4.641953314301232, "Respiratory gas exchange disorder ": 39.55302457394728, "Respiratory rate increased ": 2.1421562914260424, "Respiratory symptom ": 10.737940061205052, "Respiratory tract congestion ": 14.855088238881269, "Respiratory tract infection ": 6.46393081707223, "Reversible airways obstruction ": 165.91041215958182, "Rhinitis ": 7.544861199545633, "Rhinorrhoea ": 5.1193576864398125, "Right ventricular dysfunction ": 11.446924330030573, "Sarcoidosis ": 3.1972066583225103, "Seasonal allergy ": 24.76085452096457, "Secretion discharge ": 6.842564032850573, "Sense of oppression ": 3.977383201998281, "Sinus congestion ": 16.476295228475948, "Sinus disorder ": 5.434459252441535, "Sinusitis ": 5.035211994635872, "Skin atrophy ": 6.603647336083183, "Skin fragility ": 53.02451967239688, "Skin laceration ": 3.9734039957580776, "Sleep apnoea syndrome ": 3.725102838325321, "Sleep disorder due to a general medical condition ": 93.50031023286404, "Sneezing ": 2.7960590243849404, "Snoring ": 8.745649561522661, "Social problem ": 15.03837522639011, "Spirometry abnormal ": 25.059637481166327, "Sputum abnormal ": 33.3962747168102, "Sputum culture positive ": 33.17711366969584, "Sputum discoloured ": 73.55891724973631, "Sputum increased ": 35.13072486842116, "Sputum purulent ": 52.82226378092133, "Stent placement ": 2.55283369972592, "Stress ": 4.572449274301095, "Symptom recurrence ": 15.577538721492443, "Therapeutic product effect incomplete ": 31.127464054027783, "Therapeutic response decreased ": 2.1503065250481885, "Therapy cessation ": 2.815014678550443, "Throat clearing ": 4.860631988550817, "Tooth extraction ": 2.3330810237935387, "Total lung capacity decreased ": 27.465068316865075, "Transient ischaemic attack ": 2.045139305106808, "Unevaluable event ": 2.07475202496778, "Upper respiratory tract infection ": 5.223758101595506, "Upper-airway cough syndrome ": 21.72670457495433, "Urethritis ": 13.163009888939, "Urine abnormality ": 3.943569849298, "Vaccination site haemorrhage ": 18.417433129844696, "Viral infection ": 7.512845545202341, "Vital capacity decreased ": 33.828378393225535, "Wheelchair user ": 16.213593498519252, "Wheezing ": 42.67550950733181, "Wound infection ": 6.128456544084177}
\ No newline at end of file
+{"Abdominal discomfort": 8.203096816302743, "Abdominal pain lower": 53.635991976801535, "Contusion": 12.902804217982728, "Eye haemorrhage": 77.41697412515178, "Hypoaesthesia": 7.042494970994402, "Multiple sclerosis": 92.35270030804791, "Musculoskeletal stiffness": 12.858548505148864, "Vomiting": 2.204040016538016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/71.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/71.json
index afe0b78e2c5..15b0a740f0b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/71.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/71.json
@@ -1 +1 @@
-{"Depression ": 5.2904288142913645, "Drug resistance ": 27.7725328581426, "Hepatic enzyme increased ": 8.899852357985706, "Lipodystrophy acquired ": 147.90997635781167, "Non-alcoholic steatohepatitis ": 683.7381828613328}
\ No newline at end of file
+{"Balance disorder": 34.13441854842257, "Blood calcium decreased": 264.26574021931714, "Cognitive disorder": 63.71014152609484, "Constipation": 17.15046578978299, "Creatinine renal clearance decreased": 334.2392335047507, "Creatinine renal clearance increased": 909.540138114541, "Depressed level of consciousness": 44.3927610565479, "Dyspnoea": 3.196216448416595, "Fall": 11.897686322053977, "Hypotension": 11.708290053400296, "Mobility decreased": 42.02602056409437, "Multiple drug therapy": 1266.7035623438549, "Orthostatic hypotension": 100.3585679176368, "Pain": 3.943691073472674, "Product use in unapproved indication": 3.1538655938880025, "Renal function test abnormal": 236.61149787421976, "Sedation": 111.98748844841803, "Sedation complication": 362.1595705485053, "Toxicity to various agents": 16.72914899626805}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/710.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/710.json
index 3ef63e8d875..0c6731623ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/710.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/710.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 7.297124029268871, "Acute lymphocytic leukaemia recurrent ": 18.277856129889, "Acute myeloid leukaemia ": 13.298400265273283, "Agranulocytosis ": 4.254285438140775, "Alanine aminotransferase increased ": 3.270414669057343, "Amylase increased ": 7.198305564678553, "Anaemia ": 2.068082146117088, "Bacteraemia ": 10.45845608051359, "Blood bilirubin increased ": 3.315554842848549, "Bone marrow failure ": 5.531587294169802, "Cholestasis ": 2.5692758690732536, "Colitis ulcerative ": 2.265380030791519, "Crohn's disease ": 6.492516271567511, "Cytomegalovirus chorioretinitis ": 56.61821124982143, "Cytomegalovirus infection ": 16.161915598474675, "Cytopenia ": 7.559227504848666, "Diarrhoea haemorrhagic ": 9.609224261998609, "Disease recurrence ": 5.336959603490218, "Drug-induced liver injury ": 4.53203541926135, "Exposure during pregnancy ": 2.5027456578084637, "Febrile neutropenia ": 48.199582006460346, "Haemoglobin decreased ": 2.8542490886318124, "Haemophagocytic lymphohistiocytosis ": 15.926663805086678, "Hepatic function abnormal ": 2.0764371786360987, "Hepatitis ": 2.245985655132154, "Hepatosplenic T-cell lymphoma ": 283.7303273000464, "Hepatotoxicity ": 11.327954826698743, "Hyperbilirubinaemia ": 5.766278859221334, "Jaundice ": 4.162901294072843, "Langerhans' cell histiocytosis ": 311.60788927957253, "Leukaemia recurrent ": 32.29158903987639, "Leukopenia ": 10.909300572773898, "Lipase increased ": 7.899123843845635, "Liver function test abnormal ": 4.525445890859405, "Lymphopenia ": 6.794389196299509, "Mental disorder ": 3.328053703309068, "Mouth ulceration ": 3.627643433409321, "Mucosal inflammation ": 5.434794374256518, "Myelodysplastic syndrome ": 4.931076439286908, "Myelosuppression ": 32.64145417093603, "Neutropenia ": 6.160829391152121, "Neutrophil count decreased ": 10.69729267415639, "Nodular regenerative hyperplasia ": 137.24568877727535, "Off label use ": 3.7911385634314994, "Pallor ": 2.6016607346539904, "Pancreatitis ": 6.481835431929405, "Pancreatitis acute ": 6.95560824244525, "Pancreatitis necrotising ": 25.499085566225485, "Pancytopenia ": 15.927044981458106, "Platelet count decreased ": 4.643078354051314, "Pneumocystis jirovecii pneumonia ": 5.673383651283134, "Product use issue ": 2.1919666233671906, "Sepsis ": 2.991423231014356, "Splenomegaly ": 4.737562928803312, "Stomatitis ": 2.3046891723574965, "Thrombocytopenia ": 2.2857107949690647, "Upper respiratory tract infection ": 3.0415188096971173, "Viral infection ": 4.01416988430293, "White blood cell count decreased ": 8.45404145884898}
\ No newline at end of file
+{"Cardiomyopathy": 117.02464658818084}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/711.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/711.json
index 8442ede63aa..d2d52568f5d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/711.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/711.json
@@ -1 +1 @@
-{"Herpes zoster ": 17.952416527121674, "Vaccination failure ": 3.301923646555068}
\ No newline at end of file
+{"Acne": 3.863900678819783, "Acute polyneuropathy": 18.542161688061253, "Amylase increased": 2.316018006012534, "Anaplastic thyroid cancer": 107.34786695611486, "Aspartate aminotransferase increased": 2.02244397441423, "BRAF V600E mutation positive": 111.68223401325032, "Blindness": 2.314009516060558, "Blindness unilateral": 2.2733837825056304, "Blood albumin decreased": 2.0691707348025967, "Blood calcium increased": 2.576540460546397, "Blood creatine phosphokinase increased": 6.732120148699925, "Blood lactate dehydrogenase increased": 4.526756779370326, "Blood sodium decreased": 2.35731671167896, "Body temperature fluctuation": 3.67200346639987, "Brain neoplasm": 11.370685293800545, "Brain neoplasm malignant": 10.104658395365847, "Brain oedema": 2.9481378578518056, "C-reactive protein increased": 3.319328529838811, "Cardiac dysfunction": 4.443951704125717, "Cardiomyopathy": 3.502203014324529, "Cardiotoxicity": 4.197022043627395, "Cell death": 4.74789447301703, "Central nervous system lesion": 11.909180653404128, "Cerebral disorder": 2.38041950983578, "Cholangitis": 4.813190639270961, "Cholestasis": 4.681211367798367, "Colon cancer": 2.185977507513396, "Concomitant disease aggravated": 3.571072465374731, "Concomitant disease progression": 4.15502629558916, "Cutaneous sarcoidosis": 15.398057463042177, "Death": 4.9989285773258905, "Dehydration": 2.533731390580068, "Dermatitis acneiform": 17.887616917140672, "Disease progression": 3.0865334237674493, "Disseminated intravascular coagulation": 2.3922626869719816, "Drug resistance": 2.038281106331965, "Dry skin": 3.151904218956207, "Dysphagia": 2.480108567082398, "Ejection fraction abnormal": 7.849323766583291, "Ejection fraction decreased": 20.19375858093819, "Electrolyte imbalance": 2.3667273641171405, "Encephalitis": 2.752920009748525, "Erythema nodosum": 21.60531072498026, "Eye disorder": 2.169109793312289, "Fistula": 3.3919802748936925, "General physical health deterioration": 2.0904908754628857, "Glioma": 40.072743996917694, "Haemophagocytic lymphohistiocytosis": 10.826520826364264, "Hepatic cytolysis": 5.372149591942083, "Hepatic enzyme abnormal": 2.605361486140992, "Hepatic lesion": 3.545110952534604, "Hepatitis": 2.3974373304170253, "Hospice care": 10.618065064286146, "Hospitalisation": 2.4543699356278124, "Hyperkeratosis": 5.89885166852538, "Hyperpyrexia": 4.2672086464234935, "Hyperthermia": 5.233498759087492, "Intestinal metastasis": 21.677508070145265, "Intestinal perforation": 3.958823432305798, "Iridocyclitis": 3.4671910377040467, "Left ventricular dysfunction": 2.191451720599213, "Lipase increased": 3.8288939181089487, "Liver disorder": 2.675587149184285, "Liver function test increased": 4.322663492222763, "Lung adenocarcinoma": 20.58901489986512, "Lung adenocarcinoma stage IV": 47.43117599142408, "Lung neoplasm malignant": 7.522788296753413, "Lung opacity": 2.347223800017273, "Lymphocyte count decreased": 3.592330114879607, "Lymphoedema": 3.577902232297576, "Macular oedema": 4.7703811952517565, "Malignant melanoma": 64.0017770057119, "Malignant melanoma stage III": 54.35610889563307, "Malignant melanoma stage IV": 182.91229607400115, "Malignant neoplasm progression": 21.404794520340413, "Malignant pleural effusion": 9.119982180505314, "Melanocytic naevus": 6.214755350681995, "Melanoma recurrent": 153.1431817580438, "Meningitis": 2.3230488546159225, "Metastases to adrenals": 14.582469653935346, "Metastases to bone": 9.652613631305078, "Metastases to bone marrow": 22.575729946073945, "Metastases to central nervous system": 82.49791418944575, "Metastases to kidney": 23.551612640014262, "Metastases to liver": 8.850456318573222, "Metastases to lung": 14.760714822510034, "Metastases to lymph nodes": 18.561362913298435, "Metastases to meninges": 29.598609115839785, "Metastases to peritoneum": 10.155593579182266, "Metastases to skin": 34.28566162207151, "Metastases to spleen": 22.575729946073945, "Metastasis": 23.39653800051764, "Metastatic malignant melanoma": 184.69087549226515, "Metastatic neoplasm": 8.046668306986133, "Neoplasm": 6.161463275336881, "Neutrophil count increased": 3.19258052973548, "Non-small cell lung cancer": 60.309910668213085, "Panniculitis": 33.111360553567046, "Papilloedema": 4.666101138623208, "Paronychia": 3.384080282196391, "Pneumonitis": 3.778139555715681, "Polyneuropathy": 2.3500422255022744, "Product storage error": 2.354352351797106, "Product use in unapproved indication": 5.586566709570676, "Protein total decreased": 6.382971216404859, "Pulmonary mass": 2.807526969748478, "Pyrexia": 3.202486785054562, "Rash maculo-papular": 2.369046197509186, "Rash pustular": 2.5134924073567397, "Recurrent cancer": 14.22219484898548, "Retinal detachment": 13.607838636615742, "Retinal vein occlusion": 3.3326379020841856, "Retinopathy": 4.501384711294162, "Rhabdomyolysis": 5.103568455256867, "Sarcoidosis": 6.375361993792552, "Second primary malignancy": 12.995840973245516, "Serous retinal detachment": 37.017826416601885, "Skin cancer": 2.329583616851272, "Skin lesion": 2.5084289753399736, "Skin mass": 3.648037225245433, "Skin toxicity": 6.580342247647291, "Soft tissue sarcoma": 58.389183700585455, "Squamous cell carcinoma": 4.029436060528416, "Squamous cell carcinoma of skin": 4.640222404996487, "Systemic inflammatory response syndrome": 3.8730848471667856, "Therapy partial responder": 2.9598817827229364, "Thyroid cancer": 4.018593311506203, "Tubulointerstitial nephritis": 2.204870821297397, "Uveitis": 28.60635493784832, "Ventricular hypokinesia": 4.579080932440624, "Vision blurred": 2.207966767052591, "Visual acuity reduced": 2.6032711069643195, "Visual impairment": 3.361474941765595, "Vitiligo": 5.291010753912912, "Vitreous floaters": 3.788368993071226, "Vogt-Koyanagi-Harada disease": 29.866924239522238}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/712.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/712.json
index dc3fcbdcaa1..aa4e185505b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/712.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/712.json
@@ -1 +1 @@
-{"Cerebral haematoma ": 393.1247726909989, "Cerebral haemorrhage ": 179.7815841222343}
\ No newline at end of file
+{"Abnormal dreams": 7.340968484047119, "Acanthosis nigricans": 233.1352449824683, "Accidental overdose": 2.917986137475613, "Aggression": 4.9935096143109, "Agitation": 3.777874100117832, "Akathisia": 4.803322928830559, "Alcoholism": 33.59825451496787, "Appendicitis": 7.713953513148684, "Appendicolith": 23.77129496537472, "Ascites": 2.205383080995745, "Ataxia": 4.145151782313103, "Bacterial infection": 5.7239721120051215, "Balance disorder": 2.709316206095059, "Behaviour disorder": 4.078974386039061, "Blood cholesterol increased": 2.1411486427712, "Blood prolactin increased": 16.03077160976915, "Blood uric acid increased": 8.689512455766716, "Cardiogenic shock": 5.566022150973088, "Cardiomegaly": 4.048754845800217, "Clavicle fracture": 13.654121089811504, "Cognitive disorder": 2.577869516943856, "Completed suicide": 4.101722038191308, "Condition aggravated": 2.018527057011901, "Confusional state": 2.132762983780764, "Constipation": 2.9057144348795974, "Coordination abnormal": 3.959863966550817, "Craniofacial fracture": 28.90594445613771, "Delirium": 3.220638765757424, "Depressed level of consciousness": 5.898474269437994, "Disorientation": 3.251595783394677, "Distractibility": 63.73754424672382, "Drug effective for unapproved indication": 18.292379266965742, "Drug ineffective": 2.430363478814352, "Drug ineffective for unapproved indication": 7.515931884232184, "Drug interaction": 2.267524373400216, "Dry mouth": 3.63493535075898, "Electrocardiogram QT prolonged": 4.018991099445175, "Encephalopathy": 2.217035583181499, "Exercise tolerance decreased": 4.116199177470562, "Exposure via breast milk": 4.426822712663907, "Eyelid disorder": 32.09118561280188, "Feeding disorder": 3.119725725784809, "Feeling abnormal": 3.263503756710313, "Hallucination": 3.950094370718908, "Hallucination, visual": 4.103268460571258, "Hyperphosphataemia": 32.785868816720985, "Hypersomnia": 3.1063297437196384, "Hyporeflexia": 17.36902265085328, "Implant site infection": 54.31913211775271, "Impulsive behaviour": 19.39901206726316, "Incontinence": 8.419950096987858, "Incorrect route of product administration": 3.9078151352585913, "Increased anteroposterior chest diameter": 888.6573787653879, "Initial insomnia": 10.810926250453456, "Insomnia": 5.398324099387916, "Intentional overdose": 25.5854285212531, "Intentional product misuse": 4.247300242771841, "Intentional self-injury": 106.73625453350212, "Irritability": 2.755614307086228, "Joint range of motion decreased": 4.002644121068477, "Judgement impaired": 46.46521269425487, "Memory impairment": 2.472094022652299, "Middle insomnia": 46.08638523006889, "Myasthenia gravis": 11.70979131417658, "Mydriasis": 4.537630877683262, "Nightmare": 16.000018673218584, "Obstructive sleep apnoea syndrome": 13.337528545280822, "Overdose": 2.4853409892807115, "Poisoning deliberate": 6.505750152874651, "Poor quality sleep": 8.040220079294649, "Product prescribing error": 4.5332720838836975, "Product use complaint": 11.135370903257998, "Product use issue": 2.496588515332965, "Restless legs syndrome": 2.561572875498012, "Rhonchi": 36.050176963731566, "Sinus tachycardia": 3.3738884825227378, "Skin disorder": 2.276966980537488, "Sleep apnoea syndrome": 4.597825087607563, "Sleep disorder": 7.623773498407836, "Somnolence": 3.9375015009916665, "Staphylococcal infection": 2.246148424969404, "Suicide attempt": 3.6519458450533886, "Suspected suicide": 13.557122236386848, "Tardive dyskinesia": 5.113644377231088, "Therapeutic response decreased": 4.484357328094697, "Toxicity to various agents": 3.514644134928444, "Unevaluable event": 5.3005367013444245, "Vertigo": 2.7146910925770213}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/713.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/713.json
index 4a683df7875..69a51824cb4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/713.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/713.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.2104922963478755, "Acute kidney injury ": 2.232717283082681, "Altered state of consciousness ": 6.941119395343088, "Anuria ": 10.079941522585113, "Appetite disorder ": 12.024749024022574, "Blister ": 18.133870710081453, "Blister rupture ": 449.7576783969333, "Blood creatine phosphokinase increased ": 2.1680684738045417, "Blood glucose increased ": 4.824011318469732, "Blood ketone body increased ": 45.93996937265378, "Blood lactic acid increased ": 12.380623713043832, "Blood pressure systolic increased ": 12.905443169736596, "Blood thyroid stimulating hormone increased ": 22.850829720844008, "Cardiac failure ": 2.63676534816854, "Cerebral infarction ": 3.3476222809366543, "Cognitive disorder ": 4.855232540577087, "Concomitant disease aggravated ": 26.42028381085322, "Concomitant disease progression ": 22.234402459292085, "Constipation ": 2.742269283501876, "Decreased appetite ": 3.022270945845272, "Dehydration ": 5.848554704931077, "Dementia ": 5.124658783209105, "Dermatitis ": 6.074622979168644, "Dermatitis bullous ": 9.986265913816217, "Diabetes mellitus inadequate control ": 46.19856862577995, "Diabetic nephropathy ": 28.19550425164873, "Dyslipidaemia ": 36.77333980987071, "Eczema ": 4.663305494999279, "Eosinophilia ": 3.779736757670315, "Erythema ": 2.946051592165255, "Food allergy ": 21.643411920315177, "Gastrooesophageal reflux disease ": 3.853063278370715, "Glomerular filtration rate decreased ": 3.82382876781628, "Glycosylated haemoglobin increased ": 29.01814730792279, "Haematocrit decreased ": 10.207662634458815, "Haemoglobin decreased ": 2.2575391355425576, "Hepatic function abnormal ": 2.63039415612761, "Hepatic steatosis ": 16.351750291338135, "Hyperglycaemia ": 5.702916967877856, "Hyperkalaemia ": 3.837990250128751, "Hypoglycaemia ": 5.966320988171951, "Hypophagia ": 5.958762500351369, "Hypothyroidism ": 3.5956081282438097, "Inflammation ": 3.74834891863175, "Intercepted product prescribing error ": 103.4576834254992, "Lactic acidosis ": 37.51443785708738, "Lymphocyte count decreased ": 19.43411798016228, "Metabolic acidosis ": 4.27529891119734, "Metastases to liver ": 3.755512816027257, "Mucosal disorder ": 28.135875336172823, "Neutrophil count decreased ": 3.0516477482557485, "Pancreatic carcinoma ": 4.979488155907248, "Pancreatitis acute ": 4.618796183190683, "Papule ": 4.364007459109607, "Pemphigoid ": 186.7322681135001, "Physical deconditioning ": 29.53439335498188, "Prostate cancer ": 10.83510027665936, "Proteinuria ": 7.345176640142861, "Red blood cell count decreased ": 7.5991257544354385, "Renal impairment ": 6.583843222247448, "Respiratory syncytial virus infection ": 11.58714688475367, "Rhabdomyolysis ": 2.844466851094132, "SARS-CoV-2 test positive ": 3.699339718112823, "Shock ": 3.327023834886204, "Skin erosion ": 57.99069923596083, "Skin exfoliation ": 9.748322001508733, "Splenomegaly ": 15.579364799229324, "Tachypnoea ": 2.9277723342477344, "Tonsil cancer ": 142.19237395618146, "Treatment noncompliance ": 3.459413085796258, "Tuberculosis ": 20.661724594586023, "Type 2 diabetes mellitus ": 13.024930574956072, "Vitamin D deficiency ": 12.499801468984623, "Weight decreased ": 2.6985114210581203}
\ No newline at end of file
+{"Acute graft versus host disease": 83.38739046895434, "Acute graft versus host disease in intestine": 64.2556300606548, "Acute myeloid leukaemia": 9.619746996967937, "Adenovirus infection": 71.32142619791969, "Ascites": 3.146105082320292, "Bacteraemia": 11.243229974855714, "Blood lactate dehydrogenase increased": 4.079842593434381, "Cardiac failure": 2.68919127963062, "Cardiac failure congestive": 2.355415740033188, "Cardiomyopathy": 4.745125392259742, "Chronic graft versus host disease": 29.982214913207343, "Clostridium difficile colitis": 8.944070256971859, "Clostridium difficile infection": 7.037641393385618, "Colitis": 2.8259187327942668, "Congenital aplasia": 34.98050977499556, "Cystitis haemorrhagic": 19.226264651319976, "Cytomegalovirus infection": 11.41128180888587, "Cytomegalovirus infection reactivation": 47.8561605807521, "Cytomegalovirus viraemia": 34.398773285034835, "Drug ineffective for unapproved indication": 6.739094433697799, "Febrile neutropenia": 20.356831366201032, "Graft versus host disease in skin": 37.25819953393263, "Haemophagocytic lymphohistiocytosis": 22.19933142471585, "Hepatic cytolysis": 2.902636152879413, "Hepatitis B reactivation": 17.29619037851157, "Human herpesvirus 6 infection": 85.5061207606328, "Hypervolaemia": 12.324453460790409, "Hypoxia": 3.2047242109656606, "Incorrect product administration duration": 7.582793937870976, "Incorrect route of product administration": 7.8080470551423025, "Iris atrophy": 421.6769635803152, "Meningitis bacterial": 54.39845061524957, "Mucosal inflammation": 29.711473393345468, "Multiple organ dysfunction syndrome": 7.120862460936055, "Myelodysplastic syndrome": 18.383451752961964, "Neuropathy peripheral": 3.4996418070065687, "Neutropenia": 5.420484321934866, "Neutropenic colitis": 60.461402812124255, "Off label use": 5.628684557762224, "Pancytopenia": 7.517998685250997, "Plasma cell myeloma": 17.811635782609535, "Pleural effusion": 3.2633822434088904, "Pneumonia fungal": 27.487919385052948, "Product use in unapproved indication": 4.750272960421307, "Pulmonary hypertension": 6.042918517704777, "Respiratory failure": 3.8323219097854153, "Retinal degeneration": 124.06161256418096, "Sepsis": 3.486285435335649, "Septic shock": 7.366596790929221, "Staphylococcal infection": 4.4873874708435535, "Stomatitis": 5.63676359675866, "Thrombocytopenia": 4.619022684000691, "Thrombotic microangiopathy": 57.31363703392644, "Venoocclusive liver disease": 92.23983851412775, "Viraemia": 69.34003307326786}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/714.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/714.json
index f70f752aa83..1d185d37c47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/714.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/714.json
@@ -1 +1 @@
-{"Abscess ": 2.122205229408155, "Abscess limb ": 2.2822416028897563, "Action tremor ": 27.84286958552345, "Acute graft versus host disease ": 13.51308298186652, "Acute graft versus host disease in intestine ": 6.581540307748151, "Acute graft versus host disease in skin ": 10.958466725344543, "Acute lymphocytic leukaemia ": 4.344493844457715, "Acute myeloid leukaemia ": 4.306534482996878, "Acute respiratory distress syndrome ": 2.909579435012572, "Adenovirus infection ": 2.79352658759279, "Agranulocytosis ": 2.0361812506376182, "Airway remodelling ": 339.58378892615184, "Angiodysplasia ": 18.634936975850778, "Arthritis ": 3.6538095580888497, "Arthritis bacterial ": 11.7098688324948, "Arthritis infective ": 4.325801482980193, "Arthrodesis ": 14.677417560233964, "Aspergillus infection ": 3.070950899119901, "Atopy ": 153.53550276360943, "Atypical mycobacterial infection ": 5.047644442187632, "Autoinflammatory disease ": 29.169554532888203, "B-cell lymphoma ": 2.7643591427470477, "BK virus infection ": 4.770657727589728, "Bacteraemia ": 2.8035165209913875, "Bacterial infection ": 2.366458461609237, "Benign abdominal neoplasm ": 165.9414240888942, "Benign ovarian tumour ": 39.32899244457196, "Bicytopenia ": 2.3911908765952847, "Blood immunoglobulin E increased ": 12.2320088189661, "Blood iron decreased ": 4.2397270109538825, "Blood pressure diastolic abnormal ": 44.60910514567497, "Blood pressure diastolic decreased ": 9.399491748967844, "Blood pressure diastolic increased ": 12.986421946421276, "Blood pressure fluctuation ": 2.221300094559552, "Blood pressure systolic abnormal ": 39.57823648112768, "Blood pressure systolic increased ": 7.964291621386266, "Blood test abnormal ": 2.061911351679701, "Body temperature decreased ": 6.254419221704143, "Bone marrow failure ": 2.9496365084246565, "Bronchitis ": 3.2512474815829533, "Bronchopulmonary aspergillosis ": 2.549755574728489, "Bronchopulmonary dysplasia ": 11.590866869201236, "Bursa disorder ": 25.03159398630535, "C-reactive protein increased ": 2.931282845900943, "Cardiac septal defect ": 78.07940163432635, "Cardiotoxicity ": 2.213649456317265, "Catheter site pain ": 13.634770004585016, "Cell death ": 2.701128564906756, "Cellulitis ": 2.5520380525700643, "Central nervous system lymphoma ": 24.451601587179177, "Central nervous system mass ": 1229.3545372773394, "Cheilitis ": 5.041176657886832, "Cholelithiasis ": 2.0930801673690014, "Chondritis ": 79.55151568043685, "Chondrodermatitis nodularis chronica helicis ": 433.3969778062538, "Chronic graft versus host disease ": 5.662895687414068, "Chronic sinusitis ": 6.220702374888782, "Clinodactyly ": 16.890677860388443, "Cold urticaria ": 23.91936157796233, "Condition aggravated ": 2.670489593238829, "Congenital aplasia ": 3.298034464318245, "Congenital foot malformation ": 10.754129827194864, "Contusion ": 2.433857040288677, "Crohn's disease ": 2.009539107045673, "Cushingoid ": 6.302913247816661, "Cystitis ": 2.018333717302362, "Cystitis haemorrhagic ": 2.878927827237539, "Cytomegalovirus chorioretinitis ": 4.621902530687314, "Cytomegalovirus infection ": 2.704358660341864, "Cytomegalovirus infection reactivation ": 4.533693167267168, "Cytomegalovirus test positive ": 7.637652729705631, "Cytomegalovirus viraemia ": 4.04419748024166, "Dactylitis ": 15.335636897161702, "Dental restoration failure ": 39.22088388840281, "Dermatitis atopic ": 3.01407703555923, "Dermatitis exfoliative generalised ": 3.624599497675807, "Diaphragmatic disorder ": 11.402566925772032, "Diffuse alopecia ": 4.36622825250318, "Diffuse large B-cell lymphoma ": 4.2550864121936565, "Diffuse large B-cell lymphoma recurrent ": 8.067824499709847, "Disability assessment scale score increased ": 149.32577481034104, "Disease recurrence ": 2.145774538073849, "Disseminated intravascular coagulation ": 2.1577238682920936, "Disseminated tuberculosis ": 4.364934865312127, "Diverticulitis ": 4.263534888588175, "Drug clearance decreased ": 20.15825378359944, "Drug ineffective ": 2.608532987742045, "Drug ineffective for unapproved indication ": 2.650902310453519, "Drug resistance ": 2.2997523685923595, "Duodenitis ": 4.294912259135163, "Dyslipidaemia ": 2.4361771665827, "Ear infection ": 2.5140709592911725, "Encephalitis ": 3.267239466262561, "Endocarditis ": 2.2081796098312885, "Enthesopathy ": 3.1153764683877943, "Eosinophil count decreased ": 34.62703478432783, "Eosinophil count increased ": 6.440821610108237, "Eosinophilic granulomatosis with polyangiitis ": 8.405528270328112, "Eosinophilic myocarditis ": 77.54521044076739, "Eosinophilic pneumonia ": 11.611539858685896, "Epigastric discomfort ": 4.274281154185458, "Epstein-Barr virus associated lymphoproliferative disorder ": 9.562356267342984, "Epstein-Barr virus infection ": 2.349490599655975, "Epstein-Barr virus infection reactivation ": 6.482839888090762, "Erysipelas ": 2.936882119576772, "Escherichia urinary tract infection ": 4.667647904540283, "Eustachian tube dysfunction ": 19.56749366796689, "Febrile bone marrow aplasia ": 8.05808736448486, "Febrile neutropenia ": 5.939602253351101, "Fibromyalgia ": 5.409520646046038, "Fine motor skill dysfunction ": 2.601177752903931, "Finger deformity ": 2.205163117056464, "Follicular lymphoma ": 6.749275816961422, "Food allergy ": 3.545669948095321, "Foot deformity ": 3.603022210928081, "Fungal infection ": 4.672353284830303, "Gastroenteritis ": 2.212072920442408, "Graft versus host disease ": 4.565569365925122, "Graft versus host disease in gastrointestinal tract ": 4.449219040248449, "Graft versus host disease in skin ": 4.513754711445736, "Granulocytopenia ": 2.2536571219641703, "Grip strength decreased ": 29.255564376239136, "Growth retardation ": 6.372239753599802, "Haematotoxicity ": 2.695406933591852, "Haemoglobin increased ": 2.530238492929478, "Haemophagocytic lymphohistiocytosis ": 3.399820832663249, "Haemorrhagic disease of newborn ": 146.23141070904936, "Heart rate decreased ": 3.823242509053709, "Hepatic cirrhosis ": 2.402973221822516, "Hepatic cytolysis ": 3.384673012885153, "Hepatic enzyme abnormal ": 2.7086943387108438, "Hepatic enzyme increased ": 2.4627770087137715, "Hepatic fibrosis ": 3.11179458827036, "Hepatic steatosis ": 4.71717751563075, "Hepatitis ": 2.107396992549177, "Hepatitis B reactivation ": 7.572580587747764, "Hepatocellular injury ": 2.2773875282915883, "Hepatotoxicity ": 2.0846600525657006, "Hernia ": 2.0302163710272287, "Herpes simplex ": 3.795340454575125, "Herpes virus infection ": 2.6482337682729367, "Hiatus hernia ": 2.8967052859513065, "Hodgkin's disease ": 2.890843176311133, "Human papilloma virus test positive ": 5.461207995713782, "Hypersensitivity pneumonitis ": 5.647973478582461, "Hyperthermia malignant ": 4.156609620018274, "Hypertransaminasaemia ": 3.770724786589712, "Hypogammaglobulinaemia ": 5.217861004154536, "Hysterectomy ": 5.848384042759211, "Ichthyosis ": 37.07500869439725, "Illness ": 2.1048150467018893, "Immunosuppression ": 7.1884626568275305, "Infection ": 2.366666544110412, "Infusion related reaction ": 2.863534061549834, "Injection related reaction ": 2.80183805109018, "Interstitial lung disease ": 3.1066998989057337, "Intervertebral disc degeneration ": 2.230448978354386, "Joint destruction ": 7.382546500159423, "Joint effusion ": 5.324050424101543, "Joint stiffness ": 2.5267073441297434, "Joint swelling ": 4.705871396889209, "Kaposi's sarcoma ": 2.535430934241771, "Klebsiella infection ": 2.610137132189445, "Lacrimation increased ": 2.662963271355986, "Latent tuberculosis ": 8.986951198342148, "Leukaemia recurrent ": 9.15323382639019, "Leukoencephalopathy ": 17.08604728385845, "Leukopenia ": 3.176384803800352, "Ligament sprain ": 2.1705543009091555, "Limb mass ": 4.991275058257167, "Lip blister ": 5.037144722518463, "Lip injury ": 6.198313270573319, "Lip ulceration ": 6.239772171286459, "Localised infection ": 2.8038428788548546, "Loss of personal independence in daily activities ": 2.61209946774204, "Low density lipoprotein increased ": 2.966595679882067, "Lower respiratory tract congestion ": 18.264593881615117, "Lower respiratory tract infection ": 2.9778639035922114, "Lung adenocarcinoma ": 3.4577832475125985, "Lung consolidation ": 3.2079220134819004, "Lymphocyte count decreased ": 3.666409925860428, "Lymphoma ": 6.170391237017313, "Lymphopenia ": 5.689556556870365, "Lymphoproliferative disorder ": 37.01473173406536, "Magnetic resonance imaging abnormal ": 4.132993204264399, "Maternal exposure timing unspecified ": 5.702010758519705, "Microangiopathy ": 55.12684820623129, "Micrognathia ": 16.766266809103005, "Monocyte count increased ": 3.6640855520020255, "Morton's neuralgia ": 66.38308767528781, "Mouth ulceration ": 5.725417978367167, "Mucormycosis ": 4.1873357195622845, "Mucosal inflammation ": 6.074778511578046, "Muscle strain ": 3.617632397031544, "Musculoskeletal stiffness ": 2.890659585694976, "Myelodysplastic syndrome ": 2.3726271827000898, "Myelosuppression ": 5.883447214392253, "Nasal polyps ": 11.946702211061604, "Nasopharyngitis ": 3.237274759043305, "Necrotising fasciitis ": 2.4599786724159647, "Nephropathy toxic ": 2.1384798335530584, "Neurological decompensation ": 3.8714090403081256, "Neurotoxicity ": 2.313545862303196, "Neutropenia ": 2.657593509288287, "Neutropenic sepsis ": 7.470973468520317, "Neutrophil count decreased ": 2.716237198149511, "Nocardiosis ": 4.084859426525982, "Nodule ": 7.88998072764187, "Obesity ": 5.799859143616076, "Obstructive airways disorder ": 3.392206572951215, "Obstructive sleep apnoea syndrome ": 3.9948720926526544, "Oral herpes ": 2.1170145290911933, "Organising pneumonia ": 3.813203767555988, "Osteoarthritis ": 7.782439049524688, "Osteomyelitis ": 2.573782797896816, "Osteosarcoma ": 19.1398421968342, "Pancytopenia ": 7.106972193635807, "Pharyngitis ": 2.2388331904949275, "Pharyngitis streptococcal ": 3.105040603046501, "Photosensitivity reaction ": 2.380496607127948, "Pleurisy ": 3.2416719343756286, "Pneumatosis intestinalis ": 2.767444045561092, "Pneumocystis jirovecii pneumonia ": 13.386135596273306, "Pneumonia ": 2.1613951572911243, "Pneumonia bacterial ": 4.773284246319933, "Pneumonia cytomegaloviral ": 4.282878643601265, "Pneumonia fungal ": 4.121622652731253, "Pneumonia pneumococcal ": 4.958864340765277, "Pneumonitis ": 2.622805531827365, "Polyarthritis ": 3.1872655644592256, "Poor venous access ": 6.1303996282856295, "Post transplant lymphoproliferative disorder ": 4.8697238023389415, "Posterior reversible encephalopathy syndrome ": 6.247698308403684, "Postoperative wound infection ": 2.7115333809502022, "Product use in unapproved indication ": 2.394218057585121, "Productive cough ": 3.4274743557448204, "Progressive multifocal leukoencephalopathy ": 3.486667897006588, "Prostate cancer ": 2.986319699099029, "Pseudomonal bacteraemia ": 22.140759919258784, "Psoriasis ": 4.477999324788413, "Psoriatic arthropathy ": 6.121017501358987, "Pulmonary fibrosis ": 2.631852726935992, "Pulmonary toxicity ": 2.107913105681306, "Pulmonary tuberculosis ": 5.99254688417585, "Pulmonary vascular disorder ": 20.16678976526278, "Pyelonephritis ": 2.0914427937989326, "Rebound effect ": 6.54713590247154, "Red blood cell sedimentation rate increased ": 3.392075425820736, "Red cell distribution width increased ": 3.8916536283309098, "Renal disorder ": 2.22583144362492, "Respiratory symptom ": 17.53513735997219, "Respiratory tract congestion ": 2.605522694602895, "Respiratory tract infection ": 5.383637697661907, "Rhabdoid tumour ": 595.4633302978953, "Rheumatic disorder ": 2.565423139816607, "Rheumatoid arthritis ": 8.401388559503568, "Rheumatoid factor positive ": 2.507160281205742, "Rheumatoid nodule ": 17.952708853271382, "Rotator cuff repair ": 89.00792356516351, "Sarcoidosis ": 2.5206733875574825, "Scab ": 2.7699426964015026, "Second primary malignancy ": 2.266190270595195, "Sepsis ": 3.0208114548536757, "Septic shock ": 2.51473574896529, "Sinus congestion ": 2.541106465165386, "Sinusitis ": 2.014928352450434, "Skin abrasion ": 2.323556608149254, "Skin erosion ": 2.303265898630268, "Skin laceration ": 4.488539051743943, "Skin lesion ": 2.442156326896061, "Skin mass ": 2.0753808446780506, "Skin plaque ": 3.074013773105626, "Skin striae ": 4.224015695327822, "Sleep deficit ": 7.311567416306866, "Soft tissue swelling ": 12.658709017066622, "Spinal compression fracture ": 2.693235562519605, "Spinal stenosis ": 30.651788473055056, "Squamous cell carcinoma ": 3.1516098519335283, "Squamous cell carcinoma of the oral cavity ": 24.36838048705268, "Staphylococcal bacteraemia ": 3.0242383000642485, "Staphylococcal infection ": 2.679610827127905, "Staphylococcal sepsis ": 4.963234142527649, "Still's disease ": 11.21360636009102, "Stomatitis ": 2.782426752131696, "Streptococcal bacteraemia ": 11.687368563479223, "Stress ": 2.025588327997877, "Sweat gland tumour ": 58.27519382704307, "Syndactyly ": 6.558981165985358, "Synovitis ": 4.439000049782897, "Tenderness ": 11.126105987470062, "Therapeutic product effect incomplete ": 3.0071358602391656, "Therapeutic response decreased ": 3.5144034360343825, "Thrombotic microangiopathy ": 2.901458598411097, "Tooth abscess ": 8.726740897596994, "Transaminases increased ": 2.9807070703370773, "Treatment failure ": 6.266377635607415, "Tuberculosis ": 4.934652508115583, "Tumour lysis syndrome ": 2.831198008371969, "Umbilical hernia ": 3.0947730936955984, "Urinary tract infection bacterial ": 5.647778706045294, "Urinary tract infection pseudomonal ": 33.68296456542038, "Vaginal infection ": 4.382401532358941, "Vascular device infection ": 2.179155029112528, "Vasomotor rhinitis ": 78.17223334159516, "Venoocclusive disease ": 3.6738470418348266, "Venoocclusive liver disease ": 6.543758047401073, "Ventricular hypokinesia ": 2.60507311346161, "Viral haemorrhagic cystitis ": 8.128413012723303, "Viral infection ": 2.7474832173091137, "White blood cell count decreased ": 2.144316456136059}
\ No newline at end of file
+{"Abnormal behaviour": 7.068974726541299, "Aggression": 15.149752151390114, "Agitation": 9.545415854045324, "Altered state of consciousness": 2.7660166607834733, "Anal incontinence": 19.12740493642513, "Bradycardia": 3.785033148374866, "Cardiac failure congestive": 4.316551412735918, "Cerebrovascular accident": 2.2961916311975585, "Cognitive disorder": 3.068364178773824, "Confusional state": 4.257124430776476, "Death": 2.6635232559867386, "Dehydration": 6.913708609366456, "Delirium": 3.2981429538376545, "Dementia": 8.75329344637986, "Dementia Alzheimer's type": 18.50834631317517, "Dysphagia": 2.5070819687613435, "Electrocardiogram QT prolonged": 3.4258917463075487, "Fall": 5.643681997844154, "Gait disturbance": 3.2962038676691643, "Generalised tonic-clonic seizure": 3.6486530029508257, "Hallucination": 3.1470164016387168, "Hallucination, visual": 5.846093479961975, "Hyponatraemia": 2.622407360299305, "International normalised ratio increased": 2.9070948684615576, "Lethargy": 2.304281742699432, "Mental status changes": 7.662391456502933, "Myoclonus": 13.408167635860384, "Pneumonia aspiration": 7.397405507474271, "Psychomotor hyperactivity": 7.74236912757044, "Seizure": 3.826349337790607, "Somnolence": 2.3103710961321595, "Syncope": 2.2186167179552045, "Transient ischaemic attack": 4.296264435910807, "Treatment failure": 2.2051036223215963, "Urinary incontinence": 8.13235659100843, "Urinary tract infection": 6.981592341460958}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/715.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/715.json
index ff6b357d0da..a6cb1d4615e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/715.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/715.json
@@ -1 +1 @@
-{"Agitation ": 13.827537600908707, "Drug interaction ": 15.257888574229758, "Serotonin syndrome ": 224.85939299049392}
\ No newline at end of file
+{"Erythema": 3.4847251178668635, "Febrile convulsion": 44.177967816225895, "Injection site erythema": 9.239081312419753, "Injection site swelling": 6.5697580854623325, "Injection site warmth": 9.453555700609286, "Pyrexia": 4.403753940175887, "Rash": 2.622843291489126, "Urticaria": 3.650192534834957}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/716.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/716.json
index 4dfc496fe05..b8ee1a76e83 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/716.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/716.json
@@ -1 +1 @@
-{"Arrhythmia ": 7.923941572518663, "Arrhythmic storm ": 2550.613125453545, "Cardiac failure ": 11.69400575669215, "Drug ineffective ": 10.963606883826143, "Seizure ": 2.761654251671553, "Torsade de pointes ": 60.34591175080017, "Ventricular fibrillation ": 43.55973498245247, "Ventricular tachycardia ": 61.56323827028558}
\ No newline at end of file
+{"Blood pressure decreased": 2.27886739919685, "Bronchiolitis": 52.93327123661008, "Cellulitis": 14.478336598434163, "Cyanosis": 2.183137620277801, "Dyskinesia": 3.2774674902731102, "Eating disorder": 6.579215815227368, "Erythema": 5.466213026618282, "Extensive swelling of vaccinated limb": 15.1349492679496, "Eye movement disorder": 10.952024416446344, "Febrile convulsion": 4.88500163110623, "Flushing": 4.363958105086375, "Guillain-Barre syndrome": 5.002027772462974, "Head injury": 5.515812438376587, "Heart rate decreased": 3.1463137600313003, "Hyperpyrexia": 9.755469328811758, "Hypotonia": 4.5665996310314325, "Induration": 23.65567321618604, "Inflammation": 8.720738338297984, "Injected limb mobility decreased": 9.48919609341109, "Injection site erythema": 5.153677110621563, "Injection site induration": 7.687753755446627, "Injection site oedema": 17.44997447786477, "Injection site pruritus": 2.2141612325441598, "Injection site reaction": 2.547688211026684, "Irritability": 3.8496148963415657, "Local reaction": 25.032541326903686, "Localised oedema": 5.199834042457992, "Loss of consciousness": 3.845886275807599, "Lymphadenitis": 4.366706600740012, "Meningitis meningococcal": 135.67257430230964, "Meningococcal sepsis": 232.4328799216312, "Muscle rigidity": 7.146836995226273, "Neck pain": 2.168382562315345, "Oedema": 3.577665911248734, "Pallor": 10.72615151737391, "Peripheral swelling": 2.255393630937274, "Petechiae": 3.684071865941208, "Pharyngeal swelling": 2.147651021907916, "Pharyngitis": 4.873705111979427, "Photophobia": 5.292681490078892, "Presyncope": 5.491821028525964, "Product preparation issue": 8.599709621853313, "Seizure like phenomena": 37.53545852842799, "Skin warm": 12.859470211311724, "Swelling": 2.494978695153696, "Syncope": 7.617009509020827, "Syringe issue": 17.302810662372657, "Throat tightness": 2.4494990278266755, "Tonic clonic movements": 18.47153807110239, "Type III immune complex mediated reaction": 42.5449656612914, "Unresponsive to stimuli": 3.343976929613635, "Upper respiratory tract infection": 2.9832453852425265, "Urticaria": 2.1288943760301047, "Vaccination site cellulitis": 149.46037768367236, "Vaccination site erythema": 10.109563158396892, "Vaccination site induration": 38.6015465631628, "Vaccination site inflammation": 8.020744994118138, "Vaccination site joint swelling": 65.08829983941715, "Vaccination site oedema": 47.43242298537725, "Vaccination site pain": 2.1860909693921133, "Vaccination site pruritus": 2.9704376801071093, "Vaccination site reaction": 4.241724472995453, "Vaccination site swelling": 5.737976516164305, "Vaccination site warmth": 15.74673184308442, "Viral infection": 3.609901953220176}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/717.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/717.json
index ca466432047..4d104c9f421 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/717.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/717.json
@@ -1 +1 @@
-{"Aspergillus infection ": 77.7193910044586, "C-reactive protein increased ": 6.414061249752139, "Candida infection ": 32.02128236375394, "Drug ineffective ": 7.443433649457482, "Drug resistance ": 9.014122277824814, "Eosinophil count increased ": 26.70384928505748, "Hepatic failure ": 11.50809851459593, "Hepatic function abnormal ": 9.703154620030972, "Hypokalaemia ": 5.424385890857232, "Infection ": 2.8467628129589446, "Mucormycosis ": 130.36712523267298, "Multiple organ dysfunction syndrome ": 9.906876627679932, "Off label use ": 3.054272491049891, "Pathogen resistance ": 31.156905845030607, "Pneumonia ": 2.8753094547954787, "Product use in unapproved indication ": 2.081444949468219, "Respiratory failure ": 7.31632086666999, "Therapy non-responder ": 9.206278891030497}
\ No newline at end of file
+{"Abnormal sensation in eye": 11.501171529391137, "Accident": 3.2976782145321573, "Addison's disease": 44.98489942921089, "Adrenal insufficiency": 4.266572821861256, "Adverse drug reaction": 5.995506027628534, "Airway remodelling": 95.04338039409016, "Allergic sinusitis": 85.09985011209348, "Aortic stenosis": 6.970835242640028, "Aortic valve disease": 8.8594125817728, "Appetite disorder": 6.22232581972877, "Aspergillus infection": 5.674142225687422, "Asphyxia": 3.855459047678411, "Asplenia": 184.1422742360961, "Asthma": 32.7153463799968, "Asthmatic crisis": 25.5719103781166, "Atelectasis": 2.0424002982766574, "Atrial septal defect": 2.809111659497616, "Bacterial infection": 8.876262707418222, "Blood immunoglobulin E increased": 19.523328628624604, "Blood immunoglobulin M decreased": 66.55115972222717, "Blood pressure abnormal": 2.3207513570810647, "Blood pressure increased": 2.9974531997228624, "Blood pressure systolic decreased": 2.068092260798547, "Blood test abnormal": 5.697699662902504, "Breast disorder": 22.810568330639487, "Breast neoplasm": 13.881239992039015, "Breast operation": 24.30935649074644, "Breath sounds abnormal": 13.179252580808958, "Bronchial hyperreactivity": 6.571802273538505, "Bronchial obstruction": 97.31104283862877, "Bronchial secretion retention": 11.51529784322142, "Bronchial wall thickening": 7.435105788490433, "Bronchiectasis": 8.798508555583043, "Bronchiolitis": 2.048556564698317, "Bronchitis": 4.061483953309416, "Bronchitis chronic": 4.885305470744494, "Bronchopulmonary aspergillosis allergic": 15.109387759252774, "CFTR gene mutation": 2171.3791410812864, "Cardiac ablation": 14.54909453948945, "Cardiac murmur": 3.9400968666861353, "Cataract": 2.1421134509697866, "Cataract operation": 3.756138440232691, "Chemotherapy": 5.632198337381257, "Chest X-ray abnormal": 3.8667006130997432, "Chest discomfort": 3.286151644759156, "Choking": 5.190606981218683, "Chronic obstructive pulmonary disease": 5.356797525122354, "Coronavirus infection": 5.152137626814872, "Coronavirus test positive": 12.121675424153365, "Cough": 5.35294914101373, "Crepitations": 15.718223876537126, "Cushing's syndrome": 4.068204217798504, "Cushingoid": 13.052922153355247, "Cyst": 3.0815002917364214, "Decreased activity": 12.547635796866675, "Depressed mood": 2.1270667661309783, "Depressive symptom": 5.873194842758486, "Dermatitis allergic": 5.747382619444923, "Drug hypersensitivity": 2.3129977837530484, "Dysphonia": 2.2703431618936434, "Dyspnoea": 5.087648854660774, "Dyspnoea exertional": 12.649587302912025, "Ear disorder": 5.345516705539579, "Ear infection": 7.174479280279965, "Eczema": 6.198317509933217, "Emphysema": 6.736869588419506, "Eosinophil count abnormal": 237.13138448907017, "Eosinophil count decreased": 21.9199178890184, "Eosinophil count increased": 15.137365945883689, "Eosinophilia": 2.250464897874798, "Eosinophilic bronchitis": 57.956206649939226, "Eosinophilic granulomatosis with polyangiitis": 5.610060936559059, "Escherichia infection": 2.813342756027833, "Exposure to SARS-CoV-2": 45.95187635567599, "Extra dose administered": 2.607913807304313, "Eye irritation": 2.1513185143671967, "Eye pruritus": 8.665417544561432, "FEV1/FVC ratio decreased": 50.49218562455997, "Feeding disorder": 5.222092405354624, "Flank pain": 2.9213885661169456, "Forced expiratory volume abnormal": 53.08499381938294, "Forced expiratory volume decreased": 5.019148900134135, "Frustration tolerance decreased": 2.895621726559348, "Full blood count abnormal": 29.987776959368123, "Fungal infection": 5.479801799498355, "Gait inability": 2.3020708003487287, "Gastrointestinal obstruction": 15.228503661737228, "Gastrooesophageal reflux disease": 2.465345886843058, "General physical condition abnormal": 3.011572200364233, "Glaucoma": 8.802340678641276, "Granuloma": 10.249298806434682, "Haemoglobin abnormal": 4.497561333995736, "Head discomfort": 2.1443384261371845, "Heart sounds": 94.94397371702748, "Hepatic cyst": 7.419736213518512, "Hospitalisation": 4.218725899616056, "Hyperaemia": 8.995472859381866, "Ill-defined disorder": 2.538296634904736, "Immunoglobulins increased": 48.107009640165856, "Inappropriate schedule of product administration": 4.128400933964583, "Increased bronchial secretion": 21.00565974034652, "Infection": 3.685660416141848, "Influenza": 2.926509461097913, "Intentional dose omission": 7.068590195677527, "Intestinal haemorrhage": 5.832219902546267, "Intestinal stent insertion": 580.8220315751637, "Kyphosis": 11.499779349853936, "Laboratory test abnormal": 5.049106384806118, "Labyrinthitis": 9.8316859047665, "Lip pruritus": 18.57464567072249, "Lipohypertrophy": 10.575965746572052, "Loss of personal independence in daily activities": 25.21676261813224, "Lower respiratory tract congestion": 12.101453220457854, "Lower respiratory tract infection": 8.443928817877309, "Lumbar vertebral fracture": 3.091340074771621, "Lung diffusion disorder": 45.419413586157255, "Lung hyperinflation": 15.369183205740384, "Lung opacity": 3.5188333123903286, "Lymphadenopathy mediastinal": 9.317914272011151, "Macrocytosis": 10.828752650413414, "Magnetic resonance imaging heart": 108.32992707146788, "Middle insomnia": 12.030631464728597, "Mite allergy": 15.737469305911237, "Monocyte count increased": 3.756951696004841, "Mucosal disorder": 4.479125245023203, "Multiple allergies": 17.8668619402784, "Musculoskeletal chest pain": 8.122462130670872, "Mycobacterium avium complex infection": 17.892647380959893, "Nasal congestion": 7.567059375624751, "Nasal discharge discolouration": 148.72347303717603, "Nasal disorder": 5.78331089349596, "Nasal obstruction": 5.123196370833853, "Nasal polyps": 5.163375384250025, "Nasopharyngitis": 5.758684907586251, "Nerve compression": 4.544221162257472, "Neurosensory hypoacusis": 31.60168348045309, "Obstruction": 13.5181407418361, "Obstructive airways disorder": 33.666128061621805, "Ocular discomfort": 14.65765996492672, "Ocular hyperaemia": 6.110236397886297, "Oesophageal polyp": 131.54390962365645, "Oropharyngeal pain": 2.336461871642123, "Otitis media": 2.527674828621503, "Oxygen saturation abnormal": 4.298759269003549, "Oxygen saturation decreased": 3.164507946663062, "Pancreatitis relapsing": 25.91031256704573, "Perfume sensitivity": 40.96829894077768, "Pneumonia": 5.0654583782094, "Pneumonia respiratory syncytial viral": 30.197184288475004, "Polymyalgia rheumatica": 2.6449115508307184, "Polyp": 22.02660908161094, "Post-traumatic stress disorder": 6.664277284819295, "Presbyacusis": 26.90856146456372, "Product administration error": 2.251539315190804, "Product dose omission issue": 4.346561758753848, "Productive cough": 20.38724213177979, "Prolonged expiration": 64.67397885533937, "Prostatic disorder": 5.516557624495455, "Pulmonary congestion": 2.03500240364784, "Pulmonary eosinophilia": 19.22118185609669, "Pulmonary function test abnormal": 10.887217656256176, "Pulmonary mass": 9.732759694776211, "Rales": 21.555265529438767, "Rectal cancer": 8.68915438638606, "Red blood cell count increased": 9.140829037386766, "Reflux laryngitis": 56.08987901972864, "Respiration abnormal": 5.8901757780222646, "Respiratory disorder": 4.636085107492743, "Respiratory gas exchange disorder": 39.50302951491969, "Respiratory rate increased": 2.139448631381805, "Respiratory symptom": 10.724366934752467, "Respiratory tract congestion": 14.83630991418676, "Respiratory tract infection": 6.455759477256253, "Reversible airways obstruction": 165.7006865641942, "Rhinitis": 7.535323452131012, "Rhinorrhoea": 5.112885384448852, "Right ventricular dysfunction": 11.43245582346952, "Sarcoidosis": 3.1931654025227574, "Seasonal allergy": 24.72955207482545, "Secretion discharge": 6.83391463863827, "Sense of oppression": 3.972355871496021, "Sinus congestion": 16.455467576651376, "Sinus disorder": 5.42758990316825, "Sinusitis": 5.028846166511029, "Skin atrophy": 6.595300238857327, "Skin fragility": 52.95749480413028, "Skin laceration": 3.968381482933376, "Sleep apnoea syndrome": 3.718737958159209, "Sleep disorder due to a general medical condition": 93.38205534841774, "Sneezing": 2.7925246354354805, "Snoring": 8.734594978338489, "Social problem": 15.01936565344599, "Spirometry abnormal": 25.027962803260447, "Sputum abnormal": 33.354061536030514, "Sputum culture positive": 33.13517907411721, "Sputum discoloured": 73.46591168697522, "Sputum increased": 35.08631641109543, "Sputum purulent": 52.755494284713066, "Stent placement": 2.5496069484941244, "Stress": 4.566668863648776, "Symptom recurrence": 15.55784842889915, "Therapeutic product effect incomplete": 31.088087813891697, "Therapeutic response decreased": 2.1475883197035994, "Therapy cessation": 2.811456522562386, "Throat clearing": 4.854488317434065, "Tooth extraction": 2.3301321007260465, "Total lung capacity decreased": 27.430351528167726, "Transient ischaemic attack": 2.0425540552557746, "Unevaluable event": 2.0721294282260456, "Upper respiratory tract infection": 5.217154405834002, "Upper-airway cough syndrome": 21.699239513481643, "Urethritis": 13.146372379895867, "Urine abnormality": 3.9385853125583945, "Vaccination site haemorrhage": 18.39415335139857, "Viral infection": 7.503347980204133, "Vital capacity decreased": 33.78561988950926, "Wheelchair user": 16.193098744715243, "Wheezing": 42.6197133882217, "Wound infection": 6.120710053218754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/718.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/718.json
index 7a199997fe0..ff873645d24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/718.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/718.json
@@ -1 +1 @@
-{"Accident at work ": 53.41992311586037, "Acute kidney injury ": 3.9574255881122657, "Angina pectoris ": 2.0719069499589384, "Angina unstable ": 2.4281032381504866, "Angioedema ": 5.930562057395212, "Anuria ": 4.070834331402571, "Apraxia ": 16.189786321376353, "Atrial fibrillation ": 2.293629862795349, "Atrioventricular block complete ": 3.53843112563667, "Atrophic vulvovaginitis ": 55.166066792057, "Bite ": 36.44823989957512, "Blood alkaline phosphatase increased ": 3.519377595266276, "Blood chloride decreased ": 11.733266164072802, "Blood cholesterol abnormal ": 7.818801728442826, "Blood creatine phosphokinase increased ": 5.519030324085107, "Blood creatinine increased ": 4.062612593620676, "Blood iron decreased ": 5.281402190095919, "Blood parathyroid hormone increased ": 16.67973220125753, "Blood phosphorus increased ": 8.19004069031512, "Blood potassium increased ": 12.643692887980867, "Blood pressure abnormal ": 4.16251540948135, "Blood pressure decreased ": 4.842245579076026, "Blood pressure diastolic abnormal ": 10.497054259539944, "Blood pressure fluctuation ": 6.198692505277972, "Blood pressure inadequately controlled ": 14.111349640701574, "Blood pressure increased ": 6.917219605308899, "Blood pressure systolic abnormal ": 19.63180176255119, "Blood pressure systolic increased ": 4.52435770638701, "Blood sodium decreased ": 5.391005174904916, "Blood sodium increased ": 13.96356574100327, "Blood urea increased ": 7.788732948248307, "Blood uric acid increased ": 6.080403160675028, "Bradycardia ": 3.81211456152521, "Cardiogenic shock ": 3.3317117032888097, "Cerebral infarction ": 2.075308215495137, "Cholelithiasis ": 2.0002320010327863, "Chromaturia ": 2.080576936172821, "Colitis ischaemic ": 2.4768976150401465, "Colon cancer ": 4.389582527467555, "Cough ": 2.0027531417427524, "Cystitis ": 3.1682360593041827, "Dementia ": 2.3369754469001798, "Dermatitis exfoliative generalised ": 2.991691199469896, "Diabetic foot ": 7.003755022381172, "Diabetic nephropathy ": 9.56806342607366, "Drug eruption ": 4.733788404851223, "Drug-induced liver injury ": 3.139033172190663, "Emphysema ": 2.652561792605161, "Erythema multiforme ": 2.914292761250428, "Face oedema ": 2.666401938327362, "Faeces discoloured ": 2.0672971101502875, "Fall ": 2.056881009636048, "Gamma-glutamyltransferase increased ": 2.3476808176981048, "Generalised oedema ": 2.3712598512539462, "Gout ": 2.1256618449660927, "Growth hormone deficiency ": 141.43696076294944, "Gynaecomastia ": 2.5876431706376444, "Heart rate decreased ": 2.7864702642518, "Hepatic function abnormal ": 6.410125701386251, "Hepatitis acute ": 2.887657515316995, "Hepatitis fulminant ": 4.730475042130308, "Hepatocellular injury ": 3.5332855053765573, "Hyperkalaemia ": 14.4966059202757, "Hypertension ": 2.3738624981221395, "Hypertensive crisis ": 10.890207669079608, "Hypertonic bladder ": 12.76128493142163, "Hyperuricaemia ": 4.241342658728513, "Hypoglycaemia ": 2.0675464773376917, "Hyponatraemia ": 4.029462864451151, "Hypotension ": 4.558775653912811, "Hypovolaemia ": 3.90426144568914, "Infarction ": 5.090403872455663, "Interstitial lung disease ": 5.720546157244377, "Iron deficiency anaemia ": 2.774504229906312, "Jaundice ": 4.340460678317132, "Jaundice cholestatic ": 3.599795558981817, "Laryngeal oedema ": 2.215425717480759, "Left ventricular hypertrophy ": 5.381877839465967, "Liver disorder ": 6.399679187593398, "Loss of consciousness ": 2.2733326443293045, "Lung neoplasm malignant ": 2.2355367858452704, "Lymphocyte stimulation test positive ": 28.22185375056543, "Myocardial infarction ": 2.2968766678505657, "Nocturia ": 3.129573074762157, "Oedema peripheral ": 2.1783737509121246, "Orthostatic hypotension ": 7.423467141442469, "Pancreatic carcinoma stage III ": 212.43699148382075, "Pharyngeal oedema ": 5.952274516129602, "Pneumonia bacterial ": 4.173946467813583, "Product physical issue ": 2.749569767991811, "Product quality issue ": 2.769245848251092, "Pulmonary hypoplasia ": 33.60099092924455, "Rales ": 2.4997666088771604, "Renal artery stenosis ": 16.87920973434076, "Renal impairment ": 3.92047229222548, "Renal tubular necrosis ": 2.1123054684252303, "Rhabdomyolysis ": 5.05372756229684, "Road traffic accident ": 2.2818473215865467, "Shock ": 2.623139078968608, "Sinus node dysfunction ": 7.239345476126208, "Sjogren's syndrome ": 5.987998800269721, "Skin laceration ": 2.3016414544571653, "Stevens-Johnson syndrome ": 2.0262689667685527, "Syncope ": 2.355347912472822, "Tendonitis ": 2.7738688039730124, "Therapy non-responder ": 2.519897007988937, "Thrombocytopenic purpura ": 5.824137463988968, "Toxic skin eruption ": 3.1440399303818216}
\ No newline at end of file
+{"Acute hepatic failure": 7.286252685833618, "Acute lymphocytic leukaemia recurrent": 18.25062755230499, "Acute myeloid leukaemia": 13.278583353972556, "Agranulocytosis": 4.247945710048274, "Alanine aminotransferase increased": 3.265540397672038, "Amylase increased": 7.187581688332613, "Anaemia": 2.0649990733740107, "Bacteraemia": 10.442874608071186, "Blood bilirubin increased": 3.3106146820113995, "Bone marrow failure": 5.523346859949842, "Cholestasis": 2.5654483083139743, "Colitis ulcerative": 2.2620051157879253, "Crohn's disease": 6.482841448367913, "Cytomegalovirus chorioretinitis": 56.53385097496842, "Cytomegalovirus infection": 16.137830082619402, "Cytopenia": 7.541955418989596, "Diarrhoea haemorrhagic": 9.594908011361444, "Disease recurrence": 5.329007711682954, "Drug-induced liver injury": 4.525005879931241, "Exposure during pregnancy": 2.4990158991213347, "Febrile neutropenia": 48.12760360106366, "Haemoglobin decreased": 2.849995191699929, "Haemophagocytic lymphohistiocytosis": 15.902933191788792, "Hepatic function abnormal": 2.0733429737902336, "Hepatitis": 2.24263948258082, "Hepatosplenic T-cell lymphoma": 283.3076266174472, "Hepatotoxicity": 11.311071507863923, "Hyperbilirubinaemia": 5.757687995917776, "Jaundice": 4.156697746375263, "Langerhans' cell histiocytosis": 311.1436128783783, "Leukaemia recurrent": 32.24348423788619, "Leukopenia": 10.89165423313252, "Lipase increased": 7.887355123575658, "Liver function test abnormal": 4.5187029992341685, "Lymphopenia": 6.784266608939834, "Mental disorder": 3.3230953109504884, "Mouth ulceration": 3.622239048221112, "Mucosal inflammation": 5.426696409807521, "Myelodysplastic syndrome": 4.923730588694668, "Myelosuppression": 32.592704109853145, "Neutropenia": 6.15137480337798, "Neutrophil count decreased": 10.681341817571148, "Nodular regenerative hyperplasia": 137.04123107892494, "Off label use": 3.7853319238363263, "Pallor": 2.59762019533, "Pancreatitis": 6.472172500004766, "Pancreatitis acute": 6.945241939698022, "Pancreatitis necrotising": 25.46109767435728, "Pancytopenia": 15.90328864819556, "Platelet count decreased": 4.636155932454315, "Pneumocystis jirovecii pneumonia": 5.66493198243213, "Product use issue": 2.1887001071079064, "Sepsis": 2.986965082095666, "Splenomegaly": 4.7305053561537616, "Stomatitis": 2.3012551960688348, "Thrombocytopenia": 2.2820886874243795, "Upper respiratory tract infection": 3.036987620057717, "Viral infection": 4.008189660591511, "White blood cell count decreased": 8.44143221297215}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/719.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/719.json
index 96a02f35ee0..d6b7d86772b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/719.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/719.json
@@ -1 +1 @@
-{"Acute kidney injury ": 5.897491265979695, "Angioedema ": 2.5709492481470337, "Balance disorder ": 2.647555381000082, "Blood potassium decreased ": 8.607866497485936, "Blood pressure decreased ": 3.765903671417778, "Blood pressure increased ": 2.8455345326658343, "Cough ": 2.0341130240043888, "Dry mouth ": 4.474405118016654, "Electrolyte imbalance ": 16.370008908521847, "Erectile dysfunction ": 11.784280346717562, "Fall ": 2.9352075653624885, "Hyperkalaemia ": 8.32197494230159, "Hypertensive crisis ": 13.864332829667823, "Hyperuricaemia ": 56.98978011291496, "Hypokalaemia ": 6.3623501141381125, "Hyponatraemia ": 36.229688108395926, "Hypotension ": 9.432426115948225, "Inappropriate antidiuretic hormone secretion ": 15.451594909593137, "Lactic acidosis ": 7.595427151077852, "Orthostatic hypotension ": 14.462220024742669, "Pancreatitis ": 2.8276290756533724, "Photosensitivity reaction ": 10.022856636163448, "Presyncope ": 8.445860528172176, "Syncope ": 4.372505665074195, "Vertigo ": 3.2191524161022684}
\ No newline at end of file
+{"Herpes zoster": 17.952416527121674, "Vaccination failure": 3.301923646555068}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/72.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/72.json
index 6d71e05288b..258914e7504 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/72.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/72.json
@@ -1 +1 @@
-{"Anaemia ": 4.594814524997642, "Bradycardia ": 7.792302572196986, "Drug ineffective ": 2.3448740544693165, "Drug intolerance ": 9.591486456677035, "Dysaesthesia ": 73.24290938521547, "Haemoglobin decreased ": 11.317748609915052, "Myelofibrosis ": 245.4323693937629, "Paraesthesia ": 2.340609127628494, "Platelet count decreased ": 6.713019868553475, "Platelet count increased ": 70.73577353593751, "Sedation ": 29.8445940125878, "Somnolence ": 2.740874758088238, "Splenomegaly ": 66.15655087495634, "Vertigo ": 5.578272728764781}
\ No newline at end of file
+{"Depression": 5.2904288142913645, "Drug resistance": 27.7725328581426, "Hepatic enzyme increased": 8.899852357985706, "Lipodystrophy acquired": 147.90997635781167, "Non-alcoholic steatohepatitis": 683.7381828613328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/720.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/720.json
index ab3d0dce8ed..08183e96687 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/720.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/720.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 2.134830258057685, "Abortion induced ": 2.3308733405785, "Accidental overdose ": 3.2772688344760272, "Acidosis ": 3.491393240837627, "Acute generalised exanthematous pustulosis ": 4.007620142677752, "Acute pulmonary oedema ": 7.090307550211025, "Acute respiratory distress syndrome ": 4.233937740702786, "Acute respiratory failure ": 2.1240334981939646, "Aggression ": 2.5617096540558792, "Agitation ": 7.0282104316902245, "Airway complication of anaesthesia ": 85.7424050434213, "Altered state of consciousness ": 4.247545105585105, "Amino acid level increased ": 115.61316650366412, "Anaesthetic complication ": 17.363640920387503, "Anaesthetic complication neurological ": 638.7951811642432, "Anaphylactic reaction ": 10.714035223382403, "Anaphylactic shock ": 14.79348965057818, "Anaphylactoid reaction ": 8.223422863063975, "Anaphylactoid shock ": 26.216892794461685, "Anticholinergic syndrome ": 19.5927804513776, "Anuria ": 2.128129514204692, "Aortic valve incompetence ": 5.580864451503178, "Apgar score low ": 22.055562715950764, "Apnoea ": 16.42994024524625, "Apnoeic attack ": 29.364445466068627, "Areflexia ": 6.259808284129397, "Arteriospasm coronary ": 6.9711217604801305, "Aspiration ": 12.898824435837671, "Atelectasis ": 4.135318789284506, "Atrioventricular block ": 4.919717117374876, "Autonomic nervous system imbalance ": 8.422349659448837, "Blood bicarbonate decreased ": 11.685211860895532, "Blood calcium decreased ": 2.305060839480027, "Blood creatine phosphokinase increased ": 2.304687369559464, "Blood lactic acid increased ": 3.992186126185759, "Blood magnesium decreased ": 10.386767069033883, "Blood pH decreased ": 11.784678206314409, "Blood pressure decreased ": 3.6412948202447617, "Blood pressure immeasurable ": 23.64965313822041, "Blood pressure systolic decreased ": 9.454372172298322, "Blood sodium increased ": 12.322947252034432, "Bradycardia ": 6.083821605242825, "Bradycardia foetal ": 12.967504067582851, "Bradypnoea ": 13.7373675721881, "Brain death ": 13.21952862325068, "Brain injury ": 3.785393758160047, "Brain oedema ": 6.965477575144787, "Bronchoalveolar lavage abnormal ": 116.80149055447076, "Bronchospasm ": 10.829179709070996, "Caesarean section ": 4.137747097828348, "Cardiac arrest ": 8.956067360263303, "Cardio-respiratory arrest ": 5.166935993950047, "Cardiogenic shock ": 4.965314184854846, "Cardiomegaly ": 3.990734874356425, "Cardiopulmonary failure ": 4.795883744671636, "Cardiovascular insufficiency ": 7.11352083653256, "Cerebral atrophy ": 25.500959837984773, "Cerebral haemorrhage ": 2.120634154303149, "Cerebral haemorrhage foetal ": 226.19706200438043, "Cholestasis ": 4.444385194684785, "Circulatory collapse ": 4.2884347708225645, "Clonus ": 15.327477980575472, "Coma ": 6.380361981717264, "Coma scale abnormal ": 6.312785515866044, "Completed suicide ": 2.421722181057914, "Cyanosis ": 2.1236655575099395, "Deafness unilateral ": 3.3243087264971245, "Delayed recovery from anaesthesia ": 30.52847124930358, "Delirium ": 5.536483393001786, "Depressed level of consciousness ": 6.009667076279464, "Dermatitis allergic ": 3.1203076095173974, "Device related sepsis ": 18.09468777224527, "Diabetes insipidus ": 10.111722140553178, "Disseminated intravascular coagulation ": 3.650980435261428, "Drug abuse ": 3.74175798285502, "Drug diversion ": 7.726450048267389, "Drug ineffective for unapproved indication ": 2.849659646549826, "Drug interaction ": 3.5969596426390607, "Drug level increased ": 2.180560657222442, "Dyskinesia ": 3.587014186919083, "Dystonia ": 7.298356964346864, "Electrocardiogram QRS complex prolonged ": 7.360294660049282, "Electrocardiogram QT prolonged ": 2.3417716922055867, "Electrocardiogram ST segment elevation ": 11.507383922643507, "Electrocardiogram abnormal ": 3.972165131935523, "Electroencephalogram abnormal ": 16.373418698651413, "Encephalopathy ": 4.751640521574726, "Endotracheal intubation ": 5.455276681256489, "Exposure during pregnancy ": 2.360164679340845, "Exposure via breast milk ": 2.1679364316044296, "Extensor plantar response ": 28.5798163757589, "Extrasystoles ": 2.38297051537289, "Fibrinolysis ": 231.08493038647677, "Foetal death ": 7.863048526906474, "Foetal exposure during delivery ": 32.37946294066199, "Foetal exposure during pregnancy ": 4.222672279177228, "Foetal growth restriction ": 14.83003429392651, "Generalised tonic-clonic seizure ": 5.0388484692847335, "Grimacing ": 42.87806276964111, "Haemodynamic instability ": 18.69064788305545, "Hallucination ": 3.127397232006629, "Heart rate decreased ": 4.695325103821082, "Hepatic cytolysis ": 3.158776278356403, "Hiccups ": 2.8204241834172783, "Hydrothorax ": 21.10882132128616, "Hypercapnia ": 25.769717377265444, "Hyperreflexia ": 3.801511957690943, "Hyperthermia ": 6.094639495203747, "Hyperthermia malignant ": 47.17750809826777, "Hypertonia ": 8.426245774606347, "Hypopnoea ": 4.02092944542596, "Hypotension ": 6.600568184509002, "Hypothermia ": 3.0011687092186925, "Hypotonia ": 2.682739318414337, "Hypoventilation ": 31.46992846166537, "Hypovolaemic shock ": 5.578067120436186, "Hypoxia ": 7.946184836165208, "Hypoxic-ischaemic encephalopathy ": 13.915744659229526, "Ileus paralytic ": 7.676027778333676, "Incorrect drug administration rate ": 11.222394195799463, "Incorrect route of product administration ": 4.741102060308593, "Increased bronchial secretion ": 9.80254338599024, "Infantile apnoea ": 31.11785217764841, "Infusion site erythema ": 7.584866298569876, "Injection site urticaria ": 4.449521590604828, "Intentional overdose ": 2.247905576431754, "Intentional product misuse ": 4.460550945793516, "Intracranial pressure increased ": 4.731303430529409, "Kounis syndrome ": 16.56913123992617, "Laryngospasm ": 7.146323346559651, "Left ventricular dysfunction ": 8.197942745723498, "Left ventricular hypertrophy ": 4.096070028400209, "Leukocytosis ": 2.728538967873844, "Lip oedema ": 2.599667521392922, "Mechanical ventilation complication ": 78.83418505750022, "Medication error ": 2.2694086075189874, "Mental status changes ": 2.465309056845878, "Metabolic acidosis ": 6.131424777076011, "Miosis ": 5.535696703805512, "Mononucleosis syndrome ": 226.59276516001088, "Movement disorder ": 3.2797285819601587, "Multiple organ dysfunction syndrome ": 2.650422557865285, "Multiple-drug resistance ": 10.670049301128088, "Mumps ": 18.372625791282527, "Muscle rigidity ": 5.452083975718347, "Mydriasis ": 5.782620041476337, "Myoclonus ": 7.981299992959979, "Nephrogenic diabetes insipidus ": 7.828645544382011, "Nerve injury ": 2.6035976497468103, "Nervous system disorder ": 2.526842079333527, "Normal newborn ": 4.363273233136822, "Nystagmus ": 18.00325735264516, "Oliguria ": 3.1682871995420645, "Orthopnoea ": 5.3724385515650965, "Overdose ": 3.854359542732952, "Oxygen saturation abnormal ": 11.04670330123272, "Oxygen saturation decreased ": 10.08318538212028, "PCO2 increased ": 88.88622571793454, "PO2 increased ": 67.08828438022006, "Paradoxical drug reaction ": 32.84851213305368, "Partial seizures ": 9.50264505072604, "Pneumothorax ": 2.8169399658541883, "Poisoning ": 6.547846293031295, "Poisoning deliberate ": 8.142820011314287, "Poor feeding infant ": 17.71409520889765, "Post procedural haemorrhage ": 2.40358989308267, "Postoperative delirium ": 40.88554487595712, "Potentiating drug interaction ": 4.55981190567656, "Premature baby ": 2.1105320507358947, "Premature delivery ": 2.2668278066916305, "Product administered to patient of inappropriate age ": 4.788238682462222, "Product contamination physical ": 44.27052488058702, "Propofol infusion syndrome ": 15.999732858016284, "Psychomotor hyperactivity ": 5.474875171976252, "Pulmonary hypertensive crisis ": 82.23507540598621, "Pulmonary oedema ": 2.899821349568149, "Pulmonary toxicity ": 2.8981808990452955, "Pulmonary vascular disorder ": 73.89671725978071, "Pulse absent ": 11.9988486016156, "Pulseless electrical activity ": 15.491618592603688, "Pupillary reflex impaired ": 17.40373183429188, "Quadriplegia ": 12.419381586591715, "Rash maculo-papular ": 2.5828295005712776, "Renal ischaemia ": 56.07505156395093, "Respiration abnormal ": 4.333224447277258, "Respiratory acidosis ": 12.832259779831972, "Respiratory arrest ": 12.274701265957283, "Respiratory depression ": 30.651226131331384, "Respiratory disorder ": 2.538912377895171, "Respiratory distress ": 4.208192137088547, "Respiratory failure ": 5.499267495460927, "Respiratory rate decreased ": 6.054903238358053, "Respiratory rate increased ": 6.413143645879517, "Respiratory symptom ": 6.9683458417701365, "Restlessness ": 2.086160344776439, "Resuscitation ": 10.407503097962907, "Rhabdomyolysis ": 3.750315903647772, "Salivary hypersecretion ": 2.9668558410389174, "Schizencephaly ": 345.17629877803074, "Sedation ": 7.712113909653155, "Sedation complication ": 31.106211474758755, "Seizure ": 2.646600842335089, "Seizure like phenomena ": 24.69596755079265, "Serotonin syndrome ": 2.819100199761688, "Sinus tachycardia ": 6.824046963811249, "Somnolence ": 2.119742858544856, "Status epilepticus ": 15.10022263587256, "Stillbirth ": 8.019766682692266, "Stress cardiomyopathy ": 11.479068475452708, "Stupor ": 3.630988388418596, "Substance abuse ": 2.8201015187194085, "Sudden death ": 2.672468995177815, "Tachycardia ": 3.3846395221081487, "Tachyphylaxis ": 62.39276566404961, "Tachypnoea ": 2.6249652405781188, "Therapeutic response decreased ": 2.3633189408760296, "Therapy change ": 11.153434315403125, "Tonic convulsion ": 6.42482942222802, "Torsade de pointes ": 6.301394946101258, "Toxicity to various agents ": 4.682827189843585, "Tricuspid valve disease ": 56.46123559393571, "Type I hypersensitivity ": 7.4184987359905294, "Unresponsive to stimuli ": 9.047745310812244, "Unwanted awareness during anaesthesia ": 112.9254495135968, "Urinary tract candidiasis ": 108.9697483895517, "Ventricular extrasystoles ": 4.772773538230685, "Ventricular fibrillation ": 5.5421267164729375, "Ventricular tachycardia ": 3.272706574472644, "Withdrawal syndrome ": 4.036457781618344, "Wrong patient received product ": 7.322811070309023}
\ No newline at end of file
+{"Cerebral haematoma": 393.1247726909989, "Cerebral haemorrhage": 179.7815841222343}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/721.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/721.json
index 8da6b6b87eb..b7a9647f061 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/721.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/721.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 31.715570770834983, "Acute myeloid leukaemia recurrent ": 193.72812723359, "Ascites ": 12.16445840759628, "Drug interaction ": 2.5009466553780597, "Electrocardiogram QT prolonged ": 12.564313883995508, "Febrile neutropenia ": 16.53198203611618, "Malignant neoplasm progression ": 6.537038938722183, "Neutropenia ": 2.795933988644413, "Sepsis ": 6.140103921427586, "Septic shock ": 10.536515340003334, "Thrombocytopenia ": 4.082471137701314}
\ No newline at end of file
+{"Abdominal distension": 2.2104922963478755, "Acute kidney injury": 2.232717283082681, "Altered state of consciousness": 6.941119395343088, "Anuria": 10.079941522585113, "Appetite disorder": 12.024749024022574, "Blister": 18.133870710081453, "Blister rupture": 449.7576783969333, "Blood creatine phosphokinase increased": 2.1680684738045417, "Blood glucose increased": 4.824011318469732, "Blood ketone body increased": 45.93996937265378, "Blood lactic acid increased": 12.380623713043832, "Blood pressure systolic increased": 12.905443169736596, "Blood thyroid stimulating hormone increased": 22.850829720844008, "Cardiac failure": 2.636524551751227, "Cerebral infarction": 3.3476222809366543, "Cognitive disorder": 4.855232540577087, "Concomitant disease aggravated": 26.42028381085322, "Concomitant disease progression": 22.234402459292085, "Constipation": 2.742269283501876, "Decreased appetite": 3.022241609908603, "Dehydration": 5.848242093057954, "Dementia": 5.124658783209105, "Dermatitis": 6.073827379398334, "Dermatitis bullous": 9.986265913816217, "Diabetes mellitus inadequate control": 46.19856862577995, "Diabetic nephropathy": 28.19550425164873, "Dyslipidaemia": 36.77333980987071, "Eczema": 4.663305494999279, "Eosinophilia": 3.779736757670315, "Erythema": 2.946022757553235, "Food allergy": 21.643411920315177, "Gastrooesophageal reflux disease": 3.853063278370715, "Glomerular filtration rate decreased": 3.82382876781628, "Glycosylated haemoglobin increased": 29.01814730792279, "Haematocrit decreased": 10.207662634458815, "Haemoglobin decreased": 2.2575391355425576, "Hepatic function abnormal": 2.63039415612761, "Hepatic steatosis": 16.351750291338135, "Hyperglycaemia": 5.702916967877856, "Hyperkalaemia": 3.8374607130998695, "Hypoglycaemia": 5.966119298595938, "Hypophagia": 5.958762500351369, "Hypothyroidism": 3.5956081282438097, "Inflammation": 3.748159034537753, "Intercepted product prescribing error": 103.4576834254992, "Lactic acidosis": 37.51443785708738, "Lymphocyte count decreased": 19.43411798016228, "Metabolic acidosis": 4.27529891119734, "Metastases to liver": 3.755512816027257, "Mucosal disorder": 28.135875336172823, "Neutrophil count decreased": 3.0516477482557485, "Pancreatic carcinoma": 4.979488155907248, "Pancreatitis acute": 4.618796183190683, "Papule": 4.364007459109607, "Pemphigoid": 186.7322681135001, "Physical deconditioning": 29.53439335498188, "Prostate cancer": 10.83510027665936, "Proteinuria": 7.345176640142861, "Red blood cell count decreased": 7.5991257544354385, "Renal impairment": 6.583843222247448, "Respiratory syncytial virus infection": 11.58714688475367, "Rhabdomyolysis": 2.844466851094132, "SARS-CoV-2 test positive": 3.699339718112823, "Shock": 3.327023834886204, "Skin erosion": 57.99069923596083, "Skin exfoliation": 9.748322001508733, "Splenomegaly": 15.579364799229324, "Tachypnoea": 2.927355990323285, "Tonsil cancer": 142.19237395618146, "Treatment noncompliance": 3.459413085796258, "Tuberculosis": 20.661724594586023, "Type 2 diabetes mellitus": 13.024930574956072, "Vitamin D deficiency": 12.499801468984623, "Weight decreased": 2.6985114210581203}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/722.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/722.json
index 05bd6d913c0..1dc08151c20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/722.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/722.json
@@ -1 +1 @@
-{"Hypersensitivity myocarditis ": 56617.2757639899}
\ No newline at end of file
+{"Abscess": 2.121080735885112, "Abscess limb": 2.2810323471018603, "Action tremor": 27.828116999397658, "Acute graft versus host disease": 13.505922343214696, "Acute graft versus host disease in intestine": 6.578053024986727, "Acute graft versus host disease in skin": 10.952660047140624, "Acute lymphocytic leukaemia": 4.342191857889745, "Acute myeloid leukaemia": 4.304252452313631, "Acute respiratory distress syndrome": 2.908037680598957, "Adenovirus infection": 2.792046421402069, "Agranulocytosis": 2.035102244476457, "Airway remodelling": 339.4038530446654, "Angiodysplasia": 18.62506321705894, "Arthritis": 3.651873205586637, "Arthritis bacterial": 11.703663942173794, "Arthritis infective": 4.323509405664458, "Arthrodesis": 14.669640549769095, "Aspergillus infection": 3.069323690797092, "Atopy": 153.45414717964348, "Atypical mycobacterial infection": 5.044969926343649, "Autoinflammatory disease": 29.15409874430446, "B-cell lymphoma": 2.762894438955893, "BK virus infection": 4.768129938048894, "Bacteraemia": 2.802031010814693, "Bacterial infection": 2.365204523278816, "Benign abdominal neoplasm": 165.8535008077542, "Benign ovarian tumour": 39.30815394333663, "Bicytopenia": 2.3899238970500445, "Blood immunoglobulin E increased": 12.225527173885816, "Blood iron decreased": 4.237480487156184, "Blood pressure diastolic abnormal": 44.58546697680469, "Blood pressure diastolic decreased": 9.394511085629638, "Blood pressure diastolic increased": 12.979540630511588, "Blood pressure fluctuation": 2.2201230547442217, "Blood pressure systolic abnormal": 39.55726428846146, "Blood pressure systolic increased": 7.960071148518089, "Blood test abnormal": 2.060818802267369, "Body temperature decreased": 6.251105016337291, "Bone marrow failure": 2.948073556023548, "Bronchitis": 3.249328313905355, "Bronchopulmonary aspergillosis": 2.548404542499461, "Bronchopulmonary dysplasia": 11.584725403687584, "Bursa disorder": 25.01833095489216, "C-reactive protein increased": 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chorioretinitis": 4.619453571683094, "Cytomegalovirus infection": 2.7029256614136465, "Cytomegalovirus infection reactivation": 4.531290874502692, "Cytomegalovirus test positive": 7.633605774737127, "Cytomegalovirus viraemia": 4.042054596582786, "Dactylitis": 15.32751110512211, "Dental restoration failure": 39.20010208268797, "Dermatitis atopic": 3.0124799840655734, "Dermatitis exfoliative generalised": 3.622678885237523, "Diaphragmatic disorder": 11.396525231583048, "Diffuse alopecia": 4.363914781679276, "Diffuse large B-cell lymphoma": 4.252831757282672, "Diffuse large B-cell lymphoma recurrent": 8.063549626114202, "Disability assessment scale score increased": 149.24665081034198, "Disease recurrence": 2.1446375083347866, "Disseminated intravascular coagulation": 2.1565805228021486, "Disseminated tuberculosis": 4.362622085856881, "Diverticulitis": 4.261275584389175, "Drug clearance decreased": 20.14757276089974, "Drug ineffective": 2.608812217582236, "Drug ineffective for unapproved 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2.707259107679366, "Hepatic enzyme increased": 2.4614718445287496, "Hepatic fibrosis": 3.1101457860032475, "Hepatic steatosis": 4.714677839340835, "Hepatitis": 2.1062802593966663, "Hepatitis B reactivation": 7.568568022542653, "Hepatocellular injury": 2.275515237003312, "Hepatotoxicity": 2.083555401659189, "Hernia": 2.0291406276478794, "Herpes simplex": 3.793329399807715, "Herpes virus infection": 2.646830550476622, "Hiatus hernia": 2.895170374025387, "Hodgkin's disease": 2.8893114503999877, "Human papilloma virus test positive": 5.458314359530697, "Hypersensitivity pneumonitis": 5.644980839759978, "Hyperthermia malignant": 4.154407195791473, "Hypertransaminasaemia": 3.768726715925843, "Hypogammaglobulinaemia": 5.215096236266903, "Hysterectomy": 5.84528516493047, "Ichthyosis": 37.05536417913332, "Illness": 2.103699595201077, "Immunosuppression": 7.184653633621811, "Infection": 2.365412300999348, "Infusion related reaction": 2.8620165609026653, "Injection related reaction": 2.800353488995893, "Interstitial lung disease": 3.1050534192314587, "Intervertebral disc degeneration": 2.22926714080512, "Joint destruction": 7.3786347981135645, "Joint effusion": 5.321229302866509, "Joint stiffness": 2.5253684594501427, "Joint swelling": 4.703377187138256, "Kaposi's sarcoma": 2.534087528698, "Klebsiella infection": 2.608754135930819, "Lacrimation increased": 2.6615521789863257, "Latent tuberculosis": 8.982189379317047, "Leukaemia recurrent": 9.148383840212336, "Leukoencephalopathy": 17.076993447106204, "Leukopenia": 3.174298445717016, "Ligament sprain": 2.169404214415728, "Limb mass": 4.988630389992835, "Lip blister": 5.034475737607427, "Lip injury": 6.195029077388318, "Lip ulceration": 6.236465993299544, "Localised infection": 2.8023571794986317, "Loss of personal independence in daily activities": 2.6107151994741296, "Low density lipoprotein increased": 2.965023797082499, "Lower respiratory tract congestion": 18.25491608987079, "Lower respiratory tract infection": 2.9762858626803506, "Lung adenocarcinoma": 3.4559511212375784, "Lung consolidation": 3.2062222820226856, "Lymphocyte count decreased": 3.6644671561008, "Lymphoma": 6.167121540085994, "Lymphopenia": 5.686541626353795, "Lymphoproliferative disorder": 36.9951177851043, "Magnetic resonance imaging abnormal": 4.13080330349465, "Maternal exposure timing unspecified": 5.698989428584896, "Microangiopathy": 55.09763713330798, "Micrognathia": 16.757383097886745, "Monocyte count increased": 3.662144110433146, "Morton's neuralgia": 66.34791428288914, "Mouth ulceration": 5.722383940215079, "Mucormycosis": 4.185117024974062, "Mucosal inflammation": 6.071559249894912, "Muscle strain": 3.615715535694063, "Musculoskeletal stiffness": 2.8891276203212093, "Myelodysplastic syndrome": 2.371369981406714, "Myelosuppression": 5.8803287338715, "Nasal polyps": 11.940371747380482, "Nasopharyngitis": 3.246521577487384, "Necrotising fasciitis": 2.45867524546414, "Nephropathy toxic": 2.1373467033537845, "Neurological decompensation": 3.869357757511919, "Neurotoxicity": 2.3123199594692885, "Neutropenia": 2.656070043839061, "Neutropenic sepsis": 7.467014748638735, "Neutrophil count decreased": 2.7147977367558638, "Nocardiosis": 4.082695052111509, "Nodule": 7.885799736326497, "Obesity": 5.796785753980992, "Obstructive airways disorder": 3.390409058055038, "Obstructive sleep apnoea syndrome": 3.9927553532494464, "Oral herpes": 2.115892754861277, "Organising pneumonia": 3.811183264613148, "Osteoarthritis": 7.778314653009637, "Osteomyelitis": 2.572419019845675, "Osteosarcoma": 19.12970078700149, "Pancytopenia": 7.103205367423149, "Pharyngitis": 2.237128838322657, "Pharyngitis streptococcal": 3.10339538373158, "Photosensitivity reaction": 2.379235199989916, "Pleurisy": 3.2399542689657204, "Pneumatosis intestinalis": 2.765977707225652, "Pneumocystis jirovecii pneumonia": 13.379041875491554, "Pneumonia": 2.1602495411528664, "Pneumonia bacterial": 4.770754973417148, "Pneumonia cytomegaloviral": 4.280609336018784, "Pneumonia fungal": 4.119438752789595, "Pneumonia pneumococcal": 4.956236872611846, "Pneumonitis": 2.62141569605558, "Polyarthritis": 3.1855767273513207, "Poor venous access": 6.127151393756671, "Post transplant lymphoproliferative disorder": 4.8671434813260905, "Posterior reversible encephalopathy syndrome": 6.24438767557578, "Postoperative wound infection": 2.71009665931964, "Product use in unapproved indication": 2.3928740975055813, "Productive cough": 3.425658042381957, "Progressive multifocal leukoencephalopathy": 3.484820444395952, "Prostate cancer": 2.984737242389063, "Pseudomonal bacteraemia": 22.12902840013795, "Psoriasis": 4.475626192928546, "Psoriatic arthropathy": 6.117773733540618, "Pulmonary fibrosis": 2.6304581231572906, "Pulmonary toxicity": 2.1067961956225303, "Pulmonary tuberculosis": 5.989371586418247, "Pulmonary vascular disorder": 20.1561043239718, "Pyelonephritis": 2.090334608606345, "Rebound effect": 6.5436668042252055, "Red blood cell sedimentation rate increased": 3.390278011525089, "Red cell distribution width increased": 3.889591593812476, "Renal disorder": 2.224322228293761, "Respiratory symptom": 17.52584556303686, "Respiratory tract congestion": 2.6041421242068084, "Respiratory tract infection": 5.380784836710125, "Rhabdoid tumour": 595.147822894265, "Rheumatic disorder": 2.5640638288053124, "Rheumatoid arthritis": 8.408070142072477, "Rheumatoid factor positive": 2.505831804615381, "Rheumatoid nodule": 17.943195945349952, "Rotator cuff repair": 88.96075871633568, "Sarcoidosis": 2.519337770211924, "Scab": 2.767576732037868, "Second primary malignancy": 2.2649894858586084, "Sepsis": 3.019210522091471, "Septic shock": 2.513403170359279, "Sinus congestion": 2.539760032355505, "Sinusitis": 2.013860612433495, "Skin abrasion": 2.3223254492390524, "Skin erosion": 2.302045496753855, "Skin laceration": 4.486160640009123, "Skin lesion": 2.440862231739434, "Skin mass": 2.0742811791635, "Skin plaque": 3.0723849447232734, "Skin striae": 4.221777588602435, "Sleep deficit": 7.307693305337182, "Soft tissue swelling": 12.652001671199791, "Spinal compression fracture": 2.6918085022813925, "Spinal stenosis": 30.635544934289346, "Squamous cell carcinoma": 3.1499399047769336, "Squamous cell carcinoma of the oral cavity": 24.355468824624463, "Staphylococcal bacteraemia": 3.0226358820732258, "Staphylococcal infection": 2.678190918297961, "Staphylococcal sepsis": 4.96060426859391, "Still's disease": 11.207664690089864, "Stomatitis": 2.780952231321607, "Streptococcal bacteraemia": 11.68117596623713, "Stress": 2.024514967997303, "Sweat gland tumour": 58.24431663935158, "Syndactyly": 6.55550587207201, "Synovitis": 4.436647745167683, "Tenderness": 11.120209532348198, "Therapeutic product effect incomplete": 3.005542210933668, "Therapeutic response decreased": 3.512541059595089, "Thrombotic microangiopathy": 2.899921193869577, "Tooth abscess": 8.722116733686994, "Transaminases increased": 2.978943883130511, "Treatment failure": 6.263056471873528, "Tuberculosis": 4.932037674318972, "Tumour lysis syndrome": 2.829697838140508, "Umbilical hernia": 3.093133314663388, "Urinary tract infection bacterial": 5.64478618414307, "Urinary tract infection pseudomonal": 33.66511738669085, "Vaginal infection": 4.380079469928822, "Vascular device infection": 2.1780003911561456, "Vasomotor rhinitis": 78.13081328255721, "Venoocclusive disease": 3.671900438072597, "Venoocclusive liver disease": 6.540290630002817, "Ventricular hypokinesia": 2.6036927969278136, "Viral haemorrhagic cystitis": 8.12410615184938, "Viral infection": 2.746027345086657, "White blood cell count decreased": 2.1431800331990267}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/723.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/723.json
index ecfe2f350e2..ff454934e3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/723.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/723.json
@@ -1 +1 @@
-{"Abdominal pain upper ": 2.0797347128692896, "Adenoma benign ": 142.36102134351103, "Angiopathy ": 10.238481164956204, "Blood calcium abnormal ": 155.49474724300757, "Blood calcium decreased ": 39.458404272688206, "Blood calcium increased ": 74.11910324376421, "Blood parathyroid hormone abnormal ": 853.2897477860769, "Blood parathyroid hormone decreased ": 68.61286924326238, "Blood parathyroid hormone increased ": 881.6131772894765, "Blood phosphorus decreased ": 22.28517840000421, "Blood phosphorus increased ": 26.900931614474924, "Bone pain ": 3.456732685835604, "Brown tumour ": 2998.3560143191157, "Calciphylaxis ": 153.1362978240474, "Cardiac failure ": 4.138387041176018, "Dementia ": 3.6802490962045935, "Dialysis ": 8.007333561418653, "Drug intolerance ": 13.614901194244338, "Dysphagia ": 10.24079618002619, "Electrocardiogram QT prolonged ": 2.017175315794044, "Eosinophilia ": 2.0786496488732835, "Epilepsy ": 2.533047565713162, "Erectile dysfunction ": 3.4881885459392232, "Gait inability ": 3.216013705819196, "Gastric haemorrhage ": 5.117987947110145, "Gastrointestinal disorder ": 9.903060537196342, "Gastrointestinal tube insertion ": 167.58058502170368, "Gastrostomy ": 155.17940999063666, "General physical health deterioration ": 2.3062790571342644, "Hospitalisation ": 3.356559704483112, "Hungry bone syndrome ": 1741.8962004735863, "Hypercalcaemia ": 58.74948521661065, "Hyperkalaemia ": 2.333956010667844, "Hyperparathyroidism ": 27.879968664447784, "Hyperphosphataemia ": 21.13003939953836, "Hypertensive crisis ": 4.509104610279337, "Hypocalcaemia ": 164.03636205488937, "Hypophosphataemia ": 11.28326852222456, "Malnutrition ": 6.854318975706754, "Muscle spasms ": 2.4120189069019107, "Nausea ": 2.131888829471804, "Nephrocalcinosis ": 80.32732908656111, "Nephrolithiasis ": 2.402138534431345, "Off label use ": 2.488066485273714, "Parathyroid disorder ": 147.73537481203763, "Parathyroid tumour benign ": 487.32319843541393, "Parathyroid tumour malignant ": 819.8834597316322, "Parathyroidectomy ": 988.230776727609, "Premature delivery ": 5.409134156361651, "Purpura ": 3.4626281311087963, "Rash pruritic ": 3.789961535698939, "Renal transplant ": 47.82512990416674, "Skin ulcer ": 4.911313439209337, "Surgery ": 2.374930569350868, "Tetany ": 45.6760341801204, "Therapeutic product effect incomplete ": 2.550045975516255, "Therapy non-responder ": 5.927293972471666, "Transaminases increased ": 3.1103871488772743, "Transplant ": 44.51280032992484, "Treatment noncompliance ": 5.726543965145249, "Underdose ": 11.165910865547437, "Unevaluable event ": 4.113144049503172, "Vomiting ": 2.29419501350584, "Wrong technique in product usage process ": 6.851611353012378}
\ No newline at end of file
+{"Agitation": 13.827537600908707, "Drug interaction": 15.257888574229758, "Serotonin syndrome": 224.85939299049392}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/724.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/724.json
index 3845ca6dc5b..a93eba155e8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/724.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/724.json
@@ -1 +1 @@
-{"Altered state of consciousness ": 5.39633365741133, "Atrial fibrillation ": 2.1080446807391726, "Blood pressure increased ": 6.980449298273246, "Constipation ": 3.633571707781436, "Drug interaction ": 2.963879047645045, "Dry mouth ": 4.327617987246495, "Dysuria ": 12.844730137379438, "Hyperammonaemia ": 30.185213718404963, "Hypercholesterolaemia ": 17.775597585053816, "Hypertension ": 7.971688112915015, "Implant site extravasation ": 367.6303099999968, "Incorrect route of product administration ": 8.5014818066818, "Intentional product misuse ": 3.649053886918591, "Lumbar vertebral fracture ": 66.75008605453684, "Muscle spasms ": 2.885954298210821, "Muscle spasticity ": 25.37170189770751, "Narcolepsy ": 112.2460116099052, "Neuropathy peripheral ": 2.9702303373441934, "Osteoporosis ": 2.106147722018445, "Palpitations ": 4.400537275479096, "Plicated tongue ": 426.50703372673775, "Pollakiuria ": 8.62787136213413, "Radial nerve injury ": 1483.774764809838, "Rectal prolapse ": 320.3578260631208, "Restless legs syndrome ": 13.378735557660166, "Rosacea ": 69.51356078794029, "Rotator cuff syndrome ": 25.548840965612587, "Spinal compression fracture ": 29.39997681632112, "Tachycardia ": 4.262459170990752, "Ulnar nerve injury ": 918.679257440768, "Urinary retention ": 24.650958829031502, "Urinary tract infection ": 7.128593923958391, "Urinary tract infection bacterial ": 113.56636034178511, "Vitamin B6 deficiency ": 1151.6607132013544}
\ No newline at end of file
+{"Arrhythmia": 7.923941572518663, "Arrhythmic storm": 2550.613125453545, "Cardiac failure": 11.692938354053208, "Drug ineffective": 10.963525825756916, "Seizure": 2.7613481430958875, "Torsade de pointes": 60.34591175080017, "Ventricular fibrillation": 43.55973498245247, "Ventricular tachycardia": 61.56323827028558}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/725.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/725.json
index 717bdc07737..92130f81477 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/725.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/725.json
@@ -1 +1 @@
-{"Somnolence ": 6.10735563055617}
\ No newline at end of file
+{"Aspergillus infection": 77.7193910044586, "C-reactive protein increased": 6.414061249752139, "Candida infection": 32.02128236375394, "Drug ineffective": 7.443378609002508, "Drug resistance": 9.014122277824814, "Eosinophil count increased": 26.70384928505748, "Hepatic failure": 11.50809851459593, "Hepatic function abnormal": 9.703154620030972, "Hypokalaemia": 5.424385890857232, "Infection": 2.8467628129589446, "Mucormycosis": 130.36712523267298, "Multiple organ dysfunction syndrome": 9.906876627679932, "Off label use": 3.054152187353825, "Pathogen resistance": 31.156905845030607, "Pneumonia": 2.8753094547954787, "Product use in unapproved indication": 2.081380045692739, "Respiratory failure": 7.315716756677744, "Therapy non-responder": 9.20547464625073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/726.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/726.json
index ba838e43c37..ceffc9fb684 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/726.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/726.json
@@ -1 +1 @@
-{"Agonal respiration ": 378.5960489497312, "Anaemia ": 7.753643759986471, "Anaphylactic reaction ": 3.3934955734555463, "Anaphylactic shock ": 2.231083079273147, "Aplasia pure red cell ": 245.8315059291889, "Blood pressure decreased ": 4.631393462296765, "Blood pressure increased ": 3.4570393743604626, "Cardiac arrest ": 4.069832332566697, "Cardiac failure ": 4.08373523027156, "Cardio-respiratory arrest ": 3.235657699172516, "Cerebral haemorrhage ": 2.6203625704273983, "Cyanosis ": 2.059716480990238, "Death ": 7.532993355746476, "Drug hypersensitivity ": 63.10504240921421, "Drug ineffective ": 2.504344501157931, "Dyspnoea ": 2.788606025795872, "Feeling hot ": 3.396729513191999, "Flushing ": 12.91511937072492, "Fracture ": 2.00521205189836, "Gastrointestinal haemorrhage ": 2.045537022447713, "Haematocrit decreased ": 9.02569323503856, "Haemoglobin decreased ": 27.150315208530746, "Haemoglobin increased ": 35.968062055525465, "Hypersensitivity ": 2.0380517525422133, "Hypotension ": 2.242663784654157, "Iron deficiency anaemia ": 7.847782481175907, "Loss of consciousness ": 2.6975211508941954, "Marasmus ": 233.95195806552343, "Myelodysplastic syndrome ": 12.569013326754238, "Myelodysplastic syndrome with single lineage dysplasia ": 77.4415955149014, "No adverse event ": 16.87373296956922, "Pulmonary oedema ": 2.24889442074537, "Pulse absent ": 44.575794100875946, "Respiratory arrest ": 2.2219640631112245, "Respiratory distress ": 3.6647258506608034, "Reticulocyte count decreased ": 169.81047159311254, "Septic shock ": 2.2379664197970053, "Serum ferritin increased ": 12.76199881401562, "Shock ": 2.314983719551967, "Stevens-Johnson syndrome ": 2.059709091711614, "Therapeutic response decreased ": 5.085444742010496, "Therapy non-responder ": 4.787904904196162, "Throat tightness ": 5.015735851215882, "Unresponsive to stimuli ": 36.19180842117902}
\ No newline at end of file
+{"Accident at work": 53.41508211971693, "Acute kidney injury": 3.970462644515535, "Angina pectoris": 2.07171917847922, "Angina unstable": 2.4278832179268317, "Angioedema": 5.93002438327731, "Anuria": 4.070465430069324, "Apraxia": 16.188319255843574, "Atrial fibrillation": 2.293359249839364, "Atrioventricular block complete": 3.538110478822175, "Atrophic vulvovaginitis": 55.16106784639823, "Bite": 36.44493719004928, "Blood alkaline phosphatase increased": 3.5190586320899446, "Blood chloride decreased": 11.732202933256296, "Blood cholesterol abnormal": 7.818093217570179, "Blood creatine phosphokinase increased": 5.518530062263935, "Blood creatinine increased": 4.062244309404034, "Blood iron decreased": 5.280923600748479, "Blood parathyroid hormone increased": 16.67822070613794, "Blood phosphorus increased": 8.189298526655117, "Blood potassium increased": 12.64254691488062, "Blood pressure abnormal": 4.162138188571201, "Blood pressure decreased": 4.841648824676939, "Blood pressure diastolic abnormal": 10.49610307999825, "Blood pressure fluctuation": 6.198130716275901, "Blood pressure inadequately controlled": 14.110070755920894, "Blood pressure increased": 6.916470218957954, "Blood pressure systolic abnormal": 19.630022783616592, "Blood pressure systolic increased": 4.523947690889748, "Blood sodium decreased": 5.390516612964055, "Blood sodium increased": 13.962300407961903, "Blood urea increased": 7.7880270138163, "Blood uric acid increased": 6.079852143823153, "Bradycardia": 3.811649158757027, "Cardiogenic shock": 3.331409776282087, "Cerebral infarction": 2.0751201419125627, "Cholelithiasis": 2.0000507388136493, "Chromaturia": 2.0803883930497644, "Colitis ischaemic": 2.4766731733625207, "Colon cancer": 4.389184739190488, "Cough": 2.002552965395662, "Cystitis": 3.167948942080643, "Dementia": 2.3367636678301587, "Dermatitis exfoliative generalised": 2.99142010022471, "Diabetic foot": 7.003120379896103, "Diabetic nephropathy": 9.56719642005379, "Drug eruption": 4.733359356076162, "Drug-induced liver injury": 3.138556884578222, "Emphysema": 2.652321428572374, "Erythema multiforme": 2.914028653213728, "Face oedema": 2.6661602853325848, "Faeces discoloured": 2.0671097731412917, "Fall": 2.056641734452156, "Gamma-glutamyltransferase increased": 2.347468052127309, "Generalised oedema": 2.371044971549952, "Gout": 2.125469223018796, "Growth hormone deficiency": 141.42414367164525, "Gynaecomastia": 2.587408685157932, "Heart rate decreased": 2.7862177420561807, "Hepatic function abnormal": 6.409544555505026, "Hepatitis acute": 2.887395841901769, "Hepatitis fulminant": 4.730046383830578, "Hepatocellular injury": 3.5319344169338973, "Hyperkalaemia": 14.49326720902678, "Hypertension": 2.373622724552657, "Hypertensive crisis": 10.889220621899009, "Hypertonic bladder": 12.760128558653369, "Hyperuricaemia": 4.240958326105247, "Hypoglycaemia": 2.067289156562403, "Hyponatraemia": 4.029097598695937, "Hypotension": 4.558256462518918, "Hypovolaemia": 3.903907657932638, "Infarction": 5.08994259095519, "Interstitial lung disease": 5.7200275418082205, "Iron deficiency anaemia": 2.773267079866394, "Jaundice": 4.3400672641954285, "Jaundice cholestatic": 3.599469362675688, "Laryngeal oedema": 2.215224960271684, "Left ventricular hypertrophy": 5.381390153472279, "Liver disorder": 6.3990990878489695, "Loss of consciousness": 2.273015110552227, "Lung neoplasm malignant": 2.2353341957195973, "Lymphocyte stimulation test positive": 28.219296444610364, "Myocardial infarction": 2.296668461155902, "Nocturia": 3.1292894842723293, "Oedema peripheral": 2.1781223758279533, "Orthostatic hypotension": 7.421186332731648, "Pancreatic carcinoma stage III": 212.41774211152327, "Pharyngeal oedema": 5.951735112876463, "Pneumonia bacterial": 4.173568235739093, "Product physical issue": 2.74932061350575, "Product quality issue": 2.768994884163483, "Pulmonary hypoplasia": 33.597946141138486, "Rales": 2.4995400933993293, "Renal artery stenosis": 16.87768020449559, "Renal impairment": 3.9201168858816593, "Renal tubular necrosis": 2.112114062594691, "Rhabdomyolysis": 5.104241601318505, "Road traffic accident": 2.281640535556205, "Shock": 2.622901360421774, "Sinus node dysfunction": 7.238689469577108, "Sjogren's syndrome": 5.987456186707822, "Skin laceration": 2.301432890653256, "Stevens-Johnson syndrome": 2.0260853359400395, "Syncope": 2.355101912101205, "Tendonitis": 2.7736174320764237, "Therapy non-responder": 2.519448098232737, "Thrombocytopenic purpura": 5.8236097052608775, "Toxic skin eruption": 3.143755010594106}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/727.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/727.json
index 249be03d281..c8dcd14a36a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/727.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/727.json
@@ -1 +1 @@
-{"Application site erythema ": 73.8955897172656, "Application site pain ": 11.539053877987769, "Condition aggravated ": 10.170270220550512, "Dermatitis ": 22.39980999291057, "Dermatitis contact ": 68.41485373281414, "Erythema ": 27.253860281990885, "Feeling hot ": 9.760374108496348, "Flushing ": 31.52152054501875, "Hypersensitivity ": 3.3112914639899858, "Rebound effect ": 236.9391005386156, "Rosacea ": 711.5949721018367, "Skin burning sensation ": 105.16860408228771}
\ No newline at end of file
+{"Acute kidney injury": 5.897491265979695, "Angioedema": 2.5709492481470337, "Balance disorder": 2.647555381000082, "Blood potassium decreased": 8.607866497485936, "Blood pressure decreased": 3.7657814452091176, "Blood pressure increased": 2.8454845877984347, "Cough": 2.034094156453323, "Dry mouth": 4.474405118016654, "Electrolyte imbalance": 16.370008908521847, "Erectile dysfunction": 11.784280346717562, "Fall": 2.9351323163830947, "Hyperkalaemia": 8.320827121888582, "Hypertensive crisis": 13.864332829667823, "Hyperuricaemia": 56.98978011291496, "Hypokalaemia": 6.3623501141381125, "Hyponatraemia": 36.229688108395926, "Hypotension": 9.43220790462785, "Inappropriate antidiuretic hormone secretion": 15.451594909593137, "Lactic acidosis": 7.595427151077852, "Orthostatic hypotension": 14.459104903511028, "Pancreatitis": 2.8276290756533724, "Photosensitivity reaction": 10.022856636163448, "Presyncope": 8.445860528172176, "Syncope": 4.372445474212852, "Vertigo": 3.2191524161022684}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/728.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/728.json
index ff1f9691e2a..db2dbba68a4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/728.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/728.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 3.078737307373143, "Abdominal pain upper ": 2.303762379264908, "Abortion induced incomplete ": 376.5301586356688, "Alopecia ": 2.832206746671133, "Aphasia ": 20.773318408665148, "Atrial thrombosis ": 220.9642656207368, "Blister ": 5.008849940659971, "Dyskinesia ": 21.520422080572413, "Exposure during pregnancy ": 3.7550259546928393, "Inappropriate schedule of product administration ": 7.772847748160262, "Induced abortion failed ": 44.36925233704665, "Maternal exposure during pregnancy ": 9.446188138221132, "Metabolic acidosis ": 12.174774813714428, "Muscular weakness ": 6.466238838833422, "Off label use ": 2.791274438059856, "Paraesthesia oral ": 19.61731223106112, "Postpartum haemorrhage ": 274.6963063577937, "Product use in unapproved indication ": 2.3332521360094978, "Pulmonary thrombosis ": 50.67295901262548, "Small for dates baby ": 279.07197100062405, "Surgery ": 40.02432412518667, "Thrombosis ": 6.276124838980427, "Uterine rupture ": 1028.3502611416975, "Vaginal haemorrhage ": 25.645141802749496}
\ No newline at end of file
+{"Abnormal behaviour": 2.1346029689101007, "Abortion induced": 2.330625203062013, "Accidental overdose": 3.276919895094155, "Acidosis": 3.49102154682332, "Acute generalised exanthematous pustulosis": 4.00719348000182, "Acute pulmonary oedema": 7.089552682788282, "Acute respiratory distress syndrome": 4.233486961235872, "Acute respiratory failure": 2.123807371826694, "Aggression": 2.5614368868521877, "Agitation": 7.027461828253547, "Airway complication of anaesthesia": 85.73327635780471, "Altered state of consciousness": 4.247092809747, "Amino acid level increased": 115.60085864622104, "Anaesthetic complication": 17.36179230822008, "Anaesthetic complication neurological": 638.727152898888, "Anaphylactic reaction": 10.712664122511526, "Anaphylactic shock": 14.791913494924014, "Anaphylactoid reaction": 8.222547265549204, "Anaphylactoid shock": 26.21410166040369, "Anticholinergic syndrome": 19.59069455224311, "Anuria": 2.1279029565978065, "Aortic valve incompetence": 5.580270325501885, "Apgar score low": 22.053214623249666, "Apnoea": 16.42819068423923, "Apnoeic attack": 29.36131940314148, "Areflexia": 6.259141874267348, "Arteriospasm coronary": 6.970379619846817, "Aspiration": 12.897451021167164, "Atelectasis": 4.134878534193873, "Atrioventricular block": 4.919193338103243, "Autonomic nervous system imbalance": 8.421452998157308, "Blood bicarbonate decreased": 11.683967862301108, "Blood calcium decreased": 2.3048154479087346, "Blood creatine phosphokinase increased": 2.304441976292721, "Blood lactic acid increased": 3.991761117745214, "Blood magnesium decreased": 10.38566124554869, "Blood pH decreased": 11.783423627842764, "Blood pressure decreased": 3.640788566658885, "Blood pressure immeasurable": 23.64713536662452, "Blood pressure systolic decreased": 9.453365615780044, "Blood sodium increased": 12.321635370361424, "Bradycardia": 6.082982109077207, "Bradycardia foetal": 12.966123567503782, "Bradypnoea": 13.735905012667583, "Brain death": 13.218121263197473, "Brain injury": 3.784990756836197, "Brain oedema": 6.964735946214777, "Bronchoalveolar lavage abnormal": 116.7890562855435, "Bronchospasm": 10.828026404149185, "Caesarean section": 4.137306589951604, "Cardiac arrest": 8.95511331579464, "Cardio-respiratory arrest": 5.166385766023574, "Cardiogenic shock": 4.964785522051779, "Cardiomegaly": 3.990310001811636, "Cardiopulmonary failure": 4.795373189967204, "Cardiovascular insufficiency": 7.11276355366859, "Cerebral atrophy": 25.49824469367993, "Cerebral haemorrhage": 2.120408355578471, "Cerebral haemorrhage foetal": 226.17298230955137, "Cholestasis": 4.4439119738350135, "Circulatory collapse": 4.287978147928579, "Clonus": 15.325846120334685, "Coma": 6.379682462736129, "Coma scale abnormal": 6.312113461185393, "Completed suicide": 2.421464291279505, "Cyanosis": 2.123042919345576, "Deafness unilateral": 3.323954825421761, "Delayed recovery from anaesthesia": 30.525220985033773, "Delirium": 5.535893806952667, "Depressed level of consciousness": 6.009027058392195, "Dermatitis allergic": 3.119975391255279, "Device related sepsis": 18.09276142727272, "Diabetes insipidus": 10.1106456392921, "Disseminated intravascular coagulation": 3.650591722140139, "Drug abuse": 3.741359498668552, "Drug diversion": 7.725627508358282, "Drug ineffective for unapproved indication": 2.8493562516343087, "Drug interaction": 3.596576476714917, "Drug level increased": 2.1803285043453045, "Dyskinesia": 3.58663225257214, "Dystonia": 7.297579889698688, "Electrocardiogram QRS complex prolonged": 7.359511077484759, "Electrocardiogram QT prolonged": 2.3415223503601554, "Electrocardiogram ST segment elevation": 11.50615877312332, "Electrocardiogram abnormal": 3.971742243899257, "Electroencephalogram abnormal": 16.371675420703603, "Encephalopathy": 4.751134577615279, "Endotracheal intubation": 5.454695916300365, "Exposure during pregnancy": 2.3599133499654457, "Exposure via breast milk": 2.167705637984263, "Extensor plantar response": 28.576773696516508, "Extrasystoles": 2.382716820685609, "Fibrinolysis": 231.0603295074856, "Foetal death": 7.8622113470239485, "Foetal exposure during delivery": 32.37601590793237, "Foetal exposure during pregnancy": 4.222222560598248, "Foetal growth restriction": 14.828455228149242, "Generalised tonic-clonic seizure": 5.03831189883264, "Grimacing": 42.87349808881051, "Haemodynamic instability": 18.68865778039921, "Hallucination": 3.127064192882801, "Heart rate decreased": 4.694825161932841, "Hepatic cytolysis": 3.158439948107999, "Hiccups": 2.820123927446156, "Hydrothorax": 21.10657414664368, "Hypercapnia": 25.766973629773883, "Hyperreflexia": 3.801107260634944, "Hyperthermia": 6.093990597904907, "Hyperthermia malignant": 47.17248476201075, "Hypertonia": 8.425348648457915, "Hypopnoea": 4.0205013864427706, "Hypotension": 6.599711500402772, "Hypothermia": 3.0008491981819256, "Hypotonia": 2.682165010714514, "Hypoventilation": 31.46657764290041, "Hypovolaemic shock": 5.577473283304134, "Hypoxia": 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"Miosis": 5.535107337718267, "Mononucleosis syndrome": 226.56864166226225, "Movement disorder": 3.279379380682679, "Multiple organ dysfunction syndrome": 2.6501403556387624, "Multiple-drug resistance": 10.668913265310731, "Mumps": 18.370669769459653, "Muscle rigidity": 5.451503488663443, "Mydriasis": 5.78200435924204, "Myoclonus": 7.980450153190722, "Nephrogenic diabetes insipidus": 7.827812131677235, "Nerve injury": 2.603320472459751, "Nervous system disorder": 2.526573055262931, "Normal newborn": 4.362808729032698, "Nystagmus": 18.001340418123906, "Oliguria": 3.167949903410463, "Orthopnoea": 5.371866614092294, "Overdose": 3.853949001975022, "Oxygen saturation abnormal": 11.045527286318029, "Oxygen saturation decreased": 10.081567897509444, "PCO2 increased": 88.87676237242174, "PO2 increased": 67.08114236444877, "Paradoxical drug reaction": 32.845014609609585, "Partial seizures": 9.501633303022958, "Pneumothorax": 2.816640068208496, "Poisoning": 6.5471491633835806, "Poisoning deliberate": 8.141953088597667, "Poor feeding infant": 17.712209285861192, "Post procedural haemorrhage": 2.403334014390584, "Postoperative delirium": 40.881192247353525, "Potentiating drug interaction": 4.559326478525187, "Premature baby": 2.110307346248842, "Premature delivery": 2.266586478328162, "Product administered to patient of inappropriate age": 4.787728912960708, "Product contamination physical": 44.26581189268449, "Propofol infusion syndrome": 15.998029516098596, "Psychomotor hyperactivity": 5.473343443014742, "Pulmonary hypertensive crisis": 82.22632099169203, "Pulmonary oedema": 2.899131160840824, "Pulmonary toxicity": 2.897872365273095, "Pulmonary vascular disorder": 73.88885032846771, "Pulse absent": 11.997571134563415, "Pulseless electrical activity": 15.489969248305824, "Pupillary reflex impaired": 17.40187898653534, "Quadriplegia": 12.418059419626864, "Rash maculo-papular": 2.582554477679923, "Renal ischaemia": 56.06908197653861, "Respiration abnormal": 4.332763125685568, "Respiratory acidosis": 12.830893590626342, "Respiratory arrest": 12.273394013827234, "Respiratory depression": 30.64796143763205, "Respiratory disorder": 2.538642061891472, "Respiratory distress": 4.207744039114366, "Respiratory failure": 5.498225988630641, "Respiratory rate decreased": 6.054258652488604, "Respiratory rate increased": 6.4124608686099975, "Respiratory symptom": 6.967604002117082, "Restlessness": 2.085828060093996, "Resuscitation": 10.406395131228765, "Rhabdomyolysis": 3.749916545922946, "Salivary hypersecretion": 2.9650945843901644, "Schizencephaly": 345.1395535746629, "Sedation": 7.711292703832431, "Sedation complication": 31.10289908395021, "Seizure": 2.6460250120732183, "Seizure like phenomena": 24.6534542718135, "Serotonin syndrome": 2.818800052393589, "Sinus tachycardia": 6.823320371903463, "Somnolence": 2.119493683287743, "Status epilepticus": 15.098614578229393, "Stillbirth": 8.01891289813498, "Stress cardiomyopathy": 11.47784632786579, "Stupor": 3.6306018416540846, "Substance abuse": 2.8198012826184016, "Sudden death": 2.672184478225242, "Tachycardia": 3.3841932387152127, "Tachyphylaxis": 62.386123568211865, "Tachypnoea": 2.624312019975212, "Therapeutic response decreased": 2.3630673154448174, "Therapy change": 11.152246920962847, "Tonic convulsion": 6.4241454497223245, "Torsade de pointes": 6.30072403553569, "Toxicity to various agents": 4.682328346999396, "Tricuspid valve disease": 56.4552248947429, "Type I hypersensitivity": 7.417708927828644, "Unresponsive to stimuli": 9.04578037149738, "Unwanted awareness during anaesthesia": 112.91342737985308, "Urinary tract candidiasis": 108.9581473077792, "Ventricular extrasystoles": 4.772265392530856, "Ventricular fibrillation": 5.541536639818625, "Ventricular tachycardia": 3.272358133717429, "Withdrawal syndrome": 4.03602798703815, "Wrong patient received product": 7.322031489116171}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/729.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/729.json
index 0c526bae131..5a49b3c3c3c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/729.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/729.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 143.74734735871854, "Central hypothyroidism ": 1979.9628794670311, "Disease progression ": 7.289522860348299, "Hypothyroidism ": 12.78136320557146, "Malignant neoplasm progression ": 16.095815953969478, "Mineralocorticoid deficiency ": 28927.234211841896, "Off label use ": 14.430669970603438, "Product use in unapproved indication ": 5.6574886459979}
\ No newline at end of file
+{"Acute myeloid leukaemia": 31.715570770834983, "Acute myeloid leukaemia recurrent": 193.72812723359, "Ascites": 12.16445840759628, "Drug interaction": 2.5009466553780597, "Electrocardiogram QT prolonged": 12.564313883995508, "Febrile neutropenia": 16.53198203611618, "Malignant neoplasm progression": 6.537038938722183, "Neutropenia": 2.7958137673579446, "Sepsis": 6.140103921427586, "Septic shock": 10.536515340003334, "Thrombocytopenia": 4.082087098361945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/73.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/73.json
index 194dace53e3..e8e555c2dc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/73.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/73.json
@@ -1 +1 @@
-{"Abscess ": 3.4088407597988524, "Adrenal insufficiency ": 10.160710950054884, "Alpha tumour necrosis factor increased ": 903.530592265182, "Alveolar proteinosis ": 135.4513938645052, "Ankle arthroplasty ": 115.11539136959284, "Ankylosing spondylitis ": 2.260988298120851, "Anti-cyclic citrullinated peptide antibody positive ": 5.267850886950919, "Anti-neutrophil cytoplasmic antibody positive vasculitis ": 10.334892715896435, "Antibody test positive ": 51.39037263212762, "Apparent death ": 699.1225933891851, "Arthritis ": 2.9993302429471487, "Arthrodesis ": 214.09990399409415, "Arthropathy ": 13.007647934214392, "Aspartate aminotransferase ": 100.15806602655712, "Autoinflammatory disease ": 238.03094422202145, "Axial spondyloarthritis ": 173.9816138466296, "Back disorder ": 2.0634008955343472, "Barotrauma ": 647.1328900046018, "Basal cell carcinoma ": 3.061743127016584, "Blister rupture ": 32.52902958506136, "Blood glucose fluctuation ": 2.1190273500288237, "Blood immunoglobulin A increased ": 66.24806939675368, "Blood pressure diastolic decreased ": 8.832667405605523, "Blood pressure fluctuation ": 5.194217442138185, "Blood pressure systolic abnormal ": 14.513795267847357, "Blood pressure systolic decreased ": 6.417537827206794, "Blood test abnormal ": 3.0208704222921985, "Blood uric acid increased ": 3.7484852172391294, "Body height below normal ": 281.1872421712064, "Body tinea ": 165.77864200420166, "Bone density abnormal ": 3.302796236996701, "Bone density increased ": 86.04486263980219, "Bone erosion ": 4.033779177202423, "Bone marrow failure ": 2.450338327596717, "C-reactive protein abnormal ": 30.275370316116856, "C-reactive protein increased ": 11.551156548490807, "Cataract ": 2.676169655529511, "Cholecystitis acute ": 8.412853877057474, "Chondrocalcinosis ": 86.67267192740884, "Clear cell renal cell carcinoma ": 17.51310980137076, "Clubbing ": 169.47928810488636, "Coeliac disease ": 2.747239050458302, "Complications of bone marrow transplant ": 91.57334779058392, "Condition aggravated ": 2.6571572716387206, "Contraindicated product administered ": 21.662319919061044, "Coordination abnormal ": 2.3930557784256137, "Cytokine release syndrome ": 4.4683023572488585, "Deep vein thrombosis ": 6.951022350424736, "Deformity ": 94.89663659365397, "Diverticulitis ": 30.81329001782712, "Drug hypersensitivity ": 11.26621782250936, "Drug ineffective ": 5.274345155357734, "Drug intolerance ": 10.596363906232725, "Drug specific antibody ": 41.92979281788055, "Drug specific antibody present ": 33.578332789708206, "Drug use disorder ": 4.46261842793169, "Endodontic procedure ": 56.488394481051664, "Febrile infection-related epilepsy syndrome ": 512.0796695649108, "Feeling abnormal ": 2.216047695579872, "Fine motor skill dysfunction ": 8.751303192217922, "Finger deformity ": 5.857649107687596, "Foot deformity ": 16.127376329404633, "Foot operation ": 16.853684220720293, "Gastroenteritis viral ": 2.91403498341792, "Gastrointestinal perforation ": 13.037557209225357, "Glucose tolerance impaired ": 22.199137176182617, "Grip strength decreased ": 4.428822769221017, "Haemodynamic instability ": 3.1532712800465563, "Haemoglobin decreased ": 2.951978272253908, "Haemophagocytic lymphohistiocytosis ": 17.560226980134424, "Hair follicle tumour benign ": 239.867692138681, "Hand deformity ": 6.272781466344495, "Heart rate decreased ": 2.213430083068383, "Hepatosplenic T-cell lymphoma ": 129.96523550269524, "Hepatosplenomegaly ": 6.098629660157629, "Hepatotoxicity ": 21.505856923663856, "Herpes zoster ": 2.848264339664613, "Human antichimeric antibody positive ": 327.4727936270185, "Hyperlipidaemia ": 2.091261301758052, "Hyperparathyroidism secondary ": 59.985525982592, "Hypomagnesaemia ": 6.48349124968415, "Ill-defined disorder ": 20.73302986042013, "Impaired healing ": 2.705227249070439, "Impaired quality of life ": 13.052524413582692, "Impaired work ability ": 4.63505431041742, "Infection ": 3.525540576911925, "Infection susceptibility increased ": 6.093063323525795, "Inhibitory drug interaction ": 10.521451883489991, "Injection site hypersensitivity ": 6.726597611740453, "Injection site reaction ": 2.663315037963486, "Intentional product use issue ": 9.21850463348562, "Interleukin level increased ": 106.50186381140963, "Interstitial lung disease ": 5.930703949589351, "Intestinal sepsis ": 1036.883909789384, "Jaw fracture ": 9.31713815930538, "Joint arthroplasty ": 185.2704447919268, "Joint destruction ": 14.494195701865946, "Joint effusion ": 5.571539098105633, "Joint injury ": 10.07924266986508, "Joint range of motion decreased ": 2.9220206063504315, "Joint swelling ": 13.605380101333427, "Juvenile idiopathic arthritis ": 70.2697565729198, "Knee arthroplasty ": 27.68503273740249, "Localised infection ": 4.99459380194368, "Loss of consciousness ": 4.989524303724422, "Lymphoproliferative disorder ": 9.834574828168238, "Magnetic resonance imaging head abnormal ": 10.20912020746489, "Mobility decreased ": 17.891113336828145, "Monocyte chemotactic protein-1 increased ": 4518.732904412501, "Multiple-drug resistance ": 11.218753785241592, "Musculoskeletal disorder ": 47.896622089975885, "Musculoskeletal pain ": 16.16478557257648, "Myocardial infarction ": 2.451164047016015, "Neck pain ": 6.03337410997935, "New onset refractory status epilepticus ": 104.17914485032036, "No adverse event ": 9.29073798697564, "Nodule ": 21.314026062593165, "Obesity ": 7.672484533025304, "Off label use ": 3.588936772623088, "Pain ": 3.0632426423754064, "Photosensitivity reaction ": 13.697778504350682, "Pleural adhesion ": 88.2559498903586, "Pneumonia lipoid ": 108.9085412381968, "Polyarteritis nodosa ": 39.2025044059492, "Polyarthritis ": 12.56571645821245, "Poor quality sleep ": 8.115974618438939, "Post procedural contusion ": 149.62107970785385, "Prescribed underdose ": 16.092328740094636, "Psoriasis ": 2.0365221602968604, "Pulmonary embolism ": 5.026160884739034, "Pulmonary fibrosis ": 8.087008746306887, "Pulmonary thrombosis ": 56.50407474955294, "Quality of life decreased ": 9.834294971345996, "Red blood cell sedimentation rate abnormal ": 162.28748150609337, "Red blood cell sedimentation rate decreased ": 73.31830171228482, "Red blood cell sedimentation rate increased ": 57.61749784620742, "Renal failure ": 2.5998176343247703, "Rheumatoid arthritis ": 14.97446116101984, "Rheumatoid factor positive ": 19.394685961484104, "Sacroiliitis ": 41.80354409344876, "Sciatica ": 2.452075853294096, "Sepsis ": 4.690349100202264, "Septic shock ": 3.497504590144707, "Serum ferritin increased ": 9.350318386341488, "Shoulder arthroplasty ": 115.23191269231651, "Skin fissures ": 8.410424845715989, "Smear cervix abnormal ": 72.09996219437022, "Spinal stenosis ": 2.73631308061473, "Splenomegaly ": 3.927239345850542, "Spondyloarthropathy ": 116.03042657379598, "Stent placement ": 13.54151920680213, "Still's disease ": 38.56846597662207, "Stomatitis ": 3.225649236251964, "Syncope ": 2.257386136910581, "Synovial cyst ": 8.61115687772726, "Synovitis ": 13.943260613063604, "T-cell lymphoma ": 28.901442041962586, "Terminal state ": 76.00822313181803, "Therapeutic product effect decreased ": 16.240962556610636, "Therapeutic product effect incomplete ": 10.216341338857733, "Therapy non-responder ": 3.1689852155767, "Thrombosis ": 3.936072121391616, "Tooth disorder ": 4.6749299971638365, "Toothache ": 3.795449975751888, "Treatment failure ": 12.741733092693355, "Type IV hypersensitivity reaction ": 14.933718151158471, "Ulcer ": 5.846560033257857, "Vitamin D decreased ": 17.13515439897042, "Wheelchair user ": 7.153326826585732}
\ No newline at end of file
+{"Anaemia": 4.594814524997642, "Bradycardia": 7.792058399869827, "Drug ineffective": 2.344856721340219, "Drug intolerance": 9.591486456677035, "Dysaesthesia": 73.24290938521547, "Haemoglobin decreased": 11.317748609915052, "Myelofibrosis": 245.4323693937629, "Paraesthesia": 2.3405870967337536, "Platelet count decreased": 6.713019868553475, "Platelet count increased": 70.73577353593751, "Sedation": 29.8445940125878, "Somnolence": 2.7408445479974484, "Splenomegaly": 66.15655087495634, "Vertigo": 5.578272728764781}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/730.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/730.json
index e4eebe5fe37..51da981dd11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/730.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/730.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 4.915194563394945, "Anaphylactic shock ": 2.9126298870710503, "Angina pectoris ": 3.6450654210813416, "Blood glucose abnormal ": 21.036016878035117, "Blood glucose decreased ": 7.097214063538854, "Blood glucose fluctuation ": 19.7366608186142, "Blood glucose increased ": 21.191317283004476, "Coma ": 3.123999946806339, "Device failure ": 29.74375471385549, "Diabetes mellitus inadequate control ": 24.90666304953643, "Diabetic coma ": 46.458681894083526, "Diabetic foot ": 85.83869103505633, "Diabetic ketoacidosis ": 27.385474127679416, "Gangrene ": 31.619309296179427, "Glycosylated haemoglobin increased ": 6.568116180033895, "Hyperglycaemia ": 57.06103805491388, "Hypersensitivity ": 4.453007068751582, "Hypoglycaemia ": 34.55391722451432, "Hypoglycaemic coma ": 117.8720885637614, "Injection site abscess ": 68.76364098067428, "Injection site reaction ": 5.044178056233551, "Liquid product physical issue ": 46.19583586412519, "Maternal exposure during pregnancy ": 3.0016215913852964, "Overdose ": 2.180112163946692, "Pallor ": 3.961992413953552, "Product quality issue ": 7.925849101663631, "Product storage error ": 8.659812233775915, "Treatment noncompliance ": 5.101551800741766, "Wrong technique in product usage process ": 4.966540947246091}
\ No newline at end of file
+{"Hypersensitivity myocarditis": 56617.2757639899}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/731.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/731.json
index 84102e88e8f..d320f2cb233 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/731.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/731.json
@@ -1 +1 @@
-{"Abnormal faeces ": 2.2191072859617997, "Acute disseminated encephalomyelitis ": 4.90569215227574, "Administration site erythema ": 3.4670877470531285, "Allergy to metals ": 126.83694354529229, "Antibody test negative ": 20.75810856637325, "Apathy ": 2.9328853250945754, "Aphthous ulcer ": 2.1865439005874423, "Apnoea ": 4.161526218099412, "Application site urticaria ": 8.755671041850686, "Ataxia ": 2.0973131117675377, "Autism spectrum disorder ": 7.923270583640497, "Body temperature decreased ": 6.548659433986612, "Body temperature increased ": 3.589282046461688, "Breath holding ": 51.02515718285372, "Catarrh ": 18.710368379659894, "Conjunctival hyperaemia ": 2.807183475292194, "Conjunctivitis ": 18.754667283918312, "Cough ": 3.60011221592302, "Crying ": 49.19719809230512, "Cyanosis ": 3.855174341627112, "Cyanosis central ": 24.479392325066605, "Decreased appetite ": 3.180327101272641, "Delirium febrile ": 29.912972887841025, "Dermatitis atopic ": 4.177515936600098, "Drooling ": 6.935784455908836, "Ear infection ": 7.379085670287184, "Ear swelling ": 2.030182087393097, "Ecchymosis ": 2.269324918225508, "Eczema ": 3.418287827688867, "Enanthema ": 6.144632904899591, "Encephalitis ": 2.413283661116198, "Erythema of eyelid ": 2.844969311147835, "Exanthema subitum ": 44.1801676623634, "Exposure via skin contact ": 5.141620923760652, "Extensive swelling of vaccinated limb ": 2.941809985853985, "Eye discharge ": 2.7405085538727927, "Eye inflammation ": 5.861368482614195, "Eye movement disorder ": 3.96700055365045, "Febrile convulsion ": 61.82734470855022, "Gastroenteritis ": 2.365124807172967, "Gaze palsy ": 15.768668091530634, "Gianotti-Crosti syndrome ": 53.6910382152705, "Head banging ": 14.447342841230578, "Henoch-Schonlein purpura ": 4.151781861430987, "Hyperaemia ": 2.5340654820322897, "Hyperpyrexia ": 61.9294216501321, "Hypertonia ": 7.869019385311396, "Hyporesponsive to stimuli ": 4.631635040947092, "Hypotonia ": 4.534406081600937, "Hypotonic-hyporesponsive episode ": 36.14993408742078, "Immune thrombocytopenia ": 6.732366864583718, "Infantile back arching ": 73.2441974743109, "Infection susceptibility increased ": 2.883652658598969, "Injected limb mobility decreased ": 2.752424731916186, "Injection site discomfort ": 2.01908748162016, "Injection site erythema ": 7.60287510516651, "Injection site inflammation ": 4.126982063857407, "Injection site oedema ": 2.453367024156379, "Injection site rash ": 4.624084386621269, "Injection site swelling ": 2.586641463528682, "Injection site vesicles ": 11.23907686264527, "Injection site warmth ": 2.2419999128532435, "Irritability ": 4.687593131372768, "Irritability postvaccinal ": 593.8582125548261, "Juvenile idiopathic arthritis ": 3.620966937599512, "Laryngitis ": 3.3423246520516656, "Listless ": 78.48819994934202, "Local reaction ": 2.94402812755673, "Lymphadenitis ": 3.674532324759927, "Lymphadenopathy ": 2.980412633495709, "Maternal exposure before pregnancy ": 11.285844510184155, "Measles ": 43.75512412166614, "Measles antibody negative ": 138.13164024857514, "Measles post vaccine ": 137.43701108319576, "Meningism ": 3.955422373628032, "Moaning ": 7.823572444570948, "Mumps ": 21.46837729829788, "Mumps antibody test negative ": 100.51277911411076, "Nasopharyngitis ": 9.713547105587658, "No adverse event ": 2.656756481863554, "Noninfective sialoadenitis ": 14.41155945541538, "Oligodipsia ": 70.21447117876387, "Opisthotonus ": 4.972029947016519, "Oral mucosal eruption ": 5.925652820205065, "Orchitis ": 9.51702650626466, "Otitis media ": 14.109401929844422, "Otitis media acute ": 19.158406091721755, "Pallor ": 5.93730885954629, "Papule ": 2.9653925426285235, "Parotid gland enlargement ": 82.10370106574, "Parotitis ": 34.78395360307713, "Petechiae ": 5.56932217385685, "Pharyngeal erythema ": 19.45851738799934, "Pharyngitis ": 8.14258624957039, "Poor quality sleep ": 2.941150128798684, "Postictal state ": 4.896427972657276, "Pyrexia ": 6.767609389863074, "Rash ": 4.779050063164862, "Rash erythematous ": 4.232976187507645, "Rash macular ": 17.88957498348627, "Rash maculo-papular ": 4.380605918029413, "Rash morbilliform ": 223.28548270895348, "Rash papular ": 12.78169540931529, "Rash pruritic ": 2.410353082935357, "Rash rubelliform ": 506.8084816369881, "Rash vesicular ": 26.97762269354571, "Reaction to excipient ": 26.152224523580703, "Respiration abnormal ": 4.477757732942134, "Respiratory tract infection ": 2.498024128645964, "Restlessness ": 4.237835274856017, "Rhinitis ": 5.836410905507463, "Rhinorrhoea ": 2.561623267502285, "Rubella ": 40.41853472716425, "Rubella antibody negative ": 90.74842407454018, "Salivary gland enlargement ": 4.84422517230094, "Salivary gland pain ": 12.110602093909923, "Scratch ": 28.134086092751165, "Screaming ": 61.73822130358348, "Skin warm ": 3.535789791234909, "Skin wound ": 77.01037602335396, "Somnolence ": 3.481136738876428, "Speech disorder developmental ": 5.725840820502728, "Staring ": 9.926845169763938, "Strabismus ": 6.805512796656956, "Subglottic laryngitis ": 33.520679541267015, "Swelling face ": 2.052452521328159, "Syringe issue ": 4.106476847441487, "Tearfulness ": 2.955086151459067, "Thirst decreased ": 10.518567064610794, "Thrombocytopenic purpura ": 2.4357431484741, "Tonic clonic movements ": 2.942719119286678, "Tonic convulsion ": 2.3288767526889287, "Tonsillar hypertrophy ": 3.825523691449448, "Tonsillitis ": 5.315952342238215, "Tympanic membrane hyperaemia ": 60.92190509399489, "Upper respiratory tract infection ": 2.375498359674113, "Urticaria ": 3.3343229671625427, "Vaccination complication ": 12.360323281803293, "Vaccination error ": 7.308917758624931, "Vaccination site discolouration ": 42.60356141210312, "Vaccination site dryness ": 188.5578073697158, "Vaccination site eczema ": 110.94639226178272, "Vaccination site erythema ": 3.3889141175212, "Vaccination site granuloma ": 308.6592987071166, "Vaccination site hypertrichosis ": 300.3033382253412, "Vaccination site hypertrophy ": 179.99183316614966, "Vaccination site irritation ": 37.3490613321216, "Vaccination site nodule ": 19.86285678898617, "Vaccination site oedema ": 6.734524941574374, "Vaccination site pruritus ": 6.016484327402222, "Vaccination site rash ": 6.036000036173157, "Vaccination site reaction ": 4.148795048017177, "Vaccination site scar ": 34.217966005721514, "Vaccination site swelling ": 5.4202125544230855, "Vaccination site urticaria ": 3.3470804440743254, "Vaccination site vesicles ": 87.9787336902428, "Viral infection ": 2.170415844695514, "Vomiting ": 2.3333715961180763, "Vomiting projectile ": 3.1169022698731026}
\ No newline at end of file
+{"Abdominal pain upper": 2.0797347128692896, "Adenoma benign": 142.36102134351103, "Angiopathy": 10.238481164956204, "Blood calcium abnormal": 155.49474724300757, "Blood calcium decreased": 39.458404272688206, "Blood calcium increased": 74.11910324376421, "Blood parathyroid hormone abnormal": 853.2897477860769, "Blood parathyroid hormone decreased": 68.61286924326238, "Blood parathyroid hormone increased": 881.6131772894765, "Blood phosphorus decreased": 22.28517840000421, "Blood phosphorus increased": 26.900931614474924, "Bone pain": 3.456732685835604, "Brown tumour": 2998.3560143191157, "Calciphylaxis": 153.1362978240474, "Cardiac failure": 4.138008910826263, "Dementia": 3.6802490962045935, "Dialysis": 8.007333561418653, "Drug intolerance": 13.614901194244338, "Dysphagia": 10.24079618002619, "Electrocardiogram QT prolonged": 2.017175315794044, "Eosinophilia": 2.0786496488732835, "Epilepsy": 2.533047565713162, "Erectile dysfunction": 3.4881885459392232, "Gait inability": 3.216013705819196, "Gastric haemorrhage": 5.117987947110145, "Gastrointestinal disorder": 9.902747864068594, "Gastrointestinal tube insertion": 167.58058502170368, "Gastrostomy": 155.17940999063666, "General physical health deterioration": 2.3062790571342644, "Hospitalisation": 3.356559704483112, "Hungry bone syndrome": 1741.8962004735863, "Hypercalcaemia": 58.74948521661065, "Hyperkalaemia": 2.333634109414389, "Hyperparathyroidism": 27.879968664447784, "Hyperphosphataemia": 21.13003939953836, "Hypertensive crisis": 4.509104610279337, "Hypocalcaemia": 164.03636205488937, "Hypophosphataemia": 11.28326852222456, "Malnutrition": 6.854318975706754, "Muscle spasms": 2.4120189069019107, "Nausea": 2.131879094870109, "Nephrocalcinosis": 80.32732908656111, "Nephrolithiasis": 2.401741344584049, "Off label use": 2.487968426238915, "Parathyroid disorder": 147.73537481203763, "Parathyroid tumour benign": 487.32319843541393, "Parathyroid tumour malignant": 819.8834597316322, "Parathyroidectomy": 988.230776727609, "Premature delivery": 5.409134156361651, "Purpura": 3.4626281311087963, "Rash pruritic": 3.789961535698939, "Renal transplant": 47.82512990416674, "Skin ulcer": 4.911313439209337, "Surgery": 2.374930569350868, "Tetany": 45.6760341801204, "Therapeutic product effect incomplete": 2.550045975516255, "Therapy non-responder": 5.92677545313313, "Transaminases increased": 3.110196568457165, "Transplant": 44.51280032992484, "Treatment noncompliance": 5.726543965145249, "Underdose": 11.165910865547437, "Unevaluable event": 4.113144049503172, "Vomiting": 2.294164046982421, "Wrong technique in product usage process": 6.851611353012378}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/732.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/732.json
index 3b04915a7eb..62a8e258946 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/732.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/732.json
@@ -1 +1 @@
-{"Blood glucose increased ": 7.70676283649294, "Constipation ": 5.630627601128025, "Decreased appetite ": 3.348974610353619, "Hypoglycaemia ": 10.871861929520716, "Pancreatitis ": 12.105980806309844}
\ No newline at end of file
+{"Altered state of consciousness": 5.39633365741133, "Atrial fibrillation": 2.1079871469377065, "Blood pressure increased": 6.980326744174773, "Constipation": 3.633571707781436, "Drug interaction": 2.963879047645045, "Dry mouth": 4.327617987246495, "Dysuria": 12.844730137379438, "Hyperammonaemia": 30.185213718404963, "Hypercholesterolaemia": 17.775597585053816, "Hypertension": 7.971605781381247, "Implant site extravasation": 367.6303099999968, "Incorrect route of product administration": 8.5014818066818, "Intentional product misuse": 3.649053886918591, "Lumbar vertebral fracture": 66.75008605453684, "Muscle spasms": 2.885954298210821, "Muscle spasticity": 25.36512449452459, "Narcolepsy": 111.92070764111224, "Neuropathy peripheral": 2.970140173003276, "Osteoporosis": 2.106147722018445, "Palpitations": 4.400537275479096, "Plicated tongue": 426.50703372673775, "Pollakiuria": 8.62787136213413, "Radial nerve injury": 1483.774764809838, "Rectal prolapse": 320.3578260631208, "Restless legs syndrome": 13.378735557660166, "Rosacea": 69.51356078794029, "Rotator cuff syndrome": 25.548840965612587, "Spinal compression fracture": 29.39997681632112, "Tachycardia": 4.262351432035387, "Ulnar nerve injury": 918.679257440768, "Urinary retention": 24.650958829031502, "Urinary tract infection": 7.128593923958391, "Urinary tract infection bacterial": 113.56636034178511, "Vitamin B6 deficiency": 1151.6607132013544}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/733.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/733.json
index dbe7066a9be..00070e564a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/733.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/733.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.8812252249388832, "Abdominal pain upper ": 2.458505551882922, "Accidental overdose ": 10.739194637913451, "Accidental underdose ": 331.37723142486703, "Asthenia ": 2.0222717689019443, "Back pain ": 4.878319875407518, "Blood pressure increased ": 2.014197915241601, "Bone pain ": 4.431744975003668, "Condition aggravated ": 2.057962821253692, "Dizziness ": 3.0104961643709407, "Dyspepsia ": 3.8862109221233063, "Hypercalcaemia ": 21.41948279786065, "Injection site erythema ": 7.8839659616020095, "Injection site haematoma ": 26.99942879771171, "Muscle spasms ": 5.74445811752924, "Nausea ": 2.0920516768185573, "Pain in extremity ": 3.482328270930943, "Palpitations ": 2.849534765575867, "Peripheral swelling ": 2.0284355272018013, "Poor quality product administered ": 46.00860432469364, "Product dose omission issue ": 2.2077498776996367, "Tachycardia ": 3.3846088669653067, "Urinary incontinence ": 9.093557188303851, "Vertigo ": 4.008758195843696, "Weight increased ": 2.946213359181612, "Wrong technique in device usage process ": 169.257777761374}
\ No newline at end of file
+{"Somnolence": 6.107288314931832}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/734.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/734.json
index 64442494cb1..8b52d0d3365 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/734.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/734.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 5.140314491514364, "Acute pulmonary oedema ": 4.294321954024987, "Alanine aminotransferase increased ": 7.750640114159855, "Arrhythmia ": 5.199257544728525, "Aspartate aminotransferase increased ": 7.897331596603005, "Atrial fibrillation ": 42.74937789232369, "Atrial flutter ": 27.74035632452737, "Blood alkaline phosphatase increased ": 7.366273034055711, "Blood bilirubin increased ": 6.128848835164764, "Blood creatinine increased ": 10.203298766751136, "Blood potassium increased ": 2.5343356117869105, "Blood thyroid stimulating hormone increased ": 4.8979461643180615, "Blood urea increased ": 3.67620570405038, "Bradycardia ": 5.644514539408192, "Brain natriuretic peptide increased ": 17.529504878493565, "Cardiac arrest ": 2.258779567346792, "Cardiac failure ": 10.699500476481788, "Cardiac failure chronic ": 10.43157828006213, "Cardiac failure congestive ": 8.483531432182094, "Cardiac flutter ": 3.7966228865027967, "Cholestatic liver injury ": 21.13172429581888, "Chromaturia ": 3.3400013365444763, "Coagulopathy ": 2.6557711681417056, "Condition aggravated ": 2.122456518787383, "Drug interaction ": 3.369512456082493, "Drug-induced liver injury ": 2.168802890220258, "Dyspnoea ": 2.73770514145612, "Dyspnoea exertional ": 3.020335282606203, "Ejection fraction decreased ": 8.172417815673962, "Electrocardiogram QT prolonged ": 9.647649004262677, "Electrocardiogram abnormal ": 3.2559949144933698, "Emphysema ": 4.678500418194788, "Extrasystoles ": 6.433265702433401, "Fluid retention ": 2.590595479182258, "Gamma-glutamyltransferase increased ": 13.096070626026156, "Gastrointestinal disorder ": 2.347478014591894, "Glomerular filtration rate decreased ": 10.712231050801597, "Heart rate decreased ": 10.769817329415172, "Heart rate increased ": 3.281542336909132, "Heart rate irregular ": 6.985750944358415, "Hepatic enzyme increased ": 4.548486744941788, "Hepatic failure ": 5.437816619526552, "Hepatitis ": 3.08676594123693, "Hepatitis acute ": 3.964794264298266, "Hepatitis toxic ": 6.139875882219048, "Hepatocellular injury ": 59.08653909835128, "Hepatotoxicity ": 2.2396029478194133, "Hyperthyroidism ": 6.79952728465395, "Hypertransaminasaemia ": 2.3460573106831637, "International normalised ratio abnormal ": 8.62087862811712, "International normalised ratio decreased ": 4.887511920054617, "International normalised ratio increased ": 14.238108353615944, "Interstitial lung disease ": 2.251515553064867, "Jaundice ": 3.908589244910284, "Left ventricular failure ": 10.09203072065948, "Liver function test abnormal ": 5.79210362936562, "Liver function test increased ": 6.135229458683927, "Liver injury ": 3.457507176451214, "Long QT syndrome ": 11.484943071370012, "Lung disorder ": 2.1862765197534446, "Lung infiltration ": 5.005714737087952, "Mixed liver injury ": 10.017366773863175, "Oedema ": 3.054920461652236, "Oedema peripheral ": 4.365051480602233, "Papilloedema ": 4.683874972733009, "Pericardial effusion ": 2.284978435869312, "Photosensitivity reaction ": 6.33796335013457, "Pleural effusion ": 2.12957804766806, "Polyneuropathy ": 2.378831802044324, "Prothrombin time prolonged ": 2.7897714157547737, "Pulmonary congestion ": 3.612147838508995, "Pulmonary fibrosis ": 8.012815510561927, "Pulmonary oedema ": 3.857883659075641, "Pulmonary toxicity ": 8.409473394434361, "Sinus bradycardia ": 4.171222645077596, "Sudden cardiac death ": 8.523491933733446, "Sudden death ": 3.38538492458209, "Torsade de pointes ": 13.64594892288073, "Transaminases increased ": 10.02822063539033, "Underdose ": 9.33628254728198, "Ventricular extrasystoles ": 8.343785143255133, "Ventricular fibrillation ": 7.301459660059155, "Ventricular tachycardia ": 15.582914583588828, "Weight increased ": 3.217711318469331, "Wrong technique in product usage process ": 2.202025732545953}
\ No newline at end of file
+{"Agonal respiration": 378.5960489497312, "Anaemia": 7.753643759986471, "Anaphylactic reaction": 3.3934233926249253, "Anaphylactic shock": 2.231083079273147, "Aplasia pure red cell": 245.8315059291889, "Blood pressure decreased": 4.631242962503894, "Blood pressure increased": 3.45697864205835, "Cardiac arrest": 4.069832332566697, "Cardiac failure": 4.083362061742712, "Cardio-respiratory arrest": 3.235657699172516, "Cerebral haemorrhage": 2.6203625704273983, "Cyanosis": 2.059332255584263, "Death": 7.532993355746476, "Drug hypersensitivity": 63.10504240921421, "Drug ineffective": 2.5043259751808367, "Dyspnoea": 2.788564563249396, "Feeling hot": 3.396729513191999, "Flushing": 12.91511937072492, "Fracture": 2.00521205189836, "Gastrointestinal haemorrhage": 2.045537022447713, "Haematocrit decreased": 9.02569323503856, "Haemoglobin decreased": 27.150315208530746, "Haemoglobin increased": 35.968062055525465, "Hypersensitivity": 2.0380517525422133, "Hypotension": 2.2426119080817744, "Iron deficiency anaemia": 7.844994036596608, "Loss of consciousness": 2.697389044514848, "Marasmus": 233.95195806552343, "Myelodysplastic syndrome": 12.569013326754238, "Myelodysplastic syndrome with single lineage dysplasia": 77.4415955149014, "No adverse event": 16.87373296956922, "Pulmonary oedema": 2.248599058525283, "Pulse absent": 44.575794100875946, "Respiratory arrest": 2.2219640631112245, "Respiratory distress": 3.6647258506608034, "Reticulocyte count decreased": 169.81047159311254, "Septic shock": 2.2379664197970053, "Serum ferritin increased": 12.76199881401562, "Shock": 2.314983719551967, "Stevens-Johnson syndrome": 2.059709091711614, "Therapeutic response decreased": 5.085444742010496, "Therapy non-responder": 4.787486157925463, "Throat tightness": 5.015735851215882, "Unresponsive to stimuli": 36.18778342355522}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/735.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/735.json
index aaec224a869..8d588a01753 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/735.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/735.json
@@ -1 +1 @@
-{"Hypersensitivity ": 63.82604062080042, "Rash pruritic ": 198.8078758391397, "Urticaria ": 52.12986064766994}
\ No newline at end of file
+{"Application site erythema": 73.88376577264752, "Application site pain": 11.537680285135067, "Condition aggravated": 10.170270220550512, "Dermatitis": 22.3968792766074, "Dermatitis contact": 68.41485373281414, "Erythema": 27.25359351298729, "Feeling hot": 9.760374108496348, "Flushing": 31.52152054501875, "Hypersensitivity": 3.3112914639899858, "Rebound effect": 236.9391005386156, "Rosacea": 711.5949721018367, "Skin burning sensation": 105.16860408228771}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/736.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/736.json
index a1b6c994b6d..4865dcb07e5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/736.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/736.json
@@ -1 +1 @@
-{"Cardio-respiratory arrest ": 155.41552010783303, "Completed suicide ": 25.99729175529041, "Death ": 13.24132229025374, "Drug abuse ": 72.59094091393193, "Toxicity to various agents ": 31.393186735098087}
\ No newline at end of file
+{"Abdominal discomfort": 3.078737307373143, "Abdominal pain upper": 2.303762379264908, "Abortion induced incomplete": 376.5301586356688, "Alopecia": 2.832206746671133, "Aphasia": 20.77022373158293, "Atrial thrombosis": 220.9642656207368, "Blister": 5.008849940659971, "Dyskinesia": 21.520422080572413, "Exposure during pregnancy": 3.7550259546928393, "Inappropriate schedule of product administration": 7.772847748160262, "Induced abortion failed": 44.36925233704665, "Maternal exposure during pregnancy": 9.446188138221132, "Metabolic acidosis": 12.174774813714428, "Muscular weakness": 6.466238838833422, "Off label use": 2.791164498590329, "Paraesthesia oral": 19.61731223106112, "Postpartum haemorrhage": 274.6963063577937, "Product use in unapproved indication": 2.333179381335308, "Pulmonary thrombosis": 50.67295901262548, "Small for dates baby": 279.07197100062405, "Surgery": 40.02432412518667, "Thrombosis": 6.276124838980427, "Uterine rupture": 1028.3502611416975, "Vaginal haemorrhage": 25.645141802749496}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/737.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/737.json
index 1f3b7ca54f0..3f2c190689f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/737.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/737.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.376389242629678, "Bacterial endophthalmitis ": 3913.820333543581, "Constipation ": 3.786498101750929, "Disease progression ": 2.786520313663726, "Endophthalmitis ": 48.67939417933724, "Hypertension ": 2.232886592294536, "Intestinal obstruction ": 13.719040317628911, "Macular oedema ": 49.39423957211921, "Neuropathy peripheral ": 16.317162304897654, "Neutropenia ": 3.5918846442892827, "Off label use ": 5.058571844123431, "Ovarian cancer ": 41.772609923864295, "Pulmonary embolism ": 2.0226646515951123, "Rectal haemorrhage ": 4.942017048857083, "Thrombocytopenia ": 4.148706130123995}
\ No newline at end of file
+{"Adrenal insufficiency": 143.74734735871854, "Central hypothyroidism": 1979.9628794670311, "Disease progression": 7.289522860348299, "Hypothyroidism": 12.78136320557146, "Malignant neoplasm progression": 16.095815953969478, "Mineralocorticoid deficiency": 28927.234211841896, "Off label use": 14.430101426764928, "Product use in unapproved indication": 5.657312224280502}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/738.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/738.json
index a061a287848..f00cfa6d869 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/738.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/738.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 3.32319548744242, "Aspartate aminotransferase increased ": 3.064833133077701, "Blood bilirubin increased ": 7.456684090815462, "Candida infection ": 30.64944417198894, "Death ": 9.519610973294547, "Drug ineffective ": 2.665997422666876, "Fungal infection ": 12.813244983492597, "Haemolysis ": 38.06759928559801, "Haemolytic anaemia ": 18.52614058850419, "Hepatic cytolysis ": 10.635830280939317, "Hepatic enzyme increased ": 7.11490876436069, "Hepatic function abnormal ": 3.0241408115384925, "Intentional product misuse ": 3.040676915460081, "Jaundice ": 4.9417342443794565, "Multiple organ dysfunction syndrome ": 10.737063867899556, "Off label use ": 7.974546209364599, "Product use in unapproved indication ": 4.381018401171088, "Renal impairment ": 2.3924625668015924, "Respiratory failure ": 3.365906387549908, "Sepsis ": 6.16067849475906, "Thrombocytopenia ": 4.786201285534131, "Transaminases increased ": 9.10346476073404}
\ No newline at end of file
+{"Abortion spontaneous": 4.915194563394945, "Anaphylactic shock": 2.9126298870710503, "Angina pectoris": 3.6450654210813416, "Blood glucose abnormal": 21.036016878035117, "Blood glucose decreased": 7.097214063538854, "Blood glucose fluctuation": 19.7366608186142, "Blood glucose increased": 21.191317283004476, "Coma": 3.123999946806339, "Device failure": 29.74375471385549, "Diabetes mellitus inadequate control": 24.90666304953643, "Diabetic coma": 46.458681894083526, "Diabetic foot": 85.83869103505633, "Diabetic ketoacidosis": 27.385474127679416, "Gangrene": 31.619309296179427, "Glycosylated haemoglobin increased": 6.568116180033895, "Hyperglycaemia": 57.06103805491388, "Hypersensitivity": 4.453007068751582, "Hypoglycaemia": 34.552746984138324, "Hypoglycaemic coma": 117.8720885637614, "Injection site abscess": 68.76364098067428, "Injection site reaction": 5.044178056233551, "Liquid product physical issue": 46.19583586412519, "Maternal exposure during pregnancy": 3.0016215913852964, "Overdose": 2.180112163946692, "Pallor": 3.9617418968492, "Product quality issue": 7.925849101663631, "Product storage error": 8.659812233775915, "Treatment noncompliance": 5.101551800741766, "Wrong technique in product usage process": 4.966540947246091}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/739.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/739.json
index 128cbcc5612..f9e647ea26d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/739.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/739.json
@@ -1 +1 @@
-{"Abscess ": 3.259838442479331, "Actinic keratosis ": 29.976872359533868, "Acute graft versus host disease ": 18.17143152520908, "Acute graft versus host disease in intestine ": 29.80960152005947, "Acute graft versus host disease in liver ": 58.69114474023494, "Acute graft versus host disease in skin ": 35.37857387935901, "Acute respiratory distress syndrome ": 2.926447753267604, "Adenocarcinoma ": 14.050966833140434, "Adenovirus infection ": 19.08039826910249, "Adjustment disorder with depressed mood ": 5.500815660546509, "Anti-erythropoietin antibody negative ": 62.32364709530312, "Aplasia pure red cell ": 9.399504414378557, "Aspergillus infection ": 22.9935490410116, "Atrial septal defect ": 2.9144085509852693, "Autoimmune disorder ": 4.464571586242477, "BK virus infection ": 64.16217618913932, "Bacteraemia ": 10.709392825571816, "Bacterial infection ": 4.753356925718961, "Bacterial sepsis ": 14.400579843309377, "Basal cell carcinoma ": 3.82562973979104, "Blood creatinine increased ": 3.06481573361942, "Blood pressure diastolic abnormal ": 16.133871072828164, "Bowen's disease ": 64.15577438979065, "Brain abscess ": 16.074020065500108, "Bronchopulmonary aspergillosis ": 26.929603193258327, "C-reactive protein ": 7.7084372572895585, "C-reactive protein abnormal ": 3.4257231173121463, "COVID-19 pneumonia ": 4.37840932876692, "Choroiditis ": 207.8826678735093, "Chronic allograft nephropathy ": 80.89388865194267, "Chronic graft versus host disease ": 25.5321948162184, "Chronic graft versus host disease in skin ": 30.61991320903457, "Clostridium difficile colitis ": 2.867416718776701, "Clostridium difficile infection ": 2.2562725367629133, "Complications of transplanted kidney ": 96.10346077841476, "Condition aggravated ": 2.071515572707461, "Congenital anomaly in offspring ": 118.30553058830397, "Cryptococcosis ": 49.16147166318974, "Cushingoid ": 9.505314501869144, "Cystitis haemorrhagic ": 9.580642855830051, "Cytomegalovirus chorioretinitis ": 10.453757484435751, "Cytomegalovirus colitis ": 49.00925824957943, "Cytomegalovirus infection ": 49.11547792337547, "Cytomegalovirus infection reactivation ": 45.46914466321498, "Cytomegalovirus oesophagitis ": 97.57945056011022, "Cytomegalovirus test positive ": 13.55302129206948, "Cytomegalovirus viraemia ": 67.58303911517848, "Deep vein thrombosis postoperative ": 13.623505003549036, "Delayed graft function ": 213.09868682027556, "Diffuse large B-cell lymphoma ": 6.305544363025444, "Disseminated tuberculosis ": 16.672248245333595, "Drug interaction ": 2.4756588071148644, "Drug level increased ": 3.01768961820426, "Drug resistance ": 3.0396911705658147, "Duodenal ulcer perforation ": 3.714255700967463, "Encephalitis ": 3.838708246930884, "Endophthalmitis ": 8.316813263237535, "Enterococcal infection ": 18.384731467801107, "Epstein-Barr virus infection ": 26.37805706020179, "Epstein-Barr virus infection reactivation ": 19.043328315297224, "Escherichia infection ": 19.504960946915293, "Febrile neutropenia ": 2.587618501224336, "Fibromyalgia ": 2.1538809714135656, "Foetal growth restriction ": 4.008145349538796, "Folliculitis ": 2.090261069093498, "Fungal infection ": 8.881537006431833, "Gingival hypertrophy ": 11.531704646710814, "Graft versus host disease ": 15.416641353226195, "Graft versus host disease in gastrointestinal tract ": 33.62392949366133, "Graft versus host disease in skin ": 35.86845437186013, "Haemolytic anaemia ": 2.3839014661997275, "Haemophagocytic lymphohistiocytosis ": 7.553402835945369, "Heart transplant rejection ": 378.3491857867693, "Helicobacter infection ": 2.1221157607758925, "Hepatitis C ": 4.713906280729081, "Hepatitis E ": 46.77960080420841, "Histoplasmosis disseminated ": 100.02330172977037, "Human herpesvirus 6 infection ": 36.96272924040714, "Hydronephrosis ": 4.2588562025797145, "Hypercholesterolaemia ": 2.7622384369120505, "Hypogammaglobulinaemia ": 7.769776719502889, "Immune reconstitution inflammatory syndrome ": 2.537333217450452, "Immunosuppressant drug level decreased ": 26.11632803558124, "Immunosuppressant drug level increased ": 43.54833528534023, "Immunosuppression ": 6.88959264136623, "Impaired healing ": 2.2702477276897004, "Infection ": 2.3863514447589824, "Infection reactivation ": 50.180485758671146, "Intraocular pressure increased ": 6.39314413551151, "Kaposi's sarcoma ": 29.32600102404875, "Kidney fibrosis ": 27.65951176374417, "Kidney transplant rejection ": 70.929800746366, "Klebsiella infection ": 33.60958885421392, "Leukopenia ": 4.675234305738132, "Liver transplant rejection ": 37.03336670706999, "Localised infection ": 3.712961503535044, "Low birth weight baby ": 2.8153908894174893, "Lung infiltration ": 4.099191160928856, "Lung transplant rejection ": 50.09454433237544, "Lymphopenia ": 4.9875458444564815, "Malignant melanoma ": 2.360610977139317, "Mucormycosis ": 37.814590684748616, "Multiple organ dysfunction syndrome ": 4.072562385233291, "Mycobacterium avium complex infection ": 13.936788747017497, "Mycobacterium chelonae infection ": 40.13034780871492, "Mycobacterium haemophilum infection ": 295.84022379430326, "Myopathy ": 5.382053437002213, "Necrotising fasciitis ": 14.529584344702911, "Nephrectomy ": 16.403682988713747, "Nephropathy toxic ": 6.677698022101296, "Nephrotic syndrome ": 7.424659521508784, "Neutropenia ": 2.6755121806952684, "Nocardiosis ": 70.4218378211067, "Off label use ": 2.8294566652528577, "Opportunistic infection ": 31.335685602671106, "Osteomyelitis ": 2.723360144273229, "Pancytopenia ": 3.3596866918737027, "Papule ": 3.662419762310765, "Parvovirus B19 infection ": 83.11189606042485, "Peritonitis ": 3.214422121006701, "Pneumocystis jirovecii pneumonia ": 13.072287889091877, "Pneumonia ": 2.2162808758006376, "Pneumonia bacterial ": 6.415445726270518, "Pneumonia cytomegaloviral ": 45.275112236602936, "Polyomavirus viraemia ": 50.36090592134553, "Polyomavirus-associated nephropathy ": 175.33610809555947, "Post transplant lymphoproliferative disorder ": 67.84965207266681, "Posterior reversible encephalopathy syndrome ": 5.638336859025644, "Premature baby ": 2.3976253249398645, "Product use in unapproved indication ": 3.8993595125328055, "Progressive multifocal leukoencephalopathy ": 7.6479679881112705, "Proteinuria ": 5.134486465657435, "Pseudomonas infection ": 23.508561960276364, "Pulmonary mass ": 3.2598455729153497, "Pulmonary mucormycosis ": 94.65333735805204, "Pulmonary tuberculosis ": 9.78638286146358, "Pyelonephritis ": 3.543776549256607, "Rales ": 3.842133121245576, "Renal impairment ": 3.0646947639008943, "Renal transplant failure ": 134.16107115004408, "Renal tubular atrophy ": 30.744578105931502, "Renal tubular necrosis ": 7.743604056053625, "Respiratory failure ": 2.507956722803508, "Scleroderma ": 11.16677317624642, "Sepsis ": 4.117192490163676, "Septic shock ": 7.377238464992605, "Skin infection ": 6.338628070887749, "Skin lesion ": 3.4356428215250565, "Skin mass ": 7.927424619355481, "Skin plaque ": 5.740953783497286, "Smooth muscle cell neoplasm ": 116.2992879854938, "Splenomegaly ": 2.2510055548893777, "Squamous cell carcinoma ": 5.615078138353351, "Squamous cell carcinoma of skin ": 32.02257602776981, "Staphylococcal bacteraemia ": 9.481240695555716, "Staphylococcal infection ": 5.953067724101575, "Strongyloidiasis ": 65.07194970070154, "Therapy non-responder ": 4.002827639848039, "Thrombotic microangiopathy ": 11.557000540945156, "Transplant dysfunction ": 21.831008426222034, "Transplant failure ": 28.338988784353685, "Transplant rejection ": 82.47219106475374, "Tuberculosis ": 4.083420163765368, "Tubulointerstitial nephritis ": 2.039295664317062, "Urinary tract infection ": 2.230571036014113, "Urosepsis ": 3.926918980393963, "Uveitis ": 5.969201817680083, "Varicella zoster virus infection ": 24.95384070104273, "Venoocclusive liver disease ": 6.544657757662441, "Viral haemorrhagic cystitis ": 86.586966690326, "Visual acuity reduced ": 3.874615816425727, "Wound infection ": 7.200708827071009}
\ No newline at end of file
+{"Abnormal faeces": 2.2191072859617997, "Acute disseminated encephalomyelitis": 4.90569215227574, "Administration site erythema": 3.4670877470531285, "Allergy to metals": 126.83694354529229, "Antibody test negative": 20.75810856637325, "Apathy": 2.9328853250945754, "Aphthous ulcer": 2.1865439005874423, "Apnoea": 4.161526218099412, "Application site urticaria": 8.755671041850686, "Ataxia": 2.0973131117675377, "Autism spectrum disorder": 7.920540263553834, "Body temperature decreased": 6.548659433986612, "Body temperature increased": 3.589282046461688, "Breath holding": 51.02515718285372, "Catarrh": 18.710368379659894, "Conjunctival hyperaemia": 2.807183475292194, "Conjunctivitis": 18.754667283918312, "Cough": 3.600078545212548, "Crying": 49.1845845369857, "Cyanosis": 3.8544488244521657, "Cyanosis central": 24.479392325066605, "Decreased appetite": 3.1802960251244063, "Delirium febrile": 29.912972887841025, "Dermatitis atopic": 4.177515936600098, "Drooling": 6.935784455908836, "Ear 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19.86285678898617, "Vaccination site oedema": 6.734524941574374, "Vaccination site pruritus": 6.016484327402222, "Vaccination site rash": 6.036000036173157, "Vaccination site reaction": 4.148559475933312, "Vaccination site scar": 34.217966005721514, "Vaccination site swelling": 5.4202125544230855, "Vaccination site urticaria": 3.3470804440743254, "Vaccination site vesicles": 87.9787336902428, "Viral infection": 2.170415844695514, "Vomiting": 2.333339949878987, "Vomiting projectile": 3.1169022698731026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/74.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/74.json
index edf9eed75ac..ae8c080a98d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/74.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/74.json
@@ -1 +1 @@
-{"Completed suicide ": 62.16154448832651}
\ No newline at end of file
+{"Abscess": 3.369521401115291, "Adrenal insufficiency": 10.04349169260012, "Alpha tumour necrosis factor increased": 893.1091123770897, "Alveolar proteinosis": 133.8890029182049, "Ankle arthroplasty": 113.78756154357916, "Ankylosing spondylitis": 2.234909888724937, "Anti-cyclic citrullinated peptide antibody positive": 5.207078936543889, "Anti-neutrophil cytoplasmic antibody positive vasculitis": 10.215690169036352, "Antibody test positive": 50.79758454212926, "Apparent death": 691.0562639530008, "Arthritis": 3.010158760308475, "Arthrodesis": 211.63000129851383, "Arthropathy": 12.857519718516471, "Aspartate aminotransferase": 99.00280369832056, "Autoinflammatory disease": 235.28520281894848, "Axial spondyloarthritis": 171.9747593651108, "Back disorder": 2.0396014735908925, "Barotrauma": 639.6686229968712, "Basal cell carcinoma": 3.026427551380453, "Blister rupture": 32.153824054436335, "Blood glucose fluctuation": 2.094585372212004, "Blood immunoglobulin A increased": 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2.6264943046005205, "Contraindicated product administered": 21.41225754198536, "Coordination abnormal": 2.3654530133217557, "Cytokine release syndrome": 4.416757915303097, "Deep vein thrombosis": 7.391566688741732, "Deformity": 93.80159978405264, "Diverticulitis": 30.45770148026149, "Drug hypersensitivity": 11.136177556768857, "Drug ineffective": 5.217358185309077, "Drug intolerance": 10.474060525146315, "Drug specific antibody": 41.446128233003, "Drug specific antibody present": 33.1910186422276, "Drug use disorder": 4.411145635859244, "Endodontic procedure": 55.83682576514275, "Febrile infection-related epilepsy syndrome": 506.1734940613872, "Feeling abnormal": 2.190436924521276, "Fine motor skill dysfunction": 8.65036164497117, "Finger deformity": 5.790085745544645, "Foot deformity": 15.941327594748644, "Foot operation": 16.659282535172903, "Gastroenteritis viral": 2.880424077499184, "Gastrointestinal perforation": 12.88716872677673, "Glucose tolerance impaired": 21.94305978070569, "Grip strength decreased": 4.377738667125497, "Haemodynamic instability": 3.116900988685394, "Haemoglobin decreased": 2.9179190553092926, "Haemophagocytic lymphohistiocytosis": 17.3576464737494, "Hair follicle tumour benign": 237.1010437372663, "Hand deformity": 6.200412063138442, "Heart rate decreased": 2.187898082799443, "Hepatosplenic T-cell lymphoma": 128.46614996832704, "Hepatosplenomegaly": 6.028287199199661, "Hepatotoxicity": 21.25768806349301, "Herpes zoster": 2.8534408136349603, "Human antichimeric antibody positive": 323.69531670912704, "Hyperlipidaemia": 2.067139968870847, "Hyperparathyroidism secondary": 59.29359095841062, "Hypomagnesaemia": 6.408703977881552, "Ill-defined disorder": 20.493755369896384, "Impaired healing": 2.674021417213229, "Impaired quality of life": 12.896909009287018, "Impaired work ability": 4.581584463408498, "Infection": 3.4848621381477685, "Infection susceptibility increased": 6.018386933901725, "Inhibitory drug interaction": 10.400095301422152, 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abnormal": 160.41481570885662, "Red blood cell sedimentation rate decreased": 72.47265481154687, "Red blood cell sedimentation rate increased": 56.95258659095852, "Renal failure": 2.569817142175611, "Rheumatoid arthritis": 14.801589004658808, "Rheumatoid factor positive": 19.17093532128361, "Sacroiliitis": 41.32133760869912, "Sciatica": 2.4237926097515583, "Sepsis": 4.668222831495115, "Septic shock": 3.457157713267575, "Serum ferritin increased": 9.638291205108745, "Shoulder arthroplasty": 113.90256328444424, "Skin fissures": 8.313411555064963, "Smear cervix abnormal": 71.26830444200453, "Spinal stenosis": 2.704752446824384, "Splenomegaly": 4.068857046522883, "Spondyloarthropathy": 114.69203175630896, "Stent placement": 13.3853097038767, "Still's disease": 38.1235868330441, "Stomatitis": 3.188435502399234, "Syncope": 2.273249956759648, "Synovial cyst": 8.51183343765308, "Synovitis": 13.7823836863213, "T-cell lymphoma": 28.568087594253928, "Terminal state": 75.131317669066, "Therapeutic product effect decreased": 16.05353190394737, "Therapeutic product effect incomplete": 10.098439308614196, "Therapy non-responder": 3.132154404317054, "Thrombosis": 4.026726520763146, "Tooth disorder": 4.621005184961777, "Toothache": 3.75166986511141, "Treatment failure": 12.594683094747708, "Type IV hypersensitivity reaction": 14.761457461393348, "Ulcer": 5.779120324456717, "Vitamin D decreased": 16.937498624834127, "Wheelchair user": 7.070819348723306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/740.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/740.json
index 18586884414..4b5362320eb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/740.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/740.json
@@ -1 +1 @@
-{"Death ": 20.988130933449742}
\ No newline at end of file
+{"Administration site erythema": 2.869194137840116, "Administration site swelling": 23.25520607601861, "Adnexa uteri pain": 10.18539310419225, "Amenorrhoea": 5.74424857538131, "Axillary mass": 2.0692154251853023, "Axillary pain": 5.923419121732695, "Breast pain": 3.6338927728874273, "COVID-19 immunisation": 11.405679586884942, "COVID-19 pneumonia": 3.190515885320516, "Catarrh": 2.745513515077157, "Cervicobrachial syndrome": 9.523450420830487, "Chillblains": 6.294648697721823, "Deafness unilateral": 2.5264058805001435, "Dizziness postural": 2.4012530381011645, "Dysmenorrhoea": 6.480535167294683, "Endometriosis": 3.361286785043206, "Erythema nodosum": 2.103756079704656, "Facial paralysis": 2.4609955054033974, "Formication": 4.293332193948601, "Headache": 2.2758392761120385, "Heavy menstrual bleeding": 4.4604050797082975, "Hemiparaesthesia": 4.068588214841811, "Immunisation reaction": 27.996419448719347, "Increased viscosity of upper respiratory secretion": 12.575984174921205, "Influenza like illness": 5.07894610531853, "Injected limb mobility decreased": 2.4147188638591595, "Injection site erythema": 3.562947684198091, "Injection site joint erythema": 34.2853694186257, "Injection site joint swelling": 78.01761768383675, "Injection site oedema": 3.20219690623795, "Injection site paraesthesia": 6.336862328560651, "Injection site rash": 5.540979609357985, "Injection site urticaria": 4.789688056225117, "Intermenstrual bleeding": 5.066267212628726, "Local reaction": 2.012589058948204, "Lymphadenitis": 5.819029557824164, "Lymphadenopathy": 5.61049618001774, "Malaise": 3.5295753164236947, "Mastitis": 2.5129546396498954, "Mechanical urticaria": 6.741333063009982, "Menometrorrhagia": 16.838608953042066, "Menstrual disorder": 3.855262478818579, "Menstruation delayed": 4.02462284743569, "Menstruation irregular": 4.90167861289466, "Muscle contractions involuntary": 2.694911661188221, "Myalgia": 3.060643776360176, "Myocarditis": 2.2646730302435576, "Myopericarditis": 5.691354817371805, "Neuralgic amyotrophy": 5.295745608554054, "Nuchal rigidity": 4.97499408177851, "Odynophagia": 8.676878750232142, "Oligomenorrhoea": 7.137204516220444, "Oral herpes": 2.801354546156851, "Paraesthesia": 2.274504805122576, "Pelvic pain": 4.219909553365011, "Periarthritis": 2.688440220452068, "Pericarditis": 2.076286857995606, "Polymenorrhoea": 4.689739456924431, "Polymyalgia rheumatica": 2.793531682255277, "Premenstrual pain": 3.7570987821666, "Premenstrual syndrome": 13.002946199411834, "Pyrexia": 5.228916100004721, "Skin reaction": 3.3949171632973134, "Superficial vein thrombosis": 2.3429111653225085, "Temperature regulation disorder": 19.86856228141124, "Tinnitus": 3.143353513750849, "Urticaria chronic": 2.4439496973921404, "Uterine haemorrhage": 5.110606431904274, "Uterine pain": 7.186007053708341, "Vaccination site cellulitis": 12.33439933654798, "Vaccination site discomfort": 4.526527069205722, "Vaccination site eczema": 16.21391064668421, "Vaccination site erythema": 4.8991115299175645, "Vaccination site haematoma": 12.779116524115253, "Vaccination site induration": 14.449464873076607, "Vaccination site inflammation": 105.10557487413904, "Vaccination site joint erythema": 48.33606911024823, "Vaccination site joint pain": 6.832184473845358, "Vaccination site lymphadenopathy": 37.69888942720888, "Vaccination site mass": 10.830665678169686, "Vaccination site movement impairment": 7.109649302215687, "Vaccination site oedema": 12.561405836200535, "Vaccination site pain": 8.839697699495801, "Vaccination site paraesthesia": 13.653520435062642, "Vaccination site pruritus": 8.54038701845057, "Vaccination site rash": 27.52946239533655, "Vaccination site reaction": 12.233662358853032, "Vaccination site swelling": 2.7676956969680897, "Vaccination site urticaria": 16.703885216285972, "Vaccination site warmth": 7.892420125927168, "Vertigo": 2.1247053925457484, "Vestibular neuronitis": 2.743255666796249}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/741.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/741.json
index a7a7460f7f3..9602ee4b187 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/741.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/741.json
@@ -1 +1 @@
-{"Neutropenia ": 17.874909035868072, "Thrombocytopenia ": 11.619604536662752}
\ No newline at end of file
+{"Blood glucose increased": 7.70676283649294, "Constipation": 5.630627601128025, "Decreased appetite": 3.3489421289254646, "Hypoglycaemia": 10.87149494834562, "Pancreatitis": 12.105980806309844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/742.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/742.json
index 1c59f18d4bf..edee0ea342f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/742.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/742.json
@@ -1 +1 @@
-{"Acute respiratory failure ": 5.054972475146406, "Adenoidectomy ": 117.32806557153818, "Aortic valve incompetence ": 21.161389535196328, "Apnoea ": 8.688030289211124, "Atelectasis ": 3.986047322358089, "Bacteraemia ": 4.12489650054704, "Blindness ": 2.930696847597626, "Body temperature increased ": 5.537805575717448, "Bone marrow transplant ": 51.802174574825216, "Brain oedema ": 2.815338211238017, "Bronchitis ": 2.2190030684039117, "Bronchospasm ": 7.0777177538668345, "Cardiac arrest ": 3.0666939014187347, "Cardiac disorder ": 2.6926295172548267, "Cardiac failure ": 2.5466420777667587, "Cardiac valve disease ": 26.053764349524972, "Cardio-respiratory arrest ": 4.474758849921239, "Cardiomegaly ": 2.968025056718841, "Carpal tunnel syndrome ": 14.148462967139364, "Catheter site bruise ": 596.0261588194577, "Catheter site erythema ": 32.256401947237606, "Catheter site pain ": 63.43451235684668, "Catheter site swelling ": 60.489012398999606, "Cervical cord compression ": 1075.072725692061, "Cervical spinal stenosis ": 141.75257451018143, "Conductive deafness ": 102.7254168767744, "Corneal opacity ": 123.44992596131256, "Cough ": 5.784291780117073, "Cyanosis ": 14.11580667249142, "Device related infection ": 28.215620515878587, "Dyspnoea ": 2.187795528396308, "Ear infection ": 16.14292577081708, "Ear pain ": 6.819212420057196, "Ear tube insertion ": 224.98271827603617, "Endotracheal intubation complication ": 85.13119231268217, "Extravasation ": 11.603848051508804, "Febrile infection ": 134.86324540865525, "Gastrointestinal infection ": 22.614233901482383, "Glaucoma ": 2.1359201923771782, "Head injury ": 4.805716466873002, "Heart rate increased ": 2.526161159656514, "Hernia ": 8.039563023613974, "Hip surgery ": 18.805963814719306, "Hydrocephalus ": 48.25251103409794, "Hyperreflexia ": 9.1409000221061, "Hypokinesia ": 2.110000820419972, "Hypotonia ": 2.275604655989829, "Infection ": 2.4980511055612875, "Infusion related reaction ": 8.652112624932109, "Infusion site extravasation ": 25.48472702528333, "Infusion site swelling ": 29.761105911720964, "Inguinal hernia ": 19.263277958292253, "Intracranial pressure increased ": 21.1625453452651, "Intraocular pressure increased ": 3.856241412791796, "Knee operation ": 9.440127909780838, "Kyphosis ": 47.95198316963607, "Livedo reticularis ": 10.280916975096504, "Lung disorder ": 2.11455468526692, "Mitral valve incompetence ": 18.558064266761303, "Muscle spasticity ": 4.511658172215146, "Myelopathy ": 35.243267916551126, "Nasal congestion ": 4.184875841004458, "Nasopharyngitis ": 7.123502353363376, "Obstructive airways disorder ": 5.273498934977887, "Obstructive sleep apnoea syndrome ": 15.092124930041056, "Oropharyngeal pain ": 4.090064569810644, "Oxygen saturation decreased ": 12.78571142085263, "Pallor ": 7.545442536452517, "Pharyngitis ": 4.014109436519468, "Pneumonia ": 8.085622593983768, "Poor venous access ": 155.0225596220758, "Product administration error ": 3.5445046443729047, "Product dose omission issue ": 3.9549973367836473, "Productive cough ": 5.686594710825485, "Pulmonary hypertension ": 12.240760215941242, "Pulmonary oedema ": 2.429946561172671, "Quadriplegia ": 23.55633315203572, "Respiratory arrest ": 3.7352027350288832, "Respiratory disorder ": 10.744914177809369, "Respiratory distress ": 6.489544160524841, "Respiratory failure ": 6.040385589391623, "Respiratory rate increased ": 5.705635668774408, "Respiratory tract infection ": 6.334084435864783, "Rhinorrhoea ": 8.644132215498562, "Scoliosis ": 7.538732418272471, "Secretion discharge ": 15.197310440512474, "Seizure ": 2.4327101910483493, "Skin abrasion ": 7.639355211964621, "Sleep apnoea syndrome ": 9.126215317740336, "Spinal cord compression ": 414.2270756115629, "Spinal decompression ": 380.2819896299943, "Spinal disorder ": 8.843543160869503, "Spinal operation ": 12.341751546978166, "Spinal pain ": 3.490641462680023, "Spinal stenosis ": 8.016393608331835, "Tachycardia ": 2.394002931237657, "Tachypnoea ": 8.241698594404456, "Tonsillectomy ": 53.80221331505649, "Tracheomalacia ": 95.33772042909148, "Tracheostomy ": 78.00385813281233, "Tracheostomy malfunction ": 269.09333044475574, "Tricuspid valve incompetence ": 6.41854196340814, "Umbilical hernia ": 23.40009916876121, "Upper respiratory tract infection ": 3.5069433582323035, "Urinary tract infection ": 2.7146709970404883, "Vascular access complication ": 102.4493073928636, "Viral infection ": 5.774838559797415}
\ No newline at end of file
+{"Abdominal distension": 2.8812252249388832, "Abdominal pain upper": 2.458505551882922, "Accidental overdose": 10.739194637913451, "Accidental underdose": 331.37723142486703, "Asthenia": 2.0221913254041795, "Back pain": 4.878319875407518, "Blood pressure increased": 2.014162565834745, "Bone pain": 4.431744975003668, "Condition aggravated": 2.057962821253692, "Dizziness": 3.0104752616200763, "Dyspepsia": 3.8862109221233063, "Hypercalcaemia": 21.41948279786065, "Injection site erythema": 7.8839659616020095, "Injection site haematoma": 26.99942879771171, "Muscle spasms": 5.74445811752924, "Nausea": 2.0920421286507853, "Pain in extremity": 3.482309852519288, "Palpitations": 2.849534765575867, "Peripheral swelling": 2.0284355272018013, "Poor quality product administered": 46.00860432469364, "Product dose omission issue": 2.2077498776996367, "Tachycardia": 3.384523321679404, "Urinary incontinence": 9.093557188303851, "Vertigo": 4.008758195843696, "Weight increased": 2.946213359181612, "Wrong technique in device usage process": 169.257777761374}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/743.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/743.json
index a374114c4c9..2859c82a6da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/743.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/743.json
@@ -1 +1 @@
-{"Drug interaction ": 34.28667812504846, "Drug withdrawal syndrome ": 80.94441726232563, "Vomiting ": 3.784264609626409, "Withdrawal syndrome ": 86.23155975683488}
\ No newline at end of file
+{"Acute hepatic failure": 5.140314491514364, "Acute pulmonary oedema": 4.294321954024987, "Alanine aminotransferase increased": 7.750640114159855, "Arrhythmia": 5.199257544728525, "Aspartate aminotransferase increased": 7.897331596603005, "Atrial fibrillation": 42.74818343557723, "Atrial flutter": 27.74035632452737, "Blood alkaline phosphatase increased": 7.366273034055711, "Blood bilirubin increased": 6.128848835164764, "Blood creatinine increased": 10.203298766751136, "Blood potassium increased": 2.5343356117869105, "Blood thyroid stimulating hormone increased": 4.8979461643180615, "Blood urea increased": 3.67620570405038, "Bradycardia": 5.644337114995368, "Brain natriuretic peptide increased": 17.529504878493565, "Cardiac arrest": 2.258779567346792, "Cardiac failure": 10.698518105136452, "Cardiac failure chronic": 10.43157828006213, "Cardiac failure congestive": 8.482886927823872, "Cardiac flutter": 3.7966228865027967, "Cholestatic liver injury": 21.13172429581888, "Chromaturia": 3.3400013365444763, "Coagulopathy": 2.6557711681417056, "Condition aggravated": 2.122456518787383, "Drug interaction": 3.369512456082493, "Drug-induced liver injury": 2.168670591190381, "Dyspnoea": 2.737664409502148, "Dyspnoea exertional": 3.020335282606203, "Ejection fraction decreased": 8.172417815673962, "Electrocardiogram QT prolonged": 9.647649004262677, "Electrocardiogram abnormal": 3.2559949144933698, "Emphysema": 4.678500418194788, "Extrasystoles": 6.433265702433401, "Fluid retention": 2.590595479182258, "Gamma-glutamyltransferase increased": 13.096070626026156, "Gastrointestinal disorder": 2.347404018016244, "Glomerular filtration rate decreased": 10.712231050801597, "Heart rate decreased": 10.769817329415172, "Heart rate increased": 3.281542336909132, "Heart rate irregular": 6.985750944358415, "Hepatic enzyme increased": 4.548486744941788, "Hepatic failure": 5.437816619526552, "Hepatitis": 3.08676594123693, "Hepatitis acute": 3.964794264298266, "Hepatitis toxic": 6.139875882219048, "Hepatocellular injury": 59.06876295073005, "Hepatotoxicity": 2.2396029478194133, "Hyperthyroidism": 6.798906501024758, "Hypertransaminasaemia": 2.3460573106831637, "International normalised ratio abnormal": 8.62087862811712, "International normalised ratio decreased": 4.887511920054617, "International normalised ratio increased": 14.238108353615944, "Interstitial lung disease": 2.251515553064867, "Jaundice": 3.908589244910284, "Left ventricular failure": 10.09203072065948, "Liver function test abnormal": 5.79210362936562, "Liver function test increased": 6.135229458683927, "Liver injury": 3.457507176451214, "Long QT syndrome": 11.484943071370012, "Lung disorder": 2.1862765197534446, "Lung infiltration": 5.005714737087952, "Mixed liver injury": 10.017366773863175, "Oedema": 3.054920461652236, "Oedema peripheral": 4.36494335860944, "Papilloedema": 4.683874972733009, "Pericardial effusion": 2.284978435869312, "Photosensitivity reaction": 6.33796335013457, "Pleural effusion": 2.12938179853425, "Polyneuropathy": 2.378831802044324, "Prothrombin time prolonged": 2.7897714157547737, "Pulmonary congestion": 3.612147838508995, "Pulmonary fibrosis": 8.012815510561927, "Pulmonary oedema": 3.857376190703645, "Pulmonary toxicity": 8.409473394434361, "Sinus bradycardia": 4.171222645077596, "Sudden cardiac death": 8.523491933733446, "Sudden death": 3.38538492458209, "Torsade de pointes": 13.64594892288073, "Transaminases increased": 10.02760317782628, "Underdose": 9.33628254728198, "Ventricular extrasystoles": 8.343785143255133, "Ventricular fibrillation": 7.301459660059155, "Ventricular tachycardia": 15.582914583588828, "Weight increased": 3.217711318469331, "Wrong technique in product usage process": 2.202025732545953}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/744.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/744.json
index da973c6ad65..933e29edd8c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/744.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/744.json
@@ -1 +1 @@
-{"Agitation ": 2.953017410227095, "Altered state of consciousness ": 4.9580686514756165, "Apnoea ": 69.22507979239305, "Aspartate aminotransferase increased ": 3.540408714146838, "Blood albumin decreased ": 64.424764673388, "Blood potassium decreased ": 14.426299324941953, "Bradypnoea ": 70.86399642644066, "Brain death ": 68.56268387164482, "Brain injury ": 28.36220972493608, "Brain oedema ": 27.452836616213578, "Cardiac arrest ": 8.769090004829028, "Coma ": 3.5808030444649783, "Completed suicide ": 2.1268667739415084, "Confusional state ": 4.6346838281898, "Depressed level of consciousness ": 14.175203049477204, "Drug abuse ": 5.4057542540033925, "Drug dependence ": 2.240456040552168, "Drug hypersensitivity ": 3.2856144298734145, "Drug interaction ": 4.5710313847020485, "Drug withdrawal syndrome ": 8.763207396830463, "Drug withdrawal syndrome neonatal ": 15.11581335382122, "Dysarthria ": 4.290598408555982, "Electrocardiogram QT prolonged ": 13.492775247763587, "Emotional distress ": 2.081520108533881, "Foetal exposure during pregnancy ": 3.5060697833212155, "Haematocrit decreased ": 15.3371753997248, "Haemoglobin decreased ": 3.37101379335646, "Heart rate increased ": 5.450495230275104, "Hypotension ": 3.087550894667707, "Hypoxia ": 6.211441553980293, "Intentional overdose ": 2.196628648644798, "Intentional product misuse ": 2.365366297291258, "Irritability ": 9.067195014530611, "Loss of consciousness ": 4.518094004215677, "Mental status changes ": 25.83439398790766, "Miosis ": 65.87776609155605, "Mydriasis ": 14.660874080202383, "Overdose ": 18.58924069369474, "Oxygen saturation decreased ": 12.215405345823244, "Pulmonary oedema ": 8.185749641004541, "Pupil fixed ": 95.07926110935236, "Respiratory alkalosis ": 399.3790692786419, "Respiratory arrest ": 14.68365083925587, "Respiratory depression ": 18.967529158242627, "Respiratory failure ": 3.3170739511150056, "Sedation ": 20.535025536120216, "Sinus tachycardia ": 37.17687997493727, "Somnolence ": 3.1612197135021844, "Suicide attempt ": 9.202474161478769, "Toxicity to various agents ": 14.069781061849614, "Unresponsive to stimuli ": 53.956637931813454}
\ No newline at end of file
+{"Hypersensitivity": 63.82604062080042, "Rash pruritic": 198.8078758391397, "Urticaria": 52.12932661667173}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/745.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/745.json
index 2bc0d645f54..ecd5d0436e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/745.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/745.json
@@ -1 +1 @@
-{"Completed suicide ": 39.61870617487866}
\ No newline at end of file
+{"Cardio-respiratory arrest": 155.41552010783303, "Completed suicide": 25.99729175529041, "Death": 13.24132229025374, "Drug abuse": 72.59094091393193, "Toxicity to various agents": 31.393186735098087}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/746.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/746.json
index f9824e76f50..083f3aa864b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/746.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/746.json
@@ -1 +1 @@
-{"Blood calcium decreased ": 160.57237064988138, "Drug ineffective ": 3.1211574668081687, "Hypocalcaemia ": 270.811839485896, "Paraesthesia ": 2.9420328543551912}
\ No newline at end of file
+{"Abdominal pain": 2.376389242629678, "Bacterial endophthalmitis": 3913.820333543581, "Constipation": 3.786498101750929, "Disease progression": 2.786520313663726, "Endophthalmitis": 48.67939417933724, "Hypertension": 2.232863540936824, "Intestinal obstruction": 13.719040317628911, "Macular oedema": 49.39423957211921, "Neuropathy peripheral": 16.316666463453135, "Neutropenia": 3.5917301746319508, "Off label use": 5.058372550899695, "Ovarian cancer": 41.772609923864295, "Pulmonary embolism": 2.0226646515951123, "Rectal haemorrhage": 4.942017048857083, "Thrombocytopenia": 4.148315808003399}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/747.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/747.json
index eecf45bd119..90c56328d75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/747.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/747.json
@@ -1 +1 @@
-{"Vitiligo ": 830.8278739549502}
\ No newline at end of file
+{"Alanine aminotransferase increased": 3.32319548744242, "Aspartate aminotransferase increased": 3.064833133077701, "Blood bilirubin increased": 7.456684090815462, "Candida infection": 30.64944417198894, "Death": 9.519610973294547, "Drug ineffective": 2.665977713139058, "Fungal infection": 12.80968933405287, "Haemolysis": 38.06759928559801, "Haemolytic anaemia": 18.52614058850419, "Hepatic cytolysis": 10.635830280939317, "Hepatic enzyme increased": 7.11490876436069, "Hepatic function abnormal": 3.0241408115384925, "Intentional product misuse": 3.040676915460081, "Jaundice": 4.9417342443794565, "Multiple organ dysfunction syndrome": 10.737063867899556, "Off label use": 7.974231979982068, "Product use in unapproved indication": 4.3808817636353945, "Renal impairment": 2.3924625668015924, "Respiratory failure": 3.365628513251994, "Sepsis": 6.16067849475906, "Thrombocytopenia": 4.785750975043946, "Transaminases increased": 9.102907153273328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/748.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/748.json
index a46663d9d70..1cce8acbf6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/748.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/748.json
@@ -1 +1 @@
-{"Anaemia ": 20.56457281044169, "Anti-erythropoietin antibody positive ": 816.2697011790758, "Aplasia pure red cell ": 473.508449493159, "Drug ineffective ": 4.217794212699562, "Drug specific antibody ": 367.845356566029, "Encephalopathy ": 17.58191376622502, "Haemoglobin decreased ": 12.01261877135546, "Pancytopenia ": 9.79841557335311, "Sudden death ": 33.9341003316681, "Therapeutic response decreased ": 49.68076132999248, "Thrombocytopenia ": 3.402614321255196}
\ No newline at end of file
+{"Abscess": 3.259838442479331, "Actinic keratosis": 29.976872359533868, "Acute graft versus host disease": 18.17143152520908, "Acute graft versus host disease in intestine": 29.80960152005947, "Acute graft versus host disease in liver": 58.69114474023494, "Acute graft versus host disease in skin": 35.37857387935901, "Acute respiratory distress syndrome": 2.926447753267604, "Adenocarcinoma": 14.050966833140434, "Adenovirus infection": 19.08039826910249, "Adjustment disorder with depressed mood": 5.500815660546509, "Anti-erythropoietin antibody negative": 62.32364709530312, "Aplasia pure red cell": 9.399504414378557, "Aspergillus infection": 22.9935490410116, "Atrial septal defect": 2.9144085509852693, "Autoimmune disorder": 4.464571586242477, "BK virus infection": 64.16217618913932, "Bacteraemia": 10.709392825571816, "Bacterial infection": 4.753356925718961, "Bacterial sepsis": 14.400579843309377, "Basal cell carcinoma": 3.82562973979104, "Blood creatinine increased": 3.06481573361942, "Blood pressure diastolic abnormal": 16.133871072828164, "Bowen's disease": 64.15577438979065, "Brain abscess": 16.074020065500108, "Bronchopulmonary aspergillosis": 26.929603193258327, "C-reactive protein": 7.7084372572895585, "C-reactive protein abnormal": 3.4257231173121463, "COVID-19 pneumonia": 4.37840932876692, "Choroiditis": 207.8826678735093, "Chronic allograft nephropathy": 80.89388865194267, "Chronic graft versus host disease": 25.5321948162184, "Chronic graft versus host disease in skin": 30.61991320903457, "Clostridium difficile colitis": 2.867416718776701, "Clostridium difficile infection": 2.2562725367629133, "Complications of transplanted kidney": 96.10346077841476, "Condition aggravated": 2.071515572707461, "Congenital anomaly in offspring": 118.30553058830397, "Cryptococcosis": 49.16147166318974, "Cushingoid": 9.505314501869144, "Cystitis haemorrhagic": 9.580642855830051, "Cytomegalovirus chorioretinitis": 10.453757484435751, "Cytomegalovirus colitis": 49.00925824957943, "Cytomegalovirus infection": 49.11547792337547, "Cytomegalovirus infection reactivation": 45.46914466321498, "Cytomegalovirus oesophagitis": 97.57945056011022, "Cytomegalovirus test positive": 13.55302129206948, "Cytomegalovirus viraemia": 67.58303911517848, "Deep vein thrombosis postoperative": 13.623505003549036, "Delayed graft function": 213.09868682027556, "Diffuse large B-cell lymphoma": 6.305544363025444, "Disseminated tuberculosis": 16.672248245333595, "Drug interaction": 2.4756588071148644, "Drug level increased": 3.01768961820426, "Drug resistance": 3.0396911705658147, "Duodenal ulcer perforation": 3.714255700967463, "Encephalitis": 3.838708246930884, "Endophthalmitis": 8.316813263237535, "Enterococcal infection": 18.384731467801107, "Epstein-Barr virus infection": 26.37805706020179, "Epstein-Barr virus infection reactivation": 19.043328315297224, "Escherichia infection": 19.504960946915293, "Febrile neutropenia": 2.587618501224336, "Fibromyalgia": 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"Immunosuppressant drug level increased": 43.54833528534023, "Immunosuppression": 6.88959264136623, "Impaired healing": 2.2702477276897004, "Infection": 2.3863514447589824, "Infection reactivation": 50.180485758671146, "Intraocular pressure increased": 6.39314413551151, "Kaposi's sarcoma": 29.32600102404875, "Kidney fibrosis": 27.65951176374417, "Kidney transplant rejection": 70.929800746366, "Klebsiella infection": 33.60958885421392, "Leukopenia": 4.674643474682354, "Liver transplant rejection": 37.03336670706999, "Localised infection": 3.712961503535044, "Low birth weight baby": 2.8153908894174893, "Lung infiltration": 4.099191160928856, "Lung transplant rejection": 50.09454433237544, "Lymphopenia": 4.9875458444564815, "Malignant melanoma": 2.360610977139317, "Mucormycosis": 37.814590684748616, "Multiple organ dysfunction syndrome": 4.072562385233291, "Mycobacterium avium complex infection": 13.936788747017497, "Mycobacterium chelonae infection": 40.13034780871492, "Mycobacterium haemophilum infection": 295.84022379430326, "Myopathy": 5.382053437002213, "Necrotising fasciitis": 14.529584344702911, "Nephrectomy": 16.403682988713747, "Nephropathy toxic": 6.677698022101296, "Nephrotic syndrome": 7.424659521508784, "Neutropenia": 2.675396964563021, "Nocardiosis": 70.4218378211067, "Off label use": 2.829345048132251, "Opportunistic infection": 31.335685602671106, "Osteomyelitis": 2.723360144273229, "Pancytopenia": 3.3596866918737027, "Papule": 3.662419762310765, "Parvovirus B19 infection": 83.11189606042485, "Peritonitis": 3.214422121006701, "Pneumocystis jirovecii pneumonia": 13.072287889091877, "Pneumonia": 2.2162808758006376, "Pneumonia bacterial": 6.415445726270518, "Pneumonia cytomegaloviral": 45.275112236602936, "Polyomavirus viraemia": 50.36090592134553, "Polyomavirus-associated nephropathy": 175.33610809555947, "Post transplant lymphoproliferative disorder": 67.84965207266681, "Posterior reversible encephalopathy syndrome": 5.638336859025644, "Premature baby": 2.3976253249398645, "Product use in unapproved indication": 3.899237649259889, "Progressive multifocal leukoencephalopathy": 7.6479679881112705, "Proteinuria": 5.134486465657435, "Pseudomonas infection": 23.508561960276364, "Pulmonary mass": 3.2598455729153497, "Pulmonary mucormycosis": 94.65333735805204, "Pulmonary tuberculosis": 9.78638286146358, "Pyelonephritis": 3.543776549256607, "Rales": 3.842133121245576, "Renal impairment": 3.0646947639008943, "Renal transplant failure": 134.16107115004408, "Renal tubular atrophy": 30.744578105931502, "Renal tubular necrosis": 7.743604056053625, "Respiratory failure": 2.507749399276135, "Scleroderma": 11.16677317624642, "Sepsis": 4.117192490163676, "Septic shock": 7.377238464992605, "Skin infection": 6.338628070887749, "Skin lesion": 3.4356428215250565, "Skin mass": 7.927424619355481, "Skin plaque": 5.740953783497286, "Smooth muscle cell neoplasm": 116.2992879854938, "Splenomegaly": 2.2510055548893777, "Squamous cell carcinoma": 5.615078138353351, "Squamous cell carcinoma of skin": 32.02257602776981, "Staphylococcal bacteraemia": 9.481240695555716, "Staphylococcal infection": 5.953067724101575, "Strongyloidiasis": 65.07194970070154, "Therapy non-responder": 4.002477248628407, "Thrombotic microangiopathy": 11.557000540945156, "Transplant dysfunction": 21.831008426222034, "Transplant failure": 28.338988784353685, "Transplant rejection": 82.47219106475374, "Tuberculosis": 4.083420163765368, "Tubulointerstitial nephritis": 2.039295664317062, "Urinary tract infection": 2.230571036014113, "Urosepsis": 3.926918980393963, "Uveitis": 5.969201817680083, "Varicella zoster virus infection": 24.95384070104273, "Venoocclusive liver disease": 6.544657757662441, "Viral haemorrhagic cystitis": 86.586966690326, "Visual acuity reduced": 3.874615816425727, "Wound infection": 7.200708827071009}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/749.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/749.json
index ec39174e5b6..22717d99176 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/749.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/749.json
@@ -1 +1 @@
-{"Corneal epithelium defect ": 3128.8831920553766, "Cystoid macular oedema ": 1901.787519708332, "Eye pain ": 23.506506338721024, "Foreign body sensation in eyes ": 629.2321277083585, "Ocular hyperaemia ": 52.03467092134263, "Ulcerative keratitis ": 642.186582802253, "Visual acuity reduced ": 76.68996211924863}
\ No newline at end of file
+{"Death": 20.988130933449742}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/75.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/75.json
index 9e26dfeeb6e..60459597534 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/75.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/75.json
@@ -1 +1 @@
-{}
\ No newline at end of file
+{"Completed suicide": 62.16154448832651}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/750.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/750.json
index 653362b817a..4e7149bc1f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/750.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/750.json
@@ -1 +1 @@
-{"Diarrhoea ": 2.33088420474321, "Hypotension ": 12.733666219569365, "Pruritus ": 5.702652579284429}
\ No newline at end of file
+{"Neutropenia": 17.874140421853756, "Thrombocytopenia": 11.618511580756303}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/751.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/751.json
index 19fbb170d92..a2d9f9edfbb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/751.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/751.json
@@ -1 +1 @@
-{"Diarrhoea ": 19.895343130944795, "Off label use ": 3.5755588290472957, "Vomiting ": 3.1985315533685923}
\ No newline at end of file
+{"Acute respiratory failure": 5.054972475146406, "Adenoidectomy": 117.32806557153818, "Aortic valve incompetence": 21.161389535196328, "Apnoea": 8.688030289211124, "Atelectasis": 3.986047322358089, "Bacteraemia": 4.12489650054704, "Blindness": 2.930696847597626, "Body temperature increased": 5.537805575717448, "Bone marrow transplant": 51.802174574825216, "Brain oedema": 2.815338211238017, "Bronchitis": 2.21886995164791, "Bronchospasm": 7.0777177538668345, "Cardiac arrest": 3.0666939014187347, "Cardiac disorder": 2.6926295172548267, "Cardiac failure": 2.546409433437555, "Cardiac valve disease": 26.053764349524972, "Cardio-respiratory arrest": 4.474758849921239, "Cardiomegaly": 2.968025056718841, "Carpal tunnel syndrome": 14.148462967139364, "Catheter site bruise": 596.0261588194577, "Catheter site erythema": 32.256401947237606, "Catheter site pain": 63.43451235684668, "Catheter site swelling": 60.489012398999606, "Cervical cord compression": 1075.072725692061, "Cervical spinal stenosis": 141.75257451018143, "Conductive deafness": 102.7254168767744, "Corneal opacity": 123.44992596131256, "Cough": 5.784238009981523, "Cyanosis": 14.113159405911516, "Device related infection": 28.215620515878587, "Dyspnoea": 2.187762999144732, "Ear infection": 16.14292577081708, "Ear pain": 6.819212420057196, "Ear tube insertion": 224.98271827603617, "Endotracheal intubation complication": 85.13119231268217, "Extravasation": 11.603848051508804, "Febrile infection": 134.86324540865525, "Gastrointestinal infection": 22.614233901482383, "Glaucoma": 2.1359201923771782, "Head injury": 4.805716466873002, "Heart rate increased": 2.526161159656514, "Hernia": 8.039563023613974, "Hip surgery": 18.805963814719306, "Hydrocephalus": 48.25251103409794, "Hyperreflexia": 9.1409000221061, "Hypokinesia": 2.110000820419972, "Hypotonia": 2.275360063789025, "Infection": 2.4980511055612875, "Infusion related reaction": 8.652112624932109, "Infusion site extravasation": 25.48472702528333, "Infusion site swelling": 29.761105911720964, "Inguinal hernia": 19.263277958292253, "Intracranial pressure increased": 21.1625453452651, "Intraocular pressure increased": 3.856241412791796, "Knee operation": 9.440127909780838, "Kyphosis": 47.95198316963607, "Livedo reticularis": 10.280916975096504, "Lung disorder": 2.11455468526692, "Mitral valve incompetence": 18.558064266761303, "Muscle spasticity": 4.51048855939023, "Myelopathy": 35.243267916551126, "Nasal congestion": 4.184875841004458, "Nasopharyngitis": 7.122958120782662, "Obstructive airways disorder": 5.273498934977887, "Obstructive sleep apnoea syndrome": 15.092124930041056, "Oropharyngeal pain": 4.090064569810644, "Oxygen saturation decreased": 12.78502392108105, "Pallor": 7.544964086616661, "Pharyngitis": 4.013183544048117, "Pneumonia": 8.085622593983768, "Poor venous access": 155.0225596220758, "Product administration error": 3.544226731207049, "Product dose omission issue": 3.9549973367836473, "Productive cough": 5.686594710825485, "Pulmonary hypertension": 12.240760215941242, "Pulmonary oedema": 2.429627327010325, "Quadriplegia": 23.55633315203572, "Respiratory arrest": 3.7352027350288832, "Respiratory disorder": 10.744914177809369, "Respiratory distress": 6.489544160524841, "Respiratory failure": 6.039885750628067, "Respiratory rate increased": 5.705635668774408, "Respiratory tract infection": 6.334084435864783, "Rhinorrhoea": 8.644132215498562, "Scoliosis": 7.538732418272471, "Secretion discharge": 15.197310440512474, "Seizure": 2.4324402829087965, "Skin abrasion": 7.639355211964621, "Sleep apnoea syndrome": 9.122161743484908, "Spinal cord compression": 414.2270756115629, "Spinal decompression": 380.2819896299943, "Spinal disorder": 8.843543160869503, "Spinal operation": 12.341751546978166, "Spinal pain": 3.490641462680023, "Spinal stenosis": 8.016393608331835, "Tachycardia": 2.3939423782865124, "Tachypnoea": 8.240523315057377, "Tonsillectomy": 53.80221331505649, "Tracheomalacia": 95.33772042909148, "Tracheostomy": 78.00385813281233, "Tracheostomy malfunction": 269.09333044475574, "Tricuspid valve incompetence": 6.41854196340814, "Umbilical hernia": 23.40009916876121, "Upper respiratory tract infection": 3.5069433582323035, "Urinary tract infection": 2.7146709970404883, "Vascular access complication": 102.4493073928636, "Viral infection": 5.774838559797415}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/752.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/752.json
index 33932f09673..43a7ca94647 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/752.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/752.json
@@ -1 +1 @@
-{"Constipation ": 7.257156423068888, "Diarrhoea ": 13.996441800009944, "Disease progression ": 4.555954131510183, "Hypokalaemia ": 5.145997831943793, "Malignant neoplasm progression ": 3.3445778904472245, "Off label use ": 8.550884523639548, "Prescribed underdose ": 70.74528973363854, "Product use in unapproved indication ": 3.705969482564369, "Vomiting ": 2.8160080756694805}
\ No newline at end of file
+{"Drug interaction": 34.28667812504846, "Drug withdrawal syndrome": 80.94441726232563, "Vomiting": 3.7842135647730224, "Withdrawal syndrome": 86.23155975683488}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/753.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/753.json
index ee6572d604f..c3efa843aa9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/753.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/753.json
@@ -1 +1 @@
-{"Accidental exposure to product ": 5.244019986987424, "Acute febrile neutrophilic dermatosis ": 19.18093011000357, "Acute myeloid leukaemia ": 2.970203081668104, "Acute respiratory distress syndrome ": 6.764957474492991, "Adverse drug reaction ": 3.011316265978972, "Adverse event ": 2.3149816439248965, "Application site bruise ": 69.43368450228891, "Application site haemorrhage ": 147.94494347623447, "Application site pain ": 2.804927795048449, "Application site swelling ": 2.047586347678803, "Back pain ": 2.6227792385709163, "Blood test abnormal ": 2.6430905838124468, "Body temperature abnormal ": 3.370314982099754, "Bone marrow disorder ": 6.196827253205792, "Bone marrow transplant ": 24.60955818639396, "Bone pain ": 33.27338902052712, "Breast cancer recurrent ": 8.554132483182011, "Candida infection ": 2.610466698312362, "Capillary leak syndrome ": 22.197032567138663, "Central venous catheterisation ": 20.01993553939071, "Circumstance or information capable of leading to medication error ": 2.7403140812014506, "Congenital aplasia ": 6.839830931939617, "Death ": 3.7010929026554167, "Dehydration ": 2.43310055376882, "Dementia ": 2.8494642604634706, "Device adhesion issue ": 587.2190421473565, "Device dislocation ": 145.9650241685922, "Device failure ": 10.341102686313691, "Device issue ": 19.71660762164136, "Device leakage ": 12.716821159065075, "Device malfunction ": 7.125461174583649, "Device occlusion ": 8.743292289169052, "Device use error ": 65.49996930188465, "Drug delivery system malfunction ": 3.022838220860692, "Drug dose omission by device ": 26.08128750248776, "Drug specific antibody present ": 18.032124041146933, "Febrile bone marrow aplasia ": 12.034519595265424, "Febrile infection ": 18.51688409736594, "Febrile neutropenia ": 38.821478619629374, "Full blood count abnormal ": 3.829320361628729, "Haemoglobin abnormal ": 8.205515259717526, "Hospitalisation ": 27.17484805106171, "Hydronephrosis ": 3.3233207772963778, "Incorrect disposal of product ": 91.83551177133874, "Incorrect dose administered ": 2.5005617850355657, "Incorrect dose administered by device ": 5.448923004220324, "Infection ": 2.1977624183193063, "Laboratory test abnormal ": 4.92181843772609, "Leukaemia ": 2.069665565522324, "Leukocytosis ": 22.88526447382734, "Leukopenia ": 3.3248667182508944, "Lung infiltration ": 5.287983497370491, "Lung neoplasm malignant ": 2.067877888086081, "Lymphoma ": 5.950220864120438, "Metastases to bone ": 2.0120600764763124, "Metastases to central nervous system ": 3.3168553549386783, "Metastases to lung ": 2.1302622244131606, "Metastases to lymph nodes ": 2.6874863182482165, "Mucosal inflammation ": 3.682606829417447, "Musculoskeletal chest pain ": 2.519130174600301, "Musculoskeletal pain ": 2.425379675115351, "Myelodysplastic syndrome ": 2.5998930586428264, "Neoplasm malignant ": 2.303041986971433, "Neutropenia ": 11.849121339503627, "Neutropenic sepsis ": 52.52440530302146, "Neutrophil count abnormal ": 205.1008400856755, "Neutrophil count decreased ": 6.970128398380074, "Neutrophil count increased ": 17.509674702215186, "Neutrophilia ": 7.342697582397224, "Oral candidiasis ": 2.0160950685816665, "Oral pain ": 3.890357200295511, "Ovarian cancer ": 5.034572934410719, "Pancytopenia ": 2.3144378357026536, "Pelvic pain ": 4.292131070291559, "Platelet count abnormal ": 8.719795505914457, "Product dose omission issue ": 4.381368643394172, "Product storage error ": 3.2479137331628327, "Pulmonary toxicity ": 6.231656427254602, "Radiotherapy ": 34.391378622403955, "Recurrent cancer ": 19.03528406823949, "Red blood cell count decreased ": 2.408527315012829, "Sepsis ": 4.089776122488882, "Septic shock ": 2.3741487026266617, "Skin infection ": 3.108887215642873, "Spinal pain ": 4.518070733397255, "Splenic rupture ": 64.89457263759789, "Splenomegaly ": 2.4977526448599527, "Surgery ": 3.72286271617434, "Terminal state ": 5.529934000448899, "Therapeutic response decreased ": 5.526907376088044, "Therapy non-responder ": 4.491404668802841, "Throat tightness ": 2.137882491376258, "Transfusion ": 9.371017235375414, "Unevaluable event ": 5.147706161421242, "Unintentional medical device removal ": 2200.817635316378, "White blood cell count abnormal ": 86.49372363947388, "White blood cell count decreased ": 7.939298802822751, "White blood cell count increased ": 11.990640951596411, "White blood cell disorder ": 28.4043541912802, "Wrong technique in device usage process ": 5.898162686277333, "Wrong technique in product usage process ": 14.208127611540537}
\ No newline at end of file
+{"Agitation": 2.953017410227095, "Altered state of consciousness": 4.9580686514756165, "Apnoea": 69.22507979239305, "Aspartate aminotransferase increased": 3.540408714146838, "Blood albumin decreased": 64.424764673388, "Blood potassium decreased": 14.426299324941953, "Bradypnoea": 70.86399642644066, "Brain death": 68.56268387164482, "Brain injury": 28.36220972493608, "Brain oedema": 27.452836616213578, "Cardiac arrest": 8.769090004829028, "Coma": 3.5808030444649783, "Completed suicide": 2.1268667739415084, "Confusional state": 4.6346838281898, "Depressed level of consciousness": 14.175203049477204, "Drug abuse": 5.4057542540033925, "Drug dependence": 2.240456040552168, "Drug hypersensitivity": 3.2856144298734145, "Drug interaction": 4.5710313847020485, "Drug withdrawal syndrome": 8.763207396830463, "Drug withdrawal syndrome neonatal": 15.11581335382122, "Dysarthria": 4.290598408555982, "Electrocardiogram QT prolonged": 13.492775247763587, "Emotional distress": 2.081520108533881, "Foetal exposure during pregnancy": 3.5060697833212155, "Haematocrit decreased": 15.3371753997248, "Haemoglobin decreased": 3.37101379335646, "Heart rate increased": 5.450495230275104, "Hypotension": 3.0874795075155728, "Hypoxia": 6.211441553980293, "Intentional overdose": 2.196628648644798, "Intentional product misuse": 2.365366297291258, "Irritability": 9.066761837087205, "Loss of consciousness": 4.517872845840824, "Mental status changes": 25.83439398790766, "Miosis": 65.87776609155605, "Mydriasis": 14.660874080202383, "Overdose": 18.58924069369474, "Oxygen saturation decreased": 12.214751283751784, "Pulmonary oedema": 8.184674553034494, "Pupil fixed": 95.07926110935236, "Respiratory alkalosis": 399.3790692786419, "Respiratory arrest": 14.68365083925587, "Respiratory depression": 18.967529158242627, "Respiratory failure": 3.3168000889422515, "Sedation": 20.535025536120216, "Sinus tachycardia": 37.17687997493727, "Somnolence": 3.161184862135109, "Suicide attempt": 9.202474161478769, "Toxicity to various agents": 14.069781061849614, "Unresponsive to stimuli": 53.95067868886571}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/754.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/754.json
index 42f854d4342..c2982859d47 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/754.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/754.json
@@ -1 +1 @@
-{"Balance disorder ": 5.218219641160419, "Confusional state ": 2.4794313637043484, "Delusion ": 27.76609363995252, "Drug interaction ": 2.808906238412724, "Dyskinesia ": 16.903616598255795, "Feeling abnormal ": 3.0965184283149387, "Hallucination ": 10.668591887877795, "Hallucination, visual ": 26.680345183922075, "Impulse-control disorder ": 196.8637368244121, "Muscle spasms ": 2.701126862665208, "Paraesthesia ": 3.0162274619266016, "Parkinson's disease ": 37.36175526731196, "Parkinsonism ": 49.79497931617493, "Restless legs syndrome ": 44.914537122909735, "Somnolence ": 3.7610233048737256, "Tremor ": 2.0256489370443838}
\ No newline at end of file
+{"Completed suicide": 39.61870617487866}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/755.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/755.json
index 6559e5d8078..e6e27580f68 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/755.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/755.json
@@ -1 +1 @@
-{"Blindness ": 5.224102944279429, "Blindness unilateral ": 10.516404783580237, "Blood pressure increased ": 3.242306607788607, "Cataract ": 4.195486144769688, "Chromaturia ": 8.273675765276668, "Conjunctival hyperaemia ": 29.338215224253343, "Conjunctivitis ": 8.400171226177648, "Corneal disorder ": 192.1726580425674, "Corneal epithelium defect ": 369.58054074730455, "Corneal infiltrates ": 407.96652397015856, "Corneal oedema ": 248.803231333354, "Corneal opacity ": 236.5319627352152, "Corneal perforation ": 284.4957059669732, "Corneal thinning ": 883.7926876336411, "Cystoid macular oedema ": 301.8571052958036, "Dry eye ": 17.520869235384517, "Endophthalmitis ": 66.42183283252882, "Eye discharge ": 123.80653717525392, "Eye haemorrhage ": 6.632189376763898, "Eye inflammation ": 19.05092008840178, "Eye injury ": 44.86974810301137, "Eye irritation ": 69.30522951896134, "Eye pain ": 17.243385244591956, "Eye pruritus ": 9.125705316705805, "Eye swelling ": 9.686785587428348, "Eyelid oedema ": 8.951055236548877, "Foreign body sensation in eyes ": 270.04463671168526, "Glaucoma ": 16.039538818856528, "Incorrect dose administered ": 7.133756729011886, "Incorrect product administration duration ": 26.282126748301376, "Intraocular pressure increased ": 78.22279537298262, "Iris atrophy ": 1279.1583091864472, "Keratitis ": 40.83127661989203, "Lacrimation increased ": 19.52864943822285, "Liquid product physical issue ": 251.35581652330288, "Macular oedema ": 78.65877849794477, "Medication error ": 18.067108264281742, "Musculoskeletal stiffness ": 2.323828710187012, "Ocular discomfort ": 19.42386459040564, "Ocular hyperaemia ": 36.290202634937856, "Off label use ": 3.1496315863932898, "Photophobia ": 7.93625528005635, "Poor quality product administered ": 88.73316532445071, "Product administration error ": 11.69880648177743, "Product colour issue ": 77.60008461597022, "Product container issue ": 141.15257464816798, "Product delivery mechanism issue ": 183.744377120215, "Product physical consistency issue ": 475.8685099859572, "Product quality issue ": 34.439167940621, "Product storage error ": 8.147861805313616, "Product use complaint ": 73.38824727994127, "Product use issue ": 2.934990284268869, "Punctate keratitis ": 158.59345767120948, "Sacroiliitis ": 122.89683715850722, "Swelling face ": 2.258173669718581, "Swelling of eyelid ": 17.288658040971523, "Toxic anterior segment syndrome ": 1116.2411709572875, "Ulcerative keratitis ": 439.7300494493194, "Uveitis ": 14.661846641593494, "Vision blurred ": 15.640708182897498, "Visual acuity reduced ": 32.78119662924404, "Visual impairment ": 9.143000338439425, "Vitreous floaters ": 13.201610583454848, "Wrong technique in product usage process ": 7.9308903828756705}
\ No newline at end of file
+{"Blood calcium decreased": 160.57237064988138, "Drug ineffective": 3.121134395378081, "Hypocalcaemia": 270.811839485896, "Paraesthesia": 2.9420051625843366}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/756.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/756.json
index cb49cffc72b..fcae18fb747 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/756.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/756.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 6.866572548616, "Anaemia ": 2.730300400399101, "Blood cholesterol increased ": 2.4965651509278355, "Blood lactic acid increased ": 13.854278052634928, "CD4 lymphocyte percentage decreased ": 2550.2278007409845, "CD4 lymphocytes decreased ": 60.09547117088065, "Caesarean section ": 31.671640644760345, "Cardiac failure ": 4.424284030530442, "Cardiac failure congestive ": 2.2601849228807915, "Congenital central nervous system anomaly ": 97.95426256205126, "Conjunctival hyperaemia ": 21.831025787312583, "Conjunctivitis ": 8.519764558896153, "Dehydration ": 2.9419843847535723, "Developmental delay ": 17.136368666454633, "Drug reaction with eosinophilia and systemic symptoms ": 9.589111702593245, "Drug resistance ": 6.520830090898225, "Drug-induced liver injury ": 2.3634384908254806, "Exposure during pregnancy ": 5.671149179341528, "Foetal distress syndrome ": 34.31511743597952, "Foetal exposure during pregnancy ": 12.142572455099492, "Hepatitis ": 7.86872550732801, "Hepatotoxicity ": 17.634299746053117, "Hypertriglyceridaemia ": 11.968615933076451, "Hypotension ": 3.59620508815415, "Jaundice ": 3.4900073648353533, "Lactic acidosis ": 3.561322697959865, "Large intestine infection ": 118.8266648491754, "Lipodystrophy acquired ": 30.515514340110848, "Liver function test abnormal ": 3.90455602302544, "Maternal exposure during pregnancy ": 6.852834294827379, "Pancreatitis ": 2.6717245412653083, "Pregnancy ": 24.456437645591368, "Rash ": 2.659059907965461, "Rash erythematous ": 2.9038120464215305, "Rash maculo-papular ": 6.593499741032102, "Skin exfoliation ": 13.705335866268175, "Stevens-Johnson syndrome ": 86.68310203512402, "Stillbirth ": 35.25322250807682, "Toxic epidermal necrolysis ": 42.56978628869768, "Virologic failure ": 46.82189593573251}
\ No newline at end of file
+{"Vitiligo": 830.8278739549502}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/757.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/757.json
index 3ef8b42aee4..43ed101aa75 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/757.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/757.json
@@ -1 +1 @@
-{"Abdominal abscess ": 3.4208625086148183, "Abdominal lymphadenopathy ": 14.390225556137, "Abnormal loss of weight ": 2.884630197055093, "Abscess limb ": 2.258015054011106, "Acute abdomen ": 3.1720363172057837, "Acute coronary syndrome ": 3.2599777359171687, "Acute hepatic failure ": 3.21338627833468, "Acute interstitial pneumonitis ": 10.778957736920356, "Acute myocardial infarction ": 3.304658781788562, "Alanine aminotransferase abnormal ": 4.338331987285797, "Alanine aminotransferase increased ": 4.30035839253584, "Albumin urine present ": 17.109712630113386, "Alopecia ": 3.1744523086886707, "Alpha 1 foetoprotein abnormal ": 70.07344786311162, "Alpha 1 foetoprotein increased ": 262.19548775766816, "Ammonia increased ": 12.103147509851594, "Amylase increased ": 11.204096282799698, "Anal abscess ": 3.717694595348619, "Anal fistula ": 3.8626713946848215, "Anal ulcer ": 4.795745054407323, "Aortic dissection ": 4.539225268954751, "Aphthous ulcer ": 2.2346349326458785, "Ascites ": 14.769718058471272, "Aspartate aminotransferase abnormal ": 8.290245484033543, "Aspartate aminotransferase increased ": 5.725847411890204, "Asterixis ": 5.940329626523916, "Basal ganglia haemorrhage ": 5.584904634608644, "Bile duct stone ": 3.1322955378131527, "Biliary obstruction ": 5.109036920593755, "Blister ": 4.592003870250461, "Blood albumin decreased ": 6.378044209935301, "Blood bilirubin abnormal ": 4.833402952007588, "Blood bilirubin increased ": 11.522375727930156, "Blood pressure increased ": 2.334930103542417, "Blood thyroid stimulating hormone increased ": 2.807108039778952, "Brain stem haemorrhage ": 8.327588874693083, "Brain stem infarction ": 3.117070165763841, "C-reactive protein increased ": 2.336644432733549, "Cachexia ": 4.799714315454355, "Cancer pain ": 10.26437768483618, "Cerebellar haemorrhage ": 4.653300268645264, "Cerebral haemorrhage ": 3.202158516878405, "Cerebral infarction ": 3.449978452833957, "Child-Pugh-Turcotte score increased ": 30.98701604734112, "Cholangiocarcinoma ": 4.56239475175476, "Cholangitis ": 10.43012482591973, "Cholecystitis ": 2.4764229365856085, "Cholecystitis acute ": 3.260053774123534, "Colitis ischaemic ": 2.6145519494873977, "Coma hepatic ": 24.850311588862976, "Coronary artery stenosis ": 2.170399361140439, "Death ": 2.503465724243908, "Decreased appetite ": 4.270074362743918, "Dermal cyst ": 4.526140502652323, "Dermatitis ": 3.474828196584517, "Dermatitis acneiform ": 2.313862545664453, "Dermatitis bullous ": 3.4760071191104784, "Dermatitis exfoliative ": 3.940516452845788, "Dermatitis psoriasiform ": 2.076956033137758, "Desmoid tumour ": 31.28700167329784, "Diarrhoea ": 4.365043504982423, "Disseminated intravascular coagulation ": 3.661003157919884, "Diverticular perforation ": 4.79876505324729, "Diverticulum intestinal haemorrhagic ": 2.33225968549136, "Drug eruption ": 3.1744324025329207, "Dry skin ": 4.386110742939916, "Duodenal ulcer haemorrhage ": 2.3628842627026434, "Dyslalia ": 2.755021144384417, "Dysphonia ": 6.287836771291168, "Eastern Cooperative Oncology Group performance status worsened ": 12.243618517336646, "Eating disorder ": 2.285514767836658, "Enanthema ": 6.288340282235854, "Encephalopathy ": 3.0541839438948237, "Enterocolitis ": 2.2230404333965, "Enterocolitis haemorrhagic ": 2.0096649774626254, "Epidermolysis ": 10.292004997085044, "Erythema multiforme ": 19.887232018501354, "Exfoliative rash ": 2.618476216275731, "Extremity necrosis ": 2.910304177394224, "Faeces discoloured ": 3.241241134641345, "Fistula ": 3.379818527178277, "Food refusal ": 8.308368799274705, "Furuncle ": 2.9628835777323466, "Gastric antral vascular ectasia ": 30.554153342376058, "Gastric haemorrhage ": 5.518878763099375, "Gastric ulcer ": 3.158396165668956, "Gastric ulcer haemorrhage ": 4.340003391782286, "Gastric varices haemorrhage ": 41.71983923940159, "Gastrointestinal haemorrhage ": 2.939306113624412, "Gastrointestinal perforation ": 10.247663107593302, "Gastrointestinal stromal tumour ": 2.679323249244824, "General physical health deterioration ": 3.0455009523359715, "Gingival bleeding ": 3.17010531532471, "Glossitis ": 2.618656485935144, "Haematemesis ": 4.566180596194154, "Haematochezia ": 2.065175509226473, "Haemobilia ": 55.40618228772155, "Haemoperitoneum ": 2.38478140710606, "Haemoptysis ": 5.931159267589055, "Haemothorax ": 4.453077289386711, "Hepatic cancer ": 26.53183321462419, "Hepatic cancer metastatic ": 22.59660865467791, "Hepatic cancer recurrent ": 23.004327011639884, "Hepatic cancer stage IV ": 21.91977100199012, "Hepatic cirrhosis ": 3.32044331466792, "Hepatic cyst ": 2.2306814444562675, "Hepatic encephalopathy ": 42.154087398225926, "Hepatic failure ": 11.48919229175478, "Hepatic function abnormal ": 8.49895943130735, "Hepatic infarction ": 30.31547483983686, "Hepatic lesion ": 14.791776052853082, "Hepatic mass ": 7.88935457435623, "Hepatic necrosis ": 2.176164379130741, "Hepatic neoplasm ": 4.138244583619787, "Hepatic rupture ": 77.29630421893182, "Hepatitis B reactivation ": 2.228811547482642, "Hepatitis acute ": 2.626900605097561, "Hepatitis fulminant ": 2.154395045709915, "Hepatocellular carcinoma ": 523.0707210796588, "Hepatorenal failure ": 6.587030998065674, "Hepatorenal syndrome ": 13.417094230003466, "Hiccups ": 3.107871733802602, "Hilar lymphadenopathy ": 8.536389729584071, "Hyperammonaemia ": 3.817834493446929, "Hyperamylasaemia ": 18.404690150414865, "Hyperbilirubinaemia ": 4.206334954951767, "Hyperkeratosis ": 23.754024647137253, "Hypertension ": 4.752470758247491, "Hypertransaminasaemia ": 2.3681407466998494, "Hyperuricaemia ": 2.3850677568379104, "Hypoalbuminaemia ": 4.714868488078781, "Hypocalcaemia ": 4.161016356003176, "Hypophosphataemia ": 9.03541799987023, "Hypoproteinaemia ": 3.3533500723636074, "Interstitial lung disease ": 2.0728150186380643, "Intestinal perforation ": 2.091346001228908, "Intra-abdominal haemorrhage ": 3.892114291958697, "Iron deficiency ": 2.1646648075155395, "Jaundice ": 5.969779730059007, "Jaundice cholestatic ": 6.9100771723361385, "Keratoacanthoma ": 25.238659201396885, "Lacunar infarction ": 3.2938767148953887, "Large intestinal haemorrhage ": 4.913895639642781, "Large intestine perforation ": 4.894418353014849, "Leukoencephalopathy ": 2.7692695604274853, "Lipase increased ": 5.687153491700794, "Liver abscess ": 10.125482308195616, "Liver carcinoma ruptured ": 297.61951492211045, "Liver disorder ": 4.91871587189219, "Liver function test increased ": 3.1704099325642408, "Lower gastrointestinal haemorrhage ": 4.407844073319892, "Lung abscess ": 3.4396696421049247, "Lung cancer metastatic ": 2.8190849298960323, "Lung neoplasm ": 3.069204360384449, "Lymphadenopathy mediastinal ": 10.950571625321064, "Lymphangiosis carcinomatosa ": 6.543280564162787, "Malignant ascites ": 9.704594799694252, "Malignant pleural effusion ": 7.209523246523186, "Melaena ": 5.33317546389968, "Mesenteric vein thrombosis ": 2.9009174589856137, "Metastases to abdominal cavity ": 25.96536125872216, "Metastases to adrenals ": 43.63209954533655, "Metastases to bone ": 9.928395767594251, "Metastases to central nervous system ": 4.810446488160231, "Metastases to heart ": 17.7977981189221, "Metastases to liver ": 3.053413220496524, "Metastases to lung ": 35.83003586033936, "Metastases to lymph nodes ": 11.363897750905126, "Metastases to peritoneum ": 11.751850587579357, "Metastases to pleura ": 9.428577915943851, "Metastases to spine ": 16.876739383629452, "Metastases to spleen ": 11.90556601257187, "Metastasis ": 6.630588623025816, "Metastatic renal cell carcinoma ": 8.197947416268333, "Mouth haemorrhage ": 3.678798995538519, "Mouth ulceration ": 2.2890906393397765, "Mucosal disorder ": 2.252510641610624, "Mucosal inflammation ": 4.406268651420727, "Myocardial ischaemia ": 2.83048811523868, "Nephrotic syndrome ": 7.691775605357985, "Ocular icterus ": 3.0906704393524307, "Oesophageal haemorrhage ": 5.47133373356446, "Oesophageal ulcer ": 3.5069615807318923, "Oesophageal varices haemorrhage ": 64.93929950231525, "Off label use ": 2.3037814594639823, "Oral mucosa erosion ": 6.173828220541467, "Oral pain ": 2.1853232110713425, "Osteitis ": 4.8747877273999, "Osteolysis ": 5.407297025091355, "Osteonecrosis of jaw ": 2.549461265328836, "Osteosarcoma ": 8.099751990899538, "Pain of skin ": 4.649006485479259, "Palmar erythema ": 8.540918636972627, "Palmar-plantar erythrodysaesthesia syndrome ": 119.08039126054707, "Palmoplantar keratoderma ": 44.17969983410938, "Pancreatic enzymes increased ": 16.551433861855426, "Pancreatitis acute ": 3.215301896133324, "Papillary thyroid cancer ": 9.220969723878095, "Performance status decreased ": 2.4707477031365843, "Peritonitis ": 2.4924478670896604, "Physical deconditioning ": 2.456040975280282, "Plantar erythema ": 38.92430833213189, "Platelet count decreased ": 5.221128355810861, "Pleurisy ": 2.0141032359866107, "Pneumatosis intestinalis ": 4.561519399465767, "Pneumoperitoneum ": 6.331969999942376, "Portal hypertension ": 2.409117571334489, "Portal vein thrombosis ": 10.14030283768059, "Protein induced by vitamin K absence or antagonist II increased ": 369.74579649025935, "Protein urine present ": 2.79279986788058, "Proteinuria ": 4.354487559138087, "Pulmonary mass ": 2.852158342263045, "Pulmonary tuberculosis ": 2.0155529752909755, "Pustular psoriasis ": 2.572310224818957, "Pustule ": 2.446503208664056, "Rash ": 2.4454036030821573, "Rash maculo-papular ": 2.130480555193378, "Rash papular ": 2.0587197190261666, "Reactive perforating collagenosis ": 74.97237136613865, "Renal cancer ": 3.4458437632729155, "Renal cancer metastatic ": 4.367835073890012, "Renal cell carcinoma ": 27.15587457743393, "Retinal vein thrombosis ": 3.3760254092020348, "Retroperitoneal lymphadenopathy ": 22.06095574041033, "Scrotal erythema ": 49.05166207153078, "Secondary hypertension ": 12.399022293355722, "Skin erosion ": 3.58359426885511, "Skin exfoliation ": 6.737145521819704, "Skin fissures ": 11.052755173513928, "Skin hypertrophy ": 3.13637128543387, "Skin lesion ": 2.8528256510139136, "Skin necrosis ": 2.8949519108641115, "Skin papilloma ": 2.328719717175764, "Skin reaction ": 3.3555249558991327, "Skin swelling ": 2.223583113398042, "Skin toxicity ": 19.81953950381269, "Skin ulcer ": 5.04497692804652, "Skin wound ": 3.6028465880742018, "Small intestinal haemorrhage ": 5.025707128924461, "Spontaneous bacterial peritonitis ": 11.543509920376112, "Squamous cell carcinoma ": 3.585907864689541, "Squamous cell carcinoma of skin ": 8.954914664525031, "Stevens-Johnson syndrome ": 2.570901837935917, "Stomatitis ": 4.845770834726587, "Thrombotic cerebral infarction ": 10.021200334572695, "Thyroid cancer ": 13.379094114689812, "Thyroid cancer metastatic ": 93.56880461316815, "Tongue blistering ": 2.9083840566205024, "Tongue ulceration ": 3.669896184241869, "Toxic skin eruption ": 4.024337606158823, "Tracheal haemorrhage ": 13.416407925936026, "Transaminases increased ": 3.54633526374638, "Tumour embolism ": 126.33581840400608, "Tumour haemorrhage ": 20.554212242039533, "Tumour invasion ": 15.693968202299128, "Tumour lysis syndrome ": 4.022796509248779, "Tumour marker increased ": 5.3202378299742366, "Tumour necrosis ": 22.585449187161284, "Tumour rupture ": 59.175492977968176, "Tumour thrombosis ": 148.05952665516938, "Upper gastrointestinal haemorrhage ": 2.696728308867445, "Varices oesophageal ": 6.068199854847933, "Varicose vein ruptured ": 64.65052143230412, "Weight decreased ": 2.17963390024521, "Wound dehiscence ": 3.5971583132565668, "Xerosis ": 6.102032463806109, "Yellow skin ": 2.7508372151864373}
\ No newline at end of file
+{"Anaemia": 20.56457281044169, "Anti-erythropoietin antibody positive": 816.2697011790758, "Aplasia pure red cell": 473.508449493159, "Drug ineffective": 4.217763030859302, "Drug specific antibody": 367.845356566029, "Encephalopathy": 17.58191376622502, "Haemoglobin decreased": 12.01261877135546, "Pancytopenia": 9.79841557335311, "Sudden death": 33.9341003316681, "Therapeutic response decreased": 49.68076132999248, "Thrombocytopenia": 3.402294247656699}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/758.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/758.json
index effd4ec45e5..45051c016c7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/758.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/758.json
@@ -1 +1 @@
-{"Graft loss ": 3295.829608504337, "Haemorrhage ": 13.373231443085857, "Off label use ": 7.086259099377228, "Pain ": 17.185945869110345, "Wound complication ": 689.5894839996491, "Wound infection ": 560.1063922133287}
\ No newline at end of file
+{"Corneal epithelium defect": 3128.8831920553766, "Cystoid macular oedema": 1901.787519708332, "Eye pain": 23.506506338721024, "Foreign body sensation in eyes": 629.2321277083585, "Ocular hyperaemia": 52.03467092134263, "Ulcerative keratitis": 642.186582802253, "Visual acuity reduced": 76.68996211924863}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/759.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/759.json
index 5ea47dfd5f9..ac4002f74ae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/759.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/759.json
@@ -1 +1 @@
-{"Arthralgia ": 2.6465026260726554, "Muscle discomfort ": 632.4611504205525, "Muscle spasms ": 13.794132353558789, "Myalgia ": 14.417780807854356}
\ No newline at end of file
+{"Diarrhoea": 2.33086475405779, "Hypotension": 12.733371851224328, "Pruritus": 5.702583509768984}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/76.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/76.json
index ab2aa58af24..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/76.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/76.json
@@ -1 +1 @@
-{"Live birth ": 139.48583358761417}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/760.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/760.json
index c993f499312..c4130f27ef0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/760.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/760.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 19.27922283498472, "Acute lymphocytic leukaemia recurrent ": 26.79481134470553, "Acute myocardial infarction ": 8.669747674408413, "Amylase increased ": 9.21739275793892, "Angina pectoris ": 4.542590492063399, "Arterial occlusive disease ": 10.465354402752332, "Arteriosclerosis ": 8.397776624493467, "Atrial fibrillation ": 2.66955785282084, "Blast crisis in myelogenous leukaemia ": 286.3203678106457, "Blood bilirubin increased ": 10.102352696042926, "Bone marrow failure ": 6.393172293640476, "Carotid artery stenosis ": 48.48881012128784, "Cerebral infarction ": 3.666792595541985, "Cerebrovascular accident ": 2.715151057151425, "Chronic myeloid leukaemia ": 158.3877757950397, "Chronic myeloid leukaemia recurrent ": 426.109057707447, "Chronic myeloid leukaemia transformation ": 427.7568557672759, "Coronary artery disease ": 5.716901534865498, "Coronary artery stenosis ": 41.54664126575262, "Cytogenetic analysis abnormal ": 695.3249029532374, "Cytopenia ": 20.32585334241448, "Diabetes mellitus ": 2.232325302117588, "Drug intolerance ": 12.934424257179831, "Drug resistance ": 23.846169402817285, "Dry skin ": 2.470110313204726, "Electrocardiogram QT prolonged ": 9.12100456628418, "Fluid retention ": 2.1735223635987717, "Gastrointestinal stromal tumour ": 11.736393193335884, "Haematotoxicity ": 26.942674821013792, "Hepatotoxicity ": 12.271001638090668, "Hyperbilirubinaemia ": 13.603184943644372, "Hypercholesterolaemia ": 10.103422689135725, "Intermittent claudication ": 154.9842544643605, "Ischaemic stroke ": 5.555166720576056, "Leukocytosis ": 4.618693393519429, "Lipase increased ": 16.270825269823412, "Malignant neoplasm progression ": 7.997743830252789, "Myocardial infarction ": 2.908153651936296, "Myocardial ischaemia ": 14.560143763627284, "Neutropenia ": 2.4572411260781344, "Pancreatitis ": 4.563984729764407, "Pancreatitis acute ": 4.265214066736592, "Pancytopenia ": 5.354800560503826, "Pericardial effusion ": 9.851013085097676, "Pericarditis ": 2.1593319854123867, "Peripheral arterial occlusive disease ": 250.70679987256895, "Peripheral artery occlusion ": 46.78502574437142, "Peripheral artery stenosis ": 363.3881513720295, "Peripheral vascular disorder ": 22.549931040880217, "Philadelphia chromosome positive ": 196.87095117596877, "Platelet count decreased ": 2.9466939666601366, "Pleural effusion ": 7.70811254900449, "Product use in unapproved indication ": 4.127722656021543, "Pulmonary arterial hypertension ": 6.028320894887822, "Pulmonary hypertension ": 6.39518956726823, "Second primary malignancy ": 36.12489304745866, "Skin lesion ": 2.745255098152901, "Splenomegaly ": 9.987489118933468, "Therapeutic response decreased ": 10.967238887376364, "Therapy non-responder ": 7.511798336203002, "Thrombocytopenia ": 6.080852023815987, "Thrombocytosis ": 15.432165365654727, "Transaminases increased ": 2.0239945791846257, "Treatment failure ": 5.478817510500663, "White blood cell count increased ": 3.852166419725144}
\ No newline at end of file
+{"Diarrhoea": 19.895177079409965, "Off label use": 3.5754180117525127, "Vomiting": 3.198488408966377}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/761.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/761.json
index 9b85f7623c4..27808651d93 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/761.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/761.json
@@ -1 +1 @@
-{"Acute disseminated encephalomyelitis ": 15.707706326410412, "Allergy to vaccine ": 11.163051616019644, "Angioedema ": 2.0193988998842736, "Body temperature increased ": 3.0589154877873166, "Crying ": 7.764145154594899, "Cyanosis ": 2.734425840642007, "Decreased appetite ": 2.193802118274974, "Encephalitis ": 3.7071687956924055, "Erythema ": 2.2121848386414182, "Extensive swelling of vaccinated limb ": 5.430038249084654, "Eye movement disorder ": 6.689054600506044, "Febrile convulsion ": 45.85029231307813, "Feeling of body temperature change ": 2.3880433608597538, "Gaze palsy ": 4.665709502045421, "Generalised tonic-clonic seizure ": 2.9679871469706884, "Guillain-Barre syndrome ": 2.0029548703560405, "Headache ": 2.3428405774809, "Hyperpyrexia ": 11.590817879324767, "Hypersomnia ": 4.714902671182138, "Hyperthermia ": 2.214580913911386, "Hyporesponsive to stimuli ": 18.797493621394835, "Hypotonia ": 2.367011009428384, "Hypotonic-hyporesponsive episode ": 11.353942900704736, "Immunisation reaction ": 2.48268413298265, "Induration ": 4.377577023650129, "Infant irritability ": 195.46272851523128, "Infantile vomiting ": 69.99738985663316, "Injected limb mobility decreased ": 3.33883993661782, "Injection site discomfort ": 7.488189960521683, "Injection site erythema ": 7.454712751021688, "Injection site inflammation ": 8.70069368119491, "Injection site oedema ": 4.468518269402137, "Injection site pain ": 3.148522282930843, "Injection site pruritus ": 7.378142051352186, "Injection site rash ": 3.5116178554161763, "Injection site swelling ": 7.183105379387489, "Injection site warmth ": 7.818587907676562, "Kawasaki's disease ": 22.032591417892377, "Listless ": 9.401515346152744, "Local reaction ": 6.358764998789755, "Lymphadenitis ": 4.069493574997692, "Malaise ": 2.159207342977912, "Meningism ": 16.035210660767962, "Meningitis ": 3.128265998765871, "Muscle swelling ": 11.115284585791168, "Musculoskeletal stiffness ": 2.705844199530369, "Neck pain ": 3.660534437370429, "Nuchal rigidity ": 8.053803198433927, "Opisthotonus ": 9.797976447567253, "Oropharyngeal pain ": 2.3842329799295467, "Pallor ": 8.1210327561741, "Periorbital swelling ": 3.744682457915451, "Petechiae ": 3.654132230849064, "Pharyngeal erythema ": 7.893943250534347, "Presyncope ": 5.41333610801312, "Product administered to patient of inappropriate age ": 2.834225076393344, "Pulse abnormal ": 3.518928172618143, "Pyrexia ": 4.068086107794655, "Rash erythematous ": 2.01375609417544, "Rash macular ": 2.9032586403137315, "Rash morbilliform ": 3.5595553197714955, "Rash papular ": 2.8351242440122664, "Rash vesicular ": 2.379259540249586, "Restlessness ": 2.135103420685388, "Rhinitis ": 3.795879919456345, "Screaming ": 2.726265091401973, "Seasonal allergy ": 2.3283171001890066, "Skin warm ": 2.3841906876887364, "Somnolence ": 2.4824931485470305, "Staring ": 11.444135577137825, "Syncope ": 4.397559999885228, "Tearfulness ": 5.2838289523440585, "Tonic clonic movements ": 10.97674843661849, "Tonsillitis ": 3.293398690562231, "Type 1 diabetes mellitus ": 2.885338219304841, "Unresponsive to stimuli ": 2.323760919784596, "Urticaria ": 2.612616351792876, "Vaccination site erythema ": 4.978503019292488, "Vaccination site haemorrhage ": 17.04662020251099, "Vaccination site induration ": 8.306726101960674, "Vaccination site inflammation ": 9.287959741683382, "Vaccination site joint erythema ": 12.758099906039234, "Vaccination site lymphadenopathy ": 2.793364032369446, "Vaccination site mass ": 2.783140459107506, "Vaccination site oedema ": 8.988282594334297, "Vaccination site pain ": 2.037475371541233, "Vaccination site reaction ": 3.737306260697042, "Vaccination site swelling ": 4.235572733716167, "Vaccination site warmth ": 6.25805666134014, "Vomiting ": 2.44229058626994}
\ No newline at end of file
+{"Constipation": 7.257156423068888, "Diarrhoea": 13.996324945582808, "Disease progression": 4.555954131510183, "Hypokalaemia": 5.145997831943793, "Malignant neoplasm progression": 3.3445778904472245, "Off label use": 8.550547664989967, "Prescribed underdose": 70.74528973363854, "Product use in unapproved indication": 3.705853919651488, "Vomiting": 2.815970088164797}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/762.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/762.json
index b071ebf2975..f91d9d4968f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/762.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/762.json
@@ -1 +1 @@
-{"Accidental exposure to product ": 5.489540689415383, "Adverse drug reaction ": 3.734081652832816, "Adverse event ": 3.0525515701274557, "Blood potassium decreased ": 4.419237089920904, "Cardiac disorder ": 2.1757967178613757, "Cataract ": 3.676902182580594, "Constipation ": 2.816880668151944, "Cytopenia ": 4.040620449673044, "Death ": 19.98665603141148, "Dehydration ": 3.838322056014478, "Dementia ": 2.2700589236002946, "Diarrhoea ": 3.74869922322214, "Dry skin ": 2.0652185055844936, "Fall ": 2.5957294525903687, "Full blood count abnormal ": 2.5888930296866453, "Full blood count decreased ": 24.739155655112604, "Haemoglobin decreased ": 2.0406625837343286, "Hospitalisation ": 3.901504449895852, "Illness ": 3.304630295936773, "Laboratory test abnormal ": 11.40718050355891, "Muscle spasms ": 2.0220090332138345, "Neuropathy peripheral ": 18.208848779582052, "Off label use ": 6.845788983547785, "Peripheral swelling ": 3.234383834447606, "Plasma cell myeloma ": 101.63486272063848, "Plasma cell myeloma recurrent ": 99.10039417222528, "Platelet count decreased ": 6.107446022842427, "Pneumonia ": 5.135212221689135, "Product dose omission issue ": 4.1203552947069815, "Product physical issue ": 17.10124564727359, "Red blood cell count decreased ": 2.693605988565964, "Renal disorder ": 2.223320683598701, "Rib fracture ": 3.5169239498910576, "Sepsis ": 3.438566071639955, "Thrombosis ": 2.08882954836856, "Upper respiratory tract infection ": 2.1587438697775645, "Urinary tract infection ": 2.4603594319233664, "White blood cell count decreased ": 4.675813905010871}
\ No newline at end of file
+{"Accidental exposure to product": 5.244019986987424, "Acute febrile neutrophilic dermatosis": 19.18093011000357, "Acute myeloid leukaemia": 2.970203081668104, "Acute respiratory distress syndrome": 6.764957474492991, "Adverse drug reaction": 3.011316265978972, "Adverse event": 2.3149816439248965, "Application site bruise": 69.43368450228891, "Application site haemorrhage": 147.94494347623447, "Application site pain": 2.804593177942601, "Application site swelling": 2.047586347678803, "Back pain": 2.6227792385709163, "Blood test abnormal": 2.6430905838124468, "Body temperature abnormal": 3.370314982099754, "Bone marrow disorder": 6.196827253205792, "Bone marrow transplant": 24.60955818639396, "Bone pain": 33.27338902052712, "Breast cancer recurrent": 8.554132483182011, "Candida infection": 2.610466698312362, "Capillary leak syndrome": 22.197032567138663, "Central venous catheterisation": 20.01993553939071, "Circumstance or information capable of leading to medication error": 2.7403140812014506, "Congenital aplasia": 6.818391553419278, "Death": 3.7010929026554167, "Dehydration": 2.432970435912823, "Dementia": 2.8494642604634706, "Device adhesion issue": 587.2190421473565, "Device dislocation": 145.9650241685922, "Device failure": 10.341102686313691, "Device issue": 19.71660762164136, "Device leakage": 12.716821159065075, "Device malfunction": 7.125461174583649, "Device occlusion": 8.743292289169052, "Device use error": 65.49996930188465, "Drug delivery system malfunction": 3.022838220860692, "Drug dose omission by device": 26.08128750248776, "Drug specific antibody present": 18.032124041146933, "Febrile bone marrow aplasia": 12.034519595265424, "Febrile infection": 18.51688409736594, "Febrile neutropenia": 38.821478619629374, "Full blood count abnormal": 3.829320361628729, "Haemoglobin abnormal": 8.205515259717526, "Hospitalisation": 27.17484805106171, "Hydronephrosis": 3.3233207772963778, "Incorrect disposal of product": 91.83551177133874, "Incorrect dose administered": 2.5005617850355657, "Incorrect dose administered by device": 5.448923004220324, "Infection": 2.1977624183193063, "Laboratory test abnormal": 4.92181843772609, "Leukaemia": 2.069665565522324, "Leukocytosis": 22.88526447382734, "Leukopenia": 3.324446501364178, "Lung infiltration": 5.287983497370491, "Lung neoplasm malignant": 2.067877888086081, "Lymphoma": 5.950220864120438, "Metastases to bone": 2.0120600764763124, "Metastases to central nervous system": 3.3168553549386783, "Metastases to lung": 2.1302622244131606, "Metastases to lymph nodes": 2.6874863182482165, "Mucosal inflammation": 3.682606829417447, "Musculoskeletal chest pain": 2.519130174600301, "Musculoskeletal pain": 2.425379675115351, "Myelodysplastic syndrome": 2.5998930586428264, "Neoplasm malignant": 2.303041986971433, "Neutropenia": 11.848606769773728, "Neutropenic sepsis": 52.52440530302146, "Neutrophil count abnormal": 205.1008400856755, "Neutrophil count decreased": 6.970128398380074, "Neutrophil count increased": 17.509674702215186, "Neutrophilia": 7.342697582397224, "Oral candidiasis": 2.0160950685816665, "Oral pain": 3.890357200295511, "Ovarian cancer": 5.034572934410719, "Pancytopenia": 2.3144378357026536, "Pelvic pain": 4.292131070291559, "Platelet count abnormal": 8.719795505914457, "Product dose omission issue": 4.381368643394172, "Product storage error": 3.2479137331628327, "Pulmonary toxicity": 6.231656427254602, "Radiotherapy": 34.391378622403955, "Recurrent cancer": 19.03528406823949, "Red blood cell count decreased": 2.408527315012829, "Sepsis": 4.089776122488882, "Septic shock": 2.3741487026266617, "Skin infection": 3.108887215642873, "Spinal pain": 4.518070733397255, "Splenic rupture": 64.89457263759789, "Splenomegaly": 2.4977526448599527, "Surgery": 3.72286271617434, "Terminal state": 5.529934000448899, "Therapeutic response decreased": 5.526907376088044, "Therapy non-responder": 4.491010902321075, "Throat tightness": 2.137882491376258, "Transfusion": 9.371017235375414, "Unevaluable event": 5.147706161421242, "Unintentional medical device removal": 2200.817635316378, "White blood cell count abnormal": 86.49372363947388, "White blood cell count decreased": 7.939298802822751, "White blood cell count increased": 11.988321634637789, "White blood cell disorder": 28.4043541912802, "Wrong technique in device usage process": 5.898162686277333, "Wrong technique in product usage process": 14.208127611540537}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/763.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/763.json
index a85b5dff386..94d1fad0c1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/763.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/763.json
@@ -1 +1 @@
-{"Diarrhoea ": 3.1437602900644626, "Vomiting ": 2.989973493555093}
\ No newline at end of file
+{"Balance disorder": 5.218219641160419, "Confusional state": 2.4794313637043484, "Delusion": 27.76609363995252, "Drug interaction": 2.808906238412724, "Dyskinesia": 16.903616598255795, "Feeling abnormal": 3.0964588332033385, "Hallucination": 10.668591887877795, "Hallucination, visual": 26.680345183922075, "Impulse-control disorder": 196.8637368244121, "Muscle spasms": 2.701126862665208, "Paraesthesia": 3.016199069711891, "Parkinson's disease": 37.36175526731196, "Parkinsonism": 49.79497931617493, "Restless legs syndrome": 44.914537122909735, "Somnolence": 3.760981846667725, "Tremor": 2.025572429393085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/764.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/764.json
index 4c5d4f5af15..772cf91fdbb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/764.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/764.json
@@ -1 +1 @@
-{"Drug interaction ": 29.03088900401679}
\ No newline at end of file
+{"Blindness": 5.224102944279429, "Blindness unilateral": 10.516404783580237, "Blood pressure increased": 3.2422496851796123, "Cataract": 4.195486144769688, "Chromaturia": 8.273675765276668, "Conjunctival hyperaemia": 29.338215224253343, "Conjunctivitis": 8.400171226177648, "Corneal disorder": 192.1726580425674, "Corneal epithelium defect": 369.58054074730455, "Corneal infiltrates": 407.96652397015856, "Corneal oedema": 248.803231333354, "Corneal opacity": 236.5319627352152, "Corneal perforation": 284.4957059669732, "Corneal thinning": 883.7926876336411, "Cystoid macular oedema": 301.8571052958036, "Dry eye": 17.520869235384517, "Endophthalmitis": 66.42183283252882, "Eye discharge": 123.80653717525392, "Eye haemorrhage": 6.632189376763898, "Eye inflammation": 19.05092008840178, "Eye injury": 44.86974810301137, "Eye irritation": 69.30522951896134, "Eye pain": 17.243385244591956, "Eye pruritus": 9.125705316705805, "Eye swelling": 9.686785587428348, "Eyelid oedema": 8.951055236548877, "Foreign body sensation in eyes": 270.04463671168526, "Glaucoma": 16.039538818856528, "Incorrect dose administered": 7.133756729011886, "Incorrect product administration duration": 26.282126748301376, "Intraocular pressure increased": 78.22279537298262, "Iris atrophy": 1279.1583091864472, "Keratitis": 40.83127661989203, "Lacrimation increased": 19.52864943822285, "Liquid product physical issue": 251.35581652330288, "Macular oedema": 78.65877849794477, "Medication error": 18.065808916808177, "Musculoskeletal stiffness": 2.323828710187012, "Ocular discomfort": 19.42386459040564, "Ocular hyperaemia": 36.290202634937856, "Off label use": 3.1495074886436765, "Photophobia": 7.935524251149896, "Poor quality product administered": 88.73316532445071, "Product administration error": 11.697888956126745, "Product colour issue": 77.60008461597022, "Product container issue": 141.15257464816798, "Product delivery mechanism issue": 183.744377120215, "Product physical consistency issue": 475.8685099859572, "Product quality issue": 34.439167940621, "Product storage error": 8.147861805313616, "Product use complaint": 73.38824727994127, "Product use issue": 2.934990284268869, "Punctate keratitis": 158.59345767120948, "Sacroiliitis": 122.89683715850722, "Swelling face": 2.258173669718581, "Swelling of eyelid": 17.288658040971523, "Toxic anterior segment syndrome": 1116.2411709572875, "Ulcerative keratitis": 439.7300494493194, "Uveitis": 14.661846641593494, "Vision blurred": 15.640708182897498, "Visual acuity reduced": 32.78119662924404, "Visual impairment": 9.143000338439425, "Vitreous floaters": 13.201610583454848, "Wrong technique in product usage process": 7.9308903828756705}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/765.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/765.json
index 747f1ff952e..52cc3f2466d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/765.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/765.json
@@ -1 +1 @@
-{"Drug ineffective ": 6.337790220932591, "Pleural effusion ": 19.000574397200637, "Therapy non-responder ": 40.36109660048658}
\ No newline at end of file
+{"Alanine aminotransferase increased": 6.866572548616, "Anaemia": 2.730300400399101, "Blood cholesterol increased": 2.4965651509278355, "Blood lactic acid increased": 13.854278052634928, "CD4 lymphocyte percentage decreased": 2550.2278007409845, "CD4 lymphocytes decreased": 60.09547117088065, "Caesarean section": 31.671640644760345, "Cardiac failure": 4.423880026885282, "Cardiac failure congestive": 2.260013998933977, "Congenital central nervous system anomaly": 97.95426256205126, "Conjunctival hyperaemia": 21.831025787312583, "Conjunctivitis": 8.519764558896153, "Dehydration": 2.941827322756124, "Developmental delay": 17.129683266356256, "Drug reaction with eosinophilia and systemic symptoms": 9.588319070863143, "Drug resistance": 6.520830090898225, "Drug-induced liver injury": 2.3632944586697824, "Exposure during pregnancy": 5.671149179341528, "Foetal distress syndrome": 34.31511743597952, "Foetal exposure during pregnancy": 12.142572455099492, "Hepatitis": 7.86872550732801, "Hepatotoxicity": 17.634299746053117, "Hypertriglyceridaemia": 11.968615933076451, "Hypotension": 3.5961219190881333, "Jaundice": 3.4900073648353533, "Lactic acidosis": 3.561322697959865, "Large intestine infection": 118.8266648491754, "Lipodystrophy acquired": 30.515514340110848, "Liver function test abnormal": 3.90455602302544, "Maternal exposure during pregnancy": 6.852834294827379, "Pancreatitis": 2.6717245412653083, "Pregnancy": 24.456437645591368, "Rash": 2.6590233715161964, "Rash erythematous": 2.9038120464215305, "Rash maculo-papular": 6.593499741032102, "Skin exfoliation": 13.705335866268175, "Stevens-Johnson syndrome": 86.68310203512402, "Stillbirth": 35.25322250807682, "Toxic epidermal necrolysis": 42.56978628869768, "Virologic failure": 46.82189593573251}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/766.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/766.json
index 1293d887d27..422b2d33e69 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/766.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/766.json
@@ -1 +1 @@
-{"Back pain ": 6.015607359172312, "Bone pain ": 40.68673118342683, "Drug ineffective ": 2.88515984082921, "Erythema ": 4.622935345100571, "Febrile neutropenia ": 6.590292384945143, "Neutropenia ": 8.226211923625936, "Neutrophil count decreased ": 10.95394276252234, "Pruritus ": 2.741177310082855, "Therapy non-responder ": 16.099585110706617, "Thrombocytopenia ": 2.720000603483483, "Urticaria ": 2.451921111089596}
\ No newline at end of file
+{"Abdominal abscess": 3.4208625086148183, "Abdominal lymphadenopathy": 14.390225556137, "Abnormal loss of weight": 2.884630197055093, "Abscess limb": 2.258015054011106, "Acute abdomen": 3.1720363172057837, "Acute coronary syndrome": 3.2599777359171687, "Acute hepatic failure": 3.21338627833468, "Acute interstitial pneumonitis": 10.778957736920356, "Acute myocardial infarction": 3.304658781788562, "Alanine aminotransferase abnormal": 4.338331987285797, "Alanine aminotransferase increased": 4.30035839253584, "Albumin urine present": 17.109712630113386, "Alopecia": 3.1744523086886707, "Alpha 1 foetoprotein abnormal": 70.07344786311162, "Alpha 1 foetoprotein increased": 262.19548775766816, "Ammonia increased": 12.103147509851594, "Amylase increased": 11.204096282799698, "Anal abscess": 3.717694595348619, "Anal fistula": 3.8626713946848215, "Anal ulcer": 4.795745054407323, "Aortic dissection": 4.539225268954751, "Aphthous ulcer": 2.2346349326458785, "Ascites": 14.769718058471272, "Aspartate aminotransferase abnormal": 8.290245484033543, "Aspartate aminotransferase increased": 5.725847411890204, "Asterixis": 5.940329626523916, "Basal ganglia haemorrhage": 5.584904634608644, "Bile duct stone": 3.1322955378131527, "Biliary obstruction": 5.109036920593755, "Blister": 4.592003870250461, "Blood albumin decreased": 6.378044209935301, "Blood bilirubin abnormal": 4.833402952007588, "Blood bilirubin increased": 11.522375727930156, "Blood pressure increased": 2.3348888331550754, "Blood thyroid stimulating hormone increased": 2.807108039778952, "Brain stem haemorrhage": 8.327588874693083, "Brain stem infarction": 3.117070165763841, "C-reactive protein increased": 2.336644432733549, "Cachexia": 4.799714315454355, "Cancer pain": 10.26437768483618, "Cerebellar haemorrhage": 4.653300268645264, "Cerebral haemorrhage": 3.202158516878405, "Cerebral infarction": 3.449978452833957, "Child-Pugh-Turcotte score increased": 30.98701604734112, "Cholangiocarcinoma": 4.56239475175476, "Cholangitis": 10.43012482591973, "Cholecystitis": 2.4764229365856085, "Cholecystitis acute": 3.260053774123534, "Colitis ischaemic": 2.6145519494873977, "Coma hepatic": 24.850311588862976, "Coronary artery stenosis": 2.170399361140439, "Death": 2.503465724243908, "Decreased appetite": 4.270032408109893, "Dermal cyst": 4.526140502652323, "Dermatitis": 3.474368779543348, "Dermatitis acneiform": 2.313862545664453, "Dermatitis bullous": 3.4760071191104784, "Dermatitis exfoliative": 3.940516452845788, "Dermatitis psoriasiform": 2.076956033137758, "Desmoid tumour": 31.28700167329784, "Diarrhoea": 4.365006597416798, "Disseminated intravascular coagulation": 3.661003157919884, "Diverticular perforation": 4.79876505324729, "Diverticulum intestinal haemorrhagic": 2.33225968549136, "Drug eruption": 3.1744324025329207, "Dry skin": 4.386110742939916, "Duodenal ulcer haemorrhage": 2.3628842627026434, "Dyslalia": 2.755021144384417, "Dysphonia": 6.287836771291168, "Eastern Cooperative Oncology Group performance status worsened": 12.243618517336646, "Eating disorder": 2.285514767836658, "Enanthema": 6.288340282235854, "Encephalopathy": 3.0541839438948237, "Enterocolitis": 2.2230404333965, "Enterocolitis haemorrhagic": 2.0096649774626254, "Epidermolysis": 10.292004997085044, "Erythema multiforme": 19.887232018501354, "Exfoliative rash": 2.618476216275731, "Extremity necrosis": 2.910304177394224, "Faeces discoloured": 3.241241134641345, "Fistula": 3.379818527178277, "Food refusal": 8.283540374489354, "Furuncle": 2.9628835777323466, "Gastric antral vascular ectasia": 30.554153342376058, "Gastric haemorrhage": 5.518878763099375, "Gastric ulcer": 3.156276516354088, "Gastric ulcer haemorrhage": 4.340003391782286, "Gastric varices haemorrhage": 41.71983923940159, "Gastrointestinal haemorrhage": 2.939306113624412, "Gastrointestinal perforation": 10.247663107593302, "Gastrointestinal stromal tumour": 2.679323249244824, "General physical health deterioration": 3.0455009523359715, "Gingival bleeding": 3.17010531532471, "Glossitis": 2.618656485935144, "Haematemesis": 4.565769928899651, "Haematochezia": 2.064970027477269, "Haemobilia": 55.40618228772155, "Haemoperitoneum": 2.38478140710606, "Haemoptysis": 5.931159267589055, "Haemothorax": 4.453077289386711, "Hepatic cancer": 26.53183321462419, "Hepatic cancer metastatic": 22.59660865467791, "Hepatic cancer recurrent": 23.004327011639884, "Hepatic cancer stage IV": 21.91977100199012, "Hepatic cirrhosis": 3.32044331466792, "Hepatic cyst": 2.2306814444562675, "Hepatic encephalopathy": 42.154087398225926, "Hepatic failure": 11.48919229175478, "Hepatic function abnormal": 8.49895943130735, "Hepatic infarction": 30.31547483983686, "Hepatic lesion": 14.791776052853082, "Hepatic mass": 7.88935457435623, "Hepatic necrosis": 2.176164379130741, "Hepatic neoplasm": 4.138244583619787, "Hepatic rupture": 77.29630421893182, "Hepatitis B reactivation": 2.228811547482642, "Hepatitis acute": 2.626900605097561, "Hepatitis fulminant": 2.154395045709915, "Hepatocellular carcinoma": 523.0707210796588, "Hepatorenal failure": 6.587030998065674, "Hepatorenal syndrome": 13.417094230003466, "Hiccups": 3.107871733802602, "Hilar lymphadenopathy": 8.536389729584071, "Hyperammonaemia": 3.817834493446929, "Hyperamylasaemia": 18.404690150414865, "Hyperbilirubinaemia": 4.206334954951767, "Hyperkeratosis": 23.754024647137253, "Hypertension": 4.752420990057066, "Hypertransaminasaemia": 2.3681407466998494, "Hyperuricaemia": 2.3850677568379104, "Hypoalbuminaemia": 4.714868488078781, "Hypocalcaemia": 4.161016356003176, "Hypophosphataemia": 9.03541799987023, "Hypoproteinaemia": 3.3533500723636074, "Interstitial lung disease": 2.0728150186380643, "Intestinal perforation": 2.091346001228908, "Intra-abdominal haemorrhage": 3.892114291958697, "Iron deficiency": 2.1646648075155395, "Jaundice": 5.969779730059007, "Jaundice cholestatic": 6.9100771723361385, "Keratoacanthoma": 24.94634059531697, "Lacunar infarction": 3.2938767148953887, "Large intestinal haemorrhage": 4.913895639642781, "Large intestine perforation": 4.894418353014849, "Leukoencephalopathy": 2.7692695604274853, "Lipase increased": 5.687153491700794, "Liver abscess": 10.125482308195616, "Liver carcinoma ruptured": 297.61951492211045, "Liver disorder": 4.91871587189219, "Liver function test increased": 3.1704099325642408, "Lower gastrointestinal haemorrhage": 4.407844073319892, "Lung abscess": 3.4396696421049247, "Lung cancer metastatic": 2.8190849298960323, "Lung neoplasm": 3.069204360384449, "Lymphadenopathy mediastinal": 10.950571625321064, "Lymphangiosis carcinomatosa": 6.543280564162787, "Malignant ascites": 9.704594799694252, "Malignant pleural effusion": 7.209523246523186, "Melaena": 5.33247663245497, "Mesenteric vein thrombosis": 2.9009174589856137, "Metastases to abdominal cavity": 25.96536125872216, "Metastases to adrenals": 43.63209954533655, "Metastases to bone": 9.928395767594251, "Metastases to central nervous system": 4.810446488160231, "Metastases to heart": 17.7977981189221, "Metastases to liver": 3.053413220496524, "Metastases to lung": 35.83003586033936, "Metastases to lymph nodes": 11.363897750905126, "Metastases to peritoneum": 11.751850587579357, "Metastases to pleura": 9.428577915943851, "Metastases to spine": 16.876739383629452, "Metastases to spleen": 11.90556601257187, "Metastasis": 6.630588623025816, "Metastatic renal cell carcinoma": 8.197947416268333, "Mouth haemorrhage": 3.678798995538519, "Mouth ulceration": 2.2890906393397765, "Mucosal disorder": 2.252510641610624, "Mucosal inflammation": 4.406268651420727, "Myocardial ischaemia": 2.83048811523868, "Nephrotic syndrome": 7.691775605357985, "Ocular icterus": 3.0906704393524307, "Oesophageal haemorrhage": 5.47133373356446, "Oesophageal ulcer": 3.5069615807318923, "Oesophageal varices haemorrhage": 64.93929950231525, "Off label use": 2.303690090996479, "Oral mucosa erosion": 6.173828220541467, "Oral pain": 2.1853232110713425, "Osteitis": 4.8747877273999, "Osteolysis": 5.407297025091355, "Osteonecrosis of jaw": 2.549461265328836, "Osteosarcoma": 8.099751990899538, "Pain of skin": 4.648384947905295, "Palmar erythema": 8.540918636972627, "Palmar-plantar erythrodysaesthesia syndrome": 119.08039126054707, "Palmoplantar keratoderma": 44.17969983410938, "Pancreatic enzymes increased": 16.551433861855426, "Pancreatitis acute": 3.215301896133324, "Papillary thyroid cancer": 9.220969723878095, "Performance status decreased": 2.4707477031365843, "Peritonitis": 2.4924478670896604, "Physical deconditioning": 2.456040975280282, "Plantar erythema": 38.92430833213189, "Platelet count decreased": 5.221128355810861, "Pleurisy": 2.0141032359866107, "Pneumatosis intestinalis": 4.561519399465767, "Pneumoperitoneum": 6.331969999942376, "Portal hypertension": 2.409117571334489, "Portal vein thrombosis": 10.14030283768059, "Protein induced by vitamin K absence or antagonist II increased": 369.74579649025935, "Protein urine present": 2.79279986788058, "Proteinuria": 4.354487559138087, "Pulmonary mass": 2.852158342263045, "Pulmonary tuberculosis": 2.0155529752909755, "Pustular psoriasis": 2.572310224818957, "Pustule": 2.446503208664056, "Rash": 2.445369764512457, "Rash maculo-papular": 2.130480555193378, "Rash papular": 2.0584908497861383, "Reactive perforating collagenosis": 74.97237136613865, "Renal cancer": 3.4458437632729155, "Renal cancer metastatic": 4.367835073890012, "Renal cell carcinoma": 27.15587457743393, "Retinal vein thrombosis": 3.3760254092020348, "Retroperitoneal lymphadenopathy": 22.06095574041033, "Scrotal erythema": 49.05166207153078, "Secondary hypertension": 12.399022293355722, "Skin erosion": 3.58359426885511, "Skin exfoliation": 6.737145521819704, "Skin fissures": 11.052755173513928, "Skin hypertrophy": 3.13637128543387, "Skin lesion": 2.8528256510139136, "Skin necrosis": 2.8949519108641115, "Skin papilloma": 2.328719717175764, "Skin reaction": 3.3555249558991327, "Skin swelling": 2.223583113398042, "Skin toxicity": 19.789406420087783, "Skin ulcer": 5.04497692804652, "Skin wound": 3.6028465880742018, "Small intestinal haemorrhage": 5.025707128924461, "Spontaneous bacterial peritonitis": 11.543509920376112, "Squamous cell carcinoma": 3.585907864689541, "Squamous cell carcinoma of skin": 8.954914664525031, "Stevens-Johnson syndrome": 2.570901837935917, "Stomatitis": 4.845770834726587, "Thrombotic cerebral infarction": 10.021200334572695, "Thyroid cancer": 13.379094114689812, "Thyroid cancer metastatic": 93.56880461316815, "Tongue blistering": 2.9083840566205024, "Tongue ulceration": 3.669896184241869, "Toxic skin eruption": 4.024337606158823, "Tracheal haemorrhage": 13.416407925936026, "Transaminases increased": 3.54611574032456, "Tumour embolism": 126.33581840400608, "Tumour haemorrhage": 20.554212242039533, "Tumour invasion": 15.693968202299128, "Tumour lysis syndrome": 4.022796509248779, "Tumour marker increased": 5.3202378299742366, "Tumour necrosis": 22.585449187161284, "Tumour rupture": 59.175492977968176, "Tumour thrombosis": 148.05952665516938, "Upper gastrointestinal haemorrhage": 2.695990227548082, "Varices oesophageal": 6.068199854847933, "Varicose vein ruptured": 64.65052143230412, "Weight decreased": 2.17963390024521, "Wound dehiscence": 3.5971583132565668, "Xerosis": 6.102032463806109, "Yellow skin": 2.7508372151864373}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/767.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/767.json
index f53b13bdaf4..2e2ff082db3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/767.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/767.json
@@ -1 +1 @@
-{"Autoimmune colitis ": 277.12504022806064, "Autoimmune hepatitis ": 17.757873940261966, "Colitis ": 19.19143562446282, "Cytokine release syndrome ": 9.860012062117296, "Diarrhoea ": 2.1930670218441155, "Disease progression ": 2.9191940395170746, "Disseminated intravascular coagulation ": 6.418862853447184, "Febrile neutropenia ": 4.432164173693639, "General physical health deterioration ": 3.6289708757655954, "Hepatitis ": 8.061960965788677, "Hyperthyroidism ": 13.778586527824569, "Hypophysitis ": 43.84328165206169, "Hypothyroidism ": 9.037974754439654, "Hypoxia ": 6.673028803452018, "Immune effector cell-associated neurotoxicity syndrome ": 29.267269951826894, "Immune-mediated enterocolitis ": 19.27855314949008, "Immune-mediated lung disease ": 43.27989002890576, "Intentional product use issue ": 15.92180494662868, "Interstitial lung disease ": 6.806957161231257, "Liver disorder ": 3.7817380314767433, "Malignant neoplasm progression ": 16.770999437033964, "Myelosuppression ": 2.816398540645348, "Myocarditis ": 2.2610322161649843, "Neuropathy peripheral ": 4.59289338589455, "Neutrophil count decreased ": 3.914067922108416, "Off label use ": 2.507685124925671, "Pemphigoid ": 8.241259495879213, "Platelet count decreased ": 2.244857411606162, "Pneumonia aspiration ": 8.820163313211008, "Pneumonitis ": 12.63028930487864, "Rash maculo-papular ": 3.2160327820643664, "Thyroiditis ": 22.22660525458709, "Transaminases increased ": 3.407062401391325, "Tubulointerstitial nephritis ": 12.28610223157174, "White blood cell count decreased ": 2.8638986780071414}
\ No newline at end of file
+{"Graft loss": 3295.829608504337, "Haemorrhage": 13.373231443085857, "Off label use": 7.085979998500701, "Pain": 17.18579976441209, "Wound complication": 685.2061884811179, "Wound infection": 560.1063922133287}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/768.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/768.json
index 043f12b3743..09801fd6bab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/768.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/768.json
@@ -1 +1 @@
-{"Acute kidney injury ": 12.206761895527944, "Atrial fibrillation ": 6.665321115464096, "Hyperkalaemia ": 11.223407434579828, "Hypotension ": 9.320587689618486}
\ No newline at end of file
+{"Arthralgia": 2.6465026260726554, "Muscle discomfort": 632.4611504205525, "Muscle spasms": 13.794132353558789, "Myalgia": 14.417780807854356}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/769.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/769.json
index 3df83695419..a1b70371cc4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/769.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/769.json
@@ -1 +1 @@
-{"Crying ": 35.775660033151794, "Pyrexia ": 2.3064283102326253, "Rash ": 2.4208877249915446}
\ No newline at end of file
+{"Acute coronary syndrome": 19.27922283498472, "Acute lymphocytic leukaemia recurrent": 26.79481134470553, "Acute myocardial infarction": 8.669747674408413, "Amylase increased": 9.21739275793892, "Angina pectoris": 4.542590492063399, "Arterial occlusive disease": 10.465354402752332, "Arteriosclerosis": 8.397776624493467, "Atrial fibrillation": 2.6694849604675825, "Blast crisis in myelogenous leukaemia": 286.3203678106457, "Blood bilirubin increased": 10.102352696042926, "Bone marrow failure": 6.393172293640476, "Carotid artery stenosis": 48.48881012128784, "Cerebral infarction": 3.666792595541985, "Cerebrovascular accident": 2.7151021093833347, "Chronic myeloid leukaemia": 158.3877757950397, "Chronic myeloid leukaemia recurrent": 426.109057707447, "Chronic myeloid leukaemia transformation": 427.7568557672759, "Coronary artery disease": 5.716901534865498, "Coronary artery stenosis": 41.54664126575262, "Cytogenetic analysis abnormal": 695.3249029532374, "Cytopenia": 20.309626323558398, "Diabetes mellitus": 2.232325302117588, "Drug intolerance": 12.934424257179831, "Drug resistance": 23.846169402817285, "Dry skin": 2.470110313204726, "Electrocardiogram QT prolonged": 9.12100456628418, "Fluid retention": 2.1735223635987717, "Gastrointestinal stromal tumour": 11.736393193335884, "Haematotoxicity": 26.942674821013792, "Hepatotoxicity": 12.271001638090668, "Hyperbilirubinaemia": 13.603184943644372, "Hypercholesterolaemia": 10.103422689135725, "Intermittent claudication": 154.9842544643605, "Ischaemic stroke": 5.555166720576056, "Leukocytosis": 4.618693393519429, "Lipase increased": 16.270825269823412, "Malignant neoplasm progression": 7.997743830252789, "Myocardial infarction": 2.908153651936296, "Myocardial ischaemia": 14.560143763627284, "Neutropenia": 2.457135422750263, "Pancreatitis": 4.563984729764407, "Pancreatitis acute": 4.265214066736592, "Pancytopenia": 5.354800560503826, "Pericardial effusion": 9.851013085097676, "Pericarditis": 2.1593319854123867, "Peripheral arterial occlusive disease": 250.70679987256895, "Peripheral artery occlusion": 46.78502574437142, "Peripheral artery stenosis": 363.3881513720295, "Peripheral vascular disorder": 22.549931040880217, "Philadelphia chromosome positive": 196.87095117596877, "Platelet count decreased": 2.9466939666601366, "Pleural effusion": 7.7074018838655425, "Product use in unapproved indication": 4.127593840182777, "Pulmonary arterial hypertension": 6.028320894887822, "Pulmonary hypertension": 6.39518956726823, "Second primary malignancy": 36.12489304745866, "Skin lesion": 2.745255098152901, "Splenomegaly": 9.987489118933468, "Therapeutic response decreased": 10.967238887376364, "Therapy non-responder": 7.511141308791527, "Thrombocytopenia": 6.0802793347092505, "Thrombocytosis": 15.432165365654727, "Transaminases increased": 2.0238706312866928, "Treatment failure": 5.478817510500663, "White blood cell count increased": 3.851428504206577}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/77.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/77.json
index 436df79ac1a..916488cbb6b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/77.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/77.json
@@ -1 +1 @@
-{"Acute kidney injury ": 9.00567855366251, "Completed suicide ": 35.925444641320624, "Drug ineffective ": 2.2254407225223947, "Toxicity to various agents ": 16.31705215644659}
\ No newline at end of file
+{"Live birth": 139.48583358761417}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/770.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/770.json
index e3cc7eab524..ad649426ba9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/770.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/770.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 7.254318368077092, "Acute kidney injury ": 5.211057898454889, "Adrenal insufficiency ": 12.192195844638164, "Adverse event ": 2.237508494936895, "Atrioventricular septal defect ": 156.6128739519058, "Blood bilirubin increased ": 9.56020195014718, "Blood creatine phosphokinase increased ": 2.002202934435132, "Blood creatinine increased ": 2.241142161003636, "Blood phosphorus decreased ": 24.19163771582701, "Blood triglycerides increased ": 3.241793039219291, "Caesarean section ": 37.7469176081207, "Calculus urinary ": 112.9198028176019, "Cell death ": 34.658507580573975, "Cervical incompetence ": 116.0334952499294, "Cholecystitis ": 6.794073087952374, "Cholelithiasis ": 9.640760788165757, "Cholestasis ": 8.065466469323013, "Congenital bowing of long bones ": 532.2562342398328, "Conjunctivitis ": 2.0567808723047305, "Coronary artery occlusion ": 4.184810950196142, "Cortisol decreased ": 34.022475760079764, "Cushing's syndrome ": 147.495289442233, "Cushingoid ": 70.86810849352483, "Drug interaction ": 7.566770834400439, "Drug level decreased ": 5.582330660875571, "Drug level increased ": 2.8310270506297863, "Drug reaction with eosinophilia and systemic symptoms ": 5.079185470480707, "Drug withdrawal syndrome neonatal ": 4.830257194988777, "Dyslipidaemia ": 22.02834438013721, "End stage renal disease ": 2.6632980671724806, "Eosinophilia ": 2.248148411607312, "Exposure during pregnancy ": 6.037017700391125, "Eye disorder ": 2.056079777300712, "Eyelid oedema ": 4.209716842282538, "Fanconi syndrome ": 65.88646132650825, "Fanconi syndrome acquired ": 13.237790094603763, "Foetal death ": 9.983281402854429, "Foetal exposure during pregnancy ": 10.133152246833808, "Foetal growth restriction ": 11.290556341965608, "Gestational diabetes ": 28.894697793690543, "Glycosuria ": 13.658677211931511, "Gynaecomastia ": 3.833056649095538, "HIV infection ": 27.34268683994153, "Haemolytic anaemia ": 2.356238692080797, "Heart disease congenital ": 22.051945591775198, "Hepatic cytolysis ": 17.42151593690474, "Hepatic enzyme increased ": 3.0386557845788955, "Hepatic steatosis ": 5.292626917247405, "Hepatitis ": 6.5386685202581765, "Hepatitis C ": 2.3846614160916837, "Hepatotoxicity ": 2.034388551964605, "Heterotaxia ": 182.35772313239215, "Hydronephrosis ": 19.56728830786064, "Hyperbilirubinaemia ": 42.8540899561524, "Hypercapnia ": 12.482923692416897, "Hypercholesterolaemia ": 3.832174146612736, "Hypophosphataemia ": 9.305293571570456, "Immune reconstitution inflammatory syndrome ": 36.19482630371997, "Jaundice ": 17.575446734860776, "Lactic acidosis ": 2.1900375161912287, "Lipodystrophy acquired ": 51.442515404716, "Lipohypertrophy ": 60.87722005330464, "Live birth ": 25.246827942120824, "Low birth weight baby ": 3.490716487831572, "Lymphoma ": 7.656605140753281, "Maternal exposure during pregnancy ": 6.9877197980120105, "Metabolic acidosis ": 2.035549662981824, "Mycobacterium avium complex infection ": 13.744392662934828, "Myoglobin blood increased ": 19.64221659720473, "Nephrolithiasis ": 24.02392613476737, "Nephropathy toxic ": 5.664561806643916, "Neuropathy peripheral ": 2.1148123957168536, "Normal newborn ": 16.84186026990361, "Ocular icterus ": 41.01902061840364, "Oedema ": 2.0137407408963885, "Oral candidiasis ": 3.1838893230475063, "Osteonecrosis ": 2.3158143652694068, "Osteoporosis ": 6.157647300067522, "Pancreatitis ": 3.62235554795027, "Pancreatitis acute ": 2.147938191645139, "Pancreatitis necrotising ": 14.842834958997877, "Patent ductus arteriosus ": 14.95502870289387, "Peripheral motor neuropathy ": 36.550546887176736, "Peripheral sensory neuropathy ": 7.426022793299137, "Polyneuropathy ": 5.739199544723217, "Pregnancy ": 19.068601939595894, "Pregnancy on contraceptive ": 58.381615201498406, "Premature baby ": 7.138323483931827, "Premature delivery ": 9.566251248974568, "Premature labour ": 18.05163915933248, "Premature rupture of membranes ": 36.794002436428336, "Proteinuria ": 7.953206706559948, "Rash macular ": 2.1732448113742127, "Rash maculo-papular ": 6.381747973221551, "Renal colic ": 126.2362430253976, "Renal failure ": 2.4082603796219657, "Renal tubular acidosis ": 32.84003602602806, "Renal tubular disorder ": 79.18725397218712, "Renal tubular necrosis ": 6.1356269078419645, "Rhabdomyolysis ": 3.186967632131719, "Rib fracture ": 2.2766374056063348, "Spinal compression fracture ": 8.421295783284583, "Stillbirth ": 18.583614530309685, "Toxic skin eruption ": 6.115183930949762, "Transaminases increased ": 4.016448649399696, "Tubulointerstitial nephritis ": 4.546324602029553, "Type 1 diabetes mellitus ": 3.2835210247272197, "Uveitis ": 7.044802104637939, "Ventricular fibrillation ": 2.601898624979444, "Ventricular septal defect ": 16.849989176550306, "Viral load increased ": 18.752262737242443}
\ No newline at end of file
+{"Acute disseminated encephalomyelitis": 15.707706326410412, "Allergy to vaccine": 11.163051616019644, "Angioedema": 2.0193988998842736, "Body temperature increased": 3.0589154877873166, "Crying": 7.762347387416658, "Cyanosis": 2.7339146832721126, "Decreased appetite": 2.193780796886408, "Encephalitis": 3.7071687956924055, "Erythema": 2.2121631584371286, "Extensive swelling of vaccinated limb": 5.430038249084654, "Eye movement disorder": 6.689054600506044, "Febrile convulsion": 45.83363642889816, "Feeling of body temperature change": 2.3880433608597538, "Gaze palsy": 4.665709502045421, "Generalised tonic-clonic seizure": 2.9679871469706884, "Guillain-Barre syndrome": 2.0029548703560405, "Headache": 2.342826760234477, "Hyperpyrexia": 11.590817879324767, "Hypersomnia": 4.714902671182138, "Hyperthermia": 2.214580913911386, "Hyporesponsive to stimuli": 18.797493621394835, "Hypotonia": 2.36675622570285, "Hypotonic-hyporesponsive episode": 11.353942900704736, "Immunisation reaction": 2.48268413298265, "Induration": 4.377577023650129, "Infant irritability": 195.46272851523128, "Infantile vomiting": 69.99738985663316, "Injected limb mobility decreased": 3.33883993661782, "Injection site discomfort": 7.488189960521683, "Injection site erythema": 7.454712751021688, "Injection site inflammation": 8.70069368119491, "Injection site oedema": 4.467100311926894, "Injection site pain": 3.148482722205645, "Injection site pruritus": 7.378142051352186, "Injection site rash": 3.5116178554161763, "Injection site swelling": 7.183105379387489, "Injection site warmth": 7.818587907676562, "Kawasaki's disease": 21.98349545687021, "Listless": 9.401515346152744, "Local reaction": 6.358764998789755, "Lymphadenitis": 4.068550207702908, "Malaise": 2.159179721533808, "Meningism": 16.035210660767962, "Meningitis": 3.128265998765871, "Muscle swelling": 11.115284585791168, "Musculoskeletal stiffness": 2.705844199530369, "Neck pain": 3.660534437370429, "Nuchal rigidity": 8.053803198433927, "Opisthotonus": 9.797976447567253, "Oropharyngeal pain": 2.3842329799295467, "Pallor": 8.120515377750237, "Periorbital swelling": 3.744682457915451, "Petechiae": 3.654132230849064, "Pharyngeal erythema": 7.893943250534347, "Presyncope": 5.41333610801312, "Product administered to patient of inappropriate age": 2.834225076393344, "Pulse abnormal": 3.518928172618143, "Pyrexia": 4.067998903234543, "Rash erythematous": 2.01375609417544, "Rash macular": 2.9032586403137315, "Rash morbilliform": 3.5595553197714955, "Rash papular": 2.8348102637919945, "Rash vesicular": 2.379259540249586, "Restlessness": 2.1349906125743776, "Rhinitis": 3.795879919456345, "Screaming": 2.726265091401973, "Seasonal allergy": 2.3283171001890066, "Skin warm": 2.3841906876887364, "Somnolence": 2.482465722244535, "Staring": 11.444135577137825, "Syncope": 4.397499233043477, "Tearfulness": 5.2838289523440585, "Tonic clonic movements": 10.97674843661849, "Tonsillitis": 3.293398690562231, "Type 1 diabetes mellitus": 2.885338219304841, "Unresponsive to stimuli": 2.323504947777582, "Urticaria": 2.6125895213199795, "Vaccination site erythema": 4.978503019292488, "Vaccination site haemorrhage": 17.04662020251099, "Vaccination site induration": 8.306726101960674, "Vaccination site inflammation": 9.287959741683382, "Vaccination site joint erythema": 12.758099906039234, "Vaccination site lymphadenopathy": 2.793364032369446, "Vaccination site mass": 2.783140459107506, "Vaccination site oedema": 8.988282594334297, "Vaccination site pain": 2.037475371541233, "Vaccination site reaction": 3.737095393930247, "Vaccination site swelling": 4.235572733716167, "Vaccination site warmth": 6.25805666134014, "Vomiting": 2.4422575671746856}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/771.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/771.json
index 14d4ca7d5d8..34173295afb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/771.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/771.json
@@ -1 +1 @@
-{"Adverse event ": 3.590686376299836, "Angina unstable ": 4.239119553640717, "Apnoea ": 2.2698479644444087, "Atelectasis ": 3.1221692277212894, "Autism spectrum disorder ": 14.291885322595691, "Bacterial infection ": 2.682976584492553, "Blood potassium increased ": 2.2236532236778337, "Body temperature decreased ": 3.2569288712147344, "Bundle branch block left ": 7.8619749980933635, "Candida infection ": 2.76320646320378, "Cardiac arrest ": 4.020238732148068, "Cardio-respiratory arrest ": 5.563850512307703, "Clostridium difficile colitis ": 6.956412937382509, "Completed suicide ": 14.45282963815395, "Crying ": 4.117310786986261, "Cyanosis ": 4.385067069084985, "Cytomegalovirus infection ": 3.03590129454706, "Deafness neurosensory ": 12.530174202446329, "Dehydration ": 2.349773240712988, "Dermatitis contact ": 4.870256629086287, "Drug abuse ": 8.004700452066203, "Drug interaction ": 2.227006661370445, "Drug-induced liver injury ": 2.1596278797698503, "Dysstasia ": 2.2321176366612145, "Encephalopathy ": 2.511557103640587, "Eosinophil count increased ": 2.407488415386257, "Febrile convulsion ": 4.226643834834412, "Febrile neutropenia ": 2.598327012138187, "Haemolytic anaemia ": 2.4442927886467456, "Hepatic artery stenosis ": 316.24411147327004, "Hepatic function abnormal ": 2.731961783495609, "Herpes zoster ": 2.548771515691624, "Hyperlipidaemia ": 3.158938388842871, "Hypotonia ": 4.338967905265661, "Hypotonic-hyporesponsive episode ": 20.812459476653828, "Micturition urgency ": 3.395840337597743, "Nervous system disorder ": 4.132229480147723, "Ophthalmic herpes zoster ": 5.990997569429214, "Overdose ": 5.136330255025773, "Pallor ": 3.717125591331736, "Poisoning ": 3.0863450055831905, "Post herpetic neuralgia ": 9.798881532023334, "Product administration error ": 2.6489762917871937, "Respiratory arrest ": 7.860429297354565, "Second primary malignancy ": 3.2761814822481186, "Serotonin syndrome ": 3.847451254053208, "Suicide attempt ": 2.4339439790766195, "Toxic epidermal necrolysis ": 3.466140014766302, "Toxicity to various agents ": 3.802238221195037, "Tuberculosis ": 4.251922774232854, "Urinary incontinence ": 2.281109379589915, "Urinary tract infection bacterial ": 22.279676895935197, "Urine output decreased ": 3.824418318454219, "Vaccination site inflammation ": 2.5961379245385032, "Ventricular tachycardia ": 2.27077666268135}
\ No newline at end of file
+{"Accidental exposure to product": 5.489540689415383, "Adverse drug reaction": 3.734081652832816, "Adverse event": 3.0525515701274557, "Blood potassium decreased": 4.419237089920904, "Cardiac disorder": 2.1757967178613757, "Cataract": 3.676902182580594, "Constipation": 2.816880668151944, "Cytopenia": 4.037405475686255, "Death": 19.98665603141148, "Dehydration": 3.838116975576497, "Dementia": 2.2700589236002946, "Diarrhoea": 3.748667905027791, "Dry skin": 2.0652185055844936, "Fall": 2.5956628686062637, "Full blood count abnormal": 2.5888930296866453, "Full blood count decreased": 24.739155655112604, "Haemoglobin decreased": 2.0406625837343286, "Hospitalisation": 3.901504449895852, "Illness": 3.304630295936773, "Laboratory test abnormal": 11.40718050355891, "Muscle spasms": 2.0220090332138345, "Neuropathy peripheral": 18.208292957060376, "Off label use": 6.845518806544624, "Peripheral swelling": 3.234383834447606, "Plasma cell myeloma": 101.63486272063848, "Plasma cell myeloma recurrent": 99.10039417222528, "Platelet count decreased": 6.107446022842427, "Pneumonia": 5.135212221689135, "Product dose omission issue": 4.1203552947069815, "Product physical issue": 17.10124564727359, "Red blood cell count decreased": 2.693605988565964, "Renal disorder": 2.222992634350733, "Rib fracture": 3.5169239498910576, "Sepsis": 3.438566071639955, "Thrombosis": 2.08882954836856, "Upper respiratory tract infection": 2.1587438697775645, "Urinary tract infection": 2.4603594319233664, "White blood cell count decreased": 4.675813905010871}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/772.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/772.json
index 73680c4bfb5..fd702c764bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/772.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/772.json
@@ -1 +1 @@
-{"Blood glucose increased ": 10.042285367449557, "Diabetes mellitus inadequate control ": 38.6016981657808, "Diabetic ketoacidosis ": 12.350700832129338, "Exposure during pregnancy ": 4.833433619030855, "Hyperglycaemia ": 8.589314474132722, "Hypersensitivity ": 2.1337206904577357, "Hypoglycaemia ": 35.05767410149898, "Hypoglycaemic coma ": 165.189958337253, "Injection site pruritus ": 13.209800082830222, "Product dispensing error ": 39.40436118860804, "Product prescribing error ": 30.03727917918204, "Wrong product administered ": 83.92931315587076}
\ No newline at end of file
+{"Diarrhoea": 3.1437340560273848, "Vomiting": 2.9899331626615533}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/773.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/773.json
index 18d7d1d2652..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/773.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/773.json
@@ -1 +1 @@
-{"Acidosis ": 8.83169939629433, "Acute kidney injury ": 3.179576466412029, "Aphasia ": 4.743917001567636, "Autoimmune haemolytic anaemia ": 21.04589928996799, "Blood alkaline phosphatase increased ": 2.420845792026028, "Blood glucose decreased ": 2.889050155628556, "Blood glucose increased ": 2.9686170471008397, "Cholestasis ": 4.777065640616162, "Confusional state ": 3.2488741302965143, "Cutaneous vasculitis ": 8.597949967501325, "Diabetes mellitus inadequate control ": 16.849524671917386, "Drug interaction ": 2.55525570098869, "Dysarthria ": 3.80569693573888, "Eczema ": 5.52689235654284, "Eosinophilia ": 10.36986542694903, "Fall ": 2.034365480051007, "Gamma-glutamyltransferase increased ": 3.979566684953581, "Glycosylated haemoglobin increased ": 14.670057517393955, "Haemolytic anaemia ": 9.242107666145804, "Hepatic cytolysis ": 9.237396918335149, "Hepatic function abnormal ": 2.599755096988864, "Hepatitis ": 7.685350525024852, "Hepatitis cholestatic ": 7.083807913223398, "Hyperglycaemia ": 8.824095389220867, "Hyperkalaemia ": 5.269981239572672, "Hypoglycaemia ": 71.20607597732156, "Hypoglycaemic coma ": 124.80168898165324, "Hypoglycaemic seizure ": 45.6029861522495, "Hypoglycaemic unconsciousness ": 11.314966706868717, "Hyponatraemia ": 2.391470496955677, "Hypotension ": 2.094164582825625, "Jaundice ": 3.630345755487389, "Lactic acidosis ": 8.07938423012479, "Medication error ": 3.409721139114368, "Pancreatitis ": 2.964748557750767, "Pemphigoid ": 6.719764484327032, "Petechiae ": 2.9587553744478896, "Presyncope ": 2.031940858440355, "Pruritus ": 2.792910358094476, "Purpura ": 4.640106985486704, "Rash erythematous ": 2.9568521690083385, "Rash maculo-papular ": 3.134509368537787, "Rhabdomyolysis ": 3.2965332850104714, "Sopor ": 32.19721331352718, "Stevens-Johnson syndrome ": 2.516191609823207, "Thrombocytopenia ": 2.3743782240369784, "Toxic skin eruption ": 10.655662568813671, "Transaminases increased ": 3.1544603252198127, "Vascular purpura ": 32.95197618923166}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/774.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/774.json
index 267bcd40ce3..9711ae6c8d5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/774.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/774.json
@@ -1 +1 @@
-{"Accidental overdose ": 2.494252812938781, "Acetonaemia ": 31.514305333600795, "Anti-insulin antibody ": 286.48426815482804, "Anti-insulin antibody increased ": 110.0534227974708, "Anti-insulin antibody positive ": 125.76838697673116, "Blood glucose abnormal ": 39.75551157948605, "Blood glucose decreased ": 13.582459517961498, "Blood glucose fluctuation ": 56.583154744522645, "Blood glucose increased ": 62.05921934681912, "Blood ketone body ": 102.03766450034472, "Blood ketone body increased ": 89.67966453289556, "Blood ketone body present ": 1137.230427559035, "Cardiac operation ": 2.428297073316964, "Device breakage ": 81.84880374389091, "Device defective ": 34.47464415034286, "Device delivery system issue ": 42.2995124722648, "Device failure ": 82.04485592353478, "Device information output issue ": 239.37985664292012, "Device issue ": 30.279035304452343, "Device leakage ": 26.34448268205088, "Device malfunction ": 24.469430004656537, "Device mechanical issue ": 53.05827220231231, "Device occlusion ": 11.124646932472244, "Diabetes mellitus inadequate control ": 22.655253030706724, "Diabetic coma ": 4.533220415054642, "Diabetic foot ": 7.206626437068032, "Diabetic hyperglycaemic coma ": 39.17742908418572, "Diabetic ketoacidosis ": 46.18896473969487, "Diabetic ketoacidotic hyperglycaemic coma ": 39.75700705592475, "Diabetic ketosis ": 51.01979435211996, "Diabetic metabolic decompensation ": 9.84286379241238, "Diabetic retinopathy ": 9.194256592183038, "Drug effect less than expected ": 6.99623203876677, "Drug ineffective ": 3.5574089786754777, "Expired device used ": 49.00452325977799, "Expired product administered ": 3.846701851471861, "Exposure during pregnancy ": 3.0728010151267915, "Extra dose administered ": 11.69138153834254, "Foetal death ": 3.064037414838908, "Foetal distress syndrome ": 4.268012105755982, "Foetal exposure during pregnancy ": 3.1021002757896534, "Foetal growth restriction ": 4.8300422246110815, "Glycosylated haemoglobin abnormal ": 10.467937207372954, "Glycosylated haemoglobin increased ": 8.753577792273283, "Hunger ": 3.888563228743098, "Hyperglycaemia ": 83.28236223461992, "Hyperglycaemic unconsciousness ": 34.30867187137813, "Hyperinsulinaemic hypoglycaemia ": 23.778744399440228, "Hypoglycaemia ": 35.701191685792395, "Hypoglycaemia neonatal ": 13.321213904900002, "Hypoglycaemia unawareness ": 61.924815308449226, "Hypoglycaemic coma ": 40.732862030309256, "Hypoglycaemic encephalopathy ": 35.47961488533972, "Hypoglycaemic seizure ": 30.327697679174417, "Hypoglycaemic unconsciousness ": 49.929967348883615, "Incorrect dose administered ": 3.7889825724727375, "Incorrect dose administered by device ": 80.0238247811495, "Incorrect dose administered by product ": 31.850682159709184, "Increased insulin requirement ": 122.6253279074092, "Injection site atrophy ": 68.0236216001251, "Injection site hypersensitivity ": 4.817707583247729, "Injection site induration ": 3.4819774416232767, "Injection site mass ": 3.907895879742018, "Injection site rash ": 3.214744312999425, "Injection site urticaria ": 3.667253414712229, "Insulin resistance ": 17.916036704348898, "Intentional overdose ": 3.0614023831950026, "Ketoacidosis ": 8.495371101314843, "Ketosis ": 15.509255853264104, "Lack of injection site rotation ": 29.727780283293317, "Lipoatrophy ": 28.799145734600717, "Lipodystrophy acquired ": 5.226307908481054, "Lipohypertrophy ": 11.228253514148156, "Liquid product physical issue ": 388.0570938410197, "Maternal exposure during pregnancy ": 2.026240384028059, "Medication error ": 3.0556670585330057, "Multiple use of single-use product ": 16.014334764099562, "Needle issue ": 3.167046360729976, "Postprandial hypoglycaemia ": 97.1444273327776, "Pregnancy ": 2.5004122990402022, "Premature baby ": 4.686371898358253, "Premature delivery ": 2.7337242401064725, "Product administration error ": 2.517178850624717, "Product appearance confusion ": 16.30443179020188, "Product colour issue ": 8.00412571229209, "Product container issue ": 267.482597579064, "Product dispensing error ": 2.2251275871619924, "Product leakage ": 2060.6516560101154, "Product odour abnormal ": 19.287825546322203, "Product physical issue ": 278.4674230502161, "Product preparation error ": 8.550148413329795, "Product quality issue ": 43.95207905871248, "Product storage error ": 19.74191149168975, "Shock hypoglycaemic ": 11.988244192051583, "Suicide attempt ": 2.7650058371984563, "Suspected counterfeit product ": 3.388987555056583, "Suspected product quality issue ": 4.982845235291706, "Therapeutic product effect decreased ": 3.4513376420951225, "Therapeutic product effect delayed ": 27.396337164269465, "Therapeutic product effect variable ": 7.985875415631403, "Thrombin time prolonged ": 119.58125356646327, "Treatment noncompliance ": 2.207815894259765, "Urine ketone body present ": 32.5216082534543, "Wrong product administered ": 12.17244398819975, "Wrong technique in device usage process ": 5.895279498626724, "Wrong technique in product usage process ": 13.286197041593647}
\ No newline at end of file
+{"Drug interaction": 29.03088900401679}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/775.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/775.json
index 56305c965dc..f80e9f88115 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/775.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/775.json
@@ -1 +1 @@
-{"Abdominal sepsis ": 156.82509829685773, "Acute myocardial infarction ": 9.381868743964557, "Acute respiratory distress syndrome ": 10.83044446029163, "Anaphylactic reaction ": 2.590083057009188, "Anti factor VII antibody positive ": 4404.315166762161, "Antibody test positive ": 52.64303882449443, "Aortic thrombosis ": 74.40118164937415, "Arterial thrombosis ": 55.73916270229012, "Atrial thrombosis ": 54.12663883398388, "Brain death ": 25.612816933672114, "Brain injury ": 6.294831099992516, "Cardiac arrest ": 4.81014164974593, "Cardiac ventricular thrombosis ": 41.58012002717472, "Cardio-respiratory arrest ": 2.245226836950024, "Cerebral artery thrombosis ": 76.9067716569572, "Cerebral haemorrhage ": 4.722719853344857, "Cerebral infarction ": 24.097896312405474, "Cerebral ischaemia ": 49.06690376038344, "Cerebral thrombosis ": 21.579610112702134, "Cerebral venous sinus thrombosis ": 11.29863909780962, "Cerebrovascular accident ": 4.332363581482891, "Complication associated with device ": 31.177213612479523, "Concomitant disease progression ": 1018.7300870919788, "Coronary bypass thrombosis ": 1849.405728704364, "Death ": 8.805686075534213, "Deep vein thrombosis ": 20.65426123238788, "Device related thrombosis ": 73.5638634286628, "Dialysis ": 37.984717029716926, "Disseminated intravascular coagulation ": 46.49702813315186, "Drug ineffective ": 4.793173234629237, "Drug ineffective for unapproved indication ": 8.8789786987713, "Embolic stroke ": 27.60877028983399, "Embolism ": 33.62984673505934, "Embolism venous ": 26.891865923093462, "Exsanguination ": 960.9056807734388, "Factor VII inhibition ": 5911.667594544416, "Factor VIII inhibition ": 30.2553417773186, "Haemarthrosis ": 42.15458499907231, "Haematoma ": 6.861519736742956, "Haematuria ": 6.422925631293882, "Haemoperitoneum ": 31.41375430989804, "Haemorrhage ": 17.61263571739453, "Haemorrhage intracranial ": 18.8527181572159, "Haemothorax ": 27.37382281177756, "Hemiparesis ": 4.604553943933594, "Hepatic failure ": 3.888384459819625, "Hepatitis C ": 2.0385591352302272, "Hydrocephalus ": 12.765679601474098, "Hypovolaemic shock ": 27.48841974177974, "Intestinal ischaemia ": 38.035769153883145, "Intra-abdominal haemorrhage ": 26.907526308012773, "Intrapericardial thrombosis ": 1585.301723097751, "Ischaemia ": 16.876166078491035, "Ischaemic stroke ": 14.52672044546472, "Jugular vein thrombosis ": 71.44507794814716, "Knee arthroplasty ": 4.52778934410037, "Mesenteric vein thrombosis ": 48.53319812038328, "Multiple organ dysfunction syndrome ": 39.48044985677456, "Muscle haemorrhage ": 35.37199944726619, "Myocardial infarction ": 5.689921343228859, "Myocardial ischaemia ": 6.970902287729764, "Necrosis ": 15.89311978233603, "Off label use ": 5.0940904456049765, "Pelvic venous thrombosis ": 96.6587143580445, "Peripheral artery thrombosis ": 137.68330558704656, "Peripheral ischaemia ": 55.96816978497376, "Portal vein thrombosis ": 34.18865079316216, "Post procedural haemorrhage ": 18.917217920078333, "Postpartum haemorrhage ": 49.250872995599, "Pulmonary embolism ": 16.17265945187263, "Pulmonary haemorrhage ": 16.943045039242946, "Pulmonary oedema ": 2.615455282803346, "Renal cortical necrosis ": 426.38523158099525, "Respiratory distress ": 2.664804157544525, "Sepsis ": 7.082085622208874, "Septic shock ": 8.011561883013968, "Shock ": 4.882720249727275, "Shock haemorrhagic ": 48.33520035500083, "Subarachnoid haemorrhage ": 5.5505605038922665, "Subclavian vein thrombosis ": 109.26752282674882, "Therapeutic response decreased ": 42.53762691843345, "Therapy non-responder ": 2.6224624656119526, "Thrombosis ": 12.16081409048568, "Thrombosis in device ": 36.71735091326151, "Thrombotic stroke ": 202.00877410635283, "Vena cava thrombosis ": 169.02767191097865, "Venous thrombosis ": 28.67044132554181, "Venous thrombosis limb ": 26.47923832804478}
\ No newline at end of file
+{"Drug ineffective": 6.3377433703104575, "Pleural effusion": 18.998825150892745, "Therapy non-responder": 40.35757021236692}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/776.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/776.json
index ed397541c3e..f57792953a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/776.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/776.json
@@ -1 +1 @@
-{"Acquired apparent mineralocorticoid excess ": 2864.886879155343, "Acute kidney injury ": 2.3852890717477555, "Acute myeloid leukaemia ": 24.785084851839628, "Acute respiratory failure ": 4.208014704671731, "Adrenal insufficiency ": 3.9711009107998536, "Adverse event ": 22.59553898658379, "Aspartate aminotransferase increased ": 2.4028057381702985, "Aspergillus infection ": 30.32686296215917, "Bilirubin conjugated increased ": 20.31168938613883, "Blood alkaline phosphatase increased ": 3.31284119327257, "Blood bilirubin increased ": 3.69024215970927, "Blood potassium decreased ": 2.945177435864435, "Bone marrow transplant ": 41.72220930244511, "Brain oedema ": 3.990498097432586, "Bronchopulmonary aspergillosis ": 38.15860262220375, "Cardiac arrest ": 2.0398123914579114, "Cholestasis ": 14.473180428141289, "Clostridium difficile colitis ": 6.237991797570545, "Death ": 6.051921372326699, "Disseminated intravascular coagulation ": 3.526934410348404, "Drug eruption ": 2.432980672758028, "Drug interaction ": 4.8728660879750905, "Drug level below therapeutic ": 65.37934506990794, "Drug level decreased ": 27.332020931715466, "Drug level increased ": 10.15602281033183, "Drug-induced liver injury ": 11.350082414503678, "Electrocardiogram QT prolonged ": 12.799748002865092, "Febrile neutropenia ": 4.697960667887392, "Fungal infection ": 8.594273963669927, "Fusarium infection ": 83.96084495144952, "Gamma-glutamyltransferase increased ": 5.3613844045880565, "Gastrointestinal tube insertion ": 16.854719342134363, "Graft versus host disease ": 30.741090940429768, "Graft versus host disease in gastrointestinal tract ": 20.70373000431945, "Hallucination, visual ": 3.4786890835323323, "Hepatic cytolysis ": 16.68721068391925, "Hepatic enzyme increased ": 3.214384020088055, "Hepatic failure ": 3.2106361777137837, "Hepatic function abnormal ": 2.9074267306114456, "Hepatitis ": 2.826114714885663, "Hepatitis cholestatic ": 4.309402186794785, "Hepatotoxicity ": 9.44454040464298, "Hyperbilirubinaemia ": 12.02073830328612, "Hypertransaminasaemia ": 9.717181600805674, "Hypokalaemia ": 18.0082903154935, "Hypomagnesaemia ": 13.258917634714832, "Ileus ": 4.532827050205031, "Ileus paralytic ": 11.322323292353287, "Inappropriate schedule of product administration ": 2.6324839157921502, "Incorrect dose administered ": 5.624872202858161, "Incorrect product dosage form administered ": 121.41060628921166, "Incorrect route of product administration ": 3.450011556572698, "Infection ": 2.389487812297622, "Intestinal haemorrhage ": 13.06149933180976, "Jaundice ": 2.3434798526277407, "Leukaemia ": 21.38399227889401, "Leukaemia recurrent ": 24.593829632849364, "Liver function test increased ": 4.335560642673161, "Liver injury ": 5.327940108793181, "Malabsorption ": 10.608870916373665, "Mucormycosis ": 29.03308476274195, "Mucosal inflammation ": 2.6580712168914555, "Multiple organ dysfunction syndrome ": 2.4287226916008247, "Myelodysplastic syndrome ": 11.827850148551256, "Neuralgia ": 2.1974396879125173, "Neurotoxicity ": 6.764302951957865, "Neutropenia ": 2.096169743875733, "Neutropenic colitis ": 39.42474232419959, "Oedematous pancreatitis ": 80.13697504153676, "Pancytopenia ": 2.8009232853139765, "Pathogen resistance ": 5.083665961297556, "Pericardial effusion ": 2.384937464532678, "Pneumonia fungal ": 53.83966995819555, "Polyneuropathy ": 2.94554929983637, "Posterior reversible encephalopathy syndrome ": 6.140828521412818, "Potentiating drug interaction ": 12.11631913255806, "Prescribed overdose ": 4.341061389787439, "Primary adrenal insufficiency ": 124.51802954776834, "Product administered to patient of inappropriate age ": 9.057095832837096, "Product administration error ": 2.076004331048994, "Product prescribing error ": 9.248677374246196, "Product quality issue ": 2.685614224675173, "Product use in unapproved indication ": 4.556961834277461, "Product use issue ": 4.942068034371759, "Pseudoaldosteronism ": 411.6086505306429, "Pulmonary arterial hypertension ": 5.0337067460999245, "Pulmonary mass ": 4.456824297816995, "Rash maculo-papular ": 5.526468746979514, "Respiratory failure ": 2.230110438408157, "Rhabdomyolysis ": 2.626002675550662, "Sepsis ": 2.869312625301245, "Septic shock ": 4.28646637287122, "Surgery ": 2.16621510444783, "Systemic candida ": 33.47062391872174, "Systemic mycosis ": 60.837678206015845, "Therapeutic product ineffective ": 44.95315197238797, "Torsade de pointes ": 5.670727954872186, "Toxic skin eruption ": 5.3662063533103606, "Transaminases increased ": 2.3729938327800726, "Transplant ": 31.952443550984203, "Ventricular fibrillation ": 3.404301669823714, "Ventricular tachycardia ": 2.1577874157700605}
\ No newline at end of file
+{"Back pain": 6.015607359172312, "Bone pain": 40.68673118342683, "Drug ineffective": 2.8851385123711863, "Erythema": 4.6228901260565, "Febrile neutropenia": 6.590292384945143, "Neutropenia": 8.225858121857128, "Neutrophil count decreased": 10.95394276252234, "Pruritus": 2.74114410726709, "Therapy non-responder": 16.09817836440411, "Thrombocytopenia": 2.719744750287502, "Urticaria": 2.451895991508003}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/777.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/777.json
index 0b12cbb6fdb..56b8046364f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/777.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/777.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 3.087925402979168, "Acute leukaemia ": 11.176246968425763, "Acute myeloid leukaemia ": 17.345181884714155, "Acute myocardial infarction ": 3.7500235484250375, "Acute respiratory distress syndrome ": 2.977634247453474, "Acute respiratory failure ": 3.064471804300969, "Antibody test positive ": 20.66925026279972, "Aplastic anaemia ": 8.982684556704914, "Atelectasis ": 4.484617580991387, "Bacteraemia ": 3.389601660596536, "Biopsy bone marrow abnormal ": 626.922686658039, "Blast cell count increased ": 18.90257243573125, "Blood blister ": 15.059613537086902, "Bone marrow disorder ": 34.29551846940135, "Bone marrow failure ": 2.7653250396083124, "Cardiac failure congestive ": 3.0831628535593083, "Cardiac operation ": 3.292851521059287, "Cerebrovascular accident ": 2.218281948621779, "Chronic lymphocytic leukaemia ": 65.19615218052027, "Chronic myeloid leukaemia ": 7.391607919050483, "Chronic myelomonocytic leukaemia ": 94.18328327149382, "Chronic obstructive pulmonary disease ": 2.272520148987166, "Colon cancer ": 2.439802816128359, "Contusion ": 4.031802295293554, "Death ": 4.6084819653539855, "Deep vein thrombosis ": 6.6693390811726845, "Drug ineffective ": 4.708756064623125, "Ecchymosis ": 10.495947772092176, "Embolic stroke ": 5.517723805720633, "Embolism ": 19.10742456150288, "End stage renal disease ": 2.08161450725286, "Epistaxis ": 3.814291566420444, "Evans syndrome ": 88.72577118324857, "Failure to thrive ": 8.235299558146043, "Fibrosis ": 8.887544667574392, "Gastrointestinal haemorrhage ": 3.2976614403712707, "Gingival bleeding ": 5.727288356321504, "Haematological malignancy ": 89.06962410391, "Haemolysis ": 2.371862999466807, "Haemolytic anaemia ": 3.15142464965738, "Haemorrhage ": 5.925795297407532, "Haemorrhage intracranial ": 6.177479515365452, "Haemorrhagic diathesis ": 6.169661660172122, "Hepatic cirrhosis ": 5.375563519809614, "Hospitalisation ": 10.694966266236486, "Hypervolaemia ": 2.727583185079108, "Immune thrombocytopenia ": 19.30216738565376, "Immunosuppression ": 5.897940324943267, "Increased tendency to bruise ": 7.163117585870479, "Iron deficiency anaemia ": 2.9437158384846045, "Ischaemic stroke ": 2.3602931562124865, "Leukaemia ": 5.240278610971806, "Leukocytosis ": 10.095916600891856, "Loss of therapeutic response ": 11.631305082728998, "Lung cancer metastatic ": 11.467003295264314, "Lung infiltration ": 2.1311599455599515, "Lung neoplasm malignant ": 3.222570331459524, "Lymphoma ": 11.45106539331197, "Malnutrition ": 6.010383354639162, "Marrow hyperplasia ": 37.25801268760016, "Megakaryocytes increased ": 116.04096468830942, "Metastases to central nervous system ": 2.2319180727125825, "Mouth haemorrhage ": 14.5808009714183, "Mucosal haemorrhage ": 32.88185867075616, "Multimorbidity ": 70.97405534452291, "Myelodysplastic syndrome ": 45.83262020298119, "Myelofibrosis ": 172.97106796132394, "Myeloproliferative neoplasm ": 33.1015936978901, "Neutrophilia ": 7.265477843620469, "Non-Hodgkin's lymphoma ": 15.2589506438617, "Normochromic normocytic anaemia ": 6.497698601778965, "Oedema peripheral ": 2.073364648811989, "Ovarian cancer ": 5.093898146353857, "Pancytopenia ": 2.8743240396404888, "Petechiae ": 13.91609803673088, "Plasma cell myeloma ": 3.043583585862543, "Platelet count abnormal ": 460.8840840660201, "Platelet count decreased ": 23.80966116232555, "Platelet count increased ": 57.43959250496793, "Platelet disorder ": 28.565846645997446, "Pleural effusion ": 4.769703720102466, "Pneumonia ": 2.0303820629317406, "Portal hypertension ": 6.3400550753037965, "Portal vein thrombosis ": 9.267955716133097, "Post procedural complication ": 3.8925661779645377, "Pulmonary embolism ": 3.889300773120176, "Pulmonary haemorrhage ": 4.167726210467282, "Purpura ": 4.146955793793382, "Refusal of treatment by patient ": 28.88365778285081, "Respiratory failure ": 3.5677381090846887, "Sepsis ": 4.192723972528166, "Skin haemorrhage ": 5.2744455099479, "Splenectomy ": 311.73620254576184, "Splenomegaly ": 8.178013985838023, "Subdural haematoma ": 3.1179691023027325, "Surgery ": 3.460631573381158, "Therapeutic product effect decreased ": 6.578052971960744, "Therapeutic response decreased ": 83.09796888638398, "Therapy non-responder ": 7.145311460460656, "Thrombocytopenia ": 7.866046156448394, "Thrombocytosis ": 43.84949571751786, "Thrombosis ": 4.1292473083755565, "Treatment noncompliance ": 2.0192496068647863, "Unevaluable event ": 3.153059293777298, "Venous thrombosis ": 3.3918256674430105, "Viral infection ": 2.617038220945177, "White blood cell count increased ": 4.054179709338397}
\ No newline at end of file
+{"Autoimmune colitis": 276.2340299667652, "Autoimmune hepatitis": 17.700799856520298, "Colitis": 19.129692055515655, "Cytokine release syndrome": 9.828316228198046, "Diarrhoea": 2.185987500949361, "Disease progression": 2.9098079279125404, "Disseminated intravascular coagulation": 6.398233506509516, "Febrile neutropenia": 4.417913398160295, "General physical health deterioration": 3.617301823443557, "Hepatitis": 8.036037532095412, "Hyperthyroidism": 13.733024371330457, "Hypophysitis": 43.702356243315045, "Hypothyroidism": 9.008905793415217, "Hypoxia": 6.651576087221208, "Immune effector cell-associated neurotoxicity syndrome": 29.17319603670109, "Immune-mediated enterocolitis": 19.21659460783954, "Immune-mediated lung disease": 43.140781727226496, "Intentional product use issue": 15.870568551441863, "Interstitial lung disease": 6.7850585540992805, "Liver disorder": 3.7695818139304142, "Malignant neoplasm progression": 16.716958692412284, "Myelosuppression": 2.8073429482323893, "Myocarditis": 2.253765564560521, "Neuropathy peripheral": 4.780193557916763, "Neutrophil count decreased": 3.901483877629969, "Off label use": 2.49951404056358, "Pemphigoid": 8.214773220965009, "Platelet count decreased": 2.2376397529940717, "Pneumonia aspiration": 8.791811334014902, "Pneumonitis": 12.589674995197182, "Rash maculo-papular": 3.2056945670083703, "Thyroiditis": 22.155168635566707, "Transaminases increased": 3.3959035460486606, "Tubulointerstitial nephritis": 12.246605952736468, "White blood cell count decreased": 2.8546894329722026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/778.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/778.json
index 7bdf72affc7..27087fa400f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/778.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/778.json
@@ -1 +1 @@
-{"Vomiting ": 2.7733782287109467}
\ No newline at end of file
+{"Acute kidney injury": 12.206761895527944, "Atrial fibrillation": 6.665139202308041, "Hyperkalaemia": 11.221860241022112, "Hypotension": 9.32037220242935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/779.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/779.json
index 1f6cfa9d9ec..24714010a11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/779.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/779.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 6.88818400140666, "Aspartate aminotransferase increased ": 6.011683966705379, "Blood bilirubin increased ": 4.915613131664772, "Decreased appetite ": 2.189914623239177, "Hepatic function abnormal ": 6.281596871720396, "Hepatotoxicity ": 8.578679038591302, "Hormone-refractory prostate cancer ": 1055.486014613139, "Hot flush ": 4.145841274519624, "Malignant neoplasm progression ": 2.028595623473497, "Metastases to bone ": 28.788696981352857, "Neuropathy peripheral ": 2.9011351303214377, "Neutropenia ": 2.1250871955420654, "Neutrophil count decreased ": 5.86333247139274, "Off label use ": 4.3126719736326615, "Prostate cancer ": 43.88348774865375, "Prostatic specific antigen increased ": 166.0449101665958, "Rash ": 2.327269795723505, "Renal impairment ": 4.450927974475155}
\ No newline at end of file
+{"Crying": 35.76743583956051, "Pyrexia": 2.3063790542938856, "Rash": 2.4208544733706376}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/78.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/78.json
index 4e6e1383717..b4e855d428e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/78.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/78.json
@@ -1 +1 @@
-{"Completed suicide ": 94.20060036223455, "Toxicity to various agents ": 30.657637203995407}
\ No newline at end of file
+{"Acute kidney injury": 9.00567855366251, "Completed suicide": 35.925444641320624, "Drug ineffective": 2.2254242727149185, "Toxicity to various agents": 16.31705215644659}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/780.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/780.json
index e4eeca6881e..9127e27559f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/780.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/780.json
@@ -1 +1 @@
-{"Accidental exposure to product ": 3.5218586355888664, "Addison's disease ": 54.51033010058474, "Adverse drug reaction ": 3.607589687386088, "Antineutrophil cytoplasmic antibody ": 90.51391258008884, "Aphonia ": 2.2660679947393056, "Appetite disorder ": 2.5267073739393293, "Areflexia ": 2.7301664594454587, "Asphyxia ": 2.0587769838947976, "Aspiration ": 4.9843300911235415, "Asthma ": 29.15553155286551, "Asthmatic crisis ": 56.63213649759543, "Atelectasis ": 7.488699292738349, "Blood calcium increased ": 3.115085452267677, "Blood immunoglobulin E increased ": 4.54511312955349, "Blood lactic acid increased ": 40.259823225568354, "Blood potassium decreased ": 14.982065620990562, "Blood test abnormal ": 5.777465402095108, "Breath sounds abnormal ": 73.47428160643537, "Bronchial hyperreactivity ": 6.511848256408243, "Bronchial obstruction ": 18.436061770516137, "Bronchial secretion retention ": 11.75302990976973, "Bronchial wall thickening ": 27.33815615126919, "Bronchiectasis ": 13.944320408380218, "Bronchitis ": 4.293013463825864, "Bronchopulmonary aspergillosis allergic ": 35.292782774382566, "Bronchospasm ": 3.5906078473650016, "Chest X-ray abnormal ": 65.1313711858788, "Chest discomfort ": 5.256251788860213, "Choking ": 2.7782184905837437, "Chronic obstructive pulmonary disease ": 2.74879855952992, "Chronic sinusitis ": 8.771773175649724, "Circumstance or information capable of leading to medication error ": 2.598652114433037, "Condition aggravated ": 2.546617939314827, "Coronavirus infection ": 7.874167899892764, "Coronavirus test positive ": 34.91366486644537, "Costochondritis ": 2.7969943388596783, "Cough ": 5.687454229874471, "Crepitations ": 5.7458121102828015, "Cushingoid ": 5.550538277420239, "Cystitis ": 7.1193810432333375, "Decreased activity ": 4.226112438147708, "Decreased immune responsiveness ": 2.020636795964992, "Depressive symptom ": 2.385547425297526, "Discouragement ": 6.936627179755137, "Disease recurrence ": 2.864808161385091, "Drug effective for unapproved indication ": 2.2245982795728616, "Dysphonia ": 2.078571297234622, "Dyspnoea ": 4.560843310605736, "Dyspnoea exertional ": 6.0232642095907, "Ear disorder ": 2.4052074984885774, "Ear pruritus ": 77.35007943592682, "Eczema ": 3.318838805740992, "Emergency care ": 7.68482735417072, "Emphysema ": 4.2438251962019455, "Endotracheal intubation ": 2.146490429448382, "Eosinophil count abnormal ": 47.422038003134645, "Eosinophil count decreased ": 10.040416379536142, "Eosinophil count increased ": 16.00585565035049, "Eosinophilia ": 9.331775714589345, "Eosinophilic granulomatosis with polyangiitis ": 10.801868831141098, "Exercise tolerance decreased ": 2.5743509484196205, "Exposure via skin contact ": 69.02797586140414, "Eye paraesthesia ": 34.26641955359657, "Eye pruritus ": 16.47889463962502, "Eye swelling ": 4.59107640911883, "Facial discomfort ": 5.504395214122872, "Fear of injection ": 16.948859976954825, "Flank pain ": 2.0012056515420373, "Forced expiratory volume decreased ": 10.266101818017672, "Forced expiratory volume increased ": 101.09095623438807, "Forced vital capacity decreased ": 33.55650450346649, "Full blood count abnormal ": 48.52047214251426, "Glaucoma ": 3.118923398213462, "Glucose tolerance impaired ": 3.803117986316304, "Goitre ": 3.524571283344288, "Haemophilus infection ": 25.818799675999053, "Haemoptysis ": 4.947750098599382, "Heart sounds ": 38.88681779653847, "Hospitalisation ": 4.702095792755077, "Hypereosinophilic syndrome ": 21.410970149285266, "Hypersensitivity pneumonitis ": 5.442411682079951, "Hypoventilation ": 5.318175688124239, "Ill-defined disorder ": 2.1149261151146166, "Illness ": 2.0996141618069, "Immune system disorder ": 4.320347479083358, "Impaired quality of life ": 2.7138071737065705, "Inappropriate schedule of product administration ": 3.2746659512288554, "Increased bronchial secretion ": 2.8277202722080066, "Increased upper airway secretion ": 5.665344135254439, "Increased viscosity of upper respiratory secretion ": 6.840253189711001, "Infection ": 2.156178613533952, "Injection site discomfort ": 3.307850509837743, "Kidney infection ": 10.887913238337584, "Lacrimation increased ": 10.850182332376242, "Laryngeal disorder ": 12.058114262630909, "Loss of personal independence in daily activities ": 21.02383876665718, "Lower respiratory tract infection ": 3.50551682711488, "Lung consolidation ": 3.354337926867295, "Lung disorder ": 3.466649002546725, "Lung hernia ": 425.78393148472776, "Lung opacity ": 4.2026060558520255, "Mean cell volume decreased ": 6.057295339447124, "Middle insomnia ": 6.172075998563005, "Multiple allergies ": 10.54796757817624, "Mycobacterial infection ": 5.738034805515741, "Mycobacterium avium complex infection ": 5.361211638852794, "Nasal congestion ": 11.98190999379069, "Nasal disorder ": 15.878804052461458, "Nasal obstruction ": 2.991981302186584, "Nasal oedema ": 6.445652306026791, "Nasal polyps ": 86.50490277073048, "Nasal septum deviation ": 12.105649200767076, "Nasopharyngitis ": 2.940658080063855, "Night sweats ": 3.4829862373181504, "Nocturnal dyspnoea ": 5.38451150271531, "Obstructive airways disorder ": 28.894712606831565, "Ocular discomfort ": 4.527092618176862, "Ocular hyperaemia ": 2.01306028874568, "Oesophageal disorder ": 8.343097745566656, "Oral candidiasis ": 2.952608828328524, "Oral disorder ": 2.769775191093403, "Orthopnoea ": 2.153137628093142, "Otitis media ": 2.0306372571671405, "Otitis media chronic ": 12.192410014874737, "Oxygen saturation abnormal ": 3.531892536643995, "Oxygen saturation decreased ": 3.247376428256293, "Paranasal sinus discomfort ": 14.623653732306344, "Peak expiratory flow rate decreased ": 27.090908040473565, "Personal relationship issue ": 38.69229326411551, "Pharyngeal erythema ": 4.993417676228683, "Pharyngitis ": 3.3772614685498428, "Platelet count increased ": 21.700830133042984, "Pleuritic pain ": 3.8535175399403543, "Pneumonia ": 2.5859808152975696, "Pneumonia bacterial ": 2.457264386405713, "Polyp ": 3.764454420152322, "Product availability issue ": 9.039400450353344, "Product complaint ": 3.6156508368937774, "Product dose omission issue ": 7.250737010273553, "Product supply issue ": 2.46385016218792, "Productive cough ": 20.470575809479367, "Prolonged expiration ": 34.643651327455025, "Psychiatric symptom ": 5.279707138902394, "Pulmonary congestion ": 5.169707211856276, "Pulmonary function test abnormal ": 119.7356182793479, "Pulmonary function test decreased ": 5.468197097036077, "Pulmonary mass ": 6.692055826789549, "Quality of life decreased ": 7.694663577878702, "Quarantine ": 86.09840673239793, "Radius fracture ": 4.715258109487136, "Rales ": 2.9297755110967154, "Rash erythematous ": 2.306004017275608, "Respiration abnormal ": 3.466113310119357, "Respiratory disorder ": 2.870849392494544, "Respiratory symptom ": 12.58699667424182, "Respiratory tract congestion ": 2.7244459686056373, "Respiratory tract infection ": 6.246309394523245, "Respiratory tract inflammation ": 17.555974229529102, "Restrictive pulmonary disease ": 14.675793833963285, "Reversible airways obstruction ": 13.911099665157383, "Rhinitis ": 4.082721937641772, "Rhinitis allergic ": 33.946734373763285, "Rhinorrhoea ": 7.345957782910604, "Rhonchi ": 8.904008941358247, "Scratch ": 5.729787806531688, "Seasonal allergy ": 12.068956122152686, "Secretion discharge ": 11.021208206452304, "Sense of oppression ": 5.056920313384757, "Sensitivity to weather change ": 4.195474716363843, "Sinonasal obstruction ": 34.29703659789128, "Sinus congestion ": 4.600022501682807, "Sinus disorder ": 2.560227120934633, "Sinus operation ": 8.964327499965702, "Sinusitis ": 5.587272853487301, "Skin fragility ": 16.48256749082065, "Skin laceration ": 2.0639544237429783, "Sleep disorder ": 2.593641060892796, "Sleep disorder due to a general medical condition ": 65.7299016530361, "Sneezing ": 16.031872127516685, "Social problem ": 16.87482700352584, "Spirometry abnormal ": 14.517285159092827, "Sputum abnormal ": 8.203618624413462, "Sputum discoloured ": 26.611245096240008, "Sputum purulent ": 16.456441624276096, "Sputum retention ": 21.661509990296125, "Surgery ": 2.311737178570053, "Symptom recurrence ": 4.96630252462112, "Therapeutic product effect incomplete ": 24.457094261444837, "Therapeutic response decreased ": 3.2429499302590523, "Therapy cessation ": 4.22584739676654, "Therapy interrupted ": 11.651533274925027, "Total lung capacity increased ": 12.582571534263272, "Tracheomalacia ": 17.997598113826598, "Tumour excision ": 12.919994594572508, "Upper respiratory tract congestion ": 6.57909633302121, "Upper respiratory tract infection ": 3.2238681238271245, "Upper-airway cough syndrome ": 64.30722268327983, "Urinary tract disorder ": 4.849096109410918, "Use of accessory respiratory muscles ": 38.43816974395397, "Vasculitis ": 13.480226469708178, "Viral infection ": 2.2828609024379247, "Vital capacity decreased ": 37.23038751428189, "Vocal cord dysfunction ": 10.766900999354563, "Vulvovaginal candidiasis ": 2.5850782775963808, "Wheezing ": 37.915359059490925, "Wrong technique in device usage process ": 7.756983701620193}
\ No newline at end of file
+{"Abortion spontaneous": 7.254318368077092, "Acute kidney injury": 5.211057898454889, "Adrenal insufficiency": 12.192195844638164, "Adverse event": 2.237508494936895, "Atrioventricular septal defect": 156.6128739519058, "Blood bilirubin increased": 9.56020195014718, "Blood creatine phosphokinase increased": 2.002202934435132, "Blood creatinine increased": 2.241142161003636, "Blood phosphorus decreased": 24.19163771582701, "Blood triglycerides increased": 3.241793039219291, "Caesarean section": 37.7469176081207, "Calculus urinary": 112.9198028176019, "Cell death": 34.658507580573975, "Cervical incompetence": 116.0334952499294, "Cholecystitis": 6.794073087952374, "Cholelithiasis": 9.640760788165757, "Cholestasis": 8.065466469323013, "Congenital bowing of long bones": 532.2562342398328, "Conjunctivitis": 2.0567808723047305, "Coronary artery occlusion": 4.184810950196142, "Cortisol decreased": 34.022475760079764, "Cushing's syndrome": 147.495289442233, "Cushingoid": 70.86810849352483, "Drug interaction": 7.566770834400439, "Drug level decreased": 5.582330660875571, "Drug level increased": 2.8310270506297863, "Drug reaction with eosinophilia and systemic symptoms": 5.0787652794900575, "Drug withdrawal syndrome neonatal": 4.830257194988777, "Dyslipidaemia": 22.02834438013721, "End stage renal disease": 2.6632980671724806, "Eosinophilia": 2.248148411607312, "Exposure during pregnancy": 6.037017700391125, "Eye disorder": 2.056079777300712, "Eyelid oedema": 4.209716842282538, "Fanconi syndrome": 65.88646132650825, "Fanconi syndrome acquired": 13.237790094603763, "Foetal death": 9.983281402854429, "Foetal exposure during pregnancy": 10.133152246833808, "Foetal growth restriction": 11.290556341965608, "Gestational diabetes": 28.894697793690543, "Glycosuria": 13.658677211931511, "Gynaecomastia": 3.833056649095538, "HIV infection": 27.34268683994153, "Haemolytic anaemia": 2.356238692080797, "Heart disease congenital": 22.051945591775198, "Hepatic cytolysis": 17.42151593690474, "Hepatic enzyme increased": 3.0386557845788955, "Hepatic steatosis": 5.292626917247405, "Hepatitis": 6.5386685202581765, "Hepatitis C": 2.3846614160916837, "Hepatotoxicity": 2.034388551964605, "Heterotaxia": 182.35772313239215, "Hydronephrosis": 19.56728830786064, "Hyperbilirubinaemia": 42.8540899561524, "Hypercapnia": 12.482923692416897, "Hypercholesterolaemia": 3.832174146612736, "Hypophosphataemia": 9.305293571570456, "Immune reconstitution inflammatory syndrome": 36.19482630371997, "Jaundice": 17.575446734860776, "Lactic acidosis": 2.1900375161912287, "Lipodystrophy acquired": 51.442515404716, "Lipohypertrophy": 60.87722005330464, "Live birth": 25.246827942120824, "Low birth weight baby": 3.490716487831572, "Lymphoma": 7.656605140753281, "Maternal exposure during pregnancy": 6.9877197980120105, "Metabolic acidosis": 2.035549662981824, "Mycobacterium avium complex infection": 13.744392662934828, "Myoglobin blood increased": 19.64221659720473, "Nephrolithiasis": 24.019914985710788, "Nephropathy toxic": 5.664561806643916, "Neuropathy peripheral": 2.114748151106037, "Normal newborn": 16.84186026990361, "Ocular icterus": 41.01902061840364, "Oedema": 2.0137407408963885, "Oral candidiasis": 3.1838893230475063, "Osteonecrosis": 2.3158143652694068, "Osteoporosis": 6.157647300067522, "Pancreatitis": 3.62235554795027, "Pancreatitis acute": 2.147938191645139, "Pancreatitis necrotising": 14.842834958997877, "Patent ductus arteriosus": 14.95502870289387, "Peripheral motor neuropathy": 36.550546887176736, "Peripheral sensory neuropathy": 7.426022793299137, "Polyneuropathy": 5.739199544723217, "Pregnancy": 19.068601939595894, "Pregnancy on contraceptive": 58.381615201498406, "Premature baby": 7.138323483931827, "Premature delivery": 9.566251248974568, "Premature labour": 18.05163915933248, "Premature rupture of membranes": 36.794002436428336, "Proteinuria": 7.953206706559948, "Rash macular": 2.1732448113742127, "Rash maculo-papular": 6.381747973221551, "Renal colic": 126.2362430253976, "Renal failure": 2.4082603796219657, "Renal tubular acidosis": 32.84003602602806, "Renal tubular disorder": 79.18725397218712, "Renal tubular necrosis": 6.1356269078419645, "Rhabdomyolysis": 3.186967632131719, "Rib fracture": 2.2766374056063348, "Spinal compression fracture": 8.421295783284583, "Stillbirth": 18.583614530309685, "Toxic skin eruption": 6.115183930949762, "Transaminases increased": 4.016202346785162, "Tubulointerstitial nephritis": 4.546324602029553, "Type 1 diabetes mellitus": 3.2835210247272197, "Uveitis": 7.044802104637939, "Ventricular fibrillation": 2.601898624979444, "Ventricular septal defect": 16.849989176550306, "Viral load increased": 18.752262737242443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/781.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/781.json
index d9415f9670f..0ac724d05ea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/781.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/781.json
@@ -1 +1 @@
-{"Vomiting ": 2.348133439257855}
\ No newline at end of file
+{"Adverse event": 3.590686376299836, "Angina unstable": 4.239119553640717, "Apnoea": 2.2698479644444087, "Atelectasis": 3.1221692277212894, "Autism spectrum disorder": 14.287018105182112, "Bacterial infection": 2.682976584492553, "Blood potassium increased": 2.2236532236778337, "Body temperature decreased": 3.2569288712147344, "Bundle branch block left": 7.8619749980933635, "Candida infection": 2.76320646320378, "Cardiac arrest": 4.020238732148068, "Cardio-respiratory arrest": 5.563850512307703, "Clostridium difficile colitis": 6.956412937382509, "Completed suicide": 14.45282963815395, "Crying": 4.116362532232704, "Cyanosis": 4.384247631892458, "Cytomegalovirus infection": 3.03590129454706, "Deafness neurosensory": 12.530174202446329, "Dehydration": 2.3496476898371137, "Dermatitis contact": 4.870256629086287, "Drug abuse": 8.004700452066203, "Drug interaction": 2.227006661370445, "Drug-induced liver injury": 2.1594961549809057, "Dysstasia": 2.231609408564929, "Encephalopathy": 2.511557103640587, "Eosinophil count increased": 2.407488415386257, "Febrile convulsion": 4.225170179279928, "Febrile neutropenia": 2.598327012138187, "Haemolytic anaemia": 2.4442927886467456, "Hepatic artery stenosis": 316.24411147327004, "Hepatic function abnormal": 2.731961783495609, "Herpes zoster": 2.548771515691624, "Hyperlipidaemia": 3.158938388842871, "Hypotonia": 4.338500861353692, "Hypotonic-hyporesponsive episode": 20.812459476653828, "Micturition urgency": 3.395840337597743, "Nervous system disorder": 4.132229480147723, "Ophthalmic herpes zoster": 5.990997569429214, "Overdose": 5.136330255025773, "Pallor": 3.716890169333408, "Poisoning": 3.0863450055831905, "Post herpetic neuralgia": 9.798881532023334, "Product administration error": 2.648768608787486, "Respiratory arrest": 7.860429297354565, "Second primary malignancy": 3.2761814822481186, "Serotonin syndrome": 3.847451254053208, "Suicide attempt": 2.4339439790766195, "Toxic epidermal necrolysis": 3.466140014766302, "Toxicity to various agents": 3.802238221195037, "Tuberculosis": 4.251922774232854, "Urinary incontinence": 2.281109379589915, "Urinary tract infection bacterial": 22.279676895935197, "Urine output decreased": 3.824418318454219, "Vaccination site inflammation": 2.5961379245385032, "Ventricular tachycardia": 2.27077666268135}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/782.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/782.json
index c56642c69ee..d9d2194e383 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/782.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/782.json
@@ -1 +1 @@
-{"Myalgia ": 4.250344691869928}
\ No newline at end of file
+{"Blood glucose increased": 10.042285367449557, "Diabetes mellitus inadequate control": 38.6016981657808, "Diabetic ketoacidosis": 12.350700832129338, "Exposure during pregnancy": 4.833433619030855, "Hyperglycaemia": 8.589314474132722, "Hypersensitivity": 2.1337206904577357, "Hypoglycaemia": 35.05648956645474, "Hypoglycaemic coma": 165.189958337253, "Injection site pruritus": 13.209800082830222, "Product dispensing error": 39.40436118860804, "Product prescribing error": 30.03727917918204, "Wrong product administered": 83.92931315587076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/783.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/783.json
index ec88c91ac4b..3c8b10bf220 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/783.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/783.json
@@ -1 +1 @@
-{"Epiphysiolysis ": 882.160968263104, "Intracranial pressure increased ": 66.21940442186816, "Meningioma ": 137.41681124373372, "Pneumonia ": 2.8336723434818083, "Scoliosis ": 165.5105509865673, "Seizure ": 2.878030355072476}
\ No newline at end of file
+{"Acidosis": 8.83169939629433, "Acute kidney injury": 3.179576466412029, "Aphasia": 4.743210234793339, "Autoimmune haemolytic anaemia": 21.04589928996799, "Blood alkaline phosphatase increased": 2.420845792026028, "Blood glucose decreased": 2.889050155628556, "Blood glucose increased": 2.9686170471008397, "Cholestasis": 4.777065640616162, "Confusional state": 3.2488741302965143, "Cutaneous vasculitis": 8.597949967501325, "Diabetes mellitus inadequate control": 16.849524671917386, "Drug interaction": 2.55525570098869, "Dysarthria": 3.80569693573888, "Eczema": 5.52689235654284, "Eosinophilia": 10.36986542694903, "Fall": 2.034313317703444, "Gamma-glutamyltransferase increased": 3.979566684953581, "Glycosylated haemoglobin increased": 14.670057517393955, "Haemolytic anaemia": 9.242107666145804, "Hepatic cytolysis": 9.237396918335149, "Hepatic function abnormal": 2.599755096988864, "Hepatitis": 7.685350525024852, "Hepatitis cholestatic": 7.083807913223398, "Hyperglycaemia": 8.824095389220867, "Hyperkalaemia": 5.269254127357439, "Hypoglycaemia": 71.2036395853591, "Hypoglycaemic coma": 124.80168898165324, "Hypoglycaemic seizure": 45.6029861522495, "Hypoglycaemic unconsciousness": 11.314966706868717, "Hyponatraemia": 2.391470496955677, "Hypotension": 2.0941161564963693, "Jaundice": 3.630345755487389, "Lactic acidosis": 8.07938423012479, "Medication error": 3.409476430489664, "Pancreatitis": 2.964748557750767, "Pemphigoid": 6.719764484327032, "Petechiae": 2.9587553744478896, "Presyncope": 2.031940858440355, "Pruritus": 2.792876513496672, "Purpura": 4.640106985486704, "Rash erythematous": 2.9568521690083385, "Rash maculo-papular": 3.134509368537787, "Rhabdomyolysis": 3.2965332850104714, "Sopor": 32.19721331352718, "Stevens-Johnson syndrome": 2.516191609823207, "Thrombocytopenia": 2.3741547970151102, "Toxic skin eruption": 10.655662568813671, "Transaminases increased": 3.154267107364038, "Vascular purpura": 32.95197618923166}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/784.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/784.json
index 6cdbfbd9442..7892eea8723 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/784.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/784.json
@@ -1 +1 @@
-{"Injection site haematoma ": 67.45453114642442, "Injection site pain ": 7.479922708016208}
\ No newline at end of file
+{"Accidental overdose": 2.493627884325964, "Acetonaemia": 31.506410387441605, "Anti-insulin antibody": 286.4124909198226, "Anti-insulin antibody increased": 110.02584984028977, "Anti-insulin antibody positive": 125.73687280565656, "Blood glucose abnormal": 39.74554720338875, "Blood glucose decreased": 13.57905534041813, "Blood glucose fluctuation": 56.56897214049346, "Blood glucose increased": 62.043640586915735, "Blood ketone body": 102.01209985285946, "Blood ketone body increased": 89.65719519899147, "Blood ketone body present": 1136.9454779448106, "Cardiac operation": 2.4276887301309604, "Device breakage": 81.82829397220559, "Device defective": 34.46600647967335, "Device delivery system issue": 42.28891372938724, "Device failure": 82.02429363915127, "Device information output issue": 239.31987965208108, "Device issue": 30.271447190621178, "Device leakage": 26.337881743047948, "Device malfunction": 24.46329778380651, "Device mechanical issue": 53.044979115324686, "Device occlusion": 11.121859766794302, "Diabetes mellitus inadequate control": 22.64957451594024, "Diabetic coma": 4.532084741376102, "Diabetic foot": 7.204820993085825, "Diabetic hyperglycaemic coma": 39.16761393407517, "Diabetic ketoacidosis": 46.17738404370029, "Diabetic ketoacidotic hyperglycaemic coma": 39.74704716142779, "Diabetic ketosis": 51.00701204501106, "Diabetic metabolic decompensation": 9.840397894892666, "Diabetic retinopathy": 9.191953090472891, "Drug effect less than expected": 6.994479310933891, "Drug ineffective": 3.556490459837339, "Expired device used": 48.99224621572243, "Expired product administered": 3.8457380988723378, "Exposure during pregnancy": 3.0720309934309062, "Extra dose administered": 11.688452176624503, "Foetal death": 3.06326977563021, "Foetal distress syndrome": 4.266942877509874, "Foetal exposure during pregnancy": 3.101322919600807, "Foetal growth restriction": 4.828832119411672, "Glycosylated haemoglobin abnormal": 10.465314744157077, "Glycosylated haemoglobin increased": 8.751384351868246, "Hunger": 3.887589026100776, "Hyperglycaemia": 83.2614672861301, "Hyperglycaemic unconsciousness": 34.30007688463178, "Hyperinsulinaemic hypoglycaemia": 23.772787140978377, "Hypoglycaemia": 35.69097452180055, "Hypoglycaemia neonatal": 13.317876542258707, "Hypoglycaemia unawareness": 61.90930039064607, "Hypoglycaemic coma": 40.722653022288696, "Hypoglycaemic encephalopathy": 35.470725986630804, "Hypoglycaemic seizure": 30.32009886417246, "Hypoglycaemic unconsciousness": 49.91745438889177, "Incorrect dose administered": 3.7880331360591137, "Incorrect dose administered by device": 80.00377033005442, "Incorrect dose administered by product": 31.84270283817101, "Increased insulin requirement": 122.5946050837822, "Injection site atrophy": 68.00657879180505, "Injection site hypersensitivity": 4.816500628940478, "Injection site induration": 3.4811050536648627, "Injection site mass": 3.906916806360983, "Injection site rash": 3.2139389143208463, "Injection site urticaria": 3.666334666644536, "Insulin resistance": 17.911548066961483, "Intentional overdose": 3.060635228388274, "Ketoacidosis": 8.493242506327617, "Ketosis": 15.505370335122697, "Lack of injection site rotation": 29.72033282706073, "Lipoatrophy": 28.79193052304979, "Lipodystrophy acquired": 5.224998560588492, "Lipohypertrophy": 11.225440598911884, "Liquid product physical issue": 387.9598312321807, "Maternal exposure during pregnancy": 2.0257326603473813, "Medication error": 3.0546814197193, "Multiple use of single-use product": 16.01032268205924, "Needle issue": 3.1662529253667806, "Postprandial hypoglycaemia": 97.12008934623589, "Pregnancy": 2.499785876742554, "Premature baby": 4.68519764820968, "Premature delivery": 2.7330393442680494, "Product administration error": 2.5163504669673995, "Product appearance confusion": 16.300347206330887, "Product colour issue": 8.002120466800525, "Product container issue": 267.41556891083013, "Product dispensing error": 2.2245701272421683, "Product leakage": 2060.135082327455, "Product odour abnormal": 19.28299296137272, "Product physical issue": 278.3976139497674, "Product preparation error": 8.548006383130557, "Product quality issue": 43.941061065418765, "Product storage error": 19.73696409296459, "Shock hypoglycaemic": 11.985240820837026, "Suicide attempt": 2.764312973355479, "Suspected counterfeit product": 3.3881385451670125, "Suspected product quality issue": 4.9815969261720605, "Therapeutic product effect decreased": 3.4504728421063526, "Therapeutic product effect delayed": 27.38947306592321, "Therapeutic product effect variable": 7.983874734806173, "Thrombin time prolonged": 119.55129545834102, "Treatment noncompliance": 2.207262736819068, "Urine ketone body present": 32.51346036899803, "Wrong product administered": 12.169393862975722, "Wrong technique in device usage process": 5.8938025206347975, "Wrong technique in product usage process": 13.282866946254314}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/785.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/785.json
index 4c96fd326c6..b6acd10e4c4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/785.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/785.json
@@ -1 +1 @@
-{"Gamma-glutamyltransferase abnormal ": 1002.8322798423314, "Hepatic cirrhosis ": 52.45252841805807, "Product dose omission issue ": 6.862924498692259, "Pruritus ": 12.693377056655589}
\ No newline at end of file
+{"Abdominal sepsis": 156.82509829685773, "Acute myocardial infarction": 9.381868743964557, "Acute respiratory distress syndrome": 10.83044446029163, "Anaphylactic reaction": 2.590027992277582, "Anti factor VII antibody positive": 4404.315166762161, "Antibody test positive": 52.64303882449443, "Aortic thrombosis": 74.40118164937415, "Arterial thrombosis": 55.73916270229012, "Atrial thrombosis": 54.12663883398388, "Brain death": 25.612816933672114, "Brain injury": 6.294831099992516, "Cardiac arrest": 4.81014164974593, "Cardiac ventricular thrombosis": 41.58012002717472, "Cardio-respiratory arrest": 2.245226836950024, "Cerebral artery thrombosis": 76.9067716569572, "Cerebral haemorrhage": 4.722719853344857, "Cerebral infarction": 24.097896312405474, "Cerebral ischaemia": 49.06690376038344, "Cerebral thrombosis": 21.579610112702134, "Cerebral venous sinus thrombosis": 11.29863909780962, "Cerebrovascular accident": 4.33228544370561, "Complication associated with device": 31.177213612479523, "Concomitant disease progression": 1018.7300870919788, "Coronary bypass thrombosis": 1849.405728704364, "Death": 8.805686075534213, "Deep vein thrombosis": 20.65426123238788, "Device related thrombosis": 73.5638634286628, "Dialysis": 37.984717029716926, "Disseminated intravascular coagulation": 46.49702813315186, "Drug ineffective": 4.793137765536696, "Drug ineffective for unapproved indication": 8.8789786987713, "Embolic stroke": 27.60877028983399, "Embolism": 33.62984673505934, "Embolism venous": 26.891865923093462, "Exsanguination": 960.9056807734388, "Factor VII inhibition": 5911.667594544416, "Factor VIII inhibition": 30.2553417773186, "Haemarthrosis": 42.15458499907231, "Haematoma": 6.861519736742956, "Haematuria": 6.422925631293882, "Haemoperitoneum": 31.41375430989804, "Haemorrhage": 17.61263571739453, "Haemorrhage intracranial": 18.8527181572159, "Haemothorax": 27.37382281177756, "Hemiparesis": 4.603973416240186, "Hepatic failure": 3.888384459819625, "Hepatitis C": 2.0385591352302272, "Hydrocephalus": 12.765679601474098, "Hypovolaemic shock": 27.48841974177974, "Intestinal ischaemia": 38.035769153883145, "Intra-abdominal haemorrhage": 26.907526308012773, "Intrapericardial thrombosis": 1585.301723097751, "Ischaemia": 16.876166078491035, "Ischaemic stroke": 14.52672044546472, "Jugular vein thrombosis": 71.44507794814716, "Knee arthroplasty": 4.52778934410037, "Mesenteric vein thrombosis": 48.53319812038328, "Multiple organ dysfunction syndrome": 39.48044985677456, "Muscle haemorrhage": 35.37199944726619, "Myocardial infarction": 5.689921343228859, "Myocardial ischaemia": 6.970902287729764, "Necrosis": 15.89311978233603, "Off label use": 5.093889586142393, "Pelvic venous thrombosis": 96.6587143580445, "Peripheral artery thrombosis": 137.68330558704656, "Peripheral ischaemia": 55.96816978497376, "Portal vein thrombosis": 34.18865079316216, "Post procedural haemorrhage": 18.917217920078333, "Postpartum haemorrhage": 49.250872995599, "Pulmonary embolism": 16.17265945187263, "Pulmonary haemorrhage": 16.943045039242946, "Pulmonary oedema": 2.61511181731344, "Renal cortical necrosis": 426.38523158099525, "Respiratory distress": 2.664804157544525, "Sepsis": 7.082085622208874, "Septic shock": 8.011561883013968, "Shock": 4.882720249727275, "Shock haemorrhagic": 48.33520035500083, "Subarachnoid haemorrhage": 5.5505605038922665, "Subclavian vein thrombosis": 109.26752282674882, "Therapeutic response decreased": 42.53762691843345, "Therapy non-responder": 2.622233337489081, "Thrombosis": 12.16081409048568, "Thrombosis in device": 36.71735091326151, "Thrombotic stroke": 202.00877410635283, "Vena cava thrombosis": 169.02767191097865, "Venous thrombosis": 28.67044132554181, "Venous thrombosis limb": 26.47923832804478}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/786.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/786.json
index 12a54863d74..e3b00cfc3b1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/786.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/786.json
@@ -1 +1 @@
-{"Anaemia ": 3.04461810338983, "COVID-19 ": 3.1403432501461808, "COVID-19 pneumonia ": 35.547773488051604, "Cardiac disorder ": 3.986779381085997, "Chest discomfort ": 2.088978036511576, "Chronic lymphocytic leukaemia ": 32.88237100336362, "Cytokine release syndrome ": 4.613834293176742, "Cytomegalovirus chorioretinitis ": 38.14957595414204, "Cytomegalovirus infection ": 11.536225675524626, "Diffuse large B-cell lymphoma ": 16.381827453046256, "Disease progression ": 10.809035855524188, "Encephalopathy ": 3.36156516715479, "Febrile neutropenia ": 15.055158129567705, "Follicular lymphoma ": 363.2573263171178, "Haematotoxicity ": 12.510331163226136, "Hypogammaglobulinaemia ": 55.98488618870621, "Hypotension ": 2.11815358719954, "Infection ": 2.104484747780238, "Infusion related reaction ": 23.44582970320656, "Intentional product use issue ": 3.3335878198901407, "Lower respiratory tract infection ": 3.6044861194639073, "Lymphocyte count decreased ": 21.73966608870621, "Myelosuppression ": 9.993352816734342, "Neutropenia ": 17.50607540846971, "Neutropenic sepsis ": 26.11896152102213, "Neutrophil count decreased ": 7.683365102059168, "Off label use ": 4.034087234644688, "Oxygen saturation decreased ": 3.634564435890242, "Pancytopenia ": 2.248656063809772, "Platelet count decreased ": 5.313792504208246, "Pneumonia ": 5.5362657128565536, "Prescribed underdose ": 59.929557590833554, "Progressive multifocal leukoencephalopathy ": 24.636375546315737, "Septic shock ": 4.43836908477213, "Therapy partial responder ": 17.4979119892943, "Thrombocytopenia ": 8.375632949669955, "Tumour lysis syndrome ": 105.11442352676312, "Urinary tract infection ": 2.4348901757067654, "White blood cell count decreased ": 3.640182497062746}
\ No newline at end of file
+{"Acquired apparent mineralocorticoid excess": 2864.886879155343, "Acute kidney injury": 2.3852890717477555, "Acute myeloid leukaemia": 24.785084851839628, "Acute respiratory failure": 4.208014704671731, "Adrenal insufficiency": 3.9711009107998536, "Adverse event": 22.59553898658379, "Aspartate aminotransferase increased": 2.4028057381702985, "Aspergillus infection": 30.32686296215917, "Bilirubin conjugated increased": 20.31168938613883, "Blood alkaline phosphatase increased": 3.31284119327257, "Blood bilirubin increased": 3.69024215970927, "Blood potassium decreased": 2.945177435864435, "Bone marrow transplant": 41.72220930244511, "Brain oedema": 3.990498097432586, "Bronchopulmonary aspergillosis": 38.15860262220375, "Cardiac arrest": 2.0398123914579114, "Cholestasis": 14.473180428141289, "Clostridium difficile colitis": 6.237991797570545, "Death": 6.051921372326699, "Disseminated intravascular coagulation": 3.526934410348404, "Drug eruption": 2.432980672758028, "Drug interaction": 4.8728660879750905, "Drug level below therapeutic": 65.37934506990794, "Drug level decreased": 27.332020931715466, "Drug level increased": 10.15602281033183, "Drug-induced liver injury": 11.34938827918613, "Electrocardiogram QT prolonged": 12.799748002865092, "Febrile neutropenia": 4.697960667887392, "Fungal infection": 8.591884072473107, "Fusarium infection": 83.96084495144952, "Gamma-glutamyltransferase increased": 5.3613844045880565, "Gastrointestinal tube insertion": 16.854719342134363, "Graft versus host disease": 30.741090940429768, "Graft versus host disease in gastrointestinal tract": 20.70373000431945, "Hallucination, visual": 3.4786890835323323, "Hepatic cytolysis": 16.68721068391925, "Hepatic enzyme increased": 3.214384020088055, "Hepatic failure": 3.2106361777137837, "Hepatic function abnormal": 2.9074267306114456, "Hepatitis": 2.826114714885663, "Hepatitis cholestatic": 4.309402186794785, "Hepatotoxicity": 9.44454040464298, "Hyperbilirubinaemia": 12.02073830328612, "Hypertransaminasaemia": 9.717181600805674, "Hypokalaemia": 18.0082903154935, "Hypomagnesaemia": 13.258917634714832, "Ileus": 4.532827050205031, "Ileus paralytic": 11.322323292353287, "Inappropriate schedule of product administration": 2.6324839157921502, "Incorrect dose administered": 5.624872202858161, "Incorrect product dosage form administered": 121.41060628921166, "Incorrect route of product administration": 3.450011556572698, "Infection": 2.389487812297622, "Intestinal haemorrhage": 13.06149933180976, "Jaundice": 2.3434798526277407, "Leukaemia": 21.38399227889401, "Leukaemia recurrent": 24.593829632849364, "Liver function test increased": 4.335560642673161, "Liver injury": 5.327940108793181, "Malabsorption": 10.608870916373665, "Mucormycosis": 29.03308476274195, "Mucosal inflammation": 2.6580712168914555, "Multiple organ dysfunction syndrome": 2.4287226916008247, "Myelodysplastic syndrome": 11.827850148551256, "Neuralgia": 2.1974396879125173, "Neurotoxicity": 6.764302951957865, "Neutropenia": 2.0960795583070784, "Neutropenic colitis": 39.42474232419959, "Oedematous pancreatitis": 80.13697504153676, "Pancytopenia": 2.8009232853139765, "Pathogen resistance": 5.083665961297556, "Pericardial effusion": 2.384937464532678, "Pneumonia fungal": 53.83966995819555, "Polyneuropathy": 2.94554929983637, "Posterior reversible encephalopathy syndrome": 6.140828521412818, "Potentiating drug interaction": 12.11631913255806, "Prescribed overdose": 4.341061389787439, "Primary adrenal insufficiency": 124.51802954776834, "Product administered to patient of inappropriate age": 9.057095832837096, "Product administration error": 2.075841694296448, "Product prescribing error": 9.248677374246196, "Product quality issue": 2.685614224675173, "Product use in unapproved indication": 4.556819536706166, "Product use issue": 4.942068034371759, "Pseudoaldosteronism": 411.6086505306429, "Pulmonary arterial hypertension": 5.0337067460999245, "Pulmonary mass": 4.456824297816995, "Rash maculo-papular": 5.526468746979514, "Respiratory failure": 2.229926230001312, "Rhabdomyolysis": 2.626002675550662, "Sepsis": 2.869312625301245, "Septic shock": 4.28646637287122, "Surgery": 2.16621510444783, "Systemic candida": 33.47062391872174, "Systemic mycosis": 60.837678206015845, "Therapeutic product ineffective": 44.95315197238797, "Torsade de pointes": 5.670727954872186, "Toxic skin eruption": 5.3662063533103606, "Transaminases increased": 2.3728484579234226, "Transplant": 31.952443550984203, "Ventricular fibrillation": 3.404301669823714, "Ventricular tachycardia": 2.1577874157700605}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/787.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/787.json
index 379a3ad4c8f..1a77c7826ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/787.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/787.json
@@ -1 +1 @@
-{"Abdominal distension ": 4.050580729989552, "Alanine aminotransferase increased ": 3.1516736017069285, "Ascites ": 15.496527183662744, "Aspartate aminotransferase abnormal ": 79.22118340654633, "Aspartate aminotransferase increased ": 3.3833438359343453, "Blood albumin decreased ": 17.153475142848897, "Blood alkaline phosphatase abnormal ": 653.362880489703, "Blood alkaline phosphatase increased ": 26.190048824191013, "Blood bilirubin abnormal ": 88.7207386379766, "Blood bilirubin increased ": 30.106597693477987, "Child-Pugh-Turcotte score increased ": 872.0945336558773, "Cholelithiasis ": 3.0490047592324063, "Cholestasis ": 3.2684359384226678, "Chromaturia ": 5.281365597074943, "Constipation ": 2.6220960114471024, "Death ": 3.987673864796167, "Disease progression ": 2.9189590813590782, "Encephalopathy ": 2.0511740424404508, "Fall ": 2.2555612301838823, "Fluid retention ": 2.225937888796746, "Gamma-glutamyltransferase abnormal ": 239.1050901814988, "Gamma-glutamyltransferase increased ": 6.577725107121158, "Hepatic cirrhosis ": 44.77995960243233, "Hepatic encephalopathy ": 12.694429734823943, "Hepatic enzyme increased ": 2.8243513908082805, "Hepatic failure ": 27.502509529277027, "Hepatic fibrosis ": 79.48418554905066, "Hepatocellular carcinoma ": 2.697551802508707, "Hepatomegaly ": 5.031470260330458, "Hip fracture ": 4.097836635741317, "Hospitalisation ": 4.310960522177585, "Hyperbilirubinaemia ": 7.373711556774623, "Insurance issue ": 28.186777059639294, "Jaundice ": 11.290404913775614, "Laboratory test abnormal ": 11.790712629326505, "Liver disorder ": 2.315184593772416, "Liver function test increased ": 4.70692040957297, "Liver transplant ": 62.27696103920935, "Model for end stage liver disease score increased ": 3834.7455166239465, "Nervousness ": 2.500585402662928, "No adverse event ": 4.274842085440388, "Ocular icterus ": 16.88078745165721, "Oedema peripheral ": 2.6813740826178183, "Oesophageal varices haemorrhage ": 39.952015691301774, "Oral pain ": 3.645594118980828, "Portal hypertension ": 23.18355387462372, "Primary biliary cholangitis ": 131.2628631456531, "Product dose omission issue ": 4.929712691411372, "Product prescribing error ": 15.9354432815253, "Pruritus ": 13.14567507731868, "Skin haemorrhage ": 12.113433842089394, "Skin lesion ": 2.2192977404845484, "Splenomegaly ": 6.826762285652174, "Surgery ": 3.3667616356496044, "Therapy interrupted ": 57.92968715427239, "Transaminases increased ": 2.7240231985321826, "Treatment noncompliance ": 3.8220451455064, "Urinary tract infection ": 2.3210663771414404, "Varices oesophageal ": 24.7514758920342, "Viral infection ": 2.96029910183373, "Yellow skin ": 10.414216359918186}
\ No newline at end of file
+{"Acute coronary syndrome": 3.087925402979168, "Acute leukaemia": 11.176246968425763, "Acute myeloid leukaemia": 17.345181884714155, "Acute myocardial infarction": 3.7500235484250375, "Acute respiratory distress syndrome": 2.977634247453474, "Acute respiratory failure": 3.064471804300969, "Antibody test positive": 20.66925026279972, "Aplastic anaemia": 8.982684556704914, "Atelectasis": 4.484617580991387, "Bacteraemia": 3.389601660596536, "Biopsy bone marrow abnormal": 626.922686658039, "Blast cell count increased": 18.90257243573125, "Blood blister": 15.059613537086902, "Bone marrow disorder": 34.29551846940135, "Bone marrow failure": 2.7653250396083124, "Cardiac failure congestive": 3.082929196489029, "Cardiac operation": 3.292851521059287, "Cerebrovascular accident": 2.218241912673172, "Chronic lymphocytic leukaemia": 65.13886067572942, "Chronic myeloid leukaemia": 7.391607919050483, "Chronic myelomonocytic leukaemia": 94.18328327149382, "Chronic obstructive pulmonary disease": 2.272520148987166, "Colon cancer": 2.439802816128359, "Contusion": 4.031802295293554, "Death": 4.6084819653539855, "Deep vein thrombosis": 6.6693390811726845, "Drug ineffective": 4.708721136005309, "Ecchymosis": 10.495947772092176, "Embolic stroke": 5.517723805720633, "Embolism": 19.10742456150288, "End stage renal disease": 2.08161450725286, "Epistaxis": 3.814291566420444, "Evans syndrome": 88.72577118324857, "Failure to thrive": 8.235299558146043, "Fibrosis": 8.887544667574392, "Gastrointestinal haemorrhage": 3.2976614403712707, "Gingival bleeding": 5.727288356321504, "Haematological malignancy": 89.06962410391, "Haemolysis": 2.371862999466807, "Haemolytic anaemia": 3.15142464965738, "Haemorrhage": 5.925795297407532, "Haemorrhage intracranial": 6.177479515365452, "Haemorrhagic diathesis": 6.169661660172122, "Hepatic cirrhosis": 5.375563519809614, "Hospitalisation": 10.694966266236486, "Hypervolaemia": 2.727583185079108, "Immune thrombocytopenia": 19.30216738565376, "Immunosuppression": 5.897940324943267, "Increased tendency to bruise": 7.163117585870479, "Iron deficiency anaemia": 2.9426702058616923, "Ischaemic stroke": 2.3602931562124865, "Leukaemia": 5.240278610971806, "Leukocytosis": 10.095916600891856, "Loss of therapeutic response": 11.631305082728998, "Lung cancer metastatic": 11.467003295264314, "Lung infiltration": 2.1311599455599515, "Lung neoplasm malignant": 3.222570331459524, "Lymphoma": 11.45106539331197, "Malnutrition": 6.010383354639162, "Marrow hyperplasia": 37.25801268760016, "Megakaryocytes increased": 116.04096468830942, "Metastases to central nervous system": 2.2319180727125825, "Mouth haemorrhage": 14.5808009714183, "Mucosal haemorrhage": 32.88185867075616, "Multimorbidity": 70.97405534452291, "Myelodysplastic syndrome": 45.83262020298119, "Myelofibrosis": 172.97106796132394, "Myeloproliferative neoplasm": 33.1015936978901, "Neutrophilia": 7.265477843620469, "Non-Hodgkin's lymphoma": 15.2589506438617, "Normochromic normocytic anaemia": 6.497698601778965, "Oedema peripheral": 2.0733133375713244, "Ovarian cancer": 5.093898146353857, "Pancytopenia": 2.8743240396404888, "Petechiae": 13.91609803673088, "Plasma cell myeloma": 3.043583585862543, "Platelet count abnormal": 460.8840840660201, "Platelet count decreased": 23.80966116232555, "Platelet count increased": 57.43959250496793, "Platelet disorder": 28.565846645997446, "Pleural effusion": 4.769263069441014, "Pneumonia": 2.0303820629317406, "Portal hypertension": 6.3400550753037965, "Portal vein thrombosis": 9.267955716133097, "Post procedural complication": 3.8925661779645377, "Pulmonary embolism": 3.889300773120176, "Pulmonary haemorrhage": 4.167726210467282, "Purpura": 4.146955793793382, "Refusal of treatment by patient": 28.88365778285081, "Respiratory failure": 3.5674427997462823, "Sepsis": 4.192723972528166, "Skin haemorrhage": 5.2726423749860265, "Splenectomy": 311.73620254576184, "Splenomegaly": 8.178013985838023, "Subdural haematoma": 3.1179691023027325, "Surgery": 3.460631573381158, "Therapeutic product effect decreased": 6.578052971960744, "Therapeutic response decreased": 83.09796888638398, "Therapy non-responder": 7.144683989776053, "Thrombocytopenia": 7.865301884021775, "Thrombocytosis": 43.84949571751786, "Thrombosis": 4.1292473083755565, "Treatment noncompliance": 2.0192496068647863, "Unevaluable event": 3.153059293777298, "Venous thrombosis": 3.3918256674430105, "Viral infection": 2.617038220945177, "White blood cell count increased": 4.053401208383998}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/788.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/788.json
index 11f6eaad781..0e2adb2155c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/788.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/788.json
@@ -1 +1 @@
-{"Abdominal pain ": 4.280217286548042, "Anal incontinence ": 143.4849730525466, "Arthropathy ": 17.62765613959282, "Back pain ": 6.007984708625272, "Bacterial disease carrier ": 1932.5772961263, "Bronchiectasis ": 179.1479124851229, "Carpal tunnel syndrome ": 134.7226658250234, "Chronic respiratory failure ": 1247.990565363114, "Decubitus ulcer ": 276.19978532385227, "Depression ": 6.944386209982682, "Dysphagia ": 14.487076422584666, "Enterobacter infection ": 1176.461061785761, "Hypertonia ": 158.83610522990733, "Hypoaesthesia ": 6.216929041966256, "Hypothyroidism ": 23.937833835471064, "Hypoxia ": 36.494907587940936, "Implant site erosion ": 4167.916707069352, "Lymphoedema ": 171.59470648540855, "Muscle spasms ": 8.975409337745328, "Muscular weakness ": 10.242025034482634, "Neck pain ": 15.72842707541396, "Nerve compression ": 283.4974384664607, "Neurogenic bladder ": 768.5327563352045, "Neuropathy peripheral ": 14.331397426912698, "Osteonecrosis ": 11.797922540172449, "Pneumonia aspiration ": 61.49413817699495, "Repetitive strain injury ": 10922.780900207154, "Therapeutic response unexpected ": 48.33567229941479, "Urinary tract infection bacterial ": 694.9936888732852}
\ No newline at end of file
+{"Vomiting": 2.773340819407754}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/789.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/789.json
index dea92cf0405..c8cf38d1154 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/789.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/789.json
@@ -1 +1 @@
-{"Agitation ": 2.0781078963859687, "Ankle fracture ": 11.93051982137408, "Balance disorder ": 6.40007148496775, "Burning sensation ": 2.048363051342529, "Colitis ulcerative ": 4.479616177531013, "Cystitis ": 9.502557385770825, "Depressed mood ": 3.943279236267077, "Depression ": 2.663208415682806, "Drug hypersensitivity ": 2.3120015287754905, "Dysuria ": 4.783148104567157, "Fall ": 3.3049713627916786, "Feeling abnormal ": 4.286433740276772, "Flushing ": 8.826861607626638, "Gait disturbance ": 3.157758411947072, "Gait inability ": 3.200188349749077, "Hiatus hernia ": 12.404243996863334, "Hypersomnia ": 10.1666284150812, "Hypoaesthesia ": 2.9323980622877683, "Illness ": 3.0043904013298826, "Immunodeficiency ": 11.728567939078518, "Inflammation ": 3.799330447727375, "Infusion related reaction ": 35.30788970180757, "Lymphocyte count decreased ": 18.01233369918397, "Memory impairment ": 4.090194422574117, "Mental impairment ": 7.43367500524008, "Mobility decreased ": 2.555939187076532, "Multiple sclerosis ": 23.996016100282844, "Multiple sclerosis relapse ": 5.086907429152187, "Muscle spasms ": 3.052193819826842, "Muscular weakness ": 3.4830625458159554, "Musculoskeletal stiffness ": 2.34470884066925, "Nasopharyngitis ": 4.949656553002624, "Neck pain ": 2.500260601103013, "Oropharyngeal pain ": 3.157104655656428, "Osteitis ": 99.13066707064216, "Peroneal nerve palsy ": 51.69733706757736, "Rhinorrhoea ": 3.939346059938994, "Sneezing ": 6.554693245858747, "Somnolence ": 4.509738093834221, "Thrombosis ": 2.1192417828723364, "Tooth disorder ": 15.648369038755764, "Urinary tract infection ": 2.763459031075877}
\ No newline at end of file
+{"Alanine aminotransferase increased": 6.88818400140666, "Aspartate aminotransferase increased": 6.011683966705379, "Blood bilirubin increased": 4.915613131664772, "Decreased appetite": 2.1898933810774945, "Hepatic function abnormal": 6.281596871720396, "Hepatotoxicity": 8.578679038591302, "Hormone-refractory prostate cancer": 1055.486014613139, "Hot flush": 4.145841274519624, "Malignant neoplasm progression": 2.028595623473497, "Metastases to bone": 28.788696981352857, "Neuropathy peripheral": 2.9010470634345724, "Neutropenia": 2.1249958162918565, "Neutrophil count decreased": 5.86333247139274, "Off label use": 4.3125020757053685, "Prostate cancer": 43.88348774865375, "Prostatic specific antigen increased": 166.0449101665958, "Rash": 2.3272378250794428, "Renal impairment": 4.450927974475155}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/79.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/79.json
index 09d839faeb9..9ac0a5bf237 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/79.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/79.json
@@ -1 +1 @@
-{"Acute myocardial infarction ": 9.35550442101695, "Bradycardia ": 3.2330281139724, "Cardiac arrest ": 12.874130494253755, "Cardiac failure ": 2.4778144360344303, "Cardiac tamponade ": 99.2925357550834, "Cardio-respiratory arrest ": 9.684193719005332, "Cardiogenic shock ": 21.47309423000936, "Cerebral haemorrhage ": 6.251988302359264, "Chest pain ": 2.0049694070971675, "Coagulation time abnormal ": 6112.261523717118, "Coagulopathy ": 20.283819701341173, "Coronary artery dissection ": 1089.2542757072365, "Coronary artery occlusion ": 37.35231260250416, "Coronary artery perforation ": 7196.372120109358, "Coronary artery thrombosis ": 731.2447008081293, "Death ": 2.177920083353408, "Device occlusion ": 152.72878465706273, "Device related thrombosis ": 252.83703855717584, "Haematoma ": 7.602528803716543, "Haemoglobin decreased ": 5.936204469293225, "Haemorrhage ": 9.510545799059694, "Haemorrhage intracranial ": 30.169453963045854, "Hypotension ": 3.67527228213373, "International normalised ratio increased ": 11.86043449487409, "Myocardial infarction ": 4.128972686019072, "Off label use ": 2.215416147262464, "Overdose ": 2.990223381675826, "Platelet count decreased ": 2.9170750797567284, "Post procedural haemorrhage ": 34.2588339284578, "Pulmonary haemorrhage ": 62.2819798164794, "Puncture site haemorrhage ": 603.795835892118, "Reperfusion injury ": 2923.133191845433, "Respiratory arrest ": 10.383147837131364, "Respiratory failure ": 4.718220597819974, "Thrombocytopenia ": 3.440307230696157, "Thrombosis ": 15.06689162095558, "Thrombosis in device ": 1411.7258483360908, "Vascular stent thrombosis ": 89.51621675808734, "Ventricular fibrillation ": 28.014567990503814}
\ No newline at end of file
+{"Completed suicide": 94.20060036223455, "Toxicity to various agents": 30.657637203995407}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/790.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/790.json
index b39900a26f0..1476204e454 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/790.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/790.json
@@ -1 +1 @@
-{"Fall ": 3.271074885123871, "Gait disturbance ": 3.4849616183587555, "Intentional product use issue ": 7.445990178470172, "Multiple sclerosis ": 38.058270279091005, "Multiple sclerosis relapse ": 29.09856964033237}
\ No newline at end of file
+{"Accidental exposure to product": 3.519369823198464, "Addison's disease": 54.47180909765106, "Adverse drug reaction": 3.6050401888107575, "Antineutrophil cytoplasmic antibody": 90.44995424394762, "Aphonia": 2.2644666948757504, "Appetite disorder": 2.524921926964301, "Areflexia": 2.728237260225613, "Asphyxia": 2.0573221726643487, "Aspiration": 4.980807844715817, "Asthma": 29.15577114588484, "Asthmatic crisis": 56.59210700077772, "Atelectasis": 7.4834071708121295, "Blood calcium increased": 3.1128842172760964, "Blood immunoglobulin E increased": 4.541901384565106, "Blood lactic acid increased": 40.23136874108019, "Blood potassium decreased": 14.9714765938723, "Blood test abnormal": 5.7733825941672565, "Breath sounds abnormal": 73.42234889322924, "Bronchial hyperreactivity": 6.507246834829061, "Bronchial obstruction": 18.42303380805844, "Bronchial secretion retention": 11.744724825086593, "Bronchial wall thickening": 27.31883763457848, "Bronchiectasis": 13.93446598792309, "Bronchitis": 4.289719848356511, "Bronchopulmonary aspergillosis allergic": 35.26784269707767, "Bronchospasm": 3.588070319856857, "Chest X-ray abnormal": 65.08533851672354, "Chest discomfort": 5.2523496821451845, "Choking": 2.776255233860846, "Chronic obstructive pulmonary disease": 2.746855945362133, "Chronic sinusitis": 8.765574231444646, "Circumstance or information capable of leading to medication error": 2.596815813874458, "Condition aggravated": 2.5505214094480064, "Coronavirus infection": 7.868603527246007, "Coronavirus test positive": 34.8889934152344, "Costochondritis": 2.795017938819732, "Cough": 5.692290896053984, "Crepitations": 5.741751923730332, "Cushingoid": 5.546616085944048, "Cystitis": 7.114349586636779, "Decreased activity": 4.2231260259014585, "Decreased immune responsiveness": 2.0192089599458, "Depressive symptom": 2.383861726131933, "Discouragement": 6.931725638503373, "Disease recurrence": 2.8627836538740583, "Drug effective for unapproved indication": 2.2230263346291266, "Dysphonia": 2.07710235901562, "Dyspnoea": 4.559339859161527, "Dyspnoea exertional": 6.019007166348751, "Ear disorder": 2.4035079270776345, "Ear pruritus": 77.29541078923836, "Eczema": 3.316493324358444, "Emergency care": 7.679397107297966, "Emphysema": 4.240826271551405, "Endotracheal intubation": 2.1449736692008634, "Eosinophil count abnormal": 47.38852674578952, "Eosinophil count decreased": 10.033321497836273, "Eosinophil count increased": 15.994543648270492, "Eosinophilia": 9.325180207289105, "Eosinophilic granulomatosis with polyangiitis": 10.79423536000895, "Exercise tolerance decreased": 2.5725317728028347, "Exposure via skin contact": 68.97919537889388, "Eye paraesthesia": 34.24220619107173, "Eye pruritus": 16.467247757577596, "Eye swelling": 4.587831830205932, "Facial discomfort": 5.500505723368943, "Fear of injection": 16.93688311650925, "Forced expiratory volume decreased": 10.258847266428669, "Forced expiratory volume increased": 101.01952374079964, "Forced vital capacity decreased": 33.53279246580824, "Full blood count abnormal": 48.48616911498753, "Glaucoma": 3.116719346550308, "Glucose tolerance impaired": 3.800430589881909, "Goitre": 3.522080705592737, "Haemophilus infection": 25.800555354328807, "Haemoptysis": 4.944253392353406, "Heart sounds": 38.85933927237095, "Hospitalisation": 4.698772421384198, "Hypereosinophilic syndrome": 21.39584069217388, "Hypersensitivity pneumonitis": 5.43856593908761, "Hypoventilation": 5.314417654709579, "Ill-defined disorder": 2.1134315188815878, "Illness": 2.0981302588873283, "Immune system disorder": 4.317294420820848, "Impaired quality of life": 2.710835760957862, "Inappropriate schedule of product administration": 3.283650200129005, "Increased bronchial secretion": 3.163762660904344, "Increased upper airway secretion": 5.661340844195672, "Increased viscosity of upper respiratory secretion": 6.835419761778538, "Infection": 2.154654722163837, "Injection site discomfort": 3.3055130645454462, "Kidney infection": 10.880218607146556, "Lacrimation increased": 10.842513869207842, "Laryngeal disorder": 12.049593771334049, "Loss of personal independence in daily activities": 21.008974711478345, "Lower respiratory tract infection": 3.503039400577626, "Lung consolidation": 3.351967692458106, "Lung disorder": 3.49290543152562, "Lung hernia": 425.48306916958666, "Lung opacity": 4.19963633319571, "Mean cell volume decreased": 6.053015161180841, "Middle insomnia": 6.167714308246097, "Multiple allergies": 10.540513823233749, "Mycobacterial infection": 5.733980198805928, "Mycobacterium avium complex infection": 5.357423256200751, "Nasal congestion": 11.973440876208135, "Nasal disorder": 15.867583288581526, "Nasal obstruction": 2.989867115279014, "Nasal oedema": 6.441097638172392, "Nasal polyps": 86.44376309799632, "Nasal septum deviation": 12.097095098089298, "Nasopharyngitis": 2.93835437625232, "Night sweats": 3.4805247397760257, "Nocturnal dyspnoea": 5.380706712690678, "Obstructive airways disorder": 28.874289044793844, "Ocular discomfort": 4.523893455464834, "Ocular hyperaemia": 2.011637721448344, "Oesophageal disorder": 8.337202242597664, "Oral candidiasis": 2.9505223142673715, "Oral disorder": 2.76781797281798, "Orthopnoea": 2.151616178639977, "Otitis media": 2.0292023650904567, "Otitis media chronic": 12.183794627793748, "Oxygen saturation abnormal": 3.529396839063053, "Oxygen saturation decreased": 3.268940054216669, "Paranasal sinus discomfort": 14.613319935169656, "Peak expiratory flow rate decreased": 27.071764554749254, "Personal relationship issue": 38.66495147089283, "Pharyngeal erythema": 4.98988916409075, "Pharyngitis": 3.374091730374153, "Platelet count increased": 21.68549296758328, "Pleuritic pain": 3.850794541975483, "Pneumonia": 2.5841528113111263, "Pneumonia bacterial": 2.4555279989246537, "Polyp": 3.761794322397233, "Product availability issue": 9.033012350582178, "Product complaint": 3.6130956203232474, "Product dose omission issue": 7.256806088009834, "Product supply issue": 2.7060513443814163, "Productive cough": 20.492191318625213, "Prolonged expiration": 34.61917093894282, "Psychiatric symptom": 5.275976231333815, "Pulmonary congestion": 5.166053914677019, "Pulmonary function test abnormal": 119.65099636851362, "Pulmonary function test decreased": 5.464333052638083, "Pulmonary mass": 6.687326595817944, "Quality of life decreased": 7.689225857265576, "Quarantine": 86.03756735730167, "Radius fracture": 4.711926207484267, "Rales": 2.927705215072991, "Rash erythematous": 2.3043742993207808, "Respiration abnormal": 3.4636639907880054, "Respiratory disorder": 2.868820589208949, "Respiratory symptom": 12.578101933184485, "Respiratory tract congestion": 2.9106930629131647, "Respiratory tract infection": 6.310682643521073, "Respiratory tract inflammation": 17.543568887843726, "Restrictive pulmonary disease": 14.665423541525032, "Reversible airways obstruction": 13.901269795794256, "Rhinitis": 4.079836784001023, "Rhinitis allergic": 33.92274209504966, "Rhinorrhoea": 7.340765599905777, "Rhonchi": 8.89771712146486, "Scratch": 5.725738890044616, "Seasonal allergy": 12.060427134334642, "Secretion discharge": 11.178679621059947, "Sense of oppression": 5.053346913759841, "Sensitivity to weather change": 4.192510089486671, "Sinonasal obstruction": 34.27280128008389, "Sinus congestion": 4.596771943402864, "Sinus disorder": 2.558417976471242, "Sinus operation": 8.957993134600617, "Sinusitis": 5.583323919399732, "Skin fragility": 16.470920461925434, "Skin laceration": 2.062495959596426, "Sleep disorder": 2.591808000766169, "Sleep disorder due to a general medical condition": 65.68343507466813, "Sneezing": 16.02054114837622, "Social problem": 17.17012493855582, "Spirometry abnormal": 14.507027001928282, "Sputum abnormal": 8.197821822406942, "Sputum discoloured": 26.592438097485545, "Sputum purulent": 16.44481303103854, "Sputum retention": 21.646203144292397, "Surgery": 2.310103549922403, "Symptom recurrence": 4.962793229381355, "Therapeutic product effect incomplete": 24.439801827157947, "Therapeutic response decreased": 3.2406581028792245, "Therapy cessation": 4.222861213798744, "Therapy interrupted": 11.78809867421868, "Total lung capacity increased": 12.573680501635623, "Tracheomalacia": 17.984880750129616, "Tumour excision": 12.910865108096008, "Upper respiratory tract congestion": 6.574447429087747, "Upper respiratory tract infection": 3.221589847963115, "Upper-airway cough syndrome": 64.26177324892365, "Urinary tract disorder": 4.845669594143235, "Use of accessory respiratory muscles": 38.41100752539437, "Vasculitis": 13.470699139592597, "Viral infection": 2.2812476905953667, "Vital capacity decreased": 37.20407930802459, "Vocal cord dysfunction": 10.759292845133167, "Vulvovaginal candidiasis": 2.583251620723296, "Wheezing": 37.886920238205946, "Wrong technique in device usage process": 7.751502087395275}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/791.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/791.json
index b7995706300..eaf56c2ec10 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/791.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/791.json
@@ -1 +1 @@
-{"Anti factor VIII antibody positive ": 4529.024532274634, "Drug ineffective ": 7.684214562875225, "Factor VIII inhibition ": 1707.5779513017712}
\ No newline at end of file
+{"Vomiting": 2.348101765958025}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/792.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/792.json
index bd9f21a4c92..60815bd786c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/792.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/792.json
@@ -1 +1 @@
-{"Abdominal distension ": 3.718576062726355, "Bone pain ": 4.514649864366543, "Cholelithiasis ": 19.996518143655745, "Disease progression ": 2.839871820071082, "Disseminated intravascular coagulation ": 19.71523571605949, "Drug reaction with eosinophilia and systemic symptoms ": 7.935000261638885, "Epistaxis ": 2.7555047985676877, "Heart rate decreased ": 11.257876641843296, "Hyperglycaemia ": 6.794022826848816, "Illness ": 4.5321324450549, "Malignant neoplasm progression ": 6.346768049164015, "Metastases to liver ": 19.263468254725467, "Post procedural haemorrhage ": 40.42174416181631, "Product use in unapproved indication ": 2.309634455269961, "Rectal haemorrhage ": 6.984364082233032, "Sepsis ": 6.38044491014}
\ No newline at end of file
+{"Myalgia": 4.250344691869928}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/793.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/793.json
index 43e66a0054c..79a80c5f04e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/793.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/793.json
@@ -1 +1 @@
-{"Anaemia ": 2.8867400411180806, "Chronic lymphocytic leukaemia ": 170.2732843630645, "Diffuse large B-cell lymphoma ": 96.02542075337604, "Diffuse large B-cell lymphoma recurrent ": 218.4133132089203, "Malignant neoplasm progression ": 7.042521180092629, "Neutropenia ": 2.618424355129595, "Pneumonia ": 2.2505228850080816, "Product use in unapproved indication ": 15.181705285752845, "Throat irritation ": 12.142701430593592, "Toxicity to various agents ": 3.286302126994183}
\ No newline at end of file
+{"Epiphysiolysis": 882.160968263104, "Intracranial pressure increased": 66.21940442186816, "Meningioma": 137.41681124373372, "Pneumonia": 2.8336723434818083, "Scoliosis": 165.5105509865673, "Seizure": 2.8777113287838336}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/794.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/794.json
index 2cf778e9124..fcea83f5df2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/794.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/794.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.292965435047865, "Abdominal distension ": 2.052415346549608, "Abdominal pain ": 2.953012582476298, "Abdominal pain upper ": 2.7787216174869185, "Abnormal loss of weight ": 9.189783815760324, "Acute coronary syndrome ": 4.000394916872363, "Acute myocardial infarction ": 2.8617991978765023, "Acute respiratory failure ": 2.695192903565324, "Anal incontinence ": 2.206531905684396, "Blood pressure diastolic abnormal ": 13.753948699635435, "COVID-19 pneumonia ": 2.2884836677368563, "Chronic respiratory failure ": 19.23280302137393, "Constipation ": 3.2903745057308997, "Coronavirus infection ": 3.8549080581601096, "Cough ": 2.682697929912185, "Death ": 7.147434911904626, "Decreased appetite ": 6.200385622608918, "Diarrhoea ": 13.028577007205682, "Diarrhoea haemorrhagic ": 2.884805684208494, "Diverticulitis ": 3.2795509670615868, "Dyspepsia ": 3.006162773041564, "Dyspnoea exertional ": 8.314153551343185, "Epistaxis ": 2.2470087561358683, "Faeces discoloured ": 2.76097139749974, "Faeces soft ": 27.11674947633393, "Flatulence ": 5.593547113798278, "Forced vital capacity decreased ": 89.14292732257697, "Gamma-glutamyltransferase increased ": 4.293371678104928, "Gastric haemorrhage ": 2.6180614604235624, "Gastrointestinal disorder ": 5.779469064507282, "Gastrointestinal pain ": 2.742896542182305, "Gastrointestinal perforation ": 4.392510452123849, "Gastrointestinal sounds abnormal ": 4.484790637477156, "General physical health deterioration ": 2.2713233192511337, "Haemoptysis ": 3.524722204336436, "Hepatic cytolysis ": 2.5698406498407995, "Hepatic enzyme increased ": 5.231652055886028, "Hepatotoxicity ": 3.9754868498428086, "Hip fracture ": 3.044727896251443, "Hypertransaminasaemia ": 7.158299680220993, "Hypophagia ": 4.469428165076442, "Hypoxia ": 2.2809805020470924, "Idiopathic pulmonary fibrosis ": 650.3447195237708, "Interstitial lung disease ": 2.848202196193612, "Intestinal perforation ": 4.069453398153047, "Investigation abnormal ": 18.684351061546703, "KL-6 increased ": 15.814963824351024, "Liver disorder ": 2.3109187802046227, "Liver function test abnormal ": 2.7050995841816503, "Liver function test increased ": 9.71141303055552, "Lower gastrointestinal haemorrhage ": 2.404607702312918, "Lung diffusion test decreased ": 39.5815663846807, "Lung disorder ": 4.593783756963166, "Lung neoplasm malignant ": 5.500278878535834, "Lung transplant ": 51.13058623378122, "Myocardial infarction ": 2.170622258264545, "Nausea ": 2.121303412956336, "Nephrotic syndrome ": 2.398954613152664, "Oxygen consumption increased ": 26.952328427651786, "Oxygen saturation decreased ": 7.071504980995843, "Physical deconditioning ": 9.419122685306077, "Pneumomediastinum ": 12.962014744564977, "Pneumonia ": 2.949082973703358, "Pneumothorax ": 12.751779894493763, "Post procedural complication ": 2.691475955140743, "Productive cough ": 7.921496209644519, "Pulmonary arterial hypertension ": 3.181696056288685, "Pulmonary fibrosis ": 10.79908655657334, "Pulmonary function test decreased ": 16.866008493366138, "Pulmonary hypertension ": 8.38786401808802, "Pulseless electrical activity ": 14.659397352398202, "Respiratory disorder ": 2.173575047090299, "Respiratory failure ": 4.068766326553877, "Respiratory rate increased ": 3.1611292400371265, "Right ventricular failure ": 4.051303740074024, "Scleroderma ": 8.986190619908276, "Seasonal allergy ": 3.507581480832375, "Sputum discoloured ": 2.947600543336244, "Taste disorder ": 2.0028583095256924, "Tooth infection ": 3.696739249755713, "Transaminases increased ": 8.834659061321089, "Transient ischaemic attack ": 2.369054124380918, "Varicose vein ": 3.4721469064555444, "Vomiting ": 2.462672681721218, "Weight decreased ": 12.07469519066245}
\ No newline at end of file
+{"Injection site haematoma": 67.45453114642442, "Injection site pain": 7.47982899459913}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/795.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/795.json
index e24fcd5ea27..274cf2ffc85 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/795.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/795.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 5.2419048816385, "Abnormal weight gain ": 11.246950159165372, "Abulia ": 5.886206226120309, "Accidental death ": 80.61733219893797, "Accidental exposure to product by child ": 5.823193115990974, "Accidental overdose ": 3.273911711555235, "Acute psychosis ": 5.765437993356041, "Acute pulmonary oedema ": 2.4004492326908715, "Affect lability ": 3.424144708205358, "Affective disorder ": 4.633541349463407, "Aggression ": 6.04988281386844, "Agitated depression ": 36.11741074022127, "Agitation ": 5.860586630882987, "Agitation neonatal ": 9.707724095089349, "Agranulocytosis ": 2.334557891442586, "Akathisia ": 21.53859848925718, "Akinesia ": 6.136929522745733, "Alanine aminotransferase increased ": 2.1849079482094584, "Alcohol withdrawal syndrome ": 15.003346999506974, "Altered state of consciousness ": 3.4109151356141263, "Amimia ": 48.025924027778274, "Ammonia increased ": 2.901280505008553, "Anosognosia ": 11.127151250086804, "Anticholinergic syndrome ": 65.76881218578033, "Antiphospholipid antibodies ": 32.25696391938091, "Antipsychotic drug level below therapeutic ": 3.4954684399884868, "Antipsychotic drug level increased ": 19.266132377911028, "Antisocial behaviour ": 8.959125441339296, "Apallic syndrome ": 6.864923034946712, "Apathy ": 3.939502746445686, "Areflexia ": 3.113231895045645, "Arteriosclerosis coronary artery ": 2.2989359988665967, "Aspartate aminotransferase increased ": 2.1454491163332845, "Asphyxia ": 2.4335233979392616, "Aspiration ": 4.270124471329763, "Ataxia ": 2.7552988641642573, "Atrioventricular block first degree ": 2.317278643333808, "Atrioventricular septal defect ": 13.633059911382356, "Autonomic nervous system imbalance ": 7.107026321384545, "Behaviour disorder ": 3.74630776013136, "Benign ethnic neutropenia ": 268.9572815303201, "Bezoar ": 12.69115397249462, "Bipolar I disorder ": 20.51866285655935, "Bipolar disorder ": 6.2101257248433255, "Blood bicarbonate decreased ": 3.054626961801964, "Blood chloride decreased ": 3.002825638621942, "Blood chloride increased ": 3.0919741061681267, "Blood creatine phosphokinase MB increased ": 3.908728399079709, "Blood creatine phosphokinase increased ": 7.899807788702598, "Blood osmolarity increased ": 9.231411979906357, "Blood prolactin increased ": 29.073941991485032, "Blood sodium increased ": 6.541851133824914, "Blood triglycerides increased ": 4.521105132450023, "Blood urea decreased ": 13.90761467769775, "Blunted affect ": 16.254253827353367, "Body mass index increased ": 8.07268986998991, "Borderline personality disorder ": 11.509861677372, "Bradykinesia ": 20.263084058876075, "Bradyphrenia ": 2.3138872649264988, "Brain death ": 3.165511673955791, "Brain injury ": 3.004951386655479, "Brain oedema ": 2.376411346632072, "Bundle branch block right ": 2.7729175962758785, "Camptocormia ": 84.78663070257144, "Cardiac arrest ": 2.605185644985282, "Cardio-respiratory arrest ": 5.881980776594869, "Cardiomyopathy ": 4.186961524971776, "Catatonia ": 47.71680434909285, "Cerebellar atrophy ": 4.422468660015504, "Cerebral atrophy ": 3.8895803964417466, "Cerebral ischaemia ": 2.0264991344839265, "Chorea ": 4.670603461658708, "Clonus ": 6.949665684448042, "Cognitive disorder ": 3.51444429254314, "Cogwheel rigidity ": 34.11785841693764, "Colitis ischaemic ": 4.194947631464654, "Coma ": 5.460787019478733, "Coma scale abnormal ": 8.067559918326827, "Communication disorder ": 4.92814037139773, "Compartment syndrome ": 4.712936222785347, "Completed suicide ": 9.062449783459076, "Confusional state ": 2.47957690537733, "Consciousness fluctuating ": 9.429362502258442, "Decreased interest ": 3.404417598105121, "Decubitus ulcer ": 2.8332524394686125, "Delirium ": 6.626404500487753, "Delusion ": 14.141258067707325, "Delusion of grandeur ": 18.813203501731092, "Delusion of replacement ": 120.23698780931264, "Dementia with Lewy bodies ": 26.069378498150364, "Depressed level of consciousness ": 4.707869162000302, "Depressive symptom ": 2.476345667833245, "Derealisation ": 2.692353059626565, "Diabetes insipidus ": 3.785527016663176, "Diabetes mellitus ": 3.1691932370526965, "Diabetic ketoacidosis ": 2.634341098214647, "Discoloured vomit ": 30.92079707612087, "Disinhibition ": 5.750037767893161, "Disorganised speech ": 2.486484061739235, "Disorientation ": 2.9804685547471754, "Disturbance in social behaviour ": 4.405441948850473, "Drooling ": 3.4997817277510266, "Drug abuse ": 4.671947589421734, "Drug interaction ": 4.2991842755337215, "Drug level above therapeutic ": 9.74909543278086, "Drug level increased ": 4.030026095105472, "Drug screen positive ": 3.654101336807519, "Drug withdrawal syndrome neonatal ": 3.501615035932806, "Drug-induced liver injury ": 2.3838026552214964, "Dysarthria ": 4.363400018441745, "Dyskinesia ": 6.049791328036221, "Dyslipidaemia ": 4.651356975304616, "Dysphemia ": 2.918834384814183, "Dysphoria ": 2.817686011247777, "Dystonia ": 16.799632656291084, "Electrocardiogram QRS complex prolonged ": 5.405784864839431, "Electrocardiogram QT prolonged ": 7.857470223806124, "Electrocardiogram T wave inversion ": 3.395041870017632, "Electrocardiogram abnormal ": 3.819595401994779, "Electroencephalogram abnormal ": 4.943405819363087, "Embolism venous ": 15.407549221040592, "Encephalitis autoimmune ": 2.396197975952264, "Endotracheal intubation ": 3.365308209875552, "Enuresis ": 2.615079368620928, "Eosinophil count decreased ": 5.101034076783346, "Euphoric mood ": 6.380709884814332, "Excessive eye blinking ": 8.235463546387367, "Extrapyramidal disorder ": 31.59042515538941, "Eye movement disorder ": 2.072099087014061, "Faecaloma ": 6.012244796546263, "Feeling guilty ": 13.111634603880336, "Flat affect ": 4.068530612828039, "Flight of ideas ": 30.211421559429255, "Fluid intake reduced ": 2.7311109480522857, "Foaming at mouth ": 2.260484008020889, "Foetal exposure timing unspecified ": 4.034864742812943, "Food craving ": 4.02002232787715, "Frustration tolerance decreased ": 4.37571448607221, "Galactorrhoea ": 8.440105828096973, "Gastrointestinal hypomotility ": 10.899062263753558, "Gastrointestinal necrosis ": 2.9361393491811647, "Gastrointestinal sounds abnormal ": 5.160806530250731, "Gaze palsy ": 3.1894547602953405, "Generalised anxiety disorder ": 5.024530229898881, "Generalised tonic-clonic seizure ": 2.8720648107859748, "Gestational diabetes ": 9.594948023581908, "Glucose urine present ": 4.372717211170411, "Grandiosity ": 19.55065459329453, "Granulocytopenia ": 4.1550398468896415, "Gynaecomastia ": 2.882632510130985, "Haematocrit increased ": 2.2046835363884574, "Haemodynamic instability ": 2.6228083299362384, "Hallucination ": 2.0077639336146538, "Hallucination, auditory ": 12.94495663122712, "Hallucination, visual ": 3.3036845719371994, "Hanging ": 26.64269980674093, "Heat stroke ": 11.72495542151455, "Hepatic enzyme abnormal ": 2.067889832339695, "Hepatic function abnormal ": 3.748057436574508, "Hepatic steatosis ": 2.371827513534692, "High density lipoprotein decreased ": 3.141827113146035, "Hirsutism ": 8.276375450815959, "Homicide ": 5.19260360471046, "Hostility ": 7.582985114456718, "Humerus fracture ": 3.332607799779309, "Hunger ": 2.1589850595903157, "Hyperammonaemia ": 3.912178137018149, "Hyperammonaemic encephalopathy ": 6.6487667932534125, "Hyperglycaemic hyperosmolar nonketotic syndrome ": 12.930321377973245, "Hyperlipidaemia ": 2.745891013859869, "Hypernatraemia ": 6.286318490075148, "Hyperphagia ": 7.081396549179476, "Hyperprolactinaemia ": 39.34228162824216, "Hyperreflexia ": 8.815765780569599, "Hypersomnia ": 2.29371299075397, "Hyperthermia ": 9.635199522821653, "Hypertonia ": 7.773807210478494, "Hypertriglyceridaemia ": 5.820701599233047, "Hyperuricaemia ": 3.793125129361596, "Hypoalbuminaemia ": 2.238354369643893, "Hypocalcaemia ": 2.199427413226372, "Hypomania ": 7.622981146320928, "Hyponatraemia ": 2.579177164353873, "Hypophagia ": 3.0593361504695524, "Hyporeflexia ": 2.223539220828348, "Hypothermia ": 7.957704254517482, "Hypotonia neonatal ": 5.8236503102731785, "Hypoventilation ": 4.83560549183394, "Hypoxic-ischaemic encephalopathy ": 3.42564366408953, "Ileus paralytic ": 8.155465312920613, "Illusion ": 2.8556700212093324, "Immobile ": 2.45125955451049, "Impulsive behaviour ": 8.136177134481038, "Inappropriate antidiuretic hormone secretion ": 4.98296706928932, "Incoherent ": 2.9484518453631647, "Incontinence ": 2.407502371630319, "Increased appetite ": 9.939609644550854, "Increased bronchial secretion ": 3.335935127303889, "Intentional overdose ": 7.554817683992456, "Intentional product misuse ": 2.1397681211237107, "Intentional self-injury ": 7.8334947877281875, "Intestinal obstruction ": 2.750556602696021, "Intestinal pseudo-obstruction ": 11.010588333359712, "Irritability ": 2.665301663549413, "Judgement impaired ": 7.769870232645914, "Ketonuria ": 4.960717835746749, "Labelled drug-drug interaction issue ": 6.417893443804156, "Labelled drug-food interaction medication error ": 32.27977575299081, "Labile blood pressure ": 4.762087110553849, "Large intestinal obstruction ": 10.07359796062237, "Leukocyte adhesion deficiency ": 549.0021310917658, "Leukocytosis ": 4.959125689385736, "Leukopenia ": 3.029217321782993, "Libido increased ": 5.217943264426953, "Lipids increased ": 4.002983003452871, "Liver function test abnormal ": 2.0787003756372027, "Logorrhoea ": 3.6690582505569904, "Long QT syndrome ": 8.324889743984125, "Lymphocyte count decreased ": 4.587936696652833, "Major depression ": 5.48732768183777, "Mania ": 10.67150246896983, "Megacolon ": 9.863359753195429, "Meige's syndrome ": 45.43331266053788, "Mental disorder ": 2.301161431964491, "Mental impairment ": 4.100979165589343, "Mental status changes ": 5.563457302871587, "Metabolic disorder ": 6.069100583928666, "Metabolic syndrome ": 34.31149637455153, "Miosis ": 9.239520544131192, "Moaning ": 4.474733129885358, "Mood altered ": 2.074365282628174, "Mucosal dryness ": 3.957270193394228, "Muscle contractions involuntary ": 2.18623094350606, "Muscle rigidity ": 19.99866088674353, "Mutism ": 20.679661105866614, "Mydriasis ": 2.9582860582218924, "Myocardial hypoxia ": 254.2373242522463, "Myocardial reperfusion injury ": 397.16674798978426, "Myoclonic epilepsy ": 3.88617027874296, "Myoclonus ": 3.424352993200118, "Myoglobin blood increased ": 2.2296958012160566, "Myoglobinuria ": 8.891634435323578, "Negativism ": 30.977487753246205, "Neonatal respiratory distress ": 2.867014376658946, "Nephrogenic diabetes insipidus ": 4.34623811162273, "Neuroleptic malignant syndrome ": 56.44518718288362, "Neutropenia ": 2.40461590457212, "Neutrophil count increased ": 6.995768602379992, "Neutrophilia ": 3.442482096648433, "Normal newborn ": 2.87799180720436, "Obesity ": 5.668834166547385, "Obsessive thoughts ": 6.924538703314073, "Obsessive-compulsive disorder ": 11.01658567352957, "Obsessive-compulsive symptom ": 47.47952688971287, "Oculogyric crisis ": 25.772206569072985, "Opisthotonus ": 4.452592573666275, "Oromandibular dystonia ": 13.729124271715389, "Orthostatic hypotension ": 2.933419926990098, "Ovarian cancer ": 2.6596420955391373, "Overdose ": 4.315073173179077, "Overweight ": 5.306813913390497, "Painful erection ": 25.293361852981807, "Pancreatic neuroendocrine tumour metastatic ": 11.680702112028191, "Pancreatitis haemorrhagic ": 10.231150068199211, "Pancreatitis necrotising ": 5.879915436039491, "Paranoia ": 5.36353819543423, "Parkinsonian gait ": 10.39507516048998, "Parkinsonian rest tremor ": 19.91414013769362, "Parkinsonism ": 25.270518300614523, "Paternal exposure timing unspecified ": 10.93077297010494, "Persecutory delusion ": 19.83305203951076, "Personality disorder ": 3.244798425416371, "Phagophobia ": 205.8791551113204, "Phobia ": 7.324603873684357, "Pituitary tumour benign ": 5.49796598715079, "Pleurothotonus ": 69.58405259296852, "Pneumonia aspiration ": 6.485847307012103, "Pneumonitis aspiration ": 9.08012560922131, "Poisoning ": 7.454475427875071, "Poisoning deliberate ": 9.653937600898152, "Polydipsia ": 7.217015639482775, "Polydipsia psychogenic ": 26.074045327665026, "Polyuria ": 2.2375607622588274, "Post-injection delirium sedation syndrome ": 20.932082239866972, "Post-traumatic stress disorder ": 2.308234006745232, "Postoperative ileus ": 28.413322761654747, "Posture abnormal ": 13.451442547437908, "Prescribed overdose ": 6.759460124181447, "Pressure of speech ": 22.70129626412294, "Priapism ": 26.895689545416836, "Product communication issue ": 14.089062967658434, "Product monitoring error ": 8.01080142083515, "Product substitution issue ": 2.278071779154693, "Progressive supranuclear palsy ": 41.07468947631209, "Protrusion tongue ": 11.507858120138104, "Psychiatric decompensation ": 14.85222806556086, "Psychiatric symptom ": 5.079072930928464, "Psychomotor hyperactivity ": 5.808412534572094, "Psychomotor retardation ": 12.185465414783588, "Psychotic behaviour ": 10.31930889480686, "Psychotic disorder ": 10.875990363254797, "Psychotic symptom ": 39.66808173952492, "Pulmonary congestion ": 6.12920825377303, "Pulmonary embolism ": 2.3233143192781363, "Pulse absent ": 5.014710812951462, "Pupil fixed ": 3.603821993950385, "Quadriparesis ": 3.937688202581549, "Rebound effect ": 6.256105129507945, "Rebound psychosis ": 106.88922511972568, "Red blood cell count increased ": 3.3472621968584666, "Reduced facial expression ": 11.51494444522018, "Respiratory acidosis ": 3.5412625369690804, "Respiratory arrest ": 3.744397413722359, "Respiratory depression ": 4.45453561669157, "Respiratory distress ": 2.3129881330409603, "Resting tremor ": 34.27230214968965, "Restless legs syndrome ": 2.7539236015705137, "Restlessness ": 3.2272650263223235, "Rhabdomyolysis ": 4.960702451954989, "Salivary hypersecretion ": 11.735021841450695, "Schizoaffective disorder ": 17.628727100045325, "Schizophrenia ": 42.381292504494816, "Sedation ": 15.90604910459032, "Sedation complication ": 12.236265745247112, "Selective eating disorder ": 7.248597172564195, "Self-destructive behaviour ": 7.412572695582197, "Self-injurious ideation ": 8.087415747447604, "Self-medication ": 3.2192548459282504, "Seminoma ": 58.66441877481463, "Serotonin syndrome ": 8.54553092411087, "Sexual dysfunction ": 2.7635160233447804, "Sexually inappropriate behaviour ": 26.616447736462533, "Sinus bradycardia ": 2.123597058103172, "Sinus rhythm ": 5.454552729669046, "Sinus tachycardia ": 5.192586654556625, "Slow response to stimuli ": 2.895345675844349, "Slow speech ": 3.910898243416053, "Sluggishness ": 2.8677380398758623, "Small for dates baby ": 3.4459214675349013, "Snoring ": 2.157603759288647, "Social avoidant behaviour ": 5.602915092644413, "Somatic delusion ": 79.8906018459257, "Somatic symptom disorder ": 2.7480651906108675, "Somnambulism ": 5.7574073115956, "Somnolence ": 3.6051522537141913, "Sopor ": 6.3811161769568, "Spasmodic dysphonia ": 62.15194642266471, "Speech disorder ": 2.855620406661849, "Stenosis ": 5.312404302100536, "Stupor ": 3.687672587905474, "Substance-induced psychotic disorder ": 22.212046276659617, "Sudden cardiac death ": 14.035715310762845, "Sudden death ": 3.5164558949664677, "Suicidal behaviour ": 3.7922439842708897, "Suicidal ideation ": 2.6097991421378803, "Suicide attempt ": 5.049573598934948, "Suspected suicide ": 9.95785460917635, "Suspiciousness ": 25.30100663086496, "Systolic dysfunction ": 4.341338407462684, "Tachycardia ": 2.515647125976313, "Tachyphrenia ": 2.6401312264251247, "Tachypnoea ": 3.702502457495119, "Talipes ": 2.440000705024947, "Tardive dyskinesia ": 35.111911796354974, "Tension ": 2.923917671602552, "Therapy non-responder ": 2.181324211627683, "Thinking abnormal ": 4.254875081280143, "Tobacco interaction ": 112.26635843984668, "Tongue biting ": 3.2966425279324736, "Tonic convulsion ": 2.711712706108903, "Torsade de pointes ": 5.666907076393908, "Torticollis ": 11.14843886135258, "Toxicity to various agents ": 8.097498045037192, "Transaminases increased ": 2.776748634753388, "Treatment noncompliance ": 6.938691579312748, "Tremor ": 2.26519675361044, "Troponin T increased ": 3.7262373177769006, "Troponin increased ": 4.913117012979564, "Type 1 diabetes mellitus ": 2.2965221425861517, "Type 2 diabetes mellitus ": 3.0062617417180237, "Unresponsive to stimuli ": 4.835882599316331, "Urinary hesitation ": 2.512166259223931, "Urinary incontinence ": 2.2507077602968293, "Urinary retention ": 2.807135647745135, "Vascular neoplasm ": 111.0995887837676, "Ventricular arrhythmia ": 4.67490220093029, "Violence-related symptom ": 7.465011213617355, "Water intoxication ": 12.226337145241295, "Weight increased ": 7.9049412818814, "White blood cell count increased ": 3.8552802304920464, "Withdrawal syndrome ": 2.71668153838363, "Wrong patient ": 17.458444581781713, "Wrong patient received product ": 11.013083263651046, "Xanthoma ": 34.39158731469135}
\ No newline at end of file
+{"Gamma-glutamyltransferase abnormal": 1002.8322798423314, "Hepatic cirrhosis": 52.45252841805807, "Product dose omission issue": 6.862924498692259, "Pruritus": 12.69322327690324}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/796.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/796.json
index f2a35bce6b1..e4bbb3bb673 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/796.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/796.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 18.25791755637005, "Alanine aminotransferase increased ": 2.6815610492767963, "Anaemia ": 23.27578665585569, "Asthenia ": 2.6356532768473744, "Carbohydrate antigen 125 increased ": 103.72063657122432, "Disease progression ": 3.049097229638003, "Drug resistance ": 8.319354230066157, "Dyspnoea exertional ": 2.6853782465150915, "Haematotoxicity ": 31.78129426960385, "Haemoglobin abnormal ": 28.3281796527241, "Haemoglobin decreased ": 5.354272763753961, "Leukopenia ": 7.88560598918799, "Lymphopenia ": 14.303938738756528, "Malignant neoplasm progression ": 20.91696188034176, "Metastases to bone ": 14.81828111570877, "Metastases to central nervous system ": 13.157402366366735, "Metastases to liver ": 20.452640339256494, "Metastases to lung ": 14.223318352326697, "Metastases to lymph nodes ": 16.58734584391089, "Metastases to pelvis ": 142.41297073437656, "Metastases to spine ": 41.00453127641667, "Myelodysplastic syndrome ": 84.84470807194162, "Myelosuppression ": 10.070589398960326, "Nausea ": 2.379809113658327, "Neutropenia ": 6.662389274626959, "Off label use ": 3.261221889821022, "Ovarian cancer recurrent ": 228.7139975240651, "Pancytopenia ": 5.098888063138287, "Platelet count decreased ": 2.806226231860063, "Pneumonitis ": 6.580111946942954, "Product use in unapproved indication ": 3.247397749063283, "Prostatic specific antigen increased ": 9.581649539149394, "Red blood cell count decreased ": 5.361850044180246, "Thrombocytopenia ": 8.613044668658455, "White blood cell count decreased ": 3.089787173753777}
\ No newline at end of file
+{"Anaemia": 3.04461810338983, "COVID-19": 3.140326118290389, "COVID-19 pneumonia": 35.547773488051604, "Cardiac disorder": 3.986779381085997, "Chest discomfort": 2.088904708301788, "Chronic lymphocytic leukaemia": 32.85476772337904, "Cytokine release syndrome": 4.613834293176742, "Cytomegalovirus chorioretinitis": 38.14957595414204, "Cytomegalovirus infection": 11.536225675524626, "Diffuse large B-cell lymphoma": 16.381827453046256, "Disease progression": 10.809035855524188, "Encephalopathy": 3.36156516715479, "Febrile neutropenia": 15.055158129567705, "Follicular lymphoma": 363.2573263171178, "Haematotoxicity": 12.510331163226136, "Hypogammaglobulinaemia": 55.98488618870621, "Hypotension": 2.118104609803781, "Infection": 2.104484747780238, "Infusion related reaction": 23.44582970320656, "Intentional product use issue": 3.3335878198901407, "Lower respiratory tract infection": 3.6044861194639073, "Lymphocyte count decreased": 21.73966608870621, "Myelosuppression": 9.993352816734342, "Neutropenia": 17.505320606270345, "Neutropenic sepsis": 26.11896152102213, "Neutrophil count decreased": 7.683365102059168, "Off label use": 4.03392825802929, "Oxygen saturation decreased": 3.634369929039126, "Pancytopenia": 2.248656063809772, "Platelet count decreased": 5.313792504208246, "Pneumonia": 5.5362657128565536, "Prescribed underdose": 59.929557590833554, "Progressive multifocal leukoencephalopathy": 24.636375546315737, "Septic shock": 4.43836908477213, "Therapy partial responder": 17.4979119892943, "Thrombocytopenia": 8.374844100160594, "Tumour lysis syndrome": 105.11442352676312, "Urinary tract infection": 2.4348901757067654, "White blood cell count decreased": 3.640182497062746}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/797.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/797.json
index bcb0c101a30..78e53ed6ed3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/797.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/797.json
@@ -1 +1 @@
-{"Alopecia areata ": 508.9692650940183, "Drug-induced liver injury ": 41.10149991505892, "Hepatic function abnormal ": 20.77731600369258, "Pancytopenia ": 10.366808009349796, "Urticaria ": 3.071350674460613}
\ No newline at end of file
+{"Abdominal distension": 4.050580729989552, "Alanine aminotransferase increased": 3.1516736017069285, "Ascites": 15.496527183662744, "Aspartate aminotransferase abnormal": 79.22118340654633, "Aspartate aminotransferase increased": 3.3833438359343453, "Blood albumin decreased": 17.153475142848897, "Blood alkaline phosphatase abnormal": 653.362880489703, "Blood alkaline phosphatase increased": 26.190048824191013, "Blood bilirubin abnormal": 88.7207386379766, "Blood bilirubin increased": 30.106597693477987, "Child-Pugh-Turcotte score increased": 872.0945336558773, "Cholelithiasis": 3.0490047592324063, "Cholestasis": 3.2684359384226678, "Chromaturia": 5.281365597074943, "Constipation": 2.6220960114471024, "Death": 3.987673864796167, "Disease progression": 2.9189590813590782, "Encephalopathy": 2.0511740424404508, "Fall": 2.2555033845235517, "Fluid retention": 2.225937888796746, "Gamma-glutamyltransferase abnormal": 239.1050901814988, "Gamma-glutamyltransferase increased": 6.577725107121158, "Hepatic cirrhosis": 44.77995960243233, "Hepatic encephalopathy": 12.694429734823943, "Hepatic enzyme increased": 2.8243513908082805, "Hepatic failure": 27.502509529277027, "Hepatic fibrosis": 79.48418554905066, "Hepatocellular carcinoma": 2.697551802508707, "Hepatomegaly": 5.031470260330458, "Hip fracture": 4.097836635741317, "Hospitalisation": 4.310960522177585, "Hyperbilirubinaemia": 7.373711556774623, "Insurance issue": 28.186777059639294, "Jaundice": 11.290404913775614, "Laboratory test abnormal": 11.790712629326505, "Liver disorder": 2.315184593772416, "Liver function test increased": 4.70692040957297, "Liver transplant": 62.27696103920935, "Model for end stage liver disease score increased": 3834.7455166239465, "Nervousness": 2.500585402662928, "No adverse event": 4.274842085440388, "Ocular icterus": 16.88078745165721, "Oedema peripheral": 2.6813077842719006, "Oesophageal varices haemorrhage": 39.952015691301774, "Oral pain": 3.645594118980828, "Portal hypertension": 23.18355387462372, "Primary biliary cholangitis": 131.2628631456531, "Product dose omission issue": 4.929712691411372, "Product prescribing error": 15.9354432815253, "Pruritus": 13.145515317585742, "Skin haemorrhage": 12.10929645087012, "Skin lesion": 2.2192977404845484, "Splenomegaly": 6.826762285652174, "Surgery": 3.3667616356496044, "Therapy interrupted": 57.92968715427239, "Transaminases increased": 2.723856327905716, "Treatment noncompliance": 3.8220451455064, "Urinary tract infection": 2.3210663771414404, "Varices oesophageal": 24.7514758920342, "Viral infection": 2.96029910183373, "Yellow skin": 10.414216359918186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/798.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/798.json
index 66d1b95c7ae..98039a1cda5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/798.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/798.json
@@ -1 +1 @@
-{"Herpes zoster ": 6.555151153543076}
\ No newline at end of file
+{"Abdominal pain": 4.280217286548042, "Anal incontinence": 143.4849730525466, "Arthropathy": 17.62765613959282, "Back pain": 6.007984708625272, "Bacterial disease carrier": 1932.5772961263, "Bronchiectasis": 179.1479124851229, "Carpal tunnel syndrome": 134.7226658250234, "Chronic respiratory failure": 1247.990565363114, "Decubitus ulcer": 276.19978532385227, "Depression": 6.944386209982682, "Dysphagia": 14.487076422584666, "Enterobacter infection": 1176.461061785761, "Hypertonia": 158.83610522990733, "Hypoaesthesia": 6.216929041966256, "Hypothyroidism": 23.937833835471064, "Hypoxia": 36.494907587940936, "Implant site erosion": 4167.916707069352, "Lymphoedema": 171.59470648540855, "Muscle spasms": 8.975409337745328, "Muscular weakness": 10.242025034482634, "Neck pain": 15.72842707541396, "Nerve compression": 283.4974384664607, "Neurogenic bladder": 768.5327563352045, "Neuropathy peripheral": 14.3309623947519, "Osteonecrosis": 11.797922540172449, "Pneumonia aspiration": 61.49413817699495, "Repetitive strain injury": 10922.780900207154, "Therapeutic response unexpected": 48.33567229941479, "Urinary tract infection bacterial": 694.9936888732852}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/799.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/799.json
index 635a946f27d..ad968f167bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/799.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/799.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 8.180619852071928, "Alanine aminotransferase increased ": 2.2722500177165923, "Anaemia ": 4.7249467804610585, "Anuria ": 3.2301788820576784, "Ascites ": 11.281419352584866, "Aspartate aminotransferase increased ": 2.670807948973907, "Blood albumin decreased ": 9.268549993358006, "Blood alkaline phosphatase increased ": 2.070767466038057, "Blood bilirubin abnormal ": 54.23594779242484, "Blood bilirubin increased ": 31.52470415886541, "Cheilitis ": 17.171008689501928, "Dermatitis bullous ": 4.730784363599918, "Drug ineffective ": 6.509786942443665, "Eczema ": 2.2986677950224768, "Encephalopathy ": 3.251525412656104, "Haemoglobin decreased ": 3.2054666526803826, "Hepatic cancer ": 5.621424277234415, "Hepatic cirrhosis ": 12.51313699003402, "Hepatic encephalopathy ": 20.83149632821512, "Hepatic failure ": 18.711822179841597, "Hepatic function abnormal ": 2.22619695749173, "Hepatic lesion ": 8.933914118091076, "Hepatitis C ": 119.83930948018384, "Hepatitis C RNA ": 530.1486413459464, "Hepatitis C RNA increased ": 68.92528886197735, "Hepatitis C virus test positive ": 43.4134411319507, "Hepatitis acute ": 4.657834937980569, "Hepatocellular carcinoma ": 20.56345777099131, "Hepatorenal syndrome ": 50.17000056017976, "Hyperbilirubinaemia ": 61.468550347275226, "Irritability ": 2.3920423296030413, "Jaundice ": 14.887130439995582, "Lip oedema ": 3.1115354828713917, "Liver transplant ": 19.22634199254209, "Lung adenocarcinoma ": 28.043911661689865, "Lymphopenia ": 4.572777251010968, "Multiple organ dysfunction syndrome ": 2.102722631470594, "Off label use ": 9.880882689573005, "Photosensitivity reaction ": 61.43671189451053, "Portal vein thrombosis ": 16.432735008781343, "Product quality issue ": 13.823559289434725, "Pruritus ": 2.428640077078519, "Sinus bradycardia ": 7.737885858959147, "Skin exfoliation ": 2.2929879370282253, "Solar dermatitis ": 83.46544440553645, "Sudden death ": 5.140131934387264, "Sunburn ": 74.22520496059998, "Therapy non-responder ": 2.743193873313693, "Toxic skin eruption ": 4.347186937978319, "Transaminases increased ": 4.391375733580238, "Transplant rejection ": 10.127033979340144, "Treatment failure ": 8.773391275663554, "Treatment noncompliance ": 2.5238475424439133, "Viral load increased ": 40.2837904915344, "Viral mutation identified ": 12.719277201096364, "Virologic failure ": 12.010557119057042, "White blood cell count increased ": 2.056386271795356}
\ No newline at end of file
+{"Abdominal pain upper": 2.464782315465361, "Back pain": 2.1958114803796662, "Body temperature": 11.43765595591051, "Brain fog": 2.921247072799072, "Cardiac flutter": 2.1716398788838114, "Chills": 3.707182119028945, "Cluster headache": 5.214815332736182, "Cold sweat": 2.630172260974184, "Dizziness": 2.66812112548572, "Dizziness postural": 8.774033439835945, "Dry throat": 2.178238103265466, "Ear pain": 3.648087269378721, "Eye pain": 3.298709203934587, "Facial pain": 2.1275370874352078, "Fatigue": 2.66815856145784, "Feeling cold": 4.244807473350331, "Feeling jittery": 2.538808805793816, "Feeling of body temperature change": 3.657937578654438, "Headache": 3.11686111249739, "Heart rate": 19.30133170341808, "Heavy menstrual bleeding": 2.643238479242716, "Hot flush": 2.473242295498163, "Hyperhidrosis": 3.077071142384776, "Hypersomnia": 2.1322792122852228, "Hypoaesthesia": 2.2435269037692445, "Hypopnoea": 3.103791315509961, "Illness": 4.450875011609018, "Influenza": 2.7426369016558434, "Influenza like illness": 2.081867476320613, "Infusion related reaction": 4.998457308163618, "Injection site mass": 6.773426722133022, "Injection site rash": 2.126582014570768, "Lethargy": 2.8545789173575917, "Lymphocyte count decreased": 2.554693708509088, "Menstruation delayed": 2.4347790216555563, "Mental fatigue": 7.616292890702161, "Migraine": 5.484802571288236, "Migraine with aura": 3.3764880255750924, "Multiple sclerosis": 3.401730020793124, "Muscle fatigue": 7.347258373151082, "Muscle spasms": 2.414184311075216, "Nausea": 2.2684913626526373, "Neck pain": 2.455179981212995, "Night sweats": 4.153147057131456, "Oropharyngeal pain": 3.431002205538752, "Osteitis": 14.060918278305577, "Pain": 2.1148919942854496, "Pain in extremity": 3.0998090747546483, "Pain of skin": 2.25049530595799, "Periarthritis": 3.848160186375156, "Peripheral coldness": 2.360016978279293, "Peripheral swelling": 2.2323481878442077, "Peroneal nerve palsy": 7.332546810017771, "Poor quality sleep": 3.051282766372598, "Pyrexia": 2.699632728805464, "Renal pain": 2.877842697758765, "Restless legs syndrome": 2.3147052682139906, "Sensitive skin": 3.63719829816344, "Sinus headache": 13.080153510882118, "Sinus pain": 7.737994939387002, "Skin warm": 3.994068374846879, "Sweating fever": 20.01630453276819, "Tenderness": 2.508620157370585, "Tension headache": 6.2573695679210894, "Thirst": 4.193062384398799, "Tinnitus": 2.042442965573819, "Tooth disorder": 2.2194948584385994, "Tremor": 2.4068687955683665, "Vaccination site mass": 5.056320971328449}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/8.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/8.json
index 967fb08034c..a6ee913cdf4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/8.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/8.json
@@ -1 +1 @@
-{"Acute coronary syndrome ": 98.12491820156411, "Acute kidney injury ": 7.839449914233081, "Disease progression ": 19.19293996840077, "Drug interaction ": 2.729721991634752, "Hepatotoxicity ": 27.09826907391346, "Hormone-refractory prostate cancer ": 497.7202871067497, "Hypokalaemia ": 9.00798235062046, "Malignant neoplasm progression ": 9.80531146295762, "Prostate cancer metastatic ": 758.3802573695656, "Rhabdomyolysis ": 27.94208360278053}
\ No newline at end of file
+{"Abnormal behaviour": 3.673334873313861, "Abnormal weight gain": 3.654288968139205, "Accident": 3.7223706498328295, "Accommodation disorder": 4.315958784874212, "Adverse drug reaction": 3.5330031053492226, "Affective disorder": 3.1261983616183264, "Aggression": 7.278328635002231, "Agitation": 3.3478395745522658, "Akathisia": 58.8531046935702, "Alcoholism": 7.524988673457317, "Allergy to animal": 7.59322655372163, "Amphetamines positive": 19.96714608383073, "Analgesic drug level above therapeutic": 268.98576278857007, "Anger": 4.135706842858733, "Anorgasmia": 6.919282397095749, "Anosognosia": 811.2855474573316, "Antidepressant drug level above therapeutic": 66.58510370857897, "Antipsychotic drug level below therapeutic": 237.3728251579793, "Antipsychotic drug level increased": 3.857990757426293, "Anxiety": 2.3211456624946027, "Anxiety disorder": 9.06751849484344, "Apathy": 5.272929246421821, "Atrophy": 24.34659861730957, "Attention deficit hyperactivity disorder": 2.0700574810024293, "Behaviour disorder": 2.119468220105331, "Binge eating": 14.405047208956498, "Bipolar I disorder": 5.578219738762844, "Bipolar disorder": 15.755162315642222, "Blood bicarbonate decreased": 9.099732145690057, "Blood creatine phosphokinase increased": 2.9995710762154264, "Blood creatinine decreased": 4.441179664850091, "Blood glucose increased": 2.7654011047652136, "Blood prolactin abnormal": 1363.272487165775, "Blood prolactin increased": 11.711487498815028, "Blood triglycerides increased": 2.60263365811968, "Body temperature abnormal": 2.295687722819652, "Body temperature decreased": 2.4339677329117886, "Borderline personality disorder": 14.736889052495949, "Botulism": 64.06297781425855, "Bradykinesia": 2.263913939166156, "Bradyphrenia": 2.2566564083035496, "Breech presentation": 79.93635371845598, "Bruxism": 6.645779060586535, "Bundle branch block right": 2.436652751439532, "Caesarean section": 9.976358880353578, "Calcium ionised decreased": 83.30602743376365, "Catatonia": 3.993527230526319, "Cleft lip and palate": 5.810207125388753, "Cogwheel rigidity": 4.785735173208033, "Coma": 2.0717396904327865, "Communication disorder": 2.0619553193761564, "Compulsive sexual behaviour": 66.09061069008744, "Compulsive shopping": 56.89563454034301, "Concussion": 3.608355271074654, "Contrast media allergy": 7.966214721580478, "Decreased interest": 3.9443414333923887, "Delusion": 8.46235153356082, "Delusional disorder, persecutory type": 152.39732773196494, "Depressed level of consciousness": 2.1976764349569566, "Depression": 2.8074729208309277, "Depressive symptom": 3.244875834775766, "Derealisation": 2.7874276351386, "Diabetes mellitus": 7.156910686853711, "Dialysis": 4.600576611317821, "Disability": 2.2388537617035595, "Disease recurrence": 2.335310974678314, "Disinhibition": 137.949182172577, "Disturbance in social behaviour": 203.2598417383264, "Drooling": 3.255378710731277, "Drug effective for unapproved indication": 4.499781009604421, "Drug interaction": 2.653984622018396, "Drug withdrawal syndrome neonatal": 5.642693544756414, "Dry eye": 2.770251697501581, "Dust allergy": 4.108262861012761, "Dyskinesia": 15.683936610897296, "Dyskinesia neonatal": 78.71990194005416, "Dyslipidaemia": 40.75733576697601, "Dystonia": 39.15235187709575, "Eating disorder": 3.207800594176771, "Electrocardiogram QT prolonged": 3.5148395625709266, "Emotional disorder": 4.2377895467052085, "Emotional poverty": 5.321498001344082, "Enuresis": 3.2170994231650707, "Euphoric mood": 43.02828312291222, "Exposure via breast milk": 3.3094446586538617, "Extrapyramidal disorder": 16.595862484815655, "Fear": 2.455779454870995, "Feeling guilty": 10.537810117099314, "Feeling of despair": 4.052039841038141, "Flank pain": 5.121167666456209, "Flat affect": 5.288483529394699, "Foetal distress syndrome": 13.225293047437852, "Foetal exposure during pregnancy": 3.3975274656218546, "Foetal growth restriction": 3.256793325174259, "Foetal heart rate decreased": 8.861841124423377, "Food craving": 4.165696248454848, "Galactorrhoea": 7.4604094540903025, "Gambling disorder": 26.894774191108105, "Gestational diabetes": 14.368150281486573, "Gestational hypertension": 24.283716257423404, "Glucose tolerance impaired": 4.606368789970698, "Gynaecomastia": 5.553865372400018, "Haemangioma": 3.313361887584079, "Haematocrit decreased": 2.486087707626516, "Hallucination, auditory": 15.503110004087238, "Hallucination, visual": 2.3294480562906466, "Hallucinations, mixed": 43.50966740688547, "Homicidal ideation": 4.970505984353743, "Humidity intolerance": 86.90837503679627, "Hunger": 2.829307817880865, "Hyperphagia": 5.829038562087598, "Hyperprolactinaemia": 10.573632723244025, "Hypersomnia": 2.048806572874485, "Hypertension": 2.604304732376006, "Hyperthermia": 2.4085860005435054, "Hypoaesthesia eye": 197.14982519653017, "Hypoglycaemia neonatal": 7.041810677914607, "Hypomania": 3.695679976185136, "Hypothermia": 2.726087495545264, "Hypothyroidism": 4.172755177207447, "Hypoxic-ischaemic encephalopathy": 10.15134321552979, "Impatience": 22.860830801950087, "Impulse-control disorder": 16.74170240924194, "Impulsive behaviour": 12.266971286682733, "Inability to afford medication": 8.925122740638542, "Inappropriate schedule of product administration": 2.336709011145053, "Increased appetite": 33.0992703629578, "Infarction": 6.192199923987996, "Infertility": 10.178780903240384, "Insomnia": 2.2221926829983127, "Insurance issue": 35.78589316191043, "Intentional overdose": 3.770383544607679, "Intentional self-injury": 5.961659895892341, "International normalised ratio abnormal": 6.726556888253144, "Intestinal obstruction": 2.3357864216059583, "Intrusive thoughts": 14.918731891158965, "Irritability": 6.643878975327891, "Jaundice neonatal": 16.494457985737277, "Joint effusion": 5.746260228558585, "Large for dates baby": 12.72705516851472, "Left ventricular dysfunction": 5.327319686394221, "Leukaemia": 32.40651090492601, "Leukopenia": 4.380137926039308, "Libido decreased": 2.9021596558488967, "Libido increased": 4.702537593036408, "Ligament sprain": 3.307190540085396, "Live birth": 7.833685051182968, "Loss of employment": 4.88638113707603, "Loss of libido": 4.211853418058283, "Major depression": 4.745339845794723, "Mania": 11.539308753896876, "Mastication disorder": 5.237408506474144, "Maternal exposure during pregnancy": 3.871931466317655, "Memory impairment": 3.132792460533706, "Menopause": 4.852736196406471, "Mental disorder": 4.88355343032586, "Mental impairment": 3.037660062574904, "Metabolic disorder": 83.10786137233795, "Metabolic syndrome": 29.53343900548627, "Milk allergy": 10.850711345683438, "Mixed liver injury": 3.63201977734721, "Mood altered": 2.9531634330031737, "Muscle contracture": 3.153394120556986, "Muscle disorder": 2.9456177657334197, "Muscle rigidity": 4.700718668441071, "Mutism": 6.846735747650685, "Mycotic allergy": 4.904933880468693, "Mydriasis": 2.3586005229799603, "Myofascial pain syndrome": 47.27087011475746, "Negative thoughts": 3.761392548046301, "Neonatal respiratory distress": 18.536098205789894, "Neonatal respiratory distress syndrome": 4.267652956475717, "Neuroleptic malignant syndrome": 15.218072004490958, "Normal newborn": 6.232757513569969, "Obesity": 33.16537302849077, "Obsessive-compulsive disorder": 73.14962168574883, "Oculogyric crisis": 28.59089182223291, "Ophthalmoplegia": 3.654096292351168, "Oropharyngeal discomfort": 7.230771245720175, "Orthostatic hypertension": 111.30641883025262, "Overdose": 2.332464621296744, "Panic disorder": 2.139114101318896, "Panic reaction": 8.74408217567114, "Paranoia": 3.605108055435795, "Parkinson's disease": 2.605071039840537, "Parkinsonism": 18.55459376855225, "Patient elopement": 19.16623029155675, "Perinatal depression": 30.648967397128345, "Persecutory delusion": 4.395464191973228, "Persistent depressive disorder": 11.218819192979408, "Personal relationship issue": 12.03033426106392, "Personality change": 36.74182942947217, "Personality change due to a general medical condition": 127.67347794842408, "Personality disorder": 8.344420169633269, "Piloerection": 6.715642544640618, "Pleurothotonus": 11.002662062773094, "Pneumonia aspiration": 2.2516726750508904, "Poisoning deliberate": 2.919948139145589, "Polyuria": 3.543843943012655, "Poor feeding infant": 5.570862388032117, "Post-traumatic stress disorder": 2.395722096780584, "Posture abnormal": 10.401753743678224, "Potentiating drug interaction": 2.3660904453565577, "Pregnancy": 4.788943680869141, "Premature baby": 6.544793346684963, "Premature delivery": 6.638622917125344, "Premature labour": 3.40722504167456, "Prescribed overdose": 14.963308792199156, "Prescribed underdose": 6.376538326555682, "Product dose omission issue": 2.210449056824037, "Product use in unapproved indication": 5.029988914072413, "Psychiatric decompensation": 9.609835919802954, "Psychiatric symptom": 5.61354257059456, "Psychomotor hyperactivity": 4.155866645617641, "Psychomotor retardation": 4.694678166947435, "Psychomotor skills impaired": 4.580325375712034, "Psychotic disorder": 17.881137443856215, "Psychotic symptom": 32.82079170847895, "Refusal of treatment by patient": 10.88302855754626, "Restless legs syndrome": 2.921978349099547, "Restlessness": 4.188663766654194, "Rhabdomyolysis": 2.3289161958441773, "Rhesus incompatibility": 2169.1921145904967, "Rubber sensitivity": 10.022344975172466, "Salivary hypersecretion": 4.658463036717731, "Schizoaffective disorder": 86.45314892553935, "Schizophrenia": 47.51730364406918, "Schizophreniform disorder": 25.36363654563196, "Screaming": 2.1564542404636526, "Sedation": 25.48518799739108, "Self-destructive behaviour": 6.789115383444483, "Self-injurious ideation": 2.7090519438833733, "Sepsis neonatal": 18.336984555910984, "Serotonin syndrome": 3.056094891446715, "Sexual dysfunction": 53.17091304442415, "Social anxiety disorder": 8.340877861119433, "Social avoidant behaviour": 15.41781469781076, "Social fear": 47.87742560728553, "Somatic symptom disorder": 18.36497837226428, "Sopor": 4.069804954999277, "Staphylococcal infection": 7.899665824778323, "Status epilepticus": 2.3618785553841994, "Stubbornness": 111.69325845879636, "Stupor": 2.7585123646326166, "Substance abuse": 3.5243071577217524, "Substance use": 287.56873454484, "Substance-induced psychotic disorder": 21.302382393684244, "Sudden cardiac death": 6.057748536867237, "Suicidal behaviour": 2.456375200920393, "Suicidal ideation": 4.8353374674871965, "Suicide attempt": 15.286550266862092, "Symptom recurrence": 14.377981536510662, "Tachyphrenia": 5.413327830099603, "Tardive dyskinesia": 26.23340159079271, "Tension": 2.223020479483047, "Therapeutic product effect incomplete": 6.058721021609807, "Therapeutic product effect variable": 163.73466877154402, "Therapy cessation": 4.838594741499675, "Therapy change": 3.111395532765401, "Therapy non-responder": 2.291972037666685, "Thermal burn": 34.15946837796519, "Thinking abnormal": 6.094783991067126, "Throat tightness": 3.337973022224559, "Tic": 6.4323536560976216, "Toxicity to various agents": 4.514966634703039, "Transfusion": 3.2791463799900336, "Transient tachypnoea of the newborn": 47.00805777255162, "Treatment noncompliance": 7.77534362298978, "Tremor": 2.116342228729783, "Type 2 diabetes mellitus": 2.075872705993881, "Underdose": 2.757229938531461, "Unemployment": 52.97255007445774, "Urinary hesitation": 4.542384743242111, "Ventricular arrhythmia": 2.1231097998404977, "Violence-related symptom": 6.048001234188121, "Weight fluctuation": 5.697540464440333, "Weight increased": 9.85267080888011, "Wound": 5.413631529546075, "Wound complication": 30.33072418841629, "Wrong technique in product usage process": 3.387649586282831}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/80.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/80.json
index 1be96b0252d..d9e281f06ef 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/80.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/80.json
@@ -1 +1 @@
-{"Acute kidney injury ": 3.6412271830490575, "Anaemia ": 2.371752324636192, "Bacteraemia ": 27.023867156305663, "Bronchopulmonary aspergillosis ": 62.51483531482919, "COVID-19 pneumonia ": 38.77825477129275, "Candida infection ": 44.95447980235934, "Cellulitis ": 6.978286938413132, "Condition aggravated ": 7.618217268206459, "Drug ineffective ": 3.271138709902172, "Drug resistance ": 32.48423929122619, "Eye infection fungal ": 1305.0195962222592, "Haemodynamic instability ": 68.80844849758704, "Intraocular pressure test ": 1512.9765152147052, "Intraocular pressure test abnormal ": 697.7867588970669, "Klebsiella infection ": 74.67587544324111, "Multi-organ disorder ": 149.71178760117215, "Multiple organ dysfunction syndrome ": 32.04139621301433, "Neutropenia ": 8.283197941217677, "Pancytopenia ": 3.9428006652885976, "Pathogen resistance ": 41.06116395601374, "Peritonitis ": 33.843766951424854, "Renal impairment ": 3.5051184866331315, "Respiratory failure ": 4.206649519313346, "Scedosporium infection ": 1236.0227957260513, "Sepsis ": 7.635830207299897, "Septic shock ": 22.45631767990235, "Thrombocytopenia ": 2.7263637091714057}
\ No newline at end of file
+{"Acute myocardial infarction": 9.35550442101695, "Bradycardia": 3.232926801355928, "Cardiac arrest": 12.874130494253755, "Cardiac failure": 2.4775882900395065, "Cardiac tamponade": 99.2925357550834, "Cardio-respiratory arrest": 9.684193719005332, "Cardiogenic shock": 21.47309423000936, "Cerebral haemorrhage": 6.251988302359264, "Chest pain": 2.0049694070971675, "Coagulation time abnormal": 6112.261523717118, "Coagulopathy": 20.283819701341173, "Coronary artery dissection": 1089.2542757072365, "Coronary artery occlusion": 37.35231260250416, "Coronary artery perforation": 7196.372120109358, "Coronary artery thrombosis": 731.2447008081293, "Death": 2.177920083353408, "Device occlusion": 152.72878465706273, "Device related thrombosis": 252.83703855717584, "Haematoma": 7.602528803716543, "Haemoglobin decreased": 5.936204469293225, "Haemorrhage": 9.510545799059694, "Haemorrhage intracranial": 30.169453963045854, "Hypotension": 3.675187308095426, "International normalised ratio increased": 11.86043449487409, "Myocardial infarction": 4.128972686019072, "Off label use": 2.2153288858824287, "Overdose": 2.990223381675826, "Platelet count decreased": 2.9170750797567284, "Post procedural haemorrhage": 34.2588339284578, "Pulmonary haemorrhage": 62.2819798164794, "Puncture site haemorrhage": 603.795835892118, "Reperfusion injury": 2923.133191845433, "Respiratory arrest": 10.383147837131364, "Respiratory failure": 4.717831041274878, "Thrombocytopenia": 3.43998358040071, "Thrombosis": 15.06689162095558, "Thrombosis in device": 1411.7258483360908, "Vascular stent thrombosis": 89.51621675808734, "Ventricular fibrillation": 28.014567990503814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/800.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/800.json
index 0feeb9c4621..90c707ad451 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/800.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/800.json
@@ -1 +1 @@
-{"Accident ": 3.056239258440144, "Allergy to animal ": 59.334493209915, "Allergy to chemicals ": 28.60604262039675, "Allergy to metals ": 10.359655157342216, "Allergy to plants ": 169.27800812603675, "Alpha 1 globulin increased ": 120.3782051321448, "Alpha 2 globulin increased ": 120.3782051321448, "Alveolar osteitis ": 318.7836480658726, "Anaphylactic reaction ": 2.5126463308115072, "Aneurysm ": 4.402838179403826, "Angioedema ": 2.38977781356213, "Animal scratch ": 185.6870593965517, "Aortic aneurysm ": 5.654030358498327, "Aphonia ": 3.3723739464537097, "Arthropod bite ": 4.1974747059302215, "Asthma ": 20.348422047350333, "Asthmatic crisis ": 3.3839733280445805, "Basophil percentage decreased ": 196.94243336374657, "Biliary colic ": 4.819398578611437, "Bladder pain ": 18.334293330578927, "Blood immunoglobulin E increased ": 30.152529532280926, "Blood iron decreased ": 18.139878914935984, "Blood pressure diastolic decreased ": 7.144644246218551, "Blood pressure diastolic increased ": 6.992976739592857, "Blood pressure increased ": 4.021068855045272, "Blood pressure systolic increased ": 31.539085377525303, "Blood test abnormal ": 3.872188813681152, "Blood urine present ": 4.195451152866994, "Body temperature decreased ": 24.374644575433223, "Breath sounds abnormal ": 7.964970962215161, "Bronchial obstruction ": 7.328313837359365, "Bronchial secretion retention ": 8.745385729991323, "Bronchiectasis ": 12.98511763686602, "Bronchitis ": 9.035773133460706, "Bronchopulmonary aspergillosis allergic ": 59.39389636963968, "Burning sensation ": 2.659814329413694, "Caffeine allergy ": 348.7282203355524, "Calculus urinary ": 19.933529875740696, "Carpal tunnel syndrome ": 2.730412040789913, "Cellulitis ": 2.870984802543717, "Central pain syndrome ": 38.997590582471325, "Chest discomfort ": 3.2779812215098, "Choking ": 3.289418995894397, "Choking sensation ": 2.9024203933604884, "Chronic obstructive pulmonary disease ": 3.066744377771093, "Chronic sinusitis ": 2.447115872651612, "Chronic spontaneous urticaria ": 25.722699476147245, "Cold agglutinins positive ": 120.3782051321448, "Complex regional pain syndrome ": 4.396430152421476, "Concomitant disease aggravated ": 4.1753263394866265, "Cough ": 6.020867547351116, "Crepitations ": 3.4672233002103416, "Cryopyrin associated periodic syndrome ": 166.34731400122325, "Dermatitis contact ": 12.253354919744678, "Dermoid cyst ": 42.588776709148654, "Drug hypersensitivity ": 12.101184423592176, "Dry throat ": 2.7475552889001618, "Dust allergy ": 33.6791259042143, "Dyslipidaemia ": 2.05477291599519, "Dysphonia ": 2.5908484895114263, "Dyspnoea ": 3.0598063612749207, "Dyspnoea at rest ": 7.884223483013757, "Dyspnoea exertional ": 5.341831501654936, "Ear congestion ": 13.276737289082073, "Ear discomfort ": 2.828427380011585, "Ear infection ": 5.443222600442429, "Ear swelling ": 5.614680047079582, "Eosinophil count increased ": 10.152866744461052, "Eosinophilic granulomatosis with polyangiitis ": 8.365093057384868, "Exposure to allergen ": 134.88905424791486, "Eye contusion ": 5.905642435805313, "Eye discharge ": 7.523068777922456, "Eye pruritus ": 2.484991595782415, "Eye swelling ": 2.5478540952952824, "FEV1/FVC ratio decreased ": 270.0282804360942, "Fear of injection ": 6.058836619874021, "Food allergy ": 11.280232486026078, "Forced expiratory volume decreased ": 158.16842441219603, "Forced vital capacity abnormal ": 287.485391582833, "Forced vital capacity decreased ": 45.86172568126258, "Foreign body sensation in eyes ": 5.035664043668312, "Frustration tolerance decreased ": 10.279502156514525, "Full blood count abnormal ": 7.521377292703174, "Gastroenteritis viral ": 3.706093995091312, "General physical condition abnormal ": 5.327959102795035, "Giant cell arteritis ": 3.940532271061426, "Heart rate decreased ": 2.474138362896178, "Heart rate increased ": 3.556100551072816, "Hormone level abnormal ": 3.6160473735633847, "Humidity intolerance ": 91.6764137515006, "Hypophagia ": 2.0114990444954444, "Hyposmia ": 5.218626617594258, "Hypoventilation ": 26.953863335182177, "Illness ": 3.2337496212121875, "Immune system disorder ": 2.5672974508663997, "Inappropriate schedule of product administration ": 3.4153061409529117, "Incorrect dose administered ": 2.112311293662732, "Increased bronchial secretion ": 8.76056365018181, "Increased upper airway secretion ": 4.437324169530553, "Influenza ": 2.817614568065777, "Injection site bruising ": 6.12299501848918, "Injection site haemorrhage ": 2.417497171054172, "Joint dislocation ": 4.119786123383254, "Lacrimation increased ": 2.08615339088857, "Laryngitis ": 4.808069788968769, "Ligament rupture ": 9.482026379166994, "Ligament sprain ": 7.911694007255219, "Loss of personal independence in daily activities ": 2.7422822870531185, "Lower respiratory tract infection ": 6.16530331518118, "Lung consolidation ": 8.00091386457747, "Lung diffusion test decreased ": 61.35249931651309, "Lung disorder ": 4.268430244772706, "Lymphocyte percentage decreased ": 10.779133786317669, "Mast cell activation syndrome ": 7.42692119857508, "Mastocytosis ": 24.92111361971912, "Mechanical urticaria ": 4.674798296271496, "Middle insomnia ": 25.712367272315667, "Mobility decreased ": 2.0526565769129284, "Monocyte percentage increased ": 35.516110586954184, "Multiple allergies ": 6.431103832172015, "Myopathy ": 3.2253458972389915, "Nasal congestion ": 7.723498960965423, "Nasal discharge discolouration ": 56.705455127876206, "Nasal oedema ": 63.805634159832906, "Nasal polyps ": 15.993468344541697, "Nasopharyngitis ": 5.157104851191668, "Nerve compression ": 6.084195779428255, "Normal newborn ": 2.9101533306861342, "Obstructive airways disorder ": 23.182360764463414, "Oedema ": 9.524840635649024, "Oropharyngeal pain ": 2.697550249608793, "Oxygen saturation decreased ": 2.2725482753591963, "Papule ": 2.2521682669237126, "Peak expiratory flow rate decreased ": 10.768901053867998, "Perfume sensitivity ": 182.6881870036343, "Pharyngeal paraesthesia ": 3.105734476934358, "Pneumonia ": 4.848616122470374, "Post procedural complication ": 3.278814282345127, "Product availability issue ": 2.810760376612675, "Productive cough ": 14.520690253880655, "Pulmonary congestion ": 2.3897913851600987, "Pulmonary function test decreased ": 7.83653574971045, "Pulmonary thrombosis ": 6.218314566471951, "Pyelonephritis ": 2.136523295454161, "Quality of life decreased ": 2.653036056217251, "Renal neoplasm ": 13.810943766533995, "Respiration abnormal ": 2.9662403606150654, "Respiratory disorder ": 3.536565114041612, "Respiratory rate decreased ": 4.997827755906314, "Respiratory rate increased ": 7.518790513776855, "Respiratory tract congestion ": 20.169682576198927, "Respiratory tract infection ": 21.58096657896734, "Respiratory tract infection fungal ": 27.6704034917253, "Restrictive pulmonary disease ": 12.29904324609998, "Rhinorrhoea ": 3.647646075692884, "Rubber sensitivity ": 67.94600535346616, "Scratch ": 11.26370358883795, "Seasonal allergy ": 9.120068804313505, "Secretion discharge ": 8.034700169657185, "Sensitivity to weather change ": 69.57827674274456, "Sinus congestion ": 6.591708898377648, "Sinus disorder ": 5.591133500570365, "Sinus pain ": 2.1685926245694995, "Sinusitis ": 6.78077165200097, "Skin atrophy ": 4.5025123963563685, "Skin fragility ": 20.834120037371957, "Skin haemorrhage ": 2.0351153344175783, "Skin plaque ": 13.453362506336688, "Sleep disorder due to a general medical condition ": 6.094867262924109, "Smoke sensitivity ": 158.71231093760247, "Sneezing ": 2.276062165974288, "Spinal disorder ": 2.7783891928047044, "Spinal fusion surgery ": 8.48743125488445, "Spirometry abnormal ": 64.87998153114833, "Sputum discoloured ": 52.83208032032173, "Staphylococcus test positive ": 21.07837394453258, "Stress ": 4.224858086692782, "Superior mesenteric artery syndrome ": 76.96150695666543, "Temperature intolerance ": 2.9747576488066234, "Therapeutic product effect incomplete ": 2.4279944772029403, "Therapeutic response decreased ": 3.8019431678204407, "Therapeutic response shortened ": 2.66209341203168, "Therapy partial responder ": 2.878688078511013, "Throat clearing ": 29.01714202930412, "Throat tightness ": 2.136943316380054, "Total lung capacity increased ": 29.52169392153544, "Type 2 diabetes mellitus ": 2.241540216248345, "Upper respiratory tract infection ": 3.777376695465296, "Upper-airway cough syndrome ": 4.975918776647061, "Urticaria ": 3.73499466183055, "Urticarial vasculitis ": 8.947273126012538, "Uterine cancer ": 4.719952741127392, "Weight decreased ": 2.077244427797216, "Weight increased ": 2.1938580442359483, "Wheezing ": 20.961389587881644}
\ No newline at end of file
+{"Fall": 3.270991038097304, "Gait disturbance": 3.484898446563724, "Intentional product use issue": 7.445990178470172, "Multiple sclerosis": 38.058270279091005, "Multiple sclerosis relapse": 29.09856964033237}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/801.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/801.json
index ceb54aa3cb0..51bbf9e0b0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/801.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/801.json
@@ -1 +1 @@
-{"Device breakage ": 96.78804880737115, "Device issue ": 94.3523044656571, "Device malfunction ": 17.31809282196066, "Device occlusion ": 52.455892848644005, "Growth retardation ": 106.84320022944836, "Incorrect dose administered ": 17.005229286481775, "Incorrect dose administered by device ": 80.89170409175007, "Injection site bruising ": 14.132800957583653, "Injection site haemorrhage ": 21.70108096101536, "Injection site pain ": 4.978477429703687, "Intracranial pressure increased ": 36.37607540367611, "Papilloedema ": 46.948165393100005, "Product dose omission issue ": 6.3097328956006296, "Product quality issue ": 10.19779197379122, "Product storage error ": 18.184002506667014, "Scoliosis ": 42.924190453972365, "Wrong technique in product usage process ": 9.245741986126196}
\ No newline at end of file
+{"Anti factor VIII antibody positive": 4529.024532274634, "Drug ineffective": 7.684157762904099, "Factor VIII inhibition": 1707.5779513017712}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/802.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/802.json
index f72cc2b80fd..c0e2f15904a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/802.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/802.json
@@ -1 +1 @@
-{"Asthma ": 9.563891615487076, "Chronic obstructive pulmonary disease ": 27.054889076649783, "Death ": 4.786606785309365, "Dyspnoea ": 2.595198844348832, "Pneumonia ": 3.3310341862791755, "Product use in unapproved indication ": 4.530251907192977, "Tachycardia ": 4.158076160277644}
\ No newline at end of file
+{"Abdominal distension": 3.718576062726355, "Bone pain": 4.514649864366543, "Cholelithiasis": 19.996518143655745, "Disease progression": 2.839871820071082, "Disseminated intravascular coagulation": 19.71523571605949, "Drug reaction with eosinophilia and systemic symptoms": 7.934345023941725, "Epistaxis": 2.7555047985676877, "Heart rate decreased": 11.257876641843296, "Hyperglycaemia": 6.794022826848816, "Illness": 4.5321324450549, "Malignant neoplasm progression": 6.346768049164015, "Metastases to liver": 19.263468254725467, "Post procedural haemorrhage": 40.42174416181631, "Product use in unapproved indication": 2.309562434134136, "Rectal haemorrhage": 6.984364082233032, "Sepsis": 6.38044491014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/803.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/803.json
index a4a2672f728..3afa09a9c7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/803.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/803.json
@@ -1 +1 @@
-{"Abdominal pain ": 6.083496424532279, "Acute hepatic failure ": 4.943831422580731, "Amylase increased ": 12.987830257816848, "Anaphylactic reaction ": 21.36057766273677, "Anaphylactic shock ": 8.05132336096863, "Angioedema ": 7.957896384667647, "Antithrombin III decreased ": 199.4393686798386, "Ascites ": 4.633524375200259, "Blood bilirubin increased ": 5.677846040567617, "Bronchial obstruction ": 33.35428060941311, "Bronchospasm ": 20.408095103681894, "Cerebral infarction ": 3.2536025978735297, "Cerebral thrombosis ": 21.4923986331292, "Cerebral venous sinus thrombosis ": 24.661065207642363, "Cerebral venous thrombosis ": 33.36910797971484, "Coagulopathy ": 20.76582172902712, "Conjunctival hyperaemia ": 13.5280991503291, "Cough ": 2.913989635616507, "Cyanosis ": 3.650769378524246, "Dermatitis allergic ": 2.3680730845568143, "Disseminated intravascular coagulation ": 3.1381527471154307, "Drug hypersensitivity ": 2.3823726608308453, "Enzyme activity decreased ": 1281.4118526107254, "Erythema ": 4.785636977482769, "Eyelid oedema ": 9.766366263828298, "Face oedema ": 6.828729344336477, "Febrile neutropenia ": 11.620270303241446, "Flushing ": 4.244007194839566, "Hepatic cytolysis ": 2.109524913435433, "Hepatic failure ": 2.808892939856285, "Hepatic steatosis ": 8.173486909472942, "Hepatotoxicity ": 14.902398467486284, "Hyperaemia ": 46.069756471356136, "Hyperammonaemia ": 16.736105301556027, "Hyperbilirubinaemia ": 9.594333350376742, "Hypercholesterolaemia ": 4.941555833393443, "Hyperglycaemia ": 3.013646663986965, "Hyperlipidaemia ": 7.555458285586069, "Hypersensitivity ": 22.4520723404827, "Hypertriglyceridaemia ": 68.31196412915445, "Hypoalbuminaemia ": 22.7291142734394, "Hypofibrinogenaemia ": 136.5486105268739, "Hypotension ": 2.762935522525836, "Hypoxia ": 3.025177610049864, "Infusion related reaction ": 2.140329760239252, "Jugular vein thrombosis ": 38.610380459476936, "Laryngeal oedema ": 10.590741067372392, "Lip oedema ": 17.640166133587712, "Lip swelling ": 9.786860654492523, "Lipase increased ": 15.420887004898502, "Liver disorder ": 2.8780958641495054, "Mental status changes ": 4.106175822646401, "Multiple organ dysfunction syndrome ": 2.4180213598553766, "Oral discomfort ": 3.657221832604946, "Oxygen saturation decreased ": 5.553547877119749, "Pallor ": 4.678060512202109, "Pancreatic pseudocyst ": 91.4197460099163, "Pancreatitis ": 30.006224014559614, "Pancreatitis acute ": 24.737938345639527, "Pancreatitis necrotising ": 142.5177441968473, "Posterior reversible encephalopathy syndrome ": 15.444983639313, "Pruritus ": 2.186971231412792, "Pseudomonal sepsis ": 32.13838074555922, "Rash maculo-papular ": 2.2438521141607817, "Respiratory distress ": 3.8703322688822, "Sepsis ": 2.3274740570783186, "Septic shock ": 3.514681479114153, "Shock ": 6.7401354049871465, "Superior sagittal sinus thrombosis ": 175.0772413754705, "Swelling face ": 3.591286846989186, "Tachycardia ": 2.2196344759705298, "Underdose ": 3.125211649446757, "Urticaria ": 6.837331823009941, "Venoocclusive disease ": 28.06381476138436, "Vomiting ": 3.249583682998379}
\ No newline at end of file
+{"Anaemia": 2.8867400411180806, "Chronic lymphocytic leukaemia": 170.13014330783722, "Diffuse large B-cell lymphoma": 96.02542075337604, "Diffuse large B-cell lymphoma recurrent": 218.4133132089203, "Malignant neoplasm progression": 7.042521180092629, "Neutropenia": 2.618311769296131, "Pneumonia": 2.2505228850080816, "Product use in unapproved indication": 15.181231649075045, "Throat irritation": 12.142701430593592, "Toxicity to various agents": 3.286302126994183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/804.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/804.json
index de31a0c2931..365d63b88b7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/804.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/804.json
@@ -1 +1 @@
-{"Dyskinesia ": 56.53748089743798, "Hallucination ": 24.397770380650236}
\ No newline at end of file
+{"Abdominal discomfort": 2.292965435047865, "Abdominal distension": 2.052415346549608, "Abdominal pain": 2.953012582476298, "Abdominal pain upper": 2.7787216174869185, "Abnormal loss of weight": 9.189783815760324, "Acute coronary syndrome": 4.000394916872363, "Acute myocardial infarction": 2.8617991978765023, "Acute respiratory failure": 2.695192903565324, "Anal incontinence": 2.206531905684396, "Blood pressure diastolic abnormal": 13.753948699635435, "COVID-19 pneumonia": 2.2884836677368563, "Chronic respiratory failure": 19.23280302137393, "Constipation": 3.2903745057308997, "Coronavirus infection": 3.8549080581601096, "Cough": 2.682672985290688, "Death": 7.147434911904626, "Decreased appetite": 6.200325126992586, "Diarrhoea": 13.02846694064923, "Diarrhoea haemorrhagic": 2.884805684208494, "Diverticulitis": 3.2795509670615868, "Dyspepsia": 3.006162773041564, "Dyspnoea exertional": 8.314153551343185, "Epistaxis": 2.2470087561358683, "Faeces discoloured": 2.76097139749974, "Faeces soft": 27.11674947633393, "Flatulence": 5.593090078271459, "Forced vital capacity decreased": 89.14292732257697, "Gamma-glutamyltransferase increased": 4.293371678104928, "Gastric haemorrhage": 2.6180614604235624, "Gastrointestinal disorder": 5.779286093341786, "Gastrointestinal pain": 2.742896542182305, "Gastrointestinal perforation": 4.392510452123849, "Gastrointestinal sounds abnormal": 4.484790637477156, "General physical health deterioration": 2.2713233192511337, "Haemoptysis": 3.524722204336436, "Hepatic cytolysis": 2.5698406498407995, "Hepatic enzyme increased": 5.231652055886028, "Hepatotoxicity": 3.9754868498428086, "Hip fracture": 3.044727896251443, "Hypertransaminasaemia": 7.158299680220993, "Hypophagia": 4.469428165076442, "Hypoxia": 2.2809805020470924, "Idiopathic pulmonary fibrosis": 650.3447195237708, "Interstitial lung disease": 2.848202196193612, "Intestinal perforation": 4.069453398153047, "Investigation abnormal": 18.684351061546703, "KL-6 increased": 15.814963824351024, "Liver disorder": 2.3109187802046227, "Liver function test abnormal": 2.7050995841816503, "Liver function test increased": 9.71141303055552, "Lower gastrointestinal haemorrhage": 2.404607702312918, "Lung diffusion test decreased": 39.5815663846807, "Lung disorder": 4.593783756963166, "Lung neoplasm malignant": 5.500278878535834, "Lung transplant": 51.13058623378122, "Myocardial infarction": 2.170622258264545, "Nausea": 2.1212937130290035, "Nephrotic syndrome": 2.398954613152664, "Oxygen consumption increased": 26.952328427651786, "Oxygen saturation decreased": 7.071124092175325, "Physical deconditioning": 9.419122685306077, "Pneumomediastinum": 12.962014744564977, "Pneumonia": 2.949082973703358, "Pneumothorax": 12.751779894493763, "Post procedural complication": 2.691475955140743, "Productive cough": 7.921496209644519, "Pulmonary arterial hypertension": 3.181696056288685, "Pulmonary fibrosis": 10.79908655657334, "Pulmonary function test decreased": 16.866008493366138, "Pulmonary hypertension": 8.38786401808802, "Pulseless electrical activity": 14.659397352398202, "Respiratory disorder": 2.173575047090299, "Respiratory failure": 4.068429121951681, "Respiratory rate increased": 3.1611292400371265, "Right ventricular failure": 4.051303740074024, "Scleroderma": 8.986190619908276, "Seasonal allergy": 3.507581480832375, "Sputum discoloured": 2.947600543336244, "Taste disorder": 2.0028583095256924, "Tooth infection": 3.696739249755713, "Transaminases increased": 8.834113485337948, "Transient ischaemic attack": 2.369054124380918, "Varicose vein": 3.4721469064555444, "Vomiting": 2.462639384568805, "Weight decreased": 12.07469519066245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/805.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/805.json
index 7f6c6b510c7..cf68afa9358 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/805.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/805.json
@@ -1 +1 @@
-{"Acute left ventricular failure ": 891.8311966297554, "Acute myocardial infarction ": 8.323788079628846, "Acute respiratory failure ": 7.949871630144918, "Arrhythmia ": 2.1637002606442524, "Blood glucose decreased ": 3.954800841711125, "Blood glucose fluctuation ": 5.801736209922603, "Blood glucose increased ": 5.166667893991179, "Bronchitis ": 4.138791805920363, "Cardiac disorder ": 3.4550616560584406, "Cardiac failure ": 46.56060290582624, "Cardiac failure acute ": 18.328812141772666, "Cardiac failure congestive ": 65.80874903938171, "Cardiomyopathy ": 16.35629485735435, "Cardiovascular disorder ": 56.45751122080873, "Cholelithiasis ": 3.501837010707145, "Chronic left ventricular failure ": 1410.3886988342722, "Chronic obstructive pulmonary disease ": 2.5208491743472883, "Coronary artery disease ": 21.52815461128047, "Diabetes mellitus ": 4.606209068461874, "Dyspepsia ": 3.72242112220773, "Glycosylated haemoglobin increased ": 8.674524125061561, "Hyperglycaemia ": 2.9168262852476614, "Hyperlipidaemia ": 5.668924786666238, "Hypertensive heart disease ": 89.10909366480809, "Hypoglycaemia ": 2.1382806211245957, "Hypoglycaemic coma ": 4.400593851614851, "Intentional product misuse ": 4.727251592888439, "Left ventricular failure ": 70.64423012632452, "Myocardial infarction ": 6.590586636395497, "Pancreatic carcinoma ": 10.470210013694052, "Pancreatitis ": 14.258198894708364, "Pancreatitis acute ": 18.78576684086436, "Pemphigoid ": 30.333624450156545, "Product dose omission issue ": 3.463996280201897, "Renal disorder ": 2.805551393513519, "Respiratory failure ": 2.198608846248066, "Type 2 diabetes mellitus ": 6.253683177396747}
\ No newline at end of file
+{"Abnormal behaviour": 5.2414653370770194, "Abnormal weight gain": 11.24600716347155, "Abulia": 5.885712720504399, "Accidental death": 80.61057266553954, "Accidental exposure to product by child": 5.822704875884167, "Accidental overdose": 3.2736371967975995, "Acute psychosis": 5.764954605499914, "Acute pulmonary oedema": 2.4002479727512256, "Affect lability": 3.423857609458621, "Affective disorder": 4.633152852510166, "Aggression": 6.049375478457449, "Agitated depression": 36.114382596059535, "Agitation": 5.860095143716947, "Agitation neonatal": 9.70691018839118, "Agranulocytosis": 2.334362137864789, "Akathisia": 21.536792327260116, "Akinesia": 6.136414989644538, "Alanine aminotransferase increased": 2.184724733823512, "Alcohol withdrawal syndrome": 15.002089100367453, "Altered state of consciousness": 3.410629123317774, "Amimia": 48.02189748962015, "Ammonia increased": 2.901037255083975, "Anosognosia": 11.126218331054591, "Anticholinergic syndrome": 65.76329751970309, 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3.3947572251146, "Electrocardiogram abnormal": 3.8192751474286486, "Electroencephalogram abnormal": 4.942991346860855, "Embolism venous": 15.406257381372429, "Encephalitis autoimmune": 2.395997077733444, "Endotracheal intubation": 3.3650260536755736, "Enuresis": 2.614860116807801, "Eosinophil count decreased": 5.100606400011758, "Euphoric mood": 6.380174879928394, "Excessive eye blinking": 8.234773078068882, "Extrapyramidal disorder": 31.58777590685633, "Eye movement disorder": 2.0719253561255173, "Faecaloma": 6.011740708914863, "Feeling guilty": 13.110535302706676, "Flat affect": 4.068189504224402, "Flight of ideas": 30.208888592847487, "Fluid intake reduced": 2.7308819692231885, "Foaming at mouth": 2.2602944877163456, "Foetal exposure timing unspecified": 4.03452645745584, "Food craving": 4.019685283230825, "Frustration tolerance decreased": 4.375347611624641, "Galactorrhoea": 8.439398168021741, "Gastrointestinal hypomotility": 10.898148469486651, "Gastrointestinal necrosis": 2.935893180135387, "Gastrointestinal sounds abnormal": 5.160373831128488, "Gaze palsy": 3.189187351206502, "Generalised anxiety disorder": 5.024108968046135, "Generalised tonic-clonic seizure": 2.871823986264944, "Gestational diabetes": 9.59414354391342, "Glucose urine present": 4.3723505993512, "Grandiosity": 19.549015445914836, "Granulocytopenia": 4.153480221278849, "Gynaecomastia": 2.882390816938738, "Haematocrit increased": 2.2044986944269884, "Haemodynamic instability": 2.622588426835528, "Hallucination": 2.0075955770424336, "Hallucination, auditory": 12.94387113976042, "Hallucination, visual": 3.3034075623418504, "Hanging": 26.64046607765923, "Heat stroke": 11.723972374523012, "Hepatic enzyme abnormal": 2.0677164576301026, "Hepatic function abnormal": 3.7477431263674426, "Hepatic steatosis": 2.371628646515697, "High density lipoprotein decreased": 3.141563700545401, "Hirsutism": 8.27568154536018, "Homicide": 5.192168250645442, "Hostility": 7.5823493384751135, "Humerus fracture": 3.3323283876414624, "Hunger": 2.158804045123876, "Hyperammonaemia": 3.911850123361381, "Hyperammonaemic encephalopathy": 6.6482093421491495, "Hyperglycaemic hyperosmolar nonketotic syndrome": 12.929237270526803, "Hyperlipidaemia": 2.7456607852480346, "Hypernatraemia": 6.285791413945478, "Hyperphagia": 7.080802825994087, "Hyperprolactinaemia": 39.33898268311663, "Hyperreflexia": 8.815026618036176, "Hypersomnia": 2.293520671953554, "Hyperthermia": 9.634391605150622, "Hypertonia": 7.773155400848025, "Hypertriglyceridaemia": 5.820213556262758, "Hyperuricaemia": 3.7928071018760345, "Hypoalbuminaemia": 2.2381667009298627, "Hypocalcaemia": 2.199243004406199, "Hypomania": 7.622341997319465, "Hyponatraemia": 2.578960885621647, "Hypophagia": 3.0590796376534364, "Hyporeflexia": 2.223352797263866, "Hypothermia": 7.957037005582945, "Hypotonia neonatal": 5.823162045329704, "Hypoventilation": 4.8352000600916565, "Hypoxic-ischaemic encephalopathy": 3.4253564516524757, "Ileus paralytic": 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4.958709870760828, "Leukopenia": 3.0285781582858804, "Libido increased": 5.217505782978675, "Lipids increased": 4.002647389762856, "Liver function test abnormal": 2.078526082583274, "Logorrhoea": 3.668750630263319, "Long QT syndrome": 8.324191758799584, "Lymphocyte count decreased": 4.587552017378011, "Major depression": 5.486867594476901, "Mania": 10.67060763158964, "Megacolon": 9.862532789941936, "Meige's syndrome": 45.42950352213745, "Mental disorder": 2.3009684849298, "Mental impairment": 4.100635304634359, "Mental status changes": 5.562990810457161, "Metabolic disorder": 6.068591727051416, "Metabolic syndrome": 34.30861950775119, "Miosis": 9.238745818241592, "Moaning": 4.474357966515993, "Mood altered": 2.07419135758458, "Mucosal dryness": 3.956938407911127, "Muscle contractions involuntary": 2.186047644428774, "Muscle rigidity": 19.996983856505988, "Mutism": 20.67792722801024, "Mydriasis": 2.958038019111347, "Myocardial hypoxia": 254.2160090242065, "Myocardial reperfusion injury": 397.1334500894946, "Myoclonic epilepsy": 3.885844457550731, "Myoclonus": 3.424065871775253, "Myoglobin blood increased": 2.229508862604197, "Myoglobinuria": 8.890888949167591, "Negativism": 30.97489053999608, "Neonatal respiratory distress": 2.866774004028092, "Nephrogenic diabetes insipidus": 4.34587371598508, "Neuroleptic malignant syndrome": 56.44045296254424, "Neutropenia": 2.404310139043383, "Neutrophil count increased": 6.995182039302367, "Neutrophilia": 3.442193474294328, "Normal newborn": 2.877750509856146, "Obesity": 5.668358845058338, "Obsessive thoughts": 6.923958139909304, "Obsessive-compulsive disorder": 11.01566196086666, "Obsessive-compulsive symptom": 47.47554614929604, "Oculogyric crisis": 25.75054062010908, "Opisthotonus": 4.452219264325884, "Oromandibular dystonia": 13.727973206769429, "Orthostatic hypotension": 2.932537320826188, "Ovarian cancer": 2.659419105763911, "Overdose": 4.3147112812479325, "Overweight": 5.306368974698866, "Painful erection": 25.291241206496277, "Pancreatic neuroendocrine tumour metastatic": 11.679722798184752, "Pancreatitis haemorrhagic": 10.230292281644529, "Pancreatitis necrotising": 5.879422448152801, "Paranoia": 5.36308847427398, "Parkinsonian gait": 10.394203628700444, "Parkinsonian rest tremor": 19.91247053119856, "Parkinsonism": 25.268399196977267, "Paternal exposure timing unspecified": 10.929856526764167, "Persecutory delusion": 19.831389101210128, "Personality disorder": 3.24452637666751, "Phagophobia": 205.86189425043077, "Phobia": 7.32398977372985, "Pituitary tumour benign": 5.49750503197662, "Pleurothotonus": 69.57821830741264, "Pneumonia aspiration": 6.4853034608490665, "Pneumonitis aspiration": 9.079364323786155, "Poisoning": 7.453850389050909, "Poisoning deliberate": 9.653128150946989, "Polydipsia": 7.21641052696354, "Polydipsia psychogenic": 26.0718592700784, "Polyuria": 2.237373156186833, "Post-injection delirium sedation syndrome": 20.930327179253307, "Post-traumatic stress disorder": 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psychosis": 106.8802633669788, "Red blood cell count increased": 3.3469815599066566, "Reduced facial expression": 11.513979003407526, "Respiratory acidosis": 3.5409656295284937, "Respiratory arrest": 3.744083445579604, "Respiratory depression": 4.4541621120866735, "Respiratory distress": 2.3127941909966103, "Resting tremor": 34.26942861664295, "Restless legs syndrome": 2.7536926975378235, "Restlessness": 3.226822623022316, "Rhabdomyolysis": 4.960286461854865, "Salivary hypersecretion": 11.728130986716232, "Schizoaffective disorder": 17.627249017661228, "Schizophrenia": 42.37773851107194, "Sedation": 15.904715237993514, "Sedation complication": 12.235239754652016, "Selective eating disorder": 7.2479894367861615, "Self-destructive behaviour": 7.411951188836761, "Self-injurious ideation": 8.086737669676035, "Self-medication": 3.218984942309599, "Seminoma": 58.65950028536193, "Serotonin syndrome": 8.544814339110005, "Sexual dysfunction": 2.7632843203783835, "Sexually inappropriate behaviour": 26.614216191219576, "Sinus bradycardia": 2.123419007987187, "Sinus rhythm": 5.454095417892417, "Sinus tachycardia": 5.1921512634924, "Slow response to stimuli": 2.8951029269823354, "Slow speech": 3.9105703484378607, "Sluggishness": 2.867497600608852, "Small for dates baby": 3.445632556819413, "Snoring": 2.157422864159865, "Social avoidant behaviour": 5.602445324083959, "Somatic delusion": 79.88390378582609, "Somatic symptom disorder": 2.747834790323098, "Somnambulism": 5.75692459268468, "Somnolence": 3.6048097307842712, "Sopor": 6.380581134936578, "Spasmodic dysphonia": 62.14673550028079, "Speech disorder": 2.8553809589268218, "Stenosis": 5.311958906274488, "Stupor": 3.6873634011450624, "Substance-induced psychotic disorder": 22.210183903627883, "Sudden cardiac death": 14.03453845673455, "Sudden death": 3.575593560797938, "Suicidal behaviour": 3.791926032264991, "Suicidal ideation": 2.6095802934648327, "Suicide attempt": 5.049150132748029, "Suspected suicide": 9.9570196718407, "Suspiciousness": 25.298885349404028, "Systolic dysfunction": 4.34097442795342, "Tachycardia": 2.515372120166837, "Tachyphrenia": 2.6399098767488387, "Tachypnoea": 3.701659954096424, "Talipes": 2.43979613169876, "Tardive dyskinesia": 35.108967433302034, "Tension": 2.923672521766745, "Therapy non-responder": 2.1809495833594674, "Thinking abnormal": 4.254518326017714, "Tobacco interaction": 112.25694605794094, "Tongue biting": 3.296366134969724, "Tonic convulsion": 2.7114853524279945, "Torsade de pointes": 5.666431919770682, "Torticollis": 11.147504125280523, "Toxicity to various agents": 8.096818824393637, "Transaminases increased": 2.776344412093615, "Treatment noncompliance": 6.938109740420761, "Tremor": 2.2649206727848794, "Troponin T increased": 3.72592490790784, "Troponin increased": 4.912705068373066, "Type 1 diabetes mellitus": 2.2963295938062327, "Type 2 diabetes mellitus": 3.0060096751705485, "Unresponsive to stimuli": 4.83493789989098, "Urinary hesitation": 2.511955637737961, "Urinary incontinence": 2.250519046087195, "Urinary retention": 2.806900265147735, "Vascular neoplasm": 111.09027411685008, "Ventricular arrhythmia": 4.674510244012757, "Violence-related symptom": 7.464385334260461, "Water intoxication": 12.225312067202616, "Weight increased": 7.90427825122978, "White blood cell count increased": 3.8542104806507615, "Withdrawal syndrome": 2.7164537474532624, "Wrong patient": 17.456980842245745, "Wrong patient received product": 11.01215987033834, "Xanthoma": 34.38870391961016}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/806.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/806.json
index 6623ae15ee2..51a9087f744 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/806.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/806.json
@@ -1 +1 @@
-{"Diarrhoea ": 9.419824304962695, "Nausea ": 2.100997219578719, "Neutropenia ": 13.199462059253287, "Off label use ": 2.692327849706278}
\ No newline at end of file
+{"Acute myeloid leukaemia": 18.23616333143703, "Alanine aminotransferase increased": 2.6783661276712576, "Anaemia": 23.247953308635143, "Asthenia": 2.6324041922673658, "Carbohydrate antigen 125 increased": 103.59709160310312, "Disease progression": 3.045463987405114, "Drug resistance": 8.3094419787056, "Dyspnoea exertional": 2.682179775329874, "Haematotoxicity": 31.74342982354335, "Haemoglobin abnormal": 28.29443893371044, "Haemoglobin decreased": 5.347890704924302, "Leukopenia": 7.875211174854406, "Lymphopenia": 14.286898213966388, "Malignant neoplasm progression": 20.891983203226204, "Metastases to bone": 14.800626475506084, "Metastases to central nervous system": 13.141729510807032, "Metastases to liver": 20.42826539110154, "Metastases to lung": 14.206373871789513, "Metastases to lymph nodes": 16.567588547047233, "Metastases to pelvis": 142.24335558653013, "Metastases to spine": 40.95569226411904, "Myelodysplastic syndrome": 84.74352439504008, "Myelosuppression": 10.05857879072759, "Nausea": 2.37695651737095, "Neutropenia": 6.65415576644455, "Off label use": 3.257202495370145, "Ovarian cancer recurrent": 228.44150019229264, "Pancytopenia": 5.092811938793196, "Platelet count decreased": 2.8028821722650235, "Pneumonitis": 6.5722731535846455, "Product use in unapproved indication": 3.2434256667481565, "Prostatic specific antigen increased": 9.570237534789136, "Red blood cell count decreased": 5.355463297249801, "Thrombocytopenia": 8.60195666117746, "White blood cell count decreased": 3.086105053582992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/807.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/807.json
index 81dd1f52ac2..479af6b4389 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/807.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/807.json
@@ -1 +1 @@
-{"Drug interaction ": 22.434415304983077}
\ No newline at end of file
+{"Alopecia areata": 508.9692650940183, "Drug-induced liver injury": 41.09899338888812, "Hepatic function abnormal": 20.77731600369258, "Pancytopenia": 10.366808009349796, "Urticaria": 3.0713192100334337}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/808.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/808.json
index bb78a215e4c..474f82d0fc2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/808.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/808.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.6569679122568943, "Anaemia ": 5.872784722671446, "Asthenia ": 2.8679388065276683, "Diarrhoea ": 8.289963517713689, "Erythema ": 3.246179739521284, "Neutropenia ": 5.323793637158617, "Paraesthesia ": 7.451828323924774, "Pruritus ": 2.7383901174834024}
\ No newline at end of file
+{"Herpes zoster": 6.555151153543076}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/809.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/809.json
index 1612e81fa72..ff20a9078b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/809.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/809.json
@@ -1 +1 @@
-{"Eye irritation ": 91.33153698774557, "Eye pain ": 21.302859423327806, "Eye pruritus ": 79.82687449024846, "Eye swelling ": 22.69356933040864, "Hypersensitivity ": 2.8629856762911507, "Lacrimation increased ": 52.36524843309823, "Ocular hyperaemia ": 43.74035806725436, "Pruritus ": 2.132204806547896, "Vision blurred ": 10.786548381990274, "Visual impairment ": 5.85637179482383}
\ No newline at end of file
+{"Acute hepatic failure": 8.180619852071928, "Alanine aminotransferase increased": 2.2722500177165923, "Anaemia": 4.7249467804610585, "Anuria": 3.2301788820576784, "Ascites": 11.281419352584866, "Aspartate aminotransferase increased": 2.670807948973907, "Blood albumin decreased": 9.268549993358006, "Blood alkaline phosphatase increased": 2.070767466038057, "Blood bilirubin abnormal": 54.23594779242484, "Blood bilirubin increased": 31.52470415886541, "Cheilitis": 17.171008689501928, "Dermatitis bullous": 4.730784363599918, "Drug ineffective": 6.509738700617503, "Eczema": 2.2986677950224768, "Encephalopathy": 3.251525412656104, "Haemoglobin decreased": 3.2054666526803826, "Hepatic cancer": 5.621424277234415, "Hepatic cirrhosis": 12.51313699003402, "Hepatic encephalopathy": 20.83149632821512, "Hepatic failure": 18.711822179841597, "Hepatic function abnormal": 2.22619695749173, "Hepatic lesion": 8.933914118091076, "Hepatitis C": 119.83930948018384, "Hepatitis C RNA": 530.1486413459464, "Hepatitis C RNA increased": 68.92528886197735, "Hepatitis C virus test positive": 43.4134411319507, "Hepatitis acute": 4.657834937980569, "Hepatocellular carcinoma": 20.56345777099131, "Hepatorenal syndrome": 50.17000056017976, "Hyperbilirubinaemia": 61.468550347275226, "Irritability": 2.391928031987029, "Jaundice": 14.887130439995582, "Lip oedema": 3.1115354828713917, "Liver transplant": 19.22634199254209, "Lung adenocarcinoma": 28.043911661689865, "Lymphopenia": 4.572777251010968, "Multiple organ dysfunction syndrome": 2.102722631470594, "Off label use": 9.880492031367467, "Photosensitivity reaction": 61.43671189451053, "Portal vein thrombosis": 16.432735008781343, "Product quality issue": 13.823559289434725, "Pruritus": 2.4286106342395577, "Sinus bradycardia": 7.737885858959147, "Skin exfoliation": 2.2929879370282253, "Solar dermatitis": 83.46544440553645, "Sudden death": 5.140131934387264, "Sunburn": 74.22520496059998, "Therapy non-responder": 2.742954068419378, "Toxic skin eruption": 4.347186937978319, "Transaminases increased": 4.391106423952661, "Transplant rejection": 10.127033979340144, "Treatment failure": 8.773391275663554, "Treatment noncompliance": 2.5238475424439133, "Viral load increased": 40.2837904915344, "Viral mutation identified": 12.719277201096364, "Virologic failure": 12.010557119057042, "White blood cell count increased": 2.0559923532803994}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/81.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/81.json
index c57ec5a8e4a..237b119cda4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/81.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/81.json
@@ -1 +1 @@
-{"Acute respiratory distress syndrome ": 2.085492965630205, "Antineutrophil cytoplasmic antibody positive ": 334.8885519514293, "Anxiety ": 4.185293611286958, "Arteriosclerosis ": 94.0594474118258, "Arteriosclerosis coronary artery ": 134.89782747636536, "Asthma ": 9.537442769045224, "Asthma-chronic obstructive pulmonary disease overlap syndrome ": 45.99147193150504, "Breast conserving surgery ": 25.051756487839278, "Bronchiectasis ": 8.993173748749316, "Bronchitis ": 2.214297550283463, "Bronchospasm paradoxical ": 28.00963158520351, "Candida infection ": 5.039620040699715, "Capillaritis ": 340.98668249017163, "Cardiac murmur ": 3.461336603362694, "Cardiac pacemaker insertion ": 4.871709030402021, "Choking ": 5.441184170511055, "Chronic obstructive pulmonary disease ": 16.10641401225638, "Condition aggravated ": 7.020843906629771, "Conjunctivitis allergic ": 501.9557273661868, "Contraindicated product prescribed ": 16.008023053548527, "Cough ": 2.5110902760222693, "Dust allergy ": 778.6771379219762, "Dysphonia ": 2.4295926644206123, "Dyspnoea ": 3.6687668112659177, "Dyspnoea exertional ": 2.2340183646842786, "Dysuria ": 2.443610979932404, "Emphysema ": 11.376633733691977, "Eosinophilic granulomatosis with polyangiitis ": 163.9112214138665, "Expired product administered ": 2.292877327935013, "Eye disorder ": 3.447924216052355, "Forced expiratory volume decreased ": 131.26424118667836, "Full blood count abnormal ": 35.23152165012163, "Glaucoma ": 3.4755825787962182, "Haemoptysis ": 38.18157543367143, "Hospitalisation ": 2.3193984297174604, "Hypomania ": 6.456693255728992, "Hypothyroidism ": 18.002388832965554, "Hypoxia ": 29.450185681376823, "Ill-defined disorder ": 3.0078279284266363, "Inability to afford medication ": 10.108351672173235, "Jaundice cholestatic ": 5.676240934346821, "Labelled drug-drug interaction medication error ": 3.283541057763978, "Loss of personal independence in daily activities ": 17.521459101361557, "Lower respiratory tract infection ": 2.043642694587992, "Lung disorder ": 28.642836382227028, "Lung neoplasm malignant ": 9.887614046288872, "Mite allergy ": 803.8175693667865, "Mycotic allergy ": 1029.534557542628, "Nasal congestion ": 2.2816295670798845, "Nasal polyps ": 7.378232226872656, "Neoplasm malignant ": 2.034132010099591, "Neuritis ": 304.8002359017744, "Neurological symptom ": 136.99192218843612, "Nodule ": 85.75191330559532, "Normochromic normocytic anaemia ": 386.41575199834926, "Obstruction ": 14.588579984397548, "Obstructive airways disorder ": 67.18526812791438, "Oral candidiasis ": 5.600641232710296, "Oral pain ": 2.122968996765015, "Oxygen therapy ": 10.732583349401162, "Pain in extremity ": 2.045389340495568, "Pneumonia ": 3.686074107067511, "Product complaint ": 8.610980730373356, "Product dispensing error ": 3.132968610967063, "Product dose omission issue ": 2.7986880037180177, "Product prescribing issue ": 6.290351626603902, "Product use in unapproved indication ": 2.415880711547481, "Productive cough ": 30.20140585661644, "Pulmonary alveolar haemorrhage ": 150.97359556812924, "Pulmonary congestion ": 2.914447132334597, "Pulmonary embolism ": 7.345504148702695, "Pulmonary fibrosis ": 46.04900511815978, "Pulmonary mass ": 2.2731693711920737, "Pulmonary resection ": 133.00329837308163, "Pulmonary vasculitis ": 1051.523204597621, "Respiratory disorder ": 3.074412450169052, "Respiratory symptom ": 199.963374810061, "Rhinitis allergic ": 4.194067754478722, "Rhinorrhoea ": 2.513978171807507, "Sarcoidosis ": 5.201127295567908, "Schizophrenia ": 3.902714330724172, "Sinus disorder ": 6.188026535275771, "Sinusitis ": 2.0928202214131453, "Sleep disorder due to a general medical condition ": 8.869511447141978, "Therapeutic product effect incomplete ": 3.7859899798743952, "Therapy cessation ": 3.964822024964884, "Total lung capacity increased ": 60.45627678256857, "Treatment noncompliance ": 2.2992206940686217, "Urinary retention ": 6.201584568406242, "Vasculitis ": 4.830825194396986, "Wheezing ": 5.525215327544076, "Wrong technique in device usage process ": 21.615788087378544}
\ No newline at end of file
+{"Acute kidney injury": 3.6412271830490575, "Anaemia": 2.371752324636192, "Bacteraemia": 27.023867156305663, "Bronchopulmonary aspergillosis": 62.51483531482919, "COVID-19 pneumonia": 38.77825477129275, "Candida infection": 44.95447980235934, "Cellulitis": 6.978286938413132, "Condition aggravated": 7.618217268206459, "Drug ineffective": 3.2711145261082453, "Drug resistance": 32.48423929122619, "Eye infection fungal": 1305.0195962222592, "Haemodynamic instability": 68.80844849758704, "Intraocular pressure test": 1512.9765152147052, "Intraocular pressure test abnormal": 697.7867588970669, "Klebsiella infection": 74.67587544324111, "Multi-organ disorder": 149.71178760117215, "Multiple organ dysfunction syndrome": 32.04139621301433, "Neutropenia": 8.282841627377136, "Pancytopenia": 3.9428006652885976, "Pathogen resistance": 41.06116395601374, "Peritonitis": 33.843766951424854, "Renal impairment": 3.5051184866331315, "Respiratory failure": 4.206302224861135, "Scedosporium infection": 1236.0227957260513, "Sepsis": 7.635830207299897, "Septic shock": 22.45631767990235, "Thrombocytopenia": 2.726107242298288}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/810.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/810.json
index 061fa678095..ead7cb2a29c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/810.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/810.json
@@ -1 +1 @@
-{"Addison's disease ": 10.721286382533403, "Adrenal disorder ": 24.177262636318197, "Adrenal insufficiency ": 89.26868147766206, "Adrenocortical insufficiency acute ": 27.73348853346601, "Adrenocorticotropic hormone deficiency ": 314.68175790908253, "Alanine aminotransferase increased ": 2.1454070062029933, "Amylase increased ": 4.95806308725641, "Aspartate aminotransferase increased ": 2.3023644968115566, "Autoimmune colitis ": 95.6025489184596, "Autoimmune dermatitis ": 78.15567788188058, "Autoimmune haemolytic anaemia ": 4.155068233475303, "Autoimmune hepatitis ": 26.58098832801254, "Autoimmune nephritis ": 37.69317824285383, "Autoimmune pancreatitis ": 41.17946796875452, "Autoimmune thyroiditis ": 10.513798600314455, "Blood corticotrophin decreased ": 62.27091645409207, "Blood creatine phosphokinase increased ": 2.1419227580911206, "Blood thyroid stimulating hormone abnormal ": 19.05353379167592, "Blood thyroid stimulating hormone decreased ": 10.746159253462151, "Blood thyroid stimulating hormone increased ": 2.940238192872663, "Brain oedema ": 2.2233192991500506, "Bronchopulmonary aspergillosis ": 2.852820722390136, "C-reactive protein increased ": 2.6225406050329614, "Central hypothyroidism ": 26.05312368843499, "Cholangitis ": 9.07120859395352, "Cholangitis sclerosing ": 18.55649613057516, "Cholecystitis ": 2.9151497116995624, "Cholestasis ": 2.398980272128844, "Chronic gastritis ": 3.407306997076868, "Colitis ": 37.01876210175181, "Colitis microscopic ": 5.047996020770578, "Coronavirus infection ": 3.072776966096285, "Cortisol decreased ": 17.502826210074264, "Cytokine release syndrome ": 11.937667423042948, "Cytomegalovirus enterocolitis ": 13.245436749455424, "Decreased appetite ": 2.909941317599181, "Dermatitis ": 4.015389865251529, "Dermatitis psoriasiform ": 6.18950933479755, "Diabetic ketoacidosis ": 3.257024816621925, "Diarrhoea ": 2.047321335303416, "Disseminated intravascular coagulation ": 6.33840348610658, "Drug eruption ": 5.390890298927222, "Drug-induced liver injury ": 4.198966253786695, "Duodenal ulcer ": 2.243668147278874, "Duodenitis ": 8.178438769507647, "Dyslalia ": 5.147577799946268, "Encephalitis ": 10.964496760472093, "Encephalitis autoimmune ": 13.15738855375916, "Endocrine disorder ": 19.05909630543023, "Enteritis ": 6.857863249905643, "Enterocolitis ": 30.508664701013632, "Eosinophil count increased ": 4.270700288981342, "Erythema multiforme ": 7.386131501351977, "Eyelid ptosis ": 5.760881421450782, "Febrile neutropenia ": 2.621422649534555, "Fulminant type 1 diabetes mellitus ": 176.56552251434485, "Gastritis ": 2.026011428351472, "Gastrointestinal perforation ": 4.875137917493226, "Glucocorticoid deficiency ": 27.08891849697116, "Graves' disease ": 3.2690845328398903, "Guillain-Barre syndrome ": 3.6578166407226256, "Haemophagocytic lymphohistiocytosis ": 16.57668238767877, "Hair colour changes ": 2.031473398392185, "Hepatic cytolysis ": 4.644697985158562, "Hepatic failure ": 2.0937343647489457, "Hepatic function abnormal ": 8.778091511202947, "Hepatitis ": 9.805443579049854, "Hepatitis acute ": 2.721252679289698, "Hepatitis fulminant ": 4.283665611637545, "Hepatotoxicity ": 3.769746093408006, "Hypercalcaemia ": 2.2228626430324225, "Hyperlipasaemia ": 10.321826929736323, "Hyperthyroidism ": 16.879856701432683, "Hypertransaminasaemia ": 2.152801648897868, "Hypophysitis ": 166.2949415065339, "Hypopituitarism ": 224.7886056633029, "Hypothalamo-pituitary disorder ": 61.05255206910652, "Hypothyroidism ": 19.828938271863997, "Immune thrombocytopenia ": 3.2852145534871084, "Immune-mediated adrenal insufficiency ": 233.0824053732555, "Immune-mediated adverse reaction ": 111.99013875702488, "Immune-mediated arthritis ": 91.7969739074402, "Immune-mediated cholangitis ": 70.12170709435715, "Immune-mediated dermatitis ": 385.580392753696, "Immune-mediated encephalitis ": 68.50200807486466, "Immune-mediated endocrinopathy ": 135.6052457121074, "Immune-mediated enterocolitis ": 153.57751843105626, "Immune-mediated gastritis ": 80.50611893721674, "Immune-mediated hepatic disorder ": 206.16830038711043, "Immune-mediated hepatitis ": 99.53363435730144, "Immune-mediated hyperthyroidism ": 59.723152833924566, "Immune-mediated hypophysitis ": 136.43005773823856, "Immune-mediated hypothyroidism ": 55.93186619878118, "Immune-mediated lung disease ": 152.35088760516322, "Immune-mediated myasthenia gravis ": 37.014866421035, "Immune-mediated myocarditis ": 71.98375210372812, "Immune-mediated myositis ": 53.16995419712262, "Immune-mediated nephritis ": 108.7827885815122, "Immune-mediated neuropathy ": 37.32379813315822, "Immune-mediated pancreatitis ": 105.10613000328917, "Immune-mediated renal disorder ": 98.88086835554972, "Immune-mediated thyroiditis ": 85.8837163156792, "Immune-mediated uveitis ": 54.84933703834195, "Infectious pleural effusion ": 7.630901397794385, "Infusion related reaction ": 2.671359213541632, "Intentional product use issue ": 16.126217029358234, "Interstitial lung disease ": 15.237270037331374, "Intestinal perforation ": 3.459910889222848, "Large intestine perforation ": 3.873264263300012, "Leukoderma ": 230.95446120214768, "Lichenoid keratosis ": 6.208279406740189, "Lipase increased ": 3.2232245572285403, "Liver disorder ": 11.26697223504703, "Lung opacity ": 4.340232951173019, "Lymphangiosis carcinomatosa ": 11.343486180993914, "Lymphocytic hypophysitis ": 110.31049889217404, "Malignant neoplasm progression ": 25.993291592963157, "Malignant pleural effusion ": 7.970671401605895, "Meningitis ": 4.957867972420475, "Meningitis aseptic ": 9.269458446645515, "Metastases to bone ": 3.940960003961727, "Metastases to central nervous system ": 13.022718873683932, "Metastases to liver ": 3.0259874143756504, "Metastases to lung ": 3.818139964867101, "Metastases to lymph nodes ": 4.581561098716215, "Metastases to meninges ": 5.882507387465225, "Metastases to spine ": 6.397980894324145, "Metastatic malignant melanoma ": 3.885011201384616, "Myasthenia gravis ": 22.258222480237016, "Myasthenic syndrome ": 9.244769872030815, "Myocarditis ": 6.062662293770092, "Myositis ": 25.150991347116992, "Nephritis ": 13.70680988880464, "Neuropathy peripheral ": 2.7190084123034666, "Neutrophil count decreased ": 3.676145429187547, "Non-small cell lung cancer ": 430.24269236953, "Oesophagitis ": 2.219618530629032, "Organising pneumonia ": 12.062849410281848, "Pancreatic enzymes increased ": 7.751427497641741, "Pemphigoid ": 4.0324965854222174, "Performance status decreased ": 3.0128219635834146, "Peripheral sensory neuropathy ": 4.0890285886855136, "Peritonitis ": 2.603082735384791, "Physical deconditioning ": 3.407527251903232, "Pituitary enlargement ": 66.88881843522914, "Platelet count decreased ": 2.11562675035154, "Pleural effusion ": 2.898203566072025, "Pneumocystis jirovecii pneumonia ": 3.897909439326853, "Pneumonia aspiration ": 3.1114679618671586, "Pneumonia bacterial ": 7.333087599237727, "Pneumonitis ": 22.54156935062784, "Polyarthritis ": 3.054261960266129, "Polymyalgia rheumatica ": 7.063942355122454, "Polymyositis ": 9.135383838466224, "Prescribed overdose ": 4.195065923211207, "Prescribed underdose ": 4.590715224437839, "Primary adrenal insufficiency ": 35.38583373398441, "Primary hypothyroidism ": 32.870005717940174, "Pulmonary toxicity ": 15.986156831300322, "Radiation pneumonitis ": 32.73041213859531, "Rash ": 2.518404743878045, "Rash maculo-papular ": 2.797687070726397, "Renal disorder ": 2.858053983501152, "Renal impairment ": 2.1334675891689945, "Sarcoidosis ": 3.400919556746724, "Secondary adrenocortical insufficiency ": 214.4315939123931, "Sialoadenitis ": 10.437767186324118, "Silent thyroiditis ": 185.3268309983824, "Sjogren's syndrome ": 3.701618463095721, "Skin disorder ": 7.958009716743746, "Skin toxicity ": 5.206369224972339, "Steroid diabetes ": 7.85353687757981, "Stevens-Johnson syndrome ": 2.238393996782843, "Thrombophlebitis migrans ": 42.0414189899959, "Thyroid disorder ": 13.751972503811968, "Thyroiditis ": 65.88600664414933, "Thyroiditis subacute ": 7.0407337600354944, "Thyrotoxic crisis ": 12.941417456050493, "Toxic epidermal necrolysis ": 2.503009088371614, "Troponin increased ": 2.364477633319907, "Tubulointerstitial nephritis ": 9.04539935680851, "Tumour haemorrhage ": 7.962916417110066, "Tumour lysis syndrome ": 4.7530033151256585, "Tumour pseudoprogression ": 62.74309221286461, "Type 1 diabetes mellitus ": 21.305147466049306, "Uveitis ": 7.802749831210593, "Vitiligo ": 11.99276302293395, "Vogt-Koyanagi-Harada disease ": 39.36864820526257}
\ No newline at end of file
+{"Accident": 3.0560000578424718, "Allergy to animal": 59.32984910299365, "Allergy to chemicals": 28.603803712803877, "Allergy to metals": 10.358844368220575, "Allergy to plants": 169.26475945914396, "Alpha 1 globulin increased": 120.36878387311698, "Alpha 2 globulin increased": 120.36878387311698, "Alveolar osteitis": 318.7586976707087, "Anaphylactic reaction": 2.512396029184417, "Aneurysm": 4.40249358657242, "Angioedema": 2.3895907341227023, "Animal scratch": 185.67252581782108, "Aortic aneurysm": 5.653587833466371, "Aphonia": 3.3721099954938776, "Arthropod bite": 4.197146191587922, "Asthma": 20.346827988105527, "Asthmatic crisis": 3.383708469849333, "Basophil percentage decreased": 196.92701971740385, "Biliary colic": 4.819021389575098, "Bladder pain": 18.33285830043456, "Blood immunoglobulin E increased": 30.1501693096447, "Blood iron decreased": 18.138459013915227, "Blood pressure diastolic decreased": 7.144085047970083, "Blood pressure diastolic increased": 6.992429422131104, "Blood pressure increased": 4.020683013744834, "Blood pressure systolic increased": 31.536616140820204, "Blood test abnormal": 3.871885739500208, "Blood urine present": 4.1951227717002055, "Body temperature decreased": 24.372736471663178, "Breath sounds abnormal": 7.964347537033042, "Bronchial obstruction": 7.327740282905513, "Bronchial secretion retention": 8.744701272398784, "Bronchiectasis": 12.984101242612734, "Bronchitis": 9.034516402009013, "Bronchopulmonary aspergillosis allergic": 59.38924747516311, "Burning sensation": 2.659606123404889, "Caffeine allergy": 348.7009279041925, "Calculus urinary": 19.93196970302666, "Carpal tunnel syndrome": 2.730198339044233, "Cellulitis": 2.8707600745308866, "Central pain syndrome": 38.994538446611536, "Chest discomfort": 3.2776089619074167, "Choking": 3.2891615325911583, "Choking sensation": 2.902193234491397, "Chronic obstructive pulmonary disease": 3.066504321630501, "Chronic sinusitis": 2.4469243442264736, "Chronic spontaneous urticaria": 25.720686189487587, "Cold agglutinins positive": 120.36878387311698, "Complex regional pain syndrome": 4.3960860695285895, "Concomitant disease aggravated": 4.17499954418396, "Cough": 6.020339620288138, "Crepitations": 3.466951939812779, "Cryopyrin associated periodic syndrome": 166.3342951205246, "Dermatitis contact": 12.252395812444208, "Dermoid cyst": 42.58544353536453, "Drug hypersensitivity": 12.100236756311274, "Dry throat": 2.7473402459910905, "Dust allergy": 33.67648981589529, "Dyslipidaemia": 2.05461209797516, "Dysphonia": 2.5906456856796725, "Dyspnoea": 3.0595210163080697, "Dyspnoea at rest": 7.883606400836514, "Dyspnoea exertional": 5.341413333284129, "Ear congestion": 13.275698166024204, "Ear discomfort": 2.828206002965592, "Ear infection": 5.442796546679945, "Ear swelling": 5.614240609592539, "Eosinophil count increased": 10.152072018524995, "Eosinophilic granulomatosis with polyangiitis": 8.364438316906998, "Exposure to allergen": 134.8784973278876, "Eye contusion": 5.905180235766008, "Eye discharge": 7.522479962561048, "Eye pruritus": 2.4847970967554747, "Eye swelling": 2.5476546693960875, "FEV1/FVC ratio decreased": 270.00714613289904, "Fear of injection": 6.0583624283716295, "Food allergy": 11.279349532479168, "Forced expiratory volume decreased": 158.1560419604483, "Forced vital capacity abnormal": 287.46289209490635, "Forced vital capacity decreased": 45.85813625126464, "Foreign body sensation in eyes": 5.035269928678844, "Frustration tolerance decreased": 10.278697576028922, "Full blood count abnormal": 7.520788507715626, "Gastroenteritis viral": 3.705803929475261, "General physical condition abnormal": 5.3275421019367855, "Giant cell arteritis": 3.940223867404386, "Heart rate decreased": 2.4739447079321923, "Heart rate increased": 3.555822147354092, "Hormone level abnormal": 3.615764357212993, "Humidity intolerance": 91.66923873710982, "Hypophagia": 2.0113416084135287, "Hyposmia": 5.218218186227153, "Hypoventilation": 26.95175352533294, "Illness": 3.233496463606925, "Immune system disorder": 2.5670965135502763, "Inappropriate schedule of product administration": 3.415038760984712, "Incorrect dose administered": 2.112145950998645, "Increased bronchial secretion": 8.759877987701966, "Increased upper airway secretion": 4.436976884740267, "Influenza": 2.8173939773281207, "Injection site bruising": 6.122515747877794, "Injection site haemorrhage": 2.417307957838827, "Joint dislocation": 4.119463676719956, "Lacrimation increased": 2.085990108360453, "Laryngitis": 4.807693472849243, "Ligament rupture": 9.48128426103908, "Ligament sprain": 7.911074769076015, "Loss of personal independence in daily activities": 2.742067620737908, "Lower respiratory tract infection": 6.1648206765535205, "Lung consolidation": 8.000287664795426, "Lung diffusion test decreased": 61.34769743867614, "Lung disorder": 4.268096113397694, "Lymphocyte percentage decreased": 10.778290163816123, "Mast cell activation syndrome": 7.426339932602821, "Mastocytosis": 24.91916317246141, "Mechanical urticaria": 4.674432427142381, "Middle insomnia": 25.710354400427477, "Mobility decreased": 2.052495902633112, "Monocyte percentage increased": 35.513330891210984, "Multiple allergies": 6.43060049207873, "Myopathy": 3.225093456426903, "Nasal congestion": 7.722894327642402, "Nasal discharge discolouration": 56.70101686564127, "Nasal oedema": 63.80063978344297, "Nasal polyps": 15.992216502929272, "Nasopharyngitis": 5.156305058763011, "Nerve compression": 6.083719585313036, "Normal newborn": 2.9099255665964208, "Obstructive airways disorder": 23.180545855912, "Oedema": 9.52409486284522, "Oropharyngeal pain": 2.697339071052693, "Oxygen saturation decreased": 2.272248401650129, "Papule": 2.25199199503836, "Peak expiratory flow rate decreased": 10.768058235521456, "Perfume sensitivity": 182.67388831611316, "Pharyngeal paraesthesia": 3.105491409213105, "Pneumonia": 4.848236409303391, "Post procedural complication": 3.2785576624075623, "Product availability issue": 2.810540385060881, "Productive cough": 14.519553369405612, "Pulmonary congestion": 2.3896043423336053, "Pulmonary function test decreased": 7.835922399951188, "Pulmonary thrombosis": 6.217827858317635, "Pyelonephritis": 2.136356078653054, "Quality of life decreased": 2.652828409914864, "Renal neoplasm": 13.809862839549446, "Respiration abnormal": 2.9660082018884024, "Respiratory disorder": 3.536288290223366, "Respiratory rate decreased": 4.997436598096935, "Respiratory rate increased": 7.518202008120821, "Respiratory tract congestion": 20.16810379728515, "Respiratory tract infection": 21.579277049734447, "Respiratory tract infection fungal": 27.66823789647862, "Restrictive pulmonary disease": 12.298080668952414, "Rhinorrhoea": 3.647360537415581, "Rubber sensitivity": 67.94068728294309, "Scratch": 11.26282197825315, "Seasonal allergy": 9.119354964688991, "Secretion discharge": 8.034071285506926, "Sensitivity to weather change": 69.57283026640259, "Sinus congestion": 6.591192978599831, "Sinus disorder": 5.590695888538009, "Sinus pain": 2.16842290078947, "Sinusitis": 6.780240809652442, "Skin atrophy": 4.502160002420401, "Skin fragility": 20.832489441107818, "Skin haemorrhage": 2.0342610067564024, "Skin plaque": 13.452309460882274, "Sleep disorder due to a general medical condition": 6.094390186721993, "Smoke sensitivity": 158.69988935407588, "Sneezing": 2.275884020133656, "Spinal disorder": 2.778171741274292, "Spinal fusion surgery": 8.48676698157165, "Spirometry abnormal": 64.87490353304156, "Sputum discoloured": 52.82794433218907, "Staphylococcus test positive": 21.076724178026428, "Stress": 4.224527376749693, "Superior mesenteric artery syndrome": 76.9554836299629, "Temperature intolerance": 2.974524826180535, "Therapeutic product effect incomplete": 2.427804415140953, "Therapeutic response decreased": 3.8016455624324794, "Therapeutic response shortened": 2.661885064679637, "Therapy partial responder": 2.8784627716174143, "Throat clearing": 29.01487082333644, "Throat tightness": 2.1367760539224325, "Total lung capacity increased": 29.51938339625691, "Type 2 diabetes mellitus": 2.241364770904635, "Upper respiratory tract infection": 3.777081023991815, "Upper-airway cough syndrome": 4.975529328744813, "Urticaria": 3.7346637040834727, "Urticarial vasculitis": 8.94657287559428, "Uterine cancer": 4.719583326786492, "Weight decreased": 2.0770818005148546, "Weight increased": 2.19368629719361, "Wheezing": 20.958887300906397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/811.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/811.json
index 53f056e6414..f8be6bbc91d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/811.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/811.json
@@ -1 +1 @@
-{"Drug abuse ": 90.323352896149}
\ No newline at end of file
+{"Device breakage": 96.78804880737115, "Device issue": 94.3523044656571, "Device malfunction": 17.31809282196066, "Device occlusion": 52.455892848644005, "Growth retardation": 106.84320022944836, "Incorrect dose administered": 17.005229286481775, "Incorrect dose administered by device": 80.89170409175007, "Injection site bruising": 14.132800957583653, "Injection site haemorrhage": 21.70108096101536, "Injection site pain": 4.978415039760371, "Intracranial pressure increased": 36.37607540367611, "Papilloedema": 46.948165393100005, "Product dose omission issue": 6.3097328956006296, "Product quality issue": 10.19779197379122, "Product storage error": 18.184002506667014, "Scoliosis": 42.924190453972365, "Wrong technique in product usage process": 9.245741986126196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/812.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/812.json
index 87cc0a4edee..7f0ea30f7a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/812.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/812.json
@@ -1 +1 @@
-{"Drug withdrawal syndrome neonatal ": 140.61201824392026, "Exposure via breast milk ": 155.96923786553293, "Foetal exposure during pregnancy ": 29.85030895051288, "Premature baby ": 39.337907723587456}
\ No newline at end of file
+{"Asthma": 9.563891615487076, "Chronic obstructive pulmonary disease": 27.054889076649783, "Death": 4.786606785309365, "Dyspnoea": 2.59516029036084, "Pneumonia": 3.3310341862791755, "Product use in unapproved indication": 4.530110648323824, "Tachycardia": 4.157971085769073}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/813.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/813.json
index 8c340a7c2a9..c07e4f4c09a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/813.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/813.json
@@ -1 +1 @@
-{"Cardio-respiratory arrest ": 150.16074822092176, "Completed suicide ": 119.96856128627208, "Death ": 16.92783660823521, "Drug abuse ": 43.20457782376957, "Respiratory arrest ": 54.78702525440836, "Toxicity to various agents ": 19.32159908955936}
\ No newline at end of file
+{"Abdominal pain": 6.083496424532279, "Acute hepatic failure": 4.943831422580731, "Amylase increased": 12.987830257816848, "Anaphylactic reaction": 21.3601212865308, "Anaphylactic shock": 8.05132336096863, "Angioedema": 7.957896384667647, "Antithrombin III decreased": 199.4393686798386, "Ascites": 4.633524375200259, "Blood bilirubin increased": 5.677846040567617, "Bronchial obstruction": 33.35428060941311, "Bronchospasm": 20.408095103681894, "Cerebral infarction": 3.2536025978735297, "Cerebral thrombosis": 21.4923986331292, "Cerebral venous sinus thrombosis": 24.661065207642363, "Cerebral venous thrombosis": 33.36910797971484, "Coagulopathy": 20.76582172902712, "Conjunctival hyperaemia": 13.5280991503291, "Cough": 2.9139625905428392, "Cyanosis": 3.650088132871653, "Dermatitis allergic": 2.3680730845568143, "Disseminated intravascular coagulation": 3.1381527471154307, "Drug hypersensitivity": 2.3823726608308453, "Enzyme activity decreased": 1281.4118526107254, "Erythema": 4.785590116849236, "Eyelid oedema": 9.766366263828298, "Face oedema": 6.828729344336477, "Febrile neutropenia": 11.620270303241446, "Flushing": 4.244007194839566, "Hepatic cytolysis": 2.109524913435433, "Hepatic failure": 2.808892939856285, "Hepatic steatosis": 8.173486909472942, "Hepatotoxicity": 14.902398467486284, "Hyperaemia": 46.04227133603601, "Hyperammonaemia": 16.736105301556027, "Hyperbilirubinaemia": 9.594333350376742, "Hypercholesterolaemia": 4.941555833393443, "Hyperglycaemia": 3.013646663986965, "Hyperlipidaemia": 7.555458285586069, "Hypersensitivity": 22.4520723404827, "Hypertriglyceridaemia": 68.31196412915445, "Hypoalbuminaemia": 22.7291142734394, "Hypofibrinogenaemia": 136.5486105268739, "Hypotension": 2.762871611203177, "Hypoxia": 3.025177610049864, "Infusion related reaction": 2.140329760239252, "Jugular vein thrombosis": 38.610380459476936, "Laryngeal oedema": 10.590741067372392, "Lip oedema": 17.640166133587712, "Lip swelling": 9.786255334873264, "Lipase increased": 15.420887004898502, "Liver disorder": 2.8780958641495054, "Mental status changes": 4.106175822646401, "Multiple organ dysfunction syndrome": 2.4180213598553766, "Oral discomfort": 3.657221832604946, "Oxygen saturation decreased": 5.553250401104061, "Pallor": 4.6777644530414975, "Pancreatic pseudocyst": 91.4197460099163, "Pancreatitis": 30.006224014559614, "Pancreatitis acute": 24.737938345639527, "Pancreatitis necrotising": 142.5177441968473, "Posterior reversible encephalopathy syndrome": 15.444983639313, "Pruritus": 2.186944729146414, "Pseudomonal sepsis": 32.13838074555922, "Rash maculo-papular": 2.2438521141607817, "Respiratory distress": 3.8703322688822, "Sepsis": 2.3274740570783186, "Septic shock": 3.514681479114153, "Shock": 6.7401354049871465, "Superior sagittal sinus thrombosis": 175.0772413754705, "Swelling face": 3.591286846989186, "Tachycardia": 2.219578356167184, "Underdose": 3.125211649446757, "Urticaria": 6.837261656068539, "Venoocclusive disease": 28.06381476138436, "Vomiting": 3.249539813639844}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/814.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/814.json
index 9c98d09db83..d08a59dce3f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/814.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/814.json
@@ -1 +1 @@
-{"Accidental overdose ": 16.81550769169097, "Cardio-respiratory arrest ": 12.917513539631653, "Completed suicide ": 13.00993482950356, "Death ": 2.390661946630833, "Drug abuse ": 32.69048150657904, "Drug dependence ": 30.465534988836197, "Drug screen positive ": 169.0674731848615, "Drug withdrawal syndrome ": 27.80155307735634, "Drug withdrawal syndrome neonatal ": 121.97395366582086, "Exposure via breast milk ": 51.87075023362419, "Foetal exposure during pregnancy ": 14.90641647128799, "Intentional overdose ": 7.009035091167111, "Jaundice neonatal ": 117.36398677284554, "Loss of consciousness ": 2.408752465899624, "Maternal exposure during pregnancy ": 3.468688777077636, "Overdose ": 14.344372271990986, "Product preparation issue ": 72.06738655976147, "Product use issue ": 3.147240815027134, "Somnolence ": 2.160562168160004, "Substance abuse ": 107.88791336990845, "Toxicity to various agents ": 11.557335086071468}
\ No newline at end of file
+{"Dyskinesia": 56.53748089743798, "Hallucination": 24.397770380650236}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/815.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/815.json
index bd611fbe1ac..9fd2be63e97 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/815.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/815.json
@@ -1 +1 @@
-{"Abdominal cavity drainage ": 58.94025901768779, "Abdominal distension ": 2.411093440593049, "Acute respiratory failure ": 6.627407599890486, "Adverse event ": 2.327514727965767, "Anaemia ": 2.272610108949878, "Angioplasty ": 6.684156862468332, "Aortic stenosis ": 2.2939467252497585, "Appendicectomy ": 3.6138740843140384, "Application site irritation ": 2.91534735939021, "Ascites ": 4.271538195890879, "Aspiration pleural cavity ": 24.128492591423804, "Atrial flutter ": 6.172755912901156, "Atrial septal defect repair ": 75.08161798233901, "Atrial tachycardia ": 2.2471425237514016, "Bacteraemia ": 3.0465467580142147, "Biopsy lung ": 27.363848627874397, "Blood culture negative ": 79.30190455036674, "Blood culture positive ": 17.568811855734396, "Blood iron decreased ": 6.606844225701386, "Blood magnesium decreased ": 3.040778531316962, "Blood potassium decreased ": 3.3082934855811588, "Brain natriuretic peptide increased ": 18.82167604106816, "Brain operation ": 4.88957517049012, "Bronchitis ": 2.846184472045227, "Cardiac ablation ": 11.329016963963122, "Cardiac failure ": 5.412022013307429, "Cardiac failure acute ": 3.359262120792448, "Cardiac failure congestive ": 4.206451872560103, "Cardiac failure high output ": 42.57542337612482, "Cardiac operation ": 9.174033394060451, "Cardiac output increased ": 52.08328124333962, "Cardiac pacemaker insertion ": 7.80984836768759, "Cardiopulmonary failure ": 2.2315585711772985, "Cardiovascular insufficiency ": 2.3552956199796875, "Cardioversion ": 6.732114424865575, "Catheter management ": 215.6054822398508, "Catheter placement ": 51.99438268895771, "Catheter removal ": 45.30606075588232, "Catheter site discharge ": 87.15336672724418, "Catheter site discolouration ": 158.12701944966307, "Catheter site erythema ": 88.63810958396907, "Catheter site haemorrhage ": 34.06766858394086, "Catheter site infection ": 66.03319479758315, "Catheter site irritation ": 136.5100199846976, "Catheter site pain ": 66.7711346235791, "Catheter site pruritus ": 152.28657713147533, "Catheter site rash ": 94.49781077549986, "Catheter site related reaction ": 29.90964209968053, "Catheter site swelling ": 61.04922292827579, "Catheterisation cardiac ": 28.22678027353397, "Catheterisation cardiac abnormal ": 32.37743745352398, "Cellulitis ": 2.3842422031615835, "Central venous catheterisation ": 20.51310157002341, "Chemotherapy ": 8.046396699684333, "Chest injury ": 4.975825637585127, "Cholecystectomy ": 3.4760526481695693, "Chronic obstructive pulmonary disease ": 3.2138893862480225, "Chronic respiratory failure ": 10.753568419610849, "Clostridium difficile infection ": 3.1238109779995007, "Complication associated with device ": 17.73794551162015, "Concomitant disease aggravated ": 16.37921211863474, "Concomitant disease progression ": 8.339735487176707, "Condition aggravated ": 3.733253601802327, "Congestive hepatopathy ": 11.679755674874226, "Cor pulmonale ": 8.722431909006533, "Death ": 7.382741041761854, "Dependence on oxygen therapy ": 17.24145250144739, "Dermatitis contact ": 5.437985883156154, "Device alarm issue ": 92.04116868389067, "Device breakage ": 13.271947843482458, "Device delivery system issue ": 4.329066948947553, "Device dislocation ": 38.55384531699643, "Device infusion issue ": 18.77176855363161, "Device issue ": 3.191988160904049, "Device leakage ": 21.341079510863743, "Device malfunction ": 2.925824197975192, "Device occlusion ": 9.98034018169426, "Device physical property issue ": 10.189654006060865, "Device related infection ": 15.88712741232774, "Device related sepsis ": 16.412946276396884, "Dialysis ": 15.951529258930387, "Diastolic dysfunction ": 2.066998286045499, "Disease complication ": 18.527501521369302, "Disease progression ": 4.781999671438772, "Dizziness postural ": 2.294030732177548, "Dyspnoea ": 3.594025366506276, "Dyspnoea at rest ": 9.182742724084338, "Dyspnoea exertional ": 9.887235955672486, "Emergency care ": 15.424324189258108, "Endarterectomy ": 55.20156363860814, "Endotracheal intubation ": 4.859550526111471, "Exercise tolerance decreased ": 2.0817930383592755, "Eye operation ": 2.9027119802160875, "Fall ": 2.109423885125416, "Fluid retention ": 27.254934958004824, "Flushing ": 3.906152391992839, "Gallbladder disorder ": 2.1534850725685084, "Gastroenteritis viral ": 3.641284591439321, "Gastrointestinal tube insertion ": 3.6347252609911336, "Generalised oedema ": 2.2570327864732005, "Haematocrit decreased ": 3.691477820664484, "Haemodialysis ": 4.524268557556765, "Haemoglobin decreased ": 3.5894246287493665, "Haemoptysis ": 3.142504543574226, "Head injury ": 2.1011970579048507, "Heart and lung transplant ": 116.41666058635778, "Heart transplant ": 15.5823138595535, "Hepatic cirrhosis ": 2.2101121475318863, "Hepatic enzyme abnormal ": 2.013816510584633, "Hernia repair ": 6.401501456095998, "Hip fracture ": 2.8809232767830277, "Hip surgery ": 3.2827659714076862, "Hospice care ": 16.391617581810436, "Hospitalisation ": 13.169944659777116, "Hypercapnia ": 4.335594664602928, "Hypervolaemia ": 55.13099627130838, "Hypotension ": 3.048599558976038, "Hypoxia ": 9.636424373122932, "Hysterectomy ": 3.969902988576408, "Idiopathic pulmonary fibrosis ": 2.911343106628782, "Illness ": 2.4235401947604167, "Increased bronchial secretion ": 2.9277141974958, "Infusion site erythema ": 8.782139207578485, "Infusion site haemorrhage ": 12.166212180259745, "Infusion site infection ": 40.25640677337759, "Infusion site irritation ": 29.90641575581305, "Infusion site pain ": 17.139914461970182, "Infusion site pruritus ": 9.688391800438271, "Infusion site swelling ": 13.12940867982921, "Infusion site warmth ": 21.855279499912218, "Internal haemorrhage ": 3.5998042139603865, "Intra-abdominal fluid collection ": 9.08150962349295, "Iron deficiency ": 2.4380643014211425, "Iron deficiency anaemia ": 5.241081661584681, "Left ventricular failure ": 12.504269814102663, "Liver transplant ": 12.583385700327966, "Localised infection ": 2.3605882940444314, "Lung disorder ": 2.10289114582812, "Lung transplant ": 114.28771266575342, "Mechanical ventilation ": 2.350065859815498, "Medical device change ": 75.4139689515332, "Mineral supplementation ": 62.02983418708365, "Multiple allergies ": 2.6988065021335736, "Multiple organ dysfunction syndrome ": 2.115070514807774, "N-terminal prohormone brain natriuretic peptide increased ": 7.347931725609952, "Nasal congestion ": 7.082429166701621, "Nasal dryness ": 2.3071541205084647, "Nasopharyngitis ": 2.012006443709877, "Oedema ": 6.015809866413793, "Oedema peripheral ": 5.1701702412845005, "Orthopnoea ": 6.6902349670391885, "Oxygen consumption increased ": 91.22856756866656, "Oxygen saturation abnormal ": 6.12531872656195, "Oxygen saturation decreased ": 10.51309914329442, "Oxygen therapy ": 13.125976067632, "Pain in jaw ": 18.829791754004464, "Palliative care ": 12.555415669859109, "Paracentesis ": 64.5026697992598, "Paranasal sinus discomfort ": 3.702123196102472, "Paranasal sinus hypersecretion ": 8.323526228462041, "Pericardial effusion ": 5.225951097576325, "Peripheral swelling ": 2.1505224748492897, "Platelet transfusion ": 26.24741529965362, "Pleural effusion ": 3.447341206646472, "Pneumonia ": 4.145584998703784, "Portal hypertension ": 4.102645259013127, "Portal hypertensive gastropathy ": 15.664425126822003, "Postoperative wound infection ": 2.066998286045499, "Procedural complication ": 8.669934685915337, "Product dose omission issue ": 4.517331757849565, "Product supply issue ": 2.055773797170493, "Productive cough ": 3.196057559369708, "Pulmonary alveolar haemorrhage ": 3.155913088536193, "Pulmonary arterial hypertension ": 140.53341881036673, "Pulmonary arterial pressure abnormal ": 43.99353773142183, "Pulmonary arterial pressure increased ": 71.29521420598124, "Pulmonary arterial wedge pressure increased ": 88.27062479916009, "Pulmonary artery dilatation ": 34.98929783412678, "Pulmonary congestion ": 4.969111585035855, "Pulmonary endarterectomy ": 300.32451154033663, "Pulmonary haemorrhage ": 2.559152180019192, "Pulmonary hypertension ": 31.738627186307436, "Pulmonary oedema ": 7.698999011975298, "Pulmonary thrombosis ": 2.9325382977160577, "Pulmonary veno-occlusive disease ": 50.883443068640695, "Pulseless electrical activity ": 4.8811637415524745, "Red blood cell transfusion ": 26.234829395404983, "Rehabilitation therapy ": 20.047142849401386, "Respiration abnormal ": 2.0070066495172165, "Respiratory failure ": 4.96909141395774, "Respiratory syncytial virus infection ": 3.478501779432178, "Respiratory tract congestion ": 4.499268914058862, "Respiratory tract infection viral ": 5.847635285556516, "Right ventricular dilatation ": 15.83053765456224, "Right ventricular dysfunction ": 28.88555525272328, "Right ventricular failure ": 87.0866361982028, "Right ventricular hypertrophy ": 7.783177629039145, "Right ventricular systolic pressure increased ": 29.219766772787864, "Scleroderma ": 25.40315210121928, "Seasonal allergy ": 5.242990050003099, "Secretion discharge ": 2.1248395664729496, "Sepsis ": 3.3349704607958963, "Sinus congestion ": 6.576406023088784, "Sinus disorder ": 2.505655099495208, "Skin infection ": 2.250306152536794, "Sluggishness ": 2.122619446410792, "Sputum discoloured ": 2.924145794291975, "Staphylococcal infection ": 2.5910246966929185, "Staphylococcus test positive ": 8.821875751609378, "Stent placement ": 2.8128606993852032, "Sudden death ": 3.044891098987419, "Surgery ": 3.232402278812138, "Systemic scleroderma ": 15.174113401869349, "Terminal state ": 12.696149308023712, "Therapy cessation ": 3.0212992698945387, "Therapy change ": 32.7635883429137, "Therapy interrupted ": 2.640663319889721, "Therapy non-responder ": 6.254385832795299, "Thrombosis in device ": 6.6578411475383925, "Thyroidectomy ": 7.010894529027608, "Tooth extraction ": 3.080356419027641, "Transfusion ": 33.65957397209331, "Transplant ": 33.65818563096437, "Transplant evaluation ": 193.74879499703025, "Treatment noncompliance ": 2.177255509881366, "Unevaluable event ": 8.768845752746968, "Upper respiratory tract infection ": 2.725388298052311, "Upper-airway cough syndrome ": 2.71857782432244, "Urine output decreased ": 2.6023575954063007, "Varices oesophageal ": 2.2180423716765003, "Vascular device infection ": 30.12499205922874, "Ventilation perfusion mismatch ": 80.47083746728701, "Viral infection ": 2.1651339600365325, "Walking distance test abnormal ": 85.663934882014, "Weight fluctuation ": 2.7702913851064896, "Weight increased ": 2.0678984805978127, "Wrong dose ": 5.009474933133349}
\ No newline at end of file
+{"Acute left ventricular failure": 891.8311966297554, "Acute myocardial infarction": 8.323788079628846, "Acute respiratory failure": 7.949871630144918, "Arrhythmia": 2.1637002606442524, "Blood glucose decreased": 3.954800841711125, "Blood glucose fluctuation": 5.801736209922603, "Blood glucose increased": 5.166667893991179, "Bronchitis": 4.138543535494864, "Cardiac disorder": 3.4550616560584406, "Cardiac failure": 46.55631311446894, "Cardiac failure acute": 18.328812141772666, "Cardiac failure congestive": 65.80370634287009, "Cardiomyopathy": 16.35629485735435, "Cardiovascular disorder": 56.45751122080873, "Cholelithiasis": 3.501837010707145, "Chronic left ventricular failure": 1410.3886988342722, "Chronic obstructive pulmonary disease": 2.5208491743472883, "Coronary artery disease": 21.52815461128047, "Diabetes mellitus": 4.606209068461874, "Dyspepsia": 3.72242112220773, "Glycosylated haemoglobin increased": 8.674524125061561, "Hyperglycaemia": 2.9168262852476614, "Hyperlipidaemia": 5.668924786666238, "Hypertensive heart disease": 89.10909366480809, "Hypoglycaemia": 2.1382084243749944, "Hypoglycaemic coma": 4.400593851614851, "Intentional product misuse": 4.727251592888439, "Left ventricular failure": 70.64423012632452, "Myocardial infarction": 6.590586636395497, "Pancreatic carcinoma": 10.470210013694052, "Pancreatitis": 14.258198894708364, "Pancreatitis acute": 18.78576684086436, "Pemphigoid": 30.333624450156545, "Product dose omission issue": 3.463996280201897, "Renal disorder": 2.805137489676003, "Respiratory failure": 2.1984272934319566, "Type 2 diabetes mellitus": 6.253683177396747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/816.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/816.json
index 2e566c85668..6d059f5b90b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/816.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/816.json
@@ -1 +1 @@
-{"Amputation ": 16.186119085325508, "Anhedonia ": 15.623318961576356, "Anxiety ": 6.389095637480471, "Arteriosclerosis ": 2.02031240214266, "Arthralgia ": 2.0657666519954696, "Asthenia ": 2.460998829277388, "Atelectasis ": 2.6281904096161006, "Atrophy ": 6.205003088637609, "Bacteraemia ": 2.5540368463330205, "Bone pain ": 2.506116327897064, "Burning sensation ": 22.480802468608324, "Carotid artery stenosis ": 4.771383072175496, "Confusional state ": 5.433235245456891, "Contrast media deposition ": 2286.1969330859497, "Decubitus ulcer ": 4.025311048765015, "Deformity ": 89.81360511996223, "Depression ": 2.185588670295014, "Dermatitis ": 3.329213697806414, "Device related infection ": 2.2342150366310363, "Dry skin ": 9.036452805451052, "Dysstasia ": 4.655357901249502, "Emotional distress ": 16.79590190336354, "End stage renal disease ": 2.0599429233168194, "Endocardial fibrosis ": 198.569371909976, "Exfoliative rash ": 27.09456818059071, "Extremity contracture ": 393.88532200964505, "Fibrosis ": 289.6170777983042, "Gadolinium deposition disease ": 3836.558883516212, "Gait disturbance ": 2.923623985302247, "Gait inability ": 4.764938781471843, "Gangrene ": 3.024234135694025, "General physical health deterioration ": 10.53851785969158, "Grip strength decreased ": 2.8069519582839337, "Hyperkeratosis ": 16.368438239246608, "Hypervolaemia ": 3.722330189238125, "Hypoaesthesia ": 7.065726247848556, "Immobile ": 3.136138345715496, "Impaired gastric emptying ": 2.3389550206460554, "Induration ": 8.037262269118271, "Inflammation ": 20.186883162162324, "Injury ": 49.84857623410041, "Joint contracture ": 465.8843764682989, "Joint instability ": 14.767543283681883, "Joint lock ": 16.027510860816882, "Joint range of motion decreased ": 72.14303258211316, "Joint stiffness ": 31.912287800336237, "Left ventricular hypertrophy ": 3.5895976354178023, "Leg amputation ": 4.503459517076035, "Lichenification ": 45.30524993893318, "Ligament disorder ": 39.14153631062759, "Limb mass ": 8.983798875109375, "Livedo reticularis ": 6.388184635194754, "Loss of control of legs ": 5.04898358831433, "Macule ": 2.802642456092703, "Mass ": 120.83878278883608, "Mental impairment ": 24.285711687637445, "Mental status changes ": 30.643123341667888, "Mobility decreased ": 28.04932357926465, "Motor dysfunction ": 8.128637198305313, "Movement disorder ": 16.99093514477029, "Muscle atrophy ": 2.7015857282212723, "Muscle contractions involuntary ": 2.1274734560659434, "Muscle contracture ": 57.46387176007076, "Muscle fatigue ": 3.4142423782617337, "Muscle fibrosis ": 190.51015348922263, "Muscle spasms ": 7.797043518152326, "Muscle tightness ": 14.429060955606436, "Muscular weakness ": 4.3130281200882346, "Musculoskeletal disorder ": 2.254740944591571, "Musculoskeletal stiffness ": 6.461734883825051, "Myocardial fibrosis ": 11.17510169807368, "Myosclerosis ": 136.6886234996496, "Nephrogenic systemic fibrosis ": 639.5132296893016, "Neuropathic arthropathy ": 19.30969205579556, "Nodule ": 2.628598509815405, "Ocular icterus ": 8.606465085381101, "Oedema ": 2.9731341476076505, "Oedema peripheral ": 7.379097580892623, "Onychomadesis ": 3.5367906725961964, "Osteomyelitis ": 3.578151098040038, "Pain ": 4.629547651816242, "Pain of skin ": 8.872682436509104, "Papule ": 3.125187504547718, "Paraesthesia ": 4.294114252058795, "Peau d'orange ": 1367.7014714439697, "Peripheral ischaemia ": 3.960055522563656, "Peroneal nerve palsy ": 3.9354419225954103, "Pigmentation disorder ": 8.106690691395034, "Plantar fasciitis ": 5.216795573526623, "Post inflammatory pigmentation change ": 43.121424622012185, "Product prescribing error ": 2.0259540127447817, "Quality of life decreased ": 10.337816255591784, "Rash ": 2.281202288059592, "Rash macular ": 3.5487802114495945, "Rash papular ": 4.7982762713513845, "Scab ": 3.652320539124522, "Scar ": 103.21371493084332, "Sclerodactylia ": 243.49001473448632, "Scleroderma ": 9.518087790306872, "Skin abrasion ": 6.947744541526506, "Skin atrophy ": 22.917234094784803, "Skin burning sensation ": 4.085533061709405, "Skin discolouration ": 19.06909304230157, "Skin disorder ": 10.175293435584846, "Skin exfoliation ": 7.965240173412081, "Skin fibrosis ": 1003.5737319449272, "Skin fissures ": 10.138605314112649, "Skin hyperpigmentation ": 98.62015591298464, "Skin hypertrophy ": 432.90689983110553, "Skin hypopigmentation ": 38.29635548342187, "Skin induration ": 465.0880855715105, "Skin lesion ": 11.374394007831654, "Skin mass ": 15.225302075083167, "Skin necrosis ": 4.203269806868773, "Skin oedema ": 6.21524085008329, "Skin plaque ": 41.0394106745083, "Skin swelling ": 30.4873981787522, "Skin tightness ": 376.8937778286475, "Skin ulcer ": 9.160464757448402, "Skin warm ": 2.7263703657254266, "Skin wrinkling ": 12.567536580225786, "Soft tissue disorder ": 19.112653642371285, "Staphylococcal sepsis ": 2.573547081837788, "Stasis dermatitis ": 27.675873345745696, "Tendon disorder ": 3.5843842753130137, "Ulcer ": 2.368667764915237, "Wheelchair user ": 9.718743097686168, "Xerosis ": 27.82084979076061}
\ No newline at end of file
+{"Diarrhoea": 9.419745687894466, "Nausea": 2.100987631800856, "Neutropenia": 13.198894444025408, "Off label use": 2.692221815925102}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/817.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/817.json
index a5c53a58567..166823640af 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/817.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/817.json
@@ -1 +1 @@
-{"Diabetes mellitus inadequate control ": 140.78213247575314, "Glycosylated haemoglobin increased ": 126.52260579786405}
\ No newline at end of file
+{"Drug interaction": 22.434415304983077}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/818.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/818.json
index c50bbb02c8a..e85a9276275 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/818.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/818.json
@@ -1 +1 @@
-{"Drug interaction ": 13.433001069674203}
\ No newline at end of file
+{"Abdominal pain": 2.6569679122568943, "Anaemia": 5.872784722671446, "Asthenia": 2.8678247352553257, "Diarrhoea": 8.2898943300861, "Erythema": 3.246147991821441, "Neutropenia": 5.323564727147221, "Paraesthesia": 7.451758176993669, "Pruritus": 2.738356950750563}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/819.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/819.json
index 0f3446efff4..c6ae6272362 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/819.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/819.json
@@ -1 +1 @@
-{"Arthritis ": 3.443238462424279, "Arthropathy ": 2.3308015051993154, "Back pain ": 2.4096132842581617, "Blood pressure systolic increased ": 14.86984103462028, "Bronchitis ": 6.544003010432597, "Bursitis ": 12.21398946587801, "Cellulitis ": 5.055185786478892, "Coeliac disease ": 19.939869933649923, "Constipation ": 2.3500809979590622, "Contraindicated product administered ": 3.857741509304713, "Cystitis ": 7.194059560977343, "Drug hypersensitivity ": 8.396550816373425, "Drug ineffective ": 2.7478270399802107, "Fine motor skill dysfunction ": 59.64259648944277, "Fluid retention ": 21.144083904748868, "Food allergy ": 59.89588168216377, "Gait disturbance ": 3.204433564804455, "Gastric ulcer ": 11.331536926191276, "Heart rate decreased ": 7.639315555863181, "Hepatic enzyme increased ": 7.180405049501145, "Hyperhidrosis ": 2.060605839325512, "Hypersensitivity ": 3.0147967468381345, "Immunodeficiency ": 41.19538630829245, "Infusion related reaction ": 5.1587347396241885, "Injection site induration ": 10.478637025516663, "Instillation site inflammation ": 5488.458910089917, "Intervertebral disc protrusion ": 16.25229229033568, "Joint dislocation ": 25.12274136452823, "Joint effusion ": 35.654266509805666, "Joint swelling ": 2.9086239638211517, "Lethargy ": 2.4940697925235287, "Memory impairment ": 2.084766456628006, "Nasopharyngitis ": 2.1688320068792786, "Osteoarthritis ": 11.016220108711304, "Product use issue ": 2.784619438870995, "Rash erythematous ": 6.495387841387592, "Rheumatoid arthritis ": 11.052196031653216, "Temperature regulation disorder ": 53.63763133864882, "Treatment failure ": 6.598547505570691, "Upper respiratory tract infection ": 21.531977178920023, "Urinary retention ": 2.2328524441611832, "Urinary tract infection ": 2.6792868190187065, "Vascular pain ": 54.5145175641762, "Viral infection ": 10.36460480020837, "Vitamin C decreased ": 2771.332428029834, "Vitamin D decreased ": 49.84455832493192}
\ No newline at end of file
+{"Eye irritation": 91.33153698774557, "Eye pain": 21.302859423327806, "Eye pruritus": 79.82687449024846, "Eye swelling": 22.69356933040864, "Hypersensitivity": 2.8629856762911507, "Lacrimation increased": 52.36524843309823, "Ocular hyperaemia": 43.74035806725436, "Pruritus": 2.1321789817860743, "Vision blurred": 10.786548381990274, "Visual impairment": 5.85637179482383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/82.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/82.json
index eb1866e08c1..6c1714f7c2d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/82.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/82.json
@@ -1 +1 @@
-{"Toxicity to various agents ": 87.93454386707116}
\ No newline at end of file
+{"Acute respiratory distress syndrome": 2.085089840636897, "Antineutrophil cytoplasmic antibody positive": 334.82379520779006, "Anxiety": 4.184483921032506, "Arteriosclerosis": 94.04125245024495, "Arteriosclerosis coronary artery": 134.87173287386997, "Asthma": 9.535597473530563, "Asthma-chronic obstructive pulmonary disease overlap syndrome": 45.98258184337311, "Breast conserving surgery": 25.04691404904983, "Bronchiectasis": 8.991435254329664, "Bronchitis": 2.2137365910200764, "Bronchospasm paradoxical": 28.004217501239417, "Candida infection": 5.038645786684179, "Capillaritis": 340.92076466197153, "Cardiac murmur": 3.4606675284303416, "Cardiac pacemaker insertion": 4.870767357536254, "Choking": 5.440132286604418, "Chronic obstructive pulmonary disease": 16.103298671033716, "Condition aggravated": 7.0194853904592005, "Conjunctivitis allergic": 501.8586392072335, "Contraindicated product prescribed": 16.00492877015562, "Cough": 2.510581247439032, "Dust allergy": 778.5265350418694, "Dysphonia": 2.4291229468287776, "Dyspnoea": 3.668002020155052, "Dyspnoea exertional": 2.233586478772062, "Dysuria": 2.4431385863607664, "Emphysema": 11.374434353079742, "Eosinophilic granulomatosis with polyangiitis": 163.87951462525564, "Expired product administered": 2.292434119589378, "Eye disorder": 3.447257683678464, "Forced expiratory volume decreased": 131.2388577090135, "Full blood count abnormal": 35.224706129151855, "Glaucoma": 3.4749107087156177, "Haemoptysis": 38.17418876090326, "Hospitalisation": 2.3189500030345624, "Hypomania": 6.455445180043111, "Hypothyroidism": 17.998906336397237, "Hypoxia": 29.44448850019058, "Ill-defined disorder": 3.007246428613916, "Inability to afford medication": 10.106397769075995, "Jaundice cholestatic": 5.675143719615152, "Labelled drug-drug interaction medication error": 3.282906298825487, "Loss of personal independence in daily activities": 17.518069261422145, "Lower respiratory tract infection": 2.043247619570736, "Lung disorder": 28.637294936027303, "Lung neoplasm malignant": 9.88570216641368, "Mite allergy": 803.6621048435467, "Mycotic allergy": 1029.335445414839, "Nasal congestion": 2.2811884820310686, "Nasal polyps": 7.376806018305943, "Neoplasm malignant": 2.0337387666960214, "Neuritis": 304.741275491901, "Neurological symptom": 136.9654211957681, "Nodule": 85.73532531818536, "Normochromic normocytic anaemia": 386.3410094888442, "Obstruction": 14.585760046753316, "Obstructive airways disorder": 67.17227073171374, "Oral candidiasis": 5.599558497368258, "Oral pain": 2.1225586142702206, "Oxygen therapy": 10.73050880517652, "Pain in extremity": 2.044982819298563, "Pneumonia": 3.6853610342420335, "Product complaint": 8.609315683185786, "Product dispensing error": 3.1323630042090533, "Product dose omission issue": 2.798146817145694, "Product prescribing issue": 6.289135674421059, "Product use in unapproved indication": 2.415338084373309, "Productive cough": 30.195563057228767, "Pulmonary alveolar haemorrhage": 150.9443917057108, "Pulmonary congestion": 2.913883770873646, "Pulmonary embolism": 7.344083260581602, "Pulmonary fibrosis": 46.04009724517306, "Pulmonary mass": 2.2727299723518404, "Pulmonary resection": 132.97758905116666, "Pulmonary vasculitis": 1051.319867986339, "Respiratory disorder": 3.073818100741375, "Respiratory symptom": 199.92470116922703, "Rhinitis allergic": 4.193257042989371, "Rhinorrhoea": 2.513492137373364, "Sarcoidosis": 5.200121920024449, "Schizophrenia": 3.9019599376997456, "Sinus disorder": 6.186830362960381, "Sinusitis": 2.0924156276719623, "Sleep disorder due to a general medical condition": 8.867796623997487, "Therapeutic product effect incomplete": 3.78525791044472, "Therapy cessation": 3.9640556405171616, "Total lung capacity increased": 60.44459068687416, "Treatment noncompliance": 2.298776222213451, "Urinary retention": 6.200385379785451, "Vasculitis": 4.829891293210546, "Wheezing": 5.523926426806713, "Wrong technique in device usage process": 22.184309370255598}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/820.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/820.json
index 8a5a2aabbce..ff8d50adf4e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/820.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/820.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 3.942073738760807, "Abdominal distension ": 10.029114237798856, "Abdominal pain ": 4.732635404329264, "Abdominal pain lower ": 23.462033419613583, "Abortion spontaneous ": 23.42208079717694, "Ascites ": 102.59086172730392, "Haematocrit increased ": 161.93228765978904, "Incorrect route of product administration ": 21.48588750191, "Ovarian hyperstimulation syndrome ": 2249.0641223469383, "Overdose ": 5.858271996896808, "Pelvic fluid collection ": 925.225940880982, "Pleural effusion ": 9.870513781926528}
\ No newline at end of file
+{"Addison's disease": 10.721286382533403, "Adrenal disorder": 24.177262636318197, "Adrenal insufficiency": 89.26868147766206, "Adrenocortical insufficiency acute": 27.73348853346601, "Adrenocorticotropic hormone deficiency": 314.68175790908253, "Alanine aminotransferase increased": 2.1454070062029933, "Amylase increased": 4.95806308725641, "Aspartate aminotransferase increased": 2.3023644968115566, "Autoimmune colitis": 95.6025489184596, "Autoimmune dermatitis": 78.15567788188058, "Autoimmune haemolytic anaemia": 4.155068233475303, "Autoimmune hepatitis": 26.58098832801254, "Autoimmune nephritis": 37.69317824285383, "Autoimmune pancreatitis": 41.17946796875452, "Autoimmune thyroiditis": 10.513798600314455, "Blood corticotrophin decreased": 62.27091645409207, "Blood creatine phosphokinase increased": 2.1419227580911206, "Blood thyroid stimulating hormone abnormal": 19.05353379167592, "Blood thyroid stimulating hormone decreased": 10.746159253462151, "Blood thyroid stimulating hormone increased": 2.940238192872663, "Brain oedema": 2.2233192991500506, "Bronchopulmonary aspergillosis": 2.852820722390136, "C-reactive protein increased": 2.6225406050329614, "Central hypothyroidism": 26.05312368843499, "Cholangitis": 9.07120859395352, "Cholangitis sclerosing": 18.55649613057516, "Cholecystitis": 2.9151497116995624, "Cholestasis": 2.398980272128844, "Chronic gastritis": 3.407306997076868, "Colitis": 37.01876210175181, "Colitis microscopic": 5.047996020770578, "Coronavirus infection": 3.072776966096285, "Cortisol decreased": 17.502826210074264, "Cytokine release syndrome": 11.937667423042948, "Cytomegalovirus enterocolitis": 13.245436749455424, "Decreased appetite": 2.909912975254876, "Dermatitis": 4.014861616193892, "Dermatitis psoriasiform": 6.18950933479755, "Diabetic ketoacidosis": 3.257024816621925, "Diarrhoea": 2.0473042002501045, "Disseminated intravascular coagulation": 6.33840348610658, "Drug eruption": 5.390890298927222, "Drug-induced liver injury": 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disorder": 206.16830038711043, "Immune-mediated hepatitis": 99.53363435730144, "Immune-mediated hyperthyroidism": 59.723152833924566, "Immune-mediated hypophysitis": 136.43005773823856, "Immune-mediated hypothyroidism": 55.93186619878118, "Immune-mediated lung disease": 152.35088760516322, "Immune-mediated myasthenia gravis": 37.014866421035, "Immune-mediated myocarditis": 71.98375210372812, "Immune-mediated myositis": 53.16995419712262, "Immune-mediated nephritis": 108.7827885815122, "Immune-mediated neuropathy": 37.32379813315822, "Immune-mediated pancreatitis": 105.10613000328917, "Immune-mediated renal disorder": 98.88086835554972, "Immune-mediated thyroiditis": 85.8837163156792, "Immune-mediated uveitis": 54.84933703834195, "Infectious pleural effusion": 7.630901397794385, "Infusion related reaction": 2.671359213541632, "Intentional product use issue": 16.126217029358234, "Interstitial lung disease": 15.237270037331374, "Intestinal perforation": 3.459910889222848, "Large intestine perforation": 3.873264263300012, "Leukoderma": 230.95446120214768, "Lichenoid keratosis": 6.208279406740189, "Lipase increased": 3.2232245572285403, "Liver disorder": 11.26697223504703, "Lung opacity": 4.340232951173019, "Lymphangiosis carcinomatosa": 11.343486180993914, "Lymphocytic hypophysitis": 110.31049889217404, "Malignant neoplasm progression": 25.993291592963157, "Malignant pleural effusion": 7.970671401605895, "Meningitis": 4.957867972420475, "Meningitis aseptic": 9.269458446645515, "Metastases to bone": 3.940960003961727, "Metastases to central nervous system": 13.022718873683932, "Metastases to liver": 3.0259874143756504, "Metastases to lung": 3.818139964867101, "Metastases to lymph nodes": 4.581561098716215, "Metastases to meninges": 5.882507387465225, "Metastases to spine": 6.397980894324145, "Metastatic malignant melanoma": 3.885011201384616, "Myasthenia gravis": 22.258222480237016, "Myasthenic syndrome": 9.244769872030815, "Myocarditis": 6.062662293770092, "Myositis": 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4.195065923211207, "Prescribed underdose": 4.590715224437839, "Primary adrenal insufficiency": 35.38583373398441, "Primary hypothyroidism": 32.870005717940174, "Pulmonary toxicity": 15.986156831300322, "Radiation pneumonitis": 32.73041213859531, "Rash": 2.5183700269706653, "Rash maculo-papular": 2.797687070726397, "Renal disorder": 2.8576307290107894, "Renal impairment": 2.1334675891689945, "Sarcoidosis": 3.400919556746724, "Secondary adrenocortical insufficiency": 214.4315939123931, "Sialoadenitis": 10.437767186324118, "Silent thyroiditis": 185.3268309983824, "Sjogren's syndrome": 3.701618463095721, "Skin disorder": 7.958009716743746, "Skin toxicity": 5.198866120923339, "Steroid diabetes": 7.85353687757981, "Stevens-Johnson syndrome": 2.238393996782843, "Thrombophlebitis migrans": 42.0414189899959, "Thyroid disorder": 13.751972503811968, "Thyroiditis": 65.88600664414933, "Thyroiditis subacute": 7.0407337600354944, "Thyrotoxic crisis": 12.941417456050493, "Toxic epidermal necrolysis": 2.503009088371614, "Troponin increased": 2.364477633319907, "Tubulointerstitial nephritis": 9.04539935680851, "Tumour haemorrhage": 7.962916417110066, "Tumour lysis syndrome": 4.7530033151256585, "Tumour pseudoprogression": 62.74309221286461, "Type 1 diabetes mellitus": 21.305147466049306, "Uveitis": 7.802749831210593, "Vitiligo": 11.99276302293395, "Vogt-Koyanagi-Harada disease": 39.36864820526257}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/821.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/821.json
index dbbb57c185f..a7ffb0481da 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/821.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/821.json
@@ -1 +1 @@
-{"Asthenia ": 4.496947953687483, "Hot flush ": 32.71852701561732}
\ No newline at end of file
+{"Drug abuse": 90.323352896149}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/822.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/822.json
index bea2968cf46..f016b3b9f23 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/822.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/822.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 4.888808557175275, "Aspartate aminotransferase increased ": 5.5892127013615776, "Bacterial infection ": 4.663154745259368, "Blood creatine phosphokinase increased ": 5.952503525734808, "Bronchiectasis ": 13.967229476221178, "Bronchopulmonary aspergillosis allergic ": 84.25134927806295, "Bronchospasm ": 5.628203537675902, "Chest discomfort ": 4.254297981532559, "Cough ": 2.8880749075372667, "Cystic fibrosis ": 856.1778460442332, "Cystic fibrosis lung ": 1762.147212870255, "Cystic fibrosis respiratory infection suppression ": 4273.055114918833, "Distal intestinal obstruction syndrome ": 172.42963801666235, "Dyspnoea ": 2.0356061306450983, "Emotional disorder ": 5.099836298815795, "Failure to thrive ": 14.970730733254054, "Forced expiratory volume decreased ": 210.98520079574155, "Haemoptysis ": 13.127019942616585, "Hepatic cytolysis ": 3.0588832808065307, "Hepatic enzyme increased ": 2.7717948960003884, "Hospitalisation ": 40.20109797178514, "Illness ": 3.112634432889556, "Increased bronchial secretion ": 40.84965511716271, "Infection ": 13.5450673932968, "Infective pulmonary exacerbation of cystic fibrosis ": 2780.692803587542, "Influenza ": 4.422379182610666, "Intestinal obstruction ": 12.892589610542563, "Liver function test increased ": 4.7155056174303445, "Lower respiratory tract infection ": 2.3053675980509354, "Lung disorder ": 5.239077716003076, "Lung transplant ": 112.21702162275216, "Mood swings ": 3.379896707076513, "Nasal congestion ": 2.2737378618230006, "Nasopharyngitis ": 2.8936978937871003, "Pneumonia ": 7.335855264313565, "Pneumonia pseudomonal ": 37.72375508149661, "Pneumonia staphylococcal ": 34.55838598085397, "Pneumothorax ": 13.334877501826746, "Productive cough ": 6.474440952637258, "Pseudomonas infection ": 59.52932317879984, "Pulmonary function test decreased ": 366.0563109608832, "Rales ": 6.697439608737049, "Respiration abnormal ": 45.7458022871807, "Respiratory disorder ": 3.1851075493451675, "Respiratory failure ": 3.851561895345722, "Respiratory symptom ": 23.92436941742956, "Respiratory syncytial virus infection ": 10.525695005938278, "Respiratory tract infection ": 5.24819095864479, "Rhinovirus infection ": 27.60171613281335, "Sinus disorder ": 7.228140265439216, "Sinus operation ": 148.9677654427281, "Sinusitis ": 4.463458862366823, "Sputum increased ": 47.25802614294438, "Staphylococcal infection ": 12.543138387665088, "Stenotrophomonas infection ": 40.120419749451166, "Surgery ": 4.970935843249374, "Transaminases increased ": 3.7718442755605537, "Treatment noncompliance ": 10.250656578709323, "Upper limb fracture ": 4.906698835782488, "Upper respiratory tract infection ": 2.2518345110030458, "Viral infection ": 9.85631440855826, "Weight decreased ": 2.493544631029533, "Wheezing ": 2.113947201904041}
\ No newline at end of file
+{"Drug withdrawal syndrome neonatal": 140.61201824392026, "Exposure via breast milk": 155.96923786553293, "Foetal exposure during pregnancy": 29.85030895051288, "Premature baby": 39.337907723587456}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/823.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/823.json
index 46769b5ea63..04ad4a47c0d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/823.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/823.json
@@ -1 +1 @@
-{"Abdominal pain ": 3.500259164438527, "Drug interaction ": 16.37897112555646, "Renal impairment ": 15.060810848822332}
\ No newline at end of file
+{"Cardio-respiratory arrest": 150.16074822092176, "Completed suicide": 119.96856128627208, "Death": 16.92783660823521, "Drug abuse": 43.20457782376957, "Respiratory arrest": 54.78702525440836, "Toxicity to various agents": 19.32159908955936}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/824.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/824.json
index 5b40d9539d7..6a681cffe6d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/824.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/824.json
@@ -1 +1 @@
-{"Condition aggravated ": 2.681991856107963, "Drug ineffective ": 3.390188248075743, "Drug interaction ": 3.3406336642954604, "Drug resistance ": 10.3997089083515, "Drug-induced liver injury ": 5.065667845388361, "Electrocardiogram QT prolonged ": 3.324427897010496, "Enterocolitis haemorrhagic ": 68.26254035280253, "Erythema multiforme ": 6.166523403500603, "Exposure during pregnancy ": 3.010433366954093, "Foetal death ": 14.3726956600107, "Foetal exposure during pregnancy ": 14.20124506709699, "Foetal growth restriction ": 29.65656131696017, "Hallucination ": 4.045122864211468, "Hypoxia ": 8.192240618259053, "International normalised ratio increased ": 11.203657936697203, "Low birth weight baby ": 19.508678938503497, "Maternal exposure during pregnancy ": 11.32997835754546, "Pathogen resistance ": 108.42485152512316, "Premature baby ": 10.947227006336307, "Premature delivery ": 42.38847643028049, "Rash ": 2.3840113288488904, "Rash maculo-papular ": 2.6586810172186124, "Respiratory distress ": 5.061032356298201, "Respiratory failure ": 4.056748317554191, "Rhabdomyolysis ": 2.967152912319696, "Stevens-Johnson syndrome ": 4.290335738141466, "Stillbirth ": 70.6872639638126, "Swelling face ": 2.0656423248005717, "Toxic epidermal necrolysis ": 7.349449915721306}
\ No newline at end of file
+{"Accidental overdose": 16.81550769169097, "Cardio-respiratory arrest": 12.917513539631653, "Completed suicide": 13.00993482950356, "Death": 2.390661946630833, "Drug abuse": 32.69048150657904, "Drug dependence": 30.465534988836197, "Drug screen positive": 169.0674731848615, "Drug withdrawal syndrome": 27.80155307735634, "Drug withdrawal syndrome neonatal": 121.97395366582086, "Exposure via breast milk": 51.87075023362419, "Foetal exposure during pregnancy": 14.90641647128799, "Intentional overdose": 7.009035091167111, "Jaundice neonatal": 117.36398677284554, "Loss of consciousness": 2.408634594748143, "Maternal exposure during pregnancy": 3.468688777077636, "Overdose": 14.344372271990986, "Product preparation issue": 72.06738655976147, "Product use issue": 3.147240815027134, "Somnolence": 2.1605383531797075, "Substance abuse": 107.88791336990845, "Toxicity to various agents": 11.557335086071468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/825.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/825.json
index 3c722765926..61c9ebc9718 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/825.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/825.json
@@ -1 +1 @@
-{"Acquired gene mutation ": 1267.3087728740286, "Cardiac failure ": 4.929872617388778, "Cardiomyopathy ": 6.939818742311763, "Cardiotoxicity ": 26.771586678691445, "Deep vein thrombosis ": 3.057609333367075, "Disease progression ": 5.982463005698374, "Drug resistance ": 104.07428461205674, "EGFR gene mutation ": 812.9786154550924, "Electrocardiogram QT prolonged ": 5.64770763476954, "Interstitial lung disease ": 16.746301250464988, "Malignant neoplasm progression ": 46.0742427092143, "Malignant transformation ": 887.0728703677532, "Metastases to bone ": 19.71399934239578, "Metastases to central nervous system ": 67.20668007534422, "Metastases to liver ": 20.23584385119665, "Metastases to lung ": 20.150139670735104, "Metastases to lymph nodes ": 19.914064423452132, "Metastases to meninges ": 313.46420020359267, "Metastasis ": 21.220950133878887, "Mucosal inflammation ": 9.77079322761784, "Myelosuppression ": 3.9137885572720768, "Off label use ": 2.22759611665831, "Paronychia ": 101.30965749809664, "Platelet count decreased ": 2.479700193737973, "Pleural effusion ": 6.853987656099673, "Pneumonitis ": 53.44695903828789, "Pulmonary embolism ": 4.272548256537188, "Respiratory failure ": 4.806542988183671, "Skin toxicity ": 23.41604806846981, "Thrombocytopenia ": 4.565497674625321, "Torsade de pointes ": 9.240178552416998}
\ No newline at end of file
+{"Abdominal cavity drainage": 58.93192408452042, "Abdominal distension": 2.410752426522828, "Acute respiratory failure": 6.6264703053417975, "Adverse event": 2.327185556149768, "Anaemia": 2.272288631361746, "Angioplasty": 6.683211649594256, "Aortic stenosis": 2.293622335142404, "Appendicectomy": 3.613363044113746, "Application site irritation": 2.9149350982591145, "Ascites": 4.27093406355438, "Aspiration pleural cavity": 24.125080507302645, "Atrial flutter": 6.171882961567687, "Atrial septal defect repair": 75.07100072061395, "Atrial tachycardia": 2.246824754712711, "Bacteraemia": 3.046115926555548, "Biopsy lung": 27.35997909895862, "Blood culture negative": 79.29069045120157, "Blood culture positive": 17.566327355683875, "Blood iron decreased": 6.605909893713177, "Blood magnesium decreased": 3.040348525180184, "Blood potassium decreased": 3.307825617551852, "Brain natriuretic peptide increased": 18.8190142438238, "Brain operation": 4.8888837326999655, "Bronchitis": 2.8456102139492803, "Cardiac ablation": 11.327414896630604, "Cardiac failure": 5.410756416358564, "Cardiac failure acute": 3.358787067025721, "Cardiac failure congestive": 4.205535783466857, "Cardiac failure high output": 42.56940276906448, "Cardiac operation": 9.172735993689244, "Cardiac output increased": 52.07591617029961, "Cardiac pacemaker insertion": 7.808743912822477, "Cardiopulmonary failure": 2.231243003460801, "Cardiovascular insufficiency": 2.354962556986151, "Cardioversion": 6.7311624215253865, "Catheter management": 215.5749899042078, "Catheter placement": 51.98702951620403, "Catheter removal": 45.29965394003322, "Catheter site discharge": 87.14104146174087, "Catheter site discolouration": 158.10465886858586, "Catheter site erythema": 88.62557391079936, "Catheter site haemorrhage": 34.062850745114886, "Catheter site infection": 66.02385597740883, "Catheter site irritation": 136.49071520517364, "Catheter site pain": 66.76169163414067, "Catheter site pruritus": 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tolerance decreased": 2.081498638341815, "Eye operation": 2.902301506951632, "Fall": 2.10907118011471, "Fluid retention": 27.25107927502274, "Flushing": 3.905599911375029, "Gallbladder disorder": 2.1531805407849545, "Gastroenteritis viral": 3.640769655976606, "Gastrointestinal tube insertion": 3.634211268457672, "Generalised oedema": 2.2567136023540724, "Haematocrit decreased": 3.69095576008058, "Haemodialysis": 4.523628767791503, "Haemoglobin decreased": 3.588916916278228, "Haemoptysis": 3.1420601104483192, "Head injury": 2.100899907781085, "Heart and lung transplant": 116.40019806549728, "Heart transplant": 15.580110357731838, "Hepatic cirrhosis": 2.2097995958867704, "Hepatic enzyme abnormal": 2.013531734060102, "Hernia repair": 6.400596211561336, "Hip fracture": 2.880515850311754, "Hip surgery": 3.282301750001958, "Hospice care": 16.389299527296895, "Hospitalisation": 13.16808153641268, "Hypercapnia": 4.3349815533207385, "Hypervolaemia": 55.12319817743671, "Hypotension": 3.0480973359001715, "Hypoxia": 9.63506135045854, "Hysterectomy": 3.9693415931929272, "Idiopathic pulmonary fibrosis": 2.910931409694798, "Illness": 2.4231974123299547, "Increased bronchial secretion": 2.9273001865122685, "Infusion site erythema": 8.780897268907744, "Infusion site haemorrhage": 12.164491741736969, "Infusion site infection": 40.250713934014506, "Infusion site irritation": 29.90218666238063, "Infusion site pain": 17.137490491910704, "Infusion site pruritus": 9.687021743806795, "Infusion site swelling": 13.127551964363512, "Infusion site warmth": 21.852188937375036, "Internal haemorrhage": 3.5992951421387245, "Intra-abdominal fluid collection": 9.08022539009012, "Iron deficiency": 2.4377195306507677, "Iron deficiency anaemia": 5.238459160154789, "Left ventricular failure": 12.50250145772203, "Liver transplant": 12.581606206670688, "Localised infection": 2.3602544682784754, "Lung disorder": 2.102593743014016, "Lung transplant": 114.27154895923174, "Mechanical ventilation": 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transfusion": 26.24370354018031, "Pleural effusion": 3.446533786575484, "Pneumonia": 4.144998486406794, "Portal hypertension": 4.102065093365541, "Portal hypertensive gastropathy": 15.662210019454564, "Postoperative wound infection": 2.066705991246776, "Procedural complication": 8.668708634681412, "Product dose omission issue": 4.516692757192833, "Product supply issue": 2.055483088118628, "Productive cough": 3.195605543788275, "Pulmonary alveolar haemorrhage": 3.1554667951821656, "Pulmonary arterial hypertension": 140.51353714803545, "Pulmonary arterial pressure abnormal": 43.98731657451353, "Pulmonary arterial pressure increased": 71.28513139714747, "Pulmonary arterial wedge pressure increased": 88.2581423878588, "Pulmonary artery dilatation": 34.98434995713723, "Pulmonary congestion": 4.968408846512941, "Pulmonary endarterectomy": 300.28204308032525, "Pulmonary haemorrhage": 2.5587902781767435, "Pulmonary hypertension": 31.73413759343223, "Pulmonary oedema": 7.696881425543332, "Pulmonary thrombosis": 2.932123591514781, "Pulmonary veno-occlusive disease": 50.87624731714959, "Pulseless electrical activity": 4.880473474470437, "Red blood cell transfusion": 26.231119369316023, "Rehabilitation therapy": 20.04430785900896, "Respiration abnormal": 2.0067228312096104, "Respiratory failure": 4.967973681548554, "Respiratory syncytial virus infection": 3.4780098603198635, "Respiratory tract congestion": 4.498632647076335, "Respiratory tract infection viral": 5.846808365901286, "Right ventricular dilatation": 15.828299040356326, "Right ventricular dysfunction": 28.881470385082352, "Right ventricular failure": 87.07431777768922, "Right ventricular hypertrophy": 7.782077008442995, "Right ventricular systolic pressure increased": 29.215634809565817, "Scleroderma": 25.399559518120125, "Seasonal allergy": 5.242248597347933, "Secretion discharge": 2.124539085548492, "Sepsis": 3.3344987549283496, "Sinus congestion": 6.575476006920368, "Sinus disorder": 2.5053007648137733, "Skin infection": 2.24998793086501, "Sluggishness": 2.12231928062709, "Sputum discoloured": 2.9237322777121864, "Staphylococcal infection": 2.5906582719453186, "Staphylococcus test positive": 8.820628223111724, "Stent placement": 2.8124629201239144, "Sudden death": 3.0444604922469, "Surgery": 3.2319451421147005, "Systemic scleroderma": 15.17196759879407, "Terminal state": 12.694353837942352, "Therapy cessation": 3.0208720136691154, "Therapy change": 32.75895478101228, "Therapy interrupted": 2.640289889914358, "Therapy non-responder": 6.252947058722966, "Thrombosis in device": 6.656899641547017, "Thyroidectomy": 7.009903114418974, "Tooth extraction": 3.079920817825186, "Transfusion": 33.65481317051211, "Transplant": 33.653425722781826, "Transplant evaluation": 193.72139584448232, "Treatment noncompliance": 2.176947596948948, "Unevaluable event": 8.767605526365145, "Upper respiratory tract infection": 2.7250028648581077, "Upper-airway cough syndrome": 2.718193383967456, "Urine output decreased": 2.601989582441215, "Varices oesophageal": 2.2177287176972422, "Vascular device infection": 30.12073156580751, "Ventilation perfusion mismatch": 80.45945793203063, "Viral infection": 2.1648277687642583, "Walking distance test abnormal": 85.65182090258286, "Weight fluctuation": 2.7698996326763967, "Weight increased": 2.0676059932588378, "Wrong dose": 5.008766535083606}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/826.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/826.json
index 78f9563909d..7b10625c887 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/826.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/826.json
@@ -1 +1 @@
-{"Drug reaction with eosinophilia and systemic symptoms ": 36.90327943788094, "Pruritus ": 2.706152432639293}
\ No newline at end of file
+{"Amputation": 16.186119085325508, "Anhedonia": 15.623318961576356, "Anxiety": 6.389095637480471, "Arteriosclerosis": 2.02031240214266, "Arthralgia": 2.0657666519954696, "Asthenia": 2.4609005942345705, "Atelectasis": 2.6281904096161006, "Atrophy": 6.205003088637609, "Bacteraemia": 2.5540368463330205, "Bone pain": 2.506116327897064, "Burning sensation": 22.480802468608324, "Carotid artery stenosis": 4.771383072175496, "Confusional state": 5.433235245456891, "Contrast media deposition": 2286.1969330859497, "Decubitus ulcer": 4.025311048765015, "Deformity": 89.81360511996223, "Depression": 2.185588670295014, "Dermatitis": 3.328776148788992, "Device related infection": 2.2342150366310363, "Dry skin": 9.036452805451052, "Dysstasia": 4.65429154715601, "Emotional distress": 16.79590190336354, "End stage renal disease": 2.0599429233168194, "Endocardial fibrosis": 198.569371909976, "Exfoliative rash": 27.09456818059071, "Extremity contracture": 393.88532200964505, "Fibrosis": 289.6170777983042, "Gadolinium deposition disease": 3836.558883516212, "Gait disturbance": 2.9235707625020035, "Gait inability": 4.764938781471843, "Gangrene": 3.024234135694025, "General physical health deterioration": 10.53851785969158, "Grip strength decreased": 2.8069519582839337, "Hyperkeratosis": 16.368438239246608, "Hypervolaemia": 3.722330189238125, "Hypoaesthesia": 7.065726247848556, "Immobile": 3.136138345715496, "Impaired gastric emptying": 2.3389550206460554, "Induration": 8.037262269118271, "Inflammation": 20.185831095734184, "Injury": 49.840814630562114, "Joint contracture": 465.8843764682989, "Joint instability": 14.767543283681883, "Joint lock": 16.027510860816882, "Joint range of motion decreased": 72.14303258211316, "Joint stiffness": 31.912287800336237, "Left ventricular hypertrophy": 3.5895976354178023, "Leg amputation": 4.503459517076035, "Lichenification": 45.30524993893318, "Ligament disorder": 39.14153631062759, "Limb mass": 8.983798875109375, "Livedo reticularis": 6.388184635194754, "Loss of control of legs": 5.04898358831433, "Macule": 2.802642456092703, "Mass": 120.83878278883608, "Mental impairment": 24.285711687637445, "Mental status changes": 30.643123341667888, "Mobility decreased": 28.04932357926465, "Motor dysfunction": 8.128637198305313, "Movement disorder": 16.99093514477029, "Muscle atrophy": 2.7015857282212723, "Muscle contractions involuntary": 2.1274734560659434, "Muscle contracture": 57.46387176007076, "Muscle fatigue": 3.4142423782617337, "Muscle fibrosis": 190.51015348922263, "Muscle spasms": 7.797043518152326, "Muscle tightness": 14.429060955606436, "Muscular weakness": 4.3130281200882346, "Musculoskeletal disorder": 2.254141959187124, "Musculoskeletal stiffness": 6.461734883825051, "Myocardial fibrosis": 11.17510169807368, "Myosclerosis": 136.6886234996496, "Nephrogenic systemic fibrosis": 639.5132296893016, "Neuropathic arthropathy": 19.30969205579556, "Nodule": 2.628598509815405, "Ocular icterus": 8.606465085381101, "Oedema": 2.9731341476076505, "Oedema peripheral": 7.378913265138217, "Onychomadesis": 3.5367906725961964, "Osteomyelitis": 3.578151098040038, "Pain": 4.629508038380628, "Pain of skin": 8.871497740241914, "Papule": 3.125187504547718, "Paraesthesia": 4.2940735796421095, "Peau d'orange": 1367.7014714439697, "Peripheral ischaemia": 3.960055522563656, "Peroneal nerve palsy": 3.9354419225954103, "Pigmentation disorder": 8.106690691395034, "Plantar fasciitis": 5.216795573526623, "Post inflammatory pigmentation change": 43.121424622012185, "Product prescribing error": 2.0259540127447817, "Quality of life decreased": 10.337816255591784, "Rash": 2.281170850558884, "Rash macular": 3.5487802114495945, "Rash papular": 4.797742452192033, "Scab": 3.6511365626289, "Scar": 103.21371493084332, "Sclerodactylia": 243.49001473448632, "Scleroderma": 9.518087790306872, "Skin abrasion": 6.947744541526506, "Skin atrophy": 22.917234094784803, "Skin burning sensation": 4.085533061709405, "Skin discolouration": 19.06909304230157, "Skin disorder": 10.175293435584846, "Skin exfoliation": 7.965240173412081, "Skin fibrosis": 1003.5737319449272, "Skin fissures": 10.138605314112649, "Skin hyperpigmentation": 98.62015591298464, "Skin hypertrophy": 432.90689983110553, "Skin hypopigmentation": 38.29635548342187, "Skin induration": 465.0880855715105, "Skin lesion": 11.374394007831654, "Skin mass": 15.225302075083167, "Skin necrosis": 4.203269806868773, "Skin oedema": 6.21524085008329, "Skin plaque": 41.0394106745083, "Skin swelling": 30.4873981787522, "Skin tightness": 376.5401583305209, "Skin ulcer": 9.160464757448402, "Skin warm": 2.7263703657254266, "Skin wrinkling": 12.567536580225786, "Soft tissue disorder": 19.112653642371285, "Staphylococcal sepsis": 2.573547081837788, "Stasis dermatitis": 27.675873345745696, "Tendon disorder": 3.5843842753130137, "Ulcer": 2.368667764915237, "Wheelchair user": 9.718743097686168, "Xerosis": 27.82084979076061}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/827.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/827.json
index 3eece064892..734b23b08bc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/827.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/827.json
@@ -1 +1 @@
-{"Diarrhoea ": 2.9770304467694824, "Drug hypersensitivity ": 4.151935281439509, "Psoriasis ": 38.38255102083125, "Psoriatic arthropathy ": 26.592657008632838, "Weight decreased ": 4.909919295936933}
\ No newline at end of file
+{"Diabetes mellitus inadequate control": 140.78213247575314, "Glycosylated haemoglobin increased": 126.52260579786405}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/828.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/828.json
index f746bbfa5c9..460af321c87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/828.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/828.json
@@ -1 +1 @@
-{"Blood pressure increased ": 3.1218108046572746, "Drug abuse ": 7.128216886330796, "Insomnia ": 2.366340398865943, "Intentional product misuse ": 7.512509041822097, "Substance abuse ": 37.17149324059408, "Suicide attempt ": 7.229269849543266}
\ No newline at end of file
+{"Drug interaction": 13.433001069674203}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/829.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/829.json
index cc54aeb3ef8..00e573ca2e0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/829.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/829.json
@@ -1 +1 @@
-{"Ovarian hyperstimulation syndrome ": 1564.2258460080902}
\ No newline at end of file
+{"Arthritis": 3.425918491940197, "Arthropathy": 2.3190781281418658, "Back pain": 2.3974858002712147, "Blood pressure systolic increased": 14.795038480220551, "Bronchitis": 6.5106885520573154, "Bursitis": 12.152543009605704, "Cellulitis": 5.029757500939479, "Coeliac disease": 19.83955602045032, "Constipation": 2.338256310991216, "Contraindicated product administered": 3.83833386111682, "Cystitis": 7.157876606904978, "Drug hypersensitivity": 8.3542726800831, "Drug ineffective": 2.7339566977541723, "Fine motor skill dysfunction": 59.34257728786208, "Fluid retention": 21.03764215368201, "Food allergy": 59.5944235503269, "Gait disturbance": 3.1882487829408226, "Gastric ulcer": 11.267038271481676, "Heart rate decreased": 7.600888751752111, "Hepatic enzyme increased": 7.144260397548922, "Hyperhidrosis": 2.0502359543321966, "Hypersensitivity": 2.999620539172354, "Immunodeficiency": 40.98806332739078, "Infusion related reaction": 5.132780364916249, "Injection site induration": 10.42593001277369, "Instillation site inflammation": 5460.864244745746, "Intervertebral disc protrusion": 16.170544142926982, "Joint dislocation": 24.99637547874075, "Joint effusion": 35.47490257158812, "Joint swelling": 2.8939897817110403, "Lethargy": 2.4815247355441588, "Memory impairment": 2.074280176173975, "Nasopharyngitis": 2.1577572809186254, "Osteoarthritis": 10.960790873486228, "Product use issue": 2.7706100337325945, "Rash erythematous": 6.46270105032878, "Rheumatoid arthritis": 10.99652474063949, "Temperature regulation disorder": 53.367712192936494, "Treatment failure": 6.565342478946956, "Upper respiratory tract infection": 21.423602661702752, "Urinary retention": 2.2216236193284256, "Urinary tract infection": 2.665808221053456, "Vascular pain": 54.24031379539088, "Viral infection": 10.3124694356457, "Vitamin C decreased": 2757.3964565651327, "Vitamin D decreased": 49.59384394284945}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/83.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/83.json
index 780a780b1fe..8764a24ef4b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/83.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/83.json
@@ -1 +1 @@
-{"Pruritus ": 27.77970820789924, "Rash ": 21.00269848737633}
\ No newline at end of file
+{"Toxicity to various agents": 87.93454386707116}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/830.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/830.json
index 27f31dd8d13..49b47e4fa11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/830.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/830.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.522187518918283, "Abdominal distension ": 7.14126767522207, "Abdominal pain ": 5.493954304155022, "Abdominal pain lower ": 28.95095897584982, "Abortion spontaneous ": 9.620444076127043, "Adnexa uteri pain ": 51.017414811595714, "Adnexal torsion ": 591.9121127087847, "Ascites ": 133.2724701498231, "Breast pain ": 20.400663249231133, "Incorrect dose administered ": 4.398355316929645, "Oliguria ": 30.542230143812077, "Ovarian hyperstimulation syndrome ": 1323.0010622929744, "Pleural effusion ": 12.057259500379256, "Vaginal discharge ": 21.034741252317108}
\ No newline at end of file
+{"Abdominal discomfort": 3.942073738760807, "Abdominal distension": 10.029114237798856, "Abdominal pain": 4.732635404329264, "Abdominal pain lower": 23.462033419613583, "Abortion spontaneous": 23.42208079717694, "Ascites": 102.59086172730392, "Haematocrit increased": 161.93228765978904, "Incorrect route of product administration": 21.48588750191, "Ovarian hyperstimulation syndrome": 2249.0641223469383, "Overdose": 5.858271996896808, "Pelvic fluid collection": 925.225940880982, "Pleural effusion": 9.86960496566202}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/831.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/831.json
index e0e40e1d8e3..55cb57b0d51 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/831.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/831.json
@@ -1 +1 @@
-{"Sickle cell anaemia with crisis ": 1255.2332632313437}
\ No newline at end of file
+{"Asthenia": 4.496769090737259, "Hot flush": 32.71852701561732}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/832.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/832.json
index 3792d03c899..d8deec9cc60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/832.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/832.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.377770569090449, "Abnormal behaviour ": 3.974543768811076, "Accidental overdose ": 7.830287933504132, "Adverse drug reaction ": 2.7218198777741502, "Agitation ": 2.423883306611167, "Amnesia ": 3.848524935106429, "Anticholinergic syndrome ": 54.25472618169631, "Bladder spasm ": 102.10703220327738, "Choking ": 4.180684478378654, "Completed suicide ": 11.62991809039005, "Confusional state ": 4.90426215409359, "Constipation ": 4.783613167687282, "Cystitis ": 4.537729432017505, "Decubitus ulcer ": 15.403207351665197, "Dehydration ": 2.516671048046541, "Delirium ": 4.858517220410068, "Dementia ": 4.540028859091814, "Disorientation ": 2.5741361729414067, "Dizziness postural ": 3.83776226896576, "Drug abuse ": 2.3103916557890805, "Drug hypersensitivity ": 2.0179228833259284, "Drug level increased ": 3.111590089963627, "Drug withdrawal syndrome ": 2.716469793406256, "Dry eye ": 5.631148755555689, "Dry mouth ": 13.988663184173207, "Dry skin ": 2.4386337866298984, "Dysarthria ": 2.1413836295883426, "Dysphagia ": 2.2418088049038927, "Dysuria ": 4.433828689259756, "Encephalopathy ": 3.173506669922768, "Eructation ": 8.387980509593854, "Extrasystoles ": 4.195771481550629, "Fall ": 3.1214151075552232, "Flatulence ": 6.802921438206613, "Flushing ": 2.6806950944321217, "Gastrooesophageal reflux disease ": 4.8343267963461125, "Generalised tonic-clonic seizure ": 4.248019653007331, "Hallucination ": 5.711367998435299, "Hallucination, visual ": 2.3935303441415026, "Hallucinations, mixed ": 16.87351985190282, "Hypertonic bladder ": 38.76044063080097, "Incontinence ": 12.2114186684251, "Intentional overdose ": 2.7752177972143093, "Intentional self-injury ": 3.4815148195146457, "Lip swelling ": 2.8199647726728, "Medication error ": 2.1136027777281887, "Megacolon ": 46.68457477866456, "Mental status changes ": 5.412152830409378, "Micturition urgency ": 13.688573523647792, "Muscle spasticity ": 22.681988329537877, "Muscle tightness ": 4.936565431236237, "Musculoskeletal chest pain ": 13.129472780261862, "Musculoskeletal discomfort ": 4.386520725029194, "Nervous system disorder ": 5.71662493253048, "Nocturia ": 15.065990453928755, "Panic attack ": 2.183191114284211, "Pneumonia aspiration ": 4.669580535883602, "Pollakiuria ": 4.921441762447618, "Premature labour ": 10.622350016349966, "Psychotic disorder ": 4.930518849582636, "Respiratory arrest ": 4.455577458540758, "Restless legs syndrome ": 5.103425248562036, "Sedation ": 4.30290665048088, "Suspected suicide ": 15.88358502910902, "Swollen tongue ": 2.2422094983519347, "Toxicity to various agents ": 4.518411269372976, "Urinary incontinence ": 7.888278650636662, "Urinary retention ": 22.1011199461109, "Urinary tract infection ": 3.1917287338426426, "Urosepsis ": 10.918789326749826, "Vision blurred ": 3.2258182651922938, "Withdrawal syndrome ": 2.3781146169863603}
\ No newline at end of file
+{"Alanine aminotransferase increased": 4.888808557175275, "Aspartate aminotransferase increased": 5.5892127013615776, "Bacterial infection": 4.663154745259368, "Blood creatine phosphokinase increased": 5.952503525734808, "Bronchiectasis": 13.967229476221178, "Bronchopulmonary aspergillosis allergic": 84.25134927806295, "Bronchospasm": 5.628203537675902, "Chest discomfort": 4.254148501103174, "Cough": 2.8880481001409968, "Cystic fibrosis": 856.1778460442332, "Cystic fibrosis lung": 1762.147212870255, "Cystic fibrosis respiratory infection suppression": 4273.055114918833, "Distal intestinal obstruction syndrome": 172.42963801666235, "Dyspnoea": 2.0355758727005964, "Emotional disorder": 5.099836298815795, "Failure to thrive": 14.970730733254054, "Forced expiratory volume decreased": 210.98520079574155, "Haemoptysis": 13.127019942616585, "Hepatic cytolysis": 3.0588832808065307, "Hepatic enzyme increased": 2.7717948960003884, "Hospitalisation": 40.20109797178514, "Illness": 3.112634432889556, "Increased bronchial secretion": 40.84965511716271, "Infection": 13.5450673932968, "Infective pulmonary exacerbation of cystic fibrosis": 2780.692803587542, "Influenza": 4.422379182610666, "Intestinal obstruction": 12.892589610542563, "Liver function test increased": 4.7155056174303445, "Lower respiratory tract infection": 2.3053675980509354, "Lung disorder": 5.239077716003076, "Lung transplant": 112.21702162275216, "Mood swings": 3.379896707076513, "Nasal congestion": 2.2737378618230006, "Nasopharyngitis": 2.893477273184738, "Pneumonia": 7.335855264313565, "Pneumonia pseudomonal": 37.72375508149661, "Pneumonia staphylococcal": 34.55838598085397, "Pneumothorax": 13.334877501826746, "Productive cough": 6.474440952637258, "Pseudomonas infection": 59.52932317879984, "Pulmonary function test decreased": 366.0563109608832, "Rales": 6.697439608737049, "Respiration abnormal": 45.7458022871807, "Respiratory disorder": 3.1851075493451675, "Respiratory failure": 3.85124361039721, "Respiratory symptom": 23.92436941742956, "Respiratory syncytial virus infection": 10.525695005938278, "Respiratory tract infection": 5.24819095864479, "Rhinovirus infection": 27.60171613281335, "Sinus disorder": 7.228140265439216, "Sinus operation": 148.9677654427281, "Sinusitis": 4.463458862366823, "Sputum increased": 47.25802614294438, "Staphylococcal infection": 12.543138387665088, "Stenotrophomonas infection": 40.120419749451166, "Surgery": 4.970935843249374, "Transaminases increased": 3.7716131152085945, "Treatment noncompliance": 10.250656578709323, "Upper limb fracture": 4.906698835782488, "Upper respiratory tract infection": 2.2518345110030458, "Viral infection": 9.85631440855826, "Weight decreased": 2.493544631029533, "Wheezing": 2.1138630971925827}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/833.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/833.json
index a2f7441f871..47ad5b2e6ce 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/833.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/833.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 3.226408112857848, "Abdominal distension ": 2.5039593129162188, "Atrial fibrillation ": 3.946347968443265, "Blood calcium decreased ": 19.014919689314556, "Blood glucose abnormal ": 10.328735218500436, "Blood glucose decreased ": 9.544324458130914, "Blood glucose increased ": 5.928885522999684, "Blood iron decreased ": 44.71847159120878, "Blood iron increased ": 177.15388007970424, "Blood potassium decreased ": 5.435116850613218, "Blood pressure decreased ": 2.0108451744287623, "Blood triglycerides increased ": 18.80834962081988, "Blood uric acid increased ": 20.203067981678025, "Bone marrow disorder ": 92.33942729317032, "Bone marrow failure ": 23.68087113031917, "Cholecystitis ": 11.39062469689137, "Cholelithiasis ": 5.811138751761907, "Chronic kidney disease ": 2.568537108882143, "Constipation ": 2.332732824308647, "Decreased appetite ": 2.7501084811527803, "Dehydration ": 7.3989230004802, "Depression ": 2.1263734495965623, "Disability ": 8.755747922266115, "Diverticulitis ": 13.97869306566334, "Dyspepsia ": 3.266155724098223, "Epistaxis ": 2.592447551719012, "Eructation ": 13.088507119337809, "Feeling abnormal ": 2.199208541136342, "Flatulence ": 5.956824684604923, "Fluid retention ": 3.3487453387948785, "Full blood count abnormal ": 9.595250146917904, "Gastrointestinal disorder ": 4.552604323420191, "Glycosylated haemoglobin increased ": 8.699675955955563, "Hepatic pain ": 55.69969086080869, "Hepatomegaly ": 24.46817337092776, "Hypermetropia ": 234.43314997616017, "Hypoglycaemia ": 2.4397341665644445, "Immune system disorder ": 22.509212023135564, "Impaired gastric emptying ": 24.96230459360585, "International normalised ratio decreased ": 19.860008161700613, "Intervertebral disc protrusion ": 16.132358276767903, "Lactic acidosis ": 4.055427963833002, "Memory impairment ": 5.183641924205403, "Meniscus injury ": 62.46572376117647, "Mental impairment ": 12.690196665574875, "Myopia ": 84.64024074534038, "Nasopharyngitis ": 2.006059205063244, "Nephrolithiasis ": 6.057813465282492, "Pancreatitis ": 4.855400812138701, "Pancreatitis acute ": 5.38146513186418, "Product availability issue ": 16.396631808839434, "Proteinuria ": 3.9843664915520103, "Red blood cell count decreased ": 7.238290842553463, "Renal disorder ": 4.571270239332722, "Retinopathy ": 25.79569981755616, "Road traffic accident ": 4.889178390555089, "Sinusitis ": 5.467803212446788, "Sneezing ": 11.60759525398657, "Splenomegaly ": 9.55335328112592, "Synovial cyst ": 37.67093384264987, "Tooth infection ": 34.463100316907365, "Vomiting ": 2.4038991708639057, "Weight decreased ": 4.9094592125900345}
\ No newline at end of file
+{"Abdominal pain": 3.500259164438527, "Drug interaction": 16.37897112555646, "Renal impairment": 15.060810848822332}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/834.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/834.json
index 078b3f5f208..51b73e663ba 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/834.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/834.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 4.770223754526268, "Acute promyelocytic leukaemia ": 34.86832352491992, "Agranulocytosis ": 5.400041867307678, "Alopecia ": 2.513743454030984, "Anaemia ": 2.978470831447173, "Ascites ": 2.0264143546980544, "Breast cancer ": 3.0103247338890853, "Breast cancer metastatic ": 4.32039000032839, "Breast cancer recurrent ": 20.96213965481388, "Cardiac dysfunction ": 42.873290971667046, "Cardiotoxicity ": 13.079300952149048, "Colitis ": 2.655044352214303, "Cytopenia ": 7.43640178720185, "Disease progression ": 6.247211328299993, "Disseminated intravascular coagulation ": 3.0054411477035305, "Drug-induced liver injury ": 4.177350083063442, "Ejection fraction decreased ": 12.104541462081706, "Febrile neutropenia ": 8.317356022640972, "Flushing ": 2.9985932135868434, "Gastrointestinal disorder ": 2.156574212832773, "General physical health deterioration ": 2.123779093164028, "Granulocyte count decreased ": 8.950975550845312, "Granulocytopenia ": 10.158033815969738, "Haematotoxicity ": 15.127491562013253, "Hepatic function abnormal ": 4.07166048630619, "Hypersensitivity pneumonitis ": 18.198247742025284, "Hypothyroidism ": 2.3342781242198027, "Hypoxia ": 2.2256927357535754, "Immune-mediated hepatitis ": 18.712096058685947, "Immune-mediated hypothyroidism ": 11.46201496584662, "Infusion related reaction ": 2.0721947443348614, "Interstitial lung disease ": 3.267595172648825, "Invasive ductal breast carcinoma ": 9.354798349180683, "Leukopenia ": 7.077457290827546, "Liver injury ": 3.0279507347302164, "Malignant neoplasm progression ": 9.224935846706318, "Metastases to bone ": 13.182002823954797, "Metastases to central nervous system ": 8.477027558357051, "Metastases to liver ": 8.32848896061637, "Metastases to lung ": 8.522404990230545, "Metastases to lymph nodes ": 13.60697261388922, "Mucosal inflammation ": 2.8878591677951824, "Myelosuppression ": 42.57353739824841, "Neoplasm progression ": 4.04961524736345, "Neuropathy peripheral ": 6.591801726651871, "Neurotoxicity ": 4.980259111635566, "Neutropenia ": 7.150635330859115, "Neutrophil count decreased ": 22.89454791394576, "Non-small cell lung cancer ": 10.997894707503384, "Pancytopenia ": 3.6361545709060583, "Pericardial effusion ": 2.0323053314220214, "Peripheral sensory neuropathy ": 12.865449832205602, "Platelet count decreased ": 3.52739224219964, "Pleural effusion ": 2.119235437801376, "Pneumonitis ": 6.586848759406368, "Polyneuropathy ": 4.577187379605625, "Premature baby ": 2.2583734658357515, "Product use in unapproved indication ": 2.505302892729917, "Second primary malignancy ": 6.264088195099037, "Septic shock ": 2.573697234036233, "Therapy partial responder ": 17.959005945723682, "Thrombocytopenia ": 2.061608055933207, "Thyroiditis ": 7.414635514765443, "Transaminases increased ": 3.364711090875637, "White blood cell count decreased ": 16.075427350488546}
\ No newline at end of file
+{"Condition aggravated": 2.681991856107963, "Drug ineffective": 3.3901631803678227, "Drug interaction": 3.3406336642954604, "Drug resistance": 10.3997089083515, "Drug-induced liver injury": 5.06535907007394, "Electrocardiogram QT prolonged": 3.324427897010496, "Enterocolitis haemorrhagic": 68.26254035280253, "Erythema multiforme": 6.166523403500603, "Exposure during pregnancy": 3.010433366954093, "Foetal death": 14.3726956600107, "Foetal exposure during pregnancy": 14.20124506709699, "Foetal growth restriction": 29.65656131696017, "Hallucination": 4.045122864211468, "Hypoxia": 8.192240618259053, "International normalised ratio increased": 11.203657936697203, "Low birth weight baby": 19.508678938503497, "Maternal exposure during pregnancy": 11.32997835754546, "Pathogen resistance": 108.42485152512316, "Premature baby": 10.947227006336307, "Premature delivery": 42.38847643028049, "Rash": 2.383978576201684, "Rash maculo-papular": 2.6586810172186124, "Respiratory distress": 5.061032356298201, "Respiratory failure": 4.056413338837996, "Rhabdomyolysis": 2.967152912319696, "Stevens-Johnson syndrome": 4.290335738141466, "Stillbirth": 70.6872639638126, "Swelling face": 2.0656423248005717, "Toxic epidermal necrolysis": 7.349449915721306}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/835.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/835.json
index d9c94c8db4e..62736ae5a48 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/835.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/835.json
@@ -1 +1 @@
-{"Neuropathy peripheral ": 17.53286875165086, "Off label use ": 3.681741211799794, "Product use issue ": 17.66970884703083, "Rash ": 3.71706547351106}
\ No newline at end of file
+{"Acquired gene mutation": 1267.3087728740286, "Cardiac failure": 4.929422445939224, "Cardiomyopathy": 6.939818742311763, "Cardiotoxicity": 26.771586678691445, "Deep vein thrombosis": 3.057609333367075, "Disease progression": 5.982463005698374, "Drug resistance": 104.07428461205674, "EGFR gene mutation": 812.9786154550924, "Electrocardiogram QT prolonged": 5.64770763476954, "Interstitial lung disease": 16.746301250464988, "Malignant neoplasm progression": 46.0742427092143, "Malignant transformation": 887.0728703677532, "Metastases to bone": 19.71399934239578, "Metastases to central nervous system": 67.20668007534422, "Metastases to liver": 20.23584385119665, "Metastases to lung": 20.150139670735104, "Metastases to lymph nodes": 19.914064423452132, "Metastases to meninges": 313.46420020359267, "Metastasis": 21.220950133878887, "Mucosal inflammation": 9.77079322761784, "Myelosuppression": 3.9137885572720768, "Off label use": 2.227508363142809, "Paronychia": 101.30965749809664, "Platelet count decreased": 2.479700193737973, "Pleural effusion": 6.853356246403804, "Pneumonitis": 53.44695903828789, "Pulmonary embolism": 4.272548256537188, "Respiratory failure": 4.806146009318086, "Skin toxicity": 23.382472701422863, "Thrombocytopenia": 4.565068011517947, "Torsade de pointes": 9.240178552416998}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/836.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/836.json
index cb91cc33a51..b7f512a77e3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/836.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/836.json
@@ -1 +1 @@
-{"Joint injury ": 330.36144888742234, "Musculoskeletal pain ": 135.39174423901332}
\ No newline at end of file
+{"Drug reaction with eosinophilia and systemic symptoms": 36.9002321363029, "Pruritus": 2.7061196570420107}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/837.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/837.json
index 1f3edf862f8..63a85957cea 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/837.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/837.json
@@ -1 +1 @@
-{"Febrile neutropenia ": 7.63696506270799, "Haemoglobin decreased ": 5.9023788002993145, "Malignant neoplasm progression ": 4.67972848222079, "Neoplasm progression ": 32.93367121164228, "Neutropenia ": 16.458955226985417, "Neutrophil count decreased ": 10.698972995350609}
\ No newline at end of file
+{"Diarrhoea": 2.977005601932708, "Drug hypersensitivity": 4.151935281439509, "Psoriasis": 38.38255102083125, "Psoriatic arthropathy": 26.592657008632838, "Weight decreased": 4.909919295936933}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/838.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/838.json
index b1b67c5bd4d..9e61edefbdd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/838.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/838.json
@@ -1 +1 @@
-{"Agitation ": 4.417861392365098, "Alanine aminotransferase increased ": 3.1201835625851184, "Altered state of consciousness ": 5.854295983308866, "Anxiety ": 2.349022033762413, "Aspartate aminotransferase increased ": 3.1496770467135624, "Blood creatine phosphokinase increased ": 5.758346355844452, "Cardiac arrest ": 3.400350905701708, "Completed suicide ": 6.398956770838945, "Confusional state ": 2.0147222200434007, "Constipation ": 2.946819102052445, "Delusion ": 20.998724996593538, "Depression ": 3.146461521521919, "Drug abuse ": 3.801343130606583, "Drug interaction ": 5.884099235935408, "Extrapyramidal disorder ": 34.98160331614806, "Hallucination ": 4.432568208933654, "Intentional product misuse ": 3.538349011329053, "Mental status changes ": 14.321456635387635, "Muscle rigidity ": 33.29453172440556, "Myocarditis ": 6.188728971692331, "Neuroleptic malignant syndrome ": 45.18296401804053, "Platelet count decreased ": 2.02110970608891, "Schizophrenia ": 30.07224782992016, "Sinus tachycardia ": 17.46551794281048, "Toxicity to various agents ": 8.912159776758319, "Troponin increased ": 33.06369737596907}
\ No newline at end of file
+{"Blood pressure increased": 3.1217560198219694, "Drug abuse": 7.128216886330796, "Insomnia": 2.366340398865943, "Intentional product misuse": 7.512509041822097, "Substance abuse": 37.17149324059408, "Suicide attempt": 7.229269849543266}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/839.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/839.json
index ad7eeb8880c..d17a3fbfcaa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/839.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/839.json
@@ -1 +1 @@
-{"Myelosuppression ": 25.27011654010468}
\ No newline at end of file
+{"Ovarian hyperstimulation syndrome": 1564.2258460080902}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/84.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/84.json
index d887e636f89..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/84.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/84.json
@@ -1 +1 @@
-{"Foetal exposure during pregnancy ": 6.945300574762279}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/840.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/840.json
index 9e26dfeeb6e..4a92ccd5fb5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/840.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/840.json
@@ -1 +1 @@
-{}
\ No newline at end of file
+{"Abdominal discomfort": 2.522187518918283, "Abdominal distension": 7.14126767522207, "Abdominal pain": 5.493954304155022, "Abdominal pain lower": 28.95095897584982, "Abortion spontaneous": 9.620444076127043, "Adnexa uteri pain": 51.017414811595714, "Adnexal torsion": 591.9121127087847, "Ascites": 133.2724701498231, "Breast pain": 20.400663249231133, "Incorrect dose administered": 4.398355316929645, "Oliguria": 30.542230143812077, "Ovarian hyperstimulation syndrome": 1323.0010622929744, "Pleural effusion": 12.056148657861902, "Vaginal discharge": 21.034741252317108}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/841.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/841.json
index 54f983d8857..8f86996cb03 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/841.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/841.json
@@ -1 +1 @@
-{"Carcinoembryonic antigen increased ": 71.55271718577454, "Colorectal cancer metastatic ": 179.06056635253694, "Conjunctivitis ": 14.84816037599784, "Constipation ": 3.746494245105028, "Decreased appetite ": 2.0507185418991187, "Dehydration ": 2.319805337464837, "Dermatitis acneiform ": 252.1960532479539, "Diarrhoea ": 2.895725298359987, "Disease progression ": 2.6827067926305115, "Drug resistance ": 5.462208552802176, "Febrile neutropenia ": 10.10843594832608, "Hepatic encephalopathy ": 23.76121476728033, "Hyperammonaemia ": 27.327104888389982, "Hypomagnesaemia ": 104.78900949670944, "Interstitial lung disease ": 8.23785319977784, "Leukopenia ": 2.493709518175643, "Metastases to liver ": 18.687314237067422, "Myelosuppression ": 4.677550248368575, "Neuropathy peripheral ": 18.821014919104133, "Neurotoxicity ": 29.940356339272107, "Neutropenia ": 11.851961271274202, "Neutrophil count decreased ": 4.382190066521645, "Palmar-plantar erythrodysaesthesia syndrome ": 5.486448857272092, "Paraesthesia ": 2.317240975091024, "Paronychia ": 236.9122316971992, "Peripheral sensory neuropathy ": 38.809223758920666, "Pneumonia aspiration ": 9.305473080743532, "Polyneuropathy ": 17.62130888824201, "Rash ": 3.5228901889837947, "Rash maculo-papular ": 3.111255042219162, "Rash pustular ": 38.03705630434703, "Renal tubular disorder ": 35.64491850837888, "Skin disorder ": 12.844063465430075, "Skin toxicity ": 211.77842395279416, "Stomatitis ": 14.775462739678083, "Therapeutic product effect incomplete ": 2.1212230937447853, "Therapy partial responder ": 74.4823847479434, "Thrombocytopenia ": 6.577652329002839, "Venoocclusive liver disease ": 27.736317591500065}
\ No newline at end of file
+{"Sickle cell anaemia with crisis": 1255.2332632313437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/842.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/842.json
index 80c8414a9ae..d594eb4d262 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/842.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/842.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.0025006641349647, "Acute generalised exanthematous pustulosis ": 5.211711439464579, "Acute hepatic failure ": 2.568373389376927, "Acute kidney injury ": 2.288960837286181, "Agranulocytosis ": 2.912063221209612, "Alkalosis hypochloraemic ": 101.91377913855784, "Allergy to animal ": 47.73836835976505, "Antineutrophil cytoplasmic antibody positive ": 51.87459937090336, "Appetite disorder ": 3.460504311852878, "Asthma ": 2.3572900076589955, "Ataxia ": 5.778703416993072, "Atelectasis ": 8.742439929774813, "Atrial fibrillation ": 2.045341204475924, "Atrial flutter ": 2.286983998935986, "Bladder transitional cell carcinoma ": 44.18745718390277, "Blood magnesium decreased ": 15.218748543545493, "Blood phosphorus decreased ": 14.019854811125455, "Blood potassium decreased ": 2.955336065273546, "Blood pressure diastolic decreased ": 30.956320520812373, "Blood pressure systolic decreased ": 9.16132134477122, "Blood pressure systolic increased ": 14.128350794261628, "Blood triglycerides increased ": 3.869062506021319, "Blood urea increased ": 3.181715967550581, "Body temperature decreased ": 20.32743252237411, "Breath sounds abnormal ": 8.986749377137475, "Bronchial disorder ": 47.23891419686456, "Bronchial obstruction ": 27.16930056752932, "Bronchiectasis ": 2.5151533880274, "Bronchitis ": 3.1280184967955167, "Carcinoid tumour ": 111.28891444343508, "Cardiac failure chronic ": 8.36695659827363, "Cardiac murmur ": 2.361995770392136, "Choking ": 2.005047878103515, "Cholelithiasis ": 2.0393527855039646, "Cholestasis ": 6.456960811393289, "Chronic obstructive pulmonary disease ": 3.0829464379528, "Completed suicide ": 5.556029366366125, "Coronary artery bypass ": 7.934871352749409, "Creatinine renal clearance decreased ": 3.623678752599519, "Crohn's disease ": 2.275134595879334, "Decreased immune responsiveness ": 9.80154880107053, "Dehydration ": 2.6206706042209182, "Dilated cardiomyopathy ": 3.266267189842353, "Disease recurrence ": 5.858746857061088, "Diverticulum intestinal ": 3.407102626698349, "Drug interaction ": 2.6994336712150377, "Drug reaction with eosinophilia and systemic symptoms ": 6.759418479390445, "Duodenal ulcer ": 3.553693230843065, "Dust allergy ": 25.50882618684002, "Dyspnoea at rest ": 7.485024691876232, "Dyspnoea exertional ": 3.900207705920399, "Ecchymosis ": 3.4578867794288284, "Ejection fraction decreased ": 3.985439746696489, "Electrolyte imbalance ": 5.11357497549414, "End stage renal disease ": 3.826238388599465, "Eosinophilia ": 7.126923951347549, "Erythema nodosum ": 11.068155288946382, "Exercise tolerance decreased ": 5.143940418699156, "Eye pruritus ": 3.074106916928772, "Fall ": 2.0958945562881843, "Fixed eruption ": 6.132837367667432, "Frequent bowel movements ": 3.66422873196264, "Full blood count abnormal ": 6.221342804685814, "Gastric haemorrhage ": 2.038616831747365, "Gastritis ": 2.536647848078964, "Gastritis fungal ": 611.4482253764104, "Gastrointestinal obstruction ": 16.61317386606097, "Grandiosity ": 56.5453531010181, "Grip strength decreased ": 4.580796621850888, "Heart rate decreased ": 4.518689831524696, "Hepatic cytolysis ": 6.173434281908447, "Hepatic pain ": 3.810240650192357, "Hepatic steatosis ": 2.08926869072572, "Hepatitis A antibody abnormal ": 1130.341188694426, "Hepatitis cholestatic ": 8.286009017230423, "Hepatomegaly ": 2.6609816737329206, "Hip fracture ": 4.70474611388028, "Hypercalcaemia ": 3.4644149399409105, "Hypercholesterolaemia ": 2.142046353793268, "Hyperkalaemia ": 2.0032822689240697, "Hypernatraemia ": 6.213643666350265, "Hypocalcaemia ": 7.256601334272997, "Hypokalaemia ": 2.0284315296010758, "Hypomagnesaemia ": 18.934579906530296, "Hyponatraemia ": 5.084263988126934, "Hypopnoea ": 7.827678239651715, "Immune thrombocytopenia ": 2.2253361484162384, "Implant site dehiscence ": 213.77349202416715, "Implant site erosion ": 101.5500062207642, "Implant site erythema ": 112.87100087956834, "Implant site inflammation ": 203.80122711198308, "Implant site pruritus ": 453.741438065735, "Inappropriate antidiuretic hormone secretion ": 3.623630397504133, "Klebsiella test positive ": 112.63064890491444, "Lacrimation increased ": 2.0005300337806, "Lactic acidosis ": 2.646179865189945, "Large intestine polyp ": 12.965964232092604, "Libido increased ": 8.035659682944493, "Loss of personal independence in daily activities ": 3.928475453990444, "Low birth weight baby ": 2.836875361485474, "Lung consolidation ": 8.576661420585728, "Lung disorder ": 2.055998363455411, "Lung opacity ": 8.60266563296315, "Lymphopenia ": 2.17658035063958, "Medical device site bruise ": 512.8726411463114, "Medical device site erosion ": 120.44037892017955, "Medical device site erythema ": 147.20905208316307, "Medical device site haemorrhage ": 157.729003413971, "Mental disorder ": 7.765789611244798, "Mental impairment ": 2.60990286126989, "Mitral valve incompetence ": 3.5131424198356003, "Mood altered ": 2.5556111218383437, "Muscle atrophy ": 2.11025283295399, "Nasal polyps ": 15.022383563728509, "Needle issue ": 6.658691855814617, "Obstructive airways disorder ": 6.994172432874352, "Oesophagitis ": 2.9722990858142424, "Oral mucosal eruption ": 7.882798355272097, "Oropharyngeal discomfort ": 3.135450896599251, "Osteoarthritis ": 2.063673387923775, "Papillary renal cell carcinoma ": 170.29637498110682, "Parkinson's disease ": 4.848278624168591, "Persecutory delusion ": 12.139531286875318, "Petechiae ": 2.1824334867224597, "Platelet count increased ": 3.0373225541014124, "Pleuritic pain ": 13.008268417714902, "Poisoning ": 2.670251031494801, "Pregnancy ": 2.241306864260675, "Premature labour ": 8.194132050849895, "Productive cough ": 4.8275802264505145, "Pseudomembranous colitis ": 7.692721310931113, "Psychiatric symptom ": 3.35382497446061, "Pulmonary congestion ": 2.6408026265386635, "Rash maculo-papular ": 6.852038565926217, "Rash pustular ": 4.145341114980701, "Rebound acid hypersecretion ": 201.99861287978104, "Seasonal allergy ": 6.329050494785357, "Shock haemorrhagic ": 2.5752072038580494, "Sleep disorder due to a general medical condition ": 9.535732436272411, "Spinal stenosis ": 6.454710541672579, "Suspected suicide ": 13.106112024400746, "Symmetrical drug-related intertriginous and flexural exanthema ": 36.53741958684044, "Therapeutic product effect incomplete ": 3.319942534893044, "Therapy cessation ": 4.831832781075586, "Therapy interrupted ": 5.390020646762437, "Tonsil cancer ": 40.74595820885498, "Toxic epidermal necrolysis ": 6.325751750610192, "Toxic skin eruption ": 2.0691621885211884, "Tricuspid valve incompetence ": 4.351704328288826, "Troponin increased ": 4.382389157100061, "Tubulointerstitial nephritis ": 8.869809462172421, "Urinary incontinence ": 3.3485943975497943, "Ventricular hypertrophy ": 38.86235888093664, "Ventricular hypokinesia ": 18.019966680824023, "Vitamin B12 decreased ": 36.46712627755692, "Vitamin B12 deficiency ": 14.746295557780602, "Wheelchair user ": 7.979754646464273, "Wheezing ": 5.52654720712097}
\ No newline at end of file
+{"Abdominal distension": 2.377770569090449, "Abnormal behaviour": 3.974543768811076, "Accidental overdose": 7.830287933504132, "Adverse drug reaction": 2.7218198777741502, "Agitation": 2.423883306611167, "Amnesia": 3.848524935106429, "Anticholinergic syndrome": 54.25472618169631, "Bladder spasm": 102.10703220327738, "Choking": 4.180684478378654, "Completed suicide": 11.62991809039005, "Confusional state": 4.90426215409359, "Constipation": 4.783613167687282, "Cystitis": 4.537729432017505, "Decubitus ulcer": 15.403207351665197, "Dehydration": 2.5165366660143964, "Delirium": 4.858517220410068, "Dementia": 4.540028859091814, "Disorientation": 2.5741361729414067, "Dizziness postural": 3.83776226896576, "Drug abuse": 2.3103916557890805, "Drug hypersensitivity": 2.0179228833259284, "Drug level increased": 3.111590089963627, "Drug withdrawal syndrome": 2.716469793406256, "Dry eye": 5.631148755555689, "Dry mouth": 13.988663184173207, "Dry skin": 2.4386337866298984, "Dysarthria": 2.1413836295883426, "Dysphagia": 2.2418088049038927, "Dysuria": 4.433828689259756, "Encephalopathy": 3.173506669922768, "Eructation": 8.387980509593854, "Extrasystoles": 4.195771481550629, "Fall": 3.121335043869307, "Flatulence": 6.802367778743, "Flushing": 2.6806950944321217, "Gastrooesophageal reflux disease": 4.8343267963461125, "Generalised tonic-clonic seizure": 4.248019653007331, "Hallucination": 5.711367998435299, "Hallucination, visual": 2.3935303441415026, "Hallucinations, mixed": 16.87351985190282, "Hypertonic bladder": 38.76044063080097, "Incontinence": 12.2114186684251, "Intentional overdose": 2.7752177972143093, "Intentional self-injury": 3.4815148195146457, "Lip swelling": 2.819790701261078, "Medication error": 2.1134511171033488, "Megacolon": 46.68457477866456, "Mental status changes": 5.412152830409378, "Micturition urgency": 13.688573523647792, "Muscle spasticity": 22.676085063485704, "Muscle tightness": 4.936565431236237, "Musculoskeletal chest pain": 13.129472780261862, "Musculoskeletal discomfort": 4.386520725029194, "Nervous system disorder": 5.71662493253048, "Nocturia": 15.065990453928755, "Panic attack": 2.183191114284211, "Pneumonia aspiration": 4.669580535883602, "Pollakiuria": 4.921441762447618, "Premature labour": 10.622350016349966, "Psychotic disorder": 4.930518849582636, "Respiratory arrest": 4.455577458540758, "Restless legs syndrome": 5.103425248562036, "Sedation": 4.30290665048088, "Suspected suicide": 15.88358502910902, "Swollen tongue": 2.2422094983519347, "Toxicity to various agents": 4.518411269372976, "Urinary incontinence": 7.888278650636662, "Urinary retention": 22.1011199461109, "Urinary tract infection": 3.1917287338426426, "Urosepsis": 10.918789326749826, "Vision blurred": 3.2258182651922938, "Withdrawal syndrome": 2.3781146169863603}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/843.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/843.json
index e3594f5ffb0..7fb303159f5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/843.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/843.json
@@ -1 +1 @@
-{"Anaphylactic reaction ": 46.2812076369364}
\ No newline at end of file
+{"Abdominal discomfort": 3.22450344779733, "Abdominal distension": 2.502481886377928, "Atrial fibrillation": 3.943910916622019, "Blood calcium decreased": 19.00370063589676, "Blood glucose abnormal": 10.32264089727398, "Blood glucose decreased": 9.538690544824007, "Blood glucose increased": 5.925383297045361, "Blood iron decreased": 44.69208175911565, "Blood iron increased": 177.04934095640448, "Blood potassium decreased": 5.431910715250264, "Blood pressure decreased": 2.009593570135137, "Blood triglycerides increased": 18.797250515978536, "Blood uric acid increased": 20.191147906856116, "Bone marrow disorder": 92.2849368693547, "Bone marrow failure": 23.666896682547037, "Cholecystitis": 11.383905455905134, "Cholelithiasis": 5.807710504197421, "Chronic kidney disease": 2.5668716289223195, "Constipation": 2.331356027106043, "Decreased appetite": 2.748457694280259, "Dehydration": 7.394158523927566, "Depression": 2.1251183405781395, "Disability": 8.75058274214842, "Diverticulitis": 13.970443235637882, "Dyspepsia": 3.2642283098720006, "Epistaxis": 2.590917654889746, "Eructation": 13.080785637197332, "Feeling abnormal": 2.197868318954339, "Flatulence": 5.952825853691669, "Fluid retention": 3.346769938136981, "Full blood count abnormal": 9.589587649052197, "Gastrointestinal disorder": 4.549773796014306, "Glycosylated haemoglobin increased": 8.694542836589525, "Hepatic pain": 55.66682175376164, "Hepatomegaly": 24.45373386216384, "Hypermetropia": 234.29481117765732, "Hypoglycaemia": 2.4382117764287923, "Immune system disorder": 22.49592856114517, "Impaired gastric emptying": 24.94757765689803, "International normalised ratio decreased": 19.848292908496667, "Intervertebral disc protrusion": 16.122839969193087, "Lactic acidosis": 4.053035294571535, "Memory impairment": 5.180581912846876, "Meniscus injury": 62.42886835829968, "Mental impairment": 12.682707973481596, "Myopia": 84.59029363798813, "Nasopharyngitis": 2.0047227552106133, "Nephrolithiasis": 6.053237934785472, "Pancreatitis": 4.852534953671722, "Pancreatitis acute": 5.378289760485154, "Product availability issue": 16.386957945067024, "Proteinuria": 3.982016142742893, "Red blood cell count decreased": 7.234020149227523, "Renal disorder": 4.567899181604127, "Retinopathy": 25.780481206663197, "Road traffic accident": 4.886294171118387, "Sinusitis": 5.464576569426344, "Sneezing": 11.600746116193337, "Splenomegaly": 9.547717579150437, "Synovial cyst": 37.64871211772977, "Tooth infection": 34.44276667212957, "Vomiting": 2.402446119182058, "Weight decreased": 4.906559221611873}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/844.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/844.json
index 99808ef2113..eff32c245bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/844.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/844.json
@@ -1 +1 @@
-{"Anaemia ": 4.122422400007743, "Blood glucose increased ": 7.9578876685045135, "Blood pressure increased ": 9.312455956084708, "Concomitant disease aggravated ": 143.31916048400728, "Cough ": 3.281079737210412, "Diabetes mellitus ": 53.81031866087957, "Diabetes mellitus inadequate control ": 15.64736701682251, "Diarrhoea ": 2.119854734739539, "Drug ineffective ": 3.413064967226218, "Faeces discoloured ": 49.47961987141578, "Glucose tolerance impaired ": 115.57485983627264, "Glycosylated haemoglobin increased ": 17.48409997184417, "Hyperglycaemia ": 27.339750345512016, "Inappropriate schedule of product administration ": 8.664967430745136, "Nasopharyngitis ": 8.985880492502382, "Neoplasm malignant ": 21.03353439972257, "Nocturia ": 116.77161584677452, "Oropharyngeal pain ": 8.802529081531612, "Product use in unapproved indication ": 3.223705755156072, "Sleep apnoea syndrome ": 78.53406379154528, "Type 2 diabetes mellitus ": 23.623451677332252, "Weight increased ": 3.757924022007887}
\ No newline at end of file
+{"Acute myeloid leukaemia": 4.770223754526268, "Acute promyelocytic leukaemia": 34.86832352491992, "Agranulocytosis": 5.400041867307678, "Alopecia": 2.513743454030984, "Anaemia": 2.978470831447173, "Ascites": 2.0264143546980544, "Breast cancer": 3.0103247338890853, "Breast cancer metastatic": 4.32039000032839, "Breast cancer recurrent": 20.96213965481388, "Cardiac dysfunction": 42.873290971667046, "Cardiotoxicity": 13.079300952149048, "Colitis": 2.655044352214303, "Cytopenia": 7.43047458529351, "Disease progression": 6.247211328299993, "Disseminated intravascular coagulation": 3.0054411477035305, "Drug-induced liver injury": 4.177095161484766, "Ejection fraction decreased": 12.104541462081706, "Febrile neutropenia": 8.317356022640972, "Flushing": 2.9985932135868434, "Gastrointestinal disorder": 2.1565062695620445, "General physical health deterioration": 2.123779093164028, "Granulocyte count decreased": 8.950975550845312, "Granulocytopenia": 10.155098290692544, "Haematotoxicity": 15.127491562013253, "Hepatic function abnormal": 4.07166048630619, "Hypersensitivity pneumonitis": 18.198247742025284, "Hypothyroidism": 2.3342781242198027, "Hypoxia": 2.2256927357535754, "Immune-mediated hepatitis": 18.712096058685947, "Immune-mediated hypothyroidism": 11.46201496584662, "Infusion related reaction": 2.0721947443348614, "Interstitial lung disease": 3.267595172648825, "Invasive ductal breast carcinoma": 9.354798349180683, "Leukopenia": 7.0765629339749205, "Liver injury": 3.0279507347302164, "Malignant neoplasm progression": 9.224935846706318, "Metastases to bone": 13.182002823954797, "Metastases to central nervous system": 8.477027558357051, "Metastases to liver": 8.32848896061637, "Metastases to lung": 8.522404990230545, "Metastases to lymph nodes": 13.60697261388922, "Mucosal inflammation": 2.8878591677951824, "Myelosuppression": 42.57353739824841, "Neoplasm progression": 4.04961524736345, "Neuropathy peripheral": 6.591601146573508, "Neurotoxicity": 4.980259111635566, "Neutropenia": 7.150327048754984, "Neutrophil count decreased": 22.89454791394576, "Non-small cell lung cancer": 10.997894707503384, "Pancytopenia": 3.6361545709060583, "Pericardial effusion": 2.0323053314220214, "Peripheral sensory neuropathy": 12.865449832205602, "Platelet count decreased": 3.52739224219964, "Pleural effusion": 2.1190402236596837, "Pneumonitis": 6.586848759406368, "Polyneuropathy": 4.577187379605625, "Premature baby": 2.2583734658357515, "Product use in unapproved indication": 2.505224702757694, "Second primary malignancy": 6.264088195099037, "Septic shock": 2.573697234036233, "Therapy partial responder": 17.959005945723682, "Thrombocytopenia": 2.0614139968888203, "Thyroiditis": 7.414635514765443, "Transaminases increased": 3.3645048476009856, "White blood cell count decreased": 16.075427350488546}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/845.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/845.json
index cd68eefdd26..ff5cc713f1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/845.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/845.json
@@ -1 +1 @@
-{"Balance disorder ": 3.776642041061872, "Bradycardia ": 4.522539105533408, "COVID-19 ": 2.9767309870690646, "Confusional state ": 2.7840659761709534, "Contraindicated product administered ": 5.171335477168774, "Decreased appetite ": 2.1039853110875737, "Diarrhoea ": 2.2100780189255773, "Drug interaction ": 15.386146296622652, "Dysgeusia ": 17.681183237595107, "Feeling abnormal ": 2.7775552601216478, "Urinary tract infection ": 3.4181698885354312}
\ No newline at end of file
+{"Neuropathy peripheral": 17.53233655214487, "Off label use": 3.681596212694573, "Product use issue": 17.66970884703083, "Rash": 3.717014418106517}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/846.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/846.json
index 7f6c9c36024..437a15f2ef4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/846.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/846.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 6.005476762618425, "Alveolar soft part sarcoma ": 2393.722277868474, "Amylase increased ": 5.899918398429357, "Ascites ": 2.204751588921844, "Aspartate aminotransferase increased ": 4.96016328553554, "Blood alkaline phosphatase increased ": 2.1979120649952697, "Blood bilirubin increased ": 7.800948825404019, "Blood pressure increased ": 2.1557975006304075, "Blood pressure systolic increased ": 4.562947080318598, "Blood thyroid stimulating hormone increased ": 12.126120596847892, "Cardiac failure ": 2.169485130122355, "Clear cell renal cell carcinoma ": 376.3078547219088, "Decreased appetite ": 3.4464240193774587, "Diarrhoea ": 2.95250785084866, "Disease progression ": 4.687897009170715, "Drug-induced liver injury ": 5.510970339677155, "Ewing's sarcoma ": 190.91307841316643, "Gastrointestinal toxicity ": 14.277915741464014, "Haemoptysis ": 2.8429838048179588, "Hair colour changes ": 69.88264006999313, "Hepatic failure ": 2.9361488499410715, "Hepatic function abnormal ": 5.457018408316558, "Hepatotoxicity ": 21.881884249347717, "Hyperbilirubinaemia ": 8.237906255736153, "Hypertension ": 5.495674879670127, "Hypertransaminasaemia ": 7.294641958004463, "Hypothyroidism ": 7.411496511870068, "Intestinal perforation ": 8.819903321288153, "Jaundice ": 2.985917401333833, "Leiomyosarcoma ": 233.90928402187205, "Liver function test abnormal ": 2.583598603221104, "Liver function test increased ": 4.620312609536337, "Liver injury ": 3.2495188569297917, "Malignant neoplasm progression ": 38.95369816501778, "Metastases to bone ": 12.616916336947613, "Metastases to central nervous system ": 17.219248089598665, "Metastases to liver ": 10.105666365323083, "Metastases to lung ": 47.94854878515119, "Metastases to lymph nodes ": 18.11540227348305, "Metastases to spine ": 23.342671409656152, "Metastatic renal cell carcinoma ": 52.539787273854216, "Mucosal inflammation ": 2.913754855245118, "Neoplasm progression ": 2.3883253303420777, "Nephrotic syndrome ": 6.527876194109605, "Neutropenia ": 2.14011295883924, "Osteosarcoma metastatic ": 862.0287985077421, "Palmar-plantar erythrodysaesthesia syndrome ": 16.5570235431447, "Platelet count decreased ": 2.5470386332828068, "Pleural effusion ": 3.8665750483282393, "Pneumothorax ": 32.419494668662544, "Posterior reversible encephalopathy syndrome ": 12.325488290256157, "Product use in unapproved indication ": 8.362667981663801, "Proteinuria ": 9.60978881754176, "Pulmonary mass ": 4.235672980853655, "Renal cancer ": 3.280296527797834, "Renal cell carcinoma ": 29.374748934370736, "Soft tissue sarcoma ": 266.8290850373411, "Taste disorder ": 2.1667296057952354, "Therapeutic response decreased ": 6.040715336343409, "Therapy partial responder ": 13.153834687498836, "Thrombocytopenia ": 2.639548826243912, "Transaminases increased ": 10.601328872373006}
\ No newline at end of file
+{"Joint injury": 330.36144888742234, "Musculoskeletal pain": 135.39174423901332}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/847.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/847.json
index 193b6651569..3d710b13843 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/847.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/847.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.2665945999167167, "Agranulocytosis ": 13.683229995519577, "Anaphylactic reaction ": 2.841899556835528, "Antithrombin III decreased ": 575.9895961791626, "Coagulopathy ": 15.246538514936956, "Embolism venous ": 191.89311462798915, "Febrile neutropenia ": 15.743999083044455, "Granulocytopenia ": 22.93374745433444, "Haemoglobin decreased ": 2.150854898690236, "Hepatic function abnormal ": 2.9499715632230257, "Hypersensitivity ": 3.895219141871332, "Hypertriglyceridaemia ": 55.46322503486626, "Infection ": 3.015463228536685, "Leukopenia ": 3.1753234105710217, "Myelosuppression ": 92.99782563488202, "Neutrophil count decreased ": 7.549995066028913, "Pancreatitis ": 5.48124796280896, "Pancytopenia ": 7.840648745542014, "Platelet count decreased ": 6.097167600834943, "Thrombocytopenia ": 3.039499043319568, "Urticaria ": 2.684207431501586, "White blood cell count decreased ": 8.112431180730317}
\ No newline at end of file
+{"Febrile neutropenia": 7.63696506270799, "Haemoglobin decreased": 5.9023788002993145, "Malignant neoplasm progression": 4.67972848222079, "Neoplasm progression": 32.93367121164228, "Neutropenia": 16.458247250262247, "Neutrophil count decreased": 10.698972995350609}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/848.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/848.json
index 6b9b063f59d..df70a3284cd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/848.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/848.json
@@ -1 +1 @@
-{"Abdominal infection ": 2.394671059154865, "Abortion spontaneous ": 2.114093662417026, "Abscess ": 2.8200358057637023, "Abscess limb ": 3.1456478539677666, "Acquired haemophilia ": 3.138899803904076, "Acute psychosis ": 3.270185807663208, "Acute stress disorder ": 2.969714753494276, "Affective disorder ": 2.073042001878912, "Alanine aminotransferase abnormal ": 3.366536908045192, "Alanine aminotransferase increased ": 2.4862034969428417, "Alcohol use ": 6.55870769963997, "Alcoholism ": 2.148644745952752, "Alopecia ": 3.020918928808236, "Alopecia totalis ": 3.1805242980303534, "Alpha 1 foetoprotein increased ": 10.339133414728591, "Ammonia increased ": 8.490191464134423, "Anaemia ": 10.856081212774754, "Anaemia macrocytic ": 4.5229869174040775, "Anal fissure ": 2.238158940034937, "Anal haemorrhage ": 2.6022841428211843, "Anal inflammation ": 4.660851110761988, "Anal pruritus ": 28.45281085338077, "Anger ": 4.828531391228215, "Angular cheilitis ": 6.427978045524723, "Anorectal discomfort ": 37.35516016730588, "Anorectal disorder ": 5.565616156234569, "Anti-thyroid antibody positive ": 3.157985364535693, "Aplasia pure red cell ": 2.114870246685556, "Aplastic anaemia ": 4.636340723237672, "Appendicectomy ": 2.226816329081166, "Appetite disorder ": 2.1208590456183827, "Arthritis bacterial ": 2.023159462034352, "Ascites ": 4.447282353762029, "Aspartate aminotransferase abnormal ": 2.097610924178935, "Atypical pneumonia ": 2.232197470738288, "Autoimmune haemolytic anaemia ": 5.221186678051403, "Autoimmune hepatitis ": 4.425602181478599, "Autoimmune thyroiditis ": 4.758853497458105, "Biliary obstruction ": 2.3751071361874816, "Bipolar I disorder ": 4.610085778720421, "Bipolar disorder ": 2.7897418349701733, "Blood albumin decreased ": 2.340341314977856, "Blood bilirubin increased ": 2.3129320299976044, "Blood disorder ": 2.9058122341275303, "Blood electrolytes decreased ": 3.5058034967179688, "Blood iron increased ": 3.686231978703912, "Blood potassium abnormal ": 2.820045882152264, "Blood potassium decreased ": 3.145081888916673, "Blood test abnormal ": 2.8223681388621675, "Blood thyroid stimulating hormone decreased ": 4.843458456607736, "Blood thyroid stimulating hormone increased ": 3.965919619290296, "Blood triglycerides increased ": 2.433619121002644, "Blood uric acid increased ": 2.2211819539518656, "Bone marrow disorder ": 3.567110032805449, "Bone marrow failure ": 2.340701173798871, "Bone marrow oedema ": 2.9542107648907314, "Brain abscess ": 2.553401724187239, "Brain hypoxia ": 2.0026783142203635, "Brain stem haemorrhage ": 2.251000747453597, "Carbohydrate antigen 19-9 increased ": 4.272514641406242, "Cellulitis ": 2.1801629576672634, "Cerebellar haemorrhage ": 2.882877143779838, "Chapped lips ": 2.70185097197796, "Chorea ": 2.4858534341170944, "Chronic hepatic failure ": 8.225071437874885, "Chronic hepatitis C ": 9.53626242358278, "Clubbing ": 5.540838200373807, "Colitis ischaemic ": 3.7135905529107336, "Coma hepatic ": 2.1299743612146083, "Crying ": 2.001387773829051, "Cryoglobulinaemia ": 21.537640796997987, "Cutaneous sarcoidosis ": 8.232388210848448, "Deafness ": 2.204780301795479, "Deafness unilateral ": 2.271282694386239, "Decreased appetite ": 2.473128561778609, "Dehydration ": 2.9914671167591065, "Demyelinating polyneuropathy ": 2.397865990226409, "Dental caries ": 2.095454291685986, "Dental restoration failure ": 4.119843891416878, "Depression ": 6.374490651132759, "Depressive symptom ": 2.622464177618415, "Dermal cyst ": 2.4183025313187896, "Dermatitis ": 2.3261861166993985, "Dermatitis infected ": 7.027374826211197, "Diabetes mellitus ": 2.036904087521839, "Drug specific antibody absent ": 2.7744894909161397, "Dry skin ": 5.326728429618185, "Dyschezia ": 3.7787155897268376, "Dysgeusia ": 2.6576526095404804, "Emotional disorder ": 2.4549170492396573, "Empyema ": 2.555324873058888, "Endocarditis ": 3.8035423732818976, "Endocarditis bacterial ": 3.966557141860426, "Endodontic procedure ": 3.844208586611816, "Eosinophil count decreased ": 2.1210880057740438, "Erythema nodosum ": 2.434671991097386, "Escherichia sepsis ": 2.921100836387362, "Exposure via body fluid ": 2.433652797289394, "Exposure via skin contact ": 2.6800920082488298, "Failure to thrive ": 4.895895703818265, "Fat tissue increased ": 2.1568549551210863, "Fibrosis ": 2.5639962661187194, "Full blood count abnormal ": 2.665764304262987, "Full blood count decreased ": 8.724457781966105, "Furuncle ": 2.5750134696979226, "Gallbladder polyp ": 3.80025163421434, "Gastric pH decreased ": 2.872197029649099, "Gingival bleeding ": 3.71265382402777, "Gingival pain ": 2.3317856275493303, "Granulocyte count decreased ": 7.660713173576283, "Granulocytopenia ": 5.520841947653116, "Granulomatous liver disease ": 4.532703579706318, "Graves' disease ": 4.517214762417995, "Gravitational oedema ": 2.6643805846401776, "Haemangioma of liver ": 3.0180354213133453, "Haematemesis ": 2.233979819319233, "Haematocrit abnormal ": 5.25921771551082, "Haematocrit decreased ": 6.866375065843592, "Haematology test abnormal ": 8.399116914428886, "Haemochromatosis ": 8.25056931707855, "Haemoglobin ": 20.63941900416405, "Haemoglobin abnormal ": 4.651654299375388, "Haemoglobin decreased ": 9.655638470666378, "Haemolytic anaemia ": 8.697255856136703, "Haemorrhoidal haemorrhage ": 2.493162542268886, "Haemorrhoids ": 4.931697417775261, "Haemorrhoids thrombosed ": 3.2380903027789647, "Hand dermatitis ": 2.356356897487794, "Hepatic cancer ": 2.730850008307717, "Hepatic cancer recurrent ": 8.891482554877246, "Hepatic cirrhosis ": 10.55538089373633, "Hepatic encephalopathy ": 5.130926981523602, "Hepatic failure ": 3.443414651590041, "Hepatic fibrosis ": 4.754606118452727, "Hepatic mass ": 3.794014914531565, "Hepatic neoplasm ": 3.3080952244922788, "Hepatic pain ": 8.362370050043396, "Hepatitis B DNA increased ": 3.472633003225663, "Hepatitis B surface antigen positive ": 13.26700719516867, "Hepatitis C ": 10.999716272042145, "Hepatitis C RNA increased ": 29.76771912571276, "Hepatitis C RNA positive ": 17.49627553969152, "Hepatitis C virus test ": 40.57473560326963, "Hepatitis C virus test positive ": 11.618981624459783, "Hepatocellular carcinoma ": 2.308174788477719, "Hepatorenal failure ": 5.791091835619644, "Homicidal ideation ": 11.84520654733562, "Homicide ": 2.7195326283713595, "Hyperparathyroidism ": 6.265516394401678, "Hyperthyroidism ": 6.011153763663096, "Hypothyroidism ": 5.313897539842043, "Immune thrombocytopenia ": 3.4697071477254227, "Impatience ": 3.646684457617973, "Infected cyst ": 5.59189523804532, "Infected skin ulcer ": 2.1984251621212323, "Infertility ": 2.906384737347863, "Injection site bruising ": 3.0045083914284625, "Injection site infection ": 3.627809809232158, "Injection site rash ": 4.488240407203239, "Injection site ulcer ": 2.5739437988065528, "Insomnia ": 3.0587966948514373, "Intercepted product storage error ": 35.60219331159884, "Interstitial lung disease ": 3.715013316673896, "Iron overload ": 3.2150869425324564, "Irritability ": 5.051250139894244, "Klebsiella bacteraemia ": 3.1353055812921675, "Laboratory test abnormal ": 2.6750691600372205, "Leukopenia ": 5.398825452045159, "Limb mass ": 2.6378063666562963, "Liver tenderness ": 4.323495871313302, "Liver transplant ": 2.4687698225527845, "Liver transplant rejection ": 3.294369690463115, "Loose tooth ": 2.891460078326796, "Lung abscess ": 2.005352668416377, "Lymph node tuberculosis ": 2.949003532312677, "Lymphocyte count increased ": 3.182507242259926, "Macrocytosis ": 3.1822239735592426, "Major depression ": 2.599668333410378, "Mass ": 2.1574938055007142, "Memory impairment ": 2.35219547194414, "Meningitis viral ": 2.343774189009945, "Mental disorder ": 2.5043278693789026, "Mononeuropathy multiplex ": 5.523378368757425, "Mood altered ": 3.9170019104844354, "Mood swings ": 3.773605450971736, "Mouth injury ": 2.0821070060505384, "Muscle abscess ": 4.729710007216791, "Nasal ulcer ": 3.2651175792031752, "Nephrotic syndrome ": 2.2435592816047065, "Nervousness ": 2.1920055466226738, "Neutropenia ": 4.936914367766404, "Neutrophil count abnormal ": 5.209846730989928, "Neutrophil count decreased ": 8.76777296289789, "No adverse event ": 3.959864859315759, "Ocular vascular disorder ": 3.534021348166976, "Oesophageal varices haemorrhage ": 7.543699955078122, "Optic ischaemic neuropathy ": 4.439784482206279, "Optic neuritis ": 2.159315863619944, "Optic neuropathy ": 2.4748696296274693, "Oral fungal infection ": 3.160035187627252, "Oral infection ": 3.1820411826383297, "Oral lichen planus ": 2.498449708420172, "Oral mucosal blistering ": 3.297024115683356, "Osmotic demyelination syndrome ": 7.2797245048246015, "Pancytopenia ": 5.848013727865227, "Papilloedema ": 2.7331147756334957, "Paranoia ": 3.679762711832305, "Paternal exposure timing unspecified ": 8.31624681105071, "Peripheral motor neuropathy ": 2.9221716322032134, "Peripheral sensorimotor neuropathy ": 2.0087261054667325, "Peritonitis bacterial ": 3.8031219938512897, "Peroneal nerve palsy ": 2.3608292066645986, "Pharyngeal disorder ": 2.8197355795100525, "Pharyngeal ulceration ": 5.874985072507446, "Physical assault ": 2.0237567444924363, "Platelet count abnormal ": 4.764929184154894, "Platelet count decreased ": 9.857234295713363, "Platelet disorder ": 4.254657659778611, "Pleurisy ": 2.493331852741769, "Pneumococcal sepsis ": 3.7472211405682647, "Pneumonia pneumococcal ": 2.442649027553118, "Pneumonia staphylococcal ": 2.957090187807436, "Pneumonia streptococcal ": 7.061844426530764, "Polymyositis ": 6.100394054249318, "Porphyria non-acute ": 16.16536088612806, "Portal hypertension ": 5.313027487976421, "Pregnancy of partner ": 12.513707960459236, "Procedural complication ": 2.394694919680528, "Proctalgia ": 6.765729653415421, "Product counterfeit ": 2.4270704554170552, "Prurigo ": 3.3932990885150165, "Psoas abscess ": 4.096950187522695, "Psoriasis ": 2.3397961595430514, "Psychotic disorder ": 4.165478632477139, "Pulmonary granuloma ": 2.546950649512058, "Pulmonary sarcoidosis ": 8.894496582030062, "Pulmonary tuberculosis ": 2.913748357730022, "Rash ": 2.0168070429978293, "Rectal abscess ": 5.259920454766123, "Red blood cell abnormality ": 6.155601416996599, "Red blood cell count abnormal ": 3.7122073522632566, "Red blood cell count decreased ": 19.262463026304136, "Red blood cell count increased ": 2.1716365869484715, "Red blood cell morphology abnormal ": 20.63941900416405, "Red blood cell transfusion ": 2.3889335889434657, "Respiratory tract congestion ": 2.5453298115621683, "Reticulocyte count decreased ": 3.308455097905944, "Retinal artery thrombosis ": 4.077166531413983, "Retinal detachment ": 4.440742394406674, "Retinal disorder ": 3.690120327247411, "Retinal exudates ": 36.38676998837902, "Retinal haemorrhage ": 8.884964568376708, "Retinal injury ": 2.335385519740654, "Retinal ischaemia ": 3.854736152723765, "Retinal tear ": 2.89043483767409, "Retinal vascular thrombosis ": 2.4073594416780324, "Retinal vein thrombosis ": 3.852955619705516, "Retinitis ": 3.638104008018494, "Retinopathy ": 13.870868379099276, "Saliva altered ": 2.2615832925699286, "Salmonellosis ": 4.93995077456119, "Sarcoidosis ": 14.46405046873486, "Scrotal swelling ": 2.8410989769345627, "Self-injurious ideation ": 5.67433429611298, "Sepsis ": 2.259438918384433, "Serum ferritin increased ": 3.3735598977719947, "Sjogren's syndrome ": 2.075421285968232, "Skin fissures ": 3.6001088599828157, "Skin infection ": 2.1935926577847207, "Skin laceration ": 2.036222775639738, "Skin ulcer ": 3.695326758901957, "Splenomegaly ": 3.061192303909928, "Spondylitis ": 2.3040922480987542, "Spontaneous bacterial peritonitis ": 19.099931836037594, "Sputum abnormal ": 2.8273863177485663, "Staphylococcal infection ": 3.1196453740335053, "Staphylococcal sepsis ": 3.9824985413981504, "Staphylococcal skin infection ": 7.225551169262287, "Subcutaneous abscess ": 2.2214322708335352, "Sudden hearing loss ": 2.162228198410713, "Sudden visual loss ": 6.140997253798575, "Suicidal ideation ": 4.10570553554784, "Taste disorder ": 2.2379391352285785, "Testicular swelling ": 3.4487037979944333, "Therapeutic product ineffective ": 4.127230288387025, "Therapeutic response delayed ": 2.0026783142203635, "Therapy non-responder ": 3.5095080434469907, "Thinking abnormal ": 2.238463428566778, "Thrombocytopenia ": 4.416026190709739, "Thrombocytopenic purpura ": 3.114171628324546, "Thrombotic thrombocytopenic purpura ": 3.595159884021149, "Thyroid disorder ": 4.371569488329394, "Thyroid function test abnormal ": 9.533002508274675, "Thyroid hormones increased ": 4.458305022485583, "Thyroiditis ": 5.011843303437852, "Thyroiditis acute ": 5.4604569705428805, "Thyroxine increased ": 3.674212625672781, "Tongue disorder ": 2.371113596964113, "Tongue erythema ": 2.197327208547188, "Tooth abscess ": 2.544499742450005, "Tooth infection ": 2.2149747826574537, "Toxic shock syndrome ": 5.732189841457928, "Transfusion ": 8.967226893388936, "Trisomy 21 ": 2.6579682507136004, "Tuberculin test positive ": 2.172627861645715, "Tuberculosis ": 2.311289699114206, "Tuberculous pleurisy ": 4.891064107128184, "Tympanic membrane perforation ": 2.180159899447024, "Type 1 diabetes mellitus ": 5.593327030678427, "Underweight ": 2.474092611415737, "Urosepsis ": 2.496483875191424, "Varices oesophageal ": 13.218864828360244, "Violence-related symptom ": 4.367869339207155, "Viral load decreased ": 16.132272360540007, "Viral load increased ": 22.90058888141333, "Viral test positive ": 4.785999630580513, "Virologic failure ": 2.1131899223825954, "Vision blurred ": 2.05337653587614, "Vogt-Koyanagi-Harada disease ": 10.081442698463515, "Weight decreased ": 4.122401412320108, "White blood cell count abnormal ": 3.66934892534104, "White blood cell count decreased ": 14.329082505493377, "White blood cell disorder ": 7.37444050070655}
\ No newline at end of file
+{"Agitation": 4.417861392365098, "Alanine aminotransferase increased": 3.1201835625851184, "Altered state of consciousness": 5.854295983308866, "Anxiety": 2.349022033762413, "Aspartate aminotransferase increased": 3.1496770467135624, "Blood creatine phosphokinase increased": 5.758346355844452, "Cardiac arrest": 3.400350905701708, "Completed suicide": 6.398956770838945, "Confusional state": 2.0147222200434007, "Constipation": 2.946819102052445, "Delusion": 20.998724996593538, "Depression": 3.146461521521919, "Drug abuse": 3.801343130606583, "Drug interaction": 5.884099235935408, "Extrapyramidal disorder": 34.98160331614806, "Hallucination": 4.432568208933654, "Intentional product misuse": 3.538349011329053, "Mental status changes": 14.321456635387635, "Muscle rigidity": 33.29453172440556, "Myocarditis": 6.188728971692331, "Neuroleptic malignant syndrome": 45.18296401804053, "Platelet count decreased": 2.02110970608891, "Schizophrenia": 30.07224782992016, "Sinus tachycardia": 17.46551794281048, "Toxicity to various agents": 8.912159776758319, "Troponin increased": 33.06369737596907}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/849.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/849.json
index b56aaac925d..25e7e69493c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/849.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/849.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.2689764200619247, "Agranulocytosis ": 2.809958748333007, "Anaemia ": 2.814067266152577, "Anaphylactic reaction ": 2.145119190993866, "Aortitis ": 613.5579472683735, "Arrhythmia ": 5.632229392640844, "Blood lactate dehydrogenase increased ": 18.46529312678713, "Bone pain ": 26.96172059293343, "Bronchitis ": 4.748375636996808, "C-reactive protein increased ": 10.39945341041051, "Embolism ": 21.819417677679464, "Febrile neutropenia ": 49.12868073982738, "General physical health deterioration ": 7.686962778184768, "Infection ": 4.571167718882419, "Leukocytosis ": 11.068767733409931, "Leukopenia ": 8.335218267401745, "Mucosal inflammation ": 13.12904535157648, "Myelosuppression ": 2.175068292087747, "Neutropenia ": 11.04271500012666, "Neutrophil count decreased ": 13.693435977510296, "Pneumonia ": 3.004271124115495, "Pulmonary embolism ": 3.4296730116728518, "Pulmonary thrombosis ": 17.390031690283337, "Sepsis ": 5.571065086426875, "Stomatitis ": 2.6350230536707504, "Thrombocytopenia ": 4.760673530303117, "Urinary tract infection ": 4.063659520204881, "Vasculitis ": 10.577852194339638, "White blood cell count decreased ": 4.027264239750097}
\ No newline at end of file
+{"Myelosuppression": 25.27011654010468}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/85.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/85.json
index f57135c0ffa..7fa3064b015 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/85.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/85.json
@@ -1 +1 @@
-{"Abdominal distension ": 2.102098540673646, "Abnormal behaviour ": 7.656193957164304, "Aggression ": 4.091737896443417, "Agitation ": 3.16552049140356, "Decreased interest ": 41.17722194602349, "Dehydration ": 2.361467071903381, "Drug interaction ": 2.8139688350245, "Exposure during pregnancy ": 4.752764445805536, "Fear ": 8.642087545705975, "Hallucination, auditory ": 7.925452504116055, "Hypokalaemia ": 2.498696863856688, "Inappropriate affect ": 96.89138874033952, "Intentional product misuse ": 2.0501502427803837, "Irritability ": 2.3182879642361813, "Live birth ": 24.482197729375407, "Lung disorder ": 5.23722881344897, "Maternal exposure during pregnancy ": 3.256675899068878, "Memory impairment ": 2.291643309185935, "Mental status changes ": 16.5333227963875, "Normal newborn ": 32.74166895002574, "Paranoia ": 26.71934929252364, "Pneumonia ": 2.4517125532394286, "Premature baby ": 4.105853583309913, "Respiratory failure ": 2.812617853814052, "Social avoidant behaviour ": 29.35255761224113, "Substance abuse ": 8.95778877498611, "Substance-induced psychotic disorder ": 64.38417378455624, "Urinary tract infection ": 4.69448113040033}
\ No newline at end of file
+{"Pruritus": 27.77937175307699, "Rash": 21.00241000974256}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/850.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/850.json
index 1b41ce6abf1..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/850.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/850.json
@@ -1 +1 @@
-{"Abdominal tenderness ": 2.05175768503502, "Adverse event ": 2.486045021160743, "Alanine aminotransferase increased ": 2.1932950732357, "Alopecia totalis ": 24.299120254590505, "Alopecia universalis ": 86.02430164649437, "Anaemia ": 18.12663363403021, "Anal haemorrhage ": 6.423823976199437, "Anal pruritus ": 67.68052608117532, "Angiotensin converting enzyme increased ": 70.14436932856873, "Anorectal discomfort ": 30.33917692142135, "Anorectal disorder ": 8.284601741361508, "Aplasia pure red cell ": 7.73264308463609, "Aplastic anaemia ": 7.197434266897775, "Ascites ": 3.7841851538138807, "Autoimmune haemolytic anaemia ": 8.787393852965156, "Autoimmune hepatitis ": 12.574081858862918, "Autoimmune thyroiditis ": 9.667195420543443, "Bilirubin conjugated increased ": 4.750818852246233, "Blood bilirubin increased ": 2.3208578132636024, "Blood creatinine increased ": 2.1289510188418657, "Blood disorder ": 9.098414215858968, "Blood urea increased ": 2.052053170207212, "Blood uric acid increased ": 4.5403269253159015, "Bone marrow failure ": 3.902716244180676, "Chronic hepatitis C ": 87.96849830878531, "Coeliac disease ": 2.0860795364404403, "Colitis ischaemic ": 4.380923873031978, "Cryoglobulinaemia ": 27.820140695207844, "Cutaneous sarcoidosis ": 80.12832841453931, "Cutaneous vasculitis ": 2.0604717485991317, "Cytopenia ": 4.204027216059306, "Deafness neurosensory ": 9.773174139675096, "Decreased appetite ": 2.593341374186155, "Depression ": 4.292448384359702, "Dermatitis ": 2.5641203226093623, "Disease recurrence ": 2.278641552618645, "Drug eruption ": 4.110204965752982, "Drug reaction with eosinophilia and systemic symptoms ": 11.392028513729947, "Dry skin ": 4.629284477818826, "Erysipelas ": 2.00152995649778, "Erythema multiforme ": 3.9199138697663782, "Escherichia infection ": 5.899741271473969, "Factor VIII inhibition ": 4.734202100470303, "Glomerular filtration rate decreased ": 2.972268343849347, "Granuloma ": 5.031263637677742, "Graves' disease ": 7.60540509998259, "Haemoglobin decreased ": 9.07603874253652, "Haemolysis ": 2.2511420796755077, "Haemolytic anaemia ": 7.266141775465452, "Haemorrhoidal haemorrhage ": 7.772747236671253, "Haemorrhoids ": 9.805466173611904, "Hepatic cancer ": 2.6258783517408126, "Hepatic cirrhosis ": 5.24890516232784, "Hepatic encephalopathy ": 6.438705734719675, "Hepatic failure ": 5.390482336424336, "Hepatic pain ": 3.140197980507461, "Hepatitis C ": 31.911282572903563, "Hepatitis chronic active ": 51.8312100964621, "Hepatocellular carcinoma ": 6.808505291656262, "Hepatorenal syndrome ": 10.755862477019967, "Hyperbilirubinaemia ": 4.504520115829125, "Hyperthyroidism ": 5.790279601059841, "Hyperuricaemia ": 23.365808676321887, "Hypothyroidism ": 2.484518463119456, "Hypovolaemia ": 2.757941523948967, "Immune thrombocytopenia ": 4.159875894222123, "Injection site necrosis ": 6.651264214852836, "Interstitial lung disease ": 2.073324629199424, "Irritability ": 2.3774481633318847, "Leukopenia ": 8.592014690829139, "Liver transplant ": 9.091632786840236, "Liver transplant failure ": 216.20921605597152, "Liver transplant rejection ": 13.699027567553191, "Lung infiltration ": 3.349489498541369, "Lymph node tuberculosis ": 27.136394997868923, "Lymphadenopathy mediastinal ": 5.910927332641744, "Lymphopenia ": 3.106132958839261, "Major depression ": 2.7815453689361043, "Mental disorder ": 3.125436440683549, "Monocyte count increased ": 5.066591548712127, "Mood altered ": 3.1912271811445683, "Mouth ulceration ": 3.348314523951591, "Myasthenia gravis ": 2.538010425065013, "Mycobacterium abscessus infection ": 39.40274218024246, "Neutropenia ": 5.444309064908002, "Neutrophil count decreased ": 2.188947101101673, "Oesophageal candidiasis ": 3.590199469276407, "Optic ischaemic neuropathy ": 6.866297589043155, "Optic neuropathy ": 9.950603839118072, "Oral candidiasis ": 2.384868751403672, "Oral disorder ": 3.681851384405282, "Organising pneumonia ": 3.297238594525865, "Pancreatitis acute ": 2.693064518090718, "Pancytopenia ": 6.1828429366359225, "Papule ": 2.158713462508949, "Platelet count decreased ": 4.439588413347259, "Porphyria non-acute ": 41.67349272695679, "Proctalgia ": 13.737783149482118, "Pruritus ": 2.547932403338558, "Psoriasis ": 2.5079651191003878, "Psychotic disorder ": 3.820405327661158, "Pulmonary sarcoidosis ": 44.70135045759712, "Pulmonary tuberculosis ": 9.361609573384415, "Rales ": 2.1896283999018222, "Rash ": 3.293465344417725, "Red blood cell count decreased ": 2.1769398448989614, "Red blood cell transfusion ": 11.510305786449738, "Renal impairment ": 2.4327356714257933, "Retinal exudates ": 64.12214875453809, "Retinal haemorrhage ": 8.071470233191773, "Retinal ischaemia ": 87.61303857610712, "Retinal vein occlusion ": 3.3561024058885565, "Retinopathy ": 46.848390521921615, "Sarcoidosis ": 38.58698353506783, "Sepsis ": 2.4544871203342327, "Serum ferritin increased ": 4.434013604529469, "Skin hyperpigmentation ": 2.8590961768122565, "Skin lesion ": 2.376360741241249, "Skin mass ": 2.8792148646658746, "Skin plaque ": 6.559127872448173, "Skin reaction ": 2.527961094190675, "Skin ulcer ": 2.9075215145798965, "Spontaneous bacterial peritonitis ": 21.26076367312149, "Staphylococcal bacteraemia ": 5.882792861410981, "Staphylococcal sepsis ": 4.902448837393527, "Stevens-Johnson syndrome ": 2.3941538326788865, "Sudden hearing loss ": 2.9991412085072646, "Therapy non-responder ": 7.352327101590116, "Thrombocytopenia ": 6.69414669382517, "Thrombotic thrombocytopenic purpura ": 4.45445813904927, "Thyroiditis ": 3.3266136747177044, "Toxic skin eruption ": 3.906682617415401, "Transaminases increased ": 2.1330957442382337, "Transfusion ": 10.60633124393717, "Transplant failure ": 9.662342030301026, "Transplant rejection ": 3.826532961537925, "Treatment failure ": 4.141818999594627, "Tuberculosis ": 3.5212570658391678, "Type 1 diabetes mellitus ": 7.587471402362171, "Urosepsis ": 2.5348248441830563, "Viraemia ": 12.363230589761692, "Viral load increased ": 6.039716537112199, "Virologic failure ": 15.943060221728189, "Visual acuity reduced ": 2.4734504262372723, "Vogt-Koyanagi-Harada disease ": 38.49693201227187, "Weight decreased ": 3.0624903048551, "White blood cell count decreased ": 3.2334232606248388}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/851.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/851.json
index e013f6469a7..441b2fa9ab2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/851.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/851.json
@@ -1 +1 @@
-{"Abnormal sensation in eye ": 2.084322590103024, "Abortion induced ": 7.867377124620278, "Abortion spontaneous ": 2.320057112257917, "Abscess ": 3.824662725041792, "Acute psychosis ": 5.606059565663121, "Acute respiratory distress syndrome ": 3.177103189258625, "Adverse event ": 2.0007126100283528, "Affect lability ": 2.0667101406331296, "Aggression ": 3.2070435027517714, "Alcohol abuse ": 2.522592023484853, "Alcoholism ": 10.367670195178016, "Alopecia ": 2.475212123268486, "Alopecia universalis ": 9.122425473278778, "Alveolitis ": 4.49384184019817, "Ammonia increased ": 3.3838107428023614, "Amnesia ": 2.071123063389523, "Anaemia ": 9.990574269084108, "Anaemia macrocytic ": 2.887803207817908, "Anal pruritus ": 3.9272887637429887, "Anger ": 3.96912224177088, "Anorectal discomfort ": 3.7577784435142942, "Anti-neutrophil cytoplasmic antibody positive vasculitis ": 4.091608767835779, "Anti-thyroid antibody positive ": 7.516104243376881, "Aplasia pure red cell ": 6.453376607821674, "Appendicitis ": 5.360149010088953, "Appetite disorder ": 2.3135784099238754, "Arthritis bacterial ": 2.976347410812122, "Ascites ": 3.2844314620525217, "Autoimmune haemolytic anaemia ": 4.711918642980698, "Autoimmune hepatitis ": 8.120395641296605, "Autoimmune thyroiditis ": 5.786724383722938, "Azotaemia ": 2.006257349114239, "B-cell lymphoma ": 2.109318584747225, "Bacterial sepsis ": 2.7708975411929413, "Bipolar I disorder ": 4.966625361874993, "Bladder spasm ": 5.88492601916547, "Blood bilirubin increased ": 2.3804710663731603, "Blood disorder ": 7.340849029817821, "Blood potassium decreased ": 3.25666084427149, "Blood thyroid stimulating hormone abnormal ": 7.516104243376881, "Blood thyroid stimulating hormone decreased ": 2.865633780662524, "Blood thyroid stimulating hormone increased ": 2.6907482269227407, "Blood uric acid increased ": 6.849380935879915, "Brain abscess ": 2.833479219816101, "CD4 lymphocytes decreased ": 4.0338954823160815, "Cardiomyopathy ": 2.1187359744430783, "Cellulitis ": 2.522573468139489, "Cerebellar infarction ": 4.459796079300907, "Cerebral haemorrhage ": 2.540970976298055, "Cerebral infarction ": 2.8655319410860622, "Chapped lips ": 2.800322583820305, "Cholecystectomy ": 2.655286764176956, "Chronic inflammatory demyelinating polyradiculoneuropathy ": 4.511070856971684, "Colitis ischaemic ": 11.214496666626587, "Connective tissue disorder ": 11.53237051439903, "Coombs positive haemolytic anaemia ": 11.21888842208301, "Cryoglobulinaemia ": 28.02724341520697, "Cutaneous sarcoidosis ": 8.350869435698465, "Deafness ": 2.2004023581835623, "Deafness neurosensory ": 2.7178549290624803, "Decreased appetite ": 3.267920827939701, "Decreased immune responsiveness ": 3.022503091221117, "Dehydration ": 3.4292589433707006, "Delusion ": 2.635276954199362, "Depression ": 4.686396471036185, "Depressive symptom ": 18.02828028460847, "Diabetes mellitus ": 4.677338784516457, "Diabetic ketosis ": 6.195044171748146, "Disseminated intravascular coagulation ": 2.8599875684713667, "Drug eruption ": 4.672010911985311, "Drug exposure before pregnancy ": 8.69825360655664, "Dry mouth ": 2.065606381219386, "Dry skin ": 3.585168494221376, "Dysgeusia ": 4.881739417072375, "Eczema asteatotic ": 8.603176086683266, "Encephalopathy ": 2.280285349255256, "Enteritis infectious ": 8.562411264644265, "Enterocolitis haemorrhagic ": 2.1140361391768483, "Erythema multiforme ": 3.441690826109807, "Escherichia sepsis ": 2.268377086942889, "Exposure via body fluid ": 27.624750342598524, "Facial paralysis ": 2.5092059960530646, "Feeding disorder ": 2.0230253038636388, "Fluid intake reduced ": 2.172692381010178, "Fluid replacement ": 15.2184793924201, "Gastrointestinal infection ": 3.210533593246148, "Gingival bleeding ": 3.036156598972957, "Goitre ": 3.4144234193954053, "Granulocytopenia ": 2.4157308133168165, "Graves' disease ": 12.593643762371324, "Haematocrit decreased ": 2.933802179443729, "Haemoglobin abnormal ": 2.26491664928827, "Haemoglobin decreased ": 7.68179900267006, "Haemolysis ": 2.482441073657569, "Haemolytic anaemia ": 7.391910526407071, "Haemorrhagic cerebral infarction ": 6.815147075760715, "Haemorrhoidal haemorrhage ": 2.5254171607097837, "Hair texture abnormal ": 2.5563502465571144, "Hepatic artery stenosis ": 65.52921356671662, "Hepatic cancer ": 2.160604981712785, "Hepatic cirrhosis ": 6.160783178397923, "Hepatic encephalopathy ": 6.377218557353179, "Hepatic failure ": 2.241652016966446, "Hepatic fibrosis ": 3.994828936692246, "Hepatic mass ": 3.5459208449778123, "Hepatic neoplasm ": 3.539833829639244, "Hepatic pain ": 4.081818816527785, "Hepatitis C ": 5.7032020278508, "Hepatitis C RNA increased ": 18.03834365547028, "Hepatocellular carcinoma ": 2.463860480363384, "Hepatorenal syndrome ": 5.677108487319266, "Homicidal ideation ": 16.966296080411045, "Homicide ": 10.86144446340948, "Hyaluronic acid increased ": 229.9380837770497, "Hypersensitivity pneumonitis ": 2.632444135533732, "Hyperthyroidism ": 8.831558827005379, "Hyperuricaemia ": 24.50673824102144, "Hypoacusis ": 3.0076588118825054, "Hypoalbuminaemia ": 2.078539569897931, "Hypothyroidism ": 5.864273946906122, "Immune thrombocytopenia ": 2.62063852971095, "Infection reactivation ": 14.047558024561583, "Influenza like illness ": 2.0285873433263046, "Injection site abscess ": 9.707400605901418, "Injection site cellulitis ": 13.684776272772432, "Injection site discolouration ": 3.286596304190232, "Injection site infection ": 6.618334975687935, "Injection site necrosis ": 41.4015605968823, "Injection site rash ": 5.529265529774063, "Injection site reaction ": 2.814292652181166, "Injection site ulcer ": 54.40757624041827, "Injection site vesicles ": 2.89159128554541, "Insomnia ": 2.478233936671585, "Interstitial lung disease ": 5.369333950365591, "Intervertebral discitis ": 5.502203486851474, "Intracranial aneurysm ": 4.749091614008878, "Irritability ": 3.651052494354712, "Jaundice ": 2.387202274608553, "Lacunar infarction ": 2.118287269868794, "Leukopenia ": 5.24453041822838, "Lip dry ": 2.605827300433849, "Liver transplant ": 6.172533444558133, "Liver transplant rejection ": 6.073202179948938, "Lung infiltration ": 3.834235648844026, "Lymph node tuberculosis ": 6.254891066078447, "Lymphatic disorder ": 15.5253665329719, "Lymphoma ": 3.008843057415183, "Mallory-Weiss syndrome ": 5.054866311248769, "Malnutrition ": 2.100944198813491, "Mania ": 2.4160397795734907, "Mean cell volume increased ": 5.502575046946735, "Memory impairment ": 2.933787384267375, "Meningitis bacterial ": 3.074499234801986, "Mental disorder ": 3.084396250006178, "Mental status changes ": 3.210409064732784, "Mononeuropathy multiplex ": 13.961157350823347, "Mood altered ": 2.5368567787863925, "Mood swings ": 3.3228463373999326, "Muscle abscess ": 8.03650631955333, "Muscle atrophy ": 2.279827764167504, "Musculoskeletal disorder ": 3.5864156883165847, "Necrotising fasciitis ": 3.515391834048868, "Nervousness ": 2.281610054257478, "Neurosis ": 11.744435572666768, "Neutropenia ": 2.937445766229771, "Neutrophil count decreased ": 3.182234615391523, "Non-cardiac chest pain ": 2.7152423874740137, "Normocytic anaemia ": 3.962046917388971, "Oesophageal varices haemorrhage ": 3.1623683826218723, "Optic ischaemic neuropathy ": 7.8836263184468995, "Optic nerve disorder ": 5.08671583400806, "Optic neuritis ": 5.74878954844395, "Optic neuropathy ": 8.783995469735185, "Pancreatic disorder ": 2.273628560753431, "Pancreatitis acute ": 2.2729548882269266, "Pancytopenia ": 4.301841055928266, "Papilloedema ": 6.061506012587965, "Paranoia ": 4.397214970717138, "Paternal exposure timing unspecified ": 9.640458377205611, "Peritoneal tuberculosis ": 20.86643233759957, "Peritonitis ": 2.3135606293766737, "Peritonitis bacterial ": 11.375328909316169, "Peroneal nerve palsy ": 4.7922438923996005, "Platelet count decreased ": 5.639694258630891, "Pleurisy ": 2.2881452715823616, "Pneumonia staphylococcal ": 4.110125124260783, "Polymyositis ": 4.003886628389784, "Portal vein thrombosis ": 2.114847633981307, "Proctalgia ": 2.199082126005491, "Product quality issue ": 3.8121735086498303, "Psoas abscess ": 8.689713970945844, "Psychiatric symptom ": 3.281670866273176, "Psychotic disorder ": 4.740014972610066, "Pulmonary sarcoidosis ": 8.498278330957756, "Pulmonary tuberculosis ": 3.2402997459025897, "Pyelonephritis ": 2.421579526196039, "Raynaud's phenomenon ": 2.2664341551497014, "Red blood cell count decreased ": 7.588078949916194, "Red blood cell transfusion ": 4.520038591047882, "Retinal artery occlusion ": 5.978729605743709, "Retinal artery thrombosis ": 16.190850188273497, "Retinal detachment ": 3.3842548095876235, "Retinal disorder ": 4.0169389983323285, "Retinal exudates ": 94.25267125992168, "Retinal haemorrhage ": 24.14369905346032, "Retinal ischaemia ": 22.977075856824367, "Retinal vascular thrombosis ": 5.725431121513322, "Retinal vein occlusion ": 11.679088892669055, "Retinal vein thrombosis ": 9.97927039068865, "Retinitis ": 4.925367400351732, "Retinopathy ": 30.705000610015883, "Sarcoidosis ": 14.531881927398729, "Sepsis ": 2.415427634791253, "Serum ferritin increased ": 2.072456724900973, "Sjogren's syndrome ": 2.178699722143336, "Skin disorder ": 2.459574525065867, "Skin necrosis ": 3.44230165991304, "Skin ulcer ": 2.3561383943173264, "Splenic infarction ": 2.61026036006261, "Spontaneous bacterial peritonitis ": 10.715034833200743, "Staphylococcal infection ": 2.660549738248412, "Staring ": 2.589372448623031, "Streptococcal infection ": 2.99569724684197, "Subarachnoid haemorrhage ": 3.3067832041759617, "Substance use ": 4.424820512520087, "Sudden hearing loss ": 5.70686964067958, "Suicidal ideation ": 3.1354626028712, "Thalamus haemorrhage ": 7.532296595928472, "Therapeutic product ineffective ": 7.002435721320284, "Thirst ": 2.452659173528025, "Thrombocytopenia ": 2.597146737202438, "Thrombotic thrombocytopenic purpura ": 4.25788171645187, "Thyroid disorder ": 3.411711297197196, "Thyroid function test abnormal ": 3.3548828495788072, "Thyroiditis ": 6.9752149101148815, "Tongue disorder ": 2.5842445354635366, "Tongue ulceration ": 3.4065075693555658, "Tooth abscess ": 2.4929345199523385, "Toxic skin eruption ": 2.357253317035293, "Transfusion ": 20.685621712119307, "Tuberculosis ": 2.0771039166099965, "Tuberculous pleurisy ": 10.374034978172435, "Tunnel vision ": 3.1594182052319075, "Type 1 diabetes mellitus ": 21.897156254167225, "Varices oesophageal ": 6.368217206785163, "Vasculitis ": 2.1351152580651007, "Violence-related symptom ": 3.662840562905101, "Viral load increased ": 3.5837865174260566, "Visual acuity reduced ": 2.2511329986056112, "Visual field defect ": 5.325001982935796, "Vogt-Koyanagi-Harada disease ": 25.70195007680612, "Weight decreased ": 4.432535373979823, "White blood cell count abnormal ": 3.894777321082533, "White blood cell count decreased ": 5.453411006971207}
\ No newline at end of file
+{"Carcinoembryonic antigen increased": 71.55271718577454, "Colorectal cancer metastatic": 179.06056635253694, "Conjunctivitis": 14.84816037599784, "Constipation": 3.746494245105028, "Decreased appetite": 2.050698649065841, "Dehydration": 2.3196815176935512, "Dermatitis acneiform": 252.1960532479539, "Diarrhoea": 2.8957011275374462, "Disease progression": 2.6827067926305115, "Drug resistance": 5.462208552802176, "Febrile neutropenia": 10.10843594832608, "Hepatic encephalopathy": 23.76121476728033, "Hyperammonaemia": 27.327104888389982, "Hypomagnesaemia": 104.78900949670944, "Interstitial lung disease": 8.23785319977784, "Leukopenia": 2.493395197021378, "Metastases to liver": 18.687314237067422, "Myelosuppression": 4.677550248368575, "Neuropathy peripheral": 18.820442600493067, "Neurotoxicity": 29.940356339272107, "Neutropenia": 11.851451098382183, "Neutrophil count decreased": 4.382190066521645, "Palmar-plantar erythrodysaesthesia syndrome": 5.486448857272092, "Paraesthesia": 2.317219159947078, "Paronychia": 236.9122316971992, "Peripheral sensory neuropathy": 38.809223758920666, "Pneumonia aspiration": 9.305473080743532, "Polyneuropathy": 17.62130888824201, "Rash": 3.522841784885403, "Rash maculo-papular": 3.111255042219162, "Rash pustular": 38.03705630434703, "Renal tubular disorder": 35.64491850837888, "Skin disorder": 12.844063465430075, "Skin toxicity": 211.4689891667936, "Stomatitis": 14.775462739678083, "Therapeutic product effect incomplete": 2.1212230937447853, "Therapy partial responder": 74.4823847479434, "Thrombocytopenia": 6.577033261540829, "Venoocclusive liver disease": 27.736317591500065}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/852.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/852.json
index 2c5fa8a6af0..20ee55b71f6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/852.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/852.json
@@ -1 +1 @@
-{"Drug ineffective ": 5.419638698076185, "Neutropenia ": 15.79702458550655}
\ No newline at end of file
+{"Abdominal distension": 2.001329821882861, "Acute generalised exanthematous pustulosis": 5.208664628467326, "Acute hepatic failure": 2.5668719692431528, "Acute kidney injury": 2.2876221566851536, "Agranulocytosis": 2.910360593664317, "Alkalosis hypochloraemic": 101.85420501229297, "Allergy to animal": 47.71046067868815, "Antineutrophil cytoplasmic antibody positive": 51.84427240868112, "Appetite disorder": 3.458481423518841, "Asthma": 2.355911525223231, "Ataxia": 5.775324858703687, "Atelectasis": 8.737328800614726, "Atrial fibrillation": 2.0440893796929718, "Atrial flutter": 2.2856471186909584, "Bladder transitional cell carcinoma": 44.16162652746288, "Blood magnesium decreased": 15.20985126319659, "Blood phosphorus decreased": 14.0116589045849, "Blood potassium decreased": 2.9536083335544427, "Blood pressure diastolic decreased": 30.93822110470322, "Blood pressure systolic decreased": 9.155965614204984, "Blood pressure systolic increased": 14.120089639178842, "Blood triglycerides increased": 3.8668006186248416, "Blood urea increased": 3.17985584938746, "Body temperature decreased": 20.31554680398081, "Breath sounds abnormal": 8.981495551403881, "Bronchial disorder": 47.211297697972405, "Bronchial obstruction": 27.153417060635853, "Bronchiectasis": 2.513683129034652, "Bronchitis": 3.1260017300503766, "Carcinoid tumour": 111.22385372846182, "Cardiac failure chronic": 8.362065254725474, "Cardiac murmur": 2.3606150213906227, "Choking": 2.0038757668069174, "Cholelithiasis": 2.03816057378182, "Cholestasis": 6.453185437236232, "Chronic obstructive pulmonary disease": 3.081143909935779, "Completed suicide": 5.552779854696427, "Coronary artery bypass": 7.93023263083567, "Creatinine renal clearance decreased": 3.621560435414464, "Crohn's disease": 2.273804501380179, "Decreased immune responsiveness": 9.79581865466779, "Dehydration": 2.61899809023027, "Dilated cardiomyopathy": 3.2643578456119187, "Disease recurrence": 5.855321372942916, "Diverticulum intestinal": 3.405110955087, "Drug interaction": 2.697854870308493, "Drug reaction with eosinophilia and systemic symptoms": 6.754905178149402, "Duodenal ulcer": 3.5516158389963133, "Dust allergy": 25.49391377440144, "Dyspnoea at rest": 7.480649097581092, "Dyspnoea exertional": 3.8979272870998014, "Ecchymosis": 3.4558652888961547, "Ejection fraction decreased": 3.983109801983315, "Electrolyte imbalance": 5.1105855358702295, "End stage renal disease": 3.82400154753504, "Eosinophilia": 7.1227566660689545, "Erythema nodosum": 11.061684725114096, "Exercise tolerance decreased": 5.140933144337856, "Eye pruritus": 3.072309767242324, "Fall": 2.09461505180768, "Fixed eruption": 6.129252355458736, "Frequent bowel movements": 3.6620865520174, "Full blood count abnormal": 6.217705174589401, "Gastric haemorrhage": 2.037425128309988, "Gastritis": 2.5351648943908094, "Gastritis fungal": 611.0907924671799, "Gastrointestinal obstruction": 16.603462478387588, "Grandiosity": 56.51229843683184, "Grip strength decreased": 4.578118763484127, "Heart rate decreased": 4.516047920148172, "Hepatic cytolysis": 6.169824543589991, "Hepatic pain": 3.808013334838306, "Hepatic steatosis": 2.088047324100467, "Hepatitis A antibody abnormal": 1129.6804875969242, "Hepatitis cholestatic": 8.28116460083992, "Hepatomegaly": 2.65942611665106, "Hip fracture": 4.701995481726397, "Hypercalcaemia": 3.462389643437967, "Hypercholesterolaemia": 2.140794171881774, "Hyperkalaemia": 2.0018345994256115, "Hypernatraemia": 6.210011231244325, "Hypocalcaemia": 7.252358808759367, "Hypokalaemia": 2.0272455186331597, "Hypomagnesaemia": 18.923508981939747, "Hyponatraemia": 5.081290576401582, "Hypopnoea": 7.8231022067609155, "Immune thrombocytopenia": 2.2240352308610585, "Implant site dehiscence": 213.64853114502495, "Implant site erosion": 101.4906427848626, "Implant site erythema": 112.80501957193523, "Implant site inflammation": 203.6820915811512, "Implant site pruritus": 453.4762013104217, "Inappropriate antidiuretic hormone secretion": 3.621512023712018, "Klebsiella test positive": 112.564806979257, "Lactic acidosis": 2.6446327572858004, "Large intestine polyp": 12.95838365711935, "Libido increased": 8.030962357682757, "Loss of personal independence in daily activities": 3.926178284698647, "Low birth weight baby": 2.83521697044234, "Lung consolidation": 8.571647810844047, "Lung disorder": 2.054796345587766, "Lung opacity": 8.597636545712723, "Lymphopenia": 2.175307964882341, "Medical device site bruise": 512.5728492782512, "Medical device site erosion": 120.36997512141625, "Medical device site erythema": 147.12300079486812, "Medical device site haemorrhage": 157.6368027625852, "Mental disorder": 7.761248695735473, "Mental impairment": 2.608377089218842, "Mitral valve incompetence": 3.511088682234445, "Mood altered": 2.554117111739907, "Muscle atrophy": 2.109019253649244, "Nasal polyps": 15.0136011593907, "Needle issue": 6.654799147621504, "Obstructive airways disorder": 6.990083199849857, "Oesophagitis": 2.9705615609590112, "Oral mucosal eruption": 7.87819038654952, "Oropharyngeal discomfort": 3.133617912349637, "Osteoarthritis": 2.0624669237222104, "Papillary renal cell carcinoma": 170.1968268076687, "Parkinson's disease": 4.845444265310926, "Persecutory delusion": 12.132434602242313, "Petechiae": 2.1811576107846555, "Platelet count increased": 3.035546984945248, "Pleuritic pain": 13.000663835424255, "Poisoning": 2.6686900756250407, "Pregnancy": 2.2399966754158616, "Premature labour": 8.189341740847231, "Productive cough": 4.824757522846892, "Pseudomembranous colitis": 7.688224126587928, "Psychiatric symptom": 3.351864447067106, "Pulmonary congestion": 2.639258865723499, "Rash maculo-papular": 6.848031407804755, "Rash pustular": 4.142917816608933, "Rebound acid hypersecretion": 201.8805340352618, "Seasonal allergy": 6.325350553613174, "Shock haemorrhagic": 2.5737017982346955, "Sleep disorder due to a general medical condition": 9.530156945897858, "Spinal stenosis": 6.450937181354753, "Suspected suicide": 13.098449687053394, "Symmetrical drug-related intertriginous and flexural exanthema": 36.51606075627482, "Therapeutic product effect incomplete": 3.3180012521308546, "Therapy cessation": 4.829008171187868, "Therapy interrupted": 5.386869642245824, "Tonsil cancer": 40.722139663883546, "Toxic epidermal necrolysis": 6.32205314947949, "Toxic skin eruption": 2.06795257596292, "Tricuspid valve incompetence": 4.349160441227806, "Troponin increased": 4.379827226792524, "Tubulointerstitial nephritis": 8.86462339544968, "Urinary incontinence": 3.346636685219095, "Ventricular hypertrophy": 38.83963982959771, "Ventricular hypokinesia": 18.00943187719358, "Vitamin B12 decreased": 36.44580727454061, "Vitamin B12 deficiency": 14.737674844347636, "Wheelchair user": 7.975089934044765, "Wheezing": 5.523094660144454}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/853.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/853.json
index 86b3b219d47..455227cc027 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/853.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/853.json
@@ -1 +1 @@
-{"Accident ": 2.472498645656977, "Acute kidney injury ": 2.466616059031439, "Adenocarcinoma ": 13.406164798044175, "Adrenal insufficiency ": 12.209168077941726, "Adrenocorticotropic hormone deficiency ": 26.99864727474692, "Adverse event ": 3.387185153110514, "Anaemia ": 2.2395681729304133, "Atelectasis ": 2.228559301944032, "Atrioventricular block complete ": 3.719383453620359, "Autoimmune colitis ": 49.98372814426921, "Autoimmune haemolytic anaemia ": 11.953762954989994, "Autoimmune hepatitis ": 14.3734381364922, "Autoimmune hypothyroidism ": 86.8681272190973, "Autoimmune nephritis ": 77.26029267063099, "Autoimmune thyroiditis ": 11.73677481739524, "Blood thyroid stimulating hormone increased ": 5.545284949608902, "Bronchiectasis ": 2.298979924993493, "Cachexia ": 4.193654564646776, "Cardiac tamponade ": 4.039961880598208, "Central nervous system lesion ": 5.045507899970961, "Cholangitis ": 3.661618814149698, "Cholangitis sclerosing ": 16.05668030423402, "Cholecystitis ": 2.176121024718049, "Colitis ": 13.47612884143322, "Colitis microscopic ": 4.974813588076522, "Conjunctivitis ": 2.2779569168929434, "Cortisol decreased ": 11.87311502579998, "Cytokine release syndrome ": 3.161227625280937, "Cytopenia ": 2.721372608881852, "Dermatitis ": 3.59109310304366, "Dermatitis bullous ": 3.4839091246619787, "Diabetic ketoacidosis ": 5.312508188414273, "Drug effective for unapproved indication ": 15.535301193842452, "Drug-induced liver injury ": 3.328505832082729, "Eastern Cooperative Oncology Group performance status worsened ": 23.19455912006784, "Emphysema ": 2.35432785203974, "Encephalitis ": 5.745775811421783, "Encephalitis autoimmune ": 24.493644340755257, "Enterocolitis ": 3.135613259331224, "Eosinophilic fasciitis ": 70.56382415727057, "Eyelid ptosis ": 4.887155769292368, "Febrile neutropenia ": 3.438972151551652, "Fulminant type 1 diabetes mellitus ": 35.50521286446824, "Gastritis ": 2.207693137752005, "Gastrointestinal toxicity ": 4.179261713500728, "General physical health deterioration ": 2.876840895024185, "Groin pain ": 2.294625599913508, "Guillain-Barre syndrome ": 3.499112921541484, "Haematotoxicity ": 4.317666568753709, "Haemophagocytic lymphohistiocytosis ": 5.397512314161308, "Hepatitis ": 7.479720119548079, "Hepatitis toxic ": 3.7612757727925183, "Hepatotoxicity ": 6.909165705241249, "Hydronephrosis ": 3.827272070429225, "Hyperthyroidism ": 7.741051333738926, "Hypertransaminasaemia ": 9.423320697365924, "Hypophysitis ": 41.53316971573458, "Hypopituitarism ": 11.891688088871067, "Hypothyroidism ": 16.805180227366627, "Immune thrombocytopenia ": 3.804977470381414, "Immune-mediated adrenal insufficiency ": 12.18187611565332, "Immune-mediated adverse reaction ": 218.3804629883757, "Immune-mediated arthritis ": 225.4212119315721, "Immune-mediated dermatitis ": 110.2914143779514, "Immune-mediated encephalitis ": 88.13259325476984, "Immune-mediated enterocolitis ": 87.02014699375799, "Immune-mediated gastritis ": 138.76480206238105, "Immune-mediated hepatic disorder ": 17.702906219432123, "Immune-mediated hepatitis ": 159.59737572674177, "Immune-mediated hyperthyroidism ": 79.05340558283008, "Immune-mediated hypophysitis ": 68.77815117475505, "Immune-mediated hypothyroidism ": 108.51083532945196, "Immune-mediated lung disease ": 252.31174980586215, "Immune-mediated myasthenia gravis ": 142.78294347950708, "Immune-mediated myocarditis ": 222.96752296417367, "Immune-mediated myositis ": 163.0249869285506, "Immune-mediated nephritis ": 97.79539167654733, "Immune-mediated neuropathy ": 76.49009480494051, "Immune-mediated pancreatitis ": 106.91384188795674, "Immune-mediated renal disorder ": 41.03041589550981, "Immune-mediated thyroiditis ": 272.9409870106071, "Immune-mediated uveitis ": 87.25310306014602, "Inappropriate schedule of product administration ": 4.670820252626418, "Interstitial lung disease ": 3.30496325809951, "Intestinal perforation ": 2.306969561045507, "Lichen planus ": 8.72861911035164, "Lichenoid keratosis ": 15.455843731148954, "Lung adenocarcinoma ": 8.450147929399304, "Lung consolidation ": 7.839506423332576, "Lymphocytic hypophysitis ": 41.1719771148286, "Malignant neoplasm progression ": 22.544986335850417, "Metastases to adrenals ": 16.600920758504564, "Metastases to central nervous system ": 2.048016328557937, "Metastases to lung ": 2.1447424190208206, "Mucosal inflammation ": 5.08786367137818, "Multi-organ disorder ": 20.00576718863162, "Myasthenia gravis ": 26.215648034731014, "Myasthenia gravis crisis ": 30.418324473380853, "Myasthenic syndrome ": 33.76937177007655, "Myocarditis ": 5.851308603952155, "Myopathy ": 2.699496723212772, "Myositis ": 17.149963639662726, "Nephritis ": 31.09587608715112, "Nephropathy toxic ": 4.4615282099775095, "Neutropenia ": 2.759050502782986, "Neutropenic sepsis ": 4.578900562803577, "Non-small cell lung cancer ": 4.549050977466058, "Non-small cell lung cancer metastatic ": 35.32621984119697, "Ocular myasthenia ": 45.98025625679719, "Off label use ": 2.2260894039320007, "Ophthalmoplegia ": 8.032282111595299, "Organising pneumonia ": 12.523307405207756, "Palmar-plantar erythrodysaesthesia syndrome ": 2.6386768565817307, "Pancytopenia ": 3.2001865606127686, "Pemphigoid ": 17.85239913267581, "Performance status decreased ": 2.689200158241418, "Pericardial effusion ": 2.186758890047929, "Pleural effusion ": 2.375550063168703, "Pneumocystis jirovecii pneumonia ": 2.3491300736374656, "Pneumonitis ": 30.10659730805594, "Pneumothorax ": 2.01628070961675, "Polyarthritis ": 17.233569810920102, "Polymyalgia rheumatica ": 13.494303455996013, "Posterior reversible encephalopathy syndrome ": 3.855960667303973, "Prescribed underdose ": 3.812801396102118, "Primary hypothyroidism ": 87.03208616193082, "Product use in unapproved indication ": 5.701699506444728, "Product use issue ": 5.152339237576816, "Proteinuria ": 4.052773951805703, "Psoriasis ": 2.412262972984238, "Pulmonary fibrosis ": 2.3439105708916537, "Pulmonary toxicity ": 8.069315406345059, "Radiotherapy ": 31.937862675345663, "Rash maculo-papular ": 2.118334824169172, "Renal cyst ": 3.613544137050373, "Renal tubular necrosis ": 8.048350806156884, "Respiratory failure ": 2.1706551005134904, "Sarcoidosis ": 8.471164720858777, "Secondary adrenocortical insufficiency ": 18.566455566098043, "Sjogren's syndrome ": 8.423800994486738, "Skin infection ": 3.2701089129512866, "Skin toxicity ": 24.193048356096604, "Stevens-Johnson syndrome ": 2.8707566242744376, "Therapy non-responder ": 6.449377838043633, "Therapy partial responder ": 97.89781064909909, "Thyroiditis ": 18.04392353236316, "Toxic epidermal necrolysis ": 5.781953473209828, "Troponin increased ": 2.3393398088714794, "Tubulointerstitial nephritis ": 15.032409516279172, "Tumour hyperprogression ": 286.3694136234043, "Tumour pseudoprogression ": 184.13392856790887, "Type 1 diabetes mellitus ": 29.26185608868576, "Uveitis ": 3.437673698302169, "Vasculitis ": 2.9312153737948616, "Vitiligo ": 44.42715331401061}
\ No newline at end of file
+{"Anaphylactic reaction": 46.28022410939269}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/854.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/854.json
index 13167a82f22..7fd750cfffc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/854.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/854.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.4589991346483107, "Adenocarcinoma ": 29.411759205478, "Anaemia ": 8.254263839702183, "Blood creatinine increased ": 2.65723815982791, "Bone marrow failure ": 3.5571300506083587, "Cytopenia ": 8.661589289839752, "Decreased appetite ": 2.0597320403413653, "Disease progression ": 8.779625294981704, "Erysipelas ": 8.459825764561852, "Eyelid oedema ": 5.943825526776097, "Febrile bone marrow aplasia ": 26.772052895399803, "Febrile neutropenia ": 9.213016454774568, "Fluid retention ": 2.3767697755699704, "Gastrointestinal toxicity ": 15.46480298601168, "General physical health deterioration ": 2.038273245465963, "Glomerular filtration rate decreased ": 2.3813590387932786, "Haematotoxicity ": 59.72475605556156, "Haemoglobin decreased ": 2.1430363265182244, "Haemoptysis ": 4.260469760728439, "Hepatic function abnormal ": 4.0343043886864685, "Hepatotoxicity ": 8.437011960379898, "Hypercreatininaemia ": 55.48299098868674, "Hypertransaminasaemia ": 6.8597886032104185, "Interstitial lung disease ": 3.037791356837816, "Kidney fibrosis ": 29.308097536992346, "Lacrimation increased ": 2.560465838973916, "Leukopenia ": 7.476794303000054, "Liver injury ": 2.278333507171818, "Lung adenocarcinoma ": 86.98840776426681, "Lung adenocarcinoma stage IV ": 142.9284234042745, "Malignant neoplasm progression ": 20.37061834568109, "Metastases to bone ": 3.4453514551195266, "Metastases to central nervous system ": 6.874710134936829, "Metastases to liver ": 2.6483612872406144, "Metastases to lung ": 3.569441367978779, "Mouth ulceration ": 2.584181272144885, "Mucosal inflammation ": 7.7321859486767535, "Myelosuppression ": 44.96270929325553, "Neoplasm progression ": 5.898010270704583, "Nephropathy toxic ": 17.20789078806694, "Neutropenia ": 10.085150629041744, "Neutropenic colitis ": 26.199465956507265, "Neutropenic sepsis ": 15.810092617644823, "Neutrophil count decreased ": 10.364620404842864, "Non-small cell lung cancer ": 29.84811142501192, "Oedema peripheral ": 2.0148124283467843, "Off label use ": 2.1542632275926006, "Osteonecrosis of jaw ": 4.687289583030724, "Ototoxicity ": 31.348768565678352, "Pancytopenia ": 10.621235728969689, "Peripheral ischaemia ": 11.482248470918138, "Platelet count decreased ": 6.5236565887887, "Pleural effusion ": 2.607980512916922, "Pneumonia ": 2.149662413314887, "Pneumonitis ": 7.623794091325042, "Pneumothorax ": 2.871185898940192, "Proteinuria ": 2.8281726182896776, "Pseudocellulitis ": 1527.0649025067391, "Pulmonary toxicity ": 7.914760144598592, "Renal impairment ": 4.191925576994509, "Renal tubular necrosis ": 13.187362614981147, "Respiratory failure ": 4.325437726915787, "Scleroderma ": 22.765918159140377, "Sepsis ": 2.422509859981268, "Skin hyperpigmentation ": 7.596153956270079, "Skin toxicity ": 16.728436226166863, "Therapeutic response decreased ": 2.603158947398427, "Therapy partial responder ": 19.845889263031644, "Thrombocytopenia ": 6.064010459598344, "Toxic epidermal necrolysis ": 3.070247010802734, "Treatment failure ": 2.949165635338668, "Tubulointerstitial nephritis ": 7.006932152896293, "White blood cell count decreased ": 7.598839570149743}
\ No newline at end of file
+{"Anaemia": 4.122422400007743, "Blood glucose increased": 7.9578876685045135, "Blood pressure increased": 9.312292485783365, "Concomitant disease aggravated": 143.31916048400728, "Cough": 3.2810493051164995, "Diabetes mellitus": 53.81031866087957, "Diabetes mellitus inadequate control": 15.64736701682251, "Diarrhoea": 2.1198370439389693, "Drug ineffective": 3.413039736075211, "Faeces discoloured": 49.47961987141578, "Glucose tolerance impaired": 115.57485983627264, "Glycosylated haemoglobin increased": 17.48409997184417, "Hyperglycaemia": 27.339750345512016, "Inappropriate schedule of product administration": 8.664967430745136, "Nasopharyngitis": 8.985195774518747, "Neoplasm malignant": 21.03353439972257, "Nocturia": 116.77161584677452, "Oropharyngeal pain": 8.802529081531612, "Product use in unapproved indication": 3.223605231981204, "Sleep apnoea syndrome": 78.49920952748595, "Type 2 diabetes mellitus": 23.623451677332252, "Weight increased": 3.757924022007887}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/855.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/855.json
index 753d3855c01..8aeacc7fe5e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/855.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/855.json
@@ -1 +1 @@
-{"Aggression ": 33.183438752010844, "Altered state of consciousness ": 12.23001555370216, "Anger ": 33.01116502743489, "Balance disorder ": 7.2792627732616015, "Drug interaction ": 5.968937727079735, "Epilepsy ": 15.057648403573708, "Gait disturbance ": 3.9467880703460914, "Intentional overdose ": 9.741663556189955, "Irritability ": 17.189651770743307, "Multiple-drug resistance ": 151.4527106111148, "Off label use ": 2.142332320174703, "Partial seizures ": 45.44369259789571, "Pneumonia aspiration ": 20.82629814709234, "Product use in unapproved indication ": 3.702873554639356, "Seizure ": 5.877154859472207, "Somnolence ": 3.51008302730924, "Suicidal ideation ": 4.93186003540748, "Suicide attempt ": 8.905146422301383}
\ No newline at end of file
+{"Balance disorder": 3.776642041061872, "Bradycardia": 4.522397380021607, "COVID-19": 2.976714753531481, "Confusional state": 2.7840659761709534, "Contraindicated product administered": 5.171335477168774, "Decreased appetite": 2.1039649034995107, "Diarrhoea": 2.21005957441302, "Drug interaction": 15.386146296622652, "Dysgeusia": 17.681183237595107, "Feeling abnormal": 2.777501801957724, "Urinary tract infection": 3.4181698885354312}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/856.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/856.json
index 129ae13b55f..ebd7d07050f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/856.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/856.json
@@ -1 +1 @@
-{"Anaphylactic reaction ": 5.249903384308326, "Anaphylactic shock ": 5.335533042116636, "Blood pressure increased ": 2.3280484829120605, "Bone pain ": 2.049112437286263, "Cardiac failure ": 4.754201012928661, "Chest discomfort ": 2.7412139608184813, "Death ": 4.665329894546545, "Dehydration ": 2.466418119290907, "Diarrhoea ": 4.829383774564465, "Disease progression ": 6.933375395934014, "Dyspnoea ": 2.214366326172601, "Ejection fraction decreased ": 18.93911789607467, "Febrile neutropenia ": 4.567332124354529, "Flushing ": 6.53996650230572, "Heart rate increased ": 2.0255045571431425, "Hyperpyrexia ": 6.544825074071549, "Hypersensitivity ": 4.506661707713622, "Infusion related reaction ": 22.759051600025884, "Interstitial lung disease ": 2.9442108924753807, "Leukopenia ": 2.3851098462010696, "Metastases to central nervous system ": 10.500135282061494, "Myelosuppression ": 10.975652294960303, "Neuropathy peripheral ": 2.2974886740037377, "Neutropenia ": 3.101452895956794, "Neutrophil count decreased ": 6.887184139759491, "Oxygen saturation decreased ": 8.046205184682673, "Respiratory distress ": 2.9171843994845124, "Tachycardia ": 2.4274643492201573, "White blood cell count decreased ": 5.92307378257393}
\ No newline at end of file
+{"Alanine aminotransferase increased": 6.005476762618425, "Alveolar soft part sarcoma": 2393.722277868474, "Amylase increased": 5.899918398429357, "Ascites": 2.204751588921844, "Aspartate aminotransferase increased": 4.96016328553554, "Blood alkaline phosphatase increased": 2.1979120649952697, "Blood bilirubin increased": 7.800948825404019, "Blood pressure increased": 2.1557596487063453, "Blood pressure systolic increased": 4.562947080318598, "Blood thyroid stimulating hormone increased": 12.126120596847892, "Cardiac failure": 2.169287034389464, "Clear cell renal cell carcinoma": 376.3078547219088, "Decreased appetite": 3.44639056265582, "Diarrhoea": 2.9524831934416453, "Disease progression": 4.687897009170715, "Drug-induced liver injury": 5.510634071975046, "Ewing's sarcoma": 190.91307841316643, "Gastrointestinal toxicity": 14.277915741464014, "Haemoptysis": 2.8429838048179588, "Hair colour changes": 69.88264006999313, "Hepatic failure": 2.9361488499410715, "Hepatic function abnormal": 5.457018408316558, "Hepatotoxicity": 21.881884249347717, "Hyperbilirubinaemia": 8.237906255736153, "Hypertension": 5.495618068362016, "Hypertransaminasaemia": 7.294641958004463, "Hypothyroidism": 7.411496511870068, "Intestinal perforation": 8.819903321288153, "Jaundice": 2.985917401333833, "Leiomyosarcoma": 233.90928402187205, "Liver function test abnormal": 2.583598603221104, "Liver function test increased": 4.620312609536337, "Liver injury": 3.2495188569297917, "Malignant neoplasm progression": 38.95369816501778, "Metastases to bone": 12.616916336947613, "Metastases to central nervous system": 17.219248089598665, "Metastases to liver": 10.105666365323083, "Metastases to lung": 47.94854878515119, "Metastases to lymph nodes": 18.11540227348305, "Metastases to spine": 23.342671409656152, "Metastatic renal cell carcinoma": 52.539787273854216, "Mucosal inflammation": 2.913754855245118, "Neoplasm progression": 2.3883253303420777, "Nephrotic syndrome": 6.527876194109605, "Neutropenia": 2.1400208925224598, "Osteosarcoma metastatic": 862.0287985077421, "Palmar-plantar erythrodysaesthesia syndrome": 16.5570235431447, "Platelet count decreased": 2.5470386332828068, "Pleural effusion": 3.866218788132558, "Pneumothorax": 32.419494668662544, "Posterior reversible encephalopathy syndrome": 12.325488290256157, "Product use in unapproved indication": 8.362406642637614, "Proteinuria": 9.60978881754176, "Pulmonary mass": 4.235672980853655, "Renal cancer": 3.280296527797834, "Renal cell carcinoma": 29.374748934370736, "Soft tissue sarcoma": 266.8290850373411, "Taste disorder": 2.1667296057952354, "Therapeutic response decreased": 6.040715336343409, "Therapy partial responder": 13.153834687498836, "Thrombocytopenia": 2.6393003845493177, "Transaminases increased": 10.600677984415272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/857.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/857.json
index ba9b047fa06..12b5793e65d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/857.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/857.json
@@ -1 +1 @@
-{"Cardiac failure ": 7.725287309307281, "Cardiotoxicity ": 55.73073659640681, "Diarrhoea ": 3.242182744686482, "Disease progression ": 8.543077741966828, "Ejection fraction decreased ": 75.59941775510055, "Febrile neutropenia ": 17.226346395835417, "Flushing ": 4.300065078677275, "Infusion related reaction ": 10.059885656161416, "Left ventricular dysfunction ": 37.70973436625419, "Leukopenia ": 3.2880506145431565, "Metastases to central nervous system ": 16.292755740890993, "Myelosuppression ": 21.30114627392455, "Neuropathy peripheral ": 5.842784754656542, "Neutropenia ": 9.378346503749755, "Neutrophil count decreased ": 10.451775582788557, "Off label use ": 2.626503223305213, "Renal impairment ": 2.857344746851234, "White blood cell count decreased ": 4.636403099802152}
\ No newline at end of file
+{"Abdominal pain": 2.2665945999167167, "Agranulocytosis": 13.683229995519577, "Anaphylactic reaction": 2.8418391651717227, "Antithrombin III decreased": 575.9895961791626, "Coagulopathy": 15.246538514936956, "Embolism venous": 191.89311462798915, "Febrile neutropenia": 15.743999083044455, "Granulocytopenia": 22.927136602743246, "Haemoglobin decreased": 2.150854898690236, "Hepatic function abnormal": 2.9499715632230257, "Hypersensitivity": 3.895219141871332, "Hypertriglyceridaemia": 55.46322503486626, "Infection": 3.015463228536685, "Leukopenia": 3.1749231858676064, "Myelosuppression": 92.99782563488202, "Neutrophil count decreased": 7.549995066028913, "Pancreatitis": 5.48124796280896, "Pancytopenia": 7.840648745542014, "Platelet count decreased": 6.097167600834943, "Thrombocytopenia": 3.039213106346901, "Urticaria": 2.684179929667882, "White blood cell count decreased": 8.112431180730317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/858.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/858.json
index 3dcc84565ef..a87b5109ecd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/858.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/858.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 2.081425096886747, "Cardio-respiratory arrest ": 6.227740874401152, "Completed suicide ": 14.62938634371715, "Drug interaction ": 2.612723980660734, "Hallucination, visual ": 65.54495287783573, "Hepatic enzyme increased ": 2.19872677036686, "Hyperglycaemia ": 2.5777670484436626, "Hyperthyroidism ": 57.903364911478015, "Hypoglycaemia ": 16.123977300365524, "Hypoglycaemic coma ": 27.96394571728185, "Influenza ": 10.12611224470729, "Intentional overdose ": 5.9082427349603925, "Neutropenia ": 7.91768885037507, "Renal impairment ": 2.5590417102822065, "Shock ": 12.637787872803091, "Suspected suicide ": 32.93100537419011, "Toxicity to various agents ": 3.657993130570947, "Type 2 diabetes mellitus ": 80.67181806877197, "Weight increased ": 5.19238448640317, "White blood cell count decreased ": 14.337367824150247, "White blood cell count increased ": 6.863550994172742}
\ No newline at end of file
+{"Abdominal infection": 2.394671059154865, "Abortion spontaneous": 2.114093662417026, "Abscess": 2.8200358057637023, "Abscess limb": 3.1456478539677666, "Acquired haemophilia": 3.138899803904076, "Acute psychosis": 3.270185807663208, "Acute stress disorder": 2.969714753494276, "Affective disorder": 2.073042001878912, "Alanine aminotransferase abnormal": 3.366536908045192, "Alanine aminotransferase increased": 2.4862034969428417, "Alcohol use": 6.55870769963997, "Alcoholism": 2.148644745952752, "Alopecia": 3.020918928808236, "Alopecia totalis": 3.1805242980303534, "Alpha 1 foetoprotein increased": 10.339133414728591, "Ammonia increased": 8.490191464134423, "Anaemia": 10.856081212774754, "Anaemia macrocytic": 4.5229869174040775, "Anal fissure": 2.238158940034937, "Anal haemorrhage": 2.6022841428211843, "Anal inflammation": 4.660851110761988, "Anal pruritus": 28.45281085338077, "Anger": 4.828531391228215, "Angular cheilitis": 6.427978045524723, "Anorectal discomfort": 37.35516016730588, 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3.145081888916673, "Blood test abnormal": 2.8223681388621675, "Blood thyroid stimulating hormone decreased": 4.843458456607736, "Blood thyroid stimulating hormone increased": 3.965919619290296, "Blood triglycerides increased": 2.433619121002644, "Blood uric acid increased": 2.2211819539518656, "Bone marrow disorder": 3.567110032805449, "Bone marrow failure": 2.340701173798871, "Bone marrow oedema": 2.9542107648907314, "Brain abscess": 2.553401724187239, "Brain hypoxia": 2.0026783142203635, "Brain stem haemorrhage": 2.251000747453597, "Carbohydrate antigen 19-9 increased": 4.272514641406242, "Cellulitis": 2.1801629576672634, "Cerebellar haemorrhage": 2.882877143779838, "Chapped lips": 2.70185097197796, "Chorea": 2.4858534341170944, "Chronic hepatic failure": 8.225071437874885, "Chronic hepatitis C": 9.53626242358278, "Clubbing": 5.540838200373807, "Colitis ischaemic": 3.7135905529107336, "Coma hepatic": 2.1299743612146083, "Crying": 2.000921207935645, "Cryoglobulinaemia": 21.537640796997987, "Cutaneous sarcoidosis": 8.232388210848448, "Deafness": 2.204780301795479, "Deafness unilateral": 2.271282694386239, "Decreased appetite": 2.4731041621755363, "Dehydration": 2.9913041143361974, "Demyelinating polyneuropathy": 2.397865990226409, "Dental caries": 2.095454291685986, "Dental restoration failure": 4.119843891416878, "Depression": 6.374490651132759, "Depressive symptom": 2.622464177618415, "Dermal cyst": 2.4183025313187896, "Dermatitis": 2.325876806124491, "Dermatitis infected": 7.027374826211197, "Diabetes mellitus": 2.036904087521839, "Drug specific antibody absent": 2.7744894909161397, "Dry skin": 5.326728429618185, "Dyschezia": 3.7787155897268376, "Dysgeusia": 2.6576526095404804, "Emotional disorder": 2.4549170492396573, "Empyema": 2.555324873058888, "Endocarditis": 3.8035423732818976, "Endocarditis bacterial": 3.966557141860426, "Endodontic procedure": 3.844208586611816, "Eosinophil count decreased": 2.1210880057740438, "Erythema nodosum": 2.434671991097386, "Escherichia sepsis": 2.921100836387362, "Exposure via body fluid": 2.433652797289394, "Exposure via skin contact": 2.6800920082488298, "Failure to thrive": 4.895895703818265, "Fat tissue increased": 2.1568549551210863, "Fibrosis": 2.5639962661187194, "Full blood count abnormal": 2.665764304262987, "Full blood count decreased": 8.724457781966105, "Furuncle": 2.5750134696979226, "Gallbladder polyp": 3.80025163421434, "Gastric pH decreased": 2.872197029649099, "Gingival bleeding": 3.71265382402777, "Gingival pain": 2.3317856275493303, "Granulocyte count decreased": 7.660713173576283, "Granulocytopenia": 5.519188858185659, "Granulomatous liver disease": 4.532703579706318, "Graves' disease": 4.517214762417995, "Gravitational oedema": 2.6643805846401776, "Haemangioma of liver": 3.0180354213133453, "Haematemesis": 2.2337785705808004, "Haematocrit abnormal": 5.25921771551082, "Haematocrit decreased": 6.866375065843592, "Haematology test abnormal": 8.399116914428886, "Haemochromatosis": 8.25056931707855, "Haemoglobin": 20.63941900416405, "Haemoglobin abnormal": 4.651654299375388, "Haemoglobin decreased": 9.655638470666378, "Haemolytic anaemia": 8.697255856136703, "Haemorrhoidal haemorrhage": 2.493162542268886, "Haemorrhoids": 4.931697417775261, "Haemorrhoids thrombosed": 3.2380903027789647, "Hand dermatitis": 2.356356897487794, "Hepatic cancer": 2.730850008307717, "Hepatic cancer recurrent": 8.891482554877246, "Hepatic cirrhosis": 10.55538089373633, "Hepatic encephalopathy": 5.130926981523602, "Hepatic failure": 3.443414651590041, "Hepatic fibrosis": 4.754606118452727, "Hepatic mass": 3.794014914531565, "Hepatic neoplasm": 3.3080952244922788, "Hepatic pain": 8.362370050043396, "Hepatitis B DNA increased": 3.472633003225663, "Hepatitis B surface antigen positive": 13.26700719516867, "Hepatitis C": 10.999716272042145, "Hepatitis C RNA increased": 29.76771912571276, "Hepatitis C RNA positive": 17.49627553969152, "Hepatitis C virus test": 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abnormal": 2.6750691600372205, "Leukopenia": 5.398119339457753, "Limb mass": 2.6378063666562963, "Liver tenderness": 4.323495871313302, "Liver transplant": 2.4687698225527845, "Liver transplant rejection": 3.294369690463115, "Loose tooth": 2.891460078326796, "Lung abscess": 2.005352668416377, "Lymph node tuberculosis": 2.949003532312677, "Lymphocyte count increased": 3.182507242259926, "Macrocytosis": 3.1822239735592426, "Major depression": 2.599668333410378, "Mass": 2.1574938055007142, "Memory impairment": 2.35219547194414, "Meningitis viral": 2.343774189009945, "Mental disorder": 2.5043278693789026, "Mononeuropathy multiplex": 5.523378368757425, "Mood altered": 3.9170019104844354, "Mood swings": 3.773605450971736, "Mouth injury": 2.0821070060505384, "Muscle abscess": 4.729710007216791, "Nasal ulcer": 3.2651175792031752, "Nephrotic syndrome": 2.2435592816047065, "Nervousness": 2.1920055466226738, "Neutropenia": 4.936694813495474, "Neutrophil count abnormal": 5.209846730989928, "Neutrophil count decreased": 8.76777296289789, "No adverse event": 3.959864859315759, "Ocular vascular disorder": 3.534021348166976, "Oesophageal varices haemorrhage": 7.543699955078122, "Optic ischaemic neuropathy": 4.439784482206279, "Optic neuritis": 2.159315863619944, "Optic neuropathy": 2.4748696296274693, "Oral fungal infection": 3.160035187627252, "Oral infection": 3.1820411826383297, "Oral lichen planus": 2.498449708420172, "Oral mucosal blistering": 3.297024115683356, "Osmotic demyelination syndrome": 7.2797245048246015, "Pancytopenia": 5.848013727865227, "Papilloedema": 2.7331147756334957, "Paranoia": 3.679762711832305, "Paternal exposure timing unspecified": 8.31624681105071, "Peripheral motor neuropathy": 2.9221716322032134, "Peripheral sensorimotor neuropathy": 2.0087261054667325, "Peritonitis bacterial": 3.8031219938512897, "Peroneal nerve palsy": 2.3608292066645986, "Pharyngeal disorder": 2.8197355795100525, "Pharyngeal ulceration": 5.874985072507446, "Physical assault": 2.0237567444924363, "Platelet count abnormal": 4.764929184154894, "Platelet count decreased": 9.857234295713363, "Platelet disorder": 4.254657659778611, "Pleurisy": 2.493331852741769, "Pneumococcal sepsis": 3.7472211405682647, "Pneumonia pneumococcal": 2.442649027553118, "Pneumonia staphylococcal": 2.957090187807436, "Pneumonia streptococcal": 7.061844426530764, "Polymyositis": 6.100394054249318, "Porphyria non-acute": 16.16536088612806, "Portal hypertension": 5.313027487976421, "Pregnancy of partner": 12.513707960459236, "Procedural complication": 2.394694919680528, "Proctalgia": 6.765729653415421, "Product counterfeit": 2.4270704554170552, "Prurigo": 3.3932990885150165, "Psoas abscess": 4.096950187522695, "Psoriasis": 2.3397961595430514, "Psychotic disorder": 4.165478632477139, "Pulmonary granuloma": 2.546950649512058, "Pulmonary sarcoidosis": 8.894496582030062, "Pulmonary tuberculosis": 2.913748357730022, "Rash": 2.016778954083918, "Rectal abscess": 5.259920454766123, "Red 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response delayed": 2.0026783142203635, "Therapy non-responder": 3.509193875149839, "Thinking abnormal": 2.238463428566778, "Thrombocytopenia": 4.415598069641131, "Thrombocytopenic purpura": 3.114171628324546, "Thrombotic thrombocytopenic purpura": 3.595159884021149, "Thyroid disorder": 4.371569488329394, "Thyroid function test abnormal": 9.533002508274675, "Thyroid hormones increased": 4.458305022485583, "Thyroiditis": 5.011843303437852, "Thyroiditis acute": 5.4604569705428805, "Thyroxine increased": 3.674212625672781, "Tongue disorder": 2.371113596964113, "Tongue erythema": 2.197327208547188, "Tooth abscess": 2.544499742450005, "Tooth infection": 2.2149747826574537, "Toxic shock syndrome": 5.732189841457928, "Transfusion": 8.967226893388936, "Trisomy 21": 2.6579682507136004, "Tuberculin test positive": 2.172627861645715, "Tuberculosis": 2.311289699114206, "Tuberculous pleurisy": 4.891064107128184, "Tympanic membrane perforation": 2.180159899447024, "Type 1 diabetes mellitus": 5.593327030678427, "Underweight": 2.474092611415737, "Urosepsis": 2.496483875191424, "Varices oesophageal": 13.218864828360244, "Violence-related symptom": 4.367869339207155, "Viral load decreased": 16.132272360540007, "Viral load increased": 22.90058888141333, "Viral test positive": 4.785999630580513, "Virologic failure": 2.1131899223825954, "Vision blurred": 2.05337653587614, "Vogt-Koyanagi-Harada disease": 10.081442698463515, "Weight decreased": 4.122401412320108, "White blood cell count abnormal": 3.66934892534104, "White blood cell count decreased": 14.329082505493377, "White blood cell disorder": 7.37444050070655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/859.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/859.json
index d0a367b5fe3..08816e50e1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/859.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/859.json
@@ -1 +1 @@
-{"Blood glucose increased ": 12.713191127032475, "Breast cancer ": 5.626746484333479, "Breast cancer metastatic ": 43.98467014680431, "Colitis ": 6.025353199249127, "Dehydration ": 2.3588537905735776, "Diabetes mellitus ": 9.45279038400892, "Diabetic ketoacidosis ": 18.280216893171648, "Diarrhoea ": 3.851986577253494, "Disease progression ": 3.2311302779948297, "Hyperglycaemia ": 90.6698687634995, "Hyperglycaemic hyperosmolar nonketotic syndrome ": 217.3686244158599, "Ketoacidosis ": 20.65949515863162, "Malignant neoplasm progression ": 10.087116948684503, "Metastases to liver ": 9.271530529835005, "Mucosal inflammation ": 7.152458026021125, "Off label use ": 2.7299149608412363, "Rash ": 8.382434411308836, "Stomatitis ": 6.4326821372027245, "Weight decreased ": 2.088678424041207}
\ No newline at end of file
+{"Acute kidney injury": 2.2689764200619247, "Agranulocytosis": 2.809958748333007, "Anaemia": 2.814067266152577, "Anaphylactic reaction": 2.145073604527459, "Aortitis": 613.5579472683735, "Arrhythmia": 5.632229392640844, "Blood lactate dehydrogenase increased": 18.46529312678713, "Bone pain": 26.96172059293343, "Bronchitis": 4.748090905453391, "C-reactive protein increased": 10.39945341041051, "Embolism": 21.819417677679464, "Febrile neutropenia": 49.12868073982738, "General physical health deterioration": 7.686962778184768, "Infection": 4.571167718882419, "Leukocytosis": 11.068767733409931, "Leukopenia": 8.334166905565855, "Mucosal inflammation": 13.12904535157648, "Myelosuppression": 2.175068292087747, "Neutropenia": 11.042239648549716, "Neutrophil count decreased": 13.693435977510296, "Pneumonia": 3.004271124115495, "Pulmonary embolism": 3.4296730116728518, "Pulmonary thrombosis": 17.390031690283337, "Sepsis": 5.571065086426875, "Stomatitis": 2.6350230536707504, "Thrombocytopenia": 4.760225532703807, "Urinary tract infection": 4.063659520204881, "Vasculitis": 10.577852194339638, "White blood cell count decreased": 4.027264239750097}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/86.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/86.json
index 96a2a1811a0..e2edc69873b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/86.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/86.json
@@ -1 +1 @@
-{"Toxicity to various agents ": 34.113043035237474}
\ No newline at end of file
+{"Foetal exposure during pregnancy": 6.945300574762279}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/860.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/860.json
index f98f8eea10b..70d9c287220 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/860.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/860.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 2.295053504635189, "Adverse drug reaction ": 21.581837887027127, "Adverse reaction ": 48.55819001664136, "Bronchiectasis ": 21.00905712958486, "Cerebrovascular accident ": 2.394732718545204, "Cough ": 3.541896485043054, "Death ": 3.5399156404638354, "Decreased appetite ": 7.512051753676739, "Drug intolerance ": 2.557877738884144, "Dyspepsia ": 2.375431447975917, "Erythema ": 2.533073561078234, "Forced vital capacity decreased ": 405.76837801449045, "Gastrointestinal disorder ": 3.178118821584988, "Hypoxia ": 4.280869916629347, "Idiopathic pulmonary fibrosis ": 166.8642218539805, "Illness ": 8.242357090670469, "Interstitial lung disease ": 4.001933157703228, "Lower respiratory tract infection ": 7.363690924686139, "Oxygen saturation decreased ": 5.823960767821354, "Photosensitivity reaction ": 81.87302339553328, "Pneumonia ": 2.44732457716062, "Pulmonary function test decreased ": 46.75724283173488, "Rash ": 2.2413771349890736, "Transaminases increased ": 3.3914089065389272, "Weight decreased ": 6.143638566505758}
\ No newline at end of file
+{"Abdominal tenderness": 2.05175768503502, "Adverse event": 2.486045021160743, "Alanine aminotransferase increased": 2.1932950732357, "Alopecia totalis": 24.299120254590505, "Alopecia universalis": 86.02430164649437, "Anaemia": 18.12663363403021, "Anal haemorrhage": 6.423823976199437, "Anal pruritus": 67.68052608117532, "Angiotensin converting enzyme increased": 70.14436932856873, "Anorectal discomfort": 30.33917692142135, "Anorectal disorder": 8.284601741361508, "Aplasia pure red cell": 7.73264308463609, "Aplastic anaemia": 7.197434266897775, "Ascites": 3.7841851538138807, "Autoimmune haemolytic anaemia": 8.787393852965156, "Autoimmune hepatitis": 12.574081858862918, "Autoimmune thyroiditis": 9.667195420543443, "Bilirubin conjugated increased": 4.750818852246233, "Blood bilirubin increased": 2.3208578132636024, "Blood creatinine increased": 2.1289510188418657, "Blood disorder": 9.098414215858968, "Blood urea increased": 2.052053170207212, "Blood uric acid increased": 4.5403269253159015, "Bone marrow failure": 3.902716244180676, "Chronic hepatitis C": 87.96849830878531, "Coeliac disease": 2.0860795364404403, "Colitis ischaemic": 4.380923873031978, "Cryoglobulinaemia": 27.820140695207844, "Cutaneous sarcoidosis": 80.12832841453931, "Cutaneous vasculitis": 2.0604717485991317, "Cytopenia": 4.200669112548444, "Deafness neurosensory": 9.773174139675096, "Decreased appetite": 2.5933161468622856, "Depression": 4.292448384359702, "Dermatitis": 2.563784020374567, "Disease recurrence": 2.278641552618645, "Drug eruption": 4.110204965752982, "Drug reaction with eosinophilia and systemic symptoms": 11.3910755217354, "Dry skin": 4.629284477818826, "Erysipelas": 2.00152995649778, "Erythema multiforme": 3.9199138697663782, "Escherichia infection": 5.899741271473969, "Factor VIII inhibition": 4.734202100470303, "Glomerular filtration rate decreased": 2.972268343849347, "Granuloma": 5.031263637677742, "Graves' disease": 7.60540509998259, "Haemoglobin decreased": 9.07603874253652, "Haemolysis": 2.2511420796755077, "Haemolytic anaemia": 7.266141775465452, "Haemorrhoidal haemorrhage": 7.772747236671253, "Haemorrhoids": 9.805466173611904, "Hepatic cancer": 2.6258783517408126, "Hepatic cirrhosis": 5.24890516232784, "Hepatic encephalopathy": 6.438705734719675, "Hepatic failure": 5.390482336424336, "Hepatic pain": 3.140197980507461, "Hepatitis C": 31.911282572903563, "Hepatitis chronic active": 51.8312100964621, "Hepatocellular carcinoma": 6.808505291656262, "Hepatorenal syndrome": 10.755862477019967, "Hyperbilirubinaemia": 4.504520115829125, "Hyperthyroidism": 5.789749410355004, "Hyperuricaemia": 23.365808676321887, "Hypothyroidism": 2.484518463119456, "Hypovolaemia": 2.757941523948967, "Immune thrombocytopenia": 4.159875894222123, "Injection site necrosis": 6.651264214852836, "Interstitial lung disease": 2.073324629199424, "Irritability": 2.3773343510132965, "Leukopenia": 8.590921105551365, "Liver transplant": 9.091632786840236, "Liver transplant failure": 216.20921605597152, "Liver transplant rejection": 13.699027567553191, "Lung infiltration": 3.349489498541369, "Lymph node tuberculosis": 27.136394997868923, "Lymphadenopathy mediastinal": 5.910927332641744, "Lymphopenia": 3.106132958839261, "Major depression": 2.7815453689361043, "Mental disorder": 3.125436440683549, "Monocyte count increased": 5.066591548712127, "Mood altered": 3.1912271811445683, "Mouth ulceration": 3.348314523951591, "Myasthenia gravis": 2.538010425065013, "Mycobacterium abscessus infection": 39.40274218024246, "Neutropenia": 5.444073517003871, "Neutrophil count decreased": 2.188947101101673, "Oesophageal candidiasis": 3.590199469276407, "Optic ischaemic neuropathy": 6.866297589043155, "Optic neuropathy": 9.950603839118072, "Oral candidiasis": 2.384868751403672, "Oral disorder": 3.681851384405282, "Organising pneumonia": 3.297238594525865, "Pancreatitis acute": 2.693064518090718, "Pancytopenia": 6.1828429366359225, "Papule": 2.158713462508949, "Platelet count decreased": 4.439588413347259, "Porphyria non-acute": 41.67349272695679, "Proctalgia": 13.737783149482118, "Pruritus": 2.5479014539034, "Psoriasis": 2.5079651191003878, "Psychotic disorder": 3.820405327661158, "Pulmonary sarcoidosis": 44.70135045759712, "Pulmonary tuberculosis": 9.361609573384415, "Rales": 2.1896283999018222, "Rash": 3.2934199377744564, "Red blood cell count decreased": 2.1769398448989614, "Red blood cell transfusion": 11.510305786449738, "Renal impairment": 2.4327356714257933, "Retinal exudates": 64.12214875453809, "Retinal haemorrhage": 8.071470233191773, "Retinal ischaemia": 87.61303857610712, "Retinal vein occlusion": 3.3561024058885565, "Retinopathy": 46.848390521921615, "Sarcoidosis": 38.58698353506783, "Sepsis": 2.4544871203342327, "Serum ferritin increased": 4.434013604529469, "Skin hyperpigmentation": 2.8590961768122565, "Skin lesion": 2.376360741241249, "Skin mass": 2.8792148646658746, "Skin plaque": 6.559127872448173, "Skin reaction": 2.527961094190675, "Skin ulcer": 2.9075215145798965, "Spontaneous bacterial peritonitis": 21.26076367312149, "Staphylococcal bacteraemia": 5.882792861410981, "Staphylococcal sepsis": 4.902448837393527, "Stevens-Johnson syndrome": 2.3941538326788865, "Sudden hearing loss": 2.9991412085072646, "Therapy non-responder": 7.351679453579079, "Thrombocytopenia": 6.693512221462413, "Thrombotic thrombocytopenic purpura": 4.45445813904927, "Thyroiditis": 3.3266136747177044, "Toxic skin eruption": 3.906682617415401, "Transaminases increased": 2.1329648312555927, "Transfusion": 10.60633124393717, "Transplant failure": 9.662342030301026, "Transplant rejection": 3.826532961537925, "Treatment failure": 4.141818999594627, "Tuberculosis": 3.5212570658391678, "Type 1 diabetes mellitus": 7.587471402362171, "Urosepsis": 2.5348248441830563, "Viraemia": 12.363230589761692, "Viral load increased": 6.039716537112199, "Virologic failure": 15.943060221728189, "Visual acuity reduced": 2.4734504262372723, "Vogt-Koyanagi-Harada disease": 38.49693201227187, "Weight decreased": 3.0624903048551, "White blood cell count decreased": 3.2334232606248388}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/861.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/861.json
index fc0d2a03e30..59b4d528411 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/861.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/861.json
@@ -1 +1 @@
-{"Abdominal wall haematoma ": 6.28994304063291, "Acquired haemophilia ": 3.172403983703888, "Activated partial thromboplastin time prolonged ": 2.432589292809432, "Acute coronary syndrome ": 3.9878396818999975, "Acute myocardial infarction ": 5.3238830434327, "Agranulocytosis ": 4.914840252785733, "Anaemia ": 6.169419127117733, "Aneurysm ": 2.783163353400479, "Angina pectoris ": 4.223473972436615, "Angina unstable ": 8.81379350964742, "Angiopathy ": 3.764565025197937, "Angioplasty ": 3.645819862662734, "Aortic aneurysm ": 4.924655058951651, "Aortic valve disease ": 3.2401241714763445, "Aplastic anaemia ": 4.213671247983228, "Arterial disorder ": 2.1811583509497425, "Arterial haemorrhage ": 6.355952011316006, "Arterial occlusive disease ": 4.987798560949623, "Arterial restenosis ": 47.25363266924098, "Atrial fibrillation ": 2.1074601914480384, "Barrett's oesophagus ": 5.1052873628851945, "Bladder neoplasm ": 5.681022915342981, "Bleeding time prolonged ": 13.806287259183332, "Blood cholesterol decreased ": 6.074325505852805, "Blood disorder ": 2.44863060689101, "Blood iron decreased ": 2.2096870435447684, "Blood loss anaemia ": 29.43288107468145, "Blood urine present ": 3.772079829271092, "Bloody discharge ": 4.297140245820985, "Brain herniation ": 4.35350699944449, "Brain stem haemorrhage ": 9.950861928007686, "Cardiac fibrillation ": 4.203533454656158, "Cardiac operation ": 2.083659650300775, "Cardiac pacemaker insertion ": 3.981885956921984, "Cardiac ventricular thrombosis ": 2.288216277309869, "Carotid artery occlusion ": 7.949387345977489, "Carotid artery stenosis ": 2.026510596699157, "Catheter site haematoma ": 79.02445855326559, "Catheter site haemorrhage ": 7.309961457209004, "Cerebellar haematoma ": 16.47518721007987, "Cerebellar haemorrhage ": 10.645445404572689, "Cerebral haematoma ": 26.294385903518837, "Cerebral haemorrhage ": 22.115280497227296, "Cerebral infarction ": 3.1488466332521177, "Cerebral mass effect ": 5.778248954039571, "Cerebrovascular accident ": 6.141716358074126, "Cholestatic liver injury ": 2.6432378196066355, "Chronic gastritis ": 4.165668029460797, "Coagulation time prolonged ": 3.3581803388588307, "Coagulopathy ": 5.12737158090706, "Colitis ischaemic ": 2.405394736046309, "Compartment syndrome ": 2.3402767808434057, "Conjunctival haemorrhage ": 8.764617160620695, "Contusion ": 4.908728369407085, "Coronary arterial stent insertion ": 7.942217765510513, "Coronary artery disease ": 2.4728509277392035, "Coronary artery occlusion ": 23.35166740383886, "Coronary artery restenosis ": 33.19882751125416, "Coronary artery stenosis ": 6.49371448584202, "Coronary artery thrombosis ": 13.131033253766349, "Decubitus ulcer ": 2.066303273499224, "Deformity ": 3.644726580040652, "Dermatitis exfoliative ": 2.6214398934785423, "Dermatitis exfoliative generalised ": 3.0306962728208697, "Device occlusion ": 12.190020800317544, "Dieulafoy's vascular malformation ": 28.778328679139065, "Discoloured vomit ": 6.5218593584853695, "Diverticulitis intestinal haemorrhagic ": 29.5160022152292, "Diverticulum ": 2.6408760654630403, "Diverticulum intestinal haemorrhagic ": 31.835245275498075, "Drug interaction ": 2.7165233277278413, "Duodenal ulcer ": 12.413672636828542, "Duodenal ulcer haemorrhage ": 28.28715668362136, "Duodenitis ": 5.498682416117826, "Dysgraphia ": 2.432414536987068, "Ear haemorrhage ": 9.300917612588314, "Ecchymosis ": 8.819045324516733, "Embolic stroke ": 4.020423737633144, "Enterocolitis haemorrhagic ": 2.533554145891677, "Eosinophilic pneumonia ": 2.7188848092557523, "Epistaxis ": 10.48132167463632, "Erosive duodenitis ": 14.104380110500095, "Erosive oesophagitis ": 4.324117920289487, "Erythema multiforme ": 2.1051280324286297, "Extradural haematoma ": 14.325601460742062, "Eye haemorrhage ": 9.721068054294289, "Faeces discoloured ": 10.375083645609507, "Gastric haemorrhage ": 22.330132128091737, "Gastric mucosal lesion ": 5.215361841865585, "Gastric ulcer ": 12.071694248665333, "Gastric ulcer haemorrhage ": 34.883538878970114, "Gastric ulcer perforation ": 4.852684293276983, "Gastritis ": 3.897352625413544, "Gastritis erosive ": 12.56743173742952, "Gastritis haemorrhagic ": 16.090567457107856, "Gastrointestinal haemorrhage ": 58.14072678754583, "Gastrointestinal polyp haemorrhage ": 18.225551095337597, "Gastrointestinal ulcer ": 10.108990527443789, "Gastrointestinal ulcer haemorrhage ": 29.122399363631228, "Gastrointestinal vascular malformation haemorrhagic ": 63.69759577999172, "Gingival bleeding ": 8.888100807556258, "Granulocytopenia ": 4.277655841332218, "Haemarthrosis ": 3.708443549757176, "Haematemesis ": 17.439718897034922, "Haematochezia ": 7.555389457139873, "Haematocrit decreased ": 3.330966251613269, "Haematoma ": 8.820475291757107, "Haematoma muscle ": 9.283363490721277, "Haematuria ": 12.126307237353275, "Haemobilia ": 8.634130011881549, "Haemoglobin decreased ": 4.203883964242581, "Haemoperitoneum ": 6.824813963704834, "Haemoptysis ": 8.711071841550929, "Haemorrhage ": 15.74756841204318, "Haemorrhage intracranial ": 13.366081867265708, "Haemorrhage subcutaneous ": 31.575018865403024, "Haemorrhage urinary tract ": 12.316908246133815, "Haemorrhagic arteriovenous malformation ": 159.1499442552488, "Haemorrhagic cerebral infarction ": 9.178141916272528, "Haemorrhagic diathesis ": 11.20542355451585, "Haemorrhagic erosive gastritis ": 17.458051117642274, "Haemorrhagic stroke ": 29.191157039294648, "Haemorrhagic transformation stroke ": 21.71508144073877, "Haemorrhoidal haemorrhage ": 12.933937152801573, "Haemothorax ": 8.13287277779388, "Head injury ": 2.0672421933858205, "Hemiparesis ": 2.916338004213289, "Hemiplegia ": 5.544016957274099, "Hepatic function abnormal ": 2.2849152445377507, "Hepatitis fulminant ": 2.5274009662209256, "Hepatocellular injury ": 2.4162069549370897, "Hernia repair ": 2.7759190970341665, "Hiatus hernia ": 2.2823871712581205, "Hypochromic anaemia ": 4.375159934178359, "Hypovolaemic shock ": 5.373140518859981, "Implant site fibrosis ": 66.67846209606256, "Incision site haemorrhage ": 11.315875907389444, "Increased tendency to bruise ": 6.002860946020523, "Injury ": 3.6589711094991326, "Internal haemorrhage ": 22.00420456040948, "International normalised ratio abnormal ": 2.389411160153802, "International normalised ratio decreased ": 2.622995884057844, "International normalised ratio fluctuation ": 3.312278737729205, "International normalised ratio increased ": 3.953282338771351, "Interstitial lung disease ": 2.006127152272874, "Intestinal haemorrhage ": 8.89784697878515, "Intra-abdominal haematoma ": 9.32629301844029, "Intra-abdominal haemorrhage ": 8.211581888668155, "Intracranial aneurysm ": 4.169441733018772, "Intracranial haematoma ": 19.375652686918187, "Intraventricular haemorrhage ": 12.696408752265803, "Iron deficiency anaemia ": 6.184302645079456, "Ischaemic stroke ": 5.542897982559905, "Jaundice ": 2.095808299797725, "Labelled drug-drug interaction issue ": 12.721136889703276, "Labelled drug-drug interaction medication error ": 21.651846697026063, "Large intestinal haemorrhage ": 15.846210390817337, "Large intestinal ulcer ": 2.461264012467892, "Lip erosion ": 3.278526683660457, "Loss of employment ": 9.382258376442618, "Lower gastrointestinal haemorrhage ": 33.28197483813736, "Mallory-Weiss syndrome ": 10.190047385489, "Melaena ": 28.27726551692328, "Meningorrhagia ": 20.7498074890058, "Microcytic anaemia ": 7.310789076838037, "Mouth haemorrhage ": 8.651168684259495, "Mucosal haemorrhage ": 3.659441874727186, "Multiple injuries ": 352.4772273286153, "Muscle haemorrhage ": 9.421461851994469, "Myocardial infarction ": 5.375368047075587, "Non-cardiac chest pain ": 2.1682345078921483, "Normochromic normocytic anaemia ": 2.1963222721546933, "Normocytic anaemia ": 4.639052070488683, "Occult blood positive ": 23.09045927506125, "Oesophageal disorder ": 2.7366045691650527, "Oesophageal haemorrhage ": 19.13280329807113, "Oesophageal ulcer ": 7.309920750555538, "Oesophageal ulcer haemorrhage ": 19.72427474693973, "Oesophagitis ": 3.2582806962705613, "Oesophagitis ulcerative ": 16.360918015580044, "Pelvic haematoma ": 9.703096181327036, "Peptic ulcer ": 4.693988125896942, "Peptic ulcer haemorrhage ": 27.74344239253145, "Pericardial haemorrhage ": 14.51154824823795, "Periorbital haematoma ": 11.850185208903696, "Peripheral arterial occlusive disease ": 4.547100305217328, "Peripheral artery occlusion ": 6.299287492240356, "Petechiae ": 2.707744136286437, "Pharyngeal haemorrhage ": 4.91471827264757, "Pharyngeal ulceration ": 5.654245672630367, "Physical disability ": 8.682241137144018, "Platelet function test abnormal ": 51.65079099407865, "Polyp ": 2.2464824514100585, "Poor peripheral circulation ": 2.338066155825059, "Post procedural haematoma ": 15.375998685287408, "Post procedural haemorrhage ": 22.005186251289697, "Potentiating drug interaction ": 2.329421002551059, "Prescribed overdose ": 4.576202617219796, "Procedural haemorrhage ": 9.988297316909538, "Product counterfeit ": 24.487052627680413, "Prothrombin level decreased ": 2.0910749344927826, "Prothrombin time prolonged ": 3.488216579291176, "Psychological trauma ": 36.87053850096279, "Pulmonary alveolar haemorrhage ": 3.4027531918162035, "Pulmonary haemorrhage ": 5.6282966646416615, "Puncture site haemorrhage ": 10.865019481166508, "Purpura ": 4.32140517014488, "Putamen haemorrhage ": 9.19892587962771, "Rebound effect ": 2.2488448511020303, "Rectal haemorrhage ": 20.238873400085225, "Renal artery stenosis ": 4.385696259218197, "Renal haematoma ": 13.70401063190136, "Renal haemorrhage ": 8.94223423357372, "Respiratory tract haemorrhage ": 11.714670556254262, "Retinal haemorrhage ": 8.532573482211335, "Retroperitoneal haematoma ": 11.33185287564944, "Retroperitoneal haemorrhage ": 16.624812849855513, "Serum sickness ": 2.773883560134318, "Shock haemorrhagic ": 19.310729220045054, "Skin haemorrhage ": 5.331956820961318, "Small intestinal haemorrhage ": 11.541507891939714, "Social problem ": 5.501297041371289, "Spinal cord haematoma ": 11.912684503082938, "Spinal epidural haematoma ": 4.902329017024855, "Splenic haemorrhage ": 15.067286629194433, "Spontaneous haematoma ": 5.386888734547451, "Stent malfunction ": 29.02105724509085, "Stent placement ": 12.499347093002909, "Subarachnoid haemorrhage ": 12.19462490815097, "Subcutaneous haematoma ": 10.83445632794738, "Subdural haematoma ": 30.88754166314978, "Subdural haemorrhage ": 15.223391912779832, "Suspected counterfeit product ": 5.929053760194957, "Tension ": 3.7976619066512503, "Thalamus haemorrhage ": 11.22157820880138, "Thrombocytopenia ": 2.8054441316982617, "Thrombocytopenic purpura ": 11.594030724354718, "Thrombosis ": 2.866722261456152, "Thrombosis in device ": 35.79999473605581, "Thrombotic thrombocytopenic purpura ": 68.76039314357067, "Tongue haemorrhage ": 7.997916733861288, "Toxic skin eruption ": 2.7612730998833723, "Transient ischaemic attack ": 6.969541862351431, "Traumatic haematoma ": 20.201368983726788, "Traumatic haemorrhage ": 10.825895147601576, "Traumatic intracranial haemorrhage ": 25.100812869438226, "Tumour haemorrhage ": 2.688830446313793, "Ulcer ": 4.05031424190119, "Ulcer haemorrhage ": 231.8802514471334, "Upper gastrointestinal haemorrhage ": 34.89233105922272, "Urethral haemorrhage ": 9.160502241040277, "Urinary bladder haemorrhage ": 14.492368530081992, "Uterine haemorrhage ": 2.460827862492041, "Vascular graft ": 6.808008210158391, "Vascular occlusion ": 17.49389637437199, "Vascular pseudoaneurysm ": 20.764356914504603, "Vascular stent occlusion ": 54.43452760316192, "Vascular stent stenosis ": 29.256617857753945, "Vascular stent thrombosis ": 34.474044570863825, "Vessel puncture site haematoma ": 20.92612543442221, "Vessel puncture site haemorrhage ": 16.52545001629515, "Vitreous haemorrhage ": 4.550340032601111, "Wound haemorrhage ": 11.01750496261446}
\ No newline at end of file
+{"Abnormal sensation in eye": 2.084322590103024, "Abortion induced": 7.867377124620278, "Abortion spontaneous": 2.320057112257917, "Abscess": 3.824662725041792, "Acute psychosis": 5.606059565663121, "Acute respiratory distress syndrome": 3.177103189258625, "Adverse event": 2.0007126100283528, "Affect lability": 2.0667101406331296, "Aggression": 3.2070435027517714, "Alcohol abuse": 2.522592023484853, "Alcoholism": 10.367670195178016, "Alopecia": 2.475212123268486, "Alopecia universalis": 9.122425473278778, "Alveolitis": 4.49384184019817, "Ammonia increased": 3.3838107428023614, "Amnesia": 2.071123063389523, "Anaemia": 9.990574269084108, "Anaemia macrocytic": 2.887803207817908, "Anal pruritus": 3.9272887637429887, "Anger": 3.96912224177088, "Anorectal discomfort": 3.7577784435142942, "Anti-neutrophil cytoplasmic antibody positive vasculitis": 4.091608767835779, "Anti-thyroid antibody positive": 7.516104243376881, "Aplasia pure red cell": 6.453376607821674, "Appendicitis": 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"Cerebellar infarction": 4.459796079300907, "Cerebral haemorrhage": 2.540970976298055, "Cerebral infarction": 2.8655319410860622, "Chapped lips": 2.800322583820305, "Cholecystectomy": 2.655286764176956, "Chronic inflammatory demyelinating polyradiculoneuropathy": 4.511070856971684, "Colitis ischaemic": 11.214496666626587, "Connective tissue disorder": 11.53237051439903, "Coombs positive haemolytic anaemia": 11.21888842208301, "Cryoglobulinaemia": 28.02724341520697, "Cutaneous sarcoidosis": 8.350869435698465, "Deafness": 2.2004023581835623, "Deafness neurosensory": 2.7178549290624803, "Decreased appetite": 3.267888791735825, "Decreased immune responsiveness": 3.022503091221117, "Dehydration": 3.429073841713957, "Delusion": 2.635276954199362, "Depression": 4.686396471036185, "Depressive symptom": 18.02828028460847, "Diabetes mellitus": 4.677338784516457, "Diabetic ketosis": 6.195044171748146, "Disseminated intravascular coagulation": 2.8599875684713667, "Drug eruption": 4.672010911985311, "Drug exposure before pregnancy": 8.69825360655664, "Dry mouth": 2.065606381219386, "Dry skin": 3.585168494221376, "Dysgeusia": 4.881739417072375, "Eczema asteatotic": 8.603176086683266, "Encephalopathy": 2.280285349255256, "Enteritis infectious": 8.562411264644265, "Enterocolitis haemorrhagic": 2.1140361391768483, "Erythema multiforme": 3.441690826109807, "Escherichia sepsis": 2.268377086942889, "Exposure via body fluid": 27.624750342598524, "Facial paralysis": 2.5092059960530646, "Feeding disorder": 2.0230253038636388, "Fluid intake reduced": 2.172692381010178, "Fluid replacement": 15.2184793924201, "Gastrointestinal infection": 3.210533593246148, "Gingival bleeding": 3.036156598972957, "Goitre": 3.4144234193954053, "Granulocytopenia": 2.41502957317963, "Graves' disease": 12.593643762371324, "Haematocrit decreased": 2.933802179443729, "Haemoglobin abnormal": 2.26491664928827, "Haemoglobin decreased": 7.68179900267006, "Haemolysis": 2.482441073657569, "Haemolytic anaemia": 7.391910526407071, "Haemorrhagic cerebral infarction": 6.815147075760715, "Haemorrhoidal haemorrhage": 2.5254171607097837, "Hair texture abnormal": 2.5563502465571144, "Hepatic artery stenosis": 65.52921356671662, "Hepatic cancer": 2.160604981712785, "Hepatic cirrhosis": 6.160783178397923, "Hepatic encephalopathy": 6.377218557353179, "Hepatic failure": 2.241652016966446, "Hepatic fibrosis": 3.994828936692246, "Hepatic mass": 3.5459208449778123, "Hepatic neoplasm": 3.539833829639244, "Hepatic pain": 4.081818816527785, "Hepatitis C": 5.7032020278508, "Hepatitis C RNA increased": 18.03834365547028, "Hepatocellular carcinoma": 2.463860480363384, "Hepatorenal syndrome": 5.677108487319266, "Homicidal ideation": 16.966296080411045, "Homicide": 10.86144446340948, "Hyaluronic acid increased": 229.9380837770497, "Hypersensitivity pneumonitis": 2.632444135533732, "Hyperthyroidism": 8.830731809385144, "Hyperuricaemia": 24.50673824102144, "Hypoacusis": 3.007403261588615, "Hypoalbuminaemia": 2.078539569897931, "Hypothyroidism": 5.864273946906122, "Immune thrombocytopenia": 2.62063852971095, "Infection reactivation": 14.047558024561583, "Influenza like illness": 2.0285873433263046, "Injection site abscess": 9.707400605901418, "Injection site cellulitis": 13.684776272772432, "Injection site discolouration": 3.286596304190232, "Injection site infection": 6.618334975687935, "Injection site necrosis": 41.4015605968823, "Injection site rash": 5.529265529774063, "Injection site reaction": 2.814292652181166, "Injection site ulcer": 54.40757624041827, "Injection site vesicles": 2.89159128554541, "Insomnia": 2.478233936671585, "Interstitial lung disease": 5.369333950365591, "Intervertebral discitis": 5.502203486851474, "Intracranial aneurysm": 4.749091614008878, "Irritability": 3.650876056663505, "Jaundice": 2.387202274608553, "Lacunar infarction": 2.118287269868794, "Leukopenia": 5.243857941756313, "Lip dry": 2.605827300433849, "Liver transplant": 6.172533444558133, "Liver transplant rejection": 6.073202179948938, "Lung infiltration": 3.834235648844026, "Lymph node tuberculosis": 6.254891066078447, "Lymphatic disorder": 15.5253665329719, "Lymphoma": 3.008843057415183, "Mallory-Weiss syndrome": 5.054866311248769, "Malnutrition": 2.100944198813491, "Mania": 2.4160397795734907, "Mean cell volume increased": 5.502575046946735, "Memory impairment": 2.933787384267375, "Meningitis bacterial": 3.074499234801986, "Mental disorder": 3.084396250006178, "Mental status changes": 3.210409064732784, "Mononeuropathy multiplex": 13.961157350823347, "Mood altered": 2.5368567787863925, "Mood swings": 3.3228463373999326, "Muscle abscess": 8.03650631955333, "Muscle atrophy": 2.279827764167504, "Musculoskeletal disorder": 3.585454259027174, "Necrotising fasciitis": 3.515391834048868, "Nervousness": 2.281610054257478, "Neurosis": 11.744435572666768, "Neutropenia": 2.937318239700112, "Neutrophil count decreased": 3.182234615391523, "Non-cardiac chest 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abscess": 8.689713970945844, "Psychiatric symptom": 3.281670866273176, "Psychotic disorder": 4.740014972610066, "Pulmonary sarcoidosis": 8.498278330957756, "Pulmonary tuberculosis": 3.2402997459025897, "Pyelonephritis": 2.421579526196039, "Raynaud's phenomenon": 2.2664341551497014, "Red blood cell count decreased": 7.588078949916194, "Red blood cell transfusion": 4.520038591047882, "Retinal artery occlusion": 5.978729605743709, "Retinal artery thrombosis": 16.190850188273497, "Retinal detachment": 3.3842548095876235, "Retinal disorder": 4.0169389983323285, "Retinal exudates": 94.25267125992168, "Retinal haemorrhage": 24.14369905346032, "Retinal ischaemia": 22.977075856824367, "Retinal vascular thrombosis": 5.725431121513322, "Retinal vein occlusion": 11.679088892669055, "Retinal vein thrombosis": 9.97927039068865, "Retinitis": 4.925367400351732, "Retinopathy": 30.705000610015883, "Sarcoidosis": 14.531881927398729, "Sepsis": 2.415427634791253, "Serum ferritin increased": 2.072456724900973, "Sjogren's syndrome": 2.178699722143336, "Skin disorder": 2.459574525065867, "Skin necrosis": 3.44230165991304, "Skin ulcer": 2.3561383943173264, "Splenic infarction": 2.61026036006261, "Spontaneous bacterial peritonitis": 10.715034833200743, "Staphylococcal infection": 2.660549738248412, "Staring": 2.589372448623031, "Streptococcal infection": 2.99569724684197, "Subarachnoid haemorrhage": 3.3067832041759617, "Substance use": 4.424820512520087, "Sudden hearing loss": 5.70686964067958, "Suicidal ideation": 3.1354626028712, "Thalamus haemorrhage": 7.532296595928472, "Therapeutic product ineffective": 7.002435721320284, "Thirst": 2.452659173528025, "Thrombocytopenia": 2.596900352935488, "Thrombotic thrombocytopenic purpura": 4.25788171645187, "Thyroid disorder": 3.411711297197196, "Thyroid function test abnormal": 3.3548828495788072, "Thyroiditis": 6.9752149101148815, "Tongue disorder": 2.5842445354635366, "Tongue ulceration": 3.4065075693555658, "Tooth abscess": 2.4929345199523385, "Toxic skin eruption": 2.357253317035293, "Transfusion": 20.685621712119307, "Tuberculosis": 2.0771039166099965, "Tuberculous pleurisy": 10.374034978172435, "Tunnel vision": 3.1594182052319075, "Type 1 diabetes mellitus": 21.897156254167225, "Varices oesophageal": 6.368217206785163, "Vasculitis": 2.1351152580651007, "Violence-related symptom": 3.662840562905101, "Viral load increased": 3.5837865174260566, "Visual acuity reduced": 2.2511329986056112, "Visual field defect": 5.325001982935796, "Vogt-Koyanagi-Harada disease": 25.70195007680612, "Weight decreased": 4.432535373979823, "White blood cell count abnormal": 3.894777321082533, "White blood cell count decreased": 5.453411006971207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/862.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/862.json
index fbbce162647..df850c0e3a1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/862.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/862.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.48365168228427, "Accidental underdose ": 26.6908208958039, "Balance disorder ": 2.19049891646544, "Blindness unilateral ": 2.495659992284561, "Blood test abnormal ": 8.553530656642462, "Breast cancer female ": 8.178714821144325, "Caesarean section ": 5.184458923944389, "Central nervous system lesion ": 9.487092350419394, "Cognitive disorder ": 2.0457135058983487, "Coronavirus infection ": 13.071021852545682, "Decreased immune responsiveness ": 3.8727425878296766, "Depressed mood ": 3.595955988914513, "Depression ": 2.042579728845687, "Device malfunction ": 3.2279968254669265, "Drug delivery system malfunction ": 608.044630785028, "Drug dose omission by device ": 80.633419184464, "Drug intolerance ": 2.039858693792359, "Full blood count abnormal ": 4.917956368957904, "Gait disturbance ": 2.076914138201289, "Gamma-glutamyltransferase increased ": 2.387394514153906, "Incorrect dose administered by device ": 11.84875348819214, "Influenza ": 3.0891113886516446, "Influenza like illness ": 18.240420256610207, "Injection site bruising ": 26.013201988495783, "Injection site discolouration ": 46.16490830184277, "Injection site erythema ": 21.834867401333877, "Injection site extravasation ": 6.403381144453388, "Injection site haematoma ": 4.671569357451118, "Injection site haemorrhage ": 62.8847273180763, "Injection site induration ": 7.866865045266279, "Injection site injury ": 53.63190773408921, "Injection site irritation ": 25.9610552877054, "Injection site mass ": 3.726454143235781, "Injection site necrosis ": 8.09404981101053, "Injection site oedema ": 5.2417536033569805, "Injection site pain ": 2.637598636364408, "Injection site pruritus ": 11.843297362292672, "Injection site rash ": 35.06176745408162, "Injection site reaction ": 16.94808451489503, "Injection site urticaria ": 11.932806139661595, "Injection site warmth ": 2.4432155385051733, "Injury associated with device ": 55.45000510044364, "Lack of injection site rotation ": 49.56307188959267, "Leukopenia ": 4.76915987358359, "Listless ": 3.350489073691868, "Liver function test increased ": 9.298335340278353, "Loss of control of legs ": 17.12226485150154, "Lymphocyte count decreased ": 8.930617986823266, "Lymphopenia ": 11.701693174862449, "Magnetic resonance imaging abnormal ": 23.671488700767597, "Maternal exposure during pregnancy ": 2.785077754649936, "Memory impairment ": 2.0043152743431447, "Mobility decreased ": 2.696607554787472, "Motor dysfunction ": 6.750803214393726, "Multiple sclerosis ": 42.094731173501, "Multiple sclerosis relapse ": 67.31078049233504, "Muscle spasticity ": 4.966675769493454, "Musculoskeletal disorder ": 9.79984424322577, "Nasopharyngitis ": 2.9882076993329565, "Optic neuritis ": 5.270160415198022, "Prescribed underdose ": 2.395254961160316, "Product administered at inappropriate site ": 6.107209423305534, "Product dose omission in error ": 6.086868225802203, "Product dose omission issue ": 9.975395658408862, "SARS-CoV-2 test positive ": 2.346664966158821, "Secondary progressive multiple sclerosis ": 63.022141084009775, "Skin reaction ": 5.581177612498316, "Stress ": 3.996781270177048, "Urosepsis ": 3.761959657749801, "White blood cell count abnormal ": 6.085504510925958}
\ No newline at end of file
+{"Drug ineffective": 5.419598637323484, "Neutropenia": 15.796345353246387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/863.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/863.json
index 1dfee7bde09..a17f1c4e329 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/863.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/863.json
@@ -1 +1 @@
-{"Anaemia ": 6.154551369580945, "Disease progression ": 11.69657544309274, "Dry mouth ": 5.745062973842336, "General physical health deterioration ": 35.30781526467567, "Haemoglobin decreased ": 5.849302182717402, "Hormone-refractory prostate cancer ": 628.3275672818521, "Ill-defined disorder ": 167.9114742317682, "Laboratory test abnormal ": 34.39272569593107, "Malignant neoplasm progression ": 16.76075496028068, "Metastases to bone ": 24.338396053255607, "Neoplasm malignant ": 6.092625850982343, "Pancytopenia ": 10.108843906607506, "Platelet count decreased ": 3.9813956249594415, "Prostate cancer ": 33.937123438531856, "Prostate cancer metastatic ": 206.69547058818415, "Prostatic specific antigen increased ": 100.62671114972268, "Thrombocytopenia ": 7.098272864295356}
\ No newline at end of file
+{"Accident": 2.4722783194442024, "Acute kidney injury": 2.4663961500023026, "Adenocarcinoma": 13.404970129232462, "Adrenal insufficiency": 12.208079834863709, "Adrenocorticotropic hormone deficiency": 26.996241241787075, "Adverse event": 3.386883259911374, "Anaemia": 2.2393685052237435, "Atelectasis": 2.2283607107322103, "Atrioventricular block complete": 3.719051999336321, "Autoimmune colitis": 49.979273710275706, "Autoimmune haemolytic anaemia": 11.952697636026326, "Autoimmune hepatitis": 14.372157104986156, "Autoimmune hypothyroidism": 86.86038597547537, "Autoimmune nephritis": 77.25340791481104, "Autoimmune thyroiditis": 11.735728824410394, "Blood thyroid stimulating hormone increased": 5.544790770129857, "Bronchiectasis": 2.298775061160313, "Cachexia": 4.193280860097438, "Cardiac tamponade": 4.039601876622272, "Central nervous system lesion": 5.045058277188986, "Cholangitis": 3.661292524588848, "Cholangitis sclerosing": 16.055249456052806, "Cholecystitis": 2.175927106380916, "Colitis": 13.474927436668647, "Colitis microscopic": 4.974370275844997, "Conjunctivitis": 2.27775391484738, "Cortisol decreased": 11.872056966218144, "Cytokine release syndrome": 3.1609458975146016, "Cytopenia": 2.7189619777506304, "Dermatitis": 3.5903019365419584, "Dermatitis bullous": 3.483598648842467, "Diabetic ketoacidosis": 5.312034656407763, "Drug effective for unapproved indication": 15.53391670002147, "Drug-induced liver injury": 3.3280057510779453, "Eastern Cooperative Oncology Group performance status worsened": 23.19249218843331, "Emphysema": 2.354118053353282, "Encephalitis": 5.745263753749124, "Encephalitis autoimmune": 24.49146152563375, "Enterocolitis": 3.135333840619102, "Eosinophilic fasciitis": 70.55753608928401, "Eyelid ptosis": 4.886720248597092, "Febrile neutropenia": 3.438665614813203, "Fulminant type 1 diabetes mellitus": 35.50204880131232, "Gastritis": 2.2074963936590506, "Gastrointestinal toxicity": 4.178889296420048, "General physical health deterioration": 2.876584457726812, "Groin pain": 2.294421122722232, "Guillain-Barre syndrome": 3.498801080312312, "Haematotoxicity": 4.317281802221969, "Haemophagocytic lymphohistiocytosis": 5.397031303734889, "Hepatitis": 7.479053367345931, "Hepatitis toxic": 3.760940600477056, "Hepatotoxicity": 6.908549875594698, "Hydronephrosis": 3.826931012806324, "Hyperthyroidism": 7.739652271170485, "Hypertransaminasaemia": 9.422480830953967, "Hypophysitis": 41.52946791044046, "Hypopituitarism": 11.89062836850796, "Hypothyroidism": 16.803681739659414, "Immune thrombocytopenia": 3.804638369177528, "Immune-mediated adrenal insufficiency": 12.180790553386824, "Immune-mediated adverse reaction": 218.3609962337172, "Immune-mediated arthritis": 225.40112169505903, "Immune-mediated dermatitis": 110.28158389102845, "Immune-mediated encephalitis": 88.12473905802388, "Immune-mediated enterocolitis": 87.01238917414331, "Immune-mediated gastritis": 138.7524362437781, "Immune-mediated hepatic disorder": 17.701328577193927, "Immune-mediated hepatitis": 159.58314858683067, "Immune-mediated hyperthyroidism": 79.04636038738231, "Immune-mediated hypophysitis": 68.77202184071163, "Immune-mediated hypothyroidism": 108.50116229004126, "Immune-mediated lung disease": 252.2892549395408, "Immune-mediated myasthenia gravis": 142.77021930411232, "Immune-mediated myocarditis": 222.94764746283224, "Immune-mediated myositis": 163.01045574735727, "Immune-mediated nephritis": 97.78667643242784, "Immune-mediated neuropathy": 76.48327868180448, "Immune-mediated pancreatitis": 106.9043138221212, "Immune-mediated renal disorder": 41.02675963556282, "Immune-mediated thyroiditis": 272.9166595203233, "Immune-mediated uveitis": 87.2453277067317, "Inappropriate schedule of product administration": 4.670403836466642, "Interstitial lung disease": 3.3046686483804706, "Intestinal perforation": 2.3067639838674494, "Lichen planus": 8.727841268758885, "Lichenoid keratosis": 15.454466373047763, "Lung adenocarcinoma": 8.449394920990414, 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\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/864.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/864.json
index 9abf72963f4..a13f9724000 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/864.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/864.json
@@ -1 +1 @@
-{"Diffuse large B-cell lymphoma ": 173.55008313044877, "Disease progression ": 51.12181642365399, "Drug ineffective ": 2.100182421197064, "Febrile neutropenia ": 12.957173569799156, "Off label use ": 2.5064058283400508, "Thrombocytopenia ": 3.879896552742375}
\ No newline at end of file
+{"Acute kidney injury": 2.4589991346483107, "Adenocarcinoma": 29.411759205478, "Anaemia": 8.254263839702183, "Blood creatinine increased": 2.65723815982791, "Bone marrow failure": 3.5571300506083587, "Cytopenia": 8.654681846266586, "Decreased appetite": 2.059712047921197, "Disease progression": 8.779625294981704, "Erysipelas": 8.459825764561852, "Eyelid oedema": 5.943825526776097, "Febrile bone marrow aplasia": 26.772052895399803, "Febrile neutropenia": 9.213016454774568, "Fluid retention": 2.3767697755699704, "Gastrointestinal toxicity": 15.46480298601168, "General physical health deterioration": 2.038273245465963, "Glomerular filtration rate decreased": 2.3813590387932786, "Haematotoxicity": 59.72475605556156, "Haemoglobin decreased": 2.1430363265182244, "Haemoptysis": 4.260469760728439, "Hepatic function abnormal": 4.0343043886864685, "Hepatotoxicity": 8.437011960379898, "Hypercreatininaemia": 55.48299098868674, "Hypertransaminasaemia": 6.8597886032104185, "Interstitial lung disease": 3.037791356837816, "Kidney fibrosis": 29.308097536992346, "Lacrimation increased": 2.560465838973916, "Leukopenia": 7.475849312755984, "Liver injury": 2.278333507171818, "Lung adenocarcinoma": 86.98840776426681, "Lung adenocarcinoma stage IV": 142.9284234042745, "Malignant neoplasm progression": 20.37061834568109, "Metastases to bone": 3.4453514551195266, "Metastases to central nervous system": 6.874710134936829, "Metastases to liver": 2.6483612872406144, "Metastases to lung": 3.569441367978779, "Mouth ulceration": 2.584181272144885, "Mucosal inflammation": 7.7321859486767535, "Myelosuppression": 44.96270929325553, "Neoplasm progression": 5.898010270704583, "Nephropathy toxic": 17.20789078806694, "Neutropenia": 10.08471533606842, "Neutropenic colitis": 26.199465956507265, "Neutropenic sepsis": 15.810092617644823, "Neutrophil count decreased": 10.364620404842864, "Non-small cell lung cancer": 29.84811142501192, "Oedema peripheral": 2.014762607666041, "Off label use": 2.154178316510956, "Osteonecrosis of jaw": 4.687289583030724, "Ototoxicity": 31.348768565678352, "Pancytopenia": 10.621235728969689, "Peripheral ischaemia": 11.482248470918138, "Platelet count decreased": 6.5236565887887, "Pleural effusion": 2.607740227700837, "Pneumonia": 2.149662413314887, "Pneumonitis": 7.623794091325042, "Pneumothorax": 2.871185898940192, "Proteinuria": 2.8281726182896776, "Pseudocellulitis": 1527.0649025067391, "Pulmonary toxicity": 7.914760144598592, "Renal impairment": 4.191925576994509, "Renal tubular necrosis": 13.187362614981147, "Respiratory failure": 4.325080090343241, "Scleroderma": 22.765918159140377, "Sepsis": 2.422509859981268, "Skin hyperpigmentation": 7.596153956270079, "Skin toxicity": 16.70435932295389, "Therapeutic response decreased": 2.603158947398427, "Therapy partial responder": 19.845889263031644, "Thrombocytopenia": 6.063438766104069, "Toxic epidermal necrolysis": 3.070247010802734, "Treatment failure": 2.949165635338668, "Tubulointerstitial nephritis": 7.006932152896293, "White blood cell count decreased": 7.598839570149743}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/865.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/865.json
index 30e814d7ceb..691400876ab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/865.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/865.json
@@ -1 +1 @@
-{"Febrile convulsion ": 218.51300411561223, "Pyrexia ": 2.2849047481931057}
\ No newline at end of file
+{"Aggression": 33.183438752010844, "Altered state of consciousness": 12.23001555370216, "Anger": 33.01116502743489, "Balance disorder": 7.2792627732616015, "Drug interaction": 5.968937727079735, "Epilepsy": 15.057648403573708, "Gait disturbance": 3.946716524800802, "Intentional overdose": 9.741663556189955, "Irritability": 17.188830656331135, "Multiple-drug resistance": 151.4527106111148, "Off label use": 2.1422479434716597, "Partial seizures": 45.44369259789571, "Pneumonia aspiration": 20.82629814709234, "Product use in unapproved indication": 3.702758086698696, "Seizure": 5.876503300005169, "Somnolence": 3.5100443356252766, "Suicidal ideation": 4.93186003540748, "Suicide attempt": 8.905146422301383}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/866.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/866.json
index ca069f9721c..a80b5dc7d02 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/866.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/866.json
@@ -1 +1 @@
-{"Disease progression ": 108.19691133660572, "Off label use ": 2.748651637836165}
\ No newline at end of file
+{"Anaphylactic reaction": 5.249791754748052, "Anaphylactic shock": 5.335533042116636, "Blood pressure increased": 2.328007617093588, "Bone pain": 2.049112437286263, "Cardiac failure": 4.753766858863954, "Chest discomfort": 2.7411177314113853, "Death": 4.665329894546545, "Dehydration": 2.466286455489975, "Diarrhoea": 4.829343446645375, "Disease progression": 6.933375395934014, "Dyspnoea": 2.214333420565146, "Ejection fraction decreased": 18.93911789607467, "Febrile neutropenia": 4.567332124354529, "Flushing": 6.53996650230572, "Heart rate increased": 2.0255045571431425, "Hyperpyrexia": 6.544825074071549, "Hypersensitivity": 4.506661707713622, "Infusion related reaction": 22.759051600025884, "Interstitial lung disease": 2.9442108924753807, "Leukopenia": 2.3848091804669624, "Metastases to central nervous system": 10.500135282061494, "Myelosuppression": 10.975652294960303, "Neuropathy peripheral": 2.2974189221912944, "Neutropenia": 3.1013194911639568, "Neutrophil count decreased": 6.887184139759491, "Oxygen saturation decreased": 8.045774316196615, "Respiratory distress": 2.9171843994845124, "Tachycardia": 2.427402989178487, "White blood cell count decreased": 5.92307378257393}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/867.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/867.json
index 5a6f68e9799..015c45af91c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/867.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/867.json
@@ -1 +1 @@
-{"Anaemia ": 4.26577283893718, "Atrial fibrillation ": 3.8203628022725975, "Cardiac failure ": 2.39347336043614, "Cytopenia ": 17.352421602742933, "Death ": 2.189212578989232, "Disease progression ": 5.831834399454936, "Febrile neutropenia ": 10.36837363089763, "General physical health deterioration ": 3.289642555122611, "Infection ": 4.520905249254847, "Lower respiratory tract infection ": 4.200290165033403, "Neuropathy peripheral ": 7.941581610310902, "Neutropenia ": 14.258555903010702, "Neutrophil count decreased ": 5.179085481389913, "Pancytopenia ": 9.382844790844969, "Plasma cell myeloma ": 168.79004554642137, "Plasma cell myeloma recurrent ": 93.22531068431744, "Plasmacytoma ": 119.62528421273352, "Platelet count decreased ": 2.410954945456092, "Pneumonia ": 7.950677044320015, "Pulmonary embolism ": 2.657763824979871, "Renal impairment ": 2.41829284738506, "Sepsis ": 7.631524782308808, "Thrombocytopenia ": 4.690712366417125}
\ No newline at end of file
+{"Cardiac failure": 7.72458187478996, "Cardiotoxicity": 55.73073659640681, "Diarrhoea": 3.242155682494656, "Disease progression": 8.543077741966828, "Ejection fraction decreased": 75.59941775510055, "Febrile neutropenia": 17.226346395835417, "Flushing": 4.300065078677275, "Infusion related reaction": 10.059885656161416, "Left ventricular dysfunction": 37.70973436625419, "Leukopenia": 3.2876361588993137, "Metastases to central nervous system": 16.292755740890993, "Myelosuppression": 21.30114627392455, "Neuropathy peripheral": 5.8426073388920425, "Neutropenia": 9.377942972549832, "Neutrophil count decreased": 10.451775582788557, "Off label use": 2.626399762936207, "Renal impairment": 2.857344746851234, "White blood cell count decreased": 4.636403099802152}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/868.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/868.json
index e71675d05ef..86ccd648e7c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/868.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/868.json
@@ -1 +1 @@
-{"Blood creatinine increased ": 10.010033682439452, "Renal artery angioplasty ": 9805.99548923163, "Renal artery stenosis ": 587.1133236146788, "Renal artery stent placement ": 3435.407529657426}
\ No newline at end of file
+{"Alanine aminotransferase increased": 2.081425096886747, "Cardio-respiratory arrest": 6.227740874401152, "Completed suicide": 14.62938634371715, "Drug interaction": 2.612723980660734, "Hallucination, visual": 65.54495287783573, "Hepatic enzyme increased": 2.19872677036686, "Hyperglycaemia": 2.5777670484436626, "Hyperthyroidism": 57.898074885963794, "Hypoglycaemia": 16.12343243709669, "Hypoglycaemic coma": 27.96394571728185, "Influenza": 10.12611224470729, "Intentional overdose": 5.9082427349603925, "Neutropenia": 7.917348223080974, "Renal impairment": 2.5590417102822065, "Shock": 12.637787872803091, "Suspected suicide": 32.93100537419011, "Toxicity to various agents": 3.657993130570947, "Type 2 diabetes mellitus": 80.67181806877197, "Weight increased": 5.19238448640317, "White blood cell count decreased": 14.337367824150247, "White blood cell count increased": 6.862236654663247}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/869.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/869.json
index d439a2a6912..5ab2fefa8dc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/869.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/869.json
@@ -1 +1 @@
-{"Coma ": 7.324679340334201, "Cyanosis ": 17.362298828950816, "Drug abuse ": 128.15299715990255, "Drug dependence ": 7.356793977485433, "Euphoric mood ": 290.2125957149228, "Feeling abnormal ": 6.677080769786594, "Feeling of relaxation ": 8195.362592278176, "Insomnia ": 3.797002348937057, "Memory impairment ": 22.02625791205271, "Oxygen saturation decreased ": 14.795588577484311, "Poisoning ": 59.76871710773202, "Sleep disorder ": 6.328261912149192, "Substance abuse ": 128.38687960271358, "Tachycardia ": 2.351792581033437, "Toxicity to various agents ": 3.022339210321896, "Vision blurred ": 5.002092310136744, "Withdrawal syndrome ": 18.629403926374323}
\ No newline at end of file
+{"Blood glucose increased": 12.713191127032475, "Breast cancer": 5.626746484333479, "Breast cancer metastatic": 43.98467014680431, "Colitis": 6.025353199249127, "Dehydration": 2.358727889500349, "Diabetes mellitus": 9.45279038400892, "Diabetic ketoacidosis": 18.280216893171648, "Diarrhoea": 3.851954422678523, "Disease progression": 3.2311302779948297, "Hyperglycaemia": 90.6698687634995, "Hyperglycaemic hyperosmolar nonketotic syndrome": 217.3686244158599, "Ketoacidosis": 20.65949515863162, "Malignant neoplasm progression": 10.087116948684503, "Metastases to liver": 9.271530529835005, "Mucosal inflammation": 7.152458026021125, "Off label use": 2.729807424173977, "Rash": 8.382319192393362, "Stomatitis": 6.4326821372027245, "Weight decreased": 2.088678424041207}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/87.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/87.json
index 259ba8e8026..b97c9dba297 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/87.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/87.json
@@ -1 +1 @@
-{"Completed suicide ": 27.09054077122279, "Toxicity to various agents ": 16.618445591439382}
\ No newline at end of file
+{"Abdominal distension": 2.102098540673646, "Abnormal behaviour": 7.656193957164304, "Aggression": 4.091737896443417, "Agitation": 3.16552049140356, "Decreased interest": 41.17722194602349, "Dehydration": 2.3613410225594245, "Drug interaction": 2.8139688350245, "Exposure during pregnancy": 4.752764445805536, "Fear": 8.642087545705975, "Hallucination, auditory": 7.925452504116055, "Hypokalaemia": 2.498696863856688, "Inappropriate affect": 96.89138874033952, "Intentional product misuse": 2.0501502427803837, "Irritability": 2.3181772749494387, "Live birth": 24.482197729375407, "Lung disorder": 5.23722881344897, "Maternal exposure during pregnancy": 3.256675899068878, "Memory impairment": 2.291643309185935, "Mental status changes": 16.5333227963875, "Normal newborn": 32.74166895002574, "Paranoia": 26.71934929252364, "Pneumonia": 2.4517125532394286, "Premature baby": 4.105853583309913, "Respiratory failure": 2.8123856319576745, "Social avoidant behaviour": 29.35255761224113, "Substance abuse": 8.95778877498611, "Substance-induced psychotic disorder": 64.38417378455624, "Urinary tract infection": 4.69448113040033}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/870.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/870.json
index ccc20e101eb..28a712a4f8e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/870.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/870.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.1297187683257275, "Aspergillus infection ": 30.36901757396796, "Blood bilirubin increased ": 2.3390358965387645, "Bronchopulmonary aspergillosis ": 13.653872966793005, "Candida infection ": 13.488552157105609, "Cholestasis ": 5.063814515427367, "Condition aggravated ": 2.6823732668275038, "Disease progression ": 3.227390373072085, "Drug ineffective ": 5.585096023072153, "Drug ineffective for unapproved indication ": 10.785472909912825, "Drug interaction ": 16.904420404916365, "Drug level below therapeutic ": 86.68917342704319, "Drug level decreased ": 18.90997515650169, "Drug level increased ": 10.8114680578307, "Drug resistance ": 9.194598382781573, "Drug-induced liver injury ": 3.070147702706404, "Electrocardiogram QT prolonged ": 3.563099572978805, "Encephalopathy ": 11.507125946877672, "Febrile neutropenia ": 2.3914653118216247, "Fungaemia ": 63.97711774661576, "Fungal infection ": 22.57499820058748, "Graft versus host disease ": 16.864822357495758, "Hallucination, visual ": 5.696964522562297, "Hepatic cytolysis ": 7.092548135780718, "Hepatotoxicity ": 8.128528294553155, "Hyperbilirubinaemia ": 5.946134570743815, "Hypokalaemia ": 5.980548155225688, "Hypomagnesaemia ": 13.744022326403568, "Ileus paralytic ": 19.061689494692185, "Iridocyclitis ": 28.55487422693647, "Mental status changes ": 6.86516154137159, "Mucormycosis ": 71.80780084153649, "Multiple organ dysfunction syndrome ": 4.38267615005681, "Nephropathy toxic ": 7.330339632259821, "Neurotoxicity ": 15.0974259307694, "Neutropenia ": 2.3254239816168405, "Off label use ": 2.182302417898296, "Pancytopenia ": 2.1410013034757966, "Pathogen resistance ": 56.69041788506062, "Pneumonia fungal ": 48.1700031930461, "Posterior reversible encephalopathy syndrome ": 14.205863310938328, "Primary adrenal insufficiency ": 333.4399540432499, "Product use in unapproved indication ": 4.672765841053111, "Product use issue ": 2.611424123893368, "Pseudoaldosteronism ": 792.8375288062289, "Rash maculo-papular ": 6.827515000791375, "Renal disorder ": 3.7159085975667394, "Renal impairment ": 3.117155697899431, "Respiratory failure ": 4.213265130419116, "Rhabdomyolysis ": 4.701720694925154, "Septic shock ": 5.027440280304012, "Sinusitis ": 2.3034153117200864, "Systemic mycosis ": 157.89058464323432, "Torsade de pointes ": 16.209239521131057, "Treatment failure ": 5.610299930096147, "Ventricular tachycardia ": 5.101424818547481}
\ No newline at end of file
+{"Abdominal discomfort": 2.295053504635189, "Adverse drug reaction": 21.581837887027127, "Adverse reaction": 48.55819001664136, "Bronchiectasis": 21.00905712958486, "Cerebrovascular accident": 2.39468956274326, "Cough": 3.5418636257903686, "Death": 3.5399156404638354, "Decreased appetite": 7.511978842072349, "Drug intolerance": 2.557877738884144, "Dyspepsia": 2.375431447975917, "Erythema": 2.5330487823722296, "Forced vital capacity decreased": 405.76837801449045, "Gastrointestinal disorder": 3.1780187483562603, "Hypoxia": 4.280869916629347, "Idiopathic pulmonary fibrosis": 166.8642218539805, "Illness": 8.242357090670469, "Interstitial lung disease": 4.001933157703228, "Lower respiratory tract infection": 7.363690924686139, "Oxygen saturation decreased": 5.823649093624866, "Photosensitivity reaction": 81.87302339553328, "Pneumonia": 2.44732457716062, "Pulmonary function test decreased": 46.75724283173488, "Rash": 2.241346342576612, "Transaminases increased": 3.391201240927147, "Weight decreased": 6.143638566505758}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/871.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/871.json
index 8eed438e741..552f5aac547 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/871.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/871.json
@@ -1 +1 @@
-{"Disease progression ": 26.95664593429937, "Drug eruption ": 46.130976230340174, "Hypercalcaemia ": 18.129281781054377, "Inappropriate schedule of product administration ": 4.570649351721388, "Infusion related reaction ": 31.61374002051957, "Leukopenia ": 2.788030074474355, "Liver disorder ": 4.941759699053839, "Lymphopenia ": 62.31663035119141, "Myocarditis ": 7.022884251373756, "Rash ": 3.850493674785182, "Sepsis ": 6.685246545295988, "Toxic epidermal necrolysis ": 10.77964029755511, "Tumour lysis syndrome ": 30.5488812903053}
\ No newline at end of file
+{"Abdominal wall haematoma": 6.2889205596248825, "Acquired haemophilia": 3.171888303539582, "Activated partial thromboplastin time prolonged": 2.4321938612491, "Acute coronary syndrome": 3.987191417086167, "Acute myocardial infarction": 5.323017518064351, "Agranulocytosis": 4.914041204414626, "Anaemia": 6.168415825046164, "Aneurysm": 2.7827109367542846, "Angina pectoris": 4.222787338313758, "Angina unstable": 8.812360712420924, "Angiopathy": 3.7639530705298143, "Angioplasty": 3.645227226938779, "Aortic aneurysm": 4.923854520126811, "Aortic valve disease": 3.239597482420156, "Aplastic anaemia": 4.21298627601648, "Arterial disorder": 2.180803799566201, "Arterial haemorrhage": 6.354918828203465, "Arterial occlusive disease": 4.986987747410097, "Arterial restenosis": 47.24595151381424, "Atrial fibrillation": 2.1070596004027617, "Barrett's oesophagus": 5.104457474926544, "Bladder neoplasm": 5.680099449167661, "Bleeding time prolonged": 13.804042945464918, "Blood cholesterol decreased": 6.073338111673948, "Blood disorder": 2.4482325684990345, "Blood iron decreased": 2.209327847092413, "Blood loss anaemia": 29.42809605238273, "Blood urine present": 3.771466632492318, "Bloody discharge": 4.296441736643694, "Brain herniation": 4.35279931755304, "Brain stem haemorrhage": 9.94924435921128, "Cardiac fibrillation": 4.202850152388321, "Cardiac operation": 2.0833209409675955, "Cardiac pacemaker insertion": 3.9812386747678095, "Cardiac ventricular thrombosis": 2.287844318343994, "Carotid artery occlusion": 7.948095106370769, "Carotid artery stenosis": 2.026181181131145, "Catheter site haematoma": 79.01161272442363, "Catheter site haemorrhage": 7.308773189681605, "Cerebellar haematoma": 16.472509102429786, "Cerebellar haemorrhage": 10.643714890325509, "Cerebral haematoma": 26.290111189774876, "Cerebral haemorrhage": 22.111684213579125, "Cerebral infarction": 3.148334728900812, "Cerebral mass effect": 5.777309687685687, "Cerebrovascular accident": 6.145603354454316, "Cholestatic liver injury": 2.6428081537453547, "Chronic gastritis": 4.164990879415005, "Coagulation time prolonged": 3.3576344535600677, "Coagulopathy": 5.126538035279253, "Colitis ischaemic": 2.405003724746148, "Compartment syndrome": 2.3398963632604493, "Conjunctival haemorrhage": 8.763192351740049, "Contusion": 4.907930258025183, "Coronary arterial stent insertion": 7.940926705767684, "Coronary artery disease": 2.472448928670812, "Coronary artery occlusion": 23.347870957719294, "Coronary artery restenosis": 33.19343088637776, "Coronary artery stenosis": 6.492658880177509, "Coronary artery thrombosis": 13.128898685482104, "Decubitus ulcer": 2.065967387394839, "Deformity": 3.644134102377716, "Dermatitis exfoliative": 2.6210137666855515, "Dermatitis exfoliative generalised": 3.0302036058567574, "Device occlusion": 12.188039163219878, "Dieulafoy's vascular malformation": 28.773650699679507, "Discoloured vomit": 6.520799210643893, "Diverticulitis intestinal haemorrhagic": 29.51120427833756, "Diverticulum": 2.640446771164352, "Diverticulum intestinal haemorrhagic": 31.83007003235699, "Drug interaction": 2.716081632869062, "Duodenal ulcer": 12.41165459692926, "Duodenal ulcer haemorrhage": 28.28255813912088, "Duodenitis": 5.497788573664943, "Dysgraphia": 2.4320191371020456, "Ear haemorrhage": 9.299405690215972, "Ecchymosis": 8.869862175741625, "Embolic stroke": 4.019770195759928, "Enterocolitis haemorrhagic": 2.53314230941957, "Eosinophilic pneumonia": 2.718442840465225, "Epistaxis": 10.479617276839436, "Erosive duodenitis": 14.011890286933756, "Erosive oesophagitis": 4.323415021738636, "Erythema multiforme": 2.104785816598572, "Extradural haematoma": 14.32327272171473, "Eye haemorrhage": 9.71948768296904, "Faeces discoloured": 10.373396913124814, "Gastric haemorrhage": 22.326501796585944, "Gastric mucosal lesion": 5.214514073925921, "Gastric ulcer": 12.061340095384692, "Gastric ulcer haemorrhage": 34.877867677455946, "Gastric ulcer perforation": 4.851895480572279, "Gastritis": 3.8967190468221258, "Gastritis erosive": 12.551146650699216, "Gastritis haemorrhagic": 16.087951800199697, "Gastrointestinal haemorrhage": 58.13126904507781, "Gastrointestinal polyp haemorrhage": 18.222588473627383, "Gastrointestinal ulcer": 10.107347258778518, "Gastrointestinal ulcer haemorrhage": 29.11766531041668, "Gastrointestinal vascular malformation haemorrhagic": 63.68724138512445, "Gingival bleeding": 8.886655857877885, "Granulocytopenia": 4.275708434520027, "Haemarthrosis": 3.707840707673461, "Haematemesis": 17.435235208672296, "Haematochezia": 7.553392859692189, "Haematocrit decreased": 3.330424757461006, "Haematoma": 8.819041157016818, "Haematoma muscle": 9.281854365421433, "Haematuria": 12.12433556730448, "Haemobilia": 8.632726510367853, "Haemoglobin decreased": 4.203200460894481, "Haemoperitoneum": 6.823704548064068, "Haemoptysis": 8.709655599285693, "Haemorrhage": 15.745007499060966, "Haemorrhage intracranial": 13.363908847357235, "Haemorrhage subcutaneous": 31.569885389472077, "Haemorrhage urinary tract": 12.314906004058235, "Haemorrhagic arteriovenous malformation": 159.12407342389068, "Haemorrhagic cerebral infarction": 9.176649971180185, "Haemorrhagic diathesis": 11.203601975375484, "Haemorrhagic erosive gastritis": 17.45521327449445, "Haemorrhagic stroke": 29.186411200444876, "Haemorrhagic transformation stroke": 21.71155151268448, "Haemorrhoidal haemorrhage": 12.931834589154926, "Haemothorax": 8.131550718196586, "Head injury": 2.066906140273, "Hemiparesis": 2.915492458851386, "Hemiplegia": 5.543115699598892, "Hepatic function abnormal": 2.2845437700618003, "Hepatitis fulminant": 2.526990123689311, "Hepatocellular injury": 2.4151047445550007, "Hernia repair": 2.775467866205173, "Hiatus hernia": 2.282016149706135, "Hypochromic anaemia": 4.37444874164376, "Hypovolaemic shock": 5.3722670713647815, "Implant site fibrosis": 66.66762345310205, "Incision site haemorrhage": 11.314036481293806, "Increased tendency to bruise": 6.00188512340556, "Injury": 3.657837996516125, "Internal haemorrhage": 22.000627286243265, "International normalised ratio abnormal": 2.389022752485175, "International normalised ratio decreased": 2.6225695016405384, "International normalised ratio fluctuation": 3.311740313271792, "International normalised ratio increased": 3.9526396276768856, "Interstitial lung disease": 2.005801005039757, "Intestinal haemorrhage": 8.896400531193333, "Intra-abdominal haematoma": 9.324776955013547, "Intra-abdominal haemorrhage": 8.210247033277858, "Intracranial aneurysm": 4.168763969539065, "Intracranial haematoma": 19.372503057913644, "Intraventricular haemorrhage": 12.69434483881667, "Iron deficiency anaemia": 6.181051755205363, "Ischaemic stroke": 5.541996877129646, "Jaundice": 2.0954675873925663, "Labelled drug-drug interaction issue": 12.719068917991832, "Labelled drug-drug interaction medication error": 21.64832636522843, "Large intestinal haemorrhage": 15.84363446168183, "Large intestinal ulcer": 2.460863928126959, "Lip erosion": 3.27799375219679, "Loss of employment": 9.380733216575065, "Lower gastrointestinal haemorrhage": 33.276564058053346, "Mallory-Weiss syndrome": 10.188390947509518, "Melaena": 28.268636375387345, "Meningorrhagia": 20.746434550939004, "Microcytic anaemia": 7.309600669819747, "Mouth haemorrhage": 8.649762311659893, "Mucosal haemorrhage": 3.65884702379696, "Multiple injuries": 352.419921339594, "Muscle haemorrhage": 9.419930302962554, "Myocardial infarction": 5.374493988910676, "Non-cardiac chest pain": 2.1678820556606646, "Normochromic normocytic anaemia": 2.1959652531808382, "Normocytic anaemia": 4.63829797036092, "Occult blood positive": 23.0867056231374, "Oesophageal disorder": 2.7361597269126694, "Oesophageal haemorrhage": 19.129693117713806, "Oesophageal ulcer": 7.308732471703312, "Oesophageal ulcer haemorrhage": 19.721068503451477, "Oesophagitis": 3.257751035367675, "Oesophagitis ulcerative": 16.35825849537442, "Pelvic haematoma": 9.701518926134677, "Peptic ulcer": 4.693225092521799, "Peptic ulcer haemorrhage": 27.738932481006287, "Pericardial haemorrhage": 14.489711129154248, "Periorbital haematoma": 11.84825892951002, "Peripheral arterial occlusive disease": 4.5463611444110335, "Peripheral artery occlusion": 6.298263513127649, "Petechiae": 2.707303952900012, "Pharyngeal haemorrhage": 4.9139193713642, "Pharyngeal ulceration": 5.653326561836133, "Physical disability": 8.680829723214543, "Platelet function test abnormal": 51.64239492628506, "Polyp": 2.246117275205192, "Poor peripheral circulation": 2.3376860940110795, "Post procedural haematoma": 15.37349921412588, "Post procedural haemorrhage": 22.00160880947496, "Potentiating drug interaction": 2.329042344302027, "Prescribed overdose": 4.575458672889964, "Procedural haemorrhage": 9.986673642058348, "Product counterfeit": 24.48307202776711, "Prothrombin level decreased": 2.090735024750122, "Prothrombin time prolonged": 3.4876495367400646, "Psychological trauma": 36.86454495297246, "Pulmonary alveolar haemorrhage": 3.402200048721525, "Pulmonary haemorrhage": 5.627381722238279, "Puncture site haemorrhage": 10.86325334049841, "Purpura": 4.3207026578143655, "Putamen haemorrhage": 9.197430563161886, "Rebound effect": 2.2484792954503834, "Rectal haemorrhage": 20.23558244392888, "Renal artery stenosis": 4.384983350925937, "Renal haematoma": 13.70178300273248, "Renal haemorrhage": 8.940780619981064, "Respiratory tract haemorrhage": 11.71276628851296, "Retinal haemorrhage": 8.53118637722105, "Retroperitoneal haematoma": 11.3300107677197, "Retroperitoneal haemorrhage": 16.622110260283872, "Serum sickness": 2.7734326556356352, "Shock haemorrhagic": 19.30758978182237, "Skin haemorrhage": 5.329236524861156, "Small intestinal haemorrhage": 11.539631728331493, "Social problem": 5.500402765978257, "Spinal cord haematoma": 11.910748064275136, "Spinal epidural haematoma": 4.901532130784216, "Splenic haemorrhage": 15.064837405666031, "Spontaneous haematoma": 5.386013062339346, "Stent malfunction": 29.016339823534345, "Stent placement": 12.497315127215227, "Subarachnoid haemorrhage": 12.192642401738244, "Subcutaneous haematoma": 10.83269508356056, "Subdural haematoma": 30.882519613449368, "Subdural haemorrhage": 15.220917164294056, "Suspected counterfeit product": 5.928089952371267, "Tension": 3.797044566747124, "Thalamus haemorrhage": 11.219754066794302, "Thrombocytopenia": 2.80472136004551, "Thrombocytopenic purpura": 11.59214598646411, "Thrombosis": 2.866256195308674, "Thrombosis in device": 35.794174963850004, "Thrombotic thrombocytopenic purpura": 68.74921420691922, "Tongue haemorrhage": 7.9966166452974194, "Toxic skin eruption": 2.760824221496012, "Transient ischaemic attack": 6.968408762300268, "Traumatic haematoma": 20.1980851107826, "Traumatic haemorrhage": 10.824135349858803, "Traumatic intracranial haemorrhage": 25.096732539115838, "Tumour haemorrhage": 2.688393366943665, "Ulcer": 4.049655822917474, "Ulcer haemorrhage": 231.84255012365412, "Upper gastrointestinal haemorrhage": 34.87594095462303, "Urethral haemorrhage": 9.159013178477132, "Urinary bladder haemorrhage": 14.490012666603349, "Uterine haemorrhage": 2.4604278417703065, "Vascular graft": 6.806901537343005, "Vascular occlusion": 17.491052587296547, "Vascular pseudoaneurysm": 20.760981496459628, "Vascular stent occlusion": 54.42567877097595, "Vascular stent stenosis": 29.251861918176044, "Vascular stent thrombosis": 34.4684400166996, "Vessel puncture site haematoma": 20.92272383545631, "Vessel puncture site haemorrhage": 16.522763769161774, "Vitreous haemorrhage": 4.549600351482042, "Wound haemorrhage": 11.015713966811186}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/872.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/872.json
index d508445521a..049eaa59e9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/872.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/872.json
@@ -1 +1 @@
-{"Activated partial thromboplastin time prolonged ": 24.961551686533923, "Acute kidney injury ": 5.163366593166926, "Acute myocardial infarction ": 2.397096144436281, "Anaemia ": 4.271629460159758, "Atrial fibrillation ": 5.063531688034881, "Atrial flutter ": 9.031644623877863, "Blood loss anaemia ": 35.61284548976116, "Cardiac arrest ": 2.631377587274264, "Cardiac failure ": 3.289042336680393, "Cardio-respiratory arrest ": 2.5605745715425776, "Cerebral haematoma ": 11.21386438796598, "Cerebral haemorrhage ": 6.267278424431333, "Cerebral infarction ": 2.0183107372755544, "Cerebrovascular accident ": 3.0720222914856365, "Coagulopathy ": 29.09194849269363, "Contusion ": 2.201419407419697, "Drug interaction ": 4.688270490969302, "Embolic stroke ": 19.751723426223187, "Epistaxis ": 3.754822060273004, "Faeces discoloured ": 3.6572667401456633, "Fall ": 2.2324037129494694, "Gastric ulcer ": 5.929867627300556, "Gastritis ": 2.812516685960521, "Gastrointestinal haemorrhage ": 19.626319511374497, "Gingival bleeding ": 8.706464692511164, "Haematemesis ": 7.3812379416437315, "Haematochezia ": 5.525551301341769, "Haematoma ": 7.574085092707243, "Haematuria ": 8.11327325955491, "Haemoglobin decreased ": 3.710631514625412, "Haemoptysis ": 5.857052232169145, "Haemorrhage ": 7.992522673816503, "Haemorrhage intracranial ": 12.297014285110066, "Haemorrhagic stroke ": 15.779312018217611, "Haemothorax ": 29.608454478081047, "Hepatic cytolysis ": 3.5239655153759184, "Hepatitis cholestatic ": 5.7946689001960126, "Hyperkalaemia ": 3.3388951275698764, "Hypernatraemia ": 15.817071719979564, "Hyponatraemia ": 2.265995412356076, "Hypoxia ": 3.257346062597755, "International normalised ratio increased ": 6.653260931743654, "Iron deficiency anaemia ": 16.168148586892954, "Ischaemic stroke ": 4.107753456623793, "Lower gastrointestinal haemorrhage ": 24.7932824941684, "Lung disorder ": 3.127806483717644, "Malnutrition ": 9.52112891603238, "Melaena ": 16.646433690855105, "Multiple organ dysfunction syndrome ": 2.8223763014192222, "Oesophagitis ": 16.670901475394526, "Overdose ": 2.42582339372099, "Pancreatitis acute ": 2.6475803914390323, "Pleural effusion ": 2.0913078488472983, "Pneumonia ": 2.028671092264765, "Rectal haemorrhage ": 21.964013991013093, "Red blood cell count decreased ": 3.816201780561157, "Renal failure ": 2.779893202048421, "Septic shock ": 3.2376325429390915, "Shock ": 4.418301622348394, "Shock haemorrhagic ": 27.35712337530486, "Subarachnoid haemorrhage ": 8.723218035085091, "Subdural haematoma ": 10.348954693550738, "Sudden death ": 7.912163178128317, "Toxic epidermal necrolysis ": 3.1513804044082283, "Transient ischaemic attack ": 2.454275727849093, "Upper gastrointestinal haemorrhage ": 9.404583033498373}
\ No newline at end of file
+{"Abortion spontaneous": 2.4806738283027343, "Accidental underdose": 26.658821280480822, "Balance disorder": 2.187872310662532, "Blindness unilateral": 2.492668133578598, "Blood test abnormal": 8.543275135642038, "Breast cancer female": 8.168909721700714, "Caesarean section": 5.178243503157975, "Central nervous system lesion": 9.475718423097147, "Cognitive disorder": 2.043260792377162, "Coronavirus infection": 13.05535054587532, "Decreased immune responsiveness": 3.8680999406553305, "Depressed mood": 3.5916439946584973, "Depression": 2.0401299863824818, "Device malfunction": 3.224126797843517, "Drug delivery system malfunction": 607.3147797123646, "Drug dose omission by device": 80.53672255380215, "Drug intolerance": 2.0374126080110795, "Full blood count abnormal": 4.91205944294301, "Gait disturbance": 2.074385705497779, "Gamma-glutamyltransferase increased": 2.384532037172422, "Incorrect dose administered by device": 11.83454769491556, "Influenza": 3.08540630339942, "Influenza like illness": 18.218513046108765, "Injection site bruising": 25.98200335223188, "Injection site discolouration": 46.10955362881223, "Injection site erythema": 21.808651621567304, "Injection site extravasation": 6.395704767778714, "Injection site haematoma": 4.66596807066349, "Injection site haemorrhage": 62.8092867143474, "Injection site induration": 7.857432252556512, "Injection site injury": 53.56760734289673, "Injection site irritation": 25.929932059534416, "Injection site mass": 3.721986659731683, "Injection site necrosis": 8.0843466617031, "Injection site oedema": 5.233809979072314, "Injection site pain": 2.6443822615906623, "Injection site pruritus": 11.829091263186625, "Injection site rash": 35.01971771916899, "Injection site reaction": 16.927750627550914, "Injection site urticaria": 11.9184994774649, "Injection site warmth": 2.4402857697175904, "Injury associated with device": 55.38351522912368, "Lack of injection site rotation": 49.50365593678025, "Leukopenia": 4.762837810840984, "Listless": 3.3464724252192157, "Liver function test increased": 9.287184710405649, "Loss of control of legs": 17.10173810480187, "Lymphocyte count decreased": 8.919910410133243, "Lymphopenia": 11.68766181261934, "Magnetic resonance imaging abnormal": 23.643108950479967, "Maternal exposure during pregnancy": 2.7817378651512747, "Memory impairment": 2.0019118745045543, "Mobility decreased": 2.693374079360833, "Motor dysfunction": 6.742709486838122, "Multiple sclerosis": 42.04423185214561, "Multiple sclerosis relapse": 67.4278312661942, "Muscle spasticity": 4.959433517554394, "Musculoskeletal disorder": 9.785486587622117, "Nasopharyngitis": 2.984396220471349, "Optic neuritis": 5.263842198407787, "Prescribed underdose": 2.39238349805812, "Product administered at inappropriate site": 6.099888023583092, "Product dose omission in error": 6.079571073988488, "Product dose omission issue": 9.963426439023362, "SARS-CoV-2 test positive": 2.343851627991173, "Secondary progressive multiple sclerosis": 62.94658911090108, "Skin reaction": 5.574485548038685, "Stress": 3.991988961682665, "Urosepsis": 3.757449817191576, "White blood cell count abnormal": 6.078209131308134}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/873.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/873.json
index f611df9cddd..dd19c7c8c4d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/873.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/873.json
@@ -1 +1 @@
-{"Myalgia ": 2.5189684738246845}
\ No newline at end of file
+{"Anaemia": 6.154551369580945, "Disease progression": 11.69657544309274, "Dry mouth": 5.745062973842336, "General physical health deterioration": 35.30781526467567, "Haemoglobin decreased": 5.849302182717402, "Hormone-refractory prostate cancer": 628.3275672818521, "Ill-defined disorder": 167.9114742317682, "Laboratory test abnormal": 34.39272569593107, "Malignant neoplasm progression": 16.76075496028068, "Metastases to bone": 24.338396053255607, "Neoplasm malignant": 6.092625850982343, "Pancytopenia": 10.108843906607506, "Platelet count decreased": 3.9813956249594415, "Prostate cancer": 33.937123438531856, "Prostate cancer metastatic": 206.69547058818415, "Prostatic specific antigen increased": 100.62671114972268, "Thrombocytopenia": 7.0976049812841175}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/874.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/874.json
index c7e1cb0297f..ad0c6059718 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/874.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/874.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 3.025812279689638, "Condition aggravated ": 2.5570218399762155, "Hallucination ": 20.583403914815182, "Hyperhidrosis ": 3.4731125668744016, "Insomnia ": 2.9811683868457397, "Oedema peripheral ": 11.577403354098026, "Off label use ": 2.088606678539077, "Product use in unapproved indication ": 3.251001727753705, "Somnolence ": 6.535247268881274, "Suicidal ideation ": 5.748310049704841}
\ No newline at end of file
+{"Diffuse large B-cell lymphoma": 173.55008313044877, "Disease progression": 51.12181642365399, "Drug ineffective": 2.100166897012626, "Febrile neutropenia": 12.957173569799156, "Off label use": 2.5063071163694035, "Thrombocytopenia": 3.8795316123671806}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/875.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/875.json
index 5fba75b1b97..f057c343764 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/875.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/875.json
@@ -1 +1 @@
-{"Blood glucose increased ": 8.331648465286401, "Hypoglycaemia ": 13.256137182522496, "Hypoglycaemic coma ": 104.73430579604802}
\ No newline at end of file
+{"Febrile convulsion": 218.4369009541496, "Pyrexia": 2.2848559526877184}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/876.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/876.json
index 6cc3d5ed720..dbb5c0752a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/876.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/876.json
@@ -1 +1 @@
-{"Central sleep apnoea syndrome ": 484.4571737531444, "Cerebral haemorrhage ": 12.274174471349715, "Contusion ": 3.237816455384399, "Drug interaction ": 2.4139264743665376, "Epistaxis ": 12.837270121920746, "Gastrointestinal haemorrhage ": 19.494778613008457, "Haematoma ": 14.338691378773008, "Haematuria ": 7.953078222226222, "Haemoglobin decreased ": 3.027589736469331, "Haemorrhage intracranial ": 24.23070147526959, "Labelled drug-drug interaction medication error ": 92.53361777587648, "Melaena ": 12.140570065458991, "Myocardial infarction ": 2.8012780644058526, "Product administration error ": 23.65792598113279, "Rectal haemorrhage ": 11.713073360486606, "Shock haemorrhagic ": 35.73287990223736, "Subdural haematoma ": 15.92770024575651, "Upper gastrointestinal haemorrhage ": 19.26522008686017}
\ No newline at end of file
+{"Disease progression": 108.19691133660572, "Off label use": 2.7485433873782674}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/877.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/877.json
index 643483d6c25..1571135fef9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/877.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/877.json
@@ -1 +1 @@
-{"Activated partial thromboplastin time prolonged ": 38.83887178682311, "Acute kidney injury ": 3.549487394962596, "Anticoagulation drug level increased ": 1055.8045558201163, "Cardiac arrest ": 4.893297045316147, "Cardiac failure ": 2.7971980420437683, "Cardio-respiratory arrest ": 5.181493971611359, "Cerebral haemorrhage ": 26.30702910336432, "Cerebral infarction ": 9.949272502517452, "Cerebrovascular accident ": 3.7347593578278153, "Coagulopathy ": 26.50508909634756, "Death ": 11.061784302431493, "Gastrointestinal haemorrhage ": 16.882217703784267, "General physical health deterioration ": 2.672000515512168, "Haematuria ": 6.530516502713406, "Haemoglobin decreased ": 3.149704181373004, "Haemorrhage ": 22.571761085566408, "Haemorrhage intracranial ": 66.54078888492823, "Haemorrhagic transformation stroke ": 384.43779001517566, "Ischaemic stroke ": 24.57065142055085, "Melaena ": 9.138734031875424, "Multiple organ dysfunction syndrome ": 20.3051244338344, "Pneumonia ": 2.6466164708829947, "Pulmonary embolism ": 3.630379172301986, "Renal failure ": 2.3720935026661145, "Respiratory failure ": 4.29750238687017, "Sepsis ": 7.372706732497508, "Septic shock ": 19.5186778324819, "Shock ": 9.637777716063638, "Shock haemorrhagic ": 42.25465395635633}
\ No newline at end of file
+{"Anaemia": 4.26577283893718, "Atrial fibrillation": 3.820258512782803, "Cardiac failure": 2.3932549007837505, "Cytopenia": 17.33861021906855, "Death": 2.189212578989232, "Disease progression": 5.831834399454936, "Febrile neutropenia": 10.36837363089763, "General physical health deterioration": 3.289642555122611, "Infection": 4.520905249254847, "Lower respiratory tract infection": 4.200290165033403, "Neuropathy peripheral": 7.941340405079102, "Neutropenia": 14.257942070608795, "Neutrophil count decreased": 5.179085481389913, "Pancytopenia": 9.382844790844969, "Plasma cell myeloma": 168.79004554642137, "Plasma cell myeloma recurrent": 93.22531068431744, "Plasmacytoma": 119.62528421273352, "Platelet count decreased": 2.410954945456092, "Pneumonia": 7.950677044320015, "Pulmonary embolism": 2.657763824979871, "Renal impairment": 2.41829284738506, "Sepsis": 7.631524782308808, "Thrombocytopenia": 4.69027099640254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/878.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/878.json
index cf649b78e0a..87b946e480b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/878.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/878.json
@@ -1 +1 @@
-{"Accidental death ": 18.51097915813447, "Accidental overdose ": 11.227251486781157, "Acute pulmonary oedema ": 2.921651623425848, "Aggression ": 4.57899622752631, "Agitation ": 3.620184751892669, "Alcohol abuse ": 11.517031584299016, "Alcohol poisoning ": 19.3063797893705, "Altered state of consciousness ": 3.472719776905267, "Anger ": 3.967795546441717, "Anorgasmia ": 11.818784617089475, "Arteriosclerosis ": 3.53206336569775, "Arteriosclerosis coronary artery ": 3.757076249431161, "Asphyxia ": 2.83261731274444, "Aspiration ": 4.669360870234154, "Bacterial infection ": 3.166634537611632, "Behaviour disorder ": 3.819263581851737, "Bradyphrenia ": 2.952202208670751, "Bradypnoea ": 27.22460288554129, "Brain injury ": 6.0751432003971, "Breath sounds abnormal ": 8.585482710437963, "Cardiac arrest ": 5.010893064646591, "Cardio-respiratory arrest ": 4.437066995070747, "Cholestasis ": 2.75773629733525, "Chronic sinusitis ": 31.531845583851723, "Cognitive disorder ": 3.099325484779051, "Colitis ": 7.974339262640269, "Colitis ulcerative ": 8.470413652480138, "Coma ": 9.480153993379984, "Coma scale abnormal ": 19.386375464111808, "Completed suicide ": 8.08889190626819, "Constipation ": 3.4754552153794123, "Cutaneous vasculitis ": 4.231606036991863, "Delirium ": 2.4183109664307887, "Dependence ": 4.957490411327145, "Depressed level of consciousness ": 7.885692769161086, "Disturbance in attention ": 2.4714881848837846, "Drug abuse ": 18.82519772823964, "Drug dependence ": 6.755600760859724, "Drug diversion ": 8.132524143270455, "Drug effect less than expected ": 8.099993366020223, "Drug ineffective for unapproved indication ": 2.571178608871597, "Drug interaction ": 3.171824821790138, "Drug level increased ": 4.928880430277475, "Drug use disorder ": 22.54446343863576, "Dysarthria ": 5.006100644134078, "Dyskinesia ": 2.751405115170214, "Dyspepsia ": 3.781655993772897, "Encephalopathy ": 2.895270010690523, "Eosinophilia ": 5.769549343877478, "Fall ": 2.1918171236314468, "Feeling drunk ": 3.09232147334965, "Female genital tract fistula ": 45.77806559339229, "Foaming at mouth ": 23.09488376151867, "Frequent bowel movements ": 16.29850977187622, "Full blood count abnormal ": 3.678880157178435, "Haematochezia ": 5.211406089267794, "Hallucination, visual ": 2.5856107724894604, "Hepatic cytolysis ": 2.127093626981684, "Hepatic steatosis ": 3.58156528209786, "Hormone level abnormal ": 3.23126701580303, "Hypercapnia ": 8.025811553870865, "Hypothermia ": 2.254572635668405, "Hypovolaemia ": 3.4382222589754106, "Impaired driving ability ": 3.151123067066041, "Inadequate analgesia ": 16.694727020514254, "Infusion related reaction ": 5.042370566723563, "Intentional overdose ": 4.761976522278563, "Intentional product misuse ": 7.825524793513819, "Intentional self-injury ": 4.461698494727343, "Iron deficiency ": 11.36202917709176, "Lip discolouration ": 45.517006873899646, "Metabolic disorder ": 4.542569620838044, "Middle insomnia ": 10.034790778955744, "Miosis ": 16.05252066141492, "Multiple sclerosis ": 2.3627923084863034, "Muscle tightness ": 3.4329693007340705, "Mydriasis ": 9.183884803163398, "Myoclonus ": 6.533716064282663, "Nervous system disorder ": 2.526718538532097, "Obstructive airways disorder ": 6.287911342908376, "Oral candidiasis ": 17.107783150326775, "Overdose ": 4.651389877313613, "Pallor ": 2.030004192953974, "Paraesthesia oral ": 7.514113204656563, "Parkinsonism ": 4.160283368146442, "Pneumonia aspiration ": 3.7271783833101817, "Poisoning ": 9.93551915483845, "Poisoning deliberate ": 13.702285488775294, "Potentiating drug interaction ": 8.965748019361003, "Prescription drug used without a prescription ": 31.10758205898569, "Procedural pain ": 28.296959539094143, "Proctitis ": 40.00546335312899, "Product prescribing error ": 5.014435051271363, "Productive cough ": 2.982245868860357, "Radiculopathy ": 35.53232718068973, "Rectal haemorrhage ": 6.642027657403015, "Respiratory arrest ": 8.669423627406777, "Respiratory depression ": 13.005283061050667, "Rhabdomyolysis ": 3.397886671031312, "Schizophrenia ": 5.1039402573675785, "Sedation ": 5.442925781659223, "Sedation complication ": 4.508408088396333, "Sinus bradycardia ": 6.626391811205769, "Skin ulcer ": 2.615663611675052, "Snoring ": 28.22558461408178, "Somnolence ": 3.577890070124957, "Substance abuse ": 6.817975541651941, "Substance use disorder ": 7.886679416431402, "Suicide attempt ": 2.683164843290036, "Suspected suicide ": 9.292541613543138, "Therapeutic product effect incomplete ": 6.304788063413934, "Tooth disorder ": 4.295694388067568, "Tourette's disorder ": 31.937128994645622, "Toxic encephalopathy ": 3.913110704080435, "Toxicity to various agents ": 20.894681179740235, "Trigeminal neuralgia ": 3.833703533315884, "Unresponsive to stimuli ": 4.056920614478486, "Vaginal discharge ": 25.111935198961216, "Vaginal flatulence ": 54.33823920804201, "Withdrawal syndrome ": 7.906637350333737, "Wrong patient received product ": 10.027893139317698}
\ No newline at end of file
+{"Blood creatinine increased": 10.010033682439452, "Renal artery angioplasty": 9805.99548923163, "Renal artery stenosis": 587.1133236146788, "Renal artery stent placement": 3435.407529657426}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/879.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/879.json
index 3a27c2f9af0..d4a634a1c21 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/879.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/879.json
@@ -1 +1 @@
-{"Blood alkaline phosphatase increased ": 23.79542210462477, "Blood calcium increased ": 121.49477305195362, "Decreased appetite ": 2.297170738181346, "Hypercalcaemia ": 273.23643781903644, "Nausea ": 2.5397828714246398, "Palpitations ": 3.195143846090982, "Spinal fracture ": 50.47369314178402, "Weight decreased ": 5.452312202527639}
\ No newline at end of file
+{"Coma": 7.324679340334201, "Cyanosis": 17.35906028025996, "Drug abuse": 128.15299715990255, "Drug dependence": 7.356793977485433, "Euphoric mood": 290.2125957149228, "Feeling abnormal": 6.676952248725892, "Feeling of relaxation": 8195.362592278176, "Insomnia": 3.797002348937057, "Memory impairment": 22.02625791205271, "Oxygen saturation decreased": 14.794796854259648, "Poisoning": 59.76871710773202, "Sleep disorder": 6.328261912149192, "Substance abuse": 128.38687960271358, "Tachycardia": 2.351733151265251, "Toxicity to various agents": 3.022339210321896, "Vision blurred": 5.002092310136744, "Withdrawal syndrome": 18.629403926374323}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/88.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/88.json
index f8931503001..0dd18ba674a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/88.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/88.json
@@ -1 +1 @@
-{"Completed suicide ": 10.70798892837862, "Drug dependence ": 17.39829051045501, "Overdose ": 7.557112045353668, "Substance abuse ": 90.91997633762354}
\ No newline at end of file
+{"Toxicity to various agents": 34.113043035237474}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/880.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/880.json
index 843608032c5..958d8c83bab 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/880.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/880.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 19.842860680126417, "Aspartate aminotransferase increased ": 20.78805621349088, "Electrocardiogram QT prolonged ": 22.08900263208421}
\ No newline at end of file
+{"Acute kidney injury": 2.1297187683257275, "Aspergillus infection": 30.36901757396796, "Blood bilirubin increased": 2.3390358965387645, "Bronchopulmonary aspergillosis": 13.653872966793005, "Candida infection": 13.488552157105609, "Cholestasis": 5.063814515427367, "Condition aggravated": 2.6823732668275038, "Disease progression": 3.227390373072085, "Drug ineffective": 5.58505470451031, "Drug ineffective for unapproved indication": 10.785472909912825, "Drug interaction": 16.904420404916365, "Drug level below therapeutic": 86.68917342704319, "Drug level decreased": 18.90997515650169, "Drug level increased": 10.8114680578307, "Drug resistance": 9.194598382781573, "Drug-induced liver injury": 3.06996057318879, "Electrocardiogram QT prolonged": 3.563099572978805, "Encephalopathy": 11.507125946877672, "Febrile neutropenia": 2.3914653118216247, "Fungaemia": 63.97711774661576, "Fungal infection": 22.56871578978878, "Graft versus host disease": 16.864822357495758, "Hallucination, visual": 5.696964522562297, "Hepatic cytolysis": 7.092548135780718, "Hepatotoxicity": 8.128528294553155, "Hyperbilirubinaemia": 5.946134570743815, "Hypokalaemia": 5.980548155225688, "Hypomagnesaemia": 13.744022326403568, "Ileus paralytic": 19.061689494692185, "Iridocyclitis": 28.55487422693647, "Mental status changes": 6.86516154137159, "Mucormycosis": 71.80780084153649, "Multiple organ dysfunction syndrome": 4.38267615005681, "Nephropathy toxic": 7.330339632259821, "Neurotoxicity": 15.0974259307694, "Neutropenia": 2.325323965874867, "Off label use": 2.182216444125096, "Pancytopenia": 2.1410013034757966, "Pathogen resistance": 56.69041788506062, "Pneumonia fungal": 48.1700031930461, "Posterior reversible encephalopathy syndrome": 14.205863310938328, "Primary adrenal insufficiency": 333.4399540432499, "Product use in unapproved indication": 4.672620039282708, "Product use issue": 2.611424123893368, "Pseudoaldosteronism": 792.8375288062289, "Rash maculo-papular": 6.827515000791375, "Renal disorder": 3.7153603885182775, "Renal impairment": 3.117155697899431, "Respiratory failure": 4.212917138258193, "Rhabdomyolysis": 4.701720694925154, "Septic shock": 5.027440280304012, "Sinusitis": 2.3034153117200864, "Systemic mycosis": 157.89058464323432, "Torsade de pointes": 16.209239521131057, "Treatment failure": 5.610299930096147, "Ventricular tachycardia": 5.101424818547481}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/881.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/881.json
index 3b0014691bf..0bd1f95acae 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/881.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/881.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 2.0316697162902413, "Allergy to metals ": 103.4896340748829, "Anaphylactic reaction ": 2.6719949065830777, "Apathy ": 3.4146565422771413, "Apnoea ": 19.58757845662804, "Autism spectrum disorder ": 28.46206393260012, "Cardio-respiratory arrest ": 2.119375581134088, "Choking ": 3.440455028525097, "Conjunctivitis ": 5.461493573092191, "Crying ": 30.895838871539688, "Cyanosis ": 14.652702315393851, "Decreased appetite ": 2.096611770759232, "Developmental delay ": 8.455937997491173, "Dyskinesia ": 2.690482314826129, "Eczema ": 2.9660772002206333, "Erythema ": 2.3628016484197567, "Erythema multiforme ": 3.523600250929058, "Eye movement disorder ": 6.301527756001803, "Febrile convulsion ": 58.6699166913204, "Flatulence ": 2.615509628668609, "Gastroenteritis ": 5.923794995236322, "Gastroenteritis rotavirus ": 29.039990802144693, "Gaze palsy ": 32.24226145336513, "Guillain-Barre syndrome ": 4.573572164922204, "Haematochezia ": 13.089426427898417, "Hyperpyrexia ": 9.054315793598729, "Hyporesponsive to stimuli ": 33.332672706494805, "Hypotonia ": 13.220615682185338, "Hypotonic-hyporesponsive episode ": 61.33236573240623, "Immune thrombocytopenia ": 25.78481329817391, "Immunisation reaction ": 2.1891079209458777, "Infantile vomiting ": 192.17734624387012, "Intussusception ": 219.9261752253154, "Irritability ": 9.285284864811803, "Irritability postvaccinal ": 29.0074078727816, "Kawasaki's disease ": 157.69709419386817, "Local reaction ": 4.1383523031394045, "Measles ": 23.523625146675386, "Mood altered ": 6.950834823899874, "Mucous stools ": 16.423148171415633, "Otitis media ": 17.971332406303574, "Pallor ": 15.129014270833386, "Petechiae ": 10.01083318556207, "Pharyngitis ": 4.413218079527683, "Presyncope ": 2.011442219048233, "Product administered to patient of inappropriate age ": 11.787694360646636, "Purpura ": 6.663251033504417, "Pyrexia ": 3.4804902135149423, "Rash ": 2.0251166961042397, "Rash macular ": 3.7838574689351647, "Rash maculo-papular ": 2.4936435357451887, "Rash morbilliform ": 10.694546844844876, "Reaction to excipient ": 27.390414591103124, "Respiratory arrest ": 3.918616804685032, "Restlessness ": 8.435183808845776, "Rhinorrhoea ": 5.32850482029045, "Scratch ": 19.639214333628622, "Screaming ": 33.56137946092968, "Seizure ": 3.892739271317128, "Skin wound ": 46.76304399660237, "Speech disorder developmental ": 20.707825926869564, "Staring ": 17.586787577628197, "Sudden death ": 4.549799579895668, "Sudden infant death syndrome ": 93.29158502596154, "Thrombocytopenic purpura ": 44.74746314121028, "Unresponsive to stimuli ": 6.618483593562401, "Upper respiratory tract infection ": 4.000349251026849, "Urticaria ": 2.1173654720942245, "Vaccination complication ": 59.395613897084125, "Vaccination site erythema ": 3.684474335846635, "Vaccination site granuloma ": 114.20945933702082, "Vaccination site hypertrichosis ": 342.1343021457868, "Vaccination site induration ": 7.061710007891035, "Vaccination site pruritus ": 4.205430539214654, "Vaccination site reaction ": 2.2693349546213417, "Vaccination site swelling ": 2.9182893696500334, "Viral infection ": 10.499621307716886}
\ No newline at end of file
+{"Disease progression": 26.95664593429937, "Drug eruption": 46.130976230340174, "Hypercalcaemia": 18.129281781054377, "Inappropriate schedule of product administration": 4.570649351721388, "Infusion related reaction": 31.61374002051957, "Leukopenia": 2.787678683920146, "Liver disorder": 4.941759699053839, "Lymphopenia": 62.31663035119141, "Myocarditis": 7.022884251373756, "Rash": 3.850440775170687, "Sepsis": 6.685246545295988, "Toxic epidermal necrolysis": 10.77964029755511, "Tumour lysis syndrome": 30.5488812903053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/882.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/882.json
index c22028b0f49..385155559d6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/882.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/882.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.1924191014279493, "Acute kidney injury ": 2.3436097849343023, "Drug interaction ": 5.520842174979796, "Exposure during pregnancy ": 10.666659023449665, "Hepatic enzyme increased ": 6.63038261211724, "Immune reconstitution inflammatory syndrome ": 115.58123582248996, "Rash ": 2.618855389993735, "Rash maculo-papular ": 8.311663762314943}
\ No newline at end of file
+{"Activated partial thromboplastin time prolonged": 24.961551686533923, "Acute kidney injury": 5.163366593166926, "Acute myocardial infarction": 2.397096144436281, "Anaemia": 4.271629460159758, "Atrial fibrillation": 5.063393333992227, "Atrial flutter": 9.031644623877863, "Blood loss anaemia": 35.61284548976116, "Cardiac arrest": 2.631377587274264, "Cardiac failure": 3.2887419475183908, "Cardio-respiratory arrest": 2.5605745715425776, "Cerebral haematoma": 11.21386438796598, "Cerebral haemorrhage": 6.267278424431333, "Cerebral infarction": 2.0183107372755544, "Cerebrovascular accident": 3.0719669009051547, "Coagulopathy": 29.09194849269363, "Contusion": 2.201419407419697, "Drug interaction": 4.688270490969302, "Embolic stroke": 19.751723426223187, "Epistaxis": 3.754822060273004, "Faeces discoloured": 3.6572667401456633, "Fall": 2.232346464610201, "Gastric ulcer": 5.925922712000488, "Gastritis": 2.812516685960521, "Gastrointestinal haemorrhage": 19.626319511374497, "Gingival bleeding": 8.706464692511164, "Haematemesis": 7.380582367365746, "Haematochezia": 5.525004349581445, "Haematoma": 7.574085092707243, "Haematuria": 8.11327325955491, "Haemoglobin decreased": 3.710631514625412, "Haemoptysis": 5.857052232169145, "Haemorrhage": 7.992522673816503, "Haemorrhage intracranial": 12.297014285110066, "Haemorrhagic stroke": 15.779312018217611, "Haemothorax": 29.608454478081047, "Hepatic cytolysis": 3.5239655153759184, "Hepatitis cholestatic": 5.7946689001960126, "Hyperkalaemia": 3.3384345672024405, "Hypernatraemia": 15.817071719979564, "Hyponatraemia": 2.265995412356076, "Hypoxia": 3.257346062597755, "International normalised ratio increased": 6.653260931743654, "Iron deficiency anaemia": 16.162394879373352, "Ischaemic stroke": 4.107753456623793, "Lower gastrointestinal haemorrhage": 24.7932824941684, "Lung disorder": 3.127806483717644, "Malnutrition": 9.52112891603238, "Melaena": 16.644279443692096, "Multiple organ dysfunction syndrome": 2.8223763014192222, "Oesophagitis": 16.670901475394526, "Overdose": 2.42582339372099, "Pancreatitis acute": 2.6475803914390323, "Pleural effusion": 2.0911152706021423, "Pneumonia": 2.028671092264765, "Rectal haemorrhage": 21.964013991013093, "Red blood cell count decreased": 3.816201780561157, "Renal failure": 2.779893202048421, "Septic shock": 3.2376325429390915, "Shock": 4.418301622348394, "Shock haemorrhagic": 27.35712337530486, "Subarachnoid haemorrhage": 8.723218035085091, "Subdural haematoma": 10.348954693550738, "Sudden death": 7.912163178128317, "Toxic epidermal necrolysis": 3.1513804044082283, "Transient ischaemic attack": 2.454275727849093, "Upper gastrointestinal haemorrhage": 9.402025287771975}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/883.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/883.json
index 7e520017f93..040c0e60a11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/883.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/883.json
@@ -1 +1 @@
-{"Anxiety ": 2.998800227940469, "Blood pressure increased ": 2.0026373772275017, "Cardiac arrest ": 6.58525693726546, "Chest X-ray abnormal ": 105.50992778025244, "Confusional state ": 4.004864637665608, "Drug withdrawal syndrome ": 24.6190452188728, "Feeling abnormal ": 3.3862928186652064, "Hallucination ": 9.680678579928584, "Loss of consciousness ": 6.701840247718767, "Memory impairment ": 4.426920092772397, "Mental status changes ": 19.506438340585365, "Off label use ": 3.0059477027440256, "Overdose ": 8.329305050587235, "Pain ": 2.6518190039929026, "Respiratory failure ": 9.262384727484022, "Sinus bradycardia ": 44.4033289509607, "Unresponsive to stimuli ": 30.15673968952885, "Urinary tract infection ": 6.586118734352913, "Withdrawal syndrome ": 15.497529369547182}
\ No newline at end of file
+{"Myalgia": 2.5028559995843387}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/884.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/884.json
index 466dd0ede11..59fe220896b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/884.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/884.json
@@ -1 +1 @@
-{"Alopecia ": 24.917605499852616, "Drug ineffective ": 5.444529373731919, "Pruritus ": 8.92112050689733}
\ No newline at end of file
+{"Abdominal discomfort": 3.025812279689638, "Condition aggravated": 2.5570218399762155, "Hallucination": 20.583403914815182, "Hyperhidrosis": 3.4731125668744016, "Insomnia": 2.9811683868457397, "Oedema peripheral": 11.577117193871214, "Off label use": 2.088524419080668, "Product use in unapproved indication": 3.2509003547835342, "Somnolence": 6.535175224394134, "Suicidal ideation": 5.748310049704841}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/885.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/885.json
index 6f2001ee530..775b6423772 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/885.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/885.json
@@ -1 +1 @@
-{"Acute kidney injury ": 8.015651642333145, "Angioedema ": 6.576439548123348, "Blood pressure increased ": 4.776165062191402, "Hyperkalaemia ": 10.57789017706332, "Hypertension ": 2.591275157070762, "Hyponatraemia ": 6.851189071467454, "Hypotension ": 8.082714785579464, "Lactic acidosis ": 11.059916099594156, "Syncope ": 5.539313156083034, "Therapy non-responder ": 13.038655792751152, "Urinary retention ": 8.228538927804658}
\ No newline at end of file
+{"Blood glucose increased": 8.331648465286401, "Hypoglycaemia": 13.255689746409368, "Hypoglycaemic coma": 104.73430579604802}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/886.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/886.json
index 61311242112..d44158e87a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/886.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/886.json
@@ -1 +1 @@
-{"Acute kidney injury ": 5.06486137229661, "Hypokalaemia ": 15.130603851658217, "Hyponatraemia ": 43.86941329753903, "Hypotension ": 12.778253573492035, "Orthostatic hypotension ": 80.7792087104857, "Presyncope ": 15.515070674962002, "Syncope ": 5.122572817708822}
\ No newline at end of file
+{"Central sleep apnoea syndrome": 484.4571737531444, "Cerebral haemorrhage": 12.274174471349715, "Contusion": 3.237816455384399, "Drug interaction": 2.4139264743665376, "Epistaxis": 12.837270121920746, "Gastrointestinal haemorrhage": 19.494778613008457, "Haematoma": 14.338691378773008, "Haematuria": 7.953078222226222, "Haemoglobin decreased": 3.027589736469331, "Haemorrhage intracranial": 24.23070147526959, "Labelled drug-drug interaction medication error": 92.53361777587648, "Melaena": 12.13900453194327, "Myocardial infarction": 2.8012780644058526, "Product administration error": 23.65607156817275, "Rectal haemorrhage": 11.713073360486606, "Shock haemorrhagic": 35.73287990223736, "Subdural haematoma": 15.92770024575651, "Upper gastrointestinal haemorrhage": 19.259988107923004}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/887.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/887.json
index 475059ff9c1..50ffc748e20 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/887.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/887.json
@@ -1 +1 @@
-{"Acute pulmonary oedema ": 6.1841997790620615, "Allergic transfusion reaction ": 272.9148648519022, "Anaphylactic reaction ": 3.961812408145085, "Anaphylactoid reaction ": 3.1710018807822, "Anti A antibody positive ": 411.1213401477086, "Anti-erythrocyte antibody ": 319.5880767178647, "Anti-erythrocyte antibody positive ": 730.083056576617, "Autoimmune haemolytic anaemia ": 3.6635580061077113, "Back pain ": 2.6356742134845845, "Bacteraemia ": 7.2704653184229, "Blood lactate dehydrogenase increased ": 3.3082874692811566, "Blood pressure decreased ": 2.029604099352155, "Blood pressure increased ": 2.722239161204472, "Body temperature increased ": 3.790242614227624, "Bronchospasm ": 4.148995036433701, "Chills ": 3.014999674561454, "Chromaturia ": 2.622878860751225, "Chronic inflammatory demyelinating polyradiculoneuropathy ": 29.24673654037771, "Coombs direct test positive ": 210.28683316964447, "Cyanosis ": 4.118398060471376, "Delayed haemolytic transfusion reaction ": 495.6868531747263, "Dermatitis allergic ": 3.23224443753568, "Dermatitis exfoliative generalised ": 2.0205750252300785, "Device related infection ": 2.9943085932331317, "Drug ineffective for unapproved indication ": 5.125674555785447, "Dyshidrotic eczema ": 26.660673261154635, "Dyspnoea ": 2.0678915008373484, "Eczema ": 4.765227278160462, "Extravasation ": 12.787199123165037, "Febrile nonhaemolytic transfusion reaction ": 317.7727198394914, "Feeling cold ": 2.475796150970327, "Flank pain ": 3.1278612369409178, "Flushing ": 5.949458327414318, "Gynaecomastia ": 3.709308692450034, "Haemoglobin decreased ": 4.920588638963006, "Haemoglobinuria ": 53.542714015237856, "Haemolysis ": 61.155702214235205, "Haemolytic anaemia ": 31.21080953731264, "Haptoglobin decreased ": 36.938125840309176, "Heart rate increased ": 2.19595753276031, "Hepatitis B ": 10.453215321051678, "Hepatitis B core antibody positive ": 208.86329001087176, "Hepatitis B surface antibody positive ": 195.02144887657207, "Hyper IgE syndrome ": 899.2415428498616, "Hyperpyrexia ": 2.0282736378861026, "Hypersensitivity ": 2.934393403044051, "Hypertension ": 3.20228563213158, "Hyperthermia ": 7.607573797966813, "Hypervolaemia ": 5.634730193326282, "Hypotension ": 2.63594851614826, "Hypothermia ": 2.376735416412435, "Hypoxia ": 7.532469597979104, "Incorrect drug administration rate ": 37.95988970092924, "Infusion related reaction ": 4.275398723087484, "Infusion site erythema ": 7.022568771584545, "Infusion site extravasation ": 13.581766027170556, "Infusion site swelling ": 8.981761725849443, "Intravascular haemolysis ": 39.990700029654185, "Livedo reticularis ": 19.03912835262059, "Lung infiltration ": 2.6600506191558626, "Meningeal disorder ": 51.82943737253477, "Meningism ": 43.225935869015366, "Meningitis ": 6.605751755991852, "Meningitis aseptic ": 180.9170365490505, "Musculoskeletal stiffness ": 3.0584277161268454, "Myasthenia gravis ": 2.5122200044316805, "Neck pain ": 2.193681865750557, "No adverse event ": 43.07986275294141, "Nuchal rigidity ": 22.847411545135053, "Oxygen saturation decreased ": 8.897954141189457, "Pallor ": 2.6533243868124803, "Phonophobia ": 25.714108279276303, "Photophobia ": 9.29597606194154, "Pneumonia staphylococcal ": 23.70586074885136, "Product use in unapproved indication ": 2.2924063894471667, "Pulmonary embolism ": 2.0149134485371296, "Rash pruritic ": 2.1022444291990205, "Recalled product administered ": 29.230659891431067, "Red blood cell spherocytes present ": 457.6094814714768, "Respiratory distress ": 3.1672357157867705, "Respiratory rate increased ": 14.94566009596618, "Respiratory tract infection ": 2.1777443726492742, "Reticulocyte count increased ": 31.6345372472868, "SARS-CoV-2 antibody test positive ": 33.18082922987183, "Skin exfoliation ": 3.0262722299271774, "Skin reaction ": 2.6762542278622803, "Staphylococcal infection ": 3.5151275950197425, "Suspected transmission of an infectious agent via product ": 114.08575290454652, "Tachycardia ": 4.281118009858298, "Tachypnoea ": 12.14327144564711, "Therapy interrupted ": 4.822116494087546, "Throat tightness ": 3.108604274761102, "Toxic skin eruption ": 3.270143808704567, "Transfusion reaction ": 78.3204035106524, "Transfusion-associated dyspnoea ": 251.85200613890905, "Transfusion-related acute lung injury ": 120.33302668953164, "Transfusion-related circulatory overload ": 97.09580515036446, "Troponin increased ": 2.336208483320606, "Unevaluable event ": 2.044782742019027, "Urticaria ": 2.7677502414577764, "Vomiting ": 2.203392437805078, "Wheezing ": 3.193760137988662}
\ No newline at end of file
+{"Activated partial thromboplastin time prolonged": 38.83887178682311, "Acute kidney injury": 3.549487394962596, "Anticoagulation drug level increased": 1055.8045558201163, "Cardiac arrest": 4.893297045316147, "Cardiac failure": 2.7969427464486176, "Cardio-respiratory arrest": 5.181493971611359, "Cerebral haemorrhage": 26.30702910336432, "Cerebral infarction": 9.949272502517452, "Cerebrovascular accident": 3.7346920543148032, "Coagulopathy": 26.50508909634756, "Death": 11.061784302431493, "Gastrointestinal haemorrhage": 16.882217703784267, "General physical health deterioration": 2.672000515512168, "Haematuria": 6.530516502713406, "Haemoglobin decreased": 3.149704181373004, "Haemorrhage": 22.571761085566408, "Haemorrhage intracranial": 66.54078888492823, "Haemorrhagic transformation stroke": 384.43779001517566, "Ischaemic stroke": 24.57065142055085, "Melaena": 9.13755565258955, "Multiple organ dysfunction syndrome": 20.3051244338344, "Pneumonia": 2.6466164708829947, "Pulmonary embolism": 3.630379172301986, "Renal failure": 2.3720935026661145, "Respiratory failure": 4.29714759175005, "Sepsis": 7.372706732497508, "Septic shock": 19.5186778324819, "Shock": 9.637777716063638, "Shock haemorrhagic": 42.25465395635633}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/888.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/888.json
index e86ba14aef0..48b25b5fff8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/888.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/888.json
@@ -1 +1 @@
-{"Acute kidney injury ": 5.955999933908505, "Bradycardia ": 20.307188511289677, "Cardiac arrest ": 6.443030353386238, "Drug interaction ": 6.561795014140572, "Hyperkalaemia ": 11.59852231678672, "Hypokalaemia ": 6.001550414634785, "Hypotension ": 3.2044070428917637, "Syncope ": 3.134605532039512}
\ No newline at end of file
+{"Accidental death": 18.4778501981995, "Accidental overdose": 11.207150682832106, "Acute pulmonary oedema": 2.916422800370386, "Aggression": 4.570798691404058, "Agitation": 3.613703456328121, "Alcohol abuse": 11.496418322789271, "Alcohol poisoning": 19.271824525503582, "Altered state of consciousness": 3.466503339746278, "Anger": 3.960693525807887, "Anorgasmia": 11.797632611204277, "Arteriosclerosis": 3.525741811301765, "Arteriosclerosis coronary artery": 3.750352120746581, "Asphyxia": 2.827547709636631, "Aspiration": 4.661003713717296, "Bacterial infection": 3.1609669384792114, "Balance disorder": 2.016345613501756, "Behaviour disorder": 3.812427789585103, "Bradyphrenia": 2.9469187098456597, "Bradypnoea": 27.175871509933792, "Brain injury": 6.064269605999365, "Breath sounds abnormal": 8.57011599054879, "Cardiac arrest": 5.001921069653288, "Cardio-respiratory arrest": 4.429123799325488, "Cholestasis": 2.75280025488788, "Chronic sinusitis": 31.475393162468443, "Cognitive disorder": 3.0937776508794435, "Colitis": 7.960062766123682, "Colitis ulcerative": 8.455248989823694, "Coma": 9.463178255625737, "Coma scale abnormal": 19.351675561862734, "Completed suicide": 8.074405483357808, "Constipation": 3.4934491670363563, "Cutaneous vasculitis": 4.224032468053808, "Delirium": 2.4139822123802035, "Dependence": 4.94861756493467, "Depressed level of consciousness": 7.871573293311727, "Disturbance in attention": 2.509061463998855, "Drug abuse": 18.791472966754554, "Drug dependence": 6.743504180195513, "Drug diversion": 8.117969408865223, "Drug effect less than expected": 8.085496973990145, "Drug ineffective for unapproved indication": 2.566576635416982, "Drug interaction": 3.166144837849592, "Drug level increased": 4.920057784010582, "Drug use disorder": 22.504109193283664, "Dysarthria": 4.997138654675177, "Dyskinesia": 2.746480236270974, "Dyspepsia": 3.774885574734435, "Encephalopathy": 2.890087745507574, "Eosinophilia": 5.759221105372885, "Fall": 2.1878364157046484, "Feeling drunk": 3.0867872058919037, "Female genital tract fistula": 45.696109829174965, "Foaming at mouth": 23.05354771617104, "Frequent bowel movements": 16.269330528922094, "Full blood count abnormal": 3.672295055233335, "Haematochezia": 5.201559829857167, "Hallucination, visual": 2.580982864346789, "Hepatic cytolysis": 2.123286364691376, "Hepatic steatosis": 3.5751547801585506, "Hormone level abnormal": 3.2254840803075515, "Hypercapnia": 8.011447575436026, "Hypothermia": 2.250537572696859, "Hypovolaemia": 3.432068939865614, "Impaired driving ability": 3.145483563579853, "Inadequate analgesia": 16.664847894805806, "Infusion related reaction": 5.033343155396176, "Intentional overdose": 4.753450252466519, "Intentional product misuse": 7.811511987244406, "Intentional self-injury": 4.45371246951623, "Iron deficiency": 11.341693465278336, "Lip discolouration": 45.43554108321022, "Metabolic disorder": 4.534439873875772, "Middle insomnia": 10.016828619837776, "Miosis": 16.023784940724276, "Multiple sclerosis": 2.3585633878067807, "Muscle tightness": 3.42682494231502, "Mydriasis": 9.167445275691472, "Myoclonus": 6.5220207312007, "Nervous system disorder": 2.5221961149225134, "Obstructive airways disorder": 6.276656146265909, "Oral candidiasis": 17.077154894785256, "Overdose": 4.643060331804887, "Pallor": 2.026242357843714, "Paraesthesia oral": 7.500660612930214, "Parkinsonism": 4.152837257383991, "Pneumonia aspiration": 3.720507113663864, "Poisoning": 9.917735170604828, "Poisoning deliberate": 13.677759585299258, "Potentiating drug interaction": 8.949701258362044, "Prescription drug used without a prescription": 31.051901020905557, "Procedural pain": 28.24629973648908, "Proctitis": 39.93384210020158, "Product prescribing error": 5.00545959151239, "Productive cough": 2.976907677100928, "Radiculopathy": 35.468713699487, "Rectal haemorrhage": 6.6301361324604144, "Respiratory arrest": 8.65390308627428, "Respiratory depression": 12.98200079121052, "Rhabdomyolysis": 3.391803948352101, "Schizophrenia": 5.0948052972801126, "Sedation": 5.433182875904223, "Sedation complication": 4.50033922390486, "Sinus bradycardia": 6.614531249970632, "Skin ulcer": 2.6109820736009888, "Snoring": 28.17506337364058, "Somnolence": 3.571442768313641, "Substance abuse": 6.8057716548838965, "Substance use disorder": 7.872564141435303, "Suicide attempt": 2.678361402764402, "Suspected suicide": 9.27590936644401, "Therapeutic product effect incomplete": 6.293499168267745, "Tooth disorder": 4.288005965287804, "Tourette's disorder": 31.879971441794368, "Toxic encephalopathy": 3.9061073711505663, "Toxicity to various agents": 20.857228486778755, "Trigeminal neuralgia": 3.826842371479175, "Unresponsive to stimuli": 4.049212449418797, "Vaginal discharge": 25.06697748644396, "Vaginal flatulence": 54.24095847579364, "Withdrawal syndrome": 7.8924823094274945, "Wrong patient received product": 10.00994560728853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/889.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/889.json
index 27993e8ea74..58f04d454a2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/889.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/889.json
@@ -1 +1 @@
-{"Anxiety ": 2.999901777382809, "Arthritis ": 3.1474188356173176, "Autoimmune disorder ": 9.30614159252814, "Back pain ": 2.1297964786699315, "Blood parathyroid hormone increased ": 80.47040917665356, "Blood pressure increased ": 5.105591455729214, "Bone pain ": 2.833537344080409, "Dysuria ": 6.945468874700508, "Fall ": 2.3512809644354324, "Femur fracture ": 15.044543227503732, "Hypocalcaemia ": 44.18413924393011, "Hyponatraemia ": 7.665441288249248, "Impaired healing ": 7.726653681938115, "Jaundice ": 3.6114092421598, "Nervousness ": 4.0959464766758495, "Osteoarthritis ": 5.216499118007124, "Osteonecrosis of jaw ": 24.149922892268723, "Sleep disorder ": 2.791366773875038, "Urinary tract infection ": 2.6287628060295765, "Weight decreased ": 2.3125827648970656}
\ No newline at end of file
+{"Blood alkaline phosphatase increased": 23.79542210462477, "Blood calcium increased": 121.49477305195362, "Decreased appetite": 2.297148457924558, "Hypercalcaemia": 273.23643781903644, "Nausea": 2.5397712807688992, "Palpitations": 3.195143846090982, "Spinal fracture": 50.47369314178402, "Weight decreased": 5.452312202527639}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/89.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/89.json
index e4c068f027b..63114b5d6bb 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/89.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/89.json
@@ -1 +1 @@
-{"Drug ineffective ": 6.068142641212956}
\ No newline at end of file
+{"Completed suicide": 27.09054077122279, "Toxicity to various agents": 16.618445591439382}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/890.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/890.json
index d9ba06e1966..cb4582e18df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/890.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/890.json
@@ -1 +1 @@
-{"Abscess ": 5.575513494058053, "Accidental overdose ": 2.432886351274688, "Akathisia ": 6.113084100920687, "Altered state of consciousness ": 3.2260480695283427, "Atrioventricular block ": 5.165848409677793, "Blood pressure systolic decreased ": 13.284823948958318, "Blood thyroid stimulating hormone decreased ": 23.36938272372601, "Blood thyroid stimulating hormone increased ": 6.588234851312154, "Bradycardia ": 13.260995512949169, "Brain injury ": 12.312592760274702, "Bronchospasm ": 2.311209061697214, "Cardiac arrest ": 8.977884804593621, "Cardiogenic shock ": 14.078627837631007, "Circulatory collapse ": 6.763115915249816, "Cognitive disorder ": 2.561115769944391, "Coma ": 2.737417437053067, "Coma scale abnormal ": 19.668026446767044, "Completed suicide ": 11.475009151590369, "Cyanosis ": 2.687263086803661, "Depressed level of consciousness ": 2.35175437552844, "Drug ineffective ": 2.289900385943956, "Drug ineffective for unapproved indication ": 7.692739741913924, "Drug interaction ": 3.0612262287633145, "Drug intolerance ": 5.724773180912592, "Electrocardiogram QRS complex prolonged ": 26.210702152659383, "Electrocardiogram QT prolonged ": 3.345589616807365, "Hallucination, auditory ": 3.7947746908639264, "Hallucination, visual ": 3.5535107060293467, "Heart rate decreased ": 12.29596888045791, "Hepatotoxicity ": 2.061598014643246, "Hyperbilirubinaemia ": 5.243791039753565, "Hypertensive crisis ": 3.60636810340947, "Hyperthyroidism ": 4.21090021097424, "Hypotension ": 5.327060950096235, "Injection site haemorrhage ": 4.057152667527798, "Intentional overdose ": 6.065148853864478, "Metabolic acidosis ": 2.14146044815562, "Needle issue ": 8.186647474042685, "Nephrolithiasis ": 4.073491528838657, "Off label use ": 2.630831295717047, "Orthostatic hypotension ": 4.982558105281111, "Overdose ": 4.717267316909693, "Parkinsonism ": 5.280013938476501, "Peripheral coldness ": 3.4220670752125355, "Product administered to patient of inappropriate age ": 6.425338342645916, "Product use in unapproved indication ": 4.1496669766092005, "Product use issue ": 2.8519503884009936, "Respiratory arrest ": 11.088074381501512, "Restlessness ": 2.4401839366910543, "Rhabdomyolysis ": 2.1042276538279827, "Sedation ": 2.463916527713876, "Shock ": 4.230459410069172, "Sinus bradycardia ": 7.984507151868709, "Sleep apnoea syndrome ": 5.151297364672861, "Stress ": 2.390426165053328, "Temperature intolerance ": 8.750522323980825, "Therapeutic response decreased ": 3.0145779116792286, "Torsade de pointes ": 5.562997034987509, "Toxicity to various agents ": 5.724654221004366, "Treatment failure ": 2.139987627952955, "Unresponsive to stimuli ": 6.760882583586129, "Ventricular fibrillation ": 5.5355374065443606, "Ventricular tachycardia ": 3.264167633605167}
\ No newline at end of file
+{"Alanine aminotransferase increased": 19.842860680126417, "Aspartate aminotransferase increased": 20.78805621349088, "Electrocardiogram QT prolonged": 22.08900263208421}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/891.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/891.json
index 171105e02f5..f32dd261d80 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/891.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/891.json
@@ -1 +1 @@
-{"Autism spectrum disorder ": 110.610637420402, "Decreased appetite ": 2.8295821586983263, "Febrile convulsion ": 81.93010160442066, "Hyperpyrexia ": 29.4796726585562, "Overdose ": 6.098810933662947, "Pyrexia ": 3.7668342600306266, "Rash ": 4.255228364765522, "Seizure ": 2.855645143826055, "Wrong product administered ": 42.33311135124024}
\ No newline at end of file
+{"Abnormal behaviour": 2.028533872098258, "Allergy to metals": 103.3298867341244, "Anaphylactic reaction": 2.667811989453111, "Apathy": 3.409385977695288, "Apnoea": 19.557334292200004, "Autism spectrum disorder": 28.40843170151181, "Cardio-respiratory arrest": 2.116104001398313, "Choking": 3.4351448641797337, "Conjunctivitis": 5.453063070562339, "Crying": 30.84094324764328, "Cyanosis": 14.627333361385306, "Decreased appetite": 2.093352955558124, "Developmental delay": 8.439592604134354, "Dyskinesia": 2.686329215387332, "Eczema": 2.9614984590522613, "Erythema": 2.3591286669377376, "Erythema multiforme": 3.518161129250095, "Eye movement disorder": 6.291801470622841, "Febrile convulsion": 58.558532363690425, "Flatulence": 2.6112599940545307, "Gastroenteritis": 5.914651032696907, "Gastroenteritis rotavirus": 28.9951664818706, "Gaze palsy": 32.192489975390544, "Guillain-Barre syndrome": 4.56651240347074, "Haematochezia": 13.067908799921048, "Hyperpyrexia": 9.040335632377165, "Hyporesponsive to stimuli": 33.28122562400783, "Hypotonia": 13.198776932099891, "Hypotonic-hyporesponsive episode": 61.23766732362881, "Immune thrombocytopenia": 25.744990034558345, "Immunisation reaction": 2.1857287560268137, "Infantile vomiting": 191.88067974129405, "Intussusception": 219.5863100007606, "Irritability": 9.270499536555484, "Irritability postvaccinal": 28.962621222091308, "Kawasaki's disease": 157.09340249396317, "Local reaction": 4.131964970962158, "Measles": 23.48731622613252, "Mood altered": 6.940104640211494, "Mucous stools": 16.397799391602057, "Otitis media": 17.943591921436607, "Pallor": 15.10468510102677, "Petechiae": 9.995375776545409, "Pharyngitis": 4.405390526535821, "Presyncope": 2.008337150016915, "Product administered to patient of inappropriate age": 11.76949827751537, "Purpura": 6.652964799963264, "Pyrexia": 3.475026737035253, "Rash": 2.021959363462614, "Rash macular": 3.7780160519741854, "Rash maculo-papular": 2.489793804798778, "Rash morbilliform": 10.67803554030242, "Reaction to excipient": 27.348134156084345, "Respiratory arrest": 3.912567626387817, "Restlessness": 8.421711360481714, "Rhinorrhoea": 5.3202770547123865, "Scratch": 19.608899318377503, "Screaming": 33.50956357419441, "Seizure": 3.886293313008951, "Skin wound": 46.69086228118645, "Speech disorder developmental": 20.675862585465403, "Staring": 17.559643324297365, "Sudden death": 4.542776908942881, "Sudden infant death syndrome": 93.14758178177584, "Thrombocytopenic purpura": 44.67837880908317, "Unresponsive to stimuli": 6.607538015230865, "Upper respiratory tract infection": 3.994174102787701, "Urticaria": 2.1140733241702736, "Vaccination complication": 59.30392124658279, "Vaccination site erythema": 3.678785122755304, "Vaccination site granuloma": 114.03315106091456, "Vaccination site hypertrichosis": 341.6062232579544, "Vaccination site induration": 7.050810175884354, "Vaccination site pruritus": 4.198938032368928, "Vaccination site reaction": 2.2657043746261927, "Vaccination site swelling": 2.9137835919171184, "Viral infection": 10.483410532892169}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/892.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/892.json
index 32b78a14011..02b936c42f1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/892.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/892.json
@@ -1 +1 @@
-{"Blood glucose increased ": 38.649599433919406, "Drug ineffective ": 2.90036253273762, "Exposure during pregnancy ": 6.949151152162469, "Hyperglycaemia ": 13.65645944061656, "Hypersensitivity ": 4.761783734351623, "Hypoglycaemia ": 39.817111793820665, "Hypoglycaemic coma ": 52.756719255320775, "Liquid product physical issue ": 269.42646882059927, "Maternal exposure during pregnancy ": 12.127560380236863}
\ No newline at end of file
+{"Abdominal pain": 2.1924191014279493, "Acute kidney injury": 2.3436097849343023, "Drug interaction": 5.520842174979796, "Exposure during pregnancy": 10.666659023449665, "Hepatic enzyme increased": 6.63038261211724, "Immune reconstitution inflammatory syndrome": 115.58123582248996, "Rash": 2.618819417345023, "Rash maculo-papular": 8.311663762314943}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/893.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/893.json
index 65f3bb5cea8..6060936be16 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/893.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/893.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 3.333100499717094, "Amnesia ": 5.049670818159369, "Angioedema ": 2.879188159190186, "Aspartate aminotransferase increased ": 2.3873011206980417, "Blood alkaline phosphatase increased ": 5.092025947720859, "Blood creatine phosphokinase increased ": 3.1172410031194104, "Blood lactate dehydrogenase increased ": 4.881780841508879, "Blood pressure increased ": 2.3575046156835926, "Bone pain ": 2.520865924539914, "C-reactive protein increased ": 6.220816402775791, "Deep vein thrombosis ": 18.976521298233443, "Dermatitis bullous ": 7.295777580713275, "Disorientation ": 2.5225128899865514, "Drug eruption ": 2.601705222846117, "Drug reaction with eosinophilia and systemic symptoms ": 27.718946716368777, "Dysphagia ": 2.206685222059099, "Eczema ": 5.914249164916635, "Embolism ": 10.693648234357148, "Eosinophilia ": 19.64351038865956, "Epilepsy ": 2.3252081227075263, "Erythema multiforme ": 7.267953419498085, "Face oedema ": 4.124734742946936, "Gamma-glutamyltransferase increased ": 5.077490286593045, "Hepatic cytolysis ": 3.4730874065387947, "Memory impairment ": 2.632380138363757, "Mouth ulceration ": 9.7200562044117, "Muscle spasms ": 2.08928280948712, "Oedema peripheral ": 3.442064461322108, "Phlebitis ": 27.176896564318834, "Phlebitis deep ": 1201.3054046318136, "Pruritus ": 2.247697517951451, "Pulmonary embolism ": 14.161009928520787, "Rash erythematous ": 2.204201313957307, "Rash maculo-papular ": 5.211904806447, "Rash pruritic ": 6.026591782276786, "Stevens-Johnson syndrome ": 2.2426525988984025, "Stomatitis ": 2.634610828716776, "Superficial vein thrombosis ": 19.09748379497525, "Swollen tongue ": 4.309605731693081, "Toxic skin eruption ": 18.457914364249497, "Transaminases increased ": 3.285658328164603, "Transient ischaemic attack ": 3.058145567068717, "Urinary tract infection ": 2.8028240111661478, "White blood cell count increased ": 6.890425586572335}
\ No newline at end of file
+{"Anxiety": 2.998800227940469, "Blood pressure increased": 2.002602232825791, "Cardiac arrest": 6.58525693726546, "Chest X-ray abnormal": 105.50992778025244, "Confusional state": 4.004864637665608, "Drug withdrawal syndrome": 24.6190452188728, "Feeling abnormal": 3.386227643363722, "Hallucination": 9.680678579928584, "Loss of consciousness": 6.701512220572638, "Memory impairment": 4.426920092772397, "Mental status changes": 19.506438340585365, "Off label use": 3.005829304330519, "Overdose": 8.329305050587235, "Pain": 2.6517964624953985, "Respiratory failure": 9.2616198754291, "Sinus bradycardia": 44.4033289509607, "Unresponsive to stimuli": 30.153420442899247, "Urinary tract infection": 6.586118734352913, "Withdrawal syndrome": 15.497529369547182}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/894.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/894.json
index 4e69d67ffed..1434b68701d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/894.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/894.json
@@ -1 +1 @@
-{"Blister ": 4.314045402314704, "Cataract ": 13.546145947990938, "Dermatitis atopic ": 111.80989377603584, "Dyspepsia ": 8.132382769483337, "Dysphagia ": 6.867196944186953, "Eczema ": 8.863869691351558, "Eczema herpeticum ": 434.2928380819413, "Erythema ": 4.520548656148551, "Gastroenteritis ": 38.22338975982975, "Insomnia ": 2.8210568535750125, "Product use in unapproved indication ": 2.49080844340624, "Pruritus ": 2.9055277322336104, "Skin atrophy ": 93.01369960056503, "Skin burning sensation ": 26.887187989209444, "Skin discolouration ": 9.592735169271606, "Skin exfoliation ": 12.041146880655416, "Steroid withdrawal syndrome ": 423.2148123488931, "Topical steroid withdrawal reaction ": 769.574491164585}
\ No newline at end of file
+{"Alopecia": 24.917605499852616, "Drug ineffective": 5.444489129504986, "Pruritus": 8.921012458168759}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/895.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/895.json
index 9e26dfeeb6e..7a708f8a573 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/895.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/895.json
@@ -1 +1 @@
-{}
\ No newline at end of file
+{"Acute kidney injury": 8.015651642333145, "Angioedema": 6.576439548123348, "Blood pressure increased": 4.776081237401405, "Hyperkalaemia": 10.576431740740498, "Hypertension": 2.591248407823924, "Hyponatraemia": 6.851189071467454, "Hypotension": 8.082527899647715, "Lactic acidosis": 11.059916099594156, "Syncope": 5.539236917545549, "Therapy non-responder": 13.037516758579336, "Urinary retention": 8.228538927804658}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/896.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/896.json
index 0029e5c9e6e..0c288944c5c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/896.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/896.json
@@ -1 +1 @@
-{"Drug abuse ": 113.0037911801918, "Feeling of relaxation ": 6189.007009624309}
\ No newline at end of file
+{"Acute kidney injury": 5.06486137229661, "Hypokalaemia": 15.130603851658217, "Hyponatraemia": 43.86941329753903, "Hypotension": 12.777958137736794, "Orthostatic hypotension": 80.76180426002009, "Presyncope": 15.515070674962002, "Syncope": 5.122502323366779}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/897.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/897.json
index e3f0d6eb500..9af4c4f6c24 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/897.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/897.json
@@ -1 +1 @@
-{"Abdominal distension ": 19.11235954591917, "Abdominal pain ": 3.6909625922952514, "Abortion spontaneous ": 271.38723846364684, "Ascites ": 12.860592918138916, "Ectopic pregnancy ": 228.98950167502068, "Incorrect dose administered ": 21.50022029979359, "Off label use ": 18.135872092355264, "Ovarian hyperstimulation syndrome ": 1145.3262440447318}
\ No newline at end of file
+{"Acute pulmonary oedema": 6.181761857393153, "Allergic transfusion reaction": 272.8072824683236, "Anaphylactic reaction": 3.960165509990711, "Anaphylactoid reaction": 3.169751808219294, "Anti A antibody positive": 410.9592757351694, "Anti-erythrocyte antibody": 319.4621010732637, "Anti-erythrocyte antibody positive": 729.7952524802394, "Autoimmune haemolytic anaemia": 3.66211384624402, "Back pain": 2.6346347125007274, "Bacteraemia": 7.267599058867218, "Blood lactate dehydrogenase increased": 3.3069831974813115, "Blood pressure decreased": 2.0287379152652063, "Blood pressure increased": 2.721117749434925, "Body temperature increased": 3.78874790369147, "Bronchospasm": 4.147359201294235, "Chills": 3.0138003943397105, "Chromaturia": 2.6218448434477493, "Chronic inflammatory demyelinating polyradiculoneuropathy": 29.2352067001578, "Coombs direct test positive": 210.2039263971237, "Cyanosis": 4.116004096684859, "Delayed haemolytic transfusion reaction": 495.4914508169246, "Dermatitis allergic": 3.2309701505256028, "Dermatitis exfoliative generalised": 2.019778522512849, "Device related infection": 2.9931282403218487, "Drug ineffective for unapproved indication": 5.12365371278309, "Dyshidrotic eczema": 26.650163352733674, "Dyspnoea": 2.067044839911289, "Eczema": 4.763348387309782, "Extravasation": 12.782158107584708, "Febrile nonhaemolytic transfusion reaction": 317.6474411273187, "Feeling cold": 2.4748199754276072, "Flank pain": 3.1266282212611496, "Flushing": 5.947112184775699, "Gynaecomastia": 3.7078464164328473, "Haemoglobin decreased": 4.918648054403541, "Haemoglobinuria": 53.52160665306746, "Haemolysis": 61.13158230321904, "Haemolytic anaemia": 31.198500925407465, "Haptoglobin decreased": 36.92356423182349, "Heart rate increased": 2.195091643601432, "Hepatitis B": 10.449094457891476, "Hepatitis B core antibody positive": 208.7809434457605, "Hepatitis B surface antibody positive": 194.94456465112216, "Hyper IgE syndrome": 898.8870729328216, "Hyperpyrexia": 2.027474039395833, "Hypersensitivity": 2.933236042631534, "Hypertension": 3.200989353988311, "Hyperthermia": 7.6045744899097505, "Hypervolaemia": 5.632508870372009, "Hypotension": 2.6348478342240127, "Hypothermia": 2.375798491582636, "Hypoxia": 7.529499409246243, "Incorrect drug administration rate": 37.94492432989593, "Infusion related reaction": 4.273712880470028, "Infusion site erythema": 7.781073874128937, "Infusion site extravasation": 13.5764120125042, "Infusion site swelling": 8.978221153586317, "Intravascular haemolysis": 39.97493580988354, "Livedo reticularis": 19.031622473343152, "Lung infiltration": 2.659002016273301, "Meningeal disorder": 51.809006245977095, "Meningism": 43.20889455758225, "Meningitis": 6.603147610579945, "Meningitis aseptic": 180.84566839423408, "Musculoskeletal stiffness": 3.05722169811933, "Myasthenia gravis": 2.5112297046233496, "Neck pain": 2.1928169217371267, "No adverse event": 43.0628687564604, "Nuchal rigidity": 22.83840439617604, "Oxygen saturation decreased": 8.893965734234989, "Pallor": 2.6521102559687644, "Phonophobia": 25.70397190639976, "Photophobia": 9.29144868480372, "Pneumonia staphylococcal": 23.696515497988905, "Product use in unapproved indication": 2.2914307750418583, "Pulmonary embolism": 2.0141189510843738, "Rash pruritic": 2.101415566064132, "Recalled product administered": 29.219136501435766, "Red blood cell spherocytes present": 457.4290938374648, "Respiratory distress": 3.165986977974786, "Respiratory rate increased": 14.939767562216788, "Respiratory tract infection": 2.176885876082865, "Reticulocyte count increased": 31.62206682594228, "SARS-CoV-2 antibody test positive": 33.16774962029323, "Skin exfoliation": 3.0250790818081814, "Skin reaction": 2.6751991634570254, "Staphylococcal infection": 3.51374180147719, "Suspected transmission of an infectious agent via product": 114.04077315802948, "Tachycardia": 4.279320733252296, "Tachypnoea": 12.136740230264456, "Therapy interrupted": 4.820215539929466, "Throat tightness": 3.1073787022919803, "Toxic skin eruption": 3.268854620317949, "Transfusion reaction": 78.28952849617232, "Transfusion-associated dyspnoea": 251.752729541161, "Transfusion-related acute lung injury": 120.28558772999926, "Transfusion-related circulatory overload": 97.05753103994792, "Troponin increased": 2.335287552624162, "Unevaluable event": 2.043976647513423, "Urticaria": 2.766630145047806, "Vomiting": 2.202493367062089, "Wheezing": 3.1923735447008026}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/898.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/898.json
index 3129950f928..402bb1502d8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/898.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/898.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.6685143224020207, "Accommodation disorder ": 114.14679605699676, "Alanine aminotransferase abnormal ": 137.8004464089082, "Alanine aminotransferase increased ": 2.9143306912352585, "Aspartate aminotransferase abnormal ": 262.8945304909362, "Bronchospasm ": 6.616126976354259, "Capillary leak syndrome ": 746.5600635311396, "Cough ": 3.2026061116302587, "Cytokine release syndrome ": 12.1959651985146, "Device related bacteraemia ": 3928.132134634512, "Disease progression ": 7.685486487787779, "Hypersensitivity ": 3.5653160292202, "Hypotension ": 3.4022050815188187, "Hypoxia ": 7.0618813113374905, "Malignant neoplasm progression ": 8.80731004006506, "Mydriasis ": 35.60914388603176, "Neuroblastoma recurrent ": 2551.4870964439315, "Neuropathy peripheral ": 3.0461581070674213, "Oedema ": 3.238606306832298, "Off label use ": 3.59910091199532, "Oxygen saturation decreased ": 3.4826469525089703, "Pain ": 5.133261962339349, "Pyrexia ": 3.125879337599676, "Respiratory failure ": 4.8984031427509445, "Sepsis ": 2.0487947394874086, "Tachycardia ": 4.493348216861191, "Toxicity to various agents ": 2.0772291995017844, "Urinary retention ": 7.054956469212461}
\ No newline at end of file
+{"Acute kidney injury": 5.955999933908505, "Bradycardia": 20.30655186806892, "Cardiac arrest": 6.443030353386238, "Drug interaction": 6.561795014140572, "Hyperkalaemia": 11.596923223729227, "Hypokalaemia": 6.001550414634785, "Hypotension": 3.204332967713845, "Syncope": 3.1345623951207644}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/899.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/899.json
index 6d1267e5e61..3cb8850d082 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/899.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/899.json
@@ -1 +1 @@
-{"Off label use ": 4.883360417129567}
\ No newline at end of file
+{"Anxiety": 2.999901777382809, "Arthritis": 3.1474188356173176, "Autoimmune disorder": 9.30614159252814, "Back pain": 2.1297964786699315, "Blood parathyroid hormone increased": 80.47040917665356, "Blood pressure increased": 5.105501815139136, "Bone pain": 2.833537344080409, "Dysuria": 6.945468874700508, "Fall": 2.3512206860908784, "Femur fracture": 15.044543227503732, "Hypocalcaemia": 44.18413924393011, "Hyponatraemia": 7.665441288249248, "Impaired healing": 7.726653681938115, "Jaundice": 3.6114092421598, "Nervousness": 4.0959464766758495, "Osteoarthritis": 5.216499118007124, "Osteonecrosis of jaw": 24.149922892268723, "Sleep disorder": 2.791366773875038, "Urinary tract infection": 2.6287628060295765, "Weight decreased": 2.3125827648970656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/9.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/9.json
index 973f1196589..85e644d90f9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/9.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/9.json
@@ -1 +1 @@
-{"Emotional distress ": 161.85208465362794, "Hypersensitivity ": 70.04082379006084, "Injury ": 405.3413816831731}
\ No newline at end of file
+{"Acute coronary syndrome": 98.12491820156411, "Acute kidney injury": 7.839449914233081, "Disease progression": 19.19293996840077, "Drug interaction": 2.729721991634752, "Hepatotoxicity": 27.09826907391346, "Hormone-refractory prostate cancer": 497.7202871067497, "Hypokalaemia": 9.00798235062046, "Malignant neoplasm progression": 9.80531146295762, "Prostate cancer metastatic": 758.3802573695656, "Rhabdomyolysis": 27.94208360278053}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/90.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/90.json
index d04d1f1e71e..cfb62a6e3c5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/90.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/90.json
@@ -1 +1 @@
-{"Cardio-respiratory arrest ": 28.557408124964653, "Completed suicide ": 24.51375262499884, "Overdose ": 9.465665925996325}
\ No newline at end of file
+{"Completed suicide": 10.70798892837862, "Drug dependence": 17.39829051045501, "Overdose": 7.557112045353668, "Substance abuse": 90.91997633762354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/900.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/900.json
index 44caa871e50..b8e3a2cc5fd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/900.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/900.json
@@ -1 +1 @@
-{"Accidental exposure to product ": 15.709376464122007, "Adverse event ": 2.314865840083234, "Allodynia ": 49.4717389225508, "Application site burn ": 451.2862945158739, "Application site discolouration ": 82.97038620744593, "Application site erythema ": 225.33352477841436, "Application site hyperaesthesia ": 4101.869131213314, "Application site inflammation ": 70.4415342237246, "Application site oedema ": 252.8061759506137, "Application site pain ": 155.62902365216024, "Application site paraesthesia ": 85.15413995213785, "Application site pruritus ": 79.07628640548619, "Application site reaction ": 16.39090043961273, "Application site swelling ": 30.260150448059377, "Application site vesicles ": 592.120629817139, "Application site warmth ": 443.6786496626767, "Blister ": 6.566157019135596, "Burning sensation ": 29.231661017085308, "Burns first degree ": 484.92340337903954, "Burns second degree ": 607.7326657258338, "Complex regional pain syndrome ": 64.1071452450929, "Condition aggravated ": 2.0469474345988337, "Cough ": 2.783883650497767, "Erythema ": 5.389011072369196, "Eye irritation ": 24.07825256900238, "Eye pain ": 4.123300743251277, "Eye pruritus ": 4.7326865192753935, "Feeling hot ": 4.250103619096478, "Hyperaesthesia ": 7.613765454166288, "Hypersensitivity ": 2.39786380055675, "Inappropriate schedule of product administration ": 2.922072863967962, "Incorrect product administration duration ": 12.614906158993572, "Neuralgia ": 2.519298233887701, "Occupational exposure to product ": 1538.1797386052046, "Oral discomfort ": 4.59956394822805, "Pain ": 4.2188097595354535, "Presyncope ": 2.39788887399838, "Product administered at inappropriate site ": 43.80814975471984, "Product quality issue ": 4.776658249530487, "Product use issue ": 4.37876656700965, "Respiratory tract irritation ": 112.0339539867263, "Skin burning sensation ": 6.237275929931049, "Skin lesion ": 4.076096657856376, "Skin reaction ": 5.953423007477755, "Therapeutic product effect decreased ": 3.226998852160731, "Therapeutic product effect incomplete ": 2.425639602122521, "Thermal burn ": 69.85504554084534, "Throat irritation ": 23.15140497049723, "Wrong technique in product usage process ": 9.423568048248354}
\ No newline at end of file
+{"Abscess": 5.559588630152646, "Accidental overdose": 2.425937193683861, "Akathisia": 6.0956223297312, "Altered state of consciousness": 3.216831849858869, "Atrioventricular block": 5.151093636545982, "Blood pressure systolic decreased": 13.24687798513316, "Blood thyroid stimulating hormone decreased": 23.302630528282243, "Blood thyroid stimulating hormone increased": 6.56941743988233, "Bradycardia": 13.22265677960798, "Brain injury": 12.277419175542196, "Bronchospasm": 2.304607318354291, "Cardiac arrest": 8.952217778550065, "Cardiogenic shock": 14.03840097043482, "Circulatory collapse": 6.743792667818018, "Cognitive disorder": 2.553799766936692, "Coma": 2.7295967780985784, "Coma scale abnormal": 19.611845637474183, "Completed suicide": 11.442193017488036, "Cyanosis": 2.6790872841584306, "Depressed level of consciousness": 2.345035959234187, "Drug ineffective": 2.283332749835328, "Drug ineffective for unapproved indication": 7.670762000771435, "Drug interaction": 3.05247535307908, "Drug intolerance": 5.708409535390975, "Electrocardiogram QRS complex prolonged": 26.135827030316797, "Electrocardiogram QT prolonged": 3.336031442452793, "Hallucination, auditory": 3.7839357506232414, "Hallucination, visual": 3.543360050268616, "Heart rate decreased": 12.260831765631924, "Hepatotoxicity": 2.0557096456303454, "Hyperbilirubinaemia": 5.228812366552086, "Hypertensive crisis": 3.5960673049710707, "Hyperthyroidism": 4.198488588792926, "Hypotension": 5.311702892817073, "Injection site haemorrhage": 4.045564566223877, "Intentional overdose": 6.047812754570971, "Metabolic acidosis": 2.135343835668253, "Needle issue": 8.163264125890032, "Nephrolithiasis": 4.06118259717249, "Off label use": 2.623203777941737, "Orthostatic hypotension": 4.9672540699881065, "Overdose": 4.703782006492072, "Parkinsonism": 5.264932741200411, "Peripheral coldness": 3.412292079338455, "Product administered to patient of inappropriate age": 6.406986198235708, "Product use in unapproved indication": 4.137674720414078, "Product use issue": 2.843800988497428, "Respiratory arrest": 11.056388594375356, "Restlessness": 2.4330846415611385, "Rhabdomyolysis": 2.0982165674416087, "Sedation": 2.45687905049138, "Shock": 4.218374595369353, "Sinus bradycardia": 7.961699301909221, "Sleep apnoea syndrome": 5.134308098719594, "Stress": 2.3835981458431625, "Temperature intolerance": 8.725528961993163, "Therapeutic response decreased": 3.0059664069691867, "Torsade de pointes": 5.547107213906486, "Toxicity to various agents": 5.70828544843191, "Treatment failure": 2.133874179921614, "Unresponsive to stimuli": 6.740824789672109, "Ventricular fibrillation": 5.519725372420459, "Ventricular tachycardia": 3.2548440525605367}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/901.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/901.json
index 3a06c990134..2d27f2c02df 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/901.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/901.json
@@ -1 +1 @@
-{"Acute promyelocytic leukaemia ": 1435.2248209618683, "Dehydration ": 6.001727146308595, "Disease progression ": 6.847177552873984, "Dysphagia ": 6.5225254836408695, "Interstitial lung disease ": 2.367174071577374, "Leukopenia ": 5.927868342492429, "Mucosal inflammation ": 20.097733810354235, "Neutropenia ": 3.759333957557211, "Oedema ": 3.7102596845300617, "Pancytopenia ": 4.530630819096461, "Sepsis ": 5.161862738354683, "Stevens-Johnson syndrome ": 5.863591174985291, "Thrombocytopenia ": 3.863958458920434, "Weight decreased ": 2.9366540026450085}
\ No newline at end of file
+{"Autism spectrum disorder": 110.57317315744714, "Decreased appetite": 2.829554714812977, "Febrile convulsion": 81.90154944381175, "Hyperpyrexia": 29.4796726585562, "Overdose": 6.098810933662947, "Pyrexia": 3.766753811276931, "Rash": 4.255169913914106, "Seizure": 2.8553286170712826, "Wrong product administered": 42.33311135124024}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/902.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/902.json
index c8279d64e9d..053a3882393 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/902.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/902.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 133.503888480076, "Disease progression ": 6.680034192039005, "Myelodysplastic syndrome ": 76.19645250821675}
\ No newline at end of file
+{"Blood glucose increased": 38.649599433919406, "Drug ineffective": 2.900341092767188, "Exposure during pregnancy": 6.949151152162469, "Hyperglycaemia": 13.65645944061656, "Hypersensitivity": 4.761783734351623, "Hypoglycaemia": 39.81576644763496, "Hypoglycaemic coma": 52.756719255320775, "Liquid product physical issue": 269.42646882059927, "Maternal exposure during pregnancy": 12.127560380236863}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/903.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/903.json
index e817070fef4..f035693c459 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/903.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/903.json
@@ -1 +1 @@
-{"Drug interaction ": 9.530118811960705, "Immune reconstitution inflammatory syndrome ": 165.08883489826445, "Psychiatric decompensation ": 663.2396778811935}
\ No newline at end of file
+{"Alanine aminotransferase increased": 3.333100499717094, "Amnesia": 5.049670818159369, "Angioedema": 2.879188159190186, "Aspartate aminotransferase increased": 2.3873011206980417, "Blood alkaline phosphatase increased": 5.092025947720859, "Blood creatine phosphokinase increased": 3.1172410031194104, "Blood lactate dehydrogenase increased": 4.881780841508879, "Blood pressure increased": 2.357463229497969, "Bone pain": 2.520865924539914, "C-reactive protein increased": 6.220816402775791, "Deep vein thrombosis": 18.976521298233443, "Dermatitis bullous": 7.295777580713275, "Disorientation": 2.5225128899865514, "Drug eruption": 2.601705222846117, "Drug reaction with eosinophilia and systemic symptoms": 27.71664721093901, "Dysphagia": 2.206685222059099, "Eczema": 5.914249164916635, "Embolism": 10.693648234357148, "Eosinophilia": 19.64351038865956, "Epilepsy": 2.3252081227075263, "Erythema multiforme": 7.267953419498085, "Face oedema": 4.124734742946936, "Gamma-glutamyltransferase increased": 5.077490286593045, "Hepatic cytolysis": 3.4730874065387947, "Memory impairment": 2.632380138363757, "Mouth ulceration": 9.7200562044117, "Muscle spasms": 2.08928280948712, "Oedema peripheral": 3.441979364181406, "Phlebitis": 27.176896564318834, "Phlebitis deep": 1201.3054046318136, "Pruritus": 2.2476702846426093, "Pulmonary embolism": 14.161009928520787, "Rash erythematous": 2.204201313957307, "Rash maculo-papular": 5.211904806447, "Rash pruritic": 6.026591782276786, "Stevens-Johnson syndrome": 2.2426525988984025, "Stomatitis": 2.634610828716776, "Superficial vein thrombosis": 19.09748379497525, "Swollen tongue": 4.309605731693081, "Toxic skin eruption": 18.457914364249497, "Transaminases increased": 3.2854570849290208, "Transient ischaemic attack": 3.058145567068717, "Urinary tract infection": 2.8028240111661478, "White blood cell count increased": 6.889105111042243}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/904.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/904.json
index 628e72b84d2..aa21b740d26 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/904.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/904.json
@@ -1 +1 @@
-{"Amnesia ": 3.06078726370813, "Angina pectoris ": 8.825517861269901, "Balance disorder ": 2.683423784712419, "Blood creatinine increased ": 2.1424472983394653, "Blood pressure decreased ": 2.9908112504184854, "Bradycardia ": 3.3454798236021865, "Cardiac failure ": 2.222919889838336, "Chromaturia ": 14.44729951282272, "Confusional state ": 2.508211412146361, "Constipation ": 8.068916833641287, "Disorientation ": 2.815224351009764, "Dizziness ": 4.163421604969596, "Drug interaction ": 3.80848408579945, "Dry mouth ": 5.052210979262974, "Dyspepsia ": 2.473764833965856, "Dysuria ": 2.742075923854959, "Electrocardiogram QT prolonged ": 5.54930487941373, "Flatulence ": 3.698313903196732, "Glomerular filtration rate decreased ": 6.02218835659011, "Hallucination ": 3.229017383635012, "Hallucination, visual ": 6.560073753302664, "Hyperhidrosis ": 2.028537912237953, "Hyponatraemia ": 4.21310433504435, "Hypotension ": 2.7633817851873403, "Labelled drug-drug interaction medication error ": 4.589921357920211, "Off label use ": 2.333976444094533, "Orthostatic hypotension ": 6.362263449420153, "Rhabdomyolysis ": 3.551616840388013, "Syncope ": 2.7894655454613, "Tinnitus ": 3.5800039582897085, "Torsade de pointes ": 12.64698954549783, "Underdose ": 7.858868622907402, "Ventricular tachycardia ": 6.273515621681442, "Vertigo ": 3.287332223961009, "Vision blurred ": 4.3750695015231225, "Visual impairment ": 2.260566440901425, "Wrong technique in product usage process ": 3.366464162472266}
\ No newline at end of file
+{"Blister": 4.306847454028175, "Cataract": 13.523531574228867, "Dermatitis atopic": 111.62323705997188, "Dyspepsia": 8.118803563302274, "Dysphagia": 6.855731443215777, "Eczema": 8.849080407545403, "Eczema herpeticum": 433.5683513177272, "Erythema": 4.512947855039124, "Gastroenteritis": 38.15957859877299, "Insomnia": 2.8163463350684217, "Product use in unapproved indication": 2.486574018664101, "Pruritus": 2.9006352808946056, "Skin atrophy": 92.85848978278298, "Skin burning sensation": 26.842292689015668, "Skin discolouration": 9.576731816417473, "Skin exfoliation": 12.02104929625176, "Steroid withdrawal syndrome": 422.5084700847652, "Topical steroid withdrawal reaction": 768.2904198943397}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/905.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/905.json
index 1a5a8ee1d2c..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/905.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/905.json
@@ -1 +1 @@
-{"Cough ": 16.44471447742089, "Dyspnoea ": 7.711475812665724, "Lower respiratory tract infection ": 119.9638786744081}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/906.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/906.json
index ec78425e817..67e1553eba5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/906.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/906.json
@@ -1 +1 @@
-{"Angina pectoris ": 18.4296308397781, "Blood creatinine increased ": 2.227887020088801, "Cardiac arrest ": 3.9003529525993774, "Cardiac disorder ": 3.482669517586212, "Cardiac failure congestive ": 3.6445841185602887, "Cardiac operation ": 38.77372094667076, "Cardiac pacemaker insertion ": 30.689058500274395, "Cerebrovascular accident ": 3.826047687601473, "Chest pain ": 3.7942097068828007, "Chromaturia ": 7.140668111941144, "Completed suicide ": 2.134025833840385, "Constipation ": 3.7121878971298976, "Coronary arterial stent insertion ": 55.06700379693664, "Coronary artery disease ": 3.265290094761527, "Death ": 6.898066994844456, "Dementia ": 7.619257816376308, "Diabetes mellitus ": 4.661594047273731, "Dizziness ": 2.4691724897702443, "Drug interaction ": 5.185624994608356, "Electrocardiogram QT prolonged ": 14.392136698131354, "Fall ": 2.430871641668713, "Hallucination ": 5.94244126177556, "Hallucination, visual ": 5.168106004558706, "Heart rate decreased ": 5.70689113614341, "Hypoacusis ": 6.349896577988758, "Hypotension ": 2.2573809983849027, "Loss of consciousness ": 3.002422979862492, "Medication error ": 2.56687880833589, "Myocardial infarction ": 6.369605078928369, "Orthostatic hypotension ": 6.476262642330863, "Parkinson's disease ": 8.306014249681576, "Product residue present ": 16.90370673062155, "Renal impairment ": 2.603503655568425, "Rhabdomyolysis ": 4.685660491757384, "Stent placement ": 95.27640926373576, "Syncope ": 2.532811778438509, "Torsade de pointes ": 19.51608325145857, "Unevaluable event ": 12.18475737516159, "Urinary retention ": 4.446116108841981, "Ventricular fibrillation ": 8.780738603230352, "Ventricular tachycardia ": 12.108423842729298, "Wrong technique in product usage process ": 3.714944082924613}
\ No newline at end of file
+{"Drug abuse": 113.0037911801918, "Feeling of relaxation": 6189.007009624309}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/907.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/907.json
index 5702a68404c..8b570a5cdf3 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/907.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/907.json
@@ -1 +1 @@
-{"Acne ": 2.4842823850667592, "Aphthous ulcer ": 5.9926740554940325, "Ascites ": 2.000256793249996, "Blindness ": 2.9933731814769478, "Blood cholesterol increased ": 2.743195193501178, "Blood creatinine increased ": 4.45681864788023, "Blood triglycerides increased ": 4.762726277158749, "Body height decreased ": 6.121524703993062, "Cardiac disorder ": 2.206845174363937, "Cellulitis ": 2.474994073095889, "Cerebrovascular accident ": 2.4515180498800824, "Clostridium difficile infection ": 2.521642374968734, "Cytomegalovirus infection ": 6.987375344366411, "Deep vein thrombosis ": 2.814376747756138, "Dementia ": 2.856320574446203, "Diabetes mellitus ": 4.2154013296973, "Drug effective for unapproved indication ": 12.753466944716411, "Drug ineffective for unapproved indication ": 7.076652082996148, "Drug interaction ": 2.0279716493801816, "Drug level below therapeutic ": 15.167214969841057, "Drug level decreased ": 15.113397122277602, "Drug level increased ": 13.023604657935833, "End stage renal disease ": 2.7184021550693958, "Expired product administered ": 5.443644555469545, "Fluid retention ": 2.5186913686275254, "Graft versus host disease ": 14.836480259728772, "Haemolytic uraemic syndrome ": 82.5573018803982, "Heart transplant ": 109.08693549545588, "Heart transplant rejection ": 73.29288153381675, "Hernia ": 15.53870714872362, "Hip fracture ": 4.306724710695486, "Hyperlipidaemia ": 4.326524495775605, "Hypertriglyceridaemia ": 8.74494750542327, "Illness ": 3.262851459588308, "Immune system disorder ": 4.540348188406744, "Immunosuppressant drug level increased ": 77.82861309558291, "Impaired healing ": 7.3023644694553855, "Infection ": 3.43904112994251, "Interstitial lung disease ": 6.669387723052361, "Kidney transplant rejection ": 70.55575082485579, "Liver transplant ": 18.514104413007264, "Liver transplant rejection ": 63.632980704996754, "Localised infection ": 3.538862940170233, "Lower limb fracture ": 3.0883412065560827, "Lung disorder ": 4.837676975714129, "Lung infiltration ": 11.919951611047733, "Lung neoplasm malignant ": 3.047617199088322, "Lymphoedema ": 15.377927480648806, "Lymphoma ": 7.338574276139948, "Mouth ulceration ": 7.704345945818331, "Neoplasm malignant ": 4.103570283496334, "Nephrotic syndrome ": 6.088105424083695, "Oedema ": 2.9596863816580017, "Oedema peripheral ": 2.28412758020039, "Off label use ": 5.940305461987143, "Organising pneumonia ": 16.689030056545406, "Pericardial effusion ": 5.737647637189616, "Pleural effusion ": 2.033187845704041, "Pneumocystis jirovecii pneumonia ": 7.117993153674562, "Pneumonia ": 4.1466922448876495, "Pneumonitis ": 20.949903577099384, "Post transplant lymphoproliferative disorder ": 9.425074859114725, "Product dispensing error ": 3.1069162988031027, "Product prescribing error ": 10.131909055004488, "Product use in unapproved indication ": 15.25245291838434, "Product use issue ": 3.615909892377676, "Proteinuria ": 11.568118061452555, "Pulmonary fibrosis ": 5.7107614439992185, "Pulmonary haemorrhage ": 7.003058264287289, "Renal disorder ": 6.511692220731865, "Renal failure ": 2.783607583898177, "Renal impairment ": 3.100969733721466, "Renal tubular necrosis ": 6.262581113414199, "Respiratory failure ": 2.502904921061451, "Sepsis ": 3.52448506999831, "Skin cancer ": 26.048425817844425, "Skin ulcer ": 2.95520767189949, "Stomatitis ": 2.3711252314244207, "Thrombotic microangiopathy ": 17.715762209385286, "Transplant rejection ": 63.50580794521762, "Urinary tract infection ": 3.222906554590756, "Viral infection ": 2.90250774340575}
\ No newline at end of file
+{"Abdominal distension": 19.11235954591917, "Abdominal pain": 3.6909625922952514, "Abortion spontaneous": 271.38723846364684, "Ascites": 12.860592918138916, "Ectopic pregnancy": 228.98950167502068, "Incorrect dose administered": 21.50022029979359, "Off label use": 18.135157433257625, "Ovarian hyperstimulation syndrome": 1145.3262440447318}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/908.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/908.json
index 7dd25efecc1..d44e59cfba1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/908.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/908.json
@@ -1 +1 @@
-{"Cardiac arrest ": 12.686668756011954, "Cerebral haemorrhage ": 325.604758280221}
\ No newline at end of file
+{"Abdominal pain": 2.6685143224020207, "Accommodation disorder": 114.14679605699676, "Alanine aminotransferase abnormal": 137.8004464089082, "Alanine aminotransferase increased": 2.9143306912352585, "Aspartate aminotransferase abnormal": 262.8945304909362, "Bronchospasm": 6.616126976354259, "Capillary leak syndrome": 746.5600635311396, "Cough": 3.2025764026269163, "Cytokine release syndrome": 12.1959651985146, "Device related bacteraemia": 3928.132134634512, "Disease progression": 7.685486487787779, "Hypersensitivity": 3.5653160292202, "Hypotension": 3.4021264175996984, "Hypoxia": 7.0618813113374905, "Malignant neoplasm progression": 8.80731004006506, "Mydriasis": 35.60914388603176, "Neuroblastoma recurrent": 2551.4870964439315, "Neuropathy peripheral": 3.046065633013394, "Oedema": 3.238606306832298, "Off label use": 3.59895912671396, "Oxygen saturation decreased": 3.4824606360539043, "Pain": 5.133218313823777, "Pyrexia": 3.125812565257907, "Respiratory failure": 4.897998665940421, "Sepsis": 2.0487947394874086, "Tachycardia": 4.493234632674741, "Toxicity to various agents": 2.0772291995017844, "Urinary retention": 7.054956469212461}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/909.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/909.json
index 6472ba56f26..0748858e447 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/909.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/909.json
@@ -1 +1 @@
-{"Angina pectoris ": 9.12085758322994, "Atrioventricular block ": 57.79364215928979, "Atrioventricular block complete ": 50.46396821372571, "Blood pressure decreased ": 14.938304259971554, "Bradycardia ": 14.424446752245444, "Bronchospasm ": 24.44311556697105, "Cardiac arrest ": 27.998892804404505, "Chest discomfort ": 8.074860891370413, "Chest pain ": 2.6491982543369024, "Discomfort ": 19.64906753404985, "Dizziness ": 3.008945610127116, "Dyspnoea ": 4.027842570568169, "Heart rate decreased ": 22.20754325626869, "Heart rate increased ": 4.62292254968632, "Hypotension ": 8.68470687019341, "Incorrect product administration duration ": 28.680268685146057, "Loss of consciousness ": 2.5571452123022893, "Nausea ": 2.129869984020443, "Presyncope ": 4.7424936056094, "Sinus bradycardia ": 29.78775491236836, "Vomiting ": 2.4269932621366284}
\ No newline at end of file
+{"Off label use": 4.883168094327245}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/91.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/91.json
index c27d700a71d..4d88c97ade9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/91.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/91.json
@@ -1 +1 @@
-{"Asthma ": 5.792623423146339, "Blood pressure increased ": 5.199049149517635, "Chest discomfort ": 5.198410548048072, "Drug hypersensitivity ": 8.843767800274412, "Drug interaction ": 7.476289550973353, "Erectile dysfunction ": 30.072979219334247, "Hypertension ": 4.718602907149649, "Palpitations ": 3.6073794538208888, "Rash ": 2.092873464103183, "Throat tightness ": 36.33814622424957, "Urticaria ": 3.0349387013136786, "Wheezing ": 11.781719784092292}
\ No newline at end of file
+{"Drug ineffective": 6.0680977871556045}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/910.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/910.json
index e4c42bf6cb2..e1afc44f058 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/910.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/910.json
@@ -1 +1 @@
-{"Completed suicide ": 11.766182062559732, "Drug interaction ": 5.698655364636911, "Erectile dysfunction ": 41.3728581767196, "Impulse-control disorder ": 882.9245621992858, "Product use in unapproved indication ": 8.103199376948977, "Suicidal ideation ": 14.328539877611613, "Therapeutic product ineffective ": 305.2553639664196}
\ No newline at end of file
+{"Accidental exposure to product": 15.709376464122007, "Adverse event": 2.314865840083234, "Allodynia": 49.4717389225508, "Application site burn": 450.4875028600421, "Application site discolouration": 82.97038620744593, "Application site erythema": 225.29606416842825, "Application site hyperaesthesia": 4101.869131213314, "Application site inflammation": 70.4415342237246, "Application site oedema": 252.8061759506137, "Application site pain": 155.60998013993242, "Application site paraesthesia": 85.15413995213785, "Application site pruritus": 79.07628640548619, "Application site reaction": 16.39090043961273, "Application site swelling": 30.260150448059377, "Application site vesicles": 592.120629817139, "Application site warmth": 442.7458717345995, "Blister": 6.566157019135596, "Burning sensation": 29.231661017085308, "Burns first degree": 484.92340337903954, "Burns second degree": 607.7326657258338, "Complex regional pain syndrome": 64.1071452450929, "Condition aggravated": 2.0469474345988337, "Cough": 2.783857819523716, "Erythema": 5.388958317382199, "Eye irritation": 24.07825256900238, "Eye pain": 4.123300743251277, "Eye pruritus": 4.7326865192753935, "Feeling hot": 4.250103619096478, "Hyperaesthesia": 7.613765454166288, "Hypersensitivity": 2.39786380055675, "Inappropriate schedule of product administration": 2.922072863967962, "Incorrect product administration duration": 12.614906158993572, "Neuralgia": 2.519298233887701, "Occupational exposure to product": 1538.1797386052046, "Oral discomfort": 4.59956394822805, "Pain": 4.218773874802195, "Presyncope": 2.39788887399838, "Product administered at inappropriate site": 43.80814975471984, "Product quality issue": 4.776658249530487, "Product use issue": 4.37876656700965, "Respiratory tract irritation": 112.0339539867263, "Skin burning sensation": 6.237275929931049, "Skin lesion": 4.076096657856376, "Skin reaction": 5.953423007477755, "Therapeutic product effect decreased": 3.226998852160731, "Therapeutic product effect incomplete": 2.425639602122521, "Thermal burn": 69.85504554084534, "Throat irritation": 23.15140497049723, "Wrong technique in product usage process": 9.423568048248354}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/911.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/911.json
index 3381eb1f16b..bdb3d2fd517 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/911.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/911.json
@@ -1 +1 @@
-{"Blood bilirubin increased ": 11.154015452356177, "Blood lactate dehydrogenase increased ": 23.64673172684285, "Blood phosphorus increased ": 146.31354052446963, "Cardio-respiratory arrest ": 9.647796496922636, "Cardiovascular insufficiency ": 168.13610249659004, "Cerebral haematoma ": 73.30766422279504, "Cerebrovascular accident ": 3.08446484991966, "Chromaturia ": 25.7463132108657, "General physical health deterioration ": 8.370152932510361, "Haemolysis ": 138.26491241134434, "Haemolytic anaemia ": 154.15323944948963, "Haptoglobin decreased ": 437.31840994707375, "Hyperkalaemia ": 13.236460270616377, "Hypoxia ": 45.70352594967808, "Incorrect dose administered ": 8.514772546174397, "Methaemoglobinaemia ": 3269.9253194698936, "Nervous system disorder ": 19.946357158042847, "Oxygen saturation decreased ": 15.4096195532012, "Renal failure ": 2.247069171503802, "Respiratory failure ": 10.899152514129948, "Tumour lysis syndrome ": 142.40462717353353, "Ventricular fibrillation ": 29.93153726263183}
\ No newline at end of file
+{"Acute promyelocytic leukaemia": 1435.2248209618683, "Dehydration": 6.00140674342063, "Disease progression": 6.847177552873984, "Dysphagia": 6.5225254836408695, "Interstitial lung disease": 2.367174071577374, "Leukopenia": 5.927121037120441, "Mucosal inflammation": 20.097733810354235, "Neutropenia": 3.75917228880714, "Oedema": 3.7102596845300617, "Pancytopenia": 4.530630819096461, "Sepsis": 5.161862738354683, "Stevens-Johnson syndrome": 5.863591174985291, "Thrombocytopenia": 3.8635949444130886, "Weight decreased": 2.9366540026450085}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/912.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/912.json
index cd62f5b838c..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/912.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/912.json
@@ -1 +1 @@
-{"Acute kidney injury ": 3.020724710497884, "Angina pectoris ": 2.3125374202489866, "Angioedema ": 7.8232050529932655, "Anuria ": 3.9037176749672513, "Arrhythmia ": 2.036727684458403, "Atrioventricular block ": 3.3427948123194016, "Blood creatine increased ": 7.777418992279464, "Blood creatine phosphokinase increased ": 2.1304693899691984, "Blood creatinine increased ": 11.644014727329289, "Blood potassium decreased ": 2.0338621189914603, "Blood potassium increased ": 21.579952684977307, "Blood pressure abnormal ": 3.2204012504825035, "Blood pressure decreased ": 4.021953918358298, "Blood pressure diastolic decreased ": 18.59601325356756, "Blood pressure diastolic increased ": 13.765266594494973, "Blood pressure fluctuation ": 14.248234425507968, "Blood pressure inadequately controlled ": 110.24126918567978, "Blood pressure increased ": 12.384733768824791, "Blood pressure systolic decreased ": 6.780974278636445, "Blood pressure systolic increased ": 24.80130467433001, "Blood urea increased ": 18.10853668605657, "Blood uric acid increased ": 7.805911395008172, "Bradycardia ": 2.4043878779475967, "Brain natriuretic peptide increased ": 10.385910757321168, "Bundle branch block left ": 8.672868725766053, "Cerebrovascular accident ": 3.022984048799418, "Circulatory collapse ": 2.292286114997746, "Creatinine renal clearance decreased ": 12.017358610443214, "Dermatitis bullous ": 2.6820779592674424, "Diabetes mellitus ": 3.525906977290141, "Dysphagia ": 2.4838974968758816, "Extrasystoles ": 6.111300369107672, "Eyelid oedema ": 2.5551337913991423, "Face oedema ": 6.311605107907201, "Fluid retention ": 2.982521017744182, "Gamma-glutamyltransferase increased ": 3.882335517987928, "Generalised oedema ": 5.463655145441369, "Glomerular filtration rate decreased ": 14.738760835681012, "Glycosylated haemoglobin increased ": 4.017675890279441, "Gynaecomastia ": 3.058078914914629, "Heart rate decreased ": 2.701663508521147, "Hyperkalaemia ": 17.155751588825034, "Hypertension ": 3.4771411470739224, "Hypertensive crisis ": 10.961562570895266, "Hypokalaemia ": 2.2121733257128118, "Hyponatraemia ": 4.734463974048647, "Hypotension ": 2.1691298000529877, "Infarction ": 7.0628793897563735, "Ischaemia ": 7.462843935712358, "Lip oedema ": 2.67879431892859, "Nephropathy ": 4.016217036440081, "Oedema ": 4.357158260730562, "Oedema peripheral ": 4.973542272350369, "Oliguria ": 6.340160121615348, "Orthostatic hypotension ": 2.4046133224754143, "Periorbital oedema ": 7.242809684882715, "Pharyngeal oedema ": 4.069912583406109, "Proteinuria ": 9.098022280081588, "Pulmonary oedema ": 2.350026519253161, "Renal artery stenosis ": 26.609534044480124, "Renal disorder ": 2.932808354900674, "Renal failure ": 3.170024397725097, "Renal impairment ": 5.808477683964558, "Renin increased ": 277.7919181710361, "Swelling face ": 3.102168043210468, "Swollen tongue ": 3.0068297554335097, "Tachyarrhythmia ": 10.017809356779676, "Tongue oedema ": 3.5821056342397206, "Urine output decreased ": 5.28406996843585, "Wrong technique in product usage process ": 4.4064031125581655}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/913.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/913.json
index 7b18de3cf9d..16f7b2cafc1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/913.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/913.json
@@ -1 +1 @@
-{"Aggression ": 5.598032410133944, "Agitation ": 2.640265235905753, "Akathisia ": 204.8978556760539, "Anxiety ": 2.211963657728077, "Drug dose titration not performed ": 523.1307302031682, "Extrapyramidal disorder ": 27.447262021474742, "Insomnia ": 3.079737385748317, "Intentional product use issue ": 9.950928045305458, "Musculoskeletal stiffness ": 3.2188980435166887, "Off label use ": 4.99496807043089, "Parkinsonism ": 25.37826357570688, "Product use in unapproved indication ": 5.227669347252971, "Psychotic disorder ": 11.141630954124706, "Restlessness ": 22.962270011497527, "Salivary hypersecretion ": 21.94485867325364, "Sleep disorder ": 3.797216342306744, "Somnolence ": 2.105369344390159, "Tremor ": 4.376483914792225, "Vision blurred ": 5.436173658770063, "Weight increased ": 5.279379909331964}
\ No newline at end of file
+{"Acute myeloid leukaemia": 133.503888480076, "Disease progression": 6.680034192039005, "Myelodysplastic syndrome": 76.19645250821675}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/914.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/914.json
index 8f19238fa0f..7448aa964ec 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/914.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/914.json
@@ -1 +1 @@
-{"Abortion induced ": 7.991108066830665, "Adverse event ": 2.837206819599785, "Anaemia ": 18.232024984440663, "Ascites ": 6.4896854900750505, "Asthenia ": 2.379686899766692, "Blood bilirubin increased ": 4.853563273059305, "Blood uric acid increased ": 6.69092896809856, "Cardiac failure ": 2.3480582260699627, "Cholestasis ": 2.0124431549484507, "Cutaneous sarcoidosis ": 70.93362642569758, "Depression ": 3.4147703611952034, "Drug eruption ": 2.320608739067075, "Drug ineffective ": 3.424585574432775, "Dry skin ": 3.171585271804997, "Encephalopathy ": 2.1784189194327657, "Facial paralysis ": 2.117406766195512, "Glomerular filtration rate decreased ": 3.2845716783947854, "Haemoglobin decreased ": 8.788075623712455, "Haemolytic anaemia ": 32.980256969230524, "Hepatic cancer ": 4.745768428083379, "Hepatic cirrhosis ": 6.238490070092362, "Hepatic encephalopathy ": 15.975200747232927, "Hepatic failure ": 2.507551801256786, "Hepatitis C ": 65.45724903225579, "Hepatocellular carcinoma ": 13.099374481068653, "Hyperbilirubinaemia ": 8.776697948270735, "Hyperthyroidism ": 7.280634627887451, "Hyperuricaemia ": 12.16986048262845, "Hypoacusis ": 2.0878264192928864, "Hypothyroidism ": 4.474055923788559, "Injection site necrosis ": 24.38215089986352, "Irritability ": 2.274703117893857, "Jaundice ": 5.771683166589954, "Leukopenia ": 4.020799927642053, "Liver disorder ": 2.515200901213209, "Multiple organ dysfunction syndrome ": 2.1585928739019797, "Neutropenia ": 2.4041874359156963, "Oesophageal varices haemorrhage ": 25.72096970609256, "Optic neuritis ": 6.373349113214562, "Pancytopenia ": 2.3564283355813016, "Psychotic disorder ": 3.749073537722911, "Pulmonary arterial hypertension ": 4.08549793623459, "Pulmonary hypertension ": 2.5768268485475616, "Renal impairment ": 2.691304487493507, "Sarcoidosis ": 16.87702577164137, "Sinus bradycardia ": 4.087386703594066, "Suicide attempt ": 2.1258447297036347, "Thrombocytopenia ": 3.198893734368391, "Ventricular tachycardia ": 2.512822708227409, "Visual acuity reduced ": 3.059559508233645, "Weight decreased ": 2.357782935143437}
\ No newline at end of file
+{"Drug interaction": 9.530118811960705, "Immune reconstitution inflammatory syndrome": 165.08883489826445, "Psychiatric decompensation": 663.2396778811935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/915.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/915.json
index c29da5885d3..c6e17281db0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/915.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/915.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 2.547049040670156, "Amenorrhoea ": 3.167374425977623, "Aspartate aminotransferase increased ": 2.602214792704238, "Balance disorder ": 2.878996748622836, "Fall ": 2.6553886751272886, "Gait disturbance ": 3.56838493303375, "Generalised tonic-clonic seizure ": 5.634915864517315, "Hepatic enzyme increased ": 7.643155245745204, "Hypoaesthesia ": 2.05482522144224, "Injection site bruising ": 15.851783606178689, "Injection site erythema ": 3.518185216469681, "Leukopenia ": 2.181621907874316, "Liver injury ": 8.366328612052788, "Localised oedema ": 19.055221364108395, "Loss of consciousness ": 3.719894503194017, "Multiple sclerosis ": 25.67628620896644, "Multiple sclerosis relapse ": 23.640733938495227, "Seizure ": 2.644151316550925, "Suicidal ideation ": 2.160959104690464, "Trigeminal neuralgia ": 30.73996218134699, "Urinary tract infection ": 2.851988852210567}
\ No newline at end of file
+{"Amnesia": 3.06078726370813, "Angina pectoris": 8.825517861269901, "Balance disorder": 2.683423784712419, "Blood creatinine increased": 2.1424472983394653, "Blood pressure decreased": 2.990714161009821, "Bradycardia": 3.3453749463759723, "Cardiac failure": 2.2227169593197216, "Chromaturia": 14.44729951282272, "Confusional state": 2.508211412146361, "Constipation": 8.068916833641287, "Disorientation": 2.815224351009764, "Dizziness": 4.16339268289376, "Drug interaction": 3.80848408579945, "Dry mouth": 5.052210979262974, "Dyspepsia": 2.473764833965856, "Dysuria": 2.742075923854959, "Electrocardiogram QT prolonged": 5.54930487941373, "Flatulence": 3.698013240422013, "Glomerular filtration rate decreased": 6.02218835659011, "Hallucination": 3.229017383635012, "Hallucination, visual": 6.560073753302664, "Hyperhidrosis": 2.028537912237953, "Hyponatraemia": 4.21310433504435, "Hypotension": 2.763317879488206, "Labelled drug-drug interaction medication error": 4.589921357920211, "Off label use": 2.3338844891240837, "Orthostatic hypotension": 6.360893294511393, "Rhabdomyolysis": 3.551616840388013, "Syncope": 2.789427142435323, "Tinnitus": 3.5800039582897085, "Torsade de pointes": 12.64698954549783, "Underdose": 7.858868622907402, "Ventricular tachycardia": 6.273515621681442, "Vertigo": 3.287332223961009, "Vision blurred": 4.3750695015231225, "Visual impairment": 2.260566440901425, "Wrong technique in product usage process": 3.366464162472266}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/916.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/916.json
index 5e2279eafbb..d28ae6d588f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/916.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/916.json
@@ -1 +1 @@
-{"Asthenia ": 3.7133359690424186, "Bone pain ": 23.16044402044602, "Dizziness ": 2.026849927475605, "Extramedullary haemopoiesis ": 2219.0164051742645, "Fall ": 2.168293652437793, "Haemoglobin decreased ": 18.306211593979267, "Hypertension ": 2.1647440688028614, "Syncope ": 2.328231048312288}
\ No newline at end of file
+{"Cough": 16.44456195880211, "Dyspnoea": 7.711361253042746, "Lower respiratory tract infection": 119.9638786744081}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/917.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/917.json
index 41f49541b9d..4c332378f13 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/917.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/917.json
@@ -1 +1 @@
-{"Foetal distress syndrome ": 977.5496199059312, "Ovarian hyperstimulation syndrome ": 1077.885177931513, "Umbilical cord abnormality ": 5651.195571258748}
\ No newline at end of file
+{"Angina pectoris": 18.4296308397781, "Blood creatinine increased": 2.227887020088801, "Cardiac arrest": 3.9003529525993774, "Cardiac disorder": 3.482669517586212, "Cardiac failure congestive": 3.644308427331665, "Cardiac operation": 38.77372094667076, "Cardiac pacemaker insertion": 30.689058500274395, "Cerebrovascular accident": 3.8259787118513366, "Chest pain": 3.7942097068828007, "Chromaturia": 7.140668111941144, "Completed suicide": 2.134025833840385, "Constipation": 3.7121878971298976, "Coronary arterial stent insertion": 55.06700379693664, "Coronary artery disease": 3.265290094761527, "Death": 6.898066994844456, "Dementia": 7.619257816376308, "Diabetes mellitus": 4.661594047273731, "Dizziness": 2.4691553428123387, "Drug interaction": 5.185624994608356, "Electrocardiogram QT prolonged": 14.392136698131354, "Fall": 2.430809314144166, "Hallucination": 5.94244126177556, "Hallucination, visual": 5.168106004558706, "Heart rate decreased": 5.70689113614341, "Hypoacusis": 6.34936203738101, "Hypotension": 2.257328801122673, "Loss of consciousness": 3.002276001767014, "Medication error": 2.5666946456225723, "Myocardial infarction": 6.369605078928369, "Orthostatic hypotension": 6.474868068459282, "Parkinson's disease": 8.306014249681576, "Product residue present": 16.90370673062155, "Renal impairment": 2.603503655568425, "Rhabdomyolysis": 4.685660491757384, "Stent placement": 95.27640926373576, "Syncope": 2.5327769119087056, "Torsade de pointes": 19.51608325145857, "Unevaluable event": 12.18475737516159, "Urinary retention": 4.446116108841981, "Ventricular fibrillation": 8.780738603230352, "Ventricular tachycardia": 12.108423842729298, "Wrong technique in product usage process": 3.714944082924613}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/918.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/918.json
index 815ddcc5675..80a1c56b361 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/918.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/918.json
@@ -1 +1 @@
-{"Thrombocytopenia ": 17.91421414280298}
\ No newline at end of file
+{"Acne": 2.4818370161400414, "Aphthous ulcer": 5.986774848624158, "Blindness": 2.990426319810477, "Blood cholesterol increased": 2.7404945975311823, "Blood creatinine increased": 4.452429368913793, "Blood triglycerides increased": 4.7580380974588525, "Body height decreased": 6.115499481562083, "Cardiac disorder": 2.204672541202929, "Cellulitis": 2.4725576547401005, "Cerebrovascular accident": 2.4490597245034764, "Clostridium difficile infection": 2.51916040141848, "Cytomegalovirus infection": 6.980496809845114, "Deep vein thrombosis": 2.811605695810575, "Dementia": 2.853508995015115, "Diabetes mellitus": 4.211250647469139, "Drug effective for unapproved indication": 12.74091358563846, "Drug ineffective for unapproved indication": 7.069685083205627, "Drug interaction": 2.0259744734730334, "Drug level below therapeutic": 15.15228615509752, "Drug level decreased": 15.09851901212829, "Drug level increased": 13.010780518325117, "End stage renal disease": 2.715726517094673, "Expired product administered": 5.438286052108444, "Fluid retention": 2.5162120134326478, "Graft versus host disease": 14.82187447314644, "Haemolytic uraemic syndrome": 82.4760154314649, "Heart transplant": 108.9795613801014, "Heart transplant rejection": 73.22073397811435, "Hernia": 15.523409771896915, "Hip fracture": 4.302485156603666, "Hyperlipidaemia": 4.32226579628449, "Hypertriglyceridaemia": 8.736339237483916, "Illness": 3.259638513734751, "Immune system disorder": 4.535879017358669, "Immunosuppressant drug level increased": 77.75198356218219, "Impaired healing": 7.295174682214194, "Infection": 3.435654585357883, "Interstitial lung disease": 6.662818504169086, "Kidney transplant rejection": 70.48627913963772, "Liver transplant": 18.495881322647573, "Liver transplant rejection": 63.5703406826392, "Localised infection": 3.5353796968655518, "Lower limb fracture": 3.085301404062286, "Lung disorder": 4.832913912794032, "Lung infiltration": 11.90821688888021, "Lung neoplasm malignant": 3.044617178879164, "Lymphoedema": 15.362788811535568, "Lymphoma": 7.331350318131109, "Mouth ulceration": 7.696760851376101, "Neoplasm malignant": 4.099530097592688, "Nephrotic syndrome": 6.082112611179107, "Oedema": 2.9567723431657407, "Oedema peripheral": 2.281822116079012, "Off label use": 5.934213723749807, "Organising pneumonia": 16.672601347505243, "Pericardial effusion": 5.731998990939738, "Pleural effusion": 2.0309991571218595, "Pneumocystis jirovecii pneumonia": 7.110986410048895, "Pneumonia": 4.142606577946034, "Pneumonitis": 20.92926916770092, "Post transplant lymphoproliferative disorder": 9.415797922665076, "Product dispensing error": 3.1038582586778425, "Product prescribing error": 10.12193381331981, "Product use in unapproved indication": 15.236936411001528, "Product use issue": 3.612349115396361, "Proteinuria": 11.55672689708816, "Pulmonary fibrosis": 5.705139472265844, "Pulmonary haemorrhage": 6.99616499210777, "Renal disorder": 6.504318770499427, "Renal failure": 2.7808659101821727, "Renal impairment": 3.097916045124932, "Renal tubular necrosis": 6.25641670946037, "Respiratory failure": 2.5002341475725047, "Sepsis": 3.5210145362748517, "Skin cancer": 26.022778122438574, "Skin ulcer": 2.952298791220254, "Stomatitis": 2.368790885482216, "Thrombotic microangiopathy": 17.69832113023242, "Transplant rejection": 63.44327154322768, "Urinary tract infection": 3.219733003068713, "Viral infection": 2.899650736491915}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/919.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/919.json
index f2cff89b414..d9114849112 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/919.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/919.json
@@ -1 +1 @@
-{"Blood pressure decreased ": 16.443055458439936, "Bradycardia ": 15.877785184013655, "Cardiac arrest ": 24.92043848809712, "Dizziness ": 2.141413942198809, "Dyspnoea ": 2.085164273528345, "Heart rate decreased ": 69.67538769661037, "Hypotension ": 5.856244313440031, "Loss of consciousness ": 12.84259758677844, "Nausea ": 2.3304190977873755}
\ No newline at end of file
+{"Cardiac arrest": 12.686668756011954, "Cerebral haemorrhage": 325.604758280221}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/92.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/92.json
index b6fc0f25ea0..031616135a5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/92.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/92.json
@@ -1 +1 @@
-{"Completed suicide ": 264.4547767318826}
\ No newline at end of file
+{"Cardio-respiratory arrest": 28.451591621534977, "Completed suicide": 24.422629074771876, "Overdose": 9.430591807736656}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/920.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/920.json
index 7e076ad3a6b..4f1e5c51f61 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/920.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/920.json
@@ -1 +1 @@
-{"Asthenia ": 2.9435838743004075, "Colorectal cancer metastatic ": 397.3651147397352, "Decreased appetite ": 2.0713801593944225, "Diarrhoea ": 2.809967493333536, "Drug intolerance ": 3.873010062679604, "Dysphonia ": 5.548416506217792, "Encephalopathy ": 9.23306606636068, "Gastrointestinal stromal tumour ": 37.71499409464941, "General physical health deterioration ": 3.087177415854483, "Hepatocellular carcinoma ": 24.1944534690259, "Hypertension ": 3.246599268796801, "Hypothyroidism ": 5.385802107028406, "Metastases to lung ": 39.116001822785215, "Mucosal inflammation ": 16.534102229623297, "Oedema peripheral ": 2.3460148261258373, "Off label use ": 3.943005251426815, "Palmar-plantar erythrodysaesthesia syndrome ": 87.94473375117687, "Platelet count decreased ": 2.2626307378641197, "Product use in unapproved indication ": 2.5693435902860995, "Stomatitis ": 9.67790234399723, "Thrombocytopenia ": 2.37662727164976, "Venous thrombosis ": 30.666122971379}
\ No newline at end of file
+{"Angina pectoris": 9.12085758322994, "Atrioventricular block": 57.79364215928979, "Atrioventricular block complete": 50.46396821372571, "Blood pressure decreased": 14.937819167972016, "Bradycardia": 14.423994458768666, "Bronchospasm": 24.44311556697105, "Cardiac arrest": 27.998892804404505, "Chest discomfort": 8.074577412658899, "Chest pain": 2.6491982543369024, "Discomfort": 19.64906753404985, "Dizziness": 3.008924719437027, "Dyspnoea": 4.02778272272898, "Heart rate decreased": 22.20754325626869, "Heart rate increased": 4.62292254968632, "Hypotension": 8.684506028729349, "Incorrect product administration duration": 28.680268685146057, "Loss of consciousness": 2.557020076098976, "Nausea": 2.129860263645919, "Presyncope": 4.7424936056094, "Sinus bradycardia": 29.78775491236836, "Vomiting": 2.426960521299274}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/921.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/921.json
index 0d658f4c762..353af25eba5 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/921.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/921.json
@@ -1 +1 @@
-{"Back pain ": 3.942802078297676, "Blood HIV RNA increased ": 271.67295980081406, "Depression ": 2.248412034285012, "Discomfort ": 4.082689725855926, "Drug level decreased ": 57.38686858310708, "Gait disturbance ": 3.320230228748158, "Injection site pain ": 13.865626365221038, "Injection site reaction ": 6.399790897747688, "Injection site swelling ": 3.4304522456163618, "Pain ": 2.384535265350324, "Pathogen resistance ": 96.76241974462664, "Viral load increased ": 155.6588293864485, "Virologic failure ": 251.4775160400662, "Weight increased ": 2.483159975083899}
\ No newline at end of file
+{"Completed suicide": 11.766182062559732, "Drug interaction": 5.698655364636911, "Erectile dysfunction": 41.3728581767196, "Impulse-control disorder": 882.9245621992858, "Product use in unapproved indication": 8.102946685416827, "Suicidal ideation": 14.328539877611613, "Therapeutic product ineffective": 305.2553639664196}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/922.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/922.json
index b94f4c64115..35ec44e3976 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/922.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/922.json
@@ -1 +1 @@
-{"Ovarian hyperstimulation syndrome ": 3327.7200146559853}
\ No newline at end of file
+{"Blood bilirubin increased": 11.154015452356177, "Blood lactate dehydrogenase increased": 23.64673172684285, "Blood phosphorus increased": 146.31354052446963, "Cardio-respiratory arrest": 9.647796496922636, "Cardiovascular insufficiency": 168.13610249659004, "Cerebral haematoma": 73.30766422279504, "Cerebrovascular accident": 3.084409273093698, "Chromaturia": 25.7463132108657, "General physical health deterioration": 8.370152932510361, "Haemolysis": 138.26491241134434, "Haemolytic anaemia": 154.15323944948963, "Haptoglobin decreased": 437.31840994707375, "Hyperkalaemia": 13.234635209063669, "Hypoxia": 45.70352594967808, "Incorrect dose administered": 8.514772546174397, "Methaemoglobinaemia": 3269.9253194698936, "Nervous system disorder": 19.946357158042847, "Oxygen saturation decreased": 15.40879497277496, "Renal failure": 2.247069171503802, "Respiratory failure": 10.89825260181389, "Tumour lysis syndrome": 142.40462717353353, "Ventricular fibrillation": 29.93153726263183}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/923.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/923.json
index c1f46b42366..280e981968b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/923.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/923.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 5.576907565481223, "Ageusia ": 2.823288073136704, "Anosmia ": 2.0925802073220106, "Aphonia ": 30.51226266383044, "Arrhythmia ": 4.282954944881019, "Asphyxia ": 6.067461207006208, "Asthma ": 6.960243949973473, "Asthmatic crisis ": 30.26217356100068, "Atrial fibrillation ": 2.089379859304194, "Bronchitis ": 4.115848754047945, "Bronchospasm ": 3.936047924660193, "Candida infection ": 5.334674592976599, "Catarrh ": 26.42466552980598, "Chest discomfort ": 2.308950098146111, "Choking ": 2.25901327344108, "Chondrocalcinosis pyrophosphate ": 93.25621789278247, "Chronic obstructive pulmonary disease ": 6.213368967533156, "Circumstance or information capable of leading to medication error ": 15.410906890518753, "Condition aggravated ": 2.513717048238201, "Cortisol decreased ": 15.227233177621487, "Cough ": 6.898081279643288, "Diabetes insipidus ": 16.073984553197953, "Drug effective for unapproved indication ": 8.500690464997428, "Dry throat ": 9.742195190180274, "Dysphonia ": 33.792573790431014, "Dyspnoea ": 2.9640114966299103, "Eating disorder ": 3.762094569898144, "Emphysema ": 3.851770109581901, "Expired product administered ": 3.9985712147781696, "Extra dose administered ": 4.5492002493578765, "Fear ": 2.532557645150189, "Foreign body in throat ": 22.69287823451069, "Fungal pharyngitis ": 340.40051701151395, "Gingival pain ": 5.894959156646763, "Glaucoma ": 7.038878443668379, "Hospitalisation ": 2.9856774168532887, "Ill-defined disorder ": 2.139037416133213, "Intraocular pressure increased ": 3.99466733483196, "Laryngeal oedema ": 3.224186413642008, "Lower respiratory tract infection ": 2.4164460110353843, "Lung neoplasm malignant ": 2.6712682466585123, "Meningitis bacterial ": 78.16649334527607, "Muscle spasms ": 3.577001240784488, "Nasal congestion ": 2.1806746573014086, "Nasal discomfort ": 7.073219053252065, "Nasopharyngitis ": 3.448637728775523, "Oesophageal candidiasis ": 66.59835607258583, "Oral candidiasis ": 16.899030218835332, "Oral discomfort ": 3.715956572333219, "Oral fungal infection ": 38.87649016416324, "Oral pain ": 9.455345454321089, "Oropharyngeal discomfort ": 10.203478245219232, "Oropharyngeal pain ": 5.264133473007273, "Palpitations ": 4.144310787372008, "Pharyngeal disorder ": 17.448855258315934, "Pneumonia ": 4.881886342878162, "Prinzmetal angina ": 44.71070060516731, "Product complaint ": 30.238638022036778, "Product dispensing error ": 5.725191939227428, "Product prescribing issue ": 15.583271941775324, "Product use in unapproved indication ": 4.397950488189578, "Product use issue ": 2.666644847523653, "Productive cough ": 11.25046981692471, "Respiratory disorder ": 3.514729056504451, "Respiratory tract infection ": 4.929279872948509, "Rhinitis ": 5.311119912738873, "Rhinorrhoea ": 4.4430348512079245, "Secretion discharge ": 14.602789823252406, "Sinusitis ": 3.3306636833816903, "Sneezing ": 2.589535172552131, "Sputum discoloured ": 11.523325737033844, "Sputum increased ": 14.938655172918264, "Swelling face ": 2.7047711913816075, "Tachycardia ": 2.456254395304755, "Taste disorder ": 2.425311472002749, "Therapy cessation ": 15.072118274292484, "Therapy interrupted ": 9.036383435462415, "Thirst ": 2.8741825692157703, "Throat irritation ": 10.43816140683952, "Treatment noncompliance ": 5.24180192742852, "Urinary retention ": 2.5977026904614884, "Vision blurred ": 2.0795925226371463, "Wheezing ": 5.819673347343997, "Wrong technique in device usage process ": 14.343819251116912, "Wrong technique in product usage process ": 3.6732576530044745}
\ No newline at end of file
+{"Acute kidney injury": 3.020724710497884, "Angina pectoris": 2.3125374202489866, "Angioedema": 7.8232050529932655, "Anuria": 3.9037176749672513, "Arrhythmia": 2.036727684458403, "Atrioventricular block": 3.3427948123194016, "Blood creatine increased": 7.777418992279464, "Blood creatine phosphokinase increased": 2.1304693899691984, "Blood creatinine increased": 11.644014727329289, "Blood potassium decreased": 2.0338621189914603, "Blood potassium increased": 21.579952684977307, "Blood pressure abnormal": 3.2204012504825035, "Blood pressure decreased": 4.0218231947768, "Blood pressure diastolic decreased": 18.59601325356756, "Blood pressure diastolic increased": 13.765266594494973, "Blood pressure fluctuation": 14.248234425507968, "Blood pressure inadequately controlled": 110.24126918567978, "Blood pressure increased": 12.38451530727266, "Blood pressure systolic decreased": 6.780974278636445, "Blood pressure systolic increased": 24.80130467433001, "Blood urea increased": 18.10853668605657, "Blood uric acid increased": 7.805911395008172, "Bradycardia": 2.404312468317784, "Brain natriuretic peptide increased": 10.385910757321168, "Bundle branch block left": 8.672868725766053, "Cerebrovascular accident": 3.022929512830109, "Circulatory collapse": 2.292286114997746, "Creatinine renal clearance decreased": 12.017358610443214, "Dermatitis bullous": 2.6820779592674424, "Diabetes mellitus": 3.525906977290141, "Dysphagia": 2.4838974968758816, "Extrasystoles": 6.111300369107672, "Eyelid oedema": 2.5551337913991423, "Face oedema": 6.311605107907201, "Fluid retention": 2.982521017744182, "Gamma-glutamyltransferase increased": 3.882335517987928, "Generalised oedema": 5.463655145441369, "Glomerular filtration rate decreased": 14.738760835681012, "Glycosylated haemoglobin increased": 4.017675890279441, "Gynaecomastia": 3.058078914914629, "Heart rate decreased": 2.701663508521147, "Hyperkalaemia": 17.15336972693913, "Hypertension": 3.4771052029663565, "Hypertensive crisis": 10.961562570895266, "Hypokalaemia": 2.2121733257128118, "Hyponatraemia": 4.734463974048647, "Hypotension": 2.169079614556972, "Infarction": 7.0628793897563735, "Ischaemia": 7.462843935712358, "Lip oedema": 2.67879431892859, "Nephropathy": 4.016217036440081, "Oedema": 4.357158260730562, "Oedema peripheral": 4.973419124597151, "Oliguria": 6.340160121615348, "Orthostatic hypotension": 2.4040955218865854, "Periorbital oedema": 7.242809684882715, "Pharyngeal oedema": 4.069912583406109, "Proteinuria": 9.098022280081588, "Pulmonary oedema": 2.349717784580712, "Renal artery stenosis": 26.609534044480124, "Renal disorder": 2.9323753659329768, "Renal failure": 3.170024397725097, "Renal impairment": 5.808477683964558, "Renin increased": 277.7919181710361, "Swelling face": 3.102168043210468, "Swollen tongue": 3.0068297554335097, "Tachyarrhythmia": 10.017809356779676, "Tongue oedema": 3.5821056342397206, "Urine output decreased": 5.28406996843585, "Wrong technique in product usage process": 4.4064031125581655}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/924.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/924.json
index 0aef34a02af..a2eca17fcca 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/924.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/924.json
@@ -1 +1 @@
-{"Acute kidney injury ": 9.6122885636872, "Acute myocardial infarction ": 3.137319701777584, "Acute respiratory distress syndrome ": 27.42513871336273, "Acute respiratory failure ": 26.153673107560103, "Alanine aminotransferase increased ": 25.074898089188316, "Aspartate aminotransferase increased ": 14.829419653001407, "Atrial fibrillation ": 2.2062097818313853, "Blood alkaline phosphatase increased ": 3.67356092029822, "Blood bilirubin increased ": 4.199809219536897, "Blood creatinine increased ": 9.449955324404542, "Blood triglycerides increased ": 9.456787126350733, "Blood urea increased ": 4.529319273436117, "Bradycardia ": 15.6021801938931, "COVID-19 ": 2.779836896160895, "COVID-19 pneumonia ": 34.16984159973498, "Cardiac arrest ": 9.544766330907946, "Cardio-respiratory arrest ": 3.031695682983375, "Death ": 8.945811105956519, "Disseminated intravascular coagulation ": 8.639118048273067, "Drug-induced liver injury ": 3.278399778694161, "Electrocardiogram QT prolonged ": 2.6444020657148237, "Endotracheal intubation ": 20.5522805833344, "Extravasation ": 32.38295497765729, "General physical health deterioration ": 2.3493561834712917, "Glomerular filtration rate decreased ": 14.186033443450928, "Hepatic enzyme increased ": 9.633870317623938, "Hepatotoxicity ": 3.849337103795701, "Hyperkalaemia ": 2.961959490168129, "Hypertransaminasaemia ": 37.69700841893579, "Hypotension ": 2.9828605546599083, "Hypoxia ": 11.119021530987798, "Infusion related reaction ": 2.2953720974986123, "Infusion site extravasation ": 58.33157472813883, "Intentional product use issue ": 2.639631552368108, "International normalised ratio increased ": 5.873059800814072, "Liver disorder ": 2.712353451945241, "Liver function test abnormal ": 5.731896059626332, "Liver function test increased ": 41.2207836061092, "Maternal exposure during pregnancy ": 2.570930384658349, "Multiple organ dysfunction syndrome ": 6.540283728499924, "Off label use ": 2.6884197644644914, "Oxygen saturation decreased ": 5.526829435949915, "Pneumonia bacterial ": 18.027379736028927, "Pneumothorax ": 7.581352114885695, "Prothrombin time prolonged ": 22.83539663124758, "Pulseless electrical activity ": 51.05635158737004, "Renal failure ": 2.3525759179727714, "Renal impairment ": 4.568971597331571, "Respiratory disorder ": 5.026750708682881, "Respiratory distress ": 5.0394890505583625, "Respiratory failure ": 10.4104874194691, "Sepsis ": 2.3707818521360173, "Septic shock ": 15.951058928548616, "Shock ": 9.061589255036733, "Sinus bradycardia ": 26.579423334869126, "Transaminases increased ": 19.25505229513693}
\ No newline at end of file
+{"Aggression": 5.598032410133944, "Agitation": 2.640265235905753, "Akathisia": 204.8978556760539, "Anxiety": 2.211963657728077, "Drug dose titration not performed": 523.1307302031682, "Extrapyramidal disorder": 27.447262021474742, "Insomnia": 3.079737385748317, "Intentional product use issue": 9.950928045305458, "Musculoskeletal stiffness": 3.2188980435166887, "Off label use": 4.9947712871891286, "Parkinsonism": 25.37826357570688, "Product use in unapproved indication": 5.227506292378009, "Psychotic disorder": 11.141630954124706, "Restlessness": 22.96105733939289, "Salivary hypersecretion": 21.934175384363066, "Sleep disorder": 3.797216342306744, "Somnolence": 2.105346136648905, "Tremor": 4.376318576622997, "Vision blurred": 5.436173658770063, "Weight increased": 5.279379909331964}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/925.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/925.json
index d6336e14f9b..a8796fb7071 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/925.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/925.json
@@ -1 +1 @@
-{"Abdominal abscess ": 19.104396055116244, "Abortion spontaneous ": 2.665193559768155, "Abscess ": 7.668284365493086, "Acute myeloid leukaemia ": 2.7029026858615635, "Adverse drug reaction ": 2.427842356575271, "Adverse event ": 2.8093108397832336, "Anal abscess ": 17.675508223543115, "Basal cell carcinoma ": 3.964363311934308, "Bronchitis ": 2.639988332263864, "Candida infection ": 2.821203497001449, "Cellulitis ": 5.585064463023184, "Cholelithiasis ": 2.5652755038623924, "Clostridium difficile infection ": 3.87603304316962, "Colitis ulcerative ": 15.757576647736396, "Colon cancer ": 5.792730116682801, "Crohn's disease ": 19.046555825202717, "Cystitis ": 2.143705703833588, "Cytomegalovirus enterocolitis ": 51.1697142267506, "Cytomegalovirus infection ": 4.11502091357783, "Disseminated tuberculosis ": 41.16119385855462, "Diverticulitis ": 2.292621472783309, "Drug hypersensitivity ": 3.113587102591687, "Drug level decreased ": 7.737995471831603, "Enterobacter infection ": 37.7251054598289, "Exposure during pregnancy ": 6.3994500945255375, "Failed induction of labour ": 228.65543822595637, "Fistula ": 13.194692378923865, "Flushing ": 3.5933305221984795, "Foetal exposure during pregnancy ": 2.8597898514257443, "Frequent bowel movements ": 8.336665048231776, "Fungal infection ": 3.647488837559584, "Gastroenteritis viral ": 6.554932603680343, "Haematochezia ": 3.4020450664099515, "Hidradenitis ": 20.12228760304287, "IgA nephropathy ": 23.9725461664861, "Ileus ": 3.524663454743522, "Infusion related reaction ": 23.21810735084618, "Interstitial lung disease ": 5.1745275017153975, "Intestinal obstruction ": 3.2002196832843595, "Limb injury ": 3.122272862381916, "Lupus-like syndrome ": 29.57930730518999, "Lymphoma ": 6.843388527387275, "Malignant melanoma ": 4.3288275580812, "Mass ": 3.624027825682425, "Multiple sclerosis ": 2.0808923698063366, "Neutropenia neonatal ": 157.16266732289336, "Off label use ": 2.295733292139732, "Omphalitis ": 251.48931049945924, "Peritonitis ": 4.537027281568919, "Pneumocystis jirovecii pneumonia ": 12.640648091353777, "Pneumonia ": 2.7354913875660363, "Premature baby ": 7.443935901091317, "Premature delivery ": 5.9763552053955245, "Product use issue ": 3.485480502919315, "Pseudomonas infection ": 7.224403936982364, "Psoriasis ": 4.827795061340399, "Pulmonary tuberculosis ": 12.658438972541102, "Pyelonephritis ": 4.416570981206986, "Rheumatoid arthritis ": 2.638624540669191, "Secretion discharge ": 6.240882597623904, "Sinusitis ": 2.495202229720168, "Skin laceration ": 4.9932190871523705, "Squamous cell carcinoma ": 7.212812928915743, "Staphylococcal infection ": 6.733513779723356, "Stillbirth ": 9.583123129392495, "Subarachnoid haemorrhage ": 3.1318327198049123, "Therapeutic product effect decreased ": 3.021511327266667, "Therapeutic product effect incomplete ": 2.195063013434256, "Therapeutic response decreased ": 4.674408038362124, "Threatened labour ": 69.01151818158482, "Tuberculosis ": 8.73934780247895, "Urinary tract infection ": 2.2666779473146543, "Vasculitis ": 2.7525228280663736, "White blood cell count increased ": 2.5164782502941474}
\ No newline at end of file
+{"Abortion induced": 7.991108066830665, "Adverse event": 2.837206819599785, "Anaemia": 18.232024984440663, "Ascites": 6.4896854900750505, "Asthenia": 2.379592181090076, "Blood bilirubin increased": 4.853563273059305, "Blood uric acid increased": 6.69092896809856, "Cardiac failure": 2.3478437891780706, "Cholestasis": 2.0124431549484507, "Cutaneous sarcoidosis": 70.93362642569758, "Depression": 3.4147703611952034, "Drug eruption": 2.320608739067075, "Drug ineffective": 3.424560233948199, "Dry skin": 3.171585271804997, "Encephalopathy": 2.1784189194327657, "Facial paralysis": 2.117406766195512, "Glomerular filtration rate decreased": 3.2845716783947854, "Haemoglobin decreased": 8.788075623712455, "Haemolytic anaemia": 32.980256969230524, "Hepatic cancer": 4.745768428083379, "Hepatic cirrhosis": 6.238490070092362, "Hepatic encephalopathy": 15.975200747232927, "Hepatic failure": 2.507551801256786, "Hepatitis C": 65.45724903225579, "Hepatocellular carcinoma": 13.099374481068653, "Hyperbilirubinaemia": 8.776697948270735, "Hyperthyroidism": 7.27997098558161, "Hyperuricaemia": 12.16986048262845, "Hypoacusis": 2.087650728614624, "Hypothyroidism": 4.474055923788559, "Injection site necrosis": 24.38215089986352, "Irritability": 2.2745944551256123, "Jaundice": 5.771683166589954, "Leukopenia": 4.020292571468466, "Liver disorder": 2.515200901213209, "Multiple organ dysfunction syndrome": 2.1585928739019797, "Neutropenia": 2.404083989859592, "Oesophageal varices haemorrhage": 25.72096970609256, "Optic neuritis": 6.373349113214562, "Pancytopenia": 2.3564283355813016, "Psychotic disorder": 3.749073537722911, "Pulmonary arterial hypertension": 4.08549793623459, "Pulmonary hypertension": 2.5768268485475616, "Renal impairment": 2.691304487493507, "Sarcoidosis": 16.87702577164137, "Sinus bradycardia": 4.087386703594066, "Suicide attempt": 2.1258447297036347, "Thrombocytopenia": 3.19859255387423, "Ventricular tachycardia": 2.512822708227409, "Visual acuity reduced": 3.059559508233645, "Weight decreased": 2.357782935143437}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/926.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/926.json
index 8597f014d6f..7c82b07366e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/926.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/926.json
@@ -1 +1 @@
-{"Abdominal pain ": 6.064764127533578, "Abdominal pain upper ": 2.6714991153295933, "Condition aggravated ": 3.03605788152068, "Defaecation urgency ": 138.6835707644756, "Diarrhoea ": 4.914727876732181, "Flatulence ": 18.670338473500045, "Frequent bowel movements ": 24.48324583090658, "Haematochezia ": 22.43208258586061, "Infection ": 3.401989397300177, "Intentional dose omission ": 161.68423900628736, "Intentional product use issue ": 9.529521865024185, "Lower respiratory tract infection ": 38.60930812577993, "Mucous stools ": 230.5545196447674, "Oropharyngeal pain ": 3.1328507814803235, "Product dose omission issue ": 4.1373207573419375, "Stress ": 19.057788030558893, "Weight decreased ": 8.422461160119319, "Weight increased ": 13.87420717167038}
\ No newline at end of file
+{"Alanine aminotransferase increased": 2.547049040670156, "Amenorrhoea": 3.167374425977623, "Aspartate aminotransferase increased": 2.602214792704238, "Balance disorder": 2.878996748622836, "Fall": 2.655320602926112, "Gait disturbance": 3.568320237662436, "Generalised tonic-clonic seizure": 5.634915864517315, "Hepatic enzyme increased": 7.643155245745204, "Hypoaesthesia": 2.05482522144224, "Injection site bruising": 15.851783606178689, "Injection site erythema": 3.518185216469681, "Leukopenia": 2.181346946211807, "Liver injury": 8.366328612052788, "Localised oedema": 19.055221364108395, "Loss of consciousness": 3.719712435159477, "Multiple sclerosis": 25.67628620896644, "Multiple sclerosis relapse": 23.640733938495227, "Seizure": 2.6438581835515613, "Suicidal ideation": 2.160959104690464, "Trigeminal neuralgia": 30.73996218134699, "Urinary tract infection": 2.851988852210567}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/927.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/927.json
index aa870bb9241..b0e82cb3ebe 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/927.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/927.json
@@ -1 +1 @@
-{"Dermatitis contact ": 352.636519738192, "Drug ineffective ": 2.4656375791012284, "Eosinophilia ": 31.80448542443745, "Medical device site reaction ": 51920.25683250734, "Muscle rigidity ": 157.05964573374231, "Muscle spasticity ": 228.41890069735095, "Musculoskeletal stiffness ": 25.34841798684741, "Pallor ": 55.62891914932019, "Rash erythematous ": 15.011186979440405, "Renal failure ": 4.79618968911098, "Scab ": 284.79312495783785, "Skin atrophy ": 569.6801783734003, "Skin exfoliation ": 60.35200244047112, "Skin haemorrhage ": 300.8721480257964, "Skin plaque ": 346.5218211341869}
\ No newline at end of file
+{"Asthenia": 3.713188259149104, "Bone pain": 23.16044402044602, "Dizziness": 2.0268358566460973, "Extramedullary haemopoiesis": 2219.0164051742645, "Fall": 2.168238075307737, "Haemoglobin decreased": 18.306211593979267, "Hypertension": 2.1647217229558424, "Syncope": 2.328199008701451}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/928.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/928.json
index ad44713559c..758f670592d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/928.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/928.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.3388852017317108, "Altered state of consciousness ": 5.84545652419119, "Blood glucose decreased ": 5.147961219419824, "Blood glucose increased ": 2.940196085464504, "Depressed level of consciousness ": 3.56984247287949, "Drug interaction ": 8.326404360676671, "Glycosylated haemoglobin increased ": 10.050717719234516, "Hyperglycaemia ": 4.522722420950192, "Hyperkalaemia ": 5.779241485716969, "Hypoglycaemia ": 71.80485213169372, "Hypoglycaemic coma ": 74.39386919495901, "Inappropriate schedule of product administration ": 3.0792771849677902, "Lactic acidosis ": 20.635407602360583, "Loss of consciousness ": 2.572741501472916, "Medication error ": 17.689220306166497, "Metabolic acidosis ": 11.586812331360129, "Myoclonus ": 12.87899500681118, "Pancreatitis acute ": 5.093129475791856, "Sopor ": 44.78243475853676}
\ No newline at end of file
+{"Foetal distress syndrome": 977.5496199059312, "Ovarian hyperstimulation syndrome": 1077.885177931513, "Umbilical cord abnormality": 5651.195571258748}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/929.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/929.json
index 0db37951d11..0f2acd3341a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/929.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/929.json
@@ -1 +1 @@
-{"Back pain ": 2.934197525506811, "Myalgia ": 2.185215636451157}
\ No newline at end of file
+{"Thrombocytopenia": 17.912529127950688}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/93.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/93.json
index 14675ea5b4c..7a01c8451f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/93.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/93.json
@@ -1 +1 @@
-{"Acute kidney injury ": 62.45208257491737}
\ No newline at end of file
+{"Asthma": 5.792623423146339, "Blood pressure increased": 5.198957911130397, "Chest discomfort": 5.198228119298911, "Drug hypersensitivity": 8.843767800274412, "Drug interaction": 7.476289550973353, "Erectile dysfunction": 30.072979219334247, "Hypertension": 4.718554198348741, "Palpitations": 3.6073794538208888, "Rash": 2.0928447175160247, "Throat tightness": 36.33814622424957, "Urticaria": 3.0349076104509365, "Wheezing": 11.781251254005566}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/930.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/930.json
index 75358b1e0fd..19c36b27872 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/930.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/930.json
@@ -1 +1 @@
-{"Anaemia ": 6.185475327070415, "Drug ineffective ": 3.3204715534382228, "Erythema ": 3.032512613042573, "Haemoglobin decreased ": 22.460361138516756, "Pruritus ": 4.010183949524811, "Therapy non-responder ": 35.2145068528249, "Urticaria ": 2.8671174536854944}
\ No newline at end of file
+{"Blood pressure decreased": 16.442521843443714, "Bradycardia": 15.877287626474516, "Cardiac arrest": 24.92043848809712, "Dizziness": 2.1413990767783457, "Dyspnoea": 2.0851332972622125, "Heart rate decreased": 69.67538769661037, "Hypotension": 5.856108939395466, "Loss of consciousness": 12.841969096643632, "Nausea": 2.33040846307821}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/931.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/931.json
index 20e02980c62..9cfae0f0586 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/931.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/931.json
@@ -1 +1 @@
-{"Cerebral haemorrhage ": 37.31248016267699, "Haemorrhage intracranial ": 141.09699798553353}
\ No newline at end of file
+{"Asthenia": 2.943466776760572, "Colorectal cancer metastatic": 397.3651147397352, "Decreased appetite": 2.071360067540176, "Diarrhoea": 2.8099440407291323, "Drug intolerance": 3.873010062679604, "Dysphonia": 5.548416506217792, "Encephalopathy": 9.23306606636068, "Gastrointestinal stromal tumour": 37.71499409464941, "General physical health deterioration": 3.087177415854483, "Hepatocellular carcinoma": 24.1944534690259, "Hypertension": 3.246565750436392, "Hypothyroidism": 5.385802107028406, "Metastases to lung": 39.116001822785215, "Mucosal inflammation": 16.534102229623297, "Oedema peripheral": 2.3459568544028206, "Off label use": 3.942849925542293, "Palmar-plantar erythrodysaesthesia syndrome": 87.94473375117687, "Platelet count decreased": 2.2626307378641197, "Product use in unapproved indication": 2.569263467385292, "Stomatitis": 9.67790234399723, "Thrombocytopenia": 2.376403706856771, "Venous thrombosis": 30.666122971379}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/932.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/932.json
index 22db467b9cb..106833b20a8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/932.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/932.json
@@ -1 +1 @@
-{"Acute respiratory failure ": 2.910069441583389, "Ankle fracture ": 2.846316494998712, "Ascites ": 2.539587105426261, "Atrial flutter ": 2.5521778269132214, "Blood creatine increased ": 5.492073195898689, "Blood disorder ": 4.327913353740692, "Blood iron decreased ": 3.646606378037705, "Blood pressure decreased ": 2.121749830671444, "Body height decreased ": 16.474720539062048, "Bronchitis ": 3.490819053410932, "Cardiac arrest ": 2.9202887497744503, "Cardiac disorder ": 8.737901114492137, "Cardiac failure ": 8.277920213256014, "Cardiac failure chronic ": 7.801808409739831, "Cardiac failure congestive ": 10.945661905532177, "Cardiac valve disease ": 7.127429426350858, "Cataract ": 3.0218606753069643, "Catheter site erythema ": 13.674166652125068, "Catheter site infection ": 13.248195541234816, "Chronic obstructive pulmonary disease ": 8.303919162191285, "Chronic respiratory failure ": 22.147652394083053, "Clostridium difficile infection ": 2.1450567238969853, "Complication associated with device ": 6.461475233805495, "Condition aggravated ": 3.4193092633835183, "Cor pulmonale ": 31.9503028950882, "Deafness ": 4.578278852315695, "Deafness bilateral ": 9.409931976434848, "Deafness unilateral ": 4.510996090418813, "Death ": 9.34331435642017, "Dermatitis contact ": 3.349191792504342, "Device related infection ": 4.758317415666881, "Disease progression ": 3.382813542148055, "Dyspnoea ": 2.8971308387304293, "Dyspnoea exertional ": 3.331870850676523, "Emphysema ": 2.874387413230555, "Epistaxis ": 2.7122332664314617, "Expired product administered ": 7.164953475073436, "Eye disorder ": 2.9090227193725964, "Eye infection ": 6.816912119640038, "Fall ": 4.239866432740998, "Fluid retention ": 20.92128598202749, "Flushing ": 2.2021747149946465, "Gallbladder disorder ": 7.465311595919974, "Gout ": 7.449146845248789, "Haemoptysis ": 2.371609943397331, "Head injury ": 3.4570171238113585, "Hepatic cirrhosis ": 2.2934915622820333, "Hip fracture ": 9.35530300055881, "Hypercapnia ": 7.790111372883434, "Hypervolaemia ": 9.17370626259317, "Hypoacusis ": 5.719086414861202, "Hypotension ": 2.6856509687232, "Hypoxia ": 6.579613087608645, "Illness ": 5.812672608819377, "Internal haemorrhage ": 3.902707183862157, "Intervertebral disc protrusion ": 2.721554729845801, "Left ventricular failure ": 10.348056324913514, "Localised infection ": 2.6587300753078886, "Lower gastrointestinal haemorrhage ": 4.3606054968789225, "Lower limb fracture ": 5.193695716837231, "Lung disorder ": 6.41020708266104, "Lung neoplasm malignant ": 3.0276096328834146, "Multiple organ dysfunction syndrome ": 2.164120203446809, "Musculoskeletal disorder ": 3.579451703223251, "Nasal congestion ": 2.088871531329061, "Neoplasm malignant ": 2.3326324008254167, "Oedema ": 3.528551314326556, "Oedema peripheral ": 2.096600197750676, "Organ failure ": 8.35955780544161, "Oxygen saturation decreased ": 5.742346903072885, "Pain in jaw ": 3.0770392163178446, "Pelvic fracture ": 5.63731821835583, "Pericardial effusion ": 4.303318454889912, "Pleural effusion ": 2.076108301167222, "Pneumonia ": 4.724835403759996, "Pre-existing condition improved ": 18.878108223792363, "Prescribed overdose ": 6.408397397325239, "Product dispensing error ": 2.405952606024619, "Product dose omission issue ": 2.535518816863075, "Product prescribing error ": 2.268025085308202, "Product use in unapproved indication ": 4.1483978827416905, "Product use issue ": 9.70986736753094, "Pulmonary arterial hypertension ": 21.9022734796344, "Pulmonary arterial pressure increased ": 53.59038141320446, "Pulmonary fibrosis ": 6.60847289045028, "Pulmonary haemorrhage ": 2.8356317966961444, "Pulmonary hypertension ": 100.21136138757144, "Pulmonary oedema ": 5.422430920585623, "Pulmonary thrombosis ": 4.929919761129982, "Raynaud's phenomenon ": 3.034748316644695, "Renal disorder ": 4.208431615015384, "Renal failure ": 2.062744533935849, "Respiratory arrest ": 2.112811488233991, "Respiratory distress ": 2.0080961425870107, "Respiratory failure ": 4.632606422577847, "Respiratory tract congestion ": 5.1630924645837615, "Right ventricular failure ": 30.143693775905938, "Scleroderma ": 31.68006842856338, "Sepsis ": 2.286742778420434, "Skin laceration ": 2.469501024733876, "Spinal fracture ": 4.019679794199031, "Sudden death ": 2.141028952056084, "Terminal state ": 21.85705375953049, "Therapeutic response unexpected ": 2.610983391234152, "Upper limb fracture ": 4.382217096822105, "Weight fluctuation ": 5.0709524258068415, "Wrist fracture ": 2.984178247355816}
\ No newline at end of file
+{"Back pain": 3.942802078297676, "Blood HIV RNA increased": 271.67295980081406, "Depression": 2.248412034285012, "Discomfort": 4.082689725855926, "Drug level decreased": 57.38686858310708, "Gait disturbance": 3.320170040198146, "Injection site pain": 13.865452540525116, "Injection site reaction": 6.399790897747688, "Injection site swelling": 3.4304522456163618, "Pain": 2.384514996026714, "Pathogen resistance": 96.76241974462664, "Viral load increased": 155.6588293864485, "Virologic failure": 251.4775160400662, "Weight increased": 2.483159975083899}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/933.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/933.json
index 7d20ca0558f..04768171cdc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/933.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/933.json
@@ -1 +1 @@
-{"Abdominal distension ": 11.63332394511703, "Abdominal pain ": 5.471351166147669, "Cholecystitis ": 36.47029122276876, "Dehydration ": 8.177235570009085, "Device related infection ": 208.10931976215815, "Intestinal obstruction ": 22.70720852555464, "Pancreatitis ": 5.047738816970853, "Renal impairment ": 2.980405636879917, "Stoma complication ": 3463.132671985337, "Vascular device infection ": 110.71144344430743, "Weight decreased ": 3.7700869099785663, "Weight increased ": 3.848072080381042}
\ No newline at end of file
+{"Ovarian hyperstimulation syndrome": 3327.7200146559853}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/934.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/934.json
index ec0ce9632ae..bcab4954b65 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/934.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/934.json
@@ -1 +1 @@
-{"Aphonia ": 70.56324565898791, "Cough ": 5.784124234146119, "Dysphonia ": 53.26779905974566, "Dyspnoea ": 2.112429277585292, "Muscle spasms ": 3.435648955674925, "Product complaint ": 50.18569025613216, "Tachycardia ": 5.822310533764407, "Vision blurred ": 5.499932006837014}
\ No newline at end of file
+{"Adrenal insufficiency": 5.57433466154503, "Ageusia": 2.821985525302036, "Anosmia": 2.091614902948057, "Aphonia": 30.49818160930581, "Arrhythmia": 4.280978231886595, "Asphyxia": 6.064662161264986, "Asthma": 6.957030332543725, "Asthmatic crisis": 30.24820815684373, "Atrial fibrillation": 2.088358708870187, "Bronchitis": 4.113702591006953, "Bronchospasm": 3.93423190087266, "Candida infection": 5.332213467043225, "Catarrh": 26.412475179229464, "Chest discomfort": 2.3078034328037025, "Choking": 2.2579712221713835, "Chondrocalcinosis pyrophosphate": 93.2131983123444, "Chronic obstructive pulmonary disease": 6.210501689746335, "Circumstance or information capable of leading to medication error": 15.403796822418244, "Condition aggravated": 2.5125567541626066, "Cortisol decreased": 15.22020898015522, "Cough": 6.894830589512865, "Diabetes insipidus": 16.066569472745726, "Drug effective for unapproved indication": 8.4967692179955, "Dry throat": 9.737700678941952, "Dysphonia": 33.776965470290435, "Dyspnoea": 2.962598123224978, "Eating disorder": 3.760359037113616, "Emphysema": 3.849993342152198, "Expired product administered": 3.996726633513987, "Extra dose administered": 4.547101710141916, "Fear": 2.53138939542242, "Foreign body in throat": 22.68240933183316, "Fungal pharyngitis": 340.2434842976009, "Gingival pain": 5.892239857535707, "Glaucoma": 7.035630884168263, "Hospitalisation": 2.98429976160136, "Ill-defined disorder": 2.138050591156522, "Intraocular pressure increased": 3.99282462525096, "Laryngeal oedema": 3.2226990820626957, "Lower respiratory tract infection": 2.415331173572774, "Lung neoplasm malignant": 2.670035907621879, "Meningitis bacterial": 78.1304303029806, "Muscle spasms": 3.5753502109139275, "Nasal congestion": 2.179668623377172, "Nasal discomfort": 7.069956232398336, "Nasopharyngitis": 3.44678315410031, "Oesophageal candidiasis": 66.56762370251242, "Oral candidiasis": 16.891231761485606, "Oral discomfort": 3.714242304878363, "Oral fungal infection": 38.85855409399144, "Oral pain": 9.450982469993644, "Oropharyngeal discomfort": 10.198770429109883, "Oropharyngeal pain": 5.2617035974429145, "Palpitations": 4.142397361176336, "Pharyngeal disorder": 17.440806358920618, "Pneumonia": 4.879631899148201, "Prinzmetal angina": 44.69007450243696, "Product complaint": 30.22467662418756, "Product dispensing error": 5.722550759897726, "Product prescribing issue": 15.576082414777268, "Product use in unapproved indication": 4.395782825017909, "Product use issue": 2.6654142874445914, "Productive cough": 11.245277341145908, "Respiratory disorder": 3.513107506681759, "Respiratory tract infection": 4.927005773753839, "Rhinitis": 5.308669703196212, "Rhinorrhoea": 4.440984642980419, "Secretion discharge": 14.596052652349638, "Sinusitis": 3.329126912064684, "Sneezing": 2.5883406083312512, "Sputum discoloured": 11.518009619141704, "Sputum increased": 14.931764189827392, "Swelling face": 2.70352315219541, "Tachycardia": 2.4550585443036885, "Taste disorder": 2.424192544424069, "Therapy cessation": 15.065164637026536, "Therapy interrupted": 9.032214630686475, "Thirst": 2.8728566195327683, "Throat irritation": 10.43334403567379, "Treatment noncompliance": 5.239383374540791, "Urinary retention": 2.5965041655489483, "Vision blurred": 2.078632902143086, "Wheezing": 5.816755531185711, "Wrong technique in device usage process": 14.33720168115818, "Wrong technique in product usage process": 3.6715627100336623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/935.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/935.json
index e769d72da34..120f0d1cde6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/935.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/935.json
@@ -1 +1 @@
-{"Acute lymphocytic leukaemia ": 15.259900200008904, "Acute myeloid leukaemia ": 10.042940838343702, "Adverse drug reaction ": 2.113249041243876, "Anaemia ": 2.378500468537065, "Atrial fibrillation ": 2.9234328772385787, "Basal cell carcinoma ": 9.633420880079411, "Blood potassium decreased ": 9.9817242664763, "Cardiac disorder ": 2.783740523035974, "Constipation ": 3.3518898502105645, "Cytopenia ": 5.002848039361536, "Deep vein thrombosis ": 2.899802729467226, "Dehydration ": 2.6501426658819045, "Diarrhoea ": 2.5010231672730545, "Disease progression ": 2.3223075201160484, "Drug hypersensitivity ": 2.41295997739638, "Drug reaction with eosinophilia and systemic symptoms ": 4.843724283090128, "Eosinophilia ": 2.187058386980683, "Fall ": 2.152795162491904, "Febrile neutropenia ": 2.7190525650161788, "Fluid retention ": 2.093020117838732, "Full blood count decreased ": 38.37444031328932, "Haemoglobin decreased ": 3.321868162017824, "Human chorionic gonadotropin increased ": 86.19494375627822, "Hypercalcaemia ": 4.231681543534475, "Immune system disorder ": 4.050934355889792, "Infection ": 2.265025484568219, "Laboratory test abnormal ": 5.466539878105095, "Mental status changes ": 2.460071258065713, "Myelodysplastic syndrome ": 18.40211469710746, "Neuropathy peripheral ": 14.733846470626007, "Neutropenia ": 2.3693134696313525, "Neutrophil count decreased ": 5.909111954859764, "Pancytopenia ": 5.8856370015526, "Plasma cell leukaemia ": 107.8712812442313, "Plasma cell myeloma ": 112.17963108683212, "Plasma cell myeloma recurrent ": 118.28309937211156, "Plasmacytoma ": 116.41884360165386, "Platelet count decreased ": 6.849828385037911, "Pneumonia ": 5.757707101418631, "Product dose omission issue ": 2.142745100089854, "Pulmonary thrombosis ": 6.99222647796845, "Rash maculo-papular ": 3.8767426990679006, "Red blood cell count decreased ": 3.9342605766055656, "Renal disorder ": 2.5355254187771683, "Renal failure ": 2.029300591031848, "Renal impairment ": 2.7229367486189404, "Sepsis ": 4.785983102001564, "Septic shock ": 2.863026399981968, "Skin cancer ": 7.364434677399502, "Spinal compression fracture ": 7.863127376414269, "Spinal fracture ": 3.4720645662000407, "Squamous cell carcinoma of skin ": 15.7859665285922, "Staphylococcal infection ": 2.1861837003579865, "Therapy non-responder ": 3.0034351129858945, "Thrombocytopenia ": 2.401947243995723, "Thrombosis ": 5.235736846282176, "Toxic skin eruption ": 2.410586752466516, "Unevaluable event ": 2.471308435465004, "White blood cell count decreased ": 5.201440902574529}
\ No newline at end of file
+{"Acute kidney injury": 9.63402865137777, "Acute myocardial infarction": 3.144398885199532, "Acute respiratory distress syndrome": 27.487064681601712, "Acute respiratory failure": 26.21272516017258, "Alanine aminotransferase increased": 24.939116223105643, "Aspartate aminotransferase increased": 14.650630310316952, "Atrial fibrillation": 2.211129101028493, "Blood alkaline phosphatase increased": 3.681850794248125, "Blood bilirubin increased": 4.2092877162199365, "Blood creatinine increased": 9.471307813523705, "Blood triglycerides increased": 9.478127597143688, "Blood urea increased": 4.539539423075138, "Bradycardia": 15.23378051477225, "COVID-19": 2.786105197517759, "COVID-19 pneumonia": 34.24699511137553, "Cardiac arrest": 9.56632911337149, "Cardio-respiratory arrest": 3.038537372321973, "Death": 8.966062108951588, "Disseminated intravascular coagulation": 8.658614844302221, "Drug-induced liver injury": 3.285597936272364, "Electrocardiogram QT prolonged": 2.6503695079183727, "Endotracheal intubation": 20.598655543198035, "Extravasation": 32.45603113180072, "General physical health deterioration": 2.354658961441206, "Glomerular filtration rate decreased": 14.218054002144711, "Hepatic enzyme increased": 9.655635216538046, "Hepatotoxicity": 3.85802291327184, "Hyperkalaemia": 2.968234979044013, "Hypertransaminasaemia": 37.78213428877549, "Hypotension": 2.9184065781608752, "Hypoxia": 11.144126444106776, "Infusion related reaction": 2.0562778267387687, "Infusion site extravasation": 58.46320675984806, "Intentional product use issue": 2.645588462887244, "International normalised ratio increased": 5.886318413113833, "Liver disorder": 2.718474235369021, "Liver function test abnormal": 5.744832301380674, "Liver function test increased": 41.3139354320268, "Maternal exposure during pregnancy": 2.5767334694179778, "Multiple organ dysfunction syndrome": 6.555047317974364, "Off label use": 2.6943899989984117, "Oxygen saturation decreased": 5.539009187792567, "Pneumonia bacterial": 18.068060823118877, "Pneumothorax": 7.598458995946239, "Prothrombin time prolonged": 22.88693871512036, "Pulseless electrical activity": 51.171587333413214, "Renal failure": 2.27938687421547, "Renal impairment": 4.579289837463883, "Respiratory disorder": 5.038094676562073, "Respiratory distress": 5.050863398594705, "Respiratory failure": 10.433139685262187, "Sepsis": 2.376132812705303, "Septic shock": 15.987080773400058, "Shock": 9.082042988590944, "Sinus bradycardia": 26.639427019983295, "Transaminases increased": 19.29736854667308}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/936.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/936.json
index 1c97cb4822f..304898bb2bd 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/936.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/936.json
@@ -1 +1 @@
-{"Aplastic anaemia ": 156.66864436367123, "Blood bilirubin increased ": 8.652710491189472, "Disease progression ": 4.600762267556851, "Haemoglobin decreased ": 5.9799112277898425, "Liver disorder ": 5.854211892527528, "Neutrophil count decreased ": 8.744216240321132, "Platelet count decreased ": 23.83967818532781, "Product use in unapproved indication ": 11.81408139759398, "Renal impairment ": 5.121604841723337, "Therapeutic product effect incomplete ": 5.53348925887042, "Thrombocytopenia ": 3.175636802090408, "White blood cell count decreased ": 8.223192164994446}
\ No newline at end of file
+{"Abdominal abscess": 18.45552283424037, "Abortion spontaneous": 2.574659936184966, "Abscess": 7.407814955138795, "Acute myeloid leukaemia": 2.6111007580044947, "Adverse drug reaction": 2.345376446178961, "Adverse event": 2.713879902384888, "Anal abscess": 17.075151057943053, "Basal cell carcinoma": 3.829716901860913, "Bronchitis": 2.550155345312408, "Candida infection": 2.725382264414404, "Cellulitis": 5.536573011993927, "Cholelithiasis": 2.478143464855872, "Clostridium difficile infection": 3.744381497287317, "Colitis ulcerative": 15.222058121390804, "Colon cancer": 5.5959722442554165, "Crohn's disease": 18.39925018668703, "Cystitis": 2.0708954514278317, "Cytomegalovirus enterocolitis": 49.43171692235907, "Cytomegalovirus infection": 3.9752503136806094, "Disseminated tuberculosis": 39.76308857374054, "Diverticulitis": 2.2147523230037782, "Drug hypersensitivity": 3.0077923101163946, "Drug level decreased": 7.475170415621323, "Enterobacter infection": 36.44380738892816, "Exposure during pregnancy": 6.181953327635476, "Failed induction of labour": 220.88952195431392, "Fistula": 12.746539596079325, "Flushing": 3.471249105880754, "Foetal exposure during pregnancy": 2.762625401323441, "Frequent bowel movements": 8.053457801901756, "Fungal infection": 3.5226170216749817, "Gastroenteritis viral": 6.332296606166667, "Haematochezia": 3.286141358476609, "Hidradenitis": 19.43885152314032, "IgA nephropathy": 23.15832860750893, "Ileus": 3.4049528078020925, "Infusion related reaction": 22.42866634364605, "Interstitial lung disease": 4.998677637530943, "Intestinal obstruction": 3.091521165483192, "Limb injury": 3.016224518745656, "Lupus-like syndrome": 28.574480290719137, "Lymphoma": 6.610938415455175, "Malignant melanoma": 4.181793079487493, "Mass": 3.500942397417381, "Multiple sclerosis": 2.0102165199118067, "Neutropenia neonatal": 151.82492576238687, "Off label use": 2.217596738602733, "Omphalitis": 242.94778403433585, "Peritonitis": 4.382928698491725, "Pneumocystis jirovecii pneumonia": 12.211236564333936, "Pneumonia": 2.6648055836899176, "Premature baby": 7.191025423228614, "Premature delivery": 5.77335135299074, "Product use issue": 3.3670458877486507, "Pseudomonas infection": 6.979032959489842, "Psoriasis": 4.663771121219916, "Pulmonary tuberculosis": 12.228488732351382, "Pyelonephritis": 4.266567860485032, "Rheumatoid arthritis": 2.548970405139753, "Secretion discharge": 6.028913191362397, "Sinusitis": 2.410440625364954, "Skin laceration": 4.823626113905671, "Squamous cell carcinoma": 6.967829054857897, "Staphylococcal infection": 6.504771481085286, "Stillbirth": 9.257644931739534, "Subarachnoid haemorrhage": 3.7503765050725537, "Therapeutic product effect decreased": 2.918867482077456, "Therapeutic product effect incomplete": 2.1204925997415667, "Therapeutic response decreased": 4.515607138305059, "Threatened labour": 66.66758236181866, "Tuberculosis": 8.442488129413855, "Urinary tract infection": 2.24982565931803, "Vasculitis": 2.9211708371701763, "White blood cell count increased": 2.4305358712559992}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/937.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/937.json
index a70453a85fb..d4bd0dfe6a9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/937.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/937.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 5.654078537973878, "Acute kidney injury ": 4.136837875356084, "Adverse event ": 4.36861513039756, "Alanine aminotransferase increased ": 2.3407995353814126, "Aspartate aminotransferase increased ": 2.1683863683698887, "Blood alkaline phosphatase increased ": 2.1974001787726, "Blood bilirubin increased ": 29.99183083400323, "Blood bilirubin unconjugated increased ": 91.59487959699156, "Blood creatine phosphokinase increased ": 2.505911739982772, "Blood creatinine increased ": 4.057703972461057, "Blood triglycerides increased ": 4.994795360898335, "Caesarean section ": 59.272017959283446, "Calculus urinary ": 184.74203164834915, "Cholecystitis ": 12.233773176654251, "Cholecystitis acute ": 17.147099570275603, "Cholelithiasis ": 29.8601114088961, "Cholestasis ": 3.2666343409498584, "Cushing's syndrome ": 14.802245477305148, "Diabetes mellitus ": 2.6803133827910326, "Drug interaction ": 2.584605496894881, "Drug resistance ": 10.274192212131634, "Dysphagia ": 2.4733034096747586, "Electrocardiogram QT prolonged ": 3.1487332357555164, "Fanconi syndrome ": 34.118770278916884, "Fanconi syndrome acquired ": 19.91945074203826, "Foetal exposure during pregnancy ": 3.1554473041098103, "Gamma-glutamyltransferase increased ": 2.030095205158305, "Gastrointestinal tube insertion ": 25.148317704360064, "Glomerular filtration rate decreased ": 4.208226432560288, "Gynaecomastia ": 9.93630983269045, "Haematuria ": 2.217126970452264, "Hepatic cirrhosis ": 3.768678234504326, "Hepatic cytolysis ": 14.384184440457895, "Hepatic steatosis ": 3.8311509001919695, "Hepatitis ": 7.748112676319753, "Hepatitis C ": 3.097400349434636, "Hepatitis acute ": 7.743430362215176, "Hepatotoxicity ": 3.263681494975544, "Hip fracture ": 4.0953973062765305, "Hydronephrosis ": 13.064552364159002, "Hyperbilirubinaemia ": 98.03927409503956, "Jaundice ": 56.45262549599393, "Lipoatrophy ": 72.72424495166167, "Lipodystrophy acquired ": 45.35792210685551, "Live birth ": 17.04406533358518, "Liver function test abnormal ": 2.58293801683463, "Maternal exposure during pregnancy ": 5.0191106146855775, "Nephrolithiasis ": 95.4946524093281, "Normal newborn ": 47.3521230043124, "Ocular icterus ": 162.10864387129527, "Osteonecrosis ": 3.5002651700339324, "Pancreatitis ": 5.913890930661339, "Pancreatitis acute ": 3.938583819082288, "Polyneuropathy ": 6.777430396939882, "Pregnancy ": 31.21522719821035, "Proteinuria ": 2.8791696134844176, "Renal colic ": 435.5994258054364, "Renal failure ": 2.8103017615482604, "Renal impairment ": 2.4096596663372702, "Renal pain ": 3.8921833196092233, "Renal tubular necrosis ": 7.764222364023111, "Transaminases increased ": 8.08996473059249, "Twin pregnancy ": 127.26107473158744, "Ventricular tachycardia ": 3.6456469519206514, "Viral load increased ": 38.12423962785753, "Weight increased ": 2.414749165524713, "Yellow skin ": 9.993287100285988}
\ No newline at end of file
+{"Abdominal pain": 6.064764127533578, "Abdominal pain upper": 2.6714991153295933, "Condition aggravated": 3.03605788152068, "Defaecation urgency": 138.6835707644756, "Diarrhoea": 4.914686856072868, "Flatulence": 18.668820306514707, "Frequent bowel movements": 24.48324583090658, "Haematochezia": 22.429862933830425, "Infection": 3.401989397300177, "Intentional dose omission": 161.68423900628736, "Intentional product use issue": 9.529521865024185, "Lower respiratory tract infection": 38.60930812577993, "Mucous stools": 230.5545196447674, "Oropharyngeal pain": 3.1328507814803235, "Product dose omission issue": 4.1373207573419375, "Stress": 19.057788030558893, "Weight decreased": 8.422461160119319, "Weight increased": 13.87420717167038}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/938.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/938.json
index 8dfffbcb232..1b876b89d72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/938.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/938.json
@@ -1 +1 @@
-{"Diarrhoea ": 2.5036642626190755, "Drug interaction ": 6.067452934974008}
\ No newline at end of file
+{"Dermatitis contact": 352.636519738192, "Drug ineffective": 2.46561935359564, "Eosinophilia": 31.80448542443745, "Medical device site reaction": 51920.25683250734, "Muscle rigidity": 157.05964573374231, "Muscle spasticity": 228.3595787715261, "Musculoskeletal stiffness": 25.34841798684741, "Pallor": 55.625400002667504, "Rash erythematous": 15.011186979440405, "Renal failure": 4.79618968911098, "Scab": 284.7009139956396, "Skin atrophy": 569.6801783734003, "Skin exfoliation": 60.35200244047112, "Skin haemorrhage": 300.7692327937437, "Skin plaque": 346.5218211341869}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/939.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/939.json
index 82cbff0f4f3..b1dea891994 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/939.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/939.json
@@ -1 +1 @@
-{"Affective disorder ": 2.300511666048243, "Anaemia ": 13.720636164537844, "Anal pruritus ": 9.494457793957295, "Anorectal discomfort ": 6.377334237445123, "Anorectal disorder ": 9.232428133105154, "Aplasia pure red cell ": 27.072688433532356, "Ascites ": 8.615231177692301, "Autoimmune haemolytic anaemia ": 3.329684294857318, "Autoimmune hepatitis ": 4.282821429664738, "Blood bilirubin increased ": 5.363175651413097, "Bone marrow failure ": 2.937554684951757, "Chronic hepatitis C ": 21.21490797082938, "Cryoglobulinaemia ": 40.89345089828407, "Cutaneous sarcoidosis ": 49.87616868919748, "Depression ": 2.288724542443676, "Depressive symptom ": 4.092827579778238, "Dermatitis ": 3.1163940801727037, "Drug ineffective ": 13.123138500513036, "Drug reaction with eosinophilia and systemic symptoms ": 2.9907391295144867, "Encephalopathy ": 3.523350458763207, "Gastric varices ": 38.79697485049733, "Genotype drug resistance test positive ": 69.62172040059913, "Granulocytopenia ": 2.226818705440337, "Graves' disease ": 7.182308576945927, "Haemoglobin abnormal ": 5.890354563154924, "Haemoglobin decreased ": 7.043508002422353, "Haemolysis ": 15.752057155528544, "Haemolytic anaemia ": 16.574781536664425, "Hepatic cancer ": 7.509593228685498, "Hepatic cirrhosis ": 18.211423949475275, "Hepatic encephalopathy ": 15.927670214224351, "Hepatic failure ": 7.293326038199944, "Hepatic fibrosis ": 8.477722510818781, "Hepatic lesion ": 5.493003906844376, "Hepatitis B reactivation ": 14.056526656310446, "Hepatitis C ": 298.6586198673844, "Hepatitis C RNA increased ": 90.82319023474894, "Hepatitis C RNA positive ": 204.29920361086772, "Hepatitis C virus test positive ": 208.4716387124404, "Hepatitis E ": 23.013618978041563, "Hepatocellular carcinoma ": 21.61363963307781, "Hyperbilirubinaemia ": 9.310040241056877, "Hypocalcaemia ": 7.493382316681053, "Hypomagnesaemia ": 12.208683398658328, "Immune system disorder ": 2.439683977107897, "Immune thrombocytopenia ": 2.3115701136270284, "Jaundice ": 3.4760911986690397, "Leukopenia ": 3.0724237219492827, "Liver transplant ": 23.68568270437797, "Liver transplant rejection ": 12.654757578857504, "Lymphopenia ": 3.032454403605515, "Mania ": 2.823502289625839, "Mental status changes ": 2.2090090052939235, "Mitochondrial toxicity ": 11.496602397107832, "Oesophageal varices haemorrhage ": 26.03871474924258, "Pancytopenia ": 2.9024323561220244, "Paranoia ": 2.147162603587857, "Pathogen resistance ": 3.805979651383172, "Personality change ": 2.737295244151301, "Polydipsia ": 3.9943487712233257, "Polyuria ": 2.3949521372821843, "Porphyria non-acute ": 28.203000947941906, "Portal hypertension ": 8.161965845362309, "Portal vein thrombosis ": 11.541880933481238, "Proctalgia ": 4.497240026359802, "Product use issue ": 2.106283945635109, "Psychotic disorder ": 3.5022921063778685, "Pulmonary arterial hypertension ": 2.3689584657338605, "Red blood cell count decreased ": 2.548765900302668, "Remission not achieved ": 59.43979644407972, "Renal impairment ": 2.952741410901281, "Retinopathy ": 9.647398177445456, "Sarcoidosis ": 35.234136354622734, "Skin fissures ": 3.4608382545625664, "Skin laceration ": 3.022576464560005, "Spontaneous bacterial peritonitis ": 21.08094225289485, "Therapy cessation ": 3.754166716740325, "Therapy non-responder ": 4.367961425666942, "Transfusion ": 6.069081172467718, "Treatment failure ": 30.163825690657102, "Treatment noncompliance ": 3.250176080624052, "Type 1 diabetes mellitus ": 3.659968100447061, "Unevaluable event ": 3.18860014779985, "Varices oesophageal ": 13.629255882454062, "Viral load increased ": 13.45464430674092, "Viral mutation identified ": 28.356824525381988, "Virologic failure ": 62.376829354287736}
\ No newline at end of file
+{"Acute kidney injury": 2.3388852017317108, "Altered state of consciousness": 5.84545652419119, "Blood glucose decreased": 5.147961219419824, "Blood glucose increased": 2.940196085464504, "Depressed level of consciousness": 3.56984247287949, "Drug interaction": 8.326404360676671, "Glycosylated haemoglobin increased": 10.050717719234516, "Hyperglycaemia": 4.522722420950192, "Hyperkalaemia": 5.778444635114419, "Hypoglycaemia": 71.80241591451644, "Hypoglycaemic coma": 74.39386919495901, "Inappropriate schedule of product administration": 3.0792771849677902, "Lactic acidosis": 20.635407602360583, "Loss of consciousness": 2.57261559484694, "Medication error": 17.68794989665085, "Metabolic acidosis": 11.586812331360129, "Myoclonus": 12.87899500681118, "Pancreatitis acute": 5.093129475791856, "Sopor": 44.78243475853676}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/94.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/94.json
index a42250ce6dc..145ee3a3107 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/94.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/94.json
@@ -1 +1 @@
-{"Completed suicide ": 158.5298852551079}
\ No newline at end of file
+{"Completed suicide": 264.4547767318826}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/940.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/940.json
index 475ac26954e..6b9861ad10b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/940.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/940.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 8.865599627801314, "Anaemia ": 2.652907608378116, "Aspartate aminotransferase increased ": 9.142394708369558, "Blood alkaline phosphatase increased ": 4.309969433314161, "Blood bilirubin increased ": 4.362074356800702, "Blood creatinine increased ": 2.0874397691908726, "Bone lesion ": 106.27735925697556, "Bone pain ": 2.2162236238182427, "Breast cancer ": 11.848224408275744, "Breast cancer metastatic ": 106.076078243657, "Breast cancer recurrent ": 24.06288820845183, "Breast mass ": 36.2931240431416, "Carbohydrate antigen 15-3 increased ": 358.6665543722972, "Carcinoembryonic antigen increased ": 39.950177391668255, "Disease progression ": 3.5577342865313857, "Electrocardiogram QT prolonged ": 19.127989752419097, "Febrile neutropenia ": 2.6518169682372834, "Gamma-glutamyltransferase increased ": 3.1493419256252144, "Granulocytopenia ": 6.4494456038953, "Haematocrit decreased ": 4.957351605025616, "Haematotoxicity ": 19.478325362592496, "Haemoglobin decreased ": 3.207140828356476, "Hepatic enzyme increased ": 2.888928198072392, "Hepatic failure ": 3.4202275596948484, "Hepatic lesion ": 24.1811488612435, "Hepatic steatosis ": 3.3403508294835342, "Hepatitis ": 2.631150189797532, "Hepatotoxicity ": 42.37642320431733, "Hormone receptor positive HER2 negative breast cancer ": 739.6284857264747, "Hot flush ": 2.758221051930096, "Hypertransaminasaemia ": 14.751527832335034, "Leukopenia ": 15.258175669243291, "Liver function test increased ": 3.722892574065247, "Liver injury ": 2.180673050781036, "Malignant neoplasm progression ": 17.327820122738164, "Metastases to bone ": 77.19685287946722, "Metastases to central nervous system ": 6.822928870819823, "Metastases to liver ": 44.954693367645305, "Metastases to lung ": 36.50779916579864, "Metastases to lymph nodes ": 40.90150870083818, "Metastases to pleura ": 69.54439858823935, "Metastases to spine ": 37.56694829658316, "Metastasis ": 18.504186471736244, "Neutropenia ": 38.78440878646156, "Neutrophil count decreased ": 6.38435292781037, "PIK3CA-activated mutation ": 139.72286085065116, "Pleural effusion ": 4.336217119998718, "Pneumonitis ": 4.221716719579039, "Pulmonary mass ": 5.1817882879946335, "Skin toxicity ": 10.701557439940547, "Therapeutic response decreased ": 2.8099632725825394, "Therapy partial responder ": 45.722913034238296, "Thrombocytopenia ": 2.557097466119405, "Transaminases increased ": 5.982256929761117, "Tumour marker increased ": 18.321001091922437, "Vitiligo ": 31.45282931179806, "White blood cell count decreased ": 5.349684788091665}
\ No newline at end of file
+{"Back pain": 2.934197525506811, "Myalgia": 2.185215636451157}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/941.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/941.json
index 57bac946c7a..4dadc69d91d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/941.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/941.json
@@ -1 +1 @@
-{"Adverse reaction ": 52.27602465770154, "Agranulocytosis ": 7.717355657915041, "Amyotrophic lateral sclerosis ": 287.1360725659436, "Angioedema ": 2.397005643615922, "C-reactive protein increased ": 5.569495621042735, "Condition aggravated ": 2.529703687805848, "Death ": 4.225347330789885, "Disease progression ": 19.985820636324505, "Dysphagia ": 10.107918984872065, "Gastric fistula ": 847.6445785237527, "Hepatic enzyme increased ": 2.8071925575445054, "Interstitial lung disease ": 10.14147402809956, "Motor neurone disease ": 1354.1392518161315, "Oxygen saturation decreased ": 4.895565807919141, "Pancreatitis ": 6.768214897223107, "Pancreatitis acute ": 12.25409631709886, "Renal impairment ": 2.1193589760876006, "Respiratory failure ": 3.7773754379097406, "Speech disorder ": 8.068271285287935}
\ No newline at end of file
+{"Anaemia": 6.185475327070415, "Drug ineffective": 3.3204470079525183, "Erythema": 3.032482954512945, "Haemoglobin decreased": 22.460361138516756, "Pruritus": 4.010135376529856, "Therapy non-responder": 35.21142919167831, "Urticaria": 2.8670880815231747}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/942.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/942.json
index c1412653706..c2b0ed56229 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/942.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/942.json
@@ -1 +1 @@
-{"Condition aggravated ": 2.104734489129125, "Death ": 17.58785499525715, "Disease progression ": 10.671788302266242, "Drug interaction ": 2.727567420568221, "Gastrointestinal disorder ": 4.771925269578914, "Interstitial lung disease ": 11.600384773928296, "Pancreatitis acute ": 15.922121402782386}
\ No newline at end of file
+{"Cerebral haemorrhage": 37.31248016267699, "Haemorrhage intracranial": 141.09699798553353}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/943.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/943.json
index 638c15ca9c4..8bfefa7eea7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/943.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/943.json
@@ -1 +1 @@
-{"Abnormal weight gain ": 6.005971472584468, "Abortion induced ": 2.4732068224866106, "Abscess ": 2.276288007385868, "Acne ": 49.621101479197925, "Adenocarcinoma of colon ": 8.737161144514905, "Adverse drug reaction ": 4.229208421116481, "Alanine aminotransferase increased ": 2.3136299291816167, "Alopecia areata ": 3.372158443839574, "Ankle fracture ": 2.066262241425713, "Ankylosing spondylitis ": 2.816111474897571, "Aphthous ulcer ": 4.783314784655471, "Arthritis ": 3.250936412412874, "Arthritis bacterial ": 3.678470300077306, "Autoimmune disorder ": 2.607852776472039, "Basal cell carcinoma ": 3.5212538288788267, "Blood cholesterol increased ": 5.8492789731362, "Blood creatine phosphokinase increased ": 9.48199002843258, "Blood iron decreased ": 3.957637095227268, "Blood triglycerides increased ": 6.250642925383463, "Breast cancer female ": 11.749656230069142, "C-reactive protein increased ": 3.308175966140888, "Cellulitis ": 2.463731447863826, "Cerebrovascular accident ": 2.494039019276256, "Clostridium difficile infection ": 2.665947935295035, "Colectomy ": 17.32529223965676, "Colitis ischaemic ": 2.001933340200184, "Colitis ulcerative ": 7.013436005506558, "Colon cancer ": 2.843256549723816, "Coronavirus infection ": 10.883178419716408, "Crohn's disease ": 3.5153066016908654, "Cutaneous T-cell lymphoma ": 20.339623801921945, "Cytomegalovirus colitis ": 8.032653373812398, "Cytomegalovirus infection ": 2.3235527049488804, "Deep vein thrombosis ": 4.713727064858936, "Dermatitis acneiform ": 12.996695656558094, "Dermatitis atopic ": 76.47226426717344, "Diverticulitis ": 5.199960889352604, "Diverticulitis intestinal perforated ": 95.70263287671716, "Diverticulum ": 2.5944385848836133, "Diverticulum intestinal haemorrhagic ": 6.458060957101545, "Eczema ": 3.2567135673373167, "Eczema herpeticum ": 258.34599891787883, "Embolism ": 4.760004513842372, "Embolism venous ": 15.404675622541552, "Erysipelas ": 4.368873185481797, "Erythema nodosum ": 3.333841955523747, "Faecal calprotectin increased ": 23.452166121700063, "Folliculitis ": 4.6578291969573975, "Foot deformity ": 2.1604749295277226, "Foot operation ": 5.491155492377541, "Frequent bowel movements ": 3.701705741691852, "Frustration tolerance decreased ": 2.611825415051352, "Furuncle ": 5.102242323332209, "Gastrointestinal perforation ": 25.263895824690486, "General symptom ": 11.243500433951178, "Genital herpes ": 19.003009222257848, "Genital herpes zoster ": 70.67250293088274, "Gingival pain ": 6.82892240979074, "Haematocrit decreased ": 2.144471334451928, "Hepatitis B ": 3.8459932689346337, "Hepatitis E ": 20.70950238902325, "Herpes ophthalmic ": 36.00855282893569, "Herpes simplex ": 17.119894279312625, "Herpes virus infection ": 21.3461419727408, "Herpes zoster ": 10.37854035603726, "Herpes zoster disseminated ": 15.486438901225457, "High density lipoprotein increased ": 23.937290253463665, "Hordeolum ": 11.39450420949474, "Hypercholesterolaemia ": 5.744124232022465, "Ileostomy ": 45.64470545883065, "Immunodeficiency ": 4.524245392290687, "Immunosuppression ": 8.604682647038587, "Impetigo ": 19.33030849576726, "Infection ": 2.3340980809170984, "Inflammation ": 2.6446323869119075, "Inflammatory bowel disease ": 4.429214628484195, "Inflammatory marker increased ": 3.874335321154836, "Intervertebral disc protrusion ": 2.8548079335450582, "Intestinal perforation ": 6.048539483244509, "Joint arthroplasty ": 14.761714643336084, "Joint dislocation ": 3.87826984792312, "Joint effusion ": 3.820260722652491, "Joint lock ": 11.360775186187848, "Joint swelling ": 2.332162037565584, "Knee arthroplasty ": 2.4267527637859208, "Knee operation ": 14.051546388580569, "Laboratory test abnormal ": 3.9547856204719793, "Large intestine perforation ": 3.1395876477275526, "Lichenification ": 34.57120774683536, "Lipids increased ": 25.13823522661907, "Liver abscess ": 5.309696110515334, "Liver function test increased ": 3.485373640472775, "Loss of therapeutic response ": 12.81877212950778, "Low density lipoprotein increased ": 33.65583573680853, "Lung neoplasm malignant ": 2.745309089353502, "Lung opacity ": 4.900077487906754, "Lymphocyte count decreased ": 2.376827763762872, "Lymphocyte count increased ": 5.071809767424735, "Lymphoma ": 5.861253074952829, "Lymphopenia ": 3.80303966770919, "Malabsorption ": 5.98398775184608, "Malignant melanoma ": 3.870643412967511, "Meningitis ": 3.885957320941921, "Middle insomnia ": 3.581925439903827, "Mobility decreased ": 2.138089171974596, "Mouth ulceration ": 2.082510743071653, "Musculoskeletal disorder ": 4.766405364026517, "Neoplasm malignant ": 2.233107415963276, "Nerve compression ": 3.7905352177558, "Neuroendocrine carcinoma of the skin ": 27.869252458487264, "Ophthalmic herpes zoster ": 9.899244154207254, "Oral candidiasis ": 2.5810019956608703, "Oral herpes ": 10.802274084733094, "Organising pneumonia ": 2.4237319910097623, "Osteoarthritis ": 2.8362530455011776, "Ostomy bag placement ": 441.3242238122656, "Overweight ": 3.681188859816153, "Pain of skin ": 2.364682603535332, "Papilloma viral infection ": 6.841144726359089, "Papule ": 2.0767886461909986, "Phlebitis ": 4.018172399913326, "Platelet count increased ": 4.8985689135926105, "Pneumocystis jirovecii pneumonia ": 9.514856509044794, "Pneumonia bacterial ": 3.905681666530848, "Polyarthritis ": 3.702505109587792, "Portal vein thrombosis ": 4.602849813601846, "Post herpetic neuralgia ": 3.496675873382596, "Post procedural complication ": 2.96557265258614, "Post procedural infection ": 5.919483272612193, "Product residue present ": 50.648782418079904, "Psoriasis ": 3.5421088835381243, "Psoriatic arthropathy ": 3.210766460606365, "Pulmonary embolism ": 7.159614062367764, "Pulmonary thrombosis ": 3.5624446881862863, "Purulent discharge ": 6.360660905819318, "Pustule ": 8.548560022045779, "Rash pustular ": 5.641788329028064, "Red blood cell sedimentation rate increased ": 2.4447904677894483, "Respiratory tract infection ": 4.934694337120175, "Retinal artery occlusion ": 3.309424599762452, "Retinal detachment ": 2.407278713548162, "Retinal vein occlusion ": 5.941969111206735, "Rheumatic disorder ": 6.098823659678434, "Rheumatoid arthritis ": 7.204183789109653, "Rosacea ": 29.57627113436828, "Scab ": 2.038828821780289, "Semen discolouration ": 289.0849879776245, "Skin cancer ": 3.940254848627724, "Skin disorder ": 4.212365609405509, "Skin lesion ": 3.20011956906552, "Skin plaque ": 4.707851274598522, "Sluggishness ": 2.085762982981905, "Spinal compression fracture ": 2.403045118314476, "Spinal fracture ": 2.7059764409540894, "Spinal operation ": 5.40908461664921, "Spinal pain ": 2.1086057426790688, "Spinal stenosis ": 2.9068184478525096, "Squamous cell carcinoma ": 2.952690517913461, "Squamous cell carcinoma of skin ": 6.275978905977544, "Subcutaneous abscess ": 4.220845161687265, "Superficial vein thrombosis ": 2.486406732099631, "Superinfection ": 11.26687674351851, "Surgery ": 3.3347755421198317, "Suspected COVID-19 ": 2.5153569406371306, "Synovitis ": 4.321514368197263, "Therapeutic product effect decreased ": 4.722361518391275, "Therapeutic product effect incomplete ": 4.442196321109064, "Therapeutic response shortened ": 4.188111256097998, "Thrombosis ": 3.384953273007905, "Tongue neoplasm malignant stage unspecified ": 14.0273953179269, "Tonsillitis ": 3.632839904345888, "Tooth abscess ": 2.9059059122796618, "Transaminases increased ": 3.353007119714836, "Tuberculosis ": 4.998170287611517, "Ulcer ": 5.353798710246716, "Unevaluable event ": 6.675917046014343, "Upper respiratory tract infection ": 2.8972700512679066, "Varicella zoster virus infection ": 9.929327595907507, "Venous thrombosis ": 3.066795475760269, "Venous thrombosis limb ": 7.655034469053054, "Vitamin D decreased ": 4.118669329111923, "Vulvovaginal mycotic infection ": 3.221663923383557, "Weight increased ": 5.827381934297904}
\ No newline at end of file
+{"Acute respiratory failure": 2.910069441583389, "Ankle fracture": 2.846316494998712, "Ascites": 2.539587105426261, "Atrial flutter": 2.5521778269132214, "Blood creatine increased": 5.492073195898689, "Blood disorder": 4.327913353740692, "Blood iron decreased": 3.646606378037705, "Blood pressure decreased": 2.1216808747662625, "Body height decreased": 16.474720539062048, "Bronchitis": 3.490609259407106, "Cardiac arrest": 2.9202887497744503, "Cardiac disorder": 8.737901114492137, "Cardiac failure": 8.277160020445193, "Cardiac failure chronic": 7.801808409739831, "Cardiac failure congestive": 10.944827477488472, "Cardiac valve disease": 7.127429426350858, "Cataract": 3.0218606753069643, "Catheter site erythema": 13.674166652125068, "Catheter site infection": 13.248195541234816, "Chronic obstructive pulmonary disease": 8.303919162191285, "Chronic respiratory failure": 22.147652394083053, "Clostridium difficile infection": 2.1450567238969853, "Complication associated with device": 6.461475233805495, "Condition aggravated": 3.4193092633835183, "Cor pulmonale": 31.9503028950882, "Deafness": 4.578278852315695, "Deafness bilateral": 9.409931976434848, "Deafness unilateral": 4.510996090418813, "Death": 9.34331435642017, "Dermatitis contact": 3.349191792504342, "Device related infection": 4.758317415666881, "Disease progression": 3.382813542148055, "Dyspnoea": 2.8970877076711234, "Dyspnoea exertional": 3.331870850676523, "Emphysema": 2.874387413230555, "Epistaxis": 2.7122332664314617, "Expired product administered": 7.164953475073436, "Eye disorder": 2.9090227193725964, "Eye infection": 6.816912119640038, "Fall": 4.239757413799065, "Fluid retention": 20.92128598202749, "Flushing": 2.2021747149946465, "Gallbladder disorder": 7.465311595919974, "Gout": 7.449146845248789, "Haemoptysis": 2.371609943397331, "Head injury": 3.4570171238113585, "Hepatic cirrhosis": 2.2934915622820333, "Hip fracture": 9.35530300055881, "Hypercapnia": 7.790111372883434, "Hypervolaemia": 9.17370626259317, "Hypoacusis": 5.718603293175185, "Hypotension": 2.6855887632287057, "Hypoxia": 6.579613087608645, "Illness": 5.812672608819377, "Internal haemorrhage": 3.902707183862157, "Intervertebral disc protrusion": 2.721554729845801, "Left ventricular failure": 10.348056324913514, "Localised infection": 2.6587300753078886, "Lower gastrointestinal haemorrhage": 4.3606054968789225, "Lower limb fracture": 5.193695716837231, "Lung disorder": 6.41020708266104, "Lung neoplasm malignant": 3.0276096328834146, "Multiple organ dysfunction syndrome": 2.164120203446809, "Musculoskeletal disorder": 3.578501469580054, "Nasal congestion": 2.088871531329061, "Neoplasm malignant": 2.3326324008254167, "Oedema": 3.528551314326556, "Oedema peripheral": 2.096548311481248, "Organ failure": 8.35955780544161, "Oxygen saturation decreased": 5.742038399604779, "Pain in jaw": 3.0770392163178446, "Pelvic fracture": 5.63731821835583, "Pericardial effusion": 4.303318454889912, "Pleural effusion": 2.07591690630258, "Pneumonia": 4.724835403759996, "Pre-existing condition improved": 18.878108223792363, "Prescribed overdose": 6.408397397325239, "Product dispensing error": 2.405952606024619, "Product dose omission issue": 2.535518816863075, "Product prescribing error": 2.268025085308202, "Product use in unapproved indication": 4.148268128937778, "Product use issue": 9.70986736753094, "Pulmonary arterial hypertension": 21.9022734796344, "Pulmonary arterial pressure increased": 53.59038141320446, "Pulmonary fibrosis": 6.60847289045028, "Pulmonary haemorrhage": 2.8356317966961444, "Pulmonary hypertension": 100.21136138757144, "Pulmonary oedema": 5.421716243309108, "Pulmonary thrombosis": 4.929919761129982, "Raynaud's phenomenon": 3.034748316644695, "Renal disorder": 4.207809029190544, "Renal failure": 2.062744533935849, "Respiratory arrest": 2.112811488233991, "Respiratory distress": 2.0080961425870107, "Respiratory failure": 4.63222267073336, "Respiratory tract congestion": 5.1630924645837615, "Right ventricular failure": 30.143693775905938, "Scleroderma": 31.68006842856338, "Sepsis": 2.286742778420434, "Skin laceration": 2.469501024733876, "Spinal fracture": 4.019679794199031, "Sudden death": 2.141028952056084, "Terminal state": 21.85705375953049, "Therapeutic response unexpected": 2.610983391234152, "Upper limb fracture": 4.382217096822105, "Weight fluctuation": 5.0709524258068415, "Wrist fracture": 2.984178247355816}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/944.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/944.json
index 709672769db..de44d52cd99 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/944.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/944.json
@@ -1 +1 @@
-{"Bradycardia ": 17.29285774469415, "Condition aggravated ": 9.511550497386043, "Dyspnoea exertional ": 40.80273422367407, "Hypotension ": 8.0888185020458, "Left-to-right cardiac shunt ": 20394.860412082395, "Pulmonary hypertension ": 102.00807033669888, "Therapeutic product effect incomplete ": 20.75869366568164, "Vascular resistance pulmonary decreased ": 79946.97217693867}
\ No newline at end of file
+{"Abdominal distension": 11.63332394511703, "Abdominal pain": 5.471351166147669, "Cholecystitis": 36.47029122276876, "Dehydration": 8.176799027488995, "Device related infection": 208.10931976215815, "Intestinal obstruction": 22.70720852555464, "Pancreatitis": 5.047738816970853, "Renal impairment": 2.980405636879917, "Stoma complication": 3463.132671985337, "Vascular device infection": 110.71144344430743, "Weight decreased": 3.7700869099785663, "Weight increased": 3.848072080381042}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/945.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/945.json
index e7f03407f74..1b5ffab9a45 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/945.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/945.json
@@ -1 +1 @@
-{"Crohn's disease ": 54.517793726689206, "Drug ineffective ": 2.0670720124293824, "Off label use ": 12.406339922583518, "Psoriasis ": 64.94692932419719, "Psoriatic arthropathy ": 24.8556723405198}
\ No newline at end of file
+{"Aphonia": 70.56324565898791, "Cough": 5.7840705831461925, "Dysphonia": 53.26779905974566, "Dyspnoea": 2.112397895044784, "Muscle spasms": 3.435648955674925, "Product complaint": 50.18569025613216, "Tachycardia": 5.822163387844451, "Vision blurred": 5.499932006837014}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/946.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/946.json
index 011a53b95ba..f4cae9cd6c9 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/946.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/946.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 7.068079384800062, "Acute psychosis ": 17.990680499979902, "Adverse drug reaction ": 3.012132011989039, "Aggression ": 4.053013405625042, "Agitation ": 5.633948181427527, "Akathisia ": 5.32539636822857, "Alanine aminotransferase increased ": 2.106335512013991, "Aspartate aminotransferase increased ": 2.868585812657826, "Asphyxia ": 7.301962654714328, "Ataxia ": 5.013150284737163, "Blood creatine phosphokinase increased ": 3.7414610368613226, "Blood prolactin increased ": 22.948509763138265, "Bradykinesia ": 16.140439068982165, "Brain injury ": 6.020931689875798, "Catatonia ": 22.139566954908773, "Circulatory collapse ": 2.420592657576212, "Cognitive disorder ": 2.2310978319221086, "Confusional state ": 3.192707645869039, "Cyanosis ": 3.040803128395842, "Delirium ": 3.1082039489478555, "Dementia ": 2.26469208410736, "Depressed level of consciousness ": 14.849125585452851, "Drug interaction ": 8.208174958199752, "Drug level increased ": 2.6775494459026072, "Dysarthria ": 4.998529316077903, "Dyskinesia ": 3.3110846549008937, "Dystonia ": 11.700979329501202, "Emotional disorder ": 6.337126418785396, "Encephalopathy ": 4.175079612766444, "Extrapyramidal disorder ": 35.78011921299647, "Feeling abnormal ": 3.492269262438848, "Galactorrhoea ": 10.581923308275991, "Generalised tonic-clonic seizure ": 2.0941628084335417, "Gynaecomastia ": 14.851192660703886, "Hallucination, auditory ": 14.608692375920151, "Hallucination, visual ": 5.512040834318139, "Hyperammonaemia ": 8.665817939994946, "Hyperprolactinaemia ": 25.00432169848642, "Hyperreflexia ": 22.62011857434509, "Hypertonia ": 6.812703460666097, "Hypothermia ": 4.774712848697141, "Hypoxia ": 3.931237559423455, "Irritability ": 2.9416183713819666, "Lethargy ": 7.957249694101176, "Leukocytosis ": 3.5071704222147417, "Mania ": 8.287095506684738, "Mental disorder ": 2.4171961297892444, "Mental impairment ": 2.661810997863701, "Mental status changes ": 4.162468380293945, "Metabolic acidosis ": 2.7703926846867457, "Mood altered ": 3.062818842060969, "Mood swings ": 3.8223233951197466, "Movement disorder ": 2.581078911780785, "Multiple drug therapy ": 41.009342614502486, "Muscle rigidity ": 21.58596416363122, "Myoclonus ": 10.635696612364184, "Neuroleptic malignant syndrome ": 17.142879721773358, "Neurotoxicity ": 4.223653893050045, "Obesity ": 5.738143285086417, "Orthostatic hypotension ": 2.4388633667419204, "Panic disorder ": 15.532924596578226, "Paranoia ": 9.838709216430772, "Parkinsonism ": 19.074003955242866, "Patient elopement ": 82.56907334482011, "Pneumonia aspiration ": 2.329287172265972, "Priapism ": 54.40247395563022, "Product use in unapproved indication ": 2.372031556906676, "Psychotic disorder ": 8.139262409338215, "Respiratory depression ": 37.90971896698693, "Restlessness ": 2.8224608212948032, "Rhabdomyolysis ": 2.862704163174849, "Salivary hypersecretion ": 30.957771260479024, "Schizophrenia ": 11.156527561526175, "Sedation ": 16.58734862341142, "Sedation complication ": 11.540622230250191, "Self-destructive behaviour ": 19.716546210210144, "Serotonin syndrome ": 8.687994599418479, "Sinus tachycardia ": 3.683198345001944, "Somnolence ": 2.3903874744104963, "Suicidal ideation ": 4.842102569902428, "Suicide attempt ": 2.150143598807894, "Tachypnoea ": 4.637826717789036, "Tardive dyskinesia ": 11.535893240526423, "Toxicity to various agents ": 7.321933732415831, "Treatment noncompliance ": 2.541804564868382, "Tremor ": 2.283729310114632, "Urinary incontinence ": 4.349393433948786, "Weight increased ": 5.454828894596825, "Wrong patient received product ": 19.8768074989713}
\ No newline at end of file
+{"Acute lymphocytic leukaemia": 15.250772378051789, "Acute myeloid leukaemia": 10.036932251202735, "Adverse drug reaction": 2.1119849409742666, "Anaemia": 2.377076731211709, "Atrial fibrillation": 2.921603661356517, "Basal cell carcinoma": 9.627657870455645, "Blood potassium decreased": 9.97575185905428, "Cardiac disorder": 2.782074947990996, "Constipation": 3.349883627511891, "Cytopenia": 4.995875148397106, "Deep vein thrombosis": 2.898067591665274, "Dehydration": 2.6484153736127154, "Diarrhoea": 2.499504202882694, "Disease progression": 2.320917921547092, "Drug hypersensitivity": 2.411516121793322, "Drug reaction with eosinophilia and systemic symptoms": 4.84042603803958, "Eosinophilia": 2.1857501146649487, "Fall": 2.1514514991222518, "Febrile neutropenia": 2.7174256942262294, "Fluid retention": 2.091768098082781, "Full blood count decreased": 38.35147417025899, "Haemoglobin decreased": 3.31988023290761, "Human chorionic gonadotropin increased": 86.14338695105104, "Hypercalcaemia": 4.229150284990906, "Immune system disorder": 4.048511256466765, "Infection": 2.26367018739353, "Laboratory test abnormal": 5.463269966696396, "Mental status changes": 2.4585997727399915, "Myelodysplastic syndrome": 18.391103665090174, "Neuropathy peripheral": 14.724573406697624, "Neutropenia": 2.3677935222050337, "Neutrophil count decreased": 5.905575450292096, "Pancytopenia": 5.882114520201873, "Plasma cell leukaemia": 107.80675680982564, "Plasma cell myeloma": 112.11239871542918, "Plasma cell myeloma recurrent": 118.21232702146835, "Plasmacytoma": 116.34919170311956, "Platelet count decreased": 6.845727276398872, "Pneumonia": 5.754258449923123, "Product dose omission issue": 2.141462934331233, "Pulmonary thrombosis": 6.988043949799658, "Rash maculo-papular": 3.874422974114067, "Red blood cell count decreased": 3.9319069787608902, "Renal disorder": 2.533634644740215, "Renal failure": 2.028086069708656, "Renal impairment": 2.721307268779273, "Sepsis": 4.783118749356878, "Septic shock": 2.861313671092111, "Skin cancer": 7.360029362946898, "Spinal compression fracture": 7.858423903424564, "Spinal fracture": 3.4699877599063083, "Squamous cell carcinoma of skin": 15.776523717308711, "Staphylococcal infection": 2.184876040133111, "Therapy non-responder": 3.001376011078795, "Thrombocytopenia": 2.4002836361789406, "Thrombosis": 5.232603298701995, "Toxic skin eruption": 2.409144866163041, "Unevaluable event": 2.469830176332058, "White blood cell count decreased": 5.198327239982825}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/947.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/947.json
index e8f2295b5bb..e40562077a0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/947.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/947.json
@@ -1 +1 @@
-{"Diarrhoea ": 11.158261065504544}
\ No newline at end of file
+{"Aplastic anaemia": 156.66864436367123, "Blood bilirubin increased": 8.652710491189472, "Disease progression": 4.600762267556851, "Haemoglobin decreased": 5.9799112277898425, "Liver disorder": 5.854211892527528, "Neutrophil count decreased": 8.744216240321132, "Platelet count decreased": 23.83967818532781, "Product use in unapproved indication": 11.813712807301815, "Renal impairment": 5.121604841723337, "Therapeutic product effect incomplete": 5.53348925887042, "Thrombocytopenia": 3.175338072471545, "White blood cell count decreased": 8.223192164994446}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/948.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/948.json
index 2c8828681a5..c7739ebae7f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/948.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/948.json
@@ -1 +1 @@
-{"Adrenal insufficiency ": 47.04643325988366, "Adrenal suppression ": 187.3555018347998, "Cortisol decreased ": 88.51905521954818, "Cushing's syndrome ": 475.6644080728068, "Cushingoid ": 123.73437360705206, "Drug interaction ": 31.49152197950092, "Drug level increased ": 12.3942102715817, "Ergot poisoning ": 787.4455344018598, "Neutropenia ": 2.162577930158074, "Osteonecrosis ": 2.06848121012976, "Osteoporosis ": 2.257155108783413, "Pancreatitis ": 3.286040564070988, "Pseudo Cushing's syndrome ": 570.5118041624851, "Secondary adrenocortical insufficiency ": 391.7042329091548, "Skin striae ": 159.8712553717871, "Weight increased ": 4.989211518431254}
\ No newline at end of file
+{"Abortion spontaneous": 5.654078537973878, "Acute kidney injury": 4.136837875356084, "Adverse event": 4.36861513039756, "Alanine aminotransferase increased": 2.3407995353814126, "Aspartate aminotransferase increased": 2.1683863683698887, "Blood alkaline phosphatase increased": 2.1974001787726, "Blood bilirubin increased": 29.99183083400323, "Blood bilirubin unconjugated increased": 91.59487959699156, "Blood creatine phosphokinase increased": 2.505911739982772, "Blood creatinine increased": 4.057703972461057, "Blood triglycerides increased": 4.994795360898335, "Caesarean section": 59.272017959283446, "Calculus urinary": 184.74203164834915, "Cholecystitis": 12.233773176654251, "Cholecystitis acute": 17.147099570275603, "Cholelithiasis": 29.8601114088961, "Cholestasis": 3.2666343409498584, "Cushing's syndrome": 14.802245477305148, "Diabetes mellitus": 2.6803133827910326, "Drug interaction": 2.584605496894881, "Drug resistance": 10.274192212131634, "Dysphagia": 2.4733034096747586, "Electrocardiogram QT prolonged": 3.1487332357555164, "Fanconi syndrome": 34.118770278916884, "Fanconi syndrome acquired": 19.91945074203826, "Foetal exposure during pregnancy": 3.1554473041098103, "Gamma-glutamyltransferase increased": 2.030095205158305, "Gastrointestinal tube insertion": 25.148317704360064, "Glomerular filtration rate decreased": 4.208226432560288, "Gynaecomastia": 9.93630983269045, "Haematuria": 2.217126970452264, "Hepatic cirrhosis": 3.768678234504326, "Hepatic cytolysis": 14.384184440457895, "Hepatic steatosis": 3.8311509001919695, "Hepatitis": 7.748112676319753, "Hepatitis C": 3.097400349434636, "Hepatitis acute": 7.743430362215176, "Hepatotoxicity": 3.263681494975544, "Hip fracture": 4.0953973062765305, "Hydronephrosis": 13.064552364159002, "Hyperbilirubinaemia": 98.03927409503956, "Jaundice": 56.45262549599393, "Lipoatrophy": 72.72424495166167, "Lipodystrophy acquired": 45.35792210685551, "Live birth": 17.04406533358518, "Liver function test abnormal": 2.58293801683463, "Maternal exposure during pregnancy": 5.0191106146855775, "Nephrolithiasis": 95.47854232241838, "Normal newborn": 47.3521230043124, "Ocular icterus": 162.10864387129527, "Osteonecrosis": 3.5002651700339324, "Pancreatitis": 5.913890930661339, "Pancreatitis acute": 3.938583819082288, "Polyneuropathy": 6.777430396939882, "Pregnancy": 31.21522719821035, "Proteinuria": 2.8791696134844176, "Renal colic": 435.5994258054364, "Renal failure": 2.8103017615482604, "Renal impairment": 2.4096596663372702, "Renal pain": 3.8921833196092233, "Renal tubular necrosis": 7.764222364023111, "Transaminases increased": 8.08946859812855, "Twin pregnancy": 127.26107473158744, "Ventricular tachycardia": 3.6456469519206514, "Viral load increased": 38.12423962785753, "Weight increased": 2.414749165524713, "Yellow skin": 9.993287100285988}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/949.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/949.json
index c31fa025db1..ce244676c3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/949.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/949.json
@@ -1 +1 @@
-{"Acute hepatic failure ": 6.380704945802501, "Acute hepatitis B ": 16.793412356686332, "Acute lung injury ": 41.44434942048056, "Acute myeloid leukaemia ": 4.829202071174824, "Acute respiratory distress syndrome ": 2.666724896224331, "Adenovirus infection ": 4.6571297170754455, "Agranulocytosis ": 5.450813582679331, "Anti-cyclic citrullinated peptide antibody positive ": 2.90581819205919, "Arthropathy ": 2.5598916915263383, "Arthropod bite ": 3.4820277293417083, "Aspergillus infection ": 4.618573352950267, "Autoimmune haemolytic anaemia ": 4.599631440746169, "B-cell lymphoma ": 7.021131089419899, "B-cell lymphoma recurrent ": 62.351405419933656, "B-lymphocyte count decreased ": 30.99748987430866, "Bacteraemia ": 5.978353536446752, "Bacterial infection ": 2.089840712621517, "Bacterial sepsis ": 5.157489484408598, "Basal cell carcinoma ": 2.7824853779707857, "Bicytopenia ": 23.16369151093126, "Blood lactate dehydrogenase increased ": 3.138886849400416, "Blood pressure diastolic abnormal ": 116.12787142112695, "Blood pressure diastolic decreased ": 24.942121355388263, "Blood pressure diastolic increased ": 32.839848477148415, "Blood pressure fluctuation ": 12.25740607277717, "Blood pressure systolic abnormal ": 148.3243939568738, "Blood pressure systolic increased ": 20.00641794514234, "Body temperature decreased ": 6.60255723606904, "Bone disorder ": 2.18311665541804, "Bone marrow failure ": 3.5784237601147124, "Bronchiectasis ": 2.3817919395280085, "Bronchopulmonary aspergillosis ": 4.476486025026864, "Bursitis ": 2.1205709233207566, "C-reactive protein increased ": 2.206613969590191, "COVID-19 pneumonia ": 8.646541050166391, "Candida infection ": 2.4289256053844577, "Cardiomyopathy ": 2.342071531028529, "Cardiotoxicity ": 2.8137131196543685, "Castleman's disease ": 26.35375761621817, "Cellulitis ": 2.4702574857767168, "Central nervous system lymphoma ": 22.012182381995828, "Cerebral aspergillosis ": 25.21120750732176, "Cerebral disorder ": 3.164397343980253, "Cervix disorder ": 23.69189430293826, "Chronic lymphocytic leukaemia ": 22.212136918986264, "Chronic lymphocytic leukaemia recurrent ": 33.993158171978635, "Chronic myeloid leukaemia ": 2.834794600584142, "Clumsiness ": 5.999418821751212, "Contraindicated product administered ": 2.045184107753752, "Cystitis haemorrhagic ": 2.4269923112699123, "Cytokine release syndrome ": 3.121974456147579, "Cytomegalovirus chorioretinitis ": 14.404498995273988, "Cytomegalovirus infection ": 4.506930796395857, "Cytomegalovirus infection reactivation ": 2.3437168626612386, "Cytomegalovirus viraemia ": 5.029090110871184, "Cytopenia ": 9.10827779289287, "Dental caries ": 2.65942640598749, "Device dislocation ": 3.755954533019195, "Diffuse large B-cell lymphoma ": 33.001508828321526, "Diffuse large B-cell lymphoma recurrent ": 65.52134446401145, "Diffuse large B-cell lymphoma refractory ": 53.69899947678527, "Diffuse large B-cell lymphoma stage IV ": 49.54207641358289, "Disease progression ": 5.858499965834046, "Disease recurrence ": 2.619232298635682, "Dislocation of vertebra ": 3.152980222828206, "Disseminated Bacillus Calmette-Guerin infection ": 77.00236255179288, "Drug effective for unapproved indication ": 2.858437953108741, "Drug hypersensitivity ": 4.54796354377316, "Drug intolerance ": 2.0212168741163885, "Duodenal ulcer perforation ": 4.016529489487501, "Ear infection ": 2.606658696923169, "Ear pruritus ": 9.56806695868124, "Ejection fraction decreased ": 2.036429819355835, "Endocarditis ": 2.1507371414184453, "Enterococcal infection ": 3.663295371341497, "Epstein-Barr virus infection ": 4.091934294376123, "Eye infection ": 4.709715159127006, "Facet joint syndrome ": 2.186981202173793, "Febrile neutropenia ": 16.070047843491135, "Fibromyalgia ": 2.2365918639676705, "Finger deformity ": 8.287996516877763, "Follicular lymphoma ": 39.17102440589634, "Folliculitis ": 2.685735105547101, "Foot fracture ": 2.3166968197252857, "Granulocyte count decreased ": 21.691994480770685, "Granulocytopenia ": 6.603366785039535, "Haematotoxicity ": 7.216792466840529, "Hand deformity ": 2.625865196199946, "Heart rate decreased ": 7.341668912577151, "Heart rate increased ": 2.1052827178991427, "Helicobacter infection ": 3.749615427759577, "Hepatitis B ": 16.74158960573574, "Hepatitis B reactivation ": 83.26249184874018, "Herpes simplex ": 2.654232040550954, "Hodgkin's disease ": 15.236068865879425, "Hordeolum ": 6.244216407819965, "Humoral immune defect ": 238.6522128619549, "Hypoalbuminaemia ": 4.177717973622568, "Hypogammaglobulinaemia ": 26.44616565656873, "Ill-defined disorder ": 4.5627170500453085, "Immune reconstitution inflammatory syndrome ": 3.4521560984508524, "Immunodeficiency ": 2.85650044819195, "Immunoglobulins decreased ": 13.363436198413766, "Immunosuppression ": 5.795676848269999, "Impaired healing ": 3.051832204922506, "Infection ": 3.559668631478021, "Infusion related reaction ": 9.151837978951018, "Intentional product use issue ": 3.1498801228938698, "Interstitial lung disease ": 5.822639004511467, "Intestinal perforation ": 4.144391115874987, "JC virus infection ": 18.671698031993053, "Joint swelling ": 2.604745402270192, "Klebsiella bacteraemia ": 16.87453514401889, "Klebsiella infection ": 5.662584519829539, "Klebsiella sepsis ": 14.637567154789684, "Leukopenia ": 3.784945212991589, "Ligament sprain ": 6.044906870906838, "Lip disorder ": 17.210922557143547, "Localised infection ": 4.079913037962451, "Low birth weight baby ": 2.10237602363072, "Lung opacity ": 2.0082885858915183, "Lymphocyte count decreased ": 6.777745947608089, "Lymphocytosis ": 4.593567857445642, "Lymphoma ": 4.67503546461384, "Lymphopenia ": 5.878505093663969, "Lymphoproliferative disorder ": 6.171210265561445, "Mantle cell lymphoma ": 29.88309948155111, "Mantle cell lymphoma recurrent ": 27.407653036525947, "Marginal zone lymphoma recurrent ": 323.8160277764217, "Maternal exposure timing unspecified ": 2.9237512487509574, "Metastasis ": 2.3220098721552054, "Mucosal inflammation ": 2.704544466110942, "Muscle injury ": 2.309407024990068, "Myasthenia gravis ": 2.3522965180062028, "Myelodysplastic syndrome ": 7.532113316446473, "Myelodysplastic syndrome with single lineage dysplasia ": 21.14767341963071, "Myelosuppression ": 17.771099440325496, "Nasopharyngitis ": 2.7828605520688083, "Neutropenia ": 6.417052210893263, "Neutropenic infection ": 17.668595973878624, "Neutropenic sepsis ": 22.872962403719743, "Neutrophil count decreased ": 12.74424517965492, "Neutrophil count increased ": 2.9620141285114108, "Nodule ": 3.532314893811435, "Non-Hodgkin's lymphoma ": 5.880504835299436, "Non-Hodgkin's lymphoma recurrent ": 60.31046632054312, "Noninfective encephalitis ": 21.410416223711024, "Oedema ": 2.6931213804520997, "Oesophageal candidiasis ": 4.129937549063519, "Off label use ": 2.1871226582578545, "Onychomycosis ": 4.016773770975223, "Oxygen saturation decreased ": 5.994611888015808, "Pancytopenia ": 4.400352041460621, "Pharyngeal ulceration ": 12.82537123462368, "Platelet count decreased ": 2.387845084975321, "Platelet disorder ": 5.046152382377004, "Pneumocystis jirovecii pneumonia ": 33.200442139688704, "Pneumonia ": 3.35969180175371, "Pneumonia bacterial ": 3.740429481927064, "Pneumonia cytomegaloviral ": 6.441163796596672, "Pneumonia fungal ": 4.613207032307488, "Pneumonia viral ": 4.361100585922058, "Polymyositis ": 8.943281330508277, "Poor venous access ": 15.933221914564468, "Post transplant lymphoproliferative disorder ": 6.6189281996480895, "Posterior reversible encephalopathy syndrome ": 3.472420200296689, "Procedural haemorrhage ": 4.991470222230597, "Product use in unapproved indication ": 2.283857454161457, "Productive cough ": 2.3197037309607724, "Progressive multifocal leukoencephalopathy ": 19.67093241726139, "Pseudomonas infection ": 3.249586449277101, "Pulmonary toxicity ": 10.935116694941216, "Recurrent cancer ": 10.24114600103334, "Remission not achieved ": 133.02310288664484, "Respiratory tract infection ": 2.8710002115688544, "Rheumatoid arthritis ": 2.361410234758249, "Rheumatoid factor positive ": 2.055448615396435, "Richter's syndrome ": 50.98188402297676, "Second primary malignancy ": 7.716291209636893, "Sepsis ": 3.1868621999115248, "Septic shock ": 3.886442055664939, "Sinusitis ": 2.604384826438487, "Skin laceration ": 2.005542838379549, "Small intestinal obstruction ": 2.8814229693865765, "Squamous cell carcinoma ": 2.21085086764347, "Staphylococcal bacteraemia ": 4.137839760243665, "Staphylococcal sepsis ": 4.76105818679071, "Synovitis ": 2.6140392681667413, "Therapy non-responder ": 2.4078835683234185, "Therapy partial responder ": 9.660154056827263, "Throat irritation ": 2.592024034163344, "Thrombocytopenia ": 2.621037791284936, "Tooth abscess ": 2.464687561731058, "Tooth disorder ": 2.513779430353284, "Tooth infection ": 5.137408110558667, "Traumatic lung injury ": 6.143339557167915, "Tumour lysis syndrome ": 20.2613060708329, "Upper limb fracture ": 2.6420945475793345, "Varicella zoster virus infection ": 4.057886656531585, "Viral upper respiratory tract infection ": 8.74165906153246, "Wheezing ": 2.3492137366699177, "White blood cell count decreased ": 9.566078493125795, "Wound infection ": 2.018068702556373}
\ No newline at end of file
+{"Diarrhoea": 2.5036433699764395, "Drug interaction": 6.067452934974008}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/95.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/95.json
index bcdbda1e528..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/95.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/95.json
@@ -1 +1 @@
-{"Completed suicide ": 93.52661870911469}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/950.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/950.json
index 577913e92ab..704d1c87ced 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/950.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/950.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.245188769291827, "Angina pectoris ": 4.64321205926022, "Aphasia ": 2.8177158397889865, "Atrial fibrillation ": 3.5577553749959256, "Blood creatine phosphokinase increased ": 2.569324450883228, "Blood urea increased ": 8.15278520847671, "Bradycardia ": 3.019722875778368, "Brain natriuretic peptide increased ": 33.519517355124016, "Cardiac failure ": 3.618114900962575, "Cardiac failure congestive ": 2.6077167924750766, "Cardiac murmur ": 12.048183436293035, "Cardio-respiratory arrest ": 2.7018355195017514, "Cerebral haemorrhage ": 2.6629144268565463, "Chronic obstructive pulmonary disease ": 3.839103435986262, "Circulatory collapse ": 3.322376805809953, "Completed suicide ": 13.677973024852404, "Deep vein thrombosis ": 4.7615426551943605, "Delirium ": 4.953983993032037, "Disorientation ": 2.700465605601525, "Drug interaction ": 10.239689970945657, "Drug-induced liver injury ": 2.306312553190929, "Dyspnoea exertional ": 3.12858777321857, "Epistaxis ": 3.593364127299268, "Gastrointestinal haemorrhage ": 6.93947588683711, "Glycosylated haemoglobin increased ": 5.690617275314498, "Haematemesis ": 3.800712710131725, "Haematuria ": 4.782536841380658, "Haemoptysis ": 6.144725613183323, "Haemorrhage ": 3.931876757998063, "Hemiparesis ": 6.69434751972392, "Intentional overdose ": 7.056958957338947, "International normalised ratio increased ": 4.366425158860022, "Labelled drug-drug interaction medication error ": 11.36288257218647, "Melaena ": 7.669519975721385, "Myoglobin blood increased ": 44.567448222234816, "Nasal congestion ": 3.8404634944945606, "Oedema peripheral ": 4.082292613670128, "Oxygen saturation decreased ": 2.84112514037655, "Productive cough ": 3.8019640934753776, "Pulmonary embolism ": 4.852968068291953, "Rales ": 15.35023473892008, "Red cell distribution width increased ": 32.451923574487544, "Rhabdomyolysis ": 2.330031726648471, "Suicide attempt ": 2.211895002782046, "Suspected suicide ": 82.23291132768826, "Tachypnoea ": 5.382116393626405, "Thrombosis ": 5.392012464658995, "Toxicity to various agents ": 8.797043638871614, "Troponin increased ": 10.404494787869009, "Upper gastrointestinal haemorrhage ": 8.643328108856178, "Vitreous haemorrhage ": 35.231536595786174}
\ No newline at end of file
+{"Affective disorder": 2.300511666048243, "Anaemia": 13.720636164537844, "Anal pruritus": 9.494457793957295, "Anorectal discomfort": 6.377334237445123, "Anorectal disorder": 9.232428133105154, "Aplasia pure red cell": 27.072688433532356, "Ascites": 8.615231177692301, "Autoimmune haemolytic anaemia": 3.329684294857318, "Autoimmune hepatitis": 4.282821429664738, "Blood bilirubin increased": 5.363175651413097, "Bone marrow failure": 2.937554684951757, "Chronic hepatitis C": 21.21490797082938, "Cryoglobulinaemia": 40.89345089828407, "Cutaneous sarcoidosis": 49.87616868919748, "Depression": 2.288724542443676, "Depressive symptom": 4.092827579778238, "Dermatitis": 3.115985392289459, "Drug ineffective": 13.12304036212615, "Drug reaction with eosinophilia and systemic symptoms": 2.9904915604709, "Encephalopathy": 3.523350458763207, "Gastric varices": 38.79697485049733, "Genotype drug resistance test positive": 69.62172040059913, "Granulocytopenia": 2.226176488481406, "Graves' disease": 7.182308576945927, "Haemoglobin abnormal": 5.890354563154924, "Haemoglobin decreased": 7.043508002422353, "Haemolysis": 15.752057155528544, "Haemolytic anaemia": 16.574781536664425, "Hepatic cancer": 7.509593228685498, "Hepatic cirrhosis": 18.211423949475275, "Hepatic encephalopathy": 15.927670214224351, "Hepatic failure": 7.293326038199944, "Hepatic fibrosis": 8.477722510818781, "Hepatic lesion": 5.493003906844376, "Hepatitis B reactivation": 14.056526656310446, "Hepatitis C": 298.6586198673844, "Hepatitis C RNA increased": 90.82319023474894, "Hepatitis C RNA positive": 204.29920361086772, "Hepatitis C virus test positive": 208.4716387124404, "Hepatitis E": 23.013618978041563, "Hepatocellular carcinoma": 21.61363963307781, "Hyperbilirubinaemia": 9.310040241056877, "Hypocalcaemia": 7.493382316681053, "Hypomagnesaemia": 12.208683398658328, "Immune system disorder": 2.439683977107897, "Immune thrombocytopenia": 2.3115701136270284, "Jaundice": 3.4760911986690397, "Leukopenia": 3.0720354220031885, "Liver transplant": 23.68568270437797, "Liver transplant rejection": 12.654757578857504, "Lymphopenia": 3.032454403605515, "Mania": 2.823502289625839, "Mental status changes": 2.2090090052939235, "Mitochondrial toxicity": 11.496602397107832, "Oesophageal varices haemorrhage": 26.03871474924258, "Pancytopenia": 2.9024323561220244, "Paranoia": 2.147162603587857, "Pathogen resistance": 3.805979651383172, "Personality change": 2.737295244151301, "Polydipsia": 3.9943487712233257, "Polyuria": 2.3949521372821843, "Porphyria non-acute": 28.203000947941906, "Portal hypertension": 8.161965845362309, "Portal vein thrombosis": 11.541880933481238, "Proctalgia": 4.497240026359802, "Product use issue": 2.106283945635109, "Psychotic disorder": 3.5022921063778685, "Pulmonary arterial hypertension": 2.3689584657338605, "Red blood cell count decreased": 2.548765900302668, "Remission not achieved": 59.43979644407972, "Renal impairment": 2.952741410901281, "Retinopathy": 9.647398177445456, "Sarcoidosis": 35.234136354622734, "Skin fissures": 3.4608382545625664, "Skin laceration": 3.022576464560005, "Spontaneous bacterial peritonitis": 21.08094225289485, "Therapy cessation": 3.754166716740325, "Therapy non-responder": 4.367578418801494, "Transfusion": 6.069081172467718, "Treatment failure": 30.163825690657102, "Treatment noncompliance": 3.250176080624052, "Type 1 diabetes mellitus": 3.659968100447061, "Unevaluable event": 3.18860014779985, "Varices oesophageal": 13.629255882454062, "Viral load increased": 13.45464430674092, "Viral mutation identified": 28.356824525381988, "Virologic failure": 62.376829354287736}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/951.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/951.json
index a5847f52a78..36994f76b52 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/951.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/951.json
@@ -1 +1 @@
-{"Confusional state ": 4.14339828602836, "Fall ": 13.921532541929569, "Hyponatraemia ": 16.34681190706136, "Inappropriate antidiuretic hormone secretion ": 127.0636169739774, "Mental status changes ": 45.407689271142, "Somnolence ": 5.116450159824217, "Wrist fracture ": 133.4719166609001}
\ No newline at end of file
+{"Alanine aminotransferase increased": 8.865599627801314, "Anaemia": 2.652907608378116, "Aspartate aminotransferase increased": 9.142394708369558, "Blood alkaline phosphatase increased": 4.309969433314161, "Blood bilirubin increased": 4.362074356800702, "Blood creatinine increased": 2.0874397691908726, "Bone lesion": 106.27735925697556, "Bone pain": 2.2162236238182427, "Breast cancer": 11.848224408275744, "Breast cancer metastatic": 106.076078243657, "Breast cancer recurrent": 24.06288820845183, "Breast mass": 36.2931240431416, "Carbohydrate antigen 15-3 increased": 358.6665543722972, "Carcinoembryonic antigen increased": 39.950177391668255, "Disease progression": 3.5577342865313857, "Electrocardiogram QT prolonged": 19.127989752419097, "Febrile neutropenia": 2.6518169682372834, "Gamma-glutamyltransferase increased": 3.1493419256252144, "Granulocytopenia": 6.447586491781753, "Haematocrit decreased": 4.957351605025616, "Haematotoxicity": 19.478325362592496, "Haemoglobin decreased": 3.207140828356476, "Hepatic enzyme increased": 2.888928198072392, "Hepatic failure": 3.4202275596948484, "Hepatic lesion": 24.1811488612435, "Hepatic steatosis": 3.3403508294835342, "Hepatitis": 2.631150189797532, "Hepatotoxicity": 42.37642320431733, "Hormone receptor positive HER2 negative breast cancer": 739.6284857264747, "Hot flush": 2.758221051930096, "Hypertransaminasaemia": 14.751527832335034, "Leukopenia": 15.256245389582494, "Liver function test increased": 3.722892574065247, "Liver injury": 2.180673050781036, "Malignant neoplasm progression": 17.327820122738164, "Metastases to bone": 77.19685287946722, "Metastases to central nervous system": 6.822928870819823, "Metastases to liver": 44.954693367645305, "Metastases to lung": 36.50779916579864, "Metastases to lymph nodes": 40.90150870083818, "Metastases to pleura": 69.54439858823935, "Metastases to spine": 37.56694829658316, "Metastasis": 18.504186471736244, "Neutropenia": 38.78272531943481, "Neutrophil count decreased": 6.38435292781037, "PIK3CA-activated mutation": 139.72286085065116, "Pleural effusion": 4.335817570943956, "Pneumonitis": 4.221716719579039, "Pulmonary mass": 5.1817882879946335, "Skin toxicity": 10.68621909425426, "Therapeutic response decreased": 2.8099632725825394, "Therapy partial responder": 45.722913034238296, "Thrombocytopenia": 2.5568568031768706, "Transaminases increased": 5.981890159573674, "Tumour marker increased": 18.321001091922437, "Vitiligo": 31.45282931179806, "White blood cell count decreased": 5.349684788091665}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/952.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/952.json
index 2d56d4bf14f..bb3200eae82 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/952.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/952.json
@@ -1 +1 @@
-{"Agranulocytosis ": 10.16501930291214, "Anaphylactic reaction ": 2.9448325292803945, "Bronchospasm ": 7.977436285500203, "COVID-19 pneumonia ": 9.656751711134955, "Chest discomfort ": 2.315525257279948, "Cytokine release syndrome ": 5.886648882569596, "Dysphagia ": 3.24763391179389, "Dysphonia ": 3.551249212173429, "Dyspnoea ": 2.813128663126992, "Erythema ": 4.307301799748449, "Feeling hot ": 2.8585958553710897, "Flushing ": 5.677521770463573, "Hepatic cytolysis ": 9.220755875308834, "Hypersensitivity ": 2.846424826582385, "Hypotension ": 2.944731517168264, "Infusion related reaction ": 32.75428987528744, "Interstitial lung disease ": 2.103770410507968, "Laryngeal oedema ": 17.021341113537023, "Nasal congestion ": 4.475975245137927, "Neutropenia ": 3.7522762089759674, "Oropharyngeal discomfort ": 14.92179927166421, "Oxygen saturation decreased ": 10.308229891350392, "Pancytopenia ": 3.110215357561937, "Product use in unapproved indication ": 2.057349258444716, "Pruritus ": 4.361945542553429, "Rash ": 2.0491216448762763, "Rash maculo-papular ": 2.174883727483841, "Serum sickness ": 108.53942842560888, "Throat irritation ": 25.85324246592377, "Throat tightness ": 15.643042117437563, "Thrombocytopenia ": 2.3127552684957293, "Tumour lysis syndrome ": 15.228527141675633, "Urticaria ": 5.034284140491563}
\ No newline at end of file
+{"Adverse reaction": 52.27602465770154, "Agranulocytosis": 7.717355657915041, "Amyotrophic lateral sclerosis": 287.1360725659436, "Angioedema": 2.397005643615922, "C-reactive protein increased": 5.569495621042735, "Condition aggravated": 2.529703687805848, "Death": 4.225347330789885, "Disease progression": 19.985820636324505, "Dysphagia": 10.107918984872065, "Gastric fistula": 847.6445785237527, "Hepatic enzyme increased": 2.8071925575445054, "Interstitial lung disease": 10.14147402809956, "Motor neurone disease": 1354.1392518161315, "Oxygen saturation decreased": 4.895303902439751, "Pancreatitis": 6.768214897223107, "Pancreatitis acute": 12.25409631709886, "Renal impairment": 2.1193589760876006, "Respiratory failure": 3.777063594567253, "Speech disorder": 8.068271285287935}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/953.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/953.json
index 532fa010440..52f16fe9c90 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/953.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/953.json
@@ -1 +1 @@
-{"Abdominal abscess ": 9.802551288980698, "Abscess ": 12.76697828917951, "Abscess limb ": 16.375334716636576, "Acute respiratory failure ": 2.140948477912535, "Adenocarcinoma of colon ": 13.215535321994038, "Administration site erythema ": 4.555353574159624, "Administration site reaction ": 9.76559080280046, "Alanine aminotransferase increased ": 2.8387161044951994, "Alveolitis ": 6.007747942811758, "Anaphylactic reaction ": 2.1948980630238366, "Anaphylactoid reaction ": 2.5075888989323065, "Aneurysm ": 3.2738460299816365, "Aortic aneurysm ": 2.4132038316319524, "Aortic dissection ": 12.181739776967426, "Aphthous ulcer ": 6.506769765352767, "Appendicitis ": 3.035884836961405, "Arthritis ": 4.570244922257798, "Arthritis bacterial ": 52.76979609328048, "Arthritis infective ": 12.060393585170235, "Aspergillus infection ": 3.691255643890668, "Bacteraemia ": 2.070889258345577, "Bacterial sepsis ": 4.0289742310772665, "Basal cell carcinoma ": 6.237390607335793, "Blood bilirubin unconjugated increased ": 8.625370382212012, "Blood cholesterol increased ": 4.1322498031401205, "Blood fibrinogen decreased ": 28.473692933584942, "Blood triglycerides increased ": 3.868470873712615, "Breast cancer ": 2.355476740324448, "Bronchitis ": 2.9870738475352554, "Bursitis infective ": 45.55672976524258, "C-reactive protein decreased ": 20.935020794155918, "Cardiovascular insufficiency ": 9.13666196492407, "Cellulitis ": 6.728418253679414, "Cholecystitis ": 2.1185356113089937, "Cholecystitis acute ": 2.73903000671301, "Colectomy ": 4.268171263404194, "Complement factor C3 decreased ": 51.210197692023165, "Complement factor C4 decreased ": 68.89234096867287, "Conjunctivitis ": 2.706036538087259, "Cutaneous vasculitis ": 5.666156588459383, "Cyst ": 2.2720829103468296, "Cystitis ": 2.3483100403950345, "Demyelination ": 3.916072392354402, "Dermo-hypodermitis ": 46.81089203782034, "Device difficult to use ": 4.176812386467438, "Device related infection ": 8.41545010273417, "Diverticular perforation ": 123.6517494308418, "Diverticulitis ": 25.154669912635143, "Diverticulum ": 4.385108878102787, "Diverticulum intestinal ": 3.3951013805874832, "Drug delivery system malfunction ": 4.033659416823783, "Empyema ": 12.175701292448736, "Encephalitis ": 2.1181556979425618, "Encephalitis herpes ": 10.242279309257995, "Endocarditis ": 7.115966452420175, "Eosinophil count increased ": 2.203292143590022, "Eosinophilia ": 2.520556594026388, "Epiglottitis ": 18.876635679650526, "Erysipelas ": 20.866742332041056, "Escherichia urinary tract infection ": 4.211150812452773, "Exposure via skin contact ": 13.95104498284655, "Extremity necrosis ": 18.15925739244891, "Fournier's gangrene ": 2.513871438874748, "Furuncle ": 2.4909499354376625, "Gamma-glutamyltransferase increased ": 2.729119837730104, "Gangrene ": 2.341501140583239, "Gastric perforation ": 6.683887345713415, "Gastrointestinal inflammation ": 4.279092082189036, "Gastrointestinal perforation ": 8.988673882237274, "Giant cell arteritis ": 15.954836955133548, "Gingivitis ": 3.111351241874685, "Granuloma annulare ": 10.954148654951895, "Haemophagocytic lymphohistiocytosis ": 5.819406856156153, "Haemorrhagic diathesis ": 2.237922972050047, "Hepatic cytolysis ": 5.702460799916748, "Hepatitis ": 2.1674650179273898, "Hepatitis E ": 10.954148654951895, "Hepatocellular injury ": 3.94479832497383, "Herpes virus infection ": 3.0791500327288777, "Herpes zoster ": 2.9809067398324367, "High density lipoprotein increased ": 25.15007310612645, "Humerus fracture ": 4.200922381218249, "Hypercholesterolaemia ": 12.080394971391984, "Hypersensitivity ": 2.3153696596273066, "Hypertensive crisis ": 3.481496542311326, "Hypertransaminasaemia ": 3.7582705693042735, "Hypertriglyceridaemia ": 2.6715366198221475, "Hypofibrinogenaemia ": 84.09788450445117, "Ill-defined disorder ": 3.585409656612296, "Immunosuppression ": 3.630010803493457, "Impaired healing ": 2.662961609394065, "Infection ": 4.613048949273127, "Infectious pleural effusion ": 15.447790079377029, "Infusion related reaction ": 3.8298921110424806, "Injection site erythema ": 2.258374685064464, "Injection site haemorrhage ": 2.9192062701370878, "Injection site hypersensitivity ": 11.38466984580444, "Injection site oedema ": 4.684748817671361, "Injection site pruritus ": 2.566014453918702, "Injection site rash ": 8.080737646875523, "Injection site reaction ": 4.807364579615544, "Injection site urticaria ": 5.934573817635965, "Injury associated with device ": 6.305817697059696, "Intentional product use issue ": 10.91746812994703, "Intercepted product storage error ": 91.2333790269778, "Interleukin level increased ": 38.13758660722405, "Intermittent claudication ": 5.844934264630948, "International normalised ratio decreased ": 2.2931311523347, "Intervertebral discitis ": 23.955481382886827, "Intestinal haemorrhage ": 2.2840997311813798, "Intestinal ischaemia ": 3.0777713132913496, "Intestinal perforation ": 13.508199682716992, "Invasive ductal breast carcinoma ": 3.566458064282616, "Iritis ": 3.913541186695612, "Joint effusion ": 2.02321047590045, "Juvenile idiopathic arthritis ": 13.54834243078919, "Keratitis ": 4.899352643818668, "Large intestine perforation ": 23.01936606358383, "Leukopenia ": 7.27509717547501, "Lipids increased ": 14.949862124036123, "Liver abscess ": 8.002409543469943, "Liver function test increased ": 5.080413656551617, "Localised infection ": 4.935662320416527, "Loss of therapeutic response ": 24.85376139922004, "Low density lipoprotein increased ": 11.425854238321786, "Lower respiratory tract infection ": 2.680866474465975, "Lung abscess ": 9.55864542874819, "Lung adenocarcinoma ": 9.563765550138871, "Lung disorder ": 2.068675500840253, "Lung neoplasm ": 8.881654310470072, "Lung neoplasm malignant ": 2.0629536082075366, "Lymphocytosis ": 4.453725117219718, "Lymphopenia ": 3.877571606952749, "Malignant melanoma ": 6.834719714660357, "Melanocytic naevus ": 4.603834993479543, "Meningitis ": 2.9906611078709435, "Mouth ulceration ": 4.2709706922509145, "Multiple organ dysfunction syndrome ": 3.063738967462874, "Necrosis ": 2.748543957606701, "Necrotising fasciitis ": 17.436429214243372, "Needle issue ": 7.48149772967829, "Neoplasm ": 5.300055248234694, "Neuromyelitis optica spectrum disorder ": 10.641241399405978, "Neutropenia ": 6.794016578416188, "Neutrophil count decreased ": 2.70358225377982, "Neutrophilia ": 4.068980182953355, "No adverse event ": 12.437043016325376, "Off label use ": 3.1688841216931056, "Oral herpes ": 3.2173590882702285, "Oral mucosal blistering ": 2.638078872489457, "Organising pneumonia ": 3.0779881733699046, "Osteitis ": 12.130229887250422, "Osteomyelitis ": 6.09917260942971, "Otitis media ": 2.2840760977104293, "Ovarian cancer ": 2.2502118498866626, "Pancreatitis acute ": 2.470161641379549, "Panniculitis ": 5.677589710435543, "Paronychia ": 4.034797646177136, "Peripheral ischaemia ": 7.70196228660544, "Peritonitis ": 18.31268717934086, "Phlebitis ": 2.5851814088665805, "Pneumocystis jirovecii pneumonia ": 4.3530857004683705, "Pneumonia ": 2.5641633827535704, "Pneumonia pneumococcal ": 13.891886005784276, "Poor quality product administered ": 2.235481285835389, "Postoperative wound infection ": 3.532339241485574, "Product storage error ": 4.377676497346008, "Psoriasis ": 2.2858492251678544, "Pulmonary fibrosis ": 2.313871643786244, "Pulmonary tuberculosis ": 6.057486210905966, "Pulpitis dental ": 25.1759905446634, "Pustule ": 4.755863440826454, "Pyelonephritis ": 3.860160517408251, "Pyoderma gangrenosum ": 11.48707020822632, "Renal abscess ": 14.47549316241664, "Renal function test abnormal ": 2.591779240194443, "Respiratory tract infection ": 3.2540977379548406, "Rheumatoid arthritis ": 3.88898519919823, "Rheumatoid nodule ": 15.546423284824536, "Sepsis ": 5.334309455541207, "Septic shock ": 6.597440388542451, "Skin infection ": 8.288503732025632, "Skin necrosis ": 2.64555770468652, "Skin reaction ": 4.599662227632093, "Skin ulcer ": 6.271592681443155, "Small intestinal perforation ": 7.818934608564471, "Soft tissue infection ": 18.621910898572697, "Squamous cell carcinoma ": 2.429158696009776, "Staphylococcal sepsis ": 11.305697959882789, "Streptococcal sepsis ": 21.4324120417734, "Stress fracture ": 5.089898321611462, "Subcutaneous abscess ": 8.389742910958251, "Sudden hearing loss ": 2.092543426129972, "Syringe issue ": 11.570149793157396, "Tenosynovitis ": 3.61970430627072, "Thrombocytopenia ": 2.743558919967543, "Thyroid cancer ": 2.86594340249732, "Tonsillitis ": 2.988708181254945, "Tooth abscess ": 4.368585701232323, "Tooth disorder ": 2.76200650249902, "Transaminases increased ": 5.401867152349441, "Tuberculosis ": 5.4307525926416895, "Ulcerative keratitis ": 7.244791505876638, "Upper respiratory tract infection ": 3.0111873986057134, "Urinary tract infection ": 3.202303577403311, "Urosepsis ": 3.1017044890155963, "Urticaria ": 2.1563565363282, "Vasculitis ": 4.062132377885773, "Wound infection ": 4.691349370859911}
\ No newline at end of file
+{"Condition aggravated": 2.104734489129125, "Death": 17.58785499525715, "Disease progression": 10.671788302266242, "Drug interaction": 2.727567420568221, "Gastrointestinal disorder": 4.771775034783161, "Interstitial lung disease": 11.600384773928296, "Pancreatitis acute": 15.922121402782386}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/954.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/954.json
index 9d3cd08f778..c1ed407a503 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/954.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/954.json
@@ -1 +1 @@
-{"Acute myocardial infarction ": 10.607729548212124, "Arteriosclerosis ": 25.98107655929585, "Atrial fibrillation ": 5.488415766008535, "Cardiac arrest ": 4.991640345160891, "Cardiac disorder ": 13.679936150459982, "Cardiac failure ": 7.93055405535386, "Cardiac failure congestive ": 79.51624517906069, "Cardiac operation ": 52.14395134093398, "Cardio-respiratory arrest ": 13.002599755829332, "Cardiomyopathy ": 18.6057005735506, "Cardiovascular disorder ": 15.261591344174978, "Cerebrovascular accident ": 22.750281720428145, "Coronary artery bypass ": 47.88629246673455, "Coronary artery disease ": 51.15801394968886, "Death ": 2.628977326013082, "Diabetes mellitus inadequate control ": 8.764515565412617, "Fluid retention ": 9.649490985024938, "Hypertension ": 2.3806036168080547, "Myocardial infarction ": 45.30991079890095, "Myocardial ischaemia ": 23.74918556953053, "Oedema ": 4.548903594873108, "Transient ischaemic attack ": 10.861642518248212, "Weight increased ": 4.6438363895354575}
\ No newline at end of file
+{"Abnormal weight gain": 5.844719752000349, "Abortion induced": 2.406804424088067, "Abscess": 2.215172342875747, "Acne": 48.28799154725069, "Adenocarcinoma of colon": 8.502584586204156, "Adverse drug reaction": 4.115643075660525, "Alanine aminotransferase increased": 2.251497959767095, "Alopecia areata": 3.2816221960115097, "Ankle fracture": 2.010785037473997, "Ankylosing spondylitis": 2.740502188036837, "Aphthous ulcer": 4.654877464059297, "Arthritis": 3.239781860498574, "Arthritis bacterial": 3.579710145998364, "Autoimmune disorder": 2.5378324857900827, "Basal cell carcinoma": 3.4267096136339203, "Blood cholesterol increased": 5.692191286036434, "Blood creatine phosphokinase increased": 9.2273138553766, "Blood iron decreased": 3.851378730247112, "Blood triglycerides increased": 6.08280357680665, "Breast cancer female": 11.434171600555716, "C-reactive protein increased": 3.2193377715557885, "Cellulitis": 2.666736030245744, "Cerebrovascular accident": 2.45725881116352, "Clostridium difficile infection": 2.594368059909305, "Colectomy": 16.86010954523838, "Colitis ulcerative": 6.825088940554495, "Colon cancer": 2.7669168560099977, "Coronavirus infection": 10.590958273888855, "Crohn's disease": 3.420913320434586, "Cutaneous T-cell lymphoma": 19.79352519504253, "Cytomegalovirus colitis": 7.816991524822693, "Cytomegalovirus infection": 2.261166496199863, "Deep vein thrombosis": 4.615440868449578, "Dermatitis acneiform": 12.647724315834663, "Dermatitis atopic": 74.41847015510488, "Diverticulitis": 5.060329565299181, "Diverticulitis intestinal perforated": 93.13321749475104, "Diverticulum": 2.524780953005868, "Diverticulum intestinal haemorrhagic": 6.284673034019529, "Eczema": 3.224190553330547, "Eczema herpeticum": 251.4088891281736, "Embolism": 5.12286971818122, "Embolism venous": 14.991067074716028, "Erysipelas": 4.251572581841722, "Erythema nodosum": 3.2443334935014256, "Faecal calprotectin increased": 22.822491508261507, "Folliculitis": 4.532756837440648, "Foot deformity": 2.102469250205938, "Foot operation": 5.343728108083647, "Frequent bowel movements": 3.602311933750688, "Frustration tolerance decreased": 2.5417027037971858, "Furuncle": 4.965253144851592, "Gastrointestinal perforation": 24.585505658215705, "General symptom": 10.9416287543033, "Genital herpes": 18.492770235745017, "Genital herpes zoster": 68.77505227064998, "Gingival pain": 6.64556612979422, "Haematocrit decreased": 2.086892732968893, "Hepatitis B": 3.7427343481723234, "Hepatitis E": 20.153480267784808, "Herpes ophthalmic": 35.041685281600294, "Herpes simplex": 16.660184351716676, "Herpes virus infection": 20.772925021600937, "Herpes zoster": 10.132960571407825, "Herpes zoster disseminated": 15.070652717335111, "High density lipoprotein increased": 23.29461949501023, "Hordeolum": 11.088576857376932, "Hypercholesterolaemia": 5.589889432036182, "Ileostomy": 44.419145394754246, "Immunodeficiency": 4.402767954120173, "Immunosuppression": 8.373648942701143, "Impetigo": 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4.76851561153506, "Lymphocyte count decreased": 2.313012442958937, "Lymphocyte count increased": 4.935641035164708, "Lymphoma": 5.703873718687124, "Lymphopenia": 3.700926823491523, "Malabsorption": 5.823319031513019, "Malignant melanoma": 3.76671441919269, "Meningitis": 3.781622176954624, "Middle insomnia": 3.485751518855452, "Mobility decreased": 2.0806755927729164, "Mouth ulceration": 2.026595379879625, "Musculoskeletal disorder": 4.637191805398272, "Neoplasm malignant": 2.173143974391931, "Nerve compression": 3.6887652585268, "Neuroendocrine carcinoma of the skin": 27.121008505975063, "Ophthalmic herpes zoster": 9.633438659922293, "Oral candidiasis": 2.5117021592241957, "Oral herpes": 10.63158919847345, "Organising pneumonia": 2.358659241082788, "Osteoarthritis": 2.76009506262012, "Ostomy bag placement": 429.4756896737913, "Overweight": 3.582355717443691, "Pain of skin": 2.300886528262314, "Papilloma viral infection": 6.657472651351819, "Papule": 2.0210288182134826, "Phlebitis": 3.910286132817981, "Platelet count increased": 4.767040776168548, "Pneumocystis jirovecii pneumonia": 9.259363737595075, "Pneumonia bacterial": 3.8008173629931736, "Polyarthritis": 3.603096765145468, "Portal vein thrombosis": 4.479269291615943, "Post herpetic neuralgia": 3.4027934212015105, "Post procedural complication": 2.8859516441939697, "Post procedural infection": 5.760553634569338, "Product residue present": 49.28854878727334, "Psoriasis": 3.446990237333143, "Psoriatic arthropathy": 3.124552412675261, "Pulmonary embolism": 7.0693411740730046, "Pulmonary thrombosis": 3.466796007833671, "Purulent discharge": 6.189888923183759, "Pustule": 8.319022454219752, "Rash pustular": 5.490306524150304, "Red blood cell sedimentation rate increased": 2.379149599534041, "Respiratory tract infection": 4.802190196783728, "Retinal artery occlusion": 3.2205726395740206, "Retinal detachment": 2.342646398939883, "Retinal vein occlusion": 5.782430950692493, "Rheumatic disorder": 5.935076745649219, "Rheumatoid arthritis": 7.010658667884783, "Rosacea": 28.782105964682536, "Semen discolouration": 281.32331418923536, "Skin cancer": 3.834460634460203, "Skin disorder": 4.0992513176823175, "Skin lesion": 3.114191853322711, "Skin plaque": 4.581448387236343, "Sluggishness": 2.0297640777563317, "Spinal compression fracture": 2.3385270942241543, "Spinal fracture": 2.633322352995437, "Spinal operation": 5.263853503819379, "Spinal pain": 2.051991419835044, "Spinal stenosis": 2.828774897854293, "Squamous cell carcinoma": 2.8734146081110303, "Squamous cell carcinoma of skin": 6.107475566061689, "Subcutaneous abscess": 4.1075232480520745, "Superficial vein thrombosis": 2.419650249940031, "Superinfection": 10.964382100420629, "Surgery": 3.245233338287654, "Suspected COVID-19": 2.4478201425573203, "Synovitis": 4.205473027920404, "Therapeutic product effect decreased": 4.595543285937847, "Therapeutic product effect incomplete": 4.322893890497591, "Therapeutic response shortened": 4.075667005363176, "Thrombosis": 3.3502237626978366, "Tongue neoplasm malignant stage unspecified": 13.650786008308922, "Tonsillitis": 3.535301996118612, "Tooth abscess": 2.8278876827907213, "Transaminases increased": 3.2627674513934024, "Tuberculosis": 4.8639678234905, "Ulcer": 5.210048446739557, "Unevaluable event": 6.49664671793017, "Upper respiratory tract infection": 2.81947510517638, "Varicella zoster virus infection": 9.662735858293374, "Venous thrombosis": 2.984455620275952, "Venous thrombosis limb": 7.449497138615168, "Vitamin D decreased": 4.008090052715969, "Vulvovaginal mycotic infection": 3.135168175014865, "Weight increased": 5.6708430708250175}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/955.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/955.json
index 787262c6173..a4cee37d86b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/955.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/955.json
@@ -1 +1 @@
-{"Agitation ": 4.612722887600406, "Altered state of consciousness ": 8.57877698802745, "Crying ": 49.99577614566888, "Cyanosis ": 38.8852798724276, "Diarrhoea ": 3.822300686128263, "Febrile convulsion ": 94.908314252122, "Haematochezia ": 30.082022344830197, "Hypotonia ": 49.32683900561248, "Hypotonic-hyporesponsive episode ": 158.4509413574325, "Injection site erythema ": 4.666092149636292, "Injection site oedema ": 67.93583811313353, "Injection site warmth ": 5.178936562105896, "Intussusception ": 110.65632499809968, "Lethargy ": 5.092917150057466, "Pallor ": 31.68844573933464, "Rotavirus infection ": 278.5709048829182, "Seizure ": 4.156488645428448, "Somnolence ": 2.363075003142224, "Unresponsive to stimuli ": 19.37607921844701, "Vomiting ": 3.4204404361414475}
\ No newline at end of file
+{"Bradycardia": 17.292315872430073, "Condition aggravated": 9.511550497386043, "Dyspnoea exertional": 40.80273422367407, "Hypotension": 8.088631519447818, "Left-to-right cardiac shunt": 20394.860412082395, "Pulmonary hypertension": 102.00807033669888, "Therapeutic product effect incomplete": 20.75869366568164, "Vascular resistance pulmonary decreased": 79946.97217693867}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/956.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/956.json
index 2f1b37b05d2..8323b2ae2f7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/956.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/956.json
@@ -1 +1 @@
-{"Autism spectrum disorder ": 218.14145827741063, "Dehydration ": 10.289193891678735, "Diarrhoea ": 2.6816781958229385, "Gastroenteritis ": 134.8481763047518, "Intestinal obstruction ": 551.3179136022165, "Intussusception ": 607.3828774637363, "Language disorder ": 167.08595571253818, "Metal poisoning ": 1116.1260303304462, "Neurological symptom ": 123.43464368199488, "Pyrexia ": 2.348532485624861, "Vomiting ": 2.4963923697950223}
\ No newline at end of file
+{"Crohn's disease": 54.517793726689206, "Drug ineffective": 2.06705673289151, "Off label use": 12.405851195697602, "Psoriasis": 64.94692932419719, "Psoriatic arthropathy": 24.8556723405198}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/957.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/957.json
index 0855169c0e8..017ee06452b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/957.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/957.json
@@ -1 +1 @@
-{"Abdominal distension ": 3.046152572389491, "Abdominal mass ": 39.91776686321335, "Abdominal pain ": 4.171482174602547, "Abdominal rigidity ": 9.674878005715062, "Abdominal tenderness ": 8.782813809642887, "Abnormal faeces ": 19.91638527895577, "Accidental underdose ": 48.418433487119, "Acidosis ": 3.917466984994348, "Anal fissure ": 13.289277331478871, "Apathy ": 4.533970063022273, "Apnoea ": 14.852593495546712, "Appendicectomy ": 42.45810536472584, "Appendix disorder ": 24.6155580379301, "Asphyxia ": 3.839890286940167, "Barium enema ": 2708.880104596388, "Breath sounds abnormal ": 3.617247116940925, "Bronchiolitis ": 11.8543894487794, "Bronchitis ": 2.0554792476108785, "Chapped lips ": 8.18730910684673, "Choking ": 5.406119733405012, "Colitis ": 2.589563341612862, "Combined immunodeficiency ": 291.2914584332081, "Constipation ": 2.070468506815821, "Crying ": 42.33107167521289, "Cyanosis ": 5.36311115761145, "Cytomegalovirus infection ": 2.1144566738048844, "Dairy intolerance ": 105.22214826210984, "Decreased activity ": 3.141866625260112, "Dehydration ": 8.225102492971235, "Dermatitis atopic ": 7.809937662654876, "Dermatitis diaper ": 51.23444185689549, "Developmental delay ": 2.680326354591637, "Diarrhoea ": 6.856920330073041, "Diarrhoea haemorrhagic ": 29.65236647421152, "Diet refusal ": 82.95499891934783, "Ear infection ": 3.7530443921108825, "Enema administration ": 3157.629152286781, "Enteritis ": 17.220739490262165, "Enterocolitis ": 3.9780205953263583, "Expired product administered ": 2.38477974434178, "Eye movement disorder ": 3.0815105586530165, "Faeces discoloured ": 23.57647510891971, "Faeces pale ": 11.023061783310832, "Faeces soft ": 9.737524210947472, "Failure to thrive ": 12.46705238011334, "Febrile convulsion ": 4.864111002089184, "Flatulence ": 6.612665176735744, "Fluid intake reduced ": 21.33518026677384, "Fontanelle bulging ": 66.65174812380684, "Food allergy ": 3.811296640628752, "Frequent bowel movements ": 4.446760420273724, "Gastroenteritis ": 44.20771096311233, "Gastroenteritis rotavirus ": 3799.2644022541904, "Gastroenteritis viral ": 5.232300856243053, "Gastrointestinal necrosis ": 14.624890838600027, "Gastrointestinal sounds abnormal ": 18.05493430872045, "Growth retardation ": 5.562266355780661, "Haematemesis ": 2.192814698861416, "Haematochezia ": 73.02097858188027, "Haemophagocytic lymphohistiocytosis ": 2.430479498462464, "Hypophagia ": 15.891236686506671, "Hypotonia ": 8.508433263001, "Hypotonic-hyporesponsive episode ": 34.30344988437864, "Hypovolaemia ": 3.5095967220087267, "Ileus ": 3.563286202626382, "Immune thrombocytopenia ": 8.410311648318114, "Inappropriate schedule of product administration ": 3.1752599169597207, "Incomplete course of vaccination ": 15.284630442685868, "Infantile colic ": 140.07736793415765, "Infantile spasms ": 20.20028806648838, "Infantile spitting up ": 769.410623990887, "Infantile vomiting ": 104.53136654764334, "Intensive care ": 20.622532025437835, "Intestinal anastomosis ": 100.94140798348938, "Intestinal obstruction ": 3.372379828043359, "Intestinal perforation ": 2.3091471269116965, "Intestinal resection ": 28.288548034055815, "Intussusception ": 2624.760502157841, "Irritability ": 14.852874171118836, "Irritability postvaccinal ": 2.4578526523356543, "Kawasaki's disease ": 258.4659671772212, "Lactose intolerance ": 12.131904994862603, "Laparotomy ": 149.57965230494827, "Lethargy ": 5.142984259217696, "Listless ": 4.227785841512978, "Meningitis ": 3.6612257708683407, "Metabolic acidosis ": 2.374378329602276, "Milk allergy ": 216.33844959140868, "Mucous stools ": 198.6830155109137, "Myocardial injury ": 11.973287805411006, "Occult blood positive ": 14.636764576177596, "Otitis media ": 8.663267440188225, "Pallor ": 10.1835103315336, "Petechiae ": 2.2613576401587507, "Pharyngeal erythema ": 13.229747586236387, "Poor feeding infant ": 18.78964523807031, "Poor quality sleep ": 2.753218166522784, "Product administered to patient of inappropriate age ": 21.06347028043164, "Rectal haemorrhage ": 2.403234445151947, "Regurgitation ": 47.10181395724627, "Respiratory syncytial virus infection ": 5.095594102355359, "Restlessness ": 6.300689708218667, "Retching ": 2.35156960741533, "Rhinitis ": 3.664601465994487, "Rotavirus infection ": 1864.961970002797, "Rotavirus test positive ": 10751.495924523562, "Salmonellosis ": 21.529745053860704, "Screaming ": 30.956921983246534, "Secondary transmission ": 137.78317015243871, "Selective eating disorder ": 16.760705427012635, "Small intestinal obstruction ": 3.438239630486306, "Sudden infant death syndrome ": 45.34884902881807, "Surgery ": 9.262282280071972, "Tearfulness ": 4.29196254850502, "Thrombocytopenic purpura ": 34.92222192097596, "Tooth malformation ": 704.8909425198522, "Transfusion ": 2.1698440744487995, "Underdose ": 5.201048088896739, "Unresponsive to stimuli ": 3.656149158110854, "Upper respiratory tract infection ": 6.1183450931921, "Urine output decreased ": 9.802830415513, "Vaccination error ": 23.7675830682938, "Vaccination failure ": 4.128893392982556, "Viral infection ": 3.917497209711664, "Vomiting ": 5.79298788801477, "Vomiting projectile ": 40.69756006526693, "Weight gain poor ": 50.16241960286814}
\ No newline at end of file
+{"Abnormal behaviour": 7.068079384800062, "Acute psychosis": 17.990680499979902, "Adverse drug reaction": 3.012132011989039, "Aggression": 4.053013405625042, "Agitation": 5.633948181427527, "Akathisia": 5.32539636822857, "Alanine aminotransferase increased": 2.106335512013991, "Aspartate aminotransferase increased": 2.868585812657826, "Asphyxia": 7.301962654714328, "Ataxia": 5.013150284737163, "Blood creatine phosphokinase increased": 3.7414610368613226, "Blood prolactin increased": 22.948509763138265, "Bradykinesia": 16.140439068982165, "Brain injury": 6.020931689875798, "Catatonia": 22.139566954908773, "Circulatory collapse": 2.420592657576212, "Cognitive disorder": 2.2310978319221086, "Confusional state": 3.192707645869039, "Cyanosis": 3.040235704421174, "Delirium": 3.1082039489478555, "Dementia": 2.26469208410736, "Depressed level of consciousness": 14.849125585452851, "Drug interaction": 8.208174958199752, "Drug level increased": 2.6775494459026072, "Dysarthria": 4.998529316077903, "Dyskinesia": 3.3110846549008937, "Dystonia": 11.700979329501202, "Emotional disorder": 6.337126418785396, "Encephalopathy": 4.175079612766444, "Extrapyramidal disorder": 35.78011921299647, "Feeling abnormal": 3.492201982016653, "Galactorrhoea": 10.581923308275991, "Generalised tonic-clonic seizure": 2.0941628084335417, "Gynaecomastia": 14.851192660703886, "Hallucination, auditory": 14.608692375920151, "Hallucination, visual": 5.512040834318139, "Hyperammonaemia": 8.665817939994946, "Hyperprolactinaemia": 25.00432169848642, "Hyperreflexia": 22.62011857434509, "Hypertonia": 6.812703460666097, "Hypothermia": 4.774712848697141, "Hypoxia": 3.931237559423455, "Irritability": 2.9414778197824805, "Lethargy": 7.957249694101176, "Leukocytosis": 3.5071704222147417, "Mania": 8.287095506684738, "Mental disorder": 2.4171961297892444, "Mental impairment": 2.661810997863701, "Mental status changes": 4.162468380293945, "Metabolic acidosis": 2.7703926846867457, "Mood altered": 3.062818842060969, "Mood swings": 3.8223233951197466, "Movement disorder": 2.581078911780785, "Multiple drug therapy": 41.009342614502486, "Muscle rigidity": 21.58596416363122, "Myoclonus": 10.635696612364184, "Neuroleptic malignant syndrome": 17.142879721773358, "Neurotoxicity": 4.223653893050045, "Obesity": 5.738143285086417, "Orthostatic hypotension": 2.43833833783586, "Panic disorder": 15.532924596578226, "Paranoia": 9.838709216430772, "Parkinsonism": 19.074003955242866, "Patient elopement": 82.56907334482011, "Pneumonia aspiration": 2.329287172265972, "Priapism": 54.40247395563022, "Product use in unapproved indication": 2.3719575425829658, "Psychotic disorder": 8.139262409338215, "Respiratory depression": 37.90971896698693, "Restlessness": 2.822311877252325, "Rhabdomyolysis": 2.862704163174849, "Salivary hypersecretion": 30.94256950895232, "Schizophrenia": 11.156527561526175, "Sedation": 16.58734862341142, "Sedation complication": 11.540622230250191, "Self-destructive behaviour": 19.716546210210144, "Serotonin syndrome": 8.687994599418479, "Sinus tachycardia": 3.683198345001944, "Somnolence": 2.3903611084461844, "Suicidal ideation": 4.842102569902428, "Suicide attempt": 2.150143598807894, "Tachypnoea": 4.637166709491953, "Tardive dyskinesia": 11.535893240526423, "Toxicity to various agents": 7.321933732415831, "Treatment noncompliance": 2.541804564868382, "Tremor": 2.2836429972135472, "Urinary incontinence": 4.349393433948786, "Weight increased": 5.454828894596825, "Wrong patient received product": 19.8768074989713}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/958.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/958.json
index d914d0be8fa..3a38a5f6c11 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/958.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/958.json
@@ -1 +1 @@
-{"Drug withdrawal syndrome ": 51.14117313413747, "Impulse-control disorder ": 1163.3644995102547}
\ No newline at end of file
+{"Diarrhoea": 11.158167952193777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/959.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/959.json
index 71faa8cb41e..2fe546d0ab7 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/959.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/959.json
@@ -1 +1 @@
-{"Accidental underdose ": 15.58824161343866, "Acute myeloid leukaemia ": 2.0236207879988832, "Adverse drug reaction ": 2.6676802329273364, "Adverse event ": 27.40599369339656, "Alanine aminotransferase increased ": 5.712813801765201, "Anaemia ": 6.530667060772686, "Ascites ": 4.4295438950554695, "Aspartate aminotransferase increased ": 4.882063655985347, "Asthenia ": 2.229463512257189, "Blood alkaline phosphatase increased ": 2.566268309356594, "Blood creatinine increased ": 7.525438598676626, "Blood magnesium decreased ": 33.12169306081485, "Blood potassium decreased ": 5.754090876297713, "Blood sodium decreased ": 2.591703245579112, "Blood test abnormal ": 8.182961645812316, "Carbohydrate antigen 125 increased ": 822.8072402865545, "Constipation ": 5.132886110970955, "Cytopenia ": 2.256026468290968, "Death ": 3.946058961384429, "Decreased appetite ": 3.0903596724900027, "Dehydration ": 5.043125168538401, "Drug intolerance ": 2.3966967651935382, "Dysgeusia ": 8.58117751879402, "Full blood count abnormal ": 11.69700743732657, "Glomerular filtration rate decreased ": 4.193727772477089, "Haematocrit decreased ": 5.8683464905226925, "Haematotoxicity ": 4.10209729463261, "Haemoglobin decreased ": 8.746314146323266, "Hernia ": 6.633738957093603, "Hypersomnia ": 2.5809900352431043, "Hypertransaminasaemia ": 5.010802015573565, "Hypophagia ": 11.623187792810995, "Illness ": 2.1399406483950565, "Intentional underdose ": 12.42558380467375, "Intestinal obstruction ": 15.398804757094736, "Laboratory test abnormal ": 14.57198169930636, "Liver function test abnormal ": 3.320690882441154, "Liver function test increased ": 6.4920965469468825, "Malignant neoplasm progression ": 18.765646195545816, "Malnutrition ": 4.121488334961979, "Metastases to central nervous system ": 9.00918446382834, "Myelodysplastic syndrome ": 8.928459387780606, "Nausea ": 2.2120777799631868, "Neoplasm ": 5.61590484322116, "Neuropathy peripheral ": 4.5785570826168085, "Neutropenia ": 2.186498153780497, "Ovarian cancer ": 6.22399101680361, "Ovarian cancer metastatic ": 61.51599018863623, "Ovarian cancer recurrent ": 719.381654576542, "Photosensitivity reaction ": 6.377257826963176, "Platelet count decreased ": 8.9070094950562, "Pleural effusion ": 2.036136003862858, "Prescribed underdose ": 16.198406409227303, "Product dose omission issue ": 8.629674163290986, "Product use in unapproved indication ": 2.113586973061879, "Recurrent cancer ": 42.9710601906414, "Red blood cell count decreased ": 18.509743577598037, "Renal function test abnormal ": 28.269337352129163, "Renal impairment ": 2.620265014411065, "Small intestinal obstruction ": 27.70613270006536, "Sunburn ": 13.300510090289832, "Surgery ": 4.27672475825635, "Taste disorder ": 5.807960413659807, "Therapy partial responder ": 15.494220586701829, "Thrombocytopenia ": 4.231605740596249, "Transaminases increased ": 2.0770075614156966, "Transfusion ": 9.138928960232992, "Tumour marker increased ": 27.72934008417512, "Underdose ": 11.124479474940012, "Urinary tract infection ": 2.239860888398015, "Vomiting ": 2.1140566544432366, "White blood cell count decreased ": 4.619791886356677}
\ No newline at end of file
+{"Adrenal insufficiency": 47.04643325988366, "Adrenal suppression": 187.3555018347998, "Cortisol decreased": 88.51905521954818, "Cushing's syndrome": 475.6644080728068, "Cushingoid": 123.73437360705206, "Drug interaction": 31.49152197950092, "Drug level increased": 12.3942102715817, "Ergot poisoning": 787.4455344018598, "Neutropenia": 2.162484939969594, "Osteonecrosis": 2.06848121012976, "Osteoporosis": 2.257155108783413, "Pancreatitis": 3.286040564070988, "Pseudo Cushing's syndrome": 570.5118041624851, "Secondary adrenocortical insufficiency": 391.7042329091548, "Skin striae": 159.8712553717871, "Weight increased": 4.989211518431254}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/96.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/96.json
index 25a4f530d9f..f0893b26a95 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/96.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/96.json
@@ -1 +1 @@
-{"Blister ": 50.60769786611604, "Conjunctivitis ": 236.7319672946979, "Genital erosion ": 7210.221152950711, "Lip erosion ": 2995.653479617848, "Nikolsky's sign ": 3068.614566788939, "Oral mucosa erosion ": 1806.993202921764, "Pruritus ": 9.156194915220588, "Pyrexia ": 2.48377731868219, "Rash papular ": 167.12587408025297, "Toxic epidermal necrolysis ": 162.71917378687976}
\ No newline at end of file
+{"Acute kidney injury": 62.45208257491737}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/960.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/960.json
index 9e26dfeeb6e..88d639b9ea8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/960.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/960.json
@@ -1 +1 @@
-{}
\ No newline at end of file
+{"Acute hepatic failure": 6.375628584151174, "Acute hepatitis B": 16.780053313370097, "Acute lung injury": 41.41137940320655, "Acute myeloid leukaemia": 4.825360060366488, "Acute respiratory distress syndrome": 2.66460338998514, "Adenovirus infection": 4.653424953707644, "Agranulocytosis": 5.446476363809668, "Anti-cyclic citrullinated peptide antibody positive": 2.9035063545025985, "Arthropathy": 2.557854891706039, "Arthropod bite": 3.479257796286234, "Aspergillus infection": 4.614899114539711, "Autoimmune haemolytic anaemia": 4.595972321829091, "B-cell lymphoma": 7.015545716166528, "B-cell lymphoma recurrent": 62.3018031835912, "B-lymphocyte count decreased": 30.972831522835538, "Bacteraemia": 5.973597400071235, "Bacterial infection": 2.088178183339054, "Bacterial sepsis": 5.153386683297725, "Basal cell carcinoma": 2.7802718298538784, "Bicytopenia": 23.145263239513, "Blood lactate dehydrogenase increased": 3.1363896029386646, "Blood pressure diastolic abnormal": 116.0354773775987, "Blood pressure diastolic decreased": 24.92227720653555, "Blood pressure diastolic increased": 32.81372107648853, "Blood pressure fluctuation": 12.247653025128942, "Blood pressure systolic abnormal": 148.20638169563844, "Blood pressure systolic increased": 19.99049856084969, "Body temperature decreased": 6.597304423277463, "Bone disorder": 2.181379912924627, "Bone marrow failure": 3.575576968240346, "Bronchiectasis": 2.3798972014282387, "Bronchopulmonary aspergillosis": 4.472924831469649, "Bursitis": 2.1188839004796804, "C-reactive protein increased": 2.2048583433110505, "COVID-19 pneumonia": 8.63966181408633, "Candida infection": 2.426993288996871, "Cardiomyopathy": 2.340208310825517, "Cardiotoxicity": 2.811474792144245, "Castleman's disease": 26.33279332047389, "Cellulitis": 2.468292148659837, "Central nervous system lymphoma": 21.994671352109517, "Cerebral aspergillosis": 25.19115202430057, "Cerebral disorder": 3.161880019241564, "Cervix disorder": 23.67304750201344, "Chronic lymphocytic leukaemia": 22.175278819675206, "Chronic lymphocytic leukaemia recurrent": 33.96611630345069, "Chronic myeloid leukaemia": 2.8325395193778893, "Clumsiness": 5.994646281394334, "Contraindicated product administered": 2.043556897101198, "Cystitis haemorrhagic": 2.4250616369948124, "Cytokine release syndrome": 3.11949070750866, "Cytomegalovirus chorioretinitis": 14.393039693302445, "Cytomegalovirus infection": 4.5033452050036775, "Cytomegalovirus infection reactivation": 2.341852426990054, "Cytomegalovirus viraemia": 5.025089383707743, "Cytopenia": 9.093695647179546, "Dental caries": 2.657310799911742, "Device dislocation": 3.752966680516759, "Diffuse large B-cell lymphoma": 32.97525118432485, "Diffuse large B-cell lymphoma recurrent": 65.46921452981843, "Diffuse large B-cell lymphoma refractory": 53.65627949750675, "Diffuse large B-cell lymphoma stage IV": 49.50266585958754, "Disease progression": 5.853837598887114, "Disease recurrence": 2.6171485163007087, "Dislocation of vertebra": 3.150472034718183, "Disseminated Bacillus Calmette-Guerin infection": 76.94110551115148, "Drug effective for unapproved indication": 2.856164072581936, "Drug hypersensitivity": 4.544344353285957, "Drug intolerance": 2.0196086596621554, "Duodenal ulcer perforation": 4.013334017329695, "Ear infection": 2.6045850017667767, "Ear pruritus": 9.56045511525553, "Ejection fraction decreased": 2.034809775509157, "Endocarditis": 2.149026242120611, "Enterococcal infection": 3.6603812409776806, "Epstein-Barr virus infection": 4.088679090293736, "Eye infection": 4.705968500043808, "Facet joint syndrome": 2.185241450283601, "Febrile neutropenia": 16.057256808715636, "Fibromyalgia": 2.234812505911918, "Finger deformity": 8.281403143467042, "Follicular lymphoma": 39.13986195316407, "Folliculitis": 2.683598424238676, "Foot fracture": 2.314853786206414, "Granulocyte count decreased": 21.67473625431221, "Granulocytopenia": 6.596194452730753, "Haematotoxicity": 7.211051079679289, "Hand deformity": 2.623776071645356, "Heart rate decreased": 7.335827436130102, "Heart rate increased": 2.1036075820644147, "Helicobacter infection": 3.7466323239213386, "Hepatitis B": 16.72827038006642, "Hepatitis B reactivation": 83.19623849410237, "Herpes simplex": 2.6521205666547587, "Hodgkin's disease": 15.223947930808542, "Hordeolum": 6.239249150590987, "Humoral immune defect": 238.4623629674742, "Hypoalbuminaemia": 4.174394487375136, "Hypogammaglobulinaemia": 26.42512546433008, "Ill-defined disorder": 4.559086718709007, "Immune reconstitution inflammatory syndrome": 3.449409778609375, "Immunodeficiency": 2.8542280005071445, "Immunoglobulins decreased": 13.352805673393895, "Immunosuppression": 5.791066233533313, "Impaired healing": 3.04940419178873, "Infection": 3.556836059049377, "Infusion related reaction": 9.144554945194564, "Intentional product use issue": 3.147373916101883, "Interstitial lung disease": 5.818005275093872, "Intestinal perforation": 4.14109410597642, "JC virus infection": 18.656844498237287, "Joint swelling": 2.602672788659851, "Klebsiella bacteraemia": 16.86111151313305, "Klebsiella infection": 5.658079866612463, "Klebsiella sepsis": 14.625922889196596, "Leukopenia": 3.78145409418028, "Ligament sprain": 6.040097973690509, "Lip disorder": 17.197230871656547, "Localised infection": 4.076667251662476, "Low birth weight baby": 2.100703536647327, "Lung opacity": 2.0066910035925734, "Lymphocyte count decreased": 6.772353738862478, "Lymphocytosis": 4.589913685975032, "Lymphoma": 4.671316202631428, "Lymphopenia": 5.873828237726312, "Lymphoproliferative disorder": 6.16630108447986, "Mantle cell lymphoma": 29.859327270456756, "Mantle cell lymphoma recurrent": 27.38585046319454, "Marginal zone lymphoma recurrent": 323.5584399177592, "Maternal exposure timing unspecified": 2.921425411671803, "Metastasis": 2.3201627114694903, "Mucosal inflammation": 2.7023927870343023, "Muscle injury": 2.307569824353733, "Myasthenia gravis": 2.3504252437874524, "Myelodysplastic syndrome": 7.526120802220703, "Myelodysplastic syndrome with single lineage dysplasia": 21.13085046508849, "Myelosuppression": 17.75695152098869, "Nasopharyngitis": 2.780433477649772, "Neutropenia": 6.411665997326174, "Neutropenic infection": 17.65454072939461, "Neutropenic sepsis": 22.854764685889563, "Neutrophil count decreased": 12.734102017267622, "Neutrophil count increased": 2.959657810308834, "Nodule": 3.529504776717144, "Non-Hodgkin's lymphoma": 5.875826724523357, "Non-Hodgkin's lymphoma recurrent": 60.26248834922296, "Noninfective encephalitis": 21.393384073508525, "Oedema": 2.6909785753567204, "Oesophageal candidiasis": 4.126652145243305, "Off label use": 2.1852954610650204, "Onychomycosis": 4.013578437512434, "Oxygen saturation decreased": 6.024550090277188, "Pancytopenia": 4.396850597107402, "Pharyngeal ulceration": 12.81516869417161, "Platelet count decreased": 2.385945033508182, "Platelet disorder": 5.042138197852018, "Pneumocystis jirovecii pneumonia": 33.174023641582735, "Pneumonia": 3.3570177725794297, "Pneumonia bacterial": 3.737453870178405, "Pneumonia cytomegaloviral": 6.436039848177806, "Pneumonia fungal": 4.6095371833263545, "Pneumonia viral": 4.357631341478373, "Polymyositis": 8.936166895953438, "Poor venous access": 15.920546704437507, "Post transplant lymphoproliferative disorder": 6.613662652376533, "Posterior reversible encephalopathy syndrome": 3.469657766791467, "Procedural haemorrhage": 4.98749950496952, "Product use in unapproved indication": 2.2819686598133435, "Productive cough": 2.3178581930874107, "Progressive multifocal leukoencephalopathy": 19.655282681471512, "Pseudomonas infection": 3.247001363894992, "Pulmonary toxicity": 10.926416862664292, "Recurrent cancer": 10.232998949904122, "Remission not achieved": 132.9172752129024, "Respiratory tract infection": 2.9592777501163483, "Rheumatoid arthritis": 2.359531260077865, "Rheumatoid factor positive": 2.053813475488952, "Richter's syndrome": 50.94132659808098, "Second primary malignancy": 7.7101523300463395, "Sepsis": 3.1843264002876235, "Septic shock": 3.883349921069093, "Sinusitis": 2.6023127258758327, "Skin laceration": 2.003947404509688, "Small intestinal obstruction": 2.879130778259264, "Squamous cell carcinoma": 2.209092120937684, "Staphylococcal bacteraemia": 4.134548093693012, "Staphylococcal sepsis": 4.757270683474585, "Synovitis": 2.611959621425908, "Therapy non-responder": 2.405757020561908, "Therapy partial responder": 9.65246853899483, "Throat irritation": 2.589961826478061, "Thrombocytopenia": 2.6187046596161103, "Tooth abscess": 2.462726908606096, "Tooth disorder": 2.51177965121084, "Tooth infection": 5.1333211657057385, "Traumatic lung injury": 6.138452567303527, "Tumour lysis syndrome": 20.245185427883733, "Upper limb fracture": 2.639992690347173, "Varicella zoster virus infection": 4.054658631217095, "Viral upper respiratory tract infection": 8.734705070048902, "Wheezing": 2.347250931143213, "White blood cell count decreased": 9.558464074404473, "Wound infection": 2.016463340231286}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/961.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/961.json
index 1f09aca7018..9928b4b6571 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/961.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/961.json
@@ -1 +1 @@
-{"Caesarean section ": 15.033093308490317, "Central venous catheterisation ": 167.16862441343702, "Complication of pregnancy ": 124.7474474094501, "Condition aggravated ": 4.563913703395952, "Device related infection ": 30.379321726271023, "Drug ineffective ": 3.3693267227332027, "Drug ineffective for unapproved indication ": 26.010284677450294, "Hereditary angioedema ": 384.81613983022, "Hysterectomy ": 22.422541020961425, "Illness ": 2.6508149923534488, "Incorrect route of product administration ": 6.665687103122151, "Infection ": 2.3199258258702296, "Insurance issue ": 52.37275706918357, "Intentional product use issue ": 67.23278723665948, "Kidney infection ": 16.055461176545894, "Laryngeal oedema ": 17.31579009665415, "Maternal exposure during breast feeding ": 16.68983578534393, "Maternal exposure during pregnancy ": 8.816119739164813, "Nephrolithiasis ": 8.54046866738051, "Pharyngeal swelling ": 134.7075176265005, "Pneumonia ": 2.99532969122357, "Poor venous access ": 92.5799569758312, "Product dose omission issue ": 6.0486406563471045, "Product use in unapproved indication ": 9.749662277291426, "Respiratory tract infection ": 4.417830492592935, "Respiratory tract oedema ": 268.59597081081745, "Road traffic accident ": 3.083005395505062, "Sepsis ": 5.507044753008927, "Sinusitis ": 6.101029614380689, "Staphylococcal infection ": 4.8779349148566284, "Stress ": 5.023775538339215, "Surgery ": 4.581646733683935, "Therapeutic product effect incomplete ": 12.941331693397478, "Throat tightness ": 3.8643172316644057, "Thrombosis ": 6.541343816846738, "Tooth infection ": 14.606423592705545, "Underdose ": 20.15351565744619, "Upper respiratory tract infection ": 4.706274534941705, "Vascular access complication ": 874.2489271379047, "Vascular access site complication ": 13158.557593359932, "Vascular access site infection ": 4122.597864893069, "Vascular device infection ": 48.001159839670464, "Vein rupture ": 80.15516947555281, "Weight fluctuation ": 41.670516432440685}
\ No newline at end of file
+{"Acute kidney injury": 2.104876878792548, "Angina pectoris": 4.506459331394318, "Aphasia": 2.897060795711641, "Atrial fibrillation": 3.3734224320930823, "Blood creatine phosphokinase increased": 2.333335416632721, "Blood urea increased": 7.403863647950863, "Bradycardia": 2.7422023684968435, "Brain natriuretic peptide increased": 30.440916811142237, "Cardiac failure": 3.285369065284477, "Cardiac failure congestive": 2.3679905264133208, "Cardiac murmur": 10.941615364880697, "Cardio-respiratory arrest": 2.718038399664715, "Cerebral haemorrhage": 2.8593007264503445, "Chronic obstructive pulmonary disease": 3.486451176929566, "Circulatory collapse": 3.017243762437892, "Completed suicide": 12.419771711266495, "Deep vein thrombosis": 4.323992491451202, "Delirium": 4.4988662113327855, "Disorientation": 2.7166602035279754, "Drug interaction": 9.297260131329889, "Drug-induced liver injury": 2.094369008106905, "Dyspnoea exertional": 2.841231163759238, "Epistaxis": 3.2631607818272244, "Gastrointestinal haemorrhage": 6.301591078463458, "Glycosylated haemoglobin increased": 5.167941820910829, "Haematemesis": 3.451328955769747, "Haematuria": 4.343169736802652, "Haemoptysis": 5.580265929700638, "Haemorrhage": 3.5705666449232965, "Hemiparesis": 7.28423278734293, "Intentional overdose": 6.408274978644332, "International normalised ratio increased": 3.965285818107559, "Labelled drug-drug interaction medication error": 10.318956831505435, "Melaena": 6.963917729964493, "Myoglobin blood increased": 40.47431124147492, "Nasal congestion": 3.487709706411384, "Neuralgia": 2.235073271433804, "Oedema peripheral": 3.707035108207879, "Oxygen saturation decreased": 2.83420373383857, "Productive cough": 3.4527465462444105, "Pulmonary embolism": 4.534481140498195, "Rales": 13.940389525255403, "Red cell distribution width increased": 29.471489672709158, "Rhabdomyolysis": 2.11602140541644, "Suicide attempt": 2.0087083680942315, "Suspected suicide": 74.6747860796015, "Tachypnoea": 4.887118206946417, "Thrombosis": 5.257176858496522, "Toxicity to various agents": 7.987782435999422, "Troponin increased": 10.700892487360433, "Upper gastrointestinal haemorrhage": 7.84723748288804, "Vitreous haemorrhage": 31.995819740308228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/962.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/962.json
index ebe19088e60..693276407cf 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/962.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/962.json
@@ -1 +1 @@
-{"Drug ineffective ": 6.815424653327351, "Off label use ": 7.967177607368685, "Product use issue ": 25.461701209919077, "Seizure ": 15.031197376624112, "Therapy non-responder ": 34.21516320776984, "Treatment failure ": 110.27445421657272}
\ No newline at end of file
+{"Confusional state": 4.14339828602836, "Fall": 13.92117564065068, "Hyponatraemia": 16.34681190706136, "Inappropriate antidiuretic hormone secretion": 127.0636169739774, "Mental status changes": 45.407689271142, "Somnolence": 5.116393763879284, "Wrist fracture": 133.4719166609001}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/963.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/963.json
index 6ef4fec2e27..22b49570f87 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/963.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/963.json
@@ -1 +1 @@
-{"Off label use ": 6.394765689587745}
\ No newline at end of file
+{"Agranulocytosis": 10.16501930291214, "Anaphylactic reaction": 2.944769938415741, "Bronchospasm": 7.977436285500203, "COVID-19 pneumonia": 9.656751711134955, "Chest discomfort": 2.3154439805777387, "Cytokine release syndrome": 5.886648882569596, "Dysphagia": 3.24763391179389, "Dysphonia": 3.551249212173429, "Dyspnoea": 2.813086858405845, "Erythema": 4.3072596527709965, "Feeling hot": 2.8585958553710897, "Flushing": 5.677521770463573, "Hepatic cytolysis": 9.220755875308834, "Hypersensitivity": 2.846424826582385, "Hypotension": 2.944663424902707, "Infusion related reaction": 32.75428987528744, "Interstitial lung disease": 2.103770410507968, "Laryngeal oedema": 17.021341113537023, "Nasal congestion": 4.475975245137927, "Neutropenia": 3.7521148056414, "Oropharyngeal discomfort": 14.92179927166421, "Oxygen saturation decreased": 10.307677812330326, "Pancytopenia": 3.110215357561937, "Product use in unapproved indication": 2.0572850954277078, "Pruritus": 4.361892684346148, "Rash": 2.049093492732556, "Rash maculo-papular": 2.174883727483841, "Serum sickness": 108.53942842560888, "Throat irritation": 25.85324246592377, "Throat tightness": 15.643042117437563, "Thrombocytopenia": 2.312537680477477, "Tumour lysis syndrome": 15.228527141675633, "Urticaria": 5.034232536230056}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/964.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/964.json
index 554264a785d..51f67e23e3b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/964.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/964.json
@@ -1 +1 @@
-{"Acute graft versus host disease ": 10.048406242167546, "Acute myeloid leukaemia ": 16.14233706205119, "Anaemia ": 10.02495019478464, "BK virus infection ": 23.62533352555422, "Basal cell carcinoma ": 15.14115750571396, "Basophil count increased ": 93.88774821125796, "Blood lactate dehydrogenase increased ": 5.94750162090218, "Bronchopulmonary aspergillosis ": 12.569243110210758, "Chronic graft versus host disease ": 29.79428541269381, "Concomitant disease aggravated ": 10.24179554525715, "Cytomegalovirus infection ": 15.936931540109356, "Cytomegalovirus infection reactivation ": 27.362096545156287, "Cytopenia ": 25.42609783087823, "Disease recurrence ": 4.717073933498607, "Epstein-Barr virus infection reactivation ": 36.77429039852652, "Graft versus host disease ": 7.164081477653011, "Haematocrit decreased ": 11.088714795018666, "Haematoma ": 2.144443065236377, "Haemoglobin abnormal ": 20.69857129316561, "Haemoglobin decreased ": 12.130477059089282, "Herpes simplex ": 9.455190357220689, "Leukocytosis ": 21.679110582355044, "Leukopenia ": 2.324104356528106, "Lymphocyte count increased ": 24.70879291504317, "Lymphopenia ": 4.17910572908198, "Malignant neoplasm progression ": 3.025916556907649, "Melaena ": 2.128013885062618, "Monocyte count increased ": 22.491540704952385, "Myelofibrosis ": 150.31914257748258, "Neutrophil count increased ": 23.806962190466784, "Neutrophilia ": 26.978614278571342, "Night sweats ": 2.9029705271776423, "Pancytopenia ": 3.4887651396967585, "Platelet count abnormal ": 41.54108764443495, "Platelet count decreased ": 10.175209854682803, "Platelet count increased ": 25.26832647194433, "Pleural effusion ": 2.365438966547613, "Pneumonia ": 2.2340735925975173, "Primary myelofibrosis ": 453.3999335105938, "Product use in unapproved indication ": 14.251164013965353, "Product use issue ": 2.079218485591212, "Pulmonary tuberculosis ": 14.872243484455126, "Red blood cell count decreased ": 6.181037183481511, "Red cell distribution width increased ": 18.3639300344472, "Respiratory failure ": 2.5129418885779797, "Second primary malignancy ": 125.6648281816963, "Sepsis ": 3.5740135215158437, "Septic shock ": 4.020458857667626, "Skin lesion ": 2.854450858334013, "Spleen disorder ": 54.863923691472905, "Splenic infarction ": 33.47677254032047, "Splenomegaly ": 88.1432121065915, "Squamous cell carcinoma ": 60.1541555209201, "Squamous cell carcinoma of skin ": 55.94068966087306, "Therapeutic response decreased ": 7.238686517410013, "Therapy non-responder ": 7.885079999042761, "Therapy partial responder ": 22.2700994895276, "Thrombocytopenia ": 11.264604819673236, "Thrombocytosis ": 30.277601068635413, "Tuberculosis ": 10.009631931355113, "Weight increased ": 2.353626139839766, "White blood cell count increased ": 14.502731502832216, "Withdrawal syndrome ": 2.190008556525572}
\ No newline at end of file
+{"Abdominal abscess": 9.800777945523771, "Abscess": 12.764668360260698, "Abscess limb": 16.372372165500735, "Acute respiratory failure": 2.1405611589376923, "Adenocarcinoma of colon": 13.213144566182264, "Administration site erythema": 4.554529500234091, "Administration site reaction": 9.763824171678475, "Alanine aminotransferase increased": 2.838202441054841, "Alveolitis": 6.006661137234706, "Anaphylactic reaction": 2.1944541262876283, "Anaphylactoid reaction": 2.507135248392041, "Aneurysm": 3.273253783625714, "Aortic aneurysm": 2.4127672812855714, "Aortic dissection": 12.179535981589588, "Aphthous ulcer": 6.505592523439203, "Appendicitis": 3.035335615124995, "Arthritis": 4.569417940440983, "Arthritis bacterial": 52.76024810048053, "Arthritis infective": 12.05821172968112, "Aspergillus infection": 3.69058786739076, "Bacteraemia": 2.070514625101549, "Bacterial sepsis": 4.028245386811367, "Basal cell carcinoma": 6.236262149225132, "Blood bilirubin unconjugated increased": 8.623810047461427, "Blood cholesterol increased": 4.131502110766711, "Blood fibrinogen decreased": 28.468541717910824, "Blood triglycerides increased": 3.867771006162711, "Breast cancer": 2.3550505574498497, "Bronchitis": 2.9863536395319032, "Bursitis infective": 45.54848835879347, "C-reactive protein decreased": 20.93123357726968, "Cardiovascular insufficiency": 9.13500907927468, "Cellulitis": 6.72720075301463, "Cholecystitis": 2.118152357192602, "Cholecystitis acute": 2.7385345141903987, "Colectomy": 4.2673991482481, "Complement factor C3 decreased": 51.200933697761, "Complement factor C4 decreased": 68.87987827367803, "Conjunctivitis": 2.7055469781469523, "Cutaneous vasculitis": 5.665131496528173, "Cyst": 2.271671885219236, "Cystitis": 2.347885195989741, "Demyelination": 3.915363965810154, "Dermo-hypodermitis": 46.80242353051369, "Device difficult to use": 4.17605679818807, "Device related infection": 8.413927594355155, "Diverticular perforation": 123.6293763508997, "Diverticulitis": 25.15011757391077, "Diverticulum": 4.384315561399317, "Diverticulum intestinal": 3.394487189179016, "Drug delivery system malfunction": 4.03292969688447, "Empyema": 12.173498664151271, "Encephalitis": 2.117772511165185, "Encephalitis herpes": 10.240426475032592, "Endocarditis": 7.1146791038741934, "Eosinophil count increased": 2.2028935510378407, "Eosinophilia": 2.520100570989864, "Epiglottitis": 18.873220888636816, "Erysipelas": 20.862966894416907, "Escherichia urinary tract infection": 4.2103890123311, "Exposure via skin contact": 13.948521189002262, "Extremity necrosis": 18.15597222859984, "Fournier's gangrene": 2.513416677689425, "Furuncle": 2.4904993207679382, "Gamma-glutamyltransferase increased": 2.728626060531597, "Gangrene": 2.341077561302919, "Gastric perforation": 6.682678226162834, "Gastrointestinal inflammation": 4.278317981356002, "Gastrointestinal perforation": 8.987047724134243, "Giant cell arteritis": 15.951950522449064, "Gingivitis": 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3.829199116227006, "Injection site erythema": 2.257966023377921, "Injection site haemorrhage": 2.9186781505040065, "Injection site hypersensitivity": 11.38261021857491, "Injection site oedema": 4.682411581971213, "Injection site pruritus": 2.565550184029449, "Injection site rash": 8.079275662635757, "Injection site reaction": 4.806494682969876, "Injection site urticaria": 5.933500188185027, "Injury associated with device": 6.304676942422692, "Intentional product use issue": 10.91549229614474, "Intercepted product storage error": 91.21687460292188, "Interleukin level increased": 38.13068723337594, "Intermittent claudication": 5.843876912136647, "International normalised ratio decreased": 2.2927163213332338, "Intervertebral discitis": 23.95114763621588, "Intestinal haemorrhage": 2.283686533977654, "Intestinal ischaemia": 3.0772145372945947, "Intestinal perforation": 13.505755687533508, "Invasive ductal breast carcinoma": 3.565812878482105, "Iritis": 3.912833224339235, "Joint effusion": 2.022844472369268, "Juvenile idiopathic arthritis": 13.54589143475627, "Keratitis": 4.898466339706872, "Large intestine perforation": 23.015201243826013, "Leukopenia": 7.2728547456471535, "Lipids increased": 14.94715758314772, "Liver abscess": 8.000961867005916, "Liver function test increased": 5.07949444538832, "Localised infection": 4.934769376891997, "Loss of therapeutic response": 24.84926502039356, "Low density lipoprotein increased": 11.423787143884557, "Lower respiratory tract infection": 2.680381432869446, "Lung abscess": 9.556916234759017, "Lung adenocarcinoma": 9.562035404477918, "Lung disorder": 2.0683012289970253, "Lung neoplasm": 8.880047599612354, "Lung neoplasm malignant": 2.062580386261799, "Lymphocytosis": 4.452919435258999, "Lymphopenia": 3.87687009293732, "Malignant melanoma": 6.833483133665967, "Melanocytic naevus": 4.603002156552246, "Meningitis": 2.9901200779088395, "Mouth ulceration": 4.2701979709081535, "Multiple organ dysfunction syndrome": 3.063184645103107, "Necrosis": 2.748046739585948, "Necrotising fasciitis": 17.43327472683876, "Needle issue": 7.480144202681702, "Neoplasm": 5.299096410060584, "Neuromyelitis optica spectrum disorder": 10.63931639279414, "Neutropenia": 6.792491972511296, "Neutrophil count decreased": 2.7030930695266155, "Neutrophilia": 4.068244101586006, "No adverse event": 12.434792501858592, "Off label use": 3.168185132643041, "Oral herpes": 3.2167770115129266, "Oral mucosal blistering": 2.6376016303247254, "Organising pneumonia": 3.0774313535936524, "Osteitis": 12.128035476440212, "Osteomyelitis": 6.098069167722163, "Otitis media": 2.28366290665996, "Ovarian cancer": 2.249804784902038, "Pancreatitis acute": 2.469714726131123, "Panniculitis": 5.676562605370352, "Paronychia": 4.034067741970288, "Peripheral ischaemia": 7.700568925744635, "Peritonitis": 18.309373716437896, "Phlebitis": 2.584713732783365, "Pneumocystis jirovecii pneumonia": 4.352298166447323, "Pneumonia": 2.5636993040206897, "Pneumonia pneumococcal": 13.88937290433322, "Poor quality product administered": 2.2350768856200007, "Postoperative wound infection": 3.5317002388020224, "Product storage error": 4.376884475069375, "Psoriasis": 2.285435652893539, "Pulmonary fibrosis": 2.313453030865216, "Pulmonary tuberculosis": 6.056390365464915, "Pulpitis dental": 25.17143602732152, "Pustule": 4.75500304798542, "Pyelonephritis": 3.8594621780833593, "Pyoderma gangrenosum": 11.484992139874665, "Renal abscess": 14.472874538595448, "Renal function test abnormal": 2.5913103854349058, "Respiratory tract infection": 3.2535090173111576, "Rheumatoid arthritis": 3.8882814236022334, "Rheumatoid nodule": 15.54361075446031, "Sepsis": 5.333344115234852, "Septic shock": 6.59624662890932, "Skin infection": 8.2870042268022, "Skin necrosis": 2.6450791095626647, "Skin reaction": 4.598830024059256, "Skin ulcer": 6.270457968643869, "Small intestinal perforation": 7.817520158408565, "Soft tissue infection": 18.61854210485971, "Squamous cell carcinoma": 2.428719251920948, "Staphylococcal sepsis": 11.303652592899368, "Streptococcal sepsis": 21.42853484533416, "Stress fracture": 5.088977555543065, "Subcutaneous abscess": 8.388225142965503, "Sudden hearing loss": 2.092164880108192, "Syringe issue": 11.568056652977203, "Tenosynovitis": 3.619049499191208, "Thrombocytopenia": 2.7428034327961184, "Thyroid cancer": 2.865424938470897, "Tonsillitis": 2.9881675084516326, "Tooth abscess": 4.367795401569158, "Tooth disorder": 2.7615068310334365, "Transaminases increased": 5.400556593888021, "Tuberculosis": 5.429770079119413, "Ulcerative keratitis": 7.243480896177891, "Upper respiratory tract infection": 3.010642611066657, "Urinary tract infection": 3.201724112233268, "Urosepsis": 3.101143374602401, "Urticaria": 2.155944132947851, "Vasculitis": 4.061397453845896, "Wound infection": 4.690500675563875}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/965.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/965.json
index 6b7844374d9..682ad68b601 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/965.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/965.json
@@ -1 +1 @@
-{"Abdominal discomfort ": 4.930057737658152, "Abdominal distension ": 6.12684179855822, "Abdominal pain ": 3.1279214254422585, "Abdominal pain upper ": 5.3542964623279605, "Amylase increased ": 5.673064002975826, "Blood glucose decreased ": 2.552622505883805, "Blood glucose increased ": 5.988169858558681, "Cholecystitis ": 7.920465092458788, "Cholelithiasis ": 10.996824415257352, "Constipation ": 6.815035473134768, "Decreased appetite ": 4.632025118973979, "Dehydration ": 3.491864236712261, "Diabetes mellitus inadequate control ": 7.759231661479383, "Diabetic ketoacidosis ": 3.6290865816322255, "Diabetic retinopathy ": 12.878447252421928, "Diarrhoea ": 3.491907372613593, "Drug intolerance ": 2.38673373486242, "Dysgeusia ": 3.839344309021025, "Dyspepsia ": 8.749753250089785, "Eructation ": 36.38451289005084, "Feeding disorder ": 2.9923371106013543, "Flatulence ": 12.224186674369385, "Gastritis ": 3.3990479968774543, "Gastrointestinal disorder ": 5.848672965309435, "Gastrooesophageal reflux disease ": 3.5896790279573865, "Glycosylated haemoglobin increased ": 24.10586970371603, "Impaired gastric emptying ": 31.856143089881357, "Inappropriate schedule of product administration ": 3.2822261274796354, "Increased appetite ": 7.14137344115537, "Intestinal obstruction ": 3.5898713116632472, "Lipase increased ": 8.741235794760204, "Nausea ": 4.606891516615754, "Off label use ": 3.226276345254073, "Pancreatic carcinoma ": 3.893633522379389, "Pancreatitis ": 19.22416033733675, "Pancreatitis acute ": 14.244427534332155, "Product taste abnormal ": 7.9344464610669885, "Surgery ": 2.508260985033779, "Taste disorder ": 3.243680067086532, "Vomiting ": 5.612713599001174, "Weight decreased ": 4.490104063372239, "Weight increased ": 2.25135744560894}
\ No newline at end of file
+{"Acute myocardial infarction": 10.607729548212124, "Arteriosclerosis": 25.98107655929585, "Atrial fibrillation": 5.488265948738767, "Cardiac arrest": 4.991640345160891, "Cardiac disorder": 13.679936150459982, "Cardiac failure": 7.929830035832895, "Cardiac failure congestive": 79.5102072089395, "Cardiac operation": 52.14395134093398, "Cardio-respiratory arrest": 13.002599755829332, "Cardiomyopathy": 18.6057005735506, "Cardiovascular disorder": 15.261591344174978, "Cerebrovascular accident": 22.749871311134672, "Coronary artery bypass": 47.88629246673455, "Coronary artery disease": 51.15801394968886, "Death": 2.628977326013082, "Diabetes mellitus inadequate control": 8.764515565412617, "Fluid retention": 9.649490985024938, "Hypertension": 2.380579041389812, "Myocardial infarction": 45.30991079890095, "Myocardial ischaemia": 23.74918556953053, "Oedema": 4.548903594873108, "Transient ischaemic attack": 10.861642518248212, "Weight increased": 4.6438363895354575}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/966.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/966.json
index 28dd0f10146..b929259695a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/966.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/966.json
@@ -1 +1 @@
-{"Acute myeloid leukaemia ": 21.11643262684059, "Acute myeloid leukaemia recurrent ": 145.84955215907334, "Cardiac failure ": 4.074940484846491, "Cytopenia ": 26.661558419767022, "Death ": 2.6702350341078445, "Diarrhoea ": 2.0038783884467426, "Dysphagia ": 4.109702489882915, "Electrocardiogram QT prolonged ": 7.2936575098600755, "Febrile neutropenia ": 11.25544469682487, "Infection ": 3.195243809750964, "Malignant neoplasm progression ": 3.180868996190057, "Neutropenia ": 2.379263722207327, "Platelet count decreased ": 2.519442343503037, "Sepsis ": 5.740105490322061, "Thrombocytopenia ": 3.3535040168832606}
\ No newline at end of file
+{"Agitation": 4.612722887600406, "Altered state of consciousness": 8.57877698802745, "Crying": 49.98426336553884, "Cyanosis": 38.878018963489815, "Diarrhoea": 3.822268785490418, "Febrile convulsion": 94.87516685825372, "Haematochezia": 30.079045065129765, "Hypotonia": 49.32153108343879, "Hypotonic-hyporesponsive episode": 158.4509413574325, "Injection site erythema": 4.666092149636292, "Injection site oedema": 67.9143168822047, "Injection site warmth": 5.178936562105896, "Intussusception": 110.65632499809968, "Lethargy": 5.092917150057466, "Pallor": 31.686440174265208, "Rotavirus infection": 278.5709048829182, "Seizure": 4.156027876445932, "Somnolence": 2.3630489561976726, "Unresponsive to stimuli": 19.373948202673677, "Vomiting": 3.4203942932327216}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/967.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/967.json
index d695a43010c..97755471c35 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/967.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/967.json
@@ -1 +1 @@
-{"Alopecia ": 8.309080153397142, "Amenorrhoea ": 24.40258963306568, "Condition aggravated ": 5.51454914662635, "Depressed mood ": 7.165686182664994, "Depression ": 3.658163558345122, "Heavy menstrual bleeding ": 18.50896560490084, "Hot flush ": 18.619776393643296, "Intermenstrual bleeding ": 25.013564563326437, "Irritability ": 6.512521867210966, "Mood swings ": 15.989526844285349, "Uterine haemorrhage ": 229.40645517067435, "Uterine leiomyoma ": 107.13312254126102, "Vaginal haemorrhage ": 13.048797638803364, "Weight increased ": 6.999568246078738}
\ No newline at end of file
+{"Autism spectrum disorder": 218.0674426706356, "Dehydration": 10.28864473108436, "Diarrhoea": 2.681655817197245, "Gastroenteritis": 134.8481763047518, "Intestinal obstruction": 551.3179136022165, "Intussusception": 607.3828774637363, "Language disorder": 167.08595571253818, "Metal poisoning": 1116.1260303304462, "Neurological symptom": 123.43464368199488, "Pyrexia": 2.348482329690315, "Vomiting": 2.496358695890443}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/968.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/968.json
index 649b8e32d0e..f1a9a400fd8 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/968.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/968.json
@@ -1 +1 @@
-{"Alopecia ": 9.636692109612964, "Asthenia ": 3.490035478264735, "Constipation ": 5.365902569482233, "Diarrhoea ": 6.040365679768657, "Disease progression ": 7.583682373247642, "Febrile neutropenia ": 7.74948614293307, "Inappropriate schedule of product administration ": 5.937126614629556, "Nausea ": 2.032819325315852, "Neutropenia ": 17.931072852680213, "Weight decreased ": 2.3863244987262107, "Weight fluctuation ": 118.35994500566149}
\ No newline at end of file
+{"Abdominal distension": 3.046152572389491, "Abdominal mass": 39.91776686321335, "Abdominal pain": 4.171482174602547, "Abdominal rigidity": 9.674878005715062, "Abdominal tenderness": 8.782813809642887, "Abnormal faeces": 19.91638527895577, "Accidental underdose": 48.418433487119, "Acidosis": 3.917466984994348, "Anal fissure": 13.289277331478871, "Apathy": 4.533970063022273, "Apnoea": 14.852593495546712, "Appendicectomy": 42.45810536472584, "Appendix disorder": 24.6155580379301, "Asphyxia": 3.839890286940167, "Barium enema": 2708.880104596388, "Breath sounds abnormal": 3.617247116940925, "Bronchiolitis": 11.84755215591199, "Bronchitis": 2.0553558395949034, "Chapped lips": 8.18730910684673, "Choking": 5.406119733405012, "Colitis": 2.589563341612862, "Combined immunodeficiency": 291.2914584332081, "Constipation": 2.070468506815821, "Crying": 42.32100871779234, "Cyanosis": 5.362106778833264, "Cytomegalovirus infection": 2.1144566738048844, "Dairy intolerance": 105.22214826210984, "Decreased activity": 3.141866625260112, "Dehydration": 8.224660605804559, "Dermatitis atopic": 7.809937662654876, "Dermatitis diaper": 51.23444185689549, "Developmental delay": 2.6792810252565418, "Diarrhoea": 6.856862797649604, "Diarrhoea haemorrhagic": 29.65236647421152, "Diet refusal": 82.95499891934783, "Ear infection": 3.7530443921108825, "Enema administration": 3157.629152286781, "Enteritis": 17.220739490262165, "Enterocolitis": 3.9780205953263583, "Expired product administered": 2.38477974434178, "Eye movement disorder": 3.0815105586530165, "Faeces discoloured": 23.57647510891971, "Faeces pale": 11.023061783310832, "Faeces soft": 9.737524210947472, "Failure to thrive": 12.46705238011334, "Febrile convulsion": 4.8624118832226975, "Flatulence": 6.612124913330795, "Fluid intake reduced": 21.33518026677384, "Fontanelle bulging": 66.65174812380684, "Food allergy": 3.811296640628752, "Frequent bowel movements": 4.446760420273724, "Gastroenteritis": 44.20771096311233, "Gastroenteritis 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3.372379828043359, "Intestinal perforation": 2.3091471269116965, "Intestinal resection": 28.288548034055815, "Intussusception": 2624.760502157841, "Irritability": 14.852156507491006, "Irritability postvaccinal": 2.4578526523356543, "Kawasaki's disease": 257.7779281044644, "Lactose intolerance": 12.131904994862603, "Laparotomy": 149.57965230494827, "Lethargy": 5.142984259217696, "Listless": 4.227785841512978, "Meningitis": 3.6612257708683407, "Metabolic acidosis": 2.374378329602276, "Milk allergy": 216.33844959140868, "Mucous stools": 198.6830155109137, "Myocardial injury": 11.973287805411006, "Occult blood positive": 14.636764576177596, "Otitis media": 8.663267440188225, "Pallor": 10.182861199158278, "Petechiae": 2.2613576401587507, "Pharyngeal erythema": 13.229747586236387, "Poor feeding infant": 18.78964523807031, "Poor quality sleep": 2.753218166522784, "Product administered to patient of inappropriate age": 21.06347028043164, "Rectal haemorrhage": 2.403234445151947, "Regurgitation": 47.10181395724627, "Respiratory syncytial virus infection": 5.095594102355359, "Restlessness": 6.300355761948159, "Retching": 2.35156960741533, "Rhinitis": 3.664601465994487, "Rotavirus infection": 1864.961970002797, "Rotavirus test positive": 10751.495924523562, "Salmonellosis": 21.529745053860704, "Screaming": 30.956921983246534, "Secondary transmission": 137.78317015243871, "Selective eating disorder": 16.760705427012635, "Small intestinal obstruction": 3.438239630486306, "Sudden infant death syndrome": 45.34884902881807, "Surgery": 9.262282280071972, "Tearfulness": 4.29196254850502, "Thrombocytopenic purpura": 34.92222192097596, "Tooth malformation": 704.8909425198522, "Transfusion": 2.1698440744487995, "Underdose": 5.201048088896739, "Unresponsive to stimuli": 3.65574609356021, "Upper respiratory tract infection": 6.1183450931921, "Urine output decreased": 9.802830415513, "Vaccination error": 23.7675830682938, "Vaccination failure": 4.128893392982556, "Viral infection": 3.917497209711664, "Vomiting": 5.792909386145133, "Vomiting projectile": 40.69756006526693, "Weight gain poor": 50.16241960286814}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/969.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/969.json
index c796b259212..2edd00e0c72 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/969.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/969.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 3.272590419130843, "Altered state of consciousness ": 11.7634952913407, "Aspartate aminotransferase increased ": 4.372499876593629, "Blood creatinine increased ": 7.059129899999058, "Blood potassium increased ": 33.017386769864274, "Blood pressure decreased ": 7.826327020489997, "Blood urea increased ": 16.712761217307744, "Cardiac failure ": 15.724027385228675, "Cardiac failure chronic ": 94.06503655237576, "Cardiac failure congestive ": 3.5559463588167457, "Cerebral infarction ": 24.206126142812487, "Dehydration ": 22.652422742243317, "Drug interaction ": 2.188201575445348, "Glomerular filtration rate decreased ": 10.993233127056232, "Hepatic encephalopathy ": 30.619023253576987, "Hepatic function abnormal ": 12.598073836728853, "Hyperkalaemia ": 19.29357378860546, "Hypernatraemia ": 314.1517471146926, "Hypokalaemia ": 6.69753829212873, "Hyponatraemia ": 6.57251775209672, "Hypotension ": 3.744482335896227, "Incorrect dose administered ": 3.77453488412448, "Liver disorder ": 4.238596509568318, "Multiple organ dysfunction syndrome ": 6.9206296233715205, "Oedema peripheral ": 3.254683779829601, "Platelet count decreased ": 2.003277381202369, "Pleural effusion ": 5.187733378137275, "Product use in unapproved indication ": 2.0534059512914205, "Rapid correction of hyponatraemia ": 5993.302475013472, "Renal failure ": 2.63273681633115, "Renal impairment ": 22.26499340303588, "Shock ": 7.025387275642692, "Thirst ": 10.199955214385623}
\ No newline at end of file
+{"Drug withdrawal syndrome": 51.14117313413747, "Impulse-control disorder": 1163.3644995102547}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/97.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/97.json
index 682a22b5359..ce54a48a2e4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/97.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/97.json
@@ -1 +1 @@
-{"Hormone-refractory prostate cancer ": 357.33944216139383, "Malignant neoplasm progression ": 5.112240598587916, "Prostate cancer metastatic ": 383.29016688632737, "Prostatic specific antigen increased ": 97.51335005611386, "Rash ": 5.321744298382776}
\ No newline at end of file
+{"Completed suicide": 158.5298852551079}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/970.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/970.json
index 0100dea7f2e..44790637a86 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/970.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/970.json
@@ -1 +1 @@
-{"Blood lactic acid increased ": 300.6426071405326, "Diplopia ": 79.86579112512173, "Dysphagia ": 25.71960913371485, "Eyelid ptosis ": 300.42700844247446, "Lactic acidosis ": 30.76625312782692, "Lipodystrophy acquired ": 540.0979097647316, "Mitochondrial toxicity ": 1873.104789775333, "Ophthalmoplegia ": 798.8004375898169}
\ No newline at end of file
+{"Accidental underdose": 15.58824161343866, "Acute myeloid leukaemia": 2.0236207879988832, "Adverse drug reaction": 2.6676802329273364, "Adverse event": 27.40599369339656, "Alanine aminotransferase increased": 5.712813801765201, "Anaemia": 6.530667060772686, "Ascites": 4.4295438950554695, "Aspartate aminotransferase increased": 4.882063655985347, "Asthenia": 2.229374742218846, "Blood alkaline phosphatase increased": 2.566268309356594, "Blood creatinine increased": 7.525438598676626, "Blood magnesium decreased": 33.12169306081485, "Blood potassium decreased": 5.754090876297713, "Blood sodium decreased": 2.591703245579112, "Blood test abnormal": 8.182961645812316, "Carbohydrate antigen 125 increased": 822.8072402865545, "Constipation": 5.132886110970955, "Cytopenia": 2.254231733222221, "Death": 3.946058961384429, "Decreased appetite": 3.090329654440758, "Dehydration": 5.042855361637016, "Drug intolerance": 2.3966967651935382, "Dysgeusia": 8.58117751879402, "Full blood count abnormal": 11.69700743732657, "Glomerular filtration rate decreased": 4.193727772477089, "Haematocrit decreased": 5.8683464905226925, "Haematotoxicity": 4.10209729463261, "Haemoglobin decreased": 8.746314146323266, "Hernia": 6.633738957093603, "Hypersomnia": 2.5809900352431043, "Hypertransaminasaemia": 5.010802015573565, "Hypophagia": 11.623187792810995, "Illness": 2.1399406483950565, "Intentional underdose": 12.42558380467375, "Intestinal obstruction": 15.398804757094736, "Laboratory test abnormal": 14.57198169930636, "Liver function test abnormal": 3.320690882441154, "Liver function test increased": 6.4920965469468825, "Malignant neoplasm progression": 18.765646195545816, "Malnutrition": 4.121488334961979, "Metastases to central nervous system": 9.00918446382834, "Myelodysplastic syndrome": 8.928459387780606, "Nausea": 2.212067674638511, "Neoplasm": 5.61590484322116, "Neuropathy peripheral": 4.57841779912859, "Neutropenia": 2.1864040437578307, "Ovarian cancer": 6.22399101680361, "Ovarian cancer metastatic": 61.51599018863623, "Ovarian cancer recurrent": 719.381654576542, "Photosensitivity reaction": 6.377257826963176, "Platelet count decreased": 8.9070094950562, "Pleural effusion": 2.0359484052900467, "Prescribed underdose": 16.198406409227303, "Product dose omission issue": 8.629674163290986, "Product use in unapproved indication": 2.1135210026236058, "Recurrent cancer": 42.9710601906414, "Red blood cell count decreased": 18.509743577598037, "Renal function test abnormal": 28.269337352129163, "Renal impairment": 2.620265014411065, "Small intestinal obstruction": 27.70613270006536, "Sunburn": 13.300510090289832, "Surgery": 4.27672475825635, "Taste disorder": 5.807960413659807, "Therapy partial responder": 15.494220586701829, "Thrombocytopenia": 4.231206897866096, "Transaminases increased": 2.0768802844656045, "Transfusion": 9.138928960232992, "Tumour marker increased": 27.72934008417512, "Underdose": 11.124479474940012, "Urinary tract infection": 2.239860888398015, "Vomiting": 2.1140281090896984, "White blood cell count decreased": 4.619791886356677}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/971.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/971.json
index 0f3ba7467e2..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/971.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/971.json
@@ -1 +1 @@
-{"Myelosuppression ": 25.945340301620405, "Off label use ": 36.22968281793808}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/972.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/972.json
index d867c3cd42a..1efce20fc1d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/972.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/972.json
@@ -1 +1 @@
-{"Acute kidney injury ": 4.392615441494683, "Bradycardia ": 11.208902794701231, "Hyperkalaemia ": 18.62037132838603, "Hypoglycaemia ": 13.641553716214377, "Hypotension ": 5.807094665640416}
\ No newline at end of file
+{"Caesarean section": 15.033093308490317, "Central venous catheterisation": 167.16862441343702, "Complication of pregnancy": 124.7474474094501, "Condition aggravated": 4.563913703395952, "Device related infection": 30.379321726271023, "Drug ineffective": 3.36930180167827, "Drug ineffective for unapproved indication": 26.010284677450294, "Hereditary angioedema": 384.81613983022, "Hysterectomy": 22.422541020961425, "Illness": 2.6508149923534488, "Incorrect route of product administration": 6.665687103122151, "Infection": 2.3199258258702296, "Insurance issue": 52.37275706918357, "Intentional product use issue": 67.23278723665948, "Kidney infection": 16.055461176545894, "Laryngeal oedema": 17.31579009665415, "Maternal exposure during breast feeding": 16.68983578534393, "Maternal exposure during pregnancy": 8.816119739164813, "Nephrolithiasis": 8.539055056641965, "Pharyngeal swelling": 134.7075176265005, "Pneumonia": 2.99532969122357, "Poor venous access": 92.5799569758312, "Product dose omission issue": 6.0486406563471045, "Product use in unapproved indication": 9.749357703484462, "Respiratory tract infection": 4.417830492592935, "Respiratory tract oedema": 268.59597081081745, "Road traffic accident": 3.083005395505062, "Sepsis": 5.507044753008927, "Sinusitis": 6.101029614380689, "Staphylococcal infection": 4.8779349148566284, "Stress": 5.023775538339215, "Surgery": 4.581646733683935, "Therapeutic product effect incomplete": 12.941331693397478, "Throat tightness": 3.8643172316644057, "Thrombosis": 6.541343816846738, "Tooth infection": 14.606423592705545, "Underdose": 20.15351565744619, "Upper respiratory tract infection": 4.706274534941705, "Vascular access complication": 874.2489271379047, "Vascular access site complication": 13158.557593359932, "Vascular access site infection": 4122.597864893069, "Vascular device infection": 48.001159839670464, "Vein rupture": 80.15516947555281, "Weight fluctuation": 41.670516432440685}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/973.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/973.json
index c6680e13ee6..ae038ff1fed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/973.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/973.json
@@ -1 +1 @@
-{"Abdominal distension ": 5.957598101981265, "Abdominal pain ": 3.4936723303290007, "Abdominal pain upper ": 3.821252996149209, "Abortion ": 5.70146086621288, "Abortion spontaneous ": 2.41651665995451, "Amylase increased ": 7.238104714883996, "Appendicitis ": 3.4932959877051197, "Appetite disorder ": 24.66198093097622, "Autoimmune thyroiditis ": 2.2262395950530425, "Bile duct stone ": 15.290520358307775, "Biliary colic ": 47.086584547086616, "Breath odour ": 10.363382417658302, "Cholangitis ": 3.1651063863210624, "Cholecystectomy ": 29.167290568733552, "Cholecystitis ": 33.63457735568049, "Cholecystitis acute ": 16.040874763471027, "Cholelithiasis ": 49.67993708648, "Colitis ": 2.0367498075175074, "Constipation ": 7.9996044600362435, "Dehydration ": 3.79303399970223, "Depressed mood ": 2.299246972206367, "Depression suicidal ": 4.852419087068935, "Depressive symptom ": 5.487649066973128, "Device defective ": 9.49710710207634, "Device delivery system issue ": 10.632177693672356, "Device failure ": 4.389112637582569, "Device issue ": 3.0876532440296365, "Device malfunction ": 5.053351282439603, "Device mechanical issue ": 31.536713402270976, "Diarrhoea ": 3.076554733221867, "Diarrhoea haemorrhagic ": 3.903181212810469, "Disability ": 3.019790070550251, "Diverticulitis ": 3.9104814756767343, "Drug delivery system issue ": 10.475156925010918, "Drug diversion ": 7.625587751494669, "Drug dose titration not performed ": 77.11765511333691, "Drug effect less than expected ": 13.47457734922356, "Drug titration error ": 38.86317134855557, "Dry mouth ": 2.6159183987498835, "Dyspepsia ": 8.065031145930122, "Early satiety ": 15.180222425405, "Eructation ": 46.19149517450522, "Flatulence ": 9.189088739427334, "Food aversion ": 9.9954406755654, "Food craving ": 67.90899668149329, "Food intolerance ": 3.9593160360086697, "Food poisoning ": 7.74825804228397, "Gallbladder disorder ": 8.285145149548281, "Gallbladder operation ": 17.142103989999185, "Gastritis ": 8.102702654106327, "Gastroenteritis ": 4.977572882944337, "Gastrointestinal necrosis ": 5.953425285382934, "Gastrooesophageal reflux disease ": 4.842495478386171, "Heart rate increased ": 2.044610068856188, "Hepatic steatosis ": 3.3003074561353016, "Hiccups ": 3.8060620152388194, "Hip surgery ": 5.885408695448563, "Hunger ": 37.143218299659054, "Hyperchlorhydria ": 9.95746035965688, "Hypoglycaemic unconsciousness ": 3.59117805970665, "Illness ": 2.102160483761197, "Impaired gastric emptying ": 9.82577811679446, "Inappropriate schedule of product administration ": 3.6130814909044062, "Incorrect dose administered by device ": 8.670079993897534, "Increased appetite ": 14.291121642029738, "Injection site bruising ": 17.658288170524308, "Injection site discolouration ": 28.08518741703107, "Injection site discomfort ": 2.469739815846446, "Injection site erythema ": 9.519961246906144, "Injection site haematoma ": 2.968113775830008, "Injection site hypersensitivity ": 80.45829811070433, "Injection site induration ": 5.970067784471712, "Injection site irritation ": 48.73667426736208, "Injection site mass ": 11.623357067156014, "Injection site oedema ": 2.1014673620694597, "Injection site pruritus ": 19.901706532493257, "Injection site rash ": 48.78521392180695, "Injection site reaction ": 2.829861355947425, "Injection site swelling ": 2.678936252607946, "Injection site urticaria ": 45.60513135873133, "Injection site vesicles ": 9.071992541974394, "Intentional dose omission ": 3.6304570118362287, "Intestinal obstruction ": 2.91422178720769, "Intracranial pressure increased ": 2.4364285471812592, "Lack of satiety ": 362.8339976282431, "Lipase increased ": 15.057639001971657, "Liquid product physical issue ": 9.349475343780858, "Liver function test increased ": 2.0251056417235325, "Nausea ": 3.63326601514742, "Nephrolithiasis ": 2.642365666476556, "Obstructive pancreatitis ": 26.32632903703612, "Oedematous pancreatitis ": 15.68004635983038, "Pancreatic carcinoma ": 2.896273958730941, "Pancreatic carcinoma metastatic ": 2.9478176547389245, "Pancreatic cyst ": 13.737458709428653, "Pancreatic disorder ": 7.133313633904936, "Pancreatitis ": 27.253388124166133, "Pancreatitis acute ": 11.630526219325995, "Pancreatitis necrotising ": 11.273877099815111, "Papillary thyroid cancer ": 22.8405449442475, "Prescription drug used without a prescription ": 10.492383405543332, "Product communication issue ": 12.65069974537242, "Product odour abnormal ": 4.758113216793893, "Product quality issue ": 5.8477870037826944, "Product storage error ": 2.6071750114245624, "Regurgitation ": 5.1606517877427525, "Renal colic ": 5.149954318320227, "Self-injurious ideation ": 5.762730828408215, "Skin odour abnormal ": 6.3898460015954255, "Skin reaction ": 2.556655108922498, "Small intestinal obstruction ": 2.6217734919539297, "Suicidal ideation ": 3.968819433549519, "Surgery ": 4.884745912418875, "Suspected counterfeit product ": 10.071801270447484, "Thyroid cancer ": 10.415305713153726, "Thyroid mass ": 18.97454354213747, "Vomiting ": 4.034125696313054, "Weight increased ": 3.925125353851069, "Weight loss poor ": 965.4894508152456, "Wrong technique in product usage process ": 3.17691861269496, "Yellow skin ": 2.0406543872942104}
\ No newline at end of file
+{"Drug ineffective": 6.815374271909445, "Off label use": 7.966863807306713, "Product use issue": 25.461701209919077, "Seizure": 15.029531007717354, "Therapy non-responder": 34.21217423825758, "Treatment failure": 110.27445421657272}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/974.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/974.json
index 73739824f09..c73d1e356d2 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/974.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/974.json
@@ -1 +1 @@
-{"Cardiac failure ": 4.535799713528884, "Disease progression ": 4.406367710131015, "Electrocardiogram QT prolonged ": 10.286915074612551, "Lipase increased ": 47.84433307375701, "Neutropenia ": 3.896416019654568, "Off label use ": 2.014428392097531, "Pancreatitis ": 11.790948559960835, "Pancytopenia ": 10.519882618710938, "Platelet count decreased ": 8.565671453799533, "Thrombocytopenia ": 13.530184539929612, "White blood cell count decreased ": 3.248883719516391}
\ No newline at end of file
+{"Off label use": 6.394513843918521}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/975.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/975.json
index 7a27c364dd3..9633e838d84 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/975.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/975.json
@@ -1 +1 @@
-{"Anxiety ": 2.7059062670482086, "Asthma ": 14.51042168383211, "Chest discomfort ": 7.563712124875466, "Chronic obstructive pulmonary disease ": 11.00004518009037, "Cough ": 4.198131622987876, "Cyanosis ": 17.006274048108452, "Depression ": 2.6814969961020743, "Dyspnoea ": 2.839411147836903, "Dyspnoea exertional ": 14.482065994242468, "Emphysema ": 44.10726862854626, "Fall ": 2.58830327345888, "Gait disturbance ": 2.6081291657201287, "Hiatus hernia ": 39.99138034595639, "Hypoaesthesia ": 3.45494405934379, "Infection ": 5.994181775268377, "Insomnia ": 2.8428971111175256, "Overdose ": 5.28533097805287, "Pneumonia ": 4.802134285370815, "Wheezing ": 8.824417980937305}
\ No newline at end of file
+{"Acute graft versus host disease": 10.048406242167546, "Acute myeloid leukaemia": 16.14233706205119, "Anaemia": 10.02495019478464, "BK virus infection": 23.62533352555422, "Basal cell carcinoma": 15.14115750571396, "Basophil count increased": 93.88774821125796, "Blood lactate dehydrogenase increased": 5.94750162090218, "Bronchopulmonary aspergillosis": 12.569243110210758, "Chronic graft versus host disease": 29.79428541269381, "Concomitant disease aggravated": 10.24179554525715, "Cytomegalovirus infection": 15.936931540109356, "Cytomegalovirus infection reactivation": 27.362096545156287, "Cytopenia": 25.40575055785961, "Disease recurrence": 4.717073933498607, "Epstein-Barr virus infection reactivation": 36.77429039852652, "Graft versus host disease": 7.164081477653011, "Haematocrit decreased": 11.088714795018666, "Haematoma": 2.144443065236377, "Haemoglobin abnormal": 20.69857129316561, "Haemoglobin decreased": 12.130477059089282, "Herpes simplex": 9.455190357220689, "Leukocytosis": 21.679110582355044, "Leukopenia": 2.323811298473147, "Lymphocyte count increased": 24.70879291504317, "Lymphopenia": 4.17910572908198, "Malignant neoplasm progression": 3.025916556907649, "Melaena": 2.1277394915161216, "Monocyte count increased": 22.491540704952385, "Myelofibrosis": 150.31914257748258, "Neutrophil count increased": 23.806962190466784, "Neutrophilia": 26.978614278571342, "Night sweats": 2.9029705271776423, "Pancytopenia": 3.4887651396967585, "Platelet count abnormal": 41.54108764443495, "Platelet count decreased": 10.175209854682803, "Platelet count increased": 25.26832647194433, "Pleural effusion": 2.365221118264864, "Pneumonia": 2.2340735925975173, "Primary myelofibrosis": 453.3999335105938, "Product use in unapproved indication": 14.250718010305311, "Product use issue": 2.079218485591212, "Pulmonary tuberculosis": 14.872243484455126, "Red blood cell count decreased": 6.181037183481511, "Red cell distribution width increased": 18.3639300344472, "Respiratory failure": 2.512734333567904, "Second primary malignancy": 125.6648281816963, "Sepsis": 3.5740135215158437, "Septic shock": 4.020458857667626, "Skin lesion": 2.854450858334013, "Spleen disorder": 54.863923691472905, "Splenic infarction": 33.47677254032047, "Splenomegaly": 88.1432121065915, "Squamous cell carcinoma": 60.1541555209201, "Squamous cell carcinoma of skin": 55.94068966087306, "Therapeutic response decreased": 7.238686517410013, "Therapy non-responder": 7.884389993030583, "Therapy partial responder": 22.2700994895276, "Thrombocytopenia": 11.26354219825629, "Thrombocytosis": 30.277601068635413, "Tuberculosis": 10.009631931355113, "Weight increased": 2.353626139839766, "White blood cell count increased": 14.499944644970236, "Withdrawal syndrome": 2.190008556525572}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/976.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/976.json
index b150e86fcf7..a6ccb209cf1 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/976.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/976.json
@@ -1 +1 @@
-{"Abdominal pain ": 2.452993672888997, "Agitation ": 17.25798036615297, "Contraindicated product administered ": 43.16914042468668, "Drug interaction ": 11.202118021478356, "Drug withdrawal syndrome ": 169.31686542854504, "Hyperhidrosis ": 3.3945568991737725, "Tremor ": 5.122760114248426, "Vomiting ": 2.338238382155612, "Withdrawal syndrome ": 146.44392034752178}
\ No newline at end of file
+{"Abdominal discomfort": 4.928615329065679, "Abdominal distension": 6.125049648013135, "Abdominal pain": 3.1270061218339884, "Abdominal pain upper": 5.352729532574385, "Amylase increased": 5.671405673963641, "Blood glucose decreased": 2.5518762333705185, "Blood glucose increased": 5.986417508249924, "Cholecystitis": 7.918149716257222, "Cholelithiasis": 10.993608628219876, "Constipation": 6.813041139702181, "Decreased appetite": 4.630624370270104, "Dehydration": 3.490656515191423, "Diabetes mellitus inadequate control": 7.756962584571959, "Diabetic ketoacidosis": 3.628025515103677, "Diabetic retinopathy": 12.8746826756573, "Diarrhoea": 3.4908555816326894, "Drug intolerance": 2.3860358101300614, "Dysgeusia": 3.8382216287347575, "Dyspepsia": 8.74719335840614, "Eructation": 36.37387142073739, "Feeding disorder": 2.99146242080054, "Flatulence": 12.219614862688434, "Gastritis": 3.3980543583701888, "Gastrointestinal disorder": 5.846777783997132, "Gastrooesophageal reflux disease": 3.5886293668577767, "Glycosylated haemoglobin increased": 24.09881812677861, "Impaired gastric emptying": 31.846828417034583, "Inappropriate schedule of product administration": 3.281266180681732, "Increased appetite": 7.139285735278908, "Intestinal obstruction": 3.58882191137151, "Lipase increased": 8.738680250910418, "Nausea": 4.6055195563627, "Off label use": 3.22520473423637, "Pancreatic carcinoma": 3.8924952381226112, "Pancreatitis": 19.21853285522098, "Pancreatitis acute": 14.240260598248671, "Product taste abnormal": 7.932127145013061, "Surgery": 2.507527795442816, "Taste disorder": 3.242731729133689, "Vomiting": 5.610993235284477, "Weight decreased": 4.488790208661287, "Weight increased": 2.2506990448999686}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/977.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/977.json
index 3e65fd99c41..c3ad02054ed 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/977.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/977.json
@@ -1 +1 @@
-{"Abdominal distension ": 3.803648615338737, "Abnormal dreams ": 13.85767641076035, "Alanine aminotransferase increased ": 3.23207518169336, "Aspartate aminotransferase increased ": 3.69442241785508, "Blood creatine phosphokinase increased ": 5.964969262642309, "Blood iron decreased ": 53.70211449605184, "Cardiac failure congestive ": 3.321421416109072, "Dyspepsia ": 4.174230861818576, "Feeling abnormal ": 3.0819472255478364, "Fluid retention ": 10.271647889462724, "Hyperhidrosis ": 8.677378671384481, "Hypoglycaemia ": 2.0805126115547115, "Hypotension ": 2.5863873547714142, "Loss of consciousness ": 13.864678498138977, "Malaise ": 2.942363592521839, "Muscle spasms ": 13.696256817795092, "Myalgia ": 2.0151036703337253, "Nasopharyngitis ": 3.130926206794654, "Pain in extremity ": 3.958832904283301, "SARS-CoV-2 test positive ": 12.460136442818133, "Sleep disorder ": 23.535549495256504, "Weight decreased ": 2.913650581537416, "Wrong technique in product usage process ": 4.325201595762777}
\ No newline at end of file
+{"Acute myeloid leukaemia": 21.11643262684059, "Acute myeloid leukaemia recurrent": 145.84955215907334, "Cardiac failure": 4.074568562285673, "Cytopenia": 26.640344848081067, "Death": 2.6702350341078445, "Diarrhoea": 2.003861665248529, "Dysphagia": 4.109702489882915, "Electrocardiogram QT prolonged": 7.2936575098600755, "Febrile neutropenia": 11.25544469682487, "Infection": 3.195243809750964, "Malignant neoplasm progression": 3.180868996190057, "Neutropenia": 2.3791614184298058, "Platelet count decreased": 2.519442343503037, "Sepsis": 5.740105490322061, "Thrombocytopenia": 3.353188559199371}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/978.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/978.json
index 63333ecd2e4..c0a84021657 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/978.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/978.json
@@ -1 +1 @@
-{"Blood glucose increased ": 10.244760568773994, "Device defective ": 367.6225842969492, "Device issue ": 208.83513639037133, "Device mechanical issue ": 3579.844043190258, "Lipodystrophy acquired ": 373.8506342293514}
\ No newline at end of file
+{"Alopecia": 8.309080153397142, "Amenorrhoea": 24.40258963306568, "Condition aggravated": 5.51454914662635, "Depressed mood": 7.165686182664994, "Depression": 3.658163558345122, "Heavy menstrual bleeding": 18.50896560490084, "Hot flush": 18.619776393643296, "Intermenstrual bleeding": 25.013564563326437, "Irritability": 6.512210919621305, "Mood swings": 15.989526844285349, "Uterine haemorrhage": 229.40645517067435, "Uterine leiomyoma": 107.13312254126102, "Vaginal haemorrhage": 13.048797638803364, "Weight increased": 6.999568246078738}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/979.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/979.json
index 19014a8861f..5d65175071a 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/979.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/979.json
@@ -1 +1 @@
-{"Anxiety ": 4.85346854084976, "Completed suicide ": 14.871168272252872, "Craniocerebral injury ": 167.3458246406038, "Depression ": 8.940130051093895, "Disturbance in attention ": 5.686928432736939, "Drug ineffective ": 2.160587792198032, "Drug interaction ": 7.201249448703478, "Fall ": 4.886163105432081, "Mental disorder ": 14.850121211582309, "Overdose ": 2.7941216912224616, "Somnolence ": 5.187009858581808, "Suicidal ideation ": 4.669139802160048, "Tension ": 111.91417830769328}
\ No newline at end of file
+{"Alopecia": 9.636692109612964, "Asthenia": 3.4898966546508143, "Constipation": 5.365902569482233, "Diarrhoea": 6.040315265193301, "Disease progression": 7.583682373247642, "Febrile neutropenia": 7.74948614293307, "Inappropriate schedule of product administration": 5.937126614629556, "Nausea": 2.0328100483561284, "Neutropenia": 17.93030147149197, "Weight decreased": 2.3863244987262107, "Weight fluctuation": 118.35994500566149}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/98.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/98.json
index c68f73da44c..0ba35e98513 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/98.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/98.json
@@ -1 +1 @@
-{"Pyrexia ": 2.457279491154506}
\ No newline at end of file
+{"Completed suicide": 93.52661870911469}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/980.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/980.json
index 5a51ee609f6..d8924ac62e6 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/980.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/980.json
@@ -1 +1 @@
-{"Acute disseminated encephalomyelitis ": 4.933298989315599, "Adverse reaction ": 2.345142765917581, "Allodynia ": 5.414745025642478, "Areflexia ": 2.481457877917973, "Bedridden ": 7.999370464617441, "Bell's palsy ": 6.537760825699066, "Blister ": 8.610809653613563, "Burning sensation ": 3.4613820752133324, "Cataract nuclear ": 10.838850829974946, "Cellulitis ": 4.505923853931332, "Coronavirus infection ": 3.585258967277259, "Deafness unilateral ": 2.586832722419568, "Demyelinating polyneuropathy ": 5.473951036233877, "Demyelination ": 2.744088513231518, "Diplegia ": 2.131450858535953, "Disease prodromal stage ": 165.76668080753683, "Dysaesthesia ": 2.8905713208285144, "Encephalitis ": 3.3898367066919715, "Encephalitis viral ": 4.673784061810857, "Erysipelas ": 2.025042717552456, "Erythema ": 3.932258186552604, "Erythema of eyelid ": 2.3120989233592377, "Extensive swelling of vaccinated limb ": 2.789259949399849, "Extra dose administered ": 5.62001279064319, "Eyelid function disorder ": 6.768377804158275, "Facial pain ": 4.525290989994191, "Facial paralysis ": 2.898783531907706, "Facial paresis ": 2.7140209439453, "Genital herpes ": 4.082154682408016, "Genital herpes zoster ": 24.78772370011829, "Genital rash ": 5.188881946145443, "Giant cell arteritis ": 2.9806985227915392, "Groin pain ": 2.608380318746482, "Guillain-Barre syndrome ": 13.135795378956232, "Herpes ophthalmic ": 17.45890440622003, "Herpes simplex ": 8.856628670201761, "Herpes virus infection ": 7.40865426325525, "Herpes zoster ": 40.42503127967853, "Herpes zoster cutaneous disseminated ": 36.22663769366602, "Herpes zoster disseminated ": 10.525816003714905, "Herpes zoster oticus ": 32.34507630398697, "Herpes zoster reactivation ": 26.978841374842805, "Hordeolum ": 3.615883212957467, "Hyperaesthesia ": 10.07633204483132, "Immobile ": 4.709129800598367, "Inappropriate schedule of product administration ": 2.5767991977469977, "Incomplete course of vaccination ": 109.4928881444932, "Incorrect route of product administration ": 4.319765846356616, "Induration ": 6.626357417620879, "Influenza like illness ": 2.436974412323524, "Injected limb mobility decreased ": 10.441437278510396, "Injection site cellulitis ": 6.530320765352262, "Injection site discolouration ": 5.046640069872426, "Injection site discomfort ": 2.602954285544476, "Injection site erythema ": 5.500099841118324, "Injection site induration ": 2.732815818348413, "Injection site pain ": 2.418107481043463, "Injection site paraesthesia ": 3.400698010385687, "Injection site pruritus ": 2.199849579983649, "Injection site rash ": 5.68896327002099, "Injection site swelling ": 3.569833087863631, "Injection site urticaria ": 2.1352605955515496, "Injection site vesicles ": 16.17702748093092, "Injection site warmth ": 2.3752134852848696, "Keratitis ": 2.306277065812683, "Lip blister ": 6.88812791092473, "Local reaction ": 18.19812847694293, "Loss of personal independence in daily activities ": 2.4680461370999, "Lyme disease ": 3.075687566700229, "Lymphangitis ": 4.846824258841722, "Mobility decreased ": 3.374531468335576, "Monoplegia ": 3.3504338913242737, "Myelitis transverse ": 3.615304624341296, "Near death experience ": 2.390199920178497, "Neck pain ": 2.0036743922054576, "Nerve injury ": 3.661290444507724, "Neuralgia ": 10.176061067158184, "Neuralgic amyotrophy ": 5.856573990103475, "Neuritis ": 4.008085739666925, "Nuchal rigidity ": 2.106848332491285, "Occipital neuralgia ": 6.811069586264487, "Ophthalmic herpes simplex ": 24.165679154344176, "Ophthalmic herpes zoster ": 40.93649928081029, "Oral herpes ": 9.725664672497496, "Oral mucosal blistering ": 3.5862812780054707, "Pain ": 3.0336105842129872, "Pain in extremity ": 3.0119131796131686, "Pain of skin ": 7.593015475575824, "Paralysis ": 2.8871048689421164, "Paresis ": 2.0918397076855904, "Peripheral swelling ": 2.3111403842813765, "Peripheral vascular disorder ": 3.63445877473144, "Photophobia ": 2.156099987719906, "Polymyalgia rheumatica ": 5.157116798092937, "Post herpetic neuralgia ": 44.72816960934562, "Product administered at inappropriate site ": 6.27996401683862, "Product administered to patient of inappropriate age ": 19.92911847991682, "Product supply issue ": 9.317305533237832, "Pruritus ": 2.4041225153954917, "Pustule ": 6.682751848251535, "Rash ": 2.785161541227747, "Rash erythematous ": 2.058244239464839, "Rash macular ": 2.0877453918095847, "Rash papular ": 2.750786067681384, "Rash pruritic ": 2.646759493432042, "Rash pustular ": 5.398692419341064, "Rash vesicular ": 37.92686597504371, "Scab ": 5.896810379119218, "Scar ": 4.1891411260517, "Sensitive skin ": 2.130809912542475, "Skin irritation ": 2.087154532336783, "Skin lesion ": 3.7751905352692336, "Skin warm ": 7.371041915438083, "Social problem ": 2.6676622469391456, "Swelling ": 2.4234070669453565, "Tenderness ": 2.323960855289271, "Trigeminal neuralgia ": 4.371691530872508, "Vaccination failure ": 7.83525686928528, "Vaccination site erythema ": 3.121030838091634, "Vaccination site induration ": 2.660334521140563, "Vaccination site inflammation ": 5.729856469302089, "Vaccination site joint swelling ": 4.963823471425084, "Vaccination site oedema ": 2.3788726115111585, "Vaccination site rash ": 2.357277570363777, "Vaccination site reaction ": 2.465968547612385, "Vaccination site swelling ": 2.5347762362199484, "Vaccination site warmth ": 3.654581646572177, "Varicella ": 2.381712401955125, "Varicella zoster virus infection ": 10.863486284427804, "Vestibular neuronitis ": 2.025822824028672, "Walking aid user ": 2.5429212659521205}
\ No newline at end of file
+{"Alanine aminotransferase increased": 3.272590419130843, "Altered state of consciousness": 11.7634952913407, "Aspartate aminotransferase increased": 4.372499876593629, "Blood creatinine increased": 7.059129899999058, "Blood potassium increased": 33.017386769864274, "Blood pressure decreased": 7.826072920779882, "Blood urea increased": 16.712761217307744, "Cardiac failure": 15.72259053907789, "Cardiac failure chronic": 94.06503655237576, "Cardiac failure congestive": 3.5556774532194275, "Cerebral infarction": 24.206126142812487, "Dehydration": 22.65121158237264, "Drug interaction": 2.188201575445348, "Glomerular filtration rate decreased": 10.993233127056232, "Hepatic encephalopathy": 30.619023253576987, "Hepatic function abnormal": 12.598073836728853, "Hyperkalaemia": 19.29091023550353, "Hypernatraemia": 314.1517471146926, "Hypokalaemia": 6.69753829212873, "Hyponatraemia": 6.57251775209672, "Hypotension": 3.744395756199896, "Incorrect dose administered": 3.77453488412448, "Liver disorder": 4.238596509568318, "Multiple organ dysfunction syndrome": 6.9206296233715205, "Oedema peripheral": 3.2546033438959947, "Platelet count decreased": 2.003277381202369, "Pleural effusion": 5.187255704087886, "Product use in unapproved indication": 2.05334191748412, "Rapid correction of hyponatraemia": 5993.302475013472, "Renal failure": 2.63273681633115, "Renal impairment": 22.26499340303588, "Shock": 7.025387275642692, "Thirst": 10.199955214385623}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/981.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/981.json
index 398582c1234..9fbc09c96b4 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/981.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/981.json
@@ -1 +1 @@
-{"Abnormal behaviour ": 5.513847270309444, "Abnormal dreams ": 4.549356890943895, "Aggression ": 5.269033713701167, "Agitation ": 5.282561823073042, "Apathy ": 2.982740107341061, "Behaviour disorder ": 16.669319252473922, "Bipolar disorder ": 14.717135730229309, "Blood creatine phosphokinase increased ": 2.2590907344583733, "Bulimia nervosa ": 236.9393873635864, "Chromaturia ": 2.81198359050999, "Circulatory collapse ": 2.080122945048522, "Cognitive disorder ": 3.0722213782506933, "Compulsive sexual behaviour ": 242.80041011613463, "Compulsive shopping ": 722.4348656547571, "Condition aggravated ": 2.0629572914169625, "Confusional state ": 3.8568550732206095, "Delirium ": 6.279004804662711, "Delusion ": 5.636504886584267, "Dementia ": 3.323804362684906, "Dependence ": 19.03212372873904, "Depression ": 2.206091542051284, "Diplopia ": 4.799839783460544, "Dyskinesia ": 12.306324604090507, "Dystonia ": 5.454671926522068, "Eating disorder ": 6.481126856873063, "Economic problem ": 2.3264920782076506, "Emotional disorder ": 4.114688556790301, "Fall ": 2.589194973438706, "Fear ": 3.7696767035812018, "Food craving ": 28.259577915258152, "Gait disturbance ": 2.173291515652892, "Gambling ": 231.20483300422177, "Gambling disorder ": 821.3678350455043, "Hallucination ": 17.357361828954794, "Hallucination, auditory ": 6.003134274361014, "Hallucination, visual ": 27.067351593524997, "Hepatic steatosis ": 2.793041950447652, "Hyperkinesia ": 57.17855982258489, "Hyperphagia ": 20.000566725393885, "Hypersexuality ": 348.30223798376875, "Impulse-control disorder ": 477.8563340275925, "Insomnia ": 2.737387988726551, "Intestinal obstruction ": 3.372427046127813, "Libido increased ": 68.8112909051405, "Mania ": 5.120873990572349, "Medication error ": 2.637235467890542, "Mental disorder ": 4.908716868074454, "Mental impairment ": 3.1143873074312083, "Motor dysfunction ": 4.883028722099444, "Muscle rigidity ": 4.681903116351543, "Nightmare ": 3.913379328905386, "Nikolsky's sign ": 64.05248677783362, "Obsessive-compulsive disorder ": 20.97054602236829, "Oedema peripheral ": 5.378747567457739, "On and off phenomenon ": 71.00047408638419, "Orthostatic hypotension ": 5.726944059099861, "Overdose ": 2.5762404735889946, "Panic attack ": 2.224470168023422, "Paranoia ": 4.578169682881997, "Parkinson's disease ": 15.664549898185424, "Parkinsonism ": 12.737749659104246, "Personality change ": 11.775302922678398, "Product residue present ": 8.836813178268656, "Psychomotor hyperactivity ": 17.707000380016478, "Psychotic disorder ": 4.195641263478115, "Rash papular ": 3.7677820191499465, "Restless legs syndrome ": 28.826429076411973, "Restlessness ": 3.6987992323590873, "Rhabdomyolysis ": 2.720041660178831, "Road traffic accident ": 4.237886059468402, "Sleep attacks ": 148.7369415378984, "Sleep disorder ": 5.621318224776958, "Somnolence ": 4.6624266050746455, "Stereotypy ": 174.20719820759956, "Stevens-Johnson syndrome ": 2.3956492362203927, "Sudden onset of sleep ": 105.48880376705112, "Suicide attempt ": 6.288174730926103, "Therapeutic product effect decreased ": 3.0787677808053973, "Toxic epidermal necrolysis ": 3.383928282951689, "Tremor ": 2.465815858571809, "Urinary hesitation ": 21.89736590855564, "Weight increased ": 2.83760571523999, "Withdrawal syndrome ": 4.069195062798588}
\ No newline at end of file
+{"Blood lactic acid increased": 300.6426071405326, "Diplopia": 79.86579112512173, "Dysphagia": 25.71960913371485, "Eyelid ptosis": 300.42700844247446, "Lactic acidosis": 30.76625312782692, "Lipodystrophy acquired": 540.0979097647316, "Mitochondrial toxicity": 1873.104789775333, "Ophthalmoplegia": 798.8004375898169}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/982.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/982.json
index 7cbc33500d8..6a6821b232e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/982.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/982.json
@@ -1 +1 @@
-{"Blood glucose increased ": 6.740362856729726, "Diabetes mellitus ": 29.916075994128832, "Diarrhoea ": 2.9543420369916387, "Electrocardiogram QT prolonged ": 7.4799445025262035, "Glycosylated haemoglobin increased ": 27.43364251437124, "Hyperglycaemia ": 46.301680078031445, "Product use in unapproved indication ": 3.3022063131151542, "Weight decreased ": 2.9265723616837835}
\ No newline at end of file
+{"Myelosuppression": 25.945340301620405, "Off label use": 36.22825570857228}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/983.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/983.json
index 9400fb2339c..88903150543 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/983.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/983.json
@@ -1 +1 @@
-{"Acute myocardial infarction ": 5.27425411888543, "Acute respiratory failure ": 2.0849890719467794, "Aortic valve stenosis ": 18.686773899753693, "Ascites ": 2.159338827572346, "Blindness ": 2.77538486915733, "Blindness unilateral ": 2.292071863349082, "Blood potassium decreased ": 3.849831335416373, "Blood pressure abnormal ": 2.812260876014433, "Blood pressure decreased ": 3.196709479030938, "Blood pressure diastolic abnormal ": 17.986525269218156, "Blood pressure diastolic increased ": 8.626600819360837, "Blood pressure systolic abnormal ": 18.298201427140228, "Blood pressure systolic increased ": 2.83232864221768, "Blood urine present ": 2.154138867592138, "Bradycardia ": 3.032438785622027, "Cardiac arrest ": 3.117569094702355, "Cardiac failure ": 3.3668424705518327, "Cardiac failure chronic ": 6.243108876084706, "Cardio-respiratory arrest ": 2.598528224645253, "Cardiogenic shock ": 5.457572158318087, "Cardiomegaly ": 3.838548750865446, "Cardioversion ": 16.144124748598774, "Carotid artery stenosis ": 8.654882544316697, "Circulatory collapse ": 2.361503825826227, "Completed suicide ": 3.952708396662169, "Disease progression ": 2.1215191073545943, "Drug ineffective for unapproved indication ": 2.036832974608958, "Drug interaction ": 2.922029830485636, "Dyschromatopsia ": 23.04524250915977, "Dyspepsia ": 3.1599159678592583, "Dyspnoea exertional ": 4.203366135241993, "Ear infection ": 2.7089588197975654, "Emotional disorder ": 2.3232156438278952, "Erectile dysfunction ": 7.753459628164362, "Erection increased ": 13.849516792828432, "Essential hypertension ": 10.512962713762334, "Exercise tolerance decreased ": 2.0939113016873887, "Eye haemorrhage ": 3.340113090596747, "Fluid retention ": 5.228181747611984, "Flushing ": 5.172087673620214, "Foetal exposure during pregnancy ": 3.8869326701876297, "Foetal growth restriction ": 5.807199561487288, "Haemodynamic instability ": 13.95609906640038, "Haemoperitoneum ": 11.033157092236992, "Haemoptysis ": 3.241616977688742, "Hypervolaemia ": 8.36017983770305, "Hypoacusis ": 2.927163252978739, "Hypotension ": 4.003674522018887, "Hypoxia ": 4.075372613822369, "Implantable defibrillator insertion ": 25.749770746545995, "Intentional product misuse ": 2.088038196609052, "Ischaemic stroke ": 3.8034227662386986, "Left ventricular hypertrophy ": 6.765230377894711, "Left-to-right cardiac shunt ": 391.0388391056505, "Low birth weight baby ": 2.805055652249801, "Maculopathy ": 17.732171691654205, "Malignant melanoma ": 10.874259051185092, "Maternal exposure during pregnancy ": 3.500998077933269, "Myocardial rupture ": 98.62741075263312, "Nasal congestion ": 4.903028496670616, "Oedema ": 4.0061419508836895, "Oedema peripheral ": 2.135272736936991, "Off label use ": 2.3506839054252, "Optic ischaemic neuropathy ": 75.23133853382573, "Ovarian cyst ": 5.196500991959199, "Oxygen saturation decreased ": 5.834543748083668, "Pain in jaw ": 9.434279023778418, "Penile pain ": 16.692366677633938, "Pericardial effusion ": 3.635812119953557, "Premature baby ": 12.684793034210598, "Premature delivery ": 42.25080244367314, "Prescription drug used without a prescription ": 14.7685029771604, "Priapism ": 52.61127406357554, "Product contamination ": 122.30050970217188, "Product counterfeit ": 88.98924937323102, "Product substitution issue ": 3.434213382524677, "Product use issue ": 2.8464683223840743, "Pulmonary arterial hypertension ": 35.90049776212775, "Pulmonary arterial pressure increased ": 50.3140559679749, "Pulmonary hypertension ": 25.67079141601149, "Pulmonary hypertensive crisis ": 154.89982622942753, "Pulmonary oedema ": 5.90920893639601, "Respiratory arrest ": 4.489935694678202, "Respiratory failure ": 2.6569114172657624, "Retinal vein occlusion ": 5.923870450942348, "Right ventricular dysfunction ": 46.27767370872581, "Right ventricular failure ": 34.67934897692163, "Self-medication ": 20.359204309053364, "Stress ": 2.6225849839214184, "Subarachnoid haemorrhage ": 4.296289355427225, "Sudden death ": 3.613650152188775, "Sudden hearing loss ": 7.163089731070371, "Therapy non-responder ": 2.349940471280815, "Toxicity to various agents ": 2.624526114735678, "Transient global amnesia ": 23.6167519778792, "Tricuspid valve incompetence ": 9.719907738195158, "Type V hyperlipidaemia ": 46.70673341204428, "Ventilation perfusion mismatch ": 140.679676670132, "Ventricular tachycardia ": 3.770439724460064, "Vision blurred ": 2.6986618795781907, "Visual acuity reduced ": 3.8887951264231178, "Visual field defect ": 5.638836987703472}
\ No newline at end of file
+{"Acute kidney injury": 4.392615441494683, "Bradycardia": 11.208551563114597, "Hyperkalaemia": 18.61780433466925, "Hypoglycaemia": 13.6410932370172, "Hypotension": 5.806960426412726}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/984.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/984.json
index 1a4a314e5c3..22c3aa247c0 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/984.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/984.json
@@ -1 +1 @@
-{"Anogenital warts ": 347.5575008371184, "Cervical dysplasia ": 309.445057320626, "Loss of consciousness ": 3.173172786041904, "Muscular weakness ": 3.8414880279171935, "Papilloma viral infection ": 421.0598913020565, "Syncope ": 5.987060720644636, "Vertigo ": 6.382726178439767}
\ No newline at end of file
+{"Abdominal distension": 5.957598101981265, "Abdominal pain": 3.4936723303290007, "Abdominal pain upper": 3.821252996149209, "Abortion": 5.70146086621288, "Abortion spontaneous": 2.41651665995451, "Amylase increased": 7.238104714883996, "Appendicitis": 3.4932959877051197, "Appetite disorder": 24.66198093097622, "Autoimmune thyroiditis": 2.2262395950530425, "Bile duct stone": 15.290520358307775, "Biliary colic": 47.086584547086616, "Breath odour": 10.363382417658302, "Cholangitis": 3.1651063863210624, "Cholecystectomy": 29.167290568733552, "Cholecystitis": 33.63457735568049, "Cholecystitis acute": 16.040874763471027, "Cholelithiasis": 49.67993708648, "Colitis": 2.0367498075175074, "Constipation": 7.9996044600362435, "Dehydration": 3.792830754762152, "Depressed mood": 2.299246972206367, "Depression suicidal": 4.852419087068935, "Depressive symptom": 5.487649066973128, "Device defective": 9.49710710207634, "Device delivery system issue": 10.632177693672356, "Device failure": 4.389112637582569, "Device issue": 3.0876532440296365, "Device malfunction": 5.053351282439603, "Device mechanical issue": 31.536713402270976, "Diarrhoea": 3.076528977029254, "Diarrhoea haemorrhagic": 3.903181212810469, "Disability": 3.019790070550251, "Diverticulitis": 3.9104814756767343, "Drug delivery system issue": 10.475156925010918, "Drug diversion": 7.625587751494669, "Drug dose titration not performed": 77.11765511333691, "Drug effect less than expected": 13.47457734922356, "Drug titration error": 38.86317134855557, "Dry mouth": 2.6159183987498835, "Dyspepsia": 8.065031145930122, "Early satiety": 15.180222425405, "Eructation": 46.19149517450522, "Flatulence": 9.188334633323032, "Food aversion": 9.9954406755654, "Food craving": 67.90899668149329, "Food intolerance": 3.9593160360086697, "Food poisoning": 7.74825804228397, "Gallbladder disorder": 8.285145149548281, "Gallbladder operation": 17.142103989999185, "Gastritis": 8.102702654106327, "Gastroenteritis": 4.977572882944337, "Gastrointestinal necrosis": 5.953425285382934, "Gastrooesophageal reflux disease": 4.842495478386171, "Heart rate increased": 2.044610068856188, "Hepatic steatosis": 3.3003074561353016, "Hiccups": 3.8060620152388194, "Hip surgery": 5.885408695448563, "Hunger": 37.143218299659054, "Hyperchlorhydria": 9.95746035965688, "Hypoglycaemic unconsciousness": 3.59117805970665, "Illness": 2.102160483761197, "Impaired gastric emptying": 9.82577811679446, "Inappropriate schedule of product administration": 3.6130814909044062, "Incorrect dose administered by device": 8.670079993897534, "Increased appetite": 14.291121642029738, "Injection site bruising": 17.658288170524308, "Injection site discolouration": 28.08518741703107, "Injection site discomfort": 2.469739815846446, "Injection site erythema": 9.519961246906144, "Injection site haematoma": 2.968113775830008, "Injection site hypersensitivity": 80.45829811070433, "Injection site induration": 5.970067784471712, "Injection site irritation": 48.73667426736208, "Injection site mass": 11.623357067156014, "Injection site oedema": 2.100802002346716, "Injection site pruritus": 19.901706532493257, "Injection site rash": 48.78521392180695, "Injection site reaction": 2.829861355947425, "Injection site swelling": 2.678936252607946, "Injection site urticaria": 45.60513135873133, "Injection site vesicles": 9.071992541974394, "Intentional dose omission": 3.6304570118362287, "Intestinal obstruction": 2.91422178720769, "Intracranial pressure increased": 2.4364285471812592, "Lack of satiety": 362.8339976282431, "Lipase increased": 15.057639001971657, "Liquid product physical issue": 9.349475343780858, "Liver function test increased": 2.0251056417235325, "Nausea": 3.633249372409791, "Nephrolithiasis": 2.6419277717654777, "Obstructive pancreatitis": 26.32632903703612, "Oedematous pancreatitis": 15.68004635983038, "Pancreatic carcinoma": 2.896273958730941, "Pancreatic carcinoma metastatic": 2.9478176547389245, "Pancreatic cyst": 13.737458709428653, "Pancreatic disorder": 7.133313633904936, "Pancreatitis": 27.253388124166133, "Pancreatitis acute": 11.630526219325995, "Pancreatitis necrotising": 11.273877099815111, "Papillary thyroid cancer": 22.8405449442475, "Prescription drug used without a prescription": 10.492383405543332, "Product communication issue": 12.65069974537242, "Product odour abnormal": 4.758113216793893, "Product quality issue": 5.8477870037826944, "Product storage error": 2.6071750114245624, "Regurgitation": 5.1606517877427525, "Renal colic": 5.149954318320227, "Self-injurious ideation": 5.762730828408215, "Skin odour abnormal": 6.3898460015954255, "Skin reaction": 2.556655108922498, "Small intestinal obstruction": 2.6217734919539297, "Suicidal ideation": 3.968819433549519, "Surgery": 4.884745912418875, "Suspected counterfeit product": 10.071801270447484, "Thyroid cancer": 10.415305713153726, "Thyroid mass": 18.97454354213747, "Vomiting": 4.034071050675505, "Weight increased": 3.925125353851069, "Weight loss poor": 965.4894508152456, "Wrong technique in product usage process": 3.17691861269496, "Yellow skin": 2.0406543872942104}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/985.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/985.json
index b2b1f7a5c4c..ee200c2a47d 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/985.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/985.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.272005504017268, "Aspartate aminotransferase increased ": 5.423597768572754, "Drug interaction ": 3.230265018571265, "Ejaculation disorder ": 429.8428525703207, "Ejaculation failure ": 286.1101086178015, "Hepatic function abnormal ": 8.72391390976674, "Loss of consciousness ": 8.387300798338616, "Orthostatic hypotension ": 29.59600039660548, "Prostate cancer ": 37.36992534930331, "Retrograde ejaculation ": 777.6218048306735, "Syncope ": 6.065066819576177, "Urinary retention ": 10.201231061991292}
\ No newline at end of file
+{"Cardiac failure": 4.535385738744379, "Disease progression": 4.406367710131015, "Electrocardiogram QT prolonged": 10.286915074612551, "Lipase increased": 47.84433307375701, "Neutropenia": 3.8962484749966126, "Off label use": 2.0143490537423747, "Pancreatitis": 11.790948559960835, "Pancytopenia": 10.519882618710938, "Platelet count decreased": 8.565671453799533, "Thrombocytopenia": 13.528911315760654, "White blood cell count decreased": 3.248883719516391}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/986.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/986.json
index 954b4248c7e..20d298f9b8b 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/986.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/986.json
@@ -1 +1 @@
-{"Dizziness ": 2.793465152464892, "Ejaculation disorder ": 137.4318489637387, "Ejaculation failure ": 726.424772227731, "Erectile dysfunction ": 35.6252305452816, "Fall ": 2.411651125548482, "Hypotension ": 2.4335698850660203, "Nasal congestion ": 27.12149106958791, "Orthostatic hypotension ": 25.114345544340733, "Pollakiuria ": 14.650789830120049, "Retrograde ejaculation ": 2112.8729472760488, "Syncope ": 2.8974743140765757}
\ No newline at end of file
+{"Anxiety": 2.7059062670482086, "Asthma": 14.51042168383211, "Chest discomfort": 7.563446633012874, "Chronic obstructive pulmonary disease": 11.00004518009037, "Cough": 4.19809268360293, "Cyanosis": 17.00310165471342, "Depression": 2.6814969961020743, "Dyspnoea": 2.839368963158516, "Dyspnoea exertional": 14.482065994242468, "Emphysema": 44.10726862854626, "Fall": 2.5882369292973846, "Gait disturbance": 2.6080818896957707, "Hiatus hernia": 39.99138034595639, "Hypoaesthesia": 3.45494405934379, "Infection": 5.994181775268377, "Insomnia": 2.8428971111175256, "Overdose": 5.28533097805287, "Pneumonia": 4.802134285370815, "Wheezing": 8.824067007485317}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/987.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/987.json
index b5cb4e52e64..9e26dfeeb6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/987.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/987.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 2.885063112311953, "Ascites ": 7.538686831364737, "Aspartate aminotransferase increased ": 2.9123573867681998, "Blood bilirubin increased ": 14.569413886960778, "Blood creatinine increased ": 3.510474653105271, "Death ": 2.070935707180888, "Drug hypersensitivity ": 2.618375889150215, "Drug ineffective ": 8.257394206336315, "Drug interaction ": 6.683616115460725, "Hepatic failure ": 7.729320461372979, "Hepatic function abnormal ": 2.908375892489848, "Hepatitis B reactivation ": 51.36221335161509, "Hepatitis C ": 234.90436308015376, "Hyperbilirubinaemia ": 37.07307716573468, "Jaundice ": 6.590644487737361, "Off label use ": 11.207440750257168, "Pancreatitis acute ": 7.570739143679191, "Photosensitivity reaction ": 23.011967925880302, "Product use issue ": 14.839077771030553, "Remission not achieved ": 615.722476591015, "Sinus bradycardia ": 25.700989384498843, "Treatment failure ": 20.24657257766281}
\ No newline at end of file
+{}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/988.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/988.json
index 16e4716aa5e..0dc5d9ec12f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/988.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/988.json
@@ -1 +1 @@
-{"Abdominal abscess ": 2.7112756746622257, "Abnormal loss of weight ": 2.036153686104346, "Abscess ": 6.352695421455475, "Abscess limb ": 6.587175574871973, "Abscess oral ": 8.94645775188156, "Accident ": 3.2820869986107435, "Accidental exposure to product ": 35.56048966732856, "Accidental underdose ": 3.5629666945834844, "Adenocarcinoma of colon ": 4.228186817157243, "Administration site bruise ": 12.788536084676805, "Administration site infection ": 394.952495009093, "Adverse drug reaction ": 2.106367527193627, "Adverse event ": 2.8201674592908885, "Alopecia areata ": 2.3484359775252983, "Amyotrophic lateral sclerosis ": 2.794034625955135, "Anal abscess ": 4.164419390009536, "Anal fistula ": 5.600153393094922, "Ankylosing spondylitis ": 53.92058959189155, "Application site discolouration ": 4.7684549251202935, "Application site haemorrhage ": 11.48800511085608, "Arthritis ": 5.314071309640637, "Arthritis bacterial ": 9.194166207051572, "Arthritis infective ": 7.442900895142266, "Arthropod bite ": 4.816677640187761, "Atypical mycobacterial infection ": 9.346436989640852, "Atypical pneumonia ": 2.091746329783416, "Axial spondyloarthritis ": 19.80655651709543, "B-cell lymphoma ": 3.271917969989118, "Basal cell carcinoma ": 3.695839058412672, "Bedridden ": 3.3786508074515447, "Blood test abnormal ": 3.847122215484749, "Body height decreased ": 2.603707816295383, "Breast cancer ": 2.466156238789519, "Bronchitis ": 3.1610697821388025, "Calculus urinary ": 2.5672126505802253, "Cardiac operation ": 2.567181683262328, "Carpal tunnel syndrome ": 3.76397920449278, "Cataract ": 2.623494442773684, "Catarrh ": 3.1217104386428955, "Cellulitis ": 5.348614674958203, "Cervix carcinoma ": 2.780282032043905, "Chemotherapy ": 8.179157021167258, "Chikungunya virus infection ": 24.44434226161309, "Cholecystectomy ": 2.8835840144335765, "Chondropathy ": 6.805798739410735, "Chronic lymphocytic leukaemia ": 2.020569528580177, "Clear cell renal cell carcinoma ": 4.927176858598783, "Colectomy ": 11.0886010197495, "Colitis ulcerative ": 23.74081199370929, "Colon cancer ": 3.3494678636869915, "Complication associated with device ": 7.707073526799235, "Contraindication to vaccination ": 18.77306757272398, "Coronavirus infection ": 5.761598915612019, "Crohn's disease ": 4.203744622114032, "Cutaneous T-cell lymphoma ": 3.8953830292173888, "Cutaneous vasculitis ": 4.111009394232265, "Cyst ": 2.8751909269896183, "Cystitis ": 2.1310052076576023, "Decreased immune responsiveness ": 7.978786524003997, "Demyelinating polyneuropathy ": 3.41203970916565, "Demyelination ": 19.00197816287733, "Dengue fever ": 37.67464378196184, "Dental care ": 29.95925010173976, "Dental operation ": 20.72078576147901, "Dermatitis psoriasiform ": 12.330791412920032, "Device defective ": 15.696902678609572, "Device delivery system issue ": 2.192446137846548, "Device deployment issue ": 225.2386166312527, "Device failure ": 4.065330366951514, "Device infusion issue ": 6.021818327273017, "Device issue ": 17.471085411079095, "Device leakage ": 17.067892173026088, "Device malfunction ": 11.015274183869888, "Device occlusion ": 4.425855776541801, "Device related infection ": 3.253362844794878, "Device use issue ": 6.145832038581172, "Diarrhoea haemorrhagic ": 3.983034612617074, "Disseminated tuberculosis ": 16.766880983805308, "Diverticulitis ": 3.937419107502691, "Drug delivery system issue ": 9.260663263915555, "Drug delivery system malfunction ": 287.3404709635233, "Drug ineffective ": 2.6154554702124213, "Ear infection ": 8.891630658650651, "Emphysema ": 2.100264673101695, "Endocarditis ": 2.315555676713017, "Endodontic procedure ": 9.265416104906818, "Enthesopathy ": 3.2537134148488844, "Eosinophilic pneumonia ": 2.091358311208169, "Erysipelas ": 5.110595521457879, "Exostosis ": 3.627208068385102, "Exposure via skin contact ": 8.904465749708338, "Eye infection ": 7.017748078676494, "Eye operation ": 7.688583849117959, "Faecal calprotectin increased ": 4.653970476897955, "Felty's syndrome ": 72.97621337365652, "Femur fracture ": 2.976877091375123, "Finger deformity ": 2.0552890286926617, "Fistula ": 3.3460958039257145, "Flavivirus infection ": 203.7543551350103, "Food poisoning ": 3.563595338019672, "Foot deformity ": 3.223295380032265, "Foot operation ": 18.31577312161928, "Frequent bowel movements ": 2.156486340711426, "Furuncle ": 5.276529313312872, "Gallbladder operation ": 12.637379452889215, "Gastric infection ": 4.3585492620818185, "Gastrointestinal carcinoma ": 2.1312442902470017, "Gastrointestinal infection ": 3.47225670197126, "Gastrointestinal inflammation ": 2.1777499055544225, "General physical condition abnormal ": 4.184310520707913, "Genital herpes ": 2.145007993156504, "Gingival abscess ": 14.53263905577743, "Gingivitis ": 2.525716439120905, "Glomerulonephritis ": 4.575109649725683, "Glomerulonephritis rapidly progressive ": 6.484344762149149, "Groin abscess ": 9.834170372315082, "Heart valve replacement ": 9.263428047470663, "Hepatitis B ": 2.785829428961921, "Hernia ": 5.859566134299216, "Herpes virus infection ": 6.508781222857118, "Hip arthroplasty ": 7.95387826420482, "Hip surgery ": 11.080690849612647, "Histoplasmosis ": 10.36365976381764, "Hodgkin's disease ": 4.143735488941171, "Hospitalisation ": 3.212112323620605, "Hypersensitivity vasculitis ": 2.642288719273737, "Hysterectomy ": 5.393138011817516, "IgA nephropathy ": 5.703988591736264, "Illness ": 2.1424557833085958, "Immune system disorder ": 2.821191192428743, "Inappropriate schedule of product administration ": 9.3386349855681, "Incorrect dose administered ": 3.3989102635379957, "Infected skin ulcer ": 11.389845601479012, "Infection ": 8.20750251453754, "Infectious mononucleosis ": 2.3080218059244104, "Infectious pleural effusion ": 7.1526169819697145, "Inflammation ": 2.1807749665547336, "Inflammatory bowel disease ": 2.4327272292744544, "Influenza ": 3.658129551757393, "Ingrowing nail ": 4.876522769649607, "Injection related reaction ": 2.143739096956063, "Injection site bruising ": 3.449766689459083, "Injection site extravasation ": 2.0683739426887, "Injection site haemorrhage ": 12.93160701166396, "Injection site hypoaesthesia ": 2.6203940550544287, "Injury associated with device ": 21.941792102594867, "Intervertebral disc operation ": 14.72022707437045, "Intervertebral disc protrusion ": 4.112048057089912, "Intestinal operation ": 22.16145748536113, "Intestinal resection ": 3.927637104681093, "Intraductal proliferative breast lesion ": 4.660898297822259, "Invasive ductal breast carcinoma ": 2.896643699582359, "Iridocyclitis ": 4.692585693953031, "Iritis ": 3.844948164872117, "Joint arthroplasty ": 15.044982719827551, "Joint dislocation ": 2.961737509164242, "Joint effusion ": 2.78675618818426, "Joint lock ": 3.547812834321786, "Joint surgery ": 22.57062903151303, "Joint swelling ": 2.242319374163817, "Juvenile idiopathic arthritis ": 5.119132332524507, "Kidney infection ": 5.884316091920942, "Knee arthroplasty ": 11.68139631167842, "Knee operation ": 18.93369338510496, "Labyrinthitis ": 3.1570523568812368, "Laryngitis ": 2.31615460552948, "Latent tuberculosis ": 9.905819472136274, "Ligament rupture ": 2.7655278369001755, "Ligament sprain ": 2.2760218882182754, "Limb mass ": 7.881293011568928, "Limb operation ": 23.25870233215681, "Localised infection ": 7.508136202735399, "Loss of therapeutic response ": 19.745426658500097, "Lower limb fracture ": 3.4999703139694964, "Lower respiratory tract infection ": 31.340362958976165, "Lung adenocarcinoma ": 6.318837031042986, "Lung neoplasm malignant ": 2.170709280523144, "Lupus nephritis ": 7.734788400795993, "Lupus-like syndrome ": 12.78058568188752, "Lyme disease ": 2.1293046444539776, "Lymph node tuberculosis ": 19.511815467239437, "Lymphocytosis ": 3.1898214192986534, "Lymphoma ": 4.334434223123927, "Lymphoproliferative disorder ": 5.8974497851605765, "Malignant melanoma ": 4.127388079783122, "Marasmus ": 7.252200203772163, "Mass ": 2.8254636166684803, "Medical device implantation ": 12.894906770410708, "Melanocytic naevus ": 5.80786831435327, "Meniscus injury ": 3.197942813221633, "Metabolic surgery ": 9.661356747326696, "Mucous stools ": 3.0455893958702296, "Multiple sclerosis ": 4.120764921466942, "Mycobacterium tuberculosis complex test positive ": 17.61127486185552, "Myelitis ": 2.9197213969571445, "Nasopharyngitis ": 6.057701915236309, "Neck mass ": 3.1235783360129656, "Neck surgery ": 6.978428468167049, "Needle issue ": 30.787679840954063, "Neoplasm ": 4.087961818509343, "Neoplasm malignant ": 2.251512043305429, "Nephrolithiasis ": 2.5735826667052235, "Nerve compression ": 2.410458561107661, "Off label use ": 3.410387744116109, "Optic neuritis ": 2.936252398692796, "Oral fungal infection ": 2.3414551151931, "Oral herpes ": 3.464327395712661, "Oral infection ": 7.165432470939846, "Organising pneumonia ": 3.6307687913081903, "Osteitis ": 5.141914925284588, "Osteoarthritis ": 2.9188609494900883, "Osteomyelitis ": 5.52061225692662, "Ovarian cancer ": 2.204509909589928, "Ovarian cyst ": 2.248867030538873, "Palmoplantar pustulosis ": 43.74717196032708, "Papillary thyroid cancer ": 4.140200018149041, "Papilloma viral infection ": 4.7816475224493775, "Paradoxical drug reaction ": 4.528254006373663, "Paternal exposure during pregnancy ": 13.403767429590582, "Periodontitis ": 3.2935843976316392, "Peritoneal tuberculosis ": 41.63369215343048, "Pharyngitis ": 13.136003645350218, "Pleurisy ": 3.828720880812159, "Pneumocystis jirovecii pneumonia ": 7.1081865439948215, "Pneumonia ": 3.399901393480308, "Pneumonia bacterial ": 5.376148546687255, "Pneumonia legionella ": 8.583554706470188, "Polyarthritis ": 2.793992191043352, "Poor quality product administered ": 6.066648723042844, "Post procedural complication ": 2.14598878252412, "Post procedural infection ": 12.204378354764938, "Postoperative wound infection ": 3.95207084057368, "Product availability issue ": 3.240605375659636, "Product dose omission issue ": 26.76571544098468, "Product label issue ": 5.478927097540825, "Product leakage ": 4.412322200448869, "Product packaging issue ": 5.042618412150207, "Product packaging quantity issue ": 5.663599511864924, "Product quality issue ": 3.685320170090673, "Product storage error ": 10.434149359929174, "Product temperature excursion issue ": 15.615022045150988, "Product use issue ": 4.083128065649463, "Prostate cancer ": 2.0653169739433515, "Psoriasis ": 8.804527773910243, "Psoriatic arthropathy ": 16.789623502663087, "Pulmonary sarcoidosis ": 8.979997762353072, "Pulmonary tuberculosis ": 20.26155849850413, "Pustular psoriasis ": 17.75636317132952, "Pyelonephritis ": 4.778816399039005, "Pyelonephritis acute ": 2.8273420175051323, "Pyoderma gangrenosum ": 6.170425806881032, "Rectal cancer ": 3.151996934427093, "Red blood cell sedimentation rate increased ": 2.2641024436007475, "Respiratory tract infection ": 4.77211241465386, "Respiratory tract infection viral ": 4.627088503696209, "Rheumatic disorder ": 5.415924955997225, "Rheumatoid arthritis ": 11.598284237768317, "Rheumatoid factor increased ": 11.118534032085968, "Rheumatoid vasculitis ": 69.44604739646384, "Rhinitis ": 2.637103055920506, "Sacroiliitis ": 4.213360950886609, "Sarcoidosis ": 5.997387746254527, "Scleritis ": 7.208102999170163, "Seasonal allergy ": 2.26122216087789, "Sepsis ": 2.069441839997049, "Serum ferritin decreased ": 3.480895365711731, "Shoulder arthroplasty ": 7.881198650214441, "Shoulder operation ": 14.517138607867851, "Sinusitis ": 3.250511931828776, "Sjogren's syndrome ": 3.96807228992891, "Skin cancer ": 4.784476622906233, "Skin fissures ": 2.0465736403951573, "Skin infection ": 6.178335242931534, "Skin ulcer ": 2.0077642042958206, "Spinal compression fracture ": 3.0605558675745503, "Spinal disorder ": 3.1933330024430013, "Spinal fracture ": 2.869207135299807, "Spinal operation ": 8.220899970821801, "Spinal pain ": 2.0865054384186266, "Spondylitis ": 12.143500630473383, "Staphylococcal infection ": 2.1336418583935104, "Subcutaneous abscess ": 5.856406556078571, "Surgery ": 16.494767354827935, "Synovial cyst ": 3.7724115050502194, "Syphilis ": 8.450840284203936, "Syringe issue ": 22.95396747525637, "Testis cancer ": 2.285778282492445, "Therapeutic product effect decreased ": 4.001942600489635, "Therapeutic product ineffective ": 4.697098877278535, "Therapeutic response decreased ": 5.767405318091572, "Therapeutic response shortened ": 2.664166430069389, "Therapy cessation ": 3.210780958326456, "Thyroid cancer ": 2.628129881169558, "Toe operation ": 22.811019738467746, "Tonsillitis ": 12.527533604682697, "Tooth abscess ": 14.533739033871369, "Tooth extraction ": 14.075450098102824, "Tooth infection ": 11.580897009012087, "Trigger finger ": 3.368776672478468, "Tuberculin test positive ": 8.516111873440064, "Tuberculosis ": 12.666576930664176, "Tuberculous pleurisy ": 36.96545125535838, "Tympanic membrane perforation ": 5.2546695047423215, "Underdose ": 12.771435580432549, "Upper limb fracture ": 3.054501344071998, "Urinary tract infection ": 5.258487340557847, "Urinary tract infection bacterial ": 3.542583019937372, "Urticarial vasculitis ": 4.790339986845033, "Uterine cancer ": 3.0253010516988272, "Uterine leiomyoma ": 4.046053176215624, "Uveitis ": 8.098305670883718, "Vaginal infection ": 3.3530464162927425, "Varicose vein ": 3.5660068925513744, "Vasculitis ": 2.288891015870034, "Viral infection ": 8.309281132716972, "Volvulus ": 5.013179863358996, "Weight fluctuation ": 2.008695320535374, "Wisdom teeth removal ": 25.204321894204767, "Wound complication ": 4.269209330935535, "Wound infection ": 2.473830686870849, "Wrist surgery ": 13.54534382099552}
\ No newline at end of file
+{"Abdominal pain": 2.452993672888997, "Agitation": 17.25798036615297, "Contraindicated product administered": 43.16914042468668, "Drug interaction": 11.202118021478356, "Drug withdrawal syndrome": 169.31686542854504, "Hyperhidrosis": 3.3945568991737725, "Tremor": 5.122566615646435, "Vomiting": 2.338206840839707, "Withdrawal syndrome": 146.44392034752178}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/989.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/989.json
index 5569b8bc4ec..d87ab5d9780 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/989.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/989.json
@@ -1 +1 @@
-{"Blood creatinine increased ": 10.554728842142492, "Kidney transplant rejection ": 453.1409148085539}
\ No newline at end of file
+{"Abdominal distension": 3.803648615338737, "Abnormal dreams": 13.85767641076035, "Alanine aminotransferase increased": 3.23207518169336, "Aspartate aminotransferase increased": 3.69442241785508, "Blood creatine phosphokinase increased": 5.964969262642309, "Blood iron decreased": 53.70211449605184, "Cardiac failure congestive": 3.321170269965369, "Dyspepsia": 4.174230861818576, "Feeling abnormal": 3.081887905929257, "Fluid retention": 10.271647889462724, "Hyperhidrosis": 8.677378671384481, "Hypoglycaemia": 2.080442388671336, "Hypotension": 2.586327561871762, "Loss of consciousness": 13.863999490917385, "Malaise": 2.9423260221742096, "Muscle spasms": 13.696256817795092, "Myalgia": 2.0151036703337253, "Nasopharyngitis": 3.130687669414229, "Pain in extremity": 3.958811965796304, "SARS-CoV-2 test positive": 12.460136442818133, "Sleep disorder": 23.535549495256504, "Weight decreased": 2.913650581537416, "Wrong technique in product usage process": 4.325201595762777}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/99.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/99.json
index d5cd5aa7e09..27a685379aa 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/99.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/99.json
@@ -1 +1 @@
-{"Accidental overdose ": 2.167754391955064, "Adverse reaction ": 2.880010058198766, "Altered state of consciousness ": 2.325831338877234, "Anti-insulin antibody increased ": 59.33583015662892, "Anti-insulin antibody positive ": 85.92377329816652, "Arterial occlusive disease ": 7.868104115259915, "Bladder disorder ": 2.336487484794882, "Blindness ": 2.9446450514647147, "Blindness unilateral ": 6.007833031212383, "Blood glucose abnormal ": 31.09160162049538, "Blood glucose decreased ": 23.342584118340607, "Blood glucose fluctuation ": 35.05051604653073, "Blood glucose increased ": 22.68102677647207, "Blood immunoglobulin E increased ": 2.705869704756, "Blood testosterone decreased ": 4.174941701338904, "Body mass index decreased ": 19.291730549696872, "Breast mass ": 2.942529427564948, "Cardiac operation ": 2.707884562497488, "Cataract ": 5.567179224070009, "Cataract operation ": 4.741317706965829, "Cataract subcapsular ": 27.86075734754604, "Circumstance or information capable of leading to medication error ": 4.3416142873570704, "Cold sweat ": 6.389651502926942, "Coronary artery bypass ": 2.067180869317517, "Cystoid macular oedema ": 18.28054947007877, "Decreased insulin requirement ": 86.5598897231919, "Dengue fever ": 7.023262360475538, "Device breakage ": 10.872104828391423, "Device defective ": 10.500894062131238, "Device delivery system issue ": 10.14842775513015, "Device failure ": 2.672783589001094, "Device issue ": 25.297186875418888, "Device leakage ": 6.973198821459808, "Device malfunction ": 5.668482407997738, "Device operational issue ": 149.2685631211664, "Device use issue ": 9.380587072768376, "Diabetes mellitus inadequate control ": 35.97878951050089, "Diabetic coma ": 16.647019762471544, "Diabetic hyperglycaemic coma ": 14.604165075366192, "Diabetic ketoacidosis ": 10.414905369798202, "Diabetic metabolic decompensation ": 34.54838936392488, "Diabetic neuropathy ": 9.022097189309632, "Diabetic retinal oedema ": 74.65499416522792, "Diabetic retinopathy ": 25.62535292506332, "Disability ": 4.110727697261855, "Drug dose omission by device ": 5.867757818378583, "Drug ineffective ": 2.0242300473953865, "Episcleritis ": 20.25263306984255, "Expired device used ": 22.927041270887827, "Expired product administered ": 14.903526541911017, "Exposure during pregnancy ": 3.5266191998398755, "Exposure via breast milk ": 4.679806767191686, "Extra dose administered ": 7.200250256029633, "Eye disorder ": 2.0224992256868477, "Eye haemorrhage ": 4.1376915037159385, "Feeding disorder ": 2.200481598379397, "Foetal death ": 2.6517066733453296, "Foetal exposure timing unspecified ": 31.996543563908563, "Foot fracture ": 2.231357501520031, "Glaucoma ": 2.369939819928134, "Glycosylated haemoglobin increased ": 18.337459709271396, "Haemodialysis ": 4.399460559223785, "Hospitalisation ": 2.695624824094257, "Hunger ": 10.082621613127468, "Hyperglycaemia ": 46.0319744874429, "Hyperhidrosis ": 2.609194761429089, "Hyperinsulinaemic hypoglycaemia ": 69.5945885267812, "Hyperphagia ": 6.448577327692834, "Hypoglycaemia ": 42.34131185817496, "Hypoglycaemia neonatal ": 6.384772064162495, "Hypoglycaemia unawareness ": 12.24910543048068, "Hypoglycaemic coma ": 26.75085237494848, "Hypoglycaemic encephalopathy ": 26.810776635127752, "Hypoglycaemic seizure ": 30.74112026948308, "Hypoglycaemic unconsciousness ": 36.21847582303528, "Incorrect dose administered ": 5.788217640698246, "Incorrect dose administered by device ": 18.20653141122177, "Induration ": 2.9074057633998875, "Infarction ": 2.5236176431260184, "Injection site abscess ": 5.370000190017354, "Injection site atrophy ": 10.28397994628966, "Injection site bruising ": 6.9708808808052725, "Injection site discolouration ": 15.114670136864794, "Injection site haematoma ": 2.073989742540092, "Injection site haemorrhage ": 9.32127309417551, "Injection site hypersensitivity ": 16.83129912904313, "Injection site induration ": 2.7167980293634484, "Injection site infection ": 5.354479576643265, "Injection site injury ": 12.294740008179598, "Injection site mass ": 2.4272433607256487, "Injection site nodule ": 7.265806005051203, "Injection site oedema ": 3.33371711902046, "Injection site urticaria ": 4.612655303432383, "Insulin resistance ": 9.37935011209292, "Intentional product misuse ": 2.351465915269948, "Intestinal haemorrhage ": 3.23129869500408, "Ketoacidosis ": 11.672285212230252, "Ketonuria ": 9.11514108200945, "Ketosis ": 10.538052985742596, "Kidney infection ": 2.0473225956662087, "Leg amputation ": 4.660726542374589, "Limb operation ": 5.10137353160867, "Lipoatrophy ": 7.125962489516124, "Lipodystrophy acquired ": 16.60002005215803, "Liquid product physical issue ": 7.7358756873391075, "Localised infection ": 3.8379834481655744, "Loss of consciousness ": 3.9167986581702574, "Macular degeneration ": 2.0058052895522818, "Macular oedema ": 8.016697006377177, "Maternal exposure timing unspecified ": 2.697791923505208, "Medication error ": 7.345847296120676, "Multiple lentigines syndrome ": 366.7779925124033, "Multiple use of single-use product ": 118.0375707069236, "Near death experience ": 3.485166423720468, "Nervousness ": 4.356519650079207, "Pancreatic carcinoma metastatic ": 2.781309411080744, "Pancreatic disorder ": 7.440167161696918, "Polydipsia ": 4.6502909501666005, "Poor quality product administered ": 4.811088468265711, "Postprandial hypoglycaemia ": 21.529138873615903, "Premature baby ": 2.436063399738545, "Product administration error ": 5.531902959028437, "Product complaint ": 8.971059113318463, "Product dispensing error ": 2.1700914004896266, "Product odour abnormal ": 4.190460787440595, "Product physical consistency issue ": 7.495901403956943, "Product prescribing error ": 2.753771634500222, "Product quality issue ": 7.321487308441586, "Product storage error ": 22.440878059765357, "Product use issue ": 3.203746619264044, "Reaction to excipient ": 3.455825536814637, "Renal disorder ": 2.498579569981992, "Renal transplant ": 4.630432785192785, "Retinal detachment ": 2.7577817439844647, "Retinal haemorrhage ": 3.028669202061544, "Retinopathy ": 8.404037389713883, "Road traffic accident ": 2.490099813857005, "Shock hypoglycaemic ": 20.10688559038641, "Sopor ": 16.184612484409396, "Substance use ": 12.853629370532426, "Tendon disorder ": 2.7638024226646825, "Therapeutic product effect delayed ": 6.61364248628943, "Therapeutic response decreased ": 2.578719328131786, "Thermal burn ": 4.782710996071542, "Thirst ": 3.5401881717143766, "Tinea infection ": 28.121610736862504, "Tinea pedis ": 16.430660482397638, "Toe amputation ": 7.771512294073851, "Type I hypersensitivity ": 3.5320080350561143, "Type III immune complex mediated reaction ": 47.4973388468732, "Type IV hypersensitivity reaction ": 2.6959263537112155, "Unevaluable event ": 2.7757365196115167, "Urine ketone body present ": 14.101791098860597, "Vision blurred ": 2.571685654584165, "Visual impairment ": 4.656397479508501, "Weight increased ": 3.0033977762618456, "Wheelchair user ": 6.771274412636358, "Wrong product administered ": 72.10811377078747, "Wrong technique in device usage process ": 7.34919612818718, "Wrong technique in product usage process ": 2.1722458020917}
\ No newline at end of file
+{"Blister": 50.60769786611604, "Conjunctivitis": 236.7319672946979, "Genital erosion": 7210.221152950711, "Lip erosion": 2995.653479617848, "Nikolsky's sign": 3068.614566788939, "Oral mucosa erosion": 1806.993202921764, "Pruritus": 9.15608401822802, "Pyrexia": 2.4837242761356952, "Rash papular": 167.107402485623, "Toxic epidermal necrolysis": 162.71917378687976}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/990.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/990.json
index 83c2b9e32ba..547d7ad02fc 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/990.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/990.json
@@ -1 +1 @@
-{"Acute kidney injury ": 3.534002050770199, "Angioedema ": 7.539282653142957, "Drug ineffective for unapproved indication ": 20.73629511858232, "Drug interaction ": 16.028467435603925, "Liver transplant rejection ": 340.61135450972023, "Off label use ": 3.729097752444501, "Product use in unapproved indication ": 8.569177872753905, "Transplant rejection ": 68.93462089310147}
\ No newline at end of file
+{"Blood glucose increased": 10.244760568773994, "Device defective": 367.6225842969492, "Device issue": 208.83513639037133, "Device mechanical issue": 3579.844043190258, "Lipodystrophy acquired": 373.8506342293514}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/991.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/991.json
index e90d93e216f..30d8e15d661 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/991.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/991.json
@@ -1 +1 @@
-{"Alanine aminotransferase increased ": 4.805884049268032, "Anaemia ": 3.8919569772032, "Aspartate aminotransferase increased ": 4.228994240474632, "Blood potassium decreased ": 18.92882110415466, "Death ": 2.4279047452921247, "Drug-induced liver injury ": 11.673509466573538, "Electrocardiogram QT prolonged ": 112.0765038457217, "Haemoglobin decreased ": 2.7795116537951228, "Hepatic function abnormal ": 4.097208895425196, "Hypokalaemia ": 3.030467415493918, "Intentional product use issue ": 20.168822450481315, "Liver injury ": 12.052242875590746, "Neuropathy peripheral ": 7.838234172403804, "Off label use ": 5.954712686280971, "Product use issue ": 5.170778410045484, "Pulmonary tuberculosis ": 70.57367086101097, "Rash pruritic ": 3.546455720479756, "Respiratory failure ": 11.785268074799006}
\ No newline at end of file
+{"Anxiety": 4.85346854084976, "Completed suicide": 14.871168272252872, "Craniocerebral injury": 167.3458246406038, "Depression": 8.940130051093895, "Disturbance in attention": 5.686928432736939, "Drug ineffective": 2.160571820819458, "Drug interaction": 7.201249448703478, "Fall": 4.886037850581472, "Mental disorder": 14.850121211582309, "Overdose": 2.7941216912224616, "Somnolence": 5.1869526787453015, "Suicidal ideation": 4.669139802160048, "Tension": 111.91417830769328}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/992.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/992.json
index 5556a4777ca..3adc4c58392 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/992.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/992.json
@@ -1 +1 @@
-{"Acute kidney injury ": 2.587392476279438, "Angioedema ": 3.835539714065976, "Atrial fibrillation ": 3.154185122295811, "Blood glucose increased ": 2.143764055540013, "Completed suicide ": 19.66567288460777, "Diabetes mellitus ": 7.759073765927343, "Diabetes mellitus inadequate control ": 24.894974495762845, "Drug interaction ": 3.1260122672941804, "Hyperkalaemia ": 6.01427606706304, "Hypoglycaemia ": 13.790223559575583, "Infusion site extravasation ": 175.88972800076286, "Lactic acidosis ": 21.52830886033204, "Loss of consciousness ": 2.3883140827112337, "Pemphigoid ": 36.49822139696445, "Product monitoring error ": 290.8439585151044, "Toxicity to various agents ": 5.338830471858231, "Tremor ": 2.0420897356310355, "Wrong patient received product ": 94.19399297381086}
\ No newline at end of file
+{"Acute disseminated encephalomyelitis": 4.930235841435739, "Adverse reaction": 2.343686588602761, "Allodynia": 5.411382948831568, "Areflexia": 2.4799171088027743, "Bedridden": 7.994403003829035, "Bell's palsy": 6.533700957413349, "Blister": 8.605461266346376, "Burning sensation": 3.459232501789458, "Cataract nuclear": 10.832120897159616, "Cellulitis": 4.503125644263784, "Coronavirus infection": 3.583032788599771, "Deafness unilateral": 2.585226494230535, "Demyelinating polyneuropathy": 5.470552204905991, "Demyelination": 2.742384673431669, "Diplegia": 2.130127421609234, "Disease prodromal stage": 165.6637547237272, "Dysaesthesia": 2.888776473596866, "Encephalitis": 3.387731826277921, "Encephalitis viral": 4.670882081830588, "Erysipelas": 2.023785332942559, "Erythema": 3.929776690717176, "Erythema of eyelid": 2.310663327175245, "Extensive swelling of vaccinated limb": 2.7875279290666524, "Extra dose administered": 5.616523038220247, "Eyelid function disorder": 6.7641752795963805, "Facial pain": 4.522481011114067, "Facial paralysis": 2.89698346642293, "Facial paresis": 2.712335720163058, "Genital herpes": 4.079620006066168, "Genital herpes zoster": 24.772332819476965, "Genital rash": 5.185660131362184, "Giant cell arteritis": 2.978847776514664, "Groin pain": 2.6067607063008253, "Guillain-Barre syndrome": 13.12763770515259, "Herpes ophthalmic": 17.44806349894638, "Herpes simplex": 8.85112909970152, "Herpes virus infection": 7.404053840389325, "Herpes zoster": 40.42696419966883, "Herpes zoster cutaneous disseminated": 36.20414392049136, "Herpes zoster disseminated": 10.519280370414725, "Herpes zoster oticus": 32.324991656953955, "Herpes zoster reactivation": 26.962089273872877, "Hordeolum": 3.613638084200257, "Hyperaesthesia": 10.070074794262313, "Immobile": 4.70620578673606, "Inappropriate schedule of product administration": 2.593977331095404, "Incomplete course of vaccination": 109.4248946274265, "Incorrect route of product administration": 4.31708336266103, "Induration": 6.622242883776575, "Influenza like illness": 2.435460804149605, "Injected limb mobility decreased": 10.43495345706578, "Injection site cellulitis": 6.526266015407827, "Injection site discolouration": 5.043506502453442, "Injection site discomfort": 2.6013380600099656, "Injection site erythema": 5.504619205490667, "Injection site induration": 2.7311188812816414, "Injection site pain": 2.416574929186505, "Injection site paraesthesia": 3.3985864868480173, "Injection site pruritus": 2.198483517006423, "Injection site rash": 5.685430685795132, "Injection site swelling": 3.575588906173622, "Injection site urticaria": 2.133934774743472, "Injection site vesicles": 16.166982609354992, "Injection site warmth": 2.373738445696642, "Keratitis": 2.304845081029533, "Lip blister": 6.883850925151239, "Local reaction": 18.186827113880906, "Loss of personal independence in daily activities": 2.466513469593412, "Lyme disease": 3.0737778449555964, "Lymphangitis": 4.843814823203149, "Mobility decreased": 3.3724358327000568, "Monoplegia": 3.3483534982745744, "Myelitis transverse": 3.613059822671248, "Near death experience": 2.3887158031154905, "Neck pain": 2.002430105797637, "Nerve injury": 3.6590169976077367, "Neuralgia": 10.169741013643447, "Neuralgic amyotrophy": 5.852937535851595, "Neuritis": 4.00559703262613, "Nuchal rigidity": 2.1055401776083964, "Occipital neuralgia": 6.806840554150423, "Ophthalmic herpes simplex": 24.1506742503519, "Ophthalmic herpes zoster": 40.91107645972315, "Oral herpes": 9.719624967156149, "Oral mucosal blistering": 3.584054439747989, "Pain": 3.0333930249001373, "Pain in extremity": 3.0121266454667994, "Pain of skin": 7.587280494387752, "Paralysis": 2.8853121020806904, "Paresis": 2.0905408548852527, "Peripheral swelling": 2.30970501345412, "Peripheral vascular disorder": 3.632201996482195, "Photophobia": 2.1545617429604995, "Polymyalgia rheumatica": 5.153914517344019, "Post herpetic neuralgia": 44.700391768942254, "Product administered at inappropriate site": 6.276064580275574, "Product administered to patient of inappropriate age": 19.91674250024481, "Product supply issue": 9.311520051021926, "Pruritus": 2.404985996847171, "Pustule": 6.67860217576878, "Rash": 2.7852110400387518, "Rash erythematous": 2.056966086328629, "Rash macular": 2.086448974167201, "Rash papular": 2.748772098288438, "Rash pruritic": 2.6451158311213683, "Rash pustular": 5.395340133803078, "Rash vesicular": 37.9863897226526, "Scab": 5.891218744659309, "Scar": 4.186539917986181, "Sensitive skin": 2.1294868268329803, "Skin irritation": 2.085858564606795, "Skin lesion": 3.7728462365479913, "Skin warm": 7.366464822355538, "Social problem": 2.666005857915874, "Swelling": 2.4219020221210203, "Tenderness": 2.322517785795833, "Trigeminal neuralgia": 4.3689770098445, "Vaccination failure": 7.835836030644842, "Vaccination site erythema": 3.1190925999891164, "Vaccination site induration": 2.6586826396203564, "Vaccination site inflammation": 5.726298444507652, "Vaccination site joint swelling": 4.960741404371193, "Vaccination site oedema": 2.377395474010266, "Vaccination site rash": 2.355813867948944, "Vaccination site reaction": 2.4642977727690805, "Vaccination site swelling": 2.533202111257863, "Vaccination site warmth": 3.652312274873157, "Varicella": 2.380233506327491, "Varicella zoster virus infection": 10.856740810180936, "Vestibular neuronitis": 2.024564978362966, "Walking aid user": 2.541342339980898}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/993.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/993.json
index d48ba8dbfd2..3f6b5aa769e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/993.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/993.json
@@ -1 +1 @@
-{"Completed suicide ": 102.5292937671624, "Intentional product misuse ": 101.95006512172726, "Toxicity to various agents ": 89.14388211807089}
\ No newline at end of file
+{"Abnormal behaviour": 5.513847270309444, "Abnormal dreams": 4.549356890943895, "Aggression": 5.269033713701167, "Agitation": 5.282561823073042, "Apathy": 2.982740107341061, "Behaviour disorder": 16.669319252473922, "Bipolar disorder": 14.717135730229309, "Blood creatine phosphokinase increased": 2.2590907344583733, "Bulimia nervosa": 236.9393873635864, "Chromaturia": 2.81198359050999, "Circulatory collapse": 2.080122945048522, "Cognitive disorder": 3.0722213782506933, "Compulsive sexual behaviour": 242.80041011613463, "Compulsive shopping": 722.4348656547571, "Condition aggravated": 2.0629572914169625, "Confusional state": 3.8568550732206095, "Delirium": 6.279004804662711, "Delusion": 5.636504886584267, "Dementia": 3.323804362684906, "Dependence": 19.03212372873904, "Depression": 2.206091542051284, "Diplopia": 4.799839783460544, "Dyskinesia": 12.306324604090507, "Dystonia": 5.454671926522068, "Eating disorder": 6.481126856873063, "Economic problem": 2.3264920782076506, "Emotional disorder": 4.114688556790301, "Fall": 2.589128559482718, "Fear": 3.7696767035812018, "Food craving": 28.259577915258152, "Gait disturbance": 2.173252098490064, "Gambling": 231.20483300422177, "Gambling disorder": 821.3678350455043, "Hallucination": 17.357361828954794, "Hallucination, auditory": 6.003134274361014, "Hallucination, visual": 27.067351593524997, "Hepatic steatosis": 2.793041950447652, "Hyperkinesia": 57.07474492455968, "Hyperphagia": 20.000566725393885, "Hypersexuality": 348.30223798376875, "Impulse-control disorder": 477.8563340275925, "Insomnia": 2.737387988726551, "Intestinal obstruction": 3.372427046127813, "Libido increased": 68.8112909051405, "Mania": 5.120873990572349, "Medication error": 2.6370461751022813, "Mental disorder": 4.908716868074454, "Mental impairment": 3.1143873074312083, "Motor dysfunction": 4.883028722099444, "Muscle rigidity": 4.681903116351543, "Nightmare": 3.913379328905386, "Nikolsky's sign": 64.05248677783362, "Obsessive-compulsive disorder": 20.97054602236829, "Oedema peripheral": 5.378614452202058, "On and off phenomenon": 71.00047408638419, "Orthostatic hypotension": 5.725709897526539, "Overdose": 2.5762404735889946, "Panic attack": 2.224470168023422, "Paranoia": 4.578169682881997, "Parkinson's disease": 15.664549898185424, "Parkinsonism": 12.737749659104246, "Personality change": 11.775302922678398, "Product residue present": 8.836813178268656, "Psychomotor hyperactivity": 17.703927955028576, "Psychotic disorder": 4.195641263478115, "Rash papular": 3.76736545593414, "Restless legs syndrome": 28.826429076411973, "Restlessness": 3.698603996491606, "Rhabdomyolysis": 2.720041660178831, "Road traffic accident": 4.237886059468402, "Sleep attacks": 148.13713456773235, "Sleep disorder": 5.621318224776958, "Somnolence": 4.66237514501855, "Stereotypy": 174.20719820759956, "Stevens-Johnson syndrome": 2.3956492362203927, "Sudden onset of sleep": 105.48880376705112, "Suicide attempt": 6.288174730926103, "Therapeutic product effect decreased": 3.0787677808053973, "Toxic epidermal necrolysis": 3.383928282951689, "Tremor": 2.4657226615544543, "Urinary hesitation": 21.89736590855564, "Weight increased": 2.83760571523999, "Withdrawal syndrome": 4.069195062798588}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/994.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/994.json
index 98425854fcf..bd5af026074 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/994.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/994.json
@@ -1 +1 @@
-{"Abortion spontaneous ": 2.6603026197685966, "Acne ": 2.9781726311055223, "Arthritis ": 2.6599646368819707, "Breast cancer ": 2.2396290525552947, "Breast cancer female ": 20.32500959336669, "C-reactive protein increased ": 2.1839893856036063, "Crohn's disease ": 4.50837570888682, "Dermatitis exfoliative generalised ": 7.194891813052414, "Device issue ": 13.560675352538166, "Eczema ": 4.736086608017973, "Fungal infection ": 4.248896072883334, "Hepatic cirrhosis ": 5.032679332844837, "Infection ": 2.076296230291741, "Injection site haemorrhage ": 7.501150440632723, "Intestinal obstruction ": 4.3577606665814885, "Lung neoplasm malignant ": 3.0857363616944395, "Lymphoma ": 9.202427564839976, "Maternal exposure during pregnancy ": 2.287321105344685, "Prostate cancer ": 4.411043624079024, "Psoriasis ": 52.788970015310994, "Psoriatic arthropathy ": 11.436602027411512, "Skin disorder ": 2.893564877162633, "Skin exfoliation ": 4.724383334782908, "Skin lesion ": 3.2214622849295544, "Skin plaque ": 19.38948657278382, "Stress ": 2.8421787837467627, "Surgery ": 3.857534673620018, "Therapeutic product effect decreased ": 3.301838321950351, "Therapeutic product effect incomplete ": 2.7402657450757384, "Therapeutic response shortened ": 65.13614588318256, "Tuberculosis ": 6.927601925234758, "Unevaluable event ": 14.657310260828504}
\ No newline at end of file
+{"Blood glucose increased": 6.740362856729726, "Diabetes mellitus": 29.916075994128832, "Diarrhoea": 2.95431738112365, "Electrocardiogram QT prolonged": 7.4799445025262035, "Glycosylated haemoglobin increased": 27.43364251437124, "Hyperglycaemia": 46.301680078031445, "Product use in unapproved indication": 3.3021033407076965, "Weight decreased": 2.9265723616837835}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/995.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/995.json
index ffcf99a6793..19da4aedc6e 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/995.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/995.json
@@ -1 +1 @@
-{"Aggression ": 75.87874501894635, "Agitation ": 33.4324342605909, "Irritability ": 30.747741661972785, "Middle insomnia ": 108.16237748116951, "Product administered to patient of inappropriate age ": 129.40971429495238, "Somnolence ": 3.3420522460603426}
\ No newline at end of file
+{"Acute myocardial infarction": 5.27220839707501, "Acute respiratory failure": 2.084180572034294, "Aortic valve stenosis": 18.67952779479054, "Ascites": 2.1585014095108868, "Blindness": 2.7743084691538504, "Blindness unilateral": 2.2911830730152403, "Blood potassium decreased": 3.848338323989801, "Blood pressure abnormal": 2.811170325509885, "Blood pressure decreased": 3.195365582724019, "Blood pressure diastolic abnormal": 17.979550696670326, "Blood pressure diastolic increased": 8.623255708745148, "Blood pressure systolic abnormal": 18.291105997256984, "Blood pressure systolic increased": 2.83123030975194, "Blood urine present": 2.153303563139485, "Bradycardia": 3.031167349040817, "Cardiac arrest": 3.116359758503636, "Cardiac failure": 3.365228706711856, "Cardiac failure chronic": 6.240687948742012, "Cardio-respiratory arrest": 2.59752040279868, "Cardiogenic shock": 5.4554555801865385, "Cardiomegaly": 3.837060207415077, "Cardioversion": 16.13786459601993, "Carotid artery stenosis": 8.651526466993742, "Circulatory collapse": 2.360588013235098, "Completed suicide": 3.9511749090980097, "Disease progression": 2.120696189668473, "Drug ineffective for unapproved indication": 2.0360431227650664, "Drug interaction": 2.944051131307243, "Dyschromatopsia": 23.03630613635852, "Dyspepsia": 3.158690222655019, "Dyspnoea exertional": 4.201735777816239, "Ear infection": 2.70790835033851, "Emotional disorder": 2.322314766399705, "Erectile dysfunction": 7.750452183301921, "Erection increased": 13.844145622627291, "Essential hypertension": 10.50888608751662, "Exercise tolerance decreased": 2.0930993515053293, "Eye haemorrhage": 3.3388178219758973, "Fluid retention": 5.226153907556587, "Flushing": 5.170081286603288, "Foetal exposure during pregnancy": 3.8854247751640623, "Foetal growth restriction": 5.804947577549806, "Haemodynamic instability": 13.950686601811007, "Haemoperitoneum": 11.028878799817454, "Haemoptysis": 3.2403597907396637, "Hypervolaemia": 8.356937713996084, "Hypoacusis": 2.92578156339221, "Hypotension": 4.002028008797963, "Hypoxia": 4.073791967406138, "Implantable defibrillator insertion": 25.739785855873027, "Intentional product misuse": 2.0872283339887896, "Ischaemic stroke": 3.8019477407911904, "Left ventricular hypertrophy": 6.762607013923545, "Left-to-right cardiac shunt": 390.88721284453896, "Low birth weight baby": 2.8039679309322456, "Maculopathy": 17.725295668340177, "Malignant melanoma": 10.870041311769825, "Maternal exposure during pregnancy": 3.4996399373896203, "Myocardial rupture": 98.5891662373671, "Nasal congestion": 4.901126740203188, "Oedema": 4.004587913951187, "Oedema peripheral": 2.1343916733515877, "Off label use": 2.3496788671827726, "Optic ischaemic neuropathy": 75.20215636705277, "Ovarian cyst": 5.194485959881008, "Oxygen saturation decreased": 5.8319674707231846, "Pain in jaw": 9.43061971669005, "Penile pain": 16.685893859860872, "Pericardial effusion": 3.634402074554965, "Premature baby": 12.679871868393905, "Premature delivery": 42.23440861178727, "Prescription drug used without a prescription": 14.762775935472376, "Priapism": 52.59086758151312, "Product contamination": 122.25307621397302, "Product counterfeit": 88.95473527871532, "Product substitution issue": 3.4328815420474204, "Product use issue": 2.845364128056071, "Pulmonary arterial hypertension": 35.886569843965944, "Pulmonary arterial pressure increased": 50.29454400773064, "Pulmonary hypertension": 25.660831726918104, "Pulmonary hypertensive crisis": 154.8397607935615, "Pulmonary oedema": 5.906138990817183, "Respiratory arrest": 4.4881942808425785, "Respiratory failure": 2.6556613471057844, "Retinal vein occlusion": 5.921573342203902, "Right ventricular dysfunction": 46.2597280487371, "Right ventricular failure": 34.66589698568978, "Self-medication": 20.351309600838626, "Stress": 2.6215678972586574, "Subarachnoid haemorrhage": 4.294623274069011, "Sudden death": 3.612248808174224, "Sudden hearing loss": 7.160311971399755, "Therapy non-responder": 2.348823763325063, "Toxicity to various agents": 2.6235078789012847, "Transient global amnesia": 23.607594090671142, "Tricuspid valve incompetence": 9.716138405049865, "Type V hyperlipidaemia": 46.688622161568986, "Ventilation perfusion mismatch": 140.62512651391532, "Ventricular tachycardia": 3.768977490333261, "Vision blurred": 2.6976150027680004, "Visual acuity reduced": 3.8872870043724688, "Visual field defect": 5.63665021492165}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/996.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/996.json
index a5e3117581e..5fbd282f18c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/996.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/996.json
@@ -1 +1 @@
-{"Ammonia increased ": 85.14768935177429, "Cardiac arrest ": 5.691845298571863, "Cerebrovascular insufficiency ": 1687.92266617122, "Cluster headache ": 93.0829645908044, "Coma ": 7.077070081568211, "Confusional state ": 4.934083684780522, "Drug abuse ": 8.448666755634182, "Drug interaction ": 14.412439204413706, "Drug level increased ": 21.253946300848245, "Electroencephalogram abnormal ": 87.68644476337025, "Eye movement disorder ": 46.17764180242136, "Inhibitory drug interaction ": 199.73286981245587, "Miosis ": 51.29912456556964, "Multiple organ dysfunction syndrome ": 10.636908014887943, "Myoclonus ": 24.15322610955697, "Overdose ": 17.66334240346588, "Somnolence ": 3.1921552910163924, "Toxicity to various agents ": 19.5116998130631}
\ No newline at end of file
+{"Anogenital warts": 347.5575008371184, "Cervical dysplasia": 309.445057320626, "Loss of consciousness": 3.1730175039864505, "Muscular weakness": 3.8414880279171935, "Papilloma viral infection": 421.0598913020565, "Syncope": 5.98697831457964, "Vertigo": 6.382726178439767}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/997.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/997.json
index b7579aa727f..edb0cada43c 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/997.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/997.json
@@ -1 +1 @@
-{"Anaemia ": 2.415525757893432, "Ascites ": 5.870984986841708, "Bradycardia ": 8.356652730122704, "Death ": 2.2323323476761026, "Drug ineffective ": 5.700443190181129, "Drug interaction ": 4.796295965875079, "Genotype drug resistance test positive ": 117.6370637123594, "Hepatitis C ": 72.37544742557667, "Hepatocellular carcinoma ": 23.772727215694548, "Intentional dose omission ": 99.27973837023455, "Product dose omission issue ": 6.241568586349409, "Treatment failure ": 27.035609476735512}
\ No newline at end of file
+{"Acute kidney injury": 2.272005504017268, "Aspartate aminotransferase increased": 5.423597768572754, "Drug interaction": 3.230265018571265, "Ejaculation disorder": 429.8428525703207, "Ejaculation failure": 286.1101086178015, "Hepatic function abnormal": 8.72391390976674, "Loss of consciousness": 8.386890293191739, "Orthostatic hypotension": 29.58962732444576, "Prostate cancer": 37.36992534930331, "Retrograde ejaculation": 777.6218048306735, "Syncope": 6.064983345005123, "Urinary retention": 10.201231061991292}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/998.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/998.json
index 30aefc3432f..c6852691c9f 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/998.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/998.json
@@ -1 +1 @@
-{"Acute graft versus host disease ": 2.478358234942793, "Acute leukaemia ": 5.949533547804612, "Acute myeloid leukaemia ": 2.276415224685003, "Acute pulmonary oedema ": 2.366473995716444, "Adenovirus infection ": 3.1555051019269347, "Anaemia ": 2.565039342901669, "Antiphospholipid syndrome ": 6.005879457919846, "Anuria ": 5.166221789558011, "Aplastic anaemia ": 25.90175120911438, "Ascites ": 2.3419238942317158, "Aspergillus infection ": 3.883642484979247, "Atypical haemolytic uraemic syndrome ": 216.3983531703212, "Azotaemia ": 2.5321653911045474, "BK virus infection ": 6.9306087829626986, "Bacteraemia ": 11.145804522172426, "Bacterial infection ": 2.1304357343552662, "Bacterial sepsis ": 6.543925587176647, "Bilirubin conjugated increased ": 3.088625228958405, "Biopsy bone marrow ": 46.76781484618534, "Blood albumin decreased ": 3.505038087470169, "Blood alkaline phosphatase decreased ": 14.841952018907833, "Blood bilirubin abnormal ": 12.210732089417172, "Blood bilirubin increased ": 3.417550672733784, "Blood calcium decreased ": 3.1813955358978463, "Blood creatinine abnormal ": 15.802140752682744, "Blood creatinine decreased ": 5.051875513251869, "Blood creatinine increased ": 4.373496698708891, "Blood immunoglobulin G decreased ": 10.986152632239996, "Blood iron increased ": 10.427783985467917, "Blood lactate dehydrogenase abnormal ": 101.34597063900117, "Blood lactate dehydrogenase decreased ": 56.00349057592518, "Blood lactate dehydrogenase increased ": 35.60085408299439, "Blood phosphorus increased ": 3.863269243143953, "Blood product transfusion dependent ": 118.76351582461368, "Blood urea abnormal ": 11.157115973904633, "Blood urea increased ": 3.470609917540145, "Blood urine present ": 4.958396586578211, "Bone marrow disorder ": 3.3744199824965198, "Bone marrow failure ": 7.500506749184425, "Bone marrow transplant ": 23.455756218133427, "Brain death ": 4.301777384748771, "Brain herniation ": 3.4196445622305407, "Brain oedema ": 2.6145675610783314, "Breakthrough haemolysis ": 1446.759529463025, "Bronchopulmonary aspergillosis ": 2.0081406932870385, "Budd-Chiari syndrome ": 72.96835794595576, "C3 glomerulopathy ": 223.8140278735098, "Catheter site infection ": 9.41449924980452, "Catheter site pain ": 5.938609232789995, "Cellulitis ": 2.540578644706549, "Cerebral ischaemia ": 2.4499518259595185, "Cerebral thrombosis ": 2.8560551110615293, "Cholangitis ": 2.1464272869291823, "Cholecystitis ": 4.317567596492592, "Cholecystitis acute ": 2.0962157568382405, "Cholelithiasis ": 6.01150075147884, "Chromaturia ": 13.05094762921445, "Clostridium difficile colitis ": 2.129515562404018, "Clostridium difficile infection ": 3.514460961807502, "Complement factor C3 decreased ": 116.21100592287922, "Complement factor C4 decreased ": 40.69589737779844, "Complement factor abnormal ": 399.2111708483052, "Complement factor decreased ": 46.76781484618534, "Complement factor increased ": 93.0389962069208, "Complications of transplanted kidney ": 8.122790420817836, "Condition aggravated ": 3.835520609419027, "Congenital aplasia ": 3.287029783163081, "Coombs direct test positive ": 13.336696194738334, "Coombs test positive ": 36.323655983216646, "Critical illness ": 24.64823357335205, "Cytomegalovirus infection ": 2.962784070128101, "Cytomegalovirus viraemia ": 4.228851188833217, "Device related infection ": 18.38374204773497, "Device related sepsis ": 10.222546515519932, "Dialysis ": 9.089613092822114, "Disease complication ": 6.438250251137331, "Disease recurrence ": 4.0509259955231744, "Drug level below therapeutic ": 3.1295819537836214, "End stage renal disease ": 6.830664147567471, "Endocarditis ": 5.17153649138042, "Enterococcal infection ": 6.992351349020736, "Enterococcal sepsis ": 20.70417650545461, "Epstein-Barr viraemia ": 10.655160517689186, "Escherichia bacteraemia ": 7.350693579725144, "Escherichia infection ": 3.5555367976179983, "Escherichia sepsis ": 9.700010020606848, "Escherichia test positive ": 19.20546884435191, "Escherichia urinary tract infection ": 12.798199854839448, "Exposure during pregnancy ": 4.95084432075327, "Exposure via breast milk ": 2.737814209660672, "Extravascular haemolysis ": 1919.7828075689256, "Eyelid ptosis ": 2.8590461622136334, "Foetal death ": 2.0097005830904786, "Foetal distress syndrome ": 3.5202506094449846, "Foetal growth restriction ": 2.2726505064272544, "Gallbladder disorder ": 2.304502041323132, "Gastroenteritis ": 2.526082567188653, "Gastroenteritis viral ": 4.5738984238466704, "Gastrointestinal infection ": 3.210488869710817, "Gene mutation ": 18.92707525505111, "Glomerular filtration rate decreased ": 2.4117230144325097, "Glomerulonephritis ": 4.517016546393328, "Glomerulonephritis membranoproliferative ": 30.24916690227435, "Glomerulosclerosis ": 14.076968450905982, "Graft loss ": 50.3872008445028, "Graft versus host disease ": 9.755736146155233, "Graft versus host disease in gastrointestinal tract ": 3.332435899124008, "Haematocrit abnormal ": 22.55126218028763, "Haematocrit decreased ": 10.356739423965822, "Haematology test abnormal ": 36.99931267664951, "Haematuria ": 2.580322675520116, "Haemodialysis ": 5.917146356762338, "Haemoglobin abnormal ": 23.84354479832607, "Haemoglobin decreased ": 16.205545224929168, "Haemoglobinuria ": 371.4056217042755, "Haemolysis ": 192.81031087555183, "Haemolytic anaemia ": 5.002499370960031, "Haemolytic uraemic syndrome ": 58.054788372196384, "Haptoglobin abnormal ": 420.6650807916568, "Haptoglobin decreased ": 149.76344178660727, "Haptoglobin increased ": 96.85133304387536, "Hepatic vein thrombosis ": 30.239663279417364, "Hepatomegaly ": 2.0192498845453515, "Hospitalisation ": 7.735863960498301, "Hypervolaemia ": 7.358756562480629, "Immunosuppression ": 6.524575619371689, "Inappropriate schedule of product administration ": 6.142843112685863, "Incorrect dose administered ": 8.97936764452443, "Infection ": 4.402589324630535, "International normalised ratio decreased ": 2.1764887078622754, "Intestinal perforation ": 3.808176551217093, "Intravascular haemolysis ": 97.73568906188568, "Iron binding capacity total decreased ": 64.26689007438506, "Iron overload ": 32.60414501583814, "Jaundice ": 2.718728821578664, "Kidney fibrosis ": 11.370703177887169, "Kidney transplant rejection ": 14.985101057727126, "Klebsiella infection ": 7.068295718307272, "Laboratory test abnormal ": 13.700520684656396, "Low birth weight baby ": 2.0953899761895527, "Malignant hypertension ": 23.650686245210693, "Maternal exposure during breast feeding ": 2.504567731024204, "Mean cell volume increased ": 11.107163247770677, "Meningitis ": 6.487533766053176, "Meningitis meningococcal ": 111.5718939991666, "Meningococcal bacteraemia ": 207.8043086040115, "Meningococcal infection ": 242.7543101087164, "Meningococcal sepsis ": 335.3369801704848, "Microangiopathic haemolytic anaemia ": 10.146375979739236, "Microangiopathy ": 9.029373011729698, "Multimorbidity ": 34.63443148832581, "Multiple organ dysfunction syndrome ": 5.58569698589678, "Myasthenia gravis ": 43.35999711736493, "Myasthenia gravis crisis ": 157.05129187414656, "Myelodysplastic syndrome ": 9.82888400172119, "Necrotising fasciitis ": 3.525176853769997, "Neurological decompensation ": 6.687708171394188, "Neuromyelitis optica spectrum disorder ": 43.3034429151255, "Neutrophil count increased ": 2.2969193170329643, "Ocular icterus ": 3.6767950684675497, "Off label use ": 3.978882006778616, "Oliguria ": 2.401780381679244, "Pancytopenia ": 2.0656798948700525, "Paroxysmal nocturnal haemoglobinuria ": 341.02619745721444, "Pericardial effusion ": 2.042029565695339, "Peritonitis ": 3.420306724646078, "Peritonitis bacterial ": 7.502961139070839, "Plasmapheresis ": 44.02007672414733, "Platelet count abnormal ": 21.21316660301365, "Platelet count decreased ": 6.19643322816443, "Platelet count increased ": 3.206291831953534, "Platelet transfusion ": 10.450685731660364, "Pneumonia ": 2.137274505992892, "Pneumonia fungal ": 2.917763809911303, "Pneumonia klebsiella ": 8.790475350240348, "Poor venous access ": 47.56172966933303, "Portal hypertension ": 4.200131786818342, "Portal vein thrombosis ": 5.939272258552816, "Post procedural haemorrhage ": 4.40645166568044, "Posterior reversible encephalopathy syndrome ": 2.6519255309959227, "Postoperative wound infection ": 2.703345824660892, "Pre-eclampsia ": 7.7935883153693934, "Pregnancy ": 6.053885613760671, "Premature baby ": 2.6549410145049994, "Premature delivery ": 2.4634929034490574, "Procalcitonin increased ": 7.3629327914664335, "Protein urine present ": 2.159528002687648, "Proteinuria ": 6.018766268441128, "Pseudomonal sepsis ": 12.840627580830272, "Pseudomonas infection ": 6.825609567625249, "Pulmonary haemorrhage ": 6.182812603604899, "Pulmonary oedema ": 2.0590294775563405, "Pyelonephritis ": 2.1887411300806843, "Red blood cell count decreased ": 3.365340548700763, "Red blood cell schistocytes present ": 57.98788632389085, "Red blood cell transfusion ": 24.26143917712872, "Red cell distribution width increased ": 4.156781438887766, "Renal impairment ": 4.042232743342304, "Renal transplant ": 18.44691073834847, "Renal transplant failure ": 46.31826733669602, "Renal tubular necrosis ": 2.4225284528929056, "Respiratory failure ": 2.4692892217199107, "Respiratory tract infection ": 4.528831017994116, "Respiratory tract infection viral ": 6.825116666609919, "Reticulocyte count increased ": 112.93651513627036, "Reticulocytosis ": 45.13466966658407, "SARS-CoV-2 test positive ": 4.838366183420367, "Scleroderma ": 4.50555135793533, "Sepsis ": 5.153488382121923, "Septic shock ": 6.13758482147272, "Serum ferritin increased ": 9.984120278895205, "Splenomegaly ": 3.8200350769207656, "Staphylococcal bacteraemia ": 5.9768115884475455, "Staphylococcal infection ": 4.152381685386734, "Staphylococcal sepsis ": 10.176987260901477, "Suspected COVID-19 ": 8.466035033613304, "Symptom recurrence ": 8.449623123579581, "Terminal state ": 2.657530068205909, "Therapeutic response shortened ": 4.101116030953178, "Thrombosis ": 2.2037143568700666, "Thrombotic microangiopathy ": 55.79067919032297, "Thrombotic thrombocytopenic purpura ": 3.3535379076915657, "Total complement activity decreased ": 1002.0522991421444, "Total complement activity increased ": 1159.028160661451, "Transfusion ": 16.60125081570065, "Transfusion reaction ": 20.802075077006705, "Transplant dysfunction ": 9.890275038463871, "Transplant failure ": 16.061658812125795, "Transplant rejection ": 24.032326702736743, "Treatment noncompliance ": 2.0433348947919527, "Unevaluable event ": 3.083328262944219, "Upper respiratory tract infection ": 4.291966417716509, "Urinary tract infection ": 3.318577053368496, "Urine output decreased ": 2.367064845381979, "Urosepsis ": 2.560234902103685, "Uterine leiomyoma ": 2.7909059933957154, "Vascular device infection ": 6.553491076826704, "Viral infection ": 8.17613756144806, "Viral upper respiratory tract infection ": 6.560302115070571, "White blood cell count abnormal ": 2.6088109657321885}
\ No newline at end of file
+{"Dizziness": 2.7934457592605537, "Ejaculation disorder": 137.4318489637387, "Ejaculation failure": 726.424772227731, "Erectile dysfunction": 35.6252305452816, "Fall": 2.411589310745732, "Hypotension": 2.433513630183765, "Nasal congestion": 27.12149106958791, "Orthostatic hypotension": 25.10893854031771, "Pollakiuria": 14.650789830120049, "Retrograde ejaculation": 2112.8729472760488, "Syncope": 2.897434440441335}
\ No newline at end of file
diff --git a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/999.json b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/999.json
index d991cf77681..e45def97b60 100644
--- a/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/999.json
+++ b/docs/SymptomsCausedByDrugs/data/ProportionalReportingRatios/vaccines/999.json
@@ -1 +1 @@
-{"Abscess limb ": 27.31409671249371, "Acne ": 3.2689167459726987, "Apnoea ": 12.316305373243914, "Autoimmune thyroiditis ": 14.285540665721554, "Blood alkaline phosphatase increased ": 3.775187826782616, "Blood follicle stimulating hormone increased ": 128.62945455890866, "Brain neoplasm ": 32.95469153570535, "Cerebral infarction ": 3.2111979663106425, "Condition aggravated ": 2.159508749101408, "Contusion ": 3.217902387412193, "Craniopharyngioma ": 626.4802843396005, "Dehydration ": 3.0906426770053077, "Diabetes mellitus ": 5.843430255987122, "Disease recurrence ": 10.460935280923849, "Drug abuse ": 4.682739818575517, "Drug-induced liver injury ": 10.747992718368042, "Eating disorder ": 4.873289348430135, "Electrolyte imbalance ": 9.670530122271732, "Enteritis ": 18.699391002719537, "Epiphysiolysis ": 722.4450930132522, "Fluid retention ": 3.469666284043281, "Focal nodular hyperplasia ": 148.3289695208738, "Focal segmental glomerulosclerosis ": 77.75742512517103, "Gastrointestinal infection ": 38.17183352978912, "Glucose tolerance impaired ": 68.31341766630216, "Glycosylated haemoglobin increased ": 3.522666981774041, "Head injury ": 4.360510550601289, "Hepatic cirrhosis ": 26.67277078647569, "Hepatic encephalopathy ": 44.40357586596575, "Hepatic necrosis ": 118.82859525466692, "Hepatomegaly ": 11.912783809452428, "Hepatotoxicity ": 13.493550296518764, "Hypoglycaemia ": 2.576678649672792, "Hyponatraemic seizure ": 386.1438015596223, "Hypophagia ": 6.471100344467632, "Idiopathic intracranial hypertension ": 241.6653602346964, "Increased appetite ": 10.64671010133172, "Injection site atrophy ": 88.83987535467666, "Injection site bruising ": 10.547298936069764, "Injection site haemorrhage ": 9.86754881187074, "Insulin resistance ": 35.62490278094377, "Insulin-like growth factor increased ": 278.57056558083264, "Intentional product misuse ": 2.0170800566277776, "Intracranial pressure increased ": 58.61924593764471, "Lower limb fracture ": 9.307119250187409, "Meningioma ": 56.60556288884906, "Myocardial fibrosis ": 99.93713553370924, "Neoplasm recurrence ": 93.530186464796, "Obstructive sleep apnoea syndrome ": 93.44473712164935, "Oesophageal disorder ": 49.96482074252936, "Off label use ": 3.064367880555756, "Pancreatitis acute ": 6.354695258301056, "Panniculitis ": 25.471415284247072, "Papilloedema ": 23.66846701604428, "Pituitary tumour benign ": 63.016160763225535, "Pleural adhesion ": 349.2422085660759, "Product dose omission issue ": 2.4982479017417747, "Product prescribing error ": 10.437622371213305, "Protein-losing gastroenteropathy ": 185.394968085309, "Scoliosis ": 87.56623486100816, "Sleep apnoea syndrome ": 37.15198603838651, "Snoring ": 88.88864192627597, "Stress ": 2.4625437485970263, "Sudden death ": 18.379653723577015, "Sulphaemoglobinaemia ": 1290.8221809123604, "Therapeutic response unexpected ": 3.0383413805651585, "Tonsillar disorder ": 271.355272624483, "Type 1 diabetes mellitus ": 7.415810809777687, "Type 2 diabetes mellitus ": 6.847951891042719, "Viral infection ": 4.7167327495039295}
\ No newline at end of file
+{"Alanine aminotransferase increased": 2.885063112311953, "Ascites": 7.538686831364737, "Aspartate aminotransferase increased": 2.9123573867681998, "Blood bilirubin increased": 14.569413886960778, "Blood creatinine increased": 3.510474653105271, "Death": 2.070935707180888, "Drug hypersensitivity": 2.618375889150215, "Drug ineffective": 8.257333139074223, "Drug interaction": 6.683616115460725, "Hepatic failure": 7.729320461372979, "Hepatic function abnormal": 2.908375892489848, "Hepatitis B reactivation": 51.36221335161509, "Hepatitis C": 234.90436308015376, "Hyperbilirubinaemia": 37.07307716573468, "Jaundice": 6.590644487737361, "Off label use": 11.20699905855128, "Pancreatitis acute": 7.570739143679191, "Photosensitivity reaction": 23.011967925880302, "Product use issue": 14.839077771030553, "Remission not achieved": 615.722476591015, "Sinus bradycardia": 25.700989384498843, "Treatment failure": 20.24657257766281}
\ No newline at end of file
diff --git a/src/data/prrByDrugAndSymptom-EudraVigilance.7z b/src/data/prrByDrugAndSymptom-EudraVigilance.7z
index 54dace72703..c2977d607f1 100644
Binary files a/src/data/prrByDrugAndSymptom-EudraVigilance.7z and b/src/data/prrByDrugAndSymptom-EudraVigilance.7z differ